pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Trauma Follow-Up Prediction (Project 2: Aim 2)
Status: NOT_YET_RECRUITING
Conditions: Injury Traumatic|Injuries
Interventions: DEVICE: Optimized version of the mHealth screening tool (intervention) using the machine learning approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparing Efficacy and Safety of Insulin Degludec/Insulin Aspart Twice Daily and Biphasic Insulin Aspart Twice Daily in Subjects With Type 2 Diabetes Mellitus Before, During and After Ramadan
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/insulin aspart|DRUG: biphasic insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Esomeprazole in Healthy Adult Subjects Under Fasting Condition
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Test product (T) 40 mg Hard Gelatin Capsules|DRUG: Reference product (R) 40 mg Hard Gelatin Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Antisecretory Effect of a Single Dose of Rabeprazole 20 mg and Omeprazole 20 mg in Obese Subjects
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: Omeprazole|DRUG: Rabeprazole|DRUG: Lactose
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Combined PEX, Rituximab and Steroids in Acute Idiopathic Pulmonary Fibrosis Exacerbations
Status: COMPLETED
Conditions: IPF
Interventions: DRUG: Combined Plasma Exchange (PEX), Rituximab, and Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: iNav-based, Automated Coronary Magnetic Resonance Angiography for the Detection of Coronary Artery Stenosis
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Stenosis
Interventions: DIAGNOSTIC_TEST: Coronary Magnetic Resonance Angiography (CMRA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Tocilizumab in Modifying the Inflammatory Parameters of Patients With COVID-19 (COVITOZ-01)
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: Tocilizumab 20 MG/ML Intravenous Solution [ACTEMRA]_#1|DRUG: Tocilizumab 20 MG/ML Intravenous Solution [ACTEMRA]_#1 (2 doses)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Finerenone on Vascular Stiffness and Cardiorenal Biomarkers in T2D and CKD (FIVE-STAR)
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes|Chronic Kidney Diseases
Interventions: DRUG: Finerenone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of the Acute Myeloblastic Leukaemia in Patients Over 65 Years
Status: COMPLETED
Conditions: Acute Myeloblastic Leukaemia
Interventions: DRUG: ARA-C|DRUG: Idarubicin|DRUG: Leucomax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicentre Study To Assess Changes In Bone Mineral Density Of The Switch From Tenofovir To Abacavir In Hiv-1-Infected Subjects With Loss Of Bone Mineral Density
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Switch from tenofovir to abacavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Silybin - Vitamin E- Phospholipids Complex Reduces Liver Fibrosis in Patients With Chronic Hepatitis C Treated With Peg-IFN-a and RBV
Status: COMPLETED
Conditions: Liver Fibrosis
Interventions: DRUG: Silybin 94 mg + vitamin E 90 mg + phospholipids 194 mg complex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Kinesiotaping on Ankle Stability
Status: COMPLETED
Conditions: Sprain and Strain of Ankle
Interventions: DEVICE: Leukotape K|DEVICE: Sham kinesiotape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults
Status: RECRUITING
Conditions: Seizures|Lennox Gastaut Syndrome
Interventions: DRUG: Carisbamate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life and Pain Pressure Threshold in Response to Scar Release Techniques for Chronic Transverse Abdominal Scar
Status: NOT_YET_RECRUITING
Conditions: Cesarean Section Complications
Interventions: OTHER: myofascial induction and direct scar release techniques|DEVICE: therapeutic ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Medico-economical Evaluation of Patient-hotel in Urology
Status: COMPLETED
Conditions: Surgery for Sacral Nerve Neurostimulation|Surgery for Urinary Artificial Sphincter|Surgery for Prosthetic Penile Implant
Interventions: OTHER: postoperative hotel|OTHER: conventional hospitalization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Prospective Study of Pembrolizumab Combining Chemotherapy in Advanced NSCLC Patients With EGFR Exon 21 Point Mutation.
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer|Immune Checkpoint Inhibitor|EGFR Exon 21 Mutation
Interventions: DRUG: Pembrolizumab, pemetrexed, platinum|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-based Intervention to Prevent Risky Driving
Status: COMPLETED
Conditions: Adolescent|Accidents, Traffic|Attention|Motor Vehicles
Interventions: BEHAVIORAL: Risky driving prevention|BEHAVIORAL: Control group general health promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sham Controlled Study of Renal Denervation for Untreated Stage I and II Hypertension
Status: UNKNOWN
Conditions: Hypertension
Interventions: DEVICE: Ultrasound|DEVICE: Sham Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DISTRESS Trial Functional Disorders - the DISTRESS Trial
Status: RECRUITING
Conditions: Bodily Distress Syndrome|Functional Somatic Disorder
Interventions: OTHER: Diagnostic evaluation at the Diagnostic Clinic for Functional Disorders|OTHER: Diagnostic as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of ELKa, the Toolset for Food Exchanges Calculation on Metabolic Control in Pediatric Diabetic Patients.
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: ELKa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lymph Node Mapping and Sentinel Lymph Node Identification in Patients With Stage IB1 Cervical Cancer
Status: TERMINATED
Conditions: Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Cervical Squamous Cell Carcinoma|Stage I Cervical Cancer
Interventions: DRUG: Isosulfan Blue|PROCEDURE: Lymph Node Mapping|PROCEDURE: Lymphangiography|DRUG: Methylene Blue|PROCEDURE: Radionuclide Imaging|PROCEDURE: Sentinel Lymph Node Biopsy|RADIATION: Technetium Tc-99m Sulfur Colloid|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Balovaptan in Adults With Autism Spectrum Disorder With a 2-Year Open-Label Extension
Status: TERMINATED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: Balovaptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Curcumin-Simvastatin-EDTA in the Treatment of Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: PROCEDURE: currettage|DRUG: curcumin simvastatin paste|DRUG: EDTA root conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Long-lasting Infusion of Vasoactive Intestinal Peptide (VIP) on Headache, Cranial Hemodynamic and Autonomic Symptoms in Healthy Volunteers
Status: COMPLETED
Conditions: Headache Disorders
Interventions: DRUG: Vasoactive Intestinal Peptide (VIP) and Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Excessive Sweating Caused by Antidepressants: Measurement and Treatment With Glycopyrrolate (AIDES-G)
Status: TERMINATED
Conditions: Hyperhydrosis|Depression
Interventions: DRUG: Glycopyrrolate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deficit in Quadriceps Voluntary Activation After Anterior Cruciate Ligament Reconstruction: Roles of the "Learned Non-use" Paradigm and the Interhemispheric Inhibition
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Injuries
Interventions: DIAGNOSTIC_TEST: Pathologic group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Eliglustat in Chinese Pediatric Patients With Gaucher Disease Type 1 and Type 3
Status: NOT_YET_RECRUITING
Conditions: Gaucher Disease
Interventions: DRUG: Eliglustat Tartrate Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Online Self-management Intervention for Type 2 Diabetes Mellitus
Status: WITHDRAWN
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: covivio (additional to treatment as usual)|OTHER: treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of HMI-115 in Subjects With Endometriosis-Associated Pain
Status: RECRUITING
Conditions: Endometriosis
Interventions: DRUG: HMI-115|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Matrix Rhythm Therapy on Increased Muscle Tone, Balance and Gait Parameters in Stroke Survivors
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Bobath therapy and Matrix Rhythm Therapy|OTHER: Bobath therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive MRI to Quantify the Effect of Secretin on Pancreatic Blood Flow and Perfusion in Healthy Volunteers
Status: COMPLETED
Conditions: Chronic Pancreatitis
Interventions: DRUG: Secretin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of High-dose n-3 Fatty Acids on Clinical Outcome and Serum Lipids - Omacor Following Acute Myocardial Infarction
Status: COMPLETED
Conditions: Coronary Disease|Myocardial Infarction
Interventions: DRUG: EPA / DHA / Alpha-Tocopherol|DRUG: Corn Oil / Alpha-Tocopherol (4 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Evaluation of TheraSphere to Treat Inoperable Liver Cancer With Blockage of the Portal Vein
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: TheraSphere®|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis
Status: RECRUITING
Conditions: Parkinson's Disease Psychosis
Interventions: DRUG: Pimavanserin|DRUG: Quetiapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Heme Oxygenase (HO) Activity and Adenosine Induced Vasodilation
Status: TERMINATED
Conditions: Atherosclerotic Cardiovascular Disease
Interventions: DRUG: L-arginine + heme arginate|DRUG: Heme arginate + L-arginine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of Two Study Drinks in Detoxification of Environmental Toxicants and Carcinogens
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Freeze dried Powder|DIETARY_SUPPLEMENT: Placebo Preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalency Study of Amlodipine Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Hypertension|Chronic Stable Angina|Vasospastic Angina
Interventions: DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of ICP-022 in Healthy Subjects
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus|Rheumatoid Arthritis
Interventions: DRUG: ICP-022|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Classification Based 'Cognitive Functional Therapy' in Patients With Non Specific Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: OTHER: Cognitive Functional Therapy|OTHER: Manual therapy and exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laser Acupuncture and Pain Management in Preterm Infants Undergoing Patent Ductus Arteriosus Ligation
Status: COMPLETED
Conditions: Preterm Newborns
Interventions: DEVICE: Laser stimulation|DEVICE: Fake laser stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Controlled Trial of Ganaxolone in Adult Uncontrolled Partial-Onset Seizures
Status: COMPLETED
Conditions: Partial Epilepsy|Catamenial Epilepsy
Interventions: DRUG: Ganaxolone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of XL844 Administered as a Single Agent and in Combination With Gemcitabine in Adults With Advanced Malignancies
Status: TERMINATED
Conditions: Cancer|Lymphoma
Interventions: DRUG: XL844|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine If a New Shigella Vaccine is Safe, Induces Immunity and The Best Dose Among Kenyan Infants
Status: COMPLETED
Conditions: Shigellosis
Interventions: BIOLOGICAL: Shigella 4V|BIOLOGICAL: MenACWY|BIOLOGICAL: Rabies|BIOLOGICAL: Diphtheria, Tetanus and Pertussis (DTaP)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Randomised Double Blind Placebo Controlled Cross Over Design of the Efficacy of Topical Morphine for Inflammatory Pain in Children With Epidermolysis Bullosa
Status: COMPLETED
Conditions: Epidermylosis Bullosa
Interventions: DRUG: topical opiod|DRUG: morphine sulphate in intrasite gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Inadequacy in Rural Populations, Evaluation of Correction by Food Supplementation
Status: COMPLETED
Conditions: Vitamin D Insufficiency|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol (vitamin D3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Camostat and Artemisia Annua vs Placebo in COVID-19 Outpatients
Status: TERMINATED
Conditions: Covid19|Diabetes|Hypertension|Obesity
Interventions: DRUG: Camostat Mesilate|DRUG: Artemisia Annua Leaf
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Cabozantinib in Combination With Atezolizumab Versus Second NHT in Subjects With mCRPC
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Prostate Cancer|Prostate Adenocarcinoma
Interventions: DRUG: Cabozantinib|DRUG: Atezolizumab|DRUG: Abiraterone Acetate|DRUG: Enzalutamide|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-based Nurse Intervention in the Care of High Risk of Death Patients After Discharge From Geriatric Department
Status: NOT_YET_RECRUITING
Conditions: Health Services for the Aged|Advance Care Planning
Interventions: OTHER: Advance care plan|OTHER: Ergonomic analysis|OTHER: Evaluation of intervention acceptability
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Eosinophilic Cationic Protein as a Biomarker in Diagnosis of Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DIAGNOSTIC_TEST: Eosinophilic Cationic Protein biomarker
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Polyphenols of Pomegranate Fruit Peel Extract on Inflammation and Oxidative Stress in Metabolic Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Polyphenols of pomegranate fruit peel extract (PoPex)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Acceptability of ReCognitionVR-based Cognitive Stimulation in Surgical Patients
Status: ENROLLING_BY_INVITATION
Conditions: Surgery|Delirium|Delirium, Post-Operative
Interventions: OTHER: Virtual Reality Software|OTHER: Traditional Orientation Methods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Clinical Study of CD19/BCMA CAR-T Cells in the Treatment of Refractory POEMS Syndrome, Amyloidosis, Autoimmune Hemolytic Anemia, and Vasculitis
Status: RECRUITING
Conditions: POEMS Syndrome|Amyloidosis|Autoimmune Hemolytic Anemia|Vasculitis
Interventions: BIOLOGICAL: CD19/BCMA CAR T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of an Alpha-glucosidase Inhibitor to Block Cardiac Events in Patients With MI and IGT
Status: TERMINATED
Conditions: Impaired Glucose Tolerance|Myocardial Infarction
Interventions: DRUG: voglibose|BEHAVIORAL: diet and exercise therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial Comparing the Effect of Exercise on Blood Glucose in Subjects With Type 1 Diabetes, Who Are Treated With Either Insulin Degludec or Insulin Glargine
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Confirmatory Trial in the Evaluation of Ca Electroporation for the Treatment of Cutaneous Metastases
Status: COMPLETED
Conditions: Cutaneous Melanoma
Interventions: PROCEDURE: Calcium Electroporation|PROCEDURE: Bleomycin based electrochemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Psychostimulants Effects on Brain Functional Connectivity in Youth With Attention Deficit Hyperactivity Disorder
Status: UNKNOWN
Conditions: Adhd
Interventions: DRUG: Methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Efficacy and Safety of Bisacodyl and Lactulose as a Preparation for Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy Preparation
Interventions: DRUG: 90 grams of Crystalline Lactulose|DRUG: 135 grams of Crystalline Lactulose|DRUG: 180 grams of Crystalline Lactulose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Novel Glucagon Receptor Antagonist REMD-477 on Glucose and Adipocyte Metabolism in T2DM
Status: COMPLETED
Conditions: Type 2 Diabetes|Glucose Tolerance Impaired|Insulin Sensitivity
Interventions: DRUG: REMD-477|DRUG: Placebo Subcutaneous injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Homonymous Hemianopia in Childhood
Status: ENROLLING_BY_INVITATION
Conditions: Homonymous Hemianopia
Interventions: OTHER: Prism|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Bioequivalence Study of 2.5-mg Saxagliptin and 500-mg Glucophage in Tablets and a Fixed-dose Combination Tablet in Healthy Participants
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Saxagliptin, 2.5 mg + Metformin, 500 mg (fasted state)|DRUG: Saxagliptin, 2.5 mg /Metformin, 500 mg FDC (fasted state)|DRUG: Saxagliptin, 2.5 mg + Metformin, 500 mg (fed state)|DRUG: Saxagliptin, 2.5 mg /Metformin, 500 mg FDC (fed state)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: To Evaluate the Efficacy and Safety in Subjects With Functional Dyspepsia
Status: COMPLETED
Conditions: Functional Dyspepsia
Interventions: DRUG: Z-338
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving the Recovery and Outcome Every Day After the ICU
Status: COMPLETED
Conditions: Delirium|Alzheimer Disease
Interventions: BEHAVIORAL: Physical Exercise Intervention|BEHAVIORAL: Cognitive Training Intervention|BEHAVIORAL: Stretching Control|BEHAVIORAL: Cognitive Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment for Classical Hodgkin Lymphoma in Children and Adolescents
Status: RECRUITING
Conditions: Classical Hodgkins Lymphoma in Children and Adolescents.
Interventions: RADIATION: Radiotherapy:|DRUG: Vincristine|DRUG: Etoposide|DRUG: Prednisone|DRUG: Doxorubicin|DRUG: Dacarbazine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Letrozole And Clomiphene Citrate For Induction of Ovulation In Polycystic Ovarian Syndrome(PCOS)
Status: COMPLETED
Conditions: Polycystic Ovarian Syndrome
Interventions: DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Childhood Acute Basophilic Leukemia|Childhood Acute Eosinophilic Leukemia|Childhood Acute Erythroleukemia (M6)|Childhood Acute Megakaryocytic Leukemia (M7)|Childhood Acute Minimally Differentiated Myeloid Leukemia (M0)|Childhood Acute Monoblastic Leukemia (M5a)|Childhood Acute Monocytic Leukemia (M5b)|Childhood Acute Myeloblastic Leukemia With Maturation (M2)|Childhood Acute Myeloblastic Leukemia Without Maturation (M1)|Childhood Acute Myelomonocytic Leukemia (M4)|Childhood Myelodysplastic Syndromes|de Novo Myelodysplastic Syndromes|Secondary Acute Myeloid Leukemia|Secondary Myelodysplastic Syndromes|Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies
Interventions: DRUG: asparaginase|DRUG: daunorubicin hydrochloride|DRUG: cytarabine|DRUG: thioguanine|DRUG: etoposide|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Phenylephrine on Nasal Congestion in Participants With Seasonal Allergic Rhinitis (P08156 AM2)(Completed)
Status: COMPLETED
Conditions: Rhinitis|Seasonal Rhinitis
Interventions: DRUG: Phenylephrine HCl|DRUG: Placebo|DRUG: Loratadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Low-level Laser Therapy, Intracanal Cryotherapy and Their Combination, on Post-endodontic Pain Level
Status: UNKNOWN
Conditions: Low-level Light Therapy|Cryotherapy
Interventions: DEVICE: Low Level Laser therapy|PROCEDURE: Intra canal Cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fludarabine and Cytarabine in Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Leukemia|AML|MDS|CML
Interventions: DRUG: Cytarabine|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Life Evaluation After Cataract Surgery Using 4 Types of Intraocular Lens Implant Combinations
Status: RECRUITING
Conditions: Cataract|Intraocular Lens Implant
Interventions: DEVICE: Zeiss CT Asphina / Zeiss CT Asphina|DEVICE: Zeiss AT Lara/ Zeiss AT Lisa Tri|DEVICE: Zeiss CT Asphina/ Zeiss AT Lara|DEVICE: Zeiss AT Lara / Zeiss AT Lara
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Pilates Mat Versus Cervical Stabilization Exercises on Balance in Young Adults With Forward Head Posture
Status: COMPLETED
Conditions: Musculoskeletal Diseases
Interventions: OTHER: Pilates mat exercises|OTHER: cervical stabilization exercises|OTHER: conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Randomized Controlled Trial to Compare the Clinical Outcomes With Six Months of Therapy With Oral Itraconazole Versus Oral Voriconazole for Management of Treatment naïve Subjects With Chronic Pulmonary Aspergillosis
Status: COMPLETED
Conditions: Chronic Pulmonary Aspergillosis
Interventions: DRUG: Itraconazole 200 mg|DRUG: Voriconazole 200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a a Biofunctional Textile in the Management of Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: OTHER: chitosan coated textile|OTHER: chitosan free cotton long sleeved t-shirts and pants.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Sedation and Analgesia in Colonoscopy Treatment of Colorectal Polyps
Status: RECRUITING
Conditions: Colonoscopy|Sedation and Analgesia
Interventions: DRUG: midazolam and dezocine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tirelizumab Plus Surgery vs Surgery Alone for Recurrent Nasopharyngeal Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Tirelizumab|PROCEDURE: salvage surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Etodolac and Propranolol in Patients With Clinically Progressive Prostate Cancer
Status: TERMINATED
Conditions: Prostatic Neoplasms
Interventions: DRUG: VT-122|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Generic Fluorouracil 0.5% Cream and 0.5% Carac® and Placebo
Status: COMPLETED
Conditions: Actinic Keratoses
Interventions: DRUG: Brand Carac|DRUG: Generic 0.5% 5-fluorouracil cream|OTHER: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Sugar-Sweetened Beverage Reduction Intervention for Native American Men
Status: RECRUITING
Conditions: Cardiovascular Disorder|Coronary Artery Disease|Diabetes Mellitus|Obesity-Related Malignant Neoplasm
Interventions: OTHER: Education Intervention|OTHER: Interview|PROCEDURE: Discussion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Granulocyte-Macrophage Stimulating Factor in the Treatment of Peripheral Arterial Disease
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DRUG: Granulocyte-Macrophage Stimulating Factor (GM-CSF)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sleepiness and the Effects of CPAP on Salivary Cortisol and Alpha-Amylase Levels in Patients With Sleep Apnea
Status: COMPLETED
Conditions: Sleep Apnea|Sleep Disordered Breathing
Interventions: DEVICE: 14 days of placebo therapy|DEVICE: 14 days of CPAP therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azithromycin and Coronary Events Study (ACES)
Status: COMPLETED
Conditions: Coronary Disease|Heart Diseases|Myocardial Infarction|Cardiovascular Diseases
Interventions: DRUG: azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Improvement in Bronchial Asthma in Patients With Extraesophageal Reflux After Acid Suppression
Status: COMPLETED
Conditions: Bronchial Asthma|Gastroesophageal Reflux
Interventions: DRUG: Rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Sequestrant Colesevelam in Bile Acid Diarrhoea
Status: COMPLETED
Conditions: Bile Acid Malabsorption|Chronic Diarrhea
Interventions: DRUG: Colesevelam Hydrochloride|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effects of Cocoa Flavanol on Cognition Assessed Online
Status: COMPLETED
Conditions: Aging|Cognitive Change
Interventions: DIETARY_SUPPLEMENT: Cocoa Extract|DIETARY_SUPPLEMENT: Cocoa Extract Placebo|DIETARY_SUPPLEMENT: Multivitamin|DIETARY_SUPPLEMENT: Multivitamin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cranial Electrotherapy Stimulation: Piloting a Road to PTSD Prevention in First Responders
Status: ENROLLING_BY_INVITATION
Conditions: Adults
Interventions: DEVICE: Alpha-Stim AID cranial electrotherapy stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety/Efficacy of Systane Free vs Refresh Liquigel
Status: COMPLETED
Conditions: Dry Eye
Interventions: OTHER: Systane Free Lubricant Eye Drops|OTHER: Refresh Liquigel Lubricant Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Sexual Dysfunction in Hypogonadal Men With Epilepsy With Testosterone and Either Anastrozole or Placebo
Status: COMPLETED
Conditions: Seizure Disorder|Hypogonadism|Erectile Dysfunction
Interventions: DRUG: Anastrozole 1mg|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Ledipasvir/Sofosbuvir (LDV/SOF) Fixed Dose Combination (FDC) for 12 or 24 Weeks in Kidney Transplant Recipients With Chronic HCV Infection
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: LDV/SOF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Standardized vs Individualized Seat Height on 1-minute Sit-to-stand Performance
Status: COMPLETED
Conditions: Healthy Individuals
Interventions: DIAGNOSTIC_TEST: Standardized 1-minute sit-to-stand test|DIAGNOSTIC_TEST: Individualized 1-minute sit-to-stand test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Benefit of Adding Durvalumab After Chemotherapy, Durvalumab and Surgery in Patients With Early-stage, Operable, Non-small Cell Lung Cancer.
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Adjuvant durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyoscine Butylbromide Effect on Duration of Labor
Status: COMPLETED
Conditions: Labor
Interventions: DRUG: Hyoscine Butylbromide 20Mg/1mL Injection|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of His Bundle Pacing in Treatment of Slow Arrhythmia on Function of Left Atrial and Ventricle in Short Term
Status: COMPLETED
Conditions: Slow Arrhythmia|His Bundle Pacing|Function of Left Atrial and Ventricle
Interventions: DEVICE: Dual Chamber Pacemaker|DEVICE: His Bundle Pacemaker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study for Comparison of the Effects Between Gasless Laparoscopy and Conventional Laparoscopy for Distal Gastric Cancer
Status: UNKNOWN
Conditions: Gastrectomy|Laparoscopy
Interventions: DEVICE: Conventional Laparoscopy|DEVICE: Gasless Laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Twice Weekly Hemodialysis in Patients With Residual Kidney Function
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemodialysis|Kidney Failure, Chronic
Interventions: OTHER: Twice weekly hemodialysis|OTHER: Thrice weekly hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: TMS-fNIRS Personalized Dosing
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder|Traumatic Brain Injury
Interventions: DEVICE: TMS-fNIRS over the dl-PFC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: DIAFAX I+II-Effects of Inhalative Anesthetics on Left Ventricular Diastolic Function
Status: TERMINATED
Conditions: Young Healthy Adults|Ventricular Dysfunction
Interventions: DRUG: TTE measurements under anesthesia with sevoflurane, isoflurane, desflurane, and remifentanyl|DRUG: Sevoflurane, Isoflurane, Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessing of Tooth Sensitivity Using Ibuprofen Before in Office-tooth Bleaching
Status: COMPLETED
Conditions: Inflammation|Pulpitis
Interventions: DRUG: Ibuprofen.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Somatostatin Receptors Imaging in Relapsing and Refractory Multiple Myeloma Patients
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DIAGNOSTIC_TEST: Gallium-68 labelled DOTA-conjugated SSTR targeting peptide PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Regorafenib Combined With PD-1 Inhibitor Therapy for Second-line Treatment of Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Regorafenib|PD-1 Inhibitor
Interventions: DRUG: Regorafenib|DRUG: PD-1 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stapled vs Hand Sewn Anastomosis in Roux en Y Gastric Bypass for Morbid Obesity: Randomized Clinical Trial
Status: UNKNOWN
Conditions: Morbid Obesity
Interventions: PROCEDURE: Roux en Y Gastric Bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obesity/Overweight in Persons With Early and Chronic Spinal Cord Injury (SCI)
Status: COMPLETED
Conditions: Overweight|Obese|Spinal Cord Injury
Interventions: BEHAVIORAL: Lifestyle Intervention|BEHAVIORAL: Exercise Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Psoriatic Arthritis Treated With Liraglutide Therapy: a QUality of Life and Efficacy Study
Status: WITHDRAWN
Conditions: Psoriatic Arthritis|Psoriasis|Impaired Glucose Tolerance|Type 2 Diabetes
Interventions: DRUG: liraglutide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nebulized Sub-dissociative Dose Ketamine at Three Different Dosing Regimens for Treating Acute Pain in the Pediatric ED
Status: RECRUITING
Conditions: Pain
Interventions: DRUG: Nebulized Sub-dissociative Dose Ketamine at either 0.75 mg/kg|DRUG: Nebulized Sub-dissociative Dose Ketamine at 1 mg/kg|DRUG: Nebulized Sub-dissociative Dose Ketamine at 1.5 mg/kg.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Bioavailability Study of Two Test Products of Fixed Dose Combination Capsule of Acetylsalicylic Acid (ASA) and Pantoprazole (Each Capsule Contains ASA 100 mg and Pantoprazole 20 mg) Under Fed Conditions
Status: COMPLETED
Conditions: Ulcers, Duodenal and Gastric
Interventions: DRUG: Test 1= ASA 100 mg and pantoprazole 20 mg capsule formulation one|DRUG: Test 2= ASA 100 mg and pantoprazole 20 mg capsule formulation two|DRUG: ASA 100 mg tablet|DRUG: Pantoprazole 20 mg gastro-resistant tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Neut During Potassium Chloride Replacement on Pain and Incidence of Phlebitis
Status: TERMINATED
Conditions: Hypokalemia
Interventions: DRUG: potassium chloride replacement|DRUG: Experimental - 4% Sodium Bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety Study of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% and Brimonidine 0.2%
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Brinzolamide 1%/brimonidine tartrate 0.2% ophthalmic suspension|DRUG: Brinzolamide ophthalmic suspension, 1%|DRUG: Brimonidine tartrate ophthalmic solution, 0.2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Whether Pharmacokinetic and Pharmacodynamic Interactions Exist Between Metformin and Canagliflozin (JNJ-28431754) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Metformin|DRUG: Canagliflozin (JNJ-28431754)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blockade of the Renin-angiotensin-aldosterone System in Patients With ARVD
Status: NOT_YET_RECRUITING
Conditions: Arrhythmogenic Right Ventricular Dysplasia
Interventions: DRUG: Spironolactone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Minocycline on Patients With Ischemic Stroke Undergoing Intravenous Thrombectomy
Status: RECRUITING
Conditions: Ischemic Stroke, Acute
Interventions: DRUG: Minocycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fascial Distortion Model in Tension Type Headache
Status: RECRUITING
Conditions: Postural; Defect|Tension-Type Headache|Pain, Neck|Craniovertebral; Syndrome|Proprioceptive Disorders
Interventions: OTHER: Fascial Distortion Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Marijuana Use, Strength Training, and Alcohol Consumption (MUSTAC) Study
Status: COMPLETED
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Eccentric Biceps Flexion|BEHAVIORAL: Concentric Biceps Flexion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Paclitaxel-Eluting Percutaneous Coronary Angioplasty (PTCA)-Balloon Catheter for the Treatment of Coronary Bifurcations
Status: COMPLETED
Conditions: Angioplasty
Interventions: PROCEDURE: Percutaneous coronary intervention (PCI)|PROCEDURE: PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ferumoxytol MRI in Assessing Response to Pembrolizumab in Patients With Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: Ferumoxytol|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Vaccination Using a 2nd Generation (E1/E2B/E3-Deleted) Adenoviral-COVID-19 in Normal Healthy Volunteers
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: hAd5-S-Fusion+N-ETSD vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-Habilitation Exercise Intervention
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Colon Cancer|Rectal Cancer|Diverticular Disease
Interventions: BEHAVIORAL: Exercise for Cancer Patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: "My Decision" Tubal Sterilization Decision Support Tool
Status: COMPLETED
Conditions: Tubal Sterilization|Women's Health|Contraception|Contraception Behavior|Reproductive Behavior
Interventions: BEHAVIORAL: "My Decision" tubal sterilization decision aid|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Single Doses of RO4998452 in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Placebo|DRUG: RO4998452
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION