pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of a Caffeine- and Protein-Containing Coffee Beverage on Metabolism and Muscular Performance
Status: COMPLETED
Conditions: Exercise Performance|Metabolism
Interventions: DIETARY_SUPPLEMENT: Beverage Consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of the Safety and Immunogenicity of Sequential Administration of Prevnar 13™ and Pneumovax™ 23 in Healthy Participants 50 Years of Age and Older (V110-029)
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: Prevnar 13™|BIOLOGICAL: Pneumovax™ 23|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Two Neuromuscular Transmission Monitors Based on Acceleromyography: TOF-Watch SX® and TOFScan®
Status: UNKNOWN
Conditions: Curarisation|Neuromuscular Monitoring
Interventions: DRUG: Rocuronium|DEVICE: Neuromuscular monitoring with TOFScan® and TOF-Watch SX®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Liver Perfusion MRI With Quantification of Tumoral Perfusion for Early Assessment of the Response of Antiangiogenics Treatments in Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: liver Perfusion MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Exoskeleton Robotic Assisted Gait Training in Spastic Stroke Post Botulinum Toxin A Injection
Status: RECRUITING
Conditions: Spastic Gait|Spastic
Interventions: PROCEDURE: BoNT-A injections|OTHER: BoNT-A injection and robot therapy|OTHER: None BoNT-A injection and robot therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of QVA149 on Exercise Tolerance in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: indacaterol and glycopyrronium bromide (QVA149)|DRUG: placebo|DRUG: tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for Malaria Vaccines to Test for Safety, Immune Response and Protection Against Malaria
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: DNA vaccine prime|BIOLOGICAL: adenovirus type 5 vaccine boost
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of 2 Different Formulations of Blosozumab (LY2541546) in Post Menopausal Women
Status: TERMINATED
Conditions: Osteoporosis, Postmenopausal
Interventions: BIOLOGICAL: Blosozumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Docetaxel/Prednisone to Docetaxel/Prednisone in Combination With OGX-011 in Men With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Custirsen|DRUG: Docetaxel|DRUG: Prednisone|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Violence Against Health Care Workers in Fragile Settings
Status: RECRUITING
Conditions: Workplace Violence
Interventions: BEHAVIORAL: Training in de-escalating violence|BEHAVIORAL: Code of conduct delivered via a warning board
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Anti-CD19, Dual Co-stimulatory (4-1BB, CD3ζ) Chimeric Antigen Receptor T-cells in Patients With Relapsed/Refractory Aggressive Lymphoma or Acute Lymphoblastic Leukemia (ALL)
Status: RECRUITING
Conditions: Relapsed Non Hodgkin Lymphoma|Relapsed Adult ALL|Relapsed Pediatric ALL
Interventions: BIOLOGICAL: autologous CD19-directed chimeric antigen receptor (CAR) T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Insomnia Treatment on Brain Responses During Resting-state and Cognitive Tasks
Status: RECRUITING
Conditions: Chronic Insomnia
Interventions: BEHAVIORAL: Cognitive-Behavioural therapy for insomnia (CBT-I)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Femoral Block Following Total Knee Arthroplasty (TKA)
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: PROCEDURE: Femoral Block|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexmedetomidine on Emergence Agitation in Children With or Without Tube Insertion Under General Anesthesia
Status: COMPLETED
Conditions: Myringotomy
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Wear of a Highly Cross-linked Polyethylene Acetabular Doped With Vitamin E and Coated With Titanium in Total Hip Replacement
Status: UNKNOWN
Conditions: Total Hip Replacement
Interventions: DEVICE: standard polyethylene acetabular irradiated at 3 Mrad|OTHER: radio stereometric analysis (RSA) of the acetabular|DEVICE: acetabular polyethylene vitamys®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Robot-Assisted Rehabilitation of Hand Paralysis After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Experimental group|DEVICE: Control group|DEVICE: traditional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and Pharmacokinetics of Rifaximin in Patients With Moderate-to-severe Papulopustular Rosacea
Status: COMPLETED
Conditions: Papulopustular Rosacea
Interventions: DRUG: Rifaximin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of AZD9833 Alone or in Combination in Women With Advanced Breast Cancer.
Status: ACTIVE_NOT_RECRUITING
Conditions: ER+ HER2- Advanced Breast Cancer
Interventions: DRUG: AZD9833|DRUG: AZD9833|DRUG: AZD9833 with palbociclib|DRUG: AZD9833 with palbociclib|DRUG: AZD9833 with everolimus|DRUG: AZD9833 with everolimus|DRUG: AZD9833 with abemaciclib|DRUG: AZD9833 with abemaciclib|DRUG: AZD9833 with capivasertib|DRUG: AZD9833 with capivasertib|DRUG: AZD9833 with ribociclib|DRUG: AZD9833 with ribociclib|DRUG: AZD9833 with anastrozole|DRUG: AZD9833 with anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefits of Different Exercise Types to Enhance Walking for PD
Status: RECRUITING
Conditions: Parkinson Disease|Gait Disorders, Neurologic
Interventions: BEHAVIORAL: Gait + aerobic exercise|BEHAVIORAL: Gait + resistance exercises|BEHAVIORAL: Gait + conventional physical therapy|BEHAVIORAL: Gait + rest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Concomitant Administration of Bivalent COVID-19 Vaccines With Influenza Vaccines
Status: COMPLETED
Conditions: Immune Response|Safety
Interventions: BIOLOGICAL: bivalent BNT162b2 mRNA original/omicron BA.4-5 vaccine|BIOLOGICAL: quadrivalent influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prevalence and Clinical Associates of Iron Deficiency in Patients With Atrial Fibrillation
Status: UNKNOWN
Conditions: Iron-deficiency|Atrial Fibrillation
Interventions: DIAGNOSTIC_TEST: Ferritin, iron and iron binding capacity, high sensitive C-reactive protein (CRP) measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of an Antioxidant Formulation on Ocular Blood Flow
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma
Interventions: DIETARY_SUPPLEMENT: dietary supplement with antioxidants|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Alternative Dosing Regimens of Subcutaneous Azacitidine for Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TRial on the Endocrine Activity of Neoadjuvant Degarelix
Status: COMPLETED
Conditions: Breast Cancer Invasive Nos
Interventions: DRUG: triptorelin|DRUG: degarelix|DRUG: letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of a Shiitake Extract on Lipid Profile in Subjects With Moderate Hyperlipidemia
Status: COMPLETED
Conditions: Hypercholesterolemia|Hyperlipidemias|Dietary Supplements|Cardiovascular Risk Factor
Interventions: DIETARY_SUPPLEMENT: Experimental product|DIETARY_SUPPLEMENT: Placebo product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Montelukast and Azelastine in Treatment of Moderate to Severe Allergic Rhinitis
Status: UNKNOWN
Conditions: Allergic Rhinitis
Interventions: DRUG: Montelukast|DRUG: Azelastine|DRUG: Budesonide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The DECRA Trial: Early Decompressive Craniectomy in Patients With Severe Traumatic Brain Injury
Status: COMPLETED
Conditions: Brain Injuries
Interventions: PROCEDURE: Early decompressive craniectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Estimation of the Prevalence of HIV, Hepatitis C and Hepatitis B Infection Among Detainees in the Nîmes Administrative Detention Center
Status: COMPLETED
Conditions: HIV Infections|Hepatitis C|Hepatitis B
Interventions: DIAGNOSTIC_TEST: Rapid diagnosis test against HIV and hepatitis C and B
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Weekly TP-HDFL in the Treatment of Advanced TCC
Status: COMPLETED
Conditions: Transitional Cell Carcinoma
Interventions: DRUG: Paclitaxel, Cisplatin, 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cost-Effectiveness of Rotator Cuff Repair Methods
Status: UNKNOWN
Conditions: Rotator Cuff Injuries|Shoulder Pain|Shoulder Impingement|Shoulder Injuries|Shoulder Bursitis|Shoulder Tendinitis|Shoulder Lesions
Interventions: PROCEDURE: Rotator cuff repair surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of SmofKabiven Peripheral Versus Compounded Emulsion
Status: COMPLETED
Conditions: Parenteral Feeding|Surgery
Interventions: DRUG: SmofKabiven Peripheral|DRUG: Hospital compounded emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tanezumab in Adults With Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: BIOLOGICAL: Tanezumab 20 mg IV|DRUG: Placebo for naproxen|BIOLOGICAL: Tanezumab 10 mg IV|DRUG: Placebo for naproxen|BIOLOGICAL: Tanezumab 5 mg IV|DRUG: Placebo for naproxen|BIOLOGICAL: Placebo for tanezumab|DRUG: Naproxen|BIOLOGICAL: Placebo for tanezumab|DRUG: Placebo for naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sevoflurane-Remifentanil Interaction: Multiple Response Surfaces, Validation of Calibration Stimuli, Validation of the Intraoperative Isobole Concept and Investigating Remifentanil Induced Opioid Tolerance
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Fixed sevoflurane dose 1|DRUG: Fixed sevoflurane dose 2|DRUG: Fixed sevoflurane dose 3|DRUG: Fixed sevoflurane dose 4|DRUG: Fixed sevoflurane dose 5|DRUG: Fixed sevoflurane dose 6|DRUG: Fixed remifentanil dose 1|DRUG: Fixed remifentanil dose 2|DRUG: Fixed remifentanil dose 3|DRUG: Fixed remifentanil dose 4|DRUG: Fixed remifentanil dose 5|DRUG: Fixed remifentanil dose 6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Rectus Sheath Block to Control Postoperative Pain
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: ultrasound guided rectus sheath block|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Trilaciclib Combined With Chemotherapy in the Treatment of Advanced NSCLC With Leptomeningeal Metastasis
Status: RECRUITING
Conditions: NSCLC
Interventions: DRUG: combination of Trilaciclib and Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Golimumab (CNTO 148) in Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: CNTO 148|DRUG: Placebo|DRUG: Methotrexate (MTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness of Essure Post-NovaSure Radiofrequency Endometrial Ablation Procedure Following a Successful Essure Confirmation Test
Status: COMPLETED
Conditions: Contraception|Menorrhagia
Interventions: DEVICE: ESS305 (Essure, BAY1454032)|PROCEDURE: NovaSure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess Immunization Responses in Adult and Adolescent Participants With Moderate-to-Severe Atopic Dermatitis Treated With Nemolizumab
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: Nemolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GMB: Study of Truvada (TDF+FTC) or Emtricitabine (FTC) Alone Versus HAART Interruption in HIV-Infected Patients With Resistance
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Truvada (TDF+FTC) alone|DRUG: FTC alone|PROCEDURE: No HAART
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlled Study to Evaluate Efficacy and Safety of α-KA Tab With Low Protein Diet (LPD) in Delaying the Progress of Type 2 Diabetic Nephropathy (DN)
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: Ketosteril®|OTHER: diabetic diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Aim of This Project is to Verify Whether a Depletion of B Cell Memory Subpopulation ("Marginal-zone-like") CD19 + IgD + CD27 + and CD19 + IgM + CD27 + is a Useful Indicator of Hyposplenism in Patients With Celiac Disease
Status: UNKNOWN
Conditions: Celiac Disease
Interventions: DIAGNOSTIC_TEST: venous blood sampling|PROCEDURE: spleen volumetry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of the Acute Effect of IP
Status: COMPLETED
Conditions: Deficiency Growth Hormone
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: IP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy Study of a TXA127 to Reduce Graft-vs-Host Disease in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation
Status: WITHDRAWN
Conditions: Hematologic Malignancies
Interventions: DRUG: TXA127
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Radial Artery Versus Saphenous Vein Patency (RSVP) Trial - 10 Year Follow-up
Status: WITHDRAWN
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Coronary artery bypass (CABG) surgery using a radial arterial conduit|PROCEDURE: Coronary artery bypass surgery using a long saphenous vein conduit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY900014 (Lyumjev) Versus Insulin Lispro (Humalog) in Participants With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Lyumjev with 50% basal rate reduction|DRUG: Humalog with 50% basal rate reduction|DRUG: Humalog with 100% basal rate reduction|DRUG: Lyumjev with 100% basal rate reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Visa-versa! Breaking Instead of Pushing the Pedals-A
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: PROCEDURE: 15 minutes eccentric cycling|PROCEDURE: 15 minutes concentric (normal) cycling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Appendicectomy Skin Closure Technique: Changing Paradigms (ASC)
Status: COMPLETED
Conditions: Appendicitis
Interventions: PROCEDURE: Continuous intradermic stitch|PROCEDURE: Separated stitches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Safety, Tolerability and Pharmacodynamics of KP104 in Participants With Thrombotic Microangiopathy Secondary to Systemic Lupus Erythematosus
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: KP104
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Bioequivalence of Ethinylestradiol (EE) and Drospirenone (DRSP) in Two Different Tablet Formulations: YAZ and YAZ + Levomefolate Calcium (Metafolin) & L-5-MTHF in Two Different Tablet Formulations: Levomefolate Calcium (Metafolin) and YAZ + Levomefolate Calcium (Metafolin)
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: EE 0.02 mg/DRSP 3 mg (YAZ, BAY86-5300)|DRUG: EE 0.02 mg/DRSP 3 mg/L-5-MTHF Ca 0.451 mg (EE20/DRSP/L-5-MTHF Ca)|DRUG: L-5-MTHF 0.451mg (Metafolin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate BMS-986165 and Methotrexate in Healthy Male Patients
Status: COMPLETED
Conditions: Lupus|Psoriatic Arthritis
Interventions: DRUG: Methotrexate|DRUG: Leucovorin|DRUG: BMS-986165
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Henagliflozin and Metformin on Myocardial Tissue-level Characteristics
Status: NOT_YET_RECRUITING
Conditions: Obesity|Type 2 Diabetes|Sodium-glucose Co-transporter-2 Inhibitor|Myocardial Fibrosis|Magnetic Resonance Imaging
Interventions: DRUG: Henagliflozin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Supplementation With Probiotics as Adjuvant to Mechanical Treatment in Chronic Periodontitis
Status: COMPLETED
Conditions: Probiotics, Periodontitis
Interventions: DEVICE: Ultrasonic periodontal Debridement, with appropriate device|BIOLOGICAL: Analyzes of periodontopathogenic bacteria|GENETIC: IL1B test|BIOLOGICAL: Salivary Sampling|DEVICE: Halitosis measure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magseed Pro(R)/ Sentimag(R) Gen3
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DEVICE: Magseed Pro(R) and Sentimag(R) Gen3 by Endomagnetics
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study Evaluating the Tolerance and Biologic Activity of Oral Ciclopirox Olamine in Patients With Relapsed or Refractory Hematologic Malignancy
Status: COMPLETED
Conditions: Hematologic Malignancy|Acute Lymphocytic Leukemia|Chronic Lymphocytic Leukemia|Myelodysplasia|Acute Myeloid Leukemia|Chronic Myelogenous Leukemia|Hodgkin's Disease
Interventions: DRUG: Ciclopirox Olamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Biomarkers in Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: PROCEDURE: Lumbar Puncture (Standard-of-Care)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Screening With Whole Body MRI For Detection Of Primary Tumors In Children And Adults With Li-Fraumeni Syndrome (LFS) And Other Cancer Predisposition Syndromes
Status: ACTIVE_NOT_RECRUITING
Conditions: Li-Fraumeni Syndrome
Interventions: DEVICE: Whole Body MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Tolerability of Hypertonic Saline in Infants With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Hypertonic Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketogenic Diet With Radiation and Chemotherapy for Newly Diagnosed Glioblastoma
Status: TERMINATED
Conditions: Glioblastoma (GBM)
Interventions: DIETARY_SUPPLEMENT: Ketogenic Diet|RADIATION: Radiation therapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Ipatasertib in Combination With Atezolizumab
Status: UNKNOWN
Conditions: Solid Tumor|Glioblastoma Multiforme|Prostate Cancer Metastatic
Interventions: DRUG: ipatasertib|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Topical Tranexamic Acid in Caesarean Section
Status: UNKNOWN
Conditions: Postpartum Haemorrhage
Interventions: DRUG: Topical tranexamic acid|DRUG: Normal saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Test the Effectiveness of a New Treatment for Scalp Psoriasis
Status: SUSPENDED
Conditions: Psoriasis
Interventions: DRUG: DPS-102|OTHER: Vehicle / Placebo|DRUG: Calcipotriol Monotherapy|DRUG: Nicotinamide Monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Role of Microsurgery in Surgical Treatment of Varicocele.
Status: UNKNOWN
Conditions: Varicocele|Infertility
Interventions: PROCEDURE: subinguinal microscopic varicocelectomy|PROCEDURE: laparoscopic varicocelectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study To Examine The Safety, Pharmacokinetics And Pharmacodynamics Of PF-03635659 In Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Lung Diseases|Respiratory Tract Diseases|Chronic Obstructive Airway Disease|COPD
Interventions: DRUG: placebo|DRUG: active comparator|DRUG: Low Dose PF-03635659|DRUG: Mid Dose PF-03635659|DRUG: High Dose PF-03635659
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Disrupted Reconsolidation: Impact on Cocaine Craving
Status: COMPLETED
Conditions: Cocaine Addiction
Interventions: DRUG: Propranolol, 40 mg|DRUG: Propranolol, 80 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Between Albuterol Sulfate Inhalation Aerosol 108mcg Per Actuation and Proair HFA (Albuterol Sulfate) Inhalation Aerosol 90mcg Per Actuation in Healthy Volunteers Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Albuterol Sulfate Inhalation Aerosol 108mcg per actuation|DRUG: Proair HFA (albuterol sulfate) Inhalation Aerosol 90mcg per actuation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of an Orthotic Intervention in Children With Peripheral Neuropathy
Status: COMPLETED
Conditions: Gait, Drop Foot|Chemotherapy-induced Peripheral Neuropathy|Acute Lymphocytic Leukemia, Pediatric|Rhabdomyosarcoma|Wilms Tumor
Interventions: DEVICE: Solid ankle foot orthotic|DEVICE: Resting night splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Monotherapy With Levetiracetam or Carbamazepine in Patients Suffering From Epilepsy.
Status: COMPLETED
Conditions: Epilepsy, Tonic-clonic
Interventions: DRUG: LEVETIRACETAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: A Study of the Effect of Tirzepatide on How the Body Handles Birth Control Pills in Healthy Female Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tirzepatide|DRUG: EE/NGM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Does the Access to Small Delicious Dishes, Have a Positive Effect on Nutritional Intake in Patients at Nutritional Risk?
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: Nutritional intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Appropriate Duration of Anti-Platelet straTegy in Patients With Advance Chronic Kidney Disease After New Generation Drug Eluting Stents (ADAPT-CKD)
Status: RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: DRUG: dual anti-platelet therapy at least 6 months|DRUG: dual anti-platelet therapy 3months or less
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Ciprofloxacin (CPFX) With Cefepime (CFPM) in Febrile Neutropenic Patients With Hematologic Diseases
Status: COMPLETED
Conditions: Febrile Neutropenia
Interventions: DRUG: ciprofloxacin|DRUG: cefepime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visual Outcomes and Contrast Sensitivity in Patients Implanted With Tecnis Eyhance Intraocular Lens
Status: COMPLETED
Conditions: Intraocular Lens
Interventions: DEVICE: TECNIS Eyhance intraocular lens|DEVICE: Monofocal intraocular lens Tecnis ZCB00
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced or Metastatic Solid Tumors|Breast Cancer|Ovarian Cancer|Pancreas Cancer|Prostate Cancer
Interventions: DRUG: IDE-161
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Caplacizumab in Japanese Patients With Acquired Thrombotic Thrombocytopenic Purpura (aTTP)
Status: COMPLETED
Conditions: Thrombotic Thrombocytopenic Purpura
Interventions: DRUG: Caplacizumab (ALX-0081)|DRUG: Plasma exchange (PE)|DRUG: Corticosteroid treatment (Methylprednisolone or prednisolone)|DRUG: Immunosuppressive treatment (eg, rituximab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant TDM1 With Lapatinib and Abraxane Compared With Trastuzumab Plus Pertuzumab With Paclitaxel
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: T-DM1|DRUG: Trastuzumab|DRUG: Lapatinib|DRUG: Abraxane|DRUG: Paclitaxel|DRUG: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Resveratrol on Sirtuins and Apoptosis Biomarkers
Status: RECRUITING
Conditions: Coronary Artery Disease|Menopause|Endothelial Dysfunction
Interventions: DIETARY_SUPPLEMENT: Resveratrol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Two Treatments on the Nutritional and Micronutrient Status of Malnourished Children
Status: UNKNOWN
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: Beverage fortified with 21 vitamins and minerals|DIETARY_SUPPLEMENT: Lactose-free milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Gamma-delta T Cells Combined With Targeted Therapy and Immunotherapy in a Phase 1 Clinical Trial for First-line Treatment of Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: γδ T cells|DRUG: Targeted drugs|DRUG: PD-1 monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Early Use of the Pressure Relaxer in the Respiratory Impairment of Patients With Amyotrophic Lateral Sclerosis: Multicenter Randomized Controlled Study.
Status: NOT_YET_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DEVICE: early use of intermittent positive pressure breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Trial of the Safety and Immunogenicity of a Tetravalent Dengue Virus Vaccine Admixture TV005 in the Elderly Aged 50-70 Years in Taiwan
Status: COMPLETED
Conditions: Dengue
Interventions: BIOLOGICAL: Tetravalent live attenuated dengue vaccine admixture TV005|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Adjuvant Toripalimab Plus Chemotherapy for EGFR/ALK Mutation Negative Stage II-IIIB(N2) NSCLC (LungMate-008)
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Toripalimab|DRUG: Toripalimab mimetic (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Adjuvanted SARS-CoV-2 (SCB-2019) Vaccine in Adults With Chronic Immune-Mediated Diseases
Status: TERMINATED
Conditions: COVID-19
Interventions: BIOLOGICAL: CpG 1018/Alum-adjuvanted SCB-2019 vaccine|BIOLOGICAL: Havrix|OTHER: Placebo; 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of DCB vs DES in the Treatment of de Novo Large Diameter Coronary Atherosclerotic Stenosis(LARGE ONE)
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: SeQuent® Please drug coating balloon(DCB)，Firehawk family drug eluting stent(DES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methylprednisolone for Children With Severe Mycoplasma Pneumoniae Pneumonia (MCMP)
Status: COMPLETED
Conditions: Mycoplasma Pneumoniae Pneumonia
Interventions: DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oral Hygiene and Maternity Outcomes Multicenter Study (OHMOM)
Status: COMPLETED
Conditions: Gingivitis|Pregnancy
Interventions: DRUG: 0.243% sodium fluoride|DEVICE: toothbrush|DEVICE: dental floss|DRUG: 0.454% stannous fluoride|DEVICE: toothbrush|DRUG: 0.07% Cetylpyridinium chloride|DEVICE: dental floss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Double ABCX Theory Based Cognitive Psychotherapy Combined Progressive Muscle Relaxation Intervention on Women Undergoing IVF-ET
Status: COMPLETED
Conditions: Infertility
Interventions: BEHAVIORAL: Cognitive progressive muscular relaxation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cilengitide Imaging Trial in Glioblastoma
Status: TERMINATED
Conditions: Supratentorial Newly Diagnosed Inoperable Gliobastoma
Interventions: DRUG: Drug (including placebo)|OTHER: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Targeting Complement Activation in Antineutrophil Cytoplasmic Autoantibodies (ANCA)-Vasculitis - Eculizumab
Status: WITHDRAWN
Conditions: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Interventions: DRUG: Standard of care treatment|DRUG: eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Given With Radiation Therapy or Radiation Therapy Alone in Treating Patients With Early-Stage Hodgkin's Disease
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: bleomycin sulfate|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: prednisolone|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Subcutaneous Rapid Acting Insulin and One Formulation of Inhaled Insulin in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Technosphere Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency and Pulsed Electromagnetic Field Treatment of Skin Laxity of the Mon Pubis, Labia and Vaginal Introitus
Status: COMPLETED
Conditions: Skin Laxity
Interventions: DEVICE: Venus Freeze Diamond Polar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of PRG-1801 for Refractory Lupus Nephritis and IgG4-Related Disease
Status: RECRUITING
Conditions: Lupus Nephritis|IgG4-related Disease
Interventions: BIOLOGICAL: PRG-1801
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Melatonin on Cardiometabolic Risk- FULL
Status: UNKNOWN
Conditions: Obesity|Prediabetic State
Interventions: DRUG: Melatonin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: P53MVA and Pembrolizumab in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Platinum-Resistant Fallopian Tube Carcinoma|Recurrent Platinum-Resistant Ovarian Carcinoma|Recurrent Platinum-Resistant Primary Peritoneal Carcinoma
Interventions: BIOLOGICAL: Modified Vaccinia Virus Ankara Vaccine Expressing p53|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of CO2 Pneumoperitoneum at Different Temperature in Laparoscopic Surgery
Status: COMPLETED
Conditions: Benign Neoplasm of Cervix Uteri|Gynecological Laparoscopy
Interventions: PROCEDURE: Group HH (heated-humidified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Evaluate the Effect of Different Warm-Up Times of Risankizumab Autoinjector (AI) on the Injection Pain Experiences in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Risankizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial of SHR-1210 (an Anti-PD-1 Antibody) in Combination With Apatinib in Patients With Advanced TNBC
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: SHR-1210|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Timolol for Infantile Hemangioma in Early Proliferative Phase
Status: COMPLETED
Conditions: Hemangioma
Interventions: DRUG: Timolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Remineralization Potential of Curodont Repair Flouride Plus Versus CPP-ACP in Management of White Spot Lesions: Randomized Clinical Trial
Status: UNKNOWN
Conditions: White Spot Lesion
Interventions: DRUG: Self assembling peptide with fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Designing a Personalized Diet to Reduce the Risk of Crohn's Disease Onset
Status: NOT_YET_RECRUITING
Conditions: Diet, Healthy|High Risk
Interventions: OTHER: Mediteranean to Western to Mediteranean Diet|OTHER: Western to Mediteranean to Western Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: STEPS Trial - Spheramine Safety and Efficacy Study
Status: TERMINATED
Conditions: Parkinson Disease
Interventions: BIOLOGICAL: Spheramine (BAY86-5280)|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Relief During Photodynamic Therapy for Actinic Keratoses With a New Irradiation Protocol
Status: COMPLETED
Conditions: Therapy, Photodynamic|Keratosis, Actinic|Pain
Interventions: DEVICE: BF-RhodoLED|DEVICE: Aktilite CL128|DRUG: BF200-ALA/5-aminolevulinic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Center Study Comparing MOBIS II ST vs MOBIS PEEK
Status: WITHDRAWN
Conditions: Lumbar Disc Disease
Interventions: DEVICE: SIGNUS MOBIS PEEK Cage|DEVICE: SIGNUS MOBIS II ST Cage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Radiofrequency Ablation of Breast Cancer Lumpectomy Sites to Decrease Re-operation
Status: COMPLETED
Conditions: Cancer of the Breast
Interventions: DEVICE: AngioDynamics (previously RITA Med,Inc) radiofrequency delivery system (consisting of a generator and Starburst XL probe)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cockroach Immunotherapy in Children and Adolescents
Status: COMPLETED
Conditions: Persistent Asthma
Interventions: BIOLOGICAL: German cockroach allergenic extract|BIOLOGICAL: Placebo for German cockroach allergenic extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Magtrace®/Sentimag® in Sentinel Node Biopsy for Malignant Melanoma. The Magmen Study.
Status: COMPLETED
Conditions: Melanoma|Sentinel Lymph Node
Interventions: DEVICE: SLN Biopsy with Magtrace®/Sentimag®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vitamin D Status of Pregnant Women and Their Children in Eau Claire, South Carolina
Status: COMPLETED
Conditions: Vitamin D Deficiency|Pregnancy
Interventions: DRUG: cholecalciferol (vitamin D3)|DRUG: cholecalciferol|DRUG: cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Incidence of Hepatitis B Virus (HBV) Reactivation in HBsAg Negative/HBcAb Positive Lymphoma Patients Treated With RCHOP
Status: UNKNOWN
Conditions: Lymphoma
Interventions: DRUG: nucleoside analog reverse transcriptase inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Radiation Therapy for Heterotopic Ossification Prophylaxis Acutely After Elbow Trauma
Status: TERMINATED
Conditions: Elbow Fracture
Interventions: RADIATION: Radiation Therapy (XRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Coordinated Vaccination Against RSV and Influenza in Patients With Chronic Heart Failure and Its Impact on Prognosis.
Status: RECRUITING
Conditions: Heart Failure|RSV Infection|Influenza|Vaccines
Interventions: BIOLOGICAL: Coordinated Vaccination|BEHAVIORAL: Following recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Face Perception and Impact of Surgical Masks in Preterm Infants
Status: NOT_YET_RECRUITING
Conditions: Visual Preference With and Without Mask in Term Infant|Visual Preference With and Without Mask in Preterm Infant
Interventions: OTHER: Presentation of differents face pictures
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Plasma Volume Determination by 99mTc-labeled Albumin and 125I-labeled Albumin
Status: COMPLETED
Conditions: Healthy
Interventions: RADIATION: Plasma volume determination (99mTc-albumin)|RADIATION: Plasma volume determination (125I-albumin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ePRO-based Model of Care to Manage and Monitoring Symptoms of Cancer Patients Treated With Immune Checkpoint Inhibitors
Status: UNKNOWN
Conditions: Patient Reported Outcome Measures|Patient Safety
Interventions: DEVICE: Electronic Patient-reported Outcomes-based Model of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transoral Fundoplication Prior to Sleeve Gastrectomy Versus RNY Gastric Bypass on GERD Symptoms in Bariatric Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastroesophageal Reflux Disease
Interventions: PROCEDURE: Transoral Fundoplication and Sleeve Gastrectomy|PROCEDURE: Gastric Bypass
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The "Light for the Brain" Study
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplantation|Cognitive Impairments|Sleep|Depression|Fatigue|Quality of Life
Interventions: DEVICE: Intervention systematic light exposure|DEVICE: Comparison systematic light exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chiglitazar/Metformin in Non-obese Women With PCOS
Status: ENROLLING_BY_INVITATION
Conditions: Polycystic Ovary Syndrome|Chiglitazar|Metformin
Interventions: DRUG: Chiglitazar|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT