pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety Study of Cyclosporine 0.010% to Treat Atopic Keratoconjunctivitis
Status: COMPLETED
Conditions: Atopic Conjunctivitis
Interventions: DRUG: Cyclosporine Vehicle|DRUG: Cyclosporine 0.010%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Decision Analysis Model for Prostate Cancer: A Randomized Trial
Status: TERMINATED
Conditions: Adenocarcinoma of Prostate|Adenocarcinoma of the Prostate Stage I|Adenocarcinoma of the Prostate Stage II|Adenocarcinoma of the Prostate Stage III
Interventions: BEHAVIORAL: Personalized Treatment Recommendations|BEHAVIORAL: Standard patient-physician counseling interaction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety and Efficacy of Domperidone in Pediatric Participants With Nausea and Vomiting Due to Acute Gastroenteritis
Status: TERMINATED
Conditions: Gastroenteritis
Interventions: OTHER: Oral Rehydration Therapy|DRUG: Domperidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Dynamics of Nebulized Dexmedetomidine
Status: UNKNOWN
Conditions: Abdominal Cancer
Interventions: DRUG: nebulized Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Isothiocyanates and Metabolic Health
Status: ACTIVE_NOT_RECRUITING
Conditions: Metabolic Disturbance
Interventions: DIETARY_SUPPLEMENT: Isothiocyanate rich sprouts|DIETARY_SUPPLEMENT: Placebo Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluate Safety and Pharmacokinetics of HLX70 in Healthy Adult Volunteers
Status: WITHDRAWN
Conditions: COVID-19
Interventions: DRUG: HLX70|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of the Use of Niaspan for Treatment of Dyslipidemia in Diabetic Nephropathy
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2|Kidney Failure, Chronic|Hyperlipidemia
Interventions: DRUG: Extended release niacin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Atomized Inhalation ICG for Treatment of Congenital Lung Malformations
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Sequestration|Congenital Pulmonary Airway Malformation|Indocyanine Green|Thoracoscopic Surgery|Children
Interventions: PROCEDURE: atomized inhalation ICG before thoracoscope pneumonectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Natural Killer Cells and INCB024360 for Recurrent Ovarian, Fallopian Tube, and Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Carcinoma|Primary Peritoneal Carcinoma
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|BIOLOGICAL: NK cells|BIOLOGICAL: IL-2|DRUG: INCB024360
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind, Comparison of the Efficacy and Safety of Amisulpride Versus Low-dose Amisulpride Plus Low-dose Sulpiride in the Treatment of Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: full-dose amisulpride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reproducibility of Nerve Fiber Layer Thickness Measurements in Patients With Glaucoma and Healthy Controls Using Spectral-Domain and Time-Domain OCT
Status: TERMINATED
Conditions: Glaucoma Patients and Healthy Controls
Interventions: DEVICE: Spectralis® SD-OCT, Heidelberg Engineering GmbH, H
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Patient-Controlled Epidural Analgesia After Uterine Artery Embolization
Status: UNKNOWN
Conditions: Uterine Artery Embolization for Uterine Leiomyomata
Interventions: PROCEDURE: Patient-controlled epidural analgesia|PROCEDURE: Continuous epidural analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Adaptive Interventions to Improve Posttraumatic Stress Disorder Treatment Outcomes in Federally Qualified Health Centers
Status: RECRUITING
Conditions: PTSD
Interventions: BEHAVIORAL: Prolonged Exposure for Primary Care (PE-PC)|BEHAVIORAL: Full Prolonged Exposure|BEHAVIORAL: Clinician Supported PTSD Coach App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BGB-15025 Alone and in Combination With Anti-PD-1 Monoclonal Antibody Tislelizumab in Participants With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: BGB-15025|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Anti-IgE Antibody Omalizumab on Patients With Chronic Sinusitis
Status: WITHDRAWN
Conditions: Chronic Sinusitis
Interventions: DRUG: Placebo|DRUG: Xolair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Transarterial Chemoinfusion (TAI) Combine Lenvatinib in Advanced Hepatocellular Carcinoma (HCC)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: COMBINATION_PRODUCT: TAI combine lenvatinib|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Safety of Anifrolumab in Adult Subjects With Active Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Active Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Anifrolumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy of Oral Molecular Hydrogen Supplement in Patients With Chronic Diseases
Status: RECRUITING
Conditions: Chronic Disease|Chronic Inflammation
Interventions: DIETARY_SUPPLEMENT: Hydrogen capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial Comparing Single Intra-op Dose of Methadone Versus Placebo in Patients Undergoing Spine Surgery
Status: COMPLETED
Conditions: Thoracolumbar Scoliosis
Interventions: DRUG: Methadone|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Changes in Bone Density With the Same Bone-health Plan, But With Different Bone-health Supplements
Status: COMPLETED
Conditions: Osteopenia
Interventions: DIETARY_SUPPLEMENT: AlgaeCal-1|DIETARY_SUPPLEMENT: AlgaeCal-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of a Prolonged Peripheral Nerve Block on the Level of Pain After a Knee Replacement
Status: NOT_YET_RECRUITING
Conditions: Knee Replacement Surgery
Interventions: DRUG: Continues peripheral block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult Anaplastic Astrocytoma|Adult Anaplastic Oligodendroglioma|Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Adult Mixed Glioma|Recurrent Adult Brain Neoplasm
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Temozolomide|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Longjohn Amgen Study - Effect of Denosumab...
Status: WITHDRAWN
Conditions: Arthroplasty, Replacement, Hip
Interventions: DRUG: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Comparing Concomitant Docetaxel + Gemcitabine to Sequential Therapy of Docetaxel Followed by Gemcitabine
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: Gemcitabine, Docetaxel|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Tolerability of Mucinex™(Guaifenesin) 600 mg Extended-Release Bi-Layer Tablets in the Treatment of Otherwise Healthy Patients With Symptoms of Cough, Thickened Mucus and Chest Congestion
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Mucinex™ extended-release (SE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pilot, Open-Label, Phase II, Randomized Study to Determine the Effects of Viracept on the Outcome of Cutaneous and Mucosal KS in AIDS Patients With CD4 <= 500 Cells/mm3
Status: COMPLETED
Conditions: Sarcoma, Kaposi|HIV Infections
Interventions: DRUG: Nelfinavir mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of Dalotuzumab (MK-0646) in Breast Cancer Patients (MK-0646-013)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: dalotuzumab (MK0646)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blinatumomab Followed by High-dose Chemotherapy for Ph-negative Acute Lymphoblastic Leukemia (ALL)
Status: COMPLETED
Conditions: Lymphoblastic Leukemia, Acute, Adult|Ph Negative ALL|Newly Diagnosed
Interventions: DRUG: Blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of BBC1501 Intravitreal Injection in Patients With Neovascular Age-Related Macular Degeneration (nAMD)
Status: NOT_YET_RECRUITING
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: BBC1501
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain and Comfort During Endotracheal Suction in Premature Neonates
Status: COMPLETED
Conditions: Premature
Interventions: OTHER: Swaddling|OTHER: Oropharyngeal colostrum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hip Fracture Surgery and Oral Nutritional Supplements
Status: TERMINATED
Conditions: Hip Fracture
Interventions: DIETARY_SUPPLEMENT: Oral nutritional Supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Inetetamab Plus Cyclophosphamide Metronomic Chemotherapy Plus Aromatase Inhibitor in Metastatic HER2+/HR+ Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Inetetamab Plus Cyclophosphamide Metronomic Chemotherapy Plus AI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carvedilol SR Study for Biomarkers From Blood and Urine and Safety of in Patients With Heart Failure With Preserved Ejection Fraction
Status: UNKNOWN
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: Carvedilol SR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Ultrasound for Early Identification of Patients at Risk of Swallowing Disorders Acquired in the ICU
Status: RECRUITING
Conditions: Patient Under Mechanical Ventilation
Interventions: OTHER: Ultrasound|OTHER: nasofibroscopie
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Flavopiridol and Imatinib Mesylate in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: alvocidib|DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Ticagrelor and Clopidogrel Pharmacodynamics After Thrombolysis
Status: WITHDRAWN
Conditions: Acute ST Segment Elevation Myocardial Infarction|Acute Coronary Syndrome
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Hyperbaric Oxygen Therapy in Acute Ischemic Stroke Ischemic Stroke Recovery (Pro00061930)
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DEVICE: Hyperbaric Oxygen Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the XACT Robotic System for Image-guided Percutaneous Lung Procedures
Status: WITHDRAWN
Conditions: CT-guided Minimally Invasive Procedures e.g. Biopsies
Interventions: DEVICE: XACT Robotic System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Lifting Capacity of Fillers
Status: UNKNOWN
Conditions: Esthetic & Topographic Shifts From Facial Fillers
Interventions: DEVICE: injection of Restylane Lyft and Restylane L
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Polyglucosamine for Weight Loss
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: DEVICE: Polyglucosamine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Seropersistence of TBE Antibodies and the Booster Response to FSME-IMMUN 0.5 ml in Adults Aged 18 - 67 Years
Status: COMPLETED
Conditions: Tick-borne Encephalitis
Interventions: BIOLOGICAL: FSME-IMMUN 0.5ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Remimazolam in the Extraction of Impacted Wisdom Teeth
Status: UNKNOWN
Conditions: Dental Anxiety|Sedation Complication|Anterograde Amnesia
Interventions: DRUG: Remimazolam besylate|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Human Leukocyte Antigen-A*02:01-restricted Tumor Vessel Specific Peptide Vaccination for Advanced Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer|Pancreas Neoplasms
Interventions: BIOLOGICAL: HLA-A*02:01-restricted VEGFR1-derived peptide vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Muscle Activity in Unilateral Posterior Crossbite
Status: UNKNOWN
Conditions: Malocclusion|Muscle Activity|Maxillary Expansion
Interventions: OTHER: Rapid Maxillary Expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Speech-in-Noise Treatments for Hypophonia in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease|Speech Disorders
Interventions: BEHAVIORAL: Speech-in-Noise Treatment Program|BEHAVIORAL: Speech-to-Noise Feedback Device Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can PRP Reduce Pro-Inflammatory Biomarkers Following ACL Injury
Status: WITHDRAWN
Conditions: ACL - Anterior Cruciate Ligament Rupture|ACL Injury
Interventions: BIOLOGICAL: Platelet Rich Plasma|OTHER: Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I - Escalating Dose Study of siG12D LODER (Local Drug EluteR) in Patients With Locally Advanced Adenocarcinoma of the Pancreas, and a Single Dose Study of siG12D LODER (Local Drug EluteR) in Patients With Non-operable Adenocarcinoma of the Pancreas
Status: COMPLETED
Conditions: Pancreatic Ductal Adenocarcinoma|Pancreatic Cancer
Interventions: DRUG: siG12D LODER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autotitrating Versus Standard Non-invasive Ventilation (NIV) in Newly Diagnosed Patients
Status: COMPLETED
Conditions: Nocturnal Hypoventilation|Neuromuscular Disease|Chest Wall Disorder
Interventions: DEVICE: AutoVPAP|DEVICE: VPAPIIIST-A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of GR1501 in Patients With Radiographic Axial Spondyloarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Axial Spondyloarthritis
Interventions: BIOLOGICAL: GR1501 low dose|BIOLOGICAL: GR1501 high dose|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of Glaucoma Implant in Primary Open Angle Glaucoma
Status: NOT_YET_RECRUITING
Conditions: Glaucoma
Interventions: DEVICE: GELA|DEVICE: XEN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Microglial Activation Positron Emission Tomography (PET) Brain Imaging in Multiple Sclerosis and Alzheimer's Disease
Status: UNKNOWN
Conditions: Multiple Sclerosis|Alzheimer's Disease
Interventions: DRUG: [F-18]PBR06|DRUG: [C-11]PBR28
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comfort Comparison of Intravitreal Injection Eyelid Retraction Techniques
Status: COMPLETED
Conditions: Intravitreal Injection|Pain
Interventions: OTHER: Visual analog scale (VAS) of pain to evaluate the discomfort participants experience.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Microvascular and Metabolic Effects of High-intensity Interval Exercise Training
Status: WITHDRAWN
Conditions: Obesity|Overweight|Physical Activity
Interventions: BEHAVIORAL: High-intensity interval exercise training in the fed state|BEHAVIORAL: Continous exercise training in the fed state|BEHAVIORAL: High-intensity interval exercise training in the fasting state|BEHAVIORAL: Continous exercise training in the fasting state
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Neoadjuvant Radiochemotherapy in Adenocarcinoma of the Gastric-oesophageal Junction
Status: COMPLETED
Conditions: Esophageal Neoplasms|Stomach Neoplasms
Interventions: DRUG: Docetaxel, Oxaliplatin|PROCEDURE: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC
Status: NOT_YET_RECRUITING
Conditions: Metastatic Colorectal Cancer|Hepatocellular Carcinoma
Interventions: DRUG: Enfortumab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of VX-770 in Subjects With Moderate Hepatic Impairment and in Matched Healthy Subjects
Status: COMPLETED
Conditions: In Development for Cystic Fibrosis
Interventions: DRUG: VX-770
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Depersonalization Disorder With Repetitive Transcranial Magnetic Stimulation (rTMS)
Status: WITHDRAWN
Conditions: Depersonalization Disorder
Interventions: DEVICE: Daily rTMS with Active coil|DEVICE: Daily rTMS with Sham coil|DEVICE: Open Label Daily rTMS with Active coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase IV, Open-label, Randomised, Pilot Clinical Trial Designed to Evaluate the Potential Neurotoxicity of Dolutegravir/Lamivudine/Abacavir in Neurosymptomatic HIV Patients and Its Reversibility After Switching to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide. DREAM Study
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: ELV/COBI/FTC/TAF|DRUG: DTG/3TC/ABC + ELV/COBI/FTC/TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Art Therapy for Caregivers of Young Patients Undergoing Bone Marrow Transplant for Cancer
Status: COMPLETED
Conditions: Health Status Unknown|Psychosocial Effects of Cancer and Its Treatment
Interventions: OTHER: psychosocial support for caregiver|OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment|PROCEDURE: stress management therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Duct-to-duct vs Roux-en-y Hepaticojejunostomy for Biliary Reconstruction in Adult Living Donor Liver Transplantation
Status: UNKNOWN
Conditions: Liver Transplantation
Interventions: PROCEDURE: surgical technique: duct-to-duct biliary reconstruction|PROCEDURE: surgical technique: roux-en-y biliary reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vestibular Socket Therapy With Simultaneous Implant Placement Versus Contour Augmentation With Early Implant Placement
Status: UNKNOWN
Conditions: Loss of Teeth Due to Extraction
Interventions: PROCEDURE: immediate implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess Safety and Efficacy of Autologous Cultured Epidermal Grafts Containing Epidermal Stem Cells Genetically Modified in Patients With RDEB.
Status: TERMINATED
Conditions: Recessive Dystrophic Epidermolysis Bullosa
Interventions: DRUG: Genetically corrected cultured epidermal autograft (ATMP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Early Sleep After Action Observation and Motor Imagery After Metacarpal Fracture Surgery
Status: NOT_YET_RECRUITING
Conditions: Hand Injuries|Action Observation|Motor Imagery
Interventions: BEHAVIORAL: Action observation plus motor imagery followed by sleep|BEHAVIORAL: Action observation plus motor imagery|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Trial of BAT4406F Injection in Patients With Neuromyelitis Optica Spectrum Disorders
Status: RECRUITING
Conditions: Neuromyelitis Optica Spectrum Disorders
Interventions: DRUG: BAT4406F
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of HF10 in Patients With Refractory Head and Neck Cancer or Solid Tumors With Cutaneous and/or Superficial Lesions
Status: COMPLETED
Conditions: Refractory Head and Neck Cancer|Squamous Cell Carcinoma, Skin|Carcinoma of the Breast|Malignant Melanoma
Interventions: DRUG: HF10
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Recovery After Reverse Shoulder Arthroplasty With a Personalized Mobile Health Application
Status: NOT_YET_RECRUITING
Conditions: Shoulder Osteoarthritis
Interventions: OTHER: interactive mHealth application for patients undergoing RSA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindful Self-Compassion to Assist Emerging Adults With Diabetes Transition to Adulthood
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1
Interventions: BEHAVIORAL: Mindful Self-Compassion (MSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessing Adherence to Home Telemedicine in Individuals With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: Go Home tablet with linked GoSpiro and 3230 Pulse Oximeter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of DHA on Proinflammatory Cytokines Including Platelets Activating Factor (PAF) in Preterm Neonates
Status: COMPLETED
Conditions: Neonatal Disease
Interventions: DIETARY_SUPPLEMENT: DHA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy and Safety of Elritercept in Adult Participants With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) With Anemia (RENEW)
Status: NOT_YET_RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: BIOLOGICAL: KER-050|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reamer Irrigator Aspirator (RIA) vs Autogenous Iliac Crest Bone Graft (AICBG) for the Treatment of Non-unions
Status: UNKNOWN
Conditions: Nonunion of Bone Graft|Fractures Non Union
Interventions: OTHER: RIA harvesting group|OTHER: AICBG harvesting group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantitative COVID-19 SARS-CoV-2 Antibody Pre and Post Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Laboratory Assessment SARS-CoV-2 Antibody Levels Before and After Surgery for Patients Requiring Cardiopulmonary Bypass
Interventions: DIAGNOSTIC_TEST: SARS-CoV-2 Antibody test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nivolumab, Cabozantinib S-Malate, and Ipilimumab in Treating Patients With Recurrent Stage IV Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Metastatic Lung Non-Squamous Non-Small Cell Carcinoma|Recurrent Lung Non-Squamous Non-Small Cell Carcinoma|Stage IV Lung Non-Small Cell Cancer AJCC v7
Interventions: DRUG: Cabozantinib|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucose Response to a Formula for Patients at Risk of Hypoglycaemia
Status: COMPLETED
Conditions: Postprandial Hypoglycemia
Interventions: DIETARY_SUPPLEMENT: First concept product (containing 50 grams of carbohydrates)|DIETARY_SUPPLEMENT: Second concept product (containing 50 grams of carbohydrates)|DIETARY_SUPPLEMENT: Reference product (containing 50 grams of carbohydrates)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Medical Ozone Therapy in Patients With Chronic Hepatitis B
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DEVICE: medical ozone therapy with tianyi|DEVICE: medical ozone therapy with humares|DRUG: Diammonium glycyrrhizinate Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on Safety and Preliminary Efficacy of ALA in Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: ALA 2.5%|DRUG: ALA 5%|DRUG: ALA 10%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Immunogenicity of VAL-506440 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: VAL-506440|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy and Safety of Pyrotinib, Trastuzumab Combined With Taxanes in the Treatment of Trastuzumab-treated HER2+ Advanced Breast Cancer (ABC).
Status: RECRUITING
Conditions: HER2-positive Breast Cancer|Advanced Breast Cancer
Interventions: DRUG: Pyrotinib|DRUG: Trastuzumab|DRUG: Taxanes|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Milk Oligosaccharides (HMOs) for Irritable Bowel Syndrome (IBS)
Status: TERMINATED
Conditions: Irritable Bowel Syndrome|IBS - Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Human Milk Oligosaccharide Mix|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of a Plant Protein Diet to a Animal Protein Diet Emphasized in Type 2 Diabetics
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Nutrition Disorders|Obesity|Body Weight|Metabolic Syndrome x|Metabolic Diseases
Interventions: OTHER: High animal protein diet group|OTHER: High plant protein diet group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Early and Active Nutritional and Dietary Management grade3 or More Toxicities Induced by Chemotherapy and Targeted Therapies Administered to Patients as First Intention for Non Surgical Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: OTHER: Early and active nutritional support.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Nolasiban to Increase Pregnancy Rates in Women Undergoing IVF
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Nolasiban|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of IBI306 in Chinese Subjects With Non-familial Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: IBI306 450mg SC Q4W|DRUG: Placebo SC Q4W|DRUG: IBI306 600mg SC Q6W|OTHER: Placebo SC Q6W
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CellFX ® Percutaneous Electrode (PE) Treatment of Benign Thyroid Nodules
Status: RECRUITING
Conditions: Thyroid Nodule (Benign)
Interventions: DEVICE: CellFX® Percutaneous Electrode (PE) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Rehabilitation Outcome of Patients With Lumbar Spondylolisthesis. A Prospective Randomized Study
Status: UNKNOWN
Conditions: Spinal Instability
Interventions: DEVICE: Biodex balance training|OTHER: Rehabilitation including core spinal stabilization exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Supraglottic and Oropharyngeal Decontamination on the Incidence of Ventilator-associated Pneumonia
Status: COMPLETED
Conditions: Trauma Injury|Brain Injuries|Abdominal Sepsis|Pancreatitis|Meningitis|Encephalitis|Seizures|Acute Respiratory Distress Syndrome
Interventions: DRUG: Control|DRUG: Antiseptic Solution|DRUG: Bacteriophage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Shockwave, Photobiomodulation, and Physical Therapy for Achilles Tendinopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Achilles Tendinopathy
Interventions: OTHER: Physical Therapy|DEVICE: Shockwave Therapy|DEVICE: Photobiomodulation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intracoronary Administration of Levosimendan in Cardiac Surgery Patients
Status: TERMINATED
Conditions: Myocardial Stunning
Interventions: DRUG: levosimendan|DRUG: Vitamin B 12
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluorouracil and Leucovorin With or Without Irinotecan in Treating Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFIRI regimen|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study in Hepatitis C Virus (HCV) Infected Patients Undergoing Liver Transplantation to Evaluate a Human Monoclonal Antibody Against Hepatitis C
Status: TERMINATED
Conditions: HCV Infection|Liver Transplantation
Interventions: BIOLOGICAL: MBL-HCV1|OTHER: 0.9% Sodium chloride Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessing the Safety/Efficacy of Asacol® Given Every 12 Hours to Children and Adolescents for the Maintenance of Remission of Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: Asacol 400 mg|DRUG: Asacol 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Approach Bias Modification in Heavy Drinking Veterans With Mild to Moderate Traumatic Brain Injury
Status: WITHDRAWN
Conditions: Alcohol Use Disorder|Mild-Moderate Traumatic Brain Injury
Interventions: BEHAVIORAL: Personalized VR Alcohol Approach Bias Modification (ApBM) Condition|BEHAVIORAL: Sham Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TQC3927 Powder for Inhalation in Healthy Adult Subjects
Status: NOT_YET_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: TQC3927 powder for inhalation|DRUG: TQC3927 powder for inhalation placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Intensity Functional Training for Individuals With Neurologic Diagnoses and Their Care Partners
Status: RECRUITING
Conditions: Neurologic Disorder|Parkinson Disease|Spinal Cord Injuries|Spina Bifida|Stroke|Poliomyelitis|Multiple Sclerosis|Brain Injuries
Interventions: BEHAVIORAL: HIFT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 5FU vs 5FU With Viscoelastic Formulation for the Prevention of Scarring Post-trabeculectomy
Status: COMPLETED
Conditions: Glaucoma|Trabeculectomy|Wound Healing
Interventions: DRUG: 5 Fluorouracil with hyaluronic acid|DRUG: 5 Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Itacitinib (INCB039110) in Combination With Ibrutinib in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: itacitinib|DRUG: ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anxiety, Pain, and Satisfaction Related to First Vaginal Examination in Women
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Pain|Satisfaction
Interventions: PROCEDURE: Intervention group I|PROCEDURE: Intervention group II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of BL-M02D1 in Patients With Locally Advanced or Metastatic Triple Negative Breast Cancer or Other Solid Tumors
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: BL-M02D1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Chemo and Chemoradiotherapy for Adenocarcinoma of the Stomach and Gastroesophageal Junction (GEJ)
Status: COMPLETED
Conditions: Stomach Cancer|Gastric Cancer
Interventions: DRUG: 5-Fluorouracil|DRUG: Folinic Acid|DRUG: Oxaliplatin|RADIATION: Radiotherapy|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Montreal Museum of Fine Arts Visits and Older Community Dwellers With a Precarious State
Status: COMPLETED
Conditions: Well Aging|Health Impairment|Social Isolation|Old Age
Interventions: OTHER: Guided tour at the Montreal Museum of Fine Arts
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Understanding the Effects of Transcutaneous Auricular Neurostimulation for Treatment of Chronic Pain
Status: RECRUITING
Conditions: Opioid Withdrawal|Analgesia
Interventions: DEVICE: transcutaneous Auricular neurostimulation - Active|DEVICE: transcutaneous auricular neurostimulation - Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictors of Treatment Response to Fluoxetine in PTSD Following a Recent History of War Zone Stress Exposure
Status: UNKNOWN
Conditions: Posttraumatic Stress Disorder, Combat-related
Interventions: DRUG: Fluoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dynamic Balance Exercises on Balance in Patients With Ankylosing Spondylitis.
Status: NOT_YET_RECRUITING
Conditions: Ankylosing Spondylitis
Interventions: PROCEDURE: Dynamic balance exercise with tecnobody prokin 252 balance device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mirvetuximab Soravtansine (MIRV) With Carboplatin in Second-line Treatment of Folate Receptor Alpha (FRα) Expressing, Platinum-sensitive Epithelial Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: High Grade Ovarian Cancer|Primary Peritoneal Cancer|Fallopian Tube Cancer
Interventions: DRUG: Mirvetuximab soravtansine|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Dose-Finding Study of DTX401 (AAV8G6PC) in Adults With Glycogen Storage Disease Type Ia (GSDIa)
Status: COMPLETED
Conditions: GSD1
Interventions: GENETIC: DTX401|DRUG: steroid regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Pharmacodynamic Effects of Escitalopram Depending on Genetic Polymorphisms of the ABCB1-gene
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Camrelizumab Combined With Apatinib Mesylate or Camrelizumab Alone for First-line Treatment in Subjects With Programmed Death Ligand 1 (PD-L1) Positive Relapsed or Advanced Non-small Cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: PD-L1 Positive Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Camrelizumab 200mg|DRUG: Apatinib Mesylate 250mg|DRUG: Pemetrexed disodium for injection|DRUG: Paclitaxel injection|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor, Adult|Non-small Cell Lung Cancer|Melanoma
Interventions: DRUG: KIN-2787|DRUG: KIN-2787 and binimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Hematopoietic Stem Cell Transplantation in Pancreatic Adenocarcinoma
Status: TERMINATED
Conditions: Pancreatic Adenocarcinoma
Interventions: PROCEDURE: Allogeneic hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of Cockroach Immunotherapy by the Inner-City Asthma Consortium
Status: COMPLETED
Conditions: Asthma|Perennial Allergic Rhinitis
Interventions: BIOLOGICAL: German cockroach (Blattella germanica) allergenic extract
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tenofovir Abacavir Platelet Activation Study
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: abacavir (600 mg QD)|DRUG: tenofovir (245 mg QD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Flavocoxid 500 mg Compared With Naproxen 500 mg in Subjects With Moderate-severe Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of Knee
Interventions: DIETARY_SUPPLEMENT: flavocoxid|DRUG: Naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Sahasthara ME vs Diclofenac ME for Treating Primary Knee Osteoarthritis
Status: COMPLETED
Conditions: Primary Knee Osteoarthritis
Interventions: DRUG: Sahasthara Microemulsion|DRUG: Diclofenac Microemulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Mogamulizumab With DA-EPOCH in Patients With Aggressive T Cell Lymphoma
Status: NOT_YET_RECRUITING
Conditions: T Cell Lymphoma
Interventions: DRUG: Mogamulizumab|DRUG: DA-EPOCH Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy of Vagitocin in Postmenopausal Women With Vulvovaginal Atrophy Symptoms
Status: COMPLETED
Conditions: Vulvovaginal Atrophy
Interventions: DRUG: Oxytocin 400 IU vaginal gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Oxaliplatin, Irinotecan, and S-1 in Gastric Cancer
Status: COMPLETED
Conditions: Stomach Neoplasm
Interventions: DRUG: Oxaliplatin, Irinotecan, S-1(OIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of a Non-invasive Neuromodulation Device on Urgency Urinary Incontinence in Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DEVICE: (VERV™ System)|DEVICE: Sham version of (VERV™ System)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT