pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Validation of Subjective Rating Scales Used to Assess Surgical Conditions in Abdominal Surgery
Status: COMPLETED
Conditions: Surgical Conditions|Rating Scales|Laparoscopy|Neuromuscular Blockade|Pneumoperitoneum
Interventions: DRUG: Rocuronium|DRUG: sugammadex|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Investigate the Renal Movement by Single Lung Ventilation in Patients Administered RIRS for Kidney Stones.
Status: UNKNOWN
Conditions: Perioperative/Postoperative Complications|Kidney Stone
Interventions: DIAGNOSTIC_TEST: Preoperative Parameters|OTHER: Peroperative Parameters|OTHER: Postoperative Parameters|OTHER: Movement of kidney|PROCEDURE: single lung ventilation|PROCEDURE: standard ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of V419 Given Concomitantly With Prevnar 13™ and RotaTeq™ (V419-006)
Status: COMPLETED
Conditions: Bacterial Infections|Virus Diseases
Interventions: BIOLOGICAL: V419|BIOLOGICAL: PENTACEL™|BIOLOGICAL: Prevnar 13™|BIOLOGICAL: RotaTeq™|BIOLOGICAL: Recombivax HB vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Investigate Efficacy of YAZ in the Treatment of Dysmenorrhea
Status: WITHDRAWN
Conditions: Dysmenorrhea
Interventions: DRUG: EE20/DRSP(YAZ,BAY86-5300)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Variant Immunologic Landscape Trial (COVAIL Trial)
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: AS03|BIOLOGICAL: BNT162b2|BIOLOGICAL: BNT162b2 (B.1.1.529)|BIOLOGICAL: BNT162b2 (B.1.351)|BIOLOGICAL: BNT162b2 bivalent (wildtype and Omicron BA.1)|BIOLOGICAL: BNT162b2 bivalent (wildtype and Omicron BA.4/BA.5)|BIOLOGICAL: CoV2 preS dTM [B.1.351]|BIOLOGICAL: CoV2 preS dTM/D614|BIOLOGICAL: CoV2 preS dTM/D614+B.1.351|BIOLOGICAL: mRNA-1273|BIOLOGICAL: mRNA-1273.351|BIOLOGICAL: mRNA-1273.529|BIOLOGICAL: mRNA-1273.617.2|OTHER: Sodium Chloride, 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Remission Induction Chemotherapy Prior to Allogeneic SCT in Relapsed and Poor-response Patients With AML
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: HAM|DRUG: LDAC and/or Mitoxantrone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of the Effect of Low Level Laser Light Therapy on Reducing Upper Arm Circumference
Status: COMPLETED
Conditions: Body Contouring
Interventions: DEVICE: Erchonia(r) ML Scanner (MLS)|DEVICE: inactive placebo laser device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Prehabilitation During Chemotherapy in Patients With Colorectal Liver Metastases
Status: RECRUITING
Conditions: Prehabilitation|Neoadjuvant Therapy|Liver Metastases
Interventions: BEHAVIORAL: Physical Prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combined Non-invasive Coronary Angiography and Myocardial Perfusion Imaging Using 320 Detector Computed Tomography
Status: COMPLETED
Conditions: Arterial Occlusive Diseases|Coronary Disease|Heart Diseases|Myocardial Ischemia|Vascular Diseases|Arteriosclerosis|Ischemia|Coronary Artery Disease
Interventions: PROCEDURE: 320 Volume Detector Computed Tomography|OTHER: Other: Multidetector Computed Tomography - 320 detectors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Research Study to See How Semaglutide Helps People With Excess Weight and Type 2 Diabetes Lose Weight
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Diabetes Mellitus, Type 2
Interventions: DRUG: Semaglutide|DRUG: Semaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reconstruction Implant Bone After Removal Using Porous Titanium Prosthesis
Status: COMPLETED
Conditions: Otorhinolaryngologic Diseases
Interventions: DEVICE: Mandibular prosthesis made of a new highly biointegratable material
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Aztreonam for Inhalation Solution vs Tobramycin Inhalation Solution in Patients With Cystic Fibrosis & Pseudomonas Aeruginosa
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Aztreonam for Inhalation Solution (AZLI)|DRUG: Tobramycin Inhalation Solution (TIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of an Acidic Beverage on the Imatinib Exposure After Major Gastrectomy
Status: TERMINATED
Conditions: Gastrointestinal Stromal Tumor|Major Gastrectomy
Interventions: DIETARY_SUPPLEMENT: cola
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Endobronchial Ultrasound Guided Transbronchial Lung Biopsy With or Without Guide Sheath in Lung Tumors and the Analysis of Echoic Patterns of Lung Tumors and Mediastinal Lymph Nodes, and the Association Between Diagnostic Yield of Transbronchial Lung Biopsy and EBUS Echoic Features.
Status: UNKNOWN
Conditions: Lung Neoplasms
Interventions: PROCEDURE: endobronchial ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of NMD670 in Adult Patients With Type 1 and Type 2 Charcot-Marie-Tooth Disease
Status: NOT_YET_RECRUITING
Conditions: Charcot-Marie-Tooth Disease
Interventions: DRUG: NMD670|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of INI-822 in Healthy Volunteers and Participants With Non-alcoholic Steatohepatitis (NASH) or Presumed NASH
Status: RECRUITING
Conditions: Non-alcoholic Steatohepatitis
Interventions: DRUG: INI-822 (A)|OTHER: Placebo (B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of a Cohort of Cases of Synovial Sarcoma Treated in the Orthopedic Surgery and Traumatology Department of the Hospital de Sant Pau Between 1983 and 2016
Status: COMPLETED
Conditions: Soft Tissue Sarcoma Adult
Interventions: OTHER: Soft tissue sarcomas in adults
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Better Everyday Life Among Persons With Chronic Conditions
Status: COMPLETED
Conditions: Chronic Conditions, Multiple
Interventions: OTHER: ABLE|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Talactoferrin in Treating Patients With Relapsed or Refractory Non-Small Cell Lung Cancer or Squamous Cell Head and Neck Cancer
Status: TERMINATED
Conditions: Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma|Recurrent Metastatic Squamous Neck Cancer With Occult Primary|Recurrent Salivary Gland Cancer|Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Nasopharynx|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Recurrent Verrucous Carcinoma of the Larynx|Recurrent Verrucous Carcinoma of the Oral Cavity|Salivary Gland Squamous Cell Carcinoma|Stage III Salivary Gland Cancer|Stage III Squamous Cell Carcinoma of the Hypopharynx|Stage III Squamous Cell Carcinoma of the Larynx|Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage III Squamous Cell Carcinoma of the Nasopharynx|Stage III Squamous Cell Carcinoma of the Oropharynx|Stage III Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage III Verrucous Carcinoma of the Larynx|Stage III Verrucous Carcinoma of the Oral Cavity|Stage IV Non-small Cell Lung Cancer|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IVA Salivary Gland Cancer|Stage IVA Squamous Cell Carcinoma of the Larynx|Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVA Squamous Cell Carcinoma of the Oropharynx|Stage IVA Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVA Verrucous Carcinoma of the Larynx|Stage IVA Verrucous Carcinoma of the Oral Cavity|Stage IVB Salivary Gland Cancer|Stage IVB Squamous Cell Carcinoma of the Larynx|Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Oropharynx|Stage IVB Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVB Verrucous Carcinoma of the Larynx|Stage IVB Verrucous Carcinoma of the Oral Cavity|Stage IVC Salivary Gland Cancer|Stage IVC Squamous Cell Carcinoma of the Larynx|Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVC Squamous Cell Carcinoma of the Oropharynx|Stage IVC Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVC Verrucous Carcinoma of the Larynx|Stage IVC Verrucous Carcinoma of the Oral Cavity|Tongue Cancer
Interventions: BIOLOGICAL: talactoferrin|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Methamphetamine-Dependent and Healthy Volunteers Using a Web-Enabled Cognitive Neuropsychological Evaluation System
Status: UNKNOWN
Conditions: Methamphetamine Dependence
Interventions: DEVICE: Web-Enabled Cognitive Neuropsychological Evaluation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetics and Safety of Alisporivir in Subjects With End Stage Renal Disease on Hemodialysis Compared to Healthy Subjects
Status: COMPLETED
Conditions: Kidney Failure, Chronic
Interventions: DRUG: Alisporivir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: The Effect of Low Level Laser Therapy (LLLT) in Myofacial Pain Syndrome
Status: UNKNOWN
Conditions: Myofacial Pain Syndrome
Interventions: RADIATION: Low level laser therapy|RADIATION: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reconstruction Outcomes in Immediate Post-mastectomy Breast Reconstruction With ADM
Status: UNKNOWN
Conditions: Breast Reconstruction
Interventions: BIOLOGICAL: FlexHD ADM (Cohort A)|BIOLOGICAL: AlloDerm RTU ADM (Cohort B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A RCT of an AEBT Website for Adults With Skin Picking
Status: ACTIVE_NOT_RECRUITING
Conditions: Excoriation (Skin-Picking) Disorder
Interventions: BEHAVIORAL: Acceptance-Enhanced Behavior Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobilizing Early Management of Mental Health Complications After Mild Traumatic Brain Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Mild Traumatic Brain Injury
Interventions: OTHER: Guideline implementation tool|OTHER: Generic information about concussion management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Point of Care Test of LTA Level in Tear Fluid, Measured With a POCT Test, in DE Patients Following IPL Treatment
Status: NOT_YET_RECRUITING
Conditions: Dry Eye
Interventions: DEVICE: M22|DEVICE: sham M22
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Phenytoin on the Ganglion Cell Layer in Patients With Optic Neuritis
Status: COMPLETED
Conditions: Optic Neuritis
Interventions: DRUG: Phenytoin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: KeyLargo: Pembrolizumab + Oxaliplatin + Capecitabine in Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer|Esophagus Cancer
Interventions: DRUG: Oxaliplatin+Capecitabine+Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of GRT6005 in Painful Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Matching Placebo|DRUG: GRT6005|DRUG: GRT6005|DRUG: GRT6005
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photoacoustic Endoscopy in Endometrial Cancer
Status: WITHDRAWN
Conditions: Endometrial Cancer|Benign Neoplasm of Body of Uterus
Interventions: DEVICE: Photoacoustic endoprobe|PROCEDURE: Photoacoustic endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction
Status: RECRUITING
Conditions: Lung Transplant Rejection
Interventions: DRUG: Belumosudil|DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Angiography for Evaluation of the Feeder Vessel in EUS-guided Coils and Cyanoacrylate Therapy for Gastric Varices
Status: COMPLETED
Conditions: Gastric Varices
Interventions: PROCEDURE: angiography in EUS-injection of coils + CYA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhanced Monitoring for Better Recovery and Cancer Experience in Greater Manchester
Status: RECRUITING
Conditions: Colorectal Cancer|Lung Cancer|Hematological Cancer|CAR T-Cell Therapy
Interventions: DEVICE: OURA Ring|DEVICE: WithingsScan Watch|DRUG: Isansys Patient Status Engine|OTHER: Quality of Life Surveys|DIAGNOSTIC_TEST: Blood Samples|OTHER: Daily Weights
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Oral Tyramine Pressor Response Study of CX157 Tablets in Healthy Male Volunteers
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: CX157|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrent Ipilimumab and Stereotactic Ablative Radiation Therapy (SART) for Oligometastatic But Unresectable Melanoma
Status: UNKNOWN
Conditions: Melanoma
Interventions: DRUG: Ipilimumab|RADIATION: Stereotactic Ablative Radiosurgery (SART)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Live Combined Bifidobacterium,Lactobacillus and Enterococcus Capsules on Oral Mucositis in Nasopharyngeal Carcinoma Patients Receiving Radiotherapy.
Status: UNKNOWN
Conditions: Oral Mucositis|Quality of Life
Interventions: OTHER: Lactobacillus, Bifidobacterium and Enterococcus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Biomarkers of Conversion Risk and Treatment Response in Early-Stage Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia Spectrum and Other Psychotic Disorders
Interventions: DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fentanyl Versus Tramadol as Co-administrator to Bupivacaine
Status: COMPLETED
Conditions: Acquired Deformity of Elbow|Forearm|Hand|Wrist
Interventions: PROCEDURE: ultrasound-guided supraclavicular brachial plexus blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Lyophilized or Frozen Bone Allografts for Sinus-lifting
Status: UNKNOWN
Conditions: Disorder of Maxillary Sinus|Accessory; Bone|Bone Atrophy
Interventions: PROCEDURE: freeze bone allograft|PROCEDURE: lyophilized bone allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Staccato Loxapine Thorough QT/QTc Study
Status: COMPLETED
Conditions: Thorough QT/QTc Study
Interventions: DRUG: Inhaled loxapine|DRUG: Inhaled placebo|DRUG: Oral moxifloxacin|DRUG: Oral placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acupressure on Procedural Pain, Anxiety and Hemodynamic Variables During Chest Tube Removal
Status: RECRUITING
Conditions: Pain, Postoperative|Anxiety|Hemodynamic Instability
Interventions: OTHER: Acupressure|OTHER: Placebo acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intra-patient Study With Polymer Free Drug Eluting Stent Versus Abluminal Biodegradable Polymer Drug Eluting Stent With Early OCT (Optical Coherence Tomography) Follow up
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Coroflex® ISAR Drug-eluting stent|DEVICE: Ultimaster® Drug-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Response to Fat and Glucose
Status: COMPLETED
Conditions: Obesity|Insulin Resistance|Healthy
Interventions: OTHER: Glucose tolerance test|OTHER: Fat tolerance test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: First Clinical Study of Erbium - Yttrium Aluminium Garnet (YAG) Laser Vaporization of Cutaneous Neurofibromas
Status: UNKNOWN
Conditions: Cutaneous Neurofibromas
Interventions: PROCEDURE: Erbium-YAG laser vaporization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Facilitating Needle Alignment With Aiming Method
Status: COMPLETED
Conditions: Central Venous Catheters
Interventions: PROCEDURE: subclavian vein catheterization|PROCEDURE: landmark techniques|PROCEDURE: Ultrasound-guided plus needle guide techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: the Accuracy and Safety of Coronary Artery Contrast-enhanced Magnetic Resonance Imaging With Polysaccharide Superparamagnetic Iron Oxide Nanoparticle
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DRUG: domestic polysaccharide superparamagnetic iron oxide nanoparticle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Lebrikizumab (LY3650150) in Combination With Topical Corticosteroid in Moderate-to-Severe Atopic Dermatitis.
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: Lebrikizumab|OTHER: Placebo|OTHER: Topical Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Hazardous Alcohol Use & Human Immunodeficiency Virus (HIV) Viral Load
Status: COMPLETED
Conditions: Alcohol Drinking|HIV
Interventions: BEHAVIORAL: Brief Intervention|BEHAVIORAL: Motivational Enhancement Therapy (MET) Intervention|BEHAVIORAL: Cognitive Behavioral Therapy (CBT) Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test How Well Different Doses of BI 3731579 Are Tolerated
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: BI 3731579|DRUG: Matching placebo to BI 3731579
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cholecalciferol (Vitamin D3) Therapy in Chronic Kidney Disease (CKD) Subjects
Status: COMPLETED
Conditions: Chronic Kidney Disease|Vitamin D Deficiency
Interventions: DRUG: Cholecalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HPV Self-Test Intervention in Ohio Appalachia
Status: COMPLETED
Conditions: Cervical Carcinoma|Human Papillomavirus Infection
Interventions: PROCEDURE: Disease Screening|OTHER: Educational Intervention|OTHER: Informational Intervention|OTHER: Laboratory Biomarker Analysis|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Narcotrend Versus Bispectral Index Monitoring During Sufentanil-Midazolam Anesthesia for Bronchoscopy
Status: COMPLETED
Conditions: Bronchoscopy
Interventions: DEVICE: Narotrend|DEVICE: BIS|DRUG: Sufentanil|DRUG: Lidocaine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: The Efficacy of an Artificial Intelligence Platform to Adapt Visual Aids for Patients With Low Vision: a Randomised Controlled Trial
Status: UNKNOWN
Conditions: Ophthalmology|Low Vision Aids|Artificial Intelligence
Interventions: OTHER: Low vision aids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of omega3 on Congestive Heart Failure
Status: COMPLETED
Conditions: Heart Failure Congestive
Interventions: DIETARY_SUPPLEMENT: placebo|DIETARY_SUPPLEMENT: omga3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FreeStyle Libre Plus Bluetooth Transmitter Adjunct: Can This Improve Glucose Accuracy and Reduce Burden of Hypoglycaemia
Status: WITHDRAWN
Conditions: Type1 Diabetes Mellitus
Interventions: COMBINATION_PRODUCT: FreeStyle Libre with MiaoMiao|DEVICE: FreeStyle Libre alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Pre-injection of Lidocaine on Myoclonus Induced by Induction With Etomidate in Elderly Patients During General Anesthesia
Status: UNKNOWN
Conditions: General Anesthesia
Interventions: DRUG: Lidocaine Hydrochloride Injection|DRUG: Etomidate Fat Emulsion Injection|DRUG: normal saline|DRUG: Midazolam Injection|DRUG: Fentanyl Citrate Injection|DRUG: Rocuronium Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunosuppressive Preparation Followed by Blood Cell Transplant for the Treatment of Blood Cancers in Older Adults
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Graft vs Host Disease|Leukemia|Myelodysplastic Syndrome|Myeloid Leukemia
Interventions: PROCEDURE: Blood cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-Line Chemotherapy and Panitumumab in Advanced Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Carboplatin|DRUG: Vinorelbine|DRUG: panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IS-001 Injection Phase-1 Safety, Tolerance and Pharmacokinetics
Status: COMPLETED
Conditions: Hysterectomy|Surgery
Interventions: DRUG: IS-001|DEVICE: da Vinci® Si/Xi Surgical System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Recombinant Human Platelet-derived Growth Factor in Combination With Collagen Matrix
Status: COMPLETED
Conditions: Gingival Recession|Platelet Derived Growth Factor
Interventions: PROCEDURE: Root coverage procedures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness, Exercise and Nutrition To Optimize Resilience for Individuals With a Spinal Cord Injury.
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: BEHAVIORAL: MENTOR + Telehealth|BEHAVIORAL: Telehealth Only
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Coenzyme Q10 as a Symptomatic Treatment in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Coenzyme Q10 Nanodispersion (Nanoquinone)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Axillary Sentinel Lymph Node Biopsy Versus no Axillary Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: no axillary surgery versus SLNB|PROCEDURE: SLNB versus completion ALND
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effects of Prolonged Standing Compared to Prolonged Sitting on Postprandial Lipemia
Status: COMPLETED
Conditions: Metabolic Syndrome|Atherosclerosis
Interventions: BEHAVIORAL: Prolonged Standing|BEHAVIORAL: Prolonged Sitting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Recognition and Expression of Emotions Program Applied to Schizophrenia Patients
Status: COMPLETED
Conditions: Schizophrenia|Alexithymia|Emotion, Expressed
Interventions: BEHAVIORAL: Emotions Recognition and Expression
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-alcoholic Fatty Liver Disease Parametric PET (FLiPP) Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-alcoholic Fatty Liver Disease (NAFLD)|Non-alcoholic Steatohepatitis (NASH)
Interventions: RADIATION: Fluorodeoxyglucose (FDG) positron emission tomography (PET)|OTHER: Magnetic resonance imaging (MRI)|RADIATION: PET Explorer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: First In Human Study on Synthetic Surfactant CHF 5633 in Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Respiratory Distress Syndrome in Premature Infants
Interventions: DRUG: synthetic surfactant (CHF5633)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Novel Telemedicine Tools Reduce Disparities Related to Early Identification of Autism
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Developmental Delay
Interventions: OTHER: Telehealth-Screening Tool for Autism in Toddlers (STAT)|OTHER: Telehealth-Autism Spectrum Disorder-Pediatrics (ASD-PEDS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Dentistry United to Extinguish Tobacco
Status: COMPLETED
Conditions: Tobacco Use Treatment
Interventions: BEHAVIORAL: Audit and performance feedback (PF)|BEHAVIORAL: Financial Incentive (P4P)|BEHAVIORAL: Current Best Practices (CBP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Evaluate ISV-305 Compared to Vehicle for Treatment of Inflammation and Pain Associated With Cataract Surgery
Status: COMPLETED
Conditions: Inflammation and Pain Associated With Cataract Surgery
Interventions: DRUG: ISV-305|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Addition of Pyridoxine to Prednisolone in Infantile Spasms
Status: COMPLETED
Conditions: Infantile Spasms
Interventions: DRUG: Pyridoxine plus prednisolone|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aprepitant in Preventing Nausea and Vomiting in Patients Undergoing Chemotherapy and Radiation Therapy for Pancreatic Cancer
Status: COMPLETED
Conditions: Extrahepatic Bile Duct Cancer|Nausea|Vomiting|Stage II Pancreatic Cancer|Stage III Pancreatic Cancer|Stage IV Pancreatic Cancer
Interventions: DRUG: aprepitant|DRUG: gemcitabine hydrochloride|DRUG: capecitabine|DRUG: fluorouracil|PROCEDURE: radiation therapy|OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment|PROCEDURE: nausea and vomiting therapy|PROCEDURE: management of therapy complications
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Xeloda (Capecitabine) Compared With 5-Fluorouracil in Combination With Low-Dose Leucovorin in Patients Who Have Undergone Surgery for Colon Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: 5-Fluorouracil|DRUG: Leucovorin|DRUG: Capecitabine [Xeloda]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fit-Joints: Getting Fit for Hip or Knee Replacement
Status: COMPLETED
Conditions: Hip Osteoarthritis|Knee Osteoarthritis
Interventions: OTHER: Multi-Modal Frailty Intervention|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Xerostomia in Patients With a Life-limiting Condition or Frailty
Status: NOT_YET_RECRUITING
Conditions: Xerostomia|Dry Mouth
Interventions: DRUG: Pilocarpine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Laparoscopic Splenectomy and Azygoportal Disconnection on Liver Reserve Function for Cirrhosis Patients
Status: RECRUITING
Conditions: Cirrhosis, Liver|Splenectomy; Status|Portal Hypertension
Interventions: PROCEDURE: Laparoscopic splenectomy and azygoportal disconnection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BCMA CAR-T Cell Therapy in High-risk NDMM Patients With Positive MRD After First-line ASCT
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: anti-BCMA CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Ultra-fractionated Stereotactic Adaptive Radiotherapy for Metastatic Cervical Cancer
Status: RECRUITING
Conditions: Stage IV Cervical Cancer FIGO 2018|Adenosquamous Carcinoma of Cervix|Cervical Cancer|Metastasis
Interventions: RADIATION: Ultra-fractionated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Centered Mobile Health Technology Enabled Atrial Fibrillation Management
Status: COMPLETED
Conditions: Atrial Fibrillation|Behavior
Interventions: COMBINATION_PRODUCT: Corrie Virtual Atrial Fibrillation Management Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Motivational Interviewing to Improve Self Management in Youth With Type 1 Diabetes
Status: COMPLETED
Conditions: type1diabetes
Interventions: OTHER: Motivational interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Does Cediranib With Paclitaxel, or Cediranib and Olaparib, Treat Advanced Endometrial Cancer Better Than Paclitaxel?
Status: UNKNOWN
Conditions: Carcinosarcoma|Endometrial Neoplasms
Interventions: DRUG: Paclitaxel|DRUG: Cediranib|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Mood Effects of Varenicline (Chantix) in Depressed Outpatient Smokers
Status: COMPLETED
Conditions: Depressive Disorder|Smoking
Interventions: DRUG: fixed dose varenicline|DRUG: varenicline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI Study of High Definition Transcranial Electrical Stimulation in Chronic Tinnitus (MRI HDtES-T)
Status: COMPLETED
Conditions: Tinnitus, Subjective
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral Azithromycin to Prevent Stillbirths and Infant Mortality in Mali
Status: ACTIVE_NOT_RECRUITING
Conditions: Stillbirths and Infant Mortality
Interventions: DRUG: Azithromycin to pregnant women|DRUG: Azithromycin to infants|OTHER: Placebo to pregnant women|OTHER: Placebo to infants|OTHER: No intervention to pregnant women
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Long-term (3 Months) Safety of Femtosecond-laser Assisted Cataract Surgery
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Femtosecond laser cataract surgery|DEVICE: Manual cataract surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Noninvasive Vagus Nerve Stimulation on Functional Status in Ischemic Stroke
Status: RECRUITING
Conditions: Stroke, Ischemic|Hemiplegia|Hemiparesis;Poststroke/CVA
Interventions: DEVICE: transcutaneous auricular vagus nerve stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: He Purongo Mo Nga Kai Hei Arai i Te Matehuka - Dietary Diabetes Prevention Study for Maori
Status: COMPLETED
Conditions: Insulin Resistance
Interventions: BEHAVIORAL: moderate carbohydrate, high protein diet (MCHP)|BEHAVIORAL: high carbohydrate-high fibre (HCHF) diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zibotentan and Dapagliflozin for the Treatment of CKD (ZENITH-CKD Trial)
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Zibotentan|DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Perception of Facial Expressions Following Correction of Wrinkles and Folds
Status: COMPLETED
Conditions: Wrinkles and Folds in Lower Face
Interventions: DEVICE: Emervel Classic Lidocaine|DEVICE: Emervel Deep Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sodium Nitrite on Renal Function and Blood Pressure in Hypertensive Versus Healthy Subjects
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: Sodium nitrite|DRUG: Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gastric Emptying of High Calorie Liquid Meals
Status: COMPLETED
Conditions: Gastric Emptying
Interventions: DIETARY_SUPPLEMENT: Intervention #1: ProvideXtra Drink|DIETARY_SUPPLEMENT: Intervention #2: Fresubin Energy Drink|DIETARY_SUPPLEMENT: Intervention #3: Generic Glucose Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Measuring the Balance Improvement on Multiple Sclerosis Patients After a Short Training Period With an APOS (All Phase Of Step Cycle) Kit
Status: UNKNOWN
Conditions: Multiple Sclerosis|Balance|Cerebelar Impairment
Interventions: DEVICE: APOS shoe kit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Relative Biological Availability and the Effect of Food on the Drug Levels of Danicamtiv in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Danicamtiv
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Open-Label Study to Evaluate the Safety and Efficacy of Ombitasvir/ABT-450/Ritonavir Co-administered With Ribavirin (RBV) in Adults With Genotype 4 Chronic Hepatitis C Virus (HCV) Infection and Cirrhosis (AGATE-1)
Status: COMPLETED
Conditions: Hepatitis C Virus
Interventions: DRUG: ombitasvir/paritaprevir/ritonavir|DRUG: ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of UDCA on the New Onset Diabetes and Glucose Intolerance Induced by Statin
Status: RECRUITING
Conditions: Diabetes Mellitus
Interventions: DRUG: UDCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Dexmedetomidine for Delirium Prevention in Mechanically Ventilated Septic Patients
Status: UNKNOWN
Conditions: Adult|Intensive Care Unit|Sepsis|Mechanical Ventilation|Delirium|Dexmedetomidine
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo (normal saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Two Prophylactic Schedules (Prulifloxacin Versus Phosphomycin)
Status: UNKNOWN
Conditions: Urinary Tract Infection
Interventions: DRUG: prulifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Laser Verses Conventional Circumferential Supracrestal Fiberotomy in Orthodontic Extrusion for Crown Lengthening
Status: RECRUITING
Conditions: Circumferential Supracrestal Fiberotomy|Orthodontic Extrusion|Crown Lengthening
Interventions: PROCEDURE: conventional circumferential supracrestal fiberotomy|PROCEDURE: laser circumferential supracrestal fiberotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Deep-fried Chocolate Bar or Porridge on Cerebral Blood Flow
Status: UNKNOWN
Conditions: Effect on Cerebrovascular Reactivity
Interventions: DIETARY_SUPPLEMENT: chocolate bar|DIETARY_SUPPLEMENT: Porridge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prostatic Urethral Lift in Subject With Acute Urinary Retention
Status: COMPLETED
Conditions: Acute Urinary Retention|Benign Prostatic Hyperplasia
Interventions: DEVICE: UroLift System Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroimaging and Neurocognitive Assessment and Response to Sapropterin Dihydrochloride Treatment in Phenylketonuria
Status: WITHDRAWN
Conditions: PKU
Interventions: DIETARY_SUPPLEMENT: diet|DRUG: sapropterin dihydrochloride|DRUG: sapropterin dihydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Addition of Short Course of Prednisolone to Gluten Free Diet in Naive Celiac Disease Patients
Status: COMPLETED
Conditions: Celiac Disease
Interventions: DRUG: Prednisolone and Gluten free diet|BEHAVIORAL: Gluten free diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Folic Acid Supplementation in Acute Watery Diarrhea Among Children Under 5 Years of Age
Status: UNKNOWN
Conditions: Diarrhoea;Acute
Interventions: DRUG: L-Methylfolate Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Low Power Laser Therapy As Prevention Of Oral Mucositis And Oropharyngeal Pain In Patients Undergoing Allogenetic HSCT
Status: RECRUITING
Conditions: Hematopoietic Stem Cell Transplantation|Low-Level Light Therapy|Stomatitis
Interventions: PROCEDURE: Double low-power laser therapy simultaneous applicated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CMV pp65 Specific T Cell Adoptive Immunotherapy in Allogeneic Stem Cell Transplantation for Malignant Disease
Status: TERMINATED
Conditions: Allogeneic Stem Cell Transplantation
Interventions: BIOLOGICAL: CMV pp65 Specific T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Mulligan's Mobilization With and Without Clamshell Exercises in Sacroiliac Joint Dysfunction
Status: COMPLETED
Conditions: Sacroiliac Joint Somatic Dysfunction|Pain|Disability Physical|Treatment
Interventions: OTHER: Mulligan mobilization|OTHER: clamshell exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Effectiveness of Montelukast Sodium With Comparator in Mild to Moderate Persistent Asthmatics (0476-329)
Status: COMPLETED
Conditions: Asthma|Allergic Rhinitis
Interventions: DRUG: MK0476; montelukast sodium/Duration of Treatment: 16 weeks|DRUG: Comparator: theophylline ER/Duration of Treatment: 16 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Using Bougie or Cooled Nasogastric Tube to Facilitate Nasotracheal Intubation
Status: COMPLETED
Conditions: Intubation Complication
Interventions: DEVICE: bougie|DEVICE: Nasogastric(NG) tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Omitting Clinical Target Volume in Radical Treatment of Unresectable Stage III Non-small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Immunotherapy|Intensity Modulated Radiation Therapy|Radiotherapy|NSCLC
Interventions: RADIATION: IMRT+adjuvant immunotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Neuromuscular Blockade's Monitoring and Clinical Assessment During Cisatracurium Paralysis in Critically Ill Patients
Status: COMPLETED
Conditions: Critical Illness
Interventions: DRUG: Cisatracurium's monitoring by TOF (train-of-four) WATCH device.|DRUG: clinical assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement of Respiratory Admittance for Pediatric Asthma Diagnosis
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Salbutamol|PROCEDURE: Forced oscillation technique|PROCEDURE: Plethysmography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC