pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effects of a Jump Rope Exercise Program on Body Composition and Self-efficacy in Obese Adolescent Girls
Status: COMPLETED
Conditions: Prehypertension|Blood Pressure|Abdominal Obesity|Self Efficacy|Adiposity|Insulin Sensitivity
Interventions: OTHER: 12-week jump rope exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Flurbiprofen Axetil for Uterine Contraction Pain
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Saline|DRUG: Flurbiprofen Axetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Travoprost Intraocular Implant in Conjunction With Cataract Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: iDose TR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Efficacy of a Robotic Device for Hand Rehabilitation
Status: COMPLETED
Conditions: Stroke|Upper Extremity Hemiplegia|Disorder of Hand
Interventions: OTHER: General Rehabilitation|DEVICE: Specific hand rehabilitation by Gloreha device|OTHER: Specific hand rehabilitation performed by physiotherapist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Intravenous Interferon Beta-Ia Safety and Preliminary Efficacy in Hospitalized Subjects With COVID-19
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: IFN beta-1a|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pharmacokinetics and Pharmacodynamics of Sugammadex in Reversal of Vecuronium-induced Neuromuscular Blockade
Status: UNKNOWN
Conditions: Pharmacokinetics|Pharmacodynamics
Interventions: DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: University of Iowa Interventional Psychiatry Service Patient Registry
Status: RECRUITING
Conditions: Treatment Resistant Depression|Major Depressive Episode|Major Depression|Major Depressive Disorder|Bipolar Disorder|Bipolar Depression|Obsessive-Compulsive Disorder
Interventions: DEVICE: Electroconvulsive Therapy (ECT)|DEVICE: Transcranial Magnetic Stimulation (TMS)|DRUG: Ketamine|DRUG: Esketamine|DEVICE: Deep Transcranial Magnetic Stimulation (dTMS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Estradiol Valerate Pretreatment in Antagonist Protocol for Poor Ovarian Response Patient
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Follitropin Beta;MSD|DRUG: Ganirelix|DRUG: hCG|DRUG: estradiol valerate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Curcuminoids on Aberrant Crypt Foci in the Human Colon
Status: TERMINATED
Conditions: Aberrant Crypt Foci
Interventions: DRUG: sulindac|DRUG: curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase I Study to Determine the Safety and Immunogenicity of the Candidate Influenza Vaccine ChAdOx1-NP+M1
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: ChAdOx1-NP+M1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effect of COX-2 Selective Inhibitors on Postoperative Insulin Resistance After Gastrointestinal Laparoscopic Surgery
Status: UNKNOWN
Conditions: Gastrointestinal Cancer
Interventions: DRUG: parecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Impact of Preemptive Epidural Analgesia on Acute Postoperative Pain in Pediatric Orthopedic Surgery
Status: COMPLETED
Conditions: Pediatric Surgical Patients|Preemptive Epidural Analgesia
Interventions: PROCEDURE: 0.2 ml/kg of 0.2% ropivacaine|PROCEDURE: 0.2mg/kg of Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Two Interventions for Early Stage Dementia: A Comparative Efficacy Trial
Status: COMPLETED
Conditions: Dementia
Interventions: BEHAVIORAL: ESML-EX (Physical Activity Program)|BEHAVIORAL: ESML-Social (Social Activity Program)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Motor Imagery Exercises and Brain Stimulation TMS Type PAS in Patients After Hemiplegic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: PROCEDURE: Paired Associative Stimulation|PROCEDURE: Paired Associative Stimulation + Motor Imagery exercises|PROCEDURE: Placebo Paired Associative Stimulation + Motor Imagery exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Low Dose Total Skin Electron Beam Radiation Therapy and Mechlorethamine Hydrochloride Gel in Treating Patients With Mycosis Fungoides
Status: WITHDRAWN
Conditions: Mycosis Fungoides
Interventions: DRUG: Mechlorethamine Hydrochloride Gel|PROCEDURE: Total Skin Electron Beam Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: JAGUAR Trial (Outside United States; OUS): ObJective Analysis to GaUge EVAR Outcomes Through Randomization
Status: NOT_YET_RECRUITING
Conditions: AAA|AAA - Abdominal Aortic Aneurysm
Interventions: DEVICE: Alto Abdominal Stent Graft System|DEVICE: FDA Approved EVAR AAA Graft Systems
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Assessment of Lopinavir/Ritonavir and Maraviroc
Status: TERMINATED
Conditions: HIV Infections|Acquired Immunodeficiency Syndrome
Interventions: DRUG: lopinavir/ritonavir plus maraviroc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Adherence to Oral Antipsychotic Medications in People With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Med-eMonitor|BEHAVIORAL: PharmCAT|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of SHR-1209 Combined With Lipid-lowering Agents in Patients With Hypercholesterolemia
Status: COMPLETED
Conditions: Non-familial Hypercholesterolemia|Mixed Hyperlipidemia
Interventions: DRUG: SHR-1209 ;placebo|DRUG: SHR-1209 ;placebo|DRUG: SHR-1209 ;placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DREAM: Does Inhaled Fluticasone REsult in Obstructive Sleep Apnea Manifestations?
Status: COMPLETED
Conditions: Lung Disease
Interventions: DRUG: FP 220 mcg 2 puffs BID
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Navigation Services to Avoid Rehospitalization (NavSTAR)
Status: COMPLETED
Conditions: Opioid-use Disorder|Cocaine Use Disorder|Alcohol Use Disorder
Interventions: BEHAVIORAL: NavSTAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Quality of Recovery (QoR)-15 Scores Between Propofol and Remimazolam Anesthesia
Status: COMPLETED
Conditions: Patients Undergoing Thyroid Surgery for Neoplasm
Interventions: DRUG: Arm I (Propofol group)|DRUG: Arm II (Remimazolam group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of the Effectiveness of Intra-operative Ozurdex® in Vitrectomy Surgery for Epiretinal Membranes
Status: UNKNOWN
Conditions: Epiretinal Membrane|Macular Edema
Interventions: DRUG: Ozurdex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing Influenza and Tdap Vaccination of Pregnant Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Immunization; Infection|Pregnancy Related
Interventions: BEHAVIORAL: VAX-MOM Intervention|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: DPP-4 Inhibition and TZD for DM Prevention
Status: TERMINATED
Conditions: Prediabetic State
Interventions: DRUG: Sitagliptin + Pioglitazone PLACEBO|DRUG: Sitagliptin + Pioglitazone|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: "Nanotechnologies Applied to General Surgery and Emergency Surgery: Buckypaper as a New Fixing Method for Prosthetic Materials for the Treatment of Hernia and Incisional Hernia in Laparotomy and Laparoscopic
Status: UNKNOWN
Conditions: Hernia|Incisional Hernia
Interventions: DEVICE: PPL fixation by BP|DEVICE: PPL mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics (PK) of RV1162 in Healthy Subjects and COPD Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)|Healthy Volunteers
Interventions: DRUG: RV1162 single dose|DRUG: RV1162 matching placebo single dose|DRUG: RV1162: 7 day repeat dose|DRUG: RV1162 matching placebo: 7 day repeat dose|DRUG: RV1162: 14 day repeat dose|DRUG: RV1162 matching placebo: 14 day repeat dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Clesrovimab (MK-1654) in Infants (MK-1654-002)
Status: COMPLETED
Conditions: Respiratory Tract Infection|Respiratory Syncytial Virus
Interventions: DRUG: Clesrovimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Aims to Explore the Safety, Tolerability, and Preliminary Efficacy of SCTB14 in Adult Patients With Advanced Malignant Solid Tumours.
Status: NOT_YET_RECRUITING
Conditions: Advanced Malignant Solid Tumours
Interventions: DRUG: SCTB14
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Fibrate Therapy in Two Patients With Neutral Lipid Storage Disease With Myopathy (NLSDM)
Status: COMPLETED
Conditions: Neutral Lipid Storage Disease
Interventions: DRUG: Fibrate treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxygen Assist Module in Preterm Infants on High Flow Nasal Cannula Support.
Status: UNKNOWN
Conditions: Preterm Birth
Interventions: DEVICE: High Flow Nasal Cannula withAutomatic control of FiO2 using OAM|DEVICE: High Flow Nasal Cannula with manual control of FiO2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study With SAGE-547 for Super-Refractory Status Epilepticus
Status: COMPLETED
Conditions: Super-Refractory Status Epilepticus
Interventions: DRUG: SAGE-547|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen Effects on Persistent Post-concussive Symptoms
Status: ACTIVE_NOT_RECRUITING
Conditions: Persistent Post-concussive Syndrome|Concussion Post Syndrome
Interventions: DRUG: Hyperbaric oxygen at 1.5 ATA|DRUG: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Music & Auditory Beat Stimulation on Anxiety
Status: COMPLETED
Conditions: Anxiety
Interventions: BEHAVIORAL: Music & Auditory Beat Stimulation|BEHAVIORAL: Music Alone|BEHAVIORAL: Auditory Beat Stimulation|BEHAVIORAL: Pink Noise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Capecitabine Plus Oxaliplatin in Combination With Pre-operative Pelvic Radiotherapy in Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Ultra-low-dose Veo Algorithm With the Gold Standard Filtered Back Projection for Detecting Pulmonary Asbestos-related Conditions
Status: COMPLETED
Conditions: Asbestos-exposed Workers
Interventions: DEVICE: New algorithm called VeoTM (General Electric Healthcare, Milwaukee, MI, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pregabalin for the Treatment of Uremic Pruritus
Status: UNKNOWN
Conditions: Uremic Pruritus
Interventions: DRUG: pregabalin 75mg daily for 12 weeks|DRUG: fexofenadine 60 mg daily for 12 weeks|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ALK21-013: Efficacy and Safety of Medisorb® Naltrexone (VIVITROL®) in Adults With Opioid Dependence
Status: COMPLETED
Conditions: Opiate Dependence
Interventions: DRUG: VIVITROL® 380 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lisinopril or Coreg CR® in Reducing Side Effects in Women With Breast Cancer Receiving Trastuzumab
Status: COMPLETED
Conditions: Breast Cancer|Cardiac Toxicity
Interventions: DRUG: Coreg CR®|DRUG: lisinopril|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Absolute Bioavailability Study in Healthy Participants Comparing Oral to Intravenous Administration of GDC-0973 (Cobimetinib)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: GDC-0973 IV Infusion|DRUG: GDC-0973 Oral Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Effects of Different Protein Diet in Hemodialysis Patients
Status: UNKNOWN
Conditions: Diffenence of Protein Diets on Hemodialysis Patients
Interventions: DIETARY_SUPPLEMENT: protein diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective and Retrospective Cohort Study to Find New Prognostic Factors and Therapeutic Targets in Patients With Newly Diagnosed or Relapsed Malignant Hematologic Disorder Excluding Acute Leukemia
Status: UNKNOWN
Conditions: Malignant Hematologic Disorder
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Potato Fiber on Appetite and Fecal Fat Excretion
Status: COMPLETED
Conditions: Fecal Fat Increased|Obesity|Appetite
Interventions: DIETARY_SUPPLEMENT: FiberBind|DIETARY_SUPPLEMENT: RG-I fiber|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Clinical Observation of Warm Needling Combined With and Electroacupuncture Therapy on Ovulatory Dysfunction
Status: COMPLETED
Conditions: Warm Needling|Electroacupuncture|Ovulation Dysfunction
Interventions: OTHER: warm needling combined with electroacupuncture|DRUG: The treatment with letrozole tablets was started on the fifth day of the menstrual cycle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TU 025 Keishi Bukuryo Gan for Post-menopausal Hot Flash Management
Status: COMPLETED
Conditions: Hot Flashes|Menopause
Interventions: DRUG: TU 025 Keishi Bukuryo Gan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Administration During Flexible Bronchoscopy and Endobronchial Ultrasound
Status: TERMINATED
Conditions: Bronchiectasis Adult|Mediastinal Lymphadenopathy|Pneumonia|Chest--Diseases|Infiltrates|Bronchopulmonary Disease|Cancer, Lung
Interventions: DRUG: Topical lidocaine|DRUG: Nebuliser solution|DRUG: Nebuliser Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasonographic Evaluation of the Effectiveness of Different Techniques
Status: ENROLLING_BY_INVITATION
Conditions: Ultrasound Evaluation of the Effect of Manual Lymph Drainage|Effect of Manual Lymph Drainage on Carpal Tunnel Syndrome
Interventions: OTHER: Manual lymphatic drainage|DEVICE: splint|OTHER: Nerve gliding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Utility of the Administration of Chesnut and Quebracho Extract for Irritable Bowel Syndrome Diarrhea Predominant
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Diarrhea
Interventions: DIETARY_SUPPLEMENT: ARBOX (QUEBRACHO AND CHESNUT EXTRACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Denileukine Diftitox for Relapsed ALCL
Status: WITHDRAWN
Conditions: Anaplastic Large-Cell Lymphoma
Interventions: DRUG: Denileukin Diftitox|DRUG: Denileukin diftitox, ifosfamide, cyclophosphamide, etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Artificial Pancreas Technology to Reduce Glycemic Variability and Improve Cardiovascular Health in Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes
Interventions: DEVICE: Tandem t:slim X2 with Control-IQ Technology|DEVICE: Sensor augmented pump (SAP) therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fludarabine and Cyclophosphamide With or Without Rituximab in Patients With Previously Untreated Chronic B-Cell Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Fludarabine Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irinotecan and Docetaxel in Treating Patients With Refractory Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: docetaxel|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy, Safety and Tolerability of ACZ885 (Canakinumab) in Pediatric and Young Adult Patients With Sickle Cell Anemia
Status: COMPLETED
Conditions: Sickle Cell Anemia
Interventions: DRUG: ACZ885|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety Extension Study to Evaluate the Long-term Safety of QGE031 in Chronic Spontaneous Urticaria (CSU) Patients
Status: COMPLETED
Conditions: Chronic Spontaneous Urticaria
Interventions: BIOLOGICAL: Ligelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Beta-adrenoceptor Inverse Agonist, Nadolol, in Mild Asthma
Status: UNKNOWN
Conditions: Mild Persistent Asthma, Uncomplicated
Interventions: DRUG: Nadolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Can Intermittent Fasting Mimic the Metabolic and Cardiovascular and Anti-aging Effects of Calorie Restriction?
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: OTHER: Intermittent Fasting group|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of WVT078 in Patients With Multiple Myeloma (MM)
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma (MM)
Interventions: BIOLOGICAL: WVT078|DRUG: WHG626
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Supervised Ground Walk Training and Treadmill Walk Training in COPD Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: BEHAVIORAL: Ground walk training|BEHAVIORAL: Supervised Treadmill Walk training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Lidocaine and Postoperative Outcomes After Cardiac Surgery
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: DRUG: Lidocaine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Physiologic Volume and Atrophy of Brain and Spinal Cord Measured by Magnetic Resonance Imaging
Status: UNKNOWN
Conditions: Cognitive Change|Atrophy Brain|Atrophy; Spinal Cord|Multiple Sclerosis
Interventions: OTHER: Magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Metabolic Changes in Healthy Subjects With Acute Binge Drink
Status: ACTIVE_NOT_RECRUITING
Conditions: Binge Drinking|Liver Injury|Hepatic Steatosis
Interventions: OTHER: vodka|OTHER: water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Does Ultrasound Assessment for Extravascular Lung Water and IVC Measurement Affect Outcomes in Inpatient Heart Failure Management?
Status: UNKNOWN
Conditions: Acute Decompensated Heart Failure
Interventions: DIAGNOSTIC_TEST: Daily pocus exam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Plus Booster Shots in Men With Prostate Cancer Undergoing Treatment With Radical Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer|Prostatic Neoplasms|Neoplasms, Prostate
Interventions: BIOLOGICAL: PROSTVAC-V/TRICOM|BIOLOGICAL: PROSTVAC-F/TRICOM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance Evaluation of LumiraDx COVID-19 (SARS-CoV-2) Ag ULTRA Test (ASPIRE-2)
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: DIAGNOSTIC_TEST: Nasal Swab|DIAGNOSTIC_TEST: Nasopharyngeal swab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: WASH For Everyone: Testing Alternative Approaches to Sanitation and Hygiene Behaviour Change in Chiradzulu, Malawi
Status: RECRUITING
Conditions: Behavior
Interventions: OTHER: Community-Led Total Sanitation|OTHER: Care Groups
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: INPWT on Wound Complications & Clinical Outcomes After Lower Extremity Sarcoma Surgery Preop Radiation Therapy Patients
Status: RECRUITING
Conditions: Soft-tissue Sarcoma|Wound Complication
Interventions: OTHER: Incisional Negative Pressure Wound Therapy (INPWT)|OTHER: Wound Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Low Dose Corticosteroids on Perioperative Markers of Thrombosis and Fibrinolysis in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: DRUG: Hydrocortisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety and Tolerability of Fixed Doses of Intranasal Esketamine in Japanese Participants With Treatment Resistant Depression
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Placebo|DRUG: Intranasal esketamine (28 mg)|DRUG: Intranasal esketamine (56 mg)|DRUG: Intranasal esketamine (84 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety, Tolerability, and Efficacy of IVT Pre-op 0.3mg Pegaptanib Sodium Versus Sham, for Management of Tractional Retinal Detachment and Vitreous Hemorrhage With Proliferative Diabetic Retinopathy
Status: WITHDRAWN
Conditions: Proliferative Diabetic Retinopathy
Interventions: DRUG: Macugen|DRUG: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomized, Double-Blind, Placebo-Controlled Trial Comparing VitroGro® ECM to Placebo in Patients With Venous Leg Ulcers
Status: WITHDRAWN
Conditions: Venous Leg Ulcer
Interventions: DRUG: VitroGro® ECM|DRUG: Dulbecco's Phosphate Buffered Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRISTINE - Personalised Approach to Improve aSThma prescrIbing iN childrEn
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: Montelukast or Salmeterol or Theophylline or Steroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 and the Healthy Minds Program for Educators
Status: COMPLETED
Conditions: Anxiety|Depression|Psychological Stress|Psychological Distress|Well-being
Interventions: BEHAVIORAL: Healthy Minds Program Foundations Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HealthCall-S: A Pilot Study Targeting Concurrent Non-injection Drug Use and Alcohol in HIV Primary Care Clinics
Status: COMPLETED
Conditions: Alcohol or Other Drugs Use
Interventions: BEHAVIORAL: HealthCall+Motivational Interviewing|BEHAVIORAL: Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug Utilisation Post-authorisation Study of New Users of Aclidinium Bromide (Monotherapy or in Combination)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Aclidinium bromide|DRUG: Aclidinium bromide/formoterol|DRUG: Other COPD medication
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vaccinating Children After Chemotherapy
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: Prevnar®13|BIOLOGICAL: Pneumovax® 23|BIOLOGICAL: Pediacel®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Single and Multiple Ascending Oral Dose Study of RX-10001 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: RX-10001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurofeedback Training of Metacognition in Subjects With Alcohol Use Disorder. Disorder Induces Neural Modifications: an Event-related Potentials Study
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DEVICE: Neurofeedback active|DEVICE: Neurofeedback placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bortezomib, Vorinostat and Dexamethasone for Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL)
Status: TERMINATED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Bortezomib|DRUG: Vorinostat|DRUG: Dexamethasone|DRUG: Methotrexate|DRUG: Imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Galunisertib in Participants With Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Galunisertib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Population Immunity AgaiNst mosquitO-borne Diseases in Vanuatu
Status: COMPLETED
Conditions: Arbovirus Disease|Zika|Dengue|Ross River|Chikungunya|COVID-19
Interventions: OTHER: Blood collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Alar Batten Graft vs Latera for Nasal Valve Collapse
Status: WITHDRAWN
Conditions: Nasal Valve Incompetence
Interventions: DEVICE: Latera Device|PROCEDURE: Alar Batten Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: HAL-MPE1 First-in-human
Status: COMPLETED
Conditions: Peanut Allergy
Interventions: DRUG: HAL-MPE1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuraxial Labor Analgesia and the Incidence of Postpartum Depression
Status: COMPLETED
Conditions: Parturition|Analgesia, Obstetrical|Depression, Postpartum
Interventions: PROCEDURE: No neuraxial labor analgesia|PROCEDURE: Neuraxial labor analgesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Goal Oriented Strategy to Preserve Ejection Fraction Trial
Status: UNKNOWN
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apatinib Combined With Temozolomide and Etoposide Capsules in the Treatment of Recurrent Medulloblastoma in Children
Status: RECRUITING
Conditions: Recurrent Medulloblastoma
Interventions: DRUG: Apatinib Combined With Temozolomide and Etoposide Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of MTC896 Gel in Subjects With Acne
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: 0.75% (w/w) MTC896 Gel Once Daily|DRUG: 0.75% (w/w) MTC896 Gel Twice Daily|DRUG: 1.5% (w/w) MTC896 Gel Once Daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Feasibility Study on Ultrafiltration and Blood Volume Measurements
Status: TERMINATED
Conditions: Acute Decompensated Heart Failure|Fluid Overload
Interventions: DEVICE: Aquadex FlexFlow System and BVA-100
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: S1 Plus Anlotinib in Treating Patients With Refractory or Relapsed Small-cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Cancer Recurrent
Interventions: DRUG: S1/Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a 36-week Tablet-based Intervention on Multiple Domains in Older Adults With Mild Cognitive Impairment
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: OTHER: Kodro+|OTHER: Kodro+D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TuLip : Role of the Tumor Environment in Cancer-related Fat Loss
Status: TERMINATED
Conditions: Cancer|Cachexia|Adipose Tissue
Interventions: PROCEDURE: Nissen Fundoplication, cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Efficacy and Serum Proteomic Profiling of Suan-Zao-Ren Tang for Sleep Disturbance During Methadone Maintenance
Status: COMPLETED
Conditions: Opiate Dependence
Interventions: DRUG: Suan-Zao-Ren Tang|DRUG: Suan-Zao-Ren Tang placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MELT-300 (Midazolam and Ketamine Sublingual Tablets) for Sedation and Intraoperative Ocular Analgesia in Participants Undergoing Cataract Extraction With Lens Replacement (CELR)
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: MELT-300|DRUG: Midazolam alone|DRUG: Ketamine alone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Paracetamol, Chlorpheniramine and Phenylephrine in the Treatment of Common Cold and Flu Syndrome
Status: COMPLETED
Conditions: Flu
Interventions: DRUG: Active|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PhII Study STA-9090 as Second or Third-Line Therapy for Metastatic Pancreas Cancer
Status: TERMINATED
Conditions: Adenocarcinoma of the Pancreas|Recurrent Pancreatic Cancer|Stage IV Pancreatic Cancer
Interventions: DRUG: STA-9090|RADIATION: Radiologic imaging|PROCEDURE: blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmaco Mechanical Thrombolysis Associated With Anticoagulation Compared With Anticoagulation in the Acute Phase of Very Symptomatic Proximal Venous Thrombosis of the Lower Limbs.
Status: NOT_YET_RECRUITING
Conditions: Iliofemoral Venous Thrombosis
Interventions: DEVICE: pharmaco mechanical thrombolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma Injection for Knee Pain
Status: COMPLETED
Conditions: Degenerative Chondropathy|Early Osteoarthritis
Interventions: BIOLOGICAL: Platelet-rich Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Cingal® and Triamcinolone Hexacetonide for the Relief of Knee Osteoarthritis Pain
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Cingal|DRUG: Triamcinolone Hexacetonide (TH)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fludarabine and Thalidomide in Treating Patients With Newly Diagnosed Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: fludarabine phosphate|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effects of Adapted Tango and Multidimensional Intervention in pREvention of Dementia in agiNG (STRENGTH)
Status: ACTIVE_NOT_RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Adapted Tango Dancing|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating CMP-001 in Combination With Atezolizumab in Participants With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: CMP-001|DRUG: Atezolizumab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Integrating the Outcomes4Me Smartphone Navigation Application Into the Care Management of Breast Cancer Patients
Status: UNKNOWN
Conditions: Breast Cancer|Invasive Breast Cancer|Metastatic Breast Cancer|Breast Carcinoma|Metastatic Breast Carcinoma
Interventions: DEVICE: Outcomes4Me Mobile App
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Enhanced Recovery After Surgery (ERAS) Pathway With Conventional Pathway After Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: OTHER: ERAS pathway|OTHER: Standard pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Pregabalin on the Duration of the Spinal Anesthesia and the Early Postoperative Pain After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Pregabalin 150mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety and Efficacy of Atralin (Tretinoin 0.05%) Gel for the Treatment of Rosacea
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: tretinoin gel 0.05%|DRUG: vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Value of Prick Therapy Combined With Wheat Grain Moxibustion in the Treatment of Spleen Deficiency and Dampness Obstructed Cancer
Status: RECRUITING
Conditions: Pricking Therapy on the Back Shu Points|Wheat Grain Moxibustion on the Back Shu Points
Interventions: OTHER: pricking therapy and wheat grain moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Directed High-dose Nasal Steroids on Residual Smell Loss in Sinus Patients After Sinus Surgery
Status: WITHDRAWN
Conditions: Olfaction Disorders|Sinusitis|Paranasal Sinus Diseases
Interventions: DRUG: Budesonide Respules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Effects of Dao-In Exercise on the Perimenopausal Women With Sleep Disturbance
Status: UNKNOWN
Conditions: Peri-menopausal Women|Sleep Disturbances|Dao-in Exercise|Body Constitution
Interventions: BEHAVIORAL: Duo-in exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Monitoring and Evaluation of a Cognitive Behavioral Therapy Program Focused on Attention and Emotion Regulation for Children With Fetal Alcohol Spectrum Disorder
Status: WITHDRAWN
Conditions: Fetal Alcohol Spectrum Disorders|Hyperactivity Disorder|Attention Deficit
Interventions: OTHER: cognitivo-comportmental therapy|OTHER: body mediation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ELECTROMAGNETIC FIELD ON NECK PAIN AND PROPRIOCEPTION IN CERVICAL RADICULOPATHY
Status: UNKNOWN
Conditions: Cervical Radiculopathy
Interventions: OTHER: selected exercise program|DEVICE: Electromagenetic Field therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intrathecal Naloxone in the Incidence of Pruritis After C.S
Status: COMPLETED
Conditions: Pruritis
Interventions: DRUG: Fentanyl|DRUG: Naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chemotherapy Followed By Vaccine Therapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: Autologous dendritic cell-adenovirus p53 vaccine|DRUG: Carboplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbetocin Versus Oxytocin in the Prevention of Post Partum Haemorrhage (PPH) in Women Undergoing Caesarean Sections for Placenta Previa: A Randomised Controlled Trial
Status: UNKNOWN
Conditions: Post Partum Haemorrhage
Interventions: DRUG: Carbetocin|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Telcagepant (MK-0974) Treatment of Migraine in Participants With Stable Vascular Disease (MK-0974-034)
Status: COMPLETED
Conditions: Migraine Disorders|Heart Disease|Cerebrovascular Accident|TIA (Transient Ischemic Attack)|Vascular Diseases|Peripheral Vascular Diseases
Interventions: DRUG: Telcagepant|DRUG: Acetaminophen/Paracetamol|DRUG: Placebo to Telcagepant|DRUG: Placebo to Acetaminophen/Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of GLPG0634 in Subjects With Active Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: GLPG0634|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chiauranib in Combination With Chemotherapy in Patients With Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: chiauranib|DRUG: etoposide|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to Two Different HIV Vaccines, Each Followed by a Adenoviral Vaccine Boost, in HIV Uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: VRC-HIVADV014-00-VP|BIOLOGICAL: VRC-HIVDNA009-00-VP|BIOLOGICAL: FFB|BIOLOGICAL: PBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Studying Biomarkers in Samples From Patients With Recurrent or Metastatic Head and Neck Cancer Treated on E1302 Trial
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: GENETIC: mutation analysis|GENETIC: polymerase chain reaction|GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of a Combined Transcranial Direct Current Stimulation and Virtual Reality Intervention
Status: COMPLETED
Conditions: Stroke|Hemiparesis|Chronic Stroke|Upper Limb Injury
Interventions: DEVICE: REACt system|OTHER: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Endoscopic Ultrasound vs Surgical Gastrojejunostomy for Management of GOO.
Status: RECRUITING
Conditions: Malignant Gastric Outlet Obstruction
Interventions: PROCEDURE: Surgical gastrojejunostomy (S-GJ)|PROCEDURE: EUS-guided gastrojejunostomy (EUS-GJ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Recombinant Von Willebrand Factor (rVWF) With or Without ADVATE in Children With Severe Von Willebrand Disease (VWD)
Status: RECRUITING
Conditions: Von Willebrand Disease
Interventions: BIOLOGICAL: von Willebrand factor (Recombinant)|BIOLOGICAL: Antihemophilic Factor (Recombinant)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT