pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Conservative Treatment and Ultrasound Guided Injection for Treatment Meralgia Paresthetica
Status: COMPLETED
Conditions: Meralgia Paresthetica
Interventions: OTHER: Ultrasound guided injection|OTHER: Transcutaneous Electrical Nerve Stimulation (TENS)|OTHER: Sham Transcutaneous Electrical Nerve Stimulation (TENS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Organic Naked Oat With Whole Germ on Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: organic naked oat with whole germ (ONOG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Asymptomatic COVID-19 Trial
Status: WITHDRAWN
Conditions: SARS-CoV-2 Infection
Interventions: DRUG: Hydroxychloroquine sulfate &Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate Safety and Efficacy of RP-L401-0120 in Subjects With Infantile Malignant Osteopetrosis
Status: TERMINATED
Conditions: Infantile Malignant Osteopetrosis
Interventions: BIOLOGICAL: RP-L401
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomised Placebo-controlled Duloxetine-referenced Study of Efficacy and Safety of 5 mg of Vortioxetine (Lu AA21004) in Acute Treatment of Major Depressive Disorder in Elderly Patients
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Placebo|DRUG: Vortioxetine (Lu AA21004)|DRUG: Duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acoustic Assessment of Nebulized Epinephrine Versus Albuterol for RSV Bronchiolitis- a Double Blind Study
Status: TERMINATED
Conditions: Rsv Bronchiolitis
Interventions: DRUG: nebulized epinephrine and nebulized albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: CLaret Embolic Protection ANd TAVI - Trial
Status: UNKNOWN
Conditions: Frequency of Cerebral Perfusion Defects After TAVI|Size of Cerebral Perfusion Defects After TAVI
Interventions: DEVICE: TAVI (Medtronic CoreValve)|DEVICE: Claret-Filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Predicting Fluid Responsiveness in Mechanically Ventilated Critically Ill Children Using Transthoracic Echocardiography
Status: UNKNOWN
Conditions: Fluid Therapy|Hemodynamics|Hypovolemia|Shock
Interventions: DEVICE: Echocardiographic assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A 48-week Study of the Effect of Dual Therapy (Inhaled Treprostinil and Tadafafil) Versus Monotherapy (Tadalafil).
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: treprostinil inhalations|DRUG: tadalafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of Pembrolizumab, an Immunotherapy Cancer Drug to Olaparib Alone as Therapy for Patients With Pancreatic Cancer That Has Spread With Inherited BRCA Mutations
Status: RECRUITING
Conditions: Metastatic Pancreatic Adenocarcinoma|Pancreatic Adenocarcinoma|Stage IV Pancreatic Cancer AJCC v8
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Olaparib|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Nicorandil on Angina Symptoms in Patients With Coronary Slow Flow
Status: COMPLETED
Conditions: Slow Coronary Flow|Normal, or Near Normal Coronary Angiography|Stable Angina
Interventions: DRUG: Nicorandil|DRUG: Nitroglycerin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Stage I-IIIB Non-Small Cell Lung Cancer After Completion of Radiation Therapy Alone or Combined Radiation Therapy and Chemotherapy
Status: COMPLETED
Conditions: Lung Cancer
Interventions: OTHER: high performance liquid chromatography|OTHER: pharmacological study|PROCEDURE: radionuclide imaging|PROCEDURE: single photon emission computed tomography|RADIATION: radiation therapy|RADIATION: yttrium Y 90 anti-CEA monoclonal antibody cT84.66
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Prophylaxis to Prevent Obesity-Related Induction Complications in Nulliparae at Term
Status: COMPLETED
Conditions: Obesity|Induction of Labor Affected Fetus / Newborn
Interventions: DRUG: Cefazolin|DRUG: Placebo|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Ezogabine (Retigabine) in ALS Subjects
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Ezogabine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examination of Ventavis (Iloprost) Inhalation Behavior Using the I-Neb AAD System in Patients With Pulmonary Arterial Hypertension When Switching the Iloprost Nebulizer Solution for Inhalation From 10 μg/mL (V10) to 20 μg/mL (V20)
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Iloprost,(Ventavis, BAYQ6256)|DEVICE: I-Neb AAD system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Safety, Tolerability and Preliminary Efficacy of EHP-101 in Diffuse Cutaneous Systemic Sclerosis
Status: SUSPENDED
Conditions: Diffuse Cutaneous Systemic Sclerosis
Interventions: DRUG: Patients will be randomized to receive EHP-101 or Placebo|DRUG: Patients will be randomized to receive EHP-101 or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Celecoxib in Colposcopic Directed Biopsy
Status: COMPLETED
Conditions: Colposcopy
Interventions: DRUG: Celecoxib 200mg|PROCEDURE: Colposcopic guided biopsy|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound-assisted Versus Conventional Landmark-guided Paramedian Spinal Anesthesia in Elderly Patients
Status: COMPLETED
Conditions: Anesthesia, Spinal|Ultrasonography
Interventions: PROCEDURE: Ultrasound-assisted paramedian technique spinal anesthesia|PROCEDURE: Landmark-guided paramedian technique spinal anesthesia|DEVICE: Ultrasound|DRUG: 0.5% heavy bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Platform Therapeutic Education in Heart Failure and Coronary Disease
Status: COMPLETED
Conditions: Heart Failure|Acute Coronary Syndrome|Coronary Bypass Graft Stenosis of Native Artery Graft
Interventions: BEHAVIORAL: therapeutic education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigation of Sulindac (HLX-0201) and Gaboxadol (HLX-0206) in Male Fragile X Syndrome Patients Aged 13-40
Status: WITHDRAWN
Conditions: Fragile X Syndrome
Interventions: DRUG: Sulindac (HLX-0201), dose strength 1|DRUG: Sulindac (HLX-0201), dose strength 2|DRUG: Placebo|DRUG: Gaboxadol (HLX-0206)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine If the Volume Used to Dilute BOTOX Cosmetic™ for Injection Affects Its Overall Effect and Duration.
Status: COMPLETED
Conditions: Skin Wrinkling
Interventions: DRUG: Botox Cosmetic™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Switching Nevirapine Immediate Release( IR) Based Regimen to Nevirapine Extended Release (XR) Based Regimen in Human Immunodeficiency Virus One (HIV-1) Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nevirapine XR|DRUG: Nevirapine XR|DRUG: Nevirapine IR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Timing of Follow-up Colonoscopy
Status: ACTIVE_NOT_RECRUITING
Conditions: Colo-rectal Cancer|Colon Polyp|Colonic Polyp|Rectal Polyp|Polyp of Colon|Polyp Rectal|Polyps
Interventions: OTHER: Access to colonoscopy web app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Telephone Contact Between Hospital and General Practitioner About Medication Review for Older Patients
Status: COMPLETED
Conditions: Older Patients|Medication Review|Cross-sectional Communication
Interventions: BEHAVIORAL: Medication review
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intravenous Alcohol Administration Using BrAc Method in Healthy Subjects With and Without a Family History of Alcoholism
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: Ethanol High Dose, Ethanol Low Dose, and Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Mobile App as a Guide to Exercises for Patients With Chronic Stroke
Status: COMPLETED
Conditions: Telerehabilitation|Stroke Sequelae|Therapeutic Adherence and Compliance|Mobile Phone Use|Physical Disability|Neurologic Disorder
Interventions: DEVICE: App-core|OTHER: Conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Instillation of Tranexamic Aacid in Bronchoscopy to Decrease Bleeding During Entobronchial & Transbronchial Biopsiy: a Prospective Double Blind Placebo Controlled Study
Status: UNKNOWN
Conditions: Bronchoscopy Biopsy
Interventions: DRUG: tranexamic acid|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Photobiomodulation on Pain and Healing of the Vertical Releasing Incision After Endodontic Microsurgery
Status: RECRUITING
Conditions: Apical Periodontitis|Endodontically Treated Teeth|Endodontic Disease|Apical Cyst|Apical Granuloma|Periradicular Disease|Previous Endodontic Treatment
Interventions: DEVICE: PBM treatment|DEVICE: PBM sham treatment|DEVICE: EMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of QL1604 Plus Nab-paclitaxel Versus Paclitaxel in Subjects With Advanced Gastric Cancer.
Status: UNKNOWN
Conditions: Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: QL1604|DRUG: Nab-paclitaxel|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of MRSA Bactericidal Gel To Promote Healing and Eliminate MRSA in cSSTI Vancogel(TM)
Status: RECRUITING
Conditions: Bacterial Infections|Wounds
Interventions: DRUG: Vancomycin 1.25-1.50% in a complex gel formulation trademarked Vancogel(R)|DRUG: Placebo, complex gel formulation without Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Peptide Vaccination for Patients With Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Myelodysplastic Syndrome (MDS)
Interventions: DRUG: WT1 and PR1 Peptide Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROlectin M, a Nucleocapsid TErminal GaleCTin Antagonist for COVID-19
Status: UNKNOWN
Conditions: COVID-19|COVID-19 Pandemic|COVID-19 Respiratory Infection|SARS-CoV2 Infection|Cytokine Release Syndrome
Interventions: DRUG: Galactomannan|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of 1018 Immunostimulatory Sequence (ISS) Administered With Irinotecan and Cetuximab to Treat Patients With Previously Treated Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Neoplasms
Interventions: DRUG: 1018 ISS immunostimulatory oligonucleotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Tofacitinib in Hospitalized Participants With COVID-19 Pneumonia Who Are Receiving Standard of Care Therapy
Status: WITHDRAWN
Conditions: COVID-19
Interventions: DRUG: Tofacitinib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mirror Medacta Shoulder System Pivotal Trial
Status: RECRUITING
Conditions: Arthritis Shoulder|Post-traumatic Arthrosis of Other Joints, Upper Arm
Interventions: DEVICE: Mirror Medacta Shoulder System|DEVICE: Medacta Shoulder System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HMS5552 in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: HMS5552|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cytokine Adsorption in Acute-on-chronic Liver Failure
Status: UNKNOWN
Conditions: Acute-On-Chronic Liver Failure|Renal Failure
Interventions: DEVICE: CytoSorb cytokine adsorber|DEVICE: CRRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of Brightening Micro-needle Patch on Facial Solar Lentigines
Status: COMPLETED
Conditions: Solar Lentigines
Interventions: OTHER: AIVÍA, Ultra-Brightening Spot Micro-needle Patch|OTHER: Placebo Micro-needle Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Social Media and Risk Reduction Teaching-Enhanced Reach
Status: RECRUITING
Conditions: Breastfeeding|SUID|SIDS
Interventions: BEHAVIORAL: Prenatal Safe Sleep Mobile Health (mHealth) Messaging|BEHAVIORAL: Prenatal Breastfeeding Mobile Health (mHealth) Messaging|BEHAVIORAL: Postnatal Safe Sleep Mobile Health (mHealth) Messaging|BEHAVIORAL: Postnatal Breastfeeding Mobile Health (mHealth) Messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pomalidomide, Bortezomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Refractory Multiple Myeloma
Interventions: DRUG: pomalidomide|DRUG: bortezomib|DRUG: dexamethasone|OTHER: laboratory biomarker analysis|OTHER: gene expression analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of 2 Oral Formulations of Nintedanib
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nintedanib|DRUG: Nintedanib|DRUG: Nintedanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of PF-06647263 In Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Neoplasms|Triple-Negative Breast Cancer
Interventions: DRUG: PF-06647263|DRUG: PF-06647263
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Desflurane and Anesthesia Recovery Period in Endonasal Endoscopic Pituitary Adenoma Resection
Status: COMPLETED
Conditions: Pituitary Neoplasms
Interventions: DRUG: Desflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of TU-100 in Patients With Functional Constipation
Status: COMPLETED
Conditions: Functional Constipation
Interventions: DRUG: DAIKENCHUTO (TU-100)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Cardiopulmonary Effect of Inhaled Beta-2-agonists on Adult Patients Born With Ventricular Septum Defects.
Status: COMPLETED
Conditions: Ventricular Septal Defect
Interventions: DRUG: Salbutamol|DRUG: Norflouran (Placebo Evohaler(R) )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 3rd Generation GD-2 Chimeric Antigen Receptor and iCaspase Suicide Safety Switch, Neuroblastoma, GRAIN
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroblastoma
Interventions: GENETIC: iC9-GD2 T Cells - frozen|GENETIC: iC9-GD2 T Cells - fresh|DRUG: Cytoxan|DRUG: Fludara|DRUG: Keytruda|GENETIC: iC9-GD2 T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-S16 PET/CT in Healthy Volunteers and Patients With Neurodegenerative Dementia
Status: UNKNOWN
Conditions: Neurodegenerative Dementia
Interventions: DRUG: 18F-S16
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pembrolizumab in Subjects With Incurable Platinum-Refractory Germ Cell Tumors
Status: TERMINATED
Conditions: Germ Cell Neoplasms|Testicular Neoplasms|Non Seminomatous Germ Cell Tumors|Mediastinal Neoplasms|Genital Neoplasms, Male|Genital Neoplasms, Female|Ovarian Neoplasms
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does a Video-based Education Tool Related to Strengthening Result in Different Functional Outcomes Compared to Traditional Physical Therapy Education for Patients?
Status: TERMINATED
Conditions: Patients Receiving Physical Therapy
Interventions: OTHER: Strength education video|OTHER: standard PT care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantitation of Left Ventricular Ejection Fraction Change From Early Exercise Gated Stress/Rest Tc-99m CZT-SPECT MPI
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: OTHER: Single photon emission computed tomography myocardial perfusion imaging|DEVICE: novel cadmium-zinc-telluride (CZT) SPECT cameras
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Interleaved TMS-fMRI for Hippocampal Stimulation: Modeling Dose-Response Relationship in Amnestic Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: Transcranial Magnetic Stimulation|DEVICE: Transcranial Magnetic Stimulation (Sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Probiotic on Seasonal Allergic Rhinitis Symptoms
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Intravenous XMT-1001 in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Small Cell Lung Cancer|Non-small Cell Lung Cancer
Interventions: DRUG: XMT-1001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HGG-TCP (High Grade Glioma - Tumor Concentrations of Protein Kinase Inhibitors)
Status: UNKNOWN
Conditions: Cancer|High-grade Glioma
Interventions: DRUG: Sunitinib|DRUG: vandetanib|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Digitally Assisted Risk Reduction Platform for Youth at High Risk for Suicide
Status: RECRUITING
Conditions: Suicide|Mental Health Disorder|Anhedonia
Interventions: BEHAVIORAL: Vira|BEHAVIORAL: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SB208 for the Treatment of Tinea Pedis
Status: COMPLETED
Conditions: Tinea Pedis
Interventions: DRUG: SB208 2%|DRUG: SB208 4%|DRUG: SB208 16%|DRUG: Vehicle Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Color Stability of Acrylic Denture Teeth in Different Staining Solutions
Status: RECRUITING
Conditions: Color Stability
Interventions: OTHER: Aquafina(water), Coca-cola(coke), Tapal(tea), Shan(turmeric), Krikland(honey)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Safety and Efficacy of PF-06650833, PF-06700841, and PF 06826647 in Adults With Hidradenitis Suppurativa
Status: COMPLETED
Conditions: Acne Inversa
Interventions: DRUG: PF-06650833|DRUG: PF-06700841|DRUG: PF-06826647|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Nursing Technique Applied at the Central Venous Catheter Insertion Site Upon the Incidence of Infection
Status: COMPLETED
Conditions: Surgery|Multiorgan Failure|Haematologic Disease
Interventions: PROCEDURE: CHG technique|PROCEDURE: HMG technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lovastatin for the Treatment of Mildly Active Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Lovastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Ketamine vs Midazolam on Cognitive Function in Elderly in Elective Surgery Three-Months Postoperatively (ketaminvsMDZ)
Status: UNKNOWN
Conditions: Cognitive Dysfunction
Interventions: DRUG: ketamine sedation versus midazolam sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Compare DITEST to Testosterone Undecanoate in Adult Men With Hypogonadism
Status: COMPLETED
Conditions: Male Hypogonadism
Interventions: DRUG: DITEST|DRUG: Testosterone undecanoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI in Predicting Tumor Reponse After Radiofrequency Ablation in Women With Invasive Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: PROCEDURE: Lumpectomy|PROCEDURE: dynamic contrast-enhanced magnetic resonance imaging|PROCEDURE: radiofrequency ablation|RADIATION: gadopentetate dimeglumine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluate Efficacy and Safety of "Kamada-AAT for Inhalation" in Patients With AATD
Status: RECRUITING
Conditions: Alpha 1-Antitrypsin Deficiency
Interventions: DRUG: Alpha 1-Antitrypsin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety and Efficacy of KarXT in Adult Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Xanomeline and Trospium Chloride Capsules|DRUG: Placebo Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Capecitabine Versus Observation Alone in Curatively Resected Stage IB Gastric Cancer((KCSG ST14-05): CATALYSIS
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Frequency of Zoledronic Acid to Prevent Further Bone Loss in Osteoporotic Patients Requiring Androgen Deprivation Therapy for Prostate Cancer
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1 Inhibitor Combined With Azacytidine and Homoharringtonine，Cytarabine, G-CSF for Refractory or Relapsed AML
Status: UNKNOWN
Conditions: Immunotherapy|Refractory Leukemia|Relapsed Adult AML|Acute Myeloid Leukemia
Interventions: DRUG: Visilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Posterior Benign Paroxysmal Positional Vertigo With Mechanical Rotational Chair.
Status: RECRUITING
Conditions: Benign Paroxysmal Positional Vertigo|BPPV
Interventions: PROCEDURE: The Epley Maneuver|PROCEDURE: The 360 Degree Maneuver|DEVICE: Mechanical rotational chair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Autologous Immune Killer Cells in Patients With Late Stage Hepatocellular Carcinoma or Lung Cancer
Status: COMPLETED
Conditions: NSCLC Stage IIIB|NSCLC Stage IV|Hepatocellular Carcinoma by BCLC Stage|Lung Cancer|Liver Cancer
Interventions: BIOLOGICAL: Immune Killer Cells (IKC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefit of Hemostatic Sealant in Preservation of Ovarian Reserve
Status: NOT_YET_RECRUITING
Conditions: Benign Ovarian Cyst|Cystectomy
Interventions: PROCEDURE: Bipolar coagulation|PROCEDURE: Coagulation by FLOSEAL haemostatic agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clopidogrel Optimal Loading Dose Usage to Reduce Recurrent EveNTs/Optimal Antiplatelet Strategy for InterventionS
Status: COMPLETED
Conditions: Acute Coronary Disease|Angina Unstable
Interventions: DRUG: Clopidogrel|DRUG: acetylsalicyclic acid (ASA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesis for Pain Management After Thoracotomy
Status: COMPLETED
Conditions: Postoperative Pain|Analgesia
Interventions: OTHER: Paravertebral Block|OTHER: Serratus Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Different Materials in Pulpotomy of Primary Molars
Status: NOT_YET_RECRUITING
Conditions: Pulp Disease, Dental
Interventions: PROCEDURE: mineral trioxide aggregate pulpotomy|PROCEDURE: Dehydrated amniotic membrane pulpotomy|PROCEDURE: Hyaluronic acid pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Different Methods to Minimize Blood Loss During Laparoscopic Myomectomy; A Randomized Controlled Clinical Trial
Status: RECRUITING
Conditions: Different Methods to Minimize Blood Loss During Laparoscopic Myomectomy
Interventions: PROCEDURE: Laparoscopic myomectomy with intramyometrial injection of diluted epinephrine|PROCEDURE: traditional laparoscopic myomectomy|PROCEDURE: laparoscopic myomectomy with temporary bilateral uterine artery occlusion|DRUG: injection of epinephrine 1mg diluted in 200mg of NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intranasal Mometasone in Children With Obstructive Sleep Apnea Due to Adenotonsillar Hypertrophy
Status: WITHDRAWN
Conditions: Obstructive Sleep Apnea (Mild, Moderate, Severe) as Per Polysomnography
Interventions: DRUG: Mometasone furoate nasal spray|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Preferences and Product Accessibility in Oral Nutritional Supplements in Participants With Breast, Colorectal, Upper Gastrointestinal, or Prostate Cancer
Status: WITHDRAWN
Conditions: Breast Carcinoma|Cholangiocarcinoma|Colorectal Carcinoma|Gastric Carcinoma|Malignant Digestive System Neoplasm|Pancreatic Carcinoma|Prostate Carcinoma
Interventions: OTHER: Interview|OTHER: Survey Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: RCT Study to Validate niPGT-A Clinical Benefit.
Status: RECRUITING
Conditions: Aneuploidy|Chromosome Abnormality|Infertility
Interventions: DIAGNOSTIC_TEST: niPGT-A|OTHER: Morphology criteria
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Butyphthalide on Cognitive Level Change After Cerebral Vascular Event-a Randomized Control Trial (Be-CLEVER)
Status: RECRUITING
Conditions: Stroke|Post-stroke Cognitive Impairment (PSCI)
Interventions: DRUG: dl-3-butylphthalide|DRUG: dl-3-butylphthalide placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alternate Dosing Strategies for Beta-hydroxy-beta-methylbutyrate (HMB) Supplementation: Effect on Plasma HMB Responses
Status: COMPLETED
Conditions: Focus of the Study is to Examine Plasma HMB Levels After Oral HMB Supplementation
Interventions: DIETARY_SUPPLEMENT: CaHMB capsule|DIETARY_SUPPLEMENT: HMB free acid gelcap|DIETARY_SUPPLEMENT: HMB free acid mixed in water|DIETARY_SUPPLEMENT: CaHMB in water|DIETARY_SUPPLEMENT: HMB free acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Aspirin Prophylaxis for Venous Thromboembolism in Glioblastoma
Status: TERMINATED
Conditions: Glioblastoma
Interventions: DRUG: Aspirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Placebo-Controlled Dose Titration Study to Evaluate the Efficacy and Safety of Sandostatin (SMS 201-995) in the Treatment of Patients With Acquired Immunodeficiency Related Diarrhea
Status: COMPLETED
Conditions: Diarrhea|HIV Infections
Interventions: DRUG: Octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 2 Secukinumab Regimens in 90kg or More Weight Group With Moderate/Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Moderate to Severe Chronic Plaque-type Psoriasis
Interventions: DRUG: secukinumab 150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety Study of Prolonged-Release Fampridine in Participants With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: fampridine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Food Effect Study Of AG-013736 In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AG-013736|DRUG: AG-013736|DRUG: AG-013736|DRUG: AG-013736|DRUG: AG-013736|DRUG: AG-013736
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Step Count Monitoring as a Measure of Physical Activity in Patients With Newly Diagnosed Glioma Undergoing Radiation Therapy
Status: RECRUITING
Conditions: Glioma|Radiation Therapy Patient
Interventions: DEVICE: FitBit|DEVICE: Pedometer|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of SINOMED SR for Endovascular Treatment of Acute Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke, Acute|Brain Diseases|Cerebrovascular Disorders
Interventions: DEVICE: Intracranial thrombectomy stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of SCRT Versus TNT in Older Patients With Locally Advanced Rectal Cancer
Status: RECRUITING
Conditions: Locally Advanced Rectal Cancer|Older People
Interventions: RADIATION: Short course radiotherapy|DRUG: Adjuvant chemotherapy (optional)|PROCEDURE: Total mesorectal excision|COMBINATION_PRODUCT: Total neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Magnetically Enhanced Diffusion for Acute Ischaemic Stroke (MEDIS) Trial
Status: SUSPENDED
Conditions: Stroke, Acute|Stroke, Ischemic|Infarction, Middle Cerebral Artery|Strokes Thrombotic|Neurologic Disorder|Cerebrovascular Disorders|Intracranial Embolism and Thrombosis
Interventions: DEVICE: Magnetically Enhanced Diffusion (MED)|DEVICE: MED Workstation Magnet Sham Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Placebo-controlled Efficacy and Safety Study of GSK3511294 (Depemokimab) in Participants With Severe Asthma With an Eosinophilic Phenotype
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: GSK3511294 (Depemokimab)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Danirixin for Disease Progression in Chronic Obstructive Pulmonary Disease (COPD)
Status: TERMINATED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Danirixin 35 mg tablets|DRUG: Placebo|DEVICE: Metered dose inhaler (MDI) sensor device|DRUG: Rescue medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chairside Time and Bond Failure of Non Custom Versus Custom Base Orthodontic Attachments During Indirect Bonding
Status: UNKNOWN
Conditions: Orthodontic Appliance Complication
Interventions: DEVICE: non custom base attachment|DEVICE: custom base attachment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Aflibercept as Mono-therapy in Treat and Extend Regimen for DME Patients in Taiwan
Status: COMPLETED
Conditions: Center-involved Diabetic Macular Edema
Interventions: DRUG: Aflibercept Injection [Eylea]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Toripalimab Plus Sorafenib in Patients With Advanced-Stage Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Toripalimab|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Pharmacokinetic Profile of BMS-986165 Tablets
Status: COMPLETED
Conditions: Lupus
Interventions: DRUG: BMS-986165-01|DRUG: BMS-986165 Tablet|DRUG: Famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Ranging Trial of Safety & Immunogenicity of an Oral Adenoviral-Vector Based RSV Vaccine (VXA-RSV-f)
Status: COMPLETED
Conditions: Respiratory Syncytial Virus (RSV)
Interventions: BIOLOGICAL: VXA-RSV-f Tablets (high dose)|OTHER: VXA Placebo Tablets|BIOLOGICAL: VXA-RSV-f Tablets (low dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Thalidomide for Decreasing Collagen Biosynthesis in People With Progressive Systemic Sclerosis
Status: TERMINATED
Conditions: Scleroderma, Systemic
Interventions: DRUG: Thalidomide|DRUG: Placebo thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Blood Glucose Meter Systems
Status: COMPLETED
Conditions: Diabetes
Interventions: DEVICE: Contour® PLUS BGMS|DEVICE: OneTouch® SelectSimple™ BGMS|DEVICE: Accu-Chek® Performa BGMS|DEVICE: Accu-Chek® Active BGMS|DEVICE: Freestyle Freedom® BGMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trifluridine/ Tipiracil Plus Panitumumab Versus Trifluridine/ Tipiracil Plus Bevacizumab as First-line Treatment of Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: BIOLOGICAL: Panitumumab 20 milligram/ML|BIOLOGICAL: Bevacizumab|DRUG: Trifluridine/Tipiracil Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Traumeel for Post-Tonsillectomy Pain
Status: UNKNOWN
Conditions: Post-Tonsillectomy
Interventions: DRUG: Traumeel S|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Montelukast Back to School Asthma Study (0476-340)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: montelukast|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Nelfinavir and Chemoradiation for Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Neoplasms
Interventions: DRUG: Nelfinavir|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of High-dose Liposomal Amphotericin B for Disseminated Histoplasmosis in AIDS
Status: NOT_YET_RECRUITING
Conditions: Disseminated Histoplasma Capsulatum Infection|AIDS and Infections|Immunosuppression|Fungal Infection
Interventions: DRUG: Single high dose of liposomal amphotericin B|DRUG: L-AmB standard dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pigmented Rice on Reducing Cardiometabolic Risk Factors Among Filipino Adults
Status: ENROLLING_BY_INVITATION
Conditions: Dyslipidemias|Overweight or Obesity|Hyperglycaemia (Non Diabetic)
Interventions: OTHER: Pigmented rice|OTHER: White Rice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiation Therapy (XRT) and ZD6474 in Non-Small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: ZD6474 (ZACTIMA)|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Folates in the Care of the Male Infertility
Status: COMPLETED
Conditions: Male Infertility
Interventions: DRUG: Folic acid|DRUG: placebo of folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Artesunate Study in Severe Malaria
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Artesunate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Combination of Metronomic Oral Vinorelbine and Sorafenib in Patients With Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: oral vinorelbine|DRUG: sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SGN-B6A in Advanced Solid Tumors
Status: RECRUITING
Conditions: Carcinoma, Non-Small Cell Lung|Squamous Cell Carcinoma of Head and Neck|HER2 Negative Breast Neoplasms|Esophageal Squamous Cell Carcinoma|Esophageal Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma|Ovarian Neoplasms|Cutaneous Squamous Cell Cancer|Exocrine Pancreatic Adenocarcinoma|Urinary Bladder Neoplasms|Uterine Cervical Neoplasms|Stomach Neoplasms
Interventions: DRUG: sigvotatug vedotin|DRUG: pembrolizumab|DRUG: cisplatin|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botox Vs Spinal Cord Stimulation in the Treatment of Refractory Migraine Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Migraine
Interventions: COMBINATION_PRODUCT: SCS|COMBINATION_PRODUCT: SCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pomegranate Extract Intake on Body Composition and Blood Pressure.
Status: UNKNOWN
Conditions: Obesity|Diabetes|Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Pomegranate extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Biofeedback Training, Efficacy Evaluation of Fibromyalgia Treatment, a Pilot Study
Status: COMPLETED
Conditions: Biofeedback, Psychology
Interventions: DEVICE: Biofeedback training treatment in Fibromyalgia, a pilot study|OTHER: Control (treatment as usual)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FFI and PR Could Improve Bowel Cleansing.
Status: COMPLETED
Conditions: Bowel Preparation
Interventions: DRUG: PEG-FFI|DRUG: PEG-nonFFI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of REcycled CartiLage Auto/Allo IMplantation to Treat and Repair Focal Hip Cartilage Defects
Status: RECRUITING
Conditions: Cartilage Defect
Interventions: COMBINATION_PRODUCT: Autologous Chondrocytes in their Pericellular Matrix (Chondrons) Coimplanted with Allogeneic Adipose-Derived Mesenchymal Stromal Cells (AMSCs) in a Fibrin Glue Carrier
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of a New Surgical Smoke Clearing Technology in Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Focus: Surgical Smoke During Laparoscopic Surgery
Interventions: DEVICE: Innervision Surgical Smoke Removal System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE