pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Open-Label Surufatinib in European Patients With NET
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Tumours|Neuroendocrine Tumour of the Lung|Small Intestinal NET
Interventions: DRUG: Surufatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing a Paclitaxel Eluting Stent With Biodegradable Polymer Versus a Bare Metal Stent
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Bare Metal Stent|DEVICE: Drug Eluting Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cost-Effectiveness Analysis of a Rehabilitation Protocol With FES Cycling in Persons With Complete SCI
Status: COMPLETED
Conditions: FESD|Rehabilitation|Spinal Cord Injuries|Complete Spinal Cord Injury
Interventions: DEVICE: FES-C|OTHER: Standard Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iressa Expanded Access Program (EAP)
Status: COMPLETED
Conditions: Carcinoma|Non-small-cell Lung|Metastases|Neoplasm
Interventions: DRUG: ZD1839 (Gefitinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety and Clinical Effect of Nexagon® as a Topical Treatment for Subjects With a Diabetic Foot Ulcer (DUNE)
Status: COMPLETED
Conditions: Diabetic Foot Ulcers
Interventions: DRUG: Nexagon® Low Dose|DRUG: Nexagon® Medium Dose|DRUG: Nexagon® High Dose|DRUG: Nexagon® vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Slow-speed Traditional Resistance Training, High-speed Resistance Training and Multicomponent Training With Variable Resistances on Molecular, Body Composition, Neuromuscular, Physical Function and Quality of Life Variables in Older Adults.
Status: COMPLETED
Conditions: Aging
Interventions: OTHER: Slow-speed traditional resistance training|OTHER: High-speed resistance training|OTHER: Multicomponent training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Comparability Study in Healthy Participants - PF-06881894 On-Body Injector Relative to Prefilled Syringe
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: COMBINATION_PRODUCT: PF-06881894 by on-body injector|COMBINATION_PRODUCT: PF-06881894 by prefilled syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Magrolimab Monotherapy or Magrolimab in Combination With Azacitidine in Participants With Hematological Malignancies
Status: TERMINATED
Conditions: Hematological Malignancies
Interventions: DRUG: Magrolimab|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ixekizumab in Patients With Refractory Guttate Psoriasis
Status: NOT_YET_RECRUITING
Conditions: Guttate Psoriasis
Interventions: BIOLOGICAL: Ixekizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Inhaled Mometasone/Formoterol Versus Inhaled Fluticasone/Salmeterol in Asthma Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Inhaled Mometasone/formoterol|DRUG: Inhaled Fluticasone/Salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Comparing Treatment of Relapsing-Remitting Multiple Sclerosis (RR-MS) With Two Doses of Glatiramer Acetate (GA).
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: Glatiramer Acetate (GA) 40 mg|DRUG: glatiramer acetate 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Postpartum Contraceptive Implant Placement and Breastfeeding Success in Women at Risk for Low Milk Supply: A Non-inferiority Trial
Status: COMPLETED
Conditions: Contraception|Breastfeeding|Postpartum Contraception
Interventions: DEVICE: Etonogestrel Contraceptive Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BI 655130 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 655130 (spesolimab)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to a Bird Flu Virus Vaccine (H9N2) in Healthy Adults (Study A)
Status: COMPLETED
Conditions: Influenza|Virus Diseases
Interventions: BIOLOGICAL: H9N2 (6-2) AA ca Reassortant (A/chicken/Hong Kong/G9/97 x A/Ann Arbor/6/60 ca)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Botulinum Toxin Type A in Patients With Bladder Pain Syndrome/Intersticial Cystitis and Hunners' Lesions
Status: UNKNOWN
Conditions: Interstitial Cystitis
Interventions: PROCEDURE: intratrigonal injection of botulinum toxin|PROCEDURE: cystoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Ventilation vs. Standard Therapy for Children Hospitalized With an Acute Exacerbation of Asthma
Status: UNKNOWN
Conditions: Asthma Acute|Asthma in Children
Interventions: DEVICE: BiPAP|DEVICE: CPAP|DRUG: Ipratropium|DRUG: Magnesium Sulfate|DRUG: Aminophylline|DRUG: Standard steroid dose, hourly salbutamol, oxygen as needed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INFANT HEALTH- Promoting Mental Health and Healthy Weight in Infancy Through Sensitive Parenting
Status: ACTIVE_NOT_RECRUITING
Conditions: Infant Mental Health|Parenting|Parent-Child Relations
Interventions: BEHAVIORAL: VIPP-PUF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Physical Therapy for Pain Relief in Footballers With Muscle Injuries: a Prospective Study
Status: COMPLETED
Conditions: Athletic Injuries|Physical Therapies
Interventions: OTHER: Cryoultrasound therapy plus high-intensity laser therapy|OTHER: diathermy plus high-intensity laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Treatment of Partial Anomalous Pulmonary Venous Drainage
Status: NOT_YET_RECRUITING
Conditions: Partial Anomalous Pulmonary Venous Connection
Interventions: DEVICE: Endovascular pulmonary artery flow-limiting covered stent implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 2 Study to Evaluate the Safety and Efficacy of Intravenously Administered Benralizumab (MEDI-563).
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: Placebo|BIOLOGICAL: Benralizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Electrical Pudendal Nerve Stimulation and Tolterodine Tartrate for Urgency-Frequency Syndrome in Women
Status: COMPLETED
Conditions: Urgency-frequency Syndrome
Interventions: BEHAVIORAL: EPNS|DRUG: TT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Protein and Prebiotic Fiber Intake on Adiposity in Overweight and Obese Adults
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Protein|DIETARY_SUPPLEMENT: Prebiotic fiber|DIETARY_SUPPLEMENT: Protein plus prebiotic fiber|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting GABA-A for the Treatment of Social Disability in Young Adults With Autism Spectrum Disorders: A Phase II Proof of Mechanism Trial
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: AZD7325|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Metformin Added to Clomiphene Citrate on Pregnancy Rates in Hyperandrogenic, Chronic Oligoovulatory or Anovulatory Women
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Anovulation|Oligoovulation|Infertility|Hyperandrogenism
Interventions: DRUG: Metformin|DRUG: Clomiphene citrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Use of Silodosin to Treat Moderate to Severe Abacterial Chronic Prostatitis/Chronic Pelvic Pain Syndrome.
Status: COMPLETED
Conditions: Abacterial Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Interventions: DRUG: Silodosin 8 mg|DRUG: Placebo|DRUG: Silodosin 4 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Removal of Cytokines in Patients Undergoing Cardiac Surgery With CPB
Status: UNKNOWN
Conditions: Extracorporeal Circulation|Hemofiltration
Interventions: DEVICE: Cytosorb Adsorber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Ascending Doses of MMV390048 in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: MMV390048 5mg|DRUG: MMV390048 20mg|DRUG: MMV390048 40mg|DRUG: MMV390048 80mg|DRUG: MMV390048 120mg|DRUG: Placebo to match MMV390048
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MS-275 and Azacitidine in Treating Patients With Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Chronic Myelomonocytic Leukemia|de Novo Myelodysplastic Syndrome|Leukemia|Myelodysplastic Syndrome|Recurrent Adult Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Secondary Myelodysplastic Syndrome
Interventions: DRUG: Azacitidine|DRUG: Entinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of the Candidate Vaccine C4-V3 Alone or With Interleukin-12 (IL-12) in HIV-Infected Patients Receiving Effective Anti-HIV Drug Therapy
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Interleukin-12|BIOLOGICAL: HIV-1 C4-V3 Polyvalent Peptide Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Non-invasive Biomarker Discovery for Pre-cervical or/and Cervical Cancer--ACTN4 and Other Biomarkers in Menstrual Blood
Status: RECRUITING
Conditions: Cervical Cancer|CIN
Interventions: DEVICE: Special sanitary pad
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study to Assess the Effect of BMS-791325 on the Pharmacokinetics of Midazolam in Healthy Subjects
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Midazolam|DRUG: BMS-791325
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Cannabidiol for Fibromyalgia (The CANNFIB Trial)
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Cannabidiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Imatinib in Subjects With Seasonal Allergic Rhinitis and Who Are Sensitive to Timothy Grass Pollen
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Food Stimuli on the Calorie Restriction Response in Healthy Subjects
Status: COMPLETED
Conditions: Calorie Restriction|Aging
Interventions: OTHER: Stimuli of food smell and vision|OTHER: No stimuli of food smell and vision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pivotal Study in VAP Suspected or Confirmed to be Due to Pseudomonas Aeruginosa
Status: TERMINATED
Conditions: Pneumonia
Interventions: DRUG: Murepavadin|DRUG: Two anti-pseudomonal antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Volume Plasma Exchange Versus Standard Medical Treatment in Patients With Acute Liver Failure
Status: COMPLETED
Conditions: Acute Liver Failure
Interventions: BIOLOGICAL: Plasma Exchange|OTHER: Management of cerebral edema/intracranial hypertension:|OTHER: Transfer to Intensive Care Unit|DRUG: Prophylactic Antibiotics|OTHER: Intubation of trachea|OTHER: Administration of mannitol or 3% saline for severe elevation of Intra Cranial Pressure|OTHER: Volume Replacement|OTHER: Pressor Support|DRUG: N-acetyl-L-cysteine|OTHER: Correction of metabolic parameters|DIETARY_SUPPLEMENT: Correction of nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Pharmacokinetic Study Of Gabapentin In Japanese Subjects With Renal Impairment Including Hemodialysis
Status: TERMINATED
Conditions: PK Properties Of Gabapentin In Subjects With Impaired Renal Function
Interventions: DRUG: Gabapentin|DRUG: Gabapentin|DRUG: Gabapentin|DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Patient Preference Between Zosano Pharma Parathyroid Hormone (ZP-PTH) Patch and Forteo Pen
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: ZP-PTH|DRUG: FORTEO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Chloroquine for Influenza Prevention Trial
Status: UNKNOWN
Conditions: Influenza
Interventions: DRUG: Chloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigating Salt Taste Threshold in Patients Being Investigated for Primary Hyperaldosteronism Before and After Treatment.
Status: WITHDRAWN
Conditions: Hyperaldosteronism; Primary|Hypertension|Salt; Excess|Appetite Disorders
Interventions: PROCEDURE: adrenalectomy|DRUG: Aldosterone Antagonist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Development of Kinect-assisted Home-based Bilateral Arm Training Program for Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Conventional bilateral arm training|OTHER: Kinect-based bilateral arm training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Model-based Dose Versus Empirical Dose of Piperacillin/Tazobactam in Preterm Neonates With Late-onset Sepsis.
Status: RECRUITING
Conditions: Late-Onset Neonatal Sepsis
Interventions: DRUG: Piperacillin/tazobactam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Flonoltinib Maleate Tablets in the Treatment of Severe Novel Coronavirus (COVID-19) Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: DRUG: SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of THC on Alcohol Consumption and Neural Correlates of Reward
Status: RECRUITING
Conditions: Cannabis Use Disorder
Interventions: DRUG: Dronabinol Pill|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Virtual Coaching to Maximize Dementia Caregivers' Respite Time Use
Status: COMPLETED
Conditions: Anxiety|Burden, Dependency|Caregiver
Interventions: BEHAVIORAL: Time for Living and Caring (TLC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Status of Surgical Resection and Histologic Subtype as Predictors of Local Recurrence in Retroperitoneal Liposarcoma
Status: COMPLETED
Conditions: Liposarcoma of Soft Tissue|Surgical Procedure, Unspecified
Interventions: PROCEDURE: Retroperitoneal Liposarcoma resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial Evaluating Acutrak Headless Compression Screw Fixation of Medial Malleolus Fractures
Status: TERMINATED
Conditions: Medial Malleolus Fractures
Interventions: DEVICE: Fixation by Acutrak headless screw|DEVICE: Fixation by headed screws, plates, and or wires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kick Out Parkinson's Disease 2
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Karate Classes|BEHAVIORAL: Pre-Intervention Study Visit|BEHAVIORAL: Bimonthly Online Survey|BEHAVIORAL: 6-month Study Visit|BEHAVIORAL: 12-month Study Visit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stress Response in Opioid Use Disorder
Status: COMPLETED
Conditions: Opioid-use Disorder
Interventions: BEHAVIORAL: Psychoeducational Control|BEHAVIORAL: Affect Regulation|BEHAVIORAL: Affect Labelling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Incentives for Oklahoma Tobacco Helpline Engagement in Persistent Poverty Counties
Status: COMPLETED
Conditions: Cigarette Smoking|Nicotine Dependence
Interventions: BEHAVIORAL: Coaching calls|DRUG: Nicotine replacement therapy|BEHAVIORAL: Financial Incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect and Safety of Hemodialysis and Hemoperfusion on Severe Renal Osteopathy and Itching in Uremia Patients
Status: COMPLETED
Conditions: Hyperparathyroidism|Refractory Pruritus|Ostalgia|Insomnia
Interventions: OTHER: hemodialysis only|OTHER: hemodialysis plus hemoperfusion(HA330)|OTHER: hemodialysis plus hemoperfusion(HA130)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Classic Paroxysmal Nocturnal Hemoglobinuria
Status: UNKNOWN
Conditions: Paroxysmal Nocturnal Hemoglobinuria|Hemoglobinuria|Hemoglobinuria, Paroxysmal|Proteinuria|Urination Disorders|Thrombosis|Bone Marrow Failure|Aplastic Anemia,|Anemia, Hemolytic
Interventions: DRUG: Levamisole+cyclosporin A+Glucocorticoids|DRUG: cyclosporin A+Glucocorticoids|DRUG: Glucocorticoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the "NICU Clinical Decision Support Dashboard" - MHSB
Status: WITHDRAWN
Conditions: Preterm Birth|Low; Birthweight, Extremely (999 Grams or Less)|Neonatal Infection|Satisfaction|Stress|Chronic Lung Disease|Growth Acceleration|Adverse Event
Interventions: DEVICE: NICU Dashboard
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Multi-center, Open Label, Extension Study of ALN-VSP02 in Cancer Patients Who Have Responded to ALN-VSP02 Treatment
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: ALN-VSP02
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motor Control Exercises Versus a General Exercise Program in Patients With Nonspecific Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Non-specific lumbar exercise group|OTHER: motor control lumbar exercises|OTHER: motor control lumbar exercises with ultrasound echography feedack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Bed up Head Elevated Intubation Position With Glidescope Assisted Tracheal Intubation
Status: COMPLETED
Conditions: Bed up Head Elevated Intubation Position
Interventions: PROCEDURE: Tracheal intubation|DEVICE: Glidescope assisted tracheal intubation|DEVICE: Bed up head elevated tracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerance Following Peanut Oral Immunotherapy
Status: COMPLETED
Conditions: Peanut Allergy
Interventions: DRUG: Peanut Flour|DRUG: Oat Flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Arsenic Trioxide, Ascorbic Acid, Dexamethasone, and Thalidomide in Treating Patients With Multiple Myeloma
Status: WITHDRAWN
Conditions: Stage I Multiple Myeloma|Stage II Multiple Myeloma|Stage III Multiple Myeloma|Refractory Plasma Cell Neoplasm
Interventions: DRUG: arsenic trioxide|DRUG: ascorbic acid|DRUG: dexamethasone|DRUG: thalidomide|PROCEDURE: anti-cytokine therapy|PROCEDURE: antiangiogenesis therapy|PROCEDURE: biological therapy|PROCEDURE: chemotherapy|PROCEDURE: drug resistance inhibition|PROCEDURE: growth factor antagonist therapy|PROCEDURE: non-specific immune-modulator therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Gastric Bypass Surgery on Energy Metabolism
Status: COMPLETED
Conditions: Obesity
Interventions: PROCEDURE: Roux-en-Y gastric bypass surgery|DIETARY_SUPPLEMENT: low calorie diet (1,000 kcal/day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fasting Study of Albuterol Sulfate Extended-Release Tablets 8 mg and VoSpire® ER Tablets 8 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: albuterol sulfate extended-release 8 mg tablets|DRUG: VoSpire™ ER 8 mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Safety And Tolerability Of Lixisenatide In Monotherapy In Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: lixisenatide AVE0010
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of e-Cigarettes on Perceptions and Behavior - Remote Substudy # 1
Status: COMPLETED
Conditions: Electronic Cigarette Use|Cigarette Smoking|Cigarette Use, Electronic|Vaping
Interventions: OTHER: Control Marketing Strategies|OTHER: Experimental Marketing Strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Investigating the Influence of Age and Saliva Flow on the Perception of Protein Fortified Foods and Beverages
Status: COMPLETED
Conditions: Individual Difference|Food Sensitivity|Food Preferences
Interventions: BEHAVIORAL: Solid Model|BEHAVIORAL: Liquid Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Pharmacokinetics of Single-dose Dolutegravir in HIV-seronegative Subjects With Severe Hepatic Impairment Compared to Matched Controls.
Status: WITHDRAWN
Conditions: HIV-1-infection|Hepatic Impairment
Interventions: DRUG: Dolutegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Bioequivalence Study of Two Formulations of 10-mg Empagliflozin Tablets in Healthy Thai Volunteers Under Fasting Conditions
Status: NOT_YET_RECRUITING
Conditions: Healthy Vollunteer
Interventions: DRUG: Empagliflozin 10 mg tablets|DRUG: JARDIANCE®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Personalized Hemodynamic Management in High-risk Major Abdominal Surgery
Status: RECRUITING
Conditions: Cardiac Output|Surgery|Postoperative Complications|Anesthesia
Interventions: OTHER: Personalized hemodynamic management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Containing Coronavirus Disease 19 (COVID-19) Trial
Status: COMPLETED
Conditions: SARS-CoV Infection|Interferon|Covid19
Interventions: BIOLOGICAL: Peginterferon beta-1a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Trifunctional Antibody FBTA05 and Donor Lymphocyte Infusion in B-cell Lymphoma After Allogeneic Stem Cell Transplantation
Status: WITHDRAWN
Conditions: Leukemia|Stem Cell Transplantation
Interventions: DRUG: FBTA05
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Training in a Local Community Aimed Upon Musculoskeletal Health Promotion for Postmenopausal Women
Status: COMPLETED
Conditions: Age-Related Osteoporosis
Interventions: BEHAVIORAL: multimodal training (MMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of the Glaukos Trabecular Micro-bypass Stent in Open Angle Glaucoma Subjects 1 Stent Versus 2
Status: UNKNOWN
Conditions: Open-Angle Glaucoma
Interventions: DEVICE: Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging Study of the Distribution of IL13-PE38QQR Infused Before and After Surgery in Adult Patients With Recurrent Malignant Glioma
Status: COMPLETED
Conditions: Malignant Glioma|Glioblastoma Multiforme|Anaplastic Astrocytoma|Anaplastic Oligodendroglioma|Mixed Oligoastrocytoma
Interventions: DRUG: IL13-PE38QQR|PROCEDURE: targeted fusion protein therapy|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a Non-invasive In-vitro Diagnostic Test (Peptest) Against Other Diagnostic Methods for GERD
Status: COMPLETED
Conditions: Gastro-esophageal Reflux Disease
Interventions: OTHER: in vitro diagnostic test (Peptest)|OTHER: Questionnaire|OTHER: Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multimodal Analgesic Management of Naborphine Combined With Opioid Free Anesthesia in OSA Patients Undergoing Bariatric Surgery
Status: UNKNOWN
Conditions: Analgesics，Opioid|Bariatric Surgery
Interventions: PROCEDURE: Opioid free anesthesia technology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Antinociceptive and Analgesic Effects of Milnacipran
Status: COMPLETED
Conditions: Fibromyalgia Syndrome
Interventions: DRUG: Milnacipran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dual Targeting of EGFR With Cetuximab and Afatinib to Treat Refractory wtKRAS Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Cetuximab + Afatinib|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Escalating Dose Study Of Ertugliflozin (PF-04971729, MK-8835) Under Fed and Fasted Conditons In Healthy Volunteers (MK-8835-036)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Ertugliflozin|DRUG: Placebo to Ertugliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Anti-viral T-cell Therapy by Gamma Capture
Status: ENROLLING_BY_INVITATION
Conditions: Adenovirus|Cytomegalovirus Infections|Epstein-Barr Virus Infections
Interventions: BIOLOGICAL: Specific T- Lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Angiotensin Receptors and Age Related Mitochondrial Decline in HIV Patients
Status: TERMINATED
Conditions: HIV|Aging|Sarcopenia|Angiotensin Receptor Antagonists
Interventions: DRUG: valsartan|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Compression Stockings for Treating Vasovagal Syncope Trial
Status: RECRUITING
Conditions: Syncope, Vasovagal
Interventions: DEVICE: Compression Stockings with 25-30 mm Hg pressure|DEVICE: Compression stockings with up to <=10 mm Hg pressure|BEHAVIORAL: Lifestyle modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-resorbable Membranes Versus Titanium Meshes and Resorbable Membranes
Status: COMPLETED
Conditions: Surgical Procedure, Unspecified|Soft Tissue Infections|Bone Density|Bone Loss|Dental Implant
Interventions: DEVICE: Group A - control group|DEVICE: Group B - Test group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Malaria Vaccine RTS,S/AS01E in Plasmodium Falciparum-infected and Uninfected Adults Pre-treated With Anti-malarial Therapy
Status: COMPLETED
Conditions: Plasmodium Falciparum
Interventions: BIOLOGICAL: Malaria Vaccine RTS,S/AS01E|BIOLOGICAL: Abhayrab rabies vaccine|DRUG: Dihydroartemisinin-piperaquine (DHA/Pip)|DRUG: Artemether / Lumefantrine|DRUG: Primaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Absorb IV Randomized Controlled Trial
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Artery Stenosis|Coronary Disease|Coronary Stenosis
Interventions: DEVICE: Absorb BVS|DEVICE: XIENCE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cervical Sliding Sign to Predict Outcome of Induction of Labor
Status: ACTIVE_NOT_RECRUITING
Conditions: Induction of Labor|Transvaginal Ultrasound: Cervical Sliding Sign
Interventions: DEVICE: Transvaginal ultrasound|DRUG: Misoprostol 200mcg Tab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gene Therapy for B-Cell Acute Lymphoblastic Leukemia
Status: NOT_YET_RECRUITING
Conditions: B-cell Acute Lymphoblastic Leukemia
Interventions: GENETIC: Dose Level 1, VNX-101|GENETIC: Dose Level 2, VNX-101|GENETIC: Dose Level 3, VNX-101|GENETIC: Dose Level 4, VNX-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of JMT101 Combined With Afatinib (or Osimertinib) in Patients With Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Interventions: DRUG: JMT101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medial vs. Entire Supraclavicular Lymph Node Radiation Therapy for Patients With Invasive Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Radiotherapy; Complications|Effect of Radiation Therapy
Interventions: RADIATION: Entire supraclavicular lymph node radiotherapy|RADIATION: Medial supraclavicular lymph node radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Long-Term Safety of Pirfenidone (Esbriet) in Participants With Idiopathic Pulmonary Fibrosis (IPF)
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Pirfenidone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improvement of Patients With Chronic Heart Failure Using NT-proBNP
Status: UNKNOWN
Conditions: Congestive Heart Failure
Interventions: OTHER: NT-proBNP guided care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Intensive Chemotherapy With or Without Glasdegib or Azacitidine With or Without Glasdegib In Patients With Previously Untreated Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: glasdegib|DRUG: daunorubicin + cytarabine|DRUG: azacitidine|DRUG: Placebo|DRUG: Placebo|DRUG: glasdegib|DRUG: cytarabine|PROCEDURE: HSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Manipulation of the Aorta and Cerebral Infarction
Status: UNKNOWN
Conditions: Coronary Heart Disease|Stroke|Cerebral Infarction
Interventions: PROCEDURE: OBCAB (Off Pump Coronary Artery Bypass Grafting)|PROCEDURE: CABG (coronary artery bypass grafting)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Stiffness of Lumbar Spine and Hamstrings Muscle Stretching
Status: COMPLETED
Conditions: Back Pain|Instability Lumbar Spine|Muscle Tightness
Interventions: OTHER: Lumbopelvic stiffening technique|OTHER: Lumbopelvic relaxing technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thiotepa-based Conditioning for Allogeneic Stem-cell Transplantation (SCT) in Lymphoid Malignancies
Status: UNKNOWN
Conditions: Non Hodgkin Lymphoma|Hodgkin Lymphoma|Chronic Lymphocytic Leukemia|Multiple Myeloma
Interventions: DRUG: Thiotepa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irinotecan, Cisplatin, Bevacizumab, Radiation Therapy, and Surgery in Treating Patients With Locally Advanced Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: cisplatin|DRUG: irinotecan hydrochloride|GENETIC: proteomic profiling|OTHER: diagnostic laboratory biomarker analysis|OTHER: mass spectrometry|PROCEDURE: adjuvant therapy|PROCEDURE: neoadjuvant therapy|PROCEDURE: therapeutic conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Older Veterans With Chronic Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Combat Disorders|Post-traumatic Stress Disorder
Interventions: BEHAVIORAL: Prolonged Exposure Therapy (PE)|BEHAVIORAL: Relaxation Training (RT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Linagliptin and Metformin Versus Linagliptin in Newly Diagnosed, Untreated Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: metformin|DRUG: linagliptin|DRUG: metformin placebo|DRUG: metformin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Benefit of Topical Hemostatic Powder Containing Hydrophilic Polymer With Potassium Ferrate for Hemostasis Following Nail Surgery
Status: WITHDRAWN
Conditions: Nail Diseases
Interventions: DEVICE: Hydrophilic polymer and potassium ferrate powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: EBV Specific T-Lymphocytes for Treatment of EBV-Positive Lymphoma
Status: RECRUITING
Conditions: EBV-Related Hodgkin Lymphoma|EBV-Related Lymphoproliferative Disorder|EBV Related Non-Hodgkin's Lymphoma
Interventions: BIOLOGICAL: Dose Level 1A: 2 x 10^7 cells/m2|BIOLOGICAL: Dose Level 2A: 6 x 10^7 cells/m2|BIOLOGICAL: Dose Level 2B: 6 x 10^7 cells/m2|BIOLOGICAL: Dose Level 3B: 2 x 10^8 cells/m2|BIOLOGICAL: Dose Level 3A: 2 x 10^8 cells/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Delineation of Novel Monogenic Disorders in the United Arab Emirates Population
Status: UNKNOWN
Conditions: Mendelian Disorders|Genetic Disorder|Novel Mutation|Hereditary Disorder|De Novo Mutation|Inherited Disease|Single-Gene Defects
Interventions: GENETIC: Sanger and/or Next Generation Sequencing (NGS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Oral Desmopressin in Previously Untreated Children Aged 5 to 15 Years With Primary Nocturnal Enuresis
Status: COMPLETED
Conditions: Nocturnal Enuresis
Interventions: DRUG: Primary nocturnal enuresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Effect of Delgocitinib on the Heart Rhythm of Healthy People
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Delgocitinib capsule|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Trial of Linaclotide in Patients With Chronic Idiopathic Constipation
Status: COMPLETED
Conditions: Chronic Idiopathic Constipation
Interventions: DRUG: Linaclotide|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gene Analysis in Studying Susceptibility to Wilms Tumor
Status: COMPLETED
Conditions: Recurrent Childhood Kidney Neoplasm|Stage I Kidney Wilms Tumor|Stage II Kidney Wilms Tumor|Stage III Kidney Wilms Tumor|Stage IV Kidney Wilms Tumor
Interventions: OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immediate Versus Optional Delayed Surgical Repair for Treatment of Acute ACL Injuries
Status: RECRUITING
Conditions: ACL Injury
Interventions: OTHER: Rehabilitation|PROCEDURE: Optional delayed anterior cruciate ligament reconstruction|PROCEDURE: Immediate anterior cruciate ligament reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Anecortave Acetate in Patients With a Retisert Implant
Status: COMPLETED
Conditions: Uveitis, Posterior|Glaucoma
Interventions: DRUG: anecortave acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Tezepelumab in Adults & Adolescents With Severe Uncontrolled Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: Experimental: Tezepelumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Contour 3D®/TriAd® Tricuspid Annuloplasty Ring Post-Market Clinical Trial
Status: COMPLETED
Conditions: Tricuspid Valve Regurgitation|Tricuspid Valve Insufficiency
Interventions: DEVICE: Contour 3D® implant for tricuspid valve repair|DEVICE: Tri-Ad® implant for tricuspid valve repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Transcutaneous Electrical Acupoint Stimulation on Sleep After Thoracoscopic Surgery
Status: COMPLETED
Conditions: Transcutaneous Electrical Acupoint Stimulation|Thoracoscopic Surgery|Postoperative Sleep Quality
Interventions: OTHER: Transcutaneous Electrical Acupoint Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Guided Radiofrequency Ablation of Proximal Greater Occipital Nerve in Primary Occipital Neuralgia
Status: COMPLETED
Conditions: Occipital Neuralgia
Interventions: PROCEDURE: Ultrasound-guided proximal greater occipital nerve radiofrequency ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Internet Self-Management Program With Telephone Support for Adolescents With Arthritis
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: BEHAVIORAL: Teens Taking Charge|BEHAVIORAL: Self-Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROCLAIM: CX-072-002: Study of PD-L1 Probody Therapeutic CX-072 in Combination With Other Anticancer Therapy in Adults With Solid Tumors
Status: TERMINATED
Conditions: Solid Tumor|Unresectable or Metastatic Melanoma
Interventions: DRUG: CX-072|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Camrelizumab in Combination With Cisplatin and Nab-paclitaxel in Resectable HNSCC
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Camrelizumab, nab-paclitaxel, cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Financial Navigation Study Among Young Adult Blood Cancer Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Survivorship|Cancer|Financial Stress
Interventions: BEHAVIORAL: Providing financial navigation via active navigation, ad hoc navigation or no study-based navigation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: ARTEMIS-008：HS-20093 Compared With Topotecan in Subjects With Relapsed Small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Small Cell Lung Cancer
Interventions: DRUG: HS-20093|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Multi-disciplinary Integrated Post-acute Care in Patients Admission for Heart Failure
Status: COMPLETED
Conditions: Hospitalization Rate|Mortality Rate|Functional Recovery|Left Ventricle Ejection Fraction|NT-pro BNP
Interventions: OTHER: Not intervention.Use retrospective case contrl study.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of dapaglifloziN Therapy on Myocardial Perfusion Reserve in Prediabetic Patients With Stable coronarY Artery Disease
Status: TERMINATED
Conditions: Coronary Artery Disease|Prediabetic State
Interventions: DRUG: Dapagliflozin 10mg|OTHER: Lifestyle modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of Nidufexor in Patients With Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: Nidufexor|OTHER: Placebo|DRUG: Standard of Care (SoC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tenofovir DF (Disoproxil Fumarate) in Combination With Emtricitabine in HIV-1 Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Truvada (tenofovir DF + emtricitabine)|DRUG: Emtriva (emtricitabine)|DRUG: Viread (tenofovir DF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT