pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Long Acting GnRH Antagonist in PCOS Women Undergoing IVF
Status: UNKNOWN
Conditions: Polycystic Ovarian Syndrome|Ovarian Hyperstimulation Syndrome|Invitro Fertilization
Interventions: DRUG: GnRH antagonist depot Degarelix
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vaccine Therapy and Sargramostim in Treating Patients With Sarcoma or Brain Tumor
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Gastrointestinal Stromal Tumor|Sarcoma
Interventions: BIOLOGICAL: sargramostim|BIOLOGICAL: telomerase: 540-548 peptide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Morphine and Fentanyl/Midazolam in Intensive Care Unit
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: DRUG: Morphine infusion|DRUG: Fentanyl and Midazolam infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Continuous Erector Spinae Block Versus Continuous Paravertebral Block
Status: RECRUITING
Conditions: Pain, Postoperative
Interventions: PROCEDURE: continuous erector spinae block (ESB)|PROCEDURE: continuous paravertebral block (PVB)|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of MET on PPDH, Neck Pain and Disability After Cesarean Section
Status: RECRUITING
Conditions: Post-Dural Puncture Headache|Cesarean Section Complications
Interventions: OTHER: Traditional Physical Therapy|OTHER: Muscle Energy Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Clinical Trials to Enhance Elders' Oral Health" ("TEETH")
Status: COMPLETED
Conditions: Tooth Loss|Periodontal Disease|Tooth Decay
Interventions: DRUG: Chlorhexidine rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: S-Condom Uterine Tamponade in Controlling Atraumatic Postpartum Haemorrhage (PPH) - RCT
Status: COMPLETED
Conditions: Post Partum Hemorrhage
Interventions: DEVICE: S-Condom Uterine Tamponade|DEVICE: Traditional condom catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Non-inferiority of Clinical Trials in Comparison With the Length of Totally Implemented Porth-a-Cath Maintenance From 60 Versus 90 Days
Status: UNKNOWN
Conditions: Catheter Obstruction
Interventions: OTHER: 90 days interval between catheter maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Muscular Resistance Test in the Elastic Tube: Reliability and Training of the Proposed Method
Status: COMPLETED
Conditions: Muscle Strength Quantitative Trait Locus 1
Interventions: OTHER: isokinetic dynamometer|OTHER: elastic tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Virtual Reality Avatar Therapy for People Hearing Voices
Status: RECRUITING
Conditions: Psychosis|Schizophrenia|Schizo Affective Disorder|Hearing Voices When No One is Talking (Symptom)
Interventions: BEHAVIORAL: Virtual Reality Avatar Therapy (VRAT)|BEHAVIORAL: Assertiveness Training Program (ATP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Switching From a Regimen Consisting of the Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate Single-Tablet Regimen (STR) to the Emtricitabine/Rilpivirine/Tenofovir Disoproxil Fumarate STR
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: FTC/RPV/TDF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of the Complex of Carnitine Orotate and Biphenyl Dimethyl Dicarboxylate in the Adjuvant Therapy of Chronic Hepatitis D in Real Clinical Practice: a Prospective Cohort Study
Status: WITHDRAWN
Conditions: Chronic Viral Hepatitis B With Delta-Agent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inherited Retinal Degenerative Disease Registry
Status: RECRUITING
Conditions: Eye Diseases Hereditary|Retinal Disease|Achromatopsia|Bardet-Biedl Syndrome|Bassen-Kornzweig Syndrome|Batten Disease|Best Disease|Choroidal Dystrophy|Choroideremia|Cone Dystrophy|Cone-Rod Dystrophy|Congenital Stationary Night Blindness|Enhanced S-Cone Syndrome|Fundus Albipunctatus|Goldmann-Favre Syndrome|Gyrate Atrophy|Juvenile Macular Degeneration|Kearns-Sayre Syndrome|Leber Congenital Amaurosis|Refsum Syndrome|Retinitis Pigmentosa|Retinitis Punctata Albescens|Retinoschisis|Rod-Cone Dystrophy|Rod Dystrophy|Rod Monochromacy|Stargardt Disease|Usher Syndrome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: School-Based Assessment of Micronutrient Interventions in Adolescents in Burkina Faso
Status: COMPLETED
Conditions: Anemia
Interventions: DIETARY_SUPPLEMENT: Iron and folic acid (IFA)|DIETARY_SUPPLEMENT: Multiple Micronutrient Supplements (MMS) and loading dose of Iron and Folic Acid (IFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Portion-controlled Diet Will Prevent Weight Gain in Diabetics Treated With ACTOS
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: OTHER: Actos plus standard diet|OTHER: Actos plus structured diet|OTHER: Metformin plus standard diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internal Jugular Vein Compression Collar for Novel Symptomatic Treatment of Venous Pulsatile Tinnitus
Status: COMPLETED
Conditions: Pulsatile Tinnitus
Interventions: DEVICE: Internal Jugular Vein Compression Collar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Evaluating Safety of Sitagliptin Combined With Peg-IFN Alfa-2a + Ribavirin in Chronic Hepatitis C Patients
Status: TERMINATED
Conditions: Hepatitis C
Interventions: DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study for Post-Marketing Surveillance of Nesina® Tablet Monotherapy or Combination Therapy in Participants With Type 2 Diabetes (T2DM) in South Korea
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Alogliptin Benzoate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of EZN-2208 Administered With or Without Cetuximab in Patients With Metastatic Colorectal Carcinoma
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: EZN-2208, Cetuximab and Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Hydroxychloroquine to Improve Endothelial Dysfunction in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Double-Blind Phase 2 Efficacy and Safety of Autologous HB-MSCs vs Placebo for Treatment of Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: HB-adMSCs|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective, Post-registration, Interventional, Randomized, in Parallel Groups, Multicenter Eurasian Clinical Study of DERIVO®/DERIVO® Mini Aneurysm Embolization Device, Europe-Asia
Status: RECRUITING
Conditions: Intracranial Aneurysm
Interventions: DRUG: ticagrelor (tablets, 180 mg) or prasugrel (tablets, 10 mg).|DRUG: combination of clopidogrel (tablets, 75 mg) and acetylsalicylic acid (ASA, tablets, 100 mg) or a combination of ticagrelor (tablets, 180 mg) and ASA (tablets, 100 mg).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Behaviour Change Interventions on Use of Public Handwashing Stations in Bangladesh
Status: COMPLETED
Conditions: Hand Washing|Handwashing|Covid19
Interventions: BEHAVIORAL: Low Intensity Nudges|BEHAVIORAL: High Intensity Activities|BEHAVIORAL: BRAC's business-as-usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 3D HD Versus 2D HD in Laparoscopic Inguinal Hernia Repair: a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Hernia, Inguinal|Hernia
Interventions: DEVICE: 3D HD laparoscopy|DEVICE: 2D HD laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Volumetric Integral Phase-shift Spectroscopy for Noninvasive Detection of Hemispheric Bioimpedance Asymmetry in Acute Brain Pathology
Status: COMPLETED
Conditions: Stroke|Stroke, Acute|Ischemic Stroke|Hemorrhage|Clot (Blood); Brain|Subarachnoid Hemorrhage|Cerebral Infarction|Cerebral Hemorrhage|Cerebral Stroke|Intracerebral Hemorrhage|Intracerebral Injury
Interventions: DIAGNOSTIC_TEST: VIPS Monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Post-marketing Study in Femoral Popliteal Artery of Drug Coated Balloon Used for Treatment of Lower Limb Ischemia
Status: RECRUITING
Conditions: Peripheral Arterial Disease (PAD)
Interventions: DEVICE: Drug eluting Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-escalation Study to Assess Safety, Tolerability and Pharmacokinetics of MEDI-573 in Japanese Subjects
Status: COMPLETED
Conditions: Cancer|Advanced Solid Malignancies
Interventions: DRUG: MEDI-573
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acid-Sensing Ion Channel and Migraine Disease Proof of Concept Study on the Efficacy of Amiloride in the Prophylaxis of Migraine Aura
Status: RECRUITING
Conditions: Migraine With Aura
Interventions: DRUG: Amiloride|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Denosumab (DMAB) Discontinuation And Switching In Glucocorticoid-Induced Osteoporosis (GIOP): A Pilot Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoporosis
Interventions: DRUG: DMAB Discontinuation and Switching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Balloon Catheter Compared With Double Balloon Catheter for Ripening of the Unfavorable Cervix
Status: COMPLETED
Conditions: Induction of Labor
Interventions: DEVICE: Foley catheter|DEVICE: Atad catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability and Beneficial Properties of Coffee and Cocoa Bioactive Compounds
Status: COMPLETED
Conditions: Diet Modification|Cardiovascular Risk Factor|Nutritional and Metabolic Diseases
Interventions: OTHER: cup of espresso coffee|OTHER: cocoa-based products containing coffee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fludarabine, Total-Body Irradiation, and Donor Stem Cell Transplant Followed By Cyclosporine and Mycophenolate Mofetil in Treating Patients With Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: mycophenolate mofetil|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Pilot-Study of Thalidomide in Amyotrophic Lateral Sclerosis (ALS)
Status: TERMINATED
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: DRUG: Thalidomide (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding How the Immune System Responds to Viruses in Peanut Allergic Children Undergoing Peanut Oral Immunotherapy
Status: COMPLETED
Conditions: Peanut Allergy
Interventions: OTHER: Peanut flour
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual Perfusion Imaging for Characterizing Vascular Architecture of Brain Lesions
Status: RECRUITING
Conditions: Brain Tumor|Brain Metastases
Interventions: DIAGNOSTIC_TEST: Dynamic susceptibility contrast magnetic resonance imaging (DSC MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase Ib Study of SC Milatuzumab in SLE
Status: COMPLETED
Conditions: Lupus Erythematosus, Cutaneous|Lupus Erythematosus, Discoid|Lupus Erythematosus, Systemic|Lupus Vasculitis, Central Nervous System|Lupus Nephritis
Interventions: DRUG: milatuzumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Methylphenidate for Smoking Abstinence
Status: COMPLETED
Conditions: Smoking
Interventions: DRUG: Methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of Continuous Intravenous L-citrulline During Sickle Cell Pain Crisis or Acute Chest Syndrome
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: Intravenous citrulline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesia Duration of Dexamethasone, Buprenorphine, or Clonidine With Ropivacaine for Interscalene Nerve Block
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: DRUG: Ropivacaine 0.75%|DRUG: Ropivacaine 0.75% + 300 mcg Buprenorphine|DRUG: Ropivacaine 0.75% + 75 mcg clonidine|DRUG: Ropivacaine 0.75% + 8 mg dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Pain Self-Management in Total Knee Arthroplasty
Status: RECRUITING
Conditions: Osteo Arthritis Knee|Knee Pain Chronic|Surgery
Interventions: BEHAVIORAL: Savoring Meditation|BEHAVIORAL: Pain Self-Management and Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety of Empliciti® (Elotuzumab) When Treating Patients With Multiple Myeloma in Taiwan
Status: RECRUITING
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: DRUG: Elotuzumab in combination with pomalidomide and dexamethasone|DRUG: Elotuzumab in combination with lenalidomide and dexamethasone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study for Patients With Neurogenic Orthostatic Hypotension (NOH) Using Droxidopa
Status: COMPLETED
Conditions: Symptomatic Neurogenic Orthostatic Hypotension (NOH)|Non-diabetic Neuropathy|Primary Autonomic Failure|Dopamine Beta Hydroxylase Deficiency
Interventions: DRUG: Placebo|DRUG: Droxidopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lumenate Observational Vasospasm Interventional Trial (LOVIT)
Status: UNKNOWN
Conditions: Vasospasm, Intracranial|Subarachnoid Hemorrhage
Interventions: DEVICE: Lumenate Intraluminal Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding Pneumococcal Carriage and Disease 2017-2020
Status: UNKNOWN
Conditions: Streptococcus Pneumoniae Infection|Streptococcus Pneumoniae, Invasive Disease|Streptococcal Pneumonia
Interventions: DIAGNOSTIC_TEST: Nasopharyngeal swab|DIAGNOSTIC_TEST: blood sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Personalized Vaccine Immunotherapy in Combination With Checkpoint Inhibitor for Treatment of Triple Negative Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8|Early Stage Triple-Negative Breast Carcinoma|Locally Advanced Triple-Negative Breast Carcinoma|Metastatic Triple-Negative Breast Carcinoma|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage IV Breast Cancer AJCC v8|Recurrent Breast Carcinoma|Unresectable Triple-Negative Breast Carcinoma
Interventions: BIOLOGICAL: Ipilimumab|BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Vaccine Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Artificial Intelligence for Learning Point-of-Care Ultrasound
Status: ENROLLING_BY_INVITATION
Conditions: Education, Medical|Ultrasound Imaging
Interventions: OTHER: Ultrasound with Artificial Inteligence Engabled|OTHER: Ultrasound without Artificial Intelligence Enabled
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Efficacy of Metformin Produced by Pars Mino Co in Comparison With Canadian Apotex Co.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2 AND Metformin
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Neonatal Erythropoietin And Therapeutic Hypothermia Outcomes in Newborn Brain Injury (NEATO)
Status: COMPLETED
Conditions: Hypoxic-ischemic Encephalopathy|Neonatal Encephalopathy|Birth Asphyxia
Interventions: DRUG: Erythropoietin|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient-controlled Versus Anesthesiologist-controlled Propofol-remifentanil in Awake Craniotomy
Status: WITHDRAWN
Conditions: Awake Craniotomy for Brain Tumour Surgery
Interventions: PROCEDURE: Patient-Controlled Sedation/Analgesia|PROCEDURE: Anesthetist-Controlled Sedation/Analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Associative Peripheral Stimulation for Reduction of Motor Impairment During Acute Period of Stroke Recovery
Status: RECRUITING
Conditions: Stroke|Stroke, Acute|Stroke, Ischemic|Stroke, Hemorrhagic|Hemiparesis|Hemiparesis;Poststroke/CVA|Weakness of Extremities as Sequela of Stroke|Stroke Sequelae|Upper Extremity Paresis
Interventions: DEVICE: Associative Peripheral Stimulation (APS) 1.0|DEVICE: Peripheral Neuromuscular Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Curcumin Supplementation on Gut Barrier Function in Patients With Metabolic Syndrome
Status: COMPLETED
Conditions: Obesity|High Blood Pressure|High Cholesterol|Type2 Diabetes|Heart Diseases
Interventions: DIETARY_SUPPLEMENT: Curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Early Screening of Pancreatic Lesions : Development of New Imaging Tools
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: RADIATION: MRI with additional sequences|RADIATION: MRI|PROCEDURE: Left pancreatectomy or pancreaticoduodenectomy|RADIATION: MRI with additional sequences
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Time and Dose Evaluation of Stearidonic Acid (SDA) to Eicosapentaenoic Acid (EPA) in Red Blood Cells
Status: COMPLETED
Conditions: Sudden Cardiac Death|Sudden Cardiac Arrest|Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Safflower Oil|DIETARY_SUPPLEMENT: EPA|DIETARY_SUPPLEMENT: SDA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Follow-up Study to Describe the Safety of Study Participants Who Received RSVPreF3 Maternal Vaccination (Any Dose) or Controls From Previous RSV MAT Studies During Any Pregnancy Conceived Post Vaccination/Control
Status: RECRUITING
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSVPreF3 vaccine|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Stereotactic Body Radiation Therapy and Radium (Ra-223) Dichloride in Prostate Cancer That Has Spread to the Bones
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Radium dichloride|DIAGNOSTIC_TEST: PET Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metal or Plastic Stents to Relieve Obstruction of Obstructive Jaundice Prior to Resection of Periampullary Tumors.
Status: COMPLETED
Conditions: Obstructive Jaundice|Periampullary Tumour
Interventions: PROCEDURE: Plastic stent (7-10Fr)|PROCEDURE: Self Expanding Metal Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study for Safety and Efficacy Evaluation of Various Doses of STP705 in Reducing Keloid Recurrence
Status: COMPLETED
Conditions: Keloid
Interventions: DRUG: STP705|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Response to Therapeutic Intervention in Clinical High Risk (CHR) for Psychosis
Status: NOT_YET_RECRUITING
Conditions: Psychosis; Schizophrenia-Like|Healthy Controls
Interventions: DEVICE: Mb-rt-fMRI-NFB|DEVICE: Sham mb-rt-fMRI-NFB|DEVICE: rTMS|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Placebo-controlled Trial of Hydroxychloroquine in Outpatient Cases With Coronavirus Disease 2019 (COVID-19)
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prostatic Acid Phosphatase (PAP) Vaccine in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: pTVG-HP with rhGM-CSF|BIOLOGICAL: pTVG-HP with rhGM-CSF|BIOLOGICAL: pTVG-HP with rhGM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EBD RCT Trial in Living Donor Liver Transplantation
Status: RECRUITING
Conditions: Liver Transplantation|Liver Transplant; Complications|Bile Stricture|Bile Leakage From Biliary Anastomosis
Interventions: PROCEDURE: External biliary drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of a Subunit Trivalent Influenza Vaccine, Northern Hemisphere Formulation 2013/2014, Including MF59C.1 Adjuvant, in Healthy Adults ≥65 Years of Age
Status: COMPLETED
Conditions: Human Influenza
Interventions: BIOLOGICAL: aTIV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Role of Positron Emission Mammography (PEM) Flex Solo II Positron Emission Tomography (PET) Scanner in Evaluating Neoadjuvant Chemotherapy Response in Patients With Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DEVICE: PEM Flex Solo II PET Scanner|DEVICE: MRI scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of House Dust Mite Allergoid in the Treatment of Bronchial Asthma
Status: COMPLETED
Conditions: Respiratory Hypersensitivity
Interventions: BIOLOGICAL: Acaroid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Tight Control of Blood Glucose During Hyper-CVAD Chemotherapy For Acute Lymphocytic Leukemia (ALL)
Status: TERMINATED
Conditions: Leukemia|Lymphoma
Interventions: DRUG: Insulin Glargine|DRUG: Insulin Aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Parameters as a Predictor of Fever After Percutaneous Nephrolithotomy
Status: COMPLETED
Conditions: Urinary Tract Infection Bacterial|Nephrolithiasis
Interventions: DIAGNOSTIC_TEST: peripheric blood count
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Three Induction Treatments on Cryptococcal Meningitis
Status: UNKNOWN
Conditions: Cryptococcal Meningitis|HIV/AIDS
Interventions: DRUG: Voriconazole 200mg|DRUG: amphotericin B deoxycholate (0.4-0.5mg/kg/d)|DRUG: Amphotericin B-deoxycholate (0.7-1.0mg/kg/d)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Lactobacillus in Adjuvant Treatment of RVVC
Status: RECRUITING
Conditions: Recurrent Vulvovaginal Candidiasis
Interventions: DRUG: clotrimazole vaginal tablets|DRUG: Clotrimazole vaginal tablets+ Lactobacillus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of COPD Patients With BoraCare® Remote Monitoring Solution Including BVS3 Early Detection Score for COPD Exacerbations
Status: NOT_YET_RECRUITING
Conditions: COPD
Interventions: DEVICE: Boracare remote monitoring solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Binimetinib 3 x 15 mg and 45 mg Formulations
Status: COMPLETED
Conditions: Melanoma|BRAF V600 Mutation|Unresectable Melanoma|Metastatic Melanoma
Interventions: DRUG: Binimetinib Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ketamine in Patients Undergoing Anterior Cervical Discectomy and Fusion
Status: WITHDRAWN
Conditions: Anesthesia|Pain|Surgery
Interventions: DRUG: Saline|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety Study of VESIcare® (Solifenacin Succinate) in Patients Wishing to Switch From Detrol LA® for Treatment of Overactive Bladder
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: solifenacin succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigational Study of Experimental Medication BMS-986278 Given With the Antibiotic Rifampin in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986278|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expanding the Scope of Post-transplant HLA-specific Antibody Detection and Monitoring in Renal Transplant Recipients
Status: RECRUITING
Conditions: Kidney Transplant|Renal Transplant Failure|Kidney Transplant Rejection|Frailty|Kidney Transplant; Complications|Transplant Dysfunction|Diagnosis|Renal Transplant
Interventions: DIAGNOSTIC_TEST: cf-DNA|DIAGNOSTIC_TEST: Immunological Events following renal transplant in older age|OTHER: Determining Predictive Models for Post-transplant HLA-specific Antibody Formation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: New Validated Recipes for Double-blind Placebo-controlled Low Dose Food Challenges
Status: COMPLETED
Conditions: Allergy
Interventions: OTHER: Elemental E028 with added food allergens|OTHER: Elemental E028
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Newborn's First Bath Time on Physiological Variables
Status: COMPLETED
Conditions: Baths
Interventions: OTHER: Preterm group bathing 24 hours after birth.|OTHER: Preterm group bathing 48 hours after birth.|OTHER: Early term group bathing 24 hours after birth.|OTHER: Early term group bathing 48 hours after birth.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Electrical Inhibition of Human Preterm Contractions
Status: RECRUITING
Conditions: Preterm Labor|PreTerm Birth|Preterm Labor With Delivery Nos
Interventions: DEVICE: Electrical Uterine Pacemaker
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pictorial Warning Labels & Memory for Relative & Absolute Cigarette Health-risk Information Over Time in Adult Smokers
Status: COMPLETED
Conditions: Smoking Cessation|Smoking, Cigarette
Interventions: BEHAVIORAL: text-only PWL|BEHAVIORAL: low arousal graphic PWL|BEHAVIORAL: high arousal graphic PWL|BEHAVIORAL: absolute risk|BEHAVIORAL: relative risk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren's Contracture
Status: RECRUITING
Conditions: Dupuytren Contracture|Dupuytren's Disease|Contracture|Joint Diseases|Musculoskeletal Diseases|Fibroma|Neoplasm, Fibrous Tissue|Neoplasms, Connective Tissue|Neoplasms, Connective and Soft Tissue|Neoplasms by Histologic Type|Neoplasms|Connective Tissue Diseases
Interventions: PROCEDURE: Percutaneous needle fasciotomy|DRUG: Corticosteroid injection|OTHER: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Gabapentin Enacarbil on Opioid Consumption and Pain Scores
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Gabapentin enacarbil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Empower@Home:Connected - Feasibility and Preliminary Effect Study
Status: COMPLETED
Conditions: Depression|Loneliness|Social Isolation|Depressive Disorder|Mood Disorders|Mental Disorder
Interventions: BEHAVIORAL: Empower@Home:Connected
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dasatinib and Venetoclax in Treating Patients With Philadelphia Chromosome Positive or BCR-ABL1 Positive Early Chronic Phase Chronic Myelogenous Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Philadelphia Chromosome Positive, BCR-ABL1 Positive Chronic Myelogenous Leukemia
Interventions: DRUG: Dasatinib|OTHER: Laboratory Biomarker Analysis|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)
Status: RECRUITING
Conditions: Adult Glioblastoma|High Grade Glioma|WHO Grade III or IV Malignant Glioma
Interventions: BIOLOGICAL: Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP liposome vaccine administered intravenously (RNA loaded lipid particles, RNA-LPs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III, Active-Controlled Study of SHR-A1811 Versus Trastuzumab Emtansine (T-DM1) in HER2-Positive Primary Breast Cancer Participants With Residual Invasive Disease Following Neoadjuvant Therapy
Status: NOT_YET_RECRUITING
Conditions: HER2-Positive Primary Breast Cancer Participants With Residual Invasive Disease Following Neoadjuvant Therapy
Interventions: DRUG: SHR-A1811|DRUG: Trastuzumab Emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Study the Influence of GCSF on Natural History of Acute On Chronic Liver Failure After the Acute Phase
Status: TERMINATED
Conditions: Acute on Chronic Liver Failure
Interventions: DRUG: Peg GCSF|BIOLOGICAL: 20% Albumin|DIETARY_SUPPLEMENT: Nutrition|OTHER: Bowel wash|DRUG: Terlipressin 1- 4mg,if indicated|DRUG: Meropenem or Imepenem, if indicated|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability and Pharmacokinetic Dose Escalation Study of HC-ER in Patients With Osteoarthritis Pain
Status: COMPLETED
Conditions: Osteoarthrosis
Interventions: DRUG: 10 mg of Hydrocodone Bitartrate Extended Release (HC-ER)|DRUG: 20 mg of Hydrocodone Bitartrate Extended Release (HC-ER)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: SAKK - a Trial to Evaluate Antitumor Efficacy of Faslodex® After Aromatase Inhibitor Failure in Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture Point P6 Stimulation for Reduction of Nausea and Vomiting During Cesarean
Status: COMPLETED
Conditions: Nausea|Vomiting|Satisfaction
Interventions: DEVICE: Acupressure Point P6 stimulator|DRUG: Metoclopramide|DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: DCE-MRI Using Dotarem® in Evaluation of Therapeutic Response to Sorafenib in Patients With Advanced Stage HCC
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Gadoterate meglumine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety of Toremifene and Tamoxifen Therapy in Premenopausal Patients With Operable Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Toremifene|DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibody Persistence at Age 3.5 and 4.5 Years After Primary and Booster DTaP-IPV-Hep B-PRP~T or Infanrix Hexa Vaccination
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Whooping Cough|Hepatitis B|Poliomyelitis|Haemophilus Influenzae Type b
Interventions: BIOLOGICAL: DTaP-IPV-Hep B- PRP~T + Prevenar + Rotarix vaccine|BIOLOGICAL: DTaP- IPV-Hep B-PRP~T + Prevenar + Rotarix + Infanrix hexa vaccine|BIOLOGICAL: Infanrix hexa + Prevenar + Rotarix vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SURFAXIN® Treatment for Prevention of Bronchopulmonary Dysplasia (BPD) in Very Low Birth Weight (VLBW) Infants.
Status: TERMINATED
Conditions: Respiratory Distress Syndrome, Newborn|Premature Birth|Bronchopulmonary Dysplasia
Interventions: DRUG: Lucinactant 175 mg/kg|DRUG: Lucinactant 90 mg/kg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Generation of Cancer Antigen-Specific T-cells From Human Induced Pluripotent Stem Cells (iPSC) for Research and Potential FutureTherapy
Status: TERMINATED
Conditions: Gastrointestinal Cancers|Breast Cancer|Pancreatic Cancer|Melanoma|Lung Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transcutaneous Electrical Nerve Stimulation During Outpatient Endometrial Biopsy
Status: COMPLETED
Conditions: Endometrial Diseases|Pain, Postoperative
Interventions: DEVICE: TENS 7000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Full Versus Partial Repairing of Soft Tissue Surrounding the Hip in Arthroplasty for Femoral Neck Fractures
Status: UNKNOWN
Conditions: Femoral Neck Fracture
Interventions: PROCEDURE: Full Repairng of soft tissue surrounding the hip|PROCEDURE: Partial Repairng of soft tissue surrounding the hip
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Versus Late CRRT in ACLF Patients With Septic Shock and AKI
Status: UNKNOWN
Conditions: Septic Shock and Acute Kidney Injury
Interventions: OTHER: Early CRRT|OTHER: Late CRRT|OTHER: Standard Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Intra-articular Parameters by Doppler Ultrasound in Patients With Hemophilic Ankle Arthropathy
Status: COMPLETED
Conditions: Hemophilia
Interventions: OTHER: Manual therapy|OTHER: Placebo manual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Repetitive Transcranial Magnetic Stimulation on Cerebral Autoregulation in Patients With Acute Ischemic Stroke
Status: RECRUITING
Conditions: Transcranial Magnetic Stimulation
Interventions: PROCEDURE: Repetitive transcranial magnetic stimulation|PROCEDURE: Sham repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Isotretinoin for Photoaging: Results of a Randomized Controlled Phase II Trial
Status: COMPLETED
Conditions: Photoaging|Epidermal p53 Expression
Interventions: DRUG: oral isotretinoin and Mexoryl SX / XL|DRUG: Mexoryl XL / SX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Albumin and Midodrine Versus Albumin Alone in Outcome of Refractory Ascites in Patients With Decompensated Cirrhosis.
Status: UNKNOWN
Conditions: Liver Cirrhosis
Interventions: DRUG: Midodrine|BIOLOGICAL: Albumin|OTHER: Standard Medical Treatment|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Hepatocyte Growth Factor (HGF) Via Plasmid Vector to Improve Perfusion in Critical Limb Ischemia Patients With Peripheral Ischemic Ulcers
Status: COMPLETED
Conditions: Arterial Occlusive Disease|Peripheral Vascular Disease|Ischemia|Ulcers
Interventions: GENETIC: HGF plasmid|GENETIC: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Lenalidomide for Adult Histiocyte Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Langerhans Cell Histiocytosis (LCH)|Histiocytoses Erdheim-chester Disease|Histiocytic Sarcoma (HS)
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computer-based Training of Face Recollection to Improve Face Recognition in Developmental Prosopagnosia
Status: RECRUITING
Conditions: Developmental Prosopagnosia
Interventions: BEHAVIORAL: cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-speed Power Training in Older Adults With Knee Osteoarthritis (OA)
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: High-speed power training|OTHER: Slow-speed strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of Carvedilol in Chronic Chagas Cardiomyopathy
Status: COMPLETED
Conditions: Chagas Cardiomyopathy|Heart Failure|Dilated Cardiomyopathy
Interventions: DRUG: RASi plus carvedilol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PMCF Study of the CLS Brevius Stem With Kinectiv Technology
Status: TERMINATED
Conditions: Osteoarthritis|Avascular Necrosis|Rheumatoid Arthritis|Femoral Neck Fractures|Prosthesis Failure
Interventions: DEVICE: CLS Brevius stem with Kinectiv technology
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Indication Based Blood Product Transfusion in Patients Undergoing Major Oncological Surgery
Status: NOT_YET_RECRUITING
Conditions: Blood Transfusion
Interventions: PROCEDURE: blood volume loss based blood transfusion|PROCEDURE: hemoglobin concentration based blood transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Paramedic Treatment of Regular Supraventricular Tachycardia
Status: UNKNOWN
Conditions: Supraventricular Tachycardia
Interventions: OTHER: Paramedic|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Fiber and Gut Microbiome Study
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Dietary fiber 1|DIETARY_SUPPLEMENT: Dietary fiber 2|DIETARY_SUPPLEMENT: Dietary fiber 3|DIETARY_SUPPLEMENT: Dietary fiber 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Response-Adapted Therapy With Copanlisib and Rituximab in Untreated Follicular Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Follicular Lymphoma|Non-Hodgkin's Lymphoma|NHL
Interventions: BIOLOGICAL: Rituximab|DRUG: Copanlisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous T-Cell Transplantation and the Immunotherapy of Residual Disease in Breast Cancer: Pilot Study of Vaccine-Driven T-Cell Expansion in Patients Treated With Dose-Intensive Chemotherapy
Status: COMPLETED
Conditions: Breast Neoplasm|Neoplasm Metastasis
Interventions: PROCEDURE: Autologous T cells|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Opaganib, a Sphingosine Kinase-2 (SK2) Inhibitor in COVID-19 Pneumonia
Status: COMPLETED
Conditions: COVID-19|Lung Infection
Interventions: DRUG: Opaganib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT