pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Spirulina on Liver Fibrosis by Transient Elastography in Beta Thalassemic Children With Hepatitis C
Status: COMPLETED
Conditions: Beta Thalassemia Major
Interventions: DIETARY_SUPPLEMENT: Spirulina
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Vibration Therapy in Addition to Routine Physical Therapy in Patients With Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy
Interventions: OTHER: Routine Physical Therapy|OTHER: Vibration Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Tacrolimus 0.03% Ointment for Intractable Allergic Conjunctivitis: An Open Label Pilot Study
Status: UNKNOWN
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Tacrolimus 0.03% ointment (Protopic)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maine Implementation Study - Phase III
Status: COMPLETED
Conditions: Anxiety|Trauma|Depression|Problem Behavior
Interventions: BEHAVIORAL: Usual Care Treatment|BEHAVIORAL: Modular Approach to Therapy for Children
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Oxford-AstraZeneca COVID-19 Vaccine as a 2nd Booster, the REFORCO-Brazil Study
Status: COMPLETED
Conditions: COVID-19
Interventions: OTHER: ChAdOx1 nCOV-19 vaccine (Vaxzeria)|OTHER: BNT162b2 (Pfizer)|OTHER: Ad26.COV2.S (Janssen)|OTHER: CoronaVac (Sinovac)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bipolar Androgen Therapy (BAT) and Radium-223 (RAD) in Metastatic Castration-resistant Prostate Cancer (mCRPC)
Status: RECRUITING
Conditions: Prostate Adenocarcinoma|Metastatic Prostate Adenocarcinoma|Castration-resistant
Interventions: RADIATION: radium-223|DRUG: Bipolar Androgen Therapy (BAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Observation Registry Study on the Alimentary Reconstruction After Radical Proximal Gastrectomy
Status: RECRUITING
Conditions: Proximal Gastric Adenocarcinoma|Reconstruction
Interventions: PROCEDURE: Double tract reconstruction|PROCEDURE: Gastric conduit reconstruction|PROCEDURE: Other reconstructions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrafiltration Versus IV Diuretics in Worsening Heart Failure
Status: RECRUITING
Conditions: Heart Failure (for Example, Fluid Overload)
Interventions: DEVICE: Aquadex Smartflow® System|DRUG: IV Loop Diuretics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of Taspoglutide on Gastric Emptying in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Placebo|DRUG: taspoglutide|DRUG: taspoglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention Using Vitamin D for Elevated Urinary Albumin Treated With Losartan in Diabetes (IDEAL)
Status: TERMINATED
Conditions: Diabetic Nephropathies
Interventions: DIETARY_SUPPLEMENT: Calcitriol|DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bryostatin 1 Plus Vincristine in Treating Patients With Progressive or Relapsed Non-Hodgkin's Lymphoma After Bone Marrow or Stem Cell Transplantation
Status: COMPLETED
Conditions: Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Nodal Marginal Zone B-cell Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Small Lymphocytic Lymphoma|Splenic Marginal Zone Lymphoma
Interventions: DRUG: bryostatin 1|DRUG: vincristine sulfate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: T Acute Lymphoblastic Leukemia|T Lymphoblastic Lymphoma
Interventions: DRUG: Asparaginase|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Daunorubicin Hydrochloride|DRUG: Dexamethasone|DRUG: Doxorubicin Hydrochloride|OTHER: Laboratory Biomarker Analysis|DRUG: Leucovorin Calcium|DRUG: Mercaptopurine|DRUG: Methotrexate|DRUG: Nelarabine|DRUG: Pegaspargase|DRUG: Prednisone|RADIATION: Radiation Therapy|DRUG: Thioguanine|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib, Doxorubicin Hydrochloride Liposome, and Dexamethasone Followed by Thalidomide and Dexamethasone With or Without Bortezomib in Treating Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: bortezomib|DRUG: dexamethasone|DRUG: pegylated liposomal doxorubicin hydrochloride|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Plus High-Dose 5-Fu/Leucovorin in the Treatment of Advanced or Metastatic Carcinoma of the Biliary Tract
Status: COMPLETED
Conditions: Biliary Tract Disease
Interventions: DRUG: Gemcitabine+5FU+Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study to Evaluate Efficacy and Safety of NU100 in Patients With Relapsing Remitting Multiple Sclerosis (RRMS)
Status: UNKNOWN
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: BIOLOGICAL: NU100|BIOLOGICAL: Placebo|BIOLOGICAL: rhIFN beta-1b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Explore the Role of Gut Flora in Crohn's Disease
Status: UNKNOWN
Conditions: Crohn Disease|Crohn Colitis|Crohn's Ileocolitis|Crohn Ileitis|Crohn Disease of Ileum|Crohn's Disease Relapse|Crohn's Gastritis|Crohns Disease Aggravated|Crohn Disease in Remission|Crohn's Jejunitis|Crohn's Duodenitis|Crohn's Disease of Pylorus|Crohn's Esophagitis|Crohn's
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acetaminophen for Oxidative Stress After Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Congenital Heart Disease|Cardiopulmonary Bypass
Interventions: OTHER: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Fluticasone-Vilanterol Once Daily Dose for the Treatment of Mild Asthma in Adults
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: fluticasone-vilanterol|DRUG: Standard Preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Phenylephrine and Norepinephrine for Spinal-induced Hypotension
Status: COMPLETED
Conditions: Spinal Induced-hypotension
Interventions: DRUG: Norepinephrine|DRUG: Phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bleomycin Jet Injections in Keloids
Status: ACTIVE_NOT_RECRUITING
Conditions: Keloid
Interventions: DRUG: Bleomycin|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antispastic Effect of Transcranial Magnetic Stimulation in Patients With Cerebral and Spinal Spasticity
Status: UNKNOWN
Conditions: Spasticity, Multiple Sclerosis, Stroke, Trauma
Interventions: DEVICE: Transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: BiZact Tonsillectomy in the Pediatric Population
Status: COMPLETED
Conditions: Tonsillectomy|Tonsillitis Chronic|Hemorrhage|Postoperative Pain|Postoperative Hemorrhage|Surgery--Complications|Otorhinolaryngologic Diseases
Interventions: DEVICE: BiZact|PROCEDURE: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Topical Centella Asiatica and the Cosmetic Appearance of Stretch Marks
Status: COMPLETED
Conditions: Stretch Marks|Striae Distensae|Cosmetic Appearance of Stretch Marks
Interventions: OTHER: Placebo Vehicle Cream|OTHER: Centella Asiatica Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Home-based Treatment Using the Sidekick Tool for Pain Relief in Patients With Iliotibial Band Syndrome
Status: NOT_YET_RECRUITING
Conditions: Iliotibial Band Syndrome
Interventions: DEVICE: Instrument Assisted Soft Tissue Mobilization device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incidence of Postoperative Pain After Glide Path Preparation Using Three Different Instruments
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: R-Pilot®|PROCEDURE: ProGlider®|PROCEDURE: Manual preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Priming the Infusion System on the Performance of Target-controlled Infusion of Remifentanil
Status: COMPLETED
Conditions: Intravenous Drug Usage
Interventions: DEVICE: Remi50 with prime|DEVICE: Remi20 with prime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Quick Returns - Sleep, Cognitive Functions and Individual Differences
Status: COMPLETED
Conditions: Shift Work Schedule|Sleep Deprivation
Interventions: OTHER: Short rest (8 hour) between two consecutive shifts.|OTHER: 16 hour rest opportunity between to consecutive shifts.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of MCT-SR in Patients With Gastritis
Status: COMPLETED
Conditions: Acute Gastritis|Chronic Gastritis
Interventions: DRUG: MCT-SR|DRUG: Mucosta Tab.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema
Status: RECRUITING
Conditions: Hereditary Angioedema|Hereditary Angioedema Type I|Hereditary Angioedema Type II|Hereditary Angioedema Types I and II|Hereditary Angioedema Attack|Hereditary Angioedema With C1 Esterase Inhibitor Deficiency|Hereditary Angioedema - Type 1|Hereditary Angioedema - Type 2|C1 Esterase Inhibitor [C1-INH] Deficiency|C1 Esterase Inhibitor Deficiency|C1 Esterase Inhibitor, Deficiency of|C1 Inhibitor Deficiency
Interventions: DRUG: deucrictibant low dose|DRUG: deucrictibant medium dose|DRUG: deucrictibant high dose|DRUG: deucrictibant selected dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Heart Stem Cells to Achieve Myocardial Regeneration
Status: TERMINATED
Conditions: Myocardial Infarction
Interventions: BIOLOGICAL: CAP-1002 Allogeneic Cardiosphere-Derived Cells|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Results of Preimplantation Genetic Diagnosis and Preimplantation Genetic Screening of Embryos Obtained From GnRH-agonist Long and GnRH-antagonist Ovarian Stimulation Protocol
Status: UNKNOWN
Conditions: Embryo's Genetic and Chromosomal Quality
Interventions: DRUG: ghrh antagonist (cetrotide/orgalutran)|DRUG: gnrh agonist (suprefact)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Predictive Value of Innovative Prognostic Markers (Gut Microbiota, Sarcopenia, Metabolic Syndrome and Obesity) on Surgical and Oncologic Results in the Management of Sporadic Colorectal Adenocarcinoma.
Status: UNKNOWN
Conditions: Colorectal Neoplasms|Microbiota|Prognosis|Metabolic Syndrome|Sarcopenia
Interventions: OTHER: no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Regorafenib Combined With TAS-102 Versus Regorafenib Monotherapy in Third or Later Line Therapy of mCRC
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Regorafenib|DRUG: Trifluridine/Tipiracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the SCL16A11 Risk Haplotype on Treatments to Prevent Type 2 Diabetes
Status: COMPLETED
Conditions: PreDiabetes
Interventions: DRUG: Life Style Intervention + Metformin|BEHAVIORAL: Life Style Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Impact of a Seated Compact Elliptical Trainer on Individuals With Knee OA
Status: RECRUITING
Conditions: Osteoarthritis|Knee Osteoarthritis|Arthritis|Joint Diseases|Musculoskeletal Diseases|Rheumatic Diseases
Interventions: OTHER: Exercise for Knee Osteoarthritis|DEVICE: Compact seated elliptical exercise machine- Cubii JR-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cutaneous Microcirculation After Remote Ischemic Preconditioning
Status: COMPLETED
Conditions: Burn Injury|Acute Wound|Chronic Wound
Interventions: PROCEDURE: Intervention: Remote Ischemic Preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 1 Study of Tremelimumab, Durvalumab, High-dose Chemotherapy, + Autologous Stem Cell Transplant
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Tremelimumab|DRUG: Durvalumab|BIOLOGICAL: Prevnar-13|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Helichrysum Italicum Infusion Ingestion in Humans
Status: COMPLETED
Conditions: Energy Expenditure|Substrate Oxidation|Blood Pressure
Interventions: DIETARY_SUPPLEMENT: Helichrysum italicum infusion|OTHER: Hot water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing the Efficacy of fMRI-Guided vs. Standard iTBS in Treating Depression
Status: RECRUITING
Conditions: Depression|Depressive Disorder, Major|Depressive Episode
Interventions: DEVICE: repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prognostic Impact of Sleep Apnea on Cardiovascular Morbidity and Mortality, in End Stage Renal Disease Patients
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea|End Stage Renal Disease
Interventions: OTHER: No Sleep Apnea|OTHER: Sleep Apnea - untreated|DEVICE: Sleep Apnea - treated
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility of Assessing Lymphoma Response to Precise Local Injection of Candidate Chemotherapy Agents
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Multiple drug microinjection: rituximab, vincristine, doxorubicin, bendamustine, prednisolone or a combination of them
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Quadratus Lumborum Block Versus Epidural for Laparoscopic Nephrectomy Kidney Donor
Status: COMPLETED
Conditions: Renal Transplant Donor of Left Kidney
Interventions: PROCEDURE: Quadratus Lumborum Block|PROCEDURE: Continuous Epidural
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Postoperative Analgesic Efficacy of Transversalis Fascia Plan Block and Erector Spina Plan Block
Status: COMPLETED
Conditions: Regional Anesthesia
Interventions: DEVICE: Low frequency convex probe (ESAOTE Fixed Color Doppler Ultrasonography Device, Italy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Role of Vitamin C at 6 Months on Incidence of Complex Regional Pain Syndrome Type I in Upper Limb Surgery
Status: RECRUITING
Conditions: Complex Regional Pain Syndrome (CRPS) TYPE I
Interventions: DRUG: Vitamin C|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Dose Timing (Morning vs Evening) of Endocrine Therapy and Its Effects on Tolerability and Compliance
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: Morning administration of endocrine therapy|OTHER: Evening administration of endocrine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leflunomide 20 mg Tablets, Non-Fasting
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ARAVA® 20 mg tablets|DRUG: Leflunomide 20 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Brivanib and Best Supportive Care (BSC) With Placebo and BSC for Treatment of Liver Cancer in Asian Patients Who Have Failed Sorafenib Treatment
Status: TERMINATED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Brivanib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-Human CD45 Monoclonal Antibodies in Patients With Advanced Leukemia Prior to Allogeneic Stem Cell Transplantation
Status: COMPLETED
Conditions: LEUKEMIA
Interventions: DRUG: CAMPATH-1H|DRUG: Anti-CD45|DRUG: Ara-C|DRUG: Cyclophosphamide|DRUG: Mesna|RADIATION: Total Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention on Osteoporosis and Chronic Kidney Disease-mineral and Bone Disorder (CKD-MBD)
Status: TERMINATED
Conditions: Osteoporosis, Postmenopausal
Interventions: BEHAVIORAL: diet and exercise suggestion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zibotentan and Dapagliflozin in Patients With Type 2 Diabetes and Elevated Albuminuria
Status: ENROLLING_BY_INVITATION
Conditions: Chronic Kidney Diseases
Interventions: DRUG: Zibotentan|DRUG: Dapagliflozin|DRUG: Placebo|DRUG: Dapagliflozin and Zibotentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Supplemental Iron Improves Submaximal Exercise Performance in Non-anemic Iron Depleted Women
Status: COMPLETED
Conditions: Iron Deficiency (Without Anemia)
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Ferrous sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Community Intervention to Improve CVD Risk Factor Control in Young American Indians
Status: NOT_YET_RECRUITING
Conditions: Cholesterol, Elevated|Diabetes Mellitus
Interventions: OTHER: Guided management|OTHER: Self management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Integration of Augmented Reality in Expressive Art Therapy for Borderline Personality Features
Status: COMPLETED
Conditions: Self Destructive Behavior|Mood Disturbance|Self Esteem
Interventions: BEHAVIORAL: Art based Augmented Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Digital Chest-X-ray (CXR) to Assess Lung Recruitment in ARDS
Status: TERMINATED
Conditions: Acute Respiratory Distress Syndrome (ARDS)
Interventions: OTHER: PEEP of 5 or 15 cm H2O
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy Comparing Daily and After-each-case Room Disinfection.
Status: COMPLETED
Conditions: Daily Room Disinfection|After-each-case Room Disinfection
Interventions: OTHER: after-each-case room disinfection|OTHER: daily room disinfection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Anti-viral Effects of Azithromycin in Patients With Asthma and COPD
Status: UNKNOWN
Conditions: Asthma|COPD|Exacerbation Copd|Asthma; Eosinophilic|Bronchial Diseases|Lung Diseases, Obstructive|Lung Diseases|Immune System Diseases
Interventions: DRUG: Azithromycin|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resveratrol-Leucine Metabolite Synergy in Pre-diabetes
Status: COMPLETED
Conditions: Impaired Glucose Tolerance
Interventions: DIETARY_SUPPLEMENT: Resveratrol|DIETARY_SUPPLEMENT: resveratrol /HMB|OTHER: Placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive-Behavioral Treatment of Attention Deficit Hyperactivity Disorder (ADHD) in College Students - Study 1
Status: RECRUITING
Conditions: ADHD
Interventions: BEHAVIORAL: Cognitive-Behavioral Therapy Targeting Executive Dysfunction in College Students with ADHD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endocannabinoid Control of Microglia Activation as a New Therapeutic Target in the Treatment of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Placebo|DRUG: Cannabidiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Single Doses of GSK962040 in Critically Ill Patients With Enteral Feed Intolerance
Status: COMPLETED
Conditions: Gastroparesis
Interventions: DRUG: GSK962040 (50 mg)|DRUG: Placebo|DRUG: GSK962040 (75 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Active City of Liverpool Active Schools and SportsLinx Project: a Clustered Randomised Controlled Trial
Status: COMPLETED
Conditions: Physical Activity|Health Behavior
Interventions: BEHAVIORAL: High intensity physical activity (HIPA)|BEHAVIORAL: Fundamental movement skill (FMS)|BEHAVIORAL: Physical activity signposting (PASS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chronic Inflammatory Activation in Fat Tissue: An Atherogenic Factor in Severe Coronary Artery Disease
Status: TERMINATED
Conditions: Severe Coronary Artery Disease|Obesity|Impaired Glucose Tolerance
Interventions: OTHER: exercise training|OTHER: exercise training + metformin|OTHER: exercise training + glitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of the PIEB Versus CEI on the Quality of Postoperative Recovery in Patients Undergoing VATS Lobectomy
Status: RECRUITING
Conditions: Video-assisted Thoracic Surgery
Interventions: PROCEDURE: programmed intermittent epidural bolus|PROCEDURE: continuous epidural infusion|DRUG: ropivacaine and sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Evolution of Genes Mutation Related With Gastrointestinal Stromal Tumors
Status: COMPLETED
Conditions: Full Gene Sequences of c-KIT、PDGFRA and DOG1 Are Analyzed With the Screening-sequencing Approach|Investigate the Characteristics and Variations Associated With the Different Gene Mutations of c-KIT、PDGFRA and DOG1 in GIST Patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anterolateral Versus Posterior Approach for Total Hip Arthroplasty After Displaced Femoral Neck Fracture
Status: TERMINATED
Conditions: Femur Fracture
Interventions: PROCEDURE: posterior approach|PROCEDURE: anterolateral approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shenqi Fuzheng Injection for the Treatment of Cancer-related Fatigue in Chemo Patients With Digestive Tract .
Status: UNKNOWN
Conditions: Digestive Tract
Interventions: DRUG: shenqifuzheng|DRUG: 0.9%sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Naloxone in Treating Constipation in Patients Who Are Receiving Opioids for Chronic Pain
Status: UNKNOWN
Conditions: Constipation, Impaction, and Bowel Obstruction|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: naloxone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combined Effects of Early Behavioral Intervention and Propranolol on ASD
Status: COMPLETED
Conditions: Autism
Interventions: DRUG: Propranolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Descriptive and Evaluation Study of the Use of Pulmonary Ultrasound in the Initial Management of Pregnant Women in the Context of COVID-19
Status: TERMINATED
Conditions: Pregnant Women Suspected of COVID-19
Interventions: DEVICE: Performing of lung ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Multicenter Randomized Study of Vitamin D Combined With HD-DXM Versus HD-DXM for the Treatment of ITP
Status: UNKNOWN
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Rocaltrol|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib Plus Toripalimab for Platinum-Resistant Recurrent Ovarian Cancer
Status: RECRUITING
Conditions: Recurrent Ovarian Carcinoma
Interventions: DRUG: Lenvatinib+Toripalimab.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Efficacy of Olanzapine With Short-acting 5HT3 Inhibitors in Chemotherapy-induced Nausea & Vomiting (CINV) Prophylaxis
Status: UNKNOWN
Conditions: Emesis|Vomiting|Nausea Post Chemotherapy|Nausea|Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Olanzapine|DRUG: Aprepitant Pill|DRUG: Ondansetron|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microneedle Array Plus Doxorubicin in Cutaneous Squamous Cell Cancer (cSCC)
Status: RECRUITING
Conditions: Cutaneous Squamous Cell Carcinoma|Skin Cancers - Squamous Cell Carcinoma
Interventions: DRUG: Microneedle Array Doxorubicin (MNA-D)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Pembrolizumab Versus Observation in Patients With Merkel Cell Carcinoma After Surgery, STAMP Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Pathologic Stage I Cutaneous Merkel Cell Carcinoma AJCC v8|Pathologic Stage II Cutaneous Merkel Cell Carcinoma AJCC v8|Pathologic Stage III Cutaneous Merkel Cell Carcinoma AJCC v8
Interventions: OTHER: Best Practice|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Pembrolizumab|PROCEDURE: Positron Emission Tomography|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of 4Fluart ID Suspension for Injection in Adult Subjects
Status: COMPLETED
Conditions: Human Influenza
Interventions: BIOLOGICAL: 4Fluart ID suspension for injection study drug 1 µg/0.1 ml, influenza vaccine (whole virion, inactivated, adjuvanted)|BIOLOGICAL: 4Fluart ID suspension for injection study drug 2 µg/0.1 ml, influenza vaccine (whole virion, inactivated, adjuvanted)|BIOLOGICAL: 3Fluart suspension for injection, influenza vaccine (whole virion, inactivated, adjuvanted)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of KHK4827 (Brodalumab) in Subjects With Moderate to Severe Psoriasis in Korea
Status: COMPLETED
Conditions: Moderate to Severe Plaque Psoriasis
Interventions: DRUG: KHK4827|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Supporting Smoke-Free Policy Compliance in Public Housing
Status: RECRUITING
Conditions: Smoking|Smoking Cessation|Smoking Reduction|Smoking Behaviors
Interventions: BEHAVIORAL: Reduction (relocation and reduction of personal smoking) and cessation|BEHAVIORAL: Resident Endorsement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Negative Pressure Dressing Therapy in Soft Tissue Sarcoma Surgery
Status: TERMINATED
Conditions: Sarcoma|Wound Infection
Interventions: DEVICE: Negative Pressure Wound Therapy (ActivVAC, KCI)|DEVICE: Standard dressings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomised Trial to Evaluate the Antiviral Efficacy and Safety of Treatment With 500 mg Tipranavir (TPV) Plus 100 mg or 200 mg Ritonavir (RTV) p.o. BID in Comparison to 400 mg Lopinavir (LPV) Plus 100 mg RTV p.o. BID in Combination With Standard Background Regimen in ARV Therapy naïve Patients.
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: TPV500mg/RTV200mgBID|DRUG: TPV500mg/RTV100mgBID|DRUG: LPV400mg/RTV100mgBID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Pentamidine (7mg/kg) for Patients With Cutaneous Leishmaniasis Caused by L. Guyanensis
Status: COMPLETED
Conditions: Cutaneous Leishmaniases
Interventions: DRUG: Single dose of Pentamidine|DRUG: Two doses of Pentamidine|DRUG: Three doses of Pentamidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on FOLFOX6 as First-line Therapy to Treat Recurrent or Metastatic Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: FOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ethyl Chloride Topical Anesthesia Application on the Pain Perception During Intra-oral Injections in Children in Comparison to Benzocaine Gel.
Status: RECRUITING
Conditions: Dental Caries in Children|Anesthesia, Local|Injection Site Discomfort
Interventions: OTHER: Ethyl Chloride spray (group A)|OTHER: Benzocaine gel 20% (group B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Exploring the Effect of Interactive Board Game Health Education on Improving Stroke Knowledge and Health Literacy in Community-Dwelling Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke
Interventions: BEHAVIORAL: Interactive board game health education|BEHAVIORAL: Conventional health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Colesevelam in Subjects With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Hyperlipidemias
Interventions: DRUG: Colesevelam HCl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of GP40081 Сompared to NovoMix® 30 FlexPen® in Type 2 Diabetes Mellitus Patients
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Diabetes Mellitus
Interventions: DRUG: GP40081|DRUG: NovoMix 30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weight Loss and Maintenance for Individuals With Intellectual Developmental Disabilities (IDD)
Status: COMPLETED
Conditions: Weight Loss
Interventions: DIETARY_SUPPLEMENT: Modified Stop Light Diet (SLDm)|DIETARY_SUPPLEMENT: Recommended Care Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-FDG PET/CT Guided Reduced-dose Radiotherapy for Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: RADIATION: Reduced dose|RADIATION: Conventional dose|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Efficacy, PK, PD and Immunogenicity of Cipaglucosidase Alfa/Miglustat in IOPD Subjects Aged 0 to <18
Status: RECRUITING
Conditions: Glycogen Storage Disease Type II Infantile Onset
Interventions: BIOLOGICAL: Cipaglucosidase alfa|DRUG: Miglustat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma Multiforme
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma
Interventions: PROCEDURE: Standard surgery|RADIATION: Intraoperative radiotherapy|RADIATION: Radiochemotherapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Adenosine in the Release of VEGF and Cytokines
Status: TERMINATED
Conditions: Inflammation
Interventions: DRUG: Adenosine|DRUG: Sodium Nitroprusside|DRUG: Adenosine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Dalteparin in Preventing Blood Clots in Patients With Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer|Thromboembolism
Interventions: DRUG: dalteparin|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Laparoscopic Rectopexy for Rectal Prolapse
Status: COMPLETED
Conditions: Rectal Prolapse
Interventions: PROCEDURE: Laparoscopic posterior rectopexy|PROCEDURE: Laparoscopic anterior mesh rectopexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MS-275 and GM-CSF in Treating Patients With Myelodysplastic Syndrome and/or Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphocytic Leukemia
Status: COMPLETED
Conditions: Adult Acute Lymphoblastic Leukemia in Remission|Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Chronic Myelomonocytic Leukemia|de Novo Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Refractory Anemia|Refractory Anemia With Excess Blasts|Refractory Anemia With Ringed Sideroblasts|Refractory Cytopenia With Multilineage Dysplasia|Secondary Acute Myeloid Leukemia|Secondary Myelodysplastic Syndromes|Untreated Adult Acute Lymphoblastic Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: entinostat|DRUG: sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Risk Estimator for Rheumatoid Arthritis Family Study
Status: COMPLETED
Conditions: First Degree Relatives of Rheumatoid Arthritis Patients
Interventions: BEHAVIORAL: PRE-RA|BEHAVIORAL: PRE-RA Plus|BEHAVIORAL: General Rheumatoid Arthritis Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: FITT Exercise Counseling With Interactive Accelerometry and Physical Activity in Adolescents at Increased Risk of Early Cardiovascular Disease: A Pilot Study
Status: COMPLETED
Conditions: Coronary Artery Disease Risk High
Interventions: DEVICE: BodyMedia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of an Online Self-help Psychological Intervention on Non-ICU Specialty Care During the COVID-19 Outbreak
Status: COMPLETED
Conditions: SARS-CoV-2 Infection|Staff Attitude|Anxiety|Mental Health Issue
Interventions: PROCEDURE: Online-based self-help psychological intervention|PROCEDURE: Provide online mental health knowledge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alveolar Cleft Grafting by Double Iliac Bone Blocks Versus Iliac Spongy Bone From Anterior Iliac Crest
Status: UNKNOWN
Conditions: Alveolar Cleft
Interventions: PROCEDURE: Grafting of the alveolar cleft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prasterone (DHEA) for the Treatment of Hypoactive Sexual Desire Disorder (HSDD) - Second Study
Status: WITHDRAWN
Conditions: Hypoactive Sexual Desire Disorder (HSDD)
Interventions: DRUG: Placebo Vaginal Insert|DRUG: Prasterone 6.5 mg (0.50%) Vaginal Insert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vibrotactile Coordinated Reset for Parkinsons Patients Who Are on Dopaminergic Medication
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease, Idiopathic
Interventions: DEVICE: Vibrotactile Coordinated Reset
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Insulin Add-On Asia Regional Program - ST
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: Dapagliflozin|DRUG: Dapagliflozin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Home-based Exercise Programmes for Falls Prevention and Quality of Life in Older Adults
Status: UNKNOWN
Conditions: Accidental Falls
Interventions: BEHAVIORAL: T&E Home-based exercise programme|BEHAVIORAL: Otago|BEHAVIORAL: Helsana booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Metronomic Dosing, Etoposide, Cyclophosphamide, D0 Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Etoposide|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-arterial Sphenopalatine Ganglion Block for Patients With Refractory Headache
Status: WITHDRAWN
Conditions: Chronic Migraine|Cluster Headache|Trigeminal Neuralgia
Interventions: DRUG: Ketorolac|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positive Effects of Haematococcus Astaxanthin on Oxidative Stress and Lipid Profile in Overweight and Obese Adults
Status: UNKNOWN
Conditions: Healthy|Overweight|Obesity
Interventions: DIETARY_SUPPLEMENT: astaxanthin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose:
Clinical trial: A Study of Treatment With RO6864018 in Virologically Suppressed Participants With Chronic Hepatitis B Virus (HBV) Infection
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Entecavir|DRUG: Placebo|DRUG: RO6864018|DRUG: Tenofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Insitu Repair Versus Uterine Exeriorization During Cesarean Section
Status: COMPLETED
Conditions: Complications; Cesarean Section
Interventions: PROCEDURE: insitu repair|PROCEDURE: exteriorisation of the uterus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The SsRI/NIE Recombinant Antigen ELISA for the Follow up of Patients Infected by Strongyloides Stercoralis
Status: COMPLETED
Conditions: Strongyloides Stercoralis Infection
Interventions: DIAGNOSTIC_TEST: InBios Strongy Detect TM IgG ELISA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluate the Pharmacokinetics of a Combined Oral Contraceptive (COC) With and Without Obicetrapib
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: Obicetrapib|DRUG: Obicetrapib + Drospirenone / Ethinyl Estradiol (COC)|DRUG: Drospirenone / Ethinyl Estradiol (COC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Implant Using an Inverted Co-Axis at 12º Versus a Conventional Conical Implant
Status: RECRUITING
Conditions: Dental Implant Failed
Interventions: DEVICE: Immediate Implant Surgery|DEVICE: Immediate Implant Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Low Versus High Frequency Percutaneous Electrical Nerve Stimulation on Chronic Neck Pain Patients.
Status: COMPLETED
Conditions: Neck Pain|Chronic Pain|Myofascial Pain Syndrome
Interventions: PROCEDURE: Low frequency|PROCEDURE: High frequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Rapid Test to Prevent Hospital Transmission of Methicillin-Resistant Staphylococcus Aureus (MRSA)
Status: COMPLETED
Conditions: Methicillin Resistance|Staphylococcus Aureus|Staphylococcal Infection
Interventions: OTHER: Rapid MRSA PCR test for screening carriers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION