pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Anti-aging and Anti-oxidant Efficacy Evaluation of the MelaGene
Status: COMPLETED
Conditions: Aging|Antioxidative Stress
Interventions: DIETARY_SUPPLEMENT: Placebo drink|DIETARY_SUPPLEMENT: MelaGene drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Olverembatinib Combined With Inotuzumab Ozogamicin in the Treatment ph+ ALL With MRD Persistent Positive
Status: NOT_YET_RECRUITING
Conditions: Ph+ ALL|Bone Marrow Transplant|Minimal Residual Disease
Interventions: DRUG: the usage of Olverembatinib combined with Inotuzumab Ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Advanced Care at Home vs. Traditional Brick-and-Mortar Hospital Care in Acutely Ill Adults: A Pragmatic Clinical Trial
Status: ENROLLING_BY_INVITATION
Conditions: Acute Illness
Interventions: OTHER: Advanced Care at Home (ACH)|OTHER: Traditional Brick-and-Mortar Hospitalization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Carfilzomib In Combination With Bendamustine And Dexamethasone In Refractory Or Relapsed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Evaluating a Multidisciplinary Chronic Pain Group Therapy in a Primary Care Setting
Status: COMPLETED
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Living Everyday Above-and-beyond Pain (LEAP)|OTHER: Wait-listed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Piloting a Novel, Mobile Cognitive Training Tool for Patients With Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: OTHER: Computerized Plasticity-Based Adaptive Cognitive Training|OTHER: Commercially available computerized training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acquisition of MI Competence Trough the Training Methods Used in the Swedish County Councils and Municipalities
Status: COMPLETED
Conditions: Competence
Interventions: BEHAVIORAL: Regular MI-training|BEHAVIORAL: Regular MI-training + supervision half|BEHAVIORAL: Regular MI-training + supervision full
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Spinal Cord Stimulation and Respiration After Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries|Spinal Cord Stimulation|Breathing Exercises|Rehabilitation
Interventions: DEVICE: Spinal Cord Epidural Stimulation|OTHER: Respiratory Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of RESOLUTE Zotarolimus-Eluting Stent in Treatment of Chinese Diabetic Coronary Lesions
Status: COMPLETED
Conditions: Coronary Artery Disease|Diabetes
Interventions: DEVICE: Resolute stent treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epirubicin or Not in Patients With TOP2A (Topoisomerase (DNA) II Alpha (170kD)) Normal Early Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Epirubicin, cyclophosphamide and docetaxel|DRUG: docetaxel, cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Child Positioning on Pain During a Lumbar Puncture
Status: COMPLETED
Conditions: Hematological Malignancies
Interventions: OTHER: LP in a seated position then LP in a lying position|OTHER: LP in a lying position then LP in a seated position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Infrared Low-level Laser Therapy Before Intense Progressive Running Test of High-level Soccer Players
Status: COMPLETED
Conditions: Muscle; Fatigue, Heart|Skeletal Muscle Recovery
Interventions: DEVICE: Active PBMT|DEVICE: Placebo PBMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Early VItrectomy in DENse Spontaneous Vitreous HEmorrhage
Status: RECRUITING
Conditions: Spontaneous Vitreous Hemorrhage|Retinal Break|Retinal Detachment
Interventions: PROCEDURE: Early vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Colchicine in High-risk Patients With Acute Minor-to-moderate Ischemic Stroke or Transient Ischemic Attack (CHANCE-3)
Status: COMPLETED
Conditions: Ischemic Stroke|TIA
Interventions: DRUG: Colchicine|DRUG: Placebo colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Predicting Post Extubation Stridor After Maxillomandibular Fixation
Status: RECRUITING
Conditions: Stridor|Larynx Edema
Interventions: DRUG: budesonide|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Population at Risk of Malignant Hyperthermia: Ambispective Cohort.
Status: RECRUITING
Conditions: Hyperthermia, Malignant
Interventions: DIAGNOSTIC_TEST: In vitro contracture test (IVCT)|DIAGNOSTIC_TEST: In vitro test of hypermetabolism in B lymphocytes|DIAGNOSTIC_TEST: Genetic test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of the Efficacy of Digital CBT for Anxiety in Adults With Chronic Musculoskeletal Pain
Status: COMPLETED
Conditions: Pain, Chronic|Pain, Musculoskeletal|Anxiety
Interventions: BEHAVIORAL: dCBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ischemic Postconditioning in Carotid Surgery
Status: RECRUITING
Conditions: Ischemic Postconditioning|Carotid Surgery|Stroke|Carotid Artery Diseases
Interventions: PROCEDURE: Ischemic postconditioning in carotid surgery|PROCEDURE: Eversion Carotid Endarterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Peginterferon Plus Ribavirin Combination Therapy for Hepatitis C Six Months After Onset of Acute Infection
Status: COMPLETED
Conditions: Acute Hepatitis C
Interventions: DRUG: pegylated interferon alpha 2a, ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2 Study of KHK7580 for Secondary Hyperparathyroidism in Patients Receiving Hemodialysis
Status: COMPLETED
Conditions: Hyperparathyroidism
Interventions: DRUG: KHK7580
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy of OLX10010 in Reducing Recurrence of Hypertrophic Scarring After Scar Revision Surgery
Status: COMPLETED
Conditions: Hypertrophic Scar
Interventions: DRUG: OLX10010
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2a, Efficacy and Safety Study of Duvelisib in Mild Asthmatic Subjects
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: IPI-145, a PI3K Inhibitor|DRUG: Placebo to match IPI-145
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Prehabilitation on Markers of Fitness and Frailty in Patients Undergoing Elective Surgery
Status: SUSPENDED
Conditions: Frailty
Interventions: BEHAVIORAL: Combined neuromuscular exercise training and 'sit less, move more' program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Integrated Digital PROM-platform for Cancer Patients During the COVID-19 Pandemic
Status: COMPLETED
Conditions: Covid19|Oncology|PROMs|Chemotherapeutic Toxicity
Interventions: OTHER: ePROMs assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cardiovascular Risk Prevention With a Mediterranean Dietary Pattern Reduced in Saturated Fat
Status: RECRUITING
Conditions: LDL Cholesterol
Interventions: BEHAVIORAL: Cardiovascular Risk Prevention with a Mediterranean Dietary Pattern Reduced in Saturated Fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Upper Extremity Deep-Vein Thrombosis
Status: COMPLETED
Conditions: Deep-Vein Thrombosis
Interventions: DRUG: Dalteparin sodium injection|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of (Chemo)RT-related Dysphagia in HNC Patients Based on Cough-related Acoustic Features
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer|Dysphagia
Interventions: OTHER: Acoustic cough features analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Helicobacter Pylori in Patients With Chronic Tonsillits Prepared for Tonsillectomy
Status: RECRUITING
Conditions: Helicobacter Pylori Infection in Patients With Chronic Tonsillits
Interventions: DIAGNOSTIC_TEST: Rapid urease test for h pylori
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Double-Blind, Controlled Study of Aripiprazole in Co-Morbid Schizophrenia and Cocaine Dependence
Status: UNKNOWN
Conditions: Schizophrenia|Cocaine Dependence
Interventions: DRUG: Aripiprazole|DRUG: Perphenazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mild Hypothermia During Intracranial Aneurysm Clipping
Status: WITHDRAWN
Conditions: Subarachnoid Hemorrhage, Aneurysmal
Interventions: PROCEDURE: Mild hypothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluorescent Intra-operative Tumor Margin Examination
Status: RECRUITING
Conditions: Sarcoma
Interventions: DRUG: Indocyanine green solution administered at 2.0mg/kg.|DEVICE: Stryker SPY-PHI Imaging Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CERAB Technique for Aortoiliac Occlusive Disease
Status: UNKNOWN
Conditions: Aortoiliac Occlusive Disease
Interventions: PROCEDURE: Covered Endovacular Reconstruction of Aortic Bifurcation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Timing of Tracheotomy in Covid-19 Patients
Status: COMPLETED
Conditions: Covid-19|ARDS|Tracheostomy Complication|Respiratory Insufficiency|Corona Virus Infection
Interventions: PROCEDURE: Tracheotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PURETHAL Birch RUSH Study
Status: COMPLETED
Conditions: Allergic Rhinitis|Allergic Rhinoconjunctivitis
Interventions: BIOLOGICAL: PURETHAL Birch, 20.000 AUM/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in HIV1-Positive, Virosuppressed Patients Currently inTreatment With Ritonavir-Boosted Protease Inhibitors (PI/r) Starting Cobicistat-Boosted Darunavir (DRV/c - Rezolsta)
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability and Pharmacokinetic Study of MB12066 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DRUG: MB12066 200mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: The Effect of Mechanical Vibration and ShotBlocker on Pain Levels During Heel Lance in Healthy Term Neonates
Status: COMPLETED
Conditions: Procedural Pain
Interventions: DEVICE: ShotBlocker|DEVICE: Mechanical vibration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase III Study of and Efficacy of Ligelizumab in the Treatment of CSU in Adolescents and Adults Inadequately Controlled With H1-antihistamines.
Status: COMPLETED
Conditions: Chronic Spontaneous Urticaria
Interventions: BIOLOGICAL: Ligelizumab|BIOLOGICAL: Omalizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Home Monitoring on the Clinical Status of Heart Failure Patients With an Impaired Left Ventricular Function
Status: COMPLETED
Conditions: Ventricular Fibrillation|Ventricular Tachycardia|Congestive Heart Failure
Interventions: DEVICE: ICD or CRT-D with Home Monitoring feature deactivated|DEVICE: ICD or CRT-D with Home Monitoring feature activated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Increased Convective Clearance by On-Line Hemodiafiltration on All Cause Mortality in Chronic Hemodialysis Patients
Status: COMPLETED
Conditions: End-stage Renal Disease|Cardiovascular Disease
Interventions: PROCEDURE: on-line hemodiafiltration|PROCEDURE: low flux hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Dalbavancin Compared to Standard of Care Antibiotic Therapy for the Completion of Treatment of Patients With Complicated Bacteremia or Infective Endocarditis
Status: TERMINATED
Conditions: Endocarditis|Bacteremia
Interventions: DRUG: Dalbavancin|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RCT Study of the Gelstix™ Device to Treat Chronic Discogenic Low Back Pain GelStix Study
Status: RECRUITING
Conditions: Degeneration of Lumbar Intervertebral Disc
Interventions: DEVICE: GelStix™ Nucleus Augmentation Device|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Povidone-iodine Antisepsis for Strabismus Surgery
Status: COMPLETED
Conditions: Strabismus|Surgery|Endophthalmitis
Interventions: DRUG: Preoperative conjunctival irrigation with 5% or 1.25% PI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of M5049 in Participants With COVID-19 Pneumonia (ANEMONE)
Status: COMPLETED
Conditions: Coronavirus Disease 2019
Interventions: DRUG: M5049|DRUG: M5049|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Left Ventricular Diastolic Dysfunction
Status: TERMINATED
Conditions: Hypertension, Pulmonary|Ventricular Dysfunction, Left
Interventions: DRUG: Riociguat (BAY63-2521)|DRUG: Riociguat (BAY63-2521)|DRUG: Riociguat (BAY63-2521)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1b/2 Study of Rogaratinib (BAY1163877) in Combination With Atezolizumab in Urothelial Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Urothelial Carcinoma
Interventions: DRUG: Rogaratinib (BAY1163877)|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SHCP in 4-H Using Teenagers as Teachers
Status: COMPLETED
Conditions: Nutrition Knowledge|Vegetable Preferences|Youth Engagement|Civic Responsibility
Interventions: BEHAVIORAL: Teenagers as cross-age SHCP teachers for younger youth
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Icaritin Soft Capsule Combined With Lenvatinib and TACE for the Treatment of Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: TACE（transcatheter arterial chemoembolization）|DRUG: lenvatinib|DRUG: Icaritin soft capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anatomical and Functional Outcome of PSG Vs BMG for Urethral Substitution in Long Segment Anterior Urethral Strictures
Status: RECRUITING
Conditions: Anterior Urethral Stricture, Male
Interventions: PROCEDURE: Penile skin graft substituttion urethroplasty|PROCEDURE: Buccal Mucosal Graft substitution urethroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial Comparing ABI-007 (Abraxane®, Nab®-Paclitaxel) to Taxotere in First Line Therapy of Patients With Stage IV Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: ABI-007|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0421, Docetaxel and Prednisone With or Without Atrasentan in Treating Patients With Stage IV Prostate Cancer and Bone Metastases That Did Not Respond to Previous Hormone Therapy
Status: COMPLETED
Conditions: Metastatic Cancer|Prostate Cancer
Interventions: DRUG: atrasentan hydrochloride|DRUG: docetaxel|DRUG: prednisone|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Artemisinin-based Combination Treatments in the Democratic Republic of the Congo
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: artesunate-amodiaquine|DRUG: artemether-lumefantrine|DRUG: Dihydroartemisinine-piperaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Luteinizing Hormone-Releasing Hormone Agonist Therapy and Iodine I 125 Implant in Treating Patients With Previously Untreated Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Adjuvant therapy|DRUG: Neoadjuvant therapy|RADIATION: Brachytherapy（iodine I 125）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Neuroimaging Effects of Cognitive Remediation Training
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Cognitive Remediation|BEHAVIORAL: Cognitive Behavioral Social Skills Training|OTHER: Retest in Health Controls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Enamel Caries in Orthodontic Patients
Status: COMPLETED
Conditions: Dental Caries
Interventions: PROCEDURE: Tooth Brushing HA|PROCEDURE: Tooth Brushing FL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of Low Carbohydrate Diet in Reducing Polypharmacy for Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Low carbohydrate diet|DIETARY_SUPPLEMENT: Calori restricted diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Liposomal Bupivacaine Versus Standard Bupivacaine Plus Dexamethasone in Quadriceps Sparing Femoral Nerve Block and Wound Infiltration for Total Knee Arthroplasty
Status: WITHDRAWN
Conditions: Osteoarthritis|Pain, Postoperative
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine plus dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mitigation of Radiation Pneumonitis, Fibrosis and Heart Toxicity With Nicorandil in Lung Cancer Patients
Status: UNKNOWN
Conditions: Radiation Pneumonitis
Interventions: DRUG: Nicorandil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of Quality of Life in Patients With Symptomatic Chemotherapy-induced Anaemia
Status: COMPLETED
Conditions: Anemia|Breast Cancer|Cancer|Colorectal Cancer|Lung Cancer|Ovarian Cancer|Prostate Cancer|Solid Tumors|Bladder Cancer|Endometrial Cancer|Renal Cancer|Pancreatic Cancer|Esophageal Cancer|Gastric Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Misoprostol Alone to Dilapan With Misoprostol and Comparing Buccal to Vaginal Misoprostol
Status: COMPLETED
Conditions: Second Trimester Abortions
Interventions: PROCEDURE: Misoprostol administered vaginally|PROCEDURE: Misoprostol administered buccally|PROCEDURE: Misoprostol administered vaginally with Dilapan|PROCEDURE: Misoprostol administered buccally with Dilapan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standardizing Right Hemicolectomy for Colon Cancer
Status: NOT_YET_RECRUITING
Conditions: Colonic Carcinoma|Laparoscopic Right Hemicolectomy|Standardisation|Training|Delphi Study|Implementation|Consolidation|Assessment
Interventions: PROCEDURE: Implementation standardised laparoscopic right hemicolectomy with proctoring|PROCEDURE: Implementation standardised laparoscopic right hemicolectomy without proctoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Zonisamide and Carbamazepine as an Initial Monotherapy: Efficacy and Safety Evaluation
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: zonisamide|DRUG: carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Contribution, Prognosis and Physiopathological Aspects in Arrhythmogenic Cardiomyopathy. (ACORE)
Status: NOT_YET_RECRUITING
Conditions: Arrhythmogenic Cardiomyopathy
Interventions: BIOLOGICAL: Prospective|OTHER: Retrospective
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial Of The Effectiveness Of The Product Cloratadd D (Loratadine + Pseudoephedrine Sulfate) Produced By The Laboratory EMS S/A, Compared To The Drug Claritin D Produced By Schering-Plough S/A, In Patients With Allergic Rhinitis
Status: WITHDRAWN
Conditions: Allergic Rhinitis
Interventions: DRUG: Loratadine + Pseudoephedrine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAtheter-Based Ablation of Atrial Fibrillation Compared to Conventional Treatment in Patients With Heart Failure With Preserved Ejection Fraction
Status: RECRUITING
Conditions: Atrial Fibrillation|Heart Failure With Preserved Ejection Fraction|Heart Failure With Mildly Reduced Ejection Fraction
Interventions: DEVICE: CE-marked Catheter Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiological Assessments During Non Operative Treatment on the Chest Wall Deformities
Status: RECRUITING
Conditions: Pectus Excavatum|Pectus Carinatum
Interventions: DEVICE: Vacuum Bell|DEVICE: Dynamic Compression System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Y101D, a PD-L1/TGF-β Bispecific Antibody, in Patients With Metastatic or Locally Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic or Locally Advanced Solid Tumors
Interventions: DRUG: Cohort 1 of Y101D|DRUG: Cohort 2 of Y101D|DRUG: Cohort 3 of Y101D|DRUG: Cohort 4 of Y101D|DRUG: Cohort 5 of Y101D
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Depression in Methadone Maintenance Patients Receiving Hepatitis C Treatment - 1
Status: COMPLETED
Conditions: Depressive Disorder, Major|Hepatitis C
Interventions: BEHAVIORAL: Cognitive behavioral treatment for depression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: System Interventions to Achieve Early and Equitable Transplants (STEPS) Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: BEHAVIORAL: STEPS Health System Outreach intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Monitoring Metered Dose Inhalation (MDI) Volume and Timing With a Respimetrix Device in Obstructive Lung Disease.
Status: COMPLETED
Conditions: Asthma|Copd
Interventions: DEVICE: Respimetrix
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy, Safety and CNS Exposure of G-202 (Mipsagargin) in Patients With Recurrent or Progressive Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: G-202
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Injection in Cancer Survivors
Status: COMPLETED
Conditions: Cardiomyopathy Due to Anthracyclines
Interventions: BIOLOGICAL: Allo-MSCs|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Tumor Metabolism by Isotopic Tagging in Patients With High-grade Glioma (CARBONOMIC)
Status: TERMINATED
Conditions: High-grade Glioma
Interventions: DRUG: C13 N15 Valine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Masseter and Anterior Temporalis Muscles Activity After Locating Centric Relation
Status: COMPLETED
Conditions: Centric Occlusion - Centric Relation Discrepancy (Disorder)
Interventions: DEVICE: Leaf Gauge|DEVICE: Lucia Jig|DEVICE: Kois Deprogrammer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Multicenter Assessment of LBR-101 in High Frequency Episodic Migraine
Status: COMPLETED
Conditions: Episodic Migraine Headache
Interventions: DRUG: LBR-101 High Dose|DRUG: LBR-101 Low Dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endodontic Treatment of Primary Teeth Using Mineral Trioxide Aggregate Paste
Status: COMPLETED
Conditions: Teeth, Endodontically-Treated
Interventions: DRUG: Endodontic treatment using Vitapex|DRUG: Endodontic treatment using MTA paste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TMLI and Alemtuzumab for Treatment of Sickle Cell Disease
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: DRUG: Alemtuzumab|PROCEDURE: Hematopoietic Cell Transplantation|RADIATION: Intensity-Modulated Radiation Therapy|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Establishment of Pancreas Cancer and Cancer-associated Fibroblast Using EUS-guided Biopsy Samples
Status: RECRUITING
Conditions: Pancreas Adenocarcinoma
Interventions: OTHER: Pancreatic ductal adenocarcinoma organoids and cancer-associated fibroblasts establishment group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Docetaxel and Immunotherapy Prior to Prostatectomy for High-Risk Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Docetaxel|BIOLOGICAL: CG1940/CG8711
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Domiciliary Transcutaneous Electrical Stimulation in Obstructive Sleep Apnoea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Transcutaneous electrical stimulation|DEVICE: Continuous positive airway pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Hydrocortisone and Lidocaine Treatment of Grade I and II Hemorrhoids
Status: COMPLETED
Conditions: Hemorrhoids
Interventions: DRUG: Hydrocortisone acetate and lidocaine hydrochloride|DRUG: Placebo control|DRUG: Hydrocortisone acetate|DRUG: Lidocaine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploration of Knee Injuries Using 3 Tesla and 7 Tesla Magnetic Resonance Imaging at the University Hospital of Poitiers
Status: WITHDRAWN
Conditions: Traumatic Knee Injury|Knee
Interventions: OTHER: 7 Tesla MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: T-cells Expressing an Anti-SLAMF7 CAR for Treating Multiple Myeloma
Status: COMPLETED
Conditions: Myeloma-Multiple|Myeloma, Plasma-Cell
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Rimiducid|BIOLOGICAL: Anti-Signaling lymphocytic activation molecule F7 (SLAMF7) chimeric antigen receptor (CAR) T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outgoing Lung Team - a Cross-sectorial Intervention in Patients With COPD
Status: COMPLETED
Conditions: COPD|COPD Exacerbation
Interventions: OTHER: Affiliation with the outgoing lung team
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Safety of Cataract Removal by Phacoemulsification Surgery in Patients Under Anti-aggregant and Coumadin Treatment
Status: UNKNOWN
Conditions: Efficacy|Complications
Interventions: PROCEDURE: cataract surgery with phacoemulsification
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Prospective Study Evaluation of the Efficacy and Safety of Noninvasive Neuromodulation of TMS in Subjects With Catatonia
Status: RECRUITING
Conditions: Catatonia|Schizophrenia|Schizo Affective Disorder|Bipolar Affective Disorder
Interventions: DIAGNOSTIC_TEST: rTMS|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Stable Carbon And Nitrogen Isotopes to Improve Dietary Assessment for Cardiovascular Disease
Status: UNKNOWN
Conditions: Healthy Adults
Interventions: DIETARY_SUPPLEMENT: one 24 hr cycle of meals at a 2000 kcal level|DIETARY_SUPPLEMENT: one 24 hr cycle of meals at a 2000 kcal level + one serving sugar sweetened beverage|DIETARY_SUPPLEMENT: one 24 hr cycle of meals at a 2000 kcal level + two servings sugar sweetened beverage|DIETARY_SUPPLEMENT: one 24 hr cycle of meals at a 2000 kcal level + three serving sugar sweetened beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Standard vs High Prophylactic Doses or Anticoagulation in Patients With High Risk of Thrombosis Admitted With COVID-19 Pneumonia (PROTHROMCOVID)
Status: COMPLETED
Conditions: Covid19|Thrombosis
Interventions: DRUG: Tinzaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Levonorgestrel Intrauterine System Effects on Hemoglobin and Serum Ferritin Among Anemic Women in Kenya
Status: RECRUITING
Conditions: Anemia
Interventions: DEVICE: LNG IUS|DRUG: COCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy, Safety, and Pharmacokinetics Study of JNJ-56136379 in Participants With Chronic Hepatitis B Virus Infection
Status: COMPLETED
Conditions: Hepatitis B
Interventions: DRUG: JNJ-56136379|DRUG: Placebo|DRUG: NA (ETV or TDF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of Diltiazem, a Moderate CYP3A4/A5 Inhibitor, on the Pharmacokinetics and Pharmacodynamics of E5555 and Its Metabolites in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: E5555 100 mg and diltiazem|DRUG: E5555 300 mg and diltiazem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Intravenous Azacitidine Alone in Patients With Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gamma-Secretase Inhibitor RO4929097 and Gemcitabine Hydrochloride in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Adenocarcinoma of the Pancreas|Recurrent Pancreatic Cancer|Stage III Pancreatic Cancer|Stage IV Pancreatic Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: gamma-secretase/Notch signalling pathway inhibitor RO4929097|DRUG: gemcitabine hydrochloride|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amniotic Membrane Allograft Application in the Management of Venous Leg Ulcerations
Status: TERMINATED
Conditions: Varicose Ulcer|Venous Insufficiency
Interventions: BIOLOGICAL: AmnioExCel dressing and compression therapy|PROCEDURE: SOC alginate dressing and compression therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Task Sharing for the Care of Severe Mental Disorders in a Low-income Country
Status: COMPLETED
Conditions: Schizophrenia|Bipolar Disorder|Major Depressive Disorder|Schizoaffective Disorder
Interventions: BEHAVIORAL: Integrated mental health in primary care|BEHAVIORAL: Psychiatric nurse-led specialist care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Splinted and Unsplinted OT Bridge Systems in Screw Retained Implant Restoration
Status: UNKNOWN
Conditions: Evaluate the Immediate Loading Implants in All on 4 Cases Using Conversion Denture and OT Bridge System
Interventions: PROCEDURE: Splinting of OT Bridge system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Treatment of Patients With Soft Tissue Sarcoma Including Preoperative Stereotactic Radiation Therapy and Postoperative Conformal Radiation Therapy
Status: RECRUITING
Conditions: Soft Tissue Sarcoma Adult
Interventions: RADIATION: Preoperative stereotactic radiation therapy in hypofractionation mode|PROCEDURE: Surgery|RADIATION: Postoperative conformal radiation therapy in normofractionation mode
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of GLWL-01 in Patients With Prader-Willi Syndrome
Status: COMPLETED
Conditions: Prader-Willi Syndrome
Interventions: DRUG: GLWL-01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Measuring Automated Behavioral Observations & Vocal Expressions (ABOVE)
Status: ACTIVE_NOT_RECRUITING
Conditions: OCD|Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Provocation OC task (Provoc)|BEHAVIORAL: Trier Social Stress Test (TSST)|BEHAVIORAL: Exposure provocation task
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Amobarbital Sodium Combined With Low-dose Propofol on Hemodynamics During Induction and Perioperative Adverse Reactions
Status: NOT_YET_RECRUITING
Conditions: Amobarbital Sodium|Hemodynamics Instability
Interventions: DRUG: Amobarbital|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab in Treating Patients With Stage IV Metastatic or Recurrent Inflammatory Breast Cancer or Triple-Negative Breast Cancer Who Have Achieved Clinical Response or Stable Disease to Prior Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Edema|Erythema|Estrogen Receptor Negative|HER2/Neu Negative|Peau d'Orange|Progesterone Receptor Negative|Recurrent Inflammatory Breast Carcinoma|Stage IV Inflammatory Breast Carcinoma|Triple-Negative Breast Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osteotome Sinus Floor Elevation With or Without Grafting
Status: COMPLETED
Conditions: Dental Implants|Sinus Floor Augmentation|Bone Remodeling
Interventions: DEVICE: SLA dental implants|PROCEDURE: Osteotome sinus floor elevation|PROCEDURE: Bone grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Trial of Ublituximab and TGR-1202 in Combination or as Single Agents in Subjects Currently Receiving Treatment on Ublituximab and/or TGR-1202 Trials
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia|Non Hodgkin Lymphoma
Interventions: DRUG: TGR-1202|DRUG: TGR-1202 + Ublituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Gas Analysis and Buffering In Cardiac Arrest
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: DRUG: Sodium bicarbonate|DRUG: Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enfortumab Vedotin and Pembrolizumab vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Urothelial Cancer
Interventions: DRUG: Enfortumab vedotin|DRUG: Pembrolizumab|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Spinal Manipulation on Central Nervous System Activity Measured by Reflexive Calf Muscle Recruitment
Status: COMPLETED
Conditions: Subluxation of Joint of Lumbar Spine
Interventions: PROCEDURE: Spinal Manipulation|PROCEDURE: Max Voluntary Isometric Contraction|PROCEDURE: SM+MVIC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Therapeutic Study to Evaluate the Safety and Efficacy of DW-MSC in COVID-19 Patients
Status: COMPLETED
Conditions: Covid19|Corona Virus Infection|SAR
Interventions: DRUG: allogeneic mesenchymal stem cell|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Syndrome and Degenerate Meniscus Tears
Status: COMPLETED
Conditions: Metabolic Syndrome|Meniscus; Degeneration
Interventions: DIETARY_SUPPLEMENT: Calorie restricted diet and exercise intervention|PROCEDURE: libitum diet and waiting list control group|PROCEDURE: Early arthroscopic partial menisectomy group|PROCEDURE: delayed APM group recruit participants with symptoms lasting for more than 6 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Vitamin D on Diabetic Kidney Disease in African Americans
Status: COMPLETED
Conditions: Diabetic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Artery Pressure Reduction With ENTresto (Sacubitril/Valsartan)
Status: TERMINATED
Conditions: Congestive Heart Failure
Interventions: DEVICE: Implantable Hemodynamic Monitor|DRUG: Angiotensin-Converting Enzyme Inhibitor|DRUG: Angiotensin II Type 1 Receptor Blocker|DRUG: sacubitril/valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Collection of Biospecimen & Clinical Information in Patients w/ Gastrointestinal Cancers
Status: WITHDRAWN
Conditions: Gastrointestinal Neoplasms|Gynecologic Cancers|Gynecologic Cancers Cervical Cancer|Gastric (Stomach) Cancer|Gastro-Esophageal(GE) Junction Cancer|Gastrointenstinal Stromal Tumor (GIST)|Colon/Rectal Cancer|Colon/Rectal Cancer Colon Cancer|Colon/Rectal Cancer Rectal Cancer|Colon/Rectal Cancer Anal Cancer|Anal Cancer|Hepatobiliary Cancers|Hepatobiliary Cancers Liver|Pancreatic Cancer
Interventions: PROCEDURE: Blood Draw|PROCEDURE: Frozen Tumor Specimens
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study on Left Atrial Function of Atrial Fibrillation After Radiofrequency Ablation With Statin Therapy
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: atorvastatin group|DRUG: non-atorvastatin group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Treatment With Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile Men With Idiopathic Oligoasthenoteratospermia
Status: RECRUITING
Conditions: Infertility Unexplained|Oligospermia
Interventions: DRUG: co enzyme Q10 , L- Carnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Laser Doppler Flowmetry as a Diagnostic Tool in Assessing Revascularization of Traumatised Teeth
Status: UNKNOWN
Conditions: Trauma|Diagnosis Dual
Interventions: DIAGNOSTIC_TEST: Measurement of pulpal blood flow of traumatised tooth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Comparison of Renal Perfusion in Thoracoabdominal Aortic Aneurysm (TAAA) Repair
Status: COMPLETED
Conditions: Renal Failure
Interventions: PROCEDURE: Cold blood renal perfusion|PROCEDURE: Cold crystalloid renal perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT