pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: RO4929097 in Children With Relapsed/Refractory Solid or CNS Tumors, Lymphoma, or T-Cell Leukemia
Status: WITHDRAWN
Conditions: Lymphoma|Brain Neoplasms|Sarcoma|Osteosarcoma|Wilm's Tumor
Interventions: DRUG: RO4929097|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing E-liquid Product Standards (Sweet Spot Study)
Status: RECRUITING
Conditions: Nicotine|Nicotine Vaping|E-cigarette Use
Interventions: BEHAVIORAL: Vaping study EC A|BEHAVIORAL: Vaping study EC B|BEHAVIORAL: Vaping study EC C|BEHAVIORAL: Vaping study EC D|BEHAVIORAL: Vaping study EC E|BEHAVIORAL: Vaping study EC F|BEHAVIORAL: Vaping study EC G|BEHAVIORAL: Vaping study EC H|BEHAVIORAL: Vaping study EC I|BEHAVIORAL: Vaping study EC J
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Switching Drug Therapy for the Prevention of Blood Clot Formation From Enoxaparin to Rivaroxaban After Orthopedic Surgery for Either Total Hip or Total Knee Replacement
Status: COMPLETED
Conditions: Arthritis|Osteoarthritis, Knee|Osteoarthritis, Hip|Thromboembolism
Interventions: DRUG: Rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Seroma at the Donor Site of the TRAM Flap, With or Without Quilting Suture: A Comparative Study Using Ultrasound
Status: COMPLETED
Conditions: Seroma
Interventions: PROCEDURE: quilting suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Intensive Lipid Lowering and Omega-3 Fatty Acid on Composition of Coronary Atherosclerotic Plaque
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Intensive lipid lowering plus Omega3-fatty acid|DRUG: Moderate lipid lowering plus Omega3-fatty acid|DRUG: Intensive lipid lowering plus placebo|DRUG: Moderate lipid lowering plus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of Oxandrolone Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: To Determine the Bioequivalence Under Fasting Conditions
Interventions: DRUG: Oxandrolone|DRUG: Oxandrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Gene Polymorphisms Influencing Steroid Synthesis and Action
Status: WITHDRAWN
Conditions: Disorders of Sex Development|Congenital Adrenal Hyperplasia|Congenital Adrenal Hypoplasia|Adrenal Insufficiency|Mineralocorticoid Deficiency|Intersex
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of TwHF in HIV Patients With Poor Immune Responses
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Tripterygium Wilfordii Hook F extract (TwHF extract)|DRUG: cART
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: iLink (Incentives for Linkage to ART) Study: A Mixed-methods Study to Improve Linkage to HIV Care
Status: UNKNOWN
Conditions: HIV
Interventions: BEHAVIORAL: Conditional economic incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study To Assess Growth In Children With Seasonal Allergic And/Or Perennial Allergic Rhinitis Treated With GW685698X Aqueous Nasal Spray Or Placebo Nasal Spray
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial and Seasonal
Interventions: DRUG: GW685698X
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy of Two Oral Rehydration Solutions, With or Without the Probiotic Lactobacillus Reuteri DSM 17938 and Zinc, on the Duration and Severity of Acute Gastroenteritis in 6 - 36 Months Old Children in Out-patient Care
Status: TERMINATED
Conditions: Acute Gastroenteritis
Interventions: DIETARY_SUPPLEMENT: Lactobacillus reuteri DSM 17938 and zinc sulphate|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of Jian Pi Yi Shen Hua Tan Granules in Cognitive Impairment After Acute Cerebral Infarction
Status: COMPLETED
Conditions: Cognitive Impairment
Interventions: DRUG: Jian Pi Yi Shen Hua Tan Granules|OTHER: the placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Use of a Probiotic in the Treatment of Fibromyalgia (FIBROPROB)
Status: UNKNOWN
Conditions: Fibromyalgia
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Stage IIB, Stage III, or Stage IV Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: HER-2-neu, CEA peptides, GM-CSF, Montanide ISA-51 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Carbon Dioxide (CO2) to Air Insufflation in Colonoscopy in Patients With Inflammatory Bowel Disease
Status: UNKNOWN
Conditions: Inflammatory Bowel Diseases
Interventions: OTHER: carbon dioxide insufflation during colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Diagnostic Study of Lateral Ligament Complex Injury of Ankle
Status: RECRUITING
Conditions: Chronic Instability of Ankle Joint|Lateral Ligament Complex Injury of Ankle
Interventions: DIAGNOSTIC_TEST: Stress radiography,Anterior drawer test,Stress ultrasound,Computed tomography, Magnetic resonance imaging,Arthroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of the ONCOlytic VIRus Armed for Local Chemotherapy, TG6002/5-FC, in Recurrent Glioblastoma Patients
Status: UNKNOWN
Conditions: Glioblastoma|Brain Cancer
Interventions: DRUG: Combination of TG6002 and 5-flucytosine (5-FC, Ancotil®)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Two Concentrations of Bupivacaine in Women in Labor
Status: COMPLETED
Conditions: Obstetric Pain
Interventions: DRUG: bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Frequency-altering AKE-1 Capsule and Pillcam SB2
Status: COMPLETED
Conditions: Intestinal Diseases|Gastrointestinal Hemorrhage
Interventions: DEVICE: AKE-1|DEVICE: Pillcam SB2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Serum Calprotectin Level in Patients With Rheumatoid Arthritis and Osteoarthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis and Osteoarthritis
Interventions: OTHER: serum calprotectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase 3b Randomized, Double-blind, Multi-center Study to Compare the Safety and Efficacy of Omadacycline to Moxifloxacin for Treating Adult Subjects With CABP
Status: RECRUITING
Conditions: Community-acquired Bacterial Pneumonia
Interventions: DRUG: Omadacycline|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Safety, Tolerability and Efficacy of AZD5363 When Combined With Paclitaxel in Breast Cancer Patients
Status: COMPLETED
Conditions: Advanced or Metastatic Breast Cancer|ER+ve Advanced or Metastatic Breast Cancer
Interventions: DRUG: AZD5363 when combined with weekly paclitaxel.|DRUG: AZD5363 when combined with weekly paclitaxel.|DRUG: AZD5363when combined with weekly paclitaxel.|DRUG: A placebo in combination with weekly paclitaxel.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective RSA and Clinical Evaluation of the Trident II Acetabular Cup
Status: UNKNOWN
Conditions: Total Hip Arthroplasty|Acetabular Cup
Interventions: RADIATION: Radiostereometric Analysis|PROCEDURE: total hip arthroplasty with RSA bead implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase I/II Study of COVID-19 DNA Vaccine (AG0302-COVID19 High-dose)
Status: COMPLETED
Conditions: COVID-19 Lower Respiratory Infection
Interventions: BIOLOGICAL: AG0302-COVID19 for Intramuscular Injection|BIOLOGICAL: AG0302-COVID19 for Intramuscular Injection|BIOLOGICAL: AG0302-COVID19 for Intramuscular Injection|BIOLOGICAL: AG0302-COVID19 for Intradermal Injection|BIOLOGICAL: AG0302-COVID19 for Intradermal Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Studying Health Outcomes After Treatment in Patients With Retinoblastoma
Status: RECRUITING
Conditions: Retinoblastoma|Cancer Survivor|Biological Sibling|Intraocular Retinoblastoma|Unilateral Retinoblastoma
Interventions: PROCEDURE: Biospecimen collection|OTHER: Vision assessment|OTHER: Questionnaire administration|OTHER: Quality of life assessment|OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of a Stress Management Program on Occupational Stress and Coping Strategies Among Nurses
Status: COMPLETED
Conditions: Occupational Stress|Coping Skills
Interventions: OTHER: Stress management program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TDCS to Improve Motivation and Memory in Elderly (TIME)
Status: UNKNOWN
Conditions: Motivation
Interventions: DEVICE: Direct tDCS|DEVICE: Indirect tDCS|DEVICE: Personalized tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Drug Therapy for Generalized Anxiety Disorder Among the Elderly
Status: COMPLETED
Conditions: Anxiety Disorders|Generalized Anxiety Disorder
Interventions: DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OsteoStrux™ Collagen Ceramic Scaffold in Instrumented Lumbar Spine Fusion
Status: COMPLETED
Conditions: Degenerative Changes|Stenosis|Spondylosis
Interventions: PROCEDURE: Posterolateral Fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dendritic Cell Vaccination With Standard Postoperative Chemoradiation for the Treatment of Adult Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma
Interventions: BIOLOGICAL: TH-1 Dendritic Cell Immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Immune Response of Five Admixtures of a Tetravalent Dengue Virus Vaccine
Status: COMPLETED
Conditions: Dengue
Interventions: BIOLOGICAL: TetraVax-DV Vaccine-Admixture 1|BIOLOGICAL: TetraVax-DV Vaccine-Admixture 2|BIOLOGICAL: TetraVax-DV Vaccine-Admixture 3|BIOLOGICAL: TetraVax-DV Vaccine-Admixture 4|BIOLOGICAL: Placebo|BIOLOGICAL: TetraVax-DV Vaccine-Admixture 5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Covid-19 Infection and Pulmonary Distress Treatment With Zanubrutinib in Hospitalized Participants
Status: COMPLETED
Conditions: COVID-19 Pulmonary Complications|COVID-19
Interventions: DRUG: Zanubrutinib|DRUG: Supportive Care|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Therapy(3 vs. 6 Months) With the FOLFOX 4 or XELOX for Stage II or Stage III Colon Cancer
Status: UNKNOWN
Conditions: CRC
Interventions: DRUG: 5-Fluorouracil|DRUG: Leucovorin|DRUG: Oxaliplatin|DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: 5-Fluorouracil|DRUG: Leucovorin|DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventive PCI or Medical Therapy Alone for Vulnerable Atherosclerotic Coronary Plaque
Status: COMPLETED
Conditions: Coronary Artery Disease|Plaque, Atherosclerotic
Interventions: DEVICE: Coronary intervention|DRUG: Optimal Medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of OCP and Metformin on Clinical, Hormonal, Metabolic and Ultrasonographic Characteristics in PCOS
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Metformin|DRUG: ethinyl estradiol and cyproterone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bintrafusp Alfa Before Surgery for the Treatment of Untreated Resectable Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Resectable Lung Non-Small Cell Carcinoma|Stage I Lung Cancer AJCC v8|Stage IA1 Lung Cancer AJCC v8|Stage IA2 Lung Cancer AJCC v8|Stage IA3 Lung Cancer AJCC v8|Stage IB Lung Cancer AJCC v8|Stage II Lung Cancer AJCC v8|Stage IIA Lung Cancer AJCC v8|Stage IIB Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8
Interventions: DRUG: Bintrafusp Alfa|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Non-nutritive Sweeteners on the Composition of the Gut Microbiome
Status: COMPLETED
Conditions: Obesity|Diabetes
Interventions: OTHER: commercially-available diet soda|OTHER: carbonated water (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study Evaluating Oral MOA-728 For The Treatment Of OIBD In Subjects With Chronic Non-Malignant Pain
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: N-methylnaltrexone bromide (MOA-728)|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ex-vivo Adhesion of Bacteria to Different Contact Lens Materials
Status: WITHDRAWN
Conditions: Visual Acuity
Interventions: DEVICE: 1-DAY ACUVUE MOIST|DEVICE: DAILIES AQUA COMFORT PLUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Neuromuscular Pelvic Realigning Exercises on Pelvic Floor Muscle Function in Continent SubjectS
Status: UNKNOWN
Conditions: Pelvic Floor Muscle Weakness|Stress Urinary Incontinence|Pelvic Asymmetry
Interventions: OTHER: neuromuscual realigning exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Cesarean Section Scar Defect (Niche) Affect Implantation Rate?
Status: UNKNOWN
Conditions: Infertility|Complications; Cesarean Section
Interventions: PROCEDURE: hysteroscopic repair of cesarean section defect|PROCEDURE: Diagnostic Hysteroscopy|PROCEDURE: Ultrasound Scan|PROCEDURE: IVF Cycle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ERAS Swallowing Rehabilitation in Elder Patients
Status: NOT_YET_RECRUITING
Conditions: The Upper Esophageal Sphincter Contraction Strength
Interventions: BEHAVIORAL: early rehabiliation swallowing program|BEHAVIORAL: not receiving early rehabilitation swallowing program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bone Healing After Dental Extraction in Postmenopausal Osteoporotic Women Treated With Alendronate Per os Weekly
Status: COMPLETED
Conditions: Alveolar Bone Healing After Dental Extraction
Interventions: PROCEDURE: Dental extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Efficacy and Safety of RTX-GRT7039 in Adult Subjects With Knee Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis
Interventions: DRUG: RTX-GRT7039|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Desflurane vs. Sevoflurane in Endovascular Aortic Repair
Status: COMPLETED
Conditions: Renal Failure
Interventions: DRUG: Sevoflurane|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Hypertension And Surgery Study: Evaluating the Implementation of a Hypertension Guideline Protocol
Status: COMPLETED
Conditions: Hypertension|Metabolic Syndrome|Non-Compliance, Medication
Interventions: DRUG: Antihypertensive medication according to the study's algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Tablet Size on Cognitive Performance Caffeine
Status: COMPLETED
Conditions: Placebo Effect
Interventions: DRUG: Caffeine Anhydrous with small sucrose pill|OTHER: Placebo - large sucrose pill|DRUG: Caffeine Anhydrous with large sucrose pill|OTHER: Placebo - small sucrose pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Interaction Between Reboxetine and 3,4-Methylenedioxymethamphetamine: Pharmacodynamics (PD) and Pharmacokinetics (PK)
Status: COMPLETED
Conditions: Mood Disorder|Substance-related Disorders|Amphetamine-related Disorders
Interventions: DRUG: MDMA|DRUG: Reboxetine, 8 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy Study of CC-486 With MK-3475 to Treat Locally Advanced or Metastatic Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: CC-486|DRUG: Pembrolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pain Neuroscience Education Using an Infographic in Basketball Elite Athletes
Status: COMPLETED
Conditions: Elite Basketball Athletes
Interventions: BEHAVIORAL: Infographic|BEHAVIORAL: Powerpoint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Canadian Men and Pre/Peri/Post-menopausal Women With ER+ Advanced Breast Cancer in the Real-World Setting With Hormone Therapy ± Targeted Therapy
Status: COMPLETED
Conditions: HR+ HER2- Men, Pre/Postmenopausal Advanced Breast Cancer
Interventions: DRUG: Endocrine therapy may include one of the following therapies: letrozole, anastrozole, exemestane, tamoxifen or fulvestrant|DRUG: Endocrine therapy in combination with targeted therapy may include: everolimus plus exemestane or CDK4/6 inhibitor plus endocrine therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prefabricated Versus 3D-Printing Myofunctional Appliances
Status: UNKNOWN
Conditions: Class II Division 1 Malocclusion
Interventions: PROCEDURE: 3d-Printing Myofunctional Appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Effect of Panfoxol of Otolaryngological Diseases of Upper Respiratory Tract Infection: A Multicenter Retrospective Observational Study
Status: COMPLETED
Conditions: Otologic Disease
Interventions: DRUG: Panfoshu+Conventional Treatment（program-A）|DRUG: Panfoshu+Conventional Treatment（program-B）|OTHER: Conventional Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin A in Patients With Myofascial Pain Syndrome With and Without Zinc Supplementation
Status: ENROLLING_BY_INVITATION
Conditions: Myofacial Pain Syndrome|Botulinum Toxin
Interventions: DRUG: Solvazinc 50mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Oral Zinc Administration as an Adjunct Therapy in New Pulmonary Tuberculosis (Category I) Patients
Status: UNKNOWN
Conditions: Pulmonary Tuberculosis
Interventions: DIETARY_SUPPLEMENT: Zinc supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Short-Term Outcome of N-Carbamylglutamate in the Treatment of Acute Hyperammonemia
Status: COMPLETED
Conditions: Propionic Acidemia, Type I and/or Type II|Methylmalonic Acidemia|Carbamoyl-Phosphate Synthase I Deficiency Disease|Ornithine Carbamoyltransferase Deficiency
Interventions: DRUG: Carbaglu|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application of Ectoin Containing Lozenges (EHT02) in Patients With Acute, Viral Pharyngitis.
Status: COMPLETED
Conditions: Acute Viral Pharyngitis
Interventions: DEVICE: Ectoin Lozenges Honey Lemon|DEVICE: Hyaluronic Acid/Icelandic moss Lozenges
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reducing Opioid Use for Chronic Pain Patients Following Surgery
Status: RECRUITING
Conditions: Chronic Pain|Opioid Use|Postoperative Pain|Opioid Dependence
Interventions: OTHER: Interventional Group|OTHER: Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of the Consumption of a Food Supplement in a Group of Healthy People
Status: COMPLETED
Conditions: Immune System and Related Disorders
Interventions: DIETARY_SUPPLEMENT: Dietary supplementation with capsules containing rosemary and alkylglycerol|DIETARY_SUPPLEMENT: Dietary supplementation with control capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive-Behavioural and Hypnotic Treatment of Chronic Primary Insomnia Among the Elderly
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: Cognitive behavior therapy (CBT)|DRUG: Zopiclone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Multicomponent Intervention to Decrease Chronic Obstructive Pulmonary Disease (COPD)-Related Hospitalizations
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: BEHAVIORAL: Self-Management and Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of PegIFN +/- FTC / TDF to Treat Chronic Hepatitis B in HIV-Coinfected Patients
Status: TERMINATED
Conditions: Chronic Hepatitis B|HIV Infections
Interventions: DRUG: pegylated interferon alfa-2a|DRUG: tenofovir DF / emtricitabine combination therapy|DRUG: pegIFN / TDF / FTC combination therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vegan or Animal Protein Ingestion on the Recovery of Muscle Function Following Exercise
Status: COMPLETED
Conditions: Muscle Recovery
Interventions: DIETARY_SUPPLEMENT: Recovery animal (20g whey) protein supplement|DIETARY_SUPPLEMENT: Recover vegan (26g pea) protein supplement|DIETARY_SUPPLEMENT: Placebo (32g maltodextrin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Randomized Study Comparing Two Models of a Travoprost Intraocular Implant to Timolol Maleate Ophthalmic Solution, 0.5%
Status: ACTIVE_NOT_RECRUITING
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: COMBINATION_PRODUCT: G2-TR intraocular implant containing travoprost|DRUG: Sham surgery + active-comparator eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Laser in Root Canal Disinfection
Status: COMPLETED
Conditions: Pulp and Periapical Tissue Disease|Pulp Necroses|Pulp; Granuloma
Interventions: COMBINATION_PRODUCT: Conventional group (NaOCl/EDTA)|COMBINATION_PRODUCT: Dual laser group (Er,Cr:YSGG/Diode):|COMBINATION_PRODUCT: Combined group (EDTA/Diode):
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunopheresis Alone or in Combination With Paclitaxel or Atezolizumab in Non-small Cell Lung Cancer (NSCLC).
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DEVICE: LW-02 device immunopheresis combined with atezolizumab|DEVICE: LW-02 device immunopheresis combined with weekly paclitaxel|DEVICE: LW-02 device immunopheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Clinical Study of Treatment With Disitamb Vedotin Plus Pyrotinib in HER2-positive Early Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Disitamb Vedotin ,pyrotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thin Endometrium Undergoing Frozen-thawed Embryo Transfer
Status: UNKNOWN
Conditions: Thin Endometrium
Interventions: DRUG: Tamoxifen and femoston|DRUG: Vitamin C and femoston
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: SPYRAL DYSTAL Renal Denervation Global Clinical Study
Status: COMPLETED
Conditions: Hypertension|Vascular Diseases|Cardiovascular Diseases
Interventions: DEVICE: Renal Denervation (Symplicity Spyral™)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Antiepileptic Drug Effects on Child Development
Status: COMPLETED
Conditions: Epilepsy
Interventions: PROCEDURE: TONI-3|PROCEDURE: WRAT-3|PROCEDURE: Connor's Rating Scales PRS & TRS|PROCEDURE: Peabody Picture Vocabulary Test|PROCEDURE: Children's Memory Scale|PROCEDURE: WISC-3|PROCEDURE: Behavioral Assessment System for Children PRS & TRS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 68Ga-BMV101 PET/CT in Patients With Idiopathic Pulmonary Fibrosis
Status: UNKNOWN
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: 68Ga-BMV101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Glioma Adaptive Radiotherapy With Development of an Artificial Intelligence Workflow
Status: NOT_YET_RECRUITING
Conditions: Diffuse Glioma|Glioblastoma|Adaptive Radiotherapy|Artificial Intelligence
Interventions: RADIATION: Adaptive radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monitoring of Oral Human Papillomavirus Infection (HPV) in HPV-positive Oropharyngeal Squamous Cell Carcinoma (OPSCC)
Status: TERMINATED
Conditions: Carcinoma, Squamous Cell|Head and Neck Neoplasms|Oropharyngeal Neoplasms
Interventions: OTHER: Assessment of Oral HPV Infection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Auditory Beat Stimulation and Behavioural Variant of Frontotemporal Dementia
Status: COMPLETED
Conditions: Anxiety|bvFTD
Interventions: OTHER: Auditory beat stimulation: 8Hz monaural beat stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vitality: Promoting Cognitive Function in Older Adults With Chronic Stroke
Status: COMPLETED
Conditions: Stroke|Chronic Stroke
Interventions: BEHAVIORAL: Exercise training|BEHAVIORAL: Complex mental and social activities|BEHAVIORAL: Control: stretching and relaxation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interstitial Photodynamic Therapy (PDT) With Temoporfin for Advanced Head and Neck Cancers
Status: TERMINATED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Temoporfin|DEVICE: Medical diode laser emitting light at a wavelength of 652 nm. (Ceralas PDT 652, CeramOptec GmbH)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Determining the Clinical Class of Chronic Venous Disorders by Artificial Intelligence
Status: RECRUITING
Conditions: Varicose Veins of Lower Limb|Telangiectasia
Interventions: DIAGNOSTIC_TEST: Determining of the clinical class of chronic venous disorders by artificial intelligence
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Gemcitabine, Nab-paclitaxel, Durvalumab, and Oleclumab Before Surgery for the Treatment of in Resectable/Borderline Resectable Primary Pancreatic Cancer
Status: RECRUITING
Conditions: Borderline Resectable Pancreatic Adenocarcinoma|Resectable Pancreatic Adenocarcinoma|Stage IA Pancreatic Cancer AJCC v8|Stage IB Pancreatic Cancer AJCC v8|Stage IIA Pancreatic Cancer AJCC v8|Stage IIB Pancreatic Cancer AJCC v8
Interventions: BIOLOGICAL: Durvalumab|DRUG: Gemcitabine|DRUG: Nab-paclitaxel|BIOLOGICAL: Oleclumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fludarabine and Cytarabine Versus High-dose Cytarabine for CBF-AML
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|Core-Binding Factor
Interventions: DRUG: Fludarabine|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of STRO-002, an Anti-Folate Receptor Alpha (FolRα) Antibody Drug Conjugate in Ovarian & Endometrial Cancers
Status: COMPLETED
Conditions: Ovarian Cancer|Ovarian Carcinoma|Ovary Cancer|Endometrial Cancer|Endometrioid Adenocarcinoma|Fallopian Tube Cancer|Primary Peritoneal Carcinoma
Interventions: DRUG: STRO-002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QUILT 2.023: A Study of N-803 in Combination With Current Standard of Care vs Standard of Care as First-Line Treatment for Patients With Stage 3 or 4 NSCLC.
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: N-803 + Pembrolizumab|DRUG: N-803 + Carboplatin + Nab-paclitaxel + Pembrolizumab|DRUG: N-803 + Cisplatin or Carboplatin + Pembrolizumab + Pemetrexed|DRUG: Pembrolizumab|DRUG: Carboplatin + Nab-paclitaxel or Paclitaxel + Pembrolizumab|DRUG: Cisplatin or Carboplatin + Pembrolizumab + Pemetrexed|DRUG: N-803 + Carboplatin + Nab-paclitaxel + Ipilimumab + Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of a 12 Week Home-based Exercise Intervention on Physical Performance in Patients With Cancers of the Gastrointestinal Tract With Pre- Cachexia or Cachexia
Status: COMPLETED
Conditions: Cachexia|Weight Loss|Gastrointestinal Cancer
Interventions: OTHER: EXCAP©®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of Dutogliptin in Subjects With Type 2 Diabetes Mellitus on a Background Medication of Metformin
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: dutogliptin|DRUG: sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Individualized Alpha Neurofeedback for ADHD
Status: RECRUITING
Conditions: ADHD
Interventions: BEHAVIORAL: attenuating individualized lower alpha neurofeedback|BEHAVIORAL: Sham neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Barrier Function and Production of Inflammatory Cytokines in the Rectal Mucosa in Patients With Septic Shock
Status: UNKNOWN
Conditions: Septic Shock
Interventions: PROCEDURE: Rectal biopsy|PROCEDURE: Measurement of inflammatory markers in the rectal mucosa|PROCEDURE: Measurement of rectal lactic acid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Metformin for Treatment of Cytopenia in Children and Adolescents With Fanconi Anemia
Status: RECRUITING
Conditions: Fanconi Anemia
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mindfulness-based Intervention to Promote Psychological Wellbeing in People With Epilepsy
Status: COMPLETED
Conditions: Epilepsy|Brain Diseases|Central Nervous System Diseases|Nervous System Diseases
Interventions: BEHAVIORAL: Mindfulness-based therapy|BEHAVIORAL: No-intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Cross Over Trial of Two Treatments for Obstructive Sleep Apnea in Veterans With Post Traumatic Stress Disorder
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: CPAP versus MAD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Electromagnetic Field and Noise on Resting Electroencephalogram of Health Subjects
Status: COMPLETED
Conditions: Electroencephalography|Electromagnetic|Noise Exposure
Interventions: OTHER: noise expose|OTHER: RF expose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Is Physical Therapy Clearance Before Arthroplasty Home Discharge Necessary?
Status: NOT_YET_RECRUITING
Conditions: Physical Therapy|Total Joint Arthroplasty|Same-day Discharge
Interventions: OTHER: Novel same-day discharge protocol after total joint arthroplasty|OTHER: Conventional postoperative physical therapy clearance
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Lecithin-based Curcuma and Boswellia on Post-acute COVID-19 IBS
Status: COMPLETED
Conditions: Post-Acute COVID-19 Syndrome|Irritable Bowel Syndrome|Abdominal Pain|Dysbiosis
Interventions: DIETARY_SUPPLEMENT: Curcuma longa and Boswellia serrata extracts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplemental Nicotine Administration for Smoking Cessation in Posttraumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: nicotine patch|DRUG: placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of PD-L1 Antibody ZKAB001 Combined With Capecitabine in Resected Biliary Tract Cancer
Status: UNKNOWN
Conditions: Biliary Tract Cancer
Interventions: DRUG: ZKAB001 5mg/kg|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Polycystic Ovary Syndrome on Pelvic Floor Structure and Function
Status: COMPLETED
Conditions: Reproductive System Disorder|Urinary Incontinence|Urogenital Disease|Polycystic Ovary Syndrome
Interventions: DIAGNOSTIC_TEST: Anogenital distance measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Visual and Refractive Outcomes of The ClarVista HARMONI™ Modular Intraocular Lens System (HMIOL)
Status: COMPLETED
Conditions: Cataract|Aphakia
Interventions: DEVICE: Harmoni Modular Intraocular Lens|PROCEDURE: Optic Exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Weight Reduction on Immunity
Status: COMPLETED
Conditions: Lymphocytes|Weight Loss|Viral Diseases|Immunity|Anti-obesity Agents
Interventions: COMBINATION_PRODUCT: weight loss program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of IMB-101 in Healthy Volunteers and Participants With Rheumatoid Arthritis
Status: NOT_YET_RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: IMB-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Pilot Study of [Ga-68]PSMA PET/MRI for the Assessment of PSMA-positive Tumors
Status: COMPLETED
Conditions: Prostate-specific Membrane Antigen Positive Tumors|Prostate Cancer|Breast Cancer|Lung Cancer
Interventions: DEVICE: [Ga-68]PSMA PET/MR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tart Cherry and Omega-3's for Aromatase Inhibitor Musculoskeletal Symptoms
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS)|Joint Pain
Interventions: DIETARY_SUPPLEMENT: Tart Cherry|DIETARY_SUPPLEMENT: Omega 3 FA (Fish Oil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Tongluo-Kaibi Tablet in Patients With Fibromyalgia Syndrome
Status: NOT_YET_RECRUITING
Conditions: Fibromyalgia Syndrome
Interventions: DRUG: Tongluo-Kaibi tablet plus placebo of pregabalin|DRUG: placebo of Tongluo-Kaibi tablet plus pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Evaluate Safety, Tolerability and Pharmacokinetics of ONO-4053 in Healthy Volunteers
Status: TERMINATED
Conditions: Healthy Adult Subjects
Interventions: DRUG: ONO-4053|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Therapy Intervention in Dental Students
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain|Strength|Quality of Life
Interventions: PROCEDURE: Supervised exercise + home exercise program|PROCEDURE: Home exercise program only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of YL202 in Selected Patients With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: NSCLC|Breast Cancer|HNSCC|Locally Advanced or Metastatic Solid Tumors
Interventions: DRUG: YL202 should be intravenously infused
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: [18F] Dihydro-testosterone Pet and MR Imaging In Patients With Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Localized Prostate Cancer
Interventions: DRUG: [18F] DIHYDRO-TESTOSTERONE|DEVICE: PET scan|DEVICE: MRI|OTHER: Blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparing Harmonic Ultrasonic Scalpel to Small Jaw Bipolar Device in Thyroid Surgery
Status: COMPLETED
Conditions: Thyroid Diseases
Interventions: DEVICE: Harmonic Scalpel (Ethicon Endo-Surgery, USA)|DEVICE: Ligasure Small Jaw (Covidien, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Task Oriented Intervention With Two Goal-setting Approaches
Status: COMPLETED
Conditions: Movement Disorder|Learning Disability|Autism Spectrum Disorder|Children
Interventions: BEHAVIORAL: child-goal|BEHAVIORAL: parent-goal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-dose Opioid Versus Opioid-sparing Anaesthesia in Cardiac Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Cardiac Surgery Patients
Interventions: OTHER: opioid-sparing protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ultra-low Dose Naloxone During Supraclavicular Brachial Plexus Block on Post-operative Opioi
Status: COMPLETED
Conditions: Upper Extremity Trauma
Interventions: DRUG: Bupivacaine plus naloxone|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Assess the Efficacy and Long-term Safety of Dupilumab (REGN668/SAR231893) in Adult Participants With Moderate-to-Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Dupilumab|DRUG: Placebo (for Dupilumab)|OTHER: Topical Corticosteroid (TCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antegrade Cerebral Perfusion and Retrograde Inferior Vena Caval Perfusion for Total Aortic Arch Replacement
Status: UNKNOWN
Conditions: Type A Aortic Dissection|Circulatory Arrest|Hypothermia
Interventions: PROCEDURE: Retrograde Inferior Vena Caval Perfusion|PROCEDURE: Select antegrade cerebral perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carboplatin, Paclitaxel With or Without Avelumab in Advanced or Recurrent Endometrial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Cancer
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Safety, Tolerability, and Immunogenicity of A Multivalent Group B Streptococcus Vaccine When Administered Concomitantly With Tdap in Healthy Nonpregnant Women
Status: COMPLETED
Conditions: Group B Streptococcus Infections
Interventions: BIOLOGICAL: Multivalent Group B streptococcus vaccine|BIOLOGICAL: Tetanus, diphtheria, and acellular pertussis vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Exercise for Improving Long-course Chemoradiotherapy Efficacy in People With Locally Advanced Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Rectal Carcinoma
Interventions: OTHER: Supervised Vigorous intensity aerobic interval exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE