pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Does Strepsils® With Lignocaine Lozenges Reduce Post Operative Sore Throat Due To Supraglottic Airway Devices
Status: COMPLETED
Conditions: Sore Throat|Post Operative Sore Throat
Interventions: DRUG: Strepsils Anaesthetic Formula|DIETARY_SUPPLEMENT: Clear Mint Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bendamustine Hydrochloride Injection for Previously Untreated Chronic Lymphocytic Leukemia
Status: UNKNOWN
Conditions: Chronic Lymphocytic Leukemia|Leukemia|Neoplasms
Interventions: DRUG: Bendamustine Hydrochloride Injection|DRUG: Chlorambucil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Tazemetostat in Solid Tumors Harboring an ARID1A Mutation
Status: RECRUITING
Conditions: Solid Tumor|ARID1A Gene Mutation
Interventions: DRUG: Tazemetostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Adalimumab in Subjects With Moderate to Severe Chronic Hidradenitis Suppurativa
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: BIOLOGICAL: adalimumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Limbal Astigmatic Keratotomy to Correct High Degrees of Astigmatism After Phacoemulsification
Status: COMPLETED
Conditions: Astigmatism
Interventions: PROCEDURE: manual astigmatic keratotomy|PROCEDURE: femtosecond laser astigmatic keratotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessing Outcomes of Enhanced Chronic Disease Care Through Patient Education and a Value-based Formulary Study
Status: COMPLETED
Conditions: Coronary Disease|Stroke|Chronic Kidney Disease|Heart Failure|Diabetes Mellitus|Hypertension|Hypercholesterolemia
Interventions: BEHAVIORAL: Copayment Elimination|BEHAVIORAL: Personalized Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tislelizumab Combined Treatment in Refractory Extranodal NK/T-cell Lymphoma
Status: COMPLETED
Conditions: Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type
Interventions: DRUG: tislelizumab, azacytidine, lenalidomide|DRUG: tislelizumab, etoposide, pegaspargase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiotherapy for Persistent Function by Superficial Neuromodulation
Status: RECRUITING
Conditions: Post-Acute COVID-19 Syndrome|Dysautonomia|Neuromodulation
Interventions: DEVICE: Neuromodulation NESA NXSIGNAL® device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bronchodilating Effects of Formoterol When Administered Via Symbicort Pressurized Metered-dose Inhaler (pMDI) or Oxis Turbuhaler
Status: COMPLETED
Conditions: Stable Asthma
Interventions: DRUG: budesonide/formoterol|DRUG: formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Changes in CSF Ionic Composition After Aneurysmal Meningeal Hemorrhage
Status: RECRUITING
Conditions: Subarachnoid Hemorrhage
Interventions: OTHER: Concurrent evaluation of blood and CSF ionograms to determine if there is a correlation between CSF change and the development of hyoponatremia between day 0 and day 14.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Investigation of Antimycobacterial Therapy on Progressive, Pulmonary Sarcoidosis
Status: COMPLETED
Conditions: Sarcoidosis; Antimycobacterial Therapy
Interventions: DRUG: Levofloxacin|DRUG: Ethambutol|DRUG: Azithromycin|DRUG: Rifampin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nighttime Agitation and Restless Legs Syndrome in People With Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer Disease
Interventions: DRUG: Gabapentin Enacarbil|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Intervention Study to Promote Functional Health in Women
Status: NOT_YET_RECRUITING
Conditions: Health Behavior
Interventions: BEHAVIORAL: Guided Imagery|BEHAVIORAL: Cognitive Power Intervention|BEHAVIORAL: Combined Guided Imagery and Cognitive Power Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Ascending Single- and Multiple-Doses of TAK-020 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-020|DRUG: TAK-020 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Lenvatinib (MK-7902) in Pediatric Participants With Relapsed or Refractory Solid Malignancies (MK-7902-013/E7080)
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed or Refractory Solid Tumors
Interventions: DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Self-Acupressure Application on Functional Composite and Quality of Life in Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: Self-Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Continuous Erector Spinae Plane Blocks to Treat Postoperative Pain After Open Gynecologic Procedures Via a Low Transverse (Pfannenstiel) Incision
Status: WITHDRAWN
Conditions: Surgical Incision|Pain, Postoperative|Pain, Acute
Interventions: DRUG: Bupivacaine 0.25%|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of HRS-5965 in Healthy Subjects and Subjects With Renal Insufficiency
Status: RECRUITING
Conditions: Glomerulonephritis
Interventions: DRUG: HRS-5965|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sub-study of the NEURODOC Project : Neurophysiological Evaluation of a Routine Care Open Label tDCS Session
Status: COMPLETED
Conditions: Disorder of Consciousness|Traumatic Brain Injury|Anoxic Brain Injury|Stroke
Interventions: BEHAVIORAL: Coma Recovery Scale - revised|DIAGNOSTIC_TEST: Electrophysiological recordings
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Vibrating Mesh Versus Small Volume Nebuliser in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|COPD|Copd Exacerbation Acute|COPD Exacerbation
Interventions: DEVICE: Vibrating Mesh Nebuliser|DEVICE: Standard Hospital Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hydrodynamic Parameters on Corneal Endothelial Cell Loss After Phacoemulsification
Status: COMPLETED
Conditions: Cataract
Interventions: PROCEDURE: phacoemulsification using either high vacuum or low vacuum techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Chemoprophylaxis Plus Early Ambulation
Status: COMPLETED
Conditions: Pulmonary Embolism|Thoracic Surgery
Interventions: DRUG: Chemoprophylaxis with Low Molecular Weight Heparin (LMWH)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Integrating Text Messages Into the Mothers and Babies Course
Status: COMPLETED
Conditions: Perinatal Depression|Postpartum Depression
Interventions: BEHAVIORAL: Mothers and Babies 1-on-1|BEHAVIORAL: Mothers and Babies Plus Text
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Diagnostic Test of Choice for HELPS Syndrome
Status: COMPLETED
Conditions: HELPS Syndrome
Interventions: DIAGNOSTIC_TEST: Pre-Operative CISS-MRI Sequences|DIAGNOSTIC_TEST: Pre-Operative Interictal Laryngoscopy|DIAGNOSTIC_TEST: Pre-Operative Unilateral and Contralateral Botox
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Complementary Therapies Delivered Via Mobile Technologies
Status: COMPLETED
Conditions: Acute Pain|Anxiety|Self Efficacy
Interventions: BEHAVIORAL: Audio Relaxation Technique|BEHAVIORAL: Medical Music Intervention|BEHAVIORAL: Nature Therapy without Music|BEHAVIORAL: Nature Therapy with Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Pilot Study to Determine Optimal Procedure Steps to Obtain and Maintain Uterine Artery Occlusion With the D-UAO Device
Status: TERMINATED
Conditions: Uterine Fibroids
Interventions: DEVICE: GYNECARE GYNOCCLUDE™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Confronting Unequal Eye Care in Pennsylvania
Status: COMPLETED
Conditions: Diabetic Retinopathy|Diabetes Mellitus, Type 2|Glaucoma
Interventions: BEHAVIORAL: Behavioral Activation|BEHAVIORAL: Supportive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Wound Infiltration With Tramadol, Dexmedetomidine, or Magnesium Plus Ropivacaine for Pain Relief After Spine Surgery
Status: COMPLETED
Conditions: Analgesia|Pain, Postoperative|Spinal Stenosis|Spinal Disease
Interventions: DRUG: Tramadol with ropivacaine|DRUG: Dexmedetomidine with ropivacaine|DRUG: Magnesium with ropivacaine|DRUG: Ropivacaine plus normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Gemcitabine and Docetaxel Combination Chemotherapy in Patients With Carcinoma of Unknown Primary
Status: UNKNOWN
Conditions: Carcinoma of Unknown Primary
Interventions: DRUG: gemcitabine/docetaxel combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infusion of Umbilical Cord Versus Bone Marrow Derived Mesenchymal Stem Cells to Evaluate Cytokine Suppression.
Status: TERMINATED
Conditions: Endothelial Dysfunction|Metabolic Syndrome|Chronic Inflammation
Interventions: BIOLOGICAL: UCMSCs|BIOLOGICAL: BMMSCs|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ICP-189 and ICP-189 in Combination With Anti-PD-1 Monoclonal Antibody in Patients With Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Patients With Advanced Solid Tumors
Interventions: DRUG: ICP-189
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Light Delivery Method for Performing Transbronchial Photodynamic Therapy for Peripheral Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer|Lung Cancer Metastatic
Interventions: PROCEDURE: Transbronchial PDT peripheral lung tumor ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Antacid and Multivitamin and Mineral Tablet on the Study Drug GSK1349572
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: GSK1349572 and MaaloxAdvanced Maximum Strength|DRUG: GSK1349572 and Maalox Advanced Maximum Strength|DRUG: GSK1349572 and One A Day|DRUG: GSK1349572
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Dose Response to Recombinant Factor VIIa When Administered for Bleed
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Healthy
Interventions: DRUG: activated recombinant human factor VII
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study in Chinese Healthy Adults to Evaluate the Safety, Tolerability and Pharmacokinetics on ZSP0678, and the Effect of Food on ZSP0678 Pharmacokinetics
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: ZSP0678-10mg|DRUG: ZSP0678-30mg|DRUG: ZSP0678-60mg|DRUG: ZSP0678-120mg|DRUG: ZSP0678-180mg|DRUG: ZSP0678-240mg|DRUG: ZSP0678-320mg|DRUG: ZSP0678|DRUG: ZSP0678-Dose 1|DRUG: ZSP0678-Dose 2|DRUG: ZSP0678-Dose 3|DRUG: ZSP0678 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Basal-like PDAC Treated With Gemcitabine, Erlotinib, and Nab-paclitaxel
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Adenocarcinoma|Metastatic Pancreatic Cancer|Basal Cell Neoplasm
Interventions: DRUG: Gemcitabine|DRUG: Nab paclitaxel|DRUG: Erlotinib|DRUG: NALIRIFOX|DRUG: Folfirinox
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Immune Response of Heterologous Boost Third Dose of mRNA and Protein COVID-19 Vaccine
Status: UNKNOWN
Conditions: COVID-19|Breakthrough Infection
Interventions: BIOLOGICAL: BNT162b2|BIOLOGICAL: mRNA-1273|BIOLOGICAL: MVC-COV1901
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Needlescopic Inversion and Snaring of Hernia in Girls
Status: COMPLETED
Conditions: Inguinal Hernia|Polyps|Fallopian Tube Injury|Round Ligament; Anomaly
Interventions: DEVICE: Inversion and snaring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mass Practice of Activities of Daily Living in Dementia (STOMP)
Status: COMPLETED
Conditions: Dementia|Alzheimer's Disease
Interventions: BEHAVIORAL: STOMP (Skill-building through Task-Oriented Motor Practice)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Prescription Omega-3 Fatty Acid Added to Stable Statin Therapy in Patients With Type 2 Diabetes and Hypertriglyceridemia
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Hypertriglycemia
Interventions: DRUG: Omega-3-acids ethylesters 90 4g|DRUG: Pravastatin, Simvastatin, Atorvastatin, Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation Study in MS Patients
Status: TERMINATED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Interferon beta-1b, FRP within 15 days after randomization|DRUG: Interferon beta-1b, FRP about 6 weeks after randomization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Targeted-therapy for Patients With Resected High-risk EGFR-mutant Stage IB-IIA Non-small Cell Lung Carcinoma
Status: RECRUITING
Conditions: NSCLC|EGF-R Positive Non-Small Cell Lung Cancer
Interventions: DRUG: Furmonertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Ultrasound-guided Modified Pectoral Nerves Block Versus Ketamine Plus Magnesium Infusion On Analgesic Profile In Breast Cancer Surgeries
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: PROCEDURE: pectoral nerves block group|DRUG: Ketamine plus magnesium group|DRUG: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Mometasone Furoate Dry Powder Inhaler, Fluticasone Propionate, and Montelukast on Bone Mineral Density in Asthmatics (Study P03418)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: mometasone furoate dry powder inhaler|DRUG: mometasone furoate dry powder inhaler|DRUG: fluticasone propionate hydrofluoroalkane (HFA)|DRUG: montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Aleglitazar in Patients With Type 2 Diabetes Mellitus Who Have Not Previously Received Anti-Hyperglycemic Therapy
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Placebo|DRUG: aleglitazar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Immunogenicity of HIV-1 BG505 SOSIP.664 gp140 With TLR Agonist and/or Alum Adjuvants in Healthy, HIV-uninfected Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections
Interventions: BIOLOGICAL: BG505 SOSIP.664 gp140|BIOLOGICAL: Placebo|BIOLOGICAL: 3M-052-AF|BIOLOGICAL: CpG 1018|BIOLOGICAL: GLA-LSQ|BIOLOGICAL: Alum (Aluminum Hydroxide Suspension)|BIOLOGICAL: Trimer 4571
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination of Radiation Therapy and Peptide Specific CTL Therapy in Treating Patients With Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Neoplasms|Esophageal Diseases|Digestive System Diseases
Interventions: BIOLOGICAL: peptide specific CTL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk-stratified Therapy Based on Molecular Cytogenetic Aberration and Treatment Response in AML
Status: UNKNOWN
Conditions: Risk-directed Therapy|Cytogenetic Abnormality|Molecular Abnormality|MRD
Interventions: OTHER: Justified risk stratification based on MRD after three course chemo therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 2 Dasatinib Combo With Smoothened (SMO) Antagonist (BMS-833923)
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: Dasatinib|DRUG: BMS-833923
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peginterferon Alpha-2b Therapy in Chronic Hepatitis Patients With Normal ALT Level and Low Viremia
Status: UNKNOWN
Conditions: Chronic Hepatitis B Patients With a Normal ALT Level and Low Viremia
Interventions: DRUG: Peginterferon alpha-2b|DRUG: Nucleotide Analog|DRUG: pulse peginterferon alpha-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact on Ovarian Reserve According to the Type of Ovarian Endometrioma Excision: Laser Versus Conventional Cystectomy
Status: COMPLETED
Conditions: Endometriosis Ovary
Interventions: PROCEDURE: CO2 (carbon dioxide) laser vaporisation|PROCEDURE: Stripping technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Erector Spinae Plane Block Versus Quadratus Lumborum Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: OTHER: Group Erector Spinae Plane Block (ESPB)|OTHER: Group Quadratus Lumborum Block (QLB)|OTHER: Group (C) (Control group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Motor Learning After Cerebellar Damage: The Role of the Primary Motor Cortex
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebellar Ataxia
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fasting Study of Liothyronine Sodium Tablets (50 Mcg) to Cytomel® Tablets (50 Mcg)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 1: Liothyronine Sodium Tablets|DRUG: 2: Cytomel® Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Cardioneuroablation in Reflex Syncope (CARDIOSYRE Trial)
Status: RECRUITING
Conditions: Reflex Syncope
Interventions: PROCEDURE: cardioneuroablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Examine the Longer-Term Efficacy and Safety of Sibutramine Hydrochloride in Obese Subjects
Status: TERMINATED
Conditions: Obesity|Weight Loss
Interventions: DRUG: placebo|DRUG: sibutramine or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: STARS (Smoking Treatment And Remote Sampling) Study
Status: RECRUITING
Conditions: Smoking|Smoking Cessation|Tobacco Smoking|Cigarette Smoking
Interventions: DRUG: Varenicline 0.5 MG|DRUG: Nicotine Replacement Therapy (NRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Artificial Intelligence-assisted Colonoscopy on Detection of Missed Proximal Lesions
Status: COMPLETED
Conditions: Colon Adenoma|Colon Polyp
Interventions: DEVICE: Artificial intelligence-Assisted colonoscopy|PROCEDURE: Conventional colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Dapagliflozin Effect on Erythropoiesis and Physical Fitness
Status: WITHDRAWN
Conditions: Type 2 Diabetes Mellitus (T2DM)
Interventions: DRUG: Dapagliflozin (Forxiga®)|DRUG: Hydrochlorothiazide 25 mg|DRUG: Placebo matching Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Nicotine Cigarettes, Smoking, and Chronic Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain|Smoking, Cigarette
Interventions: OTHER: SPECTRUM NRC 102/103 investigational cigarettes|OTHER: SPECTRUM NRC 600/601 investigational cigarettes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Caregiver Stress and Sleep Study
Status: RECRUITING
Conditions: Depressive Symptoms|Caregiver Burden
Interventions: BEHAVIORAL: Morning Action Plan Execution|BEHAVIORAL: Activity Strategy-based Session with Therapist|BEHAVIORAL: Attention-based Session with Therapist|BEHAVIORAL: Advance sleep-wake time
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Young Adults with Violent Behavior During Early Psychosis
Status: RECRUITING
Conditions: Schizophrenia|Schizo Affective Disorder|Schizophreniform Disorders|Delusional Disorder|Other Specified Schizophrenia Spectrum and Other Psychotic Disorder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: Early Test-of-cure
Status: COMPLETED
Conditions: African Trypanosomiasis|African; Trypanosomiasis, West|Sleeping Sickness; West African|Trypanosoma Brucei Gambiense; Infection
Interventions: DIAGNOSTIC_TEST: RNA and neopterin detection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study of Vitamin D Supplementation in Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Cholecalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prebiotic Fructans on the Incidence of Acute Infectious Diseases in Children
Status: COMPLETED
Conditions: Infectious Disease|Children, Only|Diet Modification
Interventions: DIETARY_SUPPLEMENT: prebiotic inulin-type fructan|DIETARY_SUPPLEMENT: Placebo maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Using Long Acting Antihistamine to Treat Opioid Induced Itching
Status: TERMINATED
Conditions: Pruritus
Interventions: DRUG: Cetirizine|DRUG: Placebo or sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Histopathologic Characteristics of BAP1 Mutations
Status: COMPLETED
Conditions: Malignant Pleural Mesothelioma (MPM)|Choroidal Nevus|Primary Uveal Melanoma (UM)|Metastatic Uveal Melanoma (UM)|Renal Cell Carcinoma|Cholangiocarcinoma
Interventions: OTHER: tumor specimens
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission
Status: RECRUITING
Conditions: HIV Infection
Interventions: DRUG: Nucleoside Reverse Transcriptase Inhibitors (NRTIs)|DRUG: Nevirapine (NVP)|DRUG: Lopinavir/Ritonavir (LPV/r)|DRUG: Raltegravir (RAL)|DRUG: VRC01|DRUG: DTG|DRUG: VRC07-523LS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Definition Colonoscopy (HDC) vs. Dye Spraying Chromo-colonoscopy (DSC) in Screening Patients With Long-standing Inflammatory Bowel Disease (IBD)
Status: ENROLLING_BY_INVITATION
Conditions: Inflammatory Bowel Diseases|Colon Dysplasia|Ulcerative Colitis|Crohn Colitis|Indeterminate Colitis
Interventions: DEVICE: High Definition Colonoscopy|DEVICE: Dye Spraying Chromocolonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Attention Deficit Hyperactivity Disorder (ADHD) Smoking Cessation Study
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Nicotine Dependence
Interventions: DRUG: Transdermal Nicotine Patch|DRUG: Lis-dexamphetamine (Vyvanse)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fish Oil in pREgnancY for Personalized Prevention of Early Childhood Asthma
Status: NOT_YET_RECRUITING
Conditions: Asthma|Respiratory Tract Infections|Gastrointestinal Infection|Croup|Eczema|Allergy|Wheezing|Fractures, Bone|Development, Child|Cognition Disorders in Children|Psychiatric Diagnosis
Interventions: DIETARY_SUPPLEMENT: n-3 fatty acid|OTHER: Rape seed oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Functional Testing Underlying Coronary Revascularisation
Status: COMPLETED
Conditions: Multivessel Coronary Artery Disease|Vessel Disease|Stable Angina|Unstable Angina or Stabilized Non-ST Elevated Myocardial Infarction|Patients With ST-elevated Myocardial Infarction|Revascularization of Culprit Coronary Artery
Interventions: PROCEDURE: invasive coronary angiography|PROCEDURE: Functional testing by fractional flow reserve measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Responses to Live Attenuated Influenza Virus (LAIV) in Chronic Obstructive Pulmonary Disease (COPD)
Status: RECRUITING
Conditions: COPD
Interventions: BIOLOGICAL: LAIV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Surgical Debulking Prior to Peptide Receptor Radionuclide Therapy in Well Differentiated Gastroenteropancreatic Neuroendocrine Tumors
Status: RECRUITING
Conditions: Digestive System Neuroendocrine Tumor G1|Digestive System Neuroendocrine Tumor G2|Metastatic Digestive System Neuroendocrine Neoplasm|Metastatic Malignant Neoplasm in the Liver|Pancreatic Neuroendocrine Tumor G1|Pancreatic Neuroendocrine Tumor G2
Interventions: PROCEDURE: Tumor Debulking|DRUG: Lutetium Lu 177 Dotatate|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Copper Cu 64 Dotatate|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Traditional Chinese Medicine on Ameliorating IVF-ET Outcomes of Diminished Ovarian Reserve Patients
Status: NOT_YET_RECRUITING
Conditions: Diminished Ovarian Reserve|Infertility, Female
Interventions: DRUG: Medical prescription before ovulation|DRUG: Medical prescription after ovulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of Tolerance, Biodistribution and Dosimetry of Fucoidan Radiolabeled by Technetium-99m
Status: UNKNOWN
Conditions: Healthy Volunteer
Interventions: DRUG: 99mTc-Fucoidan SPECT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: P.A.R.Q.V.E III - Comparison of the Educational Program With and Without Multidisciplinary Care
Status: UNKNOWN
Conditions: Osteoarthritis|Metabolic Diseases
Interventions: BEHAVIORAL: Womac|BEHAVIORAL: Lequesne|BEHAVIORAL: Numerical Rating Scales (NRS)|BEHAVIORAL: IPAQ|BEHAVIORAL: STS30|BEHAVIORAL: TUG|BEHAVIORAL: Six-minute Test|BEHAVIORAL: Two days of lectures|BEHAVIORAL: Session with the psychologists|BEHAVIORAL: Sessions with the physical therapy team|BEHAVIORAL: Sessions with the physical educators team|BEHAVIORAL: Nutritional habits to be improved|BEHAVIORAL: Tampa Scale for Kinesiophobia (TSK)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, PK, and PD of LIM-0705 in Subjects With Impaired Glucose Tolerance or Abnormal HOMA-IR
Status: UNKNOWN
Conditions: Impaired Glucose Tolerance|Insulin Resistance
Interventions: DRUG: LIM-0705|DRUG: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Testing the Effect of KnowMAP (Knowledge Management for Renal Transplant Recipients). A Randomized Controlled Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Transplantation
Interventions: OTHER: Motivational interview as a new health communication intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Study on the Efficacy and Safety of HBM9161 in Patients With ITP
Status: UNKNOWN
Conditions: Primary Immune Thrombocytopenic Purpura
Interventions: DRUG: HBM9161 Dose A|DRUG: HBM9161 Dose B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effects of Fish Protein Intake on Glucose Regulation in Overweight and Obese Adults.
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DIETARY_SUPPLEMENT: Salmon protein hydrolysate|DIETARY_SUPPLEMENT: Herring protein hydrolysate|DIETARY_SUPPLEMENT: Cod protein|DIETARY_SUPPLEMENT: Milk protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: S095029 as Monotherapy and in Combination With Sym021 in Patients With Advanced Solid Tumor Malignancies Followed by an Expansion Part With Triple Combinations in Patients With Metastatic Gastric or Colorectal Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: S095029|DRUG: S95029 and Sym021|DRUG: S095029 and Sym021 and anti-HER2 therapy|DRUG: Dose expansion 2b: S095029 and Sym021 and futuximab/modotuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Access Program Using Alpha 1 Antitrypsin Infusion for Patients With Steroid Refractory Acute GvHD After Hematopoietic Stem Cell Transplantation (HSCT)
Status: NO_LONGER_AVAILABLE
Conditions: Acute-graft-versus-host Disease|Steroid Refractory Acute Graft Versus Host Disease|Graft-versus-host-disease|Graft Vs Host Disease|Alpha 1-Antitrypsin Deficiency|Alpha-1 Proteinase Inhibitor|Alpha-1 Protease Inhibitor Deficiency|Acute Graft-Versus-Host Reaction Following Bone Marrow Transplant
Interventions: DRUG: Glassia
Study Type: EXPANDED_ACCESS
Clinical trial: Sequential Use of Propofol/Midazolam and Dexmedetomidine for Sedation in Mechenical Ventialtion Patients in ICU.
Status: UNKNOWN
Conditions: Mechanical Ventilation Complication
Interventions: DRUG: Fentanyl|PROCEDURE: Sedation assessment|PROCEDURE: Screen of weaning|DRUG: Propofol|DRUG: Midazolam|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT: Fentanyl Plus Ketamine Versus Fentanyl Alone for Acute Burn Pain
Status: TERMINATED
Conditions: Acute Pain|Wound Care|Posttraumatic Stress Disorder
Interventions: DRUG: ketamine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Multicenter Registry of Hybrid Coronary Artery Revascularization Combined With Surgical Bypass and Percutaneous Coronary Intervention Using Everolimus Eluting Metallic Stents
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Coronary artery bypass grafting|PROCEDURE: Percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Marine Based Nutritional Supplement Peptidyss® on Sleep and Anxiety
Status: COMPLETED
Conditions: Sleep Disorder
Interventions: DIETARY_SUPPLEMENT: Fish Hydrolysate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of Current Biomarker Testing Practices for Common Solid Cancers in Precision Oncology in the Community Setting
Status: WITHDRAWN
Conditions: Breast Carcinoma|Colorectal Carcinoma|Community Practice|Lung Carcinoma|Melanoma|Solid Neoplasm
Interventions: OTHER: Survey Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hemodynamic Assessment of Mosaic Ultra Stented Heart Valve in the Aortic Position
Status: COMPLETED
Conditions: Aortic Valve Replacement|Coronary Artery Bypass Grafting
Interventions: DEVICE: Aortic implantation of Mosaic Ultra porcine bioprosthesis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analgesic Efficacy and Safety Study of Naproxcinod in Subjects With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Placebo|DRUG: Naproxcinod 375 mg|DRUG: Naproxen|DRUG: Naproxcinod 750 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Derivation of a Clinical Prediction Rule to Identify Those With Low Back Pain Who Will Respond Favorably to Intramuscular Dry-needling
Status: RECRUITING
Conditions: Low Back Pain
Interventions: OTHER: Intramuscular Dry-Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vistusertib (AZD2014) Monotherapy in Relapsed Small Cell Lung Cancer Patients Harboring RICTOR Amplification
Status: TERMINATED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: vistusertib (AZD2014)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thymoglobulin Versus Alemtuzumab Versus Daclizumab in Living Donor Renal Transplantation
Status: COMPLETED
Conditions: End-Stage Renal Disease|Living Donors
Interventions: DRUG: Anti-Thymocyte Globulin vs Campath-1H vs Daclizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Usefulness of Doppler Ultrasound Carried Out by the Vascular Surgeon After Loco-regional Anesthesia for Preferred Access
Status: COMPLETED
Conditions: Arterio-venous Fistula
Interventions: DIAGNOSTIC_TEST: Duplex ultrasound performed by the surgeon after locoregional anesthesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Regulatory Post Marketing Surveillance (rPMS) Study of Ryzodeg® FlexTouch® (Insulin Degludec /Insulin Aspart) to Evaluate Safety and Effectiveness in Patients With Diabetes Mellitus in Routine Clinical Practice in Korea
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin degludec /insulin aspart
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Therapy of Interleukin-12 and Interleukin-2 to Treat Advanced Cancer
Status: TERMINATED
Conditions: Kidney Neoplasm|Lung Neoplasm|Sarcoma|Breast Neoplasm
Interventions: BIOLOGICAL: rh IL-12|BIOLOGICAL: rh IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Airway Clearance Therapy in Non-cystic Fibrosis Bronchiectasis
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: OTHER: Chest physiotherapy plus usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Two Anti-HIV Drug Combinations on the Immune Systems of HIV-Infected Patients Who Have Never Received Anti-HIV Drugs
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lopinavir/Ritonavir|DRUG: Abacavir sulfate|DRUG: Nevirapine|DRUG: Lamivudine|DRUG: Stavudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Depo-Medrol on Psoas After LLIF
Status: RECRUITING
Conditions: Muscle Weakness|Pain, Postoperative|Paresthesia|Pain, Muscle
Interventions: DRUG: Depo-Medrol|DRUG: Gel-Flow NT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Trial- Dysphagia From ETT or GI Endoscopy
Status: WITHDRAWN
Conditions: Dysphagia|Respiratory Complications
Interventions: DEVICE: endotracheal tube|DRUG: propofol|DRUG: Fentanyl|DRUG: Dexamethasone|DRUG: Ondansetron|DRUG: sevoflurane, nitrous oxide and oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: CS-7017 in Combination With Carboplatin/Paclitaxel in Subjects With Stage IIIb/IV Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: CS-7017|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Immunostimulating Nutrition on the Outcome of Surgery
Status: COMPLETED
Conditions: Gastric Cancer|Pancreatic Cancer
Interventions: DRUG: peptisorb|DRUG: Stresson|DRUG: Parenteral nutrition|DRUG: Omegaven, Dipeptiven
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of an Anti-cancer Drug, Berzosertib, to the Usual Treatment (Radiation Therapy) for Chemotherapy-Resistant Triple-Negative and Estrogen and/or Progesterone Receptor Positive, HER2 Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Bilateral Breast Carcinoma|HER2-Negative Breast Carcinoma|Localized Breast Carcinoma|Recurrent Breast Carcinoma|Triple-Negative Breast Carcinoma
Interventions: DRUG: Berzosertib|PROCEDURE: Biospecimen Collection|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Effects of an AMP Challenge on Asthmatic Patients Following Treatment With Fluticasone Propionate
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pureed Rice Using a Gelling Agent and Standard Pureed Rice
Status: COMPLETED
Conditions: Swallowing Disorder
Interventions: OTHER: a gelling agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Evaluating the Impact on Fat Distribution of Nucleoside Reverse Transcriptase Inhibitor (NRTI)-Sparing Regimens in Antiretroviral Experienced Patients With Lipoatrophy
Status: TERMINATED
Conditions: HIV Infections|HIV Lipodystrophy Syndrome
Interventions: DRUG: non-nucleoside reverse transcriptase inhibitors|DRUG: nucleoside reverse transcriptase inhibitors|DRUG: protease inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Limb Preconditioning In Healthy Volunteers
Status: COMPLETED
Conditions: Cerebrovascular Disease|Stroke
Interventions: PROCEDURE: 4x 5min Limb Preconditioning|PROCEDURE: 3x 10min Limb Preconditioning|PROCEDURE: 3x 10min Sham Preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Corneal Scars
Status: RECRUITING
Conditions: Corneal Scar
Interventions: BIOLOGICAL: CSB-001 Ophthalmic Solution 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paraffin Oil or Coconut Oil in Acute Aluminum Phosphide Poisoning
Status: COMPLETED
Conditions: Aluminum Phosphide Poisoning
Interventions: OTHER: gastric lavage with paraffin oil and bicarbonate|OTHER: gastric lavage with coconut oil and bicarbonate|DRUG: standard treatment|OTHER: gastric lavage with saline and bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long COVID Immune Profiling
Status: RECRUITING
Conditions: Long COVID|POTS - Postural Orthostatic Tachycardia Syndrome|Autonomic Dysfunction
Interventions: DIAGNOSTIC_TEST: IL-6|DIAGNOSTIC_TEST: cytokines (IL-17, and IFN-ɣ)|BEHAVIORAL: Compass 31
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Autologous Fat Grafting With PRP (Platelet Rich Plasma) to Anophthalmic Sockets
Status: COMPLETED
Conditions: Orbital Atrophy
Interventions: PROCEDURE: autologous fat grafting with PRP to anophthalmic orbits
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VEGF Trap in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Ciliary Body and Choroid Melanoma, Medium/Large Size|Extraocular Extension Melanoma|Iris Melanoma|Metastatic Intraocular Melanoma|Recurrent Intraocular Melanoma|Recurrent Melanoma|Stage III Melanoma|Stage IV Melanoma
Interventions: BIOLOGICAL: ziv-aflibercept|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT