pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Healing of Punch Graft Wounds. Comparative Study Between MariGen and Oasis: a Non-inferiority Study
Status: COMPLETED
Conditions: Punch Biopsy Wounds|Healing Times
Interventions: DEVICE: Punch biopsies treated with MariGen Wound ECM dressing|DEVICE: Punch biopsies treated with Oasis ECM dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SCS for Vasospastic Angina Vasospastic Angina Pectoris - a Prospective Study
Status: NOT_YET_RECRUITING
Conditions: Angina Pectoris; Angiospastic
Interventions: DEVICE: Spinal Cord Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of HCQ Plus TPO-RA in ANA Positive ITP
Status: RECRUITING
Conditions: Immune Thrombocytopenia With Positive ANA Antibodies
Interventions: DRUG: Hydroxychloroquine Oral Tablet|DRUG: Eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: WOB and Paediatric Mechanical Ventilation
Status: COMPLETED
Conditions: Pediatric Respiratory Diseases|Ventilator Weaning|Respiration, Artificial|Respiratory Failure|Pediatrics|Work of Breathing
Interventions: PROCEDURE: Sprinting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study to Evaluate B-Lock™ as an Antimicrobial Lock Solution in Dialysis Patients With a CVC
Status: TERMINATED
Conditions: Dialysis Catheter Infections
Interventions: DEVICE: B-Lock|DRUG: Heparin 5,000 U/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Insignia™ Hip Stem Outcomes Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Hip Osteoarthritis|Avascular Necrosis|Rheumatoid Arthritis|Post-traumatic Osteoarthritis|Femoral Neck Fractures|Trochanteric Fractures|Surgery
Interventions: DEVICE: Insignia uncemented Hip Stem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Effects of Different Sized Particles on Cells in the Nose
Status: COMPLETED
Conditions: Hypersensitivity, Immediate|Atopic Hypersensitivity
Interventions: DRUG: Carbon Black|DRUG: Diesel Exhaust Particles|DRUG: Fine Concentrated Ambient Particles|DRUG: Ultrafine Concentrated Ambient Particles|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Efficacy of Luspatercept in ESA-naive LR-MDS Patients With or Without Ring Sideroblasts Who do Not Require Transfusions
Status: RECRUITING
Conditions: Myelodysplastic Syndromes|Anemia
Interventions: DRUG: Luspatercept Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gabapentin in Preventing Nausea and Vomiting in Patients Receiving Chemotherapy
Status: COMPLETED
Conditions: Nausea and Vomiting|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: dexamethasone|DRUG: gabapentin|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing PI-Based to a nNRTI-based ART for Clearance of Plasmodium Falciparum Parasitemia in HIV-Infected
Status: COMPLETED
Conditions: HIV-1 Infection|Pf Subclinical Parasitemia
Interventions: DRUG: Lopinavir/ritonavir|DRUG: Emtricitabine/tenofovir disoproxil fumarate|DRUG: Efavirenz|DRUG: Nevirapine|DRUG: Trimethoprim/sulfamethoxazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Education and Training Competences in Thoracic Ultrasound
Status: UNKNOWN
Conditions: Respiratory Failure|Dyspnea|Pleural Effusion|Pulmonary Edema|Pneumothorax
Interventions: DEVICE: Simulator|DEVICE: Healthy figurants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Three-month Chan-Chung Qigong Improves Physical Function Performance and Quality of Life
Status: COMPLETED
Conditions: Cognitive Dysfunction|Cognitive Aging|Grip|Exercise Training|Physical Endurance|Cognitive Decline
Interventions: PROCEDURE: Chan-Chuang qigong
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Research Studying Interventions for Nighttime Fears in Preschool Children
Status: COMPLETED
Conditions: Nighttime Fears
Interventions: BEHAVIORAL: CBT with parent involved play|BEHAVIORAL: Triadic expressive play therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Evaluate the Drug-Drug Interaction Potential Between ALG-055009 and Statin Therapy(Ies)
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: Atorvastatin|DRUG: ALG-055009|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Emactuzumab and Atezolizumab Administered in Combination in Participants With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Cancers
Interventions: DRUG: Atezolizumab|DRUG: Emactuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Checklists Resuscitation Emergency Department
Status: NOT_YET_RECRUITING
Conditions: Shortness of Breath|Chest Pain|Abdominal Pain|Altered Mental Status|Syncope|Seizures|Vertigo|Trauma|Allergic Reaction|Fever|Cardiac Arrest|Asthma Acute|COPD Exacerbation Acute|Pneumonia|Pulmonary Edema - Acute|Bradycardia|Tachycardia|Shock|Burns|Poisoning|Diabetic Ketoacidosis|Hyperglycemic Hyperosmolar Nonketotic Syndrome
Interventions: OTHER: Emergency Manual
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of Non-invasive Ventilation on the Reperfusion Pulmonary Edema Post Pulmonary Artery Angioplasty in the Post Embolic Pulmonary Hypertension
Status: UNKNOWN
Conditions: Reperfusion Pulmonary Edema
Interventions: OTHER: Blood samples for assays of plasma inflammatory markers (cytokines InterLeukin-6, InterLeukin-8, InterLeukin-10)|PROCEDURE: Non invasive ventilation|PROCEDURE: monitoring system Pulse-Induced Contour Cardiac Output (Picco)|PROCEDURE: Computed tomography (CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Symptom Management in Patients on Dialysis
Status: ACTIVE_NOT_RECRUITING
Conditions: End-stage Kidney Disease
Interventions: OTHER: SUPPORT-DIALYSIS with Access to Output Report and Information Hub|OTHER: SUPPORT-DIALYSIS Only
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: 19 Versus 22-Gauge Needle for EUS-LB
Status: COMPLETED
Conditions: Diagnoses Diseases|Ultrasound Therapy; Complications|Liver Diseases
Interventions: DEVICE: EUS-guided liver biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Two Liquid Oxygen Devices in Deambulation
Status: COMPLETED
Conditions: To Determine the Efficacy of Two Liquid Oxygen Device
Interventions: DEVICE: Oxygen conserving devices|DEVICE: Oxygen conserving devices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increased Proportion of Lower Energy Density Items vs. Nutritional Labelling at an Online Supermarket
Status: COMPLETED
Conditions: Diet, Healthy|Food Selection
Interventions: BEHAVIORAL: Increased proportion of lower energy density items|BEHAVIORAL: Labelling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Role of Sodium Bicarbonate as Adjuvant Treatment of Computed Tomography Identified COVID-19 Pneumonia
Status: UNKNOWN
Conditions: Pneumonia|Covid19
Interventions: DRUG: Sodium Bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Educational Videos on Maternal Stress Whose Children Received Congenital Heart Disease Surgery: During COVID-19 Panic
Status: COMPLETED
Conditions: COVID-19|Educational Videos|Maternal|Uncertainty|Anxiety|Depression|Congenital Heart Disease|Children
Interventions: OTHER: Preoperative educational videos plus routine education|OTHER: Preoperative routine education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: HPV Vaccination Health-promotion Programme on Vaccine Acceptance and Uptake Among Female Adolescents
Status: COMPLETED
Conditions: HPV Infection|Health Behavior|Health Attitude
Interventions: OTHER: MDL-SHPVP|OTHER: 30-minute educational video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: CEGIR 7808: Use of Unsedated Transnasal Esophagoscopy (TNE) to Monitor Dietary Management of Eosinophilic Esophagitis in Children
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: OTHER: Transnasal esophagoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidemiology of Occult Hepatitis C Virus Infection in Patients Born Before 1969 in the Hospital Setting: a Spontaneous Opportunistic Screening Initiative.
Status: NOT_YET_RECRUITING
Conditions: Hepatitis C, Chronic|Hepatitis C|Hepatitis
Interventions: DIAGNOSTIC_TEST: Meridan Bioscience Point of Care test against HCV antibodies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Theranova Randomized, Controlled, Trial (RCT) in China
Status: RECRUITING
Conditions: Chronic Kidney Failure|Acute Kidney Failure
Interventions: DEVICE: Theranova 400 Dialyzer|DEVICE: FX 800 Dialyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization of Total Knee Arthroplasty Using Robotic Systems
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Total knee arthroplasty using the active robotic surgical system|DEVICE: TSolution One TCAT, and system for planning TPlan|PROCEDURE: total knee arthroplasty using the standard manual technic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Give Treatment Inside the Eye to Treat Retinoblastoma
Status: RECRUITING
Conditions: Bilateral Retinoblastoma|Childhood Intraocular Retinoblastoma|Group D Retinoblastoma|Stage I Retinoblastoma|Unilateral Retinoblastoma
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Carboplatin|DRUG: Etoposide|PROCEDURE: Examination Under Anesthesia|PROCEDURE: Magnetic Resonance Imaging|DRUG: Melphalan|PROCEDURE: Ultrasound Biomicroscopy|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Evaluation of Probiotics Product in Patients With Various Functional Bowel Disorders and Helicobacter Pylori Infection
Status: UNKNOWN
Conditions: Bowel Dysfunction|Helicobacter Pylori Infection
Interventions: DIETARY_SUPPLEMENT: Probiotics product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy, Immunogenicity and Safety of Inactivated ERUCOV-VAC Compared With Placebo in COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: ERUCOV-VAC 3 µg/0.5 ml Vaccine|BIOLOGICAL: ERUCOV-VAC 6 µg/0.5 ml Vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: CBD for Pain Following Orthopedic Shoulder Surgery
Status: RECRUITING
Conditions: Shoulder Osteoarthritis|Rotator Cuff Injuries
Interventions: DRUG: Epidiolex|DRUG: Placebo oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Back Rubs or Foot Flicks for Neonatal Stimulation at Birth in a Low-resource Setting
Status: UNKNOWN
Conditions: Neonatal Resuscitation
Interventions: PROCEDURE: Back rub stimulation|PROCEDURE: Foot flicks stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Auditory Stimulation During Verticalization With Erigo in Patients With Disorder of Consciousness
Status: UNKNOWN
Conditions: Consciousness Disorders
Interventions: OTHER: Erigo + Music|OTHER: Erigo + Metronome|OTHER: Erigo + Silence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long-Term Efficacy and Safety of Asenapine Using Olanzapine as a Positive Control (41512)(COMPLETED)(P05784)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Olanzapine|DRUG: Asenapine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Toremifene Citrate for the Reduction in the Risk of New Bone Fracture Occurrences in Men With Prostate Cancer
Status: WITHDRAWN
Conditions: Risk of Bone Fracture Occurrences
Interventions: DRUG: Toremifene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: ARTIFICIAL INTELLIGENCE FOR MASS SCREENING OF THE DIABETIC RETINOPATHY IN THE CHERNIVTSI REGION (Pilot Study)
Status: RECRUITING
Conditions: Diabetic Retinopathy
Interventions: DEVICE: taking fundus photos using non-mydriatic fundus camera - FundusScope Rodenstock
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1b Study to Assess the Safety and Anti-inflammatory Effects of Two Different Doses of SRT2104 in Patients With Ulcerative Colitis
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: DRUG: SRT2104
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Touch Methods in Preterm Infants During Endotracheal Aspiration
Status: COMPLETED
Conditions: Endotracheal Aspiration
Interventions: OTHER: Yakson touch|OTHER: Gentle Human Touch|OTHER: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wellness App for Sleep Disturbance in Hematological Cancer Patients
Status: RECRUITING
Conditions: Cancer|Sleep Disturbance|Anxiety|Depression|Inflammation|Fatigue
Interventions: BEHAVIORAL: Wellness app intervention #1|BEHAVIORAL: Wellness app intervention #2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Prospective Trial of Addition of Rituximab to Reduced Dose CHOP Chemotherapy in DLBC L Patients Aged 65 Years and Over
Status: UNKNOWN
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo-controlled Study of NPB-06 in Patients With Portal Vein Thrombosis
Status: COMPLETED
Conditions: Portal Vein Thrombosis
Interventions: DRUG: NPB-06|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Femoral Nerve Block on Opioid Requirements After Surgery for a Femur Fracture in Children
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Administration of a femoral nerve block (bupivacaine HCL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety & Effects of Autologous ADSCs During Recovery Phase of ST-Elevation MI Effects of Autologous ADSC Implantation During Subacute Recovery Phase of ST-Elevation Myocardial Infarction
Status: WITHDRAWN
Conditions: Subacute Myocardial Infarction
Interventions: PROCEDURE: Liposuction and stem cell implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Allogeneic Bone Marrow Transplantation Following Cyclophosphamide and Radiotherapy in Patients With Fanconi's Anemia
Status: COMPLETED
Conditions: Fanconi's Anemia
Interventions: DRUG: cyclophosphamide|PROCEDURE: Allogeneic Bone Marrow Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation With Expansion Study of EMB-01 in Participants With Advanced/Metastatic Solid Tumors
Status: RECRUITING
Conditions: Neoplasms|Neoplasm Metastasis|Non-Small-Cell Lung Cancer
Interventions: DRUG: EMB-01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Plus Cisplatin With or Without Bintrafusp Alfa (M7824) in Participants With 1L BTC
Status: TERMINATED
Conditions: Biliary Tract Cancer|Cholangiocarcinoma|Gallbladder Cancer
Interventions: DRUG: M7824|DRUG: Placebo|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IntelligentCare: Wearable-based Intervention
Status: RECRUITING
Conditions: Multimorbidity|Exercise|Sleep
Interventions: DEVICE: Activity watch monitoring|DEVICE: Sleep mattress monitoring|BEHAVIORAL: Physical activity counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LLIN Evaluation in Uganda Project (LLINEUP3)
Status: RECRUITING
Conditions: Malaria
Interventions: OTHER: long lasting insecticidal nets with chlorfenapyr-pyrethroid (PermaNet Dual)|OTHER: long lasting insecticidal nets with PBO-pyrethroid (PermaNet)|BEHAVIORAL: Social Behavior Change Communication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Pretreatment With Ibuprofen in Post-Electroconvulsive Therapy (ECT) Headache
Status: WITHDRAWN
Conditions: Mental Disorders
Interventions: DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Venous Thrombosis After Permanent Transvenous Leads Implantation
Status: COMPLETED
Conditions: Cardiac Pacing|Complications|Venous Thrombosis
Interventions: DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Waitlist-Control Trial of Smartphone CBT for Obsessive-Compulsive Disorder (OCD)
Status: WITHDRAWN
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Smartphone-delivered CBT for OCD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile App for Obsessive-compulsive Disorder in Adolescents
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder in Adolescence
Interventions: DEVICE: GGOC-AD (GG Obsessive-Compulsive Disorder - Adolescents)|DEVICE: GGN-AD (GG Neutral - Adolescents)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study of Ipragliflozin in Patients With Type 2 Diabetes Mellitus Receiving Insulin Therapy
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Ipragliflozin|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety And Efficacy Study Of ALG-1001 In Human Subjects With Wet Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: ALG 1001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visual and Auditory Breathing-swallowing Coordinated Training
Status: COMPLETED
Conditions: Breathing-Swallowing Coordination|Dysphagia Rehabilitation
Interventions: DEVICE: Visual and Auditory Breathing-swallowing Coordinated Training device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Task Shifting to Treat Depression and HIV Medication Nonadherence in Low Resource Settings
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections|Depression
Interventions: BEHAVIORAL: Stepped care for nonadherence and depression|OTHER: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Datopotamab Deruxtecan (Dato-DXd) in Combination With Pembrolizumab With or Without Platinum Chemotherapy in Subjects With Advanced or Metastatic Non-Small Cell Lung Cancer (TROPION-Lung02)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced or Metastatic NSCLC
Interventions: DRUG: Datopotamab deruxtecan|DRUG: KEYTRUDA®|DRUG: Carboplatin|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closure of Muscular Ventricular Septal Defects With The AMPLATZER™ Muscular VSD Occluder
Status: COMPLETED
Conditions: Heart Septal Defects, Ventricular
Interventions: DEVICE: Device closure with the AMPLATZER Muscular VSD Occluder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reversing the Effects of 0.5% Bupivacaine
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: DRUG: OraVerse|DRUG: Saline Water (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Effect of TRC101 on Progression of Chronic Kidney Disease in Subjects With Metabolic Acidosis
Status: TERMINATED
Conditions: Metabolic Acidosis|Chronic Kidney Disease
Interventions: DRUG: TRC101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation of Children and Parental Anxiety and Effectiveness of Breathing Exercises on Anxiety Reduction
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Anxiety
Interventions: BEHAVIORAL: Diaphragmatic Breathing|BEHAVIORAL: Bubble Blower Breathing|BEHAVIORAL: Tell Show Do
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Laparoscopic Antireflux Surgery Versus Endoscopic Full-thickness Gastroplication for Gastroesophageal Reflux Disease (GERD)
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: PROCEDURE: anti-reflux surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Study Evaluating Desvenlafaxine Succinate Sustained Release In Outpatients With Major Depressive Disorder
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: desvenlafaxine succinate sustained release|GENETIC: Genotyping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC-EBOMAB092-00-AB (MAb114), Administered Intravenously to Healthy Adults
Status: COMPLETED
Conditions: Healthy Adult Immune Responses to Vaccine
Interventions: BIOLOGICAL: VRC-EBOMAB092-00-AB (MAb114)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous CAngrelor in High-bleeding Risk Patients Undergoing percutaneouS Coronary Intervention (ICARUS) Registry
Status: UNKNOWN
Conditions: Bleeding|Coronary Artery Disease|Myocardial Infarction
Interventions: DRUG: Cangrelor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pramipexole to Target "Anhedonic Depression"
Status: COMPLETED
Conditions: Depression, Bipolar|Depression, Unipolar|Dysthymia|Anhedonia
Interventions: DRUG: Pramipexole Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Albuterol and Oxandrolone in Patients With Facioscapulohumeral Dystrophy (FSHD)
Status: COMPLETED
Conditions: Muscular Dystrophies
Interventions: DRUG: Albuterol|DRUG: Oxandrolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Significance of Platelet Reactivity on Clopidogrel During Off-pump Coronary Artery Bypass
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Dual antiplatelet therapy including aspirin and clopidogrel after off-pump coronary bypass surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Gene Transfer Therapy Study to Evaluate the Safety of SRP-9004 (Patidistrogene Bexoparvovec) in Participants With Limb-Girdle Muscular Dystrophy, Type 2D (LGMD2D)
Status: COMPLETED
Conditions: Limb-Girdle Muscular Dystrophy, Type 2D
Interventions: GENETIC: SRP-9004
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Operative Radiation Management of Adenocarcinoma of the Lower Rectum
Status: COMPLETED
Conditions: Cancer of Rectum|Cancer of the Rectum|Neoplasm, Rectum|Rectal Cancer|Rectum Cancer|Rectum Neoplasms|Adenocarcinoma of the Rectum
Interventions: RADIATION: Radiation|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Clinical Trial of a New Neuromodulation Device for Acute Attacks of Migraine in Children and Adolescents
Status: ACTIVE_NOT_RECRUITING
Conditions: Migraine Disorders
Interventions: DRUG: Ketorolac|DRUG: Metoclopramide|DEVICE: Active Remote Electrical Neuromodulation Device|DRUG: Placebo|DEVICE: Sham Remote Electrical Neuromodulation Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development of a Non-invasive Assessment of Human Bone Quality Using Spatially Offset Raman Spectroscopy
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis|Osteoporosis|Osteogenesis Imperfecta|Rickets / Osteomalacia|Bone Infection
Interventions: DEVICE: spatially offset Raman spectrometer (SORS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Vitamin D and Calcium Supplementation on Health and Well-being of Vitamin D Deficient UAE Citizens
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D and calcium|DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Calcium|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MK-8109 (Vintafolide) Given Alone or With Chemotherapy in Participants With Advanced Cancers (MK-8109-001)
Status: TERMINATED
Conditions: Advanced Cancer
Interventions: DRUG: Vintafolide|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dapagliflozin Treatment on Urinary Proteomic Patterns in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Diabetic Nephropathy
Interventions: DRUG: Dapagliflozine 10 mg once daily tablet treatment|DRUG: Placebo identical once daily tablet treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Pilsicainide After Radiofrequency Ablation of Paroxysmal Atrial Fibrillation
Status: UNKNOWN
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DRUG: pilsicainide|DRUG: other class IC antiarrhythmic drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capillary Glycerolemia Evolution During Physical Exercise
Status: COMPLETED
Conditions: Physical Activity|Body Mass Index
Interventions: OTHER: Physical exercice - moderate intensity|OTHER: Physical exercice - high intensity|OTHER: Physical exercice - workout|OTHER: Normal meal|OTHER: Normalized meal|OTHER: Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of MK-4830 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-4830-001)
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoplasms
Interventions: DRUG: MK-4830|DRUG: Pembrolizumab|DRUG: Carboplatin|DRUG: Pemetrexed|DRUG: Lenvatinib|DRUG: Paclitaxel|DRUG: Cisplatin|BIOLOGICAL: MK-4830A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feraheme As An MRI Contrast Agent For Pediatric Congenital Heart Disease
Status: COMPLETED
Conditions: Pediatric Congenital Heart Disease
Interventions: DRUG: ferumoxytol|DRUG: gadofosveset
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of a Strategy Based on Bacterial DNA Detection to Optimize Antibiotics in Immunocompromised Patients With Hospital-acquired Pneumonia Requiring Mechanical Ventilation
Status: RECRUITING
Conditions: Pneumonia, Ventilator-Associated|Pneumonia, Hospital-Acquired|Immunodeficiency
Interventions: OTHER: PCR based strategy|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Atypical Antipsychotic Drugs Olanzapine and Amisulpride on Glucose Metabolism
Status: COMPLETED
Conditions: Schizophrenia|Diabetes|Insulin Resistance
Interventions: PROCEDURE: Glucose clamp technique|DRUG: Amisulpride|DRUG: Olanzapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety of Single Doses of Peginesatide in Patients With Chronic Kidney Disease
Status: TERMINATED
Conditions: Anemia|Chronic Kidney Disease|Chronic Renal Failure
Interventions: DRUG: Placebo|DRUG: peginesatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SCMC Trial on KHE With KMP (V.2020)
Status: UNKNOWN
Conditions: Kaposiform Hemangioendothelioma (KHE) With Kasabach-Merritt Phenomenon (KMP)
Interventions: DRUG: prednison and Sirolimus|DRUG: prednison
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Adductor Canal Block vs. Placebo on Muscle Strength, Mobilisation and Pain After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Replacement Arthroplasty
Interventions: DRUG: Ropivacaine 7,5 mg/ml|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect od Beetroot Juice on Forearm Muscle Strength and Muscle EMG Activity After BloodFlow Restriction
Status: RECRUITING
Conditions: Muscle Strength
Interventions: DIETARY_SUPPLEMENT: Beetroot juice|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of a Probiotic on Upper Respiratory Tract Infections
Status: COMPLETED
Conditions: Infections, Upper Respiratory Tract
Interventions: DIETARY_SUPPLEMENT: Probiotic strain|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Spinal Stabilization Exercises on Dynamic Balance and Functional Performance in Adults With Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain|Chronic Low Back Pain|Subacute Low Back Pain
Interventions: OTHER: Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Preoperative Anxiety Score to Determine the Total Dose of Butorphanol for Sedation
Status: COMPLETED
Conditions: Preoperative Anxiety Score|Total Dose of Butorphanol
Interventions: DRUG: Butorphanol|OTHER: physiological saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nasogastric/Oral Gastric Tube Placement in Infants: Comparing 2 Measurement Methods
Status: TERMINATED
Conditions: Enteral Tube Placement
Interventions: OTHER: enteral tube placement accuracy|OTHER: NEM method for NG/OG tube placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Nutrition and Lifestyle Changes in Patients With Previously Untreated Stage I or Stage II Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: exercise intervention|GENETIC: gene expression analysis|GENETIC: polymerase chain reaction|GENETIC: proteomic profiling|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: laboratory biomarker analysis|OTHER: medical chart review|OTHER: questionnaire administration|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment|PROCEDURE: support group therapy|PROCEDURE: therapeutic dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Cryoballoon Pulmonary Vein Isolation for Atrial Fibrillation With Heart Failure
Status: RECRUITING
Conditions: Atrial Fibrillation|Heart Failure|Cryoballon Ablation
Interventions: PROCEDURE: Cryoballoon Pulmonary Vein Isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GIP/GLP-1 Co-Activity in Subjects With Obesity: Lowering of Food Intake
Status: COMPLETED
Conditions: Obesity|Adiposity|Type 2 Diabetes
Interventions: OTHER: IIGI+GIP|OTHER: IIGI+GLP-1|OTHER: IIGI+NaCl (placebo)|OTHER: OGTT|OTHER: IIGI+GIP+GLP-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Plantar Pressure Analysis and Foot Biomechanics in Lipedema and Chronic Venous Disease
Status: COMPLETED
Conditions: Chronic Venous Insufficiency|Lipedema
Interventions: OTHER: Presence of foot deformity, ankle range of motion, foot posture, local tissue water percentage, and foot pressure distribution will be evaluated in patients with chronic venous disease.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study for Beinaglutide Versus Glargine Therapy in Glycemic Variability of Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Beinaglutide|DRUG: glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TREAD: Time Restricted Eating Intervention for Alzheimer's Disease
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment|Alzheimer Disease
Interventions: BEHAVIORAL: Time-restricted eating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prison Connect-STI/HIV Prevention Intervention for Couples Affected by Incarceration
Status: COMPLETED
Conditions: Incarceration
Interventions: BEHAVIORAL: Speaker/Listener technique|BEHAVIORAL: Social Support|BEHAVIORAL: Problem-Solving|BEHAVIORAL: Goal Setting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multicentre Trial to Evaluate the Safety and Efficacy of CP-316,311 in Major Depressive Disorder
Status: TERMINATED
Conditions: Depressive Disorder, Major
Interventions: DRUG: CP-316,311|DRUG: Placebo|DRUG: Sertraline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Infliximab (Remicade ) to Treat Dermatomyositis and Polymyositis
Status: COMPLETED
Conditions: Dermatomyositis|Polymyositis
Interventions: DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proton Beam Therapy in the Treatment of Esophageal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophagus Cancer|Esophageal Cancer|Cancer of the Esophagus
Interventions: RADIATION: Proton beam therapy|OTHER: Patient-Reported Outcome Measures
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Vorinostat and Sorafenib in Advanced Cancer
Status: COMPLETED
Conditions: Malignant Solid Tumour|Renal Cell Carcinoma|Non Small Cell Lung Carcinoma
Interventions: DRUG: Sorafenib|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liposomal Bupivacaine in Bariatric Surgery
Status: COMPLETED
Conditions: Bariatric Surgery Analgesia
Interventions: DRUG: Liposomal Bupivacaine TAP block|DRUG: Bupivacaine TAP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Induction Chemotherapy Followed by Chemoradiation With Cetuximab in Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: docetaxel, cisplatin, 5-fluorouracil|RADIATION: radiotherapy|DRUG: cetuximab, cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Center for Stroke Disparities Solution - Community Transitions Intervention
Status: COMPLETED
Conditions: Hypertension|Stroke|Transient Ischemic Attack
Interventions: BEHAVIORAL: Nurse Practitioner Only|BEHAVIORAL: Nurse Practitioner + Health Coach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Roflumilast and TMS Motor Plasticity
Status: NOT_YET_RECRUITING
Conditions: Other Conditions of Brain
Interventions: DRUG: Roflumilast|DRUG: Placebo|DEVICE: Intermittent theta-burst stimulation transcranial magnetic stimulation|DEVICE: Continuous theta-burst stimulation transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Comparing the Amount of Metformin and After Taking a Combination Tablet vs. Separate Tablets
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Dapagliflozin/Metformin|DRUG: Dapagliflozin|DRUG: Metformin|DRUG: Dapagliflozin/Metformin|DRUG: Dapagliflozin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Green Tea and Tai Chi for Bone Health
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Placebo|DRUG: Green Tea Polyphenols (GTP)|DRUG: Placebo+Tai Chi (TC)|DRUG: GTP+TC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Prasugrel (CS-747) and Clopidogrel in Acute Coronary Syndrome Subjects Who Are to Undergo Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Coronary Arteriosclerosis|Acute Coronary Syndromes
Interventions: DRUG: Prasugrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New Technologies to Help Manage ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: OTHER: enhanced myADHDportal.com|OTHER: treatment as usual standard portal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Perfusion Evaluation by Real-time Fluorescence-based Enhanced Reality of Anastomosis
Status: COMPLETED
Conditions: Sigmoid Diverticulosis|Sigmoid Diverticulitis|Colorectal Malignancy
Interventions: PROCEDURE: Left-sided colonic resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Oxcarbazepine in the Treatment of Agitation / Aggression in Dementia (OBAD)
Status: COMPLETED
Conditions: Agitation Aggression in Dementia
Interventions: DRUG: Oxcarbazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Intra-articular Injection of Allogeneic Platelet Rich Plasma (PRP) for Adhesive Capsulitis
Status: COMPLETED
Conditions: Adhesive Capsulitis
Interventions: PROCEDURE: Steroid injection into the glenohumeral joint|PROCEDURE: Allogeneic PRP injection into the glenohumeral joint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety of Multi-Dose MEDI-545 in Adult Patients With Dermatomyositis or Polymyositis
Status: COMPLETED
Conditions: DERMATOMYOSITIS OR POLYMYOSITIS
Interventions: BIOLOGICAL: MEDI-545|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Helium Oxygen Mixture in the Treatment of Meconium Aspiration Syndrome
Status: COMPLETED
Conditions: Neonatal Meconium Aspiration
Interventions: DEVICE: helium oxygen mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan, Cisplatin, and Radiation Therapy With or Without Celecoxib in Treating Patients With Stage II, Stage III, or Stage IV Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: CPT- 11|DRUG: Cisplatin|DRUG: Celecoxib|RADIATION: Radiation|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT