pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Chemotherapy Before and After Surgery in Treating Children With Wilm's Tumor
Status: UNKNOWN
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: dactinomycin|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: vincristine sulfate|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Subcutaneous Fat Tissue Thickness on Lumbar Transforaminal Epidural Steroid Injection Treatment Success
Status: COMPLETED
Conditions: Lumbar Disc Herniation|Radiculopathy Lumbar|Obesity
Interventions: PROCEDURE: Transforaminal Epidural Steroid Injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Healthy Eating and Active Living Taught at Home (HEALTH) Dissemination & Implementation (D&I)
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: BEHAVIORAL: Healthy Eating & Active Living Taught at Home|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Safety and Efficacy of Dexpramipexole (KNS-760704) in Subjects With Hypereosinophilic Syndrome
Status: UNKNOWN
Conditions: Hypereosinophilic Syndrome
Interventions: DRUG: Dexpramipexole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Insulin Lispro Versus Insulin Aspart in Participants With Type 2 Diabetes on Insulin Pump Therapy
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin Lispro|DRUG: Insulin Aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label, Phase I ZD6474 Head and Neck Cancer Study
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: ZD6474 (vandetanib)|DRUG: Cisplatin|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effects of a Bifidobacterium Breve Strain on Fat Loss in Healthy Adults
Status: COMPLETED
Conditions: Obesity|Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: B. breve|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retrospective Registry of Patients With Acute Heparin-induced Thrombocytopenia Type II
Status: COMPLETED
Conditions: Acute HIT II (Heparin-induced Thrombocytopenia Type II)
Interventions: DRUG: lepirudin|DRUG: danaparoid|DRUG: argatroban|DRUG: fondaparinux
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CompRest - a Comparison Between Sleep Compression and Sleep Restriction for Treating Insomnia
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: Sleep Restriction|BEHAVIORAL: Sleep Compression|BEHAVIORAL: Additional CBT-i components
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Ocular Safety Study of Ivacaftor-Treated Pediatric Patients 11 Years of Age or Younger With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: OTHER: Ophthalmologic examinations|DRUG: Ivacaftor Exposed
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long Term Safety of 125 mg Per Day of Oral Azimilide in Patients With Implantable Cardioverter Defibrillator (ICDs)
Status: COMPLETED
Conditions: Arrhythmias
Interventions: DRUG: azimilide dihydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Balance and Gait in Diabetic Neuropathy
Status: COMPLETED
Conditions: Neuropathy, Diabetic|Pain, Neuropathic|Gait Disorder, Sensorimotor
Interventions: DIAGNOSTIC_TEST: Gait analysis|DIAGNOSTIC_TEST: Balance Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Millet-based Muffins, Glycaemic Response, Insulinemic Response and Gastric Emptying
Status: COMPLETED
Conditions: Healthy|Pre Diabetes
Interventions: OTHER: Wheat muffin|OTHER: Finger millet grain muffin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Probiotics in the Gut Microbiota and H Pylori Density
Status: COMPLETED
Conditions: Helicobacter
Interventions: DIETARY_SUPPLEMENT: Probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Baricitinib (LY3009104) in Participants With Moderate-to-Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Baricitinib|DRUG: Placebo|DRUG: Triamcinolone (Optional)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant MPDL3280A, Nab-paclitaxel and Carboplatin (MAC) in NSCLC
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: MPDL3280A|DRUG: Carboplatin|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Cord Burst Stimulation for Chronic Radicular Pain Following Lumbar Spine Surgery
Status: COMPLETED
Conditions: Back Pain With Radiation|Pain, Postoperative
Interventions: PROCEDURE: Burst Spinal Cord Stimulation|PROCEDURE: Sham spinal cord stimulation|DEVICE: SCS implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Multimodal Analgesia Regimens in Total Knee Arthroplasty
Status: TERMINATED
Conditions: Postoperative Pain
Interventions: DRUG: Continuous perineural infusion of ropivacaine 0.2% 5 ml/h for 48 h|DRUG: Extended Release Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effect of Saxagliptin on Gut Microbiota in Patients With Newly Diagnosed Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes|Obesity
Interventions: DRUG: Saxagliptin (Bristol-Myers Squibb Company)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Glutamine Supplementation in Patients Suffering From Irritable Bowel Syndrome With Impaired Intestinal Permeability
Status: NOT_YET_RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: • Experimental group: treatment with glutamine at a dose of 5g 3 times a day for 8 weeks|DIETARY_SUPPLEMENT: • Control group: treatment with a protein powder (Protifar) (Placébo) 5g 3 times a day for 8 weeks.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ACRYSOF® ReSTOR® Aspheric +3.0 D Add Power Intraocular Lens (IOL)
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: ACRYSOF® ReSTOR® Aspheric +4.0 D Add Power Intraocular Lens|DEVICE: ACRYSOF® ReSTOR® Aspheric +3.0 D Add Power Intraocular Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study of BLU-5937 in Unexplained or Refractory Chronic Cough
Status: TERMINATED
Conditions: Chronic Refractory Cough
Interventions: DRUG: BLU-5937|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Absolute Bioavailability of BIIB122/DNL151 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BIIB122 (DNL151)|DRUG: [14C] BIIB122 ([14C] DNL151)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: China Stroke Primary Prevention Trial 2 for Participants With H-type Hypertension and MTHFR 677 CC/CT Genotype (CSPPT2-CC/CT)
Status: NOT_YET_RECRUITING
Conditions: Hypertension|MTHFR 677 CC or CT Genotype|Elevated Plasma Homocysteine (Hcy≥10µmol/L)|Insufficient Plasma Folate Levels (<12ng/mL)
Interventions: DRUG: Amlodipine besylate|DRUG: Amlodipine besylate and folic acid|DRUG: Amlodipine placebos|DRUG: Amlodipine-folic acid placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contrast Enhanced Ultrasound in COVID-19
Status: COMPLETED
Conditions: Covid19|Multisystem Inflammatory Syndrome in Children (MIS-C)
Interventions: DRUG: Sulfur hexafluoride lipid-type A microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: cisplatin|DRUG: irinotecan hydrochloride|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Soy Bread Diet in Improving Immune Function in Participants With Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Adenocarcinoma
Interventions: COMBINATION_PRODUCT: Dietary Intervention|COMBINATION_PRODUCT: Dietary Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Microbiome and Immunogenity of Saliva During Orthodontic Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Orthodontic Appliances, Removable|Orthodontic Appliances, Fixed|Oral Microbiome|Cell Culture|Periodontal Index
Interventions: PROCEDURE: orthodontic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Replenishing and Maintaining Vitamin D Status in Older Adults in Residential Care Facilities in NI
Status: SUSPENDED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: 3200IU Vitamin D3 per day for 8 weeks|DIETARY_SUPPLEMENT: 20,000IU Vitamin D3 per week for 8 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate Methylprednisolone Pulses and Tacrolimus in Patients With COVID-19 Lung Injury
Status: UNKNOWN
Conditions: COVID-19|Lung Injury
Interventions: DRUG: Tacrolimus|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 2)
Status: RECRUITING
Conditions: Pain Management
Interventions: DEVICE: BreEStim 120|DEVICE: BreEStim 240
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of a Baby Wash/Shampoo and Baby Lotion Versus Baby Wash/Shampoo Alone for Impact on Skin Barrier and Microbiome on Newborns
Status: TERMINATED
Conditions: Healthy
Interventions: OTHER: Baby Wash/Shampoo|OTHER: Baby Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Induced Adult Refractory Active Crohn's Disease Clinical Relieving by Using Thalidomide
Status: UNKNOWN
Conditions: Crohn Disease
Interventions: DRUG: Thalidomide|DRUG: placebo(for thalidomide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hyaluronic Acid, Corticosteroid and Electrotherapy in Subacromial Impingement Syndrome
Status: COMPLETED
Conditions: Subacromial Impingement|Pain, Shoulder
Interventions: DRUG: Hyaluronic acid|DRUG: Corticosteroids Triamcinolone Acetonide|OTHER: Electrotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Group Intervention to Reduce Stress Symptoms
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|HIV Infections
Interventions: BEHAVIORAL: HIV Skills-based Prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Inflammation and Cell Maturation in Preterm Delivery Placentas - in Vitro and in Vivo Effect of Progesterone
Status: COMPLETED
Conditions: Obstetric Labor, Premature
Interventions: BIOLOGICAL: Culture with progesterone|BIOLOGICAL: Culture without progesterone|BIOLOGICAL: Culture with growth factors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Real-World Data Study to Evaluate the Effectiveness of OCA on Hepatic Outcomes in PBC Patients
Status: WITHDRAWN
Conditions: Primary Biliary Cholangitis
Interventions: DRUG: Obeticholic Acid 5 MG|DRUG: Obeticholic Acid 10 MG|DRUG: Standard of Care: UDCA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Subjects With Subjective Cognitive Decline: 18F-Florbetaben Positron Emission Tomography Study
Status: UNKNOWN
Conditions: Subjective Cognitive Decline
Interventions: DRUG: 18F-Florbetaben (FBB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Padeliporfin VTP Treatment for Unresectable Pancreatic Adenocarcinoma
Status: RECRUITING
Conditions: Locally Advanced Unresectable Pancreatic Adenocarcinoma
Interventions: COMBINATION_PRODUCT: Padeliporfin Vascular Targeted Photodynamic (VTP) therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is it Possible to Use the Timed Performance Tests in Lung Transplantation Candidates to Determine the Exercise Capacity?
Status: COMPLETED
Conditions: Pulmonary Rehabilitation|Exercise Capacity|Exercise Test
Interventions: OTHER: Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Nivolumab Given Sequentially With Ipilimumab in Subjects With Advanced or Metastatic Melanoma (CheckMate 064)
Status: COMPLETED
Conditions: Advanced or Metastatic Melanoma
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxycycline and Airway Inflammation in Chronic Obstructive Pulmonary Disease (COPD)
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease|Inflammation|Pulmonary Emphysema
Interventions: DRUG: Doxycycline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Cariprazine Monotherapy for Treatment of Major Depressive Disorder
Status: NOT_YET_RECRUITING
Conditions: Depressive Disorder, Major
Interventions: DRUG: Cariprazine|COMBINATION_PRODUCT: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Stability of the Delta-TT Cup With Polyethylene Insert Versus a Ceramic Insert. A RSA Study.
Status: COMPLETED
Conditions: Osteoarthrosis
Interventions: DEVICE: H-MAX stem & Delta-TT cup + polyethylene|DEVICE: H-MAX stem & Delta-TT cup + ceramic|DEVICE: C2 stem & Delta-TT cup + ceramic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Bevacizumab Combined With Navigated Laser in Patients With Clinically Significant Macula Edema
Status: TERMINATED
Conditions: Clinically Significant Macular Edema
Interventions: DEVICE: laser photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SIDAMI - Sildenafil and Diastolic Dysfunction After Acute Myocardial Infarction (AMI)
Status: COMPLETED
Conditions: Heart Failure, Diastolic
Interventions: DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics as a Prophylaxis to Prevent Clinical Manifestations of Oral Candidosis in Patients With Sjogren's Syndrome
Status: COMPLETED
Conditions: Sjogren's Syndrome
Interventions: DRUG: Probiotic Product - Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Modeling Bronchial Epithelium in Severe Asthma With Human Induced Pluripotent Stem Cells (iPSC)
Status: COMPLETED
Conditions: Severe Asthma|Allergic Bronchopulmonary Aspergillosis (ABPA)
Interventions: OTHER: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pivotal Efficacy and Safety Registration Trial of FP187 in Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Placebo|DRUG: FP187|DRUG: FP187|DRUG: FP187|DRUG: FP187
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Evaluations of Diaphragm and Intercostal Muscle to Predict the Failure of High-Flow Nasal Cannula Therapy
Status: RECRUITING
Conditions: High-flow Nasal Cannula|Ultrasound Evaluation|Diaphragm and Intercostal Muscle
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Iron Supplementation Using Total Dose Infusion and Oral Routes for Treatment of Iron Deficiency Anemia in Pregnancy
Status: COMPLETED
Conditions: Treatment of Iron Deficiency Anemia in Pregnancy
Interventions: DRUG: Theragran Hematinic|DRUG: low molecular weight iron dextran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Food Sequence on the Glycaemic and Insulinaemic Responses
Status: COMPLETED
Conditions: Diabetes Mellitus|Obesity
Interventions: OTHER: Food sequence 1|OTHER: Food sequence 2|OTHER: Food sequence 3|OTHER: Food sequence 4|OTHER: Food sequence 5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sunitinib in Treating Patients With Stage I, Stage II, or Stage III Breast Cancer Who Have Tumor Cells in the Bone Marrow
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: sunitinib malate|OTHER: flow cytometry|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing and Evaluating Interventions to Reduce Inappropriate Prescribing of Antibiotics in Primary Care
Status: COMPLETED
Conditions: Antibiotic Prescribing by GPs for URTI
Interventions: BEHAVIORAL: Persuasive communication|BEHAVIORAL: Action plan|BEHAVIORAL: General intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Methotrexate in Myasthenia Gravis
Status: COMPLETED
Conditions: Myasthenia Gravis
Interventions: DRUG: Methotrexate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 3-month Study of MSDC-0160 Effects on Brain Glucose Utilization, Cognition & Safety in Subjects With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: MSDC-0160|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Physical Activity on Blood Glucose Stability and Energy Stores in Individuals With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Exercise|Hypoglycemia|Carbohydrate Metabolism
Interventions: PROCEDURE: IHE first, CONT second|PROCEDURE: CONT first, IHE second|PROCEDURE: GLU first, GLU-FRU second|PROCEDURE: GLU-FRU first, GLU second
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Short-term Outcomes of Laparoscopic Versus Open Gastrectomy With Lymph Node Dissection for Early Gastric Cancer :a Randomized Controlled Study
Status: NOT_YET_RECRUITING
Conditions: Early Gastric Cancer
Interventions: PROCEDURE: Gastrectomy with lymph node dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Inflammatory Symptoms Reduction With Amoxicillin + Ketoprofen in Acute Pharyngeal Tonsillitis in Pediatric Patients
Status: TERMINATED
Conditions: Pharyngotonsillitis
Interventions: DRUG: Ketoprofen|DRUG: Placebo (for Ketoprofen)|DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postpartum Hypertension Study
Status: NOT_YET_RECRUITING
Conditions: Postpartum Pregnancy-Induced Hypertension|Postpartum Preeclampsia|Pregnancy-Induced Hypertension in Postpartum|Hypertensive Emergency
Interventions: DRUG: Labetalol|DRUG: Nifedipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Schedule Intervention to Increase Sustainable Walking Activity in Midlife Working Adults
Status: UNKNOWN
Conditions: Physical Activity
Interventions: DEVICE: Accelerometer|BEHAVIORAL: Step goal|BEHAVIORAL: Consistent contexts|BEHAVIORAL: Inconsistent contexts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: FANTOM ENCORE Sirolimus-eluting Bioresorbable Scaffold for Treatment of De-novo CAD: the ENCORE-I Study
Status: RECRUITING
Conditions: Percutaneous Coronary Intervention|Myocardial Revascularization|Tomography, Optical Coherence
Interventions: DEVICE: Fantom Encore Bioresorbable scaffold implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Recurrence Rate, Risk Factors for the Recurrence, and Quality of Life in Patients With GERD in Korea-an Observational
Status: COMPLETED
Conditions: The Aim of This Study is to Investigate the Frequency and Related Risk Factors of Recurrence, and Quality of Life in Patients With GERD After Treatment With PPI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Prospective Study Evaluating the Use of Intraoperative Stroke Volume Variation Via the FloTrac Device to Guide Fluid and Vasopressor Management in Head and Neck Free Flaps
Status: COMPLETED
Conditions: Head and Neck Cancer|Patients Requiring a Free Flap Surgery
Interventions: DEVICE: FloTrac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Study to Investigate How Safe and Tolerable the Study Drug MT-2990 is and How MT-2990 is Taken up by the Body in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: MT-2990|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase I/II Study of Dasatinib and Dacarbazine
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: DRUG: Dasatinib and Dacarbazine (DTIC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Prophylactic Intravenous Neostigmine and Atropine in Preventing Post-Dural Puncture Headache Among Parturient Undergoing Spinal Anesthesia for Cesarean Section: A Double-blind Randomized Placebo-controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Acute Pain
Interventions: DRUG: intravenous 50 mL of saline injection of 0.9% after umbilical cord clamping.|DRUG: Neostigmine 20μg/kg (Neostigmine Methylsulphate 0.5 mg, Amriya Pharm.Ind.) and atropine 0.01 mg/kg (diluted in 50 ml saline; 0.9% for 10 min) following umbilical cord clamping.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PASCAL vs. MitralClip for Mitral Valve Transchatheter Edge-to-Edge Repair
Status: COMPLETED
Conditions: Mitral Regurgitation|Functional Mitral Regurgitation|Degenerative Mitral Valve Regurgitation
Interventions: DEVICE: PASCAL vs. MitraClip
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fixed Combination of Dipirone and Codeine Compared to the Isolated Use of Dipyrone and Codeine in Controlling Pain After Pelvic-abdominal Surgery.
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Fixed dose combination Dipyrone and Codeine|DRUG: Dipyrone|DRUG: Codeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of JMT103 in the Treatment of Glucocorticoid Induced Osteoporosis
Status: UNKNOWN
Conditions: Glucocorticoid Induced Osteoporosis
Interventions: DRUG: JMT103|DRUG: Alendronate sodium|DRUG: JMT103 placebo|DRUG: Alendronate sodium placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Explore the Onset of Efficacy on Magnetic Resonance Disease Activity of BG00012 (Dimethyl Fumarate) in Patients With Relapsing remitTing Multiple Sclerosis
Status: WITHDRAWN
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: dimethyl fumarate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adaptive Servo-Ventilation In Acute Heart Failure Patients Protecting the Heart and Kidneys
Status: UNKNOWN
Conditions: Heart Failure|Sleep Apnea, Obstructive
Interventions: DEVICE: Adaptive Servo-Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SBRT for Squamous Cell Carcinoma of the Head and Neck
Status: UNKNOWN
Conditions: Head and Neck Neoplasms|Squamous Cell Carcinoma|Squamous Skin Carcinoma
Interventions: RADIATION: Stereotactic Body Radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction With Proton Pump Inhibitors for Nifedipine ER Tablets
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Nifedipine 60 MG Extended Release Oral Tablet|DRUG: Nifedipine 60 MG Extended Release Oral Tablet|DRUG: omeprazole/sodium bicarbonate|DEVICE: SmartPill (TM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Rituximab in Multirelapsing Minimal Change Disease (MCD) or Focal Segmental Glomerulosclerosis (FSGS)
Status: COMPLETED
Conditions: Nephrotic Syndrome
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exposures to Perinatal Adverse Experiences: Multimodal Omics Signature of Stress Vulnerability and Resilience and Preventive Strategies
Status: RECRUITING
Conditions: Perinatal Depression
Interventions: PROCEDURE: Blood and saliva collection|BEHAVIORAL: Psychometric scales|OTHER: Smartphone app
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: ´Sit Less, Move More' at Work: mHealth Intervention on Office Employees With Diabetes Type 2.
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type II
Interventions: BEHAVIORAL: Walk@WorkApp-Diab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Building Regulation in Dual Generations 2022-2025
Status: RECRUITING
Conditions: Maternal Depression|Self-Regulation, Emotion|Child Mental Disorder|Child Development
Interventions: BEHAVIORAL: Building Regulation in Dual Generations (BRIDGE)|BEHAVIORAL: Dialectical Behavioural Therapy Skill Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microboosting of Atazanavir 300 mg With 50 mg Versus 100mg Ritonavir Daily in HIV-infected Patients: a Pharmacokinetic Study
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: atazanavir 300mg boosted with ritonavir 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Individualized rTMS for Motor Recovery in Stroke Patients
Status: RECRUITING
Conditions: Stroke|Transcranial Magnetic Stimulation
Interventions: DEVICE: Repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunomodulating Effects of Supplementation With 25-OH Vitamin D
Status: COMPLETED
Conditions: Vitamin D Deficiency|Scleroderma, Systemic
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|OTHER: Dietary recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hypertonic Saline Enhances The Field of View of Clinicians and Ease of Procedures
Status: COMPLETED
Conditions: Nasopharyngeal Diseases
Interventions: OTHER: Intranasal solutions application were done including one solution for per patient before nasoendoscopy procedure according to randomization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Impact of Nasal Saline Irrigations on Viral Load in Patients With COVID-19
Status: COMPLETED
Conditions: COVID 19
Interventions: OTHER: Saline Nasal Irrigation|OTHER: Saline with Baby Shampoo Nasal Irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Loteprednol Etabonate Opthalmic Suspension for the Treatment of Dry Eye
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: loteprednol etabonate ophthalmic suspension, 0.5%|DRUG: loteprednol etabonate ophthalmic suspension, 0.5%|DRUG: vehicle of loteprednol etabonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness, Safety and Immunogenicity of GSK Biologicals' HPV Vaccine GSK580299 (Cervarix) Administered in Healthy Adolescents
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: Cervarix|BIOLOGICAL: Engerix-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparative Evaluation of the Efficacy of Intraoral Cryotherapy Versus Intracanal Cryotherapy on Postoperative Pain
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: PROCEDURE: Intraoral Cryotherapy|PROCEDURE: Intracanal Cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Telemonitoring in the Management of Complex IBD in Spain: M-TECCU
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammatory Bowel Disease|Crohn's Disease|Ulcerative Colitis|Telemedicine
Interventions: OTHER: TECCU Software
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Trial Assessing Chemo Mouthpiece Device With Best Supportive Care for Symptoms of Chemotherapy-Induced Oral Mucositis
Status: COMPLETED
Conditions: Oral Mucositis
Interventions: DEVICE: Chemo Mouthpiece|OTHER: Best Supportive Care only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of a Single Dose of Lamotrigine on Brain Function in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lamotrigine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Efficacy of a Home-Use Photobiomodulation Device for the Treatment of Patients With Knee Osteoarthritis: A Prospective Double Blind, Randomized, Sham-Controlled Clinical Study
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DEVICE: B-Cure laser pro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraamniotic Administrations of ER004 to Male Subjects With X-linked Hypohidrotic Ectodermal Dysplasia
Status: RECRUITING
Conditions: X-Linked Hypohidrotic Ectodermal Dysplasia (XLHED)
Interventions: BIOLOGICAL: ER004
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-modality MRI Study on Effect to Collateral Circulation and Blood Perfusion of Acute Cerebral Infarction by Human Urinary Kallidinogenase
Status: COMPLETED
Conditions: Cerebral Infarction
Interventions: DRUG: Human Urinary Kallidinogenase|DRUG: Shuxuening injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Occupational Therapy Intervention in Patients With Complex Needs to Improve Social Reintegration
Status: COMPLETED
Conditions: Rehabilitation|Occupational Therapy
Interventions: OTHER: Occupational Therapy|OTHER: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ART-2 Pilot - Driving Pressure Limited Ventilation for Patients With ARDS
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome
Interventions: OTHER: Driving pressure limited ventilation|OTHER: Conventional ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Ribavirin Dosages and Different Duration of Treatment in Combination With PegInterferon in Patients With Genotype 2 and 3 (WRITE)
Status: COMPLETED
Conditions: Chronic Hepatitis
Interventions: DRUG: Peginterferon alpha-2a + Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Dose Finding Study
Status: COMPLETED
Conditions: HIV Infections|AIDS
Interventions: DRUG: Cholecalciferol (Vit D3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pregabalin Versus Levetiracetam In Partial Seizures
Status: COMPLETED
Conditions: Partial Seizures
Interventions: DRUG: pregabalin|DRUG: levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing and Personalising Azacitidine Combination Therapy for Treating Solid Tumours QPOP and CURATE.AI
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor|Gastrointestinal Cancer|Breast Cancer
Interventions: DEVICE: QPOP|DEVICE: CURATE.AI|DRUG: Azacitidine + docetaxel|DRUG: Azacitidine + paclitaxel|DRUG: Azacitidine + irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Text4US Program
Status: TERMINATED
Conditions: Reminder Systems|Text Messaging|Urinary Dysfunction|Urinary Bladder|Behavior Change Techniques
Interventions: BEHAVIORAL: SMS Text Messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Rifampin on the Pharmacokinetics of BAY73-4506
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Regorafenib (BAY73-4506) + rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Erlotinib Hydrochloride and Onalespib Lactate in Treating Patients With Recurrent or Metastatic EGFR-Mutant Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Lung Non-Small Cell Carcinoma|Stage IV Lung Non-Small Cell Cancer AJCC v7
Interventions: DRUG: Erlotinib Hydrochloride|OTHER: Laboratory Biomarker Analysis|DRUG: Onalespib Lactate|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prostate-Specific Membrane Antigen (PSMA) PET Scans in People Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer|Prostate Neoplasm|Prostate Adenocarcinoma|Prostate Cancer Metastatic|Metastatic Prostate Cancer
Interventions: DRUG: 18F-DCFPyL-iPSMA|DRUG: 68Ga-HBED-iPSMA|DIAGNOSTIC_TEST: PET/CT scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Health Economic Trial in Adult Patients Undergoing Ileostomy Reversal MA402S23B501
Status: COMPLETED
Conditions: Retraction of Colostomy
Interventions: DRUG: Group 1 Standard of Care|DRUG: Group 2 EXPAREL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Reliability of KHQ and ICIQ-SF in Assessing Urinary Incontinence Effects in Polish Women
Status: COMPLETED
Conditions: Urinary Incontinence|Overactive Bladder|Stress Urinary Incontinence|Urge Incontinence
Interventions: DIAGNOSTIC_TEST: King's Health Questionnaire|DIAGNOSTIC_TEST: the International Consultation on Incontinence Modular Questionnaire (ICIQ-SF) Short Form
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Efficacy of PAP Therapy for Treating OSA in the Home Environment
Status: COMPLETED
Conditions: Obstructive Sleep Apnea (OSA)
Interventions: DEVICE: Positive Airway Pressure (PAP) Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention to Reduce Body Burdens of PCBs in Residents of Anniston, Alabama
Status: COMPLETED
Conditions: Toxic Effect of Other Corrosive Organic Compounds
Interventions: DRUG: olestra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Thalidomide in Pediatric Inflammatory Bowel Diseases.
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Crohn's Disease|Ulcerative Colitis
Interventions: DRUG: Thalidomide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MAGE-A3 Antigen-Specific Cancer Immunotherapeutic in Patients With Progressive Metastatic Cutaneous Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: BIOLOGICAL: GSK Biologicals' Recombinant MAGE-A3 Antigen-Specific Cancer Immunotherapeutic (ASCI) GSK1203486A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial
Status: NOT_YET_RECRUITING
Conditions: Chronic Kidney Diseases|Acute Kidney Injury|Bleeding|Surgery
Interventions: DRUG: Desmopressin Injectable Solution|DRUG: Tranexamic Acid Injectable Product|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Summative Usability Study of Ciprofloxacin Dry Powder for Inhalation Using Placebo
Status: COMPLETED
Conditions: Bronchiectasis|Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Placebo to Ciprofloxacin DPI (BAYQ3939)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: To Explore the Effectiveness of Jing-Si Herbal Tea Against Non-alcoholic Fatty Liver Disease
Status: RECRUITING
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: OTHER: Jing-Si Herbal Tea|OTHER: Placebo Jing-Si Herbal Tea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Achilles Tendon for the Treatment of Gluteus Medius Insufficiency
Status: RECRUITING
Conditions: Arthroplasty Complications|Muscle Weakness|Muscle Atrophy|Muscle Tear
Interventions: PROCEDURE: Surgical reconstruction of gluteus medius with Achilles tendon allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mycotic Antimicrobial Localized Injection for Treatment of Corneal Ulcers
Status: COMPLETED
Conditions: Corneal Ulcer|Fungal Keratitis
Interventions: DRUG: Intrastromal voriconazole|DRUG: Natamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Once-daily Highly Active Antiretroviral Treatment Regimen Administration in HIV-1 Infected Children in Burkina Faso (ANRS 12103 BURKINAME)
Status: COMPLETED
Conditions: HIV Infections|AIDS
Interventions: DRUG: Efavirenz (EFV)|DRUG: Lamivudine (3TC)|DRUG: Didanosine (ddI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Apatinib Reverses Chemotherapy-Resistance of Patients With Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Malignant Neoplasm of Stomach Stage II
Interventions: DRUG: Apatinib|DRUG: Paclitaxel-based chemotherapeutic regimens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a Method to Measure Soft Tissue Thickness Using Near Infrared Laser Light
Status: UNKNOWN
Conditions: Cranial Soft Tissue
Interventions: DEVICE: MRI scan|DEVICE: Laser scan|PROCEDURE: Dental cast creation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Benfotiamine in Alzheimer's Disease: A Pilot Study
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Benfotiamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of GC3107(BCG Vaccine) in Healthy Infants
Status: COMPLETED
Conditions: BCG Vaccination Reaction|Tuberculosis
Interventions: BIOLOGICAL: GC3107|BIOLOGICAL: Intradermal BCG SSI inj.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Corifollitropin Alfa Combined With Menotropin Versus Follitropin and Lutropin Alfa in Expected Suboptimal Responders
Status: COMPLETED
Conditions: Infertility, Female
Interventions: DRUG: Corifollitropin alfa and menotropin|DRUG: Follitropin alfa and lutropin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT