pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intradermal Influenza Vaccination
Status: RECRUITING
Conditions: Vaccine Reaction
Interventions: DEVICE: MicronJet|BIOLOGICAL: Fluzone® Quadrivalent|BIOLOGICAL: Fluzone® Quadrivalent|OTHER: Bacteriostatic Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac Disease
Status: RECRUITING
Conditions: Coronary Artery Disease|Myocarditis|Infiltrative Cardiomyopathy|Dilated Cardiomyopathy|Hypertrophic Cardiomyopathy|Aortic Valve Stenosis|Aortic Valve Regurgitation|Pericardial Effusion|Congenital Heart Disease|Vascular Anomaly
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Non-Invasive, Real-Time Technology for Diagnosis of Cervical Tissue
Status: TERMINATED
Conditions: Cervix|Cancer
Interventions: PROCEDURE: Colposcopy, Spectroscopy, and Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single-center Study of Gustation in Idiopathic Parkinson's Disease and Lewy Body Disease Using Gustatory Evoked Potential Analysis
Status: RECRUITING
Conditions: Idiopathic Parkinson's Disease and Lewy Body Disease
Interventions: BIOLOGICAL: Fasting blood test|OTHER: Subject interview|OTHER: Motor assessment|OTHER: Neurocognitive assessment|OTHER: Nutritional assessment|OTHER: Taste tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: 3 Part Study to Assess Inhaled Nitric Oxide on Functional Pulmonary Imaging in Subj. Pulmonary Hypertension Associated w/ COPD and IPF
Status: COMPLETED
Conditions: Pulmonary Hypertension|Chronic Obstructive Pulmonary Disease|Idiopathic Pulmonary Fibrosis
Interventions: DRUG: inhaled Nitric Oxide - 30 mcg/kg IBW/hr|DRUG: inhaled Nitric Oxide 5,10,15 mcg/Kg IBW/hr|DRUG: inhaled nitric oxide 75 mcg/kg IBW/hr
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hereditary Sensory Neuropathy Serine Trial
Status: RECRUITING
Conditions: Hereditary Sensory Neuropathy Type I
Interventions: DRUG: L-serine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nintedanib and Capecitabine in Treating Patients With Refractory Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colon Adenocarcinoma|Rectal Adenocarcinoma|Recurrent Colon Carcinoma|Recurrent Rectal Carcinoma|Stage IVA Colon Cancer|Stage IVA Rectal Cancer|Stage IVB Colon Cancer|Stage IVB Rectal Cancer
Interventions: DRUG: Capecitabine|OTHER: Laboratory Biomarker Analysis|DRUG: Nintedanib|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Gladskin on Disease Severity and the Skin Microbiome, Including Staphylococcus Aureus, in Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DEVICE: Staphefekt SA.100|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First In Human Safety, Pharmacokinetics and Anti-tumoral Activity of GM102 in Gynecological Cancers
Status: COMPLETED
Conditions: Neoplasm, Gynecologic
Interventions: DRUG: GM102|DRUG: GM102 escalating doses|DRUG: GM102
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Palpatory and Preprocedural Ultrasound Guided Techniques on Performance of Spinal Anesthesia
Status: COMPLETED
Conditions: Pregnancy
Interventions: PROCEDURE: Ultrasound|DEVICE: The spinal needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iontophoresis Delivery of Dexamethasone Phosphate for Non-infectious, Non-necrotizing Anterior Scleritis, Phase 1 Dose-varying Study
Status: COMPLETED
Conditions: Non-infectious, Non-necrotizing Anterior Scleritis
Interventions: DRUG: Dexamethasone Phosphate Ophthalmic Solution (EGP-437)|DRUG: Dexamethasone phosphate ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: One vs. Three Hyperbaric Oxygen Treatments for Acute Carbon Monoxide Poisoning
Status: COMPLETED
Conditions: Carbon Monoxide Poisoning
Interventions: COMBINATION_PRODUCT: Hyperbaric Oxygen (HBO2) - 3 sessions|COMBINATION_PRODUCT: Hyperbaric Oxygen (HBO2) - 1 session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect GnRH Agonist Administration in Endometriosis Cyst Patients
Status: RECRUITING
Conditions: Endometriosis
Interventions: DRUG: Triptorelin Embonate|DRUG: Triptorelin Embonate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrated RF and B-mode Deformation Analysis for 4D Stress Echocardiography
Status: WITHDRAWN
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Stress Dobutamine Echocardiographic using 4DE System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MRSA in a Trauma Population: Does Decolonization Prevent Infection?
Status: COMPLETED
Conditions: MRSA Colonization
Interventions: DRUG: Chlorhexidine, Mupirocin|DRUG: Soap baths, Lubricating Jelly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study of NS-065/NCNP-01 in Boys With Duchenne Muscular Dystrophy (DMD)
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: NS-065/NCNP-01
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telaprevir in HIV-HCV Coinfected Patients Who Had Previously Failed a Peginterferon-Ribavirin Regimen
Status: COMPLETED
Conditions: Hepatitis C, Chronic|HIV Infection
Interventions: DRUG: Telaprevir|BIOLOGICAL: pegIFN alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of the Composition of Temporary Restorative Material in Vital Teeth
Status: UNKNOWN
Conditions: MTA|Dental Restoration, Temporary
Interventions: PROCEDURE: Carie removal|PROCEDURE: Relative isolation|PROCEDURE: Manipulation of the temporary material based on Zinc Oxide and Eugenol|PROCEDURE: Manipulation of the temporary material based on Mineral trioxide aggregate|PROCEDURE: Material insertion on the cavity|PROCEDURE: Finishing the temporary direct restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Temsirolimus in Treating Patients With Recurrent or Persistent Endometrial Cancer
Status: COMPLETED
Conditions: Recurrent Endometrial Carcinoma
Interventions: BIOLOGICAL: bevacizumab|DRUG: temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of CTM for Tennis ELbow
Status: ENROLLING_BY_INVITATION
Conditions: Tennis Elbow|Lateral Epicondylitis \(Tennis Elbow\)|Lateral Elbow Tendinopathy
Interventions: DEVICE: CTM|DRUG: Celestone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Remifentanil on Attenuating the Hemodynamic Responses After Electroconvulsive Therapy
Status: UNKNOWN
Conditions: Haemodynamic Rebound
Interventions: DRUG: Sevoflurane|DRUG: Remifentanil|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extraction and Socket Preservation Before Implant Placement Using Freezed Dried Allograft (FDBA) and Platelet-Rich Fibrin in Smokers
Status: COMPLETED
Conditions: A-PRF
Interventions: BIOLOGICAL: platelet rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Culturally Tailored Educational Video to Promote Lung Cancer Screening in Vulnerable Communities
Status: RECRUITING
Conditions: Cigarette Smoking-Related Carcinoma|Lung Carcinoma
Interventions: PROCEDURE: Discussion|OTHER: Media Intervention|OTHER: Interview|OTHER: Media Intervention|OTHER: Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: An Open-Label, Single-Dose, Mass-Balance Study to Assess the Disposition of 14C-Labeled PRT054021 in Healthy Male Subjects
Status: COMPLETED
Conditions: Health Volunteers
Interventions: DRUG: Betrixaban single oral dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Addition of Opaganib to Androgen Antagonists in Patients With mCRPC
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Opaganib|DRUG: Abiraterone|DRUG: Enzalutamide|DRUG: Opaganib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Partner Services Pre-exposure Prophylaxis (PS-PrEP)
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Transmission, Transtheoretical Model of Change
Interventions: BEHAVIORAL: PS-PrEP Intervention Group|BEHAVIORAL: PrEPLine Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study on B7-H3 Targeted Affibody Radioligand Probes for PET Imaging of Solid Tumors
Status: RECRUITING
Conditions: B7H3|CD276 Affibody|PET/CT Imaing
Interventions: DRUG: [68Ga] B7H3 Affibody-BCH
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single Dose and 34-Day Tolerance Study of INGAP Peptide in Insulin Deficient Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: INGAP Peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ultrasound Guided Laser Ablation Therapy on Symptomatic Benign Thyroid Nodules
Status: COMPLETED
Conditions: Thyroid Nodule
Interventions: DEVICE: Laser ablation of benign thyroid nodule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Group Focused Psychosocial Support for Adults Affected by Humanitarian Crises
Status: COMPLETED
Conditions: Depression|Posttraumatic Stress Disorder|Psychological Distress
Interventions: BEHAVIORAL: Group problem management plus|BEHAVIORAL: Enhanced treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of PATANASE Nasal Spray in Patients With Perennial Allergic Rhinitis
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: Olopatadine hydrochloride 0.6% nasal spray (PATANASE)|OTHER: Olopatadine nasal spray vehicle, pH 3.7|OTHER: Olopatadine nasal spray vehicle, pH 7.0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Impact of INSTI to PI Switch on Insulin Sensitivity and Fat Metabolism
Status: COMPLETED
Conditions: HIV I Infection|Adiposity
Interventions: PROCEDURE: Frequently sampled glucose tolerance testing|PROCEDURE: abdominal subcutaneous adipose tissue biopsy|PROCEDURE: MRI scan to assess intrahepatic triglyceride content
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: GrafixPRIME® for the Treatment of Chronic Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Foot Ulcer, Diabetic
Interventions: OTHER: GrafixPRIME®|PROCEDURE: Dressing Application|DEVICE: Off-loading (walking boot)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Medicurtain® in Patients With Hysteroscopy (Pivotal Study)
Status: COMPLETED
Conditions: Intrauterine Synechiae|Tissue Adhesion, Surgery-Induced
Interventions: DEVICE: Medicurtain®|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Opioid Rotation Versus Opioid Escalation in Patients With Moderate to Severe Cancer Pain
Status: UNKNOWN
Conditions: Cancer|Pain
Interventions: DRUG: oral oxycodone|DRUG: oral hydromorphone|DRUG: fentanyl patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gefitinib in Treating Patients Who Are Undergoing Surgery and/or Radiation Therapy for Locally Advanced or Recurrent Squamous Cell Skin Cancer
Status: COMPLETED
Conditions: Recurrent Skin Cancer|Squamous Cell Carcinoma of the Skin
Interventions: DRUG: Gefitinib|RADIATION: Radiotherapy|PROCEDURE: Conventional surgery|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CARAT: Canagliflozin vs. Placebo for Post Bariatric Patients With Persistent Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2|Obesity
Interventions: DRUG: canagliflozin|DRUG: Placebo (for canagliflozin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adverse Effects of Red Blood Cell Transfusions: A Unifying Hypothesis (Aim 3)
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: BIOLOGICAL: Storage-aged red blood cells (saRBCs) units|BIOLOGICAL: Fresh red blood cells units
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of TH-302 in Combination With Gemcitabine Compared With Gemcitabine Alone in Previously Untreated Patients With Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Gemzar (Gemcitabine)|DRUG: TH-302|DRUG: TH-302
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LeucoPatch® in Nonhealing Wounds With Exposed Bone or Tendon Study
Status: WITHDRAWN
Conditions: Wound Healing Delayed
Interventions: DEVICE: LeucoPatch®|OTHER: Control,
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nab-paclitaxel as Second-line Therapy in Locally Advanced or Metastatic Squamous Lung Cancer
Status: UNKNOWN
Conditions: Squamous Cell Carcinoma of Lung
Interventions: DRUG: nanoparticle albumin-bound paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Imaging Techniques That Predict Antidepressant Responsiveness
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Venlafaxine ERT|DRUG: Fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cognitive Support Technology for Postsecondary Students With Traumatic Brain Injuries
Status: UNKNOWN
Conditions: TBI (Traumatic Brain Injury)
Interventions: BEHAVIORAL: : Cognitive Support Technology (CST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Effectivenes of IASTM and MET on Post Operative Elbow Stiffness
Status: COMPLETED
Conditions: Elbow Stiffness
Interventions: OTHER: IASTM|OTHER: METS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT): A Feasibility Clinical Trial
Status: COMPLETED
Conditions: Ventilator Associated Pneumonia (VAP)|Other Infections|Antibiotic-Associated Diarrhea|C-Difficile|Duration of Mechanical Ventilation|Length of ICU Stay|Length of Hospital Stay|ICU and Hospital Mortality
Interventions: DRUG: L. rhamnosus GG - Probiotic|OTHER: Placebo - Microcrystalline Cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cerebral Oxygen Saturation Measurement During Cardioversion Because of Atrial Fibrillation
Status: COMPLETED
Conditions: Electrical Cardioversion of Atrial Fibrillation|Pharmacological Cardioversion of Atrial Fibrillation
Interventions: DEVICE: SenSmart Model X-100, Nonin Medical
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Acute Long-acting Bronchodilation on Oxygenation and Peripheral Ventilation in COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: LABA|DRUG: LAMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Neuromuscular Electrical Stimulation Combined With Blood Flow Restriction on Muscular and Cardiovascular Function
Status: UNKNOWN
Conditions: Muscle Weakness|Muscle Atrophy
Interventions: DEVICE: Neuromuscular electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Postoperative Radiation, Cisplatin, and Panitumumab in Locally Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Cancer of Head|Cancer of Head and Neck|Cancer of Neck|Cancer of the Head|Cancer of the Head and Neck|Cancer of the Neck|Head and Neck Cancer|Head Cancer|Head Neoplasms|Head, Neck Neoplasms|Neck Cancer|Neck Neoplasms|Neoplasms, Head|Neoplasms, Head and Neck|Neoplasms, Neck|Neoplasms, Upper Aerodigestive Tract|UADT Neoplasms|Upper Aerodigestive Tract Neoplasms
Interventions: DRUG: Panitumumab|DRUG: Cisplatin|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acute Arterial Hypertension on Morphine's Requirements and Postsurgical Pain.
Status: COMPLETED
Conditions: Hypertensive Disease|Pain, Postoperative
Interventions: OTHER: SBP 20-30% over baseline|OTHER: SBP 20-30% under baseline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Efficacy of Heparin-boned Viabahn Endoprosthesis and Paclitaxel-coated Balloons for Complex Femoropopliteal Lesions
Status: NOT_YET_RECRUITING
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Viabahn endoprosthesis group|DEVICE: Drug-coated balloon group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Ion Releasing Hybrid Restorative Material
Status: UNKNOWN
Conditions: Dental Caries
Interventions: OTHER: Conventional resin composite|OTHER: Activa Presto|OTHER: Giomer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Investigate the Systemic Exposure, Safety, and Local Tolerability of SJP002 Ophthalmic Solution in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SJP002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of SGN-30 (Antibody) in Patients With Refractory or Recurrent Anaplastic Large Cell Lymphoma
Status: COMPLETED
Conditions: Anaplastic Large-Cell Lymphoma
Interventions: DRUG: SGN-30 (anti-CD30 mAb)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Proactive Community Case Management to Reduce Child Mortality
Status: COMPLETED
Conditions: Under-five Child Mortality|Access to Health Care
Interventions: OTHER: Proactive Community Case Management|OTHER: Integrated Community Case Management|OTHER: Removal of point-of-care user fees|OTHER: Infrastructure improvements at primary health centre|OTHER: Training of primary health centre staff
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Fasting Study of Ciprofloxacin Extended-Release Tablets 500 mg and Cipro® XR Tablets 500 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ciprofloxacin Extended-Release Tablets 500 mg|DRUG: Cipro® XR Tablets (500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Rituximab and Dexamethasone in Treating Patients With Low-Grade Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Contiguous Stage II Grade 1 Follicular Lymphoma|Contiguous Stage II Grade 2 Follicular Lymphoma|Contiguous Stage II Marginal Zone Lymphoma|Cutaneous B-cell Non-Hodgkin Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Nodal Marginal Zone B-cell Lymphoma|Noncontiguous Stage II Grade 1 Follicular Lymphoma|Noncontiguous Stage II Grade 2 Follicular Lymphoma|Noncontiguous Stage II Marginal Zone Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Marginal Zone Lymphoma|Splenic Marginal Zone Lymphoma|Stage I Grade 1 Follicular Lymphoma|Stage I Grade 2 Follicular Lymphoma|Stage I Marginal Zone Lymphoma|Stage III Grade 1 Follicular Lymphoma|Stage III Grade 2 Follicular Lymphoma|Stage III Marginal Zone Lymphoma|Stage IV Grade 1 Follicular Lymphoma|Stage IV Grade 2 Follicular Lymphoma|Stage IV Marginal Zone Lymphoma|Waldenstrom Macroglobulinemia
Interventions: OTHER: pharmacological study|BIOLOGICAL: rituximab|DRUG: dexamethasone|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Upper Gastrointestinal Disease on the Pharmacokinetics of Oral Semaglutide in Subjects With Type 2 Diabetes.
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Domperidone to Increase Milk Production in Mothers With Newborns in Neonatology
Status: COMPLETED
Conditions: Breastfeeding
Interventions: DRUG: Domperidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Acute Mood Depressive Episode in Borderline Personality Disorder With rTMS
Status: RECRUITING
Conditions: Depressive Disorder, Major|Borderline Personality Disorder
Interventions: DEVICE: Left Dorsolateral Prefrontal Cortex (L-DLPFC)|DEVICE: Dorsomedial Prefrontal Cortex (DMPFC)|DEVICE: Sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Amniotic Membranes in Complex Genitourinary Reconstruction
Status: WITHDRAWN
Conditions: Hypospadias|Hypospadias and Epispadias and Other Penile Anomalies|Fistula|Fistula, Urinary|Bladder Exstrophy and Epispadias Complex|Bladder and Bladder Neck Disorders (Excluding Calculi)
Interventions: BIOLOGICAL: Amniotic membranes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Subcutaneous Secukinumab for Moderate to Severe Chronic Plaque-type Psoriasis for up to 1 Year
Status: COMPLETED
Conditions: Moderate to Severe Plaque-type Psoriasis
Interventions: DRUG: secukinumab 150 mg|DRUG: placebo to secukinumab 150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rivaroxaban Post-Transradial Access for the Prevention of Radial Artery Occlusion
Status: RECRUITING
Conditions: Radial Artery Occlusion
Interventions: DRUG: Rivaroxaban 15 MG Oral Tablet [Xarelto]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improving Pediatric COVID-19 Vaccine Uptake Using an mHealth Tool
Status: COMPLETED
Conditions: COVID-19 Vaccines|Telemedicine|Vaccine Hesitancy|Pediatric ALL
Interventions: BEHAVIORAL: COVID-19 Vaccine Uptake App|OTHER: General Health App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Maintenance Therapy After Platinum-containing Chemotherapy in Patients With Recurrent Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Fluzoparib Capsules|DRUG: Apatinib Mesylate Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Raxibacumab on Immunogenicity of Anthrax Vaccine Adsorbed
Status: COMPLETED
Conditions: Infections, Bacterial
Interventions: BIOLOGICAL: AVA|BIOLOGICAL: Raxibacumab|DRUG: Diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Decolonization and Surgical Site Infections - a Prospective Randomized Trial
Status: COMPLETED
Conditions: Orthopedic Disorders|Surgical Site Infection
Interventions: DRUG: Mupirocin 2% nasal ointement|DRUG: Chlorhexidine sol 4%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CX-01 Combined With Azacitidine in the Treatment of Relapsed or Refractory Myelodysplastic Syndrome and Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Myelodysplastic Syndromes|Acute Myeloid Leukemia|AML|MDS
Interventions: DRUG: CX-01|DRUG: Azacitidine|PROCEDURE: Bone marrow biopsy|PROCEDURE: Peripheral blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Resistance In Eye Surgeries
Status: UNKNOWN
Conditions: Antibiotic Resistance|Ocular Surface Microbiome|Gut Resistome
Interventions: DRUG: Moxifloxacin (Topical)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IV Iron-induced Hypophosphatemia After RYGB
Status: RECRUITING
Conditions: Hypophosphatemia|Roux-en-Y Gastric Bypass
Interventions: DRUG: Iron isomaltoside|DRUG: Iron Carboxymaltose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Lung Function Imaging Study of Pulmonary Fibrosis Combined With Emphysema Syndrome
Status: RECRUITING
Conditions: Using Functional Lung MRI to Explore Pulmonary Perfusion Changes in Patients With Pulmonary Fibrosis and Emphysema Syndrome
Interventions: DEVICE: MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Ocular Changes by Surgical Menopause Using Optical Coherence Tomography (OCT)
Status: COMPLETED
Conditions: Corneal Deformity|Macular Degeneration Advanced|Surgical Menopause
Interventions: DIAGNOSTIC_TEST: Optic coherence tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of TAK-954 to Treat Gastrointestinal Dysfunction in Adults After Surgery
Status: COMPLETED
Conditions: Postoperative Gastrointestinal Dysfunction
Interventions: DRUG: TAK-954 Placebo|DRUG: TAK-954
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Open Label Trial To Evaluate Pain Relief With Intravenous Followed By Oral Therapy With Parecoxib/Valdecoxib 40 Mg/Day For Treatment Of Post-Laparoscopic Surgery Pain
Status: TERMINATED
Conditions: Pain, Post Surgical
Interventions: DRUG: parecoxib/valdecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Healthy Volunteers of the Reversion by Haemostatic Drugs of the Anticoagulant Effect of New Anti-thrombotics
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Rivaroxaban, Dabigatran|DRUG: Dabigatran; Rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Myositis Interstitial Lung Disease Nintedanib Trial
Status: RECRUITING
Conditions: Myositis Associated Interstitial Lund Disease (MA-ILD)
Interventions: DRUG: Nintedanib|DRUG: Placebo|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Block Versus Local Anesthetic Infiltration for Pain Control in the Abdominal Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: transversus abdominis plane block|PROCEDURE: local infiltration|PROCEDURE: Patient controlled analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Homeopathy for Moderate Depression (Acute Phase)
Status: TERMINATED
Conditions: Major Depression
Interventions: DRUG: homeopathic q-potencies|DRUG: Placebo|OTHER: homeopathic case history taking type I|OTHER: homeopathic case history type II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient-Centered Communication of Life Expectancy Estimates in Genitourinary Malignancies
Status: UNKNOWN
Conditions: Prostate Cancer Stage I|Kidney Cancer Stage I|Bladder Cancer Stage II|Prostate Cancer Stage II
Interventions: BEHAVIORAL: Patient-centered communication of life expectancy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Infrared Laser Moxibustion on Cancer-related Fatigue in Breast Cancer Patients
Status: COMPLETED
Conditions: Cancer-related Fatigue
Interventions: DEVICE: Infrared Laser Moxibustion|DEVICE: Sham Infrared Laser Moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ⅱ Study of Neoadjuvant Chemotherapy Followed by Concurrent Chemoradiation for Stage Ⅲ Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: docetaxel, cisplatin, fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetes Self-Management Plus Tai Chi Easy
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: Diabetes Self-Management Education and Support (DSMES) plus Tai Chi Easy (TCE)™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Etanercept and Celecoxib to Treat Temporomandibular Disorders (Painful Joint Conditions)
Status: COMPLETED
Conditions: Temporomandibular Joint Disorder
Interventions: DRUG: Etanercept|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of Copanlisib and Ibrutinib in Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Mantle Cell Lymphoma (MCL)
Interventions: DRUG: Copanlisib|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IV Dexmedetomidine in the Duration of Spinal Anesthesia With Hyperbaric Bupivacaine: Double Blind Randomized Trial.
Status: UNKNOWN
Conditions: Anesthesia|Dexmedetomidine
Interventions: DRUG: Dexmedetomidine injection|DRUG: Sodium Chloride 0.9% infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transfusional Trigger in Post-operative Oncologic Patients in Critical Care
Status: UNKNOWN
Conditions: Transfusion|Oncology|Critical Care|Surgery
Interventions: PROCEDURE: Restrictive transfusional strategy|PROCEDURE: Liberal transfusional strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial to Evaluate the Safety, Reactogenicity, and Immunogenicity of MVA-BN Yellow Fever Vaccine With and Without Montanide ISA-720 Adjuvant in 18-45 Year Old Healthy Volunteers
Status: COMPLETED
Conditions: Yellow Fever|Yellow Fever Immunisation
Interventions: DRUG: ISA-720|BIOLOGICAL: MVA Smallpox Vaccine|BIOLOGICAL: MVA-BN Yellow Fever Vaccine|OTHER: Placebo|OTHER: Placebo|BIOLOGICAL: YF Vax 17D Strain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Periodontal Disease and P. Gingivalis in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Osteoarthritis|Periodontal Disease
Interventions: RADIATION: Digital xray of jaw and teeth|PROCEDURE: Blood draw|OTHER: questionnaires|PROCEDURE: Periodontal Examination|OTHER: Bilateral digital xray of hands
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hypoglycemia Associated Autonomic Failure in Type 1 Diabetes Mellitus (DM)
Status: RECRUITING
Conditions: Type 1 Diabetes|Hypoglycemia Associated Autonomic Failure
Interventions: DRUG: Fluoxetine|DRUG: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study on Efficacy and Safety of Acoziborole (SCYX-7158) in Patients Infected by Human African Trypanosomiasis Due to T.b. Gambiense
Status: COMPLETED
Conditions: Trypanosomiasis, African|Gambiense Trypanosomiasis|Sleeping Sickness
Interventions: DRUG: Acoziborole (SCYX-7158)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resistive Action Video Games Enhance Functional Fitness of Disabled Workers in Sheltered Workshops
Status: COMPLETED
Conditions: Mental Disorder
Interventions: BEHAVIORAL: Training program incorporating video aerobic exercise, action video game and resistive action video game
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: RAD001 and AV-951 in Patients With Refractory, Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Gastrointestinal Cancer
Interventions: DRUG: Everolimus|DRUG: Tivozanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CMV Specific T Cell Therapy After Allogeneic Stem Cell Transplantation.
Status: COMPLETED
Conditions: Hematological Malignancies|CMV Infection
Interventions: GENETIC: CMV-specific T cells|DRUG: Standard anti-viral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptive Optics for Ophthalmic Technologies
Status: TERMINATED
Conditions: Diabetic Retinopathy|Diabetic Macular Edema
Interventions: DEVICE: WF-AO-OCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Ombitasvir/ABT-450/Ritonavir and Dasabuvir Therapy With Low Dose Ribavirin (RBV), Full Dose RBV or RBV Add-On in Treatment Naive Genotype 1a Hepatitis C Virus Infected Adults
Status: COMPLETED
Conditions: Chronic Hepatitis C|Hepatitis C (HCV)|Hepatitis C Genotype 1a
Interventions: DRUG: Ombitasvir/ABT-450/Ritonavir|DRUG: Dasabuvir|DRUG: Ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Fludarabine in Pediatric Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Acute Leukemia|Chronic Leukemia|Severe Aplastic Anemia
Interventions: DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Plantar Sensory Training in Individuals With Hallux Valgus.
Status: COMPLETED
Conditions: Hallux Valgus|Pain|Balance; Distorted
Interventions: OTHER: Plantar Sensorial Training|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety and Efficacy of Naftifine Hydrochloride Gel 2% and Naftin® Gel 2% in Tinea Pedis
Status: COMPLETED
Conditions: Tinea Pedis
Interventions: DRUG: Naftifine Hydrochloride Gel 2%|DRUG: Naftin® Gel 2%|DRUG: Placebo Topical Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy of Water & Indigo Carmine vs. Water or Air Method on Adenoma Detection Rate (ADR) - a Randomized Controlled Trial (RCT)
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: Indigo carmine|PROCEDURE: water (exchange) method|PROCEDURE: water (exchange) plus dye method|PROCEDURE: air method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 25OH Vitamin D Overdoses and Risk of Bronchopulmonary Dysplasia or Death
Status: RECRUITING
Conditions: Bronchopulmonary Dysplasia|Vitamin D Overdose
Interventions: BIOLOGICAL: Is 25 OH vitamin D overdose a risk factor of bronchopulmonary dysplasia or death ?
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intraoperative Mitomycin C in Lacrimal Sac Mucocele
Status: COMPLETED
Conditions: Lacrimal Mucocele
Interventions: PROCEDURE: Canaliculo- Dacryocystorhinostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the EHPAD Caregiver/Pact & Pad Psycho-educational Program for Caregivers With an Institutionalized Parent
Status: RECRUITING
Conditions: Caregivers
Interventions: BEHAVIORAL: Psycho-educational program EHPAD caregivers / Pact & Pad for caregivers with a parent in an institution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: VR Usage in Non-Invasive Surgical Sub-Specialty Procedures
Status: COMPLETED
Conditions: Stress, Emotional|Stress, Psychological|Behavioral Symptoms
Interventions: BEHAVIORAL: Technology Based Distractions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Azenosertib in Uterine Serous Carcinoma: Biomarker Study
Status: NOT_YET_RECRUITING
Conditions: Uterine Serous Carcinoma|Uterine Carcinoma|Uterine Cancer
Interventions: DRUG: Azenosertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Local Anesthesia Versus Continuous Femoral Nerve Bloc After Total Knee Arthroplasty: Impact on Mean Discharge Aptitude Delay
Status: TERMINATED
Conditions: Total Knee Arthroplasty
Interventions: DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Haemostasis After Venous Access in Atrial Fibrillation Catheter Ablation: The HARNESS Trial
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Femoral Vein Injury|Bleeding
Interventions: OTHER: A figure-of-eight suture secured with a three-way tap|OTHER: Shortened bed rest duration of 2-hours|OTHER: Manual compression|OTHER: Conventional bed rest duration of 4-hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With Chronic Hepatitis C and Chronic Renal Failure.
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: peginterferon alfa-2a [Pegasys]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corifollitropin Alfa Compared to Daily rFSH in Poor Responders Undergoing ICSI
Status: COMPLETED
Conditions: Subfertility
Interventions: DRUG: Corifollitropin alfa|DRUG: rFSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ascorbic Acid, Corticosteroids, and Thiamine in Sepsis (ACTS) Trial
Status: COMPLETED
Conditions: Sepsis|Septic Shock|Metabolic Disturbance
Interventions: DRUG: vitamin C, vitamin B1, hydrocortisone|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Flu Vaccine Against Childhood Pneumonia, Bangladesh
Status: COMPLETED
Conditions: Pneumonia|Laboratory Confirmed Influenza
Interventions: BIOLOGICAL: Trivalent inactivated influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Real World Treatment Study of AZD9291 for Advanced/Metastatic EGFR T790M Mutation NSCLC
Status: COMPLETED
Conditions: Lung Cancer
Interventions: PROCEDURE: T790M+ Testing|PROCEDURE: Baseline Visit Blood & Urine Testing|PROCEDURE: Baseline ECG|PROCEDURE: Visual Slit-Lamp Testing|DRUG: AZD9291 Dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxazosin Effects on ABPM in Hypertensive Patients With Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetes Mellitus|Essential Hypertension|Renal Failure
Interventions: DRUG: Effects of doxazosin on morning surge in diabetic patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Susceptibility Test -Driven Sequential Therapy as the Third Line Therapy for Refractory Helicobacter Pylori Infection
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: susceptibility test guided sequential therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Precise Transplantation of hAESCs Into the Ventricle for Parkinson's Disease.
Status: NOT_YET_RECRUITING
Conditions: Parkinson's Disease
Interventions: BIOLOGICAL: hAESCs treatment|BIOLOGICAL: placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physiologic Accelerated Pacing as a Treatment in Patients With Heart Failure With Preserved Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure, Diastolic
Interventions: DEVICE: Dual chamber pacemaker|OTHER: Accelerated Physiologic Pacing|OTHER: Nocturnal Pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER