pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Neuroprotective Effects of Risperdal on Brain and Cognition in 22q11 Deletion Syndrome
Status: TERMINATED
Conditions: 22q11.2 Deletion Syndrome
Interventions: DRUG: Risperdal|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Impact of Estradiol on Endothelial Function in Peri-Menopausal Women
Status: RECRUITING
Conditions: Perimenopause|Vasodilation|Estrogen
Interventions: DRUG: Estradiol (mylan or vivelle dot patch)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sleep and Immune Response in Severe Obese Patients Undergoing Bariatric Surgery.
Status: UNKNOWN
Conditions: Severe Obesity|Morbid Obesity
Interventions: PROCEDURE: Standard Roux-en-Y gastric bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Translational Tissue Collection Study in Early and Advanced Pancreatic Ductal Adenocarcinoma and Pancreatic Neuroendocrine Tumours to Enable Further Disease Characterisation and the Development of Potential Predictive and Prognostic Biomarkers
Status: UNKNOWN
Conditions: Pancreatic Adenocarcinoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Menstrual Cycle on Antiretroviral Pharmacokinetics in Healthy Women
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: tenofovir|DRUG: emtricitabine|DRUG: atazanavir|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Remote Ischemic Preconditioning on Electrophysiological and Biomolecular Parameters in Non-valvular Paroxysmal Atrial Fibrillation: RIPPAF Study
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Remote ischemic preconditioning (RIPC)|PROCEDURE: sham-intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Instrument Assisted Soft Tissue Mobilization Versus Trigger Points Release on Upper Trapezius Trigger Points
Status: COMPLETED
Conditions: Trigger Points
Interventions: OTHER: Soft tissue release technique|OTHER: Comparator: Instrument assisted soft tissue mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Thermo-mechanical System for Fractional Ablation Associated Triamcinolone Acetonide Drug Delivery for the Treatment of Hypertrophic Scars and Keloids
Status: UNKNOWN
Conditions: Keloid
Interventions: DEVICE: Thermomechanical system with corticosteroids|OTHER: corticosteroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transdiagnostic, Indicated Preventive Intervention for Adolescents At High Risk of Emotional Problems W/Add-On Modules
Status: RECRUITING
Conditions: Anxiety Disorders and Symptoms|Depressive Symptoms
Interventions: BEHAVIORAL: Active control condition|BEHAVIORAL: PROCARE-I+ 8-session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability Study of E-WE Thrombin in Healthy Adult Subjects
Status: COMPLETED
Conditions: Thrombosis
Interventions: DRUG: E-WE Thrombin- Dose 1|DRUG: E-WE Thrombin- Dose 2|DRUG: E-WE Thrombin- Dose 3|DRUG: E-WE Thrombin- Dose 4|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intraperitoneal Injection of Magnesium Sulphate Versus Dexmedetomidine as an Adjuvant to Bupivacaine on Postoperative Analgesia in Patients Undergoing Abdominal Aortic Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Abdominal Aortic Surgery
Interventions: DRUG: magnesuim sulphate|DRUG: Dexmedetomidine|DRUG: isobaric bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Behavioral Sleep Intervention in Children With Disruptive Behaviors
Status: COMPLETED
Conditions: Insomnia|Disruptive Behavior Disorder|Oppositional Defiant Disorder
Interventions: BEHAVIORAL: The Sleep Train Program|BEHAVIORAL: The Family Mealtimes Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OTC Hearing Aid and MCI
Status: ENROLLING_BY_INVITATION
Conditions: Hearing Loss|Mild Cognitive Impairment
Interventions: DEVICE: Over the counter hearing aid|BEHAVIORAL: Communication Strategies Information/Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Prevention of Infection by COVID-19 in Workers
Status: COMPLETED
Conditions: COVID
Interventions: DIETARY_SUPPLEMENT: Group A: oropharygeal spray and immunostimulant emulsion|DIETARY_SUPPLEMENT: Group D:Placebo oropharyngeal spray + Placebo taken PO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Changes in Adiposity, Metabolic Measures From Atypicals to Aripiprazole
Status: COMPLETED
Conditions: Schizophrenia|Type 2 Diabetes Mellitus
Interventions: OTHER: Stayers|OTHER: Switchers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Pulse Stimulation Open-label Self-controlled Trial For Mild Neurocognitive Disorder
Status: UNKNOWN
Conditions: Mild Neurocognitive Disorder
Interventions: DEVICE: Transcranial Pulse Stimulation (TPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coenzyme Q10 Phase III Trial in Gulf War Illness
Status: COMPLETED
Conditions: Gulf War Illness|Chronic Fatigue|Ubiquinol|Coenzyme Q10
Interventions: DRUG: Ubiquinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PNF With and Without EMS on Spasticity, Gait and Lower Limb Function in Chronic Stroke Patients
Status: RECRUITING
Conditions: Chronic Stroke
Interventions: OTHER: Proprioceptive neuromuscular facilition|OTHER: Electrical muscle stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Bioavailability of Omeprazole 20 mg Before and After Undergoing Surgery for Morbid Obesity
Status: COMPLETED
Conditions: Bariatric Surgery Candidate
Interventions: DRUG: Omeprazole 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: To Compare the Ability of DiscoVisc® OVD to Protect the Corneal Endothelium and Maintain Anterior Chamber Space With Healon® and Amvisc® PLUS During Cataract Surgery.
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: DisCoVisc®|DRUG: Healon|DRUG: Amvisc Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Improving STEM Outcomes for Young Children With Language Learning Disabilities
Status: TERMINATED
Conditions: Specific Language Impairment
Interventions: BEHAVIORAL: Science + Phonological Awareness|BEHAVIORAL: Science + Grammar Intervention|BEHAVIORAL: Science + Vocabulary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety and Preliminary Activity of Eribulin Mesylate in Pediatric Participants With Relapsed/Refractory Rhabdomyosarcoma (RMS), Non-rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) and Ewing Sarcoma (EWS)
Status: COMPLETED
Conditions: Relapsed/Refractory Rhabdomyosarcoma|Non-rhabdomyosarcoma Soft Tissue Sarcoma|Ewing Sarcoma
Interventions: DRUG: Eribulin mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Study of the Efficacy and Tolerability of Tonabersat in the Prophylaxis of Migraine Headache
Status: COMPLETED
Conditions: Migraine Without Aura|Migraine With Aura
Interventions: DRUG: Tonabersat|DRUG: Tonabersat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Anodal Transcranial Direct Current Stimulation on Mobility and Balance in Post Stroke Patients.
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Anodal Transcranial Direct Current Stimulation Group|OTHER: Conventional Training Exercises Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin With Or Without Floxuridine and Leucovorin in Treating Patients With Metastatic Cancer of the Peritoneum
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: floxuridine|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal Cancer
Status: COMPLETED
Conditions: Anal Cancer|Carcinoma of the Appendix|Colorectal Cancer|Esophageal Cancer|Extrahepatic Bile Duct Cancer|Gallbladder Cancer|Gastric Cancer|Gastrointestinal Carcinoid Tumor|Gastrointestinal Stromal Tumor|Liver Cancer|Pancreatic Cancer|Small Intestine Cancer
Interventions: DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium|OTHER: pharmacogenomic studies|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: Cyanoacrylate Tissue Adhesives Versus Silk Suture at the Palatal Donor Site of Sub Epithelial Connective Tissue Graft
Status: UNKNOWN
Conditions: The Effect of Local Aplication of Cayanoacrylate Tissue Adhesives on Improving the Healing
Interventions: PROCEDURE: Cayanoacrylate tissue adhesives|PROCEDURE: Silk suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PCSK9 Inhibitors in the Progression of Aortic Stenosis
Status: UNKNOWN
Conditions: Aortic Valve Stenosis
Interventions: DRUG: PCSK9 Inhibitor [EPC]|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study Lp299v Supplementation in Chronic Heart Failure
Status: RECRUITING
Conditions: Heart Failure|Heart Failure With Reduced Ejection Fraction|Heart Failure, Systolic|Heart Failure With Preserved Ejection Fraction|Heart Failure, Diastolic
Interventions: OTHER: Lactobacillus Plantarum 299v Freeze Dried Capsule|OTHER: Freeze Dried Potato Starch Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fluorescence-guided Surgery Using cRGD-ZW800-1 in Oral Cancer
Status: RECRUITING
Conditions: Squamous Cell Carcinoma of the Head and Neck|Oral Cancer|Squamous Cell Carcinoma of the Oral Cavity
Interventions: DRUG: cRGD-ZW800-1.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vertical and Horizontal Alveolar Ridge Augmentation Using Autogenous Onlay Blocks Combined With Guided Bone Regeneration Using Native Collagen Membrane in Atrophic Anterior Maxilla.
Status: UNKNOWN
Conditions: Anterior Maxilla With Deficient Ridge Height and/or Width
Interventions: DEVICE: autogenous ring blockls with GBR covered by collagen membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CENTERA-2: Safety and Performance Study of the Edwards CENTERA-EU Self-Expanding Transcatheter Heart Valve
Status: COMPLETED
Conditions: Aortic Valve Disease
Interventions: DEVICE: Edwards CENTERA Self-Expanding Transcatheter Heart Valve
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor Bone Marrow Transplantation in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: DRUG: busulfan|DRUG: cyclophosphamide|DRUG: methylprednisolone|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: in vitro-treated bone marrow transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Peginterferon Plus Ribavirin for Hepatitis C Patients Concomitant With Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Chronic Hepatitis C|Hepatocellular Carcinoma
Interventions: DRUG: peginterferon alpha-2a and ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Gut Microbiota in Anastomoses Insufficiency After Resection and Direct Anastomosis for Colorectal Cancer.
Status: COMPLETED
Conditions: Colorectal Cancer, Peritoneal Carcinomatosis, Anastomosis Insufficiency
Interventions: PROCEDURE: Colectomy, CRS+HIPEC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multi-Dose Study to Assess Tolerability, Safety and Pharmacology of hGH-ViaDerm™ System in Adults With GH-Deficiency
Status: COMPLETED
Conditions: Growth Hormone Deficiency
Interventions: DRUG: hGH-ViaDerm™ System (hGH or somatropin)|DEVICE: hGH-ViaDerm™ System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Healthy Bacteria in Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: OTHER: Control|DRUG: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Acute Effects of Sn-1 and Sn-3 Palmitic Acid-rich or Stearic Acid-rich Fats on Metabolic Markers
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Palm Mid Fraction, Shea Butter, High Oleic Sunflower Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Testing the Addition of Ixazomib/Placebo to Lenalidomide in Patients With Evidence of Residual Multiple Myeloma, OPTIMUM Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspirate|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|DRUG: Ixazomib Citrate|DRUG: Lenalidomide|OTHER: Placebo Administration|PROCEDURE: Positron Emission Tomography|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Distraction Osteogenesis for Distal Radius Fractures vs. Volar Plating
Status: COMPLETED
Conditions: Distal Radius Fracture
Interventions: PROCEDURE: Dorsal Bridge Plating|PROCEDURE: Volar locking plating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Modification and Metformin Use in the Treatment of HIV
Status: COMPLETED
Conditions: HIV Infections|Metabolic Syndrome X
Interventions: DRUG: Metformin|DRUG: Placebo|BEHAVIORAL: Lifestyle Modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Functional Translation After Immersive Virtual Reality Exposure in Persons With Stroke
Status: COMPLETED
Conditions: Hemiparesis as Late Effect of Cerebrovascular Disease
Interventions: OTHER: Immersive virtual reality + related functional translation into real-life|OTHER: Immersive virtual reality + non-related translation into real-life
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-arm Phase II Study of Alemtuzumab in Combination With High-dose Methylprednisolone in CLL Patients With p53 Deletion
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukaemia
Interventions: DRUG: Alemtuzumab|DRUG: Methyprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate of the Efficacy of Enfuvirtide During the Induction Phase of Therapy
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Enfuvirtide|DRUG: Efavirenz, lamivudine, and tenofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesia iv vs Epidural Analgesia vs Port-sites Infiltration After Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Port-sites infiltration:Bupivacaine0.25%|DRUG: Epidural analgesia:Levobupivacaine0,125%|DRUG: Metamizole and Acetaminophen iv
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Immunogenicity and Safety of COVID-19 Vaccine , Inactivated in Children and Adolescents
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Inactivated COVID-19 Vaccine|BIOLOGICAL: Controlled vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Assessing the Prevalence of Attention Deficit Hyperactivity Disorder (ADHD) Symptoms in Undiagnosed Young Adults:A Cross Sectional Study
Status: COMPLETED
Conditions: Finding the Prevalence of ADHD in Undiagnosed Young Adults
Interventions: BEHAVIORAL: Behavioral diagnostic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluate the Safety and Explore the Efficacy of DWP712 With Moderate to Severe Glabellar Lines
Status: COMPLETED
Conditions: Glabellar Lines
Interventions: BIOLOGICAL: DWP712|BIOLOGICAL: BOTOX®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Dietary Biomarkers and Metabolic Effects After the Intake of Milk and Cheese
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: Cow´s milk (3.9% fat, pasteurized)|OTHER: hard, yellow cheese|OTHER: Soy based drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Human Papillomavirus (HPV) Self-sampling as a Test of Cure After Treatment of Cervical Intra-epithelial Neoplasia
Status: COMPLETED
Conditions: Cervical Intra-epithelial Neoplasia Grade 1 or Worse
Interventions: DEVICE: HPV self-testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Chemo Sensitization Before Hematopoietic Stem Cell Transplantation in Patients With Acute Leukemia in Complete Remission
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|Acute Lymphoid Leukemia
Interventions: DRUG: Busulfan|DRUG: Cyclophosphamide|DRUG: CXCR4 Antagonist|PROCEDURE: Hematopoietic Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spleen Stiffness Combined With Liver Stiffness Measured by 2D-SWE for the Screening of High-risk Varices in Compensated Advanced Chronic Liver Disease (CHESS2004)
Status: COMPLETED
Conditions: Compensated Advanced Chronic Liver Disease|Variceal Hemorrhage
Interventions: PROCEDURE: Esophagogasrtoduodendoscopy, spleen stiffness measurement and liver stiffness measurement.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Buspirone for Opioid Tapering
Status: COMPLETED
Conditions: Opioid-Related Disorders|Dependency (Psychology)|Pain, Chronic|Opiate Withdrawal Syndrome
Interventions: DRUG: Buspirone oral capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Harm Reduction for Tobacco Smoking With Support of Tobacco-Replacing Electronic Nicotine Delivery Systems
Status: UNKNOWN
Conditions: Smoking, Tobacco
Interventions: OTHER: HaRTS-TRENDS|OTHER: Standard Care (SC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: S0535, Gemtuzumab and Combination Chemotherapy in Treating Patients With Previously Untreated Acute Promyelocytic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: arsenic trioxide|DRUG: gemtuzumab ozogamicin|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: tretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Participant Reported Outcomes With Use of Trifarotene 50 μg/g Cream in the Treatment of Moderate Facial and Truncal Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Trifarotene
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effect of an Evidence-Based One Page With Supplemental Visual Aids on the Knowledge and Perceptions of Blood Pressure Management Among Adults With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Blood pressure education
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Remote Monitoring in Obstructive Sleep Apnea
Status: TERMINATED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Monitoring every 3 months by face-to-face visits|DEVICE: Frequent remote monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Non-invasive Respiratory Support on Outcome and Its Risks in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2)-Related Hypoxemic Respiratory Failure
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19|Hypoxemic Respiratory Failure
Interventions: DEVICE: High flow nasal oxygen (HFNO, more than 15 L/min)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adjunctive Transcranial Stimulation to Reduce Impulsivity in Opiate Use Disorder
Status: COMPLETED
Conditions: Opioid-use Disorder|Tobacco Use Disorder
Interventions: DEVICE: Theta Burst Stimulation|DEVICE: Sham TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Therapy of Nebido as Mono or in Combination With PDE-5 Inhibitors in Hypogonadal Patients With Erectile Dysfunction
Status: COMPLETED
Conditions: Hypogonadism|Erectile Dysfunction
Interventions: DRUG: Testosterone Undecanoate,1000mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension|Vascular Diseases|Cardiovascular Diseases
Interventions: DEVICE: Paradise Renal Denervation System|PROCEDURE: Renal Angiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab Combined With Apatinib for Perioperative Treatment of Resectable Primary Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Resectable Hepatocellular Carcinoma
Interventions: DRUG: Camrelizumab:200mg， iv，d1 q2w;apatinib:250mg,po，qd，q2w
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Abdominal Pain in Acute Gastroenteritis Patients With Hyoscine Butylbromide
Status: COMPLETED
Conditions: Acute Gastroenteritis|Abdominal Pain
Interventions: DRUG: Hyoscine N Butylbromide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dynamic Contrast Enhanced Magnetic Resonance Perfusion Imaging in Congenital Heart Disease and Lung Disease
Status: COMPLETED
Conditions: Heart Disease|Cystic Fibrosis|Asthma
Interventions: PROCEDURE: Phase contrast flow velocity mapping (PC)|PROCEDURE: Dynamic contrast-enhanced magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Post-placental Insertion of the Copper T 380A After Cesarean Delivery Versus 6 Week Post-cesarean Insertion
Status: COMPLETED
Conditions: Contraception
Interventions: OTHER: Immediate insertion|OTHER: 6 weeks interval insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: The Effects of Oxytocin on Social Touch
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: intranasal oxytocin|DRUG: intranasal placebo|DRUG: intranasal oxytocin|DRUG: intranasal placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy Mechanism of N-acetylcysteine in Patients With Posttraumatic Stress Disorder
Status: WITHDRAWN
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: N-acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective, Non-interventional, Post-authorization Safety Study That Includes All Patients Diagnosed as Unresectable Differentiated Thyroid Carcinoma and Treated With Sorafenib
Status: ACTIVE_NOT_RECRUITING
Conditions: Thyroid Carcinoma
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Epiretinal Macular Membrane and Cataract Extraction
Status: COMPLETED
Conditions: Epiretinal Macular Membrane|Cataract Extraction
Interventions: PROCEDURE: Consecutive surgery|PROCEDURE: Combined surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Indocyanine Green Fluorescent Imaging in Robotic Assisted Rectosigmoidal Resection; a Multicenter Assessment of Interobserver Variation and Comparison With Computer-based Pixel Analysis
Status: COMPLETED
Conditions: Colorectal Cancer|Anastomotic Leak
Interventions: OTHER: Fluorescent Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intercalating and Maintenance Use of Iressa Versus Chemotherapy in Selected Advanced Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Gefitinib|DRUG: Gemcitabine +Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Market Clinical Follow-Up to Access & Visualize the Anus, Rectum, & Distal Colon During Transanal Procedures
Status: UNKNOWN
Conditions: Disease or Lesions of the Anus, Rectum, or Distal Colon
Interventions: DEVICE: Transanal endoscopic surgical procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 14-day Quadruple Hybrid vs. Concomitant Therapies for Helicobacter Pylori Eradication
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: PPI, amoxicillin, metronidazole and clarithromycin|DRUG: PPI, amoxicillin, metronidazole and clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microwave Ablation and Surgical Resection for Micropapillary Thyroid Carcinoma
Status: UNKNOWN
Conditions: Papillary Thyroid Carcinoma
Interventions: PROCEDURE: Microwave ablation|PROCEDURE: Surgical resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Economic Comparison of Percutaneous (pEVAR) vs. Open Access in EVAR.
Status: COMPLETED
Conditions: Aortic Aneurysm
Interventions: DEVICE: pEVAR|PROCEDURE: open femoral access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of STAR-0215 in Healthy Adult Participants
Status: COMPLETED
Conditions: Hereditary Angioedema
Interventions: DRUG: STAR-0215 (SC)|DRUG: Placebo (SC)|DRUG: STAR-0215 (IV)|DRUG: Placebo (IV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of MTRPs Therapy in Migraine.
Status: RECRUITING
Conditions: Migraine|Pain, Shoulder|Trapezius Muscle Strain Left|Trapezius Muscle Strain Right|Muscle Pain|Trigger Point Pain, Myofascial|Cervical Pain
Interventions: OTHER: Ischemic Compression of Myofascial Trigger Points (IC-MTRPs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PSMA-PET Registry for Recurrent Prostate Cancer
Status: RECRUITING
Conditions: Recurrent Prostate Cancer
Interventions: DIAGNOSTIC_TEST: [18F]-DCFPyL PET/ CT scan (PSMA PET)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Laughter Yoga on Mindfulness, Proffessional Resilience and Self-Care
Status: NOT_YET_RECRUITING
Conditions: Laughter Yoga|Laughter Therapy|Mindfulness|Self-care
Interventions: BEHAVIORAL: Laughter Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Clinical Study to Evaluate the Remote Monitoring of Myopia Patients With the EyeQue Insight
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Visual Acuity with a Hand-held Device Supported by Mobile App.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study to Investigate the Safety and Efficacy of Replenine®-VF in Haemophilia B Patients Undergoing Major Surgery.
Status: COMPLETED
Conditions: Haemophilia B
Interventions: BIOLOGICAL: Replenine®-VF (High Purity Factor IX)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Improving Quality of Life and Daily Life Activities With Bioarginine in Patients With COPD
Status: RECRUITING
Conditions: COPD|Dyspnea|Argininemia
Interventions: DRUG: Arginine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Maintenance Treatment With Fluzoparib Versus Placebo in Relapsed Ovarian Cancer Patients
Status: UNKNOWN
Conditions: Ovarian Cancer
Interventions: DRUG: Fluzoparib capsules|DRUG: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Booster Sessions on Depression Vulnerability Following Cognitive Control Training
Status: RECRUITING
Conditions: Major Depression in Remission
Interventions: BEHAVIORAL: Cognitive Control Training (CCT)|BEHAVIORAL: Cognitive Control Training (CCT) + Booster Sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intravitreal Dexamethasone Implant in Retinitis Pigmentosa-related Macular Edema- a Retrospective Study
Status: UNKNOWN
Conditions: Retinitis Pigmentosa|Cystoid Macular Edema
Interventions: DEVICE: dexamethasone injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Piracetam Taken for 12 Months in Subjects Suffering From Mild Cognitive Impairment (MCI)
Status: COMPLETED
Conditions: Memory Disorders
Interventions: DRUG: Piracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Cisplatin With or Without CPI-613 as First Line Therapy for Patients With Advanced Unresectable Biliary Tract Cancer (BilT-04)
Status: COMPLETED
Conditions: Biliary Tract Cancer
Interventions: DRUG: CPI 613|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prader-Willi Syndrome Macronutrient Study
Status: COMPLETED
Conditions: Prader Willi Syndrome|Syndromic Obesity|Childhood Obesity
Interventions: OTHER: Low Carbohydrate diet|OTHER: Low Fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Changes in Pulmonary Ventilation Distribution Assessed by Electrical Impedance Tomography in Healthy Children Under General Anesthesia
Status: RECRUITING
Conditions: Anesthesia, Pediatric
Interventions: PROCEDURE: General anesthesia with mask ventilation|PROCEDURE: General anesthesia and spontaneous laryngeal mask ventilation|PROCEDURE: General anesthesia with spontaneous laryngeal mask ventilation with pressure support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: DDAVP in the Reduction of Post-operative Ecchymosis in Rhinoplasty
Status: TERMINATED
Conditions: Postoperative Ecchymosis
Interventions: DRUG: DDAVP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intranasal Fentanyl in Combination With Midazolam Versus Midazolam Alone for Pediatric Facial Laceration Repair
Status: UNKNOWN
Conditions: Facial Laceration|Anxiety
Interventions: DRUG: Intranasal Fentanyl Spray and Intranasal Midazolam Spray|DRUG: Intranasal Midazolam Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NT-proBNP Selected Prevention of Cardiac Events in Diabetic Patients
Status: RECRUITING
Conditions: Heart Diseases|Diabetes Mellitus, Type 2
Interventions: DRUG: RAS-antagonist and beta-blocker up-to maximal dosages|OTHER: RAS-antagonist and beta-blocker none or at stable dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Public Access Defibrillation (PAD) Community Trial
Status: COMPLETED
Conditions: Arrhythmia|Heart Arrest|Heart Diseases|Myocardial Infarction|Ventricular Fibrillation|Death, Sudden, Cardiac
Interventions: DEVICE: defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: ET50 With Fentanyl for Post Caesarean Section Spinal Hypotension
Status: UNKNOWN
Conditions: Hypotension|Pregnancy
Interventions: DRUG: Bupivacaine with 15 micrograms of fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transesophageal Magnetic Resonance Imaging (MRI) in Conjunction With Lipid Lowering Measures
Status: COMPLETED
Conditions: Heart Diseases
Interventions: DRUG: Simvastatin (20mg versus 80mg/day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Music Therapy on Sleep Disorders
Status: UNKNOWN
Conditions: Sleep Disorder|Chronic Insomnia
Interventions: OTHER: Music therapy with Music Care app|OTHER: Sound therapy with White Noise|OTHER: Treatment as usual for sleep disorders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerance, and Pharmacokinetics of BILN 2061 ZW in Healthy Male Subjects, Combined With Preliminary Evaluation of Food Effect
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BILN 2061 ZW single rising doses|DRUG: Placebo|DRUG: BILN 2061 ZW fixed dose|OTHER: Standardized breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Oral Colchicine Combined With Intravitreal Infusion of Dexamethasone, LMW Heparin and 5-FU for Management of Proliferative Vitreoretinopathy (PVR)
Status: UNKNOWN
Conditions: Proliferative Vitreoretinopathy
Interventions: DRUG: oral colchicine, dexamethasone, low molecular weight heparin, 5-FU|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Free-living Validation of the RFPM in Adolescents
Status: ACTIVE_NOT_RECRUITING
Conditions: Dietary Assessment|Energy Intake|Food Intake|Food Photography
Interventions: OTHER: Tests of the validity of the RFPM and SmartIntake app.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Buprenorphine and Integrated HIV Care
Status: COMPLETED
Conditions: Substance-related Disorders|Drug Addiction|Human Immunodeficiency Virus|AIDS|HIV Infections
Interventions: OTHER: Physician Management|BEHAVIORAL: Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Improving ATTENDance to Cardiac Rehabilitation Trial
Status: COMPLETED
Conditions: Myocardial Infarction|Heart Failure|Heart Valve Diseases|Cardiac Event|Angina Pectoris|Coronary Artery Disease
Interventions: BEHAVIORAL: HYCR|BEHAVIORAL: CBCR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tizanidine vs. Zolpidem in Primary Insomnia: A Randomized Trial
Status: NOT_YET_RECRUITING
Conditions: Depressive Disorder, Major
Interventions: DRUG: Tizanidine Hcl 4Mg Tab|DRUG: Zolpidem Tartrate 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Proxinium Plus Best Supportive Care Versus Best Supportive Care for Patients With Advanced Head and Neck Cancer
Status: TERMINATED
Conditions: Carcinoma, Squamous Cell of Head and Neck|Carcinoma, Squamous Cell|Neoplasms, Squamous Cell|Head and Neck Neoplasms|Mouth Neoplasms|Head and Neck Cancer
Interventions: DRUG: Proxinium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults for COVID-19
Status: COMPLETED
Conditions: Severe Acute Respiratory Syndrome|Coronavirus|SARS-CoV-2|COVID-19
Interventions: BIOLOGICAL: CVnCoV Vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Essence of Chicken on Physical Fatigue, Working Memory and Attention
Status: COMPLETED
Conditions: Healthy Subjects|Fatigue
Interventions: DIETARY_SUPPLEMENT: Essence of Chicken|DIETARY_SUPPLEMENT: Placebo (Energy matched)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thyroxine Therapy for Recurrent Pregnancy Loss in Hypothyroid Women
Status: COMPLETED
Conditions: Recurrent Early Pregnancy Loss|Thyroid Diseases
Interventions: DRUG: Levothyroxine Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BIBF 1120 in Combination With Pemetrexed in Advanced Non Small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: BIBF 1120 M + Pemetrexed|DRUG: BIBF 1120 H + Pemetrexed|DRUG: BIBF 1120 RD + Pemetrexed|DRUG: BIBF 1120 L + Pemetrexed|DRUG: BIBF 1120 Placebo + Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: NSPT On Vitronectin And Fetuin-A Levels In Patients With Periodontitis And Coronary Artery Disease
Status: NOT_YET_RECRUITING
Conditions: Chronic Periodontitis|Cardiovascular Diseases|Periodontal Inflammation
Interventions: OTHER: Non Surgical Periodontal Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Number of Inseminated Spermatozoa on Subsequent Human Embryonic Development in Vitro
Status: COMPLETED
Conditions: Spermatozoa and Embryos
Interventions: PROCEDURE: Insemination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ilorasertib in Treating Patients With CDKN2A-deficient Advanced or Metastatic Solid Cancers That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Metastatic Malignant Neoplasm|Solid Neoplasm|Unresectable Malignant Neoplasm
Interventions: DRUG: Ilorasertib|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Post Discharge Utilization Among Patients With an Acute Exacerbation of COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Usual Care|OTHER: COPD Clinical Pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Evaluation of a Powered Vascular Stapler in Laparoscopic Nephrectomies and Nephroureterectomies
Status: COMPLETED
Conditions: Excision of Kidney
Interventions: DEVICE: Surgeon's 'standard of care' stapler|DEVICE: Ethicon Powered Vascular Stapler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Program for Cancer Related Cachexia Prevention
Status: RECRUITING
Conditions: Neoplasms|Cancer|Cachexia|Malnutrition|Educational Problems
Interventions: OTHER: Multimodal education and support program for cancer related cachexia prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Efficacy and Safety of Co-administrated Rosuvastatin/Ezetimibe and Telmisartan/Amlodipine
Status: COMPLETED
Conditions: Hypercholesterolemia|Hypertension
Interventions: DRUG: Ezetimibe/Rosuvastatin|DRUG: Telmisartan|DRUG: Telmisartan/Amlodipine 80 Mg-5 Mg ORAL TABLET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Staining and Calculus Formation After 0.12% Chlorhexidine Rinses
Status: COMPLETED
Conditions: Dental Calculus|Tooth Discoloration
Interventions: OTHER: Dental prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The MATCH Investigation: CT Myocardial Perfusion and CT-FFR vs PET MPI
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: PET-MPI Protocol|DIAGNOSTIC_TEST: CT-MPI|DIAGNOSTIC_TEST: CT-FFR|DRUG: Regadenoson
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC