pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy of Hypno-ear-acupuncture on Insomnia in Advanced Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Oncology|Insomnia|Symptoms and Signs
Interventions: PROCEDURE: Hypno-ear-acupuncture|PROCEDURE: Sham Hypno-ear-acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare Different Soft Tissue Grafts at the Time of Lateral Ridge Augmentation Procedure.
Status: COMPLETED
Conditions: Bone Graft; Complications, Infection or Inflammation|Ridge Deficency|Dental Implant
Interventions: PROCEDURE: Connective tissue graft at time of bone graft|PROCEDURE: Acellular Demal Matrix at time of bone graft|PROCEDURE: No soft tissue grafting at time of bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of PEG-rhG-CSF in Preventing Neutropenia After Chemotherapy in Patients With Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Non Hodgkin's Lymphoma
Interventions: DRUG: PEG-rhG-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Accuracy of Lumbar Pedicle Screw Placement Assisted With Continuous Pulse-train Stimulation
Status: UNKNOWN
Conditions: Spine Pedicle Screw Placement
Interventions: PROCEDURE: Electric pulse train stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Studying Blood and DNA Samples From Patients With Breast Cancer Treated With Chemotherapy With or Without Trastuzumab
Status: COMPLETED
Conditions: Breast Cancer
Interventions: GENETIC: DNA analysis|GENETIC: gene expression analysis|GENETIC: polymerase chain reaction|OTHER: enzyme-linked immunosorbent assay|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Autologous EBV-specific Cytotoxic T Cells for the Treatment of Systemic Lupus Erythematosus (SLE)
Status: TERMINATED
Conditions: Serologically Active Adult Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Autologous EBV specific CTL infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety of Human Allogeneic Bone-Marrow-Derived Mesenchymal Stromal Cell Product StromaForte for the Treatment of Knee Osteoarthritis
Status: RECRUITING
Conditions: Osteo Arthritis Knee
Interventions: BIOLOGICAL: Human Allogenic Bone-Marrow-Derived Mesenchymal Stromal Cell Product (StromaForte)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Α Pre CE-Marking Study Using the Rontis Drug Coated Balloon for Treatment of Lesions in Femoropopliteal Arteries
Status: UNKNOWN
Conditions: Peripheral Artery Disease (PAD)
Interventions: DEVICE: Rontis DCB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Oxygen Concentrations on Lung Ultrasound Score During Spontaneous Ventilation
Status: COMPLETED
Conditions: Pulmonary Atelectasis
Interventions: OTHER: %80 Oxygen concentration|OTHER: %100 Oxygen concentration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: An Investigational Scan (68Ga-DOTATATE PET/CT) in Diagnosing Pediatric Metastatic Neuroendocrine Tumors
Status: RECRUITING
Conditions: Ganglioneuroblastoma|Ganglioneuroma|Neuroblastoma
Interventions: PROCEDURE: Computed Tomography|DRUG: Gallium Ga 68-DOTATATE|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Isotonic Solutions and Major Adverse Renal Events Trial in the Medical Intensive Care Unit
Status: COMPLETED
Conditions: Critical Illness|Acute Kidney Injury
Interventions: OTHER: 0.9% Saline|OTHER: Physiologically-balanced isotonic crystalloid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Web-based Program to Help Caregivers of Lung Patients Learn About Available Supportive Care Resources
Status: ENROLLING_BY_INVITATION
Conditions: Stage II Lung Cancer|Stage III Lung Cancer|Stage IV Lung Cancer
Interventions: OTHER: Support for Caregiver - Generic List|OTHER: Support for Caregiver - Personalized List|OTHER: Internet-Based Intervention - CONNECT|BEHAVIORAL: Patient Navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Irreversible Electroporation(IRE) For Unresectable Extremities Neoplasms
Status: COMPLETED
Conditions: Extremities Neoplasms
Interventions: PROCEDURE: Irreversible electroporation (IRE)|DEVICE: NanoKnife
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Simplifying the World Health Organization (WHO) Protocol for Hand Hygiene: Three Steps and 15 Seconds
Status: COMPLETED
Conditions: Hand Hygiene
Interventions: PROCEDURE: Six-step hand hygiene technique with an application time of 30 seconds|PROCEDURE: Six-step hand hygiene technique with an application time of 15 seconds|PROCEDURE: Three-step hand hygiene technique with an application time of 30 seconds|PROCEDURE: Three-step hand hygiene technique with an application time of 15 seconds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Randomised Evaluation of COVID-19 Therapy (RECOVERY) in Children With PIMS-TS in Switzerland (SWISSPED-RECOVERY)
Status: COMPLETED
Conditions: Paediatric Inflammatory Multisystem Syndrome-Temporally Associated With SARS-CoV-2 (PIMS-TS)
Interventions: DRUG: Methylprednisolone sodium succinate 10 mg/kg intravenously|BIOLOGICAL: Human normal immunoglobulin (IVIg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Weekly Topotecan In Subjects With Recurrent Or Persistent Endometrial Cancer
Status: COMPLETED
Conditions: Neoplasms, Endometrial|Endometrial Cancer
Interventions: DRUG: topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, and Efficacy of ION-827359 in Participants With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis (CB)
Status: TERMINATED
Conditions: Chronic Bronchitis|Chronic Obstructive Pulmonary Disease
Interventions: DRUG: ION-827359|DRUG: Placebo|DRUG: ION-827359
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Lenvatinib (E7080) in Subjects With Iodine-131 Refractory Differentiated Thyroid Cancer to Evaluate Whether an Oral Starting Dose of 18 Milligram (mg) Daily Will Provide Comparable Efficacy to a 24 mg Starting Dose, But Have a Better Safety Profile
Status: COMPLETED
Conditions: Thyroid Cancer
Interventions: DRUG: Lenvatinib|DRUG: Lenvatinib matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: App-based Intervention to Promote Mental Health Help-seeking Among University Students
Status: RECRUITING
Conditions: Suicidal Ideation|Suicidal Behavior
Interventions: DEVICE: App Take Care of Your Mood|BEHAVIORAL: Reminder messages and counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Early Atrial Fibrillation Ablation for Stroke Prevention in Patients With High Comorbidity Burden (EASThigh-AFNET 11)
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation
Interventions: OTHER: Early atrial fibrillation ablation|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Virtual-reality Based Approach to Improve Behavioral Weight Management Outcomes
Status: COMPLETED
Conditions: Weight Loss
Interventions: BEHAVIORAL: Standard Behavioral Weight Loss plus Non-Weight-Related VR app|BEHAVIORAL: Standard Behavioral Weight Loss plus Weight-Related VR app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of the Living Renal Transplantation With Restored Kidneys Between Family Members
Status: UNKNOWN
Conditions: Kidney Neoplasm|Kidney Stone|Ureteral Tumor|Ureteral Stricture|Renal Insufficiency
Interventions: PROCEDURE: Restored Kidney Transplant Between Family Members
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study of INV-1120 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Cancer|Solid Tumor, Adult|Cancer Metastatic|Solid Carcinoma|Solid Tumor, Unspecified, Adult|Tumor, Solid
Interventions: DRUG: INV-1120|COMBINATION_PRODUCT: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Fat Grafting to the Breast
Status: UNKNOWN
Conditions: Micromastia|Breast Ptosis|Implant Failure|Breast Reconstruction|Congenital Malformations
Interventions: PROCEDURE: Autologous Fat Grafting to Breasts
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccination With Autologous, Lethally Irradiated Melanoma Cells Engineered by Adenoviral Mediated Gene Transfer to Secrete Granulocyte-Macrophage Stimulating Factor (GMSF)
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: Autologous, lethally irradiated melanoma cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Pilot Study to Assess the Efficacy of BOTOX-A in Patients With Low Anterior Resection Syndrome (LARS>20) and Refractory Medical Treatment After Rectal Resection
Status: TERMINATED
Conditions: Low Anterior Resection Syndrome (LARS>20)|Refractory Medical Treatment After Rectal Resection
Interventions: DRUG: BOTOX-A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Follicle Diameter on hCG Day and Follicle Diameters on OPU (Oocyte Pick up) Day and the Effect of Follicle Diameters on Embryo Development and Pregnancy Outcomes
Status: UNKNOWN
Conditions: HCG Day Follicle Diameter, Reproduction Results
Interventions: OTHER: descriptive
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Swedish Drug-elution Trial in Peripheral Arterial Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Arterial Disease|Critical Limb Ischemia|Intermittent Claudication
Interventions: PROCEDURE: Revascularization with drug-eluting technology|PROCEDURE: Revascularization without drug-eluting technology|DEVICE: drug-coated balloons and/or drug-eluting stents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Craniofacial Dimensions as Determinants of the Fitted Performance of Common Face Masks (FACEFIT 2.0)
Status: RECRUITING
Conditions: Healthy
Interventions: OTHER: Surgical/Procedure Mask Fit Testing|OTHER: KN95 Mask Fit testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pilot Feasibility Trial of Thyroid Hormone Replacement in Dialysis Patients
Status: UNKNOWN
Conditions: Thyroid Disease|Kidney Diseases, Chronic
Interventions: DRUG: Levothyroxine Sodium|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Exploring Efficacy of Pegloticase in Subjects With Asymptomatic Hyperuricemia
Status: COMPLETED
Conditions: Asymptomatic Hyperuricemia
Interventions: DRUG: SIBP-R002|DRUG: Dexamethasone or Methyl prednisolone|DRUG: Diphenhydramine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Emdogain Adjunctive to Autotransplantation
Status: RECRUITING
Conditions: Autotransplantation|Emdogain|Autologous Transplantation|Enamel Matrix Derivatives
Interventions: BIOLOGICAL: Emdogain (EMD) - test|PROCEDURE: Sham group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Brentuximab Vedotin (SGN-35) in Pediatric Participants With Relapsed or Refractory (r/r) Systemic Anaplastic Large-Cell Lymphoma or Hodgkin Lymphoma
Status: COMPLETED
Conditions: Relapsed or Refractory Hodgkin Lymphoma|Relapsed or Refractory Anaplastic Large-cell Lymphoma
Interventions: DRUG: Brentuximab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fulvestrant and/or Anastrozole in Treating Postmenopausal Patients With Stage II-III Breast Cancer Undergoing Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Estrogen Receptor-positive Breast Cancer|HER2-negative Breast Cancer|Invasive Ductal Breast Carcinoma|Invasive Lobular Breast Carcinoma|Recurrent Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: DRUG: fulvestrant|DRUG: anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Family History Study on Cancer Risk
Status: ACTIVE_NOT_RECRUITING
Conditions: Lynch Syndrome|Colorectal Cancer|Breast Cancer|Ovarian Cancer|Family Characteristics|Genetic Predisposition
Interventions: OTHER: online cancer risk assessment|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Treatment of Bipolar Mania in Older Adults
Status: COMPLETED
Conditions: Bipolar Disorder|Mania
Interventions: DRUG: Lithium (LI)|DRUG: Divalproex (DV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Internet-based Program for Prevention and Early Intervention of Adolescent Depression
Status: COMPLETED
Conditions: Depressive Symptoms
Interventions: BEHAVIORAL: Take care of your mood (CUIDA TU ANIMO in Spanish)|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Single Fraction Intraoperative Radiotherapy
Status: COMPLETED
Conditions: Invasive Ductal and Invasive Lobular Breast Carcinoma|Stage 0 Breast Carcinoma|Stage I Breast Carcinoma|Stage II Breast Carcinoma
Interventions: PROCEDURE: Intraoperative Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erectile Dysfunction in Good Prognosis Prostate Cancer : Comparison Between Brachytherapy and Stereotactic Body Radiotherapy
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Radiation by brachytherapy|RADIATION: Radiation by SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-inflammatories and Adolescent Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Celecoxib 200mg|DRUG: Placebo oral capsule|DRUG: Minocycline 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Switching From the Preserved to the Preservative - Free Latanoprost - Timolol FC in Glaucoma Patients With OSD
Status: UNKNOWN
Conditions: Primary Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Switching the preserved prostaglandin analog-timolol FC to Fixalpost (preservative free prostaglandin analog-timolol FC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Risperidone Consta Reduce Relapse and Rehospitalization in Bipolar Disorder?
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Risperdal (risperidone) Consta|DRUG: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Adjuvant Chemotherapy on the Quality of Life of Patients Treated for Stage II / III Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Cancer|Chemotherapy Effect|Quality of Life
Interventions: OTHER: Self questionnaires of quality of life and living conditions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Inspiratory Muscle Training and COPD
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Test of Incremental Respiratory Endurance - IMT|DEVICE: Threshold - IMT|DEVICE: Sham IMT (Low resistence)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of ARGX-113 in Patients With Myasthenia Gravis Who Have Generalized Muscle Weakness
Status: COMPLETED
Conditions: Generalized Myasthenia Gravis
Interventions: BIOLOGICAL: ARGX-113|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Jaktinib in Participants With Severe Novel Coronavirus Pneumonia(COVID-19)
Status: WITHDRAWN
Conditions: COVID-19|Pneumonia
Interventions: DRUG: Jaktinib hydrochloride tablets|DRUG: Jaktinib hydrochloride tablets|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Persistent AF Catheter Ablation: Re-PVI vs. Re-PVI + Continuous Complex Activity Mapping and Ablation - AF-CAM
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Re-PVI only|PROCEDURE: Re-PVI + substrate ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of GanedenBC30 (Bacillus Coagulans GBI-30, 6086) on the Gut Microbiome in Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: GanedenBC30
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial of the C-Tb Skin Test, When Given Intradermally to Adult Patients Recently Diagnosed With Active Tuberculosis (TB)
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: C-Tb|BIOLOGICAL: 2 TU Tuberculin PPD RT 23 SSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Pentoxifylline as Add on Therapy in COVID19 Patients
Status: WITHDRAWN
Conditions: COVID
Interventions: DRUG: Pentoxifylline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cerclage for Twins With Short Cervical Length ≤ 15mm
Status: RECRUITING
Conditions: Twin Pregnancy With Antenatal Problem|Preterm Birth|Short Cervix
Interventions: PROCEDURE: Cervical cerclage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of an 8-week Vegan Diet on TMAO Levels and Post-challenge Glucose Levels in Individuals With Dysglycaemia
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Heart Diseases
Interventions: OTHER: Adoption of a vegan diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: BAY2328065 Single Dose Escalation, Safety and Tolerability, Pharmacokinetics, Relative Bioavailability, Food Effect
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: BAY2328065|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Enhancing the Effects of Adolescent Alcohol Treatment With Atomoxetine
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: Atomoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lithium Versus Paroxetine in Patients With Major Depression Who Have a Family History of Bipolar Disorder or Suicide
Status: TERMINATED
Conditions: Major Depressive Disorder
Interventions: DRUG: paroxetine|DRUG: lithium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Yogurt Containing BB12 in Subjects With GI Symptoms
Status: COMPLETED
Conditions: Pain
Interventions: DIETARY_SUPPLEMENT: Probiotic BB12 - Bifidobacterium lactis|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Haemodynamic Changes During Anaesthesia in the Prone Position, Evaluated Using Transoesophageal Ultrasound
Status: UNKNOWN
Conditions: Obesity|Spinal Surgery|Anaesthesia|Changes in Left and Right Ventricle Dimension|Changes in Bloodflow Across Cardiac Valves|Changes in Dimensions of Inferior Caval Dimension and Hepatic Venous Bloodflow|Changes i Myocardial Velocities|Changes in Diastolic Function
Interventions: OTHER: Change from supine to prone position
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Norepinephrine Infusion Different Doses in Cesarean Delivery
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: DRUG: norepinephrine infusion (0.025 mcg/Kg/min)|DRUG: norepinephrine infusion (0.050 mcg/Kg/min)|DRUG: norepinephrine infusion (0.075 mcg/Kg/min)|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Deep Friction Vs Stretching Techniques
Status: COMPLETED
Conditions: Deep Transverse Friction Massage
Interventions: OTHER: Deep transverse Friction Massage|OTHER: Dynamic stretching intervention|OTHER: Static stretching intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Surgical Technique on Post-operative Complications in Urgency Ostomy Confection
Status: COMPLETED
Conditions: Colostomy Stoma|Colostomy Complication|Obstruction Bowel|Surgical Complication|Surgical Procedure, Unspecified
Interventions: PROCEDURE: Intestinal ostomy confection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing the Efficacy of Bricanyl M2 and Bricanyl M3 at 0.5 and 1.5 mg Dose Levels, to Allow for a Switch From Bricanyl Turbuhaler M2 to Bricanyl Turbuhaler M3
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Terbutaline sulphate|DRUG: Terbutaline sulphate|DRUG: Placebo for terbutaline sulphate|DRUG: Placebo for terbutaline sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Investigate Efficacy and Safety With Oral AZD9833 Compared With Intramuscular Fulvestrant in Post-menopausal Women at Least 18 Years of Age With Advanced ER-positive HER2 Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced ER-Positive HER2-Negative Breast Cancer
Interventions: DRUG: AZD9833|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Safety, Tolerability and Activity of AZD5069 When Given as a Single Dose to Healthy Male and/or Female Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD5069|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of Regional Anesthesia in Hip Arthroscopy
Status: UNKNOWN
Conditions: Hip Injuries
Interventions: DRUG: Ropivacaine|OTHER: Normal Saline Sham Injection|PROCEDURE: General Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Treatment With Tiotropium Inhalation Capsules to Combivent Inhalation Aerosol in COPD Patients.
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: tiotropium|DRUG: Combivent (Ipratropium/Albuterol)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Impacts of Superselective Infarct-related Artery (IRA) Infusion of Tirofiban on Myocardial Reperfusion and Bleeding Complications in Acute Myocardial Infarction (AMI) Patients
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: PROCEDURE: administration of tirofiban by thrombus aspiration catheter in infarct-related artery|PROCEDURE: administration of tirofiban by guide catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Outcomes in Stable Renal Transplant Patients Switched fromTacrolimus to Envarsus XR™
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Transplant
Interventions: DRUG: Change from Prograf to Envarsus XR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Human Umbilical Cord Tissue-Derived Mesenchymal Stem Cells in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: Umbilical cord mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Applying a Small Procedure Prior to Injection/Vaccination Reduces Pain Experiences in Child Patients
Status: NOT_YET_RECRUITING
Conditions: Pediatric Pain
Interventions: OTHER: Possession of a customized placebo analgesic band-aid prior to vaccination or injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Acute Effect Comparisons of Manual Therapy Or Ankle Motion in Individuals Who Had Achilles Tendon Repair
Status: RECRUITING
Conditions: Achilles Tendon Rupture|Functional Performance
Interventions: OTHER: Compressive Myofascial Release|OTHER: Ankle mobilisation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of IDEC-152 in the Treatment of Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: IDEC-152
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Arsenic Trioxide in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Status: WITHDRAWN
Conditions: Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Recurrent Adult Acute Myeloid Leukemia
Interventions: DRUG: arsenic trioxide|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, Pharmacokinetic/Pharmacodynamic Characteristics, and Food Effect of HSG4112
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: HSG4112|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Iressa (ZD1839) Plus Anastrozole (Arimidex) in Patients With Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Peritoneal Carcinoma|Tubal Carcinoma
Interventions: DRUG: Iressa (ZD1839)|DRUG: Arimidex (Anastrozole)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eye Movement Desensitization and Reprocessing on Autoimmune Thyroiditis in Adults
Status: COMPLETED
Conditions: Hashimoto
Interventions: BEHAVIORAL: Eye Movement Desensitization and Reprocessing|OTHER: Placebo|DRUG: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Observational Single-center Study of the Relationship Between Arterial Hypertension and Hypervolemia Defined by Self-measurement of Impedancemetry in Kidney Transplant Patients With Transplantation Less Than 6 Months Old
Status: RECRUITING
Conditions: Kidney Transplant Patients
Interventions: OTHER: Measurement of systolic and diastolic blood pressure, impedancemetry, weight, creatinemia and Pro-BNP measurements
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Control Systems Engineering for Weight Loss Maintenance
Status: RECRUITING
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Intervention Targeting Stress and Emotion Regulation|BEHAVIORAL: Intervention Targeting Motivation and Self-efficacy for Weight Management|BEHAVIORAL: Intervention for Normalization of Eating|BEHAVIORAL: Intervention Targeting Physical Activity and Sleep
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of an Individually Adapted Lumbosacral Orthosis on Plantar Pressure and Balance
Status: ACTIVE_NOT_RECRUITING
Conditions: Orthosis|Low Back Pain, Postural
Interventions: OTHER: First Intervention|OTHER: Second Intervention|OTHER: Third Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Pilot Pharmacokinetic Study of Oral Testosterone Ester Formulations in Hypogonadal Men
Status: COMPLETED
Conditions: Hypogonadism
Interventions: DRUG: Testosterone undecanoate|DRUG: Testosterone enanthate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety of Two Medications to Treat Hepatitis C in People With Thalassemia (The HepC Study)
Status: COMPLETED
Conditions: Hepatitis C|Thalassemia
Interventions: DRUG: Peginterferon Alfa-2a and Ribavirin|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Dasatinib (50 mg Daily) as First-line Treatment for Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia
Interventions: DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II/III Trial to Evaluate the Efficacy and Safety of Surufatinib Combined With Camrelizumab, Nab-paclitaxel, and Gemcitabine in Metastatic Pancreatic Cancer
Status: RECRUITING
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Surufatinib Combined With Camrelizumab, Nab-paclitaxel, and Gemcitabine|DRUG: Nab-paclitaxel Plus Gemcitabine|DRUG: Surufatinib with Nab-paclitaxel, and Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Desmopressin on Blood Loss and the Quality of the Surgical Field During Endoscopic Sinus Surgery
Status: COMPLETED
Conditions: Patients Undergoing Endoscopic Sinus Surgery
Interventions: DRUG: Desmopressin|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety, Tolerability and Pharmacokinetics/Pharmacodynamics of Oral Doses of H008
Status: COMPLETED
Conditions: Erosive Esophagitis
Interventions: DRUG: H008|DRUG: H008 placebo|DRUG: Lansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Theatre in Adolescents With Chronic Medical Conditions (CMCs)
Status: WITHDRAWN
Conditions: Chronic Disease
Interventions: BEHAVIORAL: Intervention: Integrative Community Therapy-based Psychodrama|BEHAVIORAL: Control: Improvisational Theatre
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) in Ischaemic, Inflammatory and Takotsubo Cardiomyopathy (MEMORY)
Status: COMPLETED
Conditions: Myocarditis|Takotsubo Cardiomyopathy|Reversible Coronary Ischaemia
Interventions: DIAGNOSTIC_TEST: Cardiac MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of 100IR, 300IR, 500IR Sublingual House Dust Mite (HDM) Tablets in Allergic Rhinitis Environment Exposure Chamber Model
Status: COMPLETED
Conditions: House Dust Mites Allergic Rhinitis
Interventions: BIOLOGICAL: 100IR|BIOLOGICAL: 300IR|BIOLOGICAL: 500IR|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physiological Effects of Creatine Supplementation in Active Males
Status: COMPLETED
Conditions: Dietary Supplementation
Interventions: DIETARY_SUPPLEMENT: Creatine monohydrate|DIETARY_SUPPLEMENT: Creatine nitrate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Clorotekal and Bupivacaine for Short Obstetric Surgery
Status: SUSPENDED
Conditions: Anesthesia, Spinal
Interventions: DRUG: Chloroprocaine Injection [Clorotekal]|DRUG: Bupivacaine Hydrochloride 0.75% Injection Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outbreak of Hemolytic Uremic Syndrome Linked to Escherichia Coli of Serotype O104:H4
Status: COMPLETED
Conditions: Hemolytic-uremic Syndrome|Escherichia Coli Infections
Interventions: OTHER: HUS standard coverage care (including in ICU)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of AGN-195263 for the Treatment of Meibomian Gland Dysfunction
Status: COMPLETED
Conditions: Meibomian Gland Dysfunction
Interventions: DRUG: AGN-195263 0.1%|DRUG: AGN-195263 0.03%|DRUG: AGN-195263 0.01%|DRUG: AGN-195263 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Group-based Intervention for Club Patrons
Status: COMPLETED
Conditions: Drink Driving|Drink Too Much|Drinking, Binge|Drunk|Drug Use|Aggression|Aggression Sexual|Peer Group
Interventions: BEHAVIORAL: Three 0's|BEHAVIORAL: Fire Safety
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Barrett's Esophagus - 315 - 3 Way Cross Over
Status: COMPLETED
Conditions: Barrett's Esophagus
Interventions: DRUG: Esomeprazole|DRUG: Aspirin|DRUG: Rofecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Hepatitis C in Pakistan. Strategies to Avoid Resistance to Antiviral Drugs
Status: RECRUITING
Conditions: Hepatitis C, Chronic
Interventions: DIAGNOSTIC_TEST: HCV RNA (PCR)|DIAGNOSTIC_TEST: HCV Antibody test (Point of care)|DIAGNOSTIC_TEST: AST/ALT and platelets measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Propofol and Sevoflurane as Maintaining Anesthetics During General Anesthesia of Cesarean Section
Status: UNKNOWN
Conditions: Sevoflurane|Propofol|Cesarean Section
Interventions: DRUG: propofol|DRUG: sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Masitinib in Primary Progressive Multiple Sclerosis or Relapse-free Secondary Progressive Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: masitinib|DRUG: masitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inferior Alveolar Nerve Block for Intraoperative Analgesia for Maxillofacial Cancer Surgery - RCT
Status: COMPLETED
Conditions: Mandibular Neoplasms
Interventions: PROCEDURE: inferior alveolar nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Interventional Study Exploring the Microbiota Recolonization in SR-GvHD Patients Receiving MaaT013
Status: RECRUITING
Conditions: Intestinal GVHD|Steroid Refractory GVHD
Interventions: PROCEDURE: Blood and stool sample collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trial of Trametinib and Ponatinib in Patients With KRAS Mutant Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer|KRAS Gene Mutation
Interventions: DRUG: Trametinib 0.5 mg|DRUG: Trametinib 1 MG|DRUG: Trametinib 1.5 MG|DRUG: Trametinib 2 mg|DRUG: Ponatinib 15 MG|DRUG: Ponatinib 30 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pneumatic Tourniquet Application in Upper Extremity Surgeries
Status: COMPLETED
Conditions: Skin Wound|Complication of Surgical Procedure
Interventions: OTHER: Standard tourniquet pressure (250 mmHg)|OTHER: Limb occlusion pressure|OTHER: Cotton Pad|OTHER: Elastic stockinette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Systems Biology Guided Therapy for Breast Cancer Positive for Oestrogen Receptor After Aromatase Inhibitor and CDK Inhibition
Status: RECRUITING
Conditions: Breast Cancer|Estrogen Receptor-positive Breast Cancer|HER2-negative Breast Cancer
Interventions: DRUG: Drug determined by treating oncologist based on recommendation from systems biology analysis.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Radio-hybrid Prostate Specific Membrane Antigen (rhPSMA-7.3) (18F) in Healthy Volunteers and Subjects With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: rhPSMA-7.3 (18F) Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Acu-TENS and Acupressure on the Sleep Quality
Status: COMPLETED
Conditions: acuTENS|Sleep Quality|Insomnia|Acupressure
Interventions: DEVICE: Acu-TENS|OTHER: acupressure+SHP|OTHER: placebo stimulation+SHP|OTHER: sleep hygiene program(SHP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study to Evaluate Skin Cleansing With a Sodium Hypochlorite Wash
Status: WITHDRAWN
Conditions: Arterial Bypass Graft Surgery
Interventions: OTHER: Sodium Hypochlorite Cleanser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Osimertinib Plus Chemotherapy vs Osimertinib in EGFRm NSCLC With Persistence Week-3 ctDNA EGFRm After 1L Osimertinib
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Osimertinib|DRUG: Pemetrexed/Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety Study of Autologous TILs Therapy for Patients With Glioblastoma Multiforme.
Status: RECRUITING
Conditions: Glioblastoma Multiforme, Adult
Interventions: BIOLOGICAL: Tumor Infiltrating Lymphocytes (TIL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Different Membrane Applications in Vertical Ridge Augmentation
Status: COMPLETED
Conditions: Bone Regeneration|Dental Implants|Polytetrafluoroethylene
Interventions: PROCEDURE: Guided bone regeneration with a PTFE membrane|PROCEDURE: Guided bone regeneration with a PTFE+collagen membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: QLB and Radical Cystectomy, Postoperative Pain
Status: COMPLETED
Conditions: Postoperative Pain|Chronic Pain Post-Proceduraal|Nausea and Vomiting, Postoperative
Interventions: PROCEDURE: QLB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of QingReMoShen Granule to Treat Idiopathic Membranous Nephropathy
Status: COMPLETED
Conditions: Idiopathic Membranous Nephropathy
Interventions: DRUG: Losartan Tablets & QingReMoShen Granule|DRUG: Losartan Tablets & Placebo Granule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Support and Rehabilitation Protocol for Non Metastatic Breast Cancer Patients in Complete Remission After Chemotherapy
Status: TERMINATED
Conditions: Non Metastatic Breast Cancer
Interventions: BEHAVIORAL: dietaty education, physical training, physiotherapy and SPA cares
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma for Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: platelet rich plasma|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Medication for Improved Analgesia in Superficial Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Diclofenac and Atropine combination drug|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of the Effects of Erythritol on Endothelial Function in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Erythritol-containing beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE