pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Thykamine Safety and Efficacy Study in Mild-to-Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis Eczema
Interventions: DRUG: Administration of Placebo|DRUG: Administration of PUR0110 (Thykamine) 0.05%|DRUG: Administration of PUR0110 (Thykamine) 0.1%|DRUG: Administration of PUR0110 (Thykamine) 0.25%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Minocycline and Armodafinil for Reducing the Symptom Burden Produced by Chemoradiation Treatment for Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: Armodafinil|OTHER: Placebo|DRUG: Minocycline|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Real-world Evaluation of Brolucizumab for the Treatment of Neovascular (Wet) Age-related Macular Degeneration (AMD) (Komodo Health)
Status: COMPLETED
Conditions: Age-related Macular Degeneration (AMD)
Interventions: DRUG: Brolucizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety and Efficacy of PLM60 in Advanced HCC
Status: UNKNOWN
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: Liposome-entrapped Mitoxantrone Hydrochloride Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics on Oral Candida Among Denture Wearers
Status: ACTIVE_NOT_RECRUITING
Conditions: Oral Candida Albicans Infection
Interventions: OTHER: Probiotic group|OTHER: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Move it, Move ID! Promotion of Physical Activity in Adolescents With Intellectual Disability
Status: COMPLETED
Conditions: Physical Activity|Health Promotion|Adolescents|Intellectual Disability
Interventions: BEHAVIORAL: theory-based mHealth-intervention (app)|BEHAVIORAL: theory-based mHealth-intervention (app)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Person-Environment Fit for Persons With Dementia
Status: RECRUITING
Conditions: Dementia Alzheimers|Alzheimer Disease
Interventions: BEHAVIORAL: Harmony at HOME|BEHAVIORAL: National Institute on Aging Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ten Year Implant Survivorship of the ANTHEM™ PS Total Knee System
Status: ACTIVE_NOT_RECRUITING
Conditions: Arthroplasty, Replacement, Knee
Interventions: DEVICE: ANTHEM™ PS Total Knee System implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration (REALIST)
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Respiratory Distress Syndrome
Interventions: BIOLOGICAL: Human umbilical cord derived CD362 enriched MSCs|BIOLOGICAL: Placebo (Plasma-Lyte 148)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Central Compartment Neck Dissection With Thyroidectomy
Status: TERMINATED
Conditions: Indeterminate Thyroid Nodules
Interventions: PROCEDURE: Total Thyroidectomy + CLND|PROCEDURE: Total thyroidectomy - CLND|PROCEDURE: Hemi-thyroidectomy + CLND|PROCEDURE: Hemi-thyroidectomy - CLND
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluates the Effects of Electroacupuncture for Postoperative Pain Relief in Patients With Repair for TFCC Tears
Status: UNKNOWN
Conditions: Postoperative Pain Relief
Interventions: OTHER: electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Closed and Open Kinetic Chain Exercises
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: OTHER: Closed Cinetic Chain Exercises|OTHER: Open Kinetic Chain Exercises|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility and Safety Study of Intratumoral Diffusing Alpha Radiation Emitters for the Treatment of Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer|Unresectable Pancreatic Cancer|Metastatic Pancreatic Cancer|Pancreatic Adenocarcinoma
Interventions: DEVICE: Radiation: Diffusing Alpha Radiation Emitters Therapy (DaRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of STP0404 in Adults With HIV-1 Infection
Status: RECRUITING
Conditions: HIV-1-infection
Interventions: DRUG: Low-dose STP0404 (Pirmitegravir)|DRUG: Medium-dose STP0404 (Pirmitegravir)|DRUG: High-dose STP0404 (Pirmitegravir)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Clinical Trial of Safety and Efficacy of Daily Application of Topical Dutasteride in Men With Androgenic Alopecia.
Status: ACTIVE_NOT_RECRUITING
Conditions: Male Androgenetic Alopecia
Interventions: DRUG: Dutasteride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pregabalin Open-Label Extension Trial in Patients With Partial Seizures
Status: COMPLETED
Conditions: Epilepsies, Partial|Epilepsy, Complex Partial
Interventions: DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Ligelizumab in Chronic Spontaneous Urticaria Patients Who Completed a Previous Study With Ligelizumab
Status: TERMINATED
Conditions: Chronic Spontaneous Urticaria
Interventions: DRUG: Ligelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NRM on Vascular Perfusion in Healthy Adults
Status: NOT_YET_RECRUITING
Conditions: Vascular Stiffness
Interventions: DIETARY_SUPPLEMENT: Nicotinamide Riboside Malate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ph II Erlotinib + Sirolimus for Pts w Recurrent Malignant Glioma Multiforme
Status: COMPLETED
Conditions: Glioblastoma|Gliosarcoma
Interventions: DRUG: Erlotinib + sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Low Level Laser Therapy to Treat Chronic Heel Pain Arising From Plantar Fasciitis
Status: COMPLETED
Conditions: Plantar Fasciitis
Interventions: DEVICE: Erchonia HPS Laser|DEVICE: Placebo Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Regorafenib in Metastatic Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: Regorafenib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of 12 Month Daily Wear of Two Novel O2 Permeable Silicone Hydrogel CLs (HOP/SiH) and A Control, Standard O2 Lens
Status: COMPLETED
Conditions: Contact Lenses, Extended-Wear
Interventions: DEVICE: Silicone Hydrogel Soft Contact Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Safety and Efficacy of Medtronic Extended Mio 30 Infusion Set
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Medtronic Extended Mio 30 Infusion Set
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3454738 in Healthy Participants and Participants With Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: LY3454738|DRUG: LY3454738|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use Of SB424323 With Aspirin In Non-Valvular Atrial Fibrillation In Patients At A Low Or Intermediate Risk For Stroke
Status: COMPLETED
Conditions: Fibrillation, Atrial|Atrial Fibrillation
Interventions: DRUG: SB424323
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: An Intervention to Improve Management of Dyslipidemia in Primary Care
Status: UNKNOWN
Conditions: Cardiovascular Disease|Dyslipidemia|Diabetes Melletus|Obesity
Interventions: OTHER: Audit|OTHER: Physician Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Patient Outcomes Associated With Two Accelerated Method of Retraction of Upper Front Teeth
Status: COMPLETED
Conditions: Class II Division 1 Malocclusion
Interventions: PROCEDURE: Traditional corticotomy|PROCEDURE: Flapless corticotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Efficacy of UB-421 Antibody in HIV-1 Infected Adults
Status: COMPLETED
Conditions: HIV-1 Infection in Adults
Interventions: DRUG: Antibody UB-421
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Systemic Valacyclovir (Valtrex) on Periodontitis
Status: RECRUITING
Conditions: Severe Periodontitis
Interventions: DRUG: Valacyclovir group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Pharmacokinetics, and Pharmacodynamics of a Single Dose of SAR438544 in Comparison to Glucagon in Type 1 Diabetes Mellitus Patients Under Induced Hypoglycemia
Status: WITHDRAWN
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: SAR438544|DRUG: r-glucagon|DRUG: insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Study of a New Medical Food in the Management of Ulcerative Colitis
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: Soluble protein hydrolysate (SPHi)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Single Intravenous Dose, Parallel Phase I Clinical Study to Compare the Pharmacokinetic Characteristics, Safety, and Immunogenicity of HLX05 Vs. Erbitux® (Cetuximab) in Healthy Adult Male Chinese Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: EGFR Overexpression
Interventions: DRUG: recombinant anti-EGFR human/murine chimeric monoclonal antibody injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MK-6598 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-6598-001)
Status: RECRUITING
Conditions: Advanced or Metastatic Solid Tumors
Interventions: DRUG: MK-6598|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Pramipexole Extended Release (PPX ER) 1.5mg x 1 Tablet Once Daily (q.d.) vs. PPX ER 0.375mg x 4 Tablets Under Fasted and Fed Conditions in Japanese Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PPX ER|DRUG: PPX ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Implementation Research to Increase Colorectal Cancer Screening Rates Among Low Income and Ethnic Minority Groups
Status: RECRUITING
Conditions: Colorectal Carcinoma
Interventions: OTHER: Best Practice|OTHER: Consultation|OTHER: Educational Intervention|OTHER: Electronic Health Record Review|OTHER: Fecal Immunochemical Test|BEHAVIORAL: Feedback|BEHAVIORAL: Health Education|OTHER: Support Education Activity|OTHER: Text Message-Based Navigation Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Clinical Study of Epoetin Beta to Chemotherapy-Induced Anemia (CIA) Patients
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: epoetin beta|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Inhalation of Essential Oil on the Reduction of Inhalants Craving
Status: COMPLETED
Conditions: Inhalants Craving
Interventions: COMBINATION_PRODUCT: Essential oil|COMBINATION_PRODUCT: Perfume|BEHAVIORAL: Cue-induced inhalants craving
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biobehavioral Intervention to Enhance Hematopoietic Stem Cell Transplant Recovery
Status: COMPLETED
Conditions: Hodgkin Lymphoma|Non-Hodgkin Lymphoma|Plasma Cell Myeloma|Lymphoid Leukemia|Myeloid Leukemia|Myelodysplastic Syndromes|Multiple Myeloma
Interventions: BEHAVIORAL: Behavioral techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparison of Risperidone and Aripiprazole for Treatment of Patirnts With Methamphetamine-Associated Psychosis
Status: TERMINATED
Conditions: Methamphetamine Dependence
Interventions: DRUG: Risperidone|DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of GEMOX(Gemcitabine/Oxaliplatin) Versus XELOX(Xeloda/Oxaliplatin) in Advanced Biliary Tract Carcinoma
Status: UNKNOWN
Conditions: Biliary Tract (Intrahepatic, Extrahepatic Cholangiocarcinoma, Gall Bladder) Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GTI-2040, Oxaliplatin, and Capecitabine in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer or Other Solid Tumors
Status: COMPLETED
Conditions: Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IIIC Colon Cancer|Stage IIIC Rectal Cancer|Stage IVA Colon Cancer|Stage IVA Rectal Cancer|Stage IVB Colon Cancer|Stage IVB Rectal Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: GTI-2040|DRUG: oxaliplatin|DRUG: capecitabine|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Extract of Trigonella Foenum-graceum as Topical Phytoestrogen in Skin Aging Treatment of Post Menopausal Women
Status: COMPLETED
Conditions: Skin Aging
Interventions: DRUG: Trigonella foenum-graceum extract topical cream|OTHER: Facial Wash|OTHER: Sunscreen Cream|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow Stromal Cells for Inflammatory Bowel Diseases
Status: TERMINATED
Conditions: Inflammatory Bowel Disease
Interventions: OTHER: Bone Marrow Stromal Cell (BMSC) Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant PD-1 Inhibitor Combined With Cetuximab and Platinum in Resectable Locally Advanced Hypopharyngeal Carcinoma
Status: RECRUITING
Conditions: Locally Advanced Hypopharyngeal Carcinoma
Interventions: DRUG: three cycles (toripalimab + cetuximab + platinum)|PROCEDURE: Radical surgery|RADIATION: Radiotherapy or chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Ultrasound Cavitation Focused on Located Adiposity
Status: COMPLETED
Conditions: Subcutaneous Fat
Interventions: DEVICE: LIPOFOCUS|DEVICE: LIPOFOCUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Change in the Phase III Slope of the Volumetric Capnography by Prone Positioning in Acute Respiratory Distress Syndrome
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome|Ventilation Perfusion Mismatch|Respiratory Failure
Interventions: PROCEDURE: Prone Positioning
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Pregabalin and Placebo in Patients With Persistent Globus Sensation
Status: UNKNOWN
Conditions: Globus Sensation
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Advancing STOP: Self-regulation Therapy for Opioid Addiction and Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid-use Disorder|Chronic Pain
Interventions: OTHER: STOP Therapy Treatment group|OTHER: Treatment as usual (TAU) group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Novel CT-On-Rails or Trilogy Stereotactic Spine Radiotherapy System (SSRS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Neoplasms
Interventions: RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 1% Alendronate Gel in Treatment of Chronic Periodontitis Among Smokers
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Alendronate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Itch Sensation Induced by Multiple Applications of Pruritogens (Temporal Summation)
Status: NOT_YET_RECRUITING
Conditions: Histamine|Cowhage
Interventions: OTHER: Histamine|OTHER: Cowhage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Brief Mindfulness for Foot and Ankle Pain
Status: RECRUITING
Conditions: Pain
Interventions: BEHAVIORAL: Pain Coping Information|BEHAVIORAL: Mindfulness Practice (alone)|BEHAVIORAL: Mindfulness Introduction + Mindfulness Practice|BEHAVIORAL: Pain Introduction + Mindfulness Introduction + Mindfulness Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Appropriated Bowel Preparation Before Exploratory Laparotomy in Gynecologic Surgery
Status: COMPLETED
Conditions: Cathartic Colon|Other Surgical Procedures
Interventions: PROCEDURE: Soap suds enema (S.S.E.)|PROCEDURE: sodium chloride enema|PROCEDURE: No enema
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Telemedicine Consultation in Trauma and Orthopedic
Status: COMPLETED
Conditions: Trauma|Congenital Bone and Joint Abnormalities|Joint Diseases|Orthopedic Surgery Complications
Interventions: PROCEDURE: Telemedicine consultation|PROCEDURE: Treatment plan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Long-term Safety, Efficacy Tolerability of BYM338 in Patients With Sporadic Inclusion Body Myositis
Status: COMPLETED
Conditions: Sporadic Inclusion Body Myositis (sIBM)
Interventions: DRUG: BYM338 (Bimagrumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for the Application of Tirobot System
Status: COMPLETED
Conditions: Fusion of Spine (Disease)|Robotic Surgical Procedures
Interventions: PROCEDURE: robot-assisted spine surgery|PROCEDURE: free-hand surgery|DEVICE: TiRobot system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurofeedback in Clinical High Risk
Status: NOT_YET_RECRUITING
Conditions: Real Neurofeedback From DMN|Sham Neurofeedback From Motor Cortex
Interventions: OTHER: fMRI based neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Robot Based Tympanic Tube Placement
Status: WITHDRAWN
Conditions: Patient Operated on From a Vestibular Schwannoma With a Middle Ear Exclusion
Interventions: DEVICE: Robot Based Transtympanic drain placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effect of Cognitive Stimulating Interventions on Cognitive Self-Efficacy and Sense of Happiness Among Older Adults
Status: COMPLETED
Conditions: Self- Efficacy
Interventions: BEHAVIORAL: Cognitive Stimulating Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CVD 909 Vi Prime Boost Study
Status: COMPLETED
Conditions: Typhoid Fever
Interventions: BIOLOGICAL: CVD 909|DRUG: Placebo|BIOLOGICAL: Vi Polysaccharide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Moses Vaporization: Is Use of Moses 2.0 in Holmium Laser Ablation of the Prostate More Efficient
Status: NOT_YET_RECRUITING
Conditions: Benign Prostatic Hyperplasia|Lower Urinary Tract Symptoms
Interventions: PROCEDURE: Surgical Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison Study in Pancreatic Fiducial Placement
Status: WITHDRAWN
Conditions: Pancreatic Neoplasms
Interventions: DEVICE: 19 Gauge EUS FNA BNX|DEVICE: 22 Gauge EUS FNA BNX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-64565111 After Single Subcutaneous Administration at Different Injection Sites in Otherwise Healthy Overweight/Obese Adult Participants and a Study of JNJ-6456511 in Otherwise Healthy Obese Adult Participants After Multiple Dose
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: JNJ-64565111
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Double-Blind 2-Site Randomized Clinical Trial of Neurofeedback for ADHD
Status: COMPLETED
Conditions: Attention-Deficit/Hyperactivity Disorder
Interventions: DEVICE: Neurofeedback treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Bioavailability Study of LY2452473 and Tadalafil
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: LY2452473|DRUG: Tadalafil|DRUG: LY900010
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer
Status: WITHDRAWN
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Ascorbic Acid|DRUG: nab paclitaxel|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Bony Changes Around Dental Implant in Free Fibular Graft Versus Non-Vascularized Iliac Crest Graft"
Status: COMPLETED
Conditions: Crestal Bone Loss|Survival Rate
Interventions: PROCEDURE: placement of dental implants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Rituximab With Peripheral Stem Cell Transplantation in Treating Patients With Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: carmustine|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: leucovorin calcium|DRUG: methotrexate|DRUG: prednisone|DRUG: vincristine sulfate|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterizing Spondyloarthritis With 68Ga-FAPI PET/CT
Status: RECRUITING
Conditions: Spondyloarthritis|Axial Spondyloarthritis|Ankylosing Spondylitis
Interventions: DIAGNOSTIC_TEST: Drug: 68Ga-FAPI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety Study of IHL-305 (Irinotecan Liposome Injection) to Treat Advanced Solid Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: IHL-305 (irinotecan liposome injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of VOICES Elder Abuse Intervention in Primary Care Setting (VOICES-PC Feasibility)
Status: COMPLETED
Conditions: Elder Abuse
Interventions: BEHAVIORAL: Virtual cOaching in making Informed Choices on Elder Mistreatment Self-Disclosure (VOICES)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mobile-Application Based Respiratory Rehabilitation For COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Health-Related Quality Of Life|Dyspnea
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison and Clinical Utility of the Portable Pressure Measuring Device for Garment Pressure Measurement on Hypertrophic Scar by Burn Injury During Compression Therapy
Status: UNKNOWN
Conditions: Burns|Hypertrophic Scar
Interventions: PROCEDURE: pressure monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fish Oil and Green Tea Extract in Preventing Prostate Cancer in Patients Who Are at Risk for Developing Prostate Cancer
Status: COMPLETED
Conditions: Precancerous Condition|Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: green tea catechin extract|DIETARY_SUPPLEMENT: fish oil|OTHER: placebo|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Selumetinib and Akt Inhibitor MK2206 or mFOLFOX Therapy Comprising Oxaliplatin and Fluorouracil in Treating Patients With Metastatic Pancreatic Cancer Previously Treated With Chemotherapy
Status: COMPLETED
Conditions: Pancreatic Acinar Cell Carcinoma|Pancreatic Ductal Adenocarcinoma|Recurrent Pancreatic Carcinoma|Stage IV Pancreatic Cancer
Interventions: DRUG: Akt Inhibitor MK2206|DRUG: Fluorouracil|DRUG: Oxaliplatin|DRUG: Selumetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Randomized Trial Assessing the Utility of a Test Dose Program With Taxanes
Status: COMPLETED
Conditions: Supportive|Ill-defined Sites
Interventions: DRUG: paclitaxel, docetaxel, taxane|DRUG: taxane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Left Atrial Appendage Closure as Secondary Prevention of Atrial Fibrillation-related Embolic Events
Status: RECRUITING
Conditions: Non-valvular Atrial Fibrillation|Embolic Stroke
Interventions: DIAGNOSTIC_TEST: Transthoracic Echocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NEO6860, a TRPV1 Antagonist, First in Human Study
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: NEO6860|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single-Session Intervention Targeting Self-Injurious Behavior in Adolescents
Status: UNKNOWN
Conditions: Nonsuicidal Self Injury|Self Hatred|Suicidal Thoughts|Suicide Attempts
Interventions: OTHER: Project SAVE ("Stop Adolescent Violence Everywhere") SSI|OTHER: Active Comparator: Supportive Therapy ("Share Your Feelings") SSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and Carboplatin in Treating Women Who Are Undergoing Surgery for Newly Diagnosed, Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stockholm hyperTRIglyceridemia REGister (STRIREG) Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Familial Hypertriglyceridemia
Interventions: OTHER: Heredity for cardiovascular disease|OTHER: Heredity for pancreatitis|OTHER: Heredity for type 2 diabetes|OTHER: Heredity for hypertriglyceridemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of a Clostridium Difficile Toxoid Vaccine (ACAM-CDIFF™) in Subjects With Clostridium Difficile Infection
Status: COMPLETED
Conditions: Diarrhea|Clostridium Difficile Infection
Interventions: BIOLOGICAL: 0.9% Normal Saline|BIOLOGICAL: Clostridium difficile toxoid vaccine|BIOLOGICAL: Clostridium difficile toxoid vaccine with adjuvant|BIOLOGICAL: Clostridium difficile toxoid vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety of GSK2398852 When Co-administered With GSK2315698 in Patients With Systemic Amyloidosis
Status: COMPLETED
Conditions: Amyloidosis
Interventions: DRUG: GSK2398852|DRUG: GSK2315698
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intraoperative Virtual Reality on Anxiety and Vital Findings in Patients Total Knee Replacement Surgery
Status: COMPLETED
Conditions: Total Knee Replacement Surgery|Virtual Reality
Interventions: BEHAVIORAL: Virtual reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Milk Matters in Malnutrition, is it the Lactose or Dairy Protein?
Status: COMPLETED
Conditions: Malnutrition, Child
Interventions: DIETARY_SUPPLEMENT: RUSF skimmed milk powder|DIETARY_SUPPLEMENT: RUSF milk protein concentrate and sucrose|DIETARY_SUPPLEMENT: RUSF soy protein and whey permeate|DIETARY_SUPPLEMENT: RUSF soy and sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of MM-093 to Treat Patients With Uveitis
Status: COMPLETED
Conditions: Uveitis
Interventions: DRUG: MM-093|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Effects of Intensive Lipid Lowering Treatment With Ezetimibe/ Simvastatin (Vytorin®) Assessed by Virtual Histology-Intravascular Ultrasound (VH-IVUS) and Optical Coherence Tomography (OCT) on Plaque Characteristics in Patients With Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DEVICE: Zotalolimus Eluting Stent|DEVICE: Everolimus eluting stent|DRUG: Ezetimibe 10mg & Simvastatin 40mg|DRUG: Pravastatin 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spironolactone and Prevention of Calcineurin Inhibitor Toxicity in Kidney Transplant Recipients
Status: SUSPENDED
Conditions: Kidney Transplant
Interventions: DRUG: spironolactone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Unguided Sacroiliac Injection: Effect on Refractory Buttock Pain in Patients With Spondyloarthropathies
Status: UNKNOWN
Conditions: Spondylarthropathy
Interventions: PROCEDURE: guide-free sacroiliac corticosteroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Acceptability of Internet-delivered Treatment for Depression, Anxiety and Stress
Status: COMPLETED
Conditions: Depression|Anxiety|Stress
Interventions: OTHER: Space from Depression|OTHER: Space from Anxiety|OTHER: Space from Stress
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Effects of Disulfiram in Patients With Moderate COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Disulfiram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II/III of Recombinant Human Albumin Injection
Status: COMPLETED
Conditions: Hepatic Ascites
Interventions: BIOLOGICAL: Recombinant Human Albumin Injection|BIOLOGICAL: Human Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Assessment in Elderly MI Patients With Multivessel Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocardial Infarction
Interventions: OTHER: Culprit-only revascularization|OTHER: Complete functionally-guided revascularization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation for Health Improvement (TFM3)
Status: UNKNOWN
Conditions: Ulcerative Colitis|Irritable Bowel Syndrome|Crohn Disease|Irritable Bowel
Interventions: OTHER: Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Design of 'Influence of Sarpogrelate in Patients With Renal Impairment or Diabetes Mellitus' Study
Status: COMPLETED
Conditions: Coronary Artery Disease|Diabetes Mellitus|Renal Insufficiency, Chronic
Interventions: DRUG: Sarpogrelate|DRUG: Aspirin|DRUG: Clopidogrel|DRUG: Placebo (for Sarpogrelate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Carboplatin/Paclitaxel and Carboplatin/Paclitaxel/Bevacizumab With and Without Pictilisib in Previously Untreated Advanced or Recurrent Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: pictilisib|DRUG: Placebo|DRUG: bevacizumab|DRUG: carboplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacoepidemiology Treatment of Symptomatic Pulmonary Embolism in Hospitalized Patients Aged 75 Years or More: PEAGE
Status: COMPLETED
Conditions: Elderly|Pulmonary Embolism|Anticoagulants
Interventions: OTHER: 4 blood samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating the Safety and Efficacy of Bapineuzumab in Alzheimer Disease Patients
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DRUG: bapineuzumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sciatic Nerve Block for Ankle/Foot Surgeries. A Comparison Between a Premixed Solution of Lidocaine Plus Bupivacaine and Consecutive Infiltration of Lidocaine and Bupivacaine
Status: COMPLETED
Conditions: Open Reduction Internal Fixation(ORIF) of Lateral Malleolus
Interventions: DRUG: 2% lidocaine/adrenaline and 0.5% bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Ursodeoxycholic Acid to Treat Chronic Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Ursodeoxycholic acid 150mg / day|DRUG: Ursodeoxycholic acid 600mg / day|DRUG: Ursodeoxycholic acid 900mg / day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Positive End-expiratory Pressure-induced Increase in Central Venous Pressure as a Predictor of Fluid Responsiveness in Robot-assisted Laparoscopic Surgery
Status: COMPLETED
Conditions: Prostatic Neoplasm|Urinary Bladder Neoplasm
Interventions: PROCEDURE: Fluid loading of volulyte 300 ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating the Effects of Traditional Chinese Medicine by N-of-1 Trials
Status: UNKNOWN
Conditions: Bronchiectasis|Quality of Life|Traditional Chinese Medicine|Sputum|Symptoms|Individuality
Interventions: DRUG: Individualized Decoction|DRUG: placebo|DRUG: Tested drug minus heat-clearing herbs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study to Evaluate the Efficacy and Safety of AGSAVI in Patients With Essential Hypertension
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: AGSAVI|DRUG: AGLS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Investigation of a Supplement to Enhance Sleep Quality and Quantity
Status: COMPLETED
Conditions: Sleep|Sleep Disturbance|Sleep Hygiene
Interventions: DIETARY_SUPPLEMENT: Beam Organics Dream Powder|DIETARY_SUPPLEMENT: Beam Organics Dream Powder Extra Strength|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Capsule Versus Conventional Colonoscopy in Patient Following Colorectal Surgery
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DEVICE: PillCam Colon 2|PROCEDURE: Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Breast Cancer|Ovarian Cancer|Non Small Cell Lung Cancer|Colorectal Cancer|Pancreatic Cancer|Renal Cell Carcinoma|Nasopharyngeal Cancer|Head and Neck Squamous Cell Carcinoma|Gastric Cancer
Interventions: BIOLOGICAL: P-MUC1C-ALLO1 CAR-T cells|DRUG: Rimiducid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inflammatory Stress Response in Pediatric Inguinal Hernia Repair
Status: COMPLETED
Conditions: Inguinal Hernia, Indirect|Children, Only|Inflammatory Response|Surgery|Interleukin-6|Tumor Necrosis Factor Alpha|C Reactive Protein|White Blood Cell Count, Leukocytes
Interventions: PROCEDURE: Operation - PIRS|PROCEDURE: Operation - MARCY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Enteric-coated Mycophenolate Sodium (EC-MPS) in de Novo Kidney Transplant Recipients
Status: COMPLETED
Conditions: De Novo Kidney Transplant Recipients
Interventions: DRUG: Enteric-coated Mycophenolate sodium (EC-MPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: BrUOG 302:BYL719, Capecitabine and Radiation for Rectal Cancer: A Brown University Oncology Research Group Study
Status: TERMINATED
Conditions: Rectal Cancer
Interventions: DRUG: BYL719|DRUG: Capecitabine|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Tolerability of MYK-224 in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiomyopathy, Hypertrophic
Interventions: DRUG: MYK-224
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Seek, Test, and Treat Intervention to Reduce Chlamydia Trachomatis Disparities
Status: NOT_YET_RECRUITING
Conditions: Chlamydia|Gonorrhea|Hiv|Syphilis
Interventions: OTHER: Chlamydia, gonorrhea, syphilis, and HIV screening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Comparison of Body Fat Distribution in HIV-1 Infected Patients Receiving, Since the Beginning and for at Least Two Years, an Antiretroviral Therapy Based on Efavirenz or Lopinavir/Ritonavir Combined With Tenofovir + Emtricitabine or Lamivudine
Status: COMPLETED
Conditions: HIV Infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Late Night Study 2: End-of-Day Assessment of Asymptomatic and Symptomatic Soft Lens Wearers
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: AquaComfort Plus|DEVICE: Acuvue Oasys 1-Day
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ruxolitinib in Neuromyelitis Optica Spectrum Disorders
Status: WITHDRAWN
Conditions: Neuromyelitis Optica Spectrum Disorder Relapse
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study With Fluticasone Furoate Nasal Spray And Vehicle Placebo For The Treatment Of Perennial (Year-round) Allergic Rhinitis
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: fluticasone furoate nasal spray|DRUG: vehicle placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Atrophic Acne Scars With a Fractional CO2 Laser at 1 Versus 3 Months Intervals
Status: UNKNOWN
Conditions: Atrophic Acne Scars
Interventions: PROCEDURE: Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of microRNA-210 in Regulating Oxidative Stress in Patients With PAD
Status: RECRUITING
Conditions: Peripheral Arterial Disease|Vascular Diseases, Peripheral|Arterial Occlusive Diseases|Atherosclerosis
Interventions: PROCEDURE: Revascularization operation|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE