pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy Study Of Tofacitinib In Pediatric JIA Population
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: CP-690,550 (tofacitinib)|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IIa Study of Redirected Autologous T Cells Engineered to Contain Anti-CD19 Attached to TCRz and 4-Signaling Domains in Patients With Chemotherapy Relapsed or Refractory CD19+ Lymphomas
Status: COMPLETED
Conditions: Non-Hodgkins Lymphoma (NHL) Patients, With CD19+B Cell Lymphomas
Interventions: BIOLOGICAL: CART-19
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NMES and Pelvic Fracture Rehabilitation
Status: COMPLETED
Conditions: Trauma|Rehabilitation
Interventions: DEVICE: Neuromuscular muscle stimulation machine- Strength Setting|DEVICE: Neuromuscular muscle stimulation machine - TENS Setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First In Human Study In Healthy People To Evaluate Safety, Toleration And Time Course Of Plasma Concentration Of Single Oral Doses Of PF-06273340
Status: COMPLETED
Conditions: PAIN
Interventions: DRUG: PF-06273340 or Placebo|DRUG: PF-06273340 or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The C-SPAN Coalition: Colorectal Cancer Screening and Patient Navigation
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Branch I|BEHAVIORAL: Branch II|BEHAVIORAL: Branch III|BEHAVIORAL: Branch IV|BEHAVIORAL: Branch V
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparative Study Between Vaginal Progesterone Alone or Combined With Aspirin in Prevention of Recurrent Preterm Birth
Status: COMPLETED
Conditions: Preterm Birth
Interventions: DRUG: Aspirin tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Usual Podiatric Care and Early Physical Therapy for Plantar Heel Pain
Status: COMPLETED
Conditions: Fasciitis, Plantar
Interventions: OTHER: Physical therapy after initial podiatry visit|OTHER: Usual care provided by podiatry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NOX-A12 Multiple Ascending Dose Study in Healthy Volunteers
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplantation
Interventions: DRUG: NOX-A12|DRUG: NOX-A12|DRUG: Filgrastim|DRUG: NOX-A12 in combination with Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monitoring Patients With Shortness of Breath With Repeated Ultrasound Examinations
Status: COMPLETED
Conditions: Dyspnea
Interventions: DEVICE: Focused ultrasound of the lungs (FLUS) and focused cardiac ultrasound (FoCUS)|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CSD1602: A Crossover Study to Evaluate the Exposure to "Tar" and Nicotine From Two King Size Menthol Cigarette Products
Status: COMPLETED
Conditions: Smoking
Interventions: OTHER: PD21864AA|OTHER: PD21864AB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Wavefront-guided PRK vs Wavefront-optimized PRK
Status: COMPLETED
Conditions: Myopia|Astigmatism
Interventions: PROCEDURE: Wavefront-guided PRK|PROCEDURE: Wavefront-optimized PRK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NAC in CC Resistant PCOS After LOD
Status: COMPLETED
Conditions: Clomiphene Citrate Resistant Polycystic Ovary Syndrome
Interventions: DRUG: N-acetyl-cysteine|DRUG: Clomiphene citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetics/Dynamics Ib Study of F-627 in Women With Breast Cancer Receiving Myelotoxic Chemotherapy
Status: COMPLETED
Conditions: Neutropenia
Interventions: BIOLOGICAL: F-627 240 μg/kg|BIOLOGICAL: F-627 320 μg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Etrumadenant and Zimberelimab in People With Dedifferentiated Liposarcoma
Status: RECRUITING
Conditions: Dedifferentiated Liposarcoma|Soft Tissue Sarcoma|Sarcoma,Soft Tissue|Sarcoma|Recurrent Dedifferentiated Liposarcoma|Unresectable Dedifferentiated Liposarcoma|Metastatic Dedifferentiated Liposarcoma
Interventions: DRUG: Etrumadenant|DRUG: Zimberelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Glycopyrronium or Indacaterol Maleate and Glycopyrronium Bromide Fixed-dose Combination Regarding Symptoms and Health Status in Patients With Moderate COPD Switching From Treatment With Any Standard COPD Regimen
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Glycopyrronium|DRUG: SABA|DRUG: LABA|DRUG: Indacaterol maleate and glycopyrronium bromide|DRUG: LAMA|DRUG: SAMA|DRUG: ICS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Individualized Therapy Trial for Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasm|Colorectal Cancer
Interventions: DRUG: Imatinib mesylate and panitumumab|DRUG: Standard-of-care treatment with panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of LCQ908 on Cardiovascular Risk
Status: TERMINATED
Conditions: Coronary Artery Disease|Hypertriglyceridemia
Interventions: DRUG: pradigastat (LCQ908)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Intravenous and Oral Moderate Sedation for First Trimester Surgical Abortions
Status: TERMINATED
Conditions: Undesired Intrauterine Pregnancy|First Trimester Pregnancy
Interventions: DRUG: Intravenous moderate sedation versus oral medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Different Toothpastes in Treating White Spot Lesions
Status: RECRUITING
Conditions: White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Interventions: OTHER: zinc carbonate nano-hydroxyapatite toothpaste|OTHER: 8% arginine toothpaste|OTHER: Fluoride toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose IL-2 Plus IFN-alpha Immunotherapy as Adjuvant Treatment of Renal Carcinoma.
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Interferon Alfa-2a|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Femoral Tunnel Position on Conventional MRI After Anterior Cruciate Ligament Reconstruction-Transtibial Technique Versus Transportal Technique
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Rupture
Interventions: PROCEDURE: transtibial technique|PROCEDURE: Transportal technique|PROCEDURE: anterior cruciate ligament reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Lung Ultrasounds and Transthoracic Electrical Bioimpedance in Preterm Infants With Respiratory Distress.
Status: UNKNOWN
Conditions: Respiratory Distress Syndrome in Premature Infant|Patent Ductus Arteriosus After Premature Birth|Perinatal Morbidity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pediatric Vasculitis Initiative
Status: RECRUITING
Conditions: Wegeners Granulomatosis (Granulomatosis With Polyangiitis)|Microscopic Polyangiitis|Eosinophilic Granulomatosis With Polyangiitis|Polyarteritis Nodosa|Takayasu Arteritis|Primary CNS Vasculitis|Unclassified Vasculitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Carboplatin, Cetuximab and RAD001 in Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Neoplasms|Cancer of the Head and Neck
Interventions: DRUG: Carboplatin|DRUG: Cetuximab|DRUG: RAD001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Find the Adequate Dose of Nalbuphine for Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Post Operative Pain|Opioid Side Effects
Interventions: DRUG: group A|DRUG: group B|DRUG: group C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Metabolism of Hydrocodone Bitartrate Controlled-Release (HC-CR) in Subjects With Hepatic Impairment
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: 20 mg HC-ER|DRUG: 20 mg HC-ER|DRUG: 20 mg HC-ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of rTMS in Patients With Spinal Cord Injury (rTMS:Repetetive Transcranial Magnetic Stimulation)
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DEVICE: repetitive transcranial magnetic stimulation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Pharmacokinetics of Anagrelide in Elderly and Young Patients With Essential Thrombocythaemia (ET)
Status: COMPLETED
Conditions: Essential Thrombocythaemia
Interventions: DRUG: anagrelide hydrochloride|DRUG: anagrelide hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard vs High-Dose Trivalent Inactivated Flu Vaccine in Adult Hematopoetic Stem Cell Transplant (HSCT) Recipients
Status: COMPLETED
Conditions: Adult Stem Cell Hematopoetic Transplant
Interventions: BIOLOGICAL: High-Dose Trivalent Inactivated Influenza Vaccine (HD-TIV)|BIOLOGICAL: Standard Dose Trivalent Inactivated Flu Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of 6 Week Reduced Exertion High Intensity Interval Training Protocol in Patients With Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Reduced-Exertion High-Intensity Interval Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess Treatment Satisfaction, Patient-reported Outcomes, Effectiveness, and Safety of a Fixed-dose Combination of Calcipotriene/Betamethasone Dipropionate PAD Cream in the Treatment of Mild-to-moderate Plaque Psoriasis of the Scalp in Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Plaque Psoriasis
Interventions: DRUG: CAL/BDP PAD Cream
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Safety and Efficacy of MK-1986 (Tedizolid Phosphate) and Comparator in Participants From Birth to Less Than 12 Years of Age With Acute Bacterial Skin and Skin Structure Infections (MK-1986-018)
Status: COMPLETED
Conditions: Acute Bacterial Skin and Skin Structure Infections
Interventions: DRUG: Tedizolid phosphate|DRUG: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Visceral Adiposity Index and Triglyceride/High-density Lipoprotein Cholesterol Ratio in the Congenital Hypogonadotropic Hypogonadism and Effect of Testosteron Treatment
Status: COMPLETED
Conditions: Hypogonadism
Interventions: DRUG: Testosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: ACTH in Progressive Forms of MS
Status: TERMINATED
Conditions: Secondary Progressive Multiple Sclerosis|Primary Progressive Multiple Sclerosis|Progressive Relapsing Multiple Sclerosis
Interventions: DRUG: ACTH|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcatheter Arterial Chemoembolization Therapy In Combination With Sorafenib
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Unresectable Hepatocellular Carcinoma|Carcinoma, Hepatocellular|Liver Neoplasm
Interventions: DRUG: TACE with sorafenib|PROCEDURE: TACE alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Normotonic Partial Nephrectomy as Novel Approach in Treating Small Renal Masses
Status: COMPLETED
Conditions: Renal Malignant Tumor|Renal Tumor
Interventions: PROCEDURE: Normotonic partial nephrectomy|PROCEDURE: Hypotonic partial nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurobiological Mechanisms of Chess as an Add-On Treatment Against SUD
Status: COMPLETED
Conditions: Substance Use Disorders
Interventions: BEHAVIORAL: Standard therapy for AUD plus Chess-based cognitive treatment|BEHAVIORAL: Standard therapy for AUD|BEHAVIORAL: Standard smoking cessation therapy for TUD plus Chess-based cognitive treatment|BEHAVIORAL: Standard therapy for TUD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utility of Cortical Bone Tissue Properties in the Assessment of Fracture Risk
Status: ACTIVE_NOT_RECRUITING
Conditions: Distal Radius Fracture|Osteoporosis|Hip Fractures
Interventions: DEVICE: Reference Point Indentation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bladder Catheters During Ablation Procedures
Status: COMPLETED
Conditions: Atrial Fibrillation|Catheter Ablation|Catheter Complications
Interventions: DEVICE: Insert bladder catheter|DEVICE: No catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Open-label Study of Levetiracetam Intravenous Infusion in Children (1 Month-4 Years Old) With Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of TAVR With SAVR in Younger Low Surgical Risk Patients With Severe Aortic Stenosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Valve Stenosis|Cardiovascular Diseases|Heart Diseases|Heart Valve Diseases|Ventricular Outflow Obstruction
Interventions: DEVICE: Transcatheter aortic valve replacement|DEVICE: Surgical aortic valve replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study Investigating the Extent of Paracetamol Absorption From a New Formulation of Paracetamol Compared With Panadol®
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Marketed paracetamol|DRUG: Experimental paracetamol formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Study of Sacituzumab Govitecan (SG) Versus Docetaxel in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: BIOLOGICAL: Sacituzumab Govitecan-hziy (SG)|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treosulfan-based Conditioning for Transplantation in AML/MDS
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: treosulfan|DRUG: Treosulfan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-Session Web-Based Training in Self-Compassion
Status: COMPLETED
Conditions: Stress|Anxiety|Depression
Interventions: BEHAVIORAL: Compassionate Care|BEHAVIORAL: Relaxing with Nature
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Nerve Block in Patients With Painful Diabetic Polyneuropathy
Status: RECRUITING
Conditions: Painful Diabetic Neuropathy|Neuropathic Pain|Neuropathy;Peripheral
Interventions: DIAGNOSTIC_TEST: Xylocaine 1%|DIAGNOSTIC_TEST: NaCl 9mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Cognitive Intervention and Rehabilitation Outcomes in Hip Fracture Patients
Status: RECRUITING
Conditions: Hip Fracture|Rehabilitation|Cognitive Intervention
Interventions: OTHER: specific cognitive intervention|OTHER: conventional occupational therapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Wrap Fixation Technique on the Results of Fundoplication
Status: COMPLETED
Conditions: Gastro Oesophageal Reflux Disease
Interventions: PROCEDURE: Nissen Fundoplication with wrap fixation|PROCEDURE: Nissen Fundoplication without wrap fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food Effect on Ceftibuten/VNRX-7145 in Healthy Participants
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: VNRX-7145|DRUG: Ceftibuten
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Counseling Hepatitis C Virus (HCV) Positive Patients for Cardiovascular Disease Risk Factors
Status: COMPLETED
Conditions: Hepatitis C|Atherosclerosis
Interventions: BEHAVIORAL: Patient counseling for HCV associated CVD risk factors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine, Carboplatin and Weekly Paclitaxel for Patients With Solid Tumors and Adenocarcinoma of Unknown Primary
Status: TERMINATED
Conditions: Tumors|Unknown Primary Tumors|Adenocarcinoma
Interventions: DRUG: Capecitabine|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Nipocalimab in Participants With Active Idiopathic Inflammatory Myopathies
Status: ACTIVE_NOT_RECRUITING
Conditions: Myositis
Interventions: DRUG: Nipocalimab|OTHER: Placebo|DRUG: Glucocorticoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Neuromuscular Relaxation in Patients for Thoraco-laparoscopic Esophagectomy
Status: COMPLETED
Conditions: Neuromuscular Block|Esophageal Cancer|Surgery
Interventions: DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: JetStream Atherectomy for the Treatment of In-stent Restenosis
Status: COMPLETED
Conditions: Femoropopliteal In-stent Restenosis
Interventions: DEVICE: JetStream XC with balloon angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Talazoparib in Determining Genetic Effects on Disease Response in Patients With Advanced Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Serous Adenocarcinoma|High Grade Ovarian Serous Adenocarcinoma|Ovarian Mass|Primary Peritoneal Serous Adenocarcinoma|Stage III Fallopian Tube Cancer AJCC v7|Stage III Ovarian Cancer AJCC v6 and v7|Stage III Primary Peritoneal Cancer AJCC v7|Stage IIIA Fallopian Tube Cancer AJCC v7|Stage IIIA Ovarian Cancer AJCC v6 and v7|Stage IIIA Primary Peritoneal Cancer AJCC v7|Stage IIIB Fallopian Tube Cancer AJCC v7|Stage IIIB Ovarian Cancer AJCC v6 and v7|Stage IIIB Primary Peritoneal Cancer AJCC v7|Stage IIIC Fallopian Tube Cancer AJCC v7|Stage IIIC Ovarian Cancer AJCC v6 and v7|Stage IIIC Primary Peritoneal Cancer AJCC v7|Stage IV Fallopian Tube Cancer AJCC v6 and v7|Stage IV Ovarian Cancer AJCC v6 and v7|Stage IV Primary Peritoneal Cancer AJCC v7
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: BMN 673
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SUCCESS (SelUtion, Safety, effiCaCy, hEalth economicS and promS) PTA Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Artery Disease
Interventions: DEVICE: SELUTION SLR™ (Sustained Limus Release) drug eluting balloon (DEB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adductor Canal Block (ACB) Versus ACB /Saphenous Block in Patients Undergoing Anterior Cruciate Ligament Repair
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: PROCEDURE: Ultrasound Guided Adductor Canal Block|PROCEDURE: Ultrasound Guided Saphenous Nerve Block|PROCEDURE: General anesthesia|DRUG: Bupivacaine 20 ml|DRUG: Bupivacaine 30ml|DRUG: Bupivacaine 10ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dasatinib and Cyclosporine in Treating Patients With Chronic Myelogenous Leukemia Refractory or Intolerant to Imatinib Mesylate
Status: TERMINATED
Conditions: Accelerated Phase Chronic Myelogenous Leukemia|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Chronic Phase Chronic Myelogenous Leukemia|Relapsing Chronic Myelogenous Leukemia
Interventions: DRUG: dasatinib|OTHER: diagnostic laboratory biomarker analysis|OTHER: pharmacological study|DRUG: cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cost-effectiveness of Four Methods in Preventing Fissure Caries in Permanent Teeth
Status: COMPLETED
Conditions: Dental Caries
Interventions: OTHER: ART dental sealant|OTHER: Resin dental sealant|OTHER: Sodium fluoride varnish|OTHER: Silver fluoride solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Nutritional Formula Supplementation on Growth of Prepubertal Children Treated With Stimulants Medications for Attention Deficit Hyperactivity Disorder (ADHD)
Status: RECRUITING
Conditions: ADHD - Attention Deficit Disorder With Hyperactivity
Interventions: DIETARY_SUPPLEMENT: Nutritional supplementation standardized formula.|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MOSAIC (MOthers' AdvocateS In the Community) for Pregnant Women and Mothers of Children Under 5 With Experience of Intimate Partner Violence (MOSAIC Plus) Open Trial
Status: NOT_YET_RECRUITING
Conditions: Intimate Partner Violence|Depression|Posttraumatic Stress Symptom
Interventions: BEHAVIORAL: MOSAIC Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Opioid Antagonism in Hypogonadotropic Hypogonadism
Status: ENROLLING_BY_INVITATION
Conditions: Hypogonadotropic Hypogonadism
Interventions: DRUG: Naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study in Healthy Volunteers
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: levodopa, carbidopa, ODM-104|DRUG: levodopa, carbidopa, entacapone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sunphenon EGCg (Epigallocatechin-Gallate) in the Early Stage of Alzheimer´s Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Epigallocatechin-Gallate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of Farnesyl Protein Transferase Inhibitor in Combination With Gemcitabine and Cisplatin in Advanced Cancer (Study P01499)(TERMINATED)
Status: TERMINATED
Conditions: Neoplasms
Interventions: DRUG: Farnesyl Protein Transferase Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy With Tacrolimus Resistant EBV CTL for Lymphoproliferative Disease After Solid Organ Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Post-transplant Lymphoproliferative Disease|Transplant-Related Hematologic Malignancy
Interventions: BIOLOGICAL: Autologous EBV-CTL transduced with vector SFG-CNA12|BIOLOGICAL: Autologous EBV-CTL transduced with control vector SFG-CNA8|PROCEDURE: Leucapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sensory Flicker and Electrical Flicker Stimulation
Status: COMPLETED
Conditions: Brain Diseases
Interventions: DEVICE: Customized version of DAVID device|DEVICE: Blackrock CereStim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Domperidone on the Nutrient Composition of Preterm Mother's Breast Milk
Status: COMPLETED
Conditions: Low Breast Milk Supply
Interventions: DRUG: Domperidone|DRUG: Placebo- Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Traction vs. No Traction in Colonic ESD
Status: RECRUITING
Conditions: Gastrointestinal Neoplasm
Interventions: PROCEDURE: Endoscopic Submucosal Dissection|DEVICE: Traction Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bioavailability Study of Risperidone Orally Disintegrating Tablets 1 mg of Dr.Reddy's Laboratories Limited Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Risperidone Orally Disintegrating Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Hypoxia in Persons With Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis|Multiple Sclerosis-Relapsing-Remitting|Multiple Sclerosis, Secondary Progressive
Interventions: OTHER: Acute Intermittent Hypoxia|OTHER: Sham-Acute Intermittent Hypoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gastropexy in the Repair of Patients With Paraesophageal Hernias
Status: RECRUITING
Conditions: Paraesophageal Hernia
Interventions: PROCEDURE: Gastropexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of T-allo10 in Hematopoietic Stem Cell Transplantation (HSCT) for Blood Disorders
Status: TERMINATED
Conditions: AML - Acute Myeloid Leukemia|MDS (Myelodysplastic Syndrome)|Mixed Phenotype Acute Leukemia|NHL - Non-Hodgkin's Lymphoma|Hodgkin's Lymphoma|ALL
Interventions: BIOLOGICAL: T-allo10
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Azacitidine in Transfusion Dependent Patients With Low-risk Myelodysplastic Syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMML)
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Chronic Myelomonocytic Leukemia
Interventions: DRUG: Azacitidine|DRUG: Erythropoetin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Fitting Guides in Alcon Multifocal Contact Lenses
Status: COMPLETED
Conditions: Presbyopia|Refractive Errors
Interventions: DEVICE: Lotrafilcon B multifocal contact lenses|DEVICE: Nelfilcon A multifocal contact lenses|DEVICE: Delefilcon A multifocal contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effects of Scapulothoracic Stabilization Exercises on Pain and Neck Function in Patients With Chronic Neck Pain
Status: RECRUITING
Conditions: Neck Pain
Interventions: PROCEDURE: Conventional Physical Therapy for Chronic Neck Pain|PROCEDURE: Scapulothoracic Stabilization Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block in Post-herpetic Neuralgia
Status: COMPLETED
Conditions: Postherpetic Neuralgia
Interventions: DRUG: Medical treatment|PROCEDURE: Real Erector Spinae block|PROCEDURE: Real Erector Spinae block with magnesium sulphate|PROCEDURE: Sham Erector Spinae block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Increased Access to Fruits and Vegetables for Hypertension in Immigrant Hispanic/Latinx Individuals
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Fruit and vegetable supplement|BEHAVIORAL: Dietary and chronic disease management education
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Method of Surgically Treating Varicose Veins and Venous Ulcers - a Study to Assess Clinical and Economic Value
Status: COMPLETED
Conditions: Varicose Veins|Venous Insufficiency|Venous Ulceration
Interventions: PROCEDURE: Surgery - Saphenofemoral ligation, saphenous strip and avulsions|PROCEDURE: EVLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency
Status: COMPLETED
Conditions: Metastatic Castration Resistant Prostate Cancer
Interventions: DRUG: Rucaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Multi-center, Open-label, Study of PR104 Versus PR104/Docetaxel in Non-Small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: PR104|DRUG: docetaxel|DRUG: docetaxel|DRUG: Granulocyte colony-stimulating factor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Innovative Drug Treatment Therapy for Pediatric Mitral Regurgitation
Status: RECRUITING
Conditions: Congenital Mitral Insufficiency
Interventions: DRUG: Captopril Tablets|DRUG: Metoprolol Oral Tablet|DRUG: Spironolactone Tablets|DRUG: Torsemide Tablets|DRUG: Potassium citrate powder
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics and Safety of Ravidasvir and Danoprevir/r in Healthy Volunteers China
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ravidasvir|DRUG: Danoprevir|DRUG: Ritonavir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ph I Safety and Efficacy of ODSH in Patients Receiving Induction or Consolidation Therapy for Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: ODSH
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of SRK-001 in Healthy Participants
Status: TERMINATED
Conditions: Healthy Participants
Interventions: DRUG: SRK-001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FibroScan ® Study: Assessing Liver Fibrosis in Patients Using Methotrexate for Psoriasis
Status: WITHDRAWN
Conditions: Psoriasis
Interventions: DIAGNOSTIC_TEST: Fibroscan and Fibrosure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Healthy Homes/Healthy Families (HH/HF) Intervention in 2-1-1 Callers
Status: COMPLETED
Conditions: Weight Change, Body
Interventions: BEHAVIORAL: Health Homes/Healthy Families (HH/HF) Intervention|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Intravenous Azithromycin to Eradicate Ureaplasma Respiratory Tract Infection in Preterm Infants
Status: COMPLETED
Conditions: Ureaplasma Infections
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Computerized Questionnaires in Assessing Symptoms, Pain, Depression, and Physical Function in Patients With Metastatic and/or Advanced Locoregional Cancer
Status: COMPLETED
Conditions: Cachexia|Depression|Pain|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: OTHER: computer-assisted intervention|OTHER: questionnaire administration|PROCEDURE: assessment of therapy complications|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility, Acceptability and Preliminary Treatment Effects of A-CRA for Youth in Compulsory Institutional Care
Status: RECRUITING
Conditions: Substance Use Disorders|Criminal Behavior
Interventions: BEHAVIORAL: A-CRA|BEHAVIORAL: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A HR20031 FE Study on Healthy Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: HR20031 FDC|DRUG: HR20031 FDC|DRUG: HR20031 FDC|DRUG: HR20031 FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pathogenesis of Non-alcoholic Steatohepatitis and Liver Regeneration After Bariatric Surgery
Status: UNKNOWN
Conditions: Bariatric Surgery Candidate|Nonalcoholic Steatohepatitis|Obesity
Interventions: PROCEDURE: Sleeve-Gastrectomy, Roux en Y gastric bypass
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Does Sugared or Sugar Free Chewing Gum Reduces Postoperative Ileus After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Postoperative Ileus.
Interventions: OTHER: sugar free chewing gum|OTHER: sugared chewing gum|DRUG: Tab. Midazolam 7.5 mg|DRUG: Inj. Midazolam 0.7mg/kg 45 min before surgery|DRUG: Inj. Propofol 2.5mg/kg|DRUG: Inj. Atracurium 0.5 mg/kg|DRUG: Sevoflurane 2.5 vol %|DRUG: Inj. Cefuroxime 1.5 g IV|DRUG: Inj. Ketorolac 30 mg IV|DRUG: Inj. Zantac 50mg IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: WATCH-TAVR, WATCHMAN for Patients With Atrial Fibrillation Undergoing Transcatheter Aortic Valve Replacement
Status: COMPLETED
Conditions: Atrial Fibrillation|Aortic Valve Stenosis
Interventions: DEVICE: WATCHMAN|DEVICE: TAVR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Two Concurrent Injections of AA4500 in Adult Subjects With Multiple Dupuytren's Contractures
Status: COMPLETED
Conditions: Dupuytren's Contracture
Interventions: BIOLOGICAL: XIAFLEX / XIAPEX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coronary Flow Reserve to Assess Cardiovascular Inflammation (CIRT-CFR)
Status: COMPLETED
Conditions: Coronary Heart Disease|Metabolic Syndrome|Diabetes Mellitus
Interventions: RADIATION: PET scan|RADIATION: Echocardiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of the Safety of MDX-1342 in Combination With Methotrexate in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: MDX-1342
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enteric-coated Mycophenolate Sodium (EC-MPS) With Reduced-dose Tacrolimus Versus EC-MPS With Standard-dose Tacrolimus in Stable Kidney Transplant Recipients
Status: COMPLETED
Conditions: Kidney Diseases
Interventions: DRUG: Enteric-coated mycophenolate sodium (EC-MPS)|DRUG: Tacrolimus|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Lactulose in Children With Chronic Liver Disease
Status: TERMINATED
Conditions: Minimal Hepatic Encephalopathy
Interventions: DRUG: Lactulose|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Manual Acupuncture for Primary Dysmenorrhea
Status: UNKNOWN
Conditions: Primary Dysmenorrhea
Interventions: DEVICE: Verum acupuncture|DEVICE: Sham acupuncture|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Urinary Catheter Self-Discontinuation After Urogynecology Surgery
Status: RECRUITING
Conditions: Urinary Retention|Pelvic Organ Prolapse|Stress Urinary Incontinence|Catheter Related Complication
Interventions: PROCEDURE: Catheter self-discontinuation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liver Cancer Disparities in American Indian and Alaska Native Persons
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Cirrhosis, Liver|Hepatitis B
Interventions: DIAGNOSTIC_TEST: Ultrasound or abbreviated MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Trial of Pelvic Floor Chemodenervation in Patients Undergoing Physical Therapy for High Tone Pelvic Floor Dysfunction
Status: COMPLETED
Conditions: Pelvic Pain|Dyspareunia|Pelvic Floor Dysfunction
Interventions: DRUG: Botulinum toxin A 50u|DRUG: Botulinum toxin A 100u|DRUG: Botulinum toxin A 150u
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Wireless Monitoring in Internal Medicine Unit for Ongoing Assessment of Acute Instable Patients
Status: UNKNOWN
Conditions: Wireless Vital Signs Monitoring System|Acutely Ill Complex and Poly-pathological Patients|Internal Medicine Unit Mission
Interventions: DEVICE: WIN @ Hospital system|OTHER: Traditional monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oblimersen Plus Doxorubicin and Docetaxel in Treating Patients With Metastatic or Locally Advanced Breast Cancer
Status: TERMINATED
Conditions: Male Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer
Interventions: BIOLOGICAL: oblimersen sodium|DRUG: doxorubicin hydrochloride|DRUG: docetaxel|BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim|PROCEDURE: therapeutic conventional surgery|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integration of Cognitive Processing Therapy and Relapse Prevention for Alcohol Use Disorder and PTSD
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder|Alcohol Use Disorder
Interventions: BEHAVIORAL: Cognitive Processing Therapy + Relapse Prevention|BEHAVIORAL: Relapse Prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Gefapixant (MK-7264) in Adult Participants With Chronic Cough (MK-7264-027)
Status: COMPLETED
Conditions: Chronic Cough
Interventions: DRUG: Placebo|DRUG: Gefapixant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Edoxaban vs. Warfarin in Subjects Undergoing Cardioversion of Nonvalvular Atrial Fibrillation (NVAF)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Edoxaban|DRUG: Warfarin|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Prediction Model of NAC Response for Breast Cancer Based on The Parametric Dynamics Features.
Status: COMPLETED
Conditions: Breast Cancer|Chemotherapy Effect|Diffusion Weighted MRI|PET Imaging|Multiparametric Magnetic Resonance Imaging
Interventions: RADIATION: Whole body 18F-FDG Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Long-term Treatment Study of MRA for Rheumatoid Arthritis (RA) From Study MRA213JP
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: MRA (Tocilizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Find the Best Dose of BI 1387446 Alone or in Combination With Ezabenlimab (BI 754091) in Patients With Different Types of Advanced or Metastatic Cancer (Solid Tumors)
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: BI 1387446|DRUG: BI 754091
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beta Blocker Therapy in Mild to Moderate Asthmatics
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Propranolol|DRUG: Placebo|DRUG: Qvar 50|DRUG: Qvar 100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy ofJaktinib Hydrochloride Tablets in Severe Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: Jaktinib Hydrochloride Tablets|DRUG: Jaktinib Hydrochloride Tablets|DRUG: Jaktinib Hydrochloride Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cocoa Supplementation Peripheral and Autonomic Diabetic Neuropathy
Status: RECRUITING
Conditions: Diabetic Neuropathies
Interventions: DIETARY_SUPPLEMENT: Cocoa|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Reproducibility Of Diffusion Weighted Magnetic Resonance Imaging For Neuroendocrine Tumor Liver Metastases
Status: COMPLETED
Conditions: Gastro-enteropancreatic Neuroendocrine Tumor|Secondary Malignant Neoplasm of Liver
Interventions: OTHER: magnetic resonance imaging (MRI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p