pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Family Quality of Life Among Families With a Member Who is a Cancer Patient
Status: COMPLETED
Conditions: Breast Cancer|Colorectal Cancer|Head and Neck Cancer|Lung Cancer|Prostate Cancer|Solid Tumor
Interventions: OTHER: questionnaire administration|OTHER: survey administration|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immediate Dental Prosthesis Functionalization Protocol in People Over 70 Years of Age
Status: RECRUITING
Conditions: Dental Prosthesis Failure|Frail Elderly Syndrome
Interventions: PROCEDURE: Procedure: prosthetic functioning|DEVICE: Conventional dental prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Chemoradiotherapy for the Treatment of Unresectable Gastroesophageal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8|Localized Gastroesophageal Junction Adenocarcinoma|Locally Advanced Gastroesophageal Junction Adenocarcinoma|Pathologic Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8|Postneoadjuvant Therapy Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8|Postneoadjuvant Therapy Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8|Postneoadjuvant Therapy Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8|Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8|Postneoadjuvant Therapy Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8|Postneoadjuvant Therapy Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8|Unresectable Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Docetaxel|DRUG: Fluorouracil|DRUG: Oxaliplatin|BIOLOGICAL: Pembrolizumab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enzalutamide With Venetoclax in Treating Patients With Metastatic Castration Resistant Prostate Cancer
Status: COMPLETED
Conditions: Castration Levels of Testosterone|Castration-Resistant Prostate Carcinoma|Metastatic Prostate Carcinoma|Metastatic Prostate Carcinoma in the Soft Tissue|Prostate Carcinoma Metastatic in the Bone|PSA Progression|Stage IV Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: DRUG: Enzalutamide|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of So-Cheong-Ryong-Tang on Perennial Allergic Rhinitis
Status: UNKNOWN
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: SCRT|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Exploration of Anticoagulation Program in Cerebral Aneurysm and Arteriovenous Malformations With Hybrid Operation 2
Status: UNKNOWN
Conditions: Cerebral Aneurysm|Arteriovenous Malformations
Interventions: DRUG: Heparin Sodium|DRUG: Heparin Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Trial Measuring ART-123 Ability to Prevent Sensory Neuropathy in Unresectable mCRC Subjects w/Oxaliplatin-based Chemo
Status: WITHDRAWN
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: DRUG: thrombomodulin alfa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Mesenchymal Stem Cells(MSCs) Transplantation for Acute Cerebral Infarction Patients
Status: RECRUITING
Conditions: Infarction, Middle Cerebral Artery|Infarction, Anterior Cerebral Artery|Cerebral Infarction|Stroke, Ischemic|Acute Stroke|Brain Infarction|Infarction, PCA|Infarction, Posterior Circulation, Brain
Interventions: BIOLOGICAL: human umbilical cord mesenchymal stem cells|BIOLOGICAL: Placebo|OTHER: standardized treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacodynamics After Single Oral Dosing of Tegoprazan, EAPA115 and RAPA115 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tegoprazan 50 mg|DRUG: EAPA115|DRUG: RAPA115
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QL1706 Plus Chemotherapy as Neoadjuvant Therapy in Early High-Risk TNBC Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Early Breast Cancer|Neoadjuvant Therapy|TNBC, Triple Negative Breast Cancer
Interventions: DRUG: Bispecific antibody (bsAb) targeting PD-1 and CLTA-4|DRUG: Albumin-bound paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study Evaluating the Safety, Tolerability and Pharmacokinetics of Trebananib (AMG 386 ) in Adult Japanese Participants With Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms, Advanced Solid
Interventions: DRUG: Trebananib 3 mg/kg|DRUG: Trebananib 10 mg/kg|DRUG: Trebananib 30 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Supraclavicular Block and Interscalene Analgesia Versus an Intercostobrachial Nerve Block Versus PCA in Forearm Surgery
Status: RECRUITING
Conditions: Forearm Surgery|US-Guided Supraclavicular Block|Interscalene Analgesia|Tourniquet Pain
Interventions: DRUG: bupivacaine, midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of COVID-19 on Sinus Augmentation Surgery
Status: COMPLETED
Conditions: Bone Loss
Interventions: PROCEDURE: Sinus lift in patients with positive COVID-19 history|PROCEDURE: Sinus lift with negative COVID-19 history
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Single Port and Four Port Laparoscopic Gallbladder Removal
Status: COMPLETED
Conditions: CHOLELITHIASIS
Interventions: PROCEDURE: Single-port cholecystectomy|PROCEDURE: Four-port laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Demonstrate Bioequivalence Between Lorcaserin Extended Release (XR) Tablets Manufactured in Kawashima and Lorcaserin XR Tablets Manufactured in Zofingen in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Lorcaserin manufactured at Zofingen|DRUG: Lorcaserin manufactured at Kawashima
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 1/2 Sequentially Staged Safety Study in Healthy Subjects and Subjects With Mild Acne
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: Lemuteporfin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phototherapy For Treatment Of Raynaud's Phenomenon
Status: WITHDRAWN
Conditions: Raynaud Disease|Raynaud Phenomenon|Raynaud Syndrome
Interventions: DEVICE: Blue Light Therapy|DEVICE: Sham Light Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The DIAMOND Study: Distensibility Improvement And Remodeling in Diastolic Heart Failure
Status: COMPLETED
Conditions: Heart Failure, Congestive|Dyspnea|Pulmonary Edema
Interventions: DRUG: ALT-711
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin Reduces Chronic Inflammation and aVerage Epogen Dose (ARChIVED)
Status: WITHDRAWN
Conditions: Complication of Renal Dialysis
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Prazosin on the Urinary Sodium Excretion Response to Mental Stress
Status: COMPLETED
Conditions: Hypertension|Stress, Psychological|Blood Pressure
Interventions: DRUG: Prazosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cabozantinib for Plexiform Neurofibromas (PN) in Subjects With NF1 in Children and Adults
Status: COMPLETED
Conditions: NF1|Neurofibromatosis|Plexiform Neurofibromas
Interventions: DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Spry Belt Treatment on Bone Turnover Marker Profile
Status: COMPLETED
Conditions: Osteopenia|Low Bone Density
Interventions: DEVICE: Spry Belt|DEVICE: Sham Spry Belt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Electroencephalographia as Predictor of Effectiveness HD-tDCS in Neuropathic Pain: Machine Learning Approach
Status: UNKNOWN
Conditions: Traumatic Brachial Plexus Lesion|Chronic Pain
Interventions: DEVICE: Neurostimulation (High Definition - transcranial Direct Current Stimulation) HD-tDCS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Integrating Chiropractic Care and Mind-Body Training for the Treatment of Nonspecific Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain|Nurse-Patient Relations
Interventions: PROCEDURE: Combined chiropractic care and Tai Chi
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Find the Best Dosing Schedule for Delavirdine, Zidovudine, and Indinavir in HIV-Positive Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Delavirdine mesylate|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Unravelling the Impact of Radiofrecuency in Liver Surgery: the Key to Decrease Local Recurrence?
Status: RECRUITING
Conditions: Liver Cancer|Cancer, Treatment-Related
Interventions: PROCEDURE: Additional margin coagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Intensive Lipid Lowering Treatment in Non-ST-elevation Acute Coronary Syndrome (NSTE-ACS) Patients
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Atorvastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clonidine vs. Dexmedetomidine in Agitated Delirium in Intensive Care Patients
Status: UNKNOWN
Conditions: Delirium|Critical Illness
Interventions: DRUG: Clonidine|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-BCMA CAR-NK Cell Therapy for the Relapsed or Refractory Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma, Refractory
Interventions: BIOLOGICAL: Anti-BCMA CAR-NK Cells|DRUG: Fludarabine|DRUG: Cytoxan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vernakalant (Oral) Prevention of Atrial Fibrillation Recurrence Post-Conversion Study
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Placebo|DRUG: Vernakalant (oral)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Cavosonstat (N91115) in Patients With CF Homozygous for the F508del-CFTR Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Cavosonstat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Immune Responses After Hepatitis B Revaccination Doses in a Young Cohort
Status: RECRUITING
Conditions: Hepatitis B|Vaccination; Infection|Preventable Disease, Vaccine
Interventions: BIOLOGICAL: recombinant hepatitis B vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase III Study to Demonstrate the Safety and Efficacy of DWP-450 to Treat Glabellar Lines - EV-002
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: BIOLOGICAL: Botulinum toxin, Type A|OTHER: 0.9% sterile, unpreserved saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New Generation IGRA in Immunocompromised Individuals
Status: UNKNOWN
Conditions: Monitoring, Immunologic|Active Tuberculosis|Tuberculosis in Solid Organ Transplant Recipients|Tuberculosis in Marrow Transplant Recipients|Tuberculosis in Rheumatoid Arthritis|Tuberculosis in Chronic Renal Failure|Tuberculosis in HIV-infected Individuals
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neoadjuvant Nivolumab and Relatlimab in Merkel Cell Carcinoma
Status: RECRUITING
Conditions: Merkel Cell Carcinoma
Interventions: DRUG: Nivolumab 240 mg / Relatlimab 80 mg in a fixed dose combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Belimumab Combined With Multi-target Induction Therapy in Lupus Nephritis
Status: RECRUITING
Conditions: Lupus Nephritis|Remission|Safety Issues
Interventions: DRUG: Methylprednisolone Injectable Suspension|DRUG: Belimumab Injection|DRUG: Immunosuppressive Agents
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Shoulder Surgery With Administration of Intravenous Tranexamic Acid
Status: COMPLETED
Conditions: Rotator Cuff Tears|Shoulder Arthorscopy Surgery|Surgical Blood Loss|Tranexamic Acid
Interventions: DRUG: Tranexamic Acid 100Mg/Ml Inj Vil 10Ml|DRUG: 0.9% Sodium Chloride Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microwave Ablation Combined With Camrelizumab in the Treatment of Early Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: Microwave Ablation|DRUG: Camrelizumab|PROCEDURE: Breast Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Polyglucosamine L112 on Serum Surrogate Markers of Cholesterol Absorption
Status: COMPLETED
Conditions: Cholesterol Lowering
Interventions: DEVICE: Polyglucosamine L112
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pediatric Antibiotic Dosing in Extracorporal Membrane Oxygenation (PADECMO)
Status: RECRUITING
Conditions: Pharmacokinetics|Amoxicillin-clavulanate|Piperacillin-tazobactam|Meropenem|Cefazolin|Teicoplanin|Vancomycin|Ciprofloxacin|Amikacin
Interventions: OTHER: Amoxicillin-clavulanate|OTHER: Piperacillin-tazobactam|OTHER: Meropenem|OTHER: Cefazolin|OTHER: Vancomycin|OTHER: Teicoplanin|OTHER: Ciprofloxacin|OTHER: Amikacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Combining Intraoperative Radiotherapy With Kyphoplasty for Treatment of Spinal Metastases
Status: UNKNOWN
Conditions: Spinal Metastasis
Interventions: RADIATION: IORT with Kyphoplasty|DEVICE: Intrabeam®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endocuff-assisted Versus Cap-assisted Versus Standard Colonoscopy
Status: COMPLETED
Conditions: Colorectal Polyps|Colorectal Adenomas
Interventions: DEVICE: Arc Endocuff (AEC 110, 120, 130, 140)|DEVICE: Cap|DEVICE: Standard colonoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Veliparib in Treating Patients With Malignant Solid Tumors That Do Not Respond to Previous Therapy
Status: COMPLETED
Conditions: Basal-Like Breast Carcinoma|BRCA1 Mutation Carrier|BRCA2 Mutation Carrier|Breast Carcinoma|Estrogen Receptor Negative|HER2/Neu Negative|Hereditary Breast and Ovarian Cancer Syndrome|Ovarian Carcinoma|Pancreatic Carcinoma|Progesterone Receptor Negative|Prostate Carcinoma|Recurrent Breast Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Solid Neoplasm|Triple-Negative Breast Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Assessing Zactima Against Placebo in Prostate Cancer Subjects Undergoing Intermittent Androgen Deprivation Hormonal Therapy
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: vandetanib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRecisiOn Medicine In StrokE: Evolution of Plasma Brain-Derived Tau in Acute Stroke
Status: RECRUITING
Conditions: Stroke|Stroke, Acute|Stroke, Ischemic|Cerebrovascular Disorders|Brain Diseases|Central Nervous System Diseases|Brain Ischemia|Nervous System Diseases
Interventions: DIAGNOSTIC_TEST: Plasma levels of BD-tau
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Tolerability of IC83/LY2603618 Administered After Pemetrexed 500 mg/m2 Every 21 Days in Patients With Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: IC83/LY2603618|DRUG: IC83/LY2603618|DRUG: IC83/LY2603618|DRUG: IC83/LY2603618|DRUG: IC83/LY2603618|DRUG: pemetrexed|DRUG: pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Muscle Strength Training in Adults With Obesity
Status: RECRUITING
Conditions: Obesity
Interventions: DEVICE: High-resistance inspiratory muscle strength training|DEVICE: Very-low-resistance inspiratory muscle strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of mFOLFOX6 + Trastuzumab + Avelumab in Gastric and Esophageal Adenocarcinomas
Status: COMPLETED
Conditions: Gastric Adenocarcinoma|Esophageal Adenocarcinoma|Metastasis|HER-2 Gene Amplification
Interventions: DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: 5 fluorouracil|DRUG: Trastuzumab|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RemI for Post-Bariatric Surgery Weight Regain
Status: RECRUITING
Conditions: Obesity|Bariatric Surgery Candidate
Interventions: BEHAVIORAL: Acceptance-Based Behavioral Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surfactant Nebulization for the Early Aeration of the Preterm Lung
Status: COMPLETED
Conditions: Preterm Birth|Respiratory Distress Syndrome|Surfactant Deficiency Syndrome Neonatal
Interventions: DRUG: Surfactant nebulisation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate of the Effects of Opioid Exposure on the Ability of the Diaphragm Muscle
Status: RECRUITING
Conditions: Respiratory Function Loss|Respiratory Complication
Interventions: DRUG: Fentanyl Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Eyelash Growth From Application of Bimatoprost in Gel Suspension to the Base of the Eyelashes
Status: COMPLETED
Conditions: Hypertrichosis
Interventions: DRUG: Bimatoprost Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The BIomarker Guided Study for Depression
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Guanfacine Pill|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Fluticasone Propionate(FP)/ Salmeterol Xinafoate (SLM) Hydro Fluoro Alkane (HFA) Metered Dose Inhaler (MDI) in Pediatric Patients With Bronchial Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: FP/ SLM HFA MDI 50/25 mcg|DRUG: FP HFA MDI 50 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ARNI Versus plAcebo in Patients With Congenital sYStemic Right Ventricle Heart Failure
Status: TERMINATED
Conditions: Systemic Right Ventricle|Heart Failure
Interventions: DRUG: Sacubitril / Valsartan Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Sagittarius Trial
Status: NOT_YET_RECRUITING
Conditions: Colon Cancer Stage II|Colon Cancer Stage III
Interventions: DRUG: Oxaliplatin|DRUG: Capecitabine|DRUG: Folinic acid|DRUG: Fluorouracil|DRUG: Temozolomide|DRUG: Irinotecan|DRUG: Nivolumab|DRUG: Ipilimumab|DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study to Evaluate the Safety and Efficacy of Galnobax® in Treating Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: Esmolol Hydrochloride|OTHER: Only Standard of Care|OTHER: Vehicle Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Study in Patient With Chronic Obstructive Pulmonary Disease (0000-036)
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Fluticasone|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, PD & PK of Multiple Doses of Peginesatide for Anemia in Chronic Kidney Disease Patients
Status: COMPLETED
Conditions: Anemia|Chronic Kidney Disease|Chronic Renal Failure
Interventions: DRUG: peginesatide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of COMP360 Psilocybin Therapy in Anorexia Nervosa: a Proof-of-concept Study
Status: RECRUITING
Conditions: Anorexia Nervosa
Interventions: DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of a Pharmacist-led Patient-centred Care Intervention Along With Text-Message Reminders, on the Management of Newly Diagnosed Tubercular Patients: a Protocol for a Randomized Controlled Trial'.
Status: COMPLETED
Conditions: Pulmonary TB|TB
Interventions: BEHAVIORAL: New management mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Scandinavian Cystic Fibrosis Azithromycin Study
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Study medication, azithromycin or placebo|DRUG: Azithromycin or placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, Preliminary Efficacy and Pharmacokinetics of Simmitecan Monotherapy and Combination in Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Solid Tumor|Advanced/Metastatic Colorectal Cancer
Interventions: DRUG: Simmitecan|DRUG: 5-fluorouracil and Leucovorin Calcium|DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Artificial Intelligence by Urogynecologic Patients
Status: RECRUITING
Conditions: Uterovaginal Prolapse|Urinary Incontinence|Lower Urinary Tract Symptoms
Interventions: BEHAVIORAL: Use of ChatGPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pilot Study of Pioglitazone for the Treatment of Moderate to Severe Asthma in Obese Asthmatics
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: pioglitazone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Paclitaxel With GDC-0941 Versus Paclitaxel With Placebo in Participants With Locally Recurrent or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: GDC-0941|DRUG: Placebo|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Physical Therapy Intervention for Puerperal Mastitis
Status: COMPLETED
Conditions: Mastitis
Interventions: OTHER: Education|OTHER: Therapeutic ultrasound|OTHER: Sham ultrasound|OTHER: Breast massage|OTHER: Usual obstetric care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Empiric Therapy of Mucopurulent Cervicitis (MPC)
Status: TERMINATED
Conditions: Vaginitis Bacterial|Cervicitis
Interventions: OTHER: Placebo|DRUG: Azithromycin|DRUG: Cefixime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Telcagepant (MK-0974) in Participants With Moderate to Severe Acute Migraine With or Without Aura (MK-0974-011)
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Telcagepant potassium 150 mg|DRUG: Telcagepant potassium 300 mg|DRUG: Zolmitriptan 5 mg|DRUG: Placebo to telcagepant 150 mg|DRUG: Placebo to tecagepant 300 mg|DRUG: Placebo to zolmitriptan 5 mg|DRUG: Rescue medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Triple Treatment for Detachment of Retinal Pigment Epithelium Secondary to Polypoidal Choroidal Vasculopathy
Status: WITHDRAWN
Conditions: Choroidal Neovascularization|Retinal Pigment Epithelial Detachment
Interventions: OTHER: Triple Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of M2951 in SLE
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Placebo|DRUG: M2951|DRUG: M2951|DRUG: M2951|DRUG: M2951
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Vegetarian Meal on the Physiology of Insulin Response in Patients With Type 2 Diabetes Mellitus and Obesity
Status: RECRUITING
Conditions: Type2diabetes|Obesity|Diet, Healthy|Nutrition, Healthy
Interventions: OTHER: Vegetarian Meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pemetrexed and Gemcitabine in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Lung Neoplasms
Interventions: DRUG: pemetrexed|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects OF NMES With and Without Dynamic Bracing on Spasticity and Movement Quality in CP
Status: RECRUITING
Conditions: Diplegic Spastic Cerebral Palsy
Interventions: OTHER: NMES with Dynamic Bracing|OTHER: NMES without Dynamic Bracing|OTHER: Dynamic Bracing Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Povorcitinib (INCB054707) in Participants With Moderate to Severe Hidradenitis Suppurativa (HS)
Status: RECRUITING
Conditions: Hidradenitis Suppurativa (HS)
Interventions: DRUG: Povorcitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LEO 90100 Aerosol Foam Compared to Calcipotriol Plus Betamethasone Dipropionate Gel in Subjects With Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: LEO 90100 aerosol foam|DRUG: Aerosol foam vehicle|DRUG: Calcipotriol BDP gel|DRUG: Gel vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nanofat Grafting as a Method of Treating Critical Limb Ischemia
Status: NOT_YET_RECRUITING
Conditions: Limb Ischemia
Interventions: PROCEDURE: nano-fat grafting in chronic limb ischaemia|PROCEDURE: sham comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Pembrolizumab in Recurrent or Metastatic HNSCC
Status: RECRUITING
Conditions: Metastatic Head and Neck Squamous Cell Carcinoma|Recurrent Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ACTR707 in Combination With Rituximab in Subjects With Relapsed or Refractory B Cell Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: BIOLOGICAL: ACTR707|BIOLOGICAL: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ILLUMENATE Below-The-Knee (BTK) Arteries: a Post Market Clinical Study
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: COMBINATION_PRODUCT: StellarexTM 0.014" Over-The-Wire Drug-coated Angioplasty Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Economic Comparison of 2 Methods of Intubation Tube Fixation : AnchorFastTM Versus Current Cord Fixation
Status: NOT_YET_RECRUITING
Conditions: Intubation Complication|Eschar
Interventions: PROCEDURE: Corded tube care|DEVICE: Tube care attached by AnchorFast|OTHER: Caregiver's evaluation on each tube fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Tenofovir Alafenamide(TAF) Reduces the Risk of Hepatocellular Carcinoma(HCC) Recurrence
Status: RECRUITING
Conditions: HCC Patients After Curative Treatment With Low HBV Viral Load
Interventions: DRUG: Vemlidy® (Tenofovir Alafenamide; TAF)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Montelukast and Fexofenadine Versus Montelukast and Levocetrizine Combination in Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Montelukast|DRUG: Fexofenadine|DRUG: Levocetrizine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lower Extremity Functional Training (LIFT) on Gross Motor Function and Gait in Children With Spastic CP
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: Lower Extremity Functional Training|OTHER: conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Assess the Immunogenicity of QL0605 Compared to US Neulasta in Healthy Subjects
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: QL0605|DRUG: US Neulasta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Diet and Medical Therapy Versus Bariatric Surgery in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: PROCEDURE: Bariatric surgery: Gastric bypass|PROCEDURE: Bariatric surgery: Bilio-pancreatic diversion|BEHAVIORAL: anti-diabetic drugs and behavioral suggestions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conduction System Pacing Versus Biventricular Resynchronization in Patients With Chronic Heart Failure
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure|Left Bundle-Branch Block|Cardiac Resynchronization|Conduction System Pacing
Interventions: DEVICE: Conduction system pacing|DEVICE: Biventricular pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Iron Therapy in Heart Failure With Preserved Ejection Fraction and Iron Deficiency (PREFER-HF)
Status: UNKNOWN
Conditions: Heart Failure With Normal Ejection Fraction|Ferropenic Anemia
Interventions: OTHER: Placebo|DRUG: Ferric carboxymaltose|DRUG: Ferroglycine Sulfate|DRUG: Sucrosomial Iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Telbivudine on Renal Function and Proteinuria in Patients With CHB & Chronic Renal Diseases
Status: WITHDRAWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Telbivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analyze the Predictive Value of Gene TMPRSS2-ETS in Response to Enzalutamide in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Hormone-refractory Prostate Cancer
Interventions: DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Emotion-Focused Skills Training for Parents
Status: COMPLETED
Conditions: F01.318 Child Rearing|F01.470 Emotions|F01.145.179 Child Behavior
Interventions: BEHAVIORAL: Emotion-Focused Skills Training for Parents - Experiential|BEHAVIORAL: Emotion-Focused Skills Training for Parents - Psychoeducational
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Havrix™ Co-Administered With a Diphtheria, Tetanus and Pertussis and a Haemophilus b Vaccine in Children Aged 15 Months
Status: COMPLETED
Conditions: Hepatitis A
Interventions: BIOLOGICAL: Havrix™|BIOLOGICAL: Infanrix™|BIOLOGICAL: ActHIB™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pelvic Floor Muscle Training Programme in Pregnant Nepalese Women- a Feasibility Study
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|Urinary Incontinence
Interventions: OTHER: Pelvic Floor Muscle Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Learning Oriented Physiotherapy - a New Approach
Status: COMPLETED
Conditions: Agitation|Anxiety|Dizziness|Pain|Numbness|Depression|Fatigue|Sleep Disturbances
Interventions: BEHAVIORAL: Learning Oriented Physiotherapy|BEHAVIORAL: Widely Recognized Psychiatric Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of A-PRF+ Versus Open Flap Debridement in the Treatment of Patients With Stage III Periodontitis
Status: COMPLETED
Conditions: Intrabony Periodontal Defect
Interventions: PROCEDURE: Advanced- platelets rich fibrin (A-PRF+) + Open flap debridement (OFD)|PROCEDURE: Open flap debridement (OFD) alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Calcium Dobesilate for Chronic Venous Wounds
Status: SUSPENDED
Conditions: Ulcer
Interventions: DRUG: Calcium Dobesilate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Massage Instrument Compared to Placebo for Upper Trapezius Muscle Pain
Status: COMPLETED
Conditions: Myofascial Pain Syndrome
Interventions: DEVICE: FascialEdge instrument|OTHER: Placebo electric point stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Response to Emerging Antimicrobial Resistance With Containment Microbiota Therapy (REACT)
Status: NOT_YET_RECRUITING
Conditions: Multi-Drug Resistant Organism Colonization
Interventions: DRUG: Allogeneic Microbiota in Glycerol (9%) (AMG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transcranial Direct Current Stimulation in Patients With Disorders of Consciousness
Status: COMPLETED
Conditions: Disorder of Consciousness
Interventions: DEVICE: real tDCS|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: One Week of Magnesium Supplementation Lowers IL-6, Perceived Pain and Increases Post Exercise Blood Glucose in Response to Downhill Running
Status: COMPLETED
Conditions: Magnesium Deficiency
Interventions: DIETARY_SUPPLEMENT: Magnesium oxide|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Combination of Lateral Foot Orthoses and Knee Brace for Treatment of the Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Combined treatment of medial knee osteoarthritis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dietary Interventions on Glycocalyx Dimensions in South Asian Patients With Diabetic Nephropathy.
Status: COMPLETED
Conditions: Diabetic Nephropathy Type 2|Albuminuria|Type2 Diabetes Mellitus|Glucose Metabolism Disorders|Microalbuminuria|Diabetic Nephropathies|Diabetic Complications Renal|Diabetes Mellitus|Kidney Diseases|South Asian
Interventions: OTHER: Fasting mimicking diet Prolon|DIETARY_SUPPLEMENT: Food supplement Endocalyx|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Dietary Nutrition Intervention Techniques for Children Obesity
Status: COMPLETED
Conditions: Obesity|Intestinal Bacteria Flora Disturbance|Body Weight
Interventions: DIETARY_SUPPLEMENT: Dietary nutrition based on plant fermentation extract|DIAGNOSTIC_TEST: MRI in quantifying liver fat with MRS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Switching From Tenofovir Disoproxil Fumarate to Besifovir Dipivoxil Maleate
Status: UNKNOWN
Conditions: Hepatitis B|Besifovir Dipivoxil Maleate|Tenofovir Disoproxil Fumarate
Interventions: DRUG: Besifovir Dipivoxil Maleate|DRUG: Tenofovir disoproxil fumarate(TDF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combining tDCS and Neurorehabilitation to Treat Age-related Deficits of Mobility and Cognition: UPfront Walking Study
Status: COMPLETED
Conditions: Mobility Limitation|Cognitive Impairment
Interventions: BEHAVIORAL: Neurorehabilitation of Standard Walking|BEHAVIORAL: Neurorehabilitation of Complex Walking|DEVICE: Sham Transcranial Direct Current Stimulation (Sham tDCS)|DEVICE: Active Transcranial Direct Current Stimulation (Active tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Application of Photodynamic Therapy and Diode Laser for Endodontic Therapy of Young Permanent Teeth
Status: COMPLETED
Conditions: Teeth, Endodontically-Treated
Interventions: DEVICE: Photodinamic therapy|DEVICE: Diode laser|DRUG: 0.5% Sodium hypochlorite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Avelumab Plus Cetuximab in Pre-treated RAS Wild Type Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer|RAS Wild Type
Interventions: DRUG: Avelumab|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Sarilumab (SAR153191/REGN88) on Top of Methotrexate in Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Sarilumab|DRUG: Placebo (for sarilumab)|DRUG: Methotrexate|DRUG: Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: Upadacitinib Dose A|DRUG: Dupilumab Dose A|DRUG: Upadacitinib Dose B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of High Intensity Interval Training and Cluster Training on Speed, Explosive Strength and Functional Performance
Status: RECRUITING
Conditions: High Intensity Interval Training|Functional Performance|Football Players
Interventions: OTHER: Tabata Training|OTHER: Cluster Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Comparative Assessment of Post Extraction Pain in Orthodontic Patients to Evaluate the Effects of Early Engagement of Tooth with Orthodontic Wires. a Single Center Randomized Clinical Trial (RCT)
Status: COMPLETED
Conditions: Orthodontic Extraction|Orthodontic Treatment|Orthodontic Treatment Via Premolar Extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Mindfulness and RelaxationTraining for Insomnia (MRTI) on Postmenopausal Women: a Randomized Clinical Trial.
Status: COMPLETED
Conditions: Primary Insomnia
Interventions: BEHAVIORAL: mindfulness training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT