pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Assessment of Postoperative Pain and Bacterial Load Reduction After Using TruNatomy and ProTaper Next Rotary Systems in Patients With Necrotic Mandibular Molars: A Randomized Clinical Trial
Status: UNKNOWN
Conditions: Endodontic Treatment
Interventions: DEVICE: mechanical instrumentation using rotary file system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erythropoietin + Iron Therapy for Anemic Patients Undergoing Aortic Valve Replacement
Status: COMPLETED
Conditions: Anemia|Aortic Stenosis
Interventions: DRUG: Erythropoietin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RESTORE in Patients Who Had COVID-19 and Close Others
Status: UNKNOWN
Conditions: Mental Health|PTSD|Anxiety|Depressive Symptoms
Interventions: BEHAVIORAL: RESTORE: Recovering from Extreme Stressors Through Online Resources and E-health
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PROUD Study: A Prospective Study on the Usage Patterns of Doripenem in the Asia Pacific Region
Status: COMPLETED
Conditions: Pneumonia|Pneumonia, Ventilator-Associated|Urinary Tract Infections
Interventions: DRUG: doripenem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Dose Finding Trial of BM32 in Subjects Suffering From Grass Pollen Allergy
Status: COMPLETED
Conditions: Grass Pollen Allergy
Interventions: BIOLOGICAL: BM32|BIOLOGICAL: BM32|BIOLOGICAL: BM32|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TCR Genetically Engineered PBMC and PBSC After Melphalan Conditioning Regimen in Treating Participants With Relapsed and Refractory Multiple Myeloma
Status: WITHDRAWN
Conditions: HLA-A*0201 Positive Cells Present|NY-ESO-1 Positive Tumor Cells Present|Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: RADIATION: 18F-FHBG|BIOLOGICAL: Aldesleukin|BIOLOGICAL: Cellular Therapy|PROCEDURE: Computed Tomography|BIOLOGICAL: Filgrastim|OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|PROCEDURE: Leukapheresis|DRUG: Melphalan|DRUG: Plerixafor|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GS-9674 (Cilofexor), and the Effect of Food on GS-9674 Pharmacokinetics and Pharmacodynamics
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis (NASH)
Interventions: DRUG: Cilofexor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FST-201 In The Treatment of Acute Otitis Externa
Status: TERMINATED
Conditions: Acute Otitis Externa
Interventions: DRUG: FST-201 (dexamethasone 0.1%) Otic Suspension|DRUG: ciprofloxacin 0.3%, dexamethasone 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Scleroligation for Eradication of Gastroesophageal Varices.
Status: UNKNOWN
Conditions: Gastroesophageal Varices
Interventions: PROCEDURE: Sclerotherapy|PROCEDURE: Band ligation|PROCEDURE: Scleroligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study Between Fluticasone Salmeterol Xinafoate vs. ADVAIR DISKUS® in Healthy Volunteers
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Fluticasone propionate 500 mcg and salmeterol xinafoate 50 mcg|DRUG: ADVAIR DISKUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Enhanced vs. Routine Clear Liquid Intake in Labor
Status: COMPLETED
Conditions: Abnormal Labor|Failed Induction of Labor|Ketosis
Interventions: DIETARY_SUPPLEMENT: Accel Gel|DIETARY_SUPPLEMENT: Usual clear diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Aerobic Exercise for Remyelination in Multiple Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis|Sclerosis|Demyelinating Diseases|Autoimmune Diseases of the Nervous System|Nervous System Diseases|Demyelinating Autoimmune Diseases, CNS|Exercise
Interventions: BEHAVIORAL: Aerobic exercise|BEHAVIORAL: Education Group Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Efficacy and Safety of Front-line Fludarabine, Cyclophoshamide and Ofatumumab Chemoimmunotherapy in Young Patients With Chronic Lymphocytic Leukemia.
Status: COMPLETED
Conditions: B-cell Lymphoid Leukemia|Young Patients
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Ofatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dietary Supplements for Pregnant Women on Levothyroxine Absorption
Status: UNKNOWN
Conditions: Hypothyroidism Primary
Interventions: DIETARY_SUPPLEMENT: Prenatal Nutrients Solgar|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Adults With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), and/or With Severe Hypertriglyceridemia
Status: COMPLETED
Conditions: Hypertriglyceridemia|Atherosclerotic Cardiovascular Disease|Severe Hypertriglyceridemia
Interventions: DRUG: Olezarsen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin and Nivolumab in Treating Patients With Early Stage Classic Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Ann Arbor Stage I Hodgkin Lymphoma|Ann Arbor Stage I Mixed Cellularity Classic Hodgkin Lymphoma|Ann Arbor Stage I Nodular Sclerosis Classic Hodgkin Lymphoma|Ann Arbor Stage IA Hodgkin Lymphoma|Ann Arbor Stage IB Hodgkin Lymphoma|Ann Arbor Stage II Hodgkin Lymphoma|Ann Arbor Stage IIA Hodgkin Lymphoma|Ann Arbor Stage IIB Hodgkin Lymphoma|Classic Hodgkin Lymphoma|Lymphocyte-Rich Classic Hodgkin Lymphoma|Ann Arbor Stage I Lymphocyte-Depleted Classic HL|Ann Arbor Stage II Lymphocyte-Depleted Classic HL|Ann Arbor Stage II Mixed Cellularity Classic HL|Ann Arbor Stage II Nodular Sclerosis Classic HL
Interventions: DRUG: Bleomycin|DRUG: Brentuximab Vedotin|DRUG: Dacarbazine|DRUG: Doxorubicin|BIOLOGICAL: Nivolumab|OTHER: Quality-of-Life Assessment|DRUG: Vinblastine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PH94B Nasal Spray for Anxiety Induced by a Public Speaking Challenge
Status: COMPLETED
Conditions: Social Anxiety Disorder
Interventions: DRUG: PH94B Nasal Spray|DRUG: Placebo Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Metabolic Effects of Ginseng Oligopeptide Preparation on Non- Alcoholic Fatty Liver Disease With Obesity: a Randomized Controlled Double-blind Trial
Status: NOT_YET_RECRUITING
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: OTHER: Ginseng oligopeptide (Ginseng extract）|OTHER: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rifampicin Explorative PK Study for Tuberculous Meningitis Comparing Oral and Intravenous Preparation
Status: COMPLETED
Conditions: Tuberculous Meningitis
Interventions: DRUG: Rifampicin intravenous|DRUG: Oral rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Brain Stimulation to Improve Mobility in Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Dementia|Presenile Alzheimer Dementia|Aging
Interventions: OTHER: Personalized tDCS|OTHER: Active-Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Procrit Versus No Procrit in Acute Lymphocytic Leukemia, Lymphoblastic Lymphoma, or Burkitt's Undergoing Induction/Consolidation Chemotherapy
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Procrit (epoetin alfa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Elacytarabine (CP-4055) Plus Idarubicin as Second Course Remission-Induction Therapy in Patients With Acute Myeloid Leukaemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Elacytarabine plus idarubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concomitant HPV Vaccination and HPV Screening HPV Infection and Cervical Cancer in Sweden
Status: RECRUITING
Conditions: HPV Infection|CIN 2/3|Cervical Cancer
Interventions: BIOLOGICAL: Gardasil9
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ADDITION OF BISMUTH TO THE STANDARD TRIPLE THERAPY FOR HELICOBACTER PYLORI ERADICATION
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: ARM A Triple therapy for helicobacter pylori|DRUG: ARM B Quadruple therapy for helicobacter pylori
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tele-rehabilitation to Maintain Function and Health: COPD Patients on Bike to Paris
Status: RECRUITING
Conditions: Telerehabilitation|COPD|Quality of Life|Mobility Limitation
Interventions: OTHER: Home-based cycle-exercise for COPD patients|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cyanoacrylate Use in Free Gingival Graft
Status: COMPLETED
Conditions: Gingival Recession, Localized
Interventions: PROCEDURE: Free gingival graft|PROCEDURE: Cyanoacrylate|PROCEDURE: Suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infusion of Genetically Modified T Cell for Post Transplant Patients With Relapsed Disease
Status: COMPLETED
Conditions: Leukemia|Lymphoma, Non-Hodgkin|Hodgkin Disease|Myelodysplastic Syndromes|Multiple Myeloma
Interventions: GENETIC: CD34-TK75 transduced donor lymphocytes|RADIATION: Sub Study - 18 FHBG PET/CT Scans
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Head Position on MACEI of Sevoflurane in Children With Obstructive Airway
Status: UNKNOWN
Conditions: Sevoflurane|Endotracheal Intubation
Interventions: DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Patient's Perception of Treatment Outcome With Darifenacin by Patients With Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder (OAB)
Interventions: DRUG: Darifenacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial of Patient Decision Aids for Implantable Cardioverter-Defibrillators (ICDs)
Status: COMPLETED
Conditions: Systolic Heart Failure|Sudden Cardiac Death
Interventions: BEHAVIORAL: ICD Decision Aid Toolkit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Immunogenicity of SARS-CoV-2 Protein Subunit Recombinant Vaccine in Healthy Children
Status: RECRUITING
Conditions: Vaccine Reaction|Vaccine Adverse Reaction
Interventions: BIOLOGICAL: SARS-CoV-2 Protein Subunit Recombinant Vaccine|BIOLOGICAL: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Order of Movement on Nerve Root Function
Status: NOT_YET_RECRUITING
Conditions: Physical and Rehabilitation Medicine
Interventions: OTHER: standard neural mobilization|OTHER: Distal to proximal neural mobilization|OTHER: proximal to distal neural mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Tolerability, and Pharmacokinetic Study of TRK-250 for Patients With Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: TRK-250|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glycine and Oral D-Cycloserine in Alcoholic Patients and Healthy Subjects
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: D-Cycloserine PO and Glycine IV|DRUG: Placebo D-Cycloserine PO and placebo Glycine IV|DRUG: Placebo D-Cycloserine PO and Glycine IV|DRUG: D-Cycloserine PO and placebo Glycine IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase III Clinical Study of a SARS-CoV-2 Messenger Ribonucleic Acid (mRNA) Vaccine Candidate Against COVID-19 in Population Aged 18 Years and Above
Status: UNKNOWN
Conditions: COVID-19|SARS-CoV-2
Interventions: BIOLOGICAL: SARS-CoV-2 mRNA Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Plasma Biomarkers of Muscle Metabolism During Exercise to the Assessment of Insulin Resistance in CKD Dialysis Patients
Status: NOT_YET_RECRUITING
Conditions: Metabolic Syndrome|Dialysis; Complications
Interventions: DIAGNOSTIC_TEST: Exercise test|DIAGNOSTIC_TEST: Blood sample|DIAGNOSTIC_TEST: Impedancemetry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Proof of Concept Phase 2 Study to Evaluate the Safety and Efficacy of Clevudine in Patients With Mild and Moderate COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Clevudine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Intrathecal Nalbuphine as an Adjuvant to Subarachnoid Block on Postoperative Analgesia in Patients Undergoing Transurethral Resection of the Prostate
Status: NOT_YET_RECRUITING
Conditions: Transurethral Resection of Prostate
Interventions: DRUG: Nalbuphine Hydrochloride 10 MG/ML|DRUG: Sodium Chloride 0.9 % in 5 ML Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MK-3475A (Pembrolizumab Formulated With MK-5180) in Japanese Participants With Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma (R/M cSCC) or Locally Advanced (LA) Unresectable cSCC (MK-3475A-E39)
Status: RECRUITING
Conditions: Squamous Cell Carcinoma
Interventions: BIOLOGICAL: MK-3475A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Infusional Chemotherapy With the P-Glycoprotein Antagonist PSC 833
Status: COMPLETED
Conditions: Breast Cancer|Kidney Neoplasm|Lymphoma|Neoplasm Metastasis|Ovarian Cancer
Interventions: DRUG: PSC 833
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate The Effect Of Renal Impairment On The Pharmacokinetics Of PF-04991532
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Healthy
Interventions: DRUG: PF-04991532|DRUG: PF-04991532|DRUG: PF-04991532|DRUG: PF-04991532
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: SBRT With Immunotherapy in Early Stage Non-small Cell Lung Cancer: Tolerability and Lung Effects
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer Stage II|Non-small Cell Lung Cancer Stage I
Interventions: RADIATION: Stereotactic body radiotherapy|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Hydroxychloroquine in Patients With Inflammatory Cardiomyopathy
Status: RECRUITING
Conditions: Inflammatory Cardiomyopathy|Myocarditis
Interventions: DRUG: Hydroxychloroquine|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: R-ESHAP Followed by Autologous Transplantation for Refractory or Relapsed Diffused Large B-cell Lymphoma
Status: UNKNOWN
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: R-ESHAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Faricimab Treatment Response in Treatment-Naive, Underrepresented Patients With Diabetic Macular Edema
Status: RECRUITING
Conditions: Diabetic Macular Edema
Interventions: DRUG: Faricimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Destiffening and Hypotensive Effects of Whole Milk and Full-fat Dairy Products
Status: COMPLETED
Conditions: Hypertension|Prehypertension
Interventions: DIETARY_SUPPLEMENT: High fat dairy|DIETARY_SUPPLEMENT: Plant-based
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tissue Engineering Microtia Auricular Reconstruction: in Vitro and in Vivo Studies
Status: COMPLETED
Conditions: Microtia
Interventions: OTHER: Platelet-rich plasma (PRP)|OTHER: Chondrocyte culture with FBS medium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Significance of Circulating Tumor Cells (CTCs) in Blood of Patients With Advanced/Metastatic Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DEVICE: CellSearch® CTC kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of the Singapore Youth Shoulder Overuse Injury Prevention Program Among Youth Volleyball Athletes in Singapore
Status: NOT_YET_RECRUITING
Conditions: Sport Injury
Interventions: OTHER: Singapore Youth Shoulder Overuse Injury Prevention Program|OTHER: Lower body stretching program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Doxorubicin (Doxil) Combined With Rituxan, Cyclophosphamide, Vincristine and Prednisone in Newly Diagnosed Aggressive Non-Hodgkin's Lymphomas
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Doxorubicin, Rituxan, Cyclophosphamide, Vincristine and Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: JBT-101 in Systemic Lupus Erythematosus (SLE)
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus|SLE|Lupus
Interventions: DRUG: JBT-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Tissue Irrigation With Povidone Iodine in Decreasing the Rate of Surgical Site Infection Following Cesarean Section
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: DRUG: Povidone iodine 1% solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Study to Evaluate the Pharmacokinetics, Safety, Tolerability and Pharmacodynamic Effects of a Single and Multiple Oral BAY1101042 Tablet Doses in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: BAY1101042|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: SCT-I10A Plus Standard Chemotherapy in First-line Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: SCT-I10A+chemo|DRUG: Placebos+chemo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Rhinosinusitis With or Without Nasal Polyps Steroid Study
Status: WITHDRAWN
Conditions: Chronic Sinusitis|Rhinosinusitis|Nasal Polyps
Interventions: DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Evaluation of Usability and Safety of the Self-balancing Walking System Atalante in Patients With Multiple Sclerosis"
Status: COMPLETED
Conditions: Multiple Sclerosis|Ataxia|Paraplegia
Interventions: DEVICE: Atalante
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Fitusiran (ALN-AT3SC) in Severe Hemophilia A and B Patients With Inhibitors
Status: COMPLETED
Conditions: Hemophilia A|Hemophilia B
Interventions: DRUG: fitusiran|DRUG: Bypassing agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stroke Gait Rehabilitation Using Functional Electrical Stimulation
Status: COMPLETED
Conditions: Cerebrovascular Accident
Interventions: DEVICE: Fast Walking with Fast Functional Electrical Stimulation (FES) Training|OTHER: Fast Walking
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of the Dietary Supplement Taxifolin Aqua on the Recovery Period After COVID-19 Pneumonia
Status: UNKNOWN
Conditions: Covid19
Interventions: DIETARY_SUPPLEMENT: Taxifolin Aqua
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Decitabine and Gemtuzumab Ozogamicin in Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome (H-R MDS)
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Decitabine|DRUG: Gemtuzumab ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bendamustine + Pomalidomide + Dex in R/R Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Bendamustine|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Canakinumab Prefilled Syringes in Frequently Flaring Acute Gouty Arthritis Patients
Status: COMPLETED
Conditions: Acute Gouty Arthritis
Interventions: DRUG: Canakinumab pre-filled syringe|DRUG: Canakinumab lyophilized powder|DRUG: Triamcinolone Acetonide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immune Response & Safety of a Hepatitis A Vaccine Given Together With a Pneumococcal Vaccine in Healthy Children 15 m of Age
Status: COMPLETED
Conditions: Hepatitis A
Interventions: BIOLOGICAL: GSK Biologicals 2-dose inactivated hepatitis A vaccine (Havrix)|BIOLOGICAL: Prevnar™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Performance and Safety of CBL-101 Versus Vismed® Multi Eye Drops in the Management of Dry Eye
Status: COMPLETED
Conditions: Dry Eye
Interventions: DEVICE: CBL-101 Eye Drops|DEVICE: Vismed® Multi Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vexus-guided Fluid Management in Patients With Septic Shock After the Resuscitation Phase
Status: NOT_YET_RECRUITING
Conditions: Critically Ill Patients|Septic Shock
Interventions: OTHER: Fluid management according to Venous Excess Ultrasound (VExUS) Score
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Pharmacokinetics and Safety of QL1101 and EU-Avastin® in Healthy Volunteers
Status: NOT_YET_RECRUITING
Conditions: Tumor
Interventions: DRUG: QL1101|DRUG: Avastin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Inactivated Swine-Origin A/H1N1 Influenza Vaccines in Healthy European Subjects Aged 3 to 17 Years
Status: COMPLETED
Conditions: Influenza|Swine-origin A/H1N1 Influenza
Interventions: BIOLOGICAL: Swine A/H1N1 influenza vaccine (split virion, inactivated)|BIOLOGICAL: Swine A/H1N1 influenza vaccine (split virion, inactivated + Adjuvant)|BIOLOGICAL: Swine A/H1N1 influenza vaccine (split virion, inactivated + Adjuvant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Wired Magnetically Assisted Capsule Endoscopy and Esophageal Varices
Status: RECRUITING
Conditions: Esophageal Varices
Interventions: DEVICE: wired magnetic assisted capsule endoscopy|DEVICE: esophagogastroduodenoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Pembrolizumab (MK-3475) vs Standard Therapy in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Carcinoma (MK-3475-177/KEYNOTE-177)
Status: COMPLETED
Conditions: Colorectal Carcinoma
Interventions: DRUG: mFOLFOX6|DRUG: FOLFIRI|BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Bevacizumab|BIOLOGICAL: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Smart Phone Health Education on Overweight and Obese Schoolchildren's Dietary Habits and Body Composition
Status: COMPLETED
Conditions: Childhood Obesity
Interventions: OTHER: Smart Phone Education (mhealth)|OTHER: Paper Education (conventional)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Education Program to Increase Knowledge and Participation in Clinical Trials Among Racial/Ethnic and Rural Populations
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid System Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Educational Intervention|BEHAVIORAL: Health Education|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sorafenib Tosylate and Yttrium Y 90 Glass Microspheres in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Advanced Adult Hepatocellular Carcinoma|BCLC Stage C Hepatocellular Carcinoma|Recurrent Adult Hepatocellular Carcinoma|Stage III Hepatocellular Carcinoma AJCC v7|Stage IIIA Hepatocellular Carcinoma AJCC v7|Stage IIIB Hepatocellular Carcinoma AJCC v7|Stage IIIC Hepatocellular Carcinoma AJCC v7|Stage IV Hepatocellular Carcinoma AJCC v7|Stage IVA Hepatocellular Carcinoma AJCC v7|Stage IVB Hepatocellular Carcinoma AJCC v7|Unresectable Hepatocellular Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|DRUG: Sorafenib|DRUG: Sorafenib Tosylate|RADIATION: Yttrium Y 90 Glass Microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TOtal Skin Electron Beam Therapy (Low-dose) for Tumor Clone Eradication in Early-stage Mycosis Fungoides
Status: NOT_YET_RECRUITING
Conditions: Mycosis Fungoides|Cutaneous T Cell Lymphoma
Interventions: OTHER: Low-dose total-skin electron-beam therapy|OTHER: Phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Augmented Wide Area Circumferential Catheter Ablation for Reduction of Atrial Fibrillation Recurrence
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Wide area circumferential catheter ablation|PROCEDURE: Augmented- wide area circumferential ablation procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mechanically-Assisted and Non-Invasive Ventilation for Breathing-related Tumor Motion Mitigation.
Status: ACTIVE_NOT_RECRUITING
Conditions: Optimization of Motion Mitigation Strategies by Mechanically-Assisted Non-Invasive Ventilation
Interventions: DEVICE: MANIV|OTHER: Spontaneous DIBH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fast Brain MRI in Children With Suspected Brain Tumor
Status: RECRUITING
Conditions: Magnetic Resonance Imaging|Brain Neoplasms, Childhood|Brain Neoplasms|Brain Tumor|Diagnosis|Image|Neuroimaging|Pediatric
Interventions: DIAGNOSTIC_TEST: Fast MRI (Neuromix)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Integrating ePReBMs From Phoenix in Respiratory Diseases
Status: RECRUITING
Conditions: Pulmonary Hypertension|COPD|Interstitial Lung Disease|Healthy Volunteers
Interventions: DEVICE: Health Gauge AI-Based Wearable Device - Model: Phoenix
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Italian Version of the Computer-Vision Symptom Scale Questionnaire: Translation, Validation and Reliability.
Status: COMPLETED
Conditions: Video Display Terminal Workers|Computer Vision Syndrome
Interventions: DIAGNOSTIC_TEST: computer vision symptom scale (CVSS) questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Real-World Outcomes in Relapsed/Refractory Multiple Myeloma Patients Treated, or Eligible for Treatment, With Idecabtagene Vicleucel
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Idecabtagene vicleucel|OTHER: Not treated
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of SC-V Versus Conventional CPR
Status: COMPLETED
Conditions: Arrhythmia|Cardiovascular Diseases|Heart Arrest|Heart Diseases|Myocardial Infarction|Ventricular Fibrillation|Cerebral Anoxia
Interventions: PROCEDURE: cardiopulmonary resuscitation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: Recurrent Respiratory Papillomatosis and Extraesophageal Reflux
Status: COMPLETED
Conditions: Recurrent Respiratory Papillomatosis|Extra Oesophageal Reflux|Laryngeal Cyst
Interventions: PROCEDURE: Surgical collection of histology specimen|PROCEDURE: Performance of immunohistochemical analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Minocicline in Patients With Stroke
Status: UNKNOWN
Conditions: Stroke|Brain Ischemia|Paralysis
Interventions: DRUG: Minocicline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Adaptive Treatment for Early Smoking Cessation Relapse
Status: RECRUITING
Conditions: Cigarette Smoking|Smoking Behaviors|Treatment
Interventions: BEHAVIORAL: Switching to a different medication|BEHAVIORAL: Continued use of the same medication|BEHAVIORAL: Switching to a harm reduction tobacco product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer
Status: RECRUITING
Conditions: Metastatic Colorectal Adenocarcinoma|Refractory Colorectal Adenocarcinoma|Stage IV Colorectal Cancer AJCC v8
Interventions: DRUG: BET Bromodomain Inhibitor ZEN-3694|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|BIOLOGICAL: Cetuximab|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|DRUG: Encorafenib|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Multigated Acquisition Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventive Strategies in Colorectal Carcinogenesis Production and Meat Processing
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: OTHER: ham|OTHER: ham + pomegranate extract|OTHER: ham + tocopherol|OTHER: rare sirloin steak|OTHER: marinated rare sirloin steak|OTHER: marinated cooked sirloin steak
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Increasing Physical Activity in Ankylosing Spondylitis: a Randomised Controlled Trial
Status: COMPLETED
Conditions: Spondylitis, Ankylosing
Interventions: BEHAVIORAL: Brief Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of Liposomal Doxorubicin Induced Hypersensitivity Reaction in Breast Cancer Patients
Status: UNKNOWN
Conditions: Liposomal Doxorubicin Induced Hypersensitivity Reaction in Breast Cancer Patients
Interventions: OTHER: Blood sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Disclosure of Smoking in Adolescents With Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: OTHER: Group 1 - Parents will be present for the Questionnaire.|OTHER: Group 2- Parents will not be present for the Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Adding Triamcinolone Acetonide to Conbercept Treatment for Refractory Diabetic Macular Edema (CONTE)
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Macular Edema
Interventions: DRUG: Conbercept and TA|DRUG: Conbercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Pharmacokinetic Profiles and Safety of CKD-348 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CKD-348 F1, CKD-348 F2, CKD-828, D326, D337
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IRX-2, Cyclophosphamide, and Nivolumab in Treating Patients With Recurrent or Metastatic and Refractory Liver Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Hepatocellular Carcinoma|Refractory Liver Carcinoma|Stage IV Hepatocellular Carcinoma AJCC v8|Stage IVA Hepatocellular Carcinoma AJCC v8|Stage IVB Hepatocellular Carcinoma AJCC v8
Interventions: DRUG: Cyclophosphamide|BIOLOGICAL: Cytokine-based Biologic Agent IRX-2|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Monitoring of Cerebral Autoregulation After Pediatric Brain Injury
Status: RECRUITING
Conditions: Traumatic Brain Injury|Brain Injuries|Brain Injury, Vascular
Interventions: DEVICE: Transcranial Doppler
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Piromelatine in Mild Alzheimer's Disease Patients (ReCOGNITION)
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Piromelatine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Valsartan/Amlodipine Combination in Hypertensive Patients Not Controlled With Amlodipine Alone
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: valsartan/amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Primary Systemic Therapy in Operable/Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Bevacizumab|DRUG: Cyclophosphamide|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Actimetry Monitoring of the Paretic Upper Limb in Chronic Post Stroke.
Status: RECRUITING
Conditions: Chronic Stroke|Non-use of the Paretic Upper Limb
Interventions: DEVICE: Wearing bracelets (3-Axis Logging Accelerometer)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Continuous Positive Airway Pressure Device or Deep Inspiration Breath Hold in Reducing Tumor Motion in Patients Undergoing Stereotactic Body Radiation Therapy for Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Carcinoma|Malignant Respiratory Tract Neoplasm|Metastatic Malignant Neoplasm in the Lung
Interventions: DEVICE: Biphasic Positive Airway Pressure|PROCEDURE: Computed Tomography|PROCEDURE: Continuous Positive Airway Pressure|PROCEDURE: Deep Inspiration Breath Hold|RADIATION: Radiation Therapy Treatment Planning and Simulation|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Empirical Antibiotics in Acute Inflammatory Gallbladder Disease
Status: UNKNOWN
Conditions: Cholecystitis, Acute
Interventions: PROCEDURE: Laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3041658 in Adults With Hidradenitis Suppurativa
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Placebo|DRUG: LY3041658
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Alefacept in Patients With Severe Scalp Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: Alefacept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Ramucirumab Plus Pembrolizumab vs Usual Care for Treatment of Stage IV or Recurrent Non-Small Cell Lung Cancer Following Immunotherapy, Pragmatica-Lung Study
Status: RECRUITING
Conditions: Recurrent Lung Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8
Interventions: DRUG: Chemotherapy|BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Ramucirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAK-438_110 Drug Interaction With Cytochrome P450 3A4 (CYP3A4) Inhibitor Clarithromycin
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-438|DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Tanfanercept (HL036) Ophthalmic Solution in Participants With Dry Eye
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: 0.25% Tanfanercept Ophthalmic Solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Retroclavicular Approach vs Infraclavicular Approach for Brachial Plexus Block in Obese Patients
Status: UNKNOWN
Conditions: Forearm Injuries|Hand Injuries
Interventions: OTHER: Ultrasound guided retroclavicular block|OTHER: Ultrasound guided coracoid infraclavicular block|DRUG: Bupivacaine|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Ascertaining the Radiologic Prognostic Importance of Extranodal Extension on Imaging (iENE) in Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma|Extranodal Extension|Human Papilloma Virus Related Carcinoma
Interventions: OTHER: Extranodal extension
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: IonMAN II Trial- Early Feasibility Study of the IoNIR Ridaforolimus-Eluting Coronary Stent System
Status: NOT_YET_RECRUITING
Conditions: Coronary Stenosis|Coronary Artery Disease
Interventions: DEVICE: IoNIR Ridaforolimus-Eluting Coronary Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of H2 Antagonist and a Proton Pump Inhibitor of Selpercatinib in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Selpercatinib|DRUG: Ranitidine|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Paravertebral Block for Percutaneous Nephrolithotomy
Status: UNKNOWN
Conditions: Post Operative Pain
Interventions: DRUG: Group A-Paravertebral block|OTHER: Group B- No block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tailoring Bleeding Reduction Approaches in Patients Undergoing PCI
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DRUG: aspirin plus clopidogrel|DRUG: prasugrel or ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Carto Versus Ensite 3D Electroanatomical Mapping Systems for Arrhythmias Ablations
Status: WITHDRAWN
Conditions: Arrhythmias
Interventions: DEVICE: Carto|DEVICE: Ensite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Risk of Cancer in Users of Regranex (Becaplermin) and Matched Comparators (Nonusers of Regranex [Becaplermin])
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: REGRANEX (becaplermin)|OTHER: REGRANEX (becaplermin) comparators
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of an Inactivated Split-virion Influenza A(H1N1) Vaccine
Status: COMPLETED
Conditions: Influenza Infection
Interventions: BIOLOGICAL: Adjuvanted influenza A(H1N1) vaccine|BIOLOGICAL: Adjuvanted influenza A(H1N1) vaccine|BIOLOGICAL: un-adjuvanted influenza A(H1N1) vaccine|BIOLOGICAL: Adjuvanted influenza A(H1N1) vaccine|BIOLOGICAL: Adjuvanted influenza A(H1N1) vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Aripiprazole for Prevention of Relapse to Cocaine Use in Methadone-Maintenance Patients
Status: COMPLETED
Conditions: Cocaine Dependence|Cocaine-Related Disorders|Opioid-Related Disorders
Interventions: DRUG: Airipiprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of Dexlansoprazole Delayed-Release Capsules to Treat Symptomatic Nonerosive Gastroesophageal Reflux Disease in Children
Status: RECRUITING
Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: DRUG: Dexlansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT