pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: MBM-02 (Tempol) for the Treatment of Glioblastoma Multiforme (GBM)
Status: UNKNOWN
Conditions: Glioblastoma|Glioblastoma Multiforme
Interventions: DRUG: MBM-02
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gingival Inflammatory Response,Bacterial Adhesion and Patient Satisfaction of Ceramo-metallic vs Zirconia Crowns
Status: UNKNOWN
Conditions: Gingival Inflammation|Oral Bacterial Infection
Interventions: OTHER: ceramo-metallic crown prepartion|OTHER: full anatomical monolithic zirconia crown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-escalation Study of Single Dose GHB04L1 in Healthy Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GHB04L1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Discerning Symptomatic and Asymptomatic Episodes Pre and Post Radiofrequency Ablation of Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Implantable Loop Recorder (ILR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial of Maraviroc (UK-427,857) in Combination With Optimized Background Therapy Versus Optimized Background Therapy Alone for the Treatment of HIV-1 Infected Subjects
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Maraviroc (UK-427,857)|DRUG: Optimized Background Therapy|DRUG: Optimized Background Therapy|DRUG: Placebo|DRUG: Optimized Background Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Aminophylline More Effective Than Neostigmine/Atropine Mixture in the Treatment of Post-dural Puncture Headache
Status: COMPLETED
Conditions: Post-Dural Puncture Headache
Interventions: DRUG: IV Aminophylline|DRUG: IV Neostigmine Methylsulfate + Atropine Sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety of Lebrikizumab Compared to Topical Corticosteroids in Adult Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Lebrikizumab|DRUG: Topical Corticosteroid Creams (Triamcinolone acetonide 0.1% and Hydrocortisone 2.5%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel PI3K Delta Inhibitor TGR-1202, in Combination With Brentuximab Vedotin for Hodgkin's Lymphoma Patients
Status: COMPLETED
Conditions: Hodgkin's Lymphoma
Interventions: DRUG: TGR-1202 + brentuximab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combining MRI Steatosis Assessment and Transient Elastography to Improve Liver Fibrosis Diagnosis in Non Alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: PROCEDURE: Liver biopsy|DEVICE: Abdominal MRI|DEVICE: Transient elastography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Can the Assessment of the Subhippocampal Region Contribute to the Detection of Early Diagnosis of Alzheimer's Disease? A Validation Study Using PET With Florbetapir (AV-45).
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: DEVICE: PET amyloid tracer (Florbetapir F18 AV45 F18
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prosperando: Fostering Resilience on Dialysis
Status: COMPLETED
Conditions: Racial/Ethnic Minorities on Dialysis
Interventions: BEHAVIORAL: Active Comparator: peer navigator|OTHER: Placebo Comparator: Control Arm (standard of care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
Status: RECRUITING
Conditions: Ulcerative Colitis|Ulcerative Colitis Chronic|Inflammatory Bowel Diseases|Crohn's Disease
Interventions: DRUG: Mirikizumab|DRUG: Mirikizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Thoracic Facet Joint Nerve Blocks
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: Thoracic facet joint nerve blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of Product Use in Smokers Switching From Cigarettes to a RELX Electronic Nicotine Delivery System
Status: COMPLETED
Conditions: Electronic Cigarette Use
Interventions: OTHER: RELX ENDS Tobacco Flavor|OTHER: RELX ENDS Menthol Flavor|OTHER: RELX ENDS Tobacco and Menthol Flavors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Comparison of Two Dose Levels of Indinavir Combined With Two Nucleoside Analogue Reverse Transcriptase Inhibitors (NRTIs) in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect and Cost Effectiveness of a Dyadic Empowerment-based Heart Failure Management Program for Self-care
Status: RECRUITING
Conditions: Heart Failure|Self Care|Empowerment|Transitional Care|Disease Management
Interventions: OTHER: Dyadic empowerment based heart failure management program|OTHER: Dyadic education program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: GlideRite® Rigid Stylet Versus Parker Flex-It Stylet
Status: COMPLETED
Conditions: Anesthesia
Interventions: DEVICE: Glide Rite Rigid Stylet group|DEVICE: Parker Flex-It directional stylet group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Research Study of How the Medicine NNC0480-0389 Taken With Semaglutide Works in the Body of Healthy Japanese Men
Status: COMPLETED
Conditions: Healthy Volunteers Type 2 Diabetes
Interventions: DRUG: NNC0480-0389|DRUG: Placebo (NNC0480-0389)|DRUG: Semaglutide|DRUG: Placebo (Semaglutide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BeatMG: Phase II Trial of Rituximab In Myasthenia Gravis
Status: COMPLETED
Conditions: Myasthenia Gravis
Interventions: DRUG: Rituximab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Open-label Trial of Two ABC/3TC Based Regimens in Late Presenter naïve Patients (CD4 <200 Cells/µL)
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: abacavir/lamivudine + raltegravir|DRUG: abacavir/lamivudine + darunavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Advanced Renal Cell Cancer Combination ImmunoThErapy Clinical Trial
Status: RECRUITING
Conditions: Advanced Renal Cell Carcinoma
Interventions: DRUG: Botensilimab|DRUG: Balstilimab|DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predischarge Bundle to Minimize Negative Impact on Quality of Life of Nuisance Bleedings
Status: COMPLETED
Conditions: Myocardial Ischemia|Hemorrhage|Quality of Life|Platelet Aggregation Inhibitors
Interventions: BEHAVIORAL: good clinical practice|BEHAVIORAL: bundle group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Environmental Exposure to Lead and Its Health Effects on Patients With Maintenance Hemodialysis
Status: UNKNOWN
Conditions: Anemia|Malnutrition|Inflammation|Lead Poisoning
Interventions: DRUG: lead chelation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of a Candidate COVID-19 Vaccine (COV001)
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronavirus
Interventions: BIOLOGICAL: ChAdOx1 nCoV-19|BIOLOGICAL: MenACWY|BIOLOGICAL: ChAdOx1 nCoV-19 full boost|BIOLOGICAL: ChAdOx1 nCoV-19 half boost|BIOLOGICAL: MenACWY boost|DRUG: Paracetamol|BIOLOGICAL: ChAdOx1 nCoV-19 0.5mL boost|BIOLOGICAL: ChAdOx1 nCoV-19 0.5mL (3.5-6.5x10^10vp) late vaccine (LV)|BIOLOGICAL: ChAdOx1 nCoV-19 0.5mL (3.5-6.5x10^10vp) late vaccine two (LVT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Comparison of Two Minimally Invasive Tooth Extraction Systems
Status: COMPLETED
Conditions: Tooth Extraction Status Nos
Interventions: PROCEDURE: Tooth extraction|DEVICE: Benex|DEVICE: Physics Forceps|DEVICE: Conventional Extraction Forceps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Per Oral Endoscopic Myotomy (POEM) in Patients Suffering From Achalasia
Status: COMPLETED
Conditions: Achalasia
Interventions: PROCEDURE: Procedure: Per Oral Endoscopic Myotomy (POEM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene-Modified T Cells, Vaccine Therapy, and Ipilimumab in Treating Patients With Locally Advanced or Metastatic Malignancies
Status: TERMINATED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: cyclophosphamide|DRUG: fludarabine phosphate|BIOLOGICAL: NY-ESO-1 reactive TCR retroviral vector transduced autologous PBL|BIOLOGICAL: dendritic cell vaccine therapy|BIOLOGICAL: aldesleukin|RADIATION: fludeoxyglucose F 18|PROCEDURE: positron emission tomography|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Quetiapine on Brain Activity Patterns in Patients With Heightened Risk of Bipolar Disorder
Status: UNKNOWN
Conditions: Depression|Bipolar Disorder
Interventions: DRUG: Quetiapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immediate Implant Placement in Fresh Extraction Sockets and Delayed Implants in Healed Sockets.
Status: COMPLETED
Conditions: Tooth Extraction|Dental Implantation|Bone Remodeling
Interventions: DEVICE: Extraction and Implant insertion (test)|DEVICE: Implant insertion (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Multi-level School Intervention for LGBTQ Youth
Status: RECRUITING
Conditions: Depression|Anxiety|Post Traumatic Stress Disorder|Coping Behavior|Sexual Minority Stress|Suicidality|Substance Use|Bullying|Harassment
Interventions: BEHAVIORAL: Proud & Empowered
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial Evaluating the Safety and Efficacy of Chemoimmunotherapy Plus Short Course of Mek Inhibitor in First Line of Treatment of Metastatic Non Squamous Non Small Cell Lung Adenocarcinoma With PDL1 < 50 %.
Status: NOT_YET_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Phase I - Mirdametinib - Level 1|DRUG: Phase II - Mirdametinib|DRUG: Phase I - Mirdametinib - Level 2|DRUG: Phase I - Mirdametinib - Level 3|DRUG: Phase I - Mirdametinib - Level 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VIRTUOSE : Efficiency of Sildenafil on the Absolute Claudication Distance of Peripheral Arterial Disease Patients With Intermittent Claudication.
Status: RECRUITING
Conditions: Peripheral Artery Disease
Interventions: DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Surgical Intervention of Congenital Hemivertebra in Young Children
Status: NOT_YET_RECRUITING
Conditions: Congenital Hemivertebra
Interventions: PROCEDURE: posterior hemivertebra resection|PROCEDURE: conservative treatment+ delayed posterior hemivertebra resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Collecting and Storing Tissue and DNA Samples From Patients Undergoing a Donor Stem Cell Transplant
Status: COMPLETED
Conditions: Breast Cancer|Chronic Myeloproliferative Disorders|Gestational Trophoblastic Tumor|Graft Versus Host Disease|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Neuroblastoma|Ovarian Cancer|Testicular Germ Cell Tumor
Interventions: GENETIC: gene expression analysis|GENETIC: microarray analysis|GENETIC: polymorphism analysis|GENETIC: proteomic profiling|OTHER: flow cytometry|OTHER: immunologic technique|OTHER: laboratory biomarker analysis|PROCEDURE: biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prostate Boost Irradiation With Stereotactic Body RT (SBRT)
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: LHRH agonist|RADIATION: Pelvic Radiation|RADIATION: Stereotactic Body Radiotherapy (SBRT)|RADIATION: Conventional Radiotherapy (CRT) Prostate Boost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interventional Treatment of Residual Pulmonary Hypertension in Patients After Pulmonary Thromboendarterectomy
Status: UNKNOWN
Conditions: Chronic Thromboembolic Pulmonary Hypertension
Interventions: PROCEDURE: Radiofrequency pulmonary artery denervation|DEVICE: Ablation catheter|DEVICE: Swan-Ganz catheter for right heart catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Lifitegrast to Treat Dry Eye
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: Lifitegrast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Ascending Dose Study to Assess the Safety and Immunogenicity of Adenovirus Anthrax Vector Candidate Vaccines
Status: COMPLETED
Conditions: Anthrax Infection
Interventions: BIOLOGICAL: AVA|BIOLOGICAL: Ad4-PA-1|BIOLOGICAL: Ad4-PA-GPI-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The SYMPTOMS - SYstematic Elderly Medical Patients Thromboprophylaxis: Efficacy on Symptomatic OutcoMeS - Study
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Enoxaparin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Neuraxial Labor Analgesia and Offspring Neurodevelopment
Status: RECRUITING
Conditions: Offspring, Adult|Labor Pain|Maternal Anesthesia and Analgesia Affecting Fetus or Newborn|Neurodevelopmental Delay|Postpartum Depression
Interventions: PROCEDURE: Neuraxial labor analgesia|PROCEDURE: No neuraxial labor analgesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Investigation of Premama Balance and Its Effects on Hormonal Imbalances
Status: WITHDRAWN
Conditions: PMS|Menstrual Discomfort|Hormone Disturbance|Menstrual Pain|Menstrual Irregularity
Interventions: DIETARY_SUPPLEMENT: PreMama Balance|DIETARY_SUPPLEMENT: Placebo Drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Restore EF Observational Study
Status: COMPLETED
Conditions: Coronary Artery Disease|Unstable Angina|Angina, Stable|NSTEMI - Non-ST Segment Elevation MI
Interventions: DEVICE: Prophylactic Impella support for a non-emergent PCI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Balance, Trunk Impairment and Fear of Falling in Multiple Sclerosis Patients With Incontinence
Status: COMPLETED
Conditions: Multiple Sclerosis|Physical Therapy|Incontinence
Interventions: OTHER: Incontinence Severity|OTHER: Balance|OTHER: Trunk impairment|OTHER: Fear of falling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Proof-of-Concept Trial on Selective Removal of sFlt-1 in Pregnant Women With Preeclampsia Via Apheresis
Status: RECRUITING
Conditions: Preeclampsia
Interventions: DEVICE: TheraSorb sFlt-1 adsorber
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Response to SARS-CoV-2 Vaccine in Stem Cell Transplant and Cellular Therapy Patients
Status: COMPLETED
Conditions: Hematologic Disorders and Bone Marrow Failure, Hematopoietic Stem Cell Transplantation (HSCT) or Cellular Therapy (CART)
Interventions: DIAGNOSTIC_TEST: COVID-19 serology IgG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Silencing Inflammatory Activity by Injecting Nanocort in Patients at Risk for Atherosclerotic Disease
Status: UNKNOWN
Conditions: Atherosclerosis|Inflammation
Interventions: DRUG: liposomal prednisolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Peloidotherapy and Extracorporeal Shock Wave Therapy Efficiency in Patients With Lateral Epicondylitis
Status: UNKNOWN
Conditions: Lateral Epicondylitis
Interventions: DEVICE: Extracorporeal Shock Wave Therapy(ESWT)|OTHER: Peloid therapy|OTHER: Home Workout Program|OTHER: Cold application
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations
Status: RECRUITING
Conditions: GATA2|Immunodeficiency|MDS
Interventions: PROCEDURE: Allogeneic HSCT|DRUG: Busulfan Test dose|DRUG: Fludarabine (Fludara, Berlex Laboratories)|DRUG: Busulfan (Busulfex)|DRUG: Cyclophosphamide (CTX, Cytoxan)|PROCEDURE: Total Body Irradiation (TBI)|DRUG: Mycophenolate mofetil (MMF)|DRUG: Tacrolimus|BIOLOGICAL: Equine Anti-Thymocyte Globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effect of Elbasvir/Grazoprevir Combination Therapy in Hemodialysis Patients With Chronic Hepatitis C
Status: UNKNOWN
Conditions: Chronic Hepatitis C
Interventions: DRUG: elbasvir, grazoprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Humanitarian Device Exemption Post-Approval Study of NeuRx Diaphragm Pacing System for Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: DEVICE: NeuRx Diaphragm Pacing System (DPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Lentil Consumption on Post-prandial Blood Glucose and Insulin
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Various lentil varieties (varying in slow digested starch content)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Cranial Laser Reflex Technique for Hamstring Function
Status: COMPLETED
Conditions: Hamstring Injury|Muscle Tone Increased|Muscle Pain|Muscle Weakness
Interventions: DEVICE: CLRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Three Anti-HIV Drug Combinations in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lamivudine/Zidovudine|DRUG: Abacavir sulfate|DRUG: Nelfinavir mesylate|DRUG: Lamivudine|DRUG: Stavudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm|Acute Myeloid Leukemia Post Cytotoxic Therapy|Acute Myeloid Leukemia, Myelodysplasia-Related
Interventions: DRUG: Azacitidine|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|DRUG: Cytarabine|DRUG: Daunorubicin Hydrochloride|PROCEDURE: Echocardiography|DRUG: Liposome-encapsulated Daunorubicin-Cytarabine|PROCEDURE: Multigated Acquisition Scan|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Designed to Evaluate the Safety of Prophylactic Depakote ER in the Treatment of Adolescents With Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: divalproex sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Evaluation of Hyaluronic Acid Compared to Propylene Glycol as Vehicle for Double Antibiotic Paste in Lesion Sterilization and Tissue Repair Technique for Non-Vital Primary Molars
Status: NOT_YET_RECRUITING
Conditions: Resorption of Tooth or Root
Interventions: DRUG: Hyaluronic acid|DRUG: Propylene glycol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of 0.8% Hyaluronic Acid Gel
Status: COMPLETED
Conditions: Periodontitis
Interventions: DRUG: 0.8% Hyaluronic Acid|PROCEDURE: Scaling and Root Planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tendon Transfer Rotator Cuff Tear
Status: RECRUITING
Conditions: Rotator Cuff Tears
Interventions: PROCEDURE: Lower Trapezius Tendon Transfer Technique|PROCEDURE: Latissimus Dorsi Tendon Transfer Technique|PROCEDURE: Pectoralis Tendon Transfer Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IL-10 Levels and Remote Ischemic Preconditioning in Acute Myocardial Infarction
Status: TERMINATED
Conditions: Acute Myocardial Infarction
Interventions: OTHER: Blood pressure cuff insufflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Evaluate the PK, Safety, Tolerability of BIIB023 in Chinese, Japanese, and Caucasian Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BIIB023 - low dose IV Dose|DRUG: BIIB023 - high dose IV Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigating Safety and Pharmacokinetics of NNC 0128-0000-2011 Compared to NNC 0128-0000-2021 in Healthy Male Subjects
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A|Haemophilia B
Interventions: DRUG: NNC 0128-0000-2011|DRUG: NNC 0128-0000-2021
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Traial to Assess Pharmacokinetic/Pharmacodynamic Profiles and Safety of CKD-843
Status: COMPLETED
Conditions: Alopecia
Interventions: DRUG: CKD-843 A|DRUG: CKD-843 B|DRUG: CKD-843-R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of DNA Mutations in Predicting the Effect of External-Beam Radiation Therapy in Patients With Early Breast Cancer, Localized Prostate Cancer, or Gynecological Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Cervical Cancer|Endometrial Cancer|Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer|Prostate Cancer|Sarcoma|Vaginal Cancer|Vulvar Cancer
Interventions: GENETIC: gene expression analysis|GENETIC: gene rearrangement analysis|GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Ethinylestradiol/Dienogest in Random Start Rapid Endometrial Preparation
Status: COMPLETED
Conditions: Endometrial Polyp|Endometrial Diseases
Interventions: DRUG: Ethinylestradiol/Dienogest 0.03mg/2mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Immunogenicity and Safety of Different Formulations of HBV-MPL Vaccine With Engerix™-B in Adults Aged 19-40 y
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: HBV-MPL vaccine|BIOLOGICAL: Engerix™-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: High-dose Simvastatin for Aneurysmal Subarachnoid Haemorrhage
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage
Interventions: DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Validation of ECG Waveform and Arrhythmia Diagnosis Concordance Using ECG Monitoring Patch and Holter Monitoring
Status: COMPLETED
Conditions: Arrhythmias, Cardiac
Interventions: OTHER: Electrocardiogram measurements by holter device and patch-type electrocardiographic at the same time
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial to Investigate Post Prandial Blood Glucose Control With Fast-acting Human Insulin HinsBet® Compared to Insulin Lispro (Humalog®) and Regular Human Insulin (Huminsulin® Normal) After Ingestion of a Standardized Meal in Subjects With T1DM
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: BioChaperone Human Insulin (HinsBet®)|DRUG: Insulin Lispro (Humalog®)|DRUG: Regular human insulin (Huminsulin® Normal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phaco Versus Small Incision Cataract Surgery (SICS) Health Economic Study
Status: COMPLETED
Conditions: Cataract
Interventions: PROCEDURE: Phacoemulsification cataract extraction surgery|PROCEDURE: Small incision cataract surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test How Taking BI 1015550 for 12 Weeks Affects Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF)
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: BI 1015550|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BCG Vaccination to Protect Healthcare Workers Against COVID-19
Status: COMPLETED
Conditions: Coronavirus Disease 2019 (COVID-19)|Respiratory Illness|Corona Virus Infection|COVID-19
Interventions: DRUG: BCG Vaccine|DRUG: 0.9%NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Bioequivalence Study of Glibenclamide From Glibesyn 5 mg Tablets (Medochemie LTD Cyprus) and Daonil 5 mg Tablets (Sanofi-Aventis Cyprus Ltd. )
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Glibesyn|DRUG: Daonil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Smoking Cessation and Functional CT Assessment
Status: RECRUITING
Conditions: Emphysema
Interventions: DRUG: Sildenafil 20 MG|DRUG: Placebo Oral Tablet|DIAGNOSTIC_TEST: Pulse wave velocity|DIAGNOSTIC_TEST: Carotid artery compliance and stiffness|DIAGNOSTIC_TEST: Pressure wave reflection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Effects of Nutrition on Metabolic Risk Factors and Mechanisms
Status: COMPLETED
Conditions: Obesity|Diet Modification
Interventions: DIETARY_SUPPLEMENT: low carbohydrate food|DIETARY_SUPPLEMENT: standard food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: DUrable Polymer-based STent CHallenge of Promus ElemEnt Versus ReSolute Integrity
Status: UNKNOWN
Conditions: Coronary Artery Disease|Angina Pectoris|Unstable Angina Pectoris|Acute Coronary Syndrome|Coronary Stenosis|Coronary Restenosis
Interventions: DEVICE: Resolute Integrity®|DEVICE: Promus Element®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Combination Therapy Including Anti-PD-1 Immunotherapy in Rectal Cancer With Refractory Distal Metastasis
Status: NOT_YET_RECRUITING
Conditions: Advanced Rectal Cancer|Distal Metastasis
Interventions: COMBINATION_PRODUCT: a combination therapy including tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone for Paediatric Adeno-tonsillectomy - A Dose-finding Study
Status: TERMINATED
Conditions: Postoperative Nausea and Vomiting|Postoperative Pain
Interventions: DRUG: dexamethasone|DRUG: Dexamethasone|DRUG: dexamethasone|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Evolution of Body and Scalp Skin Discomfort in Patients With Hereditary Ichthyosis After Wraps (EnvelopIchtyose)
Status: NOT_YET_RECRUITING
Conditions: Ichthyosis Inherited
Interventions: PROCEDURE: Cutaneous wraps
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Dose Escalation Combination Study in Patients With Chronic Myelogenous Leukemia (CML) and Philadelphia Chromosome-Positive (Ph+) Acute Lymphoblastic Leukemia (ALL)(0457-009)(TERMINATED)
Status: TERMINATED
Conditions: Chronic Myelogenous Leukemia|Leukemia, Lymphoblastic, Acute, Philadelphia-Positive
Interventions: DRUG: MK0457|DRUG: dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Artificial Endometrial Preparation for Frozen Thawed Embryo Transfer Applying Either Endometrin or Utrogestan
Status: SUSPENDED
Conditions: Frozen Thawed Embryo Transfer
Interventions: DRUG: Comparison between two different progesterone administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Cusatuzumab in Combination With Azacitidine Compared With Azacitidine Alone in Patients With Higher-risk Myelodysplastic Syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMML) and Who Are Not Candidates for Hematopoietic Stem Cell Transplantation (HSCT)
Status: WITHDRAWN
Conditions: Myelodysplastic Syndromes|Leukemia, Myelomonocytic, Chronic
Interventions: DRUG: Azacitidine|DRUG: Cusatuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Dose Study Of PF-04620110 In Overweight And Obese, Otherwise Healthy Volunteers
Status: COMPLETED
Conditions: Overweight
Interventions: DRUG: Placebo|DRUG: PF-04620110
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Temporary External Fixation and Open Reduction With Internal Fixation for the Management of Pilon Fracture: A Prospective Clinical Trial.
Status: COMPLETED
Conditions: Pilon Fracture
Interventions: PROCEDURE: Primary open reduction and internal fixation|PROCEDURE: Temporary external fixator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Ataluren in Nonsense Mutation Cystic Fibrosis (ACT CF)
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Ataluren (PTC124®)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of 24 Hour Bronchodilator Efficacy of Tiotropium 18 mcg Delivered Via DISCAIR Versus SPIRIVA 18 µg Delivered Via HANDIHALER® in Patients With Moderate to Severe COPD
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Tiotropium 18 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Gabapentin in Treating Overactive Bladder
Status: COMPLETED
Conditions: Urinary Urgency|Urinary Frequency|Nocturia|Incontinence|Detrusor Uninhibited Activity|Quality of Life
Interventions: DRUG: Gabapentin|DRUG: Solifenacin Succinate|DRUG: Placebo drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Antiresorptive and Bone Forming Material on Dental Implants
Status: UNKNOWN
Conditions: Partial Edentulism
Interventions: DRUG: ALN Gel|DRUG: BMP Gel|DRUG: Mixed Gel|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EEG-based Neurofeedback for Auditory Verbal Hallucinations (HALFEED)
Status: TERMINATED
Conditions: Schizophrenia
Interventions: OTHER: LORETA|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Clinical Study to Assess the Effect of Clopidogrel on the Pharmacokinetics of Selexipag and Its Active Metabolite in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Selexipag|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: AISTCM-Outcome Measurement of Acute Ischemic Stroke With Traditional Chinese Medicine
Status: COMPLETED
Conditions: Cerebral Infarction
Interventions: DRUG: Erigeron breviscapus injection|DRUG: hua tuo zai zao wan (a herbal medicine pill)|DRUG: Compound stroke herbal medicine (8 herbal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Corticosteroid and Lidocain Injections for Tennis Elbow
Status: COMPLETED
Conditions: Tennis Elbow|Lateral Epicondylitis
Interventions: DRUG: Corticosteroid|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A FIH Study to Investigate the Safety, Tolerability and PK of P218
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Oral administration of P218 capsules|DRUG: Oral administration of P218 matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SmartCPR Trial: An Analysis of a Waveform-Based Automated External Defibrillation (AED) Algorithm on Survival From Out-of-Hospital Ventricular Fibrillation
Status: COMPLETED
Conditions: Ventricular Fibrillation|Cardiac Arrest
Interventions: DEVICE: Automated external defibrillator (Philips FR2+ AED)|DEVICE: SmartCPR|OTHER: Delayed defibrillation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Epirubicin and Docetaxel Combination (ET) or Epirubicin Followed by Docetaxel (E/T) for Node Negative (N0) High Risk Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: Epirubicin|DRUG: Epirubicin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Palmaz Mach-5 Grooved Bare Metal Coronary Stent System Versus the Palmaz Bare Metal Coronary Stent System in Patients With Symptomatic Ischemic Heart Disease: A Safety and Performance Study
Status: COMPLETED
Conditions: Ischemic Heart Disease
Interventions: DEVICE: coronary stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leflunomide EfficAcy Response Related to Dosing Regimen in Early Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: leflunomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phone Interview to Prevent Recurring Opioid Overdoses
Status: COMPLETED
Conditions: Overdose|Opioid-related Disorders|Drug Addiction|Drug Abuse|Substance Abuse|Opioid Use, Unspecified|Opioid Dependence|Drug Overdose
Interventions: BEHAVIORAL: TTIP-PRO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Red Cell Distribution Width Index Versus Red Cell Distribution Width as Discriminating Guide for Iron Deficiency Anaemia and Beta Thalassemia Trait .
Status: UNKNOWN
Conditions: Microcytic Hypochromic Anemia
Interventions: OTHER: CBC , Iron study and Haemoglobin electrophoresis .
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Novel Topical Therapies for the Treatment of Genital Pain
Status: COMPLETED
Conditions: Female Genital Diseases
Interventions: DRUG: Amitriptyline|DRUG: Baclofen|DRUG: Ketoprofen|DRUG: Ketamine|DRUG: Loperamide|DRUG: Gabapentin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Skin Glue to Reduce Intravenous Catheter Failure in Children
Status: COMPLETED
Conditions: Dislodged Catheter
Interventions: DEVICE: Cyanoacrylate glue|OTHER: Transparent polyurethane dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Children and Teens in Charge of Their Health
Status: UNKNOWN
Conditions: Spina Bifida|Cerebral Palsy|Health Behavior
Interventions: BEHAVIORAL: Solution-Focused Coaching in Pediatric Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Azacitidine in Treating Patients With Relapsed Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia Who Have Undergone Stem Cell Transplant
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Childhood Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Myeloid Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Secondary Myelodysplastic Syndromes
Interventions: DRUG: azacitidine|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 14473 - D9126C00001 Proof of Principle Study - Effect of AZD2066 on Transient Lower Esophageal Sphincter Relaxations
Status: COMPLETED
Conditions: Reflux Episodes
Interventions: DRUG: AZD2066|DRUG: Placebo|DRUG: AZD2066|DRUG: AZD2066|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Developing a Home Telehealth Program to Manage Pressure Ulcers in SCI/D
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: BEHAVIORAL: Daily telephone calls|BEHAVIORAL: Weekly telephone calls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of the Efficacy of Carnipure® AAS on Body Composition, Muscle Thickness, and Strength Adaptations in Healthy Men
Status: RECRUITING
Conditions: Muscle Hypotrophy
Interventions: DIETARY_SUPPLEMENT: Carnipure AAS|DIETARY_SUPPLEMENT: Creatine Monohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Attenuation of Hemodynamic Response to Laryngoscopy and Endotracheal Intubation With Single Dose of Dexmedetomidine in Hypertensive Patients.
Status: COMPLETED
Conditions: Stress Response During Laryngoscopy Intubation
Interventions: DRUG: Dexmedetomidine|DRUG: sterile saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Evaluation of Laparoendoscopic Single Site Versus Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Gallbladder Disease
Interventions: PROCEDURE: LESS cholecystectomy|PROCEDURE: Laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Efficacy and Safety of MC0518 Versus Best Available Therapy in Participants With Steroid-Refractory Acute Graft Versus Host Disease
Status: RECRUITING
Conditions: Steroid-refractory Acute Graft-versus-host Disease
Interventions: BIOLOGICAL: MC0518|BIOLOGICAL: BAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ulcerative Colitis Study: Study of Visilizumab in Patients With Severe Ulcerative Colitis
Status: COMPLETED
Conditions: Severe Ulcerative Colitis
Interventions: DRUG: Visilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnosis and Monitoring of Eosinophilic Esophagitis Using the Cytosponge
Status: TERMINATED
Conditions: Eosinophilic Esophagitis|EoE
Interventions: DEVICE: Cytosponge™ Cell Collection Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Internet-based System for Cancer Patients to Self-report Toxicity
Status: COMPLETED
Conditions: Cervical Cancer|Lung Cancer|Prostate Cancer|Vaginal Cancer|Ovarian Cancer|Breast Cancer|Bladder Cancer
Interventions: BEHAVIORAL: Questioners|BEHAVIORAL: STAR website
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Comparative Safety and Efficacy Evaluation Between Dermacyd Silver and Glycerine Vegetal Soap Granado Traditional
Status: COMPLETED
Conditions: Hygiene
Interventions: DRUG: Dermacid Silver (Lactic acid)|DRUG: Glycerine Vegetal Soap Granado Traditional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT