pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Radiofrequency Endoscopic Ablation With Ultrasound Guidance: a Non-surgical Treatment for Aldosterone-producing Adenomas
Status: COMPLETED
Conditions: Primary Hyperaldosteronism|Primary Hyperaldosteronism Due to Adrenal Adenoma
Interventions: PROCEDURE: Endoscopic ultrasound guided radiofrequency ablation|DEVICE: ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy Study of SHP465 in Children and Adolescents Aged 6-17 Years With Attention-Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: DRUG: SHP465|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ENDO-AID Assisted Tandem Colonoscopy RCT
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DIAGNOSTIC_TEST: ENDO-AID CADe assisted Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Proposal Evaluating Time-specific Relationships Between Variables of Pain, Stress, and Bloating in IBS Diarrhea and Constipation Symptoms Using a Palm Pilot
Status: COMPLETED
Conditions: IBS, Diarrhea Predominant|IBS, Constipation Predominant|IBS, Mixed Symptoms
Interventions: OTHER: palm pilot recording responses to questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NAC to Prevent Cisplatin-induced Hearing Loss
Status: COMPLETED
Conditions: Neuroectodermal Tumors, Primitive|Liver Neoplasms|Osteosarcoma|Other Childhood Cancers Using Cisplatin-based Regimens
Interventions: DRUG: N-Acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Exercises to Facilitate Recovery of Supination and Pronation for Distal Radius Fractures Managed With a Volar Plate
Status: ENROLLING_BY_INVITATION
Conditions: Distal Radius Fracture
Interventions: OTHER: Group 1 Elbow Flexed at 90 Degrees|OTHER: Group 2 Elbow Fully Flexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study Investigating the Effect of Food and Esomeprazole on the Single Oral Dose Pharmacokinetics of Alectinib (RO5424802) in Healthy Volunteers.
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Alectinib|DRUG: Esomeprazole|OTHER: High Fat and Calorie Meal|OTHER: Standard Meal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study Evaluating a Role for Maintenance Therapy in Patients With Biochemically Progressive Castration Sensitive Prostate Cancer on Intermittent Androgen Deprivation Therapy
Status: RECRUITING
Conditions: Castration Sensitive Prostate Cancer
Interventions: DRUG: Metformin|DRUG: Turmeric
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Mosapride Citrate on Gastrointestinal Motility After Gastrectomy: Prospective, Double Blind Placebo-controlled Study
Status: UNKNOWN
Conditions: Stomach Cancer
Interventions: DRUG: Mosapride citrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: POSTOPERATIVE OPIOID-SPARING EFFECT OF INTRAOPERATIVE PAIN MONITORING USING THE ANALGESIA NOCICEPTIVE INDEX (ANI) DURING IDIOPATHIC SCOLIOSIS CORRECTION IN CHILDREN.
Status: UNKNOWN
Conditions: Scoliosis Idiopathic
Interventions: DEVICE: THE ANALGESIA NOCICEPTIVE INDEX (ANI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Camel Milk With Probiotic on Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Camel milk containing Bifidobacterium animalis A6|DIETARY_SUPPLEMENT: Camel milk|DIETARY_SUPPLEMENT: Bifidobacterium animalis A6|DIETARY_SUPPLEMENT: Cow milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Single Arm, Multicenter, Phase II Trial of RAD001 as Monotherapy in the Palliative Treatment of Patients With TCC After Failure of Chemotherapy
Status: COMPLETED
Conditions: Transitional Cell Carcinoma
Interventions: DRUG: RAD001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suction Based Characterization of Healthy and Diseased Skin
Status: COMPLETED
Conditions: Systemic Sclerosis
Interventions: DEVICE: Measurment with Aspirational Medical Device|DEVICE: Measurment with Cutometer MPA 580
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure
Status: RECRUITING
Conditions: Supine Hypertension|Autonomic Failure
Interventions: OTHER: Tilt|OTHER: Elevated trunk|OTHER: Tilt - In home|OTHER: Elevated Trunk - In home
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Patient Decision Making for Treatment Choices Among Minorities With Lupus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: OTHER: Computerized patient decision-aid|OTHER: Usual care (lupus pamphlet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 1 Study Testing the Combination of Aflibercept and Capecitabine in Metastatic Digestive and Breast Cancers
Status: COMPLETED
Conditions: Metastatic Colorectal Cancers|Metastatic Gastric Cancers|Metastatic Oesophageal Cancers|Metastatic Pancreatic Cancers|Metastatic Biliary Cancers|Metastatic Breast Cancers
Interventions: DRUG: capecitabine|DRUG: aflibercept|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of an Educational and Explanatory Program for a Surgical Act on Preoperative Anxiety
Status: COMPLETED
Conditions: Preoperative Anxiety
Interventions: OTHER: Inclusion visit|OTHER: Nurse consultation|OTHER: Telephone contact|PROCEDURE: Coronarography on day 0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Diagnostic Value of 18F-FET PET/MRI for CNS Tumors in Children and Adolescents
Status: UNKNOWN
Conditions: Positron-Emission Tomography|Brain Neoplasms, Childhood
Interventions: DIAGNOSTIC_TEST: 18F-FET PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nitric Oxide Donors for Treatment of Isolated Oligohydramnios
Status: COMPLETED
Conditions: Isolated (Idiopathic) Oligohydramnios
Interventions: DRUG: isosorbide mononitrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low Level LASER Therapy in Chronic Stroke Patients With Spastic Planter Flexors.
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Low level LASER therapy|OTHER: Conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Machine Learning to Optimise the Danish Drowning Formula
Status: ACTIVE_NOT_RECRUITING
Conditions: Drowning|Drowning and Submersion While in Bath-Tub|Drowning and Submersion While in Natural Water|Drowning and Submersion While in Swimming-Pool|Drowning and Submersion Due to Fall Off Ship|Drowning and Nonfatal Submersion|Drowning, Near|Drowning; Asphyxia
Interventions: OTHER: Drowning incident
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Are Smokers Switching to Vaping at Lower Risk for Cancer? (Electronic Cigarettes and Cancer Risk)
Status: ACTIVE_NOT_RECRUITING
Conditions: Cigarette Smoking
Interventions: DEVICE: NIDA Standard Research E-cigarette (SREC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Efficacy, Safety and Tolerability of MIV-711 in Osteoarthritis Patients
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: MIV-711|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Decitabine and Arsenic Trioxide for Myelodysplastic Syndrome(MDS)
Status: WITHDRAWN
Conditions: Myelodysplastic Syndromes|P53 Mutation
Interventions: DRUG: Decitabine|DRUG: Arsenic Trioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Testing the Persuasiveness of Pro-inoculation Arguments
Status: COMPLETED
Conditions: Vaccination Hesitancy|Human Papillomavirus Vaccination|Vaccine Refusal
Interventions: BEHAVIORAL: Argument inoculation messages|BEHAVIORAL: Simple forewarning message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neuroimaging Approaches to Improve Prediction of Smoking Initiation and Nicotine Use Escalation Among Young Adult Electronic Nicotine Delivery Systems Users
Status: RECRUITING
Conditions: Message Exposure (Sequence: Regular Then Flavor)|Message Exposure (Sequence: Flavor Then Regular)|No Message Exposure (Control Condition)
Interventions: BEHAVIORAL: Exposure to Anti-Vaping Messages (generic themes then flavor-specific themes)|BEHAVIORAL: Exposure to Anti-Vaping Messages (flavor-specific themes then generic themes)|BEHAVIORAL: Exposure to Anti-Vaping Messages (no message exposure)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Frozen Embryo Transfer in Natural and Hormonal Replacement Cycles
Status: UNKNOWN
Conditions: Infertility
Interventions: BIOLOGICAL: frozen Embryo transfer|DRUG: 10,000U hCG injection|DRUG: GnRH agonist (Superfact)|DRUG: administration of 6 mg Estradiol valerate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Comparison of Cold Snare Polypectomy and Conventional Polypectomy
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: PROCEDURE: cold polypectomy|PROCEDURE: conventional polypectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standardization of Lead Placement for Sacral Neuromodulation. Part 1
Status: UNKNOWN
Conditions: Overactive Bladder|Non Obstructive Urinary Retention
Interventions: DIAGNOSTIC_TEST: Pelvic floor EMG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Surefire Catheter Versus Standard End-hole Microcatheter: A Pilot Study
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: Surefire® Infusion System|DEVICE: Standard End-hole catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Nationwide Observational Study Looking at Effectiveness and Bleeding Complications of NOACs vs. VKA in Non-valvular Atrial Fibrillation Patients.
Status: TERMINATED
Conditions: Non-valvular Atrial Fibrillation
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Apixaban (Eliquis)|DRUG: Dabigatran etexilate (Pradaxa)|DRUG: Warfarin (Marevan)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transcutaneous Spinal and Peripheral Stimulation and Wrist Robotic Therapy for Patients With Spastic Stroke
Status: TERMINATED
Conditions: Spasticity as Sequela of Stroke|Stroke|Stroke Sequelae|Hemiplegia, Spastic|Hemiparesis|Upper Limb Hypertonia|CVA
Interventions: DEVICE: MyoRegulator™ System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pharmacodynamic Effects of IT-pIL12-EP in Patients With TNBC
Status: COMPLETED
Conditions: ER-Negative PR-Negative HER2-Negative Breast Cancer
Interventions: BIOLOGICAL: IT-pIL12-EP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Movement Screen Differences in Male and Female Footballers as an Injury Prevention Tool.
Status: COMPLETED
Conditions: Sports Physical Therapy
Interventions: OTHER: Experimental group(Male)|OTHER: Experimental group(Female)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With Hepatitis Be Antigen (HBeAg) Positive Chronic Hepatitis B (CHB).
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: peginterferon alfa-2a [Pegasys]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Protocols for Magnesium Sulfate Maintenance Dose in Overweight and Obese Women Diagnosed With Preeclampsia
Status: NOT_YET_RECRUITING
Conditions: Severe Preeclampsia
Interventions: DRUG: maintenance magnesium sulphate1g/h|DRUG: maintenance magnesium sulphate2g/h
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endometrial Injury and Implantation Rates Before First ICSI Cycle
Status: COMPLETED
Conditions: Invitro Fertilization
Interventions: PROCEDURE: Endometrial scratch injury
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Evidence-Based Skin Care and Hydrocolloid Dressing in the Prevention of Nasogastric-Related Pressure Injury
Status: COMPLETED
Conditions: Medical Device Site Injury|Nasogastric Tube|Pressure Injury
Interventions: OTHER: skin care arm of where evidence-based practices in the implementation guide|DEVICE: hydrocolloid (Convatec Granuflex-extra thin) dressing|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Preemptive Analgesia With Amitryptyline for Prevention of Pain in Women After Hysterectomy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Amitriptyline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Brain Connectivity and Mindfulness Training in Youth With Bipolar Disorder Not Otherwise Specified (NOS)
Status: TERMINATED
Conditions: Bipolar Disorder, NOS
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction for Teens Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atraumatic Restorative Treatment (ART) in Early Childhood Caries (ECC)
Status: COMPLETED
Conditions: Early Childhood Caries
Interventions: PROCEDURE: Atraumatic Restorative Treatment (ART)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REASSURE: The Effect of Rimonabant on HbA1c in Overweight or Obese Patients With Type 2 Diabetes Not Adequately Controlled on 2 Oral Antidiabetic Agents
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Rimonabant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Oral Solithromycin Compared to Intramuscular Ceftriaxone Plus Oral Azithromycin in the Treatment of Patients With Gonorrhea
Status: COMPLETED
Conditions: Uncomplicated Urogenital Gonorrhea
Interventions: DRUG: solithromycin|DRUG: ceftriaxone|DRUG: azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nonpharmacological Pain Management in Neonates
Status: NOT_YET_RECRUITING
Conditions: Pain Management|Neonates Pain Management
Interventions: BEHAVIORAL: no intervention|DRUG: nonnutritive suckling|DRUG: oral glucose 25%|BEHAVIORAL: facilitated tuckling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of TST001, Nivolumab and Chemotherapy as First-line Therapy in Advanced or Metastatic GC/GEJ Adenocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer|Gastroesophageal-junction Cancer|Advanced Cancer
Interventions: DRUG: TST001, CapOx or mFOLFOX6 and NIVO or (Substudy) TST001, Oxaliplatin and capecitabine or 5-fluorouracil (5-FU)|DRUG: Placebo CapOx or mFOLFOX6 and NIVO or (Substudy) Placebo, Oxaliplatin and capecitabine or 5-fluorouracil (5-FU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Characterization of Multi-dose RVX000222 in Combination With Statin Treatment in Dyslipidemia
Status: TERMINATED
Conditions: Dyslipidemia|Coronary Artery Disease
Interventions: DRUG: RVX000222|DRUG: Rosuvastatin|DRUG: Atorvastatin|DRUG: Rosuvastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: GlideSheath Slender® Versus Conventional 6 French Arterial Sheath: Impact on the Distal Radial Artery Occlusion (SMART)
Status: RECRUITING
Conditions: Coronary Artery Disease|Cardiovascular Diseases
Interventions: DEVICE: GlideSheath Slender® and conventional arterial sheath|DEVICE: Conventional arterial sheath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Towards Neurobiology-based Diagnosis and Treatment of Affective Disorders
Status: UNKNOWN
Conditions: Affective Disorder
Interventions: DRUG: Escitalopram Pill|DRUG: Duloxetine|DRUG: Mirtazapine Pill|DRUG: Other Antidepressants
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immersive VR Reminiscence System for Facilitating Memory Retrieval Among Nursing Home Older Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Memory, Repressed|Emotional Regulation|Old Age
Interventions: COMBINATION_PRODUCT: Memo-gration|OTHER: Picture reminiscence therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Project 1, Study 2: The Combined Impact of Nicotine Replacement and Spectrum Cigarettes
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: BEHAVIORAL: Smoking research cigarettes with or without NRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Photodynamic Therapy and Microvesicles
Status: WITHDRAWN
Conditions: Photodynamic Therapy|Microvesicle Particle
Interventions: DEVICE: Photodynamic Therapy|DRUG: 4% Imipramine|DRUG: Base Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tolerability, Safety and Efficacy of Sigh Breaths During NIMV in Motor Neuron Disease
Status: UNKNOWN
Conditions: Motor Neuron Disease|Respiratory Failure|Amyotrophic Lateral Sclerosis
Interventions: DEVICE: NIMV with sigh breaths|DEVICE: Standard NIMV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of MAXOMAT ® on the Growth of Small Children to NOONAN's Syndrome
Status: COMPLETED
Conditions: Noonan Syndrome
Interventions: DRUG: MAXOMAT ®, biosynthetic growth hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Continuous Sciatic Nerve Block in Diabetic Foot Patients
Status: COMPLETED
Conditions: Diabetic Foot|Regional Anesthesia|Catheter Blockage|Wound Heal
Interventions: PROCEDURE: Group C (Continuous sciatic nerve block)|PROCEDURE: Group S (sciatic nerve block)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Efficacy and Safety of Apraglutide in SBS-IF
Status: COMPLETED
Conditions: Short Bowel Syndrome
Interventions: DRUG: apraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pomalidomide to Evaluate the Pharmacokinetics and Safety for Patients With Multiple Myeloma and Impaired Renal Function (POM Renal)
Status: COMPLETED
Conditions: Multiple Myeloma|Renal Impairment
Interventions: DRUG: 4 mg Oral POM + 40 mg Oral DEX|DRUG: 2 mg Oral POM + 40 mg Oral DEX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Omega 3 on Atrophic Vaginitis in Breast Cancer Survivors
Status: COMPLETED
Conditions: Ductal Breast Carcinoma in Situ|Breast Cancer, Stage I|Breast Cancer, Stage II|Breast Cancer, Stage III
Interventions: DIETARY_SUPPLEMENT: omega-3 fatty acid|OTHER: placebo|BEHAVIORAL: Questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Comparative Trial of a Modified Polyurethane Dressing and Aquacel
Status: COMPLETED
Conditions: Reepithelialization of Skin Graft Donor Sites
Interventions: DEVICE: modified polyurethane film dressing (OpSite, Smith&Nephew, London, UK)|DEVICE: Aquacel® (ConvaTec, Skillman, NJ, USA), sodium carboxy-methylcellulose hydrocolloid polymer dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study Investigating the Safety and Tolerability of Lu AF88434 in Healthy Young Men
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lu AF88434|DRUG: Lu AF99722 14C spiked dosage ([14C]-radiolabelled Lu AF88434)|DRUG: Lu AF99723 14C spiked dosage ([14C]-radiolabelled Lu AF88434)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Flavonoids and Caffeine Supplementation on Resting Metabolism
Status: COMPLETED
Conditions: Diet Modification
Interventions: DIETARY_SUPPLEMENT: Flavonoid, caffeine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Limb Occlusion Pressure Tourniquets to Decrease Pain After Surgery
Status: RECRUITING
Conditions: Limb Occlusion Pressure
Interventions: DEVICE: Experimental - Limb Occlusion pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Trial Comparing Metered Dose Inhalers and Breath Actuated Nebulizers
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: Metered Dose Inhaler|DEVICE: Breath Actuated Nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biokinetics Study for F-18 FDG in Pediatric Molecular Imaging
Status: WITHDRAWN
Conditions: Childhood Neoplasm
Interventions: OTHER: Modification in acquisition protocol|DRUG: F-18 Fluorodeoxyglucose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Implication for Strategies of Long Term Control of Viral Replication in Patient With Primary HIV Infection (PHI).
Status: UNKNOWN
Conditions: HIV-1-infection
Interventions: COMBINATION_PRODUCT: SYMTUZA|COMBINATION_PRODUCT: DESCOVY+DOLUTEGRAVIR|COMBINATION_PRODUCT: SYMTUZA+DOLUTEGRAVIR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk of Infection of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), COVID-19, in a Massive Musical Show With Transmission Prevention Measures
Status: COMPLETED
Conditions: COVID-19 (SARS-CoV-2)
Interventions: BEHAVIORAL: Participate in a massive musical event
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Feasibility And Efficacy Of A Telerehabilitation Program For People With Knee Osteoarthiritis In Sri Lanka
Status: ENROLLING_BY_INVITATION
Conditions: Knee Osteoarthritis
Interventions: OTHER: Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of AC0058TA in Healthy Male and Female Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AC0058TA|DRUG: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Artificial Sweetener (AFS) on Glucose Metabolism in Patients With Type 1 Diabetes (T1D)
Status: NOT_YET_RECRUITING
Conditions: Type 1 Diabetes (T1D)|Healthy Subjects
Interventions: OTHER: Sweet taste perception with/without sweet taste blockade
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Continuous EKG Monitoring Using S-Patch Ex : Prospective Observational Study (S-patch Registry)
Status: UNKNOWN
Conditions: Patient With Atrial Fibrillation or High Stroke Risk
Interventions: DEVICE: continous 3 day EKG monitoring with S-Patch Cardio
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Consumption Effect of Probiotic Products on Salivary Cariogenic Bacterial Counts in Preschool Children.
Status: UNKNOWN
Conditions: Dental Caries
Interventions: DIETARY_SUPPLEMENT: (L. reuteri Prodentis®).|DIETARY_SUPPLEMENT: Placebo lozenges
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Open-label PET Study With [11C]Osimertinib in Patients With EGFRm NSCLC and Brain Metastases
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Osimertinib|DRUG: [11C]osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Percutaneous Transhepatic Cholangiography Versus Endoscopic Ultrasound Guided Biliary Drainage
Status: UNKNOWN
Conditions: Malignant Biliary Obstruction
Interventions: PROCEDURE: Percutaneous transhepatic cholangiography vs. endoscopic biliary drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Following Subcutaneous Injection of JNJ-64304500 in Healthy Japanese and Caucasian Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-64304500|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Guided Tissue Regeneration in Healing of Through and Through Periapical Lesion
Status: UNKNOWN
Conditions: Periapical Lesion
Interventions: PROCEDURE: Periapical surgery with guided tissue regeneration|PROCEDURE: Periapical surgery without anyguided tissue regeneration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gene Therapy in Treating Women With Refractory or Relapsed Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer
Status: UNKNOWN
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: herpes simplex thymidine kinase|DRUG: ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of Intravenous Levosimendan Efficacy in the Short Term Treatment of Decompensated Chronic Heart Failure.
Status: COMPLETED
Conditions: Heart Failure, Congestive
Interventions: DRUG: Levosimendan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: NIV Application in the Treatment of Asthmatic Children
Status: COMPLETED
Conditions: Asthma|Child|Bronchial Spasm
Interventions: DEVICE: muscle training|DEVICE: Continue Positive Airway Pressure|DEVICE: bilevel positive airway pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Phaco/IOL Versus Phaco/IOL + Goniosynechialysis in Subjects With PACG
Status: COMPLETED
Conditions: Glaucoma, Angle-closure
Interventions: PROCEDURE: Phaco/IOL|PROCEDURE: Phaco/IOL + goniosynechialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study of TVP-1012 (1 mg) in Early Parkinson's Disease Patients
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: TVP-1012|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laminaria Tents Versus Vaginal Prostaglandin in Cervical Ripening
Status: COMPLETED
Conditions: Labor Onset and Length Abnormalities
Interventions: DEVICE: Laminaria|DRUG: Vaginal prostaglandin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Evaluating Oat Polyphenols on Post-prandial Glucose Response
Status: COMPLETED
Conditions: Blood Glucose
Interventions: OTHER: Serving of oatmeal made from low avenanthramides oats and water|OTHER: Serving of oatmeal made from high avenanthramides oats and water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial to Evaluate the Efficacy of Orbital Radiotherapy in Graves' Orbitopathy
Status: NOT_YET_RECRUITING
Conditions: Thyroid Associated Ophthalmopathy
Interventions: RADIATION: Orbital radiotherapy|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Amitriptyline on Learning in a Visual Discrimination Task
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Amitriptyline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Trial of 2% Chlorhexidine Bathing on Nosocomial Infections in the Surgical Intensive Care Unit
Status: COMPLETED
Conditions: Cross Infection|Pneumonia, Ventilator-associated|Catheter-related Infections|Infection Due to Indwelling Urinary Catheter|Surgical Wound Infection
Interventions: DRUG: Chlorhexidine gluconate|OTHER: Standard bathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dopaminergic Modulation of Cognition and Psychomotor Function
Status: COMPLETED
Conditions: Dopamine Activity|Episodic Memory Consolidation|Response Preparation
Interventions: DRUG: Methylphenidate 40 mg|DRUG: Levodopa/carbidopa 125 mg|DRUG: Domperidon 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combined Effect of Laser Acupuncture and Electroacupuncture in Knee Osteoarthritis Patients
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Laser Acupuncture|DEVICE: Sham Laser Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of ISIS EIF4E Rx in Combination With Docetaxel and Prednisone (CRPC)
Status: COMPLETED
Conditions: Castrate-Resistant Prostate Cancer
Interventions: DRUG: ISIS EIF4E Rx|DRUG: ISIS EIF4E Rx|DRUG: ISIS EIF4E Rx|DRUG: Prednisone|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panretinal Photocoagulation for Diabetic Retinopathy With PASCAL Laser
Status: UNKNOWN
Conditions: Diabetic Retinopathy
Interventions: PROCEDURE: Panretinal photocoagulation|PROCEDURE: Panretinal photocoagulation|PROCEDURE: Panretinal photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of the Cawthorne and Cooksey Exercise Program on Balance, Fear of Falling and Dizziness on Daily Life in Older Adults
Status: COMPLETED
Conditions: Older Adults|Accidental Falls|Prevention|Exercise
Interventions: OTHER: Cawthorne and Cooksey exercise program|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Standing Persistant Atrial Fibrillation-Pulmonary Vein Isolation With or Without Ablation
Status: COMPLETED
Conditions: Atrial Fibrillation|Tachycardia
Interventions: PROCEDURE: pulmonary vein isolation|PROCEDURE: pulmonary vein isolation with additional ablation of fragmented potentials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intravenous n-3 Fatty Acids and Sudden Cardiac Death in Hemodialysis Patients
Status: COMPLETED
Conditions: Renal Failure, Chronic
Interventions: DRUG: lipid emulsion with a high content of n-3 fatty acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pentoxifylline Treatment in Acute Pancreatitis (AP)
Status: COMPLETED
Conditions: Acute Pancreatitis (AP)|Gallstone Pancreatitis|Alcoholic Pancreatitis|Trauma Acute Pancreatitis|Hypertriglyceridemia Acute Pancreatitis|Idiopathic (Unknown) Acute Pancreatitis|Medication Induced Acute Pancreatitis|Cancer Acute Pancreatitis|Miscellaneous (i.e. Acute on Chronic Pancreatitis)
Interventions: DRUG: Pentoxifylline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of tDCS for Swallowing Difficulties in Stroke Patients
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: Eldith DC-STIMULATOR|DEVICE: Sham Eldith DC-STIMULATOR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Preoperative Melatonin in Reducing the Inhaled Isoflurane Requirements in Open Nephrectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Melatonin 5 mg|DRUG: Sugar Coated Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of the Gut Barrier and Blood Vessel Inflammation in Individuals With and Without HIV
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Teduglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telehealth Education Leveraging Electronic Transitions Of Care for COPD Patients
Status: NOT_YET_RECRUITING
Conditions: COPD Exacerbation|Care Transitions
Interventions: OTHER: Virtual at Home Medication Reconciliation Visit(s)|BEHAVIORAL: Virtual At Home Medication Education Visit(s)|OTHER: COPD advanced practice nurse Inpatient Consult|OTHER: Inpatient Medication Reconciliation|OTHER: Post-discharge nurse 48 hour phone follow-up call|OTHER: Post-discharge follow-up advanced practice nurse outpatient visit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Escalating Multiple Doses of TAK-831 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TAK-831 Tablet T2|DRUG: Placebo|DRUG: TAK-831 Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Atezolizumab and Vigil in Patients With Advanced Gynecological Cancers
Status: COMPLETED
Conditions: Advanced Gynecological Cancers|Ovarian Cancer|Cervical Cancer|Uterine Cancer
Interventions: BIOLOGICAL: Vigil|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing Individualism and Collectivism
Status: COMPLETED
Conditions: Individual Difference
Interventions: OTHER: Online prime (statements writing)|OTHER: Online prime (circling)|OTHER: Online prime (Sumarian Warrior)|OTHER: Online prime (all)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Effectiveness of Two Different Electrotherapy Agents on Central Sensitization
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Transcutaneous Electrical Nerve Stimulation|DEVICE: Interferential Current|OTHER: Hydrocollator hot-pack|DEVICE: Sham transcutaneous Electrical Nerve Stimulation|DEVICE: Sham interferential Current
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of AP23573 in Patients With Relapsed or Refractory Hematologic Malignancies (8669-024)(COMPLETED)
Status: COMPLETED
Conditions: Hematologic Malignancies|Leukemia|Myelodysplastic Syndromes|Myeloid Metaplasia|Lymphoma
Interventions: DRUG: ridaforolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Health Belief Model-Based Cancer Education on Cancer Information Load, Knowledge and Attitudes Towards Cancer Screenings
Status: NOT_YET_RECRUITING
Conditions: Cancer|Education|Caregiver|Randomised Controlled Trial
Interventions: OTHER: Cancer education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Clinical Genetics and Screening for Idiopathic Pulmonary Fibrosis
Status: NOT_YET_RECRUITING
Conditions: Familial Pulmonary Fibrosis|Idiopathic Pulmonary Fibrosis
Interventions: DIAGNOSTIC_TEST: High resolution Computed Tomography (HRCT) scans of the Chest|DIAGNOSTIC_TEST: Pulmonary Function Testing (PFTs)|DIAGNOSTIC_TEST: Digital lung sounds auscultation|DIAGNOSTIC_TEST: Laboratory Assessments|GENETIC: DNA sequencing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multiple Oral Doses of BI 207127 NA in Treatment naïve and Treatment-experienced Hepatitis C Virus (HCV)-Infected Patients
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: BI 207127 NA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: mitomycin C|DRUG: tretinoin|DRUG: vinorelbine tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Impact of Enteral Versus Oral Protein Feeding on Muscle Protein Synthesis in Healthy Young Males and Females
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Oral Placebo|OTHER: Oral Protein|OTHER: Enteral Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Assess Effects of Arbaclofen ER Tablets Compared With Placebo on Sperm Parameters in Male Subjects With MS
Status: WITHDRAWN
Conditions: Multiple Sclerosis|Sperm
Interventions: DRUG: arbaclofen ER Tablets|DRUG: Placebo for arbaclofen ER tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Analgesic Contribution of the Suprazygomatic Maxillary Nerve Block for Cleft Palate Surgery in Children
Status: WITHDRAWN
Conditions: Cleft Palate|Surgery
Interventions: DRUG: suprazygomatic maxillary nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Ulcerative Colitis With a Combination of Lactobacillus Rhamnosus and Lactobacillus Acidophilus.
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: BEHAVIORAL: Administration of probiotic (L. rhamnosus and L. acidophilus)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: OH2 Oncolytic Viral Therapy in Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor|Gastrointestinal Cancer
Interventions: BIOLOGICAL: OH2 injection, with or without irinotecan or HX008
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gait and Postural Balance Analysis During Head-motion Perturbed Standing and Walking in Older Adults
Status: RECRUITING
Conditions: Aged|Accidental Fall|Postural Balance|Gait
Interventions: DIAGNOSTIC_TEST: Cognition|DIAGNOSTIC_TEST: Sensory function|DIAGNOSTIC_TEST: Frailty|OTHER: Biomechanical movement analysis|OTHER: Screening|OTHER: Follow up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I Study to Evaluate the Safety, Pharmacokinetics and Antitumor Activity of HC010 in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: HC010
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Validation and Restoration of Immune Dysfunction in Severe Infections and Sepsis
Status: COMPLETED
Conditions: Sepsis|Macrophage Activation Syndrome
Interventions: DRUG: Anakinra|DRUG: Recombinant human interferon-gamma|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Achilles Tendinopathy, Treatment With eXercise Comparing Men and Women
Status: COMPLETED
Conditions: Achilles Tendinopathy|Achilles Tendonitis|Achilles Tendon Pain|Achilles Degeneration|Achillodynia
Interventions: OTHER: Exercise treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Booster Dose of a Tetravalent Dengue Vaccine in Subjects Who Previously Completed the 3-dose Schedule
Status: COMPLETED
Conditions: Dengue Fever|Dengue Hemorrhagic Fever
Interventions: BIOLOGICAL: CYD Dengue Vaccine (5-dose formulation)|BIOLOGICAL: Placebo, NaCl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION