pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Estimating Length of Endotracheal Tube Insertion Using Gestational Age or Nasal-Tragus Length in Newborn Infants
Status: UNKNOWN
Conditions: Endotracheal Tube Tip Position|Bronchopulmonary Dysplasia|Pneumothorax|Death|Duration, Ventilator
Interventions: OTHER: Gestational Age Chart Method|OTHER: Nasal-Tragus Length Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I/II Study of MGCD0103 (MG-0103) in Combination With Gemcitabine
Status: COMPLETED
Conditions: Tumors
Interventions: DRUG: MGCD0103|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulsed Field Ablation (PFA) vs Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atrial Fibrillation
Status: RECRUITING
Conditions: Persistent Atrial Fibrillation
Interventions: DEVICE: FARAPULSE™ Pulsed Field Ablation (PFA) System|DRUG: Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, Dofetilide, and Dronedarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Follow-Up Study of Human Stem Cells Transplanted in Subjects With Connatal Pelizaeus-Merzbacher Disease (PMD)
Status: COMPLETED
Conditions: Pelizaeus-Merzbacher Disease|PMD
Interventions: BIOLOGICAL: HuCNS-SC transplant in the lead-in phase
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TACE vs TACE+SBRT for Unresectable Hepatocellular Cancer
Status: UNKNOWN
Conditions: Carcinoma, Hepatocellular
Interventions: RADIATION: SBRT|PROCEDURE: TACE|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cervical Lidocaine Spray on Pain Relief During Manual Vacuum Aspiration
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain, Procedural|Lidocaine|Obstetric Surgical Procedures
Interventions: DRUG: 10 % lidocaine spray without adrenaline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Sleep Patterns in Patients Affected by Lymphangioleiomiomatosis
Status: UNKNOWN
Conditions: Lymphangioleiomyomatosis|Sleep Disorder|Sleep Apnea Syndromes|Hypopnea Syndrome
Interventions: DIAGNOSTIC_TEST: LAM patients underwent PSG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study on the Safety of BAY1817080 How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug Given to Participants With Moderate Renal Impairment and End Stage Renal Disease Requiring Dialysis Compared With Matched Participants With Normal Renal Function
Status: COMPLETED
Conditions: Endometriosis Related Pain|Overactive Bladder|Diabetic Neuropathic Pain|Refractory or Unexplained Chronic Cough
Interventions: DRUG: BAY1817080
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Relationship of Platelet Micro-RNA Expression and Platelet Reactivity in Patients Under Clopidogrel or Ticagrelor Treatment
Status: COMPLETED
Conditions: PRU|miRNA
Interventions: PROCEDURE: miRNA within 24hr|PROCEDURE: miRNA after 1 week|PROCEDURE: miRNA after 1 month
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Does Co-administration of Lactate to an Oral Glucose Tolerance Test Lower the Glucose Response?
Status: NOT_YET_RECRUITING
Conditions: PreDiabetes|Metabolic Syndrome|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Lactate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: MOBILE Trial. Mechanical and Oral Antibiotic Bowel Preparation Versus no Bowel preparatIon for eLEctive Colectomy - a Multicenter, Prospective, Randomized, Controlled Trial.
Status: UNKNOWN
Conditions: Colorectal Surgery
Interventions: DRUG: neomycin, metronidazole, polyethylene glycol (PEG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Shoulder Dislocations Treated With Button Plates and Non-absorbable Suture Anchor
Status: COMPLETED
Conditions: Shoulder Dislocation
Interventions: DEVICE: button plates fixation system|DEVICE: Non-absorbable Suture Anchor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Atrial Fibrillation Symptoms and Pain Sensitization
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DIAGNOSTIC_TEST: Quantitative sensory testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of AK104 Plus Platinum-containing Chemotherapy±Bevacizumab as First-line Treatment for Persistent, Recurrent, or Metastatic Cervical Cancer
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: BIOLOGICAL: AK104|DRUG: paclitaxel|DRUG: carboplatin|DRUG: cisplatin|DRUG: bevacizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)
Status: COMPLETED
Conditions: Acute Leukemia|Chronic Myelogenous Leukemia|Myelodysplasia|Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma|Lymphoma, B-Cell|Lymphoma, Follicular|Lymphoma, Large B-Cell, Diffuse|Hodgkin's Lymphoma
Interventions: DRUG: Tacrolimus (ARM with Methotrexate)|DRUG: Tacrolimus (ARM with MMF and Cyclophosphamide)|DRUG: Methotrexate (ARM with Maraviroc)|DRUG: Methotrexate (ARM with Bortezomib)|DRUG: Maraviroc|DRUG: Bortezomib|DRUG: Mycophenolate mofetil|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Early Diabetes Intervention Program
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Acarbose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Xenogenous Collagen Matrix Graft With or Without Enamel Matrix Proteins Derivative for Root Coverage
Status: COMPLETED
Conditions: Gingival Recession
Interventions: DEVICE: Mucograft|DEVICE: Emdogain|PROCEDURE: Coronally Advanced flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prebiotics and Mental Health: Behavioural
Status: COMPLETED
Conditions: Emotion Regulation|Anxiety
Interventions: DIETARY_SUPPLEMENT: GOS|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Isolation of Volatile Organic Compounds (VOCs) Related to the Olfactory Signature of Breast Cancer.
Status: COMPLETED
Conditions: Breast Cancer|Surgery
Interventions: DIAGNOSTIC_TEST: Sorbstar®|DIAGNOSTIC_TEST: Dog Detection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: DRUG RELEASING BALL vs. PHARMACOACTIVE STENT IN LARGE VESSELS: MORPHOLOGICAL ANALYSIS AND FUNCTION VASOMOTOR (DEBORA STUDY) IN LARGE VESSELS: MORPHOLOGICAL ANALYSIS AND FUNCTION VASOMOTOR (DEBORA STUDY)
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: Drug Coated Balloon (DCB)|DEVICE: Drug Eluting Stent (DES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of in Vitro Devices on Self-collected Vaginal Swab and Urine Sample for Testing of Human Papilloma Virus
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia Grade 2/3|Neoplasm Cervix|Carcinoma in Situ|Carcinoma Cervix Uterine|Neoplasms|Neoplasms by Histologic Type
Interventions: DEVICE: Self-Collecting Devices|DIAGNOSTIC_TEST: In Vitro Diagnostic Assays
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluate the Effectiveness and Toxicity of Adjuvant Ultra-hypofractionated Radiotherapy for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer Female
Interventions: RADIATION: adjuvant ultra-hypofractionated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System
Status: RECRUITING
Conditions: Mitral Regurgitation
Interventions: DEVICE: Transcatheter Mitral Valve Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulsed Electromagnetic Field Therapy for TMJ Dysfunction After Facial Penetrating Injury
Status: COMPLETED
Conditions: TMJ Disorder
Interventions: DEVICE: Pulsed Electromagnetic Field therapy (PEMFT)|OTHER: TMJ physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Neuromuscular Block During General Anaesthesia in Robotic Surgery
Status: COMPLETED
Conditions: Observation of Neuromuscular Block|Complication of Ventilation Therapy|Postoperative Recovery
Interventions: DRUG: Sugammadex|DRUG: Neostigmine, Atropin Biotika
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Strategies Using Off-Patent Antibiotics for Methicillin Resistant S. Aureus "STOP MRSA"
Status: COMPLETED
Conditions: Staphylococcal Infection
Interventions: DRUG: Cephalexin|DRUG: Clindamycin|OTHER: Placebo|DRUG: Trimethoprim-sulfamethoxazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety, Tolerability and Pharmacokinetics of ASC42 in Chinese Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ASC42|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: To Identify the Immunogenicity and Safety of QIV in Children Aged 3-8 Years
Status: UNKNOWN
Conditions: Influenza
Interventions: BIOLOGICAL: Inavtivated Quadrivalent Influenza Virus Split Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety of and Immune Response to a Bird Flu Virus Vaccine (H9N2) in Healthy Adults (Study B)
Status: COMPLETED
Conditions: Influenza|Virus Diseases
Interventions: BIOLOGICAL: H9N2 (6-2) AA ca Reassortant (A/Chicken/Hong Kong/G9/97 x A/Ann Arbor/6/60 ca)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Volatile Anesthetics in Cardiac Protection
Status: RECRUITING
Conditions: Anesthesia
Interventions: DRUG: Sevoflurane (Volatile Anesthetic)|DRUG: Total intravenous anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Dulaglutide (LY2189265) in Participants With Type 2 Diabetes Mellitus in India
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Dulaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TPO-RA Treatment on Immune Tolerance Induction of ITP Patients With Sustained Platelet Recovery After Treatment Termination
Status: RECRUITING
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Hetrombopag Olamine|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluoroethyltyrosine for Evaluation of Intracranial Neoplasms
Status: COMPLETED
Conditions: Intracranial Neoplasm|Low Grade Glioma|Recurrent Glioblastoma|Recurrent World Health Organization (WHO) Grade II Glioma|Recurrent WHO Grade III Glioma
Interventions: DRUG: F-18 Fluoroethyltyrosine (FET)|PROCEDURE: Positron Emission Tomography (PET)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy
Status: TERMINATED
Conditions: Hypertrophic Cardiomyopathy
Interventions: DRUG: Eleclazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Flipped Learning on Nurses' Knowledge, Attitude, and Self-efficacy in Pressure Injury Prevention
Status: UNKNOWN
Conditions: Educational Problems
Interventions: OTHER: Micro-video digiral learning
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Lesion Progression After Icon Treatment in Young Adults
Status: TERMINATED
Conditions: Caries|Salivary Function|Tooth Sensitivity
Interventions: DEVICE: Resin infiltration|OTHER: Mock treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Post Marketing Surveillance Study to Assess the Safety and Efficacy of Cetuximab Plus Radiotherapy in Locally Advanced Squamous Cell Carcinoma of the Head and Neck
Status: TERMINATED
Conditions: Unresectable Locally Advanced Squamous Cell Carcinoma of Head and Neck|LA SCCHN
Interventions: DRUG: Cetuximab + RT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Alginate on Carbohydrate and Fat Digestion in a Mixed Meal
Status: COMPLETED
Conditions: Triacylglycerol Digestion
Interventions: DIETARY_SUPPLEMENT: Alginate Sausage|OTHER: Control Sausage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Topotecan Hydrochloride and Doxorubicin Hydrochloride in Treating Relapsed or Refractory Small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Small Cell Lung Carcinoma
Interventions: DRUG: Doxorubicin Hydrochloride|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|DRUG: Topotecan Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Relapsed/Recurrent/Refractory Pediatric Solid Tumors With Sorafenib in Combination With Irinotecan
Status: WITHDRAWN
Conditions: Pediatric Solid Tumors
Interventions: DRUG: Sorafenib|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing FARES Method With SPASO Method for Reduction of Anterior Shoulder Dislocation: a Prospective Randomized Trial
Status: UNKNOWN
Conditions: Shoulder Anterior Dislocation
Interventions: PROCEDURE: SPASO method and FARES method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Liraglutide Versus Placebo in Weight Loss Maintenance in Obese Subjects: SCALE - Maintenance
Status: COMPLETED
Conditions: Metabolism and Nutrition Disorder|Obesity
Interventions: DRUG: liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neurostimulation and OCD, a MRI Study
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: OTHER: Sham rTMS|OTHER: Active rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Sulfamethoxazole Drug Interaction Study With MMX® Mesalazine/Mesalamine
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: sulfamethoxazole + MMX placebo|DRUG: Sulfamethoxazole + MMX Mesalazine/mesalamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shift to Everolimus (RAD) Kidney Sparing Study
Status: TERMINATED
Conditions: Kidney Dysfunction|Heart Transplantation
Interventions: DRUG: cyclosporine|DRUG: cyclosporine|DRUG: Mycophenolate mofetil|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized Placebo Controlled Study to Determine Safety, Pharmacodynamics and Efficacy of ILV-094 in Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: ILV-094|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Tocilizumab in Patients With Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease
Status: RECRUITING
Conditions: Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease
Interventions: DRUG: Tocilizumab|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Safety and Efficacy of Risankizumab to Methotrexate in Subjects With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: risankizumab|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Palbociclib 125 mg Capsules of Iclos vs. Ibrance (Palbociclib) Capsules 125 mg
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Palbociclib 125mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Different Warming Methods in Laparoscopic Cholecystectomy Surgery
Status: COMPLETED
Conditions: Inadvertent Perioperative Hypothermia
Interventions: DEVICE: Forced Air Warming|DEVICE: Peripheral Carbon Fiber Warming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome
Status: COMPLETED
Conditions: Carcinoid Syndrome
Interventions: DRUG: Telotristat etiprate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II of Efficacy and Toxicity of Maintenance Sub. Rituximab After Induction in Relapsed MCL and Non-eligible HSCT
Status: UNKNOWN
Conditions: Mantle-cell Lymphoma
Interventions: DRUG: subcutaneous Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supporting Family Members With Severe Grief Reaction During the COVID-19 Pandemic
Status: UNKNOWN
Conditions: Bereavement|Severe Grief Reaction
Interventions: OTHER: Bereavement Virtual Support Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tailored Self-Management of Temporomandibular Disorders (TMD) Using Health Information Technology
Status: COMPLETED
Conditions: Temporomandibular Joint Dysfunction Syndrome
Interventions: BEHAVIORAL: PACT Experimental Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Imatinib in Patients With Mucosal or Acral/Lentiginous Melanoma
Status: COMPLETED
Conditions: Mucosal Melanoma|Acral/Lentiginous Melanoma|Chronically Sun Damaged Melanomas
Interventions: DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Gingival Recession Defects Using Platelet-Rich Fibrin With an Allogenic Dermal Matrix
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Tunneled coronally advanced flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Botensilimab and Balstilimab Optimization in Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Botensilimab|DRUG: Balstilimab|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: Fluorouracil|DRUG: Bevacizumab|DRUG: Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Multicenter Randomized Double Blind Placebo Controlled Study With Antibacterial Prophylaxis in Azacitidine Treated MDS Patients
Status: COMPLETED
Conditions: Prevention
Interventions: DRUG: Levofloxacin|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Female Genital Erosive Lichen Planus(GELP) With Hexaminolevulinate PDT
Status: COMPLETED
Conditions: Genital Lichen Planus
Interventions: DRUG: clobetasol propionate 0,05% ointment|DRUG: hexaminolevulinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Recombinant COVID-19 Trivalent Protein Vaccine （CHO Cell）LYB002V14 in Booster Vaccination
Status: NOT_YET_RECRUITING
Conditions: SARS-CoV-2|COVID-19 Vaccine
Interventions: BIOLOGICAL: 30μg dose of LYB002V14|BIOLOGICAL: 60μg dose of LYB002V14|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of a Sciatic Block (SNB) Combined With a Continuous Femoral Block (CFNB) on Pain Scores After Knee Arthroplasty
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: SNB plus CFNB|PROCEDURE: CFNB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical and Functional Outcomes of Rectourethral Fistulas Surgery With Gracilis Flap Interposition After Localized Prostatic Cancer Treatment.
Status: COMPLETED
Conditions: Rectourethral Fistula
Interventions: PROCEDURE: Gracilis flap interposition for rectouretral fistula management
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Bronchoprotective Effects of a Single Dose of N6022 in Patients With Mild Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Active|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of rTMS for Upper Extremity Motor Function Recovery in Ischemic Stroke Patients
Status: COMPLETED
Conditions: Stroke|Hemiplegia
Interventions: DEVICE: Low frequency rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Pressure Control of Nifedipine GITS 60mg Treatment in Chinese Hypertensive Subjects Uncontrolled on Starting-dose Mono-therapyo-therapy.
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Nifedipine (Adalat GITS, BAY1040)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of ASP1941 in Combination With Sulfonylurea in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DEVICE: ipragliflozin|DRUG: Placebo|DRUG: Sulfonylurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Large Doses of Methylprednisolone Combined With Gabapentin in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Arthroplasty Complications|Knee Osteoarthritis|Pain, Postoperative|Perioperative Complication
Interventions: DRUG: Gabapentin 300mg|DRUG: Methylprednisolone 125 mg|DRUG: Tablet|DRUG: Normal Saline 10 mL Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of Near and Intermediate Visual Outcomes With Monofocal Intraocular Lenses: The Mast Study
Status: UNKNOWN
Conditions: Patients Implanted With Monofocal Intraocular Lens
Interventions: DEVICE: Monofocal Intraocular Lenses
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Anesthetics Agents on Vascular Injury and Level of Syndecan-1 During Knee Surgery
Status: COMPLETED
Conditions: Ischemia
Interventions: DRUG: propofol group|DRUG: Desflurane group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Trial for Implementation of a MPA PK Monitoring Strategy
Status: COMPLETED
Conditions: Transplant, Kidney
Interventions: DRUG: Mycophenolate mofetil + Tacrolimus|DRUG: Mycophenolate mofetil + Cyclosporin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Versus Late Initiation of Feeding in Premature Growth Restricted Newborns With Absent or Reversed End Diastolic Flow On Umbilical Artery Doppler (AREDF)
Status: COMPLETED
Conditions: Prematurity of Fetus|Postnatal Growth Disorder
Interventions: OTHER: Early Feeding|OTHER: Late Feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975)
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma (ESCC)|Gastroesophageal Junction Carcinoma (GEJC)|Esophageal Adenocarcinoma (EAC)
Interventions: BIOLOGICAL: pembrolizumab|DRUG: placebo|DRUG: cisplatin|DRUG: 5-FU|RADIATION: radiotherapy|DRUG: leucovorin|DRUG: levoleucovorin|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Long Term Follow up of the Efficacy of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye Disease
Status: COMPLETED
Conditions: Long Term Follow up Dry Eye Disease
Interventions: DRUG: OC-01 Low Dose, 0.12 mg/mL|DRUG: OC-01 Mid Dose, 0.6 mg/mL|DRUG: OC-01 High Dose, 1.2 mg/mL|DRUG: Placebo (vehicle) nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Olaparib/Trabectedin vs. Doctor's Choice in Solid Tumors
Status: COMPLETED
Conditions: Cancers With DNA Repair-Deficiency
Interventions: DRUG: Olaparib|DRUG: Physician's choice|DRUG: Trabectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Evaluation of Docetaxel and Carboplatin Followed by Tumor Volume Directed Pelvic Irradiation
Status: TERMINATED
Conditions: Advanced Endometrial Adenocarcinoma, Stage III A, B, C
Interventions: DRUG: Docetaxel and Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use Behavior, Nicotine Uptake, and Subjective Effects Comparison of Tobacco and Menthol e-Liquids by ENDS Consumers
Status: COMPLETED
Conditions: Electronic Cigarette Use
Interventions: OTHER: RELX ENDS Tobacco Flavor 1|OTHER: RELX ENDS Tobacco Flavor 2|OTHER: RELX ENDS Menthol Flavor 1|OTHER: RELX ENDS Menthol Flavor 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Continuous Subacromial Bupivacaine
Status: COMPLETED
Conditions: Shoulder Arthroscopy
Interventions: DRUG: bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Peer Education Based on Assertiveness Skills on Dating Violence Attitudes and Internalized Misogyny
Status: NOT_YET_RECRUITING
Conditions: Dating Violence
Interventions: BEHAVIORAL: The peer trainer will be subjected to assertiveness training based on dating violence and internalized misogyny by the researcher for 2 hours a day for 5 days.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Timing of Re-evaluation After Steps I-II of Periodontal Therapy
Status: RECRUITING
Conditions: Periodontitis
Interventions: PROCEDURE: Repeated subgingival instrumentation|PROCEDURE: Supragingival scaling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of THN102 on Sleepiness in Narcoleptic Patients
Status: COMPLETED
Conditions: Narcolepsy
Interventions: DRUG: Active comparator: Modafinil + placebo|DRUG: THN102 300/3|DRUG: THN102 300/27
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AHEAD: European Feasibility Study of the Cardiovalve Transfemoral Mitral Valve System
Status: RECRUITING
Conditions: Mitral Regurgitation|Mitral Valve Disease
Interventions: DEVICE: Cardiovalve Transfemoral Mitral Valve
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Tranexamic Acid in the Total Knee Arthroplasty.
Status: COMPLETED
Conditions: Knee Osteoarthritis|Blood Loss|Blood Transfusion
Interventions: DRUG: Tranexamic Acid 100 MG/ML|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Membrane Oxygenation Effect in Prolonged Cardiopulmonary Resuscitation
Status: COMPLETED
Conditions: Cardiopulmonary Resuscitation|Cardiac Arrest|Ventricular Tachycardia|Ventricular Fibrillation
Interventions: PROCEDURE: Extracorporeal membrane oxygenation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Italian Registry of HIV-1 Infected Patients With Drug-RESistant Virus to Reverse Transcriptase Inhibitors, InteGrasE and Viral Protease.
Status: RECRUITING
Conditions: HIV-1-infection|Multi-Antiviral Resistance
Interventions: OTHER: REGISTER CREATION
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HOrmone Therapy Immediately After Histological Diagnosis of Breast Cancer
Status: UNKNOWN
Conditions: Hormone Dependent Neoplasms|Breast Cancer Female
Interventions: DRUG: Aromatase Inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy, Safety and Pharmacokinetics of Pamiparib (BGB-290) in Participants With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced High-grade Ovarian Cancer|Triple Negative Breast Cancer
Interventions: DRUG: Pamiparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Branched-chain Amino Acid Supplementation on Muscle Damage
Status: UNKNOWN
Conditions: Muscle Damage
Interventions: DIETARY_SUPPLEMENT: BCAA 200mg/kg/day|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: BCAA 400mg/kg/day|BEHAVIORAL: Muscle damaging exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Yoga vs. Education for Restless Legs Syndrome: a Feasibility Study
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: BEHAVIORAL: Yoga|BEHAVIORAL: Educational film
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Hemodynamic Monitoring in Liver Transplant With VEnaRt Cardiac Output Versus Swan-Ganz Catheter (VERO Study)
Status: COMPLETED
Conditions: Cardiac Output, Low|Liver Transplant; Complications
Interventions: DEVICE: VEnaRt Cardiac Output
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Comparison of RPDs Retained by Conical and Galvanoformed Double Crowns.
Status: UNKNOWN
Conditions: Denture, Partial, Removable|Dental Prosthesis Retention|Oral Health|Tooth Abrasion
Interventions: PROCEDURE: survival failure of more than 20 %
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AGN 201904 Versus Esomeprazole in the Prevention of Aspirin-induced Stomach or Upper Intestinal Damage in Healthy Volunteers
Status: COMPLETED
Conditions: Peptic Ulcer
Interventions: DRUG: AGN 201904|DRUG: esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: INVEST Feasibility - Minimally Invasive Endoscopic Surgery With Apollo in Patients With Brain Hemorrhage
Status: COMPLETED
Conditions: Intracranial Hemorrhage
Interventions: DEVICE: Apollo MIES|OTHER: Medical Management
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Multidisciplinary Intensive Targeted Care in Improving Diabetes Outcomes: a Pilot Study in Singapore
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Diabetic Nephropathy|Hypertension
Interventions: BEHAVIORAL: Intensive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of SPD422 on Platelet Lowering and Safety in Japanese Adults With At Risk Essential Thrombocythaemia
Status: COMPLETED
Conditions: Essential Thrombocythemia (ET)
Interventions: DRUG: Anagrelide Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Differences in Timely Cancer Diagnosis in African American and Caucasian Patients With Newly Diagnosed Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: OTHER: medical chart review|OTHER: questionnaire administration|OTHER: study of socioeconomic and demographic variables|OTHER: survey administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vaccine Therapy and Sargramostim Compared With Placebo and Sargramostim Following Rituximab in Treating Patients With Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: BIOLOGICAL: autologous immunoglobulin idiotype-KLH conjugate vaccine|BIOLOGICAL: rituximab|BIOLOGICAL: sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Zileuton With or Without Celecoxib As Chemopreventive Agents in Smokers
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: DRUG: Zileuton|DRUG: Celecoxib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Ponatinib (Iclusig) for Prevention of Relapse After Allogeneic Stem Cell Transplantation (Allo-SCT) in FLT3-ITD AML Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Ponatinib 30 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Evaluation of a Digital Peer Support Intervention for Suicidal Adolescents
Status: NOT_YET_RECRUITING
Conditions: Suicide
Interventions: BEHAVIORAL: Supporting Wellbeing with Everyday Experiences of Peers (SWEEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Acute Haemodynamic Study of TPN171H in Patients With Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: TPN171H|DRUG: Placebo|DRUG: Tadalafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of tDCS on Sport Performance for Two Categories of Athletes : Explosive Profile and Enduring Profile
Status: UNKNOWN
Conditions: Healthy Volunteers|High-level Sportsman
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS|DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Adolescent PCIP Randomized Feasibility Trial
Status: SUSPENDED
Conditions: Post-Traumatic Stress Disorder in Adolescence|Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: Primary Care Intervention for PTSD (PCIP)|BEHAVIORAL: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The SpACE Study - Small Bowel Crohn's Disease and Spondyloarthropathies
Status: COMPLETED
Conditions: Spondyloarthropathy|Crohn Disease
Interventions: DEVICE: Videocapsule endoscopy|PROCEDURE: colonoscopy|DIAGNOSTIC_TEST: PROMETHEUS® IBD sgi Diagnostic™|DIAGNOSTIC_TEST: Fecal calprotectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: NG-Nitro-L-Arginine in Treating Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: NG-nitro-L-arginine|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: computed tomography|PROCEDURE: dynamic contrast-enhanced magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Physiotherapy or Fasciotomy as Treatment for Chronic Exertional Compartment Syndrome in the Lower Leg?
Status: RECRUITING
Conditions: Compartment Syndrome Nontraumatic Lower Leg
Interventions: PROCEDURE: Surgery/Fasciotomy|OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GECo: Implementation and Effectiveness of COPD Self Management Action Plans in Low and Middle Income Countries
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: COPD Self-Management Plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Controlled Trial of Omadacycline Randomized Treatment Given for Bone and Joint Infection
Status: RECRUITING
Conditions: Bone Infection|Joint Infection|Bone and Joint Infection
Interventions: DRUG: Omadacycline Pill|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-centric Study to Assess the Efficacy of Sigmart in Subjects With Recurrent Angina After Coronary Revascularization
Status: WITHDRAWN
Conditions: Angina Pectoris
Interventions: DRUG: Sigmart (nicorandil)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of 10 Repetitions of Deep Breathing Exercises
Status: COMPLETED
Conditions: Heart; Surgery, Heart, Functional Disturbance as Result
Interventions: OTHER: 10 Repetitions of Deep Breathing Exercise|OTHER: 3 Repetitions of Deep Breathing Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabotropic Glutamate Receptor-5 (mGlur5) Effects on Reward-Related fMRI-BOLD Activation in FHP and FHN
Status: COMPLETED
Conditions: Familial Alcoholism Vulnerability
Interventions: DRUG: Mavoglurant (AFQ056)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PRESERVE-Zenith® Iliac Branch System Clinical Study
Status: COMPLETED
Conditions: Aorto-iliac Aneurysms|Iliac Aneurysms
Interventions: DEVICE: Endovascular repair for aortoiliac or iliac aneurysms.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: T-cell Depleted Donor Lymphocyte Infusion (DLI)for Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome (MDS)
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: PROCEDURE: CD8+ T-cell depleted donor lymphocyte infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Spearmint Tea in Relieving Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: OTHER: Commercially spearmint tea|OTHER: High Rosmarinic Acid Spearmint Tea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Understanding the Effects of Intervention on the Brain in Autism
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder|Asperger Disorder|PDD-NOS|Autism
Interventions: BEHAVIORAL: PEERS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glucose Response From Antioxidant Rich Potato Chips
Status: COMPLETED
Conditions: Glycemic Response
Interventions: OTHER: Purple Majesty potato chips|OTHER: Mountain Rose potato chips|OTHER: White potato chips|OTHER: Crackers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Changes in Fluid Status on Right Ventricular Volumes and Function
Status: COMPLETED
Conditions: Tetralogy of Fallot
Interventions: PROCEDURE: Cardiac Magnetic Resonance Imaging (CMRI)|PROCEDURE: Central venous line placement|PROCEDURE: Chest X-ray|PROCEDURE: Fluid administration|PROCEDURE: Blood Draw|PROCEDURE: Pregnancy test|PROCEDURE: Electrocardiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pragmatic Randomized Trial for Arterial Catheters in the Critical Care Environment
Status: COMPLETED
Conditions: Mechanical Ventilation Complication|Arterial Thrombosis|Limb Ischemia|Shock|Hypotension|Bloodstream Infection|Vasopressor Adverse Reaction|Renal Failure
Interventions: OTHER: Restricted-use of arterial catheter|OTHER: Standard-use of arterial catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Anaesthesia for Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Obese
Interventions: DRUG: Propofol|DRUG: Remifentanil|DRUG: Dexmedetomidine|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Addressing Substance Use Through CVCT
Status: COMPLETED
Conditions: Sex, Unsafe|Drug Use
Interventions: BEHAVIORAL: Communication skills training video|BEHAVIORAL: substance use module|BEHAVIORAL: Couples HIV Testing and Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION