pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Isa-RVD Study in Patients With Newly Diagnosed Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Isatuximab|DRUG: Bortezomib|DRUG: Lenalidomide|DRUG: Dexamethasone (IV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of Instantaneous Wave-Free Ratio by Computed Tomography
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: PressureWire™ Certus(St. Jude Medical Systems, Sweden)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Abatacept as GVHD Prophylaxis Phase 2
Status: COMPLETED
Conditions: Graft vs Host Disease|Malignancy
Interventions: DRUG: Abatacept|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: IVIG vs SCIG in CIDP
Status: RECRUITING
Conditions: CIDP|Immunoglobulin Deficiency|Chronic Inflammatory Demyelinating Polyneuropathy
Interventions: DRUG: Intravenous immune globulin G|DRUG: Subcutaneous immune globulin G
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Thoracoscopy Versus Fibrinolysis in Children With Empyema
Status: COMPLETED
Conditions: Empyema
Interventions: PROCEDURE: Chest tube with tPA infusion for 3 days|PROCEDURE: VATS decortication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effects of Vibration Therapy on Pain, Functionality, and Proprioception After ACL Injury
Status: COMPLETED
Conditions: Vibration Therapy|Anterior Cruciate Ligament Injuries
Interventions: OTHER: Percussion Massage Group|OTHER: Conventional Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Complicated Parapneumonic Effusion With Fibrinolytic Therapy Versus VATs Decortication
Status: COMPLETED
Conditions: Parapneumonic Effusion|Empyema, Pleural|Coagulopathy
Interventions: PROCEDURE: VATS Decortication|DRUG: Fibrinolytic Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel With Rapid Hormonal Cycling as a Treatment for Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: GnRh (Leuprolide)|DRUG: Testosterone Gel|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of C16TR for Inhalation With Tyvaso® Cohort in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: C16TR|DRUG: Placebo|DRUG: Tyvaso®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Multicenter, Double-blind, Vancomycin-controlled Study to Evaluate the Efficacy of Ethanol Lock Solution for the Curative Treatment of Implantable Venous Access Port Infection Due to Coagulase-negative Staphylococci
Status: UNKNOWN
Conditions: Lock Solution|Catheter Related Blood Stream Infections|Central Venous Catheter Infection|Intravenous Drug Delivery Systems|Coagulase-negative Staphylococci Infection
Interventions: DRUG: Ethanol 40% + Enoxaparine 400UI/ml|DRUG: Vancomycine 5 mg/ml + Héparine 2500UI/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Differences in Exhaled Breath by Using Ion Mobility Spectrometry (IMS) in Subjects Tested for SARS-CoV-2 Infection (COVID-19 Disease)
Status: COMPLETED
Conditions: SARS (Severe Acute Respiratory Syndrome)|Covid19
Interventions: DEVICE: Ion Mobility Spectrometry (IMS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: StereoTactic Arrhythmia Radiotherapy in the NetherLands no. 2
Status: RECRUITING
Conditions: Ventricular Tachycardia|Arrythmia, Cardiac
Interventions: RADIATION: Stereotactic Arrhythmia Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Oral VT-1161 in Patients With Acute Vaginal Candidiasis (Yeast Infection)
Status: COMPLETED
Conditions: Candidiasis, Vulvovaginal
Interventions: DRUG: VT-1161|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Posterior Tibial Nerve Stimulation Vs Desmopressin In Children With Primary Monosymptomatic Nocturnal Enuresis
Status: UNKNOWN
Conditions: Primary Monosymptomatic Nocturnal Enuresis
Interventions: DEVICE: Posterior tibial nerve stimulation|DRUG: Desmopressin Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy, Safety, and Tolerability of Serlopitant for the Treatment of Chronic Pruritus of Unknown Origin
Status: COMPLETED
Conditions: Pruritus
Interventions: DRUG: 5 mg Serlopitant Tablets|DRUG: Matching Placebo Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HEARTPrep: A Virtually-delivered Psychosocial Intervention for Mothers Expecting a Baby With Congenital Heart Disease
Status: RECRUITING
Conditions: Congenital Heart Disease
Interventions: BEHAVIORAL: HEARTPrep
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of KN046 With Chemotherapy in First Line Advanced NSCLC
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: KN046|DRUG: Paclitaxel|DRUG: Pemetrexed|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 6R-BH4 Pulmonary Arterial Hypertension Study
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: sapropterin dihydrochloride (6R-BH4)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Titanium Plates vs CAD/CAM Surgical Splints in Maxillary Repositioning of Orthognathic Surgery
Status: COMPLETED
Conditions: Malocclusion|Abnormalities, Jaw
Interventions: DEVICE: 3D Printing Personalized Titanium Plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tibial and Femoral Components Migration and Adaptive Bone Remodeling After Insertion of Persona® TKA
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteo Arthritis Knee
Interventions: DEVICE: Persona® total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of AEB1102 (Pegzilarginase) in Patients With Arginase I Deficiency
Status: COMPLETED
Conditions: Arginase I Deficiency|Hyperargininemia
Interventions: DRUG: AEB1102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Study of Urelumab and Rituximab in Patients With B-cell Non-Hodgkins Lymphoma
Status: COMPLETED
Conditions: B-Cell Malignancies
Interventions: BIOLOGICAL: Urelumab|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Anti-Ischemic Drug Therapy and Percutaneous Transluminal Angioplasty After Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Ischemia
Interventions: PROCEDURE: Percutaneous coronary angioplasty/intervention (PCI)|DRUG: Anti-ischemic drug therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Culturally-Tailored Approach to Improve Medication Use in Patients With Heart Attacks
Status: COMPLETED
Conditions: Coronary Arteriosclerosis|Myocardial Infarction
Interventions: BEHAVIORAL: Navigation by a health worker|BEHAVIORAL: Information control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Effect of Itraconazole on the Way the Body Absorbs, Distributes, and Gets Rid of ACT-1004-1239 Given as a Single Dose of 10 mg to Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ACT-1004-1239 (10 mg)|DRUG: Itraconazole (200 mg, o.d.)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trial of Enteral Glutamine on Clinical Outcomes in Critically Ill Patients
Status: COMPLETED
Conditions: Critical Illness|Enteral Nutrition|Multiple Organ Failure|Infection Complication|Inflammation
Interventions: DRUG: Glutamin|OTHER: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Emotional Processing Impairments in Individuals With TBI
Status: UNKNOWN
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: Emotional Processing Training|BEHAVIORAL: Placebo Control Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Single Rising Intravenous Doses of BI 44370 BS Solution in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 44370|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Impact of Thermotherapy During Childbirth on Postpartum Perineal Pain (PERISAFE)
Status: UNKNOWN
Conditions: Pelvic Pain
Interventions: DEVICE: Heat therapy|DEVICE: Cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Januse Kinase Inhibition With Filgotinib to Silence Autoreactive B Cells in Rheumatoid Arthritis
Status: NOT_YET_RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Filgotinib|DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Respiratory Mechanics and Metabolic Changes During Low Pressure Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Right Ventricle in Chronic Pressure Overload: Identifying Novel Molecular Targets for Functional Imaging
Status: COMPLETED
Conditions: Chronic Thromboembolic Pulmonary Hypertension
Interventions: PROCEDURE: Right ventricular biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Ramucirumab (IMC-1121B) Therapy and Corrected QT (QTc) Interval Changes
Status: COMPLETED
Conditions: Cancer|Solid Tumor
Interventions: BIOLOGICAL: IMC-1121B|DRUG: Moxifloxacin|DRUG: Diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Tacrolimus Combined With Prednisone Treatment of Idiopathic Membranous Nephropathy and Nephrotic Syndrome
Status: COMPLETED
Conditions: Idiopathic Membranous Nephropathy|Nephrotic Syndrome
Interventions: DRUG: tacrolimus combined with prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allo-HCT MUD for Non-malignant Red Blood Cell (RBC) Disorders: Sickle Cell, Thal, and DBA: Reduced Intensity Conditioning, Co-tx MSCs
Status: COMPLETED
Conditions: Sickle Cell Disease|Thalassemia|Diamond-Blackfan Anemia
Interventions: PROCEDURE: Bone marrow transplantation|BIOLOGICAL: Mesenchymal Stromal Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination 5-FU / Calcipotriene Cream for SCCIS/SCC
Status: RECRUITING
Conditions: Squamous Cell Carcinoma
Interventions: DRUG: Combination topical 5-fluorouracil 5% / calcipotriene 0.005% cream|DRUG: Nourivan Base Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin During Exercise for the PrevenTion of Hypoglycaemia
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Dapagliflozin 10 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: eKISS: Electronic KIOSK Intervention for Safer-Sex
Status: COMPLETED
Conditions: Reproductive Behavior|Contraception|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: eKISS: electronic KIOSK for Safer-Sex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Haemodynamic Effects During Orotracheal Intubation, by Direct or Indirect Laryngoscopy With Airtraq
Status: COMPLETED
Conditions: Orotracheal Intubation
Interventions: DEVICE: orotracheal intubation by direct laryngoscopy|DEVICE: orotracheal intubation by indirect laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison Between Excisional Hemorrhoidectomy and Haemorrhoidal Dearterialisation With Anopexy
Status: COMPLETED
Conditions: Third Degree Hemorrhoids
Interventions: PROCEDURE: Hemorrhoidectomy|PROCEDURE: Hemorrhoidal dearterialization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Boston Scientific OffRoad™ Re-entry Catheter System for Subintimal Recanalization of Chronic Total Occlusions in Femoropopliteal Arteries
Status: COMPLETED
Conditions: Chronic Total Occlusion
Interventions: DEVICE: OffRoad Re-entry Catheter System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Remote Diagnosis and Treatment Strategy of New-onset Insomnia Under the COVID-19 Epidemic
Status: ENROLLING_BY_INVITATION
Conditions: Insomnia|CBT|Depression|Anxiety
Interventions: DEVICE: CBTI online programe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Randomised Trial of Induction Gemcitabine and Cisplatin Versus Gemcitabine, Cisplatin, Pembrolizumab and Bevacizumab (GPPB) in Nasopharyngeal Cancer
Status: NOT_YET_RECRUITING
Conditions: Nasopharyngeal Cancer
Interventions: DRUG: cisplatin and gemcitabine|DRUG: induction chemotherapy cisplatin, gemcitabine, bevacizumab and pembrolizumab.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Triggers of Gastrointestinal Symptoms in IBS Patients
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: Purified gluten|OTHER: Non-purified gluten (containing ATIs)|OTHER: Nocebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Improving Tobacco Treatment Rates for Outpatient Cancer Patients Who Smoke
Status: COMPLETED
Conditions: Cancer|Smoking|Tobacco Use|Nicotine Dependence
Interventions: OTHER: Clinician Nudge|OTHER: Patient Nudge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Reduced Contrast Administration in Contrast-enhanced Spectral Mammography (CESM)
Status: TERMINATED
Conditions: Breast Neoplasm|Contrast-enhanced Spectral Mammography
Interventions: PROCEDURE: CESM with a reduced dose of contrast agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of a Strategy Based on Bacterial DNA Detection to Optimize Antibiotics in Patients With Hospital-acquired Pneumonia
Status: RECRUITING
Conditions: Pneumonia, Ventilator-Associated|Pneumonia, Bacterial
Interventions: OTHER: FilmArray® Pneumonia panel plus|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of INS365 Ophthalmic Solution in Subjects With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: diquafosol tetrasodium (INS365) Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of Neural Correlates of Response to Treatment of PTSD-Associated Impulsive Aggression
Status: UNKNOWN
Conditions: Impulsive Aggression|Posttraumatic Stress Disorder
Interventions: DRUG: Phenytoin|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HD12 for Advanced Stages
Status: COMPLETED
Conditions: Hodgkin´s Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Adriamycin|DRUG: Etoposide|DRUG: Procarbazine|DRUG: Prednisone|DRUG: Vincristine|DRUG: Bleomycin|PROCEDURE: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of the Screen of Cancer Survivorship - Occupational Therapy Services (SOCS-OTS) Tool for Use in a Physical Medicine Rehabilitation Clinic
Status: NOT_YET_RECRUITING
Conditions: Cancer|Occupational Therapy
Interventions: OTHER: Screen of Cancer Survivorship - Occupational Therapy Services (SOCS-OTS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Enteric-Coated Mycophenolate Sodium (EC-MPS) Plus Reduced-dose Cyclosporine Microemulsion (CsA-ME) Compared to EC-MPS Plus Standard Dose CsA-ME in Eldery de Novo Renal Transplant Recipients Treated With Basiliximab and Short-term Steroids
Status: COMPLETED
Conditions: Denovo Renal Transplantation
Interventions: DRUG: Enteric-Coated Mycophenolate Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial of Personalized Acupuncture, Fixed Acupuncture, Letrozole and Placebo on Live Birth in Women With PCOS
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: OTHER: Acupuncture|DRUG: Letrozole|DRUG: Placebo letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sphenopalatine Ganglion Block for Postdural Puncture Headache in the Emergency Department
Status: WITHDRAWN
Conditions: Postdural Puncture Headache
Interventions: PROCEDURE: Sphenopalatine Ganglion Block|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The NO-ALS Study: A Trial of Nicotinamide/Pterostilbene Supplement in ALS.
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DIETARY_SUPPLEMENT: EH301 (Nicotinamide Riboside/Pterostilbene)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Blood Stem Cell Transplant for Sickle Cell Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Sickle Cell Disease|Sickle Cell Disorder|Hemoglobinopathies|Thalassemia|Anemia, Sickle Cell
Interventions: DRUG: Cyclophosphamide|DRUG: Pentostatin|DRUG: Rabbit anti-thymocyte globulin|DRUG: Tacrolimus|DRUG: Mycophenolate mofetil|BIOLOGICAL: CD4+ T-cell-depleted Haploidentical Hematopoietic Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TBI Using IMRT and Cyclophosphamide Prior to Stem Cell Transplant for the Treatment of Severe Systemic Sclerosis
Status: RECRUITING
Conditions: Systemic Scleroderma
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Cyclophosphamide|RADIATION: Intensity-Modulated Radiation Therapy|PROCEDURE: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fenoldopam and Splanchnic Perfusion During Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Cardiac Complications|Cardiopulmonary Bypass
Interventions: DRUG: Fenoldopam mesilate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic and Pharmacodynamic Study of S-1 in Patients With Digestive Organ Cancer
Status: UNKNOWN
Conditions: Gastric Cancer|Esophageal Cancer|Pancreatic Cancer|Colon Cancer
Interventions: DRUG: S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Home-based Dementia Care Coordination for Medicare-Medicaid Dual Eligibles in Maryland
Status: COMPLETED
Conditions: Dementia|Caregiver Burden
Interventions: BEHAVIORAL: MIND at Home-Plus Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study Comparing Denosumab With Standard Treatment in Urothelial Cancer Patients With Bone Metastases
Status: COMPLETED
Conditions: Urothelial Carcinoma|Kidney Cancer|Ureter Cancer|Bladder Cancer
Interventions: DRUG: Denosumab|OTHER: Denosumab Placebo|DRUG: Gemcitabine|DRUG: Carboplatin|DRUG: Cisplatin|DIETARY_SUPPLEMENT: Calcium|DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Volume Guarantee-High Frequency Oscillatory Ventilation on Cerebral Blood Flow in Neonates
Status: NOT_YET_RECRUITING
Conditions: Infant, Premature, Diseases|Respiratory Tract Diseases|Cerebral Blood Flow
Interventions: DEVICE: High Frequency Oscillatory Ventilation with Volume Guarantee (SLE6000;SLE)|DEVICE: High Frequency Oscillatory Ventilation (SLE6000;SLE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Intracavernous Injection of Autologous Mesenchymal Stem Cells in the Treatment of Erectile Dysfunction Resistant to Oral Treatment in Patients With Type I Diabetes
Status: UNKNOWN
Conditions: Erectile Dysfunction|Stem Cells|Diabetes Mellitus, Type 1
Interventions: DRUG: Autologous Bone Marrow derived Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Evaluation of Patient Education Efficacy in Pharmacy of National Taiwan University Hospital
Status: COMPLETED
Conditions: Infection
Interventions: OTHER: Reading the package insert of the drug|OTHER: Reading the education information provided by the Pharmacy of NTUH|OTHER: Oral education provided by the pharmacist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Sugammadex Versus Neostigmine on Postoperative Pulmonary Complications
Status: COMPLETED
Conditions: Postoperative Complications|Neuromuscular Blockade
Interventions: DRUG: Sugammadex|DRUG: Neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A One Visit Follow Up of Adults With Fabry Disease Who Started Long-term Enzyme Replacement Therapy As Children
Status: UNKNOWN
Conditions: Quality of Life|Renal Insufficiency|Cardiac Event
Interventions: OTHER: General and Neurological examination|OTHER: Vital signs|PROCEDURE: 12 lead electrocardiogram|PROCEDURE: Echocardiogram|PROCEDURE: Blood draw|PROCEDURE: Urine collection|PROCEDURE: 2-hour Holter Monitor|OTHER: Brief Pain Inventory questionnaire|OTHER: Quality of Life questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety Study of a Refrigerator-stable Formulation of VARIVAX®
Status: COMPLETED
Conditions: Varicella|Measles|Mumps|Rubella
Interventions: BIOLOGICAL: VARIVAX®|BIOLOGICAL: M-M-RTM II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose:
Clinical trial: A Study to Assess the Safety and Efficacy of ASP4345 as Add-on Treatment for Cognitive Impairment in Subjects With Schizophrenia on Stable Doses of Antipsychotic Medication
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: ASP4345|DRUG: placebo|DRUG: risperidone|DRUG: quetiapine|DRUG: olanzapine|DRUG: ziprasidone|DRUG: aripiprazole|DRUG: brexpiprazole|DRUG: paliperidone|DRUG: lurasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fiber to Reduce Colon Cancer in Alaska Native People
Status: COMPLETED
Conditions: Colon Cancer
Interventions: DIETARY_SUPPLEMENT: 70g of fully digestible starch amylopectin corn starch|DIETARY_SUPPLEMENT: Resistant starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Therapeutic Efficacy of Oral L-Ornithine-L-Aspartate on Minimal Encephalopathy
Status: UNKNOWN
Conditions: Hepatic Encephalopathy
Interventions: DRUG: L-ornithine-L-aspartate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TTYP01 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Adult Subjects
Interventions: DRUG: TTYP01 single ascending doses|DRUG: Placebo|DRUG: TTYP01, 60 mg|DRUG: TTYP01, 120 mg|DRUG: Radicut® (ampoule), 30 mg|DRUG: Radicut® (bag) , 60 mg|DRUG: TTYP01, up to 120 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bacterial Lysate In Preventing Asthma
Status: RECRUITING
Conditions: Respiratory Tract Infections|Pediatric Respiratory Diseases|Wheezing
Interventions: DRUG: Bacterial Lysate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: K301 for the Treatment of Seborrhoeic Eczema (SE) of the Scalp
Status: COMPLETED
Conditions: Seborrhoeic Eczema of the Scalp
Interventions: DRUG: K301|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Subcutaneous Progesterone and Vaginal Progesterone for Luteal Phase Support
Status: COMPLETED
Conditions: Progesterone
Interventions: DRUG: subcutaneous progesterone|DRUG: vaginal progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Plant-Based Dietary Intervention in Type 2 Diabetes-2
Status: SUSPENDED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Low-fat, low-Glycemic Index, vegan diet|BEHAVIORAL: ADA diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of AdV-tk + Prodrug Therapy in Combination With Radiation Therapy for Pediatric Brain Tumors
Status: COMPLETED
Conditions: Malignant Glioma|Recurrent Ependymoma
Interventions: BIOLOGICAL: AdV-tk|DRUG: valacyclovir|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation Study on RENEW's Aingeal at KK Women's and Children's Hospital
Status: COMPLETED
Conditions: Vital Sign|Heart Rate|Respiratory Rate
Interventions: OTHER: Heart rate monitoring|OTHER: Respiratory rate monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Changes in Intestinal Permeability 4 Hours After Gluten Challenge
Status: COMPLETED
Conditions: Celiac Disease|Wheat Hypersensitivity|Gluten Sensitivity|Gluten Enteropathy|Immune System and Related Disorders|Duodenal Diseases
Interventions: DIETARY_SUPPLEMENT: Gluten|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Building Resilience in Cyberbullying Victims
Status: COMPLETED
Conditions: Cyberbullying|Depression|Non Suicidal Self Injury|Social Anxiety|Eating Disorders
Interventions: BEHAVIORAL: Wise Intervention (SA, ITP and resilience)|BEHAVIORAL: Standard preventive intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study of Regorafenib in Participants Who Have Been Treated in Previous Bayer-sponsored Regorafenib Studies That Have Been Completed
Status: COMPLETED
Conditions: Solid Cancer
Interventions: DRUG: BAY73-4506 (Regorafenib, Stivarga)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CEM to Reduce Biopsy Rates for Less Than Highly Suspicious Breast Abnormalities: a Prospective Study
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DEVICE: contrast enhanced mammography|DRUG: Iodinated Contrast Media (ICM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Unpinning Termination Therapy for VT/VF
Status: TERMINATED
Conditions: Ventricular Tachycardia|Ventricular Fibrillation
Interventions: DEVICE: Unpinning Termination Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Efficacy of High-intensity Laser Acupuncture in Patients With Chronic, Non-specific Low Back Pain
Status: RECRUITING
Conditions: Chronic Nonspecific Low-back Pain
Interventions: DEVICE: high-intensity laser acupuncture and Exercise therapy program|OTHER: Sham laser acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Placement of Superficial Erector Spinae Plane Block; A New Approach in Spine Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Spine Deformity|Spine Injury|Spine Fracture|Spine Malformation
Interventions: PROCEDURE: superficial erector spina plane block|PROCEDURE: Standard (opioid-based) analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions
Status: RECRUITING
Conditions: In-Stent Restenosis|Cardiovascular Diseases|Coronary Artery Disease
Interventions: DEVICE: Sirolimus Drug Coated Balloon|DEVICE: Plan balloon Angioplasty (POBA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NEOBIFI: Clinical Trial for the Prevention and/or Reduction of the Incidence of Colics in Infants
Status: COMPLETED
Conditions: Colic, Infantile|Probiotic|Gut Microbiome|Bifidobacterium Breve
Interventions: DRUG: Bifidobacterium breve BR03 and Bifidobacterium breve B632|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Endothelin- and Nitric Oxide-system in the Regulation of Optic Nerve Head Blood Flow During Changes in Ocular Perfusion Pressure
Status: WITHDRAWN
Conditions: Ocular Physiology|Optic Disk|Regional Blood Flow
Interventions: DRUG: NG-monomethyl-L-arginine (L-NMMA)|DRUG: Endothelin-1 (ET-1)|DRUG: Physiologic saline solution (placebo control)|DEVICE: Laser Doppler flowmetry|DEVICE: Goldmann applanation tonometer|DEVICE: HP-CMS patient monitor|PROCEDURE: Suction cup method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recombinant Anti-tumor and Anti-virus Protein for Injection Plus Xeloda in Treatment of Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Novaferon|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding the Challenges, Behavioral Patterns, and Preferences Towards Participation in Clinical Trials in Minority Patient Populations for the Development of a Personalized Clinical Trial Educational Platform to Increase Participation in Clinical Trials Among Underserved Cancer Patients
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Best Practice|OTHER: Educational Intervention|OTHER: Electronic Health Record Review|BEHAVIORAL: Patient Navigation|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Liver Transplantation With Tregs at MGH
Status: ACTIVE_NOT_RECRUITING
Conditions: Liver Transplant
Interventions: BIOLOGICAL: arTreg-CSB|PROCEDURE: leukapheresis|DRUG: cyclophosphamide|DRUG: mesna|DRUG: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Oxycodone/Naloxone in Korean Patients With Chemotherapy-Induced Peripheral Neuropathy (CIPN)
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Targin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 68Ga-HA-DOTATATE PET/CT in Adults With Neuroendocrine Tumors
Status: RECRUITING
Conditions: Neuroendocrine Tumors (NET)
Interventions: DIAGNOSTIC_TEST: 68Ga-HA-DOTATATE PET/CT imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability and Pharmacokinetic and Pharmacodynamic Characteristics of Explorative Formulations of Insulin Degludec and IDegAsp 50 in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: insulin degludec|DRUG: placebo|DRUG: insulin degludec/insulin aspart 50
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metacognitive Self Control and Job Interview Training
Status: ENROLLING_BY_INVITATION
Conditions: Self-Control|Recidivism
Interventions: BEHAVIORAL: Metacognitive Self-Control Training (MCT)|BEHAVIORAL: Virtual Reality Job Interview Training (VR-JIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Adrenal Artery Ablation and Spironolactone in Patients With Primary Aldosteronism
Status: RECRUITING
Conditions: Primary Aldosteronism|Hypertension
Interventions: PROCEDURE: Endovascular chemical Ablation of Adrenal Gland
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing a Pipeline to Employ RNA-Seq as a Complementary Diagnostic Tool in Rare Diseases
Status: RECRUITING
Conditions: Atypical Hemolytic Uremic Syndrome|Membranoproliferative Glomerulonephritis|Autosomal Dominant Polycystic Kidney|Healthy
Interventions: PROCEDURE: Skin biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Short Term Effectiveness Study of Juxta-Fit Versus Trico Bandages in the Treatment of Leg Lymphedema
Status: COMPLETED
Conditions: Lymphedema
Interventions: OTHER: bandaging with trico as active controller
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Of Outcomes After Knee Arthroplasty Using Posterior-Substituting Versus Cruciate-Retaining Prostheses
Status: ACTIVE_NOT_RECRUITING
Conditions: Total Knee Arthroplasty
Interventions: PROCEDURE: posterior cruciate ligament-retaining prostheses|PROCEDURE: posterior cruciate ligament-substituting prostheses
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lactobacillus Johnsonii or White Pomegranate Extract on the Vaginal Health
Status: RECRUITING
Conditions: Vaginitis Bacterial|Inflammation, Ear
Interventions: DIETARY_SUPPLEMENT: Lactobacillus johnsonii, Placebo Comparator: White pomegranate extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I Randomized Trial to Evaluate the Safety and Immunogenicity of Vaccinia-HIV Envelope Recombinant Vaccine (HIVAC-1e) in Combination With Soluble Recombinant Envelope Vaccine (VaxSyn)
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: HIVAC-1e|BIOLOGICAL: gp160 Vaccine (MicroGeneSys)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Efficacy and Safety Study of shRNA-modified CD34+ Cells in HIV-infected Patients.
Status: UNKNOWN
Conditions: HIV Infections|AIDS
Interventions: BIOLOGICAL: shRNA-modified CD34+ cells|DRUG: Low dose busulfan preconditioning|DRUG: Busulfan preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Safety, Immunogenicity and Efficacy of VLPM01 in Healthy, Malaria-Naïve Volunteers
Status: COMPLETED
Conditions: Malaria,Falciparum
Interventions: BIOLOGICAL: 5 microgram VLPM01|BIOLOGICAL: 15 microgram VLPM01|BIOLOGICAL: 30 microgram VLPM01|OTHER: Plasmodium falciparum challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of GNC-035, a Tetra-specific Antibody, in Participants With Locally Advanced or Metastatic Solid Tumors
Status: WITHDRAWN
Conditions: Breast Cancer|Solid Tumor
Interventions: DRUG: GNC-035
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Xamiol® Gel Compared to Calcipotriol Scalp Solution in Patients With Scalp Psoriasis
Status: COMPLETED
Conditions: Scalp Psoriasis
Interventions: DRUG: Xamiol® gel|DRUG: Calcipotriol scalp solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of an Inactivated Influenza Vaccine (Split Virus, Vero Cell Derived) in Adults Aged 50 Years and Older
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Vero cell derived, trivalent, seasonal influenza vaccine|BIOLOGICAL: Licensed egg-derived, trivalent seasonal influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Endoscopic Resection of Non-ampullary Duodenal Adenomas: Endoscopic Mucosal Resection (EMR) vs. Endoscopic Full-thickness Resection With the 'Duodenal Full-thickness Resection Device' (dFTRD)
Status: UNKNOWN
Conditions: Duodenal Adenoma
Interventions: PROCEDURE: dFTRD|PROCEDURE: EMR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Antimicrobial Action of Sodium Hypochlorite and Polyhexamethylene Biguanide as Root Canal Irrigants
Status: COMPLETED
Conditions: Irreversible Pulpitis
Interventions: DRUG: Polyhexamethylene biguanide|DRUG: Sodium Hypochlorite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-escalation Trial of Stereotactic Ablative Body Radiotherapy for Non-spine Bone & Lymph Node Oligometastates
Status: COMPLETED
Conditions: Metastatic Cancer
Interventions: RADIATION: Stereotactic Ablative Radiotherapy (SABR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Pilot Study of Methods for Identifying Patients at High Risk of Worsening in the Adult Emergency Department
Status: RECRUITING
Conditions: Non-traumatic Medical Emergency
Interventions: OTHER: FRENCH grid (classification for emergency nurses in French hospitals)|OTHER: QuickSOFA|OTHER: Capillary lactate assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Glycemic Control of Biphasic Insulin Aspart 30 in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 30|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Multiple Biomarkers to Estimate Risk of Ovarian Cancer in Patients With a Pelvic Mass.
Status: COMPLETED
Conditions: Ovarian Neoplasms
Interventions: PROCEDURE: Pelvic imaging|PROCEDURE: Blood draw|PROCEDURE: laparotomy or laparoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Non-integrated Costs Increase Effectiveness of Incentives
Status: COMPLETED
Conditions: Control - No Incentive for Flu Vaccine|Direct Incentive|Indirect Incentive
Interventions: BEHAVIORAL: Email Message|BEHAVIORAL: Incentive for Vaccination|BEHAVIORAL: Incentive for completing a short survey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of Two Monthly Contact Lenses
Status: COMPLETED
Conditions: Refractive Errors
Interventions: DEVICE: Comfilcon A with Digital Zone Optics™ contact lenses|DEVICE: Comfilcon A contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vulvar Lichen Sclerosus: Comparison Between Clobetasol Propionate, Photodynamic Therapy and Low-Intensity Laser
Status: COMPLETED
Conditions: Vulvar Lichen Sclerosus
Interventions: DRUG: Clobetasol propionate|RADIATION: Photodynamic therapy|RADIATION: Low level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Followed By Filgrastim or Sargramostim in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: sargramostim|DRUG: cytarabine|DRUG: mitoxantrone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Analytical Validation of the abioSCOPE Device With an IgE Test Panel: Point-of-Care Precision, Sample Type Comparison and Method Correlation
Status: WITHDRAWN
Conditions: Allergy|Allergic Asthma|Allergy to Cats|Allergy to House Dust|Allergy to Dog Dander (Finding)|Allergy Mold|Allergy Cockroach
Interventions: DEVICE: Blood Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p