pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of Different Formulations of an A/H1N1 Pandemic Vaccine in Healthy Children Aged 6 Months to 9 Years
Status: COMPLETED
Conditions: Influenza|Swine-origin A/H1N1 Influenza
Interventions: BIOLOGICAL: Monovalent Subvirion A/H1N1 Influenza vaccine|BIOLOGICAL: Monovalent Subvirion A/H1N1 Influenza vaccine|BIOLOGICAL: Normal saline solution (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Benralizumab (KHK4563) in Patients With Eosinophilic Chronic Rhinosinusitis
Status: COMPLETED
Conditions: Eosinophilic Chronic Rhinosinusitis
Interventions: DRUG: benralizumab|DRUG: benralizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Placebo-controlled Study in Patients With Parkinson's Disease to Evaluate the Effect of Rotigotine on Non-motor Symptoms
Status: COMPLETED
Conditions: Idiopathic Parkinson's Disease
Interventions: OTHER: Placebo|DRUG: Rotigotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ofatumumab Versus Rituximab in Children With Steroid and Calcineurin Inhibitor Dependent Idiopathic Nephrotic Syndrome
Status: COMPLETED
Conditions: Nephrotic Syndrome
Interventions: DRUG: Ofatumumab|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Conditioning for Cerebral Ischemia in Patients With Takayasu Arteritis (TARIC-1)
Status: NOT_YET_RECRUITING
Conditions: Cerebral Ischemia|Takayasu Arteritis
Interventions: DEVICE: RIC|DEVICE: sham-RIC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Validation of a Smartphone-based Intelligent Diagnosis and Measurement for Strabismus
Status: RECRUITING
Conditions: Strabismus|Exotropia|Esotropia|Vertical Strabismus
Interventions: DIAGNOSTIC_TEST: A new technology based on 3D reconstruction and deep learning algorithm to achieve an automatic diagnosis of strabismus based on patient-sourced videos of programmatic cover tests.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Perceptions of Burden in Patients With Late-Stage Cancer and Their Caregivers
Status: WITHDRAWN
Conditions: Brain and Central Nervous System Tumors|Chronic Myeloproliferative Disorders|Depression|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Psychosocial Effects of Cancer and Its Treatment|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: OTHER: medical chart review|OTHER: questionnaire administration|PROCEDURE: psychosocial assessment and care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Imaging Study to Compare Effects of Darolutamide and Enzalutamide With Respect to Placebo on the Blood Flow in the Brain in Healthy Male Volunteers.
Status: COMPLETED
Conditions: Cerebrovascular Circulation
Interventions: DRUG: Darolutamide (BAY1841788)|DRUG: Enzalutamide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment to Promote Self-regulation in Children With Autism Spectrum Disorder
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Self-Regulation, Emotion
Interventions: DEVICE: repetitive transcranial magnetic stimulation (rTMS)|OTHER: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VELCADE/Melphalan/Prednisone Versus Melphalan/Prednisone in Patients With Previously Untreated Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-arterial Lutetium-177-dotatate for Treatment of Patients With Neuro-endocrine Tumor Liver Metastases
Status: COMPLETED
Conditions: Neuroendocrine Tumors|Liver Metastases
Interventions: DRUG: Lutetium Lu 177-DOTATATE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self Transcranial Direct Current Stimulation for Pain in Older Adults With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis|Chronic Pain
Interventions: DEVICE: Soterix 1x1 tDCS mini-CT Stimulator device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibuprofen or Morphine in Treating Pain in Patients Undergoing Pleurodesis for Malignant Pleural Effusion
Status: UNKNOWN
Conditions: Metastatic Cancer
Interventions: DRUG: ibuprofen|DRUG: morphine sulfate|PROCEDURE: management of therapy complications|PROCEDURE: pleurodesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Homologous vs Heterologous Third Vaccination in Kidney Transplant Recipients Kidney Transplant Recipients
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Ad26COVS1|DRUG: ChAdOx1 SARS2 Vaccine|DRUG: BNT162B2|DRUG: mRNA-1273
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lubiprostone Effect on Gastrointestinal Tract Transit Times Measured by Smartpill in Patients With Chronic Constipation
Status: COMPLETED
Conditions: Chronic Idiopathic Constipation
Interventions: DRUG: Lubiprostone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PART B: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and Without mGluR Mutations
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: AEVI-001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acceleration of Orthodontic Tooth Movement
Status: COMPLETED
Conditions: Mild to Moderate Anterior Mandibular Segment Crowdind
Interventions: DRUG: Dihydroxycholecalciferols|OTHER: dimethyl sulfoxide|OTHER: serum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential Immunochemotherapy Treatment With Pembrolizumab Plus Dendritic Cell (DC) Vaccine Followed by Trifluridine/Tipiracil Plus Bevacizumab in Refractory Mismatch-repair-proficient (pMMR) or Microsatellite-stable (MSS) Metastatic Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer Metastatic|Microsatellite Stable Colorectal Carcinoma|Refractory Mismatch-repair-proficient (pMMR) Metastatic Colorectal Cancer
Interventions: BIOLOGICAL: Autologous Dendritic Cell (DC) Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Letrozole Step-up Protocol for Ovulation Induction in Infertile Women With PCOS
Status: COMPLETED
Conditions: Infertility Poly Cystic Ovary
Interventions: DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This Study Observes the Usage of Non-vitamin K Antagonist Oral Anticoagulants (NOACs) in Elderly Patients With a Heart Rhythm Disorder in Spain
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Non-vitamin K antagonist oral anticoagulant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Application of Fibrin Glue (Tissucol Duo Quick) in External Eye Surgeries
Status: COMPLETED
Conditions: Corneal Ulcers|Cataract|Pterygium|Retinal Detachment
Interventions: PROCEDURE: Fibrin Glue assisted external eye surgery|DEVICE: Fibrin glue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of SKB264 for EGFR Mutant NSCLC Patients
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: SKB264|DRUG: Pemetrexed|DRUG: Carboplatin|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Chit-Chat Educational Intervention to Promote Advance Care Planning in the Community
Status: ACTIVE_NOT_RECRUITING
Conditions: Old Age|Family Members
Interventions: OTHER: Chit-Chat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: FUS Etoposide for DMG
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Intrinsic Pontine Glioma|Diffuse Midline Glioma, H3 K27M-Mutant
Interventions: DRUG: Etoposide; Oral, 50 Mg|DEVICE: Focused ultrasound with neuro-navigator-controlled sonication
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory CSII Trial on Erectile Dysfunction in T2DM Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Erectile Dysfunction
Interventions: DRUG: Insulin|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RT-310 Dose Escalation BPH Study
Status: RECRUITING
Conditions: BPH (Benign Prostatic Hyperplasia)|Lower Urinary Tract Symptoms
Interventions: COMBINATION_PRODUCT: RT-310
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Compare the Pharmacokinetics of Imatinib Mesylate Tablet 400mg (1 Tablet) and Glivec Film-coated Tablet 100mg (4 Tablets)(Phase I)
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia|Gastrointestinal Stromal Tumor
Interventions: DRUG: Imatinib mesylate tablet 400 mg, 1 Tablet|DRUG: Glivec film-coated tablet 100 mg, 4 Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olanzapine for the Prevention of Chemotherapy-Induced Nausea and Vomiting in Chinese Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Experimental drug: Aprepitant|DRUG: Experimental drug: Ondansetron|DRUG: Experimental drug: Dexamethasone|DRUG: Experimental drug: Olanzapine|DRUG: Standard: Aprepitant|DRUG: Standard: Ondansetron|DRUG: Standard: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplementation of 500mg Trans-resveratrol Within Hypoxic and Normoxic Conditions, in Healthy Humans.
Status: COMPLETED
Conditions: Hypoxia, Brain
Interventions: DIETARY_SUPPLEMENT: Resveratrol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Evaluation of the McGrath Videolaryngoscope and the Direct Laryngoscopy for Tracheal Intubation in the Prehospital Setting
Status: UNKNOWN
Conditions: Indication of Orotracheal Intubation|Cardio Respiratory Arrest|Respiratory Failure|Neurological Failure
Interventions: DEVICE: Videolaryngoscopy group|DEVICE: Direct laryngoscopy group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of DTRAX Graft in Patients With Cervical Degenerative Disc Disease
Status: WITHDRAWN
Conditions: Cervical Spondylosis|Cervical Radiculopathy|Cervical Degenerative Disc Disease
Interventions: DEVICE: DTRAX Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Book Sharing for Toddlers With Clefts
Status: ENROLLING_BY_INVITATION
Conditions: Cleft Palate|Cleft Lip and Palate
Interventions: BEHAVIORAL: Book-Sharing for Toddlers with Clefts (BOOST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Pulse Stimulation of the Brain
Status: RECRUITING
Conditions: Mild Dementia|Aging Well
Interventions: DEVICE: Neurolith Transcranial Pulse Stimulation Active|DEVICE: Neurolith Transcranial Pulse Stimulation Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Pemetrexed + Platinum Chemotherapy + Pembrolizumab (MK-3475) With or Without Lenvatinib (MK-7902/E7080) as First-line Intervention in Adults With Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-7902-006/E7080-G000-315/LEAP-006)
Status: ACTIVE_NOT_RECRUITING
Conditions: Nonsquamous Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Pemetrexed|DRUG: Lenvatinib|DRUG: Placebo matching lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Homoharringtonine (Omacetaxine Mepesuccinate) in Treating Patients With Chronic Myeloid Leukemia (CML) With the T315I BCR-ABL Gene Mutation
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Omacetaxine mepesuccinate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of Laropiprant on the Antiplatelet Effects of Clopidogrel and Aspirin in Combination (MK-0524A-114)(COMPLETED)
Status: COMPLETED
Conditions: Primary Hypercholesterolemia|Mixed Hyperlipidemia
Interventions: DRUG: niacin (+) laropiprant|DRUG: Comparator: aspirin|DRUG: Comparator: clopidogrel|DRUG: Comparator: laropiprant|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The CYBERnetic Lower Limb Cocognitive Ortho-prosthesis Plus Plus, 1st Clinical Study (CLs++)
Status: UNKNOWN
Conditions: Lower Limb Amputation Above Knee (Injury)
Interventions: DEVICE: CLs++ gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Amphotericin B Lipid Complex in the Treatment of Cryptococcal Meningitis in Patients With the Acquired Immunodeficiency Syndrome
Status: COMPLETED
Conditions: Meningitis, Cryptococcal|HIV Infections
Interventions: DRUG: Amphotericin B, Lipid-based|DRUG: Amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of the Quantity of Distal Movement of the Upper Canine and Molar
Status: COMPLETED
Conditions: Malocclusion
Interventions: DEVICE: Class II elastics and Sliding Jig|DEVICE: Class II elastic alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scintigraphy Study to Assess Gastric Emptying in Healthy Subjects Given GSK716155 or Placebo.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: GSK716155|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sildenafil After the Fontan Operation
Status: COMPLETED
Conditions: Hypoplastic Left Heart Syndrome|Tricuspid Atresia
Interventions: DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) Against COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: BIOLOGICAL: Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Once-Daily Dosing of FoamOtic Cipro Compared to Twice-Daily Dosing of Ciloxan Ear Drops in Patients With Acute External Otitis
Status: COMPLETED
Conditions: Otitis Externa|Otorhinolaryngologic Diseases|Ear Diseases|Otitis
Interventions: DRUG: 0.3% Ciprofloxacin Ear Drops|DRUG: FoamOtic Cipro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Assisted Treatment of Chronic Sinusitis With and Without Light Activated Agents
Status: UNKNOWN
Conditions: Rhinosinusitis
Interventions: DEVICE: Laser + ICG|DEVICE: Laser only
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: LME636 in the Relief of Persistent Ocular Discomfort in Subjects With Severe Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye
Interventions: BIOLOGICAL: LME636 ophthalmic solution|BIOLOGICAL: LME636 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharyngitis,Group A Streptococcal Infection,Rapid Streptococcal Test,Throat Swab Culture
Status: COMPLETED
Conditions: Pharyngitis
Interventions: PROCEDURE: Rapid Immunochromatographic streptococcal test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Use of Laser in the Treatment of Atrophic Vulvovaginitis
Status: TERMINATED
Conditions: Lasers|Atrophy of Vagina|Atrophy Vulva
Interventions: PROCEDURE: Laser diiodo|PROCEDURE: Laser Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TPF Induction With Concomitant Chemoradiation to Treat Patients With Head and Neck Cancer
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: RADIATION: conventional radiotherapy with 'high' dose cisplatin|RADIATION: accelerated radiotherapy with 'low' dose cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous N-Acetylcysteine for the Treatment of Acute Ischemic Stroke
Status: UNKNOWN
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Acetylcysteine|DRUG: Dextrose in Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Youth Outlook on Life Opportunities Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Childbearing, Delayed|Marriage Age|Educational Problems|Anxiety|Age Related Female Infertility
Interventions: OTHER: Information about age-related fertility|OTHER: Information about policy initiatives|OTHER: Information about diabetes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Conservative Therapy of Proximal Phalanx Fractures - Comparing the Lucerne Cast With Finger Splinting
Status: NOT_YET_RECRUITING
Conditions: Proximal Phalanx Fracture
Interventions: PROCEDURE: Lucerne Cast|PROCEDURE: Forearm Cast and Finger Splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Cognitive Decline in Older Adults With Low Dha/Epa Index in Red Blood Cells
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Omega-3 treatment|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Cranberry Supplementation on Chronic Kidney Disease Patients.
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic|Inflammation|Oxidative Stress|Gastrointestinal Microbiome
Interventions: DIETARY_SUPPLEMENT: Cranberry|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Observational Study of Glucose Tolerance Abnormalities in Patient With Cystic Fibrosis Homozygous for Phe 508 Del CFTR Treated by Lumacaftor-Ivacaftor
Status: COMPLETED
Conditions: Cystic Fibrosis Homozygous for Phe 508 Del CFTR|Glucose Intolerance or Newly Diagnosis Diabetes
Interventions: DRUG: Lumacaftor-Ivacaftor treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antioxidants for Prevention of Cataracts Follow-up Study
Status: COMPLETED
Conditions: Cataract
Interventions: DIETARY_SUPPLEMENT: Antioxidant|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Safety, Tolerability and Pharmacokinetics of Testosterone Undecanoate in Hypogonadal Males.
Status: COMPLETED
Conditions: Hypogonadal Males
Interventions: DRUG: ABT-SLV361|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Context - Remote Ischemic Conditioning in Renal Transplantation - Effect on Immediate and Extended Kidney Graft Function
Status: UNKNOWN
Conditions: Kidney Transplantation|Delayed Graft Function|Acute Kidney Injury|Glomerular Filtration Rate
Interventions: OTHER: Remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Ciclesonide and Fluticasone Propionate in Adult Patients With Moderate and Severe Persistent Asthma (18 to 75 y) (BY9010/IT-101)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Ciclesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Lancing Devices Regarding Capillary Blood Volume and Lancing Pain Intensity.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DEVICE: Lancing device A|DEVICE: Lancing device B|DEVICE: Lancing device C|DEVICE: 28 G lancet|DEVICE: 30 G lancet|DEVICE: 33 G lancet|OTHER: Lancing depth setting (1)|OTHER: Lancing depth setting (5)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Imiquimod 3.75% Cream in Combination With Cryotherapy in the Treatment of Hypertrophic Actinic Keratoses
Status: UNKNOWN
Conditions: Actinic Keratosis
Interventions: DRUG: Cryotherapy alone to Left arm plus cryotherapy + imiquimod to Right arm|DRUG: Cryotherapy alone to Left arm plus cryotherapy + imiquimod to Right arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: OCT Evaluation of Early Vascular Repair in Patients With Non ST Elevation Acute Coronary Syndrome (NSTE-ACS)
Status: UNKNOWN
Conditions: Unstable Anginas|Non ST Segment Elevation Myocardial Infarction
Interventions: DEVICE: OCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concentrated Growth Factors in Treatment of Intrabony Defects in Localized Aggressive Periodontitis
Status: COMPLETED
Conditions: Aggressive Periodontitis
Interventions: PROCEDURE: GTR|PROCEDURE: concentrated growth factor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Respiratory Kinematics of Cough in Healthy Older Adults and Parkinson's Disease
Status: COMPLETED
Conditions: Cough|Parkinson's Disease
Interventions: DRUG: Capsaicin|OTHER: Voluntary cough test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Alveolar Soft Part Sarcoma|Leiomyosarcoma|Synovial Sarcoma|Soft-Tissue Sarcoma
Interventions: DRUG: AL3818|DRUG: Dacarbazine|DRUG: AL3818 or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SpyGlass AMEA Registry
Status: COMPLETED
Conditions: Biliary Stricture|Biliary Obstruction Due to Common Bile Duct Stone|Periampullary Tumor|Hemobilia
Interventions: PROCEDURE: ERCP (Endoscopic Retrograde Cholangiopancreatography)|DEVICE: SpyGlass DVS and SpyGlass Digital Simple (DS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Local Non-salvage Radiotherapy for Synchronous Oligometastatic Non-small-cell Lung Cancer.
Status: UNKNOWN
Conditions: Stage IV Non-small Cell Lung Cancer
Interventions: RADIATION: Local Definitive Radiotherapy|DRUG: No Local Definitive Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing the Safety of Two Different Intravenous Iron Formulations
Status: SUSPENDED
Conditions: Iron Deficiency Anemia|Perioperative Blood Conservation
Interventions: DRUG: Iron dextran|DRUG: Iron sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid and Ethamsylate For Preventing PPH in Patient Undergoing LSCS at High Risk For PPH
Status: UNKNOWN
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Tranexamic Acid and Ethamsylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Health Benefits of Expressive Writing Among Chinese Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Cancer|Breast Neoplasms
Interventions: BEHAVIORAL: Self-Regulation Condition|BEHAVIORAL: Enhanced self-Regulation Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Identification of Risk Factors for the Occurrence of High-grade Rhythm Disorders in Patients With ST-segment Elevation Myocardial Infarction (STEMI)
Status: COMPLETED
Conditions: Arrythmia -Myocardial Infarction
Interventions: OTHER: collection of medical and socio-demographic data
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neurobiological Effects of Oxytocin in Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Cellular Immunotherapy Synergize Chemotherapy in Patients With Stage IV NSCLC
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: BIOLOGICAL: chemotherapy followed dendritic cells|DRUG: pemetrexed and carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Micro Glucagon During Exercise in Type 1 Diabetes
Status: WITHDRAWN
Conditions: Type 1 Diabetes|Hypoglycemia
Interventions: DRUG: Micro-glucagon|DRUG: Mini-glucagon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Indacaterol Acetate Delivered Via the Concept1 Inhalation Device in Children Greater or Equal to 6 and Less Than 12 Years of Age With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Indacaterol acetate 75 μg|DRUG: Indacaterol acetate 150 μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transplantation of Fibroblast for Correction of Nasolabial Folds
Status: UNKNOWN
Conditions: Nasolabial Folds|Skin Aging
Interventions: BIOLOGICAL: Fibroblast|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utilization of Rehabilitation Prior to Surgery Among Patients With Anterior-cruciate Ligament Knee Injury
Status: NOT_YET_RECRUITING
Conditions: Anterior-cruciate Ligament Knee Injury
Interventions: BEHAVIORAL: Rehabilitation before knee surgery (prehab)|BEHAVIORAL: Post-surgery rehabilitation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Sevoflurane and Ketamine on QT in Electroconvulsive Therapy
Status: COMPLETED
Conditions: Major Depression|Electroconvulsive Therapy
Interventions: DRUG: Sevoflurane|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Budesonide Diluted to Maximum Clinical Treatment of Patients With Chronic Rhinosinusitis With Polyoposis.
Status: RECRUITING
Conditions: Chronic Rhinosinusitis (Diagnosis)
Interventions: DRUG: Budesonide Nasal|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MRI-based 3D Hip Labrum and Cartilage Morphology in Patients With Hip Deformities Compared to Asymptomatic Volunteers
Status: RECRUITING
Conditions: Hip Disease
Interventions: OTHER: Non- contrast Magnetic Resonance Imaging (MRI) of the hip|OTHER: Magnetic Resonance Imaging (MRI) of the hip with intra-articular contrast agent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase II Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Efficacy of Prednisone Therapy in HIV-Associated Nephropathy (HIVAN)
Status: COMPLETED
Conditions: HIV Infections|AIDS-Associated Nephropathy
Interventions: DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Intrathecal Versus Intravenous Dexmedetomidine in Prostate Transurethral Resection
Status: UNKNOWN
Conditions: Dexmedetomidine|Transurethral Resection of Prostate|Analgesia
Interventions: DRUG: Control group|DRUG: Intrathecal group|DRUG: Intravenous group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Important Parameters of NIR-II Imaging in the Early Diagnosis of Lower Extremity Peripheral Artery Disease
Status: NOT_YET_RECRUITING
Conditions: Peripheral Artery Disease
Interventions: DIAGNOSTIC_TEST: The second near-infrared region (NIR-II) imaging for lower extremity peripheral artery disease (PAD)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Open-label Study of Flexible-dose Paliperidone ER (Extended Release) to Treat Adolescent Schizophrenia.
Status: COMPLETED
Conditions: Schizophrenia|Schizophrenic Disorders|Psychotic Disorders|Dementia Praecox
Interventions: DRUG: Paliperidone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Tolerability of Investigational Ocular Lubricants
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: OTHER: FID123300 ocular lubricant|OTHER: FID123301 ocular lubricant|OTHER: FID122505 ocular lubricant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of UGBRS Block and Local Infiltration
Status: COMPLETED
Conditions: Appendicitis
Interventions: PROCEDURE: UGBRSB|PROCEDURE: Local Infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Administration of 3rd Generation Cephalosporin on the Digestive Carrying of 3rd Generation Cephalosporin-resistant Enterobacteriaceae (CEF-IMPACT)
Status: UNKNOWN
Conditions: Infectious Disease - Resistant Enterobacteriaceae (Diagnosis)
Interventions: DRUG: Cefotaxime Injection|PROCEDURE: Rectal swab|DRUG: Cefotaxime/ceftriaxone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Rehabilitation in Patients With Severe Aortic Stenosis Submitted to Valvar Correction
Status: UNKNOWN
Conditions: Aortic Valve Stenosis
Interventions: BEHAVIORAL: cardiovascular rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Morphine for Analgesia in Patients With Skin Grafts
Status: WITHDRAWN
Conditions: Skin Transplantation|Pain
Interventions: OTHER: Placebo|DRUG: Morphine - .25 mg|DRUG: Morphine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of Intramuscular Injections of PLX-R18 in Subjects With Incomplete Hematopoietic Recovery Following Hematopoietic Cell Transplantation
Status: COMPLETED
Conditions: Incomplete HCT (Hematopoietic Cell Transplantation)
Interventions: BIOLOGICAL: PLX-R18
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mi Puente: My Bridge to Better Cardiometabolic Health and Well-Being
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Cardiometabolic Conditions|Behavioral Health Concerns
Interventions: BEHAVIORAL: Volunteer Peer Mentor+Behavioral Health Nurse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Allogeneic Stem Cell Transplantation vs. Conventional Therapy as Salvage Therapy for Relapsed / Progressive Patients With Multiple Myeloma After First-line Therapy
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Allogeneic Stem Cells|DRUG: carfilzomib/lenalidomide/dexamethasone (KRD)|DRUG: elotuzumab/lenalidomide/dexamethasone (ERD)|DRUG: daratumumab/bortezomib/dexamethasone (DVD)|DRUG: daratumumab/lenalidomide/dexamethasone (DRD)|DRUG: ixazomib/lenalidomide/dexamethasone (IRD)|DRUG: pomalidomide/bortezomib/dexamethasone (PVD)|DRUG: carfilzomib/daratumumab/dexamethasone (KDD)|DRUG: Autologous Stem Cells|DRUG: daratumumab/pomalidomide/dexamethasone (DPD)|DRUG: isatuximab/carfilzomib/dexamethasone (Isa-KD)|DRUG: selinexor/bortezomib/dexamethasone (SVD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GCC Agonist Signal in the Small Intestine
Status: RECRUITING
Conditions: Barrett Esophagus|Gastroesophageal Reflux Disease|Malignant Digestive System Neoplasm
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Esophagogastroduodenoscopy|DRUG: Linaclotide|DRUG: Plecanatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ferric Derisomaltose/Iron Isomaltoside and Outcomes in the Recovery of Gynecologic Oncology ERAS
Status: UNKNOWN
Conditions: Gynecologic Cancer|Anemia, Iron Deficiency|Surgery
Interventions: DRUG: Ferric Derisomaltose Injection|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 36 mm Ceramic-on-Ceramic Acetabular Cup Total Hip Replacement
Status: COMPLETED
Conditions: Non-inflammatory Degenerative Joint Disease
Interventions: DEVICE: 36 mm ceramic head on a ceramic acetabular liner|DEVICE: 28 mm ceramic head on a polyethylene acetabular liner
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TKI Therapy Based on Molecular Monitoring in Allogeneic-HSCT Recipients With Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia
Status: UNKNOWN
Conditions: Philadelphia Chromosome Positive Acute Lymphocytic Leukemia|Stem Cell Transplantation|Minimal Residual Disease
Interventions: DRUG: TKIs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Clinical Study for Two Types of Locator Attachments for Mandibular Implant Supported Overdenture
Status: COMPLETED
Conditions: Prosthesis User
Interventions: PROCEDURE: implant supported overdenture
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of High-dose IN-B001 in Healthy Subjects
Status: UNKNOWN
Conditions: Hand, Foot and Mouth Disease
Interventions: BIOLOGICAL: IN-B001 EV71 A dose|BIOLOGICAL: IN-B001 CVA16 B dose|BIOLOGICAL: IN-B001 Bivalent C dose|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Cardiopulmonary Effects and Diaphragm Function of Complete Inspiratory Muscle Training in Patients With Upper Abdominal Surgery
Status: COMPLETED
Conditions: Inspiratory Muscle Training|Postoperative Pulmonary Complications|Respiratory Muscle Function|Abdominal Surgery
Interventions: BEHAVIORAL: Inspiratory muscle training|BEHAVIORAL: Regulated care and education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tramadol Versus Celecoxib for Reducing Pain During Office Hysteroscopy in Post Menopausal Women
Status: UNKNOWN
Conditions: Hysteroscopy
Interventions: DRUG: Celecoxib|DRUG: Tramadol|DRUG: Placebo 1|DRUG: Placebo 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Nerve-sparing Techniques in Radical Prostatectomy for Oncological Outcome and Functional Recovery.
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: PROCEDURE: unilateral intrafascial resection|PROCEDURE: bilateral intrafascial resection|PROCEDURE: bilateral extrafascial resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety Study of Bimatoprost 0.01% Alone Compared With Travoprost 0.004% and Timolol 0.5% in Subjects With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: bimatoprost 0.01%|DRUG: travoprost 0.004%|DRUG: timolol 0.5%|DRUG: hypromellose 0.3%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of OPC Factor on Energy Levels
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: OPC Factor(TM)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy (SBRT) for Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Stereotactic Body Radiation Therapy (SBRT) radiation for prostate cancer utilizing the Elekta Versa or Agility System.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SNIFF - Combo INI+EMPA Trial
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Cognitive Impairment|Alzheimer Disease
Interventions: DRUG: Insulin (Humulin® R U-100)|DRUG: Empagliflozin 10 MG|DEVICE: Aptar Pharma CPS Intranasal Delivery Device|DRUG: Placebo (Insulin Diluent)|DRUG: Placebo (Capsules)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Oral Myofunctional Reeducation Methods for Children With Obstructive Sleep Apnea
Status: TERMINATED
Conditions: Obstructive Sleep Apnea
Interventions: PROCEDURE: Oral Myofunctional Therapy with exercices|PROCEDURE: Oral Myofunctional Therapy with soft oral appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Range-Finding Study to Assess the Efficacy and Safety of Multiple Dose Levels of AZD8630 in Adults With Uncontrolled Asthma at Risk of Exacerbations
Status: NOT_YET_RECRUITING
Conditions: Asthma
Interventions: DRUG: AZD8630|DRUG: Placebo|DEVICE: Inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Multisensory Stimulus Method on Pain and Physiological Parameters in Infants
Status: COMPLETED
Conditions: Multisensory Stimulation
Interventions: OTHER: Multi-sensory Stimulation Method-Mother Applying the Method to the Baby|OTHER: Multi-sensory Stimulation Method-Nurse Applying the Method to the Baby|OTHER: Breastfeeding Applied Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Randomized Controlled Trial of urinE chemiStry Guided aCute heArt faiLure treATmEnt (ESCALATE)
Status: RECRUITING
Conditions: Heart Failure|Acute Heart Failure
Interventions: DRUG: Protocolized diuretic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opioid Sparing Effect of Thoracic Epidural Analgesia for Open Upper Abdominal Surgery
Status: COMPLETED
Conditions: Hepatoma|Pancreas Cancer
Interventions: PROCEDURE: Thoracic continuous epidural analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAK-243 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Refractory Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia
Status: NOT_YET_RECRUITING
Conditions: Myelodysplastic Syndrome|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia|Refractory Chronic Myelomonocytic Leukemia|Refractory High Risk Myelodysplastic Syndrome
Interventions: DRUG: UAE Inhibitor TAK-243
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of J Stroke Myofascial Release in Patients With Planter Fasciitis
Status: COMPLETED
Conditions: Plantar Fascitis
Interventions: OTHER: J Stroke Myofascial Release|OTHER: Ischemic Release on Gastrocnemius through Dry Cupping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination of RAD001 With Carboplatin, Paclitaxel and Bevacizumab in Non-small-cell Lung Cancer (NSCLC) Patients
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: RAD001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Superiority Trial Between Sotair® Device Attached to Manual Resuscitator Versus Ventilation Alone
Status: RECRUITING
Conditions: Airway Management|Respiration, Artificial
Interventions: DEVICE: Adult Sotair Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Premixed Insulin Treatment in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DEVICE: Professional flash glucose mornitoring|DEVICE: Personal flash glucose mornitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT