pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Efficacy of Vilazodone in Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Vilazodone|DRUG: Placebo to citalopram|DRUG: Placebo to vilazodone|DRUG: Citalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of White Potatoes on Glycemic Response, Satiety and Food Intake in Children
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: White bread|OTHER: Baked potato with skin|OTHER: Mashed potato served hot|OTHER: Fried French fries|OTHER: Meal skipping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Reinsertion Achilles Tendon VS Zadek Osteotomy in Insertional Achilles Tendinopathy
Status: NOT_YET_RECRUITING
Conditions: Insertional Achilles Tendinopathy
Interventions: PROCEDURE: Reinsertion achilles tendon|PROCEDURE: Zadek osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Optimum Treatment for Drug-Resistant Hypertension
Status: UNKNOWN
Conditions: Hypertension, Resistant to Conventional Therapy
Interventions: DRUG: Spironolactone|DRUG: Bisoprolol|DRUG: Doxazosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma
Status: TERMINATED
Conditions: Adult Anaplastic Astrocytoma|Adult Anaplastic Oligodendroglioma|Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Adult Mixed Glioma|Recurrent Adult Brain Neoplasm
Interventions: DRUG: Vorinostat|RADIATION: Stereotactic Radiosurgery|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy Strategies for Use in Combined Treatment of Small-cell Lung Cancer
Status: RECRUITING
Conditions: Small Cell Lung Carcinoma
Interventions: RADIATION: Palliative Radiotherapy|RADIATION: Radical/Ablative Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Booster Effect of DTaP-IPV-Hep B-PRP~T Combined Vaccine or Infanrix Hexa™ and Prevenar™ in Healthy Infants
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Whooping Cough|Hepatitis B|Poliomyelitis
Interventions: BIOLOGICAL: DTaP-IPV-Hep B-PRP~T combined vaccine + Pneumococcal polysaccharide|BIOLOGICAL: DTaP-Hep B-IPV // Hib Vaccine + Pneumococcal polysaccharide|BIOLOGICAL: DTaP-IPV-Hep B-PRP~T + Pneumococcal polysaccharide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Early Kangaroo Mother Care in Gambian Hospitalised Unstable Neonates
Status: TERMINATED
Conditions: Preterm Infant|Hypothermia, Newborn|Death|Kangaroo Mother Care|Infection, Bacterial
Interventions: OTHER: Early Kangaroo Mother Care|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Erector Spinae Plane Blocks for Rib Fractures
Status: TERMINATED
Conditions: Rib Fractures|Trauma|Anesthesia|Anesthesia, Local
Interventions: DRUG: Active ropivacaine 0.3% erector spinae plane perineural administration|DRUG: Placebo erector spinae plane perineural administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: One Year Drug Treatment in First-Episode Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Haloperidol, Risperidone (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy, Immunogenicity and Safety of the Inactivated SARS-CoV-2 Vaccine (COVID-19)
Status: COMPLETED
Conditions: COVID-19 Virus Infection
Interventions: BIOLOGICAL: Inactivated SARS-CoV-2 vaccine (Vero cell)|BIOLOGICAL: Placebo/Aluminum Adjuvant of Inactivated SARS-CoV-2 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Concurrent Vestibular Activation and Postural Training Using Virtual Reality
Status: RECRUITING
Conditions: Vestibular Disorder
Interventions: DEVICE: Vestibular training using VR followed by Control|DEVICE: Control followed by Vestibular training using VR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Brivaracetam as add-on Treatment in Adolescents and Adults Suffering From Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Placebo|DRUG: Brivaracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cost Effectiveness of Combined Contingency Management and Cognitive Behavioral Therapy for Alcohol Use Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Drinking|Veterans
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy (CBT)|BEHAVIORAL: Mobile Contingency Management (mCM)|BEHAVIORAL: Long-term incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATT Compared With ATE in OSAS Children
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome in Children
Interventions: PROCEDURE: Adenotonsillectomy|PROCEDURE: Adenotonsillotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody Plus Interleukin-2 in Treating Patients With Leukemia or Lymphoma
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: daclizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: What is in Fact the Contribution of Reducing Time Spent in Sedentary Behaviors on Daily Energy Expenditure? A Doubly Labeled Water Study
Status: COMPLETED
Conditions: Risk Reduction Behavior
Interventions: BEHAVIORAL: Reduction of sedentary time by breaking it with low intensity physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Na-ASP-2 Human Hookworm Vaccine in Healthy Adults Without Evidence of Hookworm Infection
Status: COMPLETED
Conditions: Hookworm Infection
Interventions: BIOLOGICAL: Na-ASP-2/Alhydrogel Hookworm Vaccine|BIOLOGICAL: Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Colonisation and Skin Quality Parameter Improvement by Probiotic Micrococcus Luteus Q24 Balm in Healthy Adults.
Status: RECRUITING
Conditions: Microbial Colonization
Interventions: OTHER: Micrococcus luteus Blis Q24 balm|OTHER: Placebo balm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: BI 655066 Dose Ranging in Psoriasis, Active Comparator Ustekinumab
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: BI 655066|DRUG: BI 655066|DRUG: Ustekinumab|DRUG: BI 655066
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Intima Media Thickness Regression in Dyslipidemic Teenagers
Status: COMPLETED
Conditions: Obesity|Dyslipidemia
Interventions: DRUG: Atorvastatin|DRUG: sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amiodarone Prophylaxis for Atrial Fibrillation in Patients Undergoing Surgery for Lung Cancer
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DRUG: Amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Precision Immuno-Oncology for Advanced Non-small Cell Lung Cancer Patients With PD-1 ICI Resistance (PIONeeR-BioMarkers (BM) Profiling)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer Patients
Interventions: PROCEDURE: BIOPSY|DIAGNOSTIC_TEST: blood-sampled|OTHER: feces samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Influence of Flap Position Following FibReORS
Status: COMPLETED
Conditions: Periodontitis|Periodontal Diseases
Interventions: PROCEDURE: FibReORS with apically positioned flap (apical position)|PROCEDURE: FibReORS with apically positioned flap (crestal position)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Prophylaxis in the Prevention of Surgical Site Infections After Selected Urgent Abdominal Surgical Procedures
Status: COMPLETED
Conditions: Acute Appendicitis|Perforated Gastroduodenal Ulcer|Small Bowel Obstruction
Interventions: DRUG: Metronidazole, Cefuroxime|DRUG: Amoxicillin (+ clavulanic acid) and Fluconazole|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Elliptical Training Versus Ergo-meter on Cardiopulmonary Parameters in Post CABG Patients
Status: COMPLETED
Conditions: Post-cardiac Surgery
Interventions: OTHER: Elliptical Training Group|OTHER: Ergo-metric Training Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Elder Mistreatment VOICES-CI Screening Tool
Status: COMPLETED
Conditions: Elder Abuse|Elder Mistreatment
Interventions: BEHAVIORAL: Virtual cOaching in making Informed Choices on Elder Mistreatment Self-Disclosure (VOICES)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Pilates Mat Versus Cervical Stabilization Exercises on Myoelectric Activity of Cervical Muscles in Forward Head Posture
Status: COMPLETED
Conditions: Musculoskeletal Diseases
Interventions: OTHER: Pilates mat exercises|OTHER: cervical stabilization exercises|OTHER: conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Colloidal Oatmeal, Colloid Cream, Diaper Rash, Preterm Neonates and Neonatal Intensive Care Unit
Status: COMPLETED
Conditions: Diaper Rash|Preterm Neonates
Interventions: BIOLOGICAL: Colloidal oatmeal|BIOLOGICAL: Cold cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-dose, Dose-escalation Study of a Long-acting MOD-6031 in Healthy Overweight or Obese Subjects
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: MOD-6031|OTHER: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Baxter: Actifuse SHAPE vs DBX in ACC
Status: UNKNOWN
Conditions: Cervical Spine Degenerative Disease Nos|Cervical Spondylosis With Myelopathy
Interventions: DEVICE: Actifuse SHAPE|DEVICE: Autograft with Demineralized Bone Matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Eye Movement Desensitization and Reprocessing Intervention in Hypertension Patient.
Status: COMPLETED
Conditions: Eye Movement Desensitization and Reprocessing Intervention|Blood Pressure|Heart Rate Variability|Anxiety
Interventions: BEHAVIORAL: Eye Movement Desensitization and Reprocessing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Proxinium for Treating Patients With Squamous Cell Head and Neck Cancer
Status: TERMINATED
Conditions: Squamous Cell Carcinoma of the Head and Neck|Carcinoma, Squamous Cell|Neoplasms, Squamous Cell|Head and Neck Neoplasms|Mouth Neoplasms|Head and Neck Cancer
Interventions: DRUG: Proxinium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Russian Current Parameters on MVIC Contraction of the Quadriceps Muscle Among University of Sharjah Students.
Status: UNKNOWN
Conditions: Quality of Life
Interventions: DEVICE: Russian Current
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I Prevention Study of Atorvastatin in Women at Increased Risk for Breast Cancer
Status: COMPLETED
Conditions: Atypical Ductal Breast Hyperplasia|Breast Cancer|Ductal Breast Carcinoma in Situ|Lobular Breast Carcinoma in Situ
Interventions: DRUG: atorvastatin calcium|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ALzheimer and MUsic THerapy: Effects of Music Lessons on Brain Plasticity, Mood, and Quality of Life in Alzheimer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease|Mild Cognitive Impairment|MCI With Increased Risk for Alzheimer Disease
Interventions: BEHAVIORAL: Music lessons|BEHAVIORAL: Training intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Walking Therapy for Neuropathic Pain Following Incomplete Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries|Neuropathic Pain
Interventions: OTHER: VR Game 1|OTHER: VR Game 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Botox Treatment on Chronical Scrotal Pain
Status: NOT_YET_RECRUITING
Conditions: Scrotum Disease|Chronic Pain
Interventions: DRUG: Botulinum toxin type A|OTHER: Sterile saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Researching the Effectiveness of Acceptance-Based Coping During Hospitalization
Status: COMPLETED
Conditions: Psychosis|Schizophrenia
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy (ACT)|BEHAVIORAL: Enhanced Treatment as Usual (eTAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Program of Dideoxycytidine ( ddC ) to Be Used in Combination With Zidovudine ( AZT ) for Treatment of Advanced HIV Disease
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Zalcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Vildagliptin Versus Sitagliptin in Patients With Type 2 Diabetes and Severe Renal Insufficiency (28-week Extension Study)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Renal Insufficiency
Interventions: DRUG: vildagliptin|DRUG: sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Brain Stimulation on Speech Fluency in Adults Who Stutter
Status: RECRUITING
Conditions: Stuttering, Adult
Interventions: DEVICE: rTMS (Repetitive TMS)|BEHAVIORAL: Speech training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Weight Inclusive and Adaptive Strategies to Enhance Cardiometabolic Health in Black Adults
Status: NOT_YET_RECRUITING
Conditions: Obesity|Prehypertension|Hypertension|PreDiabetes|Type 2 Diabetes|Dyslipidemia
Interventions: BEHAVIORAL: Weight-focused health coaching|BEHAVIORAL: Weight-neutral health coaching|BEHAVIORAL: Intensify lifestyle approach|OTHER: Augment with enhanced medical management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Chemoradiotherapy After Neoadjuvant Cisplatin and Docetaxel in the Nasopharynx Carcinoma
Status: COMPLETED
Conditions: Head and Neck Neoplasms
Interventions: DRUG: docetaxel and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GDC-0084 With Radiation Therapy for People With PIK3CA-Mutated Solid Tumor Brain Metastases or Leptomeningeal Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain Metastases|Leptomeningeal Metastasis
Interventions: DRUG: GDC-0084|RADIATION: whole brain radiation therapy radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pilates Exercises Applied With Face-to-Face and Telerehabilitation on Menstrual Pain
Status: RECRUITING
Conditions: Menstrual Pain
Interventions: OTHER: Pilates Exercises With Face-to-Face|OTHER: Pilates Exercises With Telerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Immunogenicity, and Protective Efficacy of Two Regimens of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites (PfSPZ Vaccine) During Natural Transmission Season in Healthy African Adults in Mali
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: PfSPZ Vaccine|DRUG: Normal Saline|DRUG: artemether 20mg/lumefantrine 120mg (AL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Standard Versus Extended Lymphadenectomy in Pancreatoduodenectomy for Patients With Pancreatic Head Adenocarcinoma
Status: UNKNOWN
Conditions: Carcinoma, Pancreatic Ductal
Interventions: PROCEDURE: Extended lymphadenectomy|PROCEDURE: Standard lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thyroid Hormones Homeostasis and Energy Metabolism Changes During Stimulation of Endogenously Secreted Bile Acids (BAs)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Sincalide|DRUG: Ursodiol|PROCEDURE: Fat Meal|PROCEDURE: Carb meal|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect of Optimized Behavioural Intervention Using The Multi-Phase Optimization Strategy (MOST).
Status: COMPLETED
Conditions: Dental Caries in Children|Early Childhood Caries
Interventions: BEHAVIORAL: Oral Health Behavioral Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigation The Effect of Conventional Vs. Individualized tDCS Intensity to Achieve Uniform E-Fields
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis|Neurophysiologic Abnormality
Interventions: DEVICE: Transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Phase 1 Trial of the TQB2928 Injection in Patients With Advanced Cancers
Status: UNKNOWN
Conditions: Advanced Solid Tumors and Hematological Malignancies
Interventions: DRUG: TQB2928 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Dose-Finding Study of TRC105 Plus Capecitabine for Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: TRC105|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing LY900014 to Insulin Lispro (Humalog) in Adults With Type 1 Diabetes Using Insulin Pump Therapy
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Ultra-Rapid Lispro|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of Caspofungin Versus Amphotericin B Deoxycholate in the Treatment of Invasive Candidiasis in Neonates and Infants (MK-0991-064)
Status: TERMINATED
Conditions: Candidiasis, Invasive
Interventions: DRUG: Caspofungin|DRUG: Amphotericin B Deoxycholate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intra-articular Hyaluronate Injection for Adhesive Capsulitis
Status: RECRUITING
Conditions: Adhesive Capsulitis
Interventions: PROCEDURE: Injection Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound and Near Infrared Imaging for Predicting and Monitoring Neoadjuvant Treatment
Status: COMPLETED
Conditions: Breast Cancer|Breast Tumors|Cancer of Breast|Cancer of the Breast|Malignant Neoplasm of Breast
Interventions: DEVICE: Optical Tomography Using Near Infrared Diffused Light Assisted with Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults
Status: RECRUITING
Conditions: Pediatric Solid Tumor|Germ Cell Tumor|Retinoblastoma|Hepatoblastoma|Wilms Tumor|Rhabdoid Tumor|Carcinoma|Osteosarcoma|Ewing Sarcoma|Rhabdomyosarcoma|Synovial Sarcoma|Clear Cell Sarcoma|Malignant Peripheral Nerve Sheath Tumors|Desmoplastic Small Round Cell Tumor|Soft Tissue Sarcoma|Neuroblastoma
Interventions: BIOLOGICAL: second generation 4-1BBζ EGFR806-EGFRt|BIOLOGICAL: second generation 4-1BBζ EGFR806-EGFRt and a second generation 4 1BBζ CD19-Her2tG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of Ceftobiprole in Neonates and Infants up to 3 Months Treated With Systemic Antibiotics
Status: TERMINATED
Conditions: Bacterial Infections
Interventions: DRUG: Ceftobiprole medocaril
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Consuming Enzymes and Prebiotics on Body Composition and Blood Biochemical Index
Status: COMPLETED
Conditions: Gut Microbiota
Interventions: OTHER: normal diet|OTHER: weight loss program kit|OTHER: weight loss program kit with A. muciniphila prebiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Women's Health Trial: Feasibility Study in Minority Populations
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Myocardial Ischemia|Postmenopause
Interventions: BEHAVIORAL: diet, fat-restricted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Z-Endoxifen Hydrochloride in Treating Patients With Metastatic or Locally Recurrent Estrogen Receptor-Positive Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2/Neu Positive|Recurrent Breast Carcinoma|Stage IIIC Breast Cancer AJCC v7|Stage IV Breast Cancer AJCC v6 and v7
Interventions: DRUG: Endoxifen Hydrochloride|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: cAMP Signaling and Muscle Adaptations
Status: UNKNOWN
Conditions: Muscle Hypertrophy in Healthy Young Men
Interventions: OTHER: No training|OTHER: Endurance training|OTHER: Resistance Training|DRUG: Terbutaline|DRUG: Clenbuterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Orexin s Role in the Neurobiology of Substance Use Disorder
Status: RECRUITING
Conditions: Nicotine Dependence
Interventions: DRUG: Belsomra|DRUG: Placebo|DRUG: Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Baby Nutrition and Physical Activity Self-Assessment for Child Care (NAP SACC) Intervention Study
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Baby NAP SACC|BEHAVIORAL: Back to Sleep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability and Pharmacokinetics Study Assessing Ascending Single Oral JTK-853 Doses in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JTK-853 or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Increasing Engagement and Improving HIV Outcomes Via HealthMPowerment
Status: COMPLETED
Conditions: HIV Infections|Sexually Transmitted Diseases|Stigma, Social
Interventions: BEHAVIORAL: Information Resources|BEHAVIORAL: Social Support|BEHAVIORAL: HIV Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Carboplatin Plus Gemcitabine for Elderly Patients With Stage IV NSCLC
Status: COMPLETED
Conditions: NSCLC
Interventions: DRUG: Carboplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stent Omission After Ureteroscopy and Lithotripsy in the Michigan Urological Surgery Improvement Collaborative
Status: RECRUITING
Conditions: Stone, Kidney|Stone Ureter
Interventions: DEVICE: Standard of care stent placement|OTHER: No stent placement|OTHER: Surveys
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Nighttime Postural Care: Caregiver Training Program and Outcome Measure Feasibility
Status: COMPLETED
Conditions: Knowledge, Attitudes, Practice
Interventions: OTHER: Sleep Care Positioning Training Program GRP1|OTHER: Sleep Care Positioning Training Program GRP2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Investigational Immuno-therapy Study of Nivolumab, Pomalidomide and Dexamethasone Combinations in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Elotuzumab|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Investigational Multi-Purpose Disinfecting Solution for Care of Soft Contact Lenses
Status: COMPLETED
Conditions: Contact Lens Care
Interventions: DEVICE: FID 107027 Multi-Purpose Disinfecting Solution|DEVICE: ReNu MultiPlus Multi-Purpose Solution No Rub Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Scaling Up Implementation Strategies to Improve the DIAGNOSE and PREVENT Pillars for Young MSM in Florida
Status: NOT_YET_RECRUITING
Conditions: Hiv
Interventions: BEHAVIORAL: Workforce Development: Tailored Motivational Interviewing and Technical Assistance|BEHAVIORAL: Quality Management, Mystery Shopper Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of COVID-19 DNA Vaccine (AG0302-COVID19)
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: AG0302-COVID19|BIOLOGICAL: AG0302-COVID19|BIOLOGICAL: AG0302-COVID19
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: First-line Chemotherapy With Temozolomide Alone for Non-enhancing Adult Brainstem Gliomas, With a Diffuse Subtype and Showing Clinical and/or Radiological Infiltrative Pattern of Progression
Status: UNKNOWN
Conditions: Adult Brainstem Glioma
Interventions: DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test How Different Doses of BI 456906 Are Tolerated in Japanese Men With a Body Mass Index (BMI) Between 23 and 40 kg/m2
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 456906|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Probiotic Blend to Reduce Gastrointestinal Symptoms in Patients With Irritable Bowel Syndrome
Status: RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Probiotic blend|DIETARY_SUPPLEMENT: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Empagliflozin (BI 10773) With Metformin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: BI 10773|DRUG: Glimepiride|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: MAPS Trial: Matrix And Platinum Science
Status: COMPLETED
Conditions: Intracranial Aneurysms
Interventions: DEVICE: Matrix 2® coils for endovascular aneurysm occlusion|DEVICE: GDC® coils for endovascular aneurysm occlusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chinese Medicine for Patients With LCOVID-19 Symptoms
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: COVID Rehab Formula granules|OTHER: Placebo granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concomitant Radiation and Cisplatin With and Without Tirapazamine in Treatment of Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Neoplasms
Interventions: DRUG: tirapazamine (SR259075)|DRUG: cisplatin|PROCEDURE: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamics and Pharmacokinetics of Dexmedetomidine in Pediatric
Status: UNKNOWN
Conditions: Pediatrics|Dexmedetomidine|Pharmacodynamics|Pharmacokinetics
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Family-Based Alcohol Preventive Intervention for Latino Emerging Adults
Status: COMPLETED
Conditions: Binge Alcohol Consumption|Risk Behavior, Health|Driving Under the Influence|High-Risk Sex|Identity, Social|Parenting
Interventions: BEHAVIORAL: Latino Emerging Adults (LEA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mechanism of Action of tACS for the Treatment of MDD
Status: COMPLETED
Conditions: Major Depressive Disorder|MDD
Interventions: DEVICE: tACS|DEVICE: Sham tACS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study About How ASP5354 Affects the Body in Healthy Adults and in Adults Whose Kidneys do Not Work Well
Status: COMPLETED
Conditions: Healthy Volunteers|Renal Impairment
Interventions: DRUG: pudexacianinium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Topical Sirolimus in Chemoprevention of Facial Squamous Cell Carcinomas in Solid Organ Transplant Recipients (SiroSkin)
Status: NOT_YET_RECRUITING
Conditions: Solid Organ Transplant Recipients|Skin Cancer
Interventions: DRUG: Sirolimus Topical Cream|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Using Whey Protein and Creatine Supplements on Muscular Strength in Weight-training Adult Males
Status: COMPLETED
Conditions: Nutritional Status
Interventions: DIETARY_SUPPLEMENT: Whey protein and creatine supplement|DIETARY_SUPPLEMENT: Whey protein only supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: "Red Morphine Drops" for Symptomatic Treatment of Dyspnoea in Lung Cancer
Status: COMPLETED
Conditions: Dyspnea|Lung Neoplasms
Interventions: DRUG: Morphine p.o.|DRUG: Morphine s.c.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AI-based Social Software to Manage wARfarin Therapy
Status: UNKNOWN
Conditions: Anticoagulant-induced Bleeding|Warfarin Sodium Causing Adverse Effects in Therapeutic Use
Interventions: BEHAVIORAL: AI-based social software management model|BEHAVIORAL: Human-based social software management model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Interest of Audiovisual Distraction in the Management of Anxiety and Pain During Oocyte Retrieval
Status: COMPLETED
Conditions: Fertilization in Vitro
Interventions: DEVICE: HappyMed Video Glasses|DRUG: Propofol|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Biomarkers for Predicting Macronutrient Intake
Status: RECRUITING
Conditions: Glucose Metabolism|Amino Acid Metabolism
Interventions: OTHER: Meal set A|OTHER: Meal set B|OTHER: Meal set C|OTHER: Meal set D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Efficacy and Safety of Edaravone Dexborneol Sequential Therapy in the Treatment of Patients With AIS
Status: NOT_YET_RECRUITING
Conditions: Subjects With Acute Ischemic Stroke
Interventions: DRUG: Edaravone Dexborneol Sequential Therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hs-Troponin T Kinetics in Patients Treated With MCO Membranes Compared to High-flux, Low-flux Membranes and HDF
Status: COMPLETED
Conditions: Troponin T
Interventions: DEVICE: Theranova 400|DEVICE: FX 10|DEVICE: FX CorDiax 800|DEVICE: HDF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Efficacy Trial of a Gravity Fed Household Water Treatment Device as a Delivery System for Zinc
Status: COMPLETED
Conditions: Diarrhoea
Interventions: DIETARY_SUPPLEMENT: Zinc enriched water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Effectiveness of Telemedicine in Identifying Diabetic Retinopathy Cases
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: OTHER: Tele-medicine|OTHER: Conventional referral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Fructose Supplementation in Carriers for Hereditary Fructose Intolerance
Status: COMPLETED
Conditions: Hereditary Fructose Intolerance
Interventions: OTHER: Experimental diet Fru rich diet|OTHER: Experimental low Fru diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Balance Reactions in a Virtual Environment With Avatar and/or Reinforced Visual Signal Compared to a Real Environment
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Intervention A : virtual environment with avatar|OTHER: Intervention B : virtual environment with reinforced visual signal|OTHER: Intervention C : virtual environment with avatar and reinforced visual signal|OTHER: Intervention D : real environment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Strengthening in Sub-acute Stroke Survivors: A Randomized Controlled Trial
Status: RECRUITING
Conditions: Hemiparesis;Poststroke/CVA
Interventions: PROCEDURE: Eccentric training|PROCEDURE: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ilaprazole for the Treatment of Duodenal Ulcer in Chinese Patients (Phase 2)
Status: COMPLETED
Conditions: Duodenal Ulcer
Interventions: DRUG: 5 mg ilaprazole|DRUG: 10 mg ilaprazole|DRUG: 20 mg ilaprazole|DRUG: 20 mg omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Laughter Yoga on Self-Care, Quality of Life and Stress Level in Menopause
Status: NOT_YET_RECRUITING
Conditions: Laughter|Menopause|Stress|Self
Interventions: BEHAVIORAL: Laughter Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The (Cost-)Effectiveness of Physician Assistants Working at the Primary Out of Hours Emergency Service
Status: COMPLETED
Conditions: Primary Healthcare|Out-of-hours Medical Care
Interventions: OTHER: Care provided by Physician Assistants
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Imatinib on Bone Metabolism in Patients With Chronic Myelogenous Leukemia or Gastrointestinal Stromal Tumors
Status: COMPLETED
Conditions: Gastric Cancer|Leukemia|Chronic Myelogenous Leukemia
Interventions: OTHER: blood test, urine test, and bone density x-ray.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Studying the Distribution of Accessory Gene Regulator (Agr) Quorum Sensing System and the Prevalence of Linezolid and Mupirocin Resistance in Biofilm Producer/Non Producer Staphylococcus Aureus in Sohag University Hospitals
Status: COMPLETED
Conditions: Staphylococcus Aureus
Interventions: DIAGNOSTIC_TEST: antibiotic sensitivity test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hydroxychloroquine Monotherapy and in Combination With Azithromycin in Patients With Moderate and Severe COVID-19 Disease
Status: COMPLETED
Conditions: Covid-19
Interventions: DRUG: HCQ|DRUG: HCQ+AZT|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of MVA Smallpox Vaccine in HIV-positive Subjects Who Are Vaccinia Naive
Status: TERMINATED
Conditions: HIV Infections|Smallpox
Interventions: BIOLOGICAL: MVA Smallpox Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Potential Biomarkers for Bevacizumab-Induced High Blood Pressure in Patients With Solid Tumor
Status: TERMINATED
Conditions: Breast Cancer|Cardiovascular Complications|Colorectal Cancer|Fallopian Tube Cancer|Head and Neck Cancer|Lung Cancer|Ovarian Cancer|Peritoneal Cavity Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: OTHER: laboratory biomarker analysis|OTHER: questionnaire administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antibiotic Treatment Trial for Small Intestinal Bacterial Overgrowth
Status: UNKNOWN
Conditions: Small Intestinal Bacterial Overgrowth
Interventions: DRUG: Metronidazole|DRUG: Ciprofloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Randomized Control Trial of Financial Incentives for Smoking Cessation
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: BEHAVIORAL: Individual Rewards|BEHAVIORAL: Fixed Deposits|BEHAVIORAL: Chosen Deposits|BEHAVIORAL: Competitive Deposits (Pari-Mutuel)|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Amount of Zinc to Include in a Lipid-based Nutrient Supplement (LNS)
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: LNS-Zn5|DIETARY_SUPPLEMENT: LNS-Zn10|DIETARY_SUPPLEMENT: LNS-Zn0|DIETARY_SUPPLEMENT: Suppl-Zn5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of Quinapril Hydrochloride 20 mg and Hydrochlorothiazide 25 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: fixed dose combination of Quinapril HCl 20 mg and Hydrochlorothiazide 25 mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Study Investigating the Role of Oxaliplatin Duration in Modified FOLFOX-6 or CAPOX Regimen as Adjuvant Colon Cancer Therapy
Status: UNKNOWN
Conditions: Colon Cancer
Interventions: DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Supplementation With a Fibre Enriched Paediatric Sip Feed For Children With Acute Lymphocytic Leukemia
Status: COMPLETED
Conditions: Acute Lymphocytic Leukemia
Interventions: DIETARY_SUPPLEMENT: NutriniDrink/Fortini MF unflavoured (1.5kcal/ml)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study for Safety and Tolerability of TOP1288 Administered Orally in Healthy Subjects
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: TOP1288|DRUG: Placebo to TOP1288
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of a Single Dose of Intravenous TD-8954 Compared With Metoclopramide in Critically Ill Patients With Enteral Feeding Intolerance
Status: COMPLETED
Conditions: Enteral Feeding Intolerance
Interventions: DRUG: TD-8954|DRUG: Metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT