pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Antiandrogen Therapy, Abiraterone Acetate, and Prednisone With or Without Neutron Radiation Therapy in Treating Patients With Prostate Cancer
Status: TERMINATED
Conditions: Castration-Sensitive Prostate Carcinoma|Metastatic Malignant Neoplasm in the Bone|Metastatic Prostate Carcinoma|Prostate Adenocarcinoma|Prostate Small Cell Neuroendocrine Carcinoma|Stage IV Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: DRUG: Antiandrogen Therapy|DRUG: Abiraterone Acetate|DRUG: Prednisone|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-density EEG in Neurological Disorders
Status: ENROLLING_BY_INVITATION
Conditions: Epilepsy|Tumor|Healthy
Interventions: DIAGNOSTIC_TEST: High-density electroencephalogram (HD-EEG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Iron and Vitamin E Supplementation on Disease Activity in Patients With Either Crohn's Disease or Ulcerative Colitis
Status: TERMINATED
Conditions: Crohn's Disease|Ulcerative Colitis|Mild or Moderate Anaemia
Interventions: DRUG: Iron supplement 300-600 mg/day|DRUG: Vitamin E 800IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Viveye Ocular Magnetic Neurostimulation System (OMNS) for the Management of Severe Dry Eye Disease
Status: TERMINATED
Conditions: Dry Eye Syndromes|ATD|Sjogren's Syndrome
Interventions: DEVICE: Viveye OMNS treatment|DEVICE: Viveye OMNS sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutri Diet Goal Setting Software Pilot Trial
Status: COMPLETED
Conditions: Type 2 Diabetes|Pre-diabetes|Metabolic Syndrome
Interventions: BEHAVIORAL: Collaborative Diet Goal Setting Clinical Decision Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ipilimumab With or Without High-Dose Recombinant Interferon Alfa-2b in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Melanoma|Stage IIIA Cutaneous Melanoma AJCC v7|Stage IIIB Cutaneous Melanoma AJCC v7|Stage IIIC Cutaneous Melanoma AJCC v7|Stage IV Cutaneous Melanoma AJCC v6 and v7
Interventions: BIOLOGICAL: Ipilimumab|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Recombinant Interferon Alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cold Versus Hot Adenoidectomy for Obstructive Sleep Apnea in Pediatric Patients
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Adenoid; Growth
Interventions: PROCEDURE: adenoidectomy - cold method|PROCEDURE: adenoidectomy - hot method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Neural Correlates of Cognitive Rehabilitation in Post-Traumatic Stress Disorder (PTSD)
Status: TERMINATED
Conditions: Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: cognitive training|BEHAVIORAL: video game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Dose Study of PRT064445, a Factor Xa (fXa) Inhibitor Antidote
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: PRT064445|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: GP Combined With Nimotuzumab and Sintilimab as Induction Therapy for Nasopharyngeal Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Nasopharyngeal Carcinoma
Interventions: DRUG: GP Regimen, Nimotuzumab, Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Safety Study of Adjuvanted Swine Origin A (H1N1) Pandemic Subunit Egg Derived Vaccine
Status: COMPLETED
Conditions: Pandemic Influenza A (H1N1)|A New Flu Virus of Swine Origin
Interventions: OTHER: Non-intervention observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of High Fat Diet on the Pharmacokinetics of AD16 Tablets in Healthy Chinese Adult Subjects
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: OTHER: high-fat diet group（AD16 20mg）|OTHER: fasted group（AD16 20mg）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: R115777 to Treat Children With Neurofibromatosis Type 1 and Progressive Plexiform Neurofibromas
Status: COMPLETED
Conditions: Neurofibroma, Plexiform|Neurofibromatosis Type I
Interventions: DRUG: tipifarnib|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Correlation Between 3 Phase Bone Scintigraphy and Pressure Pain Thresholds in Patients With Complex Regional Pain Syndrome (CRPS)
Status: COMPLETED
Conditions: Complex Regional Pain Syndrome Type I of the Upper Limb|Unilateral Limb Pain of Other Origin|Healthy Subjects
Interventions: PROCEDURE: Pressure Pain measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With Pathology
Status: RECRUITING
Conditions: Head and Neck Cancer|Squamous Cell Carcinoma (SCC) of the Oral Cavity
Interventions: DEVICE: Reflectance Confocal Microscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy of Computerized Cognitive Training in Adults With ADHD: Change in ADHD Symptoms, Executive Functions and Quality of Life Following Three Months of Training.
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: cognitive computerized training|BEHAVIORAL: simple cognitive computerized training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NanOss Bioactive With Autograft and Bone Marrow Aspirate in the Posterolateral Spine
Status: WITHDRAWN
Conditions: Lumbar Spinal Stenosis Secondary to Other Disease
Interventions: DEVICE: nanOSS|DEVICE: Autograft
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Cetuximab in Combination With Carboplatin-Paclitaxel in Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: BIOLOGICAL: cetuximab|DRUG: paclitaxel|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CPAP Versus Bi-level in Chronic Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DIAGNOSTIC_TEST: Shuttle walk test|DEVICE: Noninvasive ventilation (Bi-pap)|DEVICE: Noninvasive ventilation (CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of a Behavioral Team Intervention for Obsessive Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: BEHAVIORAL: Team ERP (T-ERP) Intervention|BEHAVIORAL: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Quetiapine and Mirtazapine for the Treatment of Alcohol Dependency
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: Mirtazapine|DRUG: Quetiapine fumarate extended release (Quetiapine XR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irinotecan Followed by Fluorouracil in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: fluorouracil|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant/Adjuvant Chemotherapy, Vaccine & Adjuvant Radiation Therapy in p53-Overexpressing Stage III Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: autologous dendritic cell-adenovirus p53 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Yoghurts Enriched With XXS (Mixture of Natural Polyphenolic Compounds and Plant Extracts) on the Evolution of Weight in Overweight Subjects
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DIETARY_SUPPLEMENT: yoghurts enriched with XXS|DIETARY_SUPPLEMENT: yoghurts non enriched with XXS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Treatment of a Resistant Disease Using Decitabine Combined With Vemurafenib Plus Cobimetinib
Status: TERMINATED
Conditions: Metastatic Melanoma|Melanoma|BRAF-mutated Metastatic Melanoma|V600EBRAF-mutated Metastatic Melanoma
Interventions: DRUG: Vemurafenib + Cobimetinib, Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Laparoscopic Transcystic Biliary Drainage in the Management of Cholecystocholedocholithiasis
Status: NOT_YET_RECRUITING
Conditions: Common Bile Duct Calculi|Acute; Cholecystitis, Choledocholithiasis|Acute Cholecystitis With Obstruction|Acute Cholangitis
Interventions: PROCEDURE: Modified laparoscopic transcystic biliary drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Intervention for Adolescent Girls in Karnataka
Status: COMPLETED
Conditions: Secondary School Entry and Completion|Child Marriage
Interventions: BEHAVIORAL: Multi-level, structural and norms-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Establishing Lymphedema and Fibrosis Measures in Oral Cancer Patients
Status: COMPLETED
Conditions: Oral Cavity Cancer|Oropharyngeal Cancer|Lymphedema|Fibrosis
Interventions: OTHER: LEF measures|PROCEDURE: Technical measure|PROCEDURE: Technical measure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anastrozole and ZD1839 Compared With Fulvestrant and ZD1839 in Postmenopausal Women w/ Metastatic Breast Cancer
Status: COMPLETED
Conditions: Estrogen Receptor-positive Breast Cancer|Progesterone Receptor-positive Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: anastrozole|DRUG: gefitinib|DRUG: fulvestrant|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Colostrum and Its Effect on Immune System
Status: UNKNOWN
Conditions: Immune System Diseases|Premature Infant Disease|Immunoglobulin Deficiency
Interventions: BIOLOGICAL: Orally Colostrum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Neurologic Manifestations of the Arbovirus Infection in Colombia
Status: COMPLETED
Conditions: Encephalitis|Myelitis|Guillain-Barre Syndrome|Cranial Nerve Palsies|Meningitis|Zika Virus Infection|Dengue (Virus); Fever, Sandfly|Chikungunya Fever
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Changes in Blood Lipids After Long-term Consumption of n-3 LC-PUFA-Enriched Dairy Products
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DIETARY_SUPPLEMENT: n-3 LC-PUFA|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy/Safety of IPI-549 in Combination With Nivolumab in Patients With Advanced Urothelial Carcinoma (MARIO-275)
Status: COMPLETED
Conditions: Bladder Cancer|Urothelial Carcinoma|Solid Tumor|Advanced Cancer
Interventions: DRUG: IPI-549 (eganelisib)|DRUG: Nivolumab|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Sunosi® PK in Breast Milk and Plasma of Healthy Postpartum Women Following Single Dose Oral Administration
Status: COMPLETED
Conditions: Narcolepsy|Obstructive Sleep Apnea|Excessive Daytime Somnolence|Excessive Sleepiness|Postpartum
Interventions: DRUG: Solriamfetol 150 mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Chemotherapy and Autologous Transplant for Breast Cancer
Status: UNKNOWN
Conditions: Graft vs Host Disease
Interventions: PROCEDURE: high dose chemo and auto hematopoietic cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Locally Advanced NSCLC Radiotherapy Pneumonia by Inhaling Beclomethasone Propionate
Status: UNKNOWN
Conditions: Locally Advanced Non Small Cell Lung Cancer
Interventions: DRUG: Beclomethasone propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Probucol and/or Cilostazol on Mean IMT in Patients With Coronary Heart dIsease
Status: COMPLETED
Conditions: Hyperlipidemias
Interventions: DRUG: HMG-CoA Reductase Inhibitor|DRUG: Probucol|DRUG: Cilostazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Vespireit, Sustained-release Tablets, in Patients With Autonomic Dysfunction Syndrome Accompanied by Functional Vertigo
Status: RECRUITING
Conditions: Vertigo|Autonomic Dysfunction
Interventions: DRUG: Vespireit|DRUG: Arlevert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation for Methadone Maintenance Therapy Combined With Methamphetamine Abuse
Status: COMPLETED
Conditions: Methamphetamine Abuse
Interventions: DEVICE: repetitive transcranial magnetic stimulation (rTMS)|DEVICE: sham repetitive transcranial magnetic stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Contact Sensitization Potential Of Tazarotene Foam On Skin In Healthy Volunteers
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Tazarotene Foam|DRUG: Vehicle Foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Detection of Asymptomatic Atrial Fibrillation in Persons of 65 Year of Age or Older
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: OTHER: Subjects with asymptomatic atrial fibrillation will be screened by using a Mobile ECG Device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact of Pedagogical Framework in Education of Neonatal Resuscitation
Status: COMPLETED
Conditions: Nursing Students Education on Neonatal Resuscitation
Interventions: OTHER: Pedagogical Framework (Learn, See, Practice, Prove, Do, and Maintain)|OTHER: Traditional Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Determinants of Implementation Success Coordinating Ventilator, Early Ambulation and Rehabilitation Efforts
Status: WITHDRAWN
Conditions: Implementation Science|Delirium|Intensive Care Unit Acquired Weakness|Pain|Sedation Complication|Mechanical Ventilation Complication
Interventions: OTHER: Survey and concept mapping
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I Study to Assess the Safety and Immunology of a COVID-19 Vaccine With GRAd-COV2 Vaccine
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: GRAd-COV2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Post Gingival Depigmentation Assessment: Comparison of Surgical Stripping vs (Er,Cr:YSGG) Laser
Status: COMPLETED
Conditions: Pigmentation|Gingiva
Interventions: PROCEDURE: Gingival depigmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trail To Evaluate the Immune Effects of Primary and Booster Immunizations With Poliovirus Vaccine
Status: UNKNOWN
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: bOPV(Candy)|BIOLOGICAL: bOPV(Liquid)|BIOLOGICAL: bOPV(Liquid)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of a LAMA and a uLABA on the Methacholine Dose-response Curve
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Glycopyrronium|DRUG: Indacaterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Pelvic Floor Function With Transcranial Magnetic and Tibial Nerve Stimulation for Neurogenic Bladder in MS
Status: NOT_YET_RECRUITING
Conditions: Neurogenic Overactive Bladder|Multiple Sclerosis
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation and Percutaneous Tibial Nerve Stimulation|DEVICE: Repetitive Transcranial Magnetic Stimulation|DEVICE: Percutaneous Tibial Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pericapsular Nerve Group Block Applied in Patients Undergoing Hip Fracture Surgery.
Status: RECRUITING
Conditions: Hip Fractures|Pain, Postoperative
Interventions: PROCEDURE: Pericapsular Nerve Group (PENG) Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Human COVID-19 Immunoglobulin (COVID-HIG) Therapy for COVID-19 Patients
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: Human COVID-19 immunoglobulin (pH4) for intravenous injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib in Combination With Rituximab in Patients With Indolent Clinical Forms of MCL
Status: ACTIVE_NOT_RECRUITING
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: IBRUTINIB|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genotype Guided Versus Conventional Approach in Selection of Oral P2Y12 Receptor Blocker in Chinese Patients Suffering From Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Clopidogrel|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Postmortem Pulmonary Interstitial Fibrosis Severity and EGFR Positivity in Covid-19 Pneumonia
Status: UNKNOWN
Conditions: Pneumonia, Viral|COVID-19 Pneumonia|EGFR Amplification
Interventions: PROCEDURE: None involvement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hydroxyurea Therapy: Optimizing Access in Pediatric Populations Everywhere
Status: TERMINATED
Conditions: Sickle Cell Disease|Thalassemia
Interventions: DRUG: Hydroxyurea|DRUG: Hydroxyurea Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Vitamin D3 Supplementation on Cognitive Function in Community Dwelling Older Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol -Vitamin D3|OTHER: Placebo -gel capsule containing no vitamin D.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Exploratory Study on the Paclitaxel + S-1 + Oxaliplatin (PSOX) for Locally Advanced or Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Paclitaxel + S-1 + Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chitosan Versus Glucosamine Phonophoresis in the Management of Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis|Knee Arthritis
Interventions: DEVICE: Phonophoresis with chitosan|DEVICE: Phonophoresis with glucoasmine|PROCEDURE: Conventional Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study in Women on the Effect of JNJ-64530440 on Oral Contraceptive and Midazolam, and the Effect of a High-fat Meal on JNJ-64530440
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: Drospirenone/Ethinylestradiol|DRUG: Midazolam|DRUG: JNJ-64530440
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Once-Daily Asenapine for Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Asenapine 10 mg daily in the evening|DRUG: Asenapine 5 mg twice daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buccal Cortical Separation and Lateralization for Horizontal Ridge Augmentation
Status: COMPLETED
Conditions: Horizontal Ridge Deficiency
Interventions: PROCEDURE: Lateralized buccal cortex with xenograft|PROCEDURE: Lateralized buccal cortex with autogenous particulate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of Radiation Therapy to Immunotherapy for Stage IV Non-Small Cell Lung Cancer Patients Who Are PD-L1 Negative
Status: RECRUITING
Conditions: Lung Adenocarcinoma|Lung Adenosquamous Carcinoma|Lung Non-Small Cell Carcinoma|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|BIOLOGICAL: Ipilimumab|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Nivolumab|PROCEDURE: Positron Emission Tomography|OTHER: Quality-of-Life Assessment|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collaborative Cognitive Behavioral Therapy / Hypnotherapy for Treatment of Pediatric Functional Gastrointestinal Disease
Status: WITHDRAWN
Conditions: Irritable Bowel Syndrome (IBS)
Interventions: BEHAVIORAL: CBT/ Hypnotherapy|DRUG: Routine Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial Photodynamic Therapy on Teeth With Molar Incisor Hypomineralization
Status: UNKNOWN
Conditions: Molar Incisor Hypomineralization
Interventions: RADIATION: aPDT|PROCEDURE: ART
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Treanda™ (Bendamustine HCl) in Patients With Indolent Non-Hodgkin's Lymphoma (NHL) Who Are Refractory to Rituximab
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Bendamustine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Strategies to Assess Anal Cancer Risk In Women
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV)|Human Papillomavirus (HPV)
Interventions: PROCEDURE: Perianal and Digital Anorectal Exam|PROCEDURE: Cervical Swabs|PROCEDURE: Anal Swabs|PROCEDURE: High Resolution Anoscopy (HRA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sorafenib, Carboplatin, and Paclitaxel in Treating Patients With Stage IV Melanoma of the Eye
Status: COMPLETED
Conditions: Ciliary Body and Choroid Melanoma, Medium/Large Size|Extraocular Extension Melanoma|Iris Melanoma|Metastatic Intraocular Melanoma|Recurrent Intraocular Melanoma
Interventions: DRUG: carboplatin|DRUG: paclitaxel|DRUG: sorafenib tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of High-flow Nasal Cannula Therapy in the Treatment of Acute Carbon Monoxide Poisoning
Status: UNKNOWN
Conditions: Carbon Monoxide Poisoning
Interventions: DEVICE: High-flow nasal cannula device|DEVICE: Non-rebreathing oxygen mask group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Niraparib, Abiraterone Acetate and Prednisone for mHSPC With Deleterious Homologous Recombination Repair Alterations
Status: NOT_YET_RECRUITING
Conditions: Metastatic Hormone-sensitive Prostate Cancer (mHSPC)|Deleterious HRR Gene Mutation|BRCA1 Gene Mutation|BRCA2 Gene Mutation|BRIP1 Gene Mutation|CHEK2 Gene Mutation|FANCA Gene Mutation|PALB2 Gene Mutation|RAD51B Gene Mutation|RAD54L Gene Mutation
Interventions: DRUG: Androgen Deprivation Therapy (ADT)|DRUG: Niraparib/Abiraterone Acetate DAT|DRUG: Abiraterone Acetate|DRUG: Prednisone|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Prehabilitation Improve Outcomes in Patients Undergoing Complex Spine Fusion Surgery?
Status: TERMINATED
Conditions: Lumbar Spine Injury|Spinal Fusion|Frailty|Prehabilitation|Nutritional Supplementation|Functional Outcome
Interventions: OTHER: Multimodal Prehabilitation|OTHER: Standard Pre-Surgical Clinical Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hemodilution on Intraoperative Allogeneic Transfusion (HEAL)
Status: RECRUITING
Conditions: Acute Normovolemic Hemodilution|Bone Tumor|Goal-Directed Fluid Therapy|Transfusion
Interventions: PROCEDURE: acute normovolemic hemodilution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Gastric Cancer Asian Phase I Study
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)|DRUG: Sorafenib (Nexavar, BAY43-9006)|DRUG: Sorafenib (Nexavar, BAY43-9006)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Reticulocyte Ratio and Neutrophil / Lymphocyte Ratio in the Diagnosis of Ventilator-associated Pneumonia
Status: SUSPENDED
Conditions: Ventilator-associated Pneumonia (VAP)
Interventions: DIAGNOSTIC_TEST: reticulocyte/hemoglobin (Ret-He) ratio
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Longterm Efficiency and Safety of Intravitreal Injections With Bevacizumab in Patients With Neovascularisation or Macular Edema
Status: RECRUITING
Conditions: Retinal Neovascularization|Macular Edema
Interventions: DRUG: Bevacizumab Injection [Avastin]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Whether Survodutide (BI 456906) Helps Chinese People Living With Overweight or Obesity to Lose Weight
Status: RECRUITING
Conditions: Obesity|Overweight
Interventions: DRUG: survodutide|DRUG: Placebo matching BI 456906
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-calculus Efficacy of a Dentrifice Containing Sodium Pyrophosphate and Potassium Pyrophosphate in Heavy Calculus Formers
Status: COMPLETED
Conditions: ANTICALCULUS EFFICACY OF PYROPHOSPHATE IN HEAVY CALCULUS FORMERS
Interventions: DRUG: DENTRIFICE CONTAINING 5% SODIUM AND POTASSIUM PYROPHOSPHATE|DRUG: PLACEBO DENTRIFICE WITHOUT PROPHOSPHATE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Can Early Initiation of Rehabilitation With Wearable Sensor Technology Improve Outcomes in mTBI?
Status: ACTIVE_NOT_RECRUITING
Conditions: Mild Traumatic Brain Injury|Balance; Distorted|Gait, Unsteady|Quality of Life|Veterans
Interventions: BEHAVIORAL: Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Intralesional Injection of Triamcinolone Acetonide for Desmoid Tumors
Status: COMPLETED
Conditions: Fibromatosis
Interventions: DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CGM Use in COVID19 Patients (Infection With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2))
Status: COMPLETED
Conditions: Diabetes Mellitus|Covid19
Interventions: DEVICE: Continuous Glucose Monitor (CGM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: GCWB1176 Evaluates the Effectiveness and Safety of Immune Function
Status: RECRUITING
Conditions: Immune Function
Interventions: DIETARY_SUPPLEMENT: Lactococcus lactis|OTHER: maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study Evaluating the Safety and Efficacy of Cobimetinib Plus Atezolizumab in BRAFV600 Wild-type Melanoma With Central Nervous System Metastases and Cobimetinib Plus Atezolizumab and Vemurafenib in BRAFV600 Mutation-positive Melanoma With Central Nervous System Metastases
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: DRUG: Cobimetinib|DRUG: Atezolizumab|DRUG: Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study of CT120 in Patient With Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma
Status: NOT_YET_RECRUITING
Conditions: B-cell Non-Hodgkin's Lymphoma
Interventions: DRUG: Fully Human Anti-CD19/CD22 Dual Target Chimeric Antigen Receptor Autologous T Cell Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of MEDI4736 (Durvalumab) With or Without Tremelimumab Versus Standard of Care Chemotherapy in Urothelial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Urothelial Cancer
Interventions: DRUG: MEDI4736 (Durvalumab)|DRUG: Tremelimumab|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Mechanism of Exenatide on Improving Heart Function in Type 2 Diabetes With Heart Failure Patients
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus|Heart Failure
Interventions: DRUG: Exenatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rifaximin for the Secondary Prevention of Spontaneous Bacterial Peritonitis Recurrence in Cirrhotic Patients
Status: WITHDRAWN
Conditions: Spontaneous Bacterial Peritonitis
Interventions: DRUG: Rifaximin|DRUG: Ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Stentys Coronary Stent System Clinical Trial in Patients With Acute Myocardial Infarction
Status: TERMINATED
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: STENTYS self-apposing stent|DEVICE: VISION balloon-expandable stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Dose and Electroencephalography Trial of GATE-202 in Healthy Volunteers
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: apimostinel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HOPE for Human Extended Criteria and Donation After Brain Death Donor (ECD-DBD) Liver Allografts
Status: COMPLETED
Conditions: Hepatocellular Injury|Liver Transplant
Interventions: DEVICE: Hypothermic oxygenated perfusion (HOPE)|PROCEDURE: Conventional cold storage (CCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manual Therapy vs Stretching vs Routine Physical Therapy in Nonspecific Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Routine physical therapy|OTHER: Manual physical therapy with routine physical therapy|OTHER: Stretching physical therapy with routine physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate PK and Safety With Uproleselan Combined With Chemotherapy to Treat Chinese R/R AML Patients
Status: UNKNOWN
Conditions: Relapsed/Refractory AML
Interventions: DRUG: Uproleselan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Diagnostic Feature in a Cardiac Resynchronization Therapy (CRT) Device
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DEVICE: Paradym CRT + Physiological Diagnosis (PhD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Two Different Concentrations of Local Anesthetic in Patient Reported Pain in Oculoplastic Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Dermatochalasis|Dermatochalasis of Eyelid|Dermatochalasis of Both Upper Eyelids|Dermatochalasis of Both Eyes|Dermatochalasis of Right Upper Eyelid|Dermatochalasis of Left Upper Eyelid|Pain
Interventions: DRUG: Full strength lidocaine with epinephrine|DRUG: Dilute lidocaine with epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sitagliptin Versus Sulphonylurea in Type 2 Diabetes During Ramadan
Status: TERMINATED
Conditions: Diabetes|Hypoglycemia
Interventions: DRUG: Sitagliptin|DRUG: sulphonylurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of the Combination of Tropifexor & Licogliflozin and Each Monotherapy, Compared With Placebo in Adult Patients With NASH and Liver Fibrosis.
Status: TERMINATED
Conditions: Non Alcoholic Steatohepatitis (NASH)
Interventions: DRUG: Tropifexor|DRUG: Licogliflozin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Safety and Efficacy of Traditional Chinese Medicine in Sjögren's Syndrome.
Status: COMPLETED
Conditions: Sjögren's Syndrome
Interventions: DRUG: TCM (Gan-Lu-Yin)GLY|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Artificial Intelligence-assisted Screening of Malignant Pigmented Tumors on the Ocular Surface
Status: COMPLETED
Conditions: Orbital Neoplasms|Conjunctival Neoplasms|Eye Neoplasms
Interventions: DIAGNOSTIC_TEST: screening system for ocular surface malignant tumors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Valuation of Variable Dose of Docosahexanoic Acid for the Improvement of the Parameters of Male Fertility
Status: COMPLETED
Conditions: Male Infertility
Interventions: DIETARY_SUPPLEMENT: DHA|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Proof-of-Concept Clinical Pharmacology Trial for COVID-19 Antigen Presentation Therapeutic Biologics
Status: ACTIVE_NOT_RECRUITING
Conditions: Covid19
Interventions: BIOLOGICAL: COVID-19 Therapeutic Biologics - Spike-GM-CSF Protein Lactated Ringer's Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Body and Social Behavior
Status: RECRUITING
Conditions: Psychology, Social|Inflammation|Defeat, Social|Interaction, Social
Interventions: BIOLOGICAL: Influenza vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Radial Extracorporeal Shockwave Therapy in Patients With Chronic Low Back Pain
Status: RECRUITING
Conditions: Chronic Low-back Pain (cLBP)
Interventions: PROCEDURE: radial extracorporeal shockwave therapy_4000_20|PROCEDURE: radial extracorporeal shockwave therapy_500_2|PROCEDURE: standard multimodal pain therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Saline Enhanced Radiofrequency (SERF) Needle Ablation for Refractory VT
Status: NOT_YET_RECRUITING
Conditions: Refractory Ventricular Tachycardia
Interventions: DEVICE: Saline Enhanced Radiofrequency (SERF) Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Liposomal Bupivacaine Under ERAS Concept for Postoperative Analgesia of Ultrasound-Guided QLB in Gynecologic Laparoscopic Patients: A Randomized, Single-blind, Active-Controlled Clinical Study
Status: RECRUITING
Conditions: Pharmacological Action
Interventions: DRUG: Ropivacaine injection|DRUG: Bupivacaine liposome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Chewing the Tapioca Pearls in Bubble Tea Drinks
Status: COMPLETED
Conditions: Saliva
Interventions: OTHER: chewing tapioca pearls in bubble tea drinks|OTHER: drink tea without chewing tapioca pearls
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: IIT CTI Bendamustine, Rituximab, Pixantrone in Relapsed/Refractory B Cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Bendamustine + Rituximab + Pixantrone|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy With or Without Surgical Resection in Locally Advanced Esophageal Cancer
Status: COMPLETED
Conditions: Esophagus Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Anti-CEA CAR-T + Chemotherapy VS Chemotherapy Alone in Patients With CEA+Pancreatic Cancer & Liver Metastases
Status: WITHDRAWN
Conditions: Malignant Tumor of Pancreas Metastatic to Liver
Interventions: BIOLOGICAL: Anti-CEA CAR-T cells|DRUG: gemcitabine/nab paclitaxel|DRUG: NLIR+FU/FA|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy/Safety of ALTB-268 in Subjects w/Moderately to Severely Active UC Refractory to Biologics
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: BIOLOGICAL: ALTB-268
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Roadmap 2.0 in Oncology Caregivers and Patients
Status: COMPLETED
Conditions: Cancer|Quality of Life
Interventions: BEHAVIORAL: Roadmap 2.0 information system|OTHER: Wearable activity sensor|OTHER: Survey administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Efficacy of Guardian Connect to Modify Lifestyle in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: Guardian connect|DEVICE: iPro2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gonyautoxin 2/3 in the Treatment of Acute Back Pain: A Clinical Proof-of-concept Study
Status: COMPLETED
Conditions: Back Pain|Acute Pain
Interventions: DRUG: GTX 2/3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DF4 Master Study (Safety and Efficacy Study)
Status: COMPLETED
Conditions: Ventricular Tachycardia|Ventricular Fibrillation|Sudden Cardiac Death|Heart Failure
Interventions: DEVICE: Iforia/Ilesto ICD/CRT-D, Linox smart DF4 lead/ Protego
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A First in Human Study of IBC-Ab002 in Persons With Early Alzheimer's Disease (AD)
Status: RECRUITING
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: IBC-Ab002|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zinc Supplementation in Children With Sickle Cell Disease in Western Kenya
Status: COMPLETED
Conditions: Sickle Cell Disease|Zinc Deficiency|Infection
Interventions: DIETARY_SUPPLEMENT: Zinc Sulfate Tablets|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Low-FODMAPs Dietary Therapy for Irritable Bowel Syndrome in China
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Diet Modification
Interventions: DIETARY_SUPPLEMENT: low-FODMAPs diet|DIETARY_SUPPLEMENT: Traditional dietary advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Simultaneous RZV and aIIV4 Vaccination
Status: COMPLETED
Conditions: Pain|Quality of Life|Injection Site Reaction|Adverse Drug Event
Interventions: BIOLOGICAL: FLUAD® Quadrivalent|BIOLOGICAL: Fluzone® High-Dose Quadrivalent|BIOLOGICAL: SHINGRIX®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intraoperative Video Laryngoscopy as Adjunct for Nerve Monitoring
Status: COMPLETED
Conditions: Vocal Cord Function in Neck Procedures
Interventions: DEVICE: Intraoperative Video Laryngoscopy|DRUG: Glycopyrrolate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CorONa Virus edoxabaN ColchicinE (CONVINCE) COVID-19
Status: TERMINATED
Conditions: SARS-CoV Infection|COVID-19
Interventions: DRUG: Edoxaban Tablets|DRUG: Colchicine Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ridge Splitting With Implant Placement Using Autogenous Tooth Graft
Status: COMPLETED
Conditions: Dental Implant Failure Nos|Alveolar Bone Loss|Peri-Implantitis
Interventions: PROCEDURE: autogenous tooth graft|PROCEDURE: autogenous bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT