pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pharmacokinetics of Piperacillin/Tazobactam in Patients Treated by Continuous Renal Replacement Therapy
Status: COMPLETED
Conditions: Diffusive and Convective Clearance|Body Clearance|Piperacillin Tazocilline Concentrations (Cmin)
Interventions: DRUG: piperacillin/tazobactam|PROCEDURE: Pharmacokinetic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Follow up of Water Vapor Thermal Therapy (Rezum) for Benign Prostatic Hyperplasia (BPH)
Status: ACTIVE_NOT_RECRUITING
Conditions: Benign Prostatic Hyperplasia
Interventions: PROCEDURE: water vapor thermal therapy (Rezum) for prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Typical Spinal Block During Cesarean Delivery
Status: ENROLLING_BY_INVITATION
Conditions: Cesarean Section|Anesthesia, Obstetric
Interventions: DRUG: Intrathecal 1.6 ml 0.75% bupivacaine in 8.25% dextrose combined with 15 mcg fentanyl and 150 mcg preservative-free morphine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2a, Proof-of-Concept Study of GIC-1001 in the Management of Visceral Pain During Sedation-Free, Full Colonoscopy
Status: COMPLETED
Conditions: Pain|Cancer|Colonic Diseases
Interventions: DRUG: GIC-1001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of UCB0942 in Adult Patients With Highly Drug-resistant Focal Epilepsy
Status: COMPLETED
Conditions: Highly Drug-resistant Focal Epilepsy
Interventions: DRUG: UCB0942|DRUG: UCB0942|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of an Inactivated COVID-19 Vaccine in People Aged ≥18 Years With HIV Infected
Status: UNKNOWN
Conditions: HIV Infections|COVID-19
Interventions: BIOLOGICAL: Inactivated COVID-19 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Efficacy and Safety of Immunoadsorption and Plasma Exchange for Acute Attack of Refractory Neuromyelitis Optica Spectrum Disorders
Status: NOT_YET_RECRUITING
Conditions: Neuromyelitis Optica Spectrum Disorder
Interventions: DEVICE: blood purification equipment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Functional Neuroanatomy of the Human Physiological Stress Response
Status: RECRUITING
Conditions: Hypoglycemia|Physiological Stress
Interventions: OTHER: Hypoglycemic Hyperinsulinemic Clamp|OTHER: Normoglycemic Hyperinsulinemic Clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pharmacokinetic Study of Cefepime After Administration Into Dialysate in Patients With Continuous Ambulatory Peritoneal Dialysis (CAPD) Peritonitis
Status: COMPLETED
Conditions: Peritonitis
Interventions: DRUG: Intraperitoneal Cefepime
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Research Study Looking Into Blood and Urine Levels of the Medicine NNC0194-0499 in the Body and How Well it is Tolerated in Participants With Reduced Kidney Function and Normal Kidney Function
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis (NASH)
Interventions: DRUG: NNC0194-0499
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of Acute Encephalopathy Predictors in Patients With COVID-19
Status: COMPLETED
Conditions: Encephalopathy|COVID
Interventions: DIAGNOSTIC_TEST: CT-scan|DIAGNOSTIC_TEST: EEG|DIAGNOSTIC_TEST: EP|DIAGNOSTIC_TEST: Pulse oximetry|DIAGNOSTIC_TEST: Blood tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of a High Density Mapping System to Complete Wide Area Circumferential Ablation of the Pulmonary Veins and Avoid Ostial Segmental Ablation
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Atrial Fibrillation Ablation|DEVICE: Catheters used to isolate pulmonary veins|PROCEDURE: Atrial Fibrillation Ablation with HD mapping to isolate PVs|DEVICE: Rhythmia HD mapping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Multi-Ctr PII Cmb.Modality Tx Ruxolitinib, Decitabine, and DLI for Post HSCT in AML/MDS
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myeloid and Monocytic Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: Decitabine|DRUG: Ruxolitinib|DRUG: Donor Lymphocyte Infusion (DLI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tele-group Cognitive Behavioural Family Intervention (tgCBFI) for People With Schizophrenia and Their Families
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia|Psychosis
Interventions: BEHAVIORAL: tgCBFI|BEHAVIORAL: Usual psychiatric care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Analyses of Mirtazapine in NSCLC Patients With Depression
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung|Depression
Interventions: DRUG: Mirtazapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Migration Potential of Xeomin® Compared to Two Other Botulinum Toxin Type A Products
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Botulinum neurotoxin type A, free of complexing proteins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose:
Clinical trial: Autonomic Small Fiber Neuropathy and Ehlers Danlos Syndromes - Prospective Study and Registry
Status: RECRUITING
Conditions: Autonomic Neuropathy|Ehlers-Danlos Syndrome Hypermobility Type|Small Fiber Neuropathy|Postural Tachycardia Syndrome
Interventions: OTHER: No intervention planned, but all patients get our standart treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Autonomic Modulation on Symptoms in Patients With Reflux Hypersensitivity
Status: COMPLETED
Conditions: Gastro Esophageal Reflux
Interventions: BEHAVIORAL: slow deep breathing|BEHAVIORAL: sham breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized, Controlled Multi-center Study of ArtiFascia® Dural Repair Patch Compared With Commercially Available Dural Substitutes. To Evaluate the Safety and Effectiveness of ArtiFascia® in Subjects Requiring Dural Repair.
Status: COMPLETED
Conditions: Dural Tear|Cerebrospinal Fluid Leak
Interventions: DEVICE: Implantation of the ArtiFascia®|DEVICE: Implantation of other commercial suturable dural substitute
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Optimal Relaxation Technique for Laparotomies With Rocuronium Infusion Followed by Sugammadex Reversal
Status: COMPLETED
Conditions: Underdosing of Skeletal Muscle Relaxants for Laparotomy|Reversal of Skeletal Muscle Relaxant
Interventions: DRUG: Neostigmine, atropine|DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Relational Research Recruitment and Engagement Intervention for Cognitive Aging Research
Status: COMPLETED
Conditions: Dementia|Cognitive Dysfunction|Alzheimer Disease|Lewy Body Disease|Frontotemporal Dementia
Interventions: OTHER: Relational Research Recruitment and Engagement Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Assessing Cognitive and Health Improvements in the Elderly Via Exercise (ACHIEVE) - Study.
Status: COMPLETED
Conditions: Aging|Exercise
Interventions: OTHER: Exercise Dose-Response
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sedative-Anxiolytic Effects on Simulated Driving Performance
Status: COMPLETED
Conditions: Psychomotor Impairment
Interventions: DRUG: Alprazolam 2mg (2ALP/PLC)|DRUG: Alprazolam 1mg (1ALP/PLC)|DRUG: Alprazolam 0.5mg (0.5ALP/PLC)|DRUG: Zolpidem 10mg (ZOL/PLC)|DRUG: Placebo (PLC/PLC)|DRUG: Alprazolam 1mg (PLC/ALC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacies of Susceptibility-guided vs Empiric Therapy for Rescue Treatment of Helicobacter Pylori Infection
Status: RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: susceptibility-guided tailored therapy (Group A)|DRUG: guidelines-recommended empiric therapy (Group B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Colonization Capacity of a Probiotic Bacterium.
Status: NOT_YET_RECRUITING
Conditions: Obese|Weight, Body
Interventions: DIETARY_SUPPLEMENT: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accelerated vs Non-Accelerated Rehabilitation After Anterior Cruciate Ligament Reconstruction: A Pilot Study
Status: TERMINATED
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: OTHER: Accelerated Rehabillitation|OTHER: Non-Accelerated Rehabillitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on Patient-Specific-Instrumentation Assisted Lapidus Fusion for Hallux Valgus
Status: ACTIVE_NOT_RECRUITING
Conditions: Hallux Valgus|Bunion|Patient Spe
Interventions: PROCEDURE: PSI Lapidus|PROCEDURE: Conventional Lapidus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Nepafenac in Reducing Macular Volume After Epiretinal Membrane Surgery
Status: COMPLETED
Conditions: Epiretinal Membrane
Interventions: DRUG: Nepafenac 0.1%|OTHER: BSS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Study of Image-Guided Radiation Concurrent With Double-Agent Chemotherapy for Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Carcinoma, Hepatocellular
Interventions: RADIATION: IGRT|DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of High Intensity Exercise Rehabilitation on Liver Function and Insulin Sensitivity in Patients With MASLD
Status: RECRUITING
Conditions: Exercise Therapy|Metabolic Dysfunction-associated Steatotic Liver Disease
Interventions: OTHER: Combined aerobic + strength training|OTHER: Combined strength + HIIT training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Prenatal Vitamin/Mineral Supplements on Perinatal Mortality
Status: COMPLETED
Conditions: Perinatal Mortality|Stillbirth|Neonatal Mortality
Interventions: DIETARY_SUPPLEMENT: folic acid|DIETARY_SUPPLEMENT: folic acid plus iron|DIETARY_SUPPLEMENT: supplements with multiple vitamins and minerals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tricyclic Antidepressants (TCAs) on Gastric Emptying
Status: TERMINATED
Conditions: Dyspepsia
Interventions: DRUG: Desipramine|DRUG: Amitriptyline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Triptorelin for Preserving Ovarian Function in Premenopausal Women Receiving Chemotherapy for Early-Stage Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Hormone Changes|Drug Toxicity
Interventions: DRUG: triptorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioavailability and Food Effect of the Original Gelatin Formulation and Two New Formulations of Afuresertib in Normal Healthy Volunteers
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Afuresertib GC - Fasted State|DRUG: Afuresertib HPMC capsule - Fasted State|DRUG: Afuresertib ECT - Fasted State|DRUG: Afuresertib GC - Fed State|DRUG: Afuresertib HPMC capsule - Fed State|DRUG: Afuresertib ECT - Fed State
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of the Safety, Pharmacokinetics, and Anti-Tumor Activity of TH-302 in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Tumors|Hypoxia
Interventions: DRUG: TH-302
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Put a Face to a Name (Part A): The Effects of Photographic Aids on Patient Satisfaction, Clinician Communication, and Quality of Care
Status: COMPLETED
Conditions: Effects of Photographic Aids (Photos of Faces) on Patient Recall of Their Clinical Care Team|Effects of Photographic Aids (Photos of Faces) on Clinician-patient Communication|Effects of Photographic Aids (Photos of Faces) on Overall Patient Satisfaction
Interventions: OTHER: Provision of Clinical Care Handout
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: VItamin D Effect on Osteoarthritis Study
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Vitamin D|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a New Cardiac Pacemaker
Status: UNKNOWN
Conditions: Atrial Fibrillation With 2 or 3° AV or Bifascicular Bundle Branch (BBB) Block|Normal Sinus Rhythm With 2 or 3° AV or BBB Block|Sinus Bradycardia With Infrequent Pauses or Unexplained Syncope With EP Findings
Interventions: DEVICE: Pacemaker implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effects of Robotic Exoskeleton-Assisted Gait Re-habilitation and Predictive Factors of Significant Improvements in Stroke Patients
Status: RECRUITING
Conditions: Stroke Sequelae
Interventions: DEVICE: Robotic exoskeleton-assisted gait rehabilitation|OTHER: Conventional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Bioavailability Study of Film-coated Tablet and Granule Formulations of RG1662
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: RG1662 granules|DRUG: RG1662 tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Health Effects From Removal of Amalgam Restorations in Patients With Symptoms Allegedly Related to Dental Amalgam
Status: COMPLETED
Conditions: Adverse Effects|Dental Restoration, Permanent
Interventions: PROCEDURE: Removal of dental amalgam restorations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediately Placed Implant Sealed With Platelets Rich Fibrin Versus Cyanoacrylate Glue
Status: UNKNOWN
Conditions: Tooth Socket
Interventions: OTHER: Cyanoacrylate glue|OTHER: Platelet-rich fibrin (PRF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Vagal Stimulation for Frequent Premature Ventricular Complexes
Status: RECRUITING
Conditions: Premature Ventricular Contraction
Interventions: DEVICE: Parasym device|DEVICE: Sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes for Offering Genetic Testing in a Tiered Approach
Status: COMPLETED
Conditions: Breast Carcinoma|Colon Carcinoma|Malignant Solid Neoplasm|Ovarian Carcinoma|Pancreatic Carcinoma|Prostate Carcinoma
Interventions: OTHER: Electronic Health Record Review|OTHER: Questionnaire Administration|BEHAVIORAL: Behavioral Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine
Status: TERMINATED
Conditions: Pruritus
Interventions: DRUG: Ketamine Hydrochloride|DRUG: Amitriptyline Hydrochloride|DRUG: Lidocaine Hydrochloride|COMBINATION_PRODUCT: Ketamine hydrochloride, Amitriptyline hydrochloride, and Lidocaine hydrochloride|DRUG: Lipoderm Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ezetimibe-Ursodiol Combination Therapy on Biomarkers of Liver Function and Sterol Balance in Subjects With NAFLD
Status: TERMINATED
Conditions: Nonalcoholic Fatty Liver Disease (NAFLD)
Interventions: DRUG: EZ-Urso combination therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Protein Intake on Protein Metabolism During Intensified Training
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Normal|DIETARY_SUPPLEMENT: Moderate|DIETARY_SUPPLEMENT: High|OTHER: Controlled-diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Endometrial Injury for Assisted Reproduction
Status: TERMINATED
Conditions: Infertility
Interventions: PROCEDURE: Endometrial injury|PROCEDURE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Acute Kidney Injury - Molecular Mechanisms of Dietary Pre-conditioning in Human
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: low-calorie formula diet|DIETARY_SUPPLEMENT: protein-restricted diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Endovenous Water Vapor Treatment on Quality of Life in Superficial Venous Insufficiency of the Lower Limbs
Status: UNKNOWN
Conditions: Venous Insufficiency of Leg
Interventions: DEVICE: VBox Hybrid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Cardiovascular Events in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Cardiovascular Disease
Interventions: OTHER: Baseline serum vitamin D level below 50 nmol/l|OTHER: Baseline serum vitamin D level at or above 50 nmol/l
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prebiotic Fiber Supplement in T1DM Children
Status: UNKNOWN
Conditions: Type 1 Diabetes
Interventions: DIETARY_SUPPLEMENT: Prebiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Hope and Expectations in Open-Label Placebos
Status: COMPLETED
Conditions: Pain
Interventions: OTHER: DP|OTHER: OLP Hope|OTHER: OLP Expectation|OTHER: Placebo cream|OTHER: Heat pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain
Status: UNKNOWN
Conditions: Cancer
Interventions: DRUG: ketamine hydrochloride|OTHER: pharmacogenomic studies|OTHER: questionnaire administration|PROCEDURE: assessment of therapy complications|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Ovarian Reserve and Recurrence Rate After DWLS Diode Laser OMA Vaporization
Status: COMPLETED
Conditions: Endometrioma|Ovarian Endometriosis|Ovarian Endometrioma
Interventions: PROCEDURE: laparoscopic endometrioma laser vaporization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Lopinavir/ Ritonavir and Lamivudine Versus Standard Therapy in Naïve HIV-1 Infected Subjects.
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: lopinavir/ritonavir plus one nucleoside|DRUG: lopinavir /ritonavir plus two nucleosides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Safety and Efficacy of HOE901-U300 With Lantus in Children and Adolescents With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Insulin glargine,300 U/mL|DRUG: Insulin glargine (100 units /mL)|DRUG: Background therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CACAF2 Study: Catheter Ablation for Cure of Atrial Fibrillation
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: DEVICE: RF ablation|DRUG: Antiarrhythmic drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 6-Month Chronic Efficacy & Safety Study of Eszopiclone in Adult Subjects With Primary Insomnia
Status: COMPLETED
Conditions: Primary Insomnia
Interventions: DRUG: Eszopiclone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Active and Passive Music Therapy Interventions
Status: COMPLETED
Conditions: Autonomic Nervous System Imbalance|Hypothalamic Pituitary Adrenal Axis Suppression
Interventions: BEHAVIORAL: Active Music Therapy|BEHAVIORAL: Passive Music Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Black Cohosh and Red Clover for the Relief of Menopausal Symptoms
Status: COMPLETED
Conditions: Hot Flashes|Menopause
Interventions: DRUG: Cimicifuga racemosa|DRUG: Trifolium pratense|DRUG: Black cohosh|DRUG: Red clover
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Autologous Cultured Adipose -Derived Stem Cells for the Crohn's Fistula
Status: COMPLETED
Conditions: Crohn's Fistula
Interventions: BIOLOGICAL: ADIPOPLUS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Herbal Products on Reduction of Radiation-induced Dermatitis in Breast Cancer Patients
Status: COMPLETED
Conditions: Radiodermatitis|Breast Neoplasms|Adverse Effect of Radiation Therapy
Interventions: OTHER: Control|OTHER: Cucumber cream|OTHER: Centella cream|OTHER: Thunbergia cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Objective and Subjective Changes Induced by Multiple Pinhole Glasses and Single Pinhole Glasses
Status: UNKNOWN
Conditions: Functional Vision Changes
Interventions: DEVICE: Trayner Pinhole Glasses (Trayner Glasses, Ivybridge Devon, U.K.)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Efficacy of Oral Rotavirus Vaccine 116E (ROTAVAC 5D) in Chilean Infants
Status: RECRUITING
Conditions: Rotavirus Infection of Children
Interventions: BIOLOGICAL: ROTAVAC 5D|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention of Mandibular Third Molar Extraction- Associated Periodontal Defects Using Platelet-Rich Fibrin
Status: COMPLETED
Conditions: Periodontal; Lesion|Periodontal Pocket|Molar, Third
Interventions: PROCEDURE: extraction of mandibular third molar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Well-Formulated Ketogenic Diet Polycystic Kidney Disease
Status: RECRUITING
Conditions: Polycystic Kidney Disease
Interventions: OTHER: Ketogenic Diet|BIOLOGICAL: Ketone/Glucose Monitoring|BIOLOGICAL: CGM/CKM|BIOLOGICAL: Blood Draw|OTHER: Body Composition|OTHER: Change in glomerular filtration rate (mg/mmol) via magnetic resonance imaging (MRI) .
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of Belotecan/Cisplatin in Chemotherapy Naive Small Cell Lung Cancer Patient
Status: COMPLETED
Conditions: Carcinoma, Small Cell
Interventions: DRUG: Belotecan|DRUG: Etoposide|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Complementary Management of Chronic Neck and/or Low Back Pain With a Pain Relief Kit
Status: TERMINATED
Conditions: Pain, Chronic|Musculoskeletal Pain|Low Back Pain|Neck Pain
Interventions: BEHAVIORAL: multimodal non-pharmacological Pain Relief Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess a PI3Kδ Inhibitor (IOA-244) in Patients With Metastatic Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor, Adult|Non-Hodgkin Lymphoma, Adult|NSCLC|Myelofibrosis|Uveal Melanoma
Interventions: DRUG: IOA-244|DRUG: Avelumab Injection|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Effect of Ultrasound Therapy on Bilateral Masseter Myalgia: Randomized Single Blinded Investigational Trial
Status: COMPLETED
Conditions: Temporomandibular Joint Dysfunction Syndrome
Interventions: DEVICE: Ultrasound Sonicator 740
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Effects of Two Iron Preparations on Protein in the Urine
Status: COMPLETED
Conditions: Kidney Failure, Chronic|Anemia, Iron-Deficiency
Interventions: DRUG: iron sucrose injection, USP|DRUG: sodium ferric gluconate complex in sucrose injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Genetic Based Analysis in Hypertensive Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension|Renal Denervation|Genetic Predisposition
Interventions: GENETIC: Genetic based analysis of identifying predictors of blood pressure in patients after renal denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Effects of Epetraborole on the QT Interval in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Epetraborole and matching placebo|DRUG: Epetraborole|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Journaling on Health-Related Mood and Clinical Outcomes in Post-MI Patients
Status: COMPLETED
Conditions: Myocardial Infarction|Psychosocial Factors
Interventions: BEHAVIORAL: Gratitude Journaling Plus SOC|BEHAVIORAL: Memorable Events Journaling Plus SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study for Crossability of Spherical Tip Versus Regular Noncompliant Balloon in Tortuous Coronary Artery Postdilatation
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: Spherical tip noncompliant balloon|DEVICE: Regular noncompliant balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Nerve Stimulating Approach and Interfascial Injection Approach During Sono-guided Obturator Nerve Block
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DEVICE: nerve stimulator (stimuplex HNS12)|DEVICE: ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Dystonia Treatment With Injections Supplemented By Transcranial Magnetic Stimulation
Status: COMPLETED
Conditions: Cervical Dystonia
Interventions: DEVICE: rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Superior Venous Access, Midline vs Ultrasound IVs
Status: TERMINATED
Conditions: Vascular Access Complication|Ultrasound Therapy; Complications
Interventions: DEVICE: Ultrasound Guided Peripheral IV Catheter|DEVICE: Midline Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Belgian Trial Evaluating the ClearLumen II Peripheral Thrombectomy System Recanalization of (Sub)Acute Thrombotic Femoropopliteal Occlusions
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: ClearLumen II Peripheral Thrombectomy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Insulin Independence Trial (IIT) Evaluating the Safety and Efficacy of Oral Cyclosporine and Oral Omeprazole for Insulin Independence Among Recent Onset Type 1 Diabetes Patients
Status: WITHDRAWN
Conditions: Type 1 Diabetes
Interventions: DRUG: Oral Cyclosporine and Oral Omeprazole|DRUG: Oral Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Selected Rehabilitation Program in Patients With Plantar Fasciitis
Status: NOT_YET_RECRUITING
Conditions: Plantar Fascitis|Plantar Fasciitis, Chronic|Heel Pain Syndrome
Interventions: OTHER: stretching exercises|DEVICE: ultrasound|OTHER: rigid tape|OTHER: mobilization|OTHER: myofascial release|OTHER: strengthening exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Individualized Drug Treatment for Treating Patients With Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: capecitabine|DRUG: docetaxel|DRUG: Erlotinib|DRUG: Gemcitabine|DRUG: Irinotecan|DRUG: mitomycin C|DRUG: rapamycin|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study to Evaluate Efficacy and Safety of Gepotidacin to Nitrofurantoin in Treatment of Uncomplicated Urinary Tract Infection (UTI)
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DRUG: Gepotidacin|DRUG: Placebo matching nitrofurantoin|DRUG: Nitrofurantoin|DRUG: Placebo matching gepotidacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First-line Treatment With Camrelizumab + Apatinib Versus Chemotherapy + Bevacizumab in Advanced Cervical Cancer
Status: RECRUITING
Conditions: Stage IVB Cervical Cancer|Recurrent Cervical Cancer|Persistent Cervical Cancer
Interventions: DRUG: Camrelizumab|DRUG: Apatinib|DRUG: Paclitaxel|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Localization and Guided Injection for Superior Cluneal Nerve Entrapment
Status: RECRUITING
Conditions: Low Back Pain|Nerve Entrapment Syndrome
Interventions: OTHER: Ultrasound guided hydrodissection of superior cluneal nerve
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Klebsiella Pneumoniae Tetravalent Bioconjugate Vaccine (Kleb4V)
Status: COMPLETED
Conditions: Klebsiella Pneumoniae Infection
Interventions: BIOLOGICAL: Kleb4V target dose|BIOLOGICAL: Kleb4V target dose + AS03|BIOLOGICAL: Kleb4V low dose|BIOLOGICAL: Kleb4V low dose + AS03|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective, Multi-Center Evaluation of the Efficacy of Peripheral Trigger Decompression Surgery for Migraine Headaches
Status: COMPLETED
Conditions: Migraine Headaches
Interventions: DRUG: Botulinum Toxin Type A|PROCEDURE: Surgery|OTHER: Daily headache diary|OTHER: Migraine Disability Assessment Test (MIDAS)|OTHER: Migraine Work and Productivity Loss Questionnaire (MWPLQ)|OTHER: Migraine-Specific Quality of Life Questionnaire (MSQ)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interaction of Bexagliflozin With Metformin, Glimepiride and Sitagliptin
Status: COMPLETED
Conditions: Type2 Diabetes Mellitus
Interventions: DRUG: Bexagliflozin|DRUG: Metformin|DRUG: Glimepiride|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Zoledronic Acid and Raloxifene on Bone Turnover Markers in Postmenopausal Women With Low Bone Mineral Density
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Raloxifene|DRUG: Zoledronic acid|DRUG: Placebo oral pills|DRUG: Placebo intravenous (i.v.) infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: School-Based Telemedicine Enhanced Asthma Management
Status: COMPLETED
Conditions: Pediatric Asthma
Interventions: OTHER: School-Based Telemedicine Enhanced Asthma Management|OTHER: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Opioid Treatment for Chronic Low Back Pain and the Impact of Mood Symptoms
Status: COMPLETED
Conditions: Chronic Low Back Pain|Degenerative Disc Disease|Depression|Anxiety
Interventions: DRUG: Oxycodone|DRUG: Morphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physiology and Therapeutic Management of Neonatal Abstinence Syndrome
Status: COMPLETED
Conditions: Neonatal Abstinence Syndrome
Interventions: DEVICE: Stochastic Vibrotactile Stimulation (SVS)|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Oral LBH589 in Adult Patients With Advanced Hematological Malignancies
Status: COMPLETED
Conditions: Lymphoma|Leukemia|Multiple Myeloma
Interventions: DRUG: LBH589
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Innovative Medical Device Supporting Orthopedic Surgical Interventions
Status: COMPLETED
Conditions: Fracture of Distal End of Radius
Interventions: PROCEDURE: Treatment with investigational method (virtual implant positioning system)|PROCEDURE: Treatment with surgical standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evolution of Plasma Lipid Profile in Patients With HIV1 Who Change Atripla to Eviplera Compared to Continue With Atripla
Status: COMPLETED
Conditions: HIV-1
Interventions: DRUG: efavirenz + emtricitabina + tenofovir|DRUG: rilpivirina + emtricitabina + tenofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Inverted Vision on Pointing and Grasping in Parabolic Flight
Status: UNKNOWN
Conditions: Pointing Task|Gasping Task
Interventions: PROCEDURE: INVERTED VISION|PROCEDURE: NORMAL VISON
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Feasibility Window Study of Pembrolizumab Prior to Second Evacuation for Post-molar Gestational Trophoblastic Neoplasia
Status: RECRUITING
Conditions: Gestational Trophoblastic Disease|Gestational Trophoblastic Neoplasia|Gestational Trophoblastic Tumor, Recurrent
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Robot-based Wrist Rehabilitation in Orthopaedics: Efficacy and Comparison With Traditional Methods
Status: COMPLETED
Conditions: Wrist Injuries
Interventions: DEVICE: Specific wrist rehabilitation by WRISTBOT device|OTHER: Specific wrist rehabilitation performed by the physiotherapist|OTHER: General rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Prevention With Statin and Incidence of Recurrent MI and Cardiogenic Shock in Post-ACS Patients
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Recurrent Myocardial Infarction|Cardiogenic Shock
Interventions: DRUG: Statin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Clinical Efficacy and Safety of 100% Cassia Alata Extract Against Tinea Versicolor
Status: NOT_YET_RECRUITING
Conditions: Tinea Versicolor
Interventions: DRUG: Cassia alata extract|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The CEASE Study: Computer Based Educational Module for the Reduction of Arthralgia Syndrome Associated With Endocrine Therapy for Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Arthralgia
Interventions: BEHAVIORAL: Education and exercise intervention|BEHAVIORAL: Education and General Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Gynecologic Cancer Lymphedema Questionnaire as a Clinical Care Tool to Identify Lower Extremity Lymphedema
Status: COMPLETED
Conditions: Ovarian Cancer|Uterine Cancer|Vaginal Cancer|Lymphedema
Interventions: BEHAVIORAL: limb volume measurements and GCLQ lymphedema symptom assessment questionnaire|BEHAVIORAL: GCLQ lymphedema symptom assessment questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lidocaine Patch Versus Intravenous Lidocaine in Pain Relief After Cesarean Section
Status: UNKNOWN
Conditions: Cesarean Section Complications
Interventions: DRUG: lidocaine patch|DRUG: IV lidocaine|DRUG: IV saline infusion +Sham patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of TEAS on Chronic Pain and Survival in Patients Undergoing Hepatectomy
Status: RECRUITING
Conditions: Liver Cancer
Interventions: DEVICE: TEAS group|DEVICE: sham group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study to Confirm the Efficacy and Safety of Linzagolix to Treat Endometriosis-associated Pain
Status: TERMINATED
Conditions: Endometriosis
Interventions: DRUG: 75 mg linzagolix tablet|DRUG: 200 mg linzagolix tablet|DRUG: Add-back capsule (E2 1 mg / NETA 0.5 mg)|DRUG: Placebo tablet to match 75 mg linzagolix tablet|DRUG: Placebo tablet to match 200 mg linzagolix tablet|DRUG: Placebo capsule to match Add-back capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of High Intensity Interval Training in the Treatment of Adolescent Obesity
Status: COMPLETED
Conditions: Pediatric Obesity|Adolescent Obesity|Weight Loss
Interventions: BEHAVIORAL: High-Intensity Interval Training|BEHAVIORAL: Moderate-Intensity Continuous Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Association Between Right Atrial Reservoir Strain Variation and Fluid Responsiveness in Patients With Septic Shock
Status: RECRUITING
Conditions: Fluid Responsivness|Right Ventricle
Interventions: OTHER: Transthoracic echocardiography (TTE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Hanapū Study: Incentivized Partnerships to Reduce Diabetes Disparities
Status: COMPLETED
Conditions: Diabetes
Interventions: OTHER: Ma ka hana ka ̒ike|OTHER: Hanapū Provider Toolbox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of Continuous Glucose Monitoring in Non-Diabetic Population to Compliment Signos Mobile Health Platform
Status: RECRUITING
Conditions: Weight Loss|Metabolic Syndrome|Pre-diabetes|Central Obesity|Glucose Intolerance|Metabolic Glucose Disorders
Interventions: DEVICE: Continuous Glucose Monitor Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Magnetic Resonance Tissue Characterization in COVID-19 Survivors
Status: RECRUITING
Conditions: COVID-19 Pneumonia|COVID-19|COVID-19 Respiratory Infection|COVID-19 Acute Respiratory Distress Syndrome|COVID-19 Lower Respiratory Infection|COVID-19 Acute Bronchitis|Coronavirus Disease 2019
Interventions: DIAGNOSTIC_TEST: Cardiac MRI|DIAGNOSTIC_TEST: Echocardiogram|DIAGNOSTIC_TEST: 6-minute walk test|DIAGNOSTIC_TEST: Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Association of Mood With Risk for Atherosclerosis
Status: COMPLETED
Conditions: Mood Disorders|Hypertension|Overweight and Obesity|Vascular Stiffness|Sleep|Elevated Blood Pressure
Interventions: DIAGNOSTIC_TEST: Cardiovascular Assessments|DIAGNOSTIC_TEST: Actigraphy|DIAGNOSTIC_TEST: Laboratory assessments|BEHAVIORAL: Emotional/ Behavioural assessments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Umbrella Study to Determine the Safety and Efficacy of Various Monotherapy or Combination Therapies in Neoadjuvant Urothelial Carcinoma
Status: TERMINATED
Conditions: Urothelial Carcinoma
Interventions: DRUG: retifanlimab|DRUG: epacadostat|DRUG: INCAGN02385|DRUG: INCAGN02390
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine if Technosphere® Inhalation Powder (FDKP) Causes ECG Changes (QTc) Following the Medication's Inhaled Administration.
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Technosphere Inhalation Powder (FDKP)|DRUG: Moxifloxacin|DRUG: Technosphere Inhalation Powder (FDKP)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enzalutamide Plus Talazoparib for the Treatment of Hormone Sensitive Prostate Cancer (ZZ-First)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: Enzalutamide|DRUG: Talazoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT