pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Survey of Patient and Physician Awareness and Values to the Diagnosis and Treatment of Reduced Kidney Function (Chronic Kidney Disease) in Patients With High Blood Sugar Level (Type 2 Diabetes) (AWARE-CKD in T2D)
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Pevonedistat Combined With Decitabine and Cedazuridine in Adults With Higher-risk Myelodysplastic Syndromes
Status: WITHDRAWN
Conditions: Myelodysplastic Syndromes (MDS)
Interventions: DRUG: Pevonedistat|DRUG: Decitabine|DRUG: Cedazuridine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Therapy Plus Naltrexone for Alcoholism
Status: COMPLETED
Conditions: Alcoholism|Alcohol Dependence
Interventions: DRUG: naltrexone (Revia)|BEHAVIORAL: cognitive behavior therapy|BEHAVIORAL: motivational enhancement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Clozapine vs Olanzapine in Childhood-Onset Psychotic Disorders
Status: COMPLETED
Conditions: Childhood Schizophrenia|Psychotic Disorder|Schizophrenia
Interventions: DRUG: Olanzapine|DRUG: Clozapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy of Adjunctive Lithium Treatment for the Treatment of Psychotic Mania
Status: WITHDRAWN
Conditions: Bipolar I Disorder
Interventions: DRUG: Lithium treatment in combination with a SGA (Second Generation Antipsychotic)|DRUG: Placebo/Adjunctive SGA treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Radiotherapy in Patients With Pathological High-risk Bladder Cancer (GETUG-AFU 30)
Status: RECRUITING
Conditions: Patients With High-risk MIBC
Interventions: RADIATION: pelvic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Closed-Loop Control System for Administering Patient-Specific Anesthesia
Status: COMPLETED
Conditions: Anesthesia, General
Interventions: DEVICE: ReinLoop control software for patient-specific induction and maintenance of anesthesia|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose:
Clinical trial: Serologic Response to Pneumococcal Vaccination Among Esophageal Cancer Patients With High Grade Lymphopenia After Chemoradiation
Status: RECRUITING
Conditions: Pneumococcal Vaccine|Esophageal Cancer|Lymphopenia|Chemoradiation
Interventions: BIOLOGICAL: Pneumonia vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation
Status: COMPLETED
Conditions: Acute Leukemias of Ambiguous Lineage|Bacterial Infection|Diarrhea|Fungal Infection|Musculoskeletal Complications|Neutropenia|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies
Interventions: DRUG: levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mycophenolate Mofetil and Tacrolimus Versus Tacrolimus for the Treatment of Idiopathic Membranous Glomerulonephritis
Status: COMPLETED
Conditions: Glomerulonephritis, Membranous
Interventions: DRUG: tacrolimus|DRUG: tacrolimus and mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Definition Transcranial Direct Current Stimulation (HD-tDCS) in Patients With Mild Cognitive Impairment
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: HD-tDCS treatment|DEVICE: sham (placebo) HD-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regenerative Endodontic Treatment of Mature Necrotic Teeth With Apical Periodontitis
Status: COMPLETED
Conditions: Necrotic Pulp|Apical Periodontitis
Interventions: OTHER: Biodentine|OTHER: White MTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Venlafaxine on Chronic Neuropathic Pain Following Spinal Cord Injury
Status: COMPLETED
Conditions: Neuropathic Pain|Pain|Spinal Cord Injuries
Interventions: DRUG: Venalafaxine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Frog Leg Technique in Management of Low Back Pain Due to Lumbar Lordosis
Status: COMPLETED
Conditions: Low Back Pain, Postural
Interventions: OTHER: Frog Leg Exercise|OTHER: Electrotherapy(Transcutaneous Electrical Nerve Stimulator)|OTHER: Exercise Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Intrauterine Biological Barrier on Postoperative Adhesion After Hysteroscopic Adhesiolysis
Status: RECRUITING
Conditions: Intrauterine Adhesion
Interventions: DEVICE: Intrauterine Biological Barrier|DEVICE: Intrauterine Adhesion Barrier Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Probiotics on Infections in Toddlers
Status: COMPLETED
Conditions: Diarrhoea|Respiratory Diseases
Interventions: DIETARY_SUPPLEMENT: probiotics|DIETARY_SUPPLEMENT: probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of 188-0551 Solution Versus Vehicle Solution in Subjects With Plaque Psoriasis (Study 203)
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: 188-0551 Solution|DRUG: Vehicle Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pirtobrutinib With Rituximab for the Treatment of Newly Diagnosed Marginal Zone Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Marginal Zone Lymphoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Pirtobrutinib|PROCEDURE: Positron Emission Tomography|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Remotely-Delivered Yoga Intervention on Cognitive Function in Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Cancer|Breast Cancer Stage I|Breast Cancer Stage II|Breast Cancer Stage III
Interventions: BEHAVIORAL: Yoga Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinic-based ART Diagnostic Evaluation
Status: COMPLETED
Conditions: Acquired Immunodeficiency Syndrome|HIV Infection|RNA Virus Infections|Virus Diseases
Interventions: OTHER: HIV-1 viral load testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Immunological and Clinical Responses to Zinc in Children With Diarrhoea
Status: COMPLETED
Conditions: Diarrhoea
Interventions: DRUG: Zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Preliminary Efficacy of MOR103 in Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: MOR103|DRUG: MOR103|DRUG: MOR103
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Innate Inflammation in New Onset Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes|type1diabetes|Type 1 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Lactiplantibacillus plantarum|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: CPR Training: Video Self-Instruction Kit or Video-Only
Status: COMPLETED
Conditions: Cardiovascular Risk Factors|Coronary Disease|Cardiac Arrest
Interventions: OTHER: CPR Training using the Family and Friends CPR Anytime Video Self Instruction|OTHER: Implementation of a Hospital-based CPR Training Model|OTHER: Follow-up prompting to encourage skill retention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Glucose-insulin-potassium Solution on Myocardial Protection During Off-pump Coronary Bypass Surgery in Patients With Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: GIK solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Remineralization of Early Carious Lesion Using Natural Agents Versus Bioadhesive Polymers
Status: COMPLETED
Conditions: Dental Caries
Interventions: OTHER: Clove water extract|OTHER: Carbopol|OTHER: Carboxymethyle cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Food Preferences on the Occurrence of Undernutrition in Treated Patients for Bronchopulmonary Carcinoma Non-small Cell Stage IV
Status: RECRUITING
Conditions: Non-small Cell Bronchopulmonary Carcinoma at Stage IV and Benefiting From First-line Treatment According to Current French Recommendations
Interventions: OTHER: Test Leeds Food Preference Questionnaire (LFQP-France)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparative Effects of Mild and Moderate Aerobic Exercises on BP, VO2 and HR in Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: OTHER: mild aerobic exercise|OTHER: moderate aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Subthreshold Laser Treatment for Reticular Pseudodrusen and Geographic Atrophy Secondary to AMD
Status: COMPLETED
Conditions: Age-Related Macular Degeneration|Geographic Atrophy|Reticular Pseudodrusen
Interventions: PROCEDURE: Subthreshold 577 nm yellow wavelength laser photo-coagulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Surveillance of VaxigripTetra® and Efluelda® Influenza Vaccines in Europe During the Influenza Season 2023/24
Status: COMPLETED
Conditions: Influenza Immunization (Healthy Volunteers)
Interventions: BIOLOGICAL: Quadrivalent Influenza Vaccine|BIOLOGICAL: High-Dose Quadrivalent Influenza Vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Outcome of Proximal Humerus Fractures :Anatomic Neck Fractures vs Surgical Neck Fractures
Status: COMPLETED
Conditions: Humeral Fracture, Proximal|Internal Fixation; Complications, Mechanical, Bones of Limb
Interventions: PROCEDURE: Locking plates were used for proximal humeral fractures.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Pharmacokinetic and Pharmacodynamic Effects of Delta-8 and Delta-9 THC
Status: RECRUITING
Conditions: Behavioral Pharmacology of Cannabis
Interventions: DRUG: Oral Delta-8-THC Cannabis|DRUG: Oral Delta-9-THC Cannabis|DRUG: Oral Placebo|DRUG: Vaporized Delta-8-THC Cannabis|DRUG: Vaporized Delta-9-THC Cannabis|DRUG: Vaporized Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Probiotic Supplementation as Prophylactic for Group B β-hemolytic Streptococcus (GBS) Infection
Status: COMPLETED
Conditions: Genitourinary; Infection, Complicating Pregnancy
Interventions: DIETARY_SUPPLEMENT: Probiotic iNatal®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing Effectiveness of Oral Misoprostal for Cervical Priming in Hysteroscopy
Status: COMPLETED
Conditions: Abnormal Uterine Bleeding|Chronic Pelvic Pain|Infertility, Female
Interventions: DRUG: Misoprostol 200Mcg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Psychological Intervention and Physiotherapy With Medication Improves CRPS Patients Outcome
Status: COMPLETED
Conditions: CRPS
Interventions: DRUG: Morphine, memantine|BEHAVIORAL: Psychological intervention|OTHER: Physiotherapy intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coalition for a Healthier Community-Utah Women and Girls - Phase II (UWAG-II)
Status: COMPLETED
Conditions: Obesity|Physical Activity|Diabetes
Interventions: BEHAVIORAL: High Intensity Arm (Intervention)|BEHAVIORAL: Low Intensity Arm (Comparison)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase II Trial of Cabozantinib With Patients With Refractory GCTs
Status: RECRUITING
Conditions: Germ Cell Tumor|Seminoma|Non-seminomatous Germ Cell Tumor|Ovarian Germ Cell Tumor
Interventions: DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pregabalin for the Treatment and Prevention of Spinal Cord Injury Neuropathic Pain
Status: UNKNOWN
Conditions: Neuropathic Pain|Spinal Cord Injuries
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cabozantinib S-Malate or Lenvatinib Mesylate on Weight and Body Composition in Patients With Metastatic Endocrine Cancer
Status: COMPLETED
Conditions: Differentiated Thyroid Gland Carcinoma|Malignant Adrenal Gland Pheochromocytoma|Malignant Paraganglioma|Thyroid Gland Medullary Carcinoma
Interventions: PROCEDURE: Computed Tomography|PROCEDURE: Dual X-ray Absorptiometry|PROCEDURE: Physical Examination|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Cabozantinib|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of Epitope Peptide To Treat HLA-A*24 Disease Controlled Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: HLA-A*2402restricted URLC10, CDCA1, and KIF20A peptides with adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Wavelengths of Repeated Low-Level Light Therapy on Choroidal and Retinal Blood Flow Among Adults
Status: NOT_YET_RECRUITING
Conditions: Choroid|Retina
Interventions: DEVICE: repeated low level light device (Eyerising [Suzhou Xuanjia Optoelectronics Technology)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of the AFGen1 Device Over a 7-day Period
Status: COMPLETED
Conditions: Atrial Fibrillation|Afib|Irregular Heart Beat|Arrhythmias, Cardiac|Arrhythmia Atrial|Arrhythmias Paroxysmal|Paroxysmal Atrial Fibrillation
Interventions: DEVICE: AFGen1 Device Wear Test|DEVICE: AFGen 1 Device Single Use
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Lung Deposition Rate and Distribution Pattern of Tiotropium Via HandiHalerTM in Healthy Subjects and Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: 99mTc-radiolabelled tiotropium|DRUG: non-radiolabelled tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Star-Close Versus Angio-Seal for Femoral Artery Hemostasis
Status: WITHDRAWN
Conditions: Percutaneous Intervention Via Femoral Artery
Interventions: DEVICE: StarClose®|DEVICE: AngioSeal®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Stellate Ganglion Block as Novel Treatment for Heart Failure Patients
Status: RECRUITING
Conditions: Stellate Ganglion Block
Interventions: PROCEDURE: Stellate Ganglion Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test if TEV-50717 is Effective in Relieving Tics Associated With Tourette Syndrome (TS)
Status: COMPLETED
Conditions: Tourette Syndrome
Interventions: DRUG: TEV-50717|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cell-Mediated Immunity Based Primary Prophylaxis for CMV Infection in Organ Transplant Recipients
Status: COMPLETED
Conditions: Cytomegalovirus Viraemia
Interventions: DEVICE: Quantiferon-CMV assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Oblique Subcostal, Posterior or Dual Transversus Abdominis Plane Block in Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy|Cholelithiasis|Postoperative Analgesia
Interventions: PROCEDURE: unilateral ultrasound-guided oblique subcostal TAP block with %0.5 Bupivacaine 10ml + %1 Prilocaine 10ml + %0.9 NaCl 10ml|PROCEDURE: unilateral ultrasound-guided oblique subcostal TAP block with %0.9 NaCl 30ml|PROCEDURE: unilateral ultrasound-guided posterior TAP block with %0.5 Bupivacaine 10ml + %1 Prilocaine 10ml + %0.9 NaCl 10ml|PROCEDURE: unilateral ultrasound-guided posterior TAP block with %0.9 NaCl 30ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Application of Curcumin Orabase in Oral Submucous Fibrosis (OSMF)
Status: UNKNOWN
Conditions: Oral Submucous Fibrosis
Interventions: DRUG: Curcumin Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Tissue Samples From Young Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: DNA methylation analysis|GENETIC: gene expression analysis|GENETIC: microarray analysis|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Physical Therapy Exercise Program and Low-Level Laser Therapy on the Treatment of Cervicogenic Somatosensory Tinnitus
Status: COMPLETED
Conditions: Tinnitus, Subjective
Interventions: OTHER: Exercise Therapy program added to laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Selective Internal Radiation Therapy (SIRT) Versus Sorafenib in Locally Advanced Hepatocellular Carcinoma (HCC)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: SIR-Spheres|DRUG: Sorafenib tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving End-of-life Care by Continuing Medical Education and Electronic Decision Making Support for General Practitioners
Status: WITHDRAWN
Conditions: Chronic Obstructive Pulmonary Disease|Metastatic Cancer
Interventions: OTHER: continuing medical education and electronic decision support|OTHER: education and electronic support
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: On-treatment PLAtelet Reactivity-guided Therapy Modification FOR ST-segment Elevation Myocardial Infarction
Status: TERMINATED
Conditions: Acute ST-elevation Myocardial Infarction
Interventions: DRUG: Antiplatelet Regimen Modification (aspirin or ticagrelor)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of Red Blood Cell Integrity and Efficiency of Recovery Using a Novel Surgical Sponge-Blood Recovery Device (ProCell): Delayed Impact
Status: RECRUITING
Conditions: Blood Recovery
Interventions: PROCEDURE: Hand Wrung|DEVICE: ProCell Wrung
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Secretin Enhanced MRCP for Evaluation of the Known or Suspected Intraductal Papillary Mucinous Neoplasms of the Pancreas
Status: TERMINATED
Conditions: Intraductal Papillary Mucinous Neoplasms
Interventions: DRUG: RG1068 (Synthetic Human Secretin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Health Communication to Influence COVID-19 Vaccination Intent and Message Propagation
Status: COMPLETED
Conditions: COVID-19|Respiratory Disease|Vaccine Refusal|Infectious Disease|Coronavirus Infections|Behavior, Health|Pneumonia|Respiratory Tract Infections|Lung Diseases|Pneumonia, Viral
Interventions: BEHAVIORAL: Health message exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Influence of Pharmacogenetic Factors, Paroxetine and Clarithromycin on Pharmacokinetics of Clomiphene
Status: COMPLETED
Conditions: Anovulation|Disorder Due Cytochrome P450 CYP2D6 Variant|Cytochrome P450 CYP3A Enzyme Deficiency
Interventions: DRUG: Clomiphene|DRUG: clomiphene and paroxetine|DRUG: clomiphene and clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Study of EBV-TCR-T Cells for EBV Infection After Allogenic HSCT
Status: RECRUITING
Conditions: EBV Infection After Allogenic HSCT
Interventions: BIOLOGICAL: EBV-TCR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Melphalan Flufenamide (Melflufen) + Dex With Bortezomib or Daratumumab in Patients With RRMM
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Melphalan flufenamide (Melflufen)|DRUG: Dexamethasone|DRUG: Bortezomib|DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating HIV-1 Neutralization Antibody Breadth in Response to HIV gp120 Protein Vaccine in HIV-uninfected Adults With Quiescent Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: HIV Infections|Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: AIDSVAX® B/E
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial of Folic Acid Effect on Hcy and cIMT After Kidney Tx
Status: TERMINATED
Conditions: Kidney Transplantation
Interventions: DRUG: Folic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: An Open Trial to Assess the Tolerability of AVANZ® Salsola Immunotherapy
Status: COMPLETED
Conditions: Allergic Rhinoconjunctivitis Due to Salsola Kali Pollen
Interventions: BIOLOGICAL: AVANZ Salsola
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Development and Evaluation of Clinical Pharmacy Services in Respiratory Diseases
Status: COMPLETED
Conditions: Pneumonia|COPD Asthma|COPD Exacerbation
Interventions: BEHAVIORAL: Intervention groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Testing Brief Personalized Feedback Integrating Lab-based Alcohol Cue Information
Status: COMPLETED
Conditions: Alcohol Consumption
Interventions: BEHAVIORAL: Lab-based Cue Reactivity Personalized Feedback Intervention (PFI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster (HZ/su) Vaccine in Adults With Solid Tumours Receiving Chemotherapy
Status: COMPLETED
Conditions: Herpes Zoster|Herpes Zoster Vaccine
Interventions: BIOLOGICAL: GSK 1437173A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pulsed Paclitaxel And Daily Thoracic Radiotherapy For Inoperable (Stage I/II) Or Unresectable Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Paclitaxel|PROCEDURE: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CBD, Nutrient Metabolism and Energy Intake
Status: ACTIVE_NOT_RECRUITING
Conditions: Glucose Metabolism Disorders (Including Diabetes Mellitus)|Lipid Metabolism Disorders|Appetitive Behavior
Interventions: DIETARY_SUPPLEMENT: Acute oral CBD supplementation|DIETARY_SUPPLEMENT: Acute oral placebo supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Transnasal Induction of Normothermia in Febrile Stroke Patients
Status: COMPLETED
Conditions: Stroke, Ischemic|Stroke Hemorrhagic|Fever|Seizures|Metabolic Encephalopathy
Interventions: DEVICE: Transnasal Thermal Regulating Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Minoxidil Lotion Versus Combined Minoxidil and Finasteride Lotion to Treat Male Pattern Hair Loss
Status: COMPLETED
Conditions: Androgenetic Alopecia
Interventions: DRUG: 3%Minoxidil lotion|DRUG: 3% Minoxidil with 0.1% Finasteride lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Jaktinib and Azacitidine In Treating Patients With MDS With MF or MDS/MPN With MF.
Status: TERMINATED
Conditions: Myelodysplastic Syndromes|Myeloproliferative Neoplasms|Myelofibrosis
Interventions: DRUG: Jaktinib|DRUG: azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amygdala Neurofeedback for Depression - Large Scale Clinical Trial
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Amygdala real-time fMRI neurofeedback|BEHAVIORAL: Sham feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of a FDC Tablet of Linagliptin/Metformin (2.5mg/1000mg) Extended Release in Healthy Subjects.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Linagliptin|DRUG: Metformin|DRUG: Linagliptin/Metformin FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Trametinib in Combination With Docetaxel in Japanese Subjects With Non-small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Lung Cancer, Non-Small Cell
Interventions: DRUG: Trametinib|DRUG: Docetaxel|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lymphovenous Bypass Procedure Before Underarm Lymph Node Surgery in Preventing Lymphedema in Patients With Inflammatory or Locally Advanced Non-inflammatory Breast Cancer or Melanoma
Status: RECRUITING
Conditions: Anatomic Stage III Breast Cancer AJCC v8|Breast Inflammatory Carcinoma|Locally Advanced Breast Carcinoma|Melanoma
Interventions: DRUG: Indocyanine Green|PROCEDURE: Lymphangiography|PROCEDURE: Lymphovenous Bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: High-density Mapping-guided bOx Isolation and subsTrate Ablation
Status: UNKNOWN
Conditions: Atrial Fibrillation|Atrial Remodeling
Interventions: PROCEDURE: CPVI|PROCEDURE: CPVI+BOX|PROCEDURE: CPVI+BOX+SUB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of AVI-5126 When Used on Vein Grafts Before Use in Heart by-Pass Graft Surgery (CABG)
Status: TERMINATED
Conditions: Cardiovascular Disease|Coronary Artery Bypass
Interventions: DRUG: AVI-5126
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of a Two Ready-to-use Supplementary Foods of Differing Protein Quality for the Treatment of MAM.
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: C-RUSF|DIETARY_SUPPLEMENT: HIPRO RUSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: tACS Treatment for Cognitive Impairments in Methamphetamine Addicts
Status: RECRUITING
Conditions: Methamphetamine Abuse
Interventions: DEVICE: Theta treatment group|DEVICE: Alpha active control group|DEVICE: Sham control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antidepressant Effects of the Glycine Receptor Antagonist AV-101 (4-chlorokynurenine) in Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depression
Interventions: DRUG: AV 101 (4-Chlorokynurenine)|OTHER: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability Evaluation of a Topical MD Based on SHBF in Management of Radiodermatitis.
Status: COMPLETED
Conditions: Radiodermatitis|Dermatitis, Radiation-Induced
Interventions: DEVICE: DermoRelizema cream|DEVICE: Dexeryl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reactogenicity, Immunogenicity and Inflammatory Response by New COVID-19 Vaccine Platforms
Status: UNKNOWN
Conditions: COVID-19 Vaccination|Inflammation|Vaccine Immune Response|Vaccine Adverse Reaction
Interventions: BIOLOGICAL: either BNT162b2 or ChAdOx1 vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Tumor Necrosis Factor (TNF)-Alpha Antagonism in Patients With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome X
Interventions: DRUG: Etanercept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Highlanders With High Altitude Pulmonary Hypertension (HAPH), Pulmonary Arterial Pressure (PAP) Assessed at 3200m With and Without Supplemental Oxygen Therapy (SOT)
Status: NOT_YET_RECRUITING
Conditions: High Altitude Pulmonary Hypertension
Interventions: OTHER: Echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Chuna Manipulation Therapy on Gait in Patients With Lumbar Disc Herniation
Status: WITHDRAWN
Conditions: Lumbar Disc Herniation|Gait Analysis|Manual Therapy
Interventions: PROCEDURE: Chuna manipulation|DRUG: Herbal medicine|PROCEDURE: Bee venom pharmacopuncture|PROCEDURE: Pharmacopuncture|PROCEDURE: Acupuncture|PROCEDURE: Electroacupuncture|PROCEDURE: Cupping|OTHER: Other intervention(s)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Oral Oteseconazole for the Treatment of Patients With Recurrent Vaginal Candidiasis (Yeast Infection)
Status: COMPLETED
Conditions: Recurrent Vulvovaginal Candidiasis
Interventions: DRUG: Oteseconazole (VT-1161)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MK8245 (8245-004)(COMPLETED)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: MK8245|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential and Maintenance Icotinib Plus Chemotherapy Versus Icotinib Maintenance After Chemotherapy in Advanced NSCLC
Status: UNKNOWN
Conditions: EGFR Positive Non-small Cell Lung Cancer|Adenocarcinoma
Interventions: DRUG: Sequential and maintenance icotinib|DRUG: Maintenance icotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Imaging Study of 64Cu-SARTATE Using Positron Emission Tomography in Patients With Neuroendocrine Tumours
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: 64Cu-SARTATE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: OPtimizing Technology to Improve Medication Adherence and BP Control (OPTIMA-BP)
Status: RECRUITING
Conditions: Hypertension|Self-Management|Technology|Quality of Life
Interventions: BEHAVIORAL: OPTIMA-BP Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pioglitazone vs. Insulin Glargine in the Treatment of Secondary Drug Failure in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Secondary Drug Failure
Interventions: DRUG: pioglitazone|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Trastuzumab Emtansine (T-DM1) in Combination With Docetaxel, and Potentially Pertuzumab, in Participants With Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: Pertuzumab|DRUG: Trastuzumab emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fostering Healthy Futures Efficacy Trial for Preadolescent Youth in Foster Care
Status: COMPLETED
Conditions: Child Abuse
Interventions: OTHER: Assessment|BEHAVIORAL: Fostering Healthy Futures (FHF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study on the Efficacy and Safety of PEG-rhG-CSF in Preventing Neutropenia During Concurrent Chemoradiotherapy of Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DRUG: PEG-rhG-CSF|DRUG: rhG-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study on Plantar Pressure Distribution, Gait Balance and Lower Back Pain in Pregnant Women
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: 3D arch pad design Insole group|OTHER: flat Insole group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Metaverse Space-based Exercise Video Distribution in Young Adults
Status: COMPLETED
Conditions: Healthy
Interventions: BEHAVIORAL: Exercise video distribution of Metaverse|BEHAVIORAL: Exercise video distribution of YouTube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of the Consumption of a Fermented Dairy Product Enriched With Plant Sterols
Status: COMPLETED
Conditions: Mild Hypercholesterolemic Subjects
Interventions: OTHER: 1- low-fat dairy fermented product (drinkable) enriched with plant sterols-esters (1,6g /day equivalent as free sterols).|OTHER: 2- low-fat dairy fermented product (drinkable) enriched with experimental plant sterols-esters (1,6g /day equivalent as free sterols).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Biomarker Predictors of Memantine Sensitivity in Patients With Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: Memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Performance and Safety of the Medical Device Janesse in the Treatment of Facial Dermal Tissue Defects
Status: COMPLETED
Conditions: Cicatrix|Lipodystrophy|Plaque
Interventions: DEVICE: Janesse
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Nodular Basal Cell Carcinoma (BCC) With Imiquimod 5% Cream After Curettage
Status: COMPLETED
Conditions: Basal Cell Carcinoma
Interventions: DRUG: imiquimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab for Metastatic NSCLC Patients Expressing PD-L1 Who Have Their Own PDX
Status: RECRUITING
Conditions: Metastatic Non-Small Cell Lung Carcinoma
Interventions: DRUG: Pembrolizumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test How Different Doses of BI 1703880 in Combination With Ezabenlimab Are Tolerated in People With Different Types of Advanced Cancer (Solid Tumours)
Status: RECRUITING
Conditions: Solid Tumors
Interventions: DRUG: BI 1703880|DRUG: Ezabenlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Sedentary Time in Patients With Cardiovascular Disease
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Sedentary Behavior|Physical Activity
Interventions: BEHAVIORAL: Sit Less Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Post-op Crowd Sourcing Health Data Via Text-messaging
Status: COMPLETED
Conditions: Orthopedic Surgery|Opioid Use|Acute Injuries Knee|Neurosurgery|Surgery
Interventions: BEHAVIORAL: Observation|BEHAVIORAL: Text to online survey|BEHAVIORAL: Bi-directional text script
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Genes and the Environment in Patients With Endometrial Cancer in the East Anglia, Oxford, Trent, or West Midlands Regions of the United Kingdom
Status: UNKNOWN
Conditions: Endometrial Cancer
Interventions: GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Escalating Single Doses of TAK-935
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-935|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strategy + RehaCom for Memory Rehabilitation in Traumatic Brain Injury (TBI)
Status: UNKNOWN
Conditions: Traumatic Brain Injury With Loss of Consciousness
Interventions: DEVICE: RehaCom (software)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Combination Therapy With Alpha-1 Blocker (Bunazosin or Doxazosin) in the Treatment of Patients With Mild to Moderate Essential Hypertension
Status: COMPLETED
Conditions: High Blood Pressure
Interventions: DRUG: Bunazosin|DRUG: Doxazosin|DRUG: Valsartin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Benefits of Deep Neuromuscular Block and Sugammadex in Laparoscopic Colorectal Surgery
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Deep neuromuscular block using rocuronium and reversal with suggamadex|DRUG: Moderate neuromuscular block using rocuronium and reversal with suggamadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Sacral Fracture Fusion/Fixation for Rapid Rehabilitation
Status: ACTIVE_NOT_RECRUITING
Conditions: Fracture;Pelvis|Sacral Fracture|Sacroiliac; Fusion|Fragility Fracture|Insufficiency Fractures|Osteoporosis
Interventions: DEVICE: Surgical Intervention|OTHER: Non-Surgical Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safe Study of Routine Closure of Mesenteric Defects Versus Non-closure After Radical Gastrectomy
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: PROCEDURE: Closure of the mesenteric defects|PROCEDURE: Non-closure of the mesenteric defects
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Orathecin + Gemcitabine Versus Placebo + Gemcitabine in Chemonaive Non-Resectable Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: Rubitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Cognitive Therapy (Inference-based-therapy) for the Treatment of Obsessional Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: BEHAVIORAL: Cognitive behavior therapy|BEHAVIORAL: Mindfulness-based stress reduction|BEHAVIORAL: Inference-based therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: Farletuzumab ecteribulin|DRUG: Prednisone|DRUG: Prednisolone|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Painful Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathy, Painful
Interventions: DRUG: Duloxetine|DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Ascending Dose Study Assessing the Safety, Tolerability, PK and PD of MYK-491
Status: COMPLETED
Conditions: Dilated Cardiomyopathy
Interventions: DRUG: MYK-491 or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT