pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Community Health Worker Training to Reduce Depression and Substance Use Stigma in TB/HIV Care in South Africa
Status: COMPLETED
Conditions: Substance-Related Disorders|Mental Disorder|Social Stigma|Depression|Treatment Adherence and Compliance|Health Care Utilization|Attitude of Health Personnel|Hiv|Tuberculosis|Mental Health Disorder|Community Health Workers|Health Care Delivery
Interventions: BEHAVIORAL: Siyakhana CHW Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Study of a Selective 5-ht6 Receptor Antagonist, HEC30654AcOH,in Healthy Subjects
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: HEC30654AcOH capsule|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Octreotide on the Colonic Motility in Pediatric Patients
Status: COMPLETED
Conditions: Colonic Motility Index|Constipation
Interventions: DRUG: Octreotide|DRUG: Bisacodyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Online Platform for Self-service of Patients With Chronic Cardiovascular Diseases
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: OTHER: Group A: online real-time home based exercise using the online platform|OTHER: Group B: supervised community based exercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Administration of Intravenous and Topical Tranexamic Acid in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Degenerative Arthritis
Interventions: DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Observational Study to Evaluate, Under Real-world Practice Conditions, the Safety and Effectiveness of Regorafenib in Patients Diagnosed With Unresectable Hepatocellular Carcinoma (uHCC)
Status: COMPLETED
Conditions: Liver Neoplasms
Interventions: DRUG: Regorafenib (Stivarga, BAY73-4506)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Gut Micribiota Disruption on the Immune Response After Open Heart Surgery
Status: UNKNOWN
Conditions: Systemic Inflammatory Response Syndrome|Postoperative Shock|Coronary Artery Disease|Extracorporeal Circulation; Complications
Interventions: DRUG: Vancomycin Oral|DRUG: Metronidazole Oral|DRUG: Ciprofloxacin Pill|DRUG: Fluconazole Oral Product|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetic of Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection
Status: UNKNOWN
Conditions: Systemic Juvenile Idiopathic Arthritis|Periodic Fever Syndrome
Interventions: DRUG: SSGJ-613|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Open-Labelled Trial of Intravitreal Ganciclovir Salvage Therapy for AIDS Patients With Active CMV Retinitis Who Are Intolerant of Systemic Therapy
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Tumour Response in Cancer Patients With Advanced Hepatocellular Carcinoma (Liver Cancer) With AMT2003
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: AMT2003
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetic Study of HIV Prophylaxis Using Antiretroviral Intravaginal Rings in Healthy Women
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV) Prophylaxis
Interventions: DRUG: TDF IVR|DRUG: TDF-FTC IVR|DRUG: TDF-FTC-MVC IVR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Integration of Social Art Activities and Qigong for Older People in Nursing Home in Indonesia
Status: COMPLETED
Conditions: Well-being|Depressive Symptoms
Interventions: BEHAVIORAL: Qigong and art activities|BEHAVIORAL: Art activities|BEHAVIORAL: Qigong|BEHAVIORAL: Daily activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The MEC90 of Epidural Ropivacaine Blunting Hemodynamic Changes to Pneumoperitoneum
Status: UNKNOWN
Conditions: Laparoscopic Gastrectomy
Interventions: DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Long-Term Follow-Up Gene Therapy Study for Achromatopsia CNGB3 and CNGA3
Status: COMPLETED
Conditions: Achromatopsia
Interventions: BIOLOGICAL: either AAV - CNGB3 or AAV - CNGA3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Vitamin D Status In Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: ergocalciferol (vitamin D2)|DEVICE: Sperti Del Sol Lamp|DRUG: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MEK162 and RAF265 in Adult Patients With Advanced Solid Tumors Harboring RAS or BRAFV600E Mutations
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: MEK162 + RAF265
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing Live Donor Kidney Transplantation Through Video-based Education and Mobile Communication
Status: ACTIVE_NOT_RECRUITING
Conditions: End-stage Renal Disease|Chronic Kidney Diseases
Interventions: BEHAVIORAL: Kidney donation and transplant information made easy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: DBS and SCS Therapy Improve Motor Function in Multiple System Atrophy With Predominant Parkinsonism
Status: UNKNOWN
Conditions: Multiple System Atrophy, Parkinson Variant (Disorder)
Interventions: PROCEDURE: Bilateral STN-DBS and T10-T12 SCS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluatıon of the Effıcıency of Stress Management Traınıng Applıed to Nursıng Students (Happy Nursıng Student)
Status: COMPLETED
Conditions: Stress
Interventions: BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Smart Technology Facilitated Venous Thromboembolism Prophylaxis Based on Bundled Evidence-based Prevention Strategies
Status: NOT_YET_RECRUITING
Conditions: Venous Thromboembolism|Clinical Decision Support Systems|Digital Health
Interventions: OTHER: Application of the modified DeVTEcare system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intra-Cardiac Echocardiography Guided Cardioversion(ICE-CHIP) Study
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Intra-Cardiac Echocardiography guided Cardioversion|DEVICE: Intracardiac Echo|DEVICE: ICE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-Based Weight Management for Individuals With Mental Illness
Status: COMPLETED
Conditions: Mental Disorders|Schizophrenia|Affective Disorders, Psychotic|Overweight|Obesity
Interventions: BEHAVIORAL: eWellness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Effect of Food on the Pharmacokinetics of Palovarotene and the Effect of Palovarotene on the Pharmacokinetics of the CYP3A4 Substrate Midazolam in Two Cohorts of Healthy Adult Subjects
Status: COMPLETED
Conditions: Fibrodysplasia Ossificans Progressiva
Interventions: DRUG: Palovarotene|DRUG: midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib With Bendamustine / Rituximab Followed by Cytarabine / Rituximab for Untreated Mantle Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Bendamustine|DRUG: Rituximab|DRUG: Acalabrutinib|DRUG: Cytarabine|PROCEDURE: Leukapheresis|PROCEDURE: Peripheral blood|PROCEDURE: Oral rinse|PROCEDURE: Bone marrow collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promising ROd-cone DYstrophy Gene therapY
Status: RECRUITING
Conditions: Retinitis Pigmentosa
Interventions: DRUG: SPVN06
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)
Status: NOT_YET_RECRUITING
Conditions: Brain Concussion|Brain Trauma|Attention Concentration Difficulty|Brain Injuries|Brain Injuries, Traumatic|Neurocognitive Dysfunction|Attention Impaired|Memory Impairment|Mild Traumatic Brain Injury|Mild Cognitive Impairment|Post Concussive Symptoms
Interventions: COMBINATION_PRODUCT: Active tDCS and Cognitive Training Intervention|COMBINATION_PRODUCT: Sham tDCS and Cognitive Training Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: INFUSE® Bone Graft/ PEEK Interbody Spacer/ Anterior Cervical Plate Pivotal Clinical Trial
Status: COMPLETED
Conditions: Degenerative Disc Disease
Interventions: DEVICE: INFUSE® Bone Graft/PEEK Spacer/Anterior Cervical Plate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Forced-dose Titration of SPD489 in Adults With Binge Eating Disorder
Status: COMPLETED
Conditions: Binge Eating Disorder
Interventions: DRUG: lisdexamfetamine dimesylate (SPD489)|DRUG: lisdexamfetamine dimesylate (SPD489)|DRUG: lisdexamfetamine dimesylate (SPD489)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aggressive Driving and Road Rage: A Driving Simulation Experiment.
Status: RECRUITING
Conditions: Aggression
Interventions: BEHAVIORAL: Videos|BEHAVIORAL: Bumper stickers|BEHAVIORAL: Alcohol-related cues|BEHAVIORAL: Music|BEHAVIORAL: Roadside vegetation|BEHAVIORAL: Video game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Surgical Outcome and Multimodal Monitoring - SOMM
Status: COMPLETED
Conditions: Complications
Interventions: DEVICE: LiDCO Rapid|DEVICE: BIS-Bispectral Index Monitor|DEVICE: INVOS-Cerebral Oxygenation Monitor|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of a Combined Diet and Mindfulness Program on Weight Loss in Breast Cancer Survivors
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Weight Loss
Interventions: BEHAVIORAL: Dietary program|BEHAVIORAL: Exercise program|BEHAVIORAL: Mindfulness program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Identifying Risks of COVID-19 Outbreaks in Work Settings and the Implications for Control Measures
Status: COMPLETED
Conditions: Intention to Get SARS-CoV-2 Vaccination|Intention to Get SARS-CoV-2 Antibody Test
Interventions: BEHAVIORAL: Theory of planned behaviours (TPB) based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CBD for Knee Osteoarthritis
Status: RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Cannabidiol (CBD) Extract|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sentinel Lymph Node Biopsy Versus Lymphadenectomy in Endometrial Cancer
Status: COMPLETED
Conditions: Early Stage Endometrial Cancer|Sentinel Lymph Nodes|Lymphadenectomy
Interventions: PROCEDURE: Sentinel lymph node mapping and biopsy|PROCEDURE: Lymphadenectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Outpatient Physical Therapy Intervention in Subjects With Parkinson's Disease Currently Using APOKYN®
Status: TERMINATED
Conditions: Parkinson's Disease|Motor Symptoms
Interventions: DRUG: APOKYN|BEHAVIORAL: Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MSC for Treatment of Interstitial Lung Disease After Allo-HSCT
Status: UNKNOWN
Conditions: Lung Diseases, Interstitial|Hematopoietic Stem Cell Transplantation|Bronchiolitis Obliterans
Interventions: BIOLOGICAL: MSCs|DRUG: AZM|DRUG: Glucocorticoid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Emergency Department Smartphone Otoscope Study (PED-Oto)
Status: COMPLETED
Conditions: Acute Otitis Media|Acute Otitis Externa
Interventions: DEVICE: Smartphone otoscope|DEVICE: Conventional otoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Non-Pharmacological Method for Enhancing Sleep in PTSD
Status: COMPLETED
Conditions: PTSD|Sleep Problems
Interventions: DEVICE: PTSD wavelength-1 bright light|DEVICE: PTSD wavelength-2 bright light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Aerobic, Resistance, and Combined Training in Overweight/Obese Hypertensive Adults
Status: COMPLETED
Conditions: Obese|Hypertension
Interventions: OTHER: Aerobic exercise training Group|OTHER: Resistance Exercise Training Group|OTHER: Combined Exercise Training Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Golimumab in Participants With Active Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Placebo|DRUG: Golimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of FURESTEM-AD Inj. in Patients With Moderate to Severe Chronic Atopic Dermatitis(AD)
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: FURESTEM-AD Inj.|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Plant Stanols as Ester on Change in Blood Cholesterol Level
Status: COMPLETED
Conditions: LDL-cholesterol Level 130-159mg/dL
Interventions: OTHER: Yoghurt drink containing plant stanol as esters|OTHER: Yoghurt drink without plant stanol as esters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Foot Bath on Pain, Anxiety, Sleep and Comfort Level
Status: ACTIVE_NOT_RECRUITING
Conditions: Laparoscopic Cholecystectomy
Interventions: OTHER: foot bath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Indole-3-Carbinol and Silibinin
Status: COMPLETED
Conditions: Smoking
Interventions: DRUG: Indole-3-Carbinol|DRUG: Silibinin|DRUG: Silibin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: [68Ga]DOTATATE-PET/MRI in Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: [68Ga]DOTATATE-PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Restrictive Fluid and Vasopressin During Surgery of Burn Patients
Status: UNKNOWN
Conditions: Burn Surgery
Interventions: DRUG: Vasopressin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Düsseldorf Bread Study
Status: COMPLETED
Conditions: Body Weight
Interventions: OTHER: carbohydrate reduced bread|OTHER: carbohydrate rich bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase III Study of the Efficacy and Safety of Remimazolam Compared to Placebo and Midazolam in Colonoscopy Patients
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: Remimazolam|DRUG: Midazolam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Detection of Paracetamol Concentration in Blood-, Saline- and Urine Samples - a Validation Study for a Novel Technique
Status: COMPLETED
Conditions: Drug Mechanism|Healthy
Interventions: DRUG: Paracetamol|DIAGNOSTIC_TEST: Paracetamol concentration measurements and lipidomic assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Added Value of Cognitive Behavioural Therapy for Insomnia in Persons With Knee Osteoarthritis
Status: RECRUITING
Conditions: Osteoarthritis, Knee|Insomnia
Interventions: BEHAVIORAL: Cognitive behavioral therapy for insomnia (CBT-I) integrated in best-evidence usual care (CBTi-UC)|BEHAVIORAL: Best-evidence usual care (UC) plus information sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Concomitant Administration of BMS-986195 on Methotrexate, Caffeine, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: BMS-986195|DRUG: Methotrexate|DRUG: Leucovorin|DRUG: Caffeine|DRUG: Montelukast|DRUG: Flurbiprofen|DRUG: Omeprazole|DRUG: Midazolam|DRUG: Digoxin|DRUG: Pravastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prospective Randomized Evaluation of Decompressive Ipsilateral Craniectomy for Traumatic Acute Epidural Hematoma
Status: RECRUITING
Conditions: Epidural Hematoma|Brain Herniation|Decompressive Craniectomy|Craniotomy
Interventions: PROCEDURE: Decompressive Craniectomy|PROCEDURE: Craniotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention Targeting Parental Reminiscing and Its Effects on Preschoolers' Memory and Metacognition
Status: UNKNOWN
Conditions: Child Development|Parent-Child Relations
Interventions: BEHAVIORAL: Intervention targeting parental reminiscing style
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Dose-response of Ketamine in Patient Controlled Analgesia in Orthopaedic Surgery Patients
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Oxycodone|DRUG: S-Ketamine 0.25|DRUG: S-Ketamine 0.5|DRUG: S-Ketamine 0.75
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Substrate Modification in Stable Ventricular Tachycardia in Addition to Implantable Cardioverter Defibrillator (ICD) Therapy
Status: COMPLETED
Conditions: Ventricular Tachycardia|Coronary Artery Disease|Left Ventricular Dysfunction
Interventions: PROCEDURE: Substrate modification|PROCEDURE: VT ablation|PROCEDURE: ICD Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ExPECT: Extraperitoneal End Colostomy Trial
Status: COMPLETED
Conditions: Colostomy Stoma|Cancer of Colon|Surgery|Quality of Life
Interventions: PROCEDURE: Extra-peritoneal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO)
Status: RECRUITING
Conditions: Congenital Diaphragmatic Hernias
Interventions: DEVICE: Fetoscopic Endoluminal Tracheal Occlusion (FETO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GSL Synthetase Inhibitor Plus Immune Checkpoint Inhibitor and/or Regorafenib in Previously Treated pMMR/MSS CRC.
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Eliglustat+Immune checkpoint inhibitor+Regorafenib|DRUG: Eliglustat+Immune checkpoint inhibitor|DRUG: Regorafenib+Immune checkpoint inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preemptive Analgesia Following Uterine Artery Embolization
Status: TERMINATED
Conditions: Uterine Fibroids|Uterine Artery Embolization
Interventions: DRUG: pregabalin/celecoxib|DRUG: pregabalin/placebo|DRUG: celecoxib/placebo|DRUG: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Growth of Infants Fed an Amino Acid Infant Formula
Status: COMPLETED
Conditions: Growth
Interventions: OTHER: Amino Acid Formula|OTHER: Amino Acid formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dispervise Ophthalmic Viscoelastic as an Agent to Ensure Watertight Wound Closure After Clear Corneal Cataract Incisions
Status: COMPLETED
Conditions: Cataracts
Interventions: DRUG: Viscoat|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Adverse Events, and How Intravenously (IV) Infused ABBV-969 Moves Through the Bodies of Adult Participants With Metastatic Castration-Resistant Prostate Cancer
Status: RECRUITING
Conditions: Metastatic Castration-Resistant Prostate Cancer
Interventions: DRUG: ABBV-969
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of TQ-F3083 Capsules in Subjects With Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: TQ-F3083 capsule 10 mg|DRUG: TQ-F3083 capsule 20 mg|DRUG: TQ-F3083 blank analog capsule|DRUG: TQ-F3083 blank analog capsule|DRUG: Linagliptin blank analog tablet|DRUG: Linagliptin tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tenofovir Alone Versus Tenofovir With Emtricitabine to Treat Chronic Hepatitis B
Status: TERMINATED
Conditions: Hepatitis B
Interventions: DRUG: Tenofovir & Emtricitabine|DRUG: Tenofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain and Chronic Pancreatitis - Clinical End Experimental Studies
Status: COMPLETED
Conditions: Chronic Pancreatitis
Interventions: DRUG: Pregabalin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Non-Hodgkin's Lymphoma or Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: etoposide|DRUG: ifosfamide|DRUG: topotecan hydrochloride|PROCEDURE: autologous bone marrow transplantation|DRUG: Mesna
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Breast Milk Odor on Feeeding in Preterm Infants
Status: COMPLETED
Conditions: Bottle Feeding|Preterm İnfant
Interventions: OTHER: Milk odor|OTHER: Pacifier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Glycine Supplement for Severe COVID-19
Status: TERMINATED
Conditions: COVID-19|SARS-CoV Infection|SARS (Severe Acute Respiratory Syndrome)|SARS Pneumonia|ARDS, Human|Pneumonia, Viral
Interventions: DIETARY_SUPPLEMENT: Glycine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Oral QPX7831 SAD and MAD in Healthy Adults
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: DRUG: QPX7831|DRUG: placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Sorafenib Added to Standard Primary Therapy in Elderly Patients With Newly Diagnosed AML
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Sorafenib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Selective COX-2 Inhibition on Ulcer Healing
Status: COMPLETED
Conditions: Arthritis|Gastric Ulcer
Interventions: DRUG: celecoxib|DRUG: Dologesics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bovine vs. Human Milk-Based Fortifier Study
Status: COMPLETED
Conditions: Very Low Birth Weight Infant (<1250g)
Interventions: OTHER: Human milk-based fortifier|OTHER: Bovine protein-based fortifier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Widefield Fluorescence and Reflectance Imaging Systems and Oral Tissue Samples in Monitoring Participants at Risk for Developing Oral Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Erythroplakia|Fanconi Anemia|Lichen Planus|Oral Cavity and Lip Precancerous Condition|Oral Cavity Leukoplakia|Oral Neoplasm|Premalignant Lesion|Tobacco Use Disorder
Interventions: OTHER: Cytology Specimen Collection Procedure|PROCEDURE: Diagnostic Microscopy|PROCEDURE: Diagnostic Procedure|PROCEDURE: Fluorescence Imaging|PROCEDURE: Fluorescence Spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of DPP4 Inhibition on Growth Hormone Secretion
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Sitagliptin|DRUG: Pegvisomant|DRUG: Placebo|DRUG: L-NMMA|DRUG: Exendin 9-39
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Long-Term Assessment of Safety and Physical Function With AMG 108 in RA
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: AMG 108|DRUG: AMG 108
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research of Efficient Use of Omeprazole in Combination With Domperidone in Gastroesophageal Reflux Disease of Mild to Moderate Severity
Status: UNKNOWN
Conditions: GERD
Interventions: DRUG: omeprazole+domperidone SR|DRUG: omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dual-task Training in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Diplegia|Hemiplegic Cerebral Palsy|Physical Disability|Participation, Patient|Activity, Motor
Interventions: OTHER: dual-task training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Virtually Supervised Mouthwash and Interdental Brushes
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Colgate Cavity Protection Toothpaste|DRUG: LISTERINE ZERO Alcohol Mouthwash COOL MINT|DRUG: LISTERINE COOL MINT Antiseptic Mouthwash|DEVICE: TePe Original Interdental Brush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: S-Caine™ Peel (Skin Numbing Cream) to Treat Pain During Pulsed Dye Laser (PDL) Therapy in Adults
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: S-Caine™ Peel (lidocaine and tetracaine topical cream 7%/7%)|DRUG: Placebo Peel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evolocumab for PCSK9 Lowering in Early Acute Sepsis (The PLEASe Study)
Status: UNKNOWN
Conditions: Sepsis
Interventions: DRUG: Evolocumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety and Immunogenicity of a Malaria Vaccine Candidate
Status: COMPLETED
Conditions: Prophylaxis Against Plasmodium Falciparum Malaria
Interventions: BIOLOGICAL: Plasmodium falciparum Chimeric Prot. 2.9 - Montanide ISA 720
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: GLP-1 Receptor Agonist Lixisenatide (Morning or Evening) in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Metformin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Lixisenatide (AVE0010)|DRUG: Placebo|DEVICE: Pen auto-injector|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy & Safety of Tralokinumab in Subjects With Asthma Inadequately Controlled on Corticosteroids
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: Tralokinumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diaphragm Ultrasound Vs Transpulmonary Pressure To Set PEEP in ARDS
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Acute Respiratory Failure
Interventions: DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy of a Probiotic for Antibiotic Associated Gastrointestinal Symptoms
Status: RECRUITING
Conditions: Antibiotic-associated Diarrhea
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Placebo-controlled, Randomized Trial of an Adenoviral-vector Based Norovirus Vaccine
Status: COMPLETED
Conditions: Norovirus Gastroenteritis
Interventions: BIOLOGICAL: VXA-G1.1-NN (high dose) Oral Vaccine Tablet|OTHER: VXA Placebo Tablets|BIOLOGICAL: VXA-G1.1-NN (low dose) Oral Vaccine Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Efficacy and Safety of rhTSH as An Adjunctive Diagnostic Tool in Differentiated Thyroid Cancer Patients Who Had Been Thyroidectomized Vs. Patients Who After Thyroid Hormone Withdrawal
Status: COMPLETED
Conditions: Differentiated Thyroid Cancer
Interventions: BIOLOGICAL: rhTSH
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tissue Distribution of F18-FDG Labelled Autologous Bone Marrow Derived Stem Cells in Patients With Type 2 DM
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: Stem cell therapy- SPD artery|OTHER: Stem cell therapy- splenic artery|OTHER: Stem cell therapy-intravenous|OTHER: Normal saline placebo -sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial for the Treatment of Extensively Drug-Resistant Gram-negative Bacilli (OVERCOME)
Status: COMPLETED
Conditions: Pneumonia|Blood Stream Infection
Interventions: DRUG: colistin and meropenem|DRUG: colistin and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Estramustine, Docetaxel and Zoledronate Treatment in Hormone-Refractory Adenocarcinoma of the Prostate
Status: COMPLETED
Conditions: Hormone-Refractory Prostate Cancer
Interventions: DRUG: Zoledronic acid|DRUG: Estramustine|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How Different Forms of The Study Medicine Called Phenytoin Are Taken up Into the Blood in Healthy Adults
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: Phenytoin (Ascoli)|DRUG: Phenytoin (Vega Baja)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Emotional and Non-emotional Regulation in Patients With Emotional Instability and ADHD
Status: UNKNOWN
Conditions: Emotional Instability Personality Disorder (Borderline Personality Disorder)|Attention Deficit Hyperactivity Disorder|Healthy Controls
Interventions: OTHER: fMRI - Stroop task|OTHER: fMRI - MID task|BEHAVIORAL: Stop Signal Task|OTHER: SCID-II|OTHER: SDQ|OTHER: ASRS|OTHER: AQ|OTHER: TAS-20|OTHER: Raven's SPM|OTHER: Reading ability|OTHER: Ishihara's tests for colour deficiency|OTHER: Additional questionnaire|OTHER: Brown-ADD|OTHER: MFQ|OTHER: STAI-T|OTHER: BIS|OTHER: DAWBA|OTHER: STAI-S|OTHER: Sleepiness rating|OTHER: Motivation rating|BEHAVIORAL: FEFA2|OTHER: Structural T1 MRI scan|OTHER: Structural T2 MRI scan|OTHER: DTI MRI scan|OTHER: Resting state MRI scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Distribution of Pressure in the Thorax During Mechanical Ventilation and Its Effects on the Circulation
Status: UNKNOWN
Conditions: Fluid Responsiveness
Interventions: OTHER: ventilatory protocol|OTHER: Elastic band|OTHER: passive leg raising test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of a Nutritional Intervention Focused on Dietary Pattern in the Cardiovascular Risks of Individuals With Bipolar Disorder
Status: NOT_YET_RECRUITING
Conditions: Bipolar Depression
Interventions: BEHAVIORAL: Nutritional intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Canalith Repositioning Procedure for BPPV in Primary Care
Status: COMPLETED
Conditions: Benign Paroxysmal Positional Vertigo
Interventions: PROCEDURE: Canalith repositioning maneuver (CRM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Pathophysiological Mechanisms and Bronchial Response in Occupational Asthma to Wheat Flour and Quaternary Ammonium Compounds During Standardized Bronchial Provocation Tests
Status: TERMINATED
Conditions: Occupational Asthma
Interventions: OTHER: standardized bronchial challenge test (SCL SCL • • GenaSOL ™ GenaSIC ™)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Subantimicrobial Dose Doxycycline for Moderate to Severe and Active Graves' Orbitopathy
Status: COMPLETED
Conditions: Graves Ophthalmopathy|Graves Disease|Eye Diseases|Thyroid Diseases|Endocrine System Diseases|Eye Diseases, Hereditary|Hyperthyroidism|Autoimmune Diseases|Immune System Diseases
Interventions: DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Outcomes Associated With (Holmium Laser Enucleation of the Prostate) HoLEP Procedures
Status: RECRUITING
Conditions: Urologic Diseases|Prostate Obstruction
Interventions: PROCEDURE: HoLEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Left Atrial Enlargement: A Crucial Indicator for Identifying Atrial Fibrillation in Patients With Hypertension
Status: COMPLETED
Conditions: Atrial Fibrillation|Hypertension,Essential|Left Atrial Dilatation
Interventions: DIAGNOSTIC_TEST: CHA2DS2-VASc score, C2HEST score, and left atrial diameter (LAD)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1 TR-701 FA Study of Blood Pressure Response Post Tyramine Challenge
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TR-701 FA with Tyramine|DRUG: Placebo-controlled withTyramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Aprepitant for Postoperative Nausea and Vomiting in Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Aprepitant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment and Management of Post-Stroke Spasticity With Botulinum Toxin-A
Status: COMPLETED
Conditions: Stroke|Muscle Spasticity
Interventions: BEHAVIORAL: Optimal muscle activation therapy|BEHAVIORAL: Standard Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Performance of The Plexur P™ Bone Void Filler Device in Patients Undergoing Iliac Crest Harvesting Procedures
Status: COMPLETED
Conditions: Iliac Crest Harvesting Procedure-Bone Void Filler
Interventions: DEVICE: Plexur-P used as a Bone Void Filler in Iliac Crest Harvesting Procedures
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Bilateral TENS With TOT on Upper Limb Function in Patients With Chronic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Task-orientated training|DEVICE: Transcutaneous electrical nerve stimulation (TENS)|DEVICE: Sham electrical nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Interleukin-2, Interferon-alpha and Bevacizumab in Metastatic Kidney Cancer
Status: UNKNOWN
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Interleukin-2|DRUG: Interferon Alfa-2b|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for Alcohol Use Disorder and Post Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder (PTSD)|Addiction|Alcohol Abuse
Interventions: DRUG: N-Acetylcysteine (NAC) Treatment|BEHAVIORAL: Cognitive Behavioral Therapy (CBT)|DRUG: Inactive Placebo Oral Capsule|OTHER: Functional magnetic resonance imaging (fMRI)|OTHER: Proton magnetic resonance spectroscopy (MRS) Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stimulated Intrauterine Insemination Cycles and Unstimulated Intrauterine Insemination Cycles in Couples With Unexplained Infertility
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: Merional|PROCEDURE: IUI|PROCEDURE: Ovulation detection|DRUG: Choriomon|DEVICE: shepherd catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Transmission-Blocking Vaccine Pfs230D1-EPA/Matrix-M Against Malaria in Adults in Mali
Status: COMPLETED
Conditions: Malaria,Falciparum
Interventions: BIOLOGICAL: Pfs230D1-EPA/Matrix-M Vaccine|BIOLOGICAL: Verorab Rabies Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Observational Program Neo-Penotran® Forte
Status: COMPLETED
Conditions: Vaginal Candidiasis|Bacterial Vaginosis|Trichomonal Vaginitis
Interventions: DRUG: Metronidazole/Miconazole (Neo-Penotran Forte, BAY86-5276)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 12 Week Comparison of 5 Mcg and 10 Mcg of Tiotropium / Respimat, Placebo and Ipratropium MDI in COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: 5 mcg once daily tiotropium inhalation solution delivered by the Respimat inhaler|DEVICE: 10 mcg once daily tiotropium inhalation solution delivered by the Respimat inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Peri-implantitis Implantoplasty Treatment
Status: RECRUITING
Conditions: Peri-Implantitis|Peri-implant Mucositis
Interventions: PROCEDURE: Implantoplasty|PROCEDURE: Open flap debridement alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Moderate to Severe Facial Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Doxycycline 0.6 mg/kg/day|DRUG: Doxycycline 1.2 mg/kg/day|DRUG: Doxycycline 2.4 mg/kg/day|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing JNJ-42756493 In Combination With Dexamethasone in Multiple Myeloma That Came Back After a Period of Improvement
Status: TERMINATED
Conditions: Multiple Myeloma|Relapsed/Refractory
Interventions: DRUG: JNJ-42756493|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed, Cisplatin, and Vitamin B12 in Treating Patients With Mesothelioma of the Chest That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Malignant Mesothelioma
Interventions: DIETARY_SUPPLEMENT: vitamin B12|DRUG: cisplatin|DRUG: pemetrexed disodium|GENETIC: gene expression analysis|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Atypical Neuroleptic Drugs in People With Mental Retardation/Developmental Delay
Status: COMPLETED
Conditions: Mental Retardation|Developmental Delay Disorder
Interventions: DRUG: risperidone|DRUG: clozapine|DRUG: olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Interactions Between Intravenous Cocaine and Acetazolamide or Quinine
Status: COMPLETED
Conditions: Cocaine Use|Pharmacokinetics
Interventions: DRUG: cocaine|DRUG: quinine|DRUG: acetazolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC