pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Trial of Hydrocortisone for Post-Traumatic Stress Disorder (PTSD)
Status: WITHDRAWN
Conditions: Post-traumatic Stress Disorder
Interventions: DRUG: Hydrocortisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Advanced HIV Disease Differentiated Care Model in Malawi
Status: ACTIVE_NOT_RECRUITING
Conditions: Opportunistic Infections, HIV-Related|Cryptococcal Infections|AIDS With Tuberculosis|AIDS-related Kaposi Sarcoma|AIDS and Infections
Interventions: OTHER: Enhanced package for AHD care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Digital Ischemia Reduction in Critically Ill Patients
Status: WITHDRAWN
Conditions: Hypovolemic Shock|Cardiogenic Shock|Digital Ischemia
Interventions: DEVICE: the combined use of vacuum assisted suction and heat exchanger warming
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Inhaled Nebulized Tobramycin in Non-cystic Fibrosis Bronchiectasis
Status: COMPLETED
Conditions: Non-CF Bronchiectasis
Interventions: DRUG: tobramycin inhalation solution|DRUG: Saline 0.9% inhalation solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acupoint Stimulation Improve Postoperative Delirium in Elderly Patients
Status: COMPLETED
Conditions: Postoperative Complications|Postoperative Delirium
Interventions: DEVICE: Transcutaneous acupoint electrical acupoint stimulation(TEAS) and auricular acupressure|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Functional Change and Efficacy of Duloxetine in Patients With Co-Morbid Depression & Soft Tissue Discomfort Syndrome
Status: COMPLETED
Conditions: Major Depressive Disorder|Soft Tissue Discomfort Syndrome|Pain
Interventions: DRUG: Duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Integrated Cardiovascular Health Education Program on Older Adults at Risk of ASCVD
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases|Healthy Lifestyle|Health Education
Interventions: BEHAVIORAL: HE programme|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mitochondrial Dysfunction in Type 2 Diabetes Mellitus and Capacity for Fat Oxidation During Exercise
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2|Overweight
Interventions: BEHAVIORAL: Aerobic exercise program - 8 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gut Imaging for Function & Transit in Cystic Fibrosis Study 2
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Tezacaftor/Ivacaftor + Ivacaftor|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study to Investigate the Safety and Tolerability of Intravenous QEQ278 in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung|Carcinoma, Renal Cell|Esophageal Squamous Cell Carcinoma|Squamous Cell Carcinoma of Head and Neck
Interventions: BIOLOGICAL: QEQ278
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Kinesio Taping and Manual Lymph Drainage on Pregnant Women With Restless Legs Syndrome
Status: RECRUITING
Conditions: Pregnancy|Restless Leg Syndrome|Nursing
Interventions: PROCEDURE: Kinesio Taping|PROCEDURE: Manual Lymph Drainage|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Implant Site Preparation With Piezosurgery vs Conventional Drills in Terms of Operation Time, Implant Stability and Bone Density
Status: COMPLETED
Conditions: Implant Osteotomy
Interventions: PROCEDURE: Piezosurgery assisted osteotomy|PROCEDURE: Conventional drilling osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: F-18 FES PET/CT in Measuring Hormone Expression in Patients With Primary, Recurrent, or Metastatic Breast Cancer Undergoing Endocrine-Targeted Therapy
Status: TERMINATED
Conditions: Estrogen Receptor Positive|Recurrent Breast Carcinoma|Stage IV Breast Cancer AJCC v6 and v7
Interventions: PROCEDURE: Computed Tomography|PROCEDURE: Computed Tomography|DRUG: F-18 16 Alpha-Fluoroestradiol|DRUG: Fludeoxyglucose F-18|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Positron Emission Tomography|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Susceptibility-weighted Magnetic Resonance Imaging and 4d-time-resolved Magnetic Resonance Angiography in Brain Arteriovenous Malformations
Status: UNKNOWN
Conditions: Arteriovenous Malformations
Interventions: DEVICE: MRI perfusion imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SuperNO2VA Et Versus Oxygen Face Mask During Deep Sedation
Status: COMPLETED
Conditions: Hypoxemia
Interventions: DEVICE: SuperNO2VA Et Nasal Positive Pressure Mask|DEVICE: Supplemental Oxygen Face Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dual Thrombolytic Therapy With Mutant Pro-urokinase and Low Dose Alteplase for Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DRUG: mutant pro-urokinase|DRUG: Alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventive VT Substrate Ablation in Ischemic Heart Disease
Status: RECRUITING
Conditions: Ventricular Tachycardia|Ventricular Arrythmia|Sudden Cardiac Death|Sudden Cardiac Death Due to Cardiac Arrhythmia|Ischemic Heart Disease|Myocardial Infarction|Magnetic Resonance Imaging
Interventions: PROCEDURE: Ventricular tachycardia substrate-based radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Multi-Level Remote Physical Activity Interventions in a National Sample of Older Women: The WHISH EnCore Trial
Status: RECRUITING
Conditions: Physical Inactivity
Interventions: BEHAVIORAL: PA Education plus human and planetary health information|BEHAVIORAL: PA Education plus Our Voice citizen science
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Home-based Transcranial Direct Current Stimulation for Pain Management in Persons With Alzheimer's Disease and Related Dementias
Status: COMPLETED
Conditions: Alzheimer's Disease and Related Dementias
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Structure and Function of the Retina in Adult Patients With Refractory Complex Partial Seizures Treated With Vigabatrin (Sabril®)
Status: COMPLETED
Conditions: Adult Refractory Complex Partial Seizures
Interventions: DRUG: Sabril
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Antibiotic Treatment for Reactive Arthritis Caused by Chlamydia Bacteria
Status: COMPLETED
Conditions: Arthritis, Reactive|Reiter Disease
Interventions: DRUG: Doxycycline and Rifampin|DRUG: Azithromycin and Rifampin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Asymptomatic HIV Infected Patients to Investigate Pharmacodynamics, Pharmacokinetics, Safety and Toleration of UK-453,061
Status: COMPLETED
Conditions: HIV-1
Interventions: DRUG: UK-453,061|DRUG: UK-453,061
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Colchicine in Hospitalized Colombian Patients With COVID-19
Status: TERMINATED
Conditions: Corona Virus Infection
Interventions: DRUG: Colchicine 0.5 MG|COMBINATION_PRODUCT: CONTROL GROUP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing The Effects Of Epoetin Hospira Single-Dose Vial (SDV) And Multi-Dose Vial (MDV) When Administered Subcutaneously To Normal Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Epoetin Hospira SDV|DRUG: Epoetin Hospira MDV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Fetal Aortic Valvuloplasty on Outcomes
Status: RECRUITING
Conditions: Congenital Heart Disease|Aortic Valve Stenosis|Fetal Cardiac Disorder|Hypoplastic Left Heart Syndrome
Interventions: PROCEDURE: Fetal aortic balloon dilatation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Induction Therapy With Autologous Mesenchymal Stem Cells for Kidney Allografts
Status: COMPLETED
Conditions: Renal Transplant Rejection
Interventions: PROCEDURE: Kidney transplantation with MSCs infusion|PROCEDURE: kidney transplantation without MSC infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NexGen TM Tibia Clinical Outcomes Study
Status: COMPLETED
Conditions: Osteoarthritis|Rheumatoid Arthritis|Traumatic Arthritis|Polyarthritis|Collagen Disorders and/or Avascular Necrosis of the Femoral Condyle|Post-traumatic Loss of Joint Configuration|Moderate Valgus, Varus, or Flexion Deformities
Interventions: DEVICE: NexGen TM Monoblock Tibia|DEVICE: NexGen TM Modular Tibia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of Brigatinib (AP26113) in Participants With Anaplastic Lymphoma Kinase (ALK)-Positive, Non-small Cell Lung Cancer (NSCLC) Previously Treated With Crizotinib
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Brigatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation on Immunogenicity and Safety Profile of Trivalent OPV (tOPV Bio Farma)
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: tOPV pilot batch|BIOLOGICAL: tOPV commercial batch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cryospray Therapy Versus Standard of Care for Benign Airway Stenosis (CryoStasis)
Status: RECRUITING
Conditions: Pulmonary Disease
Interventions: DEVICE: Spray cryotherapy|DEVICE: Ballon Dilation|DEVICE: Radial Incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Benefits of Perineural Versus Intravenous Dexamethasone in Patients Receiving Sciatic Nerve Block
Status: COMPLETED
Conditions: Fracture of Ankle
Interventions: DRUG: Dexamethasone|DRUG: Dexamethasone|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: FES PET/CT in Predicting Response in Patients With Newly Diagnosed Metastatic Breast Cancer Receiving Endocrine Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2/Neu Negative|Progesterone Receptor Negative|Progesterone Receptor Positive|Stage IV Breast Cancer AJCC v6 and v7
Interventions: PROCEDURE: Computed Tomography|DRUG: F-18 16 Alpha-Fluoroestradiol|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Onapristone and Anastrozole for the Treatment of Refractory Hormone Receptor Positive Endometrial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Refractory Endometrial Adenocarcinoma|Refractory Endometrial Carcinoma|Refractory Endometrial Clear Cell Adenocarcinoma|Refractory Endometrial Endometrioid Adenocarcinoma|Refractory Endometrial Mixed Cell Adenocarcinoma|Refractory Endometrial Serous Adenocarcinoma|Refractory Endometrial Undifferentiated Carcinoma
Interventions: DRUG: Extended-release Onapristone|DRUG: Anastrozole|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DIAGNOSTIC_TEST: Estrogen Receptor Positive (Positive Estrogen Receptor; ESR Positive; ESR1 Positive; ER Positive; Estrogen Receptor Alpha Positive)|DIAGNOSTIC_TEST: Progesterone Receptor Positive ( PGR Positive; PR Positive)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison Between Biological (Veritas®) vs Non Biological Mesh (TIGR®) in Immediate Breast Reconstruction
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: Veritas®|DEVICE: TIGR®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Octreotide and Doxorubicin in Treating Patients With Advanced Cancer
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: doxorubicin hydrochloride|DRUG: octreotide acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Retapamulin as a Decolonizing Agent for MRSA
Status: COMPLETED
Conditions: MRSA
Interventions: DRUG: Retapamulin|DRUG: Placebo Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention to Reduce Infectious Complications of Peritoneal Dialysis
Status: NOT_YET_RECRUITING
Conditions: Peritoneal Infection
Interventions: BEHAVIORAL: Intervention to reduce infectious complications of peritoneal dialysis|BEHAVIORAL: Data collection from the patient's clinical history
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Atezolizumab in Combination With Bevacizumab in Untreated Locally Advanced or Metastatic Clear Cell or Non-Clear Cell Renal Cell Carcinoma
Status: WITHDRAWN
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal rTMS for Cognitive Deficits and Negative Symptoms in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Negative Symptoms in Schizophrenia|Cognitive Impairment|Repetitive Transcranial Magnetic Stimulation|Dorsolateral Prefrontal Cortex
Interventions: DEVICE: Bilateral Active Repetitive transcranial magnetic stimulation (rTMS)|DEVICE: Left Active Repetitive transcranial magnetic stimulation (rTMS)|DEVICE: Sham rTMS over bilateral dorsolateral prefrontal cortex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral LBH589 in Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) and Mantle Cell Lymphoma (MCL)
Status: TERMINATED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: LBH589
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MGB/OAGB and LSG Effects on Lower Esophageal Sphincter (LES) Function
Status: UNKNOWN
Conditions: Morbid Obesity|Gastroesophageal Reflux|Bariatric Surgery Candidate
Interventions: PROCEDURE: MGB/OAGB|PROCEDURE: LSG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Acetylsalicylic Acid Compared With the Combination of Acetylsalicylic Acid + Modified-release Dipyridamole on Serum Thromboxane B2 Formation and Platelet Aggregation in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Asasantin®|DRUG: Acetylsalicylic acid low dose|DRUG: Acetylsalicylic acid high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Nephron Blockade vs. Dual Blockade Renin-angiotensin System + Bisoprolol in Resistant Arterial Hypertension
Status: COMPLETED
Conditions: Hypertension Resistant to Conventional Therapy
Interventions: DRUG: Spironolactone|DRUG: Furosemide,|DRUG: Amiloride|DRUG: Ramipril|DRUG: Bisoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Demineralized Dentin Allograft Versus Demineralized Dentin Autograft for Socket Preservation
Status: NOT_YET_RECRUITING
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: Demineralized Dentin Allograft|PROCEDURE: Demineralized Dentin Autograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuroplasticity in Parkinson´s Disease After Training
Status: COMPLETED
Conditions: Parkinson Disease|Physical Activity|Gait Disorders, Neurologic|Neural Degeneration
Interventions: BEHAVIORAL: HiBalance|BEHAVIORAL: Speech and communication therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cannabinoid Augmentation of Fear Response in Humans
Status: COMPLETED
Conditions: Fear Conditioning
Interventions: DRUG: PF-04457845|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: This Study Aimed to Examine the Effects of Individualized Care and Counseling Given to Mothers in the First Trimester of Pregnancy on Maternal Attachment, Maternal Self-efficacy and Maternal Function.
Status: NOT_YET_RECRUITING
Conditions: Maternal Behavior|Self Efficacy|Maternal Care Patterns
Interventions: OTHER: İndividualized care education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adoptive Transfer of Autologous T Cells Targeted to Prostate Specific Membrane Antigen (PSMA) for the Treatment of Castrate Metastatic Prostate Cancer (CMPC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: engineered autologous T cells|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of WA-NG (NG-IMT) Telescope Prosthesis in Patients With End-stage Age-related Macular Degeneration
Status: TERMINATED
Conditions: Age Related Macular Degeneration
Interventions: DEVICE: WA-NG (NG-IMT) Telescope Prothesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IIa Randomized Placebo Controlled Trial: Mesenchymal Stem Cells as a Disease-modifying Therapy for Idiopathic Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Mesenchymal Stem Cells|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Geriatric Assessment and Intervention in Older Patients Undergoing Surgery for Colorectal Cancer
Status: COMPLETED
Conditions: Colon Cancer|Colon Neoplasm|Frail Elderly Syndrome|Colorectal Cancer
Interventions: OTHER: Geriatric intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutrition Intervention to Measure Metabolic Response in Children
Status: COMPLETED
Conditions: Obesity, Childhood
Interventions: DIETARY_SUPPLEMENT: Control Breakfast Beverage|DIETARY_SUPPLEMENT: Omega-3 Breakfast Beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Thalidomide and Prednisone After Autologous Stem Cell Transplantation Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: prednisone|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relapse and Failure Rates Between CAD/CAM and Conventional Fixed Retainers
Status: COMPLETED
Conditions: Relapse
Interventions: OTHER: Computer Aided Design/ Computer Aided Manufacturing Retainers|OTHER: Lab-based Retainers|OTHER: Chairside Retainers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Safety of CS-1103 in Healthy Participants
Status: COMPLETED
Conditions: Substance Use Disorders|Methamphetamine Abuse|Methamphetamine Intoxication
Interventions: DRUG: CS-1103|DRUG: Sterile Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Uncooked Sweet Manioc Starch to Treat Hepatic Glycogen Storage Diseases
Status: COMPLETED
Conditions: Glycogen Storage Disease Type I
Interventions: DIETARY_SUPPLEMENT: Sweet manioc starch|DIETARY_SUPPLEMENT: Cornstarch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study: Safety and Efficacy of the Ulthera® System for Treatment of Axillary Hyperhidrosis
Status: COMPLETED
Conditions: Hyperhidrosis
Interventions: DRUG: Ulthera System Treatment|DRUG: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Device-assisted Practice of ADL on Arm/Hand Recovery in Individuals With Moderate to Severe Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: ReIn-Hand|DEVICE: Robot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of an Enhanced Rice Bran Nutritional Supplement in HIV
Status: COMPLETED
Conditions: Human Immunodeficiency Virus Infection
Interventions: DIETARY_SUPPLEMENT: rice bran arabinoxylan compound (RBAC)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I Safety and Pharmacokinetics Study of Microparticulate Atovaquone (m-Atovaquone; 566C80) in HIV-Infected and Perinatally Exposed Infants and Children
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Atovaquone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vedicitumomab Alone or in Combination for the Treatment of Locally Advanced or Metastatic SDC
Status: NOT_YET_RECRUITING
Conditions: Salivary Gland Cancer
Interventions: DRUG: vedicitumomab (Edisil, RC48）|DRUG: vedicitumomab in combination with pyrrolizidine|DRUG: RC48 in combination with a platinum-based chemotherapeutic agent|DRUG: RC48 in combination with teraplizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Tumor Tissue Samples From Younger Patients With Rhabdomyosarcoma
Status: COMPLETED
Conditions: Alveolar Childhood Rhabdomyosarcoma|Childhood Rhabdomyosarcoma|Embryonal Childhood Rhabdomyosarcoma
Interventions: OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Treatment of Type 2 Diabetes With an Insulin Infusion Pump
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2|Delivery Systems
Interventions: DEVICE: pump|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy & Lenalidomide in Newly Diagnosed Stage II-IV Peripheral T-cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Anaplastic Large Cell Lymphoma, ALK-Negative|Anaplastic Large Cell Lymphoma, ALK-Positive|Hepatosplenic T-Cell Lymphoma|Peripheral T-Cell Lymphoma, Not Otherwise Specified|Stage II Angioimmunoblastic T-cell Lymphoma|Stage II Enteropathy-Associated T-Cell Lymphoma|Stage III Angioimmunoblastic T-cell Lymphoma|Stage III Enteropathy-Associated T-Cell Lymphoma|Stage IV Angioimmunoblastic T-cell Lymphoma|Stage IV Enteropathy-Associated T-Cell Lymphoma
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Cyclophosphamide|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide|OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|PROCEDURE: Peripheral Blood Stem Cell Transplantation|DRUG: Prednisone|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Etoricoxib in Ear Nose Throat Surgery
Status: UNKNOWN
Conditions: Tonsillectomy
Interventions: DRUG: Administration of placebo|DRUG: Administration of etoricoxib|DRUG: Administration of etoricoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Montelukast and Loratadine in Children With Asthma
Status: COMPLETED
Conditions: Asthma in Children
Interventions: DRUG: Montelukast mixed with Loratadine|DRUG: Montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Metastatic or Unresectable Kidney Cancer
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|DRUG: methotrexate|DRUG: tacrolimus|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Vitamin D Supplementation in Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol|DIETARY_SUPPLEMENT: Miglyol oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Development and Polit Study of Get Ready With my Heart Program
Status: RECRUITING
Conditions: Transition to Adult Care|Congenital Heart Disease
Interventions: BEHAVIORAL: Get Ready with My Heart Program|BEHAVIORAL: Conventional intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Interaction Between Smoking, GCF Periostin, IL17A, IL17E and Non-surgical Periodontal Therapy
Status: COMPLETED
Conditions: Periodontitis|Smoking
Interventions: PROCEDURE: Non Surgical Periodontal Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hand Grasping Techniques on Eliciting the Grasp Reflex in Patients With Dementia
Status: COMPLETED
Conditions: Dementia
Interventions: OTHER: palmar grasp without dorsal stimulation|OTHER: standard palmar grasp test with dorsal stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Basket Trial for Combination Therapy With Durvalumab (Anti-PDL1) (MEDI4736) and Tremelimumab (Anti-CTLA4) in Patients With Metastatic Solid Tumors
Status: WITHDRAWN
Conditions: Metastatic Colorectal Cancer|Triple Negative Breast Cancer|Prostate Adenocarcinoma|Stomach Adenocarcinoma|Esophageal Adenocarcinoma
Interventions: DRUG: Tremelimumab|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of LMA-Proseal and Endobronchial Blocker for One Lung Anesthesia, Case Series
Status: COMPLETED
Conditions: Anesthetic Technique|One-lung Ventilation
Interventions: DEVICE: Bronchial blocker (Coopdech, Arndt)|DEVICE: LMA-ProsealTM
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Once Daily Tiotropium in Patients With Chronic Obstructive Pulmonary Disease (COPD) of Different Severity
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Moisture Management Liner At-Home Evaluation
Status: COMPLETED
Conditions: Amputation Stump|Amputation|Amputees|Lower Limb Deformity|Prosthesis User|Prosthesis
Interventions: DEVICE: Moisture Management Liner
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: INCMGA00012 in Patients With Previously Treated Unresectable or Metastatic Adenosquamous Pancreatic or Ampullary Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer Non-resectable|Pancreatic Cancer Metastatic
Interventions: DRUG: INCMGA00012 (PD-1 antibody)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Primary Care, EHR- Based Strategy to Promote Safe and Appropriate Drug Use
Status: COMPLETED
Conditions: Diabetes Mellitus Type I|Diabetes Mellitus Type II
Interventions: OTHER: EHR Based Strategy to promote Safe and Appropriate Drug Use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Docetaxel or Abiraterone Acetate With ADT in Treating Patients With Metastatic Hormone Sensitive Prostate Cancer
Status: TERMINATED
Conditions: Castration-Sensitive Prostate Carcinoma|Metastatic Prostatic Adenocarcinoma|Stage IV Prostate Cancer|Stage IVA Prostate Cancer|Stage IVB Prostate Cancer
Interventions: DRUG: Abiraterone Acetate|DRUG: Antiandrogen Therapy|DRUG: Docetaxel|DRUG: Prednisone|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nebulized Budesonide for Children Who Are Hospitalized for Acute Wheezing
Status: COMPLETED
Conditions: Asthma|Acute Asthma
Interventions: DRUG: Budesonide 0.5 mg/ml nebules|DRUG: % 0.9 Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Function Following Laser for Anal Intraepithelial Neoplasia (FLAN)
Status: UNKNOWN
Conditions: Anus Cancer|Fecal Incontinence|Anal Intraepithelial Neoplasia|Post Operative Pain
Interventions: PROCEDURE: high resolution anal manometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Assess Efficacy of Artemether-lumefantrine Prophylaxis Against Forest Malaria in Cambodia (PAL_Cambodia)
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Artemether-lumefantrine|DIETARY_SUPPLEMENT: Multivitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Increased Microcirculation for Preventing Postoperative Wound Infections in Patients Undergoing Reduction Mammoplasty
Status: COMPLETED
Conditions: Surgical Side Infections After Breast Reduction
Interventions: DRUG: 250ml HES 6%|DRUG: 9% NaCl 500ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SEGMENTAL AND GENERAL STABILIZATION EXERCISES IN CHRONIC LOW BACK PAIN
Status: COMPLETED
Conditions: Segmental Stabilization|Generalized Segmental Stabilization Exercises
Interventions: OTHER: Segmental stabilization|OTHER: Generalized Lumber stabilization exercsies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy With BCMA CAR-T Cells in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: BCMA CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of TQB3728 Tablets in Sequential Maintenance of TQB2450 Injection Therapy in Patients After Sequential or Concurrent Chemoradiation for Locally Advanced Non-small Cell Lung Cancer.
Status: NOT_YET_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: COMBINATION_PRODUCT: TQB3728 tablets, TQB2450 injection, sequential or concurrent chemoradiation|COMBINATION_PRODUCT: TQB3728 tablets, TQB2450 injection, sequential or concurrent chemoradiation|COMBINATION_PRODUCT: TQB2450 injection, sequential or concurrent chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Single Doses of Liraglutide and Dapagliflozin on Ketogenesis in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Victoza|DRUG: Placebo|DRUG: Dapagliflozin 10mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II/Pharmacodynamic Study of Hydroxychloroquine in Combination With Gemcitabine/Abraxane to Inhibit Autophagy in Pancreatic Cancer
Status: COMPLETED
Conditions: Advanced Adenocarcinoma|Metastatic Adenocarcinoma
Interventions: DRUG: Hydroxychloroquine (HCQ)|DRUG: Gemcitabine|DRUG: Abraxane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmethylphenidate Hydrochloride Tablets Under Non-Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dexmethylphenidate Hydrochloride|DRUG: Dexmethylphenidate Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sleep Inducing And Maintaining Efficacy Of Circadin In Elderly Insomniacs
Status: COMPLETED
Conditions: Primary Insomnia
Interventions: DRUG: placebo Circadin|DRUG: Circadin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Feasibility Trial of the Family Strengthening Intervention in Rwanda (FSI-R)
Status: COMPLETED
Conditions: Depressive Symptoms|Anxiety|Parenting
Interventions: BEHAVIORAL: Family Strengthening Intervention in Rwanda (FSI-R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study to Assess Nominal Versus Controlled Stimuli on Dentinal Hypersensitivity
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: DEVICE: Crest® Sensi-Stop™ Strips
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Interaction Between Immunosuppressive Drugs and Protein-bound Uremic Toxins in Renal Transplant Patients
Status: WITHDRAWN
Conditions: Kidney Transplant|Immunosuppression|Uremic; Toxemia
Interventions: OTHER: calcineurin inhibitor dosage
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Real-Time Feedback Assisted Self-Correction on the Posture of Scoliotic Patients
Status: UNKNOWN
Conditions: Idiopathic Scoliosis
Interventions: DEVICE: Night-time brace + virtual-brace|OTHER: Night-time brace only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Survival Outcomes of Total Thyroidectomy and Radioactive Iodine Therapy in Unilateral T3/T4 FTC
Status: COMPLETED
Conditions: Follicular Thyroid Cancer|SEER Database Analysis
Interventions: PROCEDURE: Total Thyroidectomy (TT)|RADIATION: Radioactive iodine treatment(RAIT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Intensive cART During Acute/Early HIV Infection
Status: COMPLETED
Conditions: Acute HIV Infection
Interventions: DRUG: raltegravir|DRUG: maraviroc|DRUG: emtricitabine 200mg /tenofovir 300mg|DRUG: lopinavir 400 mg/ritonavir 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vinorelbine and Celecoxib in Treating Women With Relapsed or Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: celecoxib|DRUG: vinorelbine ditartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Two Centre Study to Assess the Stability and Long-term Performance of the C-Stem™ AMT in a Total Primary Hip Replacement
Status: TERMINATED
Conditions: Rheumatoid Arthritis|Osteoarthritis|Post-traumatic Arthritis|Collagen Disorders|Avascular Necrosis|Traumatic Femoral Fractures|Nonunion of Femoral Fractures|Congenital Hip Dysplasia|Slipped Capital Femoral Epiphysis
Interventions: DEVICE: C-Stem™ AMT Femoral Component (standard and high off-set variants)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Safety of SPA100 (Fixed-dose Combination of Aliskiren/Amlodipine) in Patients With Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Ali/Amlo 150/2.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Epidural Local Anesthetics on Propofol Induction
Status: COMPLETED
Conditions: General Anesthesia|Propofol Target-controlled Infusion|Thoracic Epidural Anesthesia
Interventions: DRUG: Lidocaine|DRUG: Bupivacaine|DRUG: Ropivacaine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Placebo-controlled Trial Evaluating the Efficacy of Antroquinonol in Patients With Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DRUG: Antroquinonol Capsule 50mg|DRUG: Antroquinonol Capsule 100mg|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial Evaluating the Efficacy of Palbociclib in Combination With Carboplatin for the Treatment of Unresectable Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Palbociclib|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of N-3 Polyunsaturated Fatty Acids On Chylomicron Secretion And Expression Of Genes That Regulate Intestinal Lipid Metabolism In Men With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: n-3 PUFAs|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cemiplimab-rwlc for Unresectable Locally Recurrent and/or Metastatic CSCC
Status: TERMINATED
Conditions: Cutaneous Squamous Cell Carcinoma|Cutaneous Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Cemiplimab-Rwlc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study to Evaluate the Efficacy and Safety of TNX-102 SL in Participants With PTSD
Status: TERMINATED
Conditions: PTSD
Interventions: DRUG: TNX-102 SL|DRUG: Placebo SL Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Atraumatic Restorative Treatment and Oral Health Promotion on Psychological and Salivary Aspects of Children
Status: COMPLETED
Conditions: Dental Caries
Interventions: OTHER: Oral health educational strategy|PROCEDURE: Atraumatic Restorative Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Truenat™ HCV RNA Assay Evaluation
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DEVICE: Molbio Truenat™ HCV assay (the investigational product)|OTHER: Abbott RealTime HCV assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: LCL161 Plus Topotecan for Patients With Relapsed/Refractory Small Cell Lung Cancer and Select Gynecologic Malignancies
Status: TERMINATED
Conditions: Small Cell Lung Cancer|Ovarian Cancer
Interventions: DRUG: LCL161|DRUG: Topotecan|DRUG: Pegylated GCSF (PEG-GCSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Atorvastatin in Combination With Radiotherapy and Temozolomide in Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Atorvastatin|DRUG: Temozolomide|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma
Status: RECRUITING
Conditions: Mesothelioma|Malignant Mesothelioma (MM)|Early-stage Mesothelioma|Subclinical Mesothelioma|BRCA1-Associated Protein-1 (BAP1) Mutations|Early-stage BAP1-associated Malignancies
Interventions: DRUG: Decitabine/cedazuridine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Danish Childhood Obesity Biobank
Status: RECRUITING
Conditions: Obesity|Metabolic Disease|NAFLD, Non-alcoholic Fatty Liver Disease|Cardiovascular Diseases
Interventions: BEHAVIORAL: A family-centered, multidisciplinary obesity treatment program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Electric Wheelchair Driving Performance in Simulator Compared to Driving in Real-life Situations
Status: COMPLETED
Conditions: Neurologic Disorder
Interventions: DEVICE: Driving an electric wheelchair in real condition|DEVICE: Driving an electric wheelchair in virtual condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Topical Ruxolitinib Evaluation in Vitiligo Study 2 (TRuE-V2)
Status: COMPLETED
Conditions: Non-segmental Vitiligo
Interventions: DRUG: Ruxolitinib cream|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT