pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Rolapitant Hydrochloride in Preventing Nausea/Vomiting in Patients With Sarcoma Receiving Chemotherapy
Status: TERMINATED
Conditions: Locally Advanced Sarcoma
Interventions: DRUG: Dexamethasone|DRUG: Doxorubicin|DRUG: Fosaprepitant Dimeglumine|DRUG: Ifosfamide|OTHER: Laboratory Biomarker Analysis|DRUG: Mesna|DRUG: Ondansetron|OTHER: Questionnaire Administration|DRUG: Rolapitant Hydrochloride|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CD19-targeted CAR T Cells for Relapsed and Refractory (R/R) Non-Hodgkins Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma, Non-Hodgkin|Diffuse Large B Cell Lymphoma|Follicular Lymphoma
Interventions: BIOLOGICAL: CD19-targeted Chimeric Antigen Receptor (CAR) T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Effervescent Alendronate on Bone Turnover
Status: COMPLETED
Conditions: Osteopenia or Osteoporosis
Interventions: DRUG: Conventional alendronate|DRUG: Effervescent and buffered alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted Vs Generic Print Materials on Physical Activity and Quality of Life in Young Adult Cancer Survivors
Status: COMPLETED
Conditions: Behaviour Change
Interventions: BEHAVIORAL: Stride to Survive:An Exercise Guide for Young Adult Cancer Survivors|BEHAVIORAL: Canadian Physical Activity Guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prothrombotic Inflammatory Markers in Women With Metabolic Syndrome - Effect of Atorvastatin
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DRUG: Atorvastatin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reverse Prediction of Ion Channel Remodeling in Patients With Atrial Fibrillation Utilizing Monophasic Action Potential and Mathematical Modeling
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Monophasic action potential(MAP) catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Does Sleep Quality Change After Switch From Wellbutrin SR to Wellbutrin XL in Patients With Major Depressive Disorder?
Status: COMPLETED
Conditions: Mood Disorder
Interventions: DRUG: Wellbutrin XL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavior Therapy for Depression, Stigmatization, Criminogenic Cognition, and Quality of Life Among Patients With Opioid Use Disorder (OUD): A Randomized Control Trial.
Status: ACTIVE_NOT_RECRUITING
Conditions: Psychoeducation
Interventions: BEHAVIORAL: psychoeducation|BEHAVIORAL: Stigma Reduction and Relapse Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ametop Compared to Ametop With Pain Ease Spray
Status: UNKNOWN
Conditions: Analgesia|Topical Anesthetic
Interventions: DEVICE: Pain Ease Cold Spray|DRUG: Ametop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Delayed Renal Allograft Function and Furosemide Treatment
Status: WITHDRAWN
Conditions: Delayed Graft Function
Interventions: DRUG: Furosemide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Study of BG00012 in Pediatric Subjects With Relapsing Remitting Multiple Sclerosis (RRMS)
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: dimethyl fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Volunteer Comfort for Transcranial Electrical Stimulation (TES): An Assessment
Status: ENROLLING_BY_INVITATION
Conditions: Performance Enhancing Product Use|Sleep
Interventions: DEVICE: transcranial electric stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Non-invasive Brain Stimulation on Learning Novel Spoken Words
Status: RECRUITING
Conditions: Dyslexia|Dyslexia, Developmental|Learning; Developmental Disorder, Reading
Interventions: OTHER: Active cTBS|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetics of Nebulized Amikacin in Patients With Pneumonia Undergoing Mechanical Ventilation
Status: UNKNOWN
Conditions: Ventilator Associated Pneumonia
Interventions: DRUG: Nebulized amikacin|DRUG: Intravenous amikacin|DRUG: Placebo nebulization|DRUG: Placebo infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quadratus Lumborum Nerve Blocks for Myomectomies
Status: TERMINATED
Conditions: Laparoscopic Myomectomy|Quadratus Lumborum Nerve Block
Interventions: DRUG: Ropivacaine injection|PROCEDURE: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and PK of a Single IM Dose of G03-52-01 vs Placebo in Adult Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: DRUG: G03-52-01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy, Radiation Therapy, and Bevacizumab in Treating Patients With Newly Diagnosed Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Adenocarcinoma|Lung Adenosquamous Carcinoma|Lung Large Cell Carcinoma|Lung Squamous Cell Carcinoma|Minimally Invasive Lung Adenocarcinoma|Stage IIIA Lung Non-Small Cell Cancer AJCC v7|Stage IIIB Lung Non-Small Cell Cancer AJCC v7
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Cisplatin|DRUG: Docetaxel|DRUG: Etoposide|BIOLOGICAL: Filgrastim|BIOLOGICAL: Pegfilgrastim|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buprenorphine Accumulation and Description of Its Metabolites During Co-Medication of Buprenorphine Transdermal System (BTDS) and Ketoconazole
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Buprenorphine transdermal patch|DRUG: Ketoconazole tablet|DRUG: Placebo to match ketoconazole tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Surufatinib Combined With Tislelizumab in Advanced Lung Cancer With Neuroendocrine Differentiation
Status: NOT_YET_RECRUITING
Conditions: NSCLC
Interventions: DRUG: Surufatinib|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin + Radiotherapy vs Durvalumab + Radiotherapy Followed by Durvalumab vs Durvalumab + Radiotherapy Followed by Tremelimumab + Durvalumab in Intermediate-Risk HPV-Positive Oropharyngeal SCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Oropharyngeal Squamous Cell Carcinoma
Interventions: RADIATION: Radiation|DRUG: Cisplatin|DRUG: Durvalumab|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Phase II Study of SR-T100 to Treat Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Vehicle gel|DRUG: SR-T100 with 2.3% of SM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Tesomet With Open-label Extension in Subjects With Hypothalamic Obesity (HO)
Status: WITHDRAWN
Conditions: Hypothalamic Obesity
Interventions: OTHER: Placebo|DRUG: Tesomet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Self-compassion and Treatment Adherence in Schizophrenic Spectrum Disorders
Status: WITHDRAWN
Conditions: Treatment Adherence|Selfcompassion|Schizophrenic Spectrum Disorder
Interventions: OTHER: questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Emtricitabine for Prevention of Vertical Transmission of HBV in Chinese Pregnant HBsAg Positive Patients
Status: UNKNOWN
Conditions: Hepatitis B, Chronic|Pregnancy
Interventions: DRUG: Emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Efficacy, and Pharmacokinetic Behavior of Leuprolide Mesylate in Subjects With Advanced Prostate Carcinoma
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Leuprolide Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Withdrawal of Etanercept After Successful Treatment of Juvenile Idiopathic Arthritis
Status: UNKNOWN
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: etanercept|DRUG: etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atomoxetine and DAW2022 on OSA Severity
Status: RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Placebo oral capsule|DRUG: Atomoxetine Oral Capsule [Strattera]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: No Axillary sUrgical Treatment In Clinically Lymph Node Negative Patients After UltraSonography
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Sentinel Lymph Node
Interventions: PROCEDURE: No SLNB|PROCEDURE: SLNB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: External vs Internal-triggered Augmented-reality Visual Cues to Treat Freezing of Gait
Status: COMPLETED
Conditions: Parkinson Disease|Gait Disorders, Neurologic|Parkinsonian Disorders|Movement Disorders|Gait, Unsteady|Gait, Festinating
Interventions: OTHER: No Cue|OTHER: Conventional Cue|OTHER: Constant Cue|OTHER: Patient hand-triggered|OTHER: Patient eye-triggered|OTHER: Examiner-triggered
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Magnetic Resonance GUIDEd Management of Mild-moderate Left Ventricular Systolic Dysfunction.
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure|Left Ventricular Systolic Dysfunction
Interventions: DEVICE: ICD|DEVICE: ILR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vaccine Therapy and GM-CSF With or Without Low-Dose Aldesleukin in Treating Patients With Stage II, Stage III, or Stage IV Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: MART-1 antigen|BIOLOGICAL: IL-2|BIOLOGICAL: gp100 antigen|BIOLOGICAL: GM-CSF|BIOLOGICAL: MART-1a peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Alternative Technique for Lumbar Medial Branch Radiofrequency: Comparison With the Empirical Technique
Status: UNKNOWN
Conditions: Low Back Pain|Lumbar Facet Joint Pain|Arthropathy
Interventions: PROCEDURE: lumbar medial branch radiofrequency neurotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of a Mouth and Throat Rinse for the Treatment of Acute Sore Throat
Status: RECRUITING
Conditions: Sore-throat|Upper Respiratory Infection
Interventions: DEVICE: Verum (WO 6607)|DEVICE: Placebo (WO 6608)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of an Equimolar Mixture of Oxygen and Nitrous Oxide in External Cephalic Version (ECV)
Status: COMPLETED
Conditions: Breech Presentation in Pregnancy
Interventions: DRUG: equimolar mixture of oxygen and nitrous oxide or medical air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Conventional and Patient-specific Instrumentation in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Total Knee Arthroplasty with use of Visionaire Patient-Specific Instrumentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of IM19 CAR-T Cells in Patients With Relapsed and Refractory (R/R) Mantle Cell Lymphoma
Status: UNKNOWN
Conditions: Lymphoma|Lymphoma, Mantle-Cell|Neoplasms by Histologic Type|Neoplasms|Lymphoproliferative Disorders
Interventions: BIOLOGICAL: IM19 CAR-T cells|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjusted Brodalumab Dose Compared With Standard Brodalumab Dose in Subjects With Moderate-to-severe Plaque Psoriasis and ≥120 kg Body Weight
Status: RECRUITING
Conditions: Psoriasis Vulgaris
Interventions: BIOLOGICAL: Brodalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial Investigating Every Other Day Dosing of Oral Iron in Premature Infants (IQONic)
Status: RECRUITING
Conditions: Very Low Birth Weight Infant|Premature Infants|Anemia of Prematurity|Iron Deficiency, Anaemia in Children|Extremely Low Birth Weight
Interventions: DIETARY_SUPPLEMENT: 6 mg/kg of oral iron as ferrous sulfate administered every other day.|DIETARY_SUPPLEMENT: 6 mg/kg of oral iron as ferrous sulfate administered every day.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A-Health RCT: Effects of Participatory Art-based Activity on Health of Older Community Dwellers
Status: COMPLETED
Conditions: Social Interaction|Quality of Life|Health, Subjective
Interventions: OTHER: participatory art-based activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Safety and Efficacy of the VRC01 Antibody in Reducing Acquisition of HIV-1 Infection in Women
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: VRC01|BIOLOGICAL: Placebo for VRC01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Effects of a Nutritional Intervention of Ketogenic Medium-chain Triglycerides and B-vitamins on Cognitive Functioning in Older Adults With Mild Cognitive Impairment (COGNIKET-MCI)
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: BrainXpert|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect Of Open And Closed System Peripheral Catheters Used In Pediatric Services
Status: COMPLETED
Conditions: Child, Only|Catheter Infection|Catheter Complications
Interventions: OTHER: Closed-system catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Safety and Efficacy of Docetaxel for Injection (Albumin-bound)in Different Dose Regimens in Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Solid Tumors
Interventions: DRUG: Albumin-bound docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effectiveness and Safety of 2 Dosage Regimens of Oral Fidrisertib (IPN60130) for the Treatment of Fibrodysplasia Ossificans Progressiva (FOP).
Status: RECRUITING
Conditions: Fibrodysplasia Ossificans Progressiva
Interventions: DRUG: IPN60130|DRUG: IPN60130|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Pharmacokinetic Interaction Between 2 Direct Acting Antiviral Agents Odalasvir and AL-335 and Between 3 Direct Acting Antiviral Agents Simeprevir, Odalasvir and AL-335 at Steady State in Healthy Japanese Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AL-335|DRUG: Odalasvir (ODV)|DRUG: Simeprevir (SMV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimized Antibiotic Therapy in Patients With Subarachnoid Haemorrhage (ES) and Cerebral Haemorrhage (EC)
Status: UNKNOWN
Conditions: Therapeutic Drug Monitoring|Subarachnoid Hemorrhage|Intracerebral Hemorrhage
Interventions: DRUG: Piperacillin/tazobactam|DRUG: Meropenem|DRUG: Daptomycin|DRUG: Ceftobiprole|DRUG: Linezolid|DRUG: Vancomycin|DRUG: Fluconazol|DRUG: Acyclovir|DRUG: Gentamicins|DRUG: Amikacin|DRUG: Ganciclovir
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Outcomes Between Early Physical Therapy Intervention and Usual Care Following Anterior Cervical Fusion Surgery
Status: COMPLETED
Conditions: Cervical Spine Degenerative Disc Disease|Fusion of Spine, Cervical Region
Interventions: OTHER: early physical therapy intervention|OTHER: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Caffeine in Elderly Citizen Following Eight Hour Abstinence From Caffeine Containing Drinks & Foods
Status: COMPLETED
Conditions: Healthy|Elderly
Interventions: DRUG: Caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CopenHeart IE - Integrated Rehabilitation of Patients Treated for Infective Endocarditis
Status: COMPLETED
Conditions: Infective Endocarditis
Interventions: OTHER: Complex Cardiac rehabilitation|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: AI-Assisted Treatment for Residual Speech Sound Disorders
Status: RECRUITING
Conditions: Speech Sound Disorder
Interventions: BEHAVIORAL: Speech-Language Pathologist-led Speech Motor Chaining|BEHAVIORAL: Artificial Intelligence-led Speech Motor Chaining (CHAINING-AI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vollure for the Correction of Atrophic Facial Scarring
Status: UNKNOWN
Conditions: Atrophic Scar
Interventions: DEVICE: Allergan Vollure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Org 24448 (Ampakine) for Cognitive Deficits in Schizophrenia
Status: WITHDRAWN
Conditions: Schizophrenia
Interventions: DRUG: Org 24448|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Rho-kinase Inhibitor (Fasudil) in the Treatment of Raynaud's Phenomenon
Status: COMPLETED
Conditions: Raynaud|Scleroderma
Interventions: DRUG: Fasudil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Changes in Ischemia and Angina Over 1 Year Among ISCHEMIA Trial Screen Failures With no Obstructive CAD on Coronary CT Angiography
Status: COMPLETED
Conditions: Microvascular Angina|Angina Pectoris
Interventions: OTHER: Quality of Life assessment|PROCEDURE: Stress imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: LIAISON NES Influenza (FLU) A/B & Coronavirus Disease 2019 (COVID-19) Clinical Agreement in Australia
Status: COMPLETED
Conditions: Influenza A|Influenza Type B|Coronavirus Disease 2019
Interventions: DIAGNOSTIC_TEST: LIAISON NES FLU A/B & COVID-19
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Directional Stimulation During the Implantation of Deep Brain Stimulation (DBS) Leads
Status: COMPLETED
Conditions: Parkinson's Disease|Essential Tremor
Interventions: DEVICE: directSTN Acute lead connected to external neurostimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Pembrolizumab, Lenvatinib and Chemotherapy Combination in First Line Extensive-stage Small Cell Lung Cancer
Status: RECRUITING
Conditions: Small Cell Lung Cancer Extensive Stage
Interventions: DRUG: Lenvatinib|DRUG: Pembrolizumab|DRUG: Etoposide|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models
Status: RECRUITING
Conditions: Inherited Retinal Dystrophy|Retinitis Pigmentosa|Macular Dystrophy
Interventions: DIAGNOSTIC_TEST: whole genome sequencing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Abatacept Combined With JAK Inhibitor for Refractory Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Abatacept|Treatment Compliance|Rheumatoid Arthritis
Interventions: DRUG: Janus Kinase Inhibitor|DRUG: Abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cardiac Resynchronization Therapy (CRT) on Skeletal Muscle Histology, Neuroendocrine Activation and Inflammatory Response
Status: COMPLETED
Conditions: Skeletal Muscle Changes After Crt
Interventions: DEVICE: CRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Transcranial Magnetic Stimulation In Patients With Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Active Repetitive Transcranial Magnetic Stimulation Therapy|DEVICE: Active Continuous Theta Burst Stimulation Therapy|DEVICE: Sham Continuous Theta Burst Stimulation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of NPSP558 in the Treatment of Hypoparathyroidism
Status: COMPLETED
Conditions: Hypoparathyroidism
Interventions: DRUG: Placebo|DRUG: NPSP558
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention Study of an Individualized Exergame Training for People With Major Neurocognitive Disorder
Status: UNKNOWN
Conditions: Exergame|Major Neurocognitive Disorder|Long-term Care Facility|Nursing Home
Interventions: DEVICE: Motor-cognitive training device|OTHER: Active control condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetic Evaluation of Nitrite for Prevention of Cerebral Vasospasm
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage
Interventions: DRUG: Sodium nitrite|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of HM10760A (Long-acting Erythropoietin) in Healthy Adult Caucasian and Japanese Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HM10760A or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Immunotherapy (Sasanlimab) in Combination With Targeted Therapies in People With Advanced Non-small Cell Lung Cancer (NSCLC) (Landscape 1011 Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Sasanlimab Prefilled syringe|DRUG: Encorafenib|DRUG: Binimetinib|DRUG: Sasanlimab|DRUG: Axitinib|DRUG: SEA-TGT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Lactate Ingestion on Appetite Regulation
Status: NOT_YET_RECRUITING
Conditions: Appetitive Behavior
Interventions: OTHER: Sodium Lactate|OTHER: Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Exercise Benefits to Promote Health Aging Among Chronically Ill Geriatrics in a Community
Status: COMPLETED
Conditions: Diabetes|Hypertension|Osteoporosis|Osteoarthritis
Interventions: DEVICE: hydraulic resistance circuit training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Treatment of Type 2 Diabetes Mellitus by Duodenal Exclusion Associated With Omentectomy: Clinical and Hormonal Study
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2|Insulin Resistance|Obesity
Interventions: PROCEDURE: Duodenal exclusion plus omentectomy|PROCEDURE: Duodenal exclusion without omentectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Validity and Utility of Genomic-targeted Chemoprevention of PCa: Aim 4a
Status: COMPLETED
Conditions: Prostate Cancer|Prostate Cancer, Familial|Hereditary Prostate Cancer
Interventions: GENETIC: Genetic Risk Score: Number Format|GENETIC: Genetic Risk Score: Number + Pictograph|BEHAVIORAL: Family History: Number Format|BEHAVIORAL: Family History: Number + Pictograph
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dinoprostone Versus Vaginal Misoprostol for Induction of Labour
Status: COMPLETED
Conditions: Induced Vaginal Delivery
Interventions: DRUG: Vaginal Dinoprostone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Zinc Fortified Fermented Wheat Flour
Status: COMPLETED
Conditions: Malnutrition|Diabetes|Inflammation|Conjunctivitis
Interventions: DIETARY_SUPPLEMENT: Fermented High Zinc Wheat Flour Flatbread|DIETARY_SUPPLEMENT: Unfermented High Zinc Wheat Flour Flatbread|DIETARY_SUPPLEMENT: Post-Harvest Fortified Whole Wheat Flour Flatbread|DIETARY_SUPPLEMENT: Low Zinc Whole Wheat Flour Flatbread (Control Group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficiency Comparison Between Methylprednisolone and Phenol 8% Treatment Using a Trans Sacral Approach - on Lower Back Pain and Limbs
Status: UNKNOWN
Conditions: Back Pain
Interventions: DRUG: phenol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Ingavirin® 90 mg Once Daily to Treat Influenza and Other Acute Viral Infections in Adults
Status: COMPLETED
Conditions: Common Cold|Influenza, Human|Acute Respiratory Infection
Interventions: DRUG: Ingavirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ceftolozane/Tazobactam Versus Meropenem for Febrile Neutropenia on Patients Colonized With or at Risk for Infection With Extended Spectrum Beta Lactamase - Producing Pathogens
Status: NOT_YET_RECRUITING
Conditions: Febrile Neutropenia
Interventions: DRUG: Ceftolozane-Tazobactam|DRUG: Meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capsaicin Nanoparticle in Patient With Painful Diabetic Neuropathy
Status: UNKNOWN
Conditions: Painful Diabetic Neuropathy
Interventions: DRUG: 0.75% capsaicin nanoparticle cream|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comprehensive HIV Prevention Package for MSM in Southern Africa: Pilot Study (Sibanye Health Project)
Status: COMPLETED
Conditions: HIV
Interventions: BEHAVIORAL: Condom choices|BEHAVIORAL: Condom-compatible lubricant choices|BEHAVIORAL: Couples HIV counseling and testing (CVCT)|DRUG: Pre-exposure prophylaxis with FTC/TDF|OTHER: Staff and provider MSM and LGBT sensitization training|BEHAVIORAL: HIV Testing and Risk-reduction counseling|BEHAVIORAL: Linkage to care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Empiric Levothyroxine (LT4) Dose Increase Versus Individualized LT4 Dose Increase in Hypothyroid Women During Pregnancy
Status: COMPLETED
Conditions: Pregnancy Related|Thyroid
Interventions: DRUG: levothyroxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Oxytocin's Effects on Attention Control
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Oral Oxytocin|DRUG: Oral Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficiency of Deep Transcranial Magnetic Stimulation on Patients With Mild Cognitive Impairment
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: H-Coil Deep TMS|DEVICE: SHAM Coil TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Optimization of a Photoretinoscopy Method for Determining the Objective Refraction of Children With a Smartphone/add-on Device in India
Status: NOT_YET_RECRUITING
Conditions: Ametropia
Interventions: DEVICE: Comparator device, Closed-field autorefractometer without cycloplegia|OTHER: Distance visual acuity check using objective refraction without cycloplegia|DEVICE: Comparator device, Closed-field autorefractometer with cycloplegia|OTHER: Distance visual acuity check using objective refraction with cycloplegia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study of CTA101 UCAR-T Cell Injection in Patients With Relapsed or Refractory CD19+ B-line Hematological Malignancy
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Non-hodgkin Lymphoma
Interventions: DRUG: CTA101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bacteriology of sUrGical Site INfection Following Surgery for Intestinal Failure
Status: COMPLETED
Conditions: Surgical Wound Infection|Surgical Site Infection|Bacteria Infection Mechanism|Intestinal Disease|Intestinal Fistula
Interventions: DIAGNOSTIC_TEST: Microbiology swab|OTHER: Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevalence of the c.853delT Mutation of the HOXB13 Gene in Prostate Cancer in Martinique
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: GENETIC: HOXB13 c.853delT mutation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effect On Paın And Anxıety Of Stress Ball Use Durıng Sharp Debrıdement
Status: RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: OTHER: In Patıents Wıth Dıabetıc Foot Ulcer, Effect On Paın And Anxıety Of Stress Ball Use Durıng Sharp Debrıdement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: To Study the Safety and Efficacy of Simvastatin in Patients With Hepatopulmonary Syndrome in Cirrhosis.
Status: UNKNOWN
Conditions: Liver Cirrhosis
Interventions: DRUG: Simvastatin 40mg|OTHER: Placebo|OTHER: Standard medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-traumatic Stress Disorder (PTSD), Addiction, and Virtual Reality
Status: COMPLETED
Conditions: Substance Use Disorders|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Prolonged Exposure Therapy|BEHAVIORAL: Prolonged Exposure therapy + VR/ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Music on the Anxiety and Sleep Quality of Pregnant Women on Bed Rest for a High-risk Pregnancy
Status: COMPLETED
Conditions: Pregnancy, High Risk|Anxiety State|Sleep Quality
Interventions: OTHER: Acemaşiran Music Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Alisertib in Combination With Osimertinib in Metastatic EGFR-mutant Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer Metastatic|EGFR Gene Mutation
Interventions: DRUG: Osimertinib|DRUG: Alisertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Galantamine on the Attention and the Frontal Function of the Patients With Dementia of Alzheimer Type
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: galantamine hydrobromide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Ultrasound Guided Supraclavicular and Infraclavicular Subclavian Venous Catheterizations in Adult Patients Undergoing Major Surgeries
Status: COMPLETED
Conditions: Compare Central Line Insertion of Subclavian Vein With Two Different Approaches Using Ultrasound
Interventions: PROCEDURE: ultrasound guided central venous cannulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Aesthetic Analysis of Gluteal Deformity After Weight Loss and Assessment the Role of Autologous Tissue Augmentation for Gluteal Contouring
Status: UNKNOWN
Conditions: Body Contouring
Interventions: PROCEDURE: superior gluteal artery flap and lumbar artery falp|PROCEDURE: The gluteal pocket|PROCEDURE: infragluteal dermal lifiting flap
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Comparative Study Between ABP 501 and Humira® in Participants With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Adalimumab|DRUG: ABP 501
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of a Single Dose of SP093 Typhoid Vi Polysaccharide Vaccine in Japanese Subjects
Status: COMPLETED
Conditions: Salmonella Infections|Typhoid Fever|Bacterial Infections
Interventions: BIOLOGICAL: Typhoid Vi polysaccharide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of Glucose Concentrations in People Without Diabetes Mellitus After Standardized Meals and in Daily Life
Status: COMPLETED
Conditions: Subjects Without Diabetes Mellitus|Assessment of Glucose Concentrations
Interventions: DEVICE: Blood glucose monitoring system and continuous interstitial glucose monitoring system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigating the Efficacy of ApplTree on Prospective Memory in Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke (CVA) or TIA|Memory Impairment
Interventions: OTHER: ApplTree smartphone application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bisphosphonates for Prevention of Post-Denosumab Bone Loss
Status: COMPLETED
Conditions: IOP|Osteoporosis
Interventions: DRUG: Alendronate|DRUG: Zoledronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Nitrate in Vegetables on Blood Pressure in Subjects With Prehypertension
Status: COMPLETED
Conditions: Hypertension|Cardiovascular Disease
Interventions: OTHER: High nitrate vegetables|DIETARY_SUPPLEMENT: Low nitrate vegetables + nitrate|OTHER: Low nitrate vegetables
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Safety of Vildagliptin (100mg qd) In Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of TRI476 (Oxcarbazepine) in Children With Inadequately Controlled Partial Onset Seizures
Status: COMPLETED
Conditions: Partial Onset Seizures
Interventions: DRUG: TRI476|DRUG: Placebo to TRI476|DRUG: Benzodiazepines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: L-Cell Activity in Small Intestine as Biliopancreatic Loop in Obese Patients With DM2 Submitted to RYGBP
Status: UNKNOWN
Conditions: Severe Obesity|Type 2 Diabetes Mellitus in Obese
Interventions: OTHER: Analyze basal expression incretin for immunolabeling and mRNA expression glucagon-like secretion peptide-1 (GLP-1) and peptide YY (PYY 3-36) incretins by L cells.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Honghuaruyi Wan for Endometriosis Dysmenorrhea
Status: UNKNOWN
Conditions: Endometriosis|Dysmenorrhea
Interventions: DRUG: Honghuaruyi Wan|DRUG: Placebo of Honghuaruyi Wan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Performance of Flexible Self-adherent Absorbent Dressing Coated With a Soft Silicone Layer After Hip -,Knee- Arthroplasty,Primary Spine Surgery in Comparison to a Standard Wound Dressing
Status: COMPLETED
Conditions: Hip-arthroplasty|Knee-arthroplasty|Spine Surgery
Interventions: DEVICE: Mepilex Border®|DEVICE: Cosmopor steril®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Evaluate the Efficacy and Safety of Three Fixed Doses of Extended-release Paliperidone in Subjects With Bipolar I Disorder
Status: COMPLETED
Conditions: Bipolar Disorder|Mood Disorders
Interventions: DRUG: Paliperidone extended-release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Immediate Endoscopic Necrosectomy vs. Step-up Endoscopic Interventions in Necrotizing Pancreatitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatitis,Acute Necrotizing
Interventions: PROCEDURE: Immediate endoscopic necrosectomy|PROCEDURE: Step-up endoscopic interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Skin Barrier Disruption Due to Daily Use of Cleaning Products and Hand Disinfectants
Status: NOT_YET_RECRUITING
Conditions: Control Condition (PBS)|Household Detergent Exposure|Hand Disinfectant Exposure|Surfactant Exposure|Other Ingredients Exposure
Interventions: OTHER: Cleaning product exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Jaktinib Hydrochloride Tablets in Intermediate-risk and High-risk Myelofibrosis.
Status: COMPLETED
Conditions: Myelofibrosis
Interventions: DRUG: Jaktinib hydrochloride tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Tapered- vs. Cylindrical-shaped Tube Cuffs Pressure Alteration With Nitrous Oxide
Status: COMPLETED
Conditions: Adverse Effect of Other General Anesthetics|Anesthesia Intubation Complication|Inhalation of Nitrous Oxide|Trachea
Interventions: DEVICE: Cylindrical-shape cuff ETT (Group C)|DEVICE: Tapered-shape cuff ETT (Group T)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Dose-Esc/Exp RMC4630 & Cobi in Relapsed/Refractory Solid Tumors & RMC4630& Osi in EGFR+ Locally Adv/Meta NSCLC
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: RMC-4630|DRUG: Cobimetinib|DRUG: Drug: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tirofiban for Reduction of Thromboembolic Events in Endovascular Unruptured Aneurysm Repair
Status: RECRUITING
Conditions: Unruptured Intracranial Aneurysm|Flow Diverter|Stent-assisted Coiling|Thromboembolic Events
Interventions: DRUG: Tirofiban|DRUG: aspirin, clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vibrotactile Coordinated Reset: A Non-invasive Treatment for Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson Disease
Interventions: DEVICE: Active Vibrotactile Coordinated Reset (vCR)|DEVICE: Sham Vibrotactile Coordinated Reset (vCR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Flavors on Nicotine Perception and Self-Administration Via E-cigarettes
Status: COMPLETED
Conditions: Nicotine|E-liquid Flavors
Interventions: DRUG: Nicotine 0 mg/mL|DRUG: Nicotine 6 mg/mL|DRUG: Nicotine 12 mg/mL|DRUG: Nicotine 24 mg/mL|OTHER: 'Menthol' flavor|OTHER: 'Menthol/Mint' flavor|OTHER: 'Green Apple' flavor|OTHER: 'Watermelon' flavor|OTHER: 'Unflavored'
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Feasibility of a Trial of Laparoscopic Hysterectomy Versus Laparoscopic Sub-Total Hysterectomy
Status: UNKNOWN
Conditions: Benign Disease of the Uterus
Interventions: PROCEDURE: Laparoscopic Hysterectomy|PROCEDURE: Laparoscopic Supracervical Hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of DS-1040b in Acute Ischemic Stroke Patients Treated With Thrombectomy
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: DS1040b|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT