pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Assessment of 14-3-3 η (Eta) Protein Antibodies in the Serum of Rheumatoid Arthritis Patients and Its Relation to Atherosclerosis.
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DIAGNOSTIC_TEST: 14-3-3 η (eta) protein antibodies in the serum of rheumatoid arthritis patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MARVEL: Mitochondrial Anti-oxidant Therapy to Resolve Inflammation in Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis Flare
Interventions: DIETARY_SUPPLEMENT: MitoQ|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects Of Discharge Education Program On Recovery And Quality Of Life After Cardiac Surgery
Status: RECRUITING
Conditions: Cardiac Surgery, Heart Surgery, Discharge Education, Nursing, Telenursing, m-Health, Quality of Life, Recovery
Interventions: OTHER: Discharge education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Three-chamber-bag Versus Compounded Bag
Status: COMPLETED
Conditions: Parenteral Nutrition for Patients With Proven Insufficient Enteral Resorption
Interventions: DRUG: NuTRIflex Lipid peri|DRUG: compounded monobag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Bermekimab for the Treatment of Adult Participants With Moderate-to-Severe Atopic Dermatitis
Status: TERMINATED
Conditions: Dermatitis, Atopic
Interventions: DRUG: Bermekimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CerviPrep for Applying Topical Gemcitabine to the Cervix in Treating Patients With Primary Endometrial, Cervical, or Ovarian Epithelial Cancer
Status: COMPLETED
Conditions: Cervical Cancer|Endometrial Cancer|Ovarian Cancer
Interventions: DRUG: topical gemcitabine hydrochloride|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy of Methylphenidate, Dextroamphetamine and Placebo in Children Diagnosed With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Methylphenidate|DRUG: Placebo|DRUG: Dextroamphetamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Feasibility Testing of DM-BOOST Intervention.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Diabetes BOOST|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Different Treatment Approaches in Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|Splints|Rigid Taping|Kinesiotape
Interventions: OTHER: Splint and taping methods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Best Approach in Recurrent-Ovarian-Cancer-with Cediranib-Olaparib
Status: UNKNOWN
Conditions: Ovarian Neoplasms
Interventions: DRUG: Paclitaxel|DRUG: Cediranib|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Heel Protector In Intensive Care Units
Status: RECRUITING
Conditions: Pressure Ulcer, Heel|Plantar Flexion Contracture of Tarsometatarsal Joint
Interventions: DEVICE: The Effect Of Heel Protector In Intensive Care Units|DEVICE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Phase I/II Study of Rapcabtagene Autoleucel in CLL, 3L+ DLBCL, ALL and 1L HR LBCL
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma|Diffuse Large B-cell Lymphoma|Acute Lymphoblastic Leukemia|Large B-cell Lymphoma
Interventions: BIOLOGICAL: Rapcabtagene autoleucel single agent|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MB-dNPM1-TCR.1 in Relapsed/Refractory AML
Status: RECRUITING
Conditions: Leukemia, Myeloid, Acute
Interventions: BIOLOGICAL: MB-dNPM1-TCR.1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ursodeoxycholic Acid (UDCA) Added to the DPP-4 Inhibitor in People With Type 2 Diabetes and Chronic Liver Diseases
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus|Chronic Liver Disease
Interventions: DRUG: UDCA|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identifying Wearable Biomarkers to Monitor Dietary Intake
Status: NOT_YET_RECRUITING
Conditions: Energy Intake|Metabolism|Digestion|Wearables|Dietary Intake Assessment|Healthy Volunteers|Blood Glucose
Interventions: OTHER: High Calorie Meal Intervention|OTHER: Low Calorie Meal Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impedance Spectroscopy for Obstetric Anal Sphincter Injuries Detection
Status: COMPLETED
Conditions: Obstetric Anal Sphincter Injury|Delivery Complication|Obstetric Complication
Interventions: DIAGNOSTIC_TEST: Blood and faeces tests|DEVICE: Impedance spectroscopy test|DIAGNOSTIC_TEST: Full gynecological and proctological examination|DIAGNOSTIC_TEST: Transanal ultrasonography|DIAGNOSTIC_TEST: Anorectal manometry|OTHER: Determining the degree of sphincter injury
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of the Safety and Effectiveness of Levofloxacin Compared With Cefaclor in the Treatment of Adults With Chronic Bronchitis Experiencing Rapid Onset of Worsening of Symptoms Caused by Bacteria
Status: COMPLETED
Conditions: Bronchitis|Bronchitis, Chronic
Interventions: DRUG: levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Modified Ketogenic-Mediterranean Diet on Alzheimer's Disease
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Insulin Resistance
Interventions: OTHER: Low-Carbohydrate Diet|OTHER: Low-Fat Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Hypnobirthing Training on Fear, Pain, Satisfaction and, Birth Outcomes
Status: COMPLETED
Conditions: Prenatal Education|Pregnancy Related|Labor Pain
Interventions: OTHER: Standart care|BEHAVIORAL: Hypnobirthig training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: One Versus Two Unit Transfusions in Oncology Patients - The OTTOP Trial: A Randomized Open-label Pragmatic Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Anemia|Oncology
Interventions: OTHER: Units of transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safely and Efficacy of ClinOleic-based Lipid Parenteral Nutrition
Status: UNKNOWN
Conditions: Nutritional Supplement Toxicity
Interventions: DRUG: ClinOleic (Baxter Healthcare, Deerfield, IL, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pioglitazone on Insulin and Glucose Metabolism in Women With Polycystic Ovary Syndrome (PCOS)
Status: TERMINATED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dexmedetomidine to Treat Bariatric Surgery-associated Pain
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Fentanyl|DRUG: Morphine|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liposomal Bupivacaine in One-level Instrumented Posterior Spinal Fusion
Status: RECRUITING
Conditions: Lumbar Spinal Stenosis|Lumbar Disc Herniation|Lumbar Disc Disease|Lumbar Spondylolisthesis
Interventions: DRUG: Liposomal bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy for Locally Advanced Pancreatic Carcinomas (Phase II Trial)
Status: RECRUITING
Conditions: Pancreas Cancer
Interventions: RADIATION: Particle-therapy using protons or carbon ions|DIAGNOSTIC_TEST: Blood sampling|DIAGNOSTIC_TEST: Magnetic resonance imaging|DIAGNOSTIC_TEST: Computertomography|DIAGNOSTIC_TEST: 18-F-FluorDesoxyGlukose Positron Emission Tomography-Computer Tomography (18F-FDG-PET-CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Adipose Derived Stem Cells Versus Platelet Rich Plasma on Follicular Unit Extraction
Status: UNKNOWN
Conditions: Androgenetic Alopecia
Interventions: BIOLOGICAL: Adipose derived stem cells suspention|BIOLOGICAL: Platelet rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effects of AB-205 in Patients With Lymphoma Undergoing Autologous Hematopoietic Cell Transplantation
Status: TERMINATED
Conditions: Hodgkin Lymphoma|Non Hodgkin Lymphoma
Interventions: BIOLOGICAL: AB-205|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Meninigococcal Conjugate Vaccine Containing Serogroups A,C,Y,W and X (MCV5) in Healthy Adults
Status: COMPLETED
Conditions: Meningococcal Vaccines
Interventions: BIOLOGICAL: Adjuvanted MCV-5|BIOLOGICAL: Non-Adjuvanted MCV-5|BIOLOGICAL: Menactra®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis
Status: RECRUITING
Conditions: Graft Vs Host Disease
Interventions: DRUG: Placebo|DRUG: Abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimization of Keverprazan-amoxicilli Dual Therapy for Helicobacter Pylori
Status: NOT_YET_RECRUITING
Conditions: H. Pylori Infection
Interventions: DRUG: Keverprazan|DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Trial of SYNC-T - Immunotherapy for Patients With Advanced/Metastatic Solid Tumors
Status: RECRUITING
Conditions: Metastatic Cancer|Metastatic Breast Cancer|Metastatic Lung Cancer|Solid Tumor|Cancer
Interventions: DRUG: SV-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET Imaging Study to Evaluate the mGlu5r Occupancy Following ADX48621 (Dipraglurant) Administration
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ADX48621|RADIATION: [18F]FPEB
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Hearing and Structure Preservation Via ECochG
Status: RECRUITING
Conditions: Hearing Loss, Sensorineural|Severe-to-profound Hearing Loss
Interventions: PROCEDURE: ECochG monitored CI surgery incl. corrective action guide|PROCEDURE: Routine CI surgery without ECochG monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Transverse Abdominis Plane Block in Laparoscopic Ventral Hernia Repair
Status: COMPLETED
Conditions: Ventral Hernia
Interventions: PROCEDURE: Laparoscopic ventral hernia repair with TAP block|PROCEDURE: Laparoscopic ventral hernia repair without TAP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Inspiratory Muscle Training on Breathing Pattern in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Muscle Weakness Conditions
Interventions: PROCEDURE: Inspiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A PK/PD Genetic Variation Treatment Algorithm Versus Treatment As Usual for Adolescent Management Of Depression
Status: COMPLETED
Conditions: Depression
Interventions: OTHER: AssureRx GeneSight genotyping results|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quantifying Abnormalities in Cortical Activation Associated With Auditory Hallucinations Using Functional Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Hallucinations
Interventions: DEVICE: functional magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Masitinib in the Treatment of Patients With Severe Uncontrolled Asthma and Elevated Eosinophil Levels
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Masitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: WEAR (Wearability and Evaluation of Adjustable Refraction) III
Status: COMPLETED
Conditions: Myopia
Interventions: OTHER: Adjustable glasses|OTHER: Custom standard glasses|OTHER: Ready-made glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Resveratrol and Midazolam Metabolism
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Midazolam|DIETARY_SUPPLEMENT: resveratrol (single dose)|DIETARY_SUPPLEMENT: resveratrol (multiple dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sitravatinib and Nivolumab in Treating Patients With Advanced or Metastatic Kidney Cancer
Status: COMPLETED
Conditions: Clear Cell Renal Cell Carcinoma|Metastatic Kidney Carcinoma|Stage III Renal Cell Cancer AJCC v7|Stage IV Renal Cell Cancer AJCC v7
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Sitravatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcatheter Mitral Valve Replacement System (TMVR) Pilot Study and The Early Feasibility Study of the TMVR Transseptal System
Status: ACTIVE_NOT_RECRUITING
Conditions: Mitral Valve Insufficiency
Interventions: DEVICE: Twelve TMVR Implant|DEVICE: Medtronic Intrepid™ Transcatheter Transfemoral Mitral Valve Replacement System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of XL092 + Atezolizumab vs Regorafenib in Subjects With Metastatic Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: XL092|DRUG: Atezolizumab|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SPironolactONe for the Maintenance of Sinus Rhythm in Patients With Atrial Fibrillation
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation Recurrent
Interventions: DRUG: Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Administration Using STAR Particles
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: DEVICE: LET Gel after STAR Particle Application (Right or Left Arm)|OTHER: LET Gel Application without STAR Particle Application (Contralateral Arm)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Randomized Study of the Effects of Growth Hormone on Children and Adolescents on Maintenance Dialysis
Status: COMPLETED
Conditions: Renal Osteodystrophy|End Stage Renal Disease
Interventions: DRUG: calcitriol|DRUG: growth hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Nutrition and Body Composition in Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Precursor Cell Lymphoblastic Leukemia-Lymphoma|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D and Calcium Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transcutaneous Vagus Nerve Stimulation (tcVNS) in JIA
Status: ACTIVE_NOT_RECRUITING
Conditions: Juvenile Idiopathic Arthritis (JIA)
Interventions: DEVICE: Active tcVNS or Sham tcVNS|DEVICE: Active tcVNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Training on the Side Effects of Chemotherapy Given Via the Mobile Health Application on the Quality of Life in Colorectal Cancer Patients
Status: RECRUITING
Conditions: Colorectal Cancer|Mobile Phone Use|Nurse's Role
Interventions: OTHER: Colorectal-Mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ketamine Versus Low Dose Thiopental for Induction of Anesthesia in Septic Shock
Status: COMPLETED
Conditions: Septic Shock
Interventions: DRUG: Ketamine|DRUG: Thiopental
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Extended Treatment With Firibastat in Treatment-Resistant Hypertension (REFRESH)
Status: TERMINATED
Conditions: Hypertension (HTN)
Interventions: DRUG: Firibastat (QGC001) Period 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Delta-THC in Behavioral Disturbances in Dementia
Status: COMPLETED
Conditions: Dementia
Interventions: DRUG: Delta-THC|DRUG: placebo|DRUG: Delta-THC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Solitaire to Embotrap to Treat Large Vessel Occlusion in Acute Ischemic Stroke (SOLTRAP Study)
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DEVICE: Stent Retrievers|DEVICE: Stent Retriever
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immune Modulators for Treating COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Infliximab|DRUG: Abatacept|DRUG: Remdesivir|DRUG: cenicriviroc (closed to enrollment as of 3-Sep-2021)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability Study of AVP-923 (Dextromethorphan/Quinidine) for Treatment of Symptoms of Agitation in Participants With Alzheimer's Disease
Status: COMPLETED
Conditions: Agitation|Alzheimer's Disease
Interventions: DRUG: AVP-923-20|DRUG: Placebo|DRUG: AVP-923-30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Pantheris System, an Atherectomy Device That Provides Imaging While Removing Plaque in Lower Extremity Arteries
Status: WITHDRAWN
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Pantheris Atherectomy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Patients With the Obstructive Sleep Apnea Syndrome at Altitude
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DRUG: acetazolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MT2022-60: Ph 2 Study of Pembro+ BEAM With ASCT for Relapsed Hodgkin Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Autologous Stem Cell Transplant|Classic Hodgkin Lymphoma
Interventions: DRUG: Pembrolizumab|PROCEDURE: Autologous stem cell transplant|DRUG: Carmustine|DRUG: Etoposide|DRUG: Cytarabine|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This SCR-103 Protocol Will Permit Sites to Proactively Assess TAA, HLA and HPV-16 Status in Patients With Selected Solid Tumors to Determine Suitability for Repertoire Immune Medicines Treatment Protocols.
Status: TERMINATED
Conditions: Head and Neck Cancer|Melanoma|HPV-Related Malignancy|HPV-Related Carcinoma|HPV-Related Cervical Carcinoma|HPV Positive Oropharyngeal Squamous Cell Carcinoma|Lung Cancer, Nonsmall Cell|Melanoma (Skin)
Interventions: DIAGNOSTIC_TEST: Tumor Profiling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating Safety, Tolerability and Pharmacokinetics (PK) of Tarlatamab in Adults With Small Cell Lung Cancer (SCLC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: Tarlatamab|DRUG: Pembrolizumab|DRUG: CRS Mitigation Strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alpha Lipoic Acid and Diabetes Mellitus: Potential Effects on Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Polyneuropathy|Diabetes Mellitus, Type 2
Interventions: DRUG: Alpha lipoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Anesthetic Managements of Esophageal Resection and Reconstruction
Status: UNKNOWN
Conditions: Anesthesia|Esophagus Cancer|Postoperative Complications
Interventions: OTHER: Cardiac Output Maximization|OTHER: Cardiac Output Normalization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 18F-TFB PET/CT Scan in Patients With Differentiated Thyroid Cancer
Status: RECRUITING
Conditions: Differentiated Thyroid Gland Carcinoma|Thyroid Gland Follicular Carcinoma|Thyroid Gland Papillary Carcinoma
Interventions: PROCEDURE: Computed Tomography|RADIATION: Fluorine F 18 Tetrafluoroborate|PROCEDURE: Positron Emission Tomography|OTHER: Survey Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Liraglutide in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Liraglutide 1.8mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carrilizumab Combined With White Purple for Squamous Cell Carcinoma of Skin
Status: RECRUITING
Conditions: Squamous Cell Carcinoma of the Skin
Interventions: DRUG: Carrilizumab with albumin-binding paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of CD19-directed Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ Leukemia
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia, in Relapse|Acute Lymphoblastic Leukemia, Refractory|Pediatric ALL
Interventions: BIOLOGICAL: CD19-CAR(Mem) T-cells|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Mesna|DEVICE: CliniMACS|PROCEDURE: Leukapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of PRO-118 Compared With Olopatadine Hydrochloride Ophthalmic Solution in Allergic Conjunctivitis
Status: WITHDRAWN
Conditions: Allergic Conjunctivitis
Interventions: DRUG: PRO-118|DRUG: Olopatadine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Physical Rehabilitation Program Using the Nintendo Wii on Children With Osteogenesis Imperfecta (OI)
Status: TERMINATED
Conditions: Osteogenesis Imperfecta
Interventions: OTHER: Training with Nintendo Wii console
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Understanding the Immune Response to Meningitis Vaccines
Status: COMPLETED
Conditions: Meningitis|Septicemia
Interventions: BIOLOGICAL: Meningococcal (Groups A, C, Y and W-135) Conjugate|BIOLOGICAL: Meningococcal polysaccharide A, C, Y and W135 and Menveo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: HEM iSMART-D: Trametinib + Dexamethasone + Chemotherapy in Children With Relapsed or Refractory Hematological Malignancies
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia, in Relapse|Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent|Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent|Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory|Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory
Interventions: DRUG: Trametinib|DRUG: Dexamethasone|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Intrathecal chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neutralizing Antibody Seroprevalence Study With a Retrospective Component in Participants With Late-Onset Pompe Disease
Status: COMPLETED
Conditions: Pompe Disease|Pompe Disease (Late-onset)|Glycogen Storage Disease Type 2|LOPD|Lysosomal Storage Diseases|Acid Maltase Deficiency
Interventions: DIAGNOSTIC_TEST: Neutralizing Antibody to SPK-3006 capsid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Pulmonary Endarterectomy Guided by CT Scanning for Patients With Chronic Thromboembolic Pulmonary Hypertension----PEACT
Status: UNKNOWN
Conditions: Chronic Thromboembolic Pulmonary Hypertension|Pulmonary Embolism
Interventions: DIAGNOSTIC_TEST: 3-D CT scanning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epirubicin and Tamoxifen With or Without Docetaxel in Treating Postmenopausal Women With Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: docetaxel|DRUG: epirubicin hydrochloride|DRUG: tamoxifen citrate|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: LAAO Versus NOAC in Patients With AF and PCI
Status: RECRUITING
Conditions: Atrial Fibrillation|Percutaneous Coronary Intervention
Interventions: DEVICE: The WATCHMAN/WATCHMAN FLX device|DRUG: Rivaroxaban + Clopidogre|DRUG: Aspirin + Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Liraglutide on Epicardial Fat in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Overweight|Obesity
Interventions: DRUG: Liraglutide|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First in Human Evaluation of a Novel Approach to Painless Cardioversion (NAPC) in Patients With Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: OTHER: Cool therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Study of Torrent Pharmaceutical Limited's Donepezil Hydrochloride Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Torrent's Donepezil Hydrochloride Tablets 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: SUperior Hypogastric Plexus Block During Laparoscopic hysterEctomy (SUBTLE)
Status: NOT_YET_RECRUITING
Conditions: Hysterectomy
Interventions: PROCEDURE: Superior hypogastric plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of Two Oral Haloperidol Tablets Formulations in Healthy Subjects Under Fasting Conditions
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Haloperidol Tablets, Mylan Pharmaceuticals Inc.|DRUG: Haloperidol Tablets, Cycle Pharmaceuticals Ltd
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Endoscopy and Diffusion-weighted Enterography-MRI for the Diagnosis of Crohn's Disease Recurrence Following Ileocolic Resection: a Pilot Study
Status: UNKNOWN
Conditions: Crohn's Disease
Interventions: OTHER: MRI enterography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Two NN1250 Formulations Versus Insulin Glargine, All in Combination With Insulin Aspart in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec|DRUG: insulin degludec|DRUG: insulin glargine|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of TEG 6S PM® During Cardiopulmonary Bypass to Detect Postoperative Biological Coagulopathy
Status: NOT_YET_RECRUITING
Conditions: Coagulopathy|Cardiopulmonary Bypass|Cardiac Surgery
Interventions: DIAGNOSTIC_TEST: In vitro medical diagnostic device TEG6s® Platelet Mapping
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Refining Treatment Options for Trichomonas Vaginalis Infection: A Comparative Analysis of Metronidazole and Secnidazole
Status: NOT_YET_RECRUITING
Conditions: Trichomonas Vaginitis
Interventions: DRUG: Metronidazole 500 mg|DRUG: Secnidazole 2000 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nebulized 3% Hypertonic Saline in the Treatment of Acute Bronchiolitis
Status: COMPLETED
Conditions: Acute Bronchiolitis
Interventions: DRUG: 3% Hypertonic Saline|DRUG: 0.9 % normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immune Globulin Intravenous (IGIV) For Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Status: COMPLETED
Conditions: Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Interventions: DRUG: Immune Globulin IV (Human), 10% Caprylate/Chromatography Purified|DRUG: Albumin (Human) 25%, United States Pharmacopeia (USP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EC-18 for Oral Mucositis in Patients With Concomitant Chemoirradiation
Status: COMPLETED
Conditions: Stomatitis
Interventions: DRUG: EC-18|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Skin Hydration in Persons With Acne After Dietary Supplementation With Botanical Antioxidants
Status: WITHDRAWN
Conditions: Acne Vulgaris|Acne
Interventions: DIETARY_SUPPLEMENT: HBKB Capsule|OTHER: HBKB Supplement Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Zinc Supplementation In Very Low Birth Weight Infants-A Randomised Controlled Trial
Status: COMPLETED
Conditions: Preterm Infant|Effect of Drugs|Zinc Deficiency Disease
Interventions: DRUG: Zinc Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Late LTP-like Plasticity Effects of tDCS in Chronic Stroke Patients
Status: COMPLETED
Conditions: Stroke|Hemiparesis
Interventions: DEVICE: Sham|DEVICE: Conventional Paired tDCS|DEVICE: Conventional Unpaired tDCS|DEVICE: Late LTP-like Plasticity tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxygen Therapy in Children and Adolescents With Down Syndrome and Obstructive Sleep Apnea
Status: RECRUITING
Conditions: Down Syndrome|Obstructive Sleep Apnea
Interventions: DRUG: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET/CT Changes During Chemoimmunotherapy and Radiation Therapy in Patients With Stage IV Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Metastatic Lung Non-Small Cell Carcinoma|Recurrent Lung Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8
Interventions: PROCEDURE: Positron Emission Tomography|PROCEDURE: Computed Tomography|DRUG: Chemotherapy|BIOLOGICAL: Immunotherapy|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Feedback Health Education on Postoperative Rehabilitation of Patients With Lumbar Disc Herniation
Status: COMPLETED
Conditions: Lumbar Disc Herniation
Interventions: BEHAVIORAL: Feedback-based health education|BEHAVIORAL: Routine health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Naldemedine in Treating Opioid-induced Constipation
Status: COMPLETED
Conditions: Opioid-induced Constipation
Interventions: DRUG: Naldemedine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study Looking at How the Medicine NNC0385-0434 Works in the Body of Healthy Japanese Men
Status: COMPLETED
Conditions: Healthy Volunteers|Atherosclerotic Cardiovascular Disease
Interventions: DRUG: NNC0385-0434|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization
Status: RECRUITING
Conditions: AAA|AAA - Abdominal Aortic Aneurysm
Interventions: DEVICE: Alto Abdominal Stent Graft System|DEVICE: FDA Approved EVAR AAA Graft Systems
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of Continuous Oral Treatment With BIBF 1120 Added to Standard Gemcitabine/Cisplatin Therapy in First Line NSCLC Patients With Squamous Cell Histology.
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: BIBF 1120|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Rivaroxaban vs Warfarin for SPAF in Multi-morbid Patients
Status: COMPLETED
Conditions: Nonvalvular Atrial Fibrillation
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Vitamin K antagonist (VKA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Smart Phone Application Supported Nursing Care Program
Status: UNKNOWN
Conditions: Hypertension
Interventions: BEHAVIORAL: Health belief model-based smartphone-assisted nursing care program application will be installed on the phones of the patients who will be in the intervention group.|BEHAVIORAL: Standart care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lifestyle Modification Using an App in OSA
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Obesity
Interventions: BEHAVIORAL: Life style modification by using and app with a wrist-worn activity tracker|BEHAVIORAL: Conventional Life style modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of IVIG-L in ITP Patients
Status: COMPLETED
Conditions: Purpura, Thrombocytopenic, Idiopathic
Interventions: DRUG: IVIG-L
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Nilotinib With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia (CML)
Status: COMPLETED
Conditions: Leukemia, Myelogenous, Chronic
Interventions: DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proteomic and Metabolomic Lacrimal Fingerprint in Diverse Pathologies of the Ocular Surface
Status: RECRUITING
Conditions: Dry Eye Syndrome|Infectious Keratoconjunctivitis|Mucous Membrane Pemphigoid|Allergic Conjunctivitis
Interventions: DIAGNOSTIC_TEST: Tear sample collection via Schirmer strip and subsequent analysis by mass spectrometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Psychoeducational Intervention Supporting Patients With an Inherited Cardiac Condition
Status: SUSPENDED
Conditions: Inherited Cardiac Conduction Disorder|Cardiomyopathies
Interventions: BEHAVIORAL: PISICC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Study With the Trifunctional Antibody Ertumaxomab to Treat Metastatic Breast Cancer Progressing After Endocrine Treatment
Status: TERMINATED
Conditions: Metastatic Breast Cancer|Advanced Breast Cancer
Interventions: BIOLOGICAL: ertumaxomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vibrotactile Feedback Belt in Patients With Unilateral Vestibular Hypofunction (UVH)
Status: NOT_YET_RECRUITING
Conditions: Vestibular Disorder
Interventions: DEVICE: BalanceBelt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Group Walking Sessions for Increasing Activity in People With Peripheral Arterial Disease (The Group Oriented Arterial Leg Study [GOALS])
Status: COMPLETED
Conditions: Peripheral Vascular Diseases|Cardiovascular Diseases
Interventions: BEHAVIORAL: Group mediated cognitive behavioral (GMCB) sessions|OTHER: Health education sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 3D Tablet Sensor Approach to the Measurement of a Lymphedema
Status: RECRUITING
Conditions: Lymphedema
Interventions: DEVICE: Water displacement volumetry|DEVICE: Three dimension volumetry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Adapting a Brief Suicide Intervention for Pediatric Primary Care: Enhancing Uptake and Impact
Status: NOT_YET_RECRUITING
Conditions: Suicide Prevention
Interventions: BEHAVIORAL: Adapted SAFETY-A for PC|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study To Assess the Pharmacokinetics of AZD1656 During Coadministration With Simvastatin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: AZD1656|DRUG: simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Symptom Screening With Targeted Early Palliative Care (STEP) for Patients With Advanced Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: Symptom screening with Targeted Early Palliative care (STEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Real World Registry for Use of the Ion Endoluminal System
Status: RECRUITING
Conditions: Lung Cancer|Multiple Pulmonary Nodules|Lung Neoplasms|Respiratory Tract Neoplasms|Thoracic Neoplasms|Neoplasms by Site|Neoplasms|Lung Diseases|Respiratory Tract Diseases
Interventions: DEVICE: Ion Endoluminal System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dextromethorphan in Treating Patients With Fatigue Caused by Cancer
Status: TERMINATED
Conditions: Fatigue|Unspecified Adult Solid Tumor, Protocol Specific|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: dextromethorphan hydrobromide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Effects of RCN3028 on Moderate to Severe Vasomotor Symptoms in Women
Status: COMPLETED
Conditions: PMS|Hot Flashes
Interventions: DRUG: I placebo capsule|DRUG: II RDC 0.3mg capsule|DRUG: III RDC 0.6mg capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cross-over Study to Prove Bioequivalence Between Two Brands of Cefalexin Suspension
Status: COMPLETED
Conditions: Anti-Infective Agents
Interventions: DRUG: Cephalexin suspension (Optocef, BAYO5448)|DRUG: Cephalexin suspension (Keflex)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study for Patients With Newly Diagnosed, High-risk Acute Promyelocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Promyelocytic Leukemia
Interventions: DRUG: Arsenic trioxide|DRUG: Idarubicin|DRUG: Cytarabine|DRUG: Tretinoin|DRUG: Mitoxantrone|DRUG: Mercaptopurine|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study Evaluating the Effect of Repository Corticotropin in the Treatment of Various Nephrotic Syndromes
Status: COMPLETED
Conditions: Nephrotic Syndromes
Interventions: DRUG: Repository corticotrophin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Certolizumab Pegol (CZP) Versus Active Comparator and Placebo in Subjects With Plaque Psoriasis (PSO)
Status: COMPLETED
Conditions: Psoriasis|Plaque Psoriasis
Interventions: BIOLOGICAL: Certolizumab Pegol|BIOLOGICAL: Etanercept|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Virtual Reality Devices in People With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DEVICE: Cerebral Palsy - Kinect|DEVICE: Cerebral Palsy - Touchscreen|DEVICE: Control Group - Kinect|DEVICE: Control Group - Touchscreen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER