pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: the Use of Harmonic Scalpel Versus Knot Tying for Total Thyroidectomy
Status: COMPLETED
Conditions: Thyroid Swelling
Interventions: PROCEDURE: HS total thyroidectomy|PROCEDURE: conventional total thyroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Elafibranor Pharmacokinetic Parameters in Renal Impaired Patients
Status: COMPLETED
Conditions: Renal Impairment|Renal Insufficiency|Kidney Diseases|Pharmacokinetics
Interventions: DRUG: Elafibranor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Study of ET1402L1-CAR T Cells in AFP Expressing Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma|Liver Cancer|Liver Neoplasms|Metastatic Liver Cancer
Interventions: BIOLOGICAL: autologous ET1402L1-CART cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate The Relationship Between Plasma Drug Levels And Receptor Binding In Brain Using PET (Positron Emission Tomography) In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-05212365
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimizing Expectations in Cardiac Surgery Patients
Status: COMPLETED
Conditions: Coronary Artery Bypass Graft Surgery (CABG)|Patients' Expectations|Coronary Heart Disease
Interventions: BEHAVIORAL: Expectation Manipulation Intervention|BEHAVIORAL: Supportive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Potential of ctDNA-MRD for Recurrence Surveillance and Prognostic Evaluation in High-risk Endometrial Cancer
Status: RECRUITING
Conditions: Endometrial Cancer
Interventions: DIAGNOSTIC_TEST: MRD-ctDNA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study of the Relation Between the Fat Infiltration of the Multifidus Muscle and the Lumbar Foraminal Stenosis, by 2D and 3D Segmentation
Status: NOT_YET_RECRUITING
Conditions: Low Back Pain|Degenerative Condition, Neurologic
Interventions: OTHER: Spine surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of DSP-5336 in Relapsed/Refractory AML/ ALL With or Without MLL Rearrangement or NPM1 Mutation
Status: RECRUITING
Conditions: Leukemia, Myeloid, Acute|Leukemia, Lymphocytic, Acute
Interventions: DRUG: DSP-5336
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Systemic Acetaminophen to Improve Postoperative Quality of Recovery After Ambulatory Breast Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: IV acetaminophen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of SRX246 Capsules in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SRX246|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study Comparing Tazarotene Cream 0.1% to Tazorac® and Both to a Placebo Control in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Tazarotene Cream 0.1%|DRUG: Tazorac®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study to Evaluate the Efficacy and Safety of MBA-P01 in Subjects With Moderate to Severe Glabellar Lines
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: DRUG: MBA-P01 (Botulinum toxin A)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parent Intervention for Psychiatrically-Hospitalized Youth
Status: RECRUITING
Conditions: Adolescent - Emotional Problem|Suicide and Self-harm|Parenting
Interventions: BEHAVIORAL: DBT-Based Parenting Intervention|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Coping With Covid-19: Loneliness, Self-Efficacy, Social Support, Depression & Anxiety in Patients in Medical Rehab.
Status: RECRUITING
Conditions: Loneliness|Depression, Anxiety|Self Efficacy|Social Support|Covid19|Psychology
Interventions: BEHAVIORAL: Intervention 1: According to DGP|BEHAVIORAL: Intervention 2: According to Cacioppo "E.A.S.E."
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Entinostat in Chinese Postmenopausal Women Patients With Locally Recurrent or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Entinostat|DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Posterior Parietal Cortex and Cerebellum Anodal tDCS on Ankle Tracking Visuomotor Adaptation
Status: COMPLETED
Conditions: Transcranial Direct Current Stimulation
Interventions: DEVICE: Transcranial direct current stimulation (Anodal)|DEVICE: Transcranial direct current stimulation (Sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies
Status: COMPLETED
Conditions: Acute Myeloid Leukemia With FLT3/ITD Mutation|Acute Myeloid Leukemia With Gene Mutations|Acute Myeloid Leukemia With Inv(3) (q21.3;q26.2); GATA2, MECOM|Acute Myeloid Leukemia With t(6;9) (p23;q34.1); DEK-NUP214|Aplastic Anemia|Chronic Lymphocytic Leukemia|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Chronic Myelomonocytic Leukemia|Follicular Lymphoma|Hodgkin Lymphoma|Myelodysplastic Syndrome|Myelofibrosis|Myeloid Leukemia|Non-Hodgkin Lymphoma|Plasma Cell Myeloma|Polycythemia Vera|Recurrent Adult Acute Myeloid Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Therapy-Related Acute Myeloid Leukemia
Interventions: DRUG: Fludarabine phosphate|DRUG: Busulfan|RADIATION: Total-Body Irradiation|BIOLOGICAL: Therapeutic Allogeneic Lymphocytes|DRUG: Cyclophosphamide|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|PROCEDURE: Peripheral Blood Stem Cell Transplantation|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy for Relapsed Epstein Barr Virus Associated Lymphoma
Status: TERMINATED
Conditions: Epstein Barr Virus Associated Non Hodgkin's Lymphoma|Epstein Barr Virus Associated Hodgkin's Lymphoma|Post-Transplant Lymphoproliferative Disease
Interventions: DRUG: Doxorubicin|DRUG: Methotrexate|DRUG: Leucovorin|BIOLOGICAL: Hydroxyurea|DRUG: Zidovudine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Phase 1b Study of ARQ 092 in Combination With Anastrozole
Status: TERMINATED
Conditions: Solid Tumors|Ovarian Cancer|Endometrial Cancer
Interventions: DRUG: ARQ 092 + carboplatin + paclitaxel (Closed)|DRUG: ARQ 092 + paclitaxel (Closed)|DRUG: ARQ 092 + anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FOLFIRI or Modified FOLFIRI and Veliparib as Second Line Therapy in Treating Patients With Metastatic Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Pancreatic Adenocarcinoma|Recurrent Pancreatic Carcinoma|Stage IV Pancreatic Cancer AJCC v6 and v7
Interventions: DRUG: Fluorouracil|DRUG: Fluorouracil|DRUG: Irinotecan Hydrochloride|OTHER: Laboratory Biomarker Analysis|DRUG: Leucovorin Calcium|DRUG: Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Conditioning Paired With Endovascular Treatment for Acute Ischemic Stroke
Status: UNKNOWN
Conditions: Acute Stroke
Interventions: DEVICE: Remote ischemic conditioning.|PROCEDURE: Endovascular treatment.|DEVICE: Sham remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acceptance and Commitment Therapy and Compassion-Based Virtual Group Therapy to Improve Psychological Wellbeing in Patients With Cancer
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid System Neoplasm|Malignant Solid Neoplasm
Interventions: BEHAVIORAL: Behavioral Intervention: Group Therapy Session|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Kinesio-Taping in Stroke Patients With Visuospatial Neglect
Status: UNKNOWN
Conditions: Stroke|Motor Disorder
Interventions: OTHER: Kinesio taping group|OTHER: Sham Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Exploratory Study on the Biological Function of Dendritic Cells In Vivo Supported by Nicotinamide Mononucleotide (Vital NAD)
Status: NOT_YET_RECRUITING
Conditions: Postoperative Prevention of Tumor
Interventions: DRUG: Oral NMN combined with DC cell vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OTO-201 for the Treatment of Middle Ear Effusion in Pediatric Subjects Requiring Tympanostomy Tube Placement
Status: COMPLETED
Conditions: Otitis Media With Effusion
Interventions: DRUG: OTO-201|DRUG: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Short Term Dabigatran Etexilate Followed by Aspirin Monotherapy After LAA (Left Atrial Appendage) Device Closure (the DEA-LAA Study).
Status: COMPLETED
Conditions: Atrial Fibrillation|Device Related Thrombus|Left Atrial Appendage Thrombosis|Watchman LAA Closure Device
Interventions: DRUG: Dabigatran Etexilate Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluating Oral Peri-operative Acetylsalicylic Acid in Subjects Undergoing Endovascular Coiling-only of Unruptured Brain Aneurysms
Status: RECRUITING
Conditions: Unruptured Cerebral Aneurysm
Interventions: DRUG: Acetyl Salicylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combining PD-1 Blockade, CD137 Agonism and Adoptive Cell Therapy for Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)|Skin Cancer
Interventions: DRUG: Nivolumab|PROCEDURE: Surgery to Remove Tumor for Growth of TIL|DRUG: CD137|DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: TIL Infusion|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAEB071 Thorough QTc Study in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: sotrastaurin|DRUG: sotrastaurin|DRUG: placebo to sotrastaurin|DRUG: Avelox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Indications and Outcomes of Endoscopic Ultrasound in Tanta
Status: UNKNOWN
Conditions: Gastric Disease|Intestinal Disease|Pancreatic Diseases|Esophageal Diseases
Interventions: DEVICE: Endoscopic Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Carboplatin in Treating Patients With Recurrent High-Grade Gliomas
Status: COMPLETED
Conditions: Adult Anaplastic Astrocytoma|Adult Anaplastic Oligodendroglioma|Recurrent Adult Brain Tumor
Interventions: DRUG: carboplatin|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Assess Vagus Nerve Stimulation Therapy vs. Anti-Epileptic Drug (AED) Treatment in Children With Refractory Seizures
Status: TERMINATED
Conditions: Epilepsy
Interventions: DEVICE: Vagus Nerve Stimulation (VNS) Therapy|DRUG: Anti-Epileptic Drug (AED)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Smoking on Clinical, Microbiological and Immunologic Parameters in Patients With Aggressive Periodontitis.
Status: UNKNOWN
Conditions: Periodontal Diseases|Aggressive Periodontitis
Interventions: DRUG: full mouth ultrassonic debridement associated to Amoxicilin 500 + Metronidazole 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Drug Interaction Study Between Gemigliptin and Glimepiride in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Gemigliptin and Glimepiride|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Subsartorial Saphenous Block on Postoperative Pain Following Major Ankle and Hind Foot Surgery
Status: COMPLETED
Conditions: Arthrosis|Arthritis
Interventions: DRUG: Bupivacaine-epinephrine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Registry of Seraph®-100 Microbind® Affinity Blood Filter for COVID-19 Under EUA
Status: ENROLLING_BY_INVITATION
Conditions: COVID-19|SARS-CoV 2
Interventions: DEVICE: Seraph®-100 Microbind® Affinity Blood Filter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neoadjuvant Anti-PD-1 and TP Versus TPF on Pathological Response in OSCC
Status: RECRUITING
Conditions: Oral Squamous Cell Carcinoma|Neoadjvant Therapy|Anti-PD-1|Chemotherapy
Interventions: DRUG: Toripalimab (anti-programmed death-1 inhibitor)|DRUG: Albumin paclitaxel|DRUG: Cisplatin|DRUG: Docetaxel|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Intravenous Immunoglobulin (IVIG) for Desensitization in Renal Transplantation
Status: COMPLETED
Conditions: Kidney Transplant
Interventions: DRUG: IVIG and Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted Perfusion Based Haemodynamic Management in Critically Ill Patients Using Urethral Perfusion
Status: RECRUITING
Conditions: Critically Ill
Interventions: DRUG: 250 ML NaCl 4.5 MG/ML Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multimedia Intervention in Patients With Familial Adenomatous Polyposis (FAP)
Status: COMPLETED
Conditions: Familial Adenomatous Polyposis|Colorectal Cancer
Interventions: BEHAVIORAL: Web-Based Multimedia Intervention|BEHAVIORAL: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assess the Immunogenicity of the Human Rotavirus (HRV) Vaccine After Reconstitution Without Buffering Agent; & Evaluate the Immunogenicity, Reactogenicity & Safety of the Vaccine After Storage for 7 d at 37°C Following 2 Doses in Healthy Infants
Status: COMPLETED
Conditions: Rotavirus Gastroenteritis
Interventions: BIOLOGICAL: Live attenuated human rotavirus vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: The Contribution of Incretin Hormones to the Amelioration of Glucose Metabolism After Roux-en-Y Gastric Bypass
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Exendin 9,39|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low Molecular Weight Heparin for 72 Hours Followed by Dabigatran for Acute Intermediate-Risk Pulmonary Embolism.
Status: TERMINATED
Conditions: Pulmonary Embolism
Interventions: DRUG: Dabigatran
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NBTXR3, Radiation Therapy, and Pembrolizumab for the Treatment of Recurrent or Metastatic Head and Neck Squamous Cell Cancer
Status: RECRUITING
Conditions: Metastatic Head and Neck Squamous Cell Carcinoma|Recurrent Head and Neck Squamous Cell Carcinoma
Interventions: OTHER: Hafnium Oxide-containing Nanoparticles NBTXR3|RADIATION: Hypofractionated Radiation Therapy|BIOLOGICAL: Pembrolizumab|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety and Efficacy of Fexofenadine Hydrochloride (HCL) + Pseudoephedrine HCL Fixed Dose Combination in Indian Male and Female Participants With Allergic Rhinitis (AR) Who Are 12 Years and Above
Status: NOT_YET_RECRUITING
Conditions: Rhinitis Allergic
Interventions: DRUG: Fexofenadine HCL and pseudoephedrine HCL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of B-701 in Combination With Pembrolizumab in Treatment of Locally Advanced or Metastatic Urothelial Cell Carcinoma
Status: TERMINATED
Conditions: Locally Advanced or Metastatic Urothelial Cell Carcinoma|Urinary Bladder Disease|Urological Diseases
Interventions: DRUG: B-701|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of TongBi Capsule in Patients With Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DRUG: Treatment of TongBi Capsule|DRUG: Treatment of TongBi placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy on Overweight With Oral Supplemenation of Probiotics and Prebiotics
Status: COMPLETED
Conditions: Overweight
Interventions: DIETARY_SUPPLEMENT: Study product A (Wonderlab wonder4shape)|DIETARY_SUPPLEMENT: Study product B (Wonderlab wonder4shape)|DIETARY_SUPPLEMENT: Study product C (Wonderlab wonder4shape)|DIETARY_SUPPLEMENT: Study product D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Relative Oral Bioavailability of the Antiflu Medicine Oseltamivir in the Intensive Care Unit
Status: WITHDRAWN
Conditions: Influenza A Virus Infection|Influenza B Virus Infection
Interventions: DRUG: Oseltamivir 75 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacodynamic Effects of Ranolazine Versus Amlodipine on Platelet Reactivity
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Ranolazine|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Imaging Immune Activation in HIV by PET-MR
Status: RECRUITING
Conditions: HIV Infections
Interventions: DRUG: [18F]F-AraG (2'-deoxy-2'-fluoro-9-β-D-arabinofuranosylguanine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Dose-Finding Study of GSK2894512 Cream in Subjects With Atopic Dermatitis (AD)
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: GSK2894512 1% Cream|DRUG: GSK2894512 0.5% Cream|DRUG: Vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RCT Measuring the Effect of the ERVIN Software
Status: COMPLETED
Conditions: Decision Making, Shared|Arthroplasty, Replacement, Knee|Arthroplasty, Replacement, Hip|Osteoarthritis, Knee|Osteoarthritis, Hip|Artificial Intelligence
Interventions: OTHER: ERVIN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: EUS Guided Liver Biopsy - Will it Give Better Yield, More Tissue With Less Complication?
Status: COMPLETED
Conditions: NAFLD|Alcoholic Hepatitis
Interventions: DEVICE: Endoscopic USG guided Liver biopsy|DEVICE: Percutaneous Liver Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Evaluation of NiTiDent Tuah Porous NiTi Dental Implants
Status: UNKNOWN
Conditions: Partial-edentulism
Interventions: DEVICE: NiTiDent Tuah Porous NiTi Dental Implants|DEVICE: Control Dental Implant Systems
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Children and Adolescents With Dental Anxiety - Randomized Controlled Study of Cognitive Behavioral Therapy
Status: COMPLETED
Conditions: Dental Anxiety
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Support Devices for Ventilator-Assisted ICU Patients
Status: ENROLLING_BY_INVITATION
Conditions: Device Dislocation
Interventions: DEVICE: improved version_support device|DEVICE: the NTUH version_support device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prevention of Complications (SARS-CoV-2): Clinical Study
Status: COMPLETED
Conditions: Complication
Interventions: DRUG: Control group (standard hospital treatment)|DRUG: Group Hydroxychloroquine|DRUG: Group Hydroxychloroquine and apixaban|DRUG: Group Apixaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dose-Escalation Study of CG0070 for Bladder Cancer After BCG (Bacillus Calmette-Guerin) Failure
Status: UNKNOWN
Conditions: Carcinoma, Transitional Cell|Bladder Neoplasms
Interventions: BIOLOGICAL: Oncolytic adenovirus (serotype 5) - CG0070
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of a Conventional and Flexible Extended Oral Contraceptive of EE/DRSP With or Without Metafolin in Latin America
Status: WITHDRAWN
Conditions: Contraception
Interventions: DRUG: EE20/DRSP (BAY86-5300)|DRUG: EE20/DRSP/L-5-MTHF (BAY98-7071)|DRUG: EE20/DRSP/L-5-MTHF (BAY98-7071) + L-5-MTHF (BAY86-7660)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of Adjuvant Lapatinib In High-Risk Head And Neck Cancer Subjects After Surgery
Status: COMPLETED
Conditions: Neoplasms, Head and Neck
Interventions: DRUG: Lapatinib|RADIATION: Chemoradiation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ORal anticoaGulants in diAbetic and Nondiabetic Patients With nOn-valvular Atrial fibrillatioN (ORGANON)
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: Dabigatran|DRUG: Apixaban|DRUG: Rivaroxaban|DRUG: Edoxaban|DRUG: Warfarin|DRUG: Acenocumarole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Concurrent Administration of Influenza Vaccine in Patients Undergoing Anti-PD-1 Immunotherapy (Nivolumab, Pembrolizumab)
Status: COMPLETED
Conditions: Influenza Virus Vaccine Adverse Reaction (Disorder)|Influenza|Malignancy
Interventions: BIOLOGICAL: influenza vaccination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Compare Safety and Pharmacokinetics of "CG1801" and "CGL1802" in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CG1801|DRUG: CGL1802
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sevelamer on Glucose Tolerance and Insulin Sensitivity in Patients With Chronic Renal Failure (CKD)
Status: WITHDRAWN
Conditions: Kidney Failure, Chronic|End-Stage Renal Disease|Insulin Resistance|Hyperphosphatemia
Interventions: DRUG: Sevelamer|DRUG: Calcium carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Methylprednisolone in the Treatment of Patients With Ocular Involvement in Behcet's Disease
Status: UNKNOWN
Conditions: Behcet's Disease
Interventions: DRUG: methylorednisolone|OTHER: dextrose water 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Randomized Control Trial to Help Youth Smokers to Quit Smoking:
Status: UNKNOWN
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Adventure-based intervention group|BEHAVIORAL: WhatsApp intervention group|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Fenfluramine (Hydrochloride) in Infants 1 Year to Less Than 2 Years of Age With Dravet Syndrome
Status: RECRUITING
Conditions: Dravet Syndrome
Interventions: DRUG: fenfluramine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does the Addition of Manipulation Provide Added Benefit to Massage Therapy for Tension-type Headache Patients?
Status: COMPLETED
Conditions: Tension-type Headache
Interventions: OTHER: Massage|OTHER: Occiput-Atlas-Axis Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telemental Health and Cognitive Processing Therapy for Rural Combat Veterans With Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Cognitive Processing Therapy Group Videoteleconference|BEHAVIORAL: Cognitive Processing Therapy Group In-Person
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Braun Anastomosis on Reduction in Delayed Gastric Emptying Following Pancreaticoduodenectomy
Status: COMPLETED
Conditions: Periampullary Pathology Requiring Pancreaticoduodenectomy
Interventions: PROCEDURE: PPPD with Braun anastomosis|PROCEDURE: conventional PPPD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prospective Randomized Clinical Trial on Oral and Intravenous Antibiotic Prophylaxis in Colorectal Surgery.
Status: COMPLETED
Conditions: Colorectal Surgery
Interventions: DRUG: Oral antibiotic drugs|DRUG: Parenteral prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of 9-valent Human Papillomavirus (9vHPV) Vaccine Coadministered With Messenger Ribonucleic Acid (mRNA)-1273 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) (COVID-19) Vaccine (V503-076)
Status: COMPLETED
Conditions: Papillomavirus Infections|Coronavirus Disease (COVID-19)
Interventions: BIOLOGICAL: 9vHPV Vaccine|BIOLOGICAL: mRNA-1273 Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Assess Efficacy and Safety of Zoledronic Acid and the Value of Markers of Bone Resorption in the Prediction of Bone Metastases and Cancer Treatment-induced Bone Loss (CTIBL) in Patients With Prostate Cancer on Hormone Therapy
Status: COMPLETED
Conditions: Cancer Prostate
Interventions: DRUG: Zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Preferred Dose of the Drug, Lisinopril, for Preventing Urinary Toxicity Following Radiotherapy for Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Radiation Toxicity|Urinary Complication
Interventions: DRUG: Lisinopril Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Handwriting Training Program on Handwriting Performance in Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: interactive computerized handwriting training program|OTHER: traditional handwriting training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GH21 Combined With D-1553 in KRAS G12C Mutant Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced or Metastatic Solid Tumors Harboring KRAS G12C Mutation
Interventions: DRUG: GH21|DRUG: D-1553
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melatonin and DNA Damage Study
Status: COMPLETED
Conditions: Sleep Quality|DNA Damage Repair Deficiency|Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: Melatonin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Investigation of GT UrologIcal, LLC's Artificial Urinary Sphincter (RELIEF II)
Status: COMPLETED
Conditions: Male Stress Urinary Incontinence
Interventions: DEVICE: GTU Artificial Urinary Sphincter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Colistin Plus Rifampicin in MDR P. Aeruginosa and A. Baumanii
Status: UNKNOWN
Conditions: Drug Safety
Interventions: DRUG: Colistin|DRUG: Colistin plus Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Adjustable Gastric Banding Versus Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: PROCEDURE: Laparoscopic restrictive procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gingival Crevicular Fluid, Salivary, and Serum Biomarkers Levels in Periodontal Treatment
Status: COMPLETED
Conditions: Periodontal Health|Periodontitis
Interventions: PROCEDURE: Non-surgical periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Skull Deformation as a Non-invasive Intracranial Pressure (ICP) Measure
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage|Stroke|Stroke, Ischemic|Stroke Hemorrhagic|Intracranial Hypertension
Interventions: DEVICE: ICP wave morphology comparison between a non-invasive (Brain4care) and a invasive method
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Role of Neo-adjuvant Chemotherapy in Tongue Preservation in Locally Advanced Squamous Cell Carcinoma of Oral Tongue
Status: UNKNOWN
Conditions: Tongue Neoplasms|Squamous Cell Carcinoma|Anterior Tongue Squamous Cell Carcinoma
Interventions: DRUG: Docetaxel|DRUG: Cisplatin|DRUG: 5FU|RADIATION: Radiotherapy|PROCEDURE: Glossectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Treatment in Rectal Cancer With Radiotherapy Followed by Atezolizumab and Bevacizumab (TARZAN)
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Neoadjuvant Enoblituzumab vs SOC in Men With High-Risk Localized Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Enoblituzumab|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib Hydrochloride and Quinacrine Dihydrochloride in Stage IIIB-IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: erlotinib hydrochloride|DRUG: quinacrine dihydrochloride - Escalation dose|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|DRUG: quinacrine dihydrochloride - Extension dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of STM 434 Alone or in Combination With Liposomal Doxorubicin in Patients With Ovarian Cancer or Other Advanced Solid Tumors
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Endometrial Cancer|Solid Tumors
Interventions: DRUG: STM 434|DRUG: Liposomal doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adherence Improving Self-Management Strategy (AIMS) in Breast Cancer Patients Using Adjuvant Endocrine Treatment (AET)
Status: UNKNOWN
Conditions: Breast Cancer|Breast Neoplasms
Interventions: BEHAVIORAL: Adherence Improving self-Management Strategy|OTHER: Regular care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Hypocol® on Lipids in Subjects With Mild Hypercholesterolemia and Mildly Elevated Blood Glucose
Status: COMPLETED
Conditions: Hyperlipidemia|Glucose Metabolism Disorders
Interventions: DRUG: HYPOCOL®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Targeted Therapy and Avelumab in Merkel Cell Carcinoma
Status: RECRUITING
Conditions: Metastatic Merkel Cell Carcinoma
Interventions: DRUG: Avelumab|RADIATION: External Beam Radiation Therapy (EBRT)|RADIATION: Lutetium-177 (177Lu)-DOTATATE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DAOIB for the Treatment of Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DRUG: DAOIB|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of EBA-175 RII-NG Malaria Vaccine Administered Intramuscularly
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria
Interventions: BIOLOGICAL: Aluminum Phosphate|DRUG: Placebo|BIOLOGICAL: EBA-175 RII-NG Malaria Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Myofascial Release of Subscapularis Along With Shoulder Mobilization in Adhesive Capsulitis
Status: RECRUITING
Conditions: Adhesive Capsulitis of Shoulder
Interventions: OTHER: Myofascial release of subscapularis|OTHER: Maitland mobilization|OTHER: Stretching exercises|OTHER: Cold pack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Evaluating Bioequivalence Between Test and Reference Formulations of Vadadustat Tablets in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: vadadustat reference tablets|DRUG: vadadustat test tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of HA 330-II for Hemofiltration in Patients With ALF as a Bridge to Liver Transplantation .
Status: UNKNOWN
Conditions: Acute-On-Chronic Liver Failure
Interventions: DEVICE: HA 330-II|DRUG: Standard medical treatment (SMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of NPL-2003 in Adolescents With Obsessive Compulsive Disorder (OCD)
Status: TERMINATED
Conditions: Obsessive Compulsive Disorder
Interventions: DRUG: Minocycline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy and Safety of Ultrasound Guided Supraclavicular Block Combined With Either Intercostobrachialor Pec 11for Creation of Surgical Brachio-basilic Fistula in Chronic Renal Failure Patients on Hemodialysis
Status: COMPLETED
Conditions: Best Regional Nerve Block for Creation of Surgical Brachiobasilic Fistula
Interventions: PROCEDURE: regional anesthesia for the upper limb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: rTMS Posterior Parietal Cortex Modulation and Upper Limb Movement After Stroke
Status: UNKNOWN
Conditions: Stroke|Hemiparesis|Transcranial Magnetic Stimulation|Brain Connectivity
Interventions: DEVICE: repeated transcranial magnetic stimulation continuous theta-burst stimulation|DEVICE: SHAM repeated transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: HCV Group Evaluation and Treatment Uptake (HCV GET-UP) Intervention
Status: COMPLETED
Conditions: Hepatitis C|Substance Use Disorders
Interventions: BEHAVIORAL: HCV GET-Up (Group Evaluation and Treatment Uptake)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Ground Level Gait Training With Body Weight Support (BWS) and Functional Electrical Stimulation (FES)
Status: COMPLETED
Conditions: Hemiparesis|Stroke
Interventions: DEVICE: gait training on ground level using BWS|DEVICE: gait training on ground level using BWS associated to FES
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Riluzole Versus Placebo in the Treatment of Children and Adolescents With ASD
Status: COMPLETED
Conditions: Autism Spectrum Disorders
Interventions: DRUG: Riluzole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prolongation of Pregnancy in Preeclampsia by Therapeutic Lipid Apheresis
Status: COMPLETED
Conditions: Preeclampsia|Dyslipidemia|Proteinuria|Hypertension
Interventions: OTHER: lipid apheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microwave Ablation Versus Liver Resection For Early Hepatocellular Carcinoma in Patients With Borderline Liver Function
Status: RECRUITING
Conditions: Carcinoma, Hepatocellular
Interventions: PROCEDURE: Microwave ablation|PROCEDURE: Liver resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Manual Therapy in Patients With Tinnitus and Temporomandibular Joint Disorder.
Status: COMPLETED
Conditions: Tinnitus
Interventions: OTHER: Conventional Physiotherapy|OTHER: Specific Manual Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Open-Label Extension Study Of Gabapentin As Adjunctive Therapy In Japanese Pediatric Patients With Partial Seizures
Status: COMPLETED
Conditions: Epilepsies, Partial
Interventions: DRUG: gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Compare the Efficacy of Erbium-Yag Laser or CO2RE Intimate Laser With Sham (COER)
Status: COMPLETED
Conditions: Vaginal Atrophy
Interventions: DEVICE: CO2 intimate|DEVICE: Erbium-yag|DEVICE: CO2 intimate or Erbium-yag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Injection of ex Vivo Amplified G-CSF Mobilised Autologous Peripheral Blood Stem Cell Transplantation
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: PROCEDURE: autologous peripheral blood stem cell transplantation, ex vivo amplified
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diet and Plant Sterols in the Control of Cholesterolemia (DESCO)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Plant sterols 2.5 g/day|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Food Effect on Pharmacokinetic Profiles and Safety in Healthy Volunteers
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: CKD-383(Fed)|DRUG: CKD-383(Fasted)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Actinic Keratosis Study
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: 5-fluorouracil 5% cream|DRUG: Calcipotriol 0.005% ointment|DRUG: Vaseline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of High-Dose Chemotherapy + Rituximab and CHOP + Rituximab in High-Risk Follicular Lymphoma
Status: UNKNOWN
Conditions: Follicular Lymphoma
Interventions: PROCEDURE: High dose chemotherapy with autologous transplantation|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Language During Inhalational Induction
Status: NOT_YET_RECRUITING
Conditions: Emergence Delirium|Anesthesia; Adverse Effect
Interventions: BEHAVIORAL: Standard/common language during induction|BEHAVIORAL: Positive language during induction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Randomized, Double-blind Study of the Effects of Fenretinide Administered in Subjects With Obesity
Status: SUSPENDED
Conditions: Obesity|Insulin Resistance
Interventions: DRUG: Fenretinide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of CVI-VZV-001 for Prevention of Herpes Zoster in Healthy Adults Age 50 Years and Above
Status: RECRUITING
Conditions: Vaccine-Preventable Diseases|Herpes Zoster
Interventions: BIOLOGICAL: CVI-VZV-001|BIOLOGICAL: Shingrix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Efficacy and Safety of GSK3858279 in Diabetic Peripheral Neuropathic Pain
Status: RECRUITING
Conditions: Pain
Interventions: DRUG: GSK3858279|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT