pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Endoscopic Sleeve Gastroplasty for Obesity and Microbiota Randomized Trial
Status: RECRUITING
Conditions: Obesity|Endoscopic Sleeve Gastroplasty|Gastric Motility|Gastric Hormones|Microbiota|Quality of Life
Interventions: DEVICE: Endoscopic sleeve gastroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Compare Survival for ASTRA TECH Implant System, OsseoSpeed™ Implants Following Immediate Loading in Extraction Sockets Versus Immediate Loading in Healed Ridges
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially
Interventions: DEVICE: ASTRA TECH Implant System, OsseoSpeed™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oleanolic Acid as Therapeutic Adjuvant for Type 2 Diabetes Mellitus (OLTRAD STUDY)
Status: RECRUITING
Conditions: Diabetic Patients|Type II Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: OA-enriched functional olive oil|DIETARY_SUPPLEMENT: commercial olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electroacupuncture of Different Treatment Frequency in Chronic Urinary Retention Caused by Lower Motor Neuron Lesions
Status: RECRUITING
Conditions: Urinary Retention|Lower Motor Neurone Lesion
Interventions: DEVICE: Electroacupuncture of 2 sessions per week|DEVICE: Electroacupuncture of 3 sessions per week|DEVICE: Electroacupuncture of 4 sessions per week
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reducing Heavy Drinking to Optimize HIV/AIDS Treatment and Prevention
Status: COMPLETED
Conditions: Reduction in Heavy Drinking in Patients With HIV
Interventions: DRUG: Naltrexone|OTHER: Placebo + Medication Management/Medication Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Valproate Dose Reduction and Its Clinical Evaluation by Introducing Lamotrigine in Japanese Women With Epilepsy - Single Arm, Multicenter, and Open-label Study
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Lamotrigine tablets 25/100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnesium Sulphate and Sevoflurane Induced Emergence Agitation in Children
Status: UNKNOWN
Conditions: Emergence Delirium|Postopertive Delirium|Emergence Agitation in Children
Interventions: DRUG: Magnesium Sulfate|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: An Exploratory Clinical Study Evaluating the Safety and Efficacy of Intravenous Anti-CD20/CD30-CAR-T Cell Infusion in Relapsed/Refractory Lymphoma Patients.
Status: NOT_YET_RECRUITING
Conditions: B Cell Malignancies
Interventions: BIOLOGICAL: anti-CD20/CD30-CAR-T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of MetMAb Combined With Tarceva in Patients With Met-Positive Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: erlotinib [Tarceva]|DRUG: Placebo|DRUG: Onartuzumab [MetMAb]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Medtronic Gatekeeper System in the Treatment of SUBJECTS With Gastroesophageal Reflux Disease (GERD)
Status: TERMINATED
Conditions: Gastroesophageal Reflux Disease
Interventions: DEVICE: Gatekeeper Reflux Repair System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Follow-up Study After ACLSCT for Restoration of Corneal Epithelium in Patients With LSCD Due to Ocular Burns
Status: COMPLETED
Conditions: Limbal Stem Cell Deficiency Due to Ocular Burn
Interventions: PROCEDURE: Ophthalmologic examinations|OTHER: Digital pictures|OTHER: QoL Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Binge Eating Disorder in Obesity: Naltrexone/ Bupropion Combination Versus Placebo
Status: COMPLETED
Conditions: Binge Eating Disorder
Interventions: DRUG: Naltrexone and bupropion combination|OTHER: Pill Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ALXN1007 in Healthy Male and Female Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: ALXN1007
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of TG103 Produced by Two Manufacturing Processes in Chinese Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Male Subjects
Interventions: DRUG: TG103 produced by the modified manufacturing process|DRUG: TG103 produced by the original manufacturing process
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Study in Children and Adolescents With Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Chronic Severe Plaque-type Psoriasis
Interventions: BIOLOGICAL: Experimental : Secukinumab low dose|BIOLOGICAL: Experimental: Secukinumab high dose|BIOLOGICAL: Placebo Comparator: Secukinumab Placebo|BIOLOGICAL: Active Comparator: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Video Training to Reduce Insulin Administration Errors
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Insulin Injection Pad|Injection Site|Insulin Implementation Errors|Educational Problems
Interventions: BEHAVIORAL: Video group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Infectious Aetiology of Potentially Malignant Disorders and Squamous Cell Carcinomas of the Oral Cavity
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Oral Cavity|Leukoplakia Oral
Interventions: PROCEDURE: contralateral healthy tissue biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Effect of a Very Low Carbohydrate Diet on Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease|Overweight|Acid Reflux Disease
Interventions: OTHER: Diet - very low carb or low fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SWEET: Once Daily Truvada Versus Twice Daily Combivir for the Treatment of HIV Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: zidovudine and lamivudine (Combivir®)|DRUG: emtricitabine and tenofovir DF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Octreotide Improves Human Lymphatic Fluid Transport a Translational Trial
Status: COMPLETED
Conditions: Lymphatic Diseases|Chylothorax
Interventions: DRUG: Octreotide infusion|DRUG: Saline infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mosunetuzumab and Polatuzumab Vedotin for the Treatment of Patients With Relapsed or Refractory Grade 1-3a Follicular Lymphoma
Status: RECRUITING
Conditions: Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3a Follicular Lymphoma|Refractory Grade 1 Follicular Lymphoma|Refractory Grade 2 Follicular Lymphoma|Refractory Grade 3a Follicular Lymphoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Mosunetuzumab|DRUG: Polatuzumab Vedotin|PROCEDURE: Positron Emission Tomography|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fournier's Gangrene and the Origin of the Infection as a Prognostic of Morbidity and Mortality, an Analysis of 121 Patients
Status: COMPLETED
Conditions: Fournier Gangrene|Fournier's Gangrene of Penis|Fournier's Gangrene of Scrotum
Interventions: PROCEDURE: Aggressive debridement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial of TQC3721 Suspension for Inhalation in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: 3mg TQC3721 Suspension for Inhalation|DRUG: 6mg TQC3721 Suspension for Inhalation|DRUG: Placebo TQC3721 suspension for inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tacrolimus Versus Cyclosporine for Immunosuppression After Lung Transplantation
Status: COMPLETED
Conditions: Bronchiolitis Obliterans|Immunosuppression
Interventions: DRUG: Tacrolimus|DRUG: Cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: GSK2190915 Pediatric Study
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: GSK2190915A 5mg|DRUG: GSK2190915A 10mg|DRUG: GSK2190915A 25mg|DRUG: GSK2190915A 50mg|DRUG: GSK2190915A 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transfusion Triggers in Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Surgery
Interventions: PROCEDURE: Transfusion with Red Blood Cells|BIOLOGICAL: 1 unit of donated red blood cells|BIOLOGICAL: 1 unit of donated red blood cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Paravertebral Block on Postoperative Quality of Recovery After Hepatectomy
Status: COMPLETED
Conditions: Nerve Block
Interventions: PROCEDURE: Continuous Paravertebral block with ropivacaine|PROCEDURE: Continuous Paravertebral Block with Saline|DRUG: Patient-controlled analgesia with morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bioequivalence Study of Amlodipine/Valsartan 10/160 mg Film Coated Tablets
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteer
Interventions: DRUG: Amlodipine/Valsartan|DRUG: Amlodipine 10 mg &valsartan 160 mg (Exforge)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Two Part Study of Peroral Insulin in Type 2 Diabetes
Status: SUSPENDED
Conditions: Diabetes Mellitus
Interventions: DRUG: Insulin in Dextran Matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Uterine Artery Doppler and Menstrual Changes After Insertion Intrauterine Contraceptive Device
Status: NOT_YET_RECRUITING
Conditions: Intrauterine Contraceptive Device Complication
Interventions: DEVICE: Copper intrauterine contraceptive device|DEVICE: LNG-IUS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Study of the Efficacy and the Safety of Flumatinib vs Imatinib as First Line Treatment in Patients With CML
Status: COMPLETED
Conditions: CML, CML-CP,MMR,TKI
Interventions: DRUG: Flumatinib 600mg qd|DRUG: Imatinib 400mg qd
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Training Community Members to Deliver HIV Prevention Programs to Urban Youth
Status: COMPLETED
Conditions: HIV|HIV Infections
Interventions: BEHAVIORAL: Be Proud! Be Responsible!|BEHAVIORAL: Becoming A Responsible Teen (BART)|BEHAVIORAL: Reducing the Risk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Growth Hormone Pretreatment in Poseidon Type IV Undergoing ICSI Using Minimal Induction Protocol: A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Poor Response to Ovulation Induction Poseidon Type IV
Interventions: DRUG: Growth Hormone|DRUG: Clomiphene citrate daily and recombinant FSH (Gonal-F®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Power Lung Versus Acapella After Coronary Artery Bypass Graft Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Bypass Graft Surgery
Interventions: DEVICE: Acapella device|DEVICE: Power lung device|OTHER: routine Physical Therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Vildagliptin in Combination With Glimepiride in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: vildagliptin|DRUG: Glimepiride|DRUG: LAF237 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of PrTMS on Performance
Status: WITHDRAWN
Conditions: Sleep Quality|Cognition Improvement
Interventions: DEVICE: PrTMS|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I Dose Escalation Trial of Volasertib in Combination With Azacitidine in Patients With MDS or CMML
Status: TERMINATED
Conditions: Myelodysplastic Syndromes|Leukemia, Myelomonocytic, Chronic
Interventions: DRUG: Azacitidine|DRUG: Volasertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Percutaneous Radiofrequency Ablation of Primary and Secondary Lung Tumors
Status: COMPLETED
Conditions: Lung Cancer|Lung Metastasis
Interventions: PROCEDURE: pulmonary radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acetaminophen vs Indomethacin in Treating hsPDA
Status: TERMINATED
Conditions: Patent Ductus Arteriosus
Interventions: DRUG: Indomethacin|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OLAParib COmbinations
Status: TERMINATED
Conditions: Cancer
Interventions: DRUG: AZD2281|DRUG: AZD5363|DRUG: AZD1775|DRUG: AZD6738
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Effects on Blood Glucose Following Intradermal and Subcutaneous Dosing of Insulin in Diabetic Patients
Status: COMPLETED
Conditions: Diabetes
Interventions: DEVICE: BD Research Catheter with 34G x 1.5 mm needle|DEVICE: Subcutaneous delivery of insulin using Disetronic Accu-Chek Rapid D infusion set
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sacral Neuromodulation in Neurogenic Patients
Status: ENROLLING_BY_INVITATION
Conditions: Neurogenic Bladder|Neurogenic Bowel|Urge Incontinence|Overactive Bladder|Retention, Urinary|Fecal Incontinence
Interventions: DEVICE: InterStim II
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Self-Management in Parents of Technology-Dependent Children
Status: COMPLETED
Conditions: Caregivers|Parents|Self-Management|Chronic Illnesses, Multiple
Interventions: BEHAVIORAL: Resourcefulness Training©
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Famciclovir 500 mg Tablets Under Non-Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Famciclovir 500 mg Tablets|DRUG: Famvir® 500 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pilot Study of Raltegravir/Truvada Versus Efavirenz/Truvada for Adults With Acute IV-1 Infection
Status: COMPLETED
Conditions: Acute HIV Infection
Interventions: DRUG: Raltegravir|DRUG: Efavirenz|DRUG: Emtricitibine|DRUG: Tenofovir disoproxil once daily|DRUG: Tenofovir disoproxil twice daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Targeting of Stress Factors in Ovarian Cancer Patients
Status: COMPLETED
Conditions: Invasive Epithelial Ovarian Cancer|Primary Peritoneal Carcinoma|Fallopian Tube Cancer
Interventions: DRUG: Propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Effects of Varying Fat:Carbohydrate Diet Permutations on Gastric Emptying and Metabolic Status Using Human Postprandial Model
Status: RECRUITING
Conditions: Postprandial Lipemia|Postprandial Glycemia|Gastric Emptying
Interventions: OTHER: HGI+palm olein|OTHER: LGI+palm olein|OTHER: HGI+soy bean oil|OTHER: LGI+soy bean oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of Pelvis Diameters as a Predictor for the Mode of Delivery ,Using Non-invasive, Ultrasound Based Measurements
Status: UNKNOWN
Conditions: Pregnancy|Women
Interventions: DEVICE: pelvic measurements using the LaborPro Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Increased Cefazolin During Cesarean Delivery in Obese Population
Status: COMPLETED
Conditions: Obesity|Obesity, Morbid|Pregnancy|Infection; Cesarean Section
Interventions: DRUG: Cefazolin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of Carbidopa/Levodopa/Entacapone Combination vs. Carbidopa/Levodopa Combination Plus Entacapone Under Fasting Conditions in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ELC200 (carbidopa+levodopa+entacapone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MK0928 Study in Adult Patients With Primary Insomnia (0928-040)(COMPLETED)
Status: COMPLETED
Conditions: Primary Insomnia
Interventions: DRUG: MK0928, gaboxadol / Duration of Treatment 3 Weeks|DRUG: Placebo / Duration of Treatment 3 Weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Client-Centered Care Coordination for Black Men Who Have Sex With Men
Status: NOT_YET_RECRUITING
Conditions: HIV Prevention|HIV Pre-exposure Prophylaxis
Interventions: BEHAVIORAL: Client Centered Care Coordination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Feasibility, Acceptability, and Preliminary Efficacy of a Novel Personalized Mobile Intervention for Suicide - Open Trial (2)
Status: RECRUITING
Conditions: Suicide|Suicide and Self-harm|Suicide, Attempted|Suicidal Ideation
Interventions: BEHAVIORAL: Mobile Application to Prevent Suicide (MAPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infant-parent Skin-to-skin Contact During Screening for Retinopathy
Status: COMPLETED
Conditions: Retinopathy of Prematurity
Interventions: BEHAVIORAL: skin-to-skin contact|DEVICE: incubator|DRUG: Sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Opioids and NSAIDs on Sympathetic Nervous System and Vascular Function
Status: RECRUITING
Conditions: Osteoarthritis of Multiple Joints of Ankle or Foot|Healthy
Interventions: DRUG: Tramadol|DRUG: Paracetamol|DRUG: Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Everolimus in Combination With Exemestane Versus Everolimus Alone Versus Capecitabine in Advance Breast Cancer.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Capecitabine|DRUG: Exemestane|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare How Much Solifenacin Succinate and Mirabegron Reach the Blood When Administered Together as Fixed-dose Combination Tablets and With Single Individual Tablets of the Same Medications at Three Dose Levels
Status: COMPLETED
Conditions: Phase 1|Bioavailability|Healthy Subjects
Interventions: DRUG: solifenacin succinate|DRUG: mirabegron|DRUG: mirabegron/solifenacin succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Trial of Oral Vancomycin Therapy vs. Placebo for Prevention of CDI
Status: WITHDRAWN
Conditions: CDI
Interventions: DRUG: Vancomycin 125 MG po BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Interest of the Instillation of Saline Intraperitoneally (INSI ) Versus Instillation of Naropin the Surgical Site Versus Lung Recruitment Maneuvers ( PVM ) in the Management of Pain After Laparoscopic Cholecystectomy in Ambulatory Care
Status: WITHDRAWN
Conditions: Surgery|Pain
Interventions: DRUG: Sodium chloride administration|DRUG: Ropivacaine administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Postprandial Liver and Spleen Stiffness Measurements in the Noninvasive Diagnosis of Cirrhosis
Status: COMPLETED
Conditions: Chronic Liver Disease
Interventions: DEVICE: Fibroscan and Acoustic Radiation Force Impulse|DEVICE: Fibroscan|DEVICE: Acoustic Radiation Force Impulse
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Safety and Efficacy of an Oxalate Strip on Adjacent Teeth With Dentinal Hypersensitivity
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: DEVICE: Crest® Sensi-Stop™ Strips
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlled Trial Of Acupuncture To Prevent Radiation-Induced Xerostomia
Status: ACTIVE_NOT_RECRUITING
Conditions: Head And Neck Cancer
Interventions: PROCEDURE: Acupuncture - Group 1|PROCEDURE: Acupuncture - Group 2|OTHER: Standard Care|OTHER: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Allogeneic Hematopoietic Stem Cell Transplant For Epidermolysis Bullosa
Status: TERMINATED
Conditions: Epidermolysis Bullosa
Interventions: DRUG: busulfan|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|PROCEDURE: hematopoietic bone marrow transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Botensilimab and Balstilimab for the Treatment of Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Botensilimab|DRUG: Balstilimab|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NSAID Use After Robotic Partial Nephrectomy
Status: RECRUITING
Conditions: Kidney Cancer|Renal Cancer|Renal Neoplasm
Interventions: DRUG: Ketorolac|DRUG: Acetaminophen|DRUG: Oxycodone|DRUG: Hydromorphone|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Platine, Avastin and OLAparib in 1st Line
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Olaparib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Routine Aspiration Thrombectomy With Percutaneous Coronary Intervention (PCI) Versus PCI Alone in Patients With ST-Segment Elevation Myocardial Infarction (STEMI) Undergoing Primary PCI
Status: COMPLETED
Conditions: Acute Coronary Syndrome|ST Elevation Myocardial Infarction|Percutaneous Coronary Intervention
Interventions: PROCEDURE: Percutaneous Coronary Intervention with or without manual aspiration thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of the Treovance Stent-Graft for Patients With Abdominal Aortic Aneurysms
Status: ACTIVE_NOT_RECRUITING
Conditions: Abdominal Aortic Aneurysm (AAA)
Interventions: DEVICE: Subjects who receive the Treovance stent-graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Amantadine Hydrochloride for Treatment of Severe Traumatic Brain Injury (TBI)
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Amantadine Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Test of a Cultural Intervention to Enhance Alaska Native Students' Behavioral Health
Status: COMPLETED
Conditions: Depression|Anxiety|Suicidal Ideation|Substance Use
Interventions: BEHAVIORAL: Knowing Who You Are (Becoming): Cultural Identity Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Safety and Tolerability Single Ascending Dose Study in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TC-2216
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Rectus Sheath Block Versus Intra-operative Rectus Sheath Block for Pediatric Umbilical Hernia Repair
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Pre-op percutaneous rectus sheath block|PROCEDURE: Intra-operative rectus sheath block|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Ustekinumab in Participants With Active Polymyositis and Dermatomyositis Who Have Not Adequately Responded to One or More Standard-of-care Treatments
Status: TERMINATED
Conditions: Polymyositis|Dermatomyositis
Interventions: DRUG: Ustekinumab 6 mg/kg|DRUG: Ustekinumab 90 mg|DRUG: Placebo IV|DRUG: Placebo SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The NOTICE Study: Neurosurgery and OrThopedIcs Communication Evaluation Study Following Lumbar Fusions
Status: RECRUITING
Conditions: Lumbar Spine Degeneration|Lumbar Spine Instability|Lumbar Spondylosis
Interventions: OTHER: Text Message Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Self-help Guided by Lay Providers for Anxiety in Older Adults
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: BEHAVIORAL: Self-help guided by a lay provider|BEHAVIORAL: Waiting list where participants wait for delayed treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome
Status: RECRUITING
Conditions: Genetic Disease|Chopra-Amiel-Gordon Syndrome|CAGS|ANKRD17
Interventions: OTHER: Observational Study|OTHER: Sample collection only
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Weekly Monitoring Strategy of Capillary INR Versus Monthly Monitoring Strategy of Venous INR in Elderly Patients in a Nursing Home.
Status: RECRUITING
Conditions: Atrial Fibrillation|Deep Vein Thrombosis|Stroke
Interventions: DEVICE: Weekly monitoring using the capillary International Normalised Ratio strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Pre-Operative Immuno-Modulatory SBRT (POIMS Trial): A Pilot Trial in Early Stage NSCLC
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: RADIATION: Non-ablative SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ORE - 30 Seconds (Oncologists Recommend Exercise in 30 Secs)
Status: RECRUITING
Conditions: Lung Cancer
Interventions: BEHAVIORAL: Exercise recommendation group|BEHAVIORAL: Exercise recommendation plus guidebook group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Role of Infected Blood Dendritic Cells in Heart Disease Risk
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Oral Antibiotic and Oral Rinse|PROCEDURE: Standard Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: A Pharmacokinetic Study of Ruxolitinib Phosphate Cream in Pediatric Subjects With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Ruxolitinib phosphate cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biofeedback for Psoriasis
Status: COMPLETED
Conditions: Psoriasis|Psoriasis Vulgaris|Psychophysiological Disorder|Anxiety|Depression|Psychological Stress|Physiological Stress|Quality of Life|Skin Disorder|Skin Diseases
Interventions: OTHER: HRV-Biofeedback/Mind-Body Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Flaxseed Compared With Placebo in Patients With Hypercholesterolemia
Status: COMPLETED
Conditions: Familial or Severe Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: flaxseed|DIETARY_SUPPLEMENT: whole wheat flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Determine The Percentage Of Depressed Outpatients Who Do Not Effectively Metabolize Extended-release Venlafaxine HCl
Status: COMPLETED
Conditions: Depression
Interventions: PROCEDURE: blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of the Oncolytic HSV1 MVR-C5252
Status: RECRUITING
Conditions: Recurrent High Grade Glioma
Interventions: BIOLOGICAL: MVR-C5252
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Analgesic Efficacy of Pericapsular Nerve Group (PENG) Block in Patients Undergoing Primary Total Hip Arthoplasty:
Status: RECRUITING
Conditions: Prospective|Randomized|Double-blind
Interventions: DRUG: Ropivacaine|OTHER: Physiological saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin and S-1 (OS) Versus Oxaliplatin and Capecitabine (XELOX) for Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasm
Interventions: DRUG: OS (oxalipaltin+S-1)|DRUG: XELOX (oxalipaltin+capecitabine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of BRAF and PIK3K Status on the Efficacy of 5-Fluorouracil/Leucovorin/Oxaliplatin (FOLFIRI) Plus Bevacizumab or Cetuximab in Patients With RAS Wild-type Metastatic Colorectal Carcinoma and < 3 Circulating Tumor Cells (CTC)
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: FOLFIRI + bevacizumab|DRUG: FOLFIRI + cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Melatonin on Postoperative Analgesia After Thoracotomy in Infants
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Melatonin 3 MG Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Low Pathogenicity Avian H10N7 Influenza Virus in a Healthy Human Challenge Model
Status: RECRUITING
Conditions: Influenza Infection
Interventions: BIOLOGICAL: A/Mallard/Ohio-99/MM4/1989 H10N7
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Azacytidine and Valproic Acid in Patients With Advanced Cancers
Status: COMPLETED
Conditions: Advanced Cancers
Interventions: DRUG: Azacitidine|DRUG: Valproic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Beta-glucan Enriched Oatcake Consumption on Metabolic Disease Risk Factors
Status: UNKNOWN
Conditions: Metabolic Syndrome X|Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Beta-glucan enriched oatcake|DIETARY_SUPPLEMENT: Isocaloric control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: New Clinical Applications for Internet-based Cognitive Behavior Therapy for Insomnia and Depression
Status: COMPLETED
Conditions: Insomnia|Major Depression|Minor Depression
Interventions: BEHAVIORAL: Therapist guided Internet-CBT for insomnia w. extra support|BEHAVIORAL: Therapist guided Internet-CBT for insomnia|BEHAVIORAL: Therapist guided Internet-CBT for insomnia and depression|BEHAVIORAL: Therapist Guided Internet-CBT for depression plus insomnia placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RW Effectiveness of Capmatinib in Advanced MET-dysregulated NSCLC Included in the French Compassionate Use Program (ATU)
Status: COMPLETED
Conditions: MET Alterations|Non Small Cell Lung Cancer|METex14 Mutations
Interventions: DRUG: Capmatinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: One-month Latent Tuberculosis Treatment for Renal Transplant Candidates
Status: RECRUITING
Conditions: Latent Tuberculosis|End Stage Renal Disease|Renal Transplant Candidate for Right Kidney|Renal Transplant Candidate for Left Kidney
Interventions: DRUG: 1 month Rifapentine, Isoniazid and Vitamin B6
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scaling up Evidence Based MNCH Interventions : A Quasi Experimental Study Umeed e Nau (UeN) Project
Status: UNKNOWN
Conditions: Maternal Complication of Pregnancy|Newborn Morbidity|Perinatal Problems
Interventions: OTHER: Improving of quality of care at health facility and outreach level
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Robotic Versus Electromagnetic Bronchoscopy for Pulmonary LesIon AssessmeNT: (the RELIANT Trial)
Status: COMPLETED
Conditions: Peripheral Pulmonary Lesions
Interventions: DEVICE: ILLUMISITE™ Platform (EMN bronchoscopy)|DEVICE: Ion™ Endoluminal System (SSCB bronchoscopy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of tACS Stimulation on Alpha Oscillations
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: XCSITE100 Stimulator tACS|DEVICE: XCSITE100 Stimulator Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Warfarin Prevents Portal Vein Thrombosis in Liver Cirrhotic Patients With Hypersplenism After Laparoscopic Splenectomy
Status: UNKNOWN
Conditions: Cirrhosis|Hypertension|Venous Thrombosis|Status; Splenectomy
Interventions: DRUG: Warfarin|DRUG: Dipyridamole|DRUG: Aspirin|DRUG: Low Molecular Weight Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Patupilone in Patients With Advanced Solid Tumors and Varying Degrees of Hepatic Function
Status: COMPLETED
Conditions: Advanced Malignancies|Tumors
Interventions: DRUG: Patupilone/EPO906
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Messaging Strategies to Increase Peer Education on COVID-19 Vaccination and Climate Change
Status: COMPLETED
Conditions: Vaccine Hesitancy|Climate Change
Interventions: BEHAVIORAL: Social diffusion intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: THIO Sequenced With Cemiplimab in Advanced NSCLC
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: 6-Thio-2'-Deoxyguanosine|DRUG: Cemiplimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of LY2216684 on Lorazepam
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: LY2216684|DRUG: Placebo|DRUG: Lorazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Hydrochloride and Carboplatin With or Without MK-0646 as First-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Lung Cancer
Interventions: BIOLOGICAL: dalotuzumab|DRUG: carboplatin|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy for Insomnia and Nocturnal Hot Flashes in Menopause
Status: COMPLETED
Conditions: Menopause|Insomnia|Hot Flashes
Interventions: BEHAVIORAL: CBT for Menopausal Insomnia (CBTMI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Prebent & Miniplates in Fixation of Lefort I Osteotomty in Maxillary Advancement.
Status: UNKNOWN
Conditions: Retruded Hypoplastic Maxilla
Interventions: PROCEDURE: lefort I osteotomy for maxillary advancement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sympathetic Denervation by Video-assisted Thoracoscopy in Control of Cardiac Arrhythmias in Patients With Chagas Disease
Status: RECRUITING
Conditions: Chagas Cardiomyopathy|Ventricular Arrythmia
Interventions: PROCEDURE: Bilateral sympathectomy|PROCEDURE: Catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Resolvins on the Resolve of Inflammatory Low Back Pain
Status: RECRUITING
Conditions: Low Back Pain|Inflammatory Response|Lumbar Disc Herniation
Interventions: DIETARY_SUPPLEMENT: Resolvin supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of Aflibercept on QTc Interval in Cancer Patients
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: aflibercept (AVE0005)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Intradialytic Exercise in Hemodiafiltration Patients
Status: COMPLETED
Conditions: End Stage Renal Disease|Hemodialysis|Sedentary Lifestyle
Interventions: BEHAVIORAL: Intradialytic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amotosalen-Ultraviolet A Pathogen-Inactivated Convalescent Plasma in Addition to Best Supportive Care and Antiviral Therapy on Clinical Deterioration in Adults Presenting With Moderate to Severe COVID-19
Status: COMPLETED
Conditions: Coronavirus Disease 2019 Infectious Disease (COVID-19 Infection)
Interventions: OTHER: convalescent plasma application to SARS-CoV-2 infected patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin Infusion vs. Spontaneous Follow-up for Third-stage of Labor After Second-trimester Abortion
Status: COMPLETED
Conditions: Abortion, Induced|Labor Stage, Third/Drug Effects|Pregnancy Trimester, Second|Oxytocin/Administration & Dosage
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LYmphadenectomy After NeoAdjuvant Chemotherapy
Status: UNKNOWN
Conditions: Advanced Ovarian Cancer (Stage III or IV) After Neoadjuvant Chemotherapy
Interventions: PROCEDURE: Systematic pelvic and aortic lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Entecavir Versus Lamivudine for Preventing the Risk of Hepatitis B Reactivation in NHL
Status: UNKNOWN
Conditions: Non-Hodgkin Lymphoma|Hepatitis B Reactivation
Interventions: DRUG: Entecavir|DRUG: Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Antiplatlet Effects of Standardized Tomato Extract in Hypertensive Subjects
Status: COMPLETED
Conditions: Hypertension,Essential|Obesity
Interventions: DRUG: acetylsalicylic acid|DRUG: Tomato Fruit Extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Acetaminophen-ibuprofen Combination on the Postoperative Pain After Laparoscopic Gynecology Surgery
Status: UNKNOWN
Conditions: Gynecologic Disease
Interventions: DRUG: Acetaminophen|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Trial to Look at the Safety and Effectiveness of Ustekinumab in Korean and Taiwanese Subjects With Moderate to Severe Plaque-type Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Placebo - Controlled Period (CP)|DRUG: Ustekinumab 45 mg - CP|DRUG: Placebo to ustekinumab 45 mg - after CP|DRUG: Ustekinumab 45 mg - after CP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mass Drug Administration of Dihydroartemisinin-piperaquine + Single Low-dose Primaquine to Accelerate Toward Elimination Activities
Status: COMPLETED
Conditions: Malaria,Falciparum|Malaria
Interventions: DRUG: Dihydroartemisinin-piperaquine|DRUG: Primaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION