pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Phase 1 Study of Tegoprazan on Healthy Male Volunteers
Status: UNKNOWN
Conditions: Pharmacodynamics|Pharmacokinetics|Healthy Male Volunteers
Interventions: DRUG: Tegoprazan (C1)|DRUG: Tegoprazan (C1)|DRUG: Treatment C: Tegoprazan (C1)|DRUG: Tegoprazan (C2)|DRUG: Tegoprazan (C2)|DRUG: Esomeprazole (C2)|DRUG: Tegoprazan (C3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Personalized Health Education Against the Health Damage of Novel Coronavirus (COVID-19) Outbreak in Hungary
Status: TERMINATED
Conditions: SARS-CoV-2|Coronavirus|COVID-19|2019-nCoV|2019nCoV
Interventions: BEHAVIORAL: Personalized health education|BEHAVIORAL: General health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Photodynamic Therapy With HPPH in Treating Patients With Squamous Cell Carcinoma of the Oral Cavity
Status: WITHDRAWN
Conditions: Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Verrucous Carcinoma of the Oral Cavity|Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage I Squamous Cell Carcinoma of the Oropharynx|Stage I Verrucous Carcinoma of the Oral Cavity|Stage II Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage II Squamous Cell Carcinoma of the Oropharynx|Stage II Verrucous Carcinoma of the Oral Cavity|Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage III Squamous Cell Carcinoma of the Oropharynx|Stage III Verrucous Carcinoma of the Oral Cavity|Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVA Squamous Cell Carcinoma of the Oropharynx|Stage IVA Verrucous Carcinoma of the Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Oropharynx|Stage IVB Verrucous Carcinoma of the Oral Cavity|Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVC Squamous Cell Carcinoma of the Oropharynx|Stage IVC Verrucous Carcinoma of the Oral Cavity
Interventions: DRUG: HPPH|DEVICE: Light Infusion Therapy™|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bedside Ultrasound Assessment of Gastric Content and Volume
Status: COMPLETED
Conditions: Gastroscopy
Interventions: OTHER: Ultrasound examination followed by ingestion of Apple Juice prior to a second ultrasound procedure, followed by gastroscopic suctioning of stomach content.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effects of Progressive Resistance Training Compared With Aerobic Training in Patients With Hemophilia
Status: COMPLETED
Conditions: Quality of Life|Muscle Weakness
Interventions: OTHER: Progressive resistance training|OTHER: Aerobic training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Long-term Prucalopride Treatment With Chronic Constipation in Subjects Aged ≥ 18 Years
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: placebo|DRUG: prucalopride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NY-ESO-1 Protein With Montanide and CpG 7909 as Cancer Vaccine in Several Tumors
Status: COMPLETED
Conditions: Tumors
Interventions: BIOLOGICAL: NY-ESO-1 Protein Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Assess the Effects in the Body of a Single Dose of Trientine Dihydrochloride in Wilson's Disease Patients
Status: COMPLETED
Conditions: Wilson's Disease
Interventions: DRUG: trientine dihydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Computerized Cognitive Training on Mood and Thinking Style Amongst Patients in Inpatient Settings
Status: COMPLETED
Conditions: Depression|Anxiety|Anhedonia
Interventions: BEHAVIORAL: Positive Mental Imagery Training (PMIT)|BEHAVIORAL: Cognitive Control Training (CCT)|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cochlear-Vestibular Ganglion (CVG) in Newly Diagnosed Type 2 Diabetes Patients
Status: WITHDRAWN
Conditions: Diabetes Mellitus Type 2 in Obese
Interventions: BEHAVIORAL: Social Cognitive Theory Tailored Behavioral Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Food Effect on Pharmacokinetics and Safety of DHP107 (Liporaxel®) FEEL Study
Status: COMPLETED
Conditions: Advanced Solid Tumor
Interventions: DRUG: DHP107(Oral paclitaxel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity & Safety of GSK's Influenza Vaccine 1557484A Given to Adults Aged ≥18 Years
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza A (H5N1) Virus Monovalent Vaccine, Adjuvanted|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating the Efficacy of a Reduced Dose Atazanavir in HIV-1-infected Patients
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Atazanavir 200 mg/r
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultra Protective Ventilation During Venoarterial Extracorporeal Membrane Oxygenation (UPV-ECMO)
Status: COMPLETED
Conditions: Cardiogenic Pulmonary Edema|Ventilator-Induced Lung Injury|Extracorporeal Circulation; Complications
Interventions: DEVICE: Ultraprotective ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety and Efficacy of WS016 in Patients With Hyperkalemia.
Status: RECRUITING
Conditions: Hyperkalemia
Interventions: DRUG: WS016 3g|DRUG: WS016 6g|DRUG: WS016 12g|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Artificial Intelligence to Predict Surgical Outcomes and Assess Pain Neuromodulation in Trigeminal Neuralgia Subjects
Status: RECRUITING
Conditions: Trigeminal Neuralgia|Trigeminal Nerve Diseases|Virtual Reality|Artificial Intelligence|Radiosurgery|Magnetic Resonance Imaging
Interventions: PROCEDURE: GKRS-VR training|PROCEDURE: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Treatment of Hypovitaminosis D Increase Calcium Absorption?
Status: COMPLETED
Conditions: Osteoporosis|Osteopenia|Vitamin D Deficiency|Hypoparathyroidism|Hypercalciuria|Hypercalcemia
Interventions: DRUG: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Stem Cells for Skin Grafts in Donor Site Wounds
Status: RECRUITING
Conditions: Skin Wound|Scar, Hypertrophic
Interventions: PROCEDURE: human umbilical cord mesenchymal stem cells|PROCEDURE: blank solvent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Pilot Testing of the Students With Autism Accessing General Education (SAAGE) Model
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Students with Autism Accessing General Education|OTHER: Enhanced Services As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phantom Motor Execution Via MPR, VR/AR, and SG, as a Treatment of PLP
Status: COMPLETED
Conditions: Phantom Limb Pain
Interventions: DEVICE: Phantom Motor Execution|DEVICE: Phantom Motor Imagery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ESWT as a Treatment for Chronic NHO in TBI Patients
Status: COMPLETED
Conditions: TBI Traumatic Brain Injury
Interventions: DEVICE: ESWT - Extracorporeal Shockwave Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of MEDI-507 in With Steroid-Resistant Acute Graft-Versus-Host Disease
Status: COMPLETED
Conditions: Cancer|Graft-Versus-Host Disease
Interventions: DRUG: MEDI-507|DRUG: MEDI-507
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Augmentation of Exposure Therapy for High Levels of Social Anxiety Using Post-exposure Naps
Status: COMPLETED
Conditions: Social Anxiety Disorder|Sleep Laboratory
Interventions: BEHAVIORAL: Sleep-enhancement of extinction memory
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Optimal Delay Time to Initiate Anticoagulation After Ischemic Stroke in Atrial Fibrillation
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke
Interventions: OTHER: Time-To-Treatment Randomization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clevidipine in the Treatment of Patients With Acute Hypertension and Intracerebral Hemorrhage (ACCELERATE)
Status: COMPLETED
Conditions: Hypertension|Hemorrhage
Interventions: DRUG: clevidipine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy of Prolonged-Release Melatonin Versus Placebo in Diabetic Patients Suffering From Insomnia
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Insomnia
Interventions: DRUG: Circadin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of SCTA01 Against COVID-19 in Patients Admitted to High Dependence or Intensive Care
Status: UNKNOWN
Conditions: Covid19
Interventions: BIOLOGICAL: SCTA01|BIOLOGICAL: SCTA01 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Pilot Study of Mixed Chimerism to Treat Inherited Metabolic Disorders
Status: TERMINATED
Conditions: Hurler Syndrome (MPS I)|Hurler-Scheie Syndrome|Hunter Syndrome (MPS II)|Sanfilippo Syndrome (MPS III)|Krabbe Disease (Globoid Leukodystrophy)|Metachromatic Leukodystrophy (MLD)|Adrenoleukodystrophy (ALD and AMN)|Sandhoff Disease|Tay Sachs Disease|Pelizaeus Merzbacher (PMD)|Niemann-Pick Disease|Alpha-mannosidosis
Interventions: BIOLOGICAL: hematopoietic stem cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Types of Artificial Tears
Status: UNKNOWN
Conditions: Dry Eye Disease
Interventions: DRUG: Thealoz Duo (combination of trehalose and hyaluronate) eye drop and Hyabak (hyaluronate) eye drop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Automated Insulin Delivery (AID) for Basal Insulin Titration in Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DEVICE: Control-IQ use in Type 2 Diabetes under basal insulin injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Saving Lives at Birth in Uganda: Building and Sustaining Capacity of Frontline Health Workers - A Program Evaluation
Status: COMPLETED
Conditions: Postpartum Hemorrhage|Neonatal Asphyxia
Interventions: OTHER: Helping Mothers Survive - Bleeding After Birth training|OTHER: Helping Babies Breathe|BEHAVIORAL: Mentor|BEHAVIORAL: Phone|DRUG: oxytocin and misoprostol|DEVICE: Newborn bag and mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Improving the Outcomes of Peritoneal Dialysis (PD) Catheter Insertion
Status: UNKNOWN
Conditions: Peritoneal Dialysis Access Failure|Peritoneal Dialysis Complication
Interventions: DEVICE: Peritoneal Catheter Insertion - Laparoscopic|DEVICE: Peritoneal Catheter Insertion - Percutaneous
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Protocol for Radiofrequency Ablation of Pulmonary Neoplasms
Status: TERMINATED
Conditions: Pulmonary Neoplasms
Interventions: PROCEDURE: Radiofrequency Ablation of pulmonary neoplasms
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensity-modulated Radiotherapy (IMRT) With Simultaneous Integrated Boost (SIB) for Inoperable Non-small-cell Lung Cancer
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer
Interventions: RADIATION: IMRT + SIB + Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: E-Cigarette Inner City RCT
Status: UNKNOWN
Conditions: Tobacco Dependence|COPD Asthma|Mental Illness|Substance Use
Interventions: DEVICE: Improved Quality of Life of low-income Canadians that smoke tobacco and other substances
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Auditory Stimulation Effects on Sleep and Memory in Patients With Epilepsy
Status: RECRUITING
Conditions: Epilepsy
Interventions: OTHER: Baseline|OTHER: Motor procedural memory task|OTHER: Motor procedural memory task plus auditory stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Umbilical Cord Mesenchymal Stem Cells Infusion for Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis|Mesenchymal Stem Cells|Umbilical Cord
Interventions: BIOLOGICAL: Umbilical Cord Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate a Single Intranasal Dose of STI-2099 (COVI-DROPS™) in Outpatient Adults With COVID-19 (UK)
Status: TERMINATED
Conditions: Covid19
Interventions: BIOLOGICAL: COVI-DROPS|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of the Efficacy of Palivizumab Administration in Children Born at 29-32 Weeks of Gestation
Status: COMPLETED
Conditions: Bronchial Hyperreactivity|Infant, Premature
Interventions: OTHER: Methacholine Challenge Test (MCT)|OTHER: Monthly telephone contact|OTHER: Visits to the study site|OTHER: Blood Test|OTHER: Fractional exhaled nitric oxide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of Google Translate to Enhance Patient Pain and Nausea Assessment and Satisfaction After General Anesthesia
Status: COMPLETED
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Medical Device Usage and Evaluation|OTHER: Survey Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Study of a Sensory Feedback Knee Orthosis in Patients Suffering From Unoperated Severe Knee Sprain
Status: TERMINATED
Conditions: Sprain
Interventions: DEVICE: ORTHOSENS orthosis|DEVICE: ORTHOSENS orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Therapy With Oxaliplatin/Docetaxel/Capecitabine and Radiation in Resectable Esophagus Cancer
Status: COMPLETED
Conditions: Esophagus Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Docetaxel|DRUG: Capecitabine|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Exposure Physical Therapy (PEPT) Versus CBO in Patients With Complex Regional Pain Syndrome Type I (CRPS-1)
Status: COMPLETED
Conditions: Complex Regional Pain Syndrome, Type I
Interventions: PROCEDURE: PEPT|PROCEDURE: CBO standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Obeticholic Acid（OCA） Combination With Ursodeoxycholic Acid (UDCA) in Patients With Primay Biliary Cirrhosis (PBC)
Status: UNKNOWN
Conditions: Primary Biliary Cirrhosis
Interventions: DRUG: Obeticholic Acid Tablets|DRUG: UDCA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Vulnerability Factors in Alcohol-dependence
Status: TERMINATED
Conditions: Alcoholism
Interventions: BEHAVIORAL: Diagnostic Interview for Genetic Studies|BEHAVIORAL: Family Informant Schedule and Criteria|BEHAVIORAL: Temperament and Character Inventory|BEHAVIORAL: Barratt Impulsiveness Scale|BEHAVIORAL: Wisconsin Card Sorting Test|GENETIC: blood sample withdrawn
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Safety Study of Allogeneic Mesenchymal Precursor Cells (MPCs) in Subjects With Recent Acute Myocardial Infarction
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: GENETIC: Allogeneic Mesenchymal Precursor Cells (MPCs)|PROCEDURE: Standard-of-care treatment with NOGA® mapping and staged injections.|GENETIC: Allogeneic Mesenchymal Precursor Cells (MPCs)|PROCEDURE: Standard-of-care treatment with NOGA® mapping and staged injections.|GENETIC: Allogeneic Mesenchymal Precursor Cells (MPCs)|PROCEDURE: Standard-of-care treatment with NOGA® mapping and staged injections.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Safety and Efficacy of Elagolix in Subjects With Moderate to Severe Endometriosis-Associated Pain
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: elagolix|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Multiple Doses of Natalizumab (BG00002) Administered Subcutaneously to Japanese Participants With Relapsing-Remitting Multiple Sclerosis
Status: TERMINATED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Natalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sub-Tenon's Injection of Triamcinolone and Ciprofloxacin in a Controlled-Release System for Cataract Surgery
Status: TERMINATED
Conditions: Inflammation|Bacterial Infections
Interventions: DEVICE: slow delivery ciprofloxacin + triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Adverse Events and Change in Disease Activity in Adult Participants With B-Cell Malignancies Receiving Oral ABBV-525 Tablets
Status: RECRUITING
Conditions: Diffuse Large B-Cell Lymphoma|Chronic Lymphocytic Leukemia|B Cell Malignancies|Non-Hodgkin's Lymphoma
Interventions: DRUG: ABBV-525
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin B12 and Dextrose for Median Nerve Hydrodissection
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Ultrasound-guided nerve hydrodissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Guided Internet-based Interventions in Primary Care Effectiveness-implementation Randomized Controlled Trial
Status: RECRUITING
Conditions: Anxiety|Mild to Moderate Depression
Interventions: BEHAVIORAL: Guided internet-based cognitive behavioural therapy|BEHAVIORAL: Treatment as usual in Prompt Mental Health Care (TAU-PMHC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of 177Lu-PSMA617 Theranostic Versus Cabazitaxel in Progressive Metastatic Castration Resistant Prostate Cancer
Status: COMPLETED
Conditions: Cancer of the Prostate|Metastatic Cancer
Interventions: OTHER: 177Lu-PSMA617|DRUG: Cabazitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Cryptosporidiosis in AIDS Patients
Status: TERMINATED
Conditions: Cryptosporidiosis|HIV Infections
Interventions: DRUG: Interleukin-12|DRUG: Paromomycin sulfate|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Investigation of PSMA PET/CT as an Imaging Biomarker in Solid Tumors
Status: RECRUITING
Conditions: Prostate-specific Membrane Antigen|mCRPC or Advanced/Metastatic Solid Tumors
Interventions: DRUG: 68Ga-PSMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Methimazole in Graves' Disease - Comparing the Computer-aided Treatment DigiThy Versus Usual Care
Status: NOT_YET_RECRUITING
Conditions: Graves Disease
Interventions: DEVICE: Semi-automated computer-aided treatment (Digital Thyroid, DigiThy)|PROCEDURE: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: m-Rehab OSA : Impact of a Telerehabilitation Program Associated With CPAP on Severity Markers of Obstructive Sleep Apnea Syndrome
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: OTHER: Telerehabilitation solution (m-Rehab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a Life Stories Methodologies in Long-Term Care Centres
Status: ACTIVE_NOT_RECRUITING
Conditions: Long-term Care Centres for Old Adults Users|Relatives of Long-term Care Centres for Old Adults Users|Long-term Care Centres for Old Adults Professionals
Interventions: COMBINATION_PRODUCT: Envita Stories Methodology in Long-term care Centres for old adults|BEHAVIORAL: Contact Methodology in Long-term Care Centres for old adults
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immediate Effects of TECAR Therapy on the Quadriceps Muscle Performance in Athlete: A Randomized Crossover Trial
Status: UNKNOWN
Conditions: TECAR Therapy|Muscle Performance|Athletes
Interventions: DEVICE: Active Tecar|DEVICE: Placebo Tecar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Professional Continuous Glucose Monitoring as an Adjuvant Educational Tool for Improving Glycemic Control in Patients With Type 2 Diabetes.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: Professional continuous glucose monitoring (CGM) sensor (iPro™2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Physical Activity Intervention to Reduce Functional Health Disparities Among Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Cancer|Physical Activity
Interventions: BEHAVIORAL: Aerobic Training - Fixed Schedule|BEHAVIORAL: Resistance Training - Fixed Schedule|BEHAVIORAL: Walking program|BEHAVIORAL: Aerobic Training - Flexible Schedule|BEHAVIORAL: Resistance Training - Flexible Schedule|BEHAVIORAL: Successful Survivorship Health Education and Support Group|BEHAVIORAL: Flexible support groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Test the Effects and Safety of Riliprubart in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) for Which the Usual Treatments do Not Work
Status: RECRUITING
Conditions: Chronic Inflammatory Demyelinating Polyradiculoneuropathy|Polyneuropathy, Inflammatory Demyelinating, Chronic
Interventions: DRUG: Riliprubart|DRUG: Placebo|DRUG: Riliprubart|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phenol With Fluoroscopy Guided Radiofrequency Ablation of T2-T3in Palmar Hyperhidrosis.
Status: UNKNOWN
Conditions: Excessive Sweating of the Hands
Interventions: PROCEDURE: Surgical sympathectomy|PROCEDURE: Radiofrequency ablation with phenol injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Magnesium Sulphate Infusion on Lung Mechanics and Oxygenation in COPD Patients Undergoing Total Laryngeal
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Diseases
Interventions: DRUG: Magnesium Sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Versus Late Intermaxillary Elastics in Patients With Class II Malocclusion
Status: COMPLETED
Conditions: Class II Malocclusion Division 1
Interventions: DEVICE: Early Class II elastics|DEVICE: Conventional Class II elastics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health Beneficial Effects of Krill Oil and Lean and Fatty Fish
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Krill oil|OTHER: Lean and fatty fish|DIETARY_SUPPLEMENT: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: First-line Treatment of Ewing Tumours With Primary Extrapulmonary Dissemination in Patients From 2 to 50 Years
Status: COMPLETED
Conditions: Ewing Sarcoma Family of Tumors
Interventions: DRUG: VDC-IE x2|DRUG: VDC-IE|DRUG: TEMIRI|DRUG: Consolidation BuMel|DRUG: Maintenance|PROCEDURE: Local treatment by surgery|RADIATION: Local treatment by radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Blueberry Supplementation on Alzheimer's Biomarkers
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Alzheimer Disease
Interventions: DIETARY_SUPPLEMENT: lyophilized blueberry supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Direct Oral Anticoagulants (Rivaroxaban and Apixaban) in Patients With Liver Cirrhosis
Status: UNKNOWN
Conditions: Liver Cirrhosis
Interventions: DRUG: Rivaroxaban 10 mg Oral Tablet|DRUG: Apixaban 2.5 mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Trial of CK0801 (a New Drug) In Patients With Treatment-Resistant Guillain-Barré Syndrome (GBS)
Status: WITHDRAWN
Conditions: Guillain-Barré Syndrome
Interventions: BIOLOGICAL: CK0801
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Outcomes After Radial Head Fractures Treated Non-operatively
Status: COMPLETED
Conditions: Radial Head Fracture
Interventions: PROCEDURE: Outpatient physical therapy in addition to standard follow-up visits|BEHAVIORAL: Home exercises in addition to standard follow-up visits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining Bluetooth Haptic Device Use for Pain and Anxiety Reduction in Vascular Access Procedures
Status: NOT_YET_RECRUITING
Conditions: Pain|Anxiety
Interventions: BEHAVIORAL: Bluetooth Haptic Device (BHD)|BEHAVIORAL: BHD synced with mobile game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reducing Urethral Pain During Urodynamic Test - Comparison Between Lidocaine Gel and Paraffin Oil
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: Lidocaine Gel|DRUG: Paraffin Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Low-salt Bread in Heart Failure, Pilot Study
Status: COMPLETED
Conditions: Heart Failure, Systolic|Sodium Imbalance|Food Selection
Interventions: DIETARY_SUPPLEMENT: Low sodium bread|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Addition of Tobramycin Inhalation in the Treatment of Ventilator Associated Pneumonia
Status: COMPLETED
Conditions: Ventilator Associated Pneumonia (VAP)
Interventions: DRUG: tobramycin inhalation|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fludeoxyglucose F 18 PET Imaging in Determining Protein and Gene Expression Signatures in Patients With Premalignant Polyps or Colon Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Neoplasm of Uncertain Malignant Potential
Interventions: GENETIC: DNA methylation analysis|GENETIC: fluorescence in situ hybridization|GENETIC: gene expression analysis|GENETIC: polymerase chain reaction|GENETIC: protein expression analysis|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: diagnostic laboratory biomarker analysis|OTHER: immunoenzyme technique|OTHER: immunohistochemistry staining method|PROCEDURE: biopsy|PROCEDURE: therapeutic conventional surgery|RADIATION: fludeoxyglucose F 18
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of NNC-0156-0000-0009 During Surgical Procedures in Subjects With Haemophilia B
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia B
Interventions: DRUG: nonacog beta pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety, Tolerability, Pharmacokinetics and Immunogenicity of MEDI7352 in Healthy Volunteers
Status: COMPLETED
Conditions: Painful Osteoarthritis of the Knee
Interventions: DRUG: MEDI7352|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Study of XMT-1536 in Cancers Likely to Express NaPi2b
Status: ACTIVE_NOT_RECRUITING
Conditions: Platinum Resistant Ovarian Cancer|Non Small Cell Lung Cancer Metastatic
Interventions: DRUG: upifitamab rilsodotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Effect of Different Doses of Avenciguat (BI 685509) on Kidney Function in People With Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Avenciguat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial
Status: RECRUITING
Conditions: Recurrent Endometrial Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration and Biopsy|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|PROCEDURE: Multigated Acquisition Scan|DRUG: Olaparib|DRUG: Selumetinib Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Q-value Changes and Progression of Pediatric Keratoconus.
Status: COMPLETED
Conditions: Keratoconus|Collagen Diseases|Corneal Disease
Interventions: PROCEDURE: Transepithelial Corneal Collagen Cross-linking|DIAGNOSTIC_TEST: Scheimpflug camera
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adrenaline Reduces Ecchymoses and Hematomas and Improves Quality of Life After Classic Saphenous Vein Stripping
Status: COMPLETED
Conditions: Venous Insufficiency (Chronic)(Peripheral)|Venous Reflux|Venous Insufficiency of Leg|Venous Stasis|Venous Disease|Subcutaneous Haematoma|Ecchymosis|Bruising
Interventions: PROCEDURE: Great saphenous vein stripping and varicectomies|DRUG: Epinephrine Topical|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Trial of Pulsatile vs Non Pulsatile Perfusion on Short Term Changes in Kidney Function Using an Intra-Aortic Ballooon Pump During Cardioplegic Arrest in Patients Undergoing Myocardial Reperfusion
Status: COMPLETED
Conditions: Aortocoronary Bypass
Interventions: PROCEDURE: pulsatile intra-aortic balloon pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Automated Administration of Intravenous Compared With Inhalatory Anesthesia on the Occurrence of Postoperative Delirium
Status: UNKNOWN
Conditions: Postoperative Delirium|Elderly Patient|General Anesthetic Drug Adverse Reaction
Interventions: DRUG: Propofol|DRUG: Sevoflurane|DRUG: Remifentanil automatic|DRUG: Remifentanil manual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Leucine or Protein Supplementation and Resistance Training
Status: COMPLETED
Conditions: Skeletal Muscle
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: L-leucine + maltodextrin|DIETARY_SUPPLEMENT: Whey protein concentrate|DIETARY_SUPPLEMENT: Hydrolyzed whey protein concentrate|DIETARY_SUPPLEMENT: Soy protein concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of NH001 in Vegetative State & Minimally Conscious State Following a Traumatic Brain Injury
Status: SUSPENDED
Conditions: Brain Injury
Interventions: DRUG: Apomorphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Ultrasound-guided Scalp Block for Supratentorial Craniotomy
Status: RECRUITING
Conditions: Pain, Postoperative|Anesthesia
Interventions: PROCEDURE: Ultrasound-guided scalp block with ropivacaine 0.375%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of the Fixed Dose Combination of BI 1744 CL Plus BI 54903 XX Via Respimat® B Versus the Mono Products of BI 1744 CL Via Respimat® A and BI 54903 XX Via Respimat® B in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1744 CL/BI 54903 XX FDC|DRUG: BI 54903 XX|DRUG: BI 1744 CL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2a Study to Evaluate IcBD-01 Enema in Active Ulcerative Colitis Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: CBD, synthetic form|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Atherogenic Effects of Uric Acid-modified in Endothelial Dysfunction and the the Preventional Mechanism by Anthocyanidines
Status: UNKNOWN
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Anthocyanidins capsule|DIETARY_SUPPLEMENT: Placebo capsule|DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of MEDI9929 After Single Administration in Healthy Male Japanese Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: MEDI9929|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Investigational Scan (7 Tesla MRI) in Diagnosing Cognitive Impairment in Patients With Non-Metastatic Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Metastatic Prostate Carcinoma|Stage I Prostate Cancer AJCC v8|Stage II Prostate Cancer AJCC v8|Stage IIA Prostate Cancer AJCC v8|Stage IIB Prostate Cancer AJCC v8|Stage IIC Prostate Cancer AJCC v8|Stage III Prostate Cancer AJCC v8|Stage IIIA Prostate Cancer AJCC v8|Stage IIIB Prostate Cancer AJCC v8|Stage IIIC Prostate Cancer AJCC v8
Interventions: PROCEDURE: 7 Tesla Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Implantable Cardiac Monitor to Detect Atrial Fibrillation in Patients With MINOCA
Status: RECRUITING
Conditions: MINOCA|Atrial Fibrillation
Interventions: DEVICE: CONFIRM Rx implantable cardiac rhythm monitor (Abbott)|DIAGNOSTIC_TEST: Systematic etiologic work-up for underlying causes of MINOCA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Endoscopic Ultrasound - Based Sphincterotomy or Conservative Treatment in Severe Biliary Pancreatitis
Status: TERMINATED
Conditions: Pancreatitis Acute Biliary
Interventions: PROCEDURE: ultrasonography with or not sphincterotomy|PROCEDURE: Usual procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Vascular Injury in Diabetes Through Eye and Nailfold Data (DIVIDEND) - A Pilot Study
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: PROCEDURE: Video Nailfold Capillaroscopy|DEVICE: Ambulatory 24 hr Blood Pressure Monitoring|PROCEDURE: Fundoscopy of eyes|PROCEDURE: Laser Doppler Flowmetry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Statin Therapy In Patients With Vasospastic Angina
Status: WITHDRAWN
Conditions: Angina Pectoris, Variant|Statins, HMG-CoA
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short Term Closed-loop Glucose Control in Adults With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: FlorenceD or similar closed loop glucose control system|DEVICE: CSII with real-time CGM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and Bryostatin 1 in Treating Patients With Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: bryostatin 1|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Nitroglycerin for Retained Placenta Extraction: a Multicenter Study
Status: COMPLETED
Conditions: Retained Placenta
Interventions: DRUG: nitroglycerine|OTHER: NSS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Benefits From Bimodal Fittings With Cochlear Implant and Hearing Aid vs Bilateral Hearing Aids
Status: RECRUITING
Conditions: Hearing Loss, Cochlear
Interventions: DEVICE: Cochlear Implant and Hearing aid in bimodal solution|DEVICE: Bilateral hearing aids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ALXN1210 in Complement Inhibitor Treatment-Naïve Adult and Adolescent Participants With Atypical Hemolytic Uremic Syndrome (aHUS)
Status: COMPLETED
Conditions: Atypical Hemolytic Uremic Syndrome (aHUS)
Interventions: BIOLOGICAL: Ravulizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: -02341066 and PF-00299804 for Advanced Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-Small Cell Lung|Adenocarcinoma|Carcinoma, Squamous Cell|Carcinoma, Large Cell
Interventions: DRUG: PF-02341066/PF-00299804|DRUG: PF-02341066/PF-00299804
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Nilotinib (AMN107) Compared With Current Treatment Options in Patients With GIST Who Have Failed Both Imatinib and Sunitinib
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Nilotinib|OTHER: Best Supportive Care (BSC) +/- imatinib or sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Versus Lidocaine in Attenuating Airway Reflexes During Recovery of Thyroidectomy Patients
Status: RECRUITING
Conditions: Anesthesia|Airway Complication of Anesthesia
Interventions: DRUG: Dexmedetomidine|DRUG: Lidocaine IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Diclofenac Suppository to Control Pain During Flexible Cystoscopy
Status: COMPLETED
Conditions: Pain|Hematuria|Lower Urinary Tract Symptoms
Interventions: DRUG: Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Biofeedback Therapy Efficiency in Masticatory Muscles Pain Management
Status: NOT_YET_RECRUITING
Conditions: Muscle Pain|Feedback, Psychological|Craniomandibular Disorders|Temporomandibular Disorder|Sleep
Interventions: DEVICE: Electromyography Biofeedback|OTHER: Classic treatment for myogenous TMD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow Aspirate Concentrate Versus Triamcinolone Injection For Hip Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Hip Osteoarthritis
Interventions: COMBINATION_PRODUCT: Aspire Needle + Emcyte PureBMC|DRUG: Triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Velcade-based Regimen With Autologous Stem Cell Transplantation in Newly-diagnosed Myeloma Patients
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: velcade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study to Evaluate the Effect of Concomitant Renal Denervation and Cardiac Ablation on AF Recurrence
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation|Paroxysmal Atrial Fibrillation|Hypertension
Interventions: DEVICE: Renal Artery Ablation|DEVICE: Cardiac Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of N-Acetylcysteine in Improving/Normalizing ALT & AST in Patients of NAFLD
Status: NOT_YET_RECRUITING
Conditions: NAFLD
Interventions: BEHAVIORAL: Diet and exercise|DRUG: NAC with diet and exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT