pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Mindfulness-Based Intervention for Depression and Insulin Resistance in Adolescents
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes|Depression|Insulin Resistance|Obesity|Adolescent Development
Interventions: BEHAVIORAL: Mindfulness-Based Intervention|BEHAVIORAL: Cognitive-Behavioral Therapy|BEHAVIORAL: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bilateral Superficial Cervical Plexus Block in Thyroid/Parathyroid Surgery
Status: UNKNOWN
Conditions: Benign Tumor of Thyroid|Hyperparathyroidism
Interventions: PROCEDURE: Bilateral superficial cervical plexus block with 0.25% bupivacaine 8 ml each (total 16 ml)|DRUG: Dexmedetomidine plus propofol infusion|PROCEDURE: Local infiltraion analgesia|PROCEDURE: General anesthesia with endotracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retrograde Light Target Tracheal Intubation Technique:Clinical Comparison With Direct Pharyngoscopic Tracheal Intubation
Status: COMPLETED
Conditions: Tracheal Intubation Morbidity
Interventions: PROCEDURE: light guided tracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Metabolic Effects of Antipsychotics in Children
Status: COMPLETED
Conditions: Aggression|Attention Deficit-Hyperactivity|Oppositional Defiant Disorder|Pervasive Development Disorders|Bipolar Disorder
Interventions: DRUG: risperidone|DRUG: olanzapine|DRUG: aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of AG-348 in Regularly Transfused Adult Participants With Pyruvate Kinase Deficiency (PKD)
Status: COMPLETED
Conditions: Pyruvate Kinase Deficiency|Anemia, Hemolytic
Interventions: DRUG: AG-348
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Effects of Famotidine Pretreatment and of Food on the Relative Bioavailability of BMS-986165 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986165|DRUG: Famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction Study of Tivantinib (ARQ 197) With Omeprazole, S-warfarin, Caffeine, Midazolam, and Digoxin in Cancer Subjects
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: tivantinib|DRUG: omeprazole|DRUG: s-warfarin|DRUG: caffeine|DIETARY_SUPPLEMENT: vitamin K|DRUG: digoxin|DRUG: midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Clinical Results of Derotational Osteotomy Based on 3D Osteotomy Template for Treatment of Recurrent Patellar Dislocation Combined With Patellofemoral Maltracking
Status: UNKNOWN
Conditions: Recurrent Patellar Dislocation|Osteotomy|Patellar Maltracking
Interventions: PROCEDURE: computer-assisted surgery|PROCEDURE: traditional osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Screening of Obstructive Sleep Apnea Syndrome in Residents of a Unit of Long-term Care Under Mixed Food
Status: TERMINATED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DEVICE: RU sleeping®|OTHER: autonomy scale (ADL and AGGIR)|OTHER: various activity scale (IADL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Relationship Between Red Cell Distribution Width (RDW) and HbA1C in Patients With Type 2 Diabetes Mellitus After Glycemic Control
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DIAGNOSTIC_TEST: Glycated hemoglobin (HbA1C)|DIAGNOSTIC_TEST: RDW|DIAGNOSTIC_TEST: Lipid profile
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Zinc, Iron, Vitamin A and Psychosocial Care for Child Growth and Development
Status: COMPLETED
Conditions: Development|Iron Deficiency|Zinc Deficiency
Interventions: DIETARY_SUPPLEMENT: Zinc Alone|DIETARY_SUPPLEMENT: Iron and Zinc|DIETARY_SUPPLEMENT: Iron, Zinc and Vitamin A|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Monoclonal Antibody Plus Chemotherapy in Treating Young Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: asparaginase|DRUG: cytarabine|DRUG: gemtuzumab ozogamicin|DRUG: mitoxantrone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Unsupervised Inspiratory Muscle Training on Ventilation Variability in Post-covid-19 Patients.
Status: RECRUITING
Conditions: COVID-19
Interventions: DEVICE: Experimental Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Could Wearing Face Mask Have Affected Demodex Parasite
Status: COMPLETED
Conditions: Pandemic, COVID-19|Demodex Infestation
Interventions: DIAGNOSTIC_TEST: standard superficial skin biopsy (SSSB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study of SHR2554 With Chemotherapy in Treatment-naïve Patients With Peripheral T-cell Lymphoma
Status: RECRUITING
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: SHR2554/CHOP|DRUG: SHR2554/CHOEP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Exercises on Computer Vision Syndrome
Status: UNKNOWN
Conditions: Neck Pain|Dry Eye Syndromes|Head Pain|Eye Strain|Asthenopia|Computer Vision Syndrome
Interventions: OTHER: figure eight vision exercise|OTHER: chin nodding|OTHER: neck stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Food Effect of TNP-2198 Capsules After Single Oral Dose in Healthy Participants
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: TNP-2198|DRUG: TNP-2198 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Research on the Application of Blood Collection Through Midline Catheters of Different Lengths
Status: NOT_YET_RECRUITING
Conditions: Catheter Complications
Interventions: BEHAVIORAL: Long peripheral venous catheters for blood collection|BEHAVIORAL: Midline catheter for blood collection|BEHAVIORAL: SPCs for blood collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: [18F]FLOR (FC303) PET/CT Imaging in Patients With Prostate Cancer
Status: TERMINATED
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: [18F]FLOR (FC303) Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of L-lysine on Human Gastrointestinal Secretion: A Dose-finding Study Applying Magnetic Resonance Imaging (MRI)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: L-lysine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial to Evaluate the Safety and Immunogenicity of Mumps Vaccine
Status: COMPLETED
Conditions: Mumps
Interventions: BIOLOGICAL: Mumps vaccine|BIOLOGICAL: measles, mumps and rubella combined vaccine, live
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Impact of 3 Methods of Communication on the Adherence of Methotrexate in Patients With Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Methotrexate|Polyarthritis; Rheumatoid
Interventions: OTHER: Communication methods to encourage adherence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Assess the Efficacy and Safety of Intravitreal Ranibizumab in People With Vision Loss Due to Macular Edema
Status: COMPLETED
Conditions: Macular Edema (ME)
Interventions: OTHER: Sham control|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Asacol Acute Diverticulitis(DIVA)Study
Status: COMPLETED
Conditions: Diverticulitis
Interventions: DRUG: Mesalamine|DRUG: Probiotic|DRUG: Placebo|OTHER: Dietary Advice|DRUG: Antibiotic for Diverticulitis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Dynamic Navigation System on Zygomatic Implant Placement
Status: RECRUITING
Conditions: Dental Implants|Surgery, Computer-Assisted
Interventions: DEVICE: Freehand zygomatic implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anxiety Reduction During Office Procedural Medicine Using Aromatherapy
Status: COMPLETED
Conditions: Anxiety|Anxiety State|Procedural Anxiety
Interventions: OTHER: Lavender Aromatherapy|OTHER: Placebo Aromatherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Continuous Jugular Venous Oxygen Saturation (SjO2) Measurement After Cardiac Arrest
Status: NOT_YET_RECRUITING
Conditions: Cardiac Arrest
Interventions: DEVICE: Continuous SjO2 monitoring with a TriOx PICC catheter|DIAGNOSTIC_TEST: Intermittent SjO2 monitoring with a TriOx PICC catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rifaximin Associated With Classic Triple Therapy for the Eradication of Helicobacter Pylori Infection
Status: COMPLETED
Conditions: Bacterial Infection Due to Helicobacter Pylori (H. Pylori)
Interventions: DRUG: Rifaximin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Medicaid Policy Interventions on Racial Equity in Severe Maternal Morbidity
Status: RECRUITING
Conditions: Severe Maternal Morbidity|Maternal Death
Interventions: BEHAVIORAL: Medicaid healthcare quality interventions (equity payment and obstetric bundled payment)|BEHAVIORAL: Doula|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Oxycodone/Naloxone (OXN) Combination in Moderate to Severe Non-malignant Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Oxycodone and naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Inflammation Around Implants With a Laser or an Ultrasonic Device
Status: COMPLETED
Conditions: Peri-implant Mucositis
Interventions: RADIATION: Er:Yag laser|DEVICE: EMS ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Bacillus Clausii Administration on Irritable Bowel Syndrome Patients
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Bacillus clausii|DRUG: Trimebutine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Subcutaneous Nivolumab + Relatlimab Fixed-dose Combination (FDC) in Previously Untreated Metastatic or Unresectable Melanoma
Status: RECRUITING
Conditions: Melanoma
Interventions: DRUG: Nivolumab + Relatlimab|DRUG: rHuPH20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Plaque and Anti-Gingivitis Effects of Moringa Plant Extract and Fluoride Toothpastes
Status: UNKNOWN
Conditions: Oral Disease
Interventions: DRUG: Moringa oleifera leaf
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Immunogenicity and Pharmacokinetics of ONC-841
Status: WITHDRAWN
Conditions: Advanced Solid Tumor
Interventions: DRUG: ONC-841|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study of MGTA-117 in Patients With Adult Acute Myeloid Leukemia (AML) and Myelodysplasia-Excess Blasts (MDS-EB)
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Myelodysplasia
Interventions: BIOLOGICAL: MGTA-117
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ivabradine in Patients With Congestive Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DRUG: Ivabradine Oral Tablet|DRUG: Blacebo plus standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Buffering Capacity of Matcha Green Tea on Salivary PH After an Acidic Attack
Status: NOT_YET_RECRUITING
Conditions: Diet Habit
Interventions: OTHER: Hot Matcha brew|OTHER: Water|OTHER: Cold matcha brew
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Bioequivalence Study of Docetaxel Injection in Patients With Solid Tumours
Status: COMPLETED
Conditions: Docetaxel|Solid Tumours|Bioequivalence
Interventions: DRUG: BH009 (Docetaxel injection)|DRUG: Docetaxel injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: NeoPatch Used as Adjunct in Foot and Ankle Tendon Surgery
Status: COMPLETED
Conditions: Tendinopathy|Tendon Tear|Tendon Injuries|Foot Ankle Injuries
Interventions: OTHER: NeoPatch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Efficacy and Safety Study of R935788 in the Treatment of Persistent/Chronic Immune Thrombocytopenic Purpura (ITP)
Status: COMPLETED
Conditions: Immune Thrombocytopenic Purpura
Interventions: DRUG: Fostamatinib disodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Body Contouring: Abdominoplasty and Liposuction
Status: COMPLETED
Conditions: Subcutaneous Abdominal Fat|Abdominal Skin Elasticity|Rectus Muscle Diastasis|Unpleasant Body Contour
Interventions: PROCEDURE: Abdominoplasty and liposuction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Phase I Study Evaluating the Addition of Bortezomib to an Established Acute Graft Versus Host Disease Prophylaxis Regimen in Pediatric Allogeneic Hematopoietic Stem Cell Transplant Patients
Status: COMPLETED
Conditions: Hematopoetic Stem Cell Transplant
Interventions: DRUG: Bortezomib administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 2b, Safety and Efficacy Study of Boceprevir in Patients Coinfected With HIV and Hepatitis C (P05411 AM4)
Status: COMPLETED
Conditions: HIV Infections|Hepatitis C|HCV Infection
Interventions: DRUG: PegIFN-2b|DRUG: RBV|DRUG: Placebo to Boceprevir|DRUG: Boceprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Superior Efficacy of Cardiac Resynchronization (SyncAVTM) Using the SyncAVTM Algorithm
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Abbott Medical® CRT device with SyncAVTM stimulation function|DEVICE: Abbott Medical® CRT device with biventricular stimulation (BiV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: QUantitative Assessment of Swallowing After Radiation (QUASAR)
Status: RECRUITING
Conditions: Head and Neck Cancer|Dysphagia|Oropharyngeal Dysphagia|Oropharynx Cancer|Oropharynx Squamous Cell Carcinoma
Interventions: RADIATION: Radiation Therapy|DRUG: Cetuximab|DRUG: Chemotherapy|DRUG: Immunotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bicalutamide to Block TMPRSS2 in Males With COVID-19 Infection
Status: WITHDRAWN
Conditions: COVID-19
Interventions: DRUG: Bicalutamide 150 Mg Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Etonogestrel Implants Protect Ovarian Reserve Function in Systemic Lupus Erythematosus
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Etonogestrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Obinutuzumab, Zanubrutinib, and Lenalidomide Followed Short-Cycle of Obinutuzumab and Cytarabine in Newly Diagnosed Mantle Cell Lymphoma
Status: RECRUITING
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Obinutuzumab|DRUG: Zanubrutinib|DRUG: Lenalidomide|DRUG: Cytarabine|BIOLOGICAL: CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aprepitant for the Prevention of Chemotherapy-induced Nausea and Vomiting
Status: UNKNOWN
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Aprepitant+palonosetron+dexamethasone|DRUG: palonosetron+dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Time Efficiency Comparison of Two IntraVitreal Injection Techniques
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration|Diabetic Macular Edema|Retinal Vein Occlusion With Macular Edema|Uveitic Macular Edema|Choroidal Neovascularization
Interventions: DEVICE: Intravitreal injection guide (Malosa)|DEVICE: Dual Blade Eyelid Speculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Risk of CMV Infection of the Renal Transplant About R + by Cellular Immunity Analyzed by the QuantiFERON ®-CMV Test.
Status: TERMINATED
Conditions: Renal Transplant Recipient|Immunized Against the Cytomegalovirus
Interventions: BIOLOGICAL: CMV Infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial of AVL-3288 in Schizophrenia Patients
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: AVL-3288|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pedometer Activity Monitoring After ASCT
Status: COMPLETED
Conditions: Lymphoma|Myeloma|High-dose Chemotherapy|Autologous Stem Cell Transplantation
Interventions: BEHAVIORAL: Pedometer-based activity monitoring after ASCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 3b Safety and Efficacy Study of Apremilast to Treat Moderate to Severe Plaque-plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis|Psoriatic Arthritis
Interventions: DRUG: Apremilast|DRUG: Etanercept|DRUG: Placebo tablet|DRUG: Placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Stress Response in Bariatric Surgery With and Without the Use of Opioids
Status: RECRUITING
Conditions: Opioid Use, Unspecified|Bariatric Surgery Candidate
Interventions: DRUG: Opioid Free Anaesthesia|DRUG: Opioid based anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Neoadjuvant Chemotherapy on Survival Outcomes in Patients With Variant Histologies Bladder Cancer Who Underwent Radical Cystectomy
Status: COMPLETED
Conditions: Bladder Cancer|Bladder Cancer Stage I|Bladder Cancer Stage II
Interventions: DRUG: Cisplatin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Instrument Assisted Soft Tissue Mobilization and Kinesiology Taping on Plantar Fasciitis
Status: COMPLETED
Conditions: Plantar Fascitis
Interventions: DEVICE: Instrument assisted soft tissue mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Individualized Studies of Triggers of Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation Paroxysmal
Interventions: BEHAVIORAL: N-of-1|BEHAVIORAL: Data Tracking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravitreal Ranibizumab on Radiation Retinopathy Following Plaque Brachytherapy for Choroidal Melanoma
Status: COMPLETED
Conditions: Radiation Retinopathy|Choroidal Melanoma
Interventions: DRUG: Ranibizumab|DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vestibular Stimulation and Neurodevelopmental Technique on Hypotonic Cerebral Palsy While Controlling the Gender
Status: COMPLETED
Conditions: Cerebral Palsy|Hypotonia
Interventions: OTHER: Vestibular stimulation|OTHER: Neck Control facilitation exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of MK-1248 With and Without Pembrolizumab (MK-3475) for Participants With Advanced Solid Tumors (MK-1248-001)
Status: TERMINATED
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: MK-1248|BIOLOGICAL: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Aortic Valve 18F System for the Treatment of Patients With Severe Aortic Stenosis
Status: UNKNOWN
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: Replacement of the Aortic Stenotic Valve
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intramuscular Oxytocin on Sensory Function in Healthy Volunteers With Ultraviolet Burn Injury to the Skin
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: Oxytocin|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Everolimus and Combination Chemotherapy in Treating Patients With Metastatic Stomach or Esophageal Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Esophagus|Adenocarcinoma of the Gastroesophageal Junction|Diffuse Adenocarcinoma of the Stomach|Intestinal Adenocarcinoma of the Stomach|Mixed Adenocarcinoma of the Stomach|Recurrent Esophageal Cancer|Recurrent Gastric Cancer|Stage IV Esophageal Cancer|Stage IV Gastric Cancer
Interventions: DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin|DRUG: everolimus|OTHER: laboratory biomarker analysis|OTHER: immunohistochemistry staining method|GENETIC: microarray analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Cryoenergy to Faciltate Myectomy in Hypertrophic Obstructive Cardiomyopathy: Comparison With the Classical Approach
Status: COMPLETED
Conditions: Septal Hypertrophy|Obstructive Hypertrophic Cardiomyopathy
Interventions: PROCEDURE: Cryo myectomy|PROCEDURE: Myectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of tDCS on Reducing Craving in Patients Practicing Chemsex: a Single-center, Double-blind, Randomized Controlled Pilot Trial
Status: RECRUITING
Conditions: Chemsex
Interventions: DEVICE: tDCS|BEHAVIORAL: Assessment of risk behaviours|OTHER: Scales
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Immunogenicity of Zostavax® in Patients With Antibody Deficiency 60 Years of Age and Older
Status: TERMINATED
Conditions: Common Variable Immune Deficiency|Specific Antibody Deficiency|X-linked Agammaglobulinemia
Interventions: BIOLOGICAL: Zostavax®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mindfulness-based Psychoeducation and Defense Mechanisms, Mindful Awareness
Status: COMPLETED
Conditions: Mindfulness|Psychoeducation|Defense Mechanisms|Awareness
Interventions: BEHAVIORAL: mindfulness-based psychoeducation program|BEHAVIORAL: ongoing life
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluate the PK Efficacy Safety and Tolerability of Pegcetacoplan in Patients With Thrombotic Microangiopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Transplant-Associated Thrombotic Microangiopathy
Interventions: DRUG: Pegcetacoplan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evidence Based Best Care Practice for Benign Paroxysmal Positional Vertigo
Status: COMPLETED
Conditions: Benign Paroxysmal Positional Vertigo
Interventions: BEHAVIORAL: DIZZTINCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy Study of EVO101 Topical Cream in Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis Eczema
Interventions: DRUG: EVO101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Functional Electrical Stimulation
Status: COMPLETED
Conditions: Rupture of Anterior Cruciate Ligament
Interventions: DEVICE: Functional electrical stimulation|DEVICE: Neuro-muscular electrical stimulation|PROCEDURE: Active exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Association of Photobiomodulation With Platelet Rich Plasma Intradermal Injection for Facial Rejuvenation
Status: UNKNOWN
Conditions: Wrinkle
Interventions: PROCEDURE: PRP application|OTHER: Placebo PRP application|RADIATION: Photobiomodulation|OTHER: Placebo Photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Gamma Transcranial Alternating Current Stimulation to Reduce Beta-amyloid Load and Improve Memory
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: Transcranial alternating current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A PK-PD Study of PSN821 in Type 2 Diabetes Patients (T2DM)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: PSN821|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physiotherapy in Post COVID-19 Syndrome Patients
Status: COMPLETED
Conditions: Post-COVID-19 Syndrome
Interventions: OTHER: Cognitive behavioral principles-based treatment program|OTHER: Control intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Performance and Safety of T2769 Versus Hylo-Forte® in the Treatment of Moderate to Severe Dry Eye Syndrome.
Status: NOT_YET_RECRUITING
Conditions: Dry Eye Syndrome
Interventions: DEVICE: T2769|DEVICE: Hylo-Forte®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Physical Activity Promotion on Short and Long-term Outcomes in COPD
Status: COMPLETED
Conditions: COPD|Emphysema|Chronic Bronchitis
Interventions: BEHAVIORAL: Pedometer and Website
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetes Nutrition Algorithms - Sugars: Galactose- and Fiber-induced Metabolic Improvement in the Dietetic Treatment of Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Dietary supplement (4 arms, 2 active, 2 placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vudalimab for the Treatment of Locally Advanced or Metastatic Anaplastic Thyroid Cancer or Hurthle Cell Thyroid Cancer
Status: UNKNOWN
Conditions: Locally Advanced Thyroid Gland Anaplastic Carcinoma|Metastatic Thyroid Gland Anaplastic Carcinoma|Metastatic Thyroid Gland Oncocytic Carcinoma
Interventions: DRUG: Vudalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Consumption of a Fermented Milk on Common Infections in Shift-workers
Status: COMPLETED
Conditions: Infectious Diseases|Healthy Subjects|Respiratory Tract Infections|Sore Throat|Sinusitis|Otitis|Bronchitis|Pneumonia|Influenza|Gastroenteritis
Interventions: OTHER: Fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel®)|OTHER: Non fermented dairy product (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial Designed to Determine the Safety and Efficacy of EMA401 in Patients With Painful Diabetic Neuropathy
Status: WITHDRAWN
Conditions: Diabetic Neuropathies
Interventions: DRUG: EMA401 600mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protreat-Trial: Prophylactic Antiemetic Treatment of Opioid-induced Nausea and Vomiting (OINV) in Palliative Care
Status: RECRUITING
Conditions: Nausea|Vomiting|Pain|Advanced Cancer
Interventions: DRUG: Palonosetron Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dihydroartemisinin-Piperaquine or Sulphadoxine-Pyrimethamine for the Chemoprevention of Malaria in Sickle Cell Anaemia
Status: COMPLETED
Conditions: Sickle Cell Anemia in Children|Malaria
Interventions: DRUG: Dihydroartemisinin Piperaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Methylene Blue vs Cyanokit for Intraoperative Vasoplegic Syndrome in Liver Transplant Patients
Status: COMPLETED
Conditions: Vasoplegic Syndrome|Liver Transplant; Complications
Interventions: DRUG: Hydroxocobalamin|DRUG: Methylene Blue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Duplex Scanning and Single Photon Emission Computer Tomography (SPECT) in Parkinsonian Syndromes
Status: COMPLETED
Conditions: Parkinson's Disease|Parkinsonian Syndrome|Multiple System Atrophy|Supranuclear Palsy, Progressive|Essential Tremor|Vascular Parkinsonism|Drug Induced Parkinsonism
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antimicrobial Dressing Versus Standard Dressing in Obese Women Undergoing Cesarean Delivery
Status: COMPLETED
Conditions: Cesarean Section Complications|Wound Breakdown|Wound Infection|Satisfaction|Surgical Wound Infection
Interventions: COMBINATION_PRODUCT: ReliaTect™ Post-Op Dressing (contains chlorohexidine gluconate or CHG)|OTHER: Standard Wound Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Copaxone Administered in Combination With N-Acetylcysteine
Status: COMPLETED
Conditions: Relapse Remitting Multiple Sclerosis
Interventions: DRUG: Glatiramer Acetate, N-Acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enoxaparin for Primary Thromboprophylaxis in Ambulatory Patients With COVID-19
Status: TERMINATED
Conditions: COVID-19|Pulmonary Embolism, Deep Vein Thrombosis
Interventions: DRUG: Enoxaparin 40Mg/0.4Ml Inj Syringe 0.4Ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
Status: NOT_YET_RECRUITING
Conditions: High Grade Glioma|Diffuse Intrinsic Pontine Glioma|Anaplastic Astrocytoma|Infant Type Hemispheric Glioma|Glioblastoma|Glioblastoma Multiforme|WHO Grade III Glioma|WHO Grade IV Glioma|Diffuse Midline Glioma, H3K27-altered
Interventions: DRUG: Lorlatinib|DRUG: Lorlatinib with chemotherapy1|DRUG: Lorlatinib with chemotherapy 2|DRUG: Lorlatinib post Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Study of the Safety, Tolerability, Pharmacokinetics and Effect on Renal Potassium Clearance
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: LY2623091|DRUG: Placebo|DRUG: Eplerenone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy Study to Treat Bacterial Vaginosis
Status: COMPLETED
Conditions: Bacterial Vaginosis
Interventions: DRUG: Product 55394|DRUG: Placebo Vehicle (non-treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Doxorubicin and Cyclophosphamide With or Without Intermittent Sunitinib in the First-line Treatment of Locally Advanced or Metastatic Breast Cancer Patients With Measurable Primary Breast Tumor
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Arm A|DRUG: Arm B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Flat Polyp Detection Using New Narrow Band Imaging (NBI) Compared to White Light Colonoscopy - The FIND FLAT Colonoscopy Study
Status: COMPLETED
Conditions: Colorectal Neoplasms|Colonic Polyps|Colorectal Cancer
Interventions: DEVICE: Olympus Colonoscope CFHQ190AL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Optimized Psycho-oncological Care Through an Interdisciplinary Care Algorithm
Status: RECRUITING
Conditions: Psycho-Oncology|Visceral Cancer|Screening|Psychosocial Stressor
Interventions: OTHER: OptiScreen training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Cognitive Decline|Healthy Aging
Interventions: DIETARY_SUPPLEMENT: melatonin|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Evonail® Solution in the Prevention of Nail Damage Induced by Docetaxel in Patients With Breast Cancer.
Status: COMPLETED
Conditions: Breast Carcinoma
Interventions: DEVICE: Evonail|DEVICE: Placebo excipient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intramuscular Diclofenac in the Prevention of Post-ERCP Pancreatitis
Status: COMPLETED
Conditions: Post ERCP Pancreatitis
Interventions: DRUG: Diclofenac|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Adalimumab in Japanese Subjects With Moderately to Severely Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: BIOLOGICAL: adalimumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: D-PLEX 312 - Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection (SHIELD II)
Status: RECRUITING
Conditions: Surgical Site Infection|Colon Surgery|Abdominal Surgery|Post-Op Infection
Interventions: DRUG: D-PLEX|OTHER: Standard of Care (SoC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Saffron as Anti Inflammatory In Patients With Inflammatory Bowel Disease
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Saffron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The RAMP Study - Rejuvenation of the Aging Microbiota With Prebiotics
Status: COMPLETED
Conditions: Microbiome|Immune Function|Inflammation
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Prebiotic supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acceleration of Insulin Action by Hyaluronidase During Closed-Loop Therapy
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: ePID closed loop system|DRUG: hyaluronidase|DRUG: Lispro-PH20
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Anesthesia Methods on CTCs in TURBT Patients
Status: NOT_YET_RECRUITING
Conditions: Bladder Cancer
Interventions: PROCEDURE: General Anesthesia|PROCEDURE: Spinal Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety Study of XL765 (SAR245409) in Combination With Erlotinib in Adults With Solid Tumors
Status: COMPLETED
Conditions: Cancer|Non-Small Cell Lung Cancer
Interventions: DRUG: XL765 (SAR245409)|DRUG: erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial Stewardship Through MRSA Diagnosis in Emergency Department (ED) Patients With Abscesses
Status: COMPLETED
Conditions: Cutaneous Abscess
Interventions: DEVICE: Xpert MRSA/SA SSTI|DIAGNOSTIC_TEST: Standard culture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Randomized Control Trial to Compare Standard Monitoring and Plethysmographic Variability Index-Guided Fluid Therapy In 64 Severe Traumatic Brain Injury Patients, Aged 18 to 60 Years Old Undergoing Emergency Craniotomies
Status: COMPLETED
Conditions: Severe Traumatic Brain Injury
Interventions: DEVICE: Plethymographic Variability Index|DEVICE: Standard Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of KHK2823 in Patients With Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: KHK2823
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Use of Genetic Markers in the Choice of the Pharmacological Treatment of Smoking (GENTSMOKING)
Status: COMPLETED
Conditions: Smoking Cessation|Genetic Predisposition
Interventions: DRUG: Varenicline Tartrate or bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of the Epigenetic Modifying Effects of CC-486 (Oral Azacitidine) in Combination With Fulvestrant
Status: TERMINATED
Conditions: Breast Neoplasms
Interventions: DRUG: CC-486|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intracameral Phenylephrine/Ketorolac on Intraoperative Pain
Status: WITHDRAWN
Conditions: Pain Reduction
Interventions: DRUG: 1% preservative-free lidocaine|DRUG: Phenylephrine 1.0%/ Ketorolac 0.3%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab in Patients Failing to Respond to or Relapsing After CAR T Cell Therapy for Relapsed or Refractory Lymphomas
Status: COMPLETED
Conditions: CD19+ Diffuse Large B-cell Lymphomas|Follicular Lymphomas|Mantle Cell Lymphomas
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of Two Different Oral Doses of NP031112 Versus Placebo in the Treatment of Patients With Mild-to-Moderate Progressive Supranuclear Palsy
Status: COMPLETED
Conditions: Progressive Supranuclear Palsy
Interventions: DRUG: tideglusib|DRUG: tideglusib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperthermic Intraoperative Intraperitoneal Chemotherapy of Recurrent Ovarian Cancer - A Feasibility Study
Status: TERMINATED
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Carcinoma
Interventions: PROCEDURE: Hyperthermic intraoperative intraperitoneal chemotherapy|PROCEDURE: Cytoreduction|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Stereotactic Ablative Radiotherapy (SABR) in Elderly Stage I NSCLC
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer
Interventions: RADIATION: Stereotactic Ablative Radiotherapy (SABR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Progesterone Treatment for Cocaine-dependent Women: A Pilot Study
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: Oral micronized progesterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Early Eating and Stair Climbing on Body Composition
Status: NOT_YET_RECRUITING
Conditions: eTRE (Early Time Restricted Eating)|eTRE With BISC (Brief Intense Stair Climbing)
Interventions: BEHAVIORAL: eTRE|BEHAVIORAL: eTRE with BISC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT