pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluate the Relationship Between Use of Albuterol Multidose Dry Powder Inhaler With an eModule (eMDPI) and Exacerbations in Participants With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Albuterol sulfate (ABS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trimodal (18)F-choline-PET/mpMRI/TRUS Targeted Prostate Biopsies
Status: COMPLETED
Conditions: Prostatic Neoplasm|Positron-Emission Tomography|Fluorocholine
Interventions: DEVICE: PET Scan ou TEP-TDM|DEVICE: mpMRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Myasthenia Gravis
Status: RECRUITING
Conditions: Generalized Myasthenia Gravis
Interventions: DEVICE: Whole-body Electrical Muscle Stimulation Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In-home Obesity Prevention to Reach Low-income Infants
Status: COMPLETED
Conditions: Obesity|Obesity, Childhood|Obesity; Familial
Interventions: BEHAVIORAL: Standard HVP Curriculum|BEHAVIORAL: Obesity Prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intervention Study Based on Real-world Data to Improve Quality of Life After Breast Cancer Treatment, the REBECCA-2 Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer Related Fatigue
Interventions: DRUG: REBECCA-assisted intervention 1|BEHAVIORAL: REBECCA-assisted intervention 2|OTHER: Standard follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Investigate the Effect of a Partially Hydrolysed Infant Formula With Added Synbiotics on the Development of Allergic Manifestations in Infants at High Risk of Developing Allergy
Status: WITHDRAWN
Conditions: Immunity
Interventions: OTHER: Infant Formula with added synbiotics|OTHER: Standard Infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Focal Myometrial Contractions: Impact on Cervical Assessment and Association With Voiding
Status: UNKNOWN
Conditions: Cervical Assessment|Focal Myometrial Contractions
Interventions: BEHAVIORAL: Interval bladder emptying
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigation of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Multiple Doses of Somapacitan in Subjects With Various Degrees of Impaired Renal Function Compared to Subjects With Normal Renal Function
Status: COMPLETED
Conditions: Growth Hormone Disorder|Adult Growth Hormone Deficiency|Growth Hormone Deficiency in Children
Interventions: DRUG: Somapacitan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zanubrutinib in Combination With R-CHOP (ZaR-CHOP) for Newly Diagnosed Diffuse Large B-Cell Lymphoma
Status: RECRUITING
Conditions: Diffuse Large B-Cell Lymphoma|Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma|Transformed Marginal Zone Lymphoma to Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Doxorubicin Hydrochloride|DRUG: Prednisone|BIOLOGICAL: Rituximab|DRUG: Vincristine Sulfate|DRUG: Zanubrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of OC-1 Therapy in Patients With R/R T-ALL/LL
Status: RECRUITING
Conditions: T-cell Acute Lymphoblastic Leukemia|Lymphoblastic T-Cell Lymphoma
Interventions: BIOLOGICAL: CD1a-CAR T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mobile Lymphedema Self-Care Support Program on Self-Care in Women With Breast Cancer-related Lymphedema
Status: COMPLETED
Conditions: Breast Cancer Related Lymphedema
Interventions: OTHER: Mobile Lymphedema Self-Care Support Program|OTHER: standart lymphedema education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Direct Noise Reduction in the Intensive Care Units (ICU) Using Earplugs and Noise Canceling Headphones
Status: TERMINATED
Conditions: Delirium|Sleep Fragmentation
Interventions: DEVICE: Foam Earplugs|DEVICE: Noise Canceling Headphones
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: TAP vs QL for Postoperative Analgesia After DIEP Free Flap Breast Reconstruction
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: PROCEDURE: TAP block|PROCEDURE: QL Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate The Safety, Tolerability And Pharmacokinetics Of Single Doses Of PF-04958242 In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-04958242|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Healthy Aging Through Time- Restricted Eating in Adults With Overweight/Obesity and Incipient Liver Disease: ENSATI
Status: RECRUITING
Conditions: Biological Aging
Interventions: OTHER: Unrestricted Mediterranean diet|OTHER: Energy-reduced Mediterranean diet|OTHER: Mediterranean diet with time-restricted eating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Etoposide, Oxaliplatin and Capecitabine in Advanced Hepatocellular Carcinoma (HCC)
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Etoposide|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome of Different IOLs in Patients With and Without Uveitis
Status: COMPLETED
Conditions: Uveitis|Cataract|Inflammation|Posterior Capsule Opacification
Interventions: DEVICE: Hydrophobic IOL: Vivinex (HOYA)|DEVICE: Hydrophilic IOL: INCISE (Bausch+Lomb)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Efficacy and Safety of Vanucizumab and FOLFOX With Bevacizumab and FOLFOX in Participants With Untreated Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: 5-FU|DRUG: Bevacizumab|DRUG: Folinic acid|DRUG: Oxaliplatin|DRUG: Vanucizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Multiple Daily Dosing of Oral LFF571 in Patients With Moderate Clostridium Difficile Infections
Status: COMPLETED
Conditions: Moderate Clostridium Difficile Infection
Interventions: DRUG: LFF571|DRUG: Vancomycin (POC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Crisaborole Ointment 2% in Adult Japanese Healthy Subjects and Adult Japanese Subjects With Mild To Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Healthy|Atopic Dermatitis
Interventions: DRUG: Crisaborole ointment 2%|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Polihexanide (PHMB) Eye Drops in Patients Affected by Acanthamoeba Keratitis
Status: COMPLETED
Conditions: Acanthamoeba Keratitis
Interventions: DRUG: PHMB 0.08%|DRUG: Propamidine 0.1%|DRUG: placebo|DRUG: PHMB 0.02%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Spirulina Compared to Amlodipine on Cardiac Iron Overload in Children With Beta Thalassemia
Status: COMPLETED
Conditions: Beta Thalassemia Major
Interventions: DRUG: Spirulina|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Possible Effects on the QTc Interval of CHF 4226 pMDI in Healthy Volunteers
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: CHF 4226 pMDI|DRUG: CHF 4226 pMDI|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROTOCOL 3: Role of the Renal Nerves in the Increase in EGP in Response to Glucosuria
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Dapagliflozin 10mg then Placebo Oral Tablet|DRUG: Placebo Oral Tablet then Dapagliflozin 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Color Stability of E.Max CAD Laminate Veneers Cemented With Light Cure Versus Dual Cure Amine Free Adhesive Resin Cement
Status: UNKNOWN
Conditions: Tooth Discoloration
Interventions: OTHER: E.Max CAD Laminate Veneers cemented with dual cure amine free adhesive resin cement|OTHER: E.Max CAD Laminate Veneers cemented with light cured adhesive resin cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study in COPD (Chronic Obstructive Pulmonary Disease) Subjects to Investigate Safety, Tolerability, and Pharmacokinetics of Ciprofloxacin After Single Dose Inhalations of 50 mg and 75 mg Ciprofloxacin Inhalation Powder
Status: COMPLETED
Conditions: Infection|Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Cipro Inhale (Ciprofloxacin, BAYQ3939)|DRUG: Cipro Inhale (Ciprofloxacin, BAYQ3939)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Citrulline Supplementation on the Delay of Delivery for Women Hospitalized for Pre-eclampsia (CITRUPE)
Status: COMPLETED
Conditions: Pre-eclampsia|Pregnancy
Interventions: DRUG: Citrulline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of the LuViva Advanced Cervical Scan to Identify Women at High-Risk for Cervical Neoplasia
Status: ENROLLING_BY_INVITATION
Conditions: Cervical Dysplasia
Interventions: DIAGNOSTIC_TEST: LuViva Advanced Cervical Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Watermelon and Beetroot Products on Endothelial Function
Status: COMPLETED
Conditions: Healthy Young|Older People With Cardiovascular Disease Risk
Interventions: DIETARY_SUPPLEMENT: Watermelon|DIETARY_SUPPLEMENT: Beetroot|DIETARY_SUPPLEMENT: Watermelon + beetroot|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Investigating N-3 Fatty Acids to Prevent Neonatal Tobacco-related outcomeS
Status: RECRUITING
Conditions: Preterm Labor|Tobacco Use Disorder
Interventions: DRUG: Fish Oil (Containing Omega-3 Acids)|DRUG: Olive Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Cannabidiol on the Driving Ability of Healthy Adults
Status: COMPLETED
Conditions: Driving Performance|Cognitive Impairment|Sedation Complication|Mood
Interventions: DRUG: 300 mg Cannabidiol (CBD) oil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Clinical Efficacy and Safety of Paclitaxel Polymeric Micelles for Injection in the Treatment of Patients With Taxans-resistant Pancreatic Adenocarcinoma, Cholangiocarcinoma, Lung Cancer, Gastric Cancer, Esophageal Carcinoma, or Breast Cancer
Status: RECRUITING
Conditions: Pancreatic Adenocarcinoma|Cholangiocarcinoma|Lung Cancer|Stomach Cancer|Esophageal Carcinoma|Breast Cancer
Interventions: DRUG: Paclitaxel Polymeric Micelles for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mediterranean Diet and Postprandial Lipemia
Status: COMPLETED
Conditions: Postprandial Lipemia|Type 2 Diabetes
Interventions: OTHER: Mediterranean diet and Low-Carbohydrates diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ketamine on Postoperative Clinical Outcomes
Status: TERMINATED
Conditions: Colorectal Surgery
Interventions: DRUG: Placebo|DRUG: Ketamine high-dose|DRUG: Ketamine low-dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of A neW Management Strategy for Patients With pArKinson's disEase usiNg an Innovative telemonitorING (AWAKENING)
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: DIGIPARK MONITOR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sevoflurane and Isoflurane - During Cardiopulmonary Bypass With the MECC System (Minimized Extracorporeal Circuit)
Status: COMPLETED
Conditions: Myocardial Reperfusion Injury
Interventions: DRUG: Sevoflurane|DRUG: Isoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib, Cladribine, and Rituximab in Treating Patients With Advanced Mantle Cell Lymphoma or Indolent Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Mantle Cell Lymphoma|Indolent Lymphoma|SLL
Interventions: DRUG: rituximab|DRUG: bortezomib|DRUG: cladribine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: StoMakker Mobile Application
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases|Anorectal Malformations|Spina Bifida|Ostomy
Interventions: DEVICE: StoMakker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Survival of Monocytes Collected From Patients With Atrophic AMD in Retinal Pigmented Epithelium Explants
Status: RECRUITING
Conditions: Age Related Macular Degeneration
Interventions: OTHER: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Fractionated Stereotactic Radiosurgery With Concurrent Bevacizumab for Brain Metastases: A Phase I Dose-escalation Trial
Status: UNKNOWN
Conditions: Brain Neoplasm
Interventions: RADIATION: Fractionated stereotactic radiosurgery|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Evolocumab on Chronic Total Occlusions (EVOLO-CTO)
Status: RECRUITING
Conditions: In-stent Restenosis|Major Adverse Cardiovascular Events
Interventions: DRUG: PCSK9 inhibitor|DRUG: Statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Etiological Study of Persistent Velopharyngeal Insufficiency in Children With Operated Velopalatine Cleft by Analysis of Velopharyngeal Motor Skills in Static and Dynamic MRI
Status: RECRUITING
Conditions: Velopharyngeal Insufficiency|Real Time MRI|Cleft Palate
Interventions: OTHER: real time MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Placebo-controlled Single Dose Study to Evaluate Safety and Pharmacokinetics of GMI-1271 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Adult Subjects
Interventions: DRUG: GMI-1271|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Mechanisms of Light-based Therapies for Dry Eye Disease
Status: RECRUITING
Conditions: Dry Eye Syndromes|Meibomian Gland Dysfunction
Interventions: DEVICE: Actual IPL|DEVICE: Sham IPL|DEVICE: LLLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docosahexaenoic Acid (DHA) Supplementation in High Risk Pregnancies
Status: UNKNOWN
Conditions: Inflammation|Pregnancy Related
Interventions: DIETARY_SUPPLEMENT: DHA supplement|DIETARY_SUPPLEMENT: Corn Oil: Soybean Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessing the Efficacy and Safety of Rosiglitazone Added to Standard Therapy for Hepatitis C Genotype 1 With Fatty Liver
Status: TERMINATED
Conditions: Chronic Hepatitis C Infection|Fatty Liver
Interventions: DRUG: Rosiglitazone and Pegasys/Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Zinc Supplementation for Improving Treatment Outcomes Among COVID-19 Patients in India
Status: COMPLETED
Conditions: COVID-19
Interventions: DIETARY_SUPPLEMENT: Vitamin D3 (cholecalciferol)|DIETARY_SUPPLEMENT: Zinc (zinc gluconate)|DIETARY_SUPPLEMENT: Zinc (zinc gluconate) & Vitamin D (cholecalciferol)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peer Group Regulated mCIMT Program for Adult Stroke Patients: Effects on Functional Activities
Status: COMPLETED
Conditions: Weakness of Extremities as Sequela of Stroke|Modified Constraint Induced Movement Therapy After Stroke|Upper Extremity Functional Performance After Stroke
Interventions: OTHER: Constraint-induced movement therapy: PEPS-MIT|OTHER: Bimanual manipulation exercises (PEPS-Bimanual)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telemedicine for Unhealthy Alcohol Use in Persons Living With HIV Using CETA
Status: RECRUITING
Conditions: Hiv|Alcohol Problem
Interventions: BEHAVIORAL: Alcohol Brief Intervention (BI)|BEHAVIORAL: Common Elements Treatment Approach (CETA) via Telemedicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial to Evaluate The Effect of Oral Methylprednisolone on Seizure Frequency in Children With Epilepsy
Status: UNKNOWN
Conditions: Intractable Epilepsy|Convulsive Seizures
Interventions: DRUG: methylprednisolone sodium succinate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Celiac Disease Prevention With Probiotics
Status: COMPLETED
Conditions: Celiac Disease in Children
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of α-linolenic Acid Supplementation on Hemostasis in Nondiabetic and Hypercholesterolemic Subjects
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: ALA group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of S-adenosyl-l-methionine in Treatment of Alcoholic Hepatitis With Cholestasis
Status: UNKNOWN
Conditions: Hepatitis, Alcoholic
Interventions: DRUG: Ademethionine|DRUG: Polyene Phosphatidyl choline|DRUG: Ademethionine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aliskiren Versus Ramipril on Antiproteinuric Effect in Hypertensive, Type 2 Diabetic Patients With Microalbuminuria
Status: UNKNOWN
Conditions: Hypertension|Type 2 Diabetes
Interventions: DRUG: Ramipril|DRUG: Experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Goal Management Training for Patients With Schizophrenia or High Risk for Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Neurocognitive Disorders
Interventions: BEHAVIORAL: GMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Muscle Training With Normocapnic Hyperpnea in Chronic Obstructive Pulmonary Disease (COPD)
Status: UNKNOWN
Conditions: COPD
Interventions: DEVICE: Spirotiger®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Quadrivalent Meningococcal Tetanus Protein Conjugate Vaccine in Toddlers
Status: COMPLETED
Conditions: Meningitis|Meningococcal Infection
Interventions: BIOLOGICAL: Meningococcal Polysaccharide Tetanus Protein Conjugate|BIOLOGICAL: Meningococcal Polysaccharide Tetanus Protein Conjugate|BIOLOGICAL: Meningococcal Polysaccharide Tetanus Protein Conjugate|BIOLOGICAL: Meningococcal Polysaccharide Tetanus Protein Conjugate|BIOLOGICAL: Meningococcal Polysaccharide Tetanus Protein Conjugate|DIETARY_SUPPLEMENT: Meningococcal polysaccharide group C conjugated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Dynamic Soft Tissue Mobilization in Reducing Hamstring Tightness in Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis|Muscle Tightness|Range of Motion|Dynamic Stretching
Interventions: OTHER: Dynamic soft tissue mobilization|OTHER: Proprioceptive neuromuscular facilitation stretching|OTHER: Cryotherapy|OTHER: Isometric knee strengthening excercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Gabapentin Enacarbil on Arousals, Heart Rate, Blood Pressure and PLMs in Restless Legs Syndrome
Status: UNKNOWN
Conditions: Restless Legs Syndrome
Interventions: DRUG: Gabapentin Enacarbil (GEn)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: iCare Stress Management e-Training for Dementia Family Caregivers
Status: COMPLETED
Conditions: Alzheimer's Disease|Dementia
Interventions: BEHAVIORAL: CBT-based program for dementia caregivers|BEHAVIORAL: Educational/Resources program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Metronomic Therapy in Metastatic Breast Cancer.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: bevacizumab, Paclitaxel|BIOLOGICAL: Bevacizumab, Cyclophosphamide, Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lactobacillus GG in the Prophylaxis of Ventilator Associated Pneumonia
Status: COMPLETED
Conditions: Pneumonia|Ventilator Associated Pneumonia
Interventions: DIETARY_SUPPLEMENT: Lactobacillus GG|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Personalized Fiber and Insulin Sensitivity
Status: COMPLETED
Conditions: Type 2 Diabetes|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Fermentable oligosaccharide|DIETARY_SUPPLEMENT: Personalized fiber mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Psychopharmacology of Psilocybin in Cancer Patients
Status: COMPLETED
Conditions: Depressive Symptoms|Anxiety|Cancer
Interventions: DRUG: psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Incidence of Cut-out Using Intramedullary Nails With Double Cephalic Screw vs. Unique in Pertrochanteric Fractures
Status: NOT_YET_RECRUITING
Conditions: Proximal Femoral Fractures
Interventions: DEVICE: Gamma 3 Nail (Stryker)|DEVICE: Chimaera Nail (Orthofix)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PCAR-119 Bridge Immunotherapy Prior to Stem Cell Transplant in Treating Patients With CD19 Positive Leukemia and Lymphoma
Status: UNKNOWN
Conditions: Acute Lymphocytic Leukemia|Chronic Lymphocytic Leukemia|Follicular Lymphoma|Mantle Cell Lymphoma|B-cell Prolymphocytic Leukemia|Diffuse Large Cell Lymphoma
Interventions: BIOLOGICAL: anti-CD19 CAR-NK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ventilation and Perfusion in the Respiratory System
Status: ENROLLING_BY_INVITATION
Conditions: Respiratory Failure|Respiratory Distress Syndrome, Adult|Critical Illness|Pulmonary Disease|Ventilator-Induced Lung Injury
Interventions: DEVICE: Electrical Impedance tomography|OTHER: Lung mechanics and gas exchange
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Positive Suggestions Via MP3 Messages
Status: RECRUITING
Conditions: Post Intensive Care Unit Syndrome|Psychological Trauma|Anxiety|Depression|PTSD
Interventions: OTHER: Psychological Support Based on Positive Suggestion delivered via pre-recorded MP3 message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Platinum-Cetuximab Combined With Docetaxel or With 5FU in Patients With Recurrent/Metastatic HNSCC
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Cisplatin|DRUG: 5-Fluorouracile|DRUG: Docetaxel|DRUG: Cetuximab|DRUG: granulocyte colony-stimulating factor (G-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Explosive Synchronization of Brain Network Activity in Chronic Pain
Status: RECRUITING
Conditions: Fibromyalgia|Healthy Volunteers
Interventions: DIAGNOSTIC_TEST: EEG|DIAGNOSTIC_TEST: Neuroimaging EEG/fMRI|DEVICE: HD-tDCS treatments|DEVICE: Sham HD-tDCS treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incobotulinum Toxin A for Sialorrhea in Parkinson's Disease (PD)/Parkinsonism and Amyotrophic Lateral Sclerosis (ALS)
Status: WITHDRAWN
Conditions: Parkinson Disease|Amyotrophic Lateral Sclerosis
Interventions: DRUG: Incobotulinum Toxin A|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Patients With Type 2 Diabetes
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY2608204|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic and Safety Study of Single and Multiple Doses of Rabreprazole in Pediatric Patients With Gastroesophageal Reflux Disease (GERD) 1 to 11 Years Old, Inclusive
Status: COMPLETED
Conditions: GERD
Interventions: DRUG: Rabeprazole sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quadriceps Strengthening at Different Angles in Patellofemoral Pain
Status: NOT_YET_RECRUITING
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Protected Range Quadriceps Strengthening group|OTHER: Patient-Guided Range Quadriceps Strengthening group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Nicotine Pharmacokinetics and Smoking Behaviour Study Examining Cigarette Ingredients
Status: COMPLETED
Conditions: Healthy Volunteers|Smoking
Interventions: OTHER: Reference cigarette|OTHER: Cigarette with carob bean extract|OTHER: Cigarette with cocoa powder|OTHER: Cigarette with fenugreek extract|OTHER: Cigarette with fig juice|OTHER: Cigarette with glycerol|OTHER: Cigarette with guaiacol|OTHER: Cigarette with liquorice extract powder|OTHER: Cigarette plus I-menthol|OTHER: Cigarette with propylene glycol|OTHER: Cigarette with sorbitol|OTHER: Cigarette with multiple ingredients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Single Centre, Phase I, Double-blind, Randomised, Placebo-controlled Study to Investigate the Safety, Tolerability, Pharmacokinetic Profile and Effects on EEG of Single Rising Oral Doses of BIA 2-093
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: BIA 2-093|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amphotericin B Cholesteryl Sulfate Complex for Injection(ABCD) in the Treatment of Invasive Candidiasis and Invasive Aspergillosis
Status: UNKNOWN
Conditions: Invasive Candidiasis|Invasive Aspergillosis
Interventions: DRUG: Amphotericin B cholesteryl sulfate complex for injection(ABCD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Antenatal Randomised Study to CharactErise Key Roles of TetrahydroFOLate in HyperTensive Pregnancies
Status: UNKNOWN
Conditions: Pre-Eclampsia|Pregnancy Induced Hypertension|Pregnancy Related
Interventions: DIETARY_SUPPLEMENT: Arcofolin® 5-Methyltetrahydrofolate|DIETARY_SUPPLEMENT: Arcofolin® Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Dexamethasone on Sugammadex Reversal
Status: COMPLETED
Conditions: Incomplete Reversal of Neuromuscular Block
Interventions: DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Efficacy and Safety With the Transdermal Contraceptive System Versus Triphasil.
Status: COMPLETED
Conditions: Contraception|Female Contraception
Interventions: DRUG: norelgestromin + ethinyl estradiol; triphasil.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cluster Headache Cortivazol Injection (CHCI)
Status: COMPLETED
Conditions: Cluster Headache
Interventions: DRUG: ALTIM, cortivazol injections|DRUG: PROAMP, subcutaneous serum physiological saline|DRUG: Verapamil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Hyper-CVAD In Combination With Venetoclax In Pediatric Patients With Relapsed or Refractory Acute Leukemias That Are of the Lymphoid Lineage Including Bi-Phenotypic or Undifferentiated Leukemias
Status: NOT_YET_RECRUITING
Conditions: Refractory Acute Leukemia|Relapsed Acute Leukemia|Undifferentiated Leukemia|Bi-Phenotypic Leukemia
Interventions: DRUG: Venetoclax|DRUG: Hyper-CVAD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dapagliflozin on Ultrafiltration Among Peritoneal Dialysis Patients
Status: COMPLETED
Conditions: Peritoneal Dialysis Complication|Ultrafiltration Failure
Interventions: DRUG: Dapagliflozin 10Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunoblot, Chemiluminescence and ImmunoCap Allergen Specific IgE Evaluation of in Allergic Rhinitis Patients
Status: COMPLETED
Conditions: Diagnoses Disease
Interventions: DIAGNOSTIC_TEST: Sensitization to House dust mites
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A 6-week, Study of MG01CI Low Dose and High Dose Compared With Placebo in Adults and Adolescents With Fragile X Syndrome
Status: COMPLETED
Conditions: Fragile X Syndrome
Interventions: DRUG: MG01CI extended-release tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Local Anesthetic Automated Intermittent Administration vs. Continuous Infusion Via Femoral Nerve Block.
Status: COMPLETED
Conditions: Postoperative Pain|Postoperative Complications
Interventions: DRUG: Ropivacaine Hcl 0.2% Inj Bag 200Ml (PIB mode)|DRUG: Ropivacaine Hcl 0.2% Inj Bag 200Ml (CI mode)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neo-adjuvant Treatment With Temozolomide and Bevacizumab Previous to Temozolomide Plus Radiation Plus Bevacizumab Therapy in Unresectable Glioblastoma
Status: COMPLETED
Conditions: Glioblastomas
Interventions: DRUG: Temozolomide|DRUG: Bevacizumab|RADIATION: Standard radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diets With a Spectrum of Fat Intake for Preventing Obesity: A Randomized Controlled-feeding Trial
Status: COMPLETED
Conditions: Healthy
Interventions: BEHAVIORAL: low-fat diet|BEHAVIORAL: moderate-fat diet|BEHAVIORAL: high-fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of IVMED-85 on Pediatric Myopia
Status: NOT_YET_RECRUITING
Conditions: Myopia, Progressive
Interventions: DRUG: IVMED 85|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of Angiotensin Receptor Antagonist on Prohibiting Cardiovascular Events on Hemodialysis Patients
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: candesartan or valsartan or losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Left Ventricular Unloading to Improve Outcome in Cardiogenic Shock Patients on VA-ECMO
Status: RECRUITING
Conditions: Cardiogenic Shock
Interventions: DEVICE: Impella|DEVICE: VA-ECMO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of CEA-targeted CAR-T for CEA-positive Advanced Malignant Solid Tumors
Status: RECRUITING
Conditions: Gastric Cancer|Colon Cancer|Rectal Cancer|Esophageal Cancer|Pancreatic Cancer
Interventions: BIOLOGICAL: CEA-targeted CAR-T cells|BIOLOGICAL: CEA-targeted CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peer Conselling Infant Feeding Education Program
Status: COMPLETED
Conditions: Infant Malnutrition|Pregnant Women|Lactating Mother|Breastfeeding|Infant Nutrition|Stunting
Interventions: BEHAVIORAL: Peer counseling on infant feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Surgical or Medical Treatment
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Pediatric Obesity|Bariatric Surgery Candidate
Interventions: PROCEDURE: Advanced Medical Therapy and Bariatric Surgery|DRUG: Advanced Medical Therapy|PROCEDURE: Bariatric Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Misoprostol Versus Uterine Striating by Bladder Filling for Pain Relief During Office Hysteroscopy
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Misoprostol|OTHER: Bladder Filling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Thoracal Epidural Steroid and Local Anesthetic Injection
Status: COMPLETED
Conditions: Chronic Postoperative Pain|Chest Pain|Back Pain
Interventions: DRUG: thoracic interlaminar epidural injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Diaphragm Pacing System (DPS) In Participants With Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: DEVICE: NeuRx® Diaphragm Pacing System™ (DPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Incidence of Severe COVID-19 Infection in Patients With CLL or B-NHL Who Received Pre-exposure Prophylaxis With Tixagevimab and Cilgavimab in Italy.
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Indolent B-Cell Non-Hodgkin Lymphoma|COVID-19
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Elderly Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic (MD) Syndrome With Laromustine and Infusional Cytarabine
Status: TERMINATED
Conditions: Acute Myeloid Leukemia (AML)|Myelodysplastic Syndrome (MDS)
Interventions: DRUG: Laromustine (VNP40101M) and Ara-C
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation and Cohort Expansion Study of Niraparib and Dostarlimab in Pediatric Participants With Solid Tumors (SCOOP)
Status: SUSPENDED
Conditions: Neoplasms
Interventions: DRUG: Niraparib|DRUG: Dostarlimab|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arrhythmia in Hemodialysis Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Arrythmia, Cardiac|Sudden Cardiac Death|Hemodialysis
Interventions: DEVICE: Reveal LINQ insertable cardiac monitoring system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: To Compare the Pharmacokinetics and Pharmacodynamics of HR20014, INS068 and INS062 After Single Subcutaneous Injection in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: INS062 injection、INS068 injection、HR20014 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: We Compared the Covid-19 Acute Respiratory Distress Syndrome (ARDS) Patients Who Applied Prone Positioning for16-24 Hours vs 24-48 Hours
Status: COMPLETED
Conditions: Morality|Oxygenation Indices|Hypoxia
Interventions: OTHER: prone positioning
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ketamine Effect on Isoflurane Anesthesia
Status: COMPLETED
Conditions: Post-anesthesia Recovery
Interventions: DRUG: ketamine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chemotherapy and Radiation Therapy After Surgery in Treating Children With Newly Diagnosed Astrocytoma, Glioblastoma Multiforme, Gliosarcoma, or Diffuse Intrinsic Pontine Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: temozolomide|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Multicenter Post Approval Study of the LPS-Flex Mobile Bearing Knee
Status: COMPLETED
Conditions: Osteoarthritis|Traumatic Arthritis|Avascular Necrosis of the Femoral Condyle|Moderate Varus|Valgus|Flexion Deformities
Interventions: DEVICE: NexGen LPS-Flex Mobile Bearing Knee
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-dose Dexamethasone Combining Thalidomide Versus Dexamethasone Mono-therapy for Management of Newly-diagnosed ITP
Status: WITHDRAWN
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Dexamethasone|DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATRA, Celecoxib, and Itraconazole as Maintenance
Status: COMPLETED
Conditions: Relapsed Multiple Myeloma
Interventions: DRUG: ATRA|DRUG: Celecoxib|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACE Inhibitors or ARBs Discontinuation in Context of COVID-19 Pandemic
Status: TERMINATED
Conditions: History of Cardiovascular Disease Treated With RAS Blockers and With SARS-CoV-2 Infection
Interventions: DRUG: 1: discontinuation of RAS blocker therapy|DRUG: 2: continuation of RAS blocker therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neotrofin for Treatment of Chemotherapy-Induced Peripheral Neuropathy
Status: COMPLETED
Conditions: Peripheral Nervous System Diseases|Chemotherapy-Induced Peripheral Neuropathy
Interventions: DRUG: leteprinim potassium (Neotrofin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Agave Syrup, Placebo, and No Treatment on Nocturnal Cough and Sleep Quality for Coughing Infants/Toddlers and Their Parents
Status: COMPLETED
Conditions: Cough
Interventions: DIETARY_SUPPLEMENT: Agave Syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Repeated Painful Procedures in Preterm Neonates on Short Term Neurobehavioural Outcome
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: 24% Sucrose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Pharmacokinetic Interaction and the Safety of Inhaled CHF5259 and CHF6001
Status: COMPLETED
Conditions: Copd
Interventions: DRUG: CHF5259 and CHF6001|DRUG: CHF5259 + placebo|DRUG: CHF6001 + placebo|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Straight Versus Coiled Peritoneal Dialysis Catheter for Peritoneal Dialysis Patients
Status: COMPLETED
Conditions: End-stage Renal Disease|Renal Failure
Interventions: DEVICE: Tenckhoff catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Efprezimod Alfa (CD24Fc, MK-7110) When Administered Intravenously in Healthy Adult Subjects (MK-7110-001)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: Efprezimod alfa|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER