pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: An Observational Study of Tarceva (Erlotinib) in Routine Daily Clinical Practice as Second Line Treatment in Patients With Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Nonsquamous Nonsmall Cell Neoplasm of Lung
Interventions: DRUG: Erlotinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Efficacy of Micro-Osteoperforations Technique on the Orthodontic Tooth Movement Acceleration in Moderate Mandibular Anterior Crowding Cases Treated With Clear Aligners
Status: RECRUITING
Conditions: Crowding of Anterior Mandibular Teeth
Interventions: DEVICE: Micro-osteoperforations Technique|DEVICE: Active comparater
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib and Ixazomib Citrate in Treating Newly Diagnosed, Relapsed or Refractory Waldenstrom Macroglobulinemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Waldenstrom Macroglobulinemia|Refractory Waldenstrom Macroglobulinemia|Waldenstrom Macroglobulinemia
Interventions: DRUG: Ibrutinib|DRUG: Ixazomib Citrate|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacodynamic Study|OTHER: Pharmacokinetic Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Surgery Plus HIPEC With CO2 in Patients Affected by Gastric Carcinoma.GOETH Study
Status: RECRUITING
Conditions: Stomach Neoplasms
Interventions: PROCEDURE: Surgery plus HIPEC CO2|PROCEDURE: Standard surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Outpatient Pragmatic Platform Study (COPPS) - Camostat Sub-Protocol
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: Camostat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lapatinib Resistance in Patients With Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: lapatinib ditosylate|GENETIC: fluorescence in situ hybridization|GENETIC: gene expression analysis|GENETIC: mutation analysis|GENETIC: polymerase chain reaction|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: cell sorting|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy, Safety, and Tolerability, of EN3835 vs Placebo in the Treatment of Plantar Fibromatosis
Status: COMPLETED
Conditions: Plantar Fibromatosis
Interventions: BIOLOGICAL: EN3835|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Amounts of 2 Different Forms of Tafamidis (PF06291826), Both With and Without Food, In the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: tafamidis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anti-Fatigue Mat For Operating Room Nurses Fatigue And Bottom Of Use And Foot Bath Effect on Extremity Pain
Status: ENROLLING_BY_INVITATION
Conditions: Lower Extremity Pain|Fatigue
Interventions: OTHER: Mat use application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Borg Score Outcomes in Respiratory Compromised Acute Exacerbating Chronic Obstructive Pulmonary Disease (COPD) Patients Receiving Treatment Via Vibrating Mesh Nebuliser Versus Jet Nebuliser in the Emergency Department
Status: UNKNOWN
Conditions: COPD Exacerbation|COPD
Interventions: DEVICE: Jet Nebuliser|DEVICE: Vibrating Mesh Nebuliser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BBI608 Administrated With FOLFIRI + Bevacizumab in Adult Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: BBI608|DRUG: 5-FU|DRUG: Irinotecan|DRUG: Levofolinate|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bispecific CD19/CD22 CAR-T for Treatment of Children and Young Adults With r/r B-ALL
Status: ACTIVE_NOT_RECRUITING
Conditions: B-ALL
Interventions: DRUG: CD19/CD22 CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Positive End-expiratory Pressure Guided by End-expiratory Lung Volume in the Acute Respiratory Distress Syndrome
Status: RECRUITING
Conditions: Respiratory Distress Syndrome, Adult
Interventions: DEVICE: Invasive Mechanical ventilation|DRUG: Neuromuscular Blocking Agents|PROCEDURE: Prone positioning|PROCEDURE: Resume of spontaneous breathing|PROCEDURE: Rescue treatments|PROCEDURE: Weaning from PEEP|PROCEDURE: Weaning from mechanical ventilation|PROCEDURE: Extubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Biomaterials as Desensitizer Agents
Status: UNKNOWN
Conditions: Dentin Sensitivity
Interventions: OTHER: Cavex Bite&White ExSense|OTHER: Kuraray Teethmate™ Desensitizer|OTHER: Ghimas Dentin Desensitizer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Risk of Inhibitor Formation in Previously Treated Patients With Severe Hemophilia A
Status: TERMINATED
Conditions: Hemophilia A
Interventions: DRUG: Kogenate (BAY 14-2222)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Postoperative Physician Phone Calls for Hand and Wrist Fractures
Status: COMPLETED
Conditions: Hand Injuries|Trauma|Hand Injuries and Disorders
Interventions: BEHAVIORAL: Postoperative phone call
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prefrontal Cortical Engagement Through Non-Invasive Brain Stimulation in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Psychosis
Interventions: DEVICE: transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Care-based Program to Enhance Positive Parenting Practices
Status: COMPLETED
Conditions: Parenting|Development|Language|Children
Interventions: BEHAVIORAL: Sit Down and Play|BEHAVIORAL: Handout
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Biomarker Identification Trial of Tarceva (Erlotinib) in Patients With Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Erlotinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Quetiapine Fumarate Tablets 25 mg Under Fasting Condition
Status: COMPLETED
Conditions: Fasting State
Interventions: DRUG: Quetiapine Fumarate Tablets 25 mg|DRUG: Quetiapine Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Repaglinide on Postprandial Lipemia in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: repaglinide|DRUG: glyburide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Encouraging Annual Wellness Visits Among ACO Beneficiaries
Status: COMPLETED
Conditions: Health Promotion|Prevention|Risk Reduction Behavior|Telehealth
Interventions: BEHAVIORAL: Postcard|BEHAVIORAL: Phone call|BEHAVIORAL: Humor/Salience|BEHAVIORAL: Telehealth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TACKLE-IT Trial - Treat Acute T Cell Rejection With Evidence and Confidence in Kidney Transplant Recipients
Status: NOT_YET_RECRUITING
Conditions: Rejection; Transplant, Kidney|Rejection; Transplant, Pancreas
Interventions: DRUG: Methylprednisolone|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methylphenidate and Physical Activity to Reduce Cancer Related Fatigue Due to Anti PD1 Immunotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Neoplasm|Metastatic Malignant Neoplasm|Recurrent Malignant Neoplasm
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Methylphenidate|OTHER: Physical Activity|OTHER: Placebo|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Tetracaine 0.5% and Lidocaine 2% Jelly for Topical Phacoemulsification Cataract Surgery
Status: COMPLETED
Conditions: Cataracts
Interventions: DRUG: tetracaine 0.5%|DRUG: Lidocaine 2% Jelly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Avelumab With Decitabine as First Line for AML Treatment of Patients With AML, Who Are Unfit for Intensive Chemotherapy
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of New Virtual Reality Treatment for Children With Lazy Eye Using the Vedea Amblyopia Therapy (VAT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Amblyopia, Anisometropic|Amblyopia Strabismic|Amblyopia
Interventions: DEVICE: Vedea Amblyopia Therapy (VAT)|DEVICE: Occlusion therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Saturno IIB Association on the Control of Ocular Inflammation Post-phacoemulsification
Status: COMPLETED
Conditions: Ocular Inflammation|Cataract
Interventions: DRUG: SATURNO II association|DRUG: Vigadexa®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing the Safety and Effectiveness of Tunnel PICC Guided by EDUG and Conventional PICC
Status: NOT_YET_RECRUITING
Conditions: the Incidence of PICC-related Complications
Interventions: DEVICE: PICC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Anti-resistance Exercise on Lower Limb Lymphoedema Among Gynecological Cancer
Status: UNKNOWN
Conditions: Gynecological Cancer|Lower Limb Lymphedema
Interventions: BEHAVIORAL: home-based anti-resistance exercise|BEHAVIORAL: usually care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Growth and Nutritional Status of Very Low Birth Weight Infants Fed a High Protein Exclusive Human Milk Diet
Status: UNKNOWN
Conditions: Premature Infant|Breast Milk Expression
Interventions: OTHER: Human milk based human milk fortifier
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of Postprandial Glycemic Responses by Continuous Glucose Monitoring in a Real-World Setting
Status: COMPLETED
Conditions: Postprandial Glucose Response|Glycaemic Index|Continous Glucose Measurement
Interventions: DEVICE: Determination of postprandial glucose response by continuous glucose measurement after consuming different carbohydrate containing foods
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: OxSYPan: Oxford Study With Young People on Antidepressants
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Fluoxetine|OTHER: Peppermint syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Ultratrace™ Iobenguane I 131 in Neuroblastoma
Status: WITHDRAWN
Conditions: Neuroblastoma
Interventions: DRUG: Ultratrace Iobenguane I 131
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study of How a New Medicine NNC0365-3769 (Mim8) Works in the Body of Healthy People
Status: COMPLETED
Conditions: Healthy Volunteers - Haemophilia A
Interventions: DRUG: Mim8 B, 10 mg/mL|DRUG: Mim8 B, 100 mg/mL|DRUG: Mim8 B, placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of PEP'C-R on Endurance Parameters and Maximal Cardio-respiratory Function Among Sedentary Older Seniors Over 70
Status: TERMINATED
Conditions: Sedentary Lifestyle in Patients Over 70
Interventions: OTHER: PEP'C-R|OTHER: Control group usual activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Surviving Aneurysm Surgery: A Pilot Study on Exercise Training in Abdominal Aortic Aneurysm Patients
Status: TERMINATED
Conditions: Abdominal Aortic Aneurysm|Aortic Disease|Vascular Disease|Cardiovascular Disease
Interventions: BEHAVIORAL: Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incremental PD With Single Icodextrin Exchange
Status: NOT_YET_RECRUITING
Conditions: Peritoneal Dialysis Complication|Residual Kidney Function|Survival|Health-related Quality of Life
Interventions: OTHER: Single daily icodextrin exchange|OTHER: Conventional PD group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Robotic Total Knee Arthroplasty Anesthesia Management
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis|Joint Diseases|Anesthesia
Interventions: PROCEDURE: the robot assisted total knee arthroplasty|PROCEDURE: the conventional jig-based total knee arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Inhaled Nitric Oxide on Maximal Oxygen Consumption During Exercise in Hypoxia
Status: COMPLETED
Conditions: Hypoxia
Interventions: DRUG: Nitric Oxide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Closure of Oroantral Fistula (OAF) Using Platelet Rich Fibrin With Middle Meatal Antrostomy
Status: COMPLETED
Conditions: Oroantral Fistula
Interventions: PROCEDURE: closure by PRF membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction of Labor in Pregnant Women With Prelabor Rupture of Membranes - Oxytocin or Misoprostol
Status: COMPLETED
Conditions: Prelabor Rupture of Membranes
Interventions: DRUG: Misoprostol|DRUG: Syntocinon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testosterone Pellets Plus Vitamin D and E Versus Vitamin D and E Alone for the Treatment of Peyronie's Disease
Status: COMPLETED
Conditions: Peyronie's Disease
Interventions: DRUG: Vitamin D2|DRUG: Vitamin E|DRUG: Testosterone Pellets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of AFQ056 in Reducing L-dopa Induced Dyskinesias in Parkinson's Disease Patients, and Safety in Combination With L-dopa
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: AFQ056|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Bailing Capsule on Pulmonary Fibrosis After COVID-19
Status: RECRUITING
Conditions: Pulmonary Fibrosis|COVID-19 Pneumonia
Interventions: DRUG: Bailing capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating the Pharmacokinetics of a Single Dose Administration of Cotadutide
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: COMBINATION_PRODUCT: cotadutide multidose pen injection|COMBINATION_PRODUCT: cotadutide multidose pen injection|COMBINATION_PRODUCT: cotadutide multidose pen injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of IV Nalbuphine on Nausea and Vomiting Following Intrathecal Morphine
Status: NOT_YET_RECRUITING
Conditions: Inguinal Hernia
Interventions: DRUG: nalbuphine on N and V and pain with intrathecal morphine onInguinal hernia repair surgery. randomized, prospective, double blinded and placebo-controlled trial study.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Neuromuscular Fatigue in Chronic Obstructive Pulonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: OTHER: Single then dual task situation|OTHER: Dual then single task situation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Short-Infusion Ziv-aflibercept in Treating Patients With Metastatic Colorectal Cancer Receiving Combination Chemotherapy
Status: WITHDRAWN
Conditions: Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IVA Colon Cancer|Stage IVA Rectal Cancer|Stage IVB Colon Cancer|Stage IVB Rectal Cancer
Interventions: BIOLOGICAL: ziv-aflibercept|DRUG: leucovorin calcium|DRUG: irinotecan hydrochloride|DRUG: fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ranibizumab Supplementing Panretinal Photocoagulation as Treatment for Iris/Angle Neovascularization in Retinal Ischemic Disease
Status: COMPLETED
Conditions: Retinal Ischemia
Interventions: PROCEDURE: Panretinal Photocoagulation|PROCEDURE: Panretinal Photocoagulation and intravitreal injection of ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Augmented Care at Worksite for Diabetes Prevention
Status: COMPLETED
Conditions: PreDiabetes
Interventions: BEHAVIORAL: Group Lifestyle Balance (GLB)|BEHAVIORAL: Group Lifestyle Balance Plus (GLB+)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Modified Periosteal Inhibition With Simultaneous Implant Placement in Aesthetic Zone
Status: RECRUITING
Conditions: Immediate Dental Implant
Interventions: PROCEDURE: Modified periosteal inhibition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Head Rotation on Efficacy of Face Mask Ventilation in Anesthetized Obese (BMI ≥ 35) Adults
Status: COMPLETED
Conditions: Noninvasive Ventilation
Interventions: PROCEDURE: Head Rotation During Face Mask Ventilation|DEVICE: Medline Top Valve Anesthesia Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Guided Discontinuation Versus Maintenance Treatment of Sirolimus in Pediatric Patients With Kaposiform Hemangioendothelioma
Status: COMPLETED
Conditions: Kaposiform Hemangioendothelioma|Kasabach-Merritt Syndrome
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Integrated Interactive Digital Health Application and Telemonitoring in Patients With Heart Failure and Reduced Ejection Fraction
Status: NOT_YET_RECRUITING
Conditions: Heart Failure|Health Behavior
Interventions: BEHAVIORAL: Interactive digital health application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial Comparing Continuous Glucose Monitoring With and Without Routine Blood Glucose Monitoring in Adults With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: CGM+BGM|DEVICE: CGM Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Outcomes of Autologous Bone Marrow-derived Mononuclear Cell Transplantation in the Management of Neurological Sequelae
Status: COMPLETED
Conditions: Sequelae of Injuries of Head
Interventions: BIOLOGICAL: autologous bone marrow-derived mononuclear cell transplantation|OTHER: Rehabilitation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessing Microvascular Resistance Via IMR To Predict Cumulative Outcome in STEMI Patients Undergoing Primary PCI
Status: COMPLETED
Conditions: Multi Vessel Coronary Artery Disease|STEMI
Interventions: DEVICE: PressureWire Certus guidewire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Potential Use of BOLD MRI as a Noninvasive Measure of Tumor Hypoxia in Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: MRI Prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Modeling Multi-level Dyadic Behavior to Transform the Science and Practice of Psychotherapy Process and Outcome.
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Interpersonal Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intravenous Prehydration on the Hemodynamic Status of Healthy Parturients Undergoing Spinal Anesthesia for Cesarean Delivery
Status: COMPLETED
Conditions: Hypotension
Interventions: OTHER: Lactated Ringer's|OTHER: HES 130/0.42
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Controlling Oral Malodor by ClōSYS Oral Rinse
Status: COMPLETED
Conditions: Oral Malodor
Interventions: DRUG: ClōSYS® Unflavored Rinse|DRUG: ClōSYS® Flavored Rinse|OTHER: Placebo-Flavored Oral Rinse|OTHER: Placebo-Unflavored Oral Rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Cognitive, Exposure, and Skills Group Manualized Treatments in Operations Iraqi (OIF)/Operation Enduring Freedom (OEF) Female Veterans
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: 16-Week Group Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PACT (Platelet Activity After Clopidogrel Termination)
Status: COMPLETED
Conditions: Blood Platelets|Clopidogrel
Interventions: DRUG: clopidogrel + aspirin|DRUG: placebo|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Assess the Safety, Tolerability and Pharmacokinetic Properties of Niclosamide Injectable (DWRX2003) Which is the Treatment of COVID-19 in Healthy Volunteers.
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: DWRX2003, 96mg|DRUG: DWRX2003, 432mg|DRUG: DWRX2003, 144mg|DRUG: DWRX2003, 144mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of 120mg Somatuline Autogel at Different Dose Intervals (28, 42 or 56 Days) in Patients With Acromegaly
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: lanreotide (Autogel formulation), duration of treatment 24-56 weeks, depending on dose interval
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Sirolimus in Kidney Transplant Recipients
Status: COMPLETED
Conditions: Graft vs Host Disease|Kidney Transplantation
Interventions: DRUG: sirolimus|DRUG: cyclosporine|DRUG: mycophenolate mofetil|DRUG: corticosteroids|DRUG: daclizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of ALPHAGAN® P and LUMIGAN® in Subjects Previously Treated With Latanoprost for Glaucoma and Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: 0.1% brimonidine tartrate ophthalmic solution|DRUG: 0.01% bimatoprost ophthalmic solution|DRUG: 0.2% hypromellose lubricant eye drops|DRUG: latanoprost 0.005% ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoporative Bevacizumab, Radiation Therapy, and XELOX Chemotherapy for Locally Advanced Nonmetastatic Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: DRUG: Xeloda|DRUG: Oxaliplatin|DRUG: Bevacizumab|RADIATION: Radiation|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Assess the Efficacy and Safety of Amizon® Max in the Treatment of Moderate Covid-19, Caused by the SARS-CoV-2 Virus
Status: COMPLETED
Conditions: Covid-19 Disease
Interventions: DRUG: Enisamium Iodide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of GVHD Prophylasxis With PTCy or Thymoglobulin in Unrelated SCT
Status: TERMINATED
Conditions: Leukemia, Chronic Myeloid|Myelodysplastic Syndromes|Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative
Interventions: PROCEDURE: Unrelated allogeneic stem cell transplantation|DRUG: Busulfan|DRUG: Fludarabine monophosphate|DRUG: Tacrolimus|DRUG: Mycophenolate mofetil|DRUG: Cyclophosphamide|DRUG: Thymoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clavipectoral Fascial Plane Block Versus Superficial Cervical Block in Fracture Clavicle
Status: COMPLETED
Conditions: Fracture Clavicle
Interventions: DIAGNOSTIC_TEST: pain assessment after clavicular fracture repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Using 14-day Continuous Electrocardiography Patch Monitoring to Detect Paroxysmal Atrial Fibrillation After Stroke
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Ischemic Stroke
Interventions: DIAGNOSTIC_TEST: Prolonged ECG monitoring|DIAGNOSTIC_TEST: Conventional procedure group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vagal Nerve Stimulation for the Treatment of Persistent AF
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: Vagal stimulation with the device tVNS from tVNS Technologies GmbH|DEVICE: Sham stimulation with the device tVNS from tVNS Technologies GmbH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Robot-Assisted Gait Training and Conventional Therapy in Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: robot assisted gait therapy|OTHER: Conventional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Angiotensin Converting Enzyme rs (1799752) Gene Polymorphism and Development of In-Stent Restenosis in Patients With Stable Coronary Artery Diseases in Sohag Hospital University.
Status: RECRUITING
Conditions: Angiotensin Converting Enzyme rs (1799752) Gene Polymorphism and Development of In-Stent Restenosis in Patients With Stable Coronary Artery Diseases
Interventions: GENETIC: DNA extraction AND Real- time polymerase chain reaction analysis to POLYMORPHISM OF in in-stent restenosis (ISR) in CAD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Flow Nasal Cannula in Comparison to Apneic Oxygenation During Foreign Body Removal by Rigid Bronchoscope
Status: UNKNOWN
Conditions: Anesthesia
Interventions: DEVICE: Vapotherm|DEVICE: Apneic oxygenation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Postprandial Fatty Acids and FABP2 in Type 2 Diabetes Mellitus (DM)
Status: COMPLETED
Conditions: Dyslipidemia|Type 2 Diabetes Mellitus
Interventions: OTHER: sandwich
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study of the Efficacy and Safety of Topiramate as add-on Therapy in the Treatment of Epilepsy Patients With Difficult to Treat, Partial-onset Seizures.
Status: COMPLETED
Conditions: Epilepsy|Epilepsies, Partial|Seizures
Interventions: DRUG: topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Tazarotene Plus Clindamycin vs. Adapalene Plus Clindamycin in the Treatment of Facial Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Tazarotene 0.1% gel plus clindamycin 1% gel|DRUG: Adapalene 0.1% gel plus clindamycin 1% gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MEDTRUM A7+ TouchCare Insulin Patch Pump (MedInPS)
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DEVICE: Medtrum A7+ insulin Pump|BIOLOGICAL: Lab A1C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Clinical Utility of Antipsychotic Medication Levels in Plasma as Determined by Liquid Chromatography-Tandem Mass Spectrometry
Status: TERMINATED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Aripiprazole|DRUG: Olanzapine|DRUG: Paliperidone|DRUG: Quetiapine|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Imaginary Resisted Exercise Versus Physical Resisted Exercise on Hand Grip Strength in Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Imaginary Resistance Exercises|OTHER: Physical Resisted Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Clinical Activity of Intramuscular Doses of BB-301 Administered to Subjects With Oculopharyngeal Muscular Dystrophy With Dysphagia
Status: RECRUITING
Conditions: Oculopharyngeal Muscular Dystrophy
Interventions: GENETIC: BB-301: Dose escalation phase 1b cohort 1|GENETIC: BB-301: Dose escalation phase 1b cohort 2|GENETIC: BB-301: Dose escalation phase 1b cohort 3|GENETIC: BB-301: Dose expansion phase 2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tracking Peripheral Immune Cell Infiltration of the Brain in Central Inflammatory Disorders Using [Zr-89]Oxinate-4-labeled Leukocytes.
Status: RECRUITING
Conditions: Fibromyalgia|Chronic Fatigue Syndrome|Multiple Sclerosis|Healthy
Interventions: DRUG: [Zr-89]Oxine-labeled leukocytes PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Colonoscopy Screening: Setting Epic Follow-up Times
Status: COMPLETED
Conditions: Concordance Between Colonoscopy Follow up Interval Noted in Patient Letters vs. Electronic Health Record Chart|Colorectal Cancer
Interventions: OTHER: Assistance with implementing Epic Smartlist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Etoposide Plus Radiation Therapy Followed by Combination Chemotherapy in Treating Children With Newly Diagnosed Advanced Medulloblastoma
Status: COMPLETED
Conditions: Brain Tumors|Central Nervous System Tumors
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effect of Desogestrel on Ventilatory Control in Patients With Congenital Central Hypoventilation Syndrome
Status: TERMINATED
Conditions: Congenital Central Hypoventilation Syndrome
Interventions: DRUG: Desogestrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the Use of Regional Anticoagulation With Citrate in Continuous Venovenous Hemofiltration
Status: COMPLETED
Conditions: Kidney Failure, Acute
Interventions: DRUG: trisodium citrate|DRUG: nadroparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Epidural Steroid Injection on Bone Mineral Density in Postmenopausal Women
Status: COMPLETED
Conditions: To Assess the Changes in Markers of Bone Turnover Over a Six Month Period After Epidural Steroid Inject|To Assess the Changes in Bone Mineral Density
Interventions: DRUG: Triamcinilone (kenalog)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness Of MM & Kinesotaping In The Female Patients Of KO To Improve Pain & Functional Mobility RCT
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DIAGNOSTIC_TEST: Mobilization With Movement|DIAGNOSTIC_TEST: Kinesotaping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Warm Saline Irrigation on Bleeding in Mandibular Third Molar Surgery
Status: COMPLETED
Conditions: Surgical Blood Loss|Third Molar
Interventions: PROCEDURE: warm saline irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Subacromial Decompression Versus Subacromial Bursectomy for Patients With Rotator Cuff Tendinosis
Status: UNKNOWN
Conditions: Tendinosis|Shoulder Impingement Syndrome
Interventions: PROCEDURE: Shoulder bursectomy alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Combination Therapy With Camouflage in the Repigmentation of Vitiligo
Status: COMPLETED
Conditions: Vitiligo
Interventions: COMBINATION_PRODUCT: CapulinTM|OTHER: topical applications and NB-UVB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Guided Imagery and Diaphragmatic Breathing Exercise in Pregnant Women With Hyperemesis Gravidarum
Status: NOT_YET_RECRUITING
Conditions: Hyperemesis Gravidarum
Interventions: OTHER: Breathing Exercise Group|OTHER: Guided Imagery Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Primary Preventive Ventricular Tachycardia Ablation In High-Risk Patients Who Receive A Prophylactic Implantable Cardioverter Defibrillator
Status: NOT_YET_RECRUITING
Conditions: Heart Failure
Interventions: PROCEDURE: Prophylactic Catheter-based VT Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Clinical Efficacy of Next Science Wound Gel (NXTSC) in the Healing of Chronic Wounds
Status: COMPLETED
Conditions: Wound Infection
Interventions: DEVICE: NXTSC wound gel|DEVICE: NXTSC wound gel plus Standard of Care|DEVICE: Standard of Care Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development of PHY606 as Adjunct Therapy for Anemia Patients
Status: COMPLETED
Conditions: Anemia|Herbal Interaction
Interventions: DRUG: PHY606
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: New Non-invasive Modalities for Assessing Retinal Structure and Function
Status: RECRUITING
Conditions: Ischemic Optic Neuropathy|Branch Retinal Artery Occlusion|Hemianopia|Leber Hereditary Optic Neuropathy|Acute Zonal Occult Outer Retinopathy
Interventions: DEVICE: LSFG-NAVI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Mogamulizumab + Docetaxel in Subjects With Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: BIOLOGICAL: mogamulizumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cessation Screening Project
Status: ACTIVE_NOT_RECRUITING
Conditions: Nicotine Dependence
Interventions: DRUG: Preparation Varenicline and Standard Duration Varenicline|DRUG: Preparation Varenicline and Extended Duration Varenicline|DRUG: Standard Duration Varenicline|DRUG: Extended Duration Varenicline|DRUG: Preparation Combination NRT and Standard Duration Combination NRT|DRUG: Preparation Combination NRT and Extended Duration Combination NRT|DRUG: Standard Duration Combination NRT|DRUG: Extended Duration Combination NRT|BEHAVIORAL: Intensive Counseling|BEHAVIORAL: Minimal Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate Safety, Tolerability and Efficacy of NFX88 in SCI
Status: COMPLETED
Conditions: Neuropathic Pain|Spinal Cord Injuries
Interventions: DRUG: NFX88 - 1|DRUG: NFX88 - 2|DRUG: NFX88 - 3|DRUG: PLACEBO - 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves
Status: RECRUITING
Conditions: Aortic Valve Insufficiency|Aortic Valve Stenosis
Interventions: DEVICE: SAPIEN X4 THV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric-inspired Regimen Combined With Venetoclax for Adolescent and Adult Patients With de Novo Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: Precursor Cell Lymphoblastic Leukemia-Lymphoma
Interventions: DRUG: Vincristine|DRUG: Daunorubicin|DRUG: Cyclophosphamide|DRUG: Pegaspargase|DRUG: Prednisone|DRUG: Cytarabine|DRUG: 6-mercaptopurine|DRUG: Dexamethasone|DRUG: Methotrexate|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test How Itraconazole Influences the Amount of BI 894416 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Itraconazole|DRUG: BI 894416
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Trans-radial Versus Trans-femoral Percutaneous Coronary Intervention (PCI) Access Site Approach in Patients With Unstable Angina or Myocardial Infarction Managed With an Invasive Strategy
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Percutaneous Coronary Intervention
Interventions: PROCEDURE: Percutaneous Coronary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Hematopoietic Niche and the Role of Inflammation in the Pathophysiology of Cytopenias After CAR-T Cell Therapy: Potential of Therapies Directed to Repair the Bone Marrow Microenvironment
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: BIOLOGICAL: CAR-T cell therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Absorption and Systematic Pharmacokinetics of IDP-123 Lotion in Comparison With Tazorac Cream
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: IDP-123 Lotion|DRUG: Tazorac Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Shock Wave in the Treatment of Trigger Finger
Status: UNKNOWN
Conditions: Trigger Finger
Interventions: DEVICE: Low energy ESWT|DEVICE: High energy ESWT|DEVICE: Sham ESWT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Use of TIPS With Polytetrafluoroethylene(PTFE) Covered Stents in Cirrhotic Patients With Refractory Ascites
Status: RECRUITING
Conditions: Liver Cirrhoses
Interventions: PROCEDURE: TIPS|PROCEDURE: paracentesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of the Nose in Snoring and Sleep Apnea
Status: UNKNOWN
Conditions: Nasal Obstruction|Apnea, Obstructive Sleep
Interventions: DRUG: Xylometazoline|DRUG: placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Exploring the Safety, Tolerability, and Efficacy of a 28 Day Course Followed by an Additional 56 Day Course of Itacitinib in Subjects With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Itacitinib|DRUG: Itacitinib Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperinflation Respiratory Therapies in Cardiac Surgery Patients
Status: RECRUITING
Conditions: Pulmonary Disease|Postoperative Complications
Interventions: DEVICE: EzPAP|DEVICE: Metaneb|DEVICE: Intermittent Positive Pressure Breathing (IPPB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Long Term Safety and Efficacy of Bimekizumab in Subjects With Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Bimekizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Wellbutrin for Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: DRUG: Wellbutrin (bupropion)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Online Psychotherapy for Emotional Reasoning Bias in Public Speaking Anxiety
Status: NOT_YET_RECRUITING
Conditions: Public Speaking Anxiety
Interventions: BEHAVIORAL: Emotional Reasoning bias correction training|BEHAVIORAL: Module of Mindfulness of the Transdiagnostic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT