pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of Time Intervals for Rescue Treatment on Eradication Effect of Helicobacter Pylori Infection
Status: NOT_YET_RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: OTHER: Remedial treatment within 3 months|OTHER: Remedial treatment within 3 to 6 months|OTHER: Remedial treatment within 6 to 12 months|OTHER: Remedial treatment after 12 months
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Docetaxel, Gemcitabine and Pazopanib as Treatment for Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Stage III Adult Soft Tissue Sarcoma
Interventions: DRUG: Gemcitabine|DRUG: Docetaxel|DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BAY1003803 Formulation Comparison in Open Psoriasis Plaque Test
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: BAY1003803|DRUG: Clobetasol propionate|DRUG: Betamethasone/calcipotriene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Immunogenicity and Safety of Group A, C, Y & W-135 Meningococcal Polysaccharide Diphtheria Toxoid Conjugate Vaccine
Status: COMPLETED
Conditions: Meningococcal Meningitis|Meningococcal Infections
Interventions: BIOLOGICAL: Test Vaccine|BIOLOGICAL: US Licensed Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot PET Study of Regional Cerebral Protein Synthesis in Alzheimer's
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DIAGNOSTIC_TEST: [C11] Leucine PET scan|DIAGNOSTIC_TEST: [18F] Flutemetamol PET scan|DIAGNOSTIC_TEST: MRI scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MRX, Radiation, and Chemotherapy for Patients With Resected Squamous Cell Carcinoma of the Head and Neck
Status: TERMINATED
Conditions: Squamous Cell Carcinoma|Head and Neck Cancer|Resected Head and Neck Cancer|Mucositis
Interventions: DRUG: Oral MRX-1024|PROCEDURE: Standard Fractionation Radiation Therapy|DRUG: High-Dose Cisplatin Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Multi-Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of DFU and VLUs
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot Ulcer|Venous Leg Ulcer|Ulcer Foot|Leg Ulcer
Interventions: OTHER: Standard of Care-DFU|OTHER: AmnioCore - DFU|OTHER: Amnio Quad-Core - DFU|OTHER: Standard of Care-VLU|OTHER: Amnio Tri-Core - VLU|OTHER: AmnioCore Pro|OTHER: Amniocore Pro +
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrical Stimulation for the Treatment of Back Pain Using Peripheral Nerve Stimulation (PNS)
Status: COMPLETED
Conditions: Back Pain|Low Back Pain
Interventions: DEVICE: SPRINT Peripheral Nerve Stimulation (PNS) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fish Oil Study for High Triglyceride Levels in Children
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DRUG: Omega-3-acid ethyl esters|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phototherapy Applied in Association With Strength Training
Status: COMPLETED
Conditions: Muscle Development in Association to Phototherapy
Interventions: DEVICE: Active or Placebo Phototherapy (MR4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Inorganic Nitrate Supplementation on Cerebrovascular Aging and Arterial Stiffness Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Aging|Arterial Stiffness|Endothelial Dysfunction|Hypertension|Cognitive Decline
Interventions: DRUG: Experimental: Nitrate-containing|DRUG: Placebo: Nitrate-depleted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability, Pharmacokinetic and Pharmacodynamic Study With IZD334
Status: COMPLETED
Conditions: Healthy Volunteers|Cryopyrin Associated Periodic Syndrome
Interventions: DRUG: IZD334|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Use of Lapis Judaicus to Dissolve Kidney Stones
Status: COMPLETED
Conditions: Kidney Calculi
Interventions: DRUG: Lapis Judaicus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lanthanum Carbonate in Reducing Serum Phosphorus Levels in Subjects With Stage 3 and 4 Chronic Kidney Disease
Status: COMPLETED
Conditions: Kidney Diseases
Interventions: DRUG: Lanthanum carbonate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Volasertib and Belinostat in Patients With Relapsed and Refractory Aggressive B-cell and T-cell Lymphomas
Status: WITHDRAWN
Conditions: Relapsed and Refractory Aggressive B- and T-cell Lymphomas|Lymphoma
Interventions: DRUG: volasertib|DRUG: belinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph II OSI-774 (Erlotinib,Tarceva) In Advanced Bronchioloalveolar Cell Lung Cancer
Status: COMPLETED
Conditions: Bronchioloalveolar Cell Variant of Non-small Cell Lung Cancer
Interventions: DRUG: OSI-774: erlotinib, TarcevaTM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Plant-Based Protein and Marine-Based Multi-Mineral Supplement and Bone Remodeling in Young Adults
Status: COMPLETED
Conditions: Bone Resorption|Bone and Bones
Interventions: DIETARY_SUPPLEMENT: Combined Plant-Based Protein and Marine-Based Multi-Mineral Supplement|DIETARY_SUPPLEMENT: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: An Observational Study to Learn More About the Use of Androgen Receptor Inhibitors and How They Affect Men With Nonmetastatic Prostate Cancer in Routine Medical Care in the United States
Status: COMPLETED
Conditions: Non-metastatic Prostate Cancer|Non-metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Darolutamide (Nubeqa, BAY1841788)|DRUG: Enzalutamide|DRUG: Apalutamide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacodynamic of Ceftaroline and Levofloxacin Against Pathogens Associated With Community Acquired Bacterial Pneumonia
Status: COMPLETED
Conditions: Pneumonia, Bacterial|Community-acquired
Interventions: DRUG: Ceftaroline|DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Megestrol Acetate in Treating Weight Loss or Anorexia in Young Patients With Malignancies Who Are Undergoing Radiation Therapy and/or Chemotherapy
Status: TERMINATED
Conditions: Anorexia|Weight Changes
Interventions: DRUG: megestrol acetate|OTHER: clinical observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oxygen Toxicity in the Resuscitation in Extremely Premature Infants
Status: COMPLETED
Conditions: Birth Asphyxia|Premature Birth
Interventions: PROCEDURE: Resuscitation|PROCEDURE: Resuscitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Xeomin for Lower Limb Spasticity in Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Muscle Spasticity|Multiple Sclerosis
Interventions: BIOLOGICAL: incabotulinumtoxinA|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Proprioceptive Neuromuscular Proprioceptive Neuromuscular Facilitation
Status: COMPLETED
Conditions: Proprioceptive Neuromuscular Facilitation
Interventions: OTHER: eccentric exercises and electrical stimulation|OTHER: proprioceptive neuromuscular facilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Combined Administration of Sevoflurane and Remimazolam on Emergence
Status: RECRUITING
Conditions: Gynecological Surgery
Interventions: DRUG: Remimazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Influence of Smoking in Periodontitis Patients, Before and After Nonsurgical Treatment
Status: COMPLETED
Conditions: Periodontitis
Interventions: PROCEDURE: Nonsurgical periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Image-Guided Biopsies to Identify Mechanisms of Resistance in Patients With Metastatic Castration Resistant Prostate Cancer Treated With 177Lu-PSMA Radioligand Therapy
Status: RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Prostate Carcinoma|Stage IV Prostate Cancer American Joint Committee on Cancer (AJCC) v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: PROCEDURE: Image Guided Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Compare PK and Safety of CKD-381 and D026 in Healthy Male Subjects
Status: COMPLETED
Conditions: GERD
Interventions: DRUG: CKD-381(formulation I)|DRUG: CKD-381(formulation II)|DRUG: D026(Nexium 40mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Metoprolol in Patients With Hypertrophic Obstructive Cardiomyopathy.
Status: COMPLETED
Conditions: Hypertrophic Cardiomyopathy
Interventions: DRUG: Metoprolol Succinate|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)
Status: RECRUITING
Conditions: Migraine
Interventions: DRUG: Ubrogepant|DRUG: Placebo-Matching Ubrogepant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Proellex in Pre-menopausal Anemic Women With Symptomatic Uterine Fibroids
Status: TERMINATED
Conditions: Uterine Fibroids|Anemia
Interventions: DRUG: Proellex 25 mg|DRUG: Proellex 50 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Irinotecan in Treating Patients With Locally Advanced Unresectable or Metastatic Kidney Cancer
Status: TERMINATED
Conditions: Kidney Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intravenous to Oral 6-Day Tedizolid Phosphate vs. Intravenous to Oral 10-Day Linezolid in Patients With Acute Bacterial Skin and Skin Structure Infection (ABSSSI)
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: DRUG: Tedizolid (BAY119-2631)|DRUG: Placebo Tedizolid (BAY119-2631)|DRUG: Linezolid|DRUG: Placebo Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy of Pegolsihematide for Treatment of Anemia in Participants on Dialysis
Status: UNKNOWN
Conditions: Chronic Renal Failure|Anemia|Dialysis
Interventions: DRUG: pegol-Sihematide|DRUG: Epoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Increasing Dialysate Calcium on T50 in Subjects With Secondary Hyperparathyroidism and ESKD
Status: NOT_YET_RECRUITING
Conditions: Secondary Hyperparathyroidism|End-stage Kidney Disease
Interventions: OTHER: Dialysate calcium 1.50 mmol/L
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Control Trial of Buprenorphine vs. Morphine for the Treatment of Neonatal Opioid Withdrawal Syndrome (NOWS)
Status: WITHDRAWN
Conditions: Neonatal Opioid Withdrawal Syndrome
Interventions: DRUG: Buprenorphine or Placebo|DRUG: Morphine or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Effect of Dynamic Stretching With and Without Floss Band on Flexibility of Hamstrings in Futsal Players
Status: COMPLETED
Conditions: Sports Physical Therapy
Interventions: OTHER: Dynamic Stretching with Floss Band|OTHER: Dynamic Stretching without Floss Band
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Investigating the Safety and Immunogenicity of GBS6 in Pregnant Women With and Without HIV (PREPARE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Group B Streptococcal Infection
Interventions: DRUG: GBS6|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Wii Fit Based Exercises and Proprioceptive Exercises in Diabetic Neuropathy Patients
Status: COMPLETED
Conditions: Diabetic Neuropathies
Interventions: OTHER: baseline physical therapy treatment along with Wii Fit based exercises|OTHER: Proprioceptive exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2a Study of DaxibotulinumtoxinA-lanm for Injection in Dynamic Forehead Lines and Glabellar Lines
Status: RECRUITING
Conditions: Glabellar Frown Lines
Interventions: DRUG: DAXXIFY
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PegIntron Versus IntronA in CMAJCC Stage II (EADO 2001/CMII Trial)
Status: COMPLETED
Conditions: Melanoma|Neoplasm Metastasis
Interventions: DRUG: PegIntron|DRUG: intron A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin Gastrointestinal Intolerance: Measurement of Mitochondrial Complex I
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Metformin Adverse Reaction
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Laparoscopic Adjustable Gastric Banding as a Treatment for Morbid Obesity in Adolescents
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: DEVICE: Placement of an adjustable gastric band
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Stage III-IV or Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: Stage III Ovarian Epithelial Cancer|Stage III Ovarian Germ Cell Tumor|Stage IV Ovarian Epithelial Cancer|Stage IV Ovarian Germ Cell Tumor
Interventions: BIOLOGICAL: pUMVC3-hIGFBP-2 multi-epitope plasmid DNA vaccine|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant PD-1 Inhibitor Dostarlimab (TSR-042) vs. Combination of Tim-3 Inhibitor Cobolimab (TSR-022) and PD-1 Inhibitor Dostarlimab (TSR-042) in Melanoma
Status: RECRUITING
Conditions: Melanoma Stage III|Melanoma Stage IV
Interventions: DRUG: Dostarlimab (TSR-042) (singly)|DRUG: Dostarlimab (TSR-042) and TSR-022 (combination)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Animation, Buzzy, and Multiple Interventions on Pain in Children
Status: COMPLETED
Conditions: Pain, Procedural|Child|Phlebotomy|Venipuncture
Interventions: OTHER: Providing procedural informational animation video|DEVICE: Buzzy|COMBINATION_PRODUCT: Multiple interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Madany Closure: A Novel Technique for Fascial Closure in Laparoscopic Surgery
Status: RECRUITING
Conditions: Cholecystolithiasis
Interventions: PROCEDURE: Madany Closure|PROCEDURE: Standard closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Clinical Inertia in Diabetes Care
Status: COMPLETED
Conditions: Diabetes Mellitus|Hypertension|Hyperlipidemia
Interventions: BEHAVIORAL: Cognitive Behavioral Intervention|BEHAVIORAL: Office System Redesign Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Brexpiprazole (OPC-34712) Trial in the Treatment of Adults With Acute Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Brexpiprazole|DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study With RO5095932 in Patients With Type 2 Diabetes on Stable Metformin Therapy.
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Placebo|DRUG: Placebo|DRUG: RO5095932|DRUG: RO5095932
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Microneedling Therapy With or Without Amnion Bilayer Sheeting on Scar Tissue
Status: UNKNOWN
Conditions: Scars, Hypertrophic|Burn Scar
Interventions: PROCEDURE: Microoneedling and Amnion Bilayer|PROCEDURE: Microoneedling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Cerebellum in Speech
Status: RECRUITING
Conditions: Cerebellar Ataxia|Dysarthria|Healthy
Interventions: DIAGNOSTIC_TEST: MRI|DEVICE: TMS|BEHAVIORAL: Speech-motor behavioral testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: New Imaging Procedures and Therapeutic Approach in Basal Cell Carcinoma Management
Status: UNKNOWN
Conditions: Basal Cell Carcinoma
Interventions: DEVICE: Cynosure Cynergy Nd:YAG Laser 1064nm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare How Well Gadoquatrane Works and Its Safety With an Already Available Contrast Agent for MRI in People With Known or Suspected Brain or Spinal Cord-related Problems
Status: COMPLETED
Conditions: Contrast Enhancement in Magnetic Resonance Imaging|Central Nervous System Pathology
Interventions: DRUG: Gadoquatrane (BAY1747846)|DRUG: Gadobutrol|DRUG: Gadoterate meglumine|DRUG: Gadoteridol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Find Optimal Dose of Local Spinal Anesthetic (Mepivacaine) Combined With Narcotic (Fentanyl) For Knee Surgery
Status: COMPLETED
Conditions: Arthroscopic Knee Surgery
Interventions: PROCEDURE: Mepivacaine (24 mg) plus fentanyl|PROCEDURE: Mepivacaine (27 mg) plus fentanyl|PROCEDURE: Mepivacaine (30 mg) plus fentanyl|PROCEDURE: Mepivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stroke Rehabilitation: A Systemized and Hierarchized Rehabilitation Program for the Brazilian Unified Health System
Status: NOT_YET_RECRUITING
Conditions: Stroke, Ischemic
Interventions: OTHER: Innovative rehabilitation|OTHER: Conventional rehabilitation program.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Camelia Sinensis for Basal Metabolism and Body Composition
Status: UNKNOWN
Conditions: Postmenopausal Disorder
Interventions: DIETARY_SUPPLEMENT: Camellia Sinensis leaf extract|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Induction Chemotherapy and Toripalimab Followed by Chemoradiotherapy for Large-volume Local Advanced NSCLC
Status: RECRUITING
Conditions: Local Advanced Non-small Cell Lung Cancer
Interventions: DRUG: Toripalimab|RADIATION: Concurrent chemoradiation therapy and consolidation immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine Versus Etomidate During Rapid Sequence Intubation: Consequences on Hospital Morbidity
Status: COMPLETED
Conditions: Intubation; Difficult
Interventions: DRUG: Ketamine|DRUG: Etomidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Trial of Neoadjuvant Modified FOLFIRINOX Chemotherapy for Resectable Pancreatic Adenocarcinoma
Status: UNKNOWN
Conditions: Resectable Pancreatic Adenocarcinoma
Interventions: DRUG: neoadjuvant modified FOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antifungal Use in Oncohematological Neutropenic Patients
Status: COMPLETED
Conditions: Invader Fungal Infection
Interventions: DRUG: Antifungal drug. VORICONAZOL. (VFEND®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phenotype Evaluation in Insulin Naive Patients Using Lantus (Insulin Glargine)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Lantus (insulin glargine) + Glucophage (Metformin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CardiOvascular Risk and idEntificAtion of Potential High-risk Population in Acute Myocardial Infarction II (COREA-AMI II)
Status: UNKNOWN
Conditions: Acute Myocardial Infarction|Percutaneous Coronary Intervention|Major Adverse Cardiovascular Events|Bleeding
Interventions: PROCEDURE: Percutaneous coronary intervention|DRUG: Dual-antiplatelet therapy|PROCEDURE: Percutaneous coronary intervention|DRUG: Dual-antiplatelet therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison of Amethocaine Cream vs. Liposomal Lidocaine Cream for Venipuncture in Children.
Status: WITHDRAWN
Conditions: Pain
Interventions: DRUG: Ametop (4% Amethocaine cream )|DRUG: Maxilene (4% Liposomal Lidocaine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Methylation Level of SHOX2 in Endobronchial Ultrasound With Real-time Guided Transbronchial Needle Aspiration for Lung Cancer Staging
Status: COMPLETED
Conditions: Lung Cancer With Mediastinal Lymph Node Involvement
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Transcranial Direct Current Stimulation Associated With Aerobic Exercise Training for Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DEVICE: tDCS|PROCEDURE: active intervention of aerobic exercise|DEVICE: placebo tDCS|PROCEDURE: placebo AE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Right Hemicolectomy With Transrectal Specimen Extraction for Colon Cancer
Status: RECRUITING
Conditions: Colon Cancer
Interventions: PROCEDURE: Laparoscopic right hemicolectomy with transrectal specimen extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BLOSSOM: Behavioral Modification and Lorcaserin Second Study for Obesity Management
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Lorcaserin 10 mg once daily (QD)|DRUG: Lorcaserin 10 mg twice a day (BID)|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Control in Children and Adolescent After Thoracic Surgery: The Effect of Gabapentin
Status: COMPLETED
Conditions: Pain, Postoperative|Surgery, Thoracic
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Micronutrients in Combination With Usual Care in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Anti-oxidant and micronutrient|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Randomised Controlled Phase 1 Study of Vaccine Therapy for Control or Cure of Chronic Hepatitis B Virus Infection
Status: NOT_YET_RECRUITING
Conditions: Chronic Hepatitis b
Interventions: BIOLOGICAL: Therapeutic hepatitis B vaccine|BIOLOGICAL: Commercial Hepatitis B vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sex Steroids Balance for Metabolic and Reproductive Health in Klinefelter Syndrome
Status: RECRUITING
Conditions: Klinefelter Syndrome
Interventions: DRUG: Anastrozole|DRUG: Semaglutide|DRUG: human chorionic gonadotropin|DRUG: Testosterone gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ivor Lewis and Tri-incision Approaches for Patients With Esophageal Cancer
Status: UNKNOWN
Conditions: Surgical Procedures|Minimally Invasive|Operative|Esophageal Neoplasms|Cancer of Esophagus|Esophagectomy
Interventions: PROCEDURE: Ivor Lewis|PROCEDURE: Tri-incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of mFOLFIRINOX as Postoperative Chemotherapy for Pancreatic Cancer in Chinese Patients.
Status: COMPLETED
Conditions: Pancreatic Cancer Resectable
Interventions: DRUG: mFOLFORINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Administration as a Biological Adjuvant in Clinically-Staged, Resectable Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Resectable Pancreatic Adenocarcinoma|Pancreatic Cancer
Interventions: BIOLOGICAL: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of MeMed BV® on Management of Patients With Suspected Lower Respiratory Tract Infections (LRTI) in the Emergency Department (ED) and Urgent Care Center (UCC) ("JUPITER" TRIAL)
Status: RECRUITING
Conditions: Lower Respiratory Tract Infection
Interventions: DIAGNOSTIC_TEST: MeMed BV test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Examination of the Effect of Skin Antisepsis With Pre-heated Povidone Iodine on Surgical Site Infections: A Quasi-Experimental Study
Status: COMPLETED
Conditions: Surgical Site Infections
Interventions: DIAGNOSTIC_TEST: Follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: Enhancing Participation of Chronic Stroke Patients by Constraint Induced Movement Therapy (HOMECIMT)
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: mod. Constraint-Induced Movement Therapy|OTHER: Therapy as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study: Comparison of Patients' Knowledge of Direct Oral Anticoagulants in Post-hospitalization Between 2 Cardiology Departments Offering or Not a Pharmaceutical Interview During Hospitalization
Status: UNKNOWN
Conditions: Atrial Fibrillation|Deep Vein Thrombosis|Pulmonary Embolism
Interventions: OTHER: Phone interview
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combined Microfracture Procedure Promotes Tendon Healing
Status: RECRUITING
Conditions: Full Rotator Cuff Tear|Microfracture Procedure|Double Raw Repair
Interventions: PROCEDURE: microfracture procedure|PROCEDURE: only double raw repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Botox to Treat Neuropathic Pain
Status: COMPLETED
Conditions: Postherpetic Neuralgia|Nerve Trauma
Interventions: DRUG: botulinum toxin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability Study to Investigate and to Compare Two Different Formulations of Hyoscine Butylbromide in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Hyoscine butylbromide|DRUG: Hyoscine butylbromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery and Radiation Therapy With or Without Interleukin-2 in Treating Patients With Cancer of the Mouth or Oropharynx
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: aldesleukin|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Identification and Clinical Relevance of an Oxytocin Deficient State (GLP1 Study)
Status: RECRUITING
Conditions: Hypopituitarism|Central Diabetes Insipidus|Panhypopituitarism|Psychological Disorder|Social Isolation|Hypothalamic Diseases|Pituitary Diseases|Oxytocin Deficiency
Interventions: DRUG: Experimental: GLP1-RA (exenatide) administration|DRUG: Control: Placebo administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Reduced PCV Dosing Schedules in South African Infants
Status: COMPLETED
Conditions: Pneumonia|Meningitis
Interventions: BIOLOGICAL: Pneumococcal conjugate vaccine (PCV10 ) 1+1, 6 weeks|BIOLOGICAL: Pneumococcal conjugate vaccine (PCV10 ) 1+1, 14 weeks|BIOLOGICAL: Pneumococcal conjugate vaccine (PCV10 ) 2+1|BIOLOGICAL: Pneumococcal conjugate vaccine (PCV13 ) 1+1, 6 weeks|BIOLOGICAL: Pneumococcal conjugate vaccine (PCV13 ) 1+1, 14 weeks|BIOLOGICAL: Pneumococcal conjugate vaccine (PCV13 ) 2+1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of an Anti-OX40 Monoclonal Antibody (KHK4083) in Subjects With Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: KHK4083|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ambroxol Spray Sore Throat Study
Status: COMPLETED
Conditions: Pharyngitis|Pain
Interventions: DRUG: Ambroxol Spray|DRUG: Ambroxol Spray|DRUG: Ambroxol Spray|DRUG: Placebo Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Modified Technique of Free Gingival Graft in Volumetric Changes of the Graft: Randomized Clinical Trial
Status: UNKNOWN
Conditions: Gingival Recession
Interventions: PROCEDURE: Free Gingival Graft|PROCEDURE: Original Free Gingival Graft technique|PROCEDURE: Modified Free Gingival Graft technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of Intranasal Oxytocin on Chronic Pain
Status: RECRUITING
Conditions: Chronic Pain
Interventions: DRUG: 24-IU oxytocin|DRUG: 48-IU oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of the Tool " iPSC " for the Functional Study of Mutations Responsible for Mental Retardation
Status: COMPLETED
Conditions: Intellectual Deficiency|Asymptomatic Carrier of the Mutation of the Gene MYT1L|Healthy Volunteers
Interventions: PROCEDURE: Cutaneous biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: N-acetylcysteine (NAC) for the Treatment of Acute Exacerbation of COPD
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: N-acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Atropine to Atropine Plus a Plano Lens for the Sound Eye for Amblyopia in Children 3 to <7 Years Old
Status: COMPLETED
Conditions: Amblyopia
Interventions: DRUG: Atropine|DEVICE: Plano Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of SHR-1905 in Healthy Subjects and Subjects With Mild Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: DRUG: SHR-1905/placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine/Oxaliplatin (GEMOX) vs Carboplatin/Paclitaxel (CP) in Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: gemcitabine/Eloxatin (GEMOX)|DRUG: carboplatin/paclitaxel (CP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Magnetic Resonance-guided High Intensity Focused Ultrasound for the Ablation of Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer, Invasive Ductal
Interventions: DEVICE: Philips Sonalleve® MR-HIFU Breast Therapy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acetaminophen Versus IV Hydromorphone for Pain in the Elderly in the ED
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Acetaminophen 1000mg IV|DRUG: Hydromorphone 0.5 mg IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ravulizumab in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria Currently Treated With High-Dose Eculizumab
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: BIOLOGICAL: Eculizumab|BIOLOGICAL: Ravulizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RAdiotherapy With FDG-PET Guided Dose-PAINTing Compared With Standard Radiotherapy for Primary Head and Neck Cancer-3
Status: RECRUITING
Conditions: Head and Neck Cancer|Radiotherapy Side Effect
Interventions: RADIATION: Dose painting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells and Amniotic Membrane Composite for Supraspinatus Tendon Repair Augmentation
Status: UNKNOWN
Conditions: Supraspinatus Tear
Interventions: PROCEDURE: Tendon repair procedure|PROCEDURE: Tendon repair augmented with AAdMSC-HAM composite
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Diet Effect on Cancer Treatment Outcome
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer Breast|Cancer Prostate
Interventions: DIETARY_SUPPLEMENT: Dietary Supplement: N-111|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: European Prospective Registry on Anomalous Aortic Origin of the Coronary Arteries
Status: RECRUITING
Conditions: Congenital Heart Disease|Coronary Artery Anomaly|Sudden Cardiac Death|Surgical Procedure, Unspecified|Diagnosis|Arrhythmia|Heart Defects, Congenital|Adult Children
Interventions: PROCEDURE: unroofing or other surgery if needed
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cervical Spinal Cord Stimulation in Patients With Cerebral Vasospasm After Subarachnoid Haemorrhage: VasoStim Study
Status: RECRUITING
Conditions: Cerebral Vasospasm|Subarachnoid Hemorrhage
Interventions: DEVICE: Spinal cord stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparision of PVC Ablation Techniques
Status: UNKNOWN
Conditions: Premature Ventricular Contraction
Interventions: DEVICE: Radiofrequency Ablation Catheter|DEVICE: Cryo Ablation catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Care Bundle in Preventing Medical Adhesive-Related Skin Injury Due to Central Venous Catheter Fixation in Children
Status: NOT_YET_RECRUITING
Conditions: Skin Injury
Interventions: OTHER: SECURE Care Bundle|PROCEDURE: Standart Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of the Music With Structured Verbal Training During Prostate Biopsy
Status: COMPLETED
Conditions: Pain|Anxiety|Satisfaction|Urological Nursing
Interventions: OTHER: Music with Structured Verbal Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Viusid and Asbrip in Hospitalized Patients With Mild and Moderate COVID-19
Status: COMPLETED
Conditions: Covid19|Respiratory Disease|Immune System|Immunomodulator|Antiseptic|Supportive Care
Interventions: DIETARY_SUPPLEMENT: Viusid|DIETARY_SUPPLEMENT: Asbrip|DRUG: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Glumetinib Combined With Toripalimab in the Treatment of Relapsed or Metastatic Non-small Cell Lung Cancer.
Status: UNKNOWN
Conditions: Relapsed or Metastatic Non-small Cell Lung Cancer
Interventions: COMBINATION_PRODUCT: Glumetinib combined with Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Efficacy Of Enbrel (REGISTERED) Etanercept Over A Period Of 12 Months In The Routine Treatment Of Patients With Rheumatoid Arthritis, Axial Spondyloarthritis, Psoriatic Arthritis, Or Plaque Psoriasis.
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Psoriatic Arthritis|Axial Spondyloarthritis|Plaque Psoriasis
Interventions: DRUG: Etanercept
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dabigatran Versus Rivaroxaban in Cerebral Venous Thrombosis
Status: RECRUITING
Conditions: Cerebral Venous Sinus Thrombosis
Interventions: DRUG: Dabigatran Etexilate 150mg|DRUG: Rivaroxaban 20 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glycemia and Ischemia Reperfusion Brain Injury in Patients With Acute Cerebral Infarction Treated With Mechanical Thrombectomy
Status: RECRUITING
Conditions: Cerebral Infarction
Interventions: DEVICE: Subcutaneous blood glucose monitoring device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Short Term Bed Rest Study: Evaluation of the Use of Artificial Gravity, Induced by Short-arm Centrifugation
Status: COMPLETED
Conditions: Bone Diseases, Metabolic|Acid-Base Imbalance|Muscular Atrophy|Sprains and Strains|Protein Metabolism|Body Weight Changes|Cardiovascular Abnormalities
Interventions: OTHER: Defined Training Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cardiac Steatosis in Cushing's Syndrome
Status: UNKNOWN
Conditions: Endocrine System Disease|Cardiovascular Imaging
Interventions: OTHER: 1H magnetic resonance spectroscopy and CMRI|OTHER: 1H magnetic resonance spectroscopy and CMRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Neuromuscular Integrative Activity and Pilates on Sedentary Females
Status: COMPLETED
Conditions: Womens's Health|Healthy|Sedentary Behavior
Interventions: OTHER: Pilates|OTHER: Neuromuscular Integrative Action
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety and Efficacy Study of Multiple Tyrosine Kinase Inhibitor Drug (ETN101) in Advanced Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Advanced Hepatocellular Carcinoma|Liver Cancer
Interventions: DRUG: ETN101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concordance Between the Measurement of Whole Blood Fibrinogen by the qLabs®FIB Analyzer and Its Measurement by Conventional Method (Clauss Fibrinogen) in the Context of Severe Postpartum Haemorrhage
Status: NOT_YET_RECRUITING
Conditions: Postpartum Hemorrhage
Interventions: BIOLOGICAL: Fibrinogen concentration by the qLabs®FIB Monitoring system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Compare the Effect of Inhaled Insulin With Subcutaneously Injected Insulin in Subjects With Type 2 Diabetes Mellitus.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Technosphere/Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OCS-01 in Treating Inflammation and Pain in Post-cataract Patients
Status: COMPLETED
Conditions: Inflammation Corneal|Pain, Postoperative
Interventions: DRUG: OCS-01 - Dexamethasone Cyclodextrin Nanoparticle Ophthalmic Suspension 1.5% mg/mL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Efficacy of AUR107 in Patients With Relapsed Advanced Malignancies (SHAKTI-1)
Status: RECRUITING
Conditions: Relapsed Malignant Solid Neoplasm
Interventions: DRUG: AUR107
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT