pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Trail of Second-line Chemotherapy Sequential NKG2D CAR-NK Cell Therapy for Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer Non-resectable
Interventions: BIOLOGICAL: chemotherapy sequential CAR-NK cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Bupivacaine Effect On The Response To Awake Extubation During Emergence From General Anesthesia
Status: COMPLETED
Conditions: Thyroid Diseases
Interventions: DRUG: normal saline 0.9%|DRUG: Bupivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine Headache
Status: NOT_YET_RECRUITING
Conditions: Migraine
Interventions: DRUG: Rimegepant|DRUG: Rizatriptan Benzoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Conventional GlideScope to Single-Use GlideScope Cobalt for Orotracheal Intubation
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Conventional (reusable) Glidescope|DEVICE: Single-use Glidescope videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety and Efficacy of Atezolizumab in Previously-Treated Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intracameral Carbachol and Epinephrine on Choroidal Thickness
Status: COMPLETED
Conditions: Epinephrine Toxicity|Cataract|Carbachol Adverse Reaction|Choroid Disease
Interventions: PROCEDURE: Intracameral administration of epinephrine and carbachol during cataract surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of GC3110A in Healthy Infants From 6 Months to 35 Months of Age
Status: UNKNOWN
Conditions: Influenza Vaccine
Interventions: BIOLOGICAL: GC3110A|BIOLOGICAL: GCFLU Pre-filled syringe inj.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Changes in the Gut Microbiota of Patients Undergoing Allogeneic Stem Cell Transplantation (COLLECT)
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|Graft-versus-host-disease|Allogeneic Hematopoietic Stem Cell Transplantation|Stem Cell Transplant Complications
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Palliative Radiotherapy (RT) for Liver Metastases (Mets) and Hepatocellular Carcinoma (HCC)(COLD 4)
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Hepatic Metastasis
Interventions: RADIATION: Palliative RT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease
Status: NOT_YET_RECRUITING
Conditions: Arterial Disease of Legs
Interventions: DEVICE: MagicTouch PTA Sirolimus drug coated balloon|DEVICE: Placebo balloon angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BLI400-302: A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adults
Status: COMPLETED
Conditions: Constipation|Chronic Idiopathic Constipation|CIC
Interventions: DRUG: BLI400 Laxative|DRUG: BLI400 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compound Sodium Alginate Double Action Chewable Tablets 4-hour Esophageal pH Study in GERD Patients
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Sodium Alginate Double Action Tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification of Molecular Biomarkers for Cancer Target Therapy Efficacy
Status: UNKNOWN
Conditions: Cancer
Interventions: OTHER: RNA sequencing|OTHER: Transcriptome analysis|DRUG: target drug with the score above 0,1|DRUG: target drug with the score equal or below 0,1|DRUG: non-target drug|DRUG: palliative care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: WBV and Acute Lateral Ankle Sprain
Status: UNKNOWN
Conditions: Postural Control|Subjective Instablity
Interventions: DEVICE: Whole body vibration (Galileo® Med M Plus, Novotec, Pforzheim, Germany)|OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Study of Safety of H1337 in Healthy Volunteers
Status: NOT_YET_RECRUITING
Conditions: Glaucoma Open-Angle Primary|Ocular Hypertension
Interventions: DRUG: H-1337 1.0%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Will Evaluate The Safety And Efficacy Of Anidulafungin In Patients With Candidemia Or Invasive Candidiasis
Status: COMPLETED
Conditions: Candidiasis
Interventions: DRUG: Eraxis (anidulafungin)|DRUG: Diflucan (fluconazole)|DRUG: Vfend (voriconazole)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and PK-PD Study of Oral L-CIT in Preterm Infants With BPD±PH and NEC
Status: RECRUITING
Conditions: BPD - Bronchopulmonary Dysplasia|Pulmonary Hypertension|NEC
Interventions: DIETARY_SUPPLEMENT: L-Citrulline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lidocaine and Esmolol to Improve the Quality of Recovery
Status: TERMINATED
Conditions: Pain|Constipation|Nausea|Vomiting
Interventions: DRUG: Lidocaine|DRUG: Esmolol|DRUG: Lidocaine + Esmolol (Combo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Optic Nerve Diameter on Postoperative Cognitive Function in Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Intracranial Pressure Increase|Postoperative Cognitive Dysfunction
Interventions: DIAGNOSTIC_TEST: measuring optic nerve diameter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dietary Intake of Whole Walnuts in Adult Subjects Under Low Cardiovascular Risk
Status: COMPLETED
Conditions: Cardiovascular Risk Factor|Metabolic Syndrome|Hypertension
Interventions: DIETARY_SUPPLEMENT: Whole Walnuts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Knee Biofeedback Rehabilitation Through Game Therapy
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DEVICE: KneeBRIGHT System|OTHER: Control Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cryoanalgesia to Prevent Acute and Chronic Pain Following Nuss Procedure
Status: COMPLETED
Conditions: Funnel Chest|Excavatum, Pectus
Interventions: DEVICE: intercostal nerves cryoanalgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy in Patients With Moderate Risk Mid Rectal Cancer
Status: ENROLLING_BY_INVITATION
Conditions: Rectal Neoplasms Malignant|Rectum Carcinoma|Rectal Cancer
Interventions: DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Capecitabine|RADIATION: Radiotherapy|PROCEDURE: Rectal cancer surgery|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of New Elastomer for Maxillofacial Prosthetics
Status: COMPLETED
Conditions: Facial Neoplasms|Head and Neck Neoplasms|Head Injuries, Penetrating|Birth Injuries
Interventions: COMBINATION_PRODUCT: Chlorinated polyethylene elastomer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Transcranial Magnetic Stimulation for "Voices"
Status: COMPLETED
Conditions: Schizophrenia|Hallucinations
Interventions: DEVICE: 1-hertz Repetitive Transcranial Magnetic Stimulation|DEVICE: Active 1-Hertz Repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Adding Braun Anastomosis to Standard Child Reconstruction After Pancreatoduodenectomy
Status: RECRUITING
Conditions: Pancreatic Disease|Pancreatic Cancer|Delayed Gastric Emptying
Interventions: PROCEDURE: Braun anastomosis|PROCEDURE: Standard Child reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Transdiagnostic Internet Intervention for Parents of Children With Anxiety and Depressive Symptoms
Status: COMPLETED
Conditions: Emotional Problem|Anxiety|Depression|Psychological Distress
Interventions: BEHAVIORAL: ParentKIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Melatonin on Seizure Outcome, Neuronal Damage and Quality of Life in Patients With Generalized Epilepsy
Status: COMPLETED
Conditions: Generalized Epilepsy
Interventions: DRUG: Melatonin 3 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: "Efficacy Of 1.2% Rosuvastatin Gel In The Management Of Infrabony Defects"
Status: COMPLETED
Conditions: Adult Periodontitis
Interventions: DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Effectiveness and Operability of Using the New Tissue Containment System During Laparoscopic Ovarian Cystectomy
Status: RECRUITING
Conditions: Ovary Neoplasm|Surgery
Interventions: DEVICE: the New Tissue Containment System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Local Subfascial and Intramuscular Tranexamic Acid Administration in Pediatric Patient Undergoing Scoliosis Surgery, Double Blind Randomized Control Trial
Status: UNKNOWN
Conditions: Blood Loss, Surgical|Scoliosis
Interventions: DRUG: Tranexamic acid injection|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Increasing Caregiver Engagement in Juvenile Drug Courts
Status: COMPLETED
Conditions: Substance Abuse
Interventions: BEHAVIORAL: Caregiver Contingency Management + Usual Drug Court Treatment|BEHAVIORAL: Usual Drug Court Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Online MBSR Program for Cancer Survivors With Chronic Neuropathic Pain
Status: COMPLETED
Conditions: Cancer|Painful Neuropathy|Chronic Pain|Worries; Pain or Disability
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction (MBSR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Panobinostat in Combination With Sorafenib in Kidney, Soft Tissue or Lung Cancers
Status: COMPLETED
Conditions: Renal Cancer|Non Small Cell Lung Cancer (NSCLC)|Soft Tissue Sarcoma
Interventions: DRUG: Panobinostat (LBH589), Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Kidney Injury in Children Operated for Congenital Heart Disease
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: PROCEDURE: Remote ischemic preconditioning (RIPC)|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Level of Expression of CD45RC on T Lymphocytes as a Predictive Biomarker of Acute Rejection After Renal Transplantation
Status: RECRUITING
Conditions: End-stage Renal Disease
Interventions: OTHER: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Observational Study of Misuse of High Dose Buprenorphine (Subutex® or Generic) in Opiate-Addicted Patients in France (Study P05186AM1)(COMPLETED)
Status: COMPLETED
Conditions: Buprenorphine|Naloxone|Opiate-related Disorders|Opiate Dependence|Drug Abuse
Interventions: DRUG: buprenorphine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination of Immune Checkpoint in Locally Advanced or Metastatic MSI/dMMR Esogastric Adenocarcinomas
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer|MSI-H|Metastatic Cancer|Advanced Cancer
Interventions: DRUG: Balstilimab|DRUG: Botensilimab|DRUG: Folfox Protocol|DRUG: XELOX|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Discovering the Effect of Venous Insufficiency on Nocturia (DEVINe)
Status: COMPLETED
Conditions: Edema Leg|Venous Insufficiency of Leg|Nocturia|Bio-Impedance Measurements
Interventions: BEHAVIORAL: Tilt Test|DEVICE: Inbody S10|DEVICE: Tape measurements|DEVICE: SOMNOtouchTMNIBP, Vivisol, Belgium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nonconvulsive Electrotherapy: a Proof-of-concept Trial
Status: COMPLETED
Conditions: Depressive Disorder|Bipolar Disorder|Schizoaffective Disorder
Interventions: DEVICE: Nonconvulsive electrotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Assess The Efficacy And Safety Of Voriconazole In Chinese Patients With Serious Deep Tissue Fungal Infections
Status: COMPLETED
Conditions: Invasive Fungal Infections
Interventions: DRUG: voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Daylight on Patients With Acute Myocardial Infarction
Status: TERMINATED
Conditions: Coronary Arteriosclerosis|Myocardial Infarction
Interventions: OTHER: Day Light|OTHER: Room Light
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Probiotics on the Gut Microbiome and Immune System in Operable Stage I-III Breast or Lung Cancer
Status: COMPLETED
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Breast Adenocarcinoma|Stage I Lung Cancer AJCC v8|Stage II Lung Cancer AJCC v8|Stage III Lung Cancer AJCC v8
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Probiotic|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Quadruple and Phytomedicine-based Therapies in H. Pylori Infection
Status: COMPLETED
Conditions: Helicobacter Pylori [H. Pylori] as the Cause of Diseases
Interventions: DRUG: Quadruple Allopathic therapy|DRUG: Pylorex plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of Travoprost/Timolol Combination in Patients With Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Travoprost 0.004%/Timolol 0.5% BAC-free ophthalmic solution|DRUG: Travoprost 0.004%/Timolol 0.5% ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Resveratrol and Vitamin C on Insulin Resistance Among Postmenopausal Women
Status: UNKNOWN
Conditions: Postmenopausal|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: vitamin C (500 mg / day) + placebo|DIETARY_SUPPLEMENT: resveratrol (500 mg / day) + placebo|DIETARY_SUPPLEMENT: vitamin C (500 mg / day) and resveratrol (500 mg / day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective, Single Arm, Single Center Study of Duvelisib Combined With Chidamide in the Treatment of Newly Diagnosed Peripheral T-cell Lymphoma (PTCL)
Status: RECRUITING
Conditions: Newly Diagnosed Peripheral T-cell Lymphoma
Interventions: DRUG: Duvelisib, Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Application Support for Women With Breast Cancer Undergoing Chemotherapy
Status: RECRUITING
Conditions: Breast Neoplasms
Interventions: DEVICE: Mobile device as a support tool for the treatment of women with breast cancer undergoing chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Two Methods of Patellar Resurfacing in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: PROCEDURE: Patellar resurfacing with freehand technique|PROCEDURE: Patellar resurfacing with resection guide technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Teysuno (S-1) Combined With Epirubicin and Oxaliplatin in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Patients With Advanced or Metastatic Solid Tumors
Interventions: DRUG: Teysuno (S1) in combination with epirubicin and oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A-RGEMOX in the Treatment of Early Relapsed/Refractory DLBCL
Status: RECRUITING
Conditions: Diffuse Large B-cell Lymphoma Recurrent|Diffuse Large B Cell Lymphoma Refractory
Interventions: DRUG: Anlotinib hydrochloride, Rituximab, gemcitabine, oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid Tumors
Status: RECRUITING
Conditions: Neoplasms|Non-small-cell Lung Cancer|Melanoma|Squamous Cell Carcinoma of the Head and Neck|Renal Cell Carcinoma|Urothelial Carcinoma|Colorectal Carcinoma|Ovarian Carcinoma
Interventions: DRUG: PF-07820435|BIOLOGICAL: Sasanlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Evaluation of a Psychological Intervention in Videogame Format for the Promotion of Active Aging
Status: RECRUITING
Conditions: Aging|Aging Problems
Interventions: BEHAVIORAL: Video game based intervention|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of SFPP in Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis Knee Pain
Interventions: DRUG: Esflurbiprofen|DRUG: Diclofenac diethylamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addiction in Intensive Cardiac Care Units
Status: ACTIVE_NOT_RECRUITING
Conditions: Intensive Care Unit Syndrome|Drug Abuse|Substance-Related Disorders|Cardiovascular Events|Cardiac Disease
Interventions: OTHER: urine test|OTHER: Fagerström questionnaire|OTHER: Exhaled carbon monoxide (CO) measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Isopropyl Alcohol Against Chlorhexidine - Isopropyl Alcohol as Antiseptics to Prevent Hemoculture's Contamination
Status: COMPLETED
Conditions: Infectious Diseases
Interventions: BIOLOGICAL: chlorhexidine in isopropyl alcohol|BIOLOGICAL: Isopropyl alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hemostasis Alterations in Neurosurgical Patients
Status: UNKNOWN
Conditions: Glioma|Coagulopathy|Acquired Platelet Function Disorder|Thromboelastometry|Surgery
Interventions: PROCEDURE: Exposure to glioma resection surgery|PROCEDURE: Exposure to colon resection surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Predictors of Acute Exacerbation in Patients With COPD - an Observational Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease|COPD|COPD Exacerbation|COPD Exacerbation Acute
Interventions: OTHER: Prospective monitoring of a large variety of parameters
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study of YQ1 Plus Cisplatin-based Chemotherapy in Advanced NSCLC EGFR Wild Type
Status: UNKNOWN
Conditions: Epithelial Growth Factor Receptor Negative Non-small Cell Lung Cancer
Interventions: DRUG: YQ1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Biphasic Insulin Aspart 30 in Combination With Metformin in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart|DRUG: insulin glargine|DRUG: metformin|DRUG: glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fexofenadine Use in Gastroesophageal Reflux Symptoms
Status: TERMINATED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: Fexofenadine|DRUG: Placebo - Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Steady-State Feedback Actions of Testosterone on Luteinizing Hormone Secretion in Young and Older Men
Status: COMPLETED
Conditions: Hypogonadism
Interventions: DRUG: Ketoconazole, Dexamethesone, Androgel,GnRH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose:
Clinical trial: Randomized Trial to Evaluate Suppressive Effect of High-Dose Acyclovir Versus Once-Daily Valacyclovir on Persons With HSV-2
Status: COMPLETED
Conditions: Genital Herpes
Interventions: DRUG: acyclovir|DRUG: valacyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myloablative Cord Blood Transplant in Haematological Malignancies (MAC UCBT)
Status: TERMINATED
Conditions: Leukaemia|Lymphoma|Other Haematological Diseases
Interventions: OTHER: Umbilical Cord Blood Transplant|DRUG: Cyclophosphamide|RADIATION: Total body irradiation|DRUG: Busulfan|DRUG: Melphalan|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Combined Double-Bundle ACL Reconstruction With Lateral Retinacular Release to Prevent Patellofemoral Malalignment in Isolated ACL Rupture
Status: COMPLETED
Conditions: ACL Injury
Interventions: PROCEDURE: ACL reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Pharmacodynamic Study of Lenograstim for Hematopoietic Stem Cell Mobilization
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: lenograstim 10 microgram/kg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Modified Otago and Neuromuscular Exercise on Falling and Physical Function in Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Modified Otago Exercise|PROCEDURE: Neuromuscular Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Ceftolozane/Tazobactam (MK-7625A) in Combination With Metronidazole in Japanese Participants With Complicated Intra-abdominal Infection (MK-7625A-013)
Status: COMPLETED
Conditions: Intra-abdominal Infection|Complicated Intra-abdominal Infection
Interventions: DRUG: MK-7625A 1.5 g (ceftolozane 1 g/tazobactam 0.5 g)|DRUG: metronidazole 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PReservation Study of Ovarian Function And Hemostasis, and Its Safety of Surgiguard@ During Laparoscopic Ovarian Cystectomy
Status: COMPLETED
Conditions: Ovarian Cyst Benign
Interventions: DRUG: Surgiguard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PrizValve® Transcatheter Aortic Valve Replacement Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: PrizValve® valve and transapical delivery system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrophysiological Optimization of Left Ventricular Lead Placement in CRT
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DEVICE: Cardiac Resynchronization Therapy (St. Jude Qaudripolar LV lead)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MLN9708 and Dexamethasone for High-Risk Smoldering Multiple Myeloma
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: MLN9708|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy and Docetaxel With Either Fluorouracil or Cisplatin as First-Line Therapy in Treating Patients With Metastatic Pancreatic Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: cisplatin|DRUG: docetaxel|DRUG: fluorouracil|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics in PBC Patients of Poor Response to UDCA
Status: UNKNOWN
Conditions: Primary Biliary Cholangitis (PBC)
Interventions: DRUG: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lansoprazole Versus Mosapride for Functional Dyspepsia
Status: COMPLETED
Conditions: Functional Dyspepsia|Epigastric Pain Syndrome|Post Prandial Distress Syndrome
Interventions: DRUG: lansoprazole|DRUG: mosapride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Pemetrexed Combined With High-dose Furmonertinib and Beva for EGFR-m NSCLC With Leptomeningeal Metastases
Status: NOT_YET_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Intrathecal Pemetrexed and high-dose Furmonertinib plus bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Green Tea (Epigallocatechin Gallate) on Albuminuria in Patients With Diabetic Nephropathy.
Status: COMPLETED
Conditions: Diabetic Nephropathy|Hypertension
Interventions: DRUG: Green tea extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Tralokinumab in Subjects With Moderate to Severe Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: Tralokinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of GNX102 in Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Solid Tumor|Metastatic Cancer|Advanced Cancer|Unresectable Solid Neoplasm
Interventions: DRUG: GNX102|DRUG: GNX102
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Pilates and Taping in Office Workers With Neck Pain
Status: RECRUITING
Conditions: Neck Pain
Interventions: OTHER: Pilates|OTHER: Pilates and Kinesiotape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment With Omalizumab to Improve the Asthmatic Response to Rhinovirus Experimental Infection With Rhinovirus
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: omalizumab|BIOLOGICAL: Rhinovirus (strain 16)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Electronic Patient-reported Outcomes (e-PROs) in Early Intervention
Status: COMPLETED
Conditions: Developmental Disability|Development Delay
Interventions: BEHAVIORAL: Young Children's Participation and Environment Measure (YC-PEM) electronic patient-reported outcome (e-PRO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Kinesiology Taping Technique in Post-mastectomy Breast Cancer Related Lymphedema
Status: COMPLETED
Conditions: Post Mastectomy Lymphedema
Interventions: OTHER: Kinesiology taping technique with exercise therapy|OTHER: Compression decongestive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of MBI 226 1.25% and 2.5% Topical Acne Solutions in the Treatment of Acne
Status: COMPLETED
Conditions: Acne Vulgaris|Acne|Propionibacterium Acnes
Interventions: DRUG: MBI 226 Acne Solutions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Band Versus Ring for Tricuspid Regurgitation
Status: UNKNOWN
Conditions: Tricuspid Regurgitation
Interventions: PROCEDURE: Tricuspid Annuloplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Barbed Suture Fascia Closure on Incisional Hernia in Midline Laparotomy for Gynecological Diseases (BARBHER)
Status: UNKNOWN
Conditions: Gynecologic Disease
Interventions: DEVICE: Barbed PDS suture (STRATAFIX Symmetric PDS Plus)|DEVICE: Non-barbed PDS suture (PDS Plus)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Propolis Administration for Dysmenorrhea in Endometriosis Patient With Levonorgestrel Implant Therapy
Status: RECRUITING
Conditions: Endometriosis|Dysmenorrhea
Interventions: DIETARY_SUPPLEMENT: Propolis|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility of Using a Mobile Device Controlled Micro-pressure Pulse Insufflator for Acute Migraine Relief
Status: TERMINATED
Conditions: Migraine
Interventions: DEVICE: insufflation|DEVICE: placebo insufflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial
Status: RECRUITING
Conditions: Metastatic Clear Cell Renal Cell Carcinoma|Metastatic Renal Cell Carcinoma|Stage IV Renal Cell Cancer AJCC v8
Interventions: PROCEDURE: Cytoreductive Nephrectomy|DRUG: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Tolerability and Safety of Adding Ustekinumab to INGAP Peptide for 12 Weeks in Adult Patients With TD1 Melitis
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: INGAP Peptide, Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Micro-Dose, Macro-Impact: Leveraging Psychedelics in Frontline Healthcare Workers During the COVID-19 Pandemic
Status: UNKNOWN
Conditions: Acute Stress Disorder
Interventions: DRUG: Sublingual Micro-Dose Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Efficacy of Rituximab in Combination With Glucocorticoids in Participants With Wegener's Granulomatosis or Microscopic Polyangitis
Status: COMPLETED
Conditions: Wegener's Granulomatosis or Microscopic Polyangiitis
Interventions: DRUG: Methylprednisolone|DRUG: Prednisone|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase-II Study of Lu177DOTATOC in Adults With STTR(+)Pulmonary, Pheochromocytoma, Paraganglioma, Unknown Primary, Thymus NETs (PUTNET), or Any Other Non-.GEP-NET.
Status: WITHDRAWN
Conditions: Pulmonary Neuroendocrine Neoplasm|Pheochromocytoma|Paraganglioma|Thymus Carcinoid|Unknown Primary Tumors|Neuroendocrine Tumors|Neuroendocrine Skin Carcinoma|Neuroendocrine Breast Tumor|Neuroendocrine Carcinoma Metastatic|Neuroendocrine Neoplasm of Ovary
Interventions: DRUG: 177Lu-DOTATOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Nurse-Led Intervention for Fear of Progression in Advanced Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lung Carcinoma|Metastatic Malignant Female Reproductive System Neoplasm|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: OTHER: Educational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Human Penile Allotransplantation
Status: RECRUITING
Conditions: Amputation|Wounds and Injuries|Amputation, Traumatic|Urologic Surgical Procedures, Male|Amputation, Traumatic/Surgery|Penis/Transplantation|Penis/Surgery|Penis/Injuries|Congenital Anomaly, Male Genitalia
Interventions: BIOLOGICAL: Monoclonal Antibody (Humanized Anti-CD52)|DRUG: Tacrolimus|PROCEDURE: Penile Allotransplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Trial of Lorenzo's Oil in Adrenomyeloneuropathy
Status: TERMINATED
Conditions: Adrenomyeloneuropathy|Adrenoleukodystrophy
Interventions: DRUG: Lorenzo's oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Study Comparing Iberdomide, Daratumumab and Dexamethasone (IberDd) Versus Daratumumab, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Dexamethasone|DRUG: Daratumumab|DRUG: Bortezomib|DRUG: Iberdomide|DRUG: Iberdomide|DRUG: Iberdomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnified Intelligence Chromoendoscopy Plus Probe-based Confocal Laser Endomicroscopy for Gastric Intestinal Metaplasia Diagnosis
Status: COMPLETED
Conditions: Gastric Intestinal Metaplasia
Interventions: DEVICE: Confocol laser endomicroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study on the Effect of Intravenous Ascorbic Acid on Intraoperative Blood Loss in Women With Uterine Myoma
Status: COMPLETED
Conditions: Uterine Leiomyoma
Interventions: DRUG: ascorbic acid|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare Apixaban and Vitamin-K Antagonists in Patients With Atrial Fibrillation (AF) and End-Stage Kidney Disease (ESKD)
Status: COMPLETED
Conditions: Atrial Fibrillation|End-stage Kidney Disease
Interventions: DRUG: Apixaban|DRUG: Phenprocoumon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endocrine Therapy With or Without Abemaciclib (LY2835219) Following Surgery in Participants With Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Abemaciclib|DRUG: Standard Adjuvant Endocrine Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 601 Versus Ranibizumab in Patients With Branch Retinal Vein Occlusion (BRVO)
Status: UNKNOWN
Conditions: Branch Retinal Vein Occlusion
Interventions: DRUG: 601 1.25mg|DRUG: Ranibizuman 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Efficacy, Safety and Tolerability Study of Zolbetuximab (Experimental Drug) Plus mFOLFOX6 Chemotherapy Compared to Placebo Plus mFOLFOX6 as Treatment for Gastric and Gastroesophageal Junction (GEJ) Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer|Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer|Metastatic Gastric Adenocarcinoma or Cancer|Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma
Interventions: DRUG: zolbetuximab|DRUG: placebo|DRUG: oxaliplatin|DRUG: folinic acid|DRUG: fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EBV-TCR-T（YT-E001）for Patients With EBV-positive Recurrent or Metastatic NPC
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: BIOLOGICAL: EBV-TCR-T (YT-E001) cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Study of the Impact on the Autonomy of the Elderly of 75 Years of Age and Older by the UPSAV
Status: COMPLETED
Conditions: the Elderly of 75 Years and Older Living at Home
Interventions: OTHER: specific intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: EdoxabaN or Warfarin Therapy In Device Procedures in Patients With Non-Valvular Atrial Fibrillation
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: DRUG: Edoxaban|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interactive Digital Technology to Assess and Improve Cognitive Dysfunction in Patients With Systemic Lupus Erythematosus
Status: UNKNOWN
Conditions: Lupus Erythematosus, Systemic
Interventions: DEVICE: Project EVO Multi- Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Thirdhand Smoke Contamination in a Neonatal Intensive Care Unit (NICU)
Status: COMPLETED
Conditions: Nicotine Exposure
Interventions: DRUG: 2% Chlorohexidine Gluconate soap|DRUG: 62% ethyl alcohol-based hand sanitizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Extended-Release Niacin/ Laropiprant/Simvastatin Tablets in Participants With Hypercholesterolemia or Mixed Dyslipidemia (MK-0524B-143)
Status: TERMINATED
Conditions: Primary Hypercholesterolemia|Mixed Dyslipidemia
Interventions: DRUG: ER niacin/laropiprant (ERN/LRPT)|DRUG: ER niacin/laropiprant/simvastatin (ERN/LRPT/SIM)|DRUG: Simvastatin (SIM)|DRUG: Placebo Run-In|DRUG: SIM-matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transconjunctival Sutureless 25-Gauge Vitrectomy
Status: COMPLETED
Conditions: Visual Acuity
Interventions: PROCEDURE: Multifocal IOL implantation + Vitrectomy|PROCEDURE: Multifocal IOL implantation - Vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center, Parallel Design, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of 6 and 12 mg Proellex® (Telapristone Acetate) Administered Orally in the Treatment of Premenopausal Women With Confirmed Symptomatic Uterine Fibroids
Status: COMPLETED
Conditions: Uterine Fibroids
Interventions: DRUG: Telapristone Acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
Status: RECRUITING
Conditions: Stroke|Stroke, Acute|Stroke, Ischemic|Stroke Hemorrhagic
Interventions: DIAGNOSTIC_TEST: Transcranial Magnetic Stimulation (TMS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Giving Information on the Risks and Limitations of Mammography Screening (GIRLS)
Status: UNKNOWN
Conditions: Breast Neoplasm
Interventions: OTHER: Full information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Semaglutide in HIV-Associated Lipohypertrophy
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV/AIDS|Lipohypertrophy|Obesity
Interventions: DRUG: Semaglutide Injectable Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of CAT-2054 in Combination With Atorvastatin in Patients With Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: CAT-2054|DRUG: Placebo|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Frequency of Superior Cluneal Nerve Entrapment Diagnosed With Ultrasound Guided Nerve Block
Status: COMPLETED
Conditions: Low Back Pain|Nerve Entrapment Syndrome|Radiating Pain
Interventions: DIAGNOSTIC_TEST: ultrasound-guided diagnostic nerve block with lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC