pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Achieving Portal Access With Scorpion Post-Approval Study (APASS)
Status: TERMINATED
Conditions: Portal Hypertension|Liver Diseases|Ascites Hepatic|Hydrothorax|Vascular Diseases
Interventions: DEVICE: Scorpion Portal Vein Access Kit|DEVICE: Cook Transjugular Liver Access Set|PROCEDURE: Transjugular Intrahepatic Portosystemic Shunt (TIPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics/Pharmacodynamics (PK/PD) of Multiple Oral Doses of GLPG0555 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG0555|DRUG: GLPG0555 aqueous|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study to Investigate the Interaction Between Givosiran and a 5-probe Drug Cocktail in Patients With Acute Intermittent Porphyria (AIP)
Status: COMPLETED
Conditions: Acute Intermittent Porphyria (AIP)|Acute Hepatic Porphyria (AHP)|Porphyria, Acute Intermittent|Acute Porphyria
Interventions: DRUG: Givosiran|DRUG: 5-probe cocktail
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAncer, NUtrition and Taste - Validation of the CANUT-QVA Questionnaire on Eating Habits in Cancer Patients
Status: COMPLETED
Conditions: Hematologic Cancer|Undernutrition|Chemotherapy Effect|Taste Disorders|Chemotherapy-Induced Change|Olfactory Disorder
Interventions: OTHER: Evaluation of the 9 dimensions of the CANUT-QVA questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Relationship Between Vitamins and Radiologic Stage in Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DIAGNOSTIC_TEST: Direct digital radiography|DIAGNOSTIC_TEST: 25-OH Vitamin D|DIAGNOSTIC_TEST: Vitamin B12|DIAGNOSTIC_TEST: Folic acid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Real World Evidence With the Debritom+ TM Novel Micro Water Jet Technology at a Single Wound Center
Status: RECRUITING
Conditions: Diabetic Foot Ulcer|Venous Leg Ulcer|Surgical Wound Dehiscence|Traumatic Wounds
Interventions: DEVICE: Study Device Debridement|DEVICE: SOC Debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DOTS: Dalbavancin as an Option for Treatment of Staphylococcus Aureus Bacteremia
Status: COMPLETED
Conditions: Staphylococcal Bacteraemia
Interventions: DRUG: Cefazolin|DRUG: Dalbavancin|DRUG: Daptomycin|DRUG: Nafcillin|DRUG: Oxacillin|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Acetaminophen Plus Tramadol Hydrochloride (JNS013) in Participants With Chronic Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Tramadol Hydrochloride Plus Acetaminophen (Open-Label)|DRUG: Tramadol Hydrochloride Plus Acetaminophen (Double-Blind)|DRUG: Placebo (Double-Blind)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EFFECT OF ADDING DAPAGLIFLOZIN TO ALLOGRAFT DYSFUNCTION OF RENAL TRANSPLANTED PATIENTS.
Status: COMPLETED
Conditions: Kidney Transplantation|Diabetes Mellitus, Type 2|Diabetes Complications
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Home-Based Walking Program on Peripheral Neuropathy, Fatigue and Quality of Life
Status: RECRUITING
Conditions: Chemotherapeutic Toxicity
Interventions: OTHER: Home Based Walking Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Behavioral Pharmacology of THC and D-limonene
Status: COMPLETED
Conditions: D-limonene and THC Pharmacodynamics
Interventions: DRUG: Placebo|DRUG: Vaporized THC, limonene, or THC and limonene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing Pain Outcomes of Treatment Strategies for Osteoarthritis Knee Patients
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee|Pain
Interventions: DEVICE: Cooled Radiofrequency Ablation|DEVICE: Hyaluronic Acid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Octreotide Capsules (MYCAPSSA) in Acromegaly
Status: UNKNOWN
Conditions: Acromegaly
Interventions: DRUG: octreotide capsules|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Investigate Markers Of Inflammation In Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Osteoarthritis
Interventions: PROCEDURE: Power doppler ultrasonography|PROCEDURE: High frequency ultrasonography|PROCEDURE: Exhaled nitric oxide assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Androgen Deprivation Therapy (ADT) and Pembrolizumab for Advanced Stage Androgen Receptor-positive Salivary Gland Carcinoma
Status: RECRUITING
Conditions: Salivary Gland Carcinoma
Interventions: DRUG: Goserelin Acetate|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment for Persistently Fatigued Cancer Survivors: A Randomized Controlled Trial With Biomarker Response
Status: COMPLETED
Conditions: Fatigue
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction|BEHAVIORAL: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Bilateral Erector Spinae Plan Block in Colorectal Surgery
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Erector spina plane block + general anesthesia|PROCEDURE: Only general anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Trial of MP0250 Plus Bortezomib + Dexamethasone in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma in Relapse
Interventions: BIOLOGICAL: MP0250 plus BOR+DEX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monosialoganglioside Ganglioside in Cerebral Radiation Necrosis
Status: UNKNOWN
Conditions: Cerebral Radiation Necrosis
Interventions: DRUG: Monosialoganglioside Ganglioside|DRUG: Methylprednisolone (Steroid Hormone)|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of the Biologic Lung Volume Reduction (BLVR) System in Advanced Upper Lobe Predominant (ULP) Emphysema
Status: WITHDRAWN
Conditions: Advanced Upper Lobe Predominant Emphysema
Interventions: DRUG: BLVR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind, Placebo-controlled, Combined Single Ascending Dose and Multiple Ascending Dose Study
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Active Comparator: A|DRUG: Placebo Comparator B|DRUG: Active Comparator B|DRUG: Placebo Comparator A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of iPelvis App for Female Pelvic Floor Dysfunction
Status: COMPLETED
Conditions: Female Sexual Dysfunction|Urinary Incontinence
Interventions: OTHER: Home Exercise Sheet|OTHER: Ipelvis mobile application|BEHAVIORAL: Home exercise sheet + Pelvic Physiotherapy|BEHAVIORAL: Ipelvis mobile application + Pelvic Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Allergen Reduction and Child Health Study (ARCHS)
Status: RECRUITING
Conditions: Asthma in Children
Interventions: BEHAVIORAL: Comparator 1 (tailored approach)|BEHAVIORAL: Comparator 2 (insecticidal bait)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dapagliflozin on Glycemic Variability
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating Lu AG22515 in Healthy Adults
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Lu AG22515|DRUG: Placebo|DRUG: Immune System Activator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing Preoperative Short-course Radiotherapy With or Without Local Boost for Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: RADIATION: preoperative short-course radiotherapy with local boost|RADIATION: preoperative short-course radiotherapy without local boost|PROCEDURE: TME surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Chemotherapy Based on the Adenosine Triphosphate Tumor Chemosensitivity Assay for Hepatocellular Carcinoma After Liver Transplantation
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Individualized Chemotherapy|DRUG: mFOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Combined With Yangzhengxiaoji Capsule in Patients With Advanced Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Yangzhengxiaoji Capsule|DRUG: Placebo Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Beginning of Effective and Safe Treatment in Immunoglobulin A-1 Nephropathy-1
Status: UNKNOWN
Conditions: Glomerulonephritis, Immunoglobulin A (IgA)
Interventions: DRUG: Losartan group|DRUG: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PINTA - Prophylactic Incisional Negative Pressure Therapy for Major Amputations
Status: NOT_YET_RECRUITING
Conditions: Wound Surgical|Wound Infection|Cosmesis
Interventions: DEVICE: Negative Pressure Wound Therapy|DEVICE: Standard Wound Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome of the Semibranch in Pararenal and Thoracoabdominal Aortic Pathologies. A Prospective, Multicentre Registry.
Status: RECRUITING
Conditions: Aortic Aneurysm|Endovascular Aortic Repair|Stent-Graft Endoleak
Interventions: DEVICE: Semibranch CMD branched aortic stentgraft
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cholinergic Mechanisms of Attentional-motor Integration and Gait Dysfunction in Parkinson Disease (UDALL)
Status: RECRUITING
Conditions: Parkinson Disease|Progressive Supranuclear Palsy
Interventions: RADIATION: (18)F]fluoroethoxybenzovesamicol ([(18)F (FEOBV) PET|RADIATION: Dihydrotetrabenazine (DTBZ) PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Post-licensure, Modified Double-blind, Multi-center Study Evaluating Safety and Immunogenicity of ADACEL® and BOOSTRIX®
Status: COMPLETED
Conditions: Pertussis|Tetanus|Diphtheria
Interventions: BIOLOGICAL: ADACEL®:Tetanus, Reduced Diphtheria and Acellular Pertussis Adsorbed|BIOLOGICAL: BOOSTRIX®: Tetanus, Reduced Diphtheria and Acellular Pertussis Adsorbed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Exploratory Safety Study to Investigate the Extent of Tumor Cell Mobilization (TCM) After Use of G-CSF Alone or G-CSF Plus Plerixafor in Multiple Myeloma (MM) Patients Who May be Poor Mobilizers of Stem Cells
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Plerixafor|DRUG: Granulocyte-colony stimulating factor (G-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotinamide Riboside for Diabetic Neuropathy
Status: SUSPENDED
Conditions: Diabetic Neuropathy Peripheral
Interventions: DRUG: Niagen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Yoga and Gentle Massage Practices on Symptom Management in Patients Undergoing HSCT
Status: RECRUITING
Conditions: Hematopoietic Stem Cell Transplantation|Bone Marrow Transplantation
Interventions: BEHAVIORAL: yoga or gentle massage plus standard treatment for HSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nicotine TMS EFT Smoking Pilot Study
Status: COMPLETED
Conditions: Smoking|Nicotine Dependence|Addiction|Smoking, Cigarette
Interventions: DEVICE: Real cTBS|DEVICE: Sham cTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Changes of Ascending Aortic Diameter in Patients Undergoing Transcatheter Aortic Valve Replacement
Status: RECRUITING
Conditions: Aortic Stenosis|Ascending Aortic Dilatation|Bicuspid Aortic Valve
Interventions: PROCEDURE: Transcatheter aortic valve replacement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of the External Synchronized Vein Valve (ESVV) in Treatment of Chronic Venous Insufficiency (CVI)
Status: UNKNOWN
Conditions: Venous Insufficiency
Interventions: DEVICE: ESVV device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physician-Sponsored IDE for Talent Endoluminal Spring Graft System in Patients With Abdominal Aortic Aneurysms (AAA)
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysms
Interventions: DEVICE: Talent Endoluminal Spring Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulation of Regional Brain Activation in Schizophrenic Patients by Pharmacological Therapy
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Amisulpride|DRUG: Olanzapine|DRUG: Haloperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Crossover Study to Compare the Pharmacokinetics and Bioavailability of a Novel Furosemide Regimen Administered Subcutaneously vs. the Same Dose Administered Intravenously in Subjects With Chronic Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Furosemide Injection Solution for subcutaneous administration (80 mg)|DRUG: Furosemide Injection, USP|DEVICE: Medfusion 3500 (v6) precision infusion pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and Ipilimumab in People With Aggressive Pituitary Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Pituitary|Pituitary Tumor|Pituitary Carcinoma|Pituitary Cancer
Interventions: DRUG: Ipilimumab|DRUG: Nivolumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Kaltenborn Versus Mulligan Techniques in Rheumatoid Arthritis.
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Kaltenborn|OTHER: Mulligan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Eplerenone on the Evolution of Vasculopathy in Renal Transplant Patients.
Status: RECRUITING
Conditions: Kidney Transplantation for More Than One Year|Patients With a Kidney Transplantation on Cyclosporine
Interventions: DRUG: Eplerenone 50mg/day (cross over design)|OTHER: Period without eplerenone (cross over design)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eribulin Mesylate and Gemcitabine Hydrochloride in Treating Patients With Metastatic Solid Tumors or Solid Tumors That Cannot be Removed by Surgery
Status: COMPLETED
Conditions: Adult Solid Neoplasm|Recurrent Ovarian Carcinoma|Recurrent Uterine Corpus Carcinoma|Stage III Ovarian Cancer AJCC v6 and v7|Stage III Uterine Corpus Cancer AJCC v7|Stage IV Ovarian Cancer AJCC v6 and v7|Stage IV Uterine Corpus Cancer AJCC v7
Interventions: DRUG: Eribulin Mesylate|DRUG: Gemcitabine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Cholecystectomy in Management of ACC Within Versus After 3 Days
Status: COMPLETED
Conditions: Acute Calculous Cholecystitis
Interventions: PROCEDURE: Laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of an Investigational Medication for the Treatment of Secondary Hyperparathyroidism in Patients on Dialysis
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism|End Stage Renal Disease
Interventions: DRUG: Placebo|DRUG: AMG 073
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GI-101 as a Single Agent or in Combination With Pembrolizumab, Lenvatinib or Local Radiotherapy in Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|Metastatic Solid Tumor|Non-small Cell Lung Cancer|Head and Neck Squamous Cell Carcinoma|Renal Cell Carcinoma|Urinary Bladder Cancer|Melanoma|Sarcoma|Microsatellite Stable Colorectal Carcinoma|Merkel Cell Carcinoma|Esophageal Squamous Cell Carcinoma|Cervical Cancer|Vaginal Cancer|Vulvar Cancer
Interventions: DRUG: GI-101|DRUG: Pembrolizumab (KEYTRUDA®)|DRUG: Lenvatinib|RADIATION: Local Radiotherapy|DRUG: GI-101A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Methylphenidate Hydrochloride to Reduce Fatigue in Prostate Cancer Patients Receiving Hormone Therapy
Status: TERMINATED
Conditions: Prostatic Neoplasms|Fatigue
Interventions: DRUG: Methylphenidate Hydrochloride|DRUG: Matched Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Proof-of-concept Study of the Efficacy and Safety of Nipocalimab in Participants With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: OTHER: Placebo|DRUG: Nipocalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Arousal Threshold in Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Donepezil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Home Care Medication Management Program for the Frail Elderly
Status: COMPLETED
Conditions: Chronic Illness|Cognitive Impairment
Interventions: OTHER: MD2 machine and nurse care coordination|OTHER: Medplanner and Nurse Care Coordination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate a Range of Dose Levels and Vaccination Intervals of Ad26.COV2.S in Healthy Adults and Adolescents
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Ad26.COV2.S|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of Audiovisual Distraction Behavior Guidance Technique in Children With Dental Anxiety
Status: COMPLETED
Conditions: Dental Anxiety|Dental Pain and Sensation Disorder
Interventions: DEVICE: Virtual Reality Device|DEVICE: Protective glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Prevalence of Homologous Recombination Deficiency Among Women With Newly Diagnosed, High-grade, Serous or Endometrioid Ovarian, Primary Peritoneal, and/or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of MK0653A (Ezetimibe (+) Simvastatin) in Patients With Hypercholesterolemia (0653A-038)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: MK0653A, ezetimibe (+) simvastatin|DRUG: Comparators: simvastatin and ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Disease Characteristics, Treatment Patterns and Clinical Outcomes in Patients With Newly Diagnosed Unresectable Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) in China
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer, Lung Cancer, Cancer
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Applying Pulsed Radiofrequency to the Pudendal Nerve Bilaterally Vs Its Application to Sacral Nerve Roots S2,3 and 4 Bilaterally in Chronic Prostatitis
Status: UNKNOWN
Conditions: Prostatitis|Pulsed Radiofrequency
Interventions: RADIATION: pudendal nerve|RADIATION: sacral n roots
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety of the Drugs Topiramate and Levetiracetam in Treating Children Recently Diagnosed With Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Topiramate|DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Boosting Emotional Well-being and Happiness in Outpatients Living With Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Positive Psychology + Motivational Interviewing|BEHAVIORAL: Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Vaginal Lactobacilli and Estriol (Gynoflor®) for Atrophic Vaginitis in Breast Cancer Patients
Status: COMPLETED
Conditions: Atrophic Vaginitis
Interventions: DRUG: Gynoflor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retrospective Assessment of the Risk of Peripartum Hemorrhage in Pregnant Women : Retrospective Assessment of the Diagnostic Performance of the HEMSTOP Standardized Questionnaire
Status: COMPLETED
Conditions: Peripartum Period|Hemorrhage|HEMSTOP Questionnaire
Interventions: DIAGNOSTIC_TEST: HEMSTOP questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG)
Status: RECRUITING
Conditions: Myasthenia Gravis, Generalized
Interventions: DRUG: Descartes-08
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Pharmacokinetics and Target Engagement of BMS-986142 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Adult
Interventions: DRUG: BMS-986142|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Noninvasive Arterial Input Estimation Method for O-15 PET and Integrated PET/MR Scanning
Status: WITHDRAWN
Conditions: Validation of a New Noninvasive Method to Obtain the Arterial Input Function (AIF) Directly by PET Imaging
Interventions: DRUG: [O-15]Water|DRUG: Acetazolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: High or Standard Intensity Radiation Therapy After Gemcitabine Hydrochloride and Nab-paclitaxel in Treating Patients With Pancreatic Cancer That Cannot Be Removed by Surgery
Status: TERMINATED
Conditions: Pancreatic Adenocarcinoma|Stage III Pancreatic Cancer
Interventions: RADIATION: low intensity radiation therapy|DRUG: Capecitabine|DRUG: Gemcitabine|RADIATION: high intensity radiation therapy|DRUG: nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Therapy in HIV-1 Infected Patients With Successful Viral Suppression Under Highly Active Antiretroviral Therapy (HAART)
Status: TERMINATED
Conditions: HIV Infections
Interventions: PROCEDURE: Intermittent antiretroviral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Penetration of Moxifloxacin Into Liver Tissue of Patients Undergoing Liver Resection.
Status: COMPLETED
Conditions: Side-effect of Antibiotic
Interventions: DRUG: Moxifloxacin 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reversibility of Dual Antiplatelet Therapy by Platelets
Status: COMPLETED
Conditions: Bleeding
Interventions: OTHER: autologous stored platelets|OTHER: administration of autologous stored platelets|BIOLOGICAL: autologous stored platelets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of ELND002 in Patients With Relapsing Forms of Multiple Sclerosis
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: DRUG: ELND002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Humanized CD19 Chimeric Antigen Receptor (CAR)-Modified T Cell Therapy in Treating Patients With B-cell Malignancies
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia|B Cell Lymphoma
Interventions: GENETIC: Second generation humanized CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Biphasic Insulin Compared to Biphasic Insulin Combined With Insulin Aspart, With or Without Metformin in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of KCT-0809 in Patients With Dry Eye Syndromes
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: KCT-0809|DRUG: KCT-0809|DRUG: KCT-0809|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of a Single-Use, Point-of-Care Molecular Diagnostic Device for the Detection of Neisseria Gonorrhoeae (NG), Trichomonas Vaginalis (TV), and Chlamydia Trachomatis (CT) Utilizing Vaginal Swabs
Status: TERMINATED
Conditions: Chlamydial Infection|Gonorrhoea|Trichomoniasis
Interventions: DEVICE: Click Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Family Empathic Behaviour Versus Nurse Empathic Behaviour
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: BEHAVIORAL: Empathic behaviour by nurses.|BEHAVIORAL: Empathic behaviour by family.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study to Characterize the Pharmacokinetics of Raltegravir in the Gastrointestinal (GI) Tract of Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Different Regimen of Aprotinine(Trasylol) Administration in Patients Receiving Antiplatelet Therapy With Clopidogrel (Plavix)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Aprotinine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Safety/Efficacy of Test Article in Patients With Interdigital T. Pedis
Status: TERMINATED
Conditions: Interdigital Tinea Pedis
Interventions: DRUG: Cohort 1 J. Lividum|OTHER: Placebo Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Based Tele-Exercises on Exercise Capacity in Cystic Fibrosis
Status: RECRUITING
Conditions: Cystic Fibrosis in Children|Telerehabilitation|Virtual Reality
Interventions: OTHER: Virtual reality|OTHER: Online
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acupressure on Patients Receiving Brachytherapy
Status: ENROLLING_BY_INVITATION
Conditions: Brachytherapy|Complementary Approaches|Gynecological Cancers
Interventions: OTHER: The group to which Acupressure will be applied in each fraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Troponin in Acute Chest Pain to Risk Stratify and Guide EffecTive Use of Computed Tomography Coronary Angiography
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: RADIATION: CT Coronary Angiography (CTCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Expanded Access Study of Melphalan With Delcath CS-PHP System in Patients With Ocular/Cutaneous Melanoma Mets to Liver
Status: NO_LONGER_AVAILABLE
Conditions: Metastatic Liver Cancer|Ocular Melanoma|Cutaneous Melanoma
Interventions: DRUG: Melphalan|DEVICE: Percutaneous Hepatic Perfusion
Study Type: EXPANDED_ACCESS
Clinical trial: Effectiveness of Endoscopic Sleeve Gastroplasty in Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis
Status: RECRUITING
Conditions: Nonalcoholic Fatty Liver Disease
Interventions: PROCEDURE: Endoscopic Sleeve Gastroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy
Status: RECRUITING
Conditions: Breast Cancer, Early Breast Cancer
Interventions: DRUG: Camizestrant|DRUG: Tamoxifen|DRUG: Anastrozole|DRUG: Letrozole|DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aerobic Exercise for Older Adults at Increased Risk of Alzheimer's Disease and Related Dementias
Status: RECRUITING
Conditions: Alzheimer Disease|Dementia
Interventions: BEHAVIORAL: Aerobic exercise|BEHAVIORAL: Stretch and Strength
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Polyphenol-rich Dark Chocolate on Obesity
Status: UNKNOWN
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: placebo|DIETARY_SUPPLEMENT: Acticoa polyphenol-rich dark chocolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients With Relapsed or Refractory Breast, Colorectal and Non-Small Cell Lung Cancer (0683-011)(TERMINATED)
Status: TERMINATED
Conditions: Breast Cancer|Colorectal Cancer|Non-small-cell Lung Carcinoma
Interventions: DRUG: MK0683, vorinostat, Suberoylanilide Hydroxamic Acid (SAHA)|DRUG: Duration of Treatment - During each treatment cycle, treatment is administered twice daily for 14 days, followed by 7 days of rest for a total of 10 cycles
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pathogenicity of B and CD4 T Cell Subsets in Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis|Clinically Isolated Syndrome
Interventions: BIOLOGICAL: blood sample|BIOLOGICAL: cerebro-spinal fluid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase I Feasibility Study of an Intraprostatic PSA-Based Vaccine in Men With Prostate Cancer With Local Failure Following Radiotherapy or Cryotherapy or Clinical Progression on Androgen Deprivation Therapy in the Absence of Local Definitive Therapy
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Recombinant Vaccinia-PSA(L155)/TRICOM (PROSTVAC-V/TRICOM)|DRUG: Recombinant Fowlpox-PSA(L155)/TRICOM (PROSTVAC-F/TRICOM)|DRUG: Recombinant Fowlpox-GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of Lenalidomide in Combination With Gemcitabine in Patients With Untreated Advanced Carcinoma of the Pancreas
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: CC-5013|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Behavioral Parent Training for Childhood ADHD: A Micro-randomized Trial
Status: RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Mobile behavioral parent training (mBPT) and prompts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Extension of Oral Treprostinil in Subjects With PH Associated With HFpEF
Status: TERMINATED
Conditions: Pulmonary Hypertension Associated With HFpEF
Interventions: DRUG: Oral treprostinil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Pharmacokinetics and Safety Between BR9004 and BR9004-1 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: BR9004|DRUG: BR9004-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Video Laryngoscope vs. Video Stylet During General Anesthesia With Obesity Patient
Status: UNKNOWN
Conditions: Intubation; Difficult or Failed|Obesity
Interventions: DEVICE: McGrath MAC|DEVICE: Trachway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intra-articular Morphine and Clonidine Injections for Pain Management in Hip Arthroscopy
Status: COMPLETED
Conditions: Femoracetabular Impingement|Pain, Postoperative
Interventions: DRUG: Morphine with clonidine|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Hormonal Add-Back Therapy in Adolescents Treated With a GnRH Agonist for Endometriosis: A Randomized Trial
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Norethindrone acetate + estrogens|DRUG: norethindrone acetate + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Working Toward the Advancement of Recovery Using Modulated Therapeutic Hyperthermia (WARMTH) in Sepsis - Pilot
Status: WITHDRAWN
Conditions: Sepsis
Interventions: OTHER: Multimodal therapeutic warming w/ esophageal d/c|OTHER: Multimodal therapeutic warming w/ conductive d/c
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 4'-Thio-araC (Thiarabine) in Advanced Hematologic Malignancies
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: 3 Day Thiarabine|DRUG: 5 Day Thiarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Informative Intervention to the ICU Team About the Presence of Asynchronies in Mechanically Ventilated Patients: Effect Over Incidence Reduction
Status: COMPLETED
Conditions: Asynchronies
Interventions: BEHAVIORAL: Daily asynchronies information
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Value Of ACE Index (Albumin, CRP And Endoscopy) In Predicting Intra Venous Steroid Response In Acute Severe Ulcerative Colitis In Assiut University Hospitals
Status: NOT_YET_RECRUITING
Conditions: Early Detection of Complication of Ulcerative Colitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oxaliplatin in Combination With Capecitabine and Concurrent Radiation Therapy in Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-Small Cell Lung
Interventions: DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Diagnosis and Pathological Spectrum of Porto-sinusoidal Vascular Disease in India
Status: RECRUITING
Conditions: Portal Hypertension|Budd-Chiari Syndrome|Non-Cirrhotic Portal Hypertension|Porto-Sinusoidal Vascular Diseases|Sinusoidal Obstruction Syndrome|Veno Occlusive Disease, Hepatic|Non-Cirrhotic Portal Fibrosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Promoting Genetic Counseling Among African American Women With a Family History of Breast Cancer
Status: RECRUITING
Conditions: High Risk for Breast Cancer
Interventions: BEHAVIORAL: Decision aid video|BEHAVIORAL: Genetic counseling informational brochure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Immunological Memory Induced by the 13valent Pneumococcal Conjugate(PCV13) and 23valent Plain Polysaccharide Vaccine(PPV23) in HIV-infected Patients
Status: UNKNOWN
Conditions: HIV Infection
Interventions: BIOLOGICAL: PCV13|BIOLOGICAL: PPV23
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 1 Study to Compare CMAB807 Injection to Prolia® in Healthy Volunteers
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Prolia®|DRUG: CMAB807
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-Angle Glaucoma or Ocular Hypertension Patients
Status: COMPLETED
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Travoprost 0.004% with and without BAK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Antidepressant Effects of rTMS After Ischemic Stroke
Status: UNKNOWN
Conditions: Post-stroke Depression
Interventions: DEVICE: active rTMS treatment|DEVICE: sham rTMS treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of SCY-078 (Ibrexafungerp) on the PK of Pravastatin in Healthy Subjects
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: PRA|DRUG: SCY-078 plus PRA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pilot Study on Withdrawal of Spironolactone Among Heart Failure With Improved Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Withdrawal of Spironolactone|DRUG: Continuation of spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Ex-vivo Normothermic Machine Perfusion With the Organox Metra™ Device to Store Human Livers for Transplantation
Status: UNKNOWN
Conditions: End-stage Liver Disease
Interventions: DEVICE: OrganOx Metra
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Botulinum Toxin A for the Treatment of Keratoconus
Status: COMPLETED
Conditions: Keratoconus
Interventions: PROCEDURE: Subcutaneous injection of botulinum toxin type A|DRUG: Botulinum Toxin Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selinexor, Anti-PD-1 Antibody and P-GemOx Regimen in R/R NKTCL
Status: NOT_YET_RECRUITING
Conditions: Lymphoma
Interventions: DRUG: Selinexor, anti-PD-1 antibody and P-GemOx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effect on Central Retinal Thickness of BI 1026706 in Patients With Diabetic Macular Edema
Status: COMPLETED
Conditions: Macular Edema
Interventions: DRUG: BI 1026706|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Rosuvastatin and Lopinavir/Ritonavir in HIV Patients
Status: COMPLETED
Conditions: HIV Infections|Hyperlipidemia
Interventions: DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Thalidomide, Celecoxib, Etoposide and Cyclophosphamide in Patients With Relapsed or Progressive Cancer
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Thalidomide|DRUG: Celecoxib|DRUG: Etoposide|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Inhaled Iloprost in Pediatric Pulmonary Hypertension (PH) After Surgery
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: iloprost nebuliser solusion|DRUG: distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of a Ficus Carica in Subjects With Functional Constipation
Status: COMPLETED
Conditions: Functional Constipation
Interventions: DIETARY_SUPPLEMENT: Ficus Carica (300g/day)|DIETARY_SUPPLEMENT: Placebo (300g/day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Hyperbaric Oxygen Therapy (HBOT) on Acute Thermal Burns
Status: UNKNOWN
Conditions: Acute Thermal Burns
Interventions: PROCEDURE: Hyperbaric Oxygen Therapy|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT