pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Immediate Versus Postponed Single Blastocyst Transfer in Programmed or Stimulated Cycle Frozen Embryo Transfer
Status: RECRUITING
Conditions: Infertility|IVF
Interventions: PROCEDURE: Immediate FET in a stimulated or programmed cycle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In-Home Evaluation of Episodic Administration of Palovarotene in Fibrodysplasia Ossificans Progressiva (FOP) Subjects
Status: TERMINATED
Conditions: Fibrodysplasia Ossificans Progressiva
Interventions: DRUG: Palovarotene
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intracervical Anasthesia in Outpatient Hystroscopy, Can Procedure be Completed Diagnostic and Therapeutic With no Need to General Anaesthesia
Status: COMPLETED
Conditions: Infertility, Female
Interventions: PROCEDURE: study group|PROCEDURE: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating the Safety and Efficacy of Tradipitant vs. Placebo in Idiopathic and Diabetic Gastroparesis
Status: RECRUITING
Conditions: Idiopathic Gastroparesis|Diabetic Gastroparesis|Gastroparesis
Interventions: DRUG: Tradipitant|DRUG: Placebo|DRUG: Open Label Tradipitant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cold Urticaria Treatment With Xolair
Status: COMPLETED
Conditions: Cold Contact Urticaria
Interventions: DRUG: Omalizumab|DRUG: Omalizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine With or Without Azithromycin for Virologic Cure of COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Hydroxychloroquine|DRUG: Azithromycin|OTHER: Placebo Tablet|OTHER: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VKORC1 and CYP2C9 Gene Polymorphisms and Warfarin Management
Status: UNKNOWN
Conditions: Atrial Fibrillation|Cardiac Thrombus|Deep Vein Thrombosis|Pulmonary Embolism|Heart Valve Replacement (Mechanical or Biological With AF)|Cardiomyopathy (Ischemic or Dilated)|Peripheral Vascular Disease
Interventions: DRUG: Warfarin dose titration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Locally Optimised Contouring With AI Technology for Radiotherapy
Status: NOT_YET_RECRUITING
Conditions: Contouring|Segmentation|Radiation Therapy|Artificial Intelligence|Deep Learning
Interventions: DEVICE: AI assisted contouring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Long-Term Administration of Human Albumin in Subjects With Decompensated Cirrhosis and Ascites
Status: COMPLETED
Conditions: Decompensated Cirrhosis and Ascites
Interventions: DRUG: Albutein 20% Injectable Solution|OTHER: Standard medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATG Combined With Cyclophosphamide And Cord Blood Transfusion in Treating Patients With Severe Aplastic Anemia
Status: UNKNOWN
Conditions: Aplastic Anemia
Interventions: DRUG: Rabbit ATG, (Genzyme)|DRUG: Cy|DRUG: CsA|BIOLOGICAL: Cord blood
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening Contrast-Enhanced Mammography as an Alternative to MRI
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DEVICE: Contrast-enhanced mammography|DRUG: Iodinated Contrast Media (ICM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate the Combination of Platinum-pemetrexed Based Chemotherapy Plus Lorlatinib in ALK Positive Non-Small Cell Lung Cancer (NSCLC) With Exclusively Extracranial Disease Progression on Lorlatinib
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer Metastatic|ALK Gene Mutation
Interventions: DRUG: Lorlatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Low Carbohydrate, Non-Ketogenic Diet Versus Standard Diabetes Diet on Glycemic Control in Type 1 Diabetes
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 1
Interventions: OTHER: Low carbohydrate diet|OTHER: Standard of care diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coronary MDCTA With Iopamidol Injection 370
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Isovue 370, 70 mL|DRUG: Isovue 370, 80 mL|DRUG: Isovue 370, 90 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Acute Heart Failure - COngestion Discharge Evaluation
Status: RECRUITING
Conditions: Acute Heart Failure
Interventions: PROCEDURE: Clinical examination centered on congestion|PROCEDURE: Cardiac, pulmonary, peritoneal, jugular, renal Doppler ultrasounds and liver elastography|PROCEDURE: Blood sample retrieved for biological assessment and biobanking|PROCEDURE: Telephone follow-up|BEHAVIORAL: Kansas City Cardiomyopathy Questionnaire (KCCQ)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trospium Chloride vs Tamsulosin in Treatment of Ureteral Stent Related Symptoms:
Status: SUSPENDED
Conditions: Ureter Stone|Quality of Life|Ureter Obstruction
Interventions: DRUG: Trospium Chloride|DRUG: Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Postoperative Pain and Quality of Life After Taking a Deephethelized Gingival Graft and Covering it With Different Treatments
Status: RECRUITING
Conditions: Pain, Postoperative|Quality of Life|Palate; Wound
Interventions: DEVICE: Deepithelized graft and protection technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Assessment of Iron Sucrose (Venofer) in Patients With Chronic Kidney Disease Who Cannot Tolerate Ferumoxytol (Feraheme) or Iron Dextran (INFed or Dexferrum)
Status: WITHDRAWN
Conditions: Iron Deficiency Anemia
Interventions: DRUG: Iron Sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nadroparin for the Initial Treatment of Pulmonary Thromboembolism
Status: COMPLETED
Conditions: Pulmonary Embolism|Thromboembolism|Vascular Diseases|Thrombosis
Interventions: DRUG: Nadroparin|DRUG: Unfractionated heparin(UFH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 28-Day Parallel Group Study of TD-4208 in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: TD-4208|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interleukin-21 (IL-21)- Expanded Natural Killer Cells for Induction of Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: NK Cells + Chemotherapy Starting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomised Clinical Trial Assessing the Efficacy and Safety of Mycophenolate Mofetil Versus Azathioprine for Induction of Remission in Treatment Primary Biliary Cholangitis-Autoimmune Hepatitis Overlap Syndrome
Status: UNKNOWN
Conditions: Autoimmune Hepatitis|Primary Biliary Cirrhosis
Interventions: DRUG: Methylprednisolone and Mycophenolate mofetil|DRUG: Methylprednisolone and azathioprine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Randomized Clinical Trial to Evaluate the Effects of Intermittent Caloric Restriction in Patients With Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia.
Status: WITHDRAWN
Conditions: Prostatic Hyperplasia, Benign|Metabolic Syndrome
Interventions: BEHAVIORAL: Caloric Restriction|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GANNET53: Ganetespib in Metastatic, p53-mutant, Platinum-resistant Ovarian Cancer
Status: TERMINATED
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: DRUG: Ganetespib|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic Mini Gastric Bypass
Status: UNKNOWN
Conditions: Obesity|Bypass Complications
Interventions: PROCEDURE: Mini Gastric Bypass|PROCEDURE: Roux-en-Y Gastric Bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Addition of Pre-wound Closure Povidone Iodine Wash Versus Direct Wound Closure Effect on Surgical Site Infections
Status: UNKNOWN
Conditions: Surgical Site Infection|Surgical Wound Infection
Interventions: DRUG: 10% Povidone Iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Education, Counseling, and Drug Therapy to Reduce Symptoms of Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome X|Prediabetic State|Insulin Resistance|Obesity|Metabolic Diseases
Interventions: DRUG: Dietary supplement for weight loss|BEHAVIORAL: Education and counseling for weight loss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Italian Randomized Open-label Study of Occipital Nerve Stimulation in the Treatment of Chronic Migraine Headache
Status: COMPLETED
Conditions: Headache, Migraine
Interventions: DEVICE: Occipital nerve stimulation ON|DEVICE: Occipital nerve stimulation off
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Solid Tumors, Adult|Endometrial Cancer|Pancreatic Cancer|Cervical Cancer|Breast Cancer|Carcinoma of Unknown Primary
Interventions: DRUG: TNG260|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accuracy Evaluation of Different "All on Four" Impression Techniques Using Plaster Jig
Status: ACTIVE_NOT_RECRUITING
Conditions: Implant Prosthodontics
Interventions: PROCEDURE: Impression techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Intermittent Oral Dosing of ASP1517 in Hemodialysis Chronic Kidney Disease Patients With Anemia
Status: COMPLETED
Conditions: Hemodialysis Chronic Kidney Disease Patients With Anemia
Interventions: DRUG: roxadustat|DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Approaches to Target MECOM/EVI1 in AML
Status: RECRUITING
Conditions: AML, Adult
Interventions: BIOLOGICAL: Biological characterization of AML with MECOM or atypical 3q26 rearrangements
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Single-Centre Study of VR040(Inhaled Apomorphine) in Idiopathic Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Inhaled VR040|DRUG: Placebo for VR040
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-Ranging Study to Determine the Efficacy, Safety and Tolerability of AeroFact
Status: COMPLETED
Conditions: Respiratory Distress Syndrome in Premature Infant
Interventions: DRUG: AeroFact|OTHER: nCPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pigeon Peas (Cajanus Cajan) : a Natural Anti-inflammatory Facilitating Weight Loss in Obese Patients Returning to Sport?
Status: NOT_YET_RECRUITING
Conditions: Severe Obesity
Interventions: BIOLOGICAL: Standardized physical activity protocol associated with the consumption of Cajanus cajan (EXACAJAN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Milk Proteins on Satiety, Food Intake and Metabolic Control (Glycemia) in Early Adulthood
Status: COMPLETED
Conditions: Hyperglycemia|Lack of Satiety
Interventions: OTHER: Skim milk products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability and Pharmacodynamic Effect of Fazirsiran (TAK-999, ARO-AAT)
Status: COMPLETED
Conditions: Alpha 1-Antitrypsin Deficiency
Interventions: DRUG: Fazisiran Injection|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ocular Tolerance, Safety and Ocular Pharmacokinetics After 1 Drop of T1225 0.5, 1.0, 1.5% in 48 Healthy Volunteers
Status: COMPLETED
Conditions: Eye Infections, Bacterial
Interventions: DRUG: Azithromycin (T1225)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Shockwave Therapy for the Treatment of Chronic Angina Pectoris
Status: SUSPENDED
Conditions: Refractory Angina Pectoris
Interventions: DEVICE: Cardiac Extracorporeal Shockwave Therapy generator (Cardiospec)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study Using Zone-MPC Controller, HMS and Technosphere® Insulin Inhalation System From MannnKind Corp
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Investigational inhaled insulin (Technosphere)|DEVICE: Artificial Pancreas (AP) device (APS©)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Loop Ileostomy Closure:Stapled or Hand-sewn Anastomoses? Suture or Mesh Closure of the Stoma Site?
Status: RECRUITING
Conditions: Rectal Neoplasm
Interventions: PROCEDURE: Stapled or Hand-sewn anastomosis|PROCEDURE: Mesh or suture stoma site closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: PROTECT-1: A Study of the Selective A1 Adenosine Receptor Antagonist KW-3902 for Patients Hospitalized With Acute HF and Volume Overload to Assess Treatment Effect on Congestion and Renal Function
Status: COMPLETED
Conditions: Heart Failure, Congestive
Interventions: DRUG: rolofylline|DRUG: Comparator: Placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Trial On RadiaTion Dose Estimates Of CT AngIOgraphy In PatieNts Scanned With A Sequential Scan Protocol
Status: UNKNOWN
Conditions: Coronary Disease
Interventions: RADIATION: Spiral image acquisition|RADIATION: sequential image acquisition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Rituximab With or Without Yttrium Y-90 Ibritumomab Tiuxetan in Treating Patients With Untreated Follicular Lymphoma
Status: COMPLETED
Conditions: Ann Arbor Stage I Grade 1 Follicular Lymphoma|Ann Arbor Stage I Grade 2 Follicular Lymphoma|Ann Arbor Stage II Grade 1 Contiguous Follicular Lymphoma|Ann Arbor Stage II Grade 1 Non-Contiguous Follicular Lymphoma|Ann Arbor Stage II Grade 2 Contiguous Follicular Lymphoma|Ann Arbor Stage II Grade 2 Non-Contiguous Follicular Lymphoma|Ann Arbor Stage III Grade 1 Follicular Lymphoma|Ann Arbor Stage III Grade 2 Follicular Lymphoma|Ann Arbor Stage IV Grade 1 Follicular Lymphoma|Ann Arbor Stage IV Grade 2 Follicular Lymphoma
Interventions: OTHER: Quality-of-Life Assessment|BIOLOGICAL: Rituximab|RADIATION: Yttrium Y-90 Ibritumomab Tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Intensity Total Body Irradiation + Thymoglobulin Followed by Allogeneic PBSCT
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Leukemia|Multiple Myeloma|Acute Myeloid Leukemia|Hodgkin Lymphoma|Chronic Lymphocytic Leukemia|Chronic Myelogenous Leukemia|Myelodysplastic Syndrome
Interventions: BIOLOGICAL: Thymoglobulin|RADIATION: Total-Body Irradiation|PROCEDURE: Allogeneic PBSCT or BMT|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Fenugreek Seed Extract, a Nutraceutical in Patients With Type- 2 Diabetes
Status: COMPLETED
Conditions: Type-2 Diabetes Mellitus
Interventions: DRUG: Oral hypoglycemic agents (pre-specified) [Metformin, Sulfonylurea]|DIETARY_SUPPLEMENT: Fenugreek Seed extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Study of Rituximab (SC) Administered in Participants With CD20+ DLBCL or CD20+ Follicular NHL Grade 1 to 3A
Status: COMPLETED
Conditions: Non-Hodgkin Lymphoma
Interventions: DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Obatoclax Mesylate (GX15-070MS) in the Treatment of Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Hodgkin's Lymphoma
Interventions: DRUG: Obatoclax mesylate (GX15-070MS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Of Sensory Training and Electrical Stimulation on Sole of The Foot Sensations in Patients With Acute Hemiplegia
Status: COMPLETED
Conditions: Hemiplegia|Stroke, Acute|Sensory Disorders
Interventions: OTHER: Sensory training|OTHER: Electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Two Iron Preparations on Protein in the Urine
Status: COMPLETED
Conditions: Kidney Failure, Chronic|Anemia, Iron-Deficiency
Interventions: DRUG: Sodium Ferric Gluconate and Iron sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Acupoint Stimulation for Non-small Cell Lung Cancer Patients
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer|Lung Cancer
Interventions: DEVICE: TEAS|DRUG: Sanguisorba officinalis L.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Sky Automatic Technologies in Pediatrics
Status: NOT_YET_RECRUITING
Conditions: Hearing Loss
Interventions: DEVICE: Cochlear implant processor Sky CITM M90 (CI-5295)|DEVICE: Hearing Aid, including sound processor Phonak: Sky Link M90|DIAGNOSTIC_TEST: French simplified matrix test (FraSimat)|BEHAVIORAL: Audiologist Fitting Questionnaire|BEHAVIORAL: Patient Satisfaction Questionnaire|BEHAVIORAL: AutoSens Feedback Discussion Form
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Two Doses of Multimeric-001 (M-001) Followed by Influenza Vaccine
Status: COMPLETED
Conditions: Influenza|Influenza Immunisation
Interventions: BIOLOGICAL: Influenza Multimeric-001 Vaccine|OTHER: Placebo|BIOLOGICAL: Quadrivalent Recombinant Seasonal Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PF-00489791 For The Treatment Of Raynaud's
Status: COMPLETED
Conditions: Raynaud's Disease|Peripheral Vascular Disease
Interventions: DRUG: PF-00489791|DRUG: PF-00489791|DRUG: PF-00489791|DRUG: PF-00489791|DRUG: PF-00489791|DRUG: PF-00489791|DRUG: PF-00489791|DRUG: PF-00489791
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Single Agent CJM112, and PDR001 in Combination With LCL161 or CJM112 in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: PDR001|DRUG: CJM112|DRUG: LCL161
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Canagliflozin on Liver Inflammation Damage in Type 2 Diabetes Patients With Nonalcoholic Fatty Liver Disease
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus With Complication
Interventions: DRUG: Canagliflozin|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Role of Doppler Ultrasound in Assessment of Local Factors Affecting Maturation of Arteriovenous Fistula in Hemodialysis Patient
Status: UNKNOWN
Conditions: Doppler Ultrasound in Arteriovenous Fistula Preoperative Evaluation and Post-operative Periodic Monitoring
Interventions: DIAGNOSTIC_TEST: doppler ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 1 Study of Zoledronic Acid in Sickle Cell Disease
Status: WITHDRAWN
Conditions: Sickle Cell Disease
Interventions: DRUG: Placebo|DRUG: Zoledronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Full-dose Atorvastatin After Acute Coronary Syndrome (ACS) in Non-revascularisable Coronary Artery Disease
Status: TERMINATED
Conditions: Acute Coronary Syndrome|Coronary Artery Disease
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Repeat Doses of IV Serelaxin in Subjects With Chronic Heart Failure
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: DRUG: RLX030 (serelaxin)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Improving Dynamic Balance and Gait Adaptability Using Treadmill Training
Status: UNKNOWN
Conditions: Multiple Sclerosis|Stroke|Parkinson Disease
Interventions: DEVICE: Virtual Reality Treadmill Training|DEVICE: Treadmill training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Design Thinking Methodology to Engage Hispanic and Latino Families of Autistic Children in Research.
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder|Patient Engagement
Interventions: OTHER: Design Thinking|OTHER: Focus Groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effects of Gentle Movements at the Ankle in Individuals With Diminished Range of Motion
Status: UNKNOWN
Conditions: Lateral Ankle Sprain
Interventions: OTHER: Sham ("laying of hands") intervention|OTHER: Grade IV AP joint mobilizations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alveolar Ridge Preservation With Putty Allograft vs. Putty Alloplast Graft
Status: RECRUITING
Conditions: Alveolar Bone Resorption
Interventions: BIOLOGICAL: demineralized and mineralized combination putty bone allograft|BIOLOGICAL: calcium phosphosilicate putty alloplast graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sensor-augmented Pump Versus Multiple Daily Injections With Degludec as Basal Insulin for Insulin Therapy in Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: CGM+CSII|DEVICE: MDI with degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Nadifloxacin Cream Alone and With Benzoyl Peroxide Solution in the Treatment of Acne
Status: UNKNOWN
Conditions: Acne Vulgaris
Interventions: DRUG: benzoyl peroxide|DRUG: nadifloxacine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: I-gel vs Ambu AuraGain in Laparoscopic Gynecological Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Airway Morbidity|Anesthesia
Interventions: DEVICE: i-gel|DEVICE: Ambu AuroGain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of [18]F-FDG on PET/CT as an Alternative Non-invasive Method for Staging of Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Carcinoma
Interventions: OTHER: Use of [18f]FDG - PET/CT for the diagnosis and staging of non-small cell lung carcinoma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Drug Sensitivity Detection of Micro Tumor (PTC) to Guide Postoperative Adjuvant Treatment Strategy of Colorectal Cancer
Status: RECRUITING
Conditions: Colon Cancer|Rectal Cancer|Chemotherapy Effect|PTC|Exon Mutation
Interventions: DRUG: 5-fluorouracil + formyltetrahydrofolate/Oxaliplatin + 5-fluorouracil + formyltetrahydrofolate/Irinotecan + 5-fluorouracil + formyltetrahydrofolate/Cetuximab + 5-fluorouracil + formyltetrahydrofolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pre-op Cognitive Behavior Therapy to Decrease Chronic Post-Surgical Pain in TKA
Status: COMPLETED
Conditions: Chronic Post-Surgical Pain
Interventions: BEHAVIORAL: Computer-Assisted Preoperative CBT Intervention (PAINTrainer)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Use in SZMN Blocks for Pediatric T&A Pain Control
Status: RECRUITING
Conditions: Postoperative Pain|Opioid Use
Interventions: PROCEDURE: SZMN block|PROCEDURE: SZMN block with Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Lesion Load and Location in Relation to Cognition, Fatigue and Physical Disability in RRMS
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DIAGNOSTIC_TEST: VolBrain, a fully automated platform to generate the volumetric data (lesion count, volume and location as well as different atrophy measures)|OTHER: Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the EFFECTS of Acetylsalicylic Acid (ASA) on Niaspan®-Induced Flushing in Subjects With Dyslipidemia
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: niacin extended-release (NER)|DRUG: aspirin (ASA)|DRUG: aspirin placebo (ASA Pbo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Fermented Prunus Mume Vinegar on Improvement of Fatigue
Status: COMPLETED
Conditions: Fatigue
Interventions: DIETARY_SUPPLEMENT: Fermented Prunus Mume Vinegar group|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise for Healthy Aging: The Impact of HIV and Aging on Physical Function and the Somatopause
Status: COMPLETED
Conditions: HIV|Inflammation|Obesity|Aging, Biological
Interventions: OTHER: High-intensity cardiovascular and resistance exercise|OTHER: Moderate-intensity cardiovascular and resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety Trial of ALK-depot SQ Mites in Subjects With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: subcutaneous immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Toric Orthokeratology - Slowing Eye Elongation
Status: COMPLETED
Conditions: Myopia|Astigmatism
Interventions: DEVICE: Toric Orthokeratology lenses|DEVICE: Single-vision spectacles
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Implantation in Posterior Maxilla in Cases With Insufficient Bone
Status: COMPLETED
Conditions: Bone Loss in Jaw|Implant Site Reaction
Interventions: PROCEDURE: Tilted insertion of implants|PROCEDURE: Straight insertion of implants
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Lenvatinib w/ Pembro in Black Participants w/Mismatch Repair-Prof Recurrent Endometrial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Cancer|Mismatch Repair-Proficient|Recurrent Endometrial Cancer
Interventions: DRUG: Lenvatinib|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Propranolol Hydrochloride in Treating Patients With Locally Recurrent or Metastatic Solid Tumors That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Male Breast Cancer|Recurrent Melanoma|Stage IV Breast Cancer|Stage IV Melanoma|Stage IV Ovarian Epithelial Cancer|Stage IV Ovarian Germ Cell Tumor|Unspecified Adult Solid Tumor, Protocol Specific|Hepatocellular Carcinoma
Interventions: DRUG: propranolol hydrochloride|OTHER: Correlative Studies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate PF-06730512 in Adults With Focal Segmental Glomerulosclerosis (FSGS)
Status: TERMINATED
Conditions: Focal Segmental Glomerulosclerosis (FSGS)
Interventions: DRUG: PF-06730512
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Modified Xiao-Feng Powder for Chronic Urticaria
Status: UNKNOWN
Conditions: Chronic Urticaria
Interventions: DRUG: Modified Xiao-Feng Powder + Antiallergics|OTHER: Placebo + Antiallergics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conventionally Fractionated Adaptive Radiation Therapy of Bladder Cancer an Individualized Approach
Status: RECRUITING
Conditions: Muscle-Invasive Bladder Carcinoma
Interventions: DEVICE: Varian Ethos Adaptive Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dosage Schedule Study of Pemetrexed Monochemotherapy for Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Pemetrexed - Before Protocol Amendment|DRUG: Pemetrexed - After Protocol Amendment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Cyclophosphamide and Abatacept With Standard of Care Treatment Following Stem Cell Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: GVHD|Hematologic Neoplasms
Interventions: DRUG: Cyclophosphamide|DRUG: abatacept|DRUG: Methotrexate|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation Effect on Vulvovaginal Atrophy in Postmenopausal Women.
Status: WITHDRAWN
Conditions: Vulvovaginal Atrophy
Interventions: DRUG: Estrogen vaginal cream group (group A)|RADIATION: Photobiomodutation group (group B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pain, Anxiety and Complications Related to Cannulation of Arteriovenous (AV) Fistula in Chronic Hemodialysis Patients
Status: COMPLETED
Conditions: Dialysis|Fistula
Interventions: DEVICE: catheter for AV fistula cannulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritive Effects of a Cow's Milk Based Formula Fed to Young Children
Status: COMPLETED
Conditions: Child Nutrition Sciences
Interventions: OTHER: Cow's milk-based formula with added nutrients|OTHER: Cow's milk-based formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Effect of a Pre-Clinical Practice Simulation Using Virtual Reality Stress and Anxiety Levels
Status: ENROLLING_BY_INVITATION
Conditions: Clinical Practice|Virtual Reality|Nursing Education|Nursing Students|Simulation
Interventions: OTHER: Virtual Reality Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Brain Activity During Bladder Filling: Pilot Study of an fMRI Protocol
Status: NOT_YET_RECRUITING
Conditions: fMRI Research
Interventions: DIAGNOSTIC_TEST: invasive urodynamic evaluation|DIAGNOSTIC_TEST: functional magnetic resonance imaging during bladder filling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Efficacy and Safety Study of Neoadjuvant in Treating Patients With Resectable Local Recurrent Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: PROCEDURE: surgical resection and adjuvant therapy|PROCEDURE: Neoadjuvant followed by operation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Carboplatin-Paclitaxel/Nab-Paclitaxel Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With First Line Metastatic Squamous Non-small Cell Lung Cancer (MK-3475-407/KEYNOTE-407)-China Extension Study
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Paclitaxel|DRUG: Nab-paclitaxel|DRUG: Carboplatin|DRUG: Saline placebo for pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of the Second Generation of the Controlled Attenuation Parameter (CAP) Using the MRI-PDFF as Reference
Status: COMPLETED
Conditions: Chronic Liver Disease
Interventions: DEVICE: FibroScan 530 Compact
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Tranexamic Acid (TXA) on Reduction of Postoperative Blood Transfusion
Status: UNKNOWN
Conditions: Hip Fractures
Interventions: DRUG: Tranexamic Acid (TXA)|DRUG: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pillars4Life Trial
Status: COMPLETED
Conditions: Breast Cancer|Lung Cancer|Esophageal Cancer|Colon Cancer|Pancreatic Cancer|Liver Cancer|Renal Cancer|Bladder Cancer|Prostate Cancer|Ovarian Cancer|Cervical Cancer|Uterine Cancer
Interventions: BEHAVIORAL: Pillars4Life
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Post-Marketing Surveillance of TISSUCOL for Hemostasis in Subjects Undergoing Vascular Reconstruction With Polytetrafluoroethylene (PTFE) Prosthesis
Status: COMPLETED
Conditions: Femoral Vascular Anastomosis
Interventions: DRUG: Tissucol®|PROCEDURE: Control: Conventional treatment, i.e. compression with swabs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Minocycline for Alcohol Use Disorder
Status: WITHDRAWN
Conditions: Alcohol Use Disorder|Inflammation|Neurocognitive Dysfunction|Craving|Alcohol Drinking
Interventions: DRUG: Minocycline|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Setting ERCP and Laparoscopic Cholecystectomy is a Safe Procedure in Patients With Cholecysto-Choledocholithiasis
Status: COMPLETED
Conditions: Choledocholithiasis With Cholecystitis With Obstruction|Choledocholithiasis With Acute and Chronic Cholecystitis|Cholelithiasis With Acute and Chronic Cholecystitis
Interventions: PROCEDURE: ERCP+LC|PROCEDURE: OC+CBD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical, Functional and Inflammatory Evaluation in Asthmatic Patients After a Simple Short-Term Educational Program
Status: COMPLETED
Conditions: Asthma|Inflammation|Patient Relations, Nurse|Spirometry
Interventions: BEHAVIORAL: Individualized educational program|DIAGNOSTIC_TEST: Induced sputum collection|DIAGNOSTIC_TEST: Spirometry|DIAGNOSTIC_TEST: Nitric oxide measure|OTHER: Questionnaires ACT, ACQ, AQLQ, BDI|OTHER: Symptoms Diary|DIAGNOSTIC_TEST: Peak flow measure|DIAGNOSTIC_TEST: Exhaled breath condensate air measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mesenchymal Stem Cell Therapy for the Treatment of Severe or Refractory Inflammatory and/or Autoimmune Disorders
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: Mesenchymal Stem Cells (MSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Legalon SIL for the Treatment of HCV Recurrence in Liver Transplanted Patients
Status: TERMINATED
Conditions: HCV Recurrence After Liver Transplantation
Interventions: DRUG: Silibinin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Stereotactic Radiotherapy With Anlotinib in Patients With Recurrent High-Grade Gliomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Glioma
Interventions: RADIATION: Hypofractionated Stereotactic Radiotherapy|DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of YM155 Plus Rituximab in Subjects With Non-Hodgkin's Lymphoma Who Have Received Prior Treatment
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: YM155|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Down Sizing Strategy (HANGZHOU Solution) vs Standard Sizing Strategy TAVR in Bicuspid Aortic Stenosis (Type 0)
Status: RECRUITING
Conditions: Aortic Stenosis With Bicuspid Valve
Interventions: PROCEDURE: TAVR for BAV Using Down Sizing with the Evolut Pro platform|PROCEDURE: TAVR for BAV Using Traditional Sizing strategy with the Evolut Pro platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Versus Early (24-hours) Urinary Catheter Removal After Elective Minimally Invasive Colonic Resection
Status: RECRUITING
Conditions: Surgical Complication|Colonic Disease|Postoperative Complications|Urinary Retention Postoperative|Urinary Tract Infections
Interventions: DEVICE: Immediate urinary catheter removal|DEVICE: Early urinary catheter removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Adaptive Phase II Study to Evaluate the Safety & Efficacy of NaBen®
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: NaBen®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of APA on Sleep Quality in Children With Cancer From 5 to 16 Years
Status: NOT_YET_RECRUITING
Conditions: Child, Only|Blood Cancer|Adapted Physical Activity|Sleep
Interventions: BEHAVIORAL: practice adapted physical activity|OTHER: control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Docetaxel, Doxorubicin (A), Cyclophosphamide (C) (TAC) vs 5-Fluorouracil, A, C (5FAC) Breast Cancer Adjuvant Treatment
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Docetaxel|DRUG: 5-fluorouracil|DRUG: Doxorubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study to Evaluate SNDX- 6352 in Participants With Active cGVHD
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Graft-versus-host-disease
Interventions: DRUG: SNDX-6352
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ejaculatory Abstinence in IUI Cycles
Status: COMPLETED
Conditions: Infertility|Spermatozoa|Reproductive Disorder
Interventions: PROCEDURE: INTRAUTERINE INSEMINATION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Hydration Dynamics and Influence of Beverage Composition
Status: COMPLETED
Conditions: Hydration|Fluid Retention|Dehydration
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: Oral Rehydration Solution 1|BIOLOGICAL: Oral Rehydration Solution 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Clopidogrel and Ticagrelor With and Without Acetylsalicylic Acid (ASA) on Hemostatic System Activation at the Site of Plug Formation in Vivo in Man
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Clopidogrel|DRUG: Ticagrelor|DRUG: ASA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MATCH: The Mexican-American Trial of Community Health Workers
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Community Health Worker Intervention|BEHAVIORAL: Educational Newsletter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Excitatory Prefrontal Weak Current Stimulation in Vegetative Patients
Status: COMPLETED
Conditions: Disorder of Consciousness|MMN|Modification of Cognitive Status Indication|Anoxic Brain Damage|Trauma, Brain|Vegetative State|EEG; Paroxysms, Occipital, Epilepsy of Childhood|Cortical Atrophy
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT