pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety of FIAsp Compared to Insulin Aspart Both in Combination With Insulin Detemir in Adults With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: Faster-acting insulin aspart|DRUG: insulin detemir|DRUG: insulin aspart|DRUG: Faster-acting insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trans-Radial Coronary Interventions Using A Sheathless Guiding Catheter
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: trans-radial PCI (TRI)|PROCEDURE: trans-radial PCI (TRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain and Gut Plasticity in Mild TBI or Post-acute COVID Syndrome Following Growth Hormone Therapy
Status: COMPLETED
Conditions: Traumatic Brain Injury|Fatigue|Cognitive Impairment|COVID-19
Interventions: DRUG: Somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Placebo-controlled Trial of an AMPAkine in Major Depressive Disorder
Status: WITHDRAWN
Conditions: Major Depressive Disorder
Interventions: DRUG: ORG 24448|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Non-Surgical Periodontal Therapy on Rheumatoid Arthritis
Status: NOT_YET_RECRUITING
Conditions: Periodontitis|Rheumatoid Arthritis
Interventions: OTHER: ELISA (Enzyme-Linked ImmunoSorbent Assay)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Elafibranor in Patients With Primary Biliary Cholangitis (PBC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Biliary Cirrhosis
Interventions: DRUG: Elafibranor 80mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Analgesic Effects of Low Dose Tramadol/Acetaminophen Combination After Open Gynaecological Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: tramadol/acetaminophen|DRUG: acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serotonin Receptor Blockers in Ischemic Mitral Regurgitation
Status: RECRUITING
Conditions: Ischemic Mitral Regurgitation
Interventions: DRUG: Cyproheptadine 4 Mg Oral Tablet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Scars and Dysfunctions of the Pelvic Floor in Postpartum
Status: UNKNOWN
Conditions: Pelvic Floor Disorders
Interventions: OTHER: Pysiotherapy techniques|OTHER: physician treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: De-Escalation Protocol Of HPV Mediated Oropharyngeal Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Clinical Stage|Oropharynx Cancer
Interventions: PROCEDURE: Transoral robotic surgery|DRUG: Cisplatin - Dose Level 1|DRUG: Cisplatin - Dose Level 2|RADIATION: Dose Level 1|RADIATION: Dose Level 2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ingested Interferon Alpha: Prolongation or Permanence of the "Honeymoon" Phase in Newly Diagnosed Type 1 Diabetes Mellitus
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: interferon alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Bowel Ultrasound-based Treat to Target Versus Routine Treat to Target Strategies in Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis Chronic Moderate|Ulcerative Colitis Chronic Severe
Interventions: DIAGNOSTIC_TEST: bowel ultrasound|DIAGNOSTIC_TEST: colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating Safety of Etanercept in Treatment of Patients With Moderate to Severe Psoriasiswith Etanercept
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of SlumberCurve™ Following Rotator Cuff Surgery: A Randomized Control Trial
Status: WITHDRAWN
Conditions: Rotator Cuff Tears|Surgery|Pain, Postoperative
Interventions: DEVICE: Slumber Curve sleep aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Health Protection and Promotion Training Programs on the Health Behavior of Older People
Status: NOT_YET_RECRUITING
Conditions: Older People|Health Promotion
Interventions: BEHAVIORAL: Peer-Led Health Protection and Promotion Training Program|BEHAVIORAL: Health Protection and Promotion Training Program under the Leadership of a Public Health Nurse
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Reducing Heart Failure Re-admissions by Enhancing Sleep Apnea Treatment Adherence
Status: COMPLETED
Conditions: Congestive Heart Failure|Sleep Apnea Syndromes
Interventions: BEHAVIORAL: AirCare App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of TAK-071 in Healthy Participants and Participants With Mild Cognitive Impairment/Mild Alzheimer Disease and Relative Bioavailability (BA) and Food Effect of TAK-071 in Healthy Participants
Status: TERMINATED
Conditions: Alzheimer Disease|Healthy Volunteers
Interventions: DRUG: TAK-071|DRUG: Donepezil|DRUG: TAK-071 Placebo|DRUG: Donepezil Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment With Nivolumab at the Fixed Dose 40 mg (Nivo40) in Patients With Relapsed/Refractory Hodgkins Lymphoma
Status: COMPLETED
Conditions: Hodgkin Lymphoma
Interventions: DRUG: Nivolumab 40 mg in 4 ml Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auto Continuous Positive Airway Pressure (CPAP) Based Energy Spectrum Analysis of Flow for Treatment of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: SleepStyle 200 Auto Series CPAP Humidifier
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exogenous Oxidation of Fructose-glucose Mixtures During Running
Status: COMPLETED
Conditions: Exercise
Interventions: DIETARY_SUPPLEMENT: Fructose-maltodextrin|DIETARY_SUPPLEMENT: Fructose-maltodextrin hydrogel|DIETARY_SUPPLEMENT: Glucose-maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Scalp Infiltration With Methylprednisolone Plus Ropivacaine for Post-Craniotomy Pain in Children
Status: UNKNOWN
Conditions: Pain, Postoperative|Post-Craniotomy Headache
Interventions: DRUG: Methylprednisolone|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lenalidomide in Treating Older Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Adult Acute Basophilic Leukemia|Adult Acute Eosinophilic Leukemia|Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Secondary Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Gather Information on the Acceptability of a New Flavor System With Increasing Levels of 2, 4, 6 g or Higher of Mannitol for PEG 3350 in Subjects Having Infrequent Bowel Movements.
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Polyethylene glycol (MiraLAX, BAY81-8430)|DRUG: Mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Fentanyl 25 μg/h Transdermal System
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fentanyl 25 μg/h transdermal system, single application|DRUG: Duragesic 25 μg/h transdermal system single application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: NUDGE-EHR Replication Trial at Mass General Brigham
Status: ACTIVE_NOT_RECRUITING
Conditions: Aging|Benzodiazepine Sedative Adverse Reaction|Anticholinergic Adverse Reaction|Adverse Drug Event
Interventions: OTHER: Follow-up booster Alert|OTHER: Pre-commitment|OTHER: Enhanced Alert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PACCE: Panitumumab Advanced Colorectal Cancer Evaluation Study
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Oxaliplatin Based Chemotherapy|DRUG: Panitumumab|DRUG: Irinotecan Based Chemotherapy|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation in Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: OTHER: Fecal transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 4FMFES-PET Imaging of Endometrial and Ovarian Cancers
Status: COMPLETED
Conditions: Endometrial Cancer|Ovarian Cancer
Interventions: DRUG: Loperamide Pill|DRUG: hyoscine-n-butylbromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 12-Week No-Rofecoxib Plus Aspirin Endoscopy Study (0782-003)
Status: TERMINATED
Conditions: Arthritis, Rheumatoid|Osteoarthritis
Interventions: DRUG: MK0782
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Testing Ketamine Sublingual Wafer After Wisdom Tooth Extraction
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ketamine|DRUG: Placebo (for Ketamine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Utility of Measuring the Circadian Clock in Treatment of Delayed Sleep-Wake Phase Disorder
Status: COMPLETED
Conditions: Delayed Sleep Phase Syndrome
Interventions: DRUG: Melatonin 0.5 MG|OTHER: Dim Light Melatonin Onset (salivary)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Balneotherapy With Mineral Water Named" Debole of Vetriolo" in Fibromyalgia Syndrome
Status: COMPLETED
Conditions: Fibromyalgia Syndrome
Interventions: OTHER: Balneotherapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study Evaluating the Efficacy and Safety of Retinoic Acid in Patients With 15q11-q13 Duplication Syndrome
Status: UNKNOWN
Conditions: Autism|Treatment Adherence|Retinoic Acid|Dup15Q Syndrome
Interventions: DRUG: Retinoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Early Non Invasive Ventilation in Amyotrophic Lateral Sclerosis (ALS) Patients
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DEVICE: Home pressure ventilator model Vivo 40 (BREAS Medical AB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dyspnea in Hypermobile Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorder
Status: RECRUITING
Conditions: Hypermobile EDS (hEDS)|Hypermobility Syndrome
Interventions: BEHAVIORAL: Usual Care plus Inspiratory Muscle Training (IMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab in Combination With Metronomic Chemotherapy in Paediatrics Refractory / Relapsing Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Childhood Solid Tumor
Interventions: DRUG: Vinblastine|DRUG: Cyclophosphamide|DRUG: Capecitabine|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of Prograf and MR4 in Kidney Transplantation Patients
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Prograf|DRUG: MR4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wheeling to Healing: A Novel Method for Improving Healing of Diabetic Foot Ulceration
Status: RECRUITING
Conditions: Diabetes Mellitus
Interventions: DEVICE: Wheeled Knee Walker|OTHER: Usual and Customary Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Roche Liat Flu/RSV Assay for Management of Influenza in the Emergency Department
Status: COMPLETED
Conditions: Influenza, Human
Interventions: DIAGNOSTIC_TEST: Procalcitonin|OTHER: Pharmacist-Led Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Entospletinib Plus Intensive Induction/Consolidation Chemotherapy in Newly Diagnosed NPM1-mutated AML
Status: TERMINATED
Conditions: Nucleophosmin 1-mutated Acute Myeloid Leukemia
Interventions: DRUG: Entospletinib|DRUG: Placebo|DRUG: Cytarabine|DRUG: Anthracycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study for Patients With Indolent Non-follicular Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Indolent Non-follicular|Non-Hodgkin's Lymphoma
Interventions: DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AntiCoagulation Tracking InterVention and Evaluation
Status: WITHDRAWN
Conditions: Anticoagulation|Atrial Fibrillation|Atrial Flutter|Pulmonary Embolus/Emboli|Deep Vein Thrombosis|Stroke|Hypercoagulability
Interventions: OTHER: Panel Management for Anticoagulation Therapy|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phytosterols, Ezetimibe, and Cholesterol Metabolism
Status: COMPLETED
Conditions: Hypercholesterolemia|Coronary Heart Disease
Interventions: DRUG: Ezetimibe|OTHER: Phytosterols + ezetimibe|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Vitamin A With and Without Zinc and Multivitamin Supplementation on Malaria Morbidity in Ghanaian Children
Status: COMPLETED
Conditions: Malaria
Interventions: DIETARY_SUPPLEMENT: Vitamin A|DIETARY_SUPPLEMENT: Vitamin A and ZInc|DIETARY_SUPPLEMENT: Vitamin A , Zinc and Multivitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Continuous Positive Airway Pressure Therapy Withdrawal in Patients With Obstructive Sleep Apnea: A Randomized Trial
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Withdrawal of Continuous Positive Airway Pressure device|DEVICE: Alternation usage of Continuous Positive Airway Pressure Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Effectiveness of JNJ-16269110 (R256918) in Overweight and Obese Patients
Status: COMPLETED
Conditions: Obesity|Nutritional and Metabolic Diseases|Metabolic Diseases|Nutrition Disorders|Overweight
Interventions: DRUG: placebo|DRUG: R256918|DRUG: R256918|DRUG: R256918
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Training Effects of Rhythmic Auditory Stimulation on Gait in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Continuous Rhythmic Auditory Stimulation|Intermittent Rhythmic Auditory Stimulation
Interventions: OTHER: Rhythmic Auditory Stimulation (RAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Back and Neck Pain in an Emergency Room Setting
Status: COMPLETED
Conditions: Back Pain|Neck Pain|Anxiety|Range of Motion
Interventions: PROCEDURE: Real Acupuncture|PROCEDURE: Placebo Acupuncture|PROCEDURE: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Neurodevelopmental Trajectories in Children According to the Glycemic Profile Associated With Different Early Treatment Modalities in Children With Type 1 Diabetes (T1DM)
Status: NOT_YET_RECRUITING
Conditions: Diabetes
Interventions: DEVICE: AIDS|OTHER: Brain MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, PK and PD Relationships of RLS-0071 in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Status: RECRUITING
Conditions: Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Interventions: DRUG: RLS-0071|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Valganciclovir (Valcyte) for Chronic Fatigue Syndrome Patients Who Have Elevated Antibody Titers Against Human Herpes Virus 6 (HHV-6)and Epstein-Barr Virus (EBV)
Status: COMPLETED
Conditions: Chronic Fatigue Syndrome
Interventions: DRUG: valganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Short Title: Standard vs. Lower Pressure Pneumoperitoneum
Status: RECRUITING
Conditions: Laparoscopic Surgery
Interventions: OTHER: Carbon dioxide|DRUG: Bupivacaine|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Does Nerve Block + Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hrs?
Status: RECRUITING
Conditions: Migraine
Interventions: DRUG: Dexamethasone Oral|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PENG Block Plus Local Infiltration Compared to PENG Block Alone in Hip Surgery
Status: RECRUITING
Conditions: Pain|Hip Fractures|Postoperative Pain|Postoperative Analgesia
Interventions: OTHER: PENG block with or without local anaesthetic infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Clinical Efficacy of Precious Metal Fiber Textile (Germanium Titanium π Element) for Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DEVICE: underpants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Selonsertib in Participants With Moderate to Advanced Diabetic Kidney Disease
Status: COMPLETED
Conditions: Diabetic Kidney Disease
Interventions: DRUG: SEL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nebulized Epoprostenol (FLOLAN) and Phenylephrine on One Lung Ventilation (OLV)
Status: COMPLETED
Conditions: Oxygenation During One Lung Ventilation
Interventions: DRUG: Inhaled Epoprostenol and phenylephrine|DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hospitalization Rates of Patients With Non-Small Cell Lung Cancer Treated With Gemcitabine and Either Cisplatin or Carboplatin
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: cisplatin|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Pharmacokinetics of NTM-1633 vs Placebo Administered Intravenously in Healthy Adults
Status: COMPLETED
Conditions: Botulism
Interventions: BIOLOGICAL: NTM-1633|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Sunitinib in Patients With Advanced/Inoperable Fibrolamellar Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma|Fibrolamellar Hepatocellular Carcinoma
Interventions: DRUG: Sutent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sulindac and Plant Compounds in Preventing Colon Cancer
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DIETARY_SUPPLEMENT: curcumin|DIETARY_SUPPLEMENT: rutin|DRUG: quercetin|DRUG: sulindac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Can Calcium Ionophore Application Enhance the ICSI Outcomes in Severe Male Factor Infertility?
Status: UNKNOWN
Conditions: In Vitro Fertilization|Male Factor Infertility
Interventions: DRUG: Ca Ionophore A23187|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Sample Collection in Geriatric Patients
Status: COMPLETED
Conditions: Venipuncture Site Bruise
Interventions: OTHER: 20 N pressure for 1 minute|OTHER: 20 N pressure for 3 minute|OTHER: 20 N pressure for 5 minute
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Different Approach to Preventing Thrombosis
Status: COMPLETED
Conditions: Venous Thromboembolism|Pulmonary Embolism
Interventions: DRUG: VTE prophylaxis with Enoxaparin 30mg BID|DRUG: VTE prophylaxis with Aspirin 81mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Physical Activity Intervention in ELderly Patients With Myocardial INfarction
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocardial Infarction|Aging
Interventions: OTHER: Health Education|OTHER: Multi-domain lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Posaconazole Boosted Fosamprenavir
Status: COMPLETED
Conditions: HIV Infection|Fungal Infection
Interventions: DRUG: Posaconazole|DRUG: Fosamprenavir|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tacrolimus Treatment for Refractory Autoimmune Cytopenia
Status: UNKNOWN
Conditions: Autoimmune Hemolytic Anemia|Pure Red Cell Aplasia|Evans Syndrome
Interventions: DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantitative MRI of Bone Marrow Fat Fraction in Patients With Trepanobiopsy
Status: RECRUITING
Conditions: Aplastic Anemia|Aplastic Anemia Idiopathic
Interventions: DIAGNOSTIC_TEST: Bone marrow cellularity by mDixon-quant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Adrenaline Concentration on Intraoperative Hemodynamics of Liposuction Patients
Status: COMPLETED
Conditions: Intraoperative Hemodynamics|Liposuction
Interventions: DRUG: Epinephrine concentration of 1:1000000|DRUG: Epinephrine concentration of 1:500000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Patient-Centered Risk Adjusted Surveillance After Curative Resection of Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Interviews - Colorectal Cancer Participants|BEHAVIORAL: Questionnaire|BEHAVIORAL: Focus Groups|BEHAVIORAL: Interviews - Caregivers of Colorectal Cancer Participants
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dual TORC1/TORC2 Inhibitor ATG-008 (CC-223) in HBV Positive Advanced Hepatocellular Carcinoma (HCC) Subjects
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: ATG-008
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human-like Robotic Controllers for Enhanced Motor Learning
Status: RECRUITING
Conditions: Stroke|Spinal Cord Injuries
Interventions: BEHAVIORAL: Behavioral Interaction Conditions|DEVICE: Haptic Impedance Level|BEHAVIORAL: Skill Level of Partner|DEVICE: Robot Controller Showcase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose Escalated MRSI Guided Radiation Therapy in Glioblastoma
Status: TERMINATED
Conditions: Glioblastoma
Interventions: RADIATION: Intensity Modulated Radiation Therapy|DRUG: Temozolomide|BEHAVIORAL: Functional Assessment of Cancer Therapy-Brain (FACT-Br)|RADIATION: Stereotactic Radiosurgery Boost|RADIATION: Simultaneous Integrated Boost|DEVICE: 3D MRSI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Vs Late Post Traumatic Cataract Surgery
Status: COMPLETED
Conditions: Traumatic Cataract
Interventions: PROCEDURE: early cataract surgery & IOL implantation|PROCEDURE: late cataract surgery & IOL implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 28-day Repeat Dose Study of GSK573719
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK573719 125mcg|DRUG: GSK573719 250mcg|DRUG: GSK573719 500mcg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROSPECTIVE OPEN LABEL CLINICAL TRIAL TO ADMINISTER A BOOSTER DOSE OF PFIZER/BIONTECH OR MODERNA COVID-19 VACCINE IN HIGH-RISK INDIVIDUALS
Status: UNKNOWN
Conditions: SARS CoV 2 Infection|COVID-19
Interventions: BIOLOGICAL: Pfizer/BioNTech (BNT162b2)|BIOLOGICAL: Moderna
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: First-Voided Urinary LH vs. GnRH-stimulation in Differentiating Slowly- From Rapidly Progressive-Precocious Puberty
Status: UNKNOWN
Conditions: Precocious Puberty, Gonadotropin-dependent
Interventions: OTHER: Measurement of LH in first-voided urine|OTHER: collection of first-voided urine sample for LH level
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: BIP in Jämtland Härjedalen: Increased Access to CBT Within Regular Health Care in Northern Sweden
Status: COMPLETED
Conditions: Anxiety Disorder|Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: ICBT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: USF Hemostasis: USage of HemCon for Femoral Hemostasis After Percutaneous Procedures
Status: COMPLETED
Conditions: Coronary Angiography
Interventions: DEVICE: HemCon bandage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: STEVIE: A Study of Vismodegib in Patients With Locally Advanced or Metastatic Basal Cell Carcinoma
Status: COMPLETED
Conditions: Basal Cell Carcinoma
Interventions: DRUG: vismodegib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Chronic Cervicogenic Head and Neck Pain
Status: RECRUITING
Conditions: Cervicogenic Headache|Neck Pain, Posterior
Interventions: COMBINATION_PRODUCT: Osteopathic Manipulative Therapy and Exercise Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of PEX168 in Monotherapy Diabetes Mellitus Type 2 Patients
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: PEX168(100µg)|DRUG: PEX168(200µg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Precision Study on Vibration Induced Nystagmus Test for SCDS by Ortofone B250 Skull Vibration Protocol
Status: RECRUITING
Conditions: Superior Canal Dehiscence Syndrome|Vestibular Disorder
Interventions: DIAGNOSTIC_TEST: vibration induced nystagmus test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: R. I. S. POS. T. A
Status: UNKNOWN
Conditions: Vacuum Extraction; Failure, Affecting Fetus or Newborn|Persistent Occiput Posterior Position During Labor|Complication of Delivery
Interventions: OTHER: Digital examination|OTHER: Sonography evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Postoperative Adjuvant Treatment of Completely Resected Mucosal Melanoma Phase II Study
Status: RECRUITING
Conditions: Mucosal Melanoma
Interventions: COMBINATION_PRODUCT: Toripalimab|COMBINATION_PRODUCT: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants With PSMA PET-Positive Castration-Resistant Prostate Cancer
Status: RECRUITING
Conditions: PSMA PET-Positive Castration-Resistant Prostate Cancer
Interventions: BIOLOGICAL: In-111 rosopatamab tetraxetan|BIOLOGICAL: 45 KBq/kg Ac-225 rosopatamab tetraxetan|BIOLOGICAL: 55 KBq/kg Ac-225 rosopatamab tetraxetan|BIOLOGICAL: 60 KBq/kg Ac-225 rosopatamab tetraxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 3-day Course for CFS/ME
Status: RECRUITING
Conditions: Chronic Fatigue Syndrome|Myalgic Encephalomyelitis
Interventions: BEHAVIORAL: A 3-day course|BEHAVIORAL: Waiting list
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Locally Injected Vit D as a Non-surgical Modality for Periodontal Regeneration of Infrabony Defects
Status: COMPLETED
Conditions: Periodontal Bone Loss|Periodontal Pocket
Interventions: DIETARY_SUPPLEMENT: locally injected vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Magnesium Sulphate Neuroprotective Strategies for Preterm Deliveries
Status: RECRUITING
Conditions: Premature Birth|NEUROPROTECTION|MAGNESIUM SULPHATE|Cerebral Palsy|Neonatal Death
Interventions: DRUG: Magnesium sulfate loading with maintenance dose|DRUG: Magnesium sulfate loading dose only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability of the Preservative-free Ophthalmic Solution PRO-122 Compared With Krytantek Ofteno®
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: PRO-122|DRUG: Krytantek Ofteno®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lung Ultrasound Guided Protocol for Fluid Management for the Critically Ill Patient: a Randomized Study
Status: UNKNOWN
Conditions: Critical Illness
Interventions: OTHER: Fluid management guided by BLS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-surgical Antisepsis of Hands After Washing With Triclosan 0.5% Compared to Propan-1-ol 60%
Status: COMPLETED
Conditions: Antisepsis
Interventions: DRUG: Triclosan 0.5 % Topical Solution|DRUG: propanolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Patients With Previously Untreated Diffuse Large B-cell Lymphoma
Status: RECRUITING
Conditions: Diffuse Large B-cell Lymphoma (DLBCL)
Interventions: DRUG: Odronextamab|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone/Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SMART ERP for the Behavioral Treatment of Youth With Obsessive Compulsive Disorder (OCD)
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Phase One: Standardized Brief Intensive ERP|BEHAVIORAL: Phase Two: Flexible Patient Driven Intensive ERP|BEHAVIORAL: Follow-Up Phase: Booster Calls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Study of NT-501 Ciliary Neurotrophic Factor (CNTF) Implant for Macular Telangiectasia (MacTel)
Status: COMPLETED
Conditions: Macular Telangiectasia
Interventions: BIOLOGICAL: Ciliary neurotrophic factor (CNTF)|PROCEDURE: Surgery|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Change in Inflammatory State in Patients Undergoing Transcatheter Ablation of Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation|Marker of Inflammation|Inflammation|Arrhythmia
Interventions: DIAGNOSTIC_TEST: Markers of inflammation and fibrosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Liver-enriched Antimicrobial Peptide 2
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BIOLOGICAL: Liver-enriched antimicrobial peptide 2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Skin Blood Flow Response to Insulin Iontophoresis in Pressure Ulcers of SCI
Status: WITHDRAWN
Conditions: Spinal Cord Injury|Pressure Ulcers
Interventions: DRUG: Pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Dual Dose Escalation Study of Radiation and Nab-Paclitaxel in Patients With Unresectable and Borderline Resectable Pancreatic Cancer
Status: RECRUITING
Conditions: Locally Advanced Unresectable Pancreatic Cancer Treated With Chemoradiotherapy|Borderline Resectable Pancreatic Cancer Treated With Chemoradiotherapy
Interventions: RADIATION: Radiotherapy|DRUG: Abraxane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Pharmacist Intervention on Medication Adherence and Clinical Outcomes in Chronic Kidney Disease Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Kidney Disease
Interventions: BEHAVIORAL: Pharmacist counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Extracorporeal Biofeedback Device for Post-prostatectomy Incontinence
Status: UNKNOWN
Conditions: Prostate Neoplasm|Prostatectomy|Surgical Procedures, Robotic|Urinary Incontinence|Biofeedback|Pelvic Floor|Exercise
Interventions: DEVICE: Extracorporeal biofeedback device (Any Kegel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fasting Study of Cetirizine HCl Tablets 10 mg and Zyrtec® Tablets 10 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cetirizine HCl Tablets 10 mg|DRUG: Zyrtec® Tablets 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study Comparing the Efficacy and Tolerability of Tobrineb®/Actitob®/Bramitob® Versus TOBI®
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: tobramycin / Bramitob|DRUG: tobramycin / TOBI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency
Status: COMPLETED
Conditions: Renal Insufficiency|Congestive Heart Failure
Interventions: DRUG: tonapofylline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Quadrivalent Human Papilloma Virus (HPV) (Types 6, 11, 16, 18) Recombinant Vaccine in HIV-Infected and HIV-Negative Pre-Adolescents, Adolescents, and Young Adults
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|Human Papillomavirus- 6, 11, 16, 18|Adolescent|Papillomavirus Vaccines
Interventions: BIOLOGICAL: Gardasil|BEHAVIORAL: Survey
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Prospective Clinical Study for Laparoscopic D3 Dissection With Preservation of Left Colic Artery in Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Neoplasms
Interventions: PROCEDURE: left colic artery|PROCEDURE: High ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transitions Clinic Network: Post Incarceration Addiction Treatment, Healthcare, and Social Support
Status: RECRUITING
Conditions: Opioid Addiction
Interventions: BEHAVIORAL: Transitions Clinic Network Primary Care|BEHAVIORAL: Standard Primary Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Restrictive or Individualized Goal-Directed Fluid Replacement Strategy in Ovarian Cancer Cytoreductive Surgery
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DEVICE: EV1000(FloTrac System 4.0)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Oral PF-06651600, PF-06700841 and Placebo in Subjects With Moderate to Severe Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: PF-06651600 or Placebo|DRUG: PF-06700841 or Placebo|DRUG: PF-06700841|DRUG: PF-06651600
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Quality of Life (QoL) in Subjects With Highly Active Relapsing Multiple Sclerosis (MS) (CLARIFY MS)
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Mavenclad®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Pilot Study Investigating the Impact of ThermaCare on Flexibility, Muscle Relaxation & Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DEVICE: ThermaCare Low Back Heat Wrap
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resin Infiltration and Fluoride Varnish Lesion Arresting Efficacy on Non-cavitated Proximal Lesion
Status: UNKNOWN
Conditions: Dental Caries on Smooth Surface Limited to Enamel|Tooth Demineralization|Dental Caries|Dentistry, Operative|Dental Caries Activity Tests|Cariogram
Interventions: PROCEDURE: ICON DMG Resin Infiltration (micro-invasive approach)|PROCEDURE: ClinproTM White Varnish, 3M ESPE Fluoride Varnish (non-invasive approach)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of OTD70DERM® in Radio-dermatitis Induced by Radiotherapy-Erbitux®
Status: COMPLETED
Conditions: Head and Neck Carcinoma
Interventions: OTHER: Radiotherapy + Erbitux® + placebo|OTHER: Radiotherapy+Erbitux+OTD70DERM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Olestra Containing Foods and Weight Loss and Weight Maintenance
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: dietary education|BEHAVIORAL: dietary education and provided full fat snack foods|BEHAVIORAL: dietary education and provided fat free snack foods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Ventilation and Dexmedetomidine in Critically Ill Adults
Status: NOT_YET_RECRUITING
Conditions: Non-Invasive Ventilation
Interventions: DRUG: Dexmedetomidine|OTHER: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate TACE Sequential Tislelizumab as Adjuvant Therapy in Participants With HCC at High Risk of Recurrence After Curative Resection
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Adjuvant Therapy
Interventions: DRUG: Tislelizumab|DRUG: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Factors Involved in Dymista's Superior Clinical Efficacy to Fluticasone Propionate in the Treatment of Seasonal Allergic Rhinitis
Status: UNKNOWN
Conditions: Allergic Rhinitis
Interventions: DRUG: Placebo|DRUG: Fluticasone propionate|DRUG: Fluticasone/Azelastine nasal spray|PROCEDURE: Nasal Allergen Challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE