pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Low Dose Naltrexone for Chronic Pain in Osteoarthritis and Inflammatory Arthritis
Status: WITHDRAWN
Conditions: Osteoarthritis|Arthritis, Rheumatoid|Arthritis, Psoriatic
Interventions: DRUG: Naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: mFOLFIRI as the Second Line Chemotherapy for Advanced Esophageal Carcinoma After Failure of 1st Line Treatment of Paclitaxel/DDP : a Phase II Single Center Prospective Clinical Trial
Status: UNKNOWN
Conditions: Advanced Esophageal Carcinoma
Interventions: DRUG: mFOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anterior Pelvic Prolapse Reconstruction With TiLOOP® PRO A Polypropylene Mesh
Status: COMPLETED
Conditions: Cystocele|Uterine Prolapse
Interventions: DEVICE: TiLOOP® PRO Plus A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Talquetamab in Combination With Daratumumab or in Combination With Daratumumab and Pomalidomide Versus Daratumumab in Combination With Pomalidomide and Dexamethasone in Participants With Multiple Myeloma That Returns After Treatment or is Resistant to Treatment
Status: RECRUITING
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: DRUG: Talquetamab|DRUG: Daratumumab|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Physical Activity and Low-Dose Ibuprofen on Cognitive Function in Cancer Patients
Status: COMPLETED
Conditions: Cancer-related Cognitive Difficulties
Interventions: DRUG: Ibuprofen|BEHAVIORAL: Home-Based Exercise|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Total Glucosides of Paeony Combined With Acitretin to Treat Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Total glucosides of paeony & Acitretin Capsules|DRUG: Acitretin Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Photodynamic Therapy With Low-level Laser on Infected Dentin in Primary Teeth: A Controlled Clinical Trial
Status: UNKNOWN
Conditions: Dental Caries
Interventions: DRUG: PapacarieMBlue and PDT|DRUG: Toluidine Blue O and PDT|DEVICE: Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AnticoaguLation ONE Year After Ablation of Atrial Fibrillation in Patients With Atrial Fibrillation (ALONE AF Study)
Status: RECRUITING
Conditions: Atrial Fibrillation Patients With Moderate or High Stroke Risk Who Had Undergone Catheter Ablation of Atrial Fibrillation
Interventions: DRUG: Anticoagulation group(Apixaban group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Pre-prosthetic Surgical Techniques for Augmentation of Mandibular Vertical Ridge Defects
Status: COMPLETED
Conditions: Alveolar Ridge Enlargement
Interventions: DEVICE: customised ceramic sheets (Group 1)|COMBINATION_PRODUCT: modified sausage technique (Group 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of Tocilizumab in Patients With Moderate to Severe Active Rheumatoid Arthritis Who Have an Inadequate Response to or Are Unable to Tolerate Biologic and Non-Biologic Disease-modifying Antirheumatic Drugs (DMARDs)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab [RoActemra/Actemra]|DRUG: tocilizumab [RoActemra/Actemra]|DRUG: Nonbiologic DMARDs of investigator's choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TRAUMED - a Clinical Trial in Acute Ankle Sprain
Status: COMPLETED
Conditions: Ankle Sprain
Interventions: DRUG: Traumeel®|DRUG: Diclofenac sodium gel 1%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Weekly Topotecan With Cisplatin in Advanced Stage or Recurrent Cervical Cancer
Status: TERMINATED
Conditions: Cervix Cancer
Interventions: DRUG: Topotecan|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Two Home Ergonomics Programmes in Post-stroke Patients
Status: COMPLETED
Conditions: Stroke|Quality of Life
Interventions: OTHER: Ergonomic adjustments|OTHER: Kinesiotherapy plus ergonomic adjustments|OTHER: Healthcare education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating UCART20x22 in B-Cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: B-cell Non-Hodgkin Lymphoma (B-NHL)
Interventions: BIOLOGICAL: UCART20x22|BIOLOGICAL: CLLS52
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbon Monoxide Migraine-inducing Effects in Patients With Migraine Without Aura.
Status: COMPLETED
Conditions: Headache, Migraine
Interventions: OTHER: Carbon monoxide|OTHER: AIR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Image Fusion of SPECT MPI and Fluoroscopy Venography to Guide LV Lead Placement for Improved CRT Response (GUIDE-CRT II)
Status: RECRUITING
Conditions: Chronic Heart Failure
Interventions: OTHER: Image fusion of SPECT MPI and fluoroscopy venography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigate Effects of a2 Milk on Breastmilk Composition and Subsequent Infant Gut Health, Crying and Sleep Patterns in Healthy, Full-term Infants
Status: RECRUITING
Conditions: Digestive System Disease|Sleepiness|Crying
Interventions: DIETARY_SUPPLEMENT: a2 Full Cream Milk|DIETARY_SUPPLEMENT: Conventional Milk (Weidendorf)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease|Cognitive Dysfunction|Dementia
Interventions: DRUG: JNJ-63733657|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of Oral AKST4290 in Participants With Moderately Severe to Severe Diabetic Retinopathy (CAPRI)
Status: TERMINATED
Conditions: Diabetic Retinopathy
Interventions: DRUG: AKST4290|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FBCx (Alpha-CD) Mechanism of Action Trial
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Alpha-cyclodextrin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Deuremidevir Hydrobromide for Suspension in Chinese Infants Hospitalized With RSV
Status: RECRUITING
Conditions: Respiratory Syncytial Virus Infection
Interventions: DRUG: Deuremidevir Hydrobromide for Suspension|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Stereotactic Body Radiotherapy as a Bridge Therapy for Hepatocellular Carcinoma Patients Enlisted for Liver Transplantation
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: Stereotactic Body Radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prevention of Recurrence of Venous Thromboembolism in Patients With a History of Venous Thromboembolism
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: YM150
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Low Level Laser Therapy and Pelvic Stabilisation Exercises on Postpartum Pelvic Girdle Pain
Status: UNKNOWN
Conditions: Pelvic Girdle Pain
Interventions: OTHER: low level laser therapy|OTHER: pelvic stabilization exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate Ocrelizumab Compared With Placebo in Patients With Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate Therapy
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Methotrexate|DRUG: Ocrelizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rivaroxaban or Aspirin for Biological Aortic Prosthesis
Status: UNKNOWN
Conditions: Aortic Stenosis|Aortic Regurgitation|Thrombosis
Interventions: DRUG: Rivaroxaban 10 MG|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Study to Investigate The Diagnostic Yield and Utility of 22g and 19g Endobronchial Ultrasound Transbronchial Needle Aspirate
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: PROCEDURE: Endobronchial ultrasound (EBUS) transbronchial needle aspirate (TBNA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sigh Ventilation on Postoperative Hypoxemia in Cardiac Surgery
Status: RECRUITING
Conditions: Hypoxemia|Postoperative Complications|Cardiac Disease|Acute Lung Injury
Interventions: PROCEDURE: Sigh ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can Blood Flow Restriction Therapy Improve Strength and Cross-Sectional Area for Shoulder External Rotators Better Than Exercise Alone?
Status: UNKNOWN
Conditions: Can Blood Flow Restriction Therapy Augments Strength Gains in the Rotator Cuff|Muscle Weakness
Interventions: OTHER: Blood Flow Restriction Group (exercise with blood flow restriction using a Delfi unit)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a New Inactivated Polio Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: DRUG: IPV|DRUG: Sabin-IPV|DRUG: Adjuvanted Sabin-IPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Botulinum Toxin Alone Versus Combined Botulinum Toxin and Topical Diltiazem in Chronic Anal Fissure
Status: COMPLETED
Conditions: Anal Fissure Chronic
Interventions: DRUG: Botulinum Toxin Type A Injection [Botox]|DRUG: Botulinum Toxin Type A Injection [Botox] + Diltiazem Hydrochloride 20 Mg/G Rectal Gel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Study of Neo-adjuvant and Adjuvant Pembrolizumab With and Without Targeted Blood Brain Barrier Opening Using Exablate MRI-guided Focused Ultrasound (Exablate MRgFUS) for Recurrent Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: Recurrent Glioblastoma
Interventions: DRUG: Pembrolizumab|DEVICE: Exablate MRgFUS + neoadjuvant pembolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing a New Jaw Support Device During Third Molar Extractions
Status: COMPLETED
Conditions: Impacted Third Molar Tooth|Temporomandibular Disorder
Interventions: DEVICE: The Restful Jaw Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Transversalis Fascia Plane Block in Pediatric Inguinal Hernia Repair
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: DRUG: Bupivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Treatment of Taurine in Children With Autism
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DIETARY_SUPPLEMENT: Taurine+corn starch+white sugar|DIETARY_SUPPLEMENT: Corn starch+white sugar|BEHAVIORAL: Behavioral rehabilitation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy of Metformin in the Treatment of Acanthosis Nigricans in Children With Obesity
Status: UNKNOWN
Conditions: Acanthosis Nigricans
Interventions: DRUG: Metformin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chatbot-based Positive Psychology Intervention in Caregivers of Children With Autism Spectrum Disorder
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Chatbot-based positive psychology intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Randomized Phase I Study of Trimetrexate Glucuronate (TMTX) With Leucovorin (LCV) Protection Plus Dapsone Versus Trimethoprim / Sulfamethoxazole (TMP/SMX) for Treatment of Moderately Severe Episodes of Pneumocystis Carinii Pneumonia
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Trimetrexate glucuronate|DRUG: Trimethoprim|DRUG: Sulfamethoxazole|DRUG: Dapsone|DRUG: Leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Hymecromone Tablets for the Treatment of Patients With COVID-19.
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Hymecromone tablets|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intensive Dietary Education on Nutritional Status After Gastrectomy(SING)
Status: RECRUITING
Conditions: Gastric Cancer|Gastrectomy
Interventions: OTHER: Dietary education(nutritional counselling)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 1a Study to Evaluate Immunogenicity of ASV®
Status: COMPLETED
Conditions: Solid Tumor, Adult
Interventions: BIOLOGICAL: ASV® AGEN2017 + QS-21 Stimulon® adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab With or Without Ipilimumab in Treating Patients With Gastrointestinal Stromal Tumor That Is Metastatic or Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumor
Interventions: BIOLOGICAL: Ipilimumab|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Catheter Ablation of Haemodynamically Not-tolerated Electrical Storm in Structural Heart Disease
Status: NOT_YET_RECRUITING
Conditions: Ventricular Tachycardia
Interventions: PROCEDURE: Catheter ablation|PROCEDURE: Stepped-care strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Vitamin D Supplementation in Adolescents With Asthma, Obesity and Vitamin D Deficiency.
Status: RECRUITING
Conditions: Non-allergic Asthma|Obesity|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D₃ (25-hydroxy vitamin D)|DIETARY_SUPPLEMENT: Vitamin D₃ (25-hydroxy vitamin D)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: CEUS Evaluation of Hypoxic Ischemic Injury
Status: COMPLETED
Conditions: Hypoxic-Ischemic Encephalopathy|Brain Ischemia Hypoxia
Interventions: DRUG: Sulfur hexafluoride lipid-type A microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nitrate INFORMER Meat Study
Status: COMPLETED
Conditions: Health Risk Behaviors
Interventions: DIETARY_SUPPLEMENT: Meat with added nitrate|DIETARY_SUPPLEMENT: Meat without added nitrate|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess Adverse Events and Change in Disease Condition of Mesalamine Capsules in Children Aged 5 to 17 Years With Ulcerative Colitis
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis (UC)
Interventions: DRUG: Mesalamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine if AZD0284 is Effective and Safe in Treating Plaque Psoriasis
Status: TERMINATED
Conditions: Plaque Psoriasis Vulgaris
Interventions: DRUG: AZD0284 oral solution 2.5 mg/mL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mobile EMA-based Peer Counselling for Youth Smokers
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: EMA assessment|BEHAVIORAL: EMA-based cessation counselling|BEHAVIORAL: Usual peer counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of 2 Fixed Dose Combinations of Empagliflozin/Metformin Compared With Single Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Empagliflozin/Metformin XR, FDC|DRUG: Empagliflozin/Metformin XR FDC|DRUG: 25 mg Empagliflozin/1000 mg Metformin XR, FDC|DRUG: 1 tablet Empagliflozin/2 tablets Metformin XR|DRUG: 1 tablet Empagliflozin/3 tablets Metformin XR|DRUG: 1 tablet Empagliflozin/2 tablets Metformin XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Depressive Relapse in Pregnant Women With Recurrent Depression
Status: COMPLETED
Conditions: Depression|Pregnancy Related|Antenatal Depression
Interventions: BEHAVIORAL: Digital Delivery of Mindfulness-Based Cognitive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Safety, Tolerability, and Efficacy of Secukinumab in Subjects With Moderate to Severe Nail Psoriasis
Status: COMPLETED
Conditions: Moderate to Severe Nail Psoriasis
Interventions: BIOLOGICAL: Secukinumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation for Treating Women With Chronic Widespread Pain
Status: COMPLETED
Conditions: Fibromyalgia|Chronic Pain|Depression
Interventions: DEVICE: rTMS|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short Term Physiological Effects of Nasal High Flow Oxygen on Respiratory Mechanics
Status: COMPLETED
Conditions: COPD|Chronic Hypercapnic Respiratory Failure
Interventions: DEVICE: HOF|DEVICE: noninvasive mechanical ventilation (NIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Quadratus Lumborum Block Versus Rectus Sheath Block
Status: RECRUITING
Conditions: Quadratus Lumborum Block and Rectus Sheath Block
Interventions: PROCEDURE: Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Effectiveness Evaluation of COBRA PzF Coronary Stent System: A Post Marketing Observational Registry
Status: COMPLETED
Conditions: Stable Angina|Unstable Angina|ACS - Acute Coronary Syndrome|STEMI|NSTEMI - Non-ST Segment Elevation MI|Myocardial Infarction
Interventions: DEVICE: COBRA PzF Coronary Stent System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Very Low Carbohydrate Diet Effects to GPS, Serum Lactate and TNF Alpha on Colorectal Cancer
Status: UNKNOWN
Conditions: Diet Modification|Colorectal Adenocarcinoma|Systemic Inflammation|TNF Alpha|Lactate
Interventions: OTHER: Very Low Carbohydrate Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Paclitaxel and Carboplatin Before Radiation Therapy With Paclitaxel in Treating HPV-Positive Patients With Stage III-IV Oropharynx, Hypopharynx, or Larynx Cancer
Status: COMPLETED
Conditions: Human Papilloma Virus Infection|Stage III Squamous Cell Carcinoma of the Hypopharynx|Stage III Squamous Cell Carcinoma of the Larynx|Stage III Squamous Cell Carcinoma of the Oropharynx|Stage III Verrucous Carcinoma of the Larynx|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Verrucous Carcinoma of the Larynx|Stage IVA Squamous Cell Carcinoma of the Larynx|Stage IVA Squamous Cell Carcinoma of the Oropharynx|Stage IVA Verrucous Carcinoma of the Larynx|Stage IVB Squamous Cell Carcinoma of the Larynx|Stage IVB Squamous Cell Carcinoma of the Oropharynx|Stage IVB Verrucous Carcinoma of the Larynx|Stage IVC Squamous Cell Carcinoma of the Larynx|Stage IVC Squamous Cell Carcinoma of the Oropharynx|Stage IVC Verrucous Carcinoma of the Larynx
Interventions: DRUG: paclitaxel|DRUG: carboplatin|RADIATION: intensity-modulated radiation therapy|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dosage Vitamin D and Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis|Osteopenia
Interventions: DRUG: cholecalciferol (Vitamin D3)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Exacerbation of COPD and Nebulized Magnesium Sulphate
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease Exacerbation|Magnesium Sulfate
Interventions: DRUG: Nebulized Magnesium Sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Proprioceptive Neuromuscular Facilitation in Older Women With Gonarthrosis
Status: COMPLETED
Conditions: Osteoarthritis Knee
Interventions: OTHER: Proprioceptive neuromuscular facilitation (PNF)|OTHER: Resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Low-Dose Interleukin-2 by Subcutaneous Injection in Combination With Antiretroviral Therapy Versus Antiretroviral Therapy Alone in Patients With HIV-1 Infection and at Least 3 Months Stable Antiretroviral Therapy
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Sitosterolemia Extension Study (0653-004)(COMPLETED)
Status: COMPLETED
Conditions: Lipid Metabolism, Inborn Errors|Heart Disease
Interventions: DRUG: MK0653, ezetimibe|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study to Learn More About the Safety of Darolutamide in Men With Prostate Cancer in Korea
Status: NOT_YET_RECRUITING
Conditions: Non-metastatic Castration-resistant Prostate Cancer|Metastatic Hormone-sensitive Prostate Cancer
Interventions: DRUG: Darolutamide (Nubeqa, BAY1841788)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Sustained Virological Response in Relation to IL28-b Expression in Treatment-Naïve Patients With Chronic Hepatitis C Genotype 1 on Combination Treatment With Pegasys (Peginterferon Alfa-2a) and Copegus (Ribavirin)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: peginterferon alfa-2a|DRUG: ribavirin [Copegus]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preparing and Timing of the Endometrium in Modified Natural Cycle Frozen-thawed Embryo Transfers
Status: ACTIVE_NOT_RECRUITING
Conditions: Infertility
Interventions: DRUG: Lutinus + transfer day 6|DRUG: Lutinus + transfer day 7|DRUG: No Lutinus + transfer day 6|DRUG: No Lutinus + transfer day 7
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Belzutifan (MK-6482) in Participants With Advanced Clear Cell Renal Cell Carcinoma (MK-6482-018)
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Belzutifan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Palbociclib and Trastuzumab With Endocrine Therapy in HER2-positive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Palbociclib|DRUG: Trastuzumab|DRUG: Endocrine therapy|DRUG: Chemotherapy|DRUG: Antibody-Drug Conjugates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Complications Associated With Central Venous Access in the NSICU: PICC vs CVC
Status: COMPLETED
Conditions: PICC|Central Venous Catheter|Central Line|Neuro ICU|Neuroscience ICU|CVC
Interventions: DEVICE: peripherally inserted central catheter|DEVICE: centrally inserted central catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Netherlands 10 mL Bronchoscopic Lung Volume Reduction (BLVR) Phase 1/2 Emphysema Study - Initial Formulation
Status: TERMINATED
Conditions: Pulmonary Emphysema
Interventions: BIOLOGICAL: BLVR Hydrogel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis (Integument-PED)
Status: COMPLETED
Conditions: Atopic Dermatitis Eczema
Interventions: DRUG: ARQ-151 Active|DRUG: ARQ-151 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of BEA 2180 BR in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BEA 2180 BR solution for infusion|DRUG: Placebo|DRUG: BEA 2180 BR solution for inhalation|DEVICE: Respimat®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cocoa Products on Cardiovascular Disease Risk Factors
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Cocoa product type 1|DIETARY_SUPPLEMENT: Cocoa product type 2|DIETARY_SUPPLEMENT: Cocoa product type 3|DIETARY_SUPPLEMENT: Cocoa product type 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Canadian EdoxAban(Lixiana®) Registry in Patients With ATrial Fibrillation/Flutter With Confirmed ValvUlar HeaRt DiseasE
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation and Flutter|Valvular Heart Disease
Interventions: DRUG: Edoxaban Pill
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Paracetamol and Ketorolac on RANK-L Levels in Patients Starting Orthodontic Treatment
Status: UNKNOWN
Conditions: Malocclusion|Pain, Acute
Interventions: DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Protecting Autologous Free Flaps From Ischemia/Reperfusion Damage With Cold Storage.
Status: NOT_YET_RECRUITING
Conditions: Ischemia Reperfusion Injury
Interventions: DEVICE: University of Wisconsin solution + cold storage|OTHER: Unperfused free flap under warm ischemia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Antimalarial Drugs Used for the Treatment of Uncomplicated Malaria, Plasmodium Falciparum, at the Agadez, Gaya and Tessaoua Sentinel Sites
Status: COMPLETED
Conditions: MALARIA
Interventions: DRUG: Artemether-lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing Adverse Event and How Oral ABBV-453 Moves Through the Body in Adult Participants With Relapsed or Refractory (R/R) Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Obinutuzumab|DRUG: ABBV-453
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of 10 kHz SCS Combined With CMM to CMM Alone in the Treatment of Neuropathic Limb Pain
Status: UNKNOWN
Conditions: Painful Diabetic Neuropathy
Interventions: DEVICE: Senza HF10 Therapy|OTHER: CMM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Oral Acetazolamide in Decongestion in Patients With Heart Failure
Status: NOT_YET_RECRUITING
Conditions: Heart Failure
Interventions: OTHER: Acetazolamide|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetic Characteristics Evaluation of DA-302168S Tablets
Status: RECRUITING
Conditions: Overweight and Obesity
Interventions: DRUG: DA-302168S|DRUG: Placebo of DA-302168S|DRUG: DA-302168S|DRUG: Placebo of DA-302168S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Erlotinib Study in Advanced Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasms
Interventions: DRUG: bevacizumab|DRUG: erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protective Effects of Delayed Cord Clamping in Very Low Birth Weight (VLBW) Infants
Status: COMPLETED
Conditions: Intraventricular Hemorrhage|Sepsis
Interventions: PROCEDURE: delayed umbilical cord clamping|OTHER: Immediate cord clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Effects of the Education Given to Nursing Students by Gamification Method and Flipped Learning Method on the Level of Participation, Attitude, Interest and Motivation
Status: COMPLETED
Conditions: Educational Problems
Interventions: BEHAVIORAL: Gamification method group|BEHAVIORAL: Flipped learning group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Natural Killer Cell (CYNK-001) IV Infusion or IT Administration in Adults With Recurrent GBM
Status: TERMINATED
Conditions: Astrocytoma, Grade IV|Giant Cell Glioblastoma|Glioblastoma Multiforme|Cyclophosphamide|Immunosuppressive Agents|Immunologic Factors|Physiological Effects of Drugs|Molecular Mechanisms of Pharmacological Action|Antiviral Agents|Anti-infective Agents|Analgesics, Non-narcotic|Analgesics|Sensory System Agents|Peripheral Nervous System Agents
Interventions: BIOLOGICAL: CYNK001-IV|BIOLOGICAL: CYNK001-IT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ranibizumab Versus Aflibercept for CRVO in Young Patients.
Status: UNKNOWN
Conditions: Non-Ischemic Central Retinal Vein Occlusion With Macular Edema
Interventions: PROCEDURE: intravitreal injection of Ranibizumab|PROCEDURE: intravitreal injection of Aflipercept|DRUG: Ranibizumab|DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Total Glucosides Paeony Capsules in Maintaining Clinical Remission in Patients With Ankylosing Spondylitis Which Achieve Clinical Remission After Anti-TNF Therapy
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Total Glucosides Paeony Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate Efficacy and Safety of TransCon CNP Compared With Placebo in Children With Achondroplasia
Status: ACTIVE_NOT_RECRUITING
Conditions: Achondroplasia
Interventions: DRUG: TransCon CNP|DRUG: Placebo for TransCon CNP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Beeswax-containing Barrier on the Prevention of Nipple Crack
Status: COMPLETED
Conditions: Breastfeeding|Cracked Nipple in Puerperium
Interventions: DEVICE: Beeswax containing barrier|BIOLOGICAL: Breast milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 2 Study of ABT-869 in Advanced Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: ABT-869
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amantadine and Functional Improvement Following ABI Measured by MRI Tractography; A Pilot Study
Status: UNKNOWN
Conditions: Acquired Brain Injury|Coma|Persistent Vegetative State|Minimally Conscious State|Traumatic Brain Injury
Interventions: DRUG: Amantadine|PROCEDURE: MRI Tractography Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Transcranial Direct Current Stimulation on Balance of Children With Balance Deficit
Status: UNKNOWN
Conditions: Postural Balance
Interventions: DEVICE: Transcranial direct current stimulation (tDCS)|OTHER: Balance exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ascorbic Acid and Thiamine Effect in Septic Shock
Status: COMPLETED
Conditions: Septic Shock|Sepsis
Interventions: DRUG: Combination therapy of vitamin C and thiamine|DRUG: Normal saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The FVC/DLCO Ratio is a Useful Predictor of Pulmonary Hypertension in Patients With Interstitial Lung Disease
Status: COMPLETED
Conditions: Interstitial Lung Disease|Pulmonary Hypertension
Interventions: DIAGNOSTIC_TEST: Pulmonary function test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dexamethasone Versus Nalbuphine as Adjuvants in Brachial Plexus Block
Status: COMPLETED
Conditions: Anesthesia
Interventions: PROCEDURE: Ultrasound (US) guided supraclavicular brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Learning for Fluorescein Angiography and Optical Coherence Tomography Macular Thickness Map Image Translation
Status: COMPLETED
Conditions: Eye Diseases|Diabetic Retinopathy
Interventions: DIAGNOSTIC_TEST: Fluorescein Angiography|DIAGNOSTIC_TEST: Optical coherence tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioequivalence Study of Torrent Pharmaceuticals's Ltd's Nebivolol 20 mg Tablet
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Torrent's Nebivolol Tablets|DRUG: Forest Pharmaceuticals Inc's Bystolic Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ghnnam Excision Technique for Pilonidal Sinus
Status: COMPLETED
Conditions: Pilonidal Sinus|Surgical Wound|Dressing by Cyanoacrylate
Interventions: PROCEDURE: cyanoacrylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of TCI378 and TCI507 Probiotics on Weight-lowering Efficacy in Adults
Status: UNKNOWN
Conditions: Weight Reduction
Interventions: DRUG: Placebo|DRUG: TCI378|DRUG: TCI507
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: 18F-MFBG PET/CT in the Evaluation of Neural Crest Tumor
Status: RECRUITING
Conditions: Neuroendocrine Tumor|Neuroblastoma|Pheochromocytoma|Paraganglioma
Interventions: DRUG: 18F-MFBG|DRUG: 68Ga-Dotatate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetics of Levobupivacaine After Cesarean Section
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Levobupivacaine|PROCEDURE: Spinal anesthesia|PROCEDURE: Peripheral vein canulation|PROCEDURE: Ultrasonography|DEVICE: Holter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Durvalumab and Tremelimumab in Treating Patients With Muscle-Invasive, High-Risk Urothelial Cancer That Cannot Be Treated With Cisplatin-Based Therapy Before Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Hydronephrosis|Infiltrating Bladder Urothelial Carcinoma Sarcomatoid Variant|Infiltrating Bladder Urothelial Carcinoma, Micropapillary Variant|Infiltrating Bladder Urothelial Carcinoma, Plasmacytoid Variant|Infiltrating Renal Pelvis Urothelial Carcinoma, Sarcomatoid Variant|Renal Pelvis Urothelial Carcinoma|Stage II Bladder Urothelial Carcinoma AJCC v6 and v7|Stage II Renal Pelvis Cancer AJCC v7|Stage II Ureter Cancer AJCC v7|Stage II Urethral Cancer AJCC v7|Stage III Bladder Urothelial Carcinoma AJCC v6 and v7|Stage III Renal Pelvis Cancer AJCC v7|Stage III Ureter Cancer AJCC v7|Stage III Urethral Cancer AJCC v7|Stage IV Renal Pelvis Cancer AJCC v7|Stage IV Ureter Cancer AJCC v7|Stage IV Urethral Cancer AJCC v7|Ureter Urothelial Carcinoma|Urethral Urothelial Carcinoma
Interventions: BIOLOGICAL: Durvalumab|PROCEDURE: Therapeutic Conventional Surgery|BIOLOGICAL: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Response to RSD1235 Compared to Placebo in Subjects With Atrial Arrhythmia After Heart Surgery
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DRUG: RSD1235
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Tedizolid Phosphate (TR-701 FA, MK-1986) vs Linezolid for the Treatment of Nosocomial Pneumonia (MK-1986-002)
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Tedizolid phosphate|DRUG: Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safinamide in Levodopa Induced Dyskinesia in Parkinson's Disease Subjects
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Placebo|DRUG: Safinamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy Study for the Symptomatic Treatment of Perennial Allergic Rhinitis With a 1 Year Safety Extension
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: Bilastine|DRUG: Cetirizine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Once Daily Targeted Intravenous (IV) Busulfex as Part of Reduced-toxicity Conditioning for Patients With Refractory Lymphomas Undergoing Allogeneic Transplantation
Status: COMPLETED
Conditions: Hodgkin's Lymphoma|Non-Hodgkin's Lymphoma
Interventions: DRUG: Busulfan|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Goal Directed Therapy (GDT) in Cytoreductive Surgery (CRS) and Hyperthermic Intra Peritoneal Chemotherapy (Hipec)
Status: COMPLETED
Conditions: Primary Peritoneal Neoplasm|Secondary Peritoneal Neoplasm
Interventions: DRUG: Goal Directed Intravenous Restrictive Fluid Therapy|DRUG: Conventional Intravenous Fluid therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Bone Graft Placement at Implant Installation on Buccal Plate Stability
Status: WITHDRAWN
Conditions: Peri-implant Alveolar Bone Thickness
Interventions: BIOLOGICAL: DFDBA + Bio-Gide Membrane|OTHER: Non-FDBA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Financial Incentives, Randomization With Stepped Treatment Trial
Status: COMPLETED
Conditions: Unhealthy Alcohol Use
Interventions: BEHAVIORAL: Contingency Management Counseling|BEHAVIORAL: Addiction Physician Management|BEHAVIORAL: Motivational Enhancement Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postprandial Response of Fresh-squeezed and Processed Orange Juice of Lean and Obese Subjects
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Orange juice|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: AB-101 in Combination With B-Cell Depleting mAb in Patients Who Failed Treatment for Class III or IV Lupus Nephritis or Other Forms of Refractory Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Lupus Nephritis - WHO Class III|Lupus Nephritis - WHO Class IV|Refractory Systemic Lupus Erythematosus
Interventions: DRUG: AB-101|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Rituximab|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of G-CSF, Bortezomib, Cyclophosphamide and Dexamethasone in Patients With Multiple Myeloma
Status: UNKNOWN
Conditions: Myeloma|Bortezomib|Cyclophosphamide|Dexamethasone|Granulocyte Colony-Stimulating Factor
Interventions: DRUG: G-CSF|DRUG: Bortezomib|DRUG: Cyclophosphamide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT