pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Web-based Guided Self-Determination Intervention for Adults With Type 2 Diabetes in General Practice
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Guided self-determination programme (GSD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Etelcalcetide on Cardiac Hypertrophy in Hemodialysis Patients
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism|Chronic Kidney Disease Requiring Chronic Dialysis|Left Ventricular Hypertrophy
Interventions: DIAGNOSTIC_TEST: cardiac MRI|DIAGNOSTIC_TEST: echocardiography with strain|DIAGNOSTIC_TEST: Laboratory tests|DIAGNOSTIC_TEST: Body composition monitoring|DIAGNOSTIC_TEST: lung ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognition-preserving Brain Irradiation for Treating Patients With Intracranial Meningioma in the Era of Modern Radiotherapeutic Techniques Including Proton Beam Therapy - a Prospective Study Focusing on Radiological Outcomes and Neurocognitive Endpoints
Status: NOT_YET_RECRUITING
Conditions: Intracranial Meningioma
Interventions: RADIATION: Radiation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Effect of SlimBiotics L. Fermentum K8 Postbiotic on Weight Management and Metabolic Health Outcomes
Status: NOT_YET_RECRUITING
Conditions: Metabolic Health|Weight Loss|Stress|Well-Being, Psychological|Sleep|Healthy Eating
Interventions: OTHER: Slimbiotics Postbiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study to Investigate the Effect of JNJ-42847922 on Polysomnography Measures in Patients With Major Depressive Disorder With Insomnia Who Are Stably Treated With Antidepressants
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: JNJ-42847922|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Non-resectable Bile Duct Cancer With Radiofrequency Ablation or Photodynamic Therapy
Status: RECRUITING
Conditions: Hilar Cholangiocarcinoma
Interventions: DRUG: Photosensitizer|PROCEDURE: Radiofrequency ablation (RFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of GS-4774 for the Treatment of Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic HBV Infection
Interventions: BIOLOGICAL: GS-4774|DRUG: OAV Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxycycline in Treatment of Bleeding With Depot Medroxyprogesterone Acetate (DMPA)
Status: COMPLETED
Conditions: Uterine Hemorrhage
Interventions: DRUG: Doxycycline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on Efficacy of rTMS to Improve ECT in Treatment-Resistant Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: active rTMS-ECT|DEVICE: sham rTMS-ECT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IgIV Plus Prednisone vs High-dose Dexamethasone for ITP
Status: RECRUITING
Conditions: Immune Thrombocytopenia (ITP)
Interventions: DRUG: Neofordex®|DRUG: Intravenous immunoglobulins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Lymphoid Tumor Microenvironmental Dysruption Prior to Autologous Stem Cell Transplantation
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia|Lymphoma|Multiple Myeloma
Interventions: DRUG: Plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CARES-Spine (Comprehensive Analgesic, Recovery, and Education Support for Spine Surgery) Trial
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain|Back Pain|Neck Pain|Opioid Misuse
Interventions: DRUG: Tizanidine|BEHAVIORAL: MI-Opioid Taper|DRUG: Placebo|BEHAVIORAL: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sildenafil Citrate on Uteri- Placental Perfusion, Doppler Indices in Growth Restricted Fetuses
Status: COMPLETED
Conditions: Pregnancy Complication
Interventions: DRUG: sildenafil citrate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Deucravacitinib (BMS-986165) for Pityriasis Rubra Pilaris
Status: RECRUITING
Conditions: Pityriasis Rubra Pilaris
Interventions: DRUG: Deucravacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Disease Management Study Targeted to Reduce Health Care Utilization for Patients With Congestive Heart Failure
Status: UNKNOWN
Conditions: The Focus is to Investigate Effects of a Disease Management Intervention for Patients With Congestive Heart Failure
Interventions: BEHAVIORAL: Disease-Management intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing Two Types of Diets on Psychological and Gastrointestinal Symptoms
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: Paleolithic diet|OTHER: General Healthful Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia.
Status: RECRUITING
Conditions: Skin Cancer|Mucosal Neoplasm of Oral Cavity|Soft Tissue Neoplasm
Interventions: DEVICE: Radiation: Diffusing Alpha Radiation Emitters Therapy (DaRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In-person Versus Online Debriefing in HBB
Status: COMPLETED
Conditions: Neonatal Respiratory Distress
Interventions: BEHAVIORAL: On line debriefing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sorafenib and Anastrozole in Treating Postmenopausal Women With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: sorafenib tosylate|DRUG: anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep, Pain and Inflammatory Processes in Older Adults With Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis of the Knee|Insomnia|Knee Pain
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Acupoint Electrical Stimulation on Incidence of Hypotension After Spinal Anesthesia
Status: NOT_YET_RECRUITING
Conditions: Anesthesia
Interventions: DEVICE: Transcutaneous electric stimulation pretreatment|DEVICE: Transcutaneous acupoint electrical stimulation treatment|DEVICE: Transcutaneous acupoint pseudo electric stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DBS Imaging-based vs. Threshold Assessment-based Programming
Status: RECRUITING
Conditions: Deep Brain Stimulation|Parkinson Disease|Imaging
Interventions: OTHER: Imaging-based programming|OTHER: Threshold assessment-based programming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Romiplostim in Adult Subjects With Persistent or Chronic Immune Thrombocytopenia (ITP)
Status: COMPLETED
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Romiplostim|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I First in Human Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of WGI-0301 in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: WGI-0301
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Day and Night Closed-loop in Young People With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 1|Glucose Metabolism Disorders|Endocrine System Diseases|Autoimmune Diseases
Interventions: DEVICE: FlorenceM (US) and FlorenceX (UK)|DEVICE: Insulin pump therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogencity of H7N9 Influenza Antigen With 2 Adjuvant Formulations in Healthy Adults in Brazil
Status: COMPLETED
Conditions: Influenza|H7N9 Influenza
Interventions: BIOLOGICAL: H7N9 antigen + adjuvant IB160|BIOLOGICAL: H7N9 antigen + adjuvant SE|BIOLOGICAL: H7N9 antigen without adjuvant|BIOLOGICAL: Placebo (PBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Azithromycin/Bicillin Syphilis
Status: COMPLETED
Conditions: Syphilis
Interventions: DRUG: Azithromycin|DRUG: Benzathine Penicillin|DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COR-PRIM: Problem-based Learning (PBL) After Coronary Heart Disease (CHD) - Long-term Evaluation in Primary Care of Self-care
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: BEHAVIORAL: PBL in patient education|BEHAVIORAL: Mailed patient information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CD40 Agonist, Flt3 Ligand, and Chemotherapy in HER2 Negative Breast Cancer
Status: RECRUITING
Conditions: HER2-negative Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: PLD Chemotherapy|DRUG: CDX-1140|DRUG: CDX-301
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ALXN1840 (Non-coated) Administered With And Without Omeprazole In Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ALXN1840|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of MRG002 in the Treatment of Patients With HER2-positive Unresectable Locally Advanced or Metastatic Breast Cancer
Status: RECRUITING
Conditions: Advanced Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: MRG002|DRUG: Trastuzumab Emtansine for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Integrating Family Planning - Maternal, Newborn and Child Health (MNCH) Services on Uptake of Voluntary Modern Contraceptive Methods
Status: UNKNOWN
Conditions: Reproductive Behavior, Family Planning Services
Interventions: BEHAVIORAL: Capacity Building of Health care workers and providers to deliver integrated Family Planning and Maternal, Newborn and Child Health
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety and Tolerability of Pasireotide LAR in Combination With Everolimus in Advanced Metastatic NETs
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: RAD001|DRUG: SOM230
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AQUAVAN® Injection Versus Midazolam HCl for Sedation in Elderly Patients Undergoing Elective Colonoscopy
Status: TERMINATED
Conditions: Colonoscopy|Colon Polyps
Interventions: DRUG: fospropofol disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Antiretroviral Therapy on Metabolic, Skeletal, and Cardiovascular Parameters
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Emtricitabine/tenofovir disoproxil fumarate|DRUG: Ritonavir|DRUG: Atazanavir|DRUG: Raltegravir|DRUG: Darunavir
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Darbepoetin Alfa With or Without Iron in Treating Anemia Caused By Chemotherapy in Patients With Cancer
Status: COMPLETED
Conditions: Anemia|Leukemia|Lymphoma|Lymphoproliferative Disorder|Multiple Myeloma and Plasma Cell Neoplasm|Precancerous Condition|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: darbepoetin alfa|DIETARY_SUPPLEMENT: ferrous sulfate|DRUG: sodium ferric gluconate complex in sucrose|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using Shared Decision Making to Improve Kidney Transplantation Rates
Status: ENROLLING_BY_INVITATION
Conditions: End Stage Renal Disease|Kidney Failure
Interventions: BEHAVIORAL: Provider educational materials|BEHAVIORAL: Patient letters
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TDCS for Auditory Hallucinations in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DEVICE: transcranial Direct Current Stimulation (tDCS)|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clozapine Versus Amisulpride in Treatment-resistant Schizophrenia Patients
Status: WITHDRAWN
Conditions: Schizophrenia|Treatment Resistant Disorders
Interventions: DRUG: Clozapine|DRUG: Amisulpride|DRUG: Clozapine+Amisulpride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Frozen Blastocyst Transfer Using Conventional Timing Versus Timing by Endometrial Receptivity Analysis
Status: UNKNOWN
Conditions: Implantation Failure|Infertility, Female
Interventions: OTHER: FET according to ERA|OTHER: FET according to standard protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Efficacy and Safety Study in Patients With Ulcerative Colitis in Remission Phase
Status: COMPLETED
Conditions: Ulcerative Colitis in Remission
Interventions: DRUG: Asacol®|DRUG: Mesalazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Amniotic Membrane Wound Graft In the Management of Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: OTHER: Standard of care|OTHER: Applications of EpiFix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Myofascial Trigger Points of the Levator Scapulae Muscle
Status: COMPLETED
Conditions: Myofascial Pain Syndrome
Interventions: DIAGNOSTIC_TEST: Sonoelastography, tensiomyography and mechanosensitivity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ziprasidone Augmentation of SSRIs for Patients With Major Depressive Disorder (MDD) That do Not Sufficiently Respond to Treatment With SSRIs
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Ziprasidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Safety, Efficacy of Home RF Cosmetic Instrument in the Treatment of Facial or Periorbital Wrinkles
Status: COMPLETED
Conditions: Skin Wrinkles
Interventions: DEVICE: Home radiofrequency skin treatment instrument|OTHER: Ultrasonic coupler for medical purposes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iv Amiodarone Versus Iv Procainamide to Treat Haemodynamically Well Tolerated Ventricular Tachycardia
Status: TERMINATED
Conditions: Ventricular Tachycardia|Wide QRS Tachycardia
Interventions: DRUG: iv Amiodarone|DRUG: iv Procainamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1b/2 Study of U3-1287 in Combination With Trastuzumab Plus Paclitaxel in Newly Diagnosed Metastatic Breast Cancer (MBC)
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: U3-1287|DRUG: Trastuzumab|DRUG: Paclitaxel|DRUG: U3-1287|DRUG: Trastuzumab|DRUG: Paclitaxel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab Combined With Chemoradiotherapy in Advanced Esophageal Cancer.
Status: RECRUITING
Conditions: Esophageal Neoplasms|Esophageal Diseases|Digestive System Neoplasms
Interventions: DRUG: camrelizumab|DRUG: Paclitaxel drugs|DRUG: Platinum drug|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Effect and Safety of PDT and RFA for Unresectable EHCC
Status: COMPLETED
Conditions: Cholangiocarcinoma
Interventions: PROCEDURE: Photodynamic therapy|PROCEDURE: radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic-Assisted Laparoscopic Versus Open Surgery for Complicated Hepatolithiasis
Status: UNKNOWN
Conditions: Hepatolithiasis
Interventions: PROCEDURE: Robot-assisted Laparoscopic operation|PROCEDURE: open surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Titration Efficacy and Safety of Control-released Oxycodone and Immediate-released Oxycodone in Patients With Moderate to Severe Cancer Pain
Status: COMPLETED
Conditions: Cancer|Pain
Interventions: DRUG: Oxycodone|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Prevention of Hypothermia in Pediatric Patient Between Wrapping With Cotton and Plastic.
Status: COMPLETED
Conditions: Perioperative Hypotension|Prevention|Child
Interventions: PROCEDURE: Plastic wrap (study group) and cotton (control group) wrap.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: An Investigation of the Impact of Localized Topical Anesthesia of the Ocular Surface on End-of-day Contact Lens Discomfort
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DIAGNOSTIC_TEST: Local Anesthesia|DIAGNOSTIC_TEST: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Standard Deep Anterior Lamellar Keratoplasty (S-DALK) and Intralase Enabled Deep Anterior Lamellar Keratoplaty (IE-DALK)
Status: UNKNOWN
Conditions: DALK Corneal Transplant|Keratoconus|Scar
Interventions: PROCEDURE: Standard Deep Anterior Keratoplasty (S-DALK)|PROCEDURE: IE-DALK (femtosecond)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of Music and Dance on Cognition, Frailty, and Burden in Elderly Caregivers Living in Rural Communities
Status: UNKNOWN
Conditions: Cognitive Decline|Memory Loss|Frail Elderly Syndrome|Burden, Dependency
Interventions: OTHER: Dance|OTHER: Health care guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of Diet and Behavior in Children With Autism
Status: COMPLETED
Conditions: Autism
Interventions: DIETARY_SUPPLEMENT: Gluten and dry milk|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Changes of Venous Return After Spinal and Epidural Analgesia and Anesthesia by Ultrasound Guided Vena Cava Diameter Measurement
Status: COMPLETED
Conditions: Pregnancy Related|Hypotension, Orthostatic
Interventions: DIAGNOSTIC_TEST: Inferior vena cava ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Serotonin Selective Reuptake Inhibitor (SSRI) Effects on Cerebral Connectivity in Acute Ischemic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Fluoxetine|DRUG: Placebo|RADIATION: fMRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Histological Effect of Various Microfracture Techniques on Human Chondral & Sub-chondral Tissue - an Ex-Vivo Study
Status: UNKNOWN
Conditions: Partial or Total Hip Arthroplasty|Ex-vivo Preparat of Femoral Head
Interventions: PROCEDURE: microfracture techniques
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Safety and Tolerability of MEDI-551 in Scleroderma
Status: COMPLETED
Conditions: Scleroderma
Interventions: BIOLOGICAL: MEDI-551|BIOLOGICAL: Placebo|BIOLOGICAL: MEDI-551|BIOLOGICAL: MEDI-551|BIOLOGICAL: MEDI-551|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dutch Multidomain Lifestyle Intervention in Older Adults at Risk of Cognitive Decline
Status: ACTIVE_NOT_RECRUITING
Conditions: Cognitive Decline|Life Style|Risk Reduction
Interventions: BEHAVIORAL: Multidomain lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Acupressure Therapy Applied to Nursing Students on Exam Anxiety and Vital Signs
Status: COMPLETED
Conditions: EXAM ANXIETY|VITAL SIGNS
Interventions: BEHAVIORAL: Akupressur
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prothrombin Complex Concentrate vs Fresh Frozen Plasma in Goal-directed Bleeding Management in Non-cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer|Spine, Open|Hip Osteoarthritis|Knee Disease
Interventions: BIOLOGICAL: fresh frozen plasma|BIOLOGICAL: prothrombin complex concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Peripheral Nerve Block After Minimally Invasive Colon Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain, Postoperative|Pain, Abdominal|Analgesia|Surgery|Colon Cancer|Injection Site
Interventions: DRUG: Active drug|DRUG: Placebo|PROCEDURE: Injection of Ropivacaine - Ultrasound-guided transverse abdominal plane block|PROCEDURE: Injection of Ropivacaine - Laparoscopic assisted transverse abdominal plane block|PROCEDURE: Injection of placebo - Ultrasound-guided transverse abdominal plane block|PROCEDURE: Injection of placebo - Laparoscopic assisted transverse abdominal plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Metabolic Control of Once to Twice-daily Insulin Detemir Injections
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Levemir (insulin detemir)|DRUG: Levemir twice a day
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of AVE5026 as Compared to Enoxaparin for the Prevention of Thromboembolism in Patients Undergoing Total Hip Replacement Surgery
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Semuloparin sodium|DRUG: Enoxaparin sodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Cryotherapy Combined to TENS Burst in Patients With Non-specific Chronic Lombar Pain
Status: UNKNOWN
Conditions: Chronic Low Back Pain
Interventions: OTHER: Cryotherpy|OTHER: TENS Burst|OTHER: TENS Burst Placebo|OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Nurse-Led, Symptom-Based Screening of Household Child Contacts of Tuberculosis Index Cases
Status: COMPLETED
Conditions: Tuberculosis
Interventions: OTHER: Symptom -based Screening(Child Contacts)|OTHER: Clinical based Decisions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Toripalimab Plus Stereotactic Body Radiotherapy for HCC With PVTT
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Toripalimab|RADIATION: Stereotactic body radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Pregabalin and Lidocaine to Reduce Chronic Breast Cancer Pain
Status: COMPLETED
Conditions: Post-mastectomy Pain Syndrome|Chronic Post-surgical Pain
Interventions: DRUG: Intraoperative Intravenous Lidocaine Infusion|DRUG: Perioperative Pregabalin|DRUG: Perioperative Pregabalin Placebo|DRUG: Intraoperative Intravenous Lidocaine Placebo Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Intraoperative Dexamethasone on Post-op Dry Eye
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: dexamethasone intraocular suspension, 9%|DRUG: Prednisolone Acetate 1% Oph Susp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Cue-based Developmental Approach Toward the Preterm Infants During Feeding Transition Period
Status: UNKNOWN
Conditions: Preterm Infant|Feeding Behavior|Feeding Patterns
Interventions: OTHER: The premature infant oral motor intervention (PIOMI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Tocilizumab and Methotrexate Treatment Strategies (Adding Tocilizumab to Methotrexate Versus Switching to Tocilizumab) in Patients With Active Rheumatoid Arthritis With Inadequate Response to Prior Methotrexate Treatment
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab [RoActemra/Actemra]|DRUG: methotrexate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low PSMA SUV Boost (LPS-Boost): Intensified 177Lu-PSMA-617 Treatment for Patients With Metastatic Castrate-Resistant Prostate Cancer With Low PSMA Expressing Disease
Status: NOT_YET_RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Prostate Carcinoma|Stage IVB Prostate Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|PROCEDURE: Computed Tomography|DRUG: Lutetium Lu 177 Vipivotide Tetraxetan|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: PSMA PET-CT Scan|OTHER: Questionnaire Administration|PROCEDURE: Single Photon Emission Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Passive and Active Joint Mobilization for Chronic Ankle Instability
Status: UNKNOWN
Conditions: Musculoskeletal Manipulations|Chronic Instability of Joint|Ankle Joint
Interventions: OTHER: Active joint mobilization|OTHER: Passive joint mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tarceva vs. Avastin+Tarceva for Advanced NSCLC With EGFR m(+)
Status: UNKNOWN
Conditions: EGFR Positive Non-small Cell Lung Cancer
Interventions: DRUG: Erlotinib plus Bevacizumab|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Diabetes After Transplantation by Vildagliptin in the Early Post-transplant Period
Status: RECRUITING
Conditions: Disorder Related to Renal Transplantation|Diabetes
Interventions: DRUG: Vildagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Alcohol Detoxification in Primary Care Treatment (ADEPT)
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: Acamprosate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radial Extracorporeal Shock Wave Therapy for Acute Hamstring Muscle Complex Injury Type 3b in Athletes
Status: UNKNOWN
Conditions: Athletic Injuries
Interventions: DEVICE: rESWT|DEVICE: Sham-rESWT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Sertraline in Young Children With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: Sertraline Liquid Placebo|DRUG: Sertraline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of SpiroGym App in Patients With Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Expiratory muscle strength training + SpiroGym application|DEVICE: Expiratory muscle strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of ENTREN-F Program: A Psycho-family Intervention in Childhood Obesity
Status: COMPLETED
Conditions: Childhood Obesity
Interventions: BEHAVIORAL: ENTREN|BEHAVIORAL: ENTREN-F|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Two NovoLog® Formulations in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin aspart|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy and Safety of BENEV Exosome Regenerative Complex+ for Self-perceived Thinning Hair
Status: NOT_YET_RECRUITING
Conditions: Thinning Hair
Interventions: OTHER: BENEV Exosome Regenerative Complex+
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Difluoromethylornithine (DFMO) and AMXT-1501 for Neuroblastoma, CNS Tumors, and Sarcomas
Status: NOT_YET_RECRUITING
Conditions: Atypical Teratoid/Rhabdoid Tumor|Neuroblastoma Recurrent|Embryonal Tumor With Multilayered Rosettes|DIPG Brain Tumor|Ewing Sarcoma|Osteosarcoma Recurrent
Interventions: DRUG: Difluoromethylornithine (DFMO)|DRUG: AMXT-1501 Dicaprate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Effects of Improving the Carotid Artery Intima Media Thickness and Changing Lipid Levels by Cilostazol/Ginkgo Leaf Extract and Aspirin in Diabetic Peripheral Angiopathy.
Status: RECRUITING
Conditions: Diabetic Peripheral Angiopathy
Interventions: DRUG: Renexin CR 200/160mg|DRUG: Aspirin 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic Counseling or Usual Care in Helping Women With Newly Diagnosed Ductal Carcinoma In Situ or Stage I, Stage II, or Stage IIIA Breast Cancer Make Treatment Decisions
Status: COMPLETED
Conditions: Breast Cancer|Psychosocial Effects of Cancer and Its Treatment
Interventions: BEHAVIORAL: counseling intervention|OTHER: educational intervention|PROCEDURE: psychosocial assessment and care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Chewing Versus Traditional Oral Administration of Ticagrelor in STEMI Patients
Status: COMPLETED
Conditions: Acute Coronary Syndromes|ST Elevation Myocardial Infarction
Interventions: DRUG: Chewing Ticagrelor|DRUG: Oral Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiohistological Correlation of Thrombohemorrhagic Remodeling in the Acute Phase of Ischemic Stroke Managed by Decompressive Hemicraniectomy
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: OTHER: MRI sequences and biopsies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Efficacy and Safety of Peramivir in Adults With Acute Serious or Potentially Life-threatening Influenza
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: Peramivir 200 mg|DRUG: Peramivir 400 mg|DRUG: Oseltamivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anlotinib Hydrochloride Capsules Combined With TQB2450 in the Treatment of Endometrial Cancer
Status: NOT_YET_RECRUITING
Conditions: Endometrial Cancer
Interventions: DRUG: Anlotinib hydrochloride capsule + TQB2450 injection|DRUG: Chemotherapy drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of a Transcutaneous Bilirubinometer
Status: COMPLETED
Conditions: Neonatal Jaundice|Hyperbilirubinemia
Interventions: DEVICE: Transcutaneous Bilirubinometer|OTHER: visual assessment of neonatal jaundice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison Between Amniotic Fluid Lamellar Body Count and Fetal Pulmonary Artery Doppler Indices in Predicting Fetal Lung Maturity
Status: UNKNOWN
Conditions: Preterm Labour
Interventions: DEVICE: Amniotic fluid lamellar body count|DEVICE: Fetal pulmonary artery Doppler
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy of Graminex® Flower Pollen Extracts in Healthy Women With Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: OTHER: Placebo|DIETARY_SUPPLEMENT: Water soluble pollen extract fraction|DIETARY_SUPPLEMENT: Lipid soluble pollen extract fraction + water soluble pollen extract fraction|DIETARY_SUPPLEMENT: Lipid soluble pollen extract fraction|DIETARY_SUPPLEMENT: Water soluble pollen extract fraction + cranberry powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for Long-term Follow-up of Hemophagocytic Lymphohistiocytosis (HLH) Participants Who Received Treatment With Emapalumab (NI-0501), an Anti-interferon Gamma Monoclonal Antibody
Status: COMPLETED
Conditions: Hemophagocytic Lymphohistiocytosis
Interventions: DRUG: Emapalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Efficacy and Safety of ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) in Japanese Adults With Subgenotype 1b Chronic Hepatitis C Virus (HCV) Infection
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection
Interventions: DRUG: ABT-450/r/ABT-267|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of NP-011 in Healthy Volunteers
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: NP-011 (Single Ascending Dose Phase)|DRUG: NP-011 (Multiple Ascending Dose Phase)|OTHER: NP-011 (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Versus Nalbuphine in Prevention of Emergence Agitation Following Adenotonsillectomy in Pediatrics
Status: UNKNOWN
Conditions: Emergence Delirium
Interventions: DRUG: Dexmedetomidine|DRUG: Nalbuphine|DEVICE: infusion pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Exemestane (Aromasine) + Tamoxifen - Breast Neo-Adjuvant
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Exemestane|DRUG: tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study 301: BLI4900 Versus an FDA-approved Comparator in Adult Subjects Prior to Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: Bowel Prep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Admission of the Patient to the Clinic After Surgery
Status: UNKNOWN
Conditions: Post Operative Pain|Post-Op Hemorrhage|Postoperative Hypothermia|Nurse's Role
Interventions: OTHER: Experimental Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Compare Axicabtagene Ciloleucel With Standard of Care Therapy as First-line Treatment in Participants With High-risk Large B-cell Lymphoma
Status: RECRUITING
Conditions: High-risk Large B-cell Lymphoma (LBCL)
Interventions: BIOLOGICAL: Axicabtagene Ciloleucel|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Etoposide|DRUG: Rituximab|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thyroid Hormones Treatment in Asthma Exacerbation
Status: UNKNOWN
Conditions: Asthma
Interventions: DRUG: IV thyroxin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cough Desensitization Therapy: Pilot 2
Status: COMPLETED
Conditions: Cough
Interventions: BIOLOGICAL: Supra-threshold and progressive doses of diluted capsaicin via a dosimeter-controlled nebulizer|BIOLOGICAL: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: DIVINE: Dialysis Infection and Vitamin D In New England
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DRUG: Ergocalciferol|DRUG: Ergocalciferol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Intravenous Laser Irradiation of Blood Treatment With Different Colored Lights on Controlling Recurrent Stroke Risk Factors and Neurological Function in Stroke Patients
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: Intravenous Laser Irradiation of Blood
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Intervention in a Primary Healthcare Setting to Reduce Lyme Neuroborreliosis Treatment Delay
Status: UNKNOWN
Conditions: Lyme Neuroborreliosis
Interventions: OTHER: Oral and written information on tick-bites and Lyme disease
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trans Thoracic Manipulation of Ventilation/Perfusion: the V/Q System
Status: ENROLLING_BY_INVITATION
Conditions: Acute Respiratory Distress Syndrome|COVID-19
Interventions: DEVICE: V/Q System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Sedation and Analgesia Strategies on Patients With Mechanical Ventilation
Status: NOT_YET_RECRUITING
Conditions: Respiratory Insufficiency
Interventions: DRUG: Fentanyl, propofol|DRUG: fentanyl and dexmedetomindine|DRUG: Butorphanol and propofol|DRUG: Butorphanol and dexmedetomindine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Addition of Modulators of Homocysteine to Adalimumab Therapy in the Treatment of Moderate to Severe Plaque Psoriasis
Status: TERMINATED
Conditions: Psoriasis
Interventions: DRUG: Humira Then Humira plus 3 B vitamins
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ceftobiprole in the Treatment of Resistant Staphylococcus Aureus Skin and Skin Structure Infections
Status: COMPLETED
Conditions: Skin Diseases, Infectious|Skin Diseases, Bacterial|Staphylococcal Skin Infections
Interventions: DRUG: ceftobiprole medocaril|DRUG: Vancomycin plus Ceftazidime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Unplugged, a Drug Use Prevention Program: Adaptation and Evaluation of Effectiveness Among Students in Chile
Status: UNKNOWN
Conditions: Substance Use
Interventions: BEHAVIORAL: Yo Sé Lo Que Quiero (YSLQQ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Levocarnitine to Reduce Asparaginase Hepatotoxicity in Patients With Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Hepatotoxicity
Interventions: DRUG: Levocarnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Topical Antibiotic Use In Chronic Rhinosinusitis A Double-Blinded, Randomized, Placebo Controlled Study
Status: WITHDRAWN
Conditions: Rhinosinusitis
Interventions: DRUG: gentamyacin|DRUG: gentamyacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Tislelizumab Combined With Cetuximab and Irinotecan in the Treatment of Recurrent, Refractory mCRC
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Neoplasms
Interventions: DRUG: TEC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT