pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cord Clamping Level Above or Below Mother's Perineum
Status: COMPLETED
Conditions: Pre-term Birth|Delayed Cord Clamping
Interventions: PROCEDURE: Delayed cord clamping above the perineum|PROCEDURE: Delayed cord clamping below the perineum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Abiraterone Acetate, Niclosamide, and Prednisone in Treating Patients With Hormone-Resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Prostate Carcinoma|Recurrent Prostate Carcinoma|Stage IV Prostate Cancer
Interventions: DRUG: Abiraterone Acetate|DRUG: Niclosamide|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Trial of Zonisamide for Myoclonus Dystonia
Status: COMPLETED
Conditions: Myoclonus Dystonia
Interventions: DRUG: zonegran|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Chinese Herbal Medicine Concurrent With Secukinumab for Severe Plaque Psoriasis
Status: UNKNOWN
Conditions: Psoriasis
Interventions: DRUG: Gu Ben Hua Yu Fang decoction (Chinese herbal medicine)|DRUG: Secukinumab Auto-Injector [Cosentyx]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Hyoscine Butylbromide Tablets for the Treatment of Occasional or Recurrent Episodes of Gastric or Intestinal Spasm-like Pain or Discomfort
Status: COMPLETED
Conditions: Abdominal Pain
Interventions: DRUG: Hyoscine Butylbromide - Tablet|DRUG: Hyoscine Butylbromide - Capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HAL-RAR Versus Hemorrhoidectomy in the Treatment of Grade III-IV Hemorrhoids. Prospective, Randomized Trial
Status: COMPLETED
Conditions: Hemorrhoids|Pain, Postoperative
Interventions: PROCEDURE: Hemorrhoidectomy|PROCEDURE: HAL-RAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Eluting Balloon in peripherAl inTErvention For Below The Knee Angioplasty Evaluation
Status: COMPLETED
Conditions: Critical Limb Ischemia
Interventions: DEVICE: PEB|DEVICE: POBA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-MI PET Scan Imaging of Inflammation
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reactive vs. Proactive Pain Control in IBD
Status: TERMINATED
Conditions: Inflammatory Bowel Diseases|Pain|Opioid Use|Crohn Disease|Ulcerative Colitis
Interventions: BEHAVIORAL: Proactive Analgesic Inpatient Narcotic-Sparing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Clinical Trial of the Safety and Anti-Tumor Activity of AB-201 in Subjects With Advanced HER2+ Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Gastric Cancer|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: AB-201|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chest Compression and Sustained Inflation
Status: COMPLETED
Conditions: Newborn Infants Having Asystole or Bradycardia at Birth
Interventions: PROCEDURE: CC+SI|PROCEDURE: 3:1 CPR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repeat-Dose Pharmacokinetics and Pharmacodynamics of Bortezomib in Patients With Relapsed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monopolar and Bipolar in Esophageal ESD
Status: WITHDRAWN
Conditions: Esophageal Neoplasm|Esophageal Polyp|Endoscopic Submucosal Dissection|Bipolar Electocautery
Interventions: PROCEDURE: Endoscopic Submucosal Dissection|DEVICE: Bipolar electrocautery knife
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Immunogenicity of Quadrivalent LAIV (MEDI8662) in Adults 18 to 49 Years of Age
Status: COMPLETED
Conditions: Healthy or Stable Underlying Chronic Medical Condition
Interventions: BIOLOGICAL: Q/LAIV-BFS (MEDI8662)|BIOLOGICAL: FluMist/B/Yamagata|BIOLOGICAL: FluMist/B/Victoria
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Levosimendan Versus Dobutamine for Renal Function in Heart Failure
Status: COMPLETED
Conditions: Cardiorenal Syndrome
Interventions: DRUG: Levosimendan|DRUG: Dobutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dynamic Splinting for Plantarflexion in Spastic Hemiplegia
Status: WITHDRAWN
Conditions: Spastic Hemiplegia
Interventions: DEVICE: Ankle Dorsiflexion Dynasplint|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HighCycle: Effect of Acetazolamide on Pulmonary Artery Pressure in Women Compared to Men
Status: RECRUITING
Conditions: High Altitude
Interventions: DRUG: Acetazolamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High Intensity LED Photobiomodulation Therapy for Chronic Leg and Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: High intensity LED light device|DEVICE: Sham LED light device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gait Pattern Between a Cemented and Non-cemented Femur Stem
Status: COMPLETED
Conditions: Gait Analysis|Hip Fractures|Hip Arthroplasty|Randomized
Interventions: OTHER: Gait analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ENDEAVOUR: Phase 3 Multicenter Study of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)
Status: COMPLETED
Conditions: Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)|Amyloidosis, Hereditary|Amyloid Neuropathies, Familial|Amyloid Neuropathies|Amyloidosis, Hereditary, Transthyretin-Related|Familial Transthyretin Cardiac Amyloidosis
Interventions: DRUG: Revusiran (ALN-TTRSC)|DRUG: Sterile Normal Saline (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Theraworx Bath Wipes Versus Standard Bath Wipes in the Reduction of Vancomycin-Resistant Enterococci
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplantation|Vancomycin-Resistant Enterococci
Interventions: OTHER: Theraworx™ bath wipes|OTHER: Standard bath wipes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of LAF237 on Glucagon Secretion in Patients With Type 2 Diabetes and in Healthy Subjects
Status: COMPLETED
Conditions: Type-2 Diabetes|Healthy
Interventions: DRUG: Vildagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TCP Regimen in Newly Diagnosed MCD:a Prospective, Single-center, Single-arm, Phase-II Pilot Trial
Status: UNKNOWN
Conditions: Multicentric Castleman Disease
Interventions: DRUG: Thalidomide, cyclophosphamide and prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strongest Families (Formerly Family Help Program): Pediatric Attention Deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit/Hyperactivity Disorder
Interventions: BEHAVIORAL: FHPADHD|BEHAVIORAL: ADHD Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Additive Effect of Ezetimibe Upon Simvastatin During Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Simvastatin|DRUG: Ezetimibe-Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: 30-Minute Light Exposure for the Treatment of Seasonal Affective Disorder
Status: COMPLETED
Conditions: Seasonal Affective Disorder
Interventions: DEVICE: goLITE|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Chidamide as a Single-agent Treatment for Patients With Relapse or Refractory B-NHL
Status: UNKNOWN
Conditions: Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma (NHL)
Interventions: DRUG: Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Isoenergetic High Intensity Interval Training and Moderate Intensity Training in Adults With Type I Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: OTHER: High Intensity Interval Exercise|OTHER: Moderate Intensity Continuous Exercise|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ologen® Collagen Matrix Versus Mitomycin-C in Patients With Juvenile-onset Open Angle Glaucoma
Status: COMPLETED
Conditions: Open Angle Glaucoma
Interventions: PROCEDURE: ologen® Collagen Matrix|PROCEDURE: Trabeculectomy with low dose mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of CG100649 Versus Celecoxib in Osteoarthritis Patients
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: CG100649|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ixabepilone and Cyclophosphamide as Neoadjuvant Therapy in HER-2 Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Ixabepilone|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of MGD007 in Relapsed/Refractory Metastatic Colorectal Carcinoma
Status: COMPLETED
Conditions: Colorectal Carcinoma
Interventions: DRUG: MGD007
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Doses of AMG 139 in Healthy and Crohn's Disease Subjects
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: AMG 139
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Effect of Nesinaact on Non-alcoholic Steatohepatitis Through MRI and Liver Fibroscan in Patients With Type 2 Diabetes
Status: UNKNOWN
Conditions: Non-alcoholic Steatohepatitis|Type2 Diabetes
Interventions: DRUG: Nesinaact 25/15 (Alogliptin benzoate 25mg, pioglitazone hydrochloride 15mg) treatment for 24 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurological Dry Eye Study Stimulating Both Lacrimal and Vagus Nerves
Status: NOT_YET_RECRUITING
Conditions: Dry Eye Disease|Dry Eye
Interventions: DIETARY_SUPPLEMENT: NeuroTears|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: TGRX-326 Phase I/II Pharmacokinetic Study
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: cycle 1: treatment drug|DRUG: cycle 1: reference drug|BEHAVIORAL: cycle 1: fasted|BEHAVIORAL: cycle 1: food|DRUG: cycle 2: treatment drug|DRUG: cycle 2: reference drug|BEHAVIORAL: cycle 2: fasted|BEHAVIORAL: cycle 2: food|DRUG: cycle 3: treatment drug|DRUG: cycle 3: reference drug|BEHAVIORAL: cycle 3: fasted|BEHAVIORAL: cycle 3: food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Selected Evidence-based Practices and Related Nurses' Education on the Incidence and Severity of Ventilator-associated Pneumonia
Status: COMPLETED
Conditions: Evidence-based Practices|Nursing Education|Incidence|Ventilator-associated Pneumonia
Interventions: OTHER: Ventilator-associated pneumonia prevention Evidence-based practices (VAPPEBP) which consists of ten items bundle
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Exploratory Study of MT-2990 in Patients With AAV
Status: RECRUITING
Conditions: Antineutrophil Cytoplasmic Antibody (ANCA) -Associated Vasculitis (AAV)
Interventions: DRUG: MT-2990
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Oxytocin on Romantic Jealousy
Status: COMPLETED
Conditions: Sexual Infidelity|Emotional Infidelity|Jealousy
Interventions: BEHAVIORAL: Sexual Infidelity Condition|BEHAVIORAL: Emotional Infidelity Condition|BEHAVIORAL: Neutral Condition|BEHAVIORAL: Player in Jealousy Condition|BEHAVIORAL: Player in Non-Jealousy Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of the TransPyloric Shuttle™ (TPS™) for Weight Reduction in Obese Subjects
Status: COMPLETED
Conditions: Obesity
Interventions: DEVICE: BAROnova™ TransPyloric Shuttle™ (TPS™)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Effectiveness of Distributing Micronutrient Sprinkles to Reduce Prevalence of Anemia
Status: COMPLETED
Conditions: Anemia
Interventions: DIETARY_SUPPLEMENT: "Sprinkles" containing mulitple micronutrients|BEHAVIORAL: Education/communication on use of micronutrient sprinkles|DIETARY_SUPPLEMENT: Fortified food aid (corn-soy blend)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Non-Small Cell Carcinoma|Stage I Colorectal Cancer AJCC v8|Stage I Lung Cancer AJCC v8|Stage IA1 Lung Cancer AJCC v8|Stage IA2 Lung Cancer AJCC v8|Stage IA3 Lung Cancer AJCC v8|Stage IB Lung Cancer AJCC v8|Stage II Colorectal Cancer AJCC v8|Stage II Lung Cancer AJCC v8|Stage IIA Colorectal Cancer AJCC v8|Stage IIA Lung Cancer AJCC v8|Stage IIB Colorectal Cancer AJCC v8|Stage IIB Lung Cancer AJCC v8|Stage IIC Colorectal Cancer AJCC v8|Stage III Colorectal Cancer AJCC v8|Stage III Lung Cancer AJCC v8|Stage IIIA Colorectal Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Colorectal Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Colorectal Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Survivorship Care Plan|OTHER: Telemedicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sunitinib Before and After Surgery in Treating Patients With Metastatic Kidney Cancer That Can Be Removed By Surgery
Status: TERMINATED
Conditions: Kidney Cancer
Interventions: DRUG: sunitinib malate|GENETIC: gene expression analysis|GENETIC: reverse transcriptase-polymerase chain reaction|GENETIC: western blotting|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|PROCEDURE: adjuvant therapy|PROCEDURE: neoadjuvant therapy|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: KSD-101 Therapy for EBV-associated Lymphomas: an Exploratory Clinical Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: EBV-associated Lymphomas
Interventions: BIOLOGICAL: Autologous monocyte-derived DCs pulsed withEBV-associated antigen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tanespimycin and Bortezomib in Treating Patients With Advanced Solid Tumors or Lymphomas
Status: TERMINATED
Conditions: Adult Grade III Lymphomatoid Granulomatosis|AIDS-related Peripheral/Systemic Lymphoma|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Nodal Marginal Zone B-cell Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Stage III Adult Burkitt Lymphoma|Stage III Adult Diffuse Large Cell Lymphoma|Stage III Adult Diffuse Mixed Cell Lymphoma|Stage III Adult Diffuse Small Cleaved Cell Lymphoma|Stage III Adult Hodgkin Lymphoma|Stage III Adult Immunoblastic Large Cell Lymphoma|Stage III Adult Lymphoblastic Lymphoma|Stage III Adult T-cell Leukemia/Lymphoma|Stage III Cutaneous T-cell Non-Hodgkin Lymphoma|Stage III Grade 1 Follicular Lymphoma|Stage III Grade 2 Follicular Lymphoma|Stage III Grade 3 Follicular Lymphoma|Stage III Mantle Cell Lymphoma|Stage III Marginal Zone Lymphoma|Stage III Mycosis Fungoides/Sezary Syndrome|Stage III Small Lymphocytic Lymphoma|Stage IV Adult Burkitt Lymphoma|Stage IV Adult Diffuse Large Cell Lymphoma|Stage IV Adult Diffuse Mixed Cell Lymphoma|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma|Stage IV Adult Hodgkin Lymphoma|Stage IV Adult Immunoblastic Large Cell Lymphoma|Stage IV Adult Lymphoblastic Lymphoma|Stage IV Adult T-cell Leukemia/Lymphoma|Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma|Stage IV Grade 1 Follicular Lymphoma|Stage IV Grade 2 Follicular Lymphoma|Stage IV Grade 3 Follicular Lymphoma|Stage IV Mantle Cell Lymphoma|Stage IV Marginal Zone Lymphoma|Stage IV Mycosis Fungoides/Sezary Syndrome|Stage IV Small Lymphocytic Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific|Waldenström Macroglobulinemia
Interventions: DRUG: tanespimycin|DRUG: bortezomib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prehabilitation, Rehabilitation and Comprehensive Approach to the Sequelae of Brain Tumors
Status: RECRUITING
Conditions: Brain Tumor
Interventions: PROCEDURE: Non-invasive neuromodulation (TMS and/or tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Systematic Therapy and Bronchoscopic Interventional Treatment for Pulmonary Mucormycosis
Status: ENROLLING_BY_INVITATION
Conditions: Pulmonary Mucormycosis
Interventions: PROCEDURE: transbronchoscopic interventional debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TMC278-TiDP6-C130: Pharmacokinetics, Safety and Tolerability of TMC278 in Subjects With Mildly or Moderately Impaired Hepatic Function.
Status: COMPLETED
Conditions: HIV|AIDS|Hepatic Impairment
Interventions: DRUG: TMC278
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Investigation of Efficacy and Tolerability of WO 2707, a MoistCream Cremolum, in Postmenopausal Women Suffering From Symptoms of Vaginal Dryness
Status: COMPLETED
Conditions: Vaginal Atrophy
Interventions: DEVICE: WO 2707
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 10 600 nm Ablative Fractional Laser Treatment of Scars: a Prospective Single Blinded Within Patient Controlled Randomized Trial
Status: COMPLETED
Conditions: Scars After Surgical Intervention
Interventions: PROCEDURE: Laser treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Ranging Study of Intranasal Kovacaine Mist in Pediatric Subjects
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: 400uL of Kovacaine Mist|DRUG: 200uL of Kovacaine Mist|DRUG: 120uL of Kovacaine Mist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 12-Month Efficacy and Safety of Diepalrestat in Adults With Diabetic Peripheral Neuropathy, a DB, Placebo-Controlled Study
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy
Interventions: DRUG: diepalrestat choline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of ALXN1840 Administered for 48 Weeks Versus Standard of Care in Participants With Wilson Disease
Status: TERMINATED
Conditions: Wilson Disease
Interventions: DRUG: ALXN1840|DRUG: SoC Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIV and STD Prevention for High-Risk, Inner-City, African American Youth
Status: COMPLETED
Conditions: HIV Infections|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: Social Skills Training|BEHAVIORAL: Mass media|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study to Compare Ibuprofen + Caffeine With Ibuprofen Alone in the Treatment of Headache
Status: UNKNOWN
Conditions: Headache
Interventions: DRUG: Ibuprofen plus caffeine|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: "Comparison of the Efficacy and Safety of Adalimumab to That of Tocilizumab in Severe Uveitis of Behçet's Disease"
Status: NOT_YET_RECRUITING
Conditions: Behcet's Uveitis
Interventions: DRUG: Adalimumab|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Outcomes Study to Measure Reduction in Pain and Numbness During Administration of an Amino Acid Formulation in Subjects Diagnosed With Peripheral Neuropathy
Status: UNKNOWN
Conditions: Diabetic Neuropathy|Chemotherapy Induced Neuropathy|HIV Neuropathy|Trauma Induced Neuropathy
Interventions: DRUG: Neuron012703 (Medical Food)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Contact Lens Coefficient of Friction (CoF) on the Development of Lid Wiper Epitheliopathy (LWE)
Status: COMPLETED
Conditions: Lid Wiper Epitheliopathy
Interventions: DEVICE: Acuvue Oasys|DEVICE: Air Optix Night & Day Aqua
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial of BEKINDA (Ondansetron 12 mg Bimodal Release Tablets) for Diarrhea Predominant Irritable Bowel Syndrome (IBS-D)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Diarrhea
Interventions: DRUG: BEKINDA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Online Real-time CPR Training
Status: UNKNOWN
Conditions: Cardiopulmonary Resuscitation|Education
Interventions: OTHER: Online real-time quality measurement and feedback video-based CPR training|OTHER: Online real-time feedback video-based CPR training without quality measurement|OTHER: Conventional CPR training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Non-invasive Neuromodulation Guided Through Biomarkers in Patients With Stroke Sequels
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: rTMSc|BEHAVIORAL: Neurofunctional physiotherapy|DEVICE: rTMS sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Refractive Accuracy of "2WIN" and Portable Autorefractors
Status: COMPLETED
Conditions: Refractive Error - Myopia Axial|Astigmatism|Accomodation|Visual Impairment|Hyperopia of Both Eyes
Interventions: DEVICE: "2WIN" Photoscreener|DEVICE: "Plusoptix A12"|DEVICE: "Retinomax"
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ticagrelor vs Clopidogrel for Platelet Inhibition in Stenting for Cerebral Aneurysm
Status: COMPLETED
Conditions: Cerebral Aneurysm
Interventions: DRUG: Clopidogrel|DRUG: Ticagrelor|DRUG: aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefits of an Aerobic and Strength Rehabilitation Program With Post- SARS-CoV-2 Patients Moderate-severe
Status: NOT_YET_RECRUITING
Conditions: COVID-19
Interventions: OTHER: Aerobic plus strength group|OTHER: Aerobic group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SASS 2 : Self Assembled Skin Substitute for the Autologous Treatment of Severe Burn Wounds in Acute Stage of Burn Trauma
Status: RECRUITING
Conditions: Burns
Interventions: BIOLOGICAL: Self assembled skin substitute (SASS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GALLEX 4 - Long-Term Extension Study to Evaluate Tesaglitazar Therapy in Patients With Type 2 Diabetes
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DRUG: Tesaglitazar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Drug Absorption of Fixed Dose Combinations of Budesonide, Glycopyrronium, and Formoterol
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Treatment A|DRUG: Treatment B|DRUG: Treatment C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Glutamine Therapy for Hemolysis-Associated Pulmonary Hypertension
Status: COMPLETED
Conditions: Pulmonary Hypertension|Sickle Cell Disease|Thalassemia
Interventions: DRUG: L-Glutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enzalutamide in First Line Androgen Deprivation Therapy for Metastatic Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms
Interventions: DRUG: Enzalutamide|DRUG: NSAA|DRUG: LHRHA or Surgical Castration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sevoflurane PharmacokInetics in ARDS
Status: TERMINATED
Conditions: Acute Respiratory Distress Syndrome
Interventions: DRUG: Deep sedation by Sevoflurane on the Morphotype of ARDS in ICU patieNts
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predicting the Response of Patients With Rheumatoid Arthritis to Treatment With Genetically Engineered Biological Drugs and Janus (JAK) Kinase Inhibitors
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: genetically engineered biological drugs, Janus-kinase inhibitors, tumor necrosis factor inhibitors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Optic Nerve Sheath Diameter in Children Receiving Caudal Block According to Anesthetic Agents: Total Intravenous Anesthesia vs. Volatile Anesthesia
Status: COMPLETED
Conditions: Caudal Block for Postoperative Analgesia
Interventions: DRUG: Propofol|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Body-Oriented Therapy for Sexual Abuse Recovery
Status: COMPLETED
Conditions: Child Abuse, Sexual|Post-Traumatic Stress Disorder|Dissociation
Interventions: BEHAVIORAL: Body-Oriented Therapy|BEHAVIORAL: Standardized Massage Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SCH 58235 (Ezetimibe) When Added to Ongoing Therapy With a Statin in Participants With Primary Hypercholesterolemia, Known Coronary Heart Disease, or Multiple Cardiovascular Risk Factors (P02173)
Status: COMPLETED
Conditions: Primary Hypercholesterolemia
Interventions: DRUG: Ezetimibe|DRUG: Placebo|DRUG: Simivastatin|DRUG: Statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Metastatic or Locally Advanced Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer|Transitional Cell Cancer of the Renal Pelvis and Ureter
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: doxorubicin hydrochloride|DRUG: gemcitabine hydrochloride|DRUG: ifosfamide|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Modified FOLFIRINOX Alternated With Biweekly Gemcitabine Plus Nab-Paclitaxel Untreated Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Folfirinox alternating with Gemcitabine-nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rivastigmine in Multiple Sclerosis Patients With Cognitive Impairment
Status: TERMINATED
Conditions: Multiple Sclerosis|Cognitive Impairment
Interventions: DRUG: Rivastigmine transdermal patch|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HSV-tk and XRT and Chemotherapy for Newly Diagnosed GBM
Status: RECRUITING
Conditions: Glioblastoma|Anaplastic Astrocytoma
Interventions: DRUG: ADV/HSV-tk (gene therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab With or Without Sunitinib in Sunitinib-Refractory Renal Cell Carcinoma
Status: WITHDRAWN
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Sunitinib|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Muscle Energy Technique and Postural Correction Exercises in Lordotic Females Wearing High Heels
Status: COMPLETED
Conditions: Lordosis|Low Back Pain
Interventions: OTHER: Muscle Energy Technique|OTHER: Postural Correction Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Modulation of the Intestinal Creatine Kinase System in Inflammatory Bowel Disease (IBD)
Status: WITHDRAWN
Conditions: Colitis, Ulcerative
Interventions: DRUG: Creatine monohydrate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Armour® Thyroid Compared to Synthetic T4 (Levothyroxine) in Previously Hypothyroid Participants
Status: COMPLETED
Conditions: Hypothyroidism|Thyroid Disease|Euthyroid|Thyroid Gland|Thyroid Hormones
Interventions: DRUG: Armour® Thyroid|DRUG: Levothyroxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Function and Pain Following Knee Replacement
Status: COMPLETED
Conditions: Knee Arthropathy|Post Operative Pain|Pain, Postoperative
Interventions: PROCEDURE: Femoral nerve block|PROCEDURE: Intra-articular block
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implant Stability in Autogenous Mineralized and Demineralized Dentin Grafts
Status: ACTIVE_NOT_RECRUITING
Conditions: Edentulous Alveolar Ridge
Interventions: DEVICE: Dental Implant Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Creatine Supplementation on Muscle Function in Childhood Myositis
Status: COMPLETED
Conditions: Juvenile Dermatomyositis
Interventions: DIETARY_SUPPLEMENT: Creapure|DIETARY_SUPPLEMENT: Glucose Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Atezolizumab and Bevacizumab Pre-Liver Transplantation for Patients With Hepatocellular Carcinoma Beyond Milan Criteria
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Hepatocellular Cancer
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Immunoglobulin (IVIG) for Treatment of Unexplained Secondary Recurrent Miscarriage
Status: COMPLETED
Conditions: Miscarriage, Recurrent|Abortion, Habitual
Interventions: BIOLOGICAL: Gamimune N or Gamunex 10%|OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing and Standardizing 129Xe Gas Exchange MRI to Visualize Regional Therapy Response in Interstitial Lung Disease
Status: RECRUITING
Conditions: Interstitial Lung Diseases
Interventions: DRUG: Hyperpolarized 129Xe
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Exercise Intolerance in Non-obstructive Hypertrophic Cardiomyopathy
Status: RECRUITING
Conditions: Hypertrophic Cardiomyopathy
Interventions: BEHAVIORAL: Moderate Intensity Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Patients Admitted to a Cardiac Intensive Care Unit With Acute CardioVascular Disease
Status: RECRUITING
Conditions: Cardiogenic Shock|Acute Decompensated Heart Failure|Acute Pulmonary Embolism|Acute Myocardial Infarction
Interventions: OTHER: Admission in the Cardiac Intensive Care Unit (CICU)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Candesartan Cilexetil + Chlorthalidone + Amlodipine Versus Exforge HCT®️ for Systemic Arterial Hypertension
Status: RECRUITING
Conditions: Hypertension
Interventions: DRUG: candesartan cilexetil + chlorthalidone + amlodipine|DRUG: Exforge HCT® (valsartan 160mg + hydrochlorothiazide 12.5mg + amlodipine 5mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Automated Care Pathway for Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: TERMINATED
Conditions: Pulmonary Disease, Chronic Obstructive|Pulmonary Diseases, Obstructive
Interventions: OTHER: Automatic inclusion of COPD orders in admission orders|OTHER: Dynamic, end-user order set design
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A New Objective Titration Procedure for the Treatment of Mandibular Advancement Device in OSAHS Patients
Status: RECRUITING
Conditions: Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)
Interventions: PROCEDURE: titration procedure for MAD treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sciatic Nerve Block Using the Subgluteal Space Approach: A Comparison With the Infragluteal Approach
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: PROCEDURE: Infragluteal space group|PROCEDURE: Subgluteal space group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Eswt on Muscle Architecture
Status: UNKNOWN
Conditions: Tendinopathy
Interventions: OTHER: Extracorporeal shockwave theraphy for hamstring tendinopathy|OTHER: Extracorporeal shockwave theraphy for quadriceps tendinopathy|OTHER: Extracorporeal shockwave theraphy for achilles tendinopathy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Proton-pump Inhibitor Tests for Chinese Reflux Patients in Relation to the CYP2C19 Genotypes
Status: COMPLETED
Conditions: GERD
Interventions: DRUG: rabeprazole|DRUG: pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Melatonin's Effect on Pain and Blood Loss After Cesarean Section
Status: COMPLETED
Conditions: Post Partum Haemorrhage in Patients Undergoing Cesarean Section
Interventions: DRUG: melatonin 3mg|DRUG: melatonin 6mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy With or Without Radiation Therapy in Treating Children With Brain Tumors
Status: UNKNOWN
Conditions: Brain and Central Nervous System Tumors|Neuroblastoma
Interventions: DRUG: carboplatin|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: methotrexate|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of One Versus Two Amino Acid Chelated Iron Capsules on Prevention of Iron Deficiency Anemia in Non-anemic Women With Twin Gestations
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: 27 mg elemental iron|DRUG: 54 mg elemental iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Magnesium Sulphate and Rocuronium in Patients Over 60
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Magnesium Sulfate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nonmyeloablative Preparative Regimen Using Mylotarg for Patients With High Risk Acute Myeloid Leukemia (AML), Acute Lymphocytic Leukemia (ALL), Chronic Myeloid Leukemia (CML) and Myelodysplastic Syndrome (MDS)
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: Mylotarg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthy Combine Study
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nicotinamide|DRUG: Lanthanum Carbonate|DRUG: Lanthanum Carbonate Placebo|DRUG: Nicotinamide Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Internet-delivered CBM-C for OC-symptoms
Status: COMPLETED
Conditions: Obsessive-compulsive Disorders and Symptoms|Obsessive Thoughts|Obsessive Compulsive Behavior
Interventions: BEHAVIORAL: Internet-delivered Combined Cognitive Bias Modification (iCBM-C)|BEHAVIORAL: Internet-delivered Cognitive Bias Modification-Interpretation (iCBM-I)|BEHAVIORAL: Internet-delivered Cognitive Bias Modification-Attention (iCBM-A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Simplified Patient-Centered Educational Tool for Improved Hearing-Aid Outcomes
Status: COMPLETED
Conditions: Hearing Loss
Interventions: OTHER: Hearing-Aid Informational Guide|OTHER: Hearing-Aid DVD|BEHAVIORAL: Teach-back Technique|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas
Status: ACTIVE_NOT_RECRUITING
Conditions: Neurofibromatosis 1 (NF1)|Plexiform Neurofibromas (PN)
Interventions: DRUG: Selumetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma Patients
Status: RECRUITING
Conditions: Glioblastoma|Glioma|Glioblastoma Multiforme|Glioma, Malignant
Interventions: DRUG: AZD1390
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of Drug to Treat Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Lurasidone 20 mg|DRUG: Lurasidone 40 mg|DRUG: Lurasidone 80mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of AMN107 With Imatinib in Gastrointestinal Stromal Tumors (GIST)
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: AMN107, STI571
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: H101 Combined With Camrelizumab for Recurrent Cervical Cancer
Status: NOT_YET_RECRUITING
Conditions: Uterine Cervical Neoplasms|Oncolytic Virotherapy|Camrelizumab
Interventions: DRUG: Recombinant human adenovirus type 5＋Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Patient Comfort With Two Different Multi-Purpose Disinfecting Solutions
Status: UNKNOWN
Conditions: Contact Lens Solution Toxicity
Interventions: OTHER: RevitaLens|OTHER: OptiFree PureMoist
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Radiation Therapy and Bortezomib and Cetuximab With or Without Cisplatin to Treat Head and Neck Cancer
Status: COMPLETED
Conditions: Carcinoma, Squamous|Head and Neck Cancer|Oral Cancer|Laryngeal Cancer|Pharyngeal Cancer
Interventions: DRUG: Bortezomib (Velcade, PS-341)|DRUG: Cetuximab|DRUG: Cisplatin|PROCEDURE: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT