pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of ASP8273 in Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor-Naïve Patients With Non-Small Cell Lung Cancer Harboring EGFR Mutations
Status: TERMINATED
Conditions: EGFR-TKI-naïve Patients With NSCLC Harboring EGFR Activating Mutations
Interventions: DRUG: ASP8273 Capsules|DRUG: ASP8273 Capsules A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Efficacy of Microwave vs Embolization Treatment for Adenomyosis
Status: RECRUITING
Conditions: Adenomyosis
Interventions: PROCEDURE: Microwave treatment via needle antenna|PROCEDURE: Embolization of uterine artery or branches thereof (routine treatment where polyvinyl alcohol particles are released into the predefined bloodstream)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Transcutaneous Vagal Nerve Stimulation on Stress Response in Major Depression
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: active tVNS|DEVICE: Sham tVNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Study of Nizatidine Capsules 300 mg of Dr.Reddy's Laboratories Limited Under Non- Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nizatidine|DRUG: Axid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective OCT Study With Lucentis for Neovascular AMD (PrONTO Study)
Status: COMPLETED
Conditions: Neovascular Age-Related Macular Degeneration
Interventions: DRUG: Lucentis (Ranibizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics, Respiratory and Intestinal Microbiome and Respiratory Tract Infections in Children
Status: UNKNOWN
Conditions: Respiratory Infections in Children
Interventions: COMBINATION_PRODUCT: Bacillus clausii|OTHER: Sterile water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Liatermin (r-metHuGDNF) Administered by Bilateral Intraputaminal (IPu) Infusion to Subjects With Idiopathic Parkinson's Disease
Status: COMPLETED
Conditions: Idiopathic Parkinson's Disease
Interventions: DRUG: Liatermin (r-metHuGDNF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Dose Escalation Trial of PR104 Given Weekly in Subjects With Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: PR104
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone, Aspirin, and Diethylstilbestrol in Treating Patients With Locally Advanced or Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: acetylsalicylic acid|DRUG: dexamethasone|DRUG: diethylstilbestrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Clinical Comparison of Two Daily Disposable Toric Soft Contact Lenses
Status: COMPLETED
Conditions: Astigmatism|Ametropia|Myopia
Interventions: DEVICE: Verofilcon A toric soft contact lenses|DEVICE: Stenfilcon A toric soft contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Outcomes for After Cancer Health
Status: RECRUITING
Conditions: Ovarian Cancer|Breast Cancer|Lung Cancer|Gastric Cancer|Survivorship
Interventions: BEHAVIORAL: Digital Health Coaching Program|DEVICE: Fitbit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combining CRLX101, a Nanoparticle Camptothecin, With Enzalutamide in People With Progressive Metastatic Castration Resistant Prostate Cancer Following Prior Enzalutamide Treatment
Status: TERMINATED
Conditions: Metastatic Castration Resistant Prostate Cancer|Prostate Neoplasms
Interventions: DRUG: enzalutamide|DRUG: CRLX101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caprylic Triglyceride for Treatment of Cognitive Impairments in Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing Remitting MS|Secondary Progressive MS|Primary Progressive MS
Interventions: DIETARY_SUPPLEMENT: Caprylic Triglyceride|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life With Arcoxia in Women With Dysmenorrhea (0663-094)
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: MK0663, Arcoxia, etoricoxib / Duration of Treatment: 3 Days
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study to Determine if RTB101 Reduces the Severity of COVID-19 in Older Adults Residing in Nursing Homes
Status: TERMINATED
Conditions: COVID19
Interventions: DRUG: RTB101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Antibiotic Treatment and Intravenous Immunoglobulin Trial for PANDAS
Status: WITHDRAWN
Conditions: Pandas
Interventions: DRUG: Sertraline+Antibiotic (penicillin/azithromycin)|DRUG: Sertraline+placebo|BIOLOGICAL: IVIG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of SEARCH, a Novel Hierarchical Algorithm to Define Long-term Outcomes After Pulmonary Embolism
Status: ENROLLING_BY_INVITATION
Conditions: Pulmonary Embolism|Chronic Thromboembolic Pulmonary Hypertension
Interventions: OTHER: SEARCH algorithm
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate Safety and Tolerability of QLS-101 in NTG
Status: COMPLETED
Conditions: Normal Tension Glaucoma (NTG)
Interventions: DRUG: QLS-101|DRUG: Timolol maleate PF 0.5% ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Lumacaftor-ivacaftor on Glucose Handling and Tolerance in Cystic Fibrosis Phe508del
Status: WITHDRAWN
Conditions: Diabetes|Cystic Fibrosis
Interventions: DRUG: Lumacaftor-ivacaftor|OTHER: OGTT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Endovascular Therapy for Low NIHSS Ischemic Strokes
Status: RECRUITING
Conditions: Cerebral Ischemia
Interventions: DEVICE: Immediate mechanical thrombectomy(iMT) using EmboTrap Revascularization Device|COMBINATION_PRODUCT: Initial medical management (iMM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Distraction Technique on Children's Pain, Anxiety and Fear of Medical Procedure in Invasive Interventions
Status: COMPLETED
Conditions: Child Behavior
Interventions: OTHER: Kaleidoscope|OTHER: Music|OTHER: Virtual reality glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oxytocin vs. Prostaglandin for Induction of Labor in Primiparas With Prelabor Rupture of Membrane and Low Bishop
Status: UNKNOWN
Conditions: Premature Rupture of Fetal Membranes
Interventions: DRUG: Oxytocin|DRUG: Prostaglandin E2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: USG PECS vs LIA for Breast Cancer Surgery
Status: COMPLETED
Conditions: Breast Cancer Female
Interventions: PROCEDURE: USG PECS2 with Drug A (active)|PROCEDURE: USG PECS2 with Drug P (placebo)|PROCEDURE: Wound infiltration with Drug P (placebo)|PROCEDURE: Wound infiltration with Drug A (active)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Systemic Impact of Trace Elements Release by Implantable Medical Devices. Identification of Biomarkers of Systemic Inflammation
Status: COMPLETED
Conditions: Biomarker|Systemic Inflammation
Interventions: OTHER: Blood, urine, hair, synovial fluid and peri-prosthetic tissue collections|OTHER: Autopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: SC1011 Twice Daily vs Placebo in Patients Diagnosed With Idiopathic Pulmonary Fibrosis (IPF)
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: SC1011|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CONTINUation of Enteral Nutrition Prior to Extubation Compared to Standard Care
Status: RECRUITING
Conditions: Critical Illness
Interventions: OTHER: EN will be continued up to extubation (EN will not be withheld prior to extubation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Improving Veteran Adherence to Treatment for PTSD Through Partnering With Families
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Family Supported Prolonged Exposure|BEHAVIORAL: Standard Prolonged Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Therapy in Patients With Stages IB, II, IIIA, and Selected IIIB Patients With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Docetaxel|DRUG: Gemcitabine|DRUG: Carboplatin|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Of Tocotrienol a Natural Vitamin E In Biopsy Wound
Status: UNKNOWN
Conditions: Scar
Interventions: DEVICE: Topical Tocotrienol (TCT)|DIETARY_SUPPLEMENT: Oral Tocotrienol Capsules (TCT)|DEVICE: Tamoxifen Cream|DEVICE: Placebo cream|DIETARY_SUPPLEMENT: placebo capsule
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study of TQC2731 Injection in the Treatment of Chronic Rhinosinusitis With Nasal Polyps
Status: RECRUITING
Conditions: Chronic Sinusitis|Nasal Polyps
Interventions: DRUG: TQC2731 injection|DRUG: TQC2731 matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of a Nutritional Tool During Melphalan Autologous Transplant to Improve Caloric and Protein Intake
Status: COMPLETED
Conditions: Melphalan Autologous Transplant
Interventions: OTHER: Specialized menu|OTHER: Standard of care menu|OTHER: Self report dietary intake worksheet|OTHER: Post study questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Efficacy and Safety Study of Oxybutynin Chloride Oral Osmotic Therapeutic System (OROS) in Korean Overactive Bladder Participants
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: Oxybutynin chloride OROS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Red Blood Cell Transfusion on Brain Metabolism in Patients With Subarachnoid Hemorrhage
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage|Vasospasm
Interventions: BIOLOGICAL: Red blood cell transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lot-to-lot Consistency of an Inactivated SARS-CoV-2 Vaccine for Prevention of COVID-19 in Healthy Adults
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Inactivated SARS-CoV-2 Vaccine (Vero cell）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Celecoxib Versus Placebo in the Treatment of Patients With Osteoarthritis of the Knee Who Were Unresponsive to Naproxen and Ibuprofen
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Celecoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ibuprofen With or Without Dexamethasone for Acute Radicular Low Back Pain.
Status: RECRUITING
Conditions: Radiculopathy, Lumbosacral Region|Back Pain With Radiation|Low Back Pain
Interventions: DRUG: Ibuprofen 400 mg|DRUG: Dexamethasone Oral|BEHAVIORAL: Educational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Follow Up Study Of Subjects Who Participated In An Original Protocol Of Exemestane Vs. Megestrol Acetate In Postmenopausal Women With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Megestrol acetate|DRUG: exemestane (Aromasin)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CDX-3379 and Cetuximab and in Patients With Advanced Head and Neck Squamous Cell Carcinoma
Status: TERMINATED
Conditions: Advanced Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: CDX-3379 and cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pasireotide LAR Therapy of Silent Corticotroph Pituitary Tumors
Status: TERMINATED
Conditions: Pituitary Tumor|ACTH-producing Pituitary Tumour
Interventions: DRUG: Pasireotide LAR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research on Clinical Safety and Effectiveness of Wearable Assistive Devices With Flexible Structure for Daily Life Support of Stroke Patients
Status: COMPLETED
Conditions: Stroke|Hemiplegia
Interventions: DEVICE: Soft Wearable Robot
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Intravenous Iron Repletion on Renal Function in Patients With Iron Deficiency and Acute Kidney Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Anemia, Iron Deficiency|Acute Kidney Injury
Interventions: DRUG: Iron dextran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Iron Frequency for Childhood Restless Leg Syndrome/Periodic Limb Movement Disorder
Status: TERMINATED
Conditions: Sleep Disorder|Restless Legs Syndrome|Periodic Limb Movement Sleep Disorder|Iron-deficiency
Interventions: DRUG: Ferrous sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Combination of Bifidobacterium Longum 35624® and 1714™ Strains in Adults With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: IBS - Irritable Bowel Syndrome|Depression, Anxiety
Interventions: DIETARY_SUPPLEMENT: Probiotic capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin Hydrochloride Liposome and Bortezomib in Treating Patients With Refractory Hematologic Cancer or Malignant Solid Tumor or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Ovarian Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: PS-341|DRUG: Doxil|DRUG: Velcade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Trial of the Safety, Tolerability and Efficacy of TransCon hGH Weekly Versus Daily hGH in Children With Growth Hormone Deficiency (GHD)
Status: COMPLETED
Conditions: Growth Hormone Deficiency, Pediatric|hGH (Human Growth Hormone)|Endocrine System Diseases|Hormones|Pituitary Diseases
Interventions: DRUG: Once weekly subcutaneous injection of TransCon hGH|DRUG: Once daily subcutaneous injection of Genotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dutasteride Soft Capsule 0.5 mg Relative to Avodart 0.5 mg Soft Capsule
Status: NOT_YET_RECRUITING
Conditions: Healthy Subjects
Interventions: DRUG: Dutasteride-Test product|DRUG: Dutasteride-Reference product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Occlusal Splint and Masticatory Muscle Injection in Myofacial Pain
Status: COMPLETED
Conditions: Myofacial Pain
Interventions: DEVICE: Occlusal splint treatment|PROCEDURE: Masticatory muscle injection|COMBINATION_PRODUCT: Combination of occlusal splint and masticatory muscle injection treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of Topical Menthol on Neck Pain
Status: TERMINATED
Conditions: Musculoskeletal Disorders
Interventions: OTHER: Biofreeze|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Povidone Iodine to Reduce Pulmonary Infection in Head Trauma and Cerebral Hemorrhage in Intensive Care Unit
Status: TERMINATED
Conditions: Ventilator Associated Pneumonia
Interventions: DRUG: povidone iodine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiation Therapy With or Without Cetuximab in Treating Patients With Stage III or Stage IV Cancer of the Oropharynx, Hypopharynx, or Larynx
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: cetuximab|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Enhance Adherence to Multiple Guidelines
Status: COMPLETED
Conditions: Asthma|Cardiovascular Diseases|Atherosclerosis|Diabetes Mellitus|Heart Diseases|Hypertension|Lung Diseases
Interventions: OTHER: practice guideline adherence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Additional Consolidative Esophagectomy for the Patients With Oligometastatic Resectable ESCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma|Oligometastatic Disease
Interventions: PROCEDURE: Esophagectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Pharmacokinetic Characteristics and Safety/Tolerability of YNP-1807 Compared to Lyrica® After Oral Administration Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lyrica 150Mg Capsule|DRUG: YNP-1807 330Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nursing Intervention for the Reduction of Anxiety During the Process of Primary Total Hip Arthroplasty Within the Optimized Recovery Program.
Status: RECRUITING
Conditions: Osteoarthrosis|ERAS|Anxiety|Nurse
Interventions: BEHAVIORAL: video|BEHAVIORAL: Traditional information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intravaginal LACTIN-V for Prevention of Recurrent Urinary Tract Infection
Status: COMPLETED
Conditions: Urinary Tract Infection
Interventions: DRUG: Lactin-V|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Glutamatergic Mechanisms: Aim2
Status: SUSPENDED
Conditions: Healthy
Interventions: DRUG: Ketamine|DRUG: Ts-134|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Galantamine to Potentiate the Attention-Enhancing Effects of Low-Dose Nicotine
Status: COMPLETED
Conditions: Basic Science Study of the Mechanisms of Attentional Enhancement by Compounds Acting on the Nicotinic Receptor
Interventions: DRUG: Placebo patch & placebo capsule|DRUG: Placebo patch & galantamine capsule|DRUG: Nicotine patch & placebo capsule|DRUG: Nicotine patch and galantamine capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: NG101 AAV Gene Therapy in Subjects With Wet Age-Related Macular Degeneration
Status: RECRUITING
Conditions: Age-Related Macular Degeneration
Interventions: GENETIC: NG101 AAV gene therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In-vivo Efficacy and Safety of Artemether/Lumefantrine Vs Dihydroartemisinin-piperaquine for Treatment of Uncomplicated Malaria and Assessment of Parasite Genetic Factors Associated With Parasite Clearance or Treatment Failure
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Artemether-lumefantrine|DRUG: Dihydroartemisinin-piperaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Efficacy and Safety of 'INNOCELL Immuncell-LC' With Temozolomide in Newly Diagnosed Glioblastoma of Korea
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: Activated T lymphocyte(Immuncell-LC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2 Study of Tivozanib in Combination With Nivolumab in Subjects With RCC
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Tivozanib|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of BDB-001 Injection in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BDB-001 injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Topical C-82 in a Psoriasis Plaque Test
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: C-82 Topical Gel, Placebo|DRUG: C-82 Topical Gel, 1%|DRUG: Daivonex cream|DRUG: Diprosis gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Whether Cancers With Specific Mutations Respond Better to Glutaminase Inhibitor, Telaglenastat Hydrochloride, Anti-Cancer Treatment, BeGIN Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm|NF1 Mutation Positive Malignant Peripheral Nerve Sheath Tumor|Unresectable Malignant Solid Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|OTHER: Pharmacodynamic Study|PROCEDURE: Positron Emission Tomography|DRUG: Telaglenastat Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DaTSCAN Imaging in Aging and Neurodegenerative Disease
Status: ENROLLING_BY_INVITATION
Conditions: Dementia|Parkinsonism|Mild Cognitive Impairment|REM Sleep Behavior Disorder
Interventions: DRUG: I-123 Ioflupane solution injection prior to SPECT scan (DaTscan)|DEVICE: Single photon emission computed tomography (SPECT) scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of MCT Emulsification on Ketogenesis in Human Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: MCT oil 10g|DIETARY_SUPPLEMENT: MCT homogenate 10g|DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: MCT oil 20g|DIETARY_SUPPLEMENT: MCT homogenate 20g|DIETARY_SUPPLEMENT: MCT oil 30g|DIETARY_SUPPLEMENT: MCT homogenate 30g
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate Safety and Tolerability After Oral Dosing of AZD1656 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD1656|DRUG: AZD1656
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Existing Wearers of Avaira Sphere Following a Refit With Clariti Elite Sphere
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: somofilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of BEBT-109 in Subjects With Non-Small Cell Lung Cancer Carrying EGFR Exon 20 Insertion Mutations
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: BEBT-109 Capsules|DRUG: Pemetrexed Disodium for Injection|DRUG: Carboplatin Injection|DRUG: Cisplatin Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study of RO4929097 in Patients With Recurrent or Refractory Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: RO4929097|DRUG: RO4929097
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enpatoran Human Mass Balance and Absolute Bioavailability Study
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Enpatoran|DRUG: [14C]enpatoran microtracer|DRUG: [14C]enpatoran microdose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strengthening Families Program Online
Status: ACTIVE_NOT_RECRUITING
Conditions: Substance Abuse
Interventions: BEHAVIORAL: Strengthening Families Program Online eLearning Game|BEHAVIORAL: SFP Home-use DVD|BEHAVIORAL: Wait-Listed Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Abatacept for the Treatment of Myositis-associated Interstitial Lung Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Myositis|Interstitial Lung Disease
Interventions: DRUG: Abatacept|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of SPN-812 (Viloxazine Extended-release Capsule) in Children With ADHD
Status: COMPLETED
Conditions: Attention-Deficit/Hyperactivity Disorder (ADHD)
Interventions: DRUG: Placebo|DRUG: 100mg SPN-812|DRUG: 200mg SPN-812|DRUG: 300mg SPN-812|DRUG: 400mg SPN-812
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac REperfusion With Intralipid® at Reperfusion
Status: UNKNOWN
Conditions: Reperfusion Injury
Interventions: DRUG: Intralipid 20%|DRUG: Modified Ringers Lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female Athletes
Status: COMPLETED
Conditions: ACL Injury
Interventions: OTHER: Neuromuscular Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lapatinib Versus Placebo Given Concurrently With Cisplatin And Radiotherapy In Patients With Unresected Head And Neck Cancer
Status: COMPLETED
Conditions: Neoplasms, Head and Neck
Interventions: DRUG: Lapatinib oral tablets|DRUG: radiotherapy|DRUG: cisplatin chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Dexmedetomidine to Reduce Emergence Delirium Incident in Children
Status: COMPLETED
Conditions: Agitation|Anesthesia|Pediatrics
Interventions: DRUG: Dexmedetomidine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Peritoneal Dialysis in Patients With Refractory Heart Failure and Chronic Kidney Disease
Status: COMPLETED
Conditions: Refractory Heart Failure|Chronic Kidney Disease
Interventions: DRUG: Peritoneal dialysis (PD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Resin Cement Composition on the Longevity of Intraradicular Post of Endodontically Treated Teeth
Status: UNKNOWN
Conditions: MTA|Endodontically Treated Teeth|Resin Cement
Interventions: PROCEDURE: Absolute isolation|PROCEDURE: Manipulation of the resin cement with MTA|PROCEDURE: Manipulation of the resin cement without MTA|PROCEDURE: Fiber Post cimentation|PROCEDURE: Dental Prepare|PROCEDURE: Dental impression|PROCEDURE: Crown cimentation|PROCEDURE: Occlusal adjustment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Intravenous Iron Isomaltose Anhydride for IDA
Status: NOT_YET_RECRUITING
Conditions: Iron Deficiency Anemia
Interventions: DRUG: Intravenous iron isomaltose anhydride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ambulatory Closed-loop Stimulation for Bladder Control
Status: ENROLLING_BY_INVITATION
Conditions: Urinary Bladder, Neurogenic
Interventions: DEVICE: Noninvasive electrical stimulation of genital nerves
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3-Fatty Acid on Joint Symptoms Inducted by Aromatase Inhibitors
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DIETARY_SUPPLEMENT: Omega-3 Fatty Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tavilermide Ophthalmic Solution for the Treatment of Dry Eye
Status: COMPLETED
Conditions: Keratoconjunctivitis Sicca|Dry Eye
Interventions: DRUG: Tavilermide ophthalmic solution|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PEMOCS: Personalized Motor-cognitive Training in Chronic Stroke
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke
Interventions: OTHER: Concept-guided, personalized, motor-cognitive training by means of an exergame
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of HBM Based Education on Glycemic Control of Type 2 Diabates Patients
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Health Belief Model and Health Literacy Level based Education and Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: OTL-200 in Patients With Late Juvenile Metachromatic Leukodystrophy (MLD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Lysosomal Storage Diseases|Metachromatic Leukodystrophy
Interventions: GENETIC: OTL-200
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Immunogenicity Parameters After Vaccination Against Influenza and to Evaluate How These Parameters Change During the Influenza Season
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Inflexal V
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase II Study of Carfilzomib in Relapsed Waldenström's Macroglobulinemia (WM) IST-CAR-531
Status: COMPLETED
Conditions: Waldenstrom Macroglobulinemia
Interventions: DRUG: Carfilzomib|DRUG: Rituximab|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of a Mobile Application in Postoperative Rehabilitation
Status: NOT_YET_RECRUITING
Conditions: Spine Degeneration|Hip Arthritis|Knee Osteoarthritis|Hip Fractures
Interventions: DEVICE: App for in-bed conditioning exercises|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 3 Open Label Extension Study of Fostamatinib Disodium in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia
Status: ENROLLING_BY_INVITATION
Conditions: Warm Antibody Autoimmune Hemolytic Anemia
Interventions: DRUG: Fostamatinib disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Adjuvanted Hepatitis B Vaccine to Double Dose of Engerix™-B in Pre- /Haemodialysis Patients Aged ≥15 Years
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: Hepatitis B adjuvanted vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Acupuncture for Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: PROCEDURE: Acupuncture|OTHER: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PSMA-PET Imaging for Detecting Early Metastatic Prostate Cancer in Men w/ High Decipher Test Scores
Status: RECRUITING
Conditions: Prostate Cancer|Recurrent Prostate Cancer
Interventions: DRUG: F-DCFPyL Injection|DIAGNOSTIC_TEST: PSMA PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The E-SERIES Registry for Supralimus® Coronary Stent for the Treatment of Unselected Patients With Coronary Lesions
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Supralimus® Sirolimus-Eluting Coronary Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Blended Indoor and Outdoor Physical Exercise Program on Depressive Symptoms in Hong Kong Older Adults
Status: RECRUITING
Conditions: Depressive Symptoms
Interventions: BEHAVIORAL: Blended indoor and outdoor multicomponent structured exercise|BEHAVIORAL: Indoor-only multicomponent structured exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First-in-Human Study of SBP-9330 in Healthy Subjects
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: SBP-9330|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Different Pain and Anxiety Reducing Methods in Adult Patients Undergoing Bone Marrow Puncture
Status: COMPLETED
Conditions: Patients Undergoing Puncture of the Bone Marrow
Interventions: DRUG: Midazolam (sedative)|DRUG: Piritramid (analgetic)|BEHAVIORAL: Cognitive exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: ABT-450 With Ritonavir and ABT-267 and/or ABT-333 With and Without Ribavirin in Genotype 1 Hepatitis C Virus Infected Patients
Status: COMPLETED
Conditions: Chronic Hepatitis C|Hepatitis C (HCV)|Hepatitis C Genotype 1
Interventions: DRUG: ABT-450|DRUG: ABT-333|DRUG: ABT-267|DRUG: Ribavirin|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and Liposomal Doxorubicin Chemotherapy With Enoxaparin in Patients With Advanced Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: Docetaxel|DRUG: Liposomal Doxorubicin|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Calcipotriol Plus Betamethasone Gel in the Treatment of Scalp Psoriasis
Status: COMPLETED
Conditions: Psoriasis of Scalp
Interventions: DRUG: Calcipotriol plus betamethasone dipropionate (LEO80185 gel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Tolerability of the On-demand Use of Combined Dapoxetine With Tadalafil and Combined Dapoxetine With Lidocaine 5% Spray in Treatment of Patients With Lifelong Premature Ejaculation and Non-responding to Dapoxetine Alone.
Status: UNKNOWN
Conditions: Premature Ejaculation
Interventions: DRUG: Tadalafil and Combined Dapoxietine|DRUG: Dapoxietine and Combined Lidocaine 5% Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Memory Preservation of Hippocampal Avoidance Whole Brain Radiotherapy
Status: UNKNOWN
Conditions: Brain Metastases|Neurocognitive Function
Interventions: RADIATION: Hippocampal avoidance whole brain radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigation of the Effects of Stabilization Exercises and Pelvic Floor Muscle Training on Pain and Urinary Parameters in Individuals With Chronic Low Back Pain With Urinary Incontinence
Status: NOT_YET_RECRUITING
Conditions: Low Back Pain|Urinary Incontinence
Interventions: BEHAVIORAL: Pelvic floor muscle training combined with stabilization exercises|BEHAVIORAL: Pelvic floor muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Compare the Pharmacokinetic Characteristics of CKD-395 0.25/750 mg in Healthy Male Volunteers
Status: COMPLETED
Conditions: Diabetes Mellitus, Type II
Interventions: DRUG: Duvie Tab. 0.5mg, Glucodaun OR Tab. 750mg|DRUG: CKD-395 0.25/750mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Validity and Reliability of the Turkish Version of TASC and the Relationship Between SMC and Motor Functions
Status: COMPLETED
Conditions: Cerebral Palsy, Spastic|Cerebral Palsy|Cerebral Palsy Spastic Diplegia|Cerebral Palsy Quadriplegic|Cerebral Palsy, Monoplegic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Attune With TruMatch TM Personalized Solutions Instruments
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Osteoarthritis
Interventions: DEVICE: Attune TruMatch (TM) Patient-Specific Instrumentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MRI Compatible and Long-term LFP Recordable Deep Brain Stimulation on PD Patients
Status: UNKNOWN
Conditions: Idiopathic Parkinson Patients
Interventions: DEVICE: 3T MRI compatible and LFP recordable G106R of Beijing Pins medical.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetes-specific Formula (DSF) in Individuals With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: DSF|OTHER: Breakfast 1|OTHER: Breakfast 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Geriatric-CO-mAnagement for Cardiology Patients in the Hospital
Status: COMPLETED
Conditions: Geriatric Assessment|Health Services for the Aged|Cardiovascular Diseases|Activities of Daily Living|Delirium|Frail Elderly|Length of Stay
Interventions: OTHER: Cardio-geriatric co-management
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Depakote ER for the Treatment of Mania in Children Ages 6-12 With Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder|Mania
Interventions: DRUG: divalproex sodium extended release
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Uterotonic Agents on Isolated Human Myometrium
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Oxytocin|DRUG: Ergonovine|DRUG: Carboprost|DRUG: Oxytocin and Ergonovine|DRUG: Oxytocin and Carboprost
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychoeducation, Relaxation, PrOblem Solving, Activation, Cognitive Coping Therapy for Adolescents and Youth in HIV Care
Status: NOT_YET_RECRUITING
Conditions: Depression, Anxiety|Trauma|HIV-1-infection
Interventions: BEHAVIORAL: Psychoeducation, Relaxation, PrOblem solving, Activation, Cognitive coping Therapy|BEHAVIORAL: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Dose Escalation Study of VS-5584 Administered in Combination With VS-6063, in Subjects With Relapsed Malignant Mesothelioma
Status: TERMINATED
Conditions: Relapsed Malignant Mesothelioma
Interventions: DRUG: VS-5584 and VS-6063
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating App-Based Vision Testing (WHOeyes) Combined With the Questionnaire as a Substitute for One-Week Postoperative In-Clinic Follow-Up in Age-Related Cataract Patients: A Multi-center Randomized Controlled Trial
Status: RECRUITING
Conditions: Cataract Senile
Interventions: BEHAVIORAL: WHOeyes combined with a questionnaire.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Web Application Support Versus Standard Management on Compliance With Adjuvant Hormone Therapy at 18 Months in Patients Treated for Breast Cancer
Status: RECRUITING
Conditions: Web-application|Breast Cancer|Hormono Therapy
Interventions: OTHER: WEB-Application|OTHER: Standard accompaniment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Iodine I 131 Monoclonal Antibody 3F8 and Bevacizumab in Treating Patients With Relapsed or Refractory Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: bevacizumab|BIOLOGICAL: filgrastim|PROCEDURE: autologous hematopoietic stem cell transplantation|RADIATION: iodine I 131 monoclonal antibody 3F8
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT