pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Assessing the Effects of HbA1c Reduction on Alleviating Nonspecific Back Pain
Status: COMPLETED
Conditions: Back Pain Lower Back Chronic|Back Pain|Pre Diabetes|Diabetes|Back Pain, Low
Interventions: DIETARY_SUPPLEMENT: Ghazwan program|DRUG: Standard management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Breathing Exercises and Postural Exercises in Young Adults With Asthma.
Status: NOT_YET_RECRUITING
Conditions: Asthma
Interventions: OTHER: Breathing Retraining Program|OTHER: Postural Exerises Program (Stretching and Strengthening Exercises)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Safety and Efficacy of ALLO-ASC-SHEET in Subjects With Dystrophic Epidermolysis Bullosa
Status: RECRUITING
Conditions: Dystrophic Epidermolysis Bullosa
Interventions: BIOLOGICAL: ALLO-ASC-SHEET|OTHER: Vehicle Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for the Disrupted Interpersonal Interaction Among Gaming Disorder Individuals and Treatment
Status: RECRUITING
Conditions: Gaming Disorder
Interventions: DEVICE: tACS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Third, Intensive Care Bundle With Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial
Status: COMPLETED
Conditions: Cerebral Hemorrhage|Stroke|Hypertension|Diabetes|Anticoagulant-induced Bleeding|Cerebral Vascular Disorder|Brain Disorder|Hemorrhage|Intracranial Hemorrhages|Cardiovascular Diseases|Central Nervous System Diseases
Interventions: OTHER: Care bundle of active management|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy for Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Combination of pimecrolimus and fluticasone|DRUG: pimecrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Lozenges Containing Probiotic Lactobacilli on Enamel Demineralization Assed by QLF
Status: COMPLETED
Conditions: Caries Dentalis
Interventions: BIOLOGICAL: L. retueri|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Study of the ICON™ CPAP Series With and Without SensAwake™
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: SensAwake On|DEVICE: SensAwake Off
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ocular Massage on the Management of Elevated Intraocular Pressure After Acute Angle Closure
Status: COMPLETED
Conditions: Intraocular Pressure
Interventions: OTHER: ocular massage|DEVICE: LenstarLS900|DEVICE: Goldmann tonometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subclinical Primary Aldosteronism in Diabetes At-Risk for Kidney Disease
Status: RECRUITING
Conditions: Type 2 Diabetes|Chronic Kidney Diseases
Interventions: DIAGNOSTIC_TEST: Oral sodium suppression test|DIAGNOSTIC_TEST: Saline suppression test|DIAGNOSTIC_TEST: Captopril suppression test|DIAGNOSTIC_TEST: Dexamethasone suppression test|DIAGNOSTIC_TEST: Cosyntropin stimulation test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long-term Safety of Linaclotide in Pediatric Participants With FC or IBS-C
Status: ACTIVE_NOT_RECRUITING
Conditions: Irritable Bowel Syndrome With Constipation|Functional Constipation
Interventions: DRUG: Irritable Bowel Syndrome with Constipation (IBS-C) participants (LIN-MD-63 completers)|DRUG: Functional Constipation (FC) participants (LIN-MD-62 and LIN-MD-64 completers)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: GFF MDI (PT003)|DRUG: FF MDI (PT005)|DRUG: GP MDI (PT001)|DRUG: Placebo MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Combination Tivozanib and Nivolumab in Advanced Non-Clear Cell Renal Cell Carcinoma
Status: RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Tivozanib|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Metformin on Morbidity and Mortality in Elderly Patients
Status: NOT_YET_RECRUITING
Conditions: Burns
Interventions: DRUG: Metformin|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glutamine Popsicles in Bone Marrow Transplant (BMT)/Hematopoietic Stem Cell Transplant (HSCT) Patients
Status: COMPLETED
Conditions: Bone Marrow Transplantation|Hematopoietic Stem Cell Transplantion
Interventions: DRUG: nutritional supplement|DRUG: glutamine popsicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effect of Vitamin A Supplementation on Immune Responses in Human Neonates
Status: UNKNOWN
Conditions: Vitamin A Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin A (retinyl palmitate).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Phase II Clinical Trial of Fentanyl Transdermal Matrix Patch, in the Management of Cancer Pain- Assessment of Effectiveness, Safety and Pharmacokinetics -
Status: COMPLETED
Conditions: Pain, Intractable
Interventions: DRUG: fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Fiber Rye Foods for Body Weight and Body Fat Reduction
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: OTHER: Cereal products based on rye|OTHER: Cereal products based on wheat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Understanding the Pathogenesis and Treatment of Childhood Onset Dermatomyositis
Status: TERMINATED
Conditions: Dermatomyositis
Interventions: DRUG: Prednisone|DRUG: Methotrexate|DRUG: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study to Evaluate Dabigatran Etexilate in Elderly Subjects
Status: RECRUITING
Conditions: Nonvalvular Atrial Fibrillation|Health, Subjective
Interventions: DRUG: Dabigatran etexilate capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-Acebilustat (CTX-4430)
Status: COMPLETED
Conditions: Heathy Volunteers
Interventions: DRUG: [14C]-acebilustat solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Protein Extrusion and Postprandial Amino Acid Handling
Status: COMPLETED
Conditions: Postprandial Plasma Amino Acid Availability
Interventions: DIETARY_SUPPLEMENT: Dry protein blend ingestion|DIETARY_SUPPLEMENT: Extruded protein blend ingestion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Utilizing Novel Information Technology to Promote Exercise and Well-Being in Adolescents and Young Adults With Cancer
Status: COMPLETED
Conditions: Adolescent|Young Adult|Cancer|Physical Activity|Psychological Distress|Social Isolation
Interventions: BEHAVIORAL: Physical Activity Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Value of Narrow Band Imaging (NBI) Endoscopy in the Early Diagnosis of Laryngeal Cancer and Precancerous Lesions
Status: COMPLETED
Conditions: Chronic Inflammation of Hypopharynx|Hoarseness|Macroscopic Laryngeal Lesions|Histological Confirmation of Dysplasia|Carcinoma in Situ|Invasive Carcinoma of Larynx|Invasive Carcinoma of Hypo Pharynx|Recurrent Respiratory Papillomatosis
Interventions: DEVICE: NBI endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Improving Quality of Care in Child Mental Health Service Settings
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder|Technology|Child Abuse
Interventions: BEHAVIORAL: TFCBT|BEHAVIORAL: eTFCBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab, Carboplatin and Cabazitaxel in Aggressive Metastatic Castration Resistant Prostate Cancer (PEAPOD_FOS)
Status: RECRUITING
Conditions: Prostate Cancer Metastatic
Interventions: DRUG: Pembrolizumab|DRUG: Carboplatin|DRUG: Cabazitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Study of DS-1971a
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DS-1971a|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Detection of High Grade Prostate Cancer With Subharmonic Ultrasound Imaging, A Pilot Study
Status: COMPLETED
Conditions: Prostatic Neoplasm
Interventions: DRUG: Perflutren Lipid Microsphere Intravenous Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Ocular Therapeutix) (Axitinib Implant) in Subjects With Neovascular Age-Related Macular Degeneration
Status: RECRUITING
Conditions: Neovascular Age-Related Macular Degeneration
Interventions: DRUG: OTX-TKI (axitinib implant)|DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Locally Delivered Metformin & Rosuvastatin for Treatment of Intrabony Defects in Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Placebos|DRUG: Rosuvastatin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Can Fentanyl Lead to Opioid-induced Hyperalgesia in Healthy Volunteers?
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Evaluating AMD3100 for Transplantation of Sibling Donor Stem Cells in Patients With Hematological Malignancies
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute|Leukemia, Myelogenous, Chronic|Leukemia, Lymphoblastic, Acute|Lymphocytic Leukemia, Chronic|Myelodysplastic Syndromes|Multiple Myeloma|Lymphoma, Non-Hodgkin|Hodgkin Disease
Interventions: DRUG: AMD3100|PROCEDURE: Stem Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bowen's Technique and Muscle Energy Technique on Hamstrings Tightness
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Bowen's Technique|OTHER: Muscle Energy Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Clinician Research Tool
Status: COMPLETED
Conditions: Elevated Risk of Cardiovascular Disease|Tobacco Dependence
Interventions: OTHER: Virtual Clinician Research Tool (VCRT)|OTHER: No VCRT, only physician counseling at visits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: intErnet-based iNterventions FOR Cardiac arrEst suRvivors
Status: RECRUITING
Conditions: Cognitive Impairment|Depression, Anxiety|Cardiac Arrest|Quality of Life|Social Functioning|Sexual Dysfunction
Interventions: BEHAVIORAL: Lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pacing to Maintain Physiologic Ventricular Activation
Status: RECRUITING
Conditions: Pacemaker DDD|His Bundle Pacing|LBB Area Pacing|Pacing-Induced Cardiomyopathy|Left Bundle-Branch Block|ICD
Interventions: DEVICE: cardiac implantable electronic device (CIED) implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Non-invasive Respiratory Support in Preterm Infants
Status: RECRUITING
Conditions: Preterm Infant|Respiratory Insufficiency Syndrome of Newborn|Bronchopulmonary Dysplasia
Interventions: OTHER: Non-invasive respiratory support mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Supplemental Synchronous and Asynchronous Telehealth to Improve Glycemic Control for Pediatric Patients With Type 1 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: BEHAVIORAL: Supplemental video visits|BEHAVIORAL: Standard of Care|BEHAVIORAL: Supplemental remote monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sedation Techniques for Outpatient Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: Propofol 10 MG/ML Injection|DRUG: Midazolam injection|DRUG: Pethidine Hydrochloride 50 Mg/mL Solution for Injection|DEVICE: target controlled infusion pump|DEVICE: patient-controlled sedation pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SA4Ag Safety, Tolerability, and Immunogenicity Study in Japanese Adults
Status: COMPLETED
Conditions: Staphylococcal Infections
Interventions: BIOLOGICAL: Staphylococcus aureus 4-antigen vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Xenon-enhanced Ventilation CT-guided Radiotherapy for Lung Cancer Treatment
Status: RECRUITING
Conditions: Lung Cancer|Radiation Therapy Complication
Interventions: RADIATION: Xenon-enhanced Ventilation CT-guided Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Icodextrin Solution on Preservation of Residual Renal Function in Patients on Peritoneal Dialysis
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DRUG: Icodextrin PD solution|DRUG: glucose solutions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Nuvigil or Placebo in Newly Diagnosed Malignant Glioma
Status: TERMINATED
Conditions: Malignant Glioma
Interventions: DRUG: Nuvigil®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Influence of Telmisartan and Lacidipine, Combined or Alone, on QT Interval in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Telmisartan high|DRUG: Telmisartan low|DRUG: Lacidipine high|DRUG: Lacidipine low|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of First Line Treatment With Tarceva (Erlotinib) in Combination With Gemcitabine in Patients With Unresectable Advanced and/or Metastatic Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer Metastatic
Interventions: DRUG: Erlotinib|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-HER2 Therapy + Fulvestrant/Capecitabine in Women With HR+, HER2+, Non-visceral Metastases Stage IV Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: HER2-positive Breast Cancer
Interventions: DRUG: Pertuzumab|DRUG: Trastuzumab|DRUG: Fulvestrant|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cannabis/Alcohol on Driving Performance and Field Sobriety Tests
Status: WITHDRAWN
Conditions: Driving Impaired|Alcohol Intoxication|Driving Under the Influence|Cannabis Intoxication
Interventions: DRUG: Cannabis|DRUG: Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Quality of Life in Patients With Non-adipocyte Soft Tissue Sarcoma Under Palliative Chemotherapy or Pazopanib
Status: TERMINATED
Conditions: Soft Tissue Sarcoma Adult
Interventions: DRUG: pazopanib or guideline conform chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selumetinib and Paclitaxel as Second-Line Treatment in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Stage IIIB Non-Small Cell Lung Cancer AJCC v7|Stage IV Non-Small Cell Lung Cancer AJCC v7
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|OTHER: Pharmacological Study|DRUG: Selumetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab, 5-FU and Radiation as Neoadjuvant Therapy for Patients With Locally Advanced Rectal Cancer
Status: TERMINATED
Conditions: Rectal Cancer
Interventions: DRUG: Cetuximab|DRUG: 5-Fluorouracil|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Novel CCH Protocol for PD Among Prior Non-responders
Status: RECRUITING
Conditions: Peyronie's Disease
Interventions: DRUG: CCH administration|DRUG: Control - Crossover to CCH|DEVICE: RestoreX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Positive Emotions Program for Schizophrenia (PEPS)
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Positive Emotions Program for Schizophrenia|BEHAVIORAL: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Open-Label Trial to Assess the Absorption, Metabolism, and Excretion of (14C)-OPC-61815 in Healthy Male Japanese Subjects
Status: COMPLETED
Conditions: Healthy Adult Male
Interventions: DRUG: (14C)-OPC-61815
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Ibuprofen D, Oral Suspension, 200 mg/5ml and Nurofen®, Oral Suspension 100 mg/5 ml in Healthy Volunteers Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ibuprofen D|DRUG: Nurofen® for Children
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lapatinib and Vinorelbine in Treating Women With HER2-Overexpressing Locally Advanced or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Lapatinib|DRUG: vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of 1 and 2 Doses of GlaxoSmithKline (GSK) Biologicals' Meningococcal Vaccine MenACWY-TT (GSK134612) in Toddlers, Persistence up to 5 Years After Vaccination and Co-administration With Pfizer's Prevenar 13™Vaccine
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Meningococcal vaccine GSK134612|BIOLOGICAL: Prevenar 13™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Methadone and Quality of Postoperative Recovery
Status: RECRUITING
Conditions: Quality of Recovery Scores
Interventions: DRUG: Methadone|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of TBS-2 Testosterone Gel in Women With Acquired Female Orgasmic Disorder
Status: COMPLETED
Conditions: Female Orgasmic Disorder
Interventions: DRUG: Placebo|DRUG: Low dose TBS-2|DRUG: Medium dose TBS-2|DRUG: High dose TBS-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Continuous Non-invasive Haemodynamic Monitoring on the Ward
Status: UNKNOWN
Conditions: Surgical Procedures, Operative|Hemodynamic Instability|Blood Pressure Disorders
Interventions: DEVICE: LIDCO CNAP device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Monocentric Study and Prognostic of Treatments Endodontics of Teeth With Periapical Pathology Realized CSERD (Nantes University Hospital)
Status: COMPLETED
Conditions: Dental Pulp Disorder
Interventions: OTHER: Endodontic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Extended Depth of Focus After Bilateral Implantation of Hydrophobic IOLs
Status: COMPLETED
Conditions: Cataract Senile
Interventions: DEVICE: Implantation of LuxSmart hydrophobic IOLs (Bausch + Lomb) in both eyes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perineal Preparation for Pregnant Ladies.
Status: COMPLETED
Conditions: Delivery; Trauma|Pelvic Floor; Perineal Rupture, Obstetric|Pelvic Floor Muscle Weakness
Interventions: OTHER: 3 program|OTHER: one program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Population-based, Multicenter Cohort Study of Combined Screening for Gastrointestinal Tumors
Status: RECRUITING
Conditions: Digestive Disease
Interventions: OTHER: Gastroenteroscopy；Risk factor investigation; FIT-HP;RNF180 and SEPTIN9 gene methylation test|OTHER: Risk factor investigation;|OTHER: Gastroenteroscopy；Risk factor investigation; FIT-HP;RNF180 and SEPTIN9 gene methylation test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Systemic Lupus Erythematosus With Pooled Allogenic Mesenchymal Stem Cells
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Pooled mesenchymal stem cell|OTHER: Standard treatment according to the Clinical protocols
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Agro-ecological Farming Systems on Human Health
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammatory Response
Interventions: OTHER: 44-Day Diet Conventionally Sourced - YELLOW Diet|OTHER: 44-Day Diet Agro-Ecologically Sourced - GREEN Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Percutaneous Coronary Angioplasty Compared With Exercise Training in Symptomatic Coronary Artery Disease
Status: UNKNOWN
Conditions: CAD|Stable Angina Pectoris
Interventions: DEVICE: PTCA and Stent Implantation|BEHAVIORAL: Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GISSOC II: Sirolimus Eluting Stent Versus Bare Metal Stent in Chronic Total Coronary Occlusions
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Coronary placement of bare metal stent vs. drug eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Sequential Neoadjuvant Treatment Including Chemotherapy and Accelerated Radiation Focused to the Tumor Bed vs Neoadjuvant Chemotherapy Alone
Status: RECRUITING
Conditions: Radiation Therapy, Breast Cancer, Sequential Partial Breast Irradiation|Intermediate and High-risk Luminal and Triple Negative Breast Cancer
Interventions: RADIATION: Accelerated partial breast irradiation|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effects of the Gastrolith, in Osteoporotic Patients Suffering From Recent Skeletal Pain Caused by Vertebral Fractures
Status: WITHDRAWN
Conditions: Osteoporosis
Interventions: DIETARY_SUPPLEMENT: Gastrolith|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Molecular Pharmacodynamic Dose-titration Trial of Conjugated Linoleic Acid (CLA; Clarinol®) in Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumors
Interventions: DIETARY_SUPPLEMENT: Conjugated Linoleic Acid|DRUG: Conjugated Linoleic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating the Effect of a Mobile Audio Companion (Elly) to Reduce Anxiety in Cancer Patients
Status: COMPLETED
Conditions: Cancer|Cancer Metastatic|Neoplasms|Breast Cancer|Lung Cancer|Glioblastoma|Prostate Cancer|Gynecologic Cancer|Colorectal Cancer|Sarcoma|Kidney Cancer|Bladder Cancer|Lymphoma|Leukemia|Head and Neck Cancer|Pancreas Cancer|Multiple Myeloma|Anxiety|Social Isolation|Stress|Loneliness|Melanoma|Uterine Cancer
Interventions: BEHAVIORAL: Elly Mobile Phone Application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rg3 in Combination With TACE in Hepatocellular Carcinoma Patients With High Expression of Notch1
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|TACE|Notch1|Rg3
Interventions: PROCEDURE: TACE|DRUG: Rg3|OTHER: TACE + Rg3|PROCEDURE: protective therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Training for Urinary Leakage Improvement After Pregnancy
Status: NOT_YET_RECRUITING
Conditions: Urinary Incontinence|Delivery Complication
Interventions: OTHER: Interventionist-guided training|DEVICE: Home pelvic floor exercises guided by the leva® device|OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Tunnel Placements on Clinical and MRI Findings Two Years After ACL Reconstruction With DB Technique
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Rupture
Interventions: PROCEDURE: Double-bundle ACL reconstruction|DEVICE: Magnetic resonance imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Changes in Liver Function After Stereotactic Body Radiation Therapy Measured by PET/CT
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Cholangiocarcinoma|Metastases|Stereotactic Body Radiotherapy
Interventions: OTHER: Measuring liver function by PET/CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: IMPACT Study: IMProve Pregnancy in APS With Certolizumab Therapy
Status: RECRUITING
Conditions: High Risk Pregnancy|Pregnancy Complications|Antiphospholipid Syndrome in Pregnancy|Lupus Anticoagulant Disorder
Interventions: DRUG: Certolizumab Pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intravenous Versus Peribulbar Dexmedetomidine for Strabismus Surgery in Adults
Status: COMPLETED
Conditions: Squint
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Individual Differences in the Response to Drugs
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: THC|DRUG: AMP|DRUG: ALC|DRUG: Placebo capsules|DRUG: Placebo beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fluzoparib Combined With Dalpiciclib for Platinum Resistant Recurrent Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Fluzoparib|DRUG: Dalpiciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Weekly Carfilzomib in Combination With Dexamethasone for Progressive Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Security of the Dose Reduction of Ritonavir in HIV-Infected Patients in Treatment With Tipranavir/Ritonavir 500/200 mg Every 12 Hours
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: tipranavir/ritonavir (dose reduction)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GAUSS: A Study of Obinutuzumab (RO5072759) in Patients With Indolent Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: obinutuzumab (RO5072759)|DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fludarabine Phosphate, Radiation Therapy, and Rituximab in Treating Patients Who Are Undergoing Donor Stem Cell Transplant Followed by Rituximab for High-Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Prolymphocytic Leukemia|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Stage III Chronic Lymphocytic Leukemia|Stage III Small Lymphocytic Lymphoma|Stage IV Chronic Lymphocytic Leukemia|Stage IV Small Lymphocytic Lymphoma|T-Cell Large Granular Lymphocyte Leukemia
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Cyclosporine|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|DRUG: Mycophenolate Mofetil|PROCEDURE: Peripheral Blood Stem Cell Transplantation|OTHER: Pharmacological Study|BIOLOGICAL: Rituximab|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Oxygen Changes in the Heart With Cardio-vascular Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Vascular Diseases|Myocardial Ischemia
Interventions: DRUG: adenosine|OTHER: modified end-tidal forcing system|OTHER: arm cuff occlusion|DEVICE: Breathing gas|DEVICE: Blood pressure cuff
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Retrospective Analysis of Neevo®/Neevo®DHA Compared to a Standard Prenatal Vitamin in Anemia During Pregnancy
Status: COMPLETED
Conditions: Anemia in Pregnancy|Preeclampsia
Interventions: OTHER: Neevo® (a medical food)|OTHER: Prenatal vitamins (≤1mg folic acid, 27 - 35mg iron, and ≤12mcg vitamin B12)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pre- vs Postoperative Thromboprophylaxis for Liver Resection
Status: RECRUITING
Conditions: Liver Cancer|Surgery|Thrombosis, Deep Vein|Embolism, Pulmonary|Bleeding
Interventions: DRUG: enoxaparin or tinzaparin or dalteparin|DRUG: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Efficacy and Safety of CMK389 in Patients With Moderate to Severe Atopic Dermatitis.
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: CMK389|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oxidant Status and Effect of Antioxidant in Immune Thrombocytopenia
Status: UNKNOWN
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Antox tablets(Mepaco)|OTHER: drug therapy for ITP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Mandibular Advancement Device for Mild-Moderate Apnea
Status: COMPLETED
Conditions: Apnea
Interventions: DEVICE: Conventional mandibular advancement device|DEVICE: CAD CAM mandibular advancement device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Administration of Small Doses of Thyroxine on Glucose and Lipid Metabolism, in Type 2 Diabetes Mellitus.
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: thyroxine|DRUG: Placebo|OTHER: A meal (730kcal, 50%carbohydrate, of which 38% was starch, 40% fat, and 10% protein)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of SAR341402 to NovoLog/NovoRapid in Adult Patients With Diabetes Mellitus Also Using Insulin Glargine
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus-Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin aspart|DRUG: NovoLog/NovoRapid|DRUG: Insulin glargine (HOE901)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Cilostazol in Patients of Vascular Cognitive Impairment-no Dementia (VCIND)
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: DRUG: Aspirin|DRUG: Cilostazol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Will Glucarpidase After Methotrexate Treatment for Bone Sarcoma Lead to Fewer Side Effects and Reduce Chemotherapy Delays?
Status: TERMINATED
Conditions: Osteosarcoma|Spindle Cell Sarcoma of Bone
Interventions: DRUG: Glucarpidase|DRUG: Methotrexate|DRUG: Folinic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Volunteers Comparing Two Different Liquid Formulations of Solifenacin With Each Other and With the Tablet Formulation
Status: COMPLETED
Conditions: Pharmacokinetics of Solifenacin Succinate|Healthy Volunteers
Interventions: DRUG: Solifenacin Succinate Formulation A|DRUG: Solifenacin Succinate Formulation B|DRUG: Solifenacin Succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Pelvic Area Extension Measurements for Four Types of Lumbopelvic Balance Using Three Different Methods
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: OTHER: Goniometric measure of pelvic extension reserve.|OTHER: Photographic measure of pelvic extension reserve.|OTHER: EOS measure of pelvic extension reserve.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Descriptive, Open-label, Multicenter Study of the Safety of Redosing With ADACEL® Vaccine
Status: COMPLETED
Conditions: Tetanus|Diphtheria|Pertussis
Interventions: BIOLOGICAL: Tetanus-diphtheria-acellular pertussis (Tdap) vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Activated Recombinant Human Factor VII in Patients Undergoing Orthotopic Liver Transplantation
Status: COMPLETED
Conditions: Acquired Bleeding Disorder|Bleeding During/Following Surgery
Interventions: DRUG: activated recombinant human factor VII|DRUG: activated recombinant human factor VII|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Buprenorphine and Integrated HIV Care Evaluation
Status: UNKNOWN
Conditions: Opioid-Related Disorders|HIV Infections|AIDS
Interventions: DRUG: Buprenorphine|BEHAVIORAL: Integrated HIV care and office-based opioid dependence treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Heterologous FMT by SQIMC-md Capsule in Mild-moderate Ulcerative Colitis Patients
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: PROCEDURE: Standardized Quantitative multi-donor Intestinal Microbiota Capsule (SQIMC-md)|PROCEDURE: placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Impact of an Educational Program (EDU-MICI) on Patients With Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Crohn's Disease|Ulcerative Colitis
Interventions: PROCEDURE: Educational program EDU-MICI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Stretching in Children and Adolescents With Spastic Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy, Spastic
Interventions: OTHER: Static stretching|OTHER: Proprioceptive neuromuscular facilitation stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Correlation of Preoperative Global Olfactory Function With Frailty, Perioperative Neurocognitive Disorders and Mortality
Status: ACTIVE_NOT_RECRUITING
Conditions: Frailty|Perioperative/Postoperative Complications|Olfactory Disorder|Neurocognitive Disorders|Postoperative Cognitive Dysfunction
Interventions: DIAGNOSTIC_TEST: Olfactory function testing|DIAGNOSTIC_TEST: Edmonton Frail Scale|DIAGNOSTIC_TEST: Clinical Frailty Scale|DIAGNOSTIC_TEST: Neuropsychological test battery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Breastfeeding Education Given to Primiparous Mothers With the Teach-Back Method
Status: RECRUITING
Conditions: Breastfeeding Self-efficacy
Interventions: DIAGNOSTIC_TEST: breastfeeding education of Teach Back|OTHER: breastfeeding education simple explanation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oral Glutamine in the Prevention of Oxaliplatin-induced Neurotoxicity
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: Glutamine|DRUG: Calcium and Magnesium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Study the Adjuvant Benefits of Quercetin Phytosome in Patients With COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Standard COVID-19 care|DIETARY_SUPPLEMENT: Quercetin Phytosome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2, Randomized, Double-Blind, Placebo-Controlled of the Efficacy and Safety of CF102 in Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: CF102|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 13C Trioctanoate Breath Test as a Measurement of Gastric Fat Volume Emptying
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Octanoic acid (1-13C, 99%)|DIETARY_SUPPLEMENT: TRIOCTANOIN (1,1,1-13C3, 99%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Residual Disease MEMory in PSOriasis Skin During EnstiLAR® and Narrow-band Ultraviolet B Therapy: The MEMPSOLAR Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Psoriasis Vulgaris|Psoriasis|Skin Diseases|Skin Diseases, Papulosquamous|Skin and Connective Tissue Diseases
Interventions: DRUG: Enstilar|DRUG: Placebo-vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Molecular Signatures of Esophageal Atresia
Status: RECRUITING
Conditions: Esophageal Atresia
Interventions: PROCEDURE: Esophageal biopsy collection during anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Spine Research With Roentgen Stereophotogrammetric Analysis
Status: COMPLETED
Conditions: Spondylolisthesis|Degenerative Lumbar Disc Disease|Spinal Stenosis
Interventions: DEVICE: Trabecular Metal Intervertebral Cage with RSA beads
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Pharmacokinetics of PF-04965842 and Its Metabolites and Effect of Probenecid in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-04965842|DRUG: Probenecid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Platelets to Lymphocytes Ratio and Monocytes to Lymphocytes Ratio as Predictors of Response to Treatment in Cirrhotic Patients With Spontaneous Bacterial Peritonitis.
Status: RECRUITING
Conditions: Cirrhotic Patients With Spontaneous Bacterial Peritonitis
Interventions: DIAGNOSTIC_TEST: ascetic fluid study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transcendental Meditation and Yoga: Short- and Long-term Effects in Cardiac Rehabilitation Patients - a Pilot Study
Status: COMPLETED
Conditions: Cardiovascular Diseases|Vascular Diseases|Stress, Psychological
Interventions: OTHER: Transcendental Meditation|OTHER: Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Intravenous Bendavia™ on Reperfusion Injury in Patients Undergoing Angioplasty of the Renal Artery
Status: TERMINATED
Conditions: Renal Artery Obstruction|Hypertension, Renovascular|Ischemia Reperfusion Injury
Interventions: DRUG: Bendavia|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimising Nutrition, Oral Health and Medication for Older Home Care Clients (NutOrMed)
Status: COMPLETED
Conditions: Nutrition, Oral Health
Interventions: OTHER: Nutrition and oral health interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH