pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Usefulness of Lung Ultrasound in Ambulatory Management of Patients With Chronic Heart Failure
Status: TERMINATED
Conditions: Chronic Heart Failure|Lung; Congestive|Acute Decompensated Heart Failure
Interventions: DIAGNOSTIC_TEST: Lung ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab Plus Etoposide and Platinum in Small Cell Bladder Cancer
Status: RECRUITING
Conditions: Small Cell Neuroendocrine Carcinoma of Bladder|Bladder Cancer|Urothelial Carcinoma Bladder
Interventions: DRUG: Atezolizumab|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Etoposide|PROCEDURE: Cystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of the Loading Dose Administrated Via Epidural Needle or Epidural Catheter for Labor Analgesia
Status: COMPLETED
Conditions: Labor Pain
Interventions: PROCEDURE: epidural needle|PROCEDURE: epidural catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Modified Anti-tubercular Regimens in Treatment of Tuberculosis in Patients With Underlying Compensated and Decompensated Chronic Liver Disease
Status: UNKNOWN
Conditions: Chronic Liver Disease With Tuberclosis
Interventions: DRUG: 2HRZE/4HR|DRUG: 2HRLE/4HR|DRUG: 9HLE|DRUG: 9RLE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Long Term Efficacy and Tolerability of ART FILLER® Volume and Lips
Status: COMPLETED
Conditions: Aging
Interventions: DEVICE: Art Filler Volume|DEVICE: Art Filler Lips
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigation of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2245035 in Healthy Volunteers and Allergic Rhinitics.
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: DRUG: 2 ng GSK2445053|DRUG: 20ng GSK2445053|DRUG: 100ng GSK2445053|DRUG: 200ng GSK2445053|DRUG: 400ng GSK2445053|DRUG: 1000ng GSK2445053|DRUG: 2000ng GSK2445053|DRUG: 4000ng GSK2445053|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Center Study Evaluating the Possible Effect of Virtual Reality Spectacles on Pain Following Total Knee Replacement Surgery
Status: UNKNOWN
Conditions: Pain Post Joint Arthroplasty
Interventions: DEVICE: Virtual reality glasses|DEVICE: No VR glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CMP-001 and INCAGN01949 for Patients With Stage IV Pancreatic Cancer and Other Cancers Except Melanoma
Status: TERMINATED
Conditions: Locally Advanced Malignant Solid Neoplasm|Metastatic Pancreatic Adenocarcinoma|Stage IV Pancreatic Cancer AJCC v8|Unresectable Malignant Solid Neoplasm
Interventions: BIOLOGICAL: Agonistic Anti-OX40 Monoclonal Antibody INCAGN01949|DRUG: VLP-encapsulated TLR9 Agonist CMP-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy & Combi in Metastatic Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: RADIATION: Palliative radiotherapy|DRUG: Dabrafenib and trametinib (combination)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Fluoride and Laser Application on the Prevention of Sensitivity in Bleached Teeth
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: DEVICE: Low Level Laser Therapy|DRUG: 1.1% Sodium Fluoride|DRUG: In-office dental bleaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Using Telehealth to Address Alcohol Misuse in HIV Care
Status: RECRUITING
Conditions: Alcohol Drinking|HIV Viremia
Interventions: BEHAVIORAL: Brief Intervention|BEHAVIORAL: Telehealth Counseling|BEHAVIORAL: Text messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ABLE: Abilify in Bipolar Disorder for Long-term Effectiveness
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: aripiprazole|DRUG: valproate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proton Boost for Locally Advanced HEAD AND NECK TUMORS
Status: COMPLETED
Conditions: Epithelial Tumor, Malignant|Neuroendocrine Tumors
Interventions: RADIATION: external beam proton radiation therapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of ApneaLink Air Home Sleep Testing in the Diagnosis of Obstructive Sleep Apnea in Adolescent Children
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: ApneaLink Air
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tolerance and Pharmacokinetics of T0001 in Healthy Adult Chinese Volunteers
Status: COMPLETED
Conditions: Rheumatic Diseases
Interventions: DRUG: T0001，10mg|DRUG: T0001，20mg|DRUG: T0001，35mg|DRUG: T0001，50mg|DRUG: T0001，65mg|DRUG: T0001，75mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Copanlisib as a Potential Targeted Treatment in Cancers With PIK3CA Mutations (MATCH-Subprotocol Z1F)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lymphoma|Advanced Malignant Solid Neoplasm|Hematopoietic and Lymphatic System Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Multiple Myeloma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Computed Tomography|DRUG: Copanlisib Hydrochloride|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of GW679769 on Sleep and Cognitive Function in Subjects With Primary Insomnia
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: DRUG: GW679769|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Predicting Medication Response in Obsessive Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: DRUG: clomipramine|DRUG: escitalopram|DRUG: duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study of GSK4527363 in Healthy Participants, Systemic Lupus Erythematosus (SLE) Participants and Healthy Chinese and Japanese Participants
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: GSK4527363|DRUG: Placebo matching GSK4527363|DRUG: Belimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Experience With H.P. Acthar Gel Treatment of Patients With Nephrotic Syndrome/Proteinuria Due to Various Etiologies and Its Effect on Podocyte Function
Status: UNKNOWN
Conditions: Decrease of Proteinuria With H.P. Acthar Gel and Its Effects on Clinical and Podocyte Function
Interventions: DRUG: Acthar
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intravascular Near Infrared Spectroscopy (NIRS) Bifurcation - Lipid Core Plaque Shift Study
Status: COMPLETED
Conditions: Angina Pectoris|Angina, Unstable|Atherosclerosis|Coronary Artery Disease
Interventions: DEVICE: LipiScan Coronary Imaging Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation Nutrition Education Intervention on Pulse and Cereal Mix for Complementary Food in Southern Ethiopia
Status: COMPLETED
Conditions: Dietary Habits|Health Knowledge, Attitudes, Practices|Wasting
Interventions: OTHER: enhanced education on pulse use in complementary foods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dry Needling and Lateral Hip Pain (GTPS)
Status: RECRUITING
Conditions: Trochanteric Bursitis
Interventions: DEVICE: Dry Needling|DEVICE: Lasertherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-Time-in-Human (FTIH) Study to Evaluate the Safety, Tolerability and Pharmacokinetics (PK) of VH4011499 in Healthy Participants
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: VH4011499|DRUG: Placebo|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Adjustment Trial of SK-1403 in Hemodialysis Patients With Secondary Hyperparathyroidism
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism
Interventions: DRUG: Dose-adjusted SK-1403
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioelectrical Impedance Analysis as a Bedside Tool to Estimate Volume of Distribution of Hydrophilic Antimicrobials in Critically Ill Patients
Status: COMPLETED
Conditions: Electric Impedance|Pharmacokinetics|Capillary Leak Syndrome
Interventions: DRUG: Monitor antibiotic exposure (PK profile)|DEVICE: Bioelectrical impedance analysis to measure body composition
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intravascular Ultrasound for the Evaluation of Malperfusion Syndrome in the Setting of Acute Aortic Dissection
Status: UNKNOWN
Conditions: Aortic Dissection|Perfusion; Complications
Interventions: DEVICE: Intravascular ultrasound 0.035 PV IVUS catheter (Volcano Therapeutics, Rancho Cordova, CA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Nurse-led Transtheoretical Model-Based Video Exercise Trainings on Fall Risk to Elderly People Living in Nursing Homes
Status: ENROLLING_BY_INVITATION
Conditions: Risk of Falling in the Elderly
Interventions: OTHER: Transtheoretic Model Based Video Exercise Training|OTHER: Standard Maintenance Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Actinic Keratoses Treatment With Metvix® in Combination With Light
Status: COMPLETED
Conditions: Actinic Keratoses
Interventions: DRUG: Metvix®|PROCEDURE: Photodynamic Therapy Blue light|PROCEDURE: Photodynamic Therapy Daylight
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Intravenous Doses of Activated Recombinant Human Factor VII in Healthy Volunteers
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A With Inhibitors|Haemophilia B With Inhibitors|Healthy
Interventions: DRUG: activated recombinant human factor VII|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of TMBCZG in Mild to Moderate Vascular Dementia
Status: COMPLETED
Conditions: Vascular Dementia
Interventions: DRUG: TMBCZG|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Mesenchymal Stem Cells in the Treatment of Severe Acute Kidney Injury
Status: UNKNOWN
Conditions: Acute Kidney Injury|Mesenchymal Stem Cells
Interventions: BIOLOGICAL: Mesenchymal stem cells|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Brain Stimulation for Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury|Diffuse Axonal Injury
Interventions: OTHER: Active Coil|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Prophylactic Swallowing Therapy in Patients Undergoing Definitive Chemoradiation for Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Oropharynx Cancer
Interventions: OTHER: Prophylactic Swallowing Home Exercise Program|OTHER: Clinician-Directed Prophylactic Swallowing Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CARDIO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)
Status: ACTIVE_NOT_RECRUITING
Conditions: Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)
Interventions: DRUG: Eplontersen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: One Month Dispensing Study Comparing the Clinical Performance of the Comfilcon A Sphere Lenses Compared to Comfilcon A Asphere Lenses.
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: comfilcon A sphere lens (control)|DEVICE: comfilcon A asphere lens (test)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Efficacy of Three Doses of Live Attenuated, Oral Rotavirus Vaccine 116E
Status: RECRUITING
Conditions: Rotavirus Gastroenteritis
Interventions: DRUG: ROTAVAC 5D|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dosage of Epidural Morphine in Elderly Patients
Status: COMPLETED
Conditions: Age Problem|Abdominal Cancer
Interventions: DRUG: 1.5 mg of Morphine Sulfate|DRUG: Normal saline|DRUG: 3 mg of Morphine Sulfate|DRUG: 4.5 mg of Morphine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vaccine Therapy in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Intraocular Melanoma|Malignant Conjunctival Neoplasm|Melanoma (Skin)
Interventions: BIOLOGICAL: Peptide vaccine|BIOLOGICAL: GM-CSF|BIOLOGICAL: PF3512676
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Escitalopram in Depressive Patients With Acute Coronary Artery Syndrome
Status: COMPLETED
Conditions: Depressive Disorder|Coronary Disease
Interventions: DRUG: Escitalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Billroth-I and Roux-en-Y Reconstruction After Distal Subtotal Gastrectomy
Status: UNKNOWN
Conditions: Gastrectomy
Interventions: PROCEDURE: Billroth-I|PROCEDURE: Roux en Y
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the GORE PV1 Device in Patients With Pulmonary Valve Dysfunction
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Defects, Congenital|Tetralogy of Fallot|Pulmonary Valve Insufficiency|Pulmonary Valve Stenosis
Interventions: DEVICE: GORE PV1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Hepatitis A Virus Induced Acute Acalculous Cholecystitis Diagnosed Postoperatively: Case Report
Status: COMPLETED
Conditions: Acute Acalculous Cholecystitis
Interventions: OTHER: Laparoscopic cholecystectomy for hepatitis A induced acute acalculous cholecystitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sorafenib in Treating Patients With Advanced or Metastatic Cancer of the Urinary Tract
Status: COMPLETED
Conditions: Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter|Recurrent Bladder Cancer|Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter|Regional Transitional Cell Cancer of the Renal Pelvis and Ureter|Stage III Bladder Cancer|Stage IV Bladder Cancer|Transitional Cell Carcinoma of the Bladder
Interventions: DRUG: sorafenib tosylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Combination Therapy to Treat Uncomplicated Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: naltrexone and bupropion SR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Indirect Pulp Treatment in Primary Molars
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: Indirect pulp treatment using Dycal (TM)|DRUG: Indirect pulp treatment using Vitrebond (TM )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stress Induced by the COVID-19 Pandemic and Nonconfinement: Study of Anxiety Factors and Potential Effects on Immunity.
Status: TERMINATED
Conditions: Stress Disorder
Interventions: DIAGNOSTIC_TEST: Generalized Anxiety Disorder-7 (GAD 7)|DIAGNOSTIC_TEST: Background questionnaire|DIAGNOSTIC_TEST: Impact of COVID-19 questionnaire|DIAGNOSTIC_TEST: Confinement and Communication During the COVID-19 Pandemic|DIAGNOSTIC_TEST: Mental Health questionnaire|DIAGNOSTIC_TEST: Patient Health Questionnaire (PHQ-9)|DIAGNOSTIC_TEST: Post Traumatic Stress Disorder questionnaire (PTSD-8)|DIAGNOSTIC_TEST: Experiences in Close Relationship Scale questionnaire (ECR-S)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Quadratus Lumborum Intramuscular and Transmuscular in Postoperative Pain
Status: COMPLETED
Conditions: Pain, Postoperative|Pain, Acute|Cesarean Section Complications
Interventions: OTHER: Quadratus lumborum block after C-section surgery as postoperative pain management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can Objective Compliance Monitoring Increase Mandibular Advancement Device Usage in Obstructive Sleep Apnea Patients
Status: TERMINATED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: SomnoDent Flex with DentiTrac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Zoledronic Acid in Decrease the Lung Metastatic Rate of Osteosarcoma
Status: UNKNOWN
Conditions: Lung Metastases|Tumor Necrosis
Interventions: DRUG: Zoledronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Cell Therapy in Diabetic Patients With ST-Segment Elevation Myocardial Infarction(STEMI)
Status: UNKNOWN
Conditions: Left Ventricular Function Systolic Dysfunction|Left Ventricular Function Diastolic Dysfunction|Death|Myocardial Reperfusion Injury
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of Ex Vivo Immunotherapy for Treatment of Aplastic Anemia
Status: UNKNOWN
Conditions: Anemia, Aplastic
Interventions: PROCEDURE: Ex Vivo Immunotherapy|DRUG: Ex vivo immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of GEMOX Combination and Vinorelbine in NSCL Patients
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: oxaliplatine / gemcitabine / Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Safety of Ragweed Mix Given by Intralymphatic Node Injections
Status: TERMINATED
Conditions: Allergic Conjunctivitis|Allergic Rhinitis
Interventions: BIOLOGICAL: Dose Level 1|BIOLOGICAL: Dose Level 2|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ascorbic Acid and Ibuprofen in Infants With Hypoxic Ischemic Encephalopathy
Status: COMPLETED
Conditions: Hypoxic Ischemic Encephalopathy|Perinatal Asphyxia
Interventions: DRUG: Ascorbic acid (vitamin C)|DRUG: Ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Left Atrial Appendage Velocity on Left Atrial Structure and Function After Radiofrequency Ablation Combined With Left Atrial Appendage Occlusion
Status: COMPLETED
Conditions: Left Atrial Appendage Velocity|Left Atrial Structure|Left Atrial Function
Interventions: DEVICE: Transesophageal ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Docetaxel and St. John's Wort in Treating Patients With Solid Tumors That Cannot Be Removed By Surgery
Status: WITHDRAWN
Conditions: Adult Solid Tumor|Breast Cancer|Head and Neck Cancer|Kidney and Urinary Cancer|Male Reproductive Cancer|Thorax and Respiratory Cancer
Interventions: DRUG: Hypericum perforatum|DRUG: docetaxel|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: I/II Phase Study Evaluating M1774 in Combination With Fulvestrant in HR+ and HER2- Advanced Breast Cancers
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: M1774|DRUG: Fulvestrant injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the ECOM™ Monitor for Continuous and Non-invasive Measure of the Cardiac Output in Cardiac Surgery Patients
Status: TERMINATED
Conditions: Cardiac Surgery
Interventions: DEVICE: ECOM™.|DEVICE: Trans-esophageal echography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Sacituzumab Govitecan in Combination With Capecitabine for Advanced Gastrointestinal Cancers After Progression on Standard Therapy
Status: NOT_YET_RECRUITING
Conditions: Gastrointestinal Cancer
Interventions: DRUG: Capecitabine|DRUG: Sacituzumab govetican
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cessation Versus Continuation of Long-term Mepolizumab in Severe Eosinophilic Asthma Patients
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: Mepolizumab 100mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigation of the EndoStim® Lower Esophageal Sphincter (LES) Stimulation System for the Treatment of Reflux
Status: TERMINATED
Conditions: Gastroesophageal Reflux Disease (GERD)|Reflux, Gastroesophageal|Gastroesophageal Reflux|Acid Reflux
Interventions: PROCEDURE: Laparoscopic implantation surgery|DEVICE: EndoStim stimulation for first six months of study|DEVICE: EndoStim stimulation from Month 6 thru end of study|DEVICE: Sham EndoStim stimulation for first six months of study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Antimullerian Hormone Levels on the Inflammatory Index, Phytochemical Index and NRF Nutrient Density
Status: NOT_YET_RECRUITING
Conditions: AMH|Diet Habit|Ovarian Failure|Polycystic Ovary Syndrome
Interventions: BEHAVIORAL: Dietary Inflammatory Index|DIAGNOSTIC_TEST: hormone profile
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Of PF-06817024 In Healthy Subjects, In Patients With Chronic Rhinosinusitis With Nasal Polyps And in Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Healthy|Chronic Rhinosinusitis With Nasal Polyps|Atopic Dermatitis
Interventions: BIOLOGICAL: PF-06817024|OTHER: Placebo for PF-06817024|BIOLOGICAL: PF-06817024|OTHER: Placebo for PF-06817024|BIOLOGICAL: PF-06817024|OTHER: Placebo for PF-06817024|BIOLOGICAL: PF-06817024|OTHER: Placebo for PF-06817024|BIOLOGICAL: PF-06817024|OTHER: Placebo for PF-06817024
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Pathways of Cardiac Remodellation in Patients With Acute and Chronic Left Ventricular Disfunction
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure|Ischemic Cardiomyopathy
Interventions: OTHER: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Low-load Blood Flow Restriction Training in COPD
Status: COMPLETED
Conditions: COPD|Muscle Weakness
Interventions: OTHER: Low-load blood flow restriction training|OTHER: Usual outpatient pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of Novel Physiological CMR Methods in Health and Disease
Status: SUSPENDED
Conditions: Heart Failure|Pulmonary Hypertension|Myocardial Infarction|Coronary Artery Disease
Interventions: OTHER: intravenous fluid challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-389949
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: ACT-389949 1 mg|DRUG: ACT-389949 5 mg|DRUG: ACT-389949 20 mg|DRUG: ACT-389949 50 mg|DRUG: ACT-389949 100 mg|DRUG: ACT-389949 200 mg|DRUG: ACT-389949 500 mg|DRUG: ACT-389949 1000 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate Efficacy and Safety of Povorcitinib in Participants With Nonsegmental Vitiligo (STOP-V2)
Status: RECRUITING
Conditions: NonSegmental Vitiligo
Interventions: DRUG: Povorcitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Ultrasound Guided Corticoanesthetic Injection in Carpal Tunnel Syndrome
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: carpal tunnel corticoanesthetic injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Cervical Stabilization Exercise Training With Telerehabilitation in Individuals With Migraine
Status: UNKNOWN
Conditions: Migraine
Interventions: OTHER: Cervical Stabilization Exercise|OTHER: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Pharmacology Study of TS-143 in Nondialysis and Hemodialysis Patients With Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: TS-143
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lubricating Eye Drops After Routine Cataract Surgery
Status: COMPLETED
Conditions: Dry Eye|Cataract
Interventions: DRUG: AEONTM Repair and AEONTM Protect Plus lubricating eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Study of Irinotecan,Oxaliplatin Plus TS-1 in Untreated Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Colorecal Neoplasms|Secondary
Interventions: DRUG: S-1, irinotecan, oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 2nd Line Erlotinib Treatment With (Out) Chemotherapy of Advanced Non Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: erlotinib plus docetaxel or pemetrexed|DRUG: erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interferon Beta 1a in Hospitalized COVID-19 Patients
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Interferon Beta-1A|DRUG: Lopinavir / Ritonavir|DRUG: Single Dose of Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Phosphodiesterase 4 Inhibitor Roflumilast as an Adjunct to Antidepressants in Major Depressive Disorder Patients
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Roflumilast 500Mcg Tab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation for the Treatment of Severe Acute Gut Graft-Versus-Host Disease
Status: WITHDRAWN
Conditions: Acute Graft Versus Host Disease|Gastrointestinal Tract Acute Graft Versus Host Disease|Severe Gastrointestinal Tract Acute Graft Versus Host Disease|Steroid Resistant Gastrointestinal Tract Acute Graft Versus Host Disease
Interventions: DRUG: Fecal Microbiota Transplantation Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Prospective, Randomized, Open-label, Active-Controlled Clinical Trial for Safety Evaluation of Intra-articular Injection of RegenoGel-SP for the Treatment of Moderate to Severe Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: intra-articular administration of RegenoGel-SP or hyaluronic acid (HA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Optimize Insulin Treatment by Basal Regimen With Insulin Glargine in Type-2-Diabetic Patients Previously Uncontrolled on Premixed Insulin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Endoscopic Infection Rate Notifications to Improve the Delivery of Care
Status: COMPLETED
Conditions: Infection
Interventions: OTHER: Option 1: National comparison|OTHER: Option 2: National comparison with benchmarking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Apatinib Plus Docetaxel as 2nd Line Treatment in Patients With Advanced Lung Adenocarcinoma Harboring Wild-type EGFR
Status: UNKNOWN
Conditions: Lung Adenocarcinoma
Interventions: DRUG: Apatinib (250 mg/d) + Docetaxel (60 mg/m2)|DRUG: Apatinib (500 mg/d) + Docetaxel (60 mg/m2)|DRUG: Apatinib (750 mg/d) + Docetaxel (60 mg/m2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture and Chinese Herbal Medicine to Improve Live Birth Rate of in Vitro Fertilization (IVFAct)
Status: UNKNOWN
Conditions: In Vitro Fertilization
Interventions: OTHER: Acupuncture and Chinese Herbal Medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Active Temperature Management After Cardiac Surgery and Its Effect on Postoperative Cognitive Dysfunction
Status: WITHDRAWN
Conditions: Cardiac Surgery|Post-operative Cognitive Dysfunction|Fever
Interventions: DEVICE: Rapr Rounds Hyper/Hypothermia Wraps|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Biomarker-Guided, Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study of Liafensine in Patients With Treatment-Resistant Depression
Status: COMPLETED
Conditions: Treatment Resistant Depression
Interventions: DRUG: Liafensine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Feasibility of N-of-1 Trials in Children With Hypertension and Chronic Kidney Disease
Status: COMPLETED
Conditions: Hypertension|Chronic Kidney Diseases
Interventions: PROCEDURE: n-of-1 trial guided clinical decision making
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Volatile Organic Compounds in Exhaled Air and Sweat: Interest in Rapid Screening for COVID-19 Infection.
Status: UNKNOWN
Conditions: Covid19
Interventions: DEVICE: Volatile Organic Compounds analysis (e-noses)|OTHER: Canine odor detection of Volatile Organic Compounds|DEVICE: Volatile Organic Compounds analysis (mass spectrometry)|DEVICE: Volatile Organic Compounds analysis in sweat (mass spectrometry)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Testing for Tuberculosis in the United Kingdom HIV Infected Population
Status: UNKNOWN
Conditions: HIV|Latent Tuberculosis
Interventions: RADIATION: Chest radiograph|PROCEDURE: Blood interferon gamma release assay|PROCEDURE: Tuberculin skin testing (TST)|PROCEDURE: Sputum induction for mycobacterial microscopy and culture|OTHER: Mycobacterium tuberculosis polymerase chain reaction testing|PROCEDURE: Spirometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1 Trial of Perfusion Induced Systemic Hyperthermia (PISH) Over Multiple Cycles for Terminal Ovarian Cancer
Status: SUSPENDED
Conditions: Ovarian Cancer
Interventions: DEVICE: ThermalCore Hyperthermia System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Right Ventricular Echocardiography in caRdiac SurgEry
Status: COMPLETED
Conditions: Right Ventricular Dysfunction
Interventions: OTHER: Change in preload and afterload|OTHER: Inspired oxygen|OTHER: Pacemaker mode
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Comparing the Safety and Effectiveness of Cartilage Cell Injected Into the Lumbar Disc as Compared to a Placebo
Status: TERMINATED
Conditions: Degenerative Disc Disease
Interventions: BIOLOGICAL: NuQu|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy of Gastric Cancer With Autologous Tumor Derived Heat Shock Protein gp96
Status: UNKNOWN
Conditions: Gastric Carcinoma
Interventions: BIOLOGICAL: autologous gp96 vaccination|DRUG: Oxaliplatin+S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electro-thumbtack Needle Therapy for Chronic Neck Pain
Status: UNKNOWN
Conditions: Neck Pain
Interventions: PROCEDURE: Electro-thumbtack Needle Therapy|PROCEDURE: Sham electro-thumbtack needle therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-pocket Application of Tea Tree Oil Gel in the Treatment of Stage-2 Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: PROCEDURE: Scaling and Root Planing|DRUG: Scaling and Root Planing with tea tree oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Multi-directional Power Toothbrush on Recession
Status: COMPLETED
Conditions: Gingival Recession
Interventions: DEVICE: Toothbrushing with manual toothbrush|DEVICE: Toothbrushing with power toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Time Serial Analysis on Preemptive Analgesia of Preoperative Topical Diclofenac and Ketorolac in Photorefractive Keratectomy(PRK)
Status: COMPLETED
Conditions: Myopes Who Have Undergone PRK.
Interventions: DRUG: topical ketorolac 0.5% (Acular®, Allergan Inc, Irvine, CA)|DRUG: topical diclofenac 0.1% (Voltaren®, Novartis, Bern, Switzerland)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Self Help Plus and Post-Migration Living Difficulties Support Intervention
Status: NOT_YET_RECRUITING
Conditions: Psychological Distress|Psychological Trauma|Mental Health|Refugee Health
Interventions: BEHAVIORAL: SH+ combined with a session for PMLD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of GF-001001-00 Cream in Secondarily-Infected Traumatic Lesions
Status: COMPLETED
Conditions: Secondarily Infected Traumatic Lesions
Interventions: DRUG: GF-001001-00|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Hyperthermic Intraperitoneal Chemotherapy After Resection of Pancreascarcinoma
Status: UNKNOWN
Conditions: Adenocarcinomas of the Pancreas
Interventions: DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NCCL Direct Composite Restoration Performance With Self-Etch and Multimode Adhesives
Status: COMPLETED
Conditions: Dental Adhesives/Restorations Performance
Interventions: DEVICE: G1-Control: Futurabond®DC-SE (FBDC_SE)|DEVICE: G2-Control: Futurabond®DC_SE_EE|DEVICE: G3: Futurabond® U - ER (FBU_ER)|DEVICE: G4: Futurabond® U - SE (FBU_SE)|DEVICE: G5: Adhese® Universal - ER (ADU_ER)|DEVICE: G6: Adhese® Universal - SE (ADU_SE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Hyperbaric Oxygen, Oxidative Stress, NO Bioavailability and Tissue Oxygenation
Status: COMPLETED
Conditions: Diabetic Foot Ulcers
Interventions: DRUG: N-acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin in Pulmonary Arterial Hypertension
Status: RECRUITING
Conditions: Idiopathic Pulmonary Arterial Hypertension
Interventions: DRUG: Empagliflozin 10 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of ALG- 1001 to Treat Diabetic Macular Edema
Status: WITHDRAWN
Conditions: Diabetic Macular Edema
Interventions: DRUG: ALG-1001|DRUG: ALG-1001|DRUG: ALG-1001|DRUG: ALG-1001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Social Media and Suicidal Behaviour - Study 1
Status: RECRUITING
Conditions: Suicidal Behaviour
Interventions: BEHAVIORAL: Reading journalistic posts and articles on social media on nature|BEHAVIORAL: Reading journalistic posts and articles on social media on deaths by suicide|BEHAVIORAL: Reading journalistic posts and articles on social media on traffic-related deaths
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Liposomal Bupivacaine for Pain Control After Total Shoulder Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis|Arthropathy|Shoulder Pain|Closed Fracture Proximal Humerus, Four Part
Interventions: DRUG: Liposomal bupivacaine|DRUG: Interscalene Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Argatroban Infusion in Conduction Disturbances
Status: COMPLETED
Conditions: Stable Coronary Artery Disease (CAD)|Unstable Angina (Troponin Negative)
Interventions: DRUG: Argatroban
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Cryoablation Versus Partial Nephrectomy for T1b Renal Tumor
Status: RECRUITING
Conditions: Renal Tumor
Interventions: PROCEDURE: Renal biopsy|PROCEDURE: Cryoablation|PROCEDURE: Partial nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Neck Collar, Act-as-Usual, and Active Mobilisation Early After a Whiplash Injury
Status: COMPLETED
Conditions: Whiplash Injury
Interventions: BEHAVIORAL: neck collar; advice to act-as-usual; active mobilisation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Placebo-controlled, Proof-of-concept Study to Evaluate the Safety and Efficacy of Lanifibranor Alone and in Combination With SGLT2 Inhibitor EmpaGliflozin in patiEnts With NASH and Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis|Diabetes Mellitus, Type 2
Interventions: DRUG: IVA337|DRUG: Placebo|DRUG: Empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of V.A.C. Veraflo Therapy in Wounds Requiring Debridement Within an Orthopedic Practice
Status: COMPLETED
Conditions: Wounds and Injuries
Interventions: DEVICE: NPWT with Instillation|DEVICE: NPWT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mean Healing Time of Wound After Vacuum Assisted Closure (VAC) Versus Conventional Dressing in Diabetic Foot Ulcer Patients
Status: COMPLETED
Conditions: Diabetic Foot Ulcer|Healing Delayed|Wound; Foot|Diabetes Mellitus
Interventions: PROCEDURE: Vacuum assisted closure VAC vs conventional dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical Protocol of BCG-PPD in Healthy People
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: BCG-PPD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Oral Apixaban (Eliquis) Versus Enoxaparin (Lovenox) for Thromboprophylaxis in Women With Suspected Pelvic Malignancy
Status: COMPLETED
Conditions: Gynecologic Cancer|Venous Thromboembolism
Interventions: DRUG: Oral apixaban|DRUG: Subcutaneous enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Gore VIABAHN BX for Treatment of Occlusive Disease in the Iliac Arteries.
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Stenting of the Common and/or External Iliac Arteries
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Granisetron Transdermal Patch for Prophylaxis of Delayed CINV
Status: UNKNOWN
Conditions: Chemotherapy-induced Nausea and Vomiting (CINV)
Interventions: DRUG: Granisetron transdermal patch|DRUG: Palonosetron|DRUG: Aprepitant|DRUG: Fosaprepitant|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT