pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Alternative Treatment to Reduce Chronicity in OCD: Research Into Brain Response and Adequacy of Treatment
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Inference Based Approach (IBA)|BEHAVIORAL: Cognitive Behavioural Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hepatectomy Versus Chemoembolization for Resectable Hepatocellular Carcinoma Beyond Milan Criteria
Status: UNKNOWN
Conditions: Resectable Hepatocellular Carcinoma Beyond Milan Criteria
Interventions: PROCEDURE: Chemoembolization and Response-Dependent Resection|PROCEDURE: Immediate Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Carbohydrate in DM Patients Undergoing Total Knee Arthroplasty
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: DIETARY_SUPPLEMENT: Carbohydrate-rich drink|DIETARY_SUPPLEMENT: 10% dextrose solution mixed with insulin 16 unit 100 mL/h
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Behaviorally Enhanced Counseling on Nicotine Dependence (BEACON) Trial.
Status: COMPLETED
Conditions: Smoking
Interventions: BEHAVIORAL: Counseling|BEHAVIORAL: Self-help guide|DRUG: Pharmacotherapy|BEHAVIORAL: Genetic feedback, verbal|BEHAVIORAL: Genetic feedback, printed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CellFX Treat & Resect Low-Risk BCC Feasibility Study
Status: COMPLETED
Conditions: BCC - Basal Cell Carcinoma|BCC|Excision Margin
Interventions: DEVICE: CellFX System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Anxiety on Perioperative Pain: Patient and Provider Perception
Status: COMPLETED
Conditions: Pain
Interventions: OTHER: preoperative questionnaire|OTHER: PACU questionnaire|OTHER: Postoperative questionnaire|OTHER: Postoperative questionnaire- Obstetrician|OTHER: Postoperative questionnaire- anesthesiologist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Outcome and Safety of Lithium, Divalproex and Risperidone for Mania in Children and Adolescents
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Lithium carbonate|DRUG: Valproate|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fulvestrant and Ipatasertib for Advanced HER-2 Negative and Estrogen Receptor Positive (ER+) Breast Cancer Following Progression on First Line CDK 4/6 Inhibitor and Aromatase Inhibitor
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Ipatasertib|DRUG: Fulvestrant|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Testing of Adolescent Twelve-Step Facilitation
Status: COMPLETED
Conditions: Alcohol Abuse|Alcohol Dependence|Drug Abuse|Drug Dependence
Interventions: BEHAVIORAL: Integrated Twelve-Step Facilitation|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tiotropium Once Daily 18 Mcg Versus Salmeterol Twice Daily 50 Mcg on Time to First Exacerbation in COPD Patients.
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium bromide|DRUG: Salmeterol|DRUG: Placebo Salmeterol|DRUG: Placebo Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Three Antiemetics in Preventing Nausea and Vomiting
Status: COMPLETED
Conditions: Nausea and Vomiting
Interventions: DRUG: tropisetron|DRUG: metoclopramide|DRUG: dexamethasone|OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy With or Without Celecoxib in Treating Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFIRI regimen|DRUG: capecitabine|DRUG: celecoxib|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Telehealth-enabled Integrated Palliative Care for People With Dementia
Status: ACTIVE_NOT_RECRUITING
Conditions: Dementia of Alzheimer Type|Alzheimer Disease|Frontotemporal Degeneration|Lewy Body Dementia|Vascular Cognitive Impairment|Vascular Dementia|Mixed Dementia
Interventions: OTHER: Telehealth Integrated Primary Care (TIPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preventive TREatment of Dry Eye in Patients Receiving Repeated Intravitreal Injections for Age-related Macular Degeneration
Status: RECRUITING
Conditions: Dry Eye Syndromes|Age-Related Macular Degeneration
Interventions: DEVICE: Preservative-free ophtalmic lubricant emulsion|OTHER: Routine treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized, Controlled Trial of S-adenosylmethionine in Alcoholic Liver Disease
Status: COMPLETED
Conditions: Alcoholic Hepatitis
Interventions: OTHER: Placebo|DIETARY_SUPPLEMENT: SAMe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, One-arm and Open Clinical Study of Obinutuzumab in the Treatment of Pediatric Primary Immune Thrombocytopenia (ITP)
Status: RECRUITING
Conditions: Immune Thrombocytopenia|Treatment
Interventions: DRUG: Obinutuzumab Injection [Gazyva]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phenylalanine-free Diet for Patients With Secondary Hyperphenylalaninemia in ICU
Status: RECRUITING
Conditions: Non-Phenylketonuric Hyperphenylalaninemia
Interventions: DIETARY_SUPPLEMENT: Phenylalanine-free milk
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Changes in Visual Acuity in Patients With Diabetic Macular Edema (DME) Starting Treatment With an Approved Anti-VEGF Therapy
Status: COMPLETED
Conditions: Ophthalmology|Macular Edema|Macular Degeneration
Interventions: DRUG: Ranibizumab (or other DME treatment)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Androgen Annihilation in High-Risk Biochemically Relapsed Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Apalutamide|DRUG: LHRH Analogue|DRUG: Abiraterone Acetate|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prucalopride Versus Placebo in Gastroparesis
Status: COMPLETED
Conditions: Gastroparesis|Diabetes Mellitus
Interventions: DRUG: Prucalopride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of GS-9876 in Participants With Active Rheumatoid Arthritis on Background Therapy With Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: GS-9876|DRUG: Filgotinib|DRUG: GS-9876 placebo|DRUG: Filgotinib placebo|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Tobacco Treatment Intervention in Reducing Surgical Complications in Patients With Newly Diagnosed Lung Cancer Who Smoke Cigarettes
Status: TERMINATED
Conditions: Lung Carcinoma
Interventions: DRUG: Varenicline|DRUG: Placebo|OTHER: Tobacco Cessation Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Toradol to Reduce Ureteroscopic Symptoms Trial
Status: COMPLETED
Conditions: Urinary Lithiasis|Kidney Diseases|Kidney Stone|Pain, Postoperative
Interventions: DRUG: Toradol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Children With Different Formulations of GSK Biologicals' 11 Valent Pneumococcal Conjugate Vaccine
Status: COMPLETED
Conditions: Streptococcal Infections
Interventions: BIOLOGICAL: Pneumococcal (vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Daily Adaptive Radiation Therapy an Individualized Approach for Carcinoma of the Cervix
Status: RECRUITING
Conditions: Cervical Cancer by FIGO Stage 2018
Interventions: DEVICE: Varian Ethos Adaptive Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Bladder Training and Pelvic Floor Muscle Training on the Symptomatology of Overactive Bladder Syndrome
Status: UNKNOWN
Conditions: Overactive Bladder Syndrome
Interventions: OTHER: Bladder Training|OTHER: TMAP|OTHER: Bladder Training + TMAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Evidence-based Psychological Treatments for Emotional Disorders
Status: COMPLETED
Conditions: Anxiety Disorders|Depression|Somatoform Disorders|Common Mental Disorders
Interventions: OTHER: Brief individual psychotherapy|OTHER: Brief group psychotherapy|OTHER: Combined intervention|OTHER: Minimum psychological intervention|OTHER: Usual treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of RLS103 in a Clinical Model of Photosensitive Epilepsy
Status: TERMINATED
Conditions: Epilepsy
Interventions: DRUG: High dose RLS103|DRUG: placebo inhaled powder|DRUG: Low dose RLS103
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Whole Food Plant-based Diet Effect on Obstructive Sleep Apnea
Status: RECRUITING
Conditions: Obstructive Sleep Apnea|Daytime Sleepiness
Interventions: BEHAVIORAL: Whole Food Plant-Based Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 177Lu Radiolabeled Monoclonal Antibody HuJ591 (177Lu-J591) and Ketoconazole in Patients With Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: 177Lu-J591|DRUG: Ketoconazole|DRUG: Hydrocortisone|DRUG: 111In-J591
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin E Supplementation for Children With Transfusion Dependent Beta Thalassemia on Different Iron Chelation Regimen
Status: COMPLETED
Conditions: Beta-Thalassemia
Interventions: DIETARY_SUPPLEMENT: vitamin E|OTHER: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eculizumab Therapy for Dense Deposit Disease and C3 Nephropathy
Status: COMPLETED
Conditions: Dense Deposit Disease|Membranoproliferative Glomerulonephritis
Interventions: DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Video Game Exercise on Dynamic Balance and Gait in Individuals With Huntington's Disease
Status: COMPLETED
Conditions: Huntington's Disease
Interventions: OTHER: Video game exercise using Dance Dance Revolution|OTHER: hand-held video game
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Pectoral Nerves Blockade for Persistent Pain After Breast Cancer Surgery
Status: UNKNOWN
Conditions: Persistent Pain After Breast Cancer Surgery
Interventions: PROCEDURE: PECS block|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Determination of Target of Adequate Partial Neuromuscular Blockade for Electrophysiologic Monitoring During Microvascular Decompression Surgery
Status: COMPLETED
Conditions: Hemifacial Spasm|Microvascular Decompression|Neuromuscular Blockade
Interventions: OTHER: TOF count-guided partial NMB|OTHER: T1/Tc guided partial NMB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Cetuximab & Concomitant-Boost Accelerated RT in Patients With Locally Advanced Oropharynx Squamous Cell Carcinoma.
Status: UNKNOWN
Conditions: Oropharyngeal Neoplasms
Interventions: DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Andecaliximab Combined With Nivolumab Versus Nivolumab Alone in Adults With Unresectable or Recurrent Gastric or Gastroesophageal Junction Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Andecaliximab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulsed Electromagnetic Fields for Multiple Chemical Sensitivity
Status: COMPLETED
Conditions: Multiple Chemical Sensitivity
Interventions: DEVICE: Pulsed electromagnetic fields|DEVICE: w/o pulsed electromagnetic fields
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study Evaluating Induction Chemotherapy Followed by Chemoradiotherapy Compared to Standard Chemoradiotherapy for Locally Advanced SCCA
Status: RECRUITING
Conditions: Anal Cancer
Interventions: DRUG: induction chemotherapy (mDCF)|DRUG: Concomitant chemotherapy (Capecitabin + Mitomycin-C)|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Percutaneous Electrolysis, Percutaneous Neuromodulation and Eccentric Exercise
Status: COMPLETED
Conditions: Supraspinatus Tendinitis
Interventions: OTHER: EPTE® group|OTHER: Dry needling group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin (BI 10773) Comprehensive add-on Study in Japanese Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Metformin|DRUG: BI 10773|DRUG: Placebo (low dose)|DRUG: BI 10773|DRUG: Placebo (high dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Digital Interventions in Neurorehabilitation: iTALKbetter
Status: COMPLETED
Conditions: Stroke|Aphasia|Anomia
Interventions: OTHER: iTALKbetter: deterministic|OTHER: iTALKbetter: reactive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effect of Meibomian Gland Probing on Ocular Surface in Ocular Rosacea
Status: WITHDRAWN
Conditions: Meibomian Gland Dysfunction
Interventions: PROCEDURE: meibomian gland probing|PROCEDURE: Left eye Meibomian Gland Probing Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Posterior Tibial Artery Catheterization
Status: COMPLETED
Conditions: Arterial Catheterization
Interventions: PROCEDURE: posterior tibial artery|PROCEDURE: radial artery|PROCEDURE: dorsalis pedis artery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Impacts of Exercise on Prognostic Biomarkers in Lung Cancer Patients
Status: COMPLETED
Conditions: Extensive Stage Small Cell Lung Cancer|Healthy, no Evidence of Disease|Limited Stage Small Cell Lung Cancer|Recurrent Non-small Cell Lung Cancer|Recurrent Small Cell Lung Cancer|Stage IA Non-small Cell Lung Cancer|Stage IB Non-small Cell Lung Cancer|Stage IIA Non-small Cell Lung Cancer|Stage IIB Non-small Cell Lung Cancer|Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: BEHAVIORAL: exercise intervention|PROCEDURE: standard follow-up care|PROCEDURE: quality-of-life assessment|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial of CRB4101 in Healthy Subjects
Status: RECRUITING
Conditions: Healthy Adult Subjects
Interventions: DRUG: CRB4101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Diagnostic Accuracy of Contrast Enhanced Dual Energy Mammography Imaging in Comparison to CE-MRI
Status: COMPLETED
Conditions: Breast Cancer Diagnosis
Interventions: DEVICE: CONTRAST ENHANCED DUAL ENERGY (CEDEM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Uterine Prolapse Procedures - Randomized Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Uterovaginal Prolapse
Interventions: PROCEDURE: Uterosacral ligament suspension|PROCEDURE: Uphold® LITE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Contribution of Incretin Hormones to Post-prandial Glucose Metabolism After Roux-en-Y Gastric Bypass
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Exendin 9, 39|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial of Use of Autologous Bone Marrow Stem Cells Seeded on Porous Tricalcium Phosphate Matrix and Demineralized Bone Matrix in Patients With Osteonecrosis
Status: UNKNOWN
Conditions: Osteonecrosis of Jaw
Interventions: BIOLOGICAL: MSC construct for Osteonecrosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Functional Magnetic Resonance Imaging (fMRI) in Patients Who Speak Two Languages Fluently
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioma|Glioma of Brain|Glioma of Spinal Cord
Interventions: BEHAVIORAL: Multilingual Aphasia Examination|DIAGNOSTIC_TEST: Language paradigms + RS fMRI|DIAGNOSTIC_TEST: Language paradigms + RS fMRI + one anatomical sequence
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sleep Disturbance in MCI: A Study of a Cognitive Behavioural Therapy Digital Intervention
Status: COMPLETED
Conditions: Cognitive Dysfunction|Insomnia|Mild Cognitive Impairment|Cognitive Disorder|Sleep Wake Disorders
Interventions: DEVICE: digital CBT-I|OTHER: Online Sleep Health Education package
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retinal Imaging by Adaptive Optics in Healthy Eyes and During Retinal and General Diseases
Status: COMPLETED
Conditions: Retinal Dystrophies|Age-related Macular Degeneration|Arterial Hypertension|Diabetes|Traumatic Retinopathy|Toxic Retinopathies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Evaluation of HPT Treated Rigid Contact Lenses Made From Roflufocon D
Status: COMPLETED
Conditions: Ametropia
Interventions: DEVICE: roflufocon D contact lenses|DEVICE: RGP contact lenses made from roflufocon D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HealthCall:Brief Intervention to Reduce Non-injecting Drug Use in HIV Primary Care Clinics
Status: COMPLETED
Conditions: Mental and Behavioral Disorders Due to Harmful Drug Use
Interventions: BEHAVIORAL: HealthCall and Motivational Interviewing|BEHAVIORAL: Motivational Interviewing (MI)|BEHAVIORAL: HIV/AIDS health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pimecrolimus Cream 1% Twice-Daily to Once-Daily Dosing in the Management of Atopic Dermatitis in Pediatric Subjects
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Pimecrolimus|DRUG: Pimecrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)
Status: RECRUITING
Conditions: Sleep Apnea Syndrome|Obstructive Sleep Apnea|COPD|Overlap Syndrome|Quality of Life|Neurocognitive Function|Sleepiness|Elderly|Positive Airway Pressure
Interventions: DEVICE: Positive airway pressure|OTHER: Conservative care (control arm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cell Surface Markers and Lymphoid Cell Distribution on the Arterial Tissue Repair (ECLAR)
Status: UNKNOWN
Conditions: Injury of Radial Artery at Wrist and Hand Level|Injury; Ulnar Artery, Hand and Wrist
Interventions: PROCEDURE: vessel microsurgery|PROCEDURE: tendon repair|PROCEDURE: nerve microsurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Photoallergic Potential of PEP005 (Ingenol Mebutate) Gel, 0.01% in Healthy Volunteers
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: PEP005 (ingenol mebutate) Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Investigate The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of RO7248824 In Participants With Angelman Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Angelman Syndrome
Interventions: DRUG: RO7248824
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritional, Metabolic and Respiratory Status in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Diabetes
Interventions: PROCEDURE: Urinary collect|PROCEDURE: Continuous Glucose Monitoring System (CGMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Efficacy and Safety Study of Intetumumab (CNTO 95) in Participants With Metastatic Hormone Refractory Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Docetaxel|DRUG: Prednisone|BIOLOGICAL: Intetumumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Local Infiltration Analgesia After Abdominal Hysterectomy
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: ropivacaine, ketorelac and epinephrine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Neurocomputational Mechanisms of Explore-Exploit Decision Making in Older Adults
Status: RECRUITING
Conditions: Healthy Aging
Interventions: DEVICE: Continuous theta burst transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A First-in-human Study of Single Doses of PF-07328948 Which is Given to Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-07328948|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The SUGAR Study: (SBRT and Ultrashort GnRH Antagonist-Relugolix) for Clinicogenomic Unfavorable Intermediate Risk Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Relugolix 120 MG [Orgovyx]|RADIATION: SBRT standard of care radiotherapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surface Landmarks and C-length as Predictors of Depth of Right IJV Catheter Insertion: A TEE-Guided Study
Status: UNKNOWN
Conditions: Catheterization, Central Venous|Echocardiography, Transesophageal|Anatomic Landmarks|Radiography
Interventions: PROCEDURE: Catheterization of internal jugular vein
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Single-Dose Pharmacokinetics (PK) Study of Novel Neurogenic Compound NSI-189
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: NSI-189 Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CBDV vs Placebo in Children and Adults up to Age 30 With Prader-Willi Syndrome (PWS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Prader-Willi Syndrome
Interventions: DRUG: CBDV Compound|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-H3733 in Subjects With Chronic Hepatitis B Virus Infection
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: ABI-H3733|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Insertable Cardiac Monitor-Guided Early Intervention to Reduce Atrial Fibrillation Burden Following Catheter Ablation
Status: RECRUITING
Conditions: Atrial Fibrillation|Cardiovascular Diseases|Heart Diseases|Arrhythmias, Cardiac|Pathologic Processes
Interventions: DEVICE: Insertable Cardiac Monitor or external non-invasive LT-ECG patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Function of Older Citizens During Municipality-based Rehabilitation
Status: COMPLETED
Conditions: Aging|Rehabilitation|Frailty|Sarcopenia|Fractures, Bone|Musculoskeletal Pain|Musculoskeletal Diseases|Musculoskeletal Injury|Muscle Weakness|Weakness, Muscle
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preoperative Herceptin and Navelbine for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Stage II Breast Cancer|Stage III Breast Cancer
Interventions: DRUG: Herceptin|DRUG: Navelbine|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of Pioglitazone-Azilsartan in Subjects With Type 2 Diabetes Mellitus
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DRUG: Pioglitazone and Azilsartan|DRUG: Pioglitazone and Azilsartan|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DCS Study in Extremely Premature Newborns
Status: UNKNOWN
Conditions: Premature Birth|Extremely Low Birth Weight|Infant, Small for Gestational Age|Intracerebral Hemorrhage
Interventions: DEVICE: Diffuse Correlation Spectroscopy (DCS)|DEVICE: Amplitude Integrated Electroencephalography (aEEG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safety Feasibility and Effect of TTFields (150 kHz) Concomitant With Gemcitabine or Concomitant With Gemcitabine Plus Nab-paclitaxel for Front-line Therapy of Advanced Pancreatic Adenocarcinoma (PANOVA)
Status: UNKNOWN
Conditions: Pancreatic Adenocarcinoma
Interventions: DEVICE: NovoTTF-100L|DRUG: Gemcitabine|DRUG: nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed Alone as Salvage Treatment in Metastatic Colorectal Cancer Patients Who Were Failed After Standard Chemotherapy: A Phase II Single Arm Prospective Study
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid (TXA) Versus Epsilon Aminocaproic Acid (EACA) Versus Placebo for Spine Surgery
Status: COMPLETED
Conditions: Scoliosis
Interventions: DRUG: Tranexamic Acid|DRUG: Normal Saline|DRUG: Epsilon aminocaproic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Flavopiridol in Treating Children With Relapsed or Refractory Solid Tumors or Lymphomas
Status: COMPLETED
Conditions: Recurrent Childhood Brain Stem Glioma|Recurrent Childhood Cerebellar Astrocytoma|Recurrent Childhood Cerebral Astrocytoma|Recurrent Childhood Ependymoma|Recurrent Childhood Large Cell Lymphoma|Recurrent Childhood Liver Cancer|Recurrent Childhood Lymphoblastic Lymphoma|Recurrent Childhood Malignant Germ Cell Tumor|Recurrent Childhood Medulloblastoma|Recurrent Childhood Rhabdomyosarcoma|Recurrent Childhood Small Noncleaved Cell Lymphoma|Recurrent Childhood Soft Tissue Sarcoma|Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor|Recurrent Childhood Visual Pathway and Hypothalamic Glioma|Recurrent Childhood Visual Pathway Glioma|Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Recurrent Neuroblastoma|Recurrent Osteosarcoma|Recurrent Retinoblastoma|Recurrent Wilms Tumor and Other Childhood Kidney Tumors|Recurrent/Refractory Childhood Hodgkin Lymphoma|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: alvocidib|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STReetlab Assessment Tool of Activities Daily Living in Glaucoma Patient
Status: NOT_YET_RECRUITING
Conditions: Optic Neuropathy
Interventions: BEHAVIORAL: Pilot Phase: standardized behavioral task|BEHAVIORAL: Validation Phase: standardized behavioral task
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Deciphering Antitumour Response and Resistance With INtratumour Heterogeneity
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: MPDL3280A|DRUG: Vemurafenib|DRUG: Alectinib|DRUG: Trastuzumab emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Performance of the MINITAC◊ Titanium 2.0 Suture Anchor
Status: COMPLETED
Conditions: Hallux Valgus Repairs|Medial or Lateral Instability Repairs/Reconstructions|Achilles Tendon Repairs/Reconstructions|Midfoot Reconstructions|Metatarsal Ligament/Tendon Repairs/Reconstructions|Scapholunate Ligament Reconstructions|Ulnar or Radial Collateral Ligament Reconstructions|Lateral Epicondylitis Repair|Biceps Tendon Reattachment
Interventions: DEVICE: MINITAC Ti 2.0 suture anchor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Safety, Pharmacokinetics and Efficacy of Ceftazidime and Avibactam (CAZ-AVI ) Compared With Cefepime in Children From 3 Months to Less Than 18 Years of Age With Complicated Urinary Tract Infections (cUTIs)
Status: COMPLETED
Conditions: Complicated Urinary Tract Infections
Interventions: DRUG: Ceftazidime -avibactam|DRUG: Cefepime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sarpogrelate On the Nephropathy in Type 2 Diabetes (SONATA Study)
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: Anplag(Sarpogrelate)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Pediatric Supracondylar Humeral Fractures With Novel Kirschner Wire Fixation Devices
Status: UNKNOWN
Conditions: Supracondylar Humerus Fracture
Interventions: DEVICE: Novel K-wire fixation devices
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Risk Population of Cardiovascular Disease in Hubei Province Screening and Intervention Program
Status: RECRUITING
Conditions: Cardiovascular Diseases|Diabetes Mellitus, Type 2|Coronary Disease
Interventions: BEHAVIORAL: phone calls and encouraging patients' lifestyle change and medication adherence|DRUG: Statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Atrophic Nonunion by Preosteoblast Cells
Status: COMPLETED
Conditions: Pseudarthrosis|Fractures, Ununited
Interventions: PROCEDURE: percutaneous autologous preosteoblast cells implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Drug-drug Interaction Between FosD and Verapamil When Taken Together in Healthy Volunteers
Status: COMPLETED
Conditions: Drug Drug Interactions|Healthy Volunteers
Interventions: DRUG: FOSTAMATIN|DRUG: Verapamil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Parafricta Bootees vs UK Standard Care to Prevent Heel Pressure Ulcers
Status: TERMINATED
Conditions: Pressure Ulcer|Pressure Injury|Heel Ulcer
Interventions: DEVICE: Parafricta bootees
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acceptability and Feasibility of Micronutrient Powders Versus Iron Syrup for Anemia Prevention in Young Children
Status: COMPLETED
Conditions: Anemia
Interventions: DIETARY_SUPPLEMENT: Iron and Folic Acid (IFA)|DIETARY_SUPPLEMENT: Micronutrient Powders (MNP)|BEHAVIORAL: Iron Plus Strategy Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Compare Fallopian Tube Cells Collected by Cytuity With Removed Ovarian/Tubal Tissue to Determine Presence of Malignancy
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Ovarian Neoplasms|Ovary Cancer|Fallopian Tube Neoplasms|Fallopian Tube Adenocarcinoma|High Grade Serous Carcinoma|Peritoneal Carcinoma|Peritoneal Neoplasms|Adnexal Mass|Ovarian Diseases
Interventions: DEVICE: Hysteroscopic cell sampling of the fallopian tube
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of a Theory-Driven Manualized Approach to Improving New Learning and Memory in MS
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Strategy-Based Training to Enhance Memory (STEM)|BEHAVIORAL: Placebo control exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for Parkinson's Disease Using Allogeneic HB-adMSCs (Early and Moderate PD)
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: BIOLOGICAL: Biological/Vaccine: Allogeneic HB-adMSCs|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation in Patients With Diabetes Mellitus Type 2
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2|Vitamin D Deficiency
Interventions: DRUG: Vitamin D supplementation|DRUG: Placebo Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Pharmacist-led Educational Intervention on Pneumococcal Vaccination Rates in Cancer Patients
Status: COMPLETED
Conditions: Pneumonia, Bacterial|Cancer|Pneumococcal Infections
Interventions: BEHAVIORAL: vaccine education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Fever After Simultaneous Versus Sequential Vaccination in Young Children
Status: COMPLETED
Conditions: Fever After Vaccination|Fever|Febrile Seizure
Interventions: BIOLOGICAL: PCV13|BIOLOGICAL: DTaP|BIOLOGICAL: IIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study Comparing Efficacy of Levodopa-Carbidopa Intestinal Gel/Carbidopa-Levodopa Enteral Suspension and Optimized Medical Treatment on Dyskinesia in Subjects With Advanced Parkinson's Disease (DYSCOVER)
Status: COMPLETED
Conditions: Parkinson's Disease (PD)
Interventions: DRUG: Optimized antiparkinsonian treatment|DRUG: Levodopa-Carbidopa Intestinal Gel (LCIG)|DEVICE: CADD-Legacy ambulatory infusion pump|DEVICE: Percutaneous endoscopic gastrostomy tube|DEVICE: Jejunal extension tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testosterone Administration and ACL Reconstruction in Men
Status: COMPLETED
Conditions: Muscle Atrophy|ACL Reconstruction|Trauma|Osteoarthritis
Interventions: DRUG: Testosterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of LCZ696 on Urinary Microalbumin and Pulse Wave Velocity in Perimenopausal Patients With Hypertension
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: Sacubitril/Valsartan|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Planning and Cognitive Behavioral Therapy for Adolescent Suicide Prevention in Mozambique
Status: NOT_YET_RECRUITING
Conditions: Suicide Prevention
Interventions: BEHAVIORAL: Safety Planning Intervention|BEHAVIORAL: Enhanced Usual Care|BEHAVIORAL: Transdiagnostic Cognitive Behavioral Therapy for Suicide Prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIV, Equity, and Addiction Training (HEAT) Program
Status: NOT_YET_RECRUITING
Conditions: Substance Use Disorders|Hiv|Opioid Use Disorder|Stimulant Use (Diagnosis)
Interventions: OTHER: Telemedicine|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The HistoSonics System for Treatment of Primary and Metastatic Liver Tumors Using Histotripsy (#HOPE4LIVER EU/UK)
Status: ACTIVE_NOT_RECRUITING
Conditions: Liver Neoplasms|Hepatocellular Carcinoma|Liver Metastases
Interventions: DEVICE: HistoSonics System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Value of Using a Honey Dressing Compared to the Use of a Standard Dressing on the Toe Amputation Wound in the Diabetic Patient
Status: COMPLETED
Conditions: Diabete Mellitus|Amputation|Amputation Wound|Toe (Toes); Wound
Interventions: DEVICE: Honey dressing Melectis G|DEVICE: HAS recommendation dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Cap-assisted Water Exchange and Water Exchange in Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy|Intubation Time|Cap-assisted Colonoscopy
Interventions: DEVICE: cap-assisted water exchange|PROCEDURE: water exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessing the Integration of Tobacco Cessation Treatment Into Lung Cancer Screening (LCS)
Status: COMPLETED
Conditions: Smoking, Tobacco
Interventions: BEHAVIORAL: Counseling|DRUG: Nicotine patch|BEHAVIORAL: Community Resource
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of HSC835 in Patients With Hematological Malignancies
Status: COMPLETED
Conditions: Acute Myelocytic Leukemia|Acute Lymphocytic Leukemia|Chronic Myelogenous Leukemia|Myelodysplastic Syndrome|Chronic Lymphocytic Leukemia|Marginal Zone Lymphoma|Follicular Lymphomas|Large-cell Lymphoma|Lymphoblastic Lymphoma|Burkitt's Lymphoma|High Grade Lymphomas|Mantle-cell Lymphoma|Lymphoplasmacytic Lymphoma
Interventions: BIOLOGICAL: HSC835
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study Comparing the Inflammatory Response of the Ex-Press Mini Shunt to Trabeculectomy
Status: TERMINATED
Conditions: Glaucoma
Interventions: PROCEDURE: Trabeculectomy with mitomycin c|PROCEDURE: Ex-Press mini shunt with mitomycin c
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel
Status: COMPLETED
Conditions: Acute Ischemic Stroke|Transient Ischemic Attack (TIA)
Interventions: DRUG: BMS-986177|OTHER: Placebo|DRUG: Clopidogrel|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PGL2001 Proof of Concept Study in Symptomatic Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: PGL2001 + Primolut-Nor 5|DRUG: Placebo + Primolut-Nor 5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Heat Therapy, Functional Capacity, and Vascular Health in Older Adults
Status: RECRUITING
Conditions: Aging Well|Walking, Difficulty|Hyperemia
Interventions: OTHER: Home-based leg heat therapy|OTHER: Home-based sham therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tranexamic Acid in Revision Total Joint Arthroplasty
Status: COMPLETED
Conditions: Revision Total Knee Arthroplasty|Revision Total Hip Arthroplasty|Acute Blood Loss Anemia
Interventions: PROCEDURE: Revision Total Knee Arthroplasty (TKA)|PROCEDURE: Revision Total Hip Arthroplasty (THA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Strengthening Exercises Versus Proprioception and Balance Exercises in the Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteo Arthritis Knee|Pain
Interventions: OTHER: Proprioception and Balance Program|OTHER: Strengthening Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Immunological and Clinical Efficacy of Multiple Subcutaneous Doses of DiaPep277 in Latent Autoimmune Diabetes in Adults (LADA)
Status: TERMINATED
Conditions: Diabetes, Autoimmune
Interventions: DRUG: DiaPep277
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT