pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Split Course Adaptive Radiation Therapy With Pembrolizumab With/Without Chemotherapy for Treating Stage IV Lung Cancer
Status: SUSPENDED
Conditions: Lung Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8|Stage III Lung Cancer
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Carboplatin|PROCEDURE: Computed Tomography|OTHER: Fludeoxyglucose F-18|DRUG: Nab-paclitaxel|BIOLOGICAL: Pembrolizumab|DRUG: Pemetrexed|PROCEDURE: Positron Emission Tomography|RADIATION: Radiation Therapy|OTHER: [18-F] (fluoropropyl)-L-glutamate (FSPG) PET scan|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab|BIOLOGICAL: Cemiplimab|BIOLOGICAL: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, PK and Efficacy of 15 Days of SCY-635 Treatment in Hepatitis C Patients
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Placebo|DRUG: SCY-635
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Aspirin and Simvastatin in Pulmonary Arterial Hypertension
Status: TERMINATED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Simvastatin|DRUG: Aspirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of 21-day Purification Program on Healthy Adults
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Standard Process 21-Day Purification Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Epratuzumab Versus Placebo in Subjects With Moderate to Severe General Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Epratuzumab|DRUG: Epratuzumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of IST Combined With TPO-RA in the Treatment of AA and Establishment of a Recurrence Prediction System
Status: RECRUITING
Conditions: Aplastic Anemia|CSA|Drug Therapy
Interventions: DRUG: CsA+ATG+Herombopag|DRUG: CsA+Herombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention Using Exercise Rehabilitation to Offset Cardiac Toxicities Induced Via Chemotherapy
Status: COMPLETED
Conditions: Doxorubicin Induced Cardiomyopathy|Breast Cancer|Gastric Cancer|Leukemia
Interventions: OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Recovery, Excretion and Pharmacokinetics of [14C]-GSK2140944 Administered as a Single Intravenous and Single Oral Dose to Healthy Adult Male Subjects
Status: COMPLETED
Conditions: Infections, Respiratory Tract
Interventions: DRUG: GSK2140944 for Injection|DRUG: GSK2140944 Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Neuroscience Pain Education on Quality of Life in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain|Quality of Life|Pain
Interventions: OTHER: Neuroscience pain education|OTHER: Traditional patient education|OTHER: Manual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is the Artificial Pancreas, Without Carbohydrate Counting, Efficient and Safe in an Outpatient Setting
Status: COMPLETED
Conditions: Type 1 Diabetes|Autoimmune Diabetes
Interventions: DEVICE: Non-hybrid closed-loop system with ARG algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Health Effects of Oat and Oat Bioactive in Human
Status: COMPLETED
Conditions: Postprandial Glucose Regulation
Interventions: COMBINATION_PRODUCT: Effects of Oat and Oat Components on Cardiometabolic risk variables
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Sipuleucel-T With or Without Radiation Therapy in Treating Patients With Hormone-Resistant Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Bone Metastases|Hormone-resistant Prostate Cancer|Recurrent Prostate Cancer|Soft Tissue Metastases|Stage IV Prostate Cancer
Interventions: BIOLOGICAL: sipuleucel-T|RADIATION: external beam radiation therapy|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Use of Ganciclovir Gel 0.3% for the Treatment of Conjunctivitis Caused by Adenovirus
Status: UNKNOWN
Conditions: Conjunctivitis|Adenovirus.
Interventions: DRUG: Ophthalmic gel (placebo)|DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single Port Access (SPA) Cholecystectomy Versus Standard Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Symptomatic Gallbladder Stones|Cholecystitis|Biliary Pancreatitis
Interventions: PROCEDURE: SPA cholecystectomy|PROCEDURE: Laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of ELX/TEZ/IVA on Glucose Tolerance in Participants With Cystic Fibrosis (CF)
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: ELX/TEZ/IVA|DRUG: IVA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serratus Plane Block and Pectointercostal Block
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: PROCEDURE: ultrasound guided Serratus plane bock and pectointercostal block|PROCEDURE: ultrasound guided Serratus plane bock
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Innovative Probiotic Product With Antiallergic Properties
Status: COMPLETED
Conditions: Atopic Dermatitis|Food Allergy|Effects of Probiotics
Interventions: DIETARY_SUPPLEMENT: Probiotic preparation|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cross-linked Collagen Membrane With and Without Silk Fibroin Around Immediate Dental Implants
Status: NOT_YET_RECRUITING
Conditions: Immediate Implant
Interventions: OTHER: collagen with silk fibroin membrane|OTHER: cross linked collagen membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of ProCalcitonin for the Detection of Bacteraemia in Patients Presenting to the Emergency Department for Low Risk Chemo-induced Febrile Neutropenia
Status: TERMINATED
Conditions: Febrile Neutropenia, Drug-Induced
Interventions: DIAGNOSTIC_TEST: Value of ProCalcitonin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Beta 2 Adrenergic Stimulation vs Cold Exposure to Activate Human Brown Adipose Tissue
Status: COMPLETED
Conditions: Thermogenesis
Interventions: DRUG: Fenoterol|OTHER: Mild cold exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Single-center, Randomized, Double-blinded, Placebo-controlled, Phase 1 Clinical Trial to Evaluate the Safety, Tolerability and Efficacy of NCP112
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: NCP112
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Lifestyle on Sperm Telomere Length and Telomerase Activity in Men Undergoing IVF Treatments
Status: UNKNOWN
Conditions: Male Infertility
Interventions: OTHER: DNeasy Tissue Kit (QIAGEN Inc., Mississauga, Ontario, Canada) and PCR- based assay (TRAPeze Telomerase Detection Kit; Millipore, Billerica, MA).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tardive Dyskinesia and Cognitive Function
Status: COMPLETED
Conditions: Tardive Dyskinesia|Neurocognitive Function
Interventions: DRUG: amisulpride|DRUG: Olanzapine|DRUG: Conventional antipsychotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of MP-376 Given for 28 Days to Cystic Fibrosis (CF) Patients
Status: COMPLETED
Conditions: Cystic Fibrosis (CF)
Interventions: DRUG: MP-376|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of TT30 in Subjects With Paroxysmal Nocturnal Hemoglobinuria (PNH)
Status: TERMINATED
Conditions: Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions: DRUG: ALXN1102|DRUG: ALXN1103
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NKX019, Intravenous Allogeneic Chimeric Antigen Receptor Natural Killer Cells (CAR NK), in Adults With Autoimmune Disease (Ntrust-1)
Status: RECRUITING
Conditions: Lupus Nephritis|Glomerulonephritis
Interventions: DRUG: NKX019|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Immunogenicity, Safety and Efficacy of COVID-19 Vaccines in Immunosuppressed Individuals
Status: UNKNOWN
Conditions: Hematologic Neoplasms|COVID-19 Vaccines
Interventions: DIAGNOSTIC_TEST: S-binding IgG, RBD-binding IgG and N-binding IgG immunoassays and SARS-CoV-2 serum neutralization assay, quantitative serum immunoglobulin tests|DIAGNOSTIC_TEST: Assessment of proinflammatory cytokine production and immunophenotypic analysis after stimulation with overlapping S-peptides in peripheral blood mononuclear cells (PBMC)|DIAGNOSTIC_TEST: Quantitative sequencing for TCR repertoires for SARS-CoV-2-specific antigens
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: THe Comparison of Target Controlled Infusion of Propofol or Etomidate at General Anesthesia in Geriatric Patients
Status: UNKNOWN
Conditions: Adrenal Suppression|Hemodynamic Instability
Interventions: DRUG: Remifentanil|DRUG: Cisatracurium|DRUG: Sufentanil|DEVICE: Bispectral index(BIS) monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Clinical Efficacy and Safety of Diabetes-Specific Formula (Nutren Diabetes)
Status: RECRUITING
Conditions: Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Nutren Diabetes|DIETARY_SUPPLEMENT: Fresubin Diabetes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Stage IIIA Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Stage IIIA Non-small Cell Lung Cancer
Interventions: DRUG: paclitaxel|DRUG: carboplatin|DRUG: motexafin gadolinium|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation in Breastfeeding Women
Status: COMPLETED
Conditions: Vitamin D Deficiency|Rickets|Infant Nutrition Disorders
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Integrated Smoking Cessation and Alcohol Intervention for Young People
Status: UNKNOWN
Conditions: Smoking Cessation|Alcohol Drinking
Interventions: BEHAVIORAL: Standard treatment (ST) arm|OTHER: Integrated Intervention (II) arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Optimal Sequencing of Treatment Options for Poor Risk mCRPC Previously Treated With Docetaxel
Status: COMPLETED
Conditions: Prostate Cancer Metastatic|Metastasis
Interventions: DRUG: Cabazitaxel|DRUG: Abiraterone|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cannabinoids vs. Placebo on Persistent Post-surgical Pain Following TKA: A Pilot RCT
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DRUG: MPL-001 (CBD: THC 25:1)|DRUG: Placebo oil for oral use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Letrozole Plus Low-Dose Metronomic Capecitabine Versus EC-T (Epirubicin/Cyclophosphamide Followed by Docetaxel) as Neoadjuvant Therapy for ER+/HER2-negative Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Letrozole Plus Low-Dose Metronomic Capecitabine|DRUG: EC-T
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Safety and Efficacy Study to Evaluate AMG 531 Treatment in Subject With Myelodysplastic Syndrome Receiving Revlimid
Status: COMPLETED
Conditions: Myelodysplastic Syndromes|Thrombocytopenia
Interventions: BIOLOGICAL: AMG 531|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety & Efficacy of Lamivudine & Tenofovir to Lower Plasma Level of Viral RNA in Lymphoma
Status: WITHDRAWN
Conditions: Lymphoma
Interventions: DRUG: Lamivudine|DRUG: Tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Desmopressin (Nocturin®) 0.1 mg Tablets in Treatment of Nocturia in Participants With Benign Prostate Syndrome (BPS)
Status: COMPLETED
Conditions: Nocturia Associated With Nocturnal Polyuria
Interventions: DRUG: desmopressin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Incidence of Hypophosphatemia After Treatment With Iron Isomaltoside/Ferric Derisomaltose or Ferric Carboxymaltose in Subjects With Iron Deficiency Anaemia
Status: COMPLETED
Conditions: Iron Deficiency Anaemia|Iron Deficiency Anemia
Interventions: DRUG: Iron isomaltoside/ferric derisomaltose|DRUG: Ferric carboxymaltose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Nuun Instant on Hydration Status in Active Men and Women
Status: COMPLETED
Conditions: Hydration
Interventions: DIETARY_SUPPLEMENT: Nuun Instant|OTHER: Water|DIETARY_SUPPLEMENT: Nuun Electrolyte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Monotherapy With P2Y12 Inhibitors in Patients With Atrial fIbrillation Undergoing Supraflex Stent Implantation
Status: RECRUITING
Conditions: Percutaneous Coronary Intervention (PCI)|Atrial Fibrillation (AF)|Oral Anticoagulation|P2Y12 Inhibitor
Interventions: DRUG: P2Y12 inhibitor|DRUG: Aspirin|DRUG: DOAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma
Status: RECRUITING
Conditions: Pleural Biphasic Mesothelioma|Pleural Sarcomatoid Mesothelioma
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab|PROCEDURE: Surgical Procedure|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid Response to Day Hospital Treatment in Bulimia Nervosa and Purging Disorder
Status: COMPLETED
Conditions: Bulimia Nervosa|Eating Disorder
Interventions: BEHAVIORAL: Cognitive Behavior Therapy (CBT)|BEHAVIORAL: Motivational Interviewing (MI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ethanol Lock Therapy for Treatment and Secondary Prophylaxis of Central Line-Associated Bloodstream Infection
Status: COMPLETED
Conditions: Central Line-Associated Bloodstream Infection
Interventions: DRUG: ethanol|DRUG: heparin-saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of CG53135-05 in the Prevention of Oral Mucositis in Patients Receiving Bone Marrow Transplant
Status: COMPLETED
Conditions: Stomatitis
Interventions: DRUG: CG53135-05, velafermin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Salt Water Gargling on Swallowing Following ACDF
Status: NOT_YET_RECRUITING
Conditions: Degeneration Spine|Cervical Radiculopathy|Cervical Stenosis|Cervical Spondylosis|Cervical Myelopathy|Dysphagia
Interventions: OTHER: Sodium chloride gargle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Impact of the Practice of Touch-massage on the Anxiety of Patients With Hematological Disorders Hospitalized in a Protective Environment, a Randomized, Controlled Study
Status: COMPLETED
Conditions: Hematologic Diseases
Interventions: OTHER: Touch-massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Paracetamol Vs Caffeine Vs Codeine in the Management of Post Traumatic Pain in Emergencies
Status: COMPLETED
Conditions: Acute Pain Due to Trauma
Interventions: DRUG: Paracetamol|DRUG: Paracetamol Codeine|DRUG: Paracetamol caféine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Mechanical Insufflation-exsufflation on Airway Mucus Clearance in the ICU
Status: UNKNOWN
Conditions: Respiratory Failure
Interventions: OTHER: Mechanical insufflation-exsufflation|OTHER: Standard Respiratory Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TPC Versus GP Induction Chemotherapy for Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: TPC induction chemotherapy|DRUG: GP induction chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cutaneous Microcirculation and Nervous Sensitivity in Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: OTHER: Acetylcholine iontophoresis|OTHER: Sodium Nitroprussiate iontophoresis|OTHER: ppi water iontophoresis|OTHER: Laser Doppler recording
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immune Response to SARS-CoV-2/COVID-19 Vaccination in Sarcoidosis
Status: COMPLETED
Conditions: Sarcoidosis|SARS-CoV2 Infection|Vaccine Response Impaired
Interventions: DIAGNOSTIC_TEST: Assay of (1) the level of anti-spike IgG antibody, and (2) interferon-gamma release in response to SARS-CoV-2 antigen stimulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Study of an Olfactory Stimulation Program for the Recuperation of Autobiographical Memories in Anorexia
Status: COMPLETED
Conditions: Anorexic
Interventions: BEHAVIORAL: olfactory stimulation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Melphalan Followed by Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: filgrastim|DRUG: melphalan|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Cytomegalovirus (CMV) Perilymphatic Fluid
Status: UNKNOWN
Conditions: Hearing Loss, Cochlear|Cytomegalovirus Congenital
Interventions: BIOLOGICAL: collection of sample of perilymphatic fluid during cochlear implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy of 20 mg Parecoxib as an Adjunct to 0.75% Ropivacaine in Supraclavicular Brachial Plexus Block for Upper Limb Surgery
Status: COMPLETED
Conditions: Anesthesia; Functional|Anesthesia
Interventions: DRUG: Parecoxib 20 MG/ML|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Sativex in the Treatment of Central Neuropathic Pain Due to Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Neuropathic Pain
Interventions: DRUG: Placebo|DRUG: Sativex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Women With Chest Pain and no Significant Coronary Artery Stenosis; A Study on Microvascular Resistance
Status: COMPLETED
Conditions: Angina Pectoris
Interventions: DRUG: Rosuvastatin|DRUG: Placebo.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Morphometric and Cyto/Histological Combined Pre-operative Assessment of Inguinal Lymph Node Status in Women With Invasive Vulvar Carcinoma
Status: UNKNOWN
Conditions: Vulvar Cancer
Interventions: PROCEDURE: Groin ultrasound +/- fine needle aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: GRN1005 in Non-Small Cell Lung Cancer (NSCLC) Patients With Brain Metastases (GRABM-L)
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer (NSCLC) With Brain Metastases
Interventions: DRUG: GRN1005
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Discharge Opioid Reduction Intervention for Open, Laparoscopic, and Endoscopic Surgery
Status: COMPLETED
Conditions: Prostate Cancer|Opioid Use
Interventions: BEHAVIORAL: Opioid Reduction Intervention|BEHAVIORAL: Current Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety Clinical Trial With Depigopid 50% Grasses/50% Olea Europaea(2000DPP/ml) or Depigoid 50% Grasses/50% Parietaria Judaica(2000DPP/ml).
Status: COMPLETED
Conditions: Allergy|Rhinitis|Rhinoconjunctivitis|Seasonal Asthma
Interventions: DRUG: Depigoid 50% Grasses/50% Olea europaea (2000DPP/ml)|DRUG: Depigoid 50% Grasses/50% Parietaria judaica (2000DPP/ml)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study With Infigratinib in Subjects With Advanced Solid and CNS Tumors or Recurrent or Progressive Low-Grade Glioma With Selected FGFR1-3 Alterations
Status: WITHDRAWN
Conditions: Advanced Solid Tumor|CNS Tumor|Recurrent WHO Grade II Glioma
Interventions: DRUG: Infigratinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Urticaria - Long Term Assessment of Effects of Rupatadine
Status: TERMINATED
Conditions: Chronic Urticaria
Interventions: DRUG: 10 mg Rupatadine on demand|DRUG: 10 mg Rupatadine|DRUG: 20 mg Rupatadine|DRUG: 10 mg Rupatadine on demand (sham updosing to 20 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Qing'E Formula Therapy on Menopausal Symptoms
Status: COMPLETED
Conditions: Menopause
Interventions: DRUG: Qing'E pills|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aminophylline on Perioperative Lung Mechanics in COPD Morbidly Obese Patients Undergoing Laparoscopic Bariatric Surgery
Status: RECRUITING
Conditions: Aminophylline|Chronic Obstructive Pulmonary Disease|Obese|Laparoscopic Bariatric Surgery|Dexmedetomidine|Lung Mechanics
Interventions: DRUG: Aminophylline-Dexmedetomidine|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of Novel Postpartum Educational Video Intervention
Status: COMPLETED
Conditions: Behavior|Communication|Language
Interventions: OTHER: TMW-Newborn Intervention video|OTHER: Safe Sleep for your Baby (SIDS) educational video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effect of Mulberry Leaf Extract on Blood Glucose
Status: COMPLETED
Conditions: Prediabetic State
Interventions: DIETARY_SUPPLEMENT: Mulberry leaf extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mass Screening and Treatment for Reduction of Falciparum Malaria
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria
Interventions: DIAGNOSTIC_TEST: Ultrasensitive Rapid Diagnostic Test (URDT)|DRUG: Antimalarials
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Clinical Performance of Fiber Reinforced Composite Versus Microhybrid Composite Restorations
Status: COMPLETED
Conditions: Dental Restoration Failure of Marginal Integrity
Interventions: OTHER: Fiber reinforced resin composite restoration|OTHER: Microhybrid resin composite restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Observer Presence and Type on Patients' Perception of Exercise in Patients With Soft Tissue Sarcoma
Status: NOT_YET_RECRUITING
Conditions: Soft Tissue Sarcoma
Interventions: OTHER: Supervised Exercise by a physiotherapist via face to face
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N-Acetylcysteine and Arginine Administration in Diabetic Patients
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus|Hypertension
Interventions: DRUG: Arginine|DRUG: Acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of GW468816, an NMDA Glycine Site Antagonist, for Prevention of Relapse to Smoking
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: GW468816|DRUG: Placebo Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Single-blinded, Randomized, Placebo Controlled Phase II Trial of Prophylactic Treatment With Oral Azithromycin Versus Placebo in Cancer Patients Undergoing Antineoplastic Treatment During the Corona Virus Disease 19 (COVID-19) Pandemic
Status: COMPLETED
Conditions: COVID
Interventions: DRUG: Azithromycin 500 milligram (mg) oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of RTA 402 in Chronic Kidney Disease (CKD) Patients With Type 2 Diabetes Mellitus
Status: TERMINATED
Conditions: Chronic Kidney Disease|Type 2 Diabetes
Interventions: DRUG: RTA 402
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Intra-articular Steroid Injection and Radiofrequency Thermocoagulation in Coxarthrosis Patients
Status: UNKNOWN
Conditions: Pain Hip Burning
Interventions: PROCEDURE: Radiofrequency thermocoagulation of sensory branches of hip joint|PROCEDURE: Intraarticular steroid injection of hip joint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Use of Topical Nasal Steroids for Skin Reactions to Continuous Glucose Monitoring System, Among Children and Youth With Type 1 Diabetes Mellitus: Case Series
Status: COMPLETED
Conditions: T1DM|Hypersensitivity
Interventions: DRUG: Fluticasone Propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of HX008 in Combination With Bevacizumab or Lenvatinib for the Treatment of Advanced Hepatocellular Carcinoma (HCC)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: HX008|DRUG: Bevacizumab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Pharmacokinetics of Three Generic Medications and Their Respective Brand Preparations
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Trazodone|DRUG: Quetiapine|DRUG: Pindolol|PROCEDURE: Blood Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Meloxicam Nanocrystal Injection for the Treatment of Moderate to Severe Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Meloxicam Nanocrystal Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Practice Guidelines Versus Decision-support for Latent Tuberculosis Infection (LTBI) Management
Status: COMPLETED
Conditions: Latent Tuberculosis
Interventions: BEHAVIORAL: CDC/NTCA guidelines only|BEHAVIORAL: LTBI ASSIST and CDC/NTCA guidelines only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of 1-week Triple Therapy With Ilaprazole for the Eradication of Helicobacter Pylori
Status: COMPLETED
Conditions: Helicobacter Pylori Eradication
Interventions: DRUG: Ilaprazole|DRUG: Esoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NET-PD LS-1 Creatine in Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: DRUG: creatine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Light-Therapy in the Treatment of the Acute Phase of the Bipolar Type II Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Bipolar Type II Disorder|Depression, Bipolar
Interventions: DEVICE: Northern Light Technology (SADelite lamp) bright light-therapy|DEVICE: Northern Light Technology (SADelite lamp) Dim light-therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Radiotherapy With or Without CBDCA in Elderly Patients With Non-Small Cell Lung Cancer (JCOG0301)
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: PROCEDURE: A: Radiotherapy alone|DRUG: B: CBDCA and Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: sCD163 and sMR in Wilsons Disease - Associations With Disease Severity and Fibrosis
Status: COMPLETED
Conditions: Wilsons Disease
Interventions: PROCEDURE: Fibroscan|PROCEDURE: Ultrasound|DRUG: Galactose|PROCEDURE: Liver biopsy|PROCEDURE: Functional hepatic nitrogen clearance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Online Multi-component Psychological Intervention for Healthcare Workers During COVID-19 Pandemic
Status: UNKNOWN
Conditions: Anxiety|Depression|Sleep Disturbance|Quality of Life|Burnout, Professional|Stress|Fatigue, Compassion
Interventions: BEHAVIORAL: Online psychological intervention for healthcare workers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Safety and Efficacy of IM96 CAR-T Cells Therapy in Patients With Advanced Digestive System Neoplasms
Status: UNKNOWN
Conditions: Advanced Solid Tumors|Digestive System Neoplasms|Pancreatic Cancer Resectable|Colorectal (Colon or Rectal) Cancer
Interventions: DRUG: IM96 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Necessity of an Injection-Meal-Interval in Patients With Type 2 Diabetes Mellitus and Therapy With Human Insulin
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: PROCEDURE: injection-meal-interval
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy of Early Physical Therapy Intervention Following a Modified Unilateral Neck Dissection for Treatment of Head and Neck Cancer
Status: COMPLETED
Conditions: Shoulder Weakness Following Neck Dissection Surgery
Interventions: OTHER: Physical therapy intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of MEDI-524 in Healthy Adults
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: MEDI-524 (Numax-TM)|BIOLOGICAL: MEDI-524 (Numax-TM)|BIOLOGICAL: MEDI-524 (Numax-TM)|BIOLOGICAL: MEDI-524 (Numax-TM)|BIOLOGICAL: MEDI-524 (Numax-TM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of De-Stress & Happy Gut Powder for Stress and Indigestion in Adults.
Status: NOT_YET_RECRUITING
Conditions: Stress|Dyspepsia|Indigestion
Interventions: OTHER: De-stress & happy gut powder-U001|OTHER: De-Stress & Happy Gut powder-I001|OTHER: Placebo Powder 001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Slim Sheath 22F Holmium Laser Enucleation of the Prostate (HoLEP) vs 26 F Sheath HoLEP for BPH: RCT
Status: RECRUITING
Conditions: Benign Prostatic Hyperplasia
Interventions: DEVICE: 22F Sheath Size|DEVICE: 26F Sheath Size
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Single Rising Oral Doses of BI 137882 in Healthy Male Volunteers
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: BI 137882|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Hypertensive Injury to the Brain by Intensive Treatment in IntraCerebral Haemorrhage (PROHIBIT-ICH)
Status: UNKNOWN
Conditions: Intracerebral Hemorrhage
Interventions: DEVICE: A&D BP Digital Blood Pressure Monitor (UA-767PBT-Ci) CE Declaration UA-767PBT-Ci
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Intervention Study of Compound Silymarin in Patients With Non-alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: Silibinin extract, mixed power of pueraria, schisandra and salvia miltiorrhiza|DIETARY_SUPPLEMENT: Silibinin extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Micronutrient-supplemented Milk Study in Women of Childbearing Age
Status: COMPLETED
Conditions: Increase the Concentration of Folic Acid in Women of Childbearing Age
Interventions: DIETARY_SUPPLEMENT: ANMUM Materna|DIETARY_SUPPLEMENT: Control (milk powder)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: N-Acetylcysteine for Pediatric Trichotillomania
Status: COMPLETED
Conditions: Trichotillomania|Hair Pulling
Interventions: DRUG: N-Acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of New Phenotypes of Patients With Spinal Muscular Atrophy Treated With SMN Restoring Therapy
Status: RECRUITING
Conditions: Spinal Muscular Atrophy
Interventions: OTHER: evaluation of muscle function|OTHER: First-line cognitive assessment|OTHER: second-line cognitive assessment|OTHER: Cardiac evaluation|RADIATION: MRI|OTHER: Assessment of activity and muscle fatigue|OTHER: Assessment of bulbar function|OTHER: Evaluation of body composition and metabolism|OTHER: Questionnaires|BIOLOGICAL: Biocollection|OTHER: Skinfold measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Intraoperative Lidocaine Infusion on Intraoperative Isoflurane Requirements
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: sodium chloride solution|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Trial to Evaluate the Safety and Immunogenicity of a Modified Vaccinia Ankara (MVA)-Based Anti-Cytomegalovirus (CMV) Vaccine (Triplex®)
Status: ACTIVE_NOT_RECRUITING
Conditions: Cytomegalovirus Infections|HIV Infections|Vaccine
Interventions: BIOLOGICAL: CMV-MVA Triplex|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Radiation-Enhanced Allogeneic Cell Therapy for Progressive Hematologic Malignancy After Allogeneic Hematopoietic Stem Cell Transplantation
Status: TERMINATED
Conditions: Hodgkin's Lymphoma|Non-Hodgkin's Lymphoma|Chronic Lymphocytic Leukemias|Multiple Myeloma With Plasmacytoma
Interventions: PROCEDURE: Single fraction radiation|BIOLOGICAL: Donor Lymphocyte Infusion (DLI)|PROCEDURE: Apheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of rTMS and tDCS Treatment on Brain Function, Craving and Relapse Prevention
Status: WITHDRAWN
Conditions: Addiction
Interventions: DEVICE: Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparing Different Delivery Systems of Continuous Positive Airway Pressure in Neonates
Status: WITHDRAWN
Conditions: Prematurity|Respiratory Distress Syndrome
Interventions: DEVICE: RAM cannula ventilator CPAP|DEVICE: Occlusive interface bubble CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: WP2 Passive Case Detection
Status: COMPLETED
Conditions: African Trypanosomiases|West African; Trypanosomiasis|Sleeping Sickness; West African|Trypanosoma Brucei Gambiense; Infection
Interventions: DIAGNOSTIC_TEST: Rapid diagnostic test (RDT)|DIAGNOSTIC_TEST: Serological and molecular tests on DBS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nilotinib-Chemotherapy in CML Myeloid BP or Bcr-abl(+) AML
Status: UNKNOWN
Conditions: Chronic Myeloid Leukemia in Myeloid Blast Crisis|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: Nilotinib+AD induction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First In Human Study With ABBV-CLS-579 When Given Alone and In Combination In Participants With Locally Advanced Or Metastatic Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors Cancer
Interventions: DRUG: ABBV-CLS-579|DRUG: PD-1 inhibitor|DRUG: VEGFR TKI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Injections of Ranibizumab With Deferred Laser Grid Laser Photocoagulation for Treatment of Diabetic Macular Edema With Visual Impairment
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computerized Tight Glycemic Control in Cardiac Surgery
Status: COMPLETED
Conditions: Hyperglycemia
Interventions: DEVICE: Space GlucoseControl System, B. Braun, Melsungen, Germany|OTHER: Conventional therapy with a fixed insulin dosing scheme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Acute and Long-term Clinical Outcome of Self- Expandable Stent in Complex Proximal Superficial Femoral Artery Lesions Involving the Femoral Bifurcation
Status: NOT_YET_RECRUITING
Conditions: Common Femoral Artery Occlusive Disease
Interventions: PROCEDURE: endovascular treatment|PROCEDURE: endovascular treatment|PROCEDURE: endovascular treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunogenicity of Heterologous Versus Homologous Prime Boost Schedule With mRNA and Inactivated COVID-19 Vaccines
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: CoronaVac/CoronaVac|BIOLOGICAL: CoronaVac/BNT162b2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Using an Ergonomic Chinrest With or Without Shoulder Rest During Violin Playing: a Feasibility Study
Status: COMPLETED
Conditions: Ergonomics
Interventions: DEVICE: Ergonomic chinrest|DEVICE: Ergonomic chinrest used with a low Super Kun shoulder rest
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Safety, Tolerance and Pharmacokinetics Study of Compound Edaravone Injection
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Group 1: Compound Edaravone/Placebo Injection|DRUG: Group 2: Compound Edaravone/Placebo Injection|DRUG: Group 3: Compound Edaravone/Placebo Injection|DRUG: Group 4: Compound Edaravone/Placebo Injection|DRUG: Group 5: Compound Edaravone/Placebo Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pilot Randomized Controlled Trial for Hand Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Hand Osteoarthritis
Interventions: DEVICE: Hand orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT