pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The University of Miami Adapt (UAdapt) Trial
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: FTLEAD|DRUG: Ultra-Short-Term Androgen Deprivation Therapy with Relugolix|RADIATION: HypoLEAD|DRUG: ADT Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ventilation Using a Bag Valve Mask With Supplemental External Handle
Status: COMPLETED
Conditions: Apnea
Interventions: DEVICE: Modified Ambu Spur II bag valve mask|DEVICE: Conventional Ambu Spur II bag valve mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mycophenolate Mofetil (MMF) Versus Intravenous CTX Pulses in the Treatment of Adult Severe HSPN
Status: COMPLETED
Conditions: Henoch-Schoenlein Purpura|Nephritis
Interventions: DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing if Cryoneurolysis Improves Prehabilitation and Decreases Pain After Surgery With Less Opioid Use in TKA Patients
Status: WITHDRAWN
Conditions: Arthropathy of Knee|Pain, Joint|Arthritis Knee|Opioid Use
Interventions: DEVICE: iovera°
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Learning Super Resolution Reconstruction for Fast and Motion Robust T2-weighted Prostate MRI
Status: COMPLETED
Conditions: Prostate Cancer|Multiparametric MRI
Interventions: DEVICE: Deep learning based reconstruction of T2-TSE sequence
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ALRN-6924 in Patients With Advanced Solid Tumors or Lymphomas
Status: COMPLETED
Conditions: Solid Tumor|Lymphoma|Peripheral T-Cell Lymphoma
Interventions: DRUG: ALRN-6924
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study to Compare Two Rosacea Treatment Regimens
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: doxycycline|DRUG: doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hypertension and Arrhythmias in CLL Patients Treated With BTK Inhibitors
Status: ENROLLING_BY_INVITATION
Conditions: Chronic Lymphocytic Leukemia|Atrial Fibrillation|Hypertension|Cardiotoxicity
Interventions: OTHER: no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Comparison Between the PVAM and CPVI for the Patients of PAF
Status: COMPLETED
Conditions: Atrial Fibrillation|Pulmonary Vein Isolation
Interventions: PROCEDURE: pulmonary vein antrum modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of Visual Healing® in Psilocybin-assisted Therapy for Alcohol Use Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: Psilocybin plus Visual Healing Set and Setting|DRUG: Psilocybin plus Standard Set and Setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy (PDT) Trial for Palliation of Cholangiocarcinoma
Status: TERMINATED
Conditions: Cholangiocarcinoma
Interventions: PROCEDURE: ERCP and Photodynamic Therapy|PROCEDURE: ERCP only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MV-NIS or Investigator's Choice Chemotherapy in Treating Patients With Ovarian, Fallopian, or Peritoneal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Fallopian Tube Carcinosarcoma|Fallopian Tube Clear Cell Adenocarcinoma|Fallopian Tube Endometrioid Adenocarcinoma|Fallopian Tube Mucinous Adenocarcinoma|Fallopian Tube Serous Adenocarcinoma|Fallopian Tube Transitional Cell Carcinoma|Fallopian Tube Undifferentiated Carcinoma|Ovarian Carcinosarcoma|Ovarian Clear Cell Adenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mucinous Adenocarcinoma|Ovarian Seromucinous Carcinoma|Ovarian Serous Adenocarcinoma|Ovarian Transitional Cell Carcinoma|Ovarian Undifferentiated Carcinoma|Platinum-Resistant Fallopian Tube Carcinoma|Platinum-Resistant Ovarian Carcinoma|Platinum-Resistant Primary Peritoneal Carcinoma|Primary Peritoneal Carcinosarcoma|Primary Peritoneal Clear Cell Adenocarcinoma|Primary Peritoneal Endometrioid Adenocarcinoma|Primary Peritoneal Serous Adenocarcinoma|Primary Peritoneal Transitional Cell Carcinoma|Primary Peritoneal Undifferentiated Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Gemcitabine Hydrochloride|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Oncolytic Measles Virus Encoding Thyroidal Sodium Iodide Symporter|DRUG: Paclitaxel|DRUG: Pegylated Liposomal Doxorubicin Hydrochloride|OTHER: Quality-of-Life Assessment|DRUG: Topotecan Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Clinical Performances of a Point of Care Analyzer Enabling Pre-transfusion ABOD Group Ultimate Verification at the Patient Bedside
Status: UNKNOWN
Conditions: Blood Transfusion Complication
Interventions: DEVICE: ABODpoct device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lipoproteins and ImmunoMetabolism
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Metabolic Syndrome|Metabolism Disorder|Inflammation|Immune System and Related Disorders
Interventions: DIETARY_SUPPLEMENT: Lipid Emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Can Extracorporeal Shock Wave Therapy Be Effective in Temporomandibular Joint Disease
Status: COMPLETED
Conditions: Temporomandibular Joint Disc Displacement, With Reduction|Extracorporeal Shock Wave Therapy
Interventions: DEVICE: Extracorporeal Shock Wave Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Hemoperfusion or Plasma Exchange Compared to Standard Medical Therapy in Patients With Acute on Chronic Liver Failure
Status: UNKNOWN
Conditions: Acute-On-Chronic Liver Failure
Interventions: DRUG: Haemoperfusion|DRUG: Standard Medical Treatment|OTHER: Plasma Exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutrient Nutritional Advise for Low Back Pain Patients Seeking Chiropractic Care
Status: COMPLETED
Conditions: Low Back Pain|Nutrition Poor
Interventions: DIETARY_SUPPLEMENT: Combination: Nutrition AND Chiropractic Adjustment|OTHER: Chiropractic Adjustment: Spinal Manipulation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Statin Therapy in Patients With Early Stage ADPKD
Status: ACTIVE_NOT_RECRUITING
Conditions: ADPKD|Autosomal Dominant Polycystic Kidney
Interventions: DRUG: Pravastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of a Compound Glutamine Capsule in the Primary Prevention of Chemotherapy-induced Mucositis
Status: UNKNOWN
Conditions: Mucositis|Chemotherapeutic Toxicity
Interventions: DRUG: a compound glutamine capsule/a compound glutamine capsule simulated placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Somatostatin on ADPKD Heart
Status: COMPLETED
Conditions: Autosomal Dominant Polycystic Kidney Disease|Glomerular Filtration Rate > 40 ml/Min
Interventions: DRUG: Octeotride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Patient Safety by Supporting Older Adults in Managing Sleep Problems.
Status: NOT_YET_RECRUITING
Conditions: Benzodiazepines Deprescribing|Sleep Problems
Interventions: OTHER: Specific tapering plan for sleep medication, educational and cognitive behavioural therapy elements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimize Low Back Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Low Back Pain|Chronic Pain
Interventions: BEHAVIORAL: Physical Therapy|BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Platinum Doublets and Hypofractionated Radiotherapy in NSCLC
Status: WITHDRAWN
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Cisplatin|RADIATION: hypofractionated radiotherapy|DRUG: Pemetrexed|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open and Laparoscopic Total Extraperitoneal Repair Under Spinal Anesthesia Versus General Anesthesia
Status: COMPLETED
Conditions: Pain, Postoperative|Postoperative Complications|Inguinal Hernia
Interventions: PROCEDURE: Spinal anesthesia (with nerve block)|PROCEDURE: General anesthesia (GA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Linggui Yangyuan Paste in Patients With Male Infertility
Status: NOT_YET_RECRUITING
Conditions: Male Infertility|Asthenozoospermia|Oligoasthenozoospermia
Interventions: DRUG: LGYY|DRUG: LGYY mimetic|DRUG: WZYZ|DRUG: WZYZ mimetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of CLDN18.2 PET/CT for Noninvasive Diagnosis of Gastric and Pancreatic Cancer
Status: RECRUITING
Conditions: Positron Emission Tomography|Pancreatic Neoplasms|Igestive System Neoplasms
Interventions: RADIATION: [18F]F-H3RESCA-3A12及[68Ga]Ga-NOTA-3A12
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Look at How Safe NNC0268-0965 is in Healthy People and People With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Healthy Volunteers
Interventions: DRUG: NNC0268-0965|DRUG: Placebo|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Middle Meningeal Artery Embolization for Chronic Subdural Hematoma
Status: RECRUITING
Conditions: Chronic Subdural Hematoma
Interventions: PROCEDURE: Middle Meningeal Artery Embolization with polyvinyl alcohol particles (PVA)|PROCEDURE: Drainage of Subdural Hematoma
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Thoracic Epidural Analgesia Influence Urinary Micturition by Patients Undergoing Thoracic Surgery?
Status: COMPLETED
Conditions: Thoracotomy|Sternotomy
Interventions: PROCEDURE: Assessment of urinary micturition after thoracotomy|OTHER: International Prostate Symptom Score
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Cardiac Effects of a Novel Food Ingredient in Healthy Male Subjects
Status: COMPLETED
Conditions: Cardiovascular Abnormalities
Interventions: OTHER: R,R-monatin|OTHER: Moxifloxacin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: An Efficacy Study of MORAb-009 in Subjects With Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: MORAb-009|DRUG: Placebo|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Antihypertensive Effect of Remote Ischemic Conditioning (RIC-HTN).
Status: COMPLETED
Conditions: Hypertension,Essential|Prehypertension
Interventions: DEVICE: Remote ischemic conditioning (RIC)|DEVICE: Sham remote ischemic conditioning (Sham-RIC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Acute Stress on Motor Learning and Motor Imagery Ability in Young Population
Status: COMPLETED
Conditions: Stress, Psychological
Interventions: OTHER: Stress group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Blood Brain Barrier Differences in Patients With Brain Tumors Undergoing Surgery
Status: COMPLETED
Conditions: Central Nervous System Neoplasm|Localized Brain Neoplasm|Metastatic Malignant Neoplasm in the Brain|Recurrent Brain Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Physiological Variables and Detection of Blood Loss in Healthy Adults With Different Subject Positioning by the CM-1500
Status: COMPLETED
Conditions: Fluid Loss|Blood Loss
Interventions: DEVICE: Whole blood donation supine|DEVICE: Whole blood donation reclined
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Raltegravir on Endothelial Function in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infection|Inflammation|Cardiovascular Disease|HIV Infections
Interventions: DRUG: raltegravir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in Subjects With Active Behçet's Disease
Status: COMPLETED
Conditions: Behçet's Syndrome
Interventions: DRUG: Apremilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness and Compassion-based Programs on Food Behavior of Patients With Weight Regain After Bariatric Surgery
Status: UNKNOWN
Conditions: Obesity
Interventions: BEHAVIORAL: Mindfulness-Based Health Promotion + Treatment as usual|BEHAVIORAL: Attachment-based compassion therapy + Treatment as usual|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparison of the Effect of Two Types of Whole Body Vibration on Fibromyalgia. A Randomized Controlled Trial.
Status: UNKNOWN
Conditions: Fibromyalgia
Interventions: DEVICE: Vertical whole body vibration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Association of Hormonal Intake and Demographic Factors With Breast Cancer Risk. An Egyptian Case-controlled Study
Status: UNKNOWN
Conditions: Observational Study
Interventions: DRUG: Dydrogesterone Tablets, Norethisterone acetate, Ethinyl estradiol, Drospirenone and ethinyl estradiol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of DNS Exercises Training on Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: OTHER: dynamic neuromuscular stabilization training|OTHER: balance exercises plus diaphragmatic breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Written Exposure Therapy to Improve Recovery Among Sexual Assault Survivors
Status: NOT_YET_RECRUITING
Conditions: Post-traumatic Stress Disorder
Interventions: BEHAVIORAL: Written Exposure Therapy|BEHAVIORAL: Unemotional Writing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: It is a Prospective Study Aiming to Identify Incidence and Prevalence of Cardiovascular Diseases, Changes in Physical Activity, Dietary Habits and Anxiety Depression Levels Through a Period of Time in the Naval Personnel (PrOspeCtive HEllenic NAval PersoNnel StUdy in CardiovaScular Diseases)
Status: RECRUITING
Conditions: Cardiovascular Diseases|Risk Factor, Cardiovascular
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: OTX-14-003: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Ocular Inflammation and Pain After Cataract Surgery
Status: COMPLETED
Conditions: Post-Surgical Ocular Pain|Post-Surgical Ocular Inflammation
Interventions: DRUG: Dexamethasone|PROCEDURE: Placebo Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Ischaemic Preconditioning in Childhood Cancer
Status: COMPLETED
Conditions: Cardiotoxicity
Interventions: PROCEDURE: Remote Ischaemic Preconditioning|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Pregabalin on the Postoperative Analgesia in RFA of Focal Lesions in the Liver
Status: UNKNOWN
Conditions: Hepatocellular Cancer
Interventions: DRUG: Pregabalin 150mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Meta-analysis of Fish Oil Supplementation and Cardiovascular Outcomes in Diabetes
Status: UNKNOWN
Conditions: Type2 Diabetes|Heart Failure|Myocardial Infarction|Stroke|Arrhythmia|Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: fish oil supplement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Weekly Administration of (bi-)Daily Oral Docetaxel in Combination With Ritonavir
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: ModraDoc001 10mg capsules|DRUG: ModraDoc003 10mg tablets and ModraDoc004 10/50 mg|DRUG: ModraDoc006 10 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and Chemotherapy in Treatment of Pancreatic Adenocarcinoma
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: RADIATION: High Dose Rate Brachytherapy (HDR) Intraoperative Radiation Therapy (IORT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Neural Mechanism of Stellate Ganglion Block in the Treatment of Anxiety. Disorder.
Status: NOT_YET_RECRUITING
Conditions: Anxiety Disorders|Stellate Ganglion Block
Interventions: OTHER: Stellate Ganglion Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Nexium Versus Secretol in the Healing and Controlling of Symptoms in GERD Patients With Severe EE.
Status: UNKNOWN
Conditions: Gastroesophageal Reflux Disease (GERD)|Heartburn|Indigestion
Interventions: DRUG: Secretol|DRUG: Nexium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LEVANT I, The Lutonix Paclitaxel-Coated Balloon for the Prevention of Femoropopliteal Restenosis
Status: COMPLETED
Conditions: Atherosclerosis|Vascular Disease|Arteriosclerosis
Interventions: DEVICE: Lutonix Catheter|DEVICE: Standard uncoated Balloon Angioplasty Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Open Label, Three-Treatment, Three-Period, Six-Sequence Crossover Study To Compare Safety and Pharmacokinetic Properties of CJ-30044 and Bepotastine Besilate and To Investigate Food-effect on Pharmacokinetics of CJ-30044 in Healthy Adult Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CJ-30044|DRUG: TALION TAB. 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Second-line Cabozantinib and Atezolizumab in Patients With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Esophageal Cancer|Metastatic Cancer|Squamous Cell Carcinoma
Interventions: DRUG: Cabozantinib 40 MG|DRUG: Atezolizumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Sorafenib Dosed Continuously With Cyclophosphamide and Doxorubicin
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Nexavar (Sorafenib, BAY43-9006)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Dose Effectiveness of Vitamin D Supplementation During Pregnancy- a Dose Comparison Trial
Status: COMPLETED
Conditions: Pregnancy
Interventions: DRUG: Vitamin D supplement|DRUG: Vitamin D supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population
Status: RECRUITING
Conditions: Cataract|Surgery|Compliance, Patient|Compliance, Medication|Satisfaction, Patient
Interventions: DRUG: Dropless Regimen|DRUG: Standard Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Transplantation of EPCs to Treat Idiopathic Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Idiopathic Pulmonary Arterial Hypertension
Interventions: PROCEDURE: Transplantation of autologous endothelial progenitor cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Lutein Supplementation on Cognition and MPOD in Multiple Sclerosis Patients-
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: DIETARY_SUPPLEMENT: Lutein|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cetuximab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of SHR-1210 in Combination With Carboplatin+Paclitaxel-albumin in Subjects With Resectable NSCLC
Status: UNKNOWN
Conditions: Lung Cancer Stage II|PD-1 Antibody|Non-small Cell Lung Cancer
Interventions: DRUG: SHR-1210|DRUG: Carboplatin and Paclitaxel-albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of GP40071 Compared to NovoRapid® Penfill® in Type 1 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: GP40071|DRUG: NovoRapid® Penfill®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of the Femoral Nerve Block on Quadriceps Strength
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: DRUG: 48-hour ropivacaine infusions|DRUG: Single dose ropivacaine|DRUG: Patient controlled analgesics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Antihypertensive Intervention Management
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Hypertension|Vascular Diseases
Interventions: BEHAVIORAL: diet, reducing|BEHAVIORAL: diet, sodium-restricted|DRUG: chlorthalidone|DRUG: atenolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Pilot Investigation to Evaluate Effectiveness of Shockwave Therapy, Photobiomodulation and Physical Therapy in the Management of Non-insertional Achilles Tendinopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Achilles Tendinopathy
Interventions: DEVICE: Shockwave Therapy|DEVICE: Photobiomodulation Therapy|OTHER: Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human Antithrombin (rhAT) in Patients With Hereditary Antithrombin Deficiency Undergoing Surgery or Delivery
Status: COMPLETED
Conditions: Antithrombin III Deficiency
Interventions: BIOLOGICAL: Recombinant human antithrombin (rhAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pilot Phase II Study of Maintenance Cabozantinib Plus Pembrolizumab for Patients With Metastatic Squamous Non-Small Cell Lung Cancer (sqNSCLC)
Status: RECRUITING
Conditions: Metastatic Squamous Non-Small Cell Lung Carcinoma
Interventions: DRUG: Cabozantinib 40 MG|DRUG: Pembrolizumab 200mg|DRUG: Pembrolizumab 400mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omission of Axillary Surgery in Breast Cancer Patients
Status: RECRUITING
Conditions: Breast Cancer|Sentinel Lymph Node|Breast Neoplasms
Interventions: PROCEDURE: omission of SLNB in SentiOMIT or omission of ALND in SentiMACRO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tow Maxillary Hybrid Expanders Screw Supported Versus Lateral Angulated One; a Prospective Randomized Clinical Study
Status: UNKNOWN
Conditions: Cross Bite
Interventions: DEVICE: hybrid expanders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-64264681 in Healthy Male and Female Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-64264681|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Distribution of Secukinumab (AIN457) Into Dermal Interstitial Fluid After a Single Subcutaneous Administration of 300 mg
Status: COMPLETED
Conditions: Healthy|Psoriasis
Interventions: DRUG: secukinumab (AIN457)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Letrozole or Combined Metformin Clomiphene Citrate (CC) for Women With CC Resistant Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Letrozole tablets (Femara; Novartis Pharma, Switzerland)|DRUG: metformin HCl (Cidophage®; CID,Cairo, Egypt)|DRUG: CC (Clomid®; Global Napi Pharmaceuticals, Cairo, Egypt)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Presumptive Anthelminthic Treatment Delay the Progression of HIV in ART-naïve Patients in Rural Africa?
Status: TERMINATED
Conditions: HIV Infections|Helminthiasis
Interventions: DRUG: Praziquantel, Ivermectin, Albendazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening Wizard, Component 1 of iCHART (Integrated Care to Help At-Risk Teens)-Feasibility/Pilot Phase
Status: COMPLETED
Conditions: Depression|Suicidal Ideation
Interventions: BEHAVIORAL: Screening Wizard
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Oral Contraceptives, Insulin Resistance and Cardiovascular Risk Profile in Pre-Menopausal Women
Status: COMPLETED
Conditions: Insulin Sensitivity|Cardiovascular Risk|Perimenopausal Disorder
Interventions: DRUG: Ortho Cyclen®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Maximizing HPV Vaccination: Real-time Reminders, Guidance, and Recommendations - Part 4: Feasibility Trial
Status: NOT_YET_RECRUITING
Conditions: Human Papillomavirus (HPV) Vaccines
Interventions: BEHAVIORAL: Protect Me 4 Application + External Quality Improvement Support|BEHAVIORAL: Protect Me 4 Application Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase 1/2 Study to Evaluate the Efficacy and Safety of Inhaled IBIO123 in Participants With Mild to Moderate COVID-19 Illness
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: IBIO123|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Crossover Bioequivalence Study of Irbesartan 300 mg Tablets Under Fasted Conditions
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Irbesartan|DRUG: Avapro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Soy as an Innovative Dietary Component in Abdominal Obesity Management Amongst Peri- and Early Menopausal Women
Status: COMPLETED
Conditions: Central Obesity
Interventions: DIETARY_SUPPLEMENT: soy supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Insulin Glargine Against Insulin Aspart Infused Under the Skin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2|Delivery Systems
Interventions: DEVICE: pump|DRUG: insulin glargine|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of 1592U89 Plus 141W94 Plus DMP 266 in Patients With HIV Who Developed a Resistance to Protease Inhibitors
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Abacavir sulfate|DRUG: Amprenavir|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy Combined With Targeted Treatment in High-risk Retroperitoneal Sarcoma
Status: ENROLLING_BY_INVITATION
Conditions: Retroperitoneal Sarcoma
Interventions: DRUG: Doxorubicin+Ifosfamide+Anlotinib(AI+A)|PROCEDURE: Radical Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Local Treatment(Carrageenan Nasal Spray and PVP-I Mouthwash) in Reducing Viral Load in Patients With COVID-19
Status: COMPLETED
Conditions: Covid19|SARS-CoV 2 Infection
Interventions: DRUG: Carrageenan nasal spray and 1% PVP- mouthwash and gargle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab, Autologous Tumor/DC Vaccine, IL-2 and IFNα-2b in Metastatic Renal Cell Carcinoma (RCC) Patients
Status: TERMINATED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: BIOLOGICAL: DC vaccine|DRUG: Bevacizumab|BIOLOGICAL: IL-2|BIOLOGICAL: IFN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opiate Prescribing Guidelines Following Hip Arthroscopy
Status: COMPLETED
Conditions: Hip Injuries
Interventions: OTHER: Group 1 - Opiate Tablets post Hip Arthroscopy|OTHER: Group 2 - Opiate Tablets post Hip Arthroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Gum Arabic as Anti-oxidant, Anti-inflammatory and Fetal Hemoglobin Inducing Agent in Sickle Cell Anemia Patients
Status: UNKNOWN
Conditions: Sickle Cell Anemia in Children
Interventions: DIETARY_SUPPLEMENT: Acacia Senegal extract|DIETARY_SUPPLEMENT: Pectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Miglustat Therapy on Infantile Type of Sandhoff and Taysachs Diseases (EMTISTD)
Status: RECRUITING
Conditions: GM2 Gangliosidosis|Supportive Care
Interventions: DRUG: Miglustat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study To Compare The Amount Of Premarin Components That Is Absorbed Into The Blood Of Japanese Healthy Postmenopausal Women Following Oral Administration Of Two Different Tablets Of Premarin Under Fast and Fed Conditions.
Status: COMPLETED
Conditions: Primary Ovarian Insufficiency|Vaginitis|Metrorrhagia|Menopause
Interventions: DRUG: Premarin reference tablet (fasted)|DRUG: Premarin new tablet (fasted)|DRUG: Premarin reference tablet (fed)|DRUG: Premarin new tablet (fed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase II Study of Belatacept (BMS-224818) With a Steroid-free Regimen in Subjects Undergoing Kidney Transplantation
Status: COMPLETED
Conditions: Disorder Related to Renal Transplantation
Interventions: DRUG: Thymoglobulin|DRUG: Belatacept|DRUG: Sirolimus|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil (MMF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diffusion Weighted Magnetic Resonance Imaging and the Optic Nerve Neuropathy.
Status: UNKNOWN
Conditions: Ischemic Optic Neuropathy|Optic Neuritis|Compressive Optic Neuropathy|Traumatic Optic Neuropathy|Toxic Optic Neuropathy|Hereditary Optic Neuropathies
Interventions: DEVICE: Neuroimaging|DIAGNOSTIC_TEST: VEP - visual evoked potential|DIAGNOSTIC_TEST: Ophthalmology examination.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Procedural Sequences in Same-day Painless Bidirectional Endoscopy With Colonoscopic Water Exchange Method
Status: COMPLETED
Conditions: Colon Disease|Bidirectional Endoscopy
Interventions: BEHAVIORAL: colonoscopy first|BEHAVIORAL: EGD first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Long Term Follow up Study of Patients Who Have Complete Clearance of Their Actinic Keratosis (AK) Lesions at the Day 57 Visit in the PEP005-028 Study
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Lesion count
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Digital vs Analog Impression in Cases of All-on-4 - Prosthesis
Status: COMPLETED
Conditions: Edentulous Mouth
Interventions: OTHER: DIG Axial|OTHER: DIG Tilted|OTHER: CIG Axial|OTHER: CIG Tilted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effects of Oral NMRA-335140 Versus Placebo in Participants With Major Depressive Disorder
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: NMRA-335140|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autoflor -Lyophilized Capsulated Autological FMT to Restore Gut Microbiome After Treatment With Antibiotics
Status: NOT_YET_RECRUITING
Conditions: Microbial Colonization|Antibiotic Side Effect
Interventions: OTHER: FMT|OTHER: Placebo|DRUG: Amox Clav
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Kinesiotaping the Hand in Cerebral Palsy
Status: COMPLETED
Conditions: Spasticity
Interventions: DEVICE: Kinesiotape plus thenar pressure (PPTG)|DEVICE: Taping Group (TG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Patient Positioning and Use of Belly Board on Small Bowel and Urinary Bladder Volume Irradiated in Patients Receiving Radiotherapy for Rectal Cancer: A Prospective Phase II Study
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: RADIATION: Patient Position During Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BIOAVAILABILITY OF Glimepiride/Extended Release Metformin (GLI/METXR): High Fat Diet Study
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Glimepiride/ Extended release Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Omega-3 PUFA Supplementation in NAFLD Patients
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: Omega-3 fatty acid diet supplementation|DIETARY_SUPPLEMENT: safflower oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Efficacy of CC-5013 (Revlimid or Lenalidomide) in Patients With Primary Systemic Amyloidosis
Status: COMPLETED
Conditions: Amyloidosis
Interventions: DRUG: CC-5013
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Trial of MSC2490484A, an Inhibitor of a DNA-dependent Protein Kinase, in Combination With Radiotherapy
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: MSC2490484A (M3814)|RADIATION: Fractionated RT|DRUG: Cisplatin|DRUG: MSC2490484A (M3814)|DRUG: MSC2490484A (M3814)|RADIATION: Fractionated RT|RADIATION: Fractionated RT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Lidocaine Vaginal Gel for Recurrent Dysmenorrhea (Painful Periods)
Status: COMPLETED
Conditions: Dysmenorrhea
Interventions: DRUG: Lidocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Erlotinib and Surgery in Treating Patients With Head and Neck Cancer That Can Be Removed by Surgery
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: erlotinib hydrochloride|GENETIC: protein analysis|GENETIC: western blotting|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: liquid chromatography|OTHER: mass spectrometry|PROCEDURE: neoadjuvant therapy|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expanded Access Program Using Uromune for Patients With Recurrent Urinary Tract Infections (rUTI)
Status: NO_LONGER_AVAILABLE
Conditions: Urinary Tract Infections|Chronic Urinary Tract Infection|Recurrent Urinary Tract Infection|Urinary Tract Infection Bacterial|Bladder Infection
Interventions: BIOLOGICAL: Uromune
Study Type: EXPANDED_ACCESS
Clinical trial: Thyroid Treatment Trial
Status: COMPLETED
Conditions: Graves Ophthalmopathy
Interventions: DRUG: Intravenous Methylprednisolone + Oral Methotrexate vs Intravenous Methylprednisolone + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effects of Oxytocin on Attentional Bias and Startle in PTSD
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: Oxytocin|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Exploring the Effects of an Intravaginal Lactic Acid Gel on the Vaginal Microbiome
Status: RECRUITING
Conditions: Bacterial Vaginosis|Vulvovaginal Candidiasis
Interventions: DRUG: Phexxi
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of a 12-Week Regimen of Telaprevir, Pegylated Interferon, and Ribavirin in Treatment-Naive and Prior Relapser Subjects With Interleukin28B (IL28B) CC Genotype
Status: TERMINATED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Telaprevir|DRUG: Pegylated Interferon Alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Xyrem® (Sodium Oxybate) to Treat Fibromyalgia.
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: placebo|DRUG: Xyrem®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Radiolabeled rhAnnexin V-128 in Infective Endocarditis
Status: TERMINATED
Conditions: Endocarditis|Thrombosis
Interventions: DRUG: 99mTc-Annexin V-128 SPECT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Cardioviva™ Probiotic Supplement Capsule Formulation
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Cardioviva™ supplement capsule|DIETARY_SUPPLEMENT: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-Lymphatic STI-3031 Using the Sofusa DoseConnect Device for Treatment of In-Transit Melanoma, The Sofusa-2 Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Clinical Stage III Cutaneous Melanoma AJCC v8|Melanoma|Metastatic Melanoma|Recurrent Metastatic Melanoma
Interventions: BIOLOGICAL: Anti-PD-L1 Monoclonal Antibody IMC-001|PROCEDURE: Punch Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Cognitive Source of Visual Working Memory Impairment in Schizophrenia
Status: UNKNOWN
Conditions: Memory Deficits Schizophrenia Neurostimulator; Complications
Interventions: DEVICE: STARSTIM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Music Therapy in Patients Undergoing Pancreatic Surgery (MUSIC PUPS)
Status: RECRUITING
Conditions: Whipple Procedure|Distal Pancreatectomy|Acute Pain
Interventions: BEHAVIORAL: Music Assisted Relation Intervention (MARI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: 20-valent Pneumococcal Conjugate Vaccine Safety Study in Healthy Infants
Status: COMPLETED
Conditions: Pneumococcal Disease
Interventions: BIOLOGICAL: 20-valent pneumococcal conjugate vaccine|BIOLOGICAL: 13-valent pneumococcal conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Difference in Pain Perception by Patients With Prostate Biopsy Using Instillagel Compared With Guided Ultrasound Gel
Status: WITHDRAWN
Conditions: Prostate Biopsy
Interventions: OTHER: ultrasound gel|OTHER: Instillagel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE