pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Growth Hormone in Chronically Ill Children
Status: WITHDRAWN
Conditions: Hurler Syndrome|Cerebral Palsy|Juvenile Rheumatoid Arthritis|Crohn Disease|HIV Infections
Interventions: DRUG: Growth Hormone|PROCEDURE: Whole body Protein turnover|PROCEDURE: DEXA scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotics Against Amyloid Angiopathy
Status: RECRUITING
Conditions: Cerebral Amyloid Angiopathy
Interventions: DRUG: Minocycline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of a Reproductive Life Planning Tool at the Pediatric Well-Baby Visit With Postpartum Women
Status: COMPLETED
Conditions: Postpartum Period|Contraception Behavior|Women's Health|Primary Health Care
Interventions: BEHAVIORAL: RLPT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of EzVision® Videolaryngoscope and Gum Elastic Bougie-Assisted Machintosh Laryngoscopy
Status: RECRUITING
Conditions: Intubation; Difficult or Failed|Airway Complication of Anesthesia
Interventions: DEVICE: EzVision® videolaryngoscopy|DEVICE: Macintosh Blade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Cinacalcet in the Control of Primary Hyperparathyroidism
Status: COMPLETED
Conditions: Hyperparathyroidism, Primary|Osteoporosis
Interventions: DRUG: cinacalcet|DRUG: Alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Non-Invasive SpHb and PVI Monitoring on Intra-Operative and Post-Surgical Clinical Outcomes
Status: TERMINATED
Conditions: Surgery
Interventions: DEVICE: In vivo SpHb and PVi Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of Three Body Positioning Strategies in the Drainage Fluids After Coronary Artery Bypass Surgery
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: OTHER: Bed Rotation Group|OTHER: Orthostatic Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Application of Sticky Bone and Bio-Oss Collagen in Alveolar Ridge Preservation
Status: RECRUITING
Conditions: Alveolar Bone Resorption
Interventions: PROCEDURE: alveolar ridge preservation with bio-oss collagen|PROCEDURE: alveolar ridge preservation with sticky bone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Quality of Life Benefits of ACUVUE® Theravision® With Ketotifen in Subjects With Ocular Allergies
Status: WITHDRAWN
Conditions: Ocular Physiology
Interventions: DEVICE: TEST Lens|DEVICE: CONTROL Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Efficacy and Safety of Apomivir®
Status: UNKNOWN
Conditions: Influenza
Interventions: DRUG: Apomivir®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRC
Status: COMPLETED
Conditions: Neurological Disorders|Cerebral Malaria|Bacterial Meningitis|Central Nervous System Tuberculosis|Neurosyphilis|Cryptococcal Meningitis
Interventions: DEVICE: Immunochromatographic HAT tests (DSD)|DEVICE: Card Agglutination Trypanosoma Test|DEVICE: TB POC Nucleic Acid Amplification Test (Molbio Diagnostics)|DEVICE: TB 3-marker RDT (Tulip diagnostics)|DEVICE: Cryptococcal Antigen Lateral Flow Assay (Immy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Milvexian Using an IV Microtracer With Additional Formulation and Food Effect Comparison in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BMS-986177 Oral Solution|DRUG: [14C]BMS-986177 Solution for Infusion|DRUG: BMS-986177 Spray-dried Dispersion Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Baloxavir Versus Oseltamivir for Nursing Home Influenza Outbreaks
Status: ACTIVE_NOT_RECRUITING
Conditions: Influenza|Influenza, Human|Influenza -Like Illness
Interventions: DRUG: Oseltamivir|DRUG: Baloxavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Reiki on Breastfeeding Self-efficacy, Pregnancy Complaints and Quality of Life
Status: NOT_YET_RECRUITING
Conditions: Obstetric Complication
Interventions: OTHER: Reiki implementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acute Effect of a Proprietary Botanical Blend Rich in Polyphenols on Flow-mediated Dilation in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Memophenol 300 mg|DIETARY_SUPPLEMENT: Memophenol 600 mg|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Tranexamic Acid for Alloplastic Breast Reconstruction
Status: UNKNOWN
Conditions: Hematoma Postoperative|Breast Cancer|Tranexamic Acid
Interventions: DRUG: Tranexamic acid|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Closed-Loop O2 Use During High Flow Oxygen Treatment Of Critical Care Adult Patients (CLOUDHFOT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Hypoxemic Respiratory Failure|Acute Hypercapnic Respiratory Failure|Respiratory Depression|Respiratory Failure
Interventions: DEVICE: Closed-loop FiO2 controller|DEVICE: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Rabies Vaccine（Human Diploid Cell）for Human Use,Freeze-dried in a Population Aged 10-60 Years
Status: ACTIVE_NOT_RECRUITING
Conditions: Rabies
Interventions: BIOLOGICAL: Rabies Vaccine（Human Diploid Cell）for Human Use,Freeze-dried
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacodynamic Outcomes in CCS Patients Treated With an Individualized Treatment Strategy
Status: RECRUITING
Conditions: Coronary Artery Disease|Platelet Reactivity
Interventions: DRUG: CYP2C19 genotype guided P2Y12 monotherapy|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parent's Satisfaction and Evaluation of Postsurgical Outcomes in Unilateral Cleft Lip / Palate Newly Born Infants With / Without Vacuum Formed Nasoalveolar Molding Aligners : A Controlled Clinical Trial
Status: UNKNOWN
Conditions: Cleft Lip and Palate
Interventions: DEVICE: Vacuum formed aligners
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Subcutaneous Versus Intravenous ACZ885 in Adult Patients With Established Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: ACZ885|DRUG: ACZ885|DRUG: ACZ885|DRUG: ACZ885
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of BLS_ILB_E710c for the Fertile Women With Cervical Intraepithelial Neoplasia(CIN3)
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia
Interventions: DRUG: BLS_ILS_E710c 500mg|DRUG: BLS_ILB_710c 1000mg|DRUG: BLS_ILS_E710c 1500mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sevoflurane Concentration on Intraocular Pressure in Surgical Children With Healthy Eyes
Status: UNKNOWN
Conditions: Intraocular Pressure
Interventions: OTHER: concentration profile 1|OTHER: concentration profile 2|OTHER: concentration profile 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy/Safety of Urogynecology Synthetic Mesh Surgery
Status: RECRUITING
Conditions: Pelvic Organ Prolapse|Stage III and IV High Grade Pelvic Organ Prolapse
Interventions: PROCEDURE: Urodynamic investigations before and after a mesh surgery protocol.|PROCEDURE: Urodynamic investigations before and after a robotic-assisted sacrocolpopexy protocol.|PROCEDURE: Urodynamic investigations before and after a hysterectomy with trans-vaginal mesh repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ACCESS 2: AI for pediatriC diabetiC Eye examS Study 2
Status: RECRUITING
Conditions: Type 1 Diabetes|Type 2 Diabetes|Cystic Fibrosis-related Diabetes
Interventions: DIAGNOSTIC_TEST: Point of Care Autonomous AI diabetic retinopathy exam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Multiprofen-CC™ to Reduce Pain After Total Knee Arthroplasty
Status: NOT_YET_RECRUITING
Conditions: Postsurgical Pain
Interventions: DRUG: Multiprofen-CC™ plus standard treatment|OTHER: Placebo plus standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects on Insulin Resistance With Tadalafil in Type 2 Diabetes - a Double-blind, Placebo-controlled Crossover Study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Tadalafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Distal Transradial Access for Primary Percutaneous Coronary Intervention in STEMI Patients
Status: UNKNOWN
Conditions: Acute ST-segment Elevation Myocardial Infarction|Radial Artery Occlusion|Distal Radial Artery Approach
Interventions: PROCEDURE: Arterial access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase III Long-Term Extension Study With Dexpramipexole
Status: ENROLLING_BY_INVITATION
Conditions: Eosinophilic Asthma
Interventions: DRUG: Dexpramipexole Dihydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Assess the Efficacy and Safety of the Combination of a Drug Call Quizartinib With Chemotherapy (FLAG-IDA) in Patients With Acute Myeloid Leukemia That Has Not Responded to the First Treatment or That Has Returned After the First Treatment
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Quizartinib|DRUG: Fludarabine|DRUG: Cytarabine|DRUG: Idarubicin|DRUG: glycosylated G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiodynamic Therapy (RDT) With Gliolan in Patients With First Recurrence of Brain Tumor
Status: RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: Gliolan|RADIATION: Radiodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Cardiac Lesions Angiogenesis by 68Ga-NODAGA-RGD Cardiac PET
Status: TERMINATED
Conditions: Myocardial Infarction, Acute|Myocardial Reperfusion|Chronic Ischemic Heart Disease
Interventions: OTHER: 68Ga-NODAGA-RGD PET/CT|DIAGNOSTIC_TEST: 82-Rb PET/CT as part of standard care, not a comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Inspiratory Muscle Training and Breathing Exercises Combined With Upper Extremity and Trunk in Patients With Sarcoidosis
Status: COMPLETED
Conditions: Pulmonary Sarcoidosis
Interventions: DEVICE: Threshold IMT|OTHER: breathing exercises combined with upper extremity and trunk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effects of Interpectoral-Pectoserratus Plane Block After Breast Cancer Surgery
Status: NOT_YET_RECRUITING
Conditions: Pain, Postoperative|Disability Physical|Quality of Life
Interventions: OTHER: Preoperative Interpectoral - Pectoserratus Plane Block|OTHER: Intraoperative Interpectoral - Pectoserratus Plane Block|OTHER: Non Block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine in Adults 18 Years of Age or Older With Renal Transplant
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Herpes Zoster vaccine GSK1437173A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors
Status: RECRUITING
Conditions: Metastatic Malignant Solid Neoplasm|Recurrent Malignant Solid Neoplasm|Recurrent Platinum-Resistant Ovarian Carcinoma|Refractory Ovarian Carcinoma
Interventions: DRUG: BET Bromodomain Inhibitor ZEN-3694|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|BIOLOGICAL: Ipilimumab|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Nivolumab|PROCEDURE: Positron Emission Tomography|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rhBMP-2 Versus Autograft in Critical Size Tibial Defects
Status: TERMINATED
Conditions: Tibial Fractures
Interventions: DEVICE: recombinant bone morphogenetic protein 2|PROCEDURE: Autogenous iliac crest bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RESCUE Study - Everolimus in Liver Transplantation Recipients With Renal Insufficiency
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DRUG: Everolimus|DRUG: Calcineurin inhibitors (CNI)|DRUG: Mycophenolate acid (MPA)/ Azathioprine (AZA)|DRUG: Steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oregano Ointment vs. Standard Treatment for Pediatric Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DRUG: Oregano extract cream|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prognostic Impact of Anatomical Resection Vs. Non-anatomical Resection for HCC
Status: UNKNOWN
Conditions: Patients Affected by Hepatocellular Carcinoma|Disease-Free Survival|Overall Survival
Interventions: PROCEDURE: anatomical liver resection|PROCEDURE: Non-anatomical liver resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intradialytic Electrical Muscle Stimulation and Passive Leg Mobilisation on Blood Pressure and Dialysis Efficacy
Status: COMPLETED
Conditions: Hypotension
Interventions: DEVICE: transcutaneous muscle stimulation, treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Probiotics on the Clinical Outcomes and Gut Microenvironment in Patients With Fatty Liver
Status: UNKNOWN
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: (Microbial cell preparation) Probiotics|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab With or Without TRC105 in Treating Patients With Metastatic Kidney Cancer
Status: COMPLETED
Conditions: Clear Cell Renal Cell Carcinoma|Recurrent Renal Cell Carcinoma|Stage IV Renal Cell Cancer|Type 1 Papillary Renal Cell Carcinoma|Type 2 Papillary Renal Cell Carcinoma
Interventions: BIOLOGICAL: Anti-Endoglin Chimeric Monoclonal Antibody TRC105|BIOLOGICAL: Bevacizumab|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Fluzoparib Combined With Camrelizumab in Germline BRCA-mutated HER2-negative Breast Cancer
Status: ENROLLING_BY_INVITATION
Conditions: Germline BRCA-mutated HER2-negative Breast Cancer
Interventions: DRUG: Camrelizumab+Fluzoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Characterize the Abuse Liability of ALO-02 in Healthy, Non-Dependent, Recreational Opioid Users When ALO-02 Capsules Are Crushed and Snorted
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ALO-02 weight-matched placebo|DRUG: crushed ALO-02 30 mg/3.6 mg|DRUG: oxycodone weight-matched placebo|DRUG: crushed oxycodone IR 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Efficacy and Safety of Tacrolimus in Treated Refractory Focal Segmental Glomerulosclerosis
Status: TERMINATED
Conditions: FSGS
Interventions: DRUG: FK506|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Intravitreal hI-con1™ in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration
Status: COMPLETED
Conditions: Choroidal Neovascularization|Age-related Macular Degeneration
Interventions: BIOLOGICAL: hI-con1|BIOLOGICAL: ranibizumab|OTHER: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blade vs Screw Intertrochanteric Hip Fracture Fixation Study
Status: WITHDRAWN
Conditions: Pertrochanteric Fracture of Femur, Closed
Interventions: DEVICE: Lag screw fixation|DEVICE: Helical blade fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breath and Air Stacking on Respiratory Mechanics in Tracheostomized Patients
Status: COMPLETED
Conditions: Mechanical Ventilation|Lung Infection
Interventions: PROCEDURE: Breath Stacking|PROCEDURE: Air Stacking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Autologous Bone Marrow Mesenchymal Stem Cells in the Treatment of Patients With Amyotrophic Lateral Sclerosis
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: OTHER: Biological: Cell-based therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a mHealth Application as a Family Supportive Tool in Pediatric Otolaryngology Perioperative Process
Status: RECRUITING
Conditions: TONSILLECTOMY
Interventions: OTHER: M-HEALTH APP|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Part A: Drug Interaction Study of Sofosbuvir and Antiretroviral Therapy (ART) Combinations in HIV and Hepatitis C Virus (HCV) Co-infected Patients. Part B: Efficacy and Safety of Sofosbuvir for 12 Weeks in HIV/HCV Co-infected Patients.
Status: COMPLETED
Conditions: Hepatitis C|HIV
Interventions: DRUG: SOF|DRUG: EFV/FTC/TDF|DRUG: EFV|DRUG: ZDV/3TC|DRUG: ATV|DRUG: Ritonavir|DRUG: FTC/TDF|DRUG: DRV|DRUG: RAL|DRUG: PEG|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of 2 Standard Doses of Bevacizumab in Combination With Chemotherapy in Epithelial Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer|Platinum-resistant Ovarian Cancer
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oblimersen and Gemtuzumab Ozogamicin in Treating Older Patients With Relapsed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: oblimersen sodium|DRUG: gemtuzumab ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Machine learnINg for the rElapse Risk eValuation in Acute Biliary Pancreatitis.
Status: NOT_YET_RECRUITING
Conditions: Acute Pancreatitis|Pancreatitis Due to Gallstones|Pancreatitis Biliary|Pancreatitis Relapsing
Interventions: DIAGNOSTIC_TEST: MINERVA Machine Learning model
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Limb Remote Ischemic Preconditioning for Prevention of Delirium in Elderly Patients After Non-cardiac Surgery
Status: UNKNOWN
Conditions: Elderly Patients|Non-cardiac Surgery
Interventions: PROCEDURE: limb remote ischemic preconditioning(LRIP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection FR BL Cohort
Status: TERMINATED
Conditions: COVID-19|Lymphocytopenia
Interventions: DRUG: Interleukin-7|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised, Comparing Fixed Doses of Pramipexole to Investigate the Efficacy and Safety in Patients With RLS.
Status: COMPLETED
Conditions: Idiopathic Restless Legs Syndrome
Interventions: DRUG: Pramipexole 0.125 mg tablet|DRUG: Pramipexole 0.5 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of a Biological Implant to Reinforce Overlapping Sphincter Repair Versus Overlapping Sphincter Repair Alone
Status: TERMINATED
Conditions: Fecal Incontinence|Anal Incontinence
Interventions: DEVICE: Biodesign Tissue Repair Graft|OTHER: Overlapping Sphincter Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetes Self-Management Education (DSME) and Its Effect on Clinical, Psychosocial, and Behavioral Outcomes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Effectiveness of an intensified DSME in T2D adult patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial to Assess the Safety, Tolerability, and Pharmacokinetics of the Anti-Orthopoxvirus Compound Tecovirimat
Status: COMPLETED
Conditions: Smallpox
Interventions: DRUG: tecovirimat|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Physical Activity as a Coadjuvant Treatment in the Healing of Venous Ulcers in Primary Health Care.
Status: COMPLETED
Conditions: Varicose Ulcer
Interventions: BEHAVIORAL: Project active legs|PROCEDURE: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics/Pharmacodynamics of Albiglutide
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BIOLOGICAL: albiglutide (GSK716155)|BIOLOGICAL: albiglutide (GSK716155)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Galilei Lens Professional vs. Predicate Devices: a Comparison Study
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Galilei Lens Professional|DEVICE: IOLMaster|DEVICE: Lenstar
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Probiotics: Clinical Intervention Trial in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DIETARY_SUPPLEMENT: Lactobacillus acidophilus|DIETARY_SUPPLEMENT: Lactobacillus Rhamnosus GG ®|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Assessment of Urinary Antiseptics Methenamine and Methylthioninium in Recurrent Cystitis
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DRUG: Methenamine + Methylthioninium|DRUG: Methenamine + Methylthioninium + Acriflavine + Atropa belladona|DRUG: Antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Associations Between the Oral and Intestinal Icrobiome and Neovascular Age-related Macular Degeneration
Status: RECRUITING
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: Probiotic Combination Cap/Tab|DRUG: intravitreal Anti-VEGF injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chemotherapy or Observation in Stage I-II Intermediate or High Risk Endometrial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Cancer
Interventions: DRUG: carboplatin and paclitaxel|OTHER: observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of Vaginal Suppository WO3191 in the Post-treatment of Bacterial Vaginosis
Status: COMPLETED
Conditions: Vaginosis, Bacterial
Interventions: OTHER: Medical Device: WO3191|OTHER: Medical Device: Vagisan® Lactic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trauma-Informed Guilt Reduction Therapy Compared to Prolonged Exposure
Status: NOT_YET_RECRUITING
Conditions: Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Trauma Informed Guilt Reduction Therapy|BEHAVIORAL: Prolonged Exposure Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Jinzhen Oral Liquid in Treating Children With COVID-19 Infection
Status: UNKNOWN
Conditions: COVID-19|Child, Only
Interventions: DRUG: Jinzhen oral liquid or Jinhuaqinggan granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Surgical Facemask With the Double-trunk Mask on Oxygenation in COVID-19
Status: COMPLETED
Conditions: Covid19|Hypoxemia
Interventions: OTHER: Standard Oxygen Delivery System|OTHER: Double-Trunk Mask|OTHER: Surgical Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open-label Milnacipran for Persistent Knee Pain One Year After Total Knee Arthroplasty (TKA)
Status: COMPLETED
Conditions: Knee Pain After Total Knee Arthroplasty|Osteoarthritis Pain
Interventions: DRUG: Open-label flexibly dosed milnacipran
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study of the Predictability of Levemir® in Terms of Metabolic Control, Change of Body Weight and Hypos
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin detemir|DRUG: insulin aspart|DRUG: human soluble insulin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating Pegfilgrastim and a Multi-Day Topotecan Regimen in Subjects With Relapsed or Refractory Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: OTHER: PI Discretion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Duloxetine vs Placebo in Treatment of Binge Eating Disorder With Depression
Status: COMPLETED
Conditions: Binge Eating|Depression
Interventions: DRUG: Duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Tofacitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Perioperative Fluid Therapy in Pediatric Patients Undergoing Penile Hypospadias Repair
Status: COMPLETED
Conditions: Volume Overload
Interventions: DIAGNOSTIC_TEST: lung ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Preventing Toxicity in Renal Cancer Patients Treated With Immunotherapy Using Fecal Microbiota Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alcohol Withdrawal Syndrome Treated With Adjunctive Phenobarbital or Ketamine
Status: WITHDRAWN
Conditions: Alcohol Withdrawal Syndrome
Interventions: DRUG: Ketamine|DRUG: Phenobarbital|DRUG: Lorazepam|DRUG: Placebo A|DRUG: Placebo B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Impact of Ice Application on the Venous Puncture Pain in the Pediatric Population
Status: NOT_YET_RECRUITING
Conditions: Venous Puncture Pain
Interventions: OTHER: ice application|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of IBE-814 Intravitreal (IVT) Implant - A Sustained, Low Dose Dexamethasone Therapy
Status: COMPLETED
Conditions: Diabetic Macular Oedema|Retinal Vein Occlusion With Macular Oedema
Interventions: DRUG: IBE-814 70ug|DRUG: IBE-814 140ug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 2-part Study to Assess Local Tolerability, Safety and Pharmacokinetics of Ceftaroline in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 600 mg ceftaroline fosamil in 50 ml infusion volume|DRUG: Placebo in 50 ml infusion volume|DRUG: 600 ceftaroline fosamil in 250 ml infusion volume|DRUG: Placebo in 250 ml infusion volume|DRUG: 600 mg ceftaroline in 100 ml infusion volume|DRUG: Placebo in 100 ml infusion volume
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Omega-3 Fatty Acid in the Prevention of Migraine
Status: COMPLETED
Conditions: Migraine|Omega-3 Polyunsaturated Fatty Acids
Interventions: DIETARY_SUPPLEMENT: Omega-3 polyunsaturated fatty acids|DIETARY_SUPPLEMENT: omega-6 PUFAs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Vitamin A Supplementation on Immune System in Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DIETARY_SUPPLEMENT: Vitamin A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adenoma Detection Rate With a New Pediatric Colonoscope With a Short Turn Radius (Pentax Retroview) Compared With a Standard Pentax Pediatric Colonoscope
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DEVICE: Conventional Pediatric Colonoscope|DEVICE: Short-Turn Radius Colonoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study of TQB2450 Injection Combined With Chemotherapy or Anlotinib Hydrochloride Capsule in the Treatment of Non Small Cell Lung Cancer
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: TQB2450 injection + Chemotherapy|DRUG: TQB2450 injection + Anlotinib Hydrochloride Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess Cobicistat Boosted Venetoclax in Combination With Azacitidine in Adult Patients With Newly Diagnosed AML
Status: RECRUITING
Conditions: AML, Adult
Interventions: DRUG: azacitidine|DRUG: Venetoclax|DRUG: Cobicistat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of the Effectiveness of Rehabilitation Tools for Neurovisual Disorders in Patients With Posterior Cortical Atrophy
Status: COMPLETED
Conditions: Posterior Cortical Atrophy
Interventions: BEHAVIORAL: Recognition of objects|BEHAVIORAL: Location of objects|BEHAVIORAL: Manipulation of objects
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Nitrate in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DIETARY_SUPPLEMENT: Nitrate rich beverage|DIETARY_SUPPLEMENT: Nitrate free beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1 (Ph1), Single Dose (SD), GSK961081 Absorption, Distribution, Metabolism, and Excretion (ADME) Study in Healthy Subjects
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: [14C]-GSK961081 solution for IV infusion|DRUG: [14C]-GSK961081 oral solution|DRUG: GSK961081 dry powder for inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical Pain Control With Ropivacaine by Atomized Delivery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Intraperitoneal Ropivacaine (AIR)|DRUG: Atomized Intraperitoneal Saline (AIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Study Of The 24-Hour Intraocular Pressure Lowering And Systemic Exposure Of PF-04217329
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: PF-04217329|DRUG: latanoprost vehicle|DRUG: PF-04217329|DRUG: latanoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Caldolor (Intravenous Ibuprofen) in Hospitalized Adult and Pediatric Burn Patients
Status: COMPLETED
Conditions: Burns
Interventions: DRUG: Caldolor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cook Enforcer Post-Market Study
Status: COMPLETED
Conditions: End-Stage Renal Disease
Interventions: DEVICE: Cook Advance® Enforcer 35 Focal-Force Percutaneous Transluminal Angioplasty (PTA) Balloon Catheter|DEVICE: Conventional angioplasty balloon catheters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Upstream High Bolus Dose of Tirofiban in Primary PCI for the Patients With STEMI on Short Term Outcome
Status: UNKNOWN
Conditions: High Bolus Dose of Tirofiban
Interventions: DRUG: -Administration of tirofiban (25 ug/kg bolus and 0.15 ug/kg/min maintenance infusion)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Maintenance Ipilimumab + Nivolumab Post Induction Chemotherapy + SBRT for First Line Treatment Stage IV Pancreatic Cancer
Status: RECRUITING
Conditions: Stage IV Pancreatic Cancer
Interventions: DRUG: Nivolumab|DRUG: ipilimumab|RADIATION: Stereotactic body radiation therapy|RADIATION: Low dose irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Classification and Interventional Therapy for Coronary Artery Ectasia
Status: UNKNOWN
Conditions: Coronary Artery Ectasia
Interventions: DEVICE: Single BMS|DEVICE: Single or Double BMS|DEVICE: Single or Double BMS|DEVICE: BMS+DES
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Fospropofol in Adult Laparoscopic Surgery: A Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Drug Safety
Interventions: DRUG: Fospropofol|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Bioequivalence Study of Wockhardt's Insulin Analogue Listro Mix 50/50® and Humalog Mix50/50® in Healthy Subjects
Status: WITHDRAWN
Conditions: Bioequivalence in Healthy Subjects
Interventions: BIOLOGICAL: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intraoperative and Postoperative Outcomes of Three Ophthalmic Viscosurgical Devices During Phacoemulsification
Status: COMPLETED
Conditions: Intraoperative Performance and Postoperative Outcomes Following Cataract Surgery
Interventions: PROCEDURE: Microcoaxial Phacoemulsification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Osteopathic Manual Medicine Treatment in Autism
Status: COMPLETED
Conditions: Autism Spectrum Disorders
Interventions: OTHER: Sham OMM|OTHER: Osteopathic Manual Medicine (Body Therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Socheongryong-tang and Yeongyopaedok-san in Upper Respiratory Tract Infection
Status: COMPLETED
Conditions: Upper Respiratory Tract Infections
Interventions: DRUG: SCRT|DRUG: YPS|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerance of a Partly Fermented Infant Formula With Prebiotic Oligosaccharides in Healthy Infants
Status: UNKNOWN
Conditions: Growth
Interventions: OTHER: Infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Amantadine on Traumatic Brain Injury
Status: COMPLETED
Conditions: Trauma, Brain
Interventions: DRUG: Amantadine (100mg) as add on therapy.|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stimulating Engagement in Daily and Physical Activities Among Older Adults Receiving Homecare Services (Part of Basic Care Revisited)
Status: COMPLETED
Conditions: Community-dwelling Older Adults
Interventions: BEHAVIORAL: Stay Active at Home|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smart Taiko-Drum Playing for Older Adults With Cognitive Frailty
Status: RECRUITING
Conditions: Cognitive Impairment|Frailty
Interventions: BEHAVIORAL: Smart Taiko Drumming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: End-tidal Carbon Dioxide Monitoring in Low Tidal Volume Ventilation
Status: COMPLETED
Conditions: Ventilation|End-Tidal Carbon Dioxide
Interventions: OTHER: if the ventilation parameter caused desaturation or hypercapnia we will change the parameter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Dexmedetomidine for Suprascapular Nerve Block With Axillary Nerve Block
Status: COMPLETED
Conditions: Suprascapular Nerve Block|Axillary Nerve Block|Dexmedetomidine|Arthroscopic Rotator Cuff Repair|Postoperative Pain|Pain Related Cytokine
Interventions: DRUG: Dexmedetomidine injection|DRUG: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of rTMS and tDCS on Motor Function in Stroke
Status: COMPLETED
Conditions: Stroke|Motor Function
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)|DEVICE: Transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PD-0332991, 5-FU, and Oxaliplatin for Advanced Solid Tumor Malignancies
Status: UNKNOWN
Conditions: Advanced Solid Tumor Malignancies
Interventions: DRUG: PD-0332991|DRUG: 5-FU|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of TEPSO® Socks in Improving Palmoplantar Pustulosis
Status: TERMINATED
Conditions: Pustulosis of Palms and Soles
Interventions: DEVICE: TEPSO cloth|DEVICE: Standard cloth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive-Behavioral and Physical Activity Interventions for Binge Eating and Overweight
Status: TERMINATED
Conditions: Binge-Eating Disorder|Binge Eating|Overweight and Obesity
Interventions: BEHAVIORAL: Cognitive-Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PACESETTER: Program to Avoid Cerebrovascular Events Through Systematic Electronic Tracking and Tailoring of an Eminent Risk-factor
Status: COMPLETED
Conditions: Blood Pressure|Hypertension|Mhealth
Interventions: DEVICE: PACESETTER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Henagliflozin Delays the Progress of Diabetic Nephropathy Via Regulates Gut-Renal Axis
Status: NOT_YET_RECRUITING
Conditions: Diabetic Nephropathies
Interventions: DRUG: Henagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE