pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Hesperidin on Bone Mineral Density and Bone Metabolism of Postmenopausal Women
Status: COMPLETED
Conditions: Osteoporosis, Osteopenia
Interventions: DRUG: Hesperidin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Umbilical Cord Blood Transplantation In Patients With Hematologic Malignancies Using A Myeloablative Preparative Regimen
Status: COMPLETED
Conditions: Hematologic Malignancies|Disorder Related to Transplantation|Hematopoietic Malignancy
Interventions: DRUG: Preparative Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantitative GLP-1 Receptor Imaging Correlated to ex Vivo Distribution of In-111-exendin
Status: TERMINATED
Conditions: Diabetes Mellitus
Interventions: RADIATION: indium-111-exendin SPECT/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PPI Guided Strategies for Prevention and Treatment of Intraoperative Hypotension
Status: RECRUITING
Conditions: Intraoperative Hypotension
Interventions: BEHAVIORAL: PPI guided strategies|BEHAVIORAL: Empirical strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multipolar CRT-d and Diabetes
Status: COMPLETED
Conditions: Diabetes|Heart Failure|Heart Failure NYHA Class II|Heart Failure NYHA Class III
Interventions: DEVICE: Multipolar CRT-d, plus conventional drug therapy for HF.|DEVICE: Bipolar CRT-d, plus conventional drug therapy for HF.|DRUG: HF drugs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trauma-focused Psychodynamic Psychotherapy for LGBT Patients With Post-traumatic Stress Disorder
Status: COMPLETED
Conditions: Complex Post-Traumatic Stress Disorder|Post-traumatic Stress Disorder
Interventions: BEHAVIORAL: Trauma-focused psychodynamic psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy Dose Complement in the Treatment of Hypoxic Lesions Patients With Stage III Non-small-cell Lung Cancer
Status: UNKNOWN
Conditions: Stage III Non-small-cell Lung Cancer
Interventions: RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Diclofenac Potassium and Propolis in the Therapy of Oral Aphthosis
Status: COMPLETED
Conditions: Oral Mucositis|ORAS|Oral Infection|Oral Ulcer
Interventions: COMBINATION_PRODUCT: Combination of diclofenac potassium and propolis|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Using Allogenic-Cytomegalovirus (CMV) Specific Cells for Glioblastoma Multiforme (GBM)
Status: TERMINATED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|BIOLOGICAL: CMV Specific Cytotoxic T Lymphocytes (CTL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Gingival Massage of Aloe-vera Gel and Sidr Honey on Chronic Periodontitis
Status: COMPLETED
Conditions: Gingival Massage|Chronic Periodontitis
Interventions: OTHER: Aloe-vera gel|OTHER: sidr honey|PROCEDURE: Scaling ans root Debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lombardi Comprehensive Cancer Center/Legacy Pilot Study to Reduce Adverse Smoking Outcomes in the Context of Lung Cancer Screening
Status: COMPLETED
Conditions: Smoking|Lung Cancer
Interventions: BEHAVIORAL: Telephone Counseling|BEHAVIORAL: Minimal Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability, Pharmacokinetics, and Immunogenicity Study of CNTO 6785 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo IV|DRUG: CNTO 6785 1 mg/kg IV|DRUG: CNTO 6785 3 mg/kg IV|DRUG: CNTO 6785 10 mg/kg IV|DRUG: CNTO 6785 SC|DRUG: Placebo SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of Simtuzumab (GS-6624) in Adults With Idiopathic Pulmonary Fibrosis (IPF)
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Simtuzumab|DRUG: Simtuzumab placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of House Dust Mite Allergen Challenge in Persons Using 1200 mg Gamma Tocopherol Supplements
Status: COMPLETED
Conditions: Allergic Rhinitis|Mild Asthma
Interventions: DRUG: Gamma Tocopherol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thromboprophylaxis in Patients Undergoing Orthopedic Surgeries; Comparison Between Rivaroxaban and Enoxaparin
Status: UNKNOWN
Conditions: Thromboses, Deep Vein|Surgery--Complications
Interventions: DRUG: Rivaroxaban 10 Milligrams|DRUG: Enoxaparin 40 Milligrams/0.4 Milliliters Prefilled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Analysis of HBV-Specific Immune Response in Patients With HBeAg Negative Chronic Hepatitis B Treated With Pegasys (Peginterferon Alfa-2a (40KD)) - Immunology Sub-Study of ML18253
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: peginterferon alfa-2a [Pegasys]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Propionate for Reduction of LDL Cholesterol
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Calcium-Propionate 500mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing eTEP and Laparoscopic Intraperitoneal Onlay Mesh (IPOM) for Ventral Hernias
Status: COMPLETED
Conditions: Ventral Hernia|Umbilical Hernia|Epigastric Hernia
Interventions: PROCEDURE: Ventral Hernia Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between ESPB Versus IV Morphine as Postoperative Analgesia After Spine Surgeries .
Status: NOT_YET_RECRUITING
Conditions: Discectomy|Vertebral Fractures
Interventions: DRUG: Erector Spinae plane block (plain pubivicaine)|DRUG: Intravenous morphine group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Genetically Modified Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas
Status: WITHDRAWN
Conditions: Adult Anaplastic Astrocytoma|Adult Anaplastic Oligodendroglioma|Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Tumor
Interventions: BIOLOGICAL: carboxylesterase-expressing allogeneic neural stem cells|DRUG: irinotecan hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ramucirumab (IMC-1121B) With Paclitaxel and Carboplatin in Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: BIOLOGICAL: Ramucirumab|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility, Acceptability, and Fidelity of Motivational Interviewing to Increase Maternal NICU Presence
Status: COMPLETED
Conditions: Neonatal Intensive Care
Interventions: BEHAVIORAL: Motivational Interviewing|OTHER: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long-Term Safety and Antibody Persistence of TDV and the Impact of a Booster Dose
Status: COMPLETED
Conditions: Dengue Fever
Interventions: BIOLOGICAL: Takeda's Dengue Tetravalent Vaccine (Live, Attenuated) (TDV)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combined Colloids And Crystalloids Versus Crystalloids in Women With Preeclampsia Undergoing Cesarean Delivery
Status: COMPLETED
Conditions: Pre-Eclampsia|Cesarean Section
Interventions: PROCEDURE: Spinal Anesthesia|DRUG: Intrathecal Bupivacaine|DRUG: Intrathecal Fentanyl|PROCEDURE: Cesarean Delivery|RADIATION: Ultrasound Assessment of the Inferior Vena Cava|DRUG: 250 mL Colloid over 5 minutes|DRUG: 250 mL Crystalloid over 5 minutes|DRUG: 500 mL Crystalloid over 55 minutes|DRUG: 250 mL Colloid over 60 minutes|DRUG: 250 mL Crystalloid over 60 minutes|DRUG: Intravenous Ephedrine|DRUG: Intravenous Syntocinon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib Phosphate and Chemotherapy Given Before and After Reduced Intensity Donor Stem Cell Transplant in Treating Patients With Myelofibrosis
Status: COMPLETED
Conditions: Primary Myelofibrosis|Secondary Myelofibrosis
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Fludarabine|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan|OTHER: Pharmacological Study|DRUG: Ruxolitinib|DRUG: Ruxolitinib Phosphate|DRUG: Sirolimus|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic and Headache-Inducing Effect of Intravenous Vasoactive Intestinal Peptide in Migraineurs
Status: COMPLETED
Conditions: Headache|Migraine|Vasoactive Intestinal Peptide|Ultrasonography, Doppler, Transcranial
Interventions: DRUG: Vasoactive intestinal peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Discovering the Effect of Venous Insufficiency on Nocturia
Status: COMPLETED
Conditions: Nocturia|Venous Insufficiency of Leg|Fluid Overload
Interventions: OTHER: Questionnaires|DIAGNOSTIC_TEST: Frequency Volume Chart|DIAGNOSTIC_TEST: Collect urine during 1 day|DIAGNOSTIC_TEST: Blood sample|DIAGNOSTIC_TEST: Measurement of the circumference of the lower legs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility Controlled Trial of Tibial Nerve Stimulation for Stroke Related Urinary Incontinence
Status: COMPLETED
Conditions: Stroke|Urinary Incontinence
Interventions: DEVICE: NeuroTrac continence stimulators|DEVICE: NeuroTrac continence stimulators
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Functional and Cognitive Impairment Prevention for Elderly Hospitalized Patients
Status: UNKNOWN
Conditions: Functional Impairment|Cognitive Impairment|Elderly
Interventions: OTHER: Group-based exercise training during hospitalization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Rationale and Design of the InsightPFA Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Arrhythmias, Cardiac|Paroxysmal Atrial Fibrillation
Interventions: DEVICE: Pulsed Field Ablation (PFA) Therapy|DEVICE: Radiofrequency Ablation（RAF）Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Diode Laser on Post-operative Pain After Endodontic Treatment in Teeth With Apical Periodontitis
Status: COMPLETED
Conditions: Apical Periodontitis|Postoperative Pain
Interventions: DEVICE: Medency Primo Diode Laser Device (Medency, Vicenza, Italy)|PROCEDURE: 2.5% NaOCl, %17 EDTA, Distilled water, 30-gauge, side-opening needle (Canal Clean, Biodent, South Korea),
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance of a Hydrophilic and a Hydrophobic Intraocular Lens of Similar Design
Status: WITHDRAWN
Conditions: Cataract
Interventions: DEVICE: Hydrophobic IOL|DEVICE: Non-hydrophobic IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Pharmacodynamic Study of Glufast Tablets 10mg(Mitiglinide)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Liver Dysfunction
Interventions: DRUG: Mitiglinide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga-DOTA-NOC PET/CT in Patients With Idiopathic Pulmonary Fibrosis
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: PROCEDURE: 68Ga-DOTA-NOC PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lux-Breast 3; Afatinib Alone or in Combination With Vinorelbine in Patients With Human Epidermal Growth Factor Receptor 2 (HER2) Positive Breast Cancer Suffering From Brain Metastases
Status: COMPLETED
Conditions: Breast Neoplasms|Neoplasm Metastasis
Interventions: DRUG: Vinorelbine|DRUG: Investigator's choice of treatment|DRUG: afatinib|DRUG: afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sunitinib for Metastatic Renal Cell Cancer With Imaging Biomarker Assessments for the Early Prediction of Tumor Response
Status: COMPLETED
Conditions: Renal Cell Cancer
Interventions: DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of Malignant Ascites Caused by Advanced Epithelial Solid Tumors With M701 Bispecific Antibody
Status: RECRUITING
Conditions: Malignant Ascites
Interventions: DRUG: M701|PROCEDURE: paracentesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryoballoon Targeting Atrial Fibrosis in Atrial Fibrillation
Status: WITHDRAWN
Conditions: Atrial Fibrillation|Left Atrial Fibrosis
Interventions: DEVICE: Cryoballoon Ablation: PVI + substrate modification
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caregiver Burden and Depression: Caring for Those Who Care for Others
Status: COMPLETED
Conditions: Dementia|Alzheimer's Disease
Interventions: BEHAVIORAL: UCF Caregiver Support Group|BEHAVIORAL: Community Support Groups
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Humoral and Cell Mediated Immunity and Safety of MF59C.1-adjuvanted Subunit Influenza Vaccine or a Conventional Subunit Influenza Vaccine in Previously Unvaccinated Healthy Subjects
Status: COMPLETED
Conditions: Seasonal Influenza|Influenza|Influenza Due to Unspecified Influenza Virus|Human Influenza
Interventions: BIOLOGICAL: MF59C.1-adjuvanted subunit influenza vaccine|BIOLOGICAL: Sub unit, Inactivated, Influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Middle East "Stepping Forward" Project (MESF)
Status: UNKNOWN
Conditions: Cerebral Palsy|Poststroke/CVA Paresis
Interventions: DEVICE: Chaotic Perturbation|DEVICE: Dummy not active shoes|DEVICE: Treadmill training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Chinese Newly Diagnosed Participants With Philadelphia Chromosome-Positive (Ph+) Chronic Myeloid Leukemia in Chronic Phase (CML-CP)
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia|Philadelphia Chromosome|Chronic Myeloid Leukemia in Chronic Phase
Interventions: OTHER: Non-Interventional
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab
Status: ACTIVE_NOT_RECRUITING
Conditions: Unresectable Hepatocellular Carcinoma
Interventions: DRUG: Atezolizumab|DRUG: Lenvatinib|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluid Dairy Products Consumed Before and Within a Pizza Meal on Glycemic Response, Food Intake and Satiety in Children
Status: COMPLETED
Conditions: Diabetes Prevention|Obesity Prevention
Interventions: OTHER: Dietary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sling vs No Sling After Reverse Total Shoulder Arthroplasty
Status: RECRUITING
Conditions: Shoulder Disease|Rotator Cuff Tear Arthropathy|Shoulder Osteoarthritis
Interventions: OTHER: Time of Sling Use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Myocardial Infarction, COmbined-device, Recovery Enhancement Study
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Coronary Artery Disease|Acute Coronary Syndrome|Myocardial Infarction
Interventions: DEVICE: Corrie Health Digital Platform
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of BGB-30813 Alone or in Combination With Tislelizumab in Participants With Advanced or Metastatic Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: BGB-30813|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Busulfan, Melphalan, and Thiotepa Followed By a Donor Stem Cell Transplant in Treating Patients With High-Risk Ewing's Tumors
Status: COMPLETED
Conditions: Sarcoma
Interventions: BIOLOGICAL: graft versus host disease prophylaxis/therapy|DRUG: busulfan|DRUG: melphalan|DRUG: thiotepa|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety, Tolerability, and Efficacy of Ustekinumab for Symptomatic Gastrointestinal Inflammation Associated With Common Variable Immunodeficiency
Status: COMPLETED
Conditions: Gastrointestinal Inflammation Associated With CVID|CVID Enteropathy
Interventions: BIOLOGICAL: Stelara (ustekinumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Herniectomy Versus Herniectomy With a Spinal Stabilization System for the Treatment of Complex Disc Disease
Status: COMPLETED
Conditions: Sciatica|Back Pain
Interventions: DEVICE: DIAM™ Spinal Stabilization System|PROCEDURE: Herniectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Patients With Primary Breast Diffuse Large B-cell Lymphoma
Status: COMPLETED
Conditions: Large B Cell Diffuse Lymphoma
Interventions: DRUG: Rituximab|PROCEDURE: Prophylactic intrathecal chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate ATP-induced Pain and ATP-induced Dermal Vasodilation by Iontophoresis (0000-118)(COMPLETED)
Status: COMPLETED
Conditions: Osteoarthritis Pain
Interventions: PROCEDURE: Comparator: Iontophoresis and Laser Doppler with ATP|PROCEDURE: Comparator: Iontophoresis and Laser Doppler with Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Direct Left Ventricular Rapid Pacing Via the Valve Delivery Guide-wire in TAVI
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: pacing catheter|DEVICE: valve delivery guidewire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy of Prokinetics With Split Dose of PEG in Morning Colonoscopic Bowel Preparation
Status: COMPLETED
Conditions: Colonoscopy|Bowel Preparation
Interventions: DRUG: itopride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prosthesis Loosening Imaging With Dual Energy and Tomosynthesis
Status: COMPLETED
Conditions: Hip Prosthesis Imaging
Interventions: PROCEDURE: Standard arthrography|PROCEDURE: Dual energy arthrography|PROCEDURE: Arthro-tomosynthesis|PROCEDURE: Arthro-tomography|PROCEDURE: Surgery on painful prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of the Effects of High-dose N-acetylcysteine (NAC) in Idiopathic Pulmonary Fibrosis (IPF)
Status: COMPLETED
Conditions: Pulmonary Fibrosis
Interventions: DRUG: n-acetylcysteine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Micronized Fenofibrate on Fasting and Postprandial Lipoproteins, Inflammatory Mediators and Thrombosis
Status: COMPLETED
Conditions: Hypertriglyceridemia With the Metabolic Syndrome
Interventions: DRUG: Fenofibrate (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Dental Implant Surface Characteristics on Immunological and Microbiological Parameters
Status: COMPLETED
Conditions: Peri-implant Mucositis|Peri-Implantitis
Interventions: OTHER: PICF, Perio-paper®|OTHER: Subgingival Plaque, Hu-Friedy®|OTHER: Williams probe, PCPNU-15 Hu-Friedy®|OTHER: Demographic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Azilsartan in Patients With Diabetic Kidney Disease and Hypertension
Status: RECRUITING
Conditions: Proteinuria|Kidney Dysfunction|Blood Pressure|Diabetic Kidney Disease
Interventions: DRUG: Azilsartan|DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine in Deep Brain Stimulation (DBS) Surgery
Status: COMPLETED
Conditions: Deep Brain Stimulation
Interventions: DRUG: Ketamine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endovascular Embolization for Chronic Subdural Hematomas Following Surgical Evacuation
Status: RECRUITING
Conditions: Chronic SDH and the Efficacy of Embolization
Interventions: PROCEDURE: Craniotomy only|PROCEDURE: Craniotomy + Endovascular embolization of the middle meningeal vessels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Prototype Lenses With Experimental UV/HEV Blocker
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: TRP-200|DEVICE: JJVC Marketed Contact Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Iron Absorption From GDS Capsules
Status: COMPLETED
Conditions: Iron Deficiency
Interventions: DIETARY_SUPPLEMENT: GDS, no meal|DIETARY_SUPPLEMENT: GDS, meal|DIETARY_SUPPLEMENT: control, no meal|DIETARY_SUPPLEMENT: control, meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ProMRI Study of the Entovis Pacemaker System (Phase B)
Status: COMPLETED
Conditions: Magnetic Resonance Imaging (MRI); Cardiac Pacing
Interventions: DEVICE: Patients with a ProMRI Pacemaker System|OTHER: Magnetic Resonance Imaging (MRI) scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Deaf Weight Wise: Community-engaged Implementation Research to Promote Healthy Lifestyle Change With Deaf American Sign Language Users
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Lifestyle|Overweight|Obesity|Cardiovascular Risks|Implementation Research
Interventions: BEHAVIORAL: Deaf Weight Wise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Baricitinib (LY3009104) in Participants From 1 Year to Less Than 18 Years Old With Systemic Juvenile Idiopathic Arthritis (sJIA)
Status: RECRUITING
Conditions: Systemic Juvenile Idiopathic Arthritis
Interventions: DRUG: Baricitinib|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Protective Efficacy of Pb(PfCS@UIS4)
Status: COMPLETED
Conditions: Malaria,Falciparum|Plasmodium Falciparum|Plasmodium Berghei|Controlled Human Malaria Infection (CHMI)
Interventions: BIOLOGICAL: Pb(PfCS@UIS4)-infected mosquitoes|OTHER: Challenge infection P. falciparum
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Chemotherapy With Myocet/Taxotere/Herceptin for HER2 Positive Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Myocet|DRUG: Taxotere|DRUG: Herceptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate The Safety And Efficacy Of ILV-094 In Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Placebo|DRUG: ILV-094|DRUG: ILV-094|OTHER: Placebo|DRUG: ILV-094
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liraglutide as add-on to Insulin in Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: Liraglutide|DRUG: Placebo|DRUG: Liraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Semi-solid Feeding After Percutaneous Endoscopic Gastrostomy (PEG) on the Incidence of Aspiration Pneumonia and Postoperative Length of Stay
Status: COMPLETED
Conditions: Gastrostomy|Aspiration Pneumonia
Interventions: DIETARY_SUPPLEMENT: Semi-solid feed (Terumo PG soft)|DIETARY_SUPPLEMENT: Liquid feed (Meibalance)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ET-blockade and Exercise Induced Blood Flow in T2DM
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Bosentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of RC118 Plus Toripalimab in Patients With Locally Advanced Unresectable or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: RC118|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrative Cognitive-Affective Therapy for Binge Eating Disorder
Status: COMPLETED
Conditions: Binge Eating Disorder
Interventions: BEHAVIORAL: Integrative Cognitive-Affective Therapy|BEHAVIORAL: CBT-Guided Self Help
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of the Transcutaneous Electrical Stimulation Medical Device's Safety and Effectiveness in Treating the Patients With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DEVICE: Transcutaneous pulsed electrical stimulation (NuEyne 02)|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Diagnostic Methods and Dietary Treatment of Diabetic Gastroparesis
Status: COMPLETED
Conditions: Diabetic Gastroparesis
Interventions: DIETARY_SUPPLEMENT: dietary treatment: food of small particle size|RADIATION: Validate X-ray diagnostic method.|OTHER: Can the motility be improved|BIOLOGICAL: postprandial plasma glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Genetic Predictors of Benefit to Pembrolizumab
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Pembrolizumab|DRUG: Carboplatin|DRUG: Nab-paclitaxel|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Muscle Metabolic Function
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: vitamin D|OTHER: aerobic training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Utilization of Autologous Mesenchymal Cells in Posterolateral Spinal Fusion in Degenerative Spine Disease
Status: TERMINATED
Conditions: Degenerative Disc Disease
Interventions: DRUG: Suspension of human autologous MSC 3P in 1.5 ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbohydrate and Metabolism: a Pilot Study
Status: COMPLETED
Conditions: Infant|Metabolism
Interventions: OTHER: Formula with lactose|OTHER: Formula with maltodextrins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluating the Effectiveness of Colon Preparation for Endoscopy Using Specialized Clinical Nutrition
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: Nutridrink 200 ml|DIETARY_SUPPLEMENT: Nutridrink compact protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Autologous Platelet-Rich Plasma Cream for Photoaging and Chronological Skin Aging
Status: UNKNOWN
Conditions: Chronological Aging of Skin|Photoaging of Skin
Interventions: BIOLOGICAL: Platelet Rich Plasma Cream|BIOLOGICAL: Placebo - Sterile Water Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: PD-L1 Inhibitor Combined With Apatinib as First-line Maintenance Treatment for Extensive-stage Small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Small Cell Lung Cancer Extensive Stage
Interventions: DRUG: PD-L1 inhibitor combined with apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oxcarbazepine on Serum Brain Derived Neurotrophic Factor (BDNF) in Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Oxcarbazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cartography and Quantitative Characterization of Achilles Tendon Fibrocartilage by TE = 0ms Imaging at 3T MRI
Status: COMPLETED
Conditions: Spondyloarthropathy|Tendinopathy
Interventions: DEVICE: MRI ZTE2 sequence
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: graft-versus-tumor induction therapy|DRUG: cyclophosphamide|DRUG: melphalan|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Calcaneocuboid Arthrodesis in Triple Arthrodesis by Plate Versus Screw: Randomized Controlled Trial
Status: RECRUITING
Conditions: Calcaneocuboid Osteoarthritis Secondary to Trauma
Interventions: PROCEDURE: Calcaneocuboid arthrodesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human Interleukin-7 (CYT107) to Promote T-Cell Recovery After Cord Blood Transplantation
Status: WITHDRAWN
Conditions: Umbilical Cord Blood Transplant
Interventions: DRUG: CYT107
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab + Paclitaxel + Capecitabine in Triple Negative Metastatic Breast Cancer
Status: TERMINATED
Conditions: Triple Negative Metastatic Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Bevacizumab|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety and Efficacy of sc Pasireotide in Patients With Dumping Syndrome
Status: COMPLETED
Conditions: Postoperative Dumping Syndrome
Interventions: DRUG: Pasireotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FMT to Eradicate Intestinal Colonization by Carbapenem-resistant Enterobacteriaceae
Status: NOT_YET_RECRUITING
Conditions: Enterobacteriaceae Infections|Multi-antibiotic Resistance
Interventions: BIOLOGICAL: Donor - FMT|OTHER: Placebo FMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine Whether Urinary PGE-M Levels Correlate With Ulcerative Colitis Disease
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: PROCEDURE: Urinary PGEm level|PROCEDURE: fecal calprotectin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Once a Day Topical Treatment for Athlete's Foot Fungus Inbetween the Toes in Males and Females
Status: UNKNOWN
Conditions: Tinea Pedis|Athlete's Foot|Foot Fungus|Ringworm
Interventions: DRUG: Sertaconazole nitrate cream 2%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Subclinical Paroxysmal Nocturnal Hemoglobinuria and PNH in the Setting of Another Bone Marrow Failure Syndromes(PNH-2013)
Status: UNKNOWN
Conditions: Paroxysmal Nocturnal Hemoglobinuria|Hemoglobinuria|Hemoglobinuria, Paroxysmal|Proteinuria|Urination Disorders|Thrombosis|Bone Marrow Failure|Aplastic Anemia,|Anemia, Hemolytic
Interventions: DRUG: Levamisole+cyclosporin A+Glucocorticoids|DRUG: cyclosporin A+Glucocorticoids|DRUG: Glucocorticoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs)
Status: RECRUITING
Conditions: Viral Infection|Primary Immune Deficiency Disorder
Interventions: BIOLOGICAL: BK CTL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of PRP (Platelet Rich Plasma) Following Arthroscopic Microfracture of Chondral Lesions of the Hip
Status: WITHDRAWN
Conditions: Femoroacetabular Impingement|Chondral Lesions
Interventions: BIOLOGICAL: Platelet-rich plasma (PRP)|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Noninferiority RCT Comparing Operative vs Nonoperative Treatment for ER-stress Positive Weber-B Unimalleolar Fractures
Status: ACTIVE_NOT_RECRUITING
Conditions: Lateral Malleolus Fracture
Interventions: PROCEDURE: Non-operative treatment|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of Two Inotuzumab Ozogamicin Doses in Relapsed/ Refractory Acute Lymphoblastic Leukemia Transplant Eligible Patients
Status: COMPLETED
Conditions: Leukemia|Precursor b-Cell Lymphoblastic Leukemia-Lymphoma|ACUTE LYMPHOBLASTIC LEUKEMIA
Interventions: DRUG: inotuzumab ozogamicin-dose level 2|DRUG: Inotuzumab ozogamicin-dose level 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment Of Inlay Retained Bridge Designs In Missing Posterior Teeth Cases. (Randomized Clinical Trial)
Status: UNKNOWN
Conditions: Tooth Loss
Interventions: PROCEDURE: tub shaped inlay bridge design
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Saline vs Hypertonic Serum With Respiratory Physiotherapy in a Recurrent Wheezing Patient
Status: UNKNOWN
Conditions: Bronchiolitis
Interventions: OTHER: Hypertonic solution|OTHER: Physiological solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Tigecycline Versus Imipenem/Cilastatin in Hospital-Acquired Pneumonia
Status: COMPLETED
Conditions: Bacterial Pneumonia
Interventions: DRUG: Tigecycline|DRUG: Imipenem|DRUG: Cilastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Use Of Three Commercial Preparations Of Injectable Hyaluronic Acid In Hands Rejuvenation
Status: COMPLETED
Conditions: Injuries to the Wrist and Hand
Interventions: DRUG: Emervel® Touch|DRUG: Emervel® Volume Lidocaine and Emervel® Deep Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Biochemical Markers to Determine the Acetylsalicylic Acid Chemopreventive Effect Through Antiplatelet Action
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Acetylsalicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine (GSK1437173A) When Co-administered With GSK Biologicals' Diphtheria, Tetanus and Pertussis Vaccine (Boostrix®) in Adults Aged 50 Years and Older
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Herpes Zoster vaccine GSK 1437173A|BIOLOGICAL: Boostrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Ticagrelor on Endothelial Function
Status: COMPLETED
Conditions: Coronary Artery Disease|Endothelial Function
Interventions: DRUG: clopidogrel|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: DNR and AraC Combined to Fractionated Mylotarg® in Patients With First Relapse of AML
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Mylotarg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Women With Stage III Breast Cancer
Status: SUSPENDED
Conditions: Breast Cancer
Interventions: DRUG: CAF regimen|DRUG: CMF regimen|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: fluorouracil|DRUG: methotrexate|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Trial of Tocilizumab in ALS Subjects
Status: COMPLETED
Conditions: ALS|Amyotrophic Lateral Sclerosis|Lou Gehrig's Disease|Motor Neuron Disease
Interventions: DRUG: Tocilizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Pharmacokinetics and Safety of BAT3306 Injection Versus KEYTRUDA® Administered in Healthy Male Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Male Subjects
Interventions: DRUG: Recombinant Humanized Anti-PD-1 Monoclonal Antibody Solution for Injection|DRUG: Pembrolizumab injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Safety and Efficacy of Obinutuzumab, Polatuzumab Vedotin (Pola), and Atezolizumab (Atezo) in Participants With Relapsed or Refractory Follicular Lymphoma (FL) and Rituximab, Atezo, and Pola in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Atezolizumab [TECENTRIQ]|DRUG: Obinutuzumab|DRUG: Polatuzumab Vedotin|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Possible Action of Resveratrol in Improving the Outcomes of IVF/ICSI in Couples With Unexplained Infertility
Status: RECRUITING
Conditions: Unexplained Infertility
Interventions: DIETARY_SUPPLEMENT: Resveratrol-based multivitamin supplement|DIETARY_SUPPLEMENT: Folic acid|PROCEDURE: IVF/ICSI|DRUG: Follitropin Alfa|DRUG: Ganirelix Acetate 0.5 MG/ML [Fyremadel]|DRUG: hCG 10.000 IU or triptorelin 0,3 mg, subcutaneously
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Does Social Buffering Continue to be Effective Over the Peripubertal Period When Friends Share the Stressor Experience?
Status: RECRUITING
Conditions: Adolescent Behavior|Social Stress
Interventions: OTHER: Questionnaires|OTHER: TSST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Validation of the "ExSpiron©" in Patients With ALS
Status: NOT_YET_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis|Neuromuscular Diseases
Interventions: DEVICE: ExSprion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Extracorporeal Shock Wave Therapy (ESWT) and Low Intensity Laser Therapy (LLLT) Added to Complete Decongestive Therapy (CDT) on Extremity Volume, Pain Intensity, Functional Status and Quality of Life in Patients With Postmastectomy Stage 2 Lymphedema
Status: COMPLETED
Conditions: Lymphedema, Breast Cancer
Interventions: OTHER: Complete Decongestive Therapy|DEVICE: ESWT|DEVICE: LLLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serratus Anterior Muscle Plane Block vsThoracic Paravertebral Block For Unilateral Mastectomies
Status: WITHDRAWN
Conditions: Breast Cancer|Mastectomy|Regional Anesthesia|Post Operative Pain
Interventions: DRUG: Lidocaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Different Multiple Doses of BI 207127 BID and Multiple Doses of BI 207127 Combined With Faldaprevir in Healthy Male and Female Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 207127 + faldaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT