pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Screening Trial of Nivolumab With Image Guided, Stereotactic Body Radiotherapy (SBRT) Versus Nivolumab Alone in Patients With Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC)
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma (HNSCC)
Interventions: DRUG: Nivolumab|RADIATION: Stereotactic Body Radiation Therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Empowerment Program on Children's Knowledge, Attitude, Self-Efficacy, and Practice of Nail Biting.
Status: COMPLETED
Conditions: Nail Biting
Interventions: BEHAVIORAL: Empowerment Program Based on BASNEF Model|BEHAVIORAL: Routine Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tipifarnib, Cytarabine, and Daunorubicin in Treating Older Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: tipifarnib
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimising Anterior Pallidal Deep Brain Stimulation for Tourette's Syndrome
Status: WITHDRAWN
Conditions: Tourette's Syndrome
Interventions: DEVICE: Deep brain stimulator ventral electrode up to 2 mA|DEVICE: Deep brain stimulator ventral electrode up to 3 mA|DEVICE: Deep brain stimulator dorsal electrode up to 2 mA|DEVICE: Deep brain stimulator dorsal electrode up to 3 mA|DEVICE: Deep brain stimulator empirical programming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindful Self-Regulation fMRI Pilot Study
Status: COMPLETED
Conditions: Psychiatric Problem|Depression|Anxiety|Neuroimaging|Self-Control
Interventions: BEHAVIORAL: Mindfulness Training for Primary Care (MTPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Evaluate the Long-term Safety and Efficacy of HSK16149 in Chinese Patients With Peripheral Neuralgia
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Neuropathic Pain
Interventions: DRUG: HSK16149 40mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Performance of CardiacSense PPG Sensor
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Study Procedure for Participants That Were Not in the Driving Group|DEVICE: Study Procedure for Participants That Were Included in the Driving Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zimura Compared to Sham in Patients With Autosomal Recessive Stargardt Disease (STGD1)
Status: ACTIVE_NOT_RECRUITING
Conditions: Stargardt's Macular Dystrophy
Interventions: DRUG: avacincaptad pegol|DRUG: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolically Fit CD19 CAR T-cell Therapy With CD34 Selection in Patients With CD19+ Relapsed/Refractory NHL, CLL/SLL
Status: RECRUITING
Conditions: B-cell Non Hodgkin Lymphoma|Chronic Lymphocytic Leukemia
Interventions: DRUG: Cyclophosphamide injection|DRUG: Fludarabine Injection|BIOLOGICAL: CD19-CD34t metabolically programmed CAR transduced T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects and Mechanism of Two Hybrid Exercise-cognitive Trainings in Mild Ischemic Stroke With Cognitive Decline
Status: COMPLETED
Conditions: Stroke Patients With Cognitive Decline
Interventions: BEHAVIORAL: Sequential training|BEHAVIORAL: Dual training|BEHAVIORAL: Control training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Adjuvant Supplements Prior to in IVF
Status: COMPLETED
Conditions: Dietary Supplements
Interventions: DIETARY_SUPPLEMENT: DHEA|DIETARY_SUPPLEMENT: DHEA+CoQ10+Tocotrienol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Balance and Resisted Training in Diabetic Peripheral Neuropathy.
Status: RECRUITING
Conditions: Diabetic Peripheral Neuropathy
Interventions: OTHER: Balance exercises|OTHER: Resisted exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Obstetrical Gel and Its Impact in Shortening the Duration of Labor in Women Undergoing a Vaginal Birth After Cesarean (VBAC)
Status: COMPLETED
Conditions: Duration of Labor
Interventions: DRUG: obsteric gel(k-Y jelly)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Determine the Maximum Tolerated Dose, Safety and Tolerability of a Single Dose of Lanreotide Prolonged Release Formulation (PRF) in Subjects With Acromegaly
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: Lanreotide PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of PF582 Versus Lucentis in Patients With Age Related Macular Degeneration
Status: COMPLETED
Conditions: Age Related Macular Degeneration (AMD)
Interventions: DRUG: Lucentis|DRUG: PF582
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Involving Family to Improve Communication in Breast Cancer Care
Status: COMPLETED
Conditions: Active Breast Cancer Treatment
Interventions: OTHER: Checklist, MyChart, OpenNotes|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The NODE-202 Study (Study of Etripamil Nasal Spray in Pediatric Patients)
Status: RECRUITING
Conditions: Paroxysmal Supraventricular Tachycardia
Interventions: DRUG: Etripamil NS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MM-398 (Nanoliposomal Irinotecan, Nal-IRI) to Determine Tumor Drug Levels and to Evaluate the Feasibility of Ferumoxytol Magnetic Resonance Imaging to Measure Tumor Associated Macrophages and to Predict Patient Response to Treatment
Status: COMPLETED
Conditions: Solid Tumors|ER/PR Positive Breast Cancer|Triple Negative Breast Cancer|Metastatic Breast Cancer With Active Brain Metastasis
Interventions: DRUG: Ferumoxytol|DRUG: MM-398
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Budesonide / Formoterol Combination in Repeated AMP Provocations
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: budesonide/formoterol Turbuhaler|DRUG: formoterol Turbuhaler|DRUG: salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Bowel Cleansing for Colonoscopy: Comparison Between a Same Day Low-Volume Preparation and a Conventional 4L Split One
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: Bisacodyl plus PEG-CS|DRUG: PEG 4 litres split
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Trilinolein Cream for Prevention of Relapse in Remission of Moderate-to-severe Atopic Dermatitis.
Status: NOT_YET_RECRUITING
Conditions: Atopic Dermatitis
Interventions: OTHER: trilinolein cream group|OTHER: cream base group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Gemcitabine + PEGPH20 vs Gemcitabine Alone in Stage IV Previously Untreated Pancreatic Cancer
Status: COMPLETED
Conditions: Stage IV Pancreatic Cancer
Interventions: DRUG: Gemcitabine|DRUG: PEGPH20|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of NT 201 Doses in the Treatment of Platysma Prominence
Status: COMPLETED
Conditions: Platysma Prominence
Interventions: DRUG: NT 201|DRUG: NT 201 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Remimazolam on the Intraoperative Hemodynamics in Bypass Surgery
Status: RECRUITING
Conditions: Intraoperative Hypotension
Interventions: DRUG: Remimazolam|DRUG: Balanced Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety of a Booster Vaccination With a Recombinant Protein RBD Candidate Vaccine Against SARS-CoV-2 in Healthy Adults Volunteers Fully Vaccinated Followed by an Extension Period to Study a Fourth Dose Administration.
Status: COMPLETED
Conditions: COVID-19|SARS-CoV-2 Acute Respiratory Disease
Interventions: BIOLOGICAL: COVID-19 Vaccine HIPRA|BIOLOGICAL: Cominarty (Pfizer-BioNtech)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Filgrastim and Filgrastim SD/01in Boosting White Cell Counts After Intensive Chemotherapy
Status: COMPLETED
Conditions: Ewing's Sarcoma|Rhabdomyosarcoma|MPNST|Synovial Sarcoma|High-risk Sarcoma
Interventions: BIOLOGICAL: Filgrastim|BIOLOGICAL: Filgrastim-SD/01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial in Patients With Diffuse Large-B-cell Lymphoma Comparing Pixantrone Against Doxorubicin
Status: COMPLETED
Conditions: Diffuse Large-Cell Lymphoma
Interventions: DRUG: CPOP-R|DRUG: CHOP-R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Oleanolic Acid Formulated as Functional Olive Oil
Status: COMPLETED
Conditions: Healthy Subjects|Bioavailability
Interventions: DIETARY_SUPPLEMENT: Oleanolic acid (CAS no. 598-02-1; PubChem CID 10494)|DIETARY_SUPPLEMENT: Control commercial olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety Study of MK-3641 and MK-7243 Co-administered in Adult Participants With Ragweed and Grass Pollen Induced Allergic Rhinitis (P08607, MK-3641-006)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: BIOLOGICAL: MK-3641 12 Amb a 1-U (short ragweed extract)|BIOLOGICAL: MK-7243 2800 BAU (Timothy grass extract)|DRUG: Rescue Medication
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Age on Dexmedetomidine Pharmacodynamic
Status: COMPLETED
Conditions: Spinal Anesthesia
Interventions: DRUG: Dexmedetomidine 01|DRUG: Dexmedetomidine 02
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Intravenous Ibuprofen for Treatment of Pain in Pediatric Patients Undergoing Tonsillectomy
Status: COMPLETED
Conditions: Tonsillectomy
Interventions: DRUG: Intravenous ibuprofen|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Attention-Bias Modification Treatment for PTSD
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: BEHAVIORAL: Attention Bias Modification (ABM)|BEHAVIORAL: Attention control training (ACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of rhPTH(1-84) Treatment in Japanese Participants With Chronic Hypoparathyroidism
Status: WITHDRAWN
Conditions: Chronic Hypoparathyroidism
Interventions: DRUG: rhPTH(1-84)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy & Tolerability Between Ganfort vs Krytantek in Mexican Patients With Primary Open-Angle Glaucoma (POAG) or Ocular Hypertension (OHT)
Status: COMPLETED
Conditions: Glaucoma Primary Open Angle
Interventions: DRUG: Ganforti|DRUG: Krytantek
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cf-DNA Assay During Treatment of Acute Rejection
Status: COMPLETED
Conditions: Kidney Transplant Failure and Rejection|Kidney Transplant; Complications|Kidney Transplant Rejection|Transplant; Complication, Rejection|Transplant Dysfunction
Interventions: GENETIC: cf-DNA Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Allogenic Bone Marrow Mesenchymal Stem Cells Infusion in Patients With Steroid-refractory GVHD
Status: COMPLETED
Conditions: Graft Versus Host Disease
Interventions: BIOLOGICAL: Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Outcome After Edoxaban Versus Vitamin K Antagonists for Acute VTE
Status: UNKNOWN
Conditions: Venous Thromboembolic Disease|Post Thrombotic Syndrome|Chronic Thromboembolic Pulmonary Hypertension|Quality of Life
Interventions: OTHER: Observation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oritavancin for Staphylococcus Aureus Infections in Opioid Users
Status: WITHDRAWN
Conditions: Staphylococcus Aureus Bacteremia|Staphylococcus Aureus Endocarditis
Interventions: DRUG: Oritavancin Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: THE TRAVEL TRIAL: Transcatheter Right Atrial-ventricular Valve rEplacement With LuX-Valve
Status: RECRUITING
Conditions: Tricuspid Valve Insufficiency
Interventions: DEVICE: Tricuspid Valve Replacement System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness and Self-Compassion With Caregivers Working With Delinquent Youth
Status: ACTIVE_NOT_RECRUITING
Conditions: Caregivers of Delinquent Youth
Interventions: BEHAVIORAL: Mindfulness and Self-Compassion for Caregivers working in Youth Detention Centres
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of COVID-19 Pandemic and Social Distancing on Mental Health of Chronic Inflammatory Rheumatism Affected Patients
Status: COMPLETED
Conditions: Covid19|Rheumatic Fever|Mental Disorder
Interventions: BEHAVIORAL: Questionnaire|BIOLOGICAL: blood sample and salivary sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 1 Seattle Dietary Biomarkers Development Center
Status: RECRUITING
Conditions: Healthy Adults
Interventions: OTHER: Controlled feeding study of beef and/or pinto beans|OTHER: Controlled feeding study of eggs and/or black beans
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Root Canal Obturation With a Ready-to-use Root Canal Sealer (PA1704) Versus BioRoot™ RCS: a Randomized Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Root Canal Obturation
Interventions: DEVICE: ready-to-use root canal sealer: PA1704|DEVICE: root canal sealer: BioRoot™ RCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics (PK) of Medroxyprogesterone Acetate Following an Injection of TV-46046 in Healthy Women of Reproductive Age
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: TV-46046|DRUG: Depo-subQ Provera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effectiveness of Hemopatch® in the Reduction of Post-surgical Serous Drainage
Status: RECRUITING
Conditions: Hemopatch|Breast Cancer|Axillary Lymphadenectomy
Interventions: DEVICE: Hemopatch|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of Golimumab in Patients With Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Golimumab|DRUG: Golimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topiramate and Prolonged Exposure
Status: COMPLETED
Conditions: PTSD and Alcohol Use Disorder
Interventions: DRUG: topiramate|BEHAVIORAL: prolonged exposure|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Computerized Response Training Obesity Treatment
Status: COMPLETED
Conditions: Obesity|Hyperphagia|Feeding and Eating Disorders
Interventions: BEHAVIORAL: Computer Based Response Training Weight Loss Intervention|BEHAVIORAL: Generic Response Training Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Could Single-anastomosis Gastric Bypass Be a Curative Treatment for Type II Diabetes?
Status: SUSPENDED
Conditions: Metabolic Surgery
Interventions: PROCEDURE: Single-Anastomosis Gastric Bypass surgery (SAGB).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Are Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio, and Systemic Immune Inflammation Score Values Indicators for Postoperative Pain?
Status: COMPLETED
Conditions: Postoperative Pain Status of Patients Who Underwent Elective Laparoscopic Cholecystectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: VAL-1221 Delivered Intravenously in Ambulatory and Ventilator-free Participants With Late-Onset Pompe Disease
Status: TERMINATED
Conditions: Pompe Disease
Interventions: DRUG: VAL-1221|DRUG: RhGAA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperglycemic Profiles in Obstructive Sleep Apnea: Effects of PAP Therapy
Status: COMPLETED
Conditions: Sleep Apnea|Diabetes
Interventions: DEVICE: REMStar Positive Airway Pressure|BEHAVIORAL: LifeStyle Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Augmented Multimodal Neurologic Monitoring in High Risk Survivors of Cardiac Arrest
Status: TERMINATED
Conditions: Cardiac Arrest
Interventions: DEVICE: QFlow 500™ Perfusion Probe (Hemedex, Cambridge, MA)|DEVICE: Spencer Probe Depth Electrode (Ad-Tech Medical, Racine, WI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an Amino Acid Mixture on Gastrointestinal Function, Inflammation and Fluid Balance: A Pilot Study in Patients With Inflammatory Bowel Disease
Status: TERMINATED
Conditions: Inflammatory Bowel Diseases|Short Bowel Syndrome|Ileostomy - Stoma
Interventions: OTHER: amino acid mixture beverage|OTHER: glucose-based sports drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy Study of a Cervical Pessary Containing Progesterone for the Prevention of Preterm Delivery
Status: COMPLETED
Conditions: Preterm Birth
Interventions: DRUG: Progesterone Cervical Pessary 6.3 g|DRUG: Progesterone 200 mg vaginal capsules|DRUG: Progesterone Cervical Pessary 7.7 g
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 1 Study of ART5803 to Assess Safety and Tolerability in Healthy Participants
Status: NOT_YET_RECRUITING
Conditions: Autoimmune Encephalitis
Interventions: DRUG: ART5803
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of Oral Debio 0123 in Combination With Carboplatin in Participants With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: Debio 0123|DRUG: Carboplatin|DRUG: Debio 0123|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 3-fold Crossover Bioequivalence Study Between Glucobay Orally Disintegrating Tablet (ODT) and Glucobay Standard Tablet
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Acarbose (Glucobay ODT, BAYG5421)|DRUG: Acarbose (Glucobay ODT, BAYG5421)|DRUG: Acarbose (Glucobay, BAYG5421)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Tributyrin to Promote Gut Health Among Children Undergoing Hematopoietic Cell Transplantation
Status: WITHDRAWN
Conditions: Hematopoietic Cell Transplantation (HCT)
Interventions: COMBINATION_PRODUCT: Tributyrin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Digital Addiction Among University Students
Status: RECRUITING
Conditions: Internet Addiction|University Student
Interventions: OTHER: Musculoskeletal System Health Questionnaire Scale|OTHER: International Physical Activity Questionnaire (short form)|OTHER: Pittsburgh Sleep Quality Index|OTHER: Cognitive Failures Questionnaire|OTHER: Jamar hand dynamometer|OTHER: Depression Anxiety Stress Scale - 21 Short Form|OTHER: Body Awareness Questionnaire|OTHER: SF-12
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I, Multicenter, Randomized, Double-Blind, Placebo-Controlled HIV-1 Vaccine Trial to Evaluate the Safety and Immunogenicity of Low Dose MN rsgp120/HIV-1 (Genentech) in Combination With QS21 Adjuvant or Alum in Healthy Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: rgp120/HIV-1MN
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of OLOMAX Tab
Status: COMPLETED
Conditions: Hypertension|Dyslipidemias
Interventions: DRUG: OLOMAX 20/5/5mg|DRUG: OLOMAX 20/5/10mg|DRUG: Olmesartan 20 mg/Amlodipine 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH
Status: RECRUITING
Conditions: Genetic Predisposition|Metabolic Diseases|Type 2 Diabetes
Interventions: DRUG: oral semaglutide|OTHER: Mixed Meal Tolerance Test (MMTT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OatMeal and Insulin Resistance: OMA-IR
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2|Insulin Resistance
Interventions: BEHAVIORAL: Diet: carbohydrate days. (Name: oatmeal.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Effect of BMS-791325 on the ECG QTcF Interval in Healthy Subjects
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: BMS-791325|DRUG: Moxifloxacin|DRUG: Placebo matching BMS-791325
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Internal Radiation Therapy With or Without External-Beam Radiation Therapy in Treating Patients With Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: RADIATION: brachytherapy|RADIATION: hypofractionated radiation therapy|RADIATION: image-guided radiation therapy|RADIATION: intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Intervention of Prodromal Schizophrenia Using an NMDA Enhancer
Status: RECRUITING
Conditions: Prodromal Schizophrenia
Interventions: DRUG: NMDAE|DRUG: Placebo Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of a French-language Version of Quality of Life Questionnaires in Patients With Peripheral Facial Palsy
Status: UNKNOWN
Conditions: Peripheral Facial Paralysis|Quality of Life
Interventions: OTHER: Facial disability Index" (FDi)|OTHER: "Facial Clinimetric Evaluation" (FaCE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Switching From Current cART to Triumeq With Adherence Support Will Enhance HIV Control in Vulnerable Populations
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Switch to Triumeq|BEHAVIORAL: Adherence support + current ART
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supportive Treatment and Antibiotics for Mild Pediatric Pneumonia
Status: COMPLETED
Conditions: Pneumonia|Pediatric Respiratory Diseases|Antibiotic Use|Community-acquired Pneumonia
Interventions: DRUG: Supportive Care + Amoxicillin|DRUG: Supportive Care + Placebo (no antibiotics)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Can Exercise Rewire the Brain Addiction Circuitry?
Status: NOT_YET_RECRUITING
Conditions: Physical Exercise
Interventions: BEHAVIORAL: Aerobic Exercise|BEHAVIORAL: Agility-Cognitive Exercise|BEHAVIORAL: Stretching/relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Oxytocin in Obese Adults
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: oxytocin nasal spray|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Juice Plus+OMEGA Study
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: control group|DIETARY_SUPPLEMENT: Omega2|DIETARY_SUPPLEMENT: Omega4|DIETARY_SUPPLEMENT: Omega2+OGV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multicentre LOGIC-Insulin Algorithm-guided Versus Nurse-directed Blood Glucose Control During Critical Illness (LOGIC-2)
Status: COMPLETED
Conditions: Critical Illness|Hyperglycemia|Hypoglycemia
Interventions: DEVICE: LOGIC-Insulin algorithm|DEVICE: Paper protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics of Tenofovir Alafenamide (TAF) in Adults With Normal Hepatic Function and Adults With Severe Hepatic Impairment
Status: COMPLETED
Conditions: Hepatitis B Virus
Interventions: DRUG: TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound, Doppler ,and Calprotectin in Necrotizing Enterocolitis Diagnosis
Status: UNKNOWN
Conditions: Necrotizing Enterocolitis
Interventions: DIAGNOSTIC_TEST: fecal calprotectin , doppler and ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Non-invasive Aortic Aneurysm Tissue Characterization Using Wall Viscoelasticity
Status: RECRUITING
Conditions: Abdominal Aortic Aneurysm Without Rupture
Interventions: DEVICE: Multiphase scan CT, non-invasive vascular ultrasound elastography by ultrasound (NIVE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multicentre Placebo-controlled Double-blinded Phase II Study of Lenvatinib Efficacy in Patients With Locally Advanced or Metastatic GIST (Gastrointestinal Stromal Tumor) After Imatinib/Sunitinib Failure
Status: COMPLETED
Conditions: Gastro Intestinal Stromal Tumour
Interventions: DRUG: Lenvatinib|DRUG: Placebo|OTHER: Best supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Motivation and Skills for Delta-9-tetrahydrocannabinol/Ethanol (THC/ETOH+) Teens in Jail
Status: COMPLETED
Conditions: Alcohol Drinking|Marijuana Smoking
Interventions: BEHAVIORAL: MI/CBT|BEHAVIORAL: RT/SU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Analgesic Effect of Ropivacaine in Topical Use at the Thin Skin Graft Donor Site
Status: UNKNOWN
Conditions: Graft Pain
Interventions: DRUG: 20 mL topically used during alginate dressing NAROPEINE|DRUG: 20 mL topically used during alginate dressing NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surufatinib Combined With Carboplatin/Paclitaxel and Surufatinib Combined With Olaparib as First-line and Maintenance Therapy for Newly Diagnosed High-risk Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serratus Anterior Plane Block for Minimal Invasive Cardiac Surgery
Status: COMPLETED
Conditions: Minimal Invasive Cardiac Surgery|Mitral Valve Surgery|Aortic Valve Replacement|Minimal Invasive Direct Coronary Artery Bypass
Interventions: DRUG: Levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: TRAUMEEL for Pain After Total Knee/Hip Arthroplasty
Status: TERMINATED
Conditions: Total Knee and Total Hip Arthroplasty
Interventions: DRUG: Traumeel S|OTHER: Traumeel S|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AMG 510 Ethnic Sensitivity Study (CodeBreaK 105).
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced/Metastatic Solid Tumors With KRAS p.G12C Mutation
Interventions: DRUG: AMG 510
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Telephonic Monitoring During Inter-treatment Intervals on Emotional State, Quality of Life and Toxicities, on Neo Adjuvant or Adjuvant Chemotherapy-treated Patients
Status: COMPLETED
Conditions: Non-metastatic Patients With Breast Cancer|Non-metastatic Patients With Colon Cancer|Non-metastatic Patients With Rectal Cancer|Patients Undergoing Adjuvant Chemotherapy
Interventions: OTHER: Clinical and psychosocial phone calls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy/Safety of Verteporfin Photodynamic Therapy and Ranibizumab Compared With Ranibizumab in Patients With Subfoveal Choroidal Neovascularization
Status: COMPLETED
Conditions: Macular Degeneration|Choroidal Neovascularization
Interventions: DRUG: Verteporfin Photodynamic Therapy|DRUG: Ranibizumab|DRUG: Verteporfin Placebo|DRUG: Ranibizumab Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring the Comorbidity Between Mental Disorders and General Medical Conditions
Status: COMPLETED
Conditions: Organic, Including Symptomatic, Mental Disorders|Substance Use|Schizophrenia|Mood [Affective] Disorders|Neurotic, Stress-related and Somatoform Disorders|Eating Disorder|Disorders of Adult Personality and Behavior|Mental Retardation|Disorder of Psychological Development|Behavioural Disorder|Hypertension|Dyslipidemias|Ischemic Heart Disease|Atrial Fibrillation|Heart Failure|Peripheral Occlusive Disease|Stroke|Diabetes Mellitus|Thyroid Disorder|Gout|Chronic Pulmonary Disease|Allergy|Chronic Gastritis|Chronic Liver Disease|Inflammatory Bowel Diseases|Diverticular Disease of Large Intestine|Chronic Kidney Diseases|Prostate Disorders|Connective Tissue Disorder|Osteoporosis|Pain|HIV/AIDS|Anemia|Cancer|Vision Disorders|Hearing Disorders|Migraine|Epilepsy|Parkinson Disease|Multiple Sclerosis|Neuropathy
Interventions: OTHER: Organic Disorders|OTHER: Substance Use Disorders|OTHER: Schizophrenia Disorders|OTHER: Mood disorders|OTHER: Neurotic disorders|OTHER: Eating Disorders|OTHER: Personality Disorders|OTHER: Intellectual Disorders|OTHER: Developmental Disorders|OTHER: Behavioral Disorders
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oxcarbazepine Versus Placebo in Childhood Autism
Status: COMPLETED
Conditions: Autism
Interventions: DRUG: Oxcarbazepine|OTHER: Placebo/sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regression of Fatty Heart by Valsartan Therapy
Status: WITHDRAWN
Conditions: Metabolic Syndrome|Lipotoxicity
Interventions: DRUG: Valsartan|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retaining Short-term Training Effects on Gait Adaptability in People With Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: BEHAVIORAL: Gait adaptability training|BEHAVIORAL: Home-based exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of PF-06747143, As Single Agent Or In Combination With Standard Chemotherapy In Adult Patients With Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: PF-06747143|DRUG: Cytarabine|DRUG: Daunorubicin|DRUG: Azacitidine|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Temporary Blood Brain Barrier Disruption in Patients With Parkinson's Disease Dementia
Status: UNKNOWN
Conditions: Parkinsons Disease With Dementia
Interventions: DEVICE: MR Guided Focused Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuropsychiatric Side Effects of Efavirenz in Children Living With HIV
Status: COMPLETED
Conditions: Efavirenz|Child Behavior|Cognitive Symptom|Medication Adherence|Drug-Related Side Effects and Adverse Reactions
Interventions: DRUG: Efavirenz|DRUG: Nevirapine|DRUG: Lopinavir-Ritonavir Drug Combination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Tenecteplase for Restoration of Function in Dysfunctional Hemodialysis (HD) Catheters
Status: COMPLETED
Conditions: Dysfunctional Hemodialysis Catheters
Interventions: DRUG: Tenecteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of Ketorolac Dose on Duration of Analgesia in Emergency Department (ED) Renal Colic Patients
Status: RECRUITING
Conditions: Renal Colic|Flank Pain|Emergencies|Analgesia
Interventions: DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of mAb 216 With Chemotherapy for Treatment of Pediatric Relapsed or Refractory B-progenitor Acute Lymphoblastic Leukemia
Status: TERMINATED
Conditions: Leukemia, Lymphocytic, Acute|Leukemia|Acute Lymphoid Leukemia (ALL)
Interventions: DRUG: Human mAb 216|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: [68Ga]-NeoBOMB1 Imaging in Patients With Malignancies Known to Overexpress Gastrin Releasing Peptide Receptor (GRPR)
Status: TERMINATED
Conditions: Breast Cancer|Prostate Cancer|Colorectal Cancer|Non Small Cell Lung Cancer|Small Cell Lung Cancer
Interventions: DRUG: [68Ga]-NeoBOMB1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Efficacy and Safety of Risperidone Injections Given Once a Month to Adults With Schizophrenia or Schizoaffective Disorder
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorders
Interventions: DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of Artificial Intelligence-based Computer Aided Diagnosis Software That Assists in Determining Whether or Not to Conduct Amyloid PET for the Diagnosis of Alzheimer's Disease by Predicting Amyloid PET Positivity in Mild Cognitive Impairment Patients
Status: COMPLETED
Conditions: Alzheimer Disease|Mild Cognitive Impairment
Interventions: DEVICE: NeuroAI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fluorescence for Sentinel Lymph Node Identification in Cancer Surgery
Status: COMPLETED
Conditions: Breast Carcinoma|Head and Neck Cancer|Melanoma (Skin)|Squamous Cell Carcinoma, Skin|Cervix Cancer|Endometrium Cancer|Ovary Cancer|Vulva Cancer|Anus Cancer|Rectum Cancer
Interventions: DRUG: Indocyanine green|DRUG: Technetium99|DEVICE: Optonuclear probe|DEVICE: Quest Camera
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Music Therapy and Pre-recorded Music on Patients and Caregivers in the Emergency Unit
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Stress|Well-Being, Psychological
Interventions: OTHER: Environmental Music Therapy|OTHER: Pre-recorded music|OTHER: Standard care only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase I/II Trial of Early Infusion of Rapidly-generated Multivirus Specific T Cells (MVST) to Prevent Post Transplant Viral Infections
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia|CML (Chronic Myelogenous Leukemia)|MDS (Myelodysplastic Syndrome)|Acute Lymphoblastic Leukemia|AML (Acute Myelogenous Leukemia)
Interventions: BIOLOGICAL: MVST|BIOLOGICAL: MVSTr
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: N2003-01: Irinotecan, Temozolomide, and Cefixime in Treating Young Patients With Recurrent or Resistant Neuroblastoma
Status: COMPLETED
Conditions: Diarrhea|Drug/Agent Toxicity by Tissue/Organ|Neuroblastoma
Interventions: DRUG: cefixime|DRUG: irinotecan hydrochloride|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of Learning-Theory-Based Smoking Cessation Strategies
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: BEHAVIORAL: Standard treatment|BEHAVIORAL: Standard treatment+practice quitting|DRUG: Very low nicotine cigarettes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real-world Effectiveness of Asciminib and Treatment Patterns in Patients With Chronic Myeloid Leukemia With T315I Mutation - a Chart Review Study of Patients Treated in the Asciminib Managed Access Program (MAP)
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia With T315I Mutation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Vaccine Education Program on Vaccine Advocacy and Vaccine Literacy
Status: NOT_YET_RECRUITING
Conditions: Unrecognized Condition
Interventions: OTHER: Vaccine Education Program Based on Integrated Change Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intra-operative Injection of Autologous Conditioned Plasma (ACP) Following Partial Meniscectomy
Status: COMPLETED
Conditions: Meniscectomy
Interventions: BIOLOGICAL: ACP|OTHER: Standard Meniscectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study сomparing the Efficacy and Safety of RPH-075 and Keytruda® in Patients With Unresectable or Metastatic Skin Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Skin Melanoma
Interventions: DRUG: RPH-075|DRUG: Keytruda®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metastatic Colorectal Cancer Treated With Regorafenib and FOLFIRI
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Regorafenib|GENETIC: UGT1A1 genotyping (TA6/TA6)|GENETIC: UGT1A1 genotyping (TA6/TA7)|GENETIC: UGT1A1 genotyping (TA7/TA7)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraarticular Opioids Vs Glucocorticosteroids in Gonarthritis
Status: UNKNOWN
Conditions: Rheumatic Disease
Interventions: DRUG: intraarticular morphine|DRUG: intraarticular dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Literacy Promotion for Latinos Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Language Development|Behavior, Child|Parenting|Literacy
Interventions: BEHAVIORAL: Usual care including ROR|BEHAVIORAL: Text messages|BEHAVIORAL: Connection to community resources
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Norfloxacin In The Primary Prophylaxis Of Spontaneous Bacterial Peritonitis
Status: COMPLETED
Conditions: Spontaneous Bacterial Peritonitis|Hepatorenal Syndrome|Cirrhosis
Interventions: DRUG: Oral norfloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Early Mobilization Versus Traditional Treatment for Acute Ankle Sprains.
Status: COMPLETED
Conditions: Ankle Sprain
Interventions: OTHER: Jump Stretch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Immunotherapy With Durvalumab and Tremelimumab for Bladder Cancer Patients Ineligible for Cisplatin
Status: TERMINATED
Conditions: Muscle-invasive Bladder Cancer
Interventions: DRUG: Durvalumab (Imfinzi)|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Impact of PENG Block on Quality of Recovery Compared to No-block for Primary Total Hip Arthroplasty
Status: COMPLETED
Conditions: Total Hip Arthroplasty
Interventions: DRUG: PENG Block|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CT for Personalized Mechanical Ventilation
Status: RECRUITING
Conditions: Ventilator-Induced Lung Injury|Sepsis Syndrome|Mechanical Ventilation Complication
Interventions: PROCEDURE: PEEP (positive end-expiratory pressure) - maximum|PROCEDURE: PEEP (positive end-expiratory pressure) - standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION