pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect Of Biomechanical Stimulation On Skeletal Health In Adolescent And Young Women With Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa
Interventions: DEVICE: Low-magnitude mechanical stimulation platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate
Status: RECRUITING
Conditions: Chronic Hepatitis B
Interventions: BIOLOGICAL: HEPLISAV B; TherVacB|BIOLOGICAL: TherVacB
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ABI-2280 Vaginal Tablet in Participants With Cervical Intraepithelial Neoplasia
Status: RECRUITING
Conditions: Cervical Intraepithelial Neoplasia
Interventions: DRUG: ABI-2280
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Micronutrients in Management of Symptomatic Oral Lichen Planus
Status: COMPLETED
Conditions: Oral Lichen Planus
Interventions: DIETARY_SUPPLEMENT: Zinc sulphate heptahydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation Pharmacotherapy-Nurse Practitioner Led Tobacco Treatment Team Study
Status: RECRUITING
Conditions: Cardiopulmonary Disease|Smoking Cessation|Inpatient
Interventions: OTHER: Enhanced Usual Care (EUC)|OTHER: Nurse Practitioner Tobacco Treatment Team (NPT3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of 1146A Nasal Spray in Adult Participants With Symptoms of Common Cold
Status: COMPLETED
Conditions: Common Cold
Interventions: DRUG: Carbomer 980 (1146A)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ARQ 197 for Participants With Relapsed or Refractory Germ Cell Tumors
Status: TERMINATED
Conditions: Non-CNS Germ Cell Tumors (Seminomas and Nonseminomas)
Interventions: DRUG: Tivantinib (ARQ 197)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Balanced Knee System Clinical Protocol for IRB Approval
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Rheumatoid Arthritis of Knee|Post-traumatic Osteoarthritis of Knee Nos|Valgus Deformity
Interventions: DEVICE: Balanced Knee System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Causal Relation of Nasal Nitric Oxide Levels to the Severity of Chronic Rhinosinusitis and Its Inflammatory Phenotype
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Rhinosinusitis (Diagnosis)
Interventions: DRUG: Fluticasone Propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Biomonitoring of Internal Exposure to MNPLs, and Its Effects, in Blood of Patients With Chronic Kidney Disease (CKD)
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Microplastics|Nanoplastics|Genotoxic Damage
Interventions: OTHER: Biomonitoring study to detect MNPLs in biological samples and study of their health effects
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Behavioural Problems in Huntington Disease : Analysis and Enhancement of Caregiver and Patient Experience
Status: TERMINATED
Conditions: Huntington Disease
Interventions: BEHAVIORAL: questionnaire qualilty of life|BEHAVIORAL: psychological interview|BEHAVIORAL: psychological tests|OTHER: Motor evaluation|BEHAVIORAL: Behavioral evaluation|BEHAVIORAL: cognitive tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Greenlight Plus Study: Approaches to Early Childhood Obesity Prevention
Status: COMPLETED
Conditions: Behavior, Health|Child Obesity
Interventions: BEHAVIORAL: Greenlight Plus|BEHAVIORAL: Greenlight
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Carboxypeptidase-G2 in Treating Nervous System Toxic Effects in Patients Given an Overdose of Intrathecal Methotrexate
Status: COMPLETED
Conditions: Neurotoxicity|Unspecified Adult Solid Tumor, Protocol Specific|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: glucarpidase
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Retrospective/Prospective Data Collection on the LDR ROIC Interbody Fusion Device With VerteBRIDGE Plating
Status: COMPLETED
Conditions: Degenerative Disc Disease
Interventions: DEVICE: ROIC interbody cage with VerteBRIDGE plating
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SMS-based Summons in Cervical Screening
Status: RECRUITING
Conditions: Cervical Cancer|Uterine Cervical Neoplasm|Uterine Neoplasms|Genital Neoplasm|Genital Neoplasm, Female|Uterine Diseases|Genital Diseases, Female|Neoplasms by Site|Neoplasms|Uterine Cervical Disease
Interventions: OTHER: Sending of screening summon.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cost-utility and Immuno-inflammatory Effects of the FIBROWALK in Patients With Fibromyalgia (the On&Out Study)
Status: UNKNOWN
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: TAU + FIBRO-On|BEHAVIORAL: TAU + FIBRO-Out|OTHER: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Preconditioning on Intramuscular High-Energy Phosphate Levels During Ischemia
Status: UNKNOWN
Conditions: Ischemia
Interventions: PROCEDURE: preconditioning|PROCEDURE: no preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Safety and Efficacy of HPN-100 in Subjects With Cirrhosis and Episodic Hepatic Encephalopathy
Status: COMPLETED
Conditions: Cirrhosis|Hepatic Encephalopathy
Interventions: DRUG: HPN-100|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nitroglycerin Plus Intracranial Radiotherapy for Brain Metastases in NSCLC Patients
Status: COMPLETED
Conditions: Phase II Clinical Trial|Ninety-six Histologically Confirmed NSCLC Patients With BM|Randomized 1:1 to Received TN Plus WBR or Only WBR|ICPFS Evaluated by Two Blinded and Independent Radio-oncologist With MRI
Interventions: RADIATION: Whole-brain radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SurgiMend in Two-stage Implant-based Breast Reconstruction in Patients With Pre-Mastectomy Radiotherapy
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DEVICE: SurgiMend® PRS|OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing the Interchangeability Between TRS003 and Bevacizumab® For CRC
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer (CRC)
Interventions: BIOLOGICAL: TRS003|BIOLOGICAL: China-approved Bevacizumab|DRUG: mFOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib With Rituximab and Lenalidomide for Patients With Recurrent/Refractory Primary or Secondary Central Nervous System Lymphoma (PCNSL/SCNSL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Central Nervous System Lymphoma (PCNSL)|Secondary Central Nervous System Lymphoma (SCNSL)
Interventions: DRUG: Ibrutinib|DRUG: Lenalidomide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Misoprostol for Small Bowel Ulcers and Obscure Bleeding Due to Aspirin or Nonsteroidal Antiinflammatory Drugs
Status: COMPLETED
Conditions: Chronic Arthritis|Ischemic Heart Disease|Atrial Fibrillation|Anemia|Bleeding
Interventions: DRUG: Misoprostol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Regorafenib Maintenance Therapy in Patients With Metastatic Colorectal Cancer (mCRC)
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes And Hypertension (MK-8835-042)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Hypertension
Interventions: DRUG: Placebo to Ertuglilflozin 1 or 5 mg|DRUG: Ertugliflozin 1 mg|DRUG: Ertugliflozin 5 mg|DRUG: Ertugliflozin 25 mg|DRUG: HCTZ 12.5mg|DRUG: Placebo to HCTZ|DRUG: Placebo to ertuglilflozin 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy Study of the Evidence-Based Psychological Intervention for Improving Resilience and Preventing Burnout of Residents
Status: UNKNOWN
Conditions: Burn Out (Psychology)
Interventions: BEHAVIORAL: TSC program (Three Self-Commitment program)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Girl Empower: Studying the Impact of Mentorship, Asset Building, Caregiver Discussion Groups, and Cash Transfers on Reducing Girl's Vulnerability to Sexual Exploitation and Abuse
Status: UNKNOWN
Conditions: Adolescent Behavior|Sexual Violence
Interventions: BEHAVIORAL: Girl Empower Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Relationship Between Serum Endocan and ADMA Levels and Penile Doppler Ultrasonography in Erectile Dysfunction
Status: COMPLETED
Conditions: Evaluation of the Relationship Between Serum Biomarkers (Endocan and ADMA) and Penile Doppler Ultrasonography Findings of Patients With Severe Erectile Dysf
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate
Status: COMPLETED
Conditions: Blood Loss, Surgical|Blood Loss, Postoperative
Interventions: DRUG: Oxytocin ,Tranexamic acid and Ethamsylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Zalypsis® (PM00104) in Patients With Unresectable Locally Advanced and/or Metastatic Ewing Family of Tumors (EFT) Progressing After at Least One Prior Line of Chemotherapy
Status: COMPLETED
Conditions: Ewing's Sarcoma|Primitive Neuroectodermal Tumor (PNET)|Askin's Tumor of the Chest Wall|Extraosseous Ewing's Sarcoma (EOE)
Interventions: DRUG: Zalypsis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tirelizumab in Combination With Chemoradiation in Patients With Unresectable Gastric Cancer or Gastroesophageal Junction Adenocarcinoma
Status: RECRUITING
Conditions: Locally Advanced Gastric Cancer
Interventions: DRUG: Nab-PTX,S-1,Tirelizumab|RADIATION: Chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fibrin Glue Versus Titanium Platelet-rich Fibrin in Lateral Sinus Lifting
Status: COMPLETED
Conditions: Sinus Floor Augmentation|Graftless Sinus Elevation
Interventions: OTHER: Fibrin Glue|OTHER: T-PRF|OTHER: Negative control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RELY-ABLE Long Term Multi-center Extension of Dabigatran Treatment in Patients With Atrial Fibrillation Who Completed RE-LY Trial
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: dabigatran dose 1|DRUG: dabigatran dose 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Dose Study of CTI-1601 Versus Placebo in Subjects With Friedreich's Ataxia
Status: COMPLETED
Conditions: Friedreich Ataxia
Interventions: BIOLOGICAL: CTI-1601|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of the Histone-Deacetylase Inhibitor ITF2357 Followed by Mechlorethamine in Relapsed/Refractory Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Hodgkin's Lymphoma
Interventions: DRUG: ITF2357
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does The Combined Use Of Local And Intravenous Tranexamic Acid Offer Better Surgical Field Quality During Functional Endoscopic Sinus Surgery? A Placebo-Controlled Clinical Trial
Status: UNKNOWN
Conditions: Chronic Sinus Disease|Nasal Polyps
Interventions: DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of PDR001 in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Spartalizumab|DRUG: Investigator choice of chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain After Laparoscopy Results From the Incision, Manipulation of the Abdominal Organs, and Retained CO2(Back Pain)
Status: UNKNOWN
Conditions: Post Operative Pain, Acute
Interventions: DRUG: intraperitoneal Magnesium sulfate|DRUG: intravenous magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Biological Evaluation of Dietary Supplement Liposomal Glutathione
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DIETARY_SUPPLEMENT: Liposomal glutathione|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: System Accuracy of a Blood Glucose Monitoring System GlucoSpark/GlucoScore
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DIAGNOSTIC_TEST: Glucometer Test|DIAGNOSTIC_TEST: blood glucose measurement, laboratory reference device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Adjuvant Docetaxel and Trastuzumab in Stage I HER2-positive Breast Cancer
Status: RECRUITING
Conditions: HER2-positive Breast Cancer|Adjuvant Therapy
Interventions: DRUG: Paclitaxel|DRUG: Trastuzumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A RCT of UBE vs. MIS-TLIF in Lumbar Spondylolisthesis
Status: NOT_YET_RECRUITING
Conditions: Lumbar Spondylolisthesis|Unilateral Biportal Endoscopy|Minimally Invasive Technique|Surgical Treatment
Interventions: PROCEDURE: surgical treatment for lumbar spondylolisthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Chondron (Autologus Chondrocyte) in Patients With Cartilage Defects in Their Ankle
Status: UNKNOWN
Conditions: Defect of Articular Cartilage|Degenerative Joint Disease of Ankle and/or Foot|Ankle (Ligaments); Instability, Familial
Interventions: DRUG: CHONDRON
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dextenza for Corneal Crosslinking
Status: ENROLLING_BY_INVITATION
Conditions: Keratoconus
Interventions: DRUG: Dextenza 0.4Mg Ophthalmic Insert|DRUG: topical prednisolone acetate 1% (PredForte) eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Block Versus Rectus Sheath Block After Cesarean Delivery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Transversus abdominis plane block|PROCEDURE: Rectus sheath block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Danirixin Dose Ranging Study in Participants With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Danirixin|DRUG: Danirixin matching placebo|DRUG: Standard of care|DRUG: Rescue medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prasugrel Versus Double Dose Clopidogrel to Treat Clopidogrel Low-responsiveness After PCI
Status: COMPLETED
Conditions: Coronary Artery Disease|Percutaneous Coronary Intervention|Acute Coronary Syndromes
Interventions: DRUG: clopidogrel|DRUG: Prasugrel 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of TAK-733 in Adult Patients With Advanced Nonhematologic Malignancies
Status: COMPLETED
Conditions: Advanced Non-hematologic Malignancies|Advanced Metastatic Melanoma
Interventions: DRUG: TAK-733
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clear Vision Study
Status: COMPLETED
Conditions: Posterior Vitreous Detachment|Vitreous Floaters
Interventions: PROCEDURE: Laser Ablation of Floaters|PROCEDURE: Sham Laser Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Noradrenaline Versus Glypressin for Prevention of Hypotension After Deflation of Tourniquet in Knee Arthroplasty
Status: COMPLETED
Conditions: Norepinephrine, Glypressin, Tourniquet Deflation|Hypotension
Interventions: DRUG: Saline|DRUG: Norepinephrine|DRUG: glypressin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Drug Interaction Study Following Co-administration of Valsartan, Hydrochlorothiazide and Amlodipine in Patients With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Valsartan/hydrochlorothiazide (HCTZ)|DRUG: Valsartan/amlodipine|DRUG: Amlodipine/hydrochlorothiazide(HCTZ)|DRUG: Valsartan/amlodipine/hydrochlorothiazide(HCTZ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Intervention With High Phenolic EVOO in CLL
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia (CLL)
Interventions: DIETARY_SUPPLEMENT: High phenolic EVOO intake|DIETARY_SUPPLEMENT: No High phenolic EVOO intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Single and Multiple-dose Methotrexate Therapy for Ectopic Pregnancy
Status: COMPLETED
Conditions: Pregnancy, Ectopic
Interventions: DRUG: Single|DRUG: Multipe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Propofol Injection for Daily Headache
Status: COMPLETED
Conditions: Chronic Headache|Analgesic Rebound Headache|Chronic Daily Headache|Headache, Intractable
Interventions: DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of Cerclage Versus 17 α-Hydroxyprogesterone Caproate for Treatment of a Short Cervix
Status: TERMINATED
Conditions: Mid Trimester Cervical Shortening
Interventions: PROCEDURE: McDonald cerclage placement|DRUG: 17 hydroxyprogesterone caproate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Changes in Retrofoveolar Choroidal Thickness During Aerobic Exercise
Status: UNKNOWN
Conditions: Choroid Disease|Hypertension Ocular
Interventions: OTHER: Examination of pressures before stopping the exercise|OTHER: Examination of pressure during the exercise|OTHER: Examination of pressures after stopping the exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Telitacicept for the Treatment of Moderately to Severely Active Systemic Lupus Erythematosus (REMESLE-2)
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Telitacicept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Docosahexaenoic and Eicosapentaenoic Acids in Hypercholesterolemic Children Plus Diet on Docosahexaenoic Acid (DHA) Status
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Docosahexaenoic acid|DIETARY_SUPPLEMENT: Docosahexaenoic acid (DHA)+ Eicosapentaenoic acid (EPA)|DIETARY_SUPPLEMENT: Germ oil|OTHER: National Cholesterol Education Program (NCEP) Step I Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Dependent Effects of tDCS on Post-Operative Pain
Status: COMPLETED
Conditions: Total Knee Arthroplasty (Postoperative Pain)|Total Hip Arthroplasty(Postoperative Pain)
Interventions: DEVICE: 4 Real sessions of Transcranial Direct Current Stimulation|DEVICE: 2 Real Sessions of Transcranial Direct Current Stimulation|DEVICE: 1 Real Session of Transcranial Direct Current Stimulation|DEVICE: Sham Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 3D Titanium Miniplates Versus 3D Titanium Mesh Method of Fixation for Double Barrel Vascularized Fibular Graft
Status: COMPLETED
Conditions: Fixation of Double Barrel Vascularized Fibula
Interventions: OTHER: fixation of double barrel vascularised fibula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a 3-dose Vaccination Regimen With One of Three Ascending Dose Levels of Clostridium Difficile Vaccine With or Without Adjuvant in Healthy Adults Aged 50 to 85 Years
Status: COMPLETED
Conditions: Clostridium Difficile Associated Disease
Interventions: BIOLOGICAL: C. difficile vaccine|BIOLOGICAL: C. difficile vaccine +adjuvant|BIOLOGICAL: C. difficile vaccine|BIOLOGICAL: C. difficile vaccine +adjuvant|BIOLOGICAL: C. difficile vaccine|BIOLOGICAL: C. difficile vaccine +adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: High-resolution, Relational, Resonance-based, Electroencephalic Mirroring (HIRREM) to Relieve Insomnia
Status: COMPLETED
Conditions: Insomnia
Interventions: DEVICE: HIRREM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Blended Learning to Enhance Communication Skill Competence and Self-Efficacy of Nursing Students in Clinical Handovers
Status: COMPLETED
Conditions: Self Efficacy|Nursing|Communication
Interventions: OTHER: A Blended Learning Programme|OTHER: Waitlist control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial of HG146 Administered to Subjects With Advanced Solid Tumors or Lymphoma
Status: RECRUITING
Conditions: Solid Tumor|Lymphoma
Interventions: DRUG: HG146|DRUG: PD-(L)1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-escalating, Safety, Tolerability and PK Study of TAS-119 in Combination With Paclitaxel in Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumors
Interventions: DRUG: TAS-119|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: What is Optimal Post-operative Prophylactic Therapy in Irradiated Breasts Undergoing Repeat Surgery
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: TMP-SMX DS|DEVICE: ciNPT dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study to Evaluate the Safety, Pharmacokinetics and Efficacy of PRJ1-3024 in Subjects With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|Advanced Solid Malignancies
Interventions: DRUG: PRJ1-3024
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SAR231893-LPS15497- "Dupilumab Effect on Sleep in AD Patients"
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Dupilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-Finding Study of Folotyn® (Pralatrexate Injection) Plus CHOP With Peripheral T-Cell Lymphoma (PTCL)
Status: COMPLETED
Conditions: Peripheral T-Cell Lymphoma (PTCL)
Interventions: DRUG: Pralatrexate Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INFLUENCE OF COMBINED INTERFERENTIAL CURRENT STIMULATION AND ABDOMINAL DRAW-IN EXERCISES IN THE TREATMENT OF CHRONIC NON-SPECIFIC LOW BACK PAIN
Status: RECRUITING
Conditions: to Investigate Influence of a Combined Interferential Current Stimulation and Abdominal Draw -in Exercises in Patients With Chronic n
Interventions: DEVICE: Interferential current stimulation|OTHER: Draw- In exercises,,
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultralow Dose PAH Binary Mixture Study
Status: COMPLETED
Conditions: Environmental Exposure
Interventions: DRUG: [14C]-benzo[a]pyrene|DRUG: [14C]-benzo[a]pyrene plus phenanthrene
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: CT-guided Localization for Micro Hepatocellular Carcinoma Before Surgical Resection
Status: RECRUITING
Conditions: Cirrhosis, Liver|Hepatocellular Carcinoma
Interventions: PROCEDURE: CT-guided localization for micro hepatocellular carcinoma before surgical resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness Transdermal Compress Device in Participants With Transfemoral Amputations
Status: RECRUITING
Conditions: Prosthesis and Implants
Interventions: DEVICE: Transdermal Compress Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction Chemo w/ABVD Followed by Brentuximab Vedotin Consolidation in Newly Diagnosed, Non-Bulky Stage I/II Hodgkin Lymphoma
Status: COMPLETED
Conditions: Hodgkin Lymphoma, Adult
Interventions: DRUG: Brentuximab vedotin|DRUG: ABVD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VALERIA: Valsartan in Combination With Lisinopril in Hypertensive Patients With Microalbuminuria
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: valsartan|DRUG: lisinopril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Exercise-Induced Gut Permeability in Normal-weight Obesity
Status: RECRUITING
Conditions: Normal-weight Obesity|Obesity
Interventions: OTHER: Exercise tests (VO2 max test and 45-minute exercise session at 65% VO2 max)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: COronary Native Artery First in Man Investigation of ISA 247 Elution to Prevent Restenotic Mechanisms (CONFIRM 1)
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DEVICE: CINATRA™ Coronary Stent System|DEVICE: CINATRA™ ISA 247 Coated Coronary Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sourdough Bread Consumption on Postprandial Responses, Appetite Regulation and Energy Intake
Status: COMPLETED
Conditions: Appetite|Satiety|Energy Intake|Glucose Response|Insulin Response|Gastric Emptying
Interventions: DIETARY_SUPPLEMENT: Dietary Intervention with Wholemeal Bread with Yeast|DIETARY_SUPPLEMENT: Dietary Intervention with Wholemeal Sourdough Bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Double-blind Study to Investigate Efficacy, Safety and Tolerability of BAY 1142524 in Patients After Acute Myocardial Infarction With Left-ventricular Dysfunction
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Fulacimstat (BAY1142524)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Bone Marrow Failure Syndrome|Severe Aplastic Anemia|Severe Congenital Neutropenia|Amegakaryocytic Thrombocytopenia|Diamond-Blackfan Anemia|Schwachman Diamond Syndrome|Primary Immunodeficiency Syndromes|Acquired Immunodeficiency Syndromes|Histiocytic Syndrome|Familial Hemophagocytic Lymphocytosis|Lymphohistiocytosis|Macrophage Activation Syndrome|Langerhans Cell Histiocytosis (LCH)|Hemoglobinopathies|Sickle Cell Disease|Sickle Cell-beta-thalassemia
Interventions: BIOLOGICAL: CD34 Stem Cell Selection Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Ophthalmology Treatment Study
Status: UNKNOWN
Conditions: Retinal Disease|Macular Degeneration|Hereditary Retinal Dystrophy|Optic Nerve Disease|Glaucoma
Interventions: PROCEDURE: RB (Retrobulbar)|PROCEDURE: ST (Subtenon)|PROCEDURE: IV (Intravenous)|PROCEDURE: IVIT (Intravitreal)|PROCEDURE: IO (Intraocular)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Efficacy of Lenvatinib Versus Sorafenib in the Management of Advanced Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess Immune Response Following Primary Vaccination With Tritanrix™-HepB Vaccine Mixed With 3 Formulations of Hib-MenAC Vaccine to Infants
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Hepatitis B|Hib Diseases|Neisseria Meningitidis Serogroups A & C Diseases
Interventions: BIOLOGICAL: DTPw-HBV/Hib-MenAC conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tarceva With or Without Apatinib in the Advanced Lung Adenocarcinoma
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: Apatinib|DRUG: Tarceva|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiation Therapy and Bintrafusp Alfa for the Treatment of Advanced Intrahepatic Cholangiocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Intrahepatic Cholangiocarcinoma|Metastatic Intrahepatic Cholangiocarcinoma|Stage III Intrahepatic Cholangiocarcinoma AJCC v8|Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8|Stage IIIB Intrahepatic Cholangiocarcinoma AJCC v8|Stage IV Intrahepatic Cholangiocarcinoma AJCC v8
Interventions: DRUG: Bintrafusp Alfa|PROCEDURE: Biopsy|RADIATION: Hypofractionated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Recovery Workbook as a Psychoeducational Tool for Facilitating Recovery
Status: COMPLETED
Conditions: Mental Disorders
Interventions: BEHAVIORAL: Recovery Workbook Training (psychoeducational training)|BEHAVIORAL: ACT as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of DCC-3116 in Combination With Anticancer Therapies in Participants With Advanced Malignancies
Status: RECRUITING
Conditions: GIST
Interventions: DRUG: DCC-3116|DRUG: Ripretinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Abrocitinib Compared With Dupilumab in Adults With Moderate to Severe Atopic Dermatitis on Background Topical Therapy
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Abrocitinib 200 mg|COMBINATION_PRODUCT: Dupilumab 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells for The Treatment of Acute Respiratory Distress Syndrome (ARDS)
Status: NOT_YET_RECRUITING
Conditions: Acute Respiratory Distress Syndrome
Interventions: BIOLOGICAL: UMC119-06
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Epcoritamab With or Without Lenalidomide as First Line Therapy for Diffuse Large B-Cell Lymphoma
Status: RECRUITING
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: BIOLOGICAL: Epcoritamab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Icosapent Ethyl on Vascular Progenitor Cells in Individuals With Elevated Cardiovascular Risk
Status: COMPLETED
Conditions: Cardiovascular Diseases|Cardiovascular Risk Factor|Triglycerides High|Diabetes Mellitus, Type 2
Interventions: DRUG: Icosapent Ethyl 1000 MG Oral Capsule [Vascepa]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Evaluation of Self-Testing to Increase Screening
Status: ENROLLING_BY_INVITATION
Conditions: Cervical Cancer|Human Papillomavirus Infection
Interventions: BEHAVIORAL: Telephone Recall|BEHAVIORAL: Mailed HPV Self-Sampling Kit|BEHAVIORAL: Patient Navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Safety & Efficacy Study of EGF Cancer Vaccine to Treat Stage IV Biomarker Positive, Wild Type EGF-R NSCLC Patients
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: BIOLOGICAL: EGF Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Nerve Stimulation in Uncontrolled Hypertensive Patients Undergoing Renal Denervation
Status: RECRUITING
Conditions: Hypertension
Interventions: PROCEDURE: nerve stimulation guided renal denervation procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Objectives of This Study Are Comparative Assessment of the Tolerability, Safety and Immunogenicity of the Flu-M Vaccine vs. the Ultrix® Vaccine by Single Vaccination of Children Aged 6 to 17 Years.
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Flu-M [Inactivated split influenza vaccine]|BIOLOGICAL: Inactivated Split Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Computer Guided Versus Conventional Arthrocentesis in Management of Internal Derangements: A Randomized Clinical Study
Status: COMPLETED
Conditions: TMJ - Oral &Maxillofacial Surgery
Interventions: PROCEDURE: Computer Guided Arthrocentesis|PROCEDURE: Conventional Arthrocentesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ranibizumab for Edema of the mAcula in Diabetes: Protocol 4 With Tocilizumab: The READ-4 Study
Status: WITHDRAWN
Conditions: Diabetic Macular Edema
Interventions: DRUG: Tocilizumab|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Neck Isometric Exercises and Cervical Mobilization on Cervical Radiculopathy
Status: COMPLETED
Conditions: Cervical Radiculopathy
Interventions: OTHER: Isometric exercises|OTHER: Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Fermented Velvet Antler Extract on Fatigue Recovery After Exercise
Status: COMPLETED
Conditions: Chronic Fatigue Syndrome
Interventions: DIETARY_SUPPLEMENT: Fermented Velvet Antler extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomised Controlled Trial (RCT) to Evaluate Use of an Individual Auditory Cueing Device's (IACD's) on Freezing and Gait in People With Parkinson's Disease (PD)
Status: UNKNOWN
Conditions: Parkinson's Disease
Interventions: DEVICE: Auditory Cueing Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Post Breast Surgery Pain
Status: TERMINATED
Conditions: Breast Cancer
Interventions: PROCEDURE: Paravertebral block|PROCEDURE: Sham injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Pelvic Floor Muscle Training on Urinary Incontinence Reports in Obese Women Undergoing a Low Calorie Diet
Status: RECRUITING
Conditions: Urinary Incontinence|Obesity|Strength; Pelvic Floor
Interventions: OTHER: Pelvic Floor Muscle Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Digital Training Interventions for Low Back Pain
Status: RECRUITING
Conditions: Low Back Pain
Interventions: BEHAVIORAL: Supervised digital training with focus on core stability|BEHAVIORAL: Supervised digital training with focus on aerobic exercise|BEHAVIORAL: Non-supervised daily physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CT-G20 or CT-G11 and Food Effect of CT-G20 in Human Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CT-G11|DRUG: CT-G20|DRUG: CT-G11 Placebo|DRUG: CT-G20 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Nifecardia SRFC and Adalat OROS in the Treatment of Patients With Essential Hypertension
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: Nifedipine 30 mg GITS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Usefulness of Acetaminophen Associated With Strong Opioids for Acute Pain in Cancer Patients
Status: COMPLETED
Conditions: Acute Pain|Cancer Pain
Interventions: DRUG: Acetaminophen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LESS-TLH Versus LESS-LAVH
Status: COMPLETED
Conditions: Benign Uterine Disease
Interventions: PROCEDURE: LESS-TLH|PROCEDURE: LESS-LAVH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Analysis of Nutrient Absorption From a Novel Liposomal Multivitamin/Mineral Formulation
Status: COMPLETED
Conditions: Mineral Absorption
Interventions: DIETARY_SUPPLEMENT: Liposomal multivitamin/mineral|DIETARY_SUPPLEMENT: Standard multivitamin/mineral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Amyloidosis Incidence in High-Risk Cardiac Device Patients
Status: RECRUITING
Conditions: Amyloid|Cardiac Amyloidosis|Amyloidosis Cardiac|Systemic Amyloidosis|AL Amyloidosis|Infiltrative Cardiomyopathy, Amyloid|ATTR Amyloidosis Wild Type
Interventions: PROCEDURE: Chest Wall Fat Tissue Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Tamsulosin in the Treatment of Ureteral Stones
Status: COMPLETED
Conditions: Ureterolithiasis|Ureteral Calculi
Interventions: DRUG: Tamsulosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Gastrointestinal Cancer (Master Protocol) (Pegathor Gastrointestinal 203)
Status: ACTIVE_NOT_RECRUITING
Conditions: Oesophageal Squamous Cell Carcinoma|Gastric Cancer|Hepatocellular Carcinoma|Colorectal Cancer|Oesophageal Adenocarcinoma
Interventions: DRUG: THOR-707|DRUG: Pembrolizumab|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of mHealth for Serious Mental Illness
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Major Depressive Disorder|Bipolar Disorder
Interventions: OTHER: Smartphone App|OTHER: Waitlist Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of Urinary Neutrophil Gelatinase-Associated Lipocalin to Predict AKI in the NICU
Status: COMPLETED
Conditions: Acute Kidney Injury|Nephrotoxicity|Neonatal
Interventions: DIAGNOSTIC_TEST: urine neutrophil gelatinase -associated lipocalin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Absorbable Suture Versus Tissue Glue to Repair Defects Following Mohs Surgery
Status: COMPLETED
Conditions: Basal Cell Carcinoma|Squamous Cell Carcinoma
Interventions: DEVICE: Cyanoacrylate tissue glue versus Fast absorbing gut
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Internal Fixation Versus NonOperative Care With Early Rehabilitation for LC1 Fragility Fractures of the Pelvis
Status: NOT_YET_RECRUITING
Conditions: Multiple Closed Pelvic Fractures With Disruption of Pelvic Ring|Fragility Fracture|Internal Fixation|Nonoperative Care
Interventions: PROCEDURE: Early Internal Fixation|OTHER: Nonoperative Care with Early Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT