pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Atezolizumab in Combination With Carboplatin Plus Pemetrexed in Chemotherapy-naïve Patients With Asymptomatic Brain Metastasis
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer Stage IV
Interventions: DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Bioequivalence Study of a Test Tablet Formulation of Ravidasvir With the Reference Tablet Formulation of Ravidasvir Study
Status: COMPLETED
Conditions: Bioequivalence Study
Interventions: DRUG: Ravidasvir test formulation produced by Doppel|DRUG: Ravidasvir reference formulation produced by EEPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LCD Solution Versus Calcipotriol Cream in the Treatment of Moderate Plaque Psoriasis
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis
Interventions: DRUG: LCD|DRUG: calcipotriol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety and Efficacy Study of MT-8554 in Postmenopausal Women With Vasomotor Symptoms
Status: COMPLETED
Conditions: Vasomotor Symptoms (VMS)
Interventions: DRUG: MT-8554
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid Dosing for Major Joint Replacement Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Arthroplasty, Replacement, Knee|Arthroplasty, Replacement, Hip
Interventions: DRUG: Tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Latinx Family Wellness
Status: ACTIVE_NOT_RECRUITING
Conditions: Childhood Obesity
Interventions: BEHAVIORAL: AyuDa Virtual: Aprender y Utilizar Decisiones Apreciables (Spanish) - Learning and Utilizing Significant Choices (English)|BEHAVIORAL: AyuDa Written: Aprender y Utilizar Decisiones Apreciables (Spanish) - Learning and Utilizing Significant Choices (English)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: EBRT and HDR Brachytherapy for Unfavorable-intermediate, High, and Very High-risk Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Prostate Adenocarcinoma
Interventions: RADIATION: External Beam Radiation|RADIATION: HDR Brachytherapy|DRUG: Androgen Deprivation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Virtual Support Intervention for Postnatal Well-being
Status: NOT_YET_RECRUITING
Conditions: Postnatal Depression|Mother-Infant Interaction
Interventions: BEHAVIORAL: Digital Infant- parents support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Alendronate and/or Parathyroid Hormone for Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Human parathyroid hormone [hPTH-(1-34)]|DRUG: alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vadastuximab Talirine (SGN-CD33A; 33A) Combined With Azacitidine or Decitabine in Older Patients With Newly Diagnosed Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: 33A|DRUG: placebo|DRUG: azacitidine|DRUG: decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cesarean Trial of Staples vs. Sutures
Status: COMPLETED
Conditions: Cesarean Section|Wound Complications|Patient Satisfaction|Pain Measurement
Interventions: OTHER: Staples|OTHER: Suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Lactobacillus Reuteri in Adult With Functional Chronic Constipation
Status: COMPLETED
Conditions: Functional Constipation
Interventions: DRUG: lactobacillus reuteri|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder|Depression
Interventions: DRUG: TC-5214|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Corticosteroid Versus Placebo Injection in Patients With Syndesmotic Ligament Injury or High Ankle Sprain
Status: TERMINATED
Conditions: Ankle Injuries
Interventions: DRUG: bupivacaine hydrochloride and betamethasone sodium phosphate|DRUG: bupivacaine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Local Pilocarpine for Relieving Dry Mouth
Status: COMPLETED
Conditions: Patients of Advanced Age (≥ 70 Years) With a Clinical Diagnosis of Chronic Dry Mouth
Interventions: DRUG: Pilocarpine Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Single-arm, Multicenter, Prospective Clinical Study of Mitoxantrone Liposome Combined With Chidamide and Azacitidine in the Treatment of Relapsed and Refractory Peripheral T-cell Lymphoma
Status: UNKNOWN
Conditions: Peripheral T Cell Lymphoma
Interventions: DRUG: Mitoxantrone liposome、Chidamide、Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal Microbiota Transplant
Status: RECRUITING
Conditions: Recurrent Bacterial Vaginosis
Interventions: BIOLOGICAL: Vaginal microbiome transplant|DRUG: Oral Metronidazole|OTHER: Sterile saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness Pain Neuroscience Education In The Executive Functions In Patients With Fibromyalgia
Status: RECRUITING
Conditions: Fibromyalgia|Executive Function|Neuroscience
Interventions: OTHER: Pain Neuroscience Education|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Duloxetine as an Analgesic Agent in Patients Undergoing Elective Spine Surgery
Status: COMPLETED
Conditions: Intervertebral Disc Degeneration
Interventions: DRUG: Duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of a Mobile App on Pregnant Women's Prenatal Genetic Testing Decision-making
Status: UNKNOWN
Conditions: Pregnant Women|Mobile Applications|Genetic Testing|Prenatal Care
Interventions: BEHAVIORAL: Mobile app with prenatal genetic testing information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety Study in Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Dose 4 QD|DRUG: Dose 3 QD|DRUG: placebo|DRUG: Dose 2 QD|DRUG: Dose 1 BD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transfusion of Whole Blood to Military Forces in a Combat Situation
Status: COMPLETED
Conditions: Autologous Blood Transfusion|Physical Performance|Donor Safety
Interventions: PROCEDURE: Whole blood donation and transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PRaG Regimens Rechallenge for Patients With Resistance to PD1/PD-L1 Inhibitors in Refractory Advanced Solid Tumors.
Status: NOT_YET_RECRUITING
Conditions: Metastatic Solid Tumor
Interventions: RADIATION: Hypofractionated radiotherapy|DRUG: PD-L1 inhibitor|DRUG: GM-CSF|DRUG: IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification and Treatment of Diabetes In Solid Organ Transplant Recipients
Status: COMPLETED
Conditions: Complications of Transplanted Organs and Tissue
Interventions: BEHAVIORAL: Psychologist Support|BEHAVIORAL: Pediatric Certified Diabetes Educators (CDEs) Support
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Different Exercise Modalities Training in Patients With Obstructive Sleep Apnea.
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: OTHER: Moderate continuous training (MICT)|OTHER: High intensity interval training (HIIT)|OTHER: Inspiratory muscle training (IMT)|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Online Mindfulness-Based College for Young Adults
Status: UNKNOWN
Conditions: Depressive Symptoms|Loneliness|Sedentary Behavior|Mindfulness|Physical Activity|Diet|Sleep|Emotional Regulation|Alcohol Consumption, Youth|Stress, Psychological
Interventions: BEHAVIORAL: Mindfulness-Based College for Young Adults|OTHER: Health Education for Young Adults
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prophylactic Norepinephrine Infusion for Spinal Hypotension and Inferior Vena Cava Collapsibility Index
Status: COMPLETED
Conditions: Adverse Effect
Interventions: DRUG: normal saline|DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of ACYW135 Group Meningococcal Polysaccharide Conjugate Vaccine (CRM197 Vector) in a 4 to 6 Year-old Population
Status: ACTIVE_NOT_RECRUITING
Conditions: Epidemic Meningitis
Interventions: BIOLOGICAL: MCV4|BIOLOGICAL: MSPV4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Intraarterial Octreotide on Pancreatic Texture
Status: COMPLETED
Conditions: Pancreatic Fistula
Interventions: DRUG: Intraarterial application of Octreotide|DRUG: sterile NaCl (sodium chloride) 0,9% solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Efficacy of Pancreatic Duct Stenting With Rectal Indomethacin in Preventing Post-ERCP Pancreatitis
Status: COMPLETED
Conditions: Post-ERCP Pancreatitis|Pancreatitis, Acute Necrotizing
Interventions: DEVICE: pancreatic duct stenting|DRUG: rectal indomethacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Minoxidil 1% for Eyebrow Enhancement
Status: COMPLETED
Conditions: Eyebrow Hypotrichosis|Thin Eyebrow
Interventions: DRUG: Minoxidil lotion 1%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study Evaluating 12 Versus 24 Weeks Therapy With Peginterferon and Ribavirin for Hepatitis C Virus (HCV) Genotype 2 or 3
Status: COMPLETED
Conditions: Hepatitis C Virus
Interventions: DRUG: Peginterferon alfa-2a 40KD and Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apple Heart Study: Assessment of Wristwatch-Based Photoplethysmography to Identify Cardiac Arrhythmias
Status: COMPLETED
Conditions: Atrial Fibrillation|Arrhythmias, Cardiac|Atrial Flutter
Interventions: DEVICE: Apple Heart Study App
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Nurse-led Care Program for Cancer Patients in Chemotherapy Day Center
Status: COMPLETED
Conditions: Breast Neoplasms|Colorectal Neoplasms
Interventions: BEHAVIORAL: Nurse-led care|BEHAVIORAL: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of LY3200882 and Pembrolizumab in Participants With Advanced Cancer
Status: WITHDRAWN
Conditions: Advanced Cancer
Interventions: DRUG: LY3200882|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pain Reduction After Hemorrhoidectomy With Use of Diltiazim Ointment 2%
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Diltiazem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Monocentric Pilot Study, for a Randomized, Crossover, Blinded Trial: Comparison of the Therapeutic Efficacy of Low Frequency Repeated Transcranial Magnetic Stimulation on Cortical Area 9 Compared to Brodmann Area 46 in the Treatment of Depressive Disorders.
Status: COMPLETED
Conditions: Patients With Resistant Depressive Disorders
Interventions: DEVICE: rTMS BA9/BA46|DEVICE: rTMS BA46/BA9|RADIATION: brain MRI|OTHER: Medical evaluation|OTHER: Psychological assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Depression and Interleukin-6 Production in Patients With Ovarian Epithelial Cancer
Status: WITHDRAWN
Conditions: Depression|Fatigue|Ovarian Cancer|Psychosocial Effects of Cancer and Its Treatment|Sleep Disorders
Interventions: GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis|OTHER: physiologic testing|OTHER: questionnaire administration|PROCEDURE: conventional surgery|PROCEDURE: fatigue assessment and management|PROCEDURE: psychosocial assessment and care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Altitude Related Adverse Health Effects (ARAHE) in Patients With Precapillary Pulmonary Hypertension During 30h Exposure to 2500m
Status: COMPLETED
Conditions: High Altitude Pulmonary Hypertension
Interventions: PROCEDURE: Stay at altitude 2500 m above sea level (high altitude)|PROCEDURE: Stay at altitude 470 m above sea level (low altitude)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Clinical Trial to to Compare of the Efficacy and Safety of Lipilou® 20 mg and Lipilou® 10 mg
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Lipilou®(generic atorvastatin drug) 20 mg|DRUG: Lipilou®(generic atorvastatin drug) 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of the Candidate Rabies Vaccine ChAdOx2 RabG
Status: UNKNOWN
Conditions: Rabies
Interventions: BIOLOGICAL: ChAdOx2 RabG|BIOLOGICAL: Inactivated Rabies Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long Term Extension Study of Ixekizumab (LY2439821) in Participants With Axial Spondyloarthritis
Status: COMPLETED
Conditions: Axial Spondyloarthritis
Interventions: DRUG: Ixekizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Clinical Study of Adebelimumab in Combination With Famitinib and Chemotherapy in Patients With NSCLC
Status: WITHDRAWN
Conditions: NSCLC
Interventions: DRUG: Adebelimumab+Famitinib + FOLFIRI+Ariely
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Distal Nerve Blocks for Closed Reduction of Distal Forearm Fractures
Status: UNKNOWN
Conditions: Fracture Closed of Lower End of Forearm, Unspecified
Interventions: PROCEDURE: Ultrasound guided nerve blocks|PROCEDURE: Hematoma Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sodium Stibogluconate With Interferon Alpha-2b for Patients With Advanced Malignancies
Status: COMPLETED
Conditions: Advanced Cancer|Solid Tumors
Interventions: DRUG: Sodium Stibogluconate|DRUG: Interferon Alpha-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurophysiological Study of Sensory and Cognitive Processes in Healthy Children and Adults
Status: RECRUITING
Conditions: Healthy Volunteer
Interventions: BEHAVIORAL: Neurophysiological assessment|BEHAVIORAL: Neuropsychological assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cardiac Shock Wave Treatment in Patients With Reduced Coronary Flow Reserve
Status: WITHDRAWN
Conditions: Refractory Angina Pectoris|Ischemic Heart Disease|Coronary Artery Disease
Interventions: DEVICE: Cardiac Extracorporeal Shockwave Therapy (Modulith SLC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Tolerability of CKD-508 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: CKD-508 Capsule|DRUG: Placebo Capsule|DRUG: CKD-508 Tablet|DRUG: Placebo Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of RSLV-132 in Subjects With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: RSLV-132
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PF-07321332/Ritonavir and Ritonavir on Dabigatran Study in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Dabigatran|DRUG: PF-07321332/ritonavir + Dabigatran|DRUG: Ritonavir + Dabigatran
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Mindfulness-Based Practices and Deep Relaxation Exercises in Pregnant Women
Status: COMPLETED
Conditions: Anxiety|Pregnancy Related
Interventions: BEHAVIORAL: Mindfullness Based Stress Reduction (MBSR) intervention|BEHAVIORAL: Deep Relaxation Exercises intervention|OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Doctor-Recommended Home-Based Exercise Program or Relaxation Training in Improving Physical Function and Controlling Symptoms in Patients With Stage IV or Recurrent Colon Cancer That Cannot Be Removed By Surgery
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Exercise Program|BEHAVIORAL: Telephone-based intervention|OTHER: Counseling intervention|OTHER: Questionnaire administration|BEHAVIORAL: Relaxation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioequivalence Study of Fluoxetine Hydrochloride Delayed-Release Capsules, 90 mg of Dr. Reddy's Under Fasting Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fluoxetine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Performance of the CytaCoat Lubricious Infection Prevention (LIP) Foley Catheter
Status: RECRUITING
Conditions: Safety of the CytaCoat LIP Foley Catheter|Tolerability of the CytaCoat LIP Foley Catheter
Interventions: DEVICE: Drainage of the bladder by indwelling Foley catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Ophthalmologic Safety Study of Pramipexole Immediate Release (IR) Versus Ropinirole in Early Parkinson's Disease (PD) Patients
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Mirapex|DRUG: Requip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects Of Dynamic Stabilizatıon Exercises And HVLA Manipulatıon in Low Back Paın
Status: NOT_YET_RECRUITING
Conditions: Low Back Pain|Neuromuscular Subluxation of Joint
Interventions: OTHER: Chiropractic Manipulation (HVLA - high velocity low amplitude)|OTHER: Dynamic Neuromuscular Stabilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neurobehavioral Responses to Multisensory Stimulation Module in Preterm Neonates
Status: COMPLETED
Conditions: Preterm Neonates
Interventions: BEHAVIORAL: Multisensory stimulation module
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Stapled TransAnal Rectal Resection (STARR) With Contour® TranstarTM
Status: COMPLETED
Conditions: Obstructed Defecation Syndrome|Rectocele|Intussusception|SNS
Interventions: PROCEDURE: Stapled transanal rectum resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Weight Loss on Hepcidin Levels and Iron Status in Subjects With Obesity.
Status: NOT_YET_RECRUITING
Conditions: Obesity|Iron Deficiency Anemia
Interventions: OTHER: Calorie-restricted diet with red meat|OTHER: Calorie-restricted diet without red meat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extension of a Study of Allogeneic Hematopoietic Stem Cell Transplantation From One Haplotype Mismatch Related Donor or From an Unrelated Donor to Younger Patients Eligible for Reduced-intensity Conditioning Regimen
Status: UNKNOWN
Conditions: Acute Leukemia|Non Hodgkin Lymphoma|Multiple Myeloma
Interventions: PROCEDURE: Hematopoietic stem cells transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tuning in to Kids in School - Competence Building and Collaboration in the Team Around Primary School Students
Status: ENROLLING_BY_INVITATION
Conditions: Healthy
Interventions: BEHAVIORAL: Emotion-focused: Tuning in to Kids in School
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Absorption, Metabolism and Excretion (AME) of Single Dose Radiolabeled Prucalopride Succinate in Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Radiolabeled Prucalopride Succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Double-blind Study Evaluating IPI-504 and Docetaxel in Patients With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: IPI 504 plus Docetaxel|DRUG: Placebo plus Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tryptophan Supplementation to Improve Night Shift Workers' Health
Status: COMPLETED
Conditions: Sleep|Mood|Burnout|Melatonin Deficiency|Cortisol Deficiency
Interventions: DIETARY_SUPPLEMENT: Tryptophan supplement|DIETARY_SUPPLEMENT: Maltose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study of CEA-targeted CAR-T in the Treatment of CEA-positive Advanced Malignant Solid Tumors
Status: RECRUITING
Conditions: Colorectal Cancer|Esophageal Cancer|Stomach Cancer|Pancreatic Cancer|Metastatic Tumor|Recurrent Cancer
Interventions: BIOLOGICAL: CEA CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adenoma Detection Rate in Water and Air Colonoscopy Using Computer-aided System
Status: UNKNOWN
Conditions: Colon Adenoma|Colonoscopy
Interventions: DEVICE: Colonoscopy with water exchange or air insufflation methods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: AMAZ-02 Effect on Exercise ToLerance in Healthy, Overweight Middle Aged Subjects (ATLAS Trial)
Status: COMPLETED
Conditions: Muscle Function, Mitochondrial Function|Overweight|Healthy Aging
Interventions: DIETARY_SUPPLEMENT: Mitopure 500mg|DIETARY_SUPPLEMENT: Mitopure 1000mg|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of the Safety and Efficacy of GDC-0853 in Participants With Moderate to Severe Active Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: GDC-0853|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Herb Drug Interaction of Traditional Chinese Herb and Commonly Used Drugs
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Nalbuphine|DRUG: Morphine|DRUG: Morphine with Long dan xie gan tang|DRUG: Nalbuphine with Long dan xie gan tang|DRUG: Nubian with Long dan xie gan tang
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: The Efficacy and Safety of Once Daily Mexiletine PR in Patients With Myotonic Dystrophy Type 1 and Type 2
Status: NOT_YET_RECRUITING
Conditions: Myotonic Dystrophy
Interventions: DRUG: Mexiletine granules for prolonged-release oral suspension|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxyurea to Prevent Organ Damage in Children With Sickle Cell Anemia
Status: COMPLETED
Conditions: Hematologic Diseases|Anemia, Sickle Cell
Interventions: DRUG: Hydroxyurea|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Induction Therapy With PD-1 Antibody Combined With Platinum-based Doublet Chemotherapy for Locally-advanced Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Locally Advanced|Non-small Cell Lung Cancer
Interventions: DRUG: Serplulimab|DRUG: Carboplatin|DRUG: Pemetrexed|DRUG: Nab-paclitaxel|DRUG: Liposomal paclitaxel|PROCEDURE: Surgery|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selinexor With Alternating Bortezomib or Lenalidomide Plus Dexamethasone in TIE Newly Diagnosed MM Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Selinexor 20 MG Oral Tablet|DRUG: Bortezomib Injection|DRUG: Lenalidomide capsule|DRUG: Dexamethasone Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Pharmacokinetic Interaction of Multiple Dose Ketoconazole on Single Dose YM178 Oral Controlled Absorption System (OCAS) in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Subjects|Pharmacokinetics of YM178
Interventions: DRUG: YM178 OCAS|DRUG: Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Low-dose Gemcitabine and Cisplatin and PD-1/PD-L1 Antibody Therapy in Intrahepatic Cholangiocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma|Chemotherapy Effect|Immunotherapy
Interventions: DRUG: Low-dose Gemcitabine and Cisplatin Chemotherapy plus PD-1/PD-L1Antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Colchicine in Patients at Cardiac Risk Undergoing Major Non-Cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases|Cardiovascular Complication|Perioperative Complication|Myocardial Infarction
Interventions: DRUG: Colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cleaner Air for Better Cardiac Biomarkers
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: OTHER: Portable air cleaner (PAC)|OTHER: Sham Portable air cleaner (PAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Endoscopic Clipping of Diverticula (PECoD)
Status: COMPLETED
Conditions: Diverticular Disease
Interventions: PROCEDURE: Endoscopic clipping|OTHER: Placebo - colonoscopy without clipping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Breathing Exercise With BreatheMAX Device on Airway Secretion Clearance and Lung Function
Status: COMPLETED
Conditions: Bronchial Secretion Retention
Interventions: DEVICE: BreatheMAX (OPEP)|DEVICE: BreatheMAX (OIS and OPEP)|DEVICE: BreatheMAX (unload and non-oscillated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electrical Stimulation for Improving Postoperative Breast Sensation
Status: NOT_YET_RECRUITING
Conditions: Mammaplasty
Interventions: DEVICE: Electrical Stimulation|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Bimodal tDCS on Illness Severity, Insight, Functional Outcomes, Neurocognition and HRV in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Insight Impaired|Psychotic Symptoms|Schizoaffective Disorder|Neurocognitive Dysfunction|Autonomic Imbalance|Psychosocial Impairment|Quality of Life
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of Hemospan® to Prevent Hypotension in Hip Arthroplasty
Status: COMPLETED
Conditions: Hypotension|Ischemia
Interventions: DRUG: Hemospan (MP4OX)|DRUG: Voluven (HES 130/0.4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of a Dolutegravir Dispersible Tablet and Effect of Different Types of Water on the Dispersible Tablet in Healthy Volunteers
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: Dolutegravir Pediatric Granules|DRUG: Dolutegravir Dispersible Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Early iNO for Oxidative Stress, Vascular Tone and Inflammation in Babies With Hypoxic Respiratory Failure
Status: WITHDRAWN
Conditions: Persistent Fetal Circulation Syndrome|Hypertension, Pulmonary, of Newborn, Persistent|Persistent Pulmonary Hypertension of Newborn
Interventions: DRUG: Inhaled nitric oxide|DRUG: Nitrogen Gas|DRUG: Crossover iNO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Verify the Efficacy and Safety of Electric Phlegm Suction System
Status: UNKNOWN
Conditions: Other Specified Respiratory Disorders
Interventions: DEVICE: unmanned electric phlegm suction system procedure using an investigational device (LMECA.A1000)|PROCEDURE: Manual phlegm suction system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery or Capsular Distention With Steroid in the Treatment of Primary Frozen Shoulder?
Status: UNKNOWN
Conditions: Adhesive Capsulitis
Interventions: PROCEDURE: Arthroscopic capsular release|PROCEDURE: Distention with steroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Relative Bioavailability of NKTR-118 in Three Formulations in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: NKTR118 Formulation 1|DRUG: NKTR118 Formulation 2|DRUG: NKTR118 Formulation 3|DRUG: NKTR118 Formulation 1a|DRUG: NKTR118 Formulation 3a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Expanded Access Program for Pirtobrutinib for Participants With B-Cell Cancer
Status: AVAILABLE
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell|Lymphoma, Lymphocytic, Small|Lymphoma, Mantle-Cell|Waldenstrom Macroglobulinemia|Ritcher's Transformation, Syndrome
Interventions: DRUG: Pirtobrutinib
Study Type: EXPANDED_ACCESS
Clinical trial: Trial of Identifying the Lung Intersegmental Plane by Iron Sucrose Injection Staining
Status: COMPLETED
Conditions: Lung Neoplasm|Segmentectomy;Intersegmental Plane
Interventions: DRUG: Iron Sucrose Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mylotarg and Ara-C in Untreated Patients Above 60 Years With AML and High-Risk MDS
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Mylotarg|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Emphysema Using 1.5T MRI With UTE Pulse Sequences
Status: COMPLETED
Conditions: Emphysema
Interventions: OTHER: MR and CT measurements of emphysema quantification
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prone Position Emergence From Anaesthesia in Lumbar Disc Surgery
Status: COMPLETED
Conditions: Haemodynamic Changes During During Emergence|Airway Response During Emergence|Monitor Disconnection During Emergence
Interventions: PROCEDURE: Prone and Supine emergence from anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short and Long Term Outcomes of Doxycycline Versus Trimethoprim-Sulfamethoxazole for Skin and Soft Tissue Infections Treatment
Status: RECRUITING
Conditions: Methicillin-resistant Staphylococcus Aureus|Skin Infection
Interventions: DRUG: TMP-SMX|DRUG: DOXY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimising FSH Dosage During in Vitro Fertilization Fertilization (IVF)
Status: COMPLETED
Conditions: Infertility
Interventions: OTHER: Gonadotropin removal test|OTHER: Routine IVF method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy and Safety of Pantoprazole in Infants With Symptomatic Gastroesophageal Reflux Disease (GERD)
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: pantoprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Fondaparinux in Patients With a Heart Rhythm Disturbance Who Undergo Restoration of Normal Heart Rhythm
Status: COMPLETED
Conditions: Fibrillation, Atrial
Interventions: DRUG: fondaparinux|DRUG: unfractionated heparin|DRUG: Vitamin-K-Antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of 19(T2)28z1xx TRAC-Chimeric Antigen Receptor (CAR) T Cells in People With B-Cell Lymphoma
Status: RECRUITING
Conditions: B-Cell Lymphoma|Large B-cell Lymphoma|DLBCL, Nos Genetic Subtypes|High-grade B Cell Lymphoma|Mediastinal Large B-cell Lymphoma
Interventions: BIOLOGICAL: 19(T2)28z1xx TRAC T cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: Carboplatin|DRUG: Abraxane|DRUG: Abraxane|DRUG: Abraxane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioelectric Field Imaging in Diagnosing Melanoma and Other Skin Cancers in Patients With Skin Lesions
Status: UNKNOWN
Conditions: Melanoma (Skin)|Non-melanomatous Skin Cancer
Interventions: PROCEDURE: bioelectric field imaging|PROCEDURE: biopsy|PROCEDURE: histopathologic examination
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Trial of Aggressive Hydration Versus Rectal Indomethacin for Prevention of Post-ERCP Pancreatitis
Status: COMPLETED
Conditions: Post-ERCP Acute Pancreatitis
Interventions: DRUG: Lactated Ringer|DRUG: Rectal Form Indometacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Does Pulmonary Daoyin of China Give Additional Benefit Over Usual Therapy in Management of Stable Chronic Obstructive Pulmonary Disease?
Status: UNKNOWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: OTHER: Pulmonary daoyin therapy of China|OTHER: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: White Rice and Effect of Gellan Gum on Glucose Responses by MRI
Status: COMPLETED
Conditions: Glycemic Response to Feeding in Healthy Participants
Interventions: DIETARY_SUPPLEMENT: White rice|DIETARY_SUPPLEMENT: Gellan gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Latanoprost on Choroidal Blood Flow Regulation in Human Subjects
Status: COMPLETED
Conditions: Ocular Physiology|Intraocular Pressure|Regional Blood Flow
Interventions: DRUG: Latanoprost 0.005%, Xalatan®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Bioequivalence Study of Guaifenesin and Pseudoephedrine Hydrochloride Extended Release Tablets 1200/120 mg Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Guaifenesin and Pseudoephedrine Hydrochloride Extended Release Tablets 1200/120 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2/3 Study to Evaluate the Efficacy and Safety of CT-P59 in Patients With Mild to Moderate SARS-CoV-2 Infection
Status: COMPLETED
Conditions: SARS-CoV-2 Infection
Interventions: BIOLOGICAL: CT-P59|BIOLOGICAL: CT-P59|BIOLOGICAL: Placebo|BIOLOGICAL: CT-P59|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemoradiation With Cisplatin Every 3 Week in Advanced Cervical Cancer
Status: COMPLETED
Conditions: CERVICAL NEOPLASMS
Interventions: DRUG: CONCURRENT CHEMORADIATION (CISPLATIN)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Animal Assisted Activities on the Stress and Social Anxiety
Status: COMPLETED
Conditions: Stress|Social Anxiety|Disabling Disease|Animal Communication|Nursing Caries|Child
Interventions: OTHER: Animal Assisted Activity Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rudi Kundini, Pamoja Kundini: Phase I
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV (Human Immunodeficiency Virus)
Interventions: BEHAVIORAL: Conditional Cash Transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Post Operative Pain of Root Canal Preparation With Wave One and Neolix in Acute Irreversible Pulpitis
Status: UNKNOWN
Conditions: Pulpitis - Irreversible
Interventions: PROCEDURE: neolix|PROCEDURE: wave one
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immobilization After an Anterior Glenohumeral Joint Dislocation With a Bankart Lesion
Status: UNKNOWN
Conditions: Glenohumeral Joint Dislocation
Interventions: DEVICE: Donjoy ER brace|DEVICE: Thoraco brachial brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: gliomasPCV Only in 1p/19q Codeleted Anaplastic Gliomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Anaplastic Gliomas With 1p/19q Codeletion
Interventions: DRUG: PCV chemotherapy alone|DRUG: Radiotherapy+PCV chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maxillary Expansion Effects in Children With Upper Airway Obstruction
Status: UNKNOWN
Conditions: Airway Obstruction
Interventions: PROCEDURE: Rapid maxillary expansion|PROCEDURE: Adenotonsillectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fatty Liver Disease in Obese Children
Status: COMPLETED
Conditions: Obesity|Nonalcoholic Fatty Liver Disease|Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: N-acetyl cysteine 600 mg once/day|DIETARY_SUPPLEMENT: N-acetyl cysteine 600mg twice/day|OTHER: Placebo twice/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: C11-Acetate PET/CT in Multiple Myeloma: Added Value to F18-Fluorodeoxyglucose PET/CT
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: OTHER: ACT PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of Keratoconus With Advanced CXL-II
Status: UNKNOWN
Conditions: Keratoconus
Interventions: PROCEDURE: Topography-based CXL (KXL2)|PROCEDURE: Conventional pulsed CXL (pCXL)|DRUG: Riboflavin|DEVICE: Avedro KXL II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine vs. S-1 in Unresectable or Recurrent Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Capecitabine|DRUG: S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating Cardiovascular Adverse Events Related to Cancer Treatment
Status: RECRUITING
Conditions: Toxicity Due to Chemotherapy|Cardiovascular Morbidity|Cancer, Treatment-Related
Interventions: DRUG: Anthracyclines|DRUG: Trastuzumab|DRUG: Cisplatin|DRUG: Bleomycin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p