pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Hernia After Colorectal Cancer Surgery
Status: UNKNOWN
Conditions: Incisional Hernia|Wound Dehiscence|Wound Complication|Quality of Life
Interventions: PROCEDURE: 4:1 closure group|PROCEDURE: RTL plus 4:1 closure group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Safety and Utility of Skin Testing With XOLAIR® (Omalizumab) and Placebo Omalizumab (Formulation Excipients)
Status: COMPLETED
Conditions: Healthy|Asthma
Interventions: DRUG: Cohort I|DRUG: Cohort 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Leucine and Isoleucine on Glucose Metabolism
Status: COMPLETED
Conditions: Hyperglycemia
Interventions: DIETARY_SUPPLEMENT: Leucine Supplement|DIETARY_SUPPLEMENT: Isoleucine Supplement|DIETARY_SUPPLEMENT: Leucine Supplement combined with Isoleucine Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multi-center, Open-labelled, Randomized, Controlled, Extended Phase Ⅲ Clinical Trial of sIPV Vaccine
Status: RECRUITING
Conditions: Poliomyelitis|Polio
Interventions: BIOLOGICAL: Sabin Strain Inactivated Poliovirus Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Do Endotypes Predict Response and Sequelae in OSA Patients
Status: RECRUITING
Conditions: Obstructive Sleep Apnea|Sleep Apnea|Sleep Apnea, Obstructive|Sleep|Sleep Disorder
Interventions: DRUG: Eszopiclone|OTHER: Supplemental Oxygen|DEVICE: Continuous Positive Airway Pressure (CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intraoperative Dexmedetomidine on Postoperative Delirium in Elderly Patients Undergoing Major Abdominal Surgery
Status: RECRUITING
Conditions: Delirium in Old Age
Interventions: OTHER: saline|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Questionnaire Study for Gynecological Cancer Survivors
Status: UNKNOWN
Conditions: Endometrial Neoplasms|Ovarian Neoplasms|Uterine Cervical Neoplasms|Vulvar Neoplasms|Vaginal Neoplasms|Genital Neoplasms, Female
Interventions: BEHAVIORAL: Psychosocial
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hypotension Prediction Index in Major Gastrointestinal Surgery
Status: COMPLETED
Conditions: the Effect of Hypotension Prediction Index Application
Interventions: DEVICE: hypotension prediction index guided|DEVICE: without hypotesion prediction index guided
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Ruxolitinib in Combination With Nilotinib in Chronic Myeloid Leukemia (CML) Patients
Status: COMPLETED
Conditions: Chronic Phase Chronic Myeloid Leukemia
Interventions: DRUG: Nilotinib|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioavailability of Sandoz Inc. and Tyco Healthcare (Tofranil) 50 mg Imipramine Hydrochloride Tablets In Healthy Adults Volunteers Under Fasting Conditions
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Imipramine Hydrochloride 50 mg Tablets (Sandoz Inc.)|DRUG: Tofranil Imipramine Hydrochloride 50 mg Tablets (Tyco Healthcare)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Nivolumab and BMS-986016 (Relatlimab) as Potentially Targeting Treatment in Cancers That Are LAG-3+ and Have Mismatch Repair Deficiency (MATCH - Subprotocol Z1M)
Status: WITHDRAWN
Conditions: Advanced Lymphoma|Advanced Malignant Solid Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Multiple Myeloma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Nivolumab|BIOLOGICAL: Relatlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study to Evaluate SIM0270 Alone or in Combination in ER+, HER2- Locally Advanced or Metastatic Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: SIM0270|DRUG: Palbociclib|DRUG: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Immunonutrition, Phagocytic and Bactericidal Activity of Blood Platelets in Gastric Cancer Patients
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DIETARY_SUPPLEMENT: Early postoperative enteral nutrition, based on standard elementary diet (Peptisorb)|DRUG: glutamine|DIETARY_SUPPLEMENT: oral diet enriched with arginine (Cubitan)|DRUG: Perioperative parenteral immunonutrition (Dipeptiven, Omegaven)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trials to Evaluate the Efficacy and Safety of Tenofovir With and Without DWPUR001 in Patients With HBV
Status: UNKNOWN
Conditions: Hepatitis; Virus, Chronic, Type B
Interventions: DRUG: DWPUR001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Atezolizumab in Combination With an Immunotherapy Agent Investigated With or Without Anti-Cd20 Therapy in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma
Status: WITHDRAWN
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: Atezolizumab|DRUG: Emactuzumab|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining Adolescent Assessment, Feedback, Incentive, and Exchange (AFIX) in North Carolina
Status: COMPLETED
Conditions: Adolescent Health Services|Immunization
Interventions: OTHER: Assessment , Feedback, Incentives, and eXchange Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Development of Cognitive Assessment Tools in Parkinson Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: [123I] IBVM and SPECT imaging|DRUG: Subjects will undergo the 123-I IBVM imaging visit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safety and Immunogenicity of Rotavirus Vaccine (RotaTeq(R)) in Infants With Short Bowel Syndrome
Status: COMPLETED
Conditions: Short Bowel Syndrome
Interventions: BIOLOGICAL: Oral, live, pentavalent rotavirus vaccine; RotaTeq(R)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Enhancing Emotion Regulation During Driving in OEF/OIF Veterans
Status: COMPLETED
Conditions: Driving Distress Secondary to Trauma During Deployment
Interventions: BEHAVIORAL: Cognitive reappraisal and breathing retraining|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Targeted Plasticity Therapy for PTSD
Status: NOT_YET_RECRUITING
Conditions: PTSD, Post Traumatic Stress Disorder
Interventions: DEVICE: Active VNS stimulation|DEVICE: Sham VNS stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing a Prophylactic With a Therapeutic Platelet Transfusion Strategy in Two Groups
Status: COMPLETED
Conditions: Myeloid Leukemia
Interventions: BIOLOGICAL: Prophylactic platelet transfusion|BIOLOGICAL: Therapeutic platelet transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 12-hour Versus 24-hour Postpartum Magnesium Sulphate for Preeclamptic Patients
Status: COMPLETED
Conditions: Maternal Care Patterns
Interventions: DRUG: Magnesium sulfate for 12 hour|DRUG: Magnesium sulfate for 24 hour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized Pilot Study to Evaluate the Effects of a Short Course of Metformin Versus No Therapy in the Period Prior to Hysterectomy for Grade 1-2 Adenocarcinoma of the Endometrium in Obese Non-Diabetic Women
Status: COMPLETED
Conditions: Adenocarcinoma of the Endometrium
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: JAK 1/2 Inhibitor, Baricitinib, in the Treatment of Adult IIM
Status: COMPLETED
Conditions: Idiopathic Inflammatory Myopathies
Interventions: DRUG: Baricitinib|DRUG: Baricitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Extension Study of Teduglutide in Japanese Participants With Short Bowel Syndrome Who Completed 24 Weeks of Treatment in SHP633-306 or TED-C14-004
Status: COMPLETED
Conditions: Short Bowel Syndrome
Interventions: DRUG: Teduglutide|DEVICE: Syringe|DEVICE: Needle|DEVICE: Vial Adapter for Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Vamorolone in Boys With Duchenne Muscular Dystrophy (DMD)
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Vamorolone 0.25 mg/kg/day|DRUG: Vamorolone 0.75 mg/kg/day|DRUG: Vamorolone 2.0 mg/kg/day|DRUG: Vamorolone 6.0 mg/kg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial Evaluating Irinotecan Plus 5FU/LV in Patients With Relapsed/Refractory Upper GI Tumours
Status: COMPLETED
Conditions: Upper Gastrointestinal Tumours
Interventions: DRUG: Irinotecan, 5-Fluorouracil, Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ultrasound Guided Peripheral Catheterization Increases First-attempt Success Rate
Status: COMPLETED
Conditions: Peripheral Venous Catheterization|Ultrasonography
Interventions: DEVICE: Ultrasound-guided peripheral venipuncture|DEVICE: Conventional peripheral venipuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Thiamine on Serum Glucagon And Reactive Oxygen Species (ROS)
Status: COMPLETED
Conditions: Sepsis|Thiamine Deficiency
Interventions: DRUG: Vitamin B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neurodynamic Intervention for Lumbar Radiculopathy
Status: COMPLETED
Conditions: Lumbar Radiculopathy
Interventions: OTHER: Motor Control Exercises|OTHER: Motor Control Exercise Plus Neurodynamic Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Real-life Study to Understand the Use and Effects of Palbociclib in US Patients With Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Malignant Neoplasm of Breast
Interventions: DRUG: Palbociclib|DRUG: Aromatase inhibitor|DRUG: Ribociclib|DRUG: Abemaciclib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dropless Pars Plana Vitrectomy Study
Status: RECRUITING
Conditions: Rhegmatogenous Retinal Detachment
Interventions: PROCEDURE: Pars plana vitrectomy|DRUG: Triamcinolone Acetonide 40mg/mL|DRUG: Moxifloxacin 0.5% or Polymyxin/Trimethoprim if patient is allergic to moxifloxacin|DRUG: Prednisolone 1%|DRUG: Atropine 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunologic Impact of Dupilumab in Patients Suffering From Asthma and Chronic Rhinosinusitis With Polyps
Status: NOT_YET_RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps|Asthma
Interventions: DRUG: Dupilumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Three Month Course of Anti-HIV Medications for People Recently Infected With HIV
Status: WITHDRAWN
Conditions: HIV Infections
Interventions: DRUG: Emtricitabine|DRUG: Nevirapine|DRUG: Tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of ALD518 for Reducing Oral Mucositis in Head and Neck Cancer Subjects
Status: TERMINATED
Conditions: Oral Mucositis
Interventions: BIOLOGICAL: ALD518|DRUG: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gamma Secretase Inhibitor PF-03084014 in Treating Patients With AIDS-Associated Kaposi Sarcoma
Status: WITHDRAWN
Conditions: AIDS-related Kaposi Sarcoma|HIV Infection|Recurrent Kaposi Sarcoma
Interventions: DRUG: gamma secretase inhibitor PF-03084014|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pedometer Assisted Physical Activity in Individuals With COPD. A Multicenter Randomized Controlled Trial.
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DEVICE: pedometer home based rehabilitation|OTHER: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closing -TB GAPs - for People Living With HIV: TB Guidance for Adaptable Patient-Centered Service
Status: RECRUITING
Conditions: Tuberculosis|HIV Coinfection|Tuberculosis Infection
Interventions: OTHER: patient-centered TB preventive therapy|OTHER: TB preventive therapy adherence support
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of the Use of Computer Game- "My Diabetic Friend" in Children With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: Interactive computer game|BEHAVIORAL: Convertible PC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Development of Ultra-Low Dose CT Based Screening for Aortic Aneurysms
Status: COMPLETED
Conditions: Aortic Aneurysm, Thoracic|Aortic Aneurysm, Abdominal
Interventions: OTHER: Ultra Low-Dose CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Periodontal Regeneration Versus Tooth Extraction and Replacement Denture in Teeth With Periodontal Hopeless Prognosis
Status: COMPLETED
Conditions: Periodontitis Complex
Interventions: DEVICE: Enamel matrix derivative, bone replacement graft, barrier membrane|PROCEDURE: Tooth extraction and replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors
Status: RECRUITING
Conditions: Healthy Volunteer|Prostate Cancer|Head and Neck Cancer|Esophageal Cancer|Genitourinary Cancer|Sarcoma|Breast Cancer|Colon Cancer|Gastrointestinal Cancer|Solid Tumor Cancer|Lung Cancer|Skin Cancer|Melanoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An fMRI Study in Healthy Volunteers to Investigate the Effects of ABX-1431 on Experimental Hyperalgesia and Its Neural Correlates
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: ABX-1431|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Safety, Pharmacokinetics, and Anti-Tumor Activity of Oral HP518 in Patients With Metastatic Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: HP518 - Dose Escalation|DRUG: HP518 - Dose expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics for Liver Cirrhosis With Portal Hypertension
Status: COMPLETED
Conditions: Liver Cirrhosis|Portal Hypertension
Interventions: DIETARY_SUPPLEMENT: GK#10|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transcutaneous Electrical Acustimulation in the Treatment of Mild to Moderate Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DEVICE: transcutaneous electrical acustimulation at treatment sites|DEVICE: transcutaneous electrical acustimulation at sham sites
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Durvalumab and Epacadostat for Treatment of Unresectable, Recurrent, or Metastatic Epstein-Barr Virus Positive Nasopharyngeal Cancer
Status: WITHDRAWN
Conditions: Epstein-Barr Virus Positive|Metastatic Nasopharyngeal Carcinoma|Recurrent Nasopharyngeal Carcinoma|Stage III Nasopharyngeal Carcinoma|Stage IV Nasopharyngeal Carcinoma|Stage IVA Nasopharyngeal Carcinoma|Stage IVB Nasopharyngeal Carcinoma
Interventions: BIOLOGICAL: Durvalumab|DRUG: Epacadostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combining Erlotinib Plus Bevacizumab and Gemcitabine Plus Capecitabine to Treat Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine 1000 mg/m2 iv days 1, 8, 15 of a 28 day cycle|DRUG: Capecitabine orally days 1 -21|DRUG: Erlotinib 100 mg orally days 1-28|DRUG: Bevacizumab 5 mg/kg intravenously every 2 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Placebo-Controlled Study of Aerobic Exercise and Resistance Training Plus Megestrol Acetate for HIV-Wasting
Status: COMPLETED
Conditions: Acquired Immunodeficiency Syndrome|HIV Wasting Syndrome|HIV Infections
Interventions: DRUG: megestrol|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: An Open, Randomized, Two Way Crossover Study Comparing the Effect of 20mg Esomeprazole Administered Orally and Intravenously as a 15 Minute Infusion on Basal and Pentagastrin-Stimulated Acid Output in Subjects With Symptoms of Gastroesophageal Reflux Disease (GERD)
Status: COMPLETED
Conditions: GERD
Interventions: DRUG: Esomeprazole|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation Therapy Device for the Treatment of Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Neuromodulation Therapy Device (NMTD)|DEVICE: Neuromodulation Therapy Device (NMTD)|DEVICE: Neuromodulation Therapy Device (NMTD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of HD-tDCS and Cognitive Training to Improve Cognitive Function in MCI
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Memory Disorders|Memory Loss
Interventions: DEVICE: HD-tDCS combined with CT|DEVICE: sham HD-tDCS combined with CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Benefit of Laparoscopic Adhesiolysis in Patients With Chronische Abdominal Pain
Status: COMPLETED
Conditions: Chronic Pain|Adhesions
Interventions: PROCEDURE: Laparoscopic adhesiolysis|PROCEDURE: Diagnostic laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess Allisartan Isoproxil/Amlodipine in Patients With Essential Hypertension Uncontrolled With Amlodipine or Allisartan Isoproxil
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Allisartan Isoproxil/Amlodipine group 1|DRUG: Amlodipine group 1|DRUG: Allisartan Isoproxil/Amlodipine group 2|DRUG: Allisartan Isoproxil group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics of a Single Dose of Cenerimod
Status: RECRUITING
Conditions: Healthy|Hepatic Impairment
Interventions: DRUG: Cenerimod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sequential Regimen of Bendamustin-Debulking Followed by Obinutuzumab, Acalabrutinib and Venetoclax in Patients With Relapsed/Refractory CLL
Status: COMPLETED
Conditions: Chronic Lymphoid Leukemia
Interventions: DRUG: Bendamustine|BIOLOGICAL: Obinutuzumab|BIOLOGICAL: Acalabrutinib|BIOLOGICAL: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Solifenacin Succinate (VESIcare) for the Treatment of Overactive Bladder in Parkinson's Disease
Status: COMPLETED
Conditions: Overactive Bladder in Parkinson's Disease
Interventions: DRUG: solifenacin succinate (VESIcare)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study on the Combined Magnetic and Oxygen Treatment for Bell's Palsy
Status: COMPLETED
Conditions: Bell's Palsy
Interventions: DRUG: prednisone and valacyclovir treatments|DEVICE: Magnetic and Oxygen Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of a Universal Adhesive in Noncarious Cervical Lesions
Status: COMPLETED
Conditions: Cervical Lesions
Interventions: PROCEDURE: Self etch enamel etching|PROCEDURE: selective etch protocol|DEVICE: Adhese Universal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Biphasic Insulin Aspart 30 Combined With Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes Inadequately Controlled With Basal Insulin
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 30|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Abbott RealTime CT/NG to Detect Chlamydia Trachomatis [CT] & Neisseria Gonorrhoeae [NG] in Men Who Have Sex With Men [MSM]
Status: TERMINATED
Conditions: Chlamydia Infection|Gonococcal Infection|Sexually Transmitted Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Leflunomide for Musculoskeletal GVHD After Allogeneic Stem Cell Transplant
Status: UNKNOWN
Conditions: Musculoskeletal Disease Other|GVHD, Chronic
Interventions: DRUG: Leflunomide tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided ESP Block vs. Wound Infiltration in Lumbar Surgery: A Comparative Analysis (ESP:Erector Spinae Plane)
Status: COMPLETED
Conditions: Lumbar Spinal Stenosis|Lumbar Spine Instability|Lumbar Spine Degeneration
Interventions: PROCEDURE: Erector Spinae Plane Block(ESPB)|PROCEDURE: Wound infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Obesity and Nonalcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DRUG: Niacin|DRUG: fenofibrate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Two Different Preoperative Training Densities in Patients With Non-small-cell Lung Cancer Before Lung Resection Surgery
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: OTHER: Preoperative Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Twice-Daily Individual Targeted Exercise Program in Frail Hospitalised Older Medical In-patients (RCT)
Status: COMPLETED
Conditions: Frail Older Adults
Interventions: OTHER: Intervention exercise|OTHER: Sham Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-term, Phase 3 Study of TVP-1012 (1 mg) in Levodopa Treated Parkinson's Disease Participants
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: TVP-1012 1mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BE Smokefree: Behavioral Economics Incentives to Engage Adolescents in Smoking Cessation
Status: TERMINATED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Quitline Incentive|BEHAVIORAL: Tobacco Cessation Incentive|BEHAVIORAL: Way to Health (WTH) Platform|BEHAVIORAL: Quitline Delivered Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Pharmacodynamics Study of Gemcabene in Healthy Volunteers
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Gemcabene 50 mg|DRUG: Gemcabene 150 mg|DRUG: Gemcabene 450 mg|DRUG: Gemcabene 750/600 mg|DRUG: Gemcabene 900 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing the Impact of 2 Different Techniques in Management of Hydrosalpinx on Pregnancy Rates Following ICSI
Status: COMPLETED
Conditions: Hydrosalpinx
Interventions: PROCEDURE: Laparoscopic salpingectomy|PROCEDURE: Hystroscopic proximal tubal occlusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of Venous Outflow From the Lower Limbs in Patients With Pelvic Varicosities
Status: RECRUITING
Conditions: Pelvic Varices|Varicose Veins of Lower Limb|Pelvic Pain Syndrome|Pelvic Congestive Syndrome
Interventions: DIAGNOSTIC_TEST: Radionuclide venography|DIAGNOSTIC_TEST: single-photon emission computed tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Eucaloric High-Protein Fiber Diet in Healthy Adults: A Repeated Single-Arm Clinical Trial
Status: COMPLETED
Conditions: Dietary Exposure
Interventions: DIETARY_SUPPLEMENT: Isomalto Oligosaccharide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Hypnotherapy in Patients With Chest Pain & Unobstructed Coronaries
Status: WITHDRAWN
Conditions: Chest Pain|Unobstructed Coronary Arteries
Interventions: BEHAVIORAL: Hypnotherapy|BEHAVIORAL: Supportive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Care of the Dry Skin With Physiogel AI Lotion® (W0156)
Status: COMPLETED
Conditions: Eczema
Interventions: DRUG: Physiogel AI Lotion, Physiogel Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Polyethylene Glycolated IL-2 (PEG IL-2) Plus Zidovudine in HIV Positive, Asymptomatic and Symptomatic Individuals
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Interleukin-2, Polyethylene Glycolated|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Chronic Pain, Couples, & Physical Activity
Status: TERMINATED
Conditions: Chronic Pain|Fibromyalgia|Osteoarthritis, Knee|Osteoarthritis, Hip|Osteoarthritis|Ankylosing Spondylitis|Rheumatoid Arthritis|Chronic Low-back Pain|Chronic Shoulder Pain
Interventions: OTHER: No intervention, observational only.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Efficacy and Safety Study of GNR-068 (Ustekinumab Biosimilar) and Stelara® in the Treatment of Patients With Moderate to Severe Plaque Psoriasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Plaque Psoriasis
Interventions: BIOLOGICAL: GNR-068|BIOLOGICAL: Stelara®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate MET642 in Patients With NASH
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: MET642|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study
Status: RECRUITING
Conditions: HIV Infection|Tobacco-Related Carcinoma
Interventions: PROCEDURE: Computed Tomography|BEHAVIORAL: Smoking Cessation Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of EPI-743 in Patients With Friedreich's Ataxia
Status: COMPLETED
Conditions: Friedreich's Ataxia
Interventions: DRUG: Placebo|DRUG: EPI-743 400 mg|DRUG: EPI-743 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Mesh Implantation in Patients With Peritonitis for the Prevention of Incisional Hernia
Status: TERMINATED
Conditions: Peritonitis|Incisional Hernia|Surgery
Interventions: DEVICE: A non-absorbable composite mesh (Ethicon Physiomesh)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Study of Mavacamten in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)
Status: COMPLETED
Conditions: Non-obstructive Hypertrophic Cardiomyopathy
Interventions: DRUG: mavacamten|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, PK & PD Study of JTZ-951 in Anemic Subjects With End-stage Renal Disease
Status: COMPLETED
Conditions: Anemia of Chronic Kidney Disease
Interventions: DRUG: JTZ-951|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Potential of Probiotic Supplementation Sleep Quality
Status: RECRUITING
Conditions: Sleep Disorder|Anxiety|Depression|Stress|Probiotics
Interventions: DIETARY_SUPPLEMENT: heat-treated Limosilactobacillus fermentum|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Abdominal Binders on Patient's Wellbeing After Cesarean Delivery
Status: RECRUITING
Conditions: Effect of Abdominal Binders on Patient ( Pain, Quality of Recovery ) After Cesaean Section
Interventions: DEVICE: abdominal binder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tear Analysis by Isoelectric Focusing in Clinically Isolated Syndrome as Multiple Sclerosis Criterion
Status: COMPLETED
Conditions: Clinically Isolated Syndrome|Multiple Sclerosis
Interventions: PROCEDURE: tears and cerebrospinal fluid sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Trial for Inactivated Japanese Encephalitis Vaccine in Healthy Chinese Infants
Status: COMPLETED
Conditions: Encephalitis
Interventions: BIOLOGICAL: 0.5ml experimental vaccine on day 0,7 Vero cell-derived inactivated Japanese Encephalitis vaccine|BIOLOGICAL: 0.5ml experimental vaccine on day 0,28 Vero cell-derived inactivated Japanese Encephalitis vaccine|BIOLOGICAL: 0.5ml active comparator vaccine on day 0,7 inactivated freeze-dried Japanese Encephalitis vaccine(Vero cell)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Effect of Senna in Uremic Pruritus
Status: COMPLETED
Conditions: End Stage Renal Disease|Pruritus
Interventions: DRUG: Senna|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Upper Versus Lower Limb Exercises on Intermittent Claudication in Diabetic Patients
Status: COMPLETED
Conditions: Intermittent Claudication
Interventions: DEVICE: The arm crank ergometer|DEVICE: bicycle ergometer|DEVICE: treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fasting-mimicking Diet Combined With Traditional Chinese Medicine for Phlegm-dampness Type Obesity Patients
Status: UNKNOWN
Conditions: Obesity
Interventions: DEVICE: Fastening-mimicking diet combined with a "dispelling dampness" meal replacement|OTHER: Normal diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Tranexamic Acid and Modulating the Inflammatory Response in Sepsis
Status: RECRUITING
Conditions: Sepsis
Interventions: DRUG: Tranexamic acid|OTHER: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Esophagectomy and Chemoradiation for Patients With cN0-pT1b Stage Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Esophageal Cancer
Interventions: PROCEDURE: esophagectomy|COMBINATION_PRODUCT: chemoradiation|OTHER: active surveillance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Micro-osteo-perforations on the Rate of Alignment of Mandibular Anterior Teeth.
Status: UNKNOWN
Conditions: Orthodontics
Interventions: PROCEDURE: Microosteoperforations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical Study of BL-M07D1 in Locally Advanced or Metastatic Digestive Tract Tumors and Other Solid Tumors
Status: RECRUITING
Conditions: Locally Advanced or Metastatic Digestive Tract Tumors|Other Solid Tumors
Interventions: DRUG: BL-M07D1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photomotor Reflex to Evaluate the Role of the Non-visual Effects of Light in Neurological, Psychiatric and Ophthalmological Pathologies
Status: RECRUITING
Conditions: Sleep Disorders|Neurological Pathologies|Psychiatric Pathologies|Ophthalmological Pathologies
Interventions: OTHER: Specific light exposures
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intraventricular Drain Insertion: Comparison of Ultrasound-guided and Landmark-based Puncture of the Ventricular System
Status: TERMINATED
Conditions: Hydrocephalus|Intracranial Hypertension
Interventions: PROCEDURE: Ultrasound guided ventricular drain insertion|PROCEDURE: landmark-based ventricular drain insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Efficiency of Metreleptin Treatment for Patients With Multiple Symmetric Lipomatosis (MSL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Lipomatosis, Multiple Symmetrical
Interventions: DRUG: Metreleptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness and Safety of Slow Release Hydromorphone HCL for Treatment of Patients With Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Hip|Osteoarthritis, Knee
Interventions: DRUG: OROS hydromorphone HCI (slow release)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Donepezil on Speech Recognition in Cochlear Implant Users
Status: RECRUITING
Conditions: Bilateral Sensorineural Hearing Loss
Interventions: DRUG: Donepezil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy, Safety, and Tolerability Study of Canagliflozin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Canagliflozin 50 mg|DRUG: Placebo|DRUG: Canagliflozin 150 mg|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Clinical Efficacy of Bentonite Clay Gel on Bone Regeneration in the Treatment of Intra-bony Defects: A Clinico-radiograph Study
Status: RECRUITING
Conditions: Bone Regeneration
Interventions: OTHER: bentonite clay gel with hydroxyapatite
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of CellCept (Mycophenolate Mofetil) Versus Mycophenolate Sodium in Kidney Transplant Patients
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: MMF|DRUG: EC-MPS|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Unripe Carob Fruit in Celiac Patients
Status: NOT_YET_RECRUITING
Conditions: Celiac Disease
Interventions: DIETARY_SUPPLEMENT: Unripre Carob
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Telmisartan-Induced Reduction in Intra-Myocellular Lipids Trial
Status: COMPLETED
Conditions: Metabolic Syndrome X
Interventions: DRUG: Telmisartan (Micardis®) vs. Placebo|BEHAVIORAL: Low-Glycemic Index Diet vs. Control Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Aesthetic Restorations in Deciduous Anterior Teeth
Status: NOT_YET_RECRUITING
Conditions: Dental Caries in Children
Interventions: COMBINATION_PRODUCT: Restoration with resin composite and polyvinyl crown|PROCEDURE: Restoration with conventional resin composite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minimal Invasive Surgery Versus Interlaminar Decompression in Lumbar Canal Stenosis
Status: UNKNOWN
Conditions: Lumbar Spinal Stenosis
Interventions: PROCEDURE: minimally invasive surgery|PROCEDURE: conventional open surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of the UPLUG Device Onto the Infection Rate of Indwelling Central Venous Catheters in Patients Undergoing Chronic Hemodialysis
Status: TERMINATED
Conditions: Renal Disease, Chronic|Hemodialysis Catheter Infection
Interventions: DEVICE: Connecting valve system|DEVICE: Central haemodialysis Venous Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemoprevention of Anal Neoplasia Arising Secondary to Anogenital Human Papillomavirus Infection in Persons With HIV Infection.
Status: COMPLETED
Conditions: HIV Infections|Anus Neoplasms
Interventions: DRUG: Isotretinoin|DRUG: Interferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Anti-inflammatory Actions of Osteopathic Manipulative Treatment
Status: RECRUITING
Conditions: Inflammation
Interventions: PROCEDURE: Occipito-Atlantal Decompression (OA DC)|PROCEDURE: Sham Occipito-Atlantal Decompression (Sham OA DC)|PROCEDURE: Splenic Lymphatic Pump Technique (SpLPT)|PROCEDURE: Sham Splenic Lymphatic Pump Technique (Sham SpLPT)|DEVICE: Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)|DEVICE: Sham Transcutaneous Auricular Vagus Nerve Stimulation (Sham taVNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Safety and Efficacy of Oral Contrast Agent for Sonography
Status: COMPLETED
Conditions: Unspecified Disorder of Stomach and Duodenum
Interventions: DEVICE: KANG XIAN|DEVICE: TIAN XIA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: DLBS1033 for Acute NSTEMI Without Early Coronary Revascularization
Status: WITHDRAWN
Conditions: Acute Non-ST Elevation Myocardial Infarction
Interventions: DRUG: DLBS1033|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azithromycin Compared With Doxycycline for Treating Anorectal Chlamydia Trachomatis Infection Concomitant to a Vaginal Infection
Status: UNKNOWN
Conditions: Chlamydia Trachomatis Infection|Vaginal Infection|Anal Infection
Interventions: DRUG: azithromycin|DRUG: doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Intravenous Injection of SHR-1906 in the Treatment of Idiopathic Pulmonary Fibrosis
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: SHR-1906|DRUG: SHR-1906|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation and Immune Checkpoints Blockade in Metastatic NSCLC (BMS # CA209-632)
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer Metastatic
Interventions: DRUG: Ipilimumab|DRUG: Nivolumab|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation for the Treatment of Focal Hand Dystonia
Status: COMPLETED
Conditions: Dystonia, Focal, Task-specific
Interventions: DEVICE: rTMS|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paracervical Block During II-trimester Abortion
Status: COMPLETED
Conditions: Second Trimester Medical Abortion
Interventions: DRUG: bipuvacain|OTHER: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT