pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Next Generation Rocklatan
Status: NOT_YET_RECRUITING
Conditions: Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: AR-17043 Ophthalmic Solution|DRUG: PG043 Ophthalmic Solution|DRUG: Latanoprost 0.005% Ophthalmic Solution|DRUG: Netarsudil 0.02% Ophthalmic Solution|DRUG: Netarsudil 0.02%/Latanoprost 0.005% Ophthalmic Solution|DRUG: AR-17043 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Impact of Escitalopram on Quality of Life and Social Functionality in Patients With Major Depressive Disorder With Anxiety Symptom
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Cholangio-pancreatoscopy for the Diagnosis and the Treatment of Biliary and Pancreatic Diseases
Status: UNKNOWN
Conditions: Lesions of Biliary or Wirsung Ducts|Biliary Tract Diseases|Common Bile Duct Diseases|Pancreatic Duct Disorder
Interventions: PROCEDURE: cholangio-pancreatoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Biofeedback Gait Training by Target Biomechanical Parameters in the Early Recovery Period of Stroke
Status: RECRUITING
Conditions: Stroke|Biofeedback|Gait, Hemiplegic|Gait Training|Hemiparesis
Interventions: OTHER: Biofeedback gait training by biomechanical target parameter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ketamine vs. Active Placebo on Suicidal Ideation in Depressed Inpatients With Major Depressive Disorder or Bipolar Depression.
Status: COMPLETED
Conditions: Major Depressive Disorder|Bipolar I Disorder|Bipolar II Disorder|Bipolar Depression|Suicidal Ideation
Interventions: DRUG: Ketamine|DRUG: Midazolam|OTHER: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trichotillomania: Group Cognitive-Behavioral Therapy
Status: COMPLETED
Conditions: Trichotillomania
Interventions: BEHAVIORAL: Cognitive-behavioral therapy.|OTHER: Supportive therapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Whether Avenciguat Helps People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver) Who Had Bleeding in the Esophagus or Fluid Accumulation in the Belly
Status: TERMINATED
Conditions: Hypertension, Portal|Liver Cirrhosis
Interventions: DRUG: Placebo|DRUG: Avenciguat (BI 685509)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lung Deposition of Beclometasone Dipropionate/Formoterol Fumarate/Glycopyrronium Bromide Administered Via pMDI in Healthy, Asthmatic and COPD Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Asthma
Interventions: DRUG: Beclometasone dipropionate/Formoterol Fumarate/Glycopyrronium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eating Mindfully to Prevent Weight Regain
Status: RECRUITING
Conditions: Weight Loss|Weight Gain|Eating Behavior|Obesity|Bariatric Surgery Candidate
Interventions: BEHAVIORAL: Mindfulness Orientated Recovery Enhancement|BEHAVIORAL: Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Routine Versus Aggressive Upstream Rhythm Control for Prevention of Early Atrial Fibrillation in Heart Failure
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: OTHER: Upstream therapy|OTHER: Conventional rhythm control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Surgery Versus Robot Surgery for Right-side Colon Cancer: Short-term Outcome of a Randomised Clinical Trial
Status: COMPLETED
Conditions: Colon Cancer
Interventions: PROCEDURE: robot-assisted surgery|PROCEDURE: laparoscopic right-hemicolectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acupressure Versus Transcutaneous Electrical Nerve Stimulation on Pain and Quality of Life Intradialysis
Status: COMPLETED
Conditions: Hemodialysis Complication
Interventions: OTHER: Acupressure|DEVICE: Transcutaneous electrical nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Simvastatin in Relapsing Remitting Multiple Sclerosis (RRMS) Patients Using Avonex Compared to Placebo
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: simvastatin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Immunomodulatory Tyrosine Kinase Inhibitor in Patients With Locally Advanced or Metastatic Solid Tumors
Status: TERMINATED
Conditions: Advanced or Metastatic Solid Tumors
Interventions: DRUG: RXDX-106
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Study of Brain Amyloid imaGing in MEMENTO
Status: COMPLETED
Conditions: Alzheimer's Disease (AD) and Related Disorders
Interventions: DRUG: Flutemetamol (18F)|DRUG: Florbetapir (18F)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating the Role of Both PSMA and 64Cu-PET/CT Total Body in Patients With Locally Relapsed Prostate Cancer
Status: COMPLETED
Conditions: Prostate Neoplasms
Interventions: DEVICE: Pilot evaluation study on use PSMA and Cu-PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prevention of Maternal and Fetal Metabolic Complications With Diet and Nutraceutical Supplementation in Pregnant Women Affected by Gestational Diabetes: a Randomized, Double-blind Placebo Controlled Trial.
Status: TERMINATED
Conditions: Gestational Diabetes|Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: omega-3 fatty acids, anthocyanins and alpha-cyclodextrins|BEHAVIORAL: diet|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mobile Electrocardiogram Monitoring for Detecting Arrhythmias in Children
Status: RECRUITING
Conditions: Arrhythmias, Cardiac|Children, Only|Congenital Heart Disease|Sudden Cardiac Death|Diagnoses Disease
Interventions: DIAGNOSTIC_TEST: KARDIA Mobile ECG Monitoring (KMCM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Sibutramin-containing Drugs in Patient With Alimentary Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: metformin+sibutramine|DRUG: sibutramine+ microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Colchicine in Argentina to Prevent Restenosis
Status: UNKNOWN
Conditions: Coronary Artery Disease|Restenosis of Coronary Artery Stent|Atherosclerosis|Acute Coronary Syndrome
Interventions: DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptability and Efficacy of 'Fish Surimi Peptide' in Under Five Children Suffering From Moderate Acute Malnutrition
Status: COMPLETED
Conditions: Moderate Acute Malnutrition
Interventions: DIETARY_SUPPLEMENT: Fish surimi peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Phase I Study Of Human- Recombinant Bone Morphogenetic Protein 4 Administrated Via CED In GBM Patients
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: hrBMP4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of High-Dose Vitamin D in the Treatment of Complicated Severe Acute Malnutrition
Status: COMPLETED
Conditions: Severe Acute Malnutrition
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of AGA111 for Lumbar Interbody Fusion in Patients With Degenerative Disc Disease
Status: COMPLETED
Conditions: Degenerative Disc Disease
Interventions: DRUG: AGA111|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Bioavailability of Tislelizumab Via Subcutaneous Injection in First-Line Treatment of Participants With Advanced or Metastatic Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Tislelizumab IV|DRUG: Tislelizumab SC|DRUG: Histology-Based Chemotherapy Doublet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Circulating Tumor DNA to Personalize Duration of Consolidation Durvalumab
Status: RECRUITING
Conditions: NSCLC, Stage III
Interventions: DIAGNOSTIC_TEST: Signatera ctDNA test|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antipsychotics and Gene Expression in Soft Tissues
Status: COMPLETED
Conditions: Schizophrenia|Diabetes
Interventions: DRUG: olanzapine|DRUG: ziprasidone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Adjuvant Chemotherapy With Paclitaxel and Cisplatin in Lymph Node-Positive Adjuvant Chemotherapy in the Treatment of the Lymph Node Positive Thoracic Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: DRUG: paclitaxel; cisplatin|RADIATION: radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics on Health-related Quality of Life in College Students With Upper Respiratory Infections
Status: COMPLETED
Conditions: Upper Respiratory Infection
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effect of Nurse-led Supportive Care on Caregiver Burden and Well-being
Status: COMPLETED
Conditions: Nurse-led Supportive Care
Interventions: BEHAVIORAL: Nurse-led supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Diagnostic Efficacy of Mangoral in Participants With Focal Liver Lesions and Reduced Kidney Function
Status: COMPLETED
Conditions: Known or Suspected Focal Liver Lesions|Severe Renal Impairment
Interventions: DRUG: Mangoral
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: AlloStim® Immunotherapy Dosing Alone or in Combination With Cryoablation in Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic
Interventions: BIOLOGICAL: AlloStim|PROCEDURE: Cryoablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TACE/HAIC Combined With Lenvatinib and Sintilimab in Neoadjuvant Therapy for Intermediate-stage HCC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: TACE/HAIC|DRUG: Lenvatinib|DRUG: Sintilimab|PROCEDURE: liver resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Short Computer-based Emotion Recognition Training in Different Patient Groups
Status: UNKNOWN
Conditions: Autism Spectrum Disorder|Conduct Disorder
Interventions: BEHAVIORAL: Emotionen Verstehen und Ausdrücken (E.V.A.)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bio-equivalence Study
Status: COMPLETED
Conditions: Bioequivalence|Bioavailability
Interventions: DIETARY_SUPPLEMENT: MenaQ7 M-1500 capsules|DIETARY_SUPPLEMENT: Gnosis P-1000 capsules|DIETARY_SUPPLEMENT: Gnosis M-1500 capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study With Visonac Photodynamic Therapy (PDT)
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Visonac PDT (MAL PDT)|DRUG: Vehicle cream (placebo)|PROCEDURE: PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Depth of Neuromuscular Blockade and the Perioperative Conditions in Laparoscopic Surgery in Pediatric Population
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: DRUG: Rocuronium|DRUG: Cisatracurium|DRUG: Nonspecific Neuromuscular Blockade reversal|DRUG: Specific Neuromuscular Blockade reversal|DRUG: maintaining the depth of neuromuscular blockade - rocuronium|DRUG: maintaining the depth of neuromuscular blockade - cisatracurium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Radiation With Concomitant and Then Sequential Temozolomide in Malignant Glioma
Status: UNKNOWN
Conditions: Newly Diagnosed Supratentorial Malignant Glioma
Interventions: DRUG: Gliadel Wafer|DRUG: Temozolomide|PROCEDURE: Limited field radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Tidal Volume Ventilation Strategies on Fontan Flow and Hemodynamics
Status: COMPLETED
Conditions: Fontan Physiology
Interventions: OTHER: Small volume breath and fast breathing rate for 5 minutes|OTHER: Large volume breath and slow breathing rate for 5 minutes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Tacrolimus as Secondary Intervention vs. Continuation of Cyclosporine in Renal Transplant Patients With Chronic Renal Allograft Failure (CRAF)
Status: COMPLETED
Conditions: Renal Transplantation|Chronic Renal Allograft Failure
Interventions: DRUG: Tacrolimus|DRUG: Cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prolotherapy Intervention Effect in Patient With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Prolotherapy|DRUG: Sodium Hyaluronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Performance of a hsRDT Versus cRDT in Reactive Case Detection of Malaria Infections
Status: UNKNOWN
Conditions: Malaria Diagnosis|Malaria,Falciparum
Interventions: DIAGNOSTIC_TEST: hsRDT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Long-term Treatment Study of Certolizumab Pegol Without Coadministration of Methotrexate in Japanese Rheumatoid Arthritis (RA) Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Certolizumab pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical, Translational and Biomarker-Based Female Genital HPV Induced Dysplasia and Cancer Screening Study Using Cf-HPV-DNA Blood Tests
Status: UNKNOWN
Conditions: Cervical Dysplasia, Uterine|Vaginal Dysplasia|Vulvar Dysplasia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rituximab in Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Status: COMPLETED
Conditions: Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Interventions: DRUG: Rituximab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety in Patients With Primary IgA Nephropathy Who Have Completed Study Nef-301 (Nefigard-OLE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary IgA Nephropathy
Interventions: DRUG: Nefecon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Markers of Organ Congestion in Severe Acute Kidney Injury
Status: COMPLETED
Conditions: Acute Kidney Injury|Fluid Overload|Ultrasonography
Interventions: DIAGNOSTIC_TEST: Portal vein flow|DIAGNOSTIC_TEST: Intra-renal flow|DIAGNOSTIC_TEST: Hepatic vein flow|DIAGNOSTIC_TEST: Pulmonary B-lines|DIAGNOSTIC_TEST: Dimensions of the inferior vena cava|DIAGNOSTIC_TEST: Left ventricular function|DIAGNOSTIC_TEST: Right ventricular function
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Accuracy of the Red Reflex Test in the Pediatric Population
Status: COMPLETED
Conditions: Abnormal Vitreous Humor Morphology|Abnormal Choroid Morphology|Optic Nerve Diseases|Retinal Disease|Retinal Hemorrhage
Interventions: DIAGNOSTIC_TEST: Direct ophthalmoscope
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Sotagliflozin on Cardiovascular and Renal Events in Participants With Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk
Status: TERMINATED
Conditions: Heart Failure|Type 2 Diabetes Mellitus|Chronic Kidney Diseases
Interventions: DRUG: Sotagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Incretin on the Blood Pressure and Lipid in Patients With Overweight or Obese Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes|Overweight|Obesity|Masked Hypertension
Interventions: DRUG: "Liraglutide" and "Mitiglinide"|DRUG: "Metformin" and "Mitiglinide"|DRUG: "Mitiglinide"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Chiropractic Care and Children With Subclinical Spinal Pain
Status: COMPLETED
Conditions: Subclinical Spinal Pain
Interventions: OTHER: Chiropractic care|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MERS-CoV Infection tReated With A Combination of Lopinavir /Ritonavir and Interferon Beta-1b
Status: COMPLETED
Conditions: Middle East Respiratory Syndrome Coronavirus (MERS-CoV)
Interventions: DRUG: Combination of Lopinavir /Ritonavir and Interferon beta-1b|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acetylsalicylic Acid Combined With Pseudoephedrine in Common Cold
Status: COMPLETED
Conditions: Common Cold
Interventions: DRUG: Acetylsalicylic Acid (Aspirin, BAYE4465)|DRUG: Pseudoephedrine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Alpelisib in Pediatric and Adult Patients With Lymphatic Malformations Associated With a PIK3CA Mutation.
Status: RECRUITING
Conditions: Lymphatic Malformations
Interventions: DRUG: Alpelisib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tear Lipid Layer Thickness Changes With Use of Emollient and Non-Emollient Eye Drops
Status: COMPLETED
Conditions: Dry Eye Syndromes|Keratoconjunctivitis Sicca|Lacrimal Apparatus Diseases|Keratoconjunctivitis|Eye Diseases|Keratitis|Corneal Disease|Ophthalmic Solution
Interventions: OTHER: Systane Complete|OTHER: Systane Ultra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation to Compare the Safety and Efficacy of Cellular Matrix to Those of Ostenil® Plus and to Those of PRP Only
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Cellular Matrix / A-CP HA|DEVICE: Ostenil® Plus|DEVICE: RegenKit-BCT-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short- and Medium-term Evaluation of Mastoid Filling Using Bioactive Glass"
Status: RECRUITING
Conditions: Cholesteatoma
Interventions: DEVICE: verre bioactif 45S5 GlassBONE|DEVICE: verre bioactif S53P4 Bonalive
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Tolerability of Conversion From Oral, Injectable, or Infusion Disease Modifying Therapies to Dose-titrated Oral Siponimod (Mayzent) in Advancing RMS Patients
Status: COMPLETED
Conditions: Multiple Sclerosis|Relapsing Multiple Sclerosis|Advancing Multiple Sclerosis
Interventions: DRUG: Siponimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Overactive Bladder Treatment Access and Adherence
Status: NOT_YET_RECRUITING
Conditions: Overactive Bladder Syndrome|Urinary Incontinence
Interventions: BEHAVIORAL: Patient Engagement Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Red Blood Cell ATP Release and Vascular Function in Humans
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DRUG: Fasudil Hydrochloride|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: GRN1005 for Brain Metastases From Breast or Lung Cancer
Status: WITHDRAWN
Conditions: Breast Cancer|Lung Neoplasms|Breast Neoplasms|Lung Cancer
Interventions: DRUG: Trastuzumab|DRUG: GRN 1005
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Combined Suprascapular and Axillary Nerve Blocks for Arthroscopic Shoulder Surgery
Status: COMPLETED
Conditions: Arthroscopic Shoulder Surgery|Suprascapular Nerve Block|Axillary Nerve Block
Interventions: PROCEDURE: Suprascapular nerve- axillary nerve block combination|PROCEDURE: Subacromial infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Evaluation of Modified Yoga in Systemic Lupus Erythematosus (SLE)
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: OTHER: Standard care plus Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: IL3 CAR-T Cell Therapy for Patients With CD123 Positive Relapsed and/or Refractory Acute Myeloid Leukemia
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: IL3 CAR T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Safety Trial Assessing an Innovative Tumor Molecular and Cellular Print Medical Device in Glioma
Status: UNKNOWN
Conditions: Glioma : Oligodendroglioma or Astrocytoma
Interventions: DEVICE: Brain Tissue Imprint - Medical Device (ProTool)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study on Immunogenicity, Reactogenicity and Safety of the VACΔ6 Vaccine in Volunteers Aged 18-60 Years
Status: COMPLETED
Conditions: Smallpox|Monkeypox|Cowpox|Vaccinia Virus Infection
Interventions: BIOLOGICAL: VAC∆6 vaccine (10⁷ PFU)|BIOLOGICAL: VAC∆6 vaccine (10⁶ PFU)|BIOLOGICAL: Live Smallpox Vaccine|OTHER: Placebo (Sodium chloride bufus, 0.9%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Behavioral Interventions for Motivation, Psychological Distress and Quality of Life Among Individuals With Smoking Cessation: A Randomized Control Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Cognitive Behavior Intervention for Psychological Distress, Motivation and Quality of Life Among Individual With Smoking Cessation
Interventions: BEHAVIORAL: Behavioral Psychoeducational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sotevtamab (AB-16B5) Combined With FOLFOX as Neoadjuvant Treatment Prior to Resection of Colorectal Cancer Liver Metastasis
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: BIOLOGICAL: Sotevtamab|COMBINATION_PRODUCT: FOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 3T, a Sex-Positive HIV/STI Mobile App Intervention for Young Black Men Ages 14-19 Attracted to Men
Status: UNKNOWN
Conditions: HIV/AIDS and Infections|Sexual Behavior|Health Knowledge, Attitudes, Practice
Interventions: BEHAVIORAL: 3T Tune in! Turn on! Turn up!|BEHAVIORAL: General Health App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Lenzilumab and Axicabtagene Ciloleucel in Participants With Relapsed or Refractory Large B-Cell Lymphoma
Status: TERMINATED
Conditions: Relapsed/Refractory Large B-cell Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: Lenzilumab|BIOLOGICAL: Axicabtagene Ciloleucel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polatuzumab Vedotin and Zanubrutinib Plus R-CHP for Patients With Newly Diagnosed Untreated Non-GCB DLBCL
Status: ENROLLING_BY_INVITATION
Conditions: Effects of Chemotherapy|Safety Issues
Interventions: DRUG: Polatuzumab Vedotin|DRUG: Zanubrutinib|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MK0657 in Parkinson's Disease Patients (0657-006)
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: MK0657|DRUG: Comparator: Placebo (unspecified)|DRUG: Comparator: levodopa|DRUG: Comparator: carbidopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: In Vitro Assessment of a Breath-synchronized Vibrating Mesh Nebulizer During Non Invasive Ventilation
Status: COMPLETED
Conditions: Respiratory Diseases|Lung Diseases|Cystic Fibrosis|COPD|Asthma
Interventions: DRUG: Nebulization of Amikacin during NIV (RR: 15 cycles/minute)|DRUG: Nebulization of Amikacin during NIV (RR: 25 cycles/minute)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Software-guided Cognitive Stimulation to Prevents Delirium
Status: COMPLETED
Conditions: Delirium in Old Age
Interventions: OTHER: Prevention software|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison on Efficacy and Safety of Three Inpatient Insulin Therapy in Type2 DM
Status: COMPLETED
Conditions: Diabetes Mellitus (DM)
Interventions: DRUG: regular insulin|DRUG: 70/30 insulin|DRUG: Glargine|DRUG: glulisine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Valve Replacement Guided by Biomarkers of LV Decompensation in Asymptomatic Patients with Severe AS
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Valve Stenosis|Hypertrophy, Left Ventricular
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of LMT1-48 on Reducing Body Fat in Overweight Subject
Status: COMPLETED
Conditions: Overweight
Interventions: DIETARY_SUPPLEMENT: LMT1-48|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Weekly Tisotumab Vedotin for Patients With Platinum-Resistant Ovarian Cancer With Safety Run-in (innovaTV 208)
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: DRUG: tisotumab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Spironolactone on Acute Kidney Injury in Patients Undergoing Coronary Angiography
Status: COMPLETED
Conditions: Acute Kidney Injury|IHD|Contrast-induced Nephropathy
Interventions: DRUG: Spironolactone|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Different Anti-Asthmatic Treatments on Lung Function and on Exercise-Induced Bronchoconstriction in Children With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: budesonide and montelukast|DRUG: budesonide and formoterol|DRUG: montelukast|DRUG: budesonide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of Sunitinib Malate (SU011248) In Patients With Gastrointestinal Stromal Tumor (GIST)
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Sunitinib malate (SU011248)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eyes That Do Not Meet the Eligibility Criteria of Clinical Trials on Age-Related Macular Degeneration: Proportion of the Real-World Patient Population and Reasons for Exclusion
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: DRUG: Intravitreal anti-vascular endothelial growth factor injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HIP Mobile: A Community-based Monitoring, Rehabilitation and Learning e-System for Patients Following a Fracture
Status: COMPLETED
Conditions: Hip Fractures
Interventions: DEVICE: HIP Mobile e-Monitoring support|OTHER: Workbook support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Emotional Disorders During Treatment by Interferon Beta in Relapsing-remitting Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing, Remitting
Interventions: DRUG: Interferon beta-1a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes Mandible: Buffered 1% vs. Non-Buffered 1% Lidocaine
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Motor Learning in People With Cerebral Palsy by Using Virtual Reality.
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: BEHAVIORAL: Right hemiparesis, right upper limb.|BEHAVIORAL: Right hemiparesis, left upper limb|BEHAVIORAL: Left hemiparesis, left upper limb|BEHAVIORAL: Left hemiparesis, right upper limb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Benefits of Additional Complex Fractionated Atrial Electrogram Targeted Catheter Ablation for Longstanding Persistent Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: atrial electrogram and liner ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Subtalar Arthrodesis by Single Versus Double Screws
Status: NOT_YET_RECRUITING
Conditions: Subtalar Osteoarthritis Secondary to Inflammatory Arthritis
Interventions: PROCEDURE: Subtalar Arthrodesis by Screws
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Medical Treatment for Methamphetamine Addiction
Status: COMPLETED
Conditions: Methamphetamine|Amphetamine Dependence|Pharmacogenetics|Methamphetamine Dependence|Substance Abuse
Interventions: DRUG: Bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compliance With ERAS Protocol in Pancreatic Surgery, Stress Response and Outcomes
Status: RECRUITING
Conditions: ERAS|Pancreas Cancer|Pancreas; Fistula|Delayed Gastric Emptying|Surgery-Complications|Pancreatic Hemorrhage|PROMs
Interventions: PROCEDURE: ERAS protocol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Finnish Trial on Practices of Anterior Cervical Decompression (FACADE) Comparing Outpatient vs. Inpatient Care
Status: COMPLETED
Conditions: Cervical Radiculopathy
Interventions: PROCEDURE: Discharge on the day of surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Thickened Feeds to Treat Gastroesophageal Reflux in Children Admitted After Choking Spell
Status: TERMINATED
Conditions: Apparent Life Threatening Event|Gastroesophageal Reflux|Aspiration
Interventions: DIETARY_SUPPLEMENT: Rice cereal|DIETARY_SUPPLEMENT: Enfamil AR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telemedicine in Patients With Inflammatory Bowel Disease (TELE-IBD)
Status: COMPLETED
Conditions: Inflammatory Bowel Disease|Crohn's Disease|Ulcerative Colitis|Indeterminate Colitis
Interventions: BEHAVIORAL: Home Monitoring|BEHAVIORAL: Home Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dual Add-on Therapy in Type 2 Diabetes Poorly Controlled With Metformin Monotherapy
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type II
Interventions: DRUG: Retagliptin, Henagliflozein, metformin XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PENS or TENS for Pain in Liver Cancer
Status: COMPLETED
Conditions: Pain|Cancer Pain|Liver Neoplasms
Interventions: DEVICE: PENS|DEVICE: TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Kineret® (Anakinra) in Rheumatoid Arthritis (RA) Subjects Using aSelf-Reported Questionnaire
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DEVICE: SimpleJectTM|DRUG: Kineret® (Anakinra)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Su-Jok Application and Progressive Muscle Relaxation Exercises in Coping With Premenstrual Syndrome
Status: RECRUITING
Conditions: Premenstrual Syndrome
Interventions: PROCEDURE: Progressive Muscle Relaxation Exercise Group|PROCEDURE: Su-Jok Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: RCT on Ketorolac and Tramadol in Bone Fractures Pain of Child
Status: COMPLETED
Conditions: Fracture|Pain
Interventions: DRUG: ketorolac|DRUG: tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effects of Functional Inspiratory Muscle Training in Patients With Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DEVICE: Functional inspiratory muscle training group|DEVICE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of an Oral Immunomodulatory Nutrient on Survival During Postoperative Concomitant Chemoradiotherapy in Head and Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DIETARY_SUPPLEMENT: Immunomodulating oral supplementation|DIETARY_SUPPLEMENT: Sip feed control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Cohort Study to Compare the Hospitalization Between Naive Sacubitril/Valsartan and Naive ACEi/ARBs Heart Failure Patients With Reduced Ejection Fraction Using Secondary US Electronic Health Records Data
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Sacubitril/valsartan|DRUG: ACEi/ARB
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunogenicity and Safety of NBP608 Compared to Varivax in Healthy Children 12 Months to 12 Years of Age
Status: COMPLETED
Conditions: Varicella
Interventions: BIOLOGICAL: NBP608|BIOLOGICAL: Varivax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Functional Treatment of Patients With Backward Positioned Chins on the Jaw Joint and Movements
Status: COMPLETED
Conditions: Malocclusion, Angle Class II|Retrognathism|TMJ
Interventions: DEVICE: Activator|DEVICE: Twin Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interleukin-12 and Interferon Alfa in Treating Patients With Metastatic Malignant Melanoma
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage IV Melanoma
Interventions: BIOLOGICAL: recombinant interleukin-12|BIOLOGICAL: recombinant interferon alfa|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post SBRT Pulmonary Metastasectomy (PSPM) Trial
Status: UNKNOWN
Conditions: Surgical Resection|Stereotactic Body Radiotherapy|Lung Cancer|Pulmonary Metastasectomy
Interventions: PROCEDURE: Surgical resection and stereotactic body radiation therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sitagliptin Plus Granulocyte-colony Stimulating Factor in Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Lenograstim (GRANOCYTE)=GCSF|DRUG: Sitagliptin (Januvia)|DRUG: Sodium Chloride (NaCl) 0.9 %|DRUG: Gelatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Rinsulin R (GEROPHARM) and Humulin Regular (Eli Lilly) Euglycemic Hyperinsulinemic Clamp Method
Status: COMPLETED
Conditions: Bioequivalence|Therapeutic Equivalency
Interventions: DRUG: Humulin® Regular|DRUG: Rinsulin® R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transmucular Quadratus Lumborum Block: Potential Quadriceps Muscle Weakness
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: DRUG: Ropivacaine|OTHER: Quadriceps muscle strength|OTHER: Timed Up and Go|OTHER: Single-leg 6 meter timed hop test|OTHER: Temperature discrimination|OTHER: Pinprick test|DIAGNOSTIC_TEST: Blood samples|DIAGNOSTIC_TEST: Non-invasive blood pressure measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pulmonary Perfusion Heterogeneity and Compliance in Patients With Pulmonary Hypertension Using Positron Emission Tomography Imaging
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: OTHER: CT imaging, functional PET imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Hypnosis and Direct Autonomic Experience Influence on Chronic Symptoms
Status: UNKNOWN
Conditions: Restless Legs Syndrome|Multiple Sclerosis|Trauma, Psychological|Chronic Disease|Trauma
Interventions: BEHAVIORAL: Self-Hypnosis|BEHAVIORAL: Direct Autonomic Experience Control
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Placebo-controlled Evaluation of Ropivacaine Efficacy by Local Infiltrations
Status: COMPLETED
Conditions: Hepatectomy|Pain|Metastasis
Interventions: DRUG: Ropivacaine|DRUG: Physiological serum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: The Effect of Exercise on Blood Parameters Related to Dialysis Patients' Survival
Status: COMPLETED
Conditions: Chronic Kidney Diseases|End Stage Renal Disease|Hemodialysis
Interventions: OTHER: Intradialytic exercise group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Correlation of a D-dimer Testing Protocol With Venous Thromboembolism in Surgical Colorectal Patients
Status: WITHDRAWN
Conditions: Venous Thromboses|Colorectal Cancer|Diverticular Diseases|Crohn Disease|Ulcerative Colitis|Deep Vein Thrombosis
Interventions: DIAGNOSTIC_TEST: D-dimer and lower limb venous duplex
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Immediate Smoking Cessation Interventions for Smokers With Chronic Airway Diseases
Status: COMPLETED
Conditions: Tobacco Cessation|Asthma COPD|Bronchiectasis Adult
Interventions: OTHER: Immediate smoking cessation support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Immune Program of Recombinant Novel Coronavirus（COVID-19) Vaccine (CHO Cell)
Status: UNKNOWN
Conditions: Coronavirus Disease 2019
Interventions: BIOLOGICAL: Recombinant novel coronavirus vaccine (CHO cell)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Evaluation of the DIMI RRT System In-Center to Demonstrate Safety and Usability in the Home Environment
Status: WITHDRAWN
Conditions: ESRD|Hemodialysis
Interventions: DEVICE: The DIMI Renal Replacement Therapy (RRT) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INSPIRE Trial for Abdominal Infections
Status: ACTIVE_NOT_RECRUITING
Conditions: Abdominal (ABD) Infection
Interventions: OTHER: Arm 1: Routine Care|OTHER: Arm 2: INSPIRE Stewardship Bundle for Abdominal Infection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER