pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparing Mescaline Sodium Enteric-coated Tablets vs Morte-mescaline in the Treatment of Adult Lupus Nephritis
Status: NOT_YET_RECRUITING
Conditions: Lupus Nephritis
Interventions: DRUG: Mescaline sodium enteric-coated tablets|DRUG: Morte-mescaline|DRUG: Glucocorticoids
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Somatocognitive Therapy in Treatment of Provoked (Localized) Vestibulodynia - Randomized Clinical Trial (ProLoVe Study)
Status: RECRUITING
Conditions: Vulvodynia|Vestibulodynia
Interventions: OTHER: Somatocognitive physiotherapy|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment With Zoledronate Subsequent to Denosumab in Osteoporosis 2 (ZOLARMAB2)
Status: RECRUITING
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: Zoledronate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Laser Peripheral Iridotomy Plus Laser Peripheral Iridoplasty for Primary Angle Closure
Status: UNKNOWN
Conditions: Glaucoma, Angle-Closure
Interventions: DEVICE: neodymium:yttrium-aluminum- garnet laser|DEVICE: frequency-doubled Q-switched neodymium:yttrium-aluminum-garnet 532-nm laser|DRUG: Pilocarpine|PROCEDURE: LPIP plus LPI|DRUG: Proparacaine|PROCEDURE: LPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pregabalin, Celecoxib, Total Knee Arthroplasty and Intrathecal Morphine
Status: COMPLETED
Conditions: Postoperative Pain Management|Total Knee Arthroplasty
Interventions: DRUG: Pregabalin|DRUG: Celecoxib|DRUG: Pregabalin with celecoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pazopanib Hydrochloride in Treating Patients With Metastatic Melanoma That Cannot be Removed by Surgery
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage IV Cutaneous Melanoma AJCC v6 and v7
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Pazopanib Hydrochloride|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Usage of Acyclovir for Suppression of HIV-1 and HSV-2 Coinfected Persons in Cameroon
Status: COMPLETED
Conditions: HIV-1 and HSV-2 Coinfection|HIV Infections
Interventions: DRUG: Acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics & Pharmacodynamics of Diethylcarbamazine (DEC)+ Albendazole (ALB) + Ivermectin (IVE)
Status: COMPLETED
Conditions: Wuchereria Bancrofti Infection
Interventions: DRUG: Ivermectin, Diethylcarbamazine Albendazole (IDA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: TRANSFORM-HF: ToRsemide compArisoN With furoSemide FORManagement of Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Torsemide|DRUG: Furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DAILIES TOTAL1® Soft Contact Lenses - Post-Market Clinical Follow-up Study
Status: NOT_YET_RECRUITING
Conditions: Myopia|Hyperopia|Presbyopia|Astigmatism
Interventions: DEVICE: Delefilcon A spherical soft contact lenses|DEVICE: Delefilcon A toric soft contact lenses|DEVICE: Delefilcon A multifocal soft contact lenses
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial for Evaluation of Adequate Dose and Safety of DW-3102 in Hypercholesterolemia Patients
Status: UNKNOWN
Conditions: Hypercholesterolemia
Interventions: DRUG: DW-3102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improvement of Perioperative Care of Elderly Patients
Status: COMPLETED
Conditions: Perioperative Care
Interventions: BEHAVIORAL: Systematic inclusion of family members|BEHAVIORAL: Preoperative information|BEHAVIORAL: Physical and breathing exercises|DIETARY_SUPPLEMENT: Dietary supplements|OTHER: Evaluation of long-term medication|PROCEDURE: Regional anesthesia|OTHER: Personal aids|DEVICE: Temperature management|DEVICE: Neurmonitoring|PROCEDURE: Pain catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Plasmatic Concentrations of Propofol and Remifentanil in Obese and Non Obese Patients.
Status: COMPLETED
Conditions: General Anesthesia|Obesity
Interventions: DRUG: Pharmacokinetic of propofol and remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: TAB08 in Patients With Systemic Lupus Erythematosus (SLE), Not Adequately Controlled With Current Treatment
Status: TERMINATED
Conditions: Lupus Erythematosus, Systemic
Interventions: DRUG: TAB08|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Protein Intake on Preterm Infant Body Composition
Status: COMPLETED
Conditions: Premature; Infant, Light-for-dates
Interventions: DIETARY_SUPPLEMENT: Protein supplementation|DIETARY_SUPPLEMENT: Standard fortification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Mechanisms of Action of Dimethyl Fumarate (Tecfidera) in Relapsing MS
Status: WITHDRAWN
Conditions: Multiple Sclerosis|Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Dimethyl Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Safety and Efficacy of Two Antiviral Treatments in the Treatment of Recurrent Herpes Simplex Labialis
Status: COMPLETED
Conditions: Herpes Labialis
Interventions: DRUG: Acyclovir 5 percent (Perrigo)|DRUG: Acyclovir 5 percent (Reference)|DRUG: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy, Hormone Therapy, and Radiation Therapy in Treating Patients With Locally Advanced Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: carboplatin|DRUG: estramustine|DRUG: paclitaxel|RADIATION: radiation therapy|DRUG: leuprolide or goserelin acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient-Reported Outcome Measures in Cardiac Rehabilitation: Impact on Health Care
Status: TERMINATED
Conditions: Quality of Life|Cardiac Rehabilitation|Patient-Reported Outcome Measures|Rehabilitation Exercise
Interventions: OTHER: Cardiac rehabilitation program (PROMs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Framing on Medication Beliefs, Intentions to Take Medication, Adherence, and Asthma Control
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: Negatively Framed text messages|BEHAVIORAL: Positively Framed text messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Postprandial Glucose Levels, Gut Microbiota and Supplementation With Functional Foods in Adults
Status: RECRUITING
Conditions: Healthy|Nutritional and Metabolic Diseases
Interventions: DIETARY_SUPPLEMENT: Dietary Supplement: A package containing a mix of functional foods
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Solifenacin and Mirabegron on the Tamsulosin Hydrochloride (HCl) Concentrations in Blood in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Subjects|Pharmacokinetics|Drug-Drug Interaction (DDI)
Interventions: DRUG: Mirabegron|DRUG: Solifenacin succinate|DRUG: Tamsulosin HCl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A First-in-Human Study Evaluating AGA2115 in Adult Healthy Volunteers
Status: RECRUITING
Conditions: Osteogenesis Imperfecta
Interventions: DRUG: AGA2115|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: This Research Study Examines the Effects of Cannabidiol-infused Candy on Reducing the Bacteria Causing Tooth Decay, When Comparing it to a Sugar Free Candy on Adults.
Status: COMPLETED
Conditions: Tooth Decay
Interventions: DIETARY_SUPPLEMENT: CBD infused candy|DIETARY_SUPPLEMENT: Sugar free Candy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: TMS + Exposure Therapy for Pediatric OCD
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Transcranial Magnetic Stimulation: intermittent theta burst to dorsolateral prefrontal cortex|BEHAVIORAL: Exposure with Response Prevention|DEVICE: Transcranial Magnetic Stimulation: Sham|DEVICE: Transcranial Magnetic Stimulation: continuous theta burst to pre supplementary motor area
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of the Tool: Evaluation of Specific Care in an Ecological Environment for Patients Suffering From Schizophrenia-like Disorders
Status: RECRUITING
Conditions: Patients With Schizophrenia-like Disorders
Interventions: OTHER: ESSME questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Gentamicin Bladder Instillations to Prevent Urinary Tract Infections in Patients With Spinal Cord Injury
Status: COMPLETED
Conditions: Urinary Tract Infections|Spinal Cord Injuries|Spinal Cord Diseases|Neurogenic Bladder
Interventions: DRUG: Gentamicin Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Open-label Study on the Clinical Efficacy of tDCS Intervention in PD
Status: RECRUITING
Conditions: Transcranial Direct Current Stimulation|Parkinson Disease|Primary Left Motor Cortex
Interventions: BEHAVIORAL: transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Stress and Anxiety in MCI/Mild ADRD
Status: RECRUITING
Conditions: Anxiety|Mild Cognitive Impairment|Alzheimer Disease|Dementia
Interventions: BEHAVIORAL: Computerized Anxiety Sensitivity Treatment|BEHAVIORAL: Health Education Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: WhatsApp Intervention to Assess the Effect of Messages in Adherence to Antiretrovirals in Young People With HIV in Peru
Status: RECRUITING
Conditions: HIV
Interventions: BEHAVIORAL: Self-designed messages|BEHAVIORAL: Standardized messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: HBV-associated Liver Transplant(LT) Patients by IV Injecting GC1102
Status: UNKNOWN
Conditions: Hepatitis B Infection
Interventions: BIOLOGICAL: GC1102 80,000 IU|BIOLOGICAL: GC1102 100,000 IU|BIOLOGICAL: I.V HBIG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Controlled Low Central Venous Pressure Combined With Hilar Block in Laparoscopic Hepatectomy
Status: UNKNOWN
Conditions: Laparoscopic Hepatectomy
Interventions: PROCEDURE: controlled low central venous pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating Perceived Fitness to Drive While Intoxicated
Status: COMPLETED
Conditions: Alcohol Drinking|Alcohol Intoxication|Perception, Self|Drinking, Alcohol|Driving Under the Influence|Drinking Behavior
Interventions: BEHAVIORAL: Participants Shown their Breath Alcohol Content Measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer
Interventions: DRUG: TTX-080|DRUG: TTX-080|DRUG: pembrolizumab|DRUG: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety, Reactogenicity and Immunogenicity of GlaxoSmithKline's (GSK)Respiratory Syncytial Virus (RSV)Maternal Unadjuvanted Vaccine in Healthy Pregnant Women (Aged 18 to 40 Years) and Their Infants
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSV MAT 60 µg|BIOLOGICAL: RSV MAT 120 µg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Molecular Services and EMR-Lab Integration Application (ELIA) for Reducing Healthcare Disparities in Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Advanced Cancer|Solid Tumor, Adult|Myeloid Malignancy
Interventions: COMBINATION_PRODUCT: Comprehensive Genomic Profile testing; ELIA software; Molecular Genetic Pathologist consultation|DIAGNOSTIC_TEST: limited genetic testing or no testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Postoperative Hypofractionated Intensity-modulated Radiation Therapy With Concurrent Chemotherapy in Cervical Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervix Cancer|Radiotherapy, Adjuvant|Radiotherapy, Intensity-Modulated|Hypofractionated Dose|Chemotherapy, Concurrent
Interventions: OTHER: POHIM-CCRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS as a Probe of Episodic Memory Neurocircuitry in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DEVICE: 1 Hz rTMS Stimulation|DEVICE: Sham rTMS Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EAP 177Lu-DOTA0-Tyr3-Octreotate for Inoperable, SSR+, NETs, Progressive Under SSA Tx
Status: APPROVED_FOR_MARKETING
Conditions: Neuroendocrine Tumors
Interventions: DRUG: 177Lu-DOTA0-Tyr3-Octreotate
Study Type: EXPANDED_ACCESS
Clinical trial: An Open-Label, Phase 1 Clinical Study to Evaluate the Safety and Tolerability of Subcutaneous Elamipretide in Subjects With Intermediate Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: Elamipretide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detrusor Contraction During the Ice-water-test
Status: COMPLETED
Conditions: Urinary Bladder, Neurogenic|Neuropathic Bladder
Interventions: PROCEDURE: Ice-water-test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluate the Effect of Dietary Supplement Combined Exercise Among Patients With Sarcopenia Comorbid With Lung Disease
Status: RECRUITING
Conditions: Sarcopenia|COPD|ILD
Interventions: DIETARY_SUPPLEMENT: Sarcojoint®|BEHAVIORAL: supervised exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Insulin Pump in Prevention of Low Glucose Events in Adults With Type 1 Diabetes at Risk of Severe Hypoglycemia
Status: COMPLETED
Conditions: Diabetes, Type 1
Interventions: DEVICE: Minimed 640G with smartguard activated|DEVICE: Minimed 640G with smartguard off
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Ropivacaine With or Without Fentanyl in Spinal Anaesthesia for Lower Limb Surgeries
Status: UNKNOWN
Conditions: Leg Injury|Arthroplasty, Replacement, Knee
Interventions: DRUG: Ropivacaine 0.75% Injectable Solution|DRUG: Fentanyl Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interactive Rehabilitation for Adults With Unilateral Vestibular Weakness
Status: COMPLETED
Conditions: Dizziness|Equilibrium; Disorder, Labyrinth|Inner Ear Injury
Interventions: DEVICE: Vestibular rehabilitation with dynamic posturography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Study for Patients With Heart Disease
Status: COMPLETED
Conditions: Chest Pain|Myocardial Ischemia|Heart Disease|Coronary Arterial Disease (CAD)|Angina
Interventions: GENETIC: Cell Therapy - Autologous CD34 Positive Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: 5-Fluorouracil Followed by Interferon-alfa-2b in Previously-treated Metastatic Gastrointestinal, Kidney, or Lung Cancer
Status: COMPLETED
Conditions: Gastrointestinal Cancer Metastatic|Renal Cell Cancer Metastatic|Non Small Cell Lung Cancer Metastatic
Interventions: DRUG: 5-Fluorouracil and Interferon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Dietary Education Trial in Carbohydrate Counting (DIET-CARB Study in Type 1 Diabetes
Status: COMPLETED
Conditions: Type1diabetes|Type1 Diabetes Mellitus|Glucose Metabolism Disorders
Interventions: BEHAVIORAL: BCC intervention|BEHAVIORAL: ABC-ACC intervention|BEHAVIORAL: Standard dietary education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Vit-D Supplementation on BioNTech, Pfizer Vaccine Side Effect and Immunoglobulin G Response
Status: COMPLETED
Conditions: COVID-19 Respiratory Infection
Interventions: COMBINATION_PRODUCT: Vitamin-D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: AMENDTM Mitral Valve Repair System, Annuloplasty Ring Applied in a Transcatheter Method
Status: COMPLETED
Conditions: Mitral Regurgitation
Interventions: DEVICE: AMEND Mitral Valve Repair System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prediction of Major Bleeding in ELBW-infants (<1000g) by Sequential Coagulation Monitoring
Status: COMPLETED
Conditions: Intraventricular Haemorrhage|Pulmonary Haemorrhage
Interventions: DEVICE: Coaguchek
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Anticipatory Muscle Control and Effect of Stabilizing Exercises in Patients With Subacute and Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: BEHAVIORAL: Isolated Transversus abdominis (TrA) exercise|BEHAVIORAL: sling exercise|BEHAVIORAL: group exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Dose of Propofol for Induction of Deep Sedation for Brain MRI Scanning in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Pharyngeal Exercise (Plus Protein)
Status: RECRUITING
Conditions: Pre-Frail Older Adults
Interventions: BEHAVIORAL: Pharyngeal Swallowing Exercises|DIETARY_SUPPLEMENT: Protein Supplementation|DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tissue Pharmacokinetics of Intraoperative Gemcitabine in Resectable Adenocarcinoma of the Pancreas
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine|DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Protocols in the Treatment of Upper Limb Dysfunctions of Patients With Stroke.
Status: COMPLETED
Conditions: Cerebral Vascular Accident
Interventions: OTHER: intermittent theta burst stimulation|OTHER: continuous theta burst stimulation|OTHER: sham theta burst stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Focused Power Ultrasound Mediated Inferior Perirenal Adipose Tissue Modification Therapy for Non-Alcoholic Fatty Liver Disease (PARADISE-NAFLD)
Status: RECRUITING
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DEVICE: focused power ultrasound mediated inferior perirenal adipose tissue modification|DEVICE: sham-control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Metabolic Enzymes and Transporter Gene Polymorphisms on the Pharmacokinetics and Metabolism of Oral Abiraterone Acetate in Healthy Chinese Adults
Status: UNKNOWN
Conditions: Abiraterone Acetate|Gene Polymorphism|Pharmacokinetic|Metabolic Analysis|Plasma Concentration
Interventions: DRUG: Abiraterone acetate tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ertugliflozin in Chronic Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: DRUG: Ertugliflozin|DRUG: Metolazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnosis of Gastritis, H. Pylori Infection and Atrophic Gastritis in Dyspeptic Patients
Status: COMPLETED
Conditions: Gastritis, Atrophic|Helicobacter Pylori Infection|Intestinal Metaplasia|Gastritis
Interventions: DIAGNOSTIC_TEST: High-Definition white light endoscopy.|DIAGNOSTIC_TEST: High-definition magnification with digital chromoendoscopy.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Heavy Alcohol Consumption on Farnesoid X Receptor (FXR) Signaling
Status: COMPLETED
Conditions: Alcohol Consumption
Interventions: DRUG: Placebo|DRUG: 10 mg Obeticholic Acid (OCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Primary Hyperparathyroidism: Does a Systematic Treatment Improve the Calcium and Bone Metabolism After Surgery?
Status: UNKNOWN
Conditions: Primary Hyperparathyroidism|Bone Metabolism
Interventions: DRUG: Calcium and vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Blind Study to Evaluate the Safety, Tolerability and Explore the Efficacy of 8.0 mg ASM8 Inhaled Daily for 14 Days in Severe Asthma
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: ASM8
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of the Relative Oral Bioavailability of AL-3778 Tablets and Drug Interaction With Entecavir or Tenofovir Disoproxil Fumarate in Healthy Volunteers
Status: TERMINATED
Conditions: Hepatitis B|Chronic Hepatitis B|Viral Hepatitis B
Interventions: DRUG: AL-3778|DRUG: Entecavir|DRUG: Tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daily Magnesium-treatment of Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: COPD
Interventions: DIETARY_SUPPLEMENT: Magnesium supplement (magnesium hydroxide/ -oxide)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Gastrointestinal Transit Pre and Pos Treatment With Non Selective Betablocker in a Population of Cirrhotics
Status: UNKNOWN
Conditions: Liver Cirrhosis
Interventions: DRUG: non selective beta blocker
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Evaluation of BD NEXT Pen Needle
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Diabetes Mellitus, Type 1
Interventions: DEVICE: BD NEXT 31G x 5 mm pen needle|DEVICE: BD NEXT 31G x 8mm pen needle|DEVICE: BD NEXT 32G x 4mm pen needle
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics and Safety Study of Tapentadol for Postsurgical Pain in Children and Adolescents
Status: COMPLETED
Conditions: Pain, Postoperative|Postoperative Pain
Interventions: DRUG: Tapentadol (OS) Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Gluten-Casein-free Diet in Children With Autism: A Clinical Results of the Ophthalmic and Behavioral Manifestations
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Ophthalmic Abnormalities
Interventions: BEHAVIORAL: Gluten Free Casein Free Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Electroacupuncture to Relieve Itching Degree in Patients With Chronic Atopic Eczema
Status: NOT_YET_RECRUITING
Conditions: Chronic Lichenified Atopic Dermatitis
Interventions: DEVICE: electroacupunture|DEVICE: sham electroacupuncture|DEVICE: sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Kinesiology Taping Versus Taping in the Treatment of Plantar Fasciitis
Status: COMPLETED
Conditions: Plantar Fasciitis
Interventions: OTHER: kinesiology taping|OTHER: taping or Low-dye taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immuno-Oncology Drugs GLS-012 Alone & in Combination GLS-010 Treating With Advanced Patients Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: GLS-012|DRUG: GLS-010
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Pamrevlumab (FG-3019), in Non-Ambulatory Participants With Duchenne Muscular Dystrophy (DMD)
Status: TERMINATED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Pamrevlumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effects of TRV120027 in Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: TRV120027|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Canine Fossa Trephination in the Severely Diseased Maxillary Sinus
Status: WITHDRAWN
Conditions: Disorder of Maxillary Sinus|Aspirin-sensitive Asthma With Nasal Polyps|Rhinosinusitis
Interventions: PROCEDURE: Canine fossa trephine technique|PROCEDURE: Standard Endoscopic Sinus Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Decreasing Risk of Psychosis by Sulforaphane (DROPS Trial)
Status: RECRUITING
Conditions: Clinical High Risk Syndrome of Psychosis
Interventions: DIETARY_SUPPLEMENT: Sulforaphane|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multiple Dose Study In Cancer Patients: Safety and Tolerability of BMS-754807 in Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Neoplasms|Solid Tumors|Metastases
Interventions: DRUG: BMS-754807
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study for Elective Cardioversion of Atrial Fibrillation at Home
Status: ENROLLING_BY_INVITATION
Conditions: Emergency Medical Services|Electric Countershock
Interventions: PROCEDURE: Duble current electro cardioversion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Best Dosage and Timing of Polyethylene Glycol for Bowel Preparation Before Capsule Endoscopy
Status: COMPLETED
Conditions: Small Bowel Disease
Interventions: DRUG: polyethylene glycol|DEVICE: capsule endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation Of Microneedling Alone vs Microneedling Along With Hyaluronic Acid In Thin Gingival Phenotype
Status: RECRUITING
Conditions: Thin-gingiva
Interventions: PROCEDURE: microneedling and hyaluronic acid for increasing gingival thickness in thin gingival phenotype|PROCEDURE: microneedling for increasing gingival thickness in thin gingival phenotype
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Teriflunomide Concentration in Serum and Cerebrospinal Fluid From Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Pharmacokinetics
Interventions: DRUG: Teriflunomide 14 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LPB Combined With QLB Using Single-needle Technique (LPQLB-SNT) for Hip Arthroplasty
Status: RECRUITING
Conditions: Hip Osteoarthritis|Anesthesia, Local|Hip Fractures|Osteonecrosis of Femoral Head
Interventions: PROCEDURE: L3 LPB|PROCEDURE: L4 LPB|PROCEDURE: T12 block|PROCEDURE: L3 QLB|DRUG: 0.375%ropivacaine 25 ml (Raropin)|DRUG: 0.375%ropivacaine 40 ml (Raropin)|PROCEDURE: General anesthesia with tracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Consequences of Post Stroke Polysomnographic Abnormalities on Functionnal Recovery and Survival After an Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke|Cerebral Infarct|Sleep Apnea|Periodic Limb Movement Disorder
Interventions: OTHER: Sleep recording (already done)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Doxorubicin-associated Cardiac Remodeling Followed by CMR in Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer Female|Doxorubicin Induced Cardiomyopathy
Interventions: DRUG: Doxorubicin|DEVICE: Achieva, Philips Medical Systems (3T magnet)|DRUG: Gadoterate Meglumine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Safety and Efficacy of Ipatasertib in Combination With Atezolizumab and Paclitaxel or Nab-Paclitaxel in Participants With Locally Advanced or Metastatic Triple-Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Ipatasertib|DRUG: Paclitaxel|DRUG: Atezolizumab|DRUG: Nab-Paclitaxel|DRUG: AC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Azacitidine Plus Pevonedistat Versus Azacitidine in Patients With Acute Myeloid Leukemia Not Eligible for Standard Chemotherapy
Status: UNKNOWN
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Pevonedistat|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Lemborexant-Alcohol Interaction in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Lemborexant|DRUG: Alcohol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: a Study to Evaluate the Safety and Efficacy of D-1553 Combined With IN10018 in KRAS G12C Mutant Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: D1553|DRUG: IN10018（Ifebemtinib）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Therapeutic Ultrasound Versus Shockwave Therapy in Medial Tibial Stress Syndrome in Recreational Runners
Status: COMPLETED
Conditions: Medial Tibial Stress Syndrome
Interventions: OTHER: baseline physical therapy treatment along with shockwave therapy|OTHER: baseline physical therapy treatment along with therapeutic ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of TS-142 in Patients With Insomnia
Status: COMPLETED
Conditions: Patients With Insomnia
Interventions: DRUG: TS-142 5 mg|DRUG: TS-142 10 mg|DRUG: Placebo to TS-142
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transcrestal Sinus Lift Using Osseodensification Versus Lateral Window Technique
Status: COMPLETED
Conditions: Dental Implant|Sinus Lifting
Interventions: PROCEDURE: Crestal Maxillary Sinus Floor Elevation using Osseodensification|PROCEDURE: Lateral Maxillary Sinus Floor Elevation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Psychotherapy Outcome With Feedback
Status: UNKNOWN
Conditions: Individual Psychiatric Disorder|Couple Dysfunction|Family Dysfunction
Interventions: OTHER: Systemic Therapy Inventory of Change (STIC)|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Isoleucine Intake and Intermediary Metabolism in Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Oral Supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Clinical Study of Gulingji Capsule in the Treatment of Idiopathic Oligospermia, Asthenia, and Teratozoospermia
Status: UNKNOWN
Conditions: Oligospermia
Interventions: DRUG: Guilingji Capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optical Coherence Tomography Angiography (OCTA) - Directed PDT Triple Therapy
Status: WITHDRAWN
Conditions: Exudative Age Related Macular Degeneration
Interventions: DRUG: Ranibizumab|DEVICE: Photodynamic laser treatment (PDT)|DRUG: Triamcinolone Acetonide|DRUG: verteporfin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the HBDL Coil Transcranial Magnetic Stimulation (TMS) Device - Feasibility Study for the Treatment of Borderline Personality Disorder
Status: UNKNOWN
Conditions: Borderline Personality Disorder
Interventions: DEVICE: HBDL-coil Repetitive Deep Transcranial magnetic stimulation (rdTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Isolation Device to Contain Aerosol During Aerosol Generating Procedures in the Operating Room
Status: COMPLETED
Conditions: Aerosol Containment|Aerosol Generating Procedure
Interventions: DEVICE: Novel isolation device to contain aerosol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Iron Metabolism Disorders in Patients With Sepsis or Septic Shock.
Status: UNKNOWN
Conditions: Iron-deficiency|Iron Deficiency Anemia|Anemia of Chronic Disease|Sepsis|Septic Shock
Interventions: DIAGNOSTIC_TEST: ferritin; iron; transferrin; transferrin saturation; hemoglobin in reticulocyte; hepcidin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Albuterol in Individuals With Late-onset Pompe Disease
Status: COMPLETED
Conditions: Pompe Disease
Interventions: DRUG: Albuterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Mesenchymal Stem Cells Transplantation in the Treatment of Bronchopulmonary Dysplasia
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia
Interventions: COMBINATION_PRODUCT: stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Periodontal Treatment on Psoriasis
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: OTHER: Psoriatic measurements|OTHER: Non-surgical periodontal treatment|OTHER: saliva samples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ENAVOgliflozin Outcome Trial in Patients With Severe Aortic Stenosis After Transcatheter Aortic Valve Replacement
Status: NOT_YET_RECRUITING
Conditions: Aortic Valve Stenosis
Interventions: DRUG: Enavogliflozin|DRUG: Standard-of-Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study on the Efficacy of Exclusive Odontological and Medical Treatment in Chronic Dental Maxillary Sinusitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Maxillary Sinusitis
Interventions: PROCEDURE: Dental and medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Local Infiltration Anesthesia With Ropivacaine on Pain After Primary Total Hip Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis, Hip
Interventions: PROCEDURE: local infiltration anesthesia using Ropivacaine and Epinephrine|PROCEDURE: local infiltration anesthesia using saline|PROCEDURE: Multimodal analgesic regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Low and High Dose Dextrose Prolotherapy in the Treatment of Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: DRUG: Dextrose 5% in water|DRUG: Dextrose 15 % in Water|DRUG: Isotonic sodium chloride solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: hMG or Recombinant FSH on OHSS Prevention in PCOS Patients Undergoing IVF
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: HMG|DRUG: rFSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Prevalence of Malaysian Children Aged ≥ 6 to ≤ 36 Months at Risk of Anaemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Anemia
Interventions: DIAGNOSTIC_TEST: measuring Total Haemoglobin (SpHb) using Masimo Rad-67.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Occurrence of Early Thrombosis on Central Venous Catheter by Ultrasound in Pediatric Intensive Care Unit
Status: COMPLETED
Conditions: Central Venous Catheters
Interventions: OTHER: Ultrasound scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single-Dose Pharmacokinetics and Safety of Oral Lofexidine in Hepatically-Impaired Subjects
Status: COMPLETED
Conditions: Liver Failure
Interventions: DRUG: Lofexidine Hydrochloride (HCl) tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interleukin-7 (CYT107) Treatment of Idiopathic CD4 Lymphocytopenia: Expansion of CD4 T Cells (ICICLE)
Status: TERMINATED
Conditions: Idiopathic CD4+ T-Lymphocytopenia
Interventions: DRUG: CYT107
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Rhythmic Auditory Cueing on Stepping in Place in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Stepping-in-place exercise with external auditory cues|DEVICE: Transcranial magnetic stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Attention Training on Emotion Regulation and Stress Related Complaints During COVID-19
Status: TERMINATED
Conditions: Rumination|Anxiety|Stress|Depressive Symptoms
Interventions: BEHAVIORAL: Behavioral: OCAT-sham|BEHAVIORAL: Behavioral: OCAT|OTHER: psycho-education video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Partıcıpatıon in Care of Mothers
Status: ENROLLING_BY_INVITATION
Conditions: Newborn|Attachment|Self Confidence|Nursing Caries
Interventions: OTHER: Nursing care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Curcumin's Effect on Diabetic Patients With Atherosclerotic Cardiovascular Risk
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Dyslipidemias|Hypertension
Interventions: DIETARY_SUPPLEMENT: Puritans Pride Turmeric curcumin® 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Endarterectomy Versus Suprageniculate Femoropopliteal Bypass
Status: UNKNOWN
Conditions: Peripheral Arterial Occlusive Disease|Atherosclerosis
Interventions: PROCEDURE: Remote endarterectomy of the superficial femoral artery|PROCEDURE: Suprageniculate femoropopliteal bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venous Ulcer: Endovenous Radiofrequency Treatment Trial
Status: UNKNOWN
Conditions: Varicose Ulcer|Varicose Veins of Lower Limb|Saphenous Vein Injury
Interventions: PROCEDURE: Radiofrequency ablation|PROCEDURE: Multilayer Compressive Bandage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Glyburide/Metformin HCl 5 mg/500 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Glyburide and Metformin Hydrochloride Tablets 5 mg/500 mg|DRUG: CLUCOVANCE® 5 mg/500 mg Tablets, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Hydroxyzine for the Prevention of Pruritus From Spinal Morphine in Transabdominal Hysterectomy Patients
Status: COMPLETED
Conditions: Pruritus|Nausea|Vomiting
Interventions: DRUG: hydroxyzine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION