pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of HSK21542 Injection in Subjects Undergoing Hemodialysis
Status: COMPLETED
Conditions: Uremic Pruritus
Interventions: DRUG: Stage I:HSK21542 0.05 μg/kg|DRUG: Stage I:HSK21542 0.15 μg/kg|DRUG: Stage I:HSK21542 0.30 μg/kg|DRUG: Stage I:HSK21542 0.80 μg/kg|DRUG: Stage II:HSK21542 0.3 μg/kg|DRUG: Stage II:HSK21542 0.6 μg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Montelukast 5 mg Chewable
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Montelukast 5 mg chewable tablets|DRUG: Montelukast 5 mg chewable tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Long-term Extension Study to Assess Safety and Tolerability of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Pediatric Participants (Ages 6-17)
Status: ENROLLING_BY_INVITATION
Conditions: Migraine
Interventions: DRUG: Ubrogepant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1b/2 Trial of Ipilimumab, Nivolumab, and Ciforadenant (Adenosine A2a Receptor Antagonist) in First-line Advanced Renal Cell Carcinoma.
Status: RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Ipilimumab|DRUG: Nivolumab|DRUG: Ciforadenant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Glutamine for Recovery Muscle Strength
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: DIETARY_SUPPLEMENT: Glutamine|OTHER: Strength training program|OTHER: Placebo|OTHER: Dietary recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Adenoviral Conjunctivitis With SHP640 Compared to Placebo
Status: TERMINATED
Conditions: Adenoviral Conjunctivitis
Interventions: DRUG: SHP640|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Insomnia Therapy With Chronic Fatigue Syndrome
Status: COMPLETED
Conditions: Chronic Fatigue Syndrome|Behavioral Therapy Targeted to Sleep Problems
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|OTHER: Usual Care for Chronic Fatigue Syndrome (Active Control Group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Paediatric Microcuff Pressure Study
Status: COMPLETED
Conditions: Anesthesia|Pediatric|Intubation Complication
Interventions: DEVICE: Saline cuff|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Blink (First) Impression Regarding the Presence of Cancer Within Colorectal Polyps
Status: COMPLETED
Conditions: Colorectal Polyp|Colorectal Cancer|Colono
Interventions: DIAGNOSTIC_TEST: Presence of Blink impression features for cancer in colorectal polyps
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Single Doses of Oral Dexanabinol in Healthy Subjects
Status: COMPLETED
Conditions: Safety|Tolerability|Pharmacokinetics|Cancer
Interventions: DRUG: Dexanabinol Dose Level 1|DRUG: Dexanabinol Dose Level 2|DRUG: Dexanabinol Dose Level 3|DRUG: Dexanabinol Dose Level 4|DRUG: Dexanabinol Dose Level 5|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gedatolisib, Hydroxychloroquine or the Combination for Prevention of Recurrent Breast Cancer ("GLACIER")
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: Hydroxychloroquine (HCQ)|DRUG: Gedatolisib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Octreotide in Treating Patients With Cancer-Related Malignant Ascites
Status: COMPLETED
Conditions: Metastatic Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: octreotide acetate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peri-Capsular Nerve Group and Supra Inguinal Fascia Iliaca BLOCK for Analgesia and Ease of Positioning During Neuraxial Anesthesia in Hip Fracture Patients
Status: COMPLETED
Conditions: Spinal Anesthesia|Hip Fractures
Interventions: PROCEDURE: suprainguinal fascia iliaca block|PROCEDURE: pericapsular nerve group block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: BFA Treatment of Pain
Status: COMPLETED
Conditions: Musculoskeletal Pain|Acute Pain
Interventions: DEVICE: Auricular semi-permanent (ASP gold) needles|DEVICE: Intradermal (long) needles using J-type No. 2 (.18)x 15mm|DEVICE: Pyonex needles (Seirin Yellow 0.2 x 0.6mm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: eCoin for OAB Feasibility Follow-on Study
Status: COMPLETED
Conditions: Overactive Bladder|Urge Incontinence|Incontinence, Urinary|Urinary Urge Incontinence
Interventions: DEVICE: eCoin Tibial Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Budget Impact Analysis of Discontinuing Tyrosin Kinase Inhibitors in Patients With Chronic Myeloid Leukemia Achieving a Complete Molecular Response by Using Probabilistic Markov Approach
Status: COMPLETED
Conditions: Hematologic Diseases|Chronic Myeloid Leukemia
Interventions: OTHER: Budget impact
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Using Clinical Process Indicators, Patient Reported Outcome Measures (PROMs), and Patient Reported Experience Measures (PREMs) to Improve the Quality and Continuity of Care for Psychiatric Patients
Status: UNKNOWN
Conditions: Severe Mental Illness|Rehabilitation|Schizophrenia
Interventions: OTHER: Monitoring PROM @ PREM data on participating patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Aalgesic Efficacy of Erector -Spinae Technique With Levobupvicaine in Patients Undergoing Upper Abdominal Cancer Surgery
Status: UNKNOWN
Conditions: Erector Spinae Block Analgesia
Interventions: DRUG: Levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Behavioral Study to Control Blood Pressure
Status: COMPLETED
Conditions: Hypertension
Interventions: OTHER: Self-Paced Programmed Instruction (SPPI)|OTHER: Home Blood Pressure Monitor|OTHER: Usual Care|OTHER: Printed Materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Rapid Virologic Response Among HCV Patients Treated With PegIntron and Rebetol in Brazil (Study P05427)
Status: COMPLETED
Conditions: Hepatitis C, Chronic|Hepatitis C
Interventions: BIOLOGICAL: PegIntron (peginterferon alfa-2b; SCH 54031)|DRUG: Rebetol (ribavirin; SCH 18908)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Occupational Therapy and Surgery in Carpometacarpal Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis in the Carpometacarpal (CMC) Joint
Interventions: OTHER: Care as usual|OTHER: Occupational therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of GLP - 1 (7-36 Amide) on Myocardial Function Following Coronary Artery Bypass (CABG) Surgery
Status: TERMINATED
Conditions: CABG
Interventions: DRUG: Placebo|DRUG: GLP-1 (7-36) amide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exemestane, Pemetrexed Disodium, and Carboplatin in Treating Post-Menopausal Women With Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: exemestane|DRUG: pemetrexed disodium|DRUG: carboplatin|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Anti-aging Efficacy of Dermial®
Status: COMPLETED
Conditions: Skin Aging
Interventions: DIETARY_SUPPLEMENT: HA matrix ingredient|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Exploratory Lapatinib (Positron Emission Tomography) PET Study in Subjects With Breast Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Lapatinib|DRUG: [11C] lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Safety and Efficacy Study of Bevacizumab, Paclitaxel, Carboplatin Compared to Avastin® in Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Bevacizumab|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-operative Exercise During Neoadjuvant Chemotherapy in Patients With Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Prehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing the Effectiveness of IV Bezlotoxumab Versus Placebo in Decreasing Morbidity and Mortality in Patients With Fulminant C. Diff Requiring Surgery.
Status: TERMINATED
Conditions: Clostridia Difficile Colitis|Clostridium; Sepsis
Interventions: BIOLOGICAL: Bezlotoxumab|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Self-Management Supported Telerehabilitation in Children and Adolescents With Juvenile Idiopathic Arthritis
Status: RECRUITING
Conditions: Telerehabilitation|Juvenile Idiopathic Arthritis|Self-Management
Interventions: OTHER: Self-Management Supported Telerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Pigtail Catheter Versus Intercostal Tube Drainage of Non-traumatic Exudative Pleural Effusion
Status: NOT_YET_RECRUITING
Conditions: Pleural Effusion
Interventions: DEVICE: Pigtail catheter|DEVICE: Intercostal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Bio-electromagnetic Energy Regulation Therapy on Erectile Dysfunction in Patients With Multiple Sclerosis
Status: RECRUITING
Conditions: Erectile Dysfunction Due to Diseases Classified Elsewhere|Multiple Sclerosis, Relapsing-Remitting
Interventions: DEVICE: bio-electromagnetic energy regulation therapy (BEMER) machine model type: B.BOX CLASSIC, model NO: 420100, 12-15 Volt, (BEMER Int.AG, Liechtenstein product).|DEVICE: placebo BEMER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Chromium Picolinate + Biotin on Glucose and Cholesterol Control in T2DM
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Chromium Picolinate (600 mcg Cr) + biotin (2 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study on the Safety and Efficacy of Chimeric Antigen Receptor T-cell (CART) in the Treatment of Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor
Interventions: BIOLOGICAL: HER2-E-CART cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibritumomab Tiuxetan for Treatment of Non-Follicular CD20+ Indolent Lymphomas
Status: TERMINATED
Conditions: Lymphoma
Interventions: DRUG: Zevalin|DRUG: Rituximab|DRUG: ^111 In Ibritumomab Tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Use of MY-RIDE, a Just-in-time Adaptive Intervention, to Improve HIV Prevention and Substance Use in Youth Experiencing Homelessness
Status: NOT_YET_RECRUITING
Conditions: HIV Infections
Interventions: BEHAVIORAL: Attention-control group|BEHAVIORAL: MY-RIDE group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Implementing a Low FODMAP Diet in Irritable Bowel Syndrome Patients
Status: COMPLETED
Conditions: IBS - Irritable Bowel Syndrome
Interventions: OTHER: Registered dietitian|OTHER: On-line video program|OTHER: Printed handout|OTHER: Dietitian-led group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Photobiomodulation to Alter Cerebral Blood Flow and to Affect the Emotional Status of Patients With Major Depression
Status: COMPLETED
Conditions: Major Depression|Anxiety Disorder|Post-Traumatic Stress Disorder|Substance Abuse Disorder
Interventions: DEVICE: Photobiomodulation with a super-luminous light emitting diode
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide as Consolidation and Maintenance in Adults >/= 60 Years of Age With AML Following Standard Induction
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Randomized, Placebo-Controlled, Double-Blind, Dose Ranging Study, Safety, Tolerability and Immunogenicity
Status: TERMINATED
Conditions: Clostridium Difficile Infection|Clostridium Difficile Diarrhea
Interventions: BIOLOGICAL: Vaccine diluent buffer|BIOLOGICAL: Clostridium difficile toxoid vaccine (50 μg)|BIOLOGICAL: Clostridium difficile toxoid vaccine (100 μg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine in the Treatment of Breast Cancer With Low-hormone Receptor Expression After Neoadjuvant Chemotherapy
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Capecitabine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma
Status: COMPLETED
Conditions: Pleuropulmonary Blastoma|Recurrent Malignant Peripheral Nerve Sheath Tumor|Recurrent Neuroblastoma|Recurrent Rhabdomyosarcoma|Recurrent Synovial Sarcoma|Wilms Tumor
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Lorvotuzumab Mertansine|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety and Efficacy for the Combination of Durvalumab and Daratumumab in Relapsed and Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Durvalumab|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Project CASA in Promoting Smoke-Free Indoor Air Policy in Mexican American Households
Status: COMPLETED
Conditions: Cigarette Smoker|Current Smoker|Currently Living With Smoker
Interventions: OTHER: Informational Intervention|BEHAVIORAL: Smoking Cessation Intervention|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of RO4602522 in Participants With Moderate Severity Alzheimer Disease on Background Alzheimer Disease Therapy
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: RO4602522|DRUG: Placebo|DRUG: Donepezil|DRUG: Memantine|DRUG: Rivastigmine|DRUG: Galantamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study for Glimepiride + Metformin Hydrochloride (Amaryl M) Slow Release (SR)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About the Safety and Immune Activity of RSVpreF in Children 2 to <18 Years of Age
Status: COMPLETED
Conditions: RESPIRATORY SYNCYTIAL VIRUS (RSV)
Interventions: BIOLOGICAL: RSVpreF 120 µg|BIOLOGICAL: RSVpreF 60 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Safety and Efficacy of CLL1+CD33 CAR-T in Patients With R/R AML
Status: NOT_YET_RECRUITING
Conditions: AML
Interventions: BIOLOGICAL: CLL1+CD33 CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep, Cognition and Memory Disorder
Status: COMPLETED
Conditions: Sleep Architecture|Sleep Disorders|Cognitive Impairment
Interventions: OTHER: 2 night polysomnography|OTHER: battery of neuropsychological tests|OTHER: virtual reality test|OTHER: subjective evaluation of sleep and somnolence
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Skin Prick Test of KeraStat® Cream
Status: COMPLETED
Conditions: Hypersensitivity
Interventions: DEVICE: KeraStat® Cream|DEVICE: KeraStat Gel|DEVICE: Biafine|DRUG: Histamine|DRUG: Saline (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Evaluating a Digital Memory Notebook App to Improve Functional Independence
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: OTHER: Digital Notebook app|OTHER: Smart Home Prompting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Standard Versus PICO Dressings in Lower-Extremity Bypass Patients
Status: TERMINATED
Conditions: Of Bypass Graft of the Extremities|Peripheral Arterial Disease|Vascular Diseases|Cardiovascular Diseases
Interventions: DEVICE: PICO Single-Use Negative Pressure Dressings|OTHER: Sterile Gauze Dressings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Cognitive Processing Therapy in Pregnant Women With a History of Pregnancy Loss/Complication
Status: TERMINATED
Conditions: Post-traumatic Stress Disorder|Stress Disorders|Anxiety|Depression
Interventions: BEHAVIORAL: Cognitive Processing Therapy|BEHAVIORAL: Waitlist Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Caffeine on Postextubation Adverse Respiratory Events in Children With Obstructive Sleep Apnea (OSA).
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Tonsillectomy|Adenoidectomy|Postoperative Complications
Interventions: DRUG: Caffeine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Feeding Dynamic Intervention: Self Regulation of Intake in Preschoolers
Status: COMPLETED
Conditions: Children|Exogenous Obesity|Eating Behavior
Interventions: BEHAVIORAL: lifestyle counseling, parental feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Safety and Immunogenicity Study of MYOBLOC (Neurobloc; Botulinum Toxin Type B) Injectable Solution in Patients With Cervical Dystonia
Status: COMPLETED
Conditions: Cervical Dystonia
Interventions: BIOLOGICAL: Botulinum Toxin Type B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib Combined With Ibrutinib in Chronic Lymphocytic Leukemia Patients
Status: UNKNOWN
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell
Interventions: DRUG: ruxolitinib|DRUG: ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Predict the Risk of Bone Fractures With the POROUS Ultrasound Device
Status: NOT_YET_RECRUITING
Conditions: Healthy|Osteopenia|Osteoporosis
Interventions: DEVICE: Measurements with the POROUS R3C ultrasound device at the midshaft tibia|DEVICE: DXA measurement of the hip and lumbar spine|DEVICE: DXA-based Vertebral Fracture Assessment (VFA)|DEVICE: Projectional radiography of thoracic spine (alternative to DXA-based VFA, if VFA is not available)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of the Effectiveness of EMG-Biofeedback and Rebound Therapy in Patients With Endometriosis
Status: NOT_YET_RECRUITING
Conditions: Endometriosis
Interventions: DEVICE: EMG-Biofeedback|OTHER: Rebound Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Root Coverage Outcomes by NORD Flap Versus Subepithelial Connective Tissue Graft in RT1 Gingival Recession
Status: RECRUITING
Conditions: Gingival Recession
Interventions: PROCEDURE: novel overlapping rotated double (NORD) flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of a Mediterranean Diet Program for Overweight or Obese Pregnant Women in a Low-resource Clinical Setting
Status: ENROLLING_BY_INVITATION
Conditions: Gestational Weight Gain|Diet, Healthy
Interventions: BEHAVIORAL: MedDiet Program|BEHAVIORAL: ACOG-based Dietary Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: High-frequency Transcranial Random Noise Stimulation (Hf-tRNS) for Sleep Disturbances in Neurocognitive Disorders Due to Vascular Disease
Status: RECRUITING
Conditions: Sleep Disorders, Circadian Rhythm|Cognitive Impairment|Vascular Dementia
Interventions: DEVICE: Transcranial current stimulation (tCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2a Study to Determine the Dose Response Pharmacokinetics of TSX-011 (Testosterone Undecanoate) in Hypogonadal Males
Status: TERMINATED
Conditions: Hypogonadism|Hypogonadism, Male|Gonadal Disorders|Endocrine System Diseases|Testosterone Deficiency
Interventions: DRUG: TSX-011
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: US-guided OOP Internal Jugular Vein Vs IP Supraclavicular Subclavian Vein Catheterization in ICU
Status: COMPLETED
Conditions: Central Venous Catheter
Interventions: DEVICE: Catetherization approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Abciximab (ReoPro) as a Therapeutic Intervention for Sickle Cell Vaso-Occlusive Pain Crisis
Status: WITHDRAWN
Conditions: Sickle Cell Disease|Hb-SS Disease With Vasoocclusive Pain|Hemoglobin SS Disease With Vasoocclusive Crisis|Other Sickle Cell Disease With Vaso-Occlusive Pain|Hemoglobin SS Disease With Crisis
Interventions: DRUG: Abciximab|DRUG: Placebo|OTHER: Intravenous hydration|DRUG: Ibuprofen|DRUG: Parenteral narcotic|OTHER: Incentive spirometry|OTHER: Supplemental oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Modulating the nNOS System on Cardiac, Muscular and Cognitive Function in Becker Muscular Dystrophy Patients
Status: COMPLETED
Conditions: Becker Muscular Dystrophy
Interventions: DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Encapsulated Nutrients' Acute Effects on Appetite; ENcapSulated, nUtRiEnts (ENSURE)
Status: COMPLETED
Conditions: Appetite; Lack or Loss, Nonorganic Origin
Interventions: DIETARY_SUPPLEMENT: Encapsulated nutrients|DIETARY_SUPPLEMENT: Non-encapsulated nutrients|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Group-based Cognitive-behavioral Therapy for Adults With Attention-deficit/Hyperactivity Disorder Inattentive-type
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: BEHAVIORAL: Cognitive-behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: H7N9 Mix and Match With MF59 in Healthy Elderly Persons
Status: COMPLETED
Conditions: Avian Influenza
Interventions: DRUG: MF59|BIOLOGICAL: Influenza Virus Vaccine, Monovalent A/H7N9 A/Shanghai/2/2013
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: REsynchronization reVErses Remodeling in Systolic Left vEntricular Dysfunction (REVERSE)
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Cardiac Resynchronization Therapy (CRT) Device or Implantable Cardioverter Defibrillator (ICD) with CRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of SHR-A2102 With or Without Antitumor Therapy in Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: SHR-A2102|DRUG: SHR-A2102 ; Adebrelimab injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess the Immunogenicity and Safety of the Trivalent Virosomal Influenza Vaccine, Formulation of 2012-2013, in Non-Elderly Adults and Elderly Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: AdimFlu-V
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety & Efficacy Study of MRX-7EAT Patch in the Treatment of Pain of the Shoulder
Status: COMPLETED
Conditions: Bursitis|Tendonitis|Shoulder Pain
Interventions: DRUG: MRX-7EAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine in Outpatient Adults With COVID-19
Status: TERMINATED
Conditions: Coronavirus Infection
Interventions: DRUG: Hydroxychloroquine SAR321068|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azacitidine in Haploidentical Donor Hematopoietic Cell Transplantation
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome|Acute Lymphocytic Leukemia
Interventions: DRUG: Fludarabine|RADIATION: Fractionated total body irradiation|DRUG: Busulfan|DRUG: Cyclophosphamide|RADIATION: Single dose total body irradiation|DRUG: Melphalan|DRUG: Granulocyte-colony stimulating factor|PROCEDURE: Stem cell transplant|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of 'Mechanical Power' as a Predictor of Increased Serum and Pulmonary Proinflammatory Cytokine Concentrations in Patients With Acute Hypoxemic Respiratory Failure: A Prospective Observational Study
Status: RECRUITING
Conditions: Mechanical Power
Interventions: DEVICE: Mechanical ventilation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cervical Cerclage Position Throughout the Pregnancy.
Status: TERMINATED
Conditions: Cervix Uteri-Diseases
Interventions: DIAGNOSTIC_TEST: Trans vaginal sonography|DIAGNOSTIC_TEST: Vaginal examination|DIAGNOSTIC_TEST: Speculum examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of SmartSleep Technology for Improving the Efficiency and Restorative Quality of Sleep in Healthy Adults
Status: COMPLETED
Conditions: Sleep
Interventions: DEVICE: Philips SmartSleep Technology--Continuous Fixed Interval modality|DEVICE: Philips SmartSleep Technology--Block modality|DEVICE: Philips SmartSleep Technology--In-Phase Adjustable modality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Duration of ANtibiotic Therapy for CEllulitis
Status: TERMINATED
Conditions: Cellulitis|Erysipelas
Interventions: DRUG: Flucloxacillin|DRUG: Placebo (for flucloxacillin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Broccoli Extract Supplementation in Older Adults With Alcohol Use Disorder
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DIETARY_SUPPLEMENT: Generally Recognized as Safe - Sulforaphane|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Recombinant Influenza Vaccine Containing Different H3 Antigens Without or With Adjuvant in Healthy Adult Subjects
Status: COMPLETED
Conditions: Influenza Immunisation|Healthy Volunteers
Interventions: BIOLOGICAL: Quadrivalent RIV with H3 strain 1|BIOLOGICAL: Quadrivalent RIV with H3 strain 1 and adjuvant|BIOLOGICAL: Quadrivalent RIV with H3 strain 2|BIOLOGICAL: Quadrivalent RIV with H3 strain 2 and adjuvant|BIOLOGICAL: Quadrivalent RIV with 2018-2019 NH H3 strain|BIOLOGICAL: Quadrivalent RIV with 2018-2019 NH H3 strain and adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Feasibility of Teleglaucoma Versus Conventional Clinical Evaluation for Diagnostic Accuracy and Management Recommendations in Patients With Glaucoma
Status: COMPLETED
Conditions: Teleglaucoma|Teleophthalmology|Glaucoma
Interventions: DIAGNOSTIC_TEST: Teleglaucoma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: The Prognostic Capabilities Of A Preoperative Six-Minute Walk Test To Independently Inform Cardiovascular Risk After Major Noncardiac Surgery
Status: UNKNOWN
Conditions: Noncardiac Surgery|Postoperative Myocardial Infarction|Postoperative Death|Risk Assessment
Interventions: OTHER: Six-minute walk test to perform before surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Electrostimulation Program During Dialysis Sessions in Chronic Renal Failure Patients
Status: COMPLETED
Conditions: Chronic Renal Failure (CRF)
Interventions: DEVICE: electrostimulation program (Rehab 400)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FLOW Evaluation to Guide Revascularization in Multi-vessel ST-elevation Myocardial Infarction
Status: UNKNOWN
Conditions: Acute ST Segment Elevation Myocardial Infarction|Acute Myocardial Infarction|Multi Vessel Coronary Artery Disease
Interventions: PROCEDURE: Angiography guided PCI|DEVICE: Fractional Flow Reserve (FFR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-Efficacy Support on Medication Adherence and Self-Efficacy Levels in Hypertension Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: self-efficacy support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: New Moms Mood Tracking & Wellbeing
Status: COMPLETED
Conditions: Depression|Perinatal Depression|Anxiety|Pregnancy Related
Interventions: BEHAVIORAL: Online therapy with coaching within STAND|BEHAVIORAL: Clinical care within STAND|OTHER: Perinatal Psychiatric Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study to Evaluate the Effectiveness of Mircera Treatment for Renal Anemia in Pre-dialysis Participants With Chronic Kideny Disease (CKD)
Status: COMPLETED
Conditions: Kidney Disease, Chronic
Interventions: DRUG: Methoxy polyethylene glycol-epoetin beta
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Preoperative Intravenous Iron in Anaemic Colorectal Cancer Surgical Patients
Status: COMPLETED
Conditions: Anemia, Iron-Deficiency|Colorectal Cancer
Interventions: DRUG: iron isomaltoside(Monofer®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Temperature on Evaporative Dry Eye
Status: NOT_YET_RECRUITING
Conditions: Dry Eye
Interventions: DRUG: Diquafosol tetrasodium|DEVICE: Heated eye mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of a Mental Health Scale for Young People With Chronic Stomach Symptoms
Status: NOT_YET_RECRUITING
Conditions: Functional Gastrointestinal Disorders|Gastroparesis|Vomiting; Cyclical|Nausea|Vomiting|Rumination Syndrome|Aerophagy|Dyspepsia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility and Acceptability of a Healthy Nordic Diet Intervention in Depressed and Non-depressed Adults
Status: COMPLETED
Conditions: Depression|Major Depressive Disorder
Interventions: OTHER: Control Diet (CD)|OTHER: Healthy Nordic Diet (ND)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Circulating T Cells and Tumor Infiltrating Lymphocytes (TILs) During / After Pre-Surgery Chemotherapy in Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Ipilimumab|DRUG: Paclitaxel, Cisplatin, Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Second-Line Uterotonics in Postpartum Hemorrhage: A Randomized Clinical Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Postpartum Hemorrhage|Uterine Atony
Interventions: DRUG: 15-methyl prostaglandin F2α|DRUG: Methylergonovine Maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Frequency Impulse Therapy for Neuropathic Pain in NMOSD
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuromyelitis Optica
Interventions: DEVICE: High Frequency Impulse Therapy|DEVICE: High Frequency Impulse Therapy - Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mitoxantrone, Etoposide, and Vinorelbine As Second-Line Therapy in Treating Patients With Metastatic Prostate Cancer That Did Not Respond to Hormone Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: etoposide|DRUG: mitoxantrone hydrochloride|DRUG: prednisone|DRUG: vinorelbine tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Improving Glycemic Control Using a Virtual Weight Control Program Among Adults With Type 2 Diabetes
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 2|Obesity
Interventions: BEHAVIORAL: WW Intervention|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Etoposide+Cytarabine+PEG-rhG-CSF as First Line Mobilization Regimen of Hematopoietic Stem Cells in Patients With Hematological Malignancies
Status: RECRUITING
Conditions: Lymphoma|Multiple Myeloma
Interventions: DRUG: Etoposide|DRUG: Cytarabine|DRUG: PEG-rhG-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SHR-A1811 Versus Investigator's Chemotherapy in Recurrent/Metastatic Breast Cancer Clinical Trial
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: SHR-A1811|DRUG: Capecitabine/Eribulin/Gemcitabine/Paclitaxel/Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detachable String Magnetically Controlled Capsule Endoscopy for Detecting High-risk Varices in Compensated Cirrhosis
Status: UNKNOWN
Conditions: Compensated Cirrhosis|Gastroesophageal Varices Bleeding
Interventions: DIAGNOSTIC_TEST: Detachable string magnetically controlled capsule endoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Laparoscopic Supracervical Hysterectomy and Sacropexy Versus Hysteropexy Study
Status: UNKNOWN
Conditions: Uterus Prolapse
Interventions: PROCEDURE: Laparoscopic Supracervical Hysterectomy and Sacropexy|PROCEDURE: Laparoscopic Hysteropexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Value of Palliative Primary Tumor Resection in Metastatic Colon Cancer
Status: RECRUITING
Conditions: Metastatic Colon Cancer|Surgery
Interventions: PROCEDURE: resection of primary tumor|DRUG: XELOX|DRUG: mFOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Sexual Health and Amputation Focused Education on Regulation of Glucose and Amputation Prevention
Status: TERMINATED
Conditions: Diabetic Ulcers on Both Feet|Amputation; Traumatic, Limb|Sexual Dysfunction|Diabetic Foot Ulcer Ischemic
Interventions: BEHAVIORAL: Diabetes education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Reduction of Mortality Prior to and During the First 90 Days of Dialysis Through a Renal Rehabilitation Program
Status: COMPLETED
Conditions: Chronic Kidney Disease|End Stage Kidney Disease|Cardiovascular Disease
Interventions: BEHAVIORAL: exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Isolagen TherapyTM in Treatment of Facial Wrinkles and Creases
Status: COMPLETED
Conditions: Facial Wrinkles and Creases
Interventions: BIOLOGICAL: Autologous Human Fibroblasts (azficel-T)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 111 Indium CHX-A DTPA Trastuzumab (Indium-Herceptin) for Imaging Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Prostate Cancer|Lung Cancer|Colon Cancer
Interventions: DRUG: 111Indium CHX-A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Adjunctive Zonisamide in Paediatric Partial Onset Seizures (CATZ Study)
Status: COMPLETED
Conditions: Epilepsy; Paediatric Partial Onset Seizures
Interventions: DRUG: Zonisamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Performance Evaluation of the Micromedic BRONJ Risk Assessment in Vitro Diagnostic Assay
Status: UNKNOWN
Conditions: Bisphosphonate-related Osteonecrosis of the Jaw
Interventions: GENETIC: BRONJ
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Combined Cortical/Subcortical Recording and Stimulation as a Circuit-Oriented Treatment for Obsessive-Compulsive Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Obsessive Compulsive Disorder
Interventions: DEVICE: Medtronic Percept Deep Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and Relatlimab in Treating Participants With Advanced Chordoma
Status: COMPLETED
Conditions: Chordoma|Locally Advanced Chordoma|Metastatic Chordoma|Unresectable Chordoma
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Relatlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: caBozantinib in Pre-treated pAtients With Metastatic COlorectal Cancer.
Status: ACTIVE_NOT_RECRUITING
Conditions: Refractory Colorectal Adenocarcinoma
Interventions: DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study On Extracorporeal Shock Wave Therapy For Rotator Cuff Injuries
Status: RECRUITING
Conditions: Rotator Cuff Injuries
Interventions: DEVICE: Extracorporeal shock wave therapy|OTHER: conventional rehabilitation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Local Wound Anesthesia in Spine Surgery
Status: COMPLETED
Conditions: Surgical Wound|Orthopedic Disorder of Spine
Interventions: DRUG: Infiltration with NaCl|DRUG: Infiltration with Ropivacain|DRUG: Infiltration with a combination of Levobupivacaine and Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Miralax (PEG 3350) vs. Golytely as Bowel Preparation for Screening Colonoscopy
Status: COMPLETED
Conditions: Colon Cancer
Interventions: DRUG: PEG-3350 and Gatorade|DRUG: Golytely 4 liters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Stability of Bupivacaine With and Without Adrenaline for Paracervical Block for Cervical Conization
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia
Interventions: DRUG: Bupivacaine|DRUG: Adrenaline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect and Safety Of Detrol LA In Men With Overactive Bladder Symptoms With Or Without Bladder Outlet Obstruction
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DRUG: Tolterodine ER 4 mg QD|DRUG: Tamsulosin 0.4 mg QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT