pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Impact of the Immune System on Response to Anti-Coronavirus Disease 19 (COVID-19) Vaccine in Allogeneic Stem Cell Recipients (Covid Vaccin Allo)
Status: UNKNOWN
Conditions: Coronavirus Disease 2019 (Covid19)|Hematopoietic Neoplasms
Interventions: DRUG: anti-COVID19 mRNA-based vaccine (BNT162b2, Comirnaty®, commercialized by Pfizer)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of the Safety and Pharmacokinetics of MINT1526A, Administered Intravenously As a Single Agent and in Combination With Bevacizumab to Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Cancers
Interventions: DRUG: MINT1526A|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Antibiotic Therapy in Children With Acute Uncomplicated Febrile Urinary Tract Infection
Status: COMPLETED
Conditions: Febrile Urinary Tract Infection
Interventions: OTHER: Individualized antibiotic therapy|OTHER: Standard antibiotic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Boost Radiotherapy With Electrons (IOERT) Followed By Hypofractionated Whole-Breast Irradiation (WBRT)
Status: UNKNOWN
Conditions: Invasive Lobular and Ductal Carcinoma
Interventions: RADIATION: Hypofractionated Whole Breast Radiation Therapy|RADIATION: Intraoperative Electron Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation in Older Women
Status: COMPLETED
Conditions: Osteoporosis|Aging
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Calcium Citrate (Citracal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: L-CARnitine in the Palliative Treatment of Advanced PANcreatic Cancer (CARPAN)
Status: SUSPENDED
Conditions: Pancreatic Carcinoma
Interventions: DIETARY_SUPPLEMENT: L-Carnitine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: INV-144 Versus Losartan in Hypertension and Type 2 Diabetes Mellitus Patients With Macroalbuminuria
Status: COMPLETED
Conditions: Hypertension|Diabetes Mellitus, Type 2
Interventions: DRUG: Active Control|DRUG: INV-144
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of GET73 on MRS Measures of Central Glutamate and GABA in Individuals With Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: GET73|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 3B, Open Label, Multi-Center Study to Evaluate the Safety, Tolerability and Immunogenicity of Novartis Meningococcal B Recombinant Vaccine When Administered Alone to Healthy Infants According to Different Immunization Schedules and to Healthy Children Aged 2 to 10 Years
Status: COMPLETED
Conditions: Meningococcal Disease|Meningococcal Meningitis
Interventions: BIOLOGICAL: rMenB + OMV NZ vaccine|BIOLOGICAL: rMenB + OMV NZ vaccine|BIOLOGICAL: rMenB + OMV NZ vaccine|BIOLOGICAL: rMenB + OMV NZ vaccine|BIOLOGICAL: Meningococcal C oligosaccharide conjugated vaccine|BIOLOGICAL: Pneumococcal polysaccharide conjugate vaccine, 10 valent adsorbed.|BIOLOGICAL: rMenB + OMV NZ vaccine|BIOLOGICAL: rMenB + OMV NZ vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Long-term Value of Preoperative Duplex Before Surgery for Varicose Veins
Status: COMPLETED
Conditions: Varicose Veins
Interventions: PROCEDURE: preoperative duplex examination|PROCEDURE: Preoperative duplex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Photobiomodulation for Prevention of Chemotherapy-induced Peripheral Neuropathy in Women With Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Peripheral Nervous System Diseases AND Breast Neoplasms
Interventions: DEVICE: Intervention group with the IV and V LED board|DEVICE: Intervention group with the IV, V and Violet LED board|DEVICE: Control group with LED board without emitting light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Targeting Microvascular Dysfunction in Young Hypertensive Patients
Status: WITHDRAWN
Conditions: Hypertension
Interventions: DRUG: Simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of SH229 in Patients With HCV Infection
Status: COMPLETED
Conditions: HCV Infection
Interventions: DRUG: SH229|DRUG: Placebos|DRUG: SH229|DRUG: Placebos|DRUG: SH229|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hormone Therapy in Treating Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Sexual Dysfunction and Infertility
Interventions: DRUG: finasteride|DRUG: flutamide|OTHER: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Study Of Ertugliflozin (PF-04971729, MK-8835) In Otherwise Healthy Overweight And Obese Volunteers (MK-8835-037)
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Ertugliflozin|DRUG: Placebo to Ertugliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Intracoronary Infusion of Bone Marrow Mononuclear Cells in Patients With Previous Myocardial Infarction.
Status: COMPLETED
Conditions: Chronic Myocardial Ischemia
Interventions: OTHER: Bone marrow mononuclear cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study That Evaluates the Effect of CYP3A4 Inhibition on Lu AG06466 in Healthy Men and Women
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lu AG06466|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: One-Piece Le Fort I Osteotomy Versus Segmental Le Fort I Osteotomy
Status: UNKNOWN
Conditions: Cleft Lip and Palate|Le Fort
Interventions: PROCEDURE: Segmental Le Fort I osteotomy|PROCEDURE: One-piece Le Fort I Osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Flutamide in Treating Women With Premenstrual Dysphoric Disorder
Status: COMPLETED
Conditions: Premenstrual Syndrome
Interventions: DRUG: Flutamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Skeletal Effects of Herbst and Invisalign MA in Growing Patients With KLass II Malocclusion
Status: RECRUITING
Conditions: Mandibular Growth Stimulation
Interventions: DEVICE: Stimulation of mandibular growth.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of I-gel to the Laryngeal Mask Airway
Status: COMPLETED
Conditions: Endotracheal Intubation|Supraglottic Airway
Interventions: DEVICE: i-gel airway (Intersurgical Ltd., Wokingham, England)|DEVICE: Laryngeal Mask Airway-Unique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of X0002 Spray in Subjects With Osteoarthritis of the Lumbar Spine
Status: WITHDRAWN
Conditions: Osteoarthritis of the Lumbar Spine|Pain, Back
Interventions: DRUG: X0002
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LED Photobiomodulation Therapy for Non-specific LBP in Working Nurses
Status: UNKNOWN
Conditions: Conditions for Lower Back Pain Working Nurse
Interventions: PROCEDURE: LED photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Female Urine, Vaginal & Endocervical Swab & Cervical Specimen Collections for APTIMA Trichomonas Vaginalis Assay Testing
Status: COMPLETED
Conditions: Trichomonas Vaginalis
Interventions: DEVICE: APTIMA Trichomonas vaginalis (ATV) Assay
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Organ Protection by Remote Ischemic Preconditioning for Surgical Treatment of Pediatric Congenital Heart Disease
Status: TERMINATED
Conditions: Heart Ischemia|Cerebral Ischemia
Interventions: OTHER: Remote ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of CKD-350
Status: UNKNOWN
Conditions: Dry Eye Syndrome
Interventions: DRUG: Xenobella|DRUG: Isotonic 0.3% Sodium Hyaluronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: (Macrolane VR30) in Buttocks Reshaping and contouringCellulite (Macrolane VR30) in Buttocks Reshaping and Contouring
Status: COMPLETED
Conditions: Cellulite of the Buttocks
Interventions: DEVICE: Hyaluronic acid injection (Macrolane VRF30)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Multicenter, Open-label, Safety and Preliminary Efficacy Study of the Surgical Implantation of OPKO's Glaucoma Drainage Device (AquashuntTM) in Patients With Refractory Chronic Forms of Open Angle Glaucoma (OAG)
Status: COMPLETED
Conditions: Glaucoma
Interventions: DEVICE: Aquashunt
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acupuncture on Insulin Sensitivity Polycystic Ovary Syndrome
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome|Insulin Resistance
Interventions: OTHER: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Tolerability of Two Topical Drug Products in the Treatment of Facial Acne
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Clindamycin and benzoyl peroxide gel (Duac® Topical Gel)|DRUG: benzoyl peroxide and adapalene gel (EPIDUO™ Gel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pegylated Liposomal Doxorubicin Versus Daunorubicin to Treat Acute Lymphoblastic Leukemia:
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: VDCLD regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Approach for VC Lateralization, With Prolene Suture Stabilized Over Prolene Mesh
Status: COMPLETED
Conditions: Paralysis of Vocal Cords or Larynx|Bilateral Vocal Cord Paralysis
Interventions: PROCEDURE: Novel technique of Vocal cord Laterlization with Prolene suture.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in End Stage Renal Disease (ESRD) Patients on Hemodialysis to Determine Non-inferiority of the Theranova Dialyzer Compared to the FX80 Dialyzer
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DEVICE: Theranova 400 Dialyzer|DEVICE: FX80 Dialyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Starting a Testosterone and Exercise Program After Hip Injury
Status: COMPLETED
Conditions: Hip Fracture|Frailty|Sarcopenia
Interventions: DRUG: Testosterone|DRUG: Placebo gel|BEHAVIORAL: Supervised exercise training|BEHAVIORAL: Home exercise program|BEHAVIORAL: Health Education Modules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of External CounterPulsation for Postoperative Coronary Artery Bypass Grafting Patients
Status: UNKNOWN
Conditions: Counterpulsation|Coronary Artery Bypass
Interventions: DEVICE: External Counterpulsation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pravastatin, Idarubicin, and Cytarabine in Treating Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: cytarabine|DRUG: idarubicin|DRUG: pravastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Prosthetic Femoropopliteal Bypass Versus Viabahn Endoprosthesis for Treatment of Symptomatic Femoral Artery Occlusive Disease
Status: COMPLETED
Conditions: Atherosclerosis|Lower Extremity Ischemia|Claudication|Rest Pain
Interventions: PROCEDURE: Femoral-popliteal Bypass|DEVICE: Angioplasty and stent placement with Viabahn covered stent-graft(W.L. Gore & Associates, Flagstff, Arizona) of superficial femoral artery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2b Study of ASLAN004 in Adults With Moderate-to-Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Placebo Comparator|BIOLOGICAL: ASLAN004|BIOLOGICAL: ASLAN004|BIOLOGICAL: ASLAN004|BIOLOGICAL: ASLAN004
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)
Status: RECRUITING
Conditions: Pain|Virtual Reality|Placebo|Temporomandibular Disorder
Interventions: DEVICE: RelieVRx|DEVICE: Sham-VR|OTHER: No-VR (natural history control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Observational Study Regarding the Necessity of Inclusion of Foot Arch State Together With the Angiosome Theory Within the Wound, Ischemia and Foot Infection Classification (WIfI) to Enhance the Predictability of Wound Healing and Decision Making
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Limb-Threatening Ischemia|Diabetic Foot|Vascular Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Does Fluid Replacement From Preoperative NPO Status Improve Postoperative Recovery
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Lactated Ringer|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Activity of MK-8504 in Anti-retroviral-naïve, Human Immunodeficiency Virus 1 (HIV-1) Infected Participants (MK-8504-002)
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: MK-8504
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Injectable Platelet-Rich Fibrin for the Treatment of Temporomandibular Joint Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: i-PRF|PROCEDURE: Arthrocentesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antireflux Mucosectomy (ARMS) for Treatment of Gastroesophageal Reflux
Status: RECRUITING
Conditions: Gastro Esophageal Reflux
Interventions: PROCEDURE: Antireflux Mucosectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In Situ Simulation Training in Transferring Critically Ill COVID-19 Patients
Status: COMPLETED
Conditions: Simulation of Physical Illness|COVID-19 Respiratory Infection
Interventions: PROCEDURE: Simulation Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Amniotic Membrane Injection Comparing Two Doses (1 mL and 2 mL Injection) and a Placebo (Sterile Saline) in the Treatment of Osteoarthritis of the Knee
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Acellular Amniotic Membrane Derived Allograft Injection (NuDYN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Famitinib Versus Sunitinib in the Treatment of Advanced Gastrointestinal Stromal Tumour Patients After Failure of Imatinib
Status: TERMINATED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Famitinib capsules|DRUG: Sunitinib Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Behavioral and Pharmacologic Treatment of Polydrug Abuse
Status: COMPLETED
Conditions: Opioid Dependence|Cocaine Abuse
Interventions: DRUG: Methadone|BEHAVIORAL: Contingency Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention Trial to Increase Meaning in Work and Reduce Burnout
Status: COMPLETED
Conditions: Burnout, Professional
Interventions: BEHAVIORAL: Small group meetings (COMPASS: COlleagues Meeting to Promote And Sustain Satisfaction)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intubation of Patients With an Unstable Cervical Spine Using the CMAC Device
Status: COMPLETED
Conditions: Laminectomy
Interventions: DEVICE: Fiberoptic bronchoscope|DEVICE: CMAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: The Impact of an Intervention Taught by Trained Teachers on Childhood BMI z Score
Status: COMPLETED
Conditions: Evidence of an Intervention on Childhood BMI z Score
Interventions: OTHER: Training teachers on healthier lifestyles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of POSTbiotics Supplementation on Microbiome in OBese Children: the POST-OB Study
Status: UNKNOWN
Conditions: Childhood Obesity
Interventions: DRUG: Vitamin D3|DRUG: Immunofos|OTHER: Promotion of physical activity|OTHER: Healthy food habits promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Human Clinical Trial Evaluating the Effect of MealShape™ on Blood Glucose Level Following Consumption of Standard Meal
Status: COMPLETED
Conditions: Postprandial Glycemia|Postprandial Insulinemia
Interventions: DIETARY_SUPPLEMENT: MealShape cinnamon extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Efficacy and Safety of Andrographolide Sulfonate in Patients With Acute Bronchitis
Status: UNKNOWN
Conditions: Acute Bronchitis
Interventions: DRUG: andrographolide sulfonate|DRUG: andrographolide sulfonate simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Gabapentin Extended Release (G-ER)in the Treatment of Vasomotor (Hot Flashes/Hot Flushes) Symptoms in Postmenopausal Women.
Status: COMPLETED
Conditions: Hot Flashes
Interventions: DRUG: Gabapentin Extended-Release (G-ER) 1200 mg|DRUG: Gabapentin Extended-Release (G-ER) 1800 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Durvalumab in Different Combinations With Pralatrexate, Romidepsin and Oral 5-Azacitidine for Lymphoma
Status: UNKNOWN
Conditions: Lymphoma, T-Cell
Interventions: DRUG: Durvalumab|DRUG: Pralatrexate|DRUG: Romidepsin|DRUG: 5-Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Description of Immunologic, Enzymatic and Metabolic Biomarkers Associated to the Severity of COVID-19 (SARS-CoV-2) and Its Resolution
Status: COMPLETED
Conditions: Covid19
Interventions: PROCEDURE: Blood collection at Day 8, Day 16, Day 24, Month 6 and Month 12 after first symptoms from SARS-CoV-2 infection.|PROCEDURE: Blood collection at 1st injection of vaccine against COVID-19, at at second injection of vaccine, at Month 1, Month 2, Month 6 and Month 12 after second injection of vaccine for volunteers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Weekly Docetaxel Versus Weekly Docetaxel/Gemcitabine in the Treatment of Non-Small Cell Lung Cancer in Elderly Patients
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Docetaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Assessment of Premature Ventricular Contractions Suppression in Cardiomyopathy(PAPS)
Status: UNKNOWN
Conditions: Ventricular Premature Beats, Contractions, or Systoles|Cardiomyopathies
Interventions: PROCEDURE: Radiofrequency ablation|DRUG: Amiodarone (Antiarrhythmic drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Seldinger Technique Versus Venous Cut-Down for Placement of Totally Implantable Venous Access Ports
Status: COMPLETED
Conditions: Catheters, Indwelling
Interventions: PROCEDURE: Seldinger technique or venous cut-down for port placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Psycho-traumatic Consequences of the COVID-19 Health Crisis Among Professionals in Emergency Services
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: OTHER: PTSD evaluation of emergency room staff 9 and 12 months after the end of second lockdown in France during COvid-19 pandemic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Immediate Effects of Mental Practice and Therapeutic Exercise in Mild Smokers
Status: ACTIVE_NOT_RECRUITING
Conditions: Smokers
Interventions: BEHAVIORAL: Theapeutic exercise plus action observation training|BEHAVIORAL: Therapeutic exercise plus sham observation training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Esophageal Dysmotility - Prospective Study Evaluating Methods for Esophageal Dilation
Status: TERMINATED
Conditions: Esophageal Dysmotility
Interventions: DEVICE: Dilation by Balloon|DEVICE: Dilation by Semi-rigid Savary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 5 Versus 10 Units of Insulin in Hyperkalemia Management
Status: RECRUITING
Conditions: Hyperkalemia|Potassium Imbalance|Electrolyte Imbalance|Electrolyte Disturbance
Interventions: DRUG: Insulin regular|DRUG: Dextrose 50|DRUG: salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Validation Study of a Computerized Movement Analysis of the Colonoscope in Simulated Colonoscopy
Status: COMPLETED
Conditions: Education
Interventions: OTHER: 3D-Colonoscopy Progression Score|OTHER: Endoscopy Training System|OTHER: 3D-Colonoscopy Retraction Score
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Combined Effects of omega3 Fatty Acids and Curcumin Supplementation on Inflammatory and Endothelial Factors in Migraine Patients
Status: UNKNOWN
Conditions: Migraine
Interventions: DIETARY_SUPPLEMENT: omega 3 fatty acid|DIETARY_SUPPLEMENT: curcumin|DIETARY_SUPPLEMENT: omega 3 fatty acid placebo|DIETARY_SUPPLEMENT: curcumin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study for Treatment of Moderate or Severe, Periodic, "Cyclic", Breast Pain
Status: UNKNOWN
Conditions: Fibrocystic Disease of Breast|Fibrocystic Changes of Breast|Fibrocystic Mastopathy|Pain
Interventions: DRUG: IoGen (molecular iodine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Physiological Effects of Nitrous Oxide on Anaesthesia
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: sevoflurane on air/O2|DRUG: sevoflurane in N2O/O2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Acute Appendicitis and Microbiota - Etiology of Appendicitis and Antibiotic Therapy Effects
Status: ENROLLING_BY_INVITATION
Conditions: Acute Appendicitis
Interventions: DRUG: Ertapenem followed by levofloxacin and metronidazole|DRUG: Moxifloxacin|PROCEDURE: Appendectomy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: 18F-Fluciclovine PET/CT in the Assessment of Pancreatic Transplants
Status: COMPLETED
Conditions: Pancreatitis, Graft|Pancreatic Transplant Post-Transplant Dysfunction Rejection
Interventions: DRUG: 18F-fluciclovine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of Safety and Immunogenicity of Intradermal Unadjuvanted Portion of Pandemrix® Via a Microneedle Device With Intramuscular Adjuvanted Pandemrix® as Reference
Status: UNKNOWN
Conditions: Healthy
Interventions: BIOLOGICAL: Pandemrix® (H1N1 pandemic influenza)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Folic Acid and Vitamin B12 Supplementation in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Folic acid|DIETARY_SUPPLEMENT: Vitamin B12|DRUG: Oral hypoglycemic agents [Metformin +/- Sulfonylurea]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Local Anesthesia in Emergency Inguinal Hernia Surgery
Status: UNKNOWN
Conditions: Anesthesia|Incarcerated Inguinal Hernia
Interventions: PROCEDURE: Local Anesthesia|PROCEDURE: General Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Trappa Ethanolamine Tablets Combined With Ciclosporin in the Treatment of Primary Treatment of Non-severe Aplastic Anemia
Status: RECRUITING
Conditions: Non-severe Aplastic Anemia
Interventions: DRUG: Trappa ethanolamine tablets ; ciclosporin|DRUG: Placebo ; ciclosporin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Oral Bioavailability of Telmisartan / Hydrochlorothiazide (HCTZ) Fixed Dose Combination (FDC) Compared With Its Monocomponents in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Hydrochlorothiazide|DRUG: Telmisartan|DRUG: Telmisartan/HCTZ FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Acute and Chronic Exercise on Immune Phenotype of Indolent Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia Patients
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma|Indolent Non-hodgkin Lymphoma
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Cardiopulmonary Exercise Testing|PROCEDURE: Dual X-ray Absorptiometry|OTHER: Electronic Health Record Review|OTHER: Exercise Intervention|PROCEDURE: Physical Examination|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|PROCEDURE: Spirometry|OTHER: Physical Performance Testing|OTHER: Best Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-Motor Features of Cervical Dystonia (CD)
Status: COMPLETED
Conditions: Cervical Dystonia|Movement Disorders|Focal Dystonia|Signs and Symptoms|Nervous System Diseases|Neurologic Manifestations|Neuromuscular Manifestations|Spasmodic Torticollis
Interventions: DIAGNOSTIC_TEST: Neurological Examination|DIAGNOSTIC_TEST: Assessment of Non-Motor Features
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Cognitive Remediation Approaches for Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Cognitive Remediation|BEHAVIORAL: Computer Games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Treatment for Alcohol-Dependent Individuals With PTSD
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Alcohol Abuse|Substance-Related Disorders
Interventions: BEHAVIORAL: Seeking Safety|DRUG: Sertraline|DRUG: Pill placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Ketones, Muscle Metabolism, and SGLT2 Inhibitors - Protocol 1
Status: RECRUITING
Conditions: Heart Failure|Type 2 Diabetes Mellitus
Interventions: DRUG: Beta-hydroxy-butyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of pCAR-19B in the Treatment of CD19-positive Relapsed/Refractory B-ALL in Children and Adolescents
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Relapsed Pediatric ALL|Refractory Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: pCAR-19B cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide and Rituximab in Subjects With Previously Untreated Indolent Non-Hodgkin's Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Hodgkin's Lymphoma
Interventions: DRUG: Rituximab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: House Dust Mite Treatment of Asthma. The MITRA Trial House Dust Mite Treatment of Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: ALK HDM AIT Placebo|DRUG: ALK HDM AIT 6 DU|DRUG: ALK HDM AIT 12 DU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Keratometric Change After XEN, Trabeculectomy and Tube Shunts
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Glaucoma, Angle-Closure|Glaucoma Secondary|Glaucoma Eye
Interventions: DIAGNOSTIC_TEST: Corneal topography: OPD-Scan|DIAGNOSTIC_TEST: Corneal topography: Pentacam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Remote Ischemic Preconditioning on Peripheral Blood Biomarkers in Healthy Adults (EMINENT)
Status: RECRUITING
Conditions: Ischemic Preconditioning
Interventions: DEVICE: Remote ischaemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Efficacy and Safety of Ultrasound Guided Lead Implantation for Sacral Neuromodulation (SNM) in Subjects With Overactive Bladder (OAB) With X-Ray Guided Technique
Status: UNKNOWN
Conditions: Refractory Overactive Bladder
Interventions: PROCEDURE: ultrasound|PROCEDURE: X-ray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Online Education to Improve the Management of Rotator Cuff Related Shoulder Pain
Status: COMPLETED
Conditions: Subacromial Pain Syndrome|Rotator Cuff Injuries
Interventions: OTHER: Rotator Cuff Related Shoulder Pain E-Learning Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: OcuStem Nutritional Supplement in Diabetic Patients With Mild to Moderate Non-proliferative Retinopathy
Status: UNKNOWN
Conditions: Diabetic Retinopathy
Interventions: DIETARY_SUPPLEMENT: OcuStem Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label, Single- and Multiple-Dose Pharmacokinetic Study of Diazoxide Choline
Status: WITHDRAWN
Conditions: Hypertriglyceridemia
Interventions: DRUG: Diazoxide choline|DRUG: Diazoxide choline high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Animal-Assisted Therapy in Adolescents With Eating Disorders
Status: UNKNOWN
Conditions: Eating Disorders in Adolescence|Eating Disorders|Anorexia Nervosa/Bulimia
Interventions: BEHAVIORAL: Dog-Assisted Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Panobinostat With Fludarabine and Cytarabine for Treatment of Children With Acute Myeloid Leukemia or Myelodysplastic Syndrome
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Panobinostat|DRUG: Fludarabine|DRUG: Cytarabine|DRUG: Intrathecal Triples|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Home Program and Telerehabilitation for the Treatment Process in Patients With Breast Cancer-Related Lymphedema
Status: COMPLETED
Conditions: Breast Cancer Related Lymphedema|Telerehabilitation
Interventions: OTHER: Manuel Lymphatic Drainage(MLD), Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Self-efficacy, Beliefs and Adherence- Pilot and Feasibility Trial of a Pharmacist-led Intervention
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: OTHER: Health literacy-psychosocial support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Non-Invasive and Non-Contact Intracranial Pressure Waveform Recording Using Dynamic Video Ophthalmoscopy
Status: RECRUITING
Conditions: Intracranial Pressure Increase
Interventions: DEVICE: Video ophthalmoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Resection vs no Resection of the Primary in Colorectal Cancer With Unresectable Metastases
Status: TERMINATED
Conditions: Colonic Cancer|Unresectable Metastasis Originating in Colonic Cancer
Interventions: PROCEDURE: Colonic resection|DRUG: Chemotherapy- scheme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Efficacy of Thyme Honey Mouth Rinse on Polypharmacy-induced Xerostomia
Status: NOT_YET_RECRUITING
Conditions: Xerostomia
Interventions: DRUG: Honey Mouthwash|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Spinal Fentanyl or Epidural Analgesia in the Early First Phase of Induced Labor
Status: COMPLETED
Conditions: Labor Pain|Induced; Birth
Interventions: DRUG: Fentanyl Citrate|DRUG: Lidocaine 1% Injectable Solution|DRUG: Fentanyl Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of ANTidepressant RESponse and Development Risk of Bipolar Disorder
Status: NOT_YET_RECRUITING
Conditions: Depression, Bipolar|Major Depressive Disorder|Bipolar Disorder
Interventions: OTHER: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Vaccine (H2NVAC) Before Surgery for the Treatment of HER2-Expressing Ductal Carcinoma In Situ
Status: RECRUITING
Conditions: Breast Ductal Carcinoma In Situ
Interventions: BIOLOGICAL: Granulocyte-Macrophage Colony-Stimulating Factor|BIOLOGICAL: Multi-epitope HER2 Peptide Vaccine H2NVAC|PROCEDURE: Therapeutic Conventional Surgery|PROCEDURE: Echocardiography|PROCEDURE: Biospecimen Collection|PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bolus Versus Continuous Remimazolam for Anesthetic Induction
Status: NOT_YET_RECRUITING
Conditions: Hypotension on Induction
Interventions: DRUG: Remimazolam bolus|DRUG: Remimazolam continuous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Efficacy and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain After Abdominal Hysterectomy
Status: COMPLETED
Conditions: Hysterectomy|Postoperative
Interventions: DRUG: Morphine|DRUG: CG5503 IR|DRUG: CG5503 IR|DRUG: CG5503 IR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Response With Adalimumab and Its Impact on Quality of Life and Other Comorbidity Factors in Patients With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain
Status: COMPLETED
Conditions: Acute Pain|Low Back Pain, Mechanical
Interventions: BEHAVIORAL: Supported-Self Management (SSM)|OTHER: Spinal Manipulation Therapy (SMT)|COMBINATION_PRODUCT: SMT + SSM|DRUG: Standard Medical Care (SMC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maternal Autoimmune Disease Research Alliance (MADRA) Registry
Status: RECRUITING
Conditions: Autoimmune Diseases|Pregnancy Related|Systemic Lupus Erythematosus|Cutaneous Lupus|Rheumatoid Arthritis|Sjogren's Syndrome|Scleroderma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Avelumab and Methotrexate in in Low-risk Gestational Trophoblastic Neoplasias as First Line Treatment
Status: RECRUITING
Conditions: Gestational Trophoblastic Neoplasias (GTN)
Interventions: DRUG: Avelumab Injection|DRUG: Methotrexate 1 GM Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Intraligamentary Piroxicam and Articaine
Status: UNKNOWN
Conditions: Pulpitis - Irreversible
Interventions: DRUG: Intra-ligamentary Piroxicam|DRUG: Intra-ligamentary Articaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Novel Treatment to Enhance Smoking Cessation Before Cancer Surgery
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Contingency Management (CM)|BEHAVIORAL: Standard of Care (SC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wound Additives in Primary Total Joint Athroplasty
Status: COMPLETED
Conditions: Arthroplasty, Replacement
Interventions: BIOLOGICAL: Platelet Rich Plasma|BIOLOGICAL: Cellerate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Bishop Score and Transvaginal Ultrasound for Preinduction Cervical Assessment in Multiparas
Status: COMPLETED
Conditions: Failed Induction of Labor
Interventions: OTHER: Assessment of cervical status
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Three Different Doses of Oral Cholecalciferol on 25-Hydroxyvitamin D Changes Among Epilepsy Patients With Hypovitaminosis D
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Pharmacokinetics (PK) of MEHD7945A in Participants With Locally Advanced or Metastatic Epithelial Tumors
Status: COMPLETED
Conditions: Epithelial Tumors, Malignant
Interventions: DRUG: MEHD7945A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Bone Marrow Transplantation Using Related Donors in Patients With Aplastic Anemia
Status: COMPLETED
Conditions: Aplastic Anemia
Interventions: DRUG: anti-thymocyte globulin|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: mesna|DRUG: methotrexate|DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Blue vs Red Light During Levulan Based Photodynamic Therapy in Patients With Basal Cell Nevus Syndrome
Status: COMPLETED
Conditions: Basal Cell Nevus Syndrome
Interventions: DRUG: Levulan|OTHER: Red Light PDT|OTHER: Blue Light PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Strategies Based on RT-PCR or Antigenic Test for the Screening of SARS-CoV-2 Infection (COVID-19).
Status: COMPLETED
Conditions: SARS-CoV Infection
Interventions: DIAGNOSTIC_TEST: saliva sample combined to an anterior nare self-swabbing (Self-samples)|DIAGNOSTIC_TEST: saliva sample (Self-sample)|OTHER: Survey of SARS-COV-19 knowledge|OTHER: Survey of acceptability of the different self-samples.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Collecting and Storing Blood, Bone Marrow, and Other Samples From Patients With Acute Leukemia, Chronic Leukemia, or Myelodysplastic Syndromes
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Leukemia|Chronic Leukemia|Myelodysplasia
Interventions: OTHER: biologic sample preservation procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pre-Operative Staging of Pancreatic Cancer Using Superparamagnetic Iron Oxide Magnetic Resonance Imaging (SPIO MRI)
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Superparamagnetic Iron Oxide Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC