pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Polymethyl Methacrylate and (PEGT/PBT) Centralizer by the Uncemented BIHAPRO THP
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: DEVICE: PGET|DEVICE: PMMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hypertension Medications on Renal Blood Flow Measurements in Healthy Males (MK-0000-127)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Aliskiren|DRUG: Aliskiren|DRUG: Comparator: Losartan|DRUG: Comparator: Placebo to Aliskiren|DRUG: Comparator: Placebo to Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Vaccine (PolyPEPI1018 Vaccine) and TAS-102 for the Treatment of Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colon Adenocarcinoma|Metastatic Colorectal Adenocarcinoma|Metastatic Colorectal Carcinoma|Metastatic Microsatellite Stable Colon Carcinoma|Metastatic Microsatellite Stable Colorectal Carcinoma|Metastatic Rectal Adenocarcinoma|Microsatellite Stable Rectal Carcinoma|Stage IV Colorectal Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8
Interventions: BIOLOGICAL: Colorectal Cancer Peptide Vaccine PolyPEPI1018|DRUG: Trifluridine and Tipiracil Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous or Donor Stem Cell Transplantation in Treating Patients With Recurrent Non-Hodgkin's Lymphoma (BMT CTN 0202)
Status: TERMINATED
Conditions: Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Follicular Lymphoma
Interventions: DRUG: Cyclophosphamide and Rituximab|DRUG: Filgrastim|RADIATION: Chemotherapy or Radiation therapy|DRUG: Non-myeloablative Conditioning regimen|PROCEDURE: Allogeneic transplant|PROCEDURE: Autologous transplant|DRUG: Rituximab maintenance therapy|DRUG: GVHD Prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Multicenter, Phase 1b/2 Study of the Safety and Efficacy of KRT-232 Combined With Ruxolitinib in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera MF (Post-PV-MF), Or Post-Essential Thrombocythemia MF (Post ET-MF) Who Have a Suboptimal Response to Ruxolitinib
Status: RECRUITING
Conditions: Myelofibrosis
Interventions: DRUG: KRT-232|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial for Analysis of Intestinal Microbiome Affecting PK, PD, and Safety of Metformin
Status: COMPLETED
Conditions: Human Microbiome
Interventions: DRUG: Metformin (part 1)|DRUG: Vancomycin|DRUG: Metformin (part 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Efficacy, Safety and Tolerability of Targretin Capsules in Patients With Advanced or Metastatic Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: bexarotene with carboplatin and paclitaxel|DRUG: carboplatin and paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: US and MRI of the Forefoot: Intermetatarsal Bursitis or Morton's Neuroma
Status: RECRUITING
Conditions: Intermetatarsal Bursitis|Morton Neuroma|Intermetatarsal Neuroma
Interventions: DIAGNOSTIC_TEST: MRI with contrast|DIAGNOSTIC_TEST: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects on Glycemic Control of WBF-0031 in Subjects With Abnormal Glucose Tolerance
Status: UNKNOWN
Conditions: Abnormal Glucose Tolerance
Interventions: DIETARY_SUPPLEMENT: WBF-0031
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Clinical Study in Children With HeFH Aged 6 to 17 Treated Once Daily With Bempedoic Acid Oral Dosing
Status: RECRUITING
Conditions: Hypercholesterolemia
Interventions: DRUG: Bempedoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption for Treatment of Glioma
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DEVICE: Focused Ultrasound (FUS) BBB Disruption
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect iNO on Functional Respiratory Imaging in Subjects With WHO Group 3 Pulmonary Hypertension With COPD on Oxygen
Status: TERMINATED
Conditions: COPD|Pulmonary Hypertension|Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Inhaled Nitric Oxide 30mcg/kg IBW/hr
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pancreatic Cancer Early Detection Program
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer|Pancreas Cancer|Pancreatic Adenocarcinoma|Familial Pancreatic Cancer|BRCA 1/2|HNPCC|Lynch Syndrome|Hereditary Pancreatitis|FAMMM|Familial Atypical Multiple Mole Melanoma|Peutz Jeghers Syndrome
Interventions: PROCEDURE: Endoscopic Ultrasound|PROCEDURE: Magnetic Resonance Imaging (MRI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Application of Different Biomaterials in the Preservation of Vital Pulp in Carious Deciduous Teeth
Status: UNKNOWN
Conditions: Tooth, Deciduous
Interventions: PROCEDURE: indirect pulp capping|PROCEDURE: direct pulp capping|PROCEDURE: vital pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Reported Health-Related Quality of Life After Limited Access and Conventional Aortic Valve Replacement
Status: COMPLETED
Conditions: Aortic Valve Stenosis|Limited Access Aortic Valve Replacement|Quality of Life
Interventions: PROCEDURE: Limited access aortic valve replacement.|PROCEDURE: Conventional aortic valve replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Using a Personal Heart Rhythm Monitor to Diagnose Paroxsymal Atrial Fibrillation in the Community
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation|Stroke
Interventions: DEVICE: Automated Cardiac Event Recorder|DEVICE: Personal Heart Rhythm Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Personalised Assistive Devices Approach for Diabetic Foot Ulcer Prevention
Status: RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: Custom-made shoes: pressure-optimized|DEVICE: Custom-made indoor shoes: pressure optimized|DEVICE: Foot temperature monitoring|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Pharmacokinetics of Rilpivirine/Tenofovir/Emtricitabine After a Single-Oral Administration in Healthy Japanese Adult Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rilpivirine/Tenofovir Disoproxil Fumarate/Emtricitabine FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effect of Chinese Herbal Medicine on Food Allergy
Status: UNKNOWN
Conditions: Food Allergy
Interventions: DRUG: FAHF-2 (TM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: PEPI-TiDP23-C103: First-in-Human Study to Examine the Safety, Tolerability, and Plasma Pharmacokinetics of Increasing Single and Repeated Oral Doses of TMC558445 and of a Combined Single Day Dosing of Oral TMC558445 and Oral TMC310911 and Also Oral Darunavir
Status: COMPLETED
Conditions: HIV-1
Interventions: DRUG: TMC558445; TMC310911; Darunavir; Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials
Status: RECRUITING
Conditions: Myelodysplastic Syndromes (MDS)|Beta-thalassemia|Myeloproliferative Neoplasm(MPN)-Associated Myelofibrosis
Interventions: DRUG: Luspatercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Cobitolimod (Kappaproct®) in Chronic Active Treatment Refractory Ulcerative Colitis Patients
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: DRUG: Cobitolimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Involvement of Steatosis-induced Glucagon Resistance in Hyperglucagonaemia
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: PROCEDURE: Liver biopsy|OTHER: Pancreatic clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Antimicrobial Therapy as Adjunct to Periodontal Treatment: Effect of Timing
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: 3/d 500 mg metronidazole plus 375 mg amoxicillin for 7 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Closed Suction Drainage After Total Knee Replacement.
Status: UNKNOWN
Conditions: Total Knee Replacement
Interventions: PROCEDURE: Use of closed suction drainage following total knee arthroplasty|PROCEDURE: Abstain of using a closed suction drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Comparison of Radiation Exposure to Operators in Coronary Intervention Between Right Radial and Left DRA
Status: RECRUITING
Conditions: Radiation Exposure
Interventions: PROCEDURE: Radial Artery Puncture Method for Coronary Angiography and Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Radiofrequency Neurotomy for Chronic Facet Joint Related Neck Pain
Status: RECRUITING
Conditions: Neck Pain
Interventions: PROCEDURE: Radiofrequency neurotomy|PROCEDURE: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A National, Multicenter, Prospective, Observational Study to Assess Patient Characteristics, Treatment Algorithms and Disease Management of Hyperkalaemia Patients With Chronic Kidney Disease or Under Dialysis or With Heart Failure, Treated With Sodium Zirconium Cyclosilicate in Greece
Status: ACTIVE_NOT_RECRUITING
Conditions: Hyperkalaemia
Interventions: DRUG: sodium zirconium cyclosilicate (SZC)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multi-centre, Prospective, Observational Study on Effectiveness and Safety of ZOLADEX® (Goserelin Acetate Implant) 10.8 mg and ZOLADEX® (Goserelin Acetate Implant) 3.6 mg in Chinese Patients With Localized or Locally Advanced Hormonal Treatment -naïve Prostate Cancer
Status: COMPLETED
Conditions: Localized or Locally Advanced Prostate Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PSMA-PET: Deep Radiomic Biomarkers of Progression and Response Prediction in Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: 18F-DCFPyL IV injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Laser (Selective Retina Therapy) and Drug Combined Intervention in Clinically Significant Diabetic Macular Edema
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: COMBINATION_PRODUCT: R:GEN laser treatment (Selective Retina Therapy) and Lucentis (ranibizumab) combination therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Different Educational Strategies on the KAP, Psychological and Clinical Outcomes
Status: COMPLETED
Conditions: Ventilator-associated Pneumonia
Interventions: BEHAVIORAL: Routine Care|BEHAVIORAL: Routine care Plus the designed booklet|BEHAVIORAL: Routine care Plus the designed booklet Plus participation in oral presentations|BEHAVIORAL: Routine care Plus the designed booklet Plus participation in oral presentations Plus clinical teaching in bedside
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High Flow Nasal Oxygen Therapy in Pediatric Hypercapnic Respiratory Failure During Perioperative Stage
Status: UNKNOWN
Conditions: Respiratory Insufficiency
Interventions: DEVICE: High Flow Nasal Oxygen Therapy|DEVICE: Nasal CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Tolerance and Pharmacokinetics of TQB2858 Injection in Subjects With Terminal Malignant Tumors
Status: RECRUITING
Conditions: Terminal Malignant Tumors
Interventions: DRUG: TQB2858 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bivalent Vaccine With Escalating Doses of the Immunological Adjuvant OPT-821, in Combination With Oral β-glucan for High-Risk Neuroblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: adjuvant OPT-821 in a vaccine containing two antigens (GD2L and GD3L) covalently linked to KLH|BIOLOGICAL: oral β-glucan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OPtimized Stenting Using Intravascular Ultrasound(IVUS) in Long lEsion: Rationale for Simplified criteriA
Status: COMPLETED
Conditions: Coronary Heart Disease|Diabetes|Vascular Lesions|Chronic Total Occlusion of Coronary Artery|Restenosis
Interventions: DEVICE: TAXUS™ Element long stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Celecoxib, Fluorouracil, and Radiation Therapy in Treating Patients With Stage II or Stage III Rectal Cancer That Can Be Removed By Surgery
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: celecoxib|DRUG: fluorouracil|PROCEDURE: conventional surgery|RADIATION: radiation therapy|PROCEDURE: tumor biopsy|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Renal Function, Efficacy, and Safety When Switching From Tenofovir/Emtricitabine Plus a Protease Inhibitor/Ritonavir, to a Combination of Raltegravir (MK-0518) Plus Nevirapine Plus Lamivudine in HIV-1 Participants With Suppressed Viremia and Impaired Renal Function (MK-0518-284)
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: Raltegravir (MK-0518)|DRUG: Nevirapine|DRUG: Lamivudine|DRUG: Tenofovir|DRUG: Emtricitabine|DRUG: Lopinavir|DRUG: Ritonavir|DRUG: Atazanavir|DRUG: Darunavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Task-specific Epidural Stimulation Study
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Acute epidural stimulation for cardiovascular stability|DEVICE: Long Term Epidural Stimulation for Cardiovascular Stability|DEVICE: Participants undergo approximately 4 months of epidural stimulation for voluntary movement.|DEVICE: Long Term Epidural Stimulation for Cardiovascular Stability plus Stand Training|DEVICE: Participants undergo approximately 4 months of epidural stimulation for voluntary movement plus stand training.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Group Prenatal Care for Reducing the Risk of STDs in Pregnant Young Women
Status: COMPLETED
Conditions: Sexually Transmitted Diseases|HIV Infections
Interventions: BEHAVIORAL: CenteringPregnancy|BEHAVIORAL: CenteringPregnancyPlus|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Coronally Advanced Flap With Alloderm Versus Coronally Advanced Flap With Micro-needling on RT1 Gingival Recession
Status: UNKNOWN
Conditions: Gingival Recession|Recession, Gingival|Thin-gingiva
Interventions: PROCEDURE: Root coverage using coronally advanced flap combined with micro-needling|PROCEDURE: coronally advanced flap combined with Alloderm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Maximum Tolerated Dose of ASG-5ME in Subjects With Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Neoplasms
Interventions: DRUG: ASG-5ME
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Possible Beneficial Impact of Non-invasive and Invasive Neuromodulation on Freezing of Gait in Parkinson's Disease During Different Ambulatory Complexities: An Electrophysiological and fMRI Study
Status: RECRUITING
Conditions: Transcranial Direct Current Stimulation
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of High Dose Vitamin C on the Liver Function in Chronic Hepatitis Patients
Status: COMPLETED
Conditions: Chronic Hepatitis|Chronic Hepatitis C|Chronic Alcoholic Hepatitis
Interventions: DRUG: High dose vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Effects of Whey Compounds in Patients With Diabetes Mellitus Type 2.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: speWHE|DIETARY_SUPPLEMENT: WHE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deliver an Evidence-based Smoking Cessation Intervention for Smokers Attending A&E Departments in Hong Kong
Status: COMPLETED
Conditions: Smoking|Smoking Cessation|Evidence-Based Nursing|Emergency Service, Hospital
Interventions: BEHAVIORAL: an evidence-based smoking cessation intervention comprising brief advice plus active referrals
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Lateral Occlusion of Uterine Artery in Total Laparoscopic Hysterectomy
Status: UNKNOWN
Conditions: Postoperative Hemorrhage
Interventions: PROCEDURE: Lateral occlusion|PROCEDURE: Cervical occlusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In-line Filtration to Reduce Systemic Inflammatory Response Syndrome in Babies Born Very prEtErm
Status: COMPLETED
Conditions: Babies Born Very Preterm
Interventions: DEVICE: 0.2 micron positively charged PALL Corporation filters and 1.2 micro IV in-line filters used for lipid administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of DS-8201a, an Antibody Drug Conjugate for Advanced Breast Cancer Patients, With Biomarkers Analysis
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Tumors
Interventions: DRUG: DS-8201a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measure of Pharmacokinetic Parameters and Adherence With MEMS in Naive HIV Infected Patients Treated With Reyataz Once Daily Combined With Norvir and Truvada
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Atazanavir|DRUG: Ritonavir|DRUG: Tenofovir/emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of Eziclen®/Izinova® Versus Klean-prep® on Bowel Cleansing in Adolescents Undergoing Colonoscopy
Status: COMPLETED
Conditions: Digestive System Disease
Interventions: DRUG: Eziclen®/Izinova®|DRUG: Klean-Prep®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Management of Acute Pulmonary Hypertensive Crisis in Children With Known Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Phenylephrine|DRUG: Epinephrine|DRUG: Arginine Vasopressin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CRT-P or CRT-D in Dilated Cardiomyopathy
Status: NOT_YET_RECRUITING
Conditions: Cardiomyopathy, Dilated, 3B
Interventions: DEVICE: CRT-D|DEVICE: CRT-P
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety, Pharmacodynamics, Pharmacokinetics, and Exploratory Efficacy of GZ/SAR402671 in Treatment-naïve Adult Male Patients With Fabry Disease
Status: COMPLETED
Conditions: Fabry Disease
Interventions: DRUG: GZ/SAR402671
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib and Pembrolizumab in People With Advanced Adenoid Cystic Carcinoma and Other Salivary Gland Cancers
Status: RECRUITING
Conditions: Adenoid Cystic Carcinoma|Salivary Gland Cancer
Interventions: DRUG: Lenvatinib|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Organ Preservation Strategies After Chemoradiotherapy Combined With Immunotherapy for Esophageal Cancer (PALACE3).
Status: RECRUITING
Conditions: Esophageal Cancer
Interventions: COMBINATION_PRODUCT: Experimental: Arm 1 Organ preservation|COMBINATION_PRODUCT: Active Comparator: Arm 2 Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction - DOSE Finding Study
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: Olpasiran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Multiscore Feedback in Professionalism for Anesthesia
Status: COMPLETED
Conditions: CA2 and CA3 Residents Doing a Two Month Rotation in|Pediatric Anesthesia Department
Interventions: OTHER: Feedback group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Clinical Research of the Safety and Effectiveness Evaluation for Using Echocardiography-guided Liwen RF Radiofrequency Ablation System to Treat Hypertrophic Obstructive Cardiomyopathy
Status: UNKNOWN
Conditions: Hypertrophic Obstructive Cardiomyopathy
Interventions: PROCEDURE: Echocardiography-guided Radiofrequency ablation for Hypertrophic obstructive Cardiomyopathy (HOCM).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Siltuximab In Siltuximab-RElapsed/REfractory Multicentric CAstleman Disease
Status: TERMINATED
Conditions: Idiopathic Multicentric Castleman's Disease
Interventions: DRUG: Siltuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Brain Stimulation for Treating Symptomatic Convergence Insufficiency
Status: RECRUITING
Conditions: Convergence Insufficiency
Interventions: DEVICE: Anodal-Transcranial Direct Current Stimulation|BEHAVIORAL: Office-Based Vergence/Accommodative Therapy|DEVICE: Sham Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PhotoDynamic Therapy for Line Infection Prevention (PLIP): Pilot Study on Healthy Volunteers.
Status: COMPLETED
Conditions: Light; Therapy, Complications
Interventions: PROCEDURE: Methylene blue and light treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Droperidol Versus Metoclopramide + Diphenhydramine for the Treatment of Primary Headaches
Status: TERMINATED
Conditions: Primary Headaches (Includes Migraines, Tension, Cluster Headaches)
Interventions: DRUG: Droperidol|DRUG: Metoclopramide + diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microbiological Impact of an Intimate Cream and Its Suitability to Contribute to the Feeling of Softness and Freshness in the Intimate Area of Women
Status: COMPLETED
Conditions: Post Menopausal Dryness in the Intimate Area of Women
Interventions: DEVICE: probiotic creme|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alcohol Use Disorders- Mobile Based Brief Intervention Treatment (AMBIT): A Pilot RCT
Status: COMPLETED
Conditions: Hazardous Drinking
Interventions: BEHAVIORAL: AMBIT (Alcohol use disorders- mobile based Brief Intervention treatment) intervention|BEHAVIORAL: Face to face Brief Intervention|BEHAVIORAL: BI leaflet intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Electrical Stimulation in Chronic Ankle Instability
Status: UNKNOWN
Conditions: Joint Instability|Ankle Sprains|Sport Injury
Interventions: DEVICE: Functional electrical stimulation device (NESS L300Plus, Bioness, Valencia, CA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Cabozantinib in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Urothelial Carcinoma|Renal Cell Carcinoma|Non-Small Cell Lung Cancer|Castration-resistant Prostate Cancer|Triple Negative Breast Cancer|Ovarian Cancer|Endometrial Cancer|Hepatocellular Carcinoma|Gastric Cancer|Gastroesophageal Junction Adenocarcinoma|Colorectal Cancer|Head and Neck Cancer|Differentiated Thyroid Cancer|Lower Esophageal Cancer
Interventions: DRUG: cabozantinib|DRUG: atezolizumab|DRUG: cabozantinib|DRUG: cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acute Fructose Load in Human
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Diabetes Mellitus, Type 2
Interventions: OTHER: Blueberry drink|OTHER: Blueberry and pizza|OTHER: Soft beverage|OTHER: Soft beverage and pizza|OTHER: Fructose|OTHER: Fructose and pizza
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of Activated Marrow Infiltrating Lymphocytes Alone or in Conjunction With an Allogeneic Granulocyte Macrophage Colony-stimulating Factor (GM-CSF)-Based Myeloma Cellular Vaccine in the Autologous Transplant Setting in Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: Activated marrow infiltrating lymphocytes|BIOLOGICAL: Allogeneic Myeloma Vaccine|DRUG: Cyclophosphamide|BIOLOGICAL: Filgrastim|PROCEDURE: Leukapheresis|DRUG: Melphalan|BIOLOGICAL: Autologous stem cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial in Healthy Men and Women to Find Out How Well Different Doses of BI 1291583 Are Tolerated
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1291583|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Association Between Variation in Oxygen Saturation (ScO2) and Incidence of Postoperative Cognitive Dysfunction (POCD) in a Population of Elderly Patients Admitted for Emergency Surgery.
Status: UNKNOWN
Conditions: Cerebral Saturation|Cognitive Impairment|Emergencies
Interventions: OTHER: To evaluate the relationship between oxygen saturation and the incidence of postoperative cognitive dysfunction in emergency surgery in elderly patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of SCM-AGH in Subjects With Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: BIOLOGICAL: SCM-AGH|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAP7.1 for the Treatment of Advanced Stage, Therapy Refractory Lung and Biliary Tract Tumors
Status: TERMINATED
Conditions: Advanced Endstage Solid Carcinomas in Adults
Interventions: DRUG: CAP7.1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ventilatory Adaptation to Concentric Versus Eccentric Exercise in Patients With Severe COPD
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease Severe
Interventions: OTHER: Incremental Concentric-eccentric exercise test|OTHER: Incremental Eccentric-concentric exercise test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Tinnitus Using Eutectic Mixture of Local Anesthetics (EMLA) 5% Cream
Status: COMPLETED
Conditions: Tinnitus
Interventions: DRUG: EMLA cream 5%|OTHER: cetomacrogol cream (lotion cream)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study of Apixaban With Cyclosporine or Tacrolimus in Transplant Recipients
Status: COMPLETED
Conditions: Pharmacokinetics|Kidney Transplant|Lung Transplant
Interventions: DRUG: Apixaban
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Low-Dose Sirolimus to Increase Hematopoietic Function in Patients With RUNX1 Familial Platelet Disorder
Status: RECRUITING
Conditions: Familial Platelet Disorder|Hematopoietic
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stabilometric and Baropodometric Evaluation After Osteopathic Scaphoid Tug Manipulation
Status: COMPLETED
Conditions: Manipulation|Osteopathic
Interventions: PROCEDURE: Experimental: Osteopathic manipulation TUG for scaphoid bone|PROCEDURE: Sham group: Sham osteopathic manipulation TUG for scaphoid bone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Imaging the Effects of rTMS on Chronic Pain
Status: SUSPENDED
Conditions: Chronic Pain|Opioid-use Disorder
Interventions: DEVICE: Active rTMS treatment|DEVICE: Sham rTMS treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: What Are the Brakes and Levers of Physical Activity Practice for Patients With Chronic Lower Back Pain?
Status: COMPLETED
Conditions: Non-specific Chronic Lower Back Pain
Interventions: BEHAVIORAL: Back Belief questionnaire|BEHAVIORAL: QUEBEC scale|BEHAVIORAL: Fear Avoidance beliefs questionnaire|BEHAVIORAL: Visual analog scale|BEHAVIORAL: individual interviews|BEHAVIORAL: Focus groups
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Manual Therapy Versus Manual Therapy and Exercise and Education in Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pains|Posterior Cervical Pains|Posterior Neck Pain|Cervicalgia
Interventions: OTHER: Manual Therapy and Education|OTHER: Manual Therapy|OTHER: Manual therapy, Education and Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Spectra Optia CMNC Collection Procedure
Status: COMPLETED
Conditions: Healthy Apheresis Donors|Mononuclear (MNC) Cell Donors
Interventions: DEVICE: Spectra Optia CMNC|DEVICE: COBE Spectra MNC|DRUG: Granulocyte-colony stimulating factor (G-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Combination Chemotherapy Treatments in Patients With Colorectal Cancer Stage II and III
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: Capecitabine and Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral dIuretics in Very Intensive Treatment, an Early Intervention in Outpatients With Heart Failure
Status: UNKNOWN
Conditions: Heart Failure|Congestive Heart Failure
Interventions: DRUG: Bumetanide 1 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial on the Efficacy of Gastric Probiotics in the Treatment of Helicobacter Pylori Infection
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: OTHER: Lactobacillus plantarum|OTHER: Bacillus coagulans|OTHER: Lactobacillus plantarum + Bacillus coagulans|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Nisoldipine Extended-Release Tablets, 30 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nisoldipine Extended-release Tablets, 30 mg|DRUG: Sular® Extended Release Tablets, 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Randomized, Placebo-Controlled Study of AbobotulinumtoxinA (Dysport®) for the Treatment of Cervical Dystonia
Status: COMPLETED
Conditions: Cervical Dystonia
Interventions: BIOLOGICAL: Botulinum toxin type A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Extended Low Dose Prednisolone in Achieving Clinical and Biochemical Remission in Steroid Responsive Severe Alcoholic Hepatitis
Status: NOT_YET_RECRUITING
Conditions: Severe Alcoholic Hepatitis
Interventions: DRUG: Prednisolone|OTHER: Standard Medical therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validity and Inter-Rater Reliability of a Novel Bedside Referral Tool for Spasticity
Status: COMPLETED
Conditions: Spasticity, Muscle|Muscular Diseases|Musculoskeletal Disease|Muscle Hypertonia|Muscle Spasticity|Neuromuscular Manifestations|Signs and Symptoms|Nervous System Diseases|Neurologic Manifestations
Interventions: DIAGNOSTIC_TEST: Bedside Referral Tool|OTHER: Neurological Examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Instant and Lasting Relief Effects of Strontium Chloride/Potassium Nitrate Dentifrice on Dentin Hypersensitivity
Status: COMPLETED
Conditions: Dentine Hypersensitivity
Interventions: OTHER: control dentifrice|OTHER: strontium chloride/potassium nitrate dentifrice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Methodological and Technical DEvelopmeNts to Improve the Quality and Comfort of Magnetic Resonance Imaging Exam on Voluntary Subjects
Status: RECRUITING
Conditions: Healthy|Pathology
Interventions: DEVICE: MRI examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Auditory Temporal Processes in Aging
Status: COMPLETED
Conditions: Auditory Perceptual Disorders|Aging Problems
Interventions: BEHAVIORAL: Auditory training with feedback|BEHAVIORAL: Listening paradigm with no feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Online Mindfulness Program for Stress Management
Status: COMPLETED
Conditions: Stress, Psychological|Burnout, Professional
Interventions: BEHAVIORAL: Internet-Based Mindfulness Program - Stress Free Now for Healers|BEHAVIORAL: Active Control Group - Relaxing Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparative Study of BAT2206 With Stelara® in Patients With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: BAT2206|DRUG: Stelara (EU-sourced)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Doripenem in the Treatment of Complicated Intra-Abdominal Infections
Status: COMPLETED
Conditions: Bacterial Infections and Mycoses|Appendicitis|Cholecystitis|Pancreatitis|Peritonitis
Interventions: DRUG: doripenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Ferric Citrate for the Treatment of Hyperphosphatemia in Patients With Chronic Kidney Disease Undergoing Hemodialysis
Status: COMPLETED
Conditions: Hyperphosphatemia|End Stage Renal Disease|ESRD
Interventions: DRUG: Ferric Citrate|DRUG: Sevelamer Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Quantitative Light Induced Fluorescence Digital as an Oral Hygiene Evaluation Tool in Orthodontics
Status: COMPLETED
Conditions: Complication of Personal Oral Hygiene
Interventions: OTHER: QLF Image|OTHER: White Light Image
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Contribution of Hypnotic Analgesia to Local Anesthesia During Bronchial Endoscopy.
Status: TERMINATED
Conditions: Patient With Bronchial Endoscopy
Interventions: OTHER: hypnotic analgesia|OTHER: music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: How Much Vitamin D is Needed in Milk Products to Support Vitamin D Intake and Bone Health in Children?
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Vitamin D fortified yogurt and cheese products|OTHER: Control Group 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Safety and Efficacy Study of GC1008 to Treat Renal Cell Carcinoma or Malignant Melanoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell|Melanoma
Interventions: BIOLOGICAL: GC1008 Human Anti Transforming Growth Factor _Beta (TGFβ) Monoclonal Antibody|BIOLOGICAL: GC1008 Human Anti Transforming Growth Factor _Beta (TGFβ) Monoclonal Antibody|BIOLOGICAL: GC1008 Human Anti Transforming Growth Factor _Beta (TGFβ) Monoclonal Antibody|BIOLOGICAL: GC1008 Human Anti Transforming Growth Factor _Beta (TGFβ) Monoclonal Antibody|BIOLOGICAL: GC1008 Human Anti Transforming Growth Factor _Beta (TGFβ) Monoclonal Antibody|BIOLOGICAL: GC1008 Human Anti Transforming Growth Factor _Beta (TGFβ) Monoclonal Antibody|BIOLOGICAL: GC1008 Human Anti Transforming Growth Factor _Beta (TGFβ ) Monoclonal Antibody|BIOLOGICAL: GC1008 Human Anti Transforming Growth Factor _Beta (TGFβ) Monoclonal Antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance Therapy of Hypomethylating Agent (HMA) in Favorable Risk Acute Myeloid Leukemia (AML) Patients
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Hypomethylating agent, Azacitidine or Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Intermittent Fasting Induce Weight Loss and Improve Gut Health as Compared to Standard Medical Care in Patients With Obesity/High BMI and Crohn's Disease.
Status: NOT_YET_RECRUITING
Conditions: Crohn Disease
Interventions: OTHER: Intermittent Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Incentivizing Behavior Change Skills to Promote Weight Loss
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: incentives for dietary self-monitoring|BEHAVIORAL: incentives for interim weight loss|BEHAVIORAL: incentives for both
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I-II Study Investigating the All Oral Combination of the Menin Inhibitor SNDX-5613 With Decitabine/Cedazuridine (ASTX727) and Venetoclax in Acute Myeloid Leukemia (SAVE)
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: SNDX-5613|DRUG: Venetoclax|DRUG: ASTX727
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Impact of KT Along With BT in Patients With Chronic Low Back Pain of Sacroiliac Joint Dysfunction
Status: COMPLETED
Conditions: Sacroiliac Joint Dysfunction
Interventions: OTHER: Kinesio Taping|OTHER: Balance Training (BT)|OTHER: Hot Pack and Stretching Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ultrasound Hyperthermia Combined With Chemotherapy on Oral and Maxillofacial-Head and Neck Cancer
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: DEVICE: Ultrasound Hyperthermia|DRUG: Docetaxel,Cisplatin,Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Long Term Efficacy and Durability of the BrainsWay Deep TMS in OCD Subjects
Status: UNKNOWN
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: BrainsWay Deep TMS HAC/H7-Coil|DEVICE: BrainsWay Deep TMS Sham Coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Gliosarcoma|MGMT-Unmethylated Glioblastoma
Interventions: PROCEDURE: Contrast-enhanced Magnetic Resonance Imaging|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab|DEVICE: NovoTTF-100A Device|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Radiation Therapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Safety, Pharmacokinetics and Pharmacodynamics of MEDI6012 in Subjects With Stable Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: BIOLOGICAL: MEDI6012|BIOLOGICAL: Placebo SC|BIOLOGICAL: Placebo IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT