pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Adding Magnesium Sulfate to Bupivacaine in Ultrasound Guided Paravertebral Block for Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: DRUG: Bupivacain|DRUG: magnesium sulfate|OTHER: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Online Hemodiafiltration Versus Hemodialysis in Removal of Indoxyl Sulfate in Chronic Hemodialysis Patients
Status: COMPLETED
Conditions: Hemodialysis
Interventions: PROCEDURE: online hemodiafiltration|PROCEDURE: high flux hemodialysis|PROCEDURE: low flux hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin, Bevacizumab, and Gemcitabine Followed by Surgery, Bevacizumab, and Paclitaxel in Treating Patients With Locally Advanced Nonmetastatic Bladder Cancer That Can Be Removed By Surgery
Status: TERMINATED
Conditions: Bladder Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: cisplatin|DRUG: gemcitabine hydrochloride|DRUG: paclitaxel|PROCEDURE: cysectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TXA in the Reduction of Post-Op Hematoma and Seroma in Patients Undergoing Panniculectomy or Abdominoplasty
Status: TERMINATED
Conditions: Panniculectomy|Abdominoplasty
Interventions: DRUG: Tranexamic acid|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison Between Gastric and Post Pyloric Tube Feedings in Children With Bronchiolitis Requiring High Flow Nasal Cannula
Status: TERMINATED
Conditions: Enteral Feeding in Bronchiolitis
Interventions: DEVICE: Nasogastric tube (NGT) feeding|DEVICE: Nasoduodenal tube (NDT) feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pharmacokinetics, Safety and Tolerability of AGO178C in Subjects With Renal Deficiencies Compared With Healthy Subjects
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: AGO178C
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Perioperative Lenvatinib With Pembrolizumab in Patients With Locally Advanced Nonmetastatic Clear Cell Renal Cell Carcinoma
Status: RECRUITING
Conditions: Kidney Cancer|Stage III Renal Cell Cancer AJCC v8|Stage IV Renal Cell Cancer AJCC v8
Interventions: DRUG: Lenvatinib|DRUG: Lenvatinib Mesylate|BIOLOGICAL: Pembrolizumab|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intact Cord Resuscitation in CDH
Status: RECRUITING
Conditions: Rare Diseases|Congenital Diaphragmatic Hernia
Interventions: PROCEDURE: Immediate umbilical cord clamping|PROCEDURE: intact cord resuscitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SD-OCT-guided Intravitreal Ranibizumab Treatment in Choroidal Neovascularization Due to Myopia
Status: COMPLETED
Conditions: Choroidal Neovascularization|Age Related Macular Degeneration
Interventions: DRUG: Ranibizumab, Lucentis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Depemokimab (GSK3511294) in Participants With Chronic Rhinosinusitis With Nasal Polyps
Status: ACTIVE_NOT_RECRUITING
Conditions: Nasal Polyps
Interventions: BIOLOGICAL: Depemokimab (GSK3511294)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Operational Feasibility of Appropriate Plasmodium Vivax Radical Cure After G6PD Testing in Thailand
Status: COMPLETED
Conditions: Malaria, Vivax|G6PD Deficiency
Interventions: DRUG: Tafenoquine|DRUG: Primaquine|DRUG: Primaquine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Scar Results and Time for Closures of Scalp Defects Via Pulley Sutures or Layered Repairs
Status: COMPLETED
Conditions: Scar
Interventions: PROCEDURE: Pulley stitches|PROCEDURE: Intermediate Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ketorolac on Post Adenotonsillectomy Pain
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Ketorolac|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety (Compared to Iron Sucrose), Efficacy and Pharmacokinetics of Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects With Chronic Kidney Disease (CKD)
Status: RECRUITING
Conditions: Chronic Kidney Disease; Iron Deficiency Anemia
Interventions: DRUG: Ferumoxytol|DRUG: Iron sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Dabrafenib, Trametinib and Metformin for Melanoma Patients
Status: WITHDRAWN
Conditions: Melanoma
Interventions: DRUG: Dabrafenib|DRUG: Trametinib|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of the Fully Human Anti-tetanus Toxin Monoclonal Antibody A82 / B86 Injection Combination Formulation
Status: NOT_YET_RECRUITING
Conditions: Clostridium Tetanus
Interventions: DRUG: Human anti-tetanus toxin monoclonal antibody A82 / B86 injection combination preparation|DRUG: Tetanus human immunoglobulin (HTIG)|DRUG: Whole-human anti-tetanus toxin monoclonal antibody A82 / B86 injection placebo|BIOLOGICAL: Adsorbed tetanus vaccine (TT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exploring the Utility of [18F]3F4AP for Demyelination Imaging in Controls, Neurodegeneration and Traumatic Brian Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain Injuries, Traumatic|Demyelinating Disorder|Alzheimer Disease
Interventions: DRUG: F18-3F4AP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prexasertib in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors
Status: COMPLETED
Conditions: Childhood Solid Neoplasm|Recurrent Malignant Solid Neoplasm|Recurrent Primary Central Nervous System Neoplasm|Refractory Malignant Solid Neoplasm|Refractory Primary Central Nervous System Neoplasm
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacokinetic (PK) study|DRUG: Prexasertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Action Observation Treatment (AOT) as a Rehabilitation Tool
Status: UNKNOWN
Conditions: Stroke, Acute Hemiplegia, Apraxia
Interventions: OTHER: Action Observation Treatment (AOT)|OTHER: Observation of videos with no motor content (MNO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Multidisciplinary Translational Approach to Investigate Mechanisms Predictors & Prevention of Persistent PTH
Status: RECRUITING
Conditions: Post-Traumatic Headache
Interventions: DRUG: Erenumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics After Single and Multiple Doses of LEO 142397 in Healthy People, Including Japanese
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: LEO 142397|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Cost-effectiveness of Group Schema Therapy for Complex Eating Disorders: the GST-EAT Study
Status: RECRUITING
Conditions: Anorexia Nervosa|Atypical Anorexia Nervosa (Other Specified Eating Disorder)|Bulimia Nervosa|Atypical Bulimia Nervosa (Other Specified Eating Disorder)
Interventions: BEHAVIORAL: GST|BEHAVIORAL: CBT-E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Polypodium Leucotomos for Melasma
Status: COMPLETED
Conditions: Melasma
Interventions: DIETARY_SUPPLEMENT: Polypodium Leucotomos|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Air Pollution and Cardiovascular Disease in Qatar: an Interventional Study to Reduce Blood Pressure
Status: RECRUITING
Conditions: Hypertension, Systolic|Metabolic Syndrome
Interventions: DEVICE: Air cleaners with HEPA filter|DEVICE: Air cleaners without HEPA filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Swallowed Steroids on Bone Density and Growth in Pediatric Eosinophilic Esophagitis
Status: UNKNOWN
Conditions: Eosinophilic Esophagitis
Interventions: DIAGNOSTIC_TEST: Bone Mineral Density (DEXA) scan|DIAGNOSTIC_TEST: Vitamin D Measurement|DIAGNOSTIC_TEST: Height measurement|OTHER: Assessment of medication compliance
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: "Loss of Resistance" Versus CompuFlo® for Epidural Placement
Status: WITHDRAWN
Conditions: Pain|Epidural Analgesia
Interventions: DEVICE: 18G Tuohy epidural needle|DEVICE: CompuFlo® computerized syringe pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Utility of Point Shear-wave Elastography to Assess for Hepatic & Pancreatic Fibrosis in Pediatric CF Patients
Status: UNKNOWN
Conditions: Cystic Fibrosis|Cystic Fibrosis Liver Disease|Pancreatic Insufficiency Due to Cystic Fibrosis of Pancreas
Interventions: DIAGNOSTIC_TEST: Elastography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Psychobiology of Stress and Alcohol Craving
Status: COMPLETED
Conditions: Alcohol Use Disorder|Stress Reaction|Social Stress|Craving|Behavior
Interventions: BEHAVIORAL: Trier Social Stress Test|BEHAVIORAL: Reading Newspaper|BEHAVIORAL: Barlab-Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of UroLift: LIFT Pivotal Study
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DEVICE: UroLift System|OTHER: Cystoscopy|DEVICE: Crossover
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Efficacy of JBT-101 (Lenabasum) in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: JBT-101 (lenabasum)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Second Generation Human Milk Oligosaccharides Blend Study
Status: COMPLETED
Conditions: Healthy Infants
Interventions: OTHER: Starter Infant Formula, Follow-up Formula, and Growing-up Milk Supplemented With a Blend of Five Human Milk Oligosaccharides|OTHER: Breast-feeding|OTHER: Standard Starter Infant Formula, Follow-up Formula, and Growing-up Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Ultrasound-Guided Serratus Anterior Plane Block in Pneumothorax Surgery
Status: UNKNOWN
Conditions: Analgesia|Postoperative Pain|Pneumothorax
Interventions: PROCEDURE: Single Port Video-Assisted Thoracoscopic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of a Booster Dose of Hib-MenC Conjugate Vaccine vs Infanrix Hexa When Given to 14 Month Old Subjects
Status: COMPLETED
Conditions: Neisseria Meningitidis|Haemophilus Influenzae Type b
Interventions: BIOLOGICAL: Haemophilus influenzae type b- and meningococcal (vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Partial Versus Complete Pulpotomy in Carious Immature Molars Permanent Teeth Using Bioceramic Material
Status: NOT_YET_RECRUITING
Conditions: Carious Teeth
Interventions: PROCEDURE: partial pulpotomy|PROCEDURE: Complete pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Factor VIIa on Rebleeding After Surgery for Spontaneous Intracerebral Hemorrhage (ICH)
Status: COMPLETED
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: rFactor VIIa (Eptacog alfa, NovoNordisk)|DRUG: rFVIIa|OTHER: Sodiun chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Osteosarcopenia in Axial Spondyloarthritis
Status: RECRUITING
Conditions: Axial Spondyloarthritis|Ankylosing Spondylitis|Axial Spondyloarthritis, Non-Radiographic|Osteoporosis|Sarcopenia|Osteosarcopenia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Human Algorithm Interactions for Acute Respiratory Failure Diagnosis
Status: COMPLETED
Conditions: Acute Respiratory Failure
Interventions: OTHER: Artificial Intelligence model predictions without explanation|OTHER: Artificial intelligence model predictions with explanation|OTHER: AI model biased against heart failure|OTHER: AI model biased against pneumonia|OTHER: AI model biased against COPD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Effect of Mobilized Stem Cell by G-CSF and VEGF Gene Therapy in Patients With Stable Severe Angina Pectoris
Status: COMPLETED
Conditions: Ischemic Heart Disease
Interventions: GENETIC: VEGF-A165 plasmid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Refractive Change Induced by 2.8-mm Corneal Incision
Status: COMPLETED
Conditions: Cataract|Refractive Surgery|Astigmatism
Interventions: PROCEDURE: Nasal 2.8-mm corneal incision|PROCEDURE: Temporal 2.8-mm corneal incision|PROCEDURE: Superior 2.8-mm incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intrarectal Misoprostol in Postpartum Haemorrhage
Status: COMPLETED
Conditions: Postpartum Haemorrhage
Interventions: DRUG: Misoprostol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of the Cheetah NICOM by Comparison to TEE During Open Vascular Surgery - Pilot Study
Status: UNKNOWN
Conditions: Aortic Aneurysm|Peripheral Arterial Disease
Interventions: DEVICE: Cheetah NICOM|DEVICE: Transesophageal echocardiography (TEE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Management of Breathlessness With High-flow Nasal Therapy or a Fan
Status: RECRUITING
Conditions: Breathlessness|Cancer
Interventions: DEVICE: High-flow nasal therapy|DEVICE: Airflow directed to face by a fan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Any Potential Interaction Between Colesevelam and Ciclosporin in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Colesevelam hydrochloride film-coated tablets (Cholestagel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Examining the Benefit of Graduated Compression Stockings in the Prevention of vEnous Thromboembolism in Low-risk Surgical Patients
Status: RECRUITING
Conditions: Venous Thromboembolism
Interventions: OTHER: Graduated Compression Stockings - Thromboembolic deterrent stockings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Modified Kinesio Taping Technique on Morbidity After Impacted Third Molar
Status: COMPLETED
Conditions: Impacted Third Molar Tooth
Interventions: DEVICE: Kinesio taping|DEVICE: Wound Tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of MEDI8968 in Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BIOLOGICAL: MEDI8968 600 mg IV, 300 mg SC|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extra-abdominal Removal of Placenta During CS
Status: COMPLETED
Conditions: the Influence of Intra- vs Extra-abdominal Removal of Placenta|Duration of Operation|the Amount of Aspirated Fluid During the Operation|Difference Between Pre- and Post-operative CBC
Interventions: PROCEDURE: Extra-abdominal removal of the placenta|PROCEDURE: Extra-abdominal removal of the placenta|PROCEDURE: Extra-abdominal removal of the placenta|PROCEDURE: Extra-abdominal removal of the placenta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study To Assess the Immune Response Following Administration Of Influenza and Pneumococcal Vaccines To Subjects With Rheumatoid Arthritis Receiving CP-690,550 Or Placebo
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: CP-690,550|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of HYDROLINK™ and HeprAN™ mEmbranes in a Per Dialytic Heparin Weaning Strategy in Chronic Hemodialysis Patients
Status: RECRUITING
Conditions: Renal Insufficiency
Interventions: DEVICE: Decrease per-dialytic heparin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Children With Moderate Acute Malnutrition in Mali
Status: COMPLETED
Conditions: Moderate Acute Malnutrition (MAM)
Interventions: DIETARY_SUPPLEMENT: Plumpy'Sup|DIETARY_SUPPLEMENT: Local food supplement|DIETARY_SUPPLEMENT: Misola|DIETARY_SUPPLEMENT: SCSB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Relative Bioavailability of ASC41 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ASC41|DRUG: ASC41 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of MRx-4DP0004 in Asthma
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: MRx-4DP0004|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of BI 44847 in Different Ethnic Groups and Evaluation of Effect of Diet and Acarbose Coadministration on Bioavailability Following Oral Administration of 200 mg BI 44847 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 44847|DRUG: Acarbose|OTHER: Japanese diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of U-Shaped Sonic Toothbrush on Plaque and Gingivitis
Status: COMPLETED
Conditions: Plaque Induced Gingivitis
Interventions: DEVICE: Power sonic toothbrush|DEVICE: Manual toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Insulin Sensitivity by Non-invasive Brain Stimulation
Status: COMPLETED
Conditions: Insulin Resistance|Transcranial Direct Current Stimulation|Obesity|Diabetes|Magnetic Resonance Imaging
Interventions: DEVICE: transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Systemic Fluoride Bioavailability From Toothpastes Containing Calcium Carbonate or Silica as Abrasives
Status: COMPLETED
Conditions: Dental Fluorosis
Interventions: DRUG: Purified water|DRUG: Fresh MFP/CaCO3 toothpaste|DRUG: Fresh NaF/SiO2 toothpaste|DRUG: Aged NaF/SiO2 toothpaste|DRUG: Aged MFP/CaCO3 toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Post-tonsillectomy Pain Control in Adults
Status: TERMINATED
Conditions: Pain, Postoperative|Postoperative Nausea and Vomiting|Postoperative Hemorrhage|Body Weight Changes
Interventions: DRUG: Norco (Hydrocodone and Acetaminophen)|DRUG: Percocet (Oxycodone and Acetaminophen)|DRUG: Dilaudid (hydromorphone)|DRUG: Tylenol (Acetaminophen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nipple-Areola Complex Sensitivity After the Section of Periareolar Dermis in Breast Reduction
Status: UNKNOWN
Conditions: Sensitivity of Nipple-areolar Complex
Interventions: PROCEDURE: Section of Periareolar Dermis in Breast Reduction.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aflibercept in Polypoidal Choroidal Vasculopathy
Status: COMPLETED
Conditions: Neovascular Macular Degeneration
Interventions: DRUG: Aflibercept (Eylea, VEGF Trap-Eye, BAY86-5321)|OTHER: Visudyne
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ischemic Preconditioning as an Intervention to Improve Stroke Rehabilitation - Froedtert
Status: COMPLETED
Conditions: Stroke Rehabilitation|Ischemic Preconditioning|Physical and Rehabilitation Medicine
Interventions: OTHER: Ischemic Preconditioning|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Alert-Based Computerized Decision Support for Patients With Peripheral Artery Disease Not Prescribed Lipid-Lowering Therapy
Status: RECRUITING
Conditions: Peripheral Artery Disease|Peripheral Vascular Diseases|Dyslipidemias
Interventions: BEHAVIORAL: Computer Alert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Lipid Lowering Effect of Rosuvastatin Compared to Atorvastatin in Subjects With Coronary Heart Disease
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DRUG: Rosuvastatin or atorvastatin or simvastatin and clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: PLAY Therapy Intervention: Re-Modelling Patient Experience (The PLAYTIME Study)
Status: WITHDRAWN
Conditions: Pain|Anxiety|Rheumatology
Interventions: BEHAVIORAL: Play therapy|BEHAVIORAL: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability, and Blood Levels of Ritonavir-Boosted Atazanavir and Rifampin When Taken Together in HIV Uninfected Adults
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: Atazanavir|DRUG: Rifampin|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Response in Humans With Obesity
Status: RECRUITING
Conditions: Obese
Interventions: DIAGNOSTIC_TEST: Treadmill Test|DIAGNOSTIC_TEST: Strength Test|DIAGNOSTIC_TEST: Dual-Energy X-Ray Absorptiometry|PROCEDURE: Muscle Biopsy|PROCEDURE: Fat Biopsy|DIAGNOSTIC_TEST: Resting Energy Expenditure|DIAGNOSTIC_TEST: Magnetic resonance imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Calisthenics Versus High Intensity Interval Training in NAFL
Status: RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: OTHER: Calisthenics exercise and High intensity interval training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: READYorNot[TM] Brain-Based Disabilities Trial
Status: TERMINATED
Conditions: Autism Spectrum Disorder|Cerebral Palsy|Epilepsy|Fetal Alcohol Spectrum Disorders|Spina Bifida
Interventions: OTHER: e-health application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Noscapine for Patients With Low Grade Non Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia Refractory to Chemotherapy
Status: TERMINATED
Conditions: Non-Hodgkin's Lymphoma|Chronic Lymphocytic Leukemia
Interventions: DRUG: Noscapine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomechanical Analysis of Arterial Tissue From Patient Suffering From Peripheral Artery Disease in the Lower Limb
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: OTHER: Biomechanical analysis of femoralis superficialis atherosclerotic tissue|RADIATION: CT or MR angiogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anti-IMP3 Autoantibody and MicroRNA Signature Blood Tests in Finding Metastasis in Patients With Localized or Metastatic Kidney Cancer
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: GENETIC: gene expression analysis|GENETIC: protein expression analysis|DIAGNOSTIC_TEST: diagnostic laboratory biomarker analysis|OTHER: immunoenzyme technique|OTHER: immunohistochemistry staining method
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Physics Forceps vs Conventional Forceps in Extraction of Mandibular Molars
Status: COMPLETED
Conditions: Tooth Extraction
Interventions: PROCEDURE: Extraction of Mandibular Molar using Physics Forceps|PROCEDURE: Extraction of Mandibular Molar using Conventional Forceps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endobronchial Ultrasound Needle Aspiration With and Without Suction
Status: UNKNOWN
Conditions: Mediastinal Lymphadenopathy|Hilar Lymphadenopathy|Lymphoma|Lung Neoplasms|Sarcoidosis|Tuberculosis|EGF-R Positive Non-Small Cell Lung Cancer|PDL1 Gene Mutation|ALK Translocation|ROS1 Gene Mutation
Interventions: PROCEDURE: No suction EBUS-TBNA|PROCEDURE: Passive suction through dedicated EBUS-TBNA syringe|PROCEDURE: Manual applied suction EBUS-TBNA through a pistol-grip syringe holder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Inhaled Aviptadil for the Treatment of COVID-19 in Patients at High Risk for ARDS
Status: TERMINATED
Conditions: Covid19|Corona Virus Infection|ARDS|Aviptadil
Interventions: DRUG: Aviptadil 67μg|DRUG: Placebo 0.9% NaCl solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Collagen-thrombin Matrix Efficacy During Cardiac Surgery: a Prospective Randomized Controlled Trial
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Collastat|DEVICE: Floseal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Aged Garlic Extract Study
Status: COMPLETED
Conditions: Coronary Artery Disease|Microcirculation|Biomarkers
Interventions: DIETARY_SUPPLEMENT: Aged Garlic Extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluating the Analgesic Efficacy of Combined Individual Nerve Block in Comparison to Interscalene Nerve Block
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: interscalene block|PROCEDURE: selective nerve block|DRUG: bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Butyphthalide in Combination With Recombinant Tissue Plasminogen Activator for Acute Ischemic Stroke
Status: COMPLETED
Conditions: Stroke, Ischemic
Interventions: DRUG: Butyphthalide combined with rtPA|DRUG: rtPA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bone Density and Bone Loss in Postmenopausal Women With Breast Cancer Receiving Treatment in Clinical Trial IBCSG-1-98
Status: COMPLETED
Conditions: Breast Cancer|Osteoporosis
Interventions: OTHER: laboratory biomarker analysis|PROCEDURE: Dual energy X-ray absorptiometry (DEXA)|PROCEDURE: Spine X-ray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Observational Prospective Research Study In Monoclonal Gammopathies leadINg to Myeloma
Status: RECRUITING
Conditions: Monoclonal Gammopathy of Undetermined Significance|Smoldering Plasma Cell Myeloma
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Paricalcitol in Reducing Parathyroid Hormone Levels and Ameliorating Markers of Bone Remodelling in Renal Transplant Recipients With Secondary Hyperparathyroidism
Status: COMPLETED
Conditions: Renal Transplant|Secondary Hyperparathyroidism
Interventions: DRUG: Paricalcitol|DRUG: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Injection Site Tolerability, Safety, Pharmacokinetics, Pharmacodynamics in Different Single-Dose Treatments of Alirocumab SAR236553 (REGN727) in Healthy Subjects
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: alirocumab SAR236553 (REGN727)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Clonidine and Propranolol in Dentistry (AAA)
Status: UNKNOWN
Conditions: Anxiety
Interventions: DRUG: Clonidine|DRUG: Propranolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ropivacaine Versus Ropivacaine Plus Mepivacaine for Sciatic Block
Status: COMPLETED
Conditions: Subgluteal Sciatic Block
Interventions: DRUG: ropivacaine|DRUG: ropivacaine plus mepivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Dietary Supplement Containing Salacia Extract, Citrus Bioflavonoids, and Trivalent Chromium on Markers of Glucose Control
Status: COMPLETED
Conditions: Glucose Intolerance
Interventions: DIETARY_SUPPLEMENT: Active|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prepare to Care, A Supported Self-Management Intervention for Head and Neck Cancer CaregiversHead and Neck Cancer
Status: COMPLETED
Conditions: Caregiver|Malignant Head and Neck Neoplasm|Paranasal Sinus Squamous Cell Carcinoma|Salivary Gland Squamous Cell Carcinoma|Stage I Hypopharyngeal Squamous Cell Carcinoma|Stage I Laryngeal Squamous Cell Carcinoma|Stage I Lip and Oral Cavity Squamous Cell Carcinoma|Stage I Oropharyngeal Squamous Cell Carcinoma|Stage II Hypopharyngeal Squamous Cell Carcinoma|Stage II Laryngeal Squamous Cell Carcinoma|Stage II Lip and Oral Cavity Squamous Cell Carcinoma|Stage II Oropharyngeal Squamous Cell Carcinoma|Stage III Hypopharyngeal Squamous Cell Carcinoma|Stage III Laryngeal Squamous Cell Carcinoma|Stage III Lip and Oral Cavity Squamous Cell Carcinoma|Stage III Oropharyngeal Squamous Cell Carcinoma|Stage IV Hypopharyngeal Squamous Cell Carcinoma|Stage IV Laryngeal Squamous Cell Carcinoma|Stage IV Lip and Oral Cavity Squamous Cell Carcinoma|Stage IV Oropharyngeal Squamous Cell Carcinoma|Stage IVA Hypopharyngeal Squamous Cell Carcinoma|Stage IVA Laryngeal Squamous Cell Carcinoma|Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma|Stage IVA Oropharyngeal Squamous Cell Carcinoma|Stage IVB Hypopharyngeal Squamous Cell Carcinoma|Stage IVB Laryngeal Squamous Cell Carcinoma|Stage IVB Lip and Oral Cavity Squamous Cell Carcinoma|Stage IVB Oropharyngeal Squamous Cell Carcinoma|Stage IVC Hypopharyngeal Squamous Cell Carcinoma|Stage IVC Laryngeal Squamous Cell Carcinoma|Stage IVC Lip and Oral Cavity Squamous Cell Carcinoma|Stage IVC Oropharyngeal Squamous Cell Carcinoma|Recurrent Head and Neck Squamous Cell Carcinoma|Recurrent Hypopharyngeal Squamous Cell Carcinoma|Recurrent Laryngeal Squamous Cell Carcinoma|Recurrent Lip and Oral Cavity Squamous Cell Carcinoma|Recurrent Oropharyngeal SCC|Recurrent Paranasal Sinus Squamous Cell Carcinoma
Interventions: OTHER: Communication Intervention|OTHER: Watch video|OTHER: Module completion of the Prepare to Care kit|OTHER: Quality-of-Life Assessment|OTHER: Survey Administration|OTHER: Salivary cortisol collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Test Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Intravenous Doses of Zampilimab in Healthy Participants
Status: COMPLETED
Conditions: Healthy Study Participants
Interventions: DRUG: Zampilimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Levetiracetam in the Management of Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Depression
Interventions: DRUG: Levetiracetam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-articular Transplantation of Autologous Adipose Derived Stromal Vascular Faction (SVF) for Treatment of Osteoarthritis of the Knee
Status: RECRUITING
Conditions: Osteo Arthritis Knee|Degenerative Joint Disease of Knee
Interventions: BIOLOGICAL: Autologous Adipose-Derived SVF (Stromal Vascular Fraction)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Additional Chinese Formula for Concurrent Chemoradiotherapy in Oral Cavity Cancer Patients
Status: COMPLETED
Conditions: Head and Neck Neoplasm|Chemoradiotherapy
Interventions: DRUG: SZKJT(San-Zhong-Kui-Jian-Tang)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Evaluating the Combination of Encorafenib and Cetuximab Versus Irinotecan/Cetuximab or Infusional 5-fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab in Chinese Patients With BRAF V600E Mutant Metastatic Colorectal Cancer.
Status: ACTIVE_NOT_RECRUITING
Conditions: BRAF V600E|Metastatic Colorectal Cancer
Interventions: DRUG: Encorafenib|DRUG: Cetuximab|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose, Dose Escalation Study of Varenicline Controlled Release Formulation in Adult Smokers
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Varenicline Tartrate|DRUG: Varenicline Tartrate|DRUG: Varenicline Tartrate|DRUG: Varenicline Tartrate|DRUG: Varenicline Tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Nursing Advice for University Students With Depressive Symptoms
Status: UNKNOWN
Conditions: Depressive Symptoms
Interventions: BEHAVIORAL: 5-mins brief nursing advice incorporating with Social Cognitive Theory (SCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PLATO - Medication Adherence in Transplant Recipients
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Disease, Chronic|Medication Adherence|Renal Disease|Kidney Rejection Transplant
Interventions: BEHAVIORAL: Tailored medication adherence plan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Belatacept Evaluation of Nephroprotection and Efficacy as First-line Immunosuppression (BENEFIT)
Status: COMPLETED
Conditions: Kidney Transplantation|Chronic Kidney Failure
Interventions: DRUG: Cyclosporine (CsA)|DRUG: Belatacept LI (less intensive)|DRUG: Belatacept MI (more intensive)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: SSRI Effects on Depression and Immunity in HIV/AIDS
Status: COMPLETED
Conditions: Depression|HIV|AIDS
Interventions: DRUG: Escitalopram|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Narcotrend and Cerebral Function Analysing Monitor in Intensive Care to Monitor Seizures and Deep Sedation
Status: RECRUITING
Conditions: Traumatic Brain Injury|Subarachnoid Hemorrhage|Intracerebral Haemorrhage|Encephalitis|Acute Ischemic Stroke|Status Epilepticus|Seizures|Subdural Hematoma|ICP (Intracranial Pressure) Increase
Interventions: DIAGNOSTIC_TEST: Narcotrend compared to Cerebral Function Analysing Monitor (CFAM)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The SMART ART Study
Status: RECRUITING
Conditions: HIV|ART
Interventions: OTHER: Home delivery of ART|OTHER: Smart Lockers (Pele boxes)|OTHER: Best clinic practices + conditional lottery incentives|OTHER: Best clinic practices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Trial of Laparoscopic Pelvic and Para-aortic Lymphadenectomy and Uterine Blood Vessel Blocking for Precision Diagnosis and Treatment in Advanced Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer, Stage IIB|Cervical Cancer Stage IIIA|Cervical Cancer Stage IIIB|Cervical Cancer, Stage IVA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Time-restricted Eating Study (TRES): Impacts on Anthropometric, Cardiometabolic and Cardiovascular Health
Status: RECRUITING
Conditions: Myocardial Infarction
Interventions: BEHAVIORAL: Time-restricted eating 10-hr
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Conventional-therapy & FES-therapy In-Veritas Effects Study
Status: RECRUITING
Conditions: C5 Palsy
Interventions: DEVICE: Functional electrical stimulation therapy (FES-t)|OTHER: Conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Precision RT For Soft-Tissue Sarcoma
Status: COMPLETED
Conditions: Soft-Tissue Sarcoma
Interventions: RADIATION: Intensity-Modulated Radiotherapy|RADIATION: Daily Cone Beam CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weight Adjusted Low Molecular Weight Heparin in Recurrent Implantation Failure: a Randomized Open Labeled Trial
Status: TERMINATED
Conditions: Infertility|Low Molecular Weight Heparin
Interventions: DRUG: Parnaparin Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of LIK066 on Reduction of Fatty Content in Livers of Obese Patients
Status: COMPLETED
Conditions: Obese Patients With Non-alcoholic Steatohepatitis (NASH)
Interventions: DRUG: LIK066|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assess Incidence of Deep Vein Thrombosis(DVT)Following Administration of Recombinant Human Antithrombin (rhAT) to Hereditary Antithrombin(AT) Deficient Patients in High Risk Situations.
Status: COMPLETED
Conditions: Antithrombin Deficiency, Congenital
Interventions: BIOLOGICAL: Recombinant Human Antithrombin (rhAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Investigation Study to Evaluate the Consistency and Reproducibility of Two Consecutive Mosquito Feeding Assays
Status: COMPLETED
Conditions: Malaria
Interventions: OTHER: Direct Skin Feeding Assay (DSFA)|DRUG: Primaquine|DRUG: Artemether/Lumefantrine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Accuracy of CVC Depth Prediction in Internal Jugular Veins: The Difference Between The Andropoulos and ECG Methods
Status: COMPLETED
Conditions: Depth of CVC Insertion
Interventions: OTHER: andropulous method|DEVICE: ECG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Levetiracetam Versus Placebo on Levodopa-induced Dyskinesias in Advanced Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Susceptibility-Guided Therapy for Helicobacter Pylori Infection Treatment
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Esomeprazole|DRUG: Bismuth potassium citrate|DRUG: Metronidazole|DRUG: Clarithromycin|DRUG: Levofloxacin|DRUG: Amoxicillin|DRUG: Tetracycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of 1 or 2 Doses of IPV in Latin American Infants Primed With Bivalent OPV Vaccine
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: Bivalent Oral Polio Vaccine (bOPV)|BIOLOGICAL: Trivalent Oral Polio Vaccine (tOPV)|BIOLOGICAL: Monovalent Oral Polio Vaccine Type 2 (mOPV2)|BIOLOGICAL: Sanofi-Pasteur IPV (Sanofi IPV)|BIOLOGICAL: Glaxo SmithKline IPV (GSK IPV)|BIOLOGICAL: Serum Institute of India IPV (SII IPV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Glucoregulatory Effects of Glucagon-like Peptide-1 Receptor (GLP-1 Receptor) Activation in Participants With Type 2 Diabetes Mellitus (MK-0000-222)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Oxyntomodulin|DRUG: Liraglutide 0.6 mg|DRUG: Liraglutide 1.2 mg|DRUG: Placebo for Oxyntomodulin|DRUG: Placebo for Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT