pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Physical Activity on Prescription (PAP) as a Health-enhancing Intervention in People With Disabilities
Status: RECRUITING
Conditions: Physical Inactivity|Cerebral Palsy|Autism|Autism Spectrum Disorder|Intellectual Disability|Disability Physical|Sedentary Behavior
Interventions: BEHAVIORAL: Physical activity on prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Controlled Trial of Serotonin Reuptake Inhibitors Added to Stimulant Medication in Youth With Severe Mood Dysregulation
Status: COMPLETED
Conditions: Mood Disorder|Mental Disorder Diagnosed in Childhood|Attention Deficit and Disruptive Behavior Disorder|Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Add-on citalopram following optimized methylphenidate|DRUG: Add-on placebo following optimized methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Different Low-level Laser Therapies to Treat Neck Pain in Air Force Pilots and Flight Crew
Status: RECRUITING
Conditions: Neck Pain
Interventions: PROCEDURE: Group 1 -- using Pinnacle Series Laser Device|PROCEDURE: Group 2 -- using Pinnacle Series Laser Device|PROCEDURE: Group 3 -- using Phoenix Thera-Lase Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of the Mechanical Peripheral Stimulation for Parkinson's Disease Rehabilitation
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DEVICE: Mechanical Peripheral Stimulation (GONDOLA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of PIR With and Without Dry Needling on Heel Pain
Status: RECRUITING
Conditions: Heel Pain Syndrome
Interventions: OTHER: MET PIR with Dry Needling|OTHER: MET PIR without Dry Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Finding Safety Study Evaluating Remimazolam (CNS 7056) in Patients Undergoing Diagnostic Upper GI Endoscopy
Status: COMPLETED
Conditions: Procedural Sedation|Endoscopy
Interventions: DRUG: CNS 7056|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Eye Movement Recording as an Early Differential Diagnostic Tool for Alzheimer/Depression
Status: UNKNOWN
Conditions: Alzheimer Disease|Depression
Interventions: OTHER: Eye movements will be recorded using video-oculography techniques based on both the corneal reflection principle and an infra-red light beam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multimodal Investigation of the Neuroprotective Effects of Resveratrol (MINER)
Status: UNKNOWN
Conditions: Gulf War Illness
Interventions: DRUG: Resveratrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Psyllium (Plantago Ovata) on Digestive Disorders in Familial Amyloidosis
Status: WITHDRAWN
Conditions: Familial Amyloidosis
Interventions: DIETARY_SUPPLEMENT: Psyllium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Efficacy and Safety of VTAMA (Tapinarof) Cream, 1% in Intertriginous Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: VTAMA® (tapinarof) Cream 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STEREO-POSTOP 01 (PostOperative Hypofractionated Stereotactic Body Radiotherapy ) - GORTEC 2017-03
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Neoplasms
Interventions: RADIATION: postoperative hypofractionated stereotactic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PCOM2 - The Physician Communication Intervention, Version 2.0
Status: RECRUITING
Conditions: HPV Infection|Preventive Health Services
Interventions: BEHAVIORAL: Physician Communication 2 Virtual (PCOM2-virtual)|BEHAVIORAL: Physician Communication Standard (PCOM-standard)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Self-Management Of Asthma By Forced Oscillation Technique
Status: RECRUITING
Conditions: Asthma
Interventions: OTHER: Optimized self-management of asthma|OTHER: Conventional self-management of asthma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Collateral Ventilation Effects on Response to AeriSeal System Treatment in Upper Lobe Predominant Emphysema
Status: TERMINATED
Conditions: Pulmonary Emphysema
Interventions: DEVICE: Emphysematous Lung Sealant|DEVICE: Emphysematous Lung Sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of Oral PTH (1-34) Formulations in Healthy Subjects
Status: COMPLETED
Conditions: Drug Safety and Bioavailability
Interventions: DRUG: Teriparatide|DRUG: Oral PTH (1-34)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Saline Against Lactated Ringers or Plasmalyte in the Emergency Department
Status: COMPLETED
Conditions: Critical Illness|Acute Kidney Injury
Interventions: OTHER: 0.9% Saline|OTHER: Physiologically-balanced isotonic crystalloid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROphylactic Manual RotatIon in the Second stagE of Labor
Status: TERMINATED
Conditions: Labor Complication|Pregnancy Related
Interventions: PROCEDURE: Prophylactic manual rotation|PROCEDURE: Sham rotation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: ANI and SPI Guided Intraoperative Analgesia
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Sufentanil SPI analgesia|DRUG: Sufentanil ANI analgesia|DRUG: Sufentanil anesthesiologist analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Learning From Errors During Simulation-based Ultrasound Training
Status: COMPLETED
Conditions: Simulation-based Ultrasound Training, Error-management Training, Training With Errors, Skills Transfer
Interventions: PROCEDURE: Error-management training vs error-avoidance training. Defined by training instructions.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Comparing the Effects of Three Different Dressings on the Cutaneous Response of Sacral Skin
Status: COMPLETED
Conditions: Pressure Ulcer Prevention
Interventions: OTHER: No dressing|OTHER: Mepilex® Border Sacrum|OTHER: ALLEVYN Life Sacrum|OTHER: Optifoam® Gentle Sacrum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: AEGR-733 and Atorvastatin 20 mg vs. Monotherapy in Moderate Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Atorvastatin 20 mg|DRUG: AEGR-733 5 mg|DRUG: AEGR-733 10 mg|DRUG: Placebo|DRUG: AEGR-733 5 mg + atorvastatin 20 mg|DRUG: AEGR-733 10 mg + atorvastatin 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Conventional and Low-dose Platinum Gemcitabine Combined With Cindilimab With Delayed Administration in First-line Treatment of Advanced Squamous Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Cisplatin / Carboplatin，Gemcitabine，Cindilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cetirizine on Bronchoconstriction
Status: COMPLETED
Conditions: Allergic Rhinitis|Asthma
Interventions: DRUG: Cetirizine Hydrochloride 1 MG/ML|DRUG: Placebo - Concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of NSAID vs. Steroid-NSAID Combo Post-Selective Laser Trabeculoplasty: Phase 4, Single-Center RCT
Status: NOT_YET_RECRUITING
Conditions: Open Angle Glaucoma|Ocular Hypertension|Postoperative Inflammation
Interventions: DRUG: Ketorolac 0.5% Eye Drops|DRUG: Ketorolac 0.5% and Fluorometholone 0.1% Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Dexmedetomidine for Post-laparoscopic Appendicectomy Pain Management in Children
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: Bupivacaine|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Bilateral Rectus Sheath and Oblique Subcostal Transversus Abdominis Plane Block on Mechanical Power
Status: COMPLETED
Conditions: Mechanical Power
Interventions: PROCEDURE: Bilateral Oblique Subcostal Transversus Abdominis Plane Block (OSTAP) will be performed.|PROCEDURE: Bilateral Rectus Sheath Block (RSB) will be performed.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy and Safety of Gemcitabine in Combination With Docetaxel to Treat Pancreatic or Biliary Cancer
Status: COMPLETED
Conditions: Pancreatic Neoplasms|Biliary Tract Neoplasms
Interventions: DRUG: Docetaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Single and Multiple Doses of ISIS 353512 in Healthy Volunteers
Status: COMPLETED
Conditions: Inflammatory Diseases
Interventions: DRUG: ISIS 353512|DRUG: ISIS 353512|DRUG: ISIS 353512|DRUG: ISIS 353512|DRUG: ISIS 353512|DRUG: ISIS 353512|DRUG: ISIS 353512|DRUG: ISIS 353512|DRUG: ISIS 353512|DRUG: ISIS 353512|DRUG: ISIS 353512|DRUG: ISIS 353512|DRUG: ISIS 353512|DRUG: ISIS 353512|DRUG: ISIS 353512|DRUG: ISIS 353512
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Screening Women With Prior HPV for Anal Neoplasia
Status: RECRUITING
Conditions: HPV-related Lower Genital Tract Neoplasias|HPV-related Anal Neoplasias|Early Stage Lower Genital Tract Cancers
Interventions: DIAGNOSTIC_TEST: Diagnostic tests for anal cancer screening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: An Epidemiological Study to Assess Iron Overload Using MRI in Patients With Transfusional Siderosis (TIMES Study)
Status: COMPLETED
Conditions: Thalassemia, Non-transfusional-dependent Thalassemia (NTDT), Myeloplastic Dysplasia (MDS), Other Anemia
Interventions: DEVICE: MRI scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dose Escalation Study of Intravitreal 4D-110 in Patients With Choroideremia
Status: ACTIVE_NOT_RECRUITING
Conditions: Choroideremia
Interventions: BIOLOGICAL: 4D-110
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systane Ultra Versus Maxidex Versus Saline
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: Systane Ultra|DRUG: Saline solution|DRUG: Maxidex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiomic Diagnostics in Youth With Psychosis
Status: RECRUITING
Conditions: Psychosis
Interventions: GENETIC: Genetic: Genomic sequencing and molecular diagnostic results, if any.|DIAGNOSTIC_TEST: Phage display ImmunoPrecipiation Sequencing (PhIP-Seq)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study to Evaluated Which Number of Passes of EUS-FNB is Better for Culturing Primary Cells of PDAC
Status: UNKNOWN
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: PROCEDURE: different number of passes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Characterization of the Metabolic Fate of an Oral Arginine Form
Status: COMPLETED
Conditions: Overweight|Hypertriglyceridemic Waist
Interventions: DIETARY_SUPPLEMENT: A form Arginine|DIETARY_SUPPLEMENT: B form Arginine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Mechanical Bowel Preparation and Oral Antibiotics Before Rectal Cancer Surgery
Status: COMPLETED
Conditions: Rectal Cancer Surgery
Interventions: DRUG: Sennosides colonic preparation|DRUG: Oral Gentamycin|DRUG: Oral Ornidazole|DRUG: Oral Placebo Gentamycin|DRUG: Oral Placebo Ornidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Trial Comparing Sitagliptin to Placebo in Closed Loop
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Placebo and Insulin monotherapy via CL|DRUG: Sitagliptin and insulin/novolog via CL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple, Rising Oral Doses of BI 11634 Oral Solution in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 11634|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Experimental Human Rhinovirus Infection
Status: COMPLETED
Conditions: Common Cold
Interventions: OTHER: placebo|OTHER: Human Rhinovirus strain 16 (HRV-16)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Investigate the Blood Concentration of Liraglutide as Well as the Effects on Glucose and Insulin After 21 Days of Daily Subcutaneous Injections of Liraglutide or Placebo
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: liraglutide|DRUG: placebo|DRUG: liraglutide|DRUG: placebo|DRUG: liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetics and Pharmacodynamics Study Under Fasting and Fed Conditions With Paliperidone Extended-release and Immediate-release Formulations
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: ER Paliperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: General Exercises With and Without TA Contraction in Patients With Nonspecific Acute LBP
Status: RECRUITING
Conditions: Low Back Pain
Interventions: OTHER: General exercises|OTHER: General exercises with tranversus abdmoinis contraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Cardiometabolic Risk and Promoting Functional Health in Older Adults With Obesity and Prediabetes
Status: COMPLETED
Conditions: Obesity|PreDiabetes|Aging
Interventions: BEHAVIORAL: DPP Intensive: 30-minute calls|BEHAVIORAL: DPP Support: 15-minute calls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Regimen Optimization Trial of PfSPZ Vaccine in Equatorial Guinea
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: PfSPZ Vaccine|OTHER: Normal saline|BIOLOGICAL: PfSPZ Challenge (for CHMI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Role and Interactions of Adenosine, Receptors, Methionine Cycle Nutritional, Metabolic and Genetic Determinants in the Onset of Atrial Fibrillation in Normal Heart
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: OTHER: Quantification assay of adenosine and methionine cycle metabolites|GENETIC: Polymorphism analysis of genes related to adenosine metabolism and methionine cycle|OTHER: Quantitative and qualitative nutritional evaluation|BIOLOGICAL: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Extended Duration Nicotine Replacement Therapy and Bupropion in Smokers With Schizophrenia
Status: TERMINATED
Conditions: Nicotine Dependence|Schizophrenia
Interventions: DRUG: NRT|DRUG: Bupropion SR 150mg bid|OTHER: Relapse Prevention-Oriented Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interaction of the Cognitive and Sensory-cognitive Tasks With Postural Stability in Individuals With Stability Disorders
Status: UNKNOWN
Conditions: Cerebellar Ataxia|Cerebellar Diseases
Interventions: DIAGNOSTIC_TEST: Stabilometry|DIAGNOSTIC_TEST: Stroop test|DIAGNOSTIC_TEST: Backward counting test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Motivational Interviewing to Enhance Advance Care Planning for Older Adults and Caregivers After Emergency Visits
Status: RECRUITING
Conditions: Older Adults|Advance Care Planning|Advance Directives|Family Members
Interventions: OTHER: MI-based ACP intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Optimization of Remotely Delivered Physical Activity Intervention for Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Cancer Female|Physical Activity
Interventions: BEHAVIORAL: Core|BEHAVIORAL: Support Calls|BEHAVIORAL: App+|BEHAVIORAL: Online gym|BEHAVIORAL: App notifications|BEHAVIORAL: Buddy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Visco-Circumferential-Suture-Trabeculotomy Versus Rigid Probe Viscotrabeculotomy in Primary Open Angle Glaucoma
Status: NOT_YET_RECRUITING
Conditions: Primary Open Angle Glaucoma
Interventions: PROCEDURE: Visco-Circumferential-Suture-Trabeculotomy in Primary Open Angle Glaucoma.|PROCEDURE: Rigid probe Viscotrabeculotomy in Primary Open Angle Glaucoma.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Safety of Subcutaneous Immunotherapy With gpASIT+™ in Patients With Grass Pollen-induced Allergic Rhinoconjunctivitis
Status: UNKNOWN
Conditions: Hay Fever
Interventions: BIOLOGICAL: Placebo solution|BIOLOGICAL: gpASIT+TM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intelligent Diagnosis and Treatment System for Pelvic Floor Dysfunction in Elderly Women
Status: RECRUITING
Conditions: Pelvic Organ Prolapse|Urinary Incontinence|Diagnosis
Interventions: PROCEDURE: Personalized pelvic floor rehabilitation program generated by the intelligent diagnosis and treatment system.|PROCEDURE: Standard pelvic floor muscle training(PFMT) program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resolution of Comorbidities, Safety and Efficacy of Greater Curvature Plication in Obese Patients.
Status: UNKNOWN
Conditions: Obesity
Interventions: PROCEDURE: Laparoscopic Greater Curvature Plication
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess Safety and Efficacy of Sovateltide in Hypoxic-ischemic Encephalopathy
Status: RECRUITING
Conditions: Hypoxic-Ischemic Encephalopathy|Neonatal Asphyxia|Neonatal Encephalopathy
Interventions: DRUG: Normal Saline along with standard treatment|DRUG: Sovateltide along with standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The INtegrilin Plus STenting to Avoid Myocardial Necrosis Trial (INSTANT)
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DRUG: Eptifibatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gene Expression in Patients With Metastatic Prostate Cancer Receiving CYP-17 Inhibition Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Hormone-Resistant Prostate Cancer|Metastatic Prostate Carcinoma|Prostate Adenocarcinoma|Recurrent Prostate Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rasburicase Treatment for Chemotherapy or Malignancy-Induced Hyperuricemia in Asthma/Allergy Patients
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Tumor Lysis Syndrome|Hyperuricemia
Interventions: DRUG: Rasburicase
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tretinoin and Arsenic Trioxide in Treating Patients With Untreated Acute Promyelocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Promyelocytic Leukemia With t(15;17)(q24.1;q21.2); PML-RARA
Interventions: DRUG: Arsenic Trioxide|DRUG: Cytarabine|DRUG: Dexamethasone|DRUG: Idarubicin|OTHER: Laboratory Biomarker Analysis|DRUG: Mitoxantrone Hydrochloride|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Tretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Typhoid Fever: Combined vs. Single Antibiotic Therapy
Status: UNKNOWN
Conditions: Typhoid Fever
Interventions: DRUG: ceftriaxone|DRUG: ceftriaxone and azithromycin|DRUG: azithromycin|DRUG: azithromycin and cefixime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mid-luteal Phase Synchronization of Ovarian Folliculogenesis in Women
Status: COMPLETED
Conditions: Ovarian Follicle
Interventions: DRUG: Marvelon|DRUG: Nuvaring|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Injection Assistance Device Versus Manual Injections for Delivery of Dermal Fillers
Status: UNKNOWN
Conditions: Correction of Nasolabial Folds
Interventions: PROCEDURE: Subdermal Injection|DEVICE: Artiste Assisted Injection System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual-reality Exercises for Alleviating Attention Deficits in Patients With Acquired Brain Injury
Status: RECRUITING
Conditions: Stroke|Attention Disorder
Interventions: OTHER: Immersive virtual reality gamified cognitive activities|OTHER: Double neuropsychological standard activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prostate Imaging Using MRI +/- Contrast Enhancement
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: Multiparametric MRI +/- prostate biopsy|DIAGNOSTIC_TEST: Biparametric MRI +/- prostate biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of COVID-19 Vaccination in Patientstreated With Anti-CD20 for Follicular Lymphoma or Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Follicular Lymphoma|Mantle Cell Lymphoma
Interventions: BIOLOGICAL: Determination of COVID-19 vacciantion efficacy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Computer Training and Transcranial Direct Current Stimulation for Cognition in HIV
Status: COMPLETED
Conditions: HIV-related Mild Neurocognitive Disorder
Interventions: PROCEDURE: Transcranial Direct Current Stimulation (tDCS)|BEHAVIORAL: Computer-based Cognitive Training|BEHAVIORAL: Watching Educational Videos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A New Strategy for Preoperative Drainage of Resectable Pancreatic Head Cancer Combined Severe Obstructive Jaundice
Status: RECRUITING
Conditions: Pancreatic Cancer|Obstructive Jaundice
Interventions: PROCEDURE: Modified strategy|PROCEDURE: Traditional strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Procalcitonin Guided Antibiotic Use in Acute Respiratory Tract Infections (PARTI)-Study
Status: COMPLETED
Conditions: Respiratory Tract Infections
Interventions: PROCEDURE: Procalcitonin guided antibiotic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Intratumorally Administered Stimulator of Interferon Genes (STING) Agonist E7766 in Participants With Advanced Solid Tumors or Lymphomas - INSTAL-101
Status: TERMINATED
Conditions: Lymphoma|Advanced Solid Tumors
Interventions: DRUG: E7766
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Resistance Exercise on Blood Glucose in Post-menopausal Women With Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: High repetition (HI)|BEHAVIORAL: Moderate repetition (MOD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD
Status: RECRUITING
Conditions: Attention-Deficit/Hyperactivity Disorder
Interventions: DRUG: 100mg SPN-812|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Protective Effects of Two Cardioplegic Solutions, on Cardiac Metabolism, as Assessed Using Microdialysis
Status: COMPLETED
Conditions: Coronary Artery Stenosis
Interventions: DRUG: St Thomas|DRUG: Custodiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effects of Ghrelin Administration on Motivation
Status: ENROLLING_BY_INVITATION
Conditions: Major Depressive Disorder
Interventions: DRUG: Ghrelin|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Intranasal Oxytocin on Headache in Chronic Daily Headache
Status: COMPLETED
Conditions: Chronic Daily Headache
Interventions: DRUG: Syntocinon|DRUG: Sterile water|DRUG: Syntocinon|DRUG: Sterile water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combining Pregabalin (LYRICA®) With Lofexidine (LUCEMYRATM) to Treat OPIOID Withdrawal
Status: COMPLETED
Conditions: Opioid Withdrawal
Interventions: DRUG: Pregabalin 200 MG capsules|DRUG: Placebo oral tablet|DRUG: Lofexidine 0.18Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Sintilimab in Combination With IBI305 (Anti-VEGF Monoclonal Antibody) Compared to Sorafenib as the First-Line Treatment for Advanced Hepatocellular Carcinoma.
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sintilimab|DRUG: IBI305|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Evaluation of Glucose Profile Using Continuous Glucose Monitoring System in Glucose Intolerant Patients
Status: NOT_YET_RECRUITING
Conditions: Hyperglycaemia (Diabetic)|Bariatric Surgery Candidate
Interventions: DIETARY_SUPPLEMENT: carbohydrate supplement (Preload™)|PROCEDURE: 6 hours of preoperative fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: In-vivo Regulatory T Cell Enhancement With Cyclophosphamide and Sirolimus
Status: TERMINATED
Conditions: Graft Versus Host Disease
Interventions: DRUG: Cyclophosphamide and Sirolimus|DRUG: Low dose IL-2 with Cytoxan + Sirolimus|DRUG: Low dose IL-2, low dose Vidaza, cyclophosphamide & Sirolimus|DRUG: Cyclophosphamide and Sirolimus|DRUG: Low dose IL-2 with Cytoxan + Sirolimus|DRUG: Low dose IL-2, Vidaza, Cytoxan & Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Liquid Alpha1-Proteinase Inhibitor (Human) in Hospitalized Participants With Coronavirus Disease (COVID-19)
Status: TERMINATED
Conditions: COVID-19
Interventions: BIOLOGICAL: Liquid Alpha1-Proteinase Inhibitor (Human)|DRUG: Placebo|DRUG: Standard Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BM-MNCs and UC-MSCs Infusion for Type 2 Diabetes Mellitus Patients
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: BIOLOGICAL: BM-MNC and UC-MSC|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability and Clinical Activity of TD-1211 in Patients With Opioid-Induced Constipation
Status: COMPLETED
Conditions: Opioid-induced Constipation (OIC)
Interventions: DRUG: TD-1211|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperthermia and Olaparib in Treating Breast Cancer Patients With Chest Wall Recurrences
Status: UNKNOWN
Conditions: Metastatic Malignant Neoplasm in the Chest Wall|Recurrent Breast Carcinoma
Interventions: DRUG: Olaparib|PROCEDURE: Hyperthermia Treatment|OTHER: Questionnaire Administration|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Treatment of Hypercholesterolemia With Rosuvastatin and Ezetimibe
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Rosuvastatin and Ezetimibe morning or evening administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of EIT-guided Ventilation Strategy on ARDS Patients
Status: UNKNOWN
Conditions: ARDS|Pulmonary Perfusion
Interventions: PROCEDURE: EIT-guided PEEP setting|PROCEDURE: ARDS-net PEEP setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Asciminib as Initial Therapy for Patients With Chronic Myeloid Leukemia in Chronic Phase
Status: RECRUITING
Conditions: Chronic Myeloid Leukemia, Chronic Phase|Adult CML|Leukemia, Myeloid|Leukemia,Myeloid, Chronic
Interventions: DRUG: Asciminib|DRUG: Ascimininb + Nilotinib|DRUG: Asciminib + Imatinib|DRUG: Asciminib + Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lysergic Acid Diethylamide (LSD) in Palliative Care
Status: RECRUITING
Conditions: Palliative Care|Pain|Anxiety|Depression|Demoralization|Psychological Distress|Quality of Life|Caregiver Burden|Fear of Death|Existential Distress
Interventions: DRUG: Lysergic Acid Diethylamide Tartrate|DRUG: Lysergic Acid Diethylamide Tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study To Investigate The Hemodynamic Effects Of Single Dose Vardenafil In Subjects Receiving Maraviroc
Status: COMPLETED
Conditions: AIDS
Interventions: DRUG: Maraviroc|DRUG: Vardenafil|DRUG: Maraviroc|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Vibration on Bone Mineral Density in Women Who Have Weak Bones After Menopause
Status: COMPLETED
Conditions: Bone Density|Osteopenia|Osteoporosis|Post-Menopause
Interventions: DEVICE: Juvent 1000 Dynamic Motion Therapy (DMT) Platform|DEVICE: Juvent 1000 Dynamic Motion Therapy (DMT) Platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bridging the Gap: Using Video Art to Document the Human Face of Disease & Predict Quality of Life Assessments in Brain Tumor Patients
Status: COMPLETED
Conditions: Brain Tumors|Quality of Life|Animal Assisted Therapy
Interventions: BEHAVIORAL: Pet Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of HFNO on Spontaneous Ventilation in Obese Patients During Analgo-sedation for Vitrectomy
Status: UNKNOWN
Conditions: Sedation Complication|Obesity|Hypoxic Respiratory Failure|Airway Obstruction, Nasal|Respiratory Insufficiency|Apnea
Interventions: DEVICE: Device: low-flow nasal oxygenation (LFNO) 18<BMI<30 kg/m2|DEVICE: Device: low-flow nasal oxygenation (LFNO) 30≤BMI<35 kg/m2|DEVICE: Device: low-flow nasal oxygenation (LFNO) BMI≥35 kg/m2|DEVICE: Device: High-flow nasal oxygenation (HFNO) 18<BMI<30 kg/m2|DEVICE: Device: High-flow nasal oxygenation (HFNO) 30≤BMI<35 kg/m2|DEVICE: Device: High-flow nasal oxygenation (HFNO) BMI≥35 kg/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Pain and Inflammation After Surgery
Status: COMPLETED
Conditions: Knee Injuries
Interventions: DRUG: 1 Ketorolac intraarticular|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pantoprazole and Ranitidine in Dyspepsia
Status: COMPLETED
Conditions: Dyspepsia
Interventions: DRUG: Pantoprazole|DRUG: Ranitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dairy Product Matrices on Insulin Resistance in People With Overweight and Obesity and Prediabetes
Status: NOT_YET_RECRUITING
Conditions: PreDiabetes|Overweight and Obesity
Interventions: OTHER: 250 mL serving size, 3.25% fat content|OTHER: 175 g serving size, ≥2% fat content|OTHER: 50 g serving size, ≥28% fat content
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: ProbioKid as Prevention Among Kids With Frequent URTI
Status: COMPLETED
Conditions: Respiratory Tract Infections
Interventions: DIETARY_SUPPLEMENT: ProbioKid®|OTHER: Pragmatic comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Botulinum Toxin in the Treatment of Idiopathic Detrusor Overactivity
Status: UNKNOWN
Conditions: Overactive Detrusor
Interventions: DRUG: Botulinum toxin injected to bladder body|DRUG: Botulinum toxin injected into trigone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Clinical Trial to Investigate Effects of Vitamin K2 in COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: DIETARY_SUPPLEMENT: Vitamin K2 in the form of Menaquinone-7 (MK-7)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of ProSeal Laryngeal Mask Airway, LTS-D and I-gel in Mechanically Ventilated Patients
Status: COMPLETED
Conditions: Airway Morbidity
Interventions: DEVICE: ProSeal Laryngeal mask airway|DEVICE: Laryngeal Tube Suction- Disposable|DEVICE: i-gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Calcific Tendinitis of the Rotator Cuff
Status: COMPLETED
Conditions: Shoulder Pain|Tendonitis|Calcinosis|Shoulder Impingement Syndrome
Interventions: PROCEDURE: Barbotage|PROCEDURE: Corticosteroid injection|PROCEDURE: Lidocain injection (sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ASI-MV Solutions: A Tailored Program for Substance Abusers in Early Recovery
Status: COMPLETED
Conditions: Substance Abuse Treatment for Adults
Interventions: BEHAVIORAL: ASI-MV Solutions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effects of Kalydeco on Upper Airway and Paranasal Sinus Inflammation Measured by Nasal Lavage and on Symptoms
Status: COMPLETED
Conditions: Inflammatory Changes in Epithelial Lining Fluid Sampled Non-invasively by Nasal Lavage in CF Patients With G551D Receiving Kalydeco
Interventions: OTHER: nasal lavage (routine diagnostic procedure in our centre), assessment of symptoms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Imaging Study of 3D-CBCT Sialography and MRI Sialography in Non Tumor Salivary Diseases
Status: COMPLETED
Conditions: Non Tumor Salivary Gland Diseases of the Parotid Glands|Non Tumor Salivary Gland Diseases of the Submandibular Glands
Interventions: OTHER: Three-dimensional sialography CBCT and MRI sialography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Safety, Tolerability, and Pharmacokinetics of AZD9550 Following Single Ascending Dose Administration to Healthy Participants
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis
Interventions: DRUG: AZD9550|DRUG: AZD9550|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Culturally Optimized Messages for Latinos
Status: COMPLETED
Conditions: Diet, Healthy|Diet Habit|Obesity|Blood Pressure|Psychological
Interventions: BEHAVIORAL: Culturally tailored healthy eating advice|BEHAVIORAL: Standard healthy eating advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Measure the Impact of Antibiotics on Bacterial Flora in Adults With Acute Sinusitis
Status: TERMINATED
Conditions: Maxillary Sinusitis
Interventions: DRUG: Azithromycin|DRUG: Telithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effectiveness of Gamification Diabetes Education Program for Poorly Controlled Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Diabetic Patients, Gamification, Diabetic Education
Interventions: DEVICE: Gamification Diabetes Education Program (GDEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Textured Insoles and Exercise in Children With Joint Hypermobility
Status: RECRUITING
Conditions: Child, Only|Joint Laxity|Exercise|Textured Insoles
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Exercise+texture insoles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to a Novel Human Papillomavirus Vaccine in HIV Infected Children
Status: COMPLETED
Conditions: HIV Infections|Sexually Transmitted Diseases
Interventions: BIOLOGICAL: Quadrivalent human papillomavirus (types 6, 11, 16, 18) L1 virus-like particle (VLP) or Quadrivalent human papillomavirus vaccine (QHPV)|OTHER: Placebo/QHPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Pulsed Dye Laser on Photodynamic Therapy of Port-Wine Stains
Status: UNKNOWN
Conditions: Port-Wine Stain
Interventions: DEVICE: PDT treatment device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Taxotere Plus Weekly Navelbine and G-CSF: A Study in Stage IV Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasm
Interventions: DRUG: Docetaxel|DRUG: Vinorelbine|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of IABP Prior to Revascularization on Mortality of ACS Patients Complicated With Cardiogenic Shock
Status: COMPLETED
Conditions: Cardiogenic Shock
Interventions: DEVICE: Intra Aortic Balloon Pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperpolarized 129-Xenon Imaging in Adult Hematopoietic Cell Transplant Recipients With Pulmonary Impairment
Status: RECRUITING
Conditions: Pulmonary|Pneumonia|Hematopoietic System--Cancer
Interventions: DEVICE: 29-XeMRI imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of H3B-8800 (RVT-2001) in Participants With Lower Risk Myelodysplastic Syndromes
Status: TERMINATED
Conditions: Leukemia, Myeloid, Acute|Myelodysplastic Syndromes|Leukemia, Myelomonocytic, Chronic
Interventions: DRUG: H3B-8800 (RVT-2001)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pelvic Floor Exercises Versus Pilates on Urinary Incontinance in Chronic Obstructive Pulmonary Disease
Status: RECRUITING
Conditions: Urinary Incontinence
Interventions: OTHER: Pelvic floor on COPD patients|OTHER: Pilates exercises on COPD patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of QY101 Ointment in Subjects With Plaque Psoriasis
Status: RECRUITING
Conditions: Psoriasis
Interventions: DRUG: QY101Placebo/QY101 ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Foscarnet Sodium and Sodium Chloride Injection in Patients With Herpes Zoster
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: DRUG: Foscarnet Sodium|DRUG: Acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT