pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Exercise to Enhance Cardiovascular Health Among Black Prostate Cancer Patients With Androgen Deprivation Therapy
Status: RECRUITING
Conditions: Androgen Deprivation Therapy|Prostate Cancer|Prostate Cancer Metastatic
Interventions: OTHER: Aerobic and resistance exercise|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Bevacizumab in Combination With Gemcitabine and Carboplatin in Participants With Triple Negative Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Bevacizumab|DRUG: Carboplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ranolazine in Patients With Chronic Total Occlusions of Coronary Arteries
Status: WITHDRAWN
Conditions: Myocardial Ischemia|Coronary Artery Disease|Arteriosclerosis|Chronic Stable Angina
Interventions: DRUG: Ranolazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transversalis Fascia Plane Block Versus Erector Spinae Plane Block for Analgesia in Inguinal Hernia Repair
Status: UNKNOWN
Conditions: Post Operative Pain
Interventions: PROCEDURE: Transversalis fascia plane (TFP) block|PROCEDURE: Erector Spinae Plane (ESP) Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Combination Effect of Platelet-rich Plasma and Hyaluronic Acid for Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: platelet rich plasma + Hyaluronic acid|DRUG: platelet rich plasma + normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy and the Safety of Antihypertensive Tablets
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: OJP-2028
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vest Prevention of Early Sudden Death Trial and VEST Registry
Status: COMPLETED
Conditions: Myocardial Infarction|Ventricular Dysfunction|Sudden Death|Ventricular Tachycardia|Ventricular Fibrillation
Interventions: DEVICE: wearable defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Intestinal Bacterial and Fungal Translocation and Intestinal Microbiota in Febrile Neutropenic Patients in Pediatric Onco-hematology
Status: TERMINATED
Conditions: Febrile Neutropenia
Interventions: DIAGNOSTIC_TEST: Evaluation of microbial translocation and microbiota
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Effect Induced by Repeated Administration of Topical Local Anaesthetic (EMLA) on Itch
Status: COMPLETED
Conditions: Lidocaine|Itch
Interventions: DRUG: EMLA (lidocaine) +Itch (Histamine and cowhage)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Increasing Mean Arterial Pressure on Renal Function in Patients With Shock and With Elevated Central Venous Pressure
Status: NOT_YET_RECRUITING
Conditions: Shock
Interventions: PROCEDURE: increase of mean arterial pressure at 65-70 mmHg|PROCEDURE: increase of mean arterial pressure at 80-85 mmHg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Adapting the Shed-MEDS Deprescribing Intervention to Dementia Care in Assisted Living
Status: RECRUITING
Conditions: Polypharmacy|Dementia|Quality of Life
Interventions: BEHAVIORAL: Shed-MEDS deprescribing intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Green Tea Buccal Tablets in Oral Lichen Planus
Status: UNKNOWN
Conditions: Oral Lichen Planus
Interventions: DRUG: green tea buccal tablet|DRUG: Corticosteroids Topical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid Determination Of The Clinical Utility Of Perampanel For The Treatment Of Alcohol Dependence
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: Perampanel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Coordinating Center for Enhancing ADRD Caregiving
Status: COMPLETED
Conditions: Dementia|Alzheimer Disease
Interventions: PROCEDURE: Skill Training Condition - problem solving training|PROCEDURE: REACH for TLC (Telephone Linked Computer) system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate Patient Preference, Satisfaction And Efficacy Of a Nasal Aerosol Versus an Aqueous Nasal Spray
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: ciclesonide|DRUG: mometasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melatonin Effects on Genital Herpes in Brazilian Women
Status: COMPLETED
Conditions: Genital Herpes
Interventions: COMBINATION_PRODUCT: Melatonin 3 mg|DRUG: Acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Subcutaneous Daratumumab in Combination With Standard Multiple Myeloma Treatment Regimens
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Bortezomib|DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Melphalan|DRUG: Prednisone|DRUG: Carfilzomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Community Intervention Trial of Multimodal Suicide Prevention Program in Japan (NOCOMIT-J)
Status: COMPLETED
Conditions: Suicide
Interventions: BEHAVIORAL: Multimodal suicide prevention program|BEHAVIORAL: Suicide prevention program as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: StaphVAX Immunogenicity and Safety in Orthopaedic Joint Surgery
Status: COMPLETED
Conditions: Staphylococcal Infections
Interventions: BIOLOGICAL: S. aureus Types 5 and 8 Capsular Polysaccharide Conjugate|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ProspeCtive, nOn-randoMized, MulticENter Clinical Evaluation of Edwards Pericardial Bioprostheses With a New Tissue Treatment Platform (COMMENCE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Stenosis|Mitral Stenosis|Aortic Valve Insufficiency|Mitral Valve Insufficiency|Heart Failure
Interventions: DEVICE: Edwards Aortic and Mitral Bioprostheses Models 11000A and 11000M
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lamivudine Plus Adefovir Versus Telbivudine Plus Adefovir in Lamivudine Resistant Chronic Hepatitis B
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: telbivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of 23-valent Pneumococcal Polysaccharide Vaccine
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: Investigational 23-valent PPV|BIOLOGICAL: Control 23-valent PPV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bemalenograstim Alfa for the Prevention in Patients With Colorectal Cancer/Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Pancreatic Cancer
Interventions: DRUG: Bemalenograstim alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Continuous Adductor Canal Block (CACB) vs. Combined Spinal Epidural (CSE) in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Arthroplasty
Interventions: PROCEDURE: Continuous Adductor Canal Block|PROCEDURE: General|PROCEDURE: Epidural|PROCEDURE: Spinal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Temperature and Humidity Among Different Anesthesia Work-station
Status: UNKNOWN
Conditions: Humidity|Temperature
Interventions: DEVICE: Datex Ohmeda excel anesthesia machine|DEVICE: Datex Ohmeda Avance anesthesia work-station|DEVICE: Drager Cato anesthesia work-station|DEVICE: Drager Primus anesthesia work-station
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Study of ALLO-ASC-SHEET in Subjects With Diabetic Foot Ulcers
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: BIOLOGICAL: ALLO-ASC-DFU|PROCEDURE: Hydrogel SHEET(Vehicle control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Clinical Trial of the Group A Meningococcal Polysaccharide Vaccine
Status: UNKNOWN
Conditions: Meningitis, Meningococcal
Interventions: BIOLOGICAL: Experimental Group A meningococcal polysaccharide vaccine|BIOLOGICAL: Control Group A meningococcal polysaccharide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nitric Oxide Control of Migrating Motor Complex: L-NMMA Effects in Relation to Receptor Blockades
Status: COMPLETED
Conditions: Gastrointestinal Motility Disorder|Disturbance of Salivary Secretion
Interventions: BIOLOGICAL: L-Nitro-Monomethyl-Arginine (LNMMA) 10 mg/kg IV|BIOLOGICAL: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Dual Task Training on Balance, Activity and Participation in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Dual task training|OTHER: Dual task training with backward walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine and Gemcitabine in Treating Patients With Metastatic Kidney Cancer
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: DRUG: capecitabine|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Hypercholesterolaemia in Hispanic Subjects (STARSHIP)
Status: COMPLETED
Conditions: Hypercholesterolemia|Dyslipidaemia
Interventions: DRUG: Rosuvastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study of Fimasartan/Amlodipine/Hydrochlorothiazide in Healthy Male Subjects
Status: COMPLETED
Conditions: Drug-Drug Interaction
Interventions: DRUG: Fimasartan/Amlodipine combination drug, Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Niuliva® for the Prevention of Hepatitis B Virus Recurrence in Newly Orthotopic Liver Transplant Recipients
Status: COMPLETED
Conditions: Hepatitis B|Liver Transplantation
Interventions: DRUG: Hepatitis B immune globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Conservative Versus Surgical Treatment of Umbilical Pilonidal Disease
Status: COMPLETED
Conditions: Pilonidal Sinus|Sinus; Dermal, Pilonidal|Umbilical Granuloma
Interventions: PROCEDURE: Surgery|OTHER: conservative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing TVT With TVT-SECUR for the Treatment of Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: tension-free vaginal tape|DEVICE: TVT-SECUR device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vagus Stimulation in Female Long COVID Patients.
Status: RECRUITING
Conditions: Vagus Nerve Diseases|Long COVID|Long Covid19|Post-COVID-19 Syndrome|Post-COVID Syndrome|Post COVID-19 Condition|Post COVID Condition
Interventions: DEVICE: transcutaneous electrical vagal neurostimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Demonstrate the Efficacy and Safety of Motilitone®
Status: COMPLETED
Conditions: Functional Dyspepsia
Interventions: DRUG: Motilitone ®|DRUG: Pantoline®|DRUG: Motilitone® and Pantoline®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Systematic Dexamethasone on the Duration of Popliteal Nerve Block for Anesthesia After Pediatric Ankle Surgery
Status: COMPLETED
Conditions: Ankle Disease|Foot Deformities|Foot Diseases|Cerebral Palsy
Interventions: DRUG: Sodium Chloride 0.9% Inj|DRUG: 0,1mg/kg Dexamethasone|DRUG: 0,2mg/kg Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial to Reduce Environmental Tobacco Smoke in Children With Asthma
Status: COMPLETED
Conditions: Asthma|Lung Diseases
Interventions: DEVICE: HEPA Air Cleaner|DEVICE: Placebo Filtration Unit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: VAC Bioburden Wound Care Assessment
Status: TERMINATED
Conditions: Upper Extremity Wound|Lower Extremity Wound|Soft Tissue Abscesses|Traumatic Wounds
Interventions: DEVICE: Wound Vac is applied
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Effect of a Probiotic on Upper Respiratory Tract Infections in Healthy Children
Status: RECRUITING
Conditions: Upper Respiratory Tract Infections|Upper Resp Tract Infection
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CPG 7909 + Local Radiotherapy in Recurrent Low-Grade Lymphomas
Status: COMPLETED
Conditions: Non-Hodgkin Lymphoma|Mycosis Fungoides
Interventions: DRUG: CPG 7909
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Active Transport Educational Program Based on the Ecological Model on Improving the Physical and Mental Health: MOV-ES Project
Status: NOT_YET_RECRUITING
Conditions: Physical Inactivity in Children
Interventions: OTHER: Active transport educational program based on the ecological model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Mindfulness-Based Stress Reduction Program (MBSR) in Risky Pregnants
Status: COMPLETED
Conditions: Stress|Pregnancy, High Risk
Interventions: BEHAVIORAL: Mindfullness Based Stress Reduction (MBSR) intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Efficacy and Safety in Patients With Advanced Breast Cancer Treated With SYHX2011 Compared to Paclitaxel for Injection (Albumin-bound)
Status: NOT_YET_RECRUITING
Conditions: Advanced Breast Cancer
Interventions: DRUG: SYHX2011|DRUG: Paclitaxel for injection (albumin-bound)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Mobile Health (mHealth) and Clinic-Based Self-Management Interventions for Serious Mental Illness
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Bipolar Disorder|Major Depressive Disorder
Interventions: BEHAVIORAL: FOCUS (Smartphone Application)|BEHAVIORAL: WRAP (Wellness Recovery Action Planning)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Naushero Feroze Neonatal Survival Project
Status: COMPLETED
Conditions: Birth Asphyxia|Very Low Birth Weight Baby|Neonatal Sepsis
Interventions: BEHAVIORAL: Intervention|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Inhaled Steroid Reduces Systemic Inflammation in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Emphysema|Chronic Bronchitis
Interventions: DRUG: inhaled fluticasone 500 mcg b.i.d.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Levels of Pain and Discomfort Between Two Methods of Correcting Misaligned Teeth
Status: COMPLETED
Conditions: Malocclusion|Crowded Teeth|Surgical Incision
Interventions: PROCEDURE: Piezosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Safety of Two Applications of PEP005 Topical Gel to Actinic Keratoses
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: PEP005|DRUG: PEP005|DRUG: PEP005|DRUG: PEP005|DRUG: PEP005|DRUG: PEP005|DRUG: PEP005|DRUG: PEP005
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Backtracking Leukemia-Typical Somatic Mutations in Cord Blood
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia
Interventions: OTHER: Cord blood Sample Collection|OTHER: Case identification and recruitment|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cardiovascular Magnetic Resonance Guided Open Artery Trial for Revascularization of Late Presenting ST Elevation Myocardial Infarction
Status: WITHDRAWN
Conditions: STEMI
Interventions: OTHER: Cardiovascular Magnetic Resonance Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the 25 Centimeter (cm) GORE® VIABAHN® Endoprosthesis
Status: COMPLETED
Conditions: Peripheral Vascular Diseases
Interventions: DEVICE: 25 cm GORE® VIABAHN®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-based Management of Female Stress Urinary Incontinence
Status: COMPLETED
Conditions: Female Stress Urinary Incontinence
Interventions: BEHAVIORAL: Web-based treatment with PFMT and elements of CBT|BEHAVIORAL: Pamphlet treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fingolimod in Minimal Invasive Treatment of Intracerebral Hemorrhage
Status: NOT_YET_RECRUITING
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: Fingolimod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Helicobacter Pylori Eradication According to DPO-PCR Methods (K-CREATE) Study)
Status: RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Duration of eradication regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exparel Use in Adductor Canal Block After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Arthritis Knee|Pain, Postoperative|Opioid Use
Interventions: DRUG: Exparel|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study for the Optimal Treatment of Symptomatic Patients With Low Gradient Severe Aortic Valve Stenosis and Preserved Left Ventricular Ejection Fraction
Status: TERMINATED
Conditions: Aortic Valve Stenosis
Interventions: PROCEDURE: aortic valve replacement|OTHER: strict clinical surveillance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Microvascular Complications in Prediabetes e-PREDICE Study
Status: UNKNOWN
Conditions: PreDiabetes
Interventions: DRUG: Placebo, metformin, linagliptin, linagliptin + metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Ascending Dose Study of RO4905417 in Healthy Volunteers and Patients With Peripheral Arterial Disease (PAD).
Status: COMPLETED
Conditions: Peripheral Arterial Disease (PAD)
Interventions: DRUG: RO4905417|DRUG: RO4905417|DRUG: RO4905417|DRUG: placebo|DRUG: placebo|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tolperisone in Acute Muscle Spasm of the Back
Status: COMPLETED
Conditions: Back Pain|Acute Pain|Back Spasm Upper Back|Back Strain|Muscle Cramp|Muscle Spasm|Low Back Pain
Interventions: DRUG: Tolperisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of E6011 in Japanese Subjects With Primary Biliary Cholangitis Inadequately Responding to Ursodeoxycholic Acid
Status: TERMINATED
Conditions: Primary Biliary Cholangitis
Interventions: DRUG: E6011|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MPAACS: Magnesium for the Prevention of Atrial Arrhythmias After Cardiac Surgery
Status: TERMINATED
Conditions: Coronary Artery Disease|Valvular Heart Disease
Interventions: DRUG: intravenous magnesium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Abiraterone Acetate Plus Prednisone With or Without Abemaciclib (LY2835219) in Participants With Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Abemaciclib|DRUG: Abiraterone Acetate|DRUG: Prednisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's of Choice Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer (VIRO-25)
Status: NOT_YET_RECRUITING
Conditions: Advanced Non-squamous Non-small-cell Lung Cancer|Advanced Squamous Non-Small Cell Lung Carcinoma|Metastatic Non-squamous Non Small Cell Lung Cancer|Metastatic Squamous Non-Small Cell Lung Carcinoma|Non-small Cell Lung Cancer|Non-small Cell Lung Cancer Stage III|Non-small Cell Lung Cancer Stage IV|Non-small Cell Lung Cancer Recurrent
Interventions: BIOLOGICAL: Olvimulogene nanivacirepvec|DRUG: Platinum chemotherapy: carboplatin or cisplatin|DRUG: Non-platinum chemotherapy: paclitaxel or nab-paclitaxel for squamous cell NSCLC or pemetrexed for nonsquamous cell NSCLC|DRUG: Physician's Choice of Immune Checkpoint Inhibitor: pembrolizumab, nivolumab, cemiplimab, atezolizumab, durvalumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Dose Safety Study of BMS-962476 in Healthy Subjects and Patients With Elevated Cholesterol on Statins
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: BIOLOGICAL: BMS-962476|BIOLOGICAL: Placebo matching with BMS-962476
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Inflammation and Damage to Lymph Node Structures on Durable Protective Immunity Following Yellow Fever Vaccination
Status: ACTIVE_NOT_RECRUITING
Conditions: Yellow Fever
Interventions: BIOLOGICAL: Yellow Fever Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Testing MLN0128 (TAK-228) as Potentially Targeted Treatment in Cancers With TSC1 or TSC2 Genetic Changes (MATCH - Subprotocol M)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lymphoma|Advanced Malignant Solid Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Multiple Myeloma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Sapanisertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Evaluation of Dose-response and Safety of Dry Powder Inhalation of Treprostinil
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Inhaled dry powder treprostinil (LIQ861)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Pembrolizumab in Combination With Cisplatin and Pemetrexed in Advanced Malignant Pleural Mesothelioma (MPM) (MK-3475-A17)
Status: COMPLETED
Conditions: Mesothelioma
Interventions: DRUG: Pembrolizumab|DRUG: Pemetrexed|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlling Anal Incontinence by Performing Anal Exercises With Biofeedback or Loperamide (CAPABLe)
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: DRUG: Loperamide|DRUG: Placebo|BEHAVIORAL: Anal exercises with biofeedback|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Diphtheria, Tetanus, Pertussis (DTaP) Vaccine in 3-month-old Infants
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: Diphtheria, tetanus and acellular pertussis (component) combined vaccine (adsorbed)|BIOLOGICAL: Diphtheria, tetanus and acellular pertussis combined vaccine (adsorbed)|BIOLOGICAL: Diphtheria, tetanus, pertussis (acellular, component), poliomyelitis (inactivated) vaccine (adsorbed) and Haemophilus influenzae type b conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Simtuzumab (SIM) With FOLFIRI as Second Line Treatment in Colorectal Adenocarcinoma
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: Simtuzumab|DRUG: Placebo to match SIM|DRUG: Leucovorin|DRUG: Irinotecan|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Zoladex™ 10.8 mg With Zoladex 3.6 mg in Pre-menopausal Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: ZD9393 (Zoladex) 10.8 mg|DRUG: ZD9393 (Zoladex) 3.6 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketone Supplementation and Exercise Performance
Status: UNKNOWN
Conditions: Ketosis|Exercise Performance|Ketoses, Metabolic
Interventions: BEHAVIORAL: 10 km time trial|BEHAVIORAL: 30s Wingate|DIETARY_SUPPLEMENT: Ketone|BEHAVIORAL: Baseline 10 km time trial|BEHAVIORAL: Baseline 30s Wingate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Low-dose Interleukin-2 and Rapamycin on sjögren's Syndrome
Status: COMPLETED
Conditions: Sjögren's Syndrome
Interventions: DRUG: low-dose interleukin-2|DRUG: rapamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Effects of KUR-101 in Healthy Adults
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: KUR-101|DRUG: OxyNorm|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Topical Otic Drop Use at Time of Tympanostomy Tube Surgery Improve Outcomes When no Middle Ear Effusion is Present
Status: RECRUITING
Conditions: Otitis Media
Interventions: DRUG: Ofloxacin otic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PREventing Pain After Surgery
Status: RECRUITING
Conditions: Pain, Back|Spinal Stenosis|Disc Herniation|Spondylosis|Spondylolisthesis|Back Injuries
Interventions: BEHAVIORAL: ACT intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of GS-2121 Given Alone or in Combination in Adults With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: GS-2121|DRUG: Zimberelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Itacitinib in Combination With Corticosteroids for Treatment of Graft-Versus-Host Disease in Pediatric Subjects
Status: TERMINATED
Conditions: Acute Graft-versus-host Disease
Interventions: DRUG: Itacitinib|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drinking Water Chlorination and Child Survival in Rural Kenya
Status: COMPLETED
Conditions: Death|Diarrhea|Child Development
Interventions: BEHAVIORAL: Water Treatment|BEHAVIORAL: Sanitation|BEHAVIORAL: Handwashing|DIETARY_SUPPLEMENT: Nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: REGorafenib vsTamoxifen in Patients With Platinum-sensitive OVARian Carcinoma and Isolated Biological Progression
Status: COMPLETED
Conditions: Ovarian Carcinoma
Interventions: DRUG: Tamoxifen|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expanded Access of Vigil in Solid Tumors
Status: TEMPORARILY_NOT_AVAILABLE
Conditions: Solid Tumor|Ewing Sarcoma|Ewing's Tumor Metastatic|Ewing's Sarcoma Metastatic|Advanced Gynecological Cancers|Ovarian Cancer|Cervical Cancer|Uterine Cancer
Interventions: BIOLOGICAL: Vigil
Study Type: EXPANDED_ACCESS
Clinical trial: Systems Biology of Vaccination for EV71 Vaccine in Humans
Status: COMPLETED
Conditions: Systems Biology|Early Gene|EV71 Vaccine
Interventions: BIOLOGICAL: 320U /0.5ml|BIOLOGICAL: 0/0.5ml placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic and Pharmacodynamic Evaluation of Formulations of Δ9-THC
Status: NOT_YET_RECRUITING
Conditions: Nausea Post Chemotherapy|Vomiting|Cancer Pain|Cancer Related Pain|Neoplasms
Interventions: DRUG: Pharmacokinetic and pharmacodynamic profile of THC oral formulations with Dronabinol as comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acupuncture in Treating Hot Flashes in Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Hot Flashes
Interventions: PROCEDURE: acupuncture therapy|PROCEDURE: hot flashes attenuation|PROCEDURE: management of therapy complications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cisplatin and Everolimus in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: cisplatin|DRUG: everolimus|GENETIC: gene expression analysis|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-operative Adjuvant Treatment for HPV-positive Tumours (PATHOS)
Status: RECRUITING
Conditions: Human Papillomavirus (HPV)-Positive Oropharyngeal Cancer
Interventions: DRUG: Cisplatin|RADIATION: Postoperative radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity And Safety of COVID-19 Vaccine , Inactivated Co -Administration With EV71 Vaccine (Vero Cell)
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Experimental Group|BIOLOGICAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Paroxysmal Nocturnal Hemoglobinuria in ESUS & ETUS
Status: ACTIVE_NOT_RECRUITING
Conditions: Paroxysmal Nocturnal Hemoglobinuria|Embolic Stroke of Undetermined Source|Transient Ischemic Attack|Cerebral Vein Thrombosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Toca 5 Trial: Toca 511 & Toca FC Versus Standard of Care in Patients With Recurrent High Grade Glioma
Status: TERMINATED
Conditions: Glioblastoma Multiforme|Anaplastic Astrocytoma
Interventions: BIOLOGICAL: Toca 511|DRUG: Toca FC|DRUG: Lomustine|DRUG: Temozolomide|BIOLOGICAL: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Predicting Response to Tamoxifen and Letrozole in Postmenopausal Women With Primary Breast Cancer Treated on Clinical Trial CAN-NCIC-MA17
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: GENETIC: microarray analysis|GENETIC: polymerase chain reaction|GENETIC: protein expression analysis|OTHER: diagnostic laboratory biomarker analysis|OTHER: fluorescent antibody technique|OTHER: immunohistochemistry staining method|OTHER: immunologic technique
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Investigation on the Impact on Safety, Feasibility and Usability of the Design Changes Performed on ABLE Exoskeleton Device With Spinal Cord Injured Patients in a Hospital Setting
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DEVICE: ABLE Exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Minimally Invasive Superficial Venous Insufficiency Surgery and Digital Sedation
Status: RECRUITING
Conditions: Superficial Venous Insufficiency
Interventions: DEVICE: use of a device incorporating virtual reality software|DRUG: Neuroleptanalgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exploratory Study to Determine Tissue Alterations of Advanced Hepatocellular Carcinoma Induced by Electromagnetic Waves of Low Energy Amplitude Modulated to Specific Frequencies During Imaging Study by MRI
Status: COMPLETED
Conditions: Primary or Metastatic Tumor in the Liver Parenchyma
Interventions: PROCEDURE: Magnetic Resonance + hemodynamic + infusion of gadolinium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Adjuvant Docetaxel-Zoledronic Acid in High-risk Early Prostate Cancer Following Prostatectomy.
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Zoledronic Acid|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pediatric Concussion Outcomes
Status: TERMINATED
Conditions: Concussion Post Syndrome|Headaches Posttraumatic|Mild Traumatic Brain Injury
Interventions: DRUG: Nortriptyline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Apple Consumption on Cardiovascular Health in Prediabetics and Type 2 Diabetics
Status: COMPLETED
Conditions: Diabetes|Cardiovascular Diseases|Prediabetes
Interventions: DIETARY_SUPPLEMENT: Apple|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tositumomab And Iodine I 131-Tositumomab In Patients With Relapsed Indolent Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: Tositumomab 450 mg|DRUG: Tositumomab 35 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF
Status: NOT_YET_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease|Chronic Heart Failure
Interventions: BEHAVIORAL: Mindful Steps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Audio-visual Stimulation: Sleep Dose Response
Status: COMPLETED
Conditions: Insomnia Chronic|Osteoarthritis|Pain, Chronic
Interventions: DEVICE: Audiovisual Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of an Individualized Vaccine Targeting Neoantigens in Combination With Immune Checkpoint Blockade for Patients With Colon Cancer
Status: TERMINATED
Conditions: Colonic Neoplasms|Colorectal Neoplasms
Interventions: DRUG: GRT-C901|DRUG: GRT-R902|DRUG: Atezolizumab|DRUG: Ipilimumab|DRUG: Adjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemoradiotherapy in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Paclitaxel|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Multi-center, Multi-regional Observational Study to Test the Responsiveness of the Validated MusiQoL (Multiple Sclerosis International Quality of Life Questionnaire) Instrument to EDSS Status Changes in Any Form of Multiple Sclerosis (MS) in Patients With or Without Treatment
Status: COMPLETED
Conditions: Multiple Sclerosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prazosin as an Antimanic Agent in Severe Mania or Mixed States
Status: WITHDRAWN
Conditions: Bipolar, Mania|Bipolar, Mixed State
Interventions: DRUG: Addition of prazosin to usual care (add-on study)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Articular Sonography: Healthy Subjects Versus Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Disorders of Synovium, Multiple Sites|Disorders of Subchondral Bone, Multiple Sites|Disorders of Cartilage, Hand Joints|Arthritis, Rheumatoid|Healthy People
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Relationship Between ABCG2 Mutation and Teriflunomide Exposure and Safety in Chinese RMS Patients Treated With Teriflunomide 14 mg Once Daily for 24 Weeks
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: TERIFLUNOMIDE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Using Recombinant Human Luteinizing Hormone (r-hLH, Luveris®) in the Treatment of Chinese Women With Hypogonadotropic Hypogonadism
Status: COMPLETED
Conditions: Hypogonadism
Interventions: DRUG: Recombinant human luteinizing hormone (r-hLH)|DRUG: Recombinant human follicle-stimulating hormone (r-hFSH)|DRUG: Human chorionic gonadotropin (hCG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sodium Bicarbonate Supplementation in Combat Sports Athletes
Status: COMPLETED
Conditions: Supplementation|Sport
Interventions: DIETARY_SUPPLEMENT: Sodium bicarbonate supplementation|DIETARY_SUPPLEMENT: Placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intratreatment FDG-PET During Radiation Therapy for Gynecologic and Gastrointestinal Cancers
Status: RECRUITING
Conditions: Cancer of the Cervix|Vulvar Cancer|Esophageal Cancer|Anal Canal Cancer
Interventions: OTHER: FDG PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy Study of an Interactive Wound Dressing (KC002) for the Treatment of Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Foot Ulcer|Diabetes
Interventions: DEVICE: KC-002|OTHER: Conventional Wound Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimum Misoprostol Dose Prior to Office Hysteroscopy
Status: COMPLETED
Conditions: Infertility|Abnormal Uterine and Vaginal Bleeding, Unspecified|Recurrent Abortion
Interventions: DRUG: Misoprostol|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pregnancy-Related Low Back Pain and Complementary and Alternative Medicine (CAM) Treatment
Status: COMPLETED
Conditions: Low Back Pain
Interventions: BEHAVIORAL: Exercise|PROCEDURE: Spinal Manipulation|PROCEDURE: Neuroemotional Technique (NET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal Progesterone Versus Placebo in Multiple Pregnancy
Status: COMPLETED
Conditions: Preterm Birth
Interventions: DRUG: Vaginal progesterone gel|DRUG: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy of Tiotropium + Olodaterol Fixed Dose Combination (FDC) Over Tiotropium in Improvement of Lung Hyperinflation, Exercise Capacity and Physical Activity in Japanese COPD Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: tiotropium|DRUG: olodaterol|DRUG: tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 3D-Printed Patient-Specific Surgical Plates Versus Conventional Surgical Plates in Jaw Reconstruction
Status: RECRUITING
Conditions: Mandibular Neoplasms|Maxillary Neoplasms|Dentofacial Deformities
Interventions: DEVICE: 3D-printed patient-specific plate|DEVICE: Conventional commercial reconstruction plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT