pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Carboplatin and Etoposide With or Without Oblimersen Sodium in Treating Patients With Extensive Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Extensive Stage Small Cell Lung Cancer|Recurrent Small Cell Lung Cancer
Interventions: BIOLOGICAL: oblimersen sodium|DRUG: carboplatin|DRUG: etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of DBM Fasciatherapy for Patients Suffering From Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: Fasciatherapy|PROCEDURE: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Escalation Antifungal Prophylaxis for Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Fungal Infection
Interventions: DRUG: Escalating prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacological Interaction of Rifampicin on Clindamycin in Staphylococcic Osteoarticular Infections
Status: COMPLETED
Conditions: Staphylococcal Infections
Interventions: BIOLOGICAL: Clindamycin and rifampicin dosages
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GNT Induction Treatment in Locally Advanced NPC
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: gemcitabine,nimotuzumab, toripalimab|DRUG: gemcitabine, cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Feasibility of Point of Care Birth Testing in Eswatini
Status: COMPLETED
Conditions: HIV Infections|HIV/AIDS|Pediatric HIV Infection|Transmission, Perinatal Infection|Infant Morbidity|Neonatal Infection
Interventions: DIAGNOSTIC_TEST: Point-of-care birth test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase II Clinical Trial of Chemo-radiotherapy in Combination With INO-3112 in Patients With Locally Advanced Cervical Cancer
Status: WITHDRAWN
Conditions: Uterine Cervical Neoplasms
Interventions: BIOLOGICAL: INO-3112 vaccine|RADIATION: Radiotherapy (Extrernal beam radiotherapy + brachytherapy)|DRUG: Cisplatin chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Trial of Bevacizumab, Lenalidomide, Docetaxel, and Prednisone (ART-P) for Treatment of Metastatic Castrate-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: Bevacizumab|DRUG: Lenalidomide|DRUG: Docetaxel|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of S95011 in Primary Sjögren's Syndrome Patients
Status: COMPLETED
Conditions: Primary Sjögren's Syndrome
Interventions: DRUG: S95011 concentrate for solution for infusion|DRUG: Placebo concentrate for solution for infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Refining and Implementing Technology-Enhanced Family Navigation to Promote Early Access and Engagement With Mental Health Services for Youth With Autism
Status: ENROLLING_BY_INVITATION
Conditions: Autism Spectrum Disorder|Implementation Science|Mental Health|Behavioral Health
Interventions: BEHAVIORAL: ATTAIN NAV Technology-Enhanced Family Navigation Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Two Center Study to Determine Effect of G17DT on Plasma Gastrin Levels in Patients With Colorectal Cancer.
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: G17DT|BIOLOGICAL: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioelectrical Impedance in Monitoring Hyperhydration and Polyneuromyopathy in Critically Ill Patients
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Acute|Respiratory Insufficiency|Lung Ventilator|Hyperhydration|Hypoxemia|Chronic Obstructive Pulmonary Disease Exacerbation|Septic Shock
Interventions: DEVICE: Bioelectrical impedance vector analysis (BIVA)|DIAGNOSTIC_TEST: Blood and urine analysis|DIAGNOSTIC_TEST: cumulative water balance
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Total-Body Irradiation With or Without Fludarabine Phosphate Followed By Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia in Remission|Acute Myeloid Leukemia in Remission|Aggressive Non-Hodgkin Lymphoma|Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Diffuse Large B-Cell Lymphoma|Hematopoietic and Lymphoid Cell Neoplasm|Indolent Non-Hodgkin Lymphoma|Mantle Cell Lymphoma|Myelodysplastic/Myeloproliferative Neoplasm|Plasma Cell Myeloma|Refractory Chronic Lymphocytic Leukemia|Refractory Hodgkin Lymphoma|Waldenstrom Macroglobulinemia
Interventions: PROCEDURE: Total-Body Irradiation|DRUG: Fludarabine Phosphate|DRUG: Mycophenolate Mofetil|DRUG: Cyclosporine|PROCEDURE: Peripheral Blood Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Midvastus Versus Medial Parapatellar Approach for Minimally Invasive Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combined Stent Insertion and HIFU Ablation for Pancreatic Carcinoma With Biliary Obstruction
Status: COMPLETED
Conditions: Pancreatic Carcinoma|Biliary Obstruction
Interventions: DEVICE: biliary stent and high-intensity focused ultrasound ablation system|DEVICE: biliary stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypercapnia and Orthostatic Tolerance in Postural Orthostatic Tachycardia Syndrome
Status: RECRUITING
Conditions: Postural Tachycardia Syndrome|Orthostatic Intolerance
Interventions: OTHER: RespirAct™ system (Thornhill Research Inc., Toronto, Canada)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Dairy Fat and Inulin on Fasting Induced Adipose Factor (FIAF) Blood Concentrations
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Inulin|OTHER: Complete diet|OTHER: Whole milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of TMS on PTSD Biomarkers
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS)|PROCEDURE: Sham Transcranial Magnetic Stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Care Solution for Coronary Disease Follow up
Status: COMPLETED
Conditions: ST Segment Elevation Myocardial Infarction|Non-ST Segment Elevation Myocardial Infarction|Unstable Angina
Interventions: DEVICE: BAMA solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Headache in the Emergency Department (ED) - A Multi-Center Research Network to Optimize the ED Treatment of Migraines
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Dexamethasone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Low-Carbohydrate Diet Combined With Probiotics for Weight Loss in Male Obese Patients.
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Low-carbohydrate diet|DIETARY_SUPPLEMENT: Probiotic compound preparations|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Ruxolitinib (INCB018424) Administered Orally to Patients With Androgen Independent Metastatic Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomised Treatment of Acute Pancreatitis With Infliximab: Double-blind, Placebo-controlled, Multi-centre Trial (RAPID-I)
Status: RECRUITING
Conditions: Acute Pancreatitis
Interventions: DRUG: Infusion of 5 mg/kg Infliximab|DRUG: Infusion of 10 mg/kg Infliximab|OTHER: 0.9% Sodium Chloride (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability of Subcutaneous Injection in Adult Subjects Undergoing Abdominoplasty
Status: COMPLETED
Conditions: Abdominal Obesity
Interventions: DRUG: STP705
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Combination Therapy in Children With ADHD
Status: COMPLETED
Conditions: ADHD|Attention Deficit Hyperactivity Disorder|Attention Deficit Disorder With Hyperactivity|Mental Disorders Diagnosed in Childhood|Attention Deficit and Disruptive Behavior Disorders
Interventions: DRUG: Methylphenidate ER|DRUG: Cyproheptadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Three Different Sensory Interventions on Pain Level During Heel Blood Collection in Term Infant
Status: COMPLETED
Conditions: Infant|Pain
Interventions: BEHAVIORAL: Sensory Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing Two Group Therapy Treatments for Binge Eating Disorder
Status: COMPLETED
Conditions: Eating Disorders
Interventions: BEHAVIORAL: Group Psychotherapy-Negative Emotion Focus|BEHAVIORAL: Group Psychotherapy- Self-Esteem Focus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BYL719 and Letrozole in Post-Menopausal Patients With Hormone Receptor-Positive Metastatic Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Estrogen Receptor-positive Breast Cancer|HER2-negative Breast Cancer|Invasive Ductal Breast Carcinoma|Progesterone Receptor-positive Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: PI3K inhibitor BYL719|DRUG: letrozole|OTHER: laboratory biomarker analysis|OTHER: pharmacological studies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid-Free Pain Control Regimen Following Robotic Radical Prostatectomy
Status: RECRUITING
Conditions: Pain Management|Opioid Use|Prostate Cancer
Interventions: DRUG: Oxycodone|DRUG: Acetaminophen|DRUG: Ketamine|DRUG: Ketorolac|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CD123-Directed Autologous T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML)
Status: ACTIVE_NOT_RECRUITING
Conditions: AML/MDS|B-ALL|T-ALL|BPDCN
Interventions: DRUG: CD123-CAR T|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Mesna|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Comparing Effects of Thulium Laser en Bloc Resection and Electrical Transurethral Resection of the Non-muscle Invasive Bladder Cancer
Status: UNKNOWN
Conditions: Bladder Cancer
Interventions: PROCEDURE: Thulium Laser en Bloc Resection of bladder tumor|PROCEDURE: Electrical transurethral resection of bladder tumor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Safety Follow-up Study of Cysteamine Bitartrate Delayed-release Capsules (RP103)
Status: COMPLETED
Conditions: Cystinosis
Interventions: DRUG: Cysteamine Bitartrate Delayed-release Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Demonstrate the Benefit of a New Kind of Anti-cancer Treatment [PReferentially Expressed Antigen of MElanoma (PRAME) Immunotherapy] for Patients With Non-Small Cell Lung Cancer (NSCLC), After Removal of Their Tumor
Status: COMPLETED
Conditions: Lung Cancer, Non-Small Cell
Interventions: BIOLOGICAL: Recombinant PRAME protein combined with the AS15 Adjuvant System GSK2302032A|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prosthetic Components and Stability in Amputee Gait
Status: COMPLETED
Conditions: Diabetes Mellitus|Leg Injuries|Traumatic Amputation
Interventions: DEVICE: Transverse plane rotation adaptor pylon|DEVICE: Rigid pylon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: HaemoCerTM Application in Breast Cancer Surgery
Status: COMPLETED
Conditions: Breast Neoplasm Female|Mastectomy, Segmental
Interventions: OTHER: HaemoCer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety & Performance of the Centauri System for Patients With Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DEVICE: Pulsed Field Ablation (PFA) using the Centauri System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parenting Support Intervention for Families Coping With Metastatic or Locally Recurrent Solid Tumor Diagnosis
Status: RECRUITING
Conditions: Metastatic Malignant Solid Neoplasm|Recurrent Malignant Solid Neoplasm
Interventions: OTHER: Best Practice|OTHER: Educational Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Assessing Evaluation of the Interest of Serum S100B Protein Determination in the Management of Pediatric Mild Traumatic Brain Injury
Status: COMPLETED
Conditions: Craniocerebral Trauma|Pediatrics
Interventions: PROCEDURE: usual care|PROCEDURE: S100B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mogamulizumab and Pembrolizumab in Treating Patients With Relapsed or Refractory Diffuse Large B Cell Lymphoma
Status: COMPLETED
Conditions: Recurrent Diffuse Large B-Cell Lymphoma|Recurrent High Grade B-Cell Lymphoma|Recurrent Transformed B-Cell Non-Hodgkin Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory High Grade B-Cell Lymphoma|Refractory Transformed B-Cell Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: Mogamulizumab|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Evaluation of an Astrocytic Glutamate Transporter (EAAT2) PET Tracer in Dementia
Status: RECRUITING
Conditions: Alzheimer Disease|Frontotemporal Dementia|Dementia
Interventions: DRUG: [18F]RP-115 PET/MRI or PET/CT and MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pain Control for Anterior Cruciate Ligament Reconstruction Patients With Adductor Canal or Femoral Perineural Infusions
Status: COMPLETED
Conditions: Pain, Postoperative|Anterior Cruciate Ligament Injury
Interventions: PROCEDURE: Adductor Canal perineural catheter placement|PROCEDURE: Femoral Nerve perineural catheter placement|DEVICE: Nimbus pump (Infutronix)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Screening for Postoperative Vital Signs Abnormalities, and Particularly Hemodynamic Ones, by Continuous Monitoring Using the Biobeat Patch
Status: COMPLETED
Conditions: Surgery--Complications
Interventions: DEVICE: Biobeat patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: DMT310-003 Topical in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: DMT310|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Role of Latent Toxoplasmosis in Female Patients With Active Acne Vulgaris
Status: NOT_YET_RECRUITING
Conditions: Acne Vulgaris|Toxoplasmosis
Interventions: DIAGNOSTIC_TEST: Free testosterone levels and toxoplasma igG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect Pulsatile IV Insulin Therapy on the Quality of Life in Patients With Types 1 and 2 Diabetes
Status: TERMINATED
Conditions: Diabetes Mellitus
Interventions: PROCEDURE: Effects of Pulsatile IV insulin on Diabetic Quality of Life
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Test Predicting Adrenal Insufficiency in Volunteers Under Prednisone Treatment
Status: COMPLETED
Conditions: Adrenal Gland Hypofunction
Interventions: PROCEDURE: adrenal insufficiency testing|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Thalidomide fOr the Prevention of Restenosis After Coronary ArtERy Stent Implantation
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Thalidomide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Food (High Fat and Low Fat Breakfast) on the Pharmacokinetics of Regorafenib
Status: COMPLETED
Conditions: Dietary Fats|Pharmacokinetics
Interventions: DRUG: Regorafenib (Stivarga, BAY73-4506)|DRUG: Regorafenib (Stivarga, BAY73-4506)|DRUG: Regorafenib (Stivarga, BAY73-4506)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Hip Arthroscopy Pain Control Randomized Control Trial (RCT)
Status: COMPLETED
Conditions: Hip Pain Chronic|Anesthesia|Bupivacaine
Interventions: PROCEDURE: Fascial iliac regional soft tissue infiltration blockade|BEHAVIORAL: Pain Score Survey|BEHAVIORAL: Pill Count|DRUG: Bupivacaine|DRUG: Liposomal Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acne Scarring in Skin of Color: Laser vs Microneedling
Status: WITHDRAWN
Conditions: Acne Vulgaris|Scar
Interventions: DEVICE: Microneedling|DEVICE: Fractional non-ablative 1,540nm laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Latina Friends Motivating the Soul (ALMA)
Status: WITHDRAWN
Conditions: Stress|Depression|Anxiety
Interventions: BEHAVIORAL: Latina Friends Motivating the Soul (ALMA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Evaluate The Effect Of SAR153191 (REGN88) Added To Other RA Drugs In Patients With RA Who Are Not Responding To Or Intolerant Of Anti-TNF Therapy (SARIL-RA-TARGET)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Sarilumab|DRUG: placebo|DRUG: hydroxychloroquine|DRUG: methotrexate|DRUG: sulfasalazine|DRUG: leflunomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Capsular Stability With Two Different IOL Models in Patients With Pseudoexfoliation Syndrome: an Exploratory Study
Status: UNKNOWN
Conditions: Cataract
Interventions: DEVICE: ISERT 250 (HOYA, Japan): a standard IOL|DEVICE: AMO ZCB00 IOL (Abbott Medical Optics, United States): a standard IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: pEEG Monitoring Effect on Delirium, Ventilator Days, and PICS
Status: RECRUITING
Conditions: Critical Illness|Post Intensive Care Unit Syndrome|Post Intensive Care Syndrome|Mechanical Ventilation Complication|Delirium|Sedative-Related Disorders; Subsequent Encounter|Analgesia
Interventions: DEVICE: SedLine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Single Dose Radiotherapy (SDRT) With or Without Adjuvant Systemic Therapy for Oligometastatic Prostate Cancer
Status: UNKNOWN
Conditions: Metastatic Prostate Cancer|Prostate Adenocarcinoma
Interventions: RADIATION: Single Dose Radiotherapy (24 Gy) to all detectable lesions, followed by observation|DRUG: Single Dose Radiotherapy (24 Gy) to all detectable lesions followed by adjuvant systemic therapy for 6 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term, Open-label, Safety Study of Inebilizumab in Neuromyelitis Optica Spectrum Disorder (NMOSD)
Status: RECRUITING
Conditions: Neuromyelitis Optica Spectrum Disorder
Interventions: OTHER: Blood tests|DRUG: Inebilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EMBRace With Grandparents
Status: COMPLETED
Conditions: Racial Discrimination|Depression|Anxiety|Stress|Trauma, Psychological
Interventions: BEHAVIORAL: EMBRace Intervention Group|BEHAVIORAL: EMBRace Waitlist Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Distance and Intermediate Visual Acuity in Patients With Implanted Monofocal Negative Aspheric Intraocular Lens
Status: RECRUITING
Conditions: Intraocular Lens
Interventions: DEVICE: Monofocal intraocular lens Clareon (Alcon LLC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Treatments for Barrett's Esophagus With High-Grade Dysplasia/Early Adenocarcinoma
Status: COMPLETED
Conditions: Barrett's Esophagus
Interventions: DEVICE: Radio-Frequency Ablation|DEVICE: Cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Reverse Shoulder Data Collection
Status: ENROLLING_BY_INVITATION
Conditions: Arthropathy of Shoulder Region|Grossly Deficient Rotator Cuff|Osteoarthritis of the Shoulder|Rheumatoid Arthritis Without Humeral Metaphyseal Defects|Post-Traumatic Arthitis
Interventions: DEVICE: Biomet Comprehensive Reverse Shoulder
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating the Efficacy and Safety of Desvenlafaxine Tablets in Adult Outpatients With Major Depressive Disorder
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: desvenlafaxine 50 mg|DRUG: desvenlafaxine 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Immunotherapy With Autologous HIV-Specific CD8 Cells in HIV Infected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: PROCEDURE: Adoptive transfer of HIV-specific CD8+ T cells|DRUG: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gefitinib in Combination With Anlotinib or Placebo in Previously Untreated EGFR-mutant NSCLC
Status: UNKNOWN
Conditions: Lung Cancer, Nonsmall Cell
Interventions: DRUG: Gefitinib|DRUG: Anlotinib Hydrochloride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self-control Trial to Evaluate the Role of Aprepitant in the Prophylaxis of Post-lumbar-punture-headache (PLPH)
Status: UNKNOWN
Conditions: Leukemia|Lymphoma
Interventions: DRUG: Aprepitant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment With Recombinant Human Growth Hormone Genotonorm (Registered) In Children With Short Stature Secondary
Status: COMPLETED
Conditions: Growth Hormone Deficiency|Growth Retardation
Interventions: DRUG: Somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Effects of Nevirapine (VIRAMUNE®) on the Steady State Pharmacokinetics of Rifabutin (MYCOBUTIN®) in HIV+ Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nevirapine|DRUG: Rifabutin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Observe the Capability to Absorb Calcium as an Measure of Adequate Levels of Vitamin D
Status: COMPLETED
Conditions: Postmenopausal|Vitamin D Deficiency
Interventions: OTHER: Dual isotope technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Aliskiren and Valsartan Versus Placebo in Patients Stabilized Following an Acute Coronary Syndrome
Status: COMPLETED
Conditions: Post Acute Coronary Syndrome|Myocardial Ischemia
Interventions: DRUG: Placebo|DRUG: Aliskiren 300 mg|DRUG: Valsartan 320 mg|DRUG: Aliskiren/valsartan 300/320 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Psilocybin's Effect on Cardiac Repolarization and the Effect of Food on Psilocybin's Pharmacokinetics
Status: COMPLETED
Conditions: QTc Interval|Pharmacokinetics
Interventions: DRUG: Psilocybin|DRUG: Moxifloxacin|DRUG: Micro-Crystalline Cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing the Safety and Efficacy of Intravenous CXA-201 and Intravenous Meropenem in Complicated Intraabdominal Infections
Status: COMPLETED
Conditions: Complicated Intra-abdominal Infection
Interventions: DRUG: CXA-201 and metronidazole|DRUG: Meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ENRICH: Early MiNimally-invasive Removal of IntraCerebral Hemorrhage (ICH)
Status: COMPLETED
Conditions: Intracerebral Hemorrhage|Cerebral Hemorrhage|Intracerebral Haemorrhage
Interventions: PROCEDURE: Early Surgical Hematoma Evacuation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Health Insurance Experiences for Adolescent and Young Adult Cancer Patients
Status: COMPLETED
Conditions: Adolescent|Young Adult|Cancer
Interventions: BEHAVIORAL: Health Insurance Education Program (HIEP)|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Uterotonic Efficacy of Oxytocin 2.5 Versus 10 Units During Caesarean Section at Mulago Hospital
Status: COMPLETED
Conditions: Adverse Effect of Oxytocic Drugs|Uterine Hemorrhage|Inappropriate Dose of Drug Administered
Interventions: DRUG: 2.5 units Oxytocin|DRUG: 10 units Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Ketorolac Vs. Morphine In Children With Acute Abdominal Pain
Status: RECRUITING
Conditions: Acute Pain|Abdomen, Acute|Abdominal Pain|Appendicitis|Emergencies|Child, Only
Interventions: DRUG: Ketorolac Tromethamine|DRUG: Morphine Sulfate|DRUG: normal saline|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fitbit Pilot Study in Post-operative Lumbar Degenerative Spinal Stenosis Patients
Status: UNKNOWN
Conditions: Lumbar Degenerative Spinal Stenosis
Interventions: BEHAVIORAL: Blinded Fitbit|BEHAVIORAL: Fitbit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Persistent PostConcussion-Like Symptoms and Post Traumatic Stress Disorder in Patients Presenting at the Emergency Room.
Status: COMPLETED
Conditions: Persistent PostConcussion-Like Symptoms|Post-Traumatic Stress Disorder
Interventions: OTHER: R-TEP EMDR intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Aerosolized Antibiotics and Respiratory Tract Infection in Patients on Mechanical Ventilation
Status: COMPLETED
Conditions: Ventilator Associated Pneumonia|Respiratory Infection|Tracheobronchitis
Interventions: DRUG: aerosolized vancomycin or gentamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Transversus Abdominis Plane Block With Ropivacaine vs Placebo for Abdominal Hysterectomy: a Double-blinded, Randomized Clinical Trial
Status: COMPLETED
Conditions: Postoperative Pain and Postoperative Morphine Consumption After Abdominal Hysterectomy
Interventions: PROCEDURE: TAP Block Ropivacaine 0,75 %|PROCEDURE: TAP Block Saline 0,9 %
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic/Pharmacodynamic (PK/PD) Study Evaluating Pegfilgrastim Hospira Compared to Neulasta (Amgen) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pegfilgrastim Hospira|DRUG: Neulasta (Amgen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Multisite Controlled Trial of Cocaine Vaccine
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: TA-CD Vaccination|OTHER: Placebo Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The GOS-Frail (Geriatric Oncology Supportive Care for Frail Older Adults With Cancer) Study
Status: NOT_YET_RECRUITING
Conditions: Geriatric Oncology|Supportive Care|Quality of Life
Interventions: OTHER: Geriatric Oncology Supportive Clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant Dalpiciclib Plus Aromatase Inhibitors in Luminal B/HER2-negative Breast Cancer (DANCER)
Status: RECRUITING
Conditions: Luminal B/HER2-negative Breast Cancer
Interventions: DRUG: Dalpiciclib combined with aromatase inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Asthma Treatment Using Inhaler Technology
Status: UNKNOWN
Conditions: Asthma
Interventions: BEHAVIORAL: Active feedback on monitored inhaler use|DEVICE: Inhaler casing|DEVICE: Mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sirolimus and Cyclosporine for Treatment-Resistant Aplastic Anemia
Status: UNKNOWN
Conditions: Anemia, Aplastic
Interventions: DRUG: Sirolimus|DRUG: Cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Compare BCG-Bulgaria and BCG-Denmark
Status: RECRUITING
Conditions: Death; Neonatal|Death, Infant|Morbidity;Newborn|Morbidity;Infant|Non-specific Effects of Vaccines
Interventions: BIOLOGICAL: BCG-Denmark|BIOLOGICAL: BCG-Bulgaria
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Continuous TQL Block for Elective Cesarean Section
Status: COMPLETED
Conditions: Postoperative Pain|Anesthesia, Local
Interventions: DRUG: Ropivacaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Study of the Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic Profile of VX-984 in Combination With Chemotherapy
Status: COMPLETED
Conditions: Advanced Solid Tumor
Interventions: DRUG: VX-984 120 mg + PLD 40 mg/m^2|DRUG: VX-984 240 mg + PLD 40 mg/m^2|DRUG: VX-984 480 mg + PLD 40 mg/m^2|DRUG: VX-984 720 mg + PLD 40 mg/m^2
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Kaffes Stent With Plastic Prosthesis in the Treatment of Anastomotic Biliary Strictures Post Orthotopic Liver Transplantation
Status: COMPLETED
Conditions: Biliary Strictures Post Liver Transplantation
Interventions: PROCEDURE: Plastic stenting|PROCEDURE: Kaffes stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Measles, Mumps, and Rubella Investigational Vaccine Trial (V205C-010)(COMPLETED)
Status: COMPLETED
Conditions: Measles
Interventions: BIOLOGICAL: V205C, measles, mumps, and rubella virus vaccine live|BIOLOGICAL: Comparator: Measles, Mumps, and Rubella Virus Vaccine Live
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A RCT of the Efficacy of Tegoprazan 50mg QD in the Treatment of Helicobacter Pylori Infection ( TATH-1 )
Status: ACTIVE_NOT_RECRUITING
Conditions: Vonoprazan|Helicobacter Pylori Infection|Proton Pump Inhibitor
Interventions: DRUG: Tegoprazan|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Graft Function After Treatment With Erythropoietin (EPO)
Status: TERMINATED
Conditions: Ischemia
Interventions: DRUG: beta-epoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Glycopyrrolate on Heart Rate and Heart Rate Variability in Patients With Different Basic Heart Rate
Status: COMPLETED
Conditions: Glycopyrrolate
Interventions: DRUG: Glycopyrrolate|DRUG: Glycopyrrolate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparative Study of ZG-801 and Placebo in Patients With Hyperkalemia
Status: COMPLETED
Conditions: Hyperkalemia
Interventions: DRUG: Calcium, hydrolysed divinylbenzene-Me 2-fluoro-2-propenoate-1, 7-octadiene polymer sorbitol complexes|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The PK/PD Study of SHR0532 Tablets in Healthy Subjects
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: SHR0532|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GI Reflux in Lung Transplant and Its Relationship to Chronic Rejection
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: PROCEDURE: esophagogastroduodenoscopy|OTHER: Standard GER questionnaire (RDQ)|PROCEDURE: Scintigraphic evaluation of solid gastric emptying|PROCEDURE: Twenty-four hour ambulatory pH testing|PROCEDURE: Esophageal manometry testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Postoperative Adjuvant Treatments for Hepatocellular Carcinoma With Portal Vein Tumor Thrombosis
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: OTHER: PVIC, TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Estimate the Effect of Formulation on the Relative Absorption of SB-751689 Administered to Healthy Women
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: SB-751689 oral tablets (400 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Sorafenib to Treat Advanced Medullary Thyroid Carcinoma
Status: WITHDRAWN
Conditions: Medullary Thyroid Carcinoma
Interventions: DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Talimogene Laherparepvec (T-VEC) in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcoma|Epithelioid Sarcoma|Cutaneous Angiosarcoma
Interventions: DRUG: Talimogene Laherparepvec (T-VEC)|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Titration of PEEP During Mechanical Ventilation in Patients With ARDS Using Electrical Impedance Tomography.
Status: WITHDRAWN
Conditions: Acute Respiratory Distress Syndrome
Interventions: DEVICE: Electrical Impedance Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TAS-120 in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Cholangiocarcinoma|Urothelial Cancer|Advanced and Metastatic Cancer Patients With Tumors Harboring FGF/FGFR Tumors|Primary CNS Tumors|Breast Cancer|Gastric Cancer
Interventions: DRUG: Futibatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mifepristone (RU-486) in Androgen Independent Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Adenocarcinoma of Prostate
Interventions: DRUG: Mifepristone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate The Efficacy Of Tofacitinib In Patients With SJS/TEN
Status: RECRUITING
Conditions: Stevens-Johnson Syndrome|Toxic Epidermal Necrolysis
Interventions: DRUG: Tofacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Clinical Trial Comparing the Efficacy of RO7198457 Versus Watchful Waiting in Patients With ctDNA-positive, Resected Stage II (High Risk) and Stage III Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer Stage II|Colorectal Cancer Stage III
Interventions: DRUG: RO7198457 intravenous (IV)|OTHER: Observational group (no intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Donor Natural Killer Cells Given After Haploidentical Hematopoietic Cell Transplantation
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: donor natural killer cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effects Icodextrin Versus Dianeal on Insulin Resistance in Nondiabetic Automated Peritoneal Dialysis Patients
Status: COMPLETED
Conditions: Disorders Associated With Peritoneal Dialysis
Interventions: OTHER: icodextrin|OTHER: Dianeal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ozurdex for Combined Pseudophakic Cystoid Macular Edema and Diabetic Macular Edema After Cataract Surgery
Status: COMPLETED
Conditions: Pseudophakic Cystoid Macular Edema,|Diabetic Macular Edema
Interventions: DRUG: Dexamethasone Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy Study in Progressive or Relapsed Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer|Progression of Non-small Cell Lung Cancer|Non-small Cell Lung Cancer Recurrent
Interventions: DRUG: Docetaxel|BIOLOGICAL: HyperAcute®-Lung Immunotherapy|DRUG: Gemcitabine|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Patients Receiving a Unicompartmental Knee Replacement With Robotic Assistance or With Conventional Instrumentation
Status: WITHDRAWN
Conditions: Arthritis|Osteoarthritis|Knee|Joint Diseases|Musculoskeletal Diseases|Rheumatic Diseases
Interventions: DEVICE: NAVIO/CORI Surgical System|PROCEDURE: Non-robotic conventional instrumentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Dose-Dense For Early Her2Neu Positive Breast Cancer
Status: TERMINATED
Conditions: Locally Advanced Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: Carboplatin|DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Pegfilgrastim|DRUG: Trastuzumab|DRUG: Paclitaxel|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Focal US-guided Cryo-ablation Using DynaCAD / UroNAV Preplanning / Guidance of Intermediate Risk Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Prostate Disease
Interventions: DEVICE: Cryo-ablation Using DynaCAD / UroNAV preplanning / guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Reductions in Intersectional StigMa (PRISM) - GHANA
Status: COMPLETED
Conditions: HIV|Stigma
Interventions: BEHAVIORAL: Health Policy Plus (HP+)|BEHAVIORAL: Many Men Many Voices (3MV)|BEHAVIORAL: HIV Education, Empathy and Empowerment (HIVE3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study To Assess FRacTure Healing With SclerosTin Antibody - Hip
Status: COMPLETED
Conditions: Fracture Healing
Interventions: DRUG: Placebo|DRUG: Romosozumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Trial of MK-4334 in Participants With Alzheimer's Clinical Syndrome (MK-4334-005)
Status: UNKNOWN
Conditions: Alzheimer's Disease|Mild Cognitive Impairment
Interventions: DRUG: MK-4334|DRUG: Placebo to MK-4334|DRUG: Donepepzil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shared Decision Making in Surveillance for Distant Metastasis in Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Survivorship|Quality of Life
Interventions: DIAGNOSTIC_TEST: Shared decision making|DIAGNOSTIC_TEST: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING