pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Relative Bioavailability of a Single Dose of Nintedanib Given Alone and in Combination With Multiple Doses of Rifampicin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nintedanib|DRUG: Rifampicin|DRUG: Nintedanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Bioavailability of Different Formulations of AZD5718 and the Food Effect on the Selected Formulation of AZD5718 in Healthy Volunteers
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Form 1 of AZD5718 tablets|DRUG: Form 2 of AZD5718 tablets|DRUG: Form 3 of AZD5718 tablets|DRUG: Form 4 of AZD5718 tablets|DRUG: Form 5 of AZD5718 tablets|DRUG: Selected form (Form 2 - 5) of AZD5718 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Tolerance and Pharmacokinetics of TQB2618 Injection in Subjects With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Solid Tumors
Interventions: DRUG: TQB2618 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Point-Of-Care Creatinine Assays in Patients With eGFR <30 Receiving Intravascular Contrast
Status: WITHDRAWN
Conditions: Renal Insufficiency|Acute Kidney Injury|Contrast-induced Nephropathy
Interventions: DIAGNOSTIC_TEST: serum creatinine assay
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy Of Elonide Nasal Corticosteroids In Managing Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Elonide Nasal Spray|DRUG: Nasonex Nasal Spray|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Zanthoxylum Nitidum Tincture for Paronychia Caused by Afatinib
Status: UNKNOWN
Conditions: Paronychia
Interventions: DRUG: zanthoxylum nitidum tincture|DRUG: tetracycline ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Multi-center Study on Total Hip Arthroplasty With E1
Status: TERMINATED
Conditions: Hip Osteoarthritis
Interventions: DEVICE: Femoral Stem|DEVICE: Acetabular Cup|DEVICE: Acetabular Liner
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Solid Tumors With Intratumoral Hiltonol® (Poly-ICLC)
Status: TERMINATED
Conditions: Melanoma|Squamous Cell Carcinoma of the Head and Neck|Squamous Cell Carcinoma of the Skin|Sarcoma of the Skin|Basal Cell Cancer of the Skin|Breast Cancer
Interventions: DRUG: Poly-ICLC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Anti-leukemic Activity of Vodobatinib (K0706) for Treatment of Ph+ CML Resistant/Intolerant to ≥3 Prior CML Therapies
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy (For Part A)|Chronic Myeloid Leukemia (for Part B and C)
Interventions: DRUG: Vodobatinib (K0706) capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of a Virtually Supervised Exercise Intervention and Group Counseling on Inflammation and the Microbiome of Smokers at High Risk for Lung Cancer, BE FIT Trial
Status: RECRUITING
Conditions: Lung Carcinoma
Interventions: OTHER: Best Practice|PROCEDURE: Biospecimen Collection|OTHER: Exercise Counseling|OTHER: Exercise Intervention|OTHER: Medical Device Usage and Evaluation|OTHER: Physical Performance Testing|OTHER: Questionnaire Administration|OTHER: Telemedicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Functional Electrical Stimulations With and Without Motor Priming Exercises in Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: OTHER: Functional electrical stimulations and motor priming exercise|OTHER: Functional electrical stimulations|OTHER: Conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RM-493 Treatment Trial in Proopiomelanocortin (POMC) Deficient Patients
Status: UNKNOWN
Conditions: Homozygous or Compound Heterozygous POMC, LEPR or PCSK1 Gene Mutation
Interventions: DRUG: RM-493
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceleration of Recovery From General Anesthesia - Efficacy of Isocapnic Hyperpnoea in Obese Patients Undergoing Isoflurane Anesthesia
Status: COMPLETED
Conditions: Recovery Time From Isoflurane Anesthesia in Obese Patients
Interventions: OTHER: Isocapnic Hyperpnoea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sacituzumab Govitecan and Intrathecal Chemotherapy for Treating Leptomeningeal Metastases From Her2-negative Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Leptomeningeal Metastases
Interventions: DRUG: Sacituzumab Govitecan|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pirfenidone in Adult Hospitalized Patients With COVID-19
Status: COMPLETED
Conditions: COVID-19 Pneumonia
Interventions: DRUG: Pirfenidone Oral Product|DRUG: Pirfenidone placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Sleep With a Digital Cognitive Behavioral Therapy for Insomnia Application
Status: NOT_YET_RECRUITING
Conditions: Insomnia
Interventions: DEVICE: Web-based Cognitive Behavioral Therapy for Insomnia (wCBT-I
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Umbilical Cord Mesenchymal Stem Cells For the Treatment of Lumbar Disc Degeneration Disease
Status: UNKNOWN
Conditions: Lumbar Disc Degeneration|Lumbar Disc Herniation
Interventions: OTHER: human umbilical cord mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dosimetry, Safety and Potential Benefit of 177Lu-PSMA-617 Prior to Prostatectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms
Interventions: DRUG: 177Lu-PSMA-617
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Calcipotriol Cream and (Calcipotriol + Betamethasone Dipropionate) Ointment in Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Calcipotriol, (calcipotriol + betamethasone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Cathodal tDCS in ADHD
Status: COMPLETED
Conditions: ADHD
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of N-methyl-D-aspartate (NMDA) Enhancers for Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: sarcosine|DRUG: sarcosine+ BE|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Subcutaneous Administration of TEV-48125 for the Preventive Treatment of Episodic Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: TEV-48125|DRUG: TEV-48125 or placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of CinnoRA (Adalimumab-CinnaGen) And Adalimumab (Humira) In Healthy Subjects
Status: COMPLETED
Conditions: Bioequivalence|Phase 1
Interventions: DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sentinel Lymph Node Mapping in Esophageal Cancer Using ICG Dye and NIR Imaging
Status: RECRUITING
Conditions: Esophageal Cancer
Interventions: OTHER: Injection of indocyanine green (ICG)dye|DEVICE: Near-Infrared Image-Guided|PROCEDURE: Sentinel Lymph Node (SLN) mapping
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety Study of Vandetanib (ZD 6474) in Combination With Bicalutamide Versus Bicalutamide Alone in Patients With Chemotherapy Naive Hormone Refractory Prostate Cancer.
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Vandetanib|DRUG: Bicalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vitamin D Supplementation on Glucose Metabolism in Non-Diabetic African American Adults
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: vitamin D3, cholecalciferol|DIETARY_SUPPLEMENT: Inactive comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Fibromyalgia and Olive Oil
Status: UNKNOWN
Conditions: Fibromyalgia
Interventions: DIETARY_SUPPLEMENT: Extra Virgin Olive Oil|DIETARY_SUPPLEMENT: Refined Olive Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sensitivity of Pharmacokinetics to Differences in Aerodynamic Particle Size Distribution
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone Propionate Formulation 1|DRUG: Fluticasone Propionate Formulation 2|DRUG: Fluticasone Propionate Formulation 3|DRUG: Fluticasone Propionate Formulation 3*
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Adjuvant Xeloda Plus Eloxatin +/- Avastin After Radical Resection of Liver Metastasis of Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer|Liver Metastases
Interventions: DRUG: oxaliplatin+capecitabine|DRUG: Oxaliplatin+capecitabine+bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Philips Intracardiac Echocardiography (ICE) Clinical Registry
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation|Stroke|Valve Disease, Heart|Atrial Septal Defect|Patent Foramen Ovale|Mitral Valve Disease|Tricuspid Valve Disease|Aortic Valve Disease
Interventions: DEVICE: ICE Image guidance
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mother Screening for Relapse Using Mid-upper Arm Circumference Among Children Recovered From Severe Acute Malnutrition
Status: RECRUITING
Conditions: Severe Acute Malnutrition
Interventions: OTHER: Mother education on how to perform MUAC assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Use of Large-dose, Extended Interval Vancomycin Intravenous Administration for Skin and Soft Tissue Infections
Status: COMPLETED
Conditions: Skin and Soft Tissue Infections
Interventions: DRUG: vancomycin|DRUG: vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Nitrate Supplementation on Elite Runners
Status: COMPLETED
Conditions: Nutrition|Physical Performance|Sport Physiology|Nitrates|Elite Athletes
Interventions: DIETARY_SUPPLEMENT: nitrate-rich beetroot juice|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Impact of Oral Versatile Antioxidants on Glaucoma Progression
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Gingko Biloba|DRUG: α-tocopherol|DRUG: Placebo|DRUG: Antioxidant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 1b Study With Volociximab in Combination With Carboplatin, Paclitaxel, and Bevacizumab in First-line, Advanced Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: M200 (Volociximab), Carboplatin, Paclitaxel, Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Randomized Trial of the Reduction of Chemotherapy in Philadelphia Chromosome-positive ALL of Young Adults
Status: RECRUITING
Conditions: Philadelphia Chromosome Positive Adult Acute Lymphoblastic Leukemia
Interventions: DRUG: Nilotinib|DRUG: Methotrexate|DRUG: Aracytine (Ara C)|DRUG: Granulocyte Colony-Stimulating Factor (G-CSF)|DRUG: Depomedrol|DRUG: Dexamethasone|DRUG: Vincristine|DRUG: Imatinib|DRUG: 6 Mercaptopurine (6MP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Doxycycline and Cefuroxime Axetil for Treatment of Erythema Migrans: Clinical and Microbiological Outcome
Status: COMPLETED
Conditions: Erythema Migrans|Post-Lyme Disease Symptoms
Interventions: DRUG: doxycycline|DRUG: cefuroxime axetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Comparison of Tiotropium Daily + Salmeterol Daily or Twice Daily Versus Tiotropium Daily in Patients With COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium (Tio18GEL)|DRUG: Salmeterol MDPI (Salm50DPI)|DRUG: Tiotropium (T18GEL) + Salmeterol MDPI (S_DPI)|DRUG: Tiotropium/Salmeterol (T+S_PE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Study of Two Dosing Schedules of Adalimumab in Subjects With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: adalimumab|DRUG: placebo for adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: School Activity for the Reduction of Distress, Pain and Negative Emotions in Children Experiencing Hospital School
Status: COMPLETED
Conditions: Hospital School Experience
Interventions: OTHER: Hospital School Experience, point of view of the children|OTHER: Hospital School Experience, point of view of the hospital teachers|OTHER: Hospital School Experience, point of view of the non hospital teachers|OTHER: Hospital School Experience, point of view of parents
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Novel Regimens in Relapsed or Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: EOS884448|DRUG: Iberdomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Experience of Chronic (Non-malignant) Musculoskeletal Pain of French Adolescent and Young Adult: a Qualitative Research With Their Physicians and Non-medical Practitioners
Status: COMPLETED
Conditions: Chronic (Non-malignant) Musculoskeletal Pain
Interventions: OTHER: semi-structured interviews
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigating the Safety and Efficacy of the Treatment With the Non-compliant Jade Balloon in TASC C and D Athero-occlusive Infra-inguinal Disease in Patients With Chronic Limb Threatening Limb Ischemia From SingaporE
Status: UNKNOWN
Conditions: Critical Limb Ischemia|Peripheral Artery Disease
Interventions: DEVICE: JADE Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Using Dilute Vinegar to Find Changes in Cells During Endoscopy for Patients With Barrett's Oesophagus" (The ABBA Study)
Status: COMPLETED
Conditions: Barrett Esophagus
Interventions: DRUG: Acetic Acid|PROCEDURE: Non targeted quadrantic biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study of Metformin in Head and Neck Squamous Cell Cancer and Its Effects on Stromal-epithelial Metabolic Uncoupling
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Cancer
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Self-Sampling in Women Who Do Not Undergo Routine Cervical Screening
Status: COMPLETED
Conditions: Health Status Unknown|Precancerous Condition
Interventions: BEHAVIORAL: compliance monitoring|OTHER: cervical Papanicolaou test|OTHER: educational intervention|OTHER: screening questionnaire administration|OTHER: survey administration|PROCEDURE: colposcopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness and Safety of Autologous ADRC for Treatment of Anterior Cruciate Ligament Partial Rupture
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Partial Rupture
Interventions: PROCEDURE: Liposuction|DEVICE: ADRC isolation|PROCEDURE: Arthroscopic surgery|OTHER: Intraarticular administration of autologous ADRC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capsaicin for the Treatment of Cannabinoid Hyperemesis Syndrome
Status: UNKNOWN
Conditions: Cannabinoid Hyperemesis Syndrome
Interventions: DRUG: Capsaicin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of a Self-contained Direct Digital Radiography System for Breast Specimen Imaging
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DEVICE: Trident Specimen Radiography System|DEVICE: Bioptics, Faxitron, and Full Field Digital Mammography (FFDM) Selenia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comprehensive HHT Outcomes Registry of the United States (CHORUS)
Status: RECRUITING
Conditions: Hereditary Hemorrhagic Telangiectasia|Arteriovenous Malformations|Telangiectasia|Epistaxis|GastroIntestinal Bleeding|Cerebral Arteriovenous Malformations|Vascular Malformation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Burnout Preventions, Professionalism Heightening, and Enhancing Resiliency (BUPHER)
Status: UNKNOWN
Conditions: Professional-Patient Relations|Burnout, Professional
Interventions: OTHER: Preventing Professionals burnout
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: tDCS for the Management of Chronic Visceral Pain in Patients With Chronic Pancreatitis
Status: WITHDRAWN
Conditions: Chronic Pancreatitis|Pain
Interventions: DEVICE: tDCS|BEHAVIORAL: Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inferior Vena Cava Collapsibility and Distensibility Assessment in Critical Care.
Status: RECRUITING
Conditions: Sepsis|Acute Renal Failure|Acute Gastroenteritis|Diabetic Ketoacidosis
Interventions: DIAGNOSTIC_TEST: Inferior Vena Cava Collapsibility/distensibility Index (IVC CI/DI) assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study To Examine Toxicity Of Allogeneic Stem Cell Transplantation For Relapsed Or Therapy Refractory Ewings Sarcoma
Status: COMPLETED
Conditions: EWINGS SARCOMA
Interventions: DRUG: Rabbit anti-thymocyte globulin|DRUG: Busulfan|DRUG: Melphalan|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regenecare® Wound Gel in Treating Rash in Patients Receiving Cetuximab or Other Epidermal Growth Factor Receptor Inhibitor Therapy for Cancer
Status: UNKNOWN
Conditions: Dermatologic Complications|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DIETARY_SUPPLEMENT: collagen/aloe vera/vitamin E/lidocaine topical hydrogel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Brexpiprazole in Alcohol Use Disorder
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: Brexpiprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mobilising Tumour and Immune Cells Via Exercise in Chronic Lymphocytic Leukaemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Minimal Residual Disease
Interventions: OTHER: Exercise trial
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diabetes Prevention Program
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent|Glucose Intolerance
Interventions: BEHAVIORAL: Intensive lifestyle|DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effectivity of the Mobile App "HARKIT I-Care" in Secondary Prevention in Post-ACS Patients
Status: RECRUITING
Conditions: Acute Coronary Syndrome
Interventions: DEVICE: HARKIT I-Care Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Ultrasound Guided Superficial Cervical Plexus Block for Tracheal Reconstruction Surgery:
Status: COMPLETED
Conditions: Efficiency of Using Ultrasound-guided SCB for Providing Intra and Postoperative Analgesiatracheal Reconstruction Surgery
Interventions: PROCEDURE: superficial cervical plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Helicobacter Rescue Therapy With Berberine Plus Amoxicillin Quadruple Therapy Versus Tetracycline Plus Furazolidone Quadruple Therapy
Status: COMPLETED
Conditions: Gastric Ulcer|Chronic Gastritis|Gastric Cancer|Helicobacter Pylori Infection|Gastritis
Interventions: DRUG: Berberine|DRUG: Amoxicillin|DRUG: Esomeprazole|DRUG: Bismuth|DRUG: Tetracycline|DRUG: Furazolidone|DRUG: Esomeprazole|DRUG: Bismuth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing 6-Minute Walk Tests for Ambulatory Oxygen Assessment
Status: RECRUITING
Conditions: Respiratory Disease
Interventions: DIAGNOSTIC_TEST: Maximal 6-minute Walk Test (Max_6MWT)|DIAGNOSTIC_TEST: Normal speed 6-minute Walk Test (Nor_6MWT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Oral Zinc Therapy for the Prevention of Mucositis
Status: COMPLETED
Conditions: Mucositis
Interventions: DRUG: Zinc|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: GRAPE • Glycemic Response of Amylopectin Containing Drinks
Status: TERMINATED
Conditions: Glycemic Index
Interventions: DIETARY_SUPPLEMENT: Carbohydrate drink|DIETARY_SUPPLEMENT: Energy smart Carbohydrate blend|DIETARY_SUPPLEMENT: Liquid Dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Effects of Cervical Vasopressin Versus no Premedication on Blood Loss During Vaginal Hysterectomy: A Randomized, Placebo Controlled Trial
Status: COMPLETED
Conditions: Blood Loss During Vaginal Hysterectomy
Interventions: DRUG: Vasopressin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Synergy of Elevation of the Head and Thorax and REBOA During Out-of-Hospital Cardiac Arrest
Status: NOT_YET_RECRUITING
Conditions: Heart Arrest|Cardiac Arrest, Out-Of-Hospital|Cardiopulmonary Arrest|Cardiopulmonary Resuscitation
Interventions: PROCEDURE: REBOA|DEVICE: Head-Up Cardiopulmonary Resuscitation (AHUP-CPR)|DEVICE: Mechanical Chest Compression Device with Active Chest Decompression|DEVICE: Impedance Threshold Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Selective COX-II Inhibitor as an Adjuvant Therapy in Patients With Resectable Advanced Stomach Cancer ( Histological Staging ≥ T2N1) - A Multi-Centre Prospective Randomised Controlled Trial
Status: UNKNOWN
Conditions: Cancer of Stomach
Interventions: DRUG: Oral Vioxx (Rofecoxib)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of DER 45-EV Gel to Treat Rosacea
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: DER 45 EV|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PMCF Study on EDOF (Isopure) vs Monofocal (Micropure) IOL
Status: ACTIVE_NOT_RECRUITING
Conditions: Cataract|Lens Opacities
Interventions: DEVICE: IOL implantation experimental (Isopure 1.2.3.)|DEVICE: IOL implantation active comparator (Micropure 1.2.3.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis And Inadequate Response Or Intolerance to a First Anti-TNF Alpha Therapy
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Rituximab|DRUG: Adalimumab|DRUG: Etanercept|DRUG: Infliximab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Trial for Large ER-Negative Breast Cancers
Status: COMPLETED
Conditions: Malignant Neoplasm of Female Breast
Interventions: DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: Docetaxel|DRUG: Capecitabine|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Ambrisentan for Liver Function Test Rescue in Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: ambrisentan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Medical Benefit of Spa Therapy on Fibrosis After Postoperative Radiotherapy for Breast Cancer
Status: RECRUITING
Conditions: Fibrosis|Breast Cancer
Interventions: OTHER: Thermal cure with a primary dermatological indication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Teledi@Log - Tele-rehabilitation of Heart Patients
Status: COMPLETED
Conditions: Heart Failure|Myocardial Infarction|Angina Pectoris|Coronary Stenosis|Mitral Valve Stenosis
Interventions: DEVICE: Telerehabilitation programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Different Bupivacaine Volumes in Infiltration Between Popliteal Artery and Capsule of Knee Block
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Bupivacaine 0.25% Preservative-Free Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study With Self-administered Rocatinlimab in Adolescent and Adult Participants With Moderate-to-severe AD
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: COMBINATION_PRODUCT: Rocatinlimab Prefilled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of Eszopiclone in Patients With Insomnia (Study SEP 190-150)
Status: COMPLETED
Conditions: Insomnia
Interventions: DRUG: Eszopiclone 1 mg- Elderly|DRUG: Eszopiclone 2 mg- Elderly|DRUG: Eszopiclone 3 mg- Non-elderly|DRUG: Eszopiclone 2 mg- Non-elderly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Humeral Head Depressor Muscle Co-Activation Training in Terms of Functional Outcomes
Status: COMPLETED
Conditions: Rotator Cuff Tears|Surgery
Interventions: OTHER: Humeral Head Depressor Muscle Co-Activation Training- Experimental Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Fat Mediated Modulation of Reproductive and Endocrine Function in Young Athletes
Status: COMPLETED
Conditions: Exercise-related Amenorrhea
Interventions: DRUG: Transdermal 17Beta-estradiol, progesterone|DRUG: Ethinyl Estradiol + Desogestrel|DIETARY_SUPPLEMENT: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab Plus Olaparib Administered Prior to Surgery of Resectable Urothelial Bladder Cancer (NEODURVARIB)
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: Durvalumab|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy and Ocular Surface Assessment Between BRIDIN-plus and Combigan in Glaucoma or Ocular Hypertensive
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertensive
Interventions: DRUG: BRIDIN-plus Eye drops|DRUG: Combigan Eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Lidocaine Volume on Discomfort During Administration of Local Anesthetic
Status: COMPLETED
Conditions: Needlestick Injuries
Interventions: PROCEDURE: 2 ml 1% Lidocaine|PROCEDURE: 1 ml 2% Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improving the Appearance of Skin and Hair in Patients Undergoing Valley Fever Treatment
Status: TERMINATED
Conditions: Valley Fever|Coccidioidomycosis
Interventions: OTHER: Cholesterol-containing moisturizers
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Implantable Electronic Device Implantation With and Without Pectoral Nerve Block
Status: UNKNOWN
Conditions: Cardiac IED Implantation
Interventions: PROCEDURE: Pectoral Nerve Block|PROCEDURE: Without Pectoral Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: OTHER
Clinical trial: Rate Control in Atrial Fibrillation II
Status: COMPLETED
Conditions: Atrial Fibrillation|Permanent Atrial Fibrillation
Interventions: DRUG: Metoprolol|DRUG: Diltiazem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Prevention and Treatment of Atherosclerotic Cerebral Occlusive Disease With Remote Ischemic Conditioning
Status: UNKNOWN
Conditions: Cerebral Atherosclerosis
Interventions: COMBINATION_PRODUCT: Doctormate®+Medical Management|DRUG: Medical Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: VELCADE in MALT Lymphoma Pretreated With More Than One Prior Systemic Therapy
Status: TERMINATED
Conditions: Lymphoma, Mucosa-Associated Lymphoid Tissue
Interventions: DRUG: Bortezomib (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy of Dotinurad and Febuxostat for the Treatment of Participants With Gout
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: Dotinurad|DRUG: Febuxostat|OTHER: Dotinurad Matched Placebo|OTHER: Febuxostat Matched Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mobile Health Fitness Program for Adolescent and Young Adult Childhood Cancer Survivors
Status: COMPLETED
Conditions: Survivorship|Fatigue
Interventions: BEHAVIORAL: Exercise Intervention|BEHAVIORAL: Internet-Based Intervention|DEVICE: Monitoring Device|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Efficacy and Safety of Colchicine Combined With Conventional Therapy in Multiple Myeloma Patients
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Colchicine|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-blind Randomized Clinical Trial on the Efficacy of Magnetic Sacral Roots Stimulation for the Treatment of NE
Status: COMPLETED
Conditions: Nocturnal Enuresis
Interventions: DEVICE: rSMS in treatment of Nocturnal Enuresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Aminobutyric Acid, Glutamic Acid, Calcium, Thiamine, Pyridoxine and Cyanocobalamin as Therapy for Vertigo
Status: COMPLETED
Conditions: Vertigo
Interventions: DRUG: Gamma-aminobutyric acid tartarate, glutamic acid, dibasic calcium phosphate, thiamine nitrate, pyridoxine chloride and cyanocobalamin|DRUG: Ginger
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preemptive Local Anesthesia in Vaginal Surgery
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: bupivacaine and epinephrine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Diagnostics of Bacterial Infections and Antibiotic Resistance in Blood Samples and Rectal Swabs Using Real Time PCR-ARES PCR Methods
Status: RECRUITING
Conditions: Drug Resistant Bacterial Infection
Interventions: DIAGNOSTIC_TEST: ARES PCR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Control-IQ Technology 2.0 in Adults, Children, and Preschoolers With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: t:slim X2 insulin pump with Control-IQ technology 2.0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy and Safety With CD19CAR-T for Relapsed or Refractory Non-Hodgkin Lymphoma
Status: UNKNOWN
Conditions: Relapsed Non-Hodgkin Lymphoma|Refractory Non-Hodgkin Lymphoma
Interventions: COMBINATION_PRODUCT: CD19 CART
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety and Efficacy of the Coadministration of Ibrexafungerp With Voriconazole in Patients With Invasive Pulmonary Aspergillosis
Status: TERMINATED
Conditions: Invasive Pulmonary Aspergillosis
Interventions: DRUG: SCY-078|DRUG: Voriconazole|OTHER: Oral Placebo Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 3D Planned Surgery of Acute Fractures Performed With 3D Guides Printed at the Point of Care
Status: RECRUITING
Conditions: Fracture Tibia|Fracture Femur|Fracture, Comminuted
Interventions: DEVICE: Fracture reposition with 3D printed patient specific repositions guides
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-FAPI and 18F-FDG PET/CT in Patients With Various Types of Cancer
Status: UNKNOWN
Conditions: Cancer
Interventions: DIAGNOSTIC_TEST: 18F-FAPI PET/CT and 18F-FDG PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Feasibility, and Efficacy of TSCS on Stabilizing Blood Pressure for Acute Inpatients With SCI
Status: RECRUITING
Conditions: Acute Spinal Cord Injury|Spinal Cord Injuries|Neuromodulation|Traumatic Spinal Cord Injury|Spinal Cord Stimulation|SCI - Spinal Cord Injury|Blood Pressure|Blood Pressure Disorders
Interventions: DEVICE: Digitimer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GVD±R Regimen for ASCT-eligible Patients With Refractory/Relapsed DLBCL
Status: UNKNOWN
Conditions: Lymphoma, Large B-Cell, Diffuse
Interventions: DRUG: gemcitabine, vinorelbine and doxorubicin liposome, with or without rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Association Between Loneliness and Substance Use
Status: COMPLETED
Conditions: Opioid Use|Loneliness
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for loneliness (CBT-L)|BEHAVIORAL: Physical Health Education Training (PHET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of APD-791 With Aspirin and/or Clopidogrel
Status: TERMINATED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Clopidogrel|DRUG: Aspirin|DRUG: APD791|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Probiotic Use in Patients With Prior COPD Exacerbation
Status: WITHDRAWN
Conditions: COPD|Obstructive Lung Disease
Interventions: DIETARY_SUPPLEMENT: Lactobacillus GG|OTHER: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Daclizumab Versus Thymoglobulin in Renal Transplant Recipients With High Immunological Risk
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: DRUG: Thymoglobulin (ATG)|DRUG: Daclizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Food on Pharmacokinetics and Pharmacodynamics of Asasantin ER in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Asasantin ER|OTHER: Standardized breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Status With Early Childhood Caries
Status: COMPLETED
Conditions: Early Childhood Caries, Vitamin D Deficiency
Interventions: DIAGNOSTIC_TEST: serum vitamin D , calcium , parathyroid hormone and albumin level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Guided Thoracic Paravertebral Block for Percutaneous Nephrolithotomy Operations in Children
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: paravertebral blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Dapagliflozin Taken Twice-daily
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: dapagliflozin|DRUG: dapagliflozin|DRUG: dapagliflozin|DRUG: metformin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Immunotherapy With Durvalumab (MEDI4736) in Non-Surgical Early Stage or Locally Advanced Non-Small Cell Lung Cancer (NSCLC) Followed by Radical Radiotherapy or Chemoradiotherapy
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Durvalumab|OTHER: standard of care RT/RCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Denosumab in Subjects With Giant Cell Tumor of Bone
Status: COMPLETED
Conditions: Cancer|Giant Cell Tumors|Giant Cell Tumor of Bone|Benign Giant Cell Tumors
Interventions: DRUG: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-center Study of Spherule-Derived Coccidioidin
Status: COMPLETED
Conditions: Coccidioidomycosis
Interventions: BIOLOGICAL: Spherule-derived coccidioidin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Infliximab (Remicade) on Fat Free Mass in Patients With Moderate to Severe COPD Suffering From Cachexia
Status: COMPLETED
Conditions: COPD|Cachexia
Interventions: DRUG: infliximab (Remicade)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Contractility Modulation in Patients With Chronic Heart Failure and the Various Forms of Atrial Fibrillation
Status: COMPLETED
Conditions: Heart Failure|Atrial Fibrillation|Left Ventricular Ejection Fraction
Interventions: DEVICE: optimizer smart
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bariatric-metabolic Surgery - the Effect of Postoperative Exercising on Sarcopenia
Status: NOT_YET_RECRUITING
Conditions: Sarcopenia|Obesity|Sarcopenic Obesity
Interventions: PROCEDURE: Laparoscopic sleeve gastrectomy|OTHER: Strength endurance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7058584 Following 7 Days of Instillation of Eye Drops in Patients With Primary Open Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma, Open-angle|Ocular Hypertension
Interventions: DRUG: 0.01% RO7058584|DRUG: 0.1% RO7058584|DRUG: 1% RO7058584|DRUG: Matching Placebo|DRUG: Latanoprost 0.005%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Methylprednisolone Before Fludeoxyglucose-Labeled Positron Emission Tomography in Patients With Lung Cancer
Status: WITHDRAWN
Conditions: Lung Cancer
Interventions: DRUG: methylprednisolone|RADIATION: fludeoxyglucose F 18|PROCEDURE: positron emission tomography|PROCEDURE: computed tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dose Timing of D-Cycloserine to Augment CBT for Social Anxiety Disorder
Status: COMPLETED
Conditions: Social Anxiety Disorder
Interventions: DRUG: D-Cycloserine|DRUG: Placebo|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT