pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of Subcutaneous Doses of HIP2B in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HIP2B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Establish a Vegetable Signature Database From Human Metabolomics Responses
Status: UNKNOWN
Conditions: Human Metabolomic Responses to Plant Foods|Blood Pressure
Interventions: OTHER: Low phytochemical diet(LPD), high phytochemical diet(HPD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate The Effect Of Torcetrapib/Atorvastatin In Patients With Genetic High Cholesterol Disorder
Status: COMPLETED
Conditions: Hypercholesterolemia, Familial
Interventions: DRUG: Torcetrapib/atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concordance Between ETCO2, PTCO2 and PaCO2 in the Home-ventilated Neuromuscular Patient
Status: COMPLETED
Conditions: Neuromuscular Disease|Chronic Respiratory Insufficiency|Intermittent Positive-pressure Ventilation
Interventions: DEVICE: Monitoring of ETCO2 and PTCO2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prospective Randomized, Controlled Trial for Treatment of Intraventricular Hemorrhage
Status: UNKNOWN
Conditions: Intraventricular Hemorrhage
Interventions: PROCEDURE: Rt-PA thrombolysis|PROCEDURE: endoscopic hematoma evacuation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Diagnostic Method for Exotropia Using Video-oculography
Status: COMPLETED
Conditions: Strabismus|Exotropia
Interventions: DIAGNOSTIC_TEST: Video-oculography|DIAGNOSTIC_TEST: APCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Estimation of the Localization Accuracy of the Genicular Ablation Procedure Applied for Chronic Pain Suppression
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DEVICE: MRI|PROCEDURE: genicular ablation procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Alpha-2 Agonists for Prevention of Intraocular Pressure Elevation After Selective Laser Trabeculoplasty
Status: UNKNOWN
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: brimonidine 0.1%|DRUG: Apraclonidine 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Named Patient Program for Mitomycin for Pyelocalyceal Solution
Status: AVAILABLE
Conditions: Urothelial Cancer of Renal Pelvis|Urothelial Carcinoma of the Renal Pelvis and Ureter|Urothelial Carcinoma Ureter|Urothelial Carcinoma Ureter Recurrent|Urothelial Carcinoma|Urothelial Carcinoma Recurrent
Interventions: DRUG: Mitomycin for pyelocalyceal solution
Study Type: EXPANDED_ACCESS
Clinical trial: Evaluation of A-1 Cool Cream Efficacy for Treatment Atopic Dermatitis
Status: UNKNOWN
Conditions: ATOPIC DERMATITIS
Interventions: DRUG: A -1 Cool Cream,Vaselin ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Diabetic Foot Infection Antibiotic Study
Status: TERMINATED
Conditions: Diabetic Foot Infections
Interventions: PROCEDURE: Surgical incision and drainage of diabetic foot infection|DRUG: Short course antibiotics|DRUG: Long course antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Vorinostat and Bortezomib in Children With Refractory of Recurrent Solid Tumors, Including CNS Tumors and Lymphomas
Status: COMPLETED
Conditions: Lymphoma|Sarcoma|WilmsTumor|Neuroblastoma
Interventions: DRUG: Vorinostat (SAHA)|DRUG: Velcade (PS-341, Bortezomib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Clarithromycin Treatment in Prevention of Chronic Lung Disease in Premature Infants
Status: COMPLETED
Conditions: Chronic Lung Disease
Interventions: DRUG: Clarithromycin|DRUG: Dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Timing of Micronutrient Powder Consumption on Iron Absorption in Infants
Status: COMPLETED
Conditions: Anemia|Iron Deficiency
Interventions: DIETARY_SUPPLEMENT: Fortified maize porridge (MNP and Iron)|DIETARY_SUPPLEMENT: Fortified Maize porridge (MNP + Iron + GOS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigation of Lithium on Signal Transduction, Gene Expression and Brain Myo-Inositol Levels in Manic Patients
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Lithium Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: CT-322 in Combination With Radiation Therapy and Temozolomide to Treat Newly Diagnosed Glioblastoma Multiforme
Status: UNKNOWN
Conditions: Glioblastoma Multiforme
Interventions: DRUG: CT-322|DRUG: Temozolomide|PROCEDURE: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparability of Transesophageal Echocardiography and FloTrac/Vigileo System Three Different Positions
Status: COMPLETED
Conditions: Cardiac Output
Interventions: DEVICE: FloTrac/Vigileo system (© Edwards Lifesciences) (Edwards Lifesciences, Irvine, CA) device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: S1304, Carfilzomib and Dexamethasone for Treating Patients With Relapsed or Refractory Myeloma
Status: COMPLETED
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Dexamethasone|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of BAY86-5300 With an Extended Flexible Regimen for Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: EE20/DRSP(BAY86-5300)|DRUG: Placebo|DRUG: Dienogest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study for Development of Oral Galactose Single Point (OGSP) Solution (G.S.P. Oral Solution®)
Status: UNKNOWN
Conditions: Galactose Single Point (GSP), Residual Liver Function
Interventions: DRUG: G.S.P. Oral Solution 400 mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Oral Vitamin A Supplementation in Neonates With Birth Weight < 1500 g
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia|Retinopathy of Prematurity
Interventions: DIETARY_SUPPLEMENT: Vitamin A oral drops
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tirzepatide in Overweight and Very Overweight Participants
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DRUG: Tirzepatide|DRUG: Placebo|DRUG: Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sutent Adjunctive Treatment of Differentiated Thyroid Cancer
Status: COMPLETED
Conditions: Papillary Thyroid Cancer|Follicular Thyroid Cancer|Differentiated Thyroid Cancer
Interventions: DRUG: SU011248, Sutent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COgnitive-somatoSensory-MOtor Training to Improve Arm and Hand Function After Stroke (iCOSMO)
Status: NOT_YET_RECRUITING
Conditions: Stroke|CVA|Cerebrovascular Accident
Interventions: OTHER: Home Graded Repetitive Arm Supplementary Program (GRASP)|OTHER: integrated Somatosensory-MOtor training using a COgnitive approach(iCOSMO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy, Safety and Pharmacokinetics of Intravenous Conivaptan (Vaprisol®) in Pediatric Subjects With Euvolemic or Hypervolemic Hyponatremia
Status: TERMINATED
Conditions: Hyponatremia
Interventions: DRUG: Conivaptan hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Hypertonic Lactate Solution in CABG(Coronary Artery Bypass Grafting) Patients
Status: COMPLETED
Conditions: Low Cardiac Output
Interventions: DRUG: Hypertonic lactate|DRUG: Ringer's lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-gene-nutraceutical Interactions of Cannabidiol and Tacrolimus
Status: RECRUITING
Conditions: CBD|Transplant Complication|Kidney Disease, Chronic
Interventions: DRUG: Tacrolimus single dose|DRUG: Epidiolex single dose|DRUG: Epidiolex steady-state and tacrolimus single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Mobile Gaming App to Improve ART Adherence for Youth
Status: ENROLLING_BY_INVITATION
Conditions: Medication Adherence|HIV/AIDS
Interventions: BEHAVIORAL: Multilevel Gaming Adherence Intervention|BEHAVIORAL: Treatment as Usual +
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Tolerability of Using an Oral Once-daily 2 Drug Regimen Compared to an Oral Once-daily 3 Drug Regimen for the Treatment of Human Immunodeficiency Virus (HIV)-1 in Adults Who Have Not Previously Taken Antiretroviral Therapy
Status: RECRUITING
Conditions: HIV|HIV Infections
Interventions: DRUG: Dolutegravir|DRUG: Lamivudine|DRUG: Bictegravir|DRUG: Emtricitabine|DRUG: Tenofovir alafenamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MyeloGen: Germline Testing for Predisposition to Myeloid Malignancies
Status: NOT_YET_RECRUITING
Conditions: Myeloid Malignancy|Myeloid Malignancies|Blood Cancer|Blood Cancers
Interventions: OTHER: Genetic Blood Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Treatment of Papillary Thyroid Carcinoma With Radiofrequency Ablation
Status: ACTIVE_NOT_RECRUITING
Conditions: Papillary Thyroid Cancer|Papillary Thyroid Microcarcinoma
Interventions: DEVICE: RFA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychological Assessment and Treatment of Chronic Benign Headache
Status: COMPLETED
Conditions: Headache|Migraine|Tension Headache|Stress Headache|Vascular Headache
Interventions: BEHAVIORAL: Relaxation training & thermal biofeedback|BEHAVIORAL: Surface EMG biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalised Prospective Comparison of ARni With ArB in Patients With Natriuretic Peptide eLEvation
Status: UNKNOWN
Conditions: Atrial Remodeling|Myocardial Dysfunction|Left Ventricular Remodeling|Left Ventricular Diastolic Dysfunction|Hypertension|Cardiovascular Morbidity|Fibrosis Myocardial|Inflammatory Myopathy|Atrial Arrhythmia
Interventions: DRUG: Sacubitril-Valsartan|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Real-world Study of Trifluridine/Tipiracil Containing Regimen for the Treatment of Patients With mCRC (REFLECT Study)
Status: NOT_YET_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Trifluridine/Tipiracil
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 1 Study in Healthy Subjects to Evaluate the Effect of IPI-145 on the Pharmacokinetics of Midazolam
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: IPI-145|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Safety, Tolerability, and Pharmacokinetics of Multiple Ascending Doses of REGN3500 in Adults With Moderate Asthma
Status: COMPLETED
Conditions: Asthma|Moderate Asthma
Interventions: DRUG: REGN3500|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Adjuvant Platinum and Taxane in Triple-negative Breast Cancer (PATTERN)
Status: COMPLETED
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Paclitaxel Cisplatin|DRUG: fluorouracil epirubicin cyclophosphamide and docetaxel (FEC-T)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Assessment of Interconnection Between Brain Emotional Activity and Coronary Plaque Instability
Status: RECRUITING
Conditions: Atherosclerosis, Coronary|Emotional Stress|Inflammation|Hematopoiesis|Atherosclerosis Coronary Artery With Angina Pectoris|Atheroma; Heart|Atherosclerosis|Acute Coronary Syndrome
Interventions: DEVICE: OCT-FLIM (optical coherence tomography-fluorescence life time)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial With Vinflunine as Maintenance Therapy in Metastatic Urothelial Cancer
Status: COMPLETED
Conditions: Carcinoma, Transitional Cell
Interventions: DRUG: Vinflunine|OTHER: Undefined (standard care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Obstetric, Fetal and Neonatal Risks and Vertical SARS-CoV-2 Transmission During COVID-19 Pandemic
Status: COMPLETED
Conditions: Pregnancy
Interventions: DIAGNOSTIC_TEST: COVID 19 diagnostic test by PCR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Normalization of dyrk1A and APP Function as an Approach to Improve Cognitive Performance and Decelerate AD Progression in DS Subjects: Epigallocatechin Gallate as Therapeutic Tool
Status: COMPLETED
Conditions: Down Syndrome (DS)
Interventions: DIETARY_SUPPLEMENT: Epigallocatechin-3-gallate (EGCG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Plus Cisplatin Versus Gemcitabine Plus Carboplatin in Triple Negative Breast Cancer (TNBC)
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Gemcitabine,cisplatin|DRUG: Gemcitabine,carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Height Gain Following Transcrestal Sinus Floor Elevation Using Piezoelectric Surgery Versus The Conventional Osteotome Technique
Status: COMPLETED
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: piezoelectric device|PROCEDURE: Summers technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Uterine Lidocaine Flushing in HyFoSy
Status: UNKNOWN
Conditions: To Evaluate the Efficacy of Flushing the Uterine Cavity With Lidocaine Before Hysterosalpingo-Foam Sonography to Reduce Procedure-related Pain
Interventions: DRUG: 2% lidocaine|DRUG: 0.9 % normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy
Status: RECRUITING
Conditions: Malignant Solid Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Cryocompression Therapy|PROCEDURE: Pneumatic Compression Therapy|PROCEDURE: Pneumatic Compression Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Optimal Antiplatelet Therapy Following Left Atrial Appendage Closure in Dialyzed Patients
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: short postimplantation dual antiplatelet therapy|DRUG: extended postimplantation dual antiplatelet therapy|DRUG: long-term treatment with a single antiplatelet agent|DRUG: 6 months treatment with a single antiplatelet agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intramyocardial Injection of Autologous Umbilical Cord Blood Derived Mononuclear Cells During Surgical Repair of Hypoplastic Left Heart Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypoplastic Left Heart Syndrome
Interventions: BIOLOGICAL: Autologous (self) mononuclear cells derived from umbilical cord blood|PROCEDURE: Stage II Surgical repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: L Brevis for Traumatic Oral Lesions in Orthodontic Patients
Status: COMPLETED
Conditions: Orthodontic Appliance Complication|Oral Mucositis|Bacterium; Agent
Interventions: DRUG: L brevis|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Typical Flutter Ablation:A Comparison of 4 mm Versus 2 mm Irrigated cathéters
Status: UNKNOWN
Conditions: Typical Atrial Flutter|Radiofrequency Ablation|Irrigated Catheters
Interventions: PROCEDURE: Radiofrequency ablation for atrial flutter by catheters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irritable Bowel Syndrome and Osteopathic Manipulative Therapy
Status: TERMINATED
Conditions: Irritable Bowel Syndrome
Interventions: PROCEDURE: osteopathic session|PROCEDURE: Placebo manipulative session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Continuation Protocol for Patients Previously Enrolled in a Study of Toca 511
Status: TERMINATED
Conditions: Glioblastoma Multiforme|Astrocytoma|Gliomas, Malignant
Interventions: BIOLOGICAL: Toca 511 vector|DRUG: Toca FC • Flucytosine • 5-FC • 5-Fluorocytosine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Multiple Subcutaneous Injections of ABT-981 in Patients With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: BIOLOGICAL: ABT-981|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trials for the Prevention of Gallstone Formation After Gastrectomy in Patient With Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: DWJ1319|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Long-term Effect on Intestinal Absorption and Safety of Treatment With Glepaglutide in Patients With Short Bowel Syndrome
Status: COMPLETED
Conditions: Short Bowel Syndrome
Interventions: DRUG: Glepaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Indacaterol With That of Placebo in 'Maintenance naïve' Patients With COPD Using Blinded Tiotropium as Active Control
Status: WITHDRAWN
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Indacaterol|DRUG: Placebo to tiotropium|DRUG: Tiotropium|DRUG: Placebo to indacaterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Confirm the Clinical Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in Subjects With T1DM
Status: COMPLETED
Conditions: Hypoglycemia|Diabetes Mellitus, Type 1
Interventions: DRUG: Dasiglucagon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Pomona Household Universal Grant (HUG) Program
Status: RECRUITING
Conditions: Early Child Well-being|Parental Stress|Family Economic Security|Parental/Caregiver Health|Mental Health
Interventions: BEHAVIORAL: Guaranteed Income ($500/monthly)|BEHAVIORAL: Active Comparison ($20/monthly)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Immune Cell Changes in the Genital Tract 2 Months After Initiation of an IUD for Contraception
Status: COMPLETED
Conditions: Genital Tract Mucosal Immunity|Genital Tract Microflora
Interventions: DRUG: IUD placement|DRUG: Levonorgestrel IUD|DRUG: Copper T380A IUD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of SyB L-0501 for Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: SyB L-0501
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Therapeutic Effect of Rectal Vs. Intravenous Paracetamol in The Treatment of Patent Ductus Arteriosus (PDA) in Neonates
Status: NOT_YET_RECRUITING
Conditions: Patent Ductus Arteriosus
Interventions: DRUG: Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New Magnetic Resonance Imaging Biomarkers in Amyotrophic Lateral Sclerosis
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: OTHER: Muscular MRI|OTHER: Electrophysiological exam|OTHER: Brain MRI|OTHER: Spinal cord MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pregabalin Treatment Of Peripheral Neuropathic Pain Associated With Diabetic Peripheral NeP (DPN), Postherpetic Neuralgia (PHN), HIV-related NeP (HIV), and Chemotherapy Induced NeP
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathic Pain (DPN)|Postherpetic Neuralgia (PHN)|HIV-related Neuropathic Pain (HIV)|Chemotherapy Induced Neuropathic Pain
Interventions: DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contrast-Enhanced Cone Beam Breast CT for Diagnostic Breast Imaging
Status: TERMINATED
Conditions: Breast Cancer
Interventions: RADIATION: Contrast Enhanced Cone Beam Breast CT Scan|DRUG: Contrast Dye, Iodinated
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Evaluating the Effect of Filgotinib in Participants With Active Axial Spondyloarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Axial Spondyloarthritis
Interventions: DRUG: Filgotinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Stem Cell Transplant for CLL
Status: TERMINATED
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation Recipient|Chronic Lymphocytic Leukemia|Prolymphocytic Leukemia|Richter Syndrome
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|BIOLOGICAL: Anti-Thymocyte Globulin|DRUG: Busulfan|DRUG: Clofarabine|BIOLOGICAL: Filgrastim|DRUG: Gemcitabine|DRUG: Methotrexate|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bilateral Dispensing Clinical Trial of Sapphire Lens Against Senofilcon A Lens Over 2 Weeks
Status: COMPLETED
Conditions: Myopia|Hyperopia
Interventions: DEVICE: Sapphire|DEVICE: senofilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Measuring Changes in Blood in Patients at High Risk of Cytomegalovirus Infection After Undergoing Donor Bone Marrow Transplant or Peripheral Blood Stem Cell Transplant
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Nonneoplastic Condition
Interventions: DRUG: ganciclovir|GENETIC: polymerase chain reaction|OTHER: flow cytometry|OTHER: immunologic technique|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: assessment of therapy complications|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Scalable Communication Modalities for Returning Genetic Research Results
Status: RECRUITING
Conditions: Hereditary Breast and Ovarian Cancer|Lynch Syndrome
Interventions: BEHAVIORAL: Online modality|BEHAVIORAL: Genetic counselor follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Chocolate and Physical Exercise to Reduce Malnutrition in Pre-dementia Aged People
Status: RECRUITING
Conditions: Dementia|Dementia, Mild|Dementia Moderate|Dementia Senile|Malnutrition|Deficiency Nutritional|Deficiency Diseases
Interventions: BEHAVIORAL: Combination of High Protein Diet and Physical Exercise protocol|DIETARY_SUPPLEMENT: HPP Choko|DIETARY_SUPPLEMENT: HPP/VE Choko
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Behavioural Effects of Souroubea-Platanus in Healthy Volunteers
Status: COMPLETED
Conditions: Anxiety|Stress, Psychological
Interventions: OTHER: Souroubea-Platanus Preparation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MONO: Symbicort® Single Inhaler Therapy and Conventional Best Standard Treatment for the Treatment of Persistent Asthma in Adolescents and Adults
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide/Formoterol Turbuhaler|DRUG: Conventional Best Asthma Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-CD19 CAR-T Cell Therapy in Participants With Moderate to Severe Active Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Safety|Effective
Interventions: DRUG: RD06-04 Cells injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stromal Vascular Fraction Enriched PRP in Treatment of Post-acne Scars
Status: NOT_YET_RECRUITING
Conditions: Acne Scars - Atrophic
Interventions: BIOLOGICAL: Stromal vascular fraction (SVF) enriched platelet rich plasma (PRP) versus each alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ciliary Neurotrophic Factor (CNTF) Safety Trial in Patients With Macular Telangiectasia (Mactel)
Status: COMPLETED
Conditions: Idiopathic Juxtafoveal Telangiectasia
Interventions: BIOLOGICAL: NT-501 implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VA HDL Intervention Trial (VA-HIT) Ancillary Study Data Analysis
Status: COMPLETED
Conditions: Coronary Disease|Heart Diseases|Cardiovascular Diseases|Carotid Artery Diseases|Diabetes Mellitus, Non-insulin Dependent|Hypertension|Insulin Resistance|Obesity|Diabetes Mellitus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Polygen Defi-Alpha: Genetic Polymorphisms Study in Children With Alpha-1 Antitrypsin Deficiency, Included in the DEFI-ALPHA Cohort
Status: COMPLETED
Conditions: Children With a Deficiency of Alpha-1 Antitrypsin
Interventions: OTHER: blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety And Pharmacokinetic Assessment Of Orally Administered Tafamidis In Healthy Volunteers
Status: COMPLETED
Conditions: TTR Cardiomyopathy
Interventions: DRUG: Tafamidis|DRUG: Tafamidis|DRUG: Tafamidis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison Different Method Treatment in Tuberosity Fractures of the Proximal Fifth Metatarsal
Status: COMPLETED
Conditions: Muscle Weakness|Metatarsal Fracture|Healing Fracture of Bone
Interventions: PROCEDURE: Symptomatic Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Periganglionic Resiniferatoxin for the Treatment of Intractable Pain Due to Cancer-induced Bone Pain
Status: NOT_YET_RECRUITING
Conditions: Intractable Pain|Palliative Care
Interventions: DRUG: Resiniferatoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Barbed and Non-barbed Suture for Uterine Incision Closure at Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section
Interventions: DEVICE: Knotless barbed suture|DEVICE: polyglactin 910
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Telephone-Based Smoking Cessation Program Among People in the Military (The AFIII Study)
Status: COMPLETED
Conditions: Smoking|Smoking Cessation
Interventions: DRUG: Nicotine Patch|BEHAVIORAL: Tobacco Quit Line Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing the NYU Electronic Patient Visit Assessment (ePVA) for Head and Neck Cancer In Rural and Urban Populations
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: BEHAVIORAL: NYU Electronic Patient Visit Assessment (ePVA)|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Opioid Analgesia on Circulating Tumor Cells in Open Colorectal Cancer Surgery
Status: COMPLETED
Conditions: Colorectal Cancer|Circulating Tumor Cell
Interventions: DRUG: Morphine|DRUG: Piritramid|DRUG: Epidural
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avocado Snacks in a Prediabetic Population
Status: ACTIVE_NOT_RECRUITING
Conditions: PreDiabetes
Interventions: OTHER: Avocado|OTHER: low fat yogurt|OTHER: low fat yogurt + fiber +fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Short Wave Diathermy Added on Dextrose Prolotherapy Injections in Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Short wave diathermy|OTHER: Prolotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Auscultation, Lus, Fob In Olv (ALFIO)
Status: UNKNOWN
Conditions: Thoracic Anesthesia|Lung Ultrasound|Left Double-lumen Tube|Selective Bronchial Intubation|One-lung Ventilation|Auscultation|Flexible Bronchoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiation Therapy in Treating Patients With Bile Duct, Gallbladder, or Pancreatic Cancer
Status: COMPLETED
Conditions: Extrahepatic Bile Duct Cancer|Gallbladder Cancer|Pancreatic Cancer
Interventions: DRUG: motexafin gadolinium|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: COVID-19 Resource Offers Among Rent and Utility Assistance Applicants in St. Louis
Status: COMPLETED
Conditions: Behavior and Behavior Mechanisms|Communication
Interventions: OTHER: Door-In-The-Face Technique|OTHER: Foot-In-The-Door Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Postoperative Pain and Discomfort After Orbital Decompression
Status: COMPLETED
Conditions: Surgery|Anesthesia|Pain
Interventions: DRUG: Nalbuphine|DRUG: Flurbiprofen Axetil|DRUG: Nalbuphine and Flurbiprofen Axetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Benzoyl Peroxide and Electrocautery Skin Incision to Eradicate Cutibacterium Acnes
Status: WITHDRAWN
Conditions: Prosthetic-joint Infection
Interventions: DRUG: Benzoyl Peroxide Topical|PROCEDURE: Electrocautery surgical skin incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Healthy Volunteer Trial to Gain Information About the Blood Concentrations of PF-06412562 After Oral Administration of a Modified Release Formulation in Fasted and Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 3 mg PF-06412562 MR tablets_Fasted|DRUG: 2 x 15 mg PF-06412562 MR tablets_Fasted|DRUG: 2 x 15 mg PF-06412562 MR tablets_Fed|DRUG: 10 mg PF-06412562 IR tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Observation on the Efficacy of Improving Ankle Dorsiflexion Limitation in Patients With Plantar Fasciitis
Status: RECRUITING
Conditions: Plantar Fasciitis
Interventions: BEHAVIORAL: Intervention plan for improving ankle dorsiflexion limitation group (experimental group)|BEHAVIORAL: Plantar fasciitis routine rehabilitation group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Micronutrient Supplements on Growth and Educational Achievement of Schoolchildren in Bangladesh
Status: UNKNOWN
Conditions: Micronutrient Deficiencies
Interventions: DIETARY_SUPPLEMENT: Multiple micronutrients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Convergence Insufficiency Treatment Trial (CITT)
Status: UNKNOWN
Conditions: Convergence Insufficiency|Binocular Vision Disorder
Interventions: BEHAVIORAL: Home-based Pencil Push-Up Therapy|BEHAVIORAL: Home-based Pencil Push-ups with Computer Vision Therapy/Orthoptics|BEHAVIORAL: Office-based Vision Therapy/Orthoptics|BEHAVIORAL: Placebo Office-based Vision Therapy/Orthoptics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Light Therapy in Insomnia Disorder
Status: NOT_YET_RECRUITING
Conditions: Insomnia
Interventions: OTHER: Placebo with light therapy glasses|OTHER: light therapy with light therapy glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study to Determine the Maximum Tolerated Dose (MTD) and Safety of CC-4047 (Pomalidomide) Administered in Conjunction With Cisplatin and Etoposide
Status: TERMINATED
Conditions: Carcinoma, Small Cell
Interventions: DRUG: Pomalidomide|DRUG: Cisplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Fecal Microbiota Transplantation
Status: RECRUITING
Conditions: Fecal Microbiota Transplantation
Interventions: PROCEDURE: Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Preliminary Study to Explore Clinical Endpoints in Patients (Male) With Diarrhea-predominant Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Ramosetron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Study to Evaluate the Efficacy of Modafinil Treatment in Patients With Attention Deficit Hyperactivity Disorder (ADHD) Who Are Responders to Modafinil Treatment
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Short-term Motor Training on Accuracy and Precision of Knee Movement in Human With and Without Knee Pain
Status: COMPLETED
Conditions: Isotonic Saline|Hypertonic Saline|Healthy Eld Human|Knee Pain Chronic
Interventions: DRUG: Hypertonic saline|DRUG: isotonic saline|OTHER: Motor training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Long-term (12 Months) Safety, Tolerability and Efficacy Study of LCZ696 in Patients With Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: LCZ696|DRUG: Amlodipine|DRUG: Hydrochlorothiazide (HCTZ)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Directly Observed Hepatitis C Treatment in Methadone Clinics
Status: COMPLETED
Conditions: Hepatitis C|Medication Adherence
Interventions: OTHER: enhanced DOT (both pegylated interferon alfa-2a and ribavirin)|OTHER: standard DOT (PEG-DOT control arm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study for Toxicity Evaluation of HIV Rectal Microbicides
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Normosol-R|DRUG: Nonoxynol-9|PROCEDURE: Gastrointestinal instrumentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of ACP-196 (Acalabrutinib) in Subjects With Relapsed/Refractory CLL and Intolerant of Ibrutinib Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: ACP-196 (acalabrutinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benralizumab in Patients With Inadequate Response to Anti-IL5 Monoclonal Antibody Therapies
Status: COMPLETED
Conditions: Severe Prednisone Dependent Eosinophilic Asthma
Interventions: BIOLOGICAL: Benralizumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: BULLET: Bladder Ultrasound Limits Length (of Time), Expedites Treatment
Status: COMPLETED
Conditions: Point-of-Care Bladder Ultrasound|Urethral Catheter
Interventions: DEVICE: Bladder Ultrasound|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: STEM-Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease|Parkinson's Disease and Parkinsonism
Interventions: DEVICE: Non-invasive brainstem stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Topical Trimebutine on Pain After Hemorrhoidectomy
Status: SUSPENDED
Conditions: Hemorrhoids
Interventions: DRUG: Trimebutine|PROCEDURE: Hemorrhoidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Caudal Epidural Steroid and Trigger Point Injection
Status: RECRUITING
Conditions: Myofascial Trigger Point Pain
Interventions: DRUG: Trigger point injection (lidocaine)|DRUG: Caudal epidural Group (bupivacaine + triamcinolone + NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: "Improved Mother Infant Feeding Interaction (MI-FI) at 12 Months With Very Early Parent Training"
Status: COMPLETED
Conditions: Picky Eaters, Feeding Interaction, Good Enough Parenting, Family Meals, Emotional Eating Prevention
Interventions: BEHAVIORAL: Mother Infant Feeding Interaction very early training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Extension of ALT-801 in Diabetic and Non-Diabetic Overweight and Obese Subjects With (NAFLD)
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DRUG: ALT-801|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating an eHealth Breastfeeding Resource
Status: UNKNOWN
Conditions: Breastfeeding, Exclusive|Breastfeeding
Interventions: OTHER: eHealth Breastfeeding Co-parenting Resource
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial to Evaluate the Effect of a Probiotic Mixture on the Rosacea Evolution
Status: RECRUITING
Conditions: Rosacea|Rosacea Papular Type|Rosacea, Papulopustular
Interventions: DIETARY_SUPPLEMENT: Probiotic mixture|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Non-Surgical Periodontal Treatment on Bone Metabolism in Type 2 Diabetes and Systemically Healthy Individuals
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: DIAGNOSTIC_TEST: ELISA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: TPF Plus Radiotherapy and Cetuximab to Avoid Total Laryngectomy in Patients With Larynx Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: TPF, radiotherapy and cetuximab|PROCEDURE: H&N surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Radioimmunotherapy (111Indium/225Actinium-DOTA-daratumumab) for the Treatment of Relapsed/Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: BIOLOGICAL: Actinium Ac 225-DOTA-Daratumumab|BIOLOGICAL: Daratumumab|BIOLOGICAL: Indium In 111-DOTA-Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Novel Sound Changing Principles in Hearing Instruments to Determine Their Application - 2019_20
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Hearing Aid with standard Noise Reduction (NR_1)|DEVICE: Hearing Aid with NR_2|DEVICE: Hearing Aid with NR_3|DRUG: Hearing Aid with NR_4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT