pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Subcutaneous ALXN1830 in Adult Participants With Warm Autoimmune Hemolytic Anemia
Status: WITHDRAWN
Conditions: Warm Autoimmune Hemolytic Anemia
Interventions: DRUG: ALXN1830|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Content of Barley Beta-glucans in Bread on Postprandial Blood Sugar
Status: COMPLETED
Conditions: Glycemic Index
Interventions: OTHER: REFERENCE: white bread - BGL0 [RP]|OTHER: TEST: b-glucan enriched bread - BGL2 [IP1]|OTHER: TEST: b-glucan enriched bread - BGL3 [IP2]|OTHER: TEST: b-glucan enriched bread - BGL4 [IP3]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Fluzoparib in Combination With mFOLFIRINOX in Patients With Resectable Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: Fluzoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of the Combination of Anlotinib With Pemetrexed or Docetaxel
Status: UNKNOWN
Conditions: Non-squamous Non-small Cell Lung Cancer
Interventions: DRUG: Anlotinib|DRUG: Pemetrexed|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Photodamaged Skin of the décolleté
Status: TERMINATED
Conditions: Photodamaged Skin
Interventions: COMBINATION_PRODUCT: Photodynamic therapy|DEVICE: Non-ablative Thulium laser (NAFL)|DEVICE: Radio-frequency microneedles (RF-MN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Cannabis Use and Depression in Everyday Moments Among Youth (ACADEMY)
Status: NOT_YET_RECRUITING
Conditions: Cannabis Use|Depression|Suicidal Ideation|Adolescent Behavior
Interventions: BEHAVIORAL: Contingency management for cannabis abstinence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rapid SARS-CoV-2 IgG Antibody Testing in High Risk Healthcare Workers
Status: COMPLETED
Conditions: SARS-CoV-2
Interventions: DIAGNOSTIC_TEST: SARS-CoV-2 IgG Antibody Testing Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy
Status: COMPLETED
Conditions: Brain Tumor|Central Nervous System Tumor|Childhood Germ Cell Tumor|Extragonadal Germ Cell Tumor|Liver Cancer|Neuroblastoma|Ototoxicity|Ovarian Cancer|Sarcoma
Interventions: DRUG: sodium thiosulfate|PROCEDURE: examination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Efficacy of Flexible Ureteroscope and Percutaneous Nephroscopic Surgery in the Treatment of 2-4cm Kidney Stones
Status: RECRUITING
Conditions: Kidney Stone
Interventions: PROCEDURE: flexible ureteroscopic lithotripsy|PROCEDURE: percutaneous nephrolithotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Bisacodyl Sugar Coated Tablets, Simeticone Chewing Tablets and Their Combination in Constipation and Bloatedness
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Bisacodyl|DRUG: Simeticone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An fMRI Study of SYN115 in Cocaine Dependent Subjects
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: SYN115|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Synergy Trial: Methylphenidate Plus a CFS-Specific Nutrient Formula as a Treatment for Chronic Fatigue Syndrome
Status: UNKNOWN
Conditions: Chronic Fatigue Syndrome (CFS)|Myalgic Encephalomyelitis (ME)
Interventions: DRUG: Methyl-P plus Nutrient Formula|DRUG: Methyl-P plus Nutrient matched placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Observer Blinded Comparison of MACE and Conventional Upper Gastrointestinal Endoscopy in Upper GI Bleeding
Status: COMPLETED
Conditions: Gastrointestinal Diseases
Interventions: DEVICE: Magnetic Assisted Capsule Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lesion Detection of Automated Breast Ultrasound Compared With Handheld Physician-performed Breast Ultrasound
Status: COMPLETED
Conditions: Breast Diseases
Interventions: DEVICE: Supine automated breast ultrasound scanner|DEVICE: High-resolution handheld breast ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Core Strength Training Using Stable Versus Unstable Surfaces
Status: COMPLETED
Conditions: Sports Physical Therapy
Interventions: OTHER: Core strength training using unstable surface|OTHER: The stable surface would be gym floor.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study of Lurbinectedin With Radiotherapy in Locally-advanced SCLC After First-line Therapy
Status: NOT_YET_RECRUITING
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: Lurbinectedin|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Versus Intermittent Ward Monitoring
Status: WITHDRAWN
Conditions: Surgery
Interventions: DEVICE: Blinded continuous vital sign monitoring|DEVICE: Unblinded continuous vital sign monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ph II Cilengitide Plus Bevacizumab for Recurrent Glioblastoma (GBM)
Status: WITHDRAWN
Conditions: Glioblastoma
Interventions: DRUG: Cilengitide|DRUG: Bevacizumab|BEHAVIORAL: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Primary Fascial Closure Rate in Patients With Open Abdomen Treated With Abthera Versus Barker Technique
Status: UNKNOWN
Conditions: Abdominal Trauma|Abdominal Sepsis|Abdominal Compartment Syndrome
Interventions: DEVICE: Abthera|DEVICE: Barker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Fu's Subcutaneous Needling for Patients With Chronic Neck Pain
Status: UNKNOWN
Conditions: Chronic Neck Pain|Sleep Quality
Interventions: PROCEDURE: Fu's subcutaneous needling|PROCEDURE: Transcutaneous electrical nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Bioavailability Study of Eplerenone 50 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Eplerenone 50 mg Tablets Sandoz Inc., USA|DRUG: Inspra 50 mg Tablets GD Searle LLC, USA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: De-escalating Antiplatelet Therapy to Assess Platelet Reactivity and Outcomes in High Bleeding Risk Patients With Recent ACS
Status: RECRUITING
Conditions: Dual Antiplatelet Therapy|Acute Coronary Syndrome|Coronary Artery Disease
Interventions: DRUG: P2Y12 inhibitor de-escalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Oxalate and Immune Cell Function
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Stone
Interventions: DIETARY_SUPPLEMENT: Breakfast|DIETARY_SUPPLEMENT: Spinach smoothie|DIETARY_SUPPLEMENT: Kale smoothie|DIETARY_SUPPLEMENT: Blended smoothie|DIETARY_SUPPLEMENT: V spinach smoothie|DIETARY_SUPPLEMENT: Sodium oxalate drink
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pragmatic Cluster Trial of a Tailored Intervention to Improve COPD Management
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: OTHER: Implementation educational programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dose-ranging Study: Safety, Tolerability and Immunogenicity of INO-4500 in Healthy Volunteers in Ghana
Status: COMPLETED
Conditions: Lassa Fever
Interventions: DRUG: INO-4500|DEVICE: CELLECTRA™ 2000|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Open Label, Clinical Trial of the Pharmacokinetics of Azithromycin Following a Single Dose of Azithromycin Sustained Release (2 Gram) or Commercial Azithromycin Tablet (500 mg) to Cancer Patients That Require Lung Surgery
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: azithromycin immediate release (Zithromax)|OTHER: placebo|DRUG: azithromycin SR|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of Hemopatch as a Sealant at the Pancreaticojejunostomy After Pancreatoduodenectomy
Status: COMPLETED
Conditions: Pancreatic Fistula
Interventions: DEVICE: Hemopatch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Clinical Trial of Re-Evaluating Suicidal Thoughts in Veterans
Status: RECRUITING
Conditions: Suicidal Ideation|Suicide, Attempted
Interventions: OTHER: Treatment-as-usual|BEHAVIORAL: Re-Evaluating Suicidal Thoughts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of the Water Jet Device in Removing Dental Plaque Around Orthodontic Braces in Adolescents
Status: COMPLETED
Conditions: Plaque, Dental
Interventions: DEVICE: Water Jet|DEVICE: Manual toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Developing an Utstein-style Danish Drowning Registry: Nationwide Fatal and Nonfatal Drowning Data Since 2016
Status: NOT_YET_RECRUITING
Conditions: Drowning|Drowning, Near|Drowning; Asphyxia|Drowning and Nonfatal Submersion|Drowning or Immersion of Unknown Intent|Drowning and Submersion, Undetermined Intent|Drowning and Submersion While in Bath-Tub|Drowning and Submersion While in Natural Water|Drowning and Submersion While in Swimming-Pool
Interventions: OTHER: Drowning
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Single Dose Trial in Healthy Caucasians and Japanese Subjects Investigating the Pharmacokinetics of Somatropin
Status: COMPLETED
Conditions: Growth Hormone Disorder|Adult Growth Hormone Deficiency|Healthy
Interventions: DRUG: somatropin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Type I Hepatorenal Syndrome (HRS) With Pentoxyfylline
Status: TERMINATED
Conditions: Hepatorenal Syndrome
Interventions: DRUG: Pentoxyfylline|DRUG: Placebo|DRUG: AMO Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Optimal Treatment for Treatment-resistant Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Risperidone with Clozapine|DRUG: Aripiprazole with Clozapine|DRUG: sodium valproate with Clozapine|DEVICE: modified electroconvulsive therapy(MECT) with Clozapine|DEVICE: Magnetic seizure therapy(MST) with Clozapine|DEVICE: clozapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Graded Exposure (GEXP) in Vivo Versus Physiotherapy in Complex Regional Pain Syndrome Type I (CRPS-I)
Status: COMPLETED
Conditions: Complex Regional Pain Syndrome Type I
Interventions: BEHAVIORAL: Graded exposure in vivo|BEHAVIORAL: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-Osteoclast Therapy as Neoadjuvant in Treatment of Chondrosarcoma - Phase 1b Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Chondrosarcoma
Interventions: DRUG: Zoledronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Clinical Study on the Safety and Effectiveness of CAR-T in the Treatment of Relapsed/Refractory Plasma Cell Tumors
Status: RECRUITING
Conditions: Plasma Cell Tumors
Interventions: BIOLOGICAL: Auto CAR-T|DRUG: Cyclophosphamide,Fludarabine|PROCEDURE: Leukapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of SM on Postural Instability and Quality of Life in Patients With Chronic Non Specific Low Back Pain(CNSLBP)
Status: COMPLETED
Conditions: Chronic Non Specific Low Back Pain
Interventions: OTHER: Spinal Manipulation|OTHER: Exercise therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Adding Pilates to Postural Correction Exercise on Nerve Root Function and Electromyography Activity in Symptomatic Forward Head Posture: Randomized Controlled Trial
Status: COMPLETED
Conditions: Forward Head Posture
Interventions: OTHER: Pilates and postural correction exercise|OTHER: Pilates exercises|OTHER: postural correction exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Probiotic Composition as Adjunct in MAFL Management
Status: COMPLETED
Conditions: Non Alcoholic Fatty Liver
Interventions: DIETARY_SUPPLEMENT: Probiotic composition|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tracking Response to Antidepressants in Advance of Investigational Trials
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: FDA-approved selective-serotonin reuptake inhibitors (SSRIs) and selective-norepinephrine reuptake inhibitors (SNRIs)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BrUOG 354 Nivolumab +/- Ipilimumab for Ovarian and Extra-renal Clear Cell Carcinomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma|Extra Renal Origin|Clear Cell Adenocarcinoma
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Natural Dendritic Cells for Immunotherapy of Chemo-naive Metastatic Castration-resistant Prostate Cancer Patients
Status: COMPLETED
Conditions: Prostatic Neoplasms|Immunotherapy|Dendritic Cells|Vaccines
Interventions: BIOLOGICAL: mDC vaccination|BIOLOGICAL: pDC vaccination|BIOLOGICAL: mDC and pDC vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Bi-26 Supplementation on Weight Gain in Underweight Infants
Status: TERMINATED
Conditions: Underweight|Paediatrics
Interventions: DIETARY_SUPPLEMENT: B. infantis Bi-26|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Patient Navigation in the Adolescent and Young Adult (AYA) Cancer Population
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: Patient Navigator (PN)|OTHER: Baseline Questionnaire|OTHER: Follow-up Questionnaire|OTHER: Patient Navigator Satisfaction Survey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Supported Employment: Motivational Enhancement for Entry and Outcome
Status: COMPLETED
Conditions: Psychotic Disorders|Bipolar Disorder|Unemployment
Interventions: BEHAVIORAL: Adapted Motivational Interviewing (AMI)|BEHAVIORAL: Support and Education for Recovery (SER)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Role of Herbal Dentifrices in the Management of Plaque Induced Gingivitis
Status: COMPLETED
Conditions: Gingiva; Infection|Plaque, Dental
Interventions: OTHER: dentifrice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Pilot Evaluation of 124I-Iodo-Azomycin Galacto-Pyranoside (*IAZGP) Positron Emission Tomography (PET) in the Imaging of Hypoxic Tumors
Status: COMPLETED
Conditions: Cervical Cancer|HEENT Cancer|Renal Cancer|Uterine Cancer|CERVIX UTERI NOS|RECTUM
Interventions: RADIATION: 124I-Iodo-Azomycin Galacto-Pyranoside
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Of VGX-3400, H5N1 Avian Flu Virus Plasmid DNA With Electroporation Device In Healthy Adult Males
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: VGX-3400
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Intervention to Reduce Inappropriate Medications in Long-term Care Residents With Severe Dementia
Status: COMPLETED
Conditions: Dementia|Inappropriate Prescribing
Interventions: BEHAVIORAL: Knowledge exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Prospective Double-blind Interventional Study of Tissue Reaction to Polyglycolic Acid Sutures in Human Skin
Status: COMPLETED
Conditions: Lower Eyelid Entropion
Interventions: PROCEDURE: 7/0 vicryl suture|PROCEDURE: 5/0 vicryl test suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Compression in Anklefracture Treatment, The CAT-study
Status: UNKNOWN
Conditions: Ankle Fractures
Interventions: DEVICE: Flowtron Hydroven and Coban2 Lite|OTHER: Braun frame|DEVICE: compression bandage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dietary Calcium Supplementation, Gut Permeability and Microbiota in Type 2 Diabetics
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Overweight
Interventions: DIETARY_SUPPLEMENT: Dietary calcium supplementation|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Unloader One Study on Knee Osteoarthritis Hässleholm Sweden
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Unloader One brace|DEVICE: Placebo brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Injection of Oncolytic Viruses H101 for Patients With Refractory Malignant Ascites
Status: COMPLETED
Conditions: Refractory Malignant Ascites
Interventions: DRUG: Oncorine (H101)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of 4-AP on Functional SCI Recovery
Status: RECRUITING
Conditions: Spinal Cord Injury
Interventions: DRUG: Dalfampridine|OTHER: Placebo drug|OTHER: STDP stimulation|BEHAVIORAL: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wait-list Study of One-Week Intensive Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder (OCD)
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: BEHAVIORAL: 5-day intensive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Trial Evaluating Radium Bromatum Homeopathic Treatment Efficacy on Radiodermatitis Prevention and Treatment for Breast Cancer Women
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Placebo pills of Radium bromatum|DRUG: Radium bromatum pills|DRUG: Radium bromatum/Apis mellifica/Belladonna placebo pills|DRUG: Radium bromatum/Apis mellifica/Belladonna pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Analysis Between Bipolar Device and Conventional Tie & Suture Technique in Thyroidectomy
Status: UNKNOWN
Conditions: Thyroid Goiter|Papillary Thyroid Cancer
Interventions: DEVICE: Bipolar vessel sealing and cutting device|PROCEDURE: Conventional thyroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study to Evaluate the Effect of a Nu Skin Product and Device for Brown Spots
Status: COMPLETED
Conditions: Hyperpigmentation
Interventions: OTHER: Nu Skin Product|OTHER: Cosmetic instrument|DRUG: Tretinoin cream 0.05|OTHER: CeraVe moisturizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neurofunctional Correlates of the Behavioral Modifications Associated With Tachidino in Children With Developmental Dyslexia
Status: UNKNOWN
Conditions: Dyslexia, Developmental
Interventions: BEHAVIORAL: TACHIDINO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of LLG783 in Patients With Peripheral Artery Disease (PAD) and Intermittent Claudication
Status: COMPLETED
Conditions: Peripheral Artery Disease (PAD); Intermittent Claudication
Interventions: DRUG: LLG783|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Open-label Study to Assess the Safety of Oral Long-term Use of SA-001 in Pancreatic Exocrine Insufficiency
Status: COMPLETED
Conditions: Pancreatic Exocrine Insufficiency, Chronic Pancreatitis, Pancreatectomy
Interventions: DRUG: SA-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Second-line FOLFIRI + Panitumumab in Subjects With Wild Type RAS Metastatic Colorectal
Status: UNKNOWN
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Panitumumab|DRUG: Irinotecan|DRUG: Folinic acid|DRUG: 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetic Profiles and Safety of CKD-393(2) in Healthy Volunteers Under Fed Conditions
Status: COMPLETED
Conditions: Type2Diabetes
Interventions: DRUG: CKD-393(2)|DRUG: CKD-501, D759, D150, D029
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic HBV Infection in Pregnant Women Taking TAF to Prevent Vertical Transmission
Status: UNKNOWN
Conditions: Hepatitis B, Chronic|Pregnancy Related
Interventions: DRUG: Tenofovir Alafenamide 25 MG|DRUG: Tenofovir Disoproxil Fumarate 300 MG Oral Tablet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of CBD Oil on Memory Reconsolidation and Trauma-Related Symptoms
Status: WITHDRAWN
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Trauma Memory Reactivation|DIETARY_SUPPLEMENT: Cannabidiol (CBD) Broad-Spectrum Oil|DIETARY_SUPPLEMENT: Placebo Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modifications in the Eating Habits of Adolescents of Secondary Education as a Result of a Nutritional Intervention
Status: COMPLETED
Conditions: Food Habits
Interventions: BEHAVIORAL: Nutritional intervention based on the SCT and the TM|BEHAVIORAL: Nutritional information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lipoic Acid as a Treatment for Acute Optic Neuritis
Status: COMPLETED
Conditions: Optic Neuritis
Interventions: DRUG: Lipoic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S0430 Cyclophosphamide and Capecitabine in Treating Women With Stage IV Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: capecitabine|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digitalis Investigation Group (DIG)
Status: COMPLETED
Conditions: Arrhythmia|Cardiovascular Diseases|Heart Diseases|Heart Failure, Congestive|Sinus Arrhythmia|Heart Failure
Interventions: DRUG: digitalis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Spastic Paraplegia - Centers of Excellence Research Network
Status: RECRUITING
Conditions: Hereditary Spastic Paraplegia|Primary Lateral Sclerosis|SPG4|SPG5A|Spastic Paraplegia 4|Spastic Paraplegia 5A|Early Onset Hereditary Spastic Paraplegia|Neuromuscular Diseases|Spastic Paraplegia, Hereditary
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness Between Two Surgical Techniques for Reconstruction of Humeral Proximal Extremity Fractures
Status: COMPLETED
Conditions: A02.835.232.087.090.400.400
Interventions: PROCEDURE: Hemiarthroplasty|PROCEDURE: reverse arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ursodeoxycholic Acid (UDCA) for Hepatic Sarcoidosis
Status: TERMINATED
Conditions: Hepatic Sarcoidosis, Elevated Alkaline Phosphatase
Interventions: DRUG: Ursodeoxycholic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sumatriptan and Placebo on Cilostazol Induced Headache
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Cilostazol|DRUG: Sumatriptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Paclitaxel (Albumin-bound) Combined With Cisplatin, PD-1 Inhibitors and IMRT in the Treatment of Nasopharyngeal Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: COMBINATION_PRODUCT: Paclitaxel（Albumin-bound）
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Immune Response and Safety Elicited by a Vaccine Against Respiratory Syncytial Virus (RSV) When Given Alone and Together With a Vaccine Against Influenza in Adults Aged 65 Years and Above
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSVPreF3 OA investigational vaccine|BIOLOGICAL: FLU HD vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: T Cell Membrane-Anchored Tumor-Targeted IL12 -Modified TIL Cell Therapy (attIL12-TIL) for Advanced/Metastatic Soft Tissue and Bone Sarcoma Patients.
Status: NOT_YET_RECRUITING
Conditions: Metastatic Soft-tissue Sarcoma
Interventions: DRUG: Cyclophosphamide|DRUG: T Cell Membrane-Anchored Tumor-Targeted IL12 -Modified TIL Cell Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of JMT103 in Patients With Giant Cell Tumor of Bone
Status: ACTIVE_NOT_RECRUITING
Conditions: Giant Cell Tumor of Bone
Interventions: DIETARY_SUPPLEMENT: Dietary Supplement: Calcium/Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Hormone Replacement Therapy on Arthralgia in Postmenopausal Women
Status: UNKNOWN
Conditions: Arthralgia
Interventions: DRUG: Conjugated Equine Estrogen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ADH 1 in Combination With Carboplatin, or Docetaxel or Capecitabine
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: ADH -1 and carboplatin|DRUG: ADH -1 and docetaxel|DRUG: ADH -1 and capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expectations and Pain Control Advancement In surgeRy: The REPAIR Trial
Status: COMPLETED
Conditions: Abuses Over-The-Counter/Prescription Medications|Pain, Postoperative|Opioid Use|Physical Activity|Patient Dependence on
Interventions: BEHAVIORAL: Patient centered pre-op education|BEHAVIORAL: routine preop education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Empagliflozin (BI 10773) / Linagliptin (BI 1356) Fixed Dose Combination in Treatment naïve and Metformin Treated Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: high dose FDC|DRUG: BI 10773 high dose|DRUG: high dose FDC placebo|DRUG: low dose FDC placebo|DRUG: high dose FDC placebo|DRUG: high dose FDC placebo|DRUG: low dose FDC placebo|DRUG: low dose FDC placebo|DRUG: high dose BI 10773 placebo|DRUG: low dose FDC|DRUG: high dose FDC placebo|DRUG: BI 10773 low dose|DRUG: high dose BI 10773 placebo|DRUG: high dose BI 10773 placebo|DRUG: linagliptin|DRUG: low dose FDC placebo|DRUG: linagliptin placebo|DRUG: BI 10773 low dose placebo|DRUG: linagliptin placebo|DRUG: low dose BI 10773 placebo|DRUG: linagliptin placebo|DRUG: high dose BI 10773 placebo|DRUG: BI 10773 low dose placebo|DRUG: low dose BI 10773 placebo|DRUG: linagliptin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Futility Trial of Sirolimus in Multiple System Atrophy
Status: TERMINATED
Conditions: Multiple System Atrophy
Interventions: DRUG: Sirolimus 2 MG|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effects of Supplemental Vitamin C on Infant Lung Function in Pregnant Smoking Women
Status: COMPLETED
Conditions: Pregnancy|Smoking
Interventions: OTHER: Placebo|DIETARY_SUPPLEMENT: Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Perioperative Dexamethasone Reduces Postoperative Pain and Nausea After Periacetabular Osteotomy
Status: RECRUITING
Conditions: Pain|Postoperative Nausea|Amount of Postoperative Opioid Use in Milligrams
Interventions: DRUG: Dexamethasone 4 Mg/mL Injectable Solution|DRUG: NaCl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Open-Label Study to Assess the Single-Dose Pharmacokinetics of Eravacycline in Subjects With End Stage Renal Disease and Healthy Subjects
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DRUG: eravacycline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antidepressant Effects of NR2B in Major Depression
Status: COMPLETED
Conditions: Major Depression
Interventions: DRUG: MK-0657|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Tolerability and Adherence of the Modified Atkins Diet on Drug-resistant Epilepsy
Status: COMPLETED
Conditions: Epilepsy, Drug Resistant
Interventions: OTHER: modified adkins diet|DRUG: Pharmacotherapy without diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nasogastric Tube Securement Comparison Study
Status: COMPLETED
Conditions: Failure to Thrive|Nutritional Deficiency|Constipation|Bowel Obstruction|Feeding and Eating Disorders
Interventions: DEVICE: Nasal Bridle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Neutrophil/Lymphocyte Ratio ,Platelet/Lymphocyte Ratio and CRP as Markers of Severity of Pre-eclampsia
Status: UNKNOWN
Conditions: Pre-Eclampsia
Interventions: DIAGNOSTIC_TEST: Neutrophil/lymphocyte ratio, Platelet /lymphocyte ratio and CRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Extension Study of UC-961 (Cirmtuzumab) for Patients With Chronic Lymphocytic Leukemia Treated Previously With UC-961
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: cirmtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulation of Mucosal and Systemic Immunity by Hormonal Contraceptives
Status: TERMINATED
Conditions: Initiation of Oral Contraception (OC)|Initiation of Depo-Provera (DMPA)|Initiation of Mirena (LNG-IUD)
Interventions: DRUG: Mirena|DRUG: Oral contraception|DRUG: Depo-Provera
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intervention to Change Attributions That Are Negative (ICAN)
Status: COMPLETED
Conditions: Trauma, Brain|Brain Injuries|Traumatic Brain Injury|Brain Injuries, Traumatic|Brain, Trauma
Interventions: BEHAVIORAL: ICAN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of QMF149 vs. Salmeterol Xinafoate/Fluticasone Propionate in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: QMF149|DRUG: Salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic Walking for Children Who Cannot Walk
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Palsy|Mobility Limitation|Brain Injuries|Spinal Cord Injuries|Spina Bifida
Interventions: DEVICE: Robotic Training Period
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare Effect of Sevoflurane Versus Desflurane on the Return of Swallowing Reflexes in the Elderly
Status: COMPLETED
Conditions: Pulmonary Aspiration
Interventions: DRUG: Sevoflurane|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Simplified Antiviral Treatment Strategy for Hepatitis C in Myanmar
Status: COMPLETED
Conditions: Hepatitis C|Hepatitis B|HIV Infections
Interventions: DRUG: sofosbuvir 400 mg/velpatasvir 100 mg (SOF/VEL) orally once daily for 12 weeks with or without weight-based ribavirin.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Efficacy and Safety of Oral Administration With Nemonoxacin and Levofloxacin in Patients With CAP
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Levofloxacin|DRUG: Nemonoxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MRI and Microbiota Analysis in Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DIETARY_SUPPLEMENT: Ispaghula|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Novel Interventions in HIV-1 Infection
Status: TERMINATED
Conditions: HIV-1 Infection
Interventions: BIOLOGICAL: GTU-MultiHIV B clade vaccine1mg|DRUG: Interleukin-2|DRUG: GM-CSF|DRUG: Growth Hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Finding Study to Evaluate the Efficacy and Safety of Modafinil as Treatment for Adults With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|ADHD
Interventions: DRUG: Modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Between Colchicine and Calcineurin Inhibitors in Renal Graft Recipients
Status: COMPLETED
Conditions: Renal Replacement Therapies
Interventions: DRUG: cyclosporine+colchicine|DRUG: tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ligament Balancing in Total Knee Arthroplasty
Status: NOT_YET_RECRUITING
Conditions: Ligament; Laxity, Knee|Knee Osteoarthritis
Interventions: DEVICE: A novel instrument for ligament balancing in total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calcaneal Osteotomy for Intractable Plantar Fasciitis
Status: NOT_YET_RECRUITING
Conditions: Plantar Fascitis
Interventions: PROCEDURE: calcaneal osteotomy for intractable plantar fasciitis|PROCEDURE: plantar fascia open release|PROCEDURE: plantar fascia endoscopic release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcranial Direct Current Electrical Stimulation on the Recovery of Ideomotor Apraxia of the Upper Limbs
Status: RECRUITING
Conditions: Apraxia, Ideomotor
Interventions: DEVICE: transcranial Direct Current Stimulation (tDCS)|DEVICE: Sham stimulation (sham-tDCS)|DEVICE: Behavioural
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vascular Reactivity in Chronic Kidney Disease (CKD) Patients Receiving Paricalcitol Versus Placebo
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Paricalcitol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: A Novel Probiotic-antibiotic Combination to Prevent Recurrent Urinary Tract Infections
Status: RECRUITING
Conditions: Recurrent Uti
Interventions: DRUG: Saccharomyces Boulardii 250 MG [Florastor]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Daily Light and Sound Stimulation to Improve Brain Functions in Alzheimer's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease|Alzheimer Dementia
Interventions: DEVICE: GENUS device (Active Settings)|DEVICE: GENUS device (Sham Settings)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of GFH375 in Patients With Advanced Solid Tumors With KRAS G12D Mutations
Status: RECRUITING
Conditions: KRAS G12D Mutations|Advanced Solid Tumors
Interventions: DRUG: GFH375
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Cardiac Resynchronization Therapy on Right Ventricular Function in Left Ventricular Assist Device Patients
Status: WITHDRAWN
Conditions: Heart Failure
Interventions: DEVICE: Cardiac Resynchronization Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19 ThromboprophylaXIs Study of Novel FXIa Inhibitor Frunexian (EP-7041) in ICU Patients
Status: WITHDRAWN
Conditions: Thrombopenia|Covid19
Interventions: DRUG: EP-7041 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pragmatic Trial of Two Strategies for Implementing an Effective eHealth HIV Prevention Program (Keep It Up! 3.0)
Status: COMPLETED
Conditions: HIV/AIDS|Gonorrhea|Chlamydia
Interventions: BEHAVIORAL: Keep It Up! 3.0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Predictive Value of Blood Levels of Angiopoietin 1 and Endothelial Internal Tunica Cell Kinase 2 in Patients With Ovarian Cancer Treated With Chemotherapy Associated to Bevacizumab
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: OTHER: Observational study. Blood samples will be collected at scheduled blood draws performed as per clinical practice before each cycle of chemotherapy.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact and Cost-effectiveness of Safer Conception Strategies for HIV-discordant Couples (SAFER)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: PrEP (Truvada)|DRUG: Antiretrovirals|PROCEDURE: Semen washing|PROCEDURE: Artificial vaginal insemination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ventralex vs Stratafix for Primary Ventral Hernias
Status: RECRUITING
Conditions: Ventral Hernia
Interventions: DEVICE: Ventralex|OTHER: Stratafix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn More About How Safe Darolutamide is and How Well it Works Under Real World Conditions When Taken in Addition to Standard Androgen Deprivation Therapy (ADT) in Indian Participants With High-risk Non-metastatic Castration-resistant Prostate Cancer (nmCRPC)
Status: RECRUITING
Conditions: Non-metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Darolutamide (Nubeqa, BAY1841788)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Myocardial Improvement in Patients Supported by Ventricular Assist Device Under Optimal Pharmacological Therapy
Status: TERMINATED
Conditions: Heart Failure
Interventions: DRUG: Pravastatin, Carvedilol, Perindopril|DEVICE: Biventricular assist device (Thoratec paracorporeal assist device)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Thalidomide in Treating Patients Who Have Undergone Surgery and Chemotherapy for Cancer That Has Spread Throughout the Abdomen Due to Colorectal Cancer or Appendix Cancer
Status: COMPLETED
Conditions: Carcinoma of the Appendix|Colorectal Cancer
Interventions: DRUG: thalidomide|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT