pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Lung Function Changes of Induced Asthma Children Treated With Inhaled MgSO4
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Magnesium Sulfate|DRUG: magnesium sulfate & albuterol|DRUG: Albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: B-type Natriuretic Peptide (BNP)-Guided Diagnostic Strategy in Intensive Care Unit (ICU) Patients With Respiratory Failure
Status: COMPLETED
Conditions: Respiratory Insufficiency
Interventions: PROCEDURE: BNP guided diagnostics and initial therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Adebrelimab and Fruquintinib Combined With Paclitaxel/Albumin Paclitaxel for Advanced Gastric Cancer After PD-1 Antibody Failed
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Adebrelimab，Fruquintinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Gemcitabine With TheraSphere® (Yttrium-90)in Patients With Hepatic Tumors of Pancreatobiliary Origin
Status: TERMINATED
Conditions: Pancreatic Neoplasms|Cholangiocarcinoma
Interventions: DRUG: Gemcitabine with TheraSphere
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Liposomal Doxorubicin Used Alone or in Combination With Bleomycin Plus Vincristine in the Treatment of Kaposi's Sarcoma in Patients With AIDS
Status: COMPLETED
Conditions: Sarcoma, Kaposi|HIV Infections
Interventions: DRUG: Doxorubicin hydrochloride (liposomal)|DRUG: Filgrastim|DRUG: Bleomycin sulfate|DRUG: Vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: IdeS in Asymptomatic Antibody-Mediated Thrombotic Thrombocytopenic Purpura (TTP) Patients
Status: TERMINATED
Conditions: Purpura, Thrombotic Thrombocytopenic
Interventions: BIOLOGICAL: IdeS (0.25 mg/kg)|BIOLOGICAL: IdeS (0.50 mg/kg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UTB-VBN-EBUS With or Without Fluoroscopy for the Diagnosis of PPLs
Status: COMPLETED
Conditions: Lung Cancer
Interventions: PROCEDURE: VBN|PROCEDURE: EBUS|PROCEDURE: X-ray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A STudy of Upper Arm Rehabilitation in Stroke Survivors- ASTAR
Status: UNKNOWN
Conditions: Stroke|Upper Limb Injury|Rehabilitation
Interventions: OTHER: Action for Rehabilitation for Neurological Injury (ARNI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A TAK-831-1001, Single and Multiple Rising Dose Study in Healthy Participants
Status: TERMINATED
Conditions: Schizophrenia, Cerebellar Ataxia
Interventions: DRUG: TAK-831 Oral Suspension|DRUG: TAK-831 Placebo|DRUG: TAK-831 Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study of Irinotecan and AZD1775, a Selective Wee 1 Inhibitor, in RAS or BRAF Mutated, Second-line Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: AZD1775|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficiency of Home Based Dual Task Training in Parkinson Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: PROCEDURE: Static, dynamic and functional balance exercises|PROCEDURE: Static, dynamic and functional balance exercises with dual task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: T-regulatory Cell Depletion With E7777 Combined With Pembrolizumab in Recurrent or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Epithelial Ovarian Cancer
Interventions: DRUG: Pembrolizumab|DRUG: E7777
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotine Withdrawal and Reward Processing
Status: COMPLETED
Conditions: Cigarette Smoking|Nicotine Dependence|Nicotine Withdrawal
Interventions: OTHER: Smoking Abstinence|OTHER: Ad Lib Smoking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A 12-Week Safety and Pharmacodynamic Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease
Status: COMPLETED
Conditions: Fabry Disease
Interventions: DRUG: migalastat HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: pArtiaL zonA pelluciDa Removal by assisteD hatchINg of Blastocysts
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: Laser assisted hatching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of AQX-1125 in Subjects With Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Status: TERMINATED
Conditions: Chronic Prostatitis|Chronic Pelvic Pain Syndrome
Interventions: DRUG: AQX-1125 200 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind Clinical Investigation to Evaluate the Use of the Relievion™ Device in Treating Migraine.
Status: TERMINATED
Conditions: Migraine
Interventions: DEVICE: Relievion Device- Treatment Stimulation|DEVICE: Relievion Device- Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Pulse Amplitude Seizure Therapy (LAP-ST Study)
Status: COMPLETED
Conditions: Mood Disorders|Schizophrenia Spectrum and Other Psychotic Disorders
Interventions: DEVICE: Mecta spectrum 5000Q device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy and Tolerability of Hemopatch After Hepatic Resection
Status: UNKNOWN
Conditions: Hepatectomy|Cancer, Metastatic|Hemostasis
Interventions: DEVICE: Hemopatch|PROCEDURE: Common Surgical Techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Group-based Stabilization and Skill Training for Patients With Lasting Posttraumatic Reactions in Mental Health Care
Status: RECRUITING
Conditions: Stress Disorders, Post-Traumatic|Mental Disorders|Trauma and Stressor Related Disorders
Interventions: BEHAVIORAL: Group-based stabilization and skill training in addition to individual treatment|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label, 48-Week Extension Study of Elvucitabine in Combination With Background Antiretroviral Therapy (ART) for Participants Who Have Completed Study ACH443-014A
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV)-1 Infection
Interventions: DRUG: Elvucitabine|DRUG: Lamivudine|DRUG: Emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib Trial of a Maintenance Multipeptide Vaccine (S-588210) in Patients With Unresectable Malignant Pleural Mesothelioma Without Progression After First-Line Chemotherapy
Status: WITHDRAWN
Conditions: Malignant Pleural Mesothelioma (MPM)
Interventions: BIOLOGICAL: Multipeptide vaccine S-588210
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy Versus no Intervention in Adult Patients With Hepatocellular Carcinoma Not Eligible for Transarterial Chemoembolization or Ablation Prior to Liver Transplant (RADBRI)
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: Stereotactic body radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Carbetocin to Decrease Blood Loss During Hysteroscopic Myomectomy
Status: COMPLETED
Conditions: Myoma;Uterus
Interventions: DRUG: Carbetocin|DRUG: Sodium chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Transrectal MRI-Guided Biopsy in Identifying Cancer in Patients With Suspected Prostate Cancer
Status: TERMINATED
Conditions: Health Status Unknown|Prostate Carcinoma
Interventions: PROCEDURE: 3 Tesla Magnetic Resonance Imaging|RADIATION: Gadodiamide|PROCEDURE: Multiparametric Magnetic Resonance Imaging|PROCEDURE: Transrectal Biopsy|PROCEDURE: Ultrasound-Guided Prostate Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Open-label Study of a Gene Therapy Product (Vebeglogene Autotemcel) in Transfusion Dependent Beta-Thalassemia
Status: RECRUITING
Conditions: Beta-Thalassemia
Interventions: DRUG: Vebeglogene autotemcel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Absorption, Metabolism, and Excretion of [14C]-AMG 510 Following a Single Oral Dose in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: AMG 510
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Low and High Dose of Dexmedethomidine in Pituitary Tumor Removal by Transphenoid Approach
Status: UNKNOWN
Conditions: Pituitary Tumor
Interventions: DRUG: high dose dexmedethomidine|DRUG: low dose dexmedethomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atrial Fibrillation (AF) Clinic to Improve the Treatment of Patients With Atrial Fibrillation.
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: OTHER: AF Clinic|OTHER: Care as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 24-Week Treatment Study to Compare Standard of Care Versus the eMDPI DS in Participants 13 Years or Older With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone propionate/salmeterol (FS)|DRUG: Albuterol|DRUG: Standard of Care Asthma Medication|DRUG: Standard of Care Rescue Medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-term Follow-up Study to Evaluate the Impact of Lumicitabine on the Incidence of Asthma and/or Wheezing in Infants and Children With a History of Respiratory Syncytial Virus Infection
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: Lumicitabine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Rivastigmine in the Treatment of Postoperative Delirium: a Pilot Clinical Trial
Status: COMPLETED
Conditions: Delirium|Postoperative Cognitive Dysfunction
Interventions: DRUG: Rivastigmine Patch|OTHER: Placebo Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Heat Loss in Humans Covered With Full-Body Blankets Connected to Different Warming Devices
Status: RECRUITING
Conditions: Heat Transfer by Clinical Warming Devices
Interventions: DEVICE: Adult blanket plus, MA2220 blanket connected to the Mistral Air, Blower MA1200-PM system.|DEVICE: Premium adult blanket, 3320 blanket connected to the Mistral Air, Blower MA1200-PM system.|DEVICE: Blanket full body, 30000 blanket connected to the 3M, Bair Hugger, Blower 775|DEVICE: FilteredFlo® Air Blanket connected to the WarmAir® Convective Warming system.|DEVICE: Blanket Full Body blanket (CLM0101) connected to the Care Essential, Cocoon, Blower CWS5000 system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Physiologic Effects of High-flow Nasal Cannula Versus Standard Oxygen Therapy Postextubation in Critically Ill Patients
Status: COMPLETED
Conditions: Ventilator Weaning
Interventions: DEVICE: High flow nasal cannula|DEVICE: Standard oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Measuring Plasticity in SFC/dACC Following Theta-Burst-Stimulation Using TMS
Status: COMPLETED
Conditions: Cognitive Control
Interventions: DEVICE: iTBS then cTBS|DEVICE: cTBS then iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Sex Hormones and Alcohol on Sleep
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: Ethanol|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing Pharmacodynamic and Pharmacokinetic Properties of Insulin Degludec and Insulin Glargine 300 U/mL at Steady-state Conditions in Subjects With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Veteran Ear Acupuncture Pilot Project
Status: COMPLETED
Conditions: Chronic Pain Syndrome|Pain|Fibromyalgia|Low Back Pain|Neuropathic Pain|Neuropathy, Painful|Musculoskeletal Pain|Chronic Pain
Interventions: PROCEDURE: Self-administration of auricular acupuncture without prosthesis|PROCEDURE: Self-administration of auricular acupuncture with prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Pilot Study to Assess the Safety of Oral Insulin in Patients With Nonalcolholic Steatohepatitis (NASH)
Status: COMPLETED
Conditions: Non-Alcoholic Steatohepatitis (NASH)|Type2 Diabetes Mellitus
Interventions: BIOLOGICAL: Oral Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Sofadil for Injection in the Treatment of Acute Ischemic Stroke
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: sofadil【Neu2000KW】|DRUG: Sofadil|DRUG: Sofadil|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Olfactory Disorders in Patients With Cardiac Amyloidosis
Status: UNKNOWN
Conditions: Amyloidosis|Cardiac Amyloidosis|Olfactory Loss|Hyposmia|Dysosmia|Smell Disorders|Taste Disorders
Interventions: OTHER: Sniffin's stick test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Perceptual Retraining to Reduce Suicide Risk
Status: COMPLETED
Conditions: Perceptual Olfactory Bias
Interventions: BEHAVIORAL: Perceptual Retraining Treatment|BEHAVIORAL: Sham Neutral training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Antibacterial Efficacy of Three Final Irrigants
Status: COMPLETED
Conditions: Endodontic Disease|Root Canal Infection
Interventions: DRUG: QMix Root Canal Irrigant|DRUG: 17%EDTA+2%Chlorhexidine|OTHER: EDTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Low-level Laser Therapy (808nm) to Muscle Fatigue Resistance
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Low-level laser therapy (808nm)|OTHER: isokinetic exercise|DEVICE: Placebo low-level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single-center, Prospective Study on the Identification and Delineation of Brain and Lung Tumors and At-Risk Organs, and Functional Testing of Surrounding Tissues Based on Dual-Energy CT
Status: RECRUITING
Conditions: Image Quality and Contouring Accuracy of the Tumor in Radiotherapy
Interventions: OTHER: Dual energy CT after routine simulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EFFECT OF AEROBIC TRAINING VERSUS MYOFACIAL RELEASE ON CLAUDICATION AMONG PREPHERAIL ARTERAIL INSUFFIECENCY PATIENTS
Status: UNKNOWN
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Electronic Treadmill device|OTHER: myofascial release technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy for BRAF-V600E Metastatic CRCm
Status: NOT_YET_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Encorafenib|DRUG: Cetuximab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Internet-based Cognitive Behavioral Self-help Treatments for People With Psychosis
Status: COMPLETED
Conditions: Schizophrenia|Hallucinations|Persecutory Delusion
Interventions: BEHAVIORAL: Internet-based, CBT-oriented, guided self-help
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Zoledronic Acid in Preventing Collapse of the Osteonecrotic Femoral Head
Status: COMPLETED
Conditions: Avascular Necrosis of Femoral Head
Interventions: DRUG: zoledronic acid (aclasta)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-finding Study to Evaluate the Effect of a Contraceptive Vaginal Ring, Releasing Nestorone® and Estradiol, on Cycle Control, Ovulation Inhibition, and Pharmacokinetics in Normal Cycling Women
Status: COMPLETED
Conditions: Suppression of Ovulation
Interventions: DRUG: 10 µg/day E2 with NES 200® µg/day|DRUG: 20 µg/day E2 with NES 200® µg/day|DRUG: 40 µg/day E2 with NES 200® µg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Buffered vs. Unbuffered Local Anesthesia in Mandibular Molars Diagnosed With Symptomatic Irreversible Pulpitis
Status: COMPLETED
Conditions: Symptomatic Irreversible Pulpitis
Interventions: DRUG: Onset Sodium Bicarbonate Inj., 8.4%, USP Neutralizing Additive Solution|DRUG: 2% lidocaine with 1:100,000 epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase1b to Evaluate Safety of AMG706 in Combination With Paclitaxel or Docetaxel for Breast Cancer
Status: COMPLETED
Conditions: Locally Recurrent and Metastatic Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: Paclitaxel|DRUG: AMG 706
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole Brain Radiotherapy (WBRT) Versus Stereotactic Radiosurgery (SRS) for 4 Upto 10 Brain Metastases
Status: TERMINATED
Conditions: Neoplasm Metastasis
Interventions: RADIATION: Stereotactic Radiosurgery|RADIATION: Whole Brain Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wharton's Jelly Eye Drops in the Treatment of Chronic Keratitis
Status: COMPLETED
Conditions: Keratitis, Ulcerative|Corneal Ulcer
Interventions: BIOLOGICAL: SygeLIX-Coll-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dry Needling and Botulinum Toxin in the Management of Poststroke Spasticity
Status: COMPLETED
Conditions: Spasticity, Muscle
Interventions: DRUG: Botulinum Toxin Type A|COMBINATION_PRODUCT: Botulinum Toxin Type A and dry needling.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Intralesional Bacillus Calmette-Guerin (BCG) Followed by Ipilimumab in Advanced Metastatic Melanoma
Status: TERMINATED
Conditions: Metastatic Melanoma
Interventions: BIOLOGICAL: Bacillus Calmette-Guérin (BCG) vaccine|DRUG: Ipilimumab|DRUG: Isoniazid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vatalanib and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: vatalanib|DRUG: pemetrexed disodium|OTHER: pharmacological study|PROCEDURE: ultrasound imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous n-3 Fatty Acids and Ventricular Tachycardia in Patients With Implantable Cardioverter Defibrillator (ICD)-Pacemaker
Status: COMPLETED
Conditions: Ventricular Tachycardia|Sudden Cardiac Death
Interventions: DRUG: Omegaven|DRUG: Isotonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Therapy for Pediatric Hodgkin Lymphoma
Status: COMPLETED
Conditions: Hodgkin Lymphoma
Interventions: DRUG: 12 Week Stanford V Chemotherapy|DRUG: 4 cycles of VAMP chemotherapy|DRUG: 2 alternating cycles of VAMP/COP chemotherapy|DRUG: 3 alternating cycles of VAMP/COP chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integration of Illness Management and Recovery Within ACT
Status: COMPLETED
Conditions: Severe Mental Illness|Schizophrenia|Bipolar Disorder
Interventions: BEHAVIORAL: Assertive Community Treatment (ACT) + Illness Management and Recovery (IMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Woodsmoke Exposure and Cardiovascular Function
Status: COMPLETED
Conditions: Respiratory Inflammation|Systemic Inflammation
Interventions: OTHER: Bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of CPAP Treatment in Elderly: Randomized Clinical Trial
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Randomized, Open Label Non-inferiority Study of NiraParib Maintenance After 3 vs. 6 Cycles of Platinum-based Chemotherapy in completeLy debUlked Advanced HRDpositive High-grade Ovarian Cancer patientS in First Line Therapy
Status: NOT_YET_RECRUITING
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma|Clear Cell Carcinoma
Interventions: DRUG: 3 cycles chemotherapy instead of 6 cycles chemotherapy|DRUG: 6 cycles chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Post-marketing Study to Evaluate a Novel Surgical Monitoring Technique Using the EARP Nerve Cuff in TLIF Surgery.
Status: RECRUITING
Conditions: Transforaminal Lumbar Interbody Fusion Surgery
Interventions: DEVICE: Nerve Cuff and Retractor System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase IV Clinical Trial to Evaluate Efficacy and Safety of MASI BONE S (Alendronate Sodium Trihydrate) in Postmenopausal Women With Osteoporosis
Status: UNKNOWN
Conditions: Osteoporosis
Interventions: DRUG: Masibone S|DRUG: Fosamax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Strategy of Home Telehealth for Management of Congestive Heart Failure(STARTEL)
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Routine Care in a HF clinic vs Home Telehealth Care for HF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PReventing EXtubation FAILure Related to Cough
Status: TERMINATED
Conditions: Patients Intubated in ICU Before Extubation
Interventions: DEVICE: Cough Assistance and Systematic Non-Invasive Ventilation|PROCEDURE: control group using the current gold standard of care after extubation, namely the manual drainage by a physiotherapist and the consensual use of Non-invasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sacubitril/Valsartan Versus Amlodipine in Hypertension and Left Ventricular Hypertrophy.
Status: RECRUITING
Conditions: Hypertension|Left Ventricular Hypertrophy
Interventions: DRUG: sacubitril/valsartan|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Immunogenicity and Safety BBIBP-CorV Vaccine for COVID-19 in Adults in Guinea
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19|Vaccine Adverse Reaction|Sars-CoV-2 Infection|Healthy Volunteer
Interventions: BIOLOGICAL: BBIBP-CorV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Hardaliye, a Fermented Grape Drink, on Oxidative Stress, Lipid Profile and Blood Pressure in Young Footballers
Status: COMPLETED
Conditions: Diet, Healthy|Antioxidative Stress
Interventions: OTHER: Grape juice|OTHER: Placebo drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nebivolol 0.5, 1.0, or Timolol 0.5 Suspension Compared to Timolol 0.5 Solution to Treat Glaucoma/Ocular Hypertension
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Nebivolol Ophthalmic Suspension 1 Percent|DRUG: Nebivolol Ophthalmic Suspension 0.5 Percent|DRUG: Timolol Ophthalmic Suspension 0.5 Percent|DRUG: Timolol Ophthalmic Solution 0.5 Percent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of PSMA-based 18F-DCFPyL PET/CT to Conventional Imaging in the Evaluation of Patients With Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: 18F DCFPyL- Radiopharmaceutical
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optimization of the Surgical Care Pathway for Kidney Tumors by Digitizing Perioperative Nursing Coordination (UroCCR 126)
Status: RECRUITING
Conditions: Digitizing Perioperative Nursing Coordination
Interventions: OTHER: Uroconnect Follow Up Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: I MOVE!+UP: Piloting an Integrated Weight Management Program for Veterans With PTSD
Status: RECRUITING
Conditions: PTSD|Overweight and Obesity
Interventions: BEHAVIORAL: I MOVE!+UP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: EPO906 Therapy in Patients With Advanced Ovarian, Primary Fallopian, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasms|Peritoneal Neoplasms|Fallopian Tube Neoplasms
Interventions: DRUG: epothilone b
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Haploidentical-Cord Blood Transplantation for Adults and Children
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndrome|Multiple Myeloma|Lymphoma
Interventions: DRUG: Fludarabine-Melphalan & Rabbit antithymocyte globulin (r-ATG)|PROCEDURE: Stem Cell Transplant|PROCEDURE: Stem Cells Collections|DRUG: Fludarabine, Thiotepa, Antithymocyte globulin (ATG), and Total Body Irradiation (TBI)|DRUG: Fludarabine, Busulfan, and ATG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of Rhomboid Intercostal Block and Erector Spinal Plane Block on Myofascial Pain Syndrome
Status: COMPLETED
Conditions: Myofascial Pain Syndrome
Interventions: PROCEDURE: Rhomboid intercostal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acute Microbial Switch
Status: RECRUITING
Conditions: Insulin Sensitivity|Glucose Metabolism Disorders (Including Diabetes Mellitus)|Hyperinsulinism
Interventions: DIETARY_SUPPLEMENT: Two day supplementation of a complex fiber mixture|DIETARY_SUPPLEMENT: Placebo supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The UPPROACH (Upfront Intensity Modulated Proton Beam Therapy) Approach
Status: RECRUITING
Conditions: Endometrial Cancer
Interventions: DRUG: carboplatin and paclitaxel|RADIATION: pelvic IMPT (Intensity Modulated Proton Therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of 5-fluorouracil (5-FU), Nab®1-paclitaxel, Bevacizumab, Leucovorin, and Oxaliplatin in Patients With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreas Adenocarcinoma
Interventions: DRUG: 5FU|DRUG: nab-paclitaxel|DRUG: bevacizumab|DRUG: calcium leucovorin|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hair Growth Efficacy and Safety of NGF-574H in Adult With Androgenic Alopecia
Status: COMPLETED
Conditions: Androgenic Alopecia
Interventions: OTHER: conditioned media of umbilical cord blood-derived stem cells|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intensity-Modulated Radiation Therapy or 3-Dimensional Conformal Radiation Therapy in Decreasing Hearing Loss in Patients Who Have Undergone Surgery for Parotid Tumors
Status: UNKNOWN
Conditions: Head and Neck Cancer|Ototoxicity|Radiation Toxicity
Interventions: PROCEDURE: adjuvant therapy|PROCEDURE: assessment of therapy complications|PROCEDURE: quality-of-life assessment|RADIATION: 3-dimensional conformal radiation therapy|RADIATION: intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: School-based IPT-G for Adolescents With Depression in Nepal: a Pilot Realist C-RCT
Status: NOT_YET_RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: Interpersonal Psychotherapy Group|BEHAVIORAL: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of PTG-100 in the Treatment of Moderate to Severe Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: PTG-100|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prolonged Remission Induced by Phenofibrate in Children Newly Diagnosed With Type 1 Diabetes.
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Phenofibrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomised Study Comparing Discharge 3 Days After Surgery to Home Within 24 Hours After Laparoscopic Hysterectomy.
Status: UNKNOWN
Conditions: Women Who Undergo a Laparoscopic Hysterectomy for Benign Disease.
Interventions: OTHER: shorter hospitalization stay|OTHER: questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: FIT (Fast Infarction Treatment): Complete Revascularization During Primary Percutaneous Coronary Intervention (PCI) Can be Achieved Safely With an Improved Clinical Outcome During the Indexed Hospitalization.
Status: UNKNOWN
Conditions: Myocardial Infarction|Ischemia|Heart Failure|Necrosis|Stents
Interventions: PROCEDURE: Coronary angioplasty all lesions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Myeloid Leukemia (CML)|Acute Myelogenous Leukemia (AML)|Myelodysplastic Syndrome (MDS)|Juvenile Myelomonocytic Leukemia (JMML)|Acute Lymphoblastic Leukemia (ALL)|Lymphoma (Hodgkin's and Non-Hodgkin's)
Interventions: DEVICE: CliniMACS CD34+ Reagent System|DRUG: Thiotepa|DRUG: Cyclophosphamide|DRUG: Alemtuzumab|DRUG: Tacrolimus|DRUG: Melphalan|DRUG: Busulfan|DRUG: Fludarabine|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blueberry-protein Supplementation and Exercise
Status: COMPLETED
Conditions: Inflammatory Response
Interventions: DIETARY_SUPPLEMENT: Blueberry-protein gel|DIETARY_SUPPLEMENT: Blueberry gel|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of HS-10382 in Patients With Chronic Myeloid Leukemia.
Status: RECRUITING
Conditions: CML, Chronic Phase|CML, Accelerated Phase
Interventions: DRUG: HS-10382(Part 1: Dose escalation)|DRUG: HS-10382(Part 2: Dose expansion)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biportal Endoscopic Discectomy Versus Microdiscectomy: RCT, Non-inferiority Trial
Status: COMPLETED
Conditions: Lumbar Herniated Intervertebral Disc
Interventions: PROCEDURE: Biportal endoscopy|PROCEDURE: Microdiscectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Hyperproteic Hyperenergetic Enteral Formula on Body Composition and VEGF in AML During Hospital Stay
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia, Adult
Interventions: DIETARY_SUPPLEMENT: Experimental group|DIETARY_SUPPLEMENT: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oncaspar/Doxil/Decadron in Patients With Refractory Lymphoid Malignancies
Status: TERMINATED
Conditions: Non-hodgkins Lymphoma|Hodgkins Lymphoma|Multiple Myeloma
Interventions: DRUG: Oncaspar, Doxil, Decadron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Restrictive vs. Liberal Oxygen in Trauma
Status: ACTIVE_NOT_RECRUITING
Conditions: Trauma|Oxygen Toxicity|Wounds and Injuries
Interventions: DRUG: Restrictive oxygen|DRUG: Liberal oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Types of Bowel Preparation for Inpatient Colonoscopy
Status: TERMINATED
Conditions: Hospitalized Patients
Interventions: DRUG: PEG/electrolytes 2L/2L split dose|DRUG: Bisacodyl 15 mg and PEG/electrolytes 1L/1L split dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Clinical Study to Explore the Optimal Dosage/Administration of PM012 Tablet in Alzheimer's Disease
Status: RECRUITING
Conditions: Mild Alzheimer Disease
Interventions: DRUG: PM012|DRUG: PM012 Placebo|DRUG: Donepezil|DRUG: Donepezil placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cigarette Reduction Using the Quitbit Digital Lighter and Mobile Application for Smoking Cessation: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Gradual Cessation|BEHAVIORAL: Gradual Cessation w/ Quitbit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Outcome of Atrial Fibrillation Ablation After Permanent Pulmonary Vein Antrum Isolation With or Without Proven Left Atrial Posterior Wall Isolation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Pulmonary vein antrum isolation (PVAI)|PROCEDURE: PVAI plus left atrial posterior wall (LAPW) isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT for Evaluation of Online Social Networking Intervention in Smoking Cessations
Status: UNKNOWN
Conditions: Self Efficacy|Health Behavior
Interventions: BEHAVIORAL: Basic health education messages|BEHAVIORAL: WeChat interactive peer support group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using TRAP to Evaluate the Effect of Zometa on Bone Metastasis Due to Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-Small Cell Lung|Carcinoma, Small Cell Lung|Metastases
Interventions: DRUG: zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Virtual Training for Latino Caregivers to Manage Symptoms of Dementia
Status: COMPLETED
Conditions: Caregiver Burden|Alzheimer Disease|Dementia|Behavioral Symptoms
Interventions: BEHAVIORAL: STAR-Caregivers Virtual Training & Follow-up (STAR-VTF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Extended Mesenteric Excision in Ileocolic Resections for Crohn's Disease
Status: RECRUITING
Conditions: Crohn Disease|Recurrence|Crohn's Ileocolitis
Interventions: PROCEDURE: Extensive mesentery resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Standardized Home Spirometry Method in Normal Population
Status: COMPLETED
Conditions: Mobile Applications|Healthy Volunteers|Feasibility Study
Interventions: DEVICE: Investigational Mobile Medical Software Application & IT Dashboard Application, FDA approved Bluetooth spirometer, FDA approved pulse oximeter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Safety and Efficacy of Pembrolizumab (MK-3475) in Combination With TS-1+Cisplatin or TS-1+Oxaliplatin as First Line Chemotherapy in Gastric Cancer (MK-3475-659/KEYNOTE-659)
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Oxaliplatin|DRUG: TS-1|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhaled Loxapine vs Intramuscular (IM) Haloperidol + Lorazepam for Agitation
Status: TERMINATED
Conditions: Agitation,Psychomotor|Haloperidol Causing Adverse Effects in Therapeutic Use|Lorazepam Causing Adverse Effects in Therapeutic Use|Loxapine Causing Adverse Effects in Therapeutic Use
Interventions: DRUG: Haloperidol + lorazepam|DRUG: Loxapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of the Effect of Adjuvant Chemotherapy With Doxorubicin and Ifosfamide With Mesna in the Treatment of High-Grade Adult Extremity Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: doxorubicin|DRUG: ifosfamide|DRUG: mesna
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Inhaled Lavender and Bergamot Oil on Anxiety and Sleep Quality in Intensive Care Patients.
Status: COMPLETED
Conditions: Patient Undergoing Surgery
Interventions: OTHER: aromatherapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Determining Dietary Pattern Accompanying Egg Intake Using Remote Food Photography Method
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Insulin Resistance
Interventions: BEHAVIORAL: Egg breakfast|BEHAVIORAL: Egg breakfast with high saturated fat|BEHAVIORAL: Cereal breakfast|BEHAVIORAL: Cereal breakfast with high saturated fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: RESOLUTE Japan SVS: The Clinical Evaluation of the MDT-4107 DES in the Treatment of De Novo Lesions in Small Diameter Native Coronary Arteries
Status: COMPLETED
Conditions: Arterial Occlusive Diseases|Myocardial Ischemia|Cardiovascular Diseases|Coronary Artery Disease
Interventions: DEVICE: MDT-4107 Zotarolimus-Eluting Coronary Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Distribution of Biospecimens From Biorepositories/Biobanks for Research Use
Status: WITHDRAWN
Conditions: Cancer|Pregnancy Related|Gastro-Intestinal Disorder|Cardio-Respiratory Distress|Women's Health: Endometriosis|Autoimmune Diseases|Nephritis|Healthy|Neuro-Degenerative Disease
Interventions: PROCEDURE: Specimens obtained from surgical, phlebotomy or other non-invasive procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bio-significance of LPC16:0 in Fibromyalgia
Status: RECRUITING
Conditions: Fibromyalgia, Primary|Pain|Soreness, Muscle|Oxidative Stress|Metabolomics|Lipidomics
Interventions: DRUG: Pregabalin 150mg, imipramine 25mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of the Efficacy of tDCS in the Treatment of Complex Regional Pain Syndrome (CRPS) Type 1
Status: COMPLETED
Conditions: Reflex Sympathetic Dystrophy
Interventions: DEVICE: transcranial direct current stimulation (tDCS) (active or placebo)|DEVICE: Graded motor imagery (GMI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open Angle Glaucoma
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: Latanoprost-PPDS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Dosimetry for Holmium-166 Radioembolization in Patients With Unresectable Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Carcinoma, Hepatocellular
Interventions: DEVICE: 166Holmium microspheres (QuiremSpheres®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT