pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Safety and Efficacy Study of Dapsone Gel in Patients With Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Dapsone Gel|DRUG: Dapsone Gel Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3002813 in Participants With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: BIOLOGICAL: LY3002813-IV|BIOLOGICAL: LY3002183-SC|DRUG: Placebo-IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dokimos Plus Aortic Valve Implant in 80 Patients Diagnosed With a Heart Valve Disease and Requiring Valve Replacement
Status: TERMINATED
Conditions: Stenosis|Regurgitation, Aortic
Interventions: DEVICE: Dokimos Plus aortic valve
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MoST-Influenced Behavioral Intervention for Walking
Status: RECRUITING
Conditions: Cardiovascular Diseases|Physical Inactivity
Interventions: BEHAVIORAL: Goal Setting|BEHAVIORAL: Action Planning|BEHAVIORAL: Self-Monitoring of Behavior|BEHAVIORAL: Feedback on Behavior
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Modulation of Bifidocentric Dysbiosis Through Bifidobacterium Bifidum PRL2010 Supplementation in Caesarian-born Infants
Status: COMPLETED
Conditions: Disbiosis
Interventions: DIETARY_SUPPLEMENT: Probiotic Bifidobacterium Bifidum PRL2010|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FamilyLink and Breastfeeding
Status: COMPLETED
Conditions: Breastfeeding
Interventions: BEHAVIORAL: FamilyLink Pumping|BEHAVIORAL: Standard Pumping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Palbociclib and Endocrine Therapy for LObular Breast Cancer Preoperative Study (PELOPS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Letrozole|DRUG: Tamoxifen|DRUG: Palbociclib|DRUG: Endocrine Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy Verse Surgery Alone After Stent Placement for Obstructive Colonic Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer|Neoadjuvant Chemotherapy|Stent|Obstruction
Interventions: DEVICE: Stenting with neoadjuvant chemotherapy|DEVICE: Stenting with immediate Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics on Helicobacter Pylori Eradication
Status: UNKNOWN
Conditions: Helicobacter Pylori Eradication
Interventions: DRUG: Bifidobacterium tetrad live bacteria tablet plus Helicobacter pylori quadruple eradication therapy|DRUG: Bifidobacterium tetrad live bacteria tablet placebo plus Helicobacter pylori quadruple eradication therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Kyaterekera Project: A Combination Intervention Addressing Sexual Risk-Taking Behaviors Among Vulnerable Women in Uganda
Status: COMPLETED
Conditions: Control arm_Bolstered Care|Treatment arm_HIVRR+S+FL|Treatment arm_HIVRR+S+FLM
Interventions: BEHAVIORAL: HIV Risk Reduction|BEHAVIORAL: Financial Literacy|BEHAVIORAL: Mentorship|BEHAVIORAL: Matched savings individual development account
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exocrine Pancreatic Insufficiency After Acute Pancreatitis and Pancreatic Enzyme Replacement Therapy
Status: RECRUITING
Conditions: Acute Pancreatitis|Exocrine Pancreatic Insufficiency|Gut Microbiota|Immunology
Interventions: DRUG: Pancreatic Enzyme Replacement Therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of BI 1356 After Co-administration With Ritonavir Compared to the Bioavailability of BI 1356 Alone in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1356|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Open, Non-controlled Clinical Investigation to Evaluate the Performance and Safety of an Antimicrobial Foam Transferring Dressing in Patients With Malignant Wounds
Status: COMPLETED
Conditions: Malignant Wounds
Interventions: DEVICE: Mepilex Transfer Ag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Embolization of Thyroid Arteries as a Treatment for Different Thyroid Disorders
Status: NOT_YET_RECRUITING
Conditions: Graves Disease|Goiter, Nodular|Goiter Malignant|Goiter Diffuse
Interventions: PROCEDURE: selective embolization of thyroid arteries (SETA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Telematic Program for Optimization of Metabolic Control in Diabetes Mellitus Type 1 (DM1) Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Metabolic Disorder
Interventions: OTHER: Control|DEVICE: Telecare system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rotator Cuff Integrity and Clinical Outcomes 5 Years After Repair.
Status: RECRUITING
Conditions: Rotator Cuff Tears|Rotator Cuff Injuries|Rotator Cuff Tear or Rupture, Not Specified as Traumatic
Interventions: DIAGNOSTIC_TEST: Ultrasonography imaging|DIAGNOSTIC_TEST: American Shoulder and Elbow Surgeons (ASES) Score|DIAGNOSTIC_TEST: The Constant-Murley score (CMS)|DIAGNOSTIC_TEST: The Disabilities of the Arm, Shoulder and Hand (DASH)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Nimotuzumab in Combination With Radio-chemotherapy for the Treatment of Brainstem Tumor in Children
Status: UNKNOWN
Conditions: Childhood Brain Stem Neoplasm
Interventions: DRUG: Nimotuzumab|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hypertonic Saline on the Lung Clearance Index in Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: hypertonic saline (7 %) and isotonic saline (0.9%)|DRUG: hypertonic saline (7 %) and isotonic saline (0.9%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: C-reactive Protein Information and Blood Cultures for Emergency Department Patients With Sepsis
Status: UNKNOWN
Conditions: Sepsis|Infection|Bacteremia
Interventions: OTHER: CRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sardine-enriched Diet for Prevention Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|PreDiabetes|Diet Habit|Diabetes|Nutritional and Metabolic Disease
Interventions: DIETARY_SUPPLEMENT: Sardine|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vitamin K2 Intervention in Patients With Vitamin K Antagonists
Status: COMPLETED
Conditions: Thrombosis
Interventions: DIETARY_SUPPLEMENT: Vitamin K2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Studying Tumor Tissue Samples From Patients With Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: GENETIC: DNA analysis|GENETIC: gene expression analysis|GENETIC: protein expression analysis|GENETIC: reverse transcriptase-polymerase chain reaction|GENETIC: western blotting|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prebiotic vs Probiotic in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Clinically Isolated Syndrome (CIS)
Interventions: DIETARY_SUPPLEMENT: Prebiotics (Prebiotin Prebiotic Fiber Stick Pac)|DIETARY_SUPPLEMENT: Probiotics (Visbiome®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Synchrony in the Post-operative Patient
Status: COMPLETED
Conditions: Patient-ventilator Asynchronism
Interventions: DEVICE: MAQUET SERVOi ventilator with Edi Catheter|DEVICE: MAQUET SERVOi ventilator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Deferasirox in Non-transfusion Dependent Thalassemia Patients With Iron Overload and a One Year Open-label Extension Study
Status: COMPLETED
Conditions: Non-transfusion Dependent Thalassemia
Interventions: DRUG: deferasirox|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)
Status: RECRUITING
Conditions: Alpha1-Antitrypsin Deficiency
Interventions: DRUG: Fazirsiran Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of HPV-16/18 Vaccine (GSK 580299) to Prevent HPV-16 and/or -18 Cervical Infection in Young Healthy Women
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: Cervarix|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Efficacy and Safety of GB-0998 in Patients With Unexplained Recurrent Miscarriage
Status: COMPLETED
Conditions: Recurrent Miscarriage
Interventions: DRUG: GB-0998|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glutamate-Glutamine Cycling (VCYC) During Cocaine Abstinence Using 1H-MRS
Status: COMPLETED
Conditions: Cocaine Dependence|Healthy
Interventions: DRUG: N-acetyl cysteine|DIAGNOSTIC_TEST: [18F]FDG PET scan|DIAGNOSTIC_TEST: 1H MRS|DIAGNOSTIC_TEST: [11C]APP311 PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of an HIV Vaccine in HIV-Negative Adults in North America Who Are at Risk of HIV Infection
Status: COMPLETED
Conditions: HIV Infections|HIV Seronegativity
Interventions: BIOLOGICAL: MN rgp120/HIV-1 and GNE8 rgp120/HIV-1
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: CD3/CD28 Bead Activated T-Cells Following Chemo-Immunotherapy in Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: Infusion of CD3/CD28 stimulated T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet-based Psychodynamic Therapy Compared to Behavioral Activation - a Randomized Controlled Trial
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Internet-based Psychodynamic Therapy|BEHAVIORAL: Internet-based Behavioral Activation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of a Short-Term High Fat or Low Fat Diet on Intestinal Genes Expression Involved in the Cholesterol and Fatty Acid Metabolism
Status: COMPLETED
Conditions: Gene Expression
Interventions: OTHER: 3-days high fat diet|OTHER: 3-days low fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacologic Response and Safety of Inhaled Insulin in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: inhaled human insulin (INH)|DRUG: sc insulin lispro (LIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: 123-I mIBG (AdreView) Heart-to-Mediastinal (H/M) Ratio and SPECT Imaging on a Small Field of View-High Efficiency Cardiac SPECT System
Status: COMPLETED
Conditions: Heart Failure|Cardiomyopathy
Interventions: DRUG: AdreView|OTHER: Single Photon Emission Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SGLT2 Inhibitors and Metformin on Metabolism and Non-Alcoholic SteatoHepatitis
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DRUG: Metformin|DRUG: SGLT2 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fluoride Intake From Toothbrushig With Children's or Regular Toothpastes
Status: COMPLETED
Conditions: Healthy Individuals
Interventions: DRUG: Regular toothpastes|DRUG: Children's toothpastes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nodal Burden and Nodal Recurrence in Patients With Isolated Tumor Cells After Neoadjuvant Chemotherapy Treated With Axillary Dissection or Nodal Radiation: the OPBC-05/EUBREAST-14R/ICARO Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: Observational study no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of the Mediterranean Diet on Patients With Psoriasis
Status: RECRUITING
Conditions: Psoriasis|Psoriasis Vulgaris|Hyperlipidemias|Depression|Anxiety|Metabolic Syndrome|Obesity
Interventions: OTHER: High-intensity Mediterranean diet intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maternal-fetal Immune Responses to Fetal Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Spina Bifida|Congenital Diaphragmatic Hernia|Lower Urinary Tract Obstructive Syndrome|Myelomeningocele
Interventions: OTHER: Blood and placenta specimen collection.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Corneal Collagen Crosslinking for Progressive Keratoconus and Ectasia Using Riboflavin/Dextran and Hypotonic Riboflavin
Status: ACTIVE_NOT_RECRUITING
Conditions: Keratoconus|Corneal Ectasia
Interventions: DRUG: Riboflavin/Dextran|DRUG: Hypotonic Riboflavin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compassionate Same-Day Evaluation & Delivery of XRT for Bony Metastasis in Hospice Patients
Status: TERMINATED
Conditions: Symptomatic Osseous Bone Lesions From Any Malignancy
Interventions: RADIATION: Radiation Therapy|OTHER: Quality-of-Life Assessment|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transfusion Trigger After Operations in High Cardiac Risk Patients
Status: COMPLETED
Conditions: Myocardial Infarction|Coronary Revascularization|Acute Renal Failure
Interventions: PROCEDURE: Blood Transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Stimulation of Acupuncture Points by Athermic Laser Therapy for the Prevention of Chemotherapy Induced Nausea and Vomiting in Children
Status: COMPLETED
Conditions: Children|Chemotherapy-induced Nausea and Vomiting|Malignant Tumor
Interventions: OTHER: laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study on the Treatment of Degenerative Lumbar Spine Stenosis With a Percutaneous Interspinous Implant
Status: TERMINATED
Conditions: Lumbar Spinal Stenosis
Interventions: PROCEDURE: Spacer|OTHER: physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II, Randomized, Placebo-Controlled Study of ATI-7505 in Patients With Chronic Idiopathic Constipation
Status: TERMINATED
Conditions: Chronic Constipation
Interventions: DRUG: ATI-7505|DRUG: ATI-7505|DRUG: ATI-7505|DRUG: ATI-7505|DRUG: ATI-7505
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sofosbuvir/Velpatasvir Treatment of Chronic Hepatitis C During Pregnancy
Status: RECRUITING
Conditions: Hepatitis C, Chronic|Pregnancy; Infection
Interventions: DRUG: Sofosbuvir/Velpatasvir 400 MG-100 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sacral Neuromodulation for Male Overactive Bladder (MOAB)
Status: NOT_YET_RECRUITING
Conditions: Overactive Bladder|Urinary Urgency Incontinence|Benign Prostatic Hyperplasia|Prostate Cancer|Prostatectomy
Interventions: DEVICE: Axonics SNM System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Maintenance Benefits of a Pulmonary Rehabilitation Program Using a Mobile Digital Solution: a Prospective, Randomized, Controlled, Multicenter Study in a Population of COPD Patients
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: telerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous and Epidural Stimulation in SCI
Status: WITHDRAWN
Conditions: Paraplegia, Spinal|Paraplegia, Complete|Paraplegia; Traumatic
Interventions: DEVICE: Transcutaneous spinal cord stimulator|DEVICE: Epidural spinal cord stimulator system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nintedanib in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Failed Up to Two Previous Chemotherapy Regimens
Status: COMPLETED
Conditions: Recurrent Non-small Cell Lung Cancer|Squamous Cell Lung Cancer|Stage III Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: nintedanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: What's Hopping? Cricket Protein and Human Gut Microbiota
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Cricket Protein Powder|OTHER: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Lung and Diaphragm Ultrasound Evaluation During Weaning From Mechanical Ventilation in COVID-19 Patients
Status: COMPLETED
Conditions: Weaning|COVID-19|Lung Ultrasound|Diaphragm Ultrasound
Interventions: OTHER: Point-of-Care Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I Trial of Biweekly Gemcitabine & Paclitaxel & Low-Dose Radiation for Metastatic or Recurrent Head & Neck Cancer
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DRUG: gemcitabine|DRUG: paclitaxel|RADIATION: radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Therapeutic Touch on Functional Constipation in Infants and Young Children
Status: RECRUITING
Conditions: Functional Constipation|Therapeutic Touch|Infants|Children|Constipation
Interventions: BEHAVIORAL: Therapeutic Touch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Evaluation of Compomer and Composite Class II Restorations in Primary Molars: 24 Months Results
Status: COMPLETED
Conditions: Primary Teeth
Interventions: OTHER: Dyract XP (Dentsply De Trey), Kerr Herculite Classic (Kerr Corporation),R&D Series NOVA(Kuraray Medical Inc) Clearfil TM SE Bond (Kuraray Medical),Hydrocal LC (Medicept Dental)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Tolerance of Conjugate Meningococcal C Vaccine in Infants
Status: COMPLETED
Conditions: Meningitis, Meningococcal
Interventions: BIOLOGICAL: Meningococcal C|BIOLOGICAL: DTP/Hib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Target Fortification of Breast Milk: How Often Breast Milk Needs to be Measured?
Status: UNKNOWN
Conditions: Postnatal Growth Disorder
Interventions: DIETARY_SUPPLEMENT: Fortification with modular protein|DIETARY_SUPPLEMENT: Fortification with modular carbohydrate|DIETARY_SUPPLEMENT: Fortification with modular fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Imaging of Gastric Cancer Metastatic Lymph Nodes with 99mTc-3PRGD2 Probe.
Status: NOT_YET_RECRUITING
Conditions: Stomach Neoplasm|Lymph Node Metastasis|RADIONUCLIDE IMAGING
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Low-dose Ketamine and Postpartum Depression in Parturients With Prenatal Depression
Status: COMPLETED
Conditions: Perinatal Depression|Ketamine|Cesarean Delivery|Postpartum Depression
Interventions: DRUG: Ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of a New Antimicrobial Dressing on Wound Healing and Incidence of Sternal Wound Infections
Status: TERMINATED
Conditions: Surgical Wound Infection
Interventions: DEVICE: TELFA™ A.M.D. Island dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Comparative Evaluation of Pharmacokinetics After CKD-501 Between Renal Impaired and Normal Renal Function Subjects
Status: COMPLETED
Conditions: Renal Impairment|Healthy
Interventions: DRUG: CKD-501
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of EnteraGam In People With COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: DIETARY_SUPPLEMENT: Bovine Plasma-Derived Immunoglobulin Concentrate|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Sickle Cell Kidney Disease
Status: TERMINATED
Conditions: Anemia, Sickle Cell|Sickle Cell Disease|Kidney Disease|Hypertension|Proteinuria
Interventions: DRUG: Losartan|DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing the Efficacy of Insulin Degludec With Insulin Glargine on Glycaemic Control Using Continuous Glucose Monitoring in Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Sensitivity of the Hypothalamic GnRH Pulse Generator to Estradiol and Progesterone Inhibition
Status: ACTIVE_NOT_RECRUITING
Conditions: Hyperandrogenemia|Polycystic Ovary Syndrome (PCOS)
Interventions: DRUG: estrace|DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Myeloma XIV: Frailty-adjusted Therapy in Transplant Non-Eligible Patients With Newly Diagnosed Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: R1: Ixazomib, Lenalidomide, Dexamethasone (IRD) induction therapy - reactive arm|DRUG: R1: Ixazomib, Lenalidomide, Dexamethasone (IRD) induction therapy - adaptive arm|DRUG: R2: Lenalidomide plus placebo maintenance|DRUG: R2: Lenalidomide + ixazomib maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Nerve Stimulation Post-thoracic Surgery in a Intensive Care Unit
Status: UNKNOWN
Conditions: Thoracic Surgery
Interventions: PROCEDURE: Conventional physiotherapy Group|PROCEDURE: TENS Group|PROCEDURE: Placebo TENS group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Safety of CB-5339 in Patients With Cancer
Status: WITHDRAWN
Conditions: Aggressive Non-Hodgkin Lymphoma|Indolent Non-Hodgkin Lymphoma|Locally Advanced Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm
Interventions: DRUG: p97 Inhibitor CB-5339 Tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Visual Biofeedback Therapy in Parkinson's Patients
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DEVICE: Visual Biofeedback Therapy|BEHAVIORAL: Conventional Balance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Very Early Surfactant and NCPAP for Premature Infants With RDS
Status: COMPLETED
Conditions: Respiratory Distress Syndrome|Pneumothorax/Pulmonary Intersticial Emphysema|Chronic Lung Disease
Interventions: OTHER: Very early surfactant and bubble NCPAP|OTHER: bubble NCPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parenting for Lifelong Health - Thailand
Status: COMPLETED
Conditions: Parent Child Abuse|Domestic Violence|Child Behavior Problem|Child Neglect|Depression, Anxiety|Parent-Child Relations|Parenting|Parent-child Problem
Interventions: BEHAVIORAL: PLH-Thailand parenting programme|OTHER: Control (care as usual)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oral Bioequivalence Study of PL 3100 and Naproxen in Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Naproxen|DRUG: PL 3100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Jones Technique and Cross Friction Massage on Cervicogenic Headache.
Status: NOT_YET_RECRUITING
Conditions: Cervicogenic Headache
Interventions: OTHER: Jones technique|OTHER: Cross-friction massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Observe the Effectiveness and Safety of Ranibizumab in Real Life Setting
Status: COMPLETED
Conditions: Wet Age Related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion|Wet Age Related Macular Degeneration|Diabetic Macular Edema|Retinal Vein Occlusion
Interventions: DRUG: Ranibizumab|OTHER: Ranibizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Alpha1-Proteinase Inhibitor (Human), Modified Process (Alpha-1 MP) in Subjects With Pulmonary Emphysema Due to Alpha1 Antitrypsin Deficiency (AATD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Emphysema in Alpha-1 PI Deficiency
Interventions: BIOLOGICAL: Alpha-1 MP|OTHER: 0.9% Sodium Chloride for Injection, USP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sentinel Node Biopsy Following NeoAdjuvant Chemotherapy in Biopsy Proven Node Positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Invasive Breast Cancer
Interventions: PROCEDURE: Sentinel Lymph Node Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Life Review Intervention on Meaning in Life Among Older Adults With Disabilities
Status: ENROLLING_BY_INVITATION
Conditions: Disabilities, Psychological
Interventions: BEHAVIORAL: Life review|BEHAVIORAL: Routine community health services
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment for Parkinson Disease
Status: COMPLETED
Conditions: Transcranial Magnetic Stimulation|Functional Magnetic Resonance Imaging|Parkinson Disease
Interventions: OTHER: transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acids as Regulators of Brown Adipose Tissue During Cold Exposure
Status: RECRUITING
Conditions: Cold Exposure
Interventions: DIETARY_SUPPLEMENT: Fish Oil|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Effectiveness of Live Zoster Vaccine in Anti-Tumor Necrosis Factor (TNF) Users (VERVE Trial)
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Inflammatory Arthritis|Arthritis|Psoriatic Arthritis|Psoriasis|Ankylosing Spondylitis|Enteropathic Arthritis|Crohn's Disease
Interventions: BIOLOGICAL: Herpes Zoster (HZ) Vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Protocol Number: HJKC3-0003. Treatment Free Remission After Combination Therapy With Asciminib (ABL001) Plus Tyrosine Kinase Inhibitors (TKI) in Chronic Phase Chronic Myeloid Leukemia (CP-CML) Patients Who Relapsed After a Prior Attempt at TKI Discontinuation
Status: RECRUITING
Conditions: Chronic Phase Chronic Myelogenous Leukemia
Interventions: DRUG: Asciminib 40 MG|DRUG: Asciminib 40 MG Twice Daily|DRUG: Asciminib 80 MG daily|DRUG: Imatinib|DRUG: Nilotinib|DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmetomedine for Post Operative Delirium in Elderly Patients Undergoing Elective Total Knee Replacement Under Spinal Anesthesia
Status: COMPLETED
Conditions: Postoperative Delirium
Interventions: DRUG: dexmetomedine infusion|DRUG: Dexmetomedine infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Use of a Dynamic Compression Intramedullary Nail for Tibiotalocalcaneal Arthrodesis
Status: UNKNOWN
Conditions: Ankle Arthritis|Foot Arthritis
Interventions: PROCEDURE: Tibiotalocalcaneal (TTC) arthrodesis|DEVICE: DynaNail
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Dietary Erythritol on Platelet Reactivity and Vascular Inflammation
Status: RECRUITING
Conditions: Platelet Aggregation, Spontaneous|Vascular Thrombosis
Interventions: OTHER: Erythritol|OTHER: Aspartame
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacodynamic Biomarkers of Standard Anti-microtubule Drugs as Assessed by Early Tumor Biopsy
Status: TERMINATED
Conditions: Breast Cancer|Breast Neoplasms
Interventions: DRUG: Taxane|DRUG: Vinorelbine|DRUG: Ixabepilone|DRUG: Eribulin|DRUG: Chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD0328 in Elderly Healthy Subjects
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: AZD0328|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hypofractionated Partial Breast Irradiation in Treating Patients With Early Stage Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Ductal Breast Carcinoma In Situ|Early-Stage Breast Carcinoma|Invasive Breast Carcinoma|Stage 0 Breast Cancer AJCC v6 and v7|Stage I Breast Cancer AJCC v7|Stage IA Breast Cancer AJCC v7|Stage IB Breast Cancer AJCC v7|Stage II Breast Cancer AJCC v6 and v7|Stage IIA Breast Cancer AJCC v6 and v7|Stage IIB Breast Cancer AJCC v6 and v7
Interventions: OTHER: Laboratory Biomarker Analysis|RADIATION: Partial Breast Irradiation|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Combination of Anti-Cancer Drugs Talazoparib and Temozolomide in Patients With Advanced Stage Rare Cancers, RARE 2 Trial
Status: RECRUITING
Conditions: Adrenal Gland Pheochromocytoma|Hematopoietic and Lymphatic System Neoplasm|Malignant Solid Neoplasm|Paraganglioma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Talazoparib|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guided Bone Regeneration of Peri-implant Defects Comparing Submerged Versus Non-submerged Healing
Status: UNKNOWN
Conditions: Peri-Implantitis
Interventions: PROCEDURE: Submerged healing|PROCEDURE: Non-submerged healing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tucaresol As Add-On To HAART (Highly Active Antiretroviral Therapy) In Chronic HIV-1 Infected Adults
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Tucaresol tablets 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nasal Carbon Dioxide (CO2) in the Treatment of Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Nasal CO2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Measles-Mumps-Rubella-Varicella (MMRV) Vaccine, Priorix-Tetra™ in Children Living in the Philippines
Status: WITHDRAWN
Conditions: Mumps|Rubella|Measles|Varicella
Interventions: BIOLOGICAL: Priorix-Tetra™|OTHER: Safety data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Extent to Which the Drug Given as Two Different Capsule Sizes Becomes Available to the Body
Status: COMPLETED
Conditions: Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men
Interventions: DRUG: Elinzanetant (BAY3427080) treatment A|DRUG: Elinzanetant (BAY3427080) treatment B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pembrolizumab (MK-3475) as Maintainance in Treated Patients With Unresectable Stage III NSCLC
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer Patients
Interventions: DRUG: Pembrolizumab Injectable Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TMC278-TiDP15-C150: Trial to Examine Safety, Tolerability and Plasma Pharmacokinetics of Multiple Doses of TMC278LA.
Status: TERMINATED
Conditions: HIV-1
Interventions: DRUG: TMC278
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2
Status: RECRUITING
Conditions: Gastric Cancer|Gastroesophageal Junction Cancer|Pancreatic Adenocarcinoma
Interventions: DRUG: AZD0901|DRUG: 5-Fluorouracil|DRUG: Leucovorin|DRUG: l-leucovorin|DRUG: Irinotecan|DRUG: Nanoliposomal Irinotecan|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The AMPK Modulator Metformin as a Novel Adjunct to Conventional Therapy in Patients With Knee Osteoarthritis
Status: RECRUITING
Conditions: Osteo Arthritis Knee
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single-Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ONO-2952 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Adult Subjects
Interventions: DRUG: ONO-2952|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Wound Interdisciplinary Teams (WIT): A Community- Based Pragmatic Randomized Controlled Trial
Status: COMPLETED
Conditions: Wound of Skin
Interventions: OTHER: Systematic referral to MDWCT and comprehensive primary care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Topical Intranasal Tranexamic Acid for Epistaxis in the Emergency Department
Status: TERMINATED
Conditions: Epistaxis
Interventions: DRUG: Tranexamic Acid|DRUG: 0.9% Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravascular Ultrasound in Patients With End-stage Renal Disease on Dialysis
Status: RECRUITING
Conditions: End Stage Renal Disease
Interventions: DIAGNOSTIC_TEST: Venography|DIAGNOSTIC_TEST: Intravascular ultrasound (IVUS)|OTHER: Image processing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Anesthetic Efficacy of Intrauterine Lidocaine for Removal of a "Lost" Intrauterine Device
Status: COMPLETED
Conditions: "Lost" IUD
Interventions: DRUG: Lidocaine (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Low (30ml) Versus Full Dose (100ml) Contrast CT Pulmonary Angiography in Detecting Emboli
Status: WITHDRAWN
Conditions: Multiple Pulmonary Emboli
Interventions: PROCEDURE: Low-Dose IV Contrast|DEVICE: Siemens Sensation 64-MDCT scanner.|DRUG: Visipaque 320 non-ionic isoosmolar contrast agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Diaphragmatic Resistance Training in People With Chronic Neck Pain.
Status: RECRUITING
Conditions: Neck Pain|Diaphragm|Exercise Training|Inhalation
Interventions: OTHER: Diaphragmatic resistance training|OTHER: Cervical stabilization exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Internet Therapeutic Intervention on A1C Levels in Type 2 Diabetes Mellitus (DM) on Combination Oral Therapy
Status: SUSPENDED
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: Internet Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I/II Trial for Intravitreous Treatment of Severe Ocular Von Hippel-Lindau Disease Using a Combination of the PDGF Antagonist E10030 and the VEGF Antagonist Ranibizumab
Status: COMPLETED
Conditions: Von Hippel-Lindau Syndrome
Interventions: DRUG: Ranibizumab|DRUG: E10030
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Oral Probiotics to Reduce Urinary Oxalate Excretion
Status: COMPLETED
Conditions: Nephrolithiasis|Hyperoxaluria|Crohn's Disease
Interventions: DIETARY_SUPPLEMENT: Oxadrop|DIETARY_SUPPLEMENT: Agri-King Synbiotic (AKSB)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis T Cells Response for Identification of Aspergillus Bronchitis With Cystic Fibrosis Patients
Status: TERMINATED
Conditions: Cystic Fibrosis Patient|Patient Without Treatment Against A.Fumigatus
Interventions: OTHER: T specific response for diagnostic of aspergillus bronchitis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study of Suction as a Mechanism of IUD Expulsion With Concomitant Menstrual Cup Use
Status: RECRUITING
Conditions: IUD; Complications, Mechanical|Menstrual Cup
Interventions: OTHER: Menstrual Cup Removal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MILESTONE - MobILe and tEchnological SoluTions for OccupatioNal drivErs
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: BEHAVIORAL: Real-time triggers|BEHAVIORAL: Personalized tailored feedback|BEHAVIORAL: Real-time triggers + Personalized tailored feedback|BEHAVIORAL: App-supported exercise therapy|BEHAVIORAL: Conventional intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation Of Three Dose Levels Of 3-Antigen Staphylococcus Aureus Vaccine (SA3Ag) In Healthy Adults
Status: COMPLETED
Conditions: Bacterial Infections|Staphylococcal Vaccines|Immunotherapy, Active|Staphylococcal Skin Infections|Staphylococcal Infections
Interventions: BIOLOGICAL: SA3Ag vaccine|PROCEDURE: Blood draw|PROCEDURE: Colonization swab samples|BIOLOGICAL: SA3Ag followed by Placebo|PROCEDURE: Blood draw|PROCEDURE: Colonization swab samples|BIOLOGICAL: Placebo|PROCEDURE: Blood draw|PROCEDURE: Colonization swab samples|BIOLOGICAL: SA3Ag with no booster in stage 2|PROCEDURE: Blood draw|PROCEDURE: Colonization swab samples|PROCEDURE: Placebo with no booster in stage 2|PROCEDURE: Blood draw|PROCEDURE: Colonization swab samples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Multicentre, Parallel Arm, Open-label Trial of Frontline R-CHOP/Pola-RCHP and Glofitamab in Younger, Higher Risk Patients With Diffuse Large B Cell Lymphoma (DLBCL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B Cell Lymphoma|High-grade B-cell Lymphoma
Interventions: DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisolone|DRUG: Glofitamab|DRUG: Polatuzumab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Paclitaxel Eluting Stent vs Paclitaxel Eluting Balloon Treating Peripheral Artery Disease of the Femoral Artery
Status: COMPLETED
Conditions: Peripheral Artery Disease
Interventions: DEVICE: Paclitaxel Eluting Stent|DEVICE: Paclitaxel Eluting Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Human Biodistribution and Dosimetry of the Radionuclide Labeled ZT-111 in Patients With Metastatic Prostate Cancer
Status: RECRUITING
Conditions: Prostate Specific Membrane Antigen Positive Metastatic Prostate Cancer
Interventions: RADIATION: [131I]/[18F]/[68Ga]ZT-111
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC