pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Long-Term Safety of Ospemifene 60 mg Oral Daily Dose for the Treatment of Vulvar and Vaginal Atrophy (VVA) in Postmenopausal Women Without a Uterus
Status: COMPLETED
Conditions: Atrophy|Vaginal Diseases
Interventions: DRUG: Ospemifene 60Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Bladder Pressure Versus Regional Intestinal Tissue Oxygenation in Infants
Status: RECRUITING
Conditions: Intraabdominal Hypertension|Abdominal Compartment Syndrome
Interventions: DIAGNOSTIC_TEST: Near infrared-spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety And Tolerability Study Of BID Titration Scheme With PF-05089771
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-05089771|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Telerehabilitation With Aims to Improve Lower Extremity Recovery Post-Stroke
Status: COMPLETED
Conditions: Stroke|Stroke, Ischemic|Stroke Hemorrhagic|Cerebral Infarction|Brain Diseases|Central Nervous System Diseases|Cerebral Vascular Disorder|Brain Ischemia|Brain Infarction|Cardiovascular Diseases|Infarction
Interventions: BEHAVIORAL: Telerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Capecitabine in Elderly Cancer Patient (≥ 75 Years)
Status: COMPLETED
Conditions: Breast Cancer|Colorectal Cancer
Interventions: DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Umbilical Cord Tissue-derived Mesenchymal Stem Cells for Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Umbilical cord mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b Trial to Evaluate the Safety of MB310 in Patients With Active, Mild-to-Moderate Ulcerative Colitis
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis
Interventions: BIOLOGICAL: MB310|OTHER: Placebo|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Human Mesenchymal Stem Cells for Treatment of Liver Failure
Status: UNKNOWN
Conditions: Liver Failure|Mesenchymal Stem Cells
Interventions: DRUG: Conventional plus MSC treatment|DRUG: Conventional plus pacebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Different Modalities of Management of Odontogenic Keratocysts
Status: RECRUITING
Conditions: Odontogenic Cysts
Interventions: PROCEDURE: Enucleation+ Peripheral Ostectomy+Carnoy's solution chemical cauterization (E+CS + PO)|PROCEDURE: Decompression/ marsupialization (D/M)|PROCEDURE: Enucleation (E)|PROCEDURE: Enucleation+Carnoy's solution (E+CS)|PROCEDURE: Enucleation+ Peripheral Ostectomy (E+ PO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Two-Week Brain Stimulation for Teenagers With ADHD
Status: RECRUITING
Conditions: ADHD
Interventions: DEVICE: Intermittent Theta Burst Stimulation to the Left Dorsolateral Prefrontal Cortex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Travoprost Ophthalmic Solution, 0.004% Compared to Timolol (0.5% or 0.25%) in Pediatric Glaucoma Patients
Status: COMPLETED
Conditions: Pediatric Glaucoma|Elevated IOP in Pediatric Patients|Ocular Hypertension in Pediatric Patients
Interventions: DRUG: Travoprost 0.004% PQ ophthalmic solution|DRUG: Timolol, 0.5% or 0.25% ophthalmic solution|DRUG: Travoprost Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular Degeneration
Status: RECRUITING
Conditions: Dry Age-Related Macular Degeneration|Geographic Atrophy
Interventions: DRUG: iPSC-derived RPE/PLGA transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systemic Thrombolysis Versus Catheter Directed Management for Acute Intermediate-high Pulmonary Embolism
Status: NOT_YET_RECRUITING
Conditions: Acute Pulmonary Embolism
Interventions: DRUG: Streptokinase Injection|DEVICE: Penumbra System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of BL-B16D1 in Patients With Unresectable Locally Advanced or Metastatic Breast Cancer and Other Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Solid Tumor
Interventions: DRUG: BL-B16D1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Methadone Maintenance Versus Methadone Detox in Jail
Status: UNKNOWN
Conditions: Opioid-Related Disorders
Interventions: BEHAVIORAL: Methadone Maintenance|BEHAVIORAL: Linkage to methadone maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Skin and Serum Carotenoids in Preterm Infants Fed on a Formula Supplemented With Carotenoids
Status: COMPLETED
Conditions: Retinopathy of Prematurity
Interventions: DIETARY_SUPPLEMENT: carotenoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Aromatherapy Applied After Cesarean Section on Pain Intensity and Comfort Level
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: OTHER: Ylang Ylang oil with inhalation|OTHER: Lavender oil with inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Arthroscopic Versus Open Stabilization for Traumatic Shoulder Instability
Status: COMPLETED
Conditions: Joint Instability|Shoulder Dislocation
Interventions: PROCEDURE: Open stabilization|PROCEDURE: Arthroscopic stabilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rivaroxaban and Vitamin K Antagonists for the Anticoagulation for the Implantation of Vena Cava Filters
Status: RECRUITING
Conditions: Venous Thromboembolism
Interventions: DRUG: Rivaroxaban|DRUG: Warfarin|DRUG: Nadroparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy Group for Older Adults Delivered by Telethealth
Status: TERMINATED
Conditions: Major Depressive Disorder|Generalized Anxiety Disorder|Social Anxiety Disorder|Panic Disorder
Interventions: BEHAVIORAL: Group Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Chemoradiotherapy and Thymosin α1 in Unresectable or Recurrent Thymic Epithelial Tumor
Status: UNKNOWN
Conditions: Thymoma and Thymic Carcinoma
Interventions: DRUG: Thymosin a1|RADIATION: hypofractionated radiotherapy|DRUG: concurrent chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Continuous Furosemide Effect on Cardiac Surgery Patients With Kidney Dysfunction
Status: COMPLETED
Conditions: Chronic Kidney Disease|Cardiac Disease
Interventions: DRUG: Furosemide in 0.9 % NaCl 100 Mg/100 mL (1 mg/mL)|DRUG: NaCl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: LDE225 in Patients With Advanced or Metastatic Hepatocellular Carcinoma and Child-Pugh A/B7 Cirrhosis
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Cirrhosis
Interventions: DRUG: LDE225
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation of Visual Attention Following mTBI
Status: UNKNOWN
Conditions: Traumatic Brain Injury
Interventions: OTHER: Visual Attention Program (UCR Games)|OTHER: Speech Pathologist-Directed Therapy|OTHER: General Cognitive Rehabilitation Games (Lumosity)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Thoracoabdominal Aortic Stent System for Endovascular Treatment of Thoracoabdominal Aortic Dissecting Aneurysm.
Status: RECRUITING
Conditions: Thoracoabdominal; Aortic, Aneurysm, Dissecting
Interventions: DEVICE: Thoracoabdominal aortic stent system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of PK Similarity of FYB206 in Comparison With Keytruda in Resected Stage II or III Melanoma Patients
Status: RECRUITING
Conditions: Melanoma, Stage II|Melanoma Stage III
Interventions: BIOLOGICAL: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Dehydropeiandrosterone and Growth Hormone in Women With Expected Poor Ovarian Response Undergoing ICSI
Status: UNKNOWN
Conditions: Subfertility
Interventions: DRUG: DHEA|DRUG: Growth hormone|DRUG: Placebo 1|DRUG: Placebo 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Analysis of Suction Drainage in Cementless Hip Replacement
Status: COMPLETED
Conditions: Arthropathy of Hip
Interventions: PROCEDURE: suction drainage|PROCEDURE: no suction drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Excision and Intralesional Steroid Injection for Prevention of Post Caesarean Keloid Recurrence
Status: COMPLETED
Conditions: Keloid
Interventions: DRUG: Dexamethasone|OTHER: surgical excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Crenolanib in Recurrent/Refractory Glioblastoma With PDGFRA Gene Amplification
Status: COMPLETED
Conditions: Recurrent/Refractory Glioblastoma
Interventions: DRUG: crenolanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Osteopathic Manipulation in the the Management of Post-traumatic Migraine
Status: COMPLETED
Conditions: Migraine Disorders|Post-Traumatic Headache
Interventions: OTHER: Osteopathic Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study Evaluating Ixabepilone Plus Capecitabine or Docetaxel Plus Capecitabine in Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Neoplasms
Interventions: DRUG: Ixabepilone, 40 mg/m^2 + Capecitabine, 1000 mg/m^2|DRUG: Ixabepilone, 32 mg/m^2 + Capecitabine, 1000 mg/m^2|DRUG: Docetaxel, 75 mg/m^2 + Capecitabine, 1000 mg/m^2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Treatment for Nightmares in REM Sleep Behavior Disorder
Status: RECRUITING
Conditions: Nightmare|Nightmare Disorder With Associated Other Sleep Disorder|REM Sleep Behavior Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Nightmares
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of MRA for Polyarticular Juvenile Idiopathic Arthritis (pJIA)
Status: COMPLETED
Conditions: Systemic Juvenile Idiopathic Arthritis
Interventions: DRUG: MRA(Tocilizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Controlled Comparison of Pulsed Radiofrequency Vs Physical Therapy on Treating Chronic Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Percutaneous Pulsed Radiofrequency|PROCEDURE: Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing STR (Skeletal Targeted Radiotherapy) Plus Melphalan to Melphalan Alone, With Stem Cell Transplant in Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: STR(TM) (Skeletal Targeted Radiotherapy, Holmium-166-DOTMP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LUT014 for the Reduction of Dose-Limiting Acneiform Lesions Associated With EGFRI Treatment of mCRC
Status: RECRUITING
Conditions: EGFRI Induced Acneiform Lesions
Interventions: DRUG: LUT014 Gel (Dose 1)|DRUG: LUT014 Gel (Dose 2)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Infusion of Panobinostat (MTX110) Into the Fourth Ventricle in Children and Adults With Recurrent Medulloblastoma
Status: RECRUITING
Conditions: Medulloblastoma
Interventions: DRUG: Treatment with MTX110
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Awareness Based Stress Reduction Program Applied to Breast Cancer Patients Receiving Chemotherapy
Status: RECRUITING
Conditions: Breast Cancer Patients Receiving Chemotherapy
Interventions: OTHER: Mindfulness: Awareness-Based Stress Reduction Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TLR9 Agonist SD-101, Ibrutinib, and Radiation Therapy in Treating Patients With Relapsed or Refractory Grade 1-3A Follicular Lymphoma
Status: COMPLETED
Conditions: Grade 1 Follicular Lymphoma|Grade 2 Follicular Lymphoma|Grade 3a Follicular Lymphoma|Recurrent Follicular Lymphoma|Refractory Follicular Lymphoma|Mantle Cell Lymphoma|Marginal Zone Lymphoma
Interventions: DRUG: Ibrutinib|RADIATION: Radiation Therapy|DRUG: TLR9 Agonist SD-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep NMB in Ambulatory Gynecological Laparoscopy
Status: COMPLETED
Conditions: Muscle Relaxation
Interventions: DRUG: Rocuronium|DRUG: Rocuronium bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Telemedicine for Improving Outcome in Inner City Patient Population With Hypercapneic Respiratory Failure
Status: TERMINATED
Conditions: Hypercapnic Respiratory Failure|Chronic Obstructive Pulmonary Disease|Obesity Hypoventilation Syndrome|Sleep Disordered Breathing|Neuromuscular Diseases
Interventions: OTHER: Vivify|OTHER: EMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study To Assess GW677954 Used In Combination With Insulin In Subjects Who Have Type 2 Diabetes Mellitus
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus|Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin|DRUG: Oral GW677954 Capsules (15 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Acceptability of Using Low-Gain Hearing Aids for Bothersome Tinnitus
Status: COMPLETED
Conditions: Tinnitus|Hearing Aids|Normal Hearing
Interventions: DEVICE: Receiver in the canal (RIC) hearing aids
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Open-Label Study to Determine the Maximum Tolerated Oral Dose of the Kinase Inhibitor CEP-11981 in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: CEP-11981 (kinase inhibitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of AffronEye®/ Crocuvis+® on Dry Eye Syndrome
Status: NOT_YET_RECRUITING
Conditions: Dry Eye Syndrome
Interventions: DIETARY_SUPPLEMENT: Saffron extract (Crocus sativus)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of a Machine Learning-based Lower Limb Exercise Training System for Knee Pain
Status: UNKNOWN
Conditions: Pain
Interventions: DEVICE: Machine learning-based exercise training system|DEVICE: Video-based exercise training system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cosmetic Fat Transplantation Using Expanded ASC Enriched Fat Grafts
Status: COMPLETED
Conditions: Breast Hypoplasia and Facial Ageing
Interventions: BIOLOGICAL: ASC enriched lipofilling|BIOLOGICAL: Standard Lipofilling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Ischaemic Postconditioning in the Clinical Setting of NSTEACS and Urgent PCI
Status: COMPLETED
Conditions: Post Procedural Myocardial Infarction
Interventions: DEVICE: Remote Conditioning|DEVICE: Sham protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of IAP0971 in Combination With Bacillus Calmette Guerin in High Risk Non-muscular Invasive Bladder Cancer
Status: NOT_YET_RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: IAP0971|COMBINATION_PRODUCT: IAP0971＋BCG|COMBINATION_PRODUCT: IAP0971＋BCG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Mobile Heath Augmented Brief Suicide Prevention Intervention for People With SMI
Status: COMPLETED
Conditions: Schizophrenia|Bipolar Disorder|Suicide and Self-harm
Interventions: BEHAVIORAL: Safety and Recovery Therapy|BEHAVIORAL: Mobile Augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Microburst Vagus Nerve Stimulator (VNS) Therapy Feasibility Study
Status: COMPLETED
Conditions: Epilepsies, Partial|Epilepsy, Tonic-Clonic
Interventions: DEVICE: Microburst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tinzaparin on Inflammatory Biomarkers During the Acute Phase of Deep Vein Thrombosis
Status: RECRUITING
Conditions: Deep Vein Thrombosis|Inflammatory Response
Interventions: DRUG: Tinzaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Diagnostic and Disease Stage Biomarkers in AD
Status: RECRUITING
Conditions: Alzheimer Disease|Mild Cognitive Impairment|Neuro-Degenerative Diseases|Vascular Dementia|Dementia With Lewy Bodies|Healthy Controls
Interventions: OTHER: Long-term study|OTHER: Short-term study|OTHER: Cross-sectional study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mindfulness- Based Intervention for Fibromyalgia Patients
Status: COMPLETED
Conditions: Psychological
Interventions: OTHER: Mindfulness- Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of a Comprehensive Prevention Program to Reduce Lymphedema After Axillary Lymph Node Dissection in People with Breast Cancer
Status: RECRUITING
Conditions: Lymphedema|Lymphedema Arm|Lymphedema of Upper Arm|Breast Cancer|Breast Carcinoma|Female Breast Cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Influence of PBM on Anaerobic Capacity Under Normoxia and Hypoxia
Status: ACTIVE_NOT_RECRUITING
Conditions: Low Level Laser Therapy|Photobiomodulation|Performance|Sport
Interventions: DEVICE: Photobiomodulation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Role of Endoscopic Ultrasound in Evaluation of Patients With Indefinite Cause of Bile Duct Dilatation
Status: NOT_YET_RECRUITING
Conditions: Bile Duct Diseases
Interventions: DEVICE: Endoscopic ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A First-in-Man, Phase I Evaluation of A Single Cycle of Prohibitin Targeting Peptide 1 in Patients With Metastatic Prostate Cancer and Obesity
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Prohibitin-TP01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quintuple Method for Treatment of Multiple Refractory Colorectal Liver Metastases
Status: NOT_YET_RECRUITING
Conditions: For Patients With Colorectal Cancer Liver Metastases Who Were Not Able to Curative Surgical Resection.Focused on the Treatment Effect With the Quintuple Method
Interventions: DRUG: Oxaliplatin|DRUG: S1|DRUG: Cetuximab|DRUG: Metronidazole|DRUG: Vitamin A|DRUG: Folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Robotic-Assisted Gait Training in Patients With Stroke (EoRAGTiPwS)
Status: COMPLETED
Conditions: Stroke, Robotic Rehabilitation
Interventions: OTHER: Exoskeleton ExoAthlet group|OTHER: Lokomat Free-D group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Role of the Ketogenic Diet in Women With PCOS
Status: NOT_YET_RECRUITING
Conditions: Polycystic Ovary Syndrome
Interventions: BEHAVIORAL: ketogenic diet|COMBINATION_PRODUCT: caloric diet with Metformin|BEHAVIORAL: caloric diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does Autologous Conditioned Plasma Enhance Rotator Cuff Tendon Healing After Surgery?
Status: UNKNOWN
Conditions: Supraspinatus Tear
Interventions: OTHER: Autologous conditioned plasma (ACP)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Auto-titrating Oxygen in Chronic Respiratory Failure
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Idiopathic Pulmonary Fibrosis
Interventions: DEVICE: Auto-titrating oxygen system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of the Flow Diverter (Tonbridge) for Endovascular Treatment of Intracranial Aneurysms
Status: RECRUITING
Conditions: Intracranial Aneurysm
Interventions: DEVICE: Flow Diverter (Tonbridge)|DEVICE: Tubridge (MicroPort)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Repetitive Transcranial Magnetic Stimulation on Brain Activity in Healthy Human Volunteers
Status: COMPLETED
Conditions: Changes in EEG During and After Magnetic Stimulation
Interventions: DEVICE: true left high frequency|DEVICE: Passive sham left high frequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Liraglutide Therapy in Patients With IPAA
Status: TERMINATED
Conditions: Pouchitis|Irritable Pouch Syndrome
Interventions: DRUG: Liraglutide Pen Injector|DRUG: Placebo Pen Injector
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The CONFUCIUS Oral Protein Supplementation Trial
Status: UNKNOWN
Conditions: Intensive Care Unit Acquired Weakness|Critical Illness
Interventions: DIETARY_SUPPLEMENT: Porcine protein supplement|DIETARY_SUPPLEMENT: Control product maltodextrin supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Change in Reward System Activation and Gut Microbiota Following RYGB and Sleeve Gastrectomy for Weight Loss vs. Control-Heads Up Ancillary
Status: COMPLETED
Conditions: Bariatric Surgery Candidate
Interventions: PROCEDURE: Bariatric Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Natural History of Gene Expression in the Lung Cells of Non-Smokers, Smokers and Ex-Smokers in Health and Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)|Smoking|Smoking Cessation|Chronic Bronchitis|Emphysema
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Air as a Placebo: Increasing the Respiratory Performance of People With COPD Through Simple Expectations of Improvement
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Oxygen Therapy|OTHER: Compressed Medical Air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Impact of AI on Trainee ADR
Status: RECRUITING
Conditions: Adenoma|Adenoma Colon|Colorectal Cancer
Interventions: DIAGNOSTIC_TEST: AI use in Endoscopy Room|OTHER: Non-AI use Standard of Care endoscopy room
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Belantamab Mafodotin, Lenalidomide, and Daratumumab for the Treatment of Relapsed, Refractory, or Previously Untreated Multiple Myeloma
Status: COMPLETED
Conditions: Plasma Cell Myeloma|Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: BIOLOGICAL: Belantamab Mafodotin|BIOLOGICAL: Daratumumab|DRUG: Dexamethasone|DRUG: Lenalidomide|OTHER: Quality-of-Life Assessment|PROCEDURE: Biospecimen Collection|PROCEDURE: Skeletal Survey X-Ray|PROCEDURE: Low Dose Computed Tomography of the Whole Body|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INTERCEPT Blood System for RBCs Study in Regions at Potential Risk for Zika Virus Transfusion-Transmitted Infections
Status: RECRUITING
Conditions: Anemia
Interventions: DEVICE: INTERCEPT Blood System for Red Blood Cells|DEVICE: Conventional (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Food Effect Study of CT-L01 After Oral Administration in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CT-L01 12.5/1,000 mg|DRUG: CT-L01 12.5/1,000 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Ibuprofen Postoperative Analgesia After Abdominal Hysterectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Post Operative Analgesia
Interventions: DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chinese Spondyloarthritis Inception Cohort (CESPIC)
Status: NOT_YET_RECRUITING
Conditions: Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA)|Non-radiographic Axial Spondyloarthritis (Nr-axSpA)|Axial Psoriatic Arthritis (axPsA)|Acute Anterior Uveitis (AAU)|Crohn Disease (CD)|Ulcerative Colitis (UC)|Reactive Arthritis (ReA)
Interventions: DRUG: Celecoxib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Safety and Efficiency of Sildenafil in the Treatment of Severe Post-capillary Pulmonary Hypertension Caused by COPD
Status: UNKNOWN
Conditions: COPD|Pulmonary Hypertension
Interventions: DRUG: Sildenafil Citrate|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Learn if Odronextamab Combined With Chemotherapy is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Chemotherapy for Adult Participants With Follicular Lymphoma
Status: RECRUITING
Conditions: Follicular Lymphoma (FL)
Interventions: DRUG: Odronextamab|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone/Prenisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lapatinib, Cisplatin, Gemcitabine as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Urothelial Cancer
Status: COMPLETED
Conditions: Bladder Cancer|Transitional Cell Cancer of the Renal Pelvis and Ureter
Interventions: DRUG: cisplatin|DRUG: gemcitabine hydrochloride|DRUG: lapatinib ditosylate|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of GX15-070MS in Untreated CLL
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: GX15-070MS|DRUG: GX15-070MS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GW786034 In Subjects With Locally Recurrent Or Metastatic Clear Cell Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: GW786034|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-dose Vaginal Misoprostol Versus Vaginal Dinoprostone Insert for Induction of Labor
Status: COMPLETED
Conditions: Induced Labor|Cervical Ripening|Obstetric Labor|Pregnancy
Interventions: DRUG: Misoprostol 25 mcg|DRUG: Dinoprostone 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Therapy Versus Standard Therapy in Decompensated NASH Related Cirrhosis: A Randomized Controlled Trial.
Status: WITHDRAWN
Conditions: NASH Related Decompensated Cirrhosis
Interventions: DRUG: Fecal Microbiota Transplantation|DRUG: Standard Treatment|OTHER: Weight Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of the Dissociation Constant (Ka) of Plasma and Whole Blood in Septic Patients
Status: UNKNOWN
Conditions: Sepsis|Septic Shock|Critical Illness|Respiratory Acidosis|Respiratory Alkalosis|Acid-Base Imbalance
Interventions: DIAGNOSTIC_TEST: In vitro determination the dissociation constant (Ka) and total amount of non-volatile buffers (Atot) in isolated plasma.|DIAGNOSTIC_TEST: In vitro determination the dissociation constant (Ka) and total amount of non-volatile buffers (Atot) in whole blood|DIAGNOSTIC_TEST: Biomolecular analysis of plasma proteins.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Comparing Daratumumab, VELCADE (Bortezomib), Lenalidomide, and Dexamethasone (D-VRd) With VELCADE, Lenalidomide, and Dexamethasone (VRd) in Participants With Untreated Multiple Myeloma and for Whom Hematopoietic Stem Cell Transplant is Not Planned as Initial Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Bortezomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resistant Starch Prebiotic Effects in Chronic Kidney Disease
Status: RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: DIETARY_SUPPLEMENT: Resistant Potato Starch, Corn Starch|DIETARY_SUPPLEMENT: Corn Starch, Resistant Potato Starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Dulanermin in Combination With Rituximab in Subjects With Follicular and Other Low Grade, CD20+, Non-Hodgkin's Lymphomas
Status: TERMINATED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Dulanermin|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buparlisib (BKM120) In Patients With Recurrent/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Recurrent/Refractory Secondary Central Nervous System Lymphoma (SCNSL)
Status: COMPLETED
Conditions: Lymphoma|Primary Central Nervous System Lymphoma|Recurrent/Refractory Secondary Central Nervous System Lymphoma
Interventions: DRUG: Buparlisib (BKM120)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Portal Flu Vaccine Reminders (RCT 6)
Status: ACTIVE_NOT_RECRUITING
Conditions: Influenza|Respiratory Tract Infections
Interventions: BEHAVIORAL: Portal-based Video Message|BEHAVIORAL: Portal-based Infographic Message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of IMC-11F8 in Participants With Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: BIOLOGICAL: IMC-11F8|BIOLOGICAL: IMC-11F8|BIOLOGICAL: IMC-11F8
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DEnosumab for the Treatment of FIbrous Dysplasia/McCune-Albright Syndrome in Adults (DeFiD)
Status: RECRUITING
Conditions: Fibrous Dysplasia|McCune Albright Syndrome
Interventions: DRUG: Denosumab 120 Mg/1.7 Ml Inj|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fulvestrant or Tamoxifen in Treating Postmenopausal Women Who Are Undergoing Surgery for Ductal Carcinoma in Situ of the Breast
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: fulvestrant|DRUG: tamoxifen citrate|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of a MCYI as Adjunct to Psychiatric Treatment for Vietnam Veterans With PTSD - RCT
Status: UNKNOWN
Conditions: Posttraumatic Stress Disorder|Depression
Interventions: BEHAVIORAL: Multi-component Yoga Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: ECT
Clinical trial: Memory Priming in General Anesthesia
Status: COMPLETED
Conditions: Unconscious (Psychology)
Interventions: BEHAVIORAL: Abstract priming|BEHAVIORAL: Concrete priming|BEHAVIORAL: Controls|DRUG: Propofol|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact of Artichoke Leaf Extract on Blood Cholesterol: Primary Study
Status: WITHDRAWN
Conditions: Lipid Metabolism Disorders
Interventions: DIETARY_SUPPLEMENT: Artichoke Leaf Extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open, Multicenter Phase II Study to Evaluate the Safety and Efficacy of KL-A167 Injection in Relapsed or Refractory Classical Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Classical Hodgkin Lymphoma
Interventions: DRUG: KL-A167
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effects of Different Soft Tissue Mobilizations on Delayed Onset Muscle Soreness
Status: COMPLETED
Conditions: Muscle Soreness
Interventions: OTHER: Foam roller application|OTHER: Massage application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GRASSP: Gralise® for Spine Surgery Pain
Status: COMPLETED
Conditions: Post-laminectomy Pain Syndrome
Interventions: DRUG: Gralise®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Treatment With Intercalated Radiotherapy in EGFR-mutant IIIA/IIIB NSCLC
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer|Epidermal Growth Factor Receptor
Interventions: DRUG: Erlotinib Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1 Antibody Combined With Modified FLOT Regimen in the Treatment of Unresectable Locally Advanced or Limited Metastatic Gastric Cancer
Status: UNKNOWN
Conditions: Metastatic Gastric Cancer|Locally Advanced Gastric Adenocarcinoma
Interventions: DRUG: Camrelizumab plus mFLOT regimen|PROCEDURE: R0 surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vagal Nerve Stimulation as an Alternative Therapy for Premature Ventricular Contractions
Status: NOT_YET_RECRUITING
Conditions: Premature Ventricular Contraction
Interventions: DEVICE: Low-Level Tragus Stimulation|BEHAVIORAL: Heart Rate Variability- Biofeedback|OTHER: Conventional Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Extension Study Of Tofacitinib In Psoriatic Arthritis
Status: COMPLETED
Conditions: Arthritis, Psoriatic
Interventions: DRUG: Tofacitinib|DRUG: Tofacitinib|DRUG: Methotrexate|DRUG: Placebo Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lapatinib With Trastuzumab in Treating Patients With HER2-Negative/HER2 Mutant Metastatic Breast Cancer
Status: WITHDRAWN
Conditions: Breast Neoplasms
Interventions: DRUG: lapatinib ditosylate|BIOLOGICAL: trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Effect of a Synbiotic on Body Fat Mass
Status: COMPLETED
Conditions: Type 2 Diabetes|Metabolic Syndrome|Obesity, Abdominal|Obesity, Visceral
Interventions: DIETARY_SUPPLEMENT: synbiotic|DIETARY_SUPPLEMENT: microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Steps for Disinfection of Teeth With Primary Endodontic Infections
Status: COMPLETED
Conditions: Periapical Periodontitis|Bacterial Infections
Interventions: PROCEDURE: Root canal preparation|PROCEDURE: Intracanal medication
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome of Treatment With Secukinumab in the Treatment of Moderate to Severe Plaque Psoriasis at Tertiary Care Hospital.
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Secukinumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Industry-independent Visits to Primary Care Physicians on Medication Prescribing for Pain Relief in Chronic Joint Pain.
Status: COMPLETED
Conditions: Study Focus: Prescribing of Drugs
Interventions: BEHAVIORAL: academic detailing intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Persistent Epithelial Ovarian Cancer, Fallopian Tube, or Primary Peritoneal Cancer
Status: UNKNOWN
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: etoposide phosphate|DRUG: paclitaxel|DRUG: thiotepa|DRUG: topotecan hydrochloride|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Pioglitazone Incretin Study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combined Triple Procedure in Retinal Vein Occlusion (RVO)
Status: COMPLETED
Conditions: Retinal Vein Occlusion
Interventions: DRUG: triamcinolone and bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Effectiveness of TLD Radiofrequency Ablation in the Treatment of COPD
Status: RECRUITING
Conditions: COPD
Interventions: DEVICE: TLD|OTHER: Sham TLD procedure|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Therapy Versus Standard Therapy in NASH Related Cirrhosis.
Status: UNKNOWN
Conditions: Non Alcoholic Steatohepatitis
Interventions: BIOLOGICAL: Fecal Microbiota Transplant|OTHER: Standard Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Cervical Cerclage in Twin Pregnancies With Non-shortened Cervix
Status: RECRUITING
Conditions: Preterm Birth|Twin Pregnancy, Antepartum Condition or Complication|Cervical Cerclage
Interventions: PROCEDURE: Cervical cerclage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial to Treat Patients With ITP Who Do Not Achieve a Durable Response to Rituxan Alone
Status: WITHDRAWN
Conditions: Idiopathic Thrombocytopenic Purpura (ITP)
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tablet-based Cognitive Training
Status: RECRUITING
Conditions: Alzheimer Disease|Dementia|Mild Cognitive Impairment
Interventions: DEVICE: Computerized Cognitive Training|DEVICE: Documentaries with delayed Computerized Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of a Hydration Protocol "at Thirst" on Natremia of the Ultra Trail du Mont-Blanc, 2015 Runners
Status: COMPLETED
Conditions: Athletes|Healthy
Interventions: OTHER: Hydration when thirsty.|OTHER: Not hydration when thirsty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Meta-analysis of the Prognostic Value of Lymphocyte to Monocyte Ratio (LMR) in Non-metastatic Renal Cell Carcinoma.
Status: UNKNOWN
Conditions: Renal Cell Carcinoma|Progression|Lymphocyte Disorder|Monocytosis|Local Disease
Interventions: OTHER: prognosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p