pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Debulking and Chemotherapy With or Without Intraperitoneal Chemotherapy to Treat Peritoneal Carcinomatosis
Status: COMPLETED
Conditions: Gastrointestinal Neoplasm
Interventions: PROCEDURE: Cytoreductive surgery|PROCEDURE: Continuous hyperthermic peritoneal perfusion (HIPEC/CHPP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Ilioinguinal Entrapment Syndrome - an Often Overlooked Cause of Chronic Pelvic Pain
Status: COMPLETED
Conditions: Chronic Pelvic Pain
Interventions: DRUG: Amitryptiline, gabapentin|PROCEDURE: Resection of the ilioinguinal nerve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bladder and Bone Effects of Pelvic Radiation Therapy in Childhood Cancer Survivors
Status: RECRUITING
Conditions: Cancer|Childhood Cancer
Interventions: DIAGNOSTIC_TEST: Uroflow testing|DIAGNOSTIC_TEST: Bladder Scan|OTHER: Dysfunctional Voiding Scoring System Survey|DIAGNOSTIC_TEST: DEXA Scan of pelvis and sacral spine|DIAGNOSTIC_TEST: Urine tests for specific biomarkers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Partnering With Food Bank to Provide Tobacco Treatment to Underserved Smokers
Status: RECRUITING
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Smartphone-delivered automated treatment|DRUG: Nicotine patch|BEHAVIORAL: Counceling|DRUG: Nicotine lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vitamin K to Slow Progression of Dyslipidemia and Diabetes Risk (Vita-K 'n' Kids Study II)
Status: UNKNOWN
Conditions: Obesity|Insulin Resistance|Obesity in Diabetes|Nutritional and Metabolic Diseases|Hyperlipidemia|Hyperglycemia|Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Placebo-Control|DIETARY_SUPPLEMENT: Low-Dose Vitamin K2 (menaquinone-7; 45-mcg/d)|DIETARY_SUPPLEMENT: High-Dose Vitamin K2 (menaquinone-7; 90 mcg/d)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ERC1671 to Treat Malignant Gliomas When Given in Combination With GM-CSF, Cyclophosphamide, Bevacizumab and Pembrolizumab
Status: NOT_YET_RECRUITING
Conditions: Glioma, Malignant
Interventions: DRUG: ERC1671|DRUG: GM-CSF|DRUG: Cyclophosphamide|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Individual and Family Self Management Theory Based Epilepsy Education Program's Effectiveness
Status: COMPLETED
Conditions: Self Management|Epilepsy; Seizure|Quality of Life
Interventions: BEHAVIORAL: Epilepsy Education Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Core Stability Exercises on Pain, Muscle Strength, and Muscle Architecture in Tennis Players With Rotator Cuff Lesions
Status: ACTIVE_NOT_RECRUITING
Conditions: Exercise|Muscle Weakness|Rotator Cuff Injuries
Interventions: OTHER: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sildenafil Versus Low Molecular Weight Heparin in Fetal Growth Restriction Treatment
Status: UNKNOWN
Conditions: Fetal Growth Abnormality|Fetal Growth Restriction
Interventions: DRUG: Sildenafil|DRUG: low molecular weight heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Fibrinogen Concentrate and Placenta Acreta Spectrum
Status: COMPLETED
Conditions: Obstetric Anesthesia Problems|Placenta Accreta
Interventions: PROCEDURE: the group without fibrinogen concentrate (GNF) , the group with fibrinogen concentrate (GF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Develop an Algorithm for Predicting the Unfavorable Course of Sepsis in Children Based on a Comprehensive Assessment of Immunological, Biochemical and Molecular Genetic Markers
Status: RECRUITING
Conditions: Sepsis
Interventions: DIAGNOSTIC_TEST: flow cytometry|DIAGNOSTIC_TEST: ELISA|DIAGNOSTIC_TEST: RFLP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Nutritional Intervention for Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathy
Interventions: OTHER: Vegan diet and vitamin B12 supplement|DIETARY_SUPPLEMENT: Vitamin B12 supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Incidence of Macular Edema After Panretinal Photocoagulation (PRPC) Performed in a Single Session Versus Four Sessions in Diabetic Patients.
Status: COMPLETED
Conditions: Diabetes Type 1 or 2 With Diabetic Retinopathy
Interventions: PROCEDURE: PRPC using Pascal laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study Between Postextubation of Preterm Infants Into High-Flow Nasal Cannulae V.S Nasal Continuous Positive Airway Pressure
Status: COMPLETED
Conditions: Neonatal Respiratory Distress
Interventions: DEVICE: High flow nasal cannula vs. Nasal continuous positive airway pressure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of a Physical Activity Programme Using an Intelligent Electric Bike for Health in Healthy Volunteers (PROTOVELIS)
Status: UNKNOWN
Conditions: Physical Activity|Intelligent Electric Bike for Health|Connected Vest
Interventions: DEVICE: Programme of intelligent electric bike for health
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Biomechanical Footwear as a Non-invasive Alternative and Supplement to Total Knee Replacement
Status: RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: AposHealth|PROCEDURE: Total Knee Replacement (TKR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MoCa Test for the Early Detection of Mild Cognitive Impairment During Annual Assessment of Young Adults With Diabetes and in a Control Group Without Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus Type 1|Diabetes Mellitus Type 2|Mild Cognitive Impairment
Interventions: OTHER: MoCa test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Gene Therapy for B-Cell Non-Hodgkin Lymphoma Using CD19 CAR Gene Transduced T Lymphocytes
Status: UNKNOWN
Conditions: Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Interventions: DRUG: Cyclophosphamide or Bendamustine|GENETIC: Dose Level -1|GENETIC: Dose Level 1|GENETIC: Dose Level 2|GENETIC: Dose Level 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telmisartan and Losartan in Hypertensive IGT
Status: COMPLETED
Conditions: Hypertension|Impaired Glucose Tolerance
Interventions: DRUG: Telmisartan 80 mg|DRUG: Losartan 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Smell, Voice and Nasal Swabs as Markers for Neuro-degenerative Disorders
Status: COMPLETED
Conditions: Alzheimer Disease|Neurodegenerative Diseases
Interventions: DIAGNOSTIC_TEST: Cytology and Immunohistochemistry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: AGE SELF CARE: Promoting Healthy Aging Through a Group Visit Program
Status: COMPLETED
Conditions: Frailty|Aging|Frailty Syndrome|Frail Elderly Syndrome
Interventions: BEHAVIORAL: AGE SELF CARE group visit program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Breather on Hospital Stay in Patients With Acquired Pneumonia
Status: COMPLETED
Conditions: Pneumonia Hospital Acquired
Interventions: DEVICE: The Incentive Spirometer|DEVICE: The breather respiratory muscle training device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Demonstrate the Efficacy of Cangrelor
Status: TERMINATED
Conditions: Myocardial Infarction (MI)|Acute Coronary Syndromes (ACS)
Interventions: DRUG: Cangrelor (P2Y12 inhibitor)|DRUG: clopidogrel (oral P2Y12 inhibitor)|DRUG: Placebo bolus & placebo infusion|DRUG: Placebo capsules - end of infusion|DRUG: Placebo capsules - as soon as possible after randomization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SAD/MAD Study of a New Formulation of Nebulised RPL554 in Healthy Subjects and COPD Subjects
Status: COMPLETED
Conditions: Inflammatory Disorder of the Respiratory Tract|Chronic Obstructive Pulmonary Disorder
Interventions: DRUG: RPL554|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effect of Perioperative Caloric Restriction Program on Perioperative Outcomes in Patients With Obesity and Endometrial Cancer
Status: TERMINATED
Conditions: Obese|Endometrial Cancer
Interventions: OTHER: Perioperative Caloric Restriction Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Locally Advanced Pancreatic Cancer After Systemic Therapy: Ablative MR-guided Radiotherapy
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Pancreatic Adenocarcinoma
Interventions: RADIATION: MR guided radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CST-103 Co-administered With CST-107 in Subjects With Parkinson's Disease Having Freezing of Gait (CLIN-012)
Status: WITHDRAWN
Conditions: Freezing of Gait Symptoms in Parkinson's Disease
Interventions: DRUG: CST-103, CST-107, matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Inhaled Levosimendan
Status: RECRUITING
Conditions: Left Ventricular Dysfunction
Interventions: DRUG: Levosimendan 2.5 milligram/milliliter Injectable Solutiondose Inhaled|DRUG: Levosimendan 2.5 milligram/milliliter Injectable Solutiondose Intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tenofovir Disoproxil Fumarate in the Treatment of Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DRUG: Tenofovir Disoproxil Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Warmth and Transcutaneous Electrical Nerve Stimulation (TENS) in Improving Cognitive Functions in People With Dementia
Status: RECRUITING
Conditions: Dementia
Interventions: DEVICE: Warmth + TENS|DEVICE: Warmth + placebo-TENS|DEVICE: TENS|DEVICE: Warmth only|DEVICE: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cell Infusion in Haploidentical Hematopoietic Stem Cell Transplantation in Patients With Hematological Malignancies
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplantation
Interventions: BIOLOGICAL: mesenchymal stem cells|DRUG: cyclophosphamide administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: E. Max Laminate Veneers With and Without Using Galla Chinnesis as Natural Cross Linking and Remineralizing Agent
Status: UNKNOWN
Conditions: Amelogenesis Imperfecta
Interventions: OTHER: Galla Chinnesis|OTHER: Conventional Bonding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CPAP Effect on Albuminuria in Patients With Diabetic Nephropathy and Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Diabetic Nephropathy|Sleep Apnea
Interventions: DEVICE: Continuous positive airway pressure|DRUG: Pharmacological treatment|OTHER: Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation in Episodic and Chronic Tension-type Headache
Status: RECRUITING
Conditions: Chronic Tension-Type Headache
Interventions: DIETARY_SUPPLEMENT: Vitamin D|OTHER: Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Iron and Muscular Damage: FEmale Metabolism and Menstrual Cycle During Exercise
Status: COMPLETED
Conditions: Iron-deficiency|Inflammation|Exercise Induced Iron-deficiency|Exercise Induced Muscle Damage|Regulation of Sex Hormones on Hepcidin|Regulation of Sex Hormones on Muscle Damage|Iron Metabolism Disorders
Interventions: PROCEDURE: Interval running protocol / eccentric-based resistance exercise protocol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: COVID-19: SARS-CoV-2-CZ-PREVAL-II Study
Status: COMPLETED
Conditions: COVID-19|SARS-CoV-2 Infection
Interventions: DIAGNOSTIC_TEST: Quantitative analysis of SARS-CoV-2 antibodies|DIAGNOSTIC_TEST: Cellular immunity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MER3101: MAS-1 Adjuvanted Antigen-specific Immunotherapeutic for Prevention and Treatment of Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: MAS-1 adjuvanted Insulin B-chain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IV Clinical Trial of an Influenza Split Vaccine Anflu
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: seasonal split influenza vaccine|BIOLOGICAL: seasonal split influenza vaccine|BIOLOGICAL: seasonal split influenza vaccine|BIOLOGICAL: seasonal split influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Effects of Using Cooling Pillowcases, on the Symptoms of Hot Flushes, Sleep and Life Quality
Status: RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: Cooling Pillowcases
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Interventional Bioremediation of Microbiota in Metabolic Syndrome
Status: TERMINATED
Conditions: Pre-Diabetes
Interventions: DRUG: Vancomycin|OTHER: Placebo|DRUG: Neomycin|DRUG: Clindamycin|PROCEDURE: Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Tantum Verde® on Recovery Following Tonsillectomy
Status: COMPLETED
Conditions: Tonsillectomy|Adenoidectomy
Interventions: DRUG: Tantum Verde® mouthwash|OTHER: Placebo mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Impact of Serial Remote Ischemic Conditioning on Dynamic Cerebral Autoregulation in Healthy Adults
Status: COMPLETED
Conditions: Remote Ischemic Conditioning
Interventions: DEVICE: BB-RIC-D1/LAPUL Medical Devices Co, Ltd, China|PROCEDURE: Intravenous blood collection|DEVICE: dCA measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Tolerability of Alprostadil Liposome for Injection in Healthy Adult Volunteers
Status: UNKNOWN
Conditions: Lower Extremity Arterial Occlusive Diseases
Interventions: DRUG: Alprostadil Liposome for Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Patients With Moderate Asthma to Compare Pharmacokinetics and Pharmacodynamic Effects of Fluticasone Propionate and Salmeterol Delivered Via the ROTAHALER® Inhaler Relative to the DISKUS® Inhaler
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: Fluticasone Propionate/Salmeterol Xinafoate DISKUS|DRUG: Placebo to Match DISKUS|DRUG: Fluticasone Propionate/Salmeterol Xinafoate ROTACAPS|DRUG: Placebo to Match ROTACAPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tissue Oxygenation of the Tibial Anterior Muscle After Clamping of the Femoral Artery
Status: COMPLETED
Conditions: Tissue Oxygen Saturation
Interventions: PROCEDURE: Sevoflurane preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Innovative Physiotherapy and Coordination of Care for People With MS: a RCT and a Qualitative Study
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: GroupCoreSIT|BEHAVIORAL: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Age-related Macular Degeneration of Atrophic Type Treated With Umbilical Cord Blood Enriched With Platelet Plasma.
Status: RECRUITING
Conditions: Dry Age-related Macular Degeneration
Interventions: PROCEDURE: Intravitreal injection of CB-PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Consuming Palm Oil With Different Macronutrient Intakes on Blood Lipids
Status: COMPLETED
Conditions: Cardiovascular Diseases|Inflammation
Interventions: OTHER: Canola Oil|OTHER: Palm Oil|OTHER: Butter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Laryngeal Mask Airway on Image Quality n Pediatric Patients Undergoing Magnetic Resonant Imaging
Status: COMPLETED
Conditions: Airway Obstruction
Interventions: DEVICE: guedel airway|DEVICE: supraglottic airway|DRUG: propofol bolus and then anesthesia sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Febuxostat 80 mg Tablets Relative to Feburic® 80 mg Tablets
Status: NOT_YET_RECRUITING
Conditions: Healthy Subjects
Interventions: DRUG: Febuxostat-Test product|DRUG: Febuxostat-Reference product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Sage Tablets Compared to Placebo in Menopausal Patients With Hot Flushes and Sweating
Status: TERMINATED
Conditions: Menopausal Hot Flushes
Interventions: DRUG: Sage extract, 3400 mg , DER 1:17
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Applying Pharmacogenetic Algorithms to Individualize Dosing of Warfarin
Status: COMPLETED
Conditions: Thromboembolism
Interventions: GENETIC: IWPC adapted genotype-guided dosing algorithm for warfarin|GENETIC: Modified IWPC genetic-guided warfarin dosing algorithm|OTHER: Standard of care treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transoral Robotic Surgery or Standard Surgery in Treating Patients With Benign or Malignant Tumors of the Larynx and Pharynx
Status: COMPLETED
Conditions: Head and Neck Cancer|Perioperative/Postoperative Complications|Precancerous Condition
Interventions: PROCEDURE: assessment of therapy complications|PROCEDURE: diagnostic endoscopic surgery|PROCEDURE: quality-of-life assessment|PROCEDURE: therapeutic conventional surgery|PROCEDURE: therapeutic endoscopic surgery|PROCEDURE: transoral robotic surgery|PROCEDURE: video-assisted surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Levocetirizine + Capecitabine + Bevacizumab for Patients With Refractory Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: Bevacizumab|DRUG: Capecitabine|DRUG: Levocetirizine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neratinib and Trastuzumab Biosimilar in Patients With HER2 Mutated Advanced Solid Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Cancer|HER2 Gene Mutation
Interventions: DRUG: Neratinib Maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UroCAD Assay Combined With Computed Tomography Urography and Urine Cytology for UTUC Diagnosis.
Status: UNKNOWN
Conditions: Urothelial Carcinoma|Diagnoses Disease|Ureter Cancer|IMAGE|Cytology
Interventions: DIAGNOSTIC_TEST: UroCAD assay, CTU examination and urine cytology
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy and Safety of Oral Oxcarbazepine 300-1200 mg/Day as Adjuvant Therapy in the Treatment of Adolescents With Impulsivity and Aggressive Behavior in Conduct Disorder This Study is Not Being Conducted in the United States.
Status: COMPLETED
Conditions: Conduct Disorder
Interventions: DRUG: Oxcarbazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Therapeutic Efficacy of Ductoscopic Papilloma Extraction in Patients With Pathologic Nipple Discharge
Status: TERMINATED
Conditions: Breast Discharge Infected|Intraductal Papilloma of Breast
Interventions: DEVICE: Ductoscopic papillectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn More About How Well Elinzanetant Works and How Safe it is for the Treatment of Vasomotor Symptoms (Hot Flashes) That Are Caused by Hormonal Changes Over 26 Weeks in Women Who Have Been Through the Menopause
Status: COMPLETED
Conditions: Vasomotor Symptoms Associated With Menopause|Hot Flashes
Interventions: DRUG: Elinzanetant (BAY3427080)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Goldenseal-drug Interactions Using a Probe Drug Cocktail Approach
Status: COMPLETED
Conditions: Interaction Drug Food
Interventions: DIETARY_SUPPLEMENT: goldenseal|DRUG: Metformin|DRUG: Furosemide|DRUG: Midazolam oral solution|DRUG: Rosuvastatin Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate R3R01 in Patients With Alport Syndrome and Patients With Focal Segmental Glomerulosclerosis
Status: RECRUITING
Conditions: Alport Syndrome|Focal Segmental Glomerulosclerosis
Interventions: DRUG: R3R01
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dietary Nitrate From Vegetable/Fruit Juice on Cerebral Blood Flow Parameters
Status: COMPLETED
Conditions: Cerebrovascular Circulation|Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: Vegetable/fruit juice|DIETARY_SUPPLEMENT: Placebo juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of Nivolumab in Combination With Ipilimumab in Subjects With Previously Untreated Metastatic Uveal Melanoma
Status: COMPLETED
Conditions: Uveal Melanoma
Interventions: DRUG: ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefit of Adding Chemotherapy And/Or Modification of Radiotherapy Schedule for Advance Nasopharyngeal Carcinoma (T3-4N0-1M0)
Status: TERMINATED
Conditions: Nasopharyngeal Neoplasms|Carcinoma, Squamous Cell
Interventions: PROCEDURE: Conventional RT|PROCEDURE: Accelerated RT|DRUG: Cisplatin|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Access to EyeGlasses for School-aged Children
Status: NOT_YET_RECRUITING
Conditions: Myopia|Amblyopia|Hyperopia|Refractive Errors
Interventions: OTHER: Fitz Frames 3-D Printed Glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Weighted and Elastic Resistance Training of Gluteus Maximus in Sacroiliac Joint Dysfunction
Status: COMPLETED
Conditions: Sacroiliac Disorder
Interventions: OTHER: Group A: Elastic resisted training for Gluteus Maximus strength|OTHER: Group B: Weight resisted training for Gluteus Maximus strength
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Specific Thoracic Spine Mobilizations on Muscle Activity in a Healthy Volunteer Population
Status: RECRUITING
Conditions: Musculoskeletal Manipulations|Range of Motion|Muscle Strength|Peripheral Joints in Upper Quarters
Interventions: OTHER: mobilization|OTHER: no effect
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Titanium vs. PEEK Fusion Devices in 1 Level TLIF
Status: NOT_YET_RECRUITING
Conditions: Spine Fusion|Lumbar Spondylolisthesis|Lumbar Stenosis
Interventions: DEVICE: Titanium Fusion Device|DEVICE: PEEK Fusion Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Assess the Cutaneous Irritation and Sensitization Potential of a Cosmetic Facial Product Using a Human Repeat Insult Patch Test (HRIPT) in Healthy Participants
Status: COMPLETED
Conditions: Skin Care
Interventions: OTHER: Facial micellar cleanser|OTHER: Saline Solution: Sodium Chloride (NaCl; 0.9%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: FeelFit: High-intensity Interval Training to Improve Self-reported Physical Fitness in Brain Tumor Patients
Status: RECRUITING
Conditions: Brain Tumor, Primary|Exercise
Interventions: OTHER: High-Intensity Interval Training (HIIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Antiplatelet Therapies in Patients With Depression and Coronary Disease
Status: RECRUITING
Conditions: Coronary Artery Disease|Depression
Interventions: OTHER: standard Aspirin (ASA) + clopidogrel (CLP) therapy|OTHER: standard Aspirin (ASA) + Ticagrelor (TCG) or Prasugrel (PSG) therapy|OTHER: standard ASA therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Crohn's Complex Perianal Fistulas With Tissue Transplantation by Local Injection of Micro-fragmented Autologous Adipose Tissue.
Status: ACTIVE_NOT_RECRUITING
Conditions: Crohn Disease
Interventions: DEVICE: Lipogems
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetic (PK) Study of DHES0815A in Participants With Human Epidermal Growth Factor Receptor (HER)2-Positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: DHES0815A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 24-Week Efficacy and Safety Study to Assess Budesonide and Formoterol Fumarate Metered Dose Inhaler in Adult and Adolescent Participants With Inadequately Controlled Asthma (VATHOS)
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: BFF MDI 320/9.6 μg|DRUG: BFF MDI 160/9.6 μg|DRUG: BD MDI 320 μg|DRUG: Open-label Symbicort TBH 320/9 μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Connective Tissue Massage in Patients With Migraine
Status: COMPLETED
Conditions: Migraine With Aura|Migraine|Migraine Without Aura|Connective Tissue Diseases
Interventions: OTHER: Connective Tissue Massage|OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypercapnia and Its Association With Long-term Respiratory Morbidities in Premature Infants With Chronic Lung Disease
Status: WITHDRAWN
Conditions: Bronchopulmonary Dysplasia
Interventions: DEVICE: Massimo Root Monitoring System|DEVICE: ISA-Infrared Sidestream Gas Analyzer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Smoking Cessation in Cancer Treatment
Status: UNKNOWN
Conditions: Smoking Cessation|Motivation
Interventions: BEHAVIORAL: Structured smoking cessation counselling based on motivational interviewing (MI) and adapted for the cancer setting eventually combined with provision of smoking cessation medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ball and Socket Versus Locator Attachment Retained Implant Overdentures
Status: UNKNOWN
Conditions: Complete Edentulism
Interventions: DEVICE: Locator Attachment (positioner)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics and Corticosteroids for Treating Periodic Fever, Aphthous Stomatitis, Pharyngitis, Cervical Adenitis (PFAPA)
Status: WITHDRAWN
Conditions: Periodic Fever|Aphthous Stomatitis|Pharyngitis|Cervical Adenitis
Interventions: BIOLOGICAL: Lactobacillus acidophilus and Bifidobacterium lactis|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exploration of Personalized Biomarkers During Neoadjuvant Radiation Therapy for Spinal and Sacral Chordoma
Status: RECRUITING
Conditions: Chordoma of Spine|Chordoma of Skull Base|Chordoma of Sacrum
Interventions: DIAGNOSTIC_TEST: ctDNA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acupuncture for Symptom Control in Hematopoietic Stem Cell Transplantation Patients
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: PROCEDURE: Acupuncture|PROCEDURE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Trials of Gastric Bypass Surgery in Patients With Type II Diabetes Mellitus
Status: UNKNOWN
Conditions: Type II Diabetes Mellitus
Interventions: PROCEDURE: gastric bypass|PROCEDURE: sleeve gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Fecal Microbiota Transplantation (FMT) in Reducing Recurrence of Colorectal Adenoma (CRA)
Status: RECRUITING
Conditions: Fecal Microbiota Transplantation|Colorectal Adenoma|Gastrointestinal Microbiome
Interventions: PROCEDURE: fecal microbiota transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Salivary SARS-CoV-2 Load of Covid-19 Patients After Oral Antimicrobial Solutions and Dentifrices
Status: COMPLETED
Conditions: Corona Virus Infection
Interventions: OTHER: Colgate Periogard® mouthwash|OTHER: Colgate Peroxyl® mouthwash|OTHER: Colgate Total® Mouthwash|OTHER: Toothpaste with sodium monofluorophosphate|OTHER: Toothpaste with sodium fluoride and zinc|OTHER: Toothpaste with tin fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TelemEdiciNe-bAsed Cognitive TherapY for Migraines
Status: COMPLETED
Conditions: Migraine Headache
Interventions: BEHAVIORAL: TENACITY Telehealth Cognitive Behavioral Therapy for Migraine|BEHAVIORAL: Behavioral Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Metformin Versus Vildagliptin for Diabetic Hypertensive Patients
Status: COMPLETED
Conditions: Reducing the Elevated Blood Pressure for Diabetic Hypertensive Patients
Interventions: DRUG: Metformin Pill|DRUG: Vildagliptin 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Emricasan, a Caspase Inhibitor, for Evaluation in Subjects With Non-Alcoholic Steatohepatitis (NASH) Fibrosis
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis|Fibrosis|Liver Diseases
Interventions: DRUG: Emricasan (5 mg)|DRUG: Emricasan (50 mg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Comparison of Two Different Techniques of Uterine Cesarean Incision Closure
Status: COMPLETED
Conditions: Cesarean Section; Complications|Placenta Previa|Placenta Accreta
Interventions: PROCEDURE: Purse string closure technique|PROCEDURE: Continuously locked closure technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Dexamethasone in Pediatric Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Surgery|Congenital Heart Defects|Cardiopulmonary Bypass
Interventions: DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Perampanel (E2007) on Synaptic Dopamine in Mild-moderate PD Patients: A Pilot Study With [^123I]-IBZM SPECT
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: DRUG: perampanel|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: L-cysteine Prevents Stomach Exposure to Carcinogenic Acetaldehyde
Status: COMPLETED
Conditions: Gastritis, Atrophic
Interventions: DIETARY_SUPPLEMENT: Slow-release L-cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Levomilnacipran ER (F2695 SR) in Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Levomilnacipran ER|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of CG 8020 and CG 2505 in Patients With Nonresectable or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer|Nonresectable Pancreatic Cancer
Interventions: BIOLOGICAL: CG 8020 and CG 2505
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of SPR001 in Adults With Classic Congenital Adrenal Hyperplasia
Status: COMPLETED
Conditions: Congenital Adrenal Hyperplasia|CAH - Congenital Adrenal Hyperplasia
Interventions: DRUG: SPR001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of YPEG-Filgrastim in Chemotherapy Patients
Status: COMPLETED
Conditions: Chemotherapy Patients
Interventions: DRUG: YPEG-Filgrastim|DRUG: YPEG-Filgrastim|DRUG: YPEG-Filgrastim|DRUG: YPEG-Filgrastim|DRUG: YPEG-Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Study to Compare the Efficacy and Safety of Two CC-5013 Dose Regimens in Subjects With Metastatic Malignant Melanoma
Status: COMPLETED
Conditions: Melanoma|Neoplasm Metastasis
Interventions: DRUG: CC 5013
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Multidrug Resistant Micro-organism Carriage in Patients Undergoing an ERCP in Four Different Countries
Status: RECRUITING
Conditions: Drug Resistance, Multiple, Bacterial|Cholangiopancreatography, Endoscopic Retrograde
Interventions: DIAGNOSTIC_TEST: Multidrug-Resistant Organisms (MDRO) testing through rectal and oral/nasal swabs|DIAGNOSTIC_TEST: MDRO-testing duodenal aspirate|DIAGNOSTIC_TEST: Microbiome through rectal swab|DIAGNOSTIC_TEST: Microbiome testing duodenal aspirate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Imatinib Standard Dose With Imatinib High Dose Induction in Pretreated Chronic Myeloid Leukemia (CML) Patients in Chronic Phase
Status: UNKNOWN
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects
Status: RECRUITING
Conditions: Retinal Dystrophy|PRPF31 Mutationassociated Retinal Dystrophy|RP11
Interventions: DRUG: VP-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sevoflurane in COVID-19 ARDS (SevCov)
Status: COMPLETED
Conditions: ARDS, Human|Coronavirus
Interventions: DRUG: Sevoflurane|DRUG: Intravenous drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-surgical Periodontal Therapy and Myo-inositol in Polycystic Ovary Syndrome Women Having Chronic Periodontitis
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome|Periodontitis|Insulin Resistance
Interventions: PROCEDURE: scaling and root planing , Myo-inositol|DRUG: Myo-inositol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Transcriptomic Study of Thai Patients With Atopic Dermatitis by Tape Strips
Status: NOT_YET_RECRUITING
Conditions: Atopic Dermatitis
Interventions: GENETIC: Tape strips
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study To Investigate The Absorption, Distribution, Metabolism, And Excretion Of [14c]PF-06463922 In Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [14C] PF-06463922
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Relative Bioavailibilty for Pediatric Powder for Suspension (PfOS) Formulation and Food Effect
Status: COMPLETED
Conditions: Purpura, Thrombocytopaenic, Idiopathic
Interventions: DRUG: Eltrombopag|DRUG: Eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Multitarget Therapy for Idiopathic Membranous Nephropathy
Status: COMPLETED
Conditions: Efficacy
Interventions: DRUG: Prednisone, ciclosporin and mycophenolate mofetil|DRUG: Ponticelli Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of 2 Schedules of ALVAC-HIV vCP1452 in Chronically HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infection
Interventions: BIOLOGICAL: one injection of vCP1452 at W0, W4, W8 and W20|BIOLOGICAL: one injection of vCP1452 at W4, W8 and W20|BIOLOGICAL: one injection of placebo at W0, W4, W8, W20 or at W4, W8,W20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous vs. Topical Tranexamic Acid in Revision THA (VITALITY-X)
Status: UNKNOWN
Conditions: Tranexamic Acid|Blood Loss, Surgical|Arthroplasty, Replacement, Hip
Interventions: DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PoC Study of OBE022 in Threatened Preterm Labour
Status: UNKNOWN
Conditions: Preterm Labor
Interventions: DRUG: OBE022|DRUG: Placebos|DRUG: Atosiban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Binge Eating Disorder Treatments
Status: COMPLETED
Conditions: Eating Disorders
Interventions: BEHAVIORAL: Interpersonal Therapy|BEHAVIORAL: Behavioral Weight Loss Treatment|BEHAVIORAL: Guided Self Help
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Lidocaine 5% Patch Versus Placebo in Patients With Osteoarthritis Pain of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Lidoderm|DRUG: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AZD1419 Ph2a Study
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: AZD1419|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter LAser VA Registry of Percutaneous Coronary Interventions (LAVA)
Status: UNKNOWN
Conditions: Arteriosclerosis|Coronary Artery Disease|Laser-assisted Percutaneous Coronary Interventions
Interventions: PROCEDURE: Laser-assisted percutaneous coronary interventions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Comparing Pemetrexed Plus Best Supportive Care Versus Best Supportive Care Alone in the Treatment of Mesothelioma
Status: COMPLETED
Conditions: Mesothelioma
Interventions: DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-session Growth Mindset Intervention for Children and Young People With Mental Health Difficulties
Status: SUSPENDED
Conditions: Anxiety|Anxiety Disorders|Depression|Low Mood
Interventions: BEHAVIORAL: Growth Mindset Online Single-Session Intervention|BEHAVIORAL: Supportive Therapy Online Single-Session Intervention (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dietetic Versus Topical Steroids for Pediatric Eosinophilic Esophagitis
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: Budesonide|DRUG: Fluticasone|BEHAVIORAL: six-foods elimination diet|DRUG: Oral Viscous Budesonide (OVB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Salvianolate Injection on Myocardial Microcirculation in Patients With Acute STEMI After Primary PCI
Status: UNKNOWN
Conditions: STEMI - ST Elevation Myocardial Infarction
Interventions: DRUG: Normal saline|DRUG: Salvianolate injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT