pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Carboplatin, Paclitaxel, Bevacizumab, and Veliparib in Treating Patients With Newly Diagnosed Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Carcinoma|Fallopian Tube Carcinosarcoma|Fallopian Tube Clear Cell Adenocarcinoma|Fallopian Tube Endometrioid Adenocarcinoma|Fallopian Tube Mucinous Adenocarcinoma|Fallopian Tube Serous Neoplasm|Fallopian Tube Transitional Cell Carcinoma|Fallopian Tube Undifferentiated Carcinoma|Ovarian Brenner Tumor|Ovarian Carcinoma|Ovarian Carcinosarcoma|Ovarian Clear Cell Adenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mucinous Adenocarcinoma|Ovarian Seromucinous Tumor|Ovarian Serous Adenocarcinoma|Ovarian Transitional Cell Carcinoma|Ovarian Undifferentiated Carcinoma|Primary Peritoneal Carcinoma|Primary Peritoneal Serous Adenocarcinoma|Stage IIA Fallopian Tube Cancer AJCC v6 and v7|Stage IIA Ovarian Cancer AJCC V6 and v7|Stage IIB Fallopian Tube Cancer AJCC v6 and v7|Stage IIB Ovarian Cancer AJCC v6 and v7|Stage IIC Fallopian Tube Cancer AJCC v6 and v7|Stage IIC Ovarian Cancer AJCC v6 and v7|Stage IIIA Fallopian Tube Cancer AJCC v7|Stage IIIA Ovarian Cancer AJCC v6 and v7|Stage IIIA Primary Peritoneal Cancer AJCC v7|Stage IIIB Fallopian Tube Cancer AJCC v7|Stage IIIB Ovarian Cancer AJCC v6 and v7|Stage IIIB Primary Peritoneal Cancer AJCC v7|Stage IIIC Fallopian Tube Cancer AJCC v7|Stage IIIC Ovarian Cancer AJCC v6 and v7|Stage IIIC Primary Peritoneal Cancer AJCC v7|Stage IV Fallopian Tube Cancer AJCC v6 and v7|Stage IV Ovarian Cancer AJCC v6 and v7|Stage IV Primary Peritoneal Cancer AJCC v7
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Carboplatin|DRUG: Cisplatin|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|DRUG: Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Thoracic Paravertebral Blocks in Patients Undergoing Reduction Mammoplasty
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Thoracic paravertebral blocks (TPVBs)|DRUG: IV metamizole sodium, paracetamol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fulvestrant and EVerolimus Plus EXemestane in Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Metastatic Breast Cancer|Breast Cancer|Hormone Receptor Positive Tumor|Human Epidermal Growth Factor 2 Negative Carcinoma of Breast|Locally Advanced Malignant Neoplasm
Interventions: DRUG: Everolimus|DRUG: Exemestane|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Video-Assisted Sudden Infant Death Syndrome Prevention Training Program and Counseling Practice on Mothers' Knowledge Level and Self-efficacy: Randomized Controlled Study
Status: NOT_YET_RECRUITING
Conditions: Sudden Infant Death
Interventions: OTHER: VASIDS-TP and Counseling Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Perioperative Systemic Therapy for Isolated Resectable Colorectal Peritoneal Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Neoplasm|Colorectal Cancer|Colorectal Neoplasms Malignant|Colorectal Carcinoma|Colorectal Adenocarcinoma|Peritoneal Neoplasms|Peritoneal Carcinomatosis|Peritoneal Cancer|Peritoneal Metastases|Peritoneal Neoplasm Malignant Secondary Carcinomatosis|Peritoneal Neoplasm Malignant Secondary
Interventions: OTHER: Perioperative systemic therapy|COMBINATION_PRODUCT: Perioperative CAPOX-bevacizumab|COMBINATION_PRODUCT: Perioperative FOLFOX-bevacizumab|COMBINATION_PRODUCT: Perioperative FOLFIRI-bevacizumab|PROCEDURE: CRS-HIPEC, experimental arm|PROCEDURE: CRS-HIPEC, control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DSS: Diabetes Surgery Study - Intensive Medical Management of Type 2 Diabetes, With and Without Gastric Bypass Surgery
Status: COMPLETED
Conditions: Type 2 Diabetes|Cardiovascular Disease
Interventions: OTHER: intensive medical management|OTHER: RYGB & IMM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Adjuvanted SCB-2020S Vaccines in Adults
Status: WITHDRAWN
Conditions: COVID-19
Interventions: BIOLOGICAL: candidate vaccine, SCB-2020S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Gemcitabine, Carboplatin, and Sorafenib in Chemotherapy-naive Patients With Advanced/Metastatic Bladder Carcinoma
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: Gemcitabine|DRUG: Carboplatin|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recombinant New Coronavirus Vaccine (CHO Cells) to Prevent SARS-CoV-2 Phase I Clinical Trial (≥60 Years Old)
Status: UNKNOWN
Conditions: Coronavirus
Interventions: BIOLOGICAL: Biological/Vaccine: Recombinant new coronavirus vaccine (CHO cell) low-dose group|BIOLOGICAL: Biological/Vaccine: Recombinant new coronavirus vaccine (CHO cells) high-dose group|BIOLOGICAL: Biological/Vaccine: Recombinant new coronavirus vaccine (CHO cells) placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Electronic Health Record Sharing System (eHRSS) Encounter Notification Service Pilot Project
Status: UNKNOWN
Conditions: Home-dwelling Elderly|Health Care Recipient
Interventions: BEHAVIORAL: Encounter notification service
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: MEDI4736 Or MEDI4736 + Tremelimumab In Surgically Resectable Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Mesothelioma
Interventions: DRUG: MEDI4736|DRUG: Tremelimumab|OTHER: no other name
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Advancing Access to Diagnostic Innovation Essential for UHC and AMR Prevention
Status: COMPLETED
Conditions: Acute Febrile Illness
Interventions: OTHER: diagnostic algorithm+Point of care rapid diagnostic tests+ Behavior change ( assessed together as a single package of interventions)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Case Review of the Penumbra and Indigo Systems for Mechanical Thrombectomy in the Periphery
Status: COMPLETED
Conditions: Peripheral Arterial Occlusion or Emboli
Interventions: DEVICE: Mechanical Thrombectomy by the Indigo System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Peer Co-led Educational Programme for Parents of Children With ADHD
Status: WITHDRAWN
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: BEHAVIORAL: Peer co-led educational group|BEHAVIORAL: Comparator treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sirolimus for Autoimmune Disease of Blood Cells
Status: COMPLETED
Conditions: Autoimmune Pancytopenia|Autoimmune Lymphoproliferative Syndrome (ALPS)|Evans Syndrome|Idiopathic Thrombocytopenic Purpura|Anemia, Hemolytic, Autoimmune|Autoimmune Neutropenia|Lupus Erythematosus, Systemic|Inflammatory Bowel Disease|Rheumatoid Arthritis
Interventions: DRUG: sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Value of Self Bone Marrow Transplants Following Chemotherapy in Scleroderma Patients
Status: TERMINATED
Conditions: Scleroderma|Systemic Sclerosis
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Thymoglobulin|PROCEDURE: Leukapheresis|PROCEDURE: Self bone marrow transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of SHR-A2102 With Adebrelimab With or Without Other Antitumor Therapy in Advanced or Metastatic Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Advanced or Metastatic Non-small Cell Lung Cancer
Interventions: DRUG: SHR-A2102；Adebrelimab；Cisplatin/ Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cut Down on Carbohydrate Usage in the Diet of Type 2 Diabetes - Mechanisms of Effective Therapy of Diabetes by Selective Choice of Macronutrients - The Phenotype Study
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: OTHER: Low carbohydrate meals|OTHER: Standard carbohydrate meals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Safety of Electrical Spinal Cord Stimulation in Parkinson's Patients Presenting With Painful Camptocormia
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Electrical spinal cord stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study Of PF-06835375 In Subjects With Seropositive Systemic Lupus Erythematosus Or Rheumatoid Arthritis
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus|Rheumatoid Arthritis
Interventions: DRUG: PF-06835375|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Potential Benefit of the Addition of BYL719 to Paclitaxel in the Treatment of Breast Cancer and Head-and-neck Cancer
Status: COMPLETED
Conditions: Neoplasms, Breast Neoplasms, Head and Neck Neoplasms
Interventions: DRUG: BYL719|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib (E7080/MK-7902) in Combination With Pembrolizumab (MK-3475) vs. Standard Chemotherapy and Lenvatinib Monotherapy in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed After Platinum Therapy and Immunotherapy (MK-7902-009/E7080-G000-228/LEAP-009)
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: Lenvatinib|BIOLOGICAL: Pembrolizumab|DRUG: Docetaxel|DRUG: Capecitabine|DRUG: Paclitaxel|DRUG: Cetuximab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PANDIA IRIS: Patients With Diabetes and Kidney Failure, an Interdisciplinary Medication Adherence Support Program
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Renal Insufficiency, Chronic
Interventions: OTHER: Inteprofessional medication adherence support program (IMAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of a Manual Therapy Protocol on Women With Pelvic Pain Due to Endometriosis
Status: COMPLETED
Conditions: Endometriosis|Pelvic Pain
Interventions: OTHER: Manual therapy|OTHER: Placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Two Different Antibiotics Versus One Antibiotic for Pediatric Perforated Appendicitis
Status: COMPLETED
Conditions: Perforated Appendicitis|Postoperative Infection
Interventions: DRUG: Piperacillin, Tazobactam Drug Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lymph Node Radiation Therapy in Patients With Stage I, Stage II, or Stage III Breast Cancer That Has Been Surgically Removed
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: PROCEDURE: adjuvant therapy|RADIATION: low-LET electron therapy|RADIATION: low-LET photon therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety and Activity Study of HER2-Targeted Dual Switch CAR-T Cells (BPX-603) in Subjects With HER2-Positive Solid Tumors
Status: SUSPENDED
Conditions: HER-2 Gene Amplification|HER2-positive Gastric Cancer|HER2-positive Breast Cancer|HER-2 Protein Overexpression|Solid Tumor, Adult
Interventions: BIOLOGICAL: chimeric antigen receptor (CAR) T cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Stimulation and Enhancing Cognition in Older Adults
Status: COMPLETED
Conditions: Cognitive Impairment, Mild|Depressive Symptoms|Anxiety
Interventions: DEVICE: Active Transcranial Direct Current Stimulation (tDCS)|DEVICE: Sham Transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DePTH: De-emphasize PTH
Status: RECRUITING
Conditions: Kidney Failure, Chronic|Chronic Kidney Disease-Mineral and Bone Disorder
Interventions: DRUG: Oral calcitriol with cinacalcet rescue|DRUG: IV activated vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Studies With 1,25-Dihydroxycholecalciferol
Status: TERMINATED
Conditions: Hypocalcemia|Rickets
Interventions: DRUG: 1,25-Dihydroxycholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pitolisant (BF2.649) in the Treatment of Excessive Daytime Sleepiness in Patients With Obstructive Sleep Apnoea Syndrome, Treated or Not by Nasal Continuous Positive Airway Pressure, But Still Complaining of Excessive Daytime Sleepiness
Status: WITHDRAWN
Conditions: Excessive Daytime Sleepiness|Obstructive Sleep Apnea
Interventions: DRUG: Pitolisant (BF2.649)|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Perineural Clonidine as an Adjuvant With Ropivacaine for Popliteal Nerve Block in Patients Undergoing Foot and Ankle Surgery
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Clonidine|DRUG: ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Trial Comparing ZD6474 With Erlotinib in NSCLC After Failure of at Least One Prior Chemotherapy
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Vandetanib|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Measuring Brain Amyloid Plaque Load in Older Adults Using BAY 94-9172
Status: COMPLETED
Conditions: Late Onset Alzheimer Disease
Interventions: DRUG: BAY 94-9172 (Florbetaben)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BI-1607 in Combination With Trastuzumab in Subjects With HER2-positive Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2-positive Breast Cancer|HER2-positive Gastric Cancer|HER2-positive Metastatic Breast Cancer|Metastatic Gastroesophageal Junction Adenocarcinoma|Metastatic Gastric Adenocarcinoma
Interventions: DRUG: BI-1607|DRUG: BI-1607|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Gender-Affirming Treatments on Pulmonary Function in Transgender and Gender Diverse Patients
Status: RECRUITING
Conditions: Hormonal Gender-Affirming Therapy
Interventions: DIAGNOSTIC_TEST: Spirometry|DIAGNOSTIC_TEST: Plethysmography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: 2-Part Multiple Ascending Dose Study for Safety and Pharmacokinetics in Healthy and Elderly Subjects
Status: COMPLETED
Conditions: CNS
Interventions: DRUG: E2006|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: New Lung Ventilation Strategies Guided by Transpulmonary Pressure in VV-ECMO for Severe ARDS
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Adult
Interventions: DEVICE: New lung ventilation strategy|DEVICE: Conventional ventilation strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Simplified Model of Linkage and Retention to Care, Using a Mobile Unit and a Same-day Test and Treat Approach Among Excluded Population. (SIMPLIFIED)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Bictegravir/Emtricitabine/Tenofovir Alafenamide 50 MG-200 MG-25 MG Oral Tablet [BIKTARVY]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Study on the Safety and Tolerability of Macitentan in Combination With Dose-dense Temozolomide in Patients With Recurrent Glioblastoma
Status: TERMINATED
Conditions: Glioblastoma
Interventions: DRUG: Phase 1 Dose Escalation|DRUG: Phase 1b|DRUG: Ancillary Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beating Lung Cancer in Ohio Protocol in Improving Survival in Patients With Stage IV Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Cigarette Smoker|Current Smoker|Lung Adenocarcinoma|Squamous Cell Lung Carcinoma|Stage IV Non-Small Cell Lung Cancer
Interventions: OTHER: Best Practice|PROCEDURE: Biospecimen Collection|PROCEDURE: Biospecimen Collection|OTHER: Laboratory Biomarker Analysis|OTHER: Medical Chart Review|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|BEHAVIORAL: Smoking Cessation Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Drug-Eluting Stent Implantation Versus Optimal Medical Treatment in Patients With Chronic Total Occlusion (DECISION-CTO)
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Cypher, xience, Endeavor, Taxus|DRUG: optimal medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Ranibizumab for Exudative Age-related Macular Degeneration
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: DRUG: Ranibizumab 0.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Surgery, Tissue Plasminogen Activator, Antiangiogenic Agents and Age Related Macular Degeneration Complications
Status: COMPLETED
Conditions: Subretinal Haematoma Linked to AMD
Interventions: OTHER: Surgery|OTHER: Intravitreal injections of gas|PROCEDURE: injections of an antiangiogenic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Melatonin vs Pregabalin for Anxiolysis and Sedation
Status: COMPLETED
Conditions: Anxiety
Interventions: DRUG: Melatonin|DRUG: Pregabalin|DRUG: Ondansetron 4 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Aeration, Breathing, Clamping Study 3
Status: ACTIVE_NOT_RECRUITING
Conditions: Preterm Infant|Birth, Preterm
Interventions: PROCEDURE: Physiological-based cord clamping|PROCEDURE: Time-based cord clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glyceryl Trinitrate Versus Lidocaine Cream for IUD Insertion
Status: COMPLETED
Conditions: IUD Insertion
Interventions: DRUG: glyceryl trinitrate cream|DRUG: lidocaine cream|DRUG: placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Procedure Transurethral Needle Ablation (TUNA) and Hospitalization of Short Duration
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: PROCEDURE: Transurethral Needle Ablation (TUNA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Exposure During Endoscopic Retrograde Cholangiopancreatography Between Prone and Left Lateral Decubitus
Status: COMPLETED
Conditions: Exposure to Ionizing Radiation
Interventions: RADIATION: The radiographic-fluoroscopic system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pre-operative Chemotherapy and Radiation Therapy for Esophageal Carcinoma
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: PROCEDURE: Radiation|DRUG: Paclitaxel|DRUG: Cisplatin|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyaluronic Acid Gel in Prevention of Intrauterine Adhesions After Endometrial Ablation
Status: COMPLETED
Conditions: Menorrhagia
Interventions: OTHER: Hyaluronic acid gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessing the Effectiveness of a Water Filter Technology as an Arsenic Mitigation Strategy in West Bengal
Status: COMPLETED
Conditions: Total Urinary Arsenic|Total Arsenic in Water|Diarrhoeal Disease
Interventions: DEVICE: Pureit As+ Filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ketamine Assisted Psychotherapy for Opioid Use Disorder
Status: RECRUITING
Conditions: Opioid-use Disorder
Interventions: COMBINATION_PRODUCT: MORE+KAP|BEHAVIORAL: MORE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Virtual Reality Games on Knee Proprioception After Anterior Cruciate Ligament Reconstruction (ACLR)
Status: COMPLETED
Conditions: Motor Activity|Proprioceptive Disorders|Balance; Distorted
Interventions: PROCEDURE: Wii fit protocol of virtual reality games|PROCEDURE: Regular exercise rehabilitation protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vemurafenib With Lymphodepletion Plus Adoptive Cell Transfer & High Dose IL-2 Metastatic Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Melanoma
Interventions: DRUG: High Dose Interleukin-2 (IL-2)|PROCEDURE: ACT with TIL Infusion|DRUG: Vemurafenib|DRUG: Lymphodepletion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Leronlimab for Mild to Moderate COVID-19
Status: COMPLETED
Conditions: Coronavirus Disease 2019
Interventions: DRUG: Placebo|DRUG: Leronlimab (700mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diet Education Program for Stage I-IV Colorectal Cancer Survivors
Status: COMPLETED
Conditions: Stage I Colorectal Cancer AJCC v8|Stage II Colorectal Cancer AJCC v8|Stage IIA Colorectal Cancer AJCC v8|Stage IIB Colorectal Cancer AJCC v8|Stage IIC Colorectal Cancer AJCC v8|Stage III Colorectal Cancer AJCC v8|Stage IIIA Colorectal Cancer AJCC v8|Stage IIIB Colorectal Cancer AJCC v8|Stage IIIC Colorectal Cancer AJCC v8|Stage IV Colorectal Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8
Interventions: DIETARY_SUPPLEMENT: Dietary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Eustachian Tube Function With 226 and 1000 Hz Probes in Children Undergoing Tonsillectomy ± Adenoidectomy
Status: RECRUITING
Conditions: Tonsillar Hypertrophy|Eustachian Tube Dysfunction|Tympanic Membrane Disorder|Eustachian Tube Dysfunction of Both Ears
Interventions: DIAGNOSTIC_TEST: Eustachian tube function test with 226 and 1000 Hz probes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Resynchronization/Defibrillation for Ambulatory Heart Failure Trial
Status: COMPLETED
Conditions: Heart Failure, Congestive
Interventions: DEVICE: Optimal Medical Therapy plus ICD|DEVICE: Optimal Medical Therapy plus CRT/ICD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of HLX10, a Monoclonal Antibody Targeting Programmed Death-1 (PD-1) in Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Solid Tumor
Interventions: DRUG: HLX10
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TENS for Phantom Limb Pain Prevention Following Major Amputation
Status: UNKNOWN
Conditions: Phantom Limb Pain|Peripheral Vascular Diseases
Interventions: DEVICE: TENS INTERVENTION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Peptides and Chelators on Somatostatin Receptor Antagonists
Status: UNKNOWN
Conditions: Neuroendocrine Tumors
Interventions: DIAGNOSTIC_TEST: 68Ga-NODAGA-LM3 and 68Ga-DOTA-LM3 PET/CT|DIAGNOSTIC_TEST: 68Ga-NODAGA-LM3 and 68Ga-NODAGA-JR11 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prostate Metabolism, Cancer Risk and Gut Microbiota
Status: RECRUITING
Conditions: Prostate Cancer|Prostate Hyperplasia
Interventions: OTHER: MRI scan and laboratory visit|PROCEDURE: Prostate biopsies|PROCEDURE: Radical prostatectomy and blood, urine and tissue sampling|PROCEDURE: TURP and blood, urine and tissue sampling|PROCEDURE: Radical cystoprostatectomy and blood, urine and tissue sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Performing a Low-dose, Whole-body Angiography as the First Element of an Imaging Assessment Following Stroke / TIA
Status: UNKNOWN
Conditions: Stroke|Ischemic Attack, Transient
Interventions: OTHER: Routine Imaging Assessment|DEVICE: LDWBA first (CT scan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Effect of Epidural Analgesia on Intracranial Pressure by Measuring the Optic Nerve Sheath Diameter Using Ultrasound in Pediatric Patients With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DRUG: Bolus group for epidural block|DRUG: Infusion group for epidural block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Cruciate Retaining and Posterior Stabilized Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Arthropathy of Knee Joint
Interventions: PROCEDURE: Total knee replacement with cruciate retaining femoral component|PROCEDURE: Total knee replacement with cruciate substituting femoral component
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Children Toxine Botulinum Detrusor Injection in Neurogenic Vesical Hyperactivity Syndrom: Non Inferiority Multicenter Controlled Therapeutic Study Between Two Reported Weight's Doses
Status: COMPLETED
Conditions: Neurogenic Vesical Hyperactivity Syndrom
Interventions: DRUG: full dose at 16 UI/kg for Dysport or 6,5 UA/kg for Botox|DRUG: half dose at 8 UI/kg for Dysport or 3,25 UA/kg for Botox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Electrical Stimulation of Human Myocytes in Microgravity
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcopenia
Interventions: PROCEDURE: Muscle Tissue Biopsy|OTHER: Maximal Oxygen Consumption (V02max)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CLBR Per Initial Cycle With Different Starting Dose in Aged Patients With Poor Ovarian Reservation: 300IU Versus 150IU
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: 300IU rFSH Gonal-F® starting dose during controlled ovarian stimulation|DRUG: 150IU rFSH Gonal-F® starting dose during controlled ovarian stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Whey and Leucine on Glycaemia in Adults Without Diabetes
Status: UNKNOWN
Conditions: Pre Diabetes
Interventions: DIETARY_SUPPLEMENT: Whey Protein Isolate|DIETARY_SUPPLEMENT: Wheat Protein|DIETARY_SUPPLEMENT: Wheat Protein with Leucine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Accuracy of Percutaneous Biopsy by Vacuum-assisted Biopsy (VAB) to Assess Pathological Complete Response in Patients With Clinical and Radiological Complete Response After Neoadjuvant Chemotherapy (NeoVAB)
Status: RECRUITING
Conditions: Vacuum-assisted Biopsy
Interventions: DIAGNOSTIC_TEST: Vacuum-assisted biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Assess the Safety and Tolerability of BMS-986322 in Healthy Participants of Japanese Descent
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986322|OTHER: Placebo for BMS-986322
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of GCSF in the Treatment of ALS Patients
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Granulocyte Colony Stimulating Factor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Left Atrial Ablation of Paroxysmal Atrial Fibrillation With Implantable Loop Recorder Follow Up Study: The LAAPITUP 2 Study
Status: UNKNOWN
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: ILR insertion|PROCEDURE: AF ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Immunogenicity of Pneumococcal Vaccine 2189242A in Children Aged 12-23 Months at the Time of First Vaccination
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Pneumococcal vaccine GSK2189242A (formulation 1)|BIOLOGICAL: Pneumococcal vaccine GSK2189242A (formulation 2)|BIOLOGICAL: Pneumococcal vaccine GSK2189242A combined with pneumococcal vaccine GSK1024850A (formulation 3)|BIOLOGICAL: Pneumococcal vaccine GSK2189242A combined with pneumococcal vaccine GSK1024850A (formulation 4)|BIOLOGICAL: Pneumococcal vaccine GSK1024850A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sintilimab (One Anti-PD-1 Antibody) Plus Low-dose Bevacizumab for ctDNAlevel- Relapse and Clinical-relapse Oligodendroglioma
Status: RECRUITING
Conditions: Oligodendroglioma
Interventions: DRUG: Tislelizumab plus Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test How BI 1358894 is Taken up in the Body and How Food Influences the Amount of BI 1358894 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1358894
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2951742 (Galcanezumab) in Participants With Cluster Headache
Status: COMPLETED
Conditions: Episodic Cluster Headache|Chronic Cluster Headache
Interventions: DRUG: Galcanezumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glycemic Index of Mango and Pear in Different Solid Products and Drinks
Status: COMPLETED
Conditions: Glucose Intolerance
Interventions: OTHER: Mango puree and pear juice beverage|OTHER: Commercial mango juice|OTHER: Fresh natural mango|OTHER: Frozen natural mango|OTHER: Processed natural mango pulp|OTHER: Mix of natural mango and pear|OTHER: 50 grams glucose load
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose:
Clinical trial: Study of Everolimus and Sorafenib in Patients With Advanced Thyroid Cancer Who Progressed on Sorafenib Alone
Status: UNKNOWN
Conditions: Differentiated Thyroid Cancer
Interventions: DRUG: Everolimus|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances
Status: RECRUITING
Conditions: B-Cell Lymphoma|Myelodysplastic Syndromes (MDS)|Acute Myeloid Leukemia (AML)
Interventions: DRUG: Cyclophosphamide|DRUG: CAR.70/IL15-transduced CB-NK cells|DRUG: Fludarabine phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Baricitinib in the Treatment of Frontal Fibrosing Alopecia (FFA)
Status: RECRUITING
Conditions: Frontal Fibrosing Alopecia
Interventions: DRUG: Baricitinib 4 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Visual and Pressure Biofeedback in Symptomatic Forward Head Posture.
Status: RECRUITING
Conditions: Forward Head Posture
Interventions: OTHER: Cervical Stabilization|DEVICE: Pressure Biofeedback|DEVICE: Visual Biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety of Acute Baclofen in Methadone-maintained Individuals With Opiate Dependence.
Status: UNKNOWN
Conditions: Addiction Opiate
Interventions: DRUG: Baclofen|DRUG: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ultra High Field MRI and MRS Techniques in Diagnosing Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: PROCEDURE: high field strength magnetic resonance imaging|PROCEDURE: magnetic resonance spectroscopic imaging|PROCEDURE: chemical exchange saturation transfer magnetic resonance imaging|PROCEDURE: diffusion-weighted magnetic resonance imaging|PROCEDURE: dynamic contrast-enhanced magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized-controlled Trial of Preoperative Inspiratory Muscle Training on Postoperative Complications
Status: RECRUITING
Conditions: Postoperative Complications|Breathing Exercises|Preoperative Period
Interventions: BEHAVIORAL: preoperative inspiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess BMS-986453 in Participants With Relapsed and/or Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Relapsed and/or Refractory Multiple Myeloma
Interventions: DRUG: BMS-986453|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Busulfan, Cyclophosphamide, & Antithymocyte Globulin Followed by Stem Cell Transplant in Treating Hematologic Cancer
Status: COMPLETED
Conditions: Graft Versus Host Disease|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases|Secondary Myelofibrosis
Interventions: BIOLOGICAL: anti-thymocyte globulin|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: mycophenolate mofetil|DRUG: tacrolimus|GENETIC: polymerase chain reaction|GENETIC: polymorphism analysis|OTHER: flow cytometry|OTHER: laboratory biomarker analysis|OTHER: pharmacogenomic studies|OTHER: pharmacological study|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Out of Plane and In Plane Injection Techniques in Patients With Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|Pain|Carpal Tunnel
Interventions: OTHER: Technique of injection method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does VoltagE Guided Additional Ablation Improve Procedural Outcome of Atrial Fibrillation Ablation?
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Additional posterior wall isolation|PROCEDURE: Voltage-guided substrate homogenization|PROCEDURE: PVI only group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Reactogenicity, and Effectiveness of mRNA-1273 Vaccine in Adolescents 12 to <18 Years Old to Prevent COVID-19
Status: COMPLETED
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: mRNA-1273|BIOLOGICAL: Placebo|BIOLOGICAL: mRNA-1273.222
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intermittent Low Energy Diet in CKD: MIX UP Feasibility Study
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Obesity
Interventions: BEHAVIORAL: 5:2 diet|BEHAVIORAL: Renal Weight Management Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: What Or When to Eat to Reduce the Risk of Type 2 Diabetes (WOW)
Status: COMPLETED
Conditions: Time-restricted Eating|Diet Quality
Interventions: OTHER: Time-restricted eating|OTHER: Current Best Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety and Effectiveness Study of BL-ABT12 Multi-Purpose Solution for Use by Participants With Soft Contact Lenses
Status: COMPLETED
Conditions: Contact Lens Wear
Interventions: DEVICE: ABT12 Multi-Purpose Solution|DEVICE: COMPLETE Multi-Purpose Solution|DEVICE: Sensitive Eyes® Rewetting Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of a Propionate Colon Release Form on ad Libitum Eating and Appetite Perception
Status: COMPLETED
Conditions: Overweight
Interventions: DIETARY_SUPPLEMENT: Ca-propionate 1 g|DIETARY_SUPPLEMENT: Ca-propionate 3 g|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Deprescribing Proton Pump Inhibitors to Reduce Post-TIPS Hepatic Encephalopathy
Status: RECRUITING
Conditions: Hepatic Encephalopathy
Interventions: DRUG: PPI deprescribing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Aha BOOST Arm-hand BOOST Therapy to Enhance Recovery After Stroke: Clinical, Health Economic and Process Evaluation
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: Arm-hand BOOST|OTHER: Lower limb BOOST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Controlled Clinical Trial to Determine the Effective Dose of Cocoa in Lowering Blood Pressure
Status: COMPLETED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: Delivery and return of chocolate|PROCEDURE: Determination of blood pressure|PROCEDURE: Anthropometric Measurements|PROCEDURE: Food Anamnesis|PROCEDURE: Samples: serological tests and culture of mononuclear cells|PROCEDURE: Analysis of cytokine production
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Zingiber Officinale Roscoe Extract on Body Fat
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Zingiber officinale Roscoe extract 200 mg|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Community-based Advance Care Planning Programme for Patients With Advanced Disease
Status: COMPLETED
Conditions: Chronic Disease
Interventions: BEHAVIORAL: Advance care planning programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Vitamin D Deficiency in Chronic Kidney Disease (CKD) Patients
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism|Chronic Kidney Disease
Interventions: DRUG: Paricalcitol|DRUG: Ergocalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Storytelling in Symptom Management Pediatric Oncology
Status: RECRUITING
Conditions: Child, Only|Cancer|Symptoms and Signs|Narration
Interventions: OTHER: Digital Storytelling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Obstructive Sleep Apnea Treatment on Cardiovascular Events in Patients With Acute Cardiogenic Pulmonary Edema: CPAP-CARE STUDY.
Status: TERMINATED
Conditions: Obstructive Sleep Apnea|Pulmonary Edema Cardiac Cause
Interventions: DEVICE: CPAP|DEVICE: Nasal Strips
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Dyspepsia Treatment Trial
Status: COMPLETED
Conditions: Dyspepsia and Other Specified Disorders of Function of Stomach
Interventions: DRUG: Amitriptyline|DRUG: Escitalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Lens Care Regimens With a Silicone Hydrogel Lens (Emerald)
Status: COMPLETED
Conditions: Myopia
Interventions: DRUG: ClearCare|DRUG: Optifree Replenish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Positive Parenting: Empowering Young Mothers Experiencing Homelessness With a History of Inter-personal Violence to Improve Parenting Strategies
Status: COMPLETED
Conditions: Positive Parenting
Interventions: OTHER: Recovering from Intimate partner violence through Strengths and Empowerment (RISE)|OTHER: ePALS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Autofluorescent Flavoprotein Imaging of Intraepidermal Nerve Fibers: a Pilot Study
Status: COMPLETED
Conditions: Small Fiber Neuropathy
Interventions: DEVICE: AFI microscope|DEVICE: negative control 1: lidocaine/prilocaine|DEVICE: negative control 2: 8% capsaicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC