pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Impact of Pumpkin Seed Oil Supplementation on Hemodialysis Patients
Status: NOT_YET_RECRUITING
Conditions: Hemodialysis Patients
Interventions: DRUG: Pumpkin Seed Oil " Ronkin®, KMT PHARMA, Egypt. "
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Harmony & Health: A Culturally Adapted Mindbody Intervention to Reduce Sitting Time and Improve Psychosocial Wellbeing in Black Adults
Status: RECRUITING
Conditions: Psychosocial
Interventions: BEHAVIORAL: Harmony & Health program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical & Biochemical Effect of Atorvastatin in Nano Particles Gel in Periodontitis Treatment
Status: COMPLETED
Conditions: Periodontitis
Interventions: DRUG: Atorvastatin Calcium|DRUG: Atorvastatin Calcium|OTHER: Scaling and debridement only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Second-line Treatment With Apatinib in Patients With Advanced Intrahepatic Cholangiocarcinoma
Status: COMPLETED
Conditions: Intrahepatic Cholangiocarcinoma|Second-line Treatment
Interventions: DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics for Reduction of Infections With Clostridium Difficile in Critically Ill Patients
Status: TERMINATED
Conditions: Clostridium Difficile Colonisation|Impact of Enteral Probiotics on Certain Lab Parameters
Interventions: DIETARY_SUPPLEMENT: L. plantarum 299 and L. plantarum 299v (+maltodextrin)|OTHER: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Double-blind, Placebo-controlled Study of Antidepressant Augmentation With Agomelatine
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Agomelatine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacokinetics of Enasidenib (CC-90007) in Subjects With Moderate and Severe Hepatic Impairment.
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Enasidenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Imaging Exploration of Ocular Angiogenic Activity and Evaluation of Its Interest in the Therapeutic Follow-up of Patients With AMD (Age-related Macular Degeneration)
Status: RECRUITING
Conditions: Age Related Macular Degeneration
Interventions: OTHER: radiopharmaceutical
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Analysis of Filmed Sequences for the Assessment of Discomfort in Atopic Dermatitis of Infants Under 6 Months of Age
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: OTHER: Filmed consultation with a dermatologist
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Deferasirox in Patients With Myelodysplastic Syndrome and Transfusion-dependent Iron Overload
Status: COMPLETED
Conditions: Myelodysplastic Syndromes|Transfusion Dependent Iron Overload
Interventions: DRUG: ICL670/Deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Q-1802 Combined With XELOX in Gastrointestinal Tumors
Status: RECRUITING
Conditions: Gastroesophageal Junction (GEJ) Adenocarcinoma
Interventions: DRUG: Q-1802 Injection,Oxaliplatin Injection,Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting Oxidative Stress in Chronic Beryllium Disease
Status: COMPLETED
Conditions: Chronic Beryllium Disease
Interventions: DRUG: Mesalamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing the Burden of Chronic Psychotic Disorders in Tanzania (CAPACITY)
Status: COMPLETED
Conditions: Schizophrenia|Medication Nonadherence|Schizo Affective Disorder
Interventions: BEHAVIORAL: Customized Adherence Enhancement|DRUG: Haloperidol Decanoate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Antioxidants in the Reduction of Oxidative Stress in Infertile Patients
Status: COMPLETED
Conditions: Infertility|Oligoasthenozoospermia|Male
Interventions: COMBINATION_PRODUCT: Antioxidant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PD-1 Antibody and Lenvatinib Plus TACE-HAIC for Potential Resectable HCC: a Single-arm, Phase 2 Clinical Trial
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: PD-1 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biobank and Brain Health in Bordeaux.
Status: RECRUITING
Conditions: Brain|Aging|Cognitive Aging|Immunosenescence|Mental Processes|Mental Disorders|Neurocognitive Disorders|Cognition|Brain Diseases|Dementia|Alzheimer Disease|Mental Health|Behavioral Symptoms|Depression|Anxiety
Interventions: OTHER: Questionnaires|OTHER: Fasting blood sampling.|OTHER: Saliva collection and nasal or nasopharyngeal swab|OTHER: Urine samples|OTHER: Hair and a tonenail (or hand nail) sampling|OTHER: Nasal microbiota|OTHER: Measurements|OTHER: Neuroimaging|OTHER: Medical visit
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Magrolimab and Pembrolizumab in Relapsed or Refractory Classic Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Hodgkin Lymphoma|Classic Hodgkin Lymphoma|Relapsed Classical Hodgkin Lymphoma|Refractory Classic Hodgkin Lymphoma
Interventions: DRUG: Magrolimab|DRUG: Pembrolizumab|PROCEDURE: PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Moderate Versus Deep Neuromuscular Blockade on Enhanced Recovery After Bariatric Anesthesia
Status: UNKNOWN
Conditions: Bariatric Surgery Candidate
Interventions: DEVICE: Neuromuscular transmission monitoring (NMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of Alcohol Swabs for Preventing Infections During Vaccination
Status: UNKNOWN
Conditions: Skin Infection
Interventions: DRUG: Alcohol|DRUG: No alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of tDCS on Internet Game Addiction
Status: COMPLETED
Conditions: Addiction|Internet Gaming Disorder
Interventions: DEVICE: tDCS with real stimulation|DEVICE: tDCS with sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Transdermal Therapeutic System (TTS)-Fentanyl in Thai Participants With Chronic Non-Malignant Pain
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: TTS-Fentanyl|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Urinary Bladder Wall Involvement in Abnormally Invasive Placenta (AIP) by 3D Ultrasonography
Status: COMPLETED
Conditions: Placenta Accreta
Interventions: DIAGNOSTIC_TEST: 3 dimensional ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MRI-based Neuroimaging Predictors of Clinical Improvements Following Therapy in Children With Cerebral Palsy
Status: UNKNOWN
Conditions: Brain Injury, Chronic|Cerebral Palsy
Interventions: BEHAVIORAL: Occupational therapy|OTHER: Occupational therapy puls acupuncture and massage methods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Bevacizumab and Endothelium Dependent Vasodilation
Status: COMPLETED
Conditions: Hypertension|Cancer|Endothelial Dysfunction
Interventions: DRUG: Acetylcholine|DRUG: Nitroprusside|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Study of TS-1 or TS-1 + PSK for Gastric Cancer Patients
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Tegafur-gimeracil-oteracil potassium (TS-1)|DRUG: Krestin (PSK)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ventilatory Support to Improve Exercise Training in High Level Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DEVICE: Non-invasive Ventilation(NIV)|DEVICE: Sham Non-invasive ventilation(NIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ixabepilone in Treating Young Patients With Refractory Solid Tumors
Status: COMPLETED
Conditions: Adult Rhabdomyosarcoma|Adult Synovial Sarcoma|Alveolar Childhood Rhabdomyosarcoma|Childhood Synovial Sarcoma|Embryonal Childhood Rhabdomyosarcoma|Previously Treated Childhood Rhabdomyosarcoma|Recurrent Adult Soft Tissue Sarcoma|Recurrent Childhood Rhabdomyosarcoma|Recurrent Childhood Soft Tissue Sarcoma|Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Recurrent Neuroblastoma|Recurrent Osteosarcoma|Recurrent Wilms Tumor and Other Childhood Kidney Tumors
Interventions: DRUG: ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Lumbar Interbody Fusion With MatriTMBONE Associated With Autologous Bone Marrow
Status: COMPLETED
Conditions: Degenerative Osteoarthritis|Degenerative Lumbar Vertebra
Interventions: PROCEDURE: The Transforaminal Lumbar Interbody Fusion (TLIF) surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Within-Subject Cross-Over Comparison Between Immediate Release and Extended Release Adderall
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Adderall ® Immediate Release|DRUG: Adderall XR ®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of MT-1303 in Systemic Lupus Erythematosus Patients
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: MT-1303 Low dose|DRUG: MT-1303 High dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile App Psychological Interventions for Family Dementia Caregivers
Status: ACTIVE_NOT_RECRUITING
Conditions: Family Caregivers
Interventions: BEHAVIORAL: Mentalizing Imagery Therapy and caregiver skills mobile application|BEHAVIORAL: Caregiver skills mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects Of of Pursed Lip Breathing and Coordinated Breathing in Adult Patients With COPD
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: pursed lip breathing techniques|OTHER: coordinated breathing technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Family Colorectal Cancer Awareness and Risk Education Project (Family CARE Project)
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: TeleCARE|BEHAVIORAL: Pamphlet intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tofacitinib Associated With Meglumine Antimoniate in Cutaneous Leishmaniasis
Status: NOT_YET_RECRUITING
Conditions: Cutaneous Leishmaniasis, American
Interventions: DRUG: Oral tofacitinib|DRUG: Parenteral meglumine antimoniate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Possible Differences in HCC Course Depending on DAA Treatment
Status: UNKNOWN
Conditions: Carcinoma, Hepatocellular|Hepatitis C Virus Infection, Response to Therapy of|Drug Effect|Drug Side Effect|Hepatitis C, Chronic|Liver Cirrhosis
Interventions: DRUG: Direct Acting Antivirals
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot Study of High-Dose, Intravenous Ascorbic Acid (Vitamin C) to Treat Hepatitis C
Status: TERMINATED
Conditions: Hepatitis C
Interventions: DIETARY_SUPPLEMENT: ascorbic acid (vitamin C)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Genicular Nerve Block in Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DRUG: Genicular nerve block with lidocaine|DRUG: Genicular nerve block with saline|DRUG: Genicular nerve block with dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Transcranial Direct Current Stimulation on Cognitive Side Effects of Electroconvulsive Therapy
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: DEVICE: transcranial magnetic stimulation|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Effectiveness of Supervised, Video-based and Home-based Resistance Exercise Program in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: OTHER: Home based exercise|OTHER: Video-based resistive exercise|OTHER: Supervised resistive exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Do Antibiotics Prevent Anal Fistulae Formation?
Status: COMPLETED
Conditions: Anal Fistula
Interventions: DRUG: Amoxicillin-Clavulanate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy With or Without Amifostine in Treating Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or Hodgkin's Disease Undergoing Stem Cell Transplantation
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Amifostine|DRUG: DHAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Proximal and Distal Robot-assisted Therapy Combined With Functional Training
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: proximal robot-assisted therapy|DEVICE: distal robot-assisted therapy|BEHAVIORAL: individualized intensive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Midazolam and Remifentanil During Dialysis Access Procedures
Status: COMPLETED
Conditions: Sedative Adverse Reaction|Analgesic Adverse Reaction|Midazolam Adverse Reaction|Adverse Reaction to Drug|Patient Satisfaction|Chronic Kidney Diseases|Arteriovenous Fistula
Interventions: DRUG: Midazolam intravenous injection|DRUG: Remifentanil intravenous bolus dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Does in Vivo Culture of Pre-cleavage Stage Embryo Reduce the Incidence of Aneuploidy?
Status: TERMINATED
Conditions: Infertility|Reproductive Sterility
Interventions: DEVICE: AneVivo (Medical device for in vivo culture of embryos)|OTHER: comparator for embryo culture in vitro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Valacyclovir Plus Celecoxib for Post-Acute Sequelae of SARS-CoV-2
Status: RECRUITING
Conditions: Long COVID|PASC Post Acute Sequelae of COVID 19
Interventions: DRUG: Valacyclovir celecoxib dose 1|DRUG: Valacyclovir celecoxib dose 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Dose Escalation Safety Study of RetinoStat in Advanced Age-Related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Age Related Macular Degeneration
Interventions: DRUG: Subretinally injected RetinoStat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Preliminary Effectiveness of a CHW Training Program to Support African American and Latino Male Caregivers
Status: COMPLETED
Conditions: Caregiver Burnout
Interventions: OTHER: Intervention to Help Orient Men to Excel (IN-HOME)|OTHER: AARP's English "Care at Home" resource webpage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Endoscopic Ultrasound-guided Versus Surgical Gastroenterostomy for Malignant Gastric Outlet Obstruction
Status: UNKNOWN
Conditions: Malignant Gastric Outlet Obstruction
Interventions: PROCEDURE: EUS-guided gastroenterostomy (EUS-GE)|PROCEDURE: Laparoscopic gastroenterostomy (LGE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Therapeutic Strategies on Regulatory T Cells in Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Tacrolimus + Methylprednisolone|DRUG: Tacrolimus + Everolimus + Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Of Clodronate 200 Mg/4 Ml I.M. Solution With 1% Lidocaine Every Other Week Vs Clodronate 100 Mg/3,3ml I.M. Solution With 1% Lidocaine Once-Week In A 1-Year Treatment Period Of Women With Postmenopausal Osteoporosis
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: disodium clodronate 200 mg/4 ml with 1% lidocaine|DRUG: Disodium clodronate 100 mg/3,3 ml with 1% lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Commercial Anti-Plaque Products and Oral Rinse
Status: COMPLETED
Conditions: Dental Plaque
Interventions: DRUG: Fluoride|DRUG: Chlorhexidine digluconate|DRUG: Fluoride, triclosan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gastric Assessment of Pediatric Patients Undergoing Surgery
Status: RECRUITING
Conditions: Fasting|Delayed Gastric Emptying|Aspiration Pneumonia|Respiratory Aspiration of Gastric Content
Interventions: DIAGNOSTIC_TEST: Gastric Ultrasound Baseline Scans|DIAGNOSTIC_TEST: Acetaminophen Absorption Test (AAT)|DIAGNOSTIC_TEST: Gastric Ultrasound Serial Scans
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: First-in-Human Single Ascending Subcutaneous (s.c.) Dose and Single Oral Dose of GLPG0187
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG0187|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Alglucosidase Alfa Temporary Access Program
Status: APPROVED_FOR_MARKETING
Conditions: Glycogen Storage Disease Type II (GSD-II)|Pompe Disease (Late-Onset)|Acid Maltase Deficiency Disease|Glycogenosis 2
Interventions: BIOLOGICAL: alglucosidase alfa (recombinant human acid alpha-glucosidase [rhGAA])
Study Type: EXPANDED_ACCESS
Clinical trial: Effects of Cannabis on Cognition and Endocannabinoid Levels in Bipolar Disorder Patients and Healthy Volunteers
Status: TERMINATED
Conditions: Bipolar Disorder
Interventions: DRUG: Dronabinol|DRUG: Epidiolex|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dual Field PEMF Therapy in Lower Extremity Painful Diabetic Distal Symmetric Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathy Peripheral
Interventions: DEVICE: Active Provant Therapy System|DEVICE: Inactive (sham) Provant Therapy System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Subthalamic Nucleus Gene Therapy for Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: GENETIC: Surgical infusion of AAV-GAD into the subthalamic nucleus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LP002 for the Treatment of Patients With Malignant Digestive System Neoplasms
Status: UNKNOWN
Conditions: Digestive System Neoplasms
Interventions: DRUG: LP002|DRUG: Cisplatin|DRUG: Fluorouracil|BIOLOGICAL: OH2 oncolytic virus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Home- vs. Gym-based Exercise Delivery Modes
Status: COMPLETED
Conditions: Vascular Stiffness|Cardiorespiratory Fitness
Interventions: BEHAVIORAL: Home-Based|BEHAVIORAL: Gym-Based
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of Sertraline vs. CBT for End-stage Renal Disease Patients With Depression {ASCEND}
Status: COMPLETED
Conditions: Depression|End Stage Renal Disease
Interventions: BEHAVIORAL: Engagement Interview|BEHAVIORAL: Cognitive Behavioral Therapy|DRUG: Antidepressant Drug Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OCR002-SP103 - Oral Immediate Release Study
Status: COMPLETED
Conditions: Cirrhosis
Interventions: DRUG: OCR-002 IR Oral Tablet|DRUG: OCR-002 Oral Solution|DRUG: OCR-002 IV Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Testosterone and Physical Function in HIV+ Men
Status: COMPLETED
Conditions: HIV Associate Weight Loss
Interventions: DRUG: Testosterone enanthate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Setmelanotide Phase 2 Treatment Trial in Participants With Rare Genetic Disorders of Obesity
Status: COMPLETED
Conditions: Genetic Obesity|Obesity|Obesity Due to Melanocortin 4 Receptor Deficiency
Interventions: DRUG: Setmelanotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Anabolic Effect Of Perioperative Nutrition With Insulin In Patients Undergoing CABG
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DIETARY_SUPPLEMENT: Amino acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acute Effects of Grape Seed Extract on Insulin Sensitivity and Oxidative Stress and Inflammation Markers.
Status: COMPLETED
Conditions: Polyphenolic Compounds and Metabolism
Interventions: DIETARY_SUPPLEMENT: Active Capsule|DIETARY_SUPPLEMENT: Placebo Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Single Versus Multi-Dose Oral and Intravenous Tranexamic Acid Patients at High Risk for Blood Transfusion After Spine Surgery
Status: RECRUITING
Conditions: Open Posterior Thoracolumbar Spinal Fusion Procedure
Interventions: DRUG: Tranexamic Acid Injectable Product (1000 mg intravenous bolus)|DRUG: Vitamin C 250 MG Oral Tablet|DRUG: Tranexamic Acid 650Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of the Safety and Efficacy of Cefdinir Oral Suspension Versus Amoxicillin/Clavulanate in Pediatric Subjects With Acute Otitis Media
Status: COMPLETED
Conditions: Acute Otitis Media
Interventions: DRUG: cefdinir (Omnicef)|DRUG: amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dutasteride to Treat Women With Menstrually Related Mood Disorders
Status: COMPLETED
Conditions: Premenstrual Syndrome|PMS|Healthy|Depression
Interventions: DRUG: Dutasteride|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Neuromuscular Reversal With Sugammadex on Postoperative Recovery Profile
Status: COMPLETED
Conditions: Postoperative Respiratory Condition
Interventions: DRUG: Sugammadex|DRUG: Neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Real-time Notification of Colonoscopic Optical Diagnosis on Patients' Anxiety and Depression After Polypectomy
Status: RECRUITING
Conditions: Colorectal Neoplasms|Colonic Polyp|Anxiety|Depression|Colonoscopy
Interventions: OTHER: Real-time endoscopic optical diagnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ASPIrin in Reducing Events in Dialysis ( ASPIRED )
Status: RECRUITING
Conditions: CKD (Chronic Kidney Disease) Stage 5D
Interventions: DRUG: Aspirin 100 mg Oral Tablet|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OPtical Diagnosis Training to Improve Dysplasia Characterisation in IBD
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Dysplasia Colon|Dysplasia, Crohn Disease-Associated|Polyp of Colon|Ulcerative Colitis|Crohn Colitis|Crohn Disease
Interventions: OTHER: Online self-learning training module|OTHER: Refresher training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Balance Exercises Performed With Different Visual Stimuli
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: Balance exercises with Virtual Reality Glasses|OTHER: Balance Exercises with Stroboscopic Glasses|OTHER: Balance Exercises with Visual-Based Metaphor Training|OTHER: Traditional Balance Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Insomnia Treatment on Metabolism in Patients With Depression
Status: COMPLETED
Conditions: Insomnia Chronic|Insomnia|Insomnia, Primary|Depression|Depressive Symptoms
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia (CBT-I)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: GW572016, An Oral Drug For Colorectal Cancer Patients Having Prior Therapy With 5-FU Plus CPT-11 And/Or Oxaliplatin
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerability, Safety, Pharmacokinetics and Efficacy of HS-10241 Single Agent or Combined With Apatinib in Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Cancer
Interventions: DRUG: HS-10241|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Novel Synthetic T2W MR Imaging and Spin Parameter Mapping Techniques for Screening Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Adenocarcinoma|Prostate Carcinoma
Interventions: PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Efficacy and Safety of GSK1358820 (Botulinum Toxin Type A) in Patients With Strabismus
Status: COMPLETED
Conditions: Strabismus
Interventions: DRUG: GSK1358820
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Steroid Injection With Exercise for Subacromial Bursitis
Status: RECRUITING
Conditions: Shoulder Bursitis
Interventions: OTHER: resistance exercise|DRUG: triamcinolone acetonide plus lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SMART Weight Loss Management
Status: COMPLETED
Conditions: Weight Loss
Interventions: BEHAVIORAL: Step 1 Treatment: APP|BEHAVIORAL: Step 1 Treatment: APP + Coaching|BEHAVIORAL: Step 2 Treatment Strategy: Modest Step-up|BEHAVIORAL: Step 2 Treatment Strategy: Vigorous Step-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Anlotinib Hydrochloride and Toripalimab in Subjects With Unresectable or Metastatic Undifferentiated Pleomorphic Sarcoma
Status: UNKNOWN
Conditions: Soft Tissue Sarcomas|Undifferentiated Pleomorphic Sarcoma
Interventions: DRUG: Anlotinib|DRUG: Toripalimab|PROCEDURE: Blood Draw|PROCEDURE: Tumor Specimen Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Auricular Acupressure for Appetite and Weight in Patients With Stage II-IV Gastric, Esophageal, and Pancreatic Cancer
Status: RECRUITING
Conditions: Clinical Stage II Esophageal Adenocarcinoma AJCC v8|Clinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8|Clinical Stage II Gastric Cancer AJCC v8|Clinical Stage III Esophageal Adenocarcinoma AJCC v8|Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC v8|Clinical Stage III Gastric Cancer AJCC v8|Clinical Stage IV Esophageal Adenocarcinoma AJCC v8|Clinical Stage IV Esophageal Squamous Cell Carcinoma AJCC v8|Clinical Stage IV Gastric Cancer AJCC v8|Stage II Pancreatic Cancer AJCC v8|Stage III Pancreatic Cancer AJCC v8|Stage IV Pancreatic Cancer AJCC v8
Interventions: PROCEDURE: Acupressure Therapy|OTHER: Best Practice|PROCEDURE: Biospecimen Collection|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study to Evaluate the Efficacy of the Dietary Supplement UROMANNOSA® in Women With Recurrent Lower Urinary Tract Infections
Status: SUSPENDED
Conditions: Lower Urinary Tract Infection
Interventions: DIETARY_SUPPLEMENT: Group (A)|DIETARY_SUPPLEMENT: Group (B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Role of Suppression of Endometriosis With Progestins Before IVF-ET
Status: COMPLETED
Conditions: IVF|Endometriosis|Pregnancy Rate|Progestins|GnRH-analogue
Interventions: DRUG: Dienogest|DRUG: leuprorelin acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CHECK Trial: A Comparison of Headache Treatment in the Emergency Department: Compazine Versus Ketamine
Status: TERMINATED
Conditions: Headache
Interventions: DRUG: Compazine|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiorespiratory Response During Whole Body Vibration Training in Patients With Chronic Lung Disease
Status: COMPLETED
Conditions: Chronic Obstructive Lung Disease (n=10)|Interstitial Lung Disease (n=10)
Interventions: OTHER: Whole body vibration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Short Term Aliskiren Treatment in Kidney Transplant Patients
Status: TERMINATED
Conditions: Kidney Disease|Kidney Failure, Chronic
Interventions: DRUG: Aliskiren|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparitive Study of Two Misoprostol Regimen in Early Pregnancy Termination
Status: COMPLETED
Conditions: Termination
Interventions: DRUG: Misoprostol 400 micrograms|DRUG: Misoprostol 800 micrograms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Augmented Reality to Support Cardiopulmonary Resuscitation
Status: NOT_YET_RECRUITING
Conditions: Cardiopulmonary Arrest|Resuscitation|Pediatric
Interventions: DEVICE: Augmented reality supportive tool|OTHER: Conventional method (AHA pocket reference card)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Immunogenicity and Safety Study of Allantoic Split Inactivated Seasonal Influenza Vaccine (VSI)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Allantoic Split Inactivated Seasonal flu Vaccine|BIOLOGICAL: VAXIGRIP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: MR Image Synthesis With Low Gadobutrol Dose and AI
Status: ENROLLING_BY_INVITATION
Conditions: Enhancing Brain Lesions
Interventions: DEVICE: SubtleGAD|DRUG: Gadobutrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of ES102 (OX40 Agonist) in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors|Neoplasms|Malignant Tumor
Interventions: DRUG: ES102
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Two Different 10.0% Benzoyl Peroxide Creams for Mild to Moderate Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Topical benzoyl peroxide 10.0% cream - Formulation 1|DRUG: Topical benzoyl peroxide 10.0% cream - Formulation 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Baby Iron Bioavailability Study
Status: COMPLETED
Conditions: Iron Bioavailability
Interventions: OTHER: Labeled iron salt Fe54|OTHER: Labeled iron salt Fe57|OTHER: Labeled iron salt Fe58
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Surgical TreAtment for Obesity Related Disease and Onco-Metabolic Surgery
Status: RECRUITING
Conditions: Gastric Cancer|Diabetes Mellitus, Type 2
Interventions: PROCEDURE: Long limb Roux-en-Y reconstruction after subtotal gastrectomy|PROCEDURE: Conventional Roux-en-Y reconstruction after subtotal gastrectomy|PROCEDURE: Billroth II reconstruction after subtotal gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Activation for Heroin Use in China: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Substance-Related Disorders|Mood Disorders|Behavioral Activation Treatment|Mental Disorders
Interventions: BEHAVIORAL: Treatment as usual|BEHAVIORAL: Chinese translated LETS ACT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lactobacillus-containing Cultured Milk Drink Alleviates Depression Score Among Adults With Irritable Bowel Syndrome
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome With Subthreshold Depression
Interventions: DIETARY_SUPPLEMENT: Lactobacillus containing cultured milk drink|DIETARY_SUPPLEMENT: Placebo cultured milk drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Unique Micro Water Jet Technology Device Versus Standard Debridement in the Treatment of Diabetic Foot
Status: RECRUITING
Conditions: Diabetic Foot Ulcer|Diabetic Foot
Interventions: OTHER: Medaxis Debritom+|OTHER: Sharp Surgical Debridement|OTHER: Additional Outer Dressing Application|OTHER: Offloading|OTHER: Fibracol Wound Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxygen Saturation Measurement With Pulse Oximetry and With Smart Phones and Smart Wearable
Status: NOT_YET_RECRUITING
Conditions: Oxygen Saturation Measurement
Interventions: OTHER: Oxgen saturation measurement with validated pulse oximetry|OTHER: Oxgen saturation measurement with smart electronics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Durvalumab and Tremelimumab With or Without High or Low-Dose Radiation Therapy in Treating Patients With Metastatic Colorectal or Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Carcinoma|Metastatic Lung Non-Small Cell Carcinoma|Stage IV Colorectal Cancer AJCC v7|Stage IV Lung Non-Small Cell Cancer AJCC v7|Stage IVA Colorectal Cancer AJCC v7|Stage IVB Colorectal Cancer AJCC v7
Interventions: BIOLOGICAL: Durvalumab|RADIATION: Radiation Therapy|BIOLOGICAL: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Safety of an HIV-1 Vaccine Given Intra-muscularly and Intra-nasally to Healthy Female Subjects
Status: COMPLETED
Conditions: HIV-1
Interventions: BIOLOGICAL: MYM-V101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PRospective Evaluation Comparing Initiation of Warfarin StrategiEs (PRECISE): Pharmacogenetic-guided Versus Usual Care
Status: WITHDRAWN
Conditions: Blood Coagulation Disorders
Interventions: DRUG: Warfarin Dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Exemestane Versus Anastrozole as First Line Hormone Therapy in Postmenopausal Metastatic Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Exemestane|DRUG: Anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Inhaled Therapies in the Treatment of Acute Symptoms Associated With COVID-19
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: inhaled beclametasone|DRUG: Inahaled beclomethasone / formoterol / glycopyrronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dabigatran Versus Warfarin After Mitral and/or Aortic Bioprosthesis Replacement and Atrial Fibrillation Postoperatively
Status: TERMINATED
Conditions: Primary Disease
Interventions: DRUG: Dabigatran|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetes Study of Linagliptin and Empagliflozin in Children and Adolescents (DINAMO)TM
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Metformin|DRUG: Insulin|DRUG: Placebo|DRUG: Linagliptin|DRUG: Empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-Blinded, Randomized Placebo Controlled Pilot Study Comparing the Efficacy and Safety of IncobotulinumtoxinA Versus Saline Injections to the Cheek Region in Patients With Rosacea
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: IncobotulinumtoxinA|DRUG: Bacteriostatic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Regional Brain Kinetics of the Positron Emission Tomography Ligand [18F]-JNJ-70099731 in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [18F]-JNJ-70099731
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Camrelizumab in Combination With Apatinib and Temozolomide as First-line Treatment in Advanced Acral Melanoma
Status: RECRUITING
Conditions: Acral Melanoma
Interventions: DRUG: camrelizumab+apatinib+TMZ|DRUG: camrelizumab+apatinib|DRUG: camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ethibond Suture vs Vessel Loop as Draining Seton for Complex Anal Fistulas
Status: RECRUITING
Conditions: Anal Fistula
Interventions: PROCEDURE: Ethibond suture|PROCEDURE: Vessel loop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Absolute Quantification of Coronary Flow Reserve by Stress Perfusion MRI
Status: COMPLETED
Conditions: Myocardial Ischemia
Interventions: DRUG: Regadenoson|DRUG: gadofoveset trisodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Curcumin on Inflammation and Oxidative Stress in Pediatric Patients on Regular Hemodialysis: A Randomized, Double-Blind, Placebo-Controlled Pilot Study
Status: RECRUITING
Conditions: Pediatric Patients Having Renal Failure and on Regular Hemodialysis
Interventions: DIETARY_SUPPLEMENT: Curcumin capsules 1 gm|DIETARY_SUPPLEMENT: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Suprachoroidal Triamcinolone Acetonide in Harada's Retinal Detachment
Status: COMPLETED
Conditions: Vogt Koyanagi Harada Disease
Interventions: DRUG: Suprachoroidal Triamcinolone acetonide injection for serous retinal detachment in VKH disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peanut Sublingual Immunotherapy (SLIT)-Tablet for Treatment of Peanut Allergy
Status: RECRUITING
Conditions: Peanut Allergy
Interventions: BIOLOGICAL: Peanut SLIT-tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Performance of 3T MRI T2 Mapping Technique in Chondro-labral Pathology of the Hip, Correlated With Intraoperative Arthroscopic Findings: Interventional Diagnostic Technique Validation Study (HPI MRI 3T)
Status: WITHDRAWN
Conditions: Hip Injuries and Disorders|Hip Arthrosis
Interventions: DIAGNOSTIC_TEST: T2 mapping 3T MRI + hip arthroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lower Limb Arthroplasty: Effects of a Tele Prehabilitation Program With Indirect Electrostimulation.
Status: NOT_YET_RECRUITING
Conditions: Osteo Arthritis Knee and Hip|Lower Limb Arthroplasty
Interventions: DEVICE: ELECTROSTIMULATION (ES)|OTHER: EXERCISE (C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT