pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of RR and MT on Patient With Stroke
Status: UNKNOWN
Conditions: Cerebrovascular Accident
Interventions: BEHAVIORAL: Mirror Therapy|BEHAVIORAL: Conventional Rehabilitation|BEHAVIORAL: Robotic Rehabilitation|BEHAVIORAL: Robotic rehabilitation with FES|BEHAVIORAL: Robotic Rehabilitation with PI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Irinotecan Administered as a Continuous Infusion and Radiation Therapy for Upper Gastrointestinal Cancers
Status: COMPLETED
Conditions: Pancreatic Cancer|Gastric Cancer|Duodenum Cancer|Bile Duct Cancer
Interventions: DRUG: irinotecan|PROCEDURE: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Transplantation of EPCs to Treat Idiopathic Pulmonary Arterial Hypertension
Status: UNKNOWN
Conditions: Idiopathic Pulmonary Arterial Hypertension
Interventions: PROCEDURE: Transplantation of autologous endothelial progenitor cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Kefir and Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome|Obesity|Hypertension|Hyperlipidemias|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Kefir|DIETARY_SUPPLEMENT: Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Gather Information How Well Three Different Doses of BAY1817080 Given Twice Daily Over 12 Weeks Work in Comparison to an Inactive Pill (Placebo) and Elagolix in Women Suffering From Pain Related to a Condition Where the Tissue That Usually Grows Inside the Womb Grows Outside of the Womb
Status: TERMINATED
Conditions: Endometriosis
Interventions: DRUG: BAY1817080|DRUG: Elagolix|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Albuterol Sulfate For Acute Wheezing Due To Obstructive Airways Disease In Children
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: albuterol sulfate inhalation aerosol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Tolerability of BMN 111 Administered to Healthy Adult Volunteers
Status: COMPLETED
Conditions: Achondroplasia
Interventions: DRUG: BMN 111|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Arterial Spin Labeling Blood Flow Magnetic Resonance Imaging for the Evaluation of Response to Therapy in Metastatic Renal Cell Carcinoma
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: PROCEDURE: Arterial Spin Labeling Blood Flow Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single Ascending Dose PK, Oral Bioavailability and Food Effect Study in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Indoximod HCL (F2) tablets|DRUG: Indoximod base formulation|OTHER: Placebo|DRUG: Indoximod HCL (F2) tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Graded Weight-bearing Exercise in Patients With Knee Osteoarthritis.
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: anti-gravity treadmill|OTHER: Weight-bearing exercises for knee flexors and extensors|OTHER: Non weight-bearing exercises for knee flexors and extensors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gut Oxalate Absorption in Calcium Oxalate Stone Disease
Status: RECRUITING
Conditions: Kidney Stone|Kidney Calculi|Urolithiasis|Urolithiasis, Calcium Oxalate|Nephrolithiasis|Nephrolithiasis, Calcium Oxalate|Oxalate Urolithiasis|Oxaluria|Healthy
Interventions: DIETARY_SUPPLEMENT: Low-oxalate diet|DIETARY_SUPPLEMENT: High-oxalate diet|OTHER: soluble oxalate gut absorption test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Investigate Behavioral and Other Co-Occurring Outcomes With Epidiolex as Add-On Therapy in Participants Aged 1 to 65 Years of Age With Tuberous Sclerosis Complex
Status: RECRUITING
Conditions: Tuberous Sclerosis Complex Associated Neuropsychiatric Disease
Interventions: DRUG: Cannabidiol Oral Solution [Epidiolex]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Incision Laparoscopic Surgery in Treating Patients With Colorectal Disease
Status: COMPLETED
Conditions: Adenomatous Polyp|Crohn Disease|Familial Adenomatous Polyposis|Hereditary Intestinal Polyposis Syndrome|Recurrent Colon Cancer|Stage I Colon Cancer|Stage IIA Colon Cancer|Stage IIB Colon Cancer|Stage IIC Colon Cancer|Stage IIIA Colon Cancer|Stage IIIB Colon Cancer|Stage IIIC Colon Cancer
Interventions: PROCEDURE: therapeutic laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Dynamic Haptic Robotic Trainer (DHRT) and DHRT+ for CVC Insertion Training for Surgical Residents
Status: RECRUITING
Conditions: Central Line Complication|Central Line Infection
Interventions: OTHER: Dynamic Haptic Robotic Trainer (DHRT)|OTHER: Advanced Dynamic Haptic Robotic Trainer (DHRT+)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Prevention Education in Caries Formation in Pediatric Patients With Leukemia
Status: TERMINATED
Conditions: Leukemia
Interventions: PROCEDURE: Dental Procedure|OTHER: Educational Intervention (prevention education)|OTHER: Interview|OTHER: Survey Administration|OTHER: Educational Intervention (one-on one education)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Filter Ventilation on Sensory Response, Smoking Topography, and Inhalation in Current Every Day Cigarette Smokers
Status: COMPLETED
Conditions: Cigarette Smoker|Current Every Day Smoker
Interventions: DEVICE: Medical Device|OTHER: Questionnaire Administration|BEHAVIORAL: Tobacco Smoking
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prediction of Neoadjuvant Chemotherapy Efficacy in Locally Advanced Gastric Cancer
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DIAGNOSTIC_TEST: 68Ga-FAPI-04 PET/CT and 18F-FDG PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Peer-led Social Media Intervention to Prevent HIV Among Young Men Who Have Sex With Men (YMSM)
Status: COMPLETED
Conditions: Pre-Exposure Prophylaxis|Hiv|Men
Interventions: BEHAVIORAL: PrEP messages|BEHAVIORAL: Heath messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders
Status: RECRUITING
Conditions: AMPD3, OMIM*102772, AMP Deaminase Deficiency|AK1, OMIM *103000, Adenylate Kinase Deficiency|AMPD1, OMIM *102770, Myopathy Due to Myoadenylate Deaminase Deficiency|TPMT, OMIM *187680, Thoipurines, Poor Metabolism of|IMPDH1, OMIM *146690, Retinitis Pigmentosa Type 10, Leber Congenital Amauriosis Type 11|APRT, OMIM *102600, Adenine Phosphoribosyltransferase Deficiency|HPRT1, OMIM *308000 Lesch-Nyhan Disease|XDH, OMIM *607633, Xanthinuria Type 1|SLC2A9, OMIM *606142 Hypouricemia|SLC22A12, OMIM *607096 Hypouricemia|PRPS1 Def, OMIM *311850, Arts Syndrome; Charcot-Marie-Tooth Disease|PRPS1 SA, OMIM *311850 Gout, PRPS-related Phosphoribosylpyrophosphate Synthetase Superactivity|AMPD2, OMIM *102771, Spastic Paraplegia 63; Pontocerebellar Hypoplasia|ITPA, OMIM *147520, Inosine Triphosphatase Deficiency; Developmental and Epileptic Encephalopathy 35|ADSL, OMIM *608222, Adenylosuccinate Lyase Deficiency|PNP, OMIM *164050, Nucleoside Phosphorylase Deficiency|ADA2, OMIM *607575,Sneddon Syndrome; VAIHS|CAD, *1140120, Developmental and Epileptic Encephalopathy|UPB1, OMIM *606673, Beta-ureidopropionase Deficiency|DPYS, OMIM *613326, Dihydropyrimidinase Deficiency|DPYD, OMIM *274270, Dihydropyrimidine Dehydrogenase Deficiency|DHODH, OMIM *126064, Miller Syndrome (Postaxial Acrofacial Dysostosis)|UMPS, OMIM *613891, Orotic Aciduria|NT5C3A<TAB>, OMIM *606224, Anemia, Hemolytic, Due to UMPH1 Deficiency|UNG, OMIM *191525, Hyper-IgM Syndrome 5|AICDA, OMIM *605257, Immunodeficiency With Hyper-IgM, Type 2; HIGM2|Purine-Pyrimidine Metabolism|Metabolic Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TWK10 Improves Muscle Mass and Functional Performance in Frail Older Adults
Status: COMPLETED
Conditions: Frail Elderly Syndrome|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Lactobacillus plantarum TWK10-L|DIETARY_SUPPLEMENT: Maltodextrin|DIETARY_SUPPLEMENT: Lactobacillus plantarum TWK10-H
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Istradefylline (KW-6002) for the Treatment of Restless Legs Syndrome
Status: COMPLETED
Conditions: Sleep Disorder|Restless Legs Syndrome
Interventions: DRUG: Istradefylline (KW-6002)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Micron Tracker: Computer-Assisted Orthognathic Surgery With a Third Generation Optic Repositioning System
Status: SUSPENDED
Conditions: Computer-Assisted Surgery|Maxillofacial Surgery
Interventions: DEVICE: MicronTracker
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Complex Treatment of a Chronic Anal Fissure
Status: RECRUITING
Conditions: Fissure in Ano
Interventions: DRUG: IncobotulinumtoxinA 50 U Intramuscular Powder for Solution|PROCEDURE: Lateral subcutaneous sphincterotomy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety, Tolerability, PK, and PD of ILV-094 Administered IV or SC to Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ILV-094
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Intra-tumoural Diffusing Alpha Radiation Emitters for the Treatment of Vulva Cancer
Status: RECRUITING
Conditions: Vulva Cancer, Recurrent|Vulvar Squamous Cell Carcinoma|Vulva Cancer
Interventions: RADIATION: DaRT Diffusing Alpha-emitters Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Evaluation of Bilayered Cellular Matrix (OrCel) for the Treatment of Venous Ulcers
Status: COMPLETED
Conditions: Venous Leg Ulcer|Venous Stasis Ulcer
Interventions: DEVICE: Bilayered Cellular Matrix (OrCel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide Drug Interaction Study In Cancer Patients
Status: TERMINATED
Conditions: Nausea and Vomiting, Chemotherapy-Induced
Interventions: DRUG: Oral GW679769|DRUG: IV Cyclophosphamide 500-700mg/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 38 Week Extension Study to CAIN457C2303
Status: TERMINATED
Conditions: Uveitis
Interventions: DRUG: AIN457|DRUG: AIN457|DRUG: Placebo AIN457
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RAD001 in Combination With Cetuximab and Cisplatin in Recurrent and Metastatic SCCHN
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DRUG: RAD001|DRUG: Cetuximab|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Essential Oil for Chronic Low Back Pain
Status: UNKNOWN
Conditions: Chronic Low-back Pain
Interventions: OTHER: usual care and topical essential copaiba oil|OTHER: usual care and placebo treatment|OTHER: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Zoledronic Acid on Chemotherapy Induced Bone Loss
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Lymphoma
Interventions: DRUG: Zoledronic Acid|DRUG: Vitamin D|DRUG: Calcium Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Posaconazole (Noxafil®) as Prophylaxis for Invasive Fungal Infections
Status: COMPLETED
Conditions: Allogeneic Stem Cell Transplant|Acute Graft Versus Host Disease|Acute Myeloid Leucaemia|Myelo Dysplastic Syndrome
Interventions: DRUG: posaconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability of Inhaled Treprostinil in Adult PH Due to COPD
Status: WITHDRAWN
Conditions: Pulmonary Hypertension|Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Inhaled Treprostinil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk-adapted, MRD-directed Therapy for Young Adults With Newly Diagnosed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: OTHER: Risk-adapted, MRD-directed therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study to Evaluate the Effects of Ezogabine/Retigabine Added to Existing Anti-epileptic Drug(s) on Urinary Voiding Function in Subjects With Partial Onset Seizures
Status: TERMINATED
Conditions: Epilepsy
Interventions: DRUG: ezogabine/retigabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy in Treating Patients With Recurrent or Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: trimetrexate glucuronate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: "A Pilot Study to Determine the Safety of Campath-1H (Anti-CD52) Therapy in Primary Renal Allograft Transplantation"
Status: COMPLETED
Conditions: Renal Transplant
Interventions: DRUG: Campath-1H
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Study Comparing MB05 (Proposed Palivizumab Biosimilar), EU-sourced Synagis® and US-sourced Synagis® in Healthy Volunteers.
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: MB05 (Proposed palivizumab biosimilar)|DRUG: EU-Synagis®|DRUG: US-Synagis®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Uninterrupted Direct-acting Oral Anticoagulation in Patients Undergoing Transradial Percutaneous Coronary Procedures
Status: RECRUITING
Conditions: Coronary Artery Disease|Bleeding|Direct Acting Anticoagulant Adverse Reaction
Interventions: DRUG: Direct-acting oral anticoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hyperbaric Oxygen Therapy in Calcaneal Intraarticular Fractures: Can it Decrease the Soft-tissue Complication Rate?
Status: COMPLETED
Conditions: Microcirculation|Wound Healing
Interventions: PROCEDURE: HBOT|PROCEDURE: Placebo (Sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy-free Regimen of Venetoclax, Azacitidine Plus Orebatinib (VAO Regimen) for Newly Diagnosed ph+ALL
Status: RECRUITING
Conditions: Ph-Positive Acute Lymphoblastic Leukemia
Interventions: DRUG: Venetoclax|DRUG: Azacitidine|DRUG: Orebatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Berinert (C1INH) vs Placebo for DGF/IRI
Status: ACTIVE_NOT_RECRUITING
Conditions: End Stage Renal Disease|Chronic Kidney Diseases
Interventions: DRUG: Berinert|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Electrical Stimulation of the Sphenopalatine Ganglion for the Treatment of Migraine Headaches
Status: COMPLETED
Conditions: Migraine Headache
Interventions: DEVICE: Deep Brain Stimulation of SPG for Migraine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of ARQ-154 Foam in Subjects With Seborrheic Dermatitis
Status: COMPLETED
Conditions: Seborrheic Dermatitis
Interventions: DRUG: Roflumilast Foam 0.3%|DRUG: Vehicle foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Luminal Expansion Following Stenting of Femoro-popliteal Occlusive Disease
Status: WITHDRAWN
Conditions: Femoropopliteal Stenosis
Interventions: DEVICE: Supera Stent|DEVICE: Life Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Leflunomide in Previously Treated Metastatic Triple Negative Cancers
Status: RECRUITING
Conditions: Breast Neoplasms|Breast Diseases|Metastatic Triple Negative Breast Cancer
Interventions: DRUG: Leflunomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cediranib Maleate in Treating Patients With Malignant Mesothelioma That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Advanced Malignant Mesothelioma|Epithelial Mesothelioma|Localized Malignant Mesothelioma|Recurrent Malignant Mesothelioma|Sarcomatous Mesothelioma
Interventions: DRUG: cediranib maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alpha-TEA and Trastuzumab for the Treatment of Refractory HER2+ Metastatic Breast Cancer
Status: SUSPENDED
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|HER2 Positive Breast Carcinoma|Metastatic Breast Carcinoma|Refractory Breast Carcinoma
Interventions: DRUG: Alpha-tocopheryloxyacetic Acid|BIOLOGICAL: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pipelle® Under Ultrasound Guidance (PUG) to Investigate Post-menopausal Bleeding.
Status: RECRUITING
Conditions: Endometrial Cancer|Post-Menopausal Bleeding|Endometrial Hyperplasia
Interventions: PROCEDURE: Pipelle® endometrial biopsy performed under transabdominal ultrasound guidance|PROCEDURE: Pipelle® endometrial biopsy performed without ultrasound guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate and Compare Injections of Autologous Mixed Population of Dermal Cells Cells Into the Balding Scalp of Subjects With Hair Loss (CA-0006931)
Status: COMPLETED
Conditions: Androgenetic Alopecia|Male Pattern Baldness|Female Pattern Baldness
Interventions: BIOLOGICAL: Autologous cultured mixed population of dermal cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Human Umbilical Cord-derived Mesenchymal Stem Cells for Decompensated Cirrhosis (MSC-DLC-1)
Status: RECRUITING
Conditions: Decompensated Cirrhosis
Interventions: BIOLOGICAL: Human Umbilical Cord-derived Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SCLC on the 2nd Line With Relapsed After Response to Chemotherapy GFPC 01-2013
Status: UNKNOWN
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Carboplatin|DRUG: Etoposide|DRUG: Topotecan|DEVICE: CT scans
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Response Study of Inhaled Ciclesonide (Glucocorticosteroid) to Patients With Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: AVE2635A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Modulation of the Gut Microbiota of Professional Athletes With Sauerkraut Supplementation
Status: COMPLETED
Conditions: Gastrointestinal Microbiome
Interventions: OTHER: Sauerkraut (Brassica oleracea v. capitata)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparisons Of Different Antiplaque Agents On Gingivitis In Orthodontic Patients
Status: COMPLETED
Conditions: Gingivitis
Interventions: DRUG: Chlorhexidine Gluconate|DRUG: Metronidazole|DRUG: combination gel (chlorhexidine and metronidazole)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Personalized Vaccine With SOC Chemo Followed by Nivo in Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Adenocarcinoma
Interventions: BIOLOGICAL: Autologous Dendritic Cell Vaccine Loaded with Personalized Peptides (PEP-DC vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LIFEGUARD Study - Continuous Respiratory Monitoring on the General Ward
Status: TERMINATED
Conditions: Respiratory Complication
Interventions: BEHAVIORAL: Capnostream 20 monitoring|DEVICE: PM1000N-RR monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: A 28-Day Polysomnographic Study of Gabapentin in Transient Insomnia Induced by a Sleep Phase Advance
Status: COMPLETED
Conditions: Transient Insomnia
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kangaroo Mother Care to Prevent Hypothermia in Preterm Infants
Status: COMPLETED
Conditions: Hypothermia, Newborn
Interventions: OTHER: Continuous Kangaroo Mother Care to 1 hour after birth|OTHER: Standard Kangaroo Mother Care to 1 hour after birth|OTHER: Continuous Kangaroo Mother Care to discharge|OTHER: Standard Kangaroo Mother Care to discharge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Glucocorticoid Injection in Patients With Lumbar Radicular Pain
Status: COMPLETED
Conditions: Radiculopathy Lumbar
Interventions: DRUG: Glucocorticoids|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effects of Diaphragm Exercises in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy Spastic Diplegia
Interventions: OTHER: Diaphragmatic exercises|OTHER: conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outpatient Platelet Transfusions in Myelodysplastic Syndromes and Leukemia: The OPTIMAL Pilot
Status: TERMINATED
Conditions: Myelodysplastic Syndrome|Leukemia
Interventions: OTHER: Platelet Transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Dyspepsia - Effect of Acid-Reducing Treatment and Information.
Status: TERMINATED
Conditions: Dyspepsia
Interventions: PROCEDURE: Individualized and comprehensive information|DRUG: Lanzo Melt|DRUG: Lanzo Melt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of SlimTrack® Platform on Diet Adherence, Anthropometry and Arterial Stiffness in Postmenopausal Women
Status: RECRUITING
Conditions: Menopause|Obesity|Overweight
Interventions: BEHAVIORAL: SlimTrack Plataform|BEHAVIORAL: Diet prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Role of PRoactivE Coaching on PAtient REported Outcome in Advanced or Metastatic RCC Treated With Sunitinib or a Combination of Pembrolizumab + Axitinib or Avelumab + Axitinib in First Line Therapy
Status: RECRUITING
Conditions: Renal Cell Carcinoma, Metastatic|Renal Cell Cancer, Recurrent
Interventions: BEHAVIORAL: Concomitant coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Y90-Radioembolization With Nivolumab in Asians With Hepatocellular Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: HepatoCellular Carcinoma
Interventions: RADIATION: Y-90 Radioembolization|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravascular ECG During Insertion of Peripheral Inserted Central-venous Catheters: Replacement for Chest X-ray?
Status: COMPLETED
Conditions: Catheterization, Peripheral|Electrocardiography
Interventions: DEVICE: IVECG|DEVICE: Chest X-ray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Guided Self-Help for Parents of Children With Attention-Deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention-Deficit/Hyperactivity Disorder
Interventions: BEHAVIORAL: CBT Based Self-help Workbook + Counseling Telephone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of the Co-administration of VLX-1005 and Argatroban in Healthy Human Subjects
Status: COMPLETED
Conditions: Heparin-induced Thrombocytopenia
Interventions: DRUG: VLX-1005|DRUG: Argatroban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Ratio of Femoral Vein Diameter to Femoral Artery Diameter to Predict Fluid Responsiveness in Children
Status: RECRUITING
Conditions: Pediatric ALL|Fluid Overload
Interventions: DIAGNOSTIC_TEST: Ratio of Femoral Vein Diameter to Femoral Artery Diameter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Long Limb Roux-en Y Reconstruction
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2 in Nonobese|Gastric Cancer
Interventions: PROCEDURE: Long limb Roux-en Y reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remifentanil Tapering and Post-adenotonsillectomy Pain in Children
Status: TERMINATED
Conditions: Child, Only|Pain|Tonsillectomy|Remifentanil
Interventions: DRUG: Remifentanil|DRUG: Sodium Chloride 9mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ferric Citrate and Chronic Kidney Disease in Children
Status: RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: DRUG: Ferric Citrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Virtual Reality on Upper Limbs at Different Ages of Subjects With Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Leap Motion Controller on flat display
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pralatrexate to Treat Participants With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma, B-Cell
Interventions: DRUG: Pralatrexate|DIETARY_SUPPLEMENT: Vitamin B12|DIETARY_SUPPLEMENT: Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utility of Dynamic Variables Measured by Calibrated Pulse Contour Analysis of Oesophageal Doppler Monitor for Predicting Fluid Responsiveness During Robot-Assisted Laparoscopic Prostatectomy
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: PROCEDURE: pneumoperitoneum|DEVICE: oesophageal Doppler monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Phase II Study of an Anti-Tumor Immunotherapy Regimen Comprised of Pegylated Interferon-Alpha 2b and HyperAcute Melanoma Vaccine for Subjects With Advanced Melanoma
Status: UNKNOWN
Conditions: Melanoma
Interventions: BIOLOGICAL: HyperAcute vaccine|DRUG: Pegylated Interferon-Alpha 2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Yield Intraoperative, Autologous Platelet Apheresis
Status: COMPLETED
Conditions: Allogenic Transfusion of Platelets During Cardiac Surgery
Interventions: PROCEDURE: Aphersis Treatment Arm|OTHER: Control Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate vs. Delayed Insertion of Copper T 380A IUD After Termination of Pregnancy Over 12-weeks Gestation
Status: COMPLETED
Conditions: Contraception Behavior
Interventions: DEVICE: Copper T 380A IUD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of OT-101 With mFOLFIRINOX in Patients With Advanced and Unresectable or Metastatic Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: OT-101|DRUG: mFOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Whey Protein Pre-meals on Post-prandial Glucose
Status: COMPLETED
Conditions: Prediabetic State
Interventions: DIETARY_SUPPLEMENT: Whey protein isolate|DIETARY_SUPPLEMENT: Whey protein microgel|DIETARY_SUPPLEMENT: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Hemay005 in Adult With Atopic Dermatitis
Status: COMPLETED
Conditions: Hemay005, Atopic Dermatitis
Interventions: DRUG: Hemay005
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-PBR06/Total Body PET Imaging in Patients With STEMI
Status: RECRUITING
Conditions: Myocardial Infarction
Interventions: PROCEDURE: percutaneous coronary intervention (PCI)|DEVICE: total body PET/CT scan|PROCEDURE: Coronary Angiography (CAG)|DRUG: TSPO injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Video-conferencing FACT for Young Children With Special Needs
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Attention Deficit Hyperactivity Disorder|Specific Learning Disorder|Communication Disorders|Motor Disorders
Interventions: BEHAVIORAL: Focused Acceptance and Commitment Therapy|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Effect of One-session MRT in Hemiparetics
Status: COMPLETED
Conditions: Hemiparesis;Poststroke/CVA|Satisfaction, Patient
Interventions: OTHER: Matrix-Rhythm Therapy|OTHER: Conventional physiotherapy and rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of RCT-01 in Men and Women With Unilateral, Chronic Achilles Tendinosis
Status: TERMINATED
Conditions: Tendinosis|Tendinopathy
Interventions: DRUG: RCT-01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Dexketoprofen, Paracetamol and Ibuprofen in the Treatment of Primary Dysmenorrhea
Status: UNKNOWN
Conditions: Dysmenorrhea
Interventions: DRUG: paracetamol|DRUG: Dexketoprofen Trometamol|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigate Impact of Yasmin vs Microgynon on Hemostasis Parameters in Healthy Women
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Yasmin (DRSP 3mg/EE 0.03 mg)|DRUG: Microgynon (LNG 0.15 mg/EE 0.03 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain and Bleeding in Subjects With Acute Anal Fissure: Comparative Evaluation of Three Treatments
Status: COMPLETED
Conditions: Acute Anal Fissure
Interventions: DRUG: Centella|DRUG: Proctocella|DRUG: Flavonil® cps|DRUG: Flavonil® Cream|DRUG: Rectalgan Mousse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of AG-013736 (Axitinib) As Second-Line Treatment In Patients With Metastatic Renal Cell Cancer (mRCC)
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: AG-013736
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Impact of Intermittent Preventive Treatment in Schools on Malaria, Anaemia and Education.
Status: COMPLETED
Conditions: Malaria, Falciparum
Interventions: DRUG: Intermittent preventive treatment (SP and amodiaquine)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Platelet-rich Fibrin Matrix on Skin Rejuvenation
Status: COMPLETED
Conditions: Skin Rejuvenation|Skin Quality|Wrinkle|Nasolabial Fold
Interventions: PROCEDURE: PRFM injection|PROCEDURE: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Comparative Analysis Between Motilitone and Gasmotin for the Symptom Relief in Gallstone Patients With Functional Dyspepsia
Status: UNKNOWN
Conditions: Gallstone
Interventions: DRUG: Motilitone|DRUG: Gasmotin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Erector Spinae Plane Block: A Comparative Study to Assess Its Analgesic Efficacy in Pediatric Patients Undergoing Aortic Coarctation Repair
Status: UNKNOWN
Conditions: Anesthesia
Interventions: PROCEDURE: Nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The PRIMO Study: Paricalcitol Capsules Benefits Renal Failure Induced Cardiac Morbidity in Subjects With Chronic Kidney Disease Stage 3/4
Status: COMPLETED
Conditions: Chronic Kidney Disease|Left Ventricular Hypertrophy
Interventions: DRUG: paricalcitol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Visionary Study: Phase 3 Trial of Sibeprenlimab in Immunoglobulin A Nephropathy (IgAN)
Status: ACTIVE_NOT_RECRUITING
Conditions: Immunoglobulin A Nephropathy
Interventions: DRUG: Sibeprenlimab 400 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Scarring in Stratagraft-treated vs. Autograft-treated Burn Wounds: a Clinical and Histological Investigation
Status: ACTIVE_NOT_RECRUITING
Conditions: Burn Scar|Scar
Interventions: OTHER: Punch biopsy|OTHER: non-invasive photography, assessments, and measurements
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service
Status: RECRUITING
Conditions: Anesthesia
Interventions: DEVICE: Continuous Adductor Canal Catheter (ACC)|DEVICE: Adductor Canal block with sham catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Followed By Autologous Stem Cell Transplant, and White Blood Cell Infusions in Treating Patients With Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: therapeutic autologous lymphocytes|DRUG: carmustine|DRUG: cytarabine|DRUG: etoposide|DRUG: melphalan|PROCEDURE: peripheral blood stem cell transplantation (PBSCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eplerenone for Subclinical Cardiomyopathy in Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: eplerenone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Quadrivalent Influenza Vaccine Among Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Investigational Quadrivalent Inactivated Influenza Vaccine, No Preservative|BIOLOGICAL: Investigational Trivalent Inactivated Influenza Vaccine, No Preservative|BIOLOGICAL: Fluzone®: 2010-2011 Trivalent Inactivated Influenza Vaccine, No Preservative|BIOLOGICAL: Fluzone®: 2010-2011 Trivalent Inactivated Influenza Vaccine, No Preservative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy Of PF-05089771 In Treating Postoperative Dental Pain
Status: COMPLETED
Conditions: Postoperative Dental Pain
Interventions: DRUG: PF-05089771|OTHER: Placebo|DRUG: PF-05089771|OTHER: Placebo|DRUG: PF-05089771|OTHER: Placebo|DRUG: Ibuprofen|OTHER: Placebo|OTHER: Placebo|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Concurrent Chemoradiotherapy for Potentially Resectable Adenocarcinoma of the Esophagogastric Junction
Status: COMPLETED
Conditions: Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Oxaliplatin; Capecitabine|OTHER: Oxaliplatin; Capecitabine; concurrent radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mental Training for Adults With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Aging
Interventions: BEHAVIORAL: Mindfulness|BEHAVIORAL: Brain Games and Puzzles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided vs Unguided Intra-articular Knee Injections
Status: WITHDRAWN
Conditions: Osteoarthritis|Inflammatory Arthritis
Interventions: DEVICE: Ultrasound machine|DEVICE: Unguided injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Non-pharmacological Interventions for Dementia Prevention in Elderly Patients With Mild Cognitive Impairment
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment|Dementia Prevention
Interventions: OTHER: Home-based cognitive training exercises|OTHER: Supervised cognitive training exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Double Blinded Placebo Controlled Study on the Effects of Dietary Supplementation With a Probiotic on Stroke Patients
Status: UNKNOWN
Conditions: Stroke, Ischemic|Dysbiosis
Interventions: DIETARY_SUPPLEMENT: OMNi-BiOTiC SR-9|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: AZD9291, an Irreversible EGFR-TKI, in Relapsed EGFR-mutated Non-small Cell Lung Cancer Patients Previously Treated With an EGFR-TKI, Coupled to Extensive Translational Studies
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer|Targeted Therapy
Interventions: DRUG: AZD9291
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Grid Therapy for Tumors of the Head, Neck, Thorax, Abdomen, Pelvis and Extremities.
Status: COMPLETED
Conditions: Radiation Therapy Complication|Tumor Neck|Tumor Abdomen
Interventions: RADIATION: Spatially Fractionated Radiation (GRID) Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating Fluid Strategies in Thoracic Surgery Patients Utilizing a Goal Directed Approach
Status: COMPLETED
Conditions: Hypotension|Kidney Injury
Interventions: DRUG: Plasmalyte 3ml/kg/hr group|DRUG: Plasmalyte 6ml/kg/hr group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of COMP360 in Participants With Recurrent Major Depressive Disorder
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AGN-229666 Ophthalmic Solution in Japanese Patients With Allergic Conjunctivitis
Status: COMPLETED
Conditions: Conjunctivitis, Allergic
Interventions: DRUG: AGN-229666|DRUG: Vehicle to AGN-229666|DRUG: Olopatadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Guo's Visceral Arteries Reconstruction :The First in Man Study of WeFlow-JAAA Stent Graft System
Status: UNKNOWN
Conditions: Juxta Renal Abdominal Aortic Aneurysm Without Rupture
Interventions: DEVICE: WeFlow-JAAA Stent Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib (PS-341) in Combination With Carboplatin and Docetaxel for Patients With Advanced Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Bortezomib|DRUG: Carboplatin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Telapristone Acetate (Proellex®) Administered Vaginally for the Treatment of Uterine Fibroids
Status: COMPLETED
Conditions: Uterine Fibroids
Interventions: DRUG: Placebo|DRUG: Telapristone Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT