pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Multicenter, Cross-sectional Study on the Quality of Life in Long-term Survival Esophageal Cancer Patients After Radical Radiochemotherapy/Radiotherapy
Status: NOT_YET_RECRUITING
Conditions: Assessing the Current Quality of Life Status of Esophageal Cancer Patients Who Have Undergone Radical Chemoradiotherapy/Radiotherapy and Long-term Survival
Interventions: OTHER: questionnaire investigation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Single Dose Antenatal Betamethasone on Neonatal Respiratory Morbidity After Elective Cesarean
Status: UNKNOWN
Conditions: Respiratory Morbidity
Interventions: OTHER: Betamethasone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Participation in Competing Strategies for Colorectal Cancer Screening - a Randomized Health Services Study Within the National Screening Program in Poland
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: OTHER: Offering a choice for colorectal cancer screening|OTHER: Offering an alternative colorectal cancer screening method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Trace Elements in the Treatment of Endometriosis: a Pilot Study
Status: COMPLETED
Conditions: Endometriosis
Interventions: DIETARY_SUPPLEMENT: ENDO 1/ENDO 2|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Effect of Oral Semaglutide on the Pharmacokinetics of Furosemide and Rosuvastatin in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: Furosemide|DRUG: Rosuvastatin|DRUG: SNAC|DRUG: Semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Bioavailability Study of Carbidopa/Levodopa Extended-Release Tablets Under Fasting and Fed Conditions
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DRUG: WD-1603 Carbidopa-Levodopa Extended-Release Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neratinib in Combination With Ruxolitinib in Patients With mTNBC
Status: NOT_YET_RECRUITING
Conditions: Metastatic Triple-Negative Breast Carcinoma|Breast Cancer
Interventions: DRUG: Neratinib Oral Tablet|DRUG: Ruxolitinib Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: CPAP for the Treatment of Supine Hypertension
Status: RECRUITING
Conditions: Autonomic Failure|Pure Autonomic Failure|Multiple System Atrophy|Parkinson Disease|Supine Hypertension|Neurogenic Orthostatic Hypotension
Interventions: DEVICE: Active CPAP|DEVICE: Sham CPAP|OTHER: Sleeping in a head-up tilt (HUT) position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: BELotaxel(Docetaxel) and bellOXa(Oxaliplatin) in Advanced NSCLC
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Belotaxel|DRUG: Belloxa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Osteopathic Manipulative Treatment and Bio Electro-Magnetic Regulation Therapy on Low Back Pain in Adults.
Status: COMPLETED
Conditions: Musculoskeletal Pain
Interventions: DEVICE: Bio Electro-Magnetic Regulation (BEMER) Therapy|PROCEDURE: OMT (osteopathic manipulative treatment)|PROCEDURE: Light touch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparison Study of the Tensile Strength of Sutures Used in Dermatologic Surgery on the Day of Suture Removal, Following Wound Care With Two Different Products
Status: COMPLETED
Conditions: Sutured Wounds
Interventions: OTHER: Hydrogen peroxide|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Insulin Glargine/Lixisenatide Fixed Combination Versus Insulin Glargine Alone on Top of Metformin in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin glargine /lixisenatide Fixed Ratio Combination|DRUG: Insulin glargine|DRUG: Metformin (Background drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clofarabine Plus Low-Dose Cytarabine Induction and Decitabine Consolidation in Frontline Acute Myeloid Leukemia (AML) and High-Risk Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Clofarabine|DRUG: Cytarabine|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aflibercept Compared to Placebo in Term of Efficacy in Patients Treated With Gemcitabine for Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Neoplasm
Interventions: DRUG: Aflibercept (ziv-aflibercept, AVE0005, VEGF trap, ZALTRAP®)|DRUG: Placebo|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Community Reablement on Instrumental Activities of Daily Living in People With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: OTHER: RE-IADL|OTHER: General community rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Repetitive Transcranial Magnetic Stimulation (rTMS) Over the Brain on the Neurotransmitter Binding
Status: TERMINATED
Conditions: Stroke|Hemiplegia
Interventions: DEVICE: Low frequency rTMS|DEVICE: High frequency rTMS|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Best Antithrombotic Therapy in Patients With Acute Venous ThromboEmbolism While Taking Antiplatelets
Status: RECRUITING
Conditions: Venous Thromboembolic Disease
Interventions: DRUG: Full-dose anticoagulant therapy (AC)|DRUG: Antiplatelet therapy (AP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Vaginal Dinoprostone Prior to Abdominal Myomectomy
Status: UNKNOWN
Conditions: Myomectomy
Interventions: DRUG: Dinoprostone 3 mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Proximal- Versus Distal-Prioritized Robotic Practice Plus Kinetic Exergaming in Stroke Rehabilitation
Status: RECRUITING
Conditions: Stroke Rehabilitation
Interventions: OTHER: robotic practice|OTHER: kinetic exergaming|OTHER: conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prediction on Time to Death in Potential Controlled Donation After Circulatory Death (cDCD) Donors (DCD III Study)
Status: COMPLETED
Conditions: Tissue and Organ Procurement
Interventions: OTHER: No intervention wil be done. Patient characteristics and the standard care before and after withdrawal of life-sustaining treatment in all potential cDCD donors, will be studied. .
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nifedipine XL Versus Placebo for the Treatment of Preeclampsia With Severe Features During Induction of Labor
Status: COMPLETED
Conditions: Preeclampsia Severe
Interventions: DRUG: Nifedipine 30 MG|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improve Functional Health Status in Minority Women With HIV
Status: UNKNOWN
Conditions: HIV/AIDS
Interventions: BEHAVIORAL: Guided Imagery Intervention|BEHAVIORAL: Cognitive Power Intervention|BEHAVIORAL: Combined Guided Imagery and Cognitive Power Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Persuasion in Medicine: Experimental Evidence on Sender and Signal Effects
Status: COMPLETED
Conditions: Flu, Human|Influenza, Human|Covid19
Interventions: BEHAVIORAL: Video about safety and effectiveness of adult seasonal flu vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Multi-Omics to Predict the Blood Pressure Response to Antihypertensives
Status: RECRUITING
Conditions: Primary Hypertension
Interventions: DRUG: Amlodipine|DRUG: Olmesartan|DRUG: Hydrochlorothiazide|DRUG: Amlodipine/Olmesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Parental Insightfulness and the Acquisition of Social Skills in Children With ASD.
Status: UNKNOWN
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: PEERS® for Preschoolers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intralesional Antimony for Bolivian Cutaneous Leishmaniasis
Status: COMPLETED
Conditions: Leishmaniasis|Cutaneous Leishmaniasis
Interventions: DRUG: pentavalent antimony|PROCEDURE: cryotherapy|DRUG: placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Nano Fiber Reinforced Versus Conventional Nano Hybrid Composite in Restoring Premolars
Status: NOT_YET_RECRUITING
Conditions: Clinical Performance
Interventions: OTHER: NovaProTM Fill Universal Dental Composite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Efficacy of BBI-2000 in Treating and Preventing Contact Dermatitis
Status: COMPLETED
Conditions: Contact Dermatitis
Interventions: DRUG: BBI-2000|DRUG: Vehicle|OTHER: Multiple treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With High Cardiovascular Risk and Hypercholesterolemia (ODYSSEY COMBO I)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Placebo (for alirocumab)|DRUG: Alirocumab|DRUG: Lipid-Modifying Therapy (LMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Samarium Sm 153 Lexidronam Pentasodium and Bortezomib in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: bortezomib|OTHER: immunologic technique|RADIATION: samarium Sm 153 lexidronam pentasodium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Lifestyle Product on Physiological Measures and Subjective Well-being in Humans: A Systematic Study
Status: UNKNOWN
Conditions: Healthy Lifestyle
Interventions: DEVICE: Qi-Shield user group|DEVICE: Sham Qi-Shield user group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Evaluating the Safety and Immunogenicity of a Human Parainfluenza Type 3 (HPIV3) Virus Vaccine in Infants and Children
Status: COMPLETED
Conditions: Parainfluenza Virus 3, Human
Interventions: BIOLOGICAL: rHPIV3cp45 Vaccine|BIOLOGICAL: Placebo Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Does The Addition Of Divalproex Sodium ER To An Atypical Antipsychotic Drug (APD) Improve Cognition And Psychopathology In Outpatients With Schizophrenia (SCH) Or Schizoaffective Disorder (SAD)?
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: divalproex sodium ER|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of IgY (Antibody Against Pseudomonas) in Cystic Fibrosis Patients
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: IgY|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: 18F-DCFPyL Positron Emission Tomography (PET)/Computed Tomography (CT) in Men With Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms
Interventions: DRUG: 18F- DCFPyL PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Acupuncture in Treating Nerve Pain in Patients With Stage I, Stage II, or Stage III Breast Cancer Who Are Receiving Paclitaxel
Status: TERMINATED
Conditions: Breast Cancer|Stage I Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: OTHER: acupuncture therapy|OTHER: questionnaire administration|OTHER: management of therapy complications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: POPART'MUS: Prevention of Post Partum Relapses With Progestin and Estradiol in Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: DRUG: nomegestrol acetate|DRUG: estradiol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Clinical Trial Assessing Smoking Cessation Interventions In Dental Clinic Smokers
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Standard Care only|BEHAVIORAL: Dental Hygienist provided counseling + Brief Questionnaire|BEHAVIORAL: Dental Hygienist provided counseling with personalized risk communication + Brief Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Umbralisib and Rituximab as Initial Therapy for Patients With Follicular Lymphoma and Marginal Zone Lymphoma
Status: TERMINATED
Conditions: Lymphoma|Follicular Lymphoma|Follicular Lymphoma, Grade 1|Follicular Lymphoma Grade 2|Follicular Lymphoma Grade IIIa|Marginal Zone Lymphoma|Marginal Zone B Cell Lymphoma
Interventions: DRUG: Umbralisib|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Latency and Early Neonatal Provision of Antiretroviral Drugs Clinical Trial
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Nevirapine|DRUG: Zidovudine|DRUG: Lamivudine|DRUG: LPV/r
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Secondhand Smoke Respiratory Health Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Secondhand Smoke|Air Trapping|Tobacco|Airflow Limitation|Hyperinflation|Obstructive Lung Disease
Interventions: DRUG: Albuterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Niraparib in People With Soft Tissue Sarcoma Who Have Changes in Their Tumor DNA
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcoma,Soft Tissue|Sarcoma Uterus
Interventions: DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Recurrent Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: fowlpox virus vaccine vector|BIOLOGICAL: gp100 antigen
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the Combination Aliskiren (300 mg) and Hydrochlorothiazide (25mg) to Aliskiren (300mg) Monotherapy in Patients With Staged II Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Aliskiren/hydrochlorothiazide (HCTZ) (300/25 mg)|DRUG: Aliskiren (300 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FASTMAS (Fast-Fail Trials in Mood and Anxiety Spectrum Disorders) Kappa Opioid Receptor Phase 1 Study
Status: WITHDRAWN
Conditions: Anxiety Disorders
Interventions: DRUG: LY2456302
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pre-oxygenation With High-flow Nasal Cannula in Adults During Rapid Sequence Induction Anesthesia
Status: COMPLETED
Conditions: Anesthesia|Hypoxia|Surgery|Acute
Interventions: DEVICE: High flow transnasal oxygen|DEVICE: Pre oxygenation using tight fitting facemask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Subcutaneous Immunotherapy Towards Pollen in Children
Status: COMPLETED
Conditions: Rhinitis, Allergic|Conjunctivitis, Allergic|Asthma
Interventions: DRUG: Subcutaneous immunotherapy with ALK Alutard birch or ALK Alutard timothy|OTHER: No immunotherapy, symptomatic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Skin Irritation Potential of MOB015B in Healthy Subjects Using a Cumulative Irritant Patch Test Design
Status: COMPLETED
Conditions: Erythema
Interventions: DRUG: MOB015B|DRUG: 0.2% SLS|DRUG: 0.9% Saline|DRUG: MOB015B vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Measles-Rubella Vaccine Immunogenicity at 6 and 9 Months of Age
Status: COMPLETED
Conditions: Measles|Rubella|Rubella Syndrome, Congenital
Interventions: BIOLOGICAL: Measles-rubella (MR) vaccine at 6 and 9 months|BIOLOGICAL: Measles-rubella (MR) vaccine at 9 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Feasibility of RCT on the Efficacy of the Osteopathic Consultation in Computer Users
Status: COMPLETED
Conditions: Trapezius Muscle Strain
Interventions: OTHER: Osteopathic Consultation|OTHER: Sham Osteopathic Consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of CryoBalloon Focal Ablation System on Human Esophageal Barrett's Epithelium
Status: COMPLETED
Conditions: Barrett's Esophagus
Interventions: DEVICE: C2 CryoBalloon Focal Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Smoking Cessation Outcomes in Heavy Drinkers - 1
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: BEHAVIORAL: Standard treatment plus brief alcohol intervention|OTHER: Standard treatment (ST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Telmisartan/S-Amlodipine on 24-hour BP Control in Hypertensive Patients Inadequately Controlled
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: Telminuvo®Tab. 40/2.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of DS-9606a in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Cancer|Metastatic Cancer|Ovarian Cancer|Germ Cell Tumor
Interventions: DRUG: DS-9606a
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zevalin and Velcade in Relapsed/Refractory Mantle Cell Lymphoma
Status: TERMINATED
Conditions: Mantle-Cell Lymphoma
Interventions: DRUG: Rituximab, Bortezomib,Y90 ibritumomab tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Rivoceranib for Patients With Recurrent or Metastatic Olfactory Neuroblastoma
Status: NOT_YET_RECRUITING
Conditions: Metastatic Olfactory Neuroblastoma|Recurrent Olfactory Neuroblastoma
Interventions: DRUG: Rivoceranib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Efficacy of Over-the-counter Analgesics in the Prevention/Treatment of Transient Post-dose Symptoms Following Zoledronate Infusion in Post-menopausal Women
Status: COMPLETED
Conditions: Osteopenia
Interventions: DRUG: zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase 1/1b Dose Escalation Study Evaluating BSI-201 as a Single Agent and in Combination With Irinotecan in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Tumors
Interventions: DRUG: BSI-201 (iniparib)|DRUG: irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extended Resection for Rectal Cancer With Neoadjuvant Radiotherapy
Status: RECRUITING
Conditions: the Incidence of Complications Related to Rectal Anastomosis After Neoadjuvant Therapy
Interventions: PROCEDURE: extended resection with splenic flexure mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Model-informed Precision Dosing of Vancomycin in Adults
Status: COMPLETED
Conditions: Vancomycin
Interventions: DEVICE: Vancomycin model-informed precision dosing|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REmimazolam vs Propofol Total Intravenous Anesthesia on Outcomes After Major Noncardiac SurgEry
Status: RECRUITING
Conditions: Anesthesia|Surgery-Complications
Interventions: DRUG: Remimazolam|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Telehealth-enhanced Hybrid Cardiac Rehabilitation Among Acute Coronary Syndrome Survivors
Status: SUSPENDED
Conditions: Acute Coronary Syndrome|Myocardial Infarction
Interventions: BEHAVIORAL: Telehealth-enhanced Hybrid CR|BEHAVIORAL: Traditional CR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cognitive Behavioral Social Skills Training for Improving Social Functioning in People With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Cognitive Behavioral Social Skills Training (CBSST)|BEHAVIORAL: Goal-focused supportive contact (GFSC)|BEHAVIORAL: Social Skills Training|BEHAVIORAL: Goal Setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Painful Diabetic Neuropathy With Photon Stimulation
Status: COMPLETED
Conditions: Diabetic Neuropathy, Painful|Diabetic Neuralgia|Diabetic Polyneuropathy|Diabetic Mononeuropathy
Interventions: DEVICE: infrared light|DEVICE: infrared light; placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of the C-Tb Skin Test, When Given Intradermally to Healthy Volunteers Previously Vaccinated With BCG
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: C-Tb|BIOLOGICAL: 2 TU Tuberculin PPD RT 23 SSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A 3-Month Open-Label Safety and Efficacy Study of TNX-102 SL Tablets in Fibromyalgia Patients
Status: TERMINATED
Conditions: Primary Fibromyalgia
Interventions: DRUG: TNX-102 SL Tablet 2.8 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TVMR With the Innovalve System Trial - TWIST-BE TWIST-PILOT-BE
Status: WITHDRAWN
Conditions: Mitral Valve Regurgitation (Degenerative or Functional)
Interventions: DEVICE: Innovalve TMVR system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Tolerability, Safety and Pharmacokinetics of a New Drug
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: ACH15 50 mg|DRUG: ACH15 250 mg|DRUG: ACH15 500mg|DRUG: ACH15 - 1000mg|DRUG: ACH15 - 2000mg|DRUG: ACH15 - 500mg|DRUG: Placebo 250 mg|DRUG: Placebo 500mg|DRUG: Placebo 1000mg|DRUG: Placebo 2000mg|DRUG: Placebo 500mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Lidocaine Lubricant in Pediatric Urethral Catheterization
Status: COMPLETED
Conditions: Fevers|Pain
Interventions: PROCEDURE: Lubricant Instillation|DRUG: Lidocaine Lubricant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sugammadex vs Neostigmine/Glycopyrrolate on Urinary Retention After Spine Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Spine Surgery|Reversal of Neuromuscular Blockade|Urinary Retention Postoperative
Interventions: DRUG: Sugammadex|DRUG: Neostigmine|DRUG: Glycopyrrolate|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cigarette Consumption After switchinG to High or Low Nicotine strENght E-cigaretteS In Smokers With Schizophrenia
Status: RECRUITING
Conditions: Smoking|Schizophrenia Spectrum and Other Psychotic Disorders
Interventions: OTHER: JUUL E-CIGARETTE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study for the Pneumococcal Conjugate Vaccine V114 Versus Prevnar™ (V114-001)
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: Prevnar™|BIOLOGICAL: V114, Aluminum Adjuvanted|BIOLOGICAL: V114, Aluminum Nonadjuvanted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Study of LBH589 When Given in Combination With Lenalidomide and Dexamethasone in Adult Patients With Multiple Myeloma.
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: LBH589|COMBINATION_PRODUCT: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of ALT-BB4 to Determine Tolerance, Safety and Pharmacokinetics in Healthy Volunteer
Status: COMPLETED
Conditions: Health, Subjective
Interventions: DRUG: ALT-BB4|DRUG: 0.9%NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Fluid Resuscitation on Lactate in Traumatic Injury Patients
Status: NOT_YET_RECRUITING
Conditions: Fluid Resuscitation
Interventions: DRUG: 3% hypertonic Saline|DRUG: Ringer's lactated solution|DRUG: 0.9% Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy in Treating Patients With Retinoblastoma
Status: COMPLETED
Conditions: Retinoblastoma
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: mesna|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: QUALIOR Feasibility and Efficacy of a Supervised Home-based Standard Physical Exercise Program
Status: ACTIVE_NOT_RECRUITING
Conditions: Home Based Standardised Adapted Physical Activity Programme|Patients Taking Oral Targeted Therapy for Metastatic Cancer
Interventions: BEHAVIORAL: Supervised physical exercise programs|BEHAVIORAL: Adapted physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PET and MRI in the Follow-up of Neoadjuvant Chemotherapy of Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Fluoro-L-thymidine-(18F)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Regorafenib With Temozolomide With or Without RT in MGMT-Methylated, IDH Wild-type GBM Patients
Status: RECRUITING
Conditions: Glioblastoma, IDH-wildtype|MGMT-Methylated Glioblastoma
Interventions: DRUG: Regorafenib|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Polyherbal Supplement on the Signs and Symptoms of Delayed Onset Muscle Soreness
Status: COMPLETED
Conditions: Delayed Onset Muscle Soreness
Interventions: DIETARY_SUPPLEMENT: Polyherbal capsule|DIETARY_SUPPLEMENT: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: AirFLO2 Treatment for Hypoxia and/or Tachypnea in Patients With COVID-19
Status: TERMINATED
Conditions: Corona Virus Infection|Respiratory Rate|Hypoxia|Covid19
Interventions: DEVICE: AirFLO2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Versus Double Cryoballoon Ablation for Pulmonary Vein Isolation in Patients With Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: PVI by single cryoballoon application guided by Achieve Mapping Catheter|DEVICE: PVI by 2 routine cryoballoon applications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 16 Week Efficacy and 5 Year Long Term Efficacy, Safety and Tolerability of Secukinumab in Patients With Active Ankylosing Spondylitis
Status: COMPLETED
Conditions: Anklyosing Spondylitis
Interventions: DRUG: Secukinumab (75 mg)|DRUG: Placebo|DRUG: Secukinumab (150 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wheelchair Cushion Comparison Study: SAFETY
Status: COMPLETED
Conditions: Spinal Cord Injuries|Stroke|Healthy Adults
Interventions: DEVICE: Alternating air wheelchair cushion|DEVICE: Static air cushion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ATG-010(Selinexor) in Combination With Chemotherapy in RRMM
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Selinexor (80mg/d)|DRUG: Selinexor (100mg/d)|DRUG: Pegylated liposomal doxorubicin|DRUG: Dexamethasone|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alvimopan Use in Polytraumatized Patients
Status: TERMINATED
Conditions: Post Operative Ileus
Interventions: DRUG: Alvimopan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Motorised Probe Holder Assisting Prostate Biopsies
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DEVICE: Biopsies using Apollo and UroStation®|PROCEDURE: Biopsies using UroStation® (image fusion)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Emergency Department Management of Tobacco Use Disorder
Status: NOT_YET_RECRUITING
Conditions: Tobacco Use Disorder|Tobacco Use Cessation
Interventions: COMBINATION_PRODUCT: Nicotine Replacement Therapy Agent|OTHER: West Virginia Quit Line
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Percutaneous Peripheral Nerve Stimulation on Neck and Low Back Pain
Status: COMPLETED
Conditions: Neck Pain|Low Back Pain
Interventions: OTHER: Sensory Thresold, Burst High Frecuency|OTHER: Theta-Burst Stimulation|OTHER: Transcutaneous Electrical Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MLN9708 in Japanese Participants With Relapsed and/or Refractory Multiple Myeloma (RRMM)
Status: TERMINATED
Conditions: Relapsed and/or Refractory Multiple Myeloma
Interventions: DRUG: Ixazomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination or Sequence of Vemurafenib, Cobimetinib, and Atezolizumab in High-risk, Resectable Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: DRUG: Cobimetinib 20 MG Oral Tablet|DRUG: Vemurafenib 240 Mg Oral Capsule|DRUG: Atezolizumab 1200 MG in 20 ML Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictors of Post-alteplase Hemorrhagic Transformation of Brain Infarction
Status: RECRUITING
Conditions: Ischemic Stroke|Alteplase Adverse Reaction
Interventions: DRUG: Alteplase|DRUG: Alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics, and Pharmacodynamics of NBI-98854 in Children and Adolescents With Tourette Syndrome
Status: COMPLETED
Conditions: Tourette Syndrome
Interventions: DRUG: NBI-98854
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Ottobock Helmet Therapy in Infants With Plagiocephaly, Brachycephaly or Combination of Both
Status: COMPLETED
Conditions: Plagiocephaly, Positional|Plagiocephaly, Nonsynostotic|Brachycephaly
Interventions: DEVICE: Ottobock helmet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Epigenetic Reprogramming in Relapse AML
Status: TERMINATED
Conditions: Leukemia, Acute Myeloid
Interventions: DRUG: Decitabine|DRUG: Vorinostat|DRUG: Fludarabine|DRUG: Cytarabine|DRUG: Filgrastim|DRUG: Cytarabine|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Efficacy of the VRC01 Antibody in Reducing Acquisition of HIV-1 Infection Among Men and Transgender Persons Who Have Sex With Men
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: VRC01|BIOLOGICAL: Placebo for VRC01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treating Impulsivity in Adults With Probiotics
Status: COMPLETED
Conditions: Impulsive Behavior|Compulsive Disorder|ADHD|Borderline Personality Disorder
Interventions: DIETARY_SUPPLEMENT: Treatment with a probiotic|OTHER: Treatment with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2/3 Study to Evaluate PK, Safety & Efficacy of INM004 in STEC Positive Pediatric Patients for Prevention of HUS
Status: TERMINATED
Conditions: Bloody Diarrhea|STEC, Unspecified|Hemolytic-Uremic Syndrome|Pediatric Kidney Disease
Interventions: DRUG: INM004|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Silkworm Pupa Tablets in Gastrointestinal Malignancies at Nutritional Risk Following Radical Surgery
Status: RECRUITING
Conditions: Nutritional Deficiency|Gastrointestinal Cancer|Frailty Syndrome
Interventions: DIETARY_SUPPLEMENT: Silkworm pupa tablets|DIETARY_SUPPLEMENT: Control product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Prebiotics on Gut Bacterial Parameters, Immune Function & Exercise-Induced Airway Inflammation.
Status: COMPLETED
Conditions: Exercised Induced Asthma|Asthma
Interventions: DIETARY_SUPPLEMENT: HOST-DM059|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Foot Structures on Plantar Fasciitis and Therapeutic Footwear Intervention
Status: UNKNOWN
Conditions: Fasciitis
Interventions: PROCEDURE: Foot orthosis, footwear|PROCEDURE: Foot orthosis, Footwear|PROCEDURE: Foot orthosis, footwear
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mechanistic Study of Subclinical Hypothyroidism In the Elderly
Status: COMPLETED
Conditions: Subclinical Hypothyroidism
Interventions: DRUG: Levothyroxine|DRUG: Liothyronine|DRUG: Thyrotropin-Releasing Hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Clinical Trial of Transtek Body Fat Analyzer (GBF-1251-B & Other 3 Models)
Status: COMPLETED
Conditions: Weight|Body Fat Disorder|Bone Mass
Interventions: DEVICE: Transtek 125X|DEVICE: Transtek 950D
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose:
Clinical trial: D-Cycloserine and Social Skills Training in Autism Spectrum Disorders
Status: COMPLETED
Conditions: Autistic Disorder|Asperger's Disorder|Pervasive Developmental Disorder NOS
Interventions: DRUG: D-cycloserine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Cilostazol and Probucol Alone and in Combination on Atherosclerosis Related Biomarker---atherosclerosis Cerebral Infarction Patient as Study Subject
Status: COMPLETED
Conditions: Atherosclerosis Cerebral Infarction
Interventions: DRUG: Cilostazol group|DRUG: Probucol group|DRUG: Cilostazol + Probucol group|DRUG: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Inclisiran as Monotherapy in Patients With Primary Hypercholesterolemia Not Receiving Lipid-lowering Therapy.
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Inclisiran|DRUG: Ezetimibe|DRUG: Matching Placebo for Inclisiran|DRUG: Matching Placebo for Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safer Use of Antipsychotics in Youth
Status: COMPLETED
Conditions: Child Behavior Disorders
Interventions: OTHER: Control - Provider Medication Alert Only|OTHER: Intervention - Alert + CAP Review AND Enhanced BH Access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: PET/CT Imaging of uPAR-expression in Patients With Neuroendocrine Tumors Using 68Ga-NOTA-AE105
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: One injection of 68Ga-NOTA-AE105|DEVICE: PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Stacking Exercises Aid the Decline in FVC and Sick Time
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DEVICE: Lung Volume Recruitment (LVR)|OTHER: Conventional Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short Term Results of Tele-Rehabilitation
Status: COMPLETED
Conditions: COVID-19|Dyspnea
Interventions: OTHER: Tele-rehabillitation|OTHER: Prescribed Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diode Low-power Laser Before In-office Bleaching
Status: COMPLETED
Conditions: Tooth Sensitivity
Interventions: DEVICE: Low-level laser treatment|OTHER: tooth bleaching procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Preventing Functional Decline in Acutely Hospitalized Older Patients (PREV_FUNC) Study
Status: RECRUITING
Conditions: Hospitalization|Older Adults
Interventions: OTHER: Intervention 1 (simple exercise program)|OTHER: Intervention 2 (comprehensive exercise program)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness and Cost-effectiveness of the Initial Medication Adherence Intervention
Status: ACTIVE_NOT_RECRUITING
Conditions: Adherence, Medication
Interventions: BEHAVIORAL: Initial Medication Adherence (IMA)|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Combination of Radiotherapy, Chemotherapy and Immunotherapy in High-Risk Localized Soft Tissue Sarcoma
Status: RECRUITING
Conditions: High-Risk Localized Soft Tissue Sarcoma
Interventions: DRUG: Pegylated Liposomal Doxorubicin|DRUG: Doxorubicin|DRUG: Anti-PD-1 monoclonal antibody|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Biopsy Technique on Moleculargenetic Tumor Characterisation in NSCLC
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung|Pathology, Molecular
Interventions: PROCEDURE: Forceps biopsy|PROCEDURE: Cryobiopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Upper Extremity Function in Multiple Sclerosis Patients With Advanced Disability Treated With Ocrevus
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis|Pathologic Processes|Demyelinating Diseases|Nervous System Diseases|Autoimmune Diseases|Immune System Diseases|Primary Progressive Multiple Sclerosis|Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: Ocrelizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of Liquid Stable Levothyroxine in Trisomy 21 Pediatric Patients
Status: TERMINATED
Conditions: Hypothyroidism|Trisomy 21
Interventions: DRUG: Liquid stable levothyroxine (L-T4) Tirosint-SOL|DRUG: Oral tablet levothyroxine (L-T4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER