pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Research Study Comparing a New Medicine Semaglutide to Liraglutide in People With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: Semaglutide|DRUG: Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tenofovir Alafenamide Switching Therapy in Kidney or Liver Transplant Recipients With Chronic HBV Infection
Status: RECRUITING
Conditions: Safety Issues
Interventions: DRUG: Tenofovir Alafenamide 25 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CC-4047 and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma or Amyloidosis
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: dexamethasone|DRUG: pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LV Only MPP With SyncAV
Status: COMPLETED
Conditions: Heart Failure|Left Bundle-Branch Block
Interventions: DEVICE: BiV pacing with MPP and SyncAV|DEVICE: LV only pacing with MPP and SyncAV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Japanese Study of Rimonabant in Obese Patients With Dyslipidemia (VENUS)
Status: TERMINATED
Conditions: Obesity
Interventions: DRUG: rimonabant (SR141716)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Baricitinib (LY3009104) in Patients With Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Baricitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carbon-Fibre Accessory (CARA) for Supine Breast Positioning to Reduce Toxicity in Whole Breast Radiotherapy
Status: RECRUITING
Conditions: Adjuvant Radiotherapy for Breast Cancer
Interventions: DEVICE: Carbon-Fibre Adjustable Reuseable Accessory (CARA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Exogenous Ketosis During Bed Rest in Older Adults
Status: COMPLETED
Conditions: Muscle Protein Synthesis|Muscle Atrophy|Insulin Sensitivity|Mitochondrial Function|Physical Inactivity|Cognitive Function|Muscle Strength|Functional Capacity
Interventions: DIETARY_SUPPLEMENT: ketone monoester (R)-3-hydroxybutyl (R)-3- hydroxybutyrate|DIETARY_SUPPLEMENT: carbohydrate-fat placebo (fructose, corn and canola oil 50:50 ratio)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CT and MRI in Prediction of Response in Patients With Gastric Cancer Following Neoadjuvant Chemotherapy and/or Immunotherapy
Status: UNKNOWN
Conditions: Gastric Cancer|Magnetic Resonance Imaging|Tomography, X-Ray Computed|Neoadjuvant Immunotherapy|Neoadjuvant Chemotherapy
Interventions: DRUG: PD-1 inhibitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Collagenase in the Treatment of Adhesive Capsulitis (Frozen Shoulder)
Status: WITHDRAWN
Conditions: Adhesive Capsulitis|Frozen Shoulder
Interventions: DRUG: Collagenase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Nitroglycerin to Facilitate Trans-radial Access.
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Nitroglycerin 100 MCG/ML Injectable Solution|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Monoclonal Antibody in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: lumiliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of CoQ10 Administration on Hemodialysis Patients
Status: COMPLETED
Conditions: Chronic Renal Failure|Hemodialysis
Interventions: DRUG: Coenzyme Q10 (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EoE RCT Fluticasone and Omeprazole vs Fluticasone Alone
Status: UNKNOWN
Conditions: Eosinophilic Esophagitis
Interventions: DIAGNOSTIC_TEST: Retrospective evaluation of endoscopy prior to study drug|OTHER: Symptom Survey|OTHER: Medication Compliance Phone Call|DIAGNOSTIC_TEST: Endoscopy while on study drug|OTHER: Symptom Survey|DRUG: Fluticasone|DRUG: Omeprazole|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pharmacokinetics and Safety/Tolerability Profiles of DA-5206 Versus Talion® Under Fasting and Fed States in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DA-5206(Fasting)|DRUG: DA-5206(Fed)|DRUG: TALION®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transnasal Endoscopic Pituitary Surgery - the Effect of Posterior Nasal Septum Resection on Nasal Functions
Status: COMPLETED
Conditions: Pituitary Adenoma
Interventions: PROCEDURE: Posterium nasal septum resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Experimental Anti-cancer Drug SLC-391 With an Approved Immunotherapy Drug, Pembrolizumab, for Advanced Lung Cancers
Status: RECRUITING
Conditions: Lung Cancer, Nonsmall Cell|Lung Cancer Stage IV|Lung Cancer Metastatic
Interventions: DRUG: SLC-391|BIOLOGICAL: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Dose Finding Study of CC-90002 in Subjects With Advanced Solid and Hematologic Cancers
Status: COMPLETED
Conditions: Hematologic Neoplasms
Interventions: DRUG: CC-90002|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nabilone for Non-motor Symptoms in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Nabilone 0.25 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Pilot Study of Multimodal Radiological Evaluation Feasibility During Chemoradiotherapy of Rectal Adenocarcinomas
Status: TERMINATED
Conditions: Rectal Adenocarcinoma
Interventions: PROCEDURE: Pelvic MRI and F MISO TEP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Repair of Soft Tissue Defect of the Finger Using the Heterodigital Neurocutaneous Island Flap
Status: COMPLETED
Conditions: Sensory Reconstruction of the Volar Aspect of the Finger|The Heterodigital Neurocutaneous Island Flap
Interventions: DEVICE: the neurocutaneous island flap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The SOLACE-AU Clinical Trial
Status: COMPLETED
Conditions: Severe, Symptomatic Aortic Stenosis
Interventions: DEVICE: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Dose-proportionality and Effects of FG-4592 in Healthy Young and Elderly Male and Female Subjects
Status: COMPLETED
Conditions: PK for FG-4592|Healthy Subjects
Interventions: DRUG: FG-4592|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Building Adherence to Live With And Navigate my Cystic Fibrosis (CF) Experience
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: BEHAVIORAL: Motivational Interviewing|OTHER: Cystic Fibrosis Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Comparison Between NCRT and NCT Followed by MIE for Treatment of Locally Advanced Resectable ESCC
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma Stage cT3-4aN0-1M0
Interventions: PROCEDURE: Neoadjuvant Chemoradiotherapy|PROCEDURE: Neoadjuvant Chemotherapy|PROCEDURE: Minimally Invasive Esophagectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics Supplementation on the Side Effects of Radiation Therapy Among Colorectal Cancer Patients
Status: WITHDRAWN
Conditions: Colorectal Cancer
Interventions: DIETARY_SUPPLEMENT: Probiotic Formula Capsule|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immune Equivalence Between Multi-dose and Single Dose Formulation of Vi-DT and Their Overall Safety (Phase III)
Status: COMPLETED
Conditions: Typhoid
Interventions: BIOLOGICAL: Vi-DT (Multi-dose formulation)|BIOLOGICAL: Vi-DT (Single dose formulation)|BIOLOGICAL: Control Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Virtual Reality in COPD Exacerbation
Status: RECRUITING
Conditions: COPD Exacerbation|Pulmonary Rehabilitation
Interventions: DEVICE: virtual reality|OTHER: conventional pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of Ambroxol Hydrochloride Lozenge in Comparison to Ambroxol Hydrochloride Syrup (Mucosolvan®) in Healthy Female and Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ambroxol hydrochloride - lozenge|DRUG: Ambroxol hydrochloride - syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strategy Based Technique to Enhance Memory (STEM) for Improving New Learning and Memory (NLM) in Moderate to Severe TBI
Status: RECRUITING
Conditions: Traumatic Brain Injury|Cognitive Impairment
Interventions: BEHAVIORAL: SME
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioactive Restorative vs GIC Modified Glass Ionomer in Restoration of Cervical Lesions: Randomized Controlled Trial
Status: UNKNOWN
Conditions: Clinical Performance Using Modified USPHS Criteria
Interventions: OTHER: New Bioactive Restorative Material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn More About How Well Elinzanetant Works and How Safe it is Compared to Placebo for the Treatment of Hot Flashes Caused by Anti-cancer Therapy in Women With, or at High Risk for Developing Hormone-receptor Positive Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Vasomotor Symptoms Caused by Adjuvant Endocrine Therapy in Women With, or at High Risk for Developing Hormone-receptor Positive Breast Cancer|Hot Flashes
Interventions: DRUG: Elinzanetant (BAY3427080)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Stimulation-aided Stroke Rehabilitation: Neural Mechanisms of Recovery
Status: COMPLETED
Conditions: Stroke
Interventions: PROCEDURE: tDCS: noninvasive brain stimulation|BEHAVIORAL: Constraint induced movement therapy (CIMT)|PROCEDURE: Sham tDCS: placebo noninvasive brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Validation of a Cardiovascular Autonomic Nervous Function Multi-Parameter Evaluation System
Status: COMPLETED
Conditions: Cardiovascular Autonomic Neuropathy
Interventions: DEVICE: Cardiovascular Autonomic Nervous Function Multi-Parameter Evaluation System (Model: R6000)|DIAGNOSTIC_TEST: Conventional method of CARTs|DEVICE: Ambulatory holter station Model i12 plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Hectorol in Pediatric Patients With Chronic Kidney Disease Stage 3 and 4 With Secondary Hyperparathyroidism Not Yet on Dialysis
Status: ACTIVE_NOT_RECRUITING
Conditions: Secondary Hyperparathyroidism-Chronic Kidney Disease
Interventions: DRUG: Doxercalciferol (GZ427397)|DRUG: Calcitriol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CSP594 Comparative Effectiveness in Gout: Allopurinol vs. Febuxostat
Status: COMPLETED
Conditions: Gout|Chronic Kidney Diseases
Interventions: DRUG: allopurinol capsule, 100-800 mg by mouth once daily|DRUG: febuxostat tablet 40-120 mg by mouth once daily|DRUG: Placebo, vehicle control (febuxostat-shaped)|DRUG: Placebo, vehicle control (allopurinol-shaped)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dimensional Changes in Alveolar Ridge Preservation
Status: RECRUITING
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: Control group|PROCEDURE: Mixed free gingival graft group|PROCEDURE: Bone+ mixed free gingival graft group|PROCEDURE: Bone + Titanium Seal group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Vitamin D on Inflammatory Bowel Disease Remission
Status: UNKNOWN
Conditions: Inflammatory Bowel Disease
Interventions: DIETARY_SUPPLEMENT: Vitamin D|OTHER: Water or milk|DIETARY_SUPPLEMENT: Vitamin D enriched milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of PROVIGIL ® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Narcolepsy
Status: COMPLETED
Conditions: Narcolepsy
Interventions: DRUG: Modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Chinese Herbal Therapy for Asthma
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: ASHMI 4|DRUG: ASHMI 12|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Pharmacokinetics of MK-8242 in Participants With Advanced Solid Tumors (P07650)
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: MK-8242
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Preliminary Effect of TEVAW: a Program to Address Intimate Partner Violence in Northern Tanzania
Status: COMPLETED
Conditions: Intimate Partner Violence
Interventions: BEHAVIORAL: Male Peer Groups|BEHAVIORAL: Male Peer Groups and Community Dialogues
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Robotic Assisted Early Mobilization in Ventilated ICU Patients
Status: COMPLETED
Conditions: Critical Illness Polyneuromyopathy|Critical Illness|Early Ambulation|Rehabilitation
Interventions: DEVICE: Robotic-assisted early mobilization|OTHER: Early mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The StoneBreakerTM Trial
Status: COMPLETED
Conditions: Percutaneous Nephrolithotripsy
Interventions: DEVICE: The stonebreaker arm (LMA Stonebreaker)|DEVICE: Pneumatic Lithotripsy (Swiss LithoClastR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Food Aid Quality Review: Feasibility and Acceptability Study of Corn Soy Blend and Fortified Vegetable Oil in Malawi
Status: COMPLETED
Conditions: Child Malnutrition
Interventions: BEHAVIORAL: Receive extra oil|BEHAVIORAL: Receives behavior changed messages on CSB package
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Gambia Pertussis Study (GaPs)
Status: UNKNOWN
Conditions: Pertussis
Interventions: BIOLOGICAL: Boostrix IPV infant acellular Pertussis|BIOLOGICAL: Boostrix IPV infant whole Pertussis|BIOLOGICAL: TT infant acellular Pertussis|BIOLOGICAL: TT infant whole Pertussis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adjuvant Treatment for High-risk Triple Negative Breast Cancer Patients With the Anti-PD-l1 Antibody Avelumab
Status: ACTIVE_NOT_RECRUITING
Conditions: Triple Negative Breast Neoplasms
Interventions: DRUG: MSB0010718C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of Acyclovir Among HIV and HSV-2 Co-Infected Women, Chiang Rai, Thailand
Status: COMPLETED
Conditions: HIV|Herpes
Interventions: DRUG: acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Preventive Dendritic Cell Vaccine, AV-COVID-19, in Subjects Not Actively Infected With COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: AV-COVID-19
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Discharge Training and Telephone Counseling
Status: COMPLETED
Conditions: Discharge Training and Telephone Counseling for Coronary Artery Bypass Graft Patients
Interventions: BEHAVIORAL: Telephone Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Inspiratory Muscle Training in COPD
Status: COMPLETED
Conditions: COPD|Inspiratory Muscle Weakness
Interventions: PROCEDURE: Inspiratory Muscle Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RCT Comparing Immunosuppressive Regimens in Elderly Renal Transplant Recipients
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Transplant Recipients|Elderly Patients|Immunosuppression
Interventions: DRUG: low dose tacrolimus in combination with everolimus|DRUG: standard dose tacrolimus with mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Polysomnography for Non-Invasive Ventilation Settings' Optimization
Status: UNKNOWN
Conditions: Obesity-Hypoventilation Syndrome (OHS)
Interventions: DEVICE: GoodKnight 425ST - Mallinckrodt DF, Tyco Healthcare
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Weight Management Intervention for Overweight Chinese Cancer Survivors
Status: NOT_YET_RECRUITING
Conditions: Cancer|Weight Loss|Overweight and Obesity
Interventions: BEHAVIORAL: L4 weight management intervention|BEHAVIORAL: Active control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Alendronate Sodium Tablets (10 mg) and Fosamax Tablets (10 mg)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Alendronate Sodium Tablets, 10 mg|DRUG: Fosamax Tablets, 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Laparoscopic Inguinal and Femoral heRniA rePaIr Using Pre-shapeD 4DMESH® (4DLap)
Status: RECRUITING
Conditions: Inguinal Hernia|Femoral Hernia
Interventions: DEVICE: Pre-shaped 4DMESH®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peritoneal Nebulization of Ropivacaine for Pain Control After Laparoscopic Colectomy
Status: TERMINATED
Conditions: Postoperative Pain
Interventions: DRUG: Ropivacaine 150 mg|DRUG: saline 15 ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Investigate PK and PD of CJ-12420, Clarithromycin, Amoxicillin After Multiple Dose Administration
Status: COMPLETED
Conditions: Drug Interaction|Pharmacokinetic|Pharmacodynamic
Interventions: DRUG: CLR 500mg|DRUG: CJ-12420 100mg|DRUG: CJ-12420 50mg|DRUG: AMX 1g|DRUG: Pantoprazole 40mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pilot Study of the Impact of Vitamin D3 on Muscle Performance in Elderly Women
Status: COMPLETED
Conditions: Sarcopenia|Falls
Interventions: DIETARY_SUPPLEMENT: vitamin D3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Placebo Controlled Trial of IVIg in Glycine Receptor Antibody Positive Stiff-person Syndrome
Status: WITHDRAWN
Conditions: Stiff-Person Syndrome
Interventions: DRUG: Intravenous Immunoglobulins, Human|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Swallowing and Breathing Exercises for Dysphagia in Parkinson Disease
Status: COMPLETED
Conditions: Parkinson Disease|Dysphagia
Interventions: OTHER: Swallowing exercise|OTHER: Breathing Exercises|OTHER: Swallowing and breathing exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Atezolizumab in Combination With Cobimetinib in Participants With Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Atezolizumab|DRUG: Cobimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Relative Bioavailability and Food Effect of a New Tablet Formulation and Strength of Suzetrigine
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Suzetrigine|DRUG: Suzetrigine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Responses in Congestive Heart Failure With Cheyne- Stokes Respiration
Status: COMPLETED
Conditions: Heart Failure, Congestive|Cheyne-Stokes Respiration
Interventions: PROCEDURE: Experimental lung function test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial Comparing the Two High-dose Chemotherapies BeEAM and BEAM Given Before Autologous Stem Cell Transplantation (ASCT) in Lymphoma Patients (BEB-trial)
Status: COMPLETED
Conditions: Lymphoma, Large B-Cell, Diffuse|Lymphoma, Follicular|Lymphoma, Mantle-Cell
Interventions: DRUG: BeEAM|DRUG: BEAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Nightly Dexmedetomidine Improve Sleep and Reduce Delirium in ICU Patients?
Status: COMPLETED
Conditions: Sleep Deprivation|Delirium
Interventions: DRUG: Dexmedetomidine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Minimally Invasive Treatment of Worn Dentition With Innovative CAD-CAM Composites
Status: UNKNOWN
Conditions: Tooth Wear
Interventions: DEVICE: "No prep" treatment of worn dentition with CAD-CAM composite
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Early Use of Norepinephrine in Major Abdominal Surgery on Postoperative Organ Dysfunction
Status: RECRUITING
Conditions: Norepinephrine|Hypotension|Anesthesiology|Major Abdominal Surgery
Interventions: DRUG: Ephedrine|DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Visualizing Beta Cells in Patients With a History of Gestational Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Gestational Diabetes
Interventions: RADIATION: 68Ga-NODAGA-exendin-4 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multicenter Trial Comparing Induction C/T Followed by CCRT v.s. CCRT Alone in Stage IV Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: RADIATION: CCRT|DRUG: Mitomycin C,Epirubicin,Cisplatin,5-Fluorouracil,Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells
Status: NOT_YET_RECRUITING
Conditions: Hepatoblastoma|Hepatocellular Carcinoma|Wilms Tumor|Malignant Rhabdoid Tumor|Yolk Sac Tumor|Rhabdomyosarcoma|Liposarcoma|Embryonal Sarcoma of Liver
Interventions: GENETIC: 21.15.GPC3-CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of LHC165 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: LHC165|BIOLOGICAL: PDR001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide and Vaccine Therapy in Treating Patients With Early-Stage Asymptomatic Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Ann Arbor Stage I Small Lymphocytic Lymphoma|Ann Arbor Stage II Small Lymphocytic Lymphoma|Chronic Lymphocytic Leukemia|Chronic Lymphocytic Leukemia With Unmutated Immunoglobulin Heavy Chain Variable-Region Gene|Small Lymphocytic Lymphoma|Small Lymphocytic Lymphoma With Unmutated Immunoglobulin Heavy Chain Variable-Region Gene|Stage 0 Chronic Lymphocytic Leukemia|Stage I Chronic Lymphocytic Leukemia|Stage II Chronic Lymphocytic Leukemia
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|DRUG: Lenalidomide|BIOLOGICAL: Pneumococcal Polyvalent Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Transcutaneous Occipital Nerve Stimulation and Instrument-Assisted Soft Tissue Mobilization on Patients With Chronic Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: OTHER: IASTM|OTHER: home exercise|DEVICE: Chattanooga direct Tens device (DJO UK Ltd, Guildford Surrey, United Kingdom)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Association of Red Blood Cell Transfusion, Anemia, and Necrotizing Enterocolitis
Status: WITHDRAWN
Conditions: Necrotizing Enterocolitis|Anemia|Red Blood Cell (RBC) Transfusion
Interventions: OTHER: RBC transfusion|OTHER: no-RBC transfusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: STUDY OF PF-06882961 IN PARTICIPANTS WITH AND WITHOUT VARYING DEGREES OF HEPATIC IMPAIREMENT
Status: COMPLETED
Conditions: Hepatic Impairment|Healthy Volunteers
Interventions: DRUG: PF-06882961 20MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diagnosis of Tuberculosis Infection in Health Care Workers Using Ex-vivo Interferon-gamma Assay
Status: COMPLETED
Conditions: Latent Tuberculosis Infection
Interventions: OTHER: 1-step tuberculin skin test (TST) and blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Amyloidosis|Amyloid|Amyloid Neuropathies, Familial|Amyloid Cardiomyopathy|Amyloid - Primary|Transthyretin Amyloidosis|AL Amyloidosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optimizing Iron Status While Minimizing Morbidity in HIV-infected Ugandan Children
Status: COMPLETED
Conditions: Anemia|Iron-deficiency|Iron Deficiency Anemia|Hiv
Interventions: DIETARY_SUPPLEMENT: Ferrous Sulfate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D to Improve Glucose Metabolism and Reduce Inflammation in Obese Adolescents
Status: COMPLETED
Conditions: Obesity|Glucose Intolerance|Inflammation
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Vitamin D 3 cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Group Cognitive-behavioral Intervention for Social Anxiety in Schizophrenia
Status: COMPLETED
Conditions: Social Anxiety|Schizophrenia
Interventions: BEHAVIORAL: Cognitive-Behavioral Therapy based intervention immediately|BEHAVIORAL: Wait list
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Acidosis in Renal Transplant Patients
Status: COMPLETED
Conditions: Renal Transplant Patients|Metabolic Acidosis|Physical Capacity|Bone Disease|Mineral Metabolism
Interventions: DRUG: Potassium citrate|DRUG: Potassium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Autologous Stem Cell Transplantation for Patients With Recurrent Nasopharyngeal Carcinoma
Status: TERMINATED
Conditions: Recurrent Nasopharynx Carcinoma
Interventions: DRUG: Etoposide phosphate|DRUG: Carboplatin|DRUG: Ifosfamide|PROCEDURE: Autologous Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the ReX-C System, in Patients Receiving CFTR Modulators for the Treatment of Cystic Fibrosis (CF).
Status: UNKNOWN
Conditions: Cystic Fibrosis|Adherence, Medication
Interventions: DEVICE: ReX-C system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Combination of Glimepiride/Vildagliptin/Metformin in Patients With T2D and Dual Treatment Failure
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: A1=Glimepiride / Vildagliptin / Metformin (1 mg/ 50 mg/ 500 mg)|DRUG: B2=Glimepiride / Vildagliptin / Metformin (1 mg/ 50 mg/ 500 mg)|DRUG: (A2) Glimepiride/Vildagliptin/Metformin|DRUG: (B2) Glimepiride/Vildagliptin/Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Inspiratory Muscle Training in Addition to Pulmonary Rehabilitation in Patients With COPD Exacerbation
Status: COMPLETED
Conditions: Exacerbation Copd
Interventions: OTHER: inspiratory muscle training|OTHER: pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A 3 Month, Randomized, Open Label, Multi-center Study of Technosphere/Insulin Compared to Insulin Aspart in Subjects With Type 1 Diabetes Mellitus Receiving Insulin Glargine
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Technosphere Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Trial for Safety, Tolerability, and Immunogenicity of a Live, Attenuated, Oral Shigella/ETEC Combination Vaccine to Healthy Adults
Status: COMPLETED
Conditions: Diarrheal Disease, Infectious|Gastrointestinal Disease|Reactive Arthritis
Interventions: BIOLOGICAL: ShigETEC live, attenuated, oral vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Population Pharmacokinetics and Monte Carlo Dosing Simulations of Meropenem During the Early Phase of Severe Sepsis and Septic Shock in Critically Ill Patients in Intensive Care Units
Status: COMPLETED
Conditions: Initial Phase of Severe Sepsis and Septic Shock
Interventions: DRUG: Meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Systemic Sclerosis (SSc) Vasculopathy: Improved Clinical Monitoring and Treatment
Status: COMPLETED
Conditions: Rheumatologic Disease
Interventions: DRUG: BH4|DIAGNOSTIC_TEST: Vasculopathy assessment|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Substrate and Intervention Mechanisms for Persistent Atrial Fibrillation Trial
Status: TERMINATED
Conditions: Persistent Atrial Fibrillation
Interventions: DEVICE: Scar-Based Radio-frequency Ablation|DEVICE: Rotor Anchors Radio-frequency Ablation|DEVICE: Conventional PVI by Radio-frequency Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Respiratory Support in COVID-19 (CATCOVID-AIR)
Status: COMPLETED
Conditions: Covid19|Acute Respiratory Failure|Corona Virus Infection
Interventions: DEVICE: High-flow nasal cannula treatment|DEVICE: Continuous positive airway pressure (CPAP) treatment|DEVICE: Noninvasive ventilation treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bevacizumab With Etoposide and Cisplatin in Breast Cancer Patients With Brain and/or Leptomeningeal Metastasis
Status: COMPLETED
Conditions: Breast Neoplasms|Leptomeningeal Metastasis|Brain Metastases
Interventions: DRUG: Bevacizumab, etoposide, cisplatin|DRUG: Intrathecal methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Premixed vs Sequential Injections of Lidocaine and Bupivacaine for Supraclavicular Brachial Plexus Block in Patients Undergoing Arteriovenous Fistula Creation
Status: RECRUITING
Conditions: Premixed|Sequential|Lidocaine|Bupivacaine|Supraclavicular Brachial Plexus Block|Arteriovenous Fistula
Interventions: DRUG: Lidocaine 2% then bupivacaine 0.5%|DRUG: Lidocaine 2% and bupivacaine 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Usefulness of a Mobile Information Management System for Haemodialysis Patient
Status: COMPLETED
Conditions: Quality of Life|Drug Habit
Interventions: DEVICE: Use of DialysisNet for doctor|DEVICE: Use of Avatar Beans for patient
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prostatic Artery Embolization for the Treatment of Lower Urinary Tract Symptoms in Prostate Cancer Patients Undergoing Radiation Therapy
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: PROCEDURE: Prostatic artery embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anti-TSLP (AMG 157) Plus Antigen-Specific Immunotherapy for Induction of Tolerance in Individuals With Cat Allergy
Status: COMPLETED
Conditions: Cat Allergy|Cat Hypersensitivity
Interventions: BIOLOGICAL: AMG 157|BIOLOGICAL: Cat Immunotherapy|BIOLOGICAL: Cat Immunotherapy Placebo|BIOLOGICAL: AMG 157 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Developing a Virtual Stress Management Intervention for Spousal/Partnered Caregivers of Solid Tumor Cancer Patients.
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Lung Cancer|Colon Cancer|Solid Tumor, Adult
Interventions: BEHAVIORAL: PEPRR|BEHAVIORAL: Pep-Pal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wise Interventions and Responses to Stress
Status: COMPLETED
Conditions: Stress, Physiological|Stress, Psychological|Social Stress|Depression
Interventions: BEHAVIORAL: ITP+SA Wise intervention|BEHAVIORAL: ITP Wise intervention|BEHAVIORAL: Control condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: MRI Analysis of Glycosaminoglycan Modifications Inside the Intervertebral Disk After Distraction and Posterior Fusion
Status: ACTIVE_NOT_RECRUITING
Conditions: Lumbar Spine Instability
Interventions: DEVICE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Activity and Tolerability of Pazopanib in Advanced and/or Metastatic Liposarcoma. A Phase II Clinical Trial
Status: COMPLETED
Conditions: Advanced and / or Metastatic Liposarcoma
Interventions: DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of rTMS in Vasculitic Neuropathy
Status: TERMINATED
Conditions: Vasculitic Neuropathy
Interventions: DEVICE: Active repetitive transcranial magnetic stimulation|DEVICE: Sham repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zonisamide Augmentation of Varenicline Treatment for Smoking Cessation
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: zonisamide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Cut Off Dialysis in Systemic Inflammatory Response Syndrome Patients After Cardiac Surgery
Status: WITHDRAWN
Conditions: Systemic Inflammatory Response Syndrome|Acute Kidney Injury
Interventions: DEVICE: septeX|OTHER: standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Silver Impregnated Dressings to Reduce Wound Complications in Obese Patients at Cesarean Section
Status: TERMINATED
Conditions: Obesity|Complications; Caesarean Section, Wound
Interventions: DEVICE: Silverlon|DEVICE: Standard Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Use of Pit and Fissure Sealants in Children Requiring Caries Related Dental Extractions
Status: COMPLETED
Conditions: Dental Caries
Interventions: PROCEDURE: Pit and Fissure Sealant of permanent molars|PROCEDURE: No sealant of permanent molars
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Community-based E-Health Program for Older Adults Living With Chronic Diseases
Status: UNKNOWN
Conditions: Diabetes Mellitus|Hypertension|Hyperlipidemias
Interventions: BEHAVIORAL: Community-based E-Health Program|BEHAVIORAL: usual self-management and follow up with doctors/nurse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Janssen Asperger's MRS (Magnetic Resonance Spectroscopy Risperidone Study
Status: COMPLETED
Conditions: Asperger's Disorder
Interventions: DRUG: Risperidone|OTHER: Magnetic Resonance Spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Transversus Abdominis Plane Catheter Versus Epidural After Esophagectomy
Status: TERMINATED
Conditions: Esophageal Cancer|Pain, Postoperative
Interventions: PROCEDURE: Esophagectomy|PROCEDURE: Transversus abdominis plane catheter|PROCEDURE: Epidural
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Acceptance-Based Behavioral Intervention vs. Nutritional Counselling for Weight Loss in Psychotic Illness
Status: COMPLETED
Conditions: Psychotic Illnesses
Interventions: BEHAVIORAL: Acceptance-Based Behavioral Intervention|OTHER: Nutritional Counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of NX-019 in Patients With Advanced, Epidermal Growth Factor Receptor (EGFR) Mutant Cancer
Status: RECRUITING
Conditions: EGFR Mutation-Related Tumors
Interventions: DRUG: NX-019
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 96-hour Patch Test Study Using Healthy Human Volunteers to Assess the Skin Irritation Potential of 11 Topically Applied Formulations
Status: UNKNOWN
Conditions: Skin Irritancy Potential
Interventions: DRUG: Chlorhexidine Gluconate|DEVICE: Hibi Universal Bathing System|OTHER: 0.1% SLS|OTHER: Distilled Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis
Status: RECRUITING
Conditions: Generalized Myasthenia Gravis
Interventions: COMBINATION_PRODUCT: ALXN1720|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Rituximab and Brentuximab Vedotin for Relapsed Classical Hodgkin Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: BIOLOGICAL: Brentuximab vedotin|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Customized Neuro-Imaging Referenced Symptom Video for the Reduction of Patient and Caregiver Anxiety Around Radiation Treatment for Brain Tumors
Status: RECRUITING
Conditions: Glioblastoma|WHO Grade II Glioma|WHO Grade III Glioma
Interventions: OTHER: Educational Intervention|OTHER: Questionnaire Administration|OTHER: Survey Administration|OTHER: Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Healthy-donor Microbiome MTP-101-C in Steroid Relapse/Refractory Immune-related Cutaneous Adverse Events (irCAEs) and Immune-mediated Colitis (IMC)
Status: NOT_YET_RECRUITING
Conditions: Immune-mediated Colitis (IMC)|Immune-related Dermatitis
Interventions: BIOLOGICAL: MTP-101-C
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT