pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Combination Chemotherapy With or Without G-CSF in Treating Older Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia|Neutropenia
Interventions: BIOLOGICAL: filgrastim|DRUG: amsacrine|DRUG: carmustine|DRUG: cytarabine|DRUG: etoposide|DRUG: idarubicin|DRUG: mitoxantrone hydrochloride|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Vojta Therapy on the Motor Function of Children With Neuromotor Disorders
Status: NOT_YET_RECRUITING
Conditions: Motor Disorders
Interventions: OTHER: Vojta Therapy|OTHER: Conventional physiotherapy:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Preemptive Pharmacogenetics in Underserved Patients
Status: RECRUITING
Conditions: Use of Prescription Medications|Pharmacogenetic Testing
Interventions: DIAGNOSTIC_TEST: Panel-based pharmacogenetic genotyping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exoskeleton-assisted Training to Accelerate Walking Recovery Early After Stroke: the TARGET Phase II Study
Status: COMPLETED
Conditions: Stroke|Paresis|Gait, Hemiplegic
Interventions: BEHAVIORAL: Exoskeleton-assisted gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Talabostat and Pembrolizumab for the Treatment of Advanced Solid Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Recurrent Malignant Solid Neoplasm
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Talabostat Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: APBI Versus EBRT Therapy After Breast Conserving Surgery for Low-risk Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: RADIATION: Accelerated partial breast irradiation|RADIATION: External beam whole breast irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Amniotic Membrane Injection as An Addition to Physical Therapy in Patients With Rotator Cuff Tear
Status: COMPLETED
Conditions: Rotator Cuff Tear|Rotator Cuff Tendinopathy|Ultrasonography
Interventions: OTHER: Amniotic membrane preparation and injection (AM group)|OTHER: Physiotherapy (PT group)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sildenafil in Single Ventricle Patients
Status: COMPLETED
Conditions: Heart Disease
Interventions: DRUG: Sildenafil by injection|DRUG: Sildenafil by injection|DRUG: Sildenafil by injection|DRUG: Sildenafil by injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MK-3475 as Maintenance Therapy in Extensive Stage SCLC
Status: COMPLETED
Conditions: Extensive Stage Small Cell Lung Carcinoma
Interventions: BIOLOGICAL: Pembrolizumab|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Single, Multiple Dose and Food Effect Study of SHR2285 Tablets on Pharmacokinetics and Pharmacodynamics in Healthy Subjects
Status: COMPLETED
Conditions: Thrombosis
Interventions: DRUG: SHR2285 tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RCT of Methotrexate Added to Treatment As Usual in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder
Interventions: DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lipopolysaccharide (LPS) Challenge in Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: BIOLOGICAL: Lipopolysaccharide|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Meropenem-FL058 Phase 2 Study in the Treatment of Complicated Urinary Tract Infections
Status: UNKNOWN
Conditions: Complicated Urinary Tract Infection|Acute Pyelonephritis
Interventions: DRUG: Meropenem- FL058|DRUG: Piperacillin -tazobactam|DRUG: Saline|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Management of Blood Pressure and Cholesterol in Elderly Chinese With Hypertension and Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation|Hypertension
Interventions: DRUG: Amlodipine/Atorvastatin 5 Mg-20 Mg ORAL TABLET|DRUG: Amlodipine/Atorvastatin 5 Mg-10 Mg ORAL TABLET|DRUG: Allisartan Isoproxil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect Of An Expanded Long Term Periodization Exercise Training In Patients With Cardiovascular Disease
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Artery Disease
Interventions: OTHER: Periodized Exercise Training Regime|OTHER: Non Periodized Exercise Training Regime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Androgen Blockade Therapy on Thymus Function in Older Patients Who Have Undergone Radical Prostatectomy for Localized Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: OTHER: diagnostic laboratory biomarker analysis|OTHER: flow cytometry|OTHER: physiologic testing|PROCEDURE: computed tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: UR+AIMS Gout Wearable Skin Uric Acid Monitor Study
Status: NOT_YET_RECRUITING
Conditions: Gout
Interventions: DEVICE: Uric Acid and Metabolite Monitor System (UR+AIMS) skin patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Evaluation the Efficacy and Safety of Vardenafil in Subjects With Erectile Dysfunction for 10 Weeks
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized DC Vaccines in Non Small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Autologous dendritic cell vaccine loaded with personalized peptides (PEP-DC vaccine)|DRUG: Low dose cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Leukotriene Modifier Or Corticosteroid or Corticosteroid-Salmeterol Trial
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: fluticasone|DRUG: montelukast|DRUG: Fluticasone plus salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SITAgliptin Plus GLARgine to Glycemic Control in the Hospital Setting (SITAGLAR-H)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Sitagliptin 100mg|DRUG: Glargine|DRUG: Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conducting Clinical Trials of the Medicine "Rutan Tablets 0.1g" No. 10 in the Complex Therapy of COVID-19
Status: COMPLETED
Conditions: Patients With COVID-19
Interventions: DRUG: The drug "Rutan 0.1".|OTHER: Basic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-culprit Vessels for ST-Segment Elevation Myocardial Infarction
Status: COMPLETED
Conditions: Conservative Pharmacotherapy|Staged Percutaneous Coronary Intervention|Non-culprit Vessels|ST-Segment Elevation Myocardial Infarction
Interventions: PROCEDURE: Percutaneous coronary intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Clindamycin / Benzoyl Peroxide Gel in Subjects With Acne
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: clindamycin / benzoyl peroxide gel|DRUG: clindamycin gel|DRUG: BPO gel|DRUG: vehicle gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Off-Pump and On-Pump Techniques and Oxidative Stress in CABG Surgery
Status: COMPLETED
Conditions: Cerebral Oxygenation|Oxidative Stress|Myocardial Infarction
Interventions: PROCEDURE: On-Pump CABG|PROCEDURE: Off-Pump CABG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lume Lung 2 : BIBF 1120 Plus Pemetrexed Compared to Placebo Plus Pemetrexed in 2nd Line Nonsquamous NSCLC
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Nintedanib (BIBF1120)|DRUG: Pemetrexed|DRUG: pemetrexed|DRUG: B12|DRUG: dexamethasone (or corticosteroid equivalent)|DRUG: placebo|DRUG: dexamethasone (or corticosteroid equivalent)|DRUG: B12|DRUG: Folic Acid|DRUG: B12|DRUG: dexamethasone (or corticosteroid equivalent)|DRUG: Folic Acid|DRUG: placebo|DRUG: Folic Acid|DRUG: Nintedanib (BIBF1120)|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of GLPG1837 in Subjects With Cystic Fibrosis (S1251N Mutation)
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: GLPG1837 dose 1|DRUG: GLPG1837 dose 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Locoregional Treatment and Palbociclib in de Novo, Treatment Naive, Stage IV ER+, HER2- Breast Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer Stage IV|Radiotherapy|Surgery
Interventions: DRUG: Palbociclib|OTHER: locoregional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of the Execution of an Efficacy Trial in the Nursing Home Setting
Status: WITHDRAWN
Conditions: Partial Thickness Wounds
Interventions: DRUG: Xenaderm® Ointment|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inflammation and Vascular Function in Atherosclerosis
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DRUG: salsalate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extension to a Study on the Efficacy and Safety of Vildagliptin Compared to Rosiglitazone in Drug Naive Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Primary Unloading and Delayed Reperfusion in ST-Elevation Myocardial Infarction: The STEMI-DTU Trial
Status: RECRUITING
Conditions: ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
Interventions: DEVICE: Impella CP® placement prior to reperfusion with Primary PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application of High-dose Insulin Therapy to Improve Liver Function and Regeneration
Status: RECRUITING
Conditions: Liver Dysfunction|Liver Metastasis Colon Cancer|Liver Regeneration
Interventions: DRUG: High-Dose Insulin Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy of Self-Help Multicomponent Lifestyle Medicine Intervention and Cognitive Behavioral Therapy for Depressive Symptoms
Status: NOT_YET_RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: Lifestyle medicine|BEHAVIORAL: Cognitive behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Prehabilitation as a Strategy to Minimize Surgical Risk in Pancreatic Surgery: Efficacy and Determining Factors.
Status: UNKNOWN
Conditions: Pancreatic Neoplasms|Anesthesia
Interventions: BEHAVIORAL: Multimodal Prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Circular(Soave) and Heart-shaped Anastomosis in Hirschsprung's Disease: A Prospective Multicenter Randomized Controlled Trial
Status: RECRUITING
Conditions: Constipation
Interventions: PROCEDURE: Heart-shape anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vilazodone for the Treatment of Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: PTSD|Depression
Interventions: DRUG: Treatment (Viibryd)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acoustic Radiation Force Impulse Imaging (ARFI) : a New Technique to Assess Liver Elasticity
Status: COMPLETED
Conditions: Liver Fibrosis|Liver Cirrhosis|Viral Hepatitis|Liver Tumour|Cardiac Failure|Biliary Cholestasis.
Interventions: DEVICE: ARFI measurement|DEVICE: ARFI measurement|DEVICE: ARFI measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nasal Oxygen Therapy After Cardiac Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiac Valve Disease|Coronary Artery Disease|Respiratory Failure
Interventions: DEVICE: High Flow Nasal Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: IPV vs CPT for Airway Clearance During CF Exacerbation
Status: WITHDRAWN
Conditions: Cystic Fibrosis|Airway Clearance Impairment
Interventions: DEVICE: Intrapulmonary Percussive ventilation|DEVICE: Chest Physiotherapy Vest (Incourage)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serious Game Versus Online Course to Pre-train Medical Students on the Management of an Adult Cardiac Arrest.
Status: COMPLETED
Conditions: Education, Medical, Undergraduate|Out-of-Hospital Cardiac Arrest|Simulation Training
Interventions: OTHER: Serious Game|OTHER: Online course
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Repeated Dosing of Naproxcinod on Renal Hemodynamic and on Sodium Balance in Healthy Volunteers Before and After a Single Dose of Furosemide
Status: COMPLETED
Conditions: Renal Hemodynamics
Interventions: DRUG: naproxcinod|DRUG: Naproxen|DRUG: placebo|DRUG: furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Family Safety Net - Aim 3: Randomized Control Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Suicide|Accidental Injuries|Firearm Injury
Interventions: BEHAVIORAL: MI FSN - Lethal Means Reduction|BEHAVIORAL: Scripted FSN - Lethal Means Reduction|BEHAVIORAL: General Firearm Safety Intervention - General Firearm Safety|BEHAVIORAL: General Firearm Comparison - General Firearm Safety
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Brolucizumab in Adult Patients With Suboptimal Anatomically Controlled Neovascular Age-related Macular Degeneration
Status: COMPLETED
Conditions: Neovascular Age-Related Macular Degeneration
Interventions: DRUG: RTH258/Brolucizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amoxicillin and Metronidazole During or After the Periodontal Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Periodontitis
Interventions: PROCEDURE: Scaling and root planing|DRUG: Placebos during SRP|DRUG: Placebos after SRP|DRUG: Metronidazole during SRP|DRUG: Amoxicillin during SRP|DRUG: Metronidazole after SRP|DRUG: Amoxicillin after SRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Next Generation Vaccine Card: Innovative Technology to Improve Vaccine Equity in Rural and Urban Settings in East Africa
Status: NOT_YET_RECRUITING
Conditions: Vaccines
Interventions: OTHER: SMS reminders for upcoming vaccination(s)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Periodontal and Orthodontic Outcomes of Straight vs. Looped Fixed Retainers
Status: RECRUITING
Conditions: Orthodontic Appliance Complication|Orthodontic Appliance Design|Orthodontic Treatment
Interventions: DEVICE: V- loop Bonded Orthodontic Retainer|DEVICE: Straight Wire Retainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relaxation and Visualization Therapy for Breast Cancer Patients
Status: TERMINATED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Relaxation and Visualization Therapy|OTHER: Health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sorafenib Tosylate and Temsirolimus in Treating Patients With Recurrent Glioblastoma
Status: COMPLETED
Conditions: Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Neoplasm
Interventions: PROCEDURE: Conventional Surgery|OTHER: Laboratory Biomarker Analysis|DRUG: Sorafenib Tosylate|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FOLFOXIRI Plus Panitumumab Patients With Metastatic KRAS Wild-Type Colorectal Cancer With Liver Metastases Only
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Panitumumab|DRUG: Oxaliplatin|DRUG: Irinotecan|DRUG: Leucovorin|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug-Drug Interaction Study of the Effects of XL184 (Cabozantinib) on Rosiglitazone in Subjects With Solid Tumors
Status: COMPLETED
Conditions: Papillary Thyroid Cancer|Follicular Thyroid Cancer|Huerthle Cell Thyroid Cancer|Renal Cell Carcinoma
Interventions: DRUG: rosiglitazone|DRUG: XL184
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare QLS1128 With Placebo in Symptomatic Participants With Mild to Moderate COVID-19
Status: NOT_YET_RECRUITING
Conditions: COVID-19
Interventions: DRUG: QLS1128|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ocular Tissue Levels of 1.5% Levofloxacin Ophthalmic Solution Compared to an Active Comparator
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: 1.5% levofloxacin ophthalmic solution|DRUG: 0.5% moxifloxacin hydrochloride ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Methylnaltrexone in Opioid-Induced Constipation Patients
Status: UNKNOWN
Conditions: Opioid-induced Constipation
Interventions: DRUG: Methylnaltrexone (MNTX)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short Versus Long Interval to Ileostomy Reversal After Ileal Pouch Surgery
Status: TERMINATED
Conditions: Ulcerative Colitis|Ileal Pouch|Ileostomy - Stoma
Interventions: PROCEDURE: Early|PROCEDURE: Late
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Tomography Scan and CT Scan in Planning Radiation Therapy for Patients With Stage II or Stage III Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: PROCEDURE: computed tomography|PROCEDURE: positron emission tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Blinatumomab in High-risk B-cell Precursor Acute Lymphoblastic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia, Adult B-Cell
Interventions: DRUG: Blinatumomab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Adalimumab in Patients With Active Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: BIOLOGICAL: adalimumab (D2E7)|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Echinacea-based Supplement Does Not Improve Markers of Performance in Athletes
Status: COMPLETED
Conditions: Ineffective Erythropoiesis
Interventions: DIETARY_SUPPLEMENT: Echinacea-based dietary supplement|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: HiPED - High Dose Lucentis for Persistent Pigment Epithelial Detachments in Age-related Macular Degeneration
Status: TERMINATED
Conditions: Wet Macular Degeneration|Macular Degeneration|Retinal Pigment Epithelial Detachment
Interventions: DRUG: ranibizumab|DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Use of [18F]-DOPA in Hyperinsulinemic Hypoglycemia
Status: NO_LONGER_AVAILABLE
Conditions: Hyperinsulinemic Hypoglycemia, Persistent|Congenital Hyperinsulinism|Persistent Hyperinsulinemic Hypoglycemia of Infancy (PHHI)
Interventions: DRUG: 18 F-DOPA
Study Type: EXPANDED_ACCESS
Clinical trial: Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer
Status: RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Malignant Neoplasm in the Bone|Metastatic Prostate Carcinoma|Stage IVB Prostate Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Questionnaire Administration|DRUG: Radium Ra 223 Dichloride
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vitamin D Administration in the Nursing Home
Status: COMPLETED
Conditions: Vitamin D Deficiency|Osteoporosis
Interventions: DRUG: Vitamin D|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TORCH: A Study of Tarceva or Chemotherapy for the Treatment of Advanced Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Advanced Non-Small Cell Lung Cancer
Interventions: DRUG: erlotinib|DRUG: cisplatin|DRUG: gemcitabine|DRUG: cisplatin|DRUG: gemcitabine|DRUG: erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anlotinib Hydrochloride Combined With AP in Stage IIIB/IIIC/IV Non-squamous Non-small-cell Lung Cancer
Status: COMPLETED
Conditions: Non-squamous Non-small-cell Lung Cancer|Anlotinib
Interventions: DRUG: Anlotinib Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Balance and Fall Risk in Unilateral and Bilateral Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Arthropathy
Interventions: PROCEDURE: Total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Control Trial (RCT) of Early Palliative Care for HCC
Status: UNKNOWN
Conditions: Carcinoma, Hepatocellular
Interventions: BEHAVIORAL: Early Palliative Care/Symptom Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Research Study to See How Well CagriSema Helps People With Type 2 Diabetes and Excess Body Weight Lose Weight
Status: ACTIVE_NOT_RECRUITING
Conditions: Overweight|Obesity|Type 2 Diabetes Mellitus
Interventions: DRUG: Cagrilintide|DRUG: Semaglutide|DRUG: Placebo cagrilintide|DRUG: Placebo semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BP-C1 Monotherapy in Patients With Metastatic Breast Cancer Cancer: Estimation of Optimal Duration of Treatment
Status: COMPLETED
Conditions: Metastatic Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: BP-C1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Imaging Study of the Integrated TrueBeam-HyperSight CBCT System
Status: RECRUITING
Conditions: Head and Neck Cancer|Thoracic Cancer|Abdominal Cancer|Pelvic Cancer
Interventions: DEVICE: HyperSight imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: IV Acetaminophen as an Analgesic Adjunct
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: IV acetaminophen + 0.5 mg IV hydromorphone|DRUG: Normal saline + 0.5 mg IV hydromorphone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carvedilol + Simvastatin vs. Carvedilol Alone for Cirrhosis and Cirrhotic Cardiomyopathy and Impact on Hepatic Decompensation and Survival
Status: NOT_YET_RECRUITING
Conditions: Decompensated Cirrhosis|Cirrhotic Cardiomyopathy|Cirrhosis, Liver|Left Ventricular Diastolic Dysfunction|Acute Kidney Injury
Interventions: DRUG: Simvastatin 20mg|DRUG: Carvedilol 3.125 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double-Blind Lamictal (Lamotrigine) in Neurotic Excoriation
Status: COMPLETED
Conditions: Neurotic Excoriation|Pathologic Skin Picking|Psychogenic Excoriation|Dermatillomania
Interventions: DRUG: Lamictal (lamotrigine)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Patient Satisfaction and Chewing Efficiency Between Conventional and 3D Printed Complete Dentures.
Status: COMPLETED
Conditions: Patient Satisfaction
Interventions: OTHER: conventional complete denture|OTHER: 3D complete denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Combining Pasireotide With Aspiration Sclerotherapy to Improve Volume Reduction of Hepatic Cysts
Status: COMPLETED
Conditions: Symptomatic Dominant Liver Cyst
Interventions: DRUG: Pasireotide LAR 60 mg|PROCEDURE: Aspiration sclerotherapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Levetiracetam for Alzheimer's Disease-Associated Network Hyperexcitability
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lateral Advancement Flap Versus Classic Limberg Flap in The Treatment Of NonComplicated Pilonidal Sinus
Status: COMPLETED
Conditions: Pilonidal Sinus
Interventions: PROCEDURE: lateral advancement flap|PROCEDURE: classic Limberg flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: High-Risk Neuroblastoma Chemotherapy Without G-CSF
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: Topotecan|DRUG: Cyclophosphamide|DRUG: Cisplatin|DRUG: Etoposide|DRUG: Vincristine|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Post-market, Multi-center Feasibility Study of the BioDuct® Meniscal Repair Device
Status: TERMINATED
Conditions: Knee Meniscus Tear
Interventions: DEVICE: BioDuct Meniscal Repair Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Duloxetine (LY248686) in Participants With Chronic Low Back Pain
Status: COMPLETED
Conditions: Back Pain Lower Back Chronic
Interventions: DRUG: Duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: WiTNNess - TNNT1 Myopathy Natural History Study
Status: RECRUITING
Conditions: TNNT1-associated Myopathy|Infantile-onset Nemaline Rod Myopathy|Myopathies, Nemaline|Myopathy|Myopathy, Rod|Myopathy; Hereditary|Amish Nemaline Myopathy|Nemaline Myopathy 5|NEM5|Genetic Muscle Disease|Recessive Hereditary Disorder (Autosomal)|ANM
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: n3 PUFA and Muscle-disuse Atrophy in Older Women
Status: UNKNOWN
Conditions: Muscle Atrophy|Muscle Disuse Atrophy|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: n3 PUFA-enriched fish oil|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Photoaging Reversing After Picosecond Laser With DLA Assessed by Cellular Resolution OCT in Asian Patient With Melasma
Status: COMPLETED
Conditions: Melasma
Interventions: DEVICE: PicoSure 755nm picosecond alexandrite laser with diffractive lens|DEVICE: ApolloVue® S100 Image System|DEVICE: Cutometer® dual MPA 580|DEVICE: VISIA®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a 0.1% Tacrolimus Nasal Ointment as a Treatment for Epistaxis in Hemorrhagic Hereditary Telangiectasia (HHT)
Status: COMPLETED
Conditions: Hemorrhagic Hereditary Telangiectasia (HHT)
Interventions: DRUG: Protopic® (Tacrolimus) 0.1% ointment|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Distraction and Dental Anxiety Among Anxious Pediatric Patients
Status: COMPLETED
Conditions: Children's Dental Anxiety
Interventions: DEVICE: Virtual Reality Distraction during dental treatment of children.|OTHER: Control: watching cartoon on screen as distraction during dental treatment of children.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial of Enzastaurin (LY317615) in Combination With Carboplatin in Adults With Recurrent Gliomas
Status: COMPLETED
Conditions: Recurrent Gliomas
Interventions: DRUG: Enzastaurin (LY317615)|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Phase 2b, Study Evaluating Miricorilant in Adult Patients With Nonalcoholic Steatohepatitis/Metabolic Dysfunction-Associated Steatohepatitis (MONARCH)
Status: RECRUITING
Conditions: Nonalcoholic Steatohepatitis (NASH)|Metabolic Dysfunction-associated Steatohepatitis (MASH)
Interventions: DRUG: Miricorilant (Cohort A)|DRUG: Placebo (Cohort A)|DRUG: Miricorilant (Cohort B)|DRUG: Placebo (Cohort B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Venetoclax in Combination With Decitabine and Cedazuridine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Acute Biphenotypic Leukemia|Recurrent Acute Myeloid Leukemia|Refractory Acute Biphenotypic Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Decitabine and Cedazuridine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Corplex™ Donepezil Transdermal System Compared to Oral Aricept®
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Donepezil TDS Version A|DRUG: Donepezil TDS Version B|DRUG: Aricept|DRUG: Donepezil TDS Version D|DRUG: Donepezil TDS Version E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a Prognostic Biomarker Using Brain Diffusion MRI in X-linked Adrenoleukodystrophy
Status: NOT_YET_RECRUITING
Conditions: X-linked Adrenoleukodystrophy
Interventions: DEVICE: brainQuant module of brainTale-care platform
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Amicar Pharmacokinetics of Children Having Craniofacial Surgery
Status: COMPLETED
Conditions: Craniosynostosis
Interventions: DRUG: Epsilon-Aminocaproic Acid|DRUG: Epsilon-Aminocaproic Acid|DRUG: Epsilon-Aminocaproic Acid|DRUG: Epsilon-Aminocaproic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Romidepsin in Relapsed or Refractory Extranodal NK/T-cell Lymphoma
Status: COMPLETED
Conditions: Histologically Proven Extranodal NKTcell Lymphoma
Interventions: DRUG: Romidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Compression Stockings on the Number of Apneas/Hypopneas Per Hour of Sleep in Patients With Syndrome Obstructive Sleep Apnea/Hypopnea as Compared to no Treatment
Status: RECRUITING
Conditions: Sleep Apnea Syndromes
Interventions: DEVICE: Wearing of specific compression stockings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lifting of Gastric Tube Through Trans-substernal Versus Trans-esophageal Bed Path in MIE
Status: UNKNOWN
Conditions: Esophageal Neoplasms|Esophagectomy
Interventions: PROCEDURE: lifting of the gastric tube to the neck for gastro-esophageal anastomosis through trans-substernal or trans-esophageal bed path.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimized Programming in Spinal Cord Stimulation (SCS) System
Status: COMPLETED
Conditions: Neuropathic Pain|Pain
Interventions: DEVICE: Precision Spinal Cord Stimulation (SCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improvement of a Physically Active Lifestyle
Status: COMPLETED
Conditions: Pain|Osteoarthritis|Rheumatoid Arthritis|Heart Diseases|Diabetes Mellitus, Type 2|Behavior|Motivation
Interventions: BEHAVIORAL: Intervention Group (IG)|BEHAVIORAL: Active Control Group (ACG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Personalized, Transdiagnostic Approach to Preventative Mental Health
Status: UNKNOWN
Conditions: Mental Health|Mental Disorders|Delivery of Health Care|Self-Assessment|Diagnosis, Psychiatric
Interventions: DIAGNOSTIC_TEST: Introspect Health
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pazopanib Plus Lapatinib Compared To Lapatinib Alone In Subjects With Advanced Or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: pazopanib (GW786034) 400 mg|DRUG: lapatinib (GW572016) 1500 mg|DRUG: lapatinib (GW572016) 1000 mg|DRUG: pazopanib (GW786034) 800 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of rTMS Based on Hemodynamic Activity for Language Recovery in Early Poststroke Aphasia
Status: UNKNOWN
Conditions: Stroke|Aphasia
Interventions: DEVICE: MagPro magnetic stimulator (HF rTMS)|DEVICE: MagPro magnetic stimulator (sham)|DEVICE: MagPro magnetic stimulator (LF rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions
Status: RECRUITING
Conditions: Leiomyosarcoma|Soft-tissue Sarcomas
Interventions: DRUG: Gemcitabine|DRUG: Nab-Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RescueTEE for In-hospital Cardiac Arrest (ReTEECA Trial)
Status: WITHDRAWN
Conditions: Echocardiography, Transesophageal|In-hospital Cardiac Arrest|Cardiac Arrest|Cardiopulmonary Arrest With Successful Resuscitation|ACLS|Image Guided ACLS
Interventions: DIAGNOSTIC_TEST: Tranesophageal Echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Eradicating Barrett's Esophagus Using Radiofrequency Ablation or a Novel Hybrid Argon Plasma Coagulation Technique
Status: TERMINATED
Conditions: Barrett's Esophagus|High-grade Dysplasia in Barrett Esophagus|Low Grade Dysplasia in Barrett Esophagus
Interventions: DEVICE: Hybrid argon plasma ablation (HAPC)|DEVICE: Radiofrequency ablation (RFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Exergaming on Heart Rate, Perceived Exertion, and Technology Acceptance in Healthy Individuals
Status: COMPLETED
Conditions: Healthy|Physical Activity|Virtual Reality|Exergame|Inactivity, Physical
Interventions: DEVICE: Meta Oculus Quest 2™ Virtual Reality Exergaming
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Vitamin D3 Versus 25OHD3 on Mineral Metabolism and Immune Function
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DRUG: Vitamin D|DRUG: 25(OH)D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Virtual Reality for the Treatment of Chronic Low Back Pain
Status: WITHDRAWN
Conditions: Back Pain Lower Back Chronic
Interventions: DEVICE: HTC Vive with Karuna Virtual Reality Program|DEVICE: HTC Vive with Lumen Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment Study for Children and Adolescents With Acute Promyelocytic Leukemia
Status: RECRUITING
Conditions: Acute Promyelocytic Leukemia
Interventions: DRUG: Mylotarg|DRUG: Arsenic Trioxide|DRUG: All-trans retinoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Acetylsalicylic Acid and Ibuprofen for Tuberculosis
Status: RECRUITING
Conditions: Tuberculosis, Pulmonary|Tuberculosis, MDR|Tuberculosis Infection
Interventions: DRUG: Control group|DRUG: ASA group|DRUG: IBU group|DRUG: SoC TB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting Androgen Signaling in Urothelial Cell Carcinoma - Neoadjuvant
Status: RECRUITING
Conditions: Urothelial Carcinoma Bladder|Androgen Receptor Positive
Interventions: DRUG: Degarelix|COMBINATION_PRODUCT: Gemcitabine/Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zero-fluoroscopic Ablation Versus Conventional Fluoroscopic Ablation for the Treatment of Ventricular Arrhythmias
Status: UNKNOWN
Conditions: Ventricular Arrythmia|Ventricular Premature Complexes|Ventricular Tachycardia
Interventions: PROCEDURE: Zero-fluoroscopy ablation|PROCEDURE: Conventional fluoroscopy ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Trial of NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: NCX 470 0.065% (initial phase of trial)|DRUG: Latanoprost 0.005% (initial phase of trial)|DRUG: NCX 470 0.1% (initial phase of trial)|DRUG: NCX 470 0.1% (remainder of trial)|DRUG: Latanoprost 0.005% (remainder of trial)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Acceptance and Commitment Therapy in Primary Health Care
Status: COMPLETED
Conditions: Medical Certificates for Sick Leave and Drug Prescriptions
Interventions: BEHAVIORAL: Education with Acceptance and Commitment Therapy|OTHER: Control, no intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: UTAA06 Injection in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Relapsed/Refractory Acute Myeloid Leukemia
Interventions: BIOLOGICAL: B7-H3 target, CAR gene modified gdT cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Progressively Decreasing Titration Schedules of Bifeprunox in Subjects With Schizophrenia or Bipolar Disorder
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Bipolar Disorder
Interventions: DRUG: Bifeprunox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy for Patients With Locally Advanced Pancreatic Cancer (LAPC) With Additional Chemo-radiotherapy (CRT) for Patients With Borderline Resectable Tumours
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Oxaliplatin, irinotecan, 5-FU & leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ethanol Inhalation on COVID-19 Treatment (a Clinical Trial Study)
Status: COMPLETED
Conditions: Clinical Infection|Outcome|Morality
Interventions: DRUG: Ethanol|DRUG: Water Distilled
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Children's Automated Respiration Monitor (ChARM) for Child Pneumonia Diagnosis by Community Health Workers in Mali
Status: COMPLETED
Conditions: Acute Respiratory Infection
Interventions: DEVICE: Children's Automated Respiration Monitor (ChARM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC