pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Codman Catheter/Synchromed Pump Hepatic Artery Chemotherapy for Unresectable Colorectal Metastases/Intrahepatic Cholangiocarcinoma
Status: TERMINATED
Conditions: Bile Duct Neoplasms|Colorectal Neoplasms
Interventions: DEVICE: Hepatic artery infusion pump placement using the Synchromed II pump and the Codman tapered arterial catheter.|DRUG: Hepatic artery infusion pump floxuridine and dexamethasone|DRUG: Systemic chemotherapy for colorectal liver metastases|DRUG: Systemic chemotherapy for intrahepatic cholangiocarcinoma
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Preliminary Efficacy of Acceptance and Commitment Therapy (ACT) for Sleep Disturbances in Adults With Sickle Cell Disease (SCD)
Status: RECRUITING
Conditions: Sickle Cell Disease|Sickle Cell Anemia|Insomnia|Sleeplessness|Transient Insomnia|Nonorganic Insomnia|Chronic Insomnia
Interventions: BEHAVIORAL: ACT Intervention|BEHAVIORAL: Waitlist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vitamin D Treatment to Patients Suffering From Chronic Pain and Vitamin D Hypovitaminosis
Status: COMPLETED
Conditions: Back Pain|Hypovitaminosis D
Interventions: DRUG: Vitamin D|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Throwers Ten Exercises On Upper Extremity Function and Explosive Power in Wheelchair Basketball and Basketball Players
Status: COMPLETED
Conditions: Upper Extremity Injury|Sport Injury|Shoulder Pain|Muscle Weakness
Interventions: OTHER: The effect of throwers ten exercise programme on wheelchair basketball and ambulant basketball players
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Donor-Derived Ex-Vivo Expanded Natural Killer Cell Infusions in Children and Young Adults With High Risk Acute Myeloid Leukemia Receiving Myeloablative HLA-Haploidentical Hematopoietic Cell Transplant
Status: ENROLLING_BY_INVITATION
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Donor-Derived Ex-Vivo Expanded Natural Killer Cell Infusions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Dose Escalation Trial of ASG-5ME in Pancreatic or Gastric Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Neoplasms|Pancreatic Neoplasms
Interventions: DRUG: ASG-5ME
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing STAR and TexSTAR: A Video and Text Messaging Intervention
Status: NOT_YET_RECRUITING
Conditions: Sexual Violence|Posttraumatic Stress Disorder|Opioid Use|Opioid Misuse
Interventions: BEHAVIORAL: Skills Training in Active Recovery (STAR) Video|BEHAVIORAL: Text Skills Training in Active Recovery (TextSTAR) program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Inflammatory Pain and Central Sensitization - A Pilot Study
Status: COMPLETED
Conditions: Pain|Inflammation
Interventions: DEVICE: Electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of MP-513 in Combination With Sulfonylurea in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Placebo / Teneli (Teneligliptin) + SU (Sulfonylurea)|DRUG: Teneli / Teneli + SU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Drug-drug Interaction and Safety of RLD2301 and RLD2007 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: RLD2301|DRUG: RLD2007
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gefitinib in Treating Patients With Persistent or Recurrent Endometrial Cancer
Status: COMPLETED
Conditions: Recurrent Uterine Corpus Carcinoma
Interventions: DRUG: Gefitinib|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Topical Verapamil in Chronic Rhinosinusitis With Nasal Polyps
Status: TERMINATED
Conditions: Sinusitis|Nasal Polyps
Interventions: DRUG: Verapamil Hydrochloride Intranasal
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of FLURBIPROFEN 100 mg FAMOTIDINE 20 mg MULTI-LAYER TABLET in Healthy Subjects Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: FLURBIPROFEN 100 mg FAMOTIDINE 20 mg MULTI-LAYER TABLET|DRUG: ANTADYS® 100 mg, PEPCID® 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: EMERALD: Effects of Metformin on Cardiovascular Function in Adolescents With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dovitinib (TKI258) and Abiraterone Acetate in Metastatic Castrate-Resistant Prostate Cancer (mCRPC)
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Dovitinib|DRUG: Abiraterone Acetate|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Fostamatinib in Subjects With Impaired Kidney Function
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Renal Impairment
Interventions: DRUG: fostamatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: CONcussion Treatment After Combat Trauma (CONTACT)
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: Individualized Scheduled Telephone Support (ISTS)|OTHER: Usual Care (UC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study of the NUVANCE Facial Rejuvenation System for Mid-Face, Neck and Jowl Rejuvenation Procedures
Status: TERMINATED
Conditions: Ptosis of the Neck, Mid-face and/or Jowl
Interventions: DEVICE: NUVANCE Facial Rejuvenation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of a Sutureless Amniotic Membran Transplantation to Treat Ocular Surface Disorders (Expanded Access)
Status: COMPLETED
Conditions: Corneal Ulcers|Corneal Melting
Interventions: DEVICE: Amniotic membrane ring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thoracic Paravertebral Block Using Ropivacaine and Dexmedetomidine
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Video-assisted Pneumonectomy|PROCEDURE: Thoracic paravertebral block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trails of Photoelectrochemical Immunosensor for Early Diagnosis of Acute Myocardial Infarction
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: Graphene quantum dots combined with Si nanowire photoelectrochemical immunosensor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial of SHR3680 in Prostate Cancer Patients Who Are Candidates for Radical Prostatectomy
Status: RECRUITING
Conditions: Patients With High-risk Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy
Interventions: DRUG: SHR3680|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Different Anesthetic Approaches for Intravitreal Injections
Status: COMPLETED
Conditions: Pain
Interventions: PROCEDURE: Group Drops|PROCEDURE: Group SC|PROCEDURE: Group gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Role of the Device Operating Under the Continuous Positive Airway Pressure in the Recovery Process of Cochlea
Status: RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: DEVICE OPERATING UNDER THE CONTINOUS POSITIVE AIRWAY PRESSURE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Thoracic Spinal Versus Epidural Anesthesia for Nephrectomy in Obstructive/Restrictive Lung Disease Patients
Status: COMPLETED
Conditions: Nephrectomy|Lung Diseases|Anesthesia
Interventions: PROCEDURE: Thoracic Spinal Anesthesia|PROCEDURE: Thoracic Epidural Anesthesia|DRUG: Bupivacaine 0.5% (hyperbaric)|DRUG: Bupivacaine 0.5% (isobaric)|DRUG: Fentanyl|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: High Dose Oral 4-Aminosalicylic Acid (PASER®) to Control Acute Flares of Mild to Moderate Crohn's Disease
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DRUG: 4-Aminosalicylic acid|DRUG: PASER placebo granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stroke Telemedicine Outpatient Prevention Program for Blood Pressure Reduction
Status: COMPLETED
Conditions: Stroke Prevention|Blood Pressure|Telemedicine|Psychosocial Impairment
Interventions: BEHAVIORAL: Educational Packet|BEHAVIORAL: Phone call at 72 hours by discharge nurse navigator|BEHAVIORAL: Telehealth visit at 7 days, 1 month, 3 months, and 5 months after discharge|BEHAVIORAL: Educational messages every other week|DIAGNOSTIC_TEST: BP monitoring by QardioARM with periodic transmission of BP data
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surface Nerve Stimulation Treatment for OAB in Children
Status: COMPLETED
Conditions: Overactive Bladder|Urinary Incontinence
Interventions: DEVICE: Nerve stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of IV Acetaminophen in Tonsillectomies
Status: COMPLETED
Conditions: Adenotonsillitis|Tonsillitis
Interventions: DRUG: Acetaminophen (paracetamol)|DRUG: Normal Saline Flush|DRUG: Midazolam|DRUG: Sevoflurane|DRUG: Nitrous Oxide/Oxygen|DRUG: Propofol|DRUG: Morphine|DRUG: Ondansetron|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of 3 Dimensional Laparoscopic System in Disral Pancreatectomy and Splenectomy
Status: COMPLETED
Conditions: Benign Neoplasm of Body of Pancreas|Benign Neoplasm of Tail of Pancreas
Interventions: DEVICE: 3-dimensional distal pancreatectomy|DEVICE: 2-dimensional distal pancreatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Systematic Approach for the Diagnosis and Treatment of Obstructive Lung Diseases
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease|Asthma|Overlap Syndrome
Interventions: DRUG: LABA + LAMA|DRUG: ICS|DRUG: LABA + LAMA + ICS|DRUG: LABA + ICS|DRUG: other
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Sitagliptin Compared With Glimepiride in Elderly Participants With Type 2 Diabetes Mellitus (MK-0431-251)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: sitagliptin phosphate|DRUG: Glimepiride|DRUG: Placebo to Sitagliptin|DRUG: Placebo to Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Fatty Acid Delivery on Heart Metabolism and Function in Type 2 Diabetes (T2DM
Status: COMPLETED
Conditions: Diabetes Mellitus, Type II
Interventions: DRUG: Metformin|DRUG: Rosiglitazone|DRUG: Lovaza
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Sacroiliac Joint Radiofrequency Ablation: A Pilot Study
Status: COMPLETED
Conditions: Sprain of Sacroiliac Ligament|Low Back Pain|Osteoarthritis Nos, of Sacroiliac Joint
Interventions: PROCEDURE: Radiofrequency ablation|PROCEDURE: Sensory block|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Gold Fish Exercises and Cervico-thoracic Postural Correction Training in Patients With TMJD
Status: COMPLETED
Conditions: Temporomandibular Joint|Temporomandibular Joint Dysfunction
Interventions: OTHER: Gold Fish exercises|OTHER: Cervico-thoracic postural correction training|OTHER: Conventional PT treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Transmuscular Quadratus Lumborum Block for Elective Laparoscopic Hand-assisted Nephrectomy and Robot Assisted Partiel Nephrectomy
Status: COMPLETED
Conditions: Postoperative Pain|Ultrasound Guided Transmuscular Quadratus Lumborum Block
Interventions: DRUG: Ropivacaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of SyB L-0501 for Patients With Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: SyB L-0501|DRUG: prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Chemoradiotherapy Versus Chemotherapy Alone in Nonsmall Cell Lung Cancer (NSCLC) Patients With Mediastinal Lymph Node Metastases
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: RADIATION: neoadjuvant chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Outcomes of Intracavernosal Umbilical Cord Mesenchymal Stem Cells Implantation in Patients With Diabetic Erectile Dysfunction
Status: UNKNOWN
Conditions: Urologic Diseases|Erectile Dysfunction With Diabetes Mellitus
Interventions: BIOLOGICAL: stem cells|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Different Pramipexole Slow-release Formulations Compared to Immediate-release Tablet in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Formulation B: Pramipexole Slow release (SR) tablet|DRUG: Formulation C: Pramipexole Slow release tablet|DRUG: Formulation D: Pramipexole Slow release tablet|DRUG: Formulation E: Pramipexole Slow release tablet|DRUG: Formulation F: Pramipexole Slow release tablet|DRUG: Formulation G: Pramipexole Slow release tablet|DRUG: Formulation H: Pramipexole Slow release tablet|DRUG: Pramipexole immediate release (IR) tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Roux-en-Y Gastric Bypass Versus Loop Gastrojejunostomy for Malignant Gastric Outlet Obstruction
Status: RECRUITING
Conditions: Malignant Gastric Outlet Obstruction
Interventions: PROCEDURE: Roux-en-Y Bypass|PROCEDURE: gastrojejunostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of GSK Biologicals' Influenza Vaccine Versus a Licensed Comparator in Children
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluarix|BIOLOGICAL: Fluzone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Laser In Situ Fenestration Study
Status: NOT_YET_RECRUITING
Conditions: Aortic Aneurysm|Endovascular Aneurysm Repair
Interventions: DEVICE: Fenestrated Endovascular Aneurysm Repair using the LIFE Device System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Monitoring of Energy Expenditure, Dynamic Stability and Fatigue During Gait in Patients With Cerebellar Ataxia Gene
Status: COMPLETED
Conditions: Cerebellar Ataxia
Interventions: OTHER: Longitudinal Monitoring of Energy Expenditure, Dynamic Stability and Fatigue During Gait|OTHER: walking track GAITRite,manual dynamometer, and treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of HC-7366 With Azacitidine and Venetoclax for Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: HC-7366|DRUG: Azacitidine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Painful Real-life Experience of the Child of Less Than Three Years During the Removal of the Collecting Bags in the Pediatric Urgency: What Strategy of Coverage?
Status: COMPLETED
Conditions: Urinary Infection
Interventions: OTHER: Oiled-limestone liniment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Physical Inactivity on Insulin Sensitivity, Appetite, Energy Balance, and Cardiovascular Responses in Humans.
Status: COMPLETED
Conditions: Sedentary Behavior
Interventions: OTHER: Control|OTHER: SIT+E|OTHER: SIT=E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Caudal and Penile Block on Hypospadias Repair Complications
Status: COMPLETED
Conditions: Hypospadias
Interventions: PROCEDURE: Caudal block anesthesia|PROCEDURE: Dorsal penile nerve block anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Mitoxantrone Hydrochloride Liposome Injection vs. Chidamide in Patients With Relapsed/Refractory PTCL
Status: NOT_YET_RECRUITING
Conditions: Peripheral T Cell Lymphoma
Interventions: DRUG: Mitoxantrone Hydrochloride Liposome Injection|DRUG: Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Effect of a Probiotic Mixture in the Treatment of Atopic Dermatitis in Children
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DIETARY_SUPPLEMENT: Probiotic mixture with three bacterial strains with maltodextrin as a carrier.|OTHER: Placebo comparator with maltodextrin as a carrier.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Pancreatic Duct Stenting for Relief of Obstructive Pain in Patients With Pancreatic Cancer
Status: WITHDRAWN
Conditions: Pancreatic Cancer
Interventions: DEVICE: Pancreatic Duct Stent Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Remote Ischemic Conditioning on Trauma Patients With Hemorrhagic Shock
Status: COMPLETED
Conditions: Hemorrhagic Shock
Interventions: DEVICE: Pneumatic tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatments for COVID-19: Canadian Arm of the SOLIDARITY Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: DRUG: Artesunate|DRUG: Imatinib|DRUG: Infliximab|DRUG: Dexamethasone|DRUG: LSALT Peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Two Dose Levels of Taliglucerase Alfa in Pediatric Subjects With Gaucher Disease
Status: COMPLETED
Conditions: Gaucher Disease
Interventions: DRUG: Taliglucerase alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Higher Dose Weekly Topotecan In The Treatment Of Patients With Extensive Stage Small-Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Cancer|Carcinoma, Small Cell
Interventions: DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Insulin Pump Therapy in Adolescents With Newly Diagnosed Type 1 Diabetes (T1D)
Status: COMPLETED
Conditions: Diabetes Mellitus, Insulin-Dependent
Interventions: DEVICE: Insulin pump therapy|DRUG: Multiple daily injections using insulin glargine + rapid acting analog
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: LY3954068|DRUG: Placebo|DRUG: Flortaucipir F18
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy Of Doxophylline As A Sparing Treatment For Inhaled Corticosteroids In Mexican Children With Asthma
Status: UNKNOWN
Conditions: Asthma Chronic|Asthma in Children
Interventions: DRUG: Doxophylline|DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ZD9331 With or Without Topotecan in Treating Patients With Refractory or Recurrent Epithelial Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: plevitrexed|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety in Pacemaker and Defibrillator Implantation Via Cephalic Versus Axillary Vein Access (CEPHAX)
Status: UNKNOWN
Conditions: Pacemakers|Defibrillators|Complication|Pacemaker Electrode Lead Fracture
Interventions: DEVICE: Pacemaker implant|DEVICE: Defibrillator implant|PROCEDURE: AXILLARY VEIN ACCESS|PROCEDURE: CEPHALIC VEIN ACCESS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Development of a Motivational Intervention to Improve Treatment Adherence in MS
Status: COMPLETED
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: BEHAVIORAL: Motivational Interviewing-Cognitive Behavioral Therapy|BEHAVIORAL: Brief Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of One-time Versus Three-times of Umbilical Cord Milking on Neonatal Hemoglobin in Late Preterm
Status: COMPLETED
Conditions: Umbilical Cord Milking
Interventions: OTHER: one-time umbilical cord milking|OTHER: three-times umbilical cord milking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study in Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Tadalafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Dapagliflozin in Diabetes Associated Peripheral Neuropathy
Status: UNKNOWN
Conditions: Diabetic Peripheral Neuropathy
Interventions: DRUG: Dapagliflozin 10 milligram|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Internet-Based Intervention for Occupational Stress Among Medical Professionals
Status: COMPLETED
Conditions: Stress, Psychological, Occupational|Burnout, Professional
Interventions: BEHAVIORAL: Personal resources' enhancement: self-efficacy and perceived social support|BEHAVIORAL: Personal resources' enhancement: perceived social support and self-efficacy|BEHAVIORAL: Personal resources' enhancement: self-efficacy|BEHAVIORAL: Personal resources' enhancement: perceived social support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Control of Helicobacter Pylori Infection by Dietary Supplementation With Lactobacillus Reuteri
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection|Dyspepsia
Interventions: DIETARY_SUPPLEMENT: Lactobacillus reuteri|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Rehabilitation Protocols in Parkinson's Disease With Postural Instability and Gait Disorders
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Gait and balance training with dual-task + action observation and motor imagery (six weeks)|BEHAVIORAL: Gait and balance training with dual-task (six weeks)|BEHAVIORAL: Gait and balance training with dual-task + action observation and motor imagery (twelve weeks: 6 + 6)|BEHAVIORAL: Gait and balance training with dual-task (twelve weeks: 6 +6)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Head- to Head Comparison of [68Ga]Ga-PSMA-11 With [18F]PSMA-1007 PET/CT in Staging Prostate Cancer Using Histopathology and Immunohistochemical Analysis as Reference-Standard
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: F18-PSMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of a 4-week Acu-Transcutaneous Electrical Nerve Stimulation (Acu-TENS) Program on Subjects With Stable Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DEVICE: Acu-TENS (Transcutaneous electrical nerve stimulation)|DEVICE: Acu-TENS (Transcutaneous electrical nerve stimulation)|DEVICE: Acu-TENS (Transcutaneous electrical nerve stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cantharidin Application in Molluscum Patients-1
Status: COMPLETED
Conditions: Molluscum Contagiosum
Interventions: COMBINATION_PRODUCT: VP-102 - Cantharidin, Topical Film Forming Solution|COMBINATION_PRODUCT: Placebo -Topical Film Forming Solution without VP-102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of the Symptomatic Sacral Perineurial Cysts
Status: UNKNOWN
Conditions: Pain
Interventions: PROCEDURE: sacral canal cyst microscopic tamponade|DRUG: gabapentin + tramadol|DEVICE: resting state functional magnetic resonance imaging (rfMRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Telerehabilitation of Working Memory in Children With Periventricular Leukomalacia and Bilateral Cerebral Palsy
Status: COMPLETED
Conditions: Periventricular Leukomalacia
Interventions: OTHER: Cluster B CogMed: an home-based and computer-based solution to improve working memory deficit|OTHER: Cluster A No training. Delay start of CogMed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DWP450 Treatment in Subjects With Benign Masseteric Hypertrophy
Status: UNKNOWN
Conditions: Benign Masseteric Hypertrophy
Interventions: DRUG: Botulinum toxin type A|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurally Adjusted Ventilatory Assist in Adults at Risk of Delayed Weaning From Mechanical Ventilation
Status: COMPLETED
Conditions: Adults With Cardiopulmonary Disease at Risk of Prolonged Weaning From Mechanical Ventilation
Interventions: OTHER: NAVA Technology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of MK-0616 in Participants With Moderate Renal Impairment (MK-0616-007)
Status: COMPLETED
Conditions: Moderate Renal Impairment
Interventions: DRUG: MK-0616
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiosensitizing and Radioprotectve Effects of Curcumin in Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Radiation Therapy
Interventions: DIETARY_SUPPLEMENT: Curcumin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does a Phone-based Meditation Application Improve Mental Wellness in Emergency Medicine Personnel?
Status: UNKNOWN
Conditions: Burnout, Professional|Depression|Anxiety|Stress
Interventions: BEHAVIORAL: Cleveland Clinic Stress Free Now Meditations For Healers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of CHOP + Campath for T-Cell, Null Cell, or Natural Killer (NK)-Cell Lymphoma
Status: COMPLETED
Conditions: T-Cell Lymphoma|Lymphoma, Non-Hodgkin's
Interventions: DRUG: CHOP and alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blame Rebalance fMRI Feedback Proof-of-concept
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: GUILT-INCREASE-CORRELATION|DEVICE: GUILT-STABILIZE-CORRELATION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating Long-term Safety of Efgartigimod Administered Intravenously and Efgartigimod PH20 Administered Subcutaneously in Children With Generalized Myasthenia Gravis
Status: ENROLLING_BY_INVITATION
Conditions: Generalized Myasthenia Gravis
Interventions: BIOLOGICAL: Efgartigimod IV or Efgartigimod PH20 SC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Dexmedetomidine on Sleep Quality
Status: COMPLETED
Conditions: Elderly|Surgery|Analgesia|Dexmedetomidine|Complication,Postoperative|Sleep Quality
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing Methods for Balloon Catheter Inserting: View Guided (Speculum) Versus Manual Guided at Cervical Examination
Status: RECRUITING
Conditions: Cervical Ripening
Interventions: PROCEDURE: balloon catheter insertion approach for labor induction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Dasatinib and All-Trans Retinoic Acid for Relapsed/Refractory and/or Elderly Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: dasatinib (SPRYCEL)|DRUG: all trans retinoic acid (VESANOID)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Bathing Additives in the Treatment of Pediatric Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis|Eczema
Interventions: PROCEDURE: Water|PROCEDURE: Bleach|PROCEDURE: Acetic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Osteopathic Manipulative Treatment on Pursuit Eye Movements in Healthy Human Adults
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Osteopathic manipulative treatment|OTHER: Sham Osteopathic manipulative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Head Motion in Pediatric Patients Endotracheally Intubated With Video Laryngoscopy Versus Direct Laryngoscopy
Status: COMPLETED
Conditions: Intubation; Difficult|Cervical Spine Injury
Interventions: PROCEDURE: Video Laryngoscopy|PROCEDURE: Direct Laryngoscopy|DEVICE: Storz C-Mac® laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Translational Study of Bevacizumab in Participants With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: Oxaliplatin|DRUG: Capecitabine|DRUG: Bevacizumab|DRUG: Leucovorin|DRUG: 5-Fluouracil|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Based Blood Pressure Reduction: Stage 2a RCT
Status: COMPLETED
Conditions: Hypertension|Prehypertension
Interventions: BEHAVIORAL: MB-BP Intervention|OTHER: Enhanced Usual Care Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ologen(Oculusgen)-Glaucoma and Pterygium Historical Control Study in China Shanghai Sixth People's Hospital
Status: UNKNOWN
Conditions: Glaucomas|Pterygium
Interventions: DEVICE: ologen™ Collagen matrix implantation in glaucoma filtering surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study Evaluating the Effect of Rifampin on PK and Safety of PF 04965842.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-04965842|OTHER: rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Thoraflex in the Treatment of Aneurysm or Penetrating Ulcer of the Descending Thoracic Aorta
Status: WITHDRAWN
Conditions: Aortic Aneurysm, Thoracic|Penetrating Aortic Ulcers (PAUs)
Interventions: DEVICE: Thoracic Endovascular Stent Graft System (ThoraflexTM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glutamine Plus L. Reuteri Prevents TKI Therapy-diarrhea in Patients With NSCLC
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer With EGFR Mutation
Interventions: COMBINATION_PRODUCT: Glutamine plus L. reuteri
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IUL Study A Randomized Sham - Controlled Clinical Study
Status: RECRUITING
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: Intraurethral laser therapy|DEVICE: Intraurethral SHAM laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: CTCs in Breast Cancer After Neoadjuvant Treatment and Surgery: a Multicenter, Prospective Clinical Trial
Status: RECRUITING
Conditions: Breast Cancer|Circulating Tumor Cell
Interventions: DEVICE: GILUPI CellCollector®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: HORNBILL: A Study to Test Different Doses of BI 764524 in Patients Who Have Had Laser Treatment for a Type of Diabetic Eye Disease Called Diabetic Retinopathy With Diabetic Macular Ischemia
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DRUG: BI 764524|DRUG: Sham control of BI 764524
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Haplo-identical HSCT Versus Chemotherapy for Adult Acute Lymphoblastic Leukemia Patients
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: PROCEDURE: Haplo-identical HSCT|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxybutynin Chloride in Managing Hot Flashes
Status: COMPLETED
Conditions: Breast Carcinoma|Ductal Breast Carcinoma In Situ|Hot Flashes|Lobular Breast Carcinoma In Situ|No Evidence of Disease
Interventions: DRUG: Oxybutynin Chloride|OTHER: Placebo|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: First-in-Human Single and Multiple Dose of EB8018
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Single Ascending Doses of EB8018|DRUG: Single Ascending Doses of placebo|DRUG: Multiple Ascending Doses of EB8018|DRUG: Multiple Ascending Doses of placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brief CBT for Anxiety and Advanced Cancer
Status: COMPLETED
Conditions: Anxiety|Depression|Unspecified Adult Solid Tumor, Protocol Specific|Cancer|Cognitive Behavioral Therapy
Interventions: BEHAVIORAL: Brief Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Combination Therapy With Irinotecan, S-1, and Bevacizumab (IRIS/Bev) in Patients With Unresectable or Recurrent Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: S-1, Irinotecan, Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Effect of Lactulose on Hard Stools in Patients With Hemorrhoids or Anal Fissures
Status: TERMINATED
Conditions: Hemorrhoids|Anal Fissures
Interventions: DRUG: Lactulose|DRUG: Plantago ovata
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medication Adherence in Human Immunodeficiency Virus (HIV)
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: BEHAVIORAL: Staff-delivered intervention sessions|OTHER: Demographic Questionnaire|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Study of Heart Polypill Safety and Efficacy in Primary Prevention of Cardiovascular Disease
Status: COMPLETED
Conditions: Cardiovascular Disease|Hypertension|Hyperlipidemia|Heart Disease
Interventions: DRUG: Polypill|DRUG: Placebo drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improving Substance Use and Clinical Outcomes in Heavy Cannabis Users With Quetiapine
Status: COMPLETED
Conditions: Cannabis Dependence
Interventions: BEHAVIORAL: Behavioral Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: G7 Acetabular System vs. Exceed ABT Acetabular System in THA
Status: COMPLETED
Conditions: Osteoarthritis Arthritis|Rheumatoid Arthritis
Interventions: DEVICE: G7|DEVICE: Exceed ABT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: "Interactive Metronome Technology for Blast-Related Traumatic Brain Injury"
Status: COMPLETED
Conditions: Traumatic Brain Injury|Post-Concussion Syndrome
Interventions: BEHAVIORAL: Interactive metronome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Tomography / Magnetic Resonance Imaging (PET/MRI) Guided Biopsy in Men With Elevated PSA
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: [68Ga]PSMA-11|DRUG: [18F]PSMA-1007
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Assessment of the Safety of a Combination of Curcumin, Omega-3, and Vitamin D Supplements in ACPA+ Individuals
Status: NOT_YET_RECRUITING
Conditions: Healthy Participants
Interventions: COMBINATION_PRODUCT: curcumin, omega-3, and vitamin D (COD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Metformin in Head and Neck Squamous Cell Carcinoma: Effect on Tissue Oxygenation
Status: COMPLETED
Conditions: Head and Neck Cancer|Oral Cavity Squamous Cell Carcinoma
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: NeuroPathways Intervention for Brain Tumor Patients
Status: RECRUITING
Conditions: Malignant Brain Tumor|Glioma|Coping Skills
Interventions: BEHAVIORAL: Information and Support Intervention|OTHER: Usual supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Camrelizumab Combined With Radiotherapy for Adjuvant Treatment of Esophageal Squamous Cell Carcinoma After Surgery
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinomas
Interventions: DRUG: Camrelizumab|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-Operator Versus Dual-Operator Double-balloon Endoscopy in Patients With Small-Bowel Disorders
Status: UNKNOWN
Conditions: Small-Bowel Disorders
Interventions: PROCEDURE: Single-operator double-balloon endoscopy|PROCEDURE: dual-operator double-balloon endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Oshadi D and Oshadi R in Combination With Docetaxel, as 2nd Line Therapy for Metastatic Non Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Oshadi D and Oshadi R|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of CAD-EYE/SCALE-EYE for Detection, Classification, and Measurement of Colorectal Polyps: a Prospective Study
Status: COMPLETED
Conditions: Colorectal Polyp|Colorectal Adenoma
Interventions: DIAGNOSTIC_TEST: Detection and classification and size measurement of polyp by Artificial Intelligence (Cad eye) and the Scale Eye
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC