pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Whether it is More Appropriate to Spray Lugol's Solution From Cervical Esophagus to Esophagogastric Junction
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: PROCEDURE: staining from cervical esophagus to esophagogastric junction|PROCEDURE: staining from esophagogastric junction to cervical esophagus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Muscle Training Induced Angiogenesis in COPD
Status: COMPLETED
Conditions: Peripheral Muscle Dysfunction|COPD
Interventions: PROCEDURE: Muscular biopsy|OTHER: 5-10 weeks sport training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Placebo-Corrected Effects of Therapeutic Dose (100 mg) and Supratherapeutic Dose (300 mg) of ITF2357 (Givinostat) and Moxifloxacin on QT/QTC Interval
Status: COMPLETED
Conditions: Duchenne and Becker Muscular Dystrophy|Polycytemia Vera
Interventions: DRUG: ITF2357 10 mg/mL|DRUG: ITF2357 10 mg/mL|DRUG: Placebo|DRUG: Moxifloxacin Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Responsiveness of Lower Airways in Adult Patients (18-60 Years) With Stable Asthma After Treatment With Ciclesonide and Fluticasone Propionate (BY9010/NL-101)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Ciclesonide|DRUG: Fluticasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Cannabinoid 2-receptor Expression in the Brain and Spine of ALS-patients Compared to Healthy Controls With PET (18F-RoSMALS)
Status: NOT_YET_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: [18F]-RoSMA-18-d6
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Cycloset® Compared With Placebo When Added to Metformin
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DRUG: Bromocriptine Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of EN3324 (Axomadol) in Subjects With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DRUG: EN3324 (axomadol)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and GEM 231 in Treating Patients With Recurrent or Refractory Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: GEM 231|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Tolerability of Rizatriptan for Long Term Treatment of Acute Migraine in Children and Adolescents (MK-0462-086 AM3)
Status: COMPLETED
Conditions: Acute Migraine With or Without Aura in Adolescents
Interventions: DRUG: rizatriptan benzoate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tele-expertise in Patients With Diabetes Hospitalized for Covid-19 Infection
Status: TERMINATED
Conditions: Diabetic Patient (Type 1,2, MODY, Secondary) or With Corticosteroid-induced Diabetes Following Initiation of Corticosteroid Treatment
Interventions: DEVICE: Continuous blind glucose measurement device (Free style Pro)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Hydroxyethyl Starch and Renal Function After Radical Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Voluven (Hydroxyethyl starch 130/0,4)|DRUG: Sodium Chloride 9 mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunogenicity and Safety of Tetravalent Dengue Vaccine (TDV) at the End of Shelf Life in Healthy Adults
Status: COMPLETED
Conditions: Dengue Fever
Interventions: BIOLOGICAL: Tetravalent Dengue Vaccine (TDV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of the Transversus Abdominus Plane (TAP) Block for Post-Cesarean Delivery Analgesia
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: ropivacaine|DRUG: saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minocycline and Celecoxib as Adjunctive Treatments of Bipolar Depression
Status: COMPLETED
Conditions: Depression|Bipolar Disorder|Bipolar Depression|Mood Disorders
Interventions: DRUG: Minocycline|DRUG: Celecoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy Following Therapeutic Autologous Lymphocytes and Cyclophosphamide in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage IV Melanoma
Interventions: DRUG: cyclophosphamide|BIOLOGICAL: aldesleukin|BIOLOGICAL: autologous tumor cell vaccine|OTHER: laboratory biomarker analysis|OTHER: immunologic technique|OTHER: immunohistochemistry staining method|GENETIC: polymerase chain reaction|BIOLOGICAL: therapeutic autologous lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subtle Energy Transmission and Tao Calligraphy Mindfulness in Telomere Length in Peripheral Blood Leukocytes
Status: ACTIVE_NOT_RECRUITING
Conditions: Telomere Length|Quality of Life
Interventions: OTHER: Mindfulness practice with Calligraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fixed Versus Weight-Based Enoxaparin Dosing in Thoracic Surgery Patients
Status: COMPLETED
Conditions: Venous Thromboembolism|Deep Venous Thrombosis|Surgery
Interventions: DRUG: Fixed Dose Enoxaparin|DRUG: Variable Dose Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Left Atrial Posterior Wall and PV Isolation Using Cryoballoon for Treatment of Persistent AF
Status: ACTIVE_NOT_RECRUITING
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: Standard Cryoballoon Pulmonary Vein Isolation (PVI)|DEVICE: Cryoballoon PVI + Posterior Wall Isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Glargine and Oral Antidiabetic Drugs (OADs) in Newly Diagnosed Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: metformin-based Oral Antidiabetic Drugs|DRUG: Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Autism
Status: UNKNOWN
Conditions: Autism|Autism Spectrum Disorder|Autistic Disorder|Autism, Akinetic|Autism; Atypical|Autism; Psychopathy|Autism Fragile Syndrome X|Autism With High Cognitive Abilities|Autism-Related Speech Delay|Autism, Susceptibility to, 6|Autism Spectrum Disorder High-Functioning|Autistic Thinking|Autism, Susceptibility to, X-Linked 6|Autistic Behavior
Interventions: OTHER: No Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Virtual Reality-based Training on Balance and Walking in Youth With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: Virtual reality active video gaming using Nintendo switch sports|BEHAVIORAL: Standard physical therapy balance exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Human Dehydrated Amnion Chorion Allograft in Laryngectomy/Pharyngectomy
Status: TERMINATED
Conditions: Larynx Cancer|Pharynx Cancer|Pharyngocutaneous Fistula
Interventions: BIOLOGICAL: Dehydrated human amnion/chorion membrane
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preventing Chemotherapy-Induced Peripheral Neuropathy With Acupuncture (PACT Trial)
Status: RECRUITING
Conditions: Acupuncture|Early-stage Breast Cancer|Chemotherapy-induced Peripheral Neuropathy|Breast Cancer Stage I|Breast Cancer Stage II|Breast Cancer Stage III
Interventions: DEVICE: Acupuncture|OTHER: Nature scenery with a relaxation exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Scandinavian Bell's Palsy Study
Status: COMPLETED
Conditions: Bell's Palsy
Interventions: DRUG: Prednisolone + placebo|DRUG: Valaciclovir + placebo|DRUG: Prednisolone + valaciclovir|DRUG: Placebo + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liposomal Vincristine Plus Dexamethasone in Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Vincristine Sulfate Liposomes Injection|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Alendronate on the Immune Response to Hepatitis B Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Hepatitis B
Interventions: DRUG: Alendronate|DRUG: Hepatitis B Vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Adult Alveolar Soft-part Sarcoma|Adult Angiosarcoma|Adult Epithelioid Sarcoma|Adult Extraskeletal Chondrosarcoma|Adult Extraskeletal Osteosarcoma|Adult Fibrosarcoma|Adult Leiomyosarcoma|Adult Liposarcoma|Adult Malignant Fibrous Histiocytoma|Adult Malignant Hemangiopericytoma|Adult Malignant Mesenchymoma|Adult Neurofibrosarcoma|Adult Rhabdomyosarcoma|Adult Synovial Sarcoma|Gastrointestinal Stromal Tumor|Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Recurrent Adult Soft Tissue Sarcoma|Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Stage III Adult Soft Tissue Sarcoma|Stage IV Adult Soft Tissue Sarcoma
Interventions: DRUG: romidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clomiphene Citrate (CC) Co-treatment With HP Urinary FSH vs HP Urinary FSH in CC-resistant PCOS
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Step-up HP u FSH|DRUG: Clomiphine citrate plus low dose uFSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expectancy as Alternative to Treatment for Cervical Intraepithelial Neoplasia Grade 2 Among Women 25 - 30 Years of Age
Status: COMPLETED
Conditions: CIN2|Therapy
Interventions: PROCEDURE: Expectancy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sphenopalatine Ganglion Blocks RCT
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Lidocaine|DRUG: Bupivacaine|DRUG: Ropivacaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Electrical Stimulation in ICU Patients
Status: TERMINATED
Conditions: Intensive Care Unit Acquired Weakness
Interventions: OTHER: Neuromuscular Electrical Stimulation - NMES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fate at Long-term of Mild to Moderate Bicuspid Aortic Valve Disease Left Untreated at the Time of Supracoronary Ascending Aorta Replacement
Status: COMPLETED
Conditions: Bicuspid Aortic Valve|Ascending Aorta Aneurysm
Interventions: PROCEDURE: Ascending aorta replacement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Carbetocin Versus Oxytocin and Ergometrine for the Prevention of Postpartum Hemorrhage
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: DRUG: Carbetocin|DRUG: oxytocin|DRUG: ergometrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Underlying Mechanisms Regarding the Effect of Glucagon on the Kidneys Will be Investigated in Healthy Males.
Status: RECRUITING
Conditions: Kidney Diseases
Interventions: OTHER: Glucagon|OTHER: Placebo|OTHER: Glucagon and exendin 9-39
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Twice-daily Measurement of Expired CO During Hospitalization on Smoking
Status: TERMINATED
Conditions: Hospitalization|Smoking
Interventions: OTHER: Twice-daily expired carbon monoxide (CO) measurements|OTHER: Minimal control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modification of Scleral Suture Fixation of Dislocated IOL
Status: COMPLETED
Conditions: Dislocated Intraocular Lens
Interventions: PROCEDURE: Intraocular lens (IOL) ab externo scleral suture fixation|PROCEDURE: Modified IOL ab externo scleral suture fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Response Study of Dexamethasone in Combination With Bupivacaine 0.25%
Status: COMPLETED
Conditions: Post Surgical Pain
Interventions: DRUG: Bupivacaine 0.25%|DRUG: Dexamethasone|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Eucrisa for Atopic Dermatitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Mild to Moderate Atopic Dermatitis
Interventions: BEHAVIORAL: Online Treatment response|DRUG: EUCRISA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Exercise-induced Glycemic Variations and Hybrid Closed-loop Systems
Status: RECRUITING
Conditions: Type 1 Diabetes|Exercise
Interventions: BEHAVIORAL: Moderate intensity exercise|BEHAVIORAL: High intensity interval exercise|BEHAVIORAL: Combined exercise|BEHAVIORAL: Resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of 'Vascular Competence' Profile and Endothelial Activation in the Hemolytic Uremic Syndrome in Children and Adults
Status: COMPLETED
Conditions: Hemolytic Uremic Syndrome
Interventions: BIOLOGICAL: Extra blood draw samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Can Acupoint Low Intensity Shockwave Therapy Improve Bladder Voiding Efficiency
Status: RECRUITING
Conditions: Detrusor Underactivity
Interventions: PROCEDURE: Low Intensity Shockwave Therapy (LiSWT)|DRUG: Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Osteopathic Treatment in Pain and Functionality Individuals With Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: PROCEDURE: Osteopathic manipulative treatment|PROCEDURE: Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Administration of Trastuzumab (Herceptin) by a Single-use Injection Device Versus a Handheld Syringe
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: trastuzumab [Herceptin]|DRUG: trastuzumab [Herceptin]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of 0.1% Uracil Topical Cream (UTC) for the Prevention of Hand-Foot Syndrome
Status: COMPLETED
Conditions: Palmar-Plantar Erythrodysesthesia|Breast Cancer
Interventions: DRUG: Cream|DRUG: 0.1% Uracil Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Arm Boot Camp Study: Evaluation of a Program to Increase Upper Limb Recovery After Stroke
Status: COMPLETED
Conditions: Stroke|Cerebral Infarction|Brain Diseases|Central Nervous System Diseases|Cerebrovascular Disorders|Brain Ischemia|Brain Infarction|Vascular Diseases|Infarction|Nervous System Diseases|Cardiovascular Diseases
Interventions: BEHAVIORAL: Arm Boot Camp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Ultrasound Assessment of Parasternal Intercostal Muscle Thickness During Weaning From Mechanical Ventilation
Status: UNKNOWN
Conditions: Parasternal Intercostal Muscle Thickness|Weaning From Mechanical Ventilation
Interventions: DIAGNOSTIC_TEST: Parasternal intercostal muscles thickness ultrasound indicies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Study of Spectrum of Sleep Disorders in Cirrhotic Patients and the Efficacy of Zolpidem in Cirrhotic Patients With Insomnia
Status: COMPLETED
Conditions: Cirrhosis
Interventions: DRUG: Zolpidem|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetic Study of EVP-6124 in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Central Nervous System Diseases
Interventions: DRUG: EVP-6124 (0.3 mg/day)|DRUG: EVP-6124 (1.0 mg/day)|DRUG: Placebo|DRUG: Antipsychotic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fraction Dose Escalation of Hypo-fractionated Radiotherapy in LANSCLC
Status: COMPLETED
Conditions: Locally Advanced Lung Carcinoma
Interventions: RADIATION: Hypofractionated radiotherapy|DRUG: Concurrent chemotherapy|DRUG: Consolidation immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vorinostat and Azacitidine in Treating Patients With Locally Recurrent or Metastatic Nasopharyngeal Cancer or Nasal Natural Killer T-Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult Nasal Type Extranodal NK/T-Cell Lymphoma|Recurrent Nasopharyngeal Keratinizing Squamous Cell Carcinoma|Recurrent Nasopharyngeal Undifferentiated Carcinoma|Stage IV Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7|Stage IV Nasopharyngeal Undifferentiated Carcinoma AJCC v7
Interventions: DRUG: Azacitidine|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Balding Scalp Including 12-month Follow-up
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: LEO 43204 gel|DRUG: Vehicle gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Behavioral Dysfunctions and Related Neuronal Correlates in Patients With Dystonia
Status: RECRUITING
Conditions: Dystonia|Neurologic Disorder|NEUROSCIENCE
Interventions: BEHAVIORAL: control group|BEHAVIORAL: experimental group|DIAGNOSTIC_TEST: EEG power in alpha band
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate the Long-Term Efficacy, Safety, and Tolerability of Repeated Administration of Upadacitinib (ABT-494) in Participants With Crohn's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Crohn's Disease (CD)
Interventions: DRUG: ABT-494
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2b, Study of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)
Status: ACTIVE_NOT_RECRUITING
Conditions: Thyroid Eye Disease|Graves Orbitopathy|Endocrine System Diseases|Eye Diseases|Thyroid Associated Ophthalmopathy|Graves Ophthalmopathy|Thyroid Diseases|Orbital Diseases|Proptosis|IGF1R|Exophthalmos|Hashimoto
Interventions: DRUG: Linsitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Bioavailability of Rocatinlimab Autoinjector and Vial in Healthy Participants
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: Rocatinlimab|DRUG: Rocatinlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mapping Electrogram Morphology Recurrence for Atrial Fibrillation Ablation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Electrogram Morphology Mapping (EMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Smartphone Based Optical Diagnostic Tool for Neonatal Jaundice
Status: COMPLETED
Conditions: Jaundice, Neonatal|Hyperbilirubinemia, Neonatal
Interventions: DEVICE: bilirubin concentration estimation from smartphone pictures|PROCEDURE: bilirubin concentration measured in standard blood samples|DEVICE: bilirubin concentration measured by transcutaneous device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Optic Edge Design in a Silicone Intraocular Lens on Posterior Capsule Opacification
Status: COMPLETED
Conditions: Cataract|Pseudophakia
Interventions: DEVICE: Cataract surgery with implantation of an intraocular lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Consent Forms in Cancer Research: Examining the Effect of Length on Readability
Status: COMPLETED
Conditions: Cancer
Interventions: OTHER: 6,000 word consent form|OTHER: 4,000 word consent form|OTHER: 2,000 word consent form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Long-Term Study of Gabapentin Enacarbil (GEn, XP13512) vs. Placebo in Patients With Restless Legs Syndrome.
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: GEn (XP13512)|DRUG: GEn (XP13512)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of Computer-assisted X-ray Diagnosis and Other Triage Tools to Optimise Xpert Orientated Community-based Active Case Finding for TB and COVID-19
Status: RECRUITING
Conditions: Tuberculosis|COVID-19|HIV Infections
Interventions: DIAGNOSTIC_TEST: CAD|DIAGNOSTIC_TEST: Xpert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study of Efficacy and Safety of NIS793 (With and Without Spartalizumab) in Combination With SOC Chemotherapy in First-line Metastatic Pancreatic Ductal Adenocarcinoma (mPDAC)
Status: TERMINATED
Conditions: Metastatic Pancreatic Ductal Adenocarcinoma
Interventions: BIOLOGICAL: NIS793|BIOLOGICAL: Spartalizumab|DRUG: gemcitabine|DRUG: nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Comparing TACE With TACE + SABR in Stage BCLC B HCC (HepSTAR)
Status: TERMINATED
Conditions: Liver Neoplasms|Hepatocellular Cancer
Interventions: PROCEDURE: Trans-arterial Chemo-Embolization|DRUG: Doxorubicin|RADIATION: Stereotactic Ablative Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Vasopressin Modulates Neural Responses to Looming Visual Stimuli: An Eye-tracking Study
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: Vasopressin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Magnetoencephalographic (MEG) Evidence for Novel Metaphor Processing Among Schizophrenic Patients
Status: COMPLETED
Conditions: Schizophrenia|Novel Metaphor
Interventions: DEVICE: Magnetoencephalograph (MEG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sotagliflozin in Heart Failure With Preserved Ejection Fraction (HFpEF) Patients
Status: RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: Sotagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safinamide for Multiple System Atrophy (MSA)
Status: COMPLETED
Conditions: Multiple System Atrophy
Interventions: DRUG: Safinamide Methanesulfonate|DRUG: Safinamide Methanesulfonate matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy &Safety of Methylphenidate Transdermal System (MTS) in Adolescents Aged 13-17 Years With ADHD
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: methylphenidate transdermal system|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Rechallenge With Sunitinib in Metastatic Pancreatic Neuroendocrine Tumor Previously Failed to Sunitinib
Status: COMPLETED
Conditions: Pancreatic Neuroendocrine Tumour Metastatic
Interventions: DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flow Rates of High-flow Nasal Cannula and Extubation Outcome
Status: COMPLETED
Conditions: Hypoxemic Respiratory Failure
Interventions: OTHER: Flow rate setting of high-flow nasal cannula (initially 60L/min)|OTHER: Flow rate setting of high-flow nasal cannula (initially 40L/min)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treating Cancer-Related Fatigue Through Systematic Light Exposure (Light for Fatigue Study)
Status: COMPLETED
Conditions: Multiple Myeloma|Fatigue
Interventions: DEVICE: AYO light glasses (Experimental)|DEVICE: AYO light glasses (Comparator)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of PG2 in Patients With Advanced Pharyngeal or Laryngeal Squamous Cell Carcinoma Under Concurrent Chemoradiotherapy
Status: TERMINATED
Conditions: Cancer-related Fatigue
Interventions: DRUG: Astragalus polysaccharides 500 mg|DRUG: Placebo|PROCEDURE: Concurrent chemoradiotherapy with PUL (cisplatin/tegafur plus uracil (UFT)/leucovorin) every 2 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-centre Randomized Double Blind 52-week Study to Assess the Safety of QVA149 Compared to QAB149 in Patients With COPD Who Have Moderate to Severe Airflow Limitation
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: QVA149|DRUG: QVA149|DRUG: QAB149|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Immobilization in the Postoperative Analgesia of Surgically Treated Distal Radius Fractures
Status: COMPLETED
Conditions: Radius Fracture Distal
Interventions: PROCEDURE: No immobilization|PROCEDURE: Volar splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Daratumumab Plus Lenalidomide Versus Lenalidomide Alone as Maintenance Treatment in Participants With Newly Diagnosed Multiple Myeloma Who Are Minimal Residual Disease Positive After Frontline Autologous Stem Cell Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dyspnea and Cardiotoxicity in Multiple Myeloma Patients Who Receive Carfilzomib
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma|Shortness of Breath|Dyspnea|Cardiotoxicity
Interventions: DEVICE: EndoPAT|DEVICE: Blood Pressure Cuff|DIAGNOSTIC_TEST: Echocardiogram|OTHER: Quality of Life Assessment|OTHER: Blood Tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment on Effects of Tongjiang Granule in Treating Nonerosive Reflux Disease Overlapping Epigastric Pain Syndrome
Status: RECRUITING
Conditions: Gastroesophageal Reflux|Functional Dysphonia
Interventions: DRUG: Tongjiang granule|DRUG: Tongjiang granule simulant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Virtual Reality on Perioperative Pediatric Anxiety
Status: UNKNOWN
Conditions: Preoperative Anxiety|Maladaptive Postoperative Behavior|Emergence Delirium
Interventions: DEVICE: Virtual Reality glasses|PROCEDURE: standard perioperative care without virtual reality program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study On The Effect Of Propolis And Dentine Bonding Agent In Treating Dentine Hypersensitivity
Status: COMPLETED
Conditions: Dentine Hypersensitivity
Interventions: DRUG: Dentin-Bonding Agents|DRUG: Propolis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Online vs. Face-to-face Nutritional Advice in Kuwait (EatWellQ8)
Status: COMPLETED
Conditions: Dietary Modification|Dietary Habits
Interventions: BEHAVIORAL: Non-personalised advice|BEHAVIORAL: Online personalised advice|BEHAVIORAL: Face-to-face personalised advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Empaglifozin in Early Diabetic Kidney Disease
Status: WITHDRAWN
Conditions: Diabetic Kidney Disease|Diabetes Mellitus Type 2
Interventions: DRUG: Empagliflozin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Fluticasone Propionate Reduce the Late Allergic Reaction When the Drug is Given Post-allergen?
Status: COMPLETED
Conditions: Mild Intermittent Asthma
Interventions: DRUG: Fluticasone propionate (Flovent Diskus) 250 mcg|DRUG: budesonide 400 mcg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase Ib Study of Radium Ra 223 Dichloride in Combination With Paclitaxel in Cancer Subjects With Bone Lesions
Status: COMPLETED
Conditions: Neoplasms|Bone Diseases
Interventions: DRUG: Radium Ra 223 dichloride (Xofigo, BAY88-8223)|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Phase I, Multicenter, Dose Escalation Study of DCR-MYC in Patients With Solid Tumors, Multiple Myeloma, or Lymphoma
Status: TERMINATED
Conditions: Solid Tumors|Multiple Myeloma|Non-Hodgkins Lymphoma|Pancreatic Neuroendocrine Tumors|PNET|NHL
Interventions: DRUG: DCR-MYC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of CROCUVIS+® on Computer Vision Syndrome, Sleep and Mood Disorders
Status: COMPLETED
Conditions: Computer Vision Syndrome|Sleep Disorder|Mood Disorders
Interventions: DIETARY_SUPPLEMENT: Saffron extract (Crocus sativus)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: High-intensity Training in Patients With Spondyloarthritis: a Randomized Controlled Trial
Status: RECRUITING
Conditions: Axial Spondyloarthritis
Interventions: BEHAVIORAL: High intensity interval training (HIIT)|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pulmonary Rehabilitation in Hematopoietic Stem Cell Transplantation Recipients
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplantation
Interventions: OTHER: Exercise training group|OTHER: Control training group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Effects of Exercise Training and AGE-crosslink Breaker on Cardiovascular Structure and Function
Status: COMPLETED
Conditions: Cardiovascular Disease|Aging|Endothelial Dysfunction|Physical Activity
Interventions: DRUG: Alt-711|BEHAVIORAL: Physical exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Domestic Violence Intervention to Reduce Psychological Distress and Violence Among Women Experiencing IPV in Nepal
Status: ACTIVE_NOT_RECRUITING
Conditions: Intimate Partner Violence|Domestic Violence|Intervention|Mental Health|Secondary Prevention|Problem Management Plus|Cluster Randomized Trial
Interventions: BEHAVIORAL: DeVI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy Study of Glucagonlike Peptide-1 to Treat Reperfusion Injury
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: DRUG: liraglutide (Novo Nordisk, Bagsværd, Denmark)|DRUG: liraglutide placebo (Novo Nordisk)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Performance of 1 Day Multifocal Contact Lenses
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: Lens A|DEVICE: Lens B|DEVICE: Habitual Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The TRAfermin in Neuropathic Diabetic Foot Ulcer Study - Southern Europe The TRANS-South Study
Status: COMPLETED
Conditions: Diabetic Foot Ulcer of Neuropathic Origin
Interventions: DRUG: Trafermin 0.01% spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Candesartan Versus Propranolol for Migraine Prevention
Status: COMPLETED
Conditions: Migraine Without Aura|Migraine With Aura|Chronic Migraine
Interventions: DRUG: Candesartan|DRUG: propranolol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combined 650 nm and Infrared Laser on Chronic Diabetic Foot Ulcer Surface Area:
Status: COMPLETED
Conditions: Diabetic Foot|Wound Heal
Interventions: DEVICE: laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study With Licroca Depot, a Controlled Release Product, Injected Into the Prostate
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: 2-hydroxyflutamide (2-HOF) [Liproca Depot]|DRUG: 2-Hydroxyflutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of 4-Hydroxytamoxifen (4-OHT) Gel in Women Aimed at Reducing Dense Breast Tissue
Status: TERMINATED
Conditions: Mammographic Breast Density
Interventions: DRUG: 4-OH tamoxifen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate and Mid-term Effect of a Natural Topical Product in Patients With Musculoskeletal Pain
Status: COMPLETED
Conditions: Musculoskeletal Pain|Chronic Pain|Joint Pain|Stiffness of Unspecified Joint, Not Elsewhere Classified
Interventions: OTHER: Placebo|OTHER: Fisiocrem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Train New Examiners Via Modified Gingival Margin Plaque
Status: COMPLETED
Conditions: Dental Plaque
Interventions: DRUG: Fluoride|DRUG: Triclosan/Fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine as an Augmentation Strategy for Electroconvulsive Therapy (ECT) in Depression
Status: COMPLETED
Conditions: Unipolar Depression|Bipolar Depression
Interventions: DRUG: Ketamine|DRUG: Methohexital
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Glucose Clamp Study of Wockhardt's Insulin Human Regular for Injection and Novolin R, in Healthy Subjects.
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: BIOLOGICAL: Wosulin R|BIOLOGICAL: Novolin R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Proof-of-principle Study of HBO-SRS for Brain Metastases
Status: COMPLETED
Conditions: Brain Metastases
Interventions: DEVICE: Hyperbaric oxygen given at 2.4 ATA for 30 minutes immediately prior to SRS - HBOT for 30 minutes - SRS without prior HBO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cough Capture as a Portal Into the Lung
Status: RECRUITING
Conditions: Lung Diseases|Lung Cancer|Lung Diseases, Obstructive|Lung Diseases, Interstitial|Lung Inflammation
Interventions: OTHER: Observational only, all subjects; measure DNA mutation and proteomic survey.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of a Craniosacral Therapy Protocol in the Treatment of Infant Colic
Status: COMPLETED
Conditions: Infant Conditions|Colic, Infantile|Gastro-Intestinal Disorder
Interventions: OTHER: Manual treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effectiveness of Aflibercept in Routine Clinical Practice in Patients With Diabetic Macular Oedema
Status: COMPLETED
Conditions: Macular Edema
Interventions: DRUG: Eylea (Aflibercept, VEGF Trap-Eye, BAY86-5321)|DRUG: Anti-VEGF therapies including: Eylea Aflibercept, VEGF Trap-Eye, BAY86-5321) and Ophthalmologicals / Antineovascularisation agents (S01LA05)|DRUG: Anti-VEGF therapies including: Eylea Aflibercept, VEGF Trap-Eye, BAY86-5321) and Ophthalmologicals / Antineovascularisation agents (S01LA05)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing the Effect of Deep Neck Flexors Versus MCkenice Exercises on Cervical Functions
Status: UNKNOWN
Conditions: Chronic Neck Pain
Interventions: OTHER: traditional therapeutic exercises|OTHER: traditional therapeutic exercises and McKenize technique|OTHER: traditional therapeutic exercises and deep neck flexor exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Evaluate the Prevention and Safety of Doxorubicin-induced Cardiomyopathy Using Extracorporeal Shock Waves
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DEVICE: Extracorporeal shock waves
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Outpatient Radical Prostatectomy - Surgical and Anesthetic Considerations
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: PROCEDURE: patient discharge on postoperative day 2|PROCEDURE: patient discharge on postoperative day 1|PROCEDURE: patient discharge in the day of surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Health Improvement of Obese Patients After Fecal Microbiota Transplantation (FMT)
Status: COMPLETED
Conditions: Obesity; Familial
Interventions: OTHER: Fecal microbiota
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Factors Associated With CPC 1-2 in 110 Patients Admitted in French ICU for a Myocardial Infarction Complicated by an OHCA.
Status: UNKNOWN
Conditions: Out-Of-Hospital Cardiac Arrest|Myocardial Infarction|Coma|Outcome, Fatal|Neurologic Dysfunction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Single and Multiple Ascending Dose Study With AZD9164 Given for 13 Days in Healthy Male and Female Japanese Subjects
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: AZD9164|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Conduction System Pacing Versus Biventricular Pacing After Atrioventricular Node Ablation
Status: RECRUITING
Conditions: Heart Failure|Tachycardia-induced Cardiomyopathy|Atrial Fibrillation
Interventions: DEVICE: Biventricular pacemaker implantation|DEVICE: Conduction system pacing device implantation|PROCEDURE: AV node ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Pharmacokinetics, Safety and Tolerability of Single and Multiple Intravenous Doses of N-acetylcysteine (NAC) in Chinese Healthy Volunteers
Status: COMPLETED
Conditions: Respiratory Tract Disorders
Interventions: DRUG: N-acetylcysteine (NAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bevacizumab After Chemoradiotherapy For Locally Advanced Lung Adenocarcinoma
Status: COMPLETED
Conditions: Lung Adenocarcinoma
Interventions: DRUG: Bevacizumab|RADIATION: chest radiation|DRUG: concurrent chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT