pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Docetaxel, Capecitabine and Oxaliplatin in Advanced Stomach Cancer
Status: COMPLETED
Conditions: Stomach Cancer
Interventions: DRUG: Docetaxel, Capecitabine and Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo-Controlled Randomized Study of KW-3902 for Subjects Hospitalized With Worsening Renal Function and Heart Failure Requiring IV Therapy
Status: COMPLETED
Conditions: Heart Failure, Congestive
Interventions: DRUG: rolofylline|DRUG: Comparator: Placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Adipose-Derived Stem Cells to Treat Complex Perianal Fistulas Patients With Crohn's Disease
Status: TERMINATED
Conditions: Complex Perianal Fistula|Crohn Disease
Interventions: DRUG: Expanded autologous adipose-derived adult stem cells (eASCs)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|Brain Glioblastoma|Estrogen Receptor Negative|Extensive Stage Small Cell Lung Carcinoma|Head and Neck Carcinoma|HER2/Neu Negative|Hormone-Resistant Prostate Cancer|Limited Stage Small Cell Lung Carcinoma|Myelodysplastic Syndrome|Progesterone Receptor Negative|Progressive Disease|Recurrent Carcinoma|Stage II Pancreatic Cancer|Stage II Rectal Cancer|Stage IIA Pancreatic Cancer|Stage IIA Rectal Cancer|Stage IIB Pancreatic Cancer|Stage IIB Rectal Cancer|Stage IIC Rectal Cancer|Stage III Colon Cancer|Stage III Esophageal Cancer|Stage III Gastric Cancer|Stage III Non-Small Cell Lung Cancer|Stage III Ovarian Cancer|Stage III Pancreatic Cancer|Stage III Rectal Cancer|Stage III Skin Melanoma|Stage IIIA Colon Cancer|Stage IIIA Esophageal Cancer|Stage IIIA Gastric Cancer|Stage IIIA Non-Small Cell Lung Cancer|Stage IIIA Ovarian Cancer|Stage IIIA Rectal Cancer|Stage IIIA Skin Melanoma|Stage IIIB Colon Cancer|Stage IIIB Esophageal Cancer|Stage IIIB Gastric Cancer|Stage IIIB Non-Small Cell Lung Cancer|Stage IIIB Ovarian Cancer|Stage IIIB Rectal Cancer|Stage IIIB Skin Melanoma|Stage IIIC Colon Cancer|Stage IIIC Esophageal Cancer|Stage IIIC Gastric Cancer|Stage IIIC Ovarian Cancer|Stage IIIC Rectal Cancer|Stage IIIC Skin Melanoma|Stage IV Bladder Cancer|Stage IV Bone Sarcoma|Stage IV Breast Cancer|Stage IV Colon Cancer|Stage IV Esophageal Cancer|Stage IV Gastric Cancer|Stage IV Non-Small Cell Lung Cancer|Stage IV Ovarian Cancer|Stage IV Pancreatic Cancer|Stage IV Rectal Cancer|Stage IV Renal Cell Cancer|Stage IV Skin Melanoma|Stage IV Soft Tissue Sarcoma|Stage IVA Bone Sarcoma|Stage IVA Colon Cancer|Stage IVA Rectal Cancer|Stage IVB Bone Sarcoma|Stage IVB Colon Cancer|Stage IVB Rectal Cancer|Triple-Negative Breast Carcinoma
Interventions: OTHER: Best Practice|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Supportive Care|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Expanded Use of G-CSF Mobilized Donor CD34+ Selected Cells for Allogeneic Transplantation
Status: NO_LONGER_AVAILABLE
Conditions: Chronic Myeloid Leukemia|Myelodysplastic Syndrome|Acute Myeloid Leukemia
Interventions: BIOLOGICAL: G-CSF mobilized CD34+ selected cells for transplantation
Study Type: EXPANDED_ACCESS
Clinical trial: evaluatioN de la perfOrMAnce De Capteurs E-textiles
Status: UNKNOWN
Conditions: Healthy Volunteers Without Any Cardiac or Any Neurological Disorders
Interventions: DEVICE: CARDIOSKIN - Short record|DEVICE: Cardioskin - long record|DEVICE: Neuronaute - long record|DEVICE: Neuronaute -short record
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Addition of Dexmedetomidine to Ropivacaine-induced Supraclavicular Block (ADRIB Trial)
Status: COMPLETED
Conditions: Radius Fractures|Ulna Fractures|Hand Injuries|Wrist Injuries|Forearm Injuries
Interventions: DRUG: Ropivacaine|DRUG: Ropivacaine + Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pregabalin on Interleukin-6 Levels in Living Donor Kidney
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Polyunsaturated Fatty Acids in Children and Adolescents With Attention Deficit/ Hyperactivity Disorder
Status: TERMINATED
Conditions: ADHD
Interventions: DIETARY_SUPPLEMENT: ω-3 fatty acids suspension|DIETARY_SUPPLEMENT: placebo suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation in Patients With Neuropathic Pain and Depression.
Status: RECRUITING
Conditions: Neuropathic Pain|Depression
Interventions: DEVICE: Repetitive transcranial magnetic stimulation (rTMS) - M1/DLPFC|DEVICE: Repetitive transcranial magnetic stimulation (rTMS) - DLPFC/M1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Plasmapheresis on Clinical Improvement and Biological Parameters of Patients With Long-haul COVID
Status: WITHDRAWN
Conditions: Long-Haul COVID-19
Interventions: DRUG: Plasmapheresis|OTHER: Blood collection|OTHER: Stool samples|OTHER: PET scan|OTHER: Cycle ergometer stress test|OTHER: Questionnaires at baseline|OTHER: Medical consultations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
Status: RECRUITING
Conditions: Chronic Pain|Acute Pain|Post Operative Pain|Fibromyalgia, Primary|Fibromyalgia, Secondary|Fibromyalgia|Irritable Bowel Syndrome|Chronic Headache Disorder|Chronic Migraine|Chronic Pelvic Pain Syndrome|Temporomandibular Joint Disorders|Endometriosis-related Pain|Arthritis|Chronic Low-back Pain|Failed Back Surgery Syndrome|Post Herpetic Neuralgia|Neuropathic Pain|Painful Diabetic Neuropathy|Painful Bladder Syndrome|Trauma-related Wound|Trauma, Multiple|Chronic Pain Syndrome|Chronic Shoulder Pain
Interventions: DEVICE: SOMA pain manager smartphone application
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Tolerability of Intravenous Dose of MEDI-546 in Japanese Subjects With Systemic Lupus Erythematosus.
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: MEDI-546|DRUG: MEDI-546|DRUG: MEDI-546
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Energy and Physical Density Manipulation on Appetite
Status: COMPLETED
Conditions: Appetite|Eating Behavior
Interventions: OTHER: LPD+LED|OTHER: HPD+LED|OTHER: LPD+HED|OTHER: HPD+HED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Efficacy and Safety Study of Anlotinib Hydrochloride Capsule Combined With Chemotherapy Versus Placebo Combined With Chemotherapy as First-line Treatment in Subjects With Advanced Non-squamous Cell Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Advanced Non-squamous Cell Non-small Cell Lung Cancer
Interventions: DRUG: Anlotinib hydrochloride capsule|DRUG: Carboplatin injection|DRUG: Pemetrexed disodium f Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Residual Capacity (FRC) Guided Alveolar Recruitment Strategy
Status: COMPLETED
Conditions: Ventilation|Functional Residual Capacity
Interventions: PROCEDURE: Alveolar recruitment manoeuvre
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of an Antioxidant-Enriched Multivitamin Supplement on Inflammation and Oxidative Stress in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: AquADEKs-2|DIETARY_SUPPLEMENT: control multivitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Use of Sterile Transparent Film Dressing in Newborns
Status: COMPLETED
Conditions: Newborn|Peripheral Venous Catheterization
Interventions: OTHER: Use of sterile transparent film dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clarithromycin as Immunomodulator for the Management of Sepsis
Status: COMPLETED
Conditions: Sepsis|Severe Sepsis|Septic Shock
Interventions: DRUG: Clarithromycin|DRUG: Dextrose 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Clinical Activity of QEL-001 in A2-mismatch Liver Transplant Patients
Status: RECRUITING
Conditions: Rejection; Transplant, Liver|Liver Failure|Liver Diseases
Interventions: DRUG: QEL-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiopulmonary Training in the Victims With Multiple Morbidities by Application of Novel Heart Rate Sensing Clothes
Status: RECRUITING
Conditions: Degeneration Muscle|Multiple Morbidities|Heart; Complications
Interventions: DEVICE: E-clothes|BEHAVIORAL: Healthy consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Changes in Cerebral Blood Flow With Spinal Manipulative Therapy vs. Voluntary Motion
Status: UNKNOWN
Conditions: Vertebral Artery Dissection|Cerebrovascular Accident|Cerebrovascular Stroke
Interventions: OTHER: head positions and spinal manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Validation of Stroke Volume Measurement by a New Noninvasive Hemodynamic Monitoring System (NexFin)in Comparison to Different Invasive Procedures as Picco2, FloTrac and TEE
Status: COMPLETED
Conditions: Stroke Volume|Mean Arterial Pressure
Interventions: DEVICE: NexFin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dicloxacillin: Clinical Relevance of Drug-drug Interactions by Induction of Drug Metabolism.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dicloxacillin|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using CBT to Probe Psychobiobehavioral Resilience to Post-trauma Psychopathology
Status: COMPLETED
Conditions: Anxiety|Depression
Interventions: BEHAVIORAL: Healthy Mind Intervention (HMI)|BEHAVIORAL: Healthy Body Intervention (HBI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bortezomib, Melphalan, and Total-Body Irradiation Before Stem Cell Transplant in Treating Patients With Multiple Myeloma
Status: COMPLETED
Conditions: DS Stage I Plasma Cell Myeloma|DS Stage II Plasma Cell Myeloma|DS Stage III Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: DRUG: Bortezomib|RADIATION: Total-Body Irradiation|DRUG: Melphalan|PROCEDURE: Autologous Bone Marrow Transplantation|PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|PROCEDURE: Peripheral Blood Stem Cell Transplantation|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Hepatoma Treated by Perfusing Cinobufacin Through Hepatic Artery Combining Embolotherapy
Status: UNKNOWN
Conditions: Hepatoma|Cinobufacin Injection
Interventions: DRUG: Cinobufacin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Automated Oxygen Titration With O2matic Home Oxygen Therapy (O2matic HOT) Phase 1
Status: TERMINATED
Conditions: COPD|Chronic Hypoxemic Respiratory Failure
Interventions: DEVICE: O2matic HOT|DEVICE: Oxygen concentrator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Glycemic Effects, Safety, and Tolerability of Exenatide Once Weekly in Subjects With Type 2 Diabetes Mellitus (DURATION-5)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: exenatide once weekly|DRUG: exenatide twice daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Isoquercetin (IQC-950AN) Plus Standard of Care Versus Standard of Care Only for the Treatment of COVID-19
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Isoquercetin (IQC-950AN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicentric Randomised Trial for Resectable Gastric Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Docetaxel|DRUG: Oxaliplatin|DRUG: Capecitabine|PROCEDURE: gastrectomy|RADIATION: radiotherapy of gastric cancer|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Assessment of the Right Ventricle Using Pressure-volume Loop Catheter and Pulmonary Artery Catheter in Patients Undergoing Left Ventricular Assist Device Placement
Status: RECRUITING
Conditions: Right Ventricular Dysfunction
Interventions: DIAGNOSTIC_TEST: Hemodynamic assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1 Study in Participants With Advanced Cancer
Status: COMPLETED
Conditions: Advanced Cancer|Squamous Cell Carcinoma|Carcinoma, Squamous Cell of Head and Neck|Lung Squamous Cell Carcinoma Stage IV|Anal Squamous Cell Carcinoma|Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Prexasertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Journey of Patients With Vasculitis From First Symptom to Diagnosis
Status: COMPLETED
Conditions: Vasculitis|Systemic Vasculitis|Behcet's Disease|CNS Vasculitis|Cryoglobulinemic Vasculitis|Eosinophilic Granulomatous Vasculitis|Temporal Arteritis|Giant Cell Arteritis|Granulomatosis With Polyangiitis|Wegener Granulomatosis|Henoch Schonlein Purpura|IgA Vasculitis|Microscopic Polyangiitis|Polyarteritis Nodosa|Takayasu Arteritis|Urticarial Vasculitis
Interventions: OTHER: Online Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Valganciclovir to Reduce T Cell Activation in HIV Infection
Status: COMPLETED
Conditions: HIV Infections|Cytomegalovirus Infections
Interventions: DRUG: Valganciclovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vactosertib With Durvalumab in Urothelial Carcinoma Failing Checkpoint Inhibition
Status: NOT_YET_RECRUITING
Conditions: Urothelial Carcinoma Recurrent|Advanced Urothelial Carcinoma
Interventions: DRUG: Vactosertib(TEW-7197)/ Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Factors Affecting Therapeutic Efficacy of Vaginal Laser Therapy for Female Stress Urinary Incontinence, and the Effect of Vaginal Laser Therapy on Overactive Bladder Syndrome and Sexual Function
Status: RECRUITING
Conditions: Laser Thermotherapy, Stress Urinary Incontinence
Interventions: PROCEDURE: Vaginal laser thermotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bortezomib and Pembrolizumab With or Without Pelareorep for the Treatment of Relapsed or Refractory Multiple Myeloma, AMBUSH Trial
Status: RECRUITING
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: DRUG: Bortezomib|DRUG: Dexamethasone|BIOLOGICAL: Pelareorep|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immune Response of Increasing Doses of OVX836 After Intramuscular or Intranasal Administrations in Healthy Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: OVX836 (Intramuscular)|BIOLOGICAL: Placebo (Intramuscular)|BIOLOGICAL: OVX836 (Intranasal)|BIOLOGICAL: Placebo (Intranasal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bowel Preparation May Lead to a Higher Feasibility of Intestinal Infection
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: 2L of polyethyleneglycol|DIETARY_SUPPLEMENT: inulin|COMBINATION_PRODUCT: probiotic combination product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Combination of Palbociclib With ddEC-P as Neoadjuvant Therapy in Triple Negative Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Breast Diseases|Breast Neoplasms
Interventions: DRUG: Palbociclib|DRUG: Placebo oral capsule|DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Oral Fispemifene for the Treatment of Sexual Dysfunction in Hypogonadal Men
Status: UNKNOWN
Conditions: Secondary Hypogonadism|Sexual Dysfunction|Erectile Dysfunction
Interventions: DRUG: fispemifene|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Supplementation Therapy in Autism and Response to Treatment Study
Status: RECRUITING
Conditions: Autism|Autism Spectrum Disorder|Autism Spectrum Disorder High-Functioning|Asperger Syndrome|Depressive Symptoms|Anxiety State
Interventions: DIETARY_SUPPLEMENT: Oral Ultramicronized-Palmitoylethanolamide (um-PEA; 600 mg per day) in tablet form
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palonosetron Versus Ondansetron for PONV Prevention in Patients Undergoing ERCP
Status: UNKNOWN
Conditions: Antiemetic|Postoperative Nausea and Vomiting
Interventions: DRUG: Ondansetron 4 mg|DRUG: Palonosetron 75 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Olfactive Discriminative Ability of Dogs When Confronted With Seizure and Non-seizure Samples // Identification of Potential Biomarkers for Epilepsy in Human Sweat.
Status: TERMINATED
Conditions: Epilepsy
Interventions: OTHER: Planned Sweat collection|OTHER: Spontaneous Sweat collection|OTHER: Healthy volunteers sweat collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating Benefits of Hearing Aid Microphone Directionality Technologies
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Phonak Audeo hearing aid|DEVICE: Phonak hearing aid with multiple directionality settings, adjustable via a mobile app
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety, Tolerability and Analgesic Efficacy of Multiple Doses of Ketorolac Tromethamine (IN) for Postoperative Pain
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Ketorolac tromethamine|DRUG: Ketorolac tromethamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of Comprehensive Stroke Rehabilitation Therapy for Enhanced Quality of Life
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Experimental Group, Sub-Acute|OTHER: Experimental Group, Chronic|OTHER: Standard of Care, Sub-Acute|OTHER: Standard of Care, Chronic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Active Breathing Exercises on Respiratory Rhythm Disorders in Stroke Patients
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: BEHAVIORAL: Rehabilitation training|BEHAVIORAL: Active Breathing Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LEA29Y (Belatacept) Emory Edmonton Protocol
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: BIOLOGICAL: Allogeneic Pancreatic Islet Cells|BIOLOGICAL: Belatacept|BIOLOGICAL: Basiliximab|DRUG: Mycophenolate Mofetil|DRUG: Tacrolimus|PROCEDURE: Intraportal infusion of islet cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b/2 Study of PLX3397 + Radiation Therapy + Temozolomide in Patients With Newly Diagnosed Glioblastoma
Status: COMPLETED
Conditions: Patients With Newly Diagnosed Glioblastoma
Interventions: DRUG: PLX3397|RADIATION: Radiation Therapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Application of Probe Confocal Laser Endomicroscopy in Pancreatic Tumor Surgery
Status: RECRUITING
Conditions: Pancreatic Cancer|Diagnosis|Pancreatoduodenectomy|Distal Pancreatectomy
Interventions: DEVICE: probe confocal laser endomicroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Drug Study In Women With Refractory Metastatic Breast Cancer After First-line or Second-line Herceptin.
Status: COMPLETED
Conditions: Metastatic Breast Cancer|Neoplasms, Breast
Interventions: DRUG: Investigational Cancer Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telemedicine Follow-up for Routine, Low-Risk Oculoplastic Surgery
Status: UNKNOWN
Conditions: Eyelid Diseases|Ptosis, Eyelid|Blepharoptosis|Dermatochalasis|Ectropion|Entropion|Eyelid Tumor|Skin Cancer, Eyelid|Floppy Eyelid Syndrome
Interventions: OTHER: Telemedicine follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Mechanism of Mindfulness-Based Online Intervention in Enhancing Cognitive Flexibility
Status: ACTIVE_NOT_RECRUITING
Conditions: Emotional Distress
Interventions: BEHAVIORAL: Internet-based Mindfulness Intervention for Emotional Distress (iMIED)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Lumbar Stabilization Exercise on Transversus Abdominis Muscle Activation Capacity and Function in Chronic Low Back Pain Patients
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: OTHER: lumbar stabilization exercise|OTHER: trunk muscle strengthening exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine if Caffeine Accelerates Emergence From Propofol Anesthesia
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Placebo|DRUG: Caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Minimum Effective Dose of Ropivacaine for Spinal Anesthesia for Cesarean Delivery
Status: COMPLETED
Conditions: Spinal Anesthesia
Interventions: PROCEDURE: Intervertebral space|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Interplay Between Obstructive Sleep Apnea Cognitive Dysfunction in Pediatric Patients
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: PROCEDURE: adenotonsillectomy|BEHAVIORAL: Lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Patients With Wet Age-related Macular Degeneration or Diabetic Macular Edema to Assess the freQuency of Use of Intravitreal Aflibercept in Routine Clinical Practices in Latin America
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: Eylea (Aflibercept, VEGF Trap-Eye, BAY86-5321)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Trial to Evaluate Safety and Efficacy of GM-CSF/Sargramostim in Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: Sargramostim|DRUG: Saline - placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cortical Excitability and Treatment Response in People With Epilepsy
Status: ACTIVE_NOT_RECRUITING
Conditions: Epilepsy
Interventions: DEVICE: Eyes-closed rest-EEG registration|DEVICE: Transcranial Magnetic Stimulation during EEG and EMG registrations|DEVICE: Photic stimulation during eyes-closes EEG registration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluate the Efficacy and Safety of Different Doses of Edaravone Dexborneol Concentrated Solution for Injection Combined With Conventional Medical Therapy in the Treatment of Patients With Cerebral Hemorrhage
Status: RECRUITING
Conditions: Subjects With Cerebral Hemorrhage
Interventions: DRUG: Synbixin/Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Translingual Neurostimulation for the Virtual Treatment of Post-Traumatic Stress Disorder: A Feasibility Pilot
Status: COMPLETED
Conditions: Post-traumatic Stress Disorder
Interventions: DEVICE: Translingual neurostimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel in Treating Patients With Recurrent or Refractory Germ Cell Cancer
Status: COMPLETED
Conditions: Extragonadal Germ Cell Tumor|Ovarian Cancer|Testicular Germ Cell Tumor
Interventions: DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: IMMUNOtherapy and Stereotactic ABlative Radiotherapy (IMMUNOSABR) a Phase II Study
Status: ACTIVE_NOT_RECRUITING
Conditions: NSCLC Stage IV|Metastatic Disease
Interventions: DRUG: Darleukin|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Thiamphenicol on EAAT2 and Other Biomarkers From Nasal Biopsied Tissue
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Thiamphenicol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ulnar Artery Versus Radial Artery Cannulation in Paediatric Patients
Status: RECRUITING
Conditions: Arterial Catheterization
Interventions: PROCEDURE: Ulnar artery cannulation|PROCEDURE: Radial artery cannulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Preparing for Eating Disorders Treatment Through Compassionate Letter-Writing
Status: ENROLLING_BY_INVITATION
Conditions: Eating Disorders|Anorexia Nervosa|Bulimia Nervosa|Binge-Eating Disorder|Compassion
Interventions: OTHER: Self-compassionate letter-writing intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Two Devices for Taking Measurements of the Eye to Assist in Lens Selection for Cataract Surgery
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: GALILEI G6 Lens Professional|DEVICE: Oculus Pentacam AXL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Comparison of Changes of QTc, Tp-e Interval, and Tp-e/QT Ratio, Tp-e/QTc Ratio on the ECG During Robotic-assisted Laparoscopic Radical Prostatectomy Under Sevoflurane, Desflurane and Total Intravenous Anesthesia -Randomized Controlled Trial
Status: COMPLETED
Conditions: Robotic-assisted Laparoscopic Radical Prostatectomy
Interventions: DRUG: sevoflurane|DRUG: desflurane|DRUG: propofol and remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: STOP-T1D Low-Dose (ATG)
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Antithymocyte Globulin|DRUG: Placebo (for ATG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I/II GVHD Prevention Trial Combining Pacritinib With Sirolimus-Based Immune Suppression
Status: COMPLETED
Conditions: Graft Vs Host Disease|GVHD
Interventions: DRUG: Pacritinib|DRUG: Sirolimus|DRUG: Tacrolimus|PROCEDURE: Allogenic hematopoietic cell transplant (alloHCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Effect of RO4607381 in Patients With Relatively Low Levels of High Density Lipoprotein-Cholesterol (HDL-C)
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: Placebo|DRUG: Pravastatin|DRUG: Dalcetrapib|DRUG: Dalcetrapib|DRUG: Dalcetrapib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ancillary Study of Methylation Biomarkers in a Randomized Controlled Trial of a Personalized Prevention of Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DIETARY_SUPPLEMENT: Magnesium glycinate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Avastin (Bevacizumab) in Combination With Standard Therapy in Patients With Metastatic Renal Cell Cancer.
Status: COMPLETED
Conditions: Renal Cell Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: Interferon alfa-2a|DRUG: Vinblastine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Physical Performance Before and After Intervention and Birth Outcome in Pregnant Somali and Swedish Women
Status: COMPLETED
Conditions: Muscle Weakness|Vitamin D Deficiency
Interventions: DRUG: 1 combination tablet of Vitamin D3/calcium per day|DRUG: 2 combination tablets of Vitamin D3/calcium per day
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Myobloc in the Treatment of Sialorrhea (Drooling) in Patients With Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis|Sialorrhea
Interventions: DRUG: Botulinum toxin type B (Myobloc)|PROCEDURE: Injection of salivary glands
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: EvAluation of Clinical Effectiveness Of RoLenium Administered With Elpenhaler in Chronic Obstructive Pulmonary Disease (COPD) patientS in Daily Clinical Practice, in Greece
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: COPD Pharmacologic Substance
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Biomarkers and Molecular Mechanism Study of Hepatocellular Carcinoma After Radical Resection and Conversion Therapy
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DIAGNOSTIC_TEST: ctDNA monitoring|DIAGNOSTIC_TEST: Plasma proteomic analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Grain Moxibustion Treatment on Insomnia: a Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: DEVICE: Grain moxibustion|DEVICE: Sham grain moxibustion|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Dose Vitamin D Supplementation in Children With Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease|Vitamin D Deficiency|Health Related Quality of Life|Hand Grip Strength|Bone Mineral Density
Interventions: DRUG: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccination Against Pertussis, Tetanus and Diphtheria in Patients Suffering From Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of High Concentration Ganciclovir Eye Drops in the Treatment of Cytomegalovirus Retinitis
Status: RECRUITING
Conditions: Cytomegalovirus Retinitis|Ganciclovir Eye Drops
Interventions: DRUG: 2% Ganciclovir Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib, Fluorouracil, and Leucovorin in Treating Patients With Metastatic or Unresectable Stomach Cancer
Status: TERMINATED
Conditions: Gastric Cancer
Interventions: DRUG: bortezomib|DRUG: fluorouracil|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Three Stage, Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of Oral PTH (1-34) in Healthy Subjects
Status: COMPLETED
Conditions: Drug Safety
Interventions: DRUG: Teriparatide|DRUG: Teriparatide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Redirected HBV-Specific T Cells in Patients With HBV-related HCC (SAFE-T-HBV)
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: mRNA HBV/TCR T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel in Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Neoplasms
Interventions: DRUG: Docetaxel, Cisplatin, 5-fluorouracil (5-FU), radiotherapy|DRUG: Cisplatin, 5-fluorouracil (5-FU), radiotherapy|OTHER: Cisplatin + radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plasma TMAO and Choline Levels in Individuals With Metabolic Syndrome - Comparison Between Eggs and Choline Supplement.
Status: COMPLETED
Conditions: Coronary Artery Disease|Diabetes|Metabolic Syndrome
Interventions: OTHER: Eggs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Diagnostic Value of Molecular Cytological Analysis (CMA) and Shear Wave Elastography ShearWave (SWE) in Patients With a Thyroid Nodule With Indeterminate Cytology: Feasibility Study
Status: COMPLETED
Conditions: Thyroid Node|Indeterminate Cytology|Surgery Indication
Interventions: PROCEDURE: aspiration in thyroid node for Molecular Cytogenetic Analysis.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Briefs With Tapes Versus Pull Ups for Urinary Incontinence in Older People With Mild to Moderate Dementia (CUPID)
Status: RECRUITING
Conditions: Urinary Incontinence
Interventions: DEVICE: Pull Ups|DEVICE: Styled Briefs with tapes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Microvascular Recovery With Ultrasound in Myocardial Infarction (MRUSMI) Post PCI Trial
Status: COMPLETED
Conditions: STEMI|Chest Pain
Interventions: PROCEDURE: percutaneous intervention (PCI)|DRUG: Microbubbles|PROCEDURE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography
Status: RECRUITING
Conditions: Oral Squamous Cell Carcinoma|Oral Potentially Malignant Disorder|Oral Leukoplakia|Proliferative Verrucous Leukoplakia|Oral Lichen Planus|Oral Lichenoid Lesion|Graft-versus-host-disease|Oral Erythroplakia|Actinic Keratoses|Actinic Cheilitis|Oral Cancer|Oral Disease
Interventions: DEVICE: OCT (Optical Coherence Tomography)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of a Synbiotic "Probiotical®/Bactecal® " in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: Probiotical®/Bactecal®|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The INVADE Study: INnominate Vein Approach for Central Catheterization in Difficult to cannulatE Patients
Status: RECRUITING
Conditions: Critical Illness
Interventions: PROCEDURE: Internal jugular vein catheterization|PROCEDURE: Subclavian vein catheterization|PROCEDURE: Innominate vein catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lofexidine and Oral THC on Marijuana Withdrawal and Relapse
Status: COMPLETED
Conditions: Marijuana Dependence
Interventions: DRUG: Lofexidine|DRUG: dronabinol|DRUG: Marijuana
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of [14C] ABBV-CLS-7262 in Healthy Male Volunteers Following Single Oral Dose Administration
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: [14C] ABBV-CLS-7262
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Systemic Targeted Adaptive RadioTherapy of NeuroEndocrine Tumors.
Status: RECRUITING
Conditions: Neuroendocrine Tumors
Interventions: DRUG: 177Lu-DOTATOC|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Focused Ultrasound on Abdominal and Intrahepatic Fat in Patients With Non-alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Fatty Liver
Interventions: PROCEDURE: focused ultrasound, diet and exercise|PROCEDURE: diet and exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EuroPainClinicsStudy IX
Status: COMPLETED
Conditions: Failed Back Surgery Syndrome
Interventions: PROCEDURE: Epiduroscopy treatment|PROCEDURE: Racz catheter epidural procedure|PROCEDURE: Caudal epidural block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Collection of Female Specimens for Testing With Gen-Probe APTIMA (Registered Trademark) Assays
Status: TERMINATED
Conditions: Chlamydia Infections|Gonorrhea|Trichomonas Infections
Interventions: DEVICE: APTIMA® Trichomonas vaginalis & APTIMA® COMBO 2® Assays
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PREDIGA 2: Spanish Acronym of "Educational and Diagnostic Project for Gaucher and ASMD"
Status: RECRUITING
Conditions: Gaucher Disease|Acid SphingoMyelinase Deficiency|ASMD|Niemann-Pick Diseases|Splenomegaly
Interventions: OTHER: Patient with splenomegaly or splenectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of RTP-026 to Assess Safety, Tolerability and Efficacy in Patients With ST-Elevation Myocardial Infarction (STEMI)
Status: RECRUITING
Conditions: ST Elevation Myocardial Infarction
Interventions: DRUG: RTP-026|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Transplantation of Mesenchymal Stem Cells for Treatment of Patients With Onset of Type 1 Diabetes
Status: UNKNOWN
Conditions: Evidence of Liver Transplantation
Interventions: BIOLOGICAL: Autologous transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of BIOdegradable Polymer and DuRablE Polymer Drug-eluting Stents in an All COmeRs PopulaTion (BIO-RESORT)
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Angina Pectoris|Angina, Unstable|Myocardial Infarction|Coronary Artery Disease|Coronary Stenosis|Coronary Restenosis
Interventions: DEVICE: Orsiro|DEVICE: Synergy|DEVICE: Resolute Integrity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Electronic Health Record Strategies to Promote Diverse Participation in Research
Status: COMPLETED
Conditions: Patient Participation
Interventions: OTHER: Traditional Letter|OTHER: Direct to Patient Message|OTHER: Chatbot|OTHER: Banner
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Smoking Tobacco and Drinking Study
Status: COMPLETED
Conditions: Smoking|Heavy Episodic Drinking
Interventions: BEHAVIORAL: Tobacco Status Project Intervention|BEHAVIORAL: Tobacco Status Project + Alcohol Intervention|DRUG: nicotine patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an Aquatic Physical Exercise Program on Glycaemic Control and Perinatal Outcomes of Gestational Diabetes: Study Protocol for a Randomized Controlled Trial
Status: COMPLETED
Conditions: Diabetes, Gestational
Interventions: OTHER: Aquatic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NMDA-enhancing Agent for the Treatment of Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DRUG: DAOIB|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of ISIS GCGRRx on Hepatic Lipid and Glycogen Content in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: ISIS-GCGRRx|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant in Participants With Presumed Nonalcoholic Steatohepatitis (NASH)
Status: TERMINATED
Conditions: Nonalcoholic Steatohepatitis (NASH)
Interventions: DRUG: Miricorilant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT