pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Use of Allograft Cartilage in Cosmetic and Reconstructive Rhinoplasty
Status: COMPLETED
Conditions: Rhinoplasty
Interventions: OTHER: Autologous Costal Cartilage Graft|OTHER: Costal Cartilage Allograft.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AKITA Inhaled Steroid Suspension for Inhalation (AICS) in Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide|DRUG: Budesonide|DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Effects of Omega-3 Fatty Acid Supplementation in Acne Patients
Status: TERMINATED
Conditions: Acne
Interventions: DIETARY_SUPPLEMENT: Omega-3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Manipulating the Microbiome in IBD by Antibiotics and FMT
Status: COMPLETED
Conditions: Exacerbation of Ulcerative Colitis|Ulcerative Colitis, Active Severe|Crohn's Colitis
Interventions: DRUG: AB (antibiotics)|DRUG: CS (corticosteroids) Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ramelteon Combined With Gabapentin in Treating Patients With Insomnia
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: DRUG: Ramelteon and gabapentin|DRUG: Ramelteon and gabapentin|DRUG: Ramelteon|DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effecttiveness of Intratympanic Methylprednisolon Injections Compared to Placebo in the Treatment of Vertigo Attacks in Meniere's Disease
Status: RECRUITING
Conditions: Meniere Disease
Interventions: DRUG: Methylprednisolon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Nivolumab-relatlimab Fixed-dose Combination Versus Regorafenib or TAS-102 in Participants With Later-lines of Metastatic Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Neoplasms
Interventions: DRUG: Nivolumab-relatlimab FDC|DRUG: Regorafenib|DRUG: TAS-102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Verapamil in Chronic Rhinosinusitis
Status: TERMINATED
Conditions: Sinusitis|Nasal Polyps
Interventions: DRUG: Verapamil HCl|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Veterans Affairs Pharmacist Heart Failure Medication Titration Project 1
Status: ENROLLING_BY_INVITATION
Conditions: Heart Failure
Interventions: OTHER: Audit and Feedback Emails|OTHER: Patient Specific Targets|OTHER: Educational Resources
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dietary and Dialysate Sodium Reduction on Body Fluid Volume and Inflammatory State in Hemodialysis Patients
Status: COMPLETED
Conditions: Chronic Kidney Diseases Stage 5
Interventions: OTHER: Dietary sodium restriction|OTHER: Dialysate sodium concentration reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Veteran Support for Smoking Cessation Pilot Project (VAntage Pilot)
Status: RECRUITING
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Support Person Coaching Intervention|BEHAVIORAL: Support Person Written Materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Batiraxcept (AVB-S6-500)/Placebo in Combination With Paclitaxel in Patients With Platinum-Resistant Recurrent Ovarian Cancer
Status: TERMINATED
Conditions: Platinum-resistant Ovarian Cancer
Interventions: DRUG: Batiraxcept|DRUG: Paclitaxel|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Alfentanil and the Elimination of Sympathetic Responses to Tracheal Intubation During Rapid Sequence Induction of Anesthesia: A Probability-based Approach
Status: COMPLETED
Conditions: Anesthesia Intubation Complication
Interventions: DRUG: Alfentanil 0.5mg/ml (Rapifen , Janssen-Cilag)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Test GlaxoSmithKline's (GSK) Candidate Vaccine-GSK1437173A for Prevention of Shingles in Children With Kidney Transplant
Status: RECRUITING
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: PED-HZ/su
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CBCR for Executive Functions in Patients With ABI in the Chronic Phase
Status: COMPLETED
Conditions: Acquired Brain Injury|Cognitive Symptom|Executive Dysfunction
Interventions: BEHAVIORAL: Computer based cognitive rehabilitation|OTHER: Sham computerized gaming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Famotidine & N-Acetyl Cysteine for Outpatients With COVID-19
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: Famotidine|DRUG: N-Acetyl cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Blood Based Biomarkers for Pancreas Adenocarcinoma
Status: RECRUITING
Conditions: Pancreatic Cancer|Pancreatic Diseases|Pancreatitis|Pancreatic Cyst
Interventions: DIAGNOSTIC_TEST: Blood Draw|DIAGNOSTIC_TEST: Tumor Tissue Collection|DIAGNOSTIC_TEST: Cyst Fluid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Heart Failure Diuresis Efficacy Comparison (DEA-HF) Study
Status: COMPLETED
Conditions: Chronic Heart Failure|Diuretics Drug Reactions|Congestive Heart Failure
Interventions: DRUG: IV Furosemide|DRUG: IV Furosemide and PO Metolazone|DRUG: IV Furosemide and IV Acetazolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Adalimumab in Refractory Diabetic Retinopathy, Choroidal Neovascularization or Uveitis: A Pilot Study
Status: UNKNOWN
Conditions: Uveitis|Diabetic Retinopathy|Choroidal Neovascularization
Interventions: DRUG: adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Whole-body Vibration Therapy on Type 2 Diabetic Patients With and Without Polyneuropathy
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes|Diabetic Peripheral Neuropathy|Exercise
Interventions: OTHER: exercise with whole body vibration device|OTHER: placebo exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Measure the Effect of Two Fluoride Toothpastes on Gingival Health Over a Six Month Period
Status: COMPLETED
Conditions: Gingival Diseases
Interventions: OTHER: Fluoride Toothpaste 1|OTHER: Fluoride Toothpaste 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Double-Blind Study of Placebo vs. Ketamine For Use During Dressing Changes in Critically Ill Burn Patients
Status: WITHDRAWN
Conditions: Thermal Hyperalgesia|Anxiety|Pain
Interventions: DRUG: Ketamine|DRUG: Placebo, Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Submucosal Intravesical Injection of Platelet-rich Plasma in the Treatment of Painful Bladder Syndrome
Status: COMPLETED
Conditions: Painful Bladder Syndrome (PBS)|Interstitial Cystitis
Interventions: DRUG: Intravesical injection of Platlet Rich Plasma (PRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Body-mapping Tank Top Equipped With Biofeedback System for Adolescent With Early Scoliosis
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: DEVICE: Body-mapping Tank-top Embedded with Biofeedback System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immuno-persistence Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls (54m)
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Intraepithelial Neoplasia|Cervical Cancer|Vaginal Intraepithelial Neoplasia|Vulvar Intraepithelial Neoplasia|Persistent Infection
Interventions: DRUG: Recombinant Human Papillomavirus Bivalent (Types 16, 18) Vaccine (Escherichia coli)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: INFUSE®Bone Graft in Transforaminal Lumbar Interbody Fusion for Degenerative Disease of Lumbosacral Spine
Status: TERMINATED
Conditions: Lumbar Spine Degeneration
Interventions: DEVICE: INFUSE Bone Graft|OTHER: Iliac Crest Bone Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cap Assisted Forward-Viewing Endoscope vs Side-Viewing Endoscope for Examination of Major Duodenal Papilla
Status: COMPLETED
Conditions: Duodenal Papilla, Major
Interventions: PROCEDURE: cap assisted forward-viewing endoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Helicobacter Pylori Eradication on Liver Fat Content in Non-alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Fatty Liver|Liver Dysfunction|Insulin Resistance
Interventions: DRUG: H.pylori eradication (Omeprazole, Amoxicillin, Bismuth subcitrate, Azithromycin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of Intravenous Sulopenem And Oral PF-03709270 In Community Acquired Pneumonia That Requires Hospitalization
Status: COMPLETED
Conditions: Pneumonia, Bacterial
Interventions: DRUG: sulopenem and PF-03709270|DRUG: Sulopenem and PF-03709270|DRUG: Ceftriaxone and amoxicillin/clavulanate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medically Tailored Groceries and Food Resource Coaching
Status: RECRUITING
Conditions: Nutrition, Healthy|Type 2 Diabetes|Hypertension|Dyslipidemias
Interventions: BEHAVIORAL: Medically tailored groceries and food resource coaching|OTHER: Free community food support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Characterization and Treatment of Chemotherapy Neuropathy
Status: COMPLETED
Conditions: Chemotherapy-induced Neuropathy
Interventions: PROCEDURE: Photon stimulation|PROCEDURE: Placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: POEM (Practice Of Embracing Each Moment) STUDY
Status: COMPLETED
Conditions: Distress|Cancer|Chemotherapy Effect
Interventions: BEHAVIORAL: Mindfulness meditation program (administered via mobile app)|BEHAVIORAL: Progressive muscle relaxation (via mobile app)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment (ASCEND)
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome|Extracorporeal Membrane Oxygenation
Interventions: DEVICE: ECMO support|OTHER: PROSpect protocolized therapies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Overfeeding and Following Exercise Training in Individuals With and Without Increased Risk of Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Insulin Resistance|Dyslipidemia
Interventions: DIETARY_SUPPLEMENT: High carbohydrate overfeeding|BEHAVIORAL: Exercise|BEHAVIORAL: Normal physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Palonosetron, Ondansetron, and Dexamethasone for Delayed Nausea and Vomiting in Autologous Transplant Patients
Status: COMPLETED
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Palonosetron|DRUG: ondansetron|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Perfluorocarbon Perfused Vitrectomy and 3D Vitrectomy System in Advanced Diabetic Retinopathy
Status: WITHDRAWN
Conditions: Diabetic Retinopathy
Interventions: PROCEDURE: Vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double Blinded Study to Examine the Effect of Coated Suppositories on Fecal Incontinence in Patients With Spinal Cord Injury
Status: WITHDRAWN
Conditions: Fecal Incontinenece
Interventions: DRUG: caoted suppository|DRUG: coated suppository
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemia Precondition (RIPC) for Hepatic Protection in Patients Undergoing Hepatectomy
Status: UNKNOWN
Conditions: Liver Neoplasms
Interventions: OTHER: Remote ischemia precondition|OTHER: None remote ischemia precondition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Esophagitis
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: OTHER: Placebo|DRUG: lirentelimab (AK002)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab in Combination With Chemotherapy as a Neoadjuvant Treatment for Advanced Endometrial Cancer
Status: NOT_YET_RECRUITING
Conditions: Endometrial Neoplasms
Interventions: DRUG: Tislelizumab|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy, & Pharmacokinetic Study of Tamibarotene to Treat Patients With Relapsed or Refractory APL
Status: COMPLETED
Conditions: Acute Promyelocytic Leukemia
Interventions: DRUG: Tamibarotene
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of Tocilizumab in Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Methotrexate|DRUG: tocilizumab [RoActemra/Actemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Pharmacokinetic Characteristics of DW5221 and DW5221-R
Status: COMPLETED
Conditions: Apetite Stimulants
Interventions: DRUG: DW5221|DRUG: DW5221-R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bupivacaine Infiltration and Postoperative Pain
Status: UNKNOWN
Conditions: Postoperative Pain|Local Infiltration|Analgesia
Interventions: DRUG: Bupivacain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acetaminophen and Ascorbate in Sepsis: Targeted Therapy to Enhance Recovery
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Critical Illness|Respiratory Failure|Sepsis
Interventions: DRUG: Intravenous Acetaminophen (room temperature)|DRUG: Intravenous Vitamin C (refrigerated)|DRUG: 5% Dextrose (room temperature)|DRUG: 5% Dextrose refrigerated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose Study in Subjects With Severe Hemophilia A Comparing Pharmacokinetic Parameters for BAY81-8973 and Advate
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: BAY81-8973|DRUG: Advate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating the Effects of Tasimelteon vs Placebo on Sleep Disturbances in SMS
Status: COMPLETED
Conditions: Smith-Magenis Syndrome|Circadian
Interventions: DRUG: tasimelteon|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Handgrip Exercise for Arteriovenous Fistula Maturation
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: OTHER: Post operative progressive handgrip exercise|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Evaluation of Cow's Milk Formula - Study B
Status: COMPLETED
Conditions: Healthy Term Infants
Interventions: OTHER: Infant formula|OTHER: Infant formula|OTHER: Cow's milk infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Assisted Movement Neuro-rehabilitation: VA Multi-site Clinical Trial
Status: COMPLETED
Conditions: Cerebrovascular Disorders|Hemiplegia
Interventions: OTHER: Robot-Low|OTHER: Robot-High|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy, Surgery, and Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Pharmacokinetics (PK) of Single Subcutaneous (SC) Injections of Vedolizumab Administered in Prefilled Syringe (PFS) Versus (vs) Prefilled Syringe in Autoinjector (PFS+AI) in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Vedolizumab SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Daily vs Intermittent Restriction of Energy: Controlled Trial to Reduce Diabetes Risk (DIRECT)
Status: COMPLETED
Conditions: Individuals at Risk of Developing Diabetes
Interventions: OTHER: Intermittent Fasting (IF)|OTHER: Daily Restriction (DR)|OTHER: standard care (SC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Conversion Pharmacodynamic Study in Stable Renal Transplant Patients Receiving Tacrolimus Two Times a Day to a New Formulation of Tacrolimus - LCP Tacro - 1 Time a Day.
Status: COMPLETED
Conditions: Kidney Transplant; Complications
Interventions: DRUG: Drug conversion from Tacrolimus (Prograf® or Adoport®) to LCP-Tacrolimus (Envarsus®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid Treatment of PTSD With Accelerated Non-Invasive Brain Stimulation
Status: NOT_YET_RECRUITING
Conditions: Post Traumatic Stress Disorder|Traumatic Brain Injury
Interventions: DEVICE: Cool B70 AP Coil - Active (dl-PFC)|DEVICE: Cool B70 AP Coil- Sham (dl-PFC)|DEVICE: Cool D-B80 AP Coil - Active (dm-PFC)|DEVICE: Cool D-B80 AP Coil - Sham (dm-PFC)|DEVICE: Cool B70 Treatment Coil - Active Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of HUEXC030 in Subjects With Pulmonary Tuberculosis
Status: COMPLETED
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: Isoniazid with HUEXC030 and RZE|DRUG: HRZE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Autologous Osteoblastic Cells Implantation to Early Stage Osteonecrosis of the Femoral Head
Status: TERMINATED
Conditions: Osteonecrosis of the Femoral Head
Interventions: DRUG: Core decompression/PREOB® implantation|DRUG: Core decompression/placebo implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rivaroxaban in Type 2 Myocardial Infarctions
Status: COMPLETED
Conditions: Type II Myocardial Infarction
Interventions: DRUG: Rivaroxaban 2.5 MG [Xarelto]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sexual Education Based on the PLISSIT Model on Sexual Function, Attitudes Towards Sexuality and Sexual Distress in Pregnant Women
Status: ENROLLING_BY_INVITATION
Conditions: Healthy|Pregnancy Related|Stress
Interventions: BEHAVIORAL: PLISSIT model based sexual health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevalence of Chronic Obstructive Pulmonary Disease (COPD) and Eosinophilia Among Primary Care Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: OTHER: Minimal questionnaire|OTHER: Medical interview|OTHER: CAT|PROCEDURE: Blood test|OTHER: anthropometric measures|OTHER: Oximetry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Optimal MTX Dose as an Add-on Therapy to Adalimumab for RA Patients in Japan, South Korea and Taiwan
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Methotrexate|DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Revatio for Heart Disease in Duchenne Muscular Dystrophy and Becker Muscular Dystrophy
Status: TERMINATED
Conditions: Duchenne Muscular Dystrophy|Becker Muscular Dystrophy
Interventions: DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intracavernosal as add-on Therapy to Sildenafil 100 mg on Demand Compared to Sildenafil 100 mg on Demand for the Treatment of Erectile Dysfunction (ED) Not Sufficiently Responsive to Standard Therapy With Phosphodiesterase Type 5 Inhibitors
Status: ACTIVE_NOT_RECRUITING
Conditions: Erectile Dysfunction
Interventions: DRUG: Investigational product administration Xeomin® (MERZ PHARMACEUTICALS GMBH)|DRUG: Placebo administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kuvan® in Phenylketonuria Patients Less Than 4 Years Old
Status: COMPLETED
Conditions: Phenylketonuria
Interventions: DRUG: Kuvan®|OTHER: Phenylalanine (Phe)-restricted diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenetics of Anastrozole in Postmenopausal Women With Estrogen Receptor-Positive and/or Progesterone Receptor-Positive Stage I, Stage II, or Stage III Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: GENETIC: Single nucleotide polymorphism (SNP)|OTHER: high performance liquid chromatography|OTHER: measurements by DXA|OTHER: questionnaire administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacological Management of Delirium
Status: COMPLETED
Conditions: Delirium|Cognitive Impairment
Interventions: BEHAVIORAL: Reduced exposure to anticholinergics|PROCEDURE: Reduced exposure to benzodiazepines|DRUG: Haloperidol|PROCEDURE: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genicular Artery Embolization (GAE) for the Treatment of Chronic Post Knee Arthroplasty Pain
Status: WITHDRAWN
Conditions: Knee Pain Chronic|Knee Swelling Pain|Arterial Occlusion
Interventions: DEVICE: Embozene Microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Four Types of Single Dose Hyaluronic Acid Injection in Patients With Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DRUG: Crespine gel|DRUG: Intragel|DRUG: Crespine plus gel|DRUG: Monovisc
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Immunogenicity of Apical Membrane Antigen 1 (PfAMA-1-FVO[25-545])
Status: UNKNOWN
Conditions: Malaria
Interventions: BIOLOGICAL: Malaria vaccine AMA1 (PfAMA-1-FVO[25-545]|BIOLOGICAL: AMA1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Migraine With Aura and Patent Foramen Ovale: Identification of Biomarkers to Select Patients In Whom Intervention Would Be Beneficial (MANET)
Status: RECRUITING
Conditions: Migraine Headache|PFO - Patent Foramen Ovale
Interventions: OTHER: blood samples collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Immediate Versus South African Recommendations Guided ART Initiation on HIV Incidence
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Immediate ARV treatment initiation with TDF/FTC/EFV|OTHER: South African recommendation guided ARV (TDF/FTC/EFV) initiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Self-directed Mobile Mindfulness Intervention to Address Distress and Burnout in Frontline Healthcare Workers
Status: COMPLETED
Conditions: Emotional Distress|Burnout, Professional|Stress, Job|Anxiety|Depressive Symptoms
Interventions: BEHAVIORAL: LIFT Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual Site-Dual Channel Non-invasive Brain Stimulation for Language and Cognitive Function in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: IFG stimulation|DEVICE: DLPFC stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Performance and Efficiency of Zirconia Crowns in Treating Primary Teeth
Status: COMPLETED
Conditions: Primary Teeth
Interventions: DEVICE: Locally Made Zirconia Crowns|DEVICE: ZR Zirconia Crwons NuSmile ® Crowns
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Study Comparing Colon Evaluation With The Pure-Vu System To A Standard Colonoscopy In Patients Who Are High Risk For Inadequate Bowel Preparation
Status: WITHDRAWN
Conditions: Gastrointestinal Disease|Colorectal Cancer
Interventions: DEVICE: Pure-Vu System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Decrease in Blood Pressure in PARQVE
Status: UNKNOWN
Conditions: Knee Osteoarthritis|Blood Pressure
Interventions: BEHAVIORAL: ABPM|BEHAVIORAL: The arterial stiffness and endothelial reactivity|BEHAVIORAL: Euroqol EQ-5D-5L|BEHAVIORAL: Lectures about knee OA|BEHAVIORAL: Continuous intensity exercise|BEHAVIORAL: Exercises with varying intensity and interval
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sclerotherapy of Internal Spermatic Veins in Patients With Varicocele and Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: venographic occlusion of spermatic veins
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Wearing Face Masks on Salivary Parameters and Halitosis
Status: COMPLETED
Conditions: Dry Mouth|Halitosis
Interventions: DEVICE: DIY face mask|DEVICE: Surgical face mask|DEVICE: FFP2 respirator mask|OTHER: Waiting for 4 hours without wearing a mask|OTHER: Use of fluoridated toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of the Safety and Effectiveness of Doripenem in Filipino Patients With Nosocomial Pneumonia, Complicated Intra-Abdominal Infections and Complicated Urinary Tract Infections
Status: COMPLETED
Conditions: Pneumonia, Bacterial|Nosocomial Infection|Intraabdominal Infections|Urinary Tract Infection
Interventions: DRUG: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Assessing The Interest of Indocyanine Green Fluorescence Imaging With Radioisotope Method For Sentinel Lymph Node Biopsy in Patients With Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: indocyanine green|DRUG: isotope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Automated Adjustment of Inspired Oxygen With Combined Adaptive Mechanical Backup Ventilation as Compared to Automated Oxygen Adjustment Alone in Preterm Infants With Intermittent Hypoxemic Events During Non-invasive Ventilatory Support
Status: UNKNOWN
Conditions: Apnea, Hypoxia
Interventions: DEVICE: Saturation sensitive backup ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET-MRI for Functional Imaging of the Testis: A Feasibility Study
Status: WITHDRAWN
Conditions: Infertility|Non-obstructive Azoospermia|Vasectomy
Interventions: DEVICE: PET/ MRI of the Testis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Is Topiramate Effective in Treating Dizziness in Patient's With Migraine-Associated Dizziness
Status: WITHDRAWN
Conditions: Migraine|Headache|Dizziness
Interventions: DRUG: topiramate|DRUG: lactulose placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Randomized, Comparative 3-Way Cross-Over Study to Evaluate the Effect of Food on the 24-Hour Intragastric pH at Day 5 After Twice Daily Oral Administration of PN 200 (Omeprazole/Naproxen) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PN 200
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of NNC0114-0006 at Increasing Dose Levels in Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Inflammation|Rheumatoid Arthritis
Interventions: DRUG: NNC0114-0006|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Rapid and Slow Maxillary Expansion in Treating Posterior Crossbite
Status: COMPLETED
Conditions: Posterior Crossbite
Interventions: PROCEDURE: Rapid Maxillary Expanding Device|PROCEDURE: Slow Maxillary Expanding Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Naltrexone for Problem Drinkers
Status: COMPLETED
Conditions: Alcoholism|Alcohol Drinking|Alcohol Dependence
Interventions: DRUG: Naltrexone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ginsenoside H Dripping Pills for Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Ginsenoside H dripping pills|DRUG: Ginsenoside H dripping pills+Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine and Pseudomonas Aeruginosa Combination in Metastatic Breast Cancer (MBC)
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: capecitabine and pseudomonas aeruginosa combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer
Status: COMPLETED
Conditions: Breast Cancer|Chronic Myeloproliferative Disorders|Gestational Trophoblastic Tumor|Kidney Cancer|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Neuroblastoma|Ovarian Cancer|Sarcoma|Testicular Germ Cell Tumor
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: recombinant interferon alfa|BIOLOGICAL: sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Nebulized Midazolam, Dexmedetomidine, and Their Combination in Sedation of Preschoolers Undergoing Dental Treatment
Status: COMPLETED
Conditions: Dental Anxiety
Interventions: DRUG: Midazolam group (MDZ)|DRUG: Dexmedetomidine group (DEX)|DRUG: Combination of Midazolam and Dexmedetomidine (MDZ/DEX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of Azidothymidine Plus Methadone in Patients With AIDS and AIDS Related Complex (ARC)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Methadone hydrochloride|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: 12 Week Safety Trial of Flibanserin in Depressed Women Taking an SSRI or SNRI With Decreased Sexual Desire and Distress
Status: TERMINATED
Conditions: Sexual Dysfunctions, Psychological|Depression
Interventions: DRUG: flibanserin 50 mg to 100 mg qhs|DRUG: flibanserin 100 mg qhs|DRUG: placebo 2 tablets qhs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IV Ferric Carboxymaltose Compared With Oral Iron in the Treatment of Iron Deficiency Anemia at Delivery in Tanzania
Status: UNKNOWN
Conditions: Iron-Deficiency Anemia
Interventions: DRUG: Ferric carboxymaltose|DRUG: Ferrous sulfate + folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics Effect on the Female Urinary Microbiome ProFUM Trial (Probiotics Effect on the Female Urinary Microbiome)
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Probiotic in Dry Eye Syndromes
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DRUG: Ophthalmic Probiotic|DRUG: Opthalmic Placebo|DIETARY_SUPPLEMENT: Oral Probiotic Capsule|DIETARY_SUPPLEMENT: Oral Placebo Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Short Course FOLFOX Chemotherapy With Either Nivolumab or Nivolumab + Radiation in the First Line Treatment of Metastatic or Unresectable Gastroesophageal Cancers (BMS Protocol CA209-76L)
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastroesophageal Adenocarcinoma
Interventions: DRUG: Nivolumab 240 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cholesterol-lowering Effects of Plant Stanol Ester
Status: COMPLETED
Conditions: Dyslipidemias|Hypercholesterolemia|Hyperlipidemias
Interventions: DIETARY_SUPPLEMENT: Plant stanol ester|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Whole-Neck Computed Tomography Perfusion Scan in Imaging Patients With Head and Neck Tumors
Status: COMPLETED
Conditions: Head and Neck Neoplasm|Malignant Head and Neck Neoplasm
Interventions: RADIATION: Computed Tomography Perfusion Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nicotine Pharmacokinetics Following Use of the P4M3 Gen 2.0 E-Cigarette Compared to Smoking Cigarettes
Status: COMPLETED
Conditions: Nicotine Vaping|Nicotine|Vaping
Interventions: OTHER: CA35|OTHER: CM35|OTHER: Cig
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of the Safety and Effectiveness of Synvisc-One® (Hylan G-F 20) in Patients With Primary Osteoarthritis of the Hip
Status: COMPLETED
Conditions: Osteoarthritis, Hip
Interventions: DEVICE: Synvisc-One (hylan G-F 20)|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Extension Study to Evaluate the Safety, Tolerability and Activity of Oral Fampridine-SR Tablets in Multiple Sclerosis Patients Who Participated in the MS-F203 Trial
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Fampridine-SR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring Advanced Imaging Techniques to Characterize Botulinum Toxin Diffusion in Human Muscle
Status: COMPLETED
Conditions: Stroke|Muscle Spasticity
Interventions: DRUG: Botox (botulinum toxin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Dose-escalation Study to Investigate Safety and Toleration of OZ439
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: OZ439
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Targeted Agent Evaluation in Digestive Cancers in China Based on Molecular Characteristics
Status: RECRUITING
Conditions: Biliary Tract Neoplasms|Gastric Cancer|Esophageal Squamous Cell Carcinoma|Colorectal Cancer|Gastrointestinal Stromal Tumors|Pancreatic Cancer|Neuroendocrine Tumors|Unknown Primary Cancer|Digestive Cancer
Interventions: DRUG: FGFR Inhibitor, IDH1 Inhibitor, HER2 Inhibitor, PARP Inhibitor, BRAF Inhibitor, MEK Inhibitor, ICIs, EGFR-TKIs, NTRK-TKI, and et. al.|DRUG: Other Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Adult and Adolescent Subjects With Seasonal Allergic Rhinitis (SAR)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis|Hay Fever
Interventions: DRUG: Beclomethasone dipropionate|DRUG: Placebo Nasal Aerosol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Skeletonised Versus Pedicled Internal Thoracic Artery
Status: COMPLETED
Conditions: Heart Diseases
Interventions: PROCEDURE: Pedicled|PROCEDURE: Surgical skeletonised|PROCEDURE: Thunderbeat skeletonised
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Detection of Liver Cancer by QUS
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Liver Cancer
Interventions: DIAGNOSTIC_TEST: Quantitative Ultrasound|DIAGNOSTIC_TEST: B-mode Ultrasound|DIAGNOSTIC_TEST: Magnetic Resonance Imaging|DIAGNOSTIC_TEST: Liver Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Influence of Multi-domain Cognitive Training on Large-scale Structural and Functional Brain Networks in MCI
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Multi-domain cognitive training|BEHAVIORAL: Cross-word puzzle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dietary Patterns, Sodium Intake and Blood Pressure (DASH - Sodium)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Hypertension|Vascular Diseases
Interventions: BEHAVIORAL: diet, fat-restricted|BEHAVIORAL: diet, sodium-restricted
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: Evaluation of Pain Level Reduction After Low-dose Radiation in Symptomatic Facet Joint Arthritis
Status: RECRUITING
Conditions: Lower Back Pain Chronic|Facet Joint Arthrosis|Osteoarthritis, Spine
Interventions: DRUG: Intra-articular steroid injections|RADIATION: Low-dose radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TSR-022 (Anti-TIM-3 Antibody) and TSR-042 (Anti-PD-1 Antibody) in Patients With Liver Cancer
Status: RECRUITING
Conditions: Adult Primary Liver Cancer|Advanced Adult Primary Liver Cancer|Localized Unresectable Adult Primary Liver Cancer
Interventions: DRUG: TSR-022 and TSR-042
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Design of a Closed-loop Controller Based on the Bispectral Index (BIS) Effectiveness of the Smith Predictor
Status: UNKNOWN
Conditions: General Anesthesia
Interventions: DRUG: Propofol|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Single-arm Exploratory Study of Neoadjuvant Therapy
Status: RECRUITING
Conditions: Lung Adenocarcinoma
Interventions: DRUG: Tislelizumab|DRUG: pemetrexed|DRUG: cis-platemum|DRUG: or carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vedolizumab Subcutaneous (SC) Versus Intravenous (IV) in Ulcerative Colitis or Crohn's Disease
Status: WITHDRAWN
Conditions: Ulcerative Colitis|Crohn's Disease
Interventions: DRUG: Vedolizumab intravenous injection|DRUG: Vedolizumab subcutaneous injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Heart Rate Control With Ivabradine on Hemodynamic in Patients With Sepsis
Status: RECRUITING
Conditions: Sepsis|Ivabradine|Hemodynamics|Heart Rate Control
Interventions: DRUG: Ivabradine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Foot and Lower Extremity Exercises in Adolescents With Pes Planovalgus
Status: NOT_YET_RECRUITING
Conditions: Flat Foot
Interventions: OTHER: Foot exercise|OTHER: Lower Extremity Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT