pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Metabolic Impact of Dietary Protein Supplementation in Surgical Weight Loss
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: GBP-SPS|DIETARY_SUPPLEMENT: GBP-HPS|DIETARY_SUPPLEMENT: VSG-SPS|DIETARY_SUPPLEMENT: VSG-HPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Self-efficacy Predict Outcomes Among U.S. Military Academy Cadets During Initial Entry Training?
Status: UNKNOWN
Conditions: Low Back Pain|Musculoskeletal Injury
Interventions: BEHAVIORAL: Deadlift Form Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Intramyocardial Stem Cell Therapy in Patients With Dilated Cardiomyopathy
Status: COMPLETED
Conditions: Dilated Cardiomyopathy|Chronic Heart Failure
Interventions: PROCEDURE: Intramyocardial injection|PROCEDURE: Intracoronary injection|PROCEDURE: Intramyocardial injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Soy Isoflavone on Bone Health Among Saudi Female Students Imam Abdulrahman Bin Faisal University.
Status: COMPLETED
Conditions: Soy Isoflavone Effect|Bone Density, Low|Bone Density Increased
Interventions: DIETARY_SUPPLEMENT: Soy Isoflavone supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clofarabine and Cyclophosphamide in Treating Patients With Relapsed or Refractory Acute Leukemia, Chronic Myelogenous Leukemia, or Myeloproliferative Disorders
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Myelodysplastic/Myeloproliferative Diseases
Interventions: DRUG: clofarabine|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Personalized Anti-Inflammatory Fibres in Ulcerative Colitis
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: Acacia Gum|DIETARY_SUPPLEMENT: Microcrystalline Cellulose|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of 3% Topical Tranexamic Acid Compared to 4% Topical Hydroquinone as Therapy of Melasma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melasma
Interventions: DRUG: 3 % Topical Tranexamic Acid|DRUG: 4% Topical Hidroquinone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Additive Effects of Clonidine Used in Propofol Sedation in Colonoscopy
Status: RECRUITING
Conditions: Clonidine|Propofol|Sedation|Colonoscopy
Interventions: DRUG: Propofol|DRUG: Propofol combined with clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Single-ascending Dose Study to Evaluate Safety and Tolerability of MEDI4920 in Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: BIOLOGICAL: MEDI4920 3 mg|BIOLOGICAL: MEDI4920 10 mg|BIOLOGICAL: MEDI4920 30 mg|BIOLOGICAL: MEDI4920 100 mg|BIOLOGICAL: MEDI4920 300 mg|BIOLOGICAL: MEDI4920 1000 mg|BIOLOGICAL: MEDI4920 3000 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Saphenous Nerve Block: Single Shot Versus Continuous Infusion to Supplement a Continuous Sciatic Nerve Block After Major Ankle Surgery
Status: COMPLETED
Conditions: Major Ankle Surgery
Interventions: PROCEDURE: Continuous saphenous nerve block|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D HIV Study on Postmenopausal Women
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Vitamin D3|OTHER: Placebo|DRUG: Vitamin Supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Rivaroxaban Reversal by Ciraparantag as Measured by WBCT
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ciraparantag|DRUG: Placebo|DRUG: Rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Open Label, Dose-escalation Study of the Safety, Pharmacokinetics and Antiretroviral Activity of 3BNC117
Status: COMPLETED
Conditions: Healthy|HIV
Interventions: BIOLOGICAL: 1 mg/kg, single dose IV administration of 3BNC117|BIOLOGICAL: 3 mg/kg, single dose IV administration of 3BNC117|BIOLOGICAL: 10 mg/kg, single dose IV administration of 3BNC117|BIOLOGICAL: 30 mg/kg, single dose IV administration of 3BNC117|BIOLOGICAL: 10 mg/kg, two doses IV of 3BNC117|BIOLOGICAL: 30 mg/kg, two doses IV of 3BNC117
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Outcomes of Perforation After Colorectal Endoscopic Submucosal Dissection
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Neoplasms|Perforation of Rectum|Perforation Colon
Interventions: PROCEDURE: Endoscopic submucosal dissection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interferon Alfa, Isotretinoin, and Paclitaxel in Treating Patients With Recurrent Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: interferon alpha|DRUG: 13-cis-retinoic acid|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metoprolol Treatment for Cytokine Release Syndrome in Patients Treated With Chimeric Antigen Receptor T Cells
Status: UNKNOWN
Conditions: Solid Tumor|Hematological Malignancy
Interventions: DRUG: Metoprolol|DRUG: metoprolol, infliximab, etanercept, tocilizumab and/or other agents
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: App-Based Mindfulness Training for Individuals With Anorexia Nervosa and Bulimia Nervosa
Status: RECRUITING
Conditions: Anorexia Nervosa|Bulimia Nervosa|Anorexia Nervosa, Atypical|Bulimia; Atypical
Interventions: BEHAVIORAL: Mindful Courage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Periacetabular Osteotomy With and Without Arthroscopic Management of Central Compartment Pathology
Status: RECRUITING
Conditions: Hip Dysplasia
Interventions: PROCEDURE: PAO with hip arthroscopy|PROCEDURE: PAO without hip arthroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Trastuzumab in Combination With TS-ONE and Cisplatin in Firstline Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Gastric Cancer
Status: COMPLETED
Conditions: HER 2 Positive Advanced Gastric Cancer
Interventions: DRUG: Trastuzumab, TS ONE, Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Immunogenicity of a 10-valent Pneumococcal Conjugate Vaccine in Preterm Infants
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Pneumococcal conjugate vaccine GSK1024850A|BIOLOGICAL: Infanrix hexa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Pharmacokinetics, Biodistribution, and Diagnostic Performance of [18F]GP1 PET in Thromboembolism
Status: COMPLETED
Conditions: Thromboembolism
Interventions: DRUG: [18F]GP1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Closed Loop Insulin Delivery for Glucose Control in Patients With Insulin Dependent Diabetes Mellitus After Kidney Transplantation
Status: WITHDRAWN
Conditions: Type 1 Diabetes|Insulin-requiring Type 2 Diabetes Mellitus|End Stage Renal Disease (ESRD)
Interventions: DEVICE: Artificial Pancreas|OTHER: Multiple Daily Injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Ph2b to Evaluate Tildacerfont in the Reduction of Glucocorticoid Steroid Doses in Adult CAH
Status: ACTIVE_NOT_RECRUITING
Conditions: Congenital Adrenal Hyperplasia
Interventions: DRUG: Tildacerfont/Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Eccentric Training and Cryotherapy Vs Eccentric Training and Whole Body Vibration in Achilles Tendinopathy
Status: COMPLETED
Conditions: Achilles Tendon|Tendinopathy
Interventions: OTHER: Cryotherapy and eccentric exercise|OTHER: Vibration and eccentric exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Burnout Among Caregivers Facing COVID-19 Health Crisis at a Non-conventional Intensive Care Unit Compared to a Conventional Intensive Care Unit
Status: UNKNOWN
Conditions: COVID-19|Burnout, Caregiver|Intensive Care Unit|Stress, Psychological
Interventions: OTHER: Patient management suffering of coronavirus infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Perioperative Chemotherapy With Bevacizumab for Colorectal Carcinomatosis
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: perioperative chemotherapy plus bevacizumab|PROCEDURE: cytoreductive surgery|DRUG: Intraperitoneal Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SpotCheck: Comparison of Enhanced Telemedicine Versus In-person Evaluation for the Diagnosis of Skin Cancer
Status: COMPLETED
Conditions: Skin Cancer
Interventions: DEVICE: Nevisense 3.0|DEVICE: Dermlite Cam|PROCEDURE: Skin biopsy|DEVICE: Barco Demetra
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Assess the Pharmacokinetic Drug-Drug Interactions of Lemborexant When Coadministered With an Oral Contraceptive, Famotidine, or Fluconazole in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: lemborexant|DRUG: Loestrin|DRUG: famotidine|DRUG: fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: EndoRotor DEN (Direct Endoscopic Necrosectomy)Trial
Status: COMPLETED
Conditions: Acute Pancreatic Necrosis|Acute Pancreatitis|Necrotizing Pancreatitis
Interventions: DEVICE: EndoRotor Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systemic Symptoms: Biospecimen Analysis Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Women With Breast Implants With and Without Self-reported Systemic Symptoms|Women Undergoing an Elective Mastopexy (Breast Lift) or Small Reduction
Interventions: PROCEDURE: Surgical collection of biospecimens
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ranibizumab for Polypoidal Choroidal Vasculopathy (PCV)
Status: COMPLETED
Conditions: Polypoidal Choroidal Vasculopathy
Interventions: DRUG: ranibizumab intravitreal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Inspiratory Muscle Training on Postural Control in Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: COPD Postural Control IMT
Interventions: OTHER: Complex pulmonary rehabilitation|OTHER: Inspiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Mobilized Peripheral Blood CD34+ Hematopoietic Stem and Progenitor Cells (HSPC) Transduced With the Elongation Factor Alpha Short Promoter (EFS) - Adenosine Deaminase (ADA) Gene (EFS-ADA) Lentiviral Vector for Adenosine Deaminase Severe Combined Immune Deficiency (ADA SCID)
Status: RECRUITING
Conditions: Adenosine Deaminase Severe Combined Immune Deficiency
Interventions: COMBINATION_PRODUCT: A cryopreserved formulation of autologous mPB CD34+ hematopoietic stem and progenitor cells transduced ex vivo with the EFS-ADA lentiviral vector encoding the human ADA enzyme
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Additional Effects of Perioperative Immunonutrition in Patients Undergoing Pancreaticoduodenectomy
Status: UNKNOWN
Conditions: Pancreatic Tumor|Bile Duct Tumor
Interventions: DIETARY_SUPPLEMENT: Oral IMPACT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study Assessing Safety and Efficacy of MD-15 Intraocular Lens in Patients With Aphakic Eye After Cataract Surgery
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: MD-15 Intraocular Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Low Dose Ketoconazole in Prostate Cancer That Does Not Respond to Hormone Therapy and Prior Chemotherapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Ketoconazole|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Evaluating a Ketogenic Diet Concomitant to Nivolumab and Ipilimumab in Patients With Metastatic Renal Cell Carcinoma
Status: RECRUITING
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DIETARY_SUPPLEMENT: Continuous ketogenic diet|DIETARY_SUPPLEMENT: Discontinuous ketogenic diet|DIETARY_SUPPLEMENT: beta-hydroxybutyrate (BHB) supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Phototherapy Treatment of Infected Diabetic Ulcers
Status: WITHDRAWN
Conditions: Diabetic Foot|Diabetic Foot Ulcer|Diabetes|Diabetes Mellitus|Infected Wound|Infected Ulcer of Skin
Interventions: DEVICE: Phototherapy|PROCEDURE: Debridement Surgery and Wound Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Multicenter, Phase III Trial to Assess Conformal Post-operative Radiotherapy vs. Surveillance After Complete Resection of Stage II/III Thymoma
Status: RECRUITING
Conditions: Thymoma Malignant Recurrent
Interventions: OTHER: Radiotherapy|OTHER: Surveillance after resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced-dose Chemotherapy Followed by Blinatumomab in Induction Therapy of Newly Diagnosed Non-elderly Ph-B-ALL
Status: COMPLETED
Conditions: B Acute Lymphoblastic Leukemia
Interventions: DRUG: Blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sacral Savers: Study of Prevention and Enhanced Healing of Sacral and Trochenteric Ulcers
Status: WITHDRAWN
Conditions: Healing Ulcer
Interventions: DEVICE: SacralSaver|OTHER: Standard Care of Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Delineation of the Diabetogenic Role of Extrapancreatic Glucagon in Totally Pancreatectomised Patients Using Glucagon Receptor Antagonism
Status: UNKNOWN
Conditions: Diabetes After Total Pancreatectomy
Interventions: DRUG: Glucagon receptor antagonist LY2409021|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Non-invasive Clinical Imaging of Cerebral Metabolism Following Brain Injury Using 13C Magnetic Resonance Spectroscopy.
Status: TERMINATED
Conditions: Traumatic Brain Injury
Interventions: DIAGNOSTIC_TEST: 13C magnetic resonance spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Couples Health Project: Couples-based Intervention to Reduce Drug Use and HIV Transmission Risk
Status: COMPLETED
Conditions: Risk Behavior|Drug Use|Sex, Anal
Interventions: BEHAVIORAL: Couples Health Project (CHP)|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Non-motor Symptoms, Balance, Muscle Strength, and Functional Mobility in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Balance|Muscle Strength|Mobility|Non-motor Symptoms
Interventions: OTHER: Non-Motor Symptoms|OTHER: Balance|OTHER: Lower Limb Strength|OTHER: Functional mobility
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Kegel Exercises With and Without Myofascial Release in Chronic Pelvic Pain
Status: COMPLETED
Conditions: Chronic Pelvic Pain Syndrome
Interventions: OTHER: Kegel Exercise|OTHER: Myofascial release technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Switching From Entecavir to Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis B
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Tenofovir Disoproxil Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cutaneous Tolerability and Safety of NVN1000 Topical Gel in Healthy Volunteers
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: 2% NVN1000 Topical Gel|DRUG: 4% NVN1000 Topical Gel|DRUG: 8% NVN1000 Topical Gel|DRUG: Vehicle Topical Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: rTMS Effects on Smoking Cessation and Cognition in Schizophrenia
Status: COMPLETED
Conditions: Cigarette Smoking|Schizophrenia
Interventions: PROCEDURE: Repetitive Transcranial Magnetic Stimulation (rTMS)|PROCEDURE: Sham Repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Selenium Supplementation on Trace Mineral Antioxidant Enzyme and Amino Acid Metabolism in Infants
Status: COMPLETED
Conditions: Preterm Infants
Interventions: OTHER: selenium and sodium selenate supplementation|OTHER: selenium and sodium selenite supplementation|OTHER: Without selenium and sodium selenate supplementation|OTHER: Without selenium and sodium selenite supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Stigma and Online Counseling to Increase HIV/STI Testing
Status: COMPLETED
Conditions: HIV/STI Testing
Interventions: BEHAVIORAL: Stigma and Structural Interventions|BEHAVIORAL: Health Information Seeking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Effects of a Prescription Omega-3 Fatty Acid Concentrate on Induced Inflammation
Status: COMPLETED
Conditions: Inflammatory Responses
Interventions: DRUG: 4 g prescription omega-3 concentrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intrauterine Injection of Human Chorionic Gonadotrophin and Pregnancy Rate in ICSI
Status: COMPLETED
Conditions: Repeated Implantation Failure
Interventions: DRUG: Human chorionic gonadotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Understanding Pain Mechanisms in Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis, Knee|Chronic Pain
Interventions: DRUG: Intra-articular injection of bupivacaine in the knee joint|DRUG: Intra-articular injection of placebo in the knee joint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: SIMPLICITY: Studying Impacts on Malabsorption With Liprotamase in Cystic Fibrosis
Status: COMPLETED
Conditions: Exocrine Pancreatic Insufficiency|Cystic Fibrosis
Interventions: DRUG: Liprotamase Powder for Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of BrainPhyt High Dose on Cognitive Function in Healthy Older Individuals
Status: COMPLETED
Conditions: Age-associated Memory Impairment
Interventions: DIETARY_SUPPLEMENT: Brainphyt high dose|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multimodality Treatment for Women With Stage II, Stage III, or Stage IV Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: paclitaxel|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bridging Brain Structure and Function by Correlating Structural Connectivity, Cortico-Cortical Transmission and Direct Electro-Stimulation
Status: COMPLETED
Conditions: Tumor, Brain
Interventions: OTHER: electrocorticography with electrostimulation|OTHER: dRMI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Surgical Incision Complications in Patients Receiving PICO or Standard Care Following Colorectal Surgery
Status: WITHDRAWN
Conditions: Wounds and Injuries
Interventions: DEVICE: PICO Softport V1.6|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Risperidone With Haloperidol in Patients With Schizophrenia and Schizoaffective Disorder
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: risperidone|DRUG: haloperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of Selinexor in Combination With Daunorubicin and Cytarabine for Untreated AML
Status: COMPLETED
Conditions: Leukemia|Acute Myeloid Leukemia|AML
Interventions: DRUG: Selinexor|DRUG: Daunorubicin|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab Combined With Carboplatin Plus Paclitaxel Chemotherapy to Treat Metastatic Mucosal Melanoma
Status: UNKNOWN
Conditions: Melanoma
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebellar Transcranial Direct Current Stimulation in Spinocerebellar Ataxia 38
Status: COMPLETED
Conditions: Spinocerebellar Ataxias
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib in Treating Patients With Recurrent or Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Colon|Adenocarcinoma of the Rectum|Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IV Colon Cancer|Stage IV Rectal Cancer
Interventions: DRUG: erlotinib hydrochloride|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Radiation Dosimetry Study Evaluating 99m TC-EC-DG SPECT/CT in Patients With Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: RADIATION: Radiolabeled (99Tc) EC-DG (ethylenedicysteine-deoxyglucose)|RADIATION: Technetium 99m ethylenedicysteine-deoxyglucose|RADIATION: 18 F fluorodeoxyglucose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Trial to Investigate Patch Adhesion of Rotigotine Containing Patches in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Rotigotine 8Mg/24Hrs Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mitotane With or Without Cisplatin and Etoposide After Surgery in Treating Patients With Stage I-III Adrenocortical Cancer With High Risk of Recurrence
Status: RECRUITING
Conditions: ENSAT Stage I Adrenal Cortex Carcinoma|ENSAT Stage II Adrenal Cortex Carcinoma|ENSAT Stage III Adrenal Cortex Carcinoma
Interventions: DRUG: Cisplatin|DRUG: Etoposide|DRUG: Mitotane|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thiamine as a Metabolic Resuscitator in Septic Shock
Status: COMPLETED
Conditions: Septic Shock
Interventions: DRUG: D5W|DRUG: Thiamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of AIN457 in Patients With Quiescent Non-infectious Uveitis
Status: TERMINATED
Conditions: Non-infectious Uveitis
Interventions: DRUG: AIN457|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Aripiprazole on Postoperative Analgesia in Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Anesthesia|Analgesia|Hysterotomy
Interventions: DRUG: ARIPiprazole 30 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determining Postoperative Recovery and the Impact of Adverse Events in Neurosurgery Based on Self-reported, App-based Longitudinal Assessment - a Collaborative Observational Research Project
Status: RECRUITING
Conditions: Disc Disease|Instabilities Lumbar|Brain Tumor|Aneurysm
Interventions: OTHER: OP-Tracker App
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Rituximab in Combination With Fludarabine and Cyclophosphamide in Participants With Chronic Lymphocytic Leukemia and Favorable Somatic Status
Status: TERMINATED
Conditions: Lymphocytic Leukemia, Chronic
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CRV431 Dosed Once Daily in NASH Induced F2 and F3 Subjects
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis|Fibrosis, Liver|NAFLD - Nonalcoholic Fatty Liver Disease
Interventions: DRUG: CRV431 75mg|DRUG: Placebo (1 softgel)|DRUG: CRV431 225mg|DRUG: Placebo (3 softgels)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oculometry as an Attentional Mechanism Evaluation Tool and Attention Deficit Hyperactivity Inhibition
Status: UNKNOWN
Conditions: Attention Deficit-Hyperactivity
Interventions: BEHAVIORAL: Neuropsychological tests|BEHAVIORAL: Oculometric tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PANHPVAX, Study of a New HPV Vaccine in Healthy Volunteers
Status: RECRUITING
Conditions: HPV
Interventions: BIOLOGICAL: Vaccination with PANHPVAX 10µg|BIOLOGICAL: Vaccination with PANHPVAX 40µg|BIOLOGICAL: Vaccination with PANHPVAX 100µg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Efficacy and Safety of HL151 Versus Placebo in Perennial Allergic Rhinitis Patients
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: HL151|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prednisone or Dexamethasone in Newly Diagnosed, Previously Untreated Primary Immune Thrombocytopenic Purpura
Status: COMPLETED
Conditions: Nonneoplastic Condition
Interventions: DRUG: dexamethasone|DRUG: prednisone|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using the Chinese Indigenization FS Scale in the Diagnosis of Fibromyalgia： Specificity and Sensitivity in Clinical Practice
Status: RECRUITING
Conditions: Fibromyalgia
Interventions: DIAGNOSTIC_TEST: The FM Diagnosis and Assessment Scale will be filled out, and there will be no other interventions beyond that
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety of Intramuscular Injections (IM) of Allogeneic PLX-PAD Cells for the Treatment of Critical Limb Ischemia (CLI)
Status: COMPLETED
Conditions: Peripheral Artery Disease|Peripheral Vascular Disease|Critical Limb Ischemia
Interventions: BIOLOGICAL: PLX-PAD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing a Controlled Human Infection Model for Group B Streptococcus (CHIM_GBS)
Status: UNKNOWN
Conditions: Group B Streptococcus
Interventions: PROCEDURE: rectovaginal swab|PROCEDURE: pregnancy test|PROCEDURE: Menstrual cup|PROCEDURE: Blood test|OTHER: Focus group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral Carnosine for Neuromuscular Performance in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DIETARY_SUPPLEMENT: Carnosine, capsulle, 2 g/day, 8 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Enhancing Exercise and Psychotherapy to Treat Pain and Addiction in Adults With an Opioid Use Disorder (EXPO; R33 Phase)
Status: RECRUITING
Conditions: Opioid Use Disorder|Pain
Interventions: OTHER: Exercise|BEHAVIORAL: Psychotherapy Pain and Addiction (I-STOP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Optimal Coherence Tomography Guidance and Angiography Guidance in Percutaneous Coronary Intervention
Status: UNKNOWN
Conditions: Coronary Disease
Interventions: DEVICE: OCT|DEVICE: Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: WeCareAdvisor Study for Caregivers of People Living With Dementia
Status: ACTIVE_NOT_RECRUITING
Conditions: Dementia|Caregiver Burnout|Caregiver Stress Syndrome|Alzheimer Disease|Frontotemporal Dementia|Vascular Dementia|Dementia With Lewy Bodies
Interventions: BEHAVIORAL: Immediate treatment group with High-Intensity Prompts|BEHAVIORAL: Immediate treatment group with Low-Intensity Prompts|BEHAVIORAL: Waitlist Control after three months with High-Intensity Prompts|BEHAVIORAL: Waitlist Control after three months with Low-Intensity Prompts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Letermovir for the Prevention of CMV Infection in HSCT Recipients Based on the Outcome of mNGS
Status: RECRUITING
Conditions: CMV Infection|Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Letermovir Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study Investigating Effects of HTL0009936 on Cognition and BOLD fMRI Signals in Healthy Elderly Subjects
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: HTL0009936|DRUG: HTL0009936 matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Autologous Fat Grafting on Acute Burn Wound Healing
Status: COMPLETED
Conditions: Burns
Interventions: PROCEDURE: autologous fat grafting|DRUG: Topical Cream|PROCEDURE: split thickness skin grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Intensity Regimen vs Myeloablative Regimen for Myeloid Leukemia or Myelodysplastic Syndrome (BMT CTN 0901)
Status: TERMINATED
Conditions: Leukemia, Myelocytic, Acute
Interventions: DRUG: Fludarabine and Busulfan|DRUG: Fludarabine and Melphalan|DRUG: Busulfan and Fludarabine|DRUG: Busulfan and Cyclophosphamide|DRUG: Cyclophosphamide and Total Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Complicated Skin and Skin Structure Infections
Status: COMPLETED
Conditions: Skin Infection|Abscess|Cellulitis
Interventions: DRUG: Meropenem|DRUG: Imipenem-cilastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stimulation Sites and Fatigue Induced by Neuromuscular Electrical Stimulation in Healthy Individuals
Status: ACTIVE_NOT_RECRUITING
Conditions: Fatigue
Interventions: DEVICE: Electric stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effectiveness of Transcranial Magnetic Stimulation of Supplementary Motor Area (SMA) in Patients With Bladder Hypersensitivity and Bladder Pain
Status: UNKNOWN
Conditions: Bladder Hypersensitivity
Interventions: OTHER: Transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Nivolumab and Tumor Infiltrating Lymphocytes (TIL) in Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer|Metastatic Non-small Cell Lung Cancer|Squamous Cell Carcinoma|Advanced NSCLC|Adenosquamous Carcinoma|Adenocarcinomas
Interventions: PROCEDURE: Tumor-infiltrating Lymphocytes (TIL)|DRUG: Nivolumab|DRUG: Cyclophosphamide|DRUG: Fludarabine|OTHER: Tumor-infiltrating Lymphocyte Therapy|DRUG: Interleukin-2 (IL2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Protein Intake During Hemodialysis on Blood Pressure and Arterial Stiffness Indices
Status: UNKNOWN
Conditions: End Stage Renal Disease|Hypotension During Dialysis|Protein Malnutrition|Arterial Sclerosis
Interventions: OTHER: High-protein meals|OTHER: Low- protein meals|OTHER: No meals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Myo-inositol on Human Semen Parameters
Status: COMPLETED
Conditions: Asthenozoospermia|Oligospermia
Interventions: DIETARY_SUPPLEMENT: Myo-inositol normospermic|DIETARY_SUPPLEMENT: Myo-inositol OAT|DIETARY_SUPPLEMENT: Folic Acid normospermic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: 601 Versus Ranibizumab in Patients With Central Retinal Vein Occlusion (CRVO)
Status: UNKNOWN
Conditions: Central Retinal Vein Occlusion
Interventions: DRUG: 601 1.25mg|DRUG: Ranibizuman 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bacterial Colonization With and Without Iodophor-impregnated Adhesive Drapes in Hip Surgery: a Prospective, Randomized Trial
Status: COMPLETED
Conditions: Surgical Wound Infection
Interventions: DEVICE: iodophor-impregnated adhesive drapes|OTHER: No adhesive drapes
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Hypofractionated Regional Nodal Irradiation Clinical Trial for Women With Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Node-positive Breast Cancer|Breast Adenocarcinoma|Invasive Breast Carcinoma|Lobular Breast Carcinoma In Situ
Interventions: RADIATION: External Beam Radiation Therapy|OTHER: Questionnaire Administration|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ursodeoxycholic Acid as Treatment for Polycystic Liver Disease
Status: COMPLETED
Conditions: Polycystic Liver Disease|Polycystic Kidney, Autosomal Dominant
Interventions: DRUG: Ursodeoxycholic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining the Differential Effects of Traditional Float-REST and Dry Float on Subjective and Objective Health Outcomes
Status: ENROLLING_BY_INVITATION
Conditions: Sleep Quality
Interventions: OTHER: Simulated Flotation Therapy|OTHER: Traditional Float-REST Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diet and Omega-3 Intervention Trial on Atherosclerosis
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DIETARY_SUPPLEMENT: No dietary counseling and omega-3 capsules|DIETARY_SUPPLEMENT: Omega-3 capsules and dietary counseling|DIETARY_SUPPLEMENT: Dietary counseling, placebo capsules for omega-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CMC-544 and Allogeneic Transplantation for CD22 Positive-Lymphoid Malignancies
Status: COMPLETED
Conditions: Hematopoietic and Lymphoid Cell Neoplasm
Interventions: PROCEDURE: Allogeneic Bone Marrow Transplantation|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|BIOLOGICAL: Anti-Thymocyte Globulin|DRUG: Bendamustine Hydrochloride|DRUG: Fludarabine Phosphate|BIOLOGICAL: Inotuzumab Ozogamicin|DRUG: Methotrexate|PROCEDURE: Peripheral Blood Stem Cell Transplantation|BIOLOGICAL: Rituximab|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postprandial Blood Cell Transcriptome of Normal Weight and Obese Subjects to 3 Caloric Doses of a High-fat Meal
Status: COMPLETED
Conditions: Obesity|Nutritional Intervention
Interventions: OTHER: high-fat meal A|OTHER: high-fat meal B|OTHER: high-fat meal C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: BOL-DP-o-04 in Patients With Low Back Pain and Sciatica
Status: COMPLETED
Conditions: Low Back Pain|Sciatica
Interventions: DRUG: BOL-DP-o-04 + SCO|DRUG: Placebo + SCO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Upper Extremity Rehabilitation Using Game Rehabilitation System With Functional Electrical Stimulation for Stroke Patients
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: Smart glove system with functional electrical stimulation|DEVICE: Functional electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of an Intravenous Solution of JNJ-39588146 or Placebo in Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: JNJ-39588146 5 ng/kg/min|DRUG: JNJ-39588146 15 ng/kg/min|DRUG: JNJ-39588146 30 ng/kg/min|DRUG: Placebo|DRUG: JNJ-39588146 5, 15, or 30 ng/kg/min
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TAVIS Registry - Trilogy Heart Valve System for Management of Patients With Aortic Valve Disease
Status: NOT_YET_RECRUITING
Conditions: Aortic Valve Stenosis|Aortic Valve Regurgitation|Aortic Valve Stenosis With Insufficiency|Constriction, Pathologic|Aortic Valve Disease|Heart Valve Diseases|Cardiovascular Diseases in Old Age|Ventricular Outflow Obstruction|Aortic Stenosis, Severe
Interventions: DEVICE: Transcatheter Aortic Valve Implantation (TAVI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial to Evaluate the Efficacy and Safety of a Spot Stent System Used in Femoropopliteal Arteries.
Status: RECRUITING
Conditions: Peripheral Vascular Disease (PVD)|Peripheral Arterial Disease (PAD)
Interventions: DEVICE: Spot stent system|DEVICE: Self-expanding peripheral stent system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Evaluation of 16 Weeks' Dietary Supplementation With Iron Bis-glycinate Plus Vitamin C on Cognitive Function, Subjective Mood, Fatigue, Health and Well-being
Status: COMPLETED
Conditions: Cognitive Function and Mood|Non-anaemic Iron Deficiency
Interventions: DIETARY_SUPPLEMENT: Iron Bis-Glycinate Chelate and Vitamin C|DIETARY_SUPPLEMENT: Iron Bis-Glycinate Chelate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy Study of ELND005 as an Adjunctive Maintenance Treatment in Bipolar I Disorder
Status: TERMINATED
Conditions: Bipolar 1 Disorder
Interventions: DRUG: ELND005|DRUG: Lamotrigine|DRUG: Valproic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of SHR-A1811 in HER2-expression Advanced Breast Cancer With Brain Metastases
Status: RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: SHR-A1811|DRUG: Pyrotinib|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MR Fat Quantification and Elastography During a Very Low-calorie-ketogenic Diet (Pronokal Method®) vs a Low Calorie Diet
Status: COMPLETED
Conditions: Liver Fat
Interventions: OTHER: PronoKal Method|OTHER: Low calorie diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Ventilation and Dex in Critically Ill Adults
Status: COMPLETED
Conditions: Respiratory Insufficiency
Interventions: DRUG: Dexmedetomidine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Angong Niuhuang Pill and Acupuncture on PSCI Angong Niuhuang Pill Combined With Supervised Pulse Music Electroacupuncture on Cognitive Impairment After Ischemic Stroke
Status: RECRUITING
Conditions: Post-stroke Cognitive Impairment
Interventions: DRUG: Angong Niuhuang Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cost-benefit Evaluation of a Transdiagnostic Psychological Treatment for Emotional Disorders in Primary Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Emotional Disorder|Depression|Somatoform Disorders|Anxiety Disorders
Interventions: OTHER: Group brief transdiagnostic cognitive-behavioral therapy|OTHER: Individual brief transdiagnostic cognitive-behavioral therapy|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT