pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Wearable Monitoring Systems for Swallowing Function and Disorders
Status: COMPLETED
Conditions: Deglutition Disorders
Interventions: DEVICE: Tele-EaT Sensors|DEVICE: Conventional Sensors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Once-A-Day Pregabalin For Partial Seizures
Status: COMPLETED
Conditions: Partial Seizures|Epilepsies, Partial
Interventions: DRUG: pregabalin|DRUG: pregabalin|DRUG: pregabalin|DRUG: pregabalin|DRUG: pregabalin|DRUG: pregabalin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nebulized Bacteriophage Therapy in Cystic Fibrosis Patients With Chronic Pseudomonas Aeruginosa Pulmonary Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pseudomonas Aeruginosa Infection|Cystic Fibrosis
Interventions: DRUG: BX004-A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacological Interaction Between Doxazosin and Methylenedioxymethamphetamine (MDMA)
Status: COMPLETED
Conditions: Mood Disorder|Substance-Related Disorders|Amphetamine-Related Disorders
Interventions: DRUG: 3,4-Methylenedioxymethamphetamine|DRUG: Doxazosin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Electroacupuncture for the Management of Symptom Clusters in Cancer Patients and Survivors
Status: RECRUITING
Conditions: Cancer
Interventions: OTHER: Electroacupuncture|OTHER: Sham-Electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phenoxodiol Combined With Either Cisplatin or Paclitaxel in Patients With Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: cisplatin|DRUG: paclitaxel|DRUG: phenoxodiol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain in Single-visit and Multiple-visit Retreatment Cases
Status: COMPLETED
Conditions: Postoperative Pain|Root Canal Infection|Endodontic Disease
Interventions: OTHER: Single-Visit Retreatment|DRUG: Multiple-Visit-"Calcium Hydroxide"|DRUG: Multiple-Visit-"Corticosteroid Paste"|DRUG: Multiple-Visit-"Antibiotic Paste"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes of MP Persona vs. Persona Knee-PS
Status: ENROLLING_BY_INVITATION
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Zimmer MP Persona|DEVICE: Zimmer Persona Knee-PS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opioid Sparing Anesthesia in Patients With Liver Cirrhosis Undergoing Liver Resection
Status: COMPLETED
Conditions: Liver Cirrhosis
Interventions: DRUG: Opioid-based group (OB) (placebo/saline)|DRUG: Opioid sparing group (OS) (dexmedetomidine (PRECEDEX™ "dexmedetomidine hydrochloride" - Pfizer) and ketamine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Durvalumab+ Gemcitabine/Cisplatin (Neoadjuvant Treatment) and Durvalumab (Adjuvant Treatment) in Patients With MIBC
Status: ACTIVE_NOT_RECRUITING
Conditions: Muscle Invasive Bladder Cancer
Interventions: DRUG: Durvalumab|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resistance Exercise on Postprandial Hyperglycemia in Patients With B-thalassemia Exhibiting Resistance to Insulin
Status: COMPLETED
Conditions: Beta-Thalassemia|Insulin Resistance|PreDiabetes|Diabetes Mellitus, Type 2
Interventions: OTHER: Resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial of Lithium in Subjects With Progressive Supranuclear Palsy or Corticobasal Degeneration
Status: COMPLETED
Conditions: Progressive Supranuclear Palsy|Corticobasal Degeneration
Interventions: DRUG: Lithium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Child Characteristics, Neuromarkers, and Intervention Components Impacting Treatment Outcome: CCT, TF-CBT, TAU
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Cue-Centered Treatment (CCT)|BEHAVIORAL: Trauma-Focused CBT (TF-CBT)|BEHAVIORAL: Treatment as Usual|DEVICE: NIRScout
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Indirect Pulp Treatment of Young Permanent Molars Using Photo-Activated Oral Disinfection Versus Calcium Hydroxide
Status: COMPLETED
Conditions: Deep Caries
Interventions: DEVICE: photo-activated oral disinfection|DRUG: Calcium Hydroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liver Immunosuppression Free Trial
Status: TERMINATED
Conditions: Transplantation, Liver
Interventions: GENETIC: Biomarker|DRUG: Tacrolimus, cyclosporine and/or mycophenolic acid, mycophenolate mofetil or azathioprine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of a Pharmacist-led Multifaceted Intervention on Treatment Outcomes in Hypertensive Patients
Status: RECRUITING
Conditions: Hypertension
Interventions: BEHAVIORAL: pharmacist-led multifaceted intervention|BEHAVIORAL: conventional health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Vibrational-proprioceptive Resistance Exercise Training Versus Neuromuscular Electrical Stimulation Training in Elderly People With Muscle Weakness
Status: COMPLETED
Conditions: Muscle Weakness Condition|Therapy Effect
Interventions: DEVICE: Vibrational-proprioceptive Resistance Exercise Training|DEVICE: Neuromuscular Electrical Stimulation Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: African American Study of Kidney Disease and Hypertension ABPM Pilot Study
Status: COMPLETED
Conditions: Hypertensive Renal Disease
Interventions: BEHAVIORAL: USUAL - take your BP Meds as you usually do|BEHAVIORAL: HS DOSING|DRUG: ADD On Dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryoablation for Invasive Breast Carcinoma Following Neoadjuvant Therapy
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DEVICE: Visica 2™ Treatment System|PROCEDURE: Cryoablation|PROCEDURE: Surgical Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Tools Inserted Nasal Endotracheal Tube
Status: COMPLETED
Conditions: Intubation, Nasotracheal Intubation
Interventions: DEVICE: Macintosh Laryngoscope|DEVICE: Pentax Airway scope|DEVICE: Glidescope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Micronutrient Supplementation Before and During 1st Pregnancy to Improve Birth Outcomes (JiVitA-5)
Status: TERMINATED
Conditions: Birth Weight|Miscarriage|Small-for-gestational Age|Preterm Birth
Interventions: DIETARY_SUPPLEMENT: Multiple micronutrient supplement|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Alterations in Central Control of Shoulder Muscles in Office Workers With Non-specific Chronic Neck Pain
Status: COMPLETED
Conditions: Non-specific Chronic Neck Pain|Office Workers|Transcranial Magnetic Stimulation|Neuromuscular Control
Interventions: OTHER: 30-minute computer typing task|OTHER: 30-minute rest
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Do HMG CoA Reductase Inhibitors Affect Abeta Levels?
Status: COMPLETED
Conditions: Alzheimer's Disease|Aging
Interventions: DRUG: simvastatin|DRUG: pravastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Diagnosing Osteoradionecrosis in Patients With Head and Neck Cancer That Is Primary, Has Come Back, or Has Spread to Other Places in the Body
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: PROCEDURE: Dynamic Contrast-Enhanced Magnetic Resonance Imaging|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Immune Tolerance Mechanism Induced by IL-17-producing Regulatory T Cells in the Orthotopic Liver Transplant Recipients With Aspergillosis
Status: UNKNOWN
Conditions: Liver Transplantation|Aspergillus|Interleukin-17|Treg Cell|Immune Tolerance
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase II Non-Controlled, Open-Label, Efficacy, Safety, Pharmacokinetic, and Pharmacodynamic Study of Pacritinib in Myelofibrosis
Status: WITHDRAWN
Conditions: Primary Myelofibrosis
Interventions: BIOLOGICAL: Pacritinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Safety and Efficacy BMMNC in Cerebellar Ataxia
Status: UNKNOWN
Conditions: Cerebellar Ataxia
Interventions: BIOLOGICAL: Intravenous transfer of of Bone Marrow derived Mono Nuclear Stem Cell (BMMNCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Gastric Plication Compared With Laparoscopic Sleeve Gastrectomy
Status: UNKNOWN
Conditions: Morbid Obesity
Interventions: PROCEDURE: Laparoscopy surgery for morbid obesity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lee Silverman Voice Treatment Versus Standard Speech Therapy Versus Control in Hypophonia Rehabilitation in MS
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: OTHER: Lee Silverman Voice Therapy|OTHER: Conventional Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Moderato System in Patients With Hypertension
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension, Resistant to Conventional Therapy|Atrioventricular Block
Interventions: DEVICE: BackBeat Moderato System|DEVICE: BackBeat Moderato Sytsem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Early Intensive Leg Exercise to Improve Walking in Children With Diplegia
Status: RECRUITING
Conditions: Spastic Diplegia|Periventricular Leukomalacia
Interventions: BEHAVIORAL: Intensive exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of SGLT2 Inhibitor in Diabetic Patients With Coronary Artery Disease
Status: UNKNOWN
Conditions: Coronary Disease With Diabetes Mellitus
Interventions: DRUG: Dapagliflozin 10 MG [Farxiga]|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Acetyl Hexapeptide-8 and the Cosmetic Appearance of Oily Skin
Status: COMPLETED
Conditions: Oily Skin
Interventions: OTHER: Acetyl Hexapeptide-8|OTHER: Placebo vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of The Femoral Popliteal Artery Treated With LEGFLOW OTW
Status: UNKNOWN
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Paclitaxel Releasing Peripheral Balloon Dilatation Catheter|DEVICE: Peripheral Balloon Dilatation Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tenofovir Alafenamide for Treatment of Symptoms and Neuroprotection in Relapsing Remitting Multiple Sclerosis
Status: WITHDRAWN
Conditions: Multiple Sclerosis, Relapsing-Remitting|Fatigue
Interventions: DRUG: TENOFOVIR ALAFENAMIDE FUMARATE 25 Mg ORAL TABLET [VEMLIDY]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgetic Effect of Preoperative Pregabalin in Patients Undergoing Nephrectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety, Tolerability, and PK of SZEY-2108 Administered Intravenously to HVs in SAD and MAD Cohorts
Status: RECRUITING
Conditions: Infections
Interventions: DRUG: SZEY-2108 for injetion|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing the Care Transitions Intervention With Peer Support to Reduce Disparities
Status: UNKNOWN
Conditions: Hospital Readmissions
Interventions: BEHAVIORAL: Care Transitions Intervention|BEHAVIORAL: Care Transitions Intervention and Peer Support|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Biomarkers in Immunotherapy of Melanoma
Status: RECRUITING
Conditions: Metastatic Melanoma|Immune Checkpoints Inhibitors|Gastrointestinal Microbiome (Bacterial and Viral)|Exosomal mRNA Expression of PD-L1 and IFNγ
Interventions: DRUG: Immune checkpoint inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Prednisone-sparing Effect of Anti-IL-5 Antibody (SB-240563)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: SB-240563 (Mepolizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study to Re-assess and Re-confirm Data Previously Recorded About the Incidence and Severity of Acute Abdominal "Pancreatitis" Episodes in Lipoprotein Lipase Deficient (LPLD) Subjects Previously Enrolled on AMT Clinical Studies
Status: UNKNOWN
Conditions: Lipoprotein Lipase Deficiency
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Addressing Barriers to Anti-hypertensive Medication Adherence Among PLWH Who Have Achieved Viral Suppression
Status: RECRUITING
Conditions: Hypertension|HIV-1-infection
Interventions: BEHAVIORAL: Hypertension control through education and monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Immunogenicity and Safety of Two Dose Levels of OVX836 Influenza Vaccine as a Booster on Participants Previously Administered With OVX836
Status: NOT_YET_RECRUITING
Conditions: Vaccine-Preventable Diseases|Influenza
Interventions: BIOLOGICAL: OVX836 shot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of TBio-4101 (TIL) and Pembrolizumab in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Breast Cancer|Colorectal Cancer|Uveal Melanoma|Cutaneous Melanoma|Non-Small Cell Lung Cancer|Head and Neck Squamous Cell Carcinoma
Interventions: BIOLOGICAL: TBio-4101|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Pain After Inguinal Hernia Repair, the ONSTEP Technique Versus the Laparoscopic Approach
Status: COMPLETED
Conditions: Hernia, Inguinal|Chronic Pain
Interventions: PROCEDURE: Onstep|PROCEDURE: Laparoscopic repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Engaging Fathers in Home Visitation
Status: COMPLETED
Conditions: Interparental Conflict|Parenting|Parent-child Relations|Fathers
Interventions: BEHAVIORAL: Family Foundations coparenting program|BEHAVIORAL: Home visiting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Emdogain® on Soft Tissue Wound Healing
Status: COMPLETED
Conditions: Periodontal Inflammation|Crown Lengthening
Interventions: DEVICE: PrefGel® + Emdogain®|DEVICE: PrefGel®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Global Mental Health of Urban Mothers
Status: NOT_YET_RECRUITING
Conditions: Perinatal Depression|COVID19|Anxiety|PTSD|Pregnancy Related
Interventions: BEHAVIORAL: Web-based psychosocial peer-to-peer support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Virtual Rehabilitation and PNF in the Recovery of the Motor Function Post Stroke
Status: COMPLETED
Conditions: Stroke|Cerebrovascular Disorders
Interventions: OTHER: Virtual Rehabilitation|OTHER: PNF Method|OTHER: Virtual Rehabilitation and PNF Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Ixabepilone (BMS-247550) by Every-3-week Dosing Regimen in Patients With Metastatic Breast Cancer Previously Treated With an Anthracycline and Who Are Taxane Resistant
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avelumab in Refractory Testicular Germ Cell Cancer.
Status: COMPLETED
Conditions: Testicular Neoplasms|Neoplasms, Germ Cell and Embryonal|Neoplasms|Testicular Diseases|Gonadal Disorders|Antineoplastic Agents|Molecular Mechanisms of Pharmacological Action
Interventions: DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Drug Interaction of ASP015K and Midazolam
Status: COMPLETED
Conditions: Healthy|Pharmacokinetics of ASP015K and Midazolam
Interventions: DRUG: ASP015K|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Bevacizumab (Avastin®) + Erlotinib as First-line Therapy for Stage IIIB/IV or Recurrent, Non-squamous Cell Lung Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Bevacizumab and Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Nalbuphine on Emergence Agitation
Status: COMPLETED
Conditions: Postoperative Complications
Interventions: DRUG: IV nalbuphine 0.1 mg/kg with induction of anesthesia.|DRUG: IV nalbuphine 0.1 mg/kg at the end of surgery.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Colchicine Treatment for Chronic Shoulder Pain Related to Calcific Tendonitis
Status: UNKNOWN
Conditions: Calcific Tendonitis
Interventions: DRUG: Colchicine|DRUG: lactose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tailored PCA Based on Preoperative Pain Sensitivity
Status: COMPLETED
Conditions: Analgesia, Patient-Controlled
Interventions: OTHER: Tailored regimen of IV PCA according to pain sensitivity|OTHER: Regimen of IV PCA without considering pain sensitivity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Ascorbic Acid in Women Receiving Adjuvant or Neo-Adjuvant Chemotherapy for Early Stage Breast Cancer
Status: WITHDRAWN
Conditions: Fatigue
Interventions: DRUG: Ascorbic Acid|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pegylated Interferon (PEG-IFN) Alfa-2b and Low Dose Ribavirin for the Treatment of Chronic Hepatitis C Patients With Genotype 1 High Viral Load and Low Body Weight (Study P05172)(COMPLETED)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: BIOLOGICAL: Pegylated Interferon alfa-2b|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of Antidepressant Treatment in Adolescents With Major Depression (The Adolescents MDD Study)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Fluoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder|Insomnia|Cardiovascular Diseases|Metabolic Disease
Interventions: BEHAVIORAL: Behavioral Sleep Education Intervention|BEHAVIORAL: General Sleep Education Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of AGN-214868 in Patients With Idiopathic Overactive Bladder and Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: AGN-214868|DRUG: AGN-214868 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Real-tiMe ContInuous gLucosE moNitoriNg With Self-monitorIng of Blood Glucose in Young AduLts With Type 1 diabeteS
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Real-time continuous glucose monitoring|DEVICE: Self-monitoring of blood glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Psychotropic Drug Use in the Elderly Living in Nursing Homes and the Influence of a Structured Drug Review
Status: COMPLETED
Conditions: Cognitive Symptom|Depression|Anxiety|Neuropsychiatric Syndrome|Quality of Life|Activity of Daily Living|Physical Health|Drug Use
Interventions: OTHER: Drug reviews with NorGeP-NH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acupuncture for Primary Sjögren Syndrome
Status: UNKNOWN
Conditions: Sjogren's Syndrome
Interventions: DEVICE: acupuncture group|DEVICE: Sham Acupuncture group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Fixed Dose Versus Serum Level-Based Titration Regimen of Vitamin D Supplementation in Dialysis Patients
Status: COMPLETED
Conditions: Vitamin D Deficiency|End Stage Renal Disease
Interventions: OTHER: ergocalciferol supplementation|OTHER: dialysis techniques|OTHER: sunlight exposure time
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
Status: RECRUITING
Conditions: Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|HER2-Negative Breast Carcinoma|Hormone Receptor-Positive Breast Carcinoma|Localized Breast Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Cyclophosphamide|DRUG: Doxorubicin|BIOLOGICAL: Durvalumab|OTHER: Genetic Testing|PROCEDURE: Mammography|DRUG: Paclitaxel|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Efficacy and Safety Study of Intramuscular Injection of Human Placenta-Derived Cells (PDA-002) in Subjects With Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Nephropathies|Peripheral Nervous System Diseases
Interventions: BIOLOGICAL: PDA-002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Use of the MMF07 Foot Massager and Heat Therapy Treatments for Restless Leg Syndrome
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DEVICE: MMF07 Foot Massager|DEVICE: Heat Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect Of Curcuma Xanthorrhiza and Vitamin D3 Supplementation in SLE Patients With Hypovitamin D
Status: COMPLETED
Conditions: SLE
Interventions: DIETARY_SUPPLEMENT: "Cholecalciferol" and "C. Xanthorrhiza"|DIETARY_SUPPLEMENT: "Cholecalciferol" and "placebo"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Soy Protein and Breast Cancer Risk Reduction
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DIETARY_SUPPLEMENT: soy milk|DIETARY_SUPPLEMENT: cow's milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Body Position and Recruiting Maneuver on Lung Aeration Assessed Through Ultrasound in Patients Intubated for Acute Respiratory Failure Related to Novel Coronavirus 19 Disease
Status: COMPLETED
Conditions: Acute Respiratory Failure
Interventions: OTHER: lung ultrasound assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SmartQuit Program for Smoking Cessation
Status: COMPLETED
Conditions: Cigarette Smoking-Related Carcinoma|Tobacco-Related Carcinoma
Interventions: BEHAVIORAL: SmartQuit Smoking and Tobacco Cessation Program|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The PK/PD, Efficacy, Safety and Tolerability Study of SHR3824 in Combination With Metformin in Type 2 Diabetes Mellitus Patients
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: SHR3824|DRUG: Placebo|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acetazolamide Facilitates Ventilator Weaning
Status: UNKNOWN
Conditions: Ventilator Weaning|Alkalosis, Metabolic
Interventions: DRUG: acetazolamide|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First In Human Study Of Increasing Oral Doses Of PF-04634817
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-04634817 Placebo|DRUG: PF-04634817|DRUG: PF-04634817|DRUG: PF-04634817|DRUG: PF-04634817|DRUG: PF-04634817|DRUG: PF-04634817|DRUG: PF-04634817|DRUG: PF-04634817|DRUG: PF-04634817|DRUG: PF-04634817 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Evaluating Low Dose G-FLIP Plus Mitomycin C for Stage IV Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: G-GLIP plus Mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avenir Complete Post-Market Clinical Follow-Up Study
Status: RECRUITING
Conditions: Osteoarthritis, Hip|Avascular Necrosis of Hip|Avascular Necrosis of the Femoral Head|Post-traumatic; Arthrosis
Interventions: DEVICE: Avenir Complete Femoral Stem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TOP-TRIAL Safety of Not Flushing Non-used PORT-A-CATH® in Cancer Patients
Status: TERMINATED
Conditions: Adjuvant Chemotherapy|Solid Tumours|Port-A-Cath
Interventions: PROCEDURE: evaluation of PORT-A-CATH®|DRUG: blocking with Medunasal®-Heparinblock|DRUG: restoration of PORT-A-CATH® with Alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combined Endoscopic Epicardial and Percutaneous Endocardial Ablation Versus Repeated Catheter Ablation in Persistent and Longstanding Persistent Atrial Fibrillation
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation|Persistent and Longstanding Persistent Atrial Fibrillation
Interventions: DEVICE: AtriCure Bipolar System|DEVICE: Standard Endocardial Ablation with Catheter|DEVICE: AtriClip® PRO LAA Exclusion System|DEVICE: Endocardial Ablation with Catheter|DEVICE: Repeated Endocardial ablation(s)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Native Tissue Repair With Surgical Pelvic Organ Pessary - an RCT
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse
Interventions: OTHER: Surgical Pelvic Organ Pessary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ILUMIEN IV: OPTIMAL Percutaneous Coronary Intervention (PCI)
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Stenosis|Atherosclerosis|STEMI|STEMI - ST Elevation Myocardial Infarction|NSTEMI - Non-ST Segment Elevation Myocardial Infarction (MI)
Interventions: DEVICE: Coronary PCI guided by OCT|DEVICE: Coronary PCI guided by Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COPD on Primary Care Treatment (COOPT)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Lung Diseases, Obstructive|Bronchitis, Chronic
Interventions: DRUG: N-acetylcysteine|DRUG: fluticasone propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID and Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Brinzolamide 1%/brimonidine tartrate 0.2% ophthalmic suspension|DRUG: Brinzolamide 1% ophthalmic suspension|DRUG: Brimonidine tartrate 0.2% ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SU5416 Plus Hormone Therapy and Radiation Therapy in Treating Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: bicalutamide|DRUG: flutamide|DRUG: goserelin acetate|DRUG: leuprolide acetate|DRUG: SU5416|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Rituximab Treatment in Addition to Standard Care for Newly Presenting Thrombotic Thrombocytopenic Purpura
Status: WITHDRAWN
Conditions: Thrombotic Thrombocytopenic Purpura
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LIM-0705 in Male Subjects With Impaired Glucose Tolerance
Status: WITHDRAWN
Conditions: Impaired Glucose Tolerance
Interventions: DRUG: LIM-0705|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic, Safety, and Tolerability Study of Intranasally Administered Esketamine in Elderly Japanese, and Healthy Younger Adult Japanese Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Esketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment With Dinutuximab, Sargramostim (GM-CSF), and Isotretinoin in Combination With Irinotecan and Temozolomide After Intensive Therapy for People With High-Risk Neuroblastoma (NBL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Ganglioneuroblastoma, Nodular|Neuroblastoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|BIOLOGICAL: Dinutuximab|PROCEDURE: FDG-Positron Emission Tomography|RADIATION: Iobenguane I-123|DRUG: Irinotecan|DRUG: Isotretinoin|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Multigated Acquisition Scan|BIOLOGICAL: Sargramostim|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Innovative Biomarkers in de Novo Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson's Disease|Healthy Controls Group - Age and Sex-matched
Interventions: PROCEDURE: Brain MRI|PROCEDURE: TMS-EEG|BEHAVIORAL: Behavioral and cognitive battery|OTHER: Clinical evaluation and clinical scales
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Assess Effectiveness and Safety of Deucravacitinib Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Deucravacitinib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Co-administration of Dexmedetomidine in Carotid Endarterectomy (CEA)
Status: COMPLETED
Conditions: Carotid Stenosis
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gefitinib and PEG-Interferon Alfa-2b in Treating Patients With Unresectable or Metastatic Kidney Cancer
Status: TERMINATED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: PEG-interferon alfa-2b|DRUG: gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplant, Chemotherapy, and Biological Therapy in Treating Patients With High-Risk or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: CMV pp65 peptide|BIOLOGICAL: hTERT I540/R572Y/D988Y multipeptide vaccine|BIOLOGICAL: pneumococcal polyvalent vaccine|BIOLOGICAL: survivin Sur1M2 peptide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of MEDI0382 on Energy Balance in Overweight and Obese Participants With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type II|Obesity
Interventions: DRUG: MEDI0382|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Oral L-Glutamine in Head and Neck Cancer Patients During Radiotherapy
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DIETARY_SUPPLEMENT: oral glutamine|DIETARY_SUPPLEMENT: placebo|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety of Primary and Booster Vaccination With DTPa-HBV-IPV/Hib Vaccine
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: DTPa-HBV-IPV/Hib vaccine|BIOLOGICAL: DTPa-IPV/Hib vaccine|BIOLOGICAL: EngerixTM-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Rehabilitation Exercise Using Digital Healthcare System in Patients With Rotator Cuff Repair
Status: UNKNOWN
Conditions: Rotator Cuff Tears
Interventions: DEVICE: Rehabilitation using Digital Healthcare System (Uincare Homeplus)|OTHER: Conventional Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of BGF and GFF on Specific Image Based Airway Volumes and Resistance in Subjects With Moderate to Severe COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: COMBINATION_PRODUCT: BGF|COMBINATION_PRODUCT: GFF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pecha Kucha Method Effects on Posttraumatic Growth and Psychological Resilience
Status: RECRUITING
Conditions: Posttraumatic Growth|Psychological Resilience|Breast Cancer Patients
Interventions: OTHER: Education with pecha kucha method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Masitinib in Patients With Gastrointestinal Stromal Tumour After Progression With Imatinib
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Masitinib|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Heart Failure Using Human Umbilical Cord Mesenchymal Stem Cells(hUC-MSC)
Status: UNKNOWN
Conditions: Myocardial Ischemia|Ventricular Dysfunction, Left
Interventions: BIOLOGICAL: Allogeneic Human Umbilical Cord Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fibromyalgia and Naltrexone: The FINAL Study
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Naltrexone Pill|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Glutathione Supplementation on the Levels of Blood Glutathione
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DRUG: Glutathione supplementation|DRUG: Gluthathione peroxidases|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of HIIT, MICT in Patients With Myocardial Infarction
Status: UNKNOWN
Conditions: Myocardial Infarction|Cardiopulmonary Disease|Training Group, Sensitivity
Interventions: BEHAVIORAL: High Intensity Interval Training(HIIT）|BEHAVIORAL: Moderate Intensity Continuous Training(MICT）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The SLIM Study: Sling and Botox® Injection for Mixed Urinary Incontinence
Status: COMPLETED
Conditions: Mixed Urinary Incontinence|Stress Urinary Incontinence|Urgency Incontinence
Interventions: DRUG: OnabotulinumtoxinA (Botox ®) Injections|DRUG: Saline Injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immune-Pineal Axis Function in Chronic Tension-Type Headache
Status: COMPLETED
Conditions: Chronic Tension-Type Headache
Interventions: DEVICE: Electroacupuncture|DEVICE: Placebo Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Response of Cardiometabolic Biomarkers and Gut Microbiota to Walnut Consumption
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Walnuts|DIETARY_SUPPLEMENT: No-nut diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Determining the Impact of a Medication Delivery Unit on Medication Adherence of Adults With Common Cardiac Conditions
Status: TERMINATED
Conditions: Medication Adherence|Medication Nonadherence|Adverse Reaction to Drug
Interventions: DEVICE: Computerized medication delivery unit|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Quetiapine in Treating Affective Symptoms of Patients With First-episode psychosis-a Pilot Study
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Seroquel®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prolonged Minimal Enteral Nutrition Versus Slowly Advancing Enteral Nutrition in Very Low Birth Weight Infants:
Status: COMPLETED
Conditions: Enteral Nutrition|Born Very Premature|Infant, Very Low Birth Weight
Interventions: DIETARY_SUPPLEMENT: nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pilot Test of ACTOS in Multiple Sclerosis: Safety and Tolerability
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: ACTOS (Pioglitazone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: INFUSE ® Bone Graft/CORNERSTONE-SR® Allograft Ring/ATLANTIS® Anterior Cervical Plate System Pivotal Trial
Status: TERMINATED
Conditions: Degenerative Cervical Disc Disease
Interventions: DEVICE: INFUSE™ Bone Graft/CORNERSTONE-SR™ /ATLANTIS™|DEVICE: Autogenous bone/CORNERSTONE-SR™ /ATLANTIS™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate a Dose of Telotristat Etiprate in Male and Female With Mild, Moderate and Severe Hepatic Insufficiency and Matched Healthy Subjects
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: telotristat etiprate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Indirect vs. Direct Decompression for Treatment of Central Stenosis: RCT
Status: WITHDRAWN
Conditions: Patients With Spinal Stenosis Indicated for LLIF
Interventions: PROCEDURE: One-level lateral lumbar interbody fusion with Indirect Decompression|PROCEDURE: One-level lateral lumbar interbody fusion with Direct Decompression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT