pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: VIveve Treatment of the Vaginal Introitus to EValuate Effectiveness
Status: COMPLETED
Conditions: Vaginal Laxity Following Childbirth|Sexual Function Following Childbirth
Interventions: DEVICE: Active Treatment Viveve|DEVICE: Sham Treatment Viveve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the ELAD System (ELAD) to Treat Acute Liver Failure (ALF)
Status: TERMINATED
Conditions: Acute Liver Failure|Fulminant Hepatic Failure|Primary Graft Non-Function|Surgically-Induced Liver Failure
Interventions: BIOLOGICAL: ELAD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of SenseGuard™ to Detect Respiratory Changes, During Home Monitoring of Subjects With High Risk of AECOPD.
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DEVICE: SenseGuard Investigational Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparing the Effects of Levobupivacaine and Bupivacaine in Saddle Spinal Anesthesia
Status: COMPLETED
Conditions: Outpatients|General Surgery|Anorectal Disorder|Anesthesia|Drug Effect
Interventions: DRUG: Levobupivacaine (as Levobupivacaine Hydrochloride) 75 Mg/10 mL Solution for Injection Ampoule|DRUG: Bupivacaine/Dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Abscopal Effect From Low-dose Radiotherapy in Metastatic Cancer Combined With Stereotactic Body Radiotherapy
Status: NOT_YET_RECRUITING
Conditions: Neoplasms|Secondary Malignant Neoplasm
Interventions: RADIATION: SBRT + LDRT|RADIATION: SBRT alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Zinc Sulfate With Probiotics for the Treatment of Acute Diarrhea in Children
Status: UNKNOWN
Conditions: Acute Watery Diarrhoea
Interventions: DRUG: Zinc Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 3DV+TPS Software Outlines the Radiotherapy of Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Radiotherapy|Nasopharyngeal Carcinoma
Interventions: DEVICE: 3DV+TPS；VARIAN TPS；FonicsPlan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison Between Split Septum and Mechanical Valve Needleless Connector in Preterm Babies
Status: NOT_YET_RECRUITING
Conditions: Sepsis, Neonatal
Interventions: DEVICE: Split septum needleless connector|DEVICE: Mechanical valve needleless connector
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomised Comparison on the Dose Requirement Between, Levobupivacaine, Ropivacaine and Bupivacaine in Intrathecal Anaesthesia
Status: COMPLETED
Conditions: Anesthesia, Conduction|Surgery
Interventions: PROCEDURE: Combined spinal epidural anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Trial Scheme of Ganoderma Lucidum Spore Powder for Postoperative Chemotherapy of Osteosarcoma
Status: NOT_YET_RECRUITING
Conditions: Osteosarcoma
Interventions: DRUG: Ganoderma lucidum|DRUG: Chemotherapy|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Head Impact Exposure in Hawaii High School Football
Status: COMPLETED
Conditions: Head Trauma|Cognitive Change|Confidence, Self|Sports Injuries in Children
Interventions: BEHAVIORAL: HuTT-2x|BEHAVIORAL: HuTT-4x
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise
Status: NOT_YET_RECRUITING
Conditions: Chronic Lung Disease|Chronic Obstructive Pulmonary Disease|Acute Lymphoblastic Leukemia|Heart Transplant
Interventions: OTHER: Physical activity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of KRP203 in Subacute Cutaneous Lupus Erythematosus
Status: COMPLETED
Conditions: Subacute Cutaneous Lupus Erythematosus
Interventions: DRUG: KRP203 - 1.2mg|DRUG: Placebo to KRP203 - 1.2 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Vasopressor Medication to Support Blood Pressure During Intubation Procedure
Status: COMPLETED
Conditions: Respiratory Failure|Hypotension and Shock|Hypotension on Induction|Intubation Complication|Anesthesia Intubation Complication
Interventions: DRUG: Norepinephrine|DRUG: Lactated Ringers, Intravenous|DRUG: normal saline|DRUG: Plasma-lyte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ActaVisc and ActaVisc Mx Intra-articular Injection for Pain Associated With Osteoarthritis in the Knee
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: OTHER: ActaVisc and ActaVisc Mx Intra-articular Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MK-8189 in Participants With Bipolar I Disorder (MK-8189-020)
Status: ACTIVE_NOT_RECRUITING
Conditions: Bipolar I Disorder
Interventions: DRUG: MK-8189|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GERD Following Laparoscopic Sleeve Gastrectomy
Status: WITHDRAWN
Conditions: Morbid Obesity
Interventions: PROCEDURE: 3 cm start of resection|PROCEDURE: 6 cm start of resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Improving Help-seeking for Depression Care in Nepal
Status: ACTIVE_NOT_RECRUITING
Conditions: Help-Seeking Behavior|Depression
Interventions: BEHAVIORAL: Gain-Life (Give informAtIoN to transform Life)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy Multicentre Trial of ImmunoTherapy Vaccination With Abagovomab to Treat Ovarian Cancer Patients
Status: TERMINATED
Conditions: Ovarian Cancer
Interventions: BIOLOGICAL: Abagovomab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gabapentin For the Control of Hot Flashes in Women With Breast Cancer
Status: COMPLETED
Conditions: Anxiety Disorder|Breast Cancer|Depression|Hot Flashes
Interventions: DRUG: gabapentin|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Electrical Pudendal Nerve Stimulation and Sacral in Treating Non-obstructive Neurogenic Urinary Retention
Status: RECRUITING
Conditions: Urinary Retention
Interventions: PROCEDURE: electrical pudendal nerve stimulation|PROCEDURE: sacral neuromodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Immunogenicity of GR2001 in Chinese Healthy Adults
Status: COMPLETED
Conditions: Tetanus
Interventions: BIOLOGICAL: GR2001|BIOLOGICAL: Placebo|BIOLOGICAL: HTIG|BIOLOGICAL: Tetanus Toxoid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Confirmation Study of Combivent HFA Inhalation Aerosol in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Placebo Combivent HFA|DRUG: Combivent HFA|DRUG: Combivent (CFC)|DRUG: Placebo Combivent (CFC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing High-flow Nasal Oxygen With Standard Management for Conscious Sedation During Endoscopic Retrograde Cholangiopancreatography in Prone Position
Status: COMPLETED
Conditions: Patients Undergoing Endoscopic Retrograde Cholangiopancreatography in Prone Position
Interventions: BIOLOGICAL: high-flow humidified oxygen-delivery system (OptiFlow THRIVE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Change in Serum Chloride Level After Loading Dose of Sterofundin Solution Compared With Normal Saline Solution
Status: COMPLETED
Conditions: Change in Serum Chloride Level
Interventions: DRUG: Sterofundin|DRUG: NSS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVO
Status: TERMINATED
Conditions: Macular Edema|Retinal Vein Occlusion
Interventions: DRUG: suprachoroidal CLS-TA|DRUG: suprachoroidal sham|DRUG: IVT aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of NAFLD and Advanced Fibrosis in Patients With Type 1 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Nonalcoholic Fatty Liver|Nonalcoholic Steatohepatitis|Fibrosis, Liver|Type 1 Diabetes|Cirrhosis, Liver
Interventions: DEVICE: Transient Elastography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Dual Therapy as First-line Treatment for Hp Infection
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Vonoprazan|DRUG: Rabeprazole|DRUG: Amoxicillin|DRUG: Clarithromycin|DRUG: Colloidal bismuth pectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy and Safety of Fluticasone Furoate/Vilanterol Inhalation Powder (FF/VI) Compared With Vilanterol Inhalation Powder (VI) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Fluticasone Furoate/Vilanterol|DRUG: Vilanterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Plasma Exchange Therapy for Post- COVID-19 Condition: A Pilot, Randomized Double-Blind Study
Status: COMPLETED
Conditions: Post-COVID19 Condition
Interventions: COMBINATION_PRODUCT: Plasma Exchange Procedure|OTHER: Sham Plasma Exchange Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Long Term Extension Study Evaluating Safety Of Sildenafil Citrate When Used To Treat Pulmonary Arterial Hypertension (PAH) In Children
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Sildenafil citrate|DRUG: Sildenafil citrate|DRUG: Sildenafil citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of Anakinra in the Treatment of Acute Gouty Arthritis
Status: COMPLETED
Conditions: Acute Gouty Arthritis
Interventions: DRUG: Anakinra 100 mg|DRUG: Triamcinolone Acetonide 40 mg|DRUG: Placebo to Anakinra 100 mg|DRUG: Placebo to Triamcinolone Acetonide 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hepatic Artery Infusion Pump for NPC Liver Metastases
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma|Neoplasm Metastasis|Liver
Interventions: PROCEDURE: DSA-guided implantation of hepatic artery infusion pump|DRUG: Gemcitabine|DRUG: Floxuridine|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bridging Active Heroin Users to Hepatitis C Treatment Using Buprenorphine - 1
Status: COMPLETED
Conditions: Hepatitis C|Heroin Dependence
Interventions: DRUG: Buprenorphine/naloxone|DRUG: pegInterferon
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibacterial Treatment Against Diarrhea in Oral Rehydration Solution
Status: TERMINATED
Conditions: Diarrhea
Interventions: OTHER: T4 phage cocktail test|OTHER: Commercial T4 phage cocktail|OTHER: standard oral rehydration solution (ORS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-inferiority Comparison of Efficacy and Safety of Penciclovir 10mg/g to Acyclovir 50mg/g in the Treatment of Recurrent Herpes Labialis
Status: COMPLETED
Conditions: Herpes Labialis
Interventions: DRUG: Acyclovir 50mg/g|DRUG: Penciclovir 10mg/g
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PRevention of Macular EDema After Cataract Surgery
Status: COMPLETED
Conditions: Cystoid Macular Edema|Cataract|Diabetes Mellitus
Interventions: DRUG: Bromfenac|DRUG: Dexamethasone|DRUG: Bevacizumab|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Fixed-dose Combination of Etoricoxib + Cyclobenzaprine for Pain Relief After Third Molar Extraction in Brazil
Status: WITHDRAWN
Conditions: Third Molar Extraction
Interventions: DRUG: FDC of etoricoxib + cyclobenzaprine + etoricoxib placebo|DRUG: etoricoxib 90 mg (Arcoxia®) +FDC placebo|DRUG: cyclobenzaprine hydrochloride + etoricoxib placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: One Hospital ClinicalService Project
Status: WITHDRAWN
Conditions: Arrhythmias, Cardiac|Bradycardia|Syncope
Interventions: DEVICE: Implantable Cardioverter-Defibrillator (ICD)|DEVICE: Implantable Pacemaker Generator (IPG)|DEVICE: Implantable Loop Recorder (ILR)|DEVICE: Cardiac Resynchronization Therapy-Defibrillator (CRT-D)|DEVICE: Implantable devices working as neurostimulators, stents, spinal/bone devices or other applications
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Two Bronchodilator Inhalers in Adolescents and Adults With Exercise-Induced Asthma
Status: COMPLETED
Conditions: Exercise-induced Bronchospasm
Interventions: DRUG: albuterol aerosol by HFA MDI|DRUG: albuterol aerosol by HFA BOI|DRUG: placebo aerosol by HFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Carilizumab in Combination With Apatinib in Subjects With Unresectable UPS and ASPS
Status: UNKNOWN
Conditions: Sarcoma
Interventions: DRUG: Camrelizumab and Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin C Depigmenattion Versus Conventional Technique
Status: COMPLETED
Conditions: Melanin Hyperpigmentation
Interventions: DIETARY_SUPPLEMENT: vitamin c depigementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Interventions for Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: Resistance exercise|OTHER: Aerobic exercise|OTHER: Usual care during neoadjuvant chemotherapy/Exercise after surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Assess the Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) Effects of EVP-6308 and the Potential of EVP-6308 to Affect the PK Properties of the Antipsychotic Regimen in Subjects With Schizophrenia Currently Receiving Stable Treatment With up to 2 Atypical Antipsychotics
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Drug: EVP-6308|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Analgesic Effects of Melatonin
Status: COMPLETED
Conditions: Analgesia|Antihyperalgesia
Interventions: DRUG: Melatonin 10 mg|DRUG: Melatonin 100 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Does Pulmonary Rehabilitation Improve Frailty?
Status: COMPLETED
Conditions: Disease, Pulmonary
Interventions: OTHER: Pulmonary Rehabilitation|DEVICE: Dynamometer|RADIATION: DEXA|OTHER: Gait Speed Test|DEVICE: Activity Monitor|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pharmacokinetic Study of Bilastine in Children From 2 to < 12 Years of Age With Either Allergic Rhinoconjunctivitis (AR) or Chronic Urticaria (CU)
Status: COMPLETED
Conditions: Allergic Rhinoconjunctivitis|Chronic Urticaria
Interventions: DRUG: Bilastine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of an Acetaminophen/Naproxen Sodium Fixed Combination, Acetaminophen and Naproxen Sodium in Postoperative Dental Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Acetaminophen/Naproxen Sodium Fixed Combination|DRUG: Naproxen Sodium|DRUG: Acetaminophen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Kinesiotaping in Different Directions on Muscle
Status: COMPLETED
Conditions: KINESIOTAPING
Interventions: OTHER: FACILITATION TAPING|OTHER: INHIBITION TAPING|OTHER: PLACEBO TAPING
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Accuracy of MRI-based Patients Matched Instruments vs Jig-based Instruments in Total Knee Arthroplasty (TKA)
Status: COMPLETED
Conditions: Osteoarthritis of Knee
Interventions: DEVICE: Patient matched instruments|DEVICE: Jig based instruments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Breast Cancer BRCA1 Carriers: a Pilot Study
Status: WITHDRAWN
Conditions: BRCA1 Mutation|High-grade Serous Ovarian Cancer|TNBC - Triple-Negative Breast Cancer
Interventions: DRUG: Mifepristone 200 MG|PROCEDURE: Prophylactic mastectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CArdiac Brief INtervention: A Feasibility Study to Promote Engagement With Cardiac Rehabilitation
Status: RECRUITING
Conditions: ST Elevation Myocardial Infarction
Interventions: OTHER: CArdiac Brief INtervention (CABIN)|OTHER: Refined version of CABIN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Benson's Relaxation Technique, Music Therapy for Children With Thalassemia
Status: COMPLETED
Conditions: Thalassemia in Children
Interventions: BEHAVIORAL: Benson's Relaxation technique|BEHAVIORAL: Music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Salusin-alpha - a New Factor in the Pathogenesis of Lipid Abnormalities in Hemodialysis Patients
Status: COMPLETED
Conditions: Renal Failure Chronic Requiring Hemodialysis|Metabolic Syndrome|Diabetes Mellitus Type 2|Hyperlipidemia
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cerebral Autoregulation Monitoring During Cardiac Surgery
Status: COMPLETED
Conditions: Thoracic Surgery|Cardiopulmonary Bypass
Interventions: DRUG: blood pressure maintenance based on cerebral blood flow autoregulation measurement|DEVICE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Drug Interaction Study Between Danicopan and Midazolam, Fexofenadine, and Mycophenolate Mofetil in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Danicopan|DRUG: Midazolam|DRUG: Fexofenadine|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: XP-102 and XP-102 in Combination With Trametinib in Advanced Solid Tumor Patients With a BRAF V600 Mutation
Status: NOT_YET_RECRUITING
Conditions: Cancer|BRAF V600 Mutation|Melanoma|Colorectal Cancer|Thyroid Cancer|Nonsmall Cell Lung Cancer
Interventions: DRUG: XP-102|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation on the Efficacy and Safety of Relizema Cream in Paedriatric Patients
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DEVICE: Relizema cram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hypnosis for Fear of Falling in Older Adults
Status: COMPLETED
Conditions: Rehabilitation|Fear of Falling|Older Adults
Interventions: BEHAVIORAL: Hypnosis|BEHAVIORAL: Rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Sugar-sweetened Beverage Intake Substitution by Water to Prevent Overweight in Mexican Children
Status: COMPLETED
Conditions: Obesity, Childhood
Interventions: BEHAVIORAL: Intervention|BEHAVIORAL: General nutritional recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An mHealth Symptom Management Intervention for Colorectal Cancer Patients (mCOPE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: mHealth Coping Skills Training for Symptom Management (mCOPE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindful Movement Program in Improving Quality of Life in Older Female Breast Cancer Survivors
Status: COMPLETED
Conditions: Anxiety Disorder|Breast Cancer|Cancer Survivor|Cognitive/Functional Effects|Depression|Psychosocial Effects of Cancer and Its Treatment
Interventions: OTHER: questionnaire administration|OTHER: study of socioeconomic and demographic variables|PROCEDURE: CAM exercise therapy|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment|PROCEDURE: stress management therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Covalent Menin Inhibitor BMF-219 in Adult Patients With KRAS Driven Non-Small Cell Lung Cancer, Pancreatic Cancer, and Colorectal Cancer
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Pancreatic Cancer|Colorectal Cancer|NSCLC|PDAC|CRC|Relapsed Cancer|Refractory Cancer|Stage III Pancreatic Cancer|Stage IV Pancreatic Cancer|Stage III Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer|Stage III Colorectal Cancer|Stage IV Colorectal Cancer|Stage III NSCLC|Stage IV NSCLC|KRAS Mutation-Related Tumors
Interventions: DRUG: BMF-219
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ES-481 for Uncontrolled Glioma-Associated Epilepsy and Assessment for Potential Anti-Tumorigenic Effect in Patients With Isocitrate Dehydrogenase 1 (IDH1) Mutant Tumors
Status: WITHDRAWN
Conditions: Epilepsy; Seizure
Interventions: DRUG: ES-481
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation and Comparison of 2 Cosmetic Investigational Products in Adults With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: OTHER: Topical Ointment with L. reuteri|OTHER: Topical Ointment without L. reuteri
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Preventing Urinary Tract Infection Post-Surgery
Status: COMPLETED
Conditions: Urinary Tract Infection
Interventions: DRUG: Cranberry powder capsules|DRUG: Placebo powder capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Three Cannulas for Hysterosalpingography
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: HSG with acorn-tipped cannula|PROCEDURE: HSG with cervical vacuum cup|PROCEDURE: HSG with balloon catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Chronic Low Back Pain.
Status: COMPLETED
Conditions: Back Pain
Interventions: DRUG: Buprenorphine transdermal delivery system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Valuation of the Evolution of Passive Mobility in the Spastic Upper Limb After Injection of Abobotulinumtoxin(Dysport®)
Status: UNKNOWN
Conditions: Spasticity, Muscle|Stroke Sequelae|Movement Disorders
Interventions: DRUG: Abobotulinum toxin A
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of the Transpulmonary Pressure on Right Ventricle Function in Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome
Interventions: OTHER: Pneumotachograph|OTHER: Esophageal catheter|OTHER: Transthoracic and / or transesophageal cardiac ultrasound|OTHER: Electrical impedance tomography (EIT) for pediatric patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Outcomes of Colonoscopy With Non-anesthesiologist Administered Propofol
Status: COMPLETED
Conditions: Colo-rectal Cancer|Colon Adenoma|ADR
Interventions: PROCEDURE: Sedation directed by an endoscopist|PROCEDURE: Sedation directed by an anesthesiologist
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Parent-Led Cognitive-Behavioral Teletherapy for Anxiety in Youth With ASD
Status: COMPLETED
Conditions: Cognitive Behavioral Therapy|Autism Spectrum Disorder|Anxiety Disorders|Obsessive-Compulsive Disorder|Social Anxiety Disorder|Generalized Anxiety Disorder|Specific Phobia
Interventions: BEHAVIORAL: Cognitive Behavioral Teletherapy LTA|BEHAVIORAL: Cognitive Behavioral Teletherapy STA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FOLFOXIRI Chemotherapy Alone as Neoadjuvant Treatment for Circumferential Radial Margin (CRM) Positive Rectal Cancer
Status: WITHDRAWN
Conditions: Rectal Cancer
Interventions: DRUG: FOLFOXIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Retention Rate, Persistence and Adherence in Population of Spondylarthritis (Ankylosing Spondylitis and Psoriatic Arthritis) Patients Treated With Adalimumab in Routine Clinical Settings in Russian Federation
Status: COMPLETED
Conditions: Spondylarthritis|Psoriatic Arthritis|Ankylosing Spondylitis (AS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pan-RAS Inhibitor YL-17231 in Patients With Advanced Solid Tumors Harboring Mutations in KRAS, HRAS, or NRAS
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: YL-17231
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Enterovirus 71（EV71） Inactivated Vaccine in Children Aged 36-71 Months
Status: COMPLETED
Conditions: Hand, Foot and Mouth Disease
Interventions: BIOLOGICAL: 36-71 months old children-experimental EV71 vaccine.|BIOLOGICAL: 36-71 months old children-control EV71 vaccine.|BIOLOGICAL: 6-35 months old children-experimental EV71 vaccine.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Induction Chemotherapy Before or After Preoperative Chemoradiotherapy and Surgery for Locally Advanced Rectal Cancer
Status: COMPLETED
Conditions: Rectal Neoplasms|Rectal Cancer Stage II|Rectal Cancer Stage III
Interventions: DRUG: Induction Chemotherapy arm A|RADIATION: Radiation arm A|RADIATION: Radiation arm B|DRUG: Chemotherapy arm B|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Mesenchymal Stem Cells For Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome
Interventions: BIOLOGICAL: Allogeneic Bone Marrow-Derived Human Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Demonstration of Near Zero Antibiotic Prescribing for Acute Bronchitis
Status: COMPLETED
Conditions: Bronchitis|Cough
Interventions: BEHAVIORAL: Demonstration of near zero antibiotic prescribing for patients with acute bronchitis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of rTMS on the Anxiety State of Older Patients With GAD
Status: NOT_YET_RECRUITING
Conditions: Generalized Anxiety Disorder
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation|DEVICE: Sham Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 2.5 Versus 5 Minutes Trial
Status: RECRUITING
Conditions: Hypotension
Interventions: OTHER: Oscillometric blood pressure monitoring at 2.5-minute intervals|OTHER: Oscillometric blood pressure monitoring at 5-minute intervals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Muscle Strengthening Exercises and Global Stretching in Elderly
Status: COMPLETED
Conditions: Osteoporosis|Senile Osteopenia
Interventions: OTHER: Muscle stretching and Strength Training|OTHER: Educated about physical exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of RVU120 for Treatment of Relapsed/Refractory AML
Status: RECRUITING
Conditions: Acute Myeloid Leukemia (AML)|High-risk Myelodysplastic Syndrome
Interventions: DRUG: RVU120
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fusion or no Fusion After Decompression of the Spinal Cord in Patients With Degenerative Cervical Myelopathy
Status: RECRUITING
Conditions: Cervical Spondylotic Myelopathy
Interventions: PROCEDURE: Muscle preserving selective laminectomy|PROCEDURE: Laminectomy with instrumented fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of a High-intensity Signal of the Oculomotor Nerve on T2 MRI Sequence in Patients With Ophthalmoplegia
Status: COMPLETED
Conditions: Ophthalmoplegia
Interventions: DIAGNOSTIC_TEST: MRI T2 sequence of the oculomotor tract
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Water Biking in Hot Versus Neutral Water for Heat Acclimatation
Status: COMPLETED
Conditions: Healthy|Heat Exposure
Interventions: OTHER: Water Biking in hot water condition|OTHER: Water Biking in neutral water condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Radiation Therapy and Either Capecitabine or Fluorouracil With or Without Oxaliplatin Before Surgery in Treating Patients With Resectable Rectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: capecitabine|DRUG: fluorouracil|DRUG: oxaliplatin|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relation of Catechol-O-methyltransferase (COMT) Genotype and Response to Cognitive Remediation Schizophrenia
Status: UNKNOWN
Conditions: Chronic Schizophrenia
Interventions: BEHAVIORAL: Cognitive remediation therapy|GENETIC: COMT Genotyping
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Freeze Dried Strawberry Powder Supplementation on Cardiovascular Risk Factors and Gut Microbiome
Status: TERMINATED
Conditions: Cardiovascular Risk Factor
Interventions: DIETARY_SUPPLEMENT: Strawberry powder|DIETARY_SUPPLEMENT: Placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing the Benefits and Harms of Three Types of Weight Loss Surgery -- The PCORnet® Bariatric Study
Status: COMPLETED
Conditions: Obesity|Bariatrics|Body Weight|Diabetes Mellitus|Weight Loss|Roux-en-Y Gastric Bypass|Gastric Bypass
Interventions: PROCEDURE: Roux-en-y gastric bypass (RYGB) - historical|PROCEDURE: Adjustable gastric banding (AGB) - historical|PROCEDURE: Sleeve gastrectomy (SG) - historical
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Succinylcholine vs Rocuronium for Prehospital Emergency Intubation
Status: COMPLETED
Conditions: Coma|Major Trauma|Respiratory Distress|Shock
Interventions: DRUG: Succinylcholine : 1mg/kg|DRUG: Rocuronium : 1.2 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Laryngotracheal Stenosis Using Mesenchymal Stem Cells
Status: COMPLETED
Conditions: Tracheal Stenosis|Laryngeal Stenosis|Mesenchymal Stem Cells
Interventions: BIOLOGICAL: Olfactory mucosa-derived mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Integration of Indigenous Healing With Principals of Seeking Safety for Treatment of Indigenous Patients With a History of Trauma and Active Substance Use Disorder.
Status: COMPLETED
Conditions: Substance Use Disorders|Post-Traumatic Stress Disorder|Intergenerational Trauma
Interventions: OTHER: Indigenous Healing and Seeking Safety
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Recombinant Human Serum Albumin in Patients With Liver Cirrhosis and Ascites Subjects
Status: COMPLETED
Conditions: Hepatic Ascites
Interventions: DRUG: Recombinant Human Serum Albumin|DRUG: Human serum albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Micronutrient and Additive Modifications May Optimize Diet To Health
Status: RECRUITING
Conditions: Ulcerative Colitis|Diet Habit|Microbial Colonization
Interventions: OTHER: Normal diet|DIETARY_SUPPLEMENT: E400 elimination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Prucalopride Treatment for Refractory Gastro-esophageal Reflux Disease
Status: UNKNOWN
Conditions: GERD
Interventions: DRUG: Prucalopride|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Effectiveness of Infliximab (Remicade) in Patients With Juvenile Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis, Juvenile
Interventions: DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Within Subject Variability Study of ER Torsemide 20 mg Tablet in Healthy Subjects
Status: COMPLETED
Conditions: Congestive Heart Failure|Chronic Kidney Diseases
Interventions: DRUG: Demadex 20mg Tablet|DRUG: ER Torsemide 20mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Efficacy of Low FODMAP Versus Low Lactose Diet in IBS Patients
Status: COMPLETED
Conditions: IBS - Irritable Bowel Syndrome
Interventions: OTHER: Low Lactose Diet|OTHER: Low FODMAP Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Within-subject Variability of Insulin Detemir in Children and Adolescents With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin detemir|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SMS Reminders to Strengthen Demand for HPV Vaccination in Georgia
Status: UNKNOWN
Conditions: HPV, Human Papillomavirus Viruses, Human Papilloma Virus Vaccine
Interventions: BEHAVIORAL: SMS reminder for the HPV vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Platelet-Rich Plasma (PRP) for Treatment of Symptomatic Lumbar Facet Syndrome of the Spine
Status: COMPLETED
Conditions: Platelet-Rich Plasma
Interventions: BIOLOGICAL: Autologous platelet rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Oligonol Supplementation to Promote Cardiovascular Health
Status: COMPLETED
Conditions: Cardiovascular Health
Interventions: DIETARY_SUPPLEMENT: Oligonol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Letrozole on Precocious Puberty Due to McCune Albright Syndrome
Status: COMPLETED
Conditions: McCune Albright Syndrome|Polyostotic Fibrous Dysplasia|Precocious Puberty
Interventions: DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of Bowel Cleansing Regimens Prior to Colonoscopy
Status: ACTIVE_NOT_RECRUITING
Conditions: Patients Undergoing Elective Colonoscopy
Interventions: DRUG: polyethylene glycole (PEG) solution|DRUG: sodium picosulphate and magnesium citrate solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Follow-up Trial of Proglucamune® in the Treatment of Protective Qi Deficiency, a TCM Condition
Status: COMPLETED
Conditions: Protective Qi Insufficiency (a Condition Term From TCM)
Interventions: DIETARY_SUPPLEMENT: beta glucan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gag Therapy for Recurrent Urinary Tract Infection Assessing Comparability to International Nitrofurantoin Gold Standard Study
Status: RECRUITING
Conditions: Recurrent Urinary Tract Infection
Interventions: DEVICE: Ialuril 50ml Prefill|DRUG: Nitrofurantoin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Patient Satisfaction, Peri-implant Parameters and Crestal Bone Evaluation of PEEK (Polyetheretherketone) Abutments Versus Zirconium Abutments Restored With PEEK Based Superstructure
Status: UNKNOWN
Conditions: Patients Satisfaction
Interventions: DEVICE: PEEK implant abutment|DEVICE: Zirconia abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Early Administration of Dapagliflozin in STEMI Patients With LV Systolic Dysfunction
Status: UNKNOWN
Conditions: STEMI - ST Elevation Myocardial Infarction|Left Ventricular Systolic Dysfunction
Interventions: DRUG: Dapagliflozin 10Mg Tab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bronchoscopic Approach to the Peripheral Lung Nodule - Endobronchial Ultrasound, Electromagnetic Navigation and Cryobiopsy
Status: COMPLETED
Conditions: Lung Nodules
Interventions: PROCEDURE: cryobiopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single and Multiple Dosing Study in Hemodialysis Patients With Hyperphosphatemia in Japan
Status: COMPLETED
Conditions: Chronic Kidney Disease|Hyperphosphatemia Undergoing Hemodialysis
Interventions: DRUG: ASP3325
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cost-effectiveness, Volar Locking Plate or Non-operative Treatment Distal Radius Fracture
Status: ACTIVE_NOT_RECRUITING
Conditions: Radius Fractures|Aged|Cost-Benefit Analysis|Wrist Fracture|Quality of Life|Wrist Injuries|Postoperative Complications|Health Care Utilization
Interventions: PROCEDURE: Volar Locking Plate|PROCEDURE: Plaster Cast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of a Mentor-based, Supportive-expressive Program on Survival in Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Metastatic Breastcancer
Interventions: BEHAVIORAL: Be Resilient to Breast Cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PRISMA Study (Prospective, Randomized Trial on Intensive Self-Monitoring Blood Glucose Management Added Value in Non-Insulin Treated Type 2 Diabetes Mellitus Patients)
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DEVICE: Accu-Chek Aviva Meter|DEVICE: Accu-Chek Aviva Meter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pain Study Using Intermittent Bupivacain Injections After Breast Reconstruction With DIEP Flap
Status: COMPLETED
Conditions: Breast Reconstruction
Interventions: DRUG: bupivacain|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Prelieve Trial - Pilot Study to Assess Safety and Efficacy of a Novel Atrial Flow Regulator (AFR) in Heart Failure Patients
Status: COMPLETED
Conditions: Heart Failure Low Output|Heart Failure
Interventions: DEVICE: Occlutech AFR device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT