pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of Two Different Doses of ABT-378/Ritonavir in HIV-Infected Patients Who Have Taken Protease Inhibitors and Non-Nucleoside Reverse Transcriptase Inhibitors
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lopinavir/ritonavir|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastro-protective Effect and Pain Relief Effect of Naxozol Compared to Celecoxib in Patients With Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DRUG: Naproxen/Esomeprazol 500/20mg|DRUG: Celecoxib 200mg|DRUG: Naxozol-Placebo|DRUG: Comparator-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Effects of EVOO in Healthy Reproductive-aged Women
Status: UNKNOWN
Conditions: Hypertension|Vascular Stiffness
Interventions: DIETARY_SUPPLEMENT: Extra Virgin Olive Oil|DIETARY_SUPPLEMENT: Control Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Safety and Efficacy in BEY1107 in Monotherapy Gemcitabine Combination in Patient With Pancreatic Cancer
Status: UNKNOWN
Conditions: Locally Advanced or Metastatic Pancreatic Cancer
Interventions: DRUG: BEY1107|COMBINATION_PRODUCT: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ICNBs for Post-op Pain in Breast Surgery
Status: UNKNOWN
Conditions: Pain, Postoperative|Length of Stay
Interventions: DRUG: Bupivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Kangaroo Mother Care With Plastic Bag (Trials 1A & 1B)
Status: WITHDRAWN
Conditions: Preterm Birth|Hypothermia, Newborn
Interventions: OTHER: KMC & WHO protocol (0-1 hour)|OTHER: KMC, WHO protocol & bag (0-1 hour)|OTHER: KMC & WHO protocol (1-24 hours)|OTHER: KMC, WHO protocol & bag (1-24 hours)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Feasibility and Safety of MiWEndo-assisted Colonoscopy
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Polyp|Colorectal Adenoma|Colorectal Neoplasms|Colorectal Adenomatous Polyp|Colorectal Adenocarcinoma
Interventions: DEVICE: MiWEndo-assisted colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Pain, Learning, and Nocebo
Status: COMPLETED
Conditions: Chronic Pain|Pain Syndrome
Interventions: DRUG: D-cycloserine|BEHAVIORAL: Conditioning|BEHAVIORAL: Extinction|OTHER: fMRI|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Test 2 Treat: Can we Improve the Testing and Treatment of High Cholesterol in Patients Who Have Been Hospitalized for a Cardiac Event by Providing Education to Doctors and Patients?
Status: NOT_YET_RECRUITING
Conditions: ASCVD|LDL-C
Interventions: OTHER: Care Champion Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Probiotic Lozenges for Treatment of Recurrent Aphthous Stomatitis
Status: COMPLETED
Conditions: Oral Ulcer
Interventions: OTHER: Probiotics|DRUG: Oracure oral gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The KHENERGYC Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Mitochondrial Diseases|Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation|MELAS|Subacute Necrotizing Encephalomyelopathy
Interventions: DRUG: Sonlicromanol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Access the Effect of Brain Pill™ on Working Memory Capacity and Mood Behaviour.
Status: COMPLETED
Conditions: Memory Dysfunction|Mood Disorders
Interventions: DIETARY_SUPPLEMENT: Cognizin® SynapsaTM|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of the Drug B11-FC (Botulism Treatment)
Status: NOT_YET_RECRUITING
Conditions: Botulism
Interventions: DRUG: B11-FC|DRUG: Botulinum neurotoxin type A|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Significance of Single Center, Open and Prospective Evaluation of <Sup>18<Sup>F-FDG PET/CT Dynamic Imaging and Genomic Sequencing in Detecting Metastatic Lesions and Differentiating Multiple Primary Lung Cancer From Intrapulmonary Metastases of Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Positron-Emission Tomography|Non-small Cell Lung Cancer
Interventions: DIAGNOSTIC_TEST: PET/CT dynamic scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Remote Ischemic Conditioning in Patients With Spontaneous Intracerebral Hemorrhage
Status: NOT_YET_RECRUITING
Conditions: Intracranial Hemorrhages
Interventions: PROCEDURE: Remote ischemic conditioning|PROCEDURE: Sham remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRIMETEST II - Clinical Stage II A/B Seminoma Treated With RA-RPLND
Status: RECRUITING
Conditions: Seminoma
Interventions: PROCEDURE: Robot-assisted retroperitoneal lymph node dissection|DRUG: Adjuvant therapy with one cycle of cisplatin, etoposide and bleomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular and Cellular Mechanism in the Course of Immunotherapy With a Phleum Pratense Oral Lyophilisate
Status: COMPLETED
Conditions: Allergic Rhinitis Due to Grass Pollens
Interventions: DRUG: Grazax|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of the Efficacy and Safety of Lonidamine for the Treatment of Symptomatic Benign Prostatic Hyperplasia
Status: TERMINATED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Lonidamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pilates Method and/or Photobiomodulation in Women With Stress Urinary Incontinence
Status: COMPLETED
Conditions: Laser Therapy|Urinary Incontinence,Stress|Pilates Method
Interventions: OTHER: Pilates|OTHER: Photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Asenapine Compared With Olanzapine in Patients With Persistent Negative Symptoms of Schizophrenia (25543)(COMPLETED)(P05817)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: asenapine|DRUG: olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SPEL as Introductive Treatment Following Immune-chemotherapy as Consolidated Therapy for R/R DLBCL With p53 and/or c-Myc Expression
Status: NOT_YET_RECRUITING
Conditions: DLBCL
Interventions: COMBINATION_PRODUCT: Selinexor combined with Prednisone, Etoposide, and Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Protection Conservative Effects of Esketamine Versus µ-opioid Receptor Agonists in General Anesthesia
Status: RECRUITING
Conditions: Opioid Analgesic Adverse Reaction
Interventions: DRUG: Esketamine, Sulfentanil or/and Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effects of Hip Abductor and External Rotator Strength Training in Patients With Patellofemoral Pain Syndrome
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Additional Hip Muscle Strengthening to Leg Press Exercise|OTHER: Leg Press Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Pioglitazone and Azilsartan in Treating Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Pioglitazone and azilsartan|DRUG: Pioglitazone and azilsartan|DRUG: Pioglitazone|DRUG: Pioglitazone and azilsartan|DRUG: Pioglitazone and azilsartan|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Performance Study of the CAdiscTM-L Lumbar Spinal Disc Replacement Device For CE Marking
Status: COMPLETED
Conditions: Chronic Low Back Pain|Lumbar Degenerative Disc Disease
Interventions: DEVICE: CAdisc™-L (Total Disc Replacement)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Single Centre Randomized Study Evaluating The Safety And Tolerability Of GSK573719 In Healthy Volunteers
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK573719
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 123I-MIBG Scintigraphy in Patients Being Evaluated for Neuroendocrine Tumors
Status: UNKNOWN
Conditions: Pheochromocytoma|Neuroblastoma|Paraganglioma|Medullary Thyroid Carcinoma|Carcinoid Tumors
Interventions: DRUG: 123I-meta-iodobenzylguanidine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Nivolumab, Ixazomib, Cyclophosphamide, and Dexamethasone in Relapsed/Refractory Myeloma
Status: TERMINATED
Conditions: Relapsed Multiple Myeloma|Refractory Multiple Myeloma
Interventions: DRUG: Nivolumab|DRUG: Ixazomib|DRUG: Dexamethasone|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sample Collection Study to Aid Evaluation of an Influenza A/B, Respiratory Syncytial Virus & COVID-19 Virus POC Test
Status: SUSPENDED
Conditions: Covid19|RSV Infection|Influenza Type A|Influenza Type B
Interventions: OTHER: Sample Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Accelerated Transcranial Magnetic Stimulation for People With Schizophrenia Treated With Clozapine
Status: RECRUITING
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DEVICE: sham stimulation|DEVICE: transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Open Label Study Evaluating the Effects of a Single Oritavancin Infusion on Cytochrome P450 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Single-Dose IV Oritavancin Diphosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quit2Heal Smartphone App in Helping Cancer Patients Quit Smoking
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic and Lymphoid System Neoplasm|Malignant Solid Neoplasm
Interventions: BEHAVIORAL: Quit2Heal|BEHAVIORAL: QuitGuide|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Laparoscopic Ovarian Diathermy and Urinary Purified FSH in Women With Clomiphene Citrate Resistant Polycystic Ovarian Syndrome.
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: FSH|PROCEDURE: Laparoscopic ovarian drilling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Multicentre, Dose Finding, Ph II,CP-4055 in Comb. With Sorafenib - Patients With Metastatic Malignant Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DRUG: CP-4055|DRUG: Sorafenib (Nexavar)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Technique in Congenital/Pediatric Cataract Surgery
Status: COMPLETED
Conditions: Pediatric Cataract|Congenital Cataract
Interventions: OTHER: The cataract surgery and the anterior vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Propranolol Hydrochloride and Pembrolizumab in Treating Patients With Stage IIIC-IV Melanoma That Cannot Be Removed by Surgery
Status: RECRUITING
Conditions: Stage IIIC Cutaneous Melanoma AJCC v7|Stage IV Cutaneous Melanoma AJCC v6 and v7
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab|DRUG: Propranolol Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccination With Dendritic Cells Pulsed With Autologous Tumor Homogenate in Combination With HD-IL2 and Immunomodulating Radiotherapy in Metastatic RCC
Status: WITHDRAWN
Conditions: Carcinoma, Renal Cell|Vaccination|Secondary
Interventions: RADIATION: boost radiotherapy (XRT)|BIOLOGICAL: Autologous DC vaccine|DRUG: High-Dose IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In-patient Study With GSK716155 In Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: GSK716155 subcutaneous injections|BIOLOGICAL: placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Searching for Masses and Calcifications at the Same Time in Breast Cancer Screening
Status: RECRUITING
Conditions: Mammography|Breast Cancer|Radiology
Interventions: BEHAVIORAL: Search only for masses|BEHAVIORAL: Search only for calcifications|BEHAVIORAL: Search for both together|BEHAVIORAL: Search for one after the other
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Two Bundles of Care to Reduce Surgical Site Infection in Colorectal Surgery (CCR-VINCat 2)
Status: COMPLETED
Conditions: Colon Cancer|Rectal Cancer|Surgical Site Infection
Interventions: OTHER: Implementation of a bundle of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Interactive Voice Response (IVR) Symptom Assessment in Non-Small Cell Lung Cancer (NSCLC) Patients
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BEHAVIORAL: Questionnaire|BEHAVIORAL: Interactive Voice Response Telephone System|BEHAVIORAL: IVR Plus Triage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vision Improvement for Patients With Age-Related Macular Degeneration
Status: NOT_YET_RECRUITING
Conditions: Age-related Macular Degeneration
Interventions: DEVICE: Optimal Acuity Clear-K® Low Vision Aid System treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing PG286 Ophthalmic Solution, 0.5% Compared to Its Individual Components for 28 Days
Status: COMPLETED
Conditions: Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: PG286 Ophthalmic Solution 0.5%|DRUG: AR-12286 Ophthalmic Solution 0.5%|DRUG: Travoprost Ophthalmic Solution 0.004%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of LYM-X-SORB™ to Improve Fatty Acid and Choline Status in Children With CF and PI
Status: COMPLETED
Conditions: Cystic Fibrosis|Pancreatic Insufficiency
Interventions: DIETARY_SUPPLEMENT: Lym-X-Sorb powder|DIETARY_SUPPLEMENT: Placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Propofolsleep - A Study on Cardiopulmonary and Pharyngeal Reactions While Drug Induced Sleep Endoscopy (DISE)
Status: UNKNOWN
Conditions: Sleep Apnea, Obstructive|Electroencephalography|Echocardiography|Blood Gas Monitoring, Transcutaneous|Consciousness Monitors
Interventions: DEVICE: PSI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Feasibility Study of RapidPulseTM Aspiration System for Patients With Acute Ischemic Stroke
Status: RECRUITING
Conditions: Acute Ischemic Stroke|Stroke|Large Vessel Occlusion|Mechanical Thrombectomy
Interventions: DEVICE: RapidPulseTM Aspiration System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Long-Term Safety and Efficacy of Pregabalin in Patients With Postherpetic Neuralgia.
Status: COMPLETED
Conditions: Neuralgia
Interventions: DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Carboplatin for the Treatment of Participants With Recurrent or Refractory Intraocular Retinoblastoma
Status: COMPLETED
Conditions: Retinoblastoma
Interventions: DRUG: Carboplatin|DRUG: Maxitrol®|PROCEDURE: Focal Therapy|PROCEDURE: Plaque Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Ankle Joint Braces Efficiency
Status: COMPLETED
Conditions: Ankle Injuries|Ankle Sprains
Interventions: OTHER: ankle joint brace 1|OTHER: ankle joint brace 2|OTHER: ankle joint brace 3|OTHER: ankle joint brace 4|OTHER: ankle joint brace 5
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Motor Imagery for Treatment Enhancement and Efficacy in Persons With Apraxia of Speech
Status: RECRUITING
Conditions: Apraxia, Oral|Apraxia of Speech
Interventions: BEHAVIORAL: Sound production treatment|BEHAVIORAL: Motor Imagery Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CD388 Subcutaneous Administration in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: COMBINATION_PRODUCT: CD388 Injection|DRUG: Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High Flow Nasal Oxygen for Children With Cystic Fibrosis Presenting With Respiratory Failure - a Randomized Controlled Study
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DEVICE: Hi-flow nasal cannula|DEVICE: Venturi mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin C for the Prevention of UTI in Women Who Undergo Elective Gynecological Surgeries
Status: WITHDRAWN
Conditions: Catheter-Associated Urinary Tract Infection, Ascorbic Acid
Interventions: DRUG: Ascorbic Acid 1000 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: DNA Analysis of Blood and/or Tissue Samples From Patients With Primary Kidney Cancer Receiving Sorafenib on Clinical Trial MRC-RE05-SORCE
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: GENETIC: mutation analysis|GENETIC: polymorphism analysis|GENETIC: protein expression analysis|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Giardia Induced Fatigue and Functional Gastrointestinal Diseases
Status: COMPLETED
Conditions: Chronic Fatigue Syndrome
Interventions: OTHER: Psycoeducation/counseling|BEHAVIORAL: Cognitive behavioural therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Outcome of Healing Intraoral Sinus Tract With a Single or Multi-visit With Bioceramic Sealer
Status: UNKNOWN
Conditions: Sinus Tract|Singler Visit|Multi Visit|Single Cone Obturation Technique|Bioceramic Sealer
Interventions: PROCEDURE: sinus tract healing in single or multi visit with single cone technique with bioceramic sealer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research Study Investigating How Well Semaglutide Works in People From Thailand and South Korea Living With Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Semaglutide 2.4 mg|DRUG: Placebo (semaglutide 2.4 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Low-Flow Anesthesia on Hemodynamic Parameters and Oxygenation in Morbidly Obese Patients
Status: COMPLETED
Conditions: Morbid Obesity|Hemodynamic Instability|Bariatric Surgery Candidate
Interventions: DIAGNOSTIC_TEST: hemodynamic parameters|DIAGNOSTIC_TEST: arterial blood gase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Treatment of Philadelphia-Positive Acute Lymphocytic Leukemia (Ph+ ALL) in the Elderly With Imatinib Mesylate (STI571) and Chemotherapy.
Status: UNKNOWN
Conditions: Acute Lymphocytic Leukemia
Interventions: DRUG: imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Ficlatuzumab w/wo Cetuximab in Patients w/Cetuximab-Resistant, Recurrent or Metastatic Head/Neck Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Head and Neck Basaloid Carcinoma|Recurrent Head and Neck Squamous Cell Carcinoma|Recurrent Oropharyngeal Squamous Cell Carcinoma|Squamous Cell Carcinoma of Unknown Primary Origin|Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IV Nasopharyngeal Keratinizing Squamous Cell Carcinoma|Stage IV Oropharyngeal Squamous Cell Carcinoma|Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma|Stage IVA Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma|Stage IVA Nasopharyngeal Keratinizing Squamous Cell Carcinoma|Stage IVA Oropharyngeal Squamous Cell Carcinoma|Stage IVB Lip and Oral Cavity Squamous Cell Carcinoma|Stage IVB Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma|Stage IVB Nasopharyngeal Keratinizing Squamous Cell Carcinoma|Stage IVB Oropharyngeal Squamous Cell Carcinoma|Stage IVC Lip and Oral Cavity Squamous Cell Carcinoma|Stage IVC Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma|Stage IVC Nasopharyngeal Keratinizing Squamous Cell Carcinoma|Stage IVC Oropharyngeal Squamous Cell Carcinoma|Head and Neck Cancer|Oropharyngeal Cancer|HNSCC|Stage IV Lip and Oral Cavity Squamous Cell Carcinoma
Interventions: BIOLOGICAL: Cetuximab|DRUG: Ficlatuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Term Effects of Synchronized vs. Non-synchronized NIPPV in Preterm Infants.
Status: RECRUITING
Conditions: Newborn Respiratory Distress|Preterm Infant
Interventions: DEVICE: NIPPV|DEVICE: SNIPPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immune Non-Inferiority, Safety and Lot-to-Lot Consistency of Oral Cholera Vaccine-Simplified Compared to Shanchol™
Status: COMPLETED
Conditions: Cholera
Interventions: BIOLOGICAL: Oral Cholera Vaccine Simplified (OCV-S)|BIOLOGICAL: Shanchol™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sequences Of REGorafenib And Trifluridine/Tipiracil in Patients With Metastatic Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Regorafenib then Trifluridine/Tipiracil|DRUG: Trifluridine/Tipiracil then Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Companion Study for Studies THAL-MM-003, CC-5013-MM-009, and CC-5013-MM-010 for Subjects With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: CC-5013|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of an Amino Acid Blend on Muscle and Gut Functionality in ICU Patients
Status: COMPLETED
Conditions: Enteral Nutrition
Interventions: DIETARY_SUPPLEMENT: Blend of amino acids|DIETARY_SUPPLEMENT: Maltodextrin only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pain and Anxiety Reducing During Dental Treatment in Children Using Video Game on Tablet Device With Joystick.
Status: COMPLETED
Conditions: Pulpotomy|Dental Caries|Primary Teeth
Interventions: BEHAVIORAL: Evaluation of the effectiveness of Video Game Distraction in the management of anxious pediatric patients during dental treatment|BEHAVIORAL: Evaluation of the effectiveness of Audio Video Distraction in the management of anxious pediatric patients during dental treatment|OTHER: Evaluation of the anxiety in pediatric patients during dental treatment without using any type of distraction aids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exemestane Compared With Tamoxifen in Treating Postmenopausal Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: exemestane|DRUG: tamoxifen citrate|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI-Guided Radiation Therapy for the Treatment of Early-Stage Kidney Cancer, the MRI-MARK Trial
Status: WITHDRAWN
Conditions: Renal Cell Carcinoma|Stage I Renal Cell Cancer AJCC v8|Stage II Renal Cell Cancer AJCC v8
Interventions: PROCEDURE: Magnetic Resonance Imaging|OTHER: Questionnaire Administration|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of BBIBP-Corv Coadministered With PPV23 and IIV4 in Hemodialysis Population
Status: UNKNOWN
Conditions: Hemolysis|COVID-19
Interventions: BIOLOGICAL: coadministration|BIOLOGICAL: COVID-19 vaccine|BIOLOGICAL: IIV4+PPV23
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: IntuBrite Versus Macintosh for Endotracheal Intubation in Out of Hospital Cardiac Arrest
Status: COMPLETED
Conditions: Intubation Complication|Cardiopulmonary Arrest
Interventions: DEVICE: IntuBrite intubation|DEVICE: Macintosh laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treatment of Mycobacterium Xenopi Pulmonary Infection
Status: COMPLETED
Conditions: Atypical; Mycobacterium, Pulmonary, Tuberculous
Interventions: DRUG: Clarithromycin|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 1st or 2nd Line MBC (Metastatic Breast Cancer) With Previous Avastin (Bevacizumab) Therapy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Gemcitabine|DRUG: Sorafenib|DRUG: Placebo|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Combined Neuromodulation Therapy to Enhance Balance and Neuroplasticity
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries|Muscle Pareses|Fall
Interventions: OTHER: Activity-based rehabilitation+electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omacor for the Treatment of Vascular Dysfunction in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Atherosclerosis|Type 2 Diabetes Mellitus
Interventions: DRUG: Omacor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: In Line Aerosol Nebulization With High Flow
Status: RECRUITING
Conditions: Hypoxemic Respiratory Failure|Airway Obstruction
Interventions: DEVICE: nebulizer via in-line drug delivery maintaining high-flow nasal cannula oxygen|DEVICE: standard jet nebulization (SJN) with face mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Regional Lung Mechanics in Obese Patients Undergoing Laparoscopic Surgery
Status: UNKNOWN
Conditions: Obesity|Mechanical Ventilation Pressure High|Intraoperative Respiratory Injury
Interventions: PROCEDURE: PEEP titration trial
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Low Dose MM-120 for ADHD Proof of Concept Trial
Status: COMPLETED
Conditions: ADHD|Attention Deficit Disorder
Interventions: DRUG: MM-120|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Behavior Intervention for Weight Loss for Type 2 Diabetes Mellitus Adults With Obesity Problem (BMI of ≥23kg/m2)
Status: COMPLETED
Conditions: Obesity|Diabetes Mellitus, Type 2|Behavior
Interventions: BEHAVIORAL: Chance2Act
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 1b Influenza Vaccine Study in Healthy Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza vaccine (FLU-v)|BIOLOGICAL: FLU-v Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oral Nitrite and Nitrate in Healthy Normal Volunteer Adults
Status: COMPLETED
Conditions: Focus of Study of Healthy Adults
Interventions: DRUG: 15Nitrogen(15N)-labeled sodium nitrite|DRUG: 15Nitrogen(15N)-labeled sodium nitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Corticosteroids vs Placebo on Duration of Ventilatory Support During Severe Acute Exacerbations of COPD Patients in the ICU
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Methylprednisolone|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Decreasing Radiation Therapy and Chemotherapy in People With Head and Neck Cancer
Status: RECRUITING
Conditions: Head and Neck Cancer|Head and Neck Carcinoma|Head and Neck Neoplasms|Head and Neck Squamous Cell Carcinoma
Interventions: DIAGNOSTIC_TEST: 18F-FMISO PET/CT scan|RADIATION: Chemoradiation therapy|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of a Fluocinolone Acetonide Intravitreal Insert (FA-i) to Treat Intermediate-, Posterior-, or Panuveitis
Status: COMPLETED
Conditions: Uveitis Affecting the Posterior Segment
Interventions: DRUG: Fluocinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Epirubicin (Pharmorubicin®), Carboplatin (Paraplatin®) and Capecitabine (Xeloda®) (ECC) in the Treatment of Unresectable Locally Advanced or Metastatic Gastric/Gastroesophageal Junction Cancer With Pharmacogenetic Correlates
Status: TERMINATED
Conditions: Gastric Cancer|Esophageal Cancer|Tumors
Interventions: DRUG: Epirubicin|DRUG: Carboplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Web Application to Reduce Heavy Drinking in First-time DWI Offenders
Status: COMPLETED
Conditions: Driving While Intoxicated|Driving Under the Influence|Heavy Drinking|Alcohol Abstinence
Interventions: BEHAVIORAL: Right Turns web application|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ramelteon on Speeding Up Sleep in Subjects With Delayed Sleep Phase Syndrome
Status: COMPLETED
Conditions: Sleep Disorders, Circadian Rhythm
Interventions: DRUG: Ramelteon|DRUG: Ramelteon|DRUG: Ramelteon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity to Human Papillomavirus Vaccine (Gardasil) Among IBD Patients on Immunosuppressive Therapy
Status: COMPLETED
Conditions: Inflammatory Bowel Disease
Interventions: BIOLOGICAL: Gardasil vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Improving Obesity Self-Care Among Mentally Ill Veterans
Status: COMPLETED
Conditions: Anxiety|Depression|PTSD|Obesity
Interventions: BEHAVIORAL: MH MOVE|BEHAVIORAL: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ribociclib (LEE011) in Preoperative Glioma and Meningioma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma Multiforme|Meningioma
Interventions: DRUG: Ribociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The COPE Study: Pilot Intervention to Improve Symptom Self-management and Coping in Adults With Post COVID-19
Status: COMPLETED
Conditions: Post COVID-19 Condition|Post-COVID-19 Syndrome
Interventions: BEHAVIORAL: 6-Week Self-Management Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomised Evaluation of COVID-19 Therapy
Status: RECRUITING
Conditions: Severe Acute Respiratory Syndrome
Interventions: DRUG: Lopinavir-Ritonavir|DRUG: Corticosteroid|DRUG: Hydroxychloroquine|DRUG: Azithromycin|BIOLOGICAL: Convalescent plasma|DRUG: Tocilizumab|BIOLOGICAL: Immunoglobulin|DRUG: Synthetic neutralising antibodies|DRUG: Aspirin|DRUG: Colchicine|DRUG: Baricitinib|DRUG: Anakinra|DRUG: Dimethyl fumarate|DRUG: High Dose Corticosteroid|DRUG: Empagliflozin|DRUG: Sotrovimab|DRUG: Molnupiravir|DRUG: Paxlovid|DRUG: Baloxavir Marboxil|DRUG: Oseltamivir|DRUG: Low-dose corticosteroids: Dexamethasone|DRUG: Low-dose corticosteroids: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Perampanel Tablets 10 mg
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Perampanel 10 MG|DRUG: Fycompa 10Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Ciclesonide Administered With or Without Different Spacers in Patients With Asthma (12 to 75 y) (BY9010/M1-145)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Ciclesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3022855 In Participants With Breast or Prostate Cancer
Status: COMPLETED
Conditions: Neoplasms|Neoplasm Metastasis
Interventions: DRUG: LY3022855
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: This Study Collects Information on the Safety of Inhaled Pegylated Adrenomedullin (PEG-ADM), How the Drug is Tolerated and How it Affects Patients Suffering From a Type of Lung Failure That Cause Fluid to Build up in the Lungs Making Breathing Difficult (ARDS)
Status: TERMINATED
Conditions: Acute Respiratory Distress Syndrome
Interventions: DRUG: BAY1097761 Active Dose 1|OTHER: Placebo to BAY1097761|DRUG: BAY1097761 Active Dose 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CES in the Elderly With Generalized Anxiety Disorders
Status: TERMINATED
Conditions: CES|Anxiety Disorders and Symptoms
Interventions: DEVICE: CES, Alpha-Stim stimulator (Electromedical Products International, Inc., Mineral Wells, Texas, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dachaihu Decoction Compound and Rhubarb Single Medicine in the Treatment of Acute Pancreatitis
Status: NOT_YET_RECRUITING
Conditions: Acute Pancreatitis
Interventions: COMBINATION_PRODUCT: Dachaihu decoction compound|DRUG: Rhubarb single medicine|COMBINATION_PRODUCT: Regular therapies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Detection of Infection Using the Fitbit in Pediatric Surgical Patients
Status: NOT_YET_RECRUITING
Conditions: Appendectomy|Appendicitis|Appendicitis Acute
Interventions: DEVICE: Infection-Prediction Algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Yoga Improves Aerobic Fitness, Glycemia and Mood State and Reduces Abdominal Obesity
Status: COMPLETED
Conditions: Obesity|Insulin Resistance
Interventions: OTHER: Protein whole foods|OTHER: Protein Resistance Exercise Training|OTHER: Protein Stretching/Yoga Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Readiness for Behavior Change After a Heart Attack
Status: COMPLETED
Conditions: Myocardial Infarction|Stable Angina|Coronary Artery Disease
Interventions: BEHAVIORAL: Early appointment (within 10 days)|OTHER: Routine referral (at 5 weeks)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Study on the Second-line and Above Treatment of Advanced Solid Tumor With Anlotinib Combined With Pd-1 Antibody
Status: UNKNOWN
Conditions: Advanced Solid Tumor
Interventions: DRUG: Anlotinib|DRUG: pd-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pivotal Study of Safety and Effectiveness of NanoKnife IRE for Stage 3 Pancreatic Cancer
Status: RECRUITING
Conditions: Stage III Pancreatic Cancer
Interventions: DRUG: Modified FOLFIRINOX Regimen|DEVICE: NanoKnife System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The ReNEW Study: Maestro® New Enrollment Post-Approval Study Protocol
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity, Morbid
Interventions: DEVICE: vBloc Maestro Rechargeable System|OTHER: vBloc Achieve Weight Management Program|OTHER: Control Weight Management (CWM) program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Colors, Can They Reduce the Dental Anxiety
Status: RECRUITING
Conditions: Anxiety|Anxiety State|Tooth Extraction Status Nos
Interventions: OTHER: Green color exposure|OTHER: Red color exposure|OTHER: Blue color exposure|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab, Erlotinib and 5-Fluorouracil With External Beam Radiation Therapy in Locally Advanced Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer|Adenocarcinoma of the Rectum
Interventions: DRUG: 5-fluorouracil|DRUG: bevacizumab|DRUG: erlotinib|PROCEDURE: External beam radiation therapy (EBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ranolazine for Diabetic Peripheral Neuropathic Pain (DPNP)
Status: TERMINATED
Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: DRUG: Ranolazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Immunogenicity of COVID-19 Vaccine in Children 6 Months to < 12 Years
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: Biological/Vaccine: SARS-CoV-2 rS/Matrix-M1 Adjuvant (Initial Vaccination Period)|BIOLOGICAL: SARS-CoV-2 rS/Matrix-M1 Adjuvant (Open Label Crossover Vaccination period)|BIOLOGICAL: SARS-CoV-2 rS/Matrix-M1 Adjuvant (Booster Vaccination)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate Intravenous Tocilizumab in Participants With Moderate to Severe COVID-19 Pneumonia
Status: COMPLETED
Conditions: COVID-19 Pneumonia
Interventions: DRUG: Tociliuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Structural and Myelin Abnormalities on Cognitive Impairments in Recent-onset Schizophrenia - Before and After Lurasidone Treatment (MARYLU)
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: Lurasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Glycemic Responses to Majia Pomelos in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Diabetes
Interventions: DIETARY_SUPPLEMENT: Pomelo|DIETARY_SUPPLEMENT: Glucose|OTHER: Blank|DRUG: Insulin|DRUG: met or diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: GLUCOSAMINE/CHONDROITIN and PHYSICAL THERAPY EFFECTS ON OLDER POPULATION WITH KNEE OSTEOARTHRITIS
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Glucosamine Chondroitin|COMBINATION_PRODUCT: glucosamine chondritin & Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Examine the Pharmacodynamics of Different AZD1722 Formulations
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD1722|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Contrast Enhanced Ultrasound Compared to MRI for Differentiation of Hepatic Lesions
Status: COMPLETED
Conditions: Hepatic Disease
Interventions: DRUG: Sulfur Hexafluoride Microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of PLX73086 in Advanced Solid Tumors and Locally Advanced or Refractory Tenosynovial Giant Cell Tumor
Status: TERMINATED
Conditions: Solid Tumors|Tenosynovial Giant Cell Tumor|Synovitis, Pigmented Villonodular
Interventions: DRUG: PLX73086
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT