pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of an Interactive Risk Information Tool to Increase COVID-19 Vaccination Incidence in Vaccine-hesitant People
Status: RECRUITING
Conditions: COVID-19 Infection
Interventions: BEHAVIORAL: Simulation|BEHAVIORAL: Text
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Glucocorticosteroid Therapy on Drug-induced Liver Injury: a Prospective Non-randomized Concurrent Control Trial
Status: RECRUITING
Conditions: Drug-induced Liver Injury
Interventions: DRUG: Glucocorticoids+hepatoprotectant|DRUG: hepatoprotectant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer
Status: NOT_YET_RECRUITING
Conditions: Nasopharyngeal Cancer Recurrent
Interventions: DRUG: Toripalimab|DRUG: Cisplatin|DRUG: Gemcitabine|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Covered CP Stents for the Prevention or Treatment of Aortic Wall Injury Associated With Coarctation of the Aorta
Status: COMPLETED
Conditions: Aortic Coarctation
Interventions: DEVICE: Treatment of Aortic Wall Injury
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Maintenance With Azacitidine in MDS Patients
Status: TERMINATED
Conditions: Leukemia, Myelocytic, Acute|Myelodysplastic Syndromes
Interventions: DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating High Flow Humidification Therapy in Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DEVICE: High-Flow, 20 LPM (via Optiflow cannula)|DEVICE: Low FLow, 5 LPM (via Optiflow cannula)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Eltrombopag For Secondary Poor Graft Function Post Allogeneic Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Poor Graft Function
Interventions: DRUG: Eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Risk Myelodysplasia Treated by Azacytidine : Genetic and Epigenetic (MYRAGE)
Status: UNKNOWN
Conditions: High-risk Myelodysplastic Syndromes With Excess Blasts
Interventions: DIAGNOSTIC_TEST: Myelogram
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study of Bevacizumab in Previously Untreated Extensive-Stage Small Cell Lung Cancer (SALUTE)
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Bevacizumab|DRUG: Chemotherapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetics, Pharmacodynamics and Safety Study of Single Dose of Rivaroxaban in Participants With End-Stage Renal Disease (ESRD) on Maintenance Hemodialysis
Status: COMPLETED
Conditions: End-Stage Renal Disease
Interventions: DRUG: Rivaroxaban 15 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: European Study in Bone Sarcoma Patients Over 40 Years
Status: COMPLETED
Conditions: Spindle Cell Sarcoma of Bone|Osteosarcoma
Interventions: DRUG: Doxorubicin+cisplatin+ifosfamide|DRUG: Doxorubicin+cisplatin+ifosfamide+methotrexate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of Totally Laparoscopic Resection With Natural Orifice Specimen Extraction (NOSE) for Rectosigmoid Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: PROCEDURE: transrectal specimen extraction|PROCEDURE: Conventional laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Maintenance Temozolomide Versus Observation in Stable or Responding Stage III/IV Non-Small Cell Lung Cancer Patients (Study P05146)
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung|Adenocarcinoma|Carcinoma, Large Cell|Carcinoma, Squamous Cell
Interventions: DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Irinotecan for Patients With Primary Brain Tumors and Progression After Standard Therapy
Status: COMPLETED
Conditions: Brain Neoplasms|Glioma
Interventions: DRUG: Bevacizumab|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study For Orally-Disintegrating Tablet Of Sildenafil
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Viagra|DRUG: sildenafil ODT|DRUG: sildenafil ODT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Inhibition of Reverse Transcription in Aicardi-Goutières Syndrome
Status: COMPLETED
Conditions: Aicardi-Goutières Syndrome
Interventions: DRUG: Abacavir (ABC)|DRUG: Lamivudine (3TC)|DRUG: Abacavir (ABC)+Lamivudine (3TC)+Zidovudine (AZT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low FODMAP (Fermentable Oligo-,di-,Mono-saccharides and Polyols) Versus Gluten-free Diet in Pediatric IBS Patients; a Cross-over Randomized Trial.
Status: UNKNOWN
Conditions: Effects of Low FODMAP Diet Versus Gluten-free Diet on IBS Symptoms in Children
Interventions: OTHER: low FODMAP diet vs Gluten free diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: AT1001 for the Treatment of COVID-19 Related MIS-C
Status: TERMINATED
Conditions: Covid19|Multisystem Inflammatory Syndrome in Children
Interventions: DRUG: Larazotide Acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Xalatan (Latanoprost) to Apo-latanoprost and Co-latanoprost in the Treatment of Glaucoma
Status: UNKNOWN
Conditions: POAG|Primary Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Xalatan|DRUG: Apo-Latanoprost|DRUG: Co-Latanoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Approach to Surveillance of Gastric Lesions
Status: UNKNOWN
Conditions: Intestinal Metaplasia of Gastric Mucosa|Gastric Dysplasia|Gastric Cancer|Atrophic Gastritis
Interventions: DIAGNOSTIC_TEST: Mucosal Irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Take a STAND 4 Health: A Sedentary Behavior Reduction Intervention
Status: COMPLETED
Conditions: Blood Pressure
Interventions: BEHAVIORAL: Take a STAND 4 Health
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Non-Invasive Aortic Ambulatory Blood Pressure Monitoring for The Detection of Target Organ Damage in The Chinese Population
Status: UNKNOWN
Conditions: Blood Pressure|Cardiovascular Risk Factor|Target Organ Damage|Cardiovascular Events|Cardiovascular Mortality|Overall Mortality
Interventions: OTHER: No intervention in this study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Olaparib and High-Dose Chemotherapy in Treating Patients With Relapsed or Refractory Lymphomas Undergoing Stem Cell Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Diffuse Large B-Cell Lymphoma|Recurrent T-Cell Non-Hodgkin Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Hodgkin Lymphoma|Refractory T-Cell Non-Hodgkin Lymphoma
Interventions: DRUG: Busulfan|DRUG: Gemcitabine|DRUG: Melphalan|DRUG: Olaparib|PROCEDURE: Peripheral Blood Stem Cell Transplantation|OTHER: Pharmacokinetic Study|BIOLOGICAL: Rituximab|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Efficacy and Safety of OTL-203 in Subjects With MPS-IH Compared With Standard of Care With Allogeneic HSCT
Status: RECRUITING
Conditions: MPS-IH (Hurler Syndrome)
Interventions: GENETIC: Experimental: OTL-203|GENETIC: Active Comparator: Allo-HSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Adherence Study of Antipsychotic Medication in Outpatients With Schizophrenia or Schizoaffective Disorder
Status: UNKNOWN
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DEVICE: Medication Event Monitoring System (MEMS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety and Immunogenicity Study in Long-term Treatment of Eculizumab (JSC "GENERIUM", Russian Federation)
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: BIOLOGICAL: Eculizumab (JSC GENERIUM, Russia)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-39439335 in Patients With Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Placebo|DRUG: JNJ-39439335|DRUG: Naproxen|DRUG: JNJ-39439335
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Rivastigmine With Add-on Memantine in Patients With Probable Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Rivastigmine, memantine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Appetite Regulation in Older-Aged Obese Individuals
Status: COMPLETED
Conditions: Obesity|Aging
Interventions: DIETARY_SUPPLEMENT: 3-day diet Run-in|PROCEDURE: fMRI|PROCEDURE: Intravenous catheter placed for blood draws
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Infant Formulas Containing a New Fat Blend or the New Fat Blend Plus Fiber in Healthy Term Infants
Status: COMPLETED
Conditions: Bottle Feeding
Interventions: DIETARY_SUPPLEMENT: Infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PUVA Versus PUVA + IFN Alpha 2a in Mycosis Fungoides
Status: TERMINATED
Conditions: Cutaneous T-Cell Lymphoma (Mycosis Fungoides)
Interventions: DRUG: PUVA (8MOP + UVA) + IFN|DRUG: PUVA (8-MOP + UVA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy And Safety Of Thoracoscopic Cryobiopsy In Patients With Undiagnosed Exudative Pleural Effusion
Status: COMPLETED
Conditions: Pleura; Exudate
Interventions: DEVICE: Thoracoscopy forceps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Coping Training for People With HIV Experiencing Treatment Side Effects (The Balance Project)
Status: COMPLETED
Conditions: HIV Infections
Interventions: BEHAVIORAL: Cognitive behavioral coping effectiveness training|BEHAVIORAL: Standard care|BEHAVIORAL: Single group workshop on coping effectiveness training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intraoperativ Testing of Scapholunate Instability in Radius Fracture
Status: UNKNOWN
Conditions: Radius; Dislocation Distal|Scapholunate Dissociation
Interventions: DIAGNOSTIC_TEST: dynamic functional testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Direct and Reversed Dorsal Digito-metacarpal Flaps: A Review of 24 Cases
Status: COMPLETED
Conditions: Finger Injuries|Soft Tissue Injuries
Interventions: PROCEDURE: Dorsal digito-metacarpal flap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Recovery in Stroke Using PAP Study
Status: RECRUITING
Conditions: Ischemic Stroke|Obstructive Sleep Apnea
Interventions: DEVICE: PAP|BEHAVIORAL: HLE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Rehabilitation in Peripheral Arterial Disease With Claudication: Effects of a Treadmill Training With Active Recovery
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Claudication
Interventions: PROCEDURE: experimental rehabilitation program|PROCEDURE: conventional rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gefitinib in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Bronchoalveolar Cell Lung Cancer|Recurrent Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: gefitinib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of a Modular Control to Range System in Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: Closed Loop Control (CLC)|DEVICE: Open Loop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Diet, Physical Activity and Breastfeeding Intervention on Maternal Nutrition, Offspring Growth and Development
Status: UNKNOWN
Conditions: Obesity|Weight Gain|Metabolic Diseases|Birth Weight|Infant Nutrition Disorders
Interventions: BEHAVIORAL: Normative Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: First-in-Human Dose Escalation Study of M201-A in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: M201-A Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Immune Response and Safety of an RSV Vaccine When Given to Adults 18 Years of Age and Above Who Received Lung or Kidney Transplant and Are at an Increased Risk of Respiratory Syncytial Virus Lower Respiratory Tract Disease and Compared to Healthy Adults 50 Years of Age and Above
Status: ACTIVE_NOT_RECRUITING
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSVPreF3 OA Investigational Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Scapulothoracic Exercises on Postural Stability, Proprioception, Muscular Features and Mandibular Functions
Status: COMPLETED
Conditions: Temporomandibular Joint Dysfunction Syndrome|Forward Head Posture
Interventions: OTHER: Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Inclisiran in Chinese Participants With Elevated Serum LDL-C
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: 100 mg inclisiran sodium (equivalent to 94.5 mg inclisiran)|DRUG: Placebo|DRUG: 300 mg inclisiran sodium (equivalent to 284 mg inclisiran)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Effectiveness of Intranasal Administration of Temozolomide in Patients With Glioblastoma
Status: COMPLETED
Conditions: Glioma, Malignant|Gliosarcoma|Astrocytoma of Brain
Interventions: DRUG: Intranasal Modified Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety/Efficacy of a Single Pre-Op Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery
Status: COMPLETED
Conditions: Postsurgical Pain
Interventions: DRUG: AYX1 Injection 660 mg / 6 mL|DRUG: AYX1 Injection 1100 mg / 10 mL|DRUG: Placebo Injection 6 mL|DRUG: Placebo Injection 10 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Are There Changes in the Nerve Fiber Layer (NFL) After Lowering of Eye Pressure?
Status: COMPLETED
Conditions: Glaucoma
Interventions: DIAGNOSTIC_TEST: Optical Coherence Tomography (OCT)|DIAGNOSTIC_TEST: Visual evoked potential (VEP)|DIAGNOSTIC_TEST: Humphrey Visual Field (HVF)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Restoring Energy With Sub-symptom Threshold Optimized Rehabilitation Exercise for Long COVID
Status: COMPLETED
Conditions: Long Covid19|Exercise Intolerance|Riboflavin-Responsive
Interventions: BEHAVIORAL: Restoring Energy with Sub-symptom Threshold Aerobic Rehabilitation Exercise|BEHAVIORAL: Light Stretching/Breathing Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Gut, Liver And Metabolome in Human Immunodeficiency Virus and Non Alcoholic Fatty Liver Disease
Status: RECRUITING
Conditions: HIV|Non-Alcoholic Fatty Liver Disease|Metabolic-Associated Steatotic Liver Disease
Interventions: DIETARY_SUPPLEMENT: Prebiotic|DIETARY_SUPPLEMENT: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implications of Circadian Variation of Human Endocannabinoid Levels on Obesity Risk
Status: NOT_YET_RECRUITING
Conditions: Obesity
Interventions: BEHAVIORAL: Early Total Caloric Intake|BEHAVIORAL: Late Total Caloric Intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Interest of Whole-body MRI Correlated to Spreading Sequences for Staging Neuroendocrine Tumors
Status: UNKNOWN
Conditions: Neuroendocrine Tumors With Metastasis
Interventions: DEVICE: Whole-body diffusion- weighted MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Combination Chemotherapy in Treating Patients With Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRTX-100-203 Open-Label, Dose Escalation Study in Adult Patients With ITP
Status: TERMINATED
Conditions: Immune Thrombocytopenia
Interventions: DRUG: PRTX-100|DRUG: PRTX-100|DRUG: PRTX-100|DRUG: PRTX-100|DRUG: PRTX-100
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Microbiomes of Postmenopausal Women Looking for Outcomes and Response to Estrogen Therapy
Status: COMPLETED
Conditions: Female Urogenital Diseases|Vaginal Atrophy|Postmenopausal Atrophic Vaginitis|Genitourinary Disease|Postmenopausal Symptoms
Interventions: DRUG: Conjugated Estrogens Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Yttrium-90 Radioembolization + Nivolumab for Liver + Extra-hepatic Metastases From Colorectal Cancer
Status: WITHDRAWN
Conditions: Metastatic Colorectal Cancer
Interventions: RADIATION: yttrium-90 radioembolization|DRUG: Phase Ib - nivolumab|DRUG: Phase II - nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BCG Against Covid-19 for Prevention and Amelioration of Severity Trial (BAC to the PAST)
Status: WITHDRAWN
Conditions: Covid19
Interventions: DRUG: BCG Vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dexmedetomidine-Propofol Versus Ketamine-Propofol for Sedation of CT Guided Bone Biopsy
Status: COMPLETED
Conditions: Sedation
Interventions: DRUG: Dexmedetomidine-propofol|DRUG: Ketamine-Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Randomized Control Trial Copper Intrauterine Device and Depo-medroxyprogesterone Acetate (DMPA) of HIV+ Women in Malawi
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Copper IUD|DRUG: Depo Medroxyprogesterone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Double Blind Study Evaluating Paclitaxel With and Without RAD001 in Patients With Gastric Carcinoma After Prior Chemotherapy
Status: COMPLETED
Conditions: Advanced Gastric Cancer|Esophagogastric Junction Cancer
Interventions: DRUG: Paclitaxel|DRUG: RAD001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sodium Fluorescein-Guided Resection of Pediatric Neurosurgical Tumors
Status: TERMINATED
Conditions: Pediatric Neurosurgical Tumors
Interventions: DRUG: Sodium Fluorescein|DEVICE: Microscopic Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Self-help App and Wellbeing
Status: COMPLETED
Conditions: Anxiety and Worry
Interventions: BEHAVIORAL: Anxiety Application|BEHAVIORAL: Procrastination Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Aquatic vs. Land Locomotor Training Overground Locomotor Training in Improving Ambulatory Function and Health-Related Quality of Life
Status: TERMINATED
Conditions: Spinal Cord Injury
Interventions: OTHER: Aquatic Locomotor Training|OTHER: Land Locomotor Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Absorption, Metabolism, and Excretion and the Absolute Bioavailability of YH12852
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: YH12852|DRUG: 14C-labeled YH12852
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Target-controlled Infusion of Propofol and Remifentanil for Postoperative Sedation Guided by the Bispectral Index
Status: COMPLETED
Conditions: Postoperative Sedation
Interventions: DEVICE: Closed-loop anesthesia system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telerehabilitation-based Motor Imagery Training in Children With Duchenne Muscular Dystrophy
Status: NOT_YET_RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: PROCEDURE: telerehabilitation-based motor imagery training|PROCEDURE: telerehabilitation-based physiotheraphy training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PREVENTion With Sglt-2 Inhibition of Acute Kidney Injury in Intensive Care
Status: RECRUITING
Conditions: Acute Kidney Injury
Interventions: DRUG: Dapagliflozin 10mg Tab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: the Influence of Virtual Reality Approach on Phantom Pain in Trans Tibial Amputation
Status: ACTIVE_NOT_RECRUITING
Conditions: Phantom Pain Following Amputation of Lower Limb
Interventions: DEVICE: Virtual Reality|DEVICE: Transcutaneous Electrical Nerve Stimulation (TENS)|DEVICE: Mirroring Therapy|OTHER: Phantom Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double-Blind, Single-Dose, Efficacy and Safety Study of Test Acetaminophen Tablet in Postoperative Dental Pain
Status: COMPLETED
Conditions: Post-operative Dental Pain
Interventions: DRUG: Test acetaminophen|DRUG: Commercial acetaminophen|DRUG: Commercial ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label, Multicenter, Two-Part, Phase 1 Study to Characterize Effects of a Moderate CYP3A Inhibitor on PK of Tazemetostat, Effects of Tazemetostat on PK of CYP2C8 and CYP2C19 Substrates, and Effect of Increased Gastric pH on PK of Tazemetostat in B-cell Lymphoma or Advanced Solid Tumor Patients
Status: COMPLETED
Conditions: Diffuse Large B Cell Lymphoma|Primary Mediastinal Lymphoma|Mantle Cell Lymphoma|Advanced Solid Tumor|Marginal Zone Lymphoma
Interventions: DRUG: Tazemetostat|DRUG: Fluconazole|DRUG: Omeprazole|DRUG: Repaglinide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Percutaneous Transluminal Renal Angioplasty of Atherosclerotic Renal Artery Stenosis in High-Risk Patients.
Status: RECRUITING
Conditions: Renovascular Hypertension|Renovascular Hypertension With Renal Failure|Heart Failure|Renal Artery Stenosis Atherosclerotic|Percutaneous Transluminal Angioplasty
Interventions: PROCEDURE: Renal artery stenting|PROCEDURE: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of Evogliptin 5 mg and Pioglitazone 30 mg
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Evogliptin, Pioglitazone, Evogliptin+Pioglitazone|DRUG: Pioglitazone, Evogliptin, Evogliptin+Pioglitazone|DRUG: Evogliptin, Evogliptin+Pioglitazone, Pioglitazone|DRUG: Pioglitazone, Evogliptin+Pioglitazone, Evogliptin|DRUG: Evogliptin+Pioglitazone, Evogliptin, Pioglitazone|DRUG: Evogliptin+Pioglitazone, Pioglitazone, Evogliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Treatment of Atopic Dermatitis by a Full-Body Blue Light Device
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DEVICE: Full Body Blue Light Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Defining the Serum Ferritin Concentration in Kenyan Women at Which the Body Senses Iron Depletion and Begins to Upregulate Iron Absorption
Status: COMPLETED
Conditions: Iron-deficiency|Ferritin Threshold|Iron Absorption|Stable Iron Isotopes
Interventions: OTHER: Isotopically labelled iron sulfate 15mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase 1/2 Study of HS-410 in Patients With Non-Muscle Invasive Bladder Cancer After TURBT
Status: TERMINATED
Conditions: Bladder Cancer
Interventions: BIOLOGICAL: HS-410|BIOLOGICAL: Placebo|BIOLOGICAL: BCG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: trūFreeze® Spray Cryotherapy Patient Registry
Status: COMPLETED
Conditions: Barrett Esophagus|Esophageal Dysplasia|Esophageal Neoplasm|Esophageal Stenosis|Bronchial Neoplasm|Stenosis of Bronchus or Trachea
Interventions: DEVICE: truFreeze Spray Cryotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Adalimumab in Patients With Axial Spondyloarthritis
Status: COMPLETED
Conditions: Axial Spondyloarthritis
Interventions: BIOLOGICAL: Adalimumab|BIOLOGICAL: Placebo|BIOLOGICAL: Open-label Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vacuum Device for Hemostasis in Obstetrics and Gynecology
Status: COMPLETED
Conditions: Primary Postpartum Hemorrhage|Administration of Sulprostone|Vaginal Childbirth
Interventions: DEVICE: Hemostatic Intra-Uterine suction cup
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acceptance and Commitment Therapy Based Group Psychoeducation for Nursing Students
Status: ACTIVE_NOT_RECRUITING
Conditions: Psychological Flexibility|Somatic Symptom
Interventions: OTHER: Acceptance and commitment therapy based group psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hepar-P Study to Evaluate the Safety and Efficacy of a Standardised Extract of Phyllanthus Niruri for the Treatment of Non-alcoholic Fatty Liver Disease
Status: UNKNOWN
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DRUG: Hepar-P|DRUG: Placebo for Hepar-P
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of BGG492 as Adjunctive Treatment in Patients With Partial Onset Seizures
Status: COMPLETED
Conditions: Partial Onset Seizures
Interventions: DRUG: Investigational new drug, company code: BGG492|DRUG: Placebo|DRUG: Investigational new drug, company code: BGG492
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Reduction and Changes in Upper Limb Function Produced by Different Treatments in Carpal Tunnel Syndrome
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Median nerve neural mobilization|DRUG: Ibuprofen Arginine|DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Dexmedetomidine During Weaning From Analgesia and Sedation in PICU (TIP-15-01)
Status: TERMINATED
Conditions: Withdrawal Syndrome
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Patients With Blepharitis and Facial Rosacea
Status: COMPLETED
Conditions: Blepharitis|Meibomianitis|Dry Eye
Interventions: DRUG: COL-101 (doxycycline, USP) capsules|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cantharidin Application in Molluscum Patients
Status: COMPLETED
Conditions: Molluscum Contagiosum
Interventions: COMBINATION_PRODUCT: VP-102 - Cantharidin, Topical Film Forming Solution|COMBINATION_PRODUCT: Placebo -Topical Film Forming Solution without VP-102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Understanding the Role of Gut Microbiota in Hyperphagia in Prader-Willi Syndrome
Status: COMPLETED
Conditions: Prader-Willi Syndrome|Obesity
Interventions: DRUG: NBT-NM108
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostics of Coronavirus Disease 2019 Cardiovascular Complications
Status: ENROLLING_BY_INVITATION
Conditions: COVID-19|Endothelial Function|Diastolic Dysfunction|Oxygen Consumption|Quality of Life|Exercise Tolerance
Interventions: DIAGNOSTIC_TEST: Portable cardiac monitor "CardioQvark"|DIAGNOSTIC_TEST: Cardiorespiratory stress test|DIAGNOSTIC_TEST: Analysis of exhaled air using the Compact PTR-MS proton mass spectrometer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Safety and Efficacy of Oral Lenvatinib in Medullary and Iodine-131 Refractory, Unresectable Differentiated Thyroid Cancers, Stratified by Histology
Status: COMPLETED
Conditions: Thyroid Cancer
Interventions: DRUG: Lenvatinib (DTC Cohort)|DRUG: Lenvatinib (MTC Cohort)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Performance of the Steroid-Releasing S8 Sinus Implant
Status: COMPLETED
Conditions: Chronic Sinusitis
Interventions: DRUG: S8 Sinus Implant (mometasone furoate, 1350 mcg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Efficacy of Granulocyte Colony Stimulating Factor Versus Standard Medical Therapy in Patients of Decompensated Cirrhosis
Status: COMPLETED
Conditions: Cirrhosis
Interventions: DRUG: Granulocyte Colony Stimulating Factor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pre- and Post-Operative Oral Dextromethorphan
Status: COMPLETED
Conditions: Efficacy of Dextromethorphan|Morphine Consumption|Pain
Interventions: DRUG: pre-operatively followed by 30 mg three times per day after surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Role of Intralipid in Management of Organophosphorus Poisoning
Status: NOT_YET_RECRUITING
Conditions: Organophosphorus Poisoning
Interventions: DRUG: Intralipid, 20% Intravenous Emulsion|DRUG: Intravenous Atropine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Bioavailability of Two Forms of Vitamin C
Status: COMPLETED
Conditions: Bioavailability
Interventions: DIETARY_SUPPLEMENT: calcium ascorbate|DIETARY_SUPPLEMENT: ascorbic acid|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects Antioxidants Supplementation on Muscular Function Patients Facioscapulohumeral Dystrophy (FSHD)
Status: COMPLETED
Conditions: Facioscapulohumeral Muscular Dystrophy
Interventions: PROCEDURE: Taking of blood|DIETARY_SUPPLEMENT: needle biopsy of the vastus lateralis muscle|DIETARY_SUPPLEMENT: Vit C Vit E Zn Se|DIETARY_SUPPLEMENT: Placebo Vit E Placebo Vit C Zn Se
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate Drug-drug Interaction of ZX-7101A Tablets and Oseltamivir Phosphate Capsules in Healthy Adult Subjects
Status: RECRUITING
Conditions: Drug Interaction
Interventions: DRUG: ZX-7101A|DRUG: Oseltamivir|DRUG: ZX-7101A and Oseltamivir|DRUG: ZX-7101A|DRUG: Oseltamivir|DRUG: ZX-7101A and Oseltamivir|DRUG: ZX-7101A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of BI 695501 Administered Via Prefilled Syringe or Autoinjector
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 695501 prefilled syringe|DRUG: BI 695501 autoinjector
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: I Can Move With Purpose Now! A Pilot Lifestyle Intervention Study in Myeloproliferative Neoplasm Patients
Status: RECRUITING
Conditions: Myeloproliferative Disorders|Leukemia
Interventions: BEHAVIORAL: Cardiac Lifestyle Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness Of Computer-Based Cognitive Training in Age-Related Cognitive Decline
Status: COMPLETED
Conditions: Age-related Cognitive Decline
Interventions: OTHER: Aerobic Exercise and Computerized Cognitive Training|OTHER: Conventional Exercises and Brain health lectures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Diagnostic Yield and Safety of the ProCore vs Conventional EBUS-TBNA Needle in Subjects With Suspected Sarcoidosis
Status: COMPLETED
Conditions: Sarcoidosis
Interventions: DEVICE: Procore biopsy needle|DEVICE: Conventional biopsy needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Talsaclidine in Patients With Mild to Moderate Dementia of Alzheimer Type
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Talsaclidine 6 mg|DRUG: Talsaclidine 12 mg|DRUG: Talsaclidine 24 mg|DRUG: Talsaclidine 36 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of 2DG With Stereotactic Radiosurgery
Status: WITHDRAWN
Conditions: Intracranial Neoplasms|Neoplasm Metastasis
Interventions: DRUG: 2-deoxyglucose (2DG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Trajectory Nor-epinephrine Infiltration Reduce Blood Loss During Percutaneous Nephrolithotomy (PCNL)?
Status: COMPLETED
Conditions: Blood Loss, Surgical
Interventions: PROCEDURE: Nor-Epinephrine injection versus saline during PCNL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Air-Q® SP Versus Williams Intubating Airway for Single-Operator FOI
Status: COMPLETED
Conditions: Intubation; Difficult or Failed|Laryngeal Masks
Interventions: DEVICE: air-Q® SP|DEVICE: Williams Airway Intubator (WA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Lenalidomide/Dexamethasone With or Without Elotuzumab for Newly Diagnosed MM Patients in Japan
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: Dexamethasone|BIOLOGICAL: Elotuzumab (BMS-901608)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Safety, Tolerability and Pharmacokinetics of Multiple Doses of AZD8566.
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: AZD8566|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluate the Efficacy and Safety of NYX-2925 in Subjects With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: NYX-2925|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Better Nights, Better Days for Children With Neurodevelopment Disorders
Status: UNKNOWN
Conditions: Nonorganic Insomnia|Neurodevelopmental Disorders|Primary Insomnia
Interventions: BEHAVIORAL: BNBD-NDD Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Refractory Acute Graft-Versus-Host Disease by Sequential Infusion of Allogenic Mesenchymal Stem Cell.
Status: COMPLETED
Conditions: Chronic Graft-Versus-Host Disease
Interventions: GENETIC: Allogenic Mesenchymal Stem Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Stress in Adolescents and Young Adults With Type 1 Diabetes to Improve Diabetes Care
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Mindfulness Based Stress Reduction|BEHAVIORAL: Diabetes Support and Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Distraction Methods On Fear And Anxiety In Children Before The Covid 19 Test
Status: COMPLETED
Conditions: Anxiety|Fear
Interventions: BEHAVIORAL: The Kaleidescope|BEHAVIORAL: The visual illusion cards
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Testing Scalable, Single-Session Interventions for Adolescent Depression in the Context of COVID-19
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Supportive Therapy SSI|BEHAVIORAL: Behavioral Activation SSI|BEHAVIORAL: Growth Mindset SSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long COVID and Post-exertional Pulmonary Diffusion
Status: COMPLETED
Conditions: Long COVID|Breathlessness|Exercise Intolerance|Alveolar Lung Disease|Pulmonary Gas Exchange
Interventions: DIAGNOSTIC_TEST: Lung volumes, spirometry and standard single-breath DLCO were measured at rest while combined DLNO and DLCO were measured at rest and post-exercise
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Homeopathic Cold Remedy for Children Study
Status: COMPLETED
Conditions: Upper Respiratory Tract Infections
Interventions: DRUG: Hyland's Cold 'n Cough 4 kids|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Aerosolised Colistin in Ventilator Associated Pneumonia
Status: COMPLETED
Conditions: Pneumonia, Ventilator-Associated
Interventions: DRUG: AS colistin and "imipenem"|DRUG: IV colistin " and "imipenem" .|DRUG: AS colimycin (colistin)|DRUG: IV colimycin (colistin)|DRUG: AS colistin and imipenem|DRUG: IV colistin and imipenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Single and Multiple Ascending Dose Study of COR588
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: COR588|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Differential Responses to Drugs and Sweet Tastes
Status: COMPLETED
Conditions: Bipolar II Disorder
Interventions: DRUG: Placebo oral capsule|DRUG: d-amphetamine 10 mg oral capsule|DRUG: d-amphetamine 20 mg oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Robot-assisted Radical Prostatectomy Technique on Short-term Continence Recovery
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: PROCEDURE: Retzius sparing radical prostatectomy|PROCEDURE: Vattikuti Urology Institute radical prostatectomy|DEVICE: da Vinci Surgical System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Re-exposure Study of Pegloticase Intravenous (i.v.) in Symptomatic Gout Patients
Status: COMPLETED
Conditions: Chronic Gout Refractory to Conventional Therapy
Interventions: DRUG: pegloticase 8 mg i.v.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT