pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Novel E-Health Approach in Optimizing Treatment for Seniors (OPTIMUM Study)
Status: UNKNOWN
Conditions: Breast Neoplasms|Medication Adherence
Interventions: OTHER: OPTIMUM e-health tool
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Targeted Microbiome Transplant in Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis (AD)
Interventions: BIOLOGICAL: TMT Lotion|DRUG: Placebo Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Washing Pipe With a Spray Nozzle for Topical Anesthesia During Bronchoscopy
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Disease
Interventions: DEVICE: Washing Pipe With a Spray Nozzle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of Mechanical Axis vs Kinematic Alignment in Total Knee Replacement
Status: COMPLETED
Conditions: Arthroplasties|Knee Replacement
Interventions: DEVICE: OtisMed® ShapeMatch® Technology|DEVICE: Stryker Precision Knee Navigation|PROCEDURE: Total Knee Replacement|DEVICE: Stryker Triathlon® Total Knee System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating EKB-569 in Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms|Colonic Neoplasms|Rectal Neoplasms
Interventions: DRUG: EKB-569
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Contribution of Osteopathic Treatment to Classic Medical Management in Patients With Chronic Low Back Pain
Status: RECRUITING
Conditions: Chronic Low Back Pain
Interventions: OTHER: Osteopathic treatment|OTHER: Sham osteopathic treatment|OTHER: Current practice Medication treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect on Periodontal Phenotype of Flapless Piezoincission During Orthodontic Treatment
Status: RECRUITING
Conditions: Dental Malocclusion|Maxillary Deficiency
Interventions: PROCEDURE: flapless alveolar decortication with augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: UARK 2005-01 Study of Velcade, Thalidomide, and Dexamethasone (VTD) With or Without Adriamycin® in Relapsed/Refractory Patients
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Velcade, Thalidomide, Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Percutaneous Coronary Intervention to Improve Survival in Heart Failure
Status: COMPLETED
Conditions: Ischemic Cardiomyopathy
Interventions: PROCEDURE: Percutaneous Coronary Intervention|DRUG: Drug Therapy for Heart Failure|DEVICE: Device Therapy for Heart Failure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Experiential Avoidance as the Mechanism of Mindfulness Intervention in Reducing Emotional Distress: Daily Dairy Research
Status: NOT_YET_RECRUITING
Conditions: Emotional Distress
Interventions: BEHAVIORAL: Mindfulness Intervention for Emotional Distress
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Euploid Rate of Blastocyst Between PPOS and GnRH Antagonist Protocol in Patients Undergoing PGT-A
Status: RECRUITING
Conditions: Preimplantation Genetic Testing|Progestin-primed Ovarian Stimulation|Euploid Rate|GnRH Antagonist
Interventions: DRUG: GnRH antagonist|DRUG: oral Duphaston
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Feasibility Study of the Orion Visual Cortical Prosthesis System
Status: ACTIVE_NOT_RECRUITING
Conditions: Blindness, Acquired
Interventions: DEVICE: Orion Visual Cortical Prosthesis System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Comparing the Difference in Pain Control in the Pediatric General Surgery Population: to Alternate or Combine Acetaminophen and Ibuprofen?
Status: NOT_YET_RECRUITING
Conditions: Pediatric Disorder
Interventions: DRUG: Acetaminophen|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an Exercise Rehabilitation Programme With a Nasal Inspiratory Restriction Device in COPD Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Breathing Exercises|Exercise Tolerance
Interventions: DEVICE: Exercise training program with and without FB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plant Pigments for Human Health: Impact of Lycopene and Anthocyanins on Bioefficacy of Provitamin A Carotenoids From Carrots
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Purple-Red Carrot Juice|OTHER: Red Carrot Juice|OTHER: Purple Carrot Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Procalcitonin on the Management of Children Aged 1 to 36 Month Presenting With a Fever Without a Source
Status: COMPLETED
Conditions: Procalcitonin|Fever Without Source|Bacterial Infection|Bacteremia
Interventions: OTHER: Procalcitonin dosage PCT-Q test (Brahms, Germany)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Enoximone Plus Extended-Release Metoprolol Succinate in Subjects With Advanced Chronic Heart Failure
Status: TERMINATED
Conditions: Heart Failure, Congestive
Interventions: DRUG: Enoximone|DRUG: Metoprolol succinate|DRUG: Placebo to match enoximone|DRUG: Placebo to match metoprolol succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Hypoxia-induced Autophagy in the Pathogenesis of MAP
Status: NOT_YET_RECRUITING
Conditions: Hypoxia|Autophagy|Placenta|Morbidly Adherent Placenta
Interventions: DIAGNOSTIC_TEST: HIF 1α and LC3B expression and MMP-9 level
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Esthetic Outcomes of M-shaped Flap Implant Uncovering Technique Versus I-shaped Incision Around Single Implants in the Anterior Maxilla Using Pink Esthetic Score
Status: UNKNOWN
Conditions: Dental Implant Failed
Interventions: PROCEDURE: I-incision, M-flap and conventional implant exposure techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Role of Propolis Endodontic Irrigant on Post-Operative Pain
Status: COMPLETED
Conditions: Post-operative Pain|Symptomatic Irreversible Pulpitis
Interventions: DRUG: Sodium hypochlorite 5.25%|DRUG: Propolis 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reducing Non-Alcoholic Steatohepatitis
Status: ENROLLING_BY_INVITATION
Conditions: Non-alcoholic Steatohepatitis|Liver Diseases|Diabetes Mellitus, Type 2|Fibrosis, Liver
Interventions: DRUG: Empagliflozin 10 miligrams (mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomized Study Comparing the Target Volume for Limited-stage Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Carcinoma of Lung|Small Cell|Limited Stage
Interventions: RADIATION: hyperfractionated radiation therapy for both arms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab Followed by Chemoradiation and Consolidation Durvalumab for Stage III Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer|Non-small Cell Carcinoma
Interventions: DRUG: Induction Durvalumab|DRUG: Chemotherapy|RADIATION: Radiation|DRUG: Consolidation durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alternate Day Prednisone or Daily Fish Oil Supplements in Patients With Immunoglobulin A Nephropathy
Status: COMPLETED
Conditions: IGA Glomerulonephritis
Interventions: DRUG: omega-3 fatty acids|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Lanreotide Autogel 120 mg in Patients With Non-functioning Entero- Pancreatic Endocrine Tumour
Status: COMPLETED
Conditions: Non Functioning Entero-pancreatic Endocrine Tumour
Interventions: DRUG: lanreotide (Autogel formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hematopoietic Stem Cell Therapy in Chronic Wounds Using a Pressure Sore Model
Status: UNKNOWN
Conditions: Chronic Wounds|Pressure Sores|Hematopoietic Stem Cells|Wound Healing
Interventions: BIOLOGICAL: Stem cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nutritional Prevention of Exertional Muscle Dysfunction
Status: COMPLETED
Conditions: Muscle Dysfunction|Exertional Rhabdomyolysis|Muscle Strength
Interventions: DIETARY_SUPPLEMENT: Choline|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Behavioral Activation Treatment for Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia, Latent|Negative Symptoms in Schizophrenia|Behavioral Activation|Remote Medical Service
Interventions: BEHAVIORAL: behavioral activation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Managing Dysexecutive Syndrome (DS): CIHR 2011-2014
Status: COMPLETED
Conditions: Traumatic Brain Injury|Cerebrovascular Accident (CVA)|Acquired Brain Injury
Interventions: BEHAVIORAL: Conventional rehabilitation.|BEHAVIORAL: Novel rehabilitation approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarker Validation in Motor System Physiology in Attention Deficit Hyperactivity Disorder
Status: RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder Combined
Interventions: DRUG: Methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Different Methods for Healing a Palatal Donor Site
Status: COMPLETED
Conditions: Wound Heal|Graft Pain|Palate; Wound
Interventions: PROCEDURE: PRF|PROCEDURE: Essix retainer|PROCEDURE: Ozone therapy|PROCEDURE: LLLT|PROCEDURE: Collagen fleece
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Electroacupuncture and Thread Embedded Acupuncture With Dietary Intervention in Obese Patients
Status: COMPLETED
Conditions: Obesity
Interventions: PROCEDURE: Electroacupuncture|PROCEDURE: Thread embedded acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation Of PF-03715455 In Moderate To Severe Uncontrolled Asthma
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: Placebo|DRUG: PF-03715455
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: What Are the Effects of Varenicline Compared With Nicotine Replacement Therapy on Long Term Smoking Cessation and Clinically Important Outcomes?
Status: UNKNOWN
Conditions: Smoking Cessation|Cardiovascular Disease|Respiratory Disease|Myocardial Infarction|Depression|Anxiety
Interventions: DRUG: Varenicline|DRUG: Nicotine replacement therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Immunogenicity of mRNA-1653, a Combined Human Metapneumovirus (hMPV) and Parainfluenza Virus Type 3 (PIV3) Vaccine, in Healthy Adults, and Children 12 to 59 Months of Age With Serologic Evidence of Prior Exposure
Status: COMPLETED
Conditions: Human Metapneumovirus and Human Parainfluenza Infection
Interventions: BIOLOGICAL: mRNA-1653|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Tumor-Associated Antigen-Specific Cytotoxic T-Lymphocytes for Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: TAA-specific CTLs|BIOLOGICAL: TAA-specific CTLs- fixed dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-blind RCT to Investigate the Effect of Alendronate on Knee Function Following ACLR
Status: RECRUITING
Conditions: ACL Reconstruction
Interventions: DRUG: Alendronate (ALN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Physical Activity Intervention to Promote Cognitive Health, Cardiovascular Health and Sleep in Older Latinos
Status: ACTIVE_NOT_RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Tiempo Juntos Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Prophylactic Antibiotic Administration During Breast Cancer Surgery in Overweight Patients.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Ampicillin/Sulbactam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Coconut Oil for Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: Coconut Oil Beverage|OTHER: Placebo Beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Ketone Drink on Liver Glucose Production in People With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Ketosis
Interventions: DIETARY_SUPPLEMENT: Ketone - beta-hydroxybutyrate (β-OHB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Brain-Gut Function Reconstruction After Intersphincteric Resection for Ultra-Low Rectal Tumors
Status: RECRUITING
Conditions: Rectal Neoplasms
Interventions: DEVICE: Transcranial magnetic stimulation|DEVICE: Sham Transcranial magnetic stimulationt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of a Mock-up Fact-checking Extension on HPV Vaccine Misinformation: A Survey Experiment
Status: NOT_YET_RECRUITING
Conditions: HPV Vaccine
Interventions: OTHER: Mobile Weibo post screenshot with mock-up Chinese fact-checking extension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Angiography-Derived Quantitative Functional Assessment Versus Pressure-Derived FFR and IMR: The FAIR Study
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Heart Diseases|Cardiovascular Diseases|Arteriosclerosis|Coronary Stenosis|Vascular Diseases|Ischemia
Interventions: OTHER: AngioQFA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Endoscopic Bariatric Therapies (EBTs): A Retrospective and Prospective Multicenter Registry
Status: RECRUITING
Conditions: Obesity|Weight Loss|Gastro Esophageal Reflux|Bariatric Surgery Candidate
Interventions: OTHER: Endoscopic Bariatric Therapies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multiple Ascending Doses Study of CM326 Injection in Healthy Subjects
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: CM326|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Elucidating Mechanisms That Underlie the Symptomatology of Functional Dyspepsia Using Novel Techniques and Its Therapeutic Validation Using Neuromodulators
Status: RECRUITING
Conditions: Functional Disorder of Stomach|Healthy
Interventions: DRUG: Mirtazapine 15 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intrathecal Morphine for Inguinal Hernia Repair.
Status: COMPLETED
Conditions: Inguinal Hernia|Nausea|Vomiting|Pruritus|Postoperative Pain
Interventions: DRUG: intrathecal morphine 0.1 mg combined with intrathecal heavy bupivacaine 7.5 mg|DRUG: intrathecal morphine 0.4 mg combined with intrathecal heavy bupivacaine 7.5 mg|DEVICE: standard monitoring with Datex Ohmeda anesthesia monitor, GE, Finland|DRUG: intravenous cannulation and premedication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of a Web-based Decision Aid for Young Women With Breast Cancer, During the Proposal for Preservation of Fertility
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Online support decision tool|BEHAVIORAL: standard oral information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Protective Immunity Against RSV and Influenza in Experimental Human Challenge of Volunteers
Status: TERMINATED
Conditions: Respiratory Syncytial Virus Infections|Influenza, Human
Interventions: BIOLOGICAL: RSV A Memphis 37|BIOLOGICAL: Influenza A/California/04/2009
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of L Arginine to Prevent Preeclampsia
Status: COMPLETED
Conditions: Preeclampsia
Interventions: DIETARY_SUPPLEMENT: L arginine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Endovascular Treatment for Chronic Cerebrospinal Venous Insufficiency (CCSVI)
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: PROCEDURE: balloon angioplasty and/or stenting|PROCEDURE: balloon angioplasty and/or stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized, Double-Blind, Parallel, Non-Inferiority, Multicenter Trial Evaluate the Efficacy and Safety of UNCNT Compared to MELSMON in Female With Menopausal Syndrome
Status: COMPLETED
Conditions: Menopausal Syndrome
Interventions: DRUG: MELSMON|DRUG: UNCNT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: INCremental Dialysis to Improve Health Outcomes in People Starting Haemodialysis (INCH-HD)
Status: RECRUITING
Conditions: Kidney Failure
Interventions: OTHER: Incremental HD|OTHER: Conventional HD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Mediterranean Diet and High Protein Diet in Women With Polycystic Ovary Syndrome (PCOS)
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: OTHER: mediterranean diet restricted calorie|OTHER: high protein diet|OTHER: mediterranean diet restricted calorie
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of GK530G Versus CD0271 0.1% Gel and CD1579 2.5% Gel in the Treatment of Acne Vulgaris.
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: GK530G|DRUG: CD0271|DRUG: CD1579
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Therapeutic Effect Treated With Tamsulosin and Progesterone After ESWL( Extra Corporeal Shock Wave Lithotripsy) in Urinary Calculus
Status: UNKNOWN
Conditions: Urinary Calculus
Interventions: DRUG: progesterone,tamsulosin,propantheline Bromide and nifedipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Prediction and Prevention of Disease by Using Big Data in Motion Analysis
Status: UNKNOWN
Conditions: Ankylosing Spondylitis|Adolescent Idiopathic Scoliosis|Gait Analysis
Interventions: DEVICE: Inertial measurement unit sensor-based gait analysis system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PEELED INTERNAL LIMITING MEMBRANE REPOSITION
Status: RECRUITING
Conditions: Macular Holes
Interventions: PROCEDURE: Peeled ILM Reposition|PROCEDURE: ILM Peeling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Randomized Study of Telcyta + Doxorubicin Versus Doxorubicin in Platinum Refractory or Resistant Ovarian Cancer
Status: TERMINATED
Conditions: Ovarian Neoplasms
Interventions: DRUG: Telcyta|DRUG: Liposomal Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study of Venetoclax for Subjects Who Have Completed a Prior Venetoclax Clinical Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Acute Myeloid Leukemia|Multiple Myeloma|Non-Hodgkin's Lymphoma|Acute Lymphoblastic Leukemia|Cancer
Interventions: DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Recombinant Factor XIII for Prevention of Bleeding in Patients With FXIII Inherited Deficiency
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Congenital FXIII Deficiency
Interventions: DRUG: catridecacog
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Oculomotor and Cognitive Rehabilitation Using Visual Feedback in Stroke Patients
Status: RECRUITING
Conditions: Stroke|Oculomotor; Disorder|Attention Disturbances
Interventions: BEHAVIORAL: Training on eye tracker based device|BEHAVIORAL: Training with a neuropsychologist|BEHAVIORAL: Training on eye tracker based device and with a neuropsychologist
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of the Antioxidant Probucol Combined With Valsartan in Patients With IgA Nephropathy
Status: COMPLETED
Conditions: Glomerulonephritis|IGA Nephropathy
Interventions: DRUG: Valsartan|DRUG: Probucol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Port Versus Four Ports Laparoscopic Cholecystectomy and Early Postoperative Pain
Status: UNKNOWN
Conditions: Pain, Postoperative|Postoperative Nausea and Vomiting|Postoperative Complications
Interventions: PROCEDURE: Conventional laparoscopic procedure|PROCEDURE: Experimental laparoscopic procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Immunogenicity of Combined Hepatitis A/B Vaccine With MenACWY-CRM Conjugate Vaccine
Status: COMPLETED
Conditions: Meningococcal Disease|Meningococcal Meningitis|Hepatitis A|Hepatitis B
Interventions: BIOLOGICAL: MenACWY-CRM|BIOLOGICAL: Combined inactivated hepatitis A & recombinant hepatitis B|BIOLOGICAL: Recombinant hepatitis B vaccine|BIOLOGICAL: Inactivated hepatitis A vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of an Alumina Free Device Surface on BMD in Patients Implanted With an SL-PLUS™ Femoral Stem for THA
Status: COMPLETED
Conditions: Hip Osteoarthritis
Interventions: DEVICE: SL-PLUS-Stem for total hip arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Three Fraction Accelerated Partial Breast Irradiation as the Sole Method of Radiation Therapy for Low-risk Stage 0 and I Breast Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Carcinoma|Breast Cancer
Interventions: RADIATION: Three Fraction Accelerated Partial Breast Irradiation|PROCEDURE: Partial mastectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery With or Without Postoperative Intensity Modulated Radiation Therapy in Treating Patients With Urothelial Bladder Cancer
Status: TERMINATED
Conditions: Stage III Bladder Cancer|Stage IV Bladder Cancer
Interventions: RADIATION: Intensity-Modulated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: How Type I Diabetes Responds to Different Diets (Normoglucidic or Ketogenic) During Physical Activity at Altitude
Status: COMPLETED
Conditions: Diet Habit|Type I Diabetes|Activity, Motor|Control
Interventions: OTHER: physical activity outings in the mountains at a level already practised by the subjects, while maintaining their usual diet (normoglucidic or ketogenic)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Antiviral & Antifibrotic Liver Therapy in HCV + Drinkers and Non-Drinkers
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Polyenylphosphatidylcholine (PPC)|DRUG: Pegylated Interferon|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance-Guided High Intensity Focused Ultrasound for Palliation of Painful Skeletal Metastases
Status: COMPLETED
Conditions: Bone Metastasis
Interventions: DEVICE: Philips MR-guided HIFU system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Manual Diaphragmatic Activation on Diaphragm Function in Patients With Gastroesophageal Reflux Disease
Status: RECRUITING
Conditions: Diaphragm Dysfunction
Interventions: OTHER: Manual diaphragmatic activation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Effects of GLPG3667 Administered as Oral Treatment in Adult Participants With Active Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: GLPG3667|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utility of Breath-holding Test in Systemic Sclerosis
Status: COMPLETED
Conditions: Systemic Sclerosis
Interventions: OTHER: scleroderma health assessment questionnaire (SHAQ), BHT, and 6MWT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pain Control in Elderly Hip Fracture Patients: Is Intravenous Acetaminophen Superior to Oral Administration?
Status: TERMINATED
Conditions: Hip Fracture
Interventions: DRUG: IV Acetaminophen|DRUG: PO Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estramustine and Paclitaxel in Treating Patients With Prostate Cancer That Has Not Responded to Hormone Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: estramustine phosphate sodium|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of Chenodeoxycholic Acid (CDCA) in Newly Diagnosed Participants With Cerebrotendinous Xanthomatosis (CTX)
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebrotendinous Xanthomatoses
Interventions: DRUG: Chenodeoxycholic acid|DRUG: Chenodeoxycholic acid Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment the Efficacy of Vitamin D Mouth Rinse Versus Placebo in the Treatment of MIH
Status: RECRUITING
Conditions: Molar Incisor Hypomineralization
Interventions: DRUG: Vitamin D3 mouth wash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hook Plate vs Tightrope in Fixation of Fracture Distal Third Clavicle
Status: UNKNOWN
Conditions: Fracture Clavicle
Interventions: PROCEDURE: Open Reduction Internal Fixation (ORIF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparative Analysis of the Effectiveness of the Use of Nimesulide and CBD Oil in Patients With Pain in the Preauricular Region Due to the Pain-dysfunctional Syndrome of the Temporomandibular Joint.
Status: UNKNOWN
Conditions: Temporomandibular Joint Disorders|Temporomandibular Joint Dysfunction Syndrome|Temporomandibular Joint Pain
Interventions: DRUG: Cannabidiol Oil|DRUG: Nimesulide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Perineural Dexamethasone During Supraclavicular Block for Hand Surgery
Status: TERMINATED
Conditions: Surgery, Hand
Interventions: DRUG: Ropivacaine|DRUG: Dexamethasone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Desensitization Protocols in HLA-incompatible Kidney-transplant Candidates
Status: TERMINATED
Conditions: End-stage Renal Disease|Kidney Transplantation|Hla-incompatible Kidney Transplant Candidates
Interventions: DRUG: visits of tocilizumab injection (every 4 weeks, up to 5 visits)|DRUG: Rituximab 375 mg/m2 at Day-30|DRUG: Rituximab 375 mg/m2 at Day-15 (only for donors living)|OTHER: Transplant Day-0
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Esmolol in Sepsis Management:Evaluating Immunomodulatory Effects and Impact on Patient Outcomes
Status: COMPLETED
Conditions: Sepsis|Lymphocyte Disorder T|Immunologic Paralysis|Catecholamine; Overproduction|Beta-Blocker|Cytokine Storm|Sympathetic Nervous System Diseases
Interventions: DRUG: esmolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Radiolabeled Mass Balance Study Of [14C]PF-00299804 In Healthy Male Volunteers
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: [14C]PF00299804
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 1 Trial to Assess Safety, Tolerability and Pharmacokinetics of ALIA-1758 in Healthy Participants
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: ALIA-1758|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-Dose Topotecan and Peripheral Stem Cell Transplantation in Treating Patients With Refractory Cancer
Status: TERMINATED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: filgrastim|DRUG: topotecan hydrochloride|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Huaiqihuang Granule in Children With Chronic Primary Immune Thrombocytopenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Placebo|DRUG: Huaiqihuang Granule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High Dose Vitamin D for Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: Vitamin D|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Recovery of Upper Limb Paresis at Discharge After Stroke and Its Level of Use in Activities of Daily Living 3 to 6 Months Later (Post AVC-AVQ)
Status: UNKNOWN
Conditions: Stroke Rehabilitation
Interventions: DIAGNOSTIC_TEST: Scale Action Research Arm Test (ARAT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ankle Kinesio Taping on Balance and Functional Performance in Obese Females.
Status: RECRUITING
Conditions: Obesity
Interventions: OTHER: Kinesiotaping|OTHER: Placebo kinesiotaping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ketogenic and Carbohydrate Diet in Crossfit
Status: ACTIVE_NOT_RECRUITING
Conditions: Nutrition|Ketogenic Dieting|Low Glycemic Index Diet|Sport|Crossfit
Interventions: OTHER: Dietary Intervention - Ketogenic Diet (KD)|OTHER: Dietary Intervention - Low-Glycemic Index Diet (CHO-LGI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Gonadotoxic Therapies on Fertility
Status: RECRUITING
Conditions: Cancer|Fertility Issues|Fertility Preservation|Toxicity Due to Chemotherapy|Toxicity Due to Radiotherapy|Effects of Immunotherapy
Interventions: DIAGNOSTIC_TEST: Blood samples for analysis|DIAGNOSTIC_TEST: Sperm samples for analysis|OTHER: Satisfaction evaluation|OTHER: Quality of Life questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Small Intestine Submucosa (SIS) Mesh for Anterior Repair: A Pilot Study
Status: COMPLETED
Conditions: Anterior Pelvic Organ Prolapse
Interventions: DEVICE: SIS mesh (Cook Medical)|PROCEDURE: Anterior prolapse repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tubeless VATS for Peripheral Lung Nodule
Status: UNKNOWN
Conditions: Solitary Pulmonary Nodule
Interventions: DEVICE: chest tube|PROCEDURE: VATS without chest tube placement|PROCEDURE: VATS with chest tube placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food Supplementation With VSL#3 as a Support to Standard Pharmaceutical Therapy in Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: VSL#3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial to Assess the Safety and Tolerability of Influenza Virus Vaccine,(CAIV-T) in Healthy Infants
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: CAIV-T
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Evaluation of the Safety of the TriVascular Stent-Graft System in the Treatment of Abdominal Aortic Aneurysms
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm
Interventions: DEVICE: TriVascular Stent-Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Blood Flow Restriction Training on Patient With Anterior Cruciate Ligament Reconstruction
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Injuries|Atrophy|Muscle Weakness
Interventions: OTHER: Plyometric exercise with blood flow restriction|OTHER: Plyometric exercise|OTHER: Routine physiotherapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PEGASUS CRT Study: Atrial Support Study in Cardiac Resynchronization Therapy
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Atrial support pacing through cardiac resynchronization therapy. Device: RENEWAL family of CRT-D devices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3372993 in Healthy Participants and Participants With Alzheimer's Disease (AD)
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: LY3372993|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of Clonidine Lauriad® to Treat Oral Mucositis
Status: COMPLETED
Conditions: Oral Mucositis
Interventions: DRUG: Clonidine Lauriad® 50µg|DRUG: Clonidine Lauriad® 100µg|DRUG: Placebo Lauriad®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Wet Macular Degeneration Study to Compare Ranibizumab or Bevacizumab to Aflibercept
Status: COMPLETED
Conditions: Exudative Macular Degeneration
Interventions: DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reflexology's Effect on Polycystic Ovary Syndrome: A Pilot Study
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: OTHER: Reflexology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transperineal, MRI-guided, Prostate Biopsy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Transperineal, MRI-guided, prostate biopsy|PROCEDURE: Transrectal prostate biopsy (TRB):
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Accelerated TMS in Psychosis
Status: ENROLLING_BY_INVITATION
Conditions: Schizophrenia|Schizoaffective Disorder|Prodromal Schizophrenia
Interventions: DEVICE: repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Satisfaction Following Cesarean Section
Status: COMPLETED
Conditions: Pain, Postoperative|Cesarean Section Complications|Postpartum Disorder|Opioid Use
Interventions: OTHER: Oxycodone Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Efficiency of Periarticular Multimodal Drug Injection in Pain Management Following Primary Unilateral TKA
Status: RECRUITING
Conditions: Arthritis Knee|Pain|Arthroplasty Complications
Interventions: PROCEDURE: primary unilateral TKA|DRUG: Bupivacain|DRUG: ketorolac|DRUG: epinephrine|DRUG: Paracetamol|DRUG: Ketorolac|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Osteopathic Intervention on Cervical Muscles in Tension Headaches in Women
Status: NOT_YET_RECRUITING
Conditions: Tension Headaches
Interventions: OTHER: Placebo Technique|OTHER: Stretching technique|OTHER: Inhibition of the suboccipital
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of Ublituximab in Participants With Relapsing Forms of Multiple Sclerosis (RMS)
Status: COMPLETED
Conditions: Relapsing Multiple Sclerosis (RMS)
Interventions: BIOLOGICAL: Ublituximab|DRUG: Teriflunomide|DRUG: Oral Placebo|DRUG: IV Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: iTEST: Introspective Accuracy as a Novel Target for Functioning in Psychotic Disorders
Status: RECRUITING
Conditions: Schizophrenia|Schizo Affective Disorder|Psychotic Disorders
Interventions: BEHAVIORAL: iTEST
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determining the Maximum Tolerated Dose of Low Dose Interferon-alpha in Conjunction With Nilotinib in Pretreated Philadelphia Chromosome Positive (Ph+) Chronic Myeloid Leukemia Patients in Chronic Phase (CML-CP)
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Nilotinib, interferon-alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Estradiol Valerate Versus Oral Contraceptive Pill in Invitro Fertilization Patients
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Levonorgestrel and ethinylestradiol|DRUG: Estradiol valerate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pressure Support During Chest Wall Compression
Status: COMPLETED
Conditions: Respiration, Artificial|Critical Care
Interventions: DEVICE: Chest wall compression plus increase of 10 cmH2O in inspiratory pressure during Pressure Support Ventilation for ten minutes in chest.|DEVICE: Chest wall compression for ten minutes in chest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Evaluating Lung Doppler Signals in Patients With Systemic Sclerosis (SSc)
Status: TERMINATED
Conditions: Systemic Sclerosis|Pulmonary Hypertension
Interventions: RADIATION: Doppler ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Physiological Study of Minimally Invasive ECCO2R in Exacerbations of COPD Requiring Invasive Mechanical Ventilation
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: extracorporeal CO2 removal (Hemolung device)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Morphological Concordance Between CT and Cone Beam in Sinus Imagery
Status: COMPLETED
Conditions: Sinonasal Pathologies
Interventions: RADIATION: Computed Tomography|RADIATION: Cone Beam Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Anti-HIV Effects of Saquinavir Soft Gelatin Capsules Versus Indinavir in Patients Who Have Used Saquinavir Hard Gelatin Capsules for One Year
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Saquinavir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT