pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Trial of a Next Generation COVID-19 Vaccine Delivered by Inhaled Aerosol
Status: NOT_YET_RECRUITING
Conditions: COVID-19 Infection
Interventions: BIOLOGICAL: ChAd-triCoV/Mac|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of CBS-2004 in Prevention of Travelers' Diarrhea
Status: WITHDRAWN
Conditions: Traveler's Diarrhea
Interventions: DRUG: CBS 2004 (galacto-oligosaccharides)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Healthy And Positive Pathways for Young People With Type 1 Diabetes (HAPPY T1D)
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: Psychoeducation to reduce diabetes distress and improve glycemic outcomes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OPtimizing Aldosterone Receptor Antagonist Therapy by Sodium Zirconium Cyclosilicate in Heart Failure
Status: RECRUITING
Conditions: Heart Failure|Hyperkalemia
Interventions: DRUG: Sodium zirconium cyclosilicate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraocular Anti-VEGF Compared With Intraocular Triamcinolone in Patients With Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Bevacizumab (Avastin)|DRUG: Triamcinolone|DRUG: Sham|PROCEDURE: Lucentis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation Assessment and Progress Tracking System Based on Video Images for Dysphagic Patients
Status: ENROLLING_BY_INVITATION
Conditions: Healthy|Head and Neck Cancer
Interventions: DEVICE: Rehabilitation assessment software|DEVICE: VFSS and FOIS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Research of Qi Deficiency and Blood Stasis Syndrome (Different Disease With Syndrome)
Status: UNKNOWN
Conditions: Ischemic Heart Failure
Interventions: DRUG: Yiqi prescription|DRUG: Huoxue prescription|DRUG: Buyang huanwu decoction|DRUG: QISHEN YIQI DRIPPING PILLS|DRUG: Placebo 1|DRUG: Placebo 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of HLX3 vs Adalimumab in Chinese Healthy Subjects
Status: COMPLETED
Conditions: Immune System Disorder
Interventions: DRUG: HLX03|DRUG: adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Two Types of Transalveolar Sinus Floor Elevation
Status: UNKNOWN
Conditions: Dental Implant|Sinus Floor Augmentation
Interventions: DEVICE: traditional TSFE|PROCEDURE: bone grafting materials|DEVICE: TSFE by DASK drills|PROCEDURE: without bone grafting materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep Well Despite Persistent Pain Symptoms
Status: NOT_YET_RECRUITING
Conditions: Insomnia Chronic|Insomnia Due to Medical Condition|Pain, Chronic
Interventions: BEHAVIORAL: Sleep-Well despite persistent pain|BEHAVIORAL: TAU (treatment-as-usual)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Mesenchymal Human Stem Cell Infusion Therapy for Endothelial DySfunctiOn in Diabetic Subjects With Symptomatic Ischemic Heart Disease. (ACESO-IHD)
Status: RECRUITING
Conditions: Diabetes Mellitus|Ischemic Heart Disease
Interventions: DRUG: 100 million Allogeneic Mesenchymal Human Stem Cells|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Observational Study of Family-based Interventions for Children With Neuropsychiatric and/or Psychiatric Disorders
Status: COMPLETED
Conditions: ADHD|Asperger Syndrome|Child Behavior Disorders
Interventions: OTHER: LAKU family program|OTHER: Etä-LAKU family program|OTHER: Family therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Norepinephrine and Phenylephrine for Maternal Cardiac Output During Spinal Anesthesia for Elective Cesarean Delivery
Status: UNKNOWN
Conditions: Hypotension
Interventions: DRUG: Norepinephrine|DRUG: Phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oral β- Glucan Supplement on Appetite and Insulin Resistance in Non Alcoholic Fatty Liver Disease
Status: UNKNOWN
Conditions: Non Alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: β- glucan|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Tolerability Study of Apremilast to Treat Early Oligoarticular Psoriatic Arthritis.
Status: COMPLETED
Conditions: Arthritis, Psoriatic
Interventions: DRUG: Apremilast (CC-10004)|OTHER: Apremilast (CC-10004) Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Head-to-head Comparison of MRI, CT, 18F-FDGal and 18F-choline in Patients With Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DIAGNOSTIC_TEST: 18F-FDGal PET/CT versus 18F-choline PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Trial to Investigate the Pharmacokinetics and the Effect on ECG of Escitalopram in Elderly Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Online Education Given to Parent on Motor Social Development for The Premature Babies in The Neonatal Intensive Care Unites
Status: COMPLETED
Conditions: Premature Infant
Interventions: OTHER: online education program|OTHER: no online education program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sequential Infusion of CD19 and BCMA CAR-T Cells to Improve PTR in Patients With AL
Status: UNKNOWN
Conditions: Platelet Transfusion Refractoriness|Acute Leukemia in Remission
Interventions: BIOLOGICAL: CAR-T infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Electrophysiological Markers Related to the Cognitive and Affective Processes Behind Empathic Behaviour in Schizophrenic Spectrum Disorder
Status: RECRUITING
Conditions: Schizophrenia
Interventions: OTHER: Evoked Related Potentials
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: DepoCyt for Active Lymphomatous or Leukemic Meningitis
Status: TERMINATED
Conditions: Neoplastic Meningitis|Lymphoma, B Cell
Interventions: DRUG: cytarabine liposome injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Technological Innovations in Behavioral Treatments for Cigarette Smoking
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: BEHAVIORAL: Reinforcement for the abstinence of smoking|BEHAVIORAL: Reinforcement for submission of videos with CO sample
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Tri Association in Patient With Advanced Epithelial Ovarian Cancer in Relapse
Status: UNKNOWN
Conditions: Epithelial Ovarian Cancer|Relapse
Interventions: DRUG: Bevacizumab, Olaparib and Durvalumab (MEDI 4736) combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Joint Arthroplasty and Sleep
Status: COMPLETED
Conditions: Primary Total Hip Arthroplasty|Primary Total Knee Arthroplasty
Interventions: DRUG: Diphenhydramine (Benadryl)|DIETARY_SUPPLEMENT: Melatonin|BEHAVIORAL: Sleep Hygiene Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MEMP1972A in the Prevention of Allergen-Induced Airway Obstruction in Patients With Mild Asthma (SOLARIO)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: MEMP1972A|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Efficacy and Safety of Fluticasone Furoate Nasal Sprays (FFNS) 55 Microgram (mcg) and 110 mcg in Chinese Pediatric Subjects With Allergic Rhinitis (AR)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial and Seasonal|Rhinitis, Allergic
Interventions: DRUG: FFNS|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Isolated Pelvic Perfusion With TNF-α 0.3 mg and Melphalan 1.5 mg/kg Versus Standard Treatment in Patients With Non Resectable, Recurrent Gynaecologic or Digestive Pelvic Cancer
Status: COMPLETED
Conditions: Gynaecologic or Digestive Pelvic Cancer
Interventions: DRUG: Isolated pelvis perfusion|RADIATION: radiotherapy|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Patch for Relief of Pain During Epidural Placement in Laboring Patients
Status: WITHDRAWN
Conditions: Pregnant|Labor
Interventions: DRUG: 5% lidocaine patch|DRUG: placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cassia Cinnamon for Glucose Uptake in Young Women
Status: COMPLETED
Conditions: Insulin Resistance|Impaired Glucose Tolerance|Prediabetes
Interventions: DIETARY_SUPPLEMENT: Cassia cinnamon|PROCEDURE: 50 minutes exercise|DIETARY_SUPPLEMENT: Cellulose Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Restricted Dietary of AGEs on the Glycemic Control, Oxidative Stress and Inflammation
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: OTHER: AGEs restricted diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trans-Artery/Intra-Tumor Infusion of Checkpoint Inhibitors Plus Chemodrug for Immunotherapy of Advanced Solid Tumors
Status: RECRUITING
Conditions: Hepatocarcinoma|Lung Cancer|Melanoma|Renal Cancer|Head and Neck Cancer|Pancreas Cancer|Ovarian Cancer|Colo-rectal Cancer|Cervical Cancer|Breast Cancer
Interventions: DRUG: Checkpoint inhibitor (CPI) such as Pembrolizumab plus chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic and Prognostic Biomarkers of Transplant Dysfunction in the Context of Lung Transplantation
Status: RECRUITING
Conditions: Lung Transplant Rejection|Lung Transplant Failure|Lung Transplant; Complications|Lung Transplant Failure and Rejection
Interventions: OTHER: Collection of biological samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Treatment for Mycobacterium Avium Complex (MAC) Infection in HIV-Infected Patients
Status: COMPLETED
Conditions: Mycobacterium Avium-intracellulare Infection|HIV Infections
Interventions: DRUG: Ethambutol hydrochloride|DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Monitoring of cfDNA by ddPCR in Non-small Cell Lung Cancer Treated by Immunotherapy.
Status: RECRUITING
Conditions: NSCLC|IMMUNOTHERAPY|QUANTIFICATION OF CELL-FREE DNA
Interventions: GENETIC: Molecular monitoring by quantification of cell-free DNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Long-Term Electrical Stimulation on LES Pressure and Esophageal Acid Exposure in Patients With GERD
Status: UNKNOWN
Conditions: Gastroesophageal Reflux Disease
Interventions: DEVICE: EndoStim LES Stimulation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy of TQB3823 Combined With Abiraterone and Prednisone in Metastatic Castration-resistant Prostate Cancer Patientsprednisone Acetate Tablets in Patients With Metastatic Castration-resistant Prostate Cancer
Status: TERMINATED
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: TQB3823 tablets|DRUG: Abiraterone acetate tablets|DRUG: prednisone acetate tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/Ib Study of NIZ985 Alone and in Combination With Spartalizumab
Status: TERMINATED
Conditions: In Escalation: All Patients With Solid Tumors and Lymphoma|In Expansion: Melanoma, Non-small Cell Lung Cancer
Interventions: DRUG: NIZ985|DRUG: Spartalizumab|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exercise Practices on Hyperactivity Levels in Children With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Autism
Interventions: OTHER: classical physical therapy program|OTHER: exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety and Biological Activity of ATYR1940 in Participants With Limb Girdle Muscular Dystrophy 2B (LGMD2B) and Facioscapulohumeral Muscular Dystrophy (FSHD)
Status: COMPLETED
Conditions: Limb-Girdle Muscular Dystrophies|Facioscapulohumeral Muscular Dystrophy
Interventions: BIOLOGICAL: ATYR1940|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transciptomic Modification Induced by miRNAs in Endometrial Fluid
Status: COMPLETED
Conditions: MicroRNA in Endometrial Fluid
Interventions: PROCEDURE: Endometrial fluid aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Axillary Phonophoresis Versus Post Isometric Facilitation in the Treatment of Shoulder Adhesive Capsulitis
Status: NOT_YET_RECRUITING
Conditions: Adhesive Capsulitis of Shoulder
Interventions: OTHER: Axillary Diclofenac phonophoresis|OTHER: Post isometric facilitation|OTHER: Traditional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tele-yoga Program in COPD and Heart Failure
Status: COMPLETED
Conditions: Yoga|COPD|Congestive Heart Failure
Interventions: BEHAVIORAL: Yoga Program at home using internet technology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation
Status: RECRUITING
Conditions: Relapsed or Refractory Acute Myeloid Leukemia (AML)|Untreated AML|Other IDH1-mutated Positive Hematologic Malignancies|Myelodysplastic Syndromes
Interventions: DRUG: AG-120
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Reslizumab (3.0 mg/kg) in the Reduction of Clinical Asthma Exacerbations in Patients (12-75 Years of Age) With Eosinophilic Asthma
Status: COMPLETED
Conditions: Eosinophilic Asthma
Interventions: DRUG: Reslizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Micropulse 577 nm Laser Photocoagulation Versus Conventional 532 nm Laser Photocoagulation for Diabetic Macular Oedema
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: DEVICE: Micropulse 577 nm yellow diode laser|DEVICE: 532 nm green diode laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Trial of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab in Patients With Newly Diagnosed PD-L1 CPS Positive Resectable Stage 3-4 Oral Cavity Squamous Cell Carcinoma (OCSCC).
Status: RECRUITING
Conditions: Squamous Cell Carcinoma|Oral Cavity Squamous Cell Carcinoma
Interventions: DRUG: Tiragolumab|DRUG: Atezolizumab|BEHAVIORAL: Standard of Care|BEHAVIORAL: Questionnaires|RADIATION: Cisplatin|RADIATION: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QUILT-3.005: A Study of ALT-803 in Patients With Relapsed or Refractory Multiple Myeloma
Status: UNKNOWN
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: BIOLOGICAL: ALT-803
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Sequential Treatment of Ropeginterferon Alfa-2b (P1101) and Anti-PD1 in Interferon-Naive Adults With Chronic Hepatitis B or D Infection
Status: UNKNOWN
Conditions: Chronic Hepatitis B Infection|Chronic Hepatitis D Infection
Interventions: DRUG: P1101 + Nivolumab + Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Toxicity of Paclitaxel, Cisplatin Combined With Sindilimab in NACT for Locally Advanced Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer|Chemotherapy Effect|Programmed Cell Death 1 Receptor / Antagonists & Inhibitors|Neoadjuvant Therapy
Interventions: DRUG: Sindilimab +paclitaxel+ cisplantin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Safety of Post-surgical Analgesics in Children With Obstructive Sleep Apnea
Status: UNKNOWN
Conditions: Pediatric Obstructive Sleep Apnea Syndrome
Interventions: DRUG: Morphine|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep, Diabetic Retinopathy and Melatonin
Status: RECRUITING
Conditions: Diabetes Mellitus|Diabetic Retinopathy
Interventions: DRUG: Melatonin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Beetroot Juice Ingestion Effects on Field Hockey Performance.
Status: COMPLETED
Conditions: Nitrates|Hockey
Interventions: DIETARY_SUPPLEMENT: Beetroot juice|DIETARY_SUPPLEMENT: Beetroot juice placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Protein Diet Versus Normal Protein Diet in Treating Patients With Minimal Hepatic Encephalopathy
Status: TERMINATED
Conditions: Liver Cirrhosis
Interventions: DIETARY_SUPPLEMENT: High protein diet|DIETARY_SUPPLEMENT: Normal protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Study of STX-478 as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
Status: RECRUITING
Conditions: Breast Cancer|Gynecologic Cancer|HNSCC|Solid Tumors, Adult
Interventions: DRUG: STX-478|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacodynamic, Efficacy and Safety of SHR-1703 in Asthma Patients With Eosinophil Phenotype
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma With Eosinophilic Phenotype
Interventions: DRUG: SHR-1703|DRUG: SHR-1703 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Dose Study of TRN-157 in Healthy Subjects
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: TRN-157|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CD19-targeted CAR T Cell Autotransfusion for the Treatment of Recurrent/Refractory B-cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma in Children With CD19+
Status: RECRUITING
Conditions: B Lymphocytic Leukemia|B Lymphoblastic Lymphoma
Interventions: DEVICE: CAR T cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Hair Transplantation Compared With Hypodermic Needle Irritation in Alopecia Areata
Status: TERMINATED
Conditions: Alopecia Areata|Alopecia|Balding
Interventions: PROCEDURE: Hair transplantation|PROCEDURE: Hypodermic needle irritation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radical Colorectal Resection and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Locally Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Malignant Neoplasm of Colorectum
Interventions: PROCEDURE: Hyperthermic intraperitoneal chemotherapy (HIPEC)|PROCEDURE: Radical colorectal resection|DRUG: Oxaliplatin , Capecitabine|DRUG: Normal saline , Cisplatin , 5-Fu
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness, Safety, and Health-Related Outcomes of NUEDEXTA® in Nursing Home Patients With Pseudobulbar Affect (PBA)
Status: TERMINATED
Conditions: Pseudobulbar Affect (Involuntary Laughing and/or Crying)
Interventions: DRUG: NUEDEXTA®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lapatinib Study for Children and Adults With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors
Status: COMPLETED
Conditions: Neurofibromatosis 2|Vestibular Schwannoma
Interventions: DRUG: Lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of Surfactant Booster Prophylaxis For Ventilated Preterm Neonates
Status: COMPLETED
Conditions: Respiratory Distress Syndrome|Bronchopulmonary Dysplasia
Interventions: DRUG: Infasurf
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sarilumab Effect on the Pharmacokinetics of Simvastatin
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: sarilumab SAR153191 (REGN88)|DRUG: simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Using Video for Triage of Children With Fever at the Medical Helpline 1813 in Copenhagen, Denmark
Status: COMPLETED
Conditions: Fever|Telemedicine|Pediatrics|Triage
Interventions: OTHER: Video triage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of taVNS on Abdominal Pain and Other Symptoms in Constipation-predominant Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Constipation-predominant Irritable Bowel Syndrome|Abdominal Pain
Interventions: DEVICE: taVNS|DEVICE: sham-taVNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Isavuconazole in Preventing Invasive Fungal Infections in Adult Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome and Neutropenia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome|Neutropenia
Interventions: DRUG: Isavuconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mechanism Of Stent Thrombosis (MOST) Study
Status: COMPLETED
Conditions: Coronary Artery|Stent Thrombosis|Platelet|Thrombus
Interventions: DEVICE: OCT guided PCI|DRUG: OCT guided medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: StrataGraft™ Skin Tissue (Human Donor Skin) In The Surgical Management Of Complex Skin Defects
Status: COMPLETED
Conditions: Third Degree Burn|Burns|Wound Infection|Degloving Injury
Interventions: BIOLOGICAL: StrataGraft Skin Tissue|PROCEDURE: Cadaver allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Basic Knowledge of CPR Among Close Relatives of Heart Patients-check Status Quo and Attemp to Establish a Potential Plan to Implement This Knowledge
Status: COMPLETED
Conditions: Cardiopulmonary Resuscitation
Interventions: BEHAVIORAL: course for learning CPR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A One-Year Study To Evaluate The Effects And Safety Of CP-690,550 In Patients With Moderate To Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: CP-690,550|DRUG: CP-690,550|DRUG: Placebo/CP-690,550|DRUG: Placebo/CP-690,550
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Intranasal Oxytocin on Fear Processing in Naturalistic Contexts
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: intranasal Oxytocin(24IU)|DRUG: intranasal Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Multiple Doses of AbGn-168H by Intravenous Infusion in Patients With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Moderate to Severe Chronic Plaque Psoriasis
Interventions: BIOLOGICAL: AbGn-168H|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Locally Administered Clodronate in the Prevention of Aseptic Implant Loosening
Status: COMPLETED
Conditions: Hip Arthrosis
Interventions: DRUG: Clodronate|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomized Multicentre Study to Compare Crinone 8% Once Daily Versus Other Vaginal Progesterone.
Status: UNKNOWN
Conditions: IVF - Luteal Phase Support After Embryo Transfer
Interventions: DRUG: progesterone|DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Dose Flu Vaccine in Treating Children Who Have Undergone Donor Stem Cell Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic Cell Transplantation Recipient|Malignant Neoplasm|Influenza
Interventions: BIOLOGICAL: Trivalent Influenza Vaccine|BIOLOGICAL: Quadrivalent Influenza Vaccine|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Lateral Cord Magnetic Stimulation For Refractory Spastic Cerebral Palsy
Status: RECRUITING
Conditions: Spastic Cerebral Palsy|Dysarthria
Interventions: DEVICE: Magnetic Spinal Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Prophylaxis Treatment & Characterizing Efficacy, Safety, & PK Of B-Domain Deleted Recombinant FVIII
Status: COMPLETED
Conditions: Hemophilia A
Interventions: BIOLOGICAL: Moroctocog alfa (AF-CC)|BIOLOGICAL: Moroctocog alfa (AF-CC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Inhaled Insulin in Patients With Diabetes and Asthma or COPD
Status: COMPLETED
Conditions: Diabetes Mellitus|Asthma|Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Human Insulin Inhalation Powder|DRUG: injected insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Response-guided Treatment of HER2 Positive Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Early-Stage Breast Carcinoma|HER-2 Positive Breast Cancer
Interventions: DRUG: docetaxel + trastuzumab sc + pertuzumab|DRUG: trastuzumab emtansin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Intravenous Hydrocortisone in Sepsis
Status: RECRUITING
Conditions: Sepsis Severe|Shock, Septic
Interventions: DRUG: Early hydrocortisone|DRUG: Normal saline placebo|DRUG: Open-label hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the QoR of PECS Block and GA in Breast-conserving Surgery With Sentinel Lymph Node Biopsy
Status: COMPLETED
Conditions: Breast Cancer|Pectoral Nerves Block|Breast-Conserving Surgery|Sentinel Lymph Node Biopsy
Interventions: COMBINATION_PRODUCT: PECS II combined with intercostal nerve blockade;|COMBINATION_PRODUCT: General anesthesia with laryngeal mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Efficacy of HL036 in Subjects With Dry Eyes
Status: COMPLETED
Conditions: Dry Eye
Interventions: BIOLOGICAL: HL036 ophthalmic solution|OTHER: Placebo vehicle solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Real-world Effectiveness and Cost-effectiveness of Leading Inhaled Corticosteroids in Asthma Management
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Extra-fine hydrofluoroalkane-beclomethasone dipropionate|DRUG: Extra-fine hydrofluoroalkane-beclomethasone dipropionate|DRUG: Fluticasone propionate|DRUG: Beclomethasone dipropionate|DRUG: fluticasone propionate|DRUG: Chlorofluorocarbon beclomethasone dipropionate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gene Therapy for X-linked Severe Combined Immunodeficiency (SCID-X1)
Status: UNKNOWN
Conditions: X-linked Severe Combined Immunodeficiency
Interventions: GENETIC: Single infusion of autologous CD34+ cells transduced with the self-inactivating (SIN) gammaretroviral vector pSRS11.EFS.IL2RG.pre
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Oral cMET Inhibitor INC280 in Patients With EGFR Wild-type (wt), Advanced Non-small Cell Lung Cancer (NSCLC) (Geometry Mono-1)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Capmatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Metal on Metal Total Hip Arthroplasty and Metal on Metal Total Hip Resurfacing.
Status: COMPLETED
Conditions: Arthroplasty|Replacement|Hip
Interventions: DEVICE: THA|DEVICE: HR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Long Term Safety and Efficacy of Biphasic Insulin Aspart 30 in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 30
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Baloxavir and Oseltamivir for the Treatment of Severe Influenza Infection in Immunocompromised Patients
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Influenza
Interventions: DRUG: Baloxavir Marboxil|DRUG: Oseltamivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Single- and Multi-Dose, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered ALN-TTRSC (Revusiran) in Healthy Volunteers
Status: COMPLETED
Conditions: TTR-mediated Amyloidosis
Interventions: DRUG: ALN-TTRSC (revusiran)|DRUG: Sterile Normal Saline (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Community Health Program for the Prevention of Type 2 Diabetes and Other Cardio-metabolic Risk Factors in Adults: Districts of Barranquilla and Bogota, Colombia - January 2017 - December 2019
Status: UNKNOWN
Conditions: Prediabetic State
Interventions: BEHAVIORAL: Intervention_ S|BEHAVIORAL: Intervention_ I|BEHAVIORAL: Intervention_ C
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Dexmedetomidine on Postoperative Analgesia
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Ropivacaine plus dexmedetomidine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neural Control and Cardiac-Vascular Function in Women With PTSD (VA Psychological Assessment)
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: Exercise training and healthy eating (overseen by IEEM research team)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zinc Versus Multivitamin Micronutrient Supplementation in the Setting of COVID-19
Status: COMPLETED
Conditions: Healthy|Health Care Worker Patient Transmission|Aging
Interventions: DIETARY_SUPPLEMENT: PreserVision AREDS formulation soft gels or tablets|DIETARY_SUPPLEMENT: Multivitamin with 11mg of zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Autologous Stem Cell Transplantation for Crohn's Disease
Status: RECRUITING
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: autologous CD34-selected peripheral blood stem cells transplant|DRUG: Alemtuzumab|DRUG: ATG|DRUG: Melphalan|DRUG: Thiotepa|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: G-CSF|DRUG: Mesna
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin Plus Capecitabine in Treating Patients With Metastatic or Recurrent Solid Tumor
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: capecitabine|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Safety and Pharmacokinetics of RDG-17012 Capsule and Pradaxa® Capsule in Healthy Male Volunteers
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: RDG-17012 Capsule|DRUG: Dabigatran Etexilate Mesylate 150 MG Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Tenecteplase (TNK) in Acute Ischemic Stroke (TNK-S2B)
Status: TERMINATED
Conditions: Stroke
Interventions: DRUG: tenecteplase|DRUG: tissue plasminogen activator, tPA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of DA-2802 in Chronic Hepatitis B Patients
Status: COMPLETED
Conditions: Hepatitis B， Chronic
Interventions: DRUG: DA-2802|DRUG: Viread®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MDR TB, Levofloxacin, Multi-Drug-Resistant Pulmonary Tuberculosis
Status: COMPLETED
Conditions: Tuberculosis, Pulmonary
Interventions: DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VitaFlowTM II Transcatheter Aortic Valve System Study
Status: NOT_YET_RECRUITING
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: VitaFlow II Transcatheter Aortic Valve System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Wrist Ankle Acupuncture on Post-Total Hip Arthroplasty Pain
Status: COMPLETED
Conditions: Pain, Postoperative|Hip Osteoarthritis|Hip Fractures|Hip Injuries
Interventions: PROCEDURE: wrist ankle acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Investigation to Assess the Performance of a Polyurethane Condom Versus a Latex Condom in Healthy Monogamous Couples
Status: COMPLETED
Conditions: Control of Pregnancy|Prevention of Sexually Transmitted Infections
Interventions: DEVICE: Polyurethane (PU) condom|DEVICE: Natural Rubber Latex (NRL) condom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cabazitaxel - PF Induction Chemotherapy
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Cabazitaxel 10mg/m2|DRUG: Cabazitaxel 12.5mg/m2|DRUG: Cabazitaxel 15mg/m2|DRUG: Cabazitaxel 17.5mg/m2|DRUG: Cabazitaxel 20mg/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FLEX Vessel Prep Prior to Angioplasty in Native Arteriovenous Fistulae (AVF)
Status: COMPLETED
Conditions: Arteriovenous Fistula Stenosis
Interventions: DEVICE: FLEX Vessel Prep System|DEVICE: Angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Intrauterine Growth Restriction With Low Molecular Heparin.
Status: COMPLETED
Conditions: Intrauterine Growth Restriction
Interventions: DRUG: Low molecular weight heparin|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilocarpine in Preventing Mucositis and Dry Mouth in Patients Receiving Radiation Therapy for Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Oral Complications
Interventions: DRUG: pilocarpine hydrochloride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Targeting Metastatic Breast Cancers by Alkaline Glucosodiene Molecules Via a Metabolic Pathway Phase I Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: TNBC - Triple-Negative Breast Cancer
Interventions: DRUG: Alkaline Glucosodiene Molecules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydrochloorthiazide and Hypernatriaemie
Status: COMPLETED
Conditions: Hypernatraemia
Interventions: DRUG: Hydrochloorthiazide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Recombinant Monoclonal Antibody Against Human Epidermal Growth Factor Receptor Injection
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: recombinant monoclonal antibody against human epidermal growth factor receptor injection (HS627)|DRUG: Perjeta ®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vaccine Therapy in Treating Patients With Advanced Adenocarcinoma of the Prostate (Prostate Cancer)
Status: TERMINATED
Conditions: Adenocarcinoma of the Prostate|Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: BIOLOGICAL: recombinant fowlpox-prostate specific antigen vaccine|BIOLOGICAL: recombinant vaccinia prostate-specific antigen vaccine|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Autologus Bone Marrow Mesenchymal Stem Cells in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: Autologous Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of VSL#3 Probiotic Preparation on the Bile Acid Metabolism in Patients With Inflammatory Bowel Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Crohn Disease|Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: VSL#3 (Original De Simone formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigative Trial of Interferon Alpha-2b To Shrink Cancer of the Eye
Status: WITHDRAWN
Conditions: Ocular Melanoma
Interventions: DRUG: Pegylated Interfon Alpha 2B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of S 47445 Versus Placebo as Adjunctive Treatment in Depressed Patients Not Fully Recovered From Depressive Symptoms With a Current Antidepressant Treatment
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: S47445 15mg|DRUG: S47445 50mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effects of Rifampicin on the Pharmacokinetics of Aleglitazar in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: aleglitazar|DRUG: rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Urodynamics and Clinical Factors That Are Associated With Bladder Over-sensitivity
Status: UNKNOWN
Conditions: Overactive Bladder Syndrome|Bladder Outlet Obstruction|Benign Prostate Enlargement|Stress Incontinence (Female) (Male)|Bladder Disease
Interventions: OTHER: IPSS questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p