pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Argatroban for Preventing Occlusion and Restenosis After Extracranial Vertebral Artery Stenting
Status: COMPLETED
Conditions: CVD
Interventions: DRUG: Argatroban|DRUG: non-argatroban treated group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Smokers With Mental Illness
Status: COMPLETED
Conditions: Smoking Cessation|Cigarette Smoking|Schizophrenia|Psychotic Disorders|Major Depressive Disorder|Bipolar Disorder I|Bipolar II Disorder|Mental Illness
Interventions: DRUG: Nicotine patch|DRUG: Nicotine lozenge|BEHAVIORAL: Therapy|OTHER: Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Rehabilitation of Working Memory After Moderate to Severe Traumatic Brain Injury
Status: RECRUITING
Conditions: Moderate to Severe Traumatic Brain Injury
Interventions: OTHER: Specific rehabilitation|OTHER: Non-specific rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy Of Ultrasound-Guided Adductor Canal Block for Arthroscopic Knee Surgery
Status: COMPLETED
Conditions: Knee Arthropathy
Interventions: OTHER: Group Preoperatively Adductor Canal Block|OTHER: Group Preoperatively Tourniquet Adductor Canal Block|OTHER: Group Postoperatively Adductor Canal Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Crestor on Inflammation of Atherosclerotic Plaques
Status: COMPLETED
Conditions: Atherosclerosis|Inflammatory Activity in Carotid Arteries
Interventions: DRUG: rosuvastatin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Motivation and Skills for Detained Teen Smokers
Status: COMPLETED
Conditions: Motivational Intervention|Nicotine Anonymous|Cognitive Behavior Therapy|Relaxation Therapy
Interventions: BEHAVIORAL: Motivational Intervention|BEHAVIORAL: Relaxation Therapy|BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Self-Help Programming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Anamorelin Hydrochloride in Reducing Anorexia in Patients With Advanced Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Anorexia|Lung Non-Small Cell Carcinoma|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: DRUG: Anamorelin Hydrochloride|OTHER: Placebo|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pain Management Following Dental Treatment Under General Anesthesia
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ibuprofen 200 mg|DRUG: paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Intragastric Fatty Acid Infusion on Behavioral Responses to Positive Emotion Induction in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Dodecanoic acid|BEHAVIORAL: Positive emotion|DIETARY_SUPPLEMENT: saline|BEHAVIORAL: neutral emotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Carboplatin Plus Etoposide With or Without ZKAB001 (Anti-PD-L1 Antibody) in Patients With ES-SCLC
Status: COMPLETED
Conditions: Extensive-stage Small-cell Lung Cancer
Interventions: BIOLOGICAL: ZKAB001|DRUG: Placebo|DRUG: Carboplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Predictors of Respiratory Syncytial Virus (RSV) Hospitalizations in Infants
Status: UNKNOWN
Conditions: Syncytial Virus Respiratory Infection|RSV Infection|Respiratory Syncytial Virus Infections|RSV Bronchiolitis
Interventions: OTHER: Not applicable (no intervention)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Testing a Behavioural Approach to Improving Cancer Screening Rates
Status: COMPLETED
Conditions: Early Detection of Cancer|Clinical Trial
Interventions: BEHAVIORAL: Anticipated regret|BEHAVIORAL: Material incentive|BEHAVIORAL: Problem solving
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Promoting Seniors' Health With Home Care Aides
Status: COMPLETED
Conditions: Muscle Weakness
Interventions: BEHAVIORAL: Healthy Moves for Aging Well (Healthy Moves)|BEHAVIORAL: Active Mind for Aging Well (Active Mind)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PET Imaging of Peripheral Benzodiazepine Receptors in Patients With Neurocysticercosis Using [C-11]PBR28
Status: COMPLETED
Conditions: Neurocysticercosis|Healthy
Interventions: DRUG: [C-11]PBR28
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Lithium Carbonate on Low-Dose Radioiodine Therapy in Early Thyroid Cancer
Status: COMPLETED
Conditions: Thyroid Cancer|Differentiated Thyroid Carcinoma
Interventions: DRUG: Lithium Carbonate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CRyo-Ablation to Treat Patients With HOCM.
Status: UNKNOWN
Conditions: HOCM, Hypertrophic Obstructive Cardiomyopathy
Interventions: PROCEDURE: CRyo-Ablation to Treat HOCM.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AK104/Placebo Combined With Chemoradiotherapy For The Treatment of Locally Advanced Cervical Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Cervical Carcinoma
Interventions: DRUG: AK104|RADIATION: EBRT|RADIATION: BT|DRUG: cisplatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide, Docetaxel, and Carboplatin in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: carboplatin|DRUG: docetaxel|DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cost-utility and Biological Underpinnings of MBSR in Fibromyalgia Syndrome
Status: COMPLETED
Conditions: Fibromyalgia Syndrome
Interventions: BEHAVIORAL: MBSR|BEHAVIORAL: FibroQol|DRUG: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label, Safety and Superior Effectiveness Study of Cysteamine Bitartrate Delayed-Release Capsules (RP103) in Cystinosis
Status: COMPLETED
Conditions: Cystinosis
Interventions: DRUG: RP103|DRUG: Cystagon®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Taping Methods in Myofascial Pain Syndrome
Status: COMPLETED
Conditions: Myofascial Pain Syndrome|Trigger Point Pain, Myofascial
Interventions: OTHER: Functional Correction Technique|OTHER: Fascia Correction Technique|OTHER: Star Taping Technique|OTHER: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of the Safety and Efficacy of Topical 1-(S)-(3-Hydroxy-2-Phosphonylmethoxypropyl)Cytosine Dihydrate (Cidofovir; HPMPC) in the Treatment of Refractory Mucocutaneous Herpes Simplex Disease in Patients With AIDS
Status: COMPLETED
Conditions: Herpes Simplex|HIV Infections
Interventions: DRUG: Cidofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Temporal Muscle Suspension of Temporal Hollowing
Status: WITHDRAWN
Conditions: Temporal Wasting
Interventions: PROCEDURE: Re-Suspension of the temporal muscle after a craniotomy.|PROCEDURE: Traditional re-suspension of the temporal muscle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Bone Marrow Cell Concentrate Prepared Using the Magellan System to Treat Critical Limb Ischemia (CLI)
Status: COMPLETED
Conditions: Critical Limb Ischemia (CLI)|Peripheral Vascular Disease (PVD)
Interventions: DEVICE: Magellan®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3D-HD Optic Systems Influence Surgical Performance
Status: UNKNOWN
Conditions: Operative Time|Fatigue|Surgery--Complications
Interventions: DEVICE: 3D Optic System (Olympus VISERA Elite II 3D)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: SpO2 Accuracy Comparison of Smart Sock V. 2 SpO2 to Arterial Blood CO-Oximetry
Status: COMPLETED
Conditions: Hypoxia
Interventions: DIAGNOSTIC_TEST: Pulse oximetry with Owlet BabySat v1.0 sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Balloon-Assisted Maturation of Autogenous Arteriovenous Fistulae
Status: COMPLETED
Conditions: Hemodialysis Access Failure
Interventions: PROCEDURE: Balloon Assisted Maturation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Long-term, High-dose N-acetylcysteine on Exacerbations of Bronchiectaisis
Status: COMPLETED
Conditions: Non-Cystic Fibrosis Bronchiectasis
Interventions: DRUG: N-acetylcysteine|OTHER: On-demand treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Hyaluronic Acid in Prevention of Acute Radiation Proctitis
Status: RECRUITING
Conditions: Acute Radiation Proctitis|Acute Radiation Enteritis
Interventions: DRUG: Hyaluronic Acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Long-Term, Follow-Up Study Of the Safety And Efficacy Of Levetiracetam In Children With Partial Onset Seizures
Status: COMPLETED
Conditions: Epilepsy, Partial
Interventions: DRUG: levetiracetam (LEV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Biodesign® Otologic Graft in Tympanoplasty
Status: WITHDRAWN
Conditions: Tympanic Membrane Perforation
Interventions: BIOLOGICAL: Biodesign Otologic graft|OTHER: Autologous temporalis fascia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Reduction of Cardiovascular Risk
Status: COMPLETED
Conditions: Cholesterol
Interventions: DIETARY_SUPPLEMENT: Apigenin, luteonin, grapefruit extract and citrolive|DIETARY_SUPPLEMENT: maltodextrina
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: StEnt Coverage and Neointimal Tissue Characterization After eXtra Long evErolimus - Eluting Stent imPlantation
Status: UNKNOWN
Conditions: Ischemic Heart Disease|Coronary Artery Disease|Coronary Atherosclerosis
Interventions: DEVICE: SYNERGY 48 mm|PROCEDURE: PCI|PROCEDURE: 3 month OCT follow-up|PROCEDURE: 6 month OCT follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotics, Microbiology and Immunology in Children With Chronic Wet Cough - the AMIC Study
Status: RECRUITING
Conditions: Protracted Bacterial Bronchitis
Interventions: DRUG: Amoxicillin-Clavulanate 400 Mg-57 Mg/5 mL Oral Powder for Reconstitution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MIndfulness for Students
Status: UNKNOWN
Conditions: Well-being|Functional Ability|Stress|Mindfulness
Interventions: BEHAVIORAL: Face-to-face group-based mindfulness|BEHAVIORAL: Internet-based mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy Combined With Irinotecan and Apatinib Followed by PD-1 Antibody and Apatinib for Advanced Solid Tumors
Status: UNKNOWN
Conditions: Solid Tumor
Interventions: RADIATION: radiotherapy|DRUG: irinotecan liposome|DRUG: apatinib|DRUG: PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of STYLAGE® L Lidocaïne in the Treatment of Nasolabial Folds
Status: COMPLETED
Conditions: Aging
Interventions: DEVICE: STYLAGE® L Lidocaine|DEVICE: Active control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency and Tolerance of Rituximab (mabthéra) in Bullous Pemphigoid
Status: COMPLETED
Conditions: Bullous Pemphigoid
Interventions: DRUG: Mabthera
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Active Approach to Treat Amblyopia: Video Game Play
Status: COMPLETED
Conditions: Amblyopia
Interventions: BEHAVIORAL: Perceptual learning|BEHAVIORAL: Video Game|BEHAVIORAL: Crossover (Occlusion therapy + Video Game)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transdermal Testosterone Nanoemulsion in Women Libido
Status: UNKNOWN
Conditions: Menopause
Interventions: DRUG: Testosterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Outcome of Short Implant Assisted Mandibular Overdenture
Status: UNKNOWN
Conditions: Atrophy of Edentulous Mandibular Alveolar Ridge
Interventions: COMBINATION_PRODUCT: Two short implants and 2 minutes LLLT|COMBINATION_PRODUCT: Two short implants and 4 minutes LLLT|COMBINATION_PRODUCT: Four short implants and 2 minutes LLLT|COMBINATION_PRODUCT: Four short implants and 4 minutes LLLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Bone Marrow Stem Cell Transplantation for Critical, Limb-threatening Ischemia
Status: UNKNOWN
Conditions: Peripheral Vascular Disease|Diabetic Foot|Peripheral Arterial Occlusive Disease|Leg Ulcer|Gangrene|Ischemia
Interventions: PROCEDURE: Autologous bone marrow cell concentrate transplantation|BIOLOGICAL: saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amniotic Umbilical Cord Particulate During Total Knee Arthroplasty
Status: WITHDRAWN
Conditions: Osteoarthritis: Joint Replacement Surgery
Interventions: OTHER: CLARIX FLO|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Role of Proprioceptive Deficits and Psychosocial Factors in Pregnancy-related Pelvic Girdle Pain: a Follow-up Study
Status: RECRUITING
Conditions: Pelvic Girdle Pain|Low Back Pain
Interventions: BEHAVIORAL: Assessment of postural control, body perception and psychosocial factors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Vagus Nerve Stimulation on Temporomandibular Joint Dysfunction
Status: COMPLETED
Conditions: Temporomandibular Joint Dysfunction Syndrome|Autonomic Nervous System Imbalance
Interventions: OTHER: Auricular Non-Invazive Vagus Nerve Stimulation + Traditional Rehabilitation Program for TMD|OTHER: Traditional Rehabilitation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ARAT for Reflux Disease After Peroral Endoscopic Myotomy in Patients With Achalasia
Status: UNKNOWN
Conditions: Achalasia|Gastroesophageal Reflux
Interventions: PROCEDURE: ARAT technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lebrikizumab (LY3650150) With/Without Topical Corticosteroid Treatment in Participants With Moderate-to-Severe Atopic Dermatitis
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: Placebo|DRUG: Lebrikizumab|DRUG: Topical Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Use Of Hydroxyurea in an African Region With Malaria
Status: COMPLETED
Conditions: Sickle Cell Anemia|Sickle Cell Disease|Malaria
Interventions: DRUG: Hydroxyurea|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adoptive Transfer of Tumor Infiltrating Lymphocytes for Metastatic Uveal Melanoma
Status: RECRUITING
Conditions: Uveal Neoplasms|Melanoma, Uveal
Interventions: BIOLOGICAL: Tumor Infiltrating Lymphocytes (TIL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MG1 Maraba/MAGE-A3, With and Without Adenovirus Vaccine With Transgenic MAGE-A3 Insertion in Incurable MAGE-A3-Expressing Solid Tumours
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced/Metastatic Solid Tumours
Interventions: BIOLOGICAL: MG1MA3|BIOLOGICAL: AdMA3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study That Compares the Extent to Which Apomorphine Becomes Available in the Body After Taking Either an Investigational Drug Containing Apomorphine or Apomorphine That is Injected Under the Skin in People With PD Complicated by "OFF" Episodes
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: APL-130277|DRUG: APO-go|DRUG: Apokyn
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Perioperative Pregabalin on the Incidence of Chronic Post-thoracotomy Pain Syndrome
Status: WITHDRAWN
Conditions: Chronic Pain
Interventions: DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Exercise and Training on Fat Oxidation During Overfeeding - the FeedEX Study
Status: TERMINATED
Conditions: Overfeeding and Exercise
Interventions: OTHER: overfeeding + exercise pre-training|BEHAVIORAL: fitness training|OTHER: overfeeding + exercise post-training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Nicotine-Qbeta Vaccine in Smokers
Status: COMPLETED
Conditions: Smokers
Interventions: BIOLOGICAL: CYT002-NicQb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First-in-Human Study of CAN04 in Patients With Solid Malignant Tumors
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer|Pancreatic Ductal Adenocarcinoma|Triple Negative Breast Cancer|Colorectal Cancer
Interventions: BIOLOGICAL: CAN04|DRUG: Cisplatin|DRUG: Gemcitabine|DRUG: Nab-paclitaxel|DRUG: Carboplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Tourniquet Use Have an Effect on Pain and Function After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Arthropathy of Knee|Pain, Joint
Interventions: PROCEDURE: Using Tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Energy Drinks on Electrocardiographic, Vascular and Hematologic Parameters in Healthy Volunteers
Status: TERMINATED
Conditions: Cardiovascular Diseases
Interventions: OTHER: energy drink|OTHER: Moxifloxacin 400mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Visual Outcomes of Tecnis Symfony Opti-Blue EDOF Intraocular Lens (IOL)
Status: NOT_YET_RECRUITING
Conditions: Cataract
Interventions: DEVICE: Tecnis Symfony OptiBlue/ Tecnis Symfony OptiBlue toric IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Two Tapering Strategies of Prednisone in Myasthenia Gravis
Status: COMPLETED
Conditions: Myasthenia Gravis
Interventions: DRUG: Prednisone - Azathioprine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Moderate-Intensity Exercise Versus High-Intensity Interval Training to Recover Walking Post-Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Moderate-Intensity Aerobic Training|BEHAVIORAL: High-Intensity Interval Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Custom-made Insoles on Foot Pressure Redistribution and Spatio - Temporal Gait Parameters in Sever Disease
Status: COMPLETED
Conditions: Calcaneal Apophysitis|Gait|Sever's Disease
Interventions: DEVICE: Study group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sulforadex in Healthy Human Males MAD
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Sulforadex|DRUG: alpha-cyclodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of MP-424/Peginterferon Alfa-2b/Ribavirin Combination in Treatment-Naïve Patients With Chronic Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: MP-424|DRUG: Ribavirin|DRUG: Peginterferon Alfa-2b|DRUG: Ribavirin|DRUG: Peginterferon Alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Two Techniques of Volemic Expansion in Hip Replacement Arthroplasty
Status: COMPLETED
Conditions: Hip Replacement Arthroplasty
Interventions: DRUG: Hydroxyethyl Starch|DRUG: Ringer's lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth, Allergy and Neurodevelopment in Infants on Hydrolysed Formula
Status: RECRUITING
Conditions: Infant Formula
Interventions: DIETARY_SUPPLEMENT: Partially hydrolysed formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating Innovative Technologies and Approaches to Addressing Cervical Cancer in Gaza and Maputo Cidade Provinces in Mozambique
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: BEHAVIORAL: HPV testing of women for cervical cancer screening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Postoperative Pain Control After Kidney Surgery : a Comparison of Intrathecal Morphine Plus PCA and PCA Only
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: spinal morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Saphenous Nerve and IPACK Blocks Versus Infiltration Analgesia After Anterior Cruciate Ligament Reconstruction
Status: COMPLETED
Conditions: Postoperative Pain|Anterior Cruciate Ligament Injury|Anterior Cruciate Ligament Rupture
Interventions: DRUG: Ropivacaine injection|DRUG: Ropivacaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sitafloxacin and Ertapenem Treatment for Acute Urinary Tract Infection Caused by E. Coli or K. Pneumoniae in Post-kidney Transplantation Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Anti-Infective Agents, Urinary|Escherichia Coli Infections|Klebsiella Infections|Kidney Transplantation|Urinary Tract Infections
Interventions: DRUG: Sitafloxacin|DRUG: Ertapenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluoride Release,Compressive Strength and Clinical Performance of a Bioactive Restorative Material in ART
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: Fuji IX EXTRA|DRUG: ACTIVA KIDS bioactive restorative material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Degarelix With or Without Apalutamide (ARN-509) Followed by Radical Prostatectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer|Neoadjuvant Therapy|Androgen Antagonists|Prostatectomy
Interventions: DRUG: ARN-509|DRUG: Degarelix|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Effectiveness Study of CNTO 1275 in Patients With Moderate to Severe Plaque-type Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Ustekinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Structural Imaging and Cognitive Functions in Adult Stem Cell Transplant Recipients Treated With Chemotherapy Alone or in Combination With Radiotherapy
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Acute Undifferentiated Leukemia|Biphenotypic Leukemia|Myelodysplastic Syndrome|Non-Hodgkin's Lymphoma
Interventions: PROCEDURE: MRI and cognitive evaluation|PROCEDURE: MRI and cognitive evaluation|PROCEDURE: brain MRI study and a brief neuropsychological evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing an Investigational Medication Versus an Approved Medication in Reducing Cholesterol Levels (0653-025)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: MK0653, ezetimibe / Duration of Treatment: 28 weeks|DRUG: Comparator: atorvastatin / Duration of Treatment: 28 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Advancing Child Competencies by Extending Supported Services (ACCESS) for Families Program
Status: COMPLETED
Conditions: Developmental Delay|Disruptive Behavior
Interventions: BEHAVIORAL: Internet-delivered Parent-Child Interaction Therapy (I-PCIT)|OTHER: Referrals as Usual (RAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Increasing Donor Designation Rates in Teenagers: Effectiveness of a Driver's Education Intervention
Status: COMPLETED
Conditions: Organ Donor Registration|Organ Donation Education
Interventions: BEHAVIORAL: Organ Donation Education: Testimonial Messaging|BEHAVIORAL: Organ Donation Education: Informational Messaging|BEHAVIORAL: Organ Donation Education: Blended Messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of NMS-03305293 in Pts With Selected Advanced/Metastatic Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced/Metastatic Solid Tumors
Interventions: DRUG: NMS-03305293
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Lumen Opening With Self-Forming Magnetic Anastomosis
Status: NOT_YET_RECRUITING
Conditions: Small Bowel Anastomosis
Interventions: DEVICE: Small Bowel Anastomosis with Flexagon SFM Device with OTOLoc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Bone Marrow Mononuclear Cells Therapy in Diabetic Lower Limb Ischemia
Status: UNKNOWN
Conditions: Diabetes|Lower Limb Ischemia
Interventions: BIOLOGICAL: autologous bone marrow mononuclear cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Definition Transcranial Direct Current Stimulation as a Treatment of Negative Symptoms of Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DEVICE: HD-tDCS|DEVICE: Sham HD-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sub-Sensitivity to Long-Acting Bronchodilators (LABA)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: fluticasone propionate and salmeterol|DRUG: budesonide and formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ixabepilone as Second-line Therapy for Locally Advanced, Recurrent, or Metastatic Endometrial Cancer
Status: TERMINATED
Conditions: Endometrial Cancer
Interventions: DRUG: Ixabepilone|DRUG: Doxorubicin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ENDURE - Efficacy and Safety of AOP2014 With CML Patients in Remission
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia in Remission
Interventions: DRUG: AOP2014 / Pegylated-Proline-interferon alpha-2b|OTHER: Surveillance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Sham-Controlled Study to Evaluate the Safety and Efficacy of a Smart, Self-Adjusting, Surgery-Free, Wearable Bladder Neuromodulation System for Overactive Bladder
Status: TERMINATED
Conditions: Overactive Bladder|Urinary Urge Incontinence|Urge Incontinence
Interventions: DEVICE: Avation System|DEVICE: Sham Avation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modified Method of Eversion Carotid Endarterectomy in Patients With Extensive Atherosclerotic Disease of Carotid Bifurcation
Status: COMPLETED
Conditions: Carotid Stenosis|Carotid Artery Diseases
Interventions: PROCEDURE: Modified method of eversion carotid endarterectomy|PROCEDURE: Standard method of eversion carotid endarterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Galactooligosaccharide Enhance Nutrient Availability
Status: RECRUITING
Conditions: Exogenous Carbohydrate Oxidation
Interventions: DIETARY_SUPPLEMENT: Bimuno Daily|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Child Abuse and Neglect Prevention Program on Awareness Levels and Child Abuse Potential of Pregnant Women
Status: COMPLETED
Conditions: Child Abuse
Interventions: BEHAVIORAL: Child Abuse and Neglect Prevention Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Extralevator Versus Standard Abdominoperineal Resection For Rectal Adenocarcinoma
Status: UNKNOWN
Conditions: Rectal Adenocarcinoma
Interventions: PROCEDURE: extralevator APR|PROCEDURE: APR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vigabatrin With High Dose Prednisolone Combination Therapy vs Vigabatrin Alone for Infantile Spasm
Status: RECRUITING
Conditions: Infantile Spasm|West Syndrome
Interventions: DRUG: Combination therapy with vigabatrin and prednisolone|DRUG: Vigabatrin Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Electroencephalography (EEG) and Transcranial Current Stimulation (tCS) to Study and Modulate Cognition Study
Status: COMPLETED
Conditions: Inter-individual Variability
Interventions: DEVICE: Transcranial Random Noise Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of a Brown Seaweed Powder for Glycemic Control
Status: COMPLETED
Conditions: Blood Glucose
Interventions: DIETARY_SUPPLEMENT: 500 mg InSea2®|DIETARY_SUPPLEMENT: 250 mg InSea2®|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Dimensional Changes at Different Implant-to-abutment Connections: a 1-year Clinical and Radiological Study
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially
Interventions: PROCEDURE: implant insertion and abutment connection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Trypsin-Chymotrypsin and Naproxen Sodium for Post-endodontic Treatment Pain: A Randomized Controlled Trial
Status: RECRUITING
Conditions: Effect of Drug
Interventions: DRUG: Trypsin-Chymotrypsin|DRUG: Naproxen Sodium 550mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relaxation Exercise With Virtual Reality Glasses and Episiotomy-induces Perineal Pain and Fear
Status: COMPLETED
Conditions: Episiotomy Wound
Interventions: DEVICE: Virtual reality glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bilateral Simultaneous Total Knee Arthroplasty for Bilateral Gonarthrosis
Status: COMPLETED
Conditions: Bilateral Total Knee Arthroplasty|Gonarthrosis; Primary, Bilateral
Interventions: PROCEDURE: Two-team simultaneous bilateral total knee arthroplasty|PROCEDURE: Single-team simultaneous bilateral total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Ability of TNFR:Fc to Decrease the Amount of IL-6 (Interleukin-6) and TNF-alpha (Tumor Necrosis Factor) in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Tumor Necrosis Factor soluble receptor-immunoadhesin complex
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Treatment Off Gingival Recession Defects Using a Xenogenic Acellular Dermal Matrix Compared to Connective Tissue Graft.
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: transplants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aliskiren Plus HCTZ Compared to Aliskiren in Metabolic Syndrome Patients With Stage 2 Systolic Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Aliskiren|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Olanzapine for Nausea After Surgery
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Olanzapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Primary Study to Demonstrate Non-inferiority and Immunogenicity of GSK Biologicals' Meningococcal Vaccine 134612
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Nimenrix (Meningococcal vaccine 134612)|BIOLOGICAL: Twinrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Preliminary Investigation of ViaShield™ Amnion Patch as an Anti-Adhesive Barrier in Hemicraniectomies
Status: WITHDRAWN
Conditions: Hemicraniectomies
Interventions: BIOLOGICAL: ViaShield
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MET-2 Clinical Study for Recurrent Clostridium Difficile Infection (CDI)
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: DRUG: MET-2|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irinotecan Liposome Combined With Oxaliplatin and Tegafur as Adjuvant Therapy for Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer|Adjuvant Therapy
Interventions: DRUG: Irinotecan liposome injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HM15136 Treatment for 8 Weeks in Subjects Aged ≥2 Years With Congenital Hyperinsulinism (CHI)
Status: RECRUITING
Conditions: Congenital Hyperinsulinism
Interventions: DRUG: HM15136
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Palifermin in Subjects Receiving Radiation Therapy and Chemotherapy Followed by Blood Stem Cell Support
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Myeloma
Interventions: DRUG: Palifermin 6 x 60 μg/kg/day|DRUG: Palifermin 2 x 180 μg/kg/day|RADIATION: radiotherapy|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spectral Characteristics of Memory Transformation
Status: RECRUITING
Conditions: Healthy
Interventions: OTHER: Transcranial alternating current stimulation (tACS) combined with behavioral intervention|OTHER: Inactive (sham) stimulation combined with behavioral intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of add-on Montelukast to Inhaled Budesonide in the Treatment of Nonasthmatic Eosinophilic Bronchitis
Status: UNKNOWN
Conditions: Nonasthmatic Eosinophilic Bronchitis
Interventions: DRUG: Montelukast|OTHER: placebo to montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Docetaxel, Cisplatin, and Fluorouracil (Modified DCF) With Bevacizumab in Patients With Unresectable or Metastatic Gastroesophageal Adenocarcinoma
Status: COMPLETED
Conditions: Stomach Neoplasms|Esophageal Neoplasms
Interventions: DRUG: Docetaxel, Cisplatin, Fluorouracil, Bevacizumab, Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study of TAK-828 Escalating Multiple-Doses in Healthy Participants
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-828|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase 1b Study Evaluating the Safety and Tolerability of ABT-199 in Combination With Rituximab in Subjects With Relapsed Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma
Status: COMPLETED
Conditions: Small Lymphocytic Lymphoma|Chronic Lymphocytic Leukemia
Interventions: DRUG: ABT-199|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-incision Laparoscopic (SILS) Versus Conventional Laparoscopic Appendectomy for the Treatment of Acute Appendicitis
Status: TERMINATED
Conditions: Appendicitis
Interventions: PROCEDURE: SILS appendectomy|PROCEDURE: conventional laparoscopic appendectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Enhanced External Counterpulsation on Ventricular Function
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DEVICE: Experimental: Enhanced External Counterpulsation|DRUG: Standard medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Graduated Recovery Intervention Program for Enhancing Treatment for First-Episode Psychosis
Status: COMPLETED
Conditions: Psychotic Disorders|Schizophrenia
Interventions: BEHAVIORAL: Graduated Recovery Intervention Program (GRIP)|BEHAVIORAL: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Shared Decision Making Training for Inpatients With Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: patient training in shared decision making|BEHAVIORAL: cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Selection of Farnesoid X Receptor (FXR) Ligands on the Reactivation of Latent HIV Proviruses
Status: TERMINATED
Conditions: Human Immunodeficiency Virus I Infection
Interventions: PROCEDURE: Blood collection.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Outcomes Between Tibial Preservation Bone Cut and Conventional Tibial Bone Cut Following Medial UKA
Status: UNKNOWN
Conditions: Knee Osteoarthritis|Knee Arthropathy
Interventions: PROCEDURE: tibial preservation bone cut
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid to Reduce Delirium After Gastrointestinal Surgery: the TRIGS-D Trial
Status: RECRUITING
Conditions: Surgical Site Infection|Dementia|Cognition
Interventions: DRUG: Tranexamic Acid 100Mg/ml Inj Vial 10ml|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Dose Escalation/Expansion Study of LDK378 in Patients With Tumors Characterized by Genetic Abnormalities in Anaplastic Lymphoma Kinase
Status: COMPLETED
Conditions: Tumors Characterized by Genetic Abnormalities of ALK
Interventions: DRUG: LDK378
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT