pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: AXS-05 Phase II Trial on Smoking Behavior
Status: COMPLETED
Conditions: Smoking Cessation|Smoking, Cigarette|Nicotine Dependence
Interventions: DRUG: AXS-05|DRUG: Bupropion SR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Use of Viscoelastic Tests in the Treatment of Traumatic Induced Coagulopathy: a Pragmatic Randomized Clinical Trial.
Status: WITHDRAWN
Conditions: Trauma, Multiple|Coagulopathy|Massive Hemorrhage
Interventions: PROCEDURE: Trauma-induced coagulopathy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methylphenidate for Depressed Cancer Patients Receiving Palliative Care
Status: COMPLETED
Conditions: Depression|Palliative Care|Cancer|Mental Disorder
Interventions: DRUG: Methylphenidate|DRUG: Placebo|DRUG: Selective Serotonin Uptake Inhibitor (SSRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Propranolol, Carvedilol and Rosuvastatin in the Prevention of Variceal Bleeding in Cirrhotic Portal Hypertension
Status: UNKNOWN
Conditions: Cirrhosis|Portal Hypertension|Variceal Hemorrhage
Interventions: DRUG: Propranolol|DRUG: Carvedilol|DRUG: Rosuvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of 6 Weeks Daily Consumption of a Cereal-based Juice Beverage on Gastrointestinal Health
Status: COMPLETED
Conditions: Irritable Bowel
Interventions: DIETARY_SUPPLEMENT: Barley β-glucan|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Positron Emission Tomography (PET) Study
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD1446|RADIATION: 2-[18F]-F-A85380
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Structured Exercise Prescription Program in Obese Children
Status: UNKNOWN
Conditions: Obesity|Exercise|Cardiovascular Risk Factor|Liver Diseases|Metabolic Syndrome|Childhood Obesity
Interventions: OTHER: Personalized structured exercise program|OTHER: Non personalized non-structured exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0215 Trastuzumab, Docetaxel, Vinorelbine, and Filgrastim in Treating Women With Stage IV Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: trastuzumab|DRUG: docetaxel|DRUG: vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tack Optimized Balloon Angioplasty Post-Market Study
Status: TERMINATED
Conditions: PAD - Peripheral Arterial Disease|PAD|Dissection|Arterial Dissection|Peripheral Arterial Disease|Peripheral Vascular Diseases
Interventions: DEVICE: The Tack Endovascular System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate SAGE-217 for Prevention of Relapse in Adult Participants With Major Depressive Disorder
Status: TERMINATED
Conditions: Major Depressive Disorder
Interventions: DRUG: SAGE-217|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: JSI-1187-01 Monotherapy and in Combination With Dabrafenib for Advanced Solid Tumors With MAPK Pathway Mutations
Status: SUSPENDED
Conditions: Solid Tumors
Interventions: DRUG: JSI-1187|DRUG: Dabrafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin on Blood Pressure Variability and Ambulatory Arterial Stiffness Index in Hypertension
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: Dapagliflozin|DRUG: Placebo - Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficiency of Laparoscopic Management of Intra-canalicular (Emergent) Testis
Status: COMPLETED
Conditions: Testes Undescend
Interventions: PROCEDURE: laparoscopic orchiopexy for intra-canalicular testis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Safety and Efficacy of High Dose of Symbicort® SMART in Japanese Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Symbicort Turbuhaler|DRUG: Terbutaline Turbuhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HDR Brachytherapy vs SABR in Early-intermediate Prostate Cancer
Status: RECRUITING
Conditions: Biochemical Relapse Free Survival|Complications Rates (Erectile Dysfunction, GI, GU Complications)
Interventions: RADIATION: Stereotactic ablative radiotherapy|RADIATION: High dose rate brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reassessment of myocardIAL Bridge TOwards PeRsOnalized Medicine
Status: RECRUITING
Conditions: Myocardial Bridge
Interventions: DIAGNOSTIC_TEST: "full-physiology approach" arm|DIAGNOSTIC_TEST: "standard approach" arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Assess the Safety and Pharmacokinetics of ADASUVE® at Doses of 2.5, 5, or 10 mg in Children and Adolescents (10 Through 17 Years of Age) With Any Condition Warranting Chronic Use of an Antipsychotic Medication
Status: COMPLETED
Conditions: BiPolar
Interventions: DRUG: ADASUVE®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 1 Thorough QT Study in Young Healthy Volunteers
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: SKY0402|DRUG: Moxifloxacin 400mg|DRUG: Placebo injection|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Steam Ablation Versus Endovenous Laser Ablation for the Treatment of Great Saphenous Veins
Status: COMPLETED
Conditions: Varicose Veins|Varicose Veins of Leg With Long Saphenous Vein Distribution
Interventions: PROCEDURE: Endovenous laser ablation with 940 nm bare fiber|PROCEDURE: Endovenous steam ablation with steam vein sclerosis system.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of Inhaled Tranexamic Acid for the Treatment of Pulmonary Hemorrhage in Cancer Patients
Status: RECRUITING
Conditions: Pulmonary Hemorrhage|Cancer
Interventions: DRUG: tranexamic acid|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Personalized Approach to Effects of Affective Bias Modification on Symptom Change and Rumination
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Affective bias modification|BEHAVIORAL: Sham Affective bias modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Cycle Control Europe
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: EV/DNG (Qlaira, BAY86-5027, SH T00658K)|DRUG: SH D 593 B (Miranova)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pulsed Electromagnetic Field Therapy on Muscle Strength and Function in Patients With End-stage of Knee Osteoarthritis
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DEVICE: PEMF|OTHER: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Neuromuscular Electrical Stimulation Versus Cycle Ergometer Training in a Pulmonary Rehabilitation Program
Status: COMPLETED
Conditions: COPD
Interventions: DEVICE: neuromuscular electrical stimulation|DEVICE: cycle ergometer training|OTHER: Conventional pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TMS for the Treatment of Primary Progressive Aphasia
Status: RECRUITING
Conditions: Logopenic Variant Primary Progressive Aphasia|Non-fluent Variant Primary Progressive Aphasia|Semantic Variant Primary Progressive Aphasia
Interventions: DEVICE: ACTIVE rTMS|DEVICE: SHAM rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Multicenter Phase II Study to Evaluate the Clinical Activity and the Safety Profile of Everolimus in Marginal Zone B-cell Lymphomas (MZL)
Status: COMPLETED
Conditions: Marginal Zone B-cell Lymphoma
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of PRECEDE Model for Health Education on Changes and Level of Control in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Cardiovascular Risk Factor
Interventions: BEHAVIORAL: PRECEDE HPE model|BEHAVIORAL: CHPE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Intranasal Insulin Administration on Cognitive Function After Cardiac Surgery.
Status: UNKNOWN
Conditions: Cognitive Decline|Heart Diseases|Delirium
Interventions: DRUG: Regular insulin|DRUG: Normal Saline Flush, 0.9% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating Vertebroplasty and Kyphoplasty for Reducing Trauma-related Fractures
Status: WITHDRAWN
Conditions: Vertebral Body Compression Fractures
Interventions: PROCEDURE: Kyphoplasty|PROCEDURE: Vertebroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Interleukin-1 Beta Targeted Therapy for Patients Suffering From Allergic Contact Dermatitis
Status: UNKNOWN
Conditions: Allergic Contact Dermatitis
Interventions: DRUG: Anakinra|DRUG: Sodium Chloride 9mg/ml Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A5288/MULTI-OCTAVE: Management Using Latest Technologies to Optimize Combination Therapy After Viral Failure
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Darunavir|DRUG: Etravirine|DRUG: Emtricitabine/tenofovir disoproxil fumarate|DRUG: Raltegravir|DRUG: Second line ART regimens - based on a boosted protease inhibitor (bPI) plus two nucleoside analogues (NRTIs)|DRUG: Study provided drugs according to patient resistance profile (DRV, ETR, RTV, FTC/TDF) + any in country available drug as applicable & available|OTHER: SOC adherence versus SOC+CPI adherence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of Cefadroxil From Duricef 1 gm F.C.T (GSK) and Biodroxil 1 gm F.C.T (Novartis Pharma)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cefadroxil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Randomized Trial Evaluating Performance of the Trevo Retriever Versus the Merci Retriever in Acute Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DEVICE: Mechanical Thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety and Efficacy of Once-weekly PEG-somatropin (GenSci004) in Children With Growth Hormone Deficiency
Status: NOT_YET_RECRUITING
Conditions: GHD
Interventions: DRUG: PEG-somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Home Telerehabilitation Program for People With Proximal Humerus Fracture
Status: COMPLETED
Conditions: Humeral Fractures, Proximal
Interventions: OTHER: Rehabilitation (Physiotherapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of Percutaneous Mechanical Thrombectomy Treating Acute Deep Vein Thrombosis of Lower Extremities
Status: RECRUITING
Conditions: Pharmacomechanical Thrombolysis|Deep Vein Thrombosis
Interventions: PROCEDURE: Pharmacomechanical thrombolysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lactobacillus Rhamnosus GG: Interaction With Human Microbiota and Immunity
Status: COMPLETED
Conditions: Gut Microbiota|Skin Microbiota|Humoral Immune Responses|Severity of Atopic Dermatitis
Interventions: DIETARY_SUPPLEMENT: Casein hydrolysate added with LGG|DIETARY_SUPPLEMENT: Infants drink casein hydrolysate without LGG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acupoint Application on Postoperative Ileus
Status: UNKNOWN
Conditions: Postoperative Ileus
Interventions: OTHER: Acupoint application|OTHER: Fake acupoint application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Baduanjin Exercise on Meridian Energy and Heart Rate Variability in Patients Undergoing Cardiac Sugery
Status: UNKNOWN
Conditions: Open Heart Surgery
Interventions: BEHAVIORAL: Walk 30mins|BEHAVIORAL: Walk plus Baduanjin|OTHER: usual care|BEHAVIORAL: Baduanjin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hemopatch as a Tool to Prevent Biliary Fistula in Liver Surgery.
Status: COMPLETED
Conditions: Biliary Fistula|Surgery
Interventions: PROCEDURE: Hemopatch|PROCEDURE: Fribrin glue and Tabotamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Oral Dexmedetomidine for Parental Separation in Pediatrics Undergoing Adenotonsillectomy
Status: COMPLETED
Conditions: Adenotonsillectomy
Interventions: DRUG: Dexmedetomidine|COMBINATION_PRODUCT: Midazolam/Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Using AI and Peer Coaching to Address Racial Disparities Among People Who Use Opioids
Status: NOT_YET_RECRUITING
Conditions: Opioid Use Disorder
Interventions: BEHAVIORAL: PRC supported text + AI driven SDH-enhanced text|BEHAVIORAL: AI driven SDH-enhanced text only|BEHAVIORAL: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nebulized 3% Hypertonic Saline in the Treatment of Acute Bronchiolitis in the Emergency Department
Status: WITHDRAWN
Conditions: Acute Bronchiolitis
Interventions: DRUG: 3% saline + oral placebo|DRUG: 0.9% saline + oral dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adaptive RADiation Therapy With Concurrent Sacituzumab Govitecan (SG) for Muscle Invasive Bladder Cancer
Status: RECRUITING
Conditions: Localized Muscle Invasive Bladder Urothelial Carcinoma|Muscle-Invasive Bladder Carcinoma
Interventions: DRUG: Sacituzumab govitecan|RADIATION: Adaptive Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A fMRI(Functional Magnetic Resonance Imaging) Research Study to Learn More About Multiple Sclerosis and Individuals Potentially Experiencing Memory Difficulties
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: Donepezil HCI (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Brief Community Linkage Intervention for Dually Diagnosed Individuals
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorders|Substance-Related Disorders|Bipolar Disorder
Interventions: BEHAVIORAL: Time limited case management|BEHAVIORAL: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Liposomal Bupivacaine vs Bupivacaine for Pain Control After Sternotomy
Status: UNKNOWN
Conditions: Pain Management|Sternotomy
Interventions: DRUG: Exparel|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Aesthetic Outcome of Lithium Disilicate (e.Max) All Ceramic Crowns on Titanium Implant Abutments in the Aesthetic Zone After Different Color Masking Approaches
Status: UNKNOWN
Conditions: Aesthetic Outcome of Crowns on Implants
Interventions: OTHER: opaqued titanium abutments|OTHER: lithium disilicate coping (high opacity)|OTHER: titanium abutment with no color masking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PediCRaFT: Pediatric Crohn's Disease Fecal Transplant Trial
Status: COMPLETED
Conditions: Crohn Disease|Pediatric Crohns Disease|Inflammatory Bowel Diseases|Colitis
Interventions: BIOLOGICAL: MICROBIOTA|BIOLOGICAL: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ticagrelor Versus Cilostazol in Ischemic Stroke
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: DRUG: Ticagrelor 90 MG|DRUG: Cilostazol 100 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study to Evaluate the Safety and Effectiveness of Implantation of Flowise Cerebral Flow Diverter (Flowise)
Status: COMPLETED
Conditions: Intracranial Aneurysm
Interventions: DEVICE: Flowise Cerebral Flow Diverter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ISABel: Intelligent Sleep Apnoea Bed
Status: TERMINATED
Conditions: Effect of ISABel Bed 1 Ans ISABel Bed 2
Interventions: DEVICE: ISABel Bed 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Second-generation AI Based Therapeutic Regimen in Patients With Gaucher Disease Treated With Enzyme Replacement Therapy.
Status: COMPLETED
Conditions: Gaucher Disease Type 1
Interventions: COMBINATION_PRODUCT: Enzyme replacement therapy for Gaucher disease in combination with altus care application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Functional Results and Survival Rate of Peroneus Longus Tendon - PLT and Hamstring Tendon - HT Used for Reconstruction of the Anterior Cruciate Ligament.
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Injuries|Anterior Cruciate Ligament Rupture|Anterior Cruciate Ligament Tear|Knee Injuries|Knee Ligament Injury
Interventions: PROCEDURE: ACL Reconstruction using an autograph of the peroneus longus tendon, folded twice.|PROCEDURE: ACL Reconstruction using an autograph of Hamstrings muscle tendons.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of AMG 073 in Hemodialysis Subjects
Status: COMPLETED
Conditions: Hyperparathyroidism
Interventions: DRUG: Placebo|DRUG: AMG 073
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: KurCoSmart Effects on People With Type 2 DM
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Insulin Resistance|Inflammation|Body Weight
Interventions: DIETARY_SUPPLEMENT: Curcumin and virgin coconut oil extract (KurCo Smart)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-finding Study of ASP4070
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: DRUG: ASP4070|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Vi-CRM197 Vaccine Against S. Typhi in Children, Older Infants and Infants
Status: COMPLETED
Conditions: Typhoid Fever
Interventions: BIOLOGICAL: Vi-CRM197 vaccine|BIOLOGICAL: Pneumococcal conjugate vaccine|BIOLOGICAL: Vi Polysaccharide (PS) vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Recombinant Erythropoietin on Numbers of Circulating Endothelial Progenitor Cells in Subacute TBI
Status: WITHDRAWN
Conditions: Traumatic Brain Injury
Interventions: DRUG: Erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Non Inferiority Trial of Locally Manufactured Rabies Vaccine 'Rabix-VC' in Bangladesh
Status: UNKNOWN
Conditions: Non Inferiority Trial
Interventions: DRUG: Rabix-VC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Epidemiology and Long-term Outcome of Patients With VHD
Status: COMPLETED
Conditions: Valvular Disease|Valvular Heart Disease|Aortic Valve Stenosis|Mitral Insufficiency and Aortic Stenosis|Mitral Stenosis|Coronary Artery Disease|Chronic Kidney Diseases
Interventions: PROCEDURE: Innovative medical technologies in invasive cardiology and cardiac surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Methylprednisolone After Split-course Chemoradiotherapy For Bulky Local Advanced None-small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: RADIATION: chest radiation|DRUG: concurrent chemotherapy|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Intervention for College Students With ADHD
Status: RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Mindfulness Awareness Practices for ADHD (adapted)|BEHAVIORAL: Services-As-Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acid-Base Composition With Use of hemoDialysates
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DEVICE: Group 1: GranuFlo|DEVICE: Group 2: NaturaLyte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Study on Adjuvant Therapy of TQB3616 Combined With Endocrine Therapy Compared With Placebo Combined With Endocrine Therapy in Patients With Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: TQB3616 capsules, Letrozole, Anastrozole, Tamoxifen|DRUG: Placebo capsules, Letrozole, Anastrozole, Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: Lebrikizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of TATE and PD-1 Inhibitor in Liver Cancer
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Gastric Cancer
Interventions: DRUG: Nivolumab Injectable Product|COMBINATION_PRODUCT: Trans-arterial tirapazamine embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SAINT: Safe Induction of Labor Trial
Status: RECRUITING
Conditions: Labor Complication|Induced; Birth|Pregnancy Related
Interventions: DRUG: Buscopan 20 MG/ML Injectable Solution|DRUG: Sodium bicarbonate|DRUG: Placebo|DRUG: Nacl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Venetoclax Plus R-ICE Chemotherapy for Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B-cell-lymphoma
Interventions: DRUG: Venetoclax|DRUG: Rituximab|DRUG: Ifosfamide|DRUG: Carboplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study of Abdominal Ultrasound (FAST) in Children With Blunt Torso Trauma
Status: RECRUITING
Conditions: Blunt Trauma to Abdomen|Wounds and Injuries|Abdomen Injury|Abdominal Injury|Abdomen, Acute
Interventions: DIAGNOSTIC_TEST: Focused Assessment with Sonography for Trauma (FAST) Examination|OTHER: No Intervention: Standard of Care - Without the FAST Examination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effectiveness of Transvaginal Radiofrequency in Women With Stress Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence,Stress|Pelvic Floor Disorders|Urinary Incontinence|Pelvic Floor Muscle Weakness
Interventions: DEVICE: RF + PFMT|OTHER: PFMT + Placebo RF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Massage of the Low Back Muscles Assessed With Ultrasound Scanning
Status: UNKNOWN
Conditions: Myofascial Pain Syndrome
Interventions: PROCEDURE: Specific massage for fascial release|OTHER: Quiet non-instructed rest for 3 minutes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Avatrombopag for the Treatment of Thrombocytopenia in Pediatric Subjects With Immune Thrombocytopenia for ≥6 Months
Status: ACTIVE_NOT_RECRUITING
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Avatrombopag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Two Different Forms of PF-07081532 in Adults Who Are Overweight or Obese
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DRUG: Formulation A (PF-07081532 20 mg plus 60 mg)|DRUG: Formulation B (PF-07081532 80 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Trial of Regenexx Stem Cell Support Formula
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: Stem Cell Support Formula|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Two Cementing Techniques of the Femoral Component in a Hip Prosthesis
Status: COMPLETED
Conditions: Osteoarthritis, Hip
Interventions: PROCEDURE: line-to-line reaming and cementing technique|PROCEDURE: standard over-reaming with 2 broach sizes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lactobacillus Plantarum 3547 Effects Over Inflammatory and Immunologic Markers
Status: COMPLETED
Conditions: VOLUNTEERS
Interventions: OTHER: Lactobacillus plantarum 3547|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ib Study of FURMONERTINIB in Patients With NSCLC Having Exon 20 Insertion Mutation
Status: WITHDRAWN
Conditions: NSCLC
Interventions: DRUG: Furmonertinib 240mg|DRUG: Furmonertinib 160mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three Levels of Force Application for Maxillary Protraction
Status: COMPLETED
Conditions: Skeletal Class 3 Malocclusion Due to Maxillary Deficiency
Interventions: DEVICE: Petit typeface mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azacitidine Plus PD-1 Therapy for R/R Hodgkin Lymphoma
Status: RECRUITING
Conditions: Relapsed Classic Hodgkin Lymphoma|Refractory Classic Hodgkin Lymphoma
Interventions: DRUG: Azacitidine Plus PD-1 therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PG2 Injection 500 mg in Acute Stroke Study (Pass)
Status: COMPLETED
Conditions: Acute Stroke
Interventions: DRUG: PG2|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of Ketoacidosis During the Perioperative Period: an Observational Study 'The DKAP Study'
Status: COMPLETED
Conditions: Ketosis|Keto Acidosis|Ketoses, Metabolic|Ketosis, Diabetic|Peri-operative|Diabetes Mellitus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Asthma Clinical Research Network (ACRN) Trial - Long-Acting Beta Agonist Response by Genotype (LARGE)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: salmeterol|DRUG: beclomethasone HFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Look at How Safe NNC0268-0965 is in People With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: NNC0268-0965|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Antibody GSK1070806 in the Treatment of Patients With Moderate to Severe Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: DRUG: GSK1070806|DRUG: Placebo- sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers for Neoadjuvant Pembrolizumab in Non-Metastatic Prostate Cancer Positive by 18FDG-PET Scanning
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Administration of Donor Multi TAA-Specific T Cells for AML or MDS (ADSPAM)
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: BIOLOGICAL: MultiTAA-specific T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)
Status: RECRUITING
Conditions: Malignant Solid Neoplasm
Interventions: OTHER: Best Practice|OTHER: Financial Navigation|OTHER: Interview|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of 12 Weeks Treatment With Tadalafil vs Placebo on Lower Urinary Tract Symptoms
Status: COMPLETED
Conditions: Prostatic Hyperplasia|Lower Urinary Tract Symptoms
Interventions: DRUG: Tadalafil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Daily Light Exposure for Sleep Disturbance, Fatigue, and Functional Outcomes in Acute Brain Injury
Status: UNKNOWN
Conditions: Stroke|Traumatic Brain Injury|Non-traumatic Brain Injury
Interventions: OTHER: Philips GoLite Blu HF3429/60|OTHER: Philips LivingColor Aura 70998/60/48
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Biomechanical Assessment of Load Applied on Residuum of Individuals With Limb Loss Fitted With a Prosthetic Limb
Status: RECRUITING
Conditions: Prosthesis User|Amputation
Interventions: DEVICE: Power Knee with bone anchored suspension|DEVICE: C-Leg|DEVICE: Rheo Knee XC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase Ib/II Study of Carboplatin + M6620 + Avelumab in PARPi-resistant Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: M6620|DRUG: Avelumab|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of Medicaments Used After Free Gingival Graft on Postoperative Complications.
Status: COMPLETED
Conditions: Pain, Postoperative|Healing Wound|Hemorrhage|Analgesia
Interventions: DRUG: Majezik %0.25 oral spray|OTHER: Aftamed oral spray|OTHER: Crystalin oral spray|PROCEDURE: Free gingival graft harvesting
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of a New Bone Conduction Hearing System to a Osteo-integrated Bone Conduction Hearing Aid on a Softband
Status: WITHDRAWN
Conditions: Conductive Hearing Loss
Interventions: DEVICE: ADHEAR and PONTO 3 SUPER POWER on softband hearing aids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate Safety and Efficacy of Elagolix in Participants With Endometriosis With Associated Moderate to Severe Pain
Status: TERMINATED
Conditions: Endometriosis
Interventions: DRUG: elagolix|DRUG: estradiol/norethindrone acetate (E2/NETA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cochlear Implants in Young Children With SSD
Status: RECRUITING
Conditions: Single Sided Deafness|Unilateral Deafness|Hearing Loss, Unilateral|Hearing Loss|Congenital Hearing Loss|Deafness One Ear
Interventions: DEVICE: Cochlear Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Extracorporeal Lung Assist to Avoid Intubation in Patients Failing Noninvasive Ventilation for Hypercapnic ARF
Status: COMPLETED
Conditions: Hypercapnia|Respiratory Insufficiency
Interventions: DEVICE: vv-ECCO2R (Novalung GmbH, Germany)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Immunogenicity of V419 Given Concomitantly With Prevnar 13™ and RotaTeq™ (V419-005)
Status: COMPLETED
Conditions: Bacterial Infections|Virus Diseases
Interventions: BIOLOGICAL: V419|BIOLOGICAL: DAPTACEL™|BIOLOGICAL: PedvaxHIB™|BIOLOGICAL: Prevnar 13™|BIOLOGICAL: RotaTeq™|BIOLOGICAL: PENTACEL™|BIOLOGICAL: Recombivax HB vaccine|BIOLOGICAL: ActHIB™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sleep Disordered Breathing in Transient Ischemic Attack (TIA)/Ischemic Stroke and Continuous Positive Airway Pressure (CPAP) Treatment Efficacy
Status: UNKNOWN
Conditions: TIA|Ischemic Stroke
Interventions: OTHER: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: MRI-Guided Brachytherapy in Treating Participants With HPV-Associated Stage IB2-IVA Cervical or Stage II-IVA Vaginal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Papillomavirus-Related Carcinoma|Human Papillomavirus-Related Cervical Carcinoma|Stage IB2 Cervical Cancer AJCC v8|Stage II Cervical Cancer AJCC v8|Stage II Vaginal Cancer AJCC v8|Stage IIA Cervical Cancer AJCC v8|Stage IIA Vaginal Cancer AJCC v8|Stage IIA1 Cervical Cancer AJCC v8|Stage IIA2 Cervical Cancer AJCC v8|Stage IIB Cervical Cancer AJCC v8|Stage IIB Vaginal Cancer AJCC v8|Stage III Cervical Cancer AJCC v8|Stage III Vaginal Cancer AJCC v8|Stage IIIA Cervical Cancer AJCC v8|Stage IIIB Cervical Cancer AJCC v8|Stage IVA Cervical Cancer AJCC v8|Stage IVA Vaginal Cancer AJCC v8
Interventions: RADIATION: Internal Radiation Therapy|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Response Patterns to the Electric Stimulation of Epidural Catheters in Term Pregnant Women
Status: COMPLETED
Conditions: Labor Pain
Interventions: DEVICE: Trans-catheter electric stimulation test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prediction of Late Fetal Growth Restriction Using Cerebroplacental Ratio
Status: UNKNOWN
Conditions: Fetal Growth Retardation|Stillbirth|Neonatal Respiratory Failure|Neonatal Death
Interventions: DIAGNOSTIC_TEST: Biophsical profile|DIAGNOSTIC_TEST: Cerebroplacental ratio
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Dose Escalation Trial of Radiation Therapy (RT) for Hepatocellular Carcinoma (HCC)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: 3DCRT or IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Naltrexone and Behavioral Drug and HIV Risk Reduction Counseling in Russia
Status: COMPLETED
Conditions: Opiate Dependence
Interventions: DRUG: Vivitrol|DRUG: Naltrexone (oral)|BEHAVIORAL: BDRC|BEHAVIORAL: Medical Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate How Well Single and Multiple Doses of GLPG4399 Are Tolerated in Healthy, Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG4399 oral suspension|DRUG: GLPG4399 capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ENCOMPASS: Expansion Study C
Status: COMPLETED
Conditions: Hypertension|Diabetes Mellitus, Type 2|Chronic Kidney Diseases|Ischemic Heart Disease|Congestive Heart Failure|Chronic Obstructive Pulmonary Disease|Asthma
Interventions: BEHAVIORAL: Community Health Navigator Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Duodenal Mucosal Resurfacing in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Diabetes Mellitus
Interventions: DEVICE: DMR Procedure (Fractyl)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Study of OKI-219 in Advanced Solid Tumors and Advanced Breast Cancer
Status: RECRUITING
Conditions: Advanced Cancer|Breast Cancer
Interventions: DRUG: OKI-219|DRUG: Fulvestrant|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 3 Versus 10 Days of Antibiotics in Skin Abscesses After Surgical Drainage
Status: COMPLETED
Conditions: Skin Disease, Bacterial|Abscess
Interventions: DRUG: Trimethoprim-Sulfamethoxazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Case Management to Improve the Outpatient Care of Alcohol-related Disorders
Status: COMPLETED
Conditions: Alcohol-related Disorders
Interventions: PROCEDURE: Online Comprehensive Quality Management System (CQM) of alcohol-related disorders in primary care|PROCEDURE: Physician training|PROCEDURE: Practice team training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Inhaled Apocynin Decreases Reactive Oxygen Species Concentrations in Exhaled Breath Condensate in Mild Asthmatics
Status: COMPLETED
Conditions: Bronchial Asthma
Interventions: DRUG: Apocynin nebulization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy and Safety of Wound Dressing Solution Containing EGF in Patients With Peptic Ulcers Bleeding
Status: COMPLETED
Conditions: Peptic Ulcer Bleeding
Interventions: DEVICE: CEGP003|DEVICE: Injection Tx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Endovascular Recanalization for Acute Basilar Artery Occlusion With Extended Time Window (ANGEL-BAO)
Status: RECRUITING
Conditions: Acute Ischemic Stroke|Basilar Artery Occlusion
Interventions: DRUG: Best medical management|PROCEDURE: Endovascular treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Limbal Stem Cell Derived Exosome (LSC-Exo) Eye Drop for Treatment of Dry Eye
Status: RECRUITING
Conditions: Dry Eye Syndromes
Interventions: BIOLOGICAL: Limbal Stem Cell Derived Exosomes Eye Drop
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Randomized, Placebo-Controlled, Double-Blind Trial to Evaluate the Safety and Immunogenicity of a Recombinant Vaccinia-HIV-1 IIIB Env/Gag/Pol Vaccine (TBC-3B)
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: TBC-3B Vaccine|BIOLOGICAL: Smallpox Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The Effect of a New Specific Enteral Formula Compared to a Standard Formula on the Tolerability of a Combined Radio- and Chemotherapy in Cancer Patients
Status: COMPLETED
Conditions: Enteral Nutrition
Interventions: DIETARY_SUPPLEMENT: Supportan(R) (Disease-specific enteral tube feed, food for special medical purposes)|DIETARY_SUPPLEMENT: Fresubin(R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: DZP|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT