pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Efficacy of Everolimus (Afinitor®) in Chinese Adult Patients With Angiomyolipoma Associated With Tuberous Sclerosis Complex.
Status: COMPLETED
Conditions: Renal Angiomyolipoma
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of ATG-Fresenius Following a Renal Transplantation, Without Corticosteroids
Status: TERMINATED
Conditions: Renal Transplant Rejection
Interventions: DRUG: ATG-Fresenius S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: System Accuracy of the Blood Glucose Monitor for Personal Use JT100
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DIAGNOSTIC_TEST: blood glucose measurement, blood glucose monitor for personal use|DIAGNOSTIC_TEST: blood glucose measurement, laboratory reference device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of VIB7734 for the Treatment of Moderate to Severely Active SLE
Status: COMPLETED
Conditions: Lupus Erythematosus, Systemic
Interventions: DRUG: VIB7734|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety of ABBV-916 and How Intravenous ABBV-916 Moves Through Body and Affects Brain Amyloid Plaque Clearance in Adult Participants (Aged 50-90 Years) With Early Alzheimer's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer's Disease (AD)
Interventions: DRUG: ABBV-916|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcome of GATT Combined With Goniosynechiolysis in Glaucoma Patients With Secondary Synechial Angle Closure.
Status: RECRUITING
Conditions: Glaucoma, Angle-Closure
Interventions: OTHER: Gonioscopy-Assisted Transluminal Trabeculotomy Combined with Goniosynechiolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Robotic Upper-Limb Neurorehabilitation in Chronic Stroke Patient
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Upper extremity robot|OTHER: Traditional Supervised Upper Extremity Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-canceR Early-detection Test in Asymptomatic Individuals (PREVENT)
Status: RECRUITING
Conditions: Cancer|Early Detection of Cancer|Circulating Cell-free DNA
Interventions: DEVICE: OverC multi-cancer detection blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Cortical Plasticity After Motor Cortex Stimulation in Healthy Subject and Chronic Pain Patients
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus (RSV) in Adults ≥60 Years of Age
Status: ACTIVE_NOT_RECRUITING
Conditions: Respiratory Syncytial Virus
Interventions: DRUG: Placebo|DRUG: mRNA-1345
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Cefazolin and Normal Saline Irrigation on Surgical Site Infections (SSIs)
Status: COMPLETED
Conditions: Surgical Site Infections
Interventions: OTHER: Cefazolin irrigation|OTHER: Normal Saline Irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Blueberries, Bananas, Exercise Recovery
Status: COMPLETED
Conditions: Inflammatory Response|Metabolic Disturbance|Immune Suppression
Interventions: DIETARY_SUPPLEMENT: Blueberry|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: banana|DIETARY_SUPPLEMENT: No banana
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Erythropoietin Administration and Stress Responses in Trauma Patients
Status: UNKNOWN
Conditions: Multiple Trauma
Interventions: DRUG: erythropoietin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate THR-687 Treatment for Diabetic Macular Oedema.
Status: TERMINATED
Conditions: Diabetes Mellitus|Diabetic Retinopathy|Diabetic Macular Edema
Interventions: DRUG: THR-687 dose level 1|DRUG: THR-687 dose level 2|DRUG: THR-687 selected dose level|DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Long-Term Proton Pump Inhibitor Use a Cause of Leaky Gut Syndrome
Status: COMPLETED
Conditions: Proton Pump Inhibitor Adverse Reaction
Interventions: DIAGNOSTIC_TEST: Blood for zonulin level was drawn from the group.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bortezomib and Gemcitabine in Treating Patients With Recurrent or Metastatic Nasopharyngeal Cancer
Status: COMPLETED
Conditions: Recurrent Nasopharyngeal Cancer|Stage IV Nasopharyngeal Cancer
Interventions: DRUG: bortezomib|DRUG: gemcitabine hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FGF-23 and Endothelial Dysfunction in Diabetic Proteinuric Patients
Status: COMPLETED
Conditions: Proteinuria|Diabetic Nephropathy|Chronic Kidney Disease
Interventions: DRUG: Ramipril
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Near-Infrared Imaging for Perfusion Assessment of Traumatic Soft Tissue and Skeletal Injuries
Status: RECRUITING
Conditions: Perfusion|Traumatic Injury|Fluorescence Imaging
Interventions: DIAGNOSTIC_TEST: Near-infrared fluorescence imaging of perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Individualized Administration of Warfarin by Polymorphisms of VKORC1 and CYP2C9 Genes
Status: UNKNOWN
Conditions: Heart Valve Prosthesis
Interventions: OTHER: dose regime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mechanism of Delayed Neutrophil Apoptosis in Acute Lung Injury
Status: COMPLETED
Conditions: Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)|Neutrophils|Apoptosis|Immunosuppression|Pathogenesis
Interventions: DRUG: Ocotillol Type Ginsenoside Derivatives
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to Measure Response to Etanercept in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Imaging After Non-traumatic Intracranial Hemorrhage (SAVEBRAINPWI)
Status: RECRUITING
Conditions: Aneurysm, Ruptured|Aneurysmal Subarachnoid Hemorrhage|Arteriovenous Malformations|Intracranial Aneurysm|Intracranial Hemorrhages
Interventions: DIAGNOSTIC_TEST: Brain computed tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Complementary and Alternative Medicine Interventions in Targeting Pain
Status: COMPLETED
Conditions: Quadrantectomies|Spinal Fusion|Carotid Stenosis|Abdominal Aortic Aneurysm|Colectomy
Interventions: BEHAVIORAL: RR intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Study of N-Acetylcysteine to Treat Deliberate Self-Harm in Adolescents
Status: COMPLETED
Conditions: Deliberate Self Harm
Interventions: DIETARY_SUPPLEMENT: N-Acetylcysteine|DRUG: fMRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the Addition of Fluticanse Propionate/Salmeterol (250/50mcg) Twice-daily to 2 Doses of Umeclidinium Bromide (62.5 or 125mcg) Once-daily Over 12 Weeks
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Umeclidinium bromide 62.5mcg|DRUG: Umeclidinium bromide 125mcg|DRUG: Fluticasone propionate 250mcg/Salmeterol 50mcg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tocilizumab in Active Moderate-severe Graves' Orbitopathy
Status: UNKNOWN
Conditions: Graves Ophthalmopathy
Interventions: DRUG: Tocilizumab 20 Mg/mL Intravenous Solution|DRUG: MethylPREDNISolone Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Esophagectomy Pain Control Trial
Status: RECRUITING
Conditions: Postoperative Pain, Acute|Postoperative Complications
Interventions: PROCEDURE: Thoracic epidural catheter|PROCEDURE: Local intercostal nerve block|PROCEDURE: Cryo-analgesia and intercostal nerve block|PROCEDURE: Serratus plane catheter blocks and intercostal nerve blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Virtual Pelvic Floor Physical Therapy With a Pelvic Floor Trainer in the Treatment of Stress Urinary Incontinence.
Status: RECRUITING
Conditions: Stress Urinary Incontinence|Pelvic Floor Disorders
Interventions: DEVICE: Pelex Upp|BEHAVIORAL: Pelvic Floor Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Sham Device Controlled, Single Blinded Trial of Portable Transcutaneous Electrical Nerve Stimulation and Heat Therapy Machine in Women With Dysmenorrhea
Status: UNKNOWN
Conditions: Dysmenorrhea
Interventions: DEVICE: I RUNE|DEVICE: sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of the Next-Generation Intraocular Lenses
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Investigational Intraocular Lens Device #1: Model ZFR00|DEVICE: Investigational Intraocular Lens Device #1: Model ZYR00|DEVICE: TECNIS Multifocal Intraocular Lens: Model ZLB00
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of the Locus Coeruleus in Age-related Distractibility
Status: RECRUITING
Conditions: Aging|Alzheimer Disease
Interventions: BEHAVIORAL: Tablet based adaptive multimodal attention practice program|BEHAVIORAL: Tablet based adaptive criterion task practice program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of DSP-7888 Dosing Emulsion in Combination With Immune Checkpoint Inhibitors in Adult Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Renal Cell Carcinoma (RCC)|Urothelial Carcinoma|Primary Peritoneal Cancer|Platinum-resistant Ovarian Cancer (PROC)|Serous Epithelial Ovarian Cancer|Fallopian Tube Cancer
Interventions: DRUG: DSP-7888 Dosing Emulsion|DRUG: Nivolumab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study in Combination With BMS-790052 and BMS-650032 in Japanese Hepatitis C Virus (HCV) Patients
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: BMS-790052 (Daclatasvir)|DRUG: BMS-650032 (Asunaprevir)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Synchronous and Asynchronous Telerehabilitation in COVID-19 Discharges
Status: COMPLETED
Conditions: COVID-19|Telerehabilitation
Interventions: OTHER: Synchronous telerehabilitation programme|OTHER: Asynchronous telerehabilitation programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluative Conditioning: A Brief Cognitive Intervention Aimed to Modify Addiction Behaviour of Alcohol-dependent Patients
Status: WITHDRAWN
Conditions: Cognitive Intervention to Modify Addiction Behaviour of Alcohol-dependent Patients
Interventions: OTHER: Evaluative Conditionning Task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PREEMPTIVE THERAPY WITH COLCHICINE IN PATIENTS OLDER THAN 60 YEARS WITH HIGH RISK OF SEVERE PNEUMONIAE DUE TO CORONAVIRUS
Status: COMPLETED
Conditions: SARS-CoV-2 Infection (COVID-19)
Interventions: DRUG: Colchicine plus symptomatic treatment (paracetamol)|DRUG: Symptomatic treatment (paracetamol or best symptomatic treatment based on doctor recommendations)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Docetaxel, Irinotecan, and Carboplatin in Extensive Stage Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer|Extensive Stage Unresectable
Interventions: DRUG: Docetaxel|DRUG: Irinotecan|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conservative Versus Operative ManageMent of Acute Uncomplicated Appendicitis
Status: COMPLETED
Conditions: Appendicitis
Interventions: PROCEDURE: Laparoscopic +/- Open Appendicectomy|DRUG: Antibiotic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Escalation Study on Safety and Immunogenicity of VPM1002 in Comparison With BCG in Healthy Male Volunteers
Status: COMPLETED
Conditions: Tuberculosis|Healthy
Interventions: BIOLOGICAL: VPM1002|BIOLOGICAL: BCG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Improving Cerebral Blood Flow and Cognitive Function in Patients With Asymptomatic Intracranial / Carotid Stenosis With Nattokinase (ICC-PACS)
Status: RECRUITING
Conditions: Cerebral Blood Flow|Cognitive Function
Interventions: DRUG: Nattokinase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Status After Single Oral Dose of Cholecalciferol in Low Fat Meal Compared to High-fat Meal
Status: COMPLETED
Conditions: Deficiency, Vitamin D
Interventions: DIETARY_SUPPLEMENT: colecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Four Week, Pharmacodynamic/Pharmacokinetic, Efficacy, and Safety Study of Lunacalcipol (CTA018)
Status: WITHDRAWN
Conditions: Stage 5 Chronic Kidney Disease (CKD)|Secondary Hyperparathyroidism (SHPT)|Hemodialysis (HD)
Interventions: DRUG: Lunacalcipol 180|DRUG: Lunicalcipol 270
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reparative Therapy in Acute Ischemic Stroke With Allogenic Mesenchymal Stem Cells From Adipose Tissue, Safety Assessment, a Randomised, Double Blind Placebo Controlled Single Center Pilot Clinical Trial
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DRUG: Allogenic mesenchymal stem cells from adipose tissue|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Bioavailability Study of Methotrexate 25 mg Administered by Needle Injection and a Pre Filled Needle-free Device in Healthy Volunteers.
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Zeneo® - Methotrexate|DRUG: Methotrexate Biodim®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of RT001 to Treat Moderate to Severe Lateral Canthal Lines
Status: COMPLETED
Conditions: Lateral Canthal Lines
Interventions: OTHER: Vehicle Control|DRUG: RT001 (Botulinum Toxin Type A Topical Gel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study for the Treatment of Knee Chondral and Osteochondral Lesions
Status: COMPLETED
Conditions: Knee Chondral Lesion|Knee Osteochondral Lesion
Interventions: PROCEDURE: Marrow stimulation - Drilling or Microfractures|DEVICE: MaioRegen Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: U-500R Insulin In Type 2 Diabetes With Severe Insulin Resistance Via Omnipod
Status: COMPLETED
Conditions: Type 2 Diabetes|Insulin Resistance
Interventions: DRUG: U-500 Insulin delivered by Omnipod (disposable insulin pump)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Of Training On Brushing Behavior
Status: COMPLETED
Conditions: Orthodontic Appliances|Oral Health Training|Oral Hygiene
Interventions: BEHAVIORAL: Standard Verbal/Written Education|BEHAVIORAL: Video Assisted Education|BEHAVIORAL: Hands-on Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Steady State Kinetics of l-Methamphetamine and Validation of Sensitivity of Dose Estimation
Status: COMPLETED
Conditions: Nasal Congestion
Interventions: DRUG: l-methamphetamine|DRUG: d-methamphetamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multi-center, Randomized to Compare the Efficacy of IVIG Alone and IVIG Plus High-dose Aspirin in Kawasaki Disease
Status: UNKNOWN
Conditions: Kawasaki Disease
Interventions: OTHER: IVIG only|OTHER: IVIG and Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genasense® (Oblimersen Sodium), Fludarabine, and Rituximab in Subjects With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Oblimersen-rituximab-fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gut Microbiota, the Potential Key to Modulating Humoral Immunogenicity of New Platform COVID-19 Vaccines
Status: UNKNOWN
Conditions: Microbiome|Vaccine|Covid-19|SARS-CoV-2|Immunogenicity
Interventions: OTHER: This is observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Trial of Nab-Paclitaxel and Gemcitabine for First-Line Treatment of Patients With Cholangiocarcinoma
Status: COMPLETED
Conditions: Cholangiocarcinoma
Interventions: DRUG: Nab-Paclitaxel and Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cholera-Hospital-Based-Intervention-for-7-days
Status: COMPLETED
Conditions: Cholera|Diarrhea|Stunting
Interventions: BEHAVIORAL: CHoBI7 health facility program|BEHAVIORAL: CHoBI7 mHealth program|BEHAVIORAL: CHoBI7 home visit program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Repetitive Transcranial Magnetic Stimulation in Patients With Peripheral Vestibular Dysfunction
Status: COMPLETED
Conditions: Peripheral Vestibular Dysfunction
Interventions: DEVICE: Repetitive transcranial magnetic stimulation|OTHER: Cawthorne Cooksey exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiotherapy for Hepatocellular Carcinoma, and Intrahepatic Cholangiocarcinoma
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular|Intrahepatic Cholangiocarcinoma
Interventions: RADIATION: Stereotactic radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Study of BCX9930 in Healthy Volunteers and Patients With PNH
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: BCX9930|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Duloxetine for Pain Management After Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Laparoscopic Hysterectomy|Postoperative Recovery|Postoperative Pain
Interventions: DRUG: Duloxetine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Bevacizumab and Ziv-aflibercept in Diabetic Macular Edema
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: DRUG: bevacizumab|DRUG: ziv-aflibercept 1.25 mg|DRUG: ziv-aflibercept 2.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Ex Vivo Expanded Autologous Immune Killer Cells (IKC) in Stage IV Non-small Cell Lung Cancer (NSCLC) in Patients Who Failed Chemotherapy or Target Therapy
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer (NSCLC) Stage IV
Interventions: BIOLOGICAL: Immune Killer Cells (IKC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Posaconazole Dosing Regimen for Paediatric Patients With Cystic Fibrosis and Aspergillus Infection
Status: UNKNOWN
Conditions: Cystic Fibrosis|Aspergillosis
Interventions: DRUG: Posaconazole 100 MG [Noxafil]|DRUG: Posaconazole 40 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Probiotics (P. Pentosaceus, L. Lactis or L. Helveticus) in NASH
Status: UNKNOWN
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: Probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: The Effects of Upper Extremity Aerobic Exercise Training in Patients With Type 2 Diabetes
Status: RECRUITING
Conditions: Type2diabetes
Interventions: OTHER: Upper extremity aerobic exercise training|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Superficial Supportive Psychotherapy Model and Its Effect on Acute Coronary Syndrome Psycho-Neuro-Endocrine Studies
Status: COMPLETED
Conditions: Psychosomatic Disorder
Interventions: BEHAVIORAL: Supportive Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Radiotherapy With or Without Concurrent Chemotherapy for Extensive Lymphatic Metastasis of Esophageal Cancer - 3JECROG P-03
Status: UNKNOWN
Conditions: IMRT With or Without Concurrent Chemotherapy for Esophageal Cancer
Interventions: RADIATION: SIB-IMRT|DRUG: Paclitaxel|DRUG: Platinum-Based Drug|DRUG: Paclitaxel|DRUG: Platinum-Based Drug|OTHER: Involved Field Irradiation (IFI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Anti-PD-1 Antibody and Chemotherapy for Unresectable Intrahepatic Cholangiocarcinoma
Status: UNKNOWN
Conditions: Intrahepatic Cholangiocarcinoma by AJCC V8 Stage
Interventions: DRUG: Combination therapy|DRUG: Mono-chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Transcutaneous Auricular Vagal Nerve Stimulation on Functional Dyspepsia
Status: UNKNOWN
Conditions: Functional Dyspepsia
Interventions: DEVICE: taVNS 10|DEVICE: taVNS 25|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anakinra Versus Placebo for the Treatment of Acute MyocarditIS
Status: COMPLETED
Conditions: Acute Myocarditis
Interventions: DRUG: ANAKINRA 100 mg/daily subcutaneously|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Inspiratory Muscle Warm-Up in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|COPD
Interventions: OTHER: Inspiratory Muscle Warm-up (IMW)|OTHER: Inspiratory Muscle Training (IMT)|OTHER: Respiratory exercises and aerobic exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation Of The Relationship Between Imagery Ability, Balance And Functionality After Stroke
Status: COMPLETED
Conditions: Stroke|Motor İmagery Ability|Mental Chronometry|Balance|Functionality
Interventions: OTHER: Kinesthetic and Visual Imagery Questionnaire, Box and Block Test, Hand Lateralization Test.|OTHER: Berg Balance Scale, Functional Reach Test|OTHER: Timed Up and Go Test, Functional Independence Scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Contribution of Animal-assisted Intervention in Oral Healthcare for Disabled Patients (YODA)
Status: NOT_YET_RECRUITING
Conditions: Autism
Interventions: OTHER: Animal-assisted intervention|BEHAVIORAL: Venham scale modified by Veerkamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Osimertinib With and Without Ramucirumab in Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer|EGFR Gene Mutation|Advanced Cancer|Metastatic Cancer
Interventions: DRUG: Osimertinib|DRUG: Ramucirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Rosuvastatin Therapy in Patients With Stable Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Rosuvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vincristine, Dactinomycin, and Doxorubicin With or Without Radiation Therapy or Observation Only in Treating Younger Patients Who Are Undergoing Surgery for Newly Diagnosed Stage I, Stage II, or Stage III Wilms' Tumor
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage I Kidney Wilms Tumor|Stage II Kidney Wilms Tumor|Stage III Kidney Wilms Tumor
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|PROCEDURE: Biospecimen Collection|PROCEDURE: Chest Radiography|PROCEDURE: Computed Tomography|BIOLOGICAL: Dactinomycin|DRUG: Doxorubicin Hydrochloride|PROCEDURE: Echocardiography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Therapeutic Conventional Surgery|PROCEDURE: Ultrasound Imaging|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Therapeutic Exploratory Clinical Study of DA-8010 in Patients With Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: DA-8010 Placebo|DRUG: DA-8010 2.5mg|DRUG: DA-8010 5mg|DRUG: Solifenacin 5mg|DRUG: Solifenacin succinate placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Clarithromycin on the Pharmacokinetics of Apixaban in Healthy Participants
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Apixaban|DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bypass or Thurpass for Superficial Femoral Artery Occlusion? Scandinavian Thurpass Study
Status: TERMINATED
Conditions: Femoral Artery Occlusion
Interventions: PROCEDURE: Thrupass|PROCEDURE: Bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance of a Single-use Gastroscope (aScope Gastro) for Esophagogastroduodenoscopy
Status: COMPLETED
Conditions: Gastroscopy|Esophagogastroduodenoscopy|Equipment Design|Equipment Contamination / Prevention & Control|Cross Infection / Prevention & Control|Disposable Equipment|Infection Control / Methods
Interventions: DEVICE: Single-use gastroscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clevidipine in the Treatment of Blood Pressure in Patients With Acute Heart Failure (PRONTO)
Status: COMPLETED
Conditions: Hypertension|Heart Failure
Interventions: DRUG: Clevidipine|DRUG: Standard of Care IV antihypertensive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketosis Impact on Signs & Symptoms of Schizophrenia and Bipolar disorderS
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia and Related Disorders|Psychosis|Bipolar and Related Disorders|Manic Episode|Depressive Episode
Interventions: DIETARY_SUPPLEMENT: (R)-3-hydroxybutyl (R)-3-hydroxybutyrate)|OTHER: Maltodextrin, Fructose, Pectin, Sodium alginate, Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Thalidomide in the Treatment of Refractory Uremic Pruritus
Status: UNKNOWN
Conditions: Haemodialysis|Uremic Pruritus|Thalidomide
Interventions: DRUG: Thalidomide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TV-based Service to Support People Living With Mild Dementia or Mild Cognitive Impariment
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Mild Dementia
Interventions: DEVICE: TV-based Assistive Integrated Service
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vitamin D Plus Fluticasone Propionate
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Vitamin D3|DRUG: Placebo|DRUG: Fluticasone Propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: V160 2-Dose and 3-Dose Regimens in Healthy Cytomegalovirus (CMV) Seronegative Females (V160-002)
Status: COMPLETED
Conditions: Cytomegalovirus (CMV) Infections
Interventions: BIOLOGICAL: V160|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Recombinant Leptin Therapy for Treatment of Nonalcoholic Steatohepatitis (NASH)
Status: COMPLETED
Conditions: Fatty Liver Disease, Nonalcoholic
Interventions: DRUG: metreleptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sensitivity of New Exercise Tests in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: ipratropium bromide|DRUG: placebo|BEHAVIORAL: constant rate step test|BEHAVIORAL: constant rate shuttle walk test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Oral Nutritional Supplements Compared With Standard Diet in Postoperative Gastric Cancer Patients With Adjuvant Chemotherapy
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DIETARY_SUPPLEMENT: NutrenOpimum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of F182112 in Patients With Relapsed or Refractory Multiple Myeloma
Status: UNKNOWN
Conditions: Dose-Escalation Study, Relapsed or Refractory Multiple Myeloma
Interventions: DRUG: F182112
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Iontophoresis Versus Injection of Corticosteroids for Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis|Work Related Injury
Interventions: DRUG: dexamethasone to injury site
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sotagliflozin Versus Placebo in Chinese Patients With Type 2 Diabetes Mellitus Not Adequately Controlled by Metformin With or Without Sulfonylurea
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: sotagliflozin (SAR439954)|DRUG: placebo|DRUG: metformin|DRUG: sulfonylurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Efficacy of an Intradiscal Injection of Corticoids in Modic I Discopathies.
Status: COMPLETED
Conditions: Low Back Pain|Lumbago|Modic I Discopathy
Interventions: DRUG: Hydrocortancyl.|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of ABT-126 in Subjects With Mild to Moderate Alzheimer's Disease on Stable Doses of Acetylcholinesterase Inhibitors
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: ABT-126|DRUG: ABT-126|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 3T MR Angiography of the Hepatic Vasculature
Status: TERMINATED
Conditions: Liver Blood Supply
Interventions: DIAGNOSTIC_TEST: Magnetic Resonance Imaging (MRI)|DIAGNOSTIC_TEST: Compurtized Tomgraphy (CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intersphincteric Resection With or Without Intraoperative Radiation in Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: RADIATION: Interoperative radiation by INTRABEAM using low energy X-ray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of TST005 in Patients With Locally Advanced or Metastatic Solid Tumors
Status: TERMINATED
Conditions: Locally Advanced or Metastatic Cancers|Metastatic Human Papillomavirus-Related Malignant Neoplasm
Interventions: DRUG: TST005
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Randomized Trial of Pain Neuroscience Education in the Rehabilitation After Arthroscopic Rotator Cuff Repair
Status: COMPLETED
Conditions: Rotator Cuff Injuries
Interventions: BEHAVIORAL: Pain Neuroscience Education|BEHAVIORAL: Biomedical Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Knee Osteoarthritis With Bone Marrow Aspirate Matrix: Prospective, Randomized Trial
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Bone marrow aspirate matrix|BIOLOGICAL: Bone marrow aspirate|DEVICE: Hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogenic Mesenchymal Stem Cell Intraarticular Injection for Knee Osteoarthritis Therapy
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Allogenic adipose derived mesenchymal stem cells (AD-MSC)|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Beta-glucan Supplement in Chronic Obstructive Pulmonary Disease Patients
Status: NOT_YET_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease Patients
Interventions: DIETARY_SUPPLEMENT: Beta-glucan supplement group|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Observational Pharmacokinetic Sudy of Ceftolozane-Tazobactam in Intensive Care Unit in Patients With and Without CRRT
Status: COMPLETED
Conditions: Gram-Negative Bacterial Infections
Interventions: OTHER: Non CRRT group|OTHER: CRRT group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Multi-disciplinary Treatment of Functional Gut Disorders Study
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Functional Dyspepsia|Constipation - Functional|Faecal Incontinence|Functional Abdominal Pain Syndrome|Other Rome IV Functional Gastrointestinal Disorders
Interventions: OTHER: Multi-disciplinary clinic model|OTHER: Standard outpatient care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Chronic Dosing Cross-Over Study to Assess the Efficacy and Safety of Glycopyrronium (PT001) in Adult Subjects With Intermittent Asthma or Mild to Moderate Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Glycopyrronium MDI|DRUG: Serevent Diskus 50 μg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cervical Sympathetic Block in Patients With Cerebral Vasospasm
Status: ENROLLING_BY_INVITATION
Conditions: Anesthesia, Local|Cerebral Vasospasm|Subarachnoid Hemorrhage, Aneurysmal
Interventions: PROCEDURE: Cervical sympathetic block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunochemotherapy With Rituximab-Bendamustine-Cytarabine (R-BAC) for Patients With Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Mantle-Cell
Interventions: DRUG: Rituximab, Bendamustine, Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing the Radiological Selection and Transfer Model in Stroke Patients Presenting 6-24h After Onset (VESTA Study)
Status: COMPLETED
Conditions: Stroke, Ischemic
Interventions: DIAGNOSTIC_TEST: Multiparametric imaging|DIAGNOSTIC_TEST: Non contrast CT+CT angiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Verification of the Efficacy and Safety of the BAROSTIM NEO System in the Treatment of Drug Resistant Hypertension
Status: ACTIVE_NOT_RECRUITING
Conditions: High Blood Pressure
Interventions: DEVICE: BAROSTIM NEO System|DRUG: Medical Management
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pirfenidone as Treatment of Skin Fibrosis in Systemic Sclerosis
Status: UNKNOWN
Conditions: Systemic Sclerosis
Interventions: DRUG: Pirfenidone|DRUG: Placebo oral capsule|DRUG: Steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability Phase Ia Study of XT1061 in Single and Multiple Doses in Healthy Subjects
Status: RECRUITING
Conditions: Chronic Hepatitis b
Interventions: DRUG: Test drug XT1061 capsules and placebo,Single dose group|DRUG: Test drug XT1061 capsules and placebo，Multiple dosing group|DRUG: Test drug XT1061 capsules and placebo，Food Impact Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors|MSI-H/dMMR Tumors|Cutaneous Squamous Cell Carcinoma|Urothelial Carcinoma, HCC|Cervical Cancer|Esophageal Squamous Cell Carcinoma|Merkel Cell Carcinoma|Small-cell Lung Cancer|Mesothelioma|PD-L1 Amplified Tumor (9p24.1)|Nasopharyngeal Carcinoma|Cyclin-dependent Kinase 12 Mutated Tumors|Basal Cell Carcinoma (Unresectable or Metastatic)|Sarcomatoid Renal Cell Carcinoma|Clear Cell Ovarian or Endometrial Carcinoma|Anal Carcinoma|Squamous Cell Penile Carcinoma|DNA Polymerase Epsilon Mutated Tumors (P286R and V411L)
Interventions: DRUG: INCB099318
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Atezolizumab in Combination With Carboplatin or Cisplatin + Pemetrexed Compared With Carboplatin or Cisplatin + Pemetrexed in Participants Who Are Chemotherapy-Naive and Have Stage IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC) (IMpower 132)
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Atezolizumab|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medicare Anti-Aβ mAb Coverage With Evidence Development (CED) Study
Status: RECRUITING
Conditions: Mild Alzheimer's Disease|Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease
Interventions: DRUG: Monoclonal Antibodies Directed Against Amyloid for the Treatment of Alzheimer's Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Comparing Monthly Boniva (Ibandronate) and Weekly Risedronate in Women With Post-Menopausal Osteoporosis.
Status: COMPLETED
Conditions: Post Menopausal Osteoporosis
Interventions: DRUG: Risedronate|DRUG: ibandronate [Bonviva/Boniva]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Photobiomodulation Therapy Combined With Static Magnetic Field in Patients With Lateral Epicondylitis
Status: UNKNOWN
Conditions: Lateral Epicondylitis
Interventions: DEVICE: Active PBMT-sMF|DEVICE: Placebo PBMT-sMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effectiveness and Safety of SHR-1314 for Psoriatic Arthritis
Status: UNKNOWN
Conditions: Psoriatic Arthritis
Interventions: DRUG: SHR-1314 injection|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lasers in Peri-implantitis Treatment
Status: COMPLETED
Conditions: Peri-Implantitis
Interventions: DEVICE: Laser ,Fotona, Light Walker AT, Ljubljana, Slovenia|DRUG: Mechanical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT