pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluate the Efficacy and Safety of Atorvastatin Combined With Temozolomide in the Treatment of Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma, IDH-wildtype
Interventions: DRUG: Atorvastatin 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AVELUMAB and CETUXIMAB and mFOLFOXIRI as Initial Therapy for Unresectable Metastatic Colorectal Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: 5Fluorouracil|DRUG: L-leucovorin|DRUG: Irinotecan|DRUG: Oxaliplatin|DRUG: Cetuximab|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Tibial Osteotomy With/Without Arthroscopy.
Status: UNKNOWN
Conditions: Osteoarthritis, Knee|Meniscus; Degeneration
Interventions: PROCEDURE: HTO|PROCEDURE: Arthroscopy treatment|PROCEDURE: Micro fractures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluate the PK, Safety, Tolerability of Ferric Maltol at 3 Dosage Levels in Paediatric Subjects With Iron Deficiency
Status: COMPLETED
Conditions: Iron Deficiency, Anaemia in Children|Iron-Deficiency
Interventions: DRUG: Ferric Maltol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Keeping Oral o Parental AnticoaguLation in the Acute Phase of Cardioembolic Ischemic Stroke
Status: UNKNOWN
Conditions: Cardioembolic Stroke|Anticoagulant Therapy|Stroke Recurrence|Haemorrhagic Transformation Stroke
Interventions: OTHER: Observation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prediction of Expected Length of Hospital Stay Using Machine Learning
Status: UNKNOWN
Conditions: Infection|Heart Failure|Chronic Obstructive Pulmonary Disease|Asthma|Gout Flare|Chronic Kidney Diseases|Hypertensive Urgency|Atrial Fibrillation Rapid|Anticoagulants; Increased
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Prebiotic Inulin on Patients Affected by R/M HNSCC Treated With Immune Checkpoint Inhibitors
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DIETARY_SUPPLEMENT: inulin|DRUG: Pembrolizumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRevention Using EPA Against coloREctal Cancer
Status: COMPLETED
Conditions: Colorectal Adenoma|Colorectal Cancer|Endoscopic Surgery|Eicosapentaenoic Acid|Gastrointestinal Microbiome
Interventions: DRUG: AMR101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Open-label, Uncontrolled Phase II Trial of Intravenous PI3K Inhibitor BAY80-6946 in Patients With Relapsed, Indolent or Aggressive Non-Hodgkin's Lymphomas
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: Copanlisib (Aliqopa, BAY80-6946)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI-Ultrasound Fusion or Cognitive Registration in MR-targeted Prostate Biopsy
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: PROCEDURE: Cognitive registration targeted biopsy and TRUS-system biopsy|PROCEDURE: MRI-ultrasound fusion targeted biopsy and TRUS-system biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Tumor Treating Fields With Chemoradiation in Newly Diagnosed GBM
Status: TERMINATED
Conditions: Glioblastoma|Cancer of Brain|Glioblastoma Multiforme|Brain Tumor
Interventions: DEVICE: Tumor Treating Fields|DRUG: Temozolomide|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Efficacy and Safety of DR-2011 for In Vitro Fertilization
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: DR-2011|DRUG: Crinone 8%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pulsatile IV Insulin Delivery on Diabetic Retinopathy in Patients With Types 1 and 2 Diabetes Mellitus
Status: TERMINATED
Conditions: Diabetes Mellitus, With Complications
Interventions: PROCEDURE: Pulsatile IV Insulin|PROCEDURE: Effects of Pulsatile IV Insulin on Diabetic Retinopathy|PROCEDURE: Effects of Pulsatile IV Insulin on Diabetic Retinopathy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Young Adult Hypertension Self-Management Clinical Trial
Status: COMPLETED
Conditions: Hypertension|Blood Pressure|Lifestyle Risk Reduction
Interventions: BEHAVIORAL: Home Blood Pressure Monitoring|BEHAVIORAL: Telephone Health Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SWOG-9304 Chemotherapy Plus Radiation Therapy in Treating Patients With Rectal Cancer That Has Been Surgically Removed
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: levamisole hydrochloride|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Use of a Bioinductive Graft in Treating Massive Rotator Cuff Tears
Status: RECRUITING
Conditions: Rotator Cuff Tear|Rotator Cuff Injury
Interventions: DEVICE: Regeneten|PROCEDURE: Debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Belimumab in Patients With Chronic Lymphocytic Leukemia
Status: RECRUITING
Conditions: Chronic Lymphoid Leukemia in Relapse
Interventions: DRUG: Belimumab 200 MG/ML [Benlysta]|DRUG: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemoradiation in Locally Advanced Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: recombinant interferon alfa|DRUG: cisplatin|DRUG: fluorouracil|RADIATION: radiation therapy|PROCEDURE: Resection of tumor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Twelve Hours Duration of MgSO4 in the Treatment of Eclampsia in Low Resource Setting in Sudan
Status: UNKNOWN
Conditions: Pre-Eclampsia
Interventions: DRUG: Adminstration of magnesium Sulphate for treatment of eclampsia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Golimumab (CNTO148) in Patients With Active Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: CNTO 148|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: VITAL-IMPACT: Improving Cardiometabolic Health in Black Individuals Through Therapeutic Augmentation of Cyclic Guanosine Mono-Phosphate Signaling Pathway
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases|Insulin Sensitivity/Resistance|Metabolic Disease|Metabolism|Energy Expenditure|Obesity
Interventions: DRUG: Vericiguat 10 MG|OTHER: Placebo|OTHER: Insulin Sensitivity Test|OTHER: Resting Energy and Exercise Energy Expenditure Assessment|OTHER: White Adipose Tissue Biopsy|OTHER: MRI-PET Scan for Brown Adipose Tissue Volume Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Efficacy and Safety of Darunavir Boosted With Ritonavir to HART With 2 NRTI and Darunavir Boosted With Ritonavir in HIV-1 Infected Patients ANRS136
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Darunavir|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Liquids Intake in Vasovagal Reaction After Whole Blood Donation
Status: COMPLETED
Conditions: Blood Donation
Interventions: DRUG: Oral Rehydration Salts power (iii)|DIETARY_SUPPLEMENT: water with white granulated sugar|DIETARY_SUPPLEMENT: water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Psychosomatic, Physical Activity or Both for Post-covid19 Syndrom
Status: RECRUITING
Conditions: Post-COVID-19 Syndrome
Interventions: BEHAVIORAL: Exercise Therapy|BEHAVIORAL: Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiotherapy and Surgery for Early-stage Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Hepatectomy|Stereotactic Body Radiotherapy
Interventions: PROCEDURE: laparoscopic hepatectomy (surgery)|RADIATION: stereotactic body radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Pinaverium Bromide on Bile Duct and Pancreatic Duct Cannulation During Endoscopic Retrograde Cholangiopancreatography
Status: UNKNOWN
Conditions: Bile Duct Diseases
Interventions: DIETARY_SUPPLEMENT: pinaverium bromide|DIETARY_SUPPLEMENT: Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Understand and Predict the Failure of Shoulder Fracture Fixations Using Computer Simulations
Status: COMPLETED
Conditions: Proximal Humeral Fracture
Interventions: DIAGNOSTIC_TEST: Post-Operative (OP) Computer Tomography (CT)|OTHER: Questionnaires on patient activity and comorbidities|OTHER: Grip strength measurement|OTHER: Non-invasive shoulder activity tracking usinig wearable sensors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Renal Denervation Using the Vessix Renal Denervation System for the Treatment of Hypertension (REDUCE HTN:REINFORCE)
Status: COMPLETED
Conditions: Hypertension
Interventions: DEVICE: Renal Denervation (Vessix)|DEVICE: Renal Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate a Quality Improvement Intervention to Reduce Wound Separation Rates in Obese Gynecologic Oncology Service Patients Undergoing Abdominal Surgery
Status: COMPLETED
Conditions: Wound Complications|Wound Infection|Wound Separation
Interventions: PROCEDURE: Prospective wound complication protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid for the Prevention of Blood Loss in High Risk Delivered Women
Status: COMPLETED
Conditions: Postpartum Hemorrhage|High Risk Pregnancy|Tranexamic Acid|Third-Stage Postpartum Hemorrhage, With Delivery
Interventions: DRUG: Tranexamic acid injection|OTHER: Glucose water 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical and Laboratorial Evaluation of the Desinfection Solutions in Candida Species From Total Prostheses and Palate of Total Edentulous.
Status: COMPLETED
Conditions: Candidiasis|Biofilms|Candida Infection
Interventions: OTHER: Disinfection Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Group Intervention for Children With Chronic Tics Syndrome or Tourette Syndrome: CBIT vs Psycho-Educational Intervention
Status: UNKNOWN
Conditions: Tourette Syndrome|Motor or Vocal Tic Disorder, Chronic
Interventions: BEHAVIORAL: CBIT group|BEHAVIORAL: Psycho-Educational group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tarceva, Capecitabine and Oxaliplatin for Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Neoplasm Metastasis
Interventions: DRUG: Tarceva (OSI-774)|DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Evaluation of the Intralesional Recombinant Human Epidermal Growth Factor (rhEGF) in Subjects With Diabetic Foot Ulcer.
Status: ACTIVE_NOT_RECRUITING
Conditions: Foot Ulcer, Diabetic|Epidermal Growth Factor
Interventions: DRUG: recombinant human Epidermal Growth Factor (rhEGF)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High-Resolution Assessment of Extracranial Plaques in a Multiple Centers Evolocumab Randomized Study
Status: RECRUITING
Conditions: Cerebral Atherosclerosis
Interventions: DRUG: Evolocumab 140 MG/ML|DRUG: Intensive statin treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Time Restricted Feeding, Muscle, and Metabolism
Status: UNKNOWN
Conditions: Overweight|Obesity
Interventions: DIETARY_SUPPLEMENT: Whey protein supplement|DIETARY_SUPPLEMENT: Ketogenic aid|OTHER: Control group - time restricted feeding only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Comparison of Strategies to PREPARE Severely CALCified Coronary Lesions Trial (PREPARE-CALC)
Status: COMPLETED
Conditions: Coronary Atherosclerosis Due to Severely Calcified Coronary Lesion
Interventions: DEVICE: Rotational Atherectomy|DEVICE: Cutting/Scoring Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Respiratory Muscle Training in ICU Patients
Status: UNKNOWN
Conditions: Critical Illness|Inspiratory Muscle Strength|Mechanical Ventilation|Respiratory Muscle Training
Interventions: PROCEDURE: inspiratory and expiratory muscle training|PROCEDURE: inspiratory and expiratory exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Micro Fragmented Adipose Tissue (MFAT) on Shoulder Osteoarthritis
Status: RECRUITING
Conditions: Osteoarthritis Shoulder|Shoulder Pain
Interventions: BIOLOGICAL: Micro Fragmented Adipose Tissue|BIOLOGICAL: Corticosteroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Food Supplements Based on Nettle and Peppermint to Control Signs and Symptoms Induced by Cancer Therapies
Status: UNKNOWN
Conditions: Breast Cancer|Gynecologic Cancer
Interventions: DIETARY_SUPPLEMENT: Stinging Nettle|DIETARY_SUPPLEMENT: Stinging Nettle|DIETARY_SUPPLEMENT: Peppermint
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Manipulating Narrative Presentations of Information to Encourage Good Foot Care Practice in People With and Without Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetic Foot|Health Behavior|Foot Diseases
Interventions: BEHAVIORAL: Online leaflet about foot care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of Mometasone Furoate Delivered Via Concept1 Device or Twisthaler® Device in Adult and Adolescent Patients With Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Mometasone furoate|DEVICE: Concept 1|DEVICE: Twisthaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Different Modalities of Exercise in Patients With Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: OTHER: Experimental-Strength training|OTHER: Experimental-Aerobic training|OTHER: Experimental-Strength/Aerobic training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Efficacy of Mersina, an Ayurvedic Formulation: A Double Blind, Placebo Controlled Study in Type 2 Diabetic Patients With Secondary Failure to Oral Drugs
Status: COMPLETED
Conditions: Antihyperglycemic Effect in Type 2 Diabetic Patients With Secondary Failure to Oral Hypoglycemic Agents
Interventions: DRUG: Mersina
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Traditional Chinese Medicine (Qing-Re-Liang-Xue Decoction) as Complementary Medicine for Psoriasis Vulgaris of Blood-heat Syndrome.
Status: UNKNOWN
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Triamcinolone Acetonide Acetate and Urea Cream.|DRUG: Qing-Re-Liang-Xue Decoction.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Supplementation Combined With Endurance Training Improve Running Economy in Recreational Runners.
Status: COMPLETED
Conditions: Effect of Omega-3 Supplementation on Exercise Performance and Muscle Tissue Functions
Interventions: DIETARY_SUPPLEMENT: Omega-3 supplementation in recreational runners
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Intensive Social Interaction on Post-Stroke Depression in Individuals With Aphasia
Status: COMPLETED
Conditions: Post-stroke Depression|Post-stroke Aphasia
Interventions: BEHAVIORAL: Intensive communicative-pragmatic social interaction.|BEHAVIORAL: Standard care.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib/II Study of AK112 (PD-1/VEGF Bispecific Antibody) in Combination Therapy for Patients With Advanced Hepatocellular Carcinoma (HCC).
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: AK112|DRUG: Cadonilimab|DRUG: AK127|DRUG: AK130|DRUG: Sintilimab Injection|DRUG: Bevacizumab biosimilar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab, Paclitaxel, Carboplatin, and Radiation Therapy to the Chest in Treating Patients With Locally Advanced Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Adenocarcinoma of the Lung|Bronchoalveolar Cell Lung Cancer|Large Cell Lung Cancer|Stage II Non-small Cell Lung Cancer|Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer
Interventions: RADIATION: 3-dimensional conformal radiation therapy|DRUG: paclitaxel|BIOLOGICAL: bevacizumab|DRUG: carboplatin|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of 3 Different Auditory Applications on Newborn Heel Prick Procedure
Status: NOT_YET_RECRUITING
Conditions: Newborn Pain
Interventions: OTHER: mother lullaby group|OTHER: white noise group|OTHER: classical music group|OTHER: Contol Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trial to Confirm Safety & Effectiveness of the SYNERGY 4.50 mm and 5.00 mm Stent for Treatment of Atherosclerotic Lesion(s)
Status: COMPLETED
Conditions: Atherosclerosis|Heart Diseases, Coronary|Coronary Artery Disease|Cardiovascular Diseases
Interventions: DEVICE: SYNERGY 4.50 mm and 5.0 mm Coronary Stent System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection
Status: COMPLETED
Conditions: Appendicitis|Cholecystitis|Cross Infection|Diverticulitis|Peritonitis
Interventions: DRUG: tigecycline|DRUG: ceftriaxone sodium + metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Oncology Day Care Unit Programme With Two Different Focuses
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: Nature-near integrative day care unit programme|BEHAVIORAL: Conventional integrative day care unit programme
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Compare the Impact of a School Based HPV Program on Vaccination Uptake and Completion Rates
Status: COMPLETED
Conditions: Human Papillomavirus
Interventions: OTHER: HPV Vaccine and HPV-related Health Education|OTHER: Reduction of barriers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Study of Dexmedetomidine After Intra-Nasal and Buccal Dosing in Children
Status: COMPLETED
Conditions: Heart Diseases
Interventions: DRUG: Dexmedetomidine buccal|DRUG: Dexmedetomidine Intranasal|DRUG: Dexmedetomidine Intranasal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Two Different Heart-lung Machine Filling Methods: Precoating Versus Colloidal Fluids
Status: COMPLETED
Conditions: Priming|Cardiac Surgery|Cardio Pulmonary Bypass
Interventions: PROCEDURE: Precoating|PROCEDURE: Standard priming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-component Interventions to Increase HPV Vaccination in a Network of Pediatric Clinics
Status: COMPLETED
Conditions: Human Papillomavirus (HPV)
Interventions: BEHAVIORAL: Provider assessment and feedback|BEHAVIORAL: Provider reminders|BEHAVIORAL: Provider education|BEHAVIORAL: Patient reminders|BEHAVIORAL: Parent education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Floatation-REST and Anorexia Nervosa
Status: ACTIVE_NOT_RECRUITING
Conditions: Anorexia Nervosa
Interventions: BEHAVIORAL: Floatation-REST plus usual care|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Medical Device for Airway Patency During Sedation (SW01-2022)
Status: NOT_YET_RECRUITING
Conditions: Airway Obstruction|Sedation Complication|Safety Issues|Patient Satisfaction|Work Related Stress|Breathing Arrested|Complication of Treatment|Hypoxia
Interventions: DEVICE: Investigational device [I-IV]|DEVICE: Comparator [I-IV]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Study of Quinine Sulfate in Healthy Patients and in Patients With Renal Impairment
Status: TERMINATED
Conditions: Healthy|Renal Impairment
Interventions: DRUG: quinine sulfate|DRUG: quinine sulfate|DRUG: quinine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Eltrombopag and Recombinant Human Thrombopoietin In Primary Immune Thrombocytopenia
Status: UNKNOWN
Conditions: Corticosteroid-resistant or Relapsed ITP
Interventions: DRUG: Eltrombopag|DRUG: Recombinant human thrombopoietin (rh-TPO)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intravenous (IV) Iron vs. No Iron as the Treatment of Anemia in Cancer Patients Undergoing Chemotherapy and Erythropoietin Therapy
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: iron sucrose injection USP|DRUG: stable erythropoietin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: AIRB-4: Self-Determined Learning Model of Instruction
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Neurodevelopmental Disorders
Interventions: BEHAVIORAL: Self-Determined Learning Model of Instruction (SDLMI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Increased Intake of Low Fat Dairy Products on Weight Loss and Insulin Resistance
Status: COMPLETED
Conditions: Impaired Glucose Tolerance|Type 2 Diabetes|Metabolic Syndrome
Interventions: BEHAVIORAL: High dairy and calcium intake|BEHAVIORAL: Usual intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Hypervolt Device Application in the Treatment of Shoulder Impingement Syndrome
Status: COMPLETED
Conditions: Shoulder Impingement
Interventions: OTHER: Physiotherapy|OTHER: Hypervolt Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sunitinib in Metastatic Gastric Cancer
Status: COMPLETED
Conditions: Gastric Adenocarcinoma|Barrett Esophagus
Interventions: DRUG: Sunitinib-Malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Venetoclax or Lenalidomide in Combination With Ublituximab and Umbralisib in Subjects With Relapsed or Refractory CLL/SLL and NHL
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia|Non-Hodgkin Lymphoma
Interventions: DRUG: Venetoclax|DRUG: Umbralisib|BIOLOGICAL: Ublituximab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interventional Study to Evaluate the Appearance of Surgical Scars After Laser Therapy
Status: COMPLETED
Conditions: Cicatrix|Carbon Dioxide Laser
Interventions: DEVICE: Syneron-Candela CO2RE Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Relora Supplement on Anxiety, Cognitive Performance & Mood Tested After Induced Stress
Status: COMPLETED
Conditions: Mood (Psychological Function)
Interventions: DIETARY_SUPPLEMENT: Relora|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Omega 3 Supplementation and Ocular Surface Disease in Glaucoma
Status: WITHDRAWN
Conditions: Ocular Surface Disease
Interventions: DIETARY_SUPPLEMENT: Fishoil supplement|DIETARY_SUPPLEMENT: Olive Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Bay 59-8862 in Patients With Aggressive, Refractory Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: Taxane (Cytotoxic, BAY59-8862)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Physical and Mental Health of Older Patients With Newly Diagnosed Cancer
Status: COMPLETED
Conditions: Cognitive/Functional Effects|Depression|Hematopoietic/Lymphoid Cancer|Malnutrition|Pain|Psychosocial Effects of Cancer and Its Treatment|Unspecified Adult Solid Tumor, Protocol Specific|Weight Changes
Interventions: OTHER: medical chart review|OTHER: questionnaire administration|PROCEDURE: cognitive assessment|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Frovatriptan as a Transitional Therapy in Medication Overuse Headache
Status: COMPLETED
Conditions: Medication Overuse Headache|Analgesic Overuse Headache
Interventions: DRUG: Frovatriptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contrast-Enhanced Harmonic vs Conventional EUS-guided Fine Needle Biopsy for Solid Pancreatic Lesions: Randomized Controlled Trial
Status: UNKNOWN
Conditions: Pancreatic Solid Lesions
Interventions: DIAGNOSTIC_TEST: Endoscopic ultrasound-guided fine needle biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Investigate the Pharmacodynamic Effect After Four-week Omeprazole Treatment of Non-erosive Reflux Disease in a Japanese Population
Status: COMPLETED
Conditions: Non-erosive Reflux Disease
Interventions: DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to an HIV-1 DNA Vaccine (VRC HIVDNA009-00-VP) in HIV Uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: VRC-HIVDNA009-00-VP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Study of GDC-0575 Alone and in Combination With Gemcitabine in Participants With Refractory Solid Tumors or Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Solid Tumor
Interventions: DRUG: GDC-0575|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Project ECHO on Improving the Quality of Palliative Care in Patients With Advanced Cancer and Their Caregivers in Underserved Areas of Kenya, Nigeria, Ghana, South Africa, India, and Ethiopia
Status: RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Hematopoietic and Lymphoid Cell Neoplasm
Interventions: OTHER: Extension of Community Health (ECHO) Telementoring Clinic|OTHER: In-Country Workshops|OTHER: Professional Oncology Educations Programs|OTHER: Medical Chart Review|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I, Escalating, Multiple-Dose, ST-246 Safety, Tolerability and Pharmacokinetics 21-Day Trial in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ST-246|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Possible Protective Effect of Celecoxib Against Capecitabine Induced Hand and Foot Syndrome in Patients With Colorectal Cancer
Status: RECRUITING
Conditions: Hand and Foot Syndrome|Erythrodysesthesia Syndrome|HFS|Colorectal Cancer
Interventions: DRUG: Celecoxib 200mg|DRUG: Capecitabine-based chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Second-line Treatment of Postoperative Recurrence and Metastasis of Esophageal Cancer Treated With Apatinib
Status: WITHDRAWN
Conditions: Esophageal Neoplasms
Interventions: DRUG: Apatinib|DRUG: The chemotherapeutic drug chosen by the investigator.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on the Head (Face or Scalp)
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: PEP005 (Ingenol Mebutate) gel, 0.015%|DRUG: Vehicle Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-detector Computer Tomography Protocol Project: Chest Imaging Technique and Case Presentation
Status: COMPLETED
Conditions: Aortic Dissection|Thrombosis in Left Atrium and Right Axillary Artery|Double IVC|May-Thurner Syndrome|Pulmonary Thromboembolism
Interventions: OTHER: Chest imaging technique and case presentation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Milk-Only Lactation Study to Evaluate the Concentration of Bempedoic Acid and Bempedoic Acid/Ezetimibe Fixed Combination Drug Product (FCDP) in the Breast Milk of Healthy Lactating Women
Status: COMPLETED
Conditions: Healthy Lactating Women
Interventions: DRUG: Bempedoic Acid 180 MG Oral Tablet|DRUG: Bempedoic Acid/Ezetimibe 180 MG-10 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fixed Dose Combination of Fluoxetin and Metformin in the Management of Overweight and Obesity
Status: SUSPENDED
Conditions: Overweight and Obesity
Interventions: DRUG: combination metformin hydrochloride/ fluoxetine 500/20 mg|DRUG: combination metformin hydrochloride/ fluoxetine 1000/20mg|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical Cohort Study - TRUST
Status: RECRUITING
Conditions: Arrhythmias, Cardiac|Atrial Fibrillation|Atrial Flutter|Ventricular Tachycardia|Atrial Tachycardia|Arrhythmogenic Right Ventricular Dysplasia|Long QT Syndrome|Brugada Syndrome|Supraventricular Tachycardia|Catecholaminergic Polymorphic Ventricular Tachycardia|Torsades de Pointes|Atrial Cardiomyopathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Durvalumab and Tremelimumab as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab (Regimen 1)|DRUG: Tremelimumab (Regimen 2)|DRUG: Sorafenib|DRUG: Durvalumab (Regimen 1)|DRUG: Durvalumab (Regimen 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Slipped Capital Femoral Epiphysis (SCFE) on Top of Fixed Fracture Neck of Femur Case Report.
Status: COMPLETED
Conditions: Slipped Capital Femoral Epiphysis
Interventions: PROCEDURE: subtrochanteric valgus osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Ultrasound Analysis of Two Hyaluronic Acid Dermal Fillers
Status: COMPLETED
Conditions: Volume Deficiency of the Midface
Interventions: DEVICE: Restylane Contour|DEVICE: Juvederm Voluma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dietary Factors and Disfluency: A Look Into Food Allergies and Other Environmental Triggers Associated With Variations in Severity of Vocal Cord Tension.
Status: UNKNOWN
Conditions: Vocal Cord Tension|Dysfluency Developmental
Interventions: OTHER: Food Allergy Testing and Elimination Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ishige Okamurae Extract on Musculoskeletal Biomarkers in Adults With Relative Sarcopenia
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Ishige Okamurae extracts group|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pragmatic Approach to Lowering the Risk of Diabetes Mellitus After A Diagnosis of Gestational Diabetes Mellitus
Status: UNKNOWN
Conditions: Gestational Diabetes
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Epinephrine on Post-polypectomy Pain
Status: COMPLETED
Conditions: Colonic Polyp
Interventions: DRUG: Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Effects of Cosmeceutical Therapy in Subjects Undergoing Full Facial Rejuvenation
Status: COMPLETED
Conditions: Facial Rejuvenation With Neurotoxins and/or Hyaluronic Acid Fillers
Interventions: OTHER: Basic Skin Care|OTHER: Active Skin Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Phase 2 Study to Evaluate the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of VX-135 and Daclatasvir in Subjects With Genotype 1 Chronic Hepatitis C Chronic Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C|CHC|HCV|Hepatitis C
Interventions: DRUG: VX-135|DRUG: Daclatasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of Emapalumab in Primary Haemophagocytic Lymphohistiocytosis
Status: COMPLETED
Conditions: Primary Hemophagocytic Lymphohistiocytosis
Interventions: DRUG: Emapalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics/Pharmacodynamics (PK/PD) Equivalence Study of MSB11456
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: MSB11456|DRUG: US-licensed Actemra|DRUG: EU-approved RoActemra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Epratuzumab in Serologically-positive Systemic Lupus Erythematosus (SLE) Patients With Active Disease
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Epratuzumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Pressure and Lipids Reduction in High Risk Elderly Patients With Isolated Systolic Hypertension
Status: RECRUITING
Conditions: Isolated Systolic Hypertension
Interventions: DRUG: Amlodipine/Atorvastatin 5 Mg-10 Mg ORAL TABLET|DRUG: Amlodipine 5mg|OTHER: Lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effectiveness of Two Produce Prescription Approaches On Fruit and Vegetable Intake and Food Security, While Exploring Implementation Outcomes Such as Reach, Implementation, Sustainability, and Cost
Status: RECRUITING
Conditions: Food Insecurity
Interventions: OTHER: Product prescription program- NutriConnect Credit|OTHER: Product prescription program- NutriConnect Delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Evaluate the Efficacy, Safety, and Tolerability of Topical VDA-1102 Ointment in Subjects With Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: 10% VDA-1102|DRUG: 20% VDA-1102
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: WI-INTUIT: Bridging Community Based Continence Promotion and Primary Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Urinary Incontinence
Interventions: BEHAVIORAL: UI-Assist|OTHER: Partnership Building
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Music Therapy or Book Discussion in Improving Quality of Life in Young Patients Undergoing Stem Cell Transplant
Status: COMPLETED
Conditions: Malignant Neoplasm
Interventions: PROCEDURE: Music Therapy|PROCEDURE: Psychosocial Assessment and Care|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Fruquintinib in Combination With PD-1 Inhibitors as First-line Maintenance Therapy for Advanced HER-2 Negative Gastric Cancer: a Single-arm, Prospective, Exploratory Clinical Study
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Fruquintinib+PD-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Injection of Autologous Adipose-derived Stromal Vascular Fraction in the Finger of Systemic Sclerosis Patients
Status: COMPLETED
Conditions: Systemic Sclerosis
Interventions: PROCEDURE: SVF injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Cord Stimulation for Pain Relief in Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Constipation|Diarrhea|Pain
Interventions: DEVICE: Spinal Cord Stimultion (SCS)|DEVICE: Spinal cord nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: GentleCath™ for Men Intermittent Catheter With FeelClean™ Technology
Status: COMPLETED
Conditions: Bladder Outlet Obstruction|Multiple Sclerosis|Cauda Equina Syndrome|Enlarged Prostate With Lower Urinary Tract Symptoms|Parkinson Disease|Lower Urinary Tract Symptoms|Detrusor Underactivity|Spinal Cord Injuries
Interventions: DEVICE: Intermittent self-catheterisation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Abemaciclib (LY2835219) in Participants With Non-Small Cell Lung Cancer or Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer|Breast Cancer
Interventions: DRUG: Abemaciclib|DRUG: Pembrolizumab|DRUG: Anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pyrotinib Maleate, Trastuzumab, SHR6390 and Letrozole in Combination for Stage II-III TPBC
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Pyrotinib maleate, dalpiciclib, Trastuzumab, letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Clinical Performance of a Novel Multipurpose Solution
Status: COMPLETED
Conditions: Ocular Discomfort
Interventions: DEVICE: Bausch & Lomb Multi-Purpose Solution|DEVICE: Ciba's Multi-Purpose Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mast Cells in Acid-induced Intestinal Permeability
Status: TERMINATED
Conditions: Dyspepsia
Interventions: DRUG: Nalcrom|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: AppReminders - A Pilot Feasibility Trial of a Memory Aid App for People With Acquired Brain Injury
Status: RECRUITING
Conditions: Acquired Brain Injury
Interventions: DEVICE: ApplTree|DEVICE: Google Calendar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Care at 360º: A Long-term Individual Cognitive Stimulation Program
Status: COMPLETED
Conditions: Neurocognitive Disorders|Dementia|Cognitive Impairment|Cognitive Decline|Cognitive Dysfunction|Social Behavior
Interventions: BEHAVIORAL: Cognitive Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of follow-on Formula Enriched on Short-chain Fructooligosaccharides (scFOS) on Immune Response in Healthy Infants
Status: COMPLETED
Conditions: Infant
Interventions: DIETARY_SUPPLEMENT: Follow-on formula supplemented with fructo-oligosaccharides|DIETARY_SUPPLEMENT: Follow-on formula enriched with placebo (maltodextrins)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: