pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Vitamin A Supplementation on Iron Metabolic Homeostasis of Preschool Children in Sichuan,China
Status: COMPLETED
Conditions: Iron Metabolic Homeostasis
Interventions: DRUG: iron and vitamin a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Human Milk Oligosaccharides (HMOs) Post-market Study on Infants
Status: COMPLETED
Conditions: Growth|Tolerance|Adverse Event|Disorder of Intestine|Disorder Lung
Interventions: OTHER: HMO-supplemented infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of a Daily Cognition Training in Older Adults Without Cognitive Impairment
Status: NOT_YET_RECRUITING
Conditions: Functional Status|Cognitive Impairment|Occupational Therapy
Interventions: OTHER: programme based on everyday cognition|OTHER: traditional cognitive stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Combination of Endometrial Injury and Freeze All Strategy in Women With a History of RIF
Status: COMPLETED
Conditions: Endometrial Injury|Hysteroscopy|Repeated Implantation Failures
Interventions: PROCEDURE: Endometrial injury
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Helicobacter Pylori Rescue Treatment Containing Tetracycline in Patients Allergic to Penicillin
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Furazolidone|DRUG: Tinidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-operative Sensitivity of a Self-adhesive Restorative Material
Status: COMPLETED
Conditions: Dental Restorations, Permanent
Interventions: PROCEDURE: Bulk-fill resin composite, (3M, ESPE)|PROCEDURE: Surefil one™ Self-Adhesive Composite Hybrid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of Healon EndoCoat Ophthalmic Viscosurgical Device (OVD)
Status: COMPLETED
Conditions: Cataracts
Interventions: DEVICE: Investigational Healon Endocoat|DEVICE: Control Healon EndoCoat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Permethrin Impregnated Underwear in Preventing Louse Proliferation in Infected Homeless
Status: TERMINATED
Conditions: Body's Louses
Interventions: DRUG: Permethrin impregnated|DRUG: no Permethrin impregnated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Safe Effective Light Dose of Photodynamic Therapy for Chronic Central Serous Chorioretinopathy
Status: UNKNOWN
Conditions: Central Serous Chorioretinopathy
Interventions: PROCEDURE: Photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Doses of Pinitol on Carbohydrate Metabolism Parameters in Healthy Subjects
Status: COMPLETED
Conditions: Healthy|Insulin Sensitivity
Interventions: DIETARY_SUPPLEMENT: Pinitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact of Memantine on Electroconvulsive Therapy (ECT): Will it Improve Response and Protect Against Cognitive Problems?
Status: WITHDRAWN
Conditions: Major Depressive Disorder
Interventions: DRUG: memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Unprotected Left Main Stenting Versus Bypass Surgery (LE MANS Study)
Status: COMPLETED
Conditions: Coronary Artery Stenosis|Myocardial Revascularization|Myocardial Ischemia
Interventions: PROCEDURE: Percutaneous Coronary Intervention|PROCEDURE: Coronary Artery Bypass Grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Stem Cell Transplant for Leukemia and Myelodysplastic Syndromes Using Clofarabine and Busulfan Regimen
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Clofarabine with Busulfan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Gabapentin in Total Knee Arthroplasty (TKA)
Status: COMPLETED
Conditions: Postoperative Pain|Postoperative Sedation
Interventions: DRUG: Gabapentin|DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TBTC Study 27/28 PK: Moxifloxacin Pharmacokinetics During TB Treatment
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: Moxifloxacin|DRUG: Isoniazid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: hCAP18 Levels and Vitamin D Deficiency in Chronic Kidney Disease
Status: WITHDRAWN
Conditions: Chronic Kidney Disease|Vitamin D Deficiency
Interventions: DRUG: Ergocalciferol|DRUG: Calcitriol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vorinostat Combined With Gemtuzumab Ozogamicin, Idarubicin and Cytarabine in Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Salvage reinduction chemotherapy including Gemtuzumab ozogamicin, Idarubicin and Cytarabine and Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hybrid Type 1 Randomized Pilot Trial of a Peer-led Family and Social Strengthening Group Intervention for Refugee Families
Status: RECRUITING
Conditions: Depression|Anxiety|PTSD|Family Dynamics|Social Functioning|Family Support|Family Relations
Interventions: BEHAVIORAL: CAFES2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Exemestane With and Without Entinostat (SNDX-275) in Treatment of Postmenopausal Women With Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Estrogen Receptor-Positive Breast Cancer|Breast Cancer, Estrogen Receptor-Positive|ER+ Breast Cancer
Interventions: DRUG: entinostat|DRUG: exemestane|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Functional Parenchymal Volume and Split Renal Function Before and After Partial Nephrectomy
Status: UNKNOWN
Conditions: Renal Cell Carcinoma
Interventions: PROCEDURE: On-clamp partial nephrectomy|PROCEDURE: Off-clamp partial nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Intracoronary Ad5FGF-4 in Patients With Stable Angina
Status: UNKNOWN
Conditions: Stable Angina
Interventions: GENETIC: AdF5FGF-4 vs. Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pyridostigmine in Severe SARS-CoV-2 Infection
Status: UNKNOWN
Conditions: COVID-19|SARS-CoV-2
Interventions: DRUG: Pyridostigmine Bromide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NWT03 and Arterial Stiffness
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: NWT-03, an egg-white protein hydrolysate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The U.K. Embryologist Fatigue Study
Status: COMPLETED
Conditions: Fatigue|Stress|Burnout, Professional|Musculoskeletal Pain|Back Pain|Neck Pain|Headache|Dizziness|Sleep Disturbance|Chest Pain|Syncope|Cardiovascular Diseases|Shortness of Breath|Gastrointestinal Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analgesic Duration of Long Acting Local Anesthetics for Low Volume Ultrasound-guided Interscalene Brachial Plexus Block
Status: COMPLETED
Conditions: Brachial Plexus Block|Anesthetics, Local
Interventions: DRUG: Ropivacaine 0.5%|DRUG: Ropivacaine 1%|DRUG: Bupivacaine 0.5% + epinephrine 1:200,000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Computer-Based Simulation of DKA Management
Status: COMPLETED
Conditions: Diabetes
Interventions: OTHER: Coach, Preselected number of cases|OTHER: Coach, Self-selected number of cases|OTHER: No coach, Preselected number of cases|OTHER: No coach, Self-selected number of cases
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose:
Clinical trial: Osteopathic Manipulative Medicine to Reduce Developmental Delays
Status: COMPLETED
Conditions: Extreme Prematurity|Neurodevelopmental Abnormality
Interventions: OTHER: Osteopathic Manipulative Medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of DA-9805 for Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: DA-9805 45mg|DRUG: DA-9805 90mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 5-Week Trial Of PD 0332334 And Alprazolam Extended Release Compared To Placebo In Patients With Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: PD 0332334|DRUG: PD 0332334|DRUG: placebo|DRUG: Alprazolam extended release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Emergency Preparedness for Caregivers of Persons With Dementia: Disaster PrepWise
Status: RECRUITING
Conditions: Caregiver Resilience and Stress
Interventions: BEHAVIORAL: Disaster PrepWise-Caregiver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy Study of Pharmacist Intervention on Medication-related Problems in Hemodialysis Patients
Status: UNKNOWN
Conditions: Renal Failure Chronic Requiring Hemodialysis
Interventions: BEHAVIORAL: pharmaceutical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Study of GKT in Diabetes Related Dementia
Status: NOT_YET_RECRUITING
Conditions: Dementia
Interventions: DRUG: Ginkgo Ketone Ester Tablets|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Vitamin D Vitamers on Vitamin D Status
Status: COMPLETED
Conditions: Vitamin D Status
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Vitamin D2|DIETARY_SUPPLEMENT: 25OHD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: B-cell Malignancy|Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma|Waldenstrom Macroglobulinemia|Mantle Cell Lymphoma|Marginal Zone Lymphoma|Follicular Lymphoma|Non-Hodgkin Lymphoma
Interventions: DRUG: AS-1763
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome
Status: RECRUITING
Conditions: Uveal Melanoma|Cutaneous Melanoma|BAP1 Gene Mutation|Renal Cell Carcinoma|Mesothelioma|Hepatocellular Carcinoma|Cholangiocarcinoma|Meningioma Atypical
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The iPeer2Peer Program for Adolescents With Juvenile Idiopathic Arthritis
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: BEHAVIORAL: iPeer2Peer Mentorship|OTHER: Active Comparator: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Role of Mucin and Mucin Glycosylating Enzymes in Nasopharyngeal Carcinoma and Salivary Gland Cancer and Their Correlation With Clinical Prognosis
Status: UNKNOWN
Conditions: Salivary Gland Cancer|Nasopharyngeal Carcinoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of tDCS in M1 and DLPFC on Pain Processing in Healthy Volunteers
Status: COMPLETED
Conditions: Pain Processing in Healthy Volunteers
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Pharmacokinetic/Pharmacodynamic Profile of Orally Administered Leuprolide in Healthy Female Volunteers
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Leuprolide Oral Tablet 4-mg QD|DRUG: Leuprolide Oral Tablet 4-mg BID|DRUG: Leuprolide Depot|DRUG: Leuprolide Oral Tablet 10-mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Safety of NKT Cell Infusion in Patients With Advanced Solid Tumor
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|Gastric Cancer|Hepatocellular Carcinoma|Colorectal Cancer
Interventions: BIOLOGICAL: natural killer T cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Escitalopram on the Pharmacokinetics and Pharmacodynamics of Tramadol in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: escitalopram and tramadol|DRUG: placebo|DRUG: placebo and tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stroke Volume Variation and Plethysmography Variability Index as Goal Directed Fluid Therapy in Major Oncosurgeries
Status: COMPLETED
Conditions: Goal Directed Fluid Therapy
Interventions: OTHER: Intraoperative SVV Guided Fluid Therapy|OTHER: Intraoperative PVI Guided Fluid Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study to Demonstrate the Lot-to-lot Consistency and to Evaluate the Safety of an Adjuvanted Influenza Vaccine Candidate
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Candidate Influenza Vaccine GSK1247446A - 3 different formulations|BIOLOGICAL: Fluarix TM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Alcohol Health Education With Personalized Feedback Boosters
Status: COMPLETED
Conditions: College Student Drinking
Interventions: BEHAVIORAL: e-checkup to go|BEHAVIORAL: Norms-only booster|BEHAVIORAL: Norms-plus-Strategies booster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pegaptanib Sodium on Foveal Thickening in Patients With Exudative Subfoveal Age-Related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: Macugen ™ (pegaptanib sodium injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6)
Status: COMPLETED
Conditions: Tuberous Sclerosis Complex|Seizures
Interventions: DRUG: GWP42003-P|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of BI 1356 After Single Oral Administration Given as Different Tablet Formulation in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1356 - Tablet TFII|DRUG: BI 1356 - Tablet iFF|DRUG: BI 1356 - Tablet TFIIb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Neoadjuvant Atezolizumab Plus Chemotherapy Versus Placebo Plus Chemotherapy in Patients With Resectable Stage II, IIIA, or Select IIIB Non-Small Cell Lung Cancer (IMpower030)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small-Cell Lung
Interventions: DRUG: Atezolizumab (MPDL3280A), an engineered anti-PD-L1 antibody|DRUG: Placebo Comparator|DRUG: Nab-paclitaxel|DRUG: Pemetrexed|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Morphine IV vs Paracetamol IV in Neonates and Infants After Cardiac Surgery
Status: COMPLETED
Conditions: Analgesia|Congenital Heart Disease|Surgery
Interventions: DRUG: paracetamol|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Effectiveness, Safety, and Tolerability of Two Different Hepatitis C Treatments in Patients Infected With Both HIV and Hepatitis C Virus (HCV)
Status: COMPLETED
Conditions: HIV Infections|Hepatitis C
Interventions: DRUG: Ribavirin|DRUG: Interferon alfa-2a|DRUG: Peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine (HCQ) for Recurrent Pregnancy Loss
Status: UNKNOWN
Conditions: Recurrent Pregnancy Loss
Interventions: DRUG: Hydroxychloroquine|DRUG: Hydroxychloroquine placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cinnamon on Patients With Chronic Prostatitis/Chronic Pelvic Pain Syndrome; a Pilot Study
Status: COMPLETED
Conditions: Chronic Prostatitis|Chronic Pelvic Pain Syndrome
Interventions: DIETARY_SUPPLEMENT: cinnamon capsules|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-coated Aspirin in Patients With StablE Diabetes II
Status: RECRUITING
Conditions: Platelet Aggregation|Type 2 Diabetes|Aspirin|Diabetes Mellitus, Type 2|Platelet Aggregation Inhibitors
Interventions: DRUG: Aspirin 81Mg Ec Tab twice daily for 7 days|DRUG: Aspirin 40Mg Chew Tab twice daily for 7 days|DRUG: Aspirin 162 mg EC Tab once daily for 7 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dietary Impacts on Glucose-lowering Effects of Sitagliptin in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Sitagliptin|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of HS-10241 Combined With Almonertinib Versus Platinum-based Chemotherapy in Treatment of Advanced NSCLC With MET Amplification After Failure of EGFR-TKI Therapy
Status: NOT_YET_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: HS-10241+ Almonertinib|DRUG: Pemetrexed + Cisplatin /Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Oral Levosimendan on Ambulatory Electrocardiographic Variables
Status: COMPLETED
Conditions: Transient Ischemic Attack|Stroke
Interventions: DRUG: Levosimendan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Manual Acupuncture and Standard Therapy Compared to Standard Therapy in Gynecological Cancer Pain
Status: COMPLETED
Conditions: Gynecologic Cancer|Cancer Related Pain|Cancer Pain|Acupuncture
Interventions: OTHER: Manual Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: This is a Two-year Follow-up Study to Evaluate the Long-term Safety, Tolerability and Efficacy of 2 Different Doses of Everolimus
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: DRUG: Everolimus (RAD001)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Triamcinolone for Ahmed Glaucoma Valve
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Adjunctival Triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Efficacy and Safety of MUCOLASE Tablet(Streptokinase • Streptodornase)
Status: UNKNOWN
Conditions: Acute Upper Respiratory Infection|Acute Bronchitis
Interventions: DRUG: MUCOLASE tablet (streptokinase • streptodornase)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EGFRvIII CAR T Cells for Newly-Diagnosed WHO Grade IV Malignant Glioma
Status: TERMINATED
Conditions: Glioblastoma|Gliosarcoma
Interventions: BIOLOGICAL: EGFRvIII CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence and Characteristics of Transthyretin Amyloidosis in Patients With Left Ventricular Hypertrophy of Unknown Etiology
Status: COMPLETED
Conditions: Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)
Interventions: DIAGNOSTIC_TEST: Diagnosis of TTR amyloidosis cardiomyopathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TactiSense IDE Trial of TactiCath SE for Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: TactiCath SE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Medical Treatment of Difficult-to-treat Hypertension
Status: RECRUITING
Conditions: Hypertension
Interventions: DRUG: Phase C: Eplerenone|DRUG: Phase C: Spironolactone|DRUG: Phase C: Torasemide|DRUG: Phase B: Triplixam / Elestar HCT|DIAGNOSTIC_TEST: Phase A: Confirmation of uncontrolled hypertension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glutamine and Insulin Sensitivity in Type I Diabetes
Status: COMPLETED
Conditions: Type I Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Glutamine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrent vs. Sequential Sipuleucel-T & Abiraterone Treatment in Men With Metastatic Castrate Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer Metastatic|Hormone Refractory Prostate Cancer|Castration-resistant Prostate Cancer
Interventions: BIOLOGICAL: sipuleucel-T|DRUG: abiraterone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intravitreal Ranibizumab Combined With Panretinal Photocoagulation in Patients With Proliferative Diabetic Retinopathy
Status: COMPLETED
Conditions: Diabetic Retinopathy|Retinal Diseases|Eye Diseases|Diabetic Angiopathies|Vascular Diseases|Cardiovascular Diseases
Interventions: DRUG: Ranibizumab|PROCEDURE: Laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immediate Effects of Bowen Technique Versus Dynamic Soft Tissue Mobilization on Hamstrings Tightness in Chronic Non-specific Low Back Pain.
Status: RECRUITING
Conditions: Hamstring Tightness
Interventions: PROCEDURE: Conventional therapy for hamstring tightness|PROCEDURE: Bowen Technique|PROCEDURE: Dynamic Soft Tissue Mobilization (DSTM):
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Satir Model for Self-esteem, Mental Health, and Family Function Among Individuals With Substance Use Disorders
Status: COMPLETED
Conditions: Drug Abuse|Self Esteem|Mental Health Wellness 1|Family Dysfunction
Interventions: OTHER: Satir group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Dexmedetomidine on Prevention of Postoperative Acute Kidney Injury in Patients Undergoing Aortic Surgery
Status: COMPLETED
Conditions: Acute Kidney Injury(Postoperative Acute Kidney Injury in Patients Undergoing Aortic Surgery)
Interventions: DRUG: dexmedetomidine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fluid Responsiveness in the Postoperative Patient: a Prospective Study
Status: UNKNOWN
Conditions: Actual Impaired Fluid Volume
Interventions: DRUG: Fluid challenge (250 ml Lactated Ringer's solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Investigating Public Enthusiasm for Mammography Screening in Denmark
Status: COMPLETED
Conditions: Breast Neoplasm Female|Mammography Screening|Decision Making|Information Seeking Behavior
Interventions: BEHAVIORAL: Information about hypothetical mammography screening without benefits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Monoclonal Antibody Therapy, Cyclosporine, and Paclitaxel in Treating Patients With Recurrent or Refractory Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: monoclonal antibody m170|DRUG: cyclosporine|DRUG: paclitaxel|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: yttrium Y 90 monoclonal antibody m170
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of a Drug Education and Diversion Program for Middle and High School Students
Status: ENROLLING_BY_INVITATION
Conditions: Adolescent Behavior|Substance Use|Youth|Health Risk Behaviors
Interventions: BEHAVIORAL: iDECIDE (Drug Education Curriculum: Intervention, Diversion, and Empowerment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Novel Approach to Reducing Adiposity Among Young Men
Status: COMPLETED
Conditions: Weight Loss|Men|Lifestyle Risk Reduction|Cardiovascular Diseases|Obesity
Interventions: BEHAVIORAL: Self-guided lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Evaluation of Using the Entire Papilla Preservation Technique With and Without Autogenous Bone Graft and Injectable Platelet Rich Fibrin in Treatment of Periodontal Intraosseous Defects
Status: RECRUITING
Conditions: Isolated Intrabony Periodontal Defects in Patients With Periodontitis
Interventions: OTHER: Entire papilla preservation technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Shear Wave Elastography of Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DEVICE: Transrectal shear wave elastography of the prostate|PROCEDURE: Transrectal random biopsy of the prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multiple Sclerosis, Menstrual Cycle and Physical Acivity
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: Strength training sessions and High-interval intensity training sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Study Between Hyperbaric Therapy and Intravesical Dimethyl Sulfoxide Instillation for Interstitial Cystitis
Status: UNKNOWN
Conditions: Interstitial Cystitis
Interventions: OTHER: Hyperbaric Oxygen Therapy|DRUG: DMSO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Titer O Positive Whole Blood Versus Component Therapy for Emergent Transfusion in Trauma Patients
Status: COMPLETED
Conditions: Hemorrhagic Shock|Acute Blood Loss Anemia|Traumatic Brain Injury
Interventions: COMBINATION_PRODUCT: Routine labs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Identifying Strategies to Curtail Weight Regain After GLP-1 Receptor Agonist Treatment Cessation
Status: RECRUITING
Conditions: Obesity
Interventions: OTHER: Medically tailored meals|BEHAVIORAL: Noom®|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intranasal INNA-051 for Prevention of COVID-19 in Adults
Status: WITHDRAWN
Conditions: COVID-19 Pandemic
Interventions: DRUG: INNA-051|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: QT Changes in Geriatric Patients: a Comparison of Spinal and General Anesthesia
Status: COMPLETED
Conditions: Anesthesia, Spinal|Sevoflurane|Long QT Syndrome
Interventions: DIAGNOSTIC_TEST: QT and QTc interval
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Motor Learning in Individuals With Lower Limb Loss and Chronic Diabetes
Status: UNKNOWN
Conditions: Amputation|Diabetes Mellitus|Neuropathy, Diabetic
Interventions: BEHAVIORAL: Instructions to perform a motor task (external vs. internal focus instructions)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of TAK-438 for the Prevention of Recurrent Gastric or Duodenal Ulcers During Therapy of Low-dose Aspirin
Status: COMPLETED
Conditions: Gastric Ulcers|Duodenal Ulcers
Interventions: DRUG: TAK-438|DRUG: Placebo|DRUG: TAK-438|DRUG: Placebo|DRUG: Lansoprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Efficacy of Ivabradine Versus Metoprolol
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Ivabradine and Metoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Canagliflozin and Myocardial Micro-perfusion
Status: RECRUITING
Conditions: Type 2 Diabetes|Cardiovascular Diseases|Cardiac Perfusion Defect
Interventions: DRUG: Canagliflozin 100mg or Sitagliptin 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Supraclavicular Lymph Node Dissection for Ipsilateral Supraclavicular Lymph Node Metastatic Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Ipsilateral Supraclavicular Lymph Node Metastasis
Interventions: PROCEDURE: Supraclavicular lymph node dissection combined with radiotherapy|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relovair PD PK in Chinese Healthy Subjects
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone Furoate/Vilanterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Spironolactone With Patiromer in the Treatment of Resistant Hypertension in Chronic Kidney Disease
Status: COMPLETED
Conditions: Hyperkalemia|Resistant Hypertension
Interventions: DRUG: Patiromer|DRUG: Placebo|DRUG: Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Depth of Hypnosis and Postoperative Nausea and Vomiting During Xenon Anaesthesia
Status: COMPLETED
Conditions: Anaesthetics Gases, Xenon|Anaesthetics Volatile, Sevoflurane|Depth of Anaesthesia|Postoperative Nausea|Postoperative Vomiting
Interventions: DRUG: Xenon|DRUG: Sevoflurane|DRUG: Dexamethasone|DRUG: NaCl|DRUG: Ondansetron|DRUG: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Two Manufacturing Processes for Levonorgestrel 90 mg/Ethinyl Estradiol 20 mg (LNG/EE) in Healthy, Cycling Women
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: levonorgestrel/ethinyl estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Tolerability of Iberdomide (CC-220) in Combination With Polatuzumab Vedotin Plus Rituximab or Tafasitamab or Rituximab Plus Chemotherapy in B-cell Lymphoma
Status: WITHDRAWN
Conditions: Lymphoma, B-Cell
Interventions: DRUG: CC-220|DRUG: Polatuzumab vedotin|DRUG: Rituximab|DRUG: Tafasitamab|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Dexamethasone|DRUG: Bendamustine|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation as Therapy for Depression in Amyotrophic Lateral Sclerosis
Status: WITHDRAWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DEVICE: active repetitive transcranial magnetic stimulation|DEVICE: sham repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Walking Exercise in Improving Cognitive Function in Older Adults With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Stretching exercise|BEHAVIORAL: Low-frequency, moderate-intensity walking group|BEHAVIORAL: High-frequency, moderate-intensity walking group|BEHAVIORAL: Low-frequency, vigorous-intensity walking group|BEHAVIORAL: High-frequency, vigorous-intensity walking group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LFR-260 vs Traditional Phoropter in Visual Acuity Testing
Status: COMPLETED
Conditions: Visual Acuity|Astigmatism|Anisometropia
Interventions: DEVICE: LFR-260 portable phoropter|DEVICE: Traditional phoropter (Standard of Care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Exercise is Medicine for Patients With CKD
Status: COMPLETED
Conditions: Chronic Kidney Disease stage4|Chronic Kidney Disease Stage V|Physical Activity
Interventions: BEHAVIORAL: EIM Fitness Practitioners|BEHAVIORAL: Counseling and wearable device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: CIrculating Tumour DNA in Lung Cancer (CITaDeL): Optimizing Sensitivity and Clinical Utility
Status: COMPLETED
Conditions: Lung Neoplasms|Lung Cancer|Neoplasm of Lung|Non Small Cell Lung Cancer
Interventions: OTHER: Circulating tumour DNA (ctDNA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Open Label Comparative Trial of Dinoprostone Plus or Minus Oxytocin Versus Oxytocin Alone in Cervical Ripening for Labor Induction
Status: TERMINATED
Conditions: Vaginal Delivery|Cesarean Section
Interventions: DRUG: Dinoprostone|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GLP-1: Acute Effects on Kidney Function in Healthy Men
Status: COMPLETED
Conditions: Kidney Functional
Interventions: BIOLOGICAL: Human GLP-1 (7-36) amide|BIOLOGICAL: Isotone NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Epigallocatechingallate (EGCG) in Cardiac AL Amyloidosis
Status: TERMINATED
Conditions: Primary Amyloidosis of Light Chain Type
Interventions: DRUG: Diuretics (plus antiarrhythmic drugs, i.e. amiodarone, in case of complex ventricular arrhithmias)|DRUG: Diuretics (plus antiarrhythmic drugs, i.e. amiodarone, in case of complex ventricular arrhythmias) plus EGCG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess The Performance And Tolerance Of Janesse 20 In The Volume Restoration Of Labia Majora
Status: UNKNOWN
Conditions: Dysmorphic Disorder (BDD)|Congenital Labia Majora Hypotrophy|Post-menopausal Labia Majora Hypotrophy
Interventions: DEVICE: Janesse 20 (Cross-linked Hyaluronic Acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Removable Versus Fixed Implant-supported Prostheses in Oral Health Quality of Life for Edentulous Patients
Status: NOT_YET_RECRUITING
Conditions: Complete Edentulism
Interventions: OTHER: fixed implant denture|OTHER: removable implant denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Rituximab and Bendamustine With or Without Brentuximab Vedotin for CD30 Positive Diffuse Large B-cell Lymphoma
Status: TERMINATED
Conditions: Diffuse Large B-cell Lymphoma Refractory|Follicular B-cell Non-Hodgkin's Lymphoma
Interventions: DRUG: Brentuximab Vedotin|DRUG: Rituximab|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Inspiratory Muscle Training in Patients With Non-Specific Chronic Neck Pain
Status: UNKNOWN
Conditions: Neck Pain
Interventions: OTHER: Conventional plus Functional Inspiratory Muscle Training Group|OTHER: Conventional Physiotherapy Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Observational Study to Evaluate Safety, Efficacy and Convenience of Using NovoMix® 30 FlexPen® in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2|Delivery Systems
Interventions: DRUG: biphasic insulin aspart 30
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antibiotics During Intrauterine Balloon Tamponade Placement
Status: TERMINATED
Conditions: Obstetric Complication|Postpartum Hemorrhage|Postpartum Endometritis
Interventions: DRUG: CeFAZolin 1000 MG|DRUG: Clindamycin 900 MG in 6 ML Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: M7824 in Patients With Metastatic Colorectal Cancer or With Advanced Solid Tumors With Microsatellite Instability
Status: ACTIVE_NOT_RECRUITING
Conditions: Colon Adenocarcinoma|High-Frequency Microsatellite Instability|Metastatic Malignant Solid Neoplasm|Rectal Adenocarcinoma|Refractory Colorectal Carcinoma|Stage IV Colon Cancer AJCC v8|Stage IV Rectal Cancer AJCC v8|Stage IVA Colon Cancer AJCC v8|Stage IVA Rectal Cancer AJCC v8|Stage IVB Colon Cancer AJCC v8|Stage IVB Rectal Cancer AJCC v8
Interventions: BIOLOGICAL: Anti-PD-L1/TGFbetaRII Fusion Protein M7824
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photographic Email Correspondence for Pediatric Urology Post-Operative Patients
Status: COMPLETED
Conditions: Post-Operative Complication|Pediatric Urology
Interventions: OTHER: Digital Photograph|OTHER: Telephone Call
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Osimertinib With Stereotactic Radiosurgery (SRS) in Brain Metastases From EGFR Positive NSCLC
Status: COMPLETED
Conditions: NSCLC|Non-small Cell Lung Cancer
Interventions: DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fespixon Cream for the Treatment of Chronic Diabetic Foot Ulcers (TEXAS 1A, 2A) in Dialysis Patients
Status: COMPLETED
Conditions: Chronic Diabetic Foot Ulcer
Interventions: DRUG: Fespixon Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Randomized Clinical Trial Comparing Chi-BEAM With BEAM Regimen Combined With ASCT for the Treatment of ND PTCL
Status: RECRUITING
Conditions: Newly Diagnosed Peripheral T-cell Lymphoma
Interventions: DRUG: C-BEAM Regimen|DRUG: BEAM Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement and Treatment of Back Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Back Pain
Interventions: DEVICE: Negative pressure and Laser|DEVICE: Positive Pressure and Laser|DEVICE: Ultrasound and Laser|DEVICE: Laser|DEVICE: Placebo Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of Intramuscular Inactivated Poliovirus Vaccine
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: bOPV/IPV (6 weeks)|BIOLOGICAL: bOPV/IPV (14 weeks)|BIOLOGICAL: bOPV/IPV (6 & 14 weeks)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Lapaquistat Acetate on Blood Cholesterol Levels in Subjects With Elevated Cholesterol
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: Lapaquistat Acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Forteo for the Treatment of Unexplained Osteoporosis in Premenopausal Women
Status: COMPLETED
Conditions: Menopause|Fracture|Osteoporosis
Interventions: DRUG: Teriparatide (PTH 1-34)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT