pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Posterior Capsule Opacification and Optical Quality of Different Hydrophobic Acrylic Intraocular Lenses
Status: COMPLETED
Conditions: Posterior Capsule Opacification
Interventions: DEVICE: Implantation of an intraocular lenses: iMics 1 NY-60 & NY-60G
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Programmed Intermittent Bolus Dosing Versus Continuous Epidural Infusion for Epidural Analgesia in Abdominal Surgery.
Status: COMPLETED
Conditions: Pain, Acute
Interventions: DRUG: Bupivacaine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Preoxygenation Using THRIVE Versus Facemask in Parturients
Status: COMPLETED
Conditions: Preoxygenation
Interventions: DEVICE: Facemask preoxygenation|DEVICE: THRIVE preoxygenation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adenoma Detection Rate With Endocuff-Assisted Colonoscopy - an Italian Trial
Status: UNKNOWN
Conditions: Colorectal Cancer|Colorectal Adenoma|Colorectal Polyp|Colorectal Neoplasms
Interventions: PROCEDURE: Standard colonoscopy|DEVICE: ARC Endocuff Vision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Phase 2 Study of VELCADE Alone or VELCADE® Plus Docetaxel in Previously Treated Patients With Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: VELCADE™ (bortezomib) for Injection (formerly PS-341)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Calibration Study Comparing IkT-001Pro to Imatinib Mesylate 400mg
Status: ACTIVE_NOT_RECRUITING
Conditions: CML
Interventions: DRUG: Imatinib Mesylate|DRUG: IkT-001Pro
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Control Trial to Evaluate Effectiveness of a Case Managment Program Regarding Psychosocial Well-being and Disease Symptoms Health for Patients With Multimorbid Coronary Heart Disease (CHD) Patients (KHK ProMA)
Status: UNKNOWN
Conditions: Coronary Heart Disease|Multimorbidity
Interventions: BEHAVIORAL: Case Management "CM CHD"|BEHAVIORAL: Social Interaction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Endobronchial Valve for Bronchoscopic Lung Volume Reduction Surgery: A Prospective Pilot Study
Status: NOT_YET_RECRUITING
Conditions: Emphysema|Chronic Obstructive Pulmonary Disease
Interventions: PROCEDURE: bronchoscopic lung volume reduction surgery using endobronchial valve
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pentoxifylline and Late Onset Sepsis in Preterm Infants
Status: COMPLETED
Conditions: Neonatal Late Onset Sepsis
Interventions: DRUG: Pentoxifylline (PTX)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Symbiotics to Prevent Postoperative Infection in Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer|Surgical Site Infection
Interventions: DIETARY_SUPPLEMENT: symbiotic group|DIETARY_SUPPLEMENT: placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving Diabetes Care:Effectiveness of Physician Profiling and Care Coordination by a Diabetes Resource Nurse
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: OTHER: Medicare Claims Feedback|OTHER: Medical Record Review|OTHER: Diabetes Resource Nurse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions
Status: COMPLETED
Conditions: Parkinson Disease|Huntington Disease|Autistic Spectrum Disorders|Fragile X Syndrome|Alzheimer Disease|Mild Cognitive Impairment
Interventions: DRUG: [18F]FPEB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Reducing Risk of Dementia Through Deprescribing
Status: RECRUITING
Conditions: Dementia|Alzheimer Disease, Late Onset
Interventions: OTHER: Deprescribing of target anticholinergics|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: FOODLIT-Trial: Digital Behaviour Change Intervention to Improve Food Literacy Amidst the COVID-19 Pandemic
Status: COMPLETED
Conditions: Food Literacy|Food Habits|Behavior and Behavior Mechanisms|Eating Behavior
Interventions: BEHAVIORAL: Experimental Group|BEHAVIORAL: Comparison Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: MDMA-assisted Therapy in People With Anxiety Related to Advanced Stage Cancer
Status: TERMINATED
Conditions: Anxiety Disorder|Cancer
Interventions: DRUG: Stage 1 Active Methylenedioxymethamphetamine|DRUG: Stage 1 Low dose Methylenedioxymethamphetamine|BEHAVIORAL: Psychotherapy|DRUG: Stage 2 Active Methylenedioxymethamphetamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cyanoacrylate and Laser and Dentin Sensitivity
Status: COMPLETED
Conditions: Dentin Hypersensitivity|Dentin Sensitivity
Interventions: OTHER: Cyanoacrylate|RADIATION: Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Psoriatic Arthritis in Adults With Psoriasis: An Estimate From Dermatology Practice
Status: COMPLETED
Conditions: Psoriasis|Psoriatic Arthritis
Interventions: PROCEDURE: lab draws and imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ImmunoTHerapy Adjacent to Cervical CAncer (ITHACA) Study
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer
Interventions: DRUG: Anti-PD-1 antibody balstilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular Access Choice and Outcomes in the Elderly and Very Elderly With End Stage Renal Disease in China
Status: UNKNOWN
Conditions: End Stage Renal Disease
Interventions: PROCEDURE: AVF creation|PROCEDURE: TCC placement|PROCEDURE: AVG creation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aspirin in the Prevention of Collapse in Osteonecrosis of the Hip
Status: UNKNOWN
Conditions: Osteonecrosis of Femoral Head|Osteonecrosis; Aseptic, Idiopathic
Interventions: DRUG: Aspirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions
Status: RECRUITING
Conditions: Pheochromocytoma|Paraganglioma|Inherited Cancer Syndrome|Associated Conditions|Kidney Neoplasms|Bone Cancer|Thyroid Neoplasms|Other Cancer
Interventions: GENETIC: Genetic screening
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Investigation of the Cardioprotective Effect of Early Administration of SGLT2 in Patients Presented With AMI
Status: RECRUITING
Conditions: Myocardial Infarction
Interventions: DRUG: Dapagliflozin 10mg Tab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Comparative Study of Incision Closure Methods for Total Knee Replacement
Status: COMPLETED
Conditions: Total Knee Replacement Closure|Wound Closure
Interventions: DEVICE: Histoacryl Tissue Adhesive|DEVICE: Dermabond|DEVICE: Staples|DEVICE: Monocryl 4-0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic Effects of Atorvastatin vs. Rosuvastatin on Platelet Reactivity
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Atorvastatin|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of BG00012 on Lymphocyte Subsets and Immunoglobulins in Subjects With Relapsing Remitting Multiple Sclerosis (RRMS).
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting|Multiple Sclerosis
Interventions: DRUG: dimethyl fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Goal Nutrition Therapy Guided by Indirect Calorimetry and Nitrogen Balance Among Critically Ill Patients With Acute Kidney Injury (ENGINE Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Critically Ill|Nutrition Disorders|Acute Kidney Injury
Interventions: OTHER: indirect calorimetry and nitrogen balance|OTHER: Indirect calorimetry (Standard care nutrition arm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Novel Sound Changing Principles in Hearing Instruments to Determine Their Application
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Phonak Audéo L2M with Sound Processing Principle 1|DEVICE: Phonak Audéo L2M with Sound Processing Principle 2|DEVICE: Phonak Audéo L2M with Sound Processing Principle 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Integral Attention Program With or Without Palliative Chemotherapy in Advanced Cancer Patients
Status: WITHDRAWN
Conditions: Cancer
Interventions: DRUG: Standard Palliative Chemotherapy|OTHER: Integral Attention Program (PAI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I Study Evaluating the Treatment of Patients With Locally Advanced Pancreatic Cancer With Carbon Ion Radiotherapy: The PHOENIX-01 Trial
Status: WITHDRAWN
Conditions: Locally Advanced Pancreatic Cancer
Interventions: RADIATION: Carbon Ion Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Afatinib Treatment for Patients With EGFR Mutation Positive NSCLC Who Are Age 70 or Older
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|ErbB Receptors
Interventions: DRUG: Afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Occipital Nerve and Sphenopalatine Ganglion Blockade
Status: COMPLETED
Conditions: Migraine
Interventions: PROCEDURE: greater occipital nerve block|PROCEDURE: transnasal sphenopalatine ganglion block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positive Expiratory Pressure With Blow-bottle Device Versus EPAP After Postoperative Cardiac Surgery
Status: COMPLETED
Conditions: Thoracic Surgery
Interventions: OTHER: PEP in a blow-bottle device|OTHER: EPAP|OTHER: conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SARcopenia and Simplified Geriatric Assessment in Lymphoma Patients Undergoing CAR-T Cell Therapy: the FIL_SAR-CAR Project
Status: RECRUITING
Conditions: Non-hodgkin Lymphoma,B Cell
Interventions: OTHER: Chimeric Antigen Receptor T-cells (CAR-T) therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tocilizumab as Add-On Treatment For Residual Positive, Negative, and Cognitive Symptoms of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Tocilizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Nonacog Beta Pegol (N9-GP) in Previously Untreated Patients With Haemophilia B
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia B
Interventions: DRUG: nonacog beta pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of Intervention in Multi-level Hospitals for Acute Traumatic Brain Injury(Metric-TBI)
Status: RECRUITING
Conditions: Traumatic Brain Injury
Interventions: OTHER: Neurological function|OTHER: Mental State, cognitive function, and life quality assessment|OTHER: Peripheral blood test|OTHER: Hematoma test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Examination of the Efficacy of Preventive Antibiotic Treatment During the Puerperium Among Pregnant Women With Recurrent Urinary Tract Infections
Status: COMPLETED
Conditions: Pregnancy Complications
Interventions: DRUG: Preventive antibiotic treatment- NITROFURANTOIN|DRUG: Preventive antibiotic treatment- CEPHALEXIN|DRUG: PREVENTIVE TREATMENT- AMOXICILLIN|DRUG: PREVENTIVE TREATMENT- AMOXICILLIN AND CLAVULANATE POTASSIUM|DRUG: PREVENTIVE TREATMENT- CEFUROXIME|DRUG: PREVENTIVE TREATMENT SULFAMETHOXAZOLE AND TRIMETHOPRIM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diphenhydramine Ointment for Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DRUG: Diphenhydramine 5%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: VPD-737 for Treatment of Chronic Pruritus
Status: COMPLETED
Conditions: Chronic Pruritus
Interventions: DRUG: VPD-737|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: At-Home Automated External Defibrillator (AED) Training Study
Status: COMPLETED
Conditions: Myocardial Infarction|Heart Arrest|Chest Pain|Congestive Heart Failure|Angina, Unstable
Interventions: BEHAVIORAL: Group I: Video training|BEHAVIORAL: Group II: Video training + enhanced self-efficacy (SE)|BEHAVIORAL: Group III: In-person training + enhanced SE|BEHAVIORAL: Group IV: In-person training + enhanced SE + support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Role of Combined Therapy of Propranolol and Gabapentin in Paroxysmal Sympathetic Hyperactivity in Traumatic Brain Injury
Status: RECRUITING
Conditions: Traumatic Brain Injury
Interventions: DRUG: Propranolol , gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic, Safety, and Tolerability Study of Risperidone ISM® at Different Dose Strengths
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Risperidone ISM 50 mg|DRUG: Risperidone ISM 75 mg|DRUG: Risperidone ISM 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose of PF-06835919 Escalation Study in Healthy Adult Subjects
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DRUG: PF-06835919|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Intensive Inpatient Psychotherapy Treatment for Severely and Early Traumatized Children (MOSES)
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Intensive in-patient psychotherapy treatment|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Nadofaragene Firadenovec vs. Observation in Participants With Intermediate Risk Non-Muscle Invasive Bladder Cancer
Status: NOT_YET_RECRUITING
Conditions: Intermediate Risk Non-Muscle Invasive Bladder Cancer
Interventions: DRUG: Nadofaragene Firadenovec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Activity in People With Chronic Neuropathic Pain and Spinal Cord Injury
Status: UNKNOWN
Conditions: Neuropathic Pain|Spinal Cord Injury
Interventions: OTHER: Neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Long-course Chemoradiation Plus PD-1 Blockade for Mid-low Locally Advanced Rectal Cancer
Status: RECRUITING
Conditions: Locally Advanced Rectal Cancer
Interventions: COMBINATION_PRODUCT: Long-course chemoradiation, with or without Tislelizumab (PD-1 inhibitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects a Rehabilitation Program in Patients With Left Ventricular Dysfunction After Coronary Artery Bypass Grafting
Status: UNKNOWN
Conditions: Disorder; Heart, Functional, Postoperative, Cardiac Surgery
Interventions: OTHER: Walking exercise|OTHER: Stationary cycling exercise|OTHER: Neuromuscular electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A First in Human Clinical Trial to Evaluate the Safety and Effectiveness of the STREAMLINE SURGICAL SYSTEM in Patients With Open-Angle Glaucoma
Status: COMPLETED
Conditions: Open Angle Glaucoma
Interventions: DEVICE: Streamline Surgical System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retinal Blood Flow and Autoregulation
Status: RECRUITING
Conditions: Glaucoma
Interventions: DIAGNOSTIC_TEST: Indocyanine Green Angiography|BIOLOGICAL: Isocapnic Oxygen|DIAGNOSTIC_TEST: Ocular Imaging with Optical Coherence Tomography (OCT) and Adaptive Optics (AO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Early-customized Low Glycaemic-index (GI) Diet Prevents LGA Babies in Overweight/Obese Pregnant Women
Status: UNKNOWN
Conditions: Maternal Obesity Complicating Pregnancy, Birth,or Puerperium|Gestational Diabetes Mellitus|Birthweight|Large for Gestational Age (LGA)|Caloric Restriction|Lifestyle Intervention
Interventions: BEHAVIORAL: Low-glycemic index group|OTHER: Standard Care Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Perioperative Electroacupuncture for Gastric Cancer Patients After Gastrectomy
Status: UNKNOWN
Conditions: Acupuncture|Gastrointestinal Function
Interventions: PROCEDURE: Electroacupuncture|PROCEDURE: Sham electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prosthesis Versus Active Exercise Program in Patients With Glenohumeral Osteoarthritis
Status: RECRUITING
Conditions: Glenohumeral Osteoarthritis
Interventions: PROCEDURE: TSA-group|OTHER: Exercise-group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glycaemic Index (GI) Evaluation of Carbohydrate-based Food With Functional Ingredients Derived From Food Sources
Status: COMPLETED
Conditions: Postprandial Hyperglycemia
Interventions: DIETARY_SUPPLEMENT: Anthocyanin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Low Frequency Ultrasound for Osteoarthritis Healing and Rehabilitation
Status: RECRUITING
Conditions: Osteo Arthritis Knee|Age Related Osteoporosis|Pain|Knee Joint Contracture
Interventions: DEVICE: Low Frequency Ultrasound Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Duloxetine in Conjunction With Tramadol for Chronic Cancer Pain
Status: UNKNOWN
Conditions: Cancer Pain
Interventions: DRUG: Duloxetine 30 mg|DRUG: Tramadol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, and Efficacy of BxC-I17e Repeated-dose SC Injection in Patients With Moderate to Severe Atopic Dermatitis
Status: WITHDRAWN
Conditions: Atopic Dermatitis
Interventions: DRUG: BxC-I17e|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Open Preperitoneal Surgery With Polysoft Mesh Versus a Classic Open Surgery With Light Weight Mesh
Status: COMPLETED
Conditions: Hernia, Inguinal
Interventions: DEVICE: Polysoft Mesh|DEVICE: Light Weight Mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Assessment of Central Medial Thalamus Stimulation Using Transcranial Focused Ultrasound
Status: RECRUITING
Conditions: Healthy
Interventions: DEVICE: Transcranial Focused Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: End-on Versus Parallel Radiofrequency Lesioning for Neurotomy of the Cervical Medial Branch Nerves
Status: RECRUITING
Conditions: Neck Pain|Zygapophyseal Joint Arthritis
Interventions: PROCEDURE: Radiofrequency neurotomy (RFN) of Cervical Medial Branch Nerves (CMBNn) with parallel lesioning|PROCEDURE: Radiofrequency neurotomy (RFN) of Cervical Medial Branch Nerves (CMBNn) with end-on lesioning with multitined trident cannulae
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Social Emotion Regulation Intervention in MS
Status: UNKNOWN
Conditions: Multiple Sclerosis|Emotional Disturbances
Interventions: BEHAVIORAL: Social Emotion Regulation Strategy Development|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Solriamfetol's Effect on Cognitive Health in Apnea Participants During a Randomized Placebo-controlled Study
Status: COMPLETED
Conditions: Excessive Daytime Sleepiness|Obstructive Sleep Apnea|Impaired Cognitive Function
Interventions: DRUG: Solriamfetol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intralesional Diode Laser Treatment of Fistulas in Hidradenitis Suppurativa
Status: RECRUITING
Conditions: Hidradenitis Suppurativa
Interventions: PROCEDURE: 1470 nm intra-lesional diode laser treatment of right HS tunnel|PROCEDURE: 1470 nm intra-lesional diode laser treatment of left HS tunnel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Microneedles With Topical Botulinum Toxin for Treatment of Palmar Hyperhidrosis
Status: COMPLETED
Conditions: Hyperhidrosis
Interventions: DEVICE: Microneedle|DEVICE: Sham Microneedle|DRUG: Botulinum Toxin Type A|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Pregabalin Improve Symptoms of Anxiety in Patients With Epilepsy? A Comparison With Sertraline
Status: WITHDRAWN
Conditions: Epilepsy|Anxiety
Interventions: DRUG: Pregabalin-Lyrica|DRUG: Sertraline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: THR-18's Pharmacokinetics and Pharmacodynamics in Subjects With Acute Ischemic Stroke Treated With tPA
Status: COMPLETED
Conditions: Stroke, Acute
Interventions: DRUG: THR-18|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial Comparing Nightmare Deconstruction and Reprocessing vs. NightWare Wristband
Status: RECRUITING
Conditions: Nightmares Associated With Chronic Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: Nightmare Deconstruction and Reprocessing|DEVICE: NightWare
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Olutasidenib and Temozolomide in HGG
Status: NOT_YET_RECRUITING
Conditions: High Grade Glioma|Astrocytoma|Astrocytoma, Grade III|Astrocytoma, Grade IV|Diffuse Intrinsic Pontine Glioma|WHO Grade III Glioma|WHO Grade IV Glioma|Metastatic Brain Tumor|Diffuse Midline Glioma, H3 K27M-Mutant|Thalamus Tumor|Spinal Tumor|IDH1 Mutation|IDH1 R132|IDH1 R132C|IDH1 R132H|IDH1 R132S|IDH1 R132G|IDH1 R132L|Oligodendroglioma
Interventions: DRUG: Olutasidenib + TMZ
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamics, Safety/Tolerability and Efficacy of Topical Omiganan in Patients With uVIN
Status: COMPLETED
Conditions: Usual Type Vulval Intraepithelial Neoplasia (uVIN)
Interventions: DRUG: Omiganan (CLS001) topical gel|DRUG: Vehicle topical gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reliability, Validity, and Cross-cultural Adaptation of the Turkish Version of the Victorian Institute of Sports Assessment for Gluteal Tendinopathy (VISA-G) Questionnaire
Status: COMPLETED
Conditions: Greater Trochanteric Pain Syndrome of Both Lower Limbs|Gluteal Tendinitis
Interventions: OTHER: Survey study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The ENROUTE Transcarotid Neuroprotection System (ENROUTE Transcarotid NPS) DW-MRI Study
Status: COMPLETED
Conditions: Carotid Stenosis|Carotid Artery Diseases|Carotid Atherosclerosis|Carotid Artery Plaque
Interventions: PROCEDURE: Transcarotid revascularization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PC4PrEP: Integrating PrEP Into Primary Care
Status: COMPLETED
Conditions: Human Immunodeficiency Virus Transmission
Interventions: OTHER: PC4PrEP- Intervention Clinics|OTHER: Standard of Care Clinics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Carbonated Beverage Consumption in pH and Bacterial Proliferation
Status: COMPLETED
Conditions: pH|Saliva|Dental Plaque
Interventions: DRUG: Natural Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Delivery Room CPAP in Extremely Low Birth Weight Infants
Status: COMPLETED
Conditions: Infant, Newborn|Infant, Low Birth Weight|Infant, Small for Gestational Age|Infant, Premature|Bronchopulmonary Dysplasia|Continuous Positive Airway Pressure
Interventions: DEVICE: CPAP/PEEP|DEVICE: Standard management practices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Single-dose Bioavailability Study of Different CoQ10 Formulations
Status: COMPLETED
Conditions: Bioavailability of Coenzyme Q10
Interventions: DIETARY_SUPPLEMENT: Single dose intervention with Standard product (SP)|DIETARY_SUPPLEMENT: Single dose intervention with Investigational product (IP1)|DIETARY_SUPPLEMENT: Single dose intervention with Investigational product (IP2)|DIETARY_SUPPLEMENT: Single dose intervention with Investigational product (IP3)|DIETARY_SUPPLEMENT: Single dose intervention with Investigational product (IP4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intra-lesional Nivolumab Therapy for Limited Cutaneous Kaposi Sarcoma
Status: COMPLETED
Conditions: Kaposi Sarcoma|HIV/AIDS|Immunosuppression
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Nightmare Augmented Protocol for Treatment of Nightmares in Veterans With PTSD
Status: TERMINATED
Conditions: PTSD
Interventions: BEHAVIORAL: NAP|BEHAVIORAL: CPT|BEHAVIORAL: ERRT|BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Nd-YAG Laser Versus Epidermal Growth Factor For Myogenic Tempromandibular Disorder.
Status: COMPLETED
Conditions: Temporomandibular Joint Disorders
Interventions: DEVICE: Nd-YAG Fotona|DRUG: Epidermal Growth Factor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of P-cresyl Sulfate Producer Phenotype by Oral Tyrosine Challenge Test: Interactions Among Diet, Gut Microbiota, and Host Genome
Status: UNKNOWN
Conditions: Chronic Kidney Diseases|Healthy
Interventions: DIETARY_SUPPLEMENT: Tyrosine, brand name: myprotein
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ultrasound Measure of Gastric Volume in Diabetic and Non Diabetic Patients Before General Anesthesia
Status: COMPLETED
Conditions: Diabetes
Interventions: PROCEDURE: Ultrasonic measurement of antral area
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Effect of Helpers Program On-line Training on Smoking Relapse and Social Networks
Status: ENROLLING_BY_INVITATION
Conditions: Smoking|Cigarette Smoking
Interventions: BEHAVIORAL: Helpers Stay Quit Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Induction and Maintenance Study of BMS-936557 in Patients With Moderate to Severely Active Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Placebo|DRUG: Placebo|DRUG: BMS-936557 (Anti-IP-10 Antibody)|DRUG: BMS-936557 (Anti-IP-10 Antibody)|DRUG: BMS-936557 (Anti-IP-10 Antibody)|DRUG: BMS-936557 (Anti-IP-10 Antibody)|DRUG: BMS-936557 (Anti-IP-10 Antibody)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Pioglitazone Combined With Metformin on Metabolic Syndrome in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Pioglitazone and Metformin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brazilian Lung Immunotherapy Study
Status: COMPLETED
Conditions: Lung Neoplasm
Interventions: DRUG: Alectinib|DRUG: Pembrolizumab|DRUG: Nivolumab|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Educational Video to Improve Patient Comprehension of Midurethral Sling
Status: UNKNOWN
Conditions: Stress Urinary Incontinence|Knowledge, Attitudes, Practice
Interventions: OTHER: Educational video|OTHER: Educational leaflet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Immunosuppressant Regimens for Living Fetuses Study
Status: UNKNOWN
Conditions: Undifferentiated Connective Tissue Disease|Recurrent Pregnancy Loss
Interventions: DRUG: Prednisone|DRUG: Hydroxychloroquine|DRUG: Aspirin|DRUG: low molecular weight heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Myeloma in Patients <= 65 Years Old With Response >= 50% After HSC Autotransplant by Allogenic Transplant Genoidentical or Phenoidentical After Reduced Intensity Conditioning
Status: COMPLETED
Conditions: Myeloma
Interventions: DRUG: reduced intensity conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Entertaining Action-video Games Enhance Dynamic Visual Function and Improve Balance? A Randomized Controlled Trial.
Status: COMPLETED
Conditions: Vision, Balance and Falls in Older Adults
Interventions: BEHAVIORAL: Slow-paced action video game|BEHAVIORAL: Fast-paced action video game|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Ulinastatin for Reducing Radiation-Induced Oral Mucositis in Nasopharyngeal Carcinoma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Oral Mucositis (Ulcerative) Due to Radiation
Interventions: DRUG: Cisplatin|RADIATION: Intensity Modulated Radiation Therapy|DRUG: Ulinastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the No-reflow in Diabetic Patients Treated With Primary Percutaneous Coronary Intervention (PCI)
Status: UNKNOWN
Conditions: No-Reflow Phenomenon
Interventions: DIAGNOSTIC_TEST: 1- LDL-C (low-density lipoprotein cholesterol)| and HDL-C(high-density lipoprotein cholesterol) Ratio. 2- Glycemia will be assessed : RBS ( random blood sugar ) . 3- S
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Provigil (Modafinil) Study by Taiwan Biotech Co.
Status: COMPLETED
Conditions: Narcolepsy|Cataplexy|Sleep Disorders|Hypersomnolence|Excessive Sleepiness
Interventions: DRUG: Modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phrenic Nerve Infiltration in Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Bupivacain|OTHER: Placebo (physiological saline serum infiltration)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating ABX-EGF in Patients With Metastatic ColorectalCarcinoma
Status: COMPLETED
Conditions: Colorectal Cancer|Carcinoma
Interventions: DRUG: ABX-EGF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DHA Supplementation for Lactating Mothers
Status: COMPLETED
Conditions: Docosohexaenoic Acid Supplementation of Mothers to
Interventions: DRUG: Expecta 200 mg|DRUG: Expecta 1 gram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study About Safety and Efficacy of Coenzyme Q10 in Progressive Supranuclear Palsy
Status: COMPLETED
Conditions: Progressive Supranuclear Palsy
Interventions: DRUG: Coenzyme Q10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Anlotinib With STUPP Regimen for Patients With Newly Diagnosed Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: Drug is Anlotinib.|DRUG: Drug is Temozolomide Capsule.|RADIATION: Radiotherapy was initiated 4 to 6 weeks postoperatively.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequencing Treatments for Mothers With ADHD and Their At - Risk Children
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Vyvanse (lisdexamphetamine)|BEHAVIORAL: Behavior Parent Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its Safety
Status: COMPLETED
Conditions: Resistant Hypertension
Interventions: DRUG: Aprocitentan 12.5 mg|DRUG: Aprocitentan 25 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Celecoxib With Chemotherapy in Localized, Muscle-Invasive Bladder Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: Celecoxib|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Self-Titration and Predictors for Blood Pressure Control in Patients With Hypertension
Status: UNKNOWN
Conditions: Primary Hypertension
Interventions: BEHAVIORAL: Self-titration strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Durvalumab and Tremelimumab With Gemcitabine or Gemcitabine/Cisplatin Compared to Gemcitabine/Cisplatin in CCA Patients
Status: COMPLETED
Conditions: Cholangiocarcinoma|Gall Bladder Carcinoma|Cholangiocarcinoma Non-resectable|Gallbladder Carcinoma Non-Resectable
Interventions: BIOLOGICAL: Durvalumab|DRUG: Gemcitabine|DRUG: Cisplatin|BIOLOGICAL: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: tDCS and Speech Therapy to Improve Aphasia
Status: UNKNOWN
Conditions: Aphasia, Global|Stroke|Transcranial Direct Current Stimulation|Speech Therapy
Interventions: PROCEDURE: tDCS + speech therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Treprostinil in Ischemia and Reperfusion Injury in Adult Orthotopic Liver Transplantation
Status: COMPLETED
Conditions: Ischemia Reperfusion Injury
Interventions: DRUG: Treprostinil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of a Natural Health Product in Reducing Cholesterol and Triglyceride Levels.
Status: COMPLETED
Conditions: LDL Cholesterol|Triglycerides
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Investigational Product 1|DIETARY_SUPPLEMENT: Investigational Product 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of AL-4943A Ophthalmic Solution in Patients With Allergic Conjunctivitis Using the Conjunctival Allergen Challenge (CAC) Model
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: AL-4943A ophthalmic solution|DRUG: AL-4943A vehicle|DRUG: Olopatadine hydrochloride ophthalmic solution, 0.2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Lung Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: etoposide|DRUG: paclitaxel|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: pDIFFIR: Geriatric Periprosthetic DIstal Femur: FIxation Versus Replacement
Status: RECRUITING
Conditions: Distal Femur Fracture|Periprosthetic Fracture Around Prosthetic Joint Implant Knee|Knee Fracture
Interventions: PROCEDURE: Distal Femur Replacement|PROCEDURE: Surgical fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Full-time Bangerter Filters Versus Part-time Daily Patching for Moderate Amblyopia in Children
Status: COMPLETED
Conditions: Amblyopia
Interventions: DEVICE: Bangerter filters|DEVICE: Patching|PROCEDURE: Near activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotine Treatment for Pulmonary Sarcoidosis: A Clinical Trial Pilot Study
Status: COMPLETED
Conditions: Sarcoidosis
Interventions: DRUG: Habitrol|DRUG: Placebo to Habitrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Safety, Tolerance and Pharmacokinetic Characteristics of Single Administration of HRS-5635 Injection in Chinese Healthy Subjects and the Safety, Tolerance, Pharmacokinetics and Antiviral Effect of Multiple Administration in Patients With Chronic Hepatitis B
Status: RECRUITING
Conditions: Chronic Hepatitis B
Interventions: DRUG: HRS-5635|DRUG: HRS-5635|DRUG: HRS-5635|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combined Antioxidant Therapy on Oxidative Stress, Mitochondrial Dysfunction Markers in Diabetic Retinopathy
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DRUG: Combined antioxidant therapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immune Response to Recombinant Live-Attenuated Influenza H2N2 Virus Vaccine
Status: COMPLETED
Conditions: Influenza|Virus Diseases
Interventions: BIOLOGICAL: H2N2 1960 AA ca recombinant vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Optimization of the Treatment of Dry Eye Disease Caused by Meibomian Gland Dysfunction
Status: COMPLETED
Conditions: Dry Eye Syndromes|Meibomian Gland Dysfunction
Interventions: DEVICE: Blephasteam|DEVICE: THERA°PEARL Eye Mask|DRUG: Hylo-comod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise and Neurocognition in Adults Relative to ApoE Genotype
Status: RECRUITING
Conditions: Exercise Training|Neurocognitive Function|Aging
Interventions: BEHAVIORAL: Integrated Intervention Group (IIG)|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A First-in-human Study of a Novel Recombinant Humanized Anti-interleukin-6 Receptor Monoclonal Antibody
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: VDJ001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Tezepelumab on Airway Inflammation in Adults With Uncontrolled Asthma (CASCADE)
Status: COMPLETED
Conditions: Asthma|Bronchial Diseases|Respiratory Tract Diseases|Lung Diseases, Obstructive|Lung Diseases|Respiratory Hypersensitivity|Hypersensitivity, Immediate|Hypersensitivity|Immune System Diseases
Interventions: BIOLOGICAL: Tezepelumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT