pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Erlotinib and Sequential Positron Emission Tomography (PET) in Advanced Non Small Cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: erlotinib|PROCEDURE: FDG-/FLT-PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Comparing the Safety of ASP2151 to Valacyclovir and Placebo in Healthy Volunteers
Status: TERMINATED
Conditions: Safety of ASP2151
Interventions: DRUG: ASP2151|DRUG: Valacyclovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Effect of Nordic Recommended Diet on the Features of Metabolic Syndrome - Multicentre Study
Status: COMPLETED
Conditions: Abdominal Obesity|Insulin Resistance|Impaired Glucose Tolerance|Type 2 Diabetes|Cardiovascular Diseases
Interventions: OTHER: Experimental diet|OTHER: Control diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Discomfort Perceived by a Cohort of Patients Treated With Aligners and Attachments Placed According to Two Different Protocols
Status: WITHDRAWN
Conditions: Malocclusion
Interventions: DEVICE: CP - conventional protocol|DEVICE: DP - delayed protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Soy on HDL-C Function, Central Blood Pressure, and Arterial Stiffness
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Soy Protein Powder (25g/d)|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Soy Protein Powder (50g/d)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Using Pre-op Incentive Spirometer Reduces Chances of Basal Atelectasis in Patients Undergoing Upper Abdominal Surgeries
Status: COMPLETED
Conditions: Cholelithiasis|Epigastric Hernia|Duodenal Perforation
Interventions: DEVICE: Pre-Op Incentive Spirometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ultrasound and MRI Measurement of Quadriceps Femoris Muscle in Critically Ill Children
Status: RECRUITING
Conditions: Quadriceps Femoris Measurement as a Surrogate of Muscle Mass Assessment in Critically Ill Children
Interventions: OTHER: Ultrasound and magnetic resonance imaging measurements of quadriceps femoris
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cisplatin to Patients With Pancreatic Cancer and Homologous Recombination Deficiency
Status: RECRUITING
Conditions: Pancreatic Adenocarcinoma|Homologous Recombination Deficiency
Interventions: DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F Fluciclovine (FACBC) PET/CT in Patients With Rising PSA After Initial Prostate Cancer Treatment
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: 18F-fluciclovine PET CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Green Propolis Extract (EPP-AF) on Inflammation in Hemodialysis Patients.
Status: COMPLETED
Conditions: Chronic Kidney Disease Requiring Chronic Dialysis
Interventions: DRUG: Propolis Period (Green Propolis 250mg/day)|OTHER: Control Period
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: mVIP (Use of mHealth Technology for Supporting Symptom Management in Underserved Persons Living With HIV)
Status: COMPLETED
Conditions: HIV (Human Immunodeficiency Virus)
Interventions: DEVICE: Health Management App with symptom strategies|DEVICE: Control App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Performance of a Silicone Hydrogel Contact Lens Following One Night of Extended Wear
Status: COMPLETED
Conditions: Refractive Errors
Interventions: DEVICE: LID011121 contact lens|DEVICE: Comfilcon A contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bariatric Procedures and Changes in Incretins and Gastric Emptying
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: RADIATION: Gastric emptying scintigraphy|OTHER: Determination of gut hormones
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Proning Early in Awake COVID-19 Hypoxic Respiratory Failure (PREACHR) Study
Status: COMPLETED
Conditions: Covid19|Respiratory Failure
Interventions: BEHAVIORAL: Proning|OTHER: Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity, Safety & Reactogenicity of GSK Vaccine Tritanrix™-HepB/Hib2.5 Compared to GSK Vaccine Tritanrix™-HepB/Hiberix™
Status: COMPLETED
Conditions: Haemophilus Influenzae Type b
Interventions: BIOLOGICAL: Tritanrix™-HepB low thio /|BIOLOGICAL: Hib 2.5|BIOLOGICAL: Tritanrix™-HepB|BIOLOGICAL: Hiberix™|BIOLOGICAL: Unconjugated Hib vaccine (plain PRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH)
Status: RECRUITING
Conditions: Cardiovascular Diseases|Infant ALL|Maternal Behavior|Childhood Obesity
Interventions: BEHAVIORAL: Infant Cardiovascular Health (CVH) Promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ciNPT in Autologous DIEP Flap Breast Reconstruction
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Wound Dehiscence, Surgical
Interventions: DEVICE: ciNPT|OTHER: Conventional Tape Dressings|PROCEDURE: DIEP Breast Reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Benefit of Tin Filter in Regards to Image Quality and Radiation Dose in CT Scan Study of Pulmonary Parenchyma
Status: UNKNOWN
Conditions: Tin X Ray|Pulmonary Parenchyma
Interventions: DIAGNOSTIC_TEST: X ray imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Clinical Trial of TQ05105 Tablets Combined With TQB3909 Tablets in the Treatment of Myelofibrosis (MF)
Status: RECRUITING
Conditions: Myelofibrosis
Interventions: DRUG: TQ05105 tablets|DRUG: TQB3909 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Fitness, Body Composition and Frailty in Elderly People.Exercise Program Effecsts. EXERNET Elder 3.0
Status: COMPLETED
Conditions: Frail Elderly Syndrome|Sarcopenia|Physical Activity
Interventions: BEHAVIORAL: Multicomponent exercise programe
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Cerebrolysin Treatment as an add-on Therapy to Mechanical Thrombectomy in Acute Ischemic Stroke.
Status: RECRUITING
Conditions: Stroke, Ischemic|Stroke, Acute|Stroke Sequelae
Interventions: DRUG: Cerebrolysin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of VER-01 in the Treatment of Patients With Chronic Non-specific Low Back Pain
Status: COMPLETED
Conditions: Chronic Non-specific Low Back Pain
Interventions: DRUG: VER-01|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Helicobacter Pylori Eradication in Functional Dyspepsia
Status: COMPLETED
Conditions: Dyspepsia|Helicobacter Pylori Infection
Interventions: DRUG: Clarithromycin 500mg|DRUG: Amoxicillin 1000 MG|DRUG: Pantoprazole 40mg|DRUG: Levosulpiride|DRUG: Acotiamide|DRUG: Itopride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Percutaneous Superior Venae Cava Cannulation Clamping on Cerebral Near Infrared Spectroscopy in MICS
Status: COMPLETED
Conditions: Mitral Regurgitation
Interventions: PROCEDURE: PSVC line clamped
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intermittent Screening and Treatment or Intermittent Preventive Treatment (IPT) With Dihydroartemisinin-Piperaquine, Versus IPT With Sulfadoxine-Pyrimethamine for the Control of Malaria in Pregnancy in Kenya
Status: COMPLETED
Conditions: Pregnancy|Malaria
Interventions: DRUG: IPTp-SP|DRUG: IPTp-DP|DRUG: ISTp-DP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: FeAsiBility of a Treatment Free Interval in Newly Diagnosed MM Patients Treated With Daratumumab-lenalidomide-dexamethasone (HOVON174MM)
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab Injection|DRUG: Dexamethasone|DRUG: Lenalidomide capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D Supplementation on Exercise Adaptations in Patients on Statin Therapy
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DRUG: Vitamin D|DRUG: Simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Blood Flow Restriction on Pain Perception, Grip Strength and Nerve Conductivity in CTS Patients.
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Blood Flow Restriction training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: How To Evaluate The Efficiency And Safety Of Neoadjuvant Chemotherapy In Locally Advanced Cancer Cervix
Status: UNKNOWN
Conditions: Locally Advanced Cervical Carcinoma
Interventions: DRUG: Cis Platinum + Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Use of Potential Predictors of Readmission in Hospitalized Medicine Patients
Status: WITHDRAWN
Conditions: The Focus is to Test a Survey Predicting Readmissions|Inpatient Internal Medicine Patients
Interventions: BEHAVIORAL: Pharmacist services
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Soft Tissue Response to Different Restorative Materials Used in Implant Dentistry
Status: RECRUITING
Conditions: Edentulous Alveolar Ridge|Peri-Implantitis|Peri-implant Mucositis|Prosthetic Infection|Prosthetic Complication
Interventions: DEVICE: Dental Crown with Titanium-Abutment|DEVICE: Dental Crown with PEEK (Polyetheretherketone)-Abutment|DEVICE: Dental Crown with Zirconia-Abutment|DEVICE: Dental Crown with Lithium-Disilicate-Abutment (e.max)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Dexmedetomidine in Acute Stroke and Cerebral Vasospasm Interventions
Status: TERMINATED
Conditions: Stroke|Brain Ischemia|Vasospasm, Intracranial|Hemorrhage, Intracranial
Interventions: DRUG: Dexmedetomidine|DRUG: Fentanyl|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prebiotic Effects in Healthy Toddlers
Status: NOT_YET_RECRUITING
Conditions: Child Development|Diet, Healthy
Interventions: DIETARY_SUPPLEMENT: New prebiotic follow-on formula, randomly assigned to healthy toddlers|DIETARY_SUPPLEMENT: Standard follow-on formula, randomly assigned to healthy toddlers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PreOperative Steroid in Abdominal Wall Reconstruction: A Double-blinded Randomized Clinical Trial
Status: COMPLETED
Conditions: Hernia, Ventral
Interventions: DRUG: Methyl-Prednisolone|DRUG: Physiological saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Weight Loss in Response to Sibutramine (MERIDIA) is Influenced by the Inherited Genes
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: sibutramine|DRUG: sibutramine|DRUG: sibutramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Dose Chemo With Stem Cell Transplant as Treatment for Multiple Sclerosis That Failed Prior Treatment
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: DRUG: Alemtuzumab|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Bifidobacterium on Irritable Bowel Syndrome
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Bifidobacterium breve|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 1 Pilot Study of the Subcutaneous (s.c.) Route to Facilitate the Administration of RRx-001
Status: TERMINATED
Conditions: Malignant Solid Tumor|Lymphomas
Interventions: DRUG: RRx-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Nutritional Intervention and Outcomes of Children Submitted to Heart Surgery for Congenital Heart Diseases
Status: COMPLETED
Conditions: Congenital Heart Disease|Malnutrition
Interventions: DIETARY_SUPPLEMENT: Nutritional intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating Microarray Pharmacogenetic Testing in Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Cancer|Gastrointestinal Cancer
Interventions: GENETIC: Pharmacogenomic Testing with the "Global Diversity Array with Enhanced PGx"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bortezomib, Cyclophosphamide, Dexamethasone, and Thalidomide in Treating Patients With Newly Diagnosed, Previously Untreated Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: bortezomib|DRUG: cyclophosphamide|DRUG: dexamethasone|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FACTS I: A Study to Test the Safety and Effectiveness of a New Medication on the Treatment of Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: OPC-6535 Tablets (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: US-guided Sciatic Nerve Block: Evaluation of the Intraneural Ropivacaine Minimal Effective Volume (MEV90)
Status: COMPLETED
Conditions: US-guided Sciatic Nerve Block
Interventions: PROCEDURE: intraneural sciatic nerve injection|DRUG: Ropivacaine 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strategies to Close the Gap From CC Diagnosis to Treatment in Botswana
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: BEHAVIORAL: Clinic Outreach|BEHAVIORAL: Enhanced Outreach|BEHAVIORAL: Low-Touch Strategy|BEHAVIORAL: High-Touch Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Physiologic Assessment of Thrombus Aspiration in Acute ST-segment Elevation Myocardial Infarction Patients
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: DEVICE: Eliminate aspiration catheter|PROCEDURE: Conventional primary angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Preoperative Administration of Gabapentin in 3rd Molar Dental Extraction.
Status: RECRUITING
Conditions: Dental Pain and Sensation Disorder|Pain, Postoperative
Interventions: DRUG: Gabapentin 600mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Stempeucel® in Patients With Critical Limb Ischemia (CLI) Due to Peripheral Arterial Disease
Status: RECRUITING
Conditions: Critical Limb Ischemia|Peripheral Arterial Disease
Interventions: BIOLOGICAL: Stempeucel®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Capecitabine (Xeloda) in Participants With Locally Advanced or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Capecitabine|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Submental Artery Island Flap Versus Maxillary Obturator Prosthesis
Status: UNKNOWN
Conditions: Patient With Partial Maxillectomy|Submental Island Flap|Maxillary Obturator
Interventions: PROCEDURE: Submental flap for palatal reconstruction|DEVICE: maxillary obturator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: N-acetylcysteine in Liver Transplantation
Status: COMPLETED
Conditions: End Stage Liver Failure
Interventions: DRUG: N-acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Determination of the Optimum Delivery Route for Botulinum Toxin A in Patients With Epiphora
Status: COMPLETED
Conditions: Epiphora
Interventions: DRUG: Botulinum Toxin Type A|DRUG: Botulinum Toxin Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Renogram Study With Percutaneous Nephrolithotomy (PERC): Alterations in Renal Blood Flow as a Consequence of PERC
Status: COMPLETED
Conditions: Renal Calculi
Interventions: OTHER: Renogram
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of a Clinical Pharmacist in Lifestyle Modification in Type 2 Diabetic Patients With Peripheral Neuropathy
Status: UNKNOWN
Conditions: Diabetic Peripheral Neuropathy
Interventions: OTHER: Diabetic patients with neuropathy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Relative Bioavailability Study of Valcyte (Valganciclovir) in Lung Transplant Recipients With or Without Cystic Fibrosis.
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: DRUG: valganciclovir [Valcyte]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability, and Efficacy Study of IBI314 in Patients With Mild to Moderate COVID-19
Status: TERMINATED
Conditions: COVID-19
Interventions: BIOLOGICAL: IBI314(low dose)|BIOLOGICAL: IBI314(high dose)|BIOLOGICAL: IBI314(medium dose)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tonsillectomy and Expansion Sphincter Pharyngoplasty Operations
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Osa Syndrome
Interventions: PROCEDURE: Tonsillectomy|PROCEDURE: Expansion sphincter pharyngoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Yogurt Powder Effect on Bone Health Biomarkers
Status: COMPLETED
Conditions: OSTEOPENIA
Interventions: DIETARY_SUPPLEMENT: Functional yogurt powder|DIETARY_SUPPLEMENT: Control yogurt powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised Trial of Imatinib Alternating With Regorafenib Compared to Imatinib Alone for the First Line Treatment of Advanced Gastrointestinal Stromal Tumour (GIST)
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastrointestinal Stromal Tumour
Interventions: DRUG: Regorafenib|DRUG: imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collaboration Between Department of Old Age Psychiatry and Nursing Homes
Status: COMPLETED
Conditions: Dementia|Alzheimer's Disease|Behavioral Symptoms|Agitation
Interventions: OTHER: Education and Supervision|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Two Different Regional Analgesia Techniques for Patients Undergoing Total Knee Arthroplasty
Status: RECRUITING
Conditions: Analgesia|Arthropathy of Knee|Postoperative Pain
Interventions: PROCEDURE: Selective tibial nerve block|PROCEDURE: IPACK block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROPRANOLOL PLUS LIGATION REDUCES RECURRENCE OF ESOPHAGEAL VARICES?
Status: COMPLETED
Conditions: CIRRHOSIS|ESOPHAGEAL VARICES
Interventions: PROCEDURE: ENDOSCOPIC BAND LIGATION|DRUG: PROPRANOLOL|DEVICE: a multiband ligation device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Adding Paracetamol to Ibuprofen for Treatment of Patent Ductus Arteriosus in Preterm Infants
Status: COMPLETED
Conditions: Ductus Arteriosus, Patent
Interventions: DRUG: Paracetamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Cardiopulmonary Bypass Flow on Cerebral Autoregulation
Status: COMPLETED
Conditions: Cerebral Autoregulation|Cardiopulmonary Bypass|Mean Arterial Pressure
Interventions: PROCEDURE: current versus high pump flow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: BIOmarkers and PLAtelet Function Assessment in Myocardial Ischemia and Non Obstructive Coronary Arteries Study
Status: RECRUITING
Conditions: Ischemia With no Obstructive Coronary Artery Disease
Interventions: OTHER: Data extraction|OTHER: Blood sampling|OTHER: Clinical Follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Whole-Body Vibration Versus Gravity Force Stimulation on Postural Stability in Children With Down Syndrome
Status: UNKNOWN
Conditions: Down Syndrome
Interventions: OTHER: Designed Physical Therapy Program|OTHER: Whole-Body Vibration|OTHER: Gravity Force Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel, Trastuzumab, and Pertuzumab in the Treatment of Metastatic HER2-Positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: pertuzumab in combination with trastuzumab and paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digestive Endoscopy Suite Radiation Controlling Protective Strategies
Status: COMPLETED
Conditions: Radiation Exposure
Interventions: DEVICE: lead-free protective drape containing bismuth and antimony (RADPAD®)|DEVICE: sterile identical sham drape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Insulin Degludec/Insulin Aspart in Patients With T2DM
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin Degludec and Insulin Aspart Injection|DRUG: Insulin Aspart Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Goal-Directed Hemostatic Resuscitation Trial in ACLF Induced Coagulopathy
Status: RECRUITING
Conditions: Acute on Chronic Liver Failure|Variceal Hemorrhage|Cirrhosis, Liver|Thromboelastometry|Thrombosis;Portal
Interventions: DIAGNOSTIC_TEST: Rotational thromboelastometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Universal Screening for Tuberculosis and Anemia With the CHICA System
Status: COMPLETED
Conditions: Tuberculosis|Iron Deficiency Anemia
Interventions: OTHER: CHICA Diagnosis Module|OTHER: CHICA Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial of Paclitaxel and Bevacizumab vs. Gemcitabine, Paclitaxel, and Bevacizumab in Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: gemcitabine|DRUG: paclitaxel|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Neostigmine for Prevention of PDPH
Status: COMPLETED
Conditions: Post-Dural Puncture Headache
Interventions: DRUG: Neostigmine Methylsulfate|DRUG: Dextrose 5% in water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Immunogenicity, Safety, and Tolerability of a Tick-Borne Encephalitis (TBE) Vaccine in Healthy Japanese Participants 1 Year of Age and Older
Status: COMPLETED
Conditions: Tick-Borne Encephalitis
Interventions: BIOLOGICAL: TBE vaccine 0.5 mL|BIOLOGICAL: TBE vaccine 0.25 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Gemcitabine in Combination With Cisplatin as Neoadjuvant NSCLC Chemotherapy
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mono- Versus Dual antiPlatelet Therapy During 6-12 Months After New Generation Drug Eluting Stent Implantation
Status: COMPLETED
Conditions: Gastrointestinal Injury|Ischemic Heart Disease
Interventions: DRUG: Aspirin + clopidogrel|DRUG: Clopidogrel monotherapy|DRUG: Aspirin monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Induction of Labour at Term With Low Dose Oral Misoprostol Versus a Foley Catheter
Status: ACTIVE_NOT_RECRUITING
Conditions: Induction of Labor
Interventions: DRUG: Misoprostol 200mcg Tab|DEVICE: Foley Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of BIIB093 in Participants With Brain Contusion
Status: TERMINATED
Conditions: Brain Contusion
Interventions: DRUG: BIIB093|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 4.5mg PEG-rhG-CSF Per Cycle in Preventing Neutropenia After Intensive Chemotherapy for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Neutropenia
Interventions: DRUG: PEG-rhG-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Study of Nanoencapsulated Gel of Lidocaine, Prilocaine and Combination of Lidocaine and Prilocaine
Status: COMPLETED
Conditions: Topical Anesthesia
Interventions: DRUG: Lidocaine + Prilocaine|DRUG: Lidocaine|DRUG: Prilocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerance by Engaging Antigen During Cellular Homeostasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Transplantation|Renal Transplantation|Renal Transplant Recipient
Interventions: BIOLOGICAL: Donor-derived Mesenchymal Stromal Cells|DRUG: alemtuzumab|DRUG: belatacept|DRUG: sirolimus|DRUG: mycophenolate mofetil|DRUG: mycophenolate acid|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PANACEA Feasibility Study to Assess the Efficacy of BurstDR Spinal Cord Stimulation (SCS)
Status: UNKNOWN
Conditions: Pain
Interventions: DEVICE: Spinal cord stimulation by implanted device.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Anesthesia With Articaine and Lidocaine for Outpatient Surgery.
Status: COMPLETED
Conditions: Spinal Anesthesia
Interventions: DRUG: spinal administration of articaine|DRUG: spinal administration of lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Calcium Silicate Pulp-capping; a Randomized Controlled Clinical Trial
Status: UNKNOWN
Conditions: Reversible Pulpitis
Interventions: RADIATION: Cone Beam computed tomography (Morita Accuitomo)|RADIATION: Periapical radiographs|DEVICE: calcium silicate cement (Biodentine™)|DEVICE: glass ionomer cement ( Fuji IX™)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cranial Electrotherapy Stimulation for the Treatment of Major Depressive Disorder in Adults
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: Fisher Wallace Cranial Electrotherapy Stimulator (Active Device)|DEVICE: Fisher Wallace Cranial Electrotherapy Stimulator (Placebo Device)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of the Kata® Inhalations-App on Inhaler Handling Errors, Adherence, and Asthma Control in Patients With Asthma.
Status: RECRUITING
Conditions: Asthma
Interventions: DEVICE: Kata Inhalations-App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients
Status: RECRUITING
Conditions: Pancreatic Cancer|Gastric Cancer|Gastrointestinal Cancer|Colon Cancer|Rectal Cancer
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: Anti-KRAS G12V mTCR PBL|DRUG: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Mitochondrial Dysfunction in Severe Burn and Trauma Patients
Status: UNKNOWN
Conditions: Burns|Trauma
Interventions: OTHER: trauma: blood collection|OTHER: healthy volunteers: blood collection|OTHER: Burn: blood collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Delayed Cord Clamping at Term Cesarean
Status: COMPLETED
Conditions: Maternal Blood Loss|Cesarean Delivery|Delayed Cord Clamping|Neonatal Health
Interventions: PROCEDURE: Umbilical cord clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Rejuvenation of the Lower Eyelid Using a Combination of Two Hyaluronic Acid Fillers - a Pilot Study
Status: COMPLETED
Conditions: Infraorbital Hollows
Interventions: DRUG: Restalyne|DRUG: Perlane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tonometry Precision and Accuracy During PROSE Scleral Lens Wear: A Pilot Study
Status: COMPLETED
Conditions: Intraocular Pressure and PROSE Lens
Interventions: DIAGNOSTIC_TEST: Intraocular pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multidisciplinary Shared Decision Making of Fertility Preservation in Young Women With Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Young Womenwith Breast Cancer
Interventions: BEHAVIORAL: Counseling to preserve fertility
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tandem DBS for Parkinson's Disease: A Pilot Study Utilizing STN/GPi + Hypothalamic Stimulation
Status: COMPLETED
Conditions: Parkinson's Disease|Deep Brain Stimulation
Interventions: DEVICE: Deep brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vorinostat and IV Fluorouracil/Leucovorin (5FU/LV) in Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Suberoylanilide hydroxamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Home-based Stretching Program on Fibromyalgia Symptoms: a Randomised Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Fibromyalgia|Stretch|Adherence, Treatment
Interventions: OTHER: Home-based stretching exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ⅲa Study of Genetically Modified Recombinant Human Interleukin-11
Status: COMPLETED
Conditions: Chemotherapy-induced Thrombocytopenia
Interventions: DRUG: NL201|DRUG: NL201|DRUG: NL201|DRUG: rhIL-11
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Retreatment of Patients With Non-Hodgkin's Lymphoma Who Have Previously Responded to Iodine-131 Anti B1 Antibody
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: BIOLOGICAL: Tositumomab and Iodine I 131 Tositumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risedronate in the Prevention of Osteoporosis in Postmenopausal Women
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: Risedronate (HMR4003)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An Open-label Study of the Effect of Tomivosertib (eFT508) in Patients With Advanced Castrate-resistant Prostate Cancer
Status: TERMINATED
Conditions: Castrate-resistant Prostate Cancer (CRPC)
Interventions: DRUG: eFT508
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Bilastine on F1 Simulator Driving Performance in Patients Affected by Allergic Rhinitis and/or Urticaria
Status: COMPLETED
Conditions: Allergic Rhinitis|Urticaria
Interventions: DRUG: Bilastine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PRIMADOS Study:A Study of Avastin (Bevacizumab) Plus Docetaxel for First Line Treatment of Patients With Metastatic Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Safety and Preliminary Efficacy of hUC-MSCs Intravenous Infusion Therapy for ARDS
Status: NOT_YET_RECRUITING
Conditions: Acute Respiratory Distress Syndrome
Interventions: DRUG: umbilical cord mesenchymal stem cell|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Family-Based Protocol for Medication Integration in Treatment of Comorbid ASU/ADHD in Routine Care
Status: COMPLETED
Conditions: Adolescent Substance Abuse|Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Medication integration protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spiral Strapping for Improving Upper Limb Functions
Status: RECRUITING
Conditions: Stroke|Splints|Physical Disability
Interventions: DEVICE: TogRite stretch Strapping|OTHER: Traditional upper limb functional exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Tolerability and Efficacy of Bowel Preparation With Split Dose Picosalax vs. Split Dose PEG
Status: TERMINATED
Conditions: Bowel Preparation
Interventions: DRUG: Polyethylene Glycol|DRUG: Picosalax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Testing the Addition of Targeted Radiation Therapy to Surgery and the Usual Chemotherapy Treatment (Pemetrexed and Cisplatin [or Carboplatin]) for Stage I-IIIA Malignant Pleural Mesothelioma
Status: TERMINATED
Conditions: Pleural Biphasic Mesothelioma|Pleural Epithelioid Mesothelioma|Stage I Pleural Malignant Mesothelioma AJCC v8|Stage IA Pleural Malignant Mesothelioma AJCC v8|Stage IB Pleural Malignant Mesothelioma AJCC v8|Stage II Pleural Malignant Mesothelioma AJCC v8|Stage IIIA Pleural Malignant Mesothelioma AJCC v8
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|PROCEDURE: Decortication|RADIATION: Intensity-Modulated Radiation Therapy|DRUG: Pemetrexed|DRUG: Pemetrexed Disodium|RADIATION: Pencil Beam Scanning|PROCEDURE: Pleurectomy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Fat Grafting Versus Subepithelial Connective Tissue Graft for Volume Augmentation
Status: COMPLETED
Conditions: Alveolar Bone Loss
Interventions: OTHER: Autologous fat grafting|OTHER: Sub-epithelial connective tissue graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Trial of Autologous Dendritic Cell Vaccine for Recurrent Ovarian or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Peritoneal Cancer
Interventions: BIOLOGICAL: DCVac-L
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stimulating the Brain to Improve Self-Awareness
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DEVICE: active anodal tDCS|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: IMC-A12 in Treating Young Patients With Relapsed or Refractory Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor or Other Solid Tumor
Status: COMPLETED
Conditions: Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: cixutumumab|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two-stage Treatment of Large Bone Defects With Cerament® G and Cerament® V Plus Auto and/or Allograft Using the Masquelet Technique as Salvage Therapy After Bone Resection in Patients With Septic Pseudarthrosis
Status: RECRUITING
Conditions: Pseudarthrosis
Interventions: OTHER: Cost evaluation|OTHER: Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Show Improved Vision With the HOYA AF-1 Aspheric Intraocular Lens After Cataract Surgery
Status: UNKNOWN
Conditions: Cataracts
Interventions: DEVICE: Hoya AF-1 IOL|DEVICE: Revital vision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panobinostat (LBH589): Multiple Myeloma - Autologous Hematopoietic Cell Transplantation (HCT)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Panobinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of External Vibration on Voice Quality in Muscle Tension Dysphonia Patients and Classically Trained Singers
Status: COMPLETED
Conditions: Dysphonia|Singing
Interventions: DEVICE: Lelo® Siri vibrator|DEVICE: Lelo® Siri vibrator with vibration component removed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Calcitriol on Progress and Activity of Lupus Nephritis
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: calcitriol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Basal-bolus Insulin Therapy Versus Standard Therapy for the Inpatient Management of Type 2 Diabetes: the IDA2 Study
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin Degludec 100 UNT/ML [Tresiba]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesorectal Excision (ME) Versus ME With Lateral Node Dissection for Stage II, III Lower Rectal Cancer (JCOG0212)
Status: COMPLETED
Conditions: Rectal Neoplasms
Interventions: PROCEDURE: Mesorectal excision with lateral lymph node dissection|PROCEDURE: Mesorectal excision without lateral lymph node excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suturing With U-Technique Versus Un-Reapproximated Wound Edges During Removal of Closed Thoracostomy Tube Drain
Status: UNKNOWN
Conditions: Pleural Effusion|Pneumothorax|Chest Trauma|Video-assisted Thoracoscopic Surgery|Thoracotomy|Pleural Diseases|Chylothorax|Empyema|Pyothorax|Thoracic Diseases|Thoracic Injury
Interventions: PROCEDURE: Closure of chest tube wound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Pembrolizumab as Post-Remission Treatment of Patients ≥ 60 With AML
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effectiveness of Intravitreal (IVT) Aflibercept Injection in Clinical Practice in naïve Patients With Neovascular Age-related Macular Degeneration (nAMD)
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: Eylea (Aflibercept, VEGF Trap-Eye, BAY86-5321)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p