pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Investigate the Safety and Efficacy of TEG002 in Relapsed/Refractory Multiple Myeloma Patients
Status: UNKNOWN
Conditions: Multiple Myeloma, Refractory|Multiple Myeloma in Relapse|Multiple Myeloma
Interventions: BIOLOGICAL: TEG002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Two Different Treatment Modalities in Patients With Spinal Muscular Atrophy
Status: ACTIVE_NOT_RECRUITING
Conditions: Muscular Atrophy, Spinal
Interventions: OTHER: Pulmonary Rehabilitation|OTHER: Trunk Control Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Chemoradiotherapy With or Without Paclitaxel in Squamous-cell Anal Carcinoma Patients
Status: UNKNOWN
Conditions: Anus Neoplasms|Carcinoma, Squamous Cell|Anus Diseases|Neoplasms|Neoplasms, Squamous Cell|Carcinoma
Interventions: DRUG: Paclitaxel|DRUG: Capecitabine|DRUG: Capecitabine|DRUG: Mitomycins|DRUG: Mitomycins|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Abatacept in Patients With Active Crohn's Disease
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DRUG: abatacept|DRUG: placebo|DRUG: abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Imaging to Predict the Deep Surgical Margin in Gingivobuccal Complex Tumors
Status: UNKNOWN
Conditions: Buccal Mucosa Cancer|Gingival Cancer
Interventions: PROCEDURE: Clinical Evaluation|DIAGNOSTIC_TEST: Radiological Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gemcitabine and ON 01910.Na in Previously Untreated Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: ON 01910.Na|DRUG: Gemcitabine|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Left vs. Right Non-Inferiority Trial
Status: RECRUITING
Conditions: Depression|Major Depressive Disorder|Major Depressive Episode
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation|DEVICE: Intermittent Theta Burst Stimulation (iTBS)|DEVICE: Low Frequency Right (LFR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Combined With Sufentanil for Preventing Catheter-related Bladder Discomfort
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: lidocaine and sufentanil|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Multicomponent Lipid Emulsion in Preterm Infants Requiring Parenteral Nutrition
Status: COMPLETED
Conditions: Cholestasis
Interventions: DRUG: multicomponent lipid emulsion|DRUG: pure soybean oil lipid emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: What is the Maximum Amount of Carbohydrates That is Still Able to Induce Ketosis and Suppress Appetite?
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Low energy diet 70 gram carbohydrates|OTHER: Low energy diet 100 gram carbohydrates|OTHER: Low energy diet 130 gram carbohydrates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Eustachian Tube Dilation With an Endovascular Balloon
Status: COMPLETED
Conditions: Eustachian Tube Dysfunction|Eustachian Tube Dysfunction of Both Ears
Interventions: DEVICE: Eustachian tube dilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Tolerability of ASA404 Administered in Combination With Docetaxel in Japanese Patients With Solid Tumors
Status: COMPLETED
Conditions: Advanced or Recurrent Solid Tumors
Interventions: DRUG: vadimezan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Pressure and Weight Trajectory on a Dual Antihypertensive Combination Plus Sibutramine Versus Placebo in Obese Hypertensives
Status: COMPLETED
Conditions: Obesity|Hypertension
Interventions: DRUG: sibutramine|DRUG: sibutramine|DRUG: verapamil/trandolapril|DRUG: metoprolol/HCT|DRUG: felodipine/ramipril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 68Ga-NODAGA-exendin-4 PET/CT for Diagnostic Imaging in AHH
Status: COMPLETED
Conditions: Insulinoma
Interventions: RADIATION: 68Ga-NODAGA-exendin 4 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Laparoscopy-assisted and Open Distal Gastrectomy for Gastric Cancer in the Elderly Patients
Status: UNKNOWN
Conditions: Complications
Interventions: PROCEDURE: Laparoscopic gastrectomy|PROCEDURE: Open gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ramucirumab (LY3009806) or Merestinib (LY2801653) in Advanced or Metastatic Biliary Tract Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Biliary Tract Cancer|Metastatic Cancer|Advanced Cancer
Interventions: DRUG: Ramucirumab|DRUG: Merestinib|DRUG: Cisplatin|DRUG: Gemcitabine|DRUG: Placebo Oral|DRUG: Placebo IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Miglustat in Niemann-Pick Type C Disease
Status: COMPLETED
Conditions: Niemann-Pick Type C Disease
Interventions: DRUG: miglustat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MICI-CMV:Valganciclovir in Recurrent Bouts of Cryptogenic Inflammatory Bowel Diseases With an Infection by Cytomegalovirus
Status: TERMINATED
Conditions: Cytomegalovirus Infections|Inflammatory Bowel Diseases
Interventions: DRUG: Valganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Intra- and Inter-evaluator Reproducibility of Upper Limb Strength Measures in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Enhancing Recovery of Arm Movement in Stroke Patients
Status: COMPLETED
Conditions: Stroke|Arm|Paresis
Interventions: DEVICE: tDCS|DEVICE: sham tDCS|BEHAVIORAL: personalized practice|BEHAVIORAL: non-personalized practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized, Placebo-Controlled Pilot Study to Characterize the Intestinal Microbiome and to Evaluate the Safety and Fecal Microbiome Changes Following Administration of Lyophilized PRIM-DJ2727 or Placebo Given Orally in Subjects With Nonalcoholic Fatty Liver Disease
Status: WITHDRAWN
Conditions: Nonalcoholic Fatty Liver Disease (NAFLD) With History of Diabetes Melitus
Interventions: DRUG: PRIM-DJ2727|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microbiological Spectrum of the Intraperitoneal Surface After Elective Right-sided Colon Cancer
Status: UNKNOWN
Conditions: Peritoneal Contamination After Ileocolonic Anastomosis|Wound Infection|Intra-abdominal Abscess
Interventions: PROCEDURE: Stapled anastomosis|PROCEDURE: Handsewn anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ENterogermina® (Bacillus Clausii) In the manaGeMent of diarrheA in Children
Status: COMPLETED
Conditions: Gastroenteritis
Interventions: DRUG: Bacillus Clausii|OTHER: Oral rehydration therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening Brain MRI in High School Football: Does the Guardian Cap Reduce the Risk of Traumatic Brain Injury
Status: TERMINATED
Conditions: Brain Concussion|Brain Injuries|Diffuse Axonal Injury|Athletic Injuries|Injury, Brain, Traumatic
Interventions: DEVICE: Guardian Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Different Concentrations of Epidural Bupivacaine for the Effects on Vasodilatation and Sensory Block
Status: COMPLETED
Conditions: Intraoperative Complications
Interventions: DRUG: Epidural bupivacaine (dose/concentration/volume ranging)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effect of Nebulized Milrinone on Right Ventricular Hemodynamics in Adult Cardiac Surgery
Status: UNKNOWN
Conditions: Anesthesia
Interventions: DRUG: Milrinone|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AZD9150 Plus Durvalumab Alone or in Combination With Chemotherapy in Patients With Advanced, Solid Tumours and in Patients With Non-Small-Cell Lung Cancer
Status: COMPLETED
Conditions: Advanced Solid Tumours
Interventions: DRUG: AZD9150|DRUG: Durvalumab|DRUG: Cisplatin|DRUG: 5-Flourouracil|DRUG: Carboplatin|DRUG: Gemcitabine|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Non-opioid Balanced General Anesthesia in Cardiac Surgery With Extracorporeal Circulation: a Randomized, Controlled, Multicenter Superiority Trial
Status: COMPLETED
Conditions: Opioid-free Anesthesia|Cardiac Surgery
Interventions: DRUG: Balanced general anesthesia without morphine|DRUG: Standard general anesthesia balanced with morphine|OTHER: Data collection|OTHER: Assessment of pain|OTHER: Recovery quality score
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Supine or Prone Position After Caesarean Birth
Status: COMPLETED
Conditions: Respiratory Distress|Transient Tachypnea of the Newborn|Delayed Transition of the Newborn|Persistent Pulmonary Hypertension
Interventions: PROCEDURE: prone positioning|PROCEDURE: Supine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of Soft Tissue Augmentation Using CTG and PRF Around Immediately Placed Dental Implants Versus Immediate Implant Alone in Esthetic Zone .
Status: COMPLETED
Conditions: Soft Tissue Augmentation
Interventions: DEVICE: immediate implant|BIOLOGICAL: connective tissue graft|BIOLOGICAL: platelet rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy of Digital Cognitive Behavioral Therapy With Wearable Device for Insomnia
Status: COMPLETED
Conditions: Insomnia
Interventions: DEVICE: WELT-IP with wearable devices (Apple/galaxy watch. Oura ring)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Neuromodulation With Connectivity-Guided iTBS for Cognitive Impairment in MS
Status: RECRUITING
Conditions: Multiple Sclerosis|Cognitive Impairment
Interventions: OTHER: Intermittent theta burst stimulation (iTBS)|OTHER: Sham Intermittent theta burst stimulation (iTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Gait Adaptation and Biofeedback for Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: DEVICE: Biomotum Spark: Robotic ankle resistance|DEVICE: Audiovisual Biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Active tDCS Versus Sham tDCS for Upper Limb Recovery in Incomplete Tetraplegic Patients
Status: RECRUITING
Conditions: Spinal Cord Injury Cervical
Interventions: PROCEDURE: Active tDCS|PROCEDURE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sarecycline in Patients With Acute Ischemic Stroke After Reperfusion Therapy
Status: RECRUITING
Conditions: Ischemic Stroke, Acute
Interventions: DRUG: Sarecycline Tablet|DRUG: Placebo tablets of Sarecycline tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Transversus Abdominis Plane Block and Ilioinguinal / Iliohypogastric Nerve Block
Status: UNKNOWN
Conditions: Intra-operative Anesthesia
Interventions: DRUG: ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose-Finding Pilot Study of ACTH in Patients With Idiopathic Membranous Nephropathy
Status: COMPLETED
Conditions: Idiopathic Membranous Nephropathy
Interventions: DRUG: ACTH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Severe Hypertension During Pre-Eclampsia: A Preliminary Equivalence Study Between Urapidil and Nicardipine
Status: UNKNOWN
Conditions: Hypertension During Pre-Eclampsia
Interventions: DRUG: URAPIDIL (EUPRESSYL*)|DRUG: NICARDIPINE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lactoferrin Efficacy Versus Ferrous Sulfate in Treatment of Patients With Iron Deficiency Anemia
Status: COMPLETED
Conditions: Iron Deficiency Anemia Treatment
Interventions: DRUG: Lactoferrin Bovine|DRUG: Ferrous Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Study to Evaluate Safety, Tolerability, PK, and Efficacy of SER-155 in Adults Undergoing HSCT
Status: ACTIVE_NOT_RECRUITING
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Vancomycin Pre-Treatment|DRUG: Vancomycin Placebo|DRUG: SER-155|DRUG: SER-155 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ramelteon in the Prevention of Post-operative Delirium
Status: COMPLETED
Conditions: Delirium|Delirium, Dementia, Amnestic, Cognitive Disorders|Delayed Emergence From Anesthesia|Cognitive Disorders
Interventions: DRUG: Ramelteon|DRUG: Microcrystalline Cellulose|DRUG: Riboflavin 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: AZD2281 and Irinotecan in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: irinotecan hydrochloride|DRUG: olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sirolimus Treatment Of Patients With SLE
Status: NOT_YET_RECRUITING
Conditions: Lupus Erythematosus, Systemic
Interventions: DRUG: Sirolimus|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Parallel Arm Phase 1b/2a Study of DKN-01 as Monotherapy or in Combination With Docetaxel for the Treatment of Advanced Prostate Cancer With Elevated DKK1
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: DKN-01|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genomic Analysis of Families With a History of Discordant Cancers
Status: NOT_YET_RECRUITING
Conditions: Discordant Cancers
Interventions: GENETIC: WES via Illumina NextSeq 550 sequencing system|DIAGNOSTIC_TEST: Blood Draw|DIAGNOSTIC_TEST: Skin biopsy|DIAGNOSTIC_TEST: Saliva Sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: At-home Bleaching Using Clear Aligners
Status: RECRUITING
Conditions: Tooth Discoloration|Tooth Sensitivity|Gingivitis|Satisfaction, Patient
Interventions: OTHER: Whitening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised Clinical Trial in a Population of Health Care Workers With Hand Eczema
Status: UNKNOWN
Conditions: Eczema|Dermatitis|Skin Disease
Interventions: BEHAVIORAL: A randomised clinical trial of the effect of classification and individual counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Development of Clinical Method to Triclosan Retention in Plaque Following Brushing
Status: COMPLETED
Conditions: Dental Plaque
Interventions: DRUG: Fluoride|DRUG: Fluoride and triclosan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Protein Intake Using 2 Types of Nutritional Collection in Chronic Kidney Disease.
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Kidney Disease (Stages 4 and 5)
Interventions: OTHER: 3-day dietary record|OTHER: Food Frequency Questionnaire (FFQ)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety/Tolerability, Pharmacokinetics/Pharmacodynamics (PK/PD) of LCZ696 in Patients With Stable Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: LCZ696
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acthar SLE (Systemic Lupus Erythematosus)
Status: WITHDRAWN
Conditions: Systemic Lupus Erythematosus (SLE)|Repository Corticotropin Injection
Interventions: DRUG: Acthar low dose (40 U)|DRUG: Acthar high dose (80 U)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: temozolomide|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Cognitive-motor Dual Task Training in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Cognitive Impairment|Motor Disorders
Interventions: OTHER: Dynamic Postural Stability Training|OTHER: Cognitive-Motor Training|OTHER: Conventional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Wrong-Patient Computerized Physician Order Entry (CPOE) Errors
Status: COMPLETED
Conditions: Wrong Patient Computerized Physician Order Entry Errors
Interventions: OTHER: Passive Intervention|OTHER: Active Intervention|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety of Inhaled Human Insulin in Subjects With Diabetes Mellitus and Chronic Obstructive Pulmonary Disease (COPD)
Status: TERMINATED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Chronic Obstructive Pulmonary Disease
Interventions: DRUG: inhaled human insulin|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-up of People at Risk of Monkeypox Infection: a Prospective Cohort Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Monkey Pox|Monkey Diseases
Interventions: BIOLOGICAL: Vaccination with MVA vaccine ( IMVANEX® and JYNNEOS®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of BN301, an Anti-CD74 Antibody Drug Conjugate, in Patients With Advanced B-Cell Malignancies
Status: TERMINATED
Conditions: B-cell Lymphoma|Non Hodgkin Lymphoma|Diffuse Large B Cell Lymphoma|Follicular Lymphoma|Mantle Cell Lymphoma
Interventions: DRUG: BN301
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Efficacy and Safety Assessment of T2345 Compared With Active Comparator in Newly Diagnosed Patients With Open-angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma
Interventions: DRUG: T2345|DRUG: Prostaglandin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label, Multi-centre, Non-interventional Post-marketing Surveillance to Monitor the Safety and/or Efficacy of AVANDAMET Between June 2004 and January 2010
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Administration of rosiglitazone/metformin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease
Status: UNKNOWN
Conditions: Stable Angina|Myocardial Infarction|Coronary Heart Disease|Heart Failure|Stroke|Death, Sudden, Cardiac|Peripheral Arterial Disease|Atrial Fibrillation|Bleeding
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Supportive Care During Childbirth and Well-being
Status: COMPLETED
Conditions: Psychological Well-being|Childbirth|Care Pattern, Maternal
Interventions: OTHER: Continouse supportive care|OTHER: routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of Utility of Exhaled Nitric Oxide Measurement for Treatment Monitoring in Children With Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: DEVICE: exhaled nitric oxide measurement|PROCEDURE: bronchial hyperresponsiveness with methacholine (PC20M)|PROCEDURE: symptom score diary (according to 2007 GINA guidelines)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Obtaining and Storing Human Blood, Urine, and Fecal Samples for Spirochete-Related Epidemiological Research
Status: COMPLETED
Conditions: The Samples Will be Studied in Order to Attempt to Better Understand the Occurrence of Blood, Feces and Urine Borne Spirochaetes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Simple ECG Monitoring Trial (Comparison of a Novel Recording System With a Standard Holter Monitor)
Status: COMPLETED
Conditions: Syncope|Pre-syncope|Atrial Fibrillation|Supraventricular Tachycardia
Interventions: DEVICE: Standard Holter/Investigational patch
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Talazoparib For Neoadjuvant Treatment Of Germline BRCA1/2 Mutation Patients With Early Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer
Status: TERMINATED
Conditions: Early Breast Cancer
Interventions: DRUG: TALAZOPARIB
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of [123I] MNI-308 and SPECT as a Marker of Beta-amyloid Protein Deposition in AD Subjects Compared to HC
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DRUG: [123I] MNI-308
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study on Efficacy and Safety of Chondroitin Sulfate + Glucosamine Hydrochloride Versus Celecoxib in Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Chondroitin/Glucosamine (Droglican)|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dialectical Behavior Therapy for Justice-Involved Veterans
Status: RECRUITING
Conditions: Criminal Behavior|Criminal Recidivism|Psychosocial Functioning
Interventions: BEHAVIORAL: Dialectical Behavior Therapy for Justice-Involved Veterans|BEHAVIORAL: Supportive Group Psychotherapy for Justice-Involved Veterans
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Randomised Controlled Trial of ToQuit Intervention in India
Status: COMPLETED
Conditions: Tobacco Use
Interventions: BEHAVIORAL: ToQuit, a technology delivered tobacco cessation intervention|BEHAVIORAL: Tobacco quitting helplines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Nutrition Caffeine Intake in Healthy Adults.
Status: COMPLETED
Conditions: CYP1A2 Polymorphism
Interventions: BEHAVIORAL: Intervention group with genotype information|BEHAVIORAL: Control group without genotype information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reducing Sedentary Behaviour in Office Workers With a HAPA mHealth Intervention and a Just In-Time Adaptive Intervention
Status: UNKNOWN
Conditions: Sedentary Behaviour|Health Behaviour Change
Interventions: BEHAVIORAL: HAPA behavioural counselling + SMS text message boosters|DEVICE: JITAI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Hot Flashes and Night Sweats in Postmenopausal Women Receiving Combination Raloxifene and Oral Estrogen
Status: COMPLETED
Conditions: Vasomotor Symptoms|Endometrial Safety
Interventions: DRUG: Raloxifene|DRUG: medroxyprogesterone acetate|DRUG: estrogen|DRUG: 17 beta estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Timing to Restart Direct Oral Anticoagulants After Traumatic Intracranial Haemorrhage
Status: NOT_YET_RECRUITING
Conditions: Traumatic Intracranial Haemorrhage
Interventions: DRUG: Direct-Acting Oral Anticoagulants (used as per local standard practice)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implication of Cognitive Reserve in Non-pharmacological Intervention Outcomes
Status: RECRUITING
Conditions: Aging|Mild Cognitive Impairment|Dementia With Lewy Bodies
Interventions: DEVICE: transcranial alternating current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety and Efficacy of IPX203 in Parkinson's Disease Participants With Motor Fluctuations
Status: COMPLETED
Conditions: Parkinson's Disease (Disorder)
Interventions: DRUG: IR CD-LD|DRUG: IPX203 ER CD-LD|OTHER: Placebo Matching IPX203|OTHER: Placebo Matching IR CD-LD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy and Safety of Fluticasone Furoate/Vilanterol Trifenatate in the Treatment of Asthma in Adolescent and Adult Subjects of Asian Ancestry
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: GW685698/GW642444|DRUG: CCI18781
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Compare Safety and Pharmacokinetic Characteristics of CKD-337
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: Lipitor + Lipidil supra|DRUG: CKD-337
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Performance of 18F-FDG-PET and Diffusion-weighted MRI in the Assessment of Stage IB to IIB2 Cervical Squamous-cell Carcinoma Response to Concomitant Radiochemotherapy and Brachytherapy
Status: COMPLETED
Conditions: Cancer of the Uterine Cervix
Interventions: DEVICE: 18F-FDG-PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Optimizing Management and Medication of Febrile Children in Out-of-hours Primary Care: CHILI Cluster RCT
Status: COMPLETED
Conditions: Antibiotic Prescriptions|Infection
Interventions: BEHAVIORAL: GP-parent information-exchange tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Rate of Falls in Older People by Means of Vestibular Rehabilitation: Preliminary Study
Status: COMPLETED
Conditions: Dizziness Chronic|Fall|Elderly
Interventions: DEVICE: Vestibular rehabil.: CDP|DEVICE: Vestibular rehabil.: optokinetic stimuli|OTHER: Vestibular rehabil.: home exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Measuring Ambulation, Motor, and Behavioral Outcomes With Post-Stroke Fluoxetine in Tanzania
Status: COMPLETED
Conditions: Acute Stroke|Stroke, Ischemic
Interventions: DRUG: Fluoxetine 20 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor Umbilical Cord Blood Transplantation in Treating Patients With Leukemia, Lymphoma, or Nonmalignant Hematologic Disorders
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Myelodysplastic Syndromes|Myelodysplastic-Myeloproliferative Diseases
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: filgrastim|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: melphalan|DRUG: methylprednisolone|PROCEDURE: umbilical cord blood transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Thalidomide on Symptom Clusters
Status: COMPLETED
Conditions: Advanced Cancers
Interventions: DRUG: Thalidomide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Collagenase Option for Reduction of Dupuytren's Contracture in Japan
Status: COMPLETED
Conditions: Dupuytren's Contracture
Interventions: DRUG: Collagenase Clostridium Histolyticum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability Study of a Modified-Release Formulation of PF-06865571 in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: PF-06865571 400 mg Immediate Release (IR) in Fed State|DRUG: PF-06865571 50 mg Modified Release (MR) in Fed State|DRUG: PF-06865571 400 mg MR in Fed State|DRUG: PF-06865571 400 mg MR in Fasted State
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Retraining and Control Therapy (ReACT) R33 Phase
Status: RECRUITING
Conditions: Convulsion, Non-Epileptic
Interventions: BEHAVIORAL: ReACT|BEHAVIORAL: Supportive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Hydrolyzed Chicken Collagen Type II in Alleviating Joint Discomfort
Status: COMPLETED
Conditions: Joint Discomfort
Interventions: DIETARY_SUPPLEMENT: AVC-H2|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Duration of Skin Numbing Effect Created by the S-Caine™ Peel
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: S-Caine™ Peel (lidocaine and tetracaine cream 7%/7%)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OPTIONS: A Patient-Centered HIV Prevention Decision Aid for PrEP Uptake for Women With Substance Use in Treatment Settings
Status: COMPLETED
Conditions: HIV Infections|Substance Abuse
Interventions: BEHAVIORAL: Decision aid|BEHAVIORAL: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability and Pharmacodynamic Activity of Sotagliflozin in Hemodynamically Stable Participants With Worsening Heart Failure
Status: TERMINATED
Conditions: Cardiac Failure Aggravated
Interventions: DRUG: Sotagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tirzepatide in Participants With Type 2 Diabetes Mellitus (T2DM)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Tirzepatide|DRUG: Semaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study on the Immune Response and Safety of a Vaccine Against Herpes Zoster in Adults Aged 50 Years and Older in India
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: HZ/su|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Intravenous or Subcutaneous Methoxy Polyethylene Glycol-Epoetin Beta (RO0503821, Mircera) in Chronic Kidney Disease Patients With Renal Anemia
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Methoxy Polyethylene Glycol-Epoetin Beta|DRUG: Epoetin alfa|DRUG: Epoetin beta|DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REAL HEALTH-Diabetes: Reach Ahead for Lifestyle and Health-Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Obesity
Interventions: BEHAVIORAL: In Person Group (IP)|BEHAVIORAL: Telephone Conference Call Group (TCC)|BEHAVIORAL: Medical Nutrition Therapy (MNT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD7594 Inhaled Formulation in Healthy Japanese Men
Status: COMPLETED
Conditions: Asthma|Chronic Obstructive Pulmonary Disease COPD
Interventions: DRUG: AZD7594 inhalation powder (200 μg)|DRUG: AZD7594 inhalation powder (400 μg)|DRUG: AZD7594 pressurized inhalation suspension (200 μg)|DRUG: AZD7594 placebo inhalation powder|DRUG: AZD7594 placebo pressurized inhalation suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of Thioctacid Oral Tablets 600mg to Treat Chinese Diabetic Patients With Distal Symmetric Polyneuropathy
Status: UNKNOWN
Conditions: Diabetics
Interventions: DRUG: lipoic acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tirzepatide in Participants With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Hypoglycemia
Interventions: DRUG: Tirzepatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Retroflexion in the Entire Colon for the Detection of Colon-related Diseases
Status: UNKNOWN
Conditions: Colon Cancer Screening|Colon Polyps
Interventions: DIAGNOSTIC_TEST: Retroflexion in the total colon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Study of Intracameral Adrenaline for Pupil Dilation Without Topical Mydriatics in Refractive Cataract Surgery
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: adrenalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Technology-Based Well-Being Process Program (WEBEPROP) for Children and Adolescents in Palliative Care
Status: NOT_YET_RECRUITING
Conditions: Childhood Cancer
Interventions: OTHER: Well-Being Process Program (WEBEPROP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Assess TOPO2A as a Biomarker for Sensitivity to Doxorubicin/Doxil in Soft Tissue Sarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Doxil|DRUG: Doxorubicin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tonation Breathing Technique Method to Ease Aromatase Inhibitor-induced Joint and/or Muscle Pain
Status: COMPLETED
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8
Interventions: OTHER: Questionnaire Administration|BEHAVIORAL: Tonation Breathing Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Algometer and Category II Pelvic Blocking and Cranial Protocol
Status: COMPLETED
Conditions: Pain|Sacroiliac Joint Dysfunction
Interventions: PROCEDURE: Category II Pelvic Blocking|PROCEDURE: Category II Pelvic Blocking and Cranial|PROCEDURE: Cranial Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduction of Starvation Time Prior to Gastroscopy
Status: TERMINATED
Conditions: Habile Adult Patients Referred to the Elective Gastroscopy
Interventions: BEHAVIORAL: Group 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Bright Light Therapy on Prader-Willi Syndrome
Status: RECRUITING
Conditions: Prader-Willi Syndrome|Excessive Daytime Sleepiness|Hyperphagia|Body Weight|Mood|Behavior
Interventions: OTHER: Sham Light|OTHER: Bright Light Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Supplemental Selenium and Vitamin E and Pulmonary Function
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Lung Diseases|Lung Diseases, Obstructive
Interventions: DIETARY_SUPPLEMENT: Vitamin E|DIETARY_SUPPLEMENT: Selenium|DIETARY_SUPPLEMENT: Vitamin E placebo|DIETARY_SUPPLEMENT: Selenium placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ThisCART19A for B-NHL Relapsed After Auto-CAR T
Status: RECRUITING
Conditions: CAR|B Cell Lymphoma|Relapsed Non-Hodgkin Lymphoma
Interventions: DRUG: ThisCART19A with Dose Level 1|DRUG: ThisCART19A with Dose Level 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Vibro-tactile Feedback for Patients Who Underwent Lower Limb Amputation
Status: TERMINATED
Conditions: Amputation of Lower Limb Below Knee|Unilateral
Interventions: DEVICE: vibrotactile ground-contact feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long-term Safety in Atrial Fibrillation Patients
Status: COMPLETED
Conditions: Persistent or Permanent Nonvalvular Atrial Fibrillation
Interventions: DRUG: AZD0837|DRUG: VKA INR 2-3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Validation of the Chinese Version of the SECONDs
Status: COMPLETED
Conditions: Minimally Conscious State|Vegetative State
Interventions: DIAGNOSTIC_TEST: Simplified Evaluation of CONsciousness Disorders (SECONDs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Modelling and Control of Non-invasive Vagus Nerve Stimulation for Autoimmune Diseases (1A)
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus|Autoimmune Disorder|Vagus Nerve Autonomic Disorder
Interventions: DEVICE: Parasym 1Hz|DEVICE: Parasym 30Hz|DEVICE: Sham Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Maintaining a Higher Level of Haemoglobin: Effect on the White Cells After Bone Marrow Transplantation in Children.
Status: TERMINATED
Conditions: Neutropenia
Interventions: OTHER: Transfusion level 120 g/dL|OTHER: Transfusion level 70 g/dL|OTHER: Platelet transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Latino Study - A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) and COPEGUS (Ribavirin) in Treatment-Naive Patients With Chronic Hepatitis C-Genotype 1.
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Ribavirin|DRUG: Peginterferon alfa-2a|DRUG: Ribavirin|DRUG: Peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Imaging of Breast Cancer With Breast PET/CT
Status: TERMINATED
Conditions: Breast Cancer
Interventions: RADIATION: Positron emission tomography and computed tomography|RADIATION: Positron emission tomography and computed tomography|RADIATION: Positron emission tomography and computed tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single Portable Pulse-dose-conserving Device vs. Combined Use of Stationary and Portable.
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: Inogen|DEVICE: Combination system of a portable and a stationary device.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Removal of Double Antibiotic Paste on Post Operative Pain
Status: UNKNOWN
Conditions: Effects of the Elements
Interventions: DEVICE: double antibiotic paste with XP-endo Finisher file|DEVICE: double antibiotic paste with Irrisafe Ultrasonic tip|DEVICE: double antibiotic paste with side vented needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Netarsudil Use After Descemetorhexis Without Endothelial Keratoplasty
Status: COMPLETED
Conditions: Fuchs' Endothelial Dystrophy|Cataract
Interventions: DRUG: Netarsudil 0.02% Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT