pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Massage Therapy in Treating Patients With Cancer Pain
Status: COMPLETED
Conditions: Pain|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: OTHER: massage therapy|OTHER: visit with a volunteer|OTHER: period of quiet time|BEHAVIORAL: questionaire about pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Learning Curve of Transurethral Holmium Laser Enucleation of the Prostate, Prospective Assessment
Status: RECRUITING
Conditions: Learning Curve|Laser|Prostate Hyperplasia
Interventions: PROCEDURE: Holmium laser enucleation of the prostate using the veil-sparing technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Early Administration of Botox® in Neuropathic Pain Due to Thoracoscopy or Thoracotomy
Status: WITHDRAWN
Conditions: Pain Due to Certain Specified Procedures|Neuropathic Pain
Interventions: DRUG: BOTOX|OTHER: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Home-based Action Observation Treatment With Virtual-reality for Arm Rehabilitation in People With Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: Home-based Action Observation Treatment with virtual-reality for upper limb rehabilitation|OTHER: Home-based landscape observation with virtual-reality for upper limb rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy of Actinic Keratosis of the Face and Scalp With and Without Prior Curettage
Status: COMPLETED
Conditions: Keratosis, Actinic
Interventions: DRUG: No curettage|DRUG: Curettage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Theraworx Foam in Carpal Tunnel Syndrome
Status: WITHDRAWN
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: Theraworx Foam|DRUG: Placebo Foam|OTHER: Theraworx Foam and night splint|OTHER: Placebo Foam and night time splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Localized Analysis of Normalized Distance From Scalp to Cortex and Personalized Evaluation (LANDSCAPE)
Status: ENROLLING_BY_INVITATION
Conditions: Aging|Dementia Alzheimers|Parkinson Disease|Dementia Frontotemporal|Depression in Old Age
Interventions: DEVICE: Transcranial Magnetic Stimulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Telerehabilitation and Face-to-Face Clinical Pilates-Based Exercise in Individuals With Axial Spondyloarthritis
Status: RECRUITING
Conditions: Axial Spondyloarthritis|Ankylosing Spondylitis
Interventions: OTHER: Clinical Pilates-Based Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib and 5-Azacitidine in Acute Leukemia + Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Azacitidine|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mastery Learning in Communication Skills
Status: NOT_YET_RECRUITING
Conditions: Communication Research|Communication, Personal|Burnout, Professional
Interventions: BEHAVIORAL: Mastery learning in communication skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: to Compare the Pharmacokinetics and Safety of Fimasartan/Rosuvastatin Combination Tablet and Coadministration of Fimasartan and Rosuvastatin
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Fimasartan|DRUG: Rosuvastatin|DRUG: Fimasartan/Rosuvastatin combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Ultrasound-Assisted Lumbar Puncture
Status: TERMINATED
Conditions: Spinal Puncture|Diagnostic Imaging
Interventions: PROCEDURE: Point-of-care ultrasound|PROCEDURE: Traditional Landmark-based Lumbar Puncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Toxicity Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer (Phase 1b)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-muscle Invasive Bladder Cancer
Interventions: BIOLOGICAL: TARA-002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Intrapartum Sims Position-related Efficiency in Correction of Persistent Foetal OP Positions
Status: UNKNOWN
Conditions: Persistent Occiput Posterior Position During Labor
Interventions: PROCEDURE: maternal modified sims position|PROCEDURE: maternal free positions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Ketamine Associate With an Opioid for Sedation in ICU
Status: COMPLETED
Conditions: Sedation for Mechanical Ventilation
Interventions: DRUG: Rémifentamil + KETAMINE|DRUG: ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Drug-drug Interaction Between Clopidogrel and Fluoxetine
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Clopidogrel then fluoxetine+clopidogrel|DRUG: Fluoxetine+clopidogrel then clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Antinociceptive Effect of Transauricular Electrical Vagal Nerve Stimulation
Status: UNKNOWN
Conditions: Pain, Acute
Interventions: DEVICE: TENS eco 2 Transauricular vagal nerve stimulation|DEVICE: Sham TENS eco 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparisons of Novel Double-lumen Endobronchial Tube for Blind Lung Isolation Technique With Conventional Double-lumen Endobronchial Tube in Patients Undergoing One-lung Ventilation
Status: COMPLETED
Conditions: Intubation Tube(Intubation Using Double Lumen Endobronchial Tube)
Interventions: DEVICE: Endobronchial intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Effect of Video Education on Pain, Anxiety and Knowledge Levels of Coronary Bypass Graft Surgery Patients
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: OTHER: Coronary bypass graft surgery video education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study on the Efficacy of Autologous Cell Factor Induced Killer Cells in the Treatment of Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: COMBINATION_PRODUCT: CIK combined with chemotherapy group|COMBINATION_PRODUCT: CIK combined immunotherapy group|COMBINATION_PRODUCT: CIK combined targeted therapy group|COMBINATION_PRODUCT: CIK in combination with other therapies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Multidomain Non-pharmacological Interventions on the Elderly With or Without Mild Cognitive Impairment
Status: ACTIVE_NOT_RECRUITING
Conditions: Mild Cognitive Impairment|The Cognitive Normal Elderly
Interventions: BEHAVIORAL: the multimodal intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of Norovirus GI.1/GII.4 Bivalent Virus-Like Particle Vaccine in an Elderly Population
Status: COMPLETED
Conditions: Norovirus
Interventions: BIOLOGICAL: Norovirus GI.1/GII.4 Bivalent VLP Vaccine|DRUG: 0.9% sodium chloride (saline)|BIOLOGICAL: Norovirus GI.1/GII.4 Bivalent VLP Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High Dose Oral Versus Intramuscular Vitamin D3 Supplementation In Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Placebo-Controlled Study of MK0634 in Patients With Overactive Bladder (0634-007)
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DRUG: MK-0634 50 mg|DRUG: MK-0634 125 mg|DRUG: Placebo for MK-0634
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality: a Teaching-learning Strategy for Cognitive Mastery in Airway Trauma Management
Status: RECRUITING
Conditions: Education, Medical|Airway Management|Students, Medical|Virtual Reality|Trauma Centers|Manikins
Interventions: OTHER: VR-based simulation|OTHER: Mannequin-based simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Treatment With Indinavir and Chemotherapy for Advanced Classical Kaposi's Sarcoma
Status: COMPLETED
Conditions: Kaposi's Sarcoma
Interventions: DRUG: Indinavir in association with Vinblastina +/- Bleomicina
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess Efficacy of Epiitalis on Knee Pain in Patients Suffering From Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Epiitalis|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Trigger Finger Preference Elicitation Tool
Status: TERMINATED
Conditions: Trigger Finger|Trigger Thumb|Trigger Digit|Trigger Finger Disorder|Trigger Thumb, Left Thumb|Trigger Thumb, Right Thumb|Trigger Finger, Ring Finger|Trigger Finger, Index Finger|Trigger Finger, Middle Finger|Trigger Finger, Little Finger|Trigger Thumb, Unspecified Thumb|Trigger Finger, Unspecified Finger
Interventions: OTHER: Preference elicitation tool|OTHER: handout
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase II Sorafenib With Radiation and Temozolomide in Newly Diagnosed Glioblastoma or Gliosarcoma
Status: WITHDRAWN
Conditions: Glioblastoma|Gliosarcoma
Interventions: DRUG: Temozolomide|RADIATION: Radiation|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Ropinirole in Motor Recovery After Stroke
Status: COMPLETED
Conditions: Cerebrovascular Accident|Hemiparesis
Interventions: DRUG: Ropinirole (+ physical therapy)|DRUG: (vs.) Placebo + physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Activation and Satiety in Children 2
Status: ACTIVE_NOT_RECRUITING
Conditions: Childhood Obesity
Interventions: BEHAVIORAL: Family Based Behavioral Treatment|DRUG: Exenatide 2 mg [Bydureon]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: INTERVENE: Indian Trial of Endocardial Ventricular Substrate Ablation to Prevent Recurrent VT Events
Status: TERMINATED
Conditions: Ventricular Tachycardia
Interventions: DRUG: Amiodarone|DEVICE: Catheter Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 24 Vs 48 Hours of Cefazolin or Cefuroxime as Prophylaxis
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: DRUG: Cefuroxime|DRUG: Cefazolin|OTHER: 24 hours|OTHER: 48 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RGI-2001 for the Prevention of Acute Graft-vs-Host Disease in Subjects Following Allogeneic Hematopoietic Stem Cell Transplantation
Status: COMPLETED
Conditions: Graft Vs Host Disease|Graft-versus-host-disease|Acute-graft-versus-host Disease|Prevention of aGVHD
Interventions: DRUG: RGI-2001|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Long-term Safety and Efficacy of Deucravacitinib in Participants With Crohn's Disease or Ulcerative Colitis
Status: COMPLETED
Conditions: Crohn Disease|Ulcerative Colitis
Interventions: DRUG: Deucravacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise and Diet Program for Schizophrenia Patients Who Are Taking Atypical Antipsychotic Medications
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Exercise program|BEHAVIORAL: Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Tipifarnib in Head and Neck Cancer With HRAS Mutations and Impact of HRAS on Response to Therapy
Status: COMPLETED
Conditions: HRAS Gene Mutation|HNSCC
Interventions: DRUG: Tipifarnib|DEVICE: HRAS Detection Assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Comparative Effectiveness of Liberal Versus Restricted Maternal Administration of Oxygen During Labor
Status: COMPLETED
Conditions: Maternal Oxygen Use in Labor
Interventions: DRUG: Liberal use of maternal oxygen|DRUG: Indicated use of maternal oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plyometric and Eccentric Training in Improving the Strength, Stability and Ability of Women Soccer Players
Status: COMPLETED
Conditions: Female Athlete
Interventions: OTHER: Leg Squat Lounge|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NIVolumab in Subjects With Recurrent or Metastatic Platinum-refrACTORy SCCHN
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: Nivolumab 240 MG in 24 ML Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of ANK-700 in Patients With Relapsing Remitting Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis (MS)|Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: ANK-700|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of High Dose Vitamin D Supplementation for Overactive Bladder Dry in Children
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Solifenacin Succinate 5 MG Oral Tablet [Vesicare]|DRUG: Vitamin D3|BEHAVIORAL: Standard urotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Melatonin Treatment for Tardive Dyskinesia in Schizophrenia
Status: COMPLETED
Conditions: Tardive Dyskinesia
Interventions: DRUG: Melatonin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Strategies and Survival Outcome for Non-small Cell Lung Cancer With Oncogenic Mutation
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|EGFR Gene Mutation|ALK Gene Mutation|ROS1 Gene Mutation|MET Gene Mutation
Interventions: DRUG: Osimertinib|DRUG: Alectinib 150 MG|DRUG: Crizotinib 250 MG|DRUG: Savolitinib, Crizotinib.|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of an Investigational Multi-Purpose Solution on Lens Moisture
Status: COMPLETED
Conditions: Contact Lens Moisture
Interventions: DEVICE: FID 114675A Multi-Purpose Disinfecting Solution (MPDS)|DEVICE: ReNu Fresh Lens Comfort Multi-Purpose Solution (MPS)|DEVICE: Silicone Hydrogel Contact Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Antibiotic Prophylaxis in Elective Laparoscopic Colorectal Surgery: Oral and Systemic Versus Systemic Antibiotics
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: cefmetazole|DRUG: kanamycin/metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Safety, Tolerability, Pharmacokinetics of E2027 in Healthy Adult and Elderly Subjects, and the Pharmacodynamics in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: E2027|DRUG: E2027 matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Network Modulation in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease|Primary Progressive Aphasia|Mild Cognitive Impairment
Interventions: DEVICE: repetitive transcranial magnetic stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Prone Positioning on Mortality in Patients With Mild to Moderate Acute Respiratory Distress Syndrome.
Status: RECRUITING
Conditions: ARDS|Acute Respiratory Distress Syndrome|Intensive Care Unit|Mechanical Ventilation
Interventions: PROCEDURE: Patients will receive MV in PP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Applicability of Different Scoring Systems and Use of Steroids in the Treatment of Hospital Acquired Pneumonia
Status: UNKNOWN
Conditions: Pneumonia Hospital Acquired
Interventions: DRUG: Prednisone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Treatment on Iatrogenic Weight Gain and Dyslipidaemia Associated With Olanzapine
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: GWP42003 : GWP42004 (40:1)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sphenopalatine Ganglion Block for Management of Post- Dural Puncture Headache in Obstetric Patients
Status: COMPLETED
Conditions: Post-Dural Puncture Headache
Interventions: PROCEDURE: Sphenopalatine ganglion block|DRUG: paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adavosertib Plus Chemotherapy in Platinum-Resistant Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian, Fallopian Tube, Peritoneal Cancer, P53 Mutation
Interventions: DRUG: Adavosertib|DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Gemcitabine|DRUG: PLD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pasireotide s.c. in Patients With Post-Bariatric Hypoglycaemia
Status: RECRUITING
Conditions: Post-Bariatric Hypoglycemia
Interventions: DRUG: Pasireotide Diaspartate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis|Nervous System Diseases|Sclerosis|Motor Neuron Disease|Spinal Cord Diseases|Central Nervous System Diseases|Neurodegenerative Diseases|Neuromuscular Diseases|ALS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of an Active Pulsed Electromagnetic Field for the Treatment of Osteoarthritis of the Knee
Status: TERMINATED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Orthofix Physio-Stim Model 3315OA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Haplo-identical Transplantation in Patients With Myelofibrosis - A Phase 2 Prospective Multicentric Prospective Study
Status: UNKNOWN
Conditions: Myelofibrosis
Interventions: OTHER: Allogenic transplantation transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Yoga Therapy in Rehabilitation Compared to Physiotherapy in Moderate Axial Spondyloarthritis (axSPA)
Status: NOT_YET_RECRUITING
Conditions: Axial Spondyloarthritis (axSPA)
Interventions: PROCEDURE: Yogatherapy|PROCEDURE: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and Cisplatin for Thymic Neoplasm
Status: TERMINATED
Conditions: Thymoma|Thymic Carcinoma
Interventions: DRUG: paclitaxel and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of EXPAREL in Patients Undergoing Breast Augmentation
Status: COMPLETED
Conditions: Mammoplasty|Postoperative Pain
Interventions: DRUG: Instillation - EXPAREL|DRUG: Infiltration - EXPAREL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Intravitreal Injections of Anti-VEGF as Initial and Adjuvant Treatment in Coats Disease
Status: SUSPENDED
Conditions: Retinal Telangiectasis|Coats Disease
Interventions: DRUG: Anti-VEGF injections of bevacizumab|DEVICE: Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fed Study of Chlorpheniramine Polistirex and Hydrocodone Polistirex Capsules and Tussionex® Pennkinetic® Extended Release Oral Suspension
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Chlorpheniramine polistirex equivalent to 8 mg of chlorpheniramine maleate and hydrocodone polistirex equivalent to 10 mg of hydrocodone bitartrate capsule|DRUG: 5 mL chlorpheniramine (8 mg/5 mL)/hydrocodone (10 mg/5 mL) extended release oral suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Nicotinamide Riboside Clinical Trial for GWI
Status: RECRUITING
Conditions: Gulf War Illness
Interventions: DIETARY_SUPPLEMENT: Nicotinamide Riboside|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dexamethasone and Ondansetron Versus Placebo for Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Dexamethasone and Ondansetron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics of Gepotidacin Tablets in Adults and Adolescents Subjects
Status: COMPLETED
Conditions: Infections, Bacterial
Interventions: DRUG: Gepotidacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of QL1706 Injection in Patients With Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: QL1706 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab With or Without Bevacizumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage IIIC Cutaneous Melanoma AJCC v7|Stage IV Cutaneous Melanoma AJCC v6 and v7|Unresectable Melanoma
Interventions: BIOLOGICAL: Bevacizumab|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Study to Evaluate AMG 579 in Healthy Subjects and Patients With Stable Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: AMG 579|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of a Combination Product [Drug:BCI-024 (Buspirone) and Drug:BCI-049 (Melatonin)] to Treat Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: BCI-024: over-encapsulated Buspirone tablet 15 mg QD and BCI-049: over-encapsulated Melatonin tablet 3 mg QD|DRUG: BCI-024 (Buspirone)|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Functional Vision Provided by AMO Tecnis Z9000 and Alcon SA60AT Acrysof
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: aspherical intraocular lens|DEVICE: spherical intraocular lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Tenofovir Disoproxil Fumarate on Lipid Levels in HIV Infected Adults on Stable Anti-HIV Drug Therapy
Status: COMPLETED
Conditions: HIV Infections|Dyslipidemia|Hyperlipidemia|Hypercholesterolemia|Hypertriglyceridemia
Interventions: DRUG: Tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Phenotype-Based,Capillary Refill Time-Targeted Resuscitation In Early Septic Shock:ANDROMEDA-SHOCK-2
Status: RECRUITING
Conditions: Intensive Care Unit Acquired Weakness|Shock, Septic
Interventions: OTHER: Usual care (UC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Whole Genome Sequencing Versus Whole Exome Sequencing for Congenital Diarrhea and Enteropahty
Status: RECRUITING
Conditions: Diarrhea, Infantile|Enteropathy
Interventions: GENETIC: Whole genome sequencing|GENETIC: Whole exome sequencing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of LY3938577 in Healthy Participants and Participants With Type 1 Diabetes Mellitus (T1DM)
Status: RECRUITING
Conditions: Healthy|Type 1 Diabetes Mellitus
Interventions: DRUG: LY3938577|DRUG: Placebo|DRUG: Insulin Degludec|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lenvatinib, Pembrolizumab, and Tumor Treating Fields (TTFields) for Second-line Treatment of Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: GBM
Interventions: DRUG: Lenvatinib|DRUG: Pembrolizumab|DEVICE: Tumor Treating Fields (TTFields)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Vigadexa in Treating Inflammation and Infection Post-cataract Surgery
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Vigadexa (moxifloxacin 0.5% and dexamethasone 0.1%) eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Alveolar Macrophages in Healthy Individuals Versus Individuals With COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Lung Diseases, Obstructive
Interventions: PROCEDURE: blood drawing|PROCEDURE: fiberoptic bronchoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A 4-Week Study of the Safety, Efficacy, and Pharmacokinetics of JZP-110 [(R)-2-amino-3-phenylpropylcarbamate Hydrochloride] in Subjects With Parkinson's Disease and Excessive Sleepiness
Status: COMPLETED
Conditions: Excessive Sleepiness|Parkinson Disease
Interventions: DRUG: JZP-110|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Safety and Efficacy of Favipiravir (Favipira) for COVID-19 Patient in Selected Hospitals of Bangladesh
Status: UNKNOWN
Conditions: COVID-19|Favipiravir (Favipira)
Interventions: DRUG: Favipiravir|DRUG: Only Standard Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Controlled Study of the Effectiveness of Oregovomab (Antibody) Plus Chemotherapy in Advanced Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasms
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|BIOLOGICAL: oregovomab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expansion of Conventional Criteria for Liver Transplantation in Hepatocellular Carcinoma Through Downstaging
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular|Cirrhosis
Interventions: PROCEDURE: Liver transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glutamatergic Modulation as a Treatment for Depressive Symptoms Among Patients With Post-acute Sequelae of COVID (PASC): A Pilot Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Post-acute Sequelae of COVID-19|Depressive Symptoms|Cognitive Dysfunction
Interventions: DRUG: CI-581a|DRUG: CI-581b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme
Status: COMPLETED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Tumor
Interventions: DRUG: vorinostat|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-enrolment and Non-adherence to HIV Care in a Community-based Program, Rakai, Uganda
Status: COMPLETED
Conditions: CD4 Deficiency|Adherence|Quality of Life
Interventions: OTHER: patient-selected care buddy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Efficacy and Safety of Tender Point Infiltration (TPI) for Acute and Subacute Zoster Associated Pain
Status: RECRUITING
Conditions: Herpes Zoster|Local Infiltration|Acute Pain
Interventions: DRUG: analgesic|BEHAVIORAL: Tender point infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lipografting Versus Steroid Injections for Treatment of Carpal Tunnel Syndrome
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Fat Injection|DRUG: Steroid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SU5416 in Treating Patients With Metastatic Melanoma That Has Been Previously Treated
Status: TERMINATED
Conditions: Recurrent Melanoma|Stage IV Melanoma
Interventions: DRUG: semaxanib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Dosage of a Computerized Cognitive Training Program for Cognitive Dysfunction After COVID-19
Status: NOT_YET_RECRUITING
Conditions: Post-Acute COVID-19|Post Acute COVID-19 Syndrome|Cognitive Dysfunction|Cognitive Impairment
Interventions: BEHAVIORAL: CCT Long COVID
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Steroids, Thiamine and Ascorbic Acid in Septic Shock
Status: UNKNOWN
Conditions: Septic Shock
Interventions: DRUG: STASIS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Benefit of Lumbar Bracing for Chronic Low Back Pain Due to Degenerative Disc Disease
Status: COMPLETED
Conditions: Degenerative Disc Disease|Lumbar Spondylosis|Low Back Pain
Interventions: OTHER: Lumbar back brace|BEHAVIORAL: Back school
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adrenaline Solution Irrigation and Bleeding During Sinus Surgery
Status: COMPLETED
Conditions: Chronic Rhinosinusitis (Diagnosis)
Interventions: DRUG: Adrenaline saline irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Regional Kale as Source of Lutein and Zeaxanthin to Improve Vision of AMD-patients
Status: UNKNOWN
Conditions: Changes in Macular Pigment Optical Density
Interventions: DIETARY_SUPPLEMENT: S1: Dosage-dependency|OTHER: S2: Kale extract versus kale purée|OTHER: S3: Kale extract: AMD-patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Does the Rapid Intravenous Administration of Oxytocin After Delivery of the Baby Decrease the Bleeding During Cesarean Section in Women at Risk of Bleeding During Cesarean Section?
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Oxytocin|DRUG: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Sulphadoxine-pyrimethamine and Amodiaquine in Ghanaian Pregnant Women
Status: COMPLETED
Conditions: Malaria|Pregnancy
Interventions: DRUG: Amodiaquine|DRUG: Sulphadoxine-pyrimethamine|DRUG: Chloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Open Label Study Of SU011248 In Combination With Trastuzumab For Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: SU011248/Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Surgical Treatment of Osteomyelitis in Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Osteomyelitis|Diabetic Foot|Diabetic Foot Ulcers
Interventions: PROCEDURE: Conservative surgery|DRUG: Ciprofloxacin|DRUG: Amoxicillin-Potassium Clavulanate Combination|DRUG: Sulfamethoxazole trimethoprim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Therapy for Recurrent Low Back Pain: Unraveling the Puzzle of Peripheral Muscle and Central Brain Changes
Status: RECRUITING
Conditions: Low Back Pain, Recurrent
Interventions: BEHAVIORAL: Specific skilled motor training|BEHAVIORAL: General extension training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of CYT004-MelQbG10 Vaccine With and Without Adjuvant in Advanced Stage Melanoma Patients
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: BIOLOGICAL: CYT004-MelQbG10 + Montanide|BIOLOGICAL: CYT004-MelQbG10 + Montanide + Imiquimod|BIOLOGICAL: CYT004-MelQbG10 + Imiquimod|BIOLOGICAL: CYT004-MelQbG10 intra nodal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Clinical Trial to Evaluate the Efficacy and Safety of ZKY001 Eye Drops
Status: COMPLETED
Conditions: Corneal Epithelium Defect
Interventions: DRUG: lowe-dose ZKY001 eye drops|DRUG: Medium-dose ZKY001 eye drops|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cell Therapy for Lower Limb Ulcers in Patients With Critical Limb Ischemia
Status: NOT_YET_RECRUITING
Conditions: Peripheral Arterial Disease|Leg Ulcer
Interventions: BIOLOGICAL: CELULAS TRONCO|DEVICE: CONVENTIONAL DRESSING
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Abbreviated Chemotherapy Based on Positron Emission Tomography (PET) Scan in Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Hodgkin's Lymphoma
Interventions: DRUG: ABVD chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3DKnee™ System vs. the MJS Knee System
Status: TERMINATED
Conditions: Rheumatoid Arthritis|Traumatic Arthritis|Joint Disease Secondary to Osteoarthritis
Interventions: DEVICE: Encore 3DKnee™ system|DEVICE: Encore MJS™ Knee System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Comparing the Gastro-intestinal Tolerability and Absorption Profile of Vortioxetine After Administration of Modified-release Formulations and Immediate-release Formulation in Healthy Women
Status: COMPLETED
Conditions: Healthy Women
Interventions: DRUG: Encapsulated vortioxetine IR tablet, 20 mg|DRUG: Vortioxetine MR capsule 20 mg (pH 5.5)|DRUG: Vortioxetine MR capsule 20 mg (pH 6.0)|DRUG: Vortioxetine MR capsule 20 mg (pH 7.0)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Modified Reporting of Positive Urine Cultures Collected From Long Term Care
Status: COMPLETED
Conditions: Urinary Tract Infections|Asymptomatic Bacteriuria
Interventions: BEHAVIORAL: Modified Report
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Impact of High-level Oxygen Therapy on the Reconditioning of Type I Hypoxemic Respiratory Insufficiency Patients in Intensive Care
Status: COMPLETED
Conditions: Hypoxemic Respiratory Failure
Interventions: DEVICE: Cyclometer Ergometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of DIAbetic RETinopathy and Impact of Genetic Factors in the Development of Diabetic Retinopathy of Patients With Type 1 and 2 Diabetes Mellitus in SlovaKia
Status: COMPLETED
Conditions: Diabetic Retinopathy|Diabetic Macular Edema|Diabetes Mellitus
Interventions: GENETIC: Studied cohort
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BurtVision™ for Arm Rehabilitation in Chronic Stroke Survivors:
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: DEVICE: Burt|DEVICE: Burt + BurtVision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: KYSA-5: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Systemic Sclerosis
Status: RECRUITING
Conditions: Systemic Sclerosis|Systemic Sclerosis - Diffuse Cutaneous|Systemic Sclerosis - 2013 ACR/EULAR Classification Criteria
Interventions: BIOLOGICAL: KYV-101|DRUG: Standard lymphodepletion regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leukocyte-rich PRP or Leukocyte-free PRP vs Placebo in the Treatment of Epicondylitis
Status: RECRUITING
Conditions: Tennis Elbow
Interventions: BIOLOGICAL: Injection of autologous leukocyte rich platelet rich plasma (LR-PRP)|BIOLOGICAL: Injection of autologous leukocyte poor platelet rich plasma (LP-PRP)|DRUG: Placebo (saline solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Fluence Light Emitting Diode-Red Light (LED-RL) in Human Skin
Status: COMPLETED
Conditions: Fibrosis|Scarring|Scar|Wounds|Injuries|Keloid|Cicatrix|Hypertrophic
Interventions: DEVICE: LED-RL Phototherapy|DEVICE: Mock Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Salmeterol/Fluticasone 50/500 mcg Inhalation Powder Via Capsair vs Seretide Diskus 500 mcg Inhalation Powder in Patients With COPD
Status: TERMINATED
Conditions: COPD
Interventions: DRUG: Salmeterol/Fluticasone Capsair®|DRUG: Salmeterol/Fluticasone Diskus®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Evaluation of an Ultra Conservative Approach to Implantable Defibrillator (ICD) Programming in Patients With a Left Ventricular Assist Device (LVAD).
Status: COMPLETED
Conditions: Heart Failure
Interventions: OTHER: Ultra Conservative ICD Programming|OTHER: Traditional ICD Programming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Preventing Acquired Resistance: Strengthen TB Treatment by Adding Amikacin in the First Treatment Week of Multidrug-resistant Tuberculosis
Status: RECRUITING
Conditions: Tuberculosis, Multidrug-Resistant
Interventions: DRUG: Amikacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Entinostat, Lapatinib Ditosylate and Trastuzumab in Treating Patients With Locally Recurrent or Distant Relapsed Metastatic Breast Cancer Previously Treated With Trastuzumab Only
Status: COMPLETED
Conditions: HER2/Neu Positive|Invasive Breast Carcinoma|Recurrent Breast Carcinoma|Stage IV Breast Cancer AJCC v6 and v7
Interventions: DRUG: Entinostat|OTHER: Laboratory Biomarker Analysis|DRUG: Lapatinib Ditosylate|BIOLOGICAL: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Rasagiline in Restless Legs Syndrome
Status: TERMINATED
Conditions: Restless Legs Syndrome
Interventions: DRUG: rasagiline|DRUG: placebo (sugar pill)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical, Biochemical and Neurophysiological Consequences of Intraoperative Tourniquet During Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Muscles Ischemia
Interventions: PROCEDURE: Total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Pezzi Ball on Balance in Pregnant Women
Status: COMPLETED
Conditions: Postural Stability
Interventions: OTHER: proprioceptive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE