pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Platelet-rich Fibrin With 1.2% Rosuvastatin in Chronic Periodontitis Treatment
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: PROCEDURE: Open flap debridement (OFD)|PROCEDURE: OFD with Platelet rich fibrin (PRF)|PROCEDURE: OFD with PRF and 1.2% Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Erector Spinae Block vs Thoracolumbar Interfascial Plane Block
Status: NOT_YET_RECRUITING
Conditions: Analgesia|Lumbar Spine Disease
Interventions: DRUG: Propofol|DRUG: Fentanyl|DRUG: Rocuronium|DRUG: Sevoflurane|OTHER: Erector spinae plane block|OTHER: Thoracolumbar interfascial plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Combination Antiretroviral Therapy (cART) for PBC
Status: COMPLETED
Conditions: Primary Biliary Cholangitis
Interventions: DRUG: Emtricitabine (FTC)/Tenofovir Disoproxil (TDF)|DRUG: Raltegravir|DRUG: Placebo Oral Capsule [CEBOCAP]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Residual Dental Pulp Tissue and Cord Blood Stem Cells
Status: WITHDRAWN
Conditions: Irreversible Pulpitis
Interventions: BIOLOGICAL: Cord blood stem cells|OTHER: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Two-Stage Study of the Efficacy, Safety, Pharmacokinetics, Pharmacodynamics and Immunogenicity of Various Doses of Levilimab When Administered Intravenously and Subcutaneously to Healthy Subjects and Subjects With Active Rheumatoid Arthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Levilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Evaluation of HIV-associated Lung Disease Phenotypes
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|HIV|Emphysema
Interventions: PROCEDURE: blood draw|PROCEDURE: questionnaires|PROCEDURE: Lung function testing|PROCEDURE: Six-Minute walk test|RADIATION: Quantitative CT scans|PROCEDURE: Nasal secretion and cell collection|PROCEDURE: Echocardiogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Different Interventions on Glycemic Control and β-cell Function in Newly Diagnosed Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Newly Diagnosed
Interventions: DRUG: exenatide injection|DRUG: Mixed Protamine Zinc Recombinant Human Insulin Lispro 25R|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention
Status: RECRUITING
Conditions: BRCA1 Gene Mutation|BRCA2 Gene Mutation|RAD51C Gene Mutation|RAD51D Gene Mutation|BRIP1 Gene Mutation|Ovarian Cancer
Interventions: PROCEDURE: Risk-reducing salpingectomy with delayed oophorectomy|PROCEDURE: Risk-reducing salpingo-oophorectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: DBPC-Dose-finding-trial of Vitamin D3 for SCIT in Birch Pollen Allergic Patients.
Status: COMPLETED
Conditions: Hypersensitivity
Interventions: DRUG: Paricalcitol|DRUG: Placebo (for paricalcitol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: MTT for Children With Both Pitt Hopkins Syndrome and Gastrointestinal Disorders
Status: COMPLETED
Conditions: Pitt Hopkins Syndrome
Interventions: COMBINATION_PRODUCT: vancomycin, magnesium citrate, microbiota|COMBINATION_PRODUCT: placebo vancomycin, real magnesium citrate, placebo microbiota
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects on Maxillary Anterior Dentition Following En Masse Retraction Using Mini-implants and Various Heights of Anterior Power Arm.
Status: COMPLETED
Conditions: Varying Heights of Power Arm During en Masse Retraction
Interventions: OTHER: Anterior Power Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repurposing of Dextromethorphan as an Adjunct Therapy in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Selective Serotonin Reuptake Inhibitors|DRUG: Dextromethorphan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Rituximab in Lymphoid Malignancies Involving Central Nervous System
Status: TERMINATED
Conditions: Leukemia|Lymphoid Malignancies|Metastatic Malignant Neoplasm to the Leptomeninges
Interventions: DRUG: Intrathecal Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of CHS-1420 Versus Humira in Subjects With Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: CHS-1420|DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relaxation Exercises for Low Back Pain and Insomnia in the Third Trimester of Pregnancy
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Conventional Physical Therapy|OTHER: Relaxation exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Systematic Referral to Palliative Care of Patients Who Need for Palliative Care During an Unscheduled Visit in Comprehensive Anticancer Centers
Status: NOT_YET_RECRUITING
Conditions: Cancer|Emergencies
Interventions: OTHER: Systematic referral to a palliative care team
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Feasibility Study of Normobaric Oxygen Delivered by a High Flow Concentrator in the Treatment of Chronic Headache
Status: UNKNOWN
Conditions: Chronic Headache
Interventions: DEVICE: platinium IRC9LXO2AWQ
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OPtical Frequency Domain Imaging vs. INtravascular Ultrasound in Percutaneous Coronary InterventiON
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: OFDI|DEVICE: IVUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: N-methyl Glycine (Sarcosine) for the Treatment of Obsessive Compulsive Disorder (OCD)
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: DRUG: N-methyl glycine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Post-Marketing Observational Safety Study of Verzenios® (Abemaciclib) Among Breast Cancer Patients in China Verzenios® (Abemaciclib) Among Breast
Status: NOT_YET_RECRUITING
Conditions: The Incidence of AEs and SAEs Receiving Verzenios® Over a Period of Approximately 24 Weeks
Interventions: OTHER: Verzenios
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Demonstrate the Relative Bioavailability of Cetirizine Hydrochloride/Pseudoephedrine Hydrochloride 5 mg/120 mg Extended Release (ER) Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Allergies
Interventions: DRUG: Cetirizine HCl/Pseudoephedrine HCl 5 mg/120 mg (Sandoz, USA)|DRUG: Zyrtec-D 12 Hour 5 mg/120 mg Extended Release Tablets (Pfizer, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Strategy vs Palpation vs Routine Ultrasound for Detection of Cricothyroid Membrane
Status: UNKNOWN
Conditions: Airway Disease|Intubation; Difficult or Failed|Ultrasound Therapy
Interventions: DIAGNOSTIC_TEST: Palpation with " laryngeal handshake" technique|DIAGNOSTIC_TEST: Palpation strategy plus sequential ultrasound|DIAGNOSTIC_TEST: Identification of the cricothyroid membrane with routine ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Imatinib Mesylate in Treating Patients With Recurrent Brain Tumor
Status: COMPLETED
Conditions: Adult Anaplastic Oligodendroglioma|Adult Mixed Glioma|Adult Oligodendroglioma|Recurrent Adult Brain Neoplasm
Interventions: DRUG: Imatinib Mesylate|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety of and Immune Response to an HIV Vaccine Followed by Booster, Administered by Two Devices, in HIV-Uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: PENNVAX-G DNA Vaccine|BIOLOGICAL: MVA-CMDR Vaccine|BIOLOGICAL: Placebo PENNVAX-G Vaccine|BIOLOGICAL: Placebo MVA-CMDR Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Role of Vitamin D Therapy in Recovery From Early Neonatal Sepsis (Randomized Controlled Trial)
Status: COMPLETED
Conditions: Importance of Vitamin D Therapy in Treatment of Neonatal Sepsis
Interventions: DRUG: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: HYPAR Trial - Hydrocortisone vs. Pasireotide in Reducing Pancreatic Surgery Complications
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Fistula|Pancreatic Neoplasms
Interventions: DRUG: Hydrocortisone|DRUG: Pasireotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: A Phase 1 Study to Evaluate the Safety/Tolerability, PK/PD of RG002C0106 Injection in Healthy Adults
Status: NOT_YET_RECRUITING
Conditions: Safety Issues
Interventions: DRUG: RG002C0106
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of NVA237 (50 μg o.d) Using Tiotropium (5μg μg o.d) as Active Control in COPD Patients.
Status: WITHDRAWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: NVA237|DRUG: Tiotropium Respimat®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pretreatment Sarcopenia in Patients With Inoperable High-grade Ovarian Carcinoma as Part of Optimised Management
Status: RECRUITING
Conditions: Ovarian Carcinoma
Interventions: OTHER: Presence of sarcopenia evaluated prior to neoadjuvant chemotherapy and during chemotherapy as part of optimised management(dietician and APA).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hypofractionated Whole Pelvic Radiotherapy of the Prostate
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: RADIATION: Helical TomoTherapy (HT)|RADIATION: CyberKnife SBRT|RADIATION: Permanent Prostate Implant (PPI)|RADIATION: HDR brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Fish Oil on Plasma Triglycerides in Adults
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DIETARY_SUPPLEMENT: Fish oil (90% triglycerides)|DIETARY_SUPPLEMENT: Fish oil (60% triglycerides)|DIETARY_SUPPLEMENT: Fish oil (ethyl esters)|DIETARY_SUPPLEMENT: Soy oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Wharton´s Jelly Derived Mesenchymal Stromal Cell Repeated Treatment of Adult Patients Diagnosed With Type I Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type1diabetes
Interventions: DRUG: ProTrans|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Change in Patient-repOrted Outcomes in COPD Patients Newly Initiated on TRIXEO AEROSPHERE in Real worlD
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: budesonide / glycopyrronium / formoterol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: STI-6129 CD38 ADC for the Treatment of Patients With Relapsed or Refractory Systemic ALL Amyloidosis
Status: WITHDRAWN
Conditions: Refractory T Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia (AML)
Interventions: DRUG: Part 1 (STI-6129)|DRUG: Part 2 (STI-6129)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blinatumomab in Adults With Relapsed/Refractory Philadelphia Positive B-precursor Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Relapsed/Refractory Philadelphia Positive B-precursor ALL
Interventions: DRUG: Blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Montelukast Versus Intranasal Fluticasone Propionate in the Management of Allergic Rhinitis Among Children 02 to 05 Years of Age
Status: UNKNOWN
Conditions: Allergic Rhinitis
Interventions: DRUG: Effectiveness of Montelukast Versus Intranasal Fluticasone Propionate in the Management of Allergic Rhinitis Among Children 02 to 05 Years of Age
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion
Status: COMPLETED
Conditions: Inappropriate ADH Syndrome|Hyponatremia
Interventions: DRUG: SR121463B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nonmyeloablative Stem Cell Transplantation With CD8-depleted or Unmanipulated Peripheral Blood Stem Cells (PBSC)
Status: COMPLETED
Conditions: Hematologic Malignancies
Interventions: PROCEDURE: Unmanipulated PBSC after nonmyeloablative conditioning|PROCEDURE: CD8-depleted PBSC after nonmyeloablative conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of Roxadustat Versus Recombinant Human Erythropoietin (rHuEPO) on Oral Iron Absorption in Chinese Patients With Anemia of Chronic Kidney Disease (CKD)
Status: COMPLETED
Conditions: Anemia of Chronic Kidney Disease
Interventions: DRUG: Roxadustat|DRUG: rHuEPO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibody Titer Analysis After H1N1 Vaccination in Pediatric Haemato-oncology Patients
Status: UNKNOWN
Conditions: Serology Analysis|Novel H1N1 Influenza Vaccination|Pediatric Haemato-oncology Patients
Interventions: BIOLOGICAL: Influenza A (H1N1) 2009 monovalent vaccine, inactivated
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety Study of Dietary Supplements in Chronic Smokers Having Mild to Moderate Hyperlipidemia
Status: UNKNOWN
Conditions: Chronic Smokers|Hyperlipidemia
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: BioTurmin (Curcuma longa rhizomes extract)|DIETARY_SUPPLEMENT: BioTurmin-WD (Water dispersible curcuminoids)|DIETARY_SUPPLEMENT: MaQxan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of AK104/Tislelizumab With Chemotherapy as First-line Treatment in PD-L1 TPS < 1% Non-small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced or Metastatic NSCLC
Interventions: DRUG: AK104|DRUG: Tislelizumab|DRUG: carboplatin|DRUG: Pemetrexed|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Effects of Adderall in Healthy Adults.
Status: COMPLETED
Conditions: Hemodynamics|Cardiovascular System
Interventions: DRUG: Adderall capsule|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Treatment of Acute Lymphoblastic Leukemia Ph '(BCR / ABL) Positive Patients Aged > 55 Years
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia Ph Positive
Interventions: DRUG: Dexamethasone|DRUG: Methotrexate|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison The Postoperative Effects of Local and Systemic Antibiotics Applied With Platelets Rich Fibrin
Status: COMPLETED
Conditions: Impacted Wisdom Tooth
Interventions: DIAGNOSTIC_TEST: Diagnosis|PROCEDURE: traditional osteotomies|BIOLOGICAL: Platelet Rich Fibrin|DRUG: Antibiotics, Penicillin|DRUG: Analgesic|DRUG: Antibiotic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Measurement of Resistance During UAS Insertion Procedure in RIRS
Status: UNKNOWN
Conditions: Urolithiasis
Interventions: PROCEDURE: empty bladder before inserting UAS|PROCEDURE: do not interfere with the filling degree of bladder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EUS-guided Celiac Plexus Neurolysis for the Treatment of Abdominal Pain in Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: PROCEDURE: EUS-guided celiac plexus neurolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Adrenal Suppression Potential and PK of CB-03-01 Cream in Pediatric Patients With Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: cortexolone 17α-propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Refractory ANCA Associated Vasculitis and Lupus Nephritis Treated With BCMA-targeting CAR-T Cells
Status: RECRUITING
Conditions: Lupus Nephritis|ANCA Associated Vasculitis
Interventions: DRUG: PRG-1801 （CAR-T against BCMA）
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Alfacalcidol on Muscle Function in Osteoporosis Patients
Status: NOT_YET_RECRUITING
Conditions: Sarcopenia
Interventions: DRUG: alfacalcidol|DRUG: placebo|DRUG: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erenumab for Idiosyncratic Facial Pain
Status: COMPLETED
Conditions: Facial Pain|Rhinosinusitis
Interventions: DRUG: Erenumab Prefilled Syringe|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dry Eye Disease Study With Brimonidine
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Brimonidine|DRUG: Brimonidine Mono Therapy|DRUG: sodium carboxymethylcellulose|DRUG: Corticosteroid Eye Drop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carotid Artery Revascularization Using the Boston Scientific EPI Filter Wire EZ™ and the EndoTex™ NexStent™
Status: COMPLETED
Conditions: Transient Ischemic Attack|Thromboembolic Stroke|Stroke Prevention
Interventions: DEVICE: EndoTex™ NexStent™|DEVICE: Filter Wire EZ™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Trabectedin to the Best Supportive Care in Patients With Sarcoma
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Trabectedin|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Birth Outcomes of Swedish, Danish and Finnish Women Exposed to Remicade With Inflammatory Bowel Disease, Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, and Psoriasis
Status: COMPLETED
Conditions: Inflammatory Bowel Disease
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TNF and Glucocorticoid Antagonist for GWI Associated Multi-symptom Disease Homeostasis Reset
Status: RECRUITING
Conditions: Gulf War Illness
Interventions: DRUG: Etanercept|DRUG: Mifepristone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of a Tacrolimus Hexal® Based Regimen Versus a Prograf® Based Regimen in de Novo Renal Transplant Recipients
Status: COMPLETED
Conditions: Pharmacokinetics Study in de Novo Kidney Transplantation
Interventions: DRUG: Prograf|DRUG: Tacrolimus Hexal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Strategies for Improving Proton Pump Inhibitors (PPIs) Prescription Associated to Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Status: WITHDRAWN
Conditions: Adverse Events
Interventions: BEHAVIORAL: Group education, audit-feedback and computer support|BEHAVIORAL: Audit-feedback and computer support|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: EUS-guided Versus Percutaneous Ultrasound-guided Biopsy for Parenchymal Liver Disease
Status: NOT_YET_RECRUITING
Conditions: Liver Cirrhosis
Interventions: DIAGNOSTIC_TEST: EUS guided liver biopsy|DIAGNOSTIC_TEST: Percutaneous Liver Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Checklist to Prevent MRSA Surgical Site Infections
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: DRUG: Mupirocin|DRUG: Chlorhexidine gluconate|DRUG: Cefazolin|DRUG: Vancomycin|DRUG: Nasal Povidone Iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Probiotic Treatment in Juvenile Idiopathic Arthritis (JIA)
Status: UNKNOWN
Conditions: Juvenile Idiopathic Arthritis
Interventions: DIETARY_SUPPLEMENT: VSL#3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CPX-351+GO in Subjects 55 Years Old, or Older, With AML
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: CPX-351|DRUG: Gemtuzumab Ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Trial for Psychogenic Nonepileptic Seizures
Status: COMPLETED
Conditions: Convulsion, Non-Epileptic|Conversion Disorder|Depression|Stress Disorders, Post-Traumatic|Dissociative Disorders
Interventions: DRUG: sertraline|BEHAVIORAL: CBT-ip|OTHER: Combined (sertraline + CBT-ip)|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and Pharmacokinetics of NNC-0156-0000-0009 in Previously Treated Children With Haemophilia B.
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia B
Interventions: DRUG: nonacog beta pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TMC114-C201: A Study to Determine the Antiviral Activity of TMC114 in Patients With Multiple Protease Inhibitor (PI) Resistant Human Immunodeficiency Virus (HIV) Strains
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: TMC114
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CRT Hydration in the Last Days of Life (Feasibility Study)
Status: COMPLETED
Conditions: Cancer
Interventions: OTHER: Non-Clinically Assisted Hydration arm|OTHER: Clinically Assisted Hydration arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Bimekizumab in Patients With Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis
Interventions: DRUG: Bimekizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carbon Dioxide Versus Air Insufflation for the Application of Argon Plasma to Reduce the Gastrojejunal Anastomosis
Status: COMPLETED
Conditions: Dilatation of Anastomosis|Bypass Complication|Obesity
Interventions: DRUG: Carbon dioxide|DRUG: Ambient air|DRUG: Argon fulguration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Effectiveness, and Pharmacokinetic Data in Opioid-experienced Children
Status: SUSPENDED
Conditions: Chronic Pain|Postsurgical Pain
Interventions: DRUG: Oxymorphone hydrochloride (HCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Clinical Trial of MG-ZG122 in Chinese Healthy Adult Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma
Interventions: DRUG: MG-ZG122 Humanized Monoclonal Antibody Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of BEBT-908 Combined With Drugs in the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Status: RECRUITING
Conditions: Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Interventions: DRUG: BEBT-908 for Injection|DRUG: Rituximab Injection|DRUG: Gemcitabine Hydrochloride for Injection|DRUG: Oxaliplatin Injection|DRUG: Etoposide Injection|DRUG: Ifosfamide for Injection|DRUG: Carboplatin Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of NN5401 Plus Insulin Aspart With Insulin Detemir Plus Insulin Aspart in Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec/insulin aspart|DRUG: insulin detemir|DRUG: insulin aspart|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Budesonide/Formoterol Turbuhaler® Versus Terbutaline Nebulization as Reliever Therapy in Children With Moderate Asthma Exacerbation
Status: TERMINATED
Conditions: Asthma in Children
Interventions: DRUG: Budesonide Formoterol Drug Combination|DRUG: nebulisation of terbutaline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Impact of DPD Activity on the Efficacy of Capecitabine
Status: RECRUITING
Conditions: Breast Neoplasm Malignant Female
Interventions: OTHER: DPD activity assessment|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Plazomicin Compared With Meropenem for the Treatment of Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis (AP)
Status: COMPLETED
Conditions: Complicated Urinary Tract Infection|Acute Pyelonephritis
Interventions: DRUG: plazomicin|DRUG: meropenem|DRUG: levofloxacin (oral)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Shotblocker on Procedure-related Pain, Satisfaction and Comfort in Patients Receiving Spinal Anesthesia
Status: NOT_YET_RECRUITING
Conditions: Pain
Interventions: DEVICE: Shotblocker|OTHER: Shotblocker(Plasebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Panzyga in CIDP Administered at Different Infusion Rates
Status: UNKNOWN
Conditions: Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Interventions: DRUG: Immune Globulin 10% Intravenous Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Stimulation And Group Therapy to Improve Gesture and Social Skills in Psychosis (BrAGG-SoS)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DEVICE: continuous theta burst stimulation (cTBS)|DEVICE: placebo cTBS|BEHAVIORAL: social cognitive remediation therapy (SCRT)|BEHAVIORAL: Sham group therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Administration of Tannins and Flavonoids in Children With Acute Diarrhea
Status: COMPLETED
Conditions: Acute Diarrhea
Interventions: DRUG: Actitan F|DRUG: Standard Oral Rehydration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Soft Tissue Biopsy System for Trans-rectal and Trans-perineal Biopsy of the Prostate
Status: UNKNOWN
Conditions: Prostate Disease
Interventions: DEVICE: Prostate biopsy needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Telehealth on Engagement in Psychotherapy and/or Medication Treatment
Status: TERMINATED
Conditions: Psychiatric Diagnosis
Interventions: BEHAVIORAL: Making Connections Intervention-Telehealth (MCI-T)|BEHAVIORAL: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Effectiveness of Audio Guided Deep Breathing on Improving the Quality of Life of Physically Disabled Group
Status: UNKNOWN
Conditions: Psychophysiology|Visually Impaired Persons|Physiological Phenomena|Psychological Stress
Interventions: OTHER: Audio-guided deep breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hyperpolarized 13C Pyruvate MRI for Treatment Response Assessment in Pancreatic Ductal Adenocarcinoma
Status: TERMINATED
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Hyperpolarized Carbon C 13 Pyruvate|PROCEDURE: Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Analytical Study of Intravenous Bolus Dose of Mephentermine and Phenylephrine for Hemodynamic Stability During Elective Cesarean Section Under Spinal Anesthesia at KIST Medical College and Teaching Hospital
Status: RECRUITING
Conditions: Hemodynamic Stability
Interventions: DRUG: Intravenous bolus dose of Mephentermine and mephentermine|DRUG: intravenous bolus dose of phenylephrine 50 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Cooperative Clinical Study of Abatacept in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: BIOLOGICAL: abatacept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ibuprofen on Postoperative Opiate Medication Use and Shoulder
Status: UNKNOWN
Conditions: Rotator Cuff Tear Arthropathy
Interventions: DRUG: Ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oxytocin on Fear Memory Consolidation Novel Intervention to Prevent Posttraumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Efficacy of Disulfiram in LAAM-Maintained Cocaine Abusers
Status: COMPLETED
Conditions: Cocaine-Related Disorder|Opiate Dependence
Interventions: DRUG: Placebo|DRUG: Disulfiram|DRUG: Disulfiram|DRUG: Disulfiram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multivirus-specific T Cells in the Treatment of Refractory CMV and/or EBV Infection After Allo-HSCT
Status: NOT_YET_RECRUITING
Conditions: CMV Infection|EBV Infection|Stem Cell Transplant
Interventions: BIOLOGICAL: Virus specific T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid Versus Placebo for the Reduction of Blood Loss in Total Hip Replacement Surgery
Status: COMPLETED
Conditions: Hip Replacement, Total
Interventions: DRUG: A|DRUG: B|DRUG: C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: 3D-printed Endocrowns Versus Prefabricated Zirconia Crowns in Pulpally-treated Primary Molars
Status: COMPLETED
Conditions: Pulpotomy|Tooth Restoration
Interventions: PROCEDURE: 3D-printed endocrown|PROCEDURE: Zirconia crown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INVESTIGATE THE ASSOCIATION BETWEEN VIRAL NEUROTOXIC INFECTION AND POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
Status: NOT_YET_RECRUITING
Conditions: POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
Interventions: DIAGNOSTIC_TEST: Virological screening
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Autologous Adult Stem Cells to Patients With Type 1 Diabetes and a Successful Renal Transplant
Status: COMPLETED
Conditions: Type 1 Diabetes|Type 2 Diabetes
Interventions: BIOLOGICAL: Autologous CD34+ stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine and Ivermectin for the Treatment of COVID-19 Infection
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Hydroxychloroquine|DRUG: Ivermectin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: PRP for Glenohumeral Osteoarthritis
Status: RECRUITING
Conditions: Shoulder Osteoarthritis
Interventions: BIOLOGICAL: Low-dose PRP|BIOLOGICAL: High-dose PRP|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Imatinib Treatment After 10 Years of Treatment in Patients With Gastrointestinal Stromal Tumours (GIST) (Gist-Ten)
Status: RECRUITING
Conditions: Metastatic Gastrointestinal Stromal Tumor (GIST)|C-KIT Mutation|Advanced Gastrointestinal Stromal Tumor (GIST)
Interventions: DRUG: Imatinib tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Return to Work After Hand Injury: the Role of Medical, Demographic and Psycho-Social Factors
Status: UNKNOWN
Conditions: Hand Injury
Interventions: BEHAVIORAL: Questionnaires and motor/sensitivity testing|BEHAVIORAL: Questionnaires and motor/sensitivity testing|BEHAVIORAL: Questionnaires and motor/sensitivity testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antithrombotic Therapy With Regulation of Blood Pressure in Non-Cardioembolic Progressive Stroke
Status: ENROLLING_BY_INVITATION
Conditions: Stroke, Ischemic
Interventions: OTHER: Intervention group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multifidus Activation, Pain and Functional Disability in Individuals With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: PROCEDURE: Lumbar Stabilisation Exercise|PROCEDURE: treadmill walk exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telemedicine Nurse-Led Intervention for Rural Cancer Survivors
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Neoplasm|Survivorship
Interventions: BEHAVIORAL: Comprehensive Assistance: Rural Interventions, Nursing, and Guidance (CARING)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of mRNA-3745 in Adult and Pediatric Participants With Glycogen Storage Disease Type 1a (GSD1a)
Status: RECRUITING
Conditions: Glycogen Storage Disease
Interventions: DRUG: mRNA-3745
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Midostaurin and Decitabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia and FLT3 Mutation
Status: TERMINATED
Conditions: Acute Myeloid Leukemia With FLT3/ITD Mutation|Acute Myeloid Leukemia With Gene Mutations|FLT3 Tyrosine Kinase Domain Point Mutation|Secondary Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: Decitabine|OTHER: Laboratory Biomarker Analysis|DRUG: Midostaurin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real-World AR101 Market-Supporting Experience Study in Peanut-Allergic Children (RAMSES)
Status: COMPLETED
Conditions: Peanut Allergy
Interventions: BIOLOGICAL: AR101|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does Isolated Robotic-Assisted Gait Training Improve Functional Status, Daily Living And Quality Of Life In Stroke?
Status: COMPLETED
Conditions: Cerebrovascular Stroke|Cerebrovascular Accident|Cerebral Stroke
Interventions: OTHER: Robotic-Assisted Gait Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing "SupporT for ADHD and Related Treatment" (START) for Families of Children With ADHD
Status: RECRUITING
Conditions: ADHD
Interventions: BEHAVIORAL: SupporT for ADHD and Related Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Esomeprazole for Relief of Upper Gastrointestinal Symptoms Associated With Continuous Use of NSAIDs
Status: COMPLETED
Conditions: NSAIDs|Upper GI Symptoms
Interventions: DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: SGLT2 Inhibitors As First Line Therapy to Prevent Renal Decline in Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: Dapagliflozin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Palbociclib (PD-0332991) + Letrozole vs. Letrozole For 1st Line Treatment Of Postmenopausal Women With ER+/HER2- Advanced Breast Cancer (PALOMA-2)
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: PD-0332991|DRUG: Letrozole|DRUG: Placebo|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A PHASE 1, OPEN-LABEL, CROSS-OVER, FIXED SEQUENCE STUDY TO EVALUATE THE EFFECT OF MULTIPLE DOSES OF DS-1971A ON THE SINGLE DOSE PHARMACOKINETICS OF PROBE SUBSTRATES FOR CYP2B6, CYP2C8, CYP2C9, CYP2C19 AND CYP3A4 ENZYMES IN HEALTHY MALE AND FEMALE SUBJECTS
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DS-1971a|DRUG: midazolam hydrochloride|DRUG: Omeprazole|DRUG: Pioglitazone hydrochloride|DRUG: Buproprion|DRUG: Tolbutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pre-phase Treatment Before R-CHOP Chemotherapy in Elderly Patients With Newly Diagnosed DLBCL
Status: COMPLETED
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: PrednisoLONE 50 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Implantation of a Trifocal Hydrophobic IOL in Patients That Underwent Refractive Surgery
Status: WITHDRAWN
Conditions: Cataract|Lens Opacities|Presbyopia
Interventions: DEVICE: IOL implantation experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Voice Therapy Per the Rehabilitation Treatment Specification System
Status: NOT_YET_RECRUITING
Conditions: Muscle Tension Dysphonia
Interventions: BEHAVIORAL: Standard of care voice therapy with novice clinician RTSS-Voice documentation|BEHAVIORAL: Standard of care voice therapy with expert clinician RTSS-Voice documentation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase II Study of SSGJ-707 Monotherapy in First-line PD-L1 Positive Advanced NSCLC Patients
Status: RECRUITING
Conditions: NSCLC
Interventions: DRUG: SSGJ-707
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Silver Diamine Fluoride and Papain-Based Gel for Management of MIH-affected Molar in Paediatric Patients
Status: COMPLETED
Conditions: Molar Incisor Hypomineralization|Dental Caries|Hypomineralization of Enamel
Interventions: DEVICE: Silver Diamine Fluoride|DEVICE: Papain-Based Gel|DEVICE: High Viscosity Glass Ionomer Cement (HVGIC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The CAROLE (CArdiac Related Oncologic Late Effects) Study
Status: COMPLETED
Conditions: Coronary Artery Disease|Cardiac Disease|Cardiac Toxicity|Radiation|Radiation Therapy|Atherosclerotic Heart Disease|Cardiotoxicity|Breast Cancer|Lung Cancer|Lymphoma|Cancer|Carcinoma, Intraductal, Noninfiltrating
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I/IIA Study of PET Imaging With 89Zr-Df-IAB2M in Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Prostate Cancer
Interventions: BIOLOGICAL: [89Zr]Df-IAB2M
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 4-way Crossover QT Evaluation in Healthy Subjects
Status: COMPLETED
Conditions: Cardiac Repolarization in Healthy Subjects
Interventions: DRUG: ZTI-01|DRUG: Moxifloxacin 400mg|OTHER: Placebo IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT