pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Low-level Laser Therapy With a 635nm Diode Laser on Orthodontic Mini-implants Stability.
Status: COMPLETED
Conditions: Malocclusion, Angle Class II
Interventions: PROCEDURE: Irradiation of implants with 635nm laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Hypertension in Left Heart Disease
Status: RECRUITING
Conditions: Pulmonary Hypertension|Pulmonary Vascular Disease|Left Heart Disease
Interventions: DIAGNOSTIC_TEST: Transthoracic Echocardiography (TTE)|DIAGNOSTIC_TEST: Lung ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SUCCEED Africa: Support, Comprehensive Care and Empowerment of People With Psychosocial Disabilities
Status: RECRUITING
Conditions: Schizophrenia|Schizoaffective Disorder|Schizotypal Disorder|Acute and Transient Psychotic Disorder|Delusional Disorder|Other Specified or Unspecified Primary Psychotic Disorder|Bipolar Type I Disorder With Psychotic Symptoms|Bipolar Type II Disorder With Psychotic Symptoms|Single Episode Depressive Disorder With Psychotic Symptoms|Recurrent Depressive Disorder With Psychotic Symptoms|Perinatal Mental or Behavioural Disorder With Psychotic Symptoms
Interventions: BEHAVIORAL: SUCCEED Community-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ultrasound-guided Nerve Block Training Model and Evaluation Method
Status: NOT_YET_RECRUITING
Conditions: Nerve Blocks|Medical Education, Simulation, Crisis Resource Management|Medical Education in Emergency Ultrasound
Interventions: BEHAVIORAL: ultrasound education and simulation workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PRP Versus Saline in Lateral Epicondylitis
Status: UNKNOWN
Conditions: Lateral Epicondylitis, Unspecified Elbow
Interventions: BIOLOGICAL: Platelet rich plasma injection|OTHER: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of a Training Intervention for Pulmonary Embolism Diagnosis in Emergency Department (APEED)
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: BEHAVIORAL: Training Intervention for PE Diagnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: LifeVest Post-CABG Registry
Status: TERMINATED
Conditions: Sudden Cardiac Death|Ventricular Fibrillation|Ventricular Tachycardia|Ventricular Dysfunction|Myocardial Ischemia
Interventions: DEVICE: wearable defibrillator (LifeVest)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability, Pharmacokinetics and Efficacy of LMB763 in Patients With NASH
Status: TERMINATED
Conditions: Non-alcoholic Steatohepatitis NASH
Interventions: DRUG: LMB763|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Male Partner-assisted Contact Tracing for HIV and Tuberculosis in Malawi
Status: TERMINATED
Conditions: Tuberculosis
Interventions: OTHER: Access to Fast Track TB clinic|OTHER: Information leaflet for male partner|OTHER: Home sputum collection|OTHER: Home HIV testing|OTHER: Financial incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: AuraClens™ System in Processing of Lipoaspirate for Autologous Fat Grafting to the Breast
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Fat Grafting Retention
Interventions: DEVICE: AuraGen 1-2-3 with AuraClens
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MIL62 in Treatment of CD20 Positive B-cell Lymphomas
Status: COMPLETED
Conditions: CD20-positive B Cell Non-Hodgkin Lymphoma
Interventions: DRUG: Recombinant Humanized Monoclonal Antibody MIL62 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extended Administration of Polyethylene Glycol (PEG) Interferon Alfa-2b in Participants With Solid Tumors (C/I97-349/MK-4031-009)
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: PEG Interferon Alfa-2b|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene Expression Outcomes in Interventions for Substance Using HIV+ Minority Men
Status: COMPLETED
Conditions: Human Immunodeficiency Virus Infection|Inflammation
Interventions: BEHAVIORAL: AWARENESS for Sexual Minorities|BEHAVIORAL: Writing tasks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Oral Dosing of ASP0456 in Patients With Chronic Constipation
Status: COMPLETED
Conditions: Chronic Constipation
Interventions: DRUG: linaclotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CMX001 to Prevent/Control Cytomegalovirus Infection in R+ Hematopoietic Stem Cell Transplant Recipients
Status: COMPLETED
Conditions: Cytomegalovirus Infection
Interventions: DRUG: Brincidofovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: GlideScope Groove vs. Standard GlideScope: A Non-inferiority Study
Status: WITHDRAWN
Conditions: Intubation, Orotracheal
Interventions: DEVICE: GlideScope Groove|DEVICE: Control: Standard GlideScope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of the Potent CYP3A4 Inhibitor Itraconazole on the Pharmacokinetics (PK) of TAK-906 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: TAK-906 Maleate|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase I Study of 131-I mIBG Followed by Nivolumab & Dinutuximab Beta Antibodies in Children With Relapsed/Refractory Neuroblastoma
Status: RECRUITING
Conditions: Neuroblastoma
Interventions: DRUG: Nivolumab|DRUG: Ch14.18/CHO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Long-term Outcomes After Two Different Anaesthetics
Status: ACTIVE_NOT_RECRUITING
Conditions: Anesthesia|Neurotoxicity|Child Development
Interventions: DRUG: Sevoflurane|DRUG: Remifentanil|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy, Safety And Tolerability Study of Flexibly Dosed Paliperidone Extended-Release (ER) in Participants With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron Study of Neonates Iron Study of Neonates Birth in Assuit University Children's Hospital
Status: UNKNOWN
Conditions: Iron Study of Neonates: Factors Affecting and Impact on Their Health Status at Birth in Assuit University Children's Hospital
Interventions: DIAGNOSTIC_TEST: Iron study of neonates
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nebulized Ceftazidime and Amikacin in Ventilator Associated Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: ceftazidime and amikacin|DRUG: ceftazidime and amikacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Female Microbiome in Patients Undergoing Bladder Instillation Therapy
Status: COMPLETED
Conditions: Interstitial Cystitis|Bladder Pain Syndrome|Microbial Colonization
Interventions: DRUG: Heparin & Alkalinized Lidocaine Bladder Instillation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparative Study of Anterior vs. Posterior Surgical Treatment for Lumbar Isthmic Spondylolisthesis
Status: COMPLETED
Conditions: Isthmic Spondylolisthesis
Interventions: PROCEDURE: Anterior Lumbar Interbody Fusion (ALIF)|PROCEDURE: Posterior Fusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect and Experience of the Parental Program AFFEKT
Status: RECRUITING
Conditions: Behavior, Child|Parenting|Parent-Child Relations|Stress|Quality of Life
Interventions: BEHAVIORAL: AFFEKT - a manual based brief parent program for parents of children (aged 6-12 years) with externalizing behaviors.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Adherence to Closed Face Shields to Prevent COVID-19 Transmission
Status: COMPLETED
Conditions: SARS-CoV-2 Infection
Interventions: OTHER: Closed face shield with Surgical face mask use|OTHER: Surgical face mask use only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial Evaluating the Efficacy of the Combination of ROpivacaine With Reference XYlocaine in the Evaluation of Pain During the Installation of Percutaneous Radiological GASTrostomy
Status: TERMINATED
Conditions: Cancer|Feeding Disorders
Interventions: DRUG: Lidocaine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Evaluation of Prebiotics Combined With Quadruple Probiotics in Improving Functional Constipation.
Status: ENROLLING_BY_INVITATION
Conditions: Functional Constipation
Interventions: COMBINATION_PRODUCT: Take prebiotics and probiotics|BEHAVIORAL: lifestyle guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of FURESTEM-AD Inj. in Patients With Moderately Subacute and Chronic Atopic Dermatitis (AD)
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: FURESTEM-AD Inj.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROSTVAC (PSA-TRICOM) in Preventing Disease Progression in Patients With Localized Prostate Cancer Undergoing Active Surveillance
Status: COMPLETED
Conditions: Stage I Prostate Adenocarcinoma AJCC v7|Stage II Prostate Adenocarcinoma AJCC v7
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Placebo Administration|BIOLOGICAL: Rilimogene Galvacirepvec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Retinal Neurovascular Coupling in Patients Previously Infected With COVID-19
Status: RECRUITING
Conditions: COVID-19|Post-COVID-19 Syndrome
Interventions: DEVICE: Dynamic Vessel Analyzer (DVA)|DEVICE: Fourier domain optical coherence tomography (FDOCT)|DEVICE: Optical coherence tomography (OCT)|DEVICE: Laser Speckle Flowgraphy (LSFG)|DIAGNOSTIC_TEST: Proteomics and Metabolites in Plasma, tear fluid and finger sweat
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Cold Dry Air Exposure, Discs and Capsaicin
Status: UNKNOWN
Conditions: Nasal Hyper Reactivity
Interventions: OTHER: cold dry air|DEVICE: hyperosmolar discs|DEVICE: capsaicin nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Breakfast for Young Females
Status: COMPLETED
Conditions: Overweight and Obesity|Overweight Adolescents|Metabolic Disease
Interventions: DIETARY_SUPPLEMENT: Low protein breakfast|DIETARY_SUPPLEMENT: High protein breakfast|OTHER: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study of 9MW2821 (and PD-1 Inhibitor) in Locally Advanced or Metastatic Triple-Negative Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Triple-Negative Breast Cancer
Interventions: DRUG: 9MW2821|DRUG: PD-1 inhibitior
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Single Intravenous (IV) Dose of MK-3402 in Participants With Impaired Renal Function and in Healthy Controls (MK-3402-004)
Status: TERMINATED
Conditions: Renal Impairment
Interventions: DRUG: MK-3402
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluorine-18-AlphaVBeta6-Binding Peptide Positron Emission Tomography in Metastatic Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer|Lung Cancer Metastatic|Brain Metastases|Non Small Cell Lung Cancer
Interventions: DRUG: [18F]-αvβ6-BP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of rTMS Personalized Precision Treatment of Post-stroke Depression
Status: UNKNOWN
Conditions: Post-stroke Depression
Interventions: DEVICE: "personalized" rTMS+drug treatment|DEVICE: Traditional rTMS +drug treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intra Operative Dexmedetomidine in Prevention of Early Postoperative Atrial Fibrillation
Status: UNKNOWN
Conditions: Postoperative Atrial Fibrillation
Interventions: DRUG: Intra Operative Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ixazomib Plus Low-dose Lenalidomide Versus Ixazomib Alone for Maintenance Treatment of High Risk Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Ixazomib plus low-dose lenalidomide|DRUG: Ixazomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the PelvicSim Simulator for Training in Intrauterine Device Insertions
Status: COMPLETED
Conditions: Contraceptive Devices, Intrauterine|Education, Medical
Interventions: OTHER: PelvicSim|DEVICE: Manufacturer model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combination Chemotherapy and Thalidomide in Treating Younger Patients Undergoing Surgery For Newly Diagnosed Liver Cancer
Status: UNKNOWN
Conditions: Liver Cancer
Interventions: DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: thalidomide|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Artificial Sweeteners (AFS) on Sweetness Sensitivity, Preference and Brain Response in Adolescents
Status: TERMINATED
Conditions: Insulin Resistance|Obesity
Interventions: DIETARY_SUPPLEMENT: Sucralose|DIETARY_SUPPLEMENT: Sucrose|DIETARY_SUPPLEMENT: Sucralose + maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intra-articular Bevacizumab for Recurrent Hemarthroses at Target Joints With Chronic Hemophilic Synovitis
Status: TERMINATED
Conditions: Hemophilia|Synovitis
Interventions: DRUG: Bevacizumab intra-articular injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diltiazem Gel Versus Nitroglycerin Ointment in Healing Process of Scleroderma Digital Ulcers
Status: COMPLETED
Conditions: Digital Ulcer of Scleroderma
Interventions: DRUG: Diltiazem Gel 2%|DRUG: Nitroglycerin Ointment 2%|DRUG: Vaseline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Renew NCP-5 for the Treatment of Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild Dementia of the Alzheimer's Type
Status: COMPLETED
Conditions: Alzheimer Disease|Cognitive Dysfunction|Mild Cognitive Impairment|Mild Dementia|Cognitive Decline|Dementia, Alzheimer Type
Interventions: DEVICE: Renew NCP-5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protein Blends (Soy, Whey and Casein) for Muscle Synthesis
Status: COMPLETED
Conditions: Muscle Synthesis
Interventions: OTHER: Protein Blend
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Random Evaluation of Patients Who Have Had Laparoscopic Partial Nephrectomy
Status: RECRUITING
Conditions: Kidney Cancer
Interventions: DEVICE: Hemostatic Agent|OTHER: No Hemostatic Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Saquinavir/Ritonavir in Single Therapy as Maintenance Treatment
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Saquinavir/Ritonavir : 2 capsules (500 mg) / 12 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Efficacy and Safety of GZR101 and IDegAsp in Insulin Naïve or Insulin Treated Subjects With T2DM
Status: ENROLLING_BY_INVITATION
Conditions: Type 2 Diabetes
Interventions: DRUG: GZR101|DRUG: insulin degledec/insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Assessment of Niacinamide Cosmetic Preparation: a Randomized Controlled Trial
Status: RECRUITING
Conditions: Skin Hyperpigmentation|Dry Skin; Eczema
Interventions: OTHER: miss alice face it you love me serum|OTHER: No treatment (usual skincare rutine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carbetocin Versus Syntometrine for the Third Stage of Labour
Status: COMPLETED
Conditions: Postpartum Haemorrhage
Interventions: DRUG: Syntommetrine and Carbetocin|DRUG: Syntommetrine and Carbetocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Essential Coaching for Every Mother in Tanzania
Status: RECRUITING
Conditions: Parenting Self Efficacy|Postpartum Depression|Postpartum Anxiety|Breastfeeding Self-Efficacy|Newborn Knowledge
Interventions: BEHAVIORAL: Essential Coaching for Every Mother
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fit For Function: A Community Wellness Program for Persons With Stroke
Status: COMPLETED
Conditions: Cerebrovascular Accident
Interventions: OTHER: Fit For Function Program|OTHER: Standard YMCA membership
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intrathecal Dexmedetomidine Versus Transversus Abdominus Plane Block (TAP) for Postoperative Analgesia After Cesarean Section.
Status: COMPLETED
Conditions: Pain Management in Adult Females in Child Bearing Period Aging From 20 to 45 Years Who Are Scheduled for Elective Cesarean Section
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pectointercostal Fascial Plane Block Versus Transversus Thoracic Plane Block In Adult Cardiac Surgery Patients
Status: UNKNOWN
Conditions: Pain, Post Operative
Interventions: PROCEDURE: ultrasound guided regional block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Manual Therapy and Dry Needling in Patellofemoral Syndrome
Status: COMPLETED
Conditions: Patellofemoral Syndrome
Interventions: OTHER: Manual therapy|DEVICE: Dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Buffered Anesthetic Solution in the Treatment of Mandibular Primary Molars
Status: COMPLETED
Conditions: Local Anesthesia
Interventions: COMBINATION_PRODUCT: Buffered lidocaine in inferior alveolar nerve block injection|DRUG: lidocaine 2% in inferior alveolar nerve block injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of JV-GL1 in Patients With Open-Angle Glaucoma or Ocular Hypertension
Status: SUSPENDED
Conditions: Ocular Hypertension|Open Angle Glaucoma
Interventions: DRUG: JV-GL1|DRUG: Latanoprost 0.005% Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aquamin® as an Adjuvant Intervention for Ulcerative Colitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Aquamin®|DRUG: Placebo first then Aquamin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Timing of Invasive Intracranial Pressure Monitoring Between Neurosurgeons and Intensive Care Physicians
Status: UNKNOWN
Conditions: Intracranial Hypertension|Timing of Invasive Intracranial Pressure Monitoring
Interventions: OTHER: Time necessary for ICP catheter placement by Intensive Care Physician vs Neurosurgeon following indication
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of S-1 and Oxaliplatin as Neoadjuvant Chemotherapy for Locally Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Drug: S-1 and oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Ethinylestradiol/Drospirenone in Dysmenorrhea
Status: COMPLETED
Conditions: Dysmenorrhea
Interventions: DRUG: DRSP 3 mg/EE 20 µg (13 cycles)|DRUG: DRSP 3 mg/EE 30 µg (6 cycles)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Functional Test for a Drink Powder Alone and Combined Use With a Cosmetic Apparatus
Status: COMPLETED
Conditions: Beauty Drink Powder|Cosmetic Apparatus on Skin|Skin Elasticity|Skin Dryness|Skin Moisture|Skin Evenness|Skin Firmness
Interventions: DIETARY_SUPPLEMENT: Beauty drink powder|DEVICE: Cosmetic apparatus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Telitacicept in the Treatment of Systemic Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Diffuse Cutaneous Systemic Sclerosis
Interventions: DRUG: Telitacicept|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triple Versus Quadruple Therapy for the Eradication of Helicobacter Pylori
Status: NOT_YET_RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Vonoprazan-Amoxicillin-Tetracycline-Bismuth quadruple regimen for 14 days|DRUG: Vonoprazan-Amoxicillin-Tetracycline triple regimen for 14 days|DRUG: Vonoprazan-Amoxicillin-Tetracycline triple regimen for 7 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study to Examine the Effect of Coated Nifedipine Suppositories on Anal Pressure in Healthy Subjects
Status: COMPLETED
Conditions: Anal Resting Pressure
Interventions: DRUG: Coated Nifedipine Suppositories
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose:
Clinical trial: Reslizumab to Prevent Post-treatment Eosinophilia in Loiasis
Status: COMPLETED
Conditions: Loiasis
Interventions: DRUG: Reslizumab|DRUG: Diethylcarbamazine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Marizomib Central Nervous System (CNS)
Status: WITHDRAWN
Conditions: Multiple Myeloma|Multiple Myeloma in Relapse|Multiple Myeloma, Refractory
Interventions: DRUG: Marizomib|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Re-licensing Study to Assess the Efficacy of Inflexal V Formulated With WHO Recommended 2010/2011 Influenza Virus Strains for the Northern Hemisphere
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Inflexal V
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Confirmatory Study of TAU-284 in Pediatric Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis|Atopic
Interventions: DRUG: Bepotastine besilate|DRUG: ketotifen fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Total Therapy Study XIV for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia
Status: TERMINATED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Prednisone, Dexamethasone, Vincristine, Daunorubicin, PEG-L-asparaginase|DRUG: L-asparaginase, Methotrexate, Idarubicin, Etoposide, Cyclophosphamide, Cytarabine, Mercaptopurine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Counseling Program for Temporomandibular Disorders (TMD) Treatment
Status: COMPLETED
Conditions: Temporomandibular Disorders
Interventions: BEHAVIORAL: Counseling|DEVICE: Interocclusal Appliances
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decreasing Leak Rate in Colorectal Surgery Using Near Infra-red (NIR) Imaging
Status: COMPLETED
Conditions: Anastomotic Leak
Interventions: PROCEDURE: NIR anastomotic perfusion assessment|DEVICE: Near infrared camera
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Misoprostol for NASH
Status: COMPLETED
Conditions: NASH
Interventions: DRUG: Misoprostol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Moderate-to-vigorous Physical Activity for Glycemic Control in Patients With Gestational Diabetes Mellitus
Status: TERMINATED
Conditions: Gestational Diabetes Mellitus|Exercise
Interventions: BEHAVIORAL: Moderate-to-vigorous intensity exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SUVN-502 With Donepezil and Memantine for the Treatment of Moderate Alzheimer's Disease- Phase 2a Study
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: SUVN-502|DRUG: Placebo|DRUG: Donepezil|DRUG: Memantine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant RCT Versus CT for Patients With Locally Advanced, Potentially Resectable Adenocarcinoma of the GEJ
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: 5-Fluorouracil|DRUG: Calcium folinate|DRUG: Oxaliplatin|DRUG: Docetaxel|RADIATION: Radiation|DRUG: Oxaliplatin during radiotherapy|DRUG: 5-Fluorouracil during radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quetiapine Fumarate (SEROQUEL) in the Treatment of Adolescent Patients With Schizophrenia and Bipolar I Disorder
Status: COMPLETED
Conditions: Schizophrenia|Bipolar I Disorder
Interventions: DRUG: quetiapine fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quadratus Lumborum Versus Transversus Abdominis Plane Block Versus Caudal Block for Postoperative Analgesia After Pediatric Inguinal Hernia : Double-Blinded Randomized Trial
Status: UNKNOWN
Conditions: Quadratus Lumborum Block|Transversus Abdominis Plane Block|Caudal Block|Postoperative Pain|Inguinal Hernia
Interventions: DRUG: propofol|DRUG: Atracurium Besylate|DRUG: sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Veliparib, Oxaliplatin, and Capecitabine in Treating Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Adenocarcinoma of the Pancreas|Adenocarcinoma of the Stomach|BRCA1 Mutation Carrier|BRCA2 Mutation Carrier|Ovarian Mucinous Cystadenocarcinoma|Recurrent Breast Cancer|Recurrent Colon Cancer|Recurrent Gastric Cancer|Recurrent Ovarian Epithelial Cancer|Recurrent Ovarian Germ Cell Tumor|Recurrent Pancreatic Cancer|Recurrent Rectal Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer|Stage IV Colon Cancer|Stage IV Gastric Cancer|Stage IV Ovarian Epithelial Cancer|Stage IV Ovarian Germ Cell Tumor|Stage IV Pancreatic Cancer|Stage IV Rectal Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: veliparib|DRUG: capecitabine|DRUG: oxaliplatin|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NATRELLE® 410 Full and Moderate Height/Projection Breast Implant Continued Access Post-Approval Study
Status: TERMINATED
Conditions: Breast Augmentation|Breast Reconstruction|Breast Implant Revision
Interventions: DEVICE: Anatomically shaped silicone gel-filled breast implants
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Postoperative Cognitive Function in Patients With Sevoflurane Postconditioning on Carotid Intima Stripped
Status: UNKNOWN
Conditions: Postoperative Cognitive Dysfunction|Sevoflurane|Carotid Artery Intima Stripped
Interventions: DRUG: Sevoflurane inhalant product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: CAPABLE Transplant
Status: NOT_YET_RECRUITING
Conditions: Quality of Life|Depression|End Stage Renal Disease|Disability Physical
Interventions: BEHAVIORAL: CAPABLE Transplant- Open Label Pilot|BEHAVIORAL: CAPABLE Transplant- Randomized Control Trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Topical Nepafenac in Macular Thickening Related to Pan-retinal Photocoagulation
Status: TERMINATED
Conditions: Macular Thickening|Macular Edema
Interventions: DRUG: Nepafenac|OTHER: Lubricant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Plecanatide in Children 6 to <18 Years of Age With Irritable Bowel Syndrome With Constipation (IBS-C)
Status: RECRUITING
Conditions: Irritable Bowel Syndrome With Constipation
Interventions: DRUG: Plecanatide|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of an HIV Preventive Vaccine Given With or Without an Adjuvant in HIV Uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: HIV-1 gag DNA|BIOLOGICAL: HIV-1 gag DNA plus IL-12 DNA adjuvant|BIOLOGICAL: CTL MEP/RC529-SE/GM-CSF (CTL MEP vaccine)|BIOLOGICAL: Sodium chloride injection (0.9%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Poly ICLC, and IDO1 Inhibitor INCB024360 in Treating Patients With Ovarian, Fallopian Tube, or Primary Peritoneal Cancer in Remission
Status: COMPLETED
Conditions: Fallopian Tube Carcinoma|Ovarian Carcinoma|Primary Peritoneal Carcinoma
Interventions: BIOLOGICAL: DEC-205/NY-ESO-1 Fusion Protein CDX-1401|DRUG: Epacadostat|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Poly ICLC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suprascapular Nerve Block Versus Intraarticular Steroid Injection in Hemiplegic Shoulder Pain
Status: UNKNOWN
Conditions: Hemiplegic Shoulder Pain
Interventions: PROCEDURE: Suprascapular nerve block (SSNB)|PROCEDURE: Intraarticular shoulder steroid injection (IAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Care Clinical Practice Elements and Improving Overweight Children's Weight Status
Status: COMPLETED
Conditions: Overweight|Childhood Obesity
Interventions: OTHER: Attention to BMI|OTHER: Attention to high-BMI-related Medical Risk|OTHER: No attention to high BMI or high-BMI-related medical risk
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevention of Sagopilone-induced Neurotoxicity With Acetyl-L-Carnitine (ALC)
Status: COMPLETED
Conditions: Prostate Cancer|Ovarian Cancer
Interventions: DRUG: Sagopilone 16 mg/m^2 i.v., Acetyl-L-Carnitine (ALC) 1000 mg tid, HRPC only: Prednisone or Prednisolone 5 mg bid|DRUG: Sagopilone 16 mg/m^2 i.v. and placebo 1000 mg tid, HRPC only: Prednisone or Prednisolone 5 mg bid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Revised Algorithm for Next Generation DeVilbiss Healthcare AutoAdjust Continuous Positive Airway Pressure (CPAP)
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: DeVilbiss AutoAdjust CPAP with revised algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Erosive Osteoarthritis of the Hands: Treatment by Methotrexate Versus Placebo
Status: UNKNOWN
Conditions: Polyarthritis
Interventions: DRUG: Methotrexate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sodium Oligomannate in the Prevention of PSCI
Status: NOT_YET_RECRUITING
Conditions: Ischemic Stroke
Interventions: DRUG: Sodium oligomannate|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transcranial Direct Current Stimulation (tDCS) Cost-utility-analysis in Medical Care on Depressive Episode With One Drug Therapy Failure.
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression
Interventions: OTHER: tDCS associated with usual care|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interleukin-12 and Interleukin-2 in Treating Patients With Refractory or Recurrent Neuroblastoma
Status: TERMINATED
Conditions: Recurrent Neuroblastoma
Interventions: BIOLOGICAL: recombinant interleukin-12|BIOLOGICAL: aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monitoring Brain Activity in Human Brain Injury
Status: UNKNOWN
Conditions: Traumatic Brain Injury|Aneurysmal Subarachnoid Hemorrhage|Cerebral Infarction|Cerebral Hemorrhage
Interventions: PROCEDURE: Procedure: intracranial monitoring up to 9 days after injury
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 3 Study of Nivolumab or Nivolumab Plus Ipilimumab Versus Ipilimumab Alone in Previously Untreated Advanced Melanoma (CheckMate 067)
Status: COMPLETED
Conditions: Unresectable or Metastatic Melanoma
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Placebo for Nivolumab|BIOLOGICAL: Placebo for Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Port Site Bupivacaine Injection in Postoperative Pain Reduction After Lap. Chole
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: 0.25% Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictors of Probabilistic Selection Task Performance
Status: UNKNOWN
Conditions: Learning; Lack of (Specific)
Interventions: BEHAVIORAL: Effects of tDCS of dlPFC on Probabilistic Selection Task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Uremic Hyperhomocysteinemia -A Folate Trial for Possible Prevention of Cardiovascular Events
Status: COMPLETED
Conditions: Uremia|Chronic Renal Failure|Hemodialysis|Hyperhomocysteinemia|Cardiovascular Disease
Interventions: DRUG: folate treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Septal Mapping And Resynchronisation Therapy- (SMART) Study
Status: COMPLETED
Conditions: Cardiac Resynchronization Therapy|Heart Failure
Interventions: DEVICE: Cardiac resynchronization therapy by CRT-P or CRT-D implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Improving Negative Stressful Perseverations in Insomnia to Revitalize Expectant Moms
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia (CBTI)|BEHAVIORAL: Perinatal-enhanced Behavioral Therapy for Insomnia|BEHAVIORAL: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AI Algorithms to Automate the TMI by VMAT Optimization Using WB-CT/MRI and Synthetic WB-CT - The AuToMI Project
Status: UNKNOWN
Conditions: Hematological Disease
Interventions: RADIATION: Total Marrow (Lymph-node) Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 2 Trial of Mosunetuzumab and Zanubrutinib for Patients With Relapsed/Refractory Marginal Zone Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Lymphoma
Interventions: DRUG: Mosunetuzumab|DRUG: Zanubrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Ursodeoxycholic Acid (UDCA) for Parkinson's Disease: The "UP" Study
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Ursonorm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: CAPOX and PD-1 Antibody Combined With or Without Radiotherapy for MSS Locally Advanced Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Rectal Cancer|Neoadjuvant Therapy
Interventions: DRUG: PD-1 antibody|DRUG: Capecitabine|RADIATION: Short-course radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In-Vitro Studies in Depletion of Haplotype Mismatched Alloreactive T Cells
Status: WITHDRAWN
Conditions: Hematologic Malignancies|Hematopoietic Stem Cell Transplantation
Interventions: PROCEDURE: collection of peripheral blood and apheresis samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Bioequivalence Study Of Ethinylestradiol + Gestodene In Female And Healthy Volunteers.
Status: COMPLETED
Conditions: Bioequivalence|Ethinylestradiol|Gestodene|Harmonet
Interventions: DRUG: Reference Drug|DRUG: Test Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Safety and Efficacy Study of a Recombinant and Protein-Free Factor VIII (rAHF-PFM) in Hemophilia A Patients Undergoing Surgery
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: Antihemophilic factor, recombinant, manufactured protein-free
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor Stem Cell Transplantation Using α/β+ T-lymphocyte Depleted Grafts From HLA Mismatched Donors
Status: TERMINATED
Conditions: Acute Lymphoid Leukemia (ALL)|Acute Myeloid Leukemia (AML)|Chronic Myeloid Leukemia (CML)|Hodgkin Lymphoma|Non-Hodgkin Lymphoma|Chronic Lymphocytic Leukemia
Interventions: RADIATION: Hyperfractionated total body irradiation|DRUG: Thiotepa|DRUG: Cyclophosphamide|DRUG: Busulfan|DRUG: Fludarabine|DRUG: Melphalan|DRUG: Clofarabine|PROCEDURE: HPC(A) stem cell allograft|DRUG: Rituximab|DEVICE: Rabbit antithymocyte globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Extension Study to Evaluate Long-term Safety of Sacubitril/Valsartan in Pediatric Patients With HF
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: sacubitril/valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whey Protein Pre-load and Postprandial Glycemia in Pregnancy
Status: RECRUITING
Conditions: Pregnancy|Postprandial Glycemia
Interventions: DIETARY_SUPPLEMENT: Whey protein-preload OGTT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of HR17031 Injection With Hepatic Insufficiency
Status: UNKNOWN
Conditions: Improved Glycemic Control in Patients With Type 2 Diabetes
Interventions: DRUG: HR17031 injection|DRUG: HR17031 injection|DRUG: HR17031 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of QLG1074 Combined With Background Therapy in Subjects With Active Lupus Nephritis
Status: RECRUITING
Conditions: Lupus Nephritis
Interventions: DRUG: Voclosporin（QL1074）|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Status Assessment In Elderly Patients With Active Treatment For Haematological Malignancies
Status: UNKNOWN
Conditions: Cognitive Impairment|Haematological Malignancy|Chemo-brain
Interventions: OTHER: Cognitive Assessment, Cytokine dosage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: High Inspiratory Oxygen Fraction on Endothelial Function in Healthy Volunteers
Status: COMPLETED
Conditions: Endothelial Dysfunction
Interventions: OTHER: 80% oxygen|OTHER: 30% oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ph. II Treatment of Adults w Primary Malignant Glioma w Irinotecan + Temozolomide
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: Temodar and Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT