pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Glycaemic Response to a Liquid Meal Tolerance Test
Status: COMPLETED
Conditions: Glycaemic Index|Glycaemic Response
Interventions: OTHER: Control Drink|OTHER: Experimental Drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long-Term Effects of Task-Oriented Lower Extremity Strengthening Training
Status: COMPLETED
Conditions: Ischemic Cerebrovascular Accident
Interventions: BEHAVIORAL: Task-Oriented Lower Extremity Strengthening Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Of Sunitinib Malate Versus Sorafenib In Patients With Inoperable Liver Cancer
Status: TERMINATED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: sunitinib malate|DRUG: sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Safety and Efficacy of T92 in Pediatric Patients With Tourette Syndrome
Status: NOT_YET_RECRUITING
Conditions: Tourette Syndrome in Children|Tourette Syndrome in Adolescence
Interventions: DIETARY_SUPPLEMENT: T92|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate Nilotinib in Chronic Myelogenous Leukemia (CML) Patients With SubOptimal Response
Status: COMPLETED
Conditions: Philadelphia Chromosome Positive|Chronic Myelogenous Leukemia in Chronic Phase
Interventions: DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bright Light Therapy on Post-stroke Insomniawith Post-stroke Insomnia
Status: COMPLETED
Conditions: Stroke Sequelae
Interventions: DEVICE: Philips EnergyUp Energy light HF3418/01|DEVICE: Philips EnergyUp Energy light HF3418/01 with filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cytokine REmoval in CRitically Ill pAtients Requiring Surgical Therapy for Infective Endocarditis (RECReATE)
Status: RECRUITING
Conditions: Endocarditis|Sepsis|Septic Shock
Interventions: OTHER: Treatment protocol with adsorption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CCI-779 in Treating Patients With Soft Tissue Sarcoma or Gastrointestinal Stromal Tumor
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumor|Recurrent Adult Soft Tissue Sarcoma|Stage I Adult Soft Tissue Sarcoma|Stage II Adult Soft Tissue Sarcoma|Stage III Adult Soft Tissue Sarcoma|Stage IV Adult Soft Tissue Sarcoma
Interventions: DRUG: temsirolimus|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Ancrod for the Treatment of Acute Ischemic Stroke Within 6 Hours After Onset of Symptoms
Status: COMPLETED
Conditions: Brain Infarction|Cerebral Ischemia|Acute Stroke
Interventions: DRUG: Ancrod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Biocollection on Peripheral Inflammation
Status: RECRUITING
Conditions: Schizoaffective Disorder, Depressive Type|Bipolar Disorder I|Bipolar Disorder II
Interventions: BIOLOGICAL: Peripheral venipuncture blood sampling, as part of standard care procedures|OTHER: Interview with a psychiatrist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Durvalumab (MEDI4736) Plus Tremelimumab for Advanced Neuroendocrine Neoplasms of Gastroenteropancreatic or Lung Origin
Status: COMPLETED
Conditions: Neuroendocrine Tumors|Neuroendocrine Neoplasm of Lung
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This is a Single Ascending Dose Tolerance Study
Status: TERMINATED
Conditions: Cognition Disorders
Interventions: DRUG: SLV354 capsules|DRUG: SLV354 capsules|DRUG: SLV354 capsules|DRUG: SLV354 capsules|DRUG: SLV354 capsules|DRUG: SLV354 capsules|DRUG: SLV354 capsules|DRUG: SLV354 capsules|DRUG: Placebo capsules|DRUG: SLV354 capsules|DRUG: SLV354 capsules|DRUG: SLV354 capsules|DRUG: SLV354 capsules|DRUG: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mycophenolate Mofetil (MMF) in Patients With IgA Nephropathy
Status: TERMINATED
Conditions: IgA Nephropathy
Interventions: DRUG: Mycophenolate Mofetil (MMF)|DRUG: MMF Placebo|DRUG: ACEi|DRUG: FOS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Modulatory Profiles in Massage for Healthy Participants
Status: COMPLETED
Conditions: Healthy|Musculoskeletal Pain
Interventions: OTHER: Pain Inducing Massage|OTHER: Pain Free Massage|OTHER: Coldpressor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Evaluation of Florbetapir F 18 (18F-AV-45)
Status: COMPLETED
Conditions: Alzheimer Disease|Mild Cognitive Impairment|Neurodegenerative Diseases
Interventions: DRUG: Florbetapir F 18
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment for Depressed, Obese Individuals at Risk for Cardiovascular Disease (CVD)
Status: COMPLETED
Conditions: Obesity|Major Depressive Disorder|Dysthymic Disorder|Cardiovascular Disease
Interventions: BEHAVIORAL: Behavior Modification for Weight Loss|BEHAVIORAL: Alternative Approach to Weight Loss|BEHAVIORAL: Cognitive-Behavior Therapy for Depression|BEHAVIORAL: Depression Support and Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Biopsy Needles for Endoscopic Ultrasound Guided Samples for Pancreatic Masses
Status: COMPLETED
Conditions: Pancreatic Neoplasm
Interventions: DEVICE: Acquire EUS Biopsy Device|DEVICE: Expect EUS Aspiration Needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Probiotics on Exercise Performance and Recovery
Status: RECRUITING
Conditions: Probiotics|Acute Exercise
Interventions: DIETARY_SUPPLEMENT: Probiotic Supplement|OTHER: Placebo Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Degenerative Lumbar Stenosis Conservative Treatment
Status: UNKNOWN
Conditions: Spinal Stenosis Lumbar|Spinal Canal Stenosis
Interventions: COMBINATION_PRODUCT: Goldic serum|DRUG: Steroid injections|PROCEDURE: Manual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating LIFUP in Anhedonic Depression
Status: ENROLLING_BY_INVITATION
Conditions: Depression|Anhedonia
Interventions: DEVICE: Low Intensity Focused Ultrasound Pulsation (LIFUP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Dietary Proteins on Postprandial Lipaemia and Incretin Responses in Obese Subjects
Status: COMPLETED
Conditions: Postprandial Lipaemia|Postprandial Incretins|Postprandial Inflammation
Interventions: DIETARY_SUPPLEMENT: Casein|DIETARY_SUPPLEMENT: Whey Isolate|DIETARY_SUPPLEMENT: Whey Hydrolysate|DIETARY_SUPPLEMENT: Alphalact-Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Safety and Efficacy of RegenKit Autologous PRP Gel for the Treatment of Diabetic Foot Ulcer
Status: UNKNOWN
Conditions: Diabetic Foot Ulcers
Interventions: DEVICE: Autologous platelet rich plasma gel|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody Therapy in Treating Patients With Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: RADIATION: tositumomab and iodine I 131 tositumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cord Blood Derived CAR-T Cells in Refractory/Relapsed B Cell Malignancies
Status: UNKNOWN
Conditions: Refractory|Relapsed|B Cell Lymphoma|B Cell Leukemia
Interventions: BIOLOGICAL: CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-term Treatment With B-VEC for Dystrophic Epidermolysis Bullosa
Status: COMPLETED
Conditions: Dystrophic Epidermolysis Bullosa|DEB - Dystrophic Epidermolysis Bullosa|Recessive Dystrophic Epidermolysis Bullosa|Dominant Dystrophic Epidermolysis Bullosa
Interventions: BIOLOGICAL: Open Label Topical Beremagene Geperpavec (B-VEC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Effect of Nipocalimab on Vaccine Responses in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nipocalimab|BIOLOGICAL: Tdap|BIOLOGICAL: PPSV23
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Extension of the MIME Robotic System for Stroke Rehabilitation
Status: COMPLETED
Conditions: Stroke|Impaired Upper Extremity Function
Interventions: DEVICE: robotic therapy|OTHER: conventional functional training|DEVICE: robotic therapy|OTHER: conventional functional training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Study Efficacy and Safety of Tobradex Eye Drop Suspension vs Tobramycin/Dexamethasone Ophthalmic Suspension
Status: UNKNOWN
Conditions: Blepharo Conjunctivitis
Interventions: DRUG: Tobramycin/dexamethasone opthalmic solution|DRUG: Tobradex Opthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MITO-5: Weekly Carboplatin and Paclitaxel as First Line Chemotherapy for Elderly Patients With Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Randomized Multi-Center Study of Using the Hyper-CL™ Lens in Subjects Suffering From Bacterial Keratitis
Status: COMPLETED
Conditions: Bacterial Keratitis
Interventions: DEVICE: Hyper-CL™ lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beamion LUNG-2: A Study to Test Whether Zongertinib (BI 1810631) Helps People With Advanced Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatment
Status: RECRUITING
Conditions: Lung Cancer, Non-squamous, Non-small Cell
Interventions: DRUG: zongertinib|DRUG: pembrolizumab|DRUG: cisplatin|DRUG: carboplatin|DRUG: pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Maxillary Canine Retraction Using Self-ligating Brackets System Assisted With Micro-osteoperforations
Status: ENROLLING_BY_INVITATION
Conditions: Accerleration of Tooth Movement
Interventions: BIOLOGICAL: self ligating bracket with micro osteoperforation|BIOLOGICAL: conventional bracket with micro osteoperforation|BIOLOGICAL: conventional bracket without micro osteoperforation|BIOLOGICAL: self ligating bracket without micro osteoperforation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STEP 6: Research Study Investigating How Well Semaglutide Works in People Living With Overweight or Obesity
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DRUG: Semaglutide|DRUG: Placebo (semaglutide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Survival Rate and Treatment Cost in Patients With Pancreatic Cancer With the Advent of New Chemotherapeutic Agents in Korea: An Analysis Using NHIS Database and K-PaC Registry Focusing on the Newest One, Liposomal Irinotecan
Status: RECRUITING
Conditions: Pancreatic Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immuno Positron Emission Tomography Study of GSK2849330 in Subjects With Human Epidermal Growth Factor Receptor 3-Positive Solid Tumors
Status: COMPLETED
Conditions: Cancer|Neoplasms
Interventions: DRUG: GSK2849330|DRUG: 89Zr-GSK2849330
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The PAtient-Centred Team - Effectiveness and Cost-effectiveness Study
Status: UNKNOWN
Conditions: Frail Elderly w/ Multimorbidity & Functional Limitations
Interventions: OTHER: Integrated care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Effect of Selpercatinib (LY3527723) on Corrected QT (QTc) Interval in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Selpercatinib|DRUG: Moxifloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Study of Benazepril HCl / Hydrochlorothiazide 20 mg/ 25 mg Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Benazepril HCl/ Hydrochlorothiazide 20 mg/ 25 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Performance Enhancement and Non-Invasive Brain Stimulation
Status: COMPLETED
Conditions: Executive Function|Motor Activity|Brain Stimulation
Interventions: DEVICE: Transcranial Direct Current Stimulation|BEHAVIORAL: Working Memory Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Seroquel Alone Versus Seroquel With an SSRI for Depression With Psychotic Symptoms
Status: TERMINATED
Conditions: Major Depressive Disorder With Psychotic Features
Interventions: DRUG: Quetiapine|DRUG: escitalopram|DRUG: Sertraline|DRUG: Citalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ARCH II Study (Alcohol Research Center on HIV Study II)
Status: COMPLETED
Conditions: Alcohol Consumption|HIV|Motivation
Interventions: BEHAVIORAL: Motivational Interviewing|OTHER: Questionnaire assessment|OTHER: Neurocognitive assessments|OTHER: Blood specimens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Safety and Potential Therapeutic Effects of Cordstem-ST in Patients With Cerebral Infarction
Status: COMPLETED
Conditions: Cerebral Infarction
Interventions: BIOLOGICAL: Cordstem-ST|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomized Trial Comparing Partial Hepatectomy and TACE Plus PEI for Small Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: OTHER: operation;TACE plus PEI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Anti-Giardia and Antihelmintic Treatment on Infant Growth in Bangladesh
Status: COMPLETED
Conditions: Giardiasis
Interventions: DRUG: Anti-Giardia and antihelmintic treatment (secnidazole or albendazole)|DRUG: Anti-Giardia treatment only (secnidazole or albendazole)|DRUG: Control group (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Magnetic-assisted Capsule Endoscope With 3D Images in EV Detection in Cirrhotic Patient
Status: UNKNOWN
Conditions: Esophageal Varices in Cirrhosis of the Liver
Interventions: DEVICE: magnetic-assisted capsule endoscope system (InsightEyes EGD System) with or without 3D images
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Status: COMPLETED
Conditions: Solid Tumor|Breast Cancer|Cancer of Head and Neck
Interventions: DRUG: RO6874281|DRUG: Trastuzumab|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Collatamp G Antibiotic Impregnated Sponges in the Treatment of Peri-prosthetic Total Joint Infections
Status: TERMINATED
Conditions: Infection
Interventions: DRUG: Collatamp G sponge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Predictive Factors Affecting the Efficacy of Local Tetracycline Injection for Treatment of Post-mastectomy Seroma.
Status: COMPLETED
Conditions: Post-mastectomty Seroma
Interventions: DRUG: tetracycline mixed with xylocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Contraceptive Awareness and Reproductive Education
Status: COMPLETED
Conditions: Pregnancy|Sexually Transmitted Infections
Interventions: BEHAVIORAL: Motivational Intervention|BEHAVIORAL: Didactic Educational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Multinational, Multicenter, Follow-up Study to Evaluate the Long-term Safety and Efficacy of Brivaracetam
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Brivaracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extreme Challenges - Psychopathology & Treatment Experiences Among Severly Selfharming Inpatients in Norway
Status: COMPLETED
Conditions: Self Harm|Personality Disorders|Psychosis|Developmental Disorder|PTSD|Cognitive Impairment
Interventions: OTHER: Assessment of diagnoses, functioning and health services
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability and Drug- Drug Interaction Study of Ubrogepant With Erenumab or Galcanezumab in Participants With Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Ubrogepant|DRUG: Erenumab|DRUG: Galcanezumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy Study of Acupuncture to Treat the Upper Abdominal Pain of Cancer Patients
Status: COMPLETED
Conditions: Abdominal Pain
Interventions: DEVICE: Acupuncture|PROCEDURE: Neurolytic celiac plexus block (NCPB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Advanced Solid Tumors
Status: RECRUITING
Conditions: Sarcoma|Carcinoma|Breast Cancer|Pancreatic Cancer|Colorectal Cancer|Gastric Cancer|Liver Cancer|Lung Cancer|Gynecologic Cancer
Interventions: DRUG: Recombinant oncolytic herpes simplex virus type 1 (R130)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin + BIBF 1120 in Patients for Ovarian Cancer
Status: TERMINATED
Conditions: Ovarian Cancer
Interventions: DRUG: Doxil (Pegylated Liposomal Doxorubicin)|DRUG: BIBF 1120
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin in Intrahepatic Cholestasis of Pregnancy
Status: UNKNOWN
Conditions: Intrahepatic Cholestases|Pregnancy Complications
Interventions: DRUG: Metformin|DRUG: Ursodeoxycholic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Decitabine for Refractory or Relapsed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Relapsed Acute Myeloid Leukemia
Interventions: DRUG: Pembrolizumab|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Paradoxical Vocal Fold Motion Disorder (PVFMD) With a Form of Respiratory Retraining Technique
Status: COMPLETED
Conditions: Paradoxical Vocal Fold Motion Disorder|Vocal Cord Dysfunction
Interventions: BEHAVIORAL: Respiratory retraining for PVFMD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of a Phytotherapy Combination (Aqualibra) in Patients With Uncomplicated Cystitis
Status: COMPLETED
Conditions: Urinary Tract Infection Lower Acute
Interventions: COMBINATION_PRODUCT: Herbal Medicinal Product|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Doravirine, Tenofovir, Lamivudine (MK-1439A) and ATRIPLA™ in Treatment-Naive Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Participants (MK-1439A-021)
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV)
Interventions: DRUG: Doravirine, Tenofovir, Lamivudine|DRUG: ATRIPLA™|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Food Allergen OIT for Shrimp and Cashew
Status: TERMINATED
Conditions: Allergy;Food|Allergy to Shrimp|Allergy to Cashew Nut (Disorder)
Interventions: DRUG: Cashew or Shrimp Oral Immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Hydroxychloroquine for the Treatment & Prevention of Coronavirus Disease 2019 (COVID-19) Caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
Status: WITHDRAWN
Conditions: Covid19|SARS (Severe Acute Respiratory Syndrome)
Interventions: DRUG: Hydroxychloroquine|DIETARY_SUPPLEMENT: Vitamins and Minerals|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sleepiness and Driving Performances in Adults With Attention-Deficit/ Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: OTHER: Polysomnography|OTHER: Maintenance Wakefulness Test|BEHAVIORAL: Neuropsychological evaluation|OTHER: Driving test on a simulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Detect Unrecognized Mucopolysaccharidosis in Children Visiting Rheumatology, Hand or Skeletal Dysplasia Clinics
Status: TERMINATED
Conditions: Mucopolysaccharidoses|Mucopolysaccharidosis I|Mucopolysaccharidosis II|Mucopolysaccharidosis IV|Mucopolysaccharidosis VI
Interventions: OTHER: Dried blood spot test for MPS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevention of the Age-Related Cognitive Impairment by Exercise and Mental Activity - Berlin Bleibt Fit
Status: UNKNOWN
Conditions: Cognition|Mood
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Mental activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: EUropean Pharmacogenetics of AntiCoagulant Therapy - Phenprocoumon
Status: COMPLETED
Conditions: Venous Thromboembolism (VTE)|Atrial Fibrillation (AF)
Interventions: OTHER: Genotype-guided dosing algorithm|OTHER: Non-genotype-guided dosing algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Melatonin Levels in Smith Magenis Syndrome (SMS)
Status: TERMINATED
Conditions: Chromosome Disorders
Interventions: DIETARY_SUPPLEMENT: Melatonin|DEVICE: Enviro-light artificial light box
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Long-Term, Open-Label, Study on Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: LY2140023|DRUG: Olanzapine|DRUG: Aripiprazole|DRUG: Risperidone|DRUG: Quetiapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Boosting Chinese Healthcare Service Providers' Utilization of Smoking Cessation Interventions by 'WeChat WeQuit' Program
Status: UNKNOWN
Conditions: Smoking Cessation Intervention|Smoking Abstinence
Interventions: BEHAVIORAL: 'WeChat WeQuit' smoking cessation training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Quetiapine Compared With Valproate in the Treatment of Patients With Bipolar Disorder and Rapid Cycling
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: quetiapine fumarate or valproate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Opioid Use and Pain Scores in Patients Undergoing Transforaminal Lumbar Interbody Fusion
Status: TERMINATED
Conditions: Low Back Pain
Interventions: DRUG: Acetaminophen|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Modes of Administration of the IADL Questionnaire, Assessing the Level of Functional Autonomy of Patients to Carry Out the Tasks of Daily Living: Randomized Controlled Trial Among Patients of a Memory Clinic
Status: COMPLETED
Conditions: Alzheimer's Disease|Dementia Disorders
Interventions: OTHER: IADL administration by phone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Vibration for Pain Reduction During Trigger Point Injection
Status: COMPLETED
Conditions: Myofascial Pain Syndromes
Interventions: DEVICE: Vibration|DEVICE: Placebo vibration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carotid and Vertebral Magnetic Resonance Angiography (MRA) Study Comparing Dotarem and Time Of Flight (TOF)
Status: COMPLETED
Conditions: Cerebral Arterial Diseases
Interventions: DRUG: Dotarem|OTHER: TOF MRA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Longitudinal Early Advance Care Planning Discussions and Documentation (LEADD) Program: An Exploratory Study in Adolescents and Young Adults (AYAs) Receiving Hematopoietic Stem Cell Transplant
Status: RECRUITING
Conditions: Hematopoietic Stem Cell Transplantation
Interventions: BEHAVIORAL: Advance Care Planning conversations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Acupuncture for Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Status: COMPLETED
Conditions: Chronic Prostatitis
Interventions: DEVICE: Acupuncture|DEVICE: placebo needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methylprednisolone Versus Dexamethasone in Pediatric Caudal Block
Status: RECRUITING
Conditions: Caudal Block
Interventions: DRUG: caudal block using dexamethasone|DRUG: caudal block using methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of GABAergic Transmission in Auditory Processing in Autism Spectrum Disorder
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: Continuous Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Functional Electrical Stimulation of the Bilaterally Paralyzed Human Larynx
Status: ACTIVE_NOT_RECRUITING
Conditions: Bilateral Vocal Fold Paralysis (BVFP)
Interventions: DEVICE: Laryngeal Pacing Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: To Evaluate the Clinical Efficacy of Iguratimod in the Treatment of IgG4 Related Disease (IgG4-RD) With Mild Symptom
Status: UNKNOWN
Conditions: IgG4-related Disease
Interventions: DRUG: T 614
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib With TACE to Treat Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sorafenib|PROCEDURE: Transarterial chemoembolisation with doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of the Human Cytomegalovirus (CMV) Vaccine (V160) in Healthy Japanese Men (V160-003)
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: BIOLOGICAL: V160|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Critical Periods After Stroke Study (CPASS)
Status: UNKNOWN
Conditions: Stroke|Brain Infarction|Brain Ischemia|Cerebral Infarction|Cerebrovascular Disorders
Interventions: BEHAVIORAL: Early Intensive upper extremity motor training|BEHAVIORAL: Sub-acute intensive upper extremity motor training|BEHAVIORAL: Chronic intensive upper extremity motor training|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Leukocytapheresis (LCAP) in Patients With Ulcerative Colitis (UC)
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DEVICE: Cellsorba EX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrating Fall Prevention Balance Exercises Into a Program for Older Adults With Peripheral Artery Disease (PAD): A Mixed Methods Feasibility Study
Status: COMPLETED
Conditions: Fall|Fall Injury|Peripheral Artery Disease|Peripheral Arterial Disease
Interventions: BEHAVIORAL: Adapted Otago Exercise Program (OEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Phase II Trial of Anastrozole Plus Metronomic Tegafur-uracil as Neo-adjuvant Therapy in Postmenopausal Breast Cancer
Status: TERMINATED
Conditions: Breast Neoplasms
Interventions: DRUG: Anastrozole|DRUG: Anastrozole plus tegafur-uracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Erenumab (AMG 334) in Migraine Prevention
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Erenumab|DRUG: Placebo|DRUG: Erenumab PFS|DRUG: Erenumab AI/Pen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Low Dose Versus Aggressive Inhibition of the Renin-Angiotensin-Aldosterone (RAS) to Treat Microalbuminuria
Status: COMPLETED
Conditions: Microalbuminuria
Interventions: DRUG: benazepril|DRUG: benazepril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of ABSK021 in Patients With Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Advanced Pancreatic Cancer
Interventions: DRUG: Pimicotinib (ABSK021)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre Operative Transversus Abdominis Plane Block Laparoscopic Gynecological Surgery
Status: COMPLETED
Conditions: Pain|Surgery
Interventions: PROCEDURE: Transversus abdominis plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Testing the Addition of Tazemetostat to the Immunotherapy Drug, Pembrolizumab (MK-3475), in Advanced Urothelial Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Urothelial Carcinoma|Metastatic Urothelial Carcinoma|Stage III Bladder Cancer AJCC v8|Stage IV Bladder Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Pembrolizumab|DRUG: Tazemetostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintaining Mechanical Ventilation During Cardiopulmonary Bypass for Cardiac Surgery
Status: COMPLETED
Conditions: Cardiopulmonary Bypass
Interventions: DEVICE: Maintaining mechanical ventilation during surgery|DEVICE: Absence of mechanical ventilation during surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Awakening Versus Bedtime Dosing of Ramipril in Subjects With Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Ramipril|DEVICE: ambulatory blood pressure monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double-masked Study of Netarsudil (AR-13324) Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: AR-13324 Ophthalmic Solution 0.02%|DRUG: Timolol Maleate Ophthalmic Solution 0.5% BID|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of BAF312 in Dermatomyositis
Status: TERMINATED
Conditions: Active Dermatomyositis
Interventions: DRUG: BAF312|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the Combination of Symptoms and Symptoms With General Treatment for Acute Hemorrhagic Stroke
Status: UNKNOWN
Conditions: Acute Hemorrhagic Stroke
Interventions: DRUG: Xingnaojing injection + Shuxuetong oral liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Raltegravir During the Third Trimester of Pregnancy
Status: COMPLETED
Conditions: HIV-1 Infection|PREGNANCY
Interventions: OTHER: Study of pharmacokinetic properties of raltegravir during the 3rd trimester of pregnancy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Transitional Cell Cancer of the Urothelium
Status: COMPLETED
Conditions: Bladder Cancer|Transitional Cell Cancer of the Renal Pelvis and Ureter|Urethral Cancer
Interventions: DRUG: carboplatin|DRUG: gemcitabine hydrochloride|DRUG: methotrexate|DRUG: vinblastine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Subfoveal Choroidal Thickness After Surgery for Age-related Cataracts
Status: COMPLETED
Conditions: Cataract
Interventions: PROCEDURE: Femtosecond laser-assisted cataract surgery|PROCEDURE: Conventional phacoemulsification cataract surgery|DRUG: Tropicamide|DRUG: Proparacaine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Muscle Training in Patients With Interstitial Lung Disease
Status: COMPLETED
Conditions: Interstitial Fibrosis|Pulmonary Disease|Interstitial Lung Disease|Sarcoidosis|Idiopathic Pulmonary Fibrosis|Pneumonia, Interstitial
Interventions: OTHER: Inspiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Transversal Multiaxial Evaluation and 5-year Follow-up of a Cohort of French Gamblers (JEU)
Status: COMPLETED
Conditions: Pathological or "at Risk" Gambling
Interventions: OTHER: Summons of patients and filling questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: OTHER
Clinical trial: Ulcerative Colitis Endoscopic Index of Severity and Fecal Calprotectin to Predict the Reaction to Corticosteroids of Acute Severe Ulcerative Colitis
Status: UNKNOWN
Conditions: Acute Severe Colitis (ASC)
Interventions: DRUG: corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant TACiE in Locally Advanced Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Teysuno|PROCEDURE: Transarterial chemoembolization (TACE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of PRX-08066 in Patients With Pulmonary Hypertension and Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Hypertension|Chronic Obstructive Pulmonary Disease
Interventions: DRUG: PRX-08066
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Nevanac 3-Month Safety Study With QID Dosing
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Nepafenac ophthalmic solution 0.1%|DRUG: Ketorolac Tromethamine ophthalmic solution 0.4%|OTHER: Nepafenac ophthalmic suspension vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Exercise and Diet in Type 2 Diabetic Women
Status: COMPLETED
Conditions: Insulin Sensitivity|Type 2 Diabetes
Interventions: BEHAVIORAL: Standard life style modification for type 2 diabetes|BEHAVIORAL: Diet restriction|BEHAVIORAL: Exercise|BEHAVIORAL: Diet and exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers
Status: COMPLETED
Conditions: Ewing Sarcoma|PEComa|Epithelioid Sarcoma|Desmoid Tumor|Chordoma|Non Small Cell Lung Cancer|Urothelial Carcinoma|Melanoma|Renal Cell Carcinoma|Squamous Cell Carcinoma|Hepatocellular Carcinoma|Classical Hodgkin Lymphoma|Colorectal Cancer|MTOR Activating Mutation
Interventions: DRUG: Nab-Rapamycin|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Spinal Manipulation in Patients With Nonspecific Low Back Pain
Status: COMPLETED
Conditions: Back Pain|Lumbar Pain Syndrome|Back Pain, Low
Interventions: OTHER: Spinal Manipulation + exercise program|OTHER: Spinal manipulation + Kinesiotaping|OTHER: spinal manipulation + respiratory exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: BRAIN-targeted Goal-directed Therapy in High-risk Patients undeRgOing Major electIve SurgEry: the BRAIN-PROMISE Study
Status: UNKNOWN
Conditions: Surgery|Perioperative Complication
Interventions: DEVICE: Near Infrared Spectroscopy (NIRS)|DEVICE: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Open-Label Extension Study of MCS-2 in the Treatment of Lower Urinary Tract Symptoms
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms|Benign Prostatic Hyperplasia
Interventions: DRUG: MCS-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of MP-3180 in Healthy Volunteers
Status: COMPLETED
Conditions: Glomerular Filtration Rate|Acute Kidney Injury
Interventions: DRUG: MP-3180|OTHER: Iohexol comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Compare PK, PD and Safety of CKD-382 in Healthy Subjects
Status: UNKNOWN
Conditions: GERD
Interventions: DRUG: CKD-382(formulation I)|DRUG: CKD-382(formulation II)|DRUG: D026
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Dose Monitoring (TDM) of Tamoxifen
Status: UNKNOWN
Conditions: Breast Cancer|Breast Carcinoma|Breast Tumors|Cancer of Breast|Malignant Neoplasm of Breast
Interventions: DRUG: Tamoxifen 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Omega-3 Fatty Acids on Peripheral Arterial Disease II
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DIETARY_SUPPLEMENT: Pro-Omega|OTHER: ProOmega Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Cemiplimab, or Cemip-Chemo Followed by Biomarker-guided Treatment for Pts w/HPV H&N Ca
Status: RECRUITING
Conditions: HPV-Related Squamous Cell Carcinoma
Interventions: DRUG: Cemiplimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing the Overall Risk Level in Patients Suffering From Metabolic Syndrome
Status: COMPLETED
Conditions: Hypertension, Dyslypidaemia
Interventions: DRUG: Fluvastatin|DRUG: Valsartan|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Influence on the Level of Perioperative Blood Glucose and Insulin of Elderly Diabetes Patients
Status: UNKNOWN
Conditions: Perioperative Blood Glucose and Insulin
Interventions: DRUG: general anesthesia induction|DRUG: Isoflurane|DRUG: Dexmedetomidine|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clofarabine/Ara-C Treatment Combined With Reduced-intensity Conditioning Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia in Primary Treatment Failure
Status: COMPLETED
Conditions: AML
Interventions: DRUG: Clofarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of IBI-10090 in Cataract Surgery Patients
Status: TERMINATED
Conditions: Ocular Inflammation
Interventions: DRUG: IBI-10090
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT