pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Evaluate the Efficacy and the Safety of Single Pill Combination (SPC) Ezetimibe/Rosuvastatin in Chinese Adult Patients With Primary Hypercholesterolemia Not Adequately Controlled on Statin Therapy
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Rosuvastatin|DRUG: SPC ezetimibe/rosuvastatin|DRUG: Rosuvastatin active capsule|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of 2 Different Techniques for Suppression of Respiratory Motion in Lung Cancer Treatment With Proton Therapy Using Magnetic Resonance Imaging (MRI)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: Deep Inspiration Breath Hold (DIBH)|OTHER: High Frequency Percussive Ventilation (HFPV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fluoxetine for Motor Recovery After Acute Intracerebral Hemorrhage
Status: TERMINATED
Conditions: Intracerebral Hemorrhage|Motor Impairment
Interventions: DRUG: Fluoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of ELDOA on Hamstring Tightness
Status: COMPLETED
Conditions: Non-specific Low Back Pain
Interventions: OTHER: Group A: Conventional Treatment + Elongation Longitudinaux Decoaption of Osteo-Articulaire|OTHER: Group B: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Difference Hydrodissection for CTS
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Ultrasound-guided short-axis hydrodissection with 5cc normal saline|PROCEDURE: Ultrasound-guided long-axis hydrodissection with 3cc normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of Methylprednisolone in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Children With AIDS
Status: WITHDRAWN
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Acute Myeloid Leukemia Post Cytotoxic Therapy|Juvenile Myelomonocytic Leukemia|Mixed Phenotype Acute Leukemia|Myelodysplastic Syndrome|Myelodysplastic Syndrome Post Cytotoxic Therapy|Myeloid Leukemia Associated With Down Syndrome
Interventions: PROCEDURE: Biospecimen Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Guo's Endovascular Aortic Arch Replacement of Aortic Dissection by WeFlow-Tribranch Endoprothesis: a Multicenter Pilot Study(GRAFT Study)
Status: RECRUITING
Conditions: Aortic Aneurysm and Dissection
Interventions: DEVICE: WeFlow-Tribranch Aortic Arch Stent Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Batten Grafting Improve Nasal Outcomes in Septoplasty and Turbinate Reduction?
Status: RECRUITING
Conditions: Nasal Obstruction|Septal Defect|Allergic Rhinitis|Nasal Polyps|Nasal Valve Collapse
Interventions: PROCEDURE: Batten batten graft|PROCEDURE: Septoplasty|PROCEDURE: Inferior Turbinate Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Use of Microneedle Patches to Deliver Topical Lidocaine in the Oral Cavity
Status: COMPLETED
Conditions: Topical Anaesthesia
Interventions: DEVICE: Microneedle Patch|DEVICE: Patch with no microneedles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Evaluating Safety of a New Catheter for Urinary Intermittent Catheter in Healthy Volunteers
Status: WITHDRAWN
Conditions: Spinal Cord Injury
Interventions: DEVICE: Intermittent catheterisation|DEVICE: NonCE marked intermittent catheter/red|DEVICE: NonCE marked intermittent catheter/green|DEVICE: NonCE marked intermittent catheter/blue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multi-Component Technology Intervention for Minority Emerging Adults With Asthma
Status: COMPLETED
Conditions: Asthma|Poor Medication Adherence
Interventions: BEHAVIORAL: Multi-component, technology based intervention|BEHAVIORAL: Asthma education active control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Safety and Immunogenicity of Quadrivalent Influenza Vaccine (7.5μg/0.25ml)
Status: COMPLETED
Conditions: Seasonal Influenza
Interventions: BIOLOGICAL: Quadrivalent influenza vaccine|BIOLOGICAL: Quadrivalent influenza vaccine|BIOLOGICAL: Trivalent influenza vaccine (contains B/Victoria strain)|BIOLOGICAL: Trivalent influenza vaccine (contains B/Yamagata strain)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Hemodynamic and Pharmacokinetic Analysis of Oxymetazoline Absorption
Status: COMPLETED
Conditions: Adenoidectomy|Functional Endoscopic Sinus Surgery (FESS)|Turbinate Surgery
Interventions: DRUG: Oxymetazoline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Genetic and Molecular Defects in Primary Immunodeficiency Disorders
Status: UNKNOWN
Conditions: X-Linked Agammaglobulinemia|X-Linked Hyper IgM Syndrome|Wiskott-Aldrich Syndrome|Leukocyte Adhesion Deficiency Syndrome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiofrequency Ablation for Warthin's Tumor
Status: COMPLETED
Conditions: Radiofrequency Ablation
Interventions: PROCEDURE: Ultrasound-guided Radiofrequency Ablation of Parotid Warthin's Tumor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Bovine Colostrum Versus Placebo in Treatment of Severe Alcoholic Hepatitis: A Randomized Double Blind Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcoholic Hepatitis
Interventions: DRUG: Bovine Colostrum|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Impact of EUS Elastography Mean Strain Histograms (SH) and Contrast Peak-enhancement in Focal Pancreatic Masses and Lymph Nodes
Status: COMPLETED
Conditions: Pancreatic Cancer|Secondary Malignant Neoplasm of Lymph Node|Benign Neoplasm of Lymph Nodes|Benign Pancreatic Tumors
Interventions: OTHER: Elastography, contrast enhancement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of INRS With BCSK in Children With Spastic Bilateral Cerebral Palsy: a Randomized Controlled Trial.
Status: COMPLETED
Conditions: Spastic Diplegia Cerebral Palsy
Interventions: PROCEDURE: BCSK|PROCEDURE: Traditional spinal manipulation|PROCEDURE: INRS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Randomized Trial of Proton vs. Photon Therapy for Patients With Non-Metastatic Breast Cancer: A Radiotherapy Comparative Effectiveness (RADCOMP) Consortium Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: Photon|RADIATION: Proton
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sipjeondaebo-tang for Cancer Related Anorexia in Cancer Patients
Status: COMPLETED
Conditions: Cancer-related Problem/Condition
Interventions: DRUG: SJDBT|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Daptomycin Versus Placebo in Patients With Neutropenia and Fever
Status: TERMINATED
Conditions: Febrile Neutropenia
Interventions: DRUG: Daptomycin|OTHER: Saline Placebo|DRUG: Daptomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Retromolar Route Access With and Without A Retromolar Gap
Status: COMPLETED
Conditions: Airway Management
Interventions: PROCEDURE: Retromolar laryngoscopy and scoring of the visualisation of the vocal cords according to Cormack & Lehane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Crenezumab Versus Placebo in Preclinical Presenilin1 (PSEN1) E280A Mutation Carriers to Evaluate Efficacy and Safety in the Treatment of Autosomal-Dominant Alzheimer's Disease (AD), Including a Placebo-Treated Non-Carrier Cohort
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Crenezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3, Controlled, Open-label, Global Randomized Study of RRx-001 With a Platinum Doublet or a Platinum Doublet in Small Cell Lung Cancer
Status: RECRUITING
Conditions: Carcinoma, Small Cell Lung
Interventions: DRUG: RRx-001 + eLOOP Device|DRUG: Cisplatin/carboplatin plus etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Colon Adenoma Detection Rate Using Two Distal Colonoscope Attachments
Status: COMPLETED
Conditions: Colon Cancer Screening|Colon Polyps|Colon Adenomas|Water Exchange Colonoscopy
Interventions: DEVICE: Olympus transparent cap|DEVICE: Medivators Endocuff|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pilot of Letrozole for Uterine Myomas
Status: COMPLETED
Conditions: Leiomyoma|Uterine Fibroids
Interventions: DRUG: Letrozole|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Durvalumab With Trastuzumab and Pertuzumab in HER2-Enriched Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Durvalumab|DRUG: Trastuzumab|DRUG: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of an Anti-HIV Drug Combination Taken Twice Daily
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Ritonavir|DRUG: Lamivudine|DRUG: Stavudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Oral Intake During Labor
Status: TERMINATED
Conditions: Labor Complication|Food Aspiration|Complication of Anesthesia|Satisfaction
Interventions: DIETARY_SUPPLEMENT: gastric soft/bland diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Dopaminergic Therapy in Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Rotigotine transdermal patch|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Vibrating Mesh Nebulizer Versus Jet Nebulizer in the Pediatric Asthma Patient
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: Jet Nebulizer|DEVICE: Vibrating Mesh Nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Talactoferrin in Adults With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Talactoferrin|PROCEDURE: Apheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Long Term Performance and Safety of the Knee Prosthesis (HLS KneeTec Deep Dish)
Status: TERMINATED
Conditions: Total Knee Arthroplasty|Knee Disease|Total Knee Replacement|Osteo Arthritis Knee
Interventions: DEVICE: HLS KneeTec Deep Dish
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Seroquel in Bipolar Depression Versus Lithium
Status: COMPLETED
Conditions: Bipolar Disorder|Bipolar Depression|Depression
Interventions: DRUG: Quetiapine Fumarate (Seroquel™) drug, mood stabilizer (mood)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of the Penumbra Coil 400 System to Treat Aneurysm
Status: COMPLETED
Conditions: Intracranial Aneurysms|Peripheral Aneurysms
Interventions: DEVICE: PC 400 coils (Penumbra )
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utility of Postoperative Bracing
Status: COMPLETED
Conditions: Postoperative Bracing for Spinal Deformity
Interventions: OTHER: Thoracolumbosacral (TLSO) brace|OTHER: No Bracing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Efficacy of Acupuncture on Patients With First Acute Ischemic Stroke, With Signs of Hemiplegia and Hemiparesis
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: real Acupuncture Needles|DEVICE: sham Acupuncture Needles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Single Dose and Steady State Pharmacodynamics of Biphasic Insulin Aspart 30 and 70 in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: biphasic insulin aspart 30|DRUG: biphasic insulin aspart 70
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Lapatinib in Combination With Everolimus in Patients With Advanced, Triple Negative Breast Cancer
Status: TERMINATED
Conditions: Breast Neoplasms|Breast Cancer|Cancer of the Breast
Interventions: DRUG: Lapatinib and Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of Profile of Hepatic Osteodystrophy in Patients With Non-Choleastatic Liver Cirrhosis and Impact of Bisphosphonate Supplementation
Status: COMPLETED
Conditions: Cirrhosis
Interventions: DRUG: Treated with Ibandronic acid as per protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Ten-Week Online Acceptance and Commitment Therapy Intervention for Family Caregivers of People With Dementia
Status: ACTIVE_NOT_RECRUITING
Conditions: Depressive Symptoms
Interventions: BEHAVIORAL: Acceptance and commitment therapy (ACT)|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comorbidities in Type 2 Diabetes Mellitus
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DIAGNOSTIC_TEST: HBA1C|DIAGNOSTIC_TEST: Lipid profile, including total, LDL, and HDL cholesterol and Triglycerides|DIAGNOSTIC_TEST: Urine analysis and urinary albumin-to-creatinine ratio|DIAGNOSTIC_TEST: Serum creatinine and estimated glomerular filtration rate|DIAGNOSTIC_TEST: Complete blood count|DIAGNOSTIC_TEST: Thyroid-stimulating hormone|DIAGNOSTIC_TEST: Serum iron, TIBC, Transferrin saturation and serum ferritin if needed|PROCEDURE: Electrocardiography (ECG)|PROCEDURE: Transthoracic echocardiography, Neck ultrasonography if needed and abdominopelvic ultrasound|PROCEDURE: Arterial duplex ultrasound of both lower limbs|DIAGNOSTIC_TEST: Random blood glucose|DIAGNOSTIC_TEST: AST, ALT, albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Total Neoadjuvant Treatment ±Immunotherapy for High Risk Locally Advanced Rectal Cancer (TNTi)
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: DRUG: Camrelizumab ＋Immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of an Oral Hygiene Implant Protocol
Status: TERMINATED
Conditions: Peri-implant Mucositis
Interventions: DEVICE: Water Flosser|DEVICE: Manual Toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety Study of Hemay005 in Subjects With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: 15mg Hemay005|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective, Open-Label, Single-Center, Non-Comparative Study to Assess the Use of Pixel CO2 Laser System (FemiLift) in the Treatment of Vulvovaginal Atrophy (VVA) in Postmenopausal Female Subjects
Status: COMPLETED
Conditions: Atrophy|Vaginal Atrophy|Genital Diseases, Female
Interventions: PROCEDURE: Pixel CO2 Laser System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Split-Belt Treadmill Perturbation in Children With Unilateral Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Split-belt treadmill training|OTHER: Standard physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors
Status: TERMINATED
Conditions: Locally Advanced or Metastatic Solid Tumor(s)|Prostate Cancer|Esophageal Cancer|Triple Negative Breast Cancer (TNBC)|Squamous Cell Carcinoma of Head and Neck (SCCHN)|Non-small Cell Lung Cancer (NSCLC)|Bladder Cancer|Uterine Cancer
Interventions: BIOLOGICAL: GEN1044 is an immunoglobulin G1 (IgG1) bispecific antibody targeting CD3 and 5T4.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerability and Safety of Subcutaneous Administration of AFFITOPE AD02 in Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: AFFITOPE AD02
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of H.P. Acthar Gel for the Treatment of Refractory Cutaneous Manifestations of Dermatomyositis
Status: COMPLETED
Conditions: Dermatomyositis|Juvenile Dermatomyositis
Interventions: DRUG: H.P. Acthar Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: C1-Esteraseremmer-N for the Treatment of Hereditary (and Acquired) Angioedema
Status: COMPLETED
Conditions: Angioedema
Interventions: DRUG: C1 inhibitor concentrate (C1-esteraseremmer-N)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Pharmacodynamic (PD) Effects of Once Weekly Administration of Gantenerumab in Participants With Early Alzheimer's Disease (AD)
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DRUG: Gantenerumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Copanlisib and Ketogenic Diet
Status: ACTIVE_NOT_RECRUITING
Conditions: Follicular Lymphoma|Endometrial Cancer
Interventions: DRUG: Copanlisib|OTHER: Ketogenic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding Patient Perspectives on the Risks of Ionizing Radiation Used for Medical Imaging
Status: COMPLETED
Conditions: Breast Cancer|Colon Cancer|Lung Cancer|Neuroblastoma|Testicular Cancer
Interventions: BEHAVIORAL: Focus Group Sessions|BEHAVIORAL: Focus Group Sessions|BEHAVIORAL: Focus Group Sessions|BEHAVIORAL: Focus Group Sessions|BEHAVIORAL: Focus Group Sessions|BEHAVIORAL: Focus Group Sessions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nasal Administration of Dexamethasone for Multiple Sclerosis (MS) Treatment
Status: WITHDRAWN
Conditions: MS Patient With Relpasing Remitting Attacks
Interventions: DRUG: Dexamethasone soduim phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Pain Management and Decreasing LOS After Total Hip Arthroplasty (THA) and Total Knee Arthroplasty (TKA)
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Respiratory Muscle Training and Respiratory Exercise in Exercise Tolerance, Performing Daily Life Activities and Quality of Life of Patients With Chronic Obstructive Pulmonary Disease
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Inspiratory muscle training|OTHER: Respiratory exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-demential Motoric Cognitive Risk Syndrome in Ageing Subjects
Status: RECRUITING
Conditions: Motoric Cognitive Risk Syndrome|Mild Cognitive Impairment|Alzheimer Disease|Dementia
Interventions: PROCEDURE: MRI evaluation|BEHAVIORAL: Actimetry & IMU|BEHAVIORAL: Gait evaluation|BEHAVIORAL: Neuropsychological evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of the Persistence of SARS-CoV-2 in the Olfactory Mucosa of Patients With Prolonged Symptoms of COVID-19
Status: RECRUITING
Conditions: SARS-CoV-2 Infection|Cognitive Disorder
Interventions: BIOLOGICAL: Nasopharyngeal swab for RT-PCR SARS-CoV-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Paper-Based and Smartphone-Based Memory Supports
Status: RECRUITING
Conditions: Alzheimer Disease|Dementia, Mild|Mild Cognitive Impairment
Interventions: BEHAVIORAL: Digital - Google Calendar|BEHAVIORAL: Paper-based - Memory Support System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Prospective Randomized Controlled Trial on the Use of Bone Morphogenetic 7 (BMP-7) (OP-1®) and Demineralized Bone Matrix in Tibial Non-union
Status: TERMINATED
Conditions: Non-union Diaphysary Tibial Fractures
Interventions: PROCEDURE: BMP-7 in adjunct to fresh frozen allograft|PROCEDURE: allograft together with DBM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of 4 Weeks Fish Oil Supplementation on Cycling Performance in Healthy Male Cyclists
Status: COMPLETED
Conditions: Exercise-induced Inflammation
Interventions: DIETARY_SUPPLEMENT: n-3 PUFA|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Consolidation Therapy With Brentuximab Vedotin After Allogeneic Stem Cell Transplantation for Relapsed or Refractory Hodgkin Lymphoma
Status: UNKNOWN
Conditions: Classical Hodgkin Lymphoma
Interventions: DRUG: Brentuximab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study of Bavituximab and Pembrolizumab in Advanced Gastric and GEJ Cancer Patients
Status: COMPLETED
Conditions: Gastric Cancer|GastroEsophageal Cancer
Interventions: DRUG: Bavituximab|DRUG: Pembrolizumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation
Status: TERMINATED
Conditions: Opioid-Induced Constipation
Interventions: DRUG: CB-5945|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Use of Gravitational Platelet Separation System on Leg Wound Healing in Coronary Bypass Surgery
Status: COMPLETED
Conditions: Coronary Heart Failure
Interventions: DEVICE: The GPS™ II Platelet Concentrate Separation Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Three Pulpotomy Agents for Permanent Mature Molars With Irreversible Pulpitis
Status: NOT_YET_RECRUITING
Conditions: Vital Pulp Therapy
Interventions: PROCEDURE: Full pulpotomy procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Renin-angiotensin System on Brain Activation During Hypoglycaemia in Healthy Men, a PET Study
Status: COMPLETED
Conditions: Hypoglycemia|Cognitive Impairment
Interventions: DRUG: Human insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Recto Anal Repair or Milligan Morgans Operation of Grade 3 and 4 Symptomatic Haemorrhoidal Disease
Status: TERMINATED
Conditions: Symptomatic Haemorrhoidal Disease
Interventions: PROCEDURE: Surgery for advanced haemorrhoidal disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiome Transplantation From Healthy Donors to Individuals With Fibromyalgia
Status: ENROLLING_BY_INVITATION
Conditions: Fibromyalgia
Interventions: OTHER: Fecal Microbiome Transplantation|OTHER: Sham Fecal Microbiome Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Family Intervention in Recent Onset Schizophrenia Treatment (FIRST)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: OTHER: Caregiver psycho-education and skills training|OTHER: Caregiver support available at the study site|DRUG: Paliperidone palmitate|DRUG: Chlorpromazine|DRUG: Droperidol|DRUG: Fluphenazine|DRUG: Haloperidol|DRUG: Loxapine|DRUG: Perphenazine|DRUG: Pimozide|DRUG: Prochlorperazine|DRUG: Thiothixene|DRUG: Thioridazine|DRUG: Trifluoperazine|DRUG: Aripiprazole|DRUG: Asenapine|DRUG: Clozapine|DRUG: Iloperidone|DRUG: Olanzapine|DRUG: Paliperidone|DRUG: Quetiapine|DRUG: Risperidone|DRUG: Ziprasidone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Identification of the Causative Drug in Drug-induced Acute Interstitial Nephritis
Status: UNKNOWN
Conditions: Acute Interstitial Nephritis|Drug-Induced Interstitial Nephritis
Interventions: OTHER: in vitro Allergological test Allergological skin tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: In-vitro and In-vivo Comparative Evaluation of Rotary Fanta and Zunba Files in Root Canal Preparation of Infected Primary Molars
Status: COMPLETED
Conditions: Root Canal Preparation of Infected Primary Molars
Interventions: PROCEDURE: root canal preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcomes and Data Collection for Fecal Microbiota Transplantation for the Treatment of Recurrent Clostridium Difficile
Status: RECRUITING
Conditions: Clostridium Difficile Infection Recurrence|Clostridium Difficile Infection
Interventions: PROCEDURE: Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CLN-619 (Anti-MICA/MICB Antibody) in Patients With Relapsed and Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: CLN-619
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Afatinib and Gemcitabine/Nab-paclitaxel in Metastatic Pancreatic Cancer
Status: UNKNOWN
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Afatinib 30Mg Tab|DRUG: Afatinib 40Mg Tab|DRUG: Gemzar|DRUG: Abraxane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Once Weekly D-cycloserine for Schizophrenia
Status: WITHDRAWN
Conditions: Schizophrenia
Interventions: DRUG: D-cycloserine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CPI-613 and Combination Chemotherapy in Treating Patients With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Acinar Cell Adenocarcinoma of the Pancreas|Duct Cell Adenocarcinoma of the Pancreas|Recurrent Pancreatic Cancer|Stage IV Pancreatic Cancer
Interventions: DRUG: 6,8-bis(benzylthio)octanoic acid|DRUG: oxaliplatin|DRUG: leucovorin calcium|DRUG: irinotecan hydrochloride|DRUG: fluorouracil|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Vitality Mammography Messaging Study
Status: COMPLETED
Conditions: Breast Cancer Female
Interventions: BEHAVIORAL: Standard message|BEHAVIORAL: Radiology booking site link.|BEHAVIORAL: Radiology practice telephone numbers|BEHAVIORAL: Radiology site link and telephone numbers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Clinical Trial of Upfront Haploidentical or Unrelated Donor BMT to Restore Normal Hematopoiesis in Aplastic Anemia
Status: NOT_YET_RECRUITING
Conditions: Severe Aplastic Anemia
Interventions: DRUG: Haploidentical donor bone marrow transplant|DRUG: Unrelated donor bone marrow transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Effect of Scaling and Root Planing on Liver Function Test (Alanine Aminotransferase and Aspartate Aminotransferase) in Systemically Healthy - Chronic Periodontitis Subjects: a Clinical Trial."
Status: COMPLETED
Conditions: Chronic Periodontitis (CP) Subjects.
Interventions: PROCEDURE: Scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Behavioral Economic Approaches to Increase Physical Activity Among Patients With Elevated Risk for Cardiovascular Disease
Status: COMPLETED
Conditions: Atherosclerotic Cardiovascular Disease
Interventions: BEHAVIORAL: Gamification|BEHAVIORAL: Financial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Examining a Digital Health Approach for Advancing Schizophrenia Illness Self-management and Provider Engagement
Status: COMPLETED
Conditions: Schizophrenia|Schizo Affective Disorder|Psychotic Disorders
Interventions: BEHAVIORAL: A4i Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Sleeve Gasterectomy With or Without Pyloric Botulinum Neurotoxin Injection
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: PROCEDURE: laparoscopic sleeve gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sunitinib Malate in Treating Patients With Thyroid Cancer That Did Not Respond to Iodine I 131 and Cannot Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Differentiated Thyroid Gland Carcinoma|Recurrent Thyroid Gland Carcinoma|Refractory Thyroid Gland Carcinoma|Stage III Thyroid Gland Follicular Carcinoma AJCC v7|Stage III Thyroid Gland Medullary Carcinoma AJCC v7|Stage IV Thyroid Gland Follicular Carcinoma AJCC v7|Stage IV Thyroid Gland Medullary Carcinoma AJCC v7|Stage IV Thyroid Gland Papillary Carcinoma AJCC v7|Stage IVA Thyroid Gland Follicular Carcinoma AJCC v7|Stage IVA Thyroid Gland Medullary Carcinoma AJCC v7|Stage IVA Thyroid Gland Papillary Carcinoma AJCC v7|Stage IVB Thyroid Gland Follicular Carcinoma AJCC v7|Stage IVB Thyroid Gland Medullary Carcinoma AJCC v7|Stage IVB Thyroid Gland Papillary Carcinoma AJCC v7|Stage IVC Thyroid Gland Follicular Carcinoma AJCC v7|Stage IVC Thyroid Gland Medullary Carcinoma AJCC v7|Stage IVC Thyroid Gland Papillary Carcinoma AJCC v7|Thyroid Gland Oncocytic Carcinoma|Unresectable Thyroid Gland Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacogenomic Study|DRUG: Sunitinib|DRUG: Sunitinib Malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma to Treat Plantar Fasciitis
Status: COMPLETED
Conditions: Plantar Fasciitis
Interventions: DEVICE: L-PRP Injection|DRUG: Corticosteroid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of MSC-EVs in the Prevention of BPD in Extremely Preterm Infants
Status: RECRUITING
Conditions: Bronchopulmonary Dysplasia
Interventions: BIOLOGICAL: Endotracheopulmonary Instillation, Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Placebo-controlled RCT of Botulinum Toxin A as a Treatment for Provoked Vestibulodynia
Status: COMPLETED
Conditions: Vulvodynia
Interventions: DRUG: Botulinum Toxin Type A|DRUG: Sterile Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telerehabilitation With Aims to Improve Lower Extremity Recovery Post-Stroke (TRAIL-RCT)
Status: RECRUITING
Conditions: Stroke|Stroke, Ischemic|Stroke Hemorrhagic|Cerebral Injury|Cerebral Infarction|Brain Diseases|Central Nervous System Diseases|Cerebral Vascular Accident|Cerebral Vascular Disorder|Brain Ischemia|Brain Infarction|Cardiovascular Diseases|Infarction
Interventions: OTHER: TRAIL|OTHER: EDUCATION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Gadobutrol 1.0 Molar in Japanese Subjects for CNS Imaging
Status: COMPLETED
Conditions: Magnetic Resonance Imaging
Interventions: DRUG: Gadobutrol (Gadovist, BAY86-4875)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study in Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Cetuximab|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy And Safety Study Of Atorvastatin Versus Simvastatin In Type 2 Diabetic Subjects With Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Atorvastatin|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Dolutegravir in HIV-infected Subjects With Treatment Failure on an Integrase Inhibitor Containing Regimen.
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: dolutegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Ondansetron in Post-op Cardiac Surgery Patients to Prevent Post-operative Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Ondansetron|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of a Single Vaccination of One of Three Ascending Dose Levels of a 4-Antigen Staphylococcus Aureus Vaccine (SA4Ag) and a Single Dose Level of a 3-Antigen Staphylococcus Aureus Vaccine (SA3Ag) in Healthy Adults Aged 65 to <86 Years
Status: COMPLETED
Conditions: Staphylococcal Infections
Interventions: BIOLOGICAL: SA4Ag vaccine low dose|PROCEDURE: Blood draw|PROCEDURE: Colonization swab sample|BIOLOGICAL: SA4Ag vaccine mid dose|PROCEDURE: Blood draw|PROCEDURE: Colonization swab sample|BIOLOGICAL: SA4Ag vaccine high dose|PROCEDURE: Blood draw|PROCEDURE: Colonization swab sample|BIOLOGICAL: SA3Ag vaccine|PROCEDURE: Blood sample|PROCEDURE: Colonization swab sample|BIOLOGICAL: Placebo|PROCEDURE: Blood draw|PROCEDURE: Colonization swab samples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Adductor Strengthening and Pelvic Floor Muscle Strengthening Exercises on Stress Incontinence in Gym Females
Status: COMPLETED
Conditions: Urinary Incontinence, Stress
Interventions: OTHER: Pelvic floor muscle plus adductor strengthening|OTHER: Pelvic floor muscle exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Autologous T-cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases in HIV-Infected Subjects
Status: COMPLETED
Conditions: HIV|HIV Infection
Interventions: BIOLOGICAL: SB-728-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Early L-Carnitine Supplementation on Neurodevelopmental Outcomes in Very Preterm Infants
Status: COMPLETED
Conditions: Prematurity|Neurodevelopmental Disorder|Carnitine Deficiency
Interventions: DRUG: L-carnitine|DRUG: 5% Dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Screening of Tobacco-induced Cancers by Low-dose CT-scanner and Identification of Circulating Tumor Cells
Status: ACTIVE_NOT_RECRUITING
Conditions: Tobacco|Cancer|Screening|Psychology|Lung
Interventions: DEVICE: medical imaging|BIOLOGICAL: Identification of Circulating Tumor Cells|PROCEDURE: Psychological Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Mitral Valve Repair Combined Coronary Artery Bypass Grafting(CABG) Verus CABG Alone on Functional Ischemic Mitral Regurgitation
Status: UNKNOWN
Conditions: Coronary Artery Disease|Mitral Valve Insufficiency
Interventions: PROCEDURE: CABG|PROCEDURE: mitral valve annuloplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Bepotastine Besilate Nasal Spray in the Treatment of Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Bepotastine Besilate Nasal Spray 2% Twice a day|DRUG: Bepotastine Besilate Nasal Spray 3% Twice a day|DRUG: Bepotastine Besilate Nasal Spray 4% Twice a day|DRUG: Placebo Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Internet Access and Use in Adolescent Women Initiating Contraception
Status: COMPLETED
Conditions: Contraceptive Behavior|Internet Use
Interventions: BEHAVIORAL: Using internet/E-mail for follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Fluorescent Cholangiography and Bile Duct Stones
Status: WITHDRAWN
Conditions: Gall Stones, Common Bile Duct
Interventions: DIAGNOSTIC_TEST: Presence of bile duct stones|DIAGNOSTIC_TEST: Non-presence of bile duct stones
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Reducing HIV Vulnerability Through A Multilevel Life Skills Intervention For Adolescent Men
Status: COMPLETED
Conditions: HIV Infections|Sexually Transmitted Diseases|Sexual Behavior|Adolescent Behavior|Homosexuality
Interventions: BEHAVIORAL: Life Skills Coaching|BEHAVIORAL: Community Resources
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Human Substance Balance and Biotransformation of [14C]SHR0302
Status: COMPLETED
Conditions: Rheumatoid Arthritis (RA)
Interventions: DRUG: SHR0302、[14C]SHR0302
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma
Status: TERMINATED
Conditions: Intraocular Melanoma|Melanoma (Skin)
Interventions: BIOLOGICAL: MART-1 antigen|BIOLOGICAL: gp100 antigen|BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: progenipoietin|BIOLOGICAL: tyrosinase peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Endodontic-Restorative Pre-Radiation Therapy of Head and Neck Cancer Patients
Status: WITHDRAWN
Conditions: Pulpitis - Irreversible|Caries|Head and Neck Cancer
Interventions: PROCEDURE: Root canal treatment and crown
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oleogel-S10 in Wound Healing of Inherited Epidermolysis Bullosa (BEB-10)
Status: COMPLETED
Conditions: Inherited Epidermolysis Bullosa
Interventions: DRUG: Oleogel-S10|DEVICE: Mepilex® soft silicone faced polyurethane foam dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validity and Reliability of Lower Extremity Position Test in Patients With Multiple Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis|Sensory Impairments|Proprioceptive Disorders|Validity|Reliability
Interventions: DIAGNOSTIC_TEST: Lower extremity position test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Compare Capsule and Tablet Forms of MDV3100 (Enzalutamide) After Administration of a Single Set Dose Under Fasted Conditions in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Subjects|Castration Resistant Prostate Cancer (CRPC)|Relative Bioavailability|MDV3100
Interventions: DRUG: MDV3100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase II Trial of Camrelizumab in Combination With Apatinib and Eribulin in Patients With Advanced TNBC
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Camrelizumab|DRUG: Apatinib|DRUG: Eribulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT