pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Lonafarnib and Temozolomide in Treating Patients With Glioblastoma Multiforme That Is Recurrent or Did Not Respond to Previous Treatment With Temozolomide
Status: UNKNOWN
Conditions: Malignant Supratentorial Neoplasm|Recurrent Glioblastoma|Recurrent Gliosarcoma
Interventions: DRUG: Lonafarnib|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictive Factors for Treatment Response in Patients With Newly-diagnosed Polymyalgia Rheumatica and Giant Cell Arteritis
Status: UNKNOWN
Conditions: Polymyalgia Rheumatica (PMR)|Giant Cell Arteritis (GCA)
Interventions: OTHER: Data collection for cellular analyses (Immune subset composition, GCR expression, in vitro steroid responsiveness)|OTHER: Data collection for exploratory analyses of endogenous steroid hormones|OTHER: Data collection for correlation between clinical defined and lab defined GC responsivness|OTHER: Data collection for Prednisone metabolism
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Sensory Integration Training on Balance and Confidence in Patients With Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: OTHER: Sensory integration training|OTHER: Routine physical therapy|OTHER: General coordination exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: pBFS-guided Noninvasive Neuromodulation for Pre-school Children With ASD
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: active iTBS|DEVICE: active iTBS|DEVICE: sham iTBS|DEVICE: sham iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chinese Medicine(Hu Yang Yang Kun Formula) for Primary Ovarian Insufficiency
Status: COMPLETED
Conditions: Primary Ovarian Insufficiency
Interventions: OTHER: Chinese medicine granules (HuYang Yang Kun Formula)|DIETARY_SUPPLEMENT: dehydroepiandrosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study on Postmenopausal Women With Early Stage Breast Cancer: WBI Versus APBI
Status: TERMINATED
Conditions: Cancer of Breast
Interventions: RADIATION: Hypofractionated WBI|RADIATION: Accelerated Partial Breast Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Transcranial Photobiomodulation to Improve Cognition and Self-Reported Outcomes in Survivors of Childhood Cancer
Status: RECRUITING
Conditions: ALL|Hodgkin Lymphoma|Cancer|Survivorship
Interventions: DEVICE: Transcranial photobiomodulation (tPBM) - Mobile System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: The Renal Safety of Tenofovir Alafenamide in HBV-related Acute-on-chronic Liver Failure: Real-World Study
Status: COMPLETED
Conditions: Antiviral Drugs
Interventions: DRUG: tenofovir alafenamide|DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ED90 of Norepinephrine and Phenylephrine Infusions Under Intensive Treatment
Status: NOT_YET_RECRUITING
Conditions: Adverse Effect
Interventions: DRUG: Norepinephrine|DRUG: Phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Whole Body Unloading on Physiological Function
Status: COMPLETED
Conditions: Muscle Atrophy|Weightlessness|Sleep Disturbance|Astronaut-Bone Demineralisation Syndrome
Interventions: OTHER: HBF Bed Rest
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Dexmedetomidine, Melatonin and Pregabalin
Status: NOT_YET_RECRUITING
Conditions: Endoscopic Sinus Surgery
Interventions: DRUG: Dexmedetomidine|DRUG: Melatonin|DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Determining Optimal Treatment Sequences in Anxious Depression (DOTS-AD)
Status: RECRUITING
Conditions: Anxious Depression|Depression
Interventions: DRUG: Escitalopram|DRUG: Duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Functional Recovery Between Early- and Late Bisphosphonate Treatment Following Hemiarthroplasty
Status: UNKNOWN
Conditions: Osteoporotic Fractures|Femoral Neck Fracture
Interventions: DRUG: Risedronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Superiority of Omega-3 Versus Placebo on the Improvement of ADHD in Children
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: DIETARY_SUPPLEMENT: Omega-3 Fatty Acids|DIETARY_SUPPLEMENT: Medium Chain Triglycerides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Favipiravir From Flupirava 200 mg Tablet (European Egyptian Pharmaceutical Industries , Egypt) Versus Avigan 200 mg Tablets (Man. by Toyama Chemical Co., Ltd Japan)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Flupirava|DRUG: Avigan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of a New Botulinum Toxin Type A for Treatment of Facial Expression Lines
Status: COMPLETED
Conditions: Wrinkles
Interventions: DRUG: Botulift|DRUG: Botox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Acute Effect of a Walnut Intervention on Cognitive Performance, Brain Activation, and Serum Markers of Inflammation in Young Adults
Status: COMPLETED
Conditions: Cognitive Change|Mood|Inflammatory Response|Brain Derived Neurotrophic Factor Level|Satiety
Interventions: OTHER: Control|OTHER: 50 g Walnut
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nab-Paclitaxel Versus Paclitaxel Plus Carboplatin in Advanced Squamous Cell Non Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: nab-paclitaxel|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Pharmacodynamics of Doripenem Between 4-hour and 1-hour Infusion in Patients With Ventilator-associated Pneumonia
Status: COMPLETED
Conditions: Ventilator-Associated Pneumonia
Interventions: DRUG: Doripenem|DRUG: Doripenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Camelina Sativa Oil in Free-living Older Adults
Status: COMPLETED
Conditions: Inflammation|Malnutrition|Hyperglycemia|Dyslipidemias
Interventions: OTHER: Novel food snack|OTHER: Placebo snack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: After Discharge Management of Low Income Frail Elderly
Status: COMPLETED
Conditions: Heart Failure, Congestive|Coronary Arteriosclerosis|Atrial Fibrillation|Cerebrovascular Accident|Pulmonary Disease, Chronic Obstructive|Diabetes Mellitus|Hypertension|Osteoarthritis|Osteoporosis
Interventions: BEHAVIORAL: Behavioral|BEHAVIORAL: behavioral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Euploid Rate of Blastocyst Derived From PPOS VS Antagonist Protocol
Status: COMPLETED
Conditions: IVF
Interventions: PROCEDURE: Gonadotrophin releasing hormone antagonist protocol|PROCEDURE: Progestin-primed ovarian stimulation protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Expanding Access to Care Through Telemedical Support for Vital Sign Monitoring in High-risk Patients With Cancer
Status: RECRUITING
Conditions: Hypertension
Interventions: DEVICE: Cellular enabled blood pressure cuff|DEVICE: Standard of Care Cuff
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DEC-205/NY-ESO-1 Fusion Protein CDX-1401and Decitabine in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Alkylating Agent-Related Acute Myeloid Leukemia|Chronic Myelomonocytic Leukemia|Myelodysplastic Syndrome|Refractory Anemia With Excess Blasts in Transformation
Interventions: BIOLOGICAL: DEC-205/NY-ESO-1 Fusion Protein CDX-1401|DRUG: Decitabine|OTHER: Laboratory Biomarker Analysis|DRUG: Poly ICLC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing Access to Colorectal Cancer Testing (IACCT) for Blacks
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Carcinoma
Interventions: OTHER: Fecal Immunochemical Test (FIT) Kit|BEHAVIORAL: Culturally targeted Photo Novella Booklet|BEHAVIORAL: Screen for Life Brochure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study to Evaluate the Efficacy and Safety of BBP-418 (Ribitol) in Patients With Limb Girdle Muscular Dystrophy 2I (LGMD2I)
Status: RECRUITING
Conditions: Limb-Girdle Muscular Dystrophy Type 2I (LGMD2I)
Interventions: DRUG: BBP-418 (ribitol)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Evaluating the Safety and Clinical Activity of Radioiodide (131I-) as a Novel Targeted Therapy for Metastatic Breast Cancer That Overexpresses Functional Na/I Symporter
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: RADIATION: Radioiodide (131I-)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the TAXUS Liberté Stent for the Treatment of de Novo Coronary Artery Lesions in Small Vessels
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: TAXUS Liberté-SR|DEVICE: TAXUS™ Express2|DEVICE: Express2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anesthesia and Cancer Study: Renal Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Propofol|DRUG: Inhaled General Anesthetics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A 12 Week Study To Assess Efficacy And Safety Of GW856553 In Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GW856553|DRUG: Placebo|DRUG: Seretide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Losartan and Nivolumab in Combination With FOLFIRINOX and SBRT in Localized Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: FOLFIRINOX|DRUG: Losartan|DRUG: Nivolumab|RADIATION: SBRT|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Practice Guidelines and Impact of Audit and Feedback in the Emergency Department
Status: COMPLETED
Conditions: Shock, Septic|Community Acquired Pneumonia
Interventions: BEHAVIORAL: Feedback with Peer Comparison
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Time to Post-Anesthesia Neurological Evaluation With Three Different Anesthetic Techniques
Status: COMPLETED
Conditions: Carotid Artery Stenosis
Interventions: DRUG: Remifentanil, Propofol, and Desflurane|DRUG: Remifentanil, Dexmedetomidine, and Desflurane|DRUG: Remifentanil and Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Viral Kinetics, Interferon Stimulated Genes (ISGs) and mirRNA Among Subjects Infected With Different Hepatitis C Virus Genotypes During Therapy With Sofosbuvir and GS-5816
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Sofosbuvir|DRUG: GS-5816
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study on Cesarean Wound Outcomes
Status: COMPLETED
Conditions: Surgical Site Infection|Cosmetic Appearance of Cesarean Scar|Post Operative Pain
Interventions: DEVICE: Silver-impregnated dressing|DEVICE: Telfa pad dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Partnered Multicomponent Exercise for Elderly in Long-term Care Facilities
Status: COMPLETED
Conditions: Exercise|Long Term Care Facilities|Physical Function|Happiness
Interventions: OTHER: partnered multicomponent exercises program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Repositioning Frequency Neonates Receiving Phototherapy
Status: COMPLETED
Conditions: Bilirubinemia|Newborn Jaundice
Interventions: BEHAVIORAL: Supine position group|BEHAVIORAL: Hourly position change group|BEHAVIORAL: Control Group (2-hour position change)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Chronic Itch in Atopic Dermatitis (Eczema): Nerve Function
Status: COMPLETED
Conditions: Cutaneous Nerves CNS Itch
Interventions: DRUG: Clonidine|DRUG: Naltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tralokinumab Monotherapy for Moderate to Severe Atopic Dermatitis - ECZTRA 1 (ECZema TRAlokinumab Trial no. 1)
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Tralokinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Abatacept in Japanese Patients With Active Rheumatoid Arthritis While Receiving Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Abatacept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Humanized Anti-GD2 Antibody Hu3F8 and Allogeneic Natural Killer Cells for High-Risk Neuroblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroblastoma|High-Risk
Interventions: DRUG: cyclophosphamide|BIOLOGICAL: NK cells|BIOLOGICAL: hu3F8|DRUG: rIL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outpatient Discharge Therapy With Saxagliptin+MetforminXR vs GlipizideXL for Type 2 Diabetes With Severe Hyperglycemia
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2|Hyperglycemia
Interventions: DRUG: Glipizide XL|DRUG: Saxagliptin + Metformin XR|DRUG: Metformin XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metoprolol and Formoterol in Chronic Obstructive Pulmonary Disease (COPD)
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Metoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Announcement of Rare Metabolic Diseases in Systematic Newborn Screening: the Phenylketonuria Experience.
Status: NOT_YET_RECRUITING
Conditions: Phenylketonuria
Interventions: BEHAVIORAL: socio-psychological questionnaire|BEHAVIORAL: revised event impact scale (IER-S)|OTHER: Non directive interview|OTHER: Stern interview|OTHER: semi-directive interview
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Arsenic Trioxide and Imatinib Mesylate in Treating Patients With Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: arsenic trioxide|DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Characterize the Pharmacokinetics of DA-8031 in Healthy Male Subjects
Status: COMPLETED
Conditions: Premature Ejaculatory Dysfunction
Interventions: DRUG: DA-8031|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy of Maintenance Treatment With Capecitabine Plus Apatinib in Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Apatinib+Capecitabine|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Naval Medical Center San Diego (NMCSD) - Ambulatory Continuous Peripheral Nerve Blocks for Treatment of Post-Amputation Phantom Limb and Stump Pain
Status: TERMINATED
Conditions: Amputation|Phantom Limb|Stump Pain
Interventions: DRUG: perineural ropivacaine|DRUG: normal saline (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Efficacy and Safety of Ziprasidone and Aripiprazole for the Treatment fo Schizophrenia or Schizoaffective Disorder in Hospitalized Patients
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole|DRUG: Ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Retrograde Cholangiopancreatography In Patients Older Than 65Years Old With Obstructive Jaundice: Efficacy And Outcome
Status: NOT_YET_RECRUITING
Conditions: Obstructive Jaundice
Interventions: PROCEDURE: Endoscopic retrograde cholangiopancreatography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Impact of Physiotherapy on Spasticity, Upper Limb Function, Daily Activities, and Kinesiophobia in Hemiplegic Patients
Status: COMPLETED
Conditions: Hemiplegia|Stroke
Interventions: OTHER: Physiotherapy and Rehabilitation Practices
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 0 Study of Metronomic Oral Vinorelbine and Letrozole in HR+/HER2-negative Early Breast Cancer Patients (VENTANA)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Oral Vinorelbine|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: BAFIARS - Biomedical Assessment of Function and Imaging of the Ano-rectal Sphincter
Status: SUSPENDED
Conditions: Fecal Incontinence
Interventions: OTHER: MRI (magnetic resonance imaging)|OTHER: US (ultra sound)|OTHER: FLIP (functional lumen imaging probe)|OTHER: HRAM (high resolution anal manometry)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Outpatient Labor Induction Using Oral Misoprostol in Norway
Status: COMPLETED
Conditions: Induced; Birth|Labor, Induced
Interventions: OTHER: Outpatient labor induction|OTHER: Inpatient labor induction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epcoritamab Compared to Observation for Treating B-cell Lymphoma Patients Not in Complete Remission After CD19-directed CAR-T Therapy
Status: NOT_YET_RECRUITING
Conditions: Diffuse Large B-Cell Lymphoma, Not Otherwise Specified|Primary Mediastinal Large B-Cell Lymphoma|Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|BIOLOGICAL: Epcoritamab|PROCEDURE: Magnetic Resonance Imaging|OTHER: Patient Observation|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ICE Based Atrial Flutter Ablation Vs Conventional Fluoroscopy/Anatomical Mapping Based Ablation - ICE Flutter Study
Status: UNKNOWN
Conditions: Atrial Flutter
Interventions: PROCEDURE: 3D electroanatomical mapping alone guided CTI ablation|PROCEDURE: ICE plus 3D electroanatomical mapping guided CTI ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug-Drug Interaction Study Between ATI-2173 and Tenofovir Disoproxil Fumarate in Healthy Subjects
Status: COMPLETED
Conditions: Drug Interaction
Interventions: DRUG: ATI-2173 50 mg|DRUG: Tenofovir 300Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Application of 68Ga Labeled ssDNA Aptamer Sgc8 in Healthy Volunteers and Colorectal Patients
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: 68Ga-Sgc8
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Bioequivalence Study of Two Different Dosage Form of Genakumab
Status: RECRUITING
Conditions: Gouty Arthritis (GA)
Interventions: DRUG: Genakumab Injection (T)|DRUG: Genakumab for Injection (R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Efficacy, Safety, and Tolerability of PXT002331 (Foliglurax) in Reducing Levodopa-Induced Dyskinesia and Wearing OFF in Subjects With Parkinson's Disease Experiencing Motor Complications of Levodopa Therapy (ATTUNED)
Status: WITHDRAWN
Conditions: Parkinson Disease
Interventions: DRUG: Placebo oral capsule|DRUG: PXT002331 - 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Coccygeal Nerve Radiofrequency Treatment in Coccydynia
Status: ACTIVE_NOT_RECRUITING
Conditions: Coccyx Disorder
Interventions: PROCEDURE: Coccygeal nerve radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of ABBV-553 in Healthy Volunteers and in Subjects With Psoriasis and Efficacy of ABBV-553 in Subjects With Psoriasis
Status: TERMINATED
Conditions: Psoriasis
Interventions: DRUG: ABBV-553|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Norepinephrine and Ephedrine on Hypotension After Spinal Anesthesia in Parturients
Status: COMPLETED
Conditions: Hypotension|Obstetrical Complication of Anesthesia|Complications; Cesarean Section
Interventions: DRUG: Norepinephrine|DRUG: Ephedrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Axitinib in Treating Patients With Melanoma That is Metastatic or Cannot Be Removed by Surgery
Status: TERMINATED
Conditions: Extraocular Extension Melanoma|Metastatic Intraocular Melanoma|Recurrent Intraocular Melanoma|Recurrent Melanoma|Stage IIIA Intraocular Melanoma|Stage IIIA Melanoma|Stage IIIB Intraocular Melanoma|Stage IIIB Melanoma|Stage IIIC Intraocular Melanoma|Stage IIIC Melanoma|Stage IV Intraocular Melanoma|Stage IV Melanoma
Interventions: DRUG: axitinib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decreasing Alzheimer's Risk Through oNline Choreographed Exercise - Down Syndrome
Status: RECRUITING
Conditions: Down Syndrome|Physical Inactivity
Interventions: BEHAVIORAL: Decreasing Alzheimer's Risk Through oNline Choreographed Exercise - Down Syndrome Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prevention of Congenital Toxoplasmosis With Pyrimethamine + Sulfadiazine Versus Spiramycine During Pregnancy
Status: COMPLETED
Conditions: Congenital Toxoplasmosis
Interventions: DRUG: Pyrimethamine/Sulfadiazine|DRUG: Spiramycine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pevonedistat and Azacitidine in MDS or MDS/MPN Patients Who Fail Primary Therapy With DNA Methyl Transferase Inhibitors
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelodysplastic Syndromes|Myeloproliferative Neoplasm
Interventions: DRUG: Azacitidine Subcutaneous Injection or Intravenous Infusion|DRUG: Pevonedistat Infusion|PROCEDURE: Bone Marrow Biopsy & Aspirate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy Combined With GDP Chemotherapy in Stage I/II Extranodal Natural Killer/T-cell Lymphoma
Status: COMPLETED
Conditions: Stage I/II Extranodal NK/T-cell Lymphoma
Interventions: RADIATION: Intensity-modulated radiation therapy|DRUG: GDP chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Simvastatin and Ezetimibe on Lipid and Inflammation
Status: COMPLETED
Conditions: Prediabetes|Hypercholesterolemia|Inflammation|Cardiovascular Risk
Interventions: DRUG: Simvastatin|DRUG: Ezetimibe|DRUG: Combination Simvastatin plus Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INBONE™ Total Ankle Prosthesis With Long Talar Stem
Status: TERMINATED
Conditions: Arthritis|Infection of Total Ankle Joint Prosthesis
Interventions: DEVICE: INBONE™ Total Ankle Prosthesis with Long Talar Stem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The MEASURE Study - A Phase 3 Study of MDX 1400 mg Daily Compared With Placebo in Adults With ADHD
Status: TERMINATED
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: DRUG: MDX|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Neoplasms
Interventions: DRUG: SGM-101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Iodine Intakes on Maternal and Infant Health and the Study of Iodine RNI for Different Stages of Pregnancy
Status: UNKNOWN
Conditions: Iodine Reaction|Iodine Compounds Overdose|Pregnancy Related
Interventions: OTHER: Natural exposure of deficient or excessive iodine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improving Care Provided to Patients Treated in a Level 1 Trauma Center Post-suicide Attempt
Status: COMPLETED
Conditions: Suicidal Ideas
Interventions: BEHAVIORAL: Brief Intervention for Suicidality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Etanercept 50 mg Once Weekly to 25 mg Twice Weekly in Patients With Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Fecal Microbiota Transplantation for Severe Clostridium Difficile Associated Colitis
Status: TERMINATED
Conditions: Clostridium Difficile
Interventions: DRUG: fecal microbiota transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hormone Replacement Therapy in Relieving Menopausal Symptoms in Postmenopausal Women With Previous Stage I or Stage II Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Hot Flashes|Menopausal Symptoms|Osteoporosis
Interventions: BIOLOGICAL: therapeutic progesterone|DRUG: conjugated estrogens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combinatory Rehabilitation Used for Substantially Helping Individuals With Traumatic Brain Injury
Status: RECRUITING
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: KF-mSMT Plus Aerobic Exercise Training|BEHAVIORAL: KF-mSMT Plus Stretching Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Acupuncture Versus Sham Acupuncture in Autistic Spectrum Disorder
Status: COMPLETED
Conditions: Autistic Disorder|Autism
Interventions: PROCEDURE: Tongue Acupuncture (Procedure)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study to Evaluate Single- or Two-Dose Regimens Of RSV F Vaccine With and Without Aluminum Phosphate or Matrix-M1™ Adjuvants In Clinically-Stable Older Adults
Status: COMPLETED
Conditions: Respiratory Syncytial Viruses
Interventions: BIOLOGICAL: RSV F Vaccine with Aluminum Phosphate Adjuvant|BIOLOGICAL: RSV F Vaccine|BIOLOGICAL: Matrix-M1 Adjuvant|OTHER: Phosphate Buffer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Role of Allopurinol on Oxidative Stress and Mitochondrial Alterations in Skeletal Muscle of Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: 2 capsules of allopurinol 150 mg daily for 3 month|DRUG: 2 capsules of lactose daily for 3 month
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Study of a Personalized Neoantigen Cancer Vaccine in Treating Patients With Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer|Pancreatic Carcinoma
Interventions: BIOLOGICAL: iNeo-Vac-P01|OTHER: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Tofacitinib and Methotrexate in Takayasu's Arteritis
Status: RECRUITING
Conditions: Takayasu Arteritis
Interventions: DRUG: Tofacitinib|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Components of Metabolic Derangement and Paracentesis for Determination of Surgery in Preterm Neonates With Necrotizing Enterocolitis.
Status: TERMINATED
Conditions: Necrotizing Enterocolitis
Interventions: PROCEDURE: Association of the components of metabolic derangement and paracentesis.|PROCEDURE: Bell's criteria: pneumoperitoneum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Electrical Stimulation Of The Nerve Hypoglossal for the Treatment of Obstructive Sleep Apnea
Status: NOT_YET_RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Medtronic 8-contact Vectris subcompact or compact electrode.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Evaluation of Daclatasvir (DCV) in Combination With Sofosbuvir (SOF) in Children With Chronic Hepatitis C (CHC) Infection
Status: TERMINATED
Conditions: Hepatitis C|Chronic Hepatitis
Interventions: DRUG: Daclatasvir|DRUG: Sofosbuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Naropin and Ketorolac for Postoperative Analgesia After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Ketorolac|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Should Prosthetic Repair of Incisional Abdominal Hernias be Drain or Not?
Status: COMPLETED
Conditions: Postoperative Complications|Hernia
Interventions: PROCEDURE: Prosthetic repair of abdominal incisional hernia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bracing in Adolescent Idiopathic Scoliosis Trial (BrAIST)
Status: TERMINATED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: DEVICE: Brace|OTHER: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Geriatric Assessmen of Elderly "Unsuited" Patients Receiving Trabectedin in First Line Treatment For Advanced Soft Tissue Sarcomas (STS)
Status: COMPLETED
Conditions: Advanced Soft-tissue Sarcoma|Metastatic Soft-tissue Sarcoma
Interventions: OTHER: No Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability and Pharmacokinetics of Injectable PEG-Irinotecan (JK-1201I) in Patients with Malignant Solid Tumor
Status: COMPLETED
Conditions: Solid Tumor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study of Pacritinib Combined With Ibrutinib in Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)
Status: WITHDRAWN
Conditions: Chronic Lymphocytic Leukemia|Lymphoma, Small Lymphocytic
Interventions: DRUG: Pacritinib|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trametinib, Fluorouracil, and Radiation Therapy Before Surgery in Treating Patients With Stage II-III Rectal Cancer
Status: COMPLETED
Conditions: Recurrent Rectal Cancer|Stage IIA Rectal Cancer|Stage IIB Rectal Cancer|Stage IIC Rectal Cancer|Stage IIIA Rectal Cancer|Stage IIIB Rectal Cancer|Stage IIIC Rectal Cancer
Interventions: DRUG: trametinib|DRUG: fluorouracil|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Three Different Peak Airway Pressures on Determining Intraoperative Bleeding in Thryroidectomies
Status: COMPLETED
Conditions: Thyroid Neoplasms|Thyroid Nodule
Interventions: PROCEDURE: peak airway pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of a Brief Post Traumatic Stress Disorder Intervention for Use in Botswana
Status: UNKNOWN
Conditions: Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: Brief Relaxation, Education And Trauma HEaling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of BEMER and Kinesiotape in Increasing the Effectiveness of Physiotherapy and Rehabilitation Program After Videothoracoscopy Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain, Post Operative
Interventions: OTHER: Control Group|OTHER: BEMER Group|OTHER: Kinesiotape Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 10-week Leucine Supplementation in Cerebral Palsy
Status: UNKNOWN
Conditions: Cerebral Palsy|Cerebral Palsy, Mixed|Cerebral Palsy Ataxic
Interventions: DIETARY_SUPPLEMENT: Leucine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation Training Games for Children With Amblyopia
Status: RECRUITING
Conditions: Amblyopia|Amblyopia Occlusion|Child Behavior|Adherence, Treatment
Interventions: DEVICE: Find You! Cure My Animal Friends|DEVICE: DuoBao Vision Training System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effectiveness of a Mobile Interactive Supervised Therapy (MIST) Intervention for Improving Adherence to HIV Medication
Status: COMPLETED
Conditions: HIV-infection/Aids
Interventions: BEHAVIORAL: Mobile Interactive Supervised Therapy (MIST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adjuvant Target Therapy Guided by ctDNA-MRD in Patients With EGFR-mutant II-IIIA Non-small Cell Lung Cancer (ECTOP-1022)
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer|EGFR Gene Mutation|Minimal Residual Disease
Interventions: DRUG: Osimertinib|DRUG: No adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perfetti Method on Upper Extremity Spasticity of Stroke Patient
Status: COMPLETED
Conditions: Stroke Syndrome Sequela Spasticity
Interventions: OTHER: Perfetti method|OTHER: passive stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant MEDI4736 Concomitant With Weekly Nab-paclitaxel and Dose-dense AC for Stage I-III Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: MEDI4736
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess the Activity and Safety of Palbociclib in Patients With Well and Moderately Differentiated Metastatic Pancreatic Neuroendocrine Tumors (pNET)
Status: COMPLETED
Conditions: Pancreatic Neuroendocrine Cancer
Interventions: DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Pridopidine (ACR16) for the Treatment of Participants With Huntington's Disease
Status: COMPLETED
Conditions: Huntington Disease
Interventions: DRUG: ACR16|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SU011248 In The Treatment Of Patients With Bevacizumab (Avastin)-Refractory Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Logotherapy Based Psychosocial Support Program on Nursing Students on the Meaning of Life and Life Satisfaction
Status: COMPLETED
Conditions: Meaning of Life and Life Satisfaction
Interventions: BEHAVIORAL: The existential approach and logotherapy-based psychosocial support program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Surufatinib and Sintilimab in Combination With Capecitabine for Metastatic Adenocarcinoma of Small Intestine or Appendix Carcinoma
Status: RECRUITING
Conditions: Adenocarcinoma of Small Intestine|Appendix Carcinoma|Metastatic
Interventions: DRUG: Surufatinib|DRUG: Sintilimab|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Continuous and Pulsed Radiofrequency Ablation for Pain Relief and Their Safety in Cervical Facet Pain
Status: COMPLETED
Conditions: Radiofrequency Ablation
Interventions: PROCEDURE: Flouroscopic guidance cervical medial branch radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Bilateral Multifocal Intraocular Lenses and Pseudophakic Monovision
Status: UNKNOWN
Conditions: Cataract
Interventions: PROCEDURE: Bilateral cataract surgery with implantation of multifocal IOLs|PROCEDURE: Bilateral cataract surgery with monovision|DEVICE: Lentis LS-313
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Structured Exercise Training Programme in Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Breathlessness|Quality of Life|Idiopathic Pulmonary Fibrosis
Interventions: OTHER: Structured Responsive Exercise Training|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conventional Versus Elastography Targeted Endoscopic Ultrasound Fine Needle Aspiration of Solid Pancreatic Lesions
Status: UNKNOWN
Conditions: Pancreas Cancer
Interventions: DEVICE: RTE-guided EUS-FNA|DEVICE: Conventional EUS-FNA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Laser vs. Electorsurgical Enbloc Resection of Bladder Tumours
Status: UNKNOWN
Conditions: Urinary Bladder Neoplasm
Interventions: PROCEDURE: Laser En Bloc Resection Of bladder Tumor|PROCEDURE: Electro-surgical En Bloc Resection Of bladder Tumor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bortezomib, Doxorubicin Hydrochloride Liposome, and Thalidomide as First-line Therapy in Treating Patients With Previously Untreated Stage I, II, or III Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: bortezomib|DRUG: pegylated liposomal doxorubicin hydrochloride|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: E-STIM Trial: Comparing the Efficacy of the Empi Select TENS to a Control for the Treatment of Chronic Lower Back Pain
Status: UNKNOWN
Conditions: Lower Back Pain
Interventions: DEVICE: Empi Select TENS Device|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxidative Stress, Low Grade Inflammation, Tissue Breakdown and Biomarkers in Cerebrospinal Fluid of A-T
Status: COMPLETED
Conditions: Ataxia Telangiectasia
Interventions: PROCEDURE: Lumbar puncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Evaluation of an Electric and a Manual Toothbrush in Removal of Dental Plaque
Status: COMPLETED
Conditions: Plaque, Dental
Interventions: DIAGNOSTIC_TEST: Manual toothbrush|DIAGNOSTIC_TEST: Electric toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING