pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of Safety and Effectiveness of Lobster Dynamic Interspinous Spacer in Lumbar Spinal Stenosis
Status: RECRUITING
Conditions: Spinal Lumbar Stenosis|Claudication, Intermittent
Interventions: DEVICE: Lobster Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Quality of Life and Changes Experienced by Patients After Epilepsy Surgery
Status: RECRUITING
Conditions: Epilepsy
Interventions: OTHER: Epilepsy Surgery Satisfaction Questionnaire (ESSQ-19)|OTHER: Quality of Life in Epilepsy Inventory (QOLIE-31)|OTHER: Generalized Anxiety Disorder 7 (GAD7)|OTHER: Neurological Disorders Depression Inventory for Epilepsy (NDDI-E)|OTHER: Evaluation of Changes in Daily Life after Epilepsy Surgery (EVOCQUE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nintedanib in Volunteers With Hepatic Impairment Compared With Healthy Volunteers
Status: COMPLETED
Conditions: Hepatic Insufficiency
Interventions: DRUG: Nintedanib|DRUG: Nintedanib|DRUG: Nintedanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polymorphisms in CD36 and STAT3 Genes and Different Dietary Interventions Among Patients With Coronary Artery Disease
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DIETARY_SUPPLEMENT: Olive oil|DIETARY_SUPPLEMENT: Nuts|DIETARY_SUPPLEMENT: Control diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Platelet Rich Plasma on Pain at Skin Graft Donor Sites
Status: TERMINATED
Conditions: Skin Graft (Allograft) Rejection|Skin Graft Complications|Skin Graft Detachment|PRP
Interventions: PROCEDURE: PRP harvest and preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Electroacupuncture in Patients With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DEVICE: Electroacupuncture treatment (electrical stimulation machine (EY-3308 Model, G6805-2 Mayfair))|DEVICE: Sham acupuncture treatment (electrical stimulation machine (EY-3308 Model, G6805-2 Mayfair))
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Acetazolamide on Optic Nerve Sheath Diameter in Laparoscopic Donor Nephrectomies
Status: COMPLETED
Conditions: Intracranial Pressure Increase
Interventions: DRUG: Acetazolamide|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention of Metabolic Acidosis in Preterm Neonates by Replacing Sodium Chloride With Sodium Acetate in Parenteral Nutrition
Status: RECRUITING
Conditions: Metabolic Acidosis|Neonatal Disease|Neonatal Complication
Interventions: DRUG: sodium acetate group will receive sodium acetate in the neonatal PN.|DRUG: sodium chloride group will receive sodium chloride in the neonatal PN.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Pre-procedural PCR and Culture-based UTI Assessment Prior to Intravesical Botox Injection
Status: WITHDRAWN
Conditions: Urinary Tract Infections
Interventions: DIAGNOSTIC_TEST: Multiplex-PCR with Pooled Antibiotic Susceptibility Testing (M-PCR/P-AST)|DIAGNOSTIC_TEST: Urine Culture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study to Assess Lung Shunting of Yttrium-90 Microspheres Using PET/CT
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Adult Primary Liver Cancer|Liver Metastases|Localized Unresectable Adult Primary Liver Cancer|Recurrent Adult Primary Liver Cancer
Interventions: PROCEDURE: positron emission tomography|PROCEDURE: computed tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Consolidative Involved-site Radiotherapy for Patients With Limited-stage Diffuse Large B-cell Lymphoma
Status: RECRUITING
Conditions: Diffuse Large B-cell Lymphoma
Interventions: RADIATION: Consolidation involved-site radiotherapy (ISRT)|RADIATION: Consolidation involved-field radiotherapy (IFRT)|DRUG: cyclophosphamide|DRUG: doxorubicin|DRUG: vincristine|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-986263 in Healthy Participants
Status: COMPLETED
Conditions: Fibrosis
Interventions: DRUG: BMS-986263|OTHER: Placebo|DRUG: Diphenhydramine|DRUG: Famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Risk Stratification-directed NAC for Prevention of Poor Hematopoietic Reconstitution
Status: ACTIVE_NOT_RECRUITING
Conditions: Stem Cell Transplant Complications
Interventions: DRUG: N-acetyl-L-cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Parenteral Nutrition in Patients With Biliopancreatic Mass Lesions
Status: COMPLETED
Conditions: Weight Loss|Pancreatic Cancer|Biliary Tract Cancer
Interventions: DIETARY_SUPPLEMENT: Olimel Peri 2.5% ®|DIETARY_SUPPLEMENT: Isotonic fluid (E153)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Brief Integrative Alcohol Interventions for Adolescents
Status: WITHDRAWN
Conditions: Alcohol Abuse|Drug Abuse
Interventions: BEHAVIORAL: Brief Prevention Program Using Positive Image|BEHAVIORAL: Brief Prevention Program Using Positive Image|BEHAVIORAL: Brief Prevention Program Using Positive Image|BEHAVIORAL: Brief Prevention Program Using Positive Image
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Chlorhexidine and/or Betadine Prep in Pediatric Arm Surgery Following Trauma
Status: TERMINATED
Conditions: Arm Fracture|Surgical Site Infection
Interventions: DRUG: Chlorhexidine|DRUG: Betadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Remote Ischemic Preconditioning in Cardiac Surgery Trial
Status: COMPLETED
Conditions: Cardiac Surgery
Interventions: PROCEDURE: Remote Ischemic Preconditioning|PROCEDURE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Case Control Study of Vascular Function in Cyclists
Status: UNKNOWN
Conditions: Endothelial Function and Arterial Stiffness
Interventions: OTHER: flow mediated dilation (endothelial function)|OTHER: ABPI|OTHER: Pulse wave velocity and augmentation index|OTHER: blood pressure|OTHER: ramp test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Specified Drug-Use Survey of Alogliptin and Metformin Hydrochloride Combination Tablets "Survey on Long-term Use in Type 2 Diabetes Mellitus Patients With Renal or Hepatic Impairment or Advanced Age"
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Alogliptin and Metformin hydrochloride
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2 Study to Evaluate the Cardiac and Renal Effects of Short Term Treatment With Elamipretide in Patients Hospitalized With Congestion Due to Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: elamipretide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Convalescent Plasma for Treatment of COVID-19 Patients With Pneumonia
Status: COMPLETED
Conditions: Corona Virus Infection|SARS-CoV 2|SARS Pneumonia|Pneumonia
Interventions: DRUG: High-Titer Anti-SARS-CoV-2 (COVID 19) Convalescent Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutrition Education Intervention in Adults With Type 2 Diabetes Mellitus in a Resource Poor Setting
Status: COMPLETED
Conditions: Diabetes Mellitus, Type II [Non-insulin Dependent Type] [NIDDM Type] Uncontrolled
Interventions: BEHAVIORAL: Nutrition education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: The Microbiological Assessment of Deep Carious Lesions After Step-wise Excavation and Diode Laser Cavity Disinfection .
Status: UNKNOWN
Conditions: Antibacterial Effect of Diode Laser
Interventions: DEVICE: diode laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: First-in-human Study of ATR Inhibitor BAY1895344 in Patients With Advanced Solid Tumors and Lymphomas
Status: COMPLETED
Conditions: Advanced Solid Tumor|Non-Hodgkin's Lymphoma|Mantle Cell Lymphoma
Interventions: DRUG: Elimusertib (BAY1895344)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Platform to Screen Healthcare Workers- Coordinated Approach to Pandemic Trials of COVID-19
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthcare Worker|Covid19
Interventions: DIAGNOSTIC_TEST: Nasopharyngeal swab|OTHER: Questionnaire collection|OTHER: Optional blood completion|OTHER: Optional questionnaire completion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca 6)
Status: TERMINATED
Conditions: Colorectal Cancer|Triple Negative Breast Cancer|Pancreatic Cancer|Non-Small Cell Lung Cancer|Head and Neck Cancer|Ovarian Cancer|Lymphoma|Sarcoma|Bladder Cancer|Melanoma|IDH1 Mutated Solid Tumors|IDH1 Mutated or MGMT Methylated Recurrent HGG (Not Recruiting)
Interventions: BIOLOGICAL: Toca 511|DRUG: Toca FC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microenvironment and Immunity of Digestive Cancers - East Paris Multicentric Cohort
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Pancreas Tumor|Biliary Tract Tumor|Immune System and Related Disorders
Interventions: BIOLOGICAL: Tumor samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intraoperative Echocardiography in Low-Risk CABG Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Heart Diseases|Coronary Artery Disease|Chest Pain|Stenosis Coronary|STEMI
Interventions: DEVICE: TEE probe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: S1011 Standard or Extended Pelvic Lymphadenectomy in Treating Patients Undergoing Surgery for Invasive Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: PROCEDURE: therapeutic conventional surgery|PROCEDURE: therapeutic standard lymphadenectomy|PROCEDURE: therapeutic extended lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extended Mesenteric Excision in Ileocolic Resections for Crohn's Disease.
Status: UNKNOWN
Conditions: Crohn Disease|Recurrence|Crohn's Ileocolitis
Interventions: PROCEDURE: Extended mesenteric resection.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Minimization of Bleeding Related Adverse Drug Events in Plastic & Reconstructive Surgery
Status: COMPLETED
Conditions: Venous Thromboembolism|Deep Venous Thrombosis|Pulmonary Embolus|Reconstructive Surgery
Interventions: DRUG: Fixed dose|DRUG: Variable dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Electrical Stimulation of the Paretic Upper Limb in the Early Stroke Phase
Status: COMPLETED
Conditions: Stroke, Acute
Interventions: OTHER: Continuous, suprasensory ESS|OTHER: Intermittent, suprasensory ESS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Glucose Homeostasis in Type 2 Diabetes: the Effects of Saccharose
Status: COMPLETED
Conditions: Type 2 Diabetes|Glycemic Control
Interventions: DIETARY_SUPPLEMENT: Sucrose consumption|DIETARY_SUPPLEMENT: water consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Probiotics for the Prevention of Antibiotic-Associated Diarrhea
Status: TERMINATED
Conditions: Acute Diarrhea
Interventions: DIETARY_SUPPLEMENT: Probiotic (BioK+)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Low-CArbohydrate Diet and SGLT2-INhibitOr to Achieve Moderate Ketosis in Healthy Volunteers
Status: RECRUITING
Conditions: Ketones, Metabolism
Interventions: DRUG: SGLT2 inhibitor|OTHER: Controlled, Adaptive Study Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: BE Study of Once Daily PMR Compared to Twice Daily Cilostazol Tablets in Healthy Volunteers
Status: COMPLETED
Conditions: Intermittent Claudication
Interventions: DRUG: Cilostazol Tablet 100 mg|DRUG: PMR Tablet 145 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Anxiety Problems Among Children Indicated to Have Developmental Language Disorder
Status: RECRUITING
Conditions: Developmental Language Disorder and Language Impairment|Anxiety Disorders and Symptoms
Interventions: BEHAVIORAL: Adapted Cognitive Behavioural|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: State Immunization Information Systems to Improve HPV Vaccination Rates
Status: COMPLETED
Conditions: Vaccine|Human Papiloma Virus Vaccine|HPV Vaccine|Immunization|Health Registry|Adolescent Health|Reproductive Health|Preventive Health Services
Interventions: OTHER: Vaccine Reminder/Recall
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Thrombectomy and Improvement of Left Ventricular Function in AMI
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Ventricular Remodeling
Interventions: DEVICE: Export catheter (Medtronic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Innovative Strategy to Offer Online Test and Treat for Thai MSM/TG
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: OTHER: Group A: Offline HTC|OTHER: Group B1: Offline HIV testing and post-test counseling|OTHER: Group B2: Online HIV testing and post-test counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: DFD01 Spray vs Comp01 Lotion HPA Axis Suppression Study in Patients With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: DFD01 Spray|DRUG: Comp01 Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Secondary Prevention of Depression Through Group-based ACT-Therapy Preceded by an Experimental ABM-Procedure
Status: COMPLETED
Conditions: Major Depression
Interventions: BEHAVIORAL: Attention Bias Modification|BEHAVIORAL: Sham Attention Bias Modification|BEHAVIORAL: Acceptance and Commitment Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Single Rotary File System Versus Conventional Manual K-file in Pulpectomy of Primary Molars.
Status: NOT_YET_RECRUITING
Conditions: Endodontically Treated Teeth
Interventions: PROCEDURE: single file rotary|PROCEDURE: Conventional Manual K files
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Computerized Tool (PAINRelieveIt) to Help Manage Pain Related to Sickle Cell Disease
Status: COMPLETED
Conditions: Anemia, Sickle Cell|Hemoglobin SC Disease
Interventions: BEHAVIORAL: PAINReportIt|BEHAVIORAL: PAINUCope|BEHAVIORAL: PAINConsultN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Methotrexate Followed by Fludarabine in Patients With T-Cell Large Granular Lymphocytic Leukemia
Status: TERMINATED
Conditions: T-Cell Large Granular Lymphocytic Leukemia
Interventions: DRUG: MTX followed by fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irinotecan Combined With Cisplatin as 1st Line Treatment for Esophageal Squamous Cell Cancer : a Single Center Prospective Clinical Trial
Status: UNKNOWN
Conditions: Advanced Esophageal Squamous Carcinoma
Interventions: DRUG: irinotecan/cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Progressive Modular Rebalancing (RMP) System Rehabilitation Combined With Sensory Cues for Rehabilitation of Patients With PD
Status: COMPLETED
Conditions: Parkinson Disease|Movement Disorders
Interventions: OTHER: Treatment A combined exercise program and gait training with sensory cues|OTHER: Treatment B Conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Action Observation Therapy on Pain and Brain Hemodynamics in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis|Action Observation Therapy|Functional Near Infared Spectroscopy|Exercise
Interventions: OTHER: Action observation therapy|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-marketing Evaluation of Reactions Following Receipt of Recommended Adolescent Pertussis Vaccine
Status: COMPLETED
Conditions: Pertussis|Diphtheria|Tetanus|Poliomyelitis
Interventions: BIOLOGICAL: COVAXIS™: Tetanus, diphtheria, acellular 5-component pertussis, or + inactivated poliovirus vaccine (REPEVAX®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Safety and Efficacy of Patients With Four and More Symptomatic Brain Metastases of Melanoma
Status: TERMINATED
Conditions: Metastatic Melanoma|Brain Metastases
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Hoodia Gordonii for Treatment of Non Alcoholic Fatty Liver Disease (NAFLD)
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: Hoodia gordonii|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PooR Embryo Yield Cleavage Stage Versus blaStocyst Embryo Transfer (PILOT STUDY)
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: day 3 uterine transfer|PROCEDURE: day 5 uterine transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Brepocitinib in Adults With Active Non-Infectious Non-Anterior Uveitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-infectious Intermediate Uveitis|Non-infectious Posterior Uveitis|Non-infectious Pan Uveitis
Interventions: DRUG: Brepocitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Arsenic Trioxide Plus Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma
Status: COMPLETED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma
Interventions: DRUG: arsenic trioxide|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Generic Delayed-Release Dimethyl Fumarate (Sclera® or Marovarex ®, Hikma) in Routine Medical Practice in the Treatment of Relapsing-Remitting Multiple Sclerosis in MENA Region
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: Dimethyl Fumarate (DMF)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Investigational Combination Vaccine Given to People Who Are Not Infected With HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Combination Vaccine (NefTat and gp120W61D) Formulated with AS02A|BIOLOGICAL: NefTat|DRUG: AS02A Adjuvant|BIOLOGICAL: gp120W61D
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Investigation of the Effect of Motor Imagery Training in Individuals With Cervical Discogenic Pain
Status: RECRUITING
Conditions: Image, Body|Neck Pain|Disc Herniation
Interventions: OTHER: Motor Imagery Exercises|OTHER: Motor Control Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lenalidomide Combined With Azacitidine vs Azacitidine in the Treatment of MDS-RS
Status: NOT_YET_RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Lenalidomide|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reiki and Qi-gong Therapy to Improve Negative Emotional States of Anxiety, Depression, and Stress in Type-2 Diabetics
Status: RECRUITING
Conditions: Type-2 Diabetic Patients
Interventions: BEHAVIORAL: Reiki Therapy|BEHAVIORAL: Qi-gong Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Elevated Plasma-Free-Fatty-Acids on Renal Hemodynamic Parameters
Status: COMPLETED
Conditions: Renal Circulation|Renal Plasma Flow|Glomerular Filtration Rate|Fatty Acids, Nonesterified
Interventions: DRUG: NG-monomethyl-L-Arginine (L-NMMA)|DRUG: triglycerides (Intralipid 20%)|DRUG: heparin|DRUG: somatostatin|DRUG: insulin|DRUG: glucose|DRUG: inulin|DRUG: paraamino hippurate (PAH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Impact of Good Practice Guidelines on Evidence-based Practice and Nurses' Work Environment
Status: COMPLETED
Conditions: Nurses' Work Environment|Committed Centers With Excellence in Care (CCEC®) Program|Nurses' Evidence-based-practice Attitudes|Nurse Physician Relations|Practice Nurse's Scope|Professional Stress
Interventions: OTHER: Good Practice Guidelines implementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Peripheral Histamine 1 Receptor Blockade in IBS: Multicenter Trial
Status: COMPLETED
Conditions: Irritable Bowel Syndrome (IBS)
Interventions: DRUG: Ebastine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ABT-652 in Combination With a Nonsteroidal Anti-Inflammatory Drug (NSAID) in Adults With Osteoarthritis Pain of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: ABT-652 NSAID|DRUG: Placebo NSAID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2/3 Dose-Ranging Study of the Safety and Efficacy of OTX-101 in the Treatment of Keratoconjunctivitis Sicca
Status: COMPLETED
Conditions: Keratoconjunctivitis Sicca|Dry Eye Disease
Interventions: DRUG: OTX-101 0.05%|DRUG: OTX-101 0.09%|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Chest Wall Mobilization Program in Improving Respiratory Function for Patients With COPD
Status: UNKNOWN
Conditions: COPD
Interventions: OTHER: Chest Wall Mobilization Program|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stimulant vs. Non-stimulant Treatments and Reward Processing in Drug-naive Youth at SUD Risk
Status: RECRUITING
Conditions: ADHD|Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Methylphenidate|DRUG: Atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Bristle-less Toothbrush (PeriClean) on Gum Recession
Status: COMPLETED
Conditions: Gingival Recession
Interventions: OTHER: Tooth brush without nylon bristles|OTHER: Tooth brush with soft nylon bristles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Role of Pollen Starch Granules in Pollen Challenge Studies in the Fraunhofer Environmental Exposure Unit
Status: COMPLETED
Conditions: Asthma|Seasonal Allergic Rhinitis
Interventions: PROCEDURE: exposure to grass pollen/starch granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Anlotinib Hydrochloride Capsules in the Treatment of Locally Advanced or Metastatic Radioiodine-Refractory Differentiated Thyroid Carcinoma
Status: RECRUITING
Conditions: Thyroid Neoplasms
Interventions: DRUG: Anlotinib Hydrochloride Capsule
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Therapy With Asunaprevir, Daclatasvir, Ribavirin and Pegylated Interferon Alpha-2a in HCV Genotype 4-infected Patients Who Have Failed to a Previous Therapy With Peg-Interferon/Ribavirin (ANRS HC32 QUATTRO)
Status: COMPLETED
Conditions: Hepatitis C Virus Genotype 4 Infection
Interventions: DRUG: Asunaprevir|DRUG: Daclatasvir|DRUG: Ribavirin|DRUG: Pegylated Interferon alpha-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Neuraxial Position Technique " The Anatolian Sitting Position- Sitting Fetal Cross-legged"
Status: COMPLETED
Conditions: Anesthesia, Conduction
Interventions: PROCEDURE: The SFP technique|PROCEDURE: The ASP technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Hexadecasaccharide (SR123781A) in Patients With Unstable Angina or Non-ST-Segment Elevation Myocardial Infarction
Status: COMPLETED
Conditions: Coronary Atherosclerosis
Interventions: DRUG: Hexadecasaccharide (SR123781A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Modulating Temporoparietal Junction Mentalizing-Related Activity in Autism Spectrum Disorder (ASD) Using Transcranial Magnetic Stimulation (TMS)
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DIAGNOSTIC_TEST: fMRI|DEVICE: rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Quetiapine Augmentation of PE Therapy for the Treatment of Co-occurring PTSD and Mild Traumatic Brain Injury
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: DRUG: Quetiapine Fumarate|OTHER: Standard of care meducations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Imatinib in Combination With High Dose Chemotherapy for Acute Phase Chronic Myelogenous Patients
Status: TERMINATED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Imatinib mesylate 600 mg|DRUG: Cytarabine|DRUG: Daunorubicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mycotoxin Exposure and Dietary Habits in Colorectal Cancer Prevention and Development Among Polish Population
Status: UNKNOWN
Conditions: Colorectal Cancer, Somatic (Diagnosis)
Interventions: PROCEDURE: colonoscopy|OTHER: questionnaires|OTHER: demographic data collections|OTHER: anthropometric data collections|PROCEDURE: Collecte the biological samples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Sorafenib (Nexavar) in Combination With Gemcitabine in Advanced Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Sorafenib and Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Gingival Health Following Rubber-Dam Isolation
Status: RECRUITING
Conditions: Gingival Recession, Localized
Interventions: OTHER: Hu-Friedy 212 clamp|OTHER: dental floss using the simple knot tie method|OTHER: Coltene B4 clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Project LIFT - Promoting Healthy Behavior Through a Wearable Fitness Device and Financial Incentives
Status: COMPLETED
Conditions: Kidney Transplant; Complications|Liver Transplant; Complications|Obesity
Interventions: BEHAVIORAL: Self-monitoring of physical activity with incentives|BEHAVIORAL: Usual care and self-monitoring of physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effectiveness of At-home , In-office and Combined Dental Bleaching System ：A Randomized Controlled Clinical Trial
Status: COMPLETED
Conditions: Tooth Bleaching
Interventions: PROCEDURE: different combined of tooth bleaching procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: KAND567 Versus Placebo in Subjects Hospitalized With COVID-19
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: KAND567|DRUG: Microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Panitumumab Efficacy in Patients With Recurrent and/or Metastatic Head and Neck Cancer
Status: COMPLETED
Conditions: Recurrent and/or Metastatic Head and Neck Cancer
Interventions: DRUG: ARM 2|DRUG: ARM 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Salvia Hispanica-Enriched Foods on Glycemic and Insulinemic Responses and Subjective Satiety
Status: COMPLETED
Conditions: Post Prandial Blood Glucose
Interventions: DIETARY_SUPPLEMENT: White Bread|DIETARY_SUPPLEMENT: White bread with added 7.32g Salvia hispanica|DIETARY_SUPPLEMENT: White bread with added 15.58g Salvia hispanica|DIETARY_SUPPLEMENT: White bread with added Salvia hispanica|DIETARY_SUPPLEMENT: Rice milk|DIETARY_SUPPLEMENT: Enriched rice milk containing 7.32g Salvia hispanica|DIETARY_SUPPLEMENT: Enriched rice milk containing 15.58g Salvia hispanica|DIETARY_SUPPLEMENT: Enriched rice milk containing 24g Salvia hispanica
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD)
Status: TERMINATED
Conditions: Major Depressive Disorder (MDD)
Interventions: DRUG: Escitalopram|DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells
Status: RECRUITING
Conditions: Metastatic Prostate Adenocarcinoma With Neuroendocrine Differentiation|Metastatic Prostate Neuroendocrine Carcinoma|Metastatic Prostate Small Cell Neuroendocrine Carcinoma|Stage IV Prostate Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|RADIATION: Gallium Ga 68-DOTATATE|DRUG: Lutetium Lu 177 Dotatate|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rwanda Vaginal Microbiota Restoration Study
Status: COMPLETED
Conditions: Bacterial Vaginosis
Interventions: BIOLOGICAL: Vaginal multiple lactobacilli-containing probiotic for prevention of BV recurrence|DRUG: Prophylactic use of metronidazole pills (500 mg)|BIOLOGICAL: Vaginal Lcr35-containing probiotic for prevention of BV recurrence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pregabalin Versus Celecoxib on Sevoflurane and Analgesic Consumption in Spine Fixation Surgery
Status: COMPLETED
Conditions: Post-Operative Pain
Interventions: DRUG: Celecoxib capsules|DRUG: Pregabalin 150mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IG vs ID Bitter Administration
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Intragastric quinine hydrochloride|DRUG: Intragastric denatonium benzoate|DRUG: Intragastric placebo|DRUG: Intraduodenal quinine hydrochloride|DRUG: Intraduodenal denatonium benzoate|DRUG: Intraduodenal placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Acipimox on Insulin Action, Vascular Function, and Muscle Function in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Acipimox|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Two-period Crossover Study to Demonstrate the Comparability of Pharmacokinetics of Subcutaneous Ianalumab Between 2mL Auto-injector/2mL PFS with1mL Pre-filled Syringe in Adult Participants With Autoimmune Disease
Status: RECRUITING
Conditions: Sjögrens Disease|Systemic Lupus Erythematosus|Rheumatoid Arthritis
Interventions: BIOLOGICAL: VAY736 1ml PFS|BIOLOGICAL: VAY736 2 ml PFS|BIOLOGICAL: VAY736 2ml AI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Automated Oxygen Control by O2matic to Patients Admitted With Acute Hypoxemia
Status: RECRUITING
Conditions: Hypoxemic Respiratory Failure|Hypoxia|Hypoxemia|Respiratory Failure|Respiratory Insufficiency
Interventions: DEVICE: O2matic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Metastatic Malignant Neoplasm in the Brain|Recurrent Non-Small Cell Lung Carcinoma|Stage IV Non-Small Cell Lung Cancer AJCC v7
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|DRUG: Erlotinib Hydrochloride|RADIATION: Stereotactic Radiosurgery|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telmisartan vs. Perindopril in Mild-Moderate Alzheimer's Disease Patients
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: DRUG: Perindopril|DRUG: Telmisartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cortical Excitability Changes on the Sensorimotor Cortex Induced by Caffeine Consumption: A TMS Study
Status: COMPLETED
Conditions: Cortical Excitability|Brain Stimulation
Interventions: COMBINATION_PRODUCT: Caffeine_TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: inDividual, Targeted thrombosIS Prophylaxis Versus the Standard 'One Size Fits All' Approach in Patients Undergoing Total hIp or Total kNee replaCemenT
Status: NOT_YET_RECRUITING
Conditions: Venous Thromboembolism|Venous Thromboses|Pulmonary Embolism|Deep Vein Thrombosis
Interventions: OTHER: Short duration prophylaxis|OTHER: Higher intensity and longer duration prophylaxis|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Single and Multiple Dose Pharmacokinetics of Sufentanil NanoTab
Status: COMPLETED
Conditions: Plasma Concentrations
Interventions: DRUG: Single dose of SUF NT 15 mcg|DRUG: 40 consecutive doses of SUF NT 15 mcg taken every 20 minutes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Longterm Safety Study of BEMA Buprenorphine in Subjects With Chronic Pain
Status: COMPLETED
Conditions: Pain|Low Back Pain|Osteoarthritis|Neuropathic Pain
Interventions: DRUG: BEMA Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Heel Offloading Devices for Reducing Heel Contact Pressures in Healthy Volunteers
Status: COMPLETED
Conditions: Heel Pressure Ulceration Prevention Strategies
Interventions: OTHER: Pillow Condition 1|OTHER: Pillow Condition 2|DEVICE: Heel Foam Pillow|DEVICE: Offloading Device A|DEVICE: Offloading Device B|DEVICE: Offloading Device C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Masitinib Combined With Isoquercetin and Best Supportive Care in Hospitalized Patients With Moderate and Severe COVID-19
Status: RECRUITING
Conditions: SARS-CoV 2|COVID-19|Coronavirus Disease 2019
Interventions: DRUG: Masitinib|DRUG: Isoquercetin|DRUG: Best Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Albumin-bound Paclitaxel Combined With Liposomal Doxorubicin in the Treatment of Advanced or Unresectable Angiosarcoma
Status: RECRUITING
Conditions: Angiosarcoma Metastatic
Interventions: DRUG: Abraxane combined with liposomal doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and HAART to Treat AIDS-related Primary Brain Lymphoma
Status: COMPLETED
Conditions: AIDS-Related-Primary Central Nervous System Lymphoma
Interventions: DRUG: Methotrexate|DRUG: Rituximab|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Pyronaridine-Artesunate Versus Artemether-Lumefantrine
Status: COMPLETED
Conditions: Malaria Fever|Plasmodium Falciparum Malaria|Uncomplicated Malaria
Interventions: DRUG: Antimalarials, pyronaridine-artesunate|DRUG: Antimalarials, Artemether + Lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Donepezil on Deficits Associated With Age-Related Decrease of Growth Hormone
Status: COMPLETED
Conditions: Elderly
Interventions: DRUG: Donepezil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Dutasteride in Combination With CAB vs CAB in SDC
Status: RECRUITING
Conditions: Salivary Duct Carcinoma
Interventions: DRUG: Goserelin 10.8 mg|DRUG: Bicalutamide 50 mg|DRUG: Dutasteride 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Intravenous Tissue Plasminogen Activator Treatment Algorithm of Nursing Intern Students
Status: COMPLETED
Conditions: Acute Stroke
Interventions: BEHAVIORAL: theory training|BEHAVIORAL: theory and simulation training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Digital Memory Notebook
Status: ENROLLING_BY_INVITATION
Conditions: Prodromal Alzheimer's Disease|Mild Cognitive Impairment|Subjective Cognitive Complaints
Interventions: BEHAVIORAL: Digital Memory Notebook (DMN) Application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Prospective Investigation of the ColubrisMX ELS System
Status: COMPLETED
Conditions: Colorectal Neoplasms|Colorectal Polyp|Colorectal Adenoma|Colorectal Adenomatous Polyp
Interventions: DEVICE: Robotic Endoluminal Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Upper Airway Stimulation on Vascular Function in Obstructive Sleep Apnea
Status: TERMINATED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Hypoglossal Nerve Stimulation Treatment Withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery and/or Radiation Therapy or Standard Therapy and/or Clinical Observation in Treating Patients With Previously Treated Stage IV Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Lung Non-Small Cell Carcinoma|Stage IV Non-Small Cell Lung Cancer AJCC v7
Interventions: OTHER: Clinical Observation|RADIATION: External Beam Radiation Therapy|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|PROCEDURE: Standard Follow-Up Care|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Treatment of Irritable Bowel Syndrome (IBS)
Status: RECRUITING
Conditions: IBS - Irritable Bowel Syndrome
Interventions: BEHAVIORAL: Module 1|BEHAVIORAL: Module 2|BEHAVIORAL: Module 3|BEHAVIORAL: Module 4|BEHAVIORAL: Module 5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: #BabyLetsMove Physical Activity Feasibility Trial
Status: COMPLETED
Conditions: Pregnancy Related|Adolescent Obesity|Behavior, Health|Behavior, Sedentary|Adolescent Overweight|Mobile Phone Use|Pregnancy in Adolescence
Interventions: BEHAVIORAL: #BabyLetsMove
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: My Cardiac Recovery (MyCaRe): A Pilot RCT.
Status: RECRUITING
Conditions: Postoperative; Dysfunction Following Cardiac Surgery
Interventions: OTHER: MyCaRe (my cardiac recovery Android application)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of 3D Machine-vision Image Guided Surgery Spine Navigation
Status: COMPLETED
Conditions: Spinal Stenosis, Lumbar Region|Spondylolisthesis
Interventions: DEVICE: 3D MvIGS Spine Navigation|OTHER: 2D Fluoroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT