pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pain Control Following Total Hip Arthroplasty
Status: COMPLETED
Conditions: Chronic Postoperative Pain
Interventions: DRUG: Bupivacaine Hydrochloride 0.25% Injection Solution_#2|DRUG: EPINEPHrine 1:200,000 / Prilocaine HCl 4 % 1.8 ML Cartridge|DRUG: Bupivacaine Hydrochloride 0.5% Injection Solution_#2|DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Enhanced Recovery After Surgery in Patients Undergoing Laparoscopic Colorectal Cancer Resection
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DEVICE: acupuncture|OTHER: early recovery program after surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Response of Brain Metastases After Gamma-Knife Radiosurgery Using Dynamic Susceptibility-weighted Contrast-enhanced Perfusion Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Brain Metastases
Interventions: DEVICE: dynamic susceptibility-weighted contrast-enhanced perfusion magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Therapy With High-flow Oxygen by Nasal Cannula vs Noninvasive Ventilation in Patients With Acute Hypoxemic Respiratory Failure: a Crossover Physiologic Study
Status: UNKNOWN
Conditions: Hypoxemia
Interventions: DEVICE: Optiflow (High-flow Nasal Cannula)|DEVICE: Non-invasive Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bone Healing in Healthy and Post-menopausal Osteoporotic Women
Status: WITHDRAWN
Conditions: Post-menopausal Osteoporosis
Interventions: PROCEDURE: tooth extraction|RADIATION: CBCT scan|RADIATION: DXA scan|RADIATION: Panoramic radiograph
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Evaluate Pregabalin and Acetaminophen in Healthy Volunteers
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Pregabalin 100mg|DRUG: Acetaminophen 1300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Envarsus XR® on Kidney Biopsy Subclinical Rejection and Blood Immunologic Profile
Status: RECRUITING
Conditions: End Stage Renal Disease
Interventions: DRUG: Tacrolimus|DRUG: Envarsus XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postprandial Lipid Metabolism in Familial Hypercholesterolaemia:Effects of Fish Oils
Status: UNKNOWN
Conditions: Hypertriglyceridaemia|Familial Hypercholesterolaemia
Interventions: DIETARY_SUPPLEMENT: Fish oil capsule|DRUG: HMG Coenzyme reductase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney Tumors
Status: COMPLETED
Conditions: Childhood Renal Cell Carcinoma|Clear Cell Renal Cell Carcinoma|Clear Cell Sarcoma of the Kidney|Papillary Renal Cell Carcinoma|Rhabdoid Tumor of the Kidney|Stage I Renal Cell Cancer|Stage I Renal Wilms Tumor|Stage II Renal Cell Cancer|Stage II Renal Wilms Tumor|Stage III Renal Cell Cancer|Stage III Renal Wilms Tumor|Stage IV Renal Cell Cancer|Stage IV Renal Wilms Tumor
Interventions: DRUG: Doxorubicin Hydrochloride|DRUG: Irinotecan Hydrochloride|PROCEDURE: Conventional Surgery|DRUG: Cyclophosphamide|DRUG: Etoposide|DRUG: Carboplatin|BIOLOGICAL: Dactinomycin|DRUG: Vincristine Sulfate|RADIATION: Radiation Therapy|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Verdiperstat on Microglial Activation in Well-characterized MSA Patients
Status: COMPLETED
Conditions: Multiple System Atrophy|Multiple System Atrophy, Cerebellar Variant|Multiple System Atrophy, Parkinson Variant (Disorder)|Multiple System Atrophy (MSA) With Orthostatic Hypotension
Interventions: DRUG: [F-18]PBR06|DRUG: Verdiperstat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Additional Functional Strength Training on Mobility in Children With Hemiplegic Cerebral Palsy
Status: COMPLETED
Conditions: Hemiplegic Cerebral Palsy|Mobility
Interventions: OTHER: Functional Strength Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bendamustine, Cytarabine, Etoposide and Melphalan (BeEAM) as Conditioning for Autologous Stem Cell Transplant (ASCT) in Aggressive Non Hodgkin's Lymphoma (NHL).
Status: COMPLETED
Conditions: Bendamustine|Conditioning Therapy|Autologous Stem Cell Transplant|Aggressive Non Hodgkin's Lymphoma
Interventions: DRUG: Bendamustine-EAM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doubleblinded RCT of the Omnilux on Lower Extremity Surgical Wounds Left to Heal by Second Intention
Status: TERMINATED
Conditions: Wound
Interventions: DEVICE: Omnilux|DEVICE: Omnilux Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiolabeled Glass Beads in Treating Patients With Liver Cancer That Cannot be Removed by Surgery
Status: COMPLETED
Conditions: Adult Primary Hepatocellular Carcinoma|Advanced Adult Primary Liver Cancer|Localized Unresectable Adult Primary Liver Cancer|Recurrent Adult Primary Liver Cancer
Interventions: RADIATION: yttrium Y 90 glass microspheres|OTHER: laboratory biomarker analysis|DRUG: TheraSphere
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bandage Lenses in Treating Patients With Ocular Graft-Versus-Host Disease
Status: COMPLETED
Conditions: Graft Versus Host Disease|Ophthalmologic Complications
Interventions: BIOLOGICAL: graft versus host disease prophylaxis/therapy|OTHER: questionnaire administration|PROCEDURE: optical coherence tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cetuximab in Patients With Lung Adenocarcinoma Receiving Erlotinib That Have Developed "Acquired Resistance" to Erlotinib
Status: COMPLETED
Conditions: Lung Adenocarcinoma
Interventions: DRUG: erlotinib with cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Oral Versus Subcutaneous Route of Methotrexate Administration in Moderate to Severe Psoriasis
Status: UNKNOWN
Conditions: Psoriasis Vulgaris
Interventions: DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Olmesartan Medoxomil on Coronary Atherosclerosis and Epicardial Adipose Tissue(EAT)
Status: UNKNOWN
Conditions: Coronary Atherosclerosis
Interventions: DRUG: Olmesartan medoxomil tablets|DRUG: Antihypertensive medication (per doctor suggestion)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple-portal VATS Versus Uniportal VATS Lobectomy for Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: PROCEDURE: Uniportal VATS|PROCEDURE: Conventional VATS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Legflow Versus Bare Balloon Angioplasty for Treatment of Atherosclerotic Disease
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DEVICE: Legflow® balloon|DEVICE: Standard PTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-term Safety Study of Olumacostat Glasaretil Gel in Subjects With Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Olumacostat Glasaretil Gel, 5.0%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnosis of Patients With Low or Intermediate Suspicion of SAHS or With Comorbidity: Standard Laboratory Polysomnography Compared With Three Nights of Home Respiratory Polygraphy.
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DEVICE: Home Respiratory Polygraphy|DEVICE: Standard Polysomnography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Study Between Bilateral and Unilateral Spinal Anaesthesia
Status: TERMINATED
Conditions: Anesthesia; Adverse Effect, Spinal and Epidural
Interventions: PROCEDURE: bilateral spinal anesthesia|PROCEDURE: unilateral spinal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scandinavian Starch for Severe Sepsis/Septic Shock Trial
Status: COMPLETED
Conditions: Severe Sepsis|Septic Shock
Interventions: DRUG: 6% Hydroxyethyl starch 130/0.4|DRUG: Ringers acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Effect of an Amino Acid Mixture on Lean Body Mass (LBM) in Post-bariatric Surgery Patients
Status: COMPLETED
Conditions: Obesity|Post-gastric Bypass
Interventions: DIETARY_SUPPLEMENT: receive amino acid supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Retrospective Study to Assess the Impact of the Use of Interferon in Patients With Chronic Hepatitis C (DECISION)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Conventional Interferon|DRUG: Peginterferon Alfa-2a|DRUG: Peginterferon Alfa-2b|DRUG: Ribavirin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess the Blood Levels and Safety of Olaparib in Patients With Advanced Solid Tumours and Normal or Impaired Kidney Function
Status: COMPLETED
Conditions: Solid Tumours
Interventions: DRUG: Olaparib tablet dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Postoperative Additive Systemic Steroids in CRSwNP
Status: COMPLETED
Conditions: Sinusitis, Chronic
Interventions: DRUG: Systemic Steroid (Prednisolone)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Investigation of a Sub-Conjunctival Insert
Status: TERMINATED
Conditions: Diabetes Care
Interventions: DEVICE: GOMIS and Photometer|DEVICE: GOMIS and Photometer|DEVICE: GOMIS and Photometer|DEVICE: GOMIS and Photometer|DEVICE: GOMIS and Photometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of TTNS in MS Patients With Lower Urinary Track Symptoms
Status: RECRUITING
Conditions: Multiple Sclerosis|Lower Urinary Tract Symptoms
Interventions: BEHAVIORAL: Pelvic floor exercises|DEVICE: Transcutaneous posterior tibial nerve stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Efficacy of POLYGYNAX® in the Empirical Treatment of Infectious Vaginitis
Status: COMPLETED
Conditions: Vaginitis
Interventions: DRUG: POLYGYNAX®|DRUG: GYNODAKTARIN®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Aflibercept in Combination With FOLFIRI Chemotherapy as 1st Line Treatment for Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: FOLFIRI Protocol|DRUG: Aflibercept Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conditioning Treatment With Umbilical Cord Blood Transplant for Hematologic Malignancies
Status: TERMINATED
Conditions: Hematologic Malignancies
Interventions: DRUG: Fludarabine|DRUG: Busulfan|DRUG: Thymoglobulin|RADIATION: Total Body Irradiation|BIOLOGICAL: Umbilical Cord Blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of OMT on ANS: a Thermography Study
Status: COMPLETED
Conditions: Autonomic Nervous System Imbalance|Healthy
Interventions: OTHER: osteopathic treatment|OTHER: sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acute Effects of SATIOSTAT Ingestion on Satiation Hormones, Gastric Emptying, Subjective Feelings of Appetite and Energy Intake
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Control treatment + oral glucose|DIETARY_SUPPLEMENT: SATIOSTAT treatment + oral glucose|DIETARY_SUPPLEMENT: Control treatment + meal intake|DIETARY_SUPPLEMENT: SATIOSTAT treatment + meal intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Evaluating the Effects of Lebrikizumab on Airway Eosinophilic Inflammation in Participants With Uncontrolled Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Lebrikizumab|DRUG: Placebo|DRUG: Inhaled corticposteroids (ICS)|DRUG: Second Asthma Controller Medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Cancer Vaccine (Labvax 3(22)-23) and GM-CSF Alone or in Combination With Pembrolizumab for the Treatment of Advanced Stage Adenocarcinoma
Status: RECRUITING
Conditions: Advanced Adenocarcinoma|Advanced Malignant Solid Neoplasm|Metastatic Adenocarcinoma|Metastatic Malignant Solid Neoplasm|Recurrent Adenocarcinoma|Recurrent Malignant Solid Neoplasm
Interventions: BIOLOGICAL: Antineoplastic Vaccine|BIOLOGICAL: Sargramostim|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of NKTR-102 in Patients With Metastatic or Locally Advanced Ovarian Cancer
Status: COMPLETED
Conditions: Tumor|Ovarian Cancer
Interventions: DRUG: NKTR-102 q14d|DRUG: NKTR-102 q21d
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study of a New Medicine NNC0113-6856 in Healthy Males
Status: COMPLETED
Conditions: Healthy Volunteers|Type 2 Diabetes
Interventions: DRUG: NNC0113-6856|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultraviolet and UV-Visible Light Photoprotection for the Treatment of Melasma
Status: COMPLETED
Conditions: Melasma
Interventions: DRUG: 290-400 nm sunscreen|DRUG: 290-800 nm sunscreen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Checking Intervention for Maladaptive Beliefs About Memory
Status: TERMINATED
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: CBT for Maladaptive Beliefs about Memory|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Isometric Preoperative Exercise on Autologous Arteriovenous Fistulas. Randomized Clinical Trial
Status: COMPLETED
Conditions: Arteriovenous Fistula Thrombosis|Arteriovenous Fistula Stenosis
Interventions: DEVICE: Isometric exercises using Hand grip and elastic bands
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Monitoring Neoadjuvant Chemotherapy Response in Breast Cancer Patients Using Diffuse Optical Spectroscopic Imaging
Status: ENROLLING_BY_INVITATION
Conditions: Breast Cancer
Interventions: DEVICE: Diffuse Optical Spectroscopy Imaging (DOSI) - Neoadjuvant Chemo (NAC) Cohort|DEVICE: Diffuse Optical Spectroscopy Imaging (DOSI) - Non-NAC Cohort
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Transdiagnostic Treatment of Emotional Disorders for Women in a Homeless Situation
Status: TERMINATED
Conditions: Anxiety|Depression
Interventions: BEHAVIORAL: Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP)|BEHAVIORAL: Same than experimental condition (UP), after it finishes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cryoablation Combined With Tislelizumab Plus Lenvatinib In Previously Treated Gastric Cancer Liver Metastasis (CASTLE-09)
Status: RECRUITING
Conditions: Gastric Cancer Metastatic to Liver
Interventions: PROCEDURE: Cryoablation|DRUG: Tislelizumab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Lingzhi on Disease Progression in Patients With Untreated Early Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DRUG: Ganoderma|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Resection of Gastrointestinal Neoplasms
Status: UNKNOWN
Conditions: Endoscopic Mucosal Resection|Endoscopic Submucosal Dissection|Gastric Neoplasm|Colonic Neoplasms|Esophageal Neoplasms|Duodenal Neoplasms
Interventions: PROCEDURE: Endoscopic resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial Evaluating the Efficacy and Safety of ZL-2306 (Niraparib) in Ovarian Cancer Patient
Status: ACTIVE_NOT_RECRUITING
Conditions: Platinum-sensitive Relapsed Ovarian Cancer
Interventions: DRUG: ZL-2306(nirapairb)|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Immunogenicity and Safty Study of Recombinant Human Papillomavirus Vaccine(6,11,16,18,31,33,45,52,58 Type)(E.Coli)
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Intraepithelial Neoplasia|Cervical Cancer|Condylomata Acuminata
Interventions: BIOLOGICAL: Nonavalent HPV vaccine|BIOLOGICAL: Bivalent HPV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Efficacy and Safety of Orelabrutinib in Adult Patients With Chronic Primary Immune Thrombocytopenia
Status: RECRUITING
Conditions: Chronic Primary Immune Thrombocytopenia (ITP)
Interventions: DRUG: Orelabrutinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Autologous Anti-CD22 Chimeric Antigen Receptor Redirected T Cells In Patients With Chemotherapy Resistant Or Refractory Acute Lymphoblastic Leukemia
Status: TERMINATED
Conditions: Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: CART22 cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Hydromorphone Hydrochloride (HCl) Oral Osmotic System (OROS) in the Reduction of Breakthrough Pain Medication Frequency in Participants With Cancer
Status: COMPLETED
Conditions: Cancer|Pain
Interventions: DRUG: Hydromorphone HCl OROS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ChangeGradients: Promoting Adolescent Health Behavior Change
Status: NOT_YET_RECRUITING
Conditions: Alcohol Drinking|Self Efficacy|Adolescent Behavior|Risk-Taking|Cancer
Interventions: BEHAVIORAL: ChangeGradients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Bisoprolol (Nerkardou - Nerhadou International) 5 and 10 mg Oral Dissolvable Film (ODF) Treatment in Egyptian Patients With Essential Hypertension
Status: RECRUITING
Conditions: Essential Hypertension
Interventions: DRUG: Nerkardou (5 mg) & (10 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obatoclax Mesylate in Samples From Young Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: gene expression analysis|GENETIC: microarray analysis|GENETIC: protein expression analysis|GENETIC: reverse transcriptase-polymerase chain reaction|GENETIC: western blotting|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tremelimumab and Durvalumab in Treating Patients With Colorectal Cancer With Liver Metastases That Can Be Removed by Surgery
Status: COMPLETED
Conditions: Metastatic Carcinoma in the Liver|Resectable Mass|Stage IV Colorectal Cancer AJCC v7|Stage IVA Colorectal Cancer AJCC v7|Stage IVB Colorectal Cancer AJCC v7
Interventions: BIOLOGICAL: Durvalumab|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Therapeutic Conventional Surgery|BIOLOGICAL: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Non-invasive Brain Stimulation on Language Production in Post-stroke Aphasia
Status: COMPLETED
Conditions: Aphasia|Stroke|Language Disorders
Interventions: BEHAVIORAL: Language treatment for improving discourse production|DEVICE: Transcranial direct-current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Video Game Hearing Tests for Remote Monitoring of Ototoxicity
Status: RECRUITING
Conditions: Aminoglycoside Toxicity|Aminoglycoside-Induced Hearing Loss|Hearing Loss|Video Games
Interventions: OTHER: video game hearing tests|OTHER: Audio-training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of HFCWO Vests on Spirometry Measurements
Status: COMPLETED
Conditions: Cystic Fibrosis|Bronchiectasis
Interventions: DEVICE: International Biophysics AffloVest|DEVICE: Hill-Rom Monarch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess YH001 in Combination With Toripalimab Injection in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumor
Interventions: DRUG: YH001|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of the Absence of Nasogastric Decompression After Pancreaticoduodenectomy
Status: COMPLETED
Conditions: Digestive System Surgical Procedure|Pancreaticoduodenectomy
Interventions: DEVICE: no nasogastric tube|DEVICE: nasogastric tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Novel Intervention to Promote Engagement in Physical Activity for Individuals With Whiplash Associated Disorder
Status: COMPLETED
Conditions: Whiplash Injuries|Sedentary Lifestyle
Interventions: BEHAVIORAL: intervention|OTHER: B|OTHER: Follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Evaluating Efficacy and Safety of Anticoagulation in Patients With COVID-19 Infection, Nested in the Corimmuno-19 Cohort
Status: UNKNOWN
Conditions: COVID19 Pneumonia
Interventions: DRUG: Tinzaparin or unfractionated heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance of Injectable Composite Versus Dual Cured Cement in Cementation of Indirect Restoration: A Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Cementation Teeth|Badly Broken Down Vital Teeth
Interventions: OTHER: injectable composite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hybrid Effectiveness-Implementation Trial of a School Clinician Training and Psychosocial ADHD/ODD Intervention Program Adapted for Schools Across Mexico
Status: NOT_YET_RECRUITING
Conditions: ADHD
Interventions: BEHAVIORAL: CLS-A-FUERTE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: L-carnitine for Fatigue in COPD
Status: COMPLETED
Conditions: Copd|Fatigue
Interventions: DIETARY_SUPPLEMENT: L-carnitine 1000 mg twice daily|BEHAVIORAL: Weekly health coaching calls|DIETARY_SUPPLEMENT: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clomiphene Citrate Versus Tamoxifen for Ovulation Induction in PCOs
Status: COMPLETED
Conditions: PCOS
Interventions: DRUG: Clomiphene citrate|DRUG: Tamoxifen Placebo|DRUG: Tamoxifen|DRUG: Clomiphene citrate placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving Outcomes for Low-Income Mothers With Depression
Status: COMPLETED
Conditions: Post Partum Depression
Interventions: BEHAVIORAL: Engagement-Focused Care Coordination|BEHAVIORAL: Problem Solving Education (PSE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Glutamine and Vitamin C on Interleukin-6 and Clinical Outcomes in Surgical Intensive Care Unit Patients
Status: COMPLETED
Conditions: Critical Care
Interventions: DIETARY_SUPPLEMENT: Glutamine and vitamin C enteral supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of Nesiritide (BNP) in Kidney Function in Patients With Congestive Heart Failure (CHF) and Kidney Failure
Status: TERMINATED
Conditions: Cardiorenal Syndrome
Interventions: DRUG: Nesiritide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Tolerability of Rozanolixizumab in Adult Study Participants With Persistent or Chronic Primary Immune Thrombocytopenia (ITP)
Status: TERMINATED
Conditions: Primary Immune Thrombocytopenia
Interventions: DRUG: Rozanolixizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Extended Infusion Set Wear Using Medtronic Extended Wear Sof-set Infusion Set
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Extended Wear infusion set|DEVICE: Standard Infusion set|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 7-hydroxystaurosporine and Topotecan Hydrochloride in Treating Patients With Relapsed or Progressed Small Cell Lung Cancer
Status: COMPLETED
Conditions: Extensive Stage Small Cell Lung Cancer|Recurrent Small Cell Lung Cancer
Interventions: DRUG: topotecan hydrochloride|DRUG: 7-hydroxystaurosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Real World Study to Capture Clinical and Patient Centered Outcomes in Adults With Severe Eosinophilic Asthma Treated With Benralizumab.
Status: ACTIVE_NOT_RECRUITING
Conditions: Severe Eosinophilic Asthma
Interventions: DRUG: Cohort
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Depression Levels in Elderly Patients With an Orthopedic Fracture Compared to Patients After a Stroke.
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression|Old Age; Debility|Stroke|Fractures, Bone
Interventions: DIAGNOSTIC_TEST: Geriatric Depression Scale - 15
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Comparing Dural Puncture Epidural With Epidural and Combined Spinal Epidural Anesthesia for Obstetric Analgesia.
Status: UNKNOWN
Conditions: Obstetric Pain|Analgesia
Interventions: PROCEDURE: Dural puncture|PROCEDURE: Combined spinal epidural analgesia|PROCEDURE: Epidural analgesia|DRUG: Sufentanyl/Levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuum of Care in Hospitalized Patients With Opioid Use Disorder and Infectious Complications From Drug Use
Status: NOT_YET_RECRUITING
Conditions: Opioid Use Disorder|Injection Related Infections
Interventions: BEHAVIORAL: Integrated Infectious Diseases and Medication for Opioid Use Disorder Clinic (IC)|BEHAVIORAL: NavSTAR-CHOICE (NS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy of a Polyamine-deficient Diet for Treating Postoperative Pain After Abdominal Surgery
Status: RECRUITING
Conditions: Digestive System Surgical Procedures
Interventions: OTHER: Polyamine Deficient Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Lung Transplant READY Pilot Study
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: BEHAVIORAL: Investigator-designed lung transplant education resource (Research Intervention)|BEHAVIORAL: Publicly available transplant education resource (Attention Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: HYPOCHLOROUS ACID SUBSTANTIVITY AS ANTIPLAQUE AGENT (HOCl-SAP)
Status: COMPLETED
Conditions: Hypochlorous Acid|Mouthwashes
Interventions: DRUG: Hypochlorous Acid|DRUG: Chlorhexidine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sublingual Buprenorphine Through Telemedicine vs In-Person Care as Usual
Status: NOT_YET_RECRUITING
Conditions: Opioid Use Disorder
Interventions: DRUG: Buprenorphine SL|OTHER: Telehealth|OTHER: In-person treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The New Position of Radial Artery Puncture and Cannulation of the Patient With Surgery（RAPC-02）
Status: NOT_YET_RECRUITING
Conditions: The New Position of Radial Artery Puncture and Cannulation of the Patient With Surgery
Interventions: PROCEDURE: The puncture site is within 2-4 cm above the second wrist transverse crease|PROCEDURE: The puncture site is within 0-1.9 cm above the second wrist transverse crease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of AZD5363 in Combination With Paclitaxel, in Advanced Gastric Adenocarcinoma Patients Harboring PIK3CA Mutation and/or PIK3CA Amplification as a Second-line Chemotherapy
Status: COMPLETED
Conditions: Advanced Gastric Cancer
Interventions: DRUG: AZD5363|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Home Delivered Meal Program on Obese Elderly African American Subjects With Type 2 Diabetes Mellitus (DM)
Status: TERMINATED
Conditions: Obesity|Diabetes
Interventions: DIETARY_SUPPLEMENT: home-delivered meals|DIETARY_SUPPLEMENT: home-delivered meals|BEHAVIORAL: diabetes education for 12 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison Between Clear Aligners and Traditional Fixed Appliances in the Treatment of Four-premolar-extraction Cases
Status: COMPLETED
Conditions: Malocclusion, Angle Class I|Malocclusion; Displaced or Missing Teeth|Crowding
Interventions: DEVICE: Fixed Appliances|DEVICE: Clear Aligners
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra and Postoperative Outcomes With 3 Injectors
Status: COMPLETED
Conditions: Cataract
Interventions: PROCEDURE: Intraocular lens implantation|DEVICE: Autosert Injector|DEVICE: Royale Injector|DEVICE: Monarch III Injector
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Assessment of the Efficacy and Effects of Different Skincare Regimens on Infants
Status: COMPLETED
Conditions: Baby Skin Development
Interventions: OTHER: Johnson's Baby Top-To-Toe Wash|OTHER: Johnson's Baby Lotion|OTHER: Water (in lieu of bathing products)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II Clinical Trial of Percutaneous Ventricular Restoration Using Heartech® Device Preventing Heart Failure Post Myocardial Infarction (The Partical Study)
Status: UNKNOWN
Conditions: Efficacy, Safty, Device
Interventions: DEVICE: percutaneous ventricular restoration using heartech® device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Timolol Option for Ulcerated Hemangiomas (TOUCH Trial)
Status: WITHDRAWN
Conditions: Infantile Hemangiomas
Interventions: DRUG: Timolol 0.5% Gel Forming Solution (GFS)|DRUG: Mupirocin 2% Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Metoprolol in the Prevention of Vasovagal Syncope in Aging Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Vasovagal Syncope
Interventions: DRUG: Metoprolol|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bystander Fatigue and CPR Quality Using Continuous Compressions Versus 30:2 Compressions to Ventilation
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: PROCEDURE: CPR using 30:2 ratio|PROCEDURE: CPR using continuous compressions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study Evaluating the Efficacy and Safety of HSK3486
Status: COMPLETED
Conditions: Sedation and Anesthesia for Adult Colonoscopy Procedures
Interventions: DRUG: HSK3486|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EOIFP Block Versus OSTAP Block for Upper Abdominal Surgery
Status: RECRUITING
Conditions: Open Abdominal Surgery
Interventions: PROCEDURE: Oblique Subcostal Transversus Abdominis Plane Block|PROCEDURE: External Oblique Intercostal Fascial Plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Two Modes of Mechanical Ventilation for Intensive Care Patients With Low Blood Oxygen Due to Breathing Difficulties
Status: RECRUITING
Conditions: Hypoxic Respiratory Failure|Ventilators, Mechanical
Interventions: OTHER: Airway pressure release ventilation|OTHER: Volumen controlled mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Registration and Assessment of Serious Adverse Events Within the AFNET
Status: COMPLETED
Conditions: Atrial Fibrillation|Assessment of Serious Advers Events|Thromboembolic and Bleeding Complications|Complications of Antiarrhythmic Drugs or Invasive Procedures|Assessment by a Critical Event Committee
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bone Marrow Aspirate Concentrate in Treating Mandibular Cystic Defects
Status: COMPLETED
Conditions: Mandible Cyst
Interventions: OTHER: Enucleation and filling by Bone marrow aspirate|OTHER: Conventional enucleation only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance, Efficacy and Safety of Vibrating Capsule in Aiding Constipated Individuals
Status: COMPLETED
Conditions: Chronic Idiopathic Constipation
Interventions: DEVICE: vibrating capsule|DEVICE: sham non-vibrating capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Rapamycin to Erase Angiofibromas in TSC
Status: COMPLETED
Conditions: Angiofibromas|Tuberous Sclerosis
Interventions: DRUG: Placebo|DRUG: Rapamycin|DRUG: Rapamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of M40403 for the Prevention of Dose Limiting Toxicities of High Dose IL-2
Status: SUSPENDED
Conditions: IL-2 Induced Hypotension
Interventions: DRUG: M40403
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Measuring Abdominal Wall Compliance During Gynecologic Laparoscopic Surgery
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Laparoscopic sacrocolpopexy|PROCEDURE: gynecologic laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multidimensional Evaluation of Patients' Affected by Obstructive Apnea Syndrome (OSAS) Before and After Ventilotherapy
Status: RECRUITING
Conditions: Obstructive Sleep Apnea|Sleep Disorder|Well-Being, Psychological|Cognitive Impairment|Cognitive Change|Neurologic Signs
Interventions: DEVICE: Continuous Positive Airway Pressure Ventilotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Anti-Xa Levels in Surgery Patients Receiving Weight-based Heparin
Status: COMPLETED
Conditions: Deep Vein Thrombosis|Pulmonary Embolism|Venous Thromboembolism
Interventions: DRUG: Standard heparin dose|DRUG: Real time heparin dose adjustment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of an Infectivity Enhanced Suicide Gene Expressing Adenovirus for Ovarian Cancer in Patients With Recurrent Ovarian and Other Selected Gynecologic Cancers
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: GENETIC: Ad5.SSTR/TK.RGD|DRUG: Ganciclovir (GCV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dairy Products and Metabolic Syndrome
Status: COMPLETED
Conditions: Blood Pressure|Metabolic Syndrome X
Interventions: DIETARY_SUPPLEMENT: Gamalost (Norwegian traditional cheese)|DIETARY_SUPPLEMENT: Gouda-type cheese
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Niraparib Rechallenge After Surgery in Ovarian Cancer Patients With Oligometastatic Progression
Status: RECRUITING
Conditions: Ovarian Cancer|Oligometastatic Disease|Serous Ovarian Tumor
Interventions: DRUG: Niraparib oral tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Develop, Implement and Assess Effectiveness of Early Warning Score (EWS) for Moneragala District General Hospital
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: BEHAVIORAL: Training|BEHAVIORAL: Introduce EWS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Povidone-iodine 2% Eye Drop Versus Artificial Tear Drop for Treatment of Adenoviral Keratoconjunctivitis
Status: UNKNOWN
Conditions: Adenoviral Keratoconjunctivitis
Interventions: DRUG: Povidone Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind, Placebo Controlled Study to Assess the Efficacy and Safety of SNP-610 for the Treatment of Patients With Non-alcoholic Steatohepatitis
Status: NOT_YET_RECRUITING
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: SNP-610|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of 2.0mg Lucentis to Treat Polypoidal Choroidal Vasculopathy
Status: COMPLETED
Conditions: Polypoidal Choroidal Vasculopathy
Interventions: DRUG: ranibizumab 0.5 or 2.0 mg/0.05 cc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin for Reduction of Myocardial Damage During Angiography and Its Mechanism Associated With IMR
Status: UNKNOWN
Conditions: Stable Angina|Unstable Angina|Acute Non-ST-segment Elevation Myocardial Infarction
Interventions: DRUG: loading dose atorvastatin|DRUG: conventional dose atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Pharmacodynamics, Safety, and Pharmacokinetics of Pazopanib Drops in Adult Subjects With Neovascular AMD
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: tDCS for Multiple System Atrophy With Cerebellar Feature
Status: UNKNOWN
Conditions: Multiple System Atrophy, Cerebellar Variant (Disorder)
Interventions: DEVICE: transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Titration Study of ABX-1431
Status: COMPLETED
Conditions: Post Herpetic Neuralgia|Diabetic Peripheral Neuropathy|Small Fiber Neuropathy|Post-Traumatic Neuralgia
Interventions: DRUG: ABX-1431|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intermittent Fasting Versus Daily Caloric Restriction for Weight Loss
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Daily Caloric Restriction (DCR)|BEHAVIORAL: Intermittent Fasting (IMF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Exhaled Breath Condensate Hydrogen Peroxide (EBC H2O2) as Measured Using a New Device (Inflammacheck™) in Patients With Interstitial Lung Disease, Lung Cancer and Healthy Volunteers.
Status: COMPLETED
Conditions: Interstitial Lung Disease|Lung Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p