pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Insect-derived Protein Supplements on Protein Synthesis and mTORC1 Activation
Status: ACTIVE_NOT_RECRUITING
Conditions: Effect of Food Supplement
Interventions: DIETARY_SUPPLEMENT: Whey protein|DIETARY_SUPPLEMENT: IPC80|DIETARY_SUPPLEMENT: Whole Buffalo Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Houtou Jianweiling Tablet in the Treatment of Chronic Non-Atrophic Gastritis
Status: COMPLETED
Conditions: Gastritis
Interventions: OTHER: Houtou Jianweiling tablet|DRUG: Omeprazole Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Broccoli Sprouts as a Nutritional Supplement in the Prevention of Cardiovascular Disease
Status: COMPLETED
Conditions: Diabetes Mellitus|Hypertension|Hypercholesterolemia|Cardiovascular Disease
Interventions: BEHAVIORAL: Daily intake of broccoli sprouts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The Impact of Intervention With High-protein Enteral Formula in SICU.
Status: COMPLETED
Conditions: Enteral Nutrition|Critical Illness
Interventions: OTHER: Very-high protein enteral formula|OTHER: Standard-high protein enteral formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Genes and Other Risk Factors for Second Primary Breast Cancer in Women With Breast Cancer and Their Female Family Members and Friends
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: GENETIC: DNA analysis|GENETIC: genetic linkage analysis|GENETIC: loss of heterozygosity analysis|GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis|OTHER: medical chart review|OTHER: questionnaire administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low Intensity Versus Self-guided Internet-delivered Psychotherapy for Major Depression
Status: COMPLETED
Conditions: Depression
Interventions: OTHER: Low Intensity Internet-delivered psychotherapy|OTHER: Self-guided Internet delivered psychotherapy|OTHER: Improved treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Omega 3 Fatty Acids in the Treatment of Children With Autism Spectrum Disorders
Status: COMPLETED
Conditions: Autism
Interventions: DRUG: Omega 3 fatty acids|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 14-Day Cumulative Irritation Patch Test in Subjects With Normal Skin - Chameleon
Status: COMPLETED
Conditions: Dermal Irritation
Interventions: DEVICE: Trojan "Chameleon" Personal Lubricant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Protein Supplementation and Exercise Training in Burn Patients
Status: COMPLETED
Conditions: Burns
Interventions: DIETARY_SUPPLEMENT: whey protein supplementation powder (Inkospor X-TREME; France)|OTHER: Exercise training program|OTHER: traditional burn care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Nerinetide (NA-1) in Subjects Undergoing Endovascular Thrombectomy for Stroke
Status: COMPLETED
Conditions: Stroke, Acute
Interventions: DRUG: Nerinetide (NA-1), 2.6 mg/kg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of the Motivational Deficit in Schizophrenia and Depression
Status: UNKNOWN
Conditions: Schizophrenia|Depression
Interventions: BEHAVIORAL: Force task, preference task, discount task, learning task.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of 4-Demethyl-4-cholesteryloxycarbonylpenclome (DM-CHOC-PEN) in Patients With Brain Tumors
Status: COMPLETED
Conditions: Primary Brain Tumors|Metastatic Malignant Neoplasm to Brain
Interventions: DRUG: 4-Demethyl-4-cholestryloxycarbonylpenclomedine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Genetically Targeted Enzyme Replacement Therapy for Advanced Heart Failure
Status: COMPLETED
Conditions: Heart Failure, Congestive|Dilated Cardiomyopathy
Interventions: GENETIC: MYDICAR Phase 1 (Open-label, Serial Dose-Escalation Study)|PROCEDURE: Placebo Infusion|GENETIC: MYDICAR Phase 2 (Placebo-controlled, Randomized Study)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgery With or Without Radiation Therapy in Untreated Nonmetastatic Retroperitoneal Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: PROCEDURE: therapeutic conventional surgery|RADIATION: 3-dimensional conformal radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Efficacy and Safety of X0002 in Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: KNEE OSTEOARTHRITIS
Interventions: DRUG: X0002 Spray|DRUG: Ibuprofen Tablet|DRUG: Ibuprofen Placebo Tab|DRUG: X0002 Placebo Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COGNITIVE - Cognitive Function After Sevoflurane or Propofol Anesthesia for Open-heart Operations
Status: WITHDRAWN
Conditions: Other Functional Disturbances Following Cardiac Surgery|Memory Disorders
Interventions: DRUG: Diprivan (propofol, Astra Zeneca)|DRUG: Sevorane (sevoflurane, Abbott)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Geriatric Assessment & Genetic Profiling to Personalize Therapy in Older Adults With Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Therapy-Related Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|DRUG: Decitabine|DRUG: Idarubicin|OTHER: Laboratory Biomarker Analysis|DRUG: Liposome-encapsulated Daunorubicin-Cytarabine|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Azacitidine|DRUG: Venetoclax|DRUG: glasdegib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Effects of Esketamine in Surgical Patients
Status: WITHDRAWN
Conditions: Surgical Injury
Interventions: DRUG: Esketamine Hydrochloride 28 Mg in 0.2 mL NASAL SOLUTION [Spravato]|DRUG: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Specificity and Sensitivity of 5- Aminolevulinic Acid (ALA) Fluorescence in Malignant Brain Tumors
Status: COMPLETED
Conditions: Brain Neoplasms
Interventions: DRUG: Tumor fluorescence
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lower But More Frequent Dose Rituximab to Treat Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Refractory Chronic Lymphocytic Leukemia
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double-method Comparative Study in Order to Predict the Use of Co-receptors From Type 1 HIV: Phenotypic Study (Trofile ESTA®) and Virologic Response to a CCR5 Antagonist in the Short Term
Status: COMPLETED
Conditions: HIV Infections
Interventions: OTHER: Maraviroc + Trofile ESTA® (diagnose test)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Examining Cognitive Function and Brain Abnormalities in Adults With Sickle Cell Disease - Pilot Intervention Study
Status: COMPLETED
Conditions: Anemia, Sickle Cell
Interventions: PROCEDURE: Monthly blood transfusion regimen|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Effectiveness of Applying Dry Local Heat and/ or High Tourniquet Pressure for Venipuncture.
Status: COMPLETED
Conditions: Venipuncture|Healthy Adult
Interventions: DEVICE: Dry heat|DEVICE: High pressure|DEVICE: Combination of dry heat and high pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study in Healthy Male Volunteers Investigating the Safety, Absorption and Elimination of Single Doses of GLPG4059
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: GLPG4059 oral suspension|DRUG: Placebo|DRUG: GLPG4059 tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Effect of Injection Site on PK of Astegolimab in Healthy Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: Astegolimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Vitamin E on Pediatric Nonalcoholic Fatty Liver Disease (NAFLD)
Status: COMPLETED
Conditions: Inflammation|Fibrosis|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Vitamin treatment (alpha tocopherol plus ascorbic acid)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Diffuse Large B Cell Lymphoma
Status: UNKNOWN
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Yangzhengxiaoji capsule combined with CHOP regimen|DRUG: CHOP regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Tri Fluvac, a Seasonal Trivalent Inactivated Split Virion Influenza Vaccine, in Healthy Thai Elderly
Status: UNKNOWN
Conditions: Influenza
Interventions: BIOLOGICAL: GPO Tri Fluvac vaccine|BIOLOGICAL: Licensed influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Benzodiazepine Discontinuation in Opioid Agonist Therapy
Status: COMPLETED
Conditions: Substance Use Disorders
Interventions: BEHAVIORAL: Distress Tolerance - Benzodiazepine Discontinuation (DT-BD)|DRUG: BZD discontinuation protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First in Human Feasibility Study to Evaluate the Safety and Effectiveness of the BIOTRONIK Prospera SCS System With HomeStream Remote Management
Status: RECRUITING
Conditions: Chronic Low-back Pain|Chronic Leg Pain
Interventions: DEVICE: Permanent implant of a BIOTRONIK Prospera SCS (Spinal Cord Stimulation) System with HomeStream Remote Management
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Cardiovascular Effects of 1:100,000 and 1:200,000 Epinephrine Solutions
Status: COMPLETED
Conditions: Cardiovascular Response to Epinephrine
Interventions: DRUG: Epinephrine 1:100,000|DRUG: Epinephrine 1:200,000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: XILO-FIST, the Effect of Allopurinol on the Brain Heart and Blood Pressure After Stroke
Status: COMPLETED
Conditions: Ischaemic Stroke
Interventions: DRUG: Allopurinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mandibular Ridge Splitting Versus Khoury Shell Technique
Status: COMPLETED
Conditions: Horizontal Augmentation of Atrophic Posterior Mandible
Interventions: PROCEDURE: ridge splitting in group and khoury shell technique in the other group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Sodium and Fructose on Blood Pressure and Inflammation
Status: RECRUITING
Conditions: Blood Pressure|Inflammation
Interventions: DIETARY_SUPPLEMENT: Recommended sodium and low fructose diet|DIETARY_SUPPLEMENT: High sodium and low fructose diet|DIETARY_SUPPLEMENT: High sodium and high fructose diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Supplementation of Bioactive Compounds on the Energy Metabolism of People Living With HIV / AIDS
Status: COMPLETED
Conditions: HIV Infections
Interventions: DIETARY_SUPPLEMENT: Curcumin|OTHER: Placebo of Curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Use of a OCT Probe in Assessment of Endoscopic and Surgical Resection Specimen of Gastrointestinal Tract
Status: COMPLETED
Conditions: Gastrointestinal Neoplasms
Interventions: DEVICE: Optical Coherence Tomography Probe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPα-CD47 Pathway, in Solid or Hematological Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|Refractory Non-Hodgkin Lymphoma
Interventions: DRUG: HCB101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Insulin Therapy for Post-transplant Glucocorticoid Induced Hyperglycemia
Status: TERMINATED
Conditions: Post-Transplant Glucocorticoid Induced Diabetes
Interventions: DRUG: Neutral protamine hagedorn (NPH) insulin|DRUG: Regular human insulin or Insulin Aspart|DRUG: Insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bezlotoxumab Efficacy and Tolerability in Cancer Patient
Status: UNKNOWN
Conditions: Clostridium Difficile Infection Recurrence
Interventions: DRUG: Bezlotoxumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of Risk in Thoracic Aortopathy Using 18F-Sodium Fluoride
Status: COMPLETED
Conditions: Bicuspid Aortic Valve|Thoracic Aortic Aneurysm|Aortic Dissection
Interventions: DIAGNOSTIC_TEST: clinical evaluation, blood markers, pulse wave analysis, 18F sodium fluoride PET/CT and PET/MRI|DIAGNOSTIC_TEST: Repeat 18F sodium fluoride PET/MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pericapsular Nerve Group Block vs Supra Inguinal Fascia Iliaca Compartment Block
Status: NOT_YET_RECRUITING
Conditions: Pain, Postoperative
Interventions: PROCEDURE: PENG + LFCN block versus S-FICB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sham Controlled Trial of Rapid Induction Percutaneous Tibial Nerve Stimulation
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DEVICE: PTNS treatment|DEVICE: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: NET in Iranian Women Suffering From Post Traumatic Stress Symptoms
Status: COMPLETED
Conditions: Mental Disorders|Domestic Violence
Interventions: BEHAVIORAL: Narrative Exposure Therapy|OTHER: Treatment-as-usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Evaluation of Magnetic Resonance Imaging Acquisition and Analysis Methods
Status: ENROLLING_BY_INVITATION
Conditions: Healthy
Interventions: BEHAVIORAL: MR Screening Questionnaire|DEVICE: Magnetic Resonance Imaging Acquisition and Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Water Intake and Weight Control in Older Adults
Status: RECRUITING
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Water intake and weight control in older adults - Premeal Water + hypocaloric diet|BEHAVIORAL: Water intake and weight control in older adults - Total Daily Water + hypocaloric diet|BEHAVIORAL: Water Intake and weight control in older adults - hypocaloric diet alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: De-escalation of Adjuvant Radio (Chemo) Therapy for HPV-positive Head-neck Squamous Cell Carcinomas
Status: RECRUITING
Conditions: Head-and-neck Squamous Cell Carcinoma
Interventions: RADIATION: De-escalation radio(chemo)therapy - Level 1|RADIATION: De-escalation radio(chemo)therapy - Level 2|RADIATION: Standard radio(chemotherapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study: Treatment of Relapsed Lymphoid Malignancies With an Anti-Angiogenic Approach
Status: TERMINATED
Conditions: Non-Hodgkin's Lymphoma|Cancer
Interventions: DRUG: Vincristine|DRUG: VP-16|DRUG: Rituximab|DRUG: Dexamethasone|DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of TKTX Cream on Pain and Fear in Children During Venipuncture: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Pain|Fear of Pain|Venipuncture Site Numbness
Interventions: DRUG: TKTX cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of GI Biome #7 on Gut Microbiome and Health of the Elderly
Status: COMPLETED
Conditions: Muscle Weakness
Interventions: DIETARY_SUPPLEMENT: GI Biome #7|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of an Investigational Cannabinoid and Methadone for HIV-associated Neuropathy
Status: WITHDRAWN
Conditions: HIV-associated Neuropathy|Polyneuropathy
Interventions: DRUG: SAB378|DRUG: methadone|DRUG: SAB placebo|DRUG: Methadone placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Molecular Weight of HA for Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Sono-guided injection with high molecular weight hyaluronic acid|PROCEDURE: Sono-guided injection with low molecular weight hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Duloxetine 60 mg With Regards to Reference Product in Feeding Conditions
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Duloxetine 60mg Test Drug Enteric Coated Granules|DRUG: Duloxetine 60mg Reference Product Enteric Coated Granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact of Structured Patient Education Material (SPEM) in Improving Clinical and Behavioural Outcomes in Home-based Cardiac Rehabilitation Program Participants: A Pilot Study
Status: UNKNOWN
Conditions: Ischaemic Heart Disease
Interventions: OTHER: Digital Structured Patient Education Material
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase I Multiple Ascending Dose Study for AZD 7268 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD7268|DRUG: AZD7268|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Psychotherapy Strategies for the Treatment of Professionals and Students From Essential Services With High Levels of Emotional Distress in the Context of COVID-19
Status: UNKNOWN
Conditions: Mental Disorder|COVID|Emotional Distress|Depression|Anxiety|Irritable Mood
Interventions: BEHAVIORAL: Cognitive Behavioral Brief-Telepsychotherapy|BEHAVIORAL: Brief Interpersonal Telepsychotherapy|BEHAVIORAL: Telepsychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Organization of Pulmonary Rehabilitation of Post-COVID-19 Patient With Sequelae (REHABCOVID)
Status: COMPLETED
Conditions: Covid19
Interventions: OTHER: Respiratory rehabilitation program (RR).|OTHER: Respiratory tele-rehabilitation program (TRR).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Assess the Safety and Effectiveness of Beltavac® Polymerized With Alternaria Alternata
Status: COMPLETED
Conditions: Rhinoconjunctivitis With or Without Allergic Asthma
Interventions: BIOLOGICAL: Beltavac® Polymerized with Alternaria alternata
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Stimulant Drugs on Social Perception
Status: COMPLETED
Conditions: Healthy|MDMA ('Ecstasy')
Interventions: DRUG: 3,4-Methylenedioxymethamphetamine|DRUG: methamphetamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Axitinib Implant) in Subjects With Neovascular Age- Related Macular Degeneration
Status: RECRUITING
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: OTX-TKI|DRUG: Aflibercept|DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Effectiveness of Serum Chromogranin A Levels on Diagnostic of Pancreatic Neuroendocrine Tumors
Status: UNKNOWN
Conditions: Non Functioning Pancreatic Endocrine Tumor
Interventions: BIOLOGICAL: Chromogranin A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Telehealth Program in Chronic Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Heart Failure
Interventions: OTHER: Home-based telehealth program|OTHER: Home-based rehabilitation|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Predict&Prevent: Use of a Personalised Early Warning Decision Support System to Predict and Prevent Acute Exacerbations of COPD
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: COPDPredict mobile App|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Measurement Of Cerebral Oxygenisation With NIRS Method İn Polycythaemic Infants Might Add A Criterion To Indicate PPET?
Status: UNKNOWN
Conditions: Cerebral Oxygenation|Peripheric Oxygenation|Polycythaemic Infants
Interventions: DEVICE: INVOS 5100
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sorafenib Study: Dosing in Patients With Pulmonary Arterial Hypertension (PAH)
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metronomic Chemotherapy in Patients With Advanced Solid Tumor With Bone Metastasis and Advanced Pretreated Osteosarcoma
Status: COMPLETED
Conditions: Solid Tumor|Osteosarcoma
Interventions: DRUG: Sirolimus combined with CP, MT and ZA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Enteral Nutrition and Corticosteroid on Intestinal Flora in Induction Remission of Crohn Disease in Adult
Status: UNKNOWN
Conditions: Crohn Disease
Interventions: DIETARY_SUPPLEMENT: enteral nutrition|DRUG: corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Pediatric Deep Brain Stimulation Registry
Status: RECRUITING
Conditions: Dystonia|Epilepsy in Children|Cerebral Palsy|Tourette Syndrome|Obsessive-Compulsive Disorder|Neurologic Disorder|Movement Disorders in Children|Movement Disorders|Deep Brain Stimulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low Dose Ipilimumab With Pembrolizumab in Treating Patients With Melanoma That Has Spread to the Brain
Status: ACTIVE_NOT_RECRUITING
Conditions: Clinical Stage IV Cutaneous Melanoma AJCC v8|Metastatic Malignant Neoplasm in the Brain|Metastatic Melanoma|Pathologic Stage IV Cutaneous Melanoma AJCC v8
Interventions: BIOLOGICAL: Ipilimumab|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retrolaminar Block for Pediatric Thoracoscopic Sympathectomy
Status: RECRUITING
Conditions: Pediatric Thoracoscopy
Interventions: PROCEDURE: Retrolaminar block|PROCEDURE: paravertebral group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antisecretory Factor (AF) Effects on Intraocular-pressure
Status: TERMINATED
Conditions: Glaucoma
Interventions: DIETARY_SUPPLEMENT: Salovum|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regulation of Intestinal and Hepatic Lipoprotein Secretion by Resveratrol
Status: COMPLETED
Conditions: Dyslipidaemia|Insulin Resistance
Interventions: DRUG: Resveratrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Breastfeeding Education and Skin-to-Skin Contact on Breastfeeding Efficiency and Maternal Attachment
Status: COMPLETED
Conditions: Breastfeeding|Postpartum|Infant Development
Interventions: BEHAVIORAL: Group A|OTHER: Group B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: First-in-human Safety and Immunogenicity Study of SCB-1019 in Healthy Adults
Status: RECRUITING
Conditions: Respiratory Syncytial Virus Infection
Interventions: BIOLOGICAL: Candidate vaccine, SCB-1019|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Individualized Dose Study of ATG in Haploidentical Hematopoietic Stem Cell Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Haploidentical Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Antithymocyte Globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of TENS of Intestınal Functıons, Pain and Analgesis Consumptıon Amount
Status: NOT_YET_RECRUITING
Conditions: Colorectal Surgery|Pain, Postoperative
Interventions: DEVICE: TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Study Between Platelet Rich Plasma and Steroid Injection in Trigger Finger Treatment
Status: NOT_YET_RECRUITING
Conditions: Trigger Finger Disorder
Interventions: BIOLOGICAL: Platelet rich plasma|DRUG: Pfizer Depo-medrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study on Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment of Bipolar Depression
Status: COMPLETED
Conditions: Mood Disorder|Bipolar Disorder|Major Depression|Depression
Interventions: DEVICE: Magnetic Stimulator Rapid2 made by Magstim Company Ltd. U.K.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effects of Quinoa Consumption on Markers of Cardiovascular Risk and Gastrointestinal Health
Status: UNKNOWN
Conditions: Change in Fasting Plasma LDL-cholesterol Concentration After the Consumption of Quinoa
Interventions: DIETARY_SUPPLEMENT: Quinoa|DIETARY_SUPPLEMENT: Wheat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial for Dose Finding and Safety of RVX000222 in Subjects With Stable Coronary Artery Disease
Status: COMPLETED
Conditions: Atherosclerosis|Coronary Artery Disease
Interventions: DRUG: RVX000222|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plerixafor and Sargramostim (GM-CSF) for Mobilization of Allogeneic Sibling Donors
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute|Myelodysplastic Syndromes|Lymphoma, Non-Hodgkin|Hodgkin Disease|Leukemia, Lymphocytic, Chronic, B-Cell|Multiple Myeloma
Interventions: DRUG: Sargramostim|DRUG: Plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin Effects on Hypoglycemia
Status: COMPLETED
Conditions: Type1 Diabetes Mellitus
Interventions: DRUG: Dapagliflozin 5mg|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SCD-PROMIS: A Software Platform to Enhance Self-efficacy and Patient-provider Engagement for Patients With Sickle Cell Pain
Status: COMPLETED
Conditions: Sickle Cell Disease|Anemia|Anemia, Hemolytic|Anemia, Sickle Cell|Hematologic Diseases
Interventions: OTHER: PROMIS for Pain Management App
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Hydroxychloroquine to Improve Insulin Sensitivity in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Insulin Resistance
Interventions: DRUG: Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Cryotherapy in the Prevention of Nails Toxicity Induced by Taxotere® in Breast or Prostate Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Prostate Cancer|Nail Diseases
Interventions: PROCEDURE: Frozen Glove
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of NAC on Sleep Apnea
Status: UNKNOWN
Conditions: ESRD|Sleep Apnea
Interventions: DRUG: Oral N-Acetylcysteine 1200 mg x 2/day for 4 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurological Effects of Chemotherapy and Radiation Therapy in Patients With Colon Cancer
Status: COMPLETED
Conditions: Cognitive/Functional Effects|Colorectal Cancer|Long-term Effects Secondary to Cancer Therapy in Adults
Interventions: PROCEDURE: cognitive assessment|PROCEDURE: magnetic resonance imaging|PROCEDURE: management of therapy complications
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Device FLEXITHERALIGHT Compared to the Conventional Photodynamic Therapy
Status: TERMINATED
Conditions: Keratosis, Actinic
Interventions: DEVICE: FLEXITHERALIGHT PDT|DEVICE: Aktilite® Galderma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GLS-010 Monotherapy Versus Chemotherapy in Patients With Relapsed or Refractory Classical Hodgkin's Lymphoma (R/R cHL)
Status: NOT_YET_RECRUITING
Conditions: Classic Hodgkin's Lymphoma|Recurrent Classic Hodgkin Lymphoma|Refractory Classic Hodgkin Lymphoma
Interventions: DRUG: GLS-010|DRUG: Chemotherapy of Investigator's choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance Treatment of Anemia Associated With Chronic Kidney Disease (CKD) in Hemodialysis Subjects on Epoetin Alfa / Beta Treatment Versus BAY85-3934
Status: COMPLETED
Conditions: Anemia|Renal Insufficiency, Chronic
Interventions: DRUG: Molidustat (BAY 85-3934)|BIOLOGICAL: Epoetin alfa/beta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Isavuconazole (BAL8557) in the Treatment of Candidemia and Other Invasive Candida Infections
Status: COMPLETED
Conditions: Candidiasis, Invasive|Candidemia|Mycoses
Interventions: DRUG: Isavuconazole|DRUG: Caspofungin|DRUG: Voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gemox Combined With Anlotinib and Sintilimab in Advanced cHCC-ICC
Status: NOT_YET_RECRUITING
Conditions: Combined Hepatocellular Cholangiocarcinoma
Interventions: DRUG: gemcitabine ,oxaliplatin,anlotinib,Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ixazomib With Cyclophosphamide and Dexamethasone in Patients With Previously Untreated Symptomatic Multiple Myeloma or Light Chain Amyloidosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Amyloidosis|Plasma Cell Myeloma
Interventions: DRUG: Cyclophosphamide|DRUG: Dexamethasone|DRUG: Ixazomib Citrate|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sustained Inflation and Chest Compression vs 3:1 C:V Ratio in Asphyxiated Newborns
Status: NOT_YET_RECRUITING
Conditions: Cardiac Arrest
Interventions: PROCEDURE: CC+SI (Chest compression during sustained inflation)|PROCEDURE: 3:1 C:V (3:1 Compression:Ventilation ratio)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact on Mental and Physical Health of Caring for Women Who Are Victims of Sexual and Gender-based Violence, Using a Coordinated Multidisciplinary Approach in Women's Centres or Traditional Health Centres.
Status: NOT_YET_RECRUITING
Conditions: Domestic and/or Sexual Violence
Interventions: OTHER: completion of scales and questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Vedolizumab (MLN0002) in Patients With Moderate to Severe Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: vedolizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise, Sleep Quality and Nocturnal Fat Oxidation in Metabolic Syndrome
Status: TERMINATED
Conditions: Metabolic Syndrome|PreDiabetes|Hypertension|Obesity|Hyperlipidemias
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neoadjuvant Tislelizumab Plus Chemotherapy for Resectable Locally-advanced Head and Neck Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinomas|Resectable Head and Neck Squamous-cell Carcinoma
Interventions: DRUG: Tislelizumab|DRUG: Nab-paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Pharmacodynamics and Safety of Biphasic Insulin Aspart 30 in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 30|DRUG: biphasic human insulin 30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Panobinostat (LBH589) and Imatinib Mesylate in Treating Patients With Previously Treated Chronic Phase Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: imatinib mesylate|DRUG: panobinostat|GENETIC: polymerase chain reaction|GENETIC: protein expression analysis|GENETIC: western blotting|OTHER: flow cytometry|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Use of the RELAX® Glasses on the Anxiety of Patients Undergoing Emergency Hand Surgery Under Locoregional Anesthesia
Status: COMPLETED
Conditions: Surgery
Interventions: BEHAVIORAL: RELAX® glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ascitic Fluid Calprotectin as an Accurate Diagnostic Marker for Spontaneous Bacterial Peritonitis
Status: UNKNOWN
Conditions: Spontaneous Bacterial Peritonitis
Interventions: DIAGNOSTIC_TEST: ascitic fluid calprotectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Telenursing Interventions in Empowering Patients With COPD
Status: RECRUITING
Conditions: Copd|Empowerment|Empowerment, Patient|Self Efficacy
Interventions: OTHER: Telenursing Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparative Clinical Study of Different Caries Removal Techniques in Pediatric Patients
Status: COMPLETED
Conditions: Dental Caries in Children
Interventions: DEVICE: Rotary handpieces|DEVICE: Er:YAG laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sodium Hypoclorite as an Antibacterial Agent Prior to Pulpotomies
Status: COMPLETED
Conditions: Pulpotomy|Primary Teeth
Interventions: OTHER: CH Pulpotomy, physiologic saline|OTHER: CH pulpotomy, NaOCl|OTHER: MTA Pulpotomy, physiologic saline|OTHER: MTA pulpotomy, NaOCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GSK573719 IV Enabling Study
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK573719 (SOLUTION)|DRUG: GSK573719 (INHALATION POWDER)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess BOTOX Injections for the Change of Masseter Muscle Prominence in Adult Participants
Status: RECRUITING
Conditions: Masseter Muscle Prominence
Interventions: DRUG: BOTOX|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Sarilumab in Patients With Polymyalgia Rheumatica
Status: TERMINATED
Conditions: Polymyalgia Rheumatica
Interventions: DRUG: Sarilumab SAR153191 (REGN88)|DRUG: Sarilumab-matching placebo|DRUG: Prednisone|DRUG: Prednisone-matching placebo|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemtuzumab Ozogamicin With G-CSF, Cladribine, Cytarabine & Mitoxantrone for Untreated AML & High-Grade Myeloid Neoplasm
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Cladribine|DRUG: Cytarabine|DRUG: Gemtuzumab Ozogamicin|BIOLOGICAL: Recombinant Granulocyte Colony-Stimulating Factor|OTHER: Laboratory Biomarker Analysis|DRUG: Mitoxantrone Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Trial to Assess the Improvement of Adverse Events in Chronic Myelogenous Leukemia Patients Treated With Imatinib When Switched to Nilotinib Treatment
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia
Interventions: DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Continuous Subcutaneous Insulin Infusion Versus Basal-bolus Multiple Daily Injections Regimen in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Detemir insulin, Aspart insulin, Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Profile of PETALO CVS in the Treatment of Non-thrombotic Internal Jugular Vein Stenosis and Chronic Headache
Status: UNKNOWN
Conditions: Headache|Jugular Vein Occlusion
Interventions: DEVICE: PTA + Stenting using "Petalo stent"|PROCEDURE: Percutaneous Transluminal Angioplasty (PTA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma in Women With Urinary Incontinence
Status: UNKNOWN
Conditions: Urinary Incontinence|Stress Urinary Incontinence
Interventions: BIOLOGICAL: Platelet Rich Plasma Injections|OTHER: Normal Saline Injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of TNF-Antagonism in Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DRUG: Etanercept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety, Tolerability, PK and the Food Effect on PK of ASC11/RTV Tablets in Healthy Subjects
Status: RECRUITING
Conditions: Healthy|COVID-19
Interventions: DRUG: ASC11 tablets|DRUG: Placebo|DRUG: RTV tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Hepatic Arterial Infusion Chemotherapy (HAIC) Combine Lenvatinib and Durvalumab (HILL) in Advanced Hepatocellular Carcinoma (HCC)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Hepatic Arterial Infusion Chemotherapy (HAIC) Combine Lenvatinib and Durvalumab (HILL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Restoration After Abdominal and Pelvic Laparoscopic Surgery: Effect of Perioperative Intravenous Lidocaine
Status: COMPLETED
Conditions: Colon Cancer|Inflammatory Bowel Diseases|Diverticulitis
Interventions: DRUG: Lidocaine|PROCEDURE: Epidural Block|DRUG: PCA Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT