pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Androgen Suppression and Radiation With/Out Docetaxel in High-Risk Localized Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: bicalutamide|DRUG: buserelin|DRUG: flutamide|DRUG: goserelin|DRUG: leuprolide acetate|PROCEDURE: neoadjuvant therapy|PROCEDURE: quality-of-life assessment|RADIATION: radiation therapy|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Multi-center, Single-arm Study to Assess the Safety of Retrieval of the Recovery G2 Filter.
Status: COMPLETED
Conditions: Pulmonary Embolism|Venous Thromboembolic Disease
Interventions: DEVICE: Bard Recovery G2 Filter System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of DE With IPL in Combination With DQS
Status: COMPLETED
Conditions: Dry Eye
Interventions: DEVICE: Intense pulsed light|DRUG: Diquafosol tetrasodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bisacodyl Use in the Post-operative Care of Obstetrical/Gynecological (OB/GYN) Patients
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting|Abdominal Pain
Interventions: DRUG: Bisacodyl|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrapure Water System for Hemodialysis Therapy
Status: UNKNOWN
Conditions: The Change of Biomarkers CRP, CBC With the Use of Ultra Pure Water System for|Hemodialysis.|The Rate of Adverse Events Such as Hypotension During Hemodialysis Therapy With Ultra Pure Water|System as Compared to Conventional Water System.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inhaled Iloprost and Exercise Hemodynamics and Ventricular Performance in Heart Failure With Preserved Ejection Fraction
Status: UNKNOWN
Conditions: Heart Failure With Normal Ejection Fraction
Interventions: DRUG: Iloprost|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Olezarsen Administered Subcutaneously to Participants With Severe Hypertriglyceridemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Severe Hypertriglyceridemia
Interventions: DRUG: Olezarsen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate a Drug (Dasotraline) on the Safety, Effectiveness and How Well the Body Tolerates it, in Adults With Moderate to Severe Binge Eating Disorder
Status: COMPLETED
Conditions: Binge Eating Disorder
Interventions: DRUG: dasotraline 4mg|DRUG: dasotraline 6mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Avatrombopag for Chemotherapy-induced Thrombocytopenia
Status: RECRUITING
Conditions: Chemotherapy-induced Thrombocytopenia|Avatrombopag
Interventions: DRUG: Avatrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Nano-hydroxyapatite and LASER on Dentin Hypersensitivity
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: OTHER: Laser|OTHER: nano-hydroxyapatite|OTHER: Laser + nano-hydroxyapatite|OTHER: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Serum and Tissue Cefazolin Concentrations in Patients Undergoing Cesarean Delivery
Status: COMPLETED
Conditions: Cesarean Delivery|Wound Infection|Obesity
Interventions: DRUG: cefazolin|DRUG: cefazolin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Temsirolimus and Bevacizumab in Treating Patients With Advanced Endometrial, Ovarian, Liver, Carcinoid, or Islet Cell Cancer
Status: COMPLETED
Conditions: Adult Hepatocellular Carcinoma|Advanced Adult Hepatocellular Carcinoma|Endometrial Serous Adenocarcinoma|Localized Non-Resectable Adult Liver Carcinoma|Lung Carcinoid Tumor|Malignant Pancreatic Gastrinoma|Malignant Pancreatic Glucagonoma|Malignant Pancreatic Insulinoma|Malignant Pancreatic Somatostatinoma|Metastatic Digestive System Neuroendocrine Tumor G1|Ovarian Carcinosarcoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Seromucinous Carcinoma|Ovarian Serous Surface Papillary Adenocarcinoma|Pancreatic Alpha Cell Adenoma|Pancreatic Beta Cell Adenoma|Pancreatic Delta Cell Adenoma|Pancreatic G-Cell Adenoma|Pancreatic Polypeptide Tumor|Recurrent Adult Liver Carcinoma|Recurrent Digestive System Neuroendocrine Tumor G1|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Pancreatic Neuroendocrine Carcinoma|Recurrent Primary Peritoneal Carcinoma|Recurrent Uterine Corpus Carcinoma|Regional Digestive System Neuroendocrine Tumor G1|Stage IIIA Fallopian Tube Cancer|Stage IIIA Ovarian Cancer|Stage IIIA Primary Peritoneal Cancer|Stage IIIA Uterine Corpus Cancer|Stage IIIB Fallopian Tube Cancer|Stage IIIB Ovarian Cancer|Stage IIIB Primary Peritoneal Cancer|Stage IIIB Uterine Corpus Cancer|Stage IIIC Fallopian Tube Cancer|Stage IIIC Ovarian Cancer|Stage IIIC Primary Peritoneal Cancer|Stage IIIC Uterine Corpus Cancer|Stage IV Fallopian Tube Cancer|Stage IV Ovarian Cancer|Stage IV Primary Peritoneal Cancer|Stage IVA Uterine Corpus Cancer|Stage IVB Uterine Corpus Cancer|Uterine Carcinosarcoma
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-operative Pain and Child Behavior of Hall Technique Versus SDF in the Management of Carious Primary Molars: RCT
Status: UNKNOWN
Conditions: Caries
Interventions: DRUG: Silver diamine fluoride|DEVICE: Hall Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Hemostatic and Sealing Agent to Prevent Surgical Complications After Axillary Lymphadenectomy
Status: COMPLETED
Conditions: Seroma
Interventions: PROCEDURE: Standard axillary lymphadenectomy|PROCEDURE: Collagen sponge coated with human coagulation factors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Human CNS Tau Kinetics in Tauopathies
Status: COMPLETED
Conditions: Progressive Supranuclear Palsy (PSP)|Corticobasal Degeneration (CBD)|Frontotemporal Dementia (FTD MAPT Mutation)
Interventions: OTHER: 13C6 Leucine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Social Cognitive Training (SCT) in Recent-onset Psychosis
Status: UNKNOWN
Conditions: Psychosis
Interventions: DEVICE: SocialVille Social Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myocardial Stunning During Hemodialysis: Role of Dialyste Calcium Concentration
Status: COMPLETED
Conditions: Myocardial Stunning|End-stage Renal Disease
Interventions: OTHER: Change the dialysate calcium concentration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Inactivated, Split-Virion Influenza Vaccine Compared With the Reference Vaccine Vaxigrip® in the Elderly
Status: COMPLETED
Conditions: Orthomyxoviridae Infection|Influenza|Myxovirus Infection
Interventions: BIOLOGICAL: Inactivated, split-virion influenza vaccine|BIOLOGICAL: Inactivated, split-virion influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Clinical Efficacy of Ketoprofen, Associated or Not With Omeprazole in Lower Third Molar Removal
Status: COMPLETED
Conditions: Pain|Other Surgical Procedures
Interventions: DRUG: Ketoprofen|DRUG: Ketoprofen and Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Role of Interleukin-6 in Exercise
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Obesity
Interventions: BEHAVIORAL: Sport|DRUG: Tocilizumab|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: MemFlex to Prevent Depressive Relapse
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Autobiographical Memory Flexibility (MemFlex) training|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Propranolol Versus Prednisolone for Treatment of Symptomatic Hemangiomas
Status: TERMINATED
Conditions: Hemangioma of Infancy
Interventions: DRUG: propranolol|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Neu-P11 in Subjects With Primary Insomnia
Status: COMPLETED
Conditions: Insomnia
Interventions: DRUG: Neu-P11|DRUG: Neu-P11 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerance and Efficiency of an Intrabuccal Biological Film to Enhance Oral Dryness Sensation: The "PREDELFI" Clinical Pilot Study
Status: COMPLETED
Conditions: Sicca Syndrome|Xerostomia
Interventions: DEVICE: PREDELFI|DEVICE: CONTROL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SSR240600C Treatment in Women With Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: SSR240600C|DRUG: tolterodine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Efficacy of a Novel Probiotic on the Bacteriome and Mycobiome of Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Novel probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients
Status: RECRUITING
Conditions: Gastrointestinal Cancer|Pancreatic Cancer|Gastric Cancer|Colon Cancer|Rectal Cancer
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Aldesleukin|BIOLOGICAL: anti-KRAS G12D mTCR PBL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Alogliptin Versus Alogliptin and Pioglitazone on Insulin Resistance of Metformin Treated Women With PCOS
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Insulin Resistance
Interventions: DRUG: Vipdomet|DRUG: Incresync
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Discontinuation Study of Lapatinib Versus Placebo in Subjects With Documented Tumor Progression After Chemotherapy, or Where no Approved Therapy Exists
Status: TERMINATED
Conditions: Cancer
Interventions: DRUG: Oral lapatinib tablets or placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke
Status: RECRUITING
Conditions: Acute Cerebral Ischemia
Interventions: DRUG: Sovateltide|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Associated Abdominal Injuries on Clinical and Operative Outcome in Pelvic Injuries
Status: COMPLETED
Conditions: Pelvic Ring Fracture|Acetabular Fracture|Abdominal Trauma|Polytrauma
Interventions: PROCEDURE: osteosynthesis of the pelvis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Topical AR/101 Compared With Placebo, in Accelerating Granulation Tissue Formation of Hard-to-heal Wounds
Status: UNKNOWN
Conditions: Wounds|Other Ulcers Wounds and Skin Problems
Interventions: DRUG: AR/101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of AIV001 on Low Risk Basal Cell Carcinoma
Status: COMPLETED
Conditions: Superficial Basal Cell Carcinoma|Nodular Basal Cell Carcinoma
Interventions: DRUG: AIV001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Micro-surgical Treatment of Gummy Smile
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Tunneling micro-surgical crown lengthening approach using piezo-surgery|PROCEDURE: Micro-surgical crown lengthening approach using Piezosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Fragile-X Associated Tremor/Ataxia Syndrome (FXTAS) With Allopregnanolone
Status: COMPLETED
Conditions: Fragile X-associated Tremor/Ataxia Syndrome
Interventions: DRUG: Allopregnanolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of Pathways Parent-Mediated Early Autism Intervention on Social Attention and Language
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Pathways Intervention|BEHAVIORAL: Parent Education Intervention (PEI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ponatinib Versus Imatinib in Adults With Acute Lymphoblastic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL)
Interventions: DRUG: Ponatinib|DRUG: Imatinib|DRUG: Vincristine|DRUG: Dexamethasone|DRUG: Cytarabine|DRUG: Methotrexate|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Grateful Strides Toward Physical Activity and Well-Being for Black Breast Cancer Survivors
Status: COMPLETED
Conditions: Cancer Survivors|African Americans|Women|Psychology, Positive|Cardiometabolic Syndrome|Exercise|Feasibility Studies|Breast Neoplasm Female
Interventions: BEHAVIORAL: Gratitude Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Progressive Muscle Relaxation Exercises on Pain and Disability After Spinal Surgery
Status: RECRUITING
Conditions: Spinal Stenosis Lumbar
Interventions: OTHER: Progressive Muscle Relaxation Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Pilates Training on Exercise Capacity and Respiratory Muscle Performance in Patients With Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: OTHER: exercise training group|OTHER: control training group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Systemic Concentration of Short-Chain Fatty Acids After Delivery in the Small and Large Intestine of Healthy Volunteers
Status: RECRUITING
Conditions: Systemic Availability|Intestinal Absorption|Metabolism|Short-chain Fatty Acids
Interventions: DIETARY_SUPPLEMENT: SCFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neuroimaging Biomarkers for Predicting rTMS Response in OCD
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Active bilateral DMPFC|DEVICE: Active right-sided OFC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Plus Autologous Dendritic Cell Vaccine in Patients With PD-L1 Negative Advanced Mesothelioma Who Have Failed Prior Therapies
Status: UNKNOWN
Conditions: Mesothelioma, Malignant|PD-L1 Negative|Advanced Cancer|Progressive Disease
Interventions: DRUG: Pembrolizumab|BIOLOGICAL: Autologous dendritic cells|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study in Healthy Subjects, 2*5 mg Tablets Rivaroxaban Versus 1*10 mg Tablet Rivaroxaban
Status: COMPLETED
Conditions: Therapeutic Equivalency
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Rivaroxaban (Xarelto, BAY59-7939)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Shi Style Cervical Mobilization Versus SNAGS in Patients With Cervicogenic Headache
Status: RECRUITING
Conditions: Cervicogenic Headache
Interventions: OTHER: shi style mobilization|OTHER: SNAGS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: I Vaccinate: Testing Multi-Level Interventions to Improve HPV Vaccination
Status: RECRUITING
Conditions: Cervical Carcinoma|Human Papillomavirus-Related Malignant Neoplasm
Interventions: OTHER: Best Practice|OTHER: Educational Intervention|OTHER: Questionnaire Administration|OTHER: Reminder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Quality of Life Comparison in Advanced Non-squamous Non Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-squamous Nonsmall Cell Neoplasm of Lung
Interventions: DRUG: cisplatin pemetrexed|DRUG: carboplatin paclitaxel bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bronkow Program and Lumbar Stabilization Exercises in Chronic Non Specific Low Back Pain
Status: RECRUITING
Conditions: Chronic Low-back Pain|Non Specific Low Back Pain
Interventions: OTHER: Brunkow Exercise Program|OTHER: Lumbar Stabilization Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Among Healthy Children Receiving Fluzone® Influenza Virus Vaccine (2012-2013 Formulation)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluzone®: Influenza Virus Vaccine, No Preservative: Pediatric Dose|BIOLOGICAL: Fluzone®; Influenza Virus Vaccine, No Preservative
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Yellow Fever Virus Vaccine and Immune Globulin Study
Status: COMPLETED
Conditions: Viremia
Interventions: BIOLOGICAL: YF-VAX® plus saline|BIOLOGICAL: 17D YF Vaccine plus Ig,
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Trident® Tritanium™ Acetabular Shell Revision Study
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Hip
Interventions: DEVICE: Trident® Tritanium™ Acetabular Shell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systematic Treatment After Successful Surgical Treatment for Primary Hyperparathyroidism With Strontium Ranelate
Status: COMPLETED
Conditions: Primary Hyperparathyroidism|Osteopenia|Osteoporosis
Interventions: DRUG: Strontium Ranelate + Ca/Vitamin-D|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Intervention Delivered by App Instant Messaging to Increase Use of Effective Contraception Among Young Women in Bolivia
Status: COMPLETED
Conditions: Contraception
Interventions: BEHAVIORAL: Contraceptive instant messages|OTHER: Mobile phone app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Study of Skeletal Muscle Area-based Paclitaxel Infusion in Patients With Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Analysis of the Efficacies in Neoadjuvant Chemotherapy of Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Pirarubicin|DRUG: Docetaxel|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib Plus Tacrolimus and Methotrexate to Prevent Graft Versus Host Disease (GVHD) After Mismatched Allogeneic Non-Myeloablative Blood Stem Cell Transplantation
Status: COMPLETED
Conditions: Hematologic Malignancies
Interventions: DRUG: Bortezomib (Velcade)|DRUG: Tacrolimus|DRUG: Methotrexate|PROCEDURE: blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: NIV-FOB, HFNC-FOB- Comparison of Methods
Status: UNKNOWN
Conditions: Respiratory Failure|Hypoxemia|Hypoxemic Respiratory Failure
Interventions: DEVICE: NIV, HFNO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Phase 1 Pharmacokinetic Study of Tapentadol Prolonged-Release 250 Milligram (mg) Formulation in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tapentadol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liver Fat as a Dietary Target of the Chinese Medical Nutrition Therapy (CMNT) Diet for Treating Type 2 Diabetes With Nonalcoholic Fatty Liver Disease
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: OTHER: CMNT diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluzoparib in Combination With Chidamide or Camrelizumab for HRD Positive HER2 Negative Advanced Breast Cancer
Status: RECRUITING
Conditions: Advanced HER2 Negative Breast Carcinoma|HRD+Breast Cancer
Interventions: DRUG: fluzoparib+chidamide|DRUG: fluzoparib+camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Combined Low- and High- Frequency Stimulation in Peripheral Muscle Function During Hemodialysis
Status: RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: DEVICE: Electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Intersphincteric Resection in Elderly Patients
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: PROCEDURE: Laparoscopic intersphincteric resection|PROCEDURE: Laparoscopic abdomino-perineal procedures
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of EPA in Patients With Type-2 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Diabetes Type 2|Hypertriglyceridemia|Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: EPAVasc|DIETARY_SUPPLEMENT: Corn Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: TReatment of ADC-Refractory Breast CancEr With Dato-DXd or T-DXd: TRADE DXd
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|HER2-low Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: Trastuzumab Deruxtecan|DRUG: Datopotamab Deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Transient Opening of the Blood-brain Barrier (BBB) With the SonoCloud-9
Status: COMPLETED
Conditions: Glioblastoma, Adult
Interventions: DEVICE: SonoCloud-9|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Aspirin and Clopidogrel in the Atrial Fibrillation With Low or Moderate Stroke Risk
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DRUG: Aspirin|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BI-1808 as a Single Agent and With Pembrolizumab (KEYTRUDA® ) in Treatment of Advanced Malignancies(Keynote-D20)
Status: RECRUITING
Conditions: Advanced Malignancies
Interventions: DRUG: BI-1808|DRUG: Pembrolizumab (KEYTRUDA® ) 25 Mg/mL Solution for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RO5045337 in Combination With Doxorubicin in Patients With Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: RO5045337|DRUG: doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy, Safety and Tolerability of Fecal Microbiota Transfer for the Treatment of Patients With Nonalcoholic Steatohepatitis
Status: NOT_YET_RECRUITING
Conditions: Patients With Nonalcoholic Steatohepatitis
Interventions: DRUG: Group 1 or Experimental group|OTHER: Group 2 or Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Intermittent Oral Dosing of ASP1517 in Peritoneal Dialysis Chronic Kidney Disease Patients With Anemia
Status: COMPLETED
Conditions: Peritoneal Dialysis Chronic Kidney Disease Patients With Anemia
Interventions: DRUG: roxadustat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRECISE: A Prospective, Multi-Center Evaluation of the Accuracy of a Novel Continuous Implanted Glucose Sensor
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DEVICE: Continuous Glucose Monitoring Device (Senseonics)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Physical Dosimetry Study and Preliminary Clinical Results of 3D-printing Non Co-planar Template Assisted With CT-guidance for Iodine-125 Seed Brachytherapy in Pelvic Recurrent Rectum Carcinoma After Surgery and External Beam Radiotherapy
Status: COMPLETED
Conditions: Rectum Cancer, Recurrent|Brachytherapy, Radioisotope
Interventions: RADIATION: radioactive Iodine-125 seed implantation under the guidance of 3D template
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Aldosterone Blockade in Acute Heart Failure: An Exploratory Safety Study
Status: WITHDRAWN
Conditions: Acute Heart Failure
Interventions: DRUG: Spironolactone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Survival and Success Rates of 6mm Implants With a Micro-rough Surface After 4.5 - 18.2 Years in Function
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially|Dental Implant Failed|Implant Complication
Interventions: DEVICE: Implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial of Doxycycline in Renal Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease|Cardiorenal Syndrome
Interventions: DRUG: Doxycycline|DRUG: Placebo (for Doxycycline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of KL130008 in Adults With Severe Alopecia Areata
Status: NOT_YET_RECRUITING
Conditions: Alopecia Areata
Interventions: DRUG: KL130008/Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Influence of Various Tidal Volumes on Exhaled Breath Condensate (EBC) in Mechanically Ventilated Patients
Status: COMPLETED
Conditions: Inflammation
Interventions: PROCEDURE: low tidal volume ventilation|PROCEDURE: high tidal volume ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Effect on Glucose Control of AC2993 in Patients With Type 2 Diabetes Mellitus Treated With a Sulfonylurea
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent
Interventions: DRUG: AC2993|DRUG: AC2993|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Biological Potency of Peanut Allergen Extract in Adolescent and Adult Peanut Allergic Subjects
Status: COMPLETED
Conditions: Peanut Allergy
Interventions: DRUG: DBV712 IHRP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Whole Breast Irradiation vs Twice Daily vs. Once Daily Accelerated Partial Breast Irradiation
Status: UNKNOWN
Conditions: Breast Cancer|Radiation Toxicity
Interventions: RADIATION: Once Daily APBI|RADIATION: Twice Daily APBI|RADIATION: Whole Breast Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glycine vs Placebo for the Schizophrenia Prodrome
Status: COMPLETED
Conditions: Schizophrenia Prodrome
Interventions: DRUG: Glycine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Meta-analysis of Low-calorie Sweetened Beverages and Cardiometabolic Outcomes
Status: UNKNOWN
Conditions: Adiposity|Metabolic Syndrome|Type 2 Diabetes|Cardiovascular Diseases|Mortality
Interventions: OTHER: Change in LCSBs Intake|OTHER: Substitute LCSBs for SSBs or Water
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of TACE Versus TACE/TACI Combination in Advanced Hepatocellular Carcinoma With Portal Vein Invasion
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Doxorubicin|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study With Atazanavir Administered With and Without Ritonavir and a Cytochrome P450 Substrate Rosiglitazone
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Rosiglitazone maleate|DRUG: Atazanavir Sulphate|DRUG: Atazanavir Sulphate + Rosiglitazone maleate|DRUG: Atazanavir Sulphate + Ritonavir|DRUG: Atazanavir Sulphate + Ritonavir + Rosiglitazone maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Dabigatran Following Transient Ischemic Attack and Minor Stroke
Status: COMPLETED
Conditions: Transient Ischemic Attack|Minor Ischemic Stroke
Interventions: DRUG: Dabigatran|DRUG: Acetylsalicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Zinc and Vitamin E Supplementation on Short-term Postoperative Outcomes in Cardiac Surgery Patients.
Status: COMPLETED
Conditions: Heart Surgery
Interventions: DIETARY_SUPPLEMENT: Oral zinc + vitamin E|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial To Evaluate the Efficacy of Oral Salsalate in the Treatment of Older Adults With Unexplained Anemia
Status: TERMINATED
Conditions: Anemia
Interventions: DRUG: Salsalate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HALOS: A Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Multiple Ascending Doses of ION582 in Participants With Angelman Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Angelman Syndrome
Interventions: DRUG: ION582
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Arrhythmia Suppression Trial (CAST)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Death, Sudden, Cardiac|Heart Arrest|Heart Diseases|Myocardial Infarction|Myocardial Ischemia|Ventricular Arrhythmia
Interventions: DRUG: encainide|DRUG: flecainide|DRUG: moricizine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Slow Stepwise Propofol TCI Induction for Titration Anesthesia Maintenance
Status: UNKNOWN
Conditions: Target Controlled Infusion|Induction of Anesthesia|Bispectral Index
Interventions: DRUG: Propofol|DRUG: Remifentanil Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial to Evaluate Progression Free Survival With Primary Retroperitoneal Lymph-node Dissection (pRPLND) Only in Patients With Seminomatous Testicular Germ Cell Tumors With Clinical Stage IIA/B (PRIMETEST)
Status: UNKNOWN
Conditions: Stage II A/B Seminomatous Germ Cell Tumors
Interventions: PROCEDURE: Primary retroperitoneal lymph-node dissection (pRPLND)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metronom Continuous Glucose Monitoring System
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Diabete Mellitus
Interventions: OTHER: Metronom CGM device|OTHER: Metronom CGM device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pain Evaluation in Radium-223 Treated Castration Resistant Prostate Cancer Patients With Bone Metastases
Status: COMPLETED
Conditions: Castration-Resistant Prostatic Cancer
Interventions: DRUG: Radium-223 dichloride, (Xofigo, BAY88-8223)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exploratory Study of IMATINIB High Dose in Intermediate Risk Chronic Myeloid Leukemia in Chronic Phase
Status: COMPLETED
Conditions: Myeloid Leukemia, Chronic, Chronic-Phase
Interventions: DRUG: Imatinib Mesilate (Glivec)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Embosphere Microspheres for Embolization of the Geniculate Artery for the Treatment of Pain With Known Moderate to Severe Knee Osteoarthritis
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Embosphere Microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidemiological and Clinical-pathological Factors of Philadelphia-negative Myeloproliferative Neoplasms in Ecuador
Status: COMPLETED
Conditions: Myeloproliferative Neoplasm|Myeloproliferative Syndrome|Myeloproliferative Neoplasm, Unclassifiable|Myeloproliferative Disorders|Myeloproliferative Disease, Not Classified
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pure Single Incision Laparoscopic Distal Gastrectomy (SIDG) Versus Totally Laparoscopic Distal Gastrectomy (TLDG)
Status: COMPLETED
Conditions: Early Gastric Cancer
Interventions: PROCEDURE: Approach Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of D-Chiro-Inositol Treatment in Women With Endometriosis
Status: RECRUITING
Conditions: Endometriosis
Interventions: DIETARY_SUPPLEMENT: D-Chiro-Inositol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Psychoeducation for Suicidal Behavior
Status: RECRUITING
Conditions: Suicide, Attempted|Suicidal Behavior
Interventions: BEHAVIORAL: Interventional group : PEPSUI psychoeducational program|OTHER: Relaxation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacological Recruitment of Endogenous Neural Precursors to Promote Pediatric White Matter Repair: Establishing Correlations Between Visual Outcomes, Saccadic Function and MEG Oscillations in Children With Demyelinating Disorders in Comparison to Healthy Control Children
Status: COMPLETED
Conditions: Demyelinating Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Primary Prevention Patients Receiving An ICD - Systematic Evaluation of ATP
Status: COMPLETED
Conditions: Sudden Cardiac Death
Interventions: DEVICE: Arm 1 (ATP+Shock)|DEVICE: Arm 2 (shock only)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Non-invasive Brain Stimulation in Children With Autism
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Executive Dysfunction|Child Autism
Interventions: DEVICE: Transcranial Direct Current Stimulation (tDCS)|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Aerobic Exercise and Cognitive Training in Seniors at Increased Risk for Alzheimer's Disease
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease
Interventions: BEHAVIORAL: Combined aerobic exercise and cognitive training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: GSK1349572 Drug Interaction Study With Efavirenz
Status: COMPLETED
Conditions: Infections, Human Immunodeficiency Virus and Herpesviridae
Interventions: DRUG: GSK1349572|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Seizure Therapy for the Treatment of Borderline Personality Disorder
Status: COMPLETED
Conditions: Borderline Personality Disorder
Interventions: DEVICE: MagPro MST with Cool TwinCoil|BEHAVIORAL: DBT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Metoclopramide and Ibuprofen for the Treatment of Acute Mountain Sickness
Status: COMPLETED
Conditions: Acute Mountain Sickness|High Altitude Headache
Interventions: DRUG: Ibuprofen|DRUG: Metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: S.I.F.A. II: Prevention Of Thromboembolic Events In Patients With Nonrheumatic Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: indobufen|DRUG: aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Trial of Docetaxel and Gemcitabine Versus Gemcitabine in Elderly Patients With NSCLC
Status: TERMINATED
Conditions: Non-small-cell Lung Cancer
Interventions: DRUG: Docetaxel|DRUG: Gemcitabine|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Fermented Infant Formula in Weaning Babies
Status: COMPLETED
Conditions: Weaning
Interventions: OTHER: Breastmilk|OTHER: Standard milk|OTHER: Fermented milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Bioavailability of Dabigatran and Amiodarone After Multiple Oral Administrations of Dabigatran Etexilate With or Without Amiodarone as Single Dose in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dabigatran etexilate|DRUG: Amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systematic Sampling of Lymph Nodes vs. Lymphadenectomy According to Intraoperative Frozen Pathology for Pulmonary Invasive Adenocarcinoma With Ground-glass Opacity
Status: UNKNOWN
Conditions: Lymph Node Excision
Interventions: PROCEDURE: systematic sampling of the lymph-node|PROCEDURE: lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: cTBS Targeting Cerebellum for Drug-refractory Epilepsy
Status: COMPLETED
Conditions: Drug Refractory Epilepsy
Interventions: DEVICE: cTBS First|DEVICE: Pseudo-stimulation First
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Exploring Diuretics Effective Management in Acute Decompensated Heart Failure, EDEMA Trial
Status: UNKNOWN
Conditions: Acute Decompensated Heart Failure|Diuretics Resistance
Interventions: OTHER: Frusemide IV shots|OTHER: Frusemide IV infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Lu 31-130 in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Zicronapine|DRUG: Zicronapine|DRUG: Zicronapine|DRUG: Zicronapine|DRUG: Zicronapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Intra- and Postoperative Continuous Infusion of Lidocaine on Analgesia in Vascular Anaesthesia
Status: COMPLETED
Conditions: Abdominal Aorta Aneurysm|Abdominal Aorta Atheroma|Surgery|Pain, Postoperative
Interventions: DRUG: lidocaine 10mg/ml|DRUG: Placebo|DRUG: Metamizole|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Collateral Circulation to LAD and Wellens Sign
Status: UNKNOWN
Conditions: Coronary Artery Disease|Acute Myocardial Infarction|Acute Myocardial Infarction of Anterior Wall|Collateral Circulation, Any Site
Interventions: OTHER: Wellens Sign
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bi-Level Positive Airway Ventilation for Acute Chest Syndrome
Status: TERMINATED
Conditions: Sickle Cell Anemia|Acute Chest Syndrome
Interventions: DEVICE: Bi-level positive airway pressure device|DEVICE: Sham CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE