pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intranasal Dexmedetomidine for Procedural Pain Management in Elderly Adults in Palliative Care
Status: TERMINATED
Conditions: Analgesia|Sedation|Anxiolysis
Interventions: DRUG: Opioids|DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Anlotinib in Patients With Radioiodine Refractory Differentiated Thyroid Cancer
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced or Metastatic Radioiodine-refractory Differentiated Thyroid Carcinoma
Interventions: DRUG: Anlotinib Hydrochloride Capsule and Penpulimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIFU Ablation vs Fixed-dose RAI-131 Therapy in Moderate-sized Non-toxic MNG
Status: COMPLETED
Conditions: Non Toxic Multinodular Goiter|High Intensity Focused Ultrasound|RAI
Interventions: DEVICE: Echopulse|RADIATION: Radioactive iodine (Radioidine i131)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Stem Cells for Bronchopulmonary Dysplasia
Status: WITHDRAWN
Conditions: Bronchopulmonary Dysplasia
Interventions: DRUG: transplantation of mesenchymal stem cell|DRUG: no transplantation of mesenchymal stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atomoxetine for Attention Deficit Hyperactivity Disorder in Adolescents With Substance Use Disorder
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Substance Abuse
Interventions: DRUG: Atomoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Effectiveness Study of JUVÉDERM VOLIFT® XC Versus Control for Moderate to Severe Nasolabial Folds
Status: COMPLETED
Conditions: Moderate to Severe Nasolabial Folds
Interventions: DEVICE: JUVEDERM VOLIFT® XC|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Market Registry of AURYON™ Atherectomy Device in Subjects Affected With Infrainguinal Peripheral Artery Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Infrainguinal Peripheral Artery Disease|Peripheral Arterial Disease|PAD
Interventions: DEVICE: AURYON™ System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Upper Extremity Rehabilitation Using Robot and Botulinum Toxin
Status: UNKNOWN
Conditions: Stroke|Spasticity
Interventions: OTHER: Early Inmotion and Botox|OTHER: Botox, then Inmotion|OTHER: Inmotion, then Botox|OTHER: Late Inmotion and Botox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of EAP and Disease-Specific Chemotherapy Regimens in Hematopoietic Stem Cell Mobilization for Lymphoma
Status: RECRUITING
Conditions: Non-Hodgkin's Lymphoma|Hematopoietic Stem Cell Mobilization
Interventions: DRUG: Etoposide|DRUG: Cytarabine|DRUG: PEG-rhG-CSF|DRUG: G-CSF|COMBINATION_PRODUCT: CHOP|COMBINATION_PRODUCT: Hyper-CVAD|COMBINATION_PRODUCT: ID-MTX + Ara-C|COMBINATION_PRODUCT: DA-EPOCH|COMBINATION_PRODUCT: GDP|COMBINATION_PRODUCT: GDPE|COMBINATION_PRODUCT: ICE|COMBINATION_PRODUCT: DICE|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Crossover Trial for the Evaluation of the Possible Effects in the Intestine of Two Different Pharmaceutical Forms of L - Thyroxine in Patients With Primary Acquired Hypothyroidism
Status: UNKNOWN
Conditions: Hypothyroidism
Interventions: DRUG: L-Thyroxine (tablet, per os)|DRUG: L-Thyroxine (oral drops, solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: High Intensity Interval Training and Muscle Adaptations During PR
Status: RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive|Mitochondrial Alteration|Oxygen Deficiency
Interventions: OTHER: Modality of exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of SR 31747A Versus Placebo in Androgen-Independent Non Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasm
Interventions: DRUG: SR31747A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The 90% Effective Dose of Remimazolam for Duodenoscopy Insertion During ERCP With Alfentanil 10µg/kg
Status: UNKNOWN
Conditions: Anesthesia
Interventions: DRUG: Remimazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dual CD33-CLL1-CAR-T Cells in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Fludarabine|DRUG: Cytoxan|BIOLOGICAL: Dual CD33-CLL1 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Amylin in Bone Metabolism
Status: RECRUITING
Conditions: Bone Diseases, Metabolic|Type 1 Diabetes
Interventions: OTHER: Pramlintide|OTHER: Placebo (saline) infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ILLUMENATE EU Randomized Clinical Trial
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Claudication
Interventions: DEVICE: CVI Paclitaxel-coated Percutaneous Transluminal Angioplasty Balloon Catheter|DEVICE: Bare Percutaneous Transluminal Angioplasty Balloon Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of a Hospital Pharmacist's Intervention on FENO (Fractional Exhaled Nitric Oxide) in Asthmatic Patients
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: Pharmacist's intervention|OTHER: Questionnaires for control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Amyloid and Tauopathy PET Imaging in Acute and Chronic Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury|Chronic Traumatic Encephalopathy|Mild Cognitive Impairment
Interventions: DRUG: Amyvid PET Scan|DRUG: T807 PET scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Durvalumab Maintenance After Thoracic Chemoradiotherapy in Frail Small Cell Lung Cancer Patients Whose Disease is Limited to the Thorax
Status: RECRUITING
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of Different Oral Viramune Extended Release Formulations Compared to Viramune® Oral Suspension in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: NVP ER 300 mg (KCR 20%) Medium Release|DRUG: NVP ER 300 mg (KCR 25%) Medium Release|DRUG: NVP ER 300 mg (KCR 30%) Slow Release|DRUG: NVP ER 400 mg (KCR 25%) Medium Release|DRUG: NVP ER 300 mg (KCR 40%) Slow Release|DRUG: NVP ER 300 mg (ECR 20%) Fast Release|DRUG: NVP ER 400 mg (KCR 20%) Medium Release|DRUG: NVP ER 400 mg (KCR 30%) Slow Release|DRUG: NVP ER 400 mg (KCR 40%) Slow Release|DRUG: NVP ER 400 mg (ECR 20%) Fast Release|DRUG: Nevirapine immediate release (IR) 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Pentostatin Plus Cyclophosphamide With Ofatumumab (PCO) in Older Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Pentostatin|DRUG: Cyclophosphamide|DRUG: Ofatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Mesenchymal Stem Cells in the Management of Severe COVID-19 Pneumonia
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: Umbilical cord derived mesenchymal stem cells|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Scleroderma Lung Disease
Status: COMPLETED
Conditions: Lung Diseases|Pulmonary Fibrosis|Systemic Scleroderma|Scleroderma, Systemic
Interventions: DRUG: Cyclophosphamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of the Predictive Value of Fecal Calprotectin for the Outcome of Severe Alcoholic Hepatitis
Status: COMPLETED
Conditions: Severe Alcoholic Hepatitis
Interventions: BIOLOGICAL: fecal calprotectin concentration|BIOLOGICAL: blood collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of ProMetic BioTherapeutics Immune Globulin Intravenous (Human) 10%
Status: COMPLETED
Conditions: Primary Immunodeficiency
Interventions: BIOLOGICAL: Immune Globulin Intravenous|BIOLOGICAL: Prometic's Immune Globulin Intravenous 10%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial in Subjects With Mild to Moderate Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: BIOLOGICAL: B244|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Natrox® Oxygen Wound Therapy on the Healing Rate of Chronic Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer|Surgical Wound
Interventions: DEVICE: Natrox® Oxygen Wound Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety, Tolerance and Anti-tumor Activity of HBM1020 in Subjects With Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: HBM1020
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flare Prevention Study of Canakinumab in Patients With Active Systemic Juvenile Idiopathic Arthritis (SJIA)
Status: COMPLETED
Conditions: Systemic Juvenile Idiopathic Arthritis With Active Flare
Interventions: DRUG: canakinumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Feasibility of the PAINReportIt Guided Relaxation Intervention-Outpatient
Status: COMPLETED
Conditions: Sickle Cell Disease|Stress|Pain
Interventions: BEHAVIORAL: Guided Relaxation video clip|BEHAVIORAL: Sickle Cell Disease Experience Discussion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Micronised Resveratrol as a Treatment for Friedreich Ataxia
Status: COMPLETED
Conditions: Friedreich Ataxia
Interventions: DRUG: Resveratrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interaction Between Levothyroxine and Probiotics in Hypothyroid Patients
Status: COMPLETED
Conditions: Hypothyroidism
Interventions: OTHER: a mixture of highly charged Lactobacilli and Bifidobacteria (VSL#3®)|DRUG: levothyroxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: "Night Vision and Carotenoids"
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DIETARY_SUPPLEMENT: EyePromise Visual Edge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Behavioral Relaxation Approaches for Insomnia in Pregnant Patients
Status: ENROLLING_BY_INVITATION
Conditions: Sleep Initiation and Maintenance Disorders|Pregnancy Related
Interventions: BEHAVIORAL: Assisted Therapy|BEHAVIORAL: Sleep Hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ginsenoside-Rd for Acute Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DRUG: ginsenoside-Rd|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High Definition Transcranial Direct Current Stimulation (HD-tDCS) for Refractory Epilepsy
Status: RECRUITING
Conditions: Transcranial Direct Current Stimulation|EEG|Functional Magnetic Resonance Imaging|Refractory Epilepsy|Transcranial Magnetic Stimulation
Interventions: DEVICE: Active Comparator: Unilateral real High definition transcranial direct current stimulation|DEVICE: Active Comparator: Bilateral real High definition transcranial direct current stimulation|DEVICE: Sham Comparator: Sham High definition transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-dose, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DDO-3055 Tablets in Patients With Anemia of Non-dialysis Chronic Kidney Diseases.
Status: UNKNOWN
Conditions: Anemia Associated Chronic Kidney Disease
Interventions: DRUG: DDO-3055 tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectivity and Safety of Favipiravir Compared to Oseltamivir as Adjuvant Therapy for COVID-19
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: Favipiravir|DRUG: Oseltamivir 75mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stryker Triathlon Total Knee System for Total Knee Arthroplasty Implanted Using Shapematch Cutting Guides:Sub-Study A
Status: COMPLETED
Conditions: Arthroplasties, Replacement, Knee
Interventions: DEVICE: Shapematch Cutting Guides
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Type 2 Diabetes After Gastric Bypass Surgery
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Actrapid insulin+Gloucose|DRUG: Actrapid insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Using Dexmedetomidine to Decreases Emergence Delirium in Pediatric Patients
Status: TERMINATED
Conditions: Otitis Media
Interventions: DRUG: dexmedetomidine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Renal Allograft : Evaluation of Parenchymal Fibrosis by Elastography
Status: UNKNOWN
Conditions: Renal Transplant
Interventions: DEVICE: Magnetic Resonance Elastography, and Supersonic Shear Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ProActIF-01 Trial: Randomized Study of Evaluation of an Individualized Program of Nutrition and Adapted Physical Activity in Frail Patients With Advanced Lung or Digestive Cancers
Status: RECRUITING
Conditions: CANCER
Interventions: OTHER: APA and nutrition intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Longevity of Prefabricated Band and Loop Versus Conventional Band and Loop Space Maintainers
Status: NOT_YET_RECRUITING
Conditions: Premature Tooth Exfoliation
Interventions: DEVICE: Prefabricated band and loop|DEVICE: Conventional Band and loop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Face-to-face, Synchronous and Asynchronous Use of Methods Tele-Assessment
Status: COMPLETED
Conditions: Stroke Patients
Interventions: OTHER: Comparison of Face-to-face, Synchronous and Asynchronous Use of Methods Used for Balance Assessment in Individuals With Chronic Stroke
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: WalkIT Arizona: Walking Interventions Through Texting
Status: COMPLETED
Conditions: Physical Activity|Behavior|Goals
Interventions: BEHAVIORAL: Adaptive Goals|BEHAVIORAL: Static Goals|BEHAVIORAL: Delayed (non-contingent) Incentives|BEHAVIORAL: Immediate Micro-Incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Maintaining Fitness During Neo-adjuvant Chemotherapy for Oesophago-gastric Cancer: a Feasibility Study
Status: UNKNOWN
Conditions: Esophageal Adenocarcinoma|Gastric Adenocarcinoma
Interventions: OTHER: ChemoFit exercise prehabilitation intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study for Evaluation of Immunogenicity and Reactogenicity of Fluarix™ / Influsplit SSW® 2008/2009 in Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluarix™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Continuous Midwife Support on Various Parameters Related to Pregnancy, Childbirth and Postpartum Period
Status: NOT_YET_RECRUITING
Conditions: Pregnant Women|Childbirth|Women's Health
Interventions: OTHER: Continuous midwife support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Test an Approved Product in the Early Treatment of Migraine (0462-065)
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: MK0462, rizatriptan benzoate / Duration of Treatment: 1day|DRUG: Comparator: placebo / Duration of Treatment: 1 day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting the Gut to Improve Seizure Control in CDKL5 Deficiency Disorder (CDD)
Status: RECRUITING
Conditions: CDKL5
Interventions: DIETARY_SUPPLEMENT: alpha-lactalbumin, fructooligosaccharides, inulin|DIETARY_SUPPLEMENT: alpha-lactalbumin, sodium butyrate, fructooligosaccharides, inulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of SP-02L in Relapsed or Refractory Patients With Peripheral T-cell Lymphoma (PTCL)
Status: COMPLETED
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: SP-02L (darinaparsin for injection)|DRUG: SP-02L (darinaparsin for injection)|DRUG: SP-02L (darinaparsin for injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estrogen Deficiency on Cardiovascular Risk
Status: NOT_YET_RECRUITING
Conditions: Postmenopausal Symptoms|Cardiovascular Diseases
Interventions: DRUG: Placebo|DRUG: Estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral Topotecan With Toripalimab for Patients With Endometrial Cancer
Status: NOT_YET_RECRUITING
Conditions: Endometrial Cancer
Interventions: DRUG: Topotecan|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association of Survival With Maintenance Therapy in Patients With Metastatic Breast Cancer After First-line Chemotherapy
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Capecitabine|DRUG: Liposomal doxorubicin|DRUG: Gemcitabine|DRUG: Fulvestrant|DRUG: Anastrozole|DRUG: Letrozole
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of a Multidomain Lifestyle Intervention on Brain Functioning and Its Relation With Immunometabolic Markers in Ageing
Status: COMPLETED
Conditions: Life Style|Risk Reduction|Cognitive Decline|Aging
Interventions: BEHAVIORAL: Multidomain lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Foreskin Graft Tubularized Incised Plate Urethroplasty vs Tubularized Incised Plate for Primary Hypospadias (FGTIP-TIP)
Status: UNKNOWN
Conditions: Hypospadias
Interventions: PROCEDURE: Foreskin Graft-Tubularized Incised Plate|PROCEDURE: Tubularized Incised Plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Domvanalimab and Zimberelimab in Advanced Liver Cancers
Status: RECRUITING
Conditions: Hepatobiliary Cancer|Liver Cancer|Cholangiocarcinoma|Hepatocellular Carcinoma
Interventions: DRUG: Zimberelimab|DRUG: Domvanalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Two Exercise Protocols in the Treatment of Patients With Patellar Tendinopathy
Status: TERMINATED
Conditions: Patellar Tendinopathy
Interventions: OTHER: Eccentric|OTHER: Modified Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Adding Budesonide to Poractant Alfa to Prevent Bronchopulmonary Dysplasia.
Status: UNKNOWN
Conditions: Bronchopulmonary Dysplasia|Infant,Premature|Respiratory Distress Syndrome
Interventions: DRUG: Budesonide|DRUG: Poractant Alfa|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: FM-SRP and Tooth Extraction Improve Type 2 Diabetes Mellitus in Periodontitis
Status: UNKNOWN
Conditions: Periodontitis|Type 2 Diabetes Mellitus
Interventions: PROCEDURE: Surgical Periodontal Treatment|DEVICE: Non Surgical Periodontal Treatment includes scaling root planing with UDS-J Ultrasonic Scaler.|DRUG: Non Surgical Periodontal Treatment includes post operative mouth wash with Listerine® (ethanol 21.6%, methyl salicylate 0.06%, menthol 0.042%, thymol 0.064% and eucalyptol 0.092%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Letrozole, Everolimus and TRC105 in Postmenopausal Women With Hormone-Receptor Positive and Her2 Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Letrozole|DRUG: Everolimus|DRUG: TRC105
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Coronavirus Therapies to Prevent Progression of Coronavirus Disease 2019 (COVID-19) Trial
Status: COMPLETED
Conditions: Coronavirus|Severe Acute Respiratory Syndrome
Interventions: DRUG: Colchicine|DRUG: Interferon-Beta|DRUG: Aspirin|DRUG: Rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Isometric Exercise Training in Participants With Heart Failure With Preserved Ejection Fraction
Status: NOT_YET_RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: OTHER: Isometric exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Transcranial Magnetic Stimulation Used to Both Measure Cortical Excitability and Explore Methamphetamine Cue Craving
Status: COMPLETED
Conditions: Methamphetamine Dependence
Interventions: DEVICE: Transcranial Magnetic Stimulation|DEVICE: Sham Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer
Status: NOT_YET_RECRUITING
Conditions: HPV-Related Cervical Carcinoma|HPV Positive Oropharyngeal Squamous Cell Carcinoma
Interventions: DRUG: Two IM injections Lenti-HPV-07|DRUG: One IM injection Lenti-HPV-07
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults With GD2+ Solid Tumors
Status: COMPLETED
Conditions: Sarcoma|Osteosarcoma|Neuroblastoma|Melanoma
Interventions: BIOLOGICAL: Anti-GD2-CAR engineered T cells|DRUG: AP1903|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Information Received About Fertility and Infertility in Patients Who Have Finished Treatment for Cancer
Status: UNKNOWN
Conditions: Cancer
Interventions: OTHER: questionnaire administration|OTHER: study of socioeconomic and demographic variables|PROCEDURE: assessment of therapy complications|PROCEDURE: fertility assessment and management|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Preoperative Blood Flow Restriction Training in Patients Undergoing ACL Reconstruction
Status: COMPLETED
Conditions: ACL Injury|Sports Physical Therapy
Interventions: DEVICE: Blood Flow Restriction Therapy|DEVICE: Blood Flow Restriction Therapy Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Heart Rate Evaluation and Resuscitation Trial in Preterm Neonates
Status: COMPLETED
Conditions: Neonatal Resuscitation|Infant, Premature
Interventions: OTHER: Electrocardiogram group|OTHER: Pulse oximeter and auscultation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prospective Sibling Oocyte Study of a New Method to Improve Embryo Development in IVF/ICSI Patients
Status: RECRUITING
Conditions: Infertility
Interventions: DEVICE: HyperSperm|DEVICE: Standard Sperm Preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Compound Amino Acid Tablets on Nutritional Status of Patients With Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Amino Acid Deficiency|Malnutrition|Lung Cancer
Interventions: DIETARY_SUPPLEMENT: amino acid tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Video Modeling of Audiological Testing on Pediatric Patient Compliance
Status: COMPLETED
Conditions: Autism
Interventions: BEHAVIORAL: Video Modeling Intervention|BEHAVIORAL: Placebo Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Parenteral Nutrition to Patients With Gastrointestinal Cancer
Status: TERMINATED
Conditions: Gastrointestinal Cancer|Dietary Modification|Cancer Cachexia|Quality of Life|Body Composition, Beneficial
Interventions: DIETARY_SUPPLEMENT: Dietician advise|DIETARY_SUPPLEMENT: Parenteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Satisfaction in Patients Receiving the PegIntron Pen Plus Rebetol for Hepatitis C (Study P04244)(COMPLETED)
Status: COMPLETED
Conditions: Hepatitis C, Chronic|Hepacivirus
Interventions: BIOLOGICAL: Peginterferon alfa-2b (SCH 54031)|DRUG: Ribavirin (SCH 18908)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quantitative Assessment of the Efficacy of Two Irrigation Activation Systems
Status: COMPLETED
Conditions: Periapical Periodontitis|Polymerase Chain Reaction|Enterococcus Faecalis Infection|Irrigation Activation
Interventions: OTHER: XP-endo Finisher to use irrigation activation|OTHER: EndoActivator to use irrigation activation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Rehab for Parkinson's
Status: COMPLETED
Conditions: Parkinson's Disease|Mild Cognitive Impairment
Interventions: BEHAVIORAL: cognitive training|BEHAVIORAL: active control cognitive training|BEHAVIORAL: memory strategy training|BEHAVIORAL: memory strategy training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study for the Evaluation of the Effectiveness of Use of a Poly-L Lactic Acid Injectable Filler for the Aesthetic Treatment of Buttocks Volume Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Buttocks Volume Loss
Interventions: DEVICE: Gana X
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Healthy Subject Study With Z-360 and Placebo
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Z-360|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PGL4001 Efficacy Assessment in Reduction of Symptoms Due to Uterine Leiomyomata
Status: COMPLETED
Conditions: Uterine Fibroids
Interventions: DRUG: PGL4001 5 mg|DRUG: PGL4001 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of IMP 08P1902F0 Relative to Contramal® (100 mg/mL Oral Solution)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tramadol Hydrochloride 5 MG/ML Oral Solution|DRUG: Tramadol Hydrochloride 100 MG/ML Oral Solution (Contramal(r))
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changing to Nonprotease Inhibitor Treatment to Improve Side Effects
Status: COMPLETED
Conditions: HIV Infections|Lipodystrophy
Interventions: DRUG: Abacavir sulfate, Lamivudine and Zidovudine|DRUG: Abacavir sulfate|DRUG: Efavirenz|DRUG: Nevirapine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of mRNA-5671/V941 as Monotherapy and in Combination With Pembrolizumab (V941-001)
Status: COMPLETED
Conditions: Neoplasms|Carcinoma, Non-Small-Cell Lung|Pancreatic Neoplasms|Colorectal Neoplasms
Interventions: BIOLOGICAL: V941|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Diuretic Therapy in Type 1 Cardiorenal Syndrome
Status: RECRUITING
Conditions: Cardiorenal Syndrome Type 1
Interventions: OTHER: Diuretic de/escalation based on ultrasound findings (VExUS Score)|OTHER: Diuretic de/escalation based on clinical findings (CCS Score)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Polihexanide SSIs Measures Bundle (PSMB) During Enhanced Recovery After Major Digestive Surgery
Status: NOT_YET_RECRUITING
Conditions: Surgical Site Infection|Surgical Procedures, Operative
Interventions: COMBINATION_PRODUCT: Polihexanide-based bundle|COMBINATION_PRODUCT: Standard bundle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Infusion for Pain After Herniotomy
Status: UNKNOWN
Conditions: Hernia, Inguinal|Lidocaine|Pain, Postoperative|Chronic Pain
Interventions: DRUG: Lidocaine|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-Intensity Oscillatory Magnetic Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme (GBM) - An Exposure-time Escalation Pilot Trial
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma Multiforme
Interventions: DEVICE: Oncomagnetic device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin Versus Standard of Care Treatment in Pregnant Women With Prediabetes
Status: NOT_YET_RECRUITING
Conditions: Prediabetes; Complicating Pregnancy
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post Coronary Artery Bypass Graft (CABG) Study
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Myocardial Ischemia
Interventions: DRUG: lovastatin|DRUG: cholestyramine|DRUG: warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effects of N-acetylcysteine on Pulmonary Function in High-risk Patients Undergoing Off-pump Coronary Bypass Surgery
Status: COMPLETED
Conditions: Coronary Artery Occlusion
Interventions: DRUG: N-acetylcysteine, saline
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease
Status: RECRUITING
Conditions: Beta-Thalassemia|Thalassemia|Hematologic Diseases|Genetic Diseases, Inborn|Hemoglobinopathies|Sickle Cell Anemia|Sickle Cell Disease
Interventions: BIOLOGICAL: CTX001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis
Status: RECRUITING
Conditions: Colitis, Ulcerative
Interventions: DRUG: Guselkumab Subcutaneous|DRUG: Guselkumab Intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Tarceva in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Lung Cancer|Non-small-cell Lung Carcinoma
Interventions: DRUG: Tarceva (erlotinib HCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of a Photoaging App Versus School-Based Educational Intervention on Adolescents' Knowledge, and Attitudes Towards Tobacco Use
Status: COMPLETED
Conditions: Tobacco Use Cessation|Smoking Cessation|Smoking Prevention
Interventions: OTHER: SmokerFace App from the Education Against Tobacco (EAT) program|OTHER: The use of standardized school-based educational module
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of PEM Treatment of Superficial Axial and Tributary Vein Reflux on Improvement of Wound Healing in VLUs
Status: WITHDRAWN
Conditions: Leg Ulcer|Veins, Varicose|Venous Ulcer|Reflux|Venous Reflux|Venous Leg Ulcer|Varicose Veins|Varicose Ulcer|Varicose Veins Leg
Interventions: DRUG: Polidocanol Endovenous Microfoam (PEM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Families, Children and Teachers Thriving Together
Status: ACTIVE_NOT_RECRUITING
Conditions: Social Anxiety|Emotional Stress
Interventions: BEHAVIORAL: Thrive Professional Learning plus ParentCorps|BEHAVIORAL: Thrive Professional Learning only|BEHAVIORAL: Inspire Professional Learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase II Neoadjuvant ER+/PgR + Arimidex +/- Iressa Study
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Anastrazole|DRUG: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Regeneration of Posterior Cruciate Ligament Injury Using Hypoxic Conditioned Allogenic Adipose Mesenchymal Stem Cell and Condition Medium
Status: UNKNOWN
Conditions: Adypose Mesenchimal Stem Cell|Ligament Rupture|Ligament Derived Conditined Medium
Interventions: BIOLOGICAL: adypose mesenchymal conditioned medium and ligament derived conditioned medium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Airway and/or Pulmonary Vessels Transplantation
Status: COMPLETED
Conditions: Lung Cancer|Tracheal Neoplasm|Tracheal Stenosis
Interventions: PROCEDURE: Airway and/or pulmonary Vessels Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lung Recruitment Maneuvers for Postoperative Atelectasis Prevention After Idiopathic Adolescents' Scoliosis Correction
Status: COMPLETED
Conditions: Postoperative Atelectasis|Lung Recruitment|Scoliosis; Adolescence
Interventions: PROCEDURE: conventional lung recruitment|PROCEDURE: ultrasound- guided lung recruitment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Trial on the Safety of a New Liposomal Adjuvant System, CAF01, When Given With the Tuberculosis Subunit Vaccine Ag85B-ESAT-6 as Two Injections With Two Months Interval to Healthy Adult Volunteers
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: 50 µg Ag85B-ESAT-6 alone|BIOLOGICAL: 50 µg Ag85B-ESAT-6 + 125/25 µg CAF01|BIOLOGICAL: 50 µg Ag85B-ESAT-6 + 313/63 µg CAF01|BIOLOGICAL: 50 µg Ag85B-ESAT-6 + 625/125 µg CAF01
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Intra-Abdominal Fat Extraction Using HydraSolve T2D™ in Obese Subjects With Type 2 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Insulin Resistance
Interventions: DEVICE: HydraSolve T2D™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Pentoxifylline in Human T-lymphotropic Virus Type-1 (HTLV-1) Diseases
Status: COMPLETED
Conditions: HTLV-1|Tropical Spastic Paraparesis|Immune System Diseases|Physical Disability|Pentoxifylline
Interventions: DRUG: Pentoxifylline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Using Spy Elite System in Planning Tissue Advancement Flaps After Ventral Hernia Repair
Status: COMPLETED
Conditions: Ventral Hernia
Interventions: DEVICE: SPY - Unblinded use of SPY Elite|DEVICE: Control - Blinded use of SPY Elite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CD123-Targeted CAR-T Cell Therapy for Relapsed/Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Leukemia|Leukemia, Myeloid|Leukemia, Myeloid, Acute
Interventions: BIOLOGICAL: CD123 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cervical Laminectomy With or Without Lateral Mass Fixation in Cervical Spondylotic Myelopathy
Status: NOT_YET_RECRUITING
Conditions: Degenerative Cervical Myelopathy (DCM)
Interventions: PROCEDURE: laminectomy without lateral mass fixation|PROCEDURE: laminectomy with lateral mass fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Graft Choices in Mediale Patellofemoral Ligament Reconstruction (MPFL)
Status: RECRUITING
Conditions: Patellar Dislocation
Interventions: PROCEDURE: Quadriceps graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oncological Outcomes of Different Patterns of Tumor Recurrence at First Evaluation After Bacillus Calmette-Guérin Induction Therapy for Intermediate and High Risk Non Muscle Invasive Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: induction regimen of intravesical BCG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thalidomide, Dexamethasone, and Clarithromycin in Treating Patients With Multiple Myeloma Previously Treated With Transplant
Status: COMPLETED
Conditions: Refractory Multiple Myeloma|Stage I Multiple Myeloma|Stage II Multiple Myeloma|Stage III Multiple Myeloma
Interventions: DRUG: clarithromycin|DRUG: thalidomide|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of L-PRF on Implant Stability and Marginal Bone Levels.
Status: RECRUITING
Conditions: Dental Implant|Implant Stability|Marginal Bone Levels|L-PRF
Interventions: PROCEDURE: Leukocyte and platelet rich fibrin|PROCEDURE: Standard implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Preoperative Disinfection of Eyes
Status: TERMINATED
Conditions: Eye Infections
Interventions: DRUG: Povidone-Iodine 0.3%|DRUG: Povidone-Iodine 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study To Determine Bioequivalence Between The Commercial Femulen Tablets And A Reformulation Of Femulen Tablets In Healthy Female Subjects
Status: COMPLETED
Conditions: Therapeutic Equivalency
Interventions: DRUG: etynodiol diacetate|DRUG: etynodiol diacetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Add On Treatment for Cognitive Deficits in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: PF 03654746|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial Testing The Effect Of A Multi-Nutrient Fortified Juice
Status: COMPLETED
Conditions: Vitamin D Deficiency|Hypovitaminosis A|Vitamin E Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Vitamin D, Vitamin E, and Vitamin A|DIETARY_SUPPLEMENT: Control, 700 mg Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oxytocin Effect on Attentional Bias Towards Emotional Expression Faces in Individuals With High and Low Autistic Traits: A Functional Magnetic Resonance Imaging (fMRI) Study
Status: UNKNOWN
Conditions: Healthy
Interventions: BEHAVIORAL: screen low autistic subjects|BEHAVIORAL: screen high autistic subjects|DRUG: oxytocin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 2b Study of KBP-5074 in Subjects With Uncontrolled Hypertension and Advanced Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Hypertension
Interventions: DRUG: KBP-5074 0.25 mg tablet|DRUG: KBP-5074 0.5 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT