pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of Physician and Patient Knowledge of Safety and Safe Use Information for Aflibercept
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: BEHAVIORAL: Aflibercept (Eylea, VEGF Trap-Eye, BAY86-5321)|BEHAVIORAL: Aflibercept (Eylea, VEGF Trap-Eye, BAY86-5321)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Radio-frequency Induced Heat (RFH)Therapy in Treatment of Cutaneous Leishmaniasis in India
Status: COMPLETED
Conditions: Cutaneous Leishmaniasis
Interventions: OTHER: RFH therapy|DRUG: Sodium stibogluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Randomized Double-Blind Placebo-Controlled Study of NRP104 in Children Aged 6-12 With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: NRP104|DRUG: NRP104|DRUG: NRp104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rating Pelvic Organs Prolapse in Women According to the POPQ Method Before and After Emptying the Urinary Bladder
Status: UNKNOWN
Conditions: Patients With Pelvic Organs Prolapse
Interventions: DEVICE: Medtronic-Dantec Urodynamic System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: a Multicentre Phase III Study of Risk-based Treatment Intensification With Hyperfractionated Radiotherapy in Head and Neck Cancer Patients
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: RADIATION: Hyperfractionated radiotherpy|RADIATION: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Ascertain if Prolonged Release Tacrolimus (FK506E - MR4) is Safe and Effective When Used in the Long Term and in Combination With Other Immunosuppressive Drugs in Patients Who Have Received a Transplant
Status: COMPLETED
Conditions: Heart Transplantation|Liver Transplantation|Kidney Transplantation
Interventions: DRUG: FK506E
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intake of Omega 3 in Morbidly Obese Patients
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: DIETARY_SUPPLEMENT: Omega 3 intake, morbid obesity|DIETARY_SUPPLEMENT: Placebo Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Salivary Cortisol Measurement in Corticotrope Deficiency Substitution With Hydrocortisone.
Status: COMPLETED
Conditions: Adrenal Insufficiency
Interventions: DRUG: Hydrocortisone (capsule)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Statins for Prevention of Contrast Induced Nephropathy
Status: COMPLETED
Conditions: Contrast Induced Nephropathy
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Characterization of NK Cells Under First Line Advanced Therapy Either as Curative Therapy for Metastatic Melanoma or as Adjuvant Therapy for High-risk of Recurrence
Status: UNKNOWN
Conditions: Melanoma
Interventions: OTHER: Blood samples|OTHER: Skin biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Hepatitis B Vaccination in Infants
Status: COMPLETED
Conditions: Meningococcal Disease|Pneumococcal Disease|Haemophilus Influenzae Serotype b Disease|Diphtheria, Tetanus and Pertussis|Hepatitis b
Interventions: BIOLOGICAL: Menjugate|BIOLOGICAL: Menitorix|BIOLOGICAL: NeisVac-C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of GSK3359609 and Pembrolizumab in Programmed Death Receptor 1-ligand 1 (PD-L1) Positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
Status: TERMINATED
Conditions: Neoplasms, Head and Neck
Interventions: DRUG: feladilimab|DRUG: Pembrolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The REFLECT Trial: Cerebral Protection to Reduce Cerebral Embolic Lesions After Transcatheter Aortic Valve Implantation
Status: COMPLETED
Conditions: Symptomatic Aortic Stenosis
Interventions: DEVICE: Embolic Protection Device|PROCEDURE: Transcatheter aortic valve implantation (TAVI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: the Effects of Individualized Tai Chi Training on Balance Control in Elderly
Status: COMPLETED
Conditions: Tai Ji
Interventions: OTHER: individualized Tai Chi|OTHER: Entire Tai Chi|OTHER: home-based program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Chlorhexidine Gluconate (CHG) Cloth on Healthy Subjects
Status: COMPLETED
Conditions: Surgery
Interventions: DRUG: Chlorhexidine Gluconate|OTHER: Vehicle|DRUG: DynaHex-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Trial of Brentuximab Vedotin for Refractory Chronic Graft-vs.-Host Disease (GVHD)
Status: TERMINATED
Conditions: Graft-vs-Host Disease|GVHD
Interventions: DRUG: Brentuximab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atrophic Age-related Macular Degeneration (AMD) Treated With Intravitreal Injections of Umbilical Cord Blood Platelet-rich Plasma (CB-PRP): a Pilot Study
Status: RECRUITING
Conditions: Dry Age-related Macular Degeneration
Interventions: PROCEDURE: Intravitreal injection of CB-PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Versus Best Supportive Care in Egyptian Hepatocellular Carcinoma Patients.
Status: COMPLETED
Conditions: HCC
Interventions: DRUG: Sorafenib|DRUG: Best Supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Therapy Versus Open Radical Hysterectomy for Management of Early Stage Cervical Cancer
Status: NOT_YET_RECRUITING
Conditions: Cancer of Cervix|Laparoscopic Surgery
Interventions: PROCEDURE: radical hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epigenetic Modulation of the immunE Response in GastrointEstinal Cancers (EMERGE)
Status: UNKNOWN
Conditions: Cancer|GI Cancer
Interventions: DRUG: Domatinostat|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Focused Ultrasound Modulation of the Globus Pallidus Interna in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Schizophrenia Schizoaffective
Interventions: DEVICE: PLIFUS|DEVICE: Sham PLIFUS|DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Study of H01_04TP to Evaluate the Booster Response Induced by Vi-CRM197 in Adults
Status: COMPLETED
Conditions: Typhoid Fever
Interventions: BIOLOGICAL: NVGH Vi-CRM197
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Efficacy of Carbamazepine in Therapy of Patients With Moderate Persistent and Severe Bronchial Asthma
Status: COMPLETED
Conditions: Bronchial Asthma
Interventions: DRUG: Carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Effectiveness of the REAL INTELLIGENCE™ CORI™ in Total Knee Arthroplasty (TKA) Procedure
Status: RECRUITING
Conditions: Arthroplasty|Replacement|Knee
Interventions: DEVICE: CORI Robotics|PROCEDURE: Conventional Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics and Pharmacodynamics of BIRT 1696 BS in Healthy Human Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIRT 1696 BS|DRUG: Placebo|OTHER: Grapefruit juice (GFJ)|OTHER: High fat meal (HFM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Splints in Pregnant Women With Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|Pregnancy Related|Splints
Interventions: OTHER: Volar supported splint|OTHER: elastic splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Metformin Active Surveillance Trial (MAST) Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Efficacy of Internal and External Perturbation Exercises on Functional Parameters in Stroke Rehabilitation
Status: UNKNOWN
Conditions: Stroke
Interventions: OTHER: Internal Perturbation|OTHER: Eksternal Perturbation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intra-tumor Injection of Oncolytic Viruses H101 Combined With or Without Radiotherapy in Refractory/Recurrent Gynecological Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Genital Neoplasms, Female
Interventions: DRUG: H101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Validation Study of Relationships Among Genomic Gene Expression Profile, Prognosis and Prediction of Adjuvant Chemotherapy Benefit With Capecitabine and Oxaliplatin in Gastric Cancer Stage II and III (6th AJCC) Patients After D2 Surgery (CLASSIC)
Status: COMPLETED
Conditions: Stage II-III Gastric Cancer
Interventions: GENETIC: nProfiler I Stomach Cancer Assay Kit
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chronic-disease Self-management Program in Patients Living With Long-COVID in Puerto Rico
Status: RECRUITING
Conditions: Long Covid19
Interventions: OTHER: "Tomando control de su salud" (Spanish Chronic Disease Self-Management)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CAMBRA - PBRN Caries Management By Risk Assessment In A Practice-Based Research Network
Status: COMPLETED
Conditions: Dental Caries
Interventions: OTHER: Caries prevention active intervention|OTHER: control treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating The Safety, Tolerability And Brain Function Of 2 Doses Of PF-0254920 In Subjects With Early Huntington's Disease
Status: COMPLETED
Conditions: Huntington's Disease
Interventions: DRUG: PF-02545920|DRUG: Placebo|DRUG: PF-02545920|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Comparing Taliderm™ Dressing Versus Standard of Care for Open Incision and Drainage of Wounds
Status: COMPLETED
Conditions: Wounds
Interventions: OTHER: Taliderm™|OTHER: Taliderm™|OTHER: standard wet to dry dressing with gauze
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of K-312 in Healthy Subjects
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: K-312 10 mg QD|DRUG: K-312 25 mg QD|DRUG: K-312 50 mg QD|DRUG: K-312 100 mg QD|DRUG: K-312 200 mg QD|DRUG: K-312 400 mg QD|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of Maintenance SUO11248 Versus Placebo Post Chemotherapy for Patients With Advanced Urothelial Carcinoma
Status: TERMINATED
Conditions: Bladder Cancer
Interventions: DRUG: SUTENT|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Descriptive Study on the Evaluation of Well-being in Relation to Diet and Nutrition and Comparison Between Three Care Units in the Dijon University Hospital Centre
Status: COMPLETED
Conditions: Hospitalization in Cardiology, Orthopaedic Surgery or Endocrinology Departments
Interventions: OTHER: Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chat-based Support for Preventing Smoking Relapse
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Chat-based instant messaging support|BEHAVIORAL: SMS message support|BEHAVIORAL: Self-help booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of AI Assisted Follow-up Strategy on Secondary Prevention in CABG Patients
Status: UNKNOWN
Conditions: Coronary Heart Disease|Artificial Intelligence|Sleep Apnea
Interventions: OTHER: artificial intelligence assisted follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Stem Cell Transplantation for Patients With Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Myeloma
Interventions: DRUG: G-CSF|DRUG: Plerixafor|PROCEDURE: Apheresis|DRUG: Melphalan|PROCEDURE: Stem cell re-infusion|DRUG: Basiliximab|DEVICE: CliniMACS CD25 microbeads and cell sorter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Serum Trefoil Factor 3 in Patients With Gingivitis and Periodontitis After Scaling and Root Planing
Status: COMPLETED
Conditions: Gingivitis and Periodontal Diseases
Interventions: PROCEDURE: Scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SGLT2 Inhibitor Adjunctive Therapy to Closed Loop Control in Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: COMBINATION_PRODUCT: Empagliflozin + Control-IQ x 4 wks then Basal-IQ x 2 wks|COMBINATION_PRODUCT: Empagliflozin + Basal-IQ x 2 wks then Control-IQ x 4 wks|DEVICE: No Empagliflozin + Control-IQ x 4 wks then Basal-IQ x 2 wks|DEVICE: No Empagliflozin + Basal-IQ x 2 wks then Control-IQ x 4 wks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Exercise Training on Left Ventricular Function in Patients Post Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction|Heart Failure|Coronary Artery Disease
Interventions: OTHER: Secondary prevention and cardiac rehabilitation clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Safety and Efficacy of Detaenial Sigmoid Neobladder and Ileal Neobladder
Status: RECRUITING
Conditions: Bladder Cancer|Urinary Diversion
Interventions: PROCEDURE: sigmoid|PROCEDURE: ileal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance Therapy With Ceplene® (Histamine) and IL-2 on Immune Response and MRD in Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: histamine dihydrochloride and IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Study on Fosinopril and/or Losartan in Patients With Chronic Kidney Disease Stage 3
Status: UNKNOWN
Conditions: Chronic Kidney Insufficiency|Angiotensin-Converting Enzyme Inhibitors|Angiotensin II Type 1 Receptor Blockers|Proteinuria
Interventions: DRUG: Fosinopril and Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided TAP Block Vs Local Wound Infiltration for Analgesia After Cesarean Section.
Status: UNKNOWN
Conditions: Postoperative Pain Control
Interventions: PROCEDURE: Ultrasound-guided transversus abdominis plane (TAP) block 0.25% bupivacaine.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Amlodipine on Anti-platelet Drug Effect in Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Ischemic Heart Disease
Interventions: DRUG: Amlodipine|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2409021 in Participants With Type 2 Diabetes Mellitus
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY2409021|DRUG: Sitagliptin|DRUG: Placebo|DRUG: Metformin|DRUG: Sulfonylurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Fruquintinib With Sintilimab as First-line Therapy in Gastric Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Stomach Neoplasms
Interventions: DRUG: Fruquintinib|DRUG: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: KEYMAKER-U01 Substudy 3: Efficacy and Safety Study of Pembrolizumab (MK-3475) When Used With Investigational Agents in Participants With Advanced Non-small Cell Lung Cancer (NSCLC), Previously Treated With Anti-programmed Cell Death Receptor Ligand 1 (PD-L1) Therapy (MK-3475-01C/KEYMAKER-U01C)
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Boserolimab|BIOLOGICAL: MK-4830|DRUG: diphenhydramine|DRUG: acetaminophen|BIOLOGICAL: MK-0482
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Percutaneous Stem Cell Injection Delivery Effects on Neomyogenesis Pilot Study (The POSEIDON-Pilot Study)
Status: COMPLETED
Conditions: Stem Cell Transplantation
Interventions: BIOLOGICAL: Auto-hMSCs|BIOLOGICAL: Allo-hMSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on the Preventive Effect of Intravaginal Prasterone on Recurrent Urinary Tract Infections in Postmenopausal Women
Status: WITHDRAWN
Conditions: Recurrent Urinary Tract Infection|Postmenopause|Postmenopausal Syndrome|Postmenopausal Symptoms|Menopause
Interventions: DRUG: Prasterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Postoperative Hip Bracing After Hip Arthroscopy
Status: COMPLETED
Conditions: Femoroacetabular Impingement Syndrome|Acetabular Labral Tear
Interventions: DEVICE: Hip brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: French Cohort for the Study of Non-invasive Tests of Liver Lesions in NAFLD/NASH (FreSH Cohort)
Status: RECRUITING
Conditions: NAFLD
Interventions: DIAGNOSTIC_TEST: biopsy-proven NAFLD patients with non-invasive tests of liver fibrosis (blood tests, elastography devices) and biobank
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Open Label, Randomized Study of Low Concentration Ioforminol Injections for Use in Abdominal CECT in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ioforminol 160 mgI/mL|DRUG: Ioforminol 200 mgI/mL|DRUG: Iopamidol 300 mgI/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Clinical Study to Evaluate the Efficacy and Safety of Rosuvastatin Vs CoQ10 on Nonalcoholic Steatohepatitis
Status: NOT_YET_RECRUITING
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: Rosuvastatin 20 Mg Oral Tablet|DRUG: Coenzyme Q10 100 MG Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obstructive Sleep Apnea (OSA), Oral Frailty, Dysphagia, Continuous Positive Airway Pressure (CPAP)
Status: RECRUITING
Conditions: Dysphagia|OSA|CPAP
Interventions: DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Paclitaxel (Albumin-bound) Combination With Carboplatin in Ovarian Cancer.
Status: UNKNOWN
Conditions: Ovarian Cancer
Interventions: DRUG: Paclitaxel (albumin-bound)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chewing Gum Containing Vitamin-c to Treat Emesis Gravidarum
Status: COMPLETED
Conditions: Hyperemesis Gravidarum|Nausea Gravidarum|Vitamin C Deficiency
Interventions: DIETARY_SUPPLEMENT: Pregnan-C-Gum(R) chewing gum|DIETARY_SUPPLEMENT: Placebo chewing gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Envafolimab Combined With Endostar and Concurrent Chemoradiotherapy for Locally Advanced Primary Cervical Cancer
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer
Interventions: DRUG: cis-platinum|RADIATION: radiation|DRUG: Envafolimab Injection|DRUG: Recombinant Human Endostatin Injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Research Study Looking at the Comparability of 2 Different Forms of Oral Semaglutide in Healthy People
Status: COMPLETED
Conditions: Healthy Volunteers|Type 2 Diabetes
Interventions: DRUG: Semaglutide D Dose 1|DRUG: Semaglutide D Dose 2|DRUG: Semaglutide D Dose 3|DRUG: Semaglutide Dose 4|DRUG: Semaglutide Dose 5|DRUG: Semaglutide Dose 6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation
Status: RECRUITING
Conditions: Hematologic Diseases|Acute Leukemia in Remission|Chronic Myelogenous Leukemia - Chronic Phase|Chronic Myelogenous Leukemia, Accelerated Phase|Chronic Myelogenous Leukemia, Blastic Phase|Myelodysplastic Syndromes|Mantle Cell Lymphoma|Follicular Lymphoma|Diffuse Large B Cell Lymphoma|Non Hodgkin Lymphoma|Graft Vs Host Disease|Graft-versus-host-disease
Interventions: DRUG: Vorinostat|PROCEDURE: Blood and Marrow Transplant (BMT)|DRUG: Tacrolimus (or cyclosporine)|DRUG: Methotrexate|DRUG: Mycophenolate Mofetil (MMF)|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Surgery Followed by Risk-Directed Post-Operative Adjuvant Therapy for HPV-Related Oropharynx Squamous Cell Carcinoma: "The Minimalist Trial (MINT)"
Status: ACTIVE_NOT_RECRUITING
Conditions: HPV Related Oropharyngeal Squamous Cell Carcinoma
Interventions: DRUG: Cisplatin|RADIATION: Intensity modulated radiation therapy|RADIATION: Intensity modulated proton therapy|PROCEDURE: Surgery|OTHER: FACT-H&N|OTHER: MD Anderson Dysphagia Inventory|OTHER: University of Michigan Xerostomia Index|OTHER: Scale of Subjective Total Taste Acuity|OTHER: Neck Dissection Impairment Index
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RT+ Anti-PD-1 for Patients With Advanced HCC (RT+PD-1-HCC)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Radiation therapy and systemic anti-PD-1 immunotherapy for patients with advanced hepatocellular carcinoma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Testing the Safety and Feasibility of Restorative Microbiota Therapy (RMT) in Patients With Refractory Immune-checkpoint Inhibitor-related Colitis
Status: NOT_YET_RECRUITING
Conditions: Immune-related Colitis|Colitis
Interventions: DRUG: RMT|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does Continued Use of Clopidogrel Into Surgery Cause Increased Perioperative Bleeding?
Status: COMPLETED
Conditions: Clopidogrel
Interventions: DRUG: Clopidogrel|DRUG: Discontinue Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Short Term Spironolactone for Prevention of Acute Kidney Injury After Cardiac Surgery
Status: UNKNOWN
Conditions: Acute Kidney Injuries|Kidney Injuries, Acute|Kidney Injury, Acute|Acute Renal Injury|Acute Renal Injuries
Interventions: DRUG: Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Indacaterol in Patients With Chronic Obstructive Pulmonary Disease (COPD) Using Salmeterol as Active Control
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Indacaterol 150 μg|DRUG: Salmeterol 50 μg|DRUG: Placebo to Indacaterol|DRUG: Placebo to Salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ixazomib & Rituximab After Stem Cell Transplant in Treating Patients With Mantle Cell Lymphoma in Remission
Status: ACTIVE_NOT_RECRUITING
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Ixazomib|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of FTP-198 in Healthy Australian Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: FTP-198, single dose|DRUG: Placebo, single dose|DRUG: FTP-198, multiple doses|DRUG: Placebo, multiple doses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of HEC96719 Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease|Non-alcoholic Steatohepatitis
Interventions: DRUG: HEC96719
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Efficacy of PLAtelet Aggregation Inhibition by Ticagrelor Mediated P2Y12 Blockade Dependent Upon Endogenous Endothelial Nitric OXide?
Status: COMPLETED
Conditions: Acute Coronary Syndome
Interventions: DRUG: Ticagrelor|OTHER: EndoPAT - endothelial assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web Based Tools to Improve Medication Continuity in Adolescents With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Adherence, Medication
Interventions: OTHER: Mehealth for ADHD software with medication continuity tools|OTHER: Mehealth for ADHD software with no medication continuity tools
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Diabetes Nutrition Algorithms in Patients With Overt Diabetes Mellitus
Status: UNKNOWN
Conditions: Type 2 Diabetes|NAFLD|Obesity|Dyslipoproteinaemia|Hypertension
Interventions: BEHAVIORAL: dietary consulting and advise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical PluroGel N for the Treatment of Mildly Infected Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer|Infection
Interventions: DRUG: PluroGel N|DRUG: PluroGel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Registration Trial of the Intracranial Visualized Stent for the Wide-necked Intracranial Aneurysms
Status: UNKNOWN
Conditions: Brain Diseases|Aneurysm|Intracranial Aneurysm|Cardiovascular Diseases
Interventions: DEVICE: Intracranial stent for wide-necked aneurysms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of "VS002A" With the Standard WHO-ORS in Non-cholera Acute Watery Diarrhea in Infants and Young Children
Status: COMPLETED
Conditions: Diarrhea, Infantile
Interventions: OTHER: VS002A|OTHER: WHO-ORS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of Pentamidine in Patients With Metastatic Colon Cancer Undergoing Standard Chemotherapy as Second-line and/or Third-line Treatment
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: pentamidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Atezolizumab as Adjuvant Therapy in Participants With Renal Cell Carcinoma (RCC) at High Risk of Developing Metastasis Following Nephrectomy
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Atezolizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Assessing LAS34273 in Moderate to Severe Stable Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Aclidinium bromide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Intravenous or Intraperitoneal Chemotherapy in Treating Patients With Stage II-III Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Clear Cell Adenocarcinoma|Fallopian Tube Endometrioid Adenocarcinoma|Fallopian Tube Mucinous Adenocarcinoma|Fallopian Tube Serous Adenocarcinoma|Fallopian Tube Transitional Cell Carcinoma|Fallopian Tube Undifferentiated Carcinoma|Malignant Ovarian Brenner Tumor|Ovarian Clear Cell Adenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mucinous Adenocarcinoma|Ovarian Seromucinous Carcinoma|Ovarian Serous Adenocarcinoma|Ovarian Transitional Cell Carcinoma|Ovarian Undifferentiated Carcinoma|Primary Peritoneal Clear Cell Adenocarcinoma|Primary Peritoneal Endometrioid Adenocarcinoma|Primary Peritoneal Serous Adenocarcinoma|Primary Peritoneal Transitional Cell Carcinoma|Primary Peritoneal Undifferentiated Carcinoma|Stage II Fallopian Tube Cancer AJCC v6 and v7|Stage II Ovarian Cancer AJCC v6 and v7|Stage IIA Fallopian Tube Cancer AJCC v6 and v7|Stage IIA Ovarian Cancer AJCC V6 and v7|Stage IIB Fallopian Tube Cancer AJCC v6 and v7|Stage IIB Ovarian Cancer AJCC v6 and v7|Stage IIC Fallopian Tube Cancer AJCC v6 and v7|Stage IIC Ovarian Cancer AJCC v6 and v7|Stage III Ovarian Cancer AJCC v6 and v7|Stage III Primary Peritoneal Cancer AJCC v7|Stage IIIA Ovarian Cancer AJCC v6 and v7|Stage IIIA Primary Peritoneal Cancer AJCC v7|Stage IIIB Ovarian Cancer AJCC v6 and v7|Stage IIIB Primary Peritoneal Cancer AJCC v7|Stage IIIC Ovarian Cancer AJCC v6 and v7|Stage IIIC Primary Peritoneal Cancer AJCC v7|Stage IV Fallopian Tube Cancer AJCC v6 and v7|Stage IV Ovarian Cancer AJCC v6 and v7|Stage IV Primary Peritoneal Cancer AJCC v7
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Carboplatin|DRUG: Carboplatin|DRUG: Cisplatin|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|DRUG: Paclitaxel|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Constraint-induced Movement Therapy With Home-based Hand-arm Bimanual Intensive Therapy in Children With Unilateral Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy, Spastic Hemiplegic
Interventions: OTHER: CIMT|OTHER: H-HABIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Lidocaine in Children Undergoing Laparoscopic Appendectomy
Status: COMPLETED
Conditions: Acute Appendicitis|Postoperative Pain|Postoperative Nausea and Vomiting
Interventions: DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of the Neurent Medical NEUROMARK™ System in Subjects With Chronic Rhinitis
Status: COMPLETED
Conditions: Chronic Rhinitis
Interventions: DEVICE: NEUROMARK™ System|DEVICE: Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Monocanalicular Versus Bicanalicular Intubation in the Treatment of Congenital Nasolacrimal Duct Obstruction
Status: COMPLETED
Conditions: Nasolacrimal Duct Obstruction
Interventions: DEVICE: Canalicular intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Open-label, Three-arm Study of MZRW on Tolerability, Exposure and Pharmacokinetics
Status: COMPLETED
Conditions: Functional Constipation|Gastrointestinal Disorders
Interventions: DRUG: MZRW
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prove of Concept Study, to Evaluate the Efficacy, Safety, and Tolerability of IBEROGAST in the Treatment of Bowel Troubles in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Gastrointestinal Disorders in Parkinson's Disease
Interventions: DRUG: IBEROGAST
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Alternative Medical Therapies in Primary Hyperparathyroidism
Status: COMPLETED
Conditions: Primary Hyperparathyroidism
Interventions: DRUG: eplerenone|DRUG: amiloride|DRUG: Placebo|DRUG: Cinacalcet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Approach to Cardiovascular Health by Optimizing Risk Management (ANCHOR)
Status: COMPLETED
Conditions: Cardiovascular Risk Reduction of Having a Coronary Event
Interventions: BEHAVIORAL: Minimal Intervention|BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Motivational Enhancement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of the Tumor Saturation and Biological Activity of MEDI-522 (Abergrin) in Patients With Advanced Malignant Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: BIOLOGICAL: MEDI-522
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Dara-CyBorD in Newly Diagnosed Multiple Myeloma Patients With Renal Failure
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma|Renal Failure
Interventions: COMBINATION_PRODUCT: Daratumumab-hyaluronidase in Combination with Bortezomib, Cyclophosphamide, and Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive D-Cycloserine in Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: D-cycloserine|DEVICE: Transcranial Magnetic Stimulator|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Pilot Safety Study of MDMA-assisted Therapy for Social Anxiety in Autistic Adults
Status: COMPLETED
Conditions: Social Anxiety in Autistic Adults
Interventions: DRUG: Placebo|DRUG: Midomafetamine|BEHAVIORAL: Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post Marketing Study of MagnetOs Putty Compared to Local Autograft in Patients Undergoing Posterolateral Lumbar Fusion
Status: COMPLETED
Conditions: Degenerative Disc Disease|Spine Fusion
Interventions: DEVICE: MagnetOs Putty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Adding Interferential Current to Pelvic Floor Muscle Training on Vaginismus
Status: NOT_YET_RECRUITING
Conditions: Vaginismus
Interventions: OTHER: Pelvic floor training|DEVICE: Interferential current|BEHAVIORAL: General advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IOL-capsular Complex After Different Intraocular Lenses Implantation in Patients With High Myopia
Status: UNKNOWN
Conditions: Age-related Cataract
Interventions: PROCEDURE: one-piece|PROCEDURE: plate-haptic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Of Different Orthodontic Aligner Systems Applied On Single Stage And Three Stage
Status: COMPLETED
Conditions: Tooth Crowding|Tooth; Lesion, White Spot Lesions
Interventions: DEVICE: EonAligner|DEVICE: Clearfix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ONO-4538 in Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: ONO-4538|DRUG: Oxaliplatin|DRUG: Tegafur- Gimeracil-Oteracil potassium|DRUG: Capecitabine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antilipidemic Ezetimibe Induces Regression of Endometriotic Explants in a Rat Model of Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: PROCEDURE: Surgical induction of endometriotic explants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Pharmacokinetics of Pelacarsen (TQJ230) in Participants With Mild Hepatic Impairment Compared to Matched Healthy Participants
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Pelacarsen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Lazertinib in Participants With Epidermal Growth Factor Receptor (EGFR) Mutation Positive Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Lazertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiotherapy With Hyperthermia in Unresectable or Marginally Resectable Soft Tissue Sarcomas
Status: UNKNOWN
Conditions: Sarcoma|Alveolar Soft Part Sarcoma|Clear Cell Sarcoma|Malignant Peripheral Nerve Sheath Tumors|Myxoid Liposarcoma|Liposarcoma, Dedifferentiated|Synovial Sarcoma|Leiomyosarcoma|Undifferentiated Pleomorphic Sarcoma|Fibrosarcoma|Pleomorphic Rhabdomyosarcoma
Interventions: RADIATION: Hypofractionated radiotherapy|OTHER: Hyperthermia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Talazoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Infarction Exercise Effects on Myocardial Function Assessed by 2D Strain Ultrasound
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: OTHER: Cardiac training program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Administration of Epstein Barr Virus - Specific Cytotoxic T-Lymphocytes to Metastatic EBV-Positive Nasopharygneal Cancer
Status: COMPLETED
Conditions: Nasopharyngeal Cancer
Interventions: BIOLOGICAL: EBV-Specific CTLs and CD45 Mab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Oxidation Rates of the Different Substrates During Exercise in Children and Adolescents With Juvenile Idiopathic Arthritis. Case-control Study and Cases Treated / Cases Not Treated With Anti-TNFα
Status: UNKNOWN
Conditions: Juvenile Idiopathic Arthritis
Interventions: OTHER: anti-TNFα
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Suppression Of Atrial Fibrillation With Ranolazine After Cardiac Surgery
Status: TERMINATED
Conditions: Heart; Dysfunction Postoperative, Cardiac Surgery
Interventions: DRUG: Ranolazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Women Abuse and the Role of the Family Doctor.
Status: TERMINATED
Conditions: Improved Recognition of Partner Abuse|Gender Differences in Discussing Partner Abuse|Abused Women's Expectations,Experiences|Abused Women's Health Care Utilisation
Interventions: BEHAVIORAL: a training to improve recognition of partner abuse.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: ECT
Clinical trial: Management of Supraventricular Tachycardia of Children
Status: UNKNOWN
Conditions: Supraventricular Tachycardia
Interventions: DRUG: adenosine,Propranolol,flecainide, amiodarone, propranolol, digoxin and procainamide.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Standard Radiation Therapy With or Without Stereotactic Radiation Therapy in Treating Patients With Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: RADIATION: radiation therapy|RADIATION: stereotactic radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: POST: Comparison of Macintosh Laryngoscope vs Video Laryngoscope in Patients Intubated by Anaesthesia Trainee
Status: COMPLETED
Conditions: Sore Throat
Interventions: DEVICE: Video Laryngocope|DEVICE: Macintosh Conventional Laryngocope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Using Ferumoxytol-Enhanced MRI to Measure Inflammation in Patients With Brain Tumors or Other Conditions of the CNS
Status: COMPLETED
Conditions: Brain Injury|Central Nervous System Degenerative Disorder|Central Nervous System Infectious Disorder|Central Nervous System Vascular Malformation|Hemorrhagic Cerebrovascular Accident|Ischemic Cerebrovascular Accident|Primary Brain Neoplasm|Brain Cancer|Brain Tumors
Interventions: DRUG: Ferumoxytol|OTHER: Tissue Analysis|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC