pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Gaining Optimism After Weight Loss Surgery (GOALS) II
Status: RECRUITING
Conditions: Bariatric Surgery
Interventions: BEHAVIORAL: Positive Psychology-Motivational Interviewing|BEHAVIORAL: Physical Activity Education Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Right Ventricular Pacing in Pulmonary Arterial Hypertension
Status: UNKNOWN
Conditions: Pulmonary Artery Hypertension|Right Ventricular Dysfunction
Interventions: PROCEDURE: Temporary right ventricular pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acrylate Intraocular Lenses in Cataract Surgery of Uveitis Patients
Status: COMPLETED
Conditions: Uveitis|Cataract
Interventions: DEVICE: intraocular lenses: Two foldable, acrylic, sharp edged IOLs: AcrySof™ (AcrySof SA60AT, Alcon), and Akreos adapt™ (Bausch & Lomb)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: iPSC-based Drug Repurposing for ALS Medicine (iDReAM) Study
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Bosutinib (Phase 1 part)|DRUG: Bosutinib (Phase 2 part)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fosaprepitant for the Prevention of Nausea and Emesis During Concurrent Chemoradiotherapy for Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: fosaprepitant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the PICO 14 Negative Pressure Wound Therapy System in the Management of Acute and Chronic Wounds
Status: TERMINATED
Conditions: Surgical Incision|Ulcer Foot|Ulcer Venous|Ulcer, Leg|Pressure Ulcer|Wound Dehiscence
Interventions: DEVICE: PICO 14 single-use Negative Pressure Wound Therapy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATG Could Improve the Outcome Of Hematopoietic Stem Cell Transplant in Patients With Highly Aggressive T Cell Tumors
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia|Lymphoblastic Lymphoma
Interventions: DRUG: Rabbit Anti-human Thymocyte Globulin (ATG)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HepaSphere/Quadrasphere Microspheres for Delivery of Doxorubicin for the Treatment of Hepatocellular Cancer
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: HepaSphere/QuadraSphere Microspheres|PROCEDURE: PVA, lipiodol, doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Simultaneous Improvement in Colon Cancer Screening Rates and Patient-Centered Care
Status: COMPLETED
Conditions: Colon Cancer
Interventions: BEHAVIORAL: Decision Aid for Colon Cancer Screening|BEHAVIORAL: Usual Care Outreach for Colon Cancer Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Effectiveness of Amantadine and Propranolol for Treating Cocaine Dependence - 2
Status: COMPLETED
Conditions: Cocaine-Related Disorders
Interventions: DRUG: Propranolol|DRUG: Amantadine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tundra Gifts: Harvesting Local And Regional Resources To Prevent Obesity Among Alaska Native Children In Remote, Underserved Communities
Status: UNKNOWN
Conditions: Childhood Obesity
Interventions: BEHAVIORAL: Tundra Gifts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Oral Pregabalin on Epidural-induced Shivering and Epidural Characteristics
Status: COMPLETED
Conditions: Epidural Anesthesia|Shivering
Interventions: DRUG: Pregabalin 150mg|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic vs Open Pancreatectomy for Body and Tail Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer|Surgery|Laparoscopy
Interventions: PROCEDURE: Laparoscopic distal pancreatectomy|PROCEDURE: Open distal pancreatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrical Impedance Myography: Natural History Studies inNeuromuscular Disorders and Healthy Volunteers
Status: RECRUITING
Conditions: Neuromuscular Disease|Motor Neuron Disease|Inherited Neuromuscular Conditions|Inherited Neuropathies
Interventions: DEVICE: EIM testing|DEVICE: Nerve &amp; muscle ultrasonography|DEVICE: Nerve conduction studies|DEVICE: Electromyography (EMG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: TumorGraft- Guided Therapy for Improved Outcomes in Head and Neck Squamous Cell Cancer- A Feasibility Study
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: OTHER: Drug testing on PDX per Investigator's choice (upto 4)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Retinal Vascularization by Laser Doppler Velocimetry Coupled With an Adaptive Optics Camera ( AO-LDV)
Status: UNKNOWN
Conditions: Glaucoma|Retinal Vein Occlusion
Interventions: PROCEDURE: Laser Doppler Velocimetry + Optic Adaptative Camera
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Intravenous Anakinra and Ruxolitinib During COVID-19 Inflammation
Status: TERMINATED
Conditions: Covid-19
Interventions: DRUG: Anakinra alone (stages 2b/3)|DRUG: Anakinra and Ruxolitinib (overcome stage 3)|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Fucicort® Lipid Cream Compared to Combination Treatment With Fucidin® Cream Followed by Betamethasone (Lianbang Beisong®) Cream and Fucicort® Lipid Cream Vehicle in Clinically Infected Atopic Dermatitis/Eczema
Status: TERMINATED
Conditions: Infected Atopic Dermatitis/Eczema
Interventions: DRUG: Fucicort® Lipid cream|DRUG: Fucidin® cream|DRUG: Fucicort® Lipid cream vehicle|DRUG: betamethasone (Lianbang Beisong®) cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COOL AMI EU Pilot Trial to Assess Cooling as an Adjunctive Therapy to Percutaneous Intervention in Patients With Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: Cooling + PCI|DEVICE: PCI only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Palbociclib Combined With Afatinib for Advanced Squamous Carcinoma of Esophagus or Gastroesophageal Junction
Status: RECRUITING
Conditions: Esophagus Squamous Cell Carcinoma
Interventions: DRUG: Palbociclib|DRUG: Afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Establishment of Ideal IV Sedative Regimen for Successful Fiberoptic Bronchoscopy in Assessing the Site, Severity of Sleep Apnea Syndrome
Status: COMPLETED
Conditions: Sleep Apnea Syndrome
Interventions: DRUG: dexmedetomidine infusion rate, 0.5 mcg/kg/hr|DRUG: dexmedetomidine infusion rate, 1.0 mcg/kg/hr
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Decitabine and Peripheral Stem Cell Transplantation in Treating Patients Who Have Relapsed Following Bone Marrow Transplantation for Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: Filgrastim|DRUG: Cyclosporine|DRUG: Decitabine|PROCEDURE: Allogeneic Bone Marrow Transplantation|PROCEDURE: Peripheral Blood Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Deferiprone in Patients With Pantothenate Kinase-associated Neurodegeneration (PKAN)
Status: COMPLETED
Conditions: Pantothenate Kinase-Associated Neurodegeneration
Interventions: DRUG: Deferiprone oral solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remote State Representation in Early Psychosis
Status: RECRUITING
Conditions: Psychosis|Schizophrenia|Schizo Affective Disorder|Schizoaffective Disorder|Schizophreniform Disorders|Psychotic Disorders|Psychotic Mood Disorders|Psychoses, Affective|Psychosis Nos/Other|Schizophrenia Spectrum and Other Psychotic Disorders
Interventions: DEVICE: BrainHQ Computerized Cognitive Training - Visual Perception Training Paradigm|DEVICE: BrainHQ Computerized Cognitive Training - Visual Cognitive Control Training Paradigm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Ultra-processed Foods in Modulating the Effect of Mediterranean Diet
Status: NOT_YET_RECRUITING
Conditions: Overweight
Interventions: OTHER: MD high in UPF|OTHER: MD low in UPF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Anastomotic Leakage and Value Of Indocyanine Green in Decreasing Leakage Rates
Status: UNKNOWN
Conditions: Colo-rectal Cancer|Crohn Disease|Resectable Colorectal Carcinoma
Interventions: DRUG: ICG-guided bowel perfusion assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety Study of Liver Regeneration Therapy Using Cultured Autologous BMSCs
Status: UNKNOWN
Conditions: Liver Regeneration
Interventions: PROCEDURE: Autologous BMSCs|DRUG: bone marrow-derived mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Danazol Treatment in Endometriosis Women Before IVF
Status: COMPLETED
Conditions: Endometriosis|Ovarian Cysts|Infertility
Interventions: DRUG: Danazol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Su Jok Therapy on Postoperative Pain, Anxiety and Patient Satisfaction in Patients With BPH
Status: NOT_YET_RECRUITING
Conditions: Transurethral Resection (TUR) Syndrome
Interventions: OTHER: Intervention Su Jok Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Epoetin Alfa in Advanced Non-Small Cell Lung Cancer (EPO-CAN-20)
Status: TERMINATED
Conditions: Non-Small-Cell Lung Carcinoma|Lung Cancer|Anemia
Interventions: DRUG: Epoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Intensive Stuttering Group Therapy for School-age Children and the Effect of Emotional Reactivity on Therapy Outcomes
Status: COMPLETED
Conditions: Stuttering, Childhood|Emotion, Expressed
Interventions: BEHAVIORAL: individualized desensitization exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Substudy 'B' of the Accuracy of Ingestible Event Marker (IEM) Detection by the Medical Information Device #1 (MIND1)
Status: COMPLETED
Conditions: Device Latency
Interventions: DEVICE: MIND1 System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Escalating Dose Study in Healthy Volunteers With SEN0014196
Status: COMPLETED
Conditions: Huntington's Disease
Interventions: DRUG: SEN0014196|DRUG: SEN0014196|DRUG: SEN0014196|DRUG: SEN0014196|DRUG: SEN0014196|DRUG: SEN0014196|DRUG: SEN0014196|DRUG: SEN0014196|DRUG: SEN0014196|DRUG: SEN0014196|DRUG: SEN0014196
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-Dose Study in Normal Volunteers to Assess the Safety, Tolerability and Pharmacokinetics of STX107
Status: COMPLETED
Conditions: Fragile X Syndrome
Interventions: DRUG: STX107
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modifying Dietary Behavior in Adolescents With Elevated Blood Pressure
Status: COMPLETED
Conditions: Hypertension|Pre-Hypertension
Interventions: BEHAVIORAL: DASH-4-Teens|OTHER: Routine Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EMD 1201081 in Combination With Cetuximab in Second-Line Cetuximab-Naïve Subjects With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck Cancer
Interventions: DRUG: Cetuximab|DRUG: EMD 1201081
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Celecoxib, Capecitabine, and Irinotecan in Treating Patients With Recurrent or Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: capecitabine|DRUG: celecoxib|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hand Hygiene Practices and Microbial Contamination on Feeding Tubes and Other Components of Feeding Systems
Status: COMPLETED
Conditions: Enteral Nutrition|Microbial Colonization|Adherence
Interventions: OTHER: Adherence to Hand Hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Argyle Safety Fistula Cannula With Anti-reflux Valve Clinical Study
Status: RECRUITING
Conditions: End Stage Renal Failure on Dialysis
Interventions: DEVICE: Argyle Safety Fistula Cannula with Anti-Reflux Valve
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efemoral Vascular Scaffold System (EVSS) for the Treatment of Patients With Symptomatic Peripheral Vascular Disease From Stenosis or Occlusion of the Femoropopliteal Artery
Status: RECRUITING
Conditions: Peripheral Arterial Disease|Vascular Diseases|Stenosis|Femoropopliteal Stenosis
Interventions: DEVICE: Efemoral Vascular Scaffold System (EVSS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Cosmetic Product Against Telogen Effluvium on Women
Status: COMPLETED
Conditions: Telogen Effluvium
Interventions: OTHER: RV3466F lotion|OTHER: Shampoo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Surfactant Administration During Spontaneous Breathing
Status: UNKNOWN
Conditions: Pneumothorax|Pulmonary Interstitial Emphysema|Bronchopulmonary Dysplasia
Interventions: PROCEDURE: Take care|PROCEDURE: InSurE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pancreatoduodenectomy With Mesopancreas Dissection.A Prospective Study Comparing Artery-first Approach Versus Standard Approach
Status: UNKNOWN
Conditions: Periampullary Carcinoma Resectable
Interventions: PROCEDURE: Artery-first Approach|PROCEDURE: Standard Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Immunogenicity of GSK Biologicals' 10Pn-PD-DiT 4-dose Presentation to the Licensed 1-dose Synflorix™ (10Pn-PD-DiT) Vaccine When Co-administered With DTPw-combination Vaccine in Healthy Infants
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Pneumococcal vaccine GSK1024850A (10Pn-PD-DiT) vaccine (4-dose presentation)|BIOLOGICAL: Pneumococcal vaccine GSK1024850A (10Pn-PD-DiT) vaccine (1-dose presentation)|BIOLOGICAL: DTPw-HBV/Hib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Cytokine Clearance Between SLED-f Using High Cut-off Dialyzer and High-flux Dialyzer in Septic AKI Patients
Status: COMPLETED
Conditions: Sepsis|Acute Kidney Injury
Interventions: PROCEDURE: SLED-f with HCO dialyzer|PROCEDURE: SLED-f with HF dialyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of a Novel Cognitive-Behavioral Treatment for Posttraumatic Stress and Substance Dependence
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Substance Dependence
Interventions: BEHAVIORAL: Treatment for Integrated Posttraumatic Stress and Substance Use (TIPSS)|BEHAVIORAL: Cognitive-Behavioral Therapy for Substance Dependence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Response Capsaicin Flare Study
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-04427429|OTHER: Capsaicin challenge|DRUG: Placebo|OTHER: Capsaicin challenge|OTHER: EMLA positive control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Prospective Multicenter Observational Study and Promotion of the Application of Focused Ultrasound in Allergic Rhinitis
Status: RECRUITING
Conditions: Allergic Rhinitis
Interventions: PROCEDURE: High-intensity focused ultrasound (HIFU)|DRUG: intranasal corticosteroids, oral antihistamines, oral leukotriene receptor antagonists, and intranasal antihistamines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxygen Therapy for the Treatment of Undifferentiated Headache in the Emergency Department
Status: COMPLETED
Conditions: Headache
Interventions: BIOLOGICAL: Medical Air|BIOLOGICAL: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Provide Continued Access to Study Drug to Children and Adolescents Who Have Completed Clinical Studies Involving Gilead HIV Treatments
Status: NOT_YET_RECRUITING
Conditions: HIV-1-infection
Interventions: DRUG: F/TAF (High Dose Tablet)|DRUG: F/TAF (Low Dose Tablet)|DRUG: F/TAF (Lowest Dose Tablet)|DRUG: F/TAF (High Dose TOS)|DRUG: F/TAF (Low Dose TOS)|DRUG: F/TAF (Lowest Dose TOS)|DRUG: E/C/F/TAF|DRUG: E/C/F/TAF (Low Dose)|DRUG: Cobicistat (High Dose)|DRUG: Cobicistat (Low Dose)|DRUG: Cobicistat (TOS)|DRUG: B/F/TAF (High Dose)|DRUG: B/F/TAF (Low Dose)|DRUG: B/F/TAF (High Dose TOS)|DRUG: B/F/TAF (Low Dose TOS)|DRUG: B/F/TAF (Lowest Dose TOS)|DRUG: 3rd ARV Agent|DRUG: Nucleos(t)ide reverse transcriptase inhibitors (NRTI)|DRUG: ATV|DRUG: DRV|DRUG: Lopinavir Boosted with ritonavir (LPV/r)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Different Methods of Intramuscular Injection
Status: COMPLETED
Conditions: Injection Fear|Injection Site Bruising|Pain, Acute|Satisfaction, Patient|Hematoma
Interventions: PROCEDURE: Helfer Skin Tap Technique|PROCEDURE: ShotBlocker Technique|PROCEDURE: Standard Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dundrum Forensic Redevelopment Evaluation Study: D-FOREST Study.
Status: RECRUITING
Conditions: Schizophrenia|Forensic Psychiatry|Outcome Measure|Violence|Personality Disorders|Recovery|Obesity|Type II Diabetes|Cardiovascular Diseases|Frailty|Psychosis|Treatment-resistant Schizophrenia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intra-articular Injection of Lidocaine in Inflammatory Arthritis
Status: UNKNOWN
Conditions: Inflammatory Arthritis
Interventions: DIAGNOSTIC_TEST: depomedrone 40mg/ml + 1% lidocaine|DIAGNOSTIC_TEST: depomedrone 40mg/ml+ 0.9% saline|OTHER: painDETECT questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Observational Study of Approaches to Lipid-Lowering Therapy in Russian Patients With Coronary Heart Disease <<Treat to Goal>> (Study P05464)
Status: COMPLETED
Conditions: Coronary Heart Disease|Hypercholesterolemia
Interventions: DRUG: Ezetimibe|DRUG: Statin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial to Evaluate the Pharmacokinetic and Pharmacodynamic Properties of BioChaperone® Insulin Lispro, Fiasp® and NovoRapid® Delivered by an Insulin Pump
Status: COMPLETED
Conditions: Type1 Diabetes Mellitus
Interventions: DRUG: BioChaperone® insulin lispro|DRUG: Fiasp®|DRUG: Novorapid®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Profile Comparison of Undiluted Intracameral Moxifloxacin vs. Levofloxacin in Cataract Surgery
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Moxifloxacin Ophthalmic Solution|DRUG: Levofloxacin Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Preconditioning for Renal Protection in TAVI
Status: COMPLETED
Conditions: Aortic Valve Stenosis|Renal Insufficiency|Contrast-induced Nephropathy
Interventions: PROCEDURE: Remote ischemic preconditioning|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Delayed 18F-FDG PET/CT in Improving Visualization of Brain Tumors in Patients With Glioblastoma
Status: WITHDRAWN
Conditions: Glioblastoma|Glioma
Interventions: PROCEDURE: Computed Tomography|RADIATION: Fludeoxyglucose F-18|PROCEDURE: Positron Emission Tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral TheraCLEC™ - Total in Cystic Fibrosis Subjects With Exocrine Pancreatic Insufficiency
Status: COMPLETED
Conditions: Cystic Fibrosis|Pancreatic Insufficiency
Interventions: DRUG: Liprotamase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Pharmacokinetics and Efficacy of KRN23 in Pediatric Chinese Patients With XLH
Status: COMPLETED
Conditions: X-linked Hypophosphatemia (XLH)
Interventions: DRUG: KRN23
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation in SCA3 Patients
Status: COMPLETED
Conditions: Spinocerebellar Ataxia Type 3
Interventions: DEVICE: Active repetitive transcranial magnetic stimulation|DEVICE: Sham repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Do Aromatase Inhibitors (AIs) Decrease Intestinal Calcium Absorption?
Status: COMPLETED
Conditions: Breast Cancer|Osteoporosis|Osteopenia|Fracture
Interventions: DRUG: Aromatase Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Idarubicin, Cytarabine, and Pravastatin Sodium in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Chronic Myelomonocytic Leukemia|de Novo Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable|Refractory Anemia With Excess Blasts|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: pravastatin sodium|DRUG: idarubicin|DRUG: cytarabine|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Administration of Clomiphene: Short and Long Term Metabolism in an Anti-Doping Setting
Status: COMPLETED
Conditions: Sports Drug Abuse|Abuse of Steroids or Hormones
Interventions: DRUG: Clomid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: DORAvirine Versus DOlutegravir Based Antiretroviral Regimens in Treatment-naïve People Living With HIV-1 Infection
Status: NOT_YET_RECRUITING
Conditions: HIV-1-infection
Interventions: DRUG: Doravirine + tenofovir DF + lamivudine|DRUG: Dolutegravir + tenofovir DF + lamivudine or emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Safinamide Mesilate as Add-on Therapy to Levodopa in Parkinson's Disease Participants With Motor Fluctuation in South Korea
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Safinamide Mesilate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Subclinical Atrial Fibrillation in High Risk Patients Using Implantable Loop Recorder
Status: COMPLETED
Conditions: Arterial Hypertension|Diabetes Mellitus
Interventions: OTHER: Conventional Holter monitoring|DEVICE: Implantable loop recorder
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Eculizumab Pharmacokinetics/Pharmacodynamics Study in Pediatric/Adolescent Paroxysmal Nocturnal Hemoglobinuria (PNH)
Status: COMPLETED
Conditions: Hemoglobinuria, Paroxysmal
Interventions: DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EPI-MINN: Targeting Cognition and Motivation
Status: RECRUITING
Conditions: Psychosis
Interventions: DEVICE: Cognitive and Social Cognitive Training|BEHAVIORAL: Personalized Real-Time Intervention for Motivational Enhancement (PRIME) App|OTHER: Early Psychosis Coordinated Specialty Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Placebo-controlled, Double-blind Study of KLH-2109 in Patients With Endometriosis (2)
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: KLH-2109|DRUG: KLH-2109|DRUG: KLH-2109|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Assessment of TCI633 Probiotics on Pain Relief and Functional Improvement in Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: TCI633|DRUG: Type 2 collagen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Amolimogene (ZYC101a) in Patients With High Grade Cervical Intraepithelial Lesions of the Uterine Cervix
Status: COMPLETED
Conditions: Uterine Cervical Dysplasia
Interventions: DRUG: Amolimogene|DRUG: Amolimogene|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Z-100 Plus Radiation Therapy to Treat Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DRUG: Z-100|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Denosumab on Normal BMD in Women Receiving Adjuvant Aromatase Inhibitors for Early Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Denosumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy and Radiation Therapy in Treating Young Patients With Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: cyclophosphamide|DRUG: dacarbazine|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: prednisone|DRUG: procarbazine hydrochloride|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effectiveness, Safety and Clinical Outcomes of Paritaprevir/Ombitasvir/r+Dasabuvir 8 Weeks
Status: COMPLETED
Conditions: Hepatitis C Infection
Interventions: DRUG: ombitasvir/paritaprevir/ritonavir 8 weeks|DRUG: dasabuvir 8 weeks
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gemcitabine and Celecoxib in Treating Patients With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Celecoxib|DRUG: Gemcitabine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Chlorambucil to Fludarabine in Patients With Advanced Waldenström Macroglobulinemia
Status: COMPLETED
Conditions: Waldenström Macroglobulinemia|Lymphoplasmacytic Lymphoma|Splenic Marginal Zone Lymphoma
Interventions: DRUG: Chlorambucil|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systemic Nalbuphine Versus Intravenous Regional Anesthesia
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Systemic nalbuphine|DRUG: Local nalbuphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CPASMA: Is There an Improvement in Asthma in Patients With Both Asthma and OSAS Treated With CPAP?
Status: UNKNOWN
Conditions: Asthma|Obstructive Sleep Apnea Syndrome
Interventions: DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Efficacy and Safety of Saxagliptin in Adult Patients With Type 2 Diabetes Inadequate Glycemic Control
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Saxagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: P3 Study in Acne Comparing Once Daily SB204 and Vehicle
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: SB204 4%|DRUG: Vehicle Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Hormone Replacement Therapy on Cardiovascular Risk and Body Composition Parameters
Status: UNKNOWN
Conditions: Menopause|Hormone Replacement Therapy
Interventions: DRUG: Oral hormone therapy (estradiol and micronized natural progesterone)|DRUG: Non-oral hormone therapy (estradiol and micronized natural progesterone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Androgen Deprivation Therapy and Apalutamide With or Without Radiation Therapy for the Treatment of Biochemically Recurrent Prostate Cancer, RESTART Study
Status: WITHDRAWN
Conditions: Biochemically Recurrent Prostate Carcinoma|Metastatic Prostate Carcinoma|Oligometastatic Prostate Carcinoma|Stage IV Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: DRUG: Apalutamide|DRUG: Degarelix|DRUG: Leuprolide Acetate|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Transporter Protein Inhibitor Probenecid In Patients With Epilepsy
Status: TERMINATED
Conditions: Epilepsy
Interventions: DRUG: phenytoin|DRUG: phenytoin and probenecid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Insulin Degludec/Liraglutide Combination (IDegLira) in Patients With Type 2 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: IDegLira|DRUG: Premixed insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Movement-oriented Dementia Care on ADL and QoL of Dementia Patients in Nursing Homes
Status: COMPLETED
Conditions: Dementia
Interventions: BEHAVIORAL: Movement-oriented Dementia Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Investigate the Effect of CYP3A Inhibition on the Pharmacokinetics of RG1662 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Patient Study
Interventions: DRUG: RG1662|DRUG: itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Indwelling Interscalene Nerve Catheters in Surgical Management of Idiopathic Adhesive Capsulitis
Status: UNKNOWN
Conditions: Frozen Shoulder
Interventions: PROCEDURE: Interscalene block with nerve catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Consumption of a Cheese Enriched With Probiotic Organisms in Improving Symptoms of Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DIETARY_SUPPLEMENT: Probiotic fresh cheese|DIETARY_SUPPLEMENT: Regular Cheese
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Determine the Effect of KP-001 on Metformin and Midazolam Pharmacokinetics and the Effect of Clarithromycin on KP-001 Pharmacokinetics in Healthy Adult Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Adults
Interventions: DRUG: KP-001|DRUG: Metformin|DRUG: Midazolam|DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Eplerenone in Reducing Recurrence of Atrial Fibrillation in Patients With Structural Heart Disease
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: Eplereone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Pristine Post-Market Study
Status: TERMINATED
Conditions: Kidney Failure, Chronic|Hemodialysis Complication|Hemodialysis Catheter Infection|Hemodialysis Access Failure|Central Venous Catheter Related Bloodstream Infection|End Stage Renal Disease
Interventions: DEVICE: Pristine™ Long-Term Hemodialysis Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Systemic Oxygen on Corneal Epithelial Wound Healing in Diabetic Patients Undergoing Pars Plana Vitrectomy
Status: COMPLETED
Conditions: Corneal Diseases
Interventions: DRUG: Dexamethasone 0.1%, Neomycin Sulfate and Polymyxin B Sulfate topical eye drops four times daily|DRUG: Homatropine 2% eye drops thrice daily|DRUG: Oxygen gas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Values to Enhance Inmates' Response to Substance Use and HIV Risk Feedback
Status: UNKNOWN
Conditions: Substance Use|HIV Risk Behavior
Interventions: BEHAVIORAL: Values Affirmation|BEHAVIORAL: Risk Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Superficial Cervical Plexus Block for IJCL Pain Management
Status: RECRUITING
Conditions: Superficial Cervical Plexus Block|Pain
Interventions: PROCEDURE: Superficial Cervical Plexus Block|PROCEDURE: Local Infiltrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Research Study To Evaluate If Frovatriptan Is Safe And Effective In Preventing Migraine Headache After Fasting
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Frovatriptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pasireotide to Reduce Clinically Relevant Digestive Leakage After Complete Cytoreductive Surgery (CRS) Plus Hyperthermic Intra-Peritoneal Chemotherapy (HIPEC) for Peritoneal Carcinomatosis
Status: TERMINATED
Conditions: Peritoneal Carcinomatosis
Interventions: DRUG: Pasireotide 0.9 MG/ML|OTHER: Saline water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of PAC-1 and Entrectinib for Patients With Metastatic Uveal Melanoma
Status: TERMINATED
Conditions: Uveal Melanoma
Interventions: DRUG: PAC-1|DRUG: Entrectinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incidence of Brachial Plexus Injury After Rotator Cuff Repair With Continuous Interscalene Block
Status: WITHDRAWN
Conditions: Brachial Plexus Injury
Interventions: PROCEDURE: Continuous interscalene block|PROCEDURE: PCA morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Guideline-directed Management and Therapy (GDMT) for the Prevention of Postpartum Cardiac Dysfunction in Preeclamptic African American Women
Status: RECRUITING
Conditions: Preeclampsia Postpartum
Interventions: DEVICE: Remote Patient Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Salutogenic Frailty Prevention Program for Women Aged 55 Years and Over
Status: UNKNOWN
Conditions: Frailty|Frailty Syndrome|Salutogenesis|Sense of Coherence
Interventions: BEHAVIORAL: Salutogenic Frailty Prevention Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Bioavailability of Vitamin D Photoisomers From UVB-exposed Button Mushrooms
Status: NOT_YET_RECRUITING
Conditions: Dietary Exposure|Safety Issues
Interventions: DIETARY_SUPPLEMENT: UVB-exposed button mushrooms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myorelaxant Effect of Bee Venom(BV) Topical Skin Application in Patients With RDC/TMD Ia and Ib
Status: COMPLETED
Conditions: Other Disorders of Muscle in Diseases Classified Elsewhere
Interventions: DIETARY_SUPPLEMENT: Bee Venom Ointment|OTHER: Vaseline Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long Term, Extension Study of the Safety and Efficacy of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type
Status: RECRUITING
Conditions: Agitation in Patients With Dementia of the Alzheimer's Type
Interventions: DRUG: AVP-786
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cytoreductive Surgery and HIPEC in First or Secondary Platinum-resistant Recurrent Ovarian Epithelial Cancer
Status: UNKNOWN
Conditions: Ovarian Epithelial Cancer
Interventions: PROCEDURE: Cytoreductive surgery combined with HIPEC|DRUG: Chemotherapy and bevacizumab (CT-BEV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate CD8 PET Imaging as a Marker of Immune Response to Stereotactic Body Radiation Therapy (ELIXR)
Status: RECRUITING
Conditions: Metastatic Malignant Solid Neoplasm|Lymphoma
Interventions: PROCEDURE: Positron Emission Tomography|RADIATION: Stereotactic Body Radiation Therapy|DRUG: Zirconium Zr 89-Df-Crefmirlimab|RADIATION: Intensity Modulated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Efficacy and Safety of Exenatide Once-Weekly Injection Compared to Once-Daily Insulin in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: exenatide once weekly|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of XW10508 Immediate and Modified Release Formulations in Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: XW10508|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Silodosin, Tadalafil Alone vs. Silodosin Plus Tadalafil as MET for Lower Ureteric Stones
Status: COMPLETED
Conditions: Lower Ureteric Stones|Medical Expulsive Therapy|Tadalafil|Silodosin
Interventions: DRUG: Placebo|DRUG: Silodosin|DRUG: Tadalafil|DRUG: Silodosin and Tadalafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Glutathione (an Antioxidant) and N-Acetylcysteine on Inflammation
Status: COMPLETED
Conditions: Obesity|Hyperlipidemia|Insulin Resistance|Hypertension
Interventions: DIETARY_SUPPLEMENT: Glutathione|DIETARY_SUPPLEMENT: N-Acetylcysteine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Dexmedetomidine Upon Sleep Postoperatively
Status: WITHDRAWN
Conditions: Sleep
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol|DRUG: Midazolam|DRUG: Fentanyl|DRUG: Isoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Open vs. Endoscopic Transversus Abdominis Release Trial
Status: NOT_YET_RECRUITING
Conditions: Incisional Hernia of Midline of Abdomen
Interventions: PROCEDURE: open TAR|PROCEDURE: endoscopic TAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pulsed Radiofrequency in Chronic Lumbosacral Radicular Pain
Status: COMPLETED
Conditions: Lumbar Radiculopathy
Interventions: PROCEDURE: Pulsed radiofrequency on lumbar dorsal root ganglion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT