pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Smart Linkage-to-HIV Care Via a Smartphone App
Status: COMPLETED
Conditions: HIV Infections|Viral Load|Patient Compliance|Antiretroviral Therapy|Cell Phone
Interventions: OTHER: Smartphone application|DEVICE: Smartphone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oral Treatment for Gynaecological Post-operative Pain With Dexketoprofen Trometamol and Tramadol Hydrochloride
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Placebo|DRUG: Dexketoprofen-single dose|DRUG: Tramadol-single dose|DRUG: Dexketoprofen/Tramadol-single dose|DRUG: Dexketoprofen-multiple doses|DRUG: Tramadol-multiple doses|DRUG: Dexketoprofen/Tramadol-multiple doses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Irreversible Electroporation(IRE) For Unresectable Prostatic Neoplasms
Status: WITHDRAWN
Conditions: Prostatic Neoplasms
Interventions: PROCEDURE: Irreversible electroporation (IRE)|DEVICE: NanoKnife
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Donor Mesenchymal Stem Cell Infusion in Treating Patients With Acute or Chronic Graft-Versus-Host Disease After Undergoing a Donor Stem Cell Transplant
Status: COMPLETED
Conditions: Cancer
Interventions: BIOLOGICAL: graft versus host disease prophylaxis/therapy|GENETIC: fluorescence in situ hybridization|OTHER: immunoenzyme technique|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|PROCEDURE: in vitro-treated bone marrow transplantation|PROCEDURE: management of therapy complications
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Culprit Lesion Only PCI Versus Multivessel PCI in Cardiogenic Shock
Status: COMPLETED
Conditions: Cardiogenic Shock|Acute Myocardial Infarction|Complications
Interventions: PROCEDURE: Immediate multivessel PCI|PROCEDURE: Culprit Lesion only PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Preoxygenation With Positive Airway Pressure: a Comparison of the Supine and 25° Head up Position
Status: COMPLETED
Conditions: Intubation;Difficult
Interventions: OTHER: 5 cmH2O CPAP|OTHER: head-up position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Impact of the Oncotype DX® Breast Cancer Assay on Treatment Decisions in a Canadian Population
Status: COMPLETED
Conditions: Hormone Receptor Positive Malignant Neoplasm of Breast
Interventions: OTHER: Questionnaires, Oncotype Dx Assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intra-tumoral Mitazalimab (CD40 Antibody) With Irreversible Electroporation (IRE) in Locally Advanced Pancreas Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: IRE + intratumoral mitazalimab (CD40 antibody) injection|DEVICE: NanoKnife
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Against Obstructive Sleep Apnea
Status: WITHDRAWN
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Ultrasound Exam|DEVICE: Polysomnography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety Study of GMDTC Injection in Participants With Excessive Cadmium
Status: RECRUITING
Conditions: Cadmium Exceeds the Standard
Interventions: DRUG: GMDTC for injection|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Interest of Tracheal Extubation in Positive Pressure on Postoperative Oxygenation in Adult Digestive Surgery: Prospective Randomized Study ExPress
Status: UNKNOWN
Conditions: Patients Undergoing Digestive Surgery With Orotracheal Intubation
Interventions: PROCEDURE: positive pressure extubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pelvic Floor Muscle Training(PFMT) on Lower Urinary Tract Symptoms (LUTS) in Men With Stroke
Status: COMPLETED
Conditions: Male|Stroke|Urinary Incontinence
Interventions: OTHER: Pelvic Floor Muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ledipasvir/Sofosbuvir Fixed-Dose Combination in Adults With Nosocomial Genotype 1 HCV Infection
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: LDV/SOF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strategies for Implementing a Postpartum Lifestyle Intervention in WIC Clinics
Status: RECRUITING
Conditions: Obesity|Gestational Diabetes|Lifestyle, Healthy|Glucose Intolerance During Pregnancy|PreDiabetes|Hyperglycemia
Interventions: BEHAVIORAL: In-person health coach delivery of the GLB|BEHAVIORAL: Technology-assisted health coach delivery of the GLB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study on Three Doses of an Inactivated COVID-19 Vaccine in Chinese Pulmonary Tuberculosis Patients
Status: UNKNOWN
Conditions: COVID-19|Pulmonary Tuberculosis
Interventions: BIOLOGICAL: Standard dosage inactivated vaccine|BIOLOGICAL: Double dosage inactivated vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Study on Echinocandins for Patients With Septic Shock Following Secondary Peritonitis
Status: COMPLETED
Conditions: Septic Shock|Peritonitis
Interventions: DRUG: Echinocandins
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Clevidipine Assessing Its Preoperative Antihypertensive Effect in Cardiac Surgery (ESCAPE-1)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: clevidipine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: HPV Serum Level and FDG PET CT in Patients With Cervical Cancer Treated With Radical Radiochemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Cancer
Interventions: DIAGNOSTIC_TEST: HPV serum level and FDG PET CT in patients with cervical cancer treated with radical radiochemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Acute Study of Effect of Ultrasound Vagus Nerve Stimulation on Glycemia
Status: SUSPENDED
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: Ultrasound Vagus Nerve Stimulation (DECIMA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Comparison of Bowel Cleansing Efficacy Between Same-day Dose Versus Split Dose
Status: COMPLETED
Conditions: Unrecognized Condition
Interventions: DRUG: Polyethylene Glycol (PEG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Compensatory Movements With Axon-Hook and Greifer in Transradial Amputees
Status: COMPLETED
Conditions: Transradial Amputation
Interventions: DEVICE: Greifer then Axon-Hook|DEVICE: Axon-Hook then Greifer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of DEH113 in the Treatment of Menstrual Cramp Pain in Primary Dysmenorrhea: a Pilot Study
Status: NOT_YET_RECRUITING
Conditions: Primary Dysmenorrhea
Interventions: DRUG: DEH113|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Conventional Dental Implants and Trabecular Metal™ Dental Implants After Sinus Floor Elevation
Status: COMPLETED
Conditions: Atrophy of Edentulous Alveolar Ridge|Partial Edentulism
Interventions: DEVICE: Two implant designs in a Sinus Bone Augmentation Procedure|DEVICE: Two implant designs in a Sinus Floor Elevation Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Rifaximin in Patients With Diabetic Gastroparesis
Status: RECRUITING
Conditions: Crohn Disease|Diabetic Gastroparesis
Interventions: DRUG: Rifaximin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Eltrombopag Plus Pulsed Dexamethasone for Subjects With Idiopathic Thrombocytopenic Purpura
Status: COMPLETED
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Versus Late Caffeine for ELBW Newborns
Status: TERMINATED
Conditions: Bronchopulmonary Dysplasia|Apnea of Prematurity
Interventions: DRUG: Caffeine|DRUG: Placebo (dextrose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Compare the Efficacy and Safety of SCENESSE and Narrow-Band Ultraviolet (NB-UVB) Light Versus NB-UVB Light Alone in Patients With Vitiligo
Status: RECRUITING
Conditions: Vitiligo
Interventions: DRUG: Afamelanotide and NB-UVB Light|PROCEDURE: NB-UVB Light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamic Orthotic Garment in Diplegic Cerebral Palsy
Status: UNKNOWN
Conditions: Diplegic Cerebral Palsy
Interventions: OTHER: Routine Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Venlafaxine for the Prevention of Depression in Patients With Head and Neck Cancer
Status: WITHDRAWN
Conditions: Head and Neck Cancer|Depression
Interventions: DRUG: Venlafaxine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Systemic Chemotherapy, Apatinib Plus Sintilimab for Metastasis ICC
Status: WITHDRAWN
Conditions: ICC
Interventions: DRUG: Systemic Chemotherapy|DRUG: Sintilimab|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2 Study of MRTX849 in Patients With Cancer Having a KRAS G12C Mutation KRYSTAL-1
Status: RECRUITING
Conditions: Advanced Cancer|Metastatic Cancer|Malignant Neoplastic Disease
Interventions: DRUG: MRTX849|DRUG: Pembrolizumab|DRUG: Cetuximab|DRUG: Afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing the Efficacy and Tolerability of Faslodex With Nolvadex in Postmenopausal Women With Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Metastasis
Interventions: DRUG: Fulvestrant|DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Ascending Multiple Dose Study of CD101 IV in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CD101 IV|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fibroblast Growth Factor-23 (FGF23) Reduction in Predialysis Chronic Kidney Disease (CKD)
Status: COMPLETED
Conditions: Kidney Disease
Interventions: DRUG: Lanthanum Carbonate|OTHER: 900 mg Phosphate Diet|DRUG: LC Placebo|OTHER: Ad Libitum Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Robotic Versus Thoracoscopy Versus Thoracotomy Repair for Congenital Esophageal Atresia
Status: ACTIVE_NOT_RECRUITING
Conditions: Congenital Esophageal Atresia
Interventions: PROCEDURE: Robotic repair for EA|PROCEDURE: Thoracoscopic repair for EA|PROCEDURE: Thoracotomy repair for EA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine, Docetaxel and Gemcitabine in Patients With Advanced Pancreas Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Capecitabine|DRUG: Docetaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FMT for MS Patients
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: Fecal Microbial Transplants|BIOLOGICAL: Fecal Microbial Transplants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Examine the Progression of Attention-Deficit Hyperactivity Disorder (ADHD) Drug Treatment and to Analyze Associated Factors
Status: COMPLETED
Conditions: Attention-deficit Hyperactivity Disorder
Interventions: DRUG: Methylphenidate hydrochloride|DRUG: Atomoxetine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Phase III Study of Icaritin Versus Sorafenib in PD-L1 Positive Advanced Hepatocellular Carcinoma Subjects
Status: TERMINATED
Conditions: Hepatocellular Carcinoma (HCC)
Interventions: DRUG: Icaritin|DRUG: Sorafenib Tosylate Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pegcrisantaspase in Combination With Venetoclax for Treatment of Relapsed or Refractory Acute Myeloid Leukemia (R/R AML)
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed or Refractory Acute Myeloid Leukemia
Interventions: DRUG: Venetoclax and pegcrisantaspase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Twice Daily Formoterol Versus Once Daily Tiotropium in Patients With GOLD A/B COPD
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Tiotropium|DRUG: Formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GOALS Cognitive Training Delivered to Aging Veterans in Person or Via Telehealth
Status: RECRUITING
Conditions: Brain Injuries, Traumatic|Executive Dysfunction
Interventions: OTHER: Home-based telehealth GOALS|OTHER: In-person GOALS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting CD19/CD20 Dual-targeted Cell in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Relapsed and Refractory B-cell Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: LUCAR-G39P cells product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within the United Kingdom
Status: COMPLETED
Conditions: Ocular Hypertension|Open Angle Glaucoma
Interventions: DRUG: timolol|DRUG: PhXA41
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Two Ab Interno Procedures in the Treatment of Glaucoma in Patients Undergoing Cataract Extraction
Status: COMPLETED
Conditions: Open Angle Glaucoma
Interventions: PROCEDURE: Goniotomy|DEVICE: Trabecular Micro-Bypass Stent|PROCEDURE: Cataract Extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CArdiovascular Risk Evaluation in Men With Prostate Cancer Study (CARE-PC) Pilot Feasibility Study
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: CARE-PC Web-Based Application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Identification of Cellular and Molecular Mechanisms Involved in the Pathophysiology of Alcohol Use Disorder by Examination of Cerebrospinal Fluid
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder
Interventions: OTHER: Spinal tap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Role of the Gut Microbiota in the Systemic Immune Response During Human Endotoxemia
Status: COMPLETED
Conditions: Endotoxemia
Interventions: DRUG: Endotoxin|DRUG: Vancomycin, Metronidazole, Ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Piperacllin Versus Placebo in Patients Undergoing Surgery for Acute Cholecystitis
Status: COMPLETED
Conditions: Cholecystitis, Acute
Interventions: DRUG: Piperacillin-tazobactam combination product|DRUG: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Weight Loss, Blood Sugar and Blood Lipid Effects of Tetrahydrocannabivarin (THCV) Impregnated Mucoadhesive Strips
Status: COMPLETED
Conditions: Metabolic Syndrome|Morbid Obesity|Hypercholesterolemia|Hyperglycemia
Interventions: DRUG: Tetrahydrocannabivarin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study to Assess the Efficacy and Safety of Luveris® (Lutropin Alfa) in Mid Follicular Phase for Controlled Ovarian Stimulation (COS) in Advanced Reproductive Age
Status: TERMINATED
Conditions: Infertility|Ovulation Induction
Interventions: DRUG: r-hLH + r-hFSH|DRUG: r-hFSH|DRUG: Recombinant Human Choriogonadotropin (r-hCG)|DRUG: GnRH antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Crocus Kozanis Administration in Obese Children and Adolescents
Status: COMPLETED
Conditions: PreDiabetes|Obesity|Dyslipidemias
Interventions: DIETARY_SUPPLEMENT: Crocus Kozanis|DIETARY_SUPPLEMENT: Placebo of Crocus Kozanis|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intra-Articular Injection of RegenoGel-OSP™ (Self-Plasma) and RegenoGel™ on Knee Pain in People Suffering From Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: RegenoGel-OSP, RegenoGel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of L-Tyrosine on 24 Hour Blood Pressure and Heart Rate in Parkinson's Disease
Status: COMPLETED
Conditions: Blood Pressure
Interventions: DIETARY_SUPPLEMENT: L-tyrosine|DIETARY_SUPPLEMENT: Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ofatumumab in Combination With Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine Sulfate, and Dexamethasone Alternating With Ofatumumab in Combination With Cytarabine and Methotrexate in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Stage I Mantle Cell Lymphoma|Stage II Contiguous Mantle Cell Lymphoma|Stage II Non-Contiguous Mantle Cell Lymphoma|Stage III Mantle Cell Lymphoma|Stage IV Mantle Cell Lymphoma
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Dexamethasone|DRUG: Doxorubicin Hydrochloride|OTHER: Laboratory Biomarker Analysis|DRUG: Methotrexate|BIOLOGICAL: Ofatumumab|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety, Tolerability, and Pharmacokinetics of PLN-74809 in Participants With Acute Respiratory Distress Syndrome (ARDS) Associated With at Least Severe COVID-19
Status: TERMINATED
Conditions: Acute Respiratory Distress Syndrome|SARS-CoV-2
Interventions: DRUG: PLN-74809|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Study of In-Stent Stenosis(I) After Flow Diverter(F) Based on 3D-DSA(D) Combined With TCCD(T)
Status: NOT_YET_RECRUITING
Conditions: Hemodynamics;In-stent Stenosis;Transcranial Doppler;Intracranial Aneurysm;Flow Diverter; Prospective Cohort Study
Interventions: OTHER: Flow Diverter Implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: pBFS Guided rTMS Therapy for Treatment-resistant Obsessive-Compulsive Disorder
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder|OCD
Interventions: DEVICE: active rTMS treatment|DEVICE: sham rTMS treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Videolaryngoscopic Intubation Using Macintosh vs.Hyperangulated Blades in Patients With Expected Difficult Intubation
Status: COMPLETED
Conditions: Intubation; Difficult or Failed|Videolaryngoscopy|General Anesthesia
Interventions: DEVICE: hyperangulated videolaryngoscope|DEVICE: Macintosh videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate Multiple Doses of GLPG2222 in Adult Subjects With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: GLPG2222 50 mg|DRUG: GLPG2222 100 mg|DRUG: Placebo|DRUG: GLPG2222 200 mg|DRUG: GLPG2222 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Effect of Captopril Versus Combination of Captopril and Pentoxifylline on Reducing Proteinuria in Type 2 Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: Captopril|DRUG: Captopril + Pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of A New Digestive Reconstruction Procedure Following Pancreatoduodenectomy
Status: UNKNOWN
Conditions: Pancreatic Cancer|Periampullary Carcinoma
Interventions: PROCEDURE: Modified method of digestive tract reconstruction|PROCEDURE: Routine digestive tract reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Multiple Oral Doses of JNJ-41443532 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: JNJ-41443532|DRUG: Pioglitazone 30 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Antimalarial Activity of Single Doses of OZ439 and PQP
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: 480 mg Piperaquine phosphate|DRUG: 640 mg Piperaquine phosphate|DRUG: 200 mg OZ 439|DRUG: 400 mg OZ 439|DRUG: 800 mg OZ 439|DRUG: 960 mg PQP|DRUG: 320 mg PQP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Transversus Abdominis Plane (TAP) Block for Post Caesarian Pain
Status: WITHDRAWN
Conditions: Obstetrical Complications From Sedation During Parturition
Interventions: DRUG: Bupivicaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S9628 Dexamethasone Plus Interferon Alfa in Treating Patients With Primary Systemic Amyloidosis
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: recombinant interferon alfa|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Proof of Concept Study of Maintenance Therapy With Tasquinimod in Patients With Metastatic Castrate-resistant Prostate Cancer Who Are Not Progressing After a First Line Docetaxel Based Chemotherapy
Status: TERMINATED
Conditions: Metastatic Castrate Resistant Prostate Cancer
Interventions: DRUG: Tasquinimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of Bilateral ESPB in Addition to Standard Analgesia at Reducing Opioid Consumption
Status: COMPLETED
Conditions: Anesthesia|Block
Interventions: PROCEDURE: Erecto Spinae nerve block|PROCEDURE: Multimodal Analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Andrographis Paniculata to GLP-1, Fasting Insulin, Insulin 2-h Post OGTT, and HOMA-IR
Status: COMPLETED
Conditions: Increased Insulin
Interventions: OTHER: Andrographis Paniculata Ext
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Direct Anterior Approach Versus Mini Posterior Approach Versous Lateral Approach for Displaced Femoral Neck Fractures
Status: UNKNOWN
Conditions: Hip Fractures|Femoral Neck Fractures
Interventions: PROCEDURE: Direct Anterior Approach Hemiarthroplasty|PROCEDURE: Mini Posterior Approach|PROCEDURE: Lateral approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validity and Reliability of Ultrasound Imaging for Measuring Coronal and Sagittal Angles in Idiopathic Scoliosis
Status: COMPLETED
Conditions: Ultrasonography|Coronal|Sagittal|Idiopathic Scoliosis|Validation Studies as Topic|Program Evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Study the Effects of Addition of Mebendazole to Lenvatinib in Cirrhotics With Advanced Hepatocellular Carcinoma.
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Liver Cirrhosis
Interventions: DRUG: Lenvatinib|DRUG: Mebendazole|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Indirect Calorimetry in Children Undergoing Non-invasive Ventilation
Status: COMPLETED
Conditions: Respiratory Insufficiency in Children|Noninvasive Ventilation|Nutrition Assessment
Interventions: DIAGNOSTIC_TEST: Indirect Calorimetry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Acupuncture and Herbal Treatment of Chronic HIV Sinusitis
Status: COMPLETED
Conditions: HIV Infections|Sinusitis
Interventions: DRUG: Clavulanate potassium|DRUG: Pseudoephedrine hydrochloride|DRUG: Amoxicillin trihydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Periacetabular Osteotomy With Versus Without Adjunctive Hip Arthroscopy
Status: UNKNOWN
Conditions: Hip Dysplasia
Interventions: PROCEDURE: Adjunctive hip arthroscopy to accompany PAO|PROCEDURE: PAO without adjunctive hip arthroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Benefit and Biomarker Analysis of Combination of PD-1/PD-L1 Immune Checkpoint Inhibitors and Radiotherapy
Status: RECRUITING
Conditions: HNSCC|NSCLC|Esophageal Cancer|Urothelial Carcinoma|Renal Cell Carcinoma|Squamous Cell Carcinoma of the Skin|Small Cell Bronchial Carcinomas
Interventions: OTHER: Conventional Therapy acc. to prevailing clincal approved schemes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase II Study of Optune (NovoTTF) in Combination With Bevacizumab (BEV) and Temozolomide (TMZ) in Patients With Newly Diagnosed Unresectable Glioblastoma (GBM)
Status: TERMINATED
Conditions: Cancer of Brain and Nervous System
Interventions: DEVICE: NovoTTF100A|DRUG: Bevacizumab|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Dose Escalation Study to Assess the Pharmacokinetics of of ASA404 in Adult Cancer Patients With Impaired Hepatic Function
Status: TERMINATED
Conditions: Histologically-proven and Radiologically-confirmed Solid Tumors
Interventions: DRUG: ASA404
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Correlational Study of PPV in Various VT in Mechanically Ventilated Patients
Status: COMPLETED
Conditions: Respiration, Artificial
Interventions: OTHER: 300 ml Hydroxyethyl Starch 130/0.4 and Sodium Chloride Injection infusing in 15 minutes if PPV under VT 8 ml/kg was larger than 13% in the initial investigation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Clinical Evaluation of a Daily Wear Silicone Hydrogel Lens
Status: COMPLETED
Conditions: Refractive Errors|Myopia|Hyperopia
Interventions: DEVICE: LID015385 contact lenses|DEVICE: Comfilcon A contact lenses|DEVICE: CLEAR CARE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Air-impingement Manipulation to Clear Subglottic Secretion Compared With Drainage Tube in Prolonged Intubated Patients
Status: UNKNOWN
Conditions: Ventilator Associated Pneumonia
Interventions: PROCEDURE: Manual air-impingement operation|DEVICE: subglottic secretion drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Carbon Nanoparticles and Indocyanine Green for Sentinel Lymph Node Biopsy in Early Stage Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer Stage IB1
Interventions: PROCEDURE: Carbon nanoparticles|PROCEDURE: Indocyanine green
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pomalidomide-Cyclophosphamide-Dexamethasone (PCD) Versus Pomalidomide-Dexamethasone (PD) in Relapse or Refractory Myeloma
Status: UNKNOWN
Conditions: Relapse Multiple Myeloma
Interventions: DRUG: PCD|DRUG: PD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genital Tract Infections, the Vaginal Microbiome and Gestational Age at Birth Among Pregnant Women in South Africa
Status: ACTIVE_NOT_RECRUITING
Conditions: Sexually Transmitted Infections (Not HIV or Hepatitis)|Premature Birth|Pregnancy; Infection|Microbial Colonization|Chlamydia Trachomatis Infection|Neisseria Gonorrheae Infection|Trichomonas Vaginitis|Mycoplasma Genitalium Infection|Bacterial Vaginosis|Vaginal Candida|Ureaplasma Urealyticum Infection|Genital Mycoplasma Infection|HIV Infections
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Novel Formulation of Pasteurized Maple Cough Syrup Compared With Placebo on Nocturnal Cough and Sleep Quality in Infants With Upper Respiratory Infection
Status: TERMINATED
Conditions: Cough|Upper Respiratory Infection|Nocturnal Cough
Interventions: DIETARY_SUPPLEMENT: Pasteurized maple syrup|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: L-Tyrosine Supplementation in Patients With Fibromyalgia
Status: TERMINATED
Conditions: Fibromyalgia
Interventions: DRUG: Tyrosine|DRUG: Tyrosine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Concomitant Administration of RT With Cisplatin in Standard Infusion or Fractional Infusion
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Split Cisplatin|DRUG: Cisplatin|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ARRY-520 in Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma|Plasma Cell Leukemia
Interventions: DRUG: ARRY-520, KSP(Eg5) inhibitor; intravenous|DRUG: Filgrastim, granulocyte-colony stimulating factor (G-CSF); subcutaneous|DRUG: Dexamethasone, steroid; oral
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is High Intensity Interval Training Effective to Reduce the Waist Circumference and Fat Percentage at Trunk Region
Status: COMPLETED
Conditions: Overweight|Physically Inactive|Adults
Interventions: OTHER: High Intensity Interval Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Chiropractic Cervical Manipulation in Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: OTHER: Chiropractic Cervical Manipulation|OTHER: Sham Technique Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Osteoporosis and Fall Prevention High Risk Population Intervention and Follow up in the Metropolitan Area
Status: COMPLETED
Conditions: Osteoporosis|Fracture
Interventions: BEHAVIORAL: Integrated care (IC)|BEHAVIORAL: Lower extremity exercise (LEE)|BEHAVIORAL: Home care (HC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Surgical Therapy for BPH
Status: TERMINATED
Conditions: Benign Prostatic Hyperplasia
Interventions: DEVICE: Transurethral Microwave Thermotherapy (TUMT)|DEVICE: Transurethral Needle Ablation (TUNA) Therapy|DRUG: Finasteride and Alfuzosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Combination Chemotherapy in Patients With Metastatic Solid Tumors or Adenocarcinoma of the Pancreas
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: DRUG: gemcitabine; irinotecan; leucovorin; 5-fluorouracil; oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Desensitising Effect of Nanosilver Fluoride in Molar-Incisor Hypomineralisation
Status: ACTIVE_NOT_RECRUITING
Conditions: Molar Incisor Hypomineralization|Hypersensitivity
Interventions: DEVICE: Low-level laser therapy|DRUG: Nanosilver fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Toolkit for School Behavior Modification in Children With Attention-Deficit/Hyperactivity Disorder (ADHD)
Status: UNKNOWN
Conditions: Attention-deficit/Hyperactivity Disorder
Interventions: BEHAVIORAL: ADHD Toolkit|OTHER: Waiting List Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Re-irradiation With NBTXR3 in Combination With Pembrolizumab for the Treatment of Inoperable Locoregional Recurrent Head and Neck Squamous Cell Cancer
Status: WITHDRAWN
Conditions: Recurrent Head and Neck Squamous Cell Carcinoma|Unresectable Head and Neck Squamous Cell Carcinoma
Interventions: OTHER: Hafnium Oxide-containing Nanoparticles NBTXR3|PROCEDURE: Intensity-Modulated Proton Therapy|RADIATION: Intensity-Modulated Radiation Therapy|BIOLOGICAL: Pembrolizumab|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Curcumin in Management of Chronic Obstructive Pulmonary Disease
Status: UNKNOWN
Conditions: COPD
Interventions: DIETARY_SUPPLEMENT: Curcumin therapy|OTHER: Placebo|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Effects of a Single Dose of Prednisone on Biomarkers of Allergen Responses in Asthmatics (MK-0000-175)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Prednisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison in Marginal Adaptation Between Conventional and Gull Wing Preparation in Laminates Veneers
Status: UNKNOWN
Conditions: Teeth Sensitivity
Interventions: PROCEDURE: gull wing preparation of laminates veneers|PROCEDURE: conventional preparation of laminates veneers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Mechanisms of Pharmacologic Treatment of Fecal Incontinence
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: DRUG: Psyllium powder|DRUG: Loperamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Efficacy and Safety of MXP22 on Liver Health
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: OTHER: MXP22 (Probiotic and antioxidant capsule)|OTHER: Placebo (Microcrystalline Cellulose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Monitoring of Fluid Status in Heart Failure Patients by Intrathoracic Impedance Measurement in Japan (J-HomeCARE II)
Status: COMPLETED
Conditions: Heart Failure|Arrhythmias, Cardiac
Interventions: DEVICE: ICD/CRT-D
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Root Coverage After the Use of Coronally Advanced Flap Either With Advanced Paltelet Rich Fibrin or Subepithilial Connective Tissue Graft in Treatment of Miller Class I and II Gingival Recession.
Status: UNKNOWN
Conditions: Gingival Recession
Interventions: PROCEDURE: CAF + (A-PRF)|PROCEDURE: CAF+SCTG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of The Abuse Liability Potential of RO4917838 in Recreational Drug Users
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Placebo|DRUG: RO4917838|DRUG: diazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: An Open-label, Phase 1/2 Trial of Gene Therapy 4D-310 in Adults With Fabry Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Fabry Disease
Interventions: BIOLOGICAL: 4D-310
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin to Prevent Metabolic Complications in Glucocorticoid Excess
Status: COMPLETED
Conditions: Patients With Glucocorticoid Treatment
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mobile App-treatment of Mixed and Urgency Urinary Incontinence in Women
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DEVICE: Tät®II Information app|DEVICE: Tät®II Treatment app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Opioid Dependent Patients With Suboxone: Acceptability & Safety Data From Real Life Scenario (Study P05603)
Status: COMPLETED
Conditions: Opioid-Related Disorders|Opiate Dependence|Drug Abuse
Interventions: DRUG: Buprenorphine/Naloxone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase III Study of ICI35,868 (Diprivan) With and Without EES0000645/A (SDS) on Gastrointestinal Endoscopy
Status: COMPLETED
Conditions: Sedation to be Moderate for a Diagnostic Gastrointestinal Endoscopy and Gastrointestinal Endoscopic Polypectomy
Interventions: DRUG: Intralipid|DRUG: ICI35,868 (Diprivan)|DRUG: ICI35,868 (Diprivan) + EES0000645/A (SDS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of β-hydroxy-β-methylbutyrate Supplementation on Physical Capacity and Body Composition in Trained Athletes
Status: COMPLETED
Conditions: Sport|Supplements|Supplementation
Interventions: DIETARY_SUPPLEMENT: β-hydroxy-β-methylbutyrate and a placebo supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microbiota Diversity and Composition and Polyphenol Bioavailability
Status: COMPLETED
Conditions: Fecal Microbiota
Interventions: OTHER: cranberry|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Using mHealth Tools to Deliver Integrated Community Case Management (ICCM) to Village Health Team (VHT) Volunteers.
Status: UNKNOWN
Conditions: Community Health Services|Telemedicine
Interventions: DEVICE: Amazon Fire Tablet|OTHER: ICCM Traditional Trainins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: DCb (Docetaxel/Carboplatin) Versus EC-D (Epirubicin/Cyclophosphamide Followed by Docetaxe) as Neoadjuvant Chemotherapy for Triple-Negative Breast Cancer
Status: COMPLETED
Conditions: Triple-Negative Breast Cancer
Interventions: DRUG: DCb (docetaxel/carboplatin) versus EC followed by D (epirubicin/cyclophosphamide followed by docetaxe)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heliox for Neonate With Acute Respiratory Distress Syndrome (ARDS)
Status: UNKNOWN
Conditions: ARDS
Interventions: DRUG: heliox combined with MV|DRUG: MV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spironolactone on Fibrosis Progrssion-Portal Hypertension(FP-PH)in Cirrhosis
Status: COMPLETED
Conditions: Cirrhosis|Portal Hypertension
Interventions: DRUG: Spironolactone and carvedilol|DRUG: Carvedilol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate H56:IC31 in Preventing Rate of TB Recurrence
Status: ACTIVE_NOT_RECRUITING
Conditions: Tuberculosis, Pulmonary
Interventions: BIOLOGICAL: H56:IC31|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION