pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Dalteparin Low Molecular Weight Heparin for Primary Prophylaxis of Venous Thromboembolism in Brain Tumour Patients
Status: COMPLETED
Conditions: Venous Thromboembolism|Brain Tumors
Interventions: DRUG: dalteparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The Influence of 5-HTTLPR and BDNF Polymorphisms on Anxiety and Mood After Acute Exercise
Status: COMPLETED
Conditions: Polymorphisms|Exercise|Mood
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Quiet rest
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU
Status: RECRUITING
Conditions: Pulmonary Edema|Pneumonia|Atelectasis|Pleural Effusion|Acute Rejection of Lung Transplant (Disorder)|Airway Obstruction|Rib Fractures|Acute Copd Exacerbation|Asthma COPD|Pulmonary Embolism|Hemothorax|Pneumothorax|Mesothelioma|Diaphragmatic Paralysis
Interventions: DIAGNOSTIC_TEST: Portable Dynamic Digital Radiography (DDR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression of Peripheral Arterial Disease (The ELIMIT Study)
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DRUG: Ezetimibe|DRUG: Niaspan|DRUG: Statin therapy|BEHAVIORAL: Standard care|DRUG: Aspirin|DRUG: Clopidogrel|DRUG: Placebo Niaspan|DRUG: Placebo Ezetimibe|PROCEDURE: Percutaneous transluminal angioplasty (PTA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Oxymizer Pendant Cannula Versus Conventional Nasal Cannula During Endurance Shuttle Walk Tests in Hypoxemic Patients With Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis|Hypoxemia
Interventions: DEVICE: Oxymizer® pendant nasal cannula|DEVICE: conventional nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peanut Allergy Oral Immunotherapy Study of AR101 for Desensitization in Children and Adults (PALISADE)
Status: COMPLETED
Conditions: Peanut Allergy
Interventions: BIOLOGICAL: AR101 powder provided in capsules & sachets|BIOLOGICAL: Placebo powder provided in capsules & sachets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Skin Tolerance and Efficacy of a Cosmetic Product After 4 Weeks of Use on Subjects With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Diathesis|Eczema-Prone Skin
Interventions: OTHER: Lotion BNO 3732|OTHER: Body Lotion Benchmark product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effect of Caffeine on Heart Function
Status: COMPLETED
Conditions: Fatigue|Tachycardia
Interventions: DIETARY_SUPPLEMENT: Monster Energy Drink|DIETARY_SUPPLEMENT: Monster energy drink|DIETARY_SUPPLEMENT: Monster Energy Drink|DIETARY_SUPPLEMENT: Coffee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immune Benefits From Mushroom Consumption
Status: COMPLETED
Conditions: Healthy Humans
Interventions: DIETARY_SUPPLEMENT: 3 ounces of mushrooms|DIETARY_SUPPLEMENT: 6 ounces of mushrooms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Omarigliptin (MK-3102) in Participants With Impaired Renal Function (MK-3102-009)
Status: COMPLETED
Conditions: Chronic Renal Insufficiency|Type 2 Diabetes Mellitus
Interventions: DRUG: Omarigliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dermacyd Femina Delicata (Lactic Acid)- Photo Dermatological Evaluation of the Irritation and Sensitivity Potential
Status: COMPLETED
Conditions: Hygiene
Interventions: DRUG: Lactic acid (Dermacyd Femina Delicata)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oral vs Rectal Admin of Naproxen for Post-Vag Perineal Pain Control
Status: COMPLETED
Conditions: Post-Vaginal Delivery Perineal Pain
Interventions: DRUG: Naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Restoration of Walking in Multiple Sclerosis Using Treadmill Training.
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DEVICE: Body-weight supported treadmill|DEVICE: Lokomat|DEVICE: Body-weight supported treadmill|DEVICE: Lokomat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Hemostatic Methods in Distal Radial Artery Approach for Cardiac Catheterization
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Intervention|Transradial Approach
Interventions: DEVICE: Hemostatic device for distal radial approach.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of SARS-COV-2 Viral Load of Covid-19 Patients After Rinsing With Oral Antimicrobial Mouthwashes
Status: COMPLETED
Conditions: Covid19
Interventions: OTHER: CPC+ZN|OTHER: CPC|OTHER: Negative Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open-label, Normal Healthy Volunteer Clinical Trial of a Novel Ondansetron Formulation
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ond-PR1|DRUG: Ond-PR1 + MPh-IR|DRUG: Ond-PR2|DRUG: Ond-PR2 +_ MPh-IR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Immunonutrition in Patients Undergoing Pancreaticoduodenectomy
Status: COMPLETED
Conditions: Pancreaticoduodenectomy
Interventions: DIETARY_SUPPLEMENT: Oral IMPACT|DIETARY_SUPPLEMENT: Oral IMPACT|DIETARY_SUPPLEMENT: Parenteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase II Randomized Bilateral Comparison of Topical Targretin Gel 1% in Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: Targretin Gel 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Glucosamine on Joint Fluid in Osteoarthritis Patients
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: Glucosamine sulphate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Welcoming by Design Pilot: Reducing Structural Stigma by Changing Clinic Systems and Architectural Design
Status: NOT_YET_RECRUITING
Conditions: Hiv
Interventions: OTHER: Clinics remodeling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Examine the Value of Broad Agnostic Next Generation Sequencing (NGS) Panel Testing Versus Reimbursed Organ-directed NGS: a Belgian Precision Study of the BSMO in Collaboration With the Cancer Center
Status: UNKNOWN
Conditions: Metastatic Cancer|Local Tumor Invasion
Interventions: DIAGNOSTIC_TEST: NGS testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Gravity Stent-Retriever System For Reperfusion Of Large Vessel Occlusion Stroke Trial
Status: RECRUITING
Conditions: Ischemic Stroke|Stroke|Cerebrovascular Disorders|Brain Diseases|Central Nervous System Diseases|Nervous System Diseases|Vascular Diseases|Cardiovascular Diseases
Interventions: DEVICE: Supernova revascularization device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib Combined With Radiotherapy in Patients With Non-resectable Locally Advanced Non-small Cell Lung Cancer (LA-NSCLC)
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Erlotinib|RADIATION: Thoracic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Healing Touch on Sleep
Status: COMPLETED
Conditions: Elective Reconstructive Surgery Population
Interventions: BEHAVIORAL: Healing Touch|BEHAVIORAL: Healing Touch, Sham|BEHAVIORAL: Control, Presence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Panobinostat + Bortezomib for Relapsed and/or Refractory Mantle Cell Lymphoma (MCL)
Status: COMPLETED
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Panobinostat|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glofitamab Plus Ibrutinib With Obinutuzumab for the Treatment of Patients With Mantle Cell Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Mantle Cell Lymphoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|PROCEDURE: FDG-Positron Emission Tomography|BIOLOGICAL: Glofitamab|DRUG: Ibrutinib|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thalidomide for the Symptomatic Large Granular Lymphocytic Leukemia
Status: RECRUITING
Conditions: T-LGL Leukemia|NK-LGL Leukemia
Interventions: DRUG: Thalidomide and methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Young Patients With Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: GENETIC: DNA analysis|GENETIC: DNA methylation analysis|GENETIC: RNA analysis|GENETIC: comparative genomic hybridization|GENETIC: mutation analysis|GENETIC: polymorphism analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Determine Long Term Efficacy and Safety of Asenapine in Schizophrenic Patient Population (A7501012)(COMPLETED)(P05770)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Asenapine - Open Label|DRUG: Placebo - Double Blind|DRUG: Asenapine - Double Blind
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Family Centered Developmental Intervention on Severely Acutely Malnourished Children
Status: COMPLETED
Conditions: Severly Acutely Malnourished Children
Interventions: BEHAVIORAL: Play-based family centered stimulation|OTHER: no intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Sentinel Lymph Node Navigation Surgery Using Near-infrared Imaging in Early Esophageal Cancer
Status: UNKNOWN
Conditions: Detection Rate of SLN ; Accuracy Rate of Lymph Node Metastasis
Interventions: DRUG: Indocyanine Green for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pretreatment With Dienogest in Women With Endometriosis Undergoing in Vitro-fertilization After a Previous Failed Cycle
Status: COMPLETED
Conditions: Endometriosis|Endometriosis Ovary|IVF
Interventions: DRUG: Dienogest 2 MG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of 3 Doses of Dextofisopam in Females With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Dextofisopam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment With MK0966 for the Prevention of Prostate Cancer (0966-201)
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: rofecoxib|DRUG: Comparator: placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Celecoxib|DRUG: Creatine|DRUG: Minocycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-acting Low Dose Ropeginterferon for Chronic Myeloid Leukemia Treated With Bosutinib From Diagnosis
Status: RECRUITING
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Bosutinib|DRUG: Ropeginterferon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Five-Treatment-Period Study to Evaluate the Single-Dose Pharmacokinetics and Pharmacodynamics of Avatrombopag in Healthy Japanese and White Subjects
Status: COMPLETED
Conditions: Thrombocytopenia
Interventions: DRUG: avatrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone (R-CHOP) or R-CHOP in Adult Participants With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)
Status: RECRUITING
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Epcoritamab|DRUG: Cyclophosphamide|DRUG: Rituximab|DRUG: Vincristine|DRUG: Doxorubicin|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Comparative Study of Fluconazole Versus Clotrimazole Troches in the Prevention of Serious Fungal Infection in Patients With AIDS or Advanced AIDS-Related Complex. (A Nested Study of ACTG 081)
Status: COMPLETED
Conditions: Candidiasis|Mycoses|HIV Infections
Interventions: DRUG: Clotrimazole|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Using Telehealth to Deliver Mental Health Services in Primary Care Settings for Children in Underserved Areas
Status: COMPLETED
Conditions: Developmental, Behavioral and Mental Health|Adhd|Depression|Anxiety|Developmental Delay|Autism|Behavioral Problems
Interventions: BEHAVIORAL: Telehealth Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Vitamin D Status in Children With Acute Burns
Status: COMPLETED
Conditions: Burns|Bone Demineralization
Interventions: DIETARY_SUPPLEMENT: Vitamin D2|DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diaphragmatic Breathing Exercises for Post-COVID-19 Diaphragmatic Dysfunction (DD)
Status: RECRUITING
Conditions: Post-Acute Sequelae of COVID-19
Interventions: OTHER: Usual care of traditional treatment|OTHER: Specific DB program/Diaphragmatic manipulation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Food Effect And Relative Bioavailability Study Of Oxycodone in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Oxycodone|DRUG: Oxycodone|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Radiotherapy & Total Neoadjuvant Therapy for Recurrent Rectal Cancer in Previously Irradiated Patients, an Italian Association for Radiotherapy and Clinical Oncology (AIRO)-GI Platform: a Multi-centre Prospective Observational Study
Status: RECRUITING
Conditions: Rectal Neoplasm
Interventions: RADIATION: Reirradiation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Targeting Inflammation With Losartan to Improve Response to Modulator Therapy in Cystic Fibrosis.
Status: RECRUITING
Conditions: Cystic Fibrosis
Interventions: DRUG: Losartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Goal-Directed Nutrition in ICU Patients - EAT-ICU Trial
Status: COMPLETED
Conditions: Critical Illness|Intensive Care (ICU) Myopathy|Muscle Wasting|Loss of Physical Function|Mechanical Ventilation
Interventions: OTHER: Early Goal-Directed Nutrition|OTHER: ASPEN-guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effect of Low-dose Esketamine Combined With Target-controlled Infusion of Propofol for Painless Gastrointestinal Endoscopy
Status: UNKNOWN
Conditions: Pain|Anesthesia
Interventions: DRUG: Propofol|DRUG: Esketamine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Healthy Meals: A Restaurant-based Study to Promote Healthy and Allergy Adapted Diet
Status: COMPLETED
Conditions: Intervention|Food Allergy|Food Preferences|Food Intolerance|Diet Habit|Diet Modification
Interventions: BEHAVIORAL: Multicomponent intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Family Intervention Following Traumatic Injury
Status: COMPLETED
Conditions: Acquired Brain Injury|Spinal Cord Injuries
Interventions: BEHAVIORAL: Group session psycho-education|BEHAVIORAL: FITS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SOAR: Study Observing Antiarrhythmic Remodelling Using LGE-MRI
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: dronedarone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Understanding Oxytocin's Neural and Behavioral Effects in Adolescents Diagnosed With Autism
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Oxytocin
Interventions: DRUG: Oxytocin: Including placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Current and Past SARS-CoV-2 Infection and COVID-19 in Healthcare
Status: COMPLETED
Conditions: SARS-CoV 2
Interventions: DIAGNOSTIC_TEST: Throat swab sample for measuring current infection with SARS-CoV-2|DIAGNOSTIC_TEST: Blood sample for serology to measure past infection with SARS-CoV-2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Romosozumab (EVENITY®) in Postmenopausal Women in India With Osteoporosis at a High Risk of Fracture.
Status: RECRUITING
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Romosozumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: International, Multicenter, Open-Label and Randomized Withdrawal Study of Oral Lixivaptan in Heart Failure Patients With Chronic Hyponatremia
Status: WITHDRAWN
Conditions: Hypervolemic Hyponatremia
Interventions: DRUG: Lixivaptan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing the Management of Staphylococcus Aureus Bacteremia (OPTIMUS-SAB)
Status: RECRUITING
Conditions: Staph Aureus Bacteremia
Interventions: OTHER: OPTIMUS-SAB clinical care pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TATE and Pembrolizumab (MK3475) in mCRC and NSCLC
Status: RECRUITING
Conditions: Colorectal Cancer; Lung Cancer
Interventions: DRUG: TATE and pembrolizumab|DRUG: TAS-102 pill|DRUG: Regorafenib Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percussion Palm Cup: Safety and Usability in Infants and Children With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis in Children
Interventions: DEVICE: Percussion Palm Cup: Safety and Usability of Newly Designed Products in Infants and Children with Cystic Fibrosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: HC-1119 Adjuvant Treatment for Hospitalized COVID-19 Patients
Status: UNKNOWN
Conditions: COVID-19 Respiratory Infection
Interventions: DRUG: HC-1119|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NGX-4010 for the Treatment of Postherpetic Neuralgia
Status: COMPLETED
Conditions: Herpes Zoster|Neuralgia|Pain|Peripheral Nervous System Diseases|Shingles
Interventions: DRUG: Capsaicin Dermal Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: FlexWave Trial: Efficacy of Extracorporeal Shock Wave Therapy in Post-Stroke Upper Limb Spasticity
Status: RECRUITING
Conditions: Stroke|Spasticity, Muscle
Interventions: DEVICE: focused extracorporeal shock wave therapy (ESWT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Function of Tamsulosin in Older Males Undergoing Surgery With Indwelling Catheter
Status: RECRUITING
Conditions: Postoperative Urinary Tract Infection
Interventions: DRUG: Tamsulosin|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Inhaled Prostaglandin E1 (IPGE1) for Hypoxemic Respiratory Failure (NHRF)
Status: TERMINATED
Conditions: Prematurity|Respiratory Insufficiency|Pulmonary Hypertension|Respiratory Distress Syndrome, Newborn
Interventions: DRUG: Aerosolized Normal Saline|DRUG: Inhaled PGE1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of Cannabis Based Medicine in Patients With Pain of Neurological Origin
Status: COMPLETED
Conditions: Pain|Multiple Sclerosis
Interventions: DRUG: GW-1000-02|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Discharge Information and Support for Patients Receiving Outpatient Care in the Emergency Department
Status: COMPLETED
Conditions: Multimorbidity
Interventions: BEHAVIORAL: DISPO ED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Discontinuation vs Continuation of Long-term Opioid Therapy in Suboptimal and Optimal Responders With Chronic Pain
Status: TERMINATED
Conditions: Opioid-Related Disorders|Opiate Addiction|Narcotic Abuse|Drug Abuse
Interventions: DRUG: Structured discontinuation of opioid therapy (morphine sulfate ER, oxycodone ER, oxymorphone ER)|DRUG: Continuation of opioid therapy (morphine sulfate ER, oxycodone ER, oxymorphone ER)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Arm Phase II Study to Evaluate Treatment With Gevokizumab in Patients With Stage II/III Colon Cancer Who Are ctDNA-positive After Curative Surgery and Adjuvant Chemotherapy
Status: WITHDRAWN
Conditions: Colon Cancer
Interventions: DRUG: Gevokizumab|DIAGNOSTIC_TEST: Signatera test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Dose Taken in Opioid Use Disordered Patients With an Electrochemical Sensor
Status: NOT_YET_RECRUITING
Conditions: Adherence, Medication|Opioid Use Disorder
Interventions: DEVICE: Remote Medication Monitor (RMM) - Prototype|DRUG: Daily Methadone Dose
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of Lactobacillus Administered Vaginally to Healthy Women
Status: COMPLETED
Conditions: Bacterial Vaginosis
Interventions: BIOLOGICAL: Low dose LACTIN-V applicator|BIOLOGICAL: Medium dose LACTIN-V applicator|BIOLOGICAL: High dose LACTIN-V applicator|OTHER: Low dose Placebo applicator|OTHER: Medium dose Placebo|OTHER: High dose Placebo applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Uric Acid, Klotho and Salt Sensitivity in Young Adults Born Preterm
Status: RECRUITING
Conditions: Salt; Excess|Blood Pressure Disorders
Interventions: DRUG: Allopurinol|OTHER: Dietary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intervention for Improving Asthma Care for Minority Children in Head Start
Status: COMPLETED
Conditions: Asthma|Lung Diseases
Interventions: BEHAVIORAL: Facilitated Asthma Communication Intervention (FACI)|BEHAVIORAL: Breathmobile intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Relative Bioavailability of Empagliflozin (BI 10773) (Final Formulation) Compared to Empagliflozin (BI 10773 XX) (Trial Formulation 2) in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 10773 XX (Trial Formulation 2)|DRUG: BI 10773 (Final Formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemokine Coreceptor 5 (CCR5) Antagonist GW873140 In R5-Tropic Treatment-Experienced HIV-Infected Subjects
Status: TERMINATED
Conditions: HIV Infection
Interventions: DRUG: GW873140
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lidocaine on Postoperative Pain and Long-term Survival in Elderly Patients Undergoing Colorectal Surgery
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: lidocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Preventive Effects of Penehyclidine Hydrochloride Inhalation on Postoperative Pulmonary Complications
Status: COMPLETED
Conditions: Postoperative Complications
Interventions: DRUG: Penehyclidine inhalation|DRUG: Placebo inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Adverse Effects Surgery|MRI|Ultrasound|Sexual Function Disturbances|Urinary Incontinence|Urinary Function Disorders|Prostate Biopsy|Ablation
Interventions: DEVICE: TRANBERG® Transperineal Fusion Laser--Induced Thermal Therapy of Prostate Cancer (TPF-LITT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiviral Pharmacology and Adherence in Drug Users
Status: COMPLETED
Conditions: HEPATITIS C|Virus, Human Immunodeficiency
Interventions: BEHAVIORAL: Directly Observed Therapy|BEHAVIORAL: Wirelessly Observed Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study To Evaluate The Safety, Tolerability And Plasma Drug Levels Of PF-04447943 When Administered With Donepezil To Healthy Volunteer Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-04447943 25 mg|DRUG: Placebo PF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Efficacy of FX06 in the Prevention of Myocardial Reperfusion Injury
Status: COMPLETED
Conditions: Myocardial Ischemia|Coronary Disease|Myocardial Infarction
Interventions: DRUG: FX06|PROCEDURE: Percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Effects of Avanafil on Semen Parameters
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: avanafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nilotinib and LDE225 in the Treatment of Chronic or Accelerated Phase Myeloid Leukemia in Patients Who Developed Resistance to Prior Therapy
Status: COMPLETED
Conditions: Philadelphia Chromosome Positive Chronic Myelogenous Leukemia
Interventions: DRUG: Nilotinib + LDE225
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: [18F]Fluciclovine and [18F]FLT PET/CT Assessment of Primary High-Grade Brain Tumors
Status: RECRUITING
Conditions: Brain Tumor
Interventions: DRUG: Multi-tracer PET exams of [18F]FLT and [18F]Fluciclovine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of ThermoDox™ in Combination With Radiofrequency Ablation (RFA) in Primary and Metastatic Tumors of the Liver
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Liver Neoplasms
Interventions: DRUG: ThermoDox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Autologous Cord Blood Mononuclear Cells for Digestive System in Preterm Neonates
Status: UNKNOWN
Conditions: Neonatal Necrotizing Enterocolitis|Growth and Development|Preterm Infants|Nutrition
Interventions: OTHER: Autologous Umbilical Cord Blood Mononuclear Cells Therapy|DRUG: 0.9% Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Afatinib in Previously Treated ESCC With EGFR Overexpression or EGFR Amplification (ESCC-A01)
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Care Implementation Study to Scale up EIBI and Reduce Alcohol Related Negative Outcomes
Status: UNKNOWN
Conditions: Harmful; Use, Alcohol|Hazardous; Use, Alcohol
Interventions: BEHAVIORAL: Training and support|BEHAVIORAL: Community actions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Study of SP-02L in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)
Status: COMPLETED
Conditions: Peripheral T-Cell Lymphoma
Interventions: DRUG: SP-02L (darinaparsin for injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Plantar Foot Pressure in a Novel Diabetic Offloading Device
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: PulseFlow DF boot|DEVICE: Usual standard of care|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: To Demonstrate the Relative Bioavailability of Fluoxetine Hydrochloride Capsules, 40 mg
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Fluoxetine Hydrochloride Capsules, 40 mg (Geneva Pharmaceutical, Inc)|DRUG: Fluoxetine Hydrochloride Capsules, 40 mg (Prozac) (Eli Lilly)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating KardioPAC Mobile App to Improve Physical Fitness Among Cardiac Rehabilitation Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiac Rehabilitation|Exercise|Quality of Life
Interventions: BEHAVIORAL: KardioPAC Mobile Application|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Exercise, Arterial Cross-Talk Modulation and Inflammation in an Ageing Population
Status: COMPLETED
Conditions: Cardiovascular Disease|Obesity|Atherosclerosis|Heart; Disease, Activity
Interventions: OTHER: Training or control condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: From the Heart: Comparing the Effects of Spiritual and Secular Meditation on Psychophysiology, Cognition, Mental Health, and Social Functioning in Healthy Adults
Status: RECRUITING
Conditions: Prosocial Behavior|Forgiveness|Empathy|Pain|Attention|Depression|Stress|Anxiety|Mental Well-being
Interventions: BEHAVIORAL: Arm 1 - Heart-Centred Spiritual Meditation: Christian contemplation|BEHAVIORAL: Arm 1 - Heart-Centred Spiritual Meditation: Islamic contemplation|BEHAVIORAL: Arm 2 - Action Control: Mindfulness Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acupuncture Study on Rheumatoid Arthritis, Monitoring Microbiome and Blood
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: methotrexate|DRUG: non-steroidal anti-inflammatory drug (NSAID)|DRUG: leflunomide|DRUG: methotrexate|DRUG: non-steroidal anti-inflammatory drug (NSAID)|DRUG: leflunomide|PROCEDURE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: VAY736 in Combination With Ibrutinib in Patients With CLL on Ibrutinib
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia (CLL)
Interventions: DRUG: VAY736|DRUG: ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study to Improve Colorectal Cancer Screening Among Racially Diverse Zip Codes in a Persistent Poverty County Using Navigation and Machine Learning Predictive Algorithms
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: OTHER: Machine Learning Algorithm with Existing Penn Medicine CRC Patient Navigation Program
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Otago Exercise Program And Gaze Stability Exercise In Older Adults
Status: COMPLETED
Conditions: Balance
Interventions: OTHER: Otago exercises and core strengthening|OTHER: Gaze stability exercises and core strengthening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of the Dreem 3S Ambulatory Sleep Monitoring Device for the Evaluation of Narcolepsy
Status: RECRUITING
Conditions: Narcolepsy Type 1|Hypersomnia|Sleep Disorder
Interventions: DEVICE: Dreem 3S recording
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Isoamyl 2-Cyanoacrylate in the Urethro-cutaneous Fistula Repair
Status: COMPLETED
Conditions: Hypospadias
Interventions: DRUG: Cyanoacrylate, Isobutyl|PROCEDURE: Classic surgical repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sexual Orientation and Gender Identity (SOGI) Data Collection Program Implementation and Evaluation
Status: RECRUITING
Conditions: Cancer Surveillance
Interventions: OTHER: Patient SOGI Self-Report|OTHER: SOGI Resource for Clinical Care Education (SORCE)|OTHER: Cancer Center Care Environment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Build-up of Action Representation in Autism Spectrum Disorders
Status: COMPLETED
Conditions: Healthy|Autism Spectrum Disorder
Interventions: OTHER: Behavioral assessments|OTHER: Magnetoencephalography (MEG)|OTHER: Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Designing a Bayesian Model of the Plasma Clearance of Calcium Edetate de Sodium for the Calculation of GFR and Validity Compared to the Renal Clearance of Inulin
Status: COMPLETED
Conditions: Kidney Disease
Interventions: DRUG: Dosage of Calcium edetate de sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Defining the Role of Palliative carE for Patients With Hematologic Malignancies Undergoing Adoptive CEllular Therapy
Status: RECRUITING
Conditions: Hematologic Malignancy|Blood Cancer|Lymphoma|Leukemia|Multiple Myeloma
Interventions: BEHAVIORAL: Palliative Care|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Evaluate SSD8432/ Ritonavir in Adults With COVID-19
Status: COMPLETED
Conditions: COVID-19 Patients
Interventions: DRUG: SSD8432 dose 1/Ritonavir|DRUG: SSD8432 dose 2/Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option
Status: RECRUITING
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Macitentan|DRUG: Selexipag|DRUG: Macitentan/Tadalafil FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Link Between Obesity And Vitamin D in Bariatric Patients With Omega-loop Bypass Surgery
Status: COMPLETED
Conditions: Bariatric Surgery Candidate
Interventions: DRUG: Cholecalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: KORE-Innovation: a Prospective, Multi-site Clinical Trial to Implement and Analyse the Effects of an Innovative Perioperative Care Pathway to Reduce Complications for Patients With Ovarian Cancer
Status: RECRUITING
Conditions: Ovary Cancer|Fallopian Tube Cancer|Peritoneum Cancer|Frailty
Interventions: OTHER: Implementation of an innovative multi-modal peri-operative care pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparative Study of the Cornea/Anterior Segment OCT CASIA2 and the RTVue XR OCT Avanti With AngioVue Software
Status: COMPLETED
Conditions: Glaucoma|Cataract
Interventions: DEVICE: Cornea/Anterior Segment OCT CASIA2|DEVICE: Optovue RTVue XR Avanti
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Prospective, Randomized Trial to Compare saroGLitazar With pioglitAZone in Nonalcoholic Fatty livEr Disease
Status: UNKNOWN
Conditions: Fatty Liver
Interventions: DRUG: Saroglitazar|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Graded Exposure Therapy for Fear Avoidance Behaviour After Concussion
Status: RECRUITING
Conditions: Mild Traumatic Brain Injury
Interventions: BEHAVIORAL: Graded Exposure Therapy|BEHAVIORAL: Prescribed aerobic exercise|OTHER: Enhanced usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin and Cyclophosphamide (AC) Followed by Weekly Docetaxel as Neoadjuvant Treatment of Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cilostazol in Promoting Hematoma Clearance After Intracerebral Hemorrhage
Status: NOT_YET_RECRUITING
Conditions: ICH - Intracerebral Hemorrhage
Interventions: DRUG: Cilostazol 50 MG Oral Tablet|PROCEDURE: Conventional internal medicine treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Safety, and Efficacy Trial of WR 279,396 (Paromomycin + Gentamicin Topical Cream) and Paromomycin Topical Cream for the Treatment of Cutaneous Leishmaniasis in Panama
Status: COMPLETED
Conditions: Leishmaniasis, Cutaneous
Interventions: DRUG: WR 279,396 (15% paromomycin + 0.5% gentamicin topical cream)|DRUG: Paromomycin Alone Cream (15% paromomycin topical cream)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Modulation of Metabolic Rate by Inorganic Nitrate
Status: COMPLETED
Conditions: Resting Metabolic Rate
Interventions: OTHER: Glucose Uptake|OTHER: Resting metabolic rate|OTHER: Nitrite infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Brain Function and EEG
Status: COMPLETED
Conditions: Healthy|Mood
Interventions: DRUG: Methamphetamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Ketogenic Diet in Divers Breathing Enriched Air Nitrox
Status: COMPLETED
Conditions: Overweight and Obesity|Exertion; Excess|Oxygen Toxicity
Interventions: DIETARY_SUPPLEMENT: Ketogenic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Palmitoylethanolamide on Reducing Opioid Consumption for Below Knee Fracture Fixation
Status: WITHDRAWN
Conditions: Tibial Fractures|Fibula Fracture|Knee Fracture
Interventions: DRUG: Palmitoylethanolamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Demonstrate Efficacy and Safety of Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: CT-P6|DRUG: Herceptin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study Between Two Formulations of the Ciprofloxacin Hydrochloride + Hydrocortisone Otic Suspension
Status: COMPLETED
Conditions: Otitis Externa
Interventions: DRUG: Cipro HC|DRUG: Ciprofloxacin HCl and Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Irritation Study of Two Experimental Mouthrinses
Status: COMPLETED
Conditions: Oral Manifestations
Interventions: DEVICE: Potassium Oxalate without Fluoride|DEVICE: Potassium Oxalate with Fluoride|DEVICE: Active Comparator PO-116-A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE