pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Amifostine to Treat Side Effects of Treatment in Patients Receiving Radiation Therapy and Cisplatin for Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Drug/Agent Toxicity by Tissue/Organ|Head and Neck Cancer|Oral Complications|Radiation Toxicity
Interventions: DRUG: amifostine trihydrate|DRUG: cisplatin|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Migration and Head Penetration of Vitamin-E Diffused Cemented Polyethylene Cup in Total Hip Arthroplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Total Hip Arthroplasty
Interventions: DEVICE: Vitamin-E diffused polyethylene acetabular component|DEVICE: Standard polyethylene acetabular component
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer
Status: SUSPENDED
Conditions: Glioblastoma|Gliosarcoma|MGMT-Unmethylated Glioblastoma|Recurrent Glioblastoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Magnetic Resonance Imaging|DRUG: Navtemadlin|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Drug-drug Interactions (DDIs) of IBI362 With Metformin, Warfarin, Atorvastatin, Digoxin in Overweight or Obese Subjects
Status: COMPLETED
Conditions: Overweight Subjects|Obese Subjects
Interventions: DRUG: metformin|DRUG: digoxin|DRUG: IBI362|DRUG: warfarin|DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Subcostal Transversus Abdominis Plane Versus Paravertebral Block in the Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Cholecystitis
Interventions: PROCEDURE: USG guided Subcostal TAP block|PROCEDURE: USG guided Paravertebral Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Periapical Bone Healing After Apicectomy With and Without Retrograde Root Filling
Status: UNKNOWN
Conditions: Stomatognathic Disease|Mouth Disease|Periapical Disease|Alveolar Bone Loss
Interventions: PROCEDURE: Mineral Trioxide Aggregate (MTA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aromatherapy Using a Nasal Clip After Surgery
Status: UNKNOWN
Conditions: Post-operative Nausea
Interventions: OTHER: Aromatherapy blend|OTHER: Duration of effectiveness of the essential oil blend|OTHER: Participant comfort using the nasal clip delivery system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Expectation, Medication and Placebo on Objective and Self-rated Performance
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Substance Use Disorder
Interventions: DRUG: Methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of IPACK Block and PCI for Postoperative Analgesia and Function Recovery Following Total Knee Arthroplasty
Status: COMPLETED
Conditions: Total Knee ArthroplastyKnee Pain, Functionality
Interventions: DRUG: PCI (0.25% marcaine+ 2.0 μg/mL of adrenaline + %0.9 saline)|DRUG: IPACK(0.25% marcaine+ 2.0 μg/mL of adrenaline + %0.9 saline)|DRUG: ACB ( 0.25% marcaine + %0.9 saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Trial to Evaluate the Efficacy and Safety of COL-1620 Vaginal Progesterone Gel
Status: COMPLETED
Conditions: Luteal Hormone Supplementation in In-vitro Fertilization|Embryo Transfer
Interventions: DRUG: COL-1620|DRUG: Gonadotropin-releasing hormone (GnRH) analogue|DRUG: Follicle-stimulating hormone (FSH)|DRUG: Human Chorionic Gonadotropin (hCG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ferinject® Assessment in Patients With Iron Deficiency and Chronic Heart Failure (FAIR-HF)
Status: COMPLETED
Conditions: Chronic Heart Failure|Iron Deficiency|Iron Deficiency Anemia|Anaemia
Interventions: DRUG: Ferinject ® (Ferric carboxymaltose)|DRUG: Normal saline (0.9%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravesical Electromotive Mitomycin After Bacillus Calmette-Guérin Failure
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: COMBINATION_PRODUCT: intravesical electromotive administration of mitomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual Channel Rehabilitation Technology Promotes Rapid Recovery of Upper Limbs After Stroke
Status: UNKNOWN
Conditions: Stroke|Upper Extremity Dysfunction|Transcranial Direct Current Stimulation|Image, Body
Interventions: BEHAVIORAL: Transcranial Direct Current Stimulation therapy|BEHAVIORAL: Motor imagery therapy|BEHAVIORAL: Transcranial Direct Current Stimulation and motor imagery therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy and Safety of Insulin Glargine/Lixisenatide Fixed Ratio Combination to Insulin Glargine in Patients With Type 2 Diabetes Insufficiently Controlled on Basal Insulin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin glargine/Lixisenatide (HOE901/AVE0010)|DRUG: Insulin glargine (HOE901)|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Realization of Sequencing of All Known Human Genes in Case of Detection of Cerebral, Renal or Ophthalmological Fetal Malformations During Pregnancy in Order to Make an Etiological Diagnosis and to Precise the Fetal Prognosis
Status: UNKNOWN
Conditions: Fetal Malformation|Pregnancy Related|Rare Genetic Disease
Interventions: GENETIC: CGH-array and exome sequencing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of AR-67 (Formerly DB-67) in Adult Patients With Refractory or Metastatic Solid Malignancies
Status: COMPLETED
Conditions: Tumors
Interventions: DRUG: AR-67 (formerly DB-67)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rotational Stability of the Acrysof, Tecnis and Envista Intraocular Lenses
Status: COMPLETED
Conditions: Cataract|Astigmatism
Interventions: OTHER: Implantation of an Alcon Acrysof SN60WF intraocular lens|OTHER: Implantation of an AMO Tecnis ZCB00 intraocular lens|OTHER: Implantation of an Envista MX60 intraocular lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Combination of Tacrolimus and High-dose Dexamethasone as First-line Treatment in Adult Immune Thrombocytopenia
Status: UNKNOWN
Conditions: ITP|Immune Thrombocytopenia
Interventions: DRUG: Dexamethasone|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects and Central Mechanism of Electroacupuncture and MRI-navigated rTMS for PSD
Status: RECRUITING
Conditions: Post-stroke Depression|Healthy
Interventions: DEVICE: electro-acupuncture|DEVICE: MRI-navigated rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Extension Study Administering YM155 to Subjects Previously Enrolled in Another Protocol Administering YM155
Status: COMPLETED
Conditions: Prostate Cancer|Melanoma|Non-Hodgkin's Lymphoma
Interventions: DRUG: YM155
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Upper Limb Muscular Strengthening in the Rehabilitation of Patients Submitted to the Breast Cancer Surgical Treatment
Status: COMPLETED
Conditions: Muscle Strength Quantitative Trait Locus 1
Interventions: PROCEDURE: Physiotherapy Guidance|PROCEDURE: Physiotherapy Muscle strengthening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Evaluation of Topical Treatments for Moderate-Severe Facial Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: BLI1100-1|DRUG: BLI1100-2|DRUG: BLI1100-3|DRUG: BLI1100-4|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utility of 3D Navigation to Reduce Ionizing Radiation in Common Flutter Ablation. Study of Personnel and Patient Dosimetry
Status: UNKNOWN
Conditions: Auricular Flutter|Radiation Exposure
Interventions: PROCEDURE: conventional X-ray based Fluoroscopy|PROCEDURE: low X-ray 3D navigation technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of Multimodal Ablation Remodeling Immunosensitized PD-1 in the Treatment of Pancreatic Cancer With Liver Metastasis
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: DEVICE: Multi-mode thermal ablation device|DRUG: Intravenous anti-PD-1 and chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sparsity-based Magnetic Resonance Imaging of Cardiac Arrhythmias
Status: SUSPENDED
Conditions: Cardiac Arrythmias
Interventions: OTHER: 3D Imaging|OTHER: Late Gadolinium Enhancement (LGE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate Drug-drug Interactions Between BR1017-1 and BR1017-2 in Healthy Volunteers
Status: COMPLETED
Conditions: Hypertension|Hypercholesterinemia
Interventions: DRUG: BR1017-1|DRUG: BR1017-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health Behavior Feedback Study for Veterans With Hepatitis C
Status: COMPLETED
Conditions: Alcoholism|Alcohol Abuse|Hepatitis C|Liver Disease
Interventions: BEHAVIORAL: 3 session brief intervention with health behavior feedback|OTHER: treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Feasibility of Focal Therapy for Prostate Cancer of Good Prognosis With Permanent I125 Localized Implant.
Status: COMPLETED
Conditions: Localized Prostate Cancer
Interventions: RADIATION: Focal brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Antiretroviral (Triumeq) in Patients With Amyotrophic Lateral Sclerosis (ALS).
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Triumeq
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hip Osteoarthritis and Foot Orthoses Trial (HOOT)
Status: RECRUITING
Conditions: Hip Osteoarthritis
Interventions: DEVICE: Foot orthoses|DEVICE: Flat shoe insert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Neo-adjuvant Weekly Paclitaxel With or Without Carboplatin in Early Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: carboplatin+ paclitaxel|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of PRX004 in Subjects With Amyloid Transthyretin (ATTR) Amyloidosis
Status: TERMINATED
Conditions: Amyloidogenic Transthyretin (ATTR) Amyloidosis
Interventions: DRUG: PRX004
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Complement Factor H Polymorphism in the Regulation of Choroidal Vascular Tone in Young Healthy Subjects
Status: UNKNOWN
Conditions: Age-Related Macular Degeneration
Interventions: GENETIC: the polymerase chain reaction (PCR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Removal Of CytoKines With cytoSorbenTs After Inflammatory Response Reaction During Cardiac Surgery
Status: RECRUITING
Conditions: Inflammatory Response
Interventions: DEVICE: cytokine adsorber (CytoSorb®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clevidipine vs Placebo or Standard of Care for Dyspnea and Blood Pressure Control in AHF
Status: WITHDRAWN
Conditions: Dyspnea|Hypertension|Acute Heart Failure
Interventions: DRUG: Stage 1: Clevidipine (double-blinded)|DRUG: Stage 1: Placebo (double-blinded)|DRUG: Stage 2: Clevidipine (open-label)|DRUG: Stage 2: Standard of Care (open-label)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CIK Cell Transfusion Plus Gefitinib As Second Or Third-Line Treatment for Advanced Adenocarcinoma Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Group A:cytokine-induced killer cell +gefitinib|DRUG: Group B:Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise and Mindfulness in Patients With Non-specific Chronic Low Back Pain: The BACKFIT Project
Status: ACTIVE_NOT_RECRUITING
Conditions: Low Back Pain
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Exercise + mindfulness|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Terbinafine and Itraconazole
Status: NOT_YET_RECRUITING
Conditions: Tinea Corporis|Tinea Cruris|Tinea Faciei|Dermatophytoses
Interventions: DRUG: Terbinafine Tablets|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Popliteal Block for Lower Limb Angioplasty
Status: COMPLETED
Conditions: Angioplasty|Anaesthesia and Analgesia
Interventions: PROCEDURE: Popliteal block|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Trial of Pulse Steroid Therapy in Kawasaki Disease--Pediatric Heart Network
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Infection|Coronary Aneurysm
Interventions: DRUG: Steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Treadmill and Whole Body Vibration Training in Children With Attention Deficit Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: OTHER: Treadmill training|OTHER: Whole body vibration training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STereotActic Body Radiotherapy and 177Lutetium PSMA in Locally Advanced Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Malignant Neoplasm of Prostate|Locally Advanced Prostate Cancer
Interventions: DRUG: Lu-PSMA-617|RADIATION: 5-fraction Stereotactic Body Radiation Therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transoral Endoscopic Thyroidectomy by Vestibular Approach (TOETVA)
Status: RECRUITING
Conditions: Thyroid Diseases|Thyroid Cancer
Interventions: PROCEDURE: TOETVA|PROCEDURE: conventional thyroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 1% Acetic Acid vs Normal Saline Dressing inManagement of Diabetic Foot
Status: ACTIVE_NOT_RECRUITING
Conditions: Granulation of Chronic Diabetic Wounds|Diabetic Wounds
Interventions: BIOLOGICAL: 1% Acetic acid dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Using the Subglottic Pressure to Predict the Dysphagia After Partial Laryngectomy
Status: RECRUITING
Conditions: Laryngeal Cancer|Dysphagia
Interventions: PROCEDURE: Open partial horizontal laryngectomy(OPHL), Type I-III|PROCEDURE: Transoral endoscopic laser cordectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vitamin D to Resolve Inflammation After Tuberculosis (ResolveD-TB)
Status: COMPLETED
Conditions: Recurrent Tuberculosis
Interventions: DIETARY_SUPPLEMENT: Fultium-D3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Porcine Acellular Dermal Matrix for the Treatment of Localized Gingival Recessions
Status: RECRUITING
Conditions: Gingival Recession
Interventions: DEVICE: Porcine acellular dermal matrix|OTHER: Coronally advanced flap (CAF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Characterizing the Pharmacokinetic Profile of a Novel Encapsulated Caffeine Beverage and Associated Mood and Physiological Effects
Status: COMPLETED
Conditions: Alertness
Interventions: OTHER: Flavored caffeinated beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: High-dose Brachytherapy Boost With Stereostatic Body Radiation Therapy to Intermediate or Higher Risk Prostate Cancer
Status: RECRUITING
Conditions: Prostatic Cancer
Interventions: RADIATION: High Dose Brachytherapy|RADIATION: Stereostatic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The ENHANCE Study: Exercise and Nutrition in Head And Neck CancEr Survivors
Status: RECRUITING
Conditions: Oral Cavity Cancer|Oropharynx Cancer|Hypopharynx Cancer|Larynx Cancer
Interventions: BEHAVIORAL: ENHANCE Intervention - Exercise and Nutrition|BEHAVIORAL: ENHANCE Intervention - Nutrition Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pilot Study Assessing the Feasibility and Effectiveness of a Breastfeeding Educational Video on Breastfeeding Rates
Status: COMPLETED
Conditions: Breastfeeding, Exclusive
Interventions: BEHAVIORAL: Breastfeeding Video Education|BEHAVIORAL: Breastfeeding PDF education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of EA on Depression Related Insomnia: Study Protocol for a Multicenter RCT
Status: UNKNOWN
Conditions: Insomnia Due to Mental Disorder
Interventions: DEVICE: Electroacupuncture(EA)|DEVICE: Placebo acupuncture|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Biocellulose Wound Dressing Containing Silk Sericin and PHMB for STSG Donor Sites
Status: UNKNOWN
Conditions: Wound|Disorder of Skin Donor Site
Interventions: DEVICE: The novel biocellulose wound dressing|DEVICE: Bactigras
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ONO-4538 Phase II Rollover Study (ONO-4538-98)
Status: RECRUITING
Conditions: Pan-tumor
Interventions: DRUG: ONO-4538|DRUG: oxaliplatin|DRUG: S-1|DRUG: capecitabine|DRUG: bevacizumab|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Results Of Patient Rated Asthma Control Test In Comparison To Diary Card Data
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Salmeterol/Fluticasone 50/250 mcg|DRUG: Salbutamol 100 mcg|DEVICE: DISKUS™ powder inhalers
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Repetitive Transcranial Magnetic Stimulation for Auditory Verbal Hallucinations
Status: TERMINATED
Conditions: Schizophrenia and Related Disorders
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Way to Be Active IV (Framing vs Incentives)
Status: COMPLETED
Conditions: Sedentary Lifestyle
Interventions: BEHAVIORAL: Financial incentives|BEHAVIORAL: Teams|BEHAVIORAL: Framing of feedback|BEHAVIORAL: Daily Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Insulin Detemir Given Once or Twice Daily in Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin detemir|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Survival and Success Rates of External- and Internal- Connection Dental Implants Placed Within the United Kingdom Armed Forces.
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Implant Failed|Tooth Loss|Implant Complication
Interventions: PROCEDURE: Platform-switched implant placement|PROCEDURE: Platform-matched implant placement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Near-Infrared Perfusion During Minimally Invasive Thoracic Surgery Download
Status: UNKNOWN
Conditions: Lung Neoplasms|Esophageal Lesion
Interventions: DEVICE: Olympus VE2 NIR Imaging System|DRUG: Indocyanine green
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Effect of ACP-196 on the Heart Rate-corrected QT Interval in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ACP-196|DRUG: Moxifloxacin 400 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prosthetic Motility and Complications in Pegged Versus Unpegged Hydroxyapatite Orbital Implants
Status: UNKNOWN
Conditions: Anophthalmos|Orbital Implants
Interventions: PROCEDURE: orbital implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chlorhexidine Vaginal Preparation for Reduction of Post-cesarean Endometritis and Sepsis
Status: COMPLETED
Conditions: Postpartum Endometritis|Wound Infection|Chlorhexidine Adverse Reaction|Postoperative Fever
Interventions: DRUG: Chlorhexidine Gluconate vaginal solution 0.05%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: 4D PET/CT in Diagnosing Participants With Lung and Colorectal Cancer With Liver and Lung Metastasis
Status: COMPLETED
Conditions: Metastatic Malignant Neoplasm in the Liver|Metastatic Malignant Neoplasm in the Lung|Stage IV Colorectal Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8
Interventions: PROCEDURE: 4-Dimensional Computed Tomography|PROCEDURE: 4D PET Scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bangladesh PRODUCTIVity in Eyecare Trial
Status: COMPLETED
Conditions: Diabetic Retinopathy|Diabetic Macular Edema
Interventions: DIAGNOSTIC_TEST: Results utilized from autonomous AI diagnostic system for diabetic retinopathy and/or diabetic macular edema
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Screening for and Responding to Food Insecurity Among Infusion Patients
Status: RECRUITING
Conditions: Cancer|Diet, Healthy|Nutrition, Healthy
Interventions: OTHER: Food pantry referrals|OTHER: No-prep, ready-to-eat meals|OTHER: Vouchers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment for Partial Lesions of the Fingers Flexor Tendons : Tangential Resection or Direct Suture
Status: TERMINATED
Conditions: Flexor Tendon Injury|Lesions Of The Fingers Flexor Tendons
Interventions: PROCEDURE: tangential resection|PROCEDURE: suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Real-time Pressure Volume Loop Monitoring as a Guide for Enhanced Understanding of Changes in Elemental Cardiovascular Physiology During Therapeutic Strategies Aiming for Hemodynamic Optimization. Cohort I: Veno-arterial Extracorporeal Membrane Oxygenation (PLUTO-I)
Status: RECRUITING
Conditions: Extracorporeal Membrane Oxygenation|Cardio/Pulm: Heart Failure
Interventions: OTHER: Pressure-volume loop measurements
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Effects of a New Antidepressant Treatment (GSK561679) in Females With Major Depressive Disorder
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: GSK561679|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Belantamab Mafodotin in Multiple Myeloma Participants With Normal and Impaired Hepatic Function
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Belantamab mafodotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: iCP-NI - Safety, Tolerability, Pharmacokinetic, and Immunogenicity Study in Healthy Male and Female Subjects
Status: SUSPENDED
Conditions: Healthy Volunteers
Interventions: DRUG: iCP-NI|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-GPC3 CAR-T for Treating GPC3-positive Advanced Hepatocellular Carcinoma (HCC)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: Retroviral vector-transduced autologous T cells to express anti-GPC3 CARs|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Self-Management Adherence and Glycemic Control in Older Teens With Type 1 Diabetes: The Teenwork Study
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: Teenwork intervention|BEHAVIORAL: Text message reminders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of ROSE12 Alone and in Combination With Other Anti-tumor Agents in Patients With Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: ROSE12|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Yogurt on Gut Microbiome and Metabolism in H. Pylori.
Status: COMPLETED
Conditions: Probiotic|Gut Microbiota|Helicobacter Pylori Infection|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Yogurt|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of BPI-16350 in Combination With Fulvestrant in Patients With HR+ and HER2- Locally Advanced, Recurrent or Metastatic Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: BPI-16350|DRUG: placebo|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Preventive Vascular Screening Trial of 65-74 Year Old Men in the Central Region of Denmark
Status: UNKNOWN
Conditions: Abdominal Aortic Aneurysms|Peripheral Arterial Disease|Hypertension
Interventions: PROCEDURE: Screening for hypertension, lower limb atherosclerosis and abdominal aortic aneurysm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Evaluation of the Efficacy and Safety of Zinc in Viral Infections
Status: COMPLETED
Conditions: SARS-CoV2 Infection
Interventions: DIETARY_SUPPLEMENT: Zinc|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Neurostimulation Device for Insomnia: A Randomized Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Insomnia|Insomnia Chronic|Sleep
Interventions: DEVICE: Fisher Wallace Neurostimulation Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Nebulized Furosemide & Physical Activity-Related Breathlessness
Status: UNKNOWN
Conditions: Breathlessness
Interventions: OTHER: CWS|DRUG: Furosemide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarker for Transthyretin-Related Familial Amyloidotic Polyneuropathy (BioTRAP)
Status: WITHDRAWN
Conditions: Transthyretin Amyloidosis|Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy|Transthyretin Amyloid Cardiopathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Treatment With Teriparatide and Zoledronic Acid in Patients With Osteogenesis Imperfecta
Status: TERMINATED
Conditions: Osteogenesis Imperfecta
Interventions: DRUG: Zoledronic acid|DRUG: Teriparatide|OTHER: No active treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Bevacizumab vs.Combination Therapy for CNV Due to Other Than AMD
Status: WITHDRAWN
Conditions: Choroidal Neovascularization|Myopia|Punctate Inner Choroidopathy (PIC)|Multifocal Choroiditis|Ocular Histoplasmosis Syndrome|Central Serous Chorioretinopathy (CSC)|Angioid Streaks|Trauma, or Hereditary Eye Diseases
Interventions: DRUG: Bevacizumab (Avastin; Genentech, Inc.)|DRUG: Bevacizumab, Dexamethasone, Verteporfin Photodynamic Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of CBP-201 in Moderate to Severe Atopic Dermatitis in China
Status: COMPLETED
Conditions: Moderate-to-severe Atopic Dermatitis
Interventions: DRUG: CBP-201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Pilot Trial of BHV-4157
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinocerebellar Ataxias|Spinocerebellar Ataxia Type 1|Spinocerebellar Ataxia Type 2|Spinocerebellar Ataxia 3|Spinocerebellar Ataxia Type 6|MSA-C
Interventions: DRUG: BHV-4157
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Thalidomide and Capecitabine in Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Kidney Neoplasms
Interventions: DRUG: Thalidomide|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TherApeutics in Early ProState Cancer (TAPS02)
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Apalutamide Oral Tablet [Erleada]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial To Assess The Safety, Tolerability, And Immunogenicity Of Rlp2086 Vaccine When Administered In Either 2- Or 3-Dose Regimens In Healthy Subjects Aged ≥11 To <19 Years
Status: COMPLETED
Conditions: Meningococcal Vaccine
Interventions: BIOLOGICAL: Vaccine|BIOLOGICAL: Vaccine|BIOLOGICAL: Vaccine|BIOLOGICAL: Vaccine|BIOLOGICAL: Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Anticoagulation on Demand After Percutaneous Coronary Intervention in High Bleeding Risk Patients
Status: UNKNOWN
Conditions: Ischemic Heart Disease|Atrial Fibrillation
Interventions: DRUG: Intermittent administration of dabigatran, rivaroxaban, apixaban, or edoxaban|DRUG: Chronic administration of dabigatran, rivaroxaban, apixaban, or edoxaban
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Recalling and Anticipating Specific Positive Events to Boost Resilience in Adolescents
Status: COMPLETED
Conditions: Specific Positive Memories|Specific Positive Future Events|Resilience|Mental Wellbeing
Interventions: BEHAVIORAL: Positive Events Training (PET)|BEHAVIORAL: CREAtive writing Training (CREAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety, Tolerability, PK, and PD of BMS-986090 in Healthy Subjects
Status: TERMINATED
Conditions: Healthy Adult Volunteers
Interventions: DRUG: BMS-986090|DRUG: Placebo matching with BMS-986090|DRUG: Keyhole limpet hemocyanin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 2 Study to Evaluate the Safety and Efficacy of Max-40279-01 in Patients With Advanced Gastric Cancer or Gastroesophageal Junction Cancer
Status: UNKNOWN
Conditions: Gastric Cancer|Gastroesophageal Junction Cancer
Interventions: DRUG: MAX-40279
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nonpharmacological Management of Postoperative Pain in Children
Status: COMPLETED
Conditions: Orthopedic Disorder|Post Operative Pain
Interventions: OTHER: Group to play online games|OTHER: Group that received cold application|DRUG: Group that received placebo (PHYSIOLOGICAL SALINE ISOTONIC 9 mg/ml AMPULE)|OTHER: Group that played an online game and received cold application at the same time
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Panobinostat in Pediatric Patients With Solid Tumors Including MRT/ATRT
Status: TERMINATED
Conditions: Rhabdoid Tumor|Atypical Teratoid/Rhabdoid Tumor|Malignant Rhabdoid Tumor|Recurrent Brain Tumor, Childhood
Interventions: DRUG: Panobinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate ABT-126 for the Treatment of Cognitive Deficits in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: ABT-126|DRUG: ABT-126|DRUG: ABT-126|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Angiomax in Patients With HIT/HITTS Type II Undergoing Off-Pump Coronary Artery Bypass Grafting (CABG) (CHOOSE)
Status: COMPLETED
Conditions: Thrombocytopenia|Thrombosis|Cardiac Disease|Coronary Artery Bypass Surgery
Interventions: DRUG: Angiomax (bivalirudin) anticoagulant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of BMS-903452 in Healthy Subjects (Panel 1-7) & Relative Bioavailability of the Crystalline and Amorphous Forms of BMS-903452 [Panels 4, 6, 11 & 12(Part A)], and Subjects With Type 2 Diabetes Mellitus (Part B)
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: BMS-903452|DRUG: BMS-903452|DRUG: BMS-903452|DRUG: BMS-903452|DRUG: BMS-903452|DRUG: BMS-903452|DRUG: BMS-903452|DRUG: Placebo|DRUG: Placebo|DRUG: BMS-903452|DRUG: BMS-903452|DRUG: Placebo|DRUG: BMS-903452|DRUG: BMS-903452|DRUG: BMS-903452
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of Methoxy Polyethylene Glycol-Epoetin Beta (Mircera) in Chronic Kidney Disease Participants on Dialysis
Status: COMPLETED
Conditions: Chronic Kidney Diseases
Interventions: DRUG: Methoxy Polyethylene Glycol-Epoetin Beta
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: AXS-05|DRUG: Bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin Type A and Kinesitherapy of Post-stroke Patients
Status: UNKNOWN
Conditions: Stroke
Interventions: PROCEDURE: Botulinum toxin type A and kinesiotherapy|PROCEDURE: Saline and Kinesiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Valproic Acid in Chronic Lymphocytic Leukemia (CLL)
Status: UNKNOWN
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Valproic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pathological Tumor and Lymph Node Responses After Neoadjuvant Immunochemotherapy in Initially-unresectable NSCLC
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer|Immunotherapy|Chemotherapy|Tumour, Residual
Interventions: DRUG: Timing of drug administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Open-label, Randomized, Phase II Study of the Efficacy and Safety of Indisulam (E7070) in Combination With Capecitabine
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: E7070
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neurogenic Detrusor Overactivity Following Spinal Cord Injury or Multiple Sclerosis
Status: COMPLETED
Conditions: Detrusor Muscle Hyperactivity
Interventions: BIOLOGICAL: Botulinum toxin type A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Modified Mathematical Model to Calculate Power Received by Mechanically Ventilated Patients With Different Etiologies
Status: UNKNOWN
Conditions: Acute Respiratory Distress Syndrome, Mechanical Ventilation, Respiratory Mechanics, Ventilator-induced Lung Injury
Interventions: DIAGNOSTIC_TEST: work of breath measurement and calculation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized EsophyX Versus Sham / Placebo Controlled TIF Trial: The RESPECT Study
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease|Hiatal Hernia
Interventions: DEVICE: TIF Transoral Fundoplication|OTHER: Sham placebo procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: In Vivo and In Vitro Efficacy of Artemisinin Combination Therapy
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Artesunate|DRUG: Artemether Lumefantrine|DRUG: Mefloquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Treatment Based on Epidermal Growth Factor Receptor Mutations and Level of BRCA1 Expression in Advanced Adenocarcinoma
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Docetaxel|DRUG: Cisplatin|DRUG: Gemcitabine|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study Evaluating the Safety and Pharmacokinetics of ABBV-075 in Subjects With Cancer
Status: COMPLETED
Conditions: Cancer|Breast Cancer|Non-Small Cell Lung Cancer|Acute Myeloid Leukemia (AML)|Multiple Myeloma|Prostate Cancer|Small Cell Lung Cancer|Non-Hodgkins Lymphoma
Interventions: DRUG: ABBV-075|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amiloride Hydrochloride as an Effective Treatment for ADHD
Status: TERMINATED
Conditions: ADHD
Interventions: DRUG: amiloride|BEHAVIORAL: Behavioral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Implantable Collamer Lens Versus Implantable Phakic Lens IPCL in Myopic Patients; A Comparative Study
Status: COMPLETED
Conditions: Myopia
Interventions: PROCEDURE: Implantable Collamer Lens (ICL)|PROCEDURE: Implantable Intraocular Lens (IPCL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prognostic Value of Precision Medicine in Patients With MINOCA (PROMISE Trial).
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocardial Infarction With Non-Obstructive Coronary Arteries
Interventions: PROCEDURE: Coronary angiography|DIAGNOSTIC_TEST: OCT imaging|PROCEDURE: Percutaneous coronary intervention (PCI):|DIAGNOSTIC_TEST: Acetylcholine provocative test|DIAGNOSTIC_TEST: TT-Echocardiography|DIAGNOSTIC_TEST: TE/contrast echocardiography|DIAGNOSTIC_TEST: Cardiac magnetic resonance|DIAGNOSTIC_TEST: Circulating biomarkers|DRUG: Antiplatelet Drug|DRUG: Statin|DRUG: Beta blocker|DRUG: ACEi/ARB|DRUG: CCB|DRUG: Nitrates|DRUG: Anticoagulant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photorefractive Intrastromal Corneal Crosslinking as a Treatment for Low Grade Myopia
Status: COMPLETED
Conditions: Myopia|Corneal Crosslinking|Refractive Errors|Eye Diseases
Interventions: PROCEDURE: 4.0 mm treatment|PROCEDURE: 3.5 mm treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Small Circulating RNA as Molecular Markers of Lung Disease in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: OTHER: miRNAs isolation from blood samples of patients and control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Exploring Safety, Pharmacokinetic and Pharmacodynamic of BN82451 in Male Huntington's Disease Patients
Status: TERMINATED
Conditions: Huntington's Disease
Interventions: DRUG: BN82451B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT