pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Optimal Dosage of Remifentanil for Vertebroplasty
Status: NOT_YET_RECRUITING
Conditions: Remifentanil|Analgesia
Interventions: DRUG: Initial remifentanil effect-site concentration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ventilation Distribution Between Tidal Volume 6ml/kgBW and 10ml/kgBW
Status: COMPLETED
Conditions: Laparoscopic Nephrectomy
Interventions: PROCEDURE: Tidal volume 6 ml/kgBW|PROCEDURE: Tidal volume 10 ml/kgBW
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mobile Communication Technology for Adolescents With Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: GlucoPak|DEVICE: Cell Phone|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Endoscopic Stenting Across the Papilla Versus the Leak Site to Treat Bile Leak
Status: ENROLLING_BY_INVITATION
Conditions: Bile Leak
Interventions: PROCEDURE: Transpapillary Stent|PROCEDURE: Stent across bile leak
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Chemoimmunotherapy With Epratuzumab in Relapsed Acute Lymphoblastic Leukemia (ALL)
Status: COMPLETED
Conditions: Recurrent Childhood Acute Lymphoblastic Leukemia
Interventions: DRUG: L-asparaginase|DRUG: doxorubicin hydrochloride|DRUG: therapeutic hydrocortisone|DRUG: vincristine sulfate|BIOLOGICAL: epratuzumab|DRUG: cytarabine|DRUG: prednisone|DRUG: pegaspargase|DRUG: dexrazoxane hydrochloride|DRUG: methotrexate|DRUG: etoposide|DRUG: cyclophosphamide|DRUG: leucovorin calcium|BIOLOGICAL: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AflacLL1901 (CHOA-AML)
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|AML, Childhood
Interventions: DRUG: Cytarabine|DRUG: Daunorubicin|DRUG: Erwinase|DRUG: Etoposide|DRUG: Gemtuzumab ozogamicin|PROCEDURE: Stem cell transplantation (SCT)|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Riluzole Augmentation Pilot in Depression (RAPID) Trial
Status: TERMINATED
Conditions: Major Depressive Disorder
Interventions: DRUG: Riluzole|DRUG: Sertraline|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modulation Of The Tumour Microenvironment Using Either Vascular Disrupting Agents or STAT3 Inhibition in Order to Synergise With PD1 Inhibition in Microsatellite Stable, Refractory Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Nivolumab 10 MG/ML|DRUG: BNC 105|DRUG: BBI608
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevacid vs Lifestyle Modifications for the Treatment of LPR
Status: UNKNOWN
Conditions: Laryngopharyngeal Reflux
Interventions: DRUG: Prevacid 30mg BID|BEHAVIORAL: Lifestyle changes of exercise and diet changes for weight loss and avoidance of reflux inducing foods.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Fluzone® Influenza Virus Vaccines 2012-2013 Formulation Among Adults.
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza Virus Vaccine: Fluzone® 2012-2013 Formulation|BIOLOGICAL: Influenza Virus Vaccine: Fluzone® Intradermal 2012-2013 Formulation|BIOLOGICAL: Influenza Virus Vaccine: Fluzone® 2012-2013 Formulation|BIOLOGICAL: Influenza Virus Vaccine: Fluzone® High-Dose 2012-2013 Formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Health At Every Size and Acceptance and Commitment Therapy vs. Behavioral Weight Loss for Obesity and Depression in Women
Status: COMPLETED
Conditions: Depression|Obesity
Interventions: BEHAVIORAL: Accept Yourself!|BEHAVIORAL: Weight Watchers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abciximab for Prevention of Stroke Recurrence Before Endarterectomy in Symptomatic Carotid Stenosis
Status: TERMINATED
Conditions: Stroke|Stenosis
Interventions: DRUG: Abciximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and ML Training Investigation of the Senseye DT for Diagnosis of Adults With PTSD
Status: RECRUITING
Conditions: PTSD|Generalized Anxiety Disorder|Major Depressive Disorder
Interventions: DIAGNOSTIC_TEST: CAPS-5-R|DIAGNOSTIC_TEST: Senseye DT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gefitinib in Treating Patients With Metastatic Breast Cancer That Has Progressed After Antiestrogen and Nonsteroidal Aromatase Inhibitor Therapy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NEUROprotection Via optimizINg Cerebral Blood Flow afTer cArdiaC arresT (NEURO-INTACT) Study
Status: RECRUITING
Conditions: Out-Of-Hospital Cardiac Arrest (OHCA)
Interventions: OTHER: Individualized blood pressure strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NovaLign Intramedullary Fixation System (IFS) for the Treatment of Humeral Fractures
Status: UNKNOWN
Conditions: Fracture
Interventions: DEVICE: NovaLign Intramedullary Fixation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-up of Patients With Multiple Myeloma in the West-Occitanie Region "Living With a Myeloma in West-Occitanie"
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: OTHER: quality of life questionnaires (EORTC QLQ-C30 ; EORTC QLQMY20 ; EQ-5D-5L ; Cohen's stress scale)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Two Different Modes of Ventilation in Pretem Neonates Bilevel VG and PRVC
Status: COMPLETED
Conditions: Newborn Morbidity|Respiratory Failure|Bronchopulmonary Dysplasia|Mechanical Ventilation Complication
Interventions: DEVICE: GE ventilator with two different modes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Augmenting Exposure Therapy With an N-Methyl-D-Aspartate (NMDA) Agonist for Panic Disorder
Status: COMPLETED
Conditions: Panic Disorder
Interventions: BEHAVIORAL: Cognitive behavioral therapy|DRUG: D-cycloserine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Methadone and Hydromorphone For Spinal Surgery
Status: COMPLETED
Conditions: Hydromorphone Use|Acute Postoperative Pain|Patient Satisfaction|Chronic Persistent Surgical Pain
Interventions: DRUG: Methadone|DRUG: Hydromorphone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of Quadruple Therapy Zinc, Quercetin, Bromelain and Vitamin C on the Clinical Outcomes of Patients Infected With COVID-19
Status: UNKNOWN
Conditions: Covid-19
Interventions: DRUG: Quercetin|DIETARY_SUPPLEMENT: bromelain|DRUG: Zinc|DRUG: Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Designed to Compare the Safety and Pharmacokinetics of Intravenously Administered Superoxide Dismutase Mimetic GC4711 and GC4419 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers|Healthy
Interventions: DRUG: GC4711 30 mg IV|DRUG: GC4711 50 mg IV|DRUG: GC4419 45 mg IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Vibrant Capsule vs. Placebo for the Treatment of Chronic Idiopathic Constipation
Status: COMPLETED
Conditions: Chronic Idiopathic Constipation
Interventions: DEVICE: Vibrating capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Is Bio-adrenomedullin (Bio-ADM) a Prognostic Factor in Patients With COVID-19 Treated in the ICU?
Status: TERMINATED
Conditions: Covid19
Interventions: DEVICE: IB10 sphingotest® bio-ADM® apparatus (Sphingotec GmbH, Hennigsdorf, Germany)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nitric Oxide Therapy for Acute Chest Syndrome in Sickle Cell Disease Children
Status: COMPLETED
Conditions: Acute Chest Syndrome|Sickle Cell Disease
Interventions: DRUG: Nitric oxide by inhalation INOMAX|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety and Efficacy of Belantamab for the Treatment of Multiple Myeloma When Used as Monotherapy and in Combination Treatments
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Bela|DRUG: Belamaf|DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Infectivity, Safety, and Immunogenicity of a Recombinant Live-Attenuated Respiratory Syncytial Virus Vaccine in RSV-Seronegative Infants and Children 6 to 24 Months of Age
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSV LID ΔM2-2 1030s vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of a Diabetes Self-Management Education Program for Non-Intensified Insulin Therapy in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: MEDIAS 2 CT|BEHAVIORAL: Current CT program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjects (CL-009)
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: PA-824 200mg|DRUG: PA-824 50mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bendamustine Hydrochloride in Combination With Rituximab in Patients With Relapsed Refractory Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Bendamustine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interscalene Block Versus Superior Trunk Block
Status: COMPLETED
Conditions: Joint Disease|Pain|Pain, Acute|Pain, Chronic
Interventions: DRUG: Bupivacaine|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2B Dose Ranging Study of Locteron Plus Ribavirin to Treat HCV
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: ribavirin|DRUG: Locteron™ (controlled-release interferon alpha 2b)|DRUG: PEG-Intron™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VYxeoS Liposomal Italian Observational Study iN the Real Practice
Status: RECRUITING
Conditions: Acute Myeloid Leukemia (AML)|Acute Myeloid Leukemia With Myelodysplasia-Related Changes|Therapy-Related Acute Myeloid Leukemia
Interventions: DRUG: Vyxeos liposomal
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of the Self-Care Support Program on Women With Endometriosis
Status: NOT_YET_RECRUITING
Conditions: Endometriosis|Quality of Life|Depression|Anxiety|Stress
Interventions: BEHAVIORAL: Endometriosis Self-care Support Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Topical Tranexamic Acid Application in Rhinoplasty
Status: COMPLETED
Conditions: Ecchymosis; Eyelid|Edema|Rhinoplasty
Interventions: DRUG: Tranexamic acid|OTHER: Isotonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of the Care Bundle to be Applied to Obesity Surgery Patients on Surgical Site Infection and Patient Comfort
Status: RECRUITING
Conditions: Bariatric Surgery Candidate
Interventions: OTHER: Surgical Site Infection (SSI) prevention package
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CoolLoop Paroxysmal Atrial Fibrillation
Status: TERMINATED
Conditions: Atrial Fibrillation (Paroxysmal)|Arrhythmias, Cardiac|Cardiovascular Diseases|Heart Diseases|Pathologic Processes
Interventions: DEVICE: CoolLoop®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhalational Anesthesia vs TIVA in Endoscopic Tympanoplasty
Status: RECRUITING
Conditions: Perforated Eardrum
Interventions: DRUG: Isoflurane Inhalant Product|DRUG: Sevoflurane inhalant product|DRUG: Propofol injection|DRUG: Remifentanil Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: An Extension to Study AZA PH GL 2003 CL 001 Allowing for Continuation of Azacitidine Treatment in Patients With Myelodysplastic Syndromes (MDS)
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study to Assess Delivery of LMN-201 Components Via Enteric Capsules in the Gut of Individuals With Ostomies
Status: COMPLETED
Conditions: C. Diff. Infections
Interventions: BIOLOGICAL: LMN-201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pringle's Maneuver Versus Selective Hepatic Vascular Exclusion in Hepatectomy
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Selective Hepatic Vascular Exclusion|PROCEDURE: Pringle's Maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gefitinib in Treating Patients With Progressive Metastatic Neuroendocrine Tumors
Status: COMPLETED
Conditions: Gastrinoma|Glucagonoma|Insulinoma|Metastatic Gastrointestinal Carcinoid Tumor|Pancreatic Polypeptide Tumor|Recurrent Gastrointestinal Carcinoid Tumor|Recurrent Islet Cell Carcinoma|Somatostatinoma|WDHA Syndrome
Interventions: DRUG: gefitinib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SBRT and LDRT Combined With PD-1 Antibody and Chemotherapy in r/m Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: RADIATION: SBRT|RADIATION: Low-dose Radiotherapy (LDRT)|DRUG: Toripalimab|DRUG: Gemcitabine|DRUG: Cisplatin|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Electrical Stimulation on Palatal Wound Healing.
Status: UNKNOWN
Conditions: Palatal Wound
Interventions: PROCEDURE: Free Gingival Graft|DEVICE: SHAM Electric stimulation|DEVICE: Electric Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stamford Group Family Nurture Intervention
Status: COMPLETED
Conditions: Behavior Problem|Developmental Delay|Emotional Disturbances|Family Conflict
Interventions: BEHAVIORAL: Nutrition and Play Intervention|BEHAVIORAL: Family Nurture Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Rhinopharyngeal Retrograde Clearance is Effective to Adequate Upper Airways Function in Adults
Status: COMPLETED
Conditions: Nasal Obstruction|Exposure to Pollution
Interventions: OTHER: rhinopharyngeal retrograde clearance (RRC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Three Doses of T-20 When Given in Combination With Abacavir, Amprenavir, Ritonavir, and Efavirenz to HIV-Infected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Enfuvirtide|DRUG: Ritonavir|DRUG: Abacavir sulfate|DRUG: Amprenavir|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Validation Use of Implants and Abutments With Biologically Oriented Preparation Technique
Status: COMPLETED
Conditions: Dental Implant-Abutment Design
Interventions: PROCEDURE: Implant surgery and restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Nimotuzumab Concurrent With Chemoradiotherapy for Esophageal Cancer Patients
Status: RECRUITING
Conditions: Esophageal Cancer|Nimotuzumab|Chemoradiotherapy|Chemotherapy|Immunotherapy
Interventions: COMBINATION_PRODUCT: Nimotuzumab with chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine GSK1437173A in Adults With a Prior Episode of Herpes Zoster
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Herpes Zoster vaccine (GSK1437173A)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of Satralizumab in Participants With Neuromyelitis Optica Spectrum Disorder (NMOSD)
Status: COMPLETED
Conditions: Neuromyelitis Optica Spectrum Disorder
Interventions: DRUG: satralizumab|DRUG: azathioprine (AZA)|DRUG: mycophenolate mofetil (MMF)|DRUG: oral corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for Oral Formula of Vanillin and Wheat Germ Oil for Treatment of Mild and Moderate COVID-19 Viral Disease
Status: UNKNOWN
Conditions: Mild-to-moderate COVID-19
Interventions: DRUG: Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Febuxostat in Hyperuricemia Among Hemodialysis Patients
Status: COMPLETED
Conditions: Hyperuricemia|Hemodialysis Complication
Interventions: DRUG: Febuxostat 40 milligramsTablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer
Status: RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Inavolisib|DRUG: Phesgo|DRUG: Placebo|DRUG: Taxane-based Chemotherapy|DRUG: Optional Endocrine Therapy of Investigator's Choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Bilateral Superficial Cervical Plexus Block vs. Local Infiltration of Lidocaine 2% in Tracheostomy Procedure
Status: COMPLETED
Conditions: Tracheostomy
Interventions: PROCEDURE: Analgesic Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Protective Effect of Low-dose Aspirin on Renal Function in Patients With Early Diabetic Nephropathy
Status: NOT_YET_RECRUITING
Conditions: Diabetic Nephropathy Type 2
Interventions: DRUG: Acetylsalicylic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: REALIsM-HF Pilot Study
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: AVIVO Mobile Patient Management (MPM) System|DEVICE: VitalPatch biosensor|DEVICE: DynaPort Move Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Enhance Study: Evaluation of Accuracy and Safety of the Eversense CGM System With Enhanced Features
Status: RECRUITING
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DEVICE: Continuous Glucose Monitoring System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MT2014-14 IT-MSC for Advanced Cerebral Adrenoleukodystrophy (cALD)
Status: WITHDRAWN
Conditions: Cerebral Adrenoleukodystrophy
Interventions: BIOLOGICAL: Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of ALKS 9072 (Also Known as Aripiprazole Lauroxil, ALKS 9070, or ARISTADA) in Subjects With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: ALKS 9072|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and Radiation Therapy or Ipilimumab as Adjuvant Therapy in Treating Patients With Merkel Cell Cancer
Status: COMPLETED
Conditions: Merkel Cell Carcinoma|Pathologic Stage IIIA Merkel Cell Carcinoma AJCC v8|Pathologic Stage IIIB Merkel Cell Carcinoma AJCC v8
Interventions: BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Cholecystectomy for Acute Cholecystitis After 72 Hours of Symptoms
Status: TERMINATED
Conditions: Acute Cholecystitis|Cholecystectomy
Interventions: PROCEDURE: Laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postprandial Muscle Protein Synthesis Following Wheat Protein Ingestion in Vivo in Humans
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: protein type and amount
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: AZD5069 Neutrophil Function Study
Status: COMPLETED
Conditions: Chemokine Receptor 2 (CXCR2) Antagonist
Interventions: DRUG: 100 mg (50 mg x 2) AZD5069|DRUG: 100 mg Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Preoperative and Post Operative Misoprostol Administration on Intraoperative Blood Loss and Postpartum Hemorrhage in CS
Status: COMPLETED
Conditions: Post Partum Hemorrhage
Interventions: PROCEDURE: cesarean section|DRUG: Misoprostol|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Haemostasis Management of Abdominal Aortic Procedures
Status: UNKNOWN
Conditions: Abdominal Aortic Aneurism|Abdominal Aortic Rupture|Perioperative/Postoperative Complications|Surgical Blood Loss
Interventions: DIAGNOSTIC_TEST: Coagulation tests
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recovery From 50 Eccentric Biceps Curls in Young, Untrained Men and Women
Status: COMPLETED
Conditions: Recovery|Muscle Damage|Muscle Stiffness|Cell Structure Alteration|Calcium Cycling
Interventions: OTHER: Eccentric biceps curls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: De-Implementing Fall Prevention Alarms in Hospitals
Status: RECRUITING
Conditions: Accidental Fall|Patient Safety|Hospital Acquired Condition|Clinical Alarms|Mentoring
Interventions: OTHER: High Intensity Coaching|OTHER: Low Intensity Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Telocytes in Umbilical Cord of Patients With and Without Pre-eclampsia
Status: UNKNOWN
Conditions: Telocytes in Umbilical Cord of Pregnancies Complicated by Chronic Hypertension, Gestational Hypertension and Preeclampsia
Interventions: OTHER: Placental and Umbilical cord biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics of the Fixed Dose Combination of Tiotropium Plus BI 54903 Versus the Combination of the Monoproducts of Tiotropium and BI 54903 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tiotropium|DRUG: Tiotropium|DRUG: BI 54903|DRUG: BI 54903
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of DF9001 in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor, Adult
Interventions: DRUG: DF9001|DRUG: pembrolizumab|DRUG: KEYTRUDA®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced-dosed Rivaroxaban in the Long-term Prevention of Recurrent Symptomatic VTE(Venous Thromboembolism)
Status: COMPLETED
Conditions: Pulmonary Embolism|Thromboembolism|Thrombosis|Venous Thrombosis|Venous Thromboembolism
Interventions: DRUG: BAY 59-7939|DRUG: BAY 59-7939|DRUG: ASA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of SHR0302 in Patients With Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: SHR0302|DRUG: SHR0302 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing an Innovative Biomarker: Expression of HIF-1α and Its Isoforms in the Blood and Skin Tissue of Major Burns
Status: UNKNOWN
Conditions: Burn Injuries
Interventions: OTHER: Blood drawn
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mobile Technologies Extending Reach of Primary Care for Substance Use Disorders
Status: RECRUITING
Conditions: Substance-Related Disorders
Interventions: DEVICE: SBIRT/eIntervention for those with moderate risk drug or alcohol use|DEVICE: SBIRT/eIntervention those assessed with high risk.|OTHER: SBIRT/TAU for those with moderate risk drug or alcohol use|OTHER: SBIRT/TAU for those assessed with high risk.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Using an Adjustable Compression Garment for Secondary Upper Limb Lymphoedema
Status: UNKNOWN
Conditions: Lymphedema of Upper Arm
Interventions: OTHER: Manual lymph drainage.|PROCEDURE: Coban compression bandage..|DEVICE: Adjustable Compression Sleeve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abdominoplasty With Ventral Hernia Repair Versus Hernioplasty .
Status: NOT_YET_RECRUITING
Conditions: Abdominal Hernia
Interventions: PROCEDURE: Abdominoplasty with ventral hernia repair versus ventral hernioplasty.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Herpetic Eye Disease Study (HEDS) II
Status: COMPLETED
Conditions: Keratitis, Herpetic|Ocular Herpes Simplex|Herpes Simplex
Interventions: BEHAVIORAL: Stress|DRUG: Acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Two Irbesartan in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Therapeutic Equivalency
Interventions: DRUG: Tested Irbesartan Tablet|DRUG: Reference Irbesartan Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Behavioral Exercise Therapy and Multidisciplinary Rehabilitation for Chronic Non-specific Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: BEHAVIORAL: Behavioral Medical Rehabilitation plus behavioral exercise therapy|BEHAVIORAL: Usual Behavioral Medical Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: KIR Favorable Mismatched Haplo Transplant and KIR Polymorphism in ALL/AML/MDS Allo-HCT Children
Status: ENROLLING_BY_INVITATION
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: DEVICE: CliniMacs TCR alpha-beta-Biotin system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections
Status: COMPLETED
Conditions: Abscess|Wound Infection|Surgical Site Infection|Cellulitis
Interventions: DRUG: IV Dalbavancin|DRUG: Vancomycin/Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-190)(COMPLETED)
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: MK0966, rofecoxib|DRUG: Comparator: valdecoxib, placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Assess The Effect Of PF-03526299 On Lung Function Following An Allergen Challenge In Asthmatic Subjects
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: PF-03526299|DRUG: Placebo|DRUG: Fluticasone propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sevoflurane for Treatment-Resistant Depression
Status: UNKNOWN
Conditions: Depressive Disorder, Treatment-Resistant|Depressive Disorder, Major
Interventions: DRUG: Sevoflurane|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of Functional MRI (Magnetic Resonance Imagery) (in Patients Suffering From Hepatocellular Carcinoma and Treated With Yttrium
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: OTHER: Additional RMIs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Measuring rTMS-induced Neuroplasticity With EEG Steady-state Visual-evoked Potentials
Status: ENROLLING_BY_INVITATION
Conditions: Visual Cortical Plasticity|Repetitive Transcranial Magnetic Stimulation|Visual Attention
Interventions: DEVICE: repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fondaparinux for the Treatment of Heparin-Induced Thrombocytopenia (HIT)
Status: TERMINATED
Conditions: Heparin-Induced Thrombocytopenia
Interventions: DRUG: fondaparinux|DRUG: warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Time-Restricted Eating in Patients With Metabolic Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Metabolic Syndrome|Pre-Diabetes
Interventions: BEHAVIORAL: Time Restricted Eating + Standard of Care|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone for PENG Block in Total Hip Arthroplasty
Status: NOT_YET_RECRUITING
Conditions: Hip Osteoarthritis|Hip Arthropathy|Hip Pain Chronic
Interventions: DRUG: Ropivacaine 0.2% Injectable Solution|DRUG: Ropivacaine 0.2% Injectable Solution + 4mg Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BEKINDA (Ondansetron 24 mg Bimodal Release Tablets) for Vomiting Due to Presumed Acute Gastroenteritis or Gastritis
Status: COMPLETED
Conditions: Gastroenteritis|Gastritis
Interventions: DRUG: RHB-102|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of TCA Effect on Varicella Atrophic Scars
Status: UNKNOWN
Conditions: Atrophic Varicella Scar
Interventions: DRUG: 70% trichloroacetic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Response to Toll-Like Receptor 9-Agonist Adjuvanted Pneumococcal Vaccination in HIV Infected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Pneumococcal vaccines + CPG 7909|BIOLOGICAL: Pneumococcal vaccines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment Effect of Saxagliptin Compared With Placebo in Patients With Type 2 Diabetes and Renal Impairment
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Saxagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Evaluation of Mesenchymal Stem Cells for the Treatment of Patients With Respiratory Distress Due to COVID-19
Status: COMPLETED
Conditions: COVID-19|SARS-CoV 2|Adult Respiratory Distress Syndrome
Interventions: DRUG: XCEL-UMC-BETA|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CONCEPT: A 1-Year Comparison Of A Stable Dose Of SERETIDE® Inhaler With An Adjustable Maintenance Dose Of SYMBICORT® Inhaler. SERETIDE® Inhaler is a Trademark of GSK Group of Companies. SYMBICORT® Inhaler is a Trademark of Astra Zeneca.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Salmeterol/fluticasone propionate or formoterol/budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transfer Factor Efficacy in the Management of Cirrhosis-associated Immune Dysfunction
Status: WITHDRAWN
Conditions: Cirrhosis|Liver Failure
Interventions: DRUG: Human derived Transfer factor|DRUG: Aqua pro injectione 4ml ampules for subcutaneous injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Synbiotic to Attenuate Resorption of the Skeleton
Status: NOT_YET_RECRUITING
Conditions: Osteoporosis|Inflammation|Aging
Interventions: OTHER: SBD111 medical food|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Thrombolytic Therapy Versus Surgery for Obstructive Prosthetic Valve Thrombosis
Status: UNKNOWN
Conditions: Obstructive Thrombus
Interventions: DRUG: Thrombolytic Therapy|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of a Pseudoallergen-Free Diet in the Treatment of Chronic Idiopathic Urticaria and/or Angioedema
Status: UNKNOWN
Conditions: Urticaria|Angioedema
Interventions: BEHAVIORAL: Dietary Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Effectiveness Study of CELLBOOSTER® Lift (Stabilized Booster Complex Using CHAC Technology)
Status: COMPLETED
Conditions: Skin Fold|Skin Laxity|Skin Texture Disorder|Skin Depression|Skin Dryness|Hyperpigmentation|Atrophic Scar|Striae Distensae|Oxidative Stress
Interventions: DEVICE: (D0) Intradermal injection - micropapula technique|DEVICE: (D14) Intradermal injection - micropapula technique|DEVICE: (D28) Intradermal injection - micropapula technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UNAIR Inactivated COVID-19 Vaccine as Heterologue Booster (Immunobridging Study)
Status: UNKNOWN
Conditions: COVID-19 Pandemic|COVID-19 Vaccines
Interventions: BIOLOGICAL: Vaksin Merah Putih - UA SARS-CoV-2 (Vero Cell Inactivated) 5 µg|BIOLOGICAL: CoronaVac Biofarma COVID-1 9 Vaccine 3 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention of Obesity in Women Via Estradiol Regulation
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: leuprolide acetate|DRUG: Estradiol Transdermal|BEHAVIORAL: progressive resistance exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Seminal Levels of PGK2 and ACRV1 as Predictors of Micro-TESE Results in NOA
Status: NOT_YET_RECRUITING
Conditions: Male Infertility Due to Azoospermia
Interventions: DIAGNOSTIC_TEST: Measurement of PGK2 and ACRV1 levels in the semen of infertile males undergoing testicular sperm extraction (TESE).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Docetaxel in Locally Advanced Gastric Adenocarcinoma
Status: COMPLETED
Conditions: Stomach Neoplasms
Interventions: DRUG: Docetaxel|DRUG: Cisplatin|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Functional Therapy for Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain|Back Pain|Pain|Signs and Symptoms|Neuromuscular Manifestations
Interventions: BEHAVIORAL: Cognitive Functional Therapy|OTHER: Manual Therapy and Motor Control Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VIT45 Versus Oral Iron in the Treatment of Anemia in Non-Dialysis Dependent Chronic Kidney Disease
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Ferrous Sulfate tablets|DRUG: Ferric Carboxymaltose (FCM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diclofenac Phonophoresis Versus High Power Pain Threshold Ultrasound on Patients With Neck Pain
Status: UNKNOWN
Conditions: Neck Pain
Interventions: OTHER: diclofenac phonophoresis|OTHER: high power pain threshold ultrasound|OTHER: conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Positional Device on the Obstructive Sleep Apnea in Patients With Ischemic Stroke
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Brain Ischemia
Interventions: DEVICE: positional device|DEVICE: lumbar corset
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Photic and Non-photic Time Cues in Resetting Circadian Rhythms
Status: RECRUITING
Conditions: Light Exposure|Meal Timing
Interventions: BEHAVIORAL: Bright Light|BEHAVIORAL: Time-restricted eating|BEHAVIORAL: Dim light|BEHAVIORAL: 12-h meal window
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of EGFRBi Armed Fresh PBMC in Metastatic or Unresectable Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Pancreas Cancer|Pancreatic Cancer
Interventions: DRUG: EGFR FPBMC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of CRx-191 to Assess Activity in Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: mometasone furoate|DRUG: nortriptyline HCl|DRUG: Vehicle (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A proof-of Concept, Randomized 3-month Study to Evaluate the Effects of Three Contraceptive Intrauterine Systems Delivering Copper and a Daily Dose of 5, 20 or 40 μg of Ulipristal Acetate (UPA)
Status: UNKNOWN
Conditions: Contraception
Interventions: DRUG: Ulipristal Acetate IUS delivering Cu and 5μg|DRUG: Ulipristal Acetate IUS delivering Cu and 20μg|DRUG: Ulipristal Acetate IUS delivering Cu and 40μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Liposomal Annamycin for the Treatment of Subjects With Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Liposomal Annamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetes Diagnosis, Management, Prevention and Education in Guinea-Bissau
Status: RECRUITING
Conditions: Diabetes Mellitus|BCG Vaccination Reaction
Interventions: BIOLOGICAL: BCG vaccine (two doses, 4 weeks apart)|BIOLOGICAL: Saline placebo (Two doses, 4 weeks apart)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Rociletinib Genomic Landscape in Non-small Cell Lung Cancer (NSCLC)
Status: WITHDRAWN
Conditions: Carcinoma, Non-Small-Cell Lung|Non-Small Cell Lung Cancer|Nonsmall Cell Lung Cancer
Interventions: DRUG: Rociletinib|PROCEDURE: Biopsy|PROCEDURE: Blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a New Generation of Orthopedic Brace for Treating Adolescent Idiopathic Scoliosis by Using Growth Modulation
Status: UNKNOWN
Conditions: Scoliosis|Adolescent Idiopathic Scoliosis
Interventions: DEVICE: Test brace versus control brace: Immediate correction|DEVICE: Test brace versus control brace: Long-term correction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of Imiquimod Creams in the Treatment of External Genital Warts
Status: COMPLETED
Conditions: Genital Warts
Interventions: DRUG: Imiquimod|DRUG: 3.75% imiquimod cream|DRUG: placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT