pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-028/KEYNOTE-28)
Status: COMPLETED
Conditions: Solid Tumor
Interventions: BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PETRA: PErtuzumab and Trastuzumab Biosimilars Real Life Association for the First Line Treatment of HER2-positive Metastatic Breast Cancer, an Observational Prospective Multicenter Study
Status: UNKNOWN
Conditions: HER-2 Positive Breast Cancer
Interventions: OTHER: Efficacy of the Pertuzumab-Trastuzumab combination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quantitative Mass Transfer of SFP-iron From Dialysate to Blood in CKD-HD Patients
Status: COMPLETED
Conditions: Kidney Failure
Interventions: DRUG: Soluble Ferric Pyrophosphate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Safety, Pharmacokinetics, and Efficacy of ScTIL (Genetically Modified Tumor Infiltrating Lymphocytes) in the Treatment of Gynecological Malignancies
Status: UNKNOWN
Conditions: Cervical Cancer|Ovarian Cancer|Malignant Trophoblastic Tumor
Interventions: DRUG: Toripalimab + ScTIL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SYN-004 for the Prevention of C.Diff in Patients With a LRTI
Status: COMPLETED
Conditions: Clostridium Difficile|Clostridium Infections
Interventions: DRUG: SYN-004|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Varenicline and Bupropion for Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Use Disorder|Alcoholism|Alcohol Dependence
Interventions: DRUG: Varenicline Tartrate 1 mg b.i.d|DRUG: Bupropion Hydrochloride 150 mg b.i.d|OTHER: Placebo for varenicline|OTHER: Placebo for bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study Comparing Two Dose Schedules of Telintra™ in Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Myelodysplastic Syndrome (MDS)
Interventions: DRUG: Ezatiostat Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Impact of Ferric Carboxymaltose Compared With Iron Sucrose in Chinese Subjects on Correcting Iron Deficiency Anaemia
Status: COMPLETED
Conditions: Iron Deficiency Anemia
Interventions: DRUG: Ferric carboxymaltose|DRUG: Iron sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Cognitive Behavioral Therapy for Anxiety and Bipolar I Disorder
Status: COMPLETED
Conditions: Bipolar Disorder|Anxiety Disorders
Interventions: BEHAVIORAL: UP CBT|DRUG: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ⅱ Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells in the Treatment of Venous Leg
Status: RECRUITING
Conditions: Venous Leg Ulcer
Interventions: OTHER: stem cell preparation combined with silver ion dressing|PROCEDURE: silver ion dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Locally Advanced Cancer of the Vulva
Status: COMPLETED
Conditions: Stage III Vulvar Cancer|Stage IVB Vulvar Cancer|Vulvar Squamous Cell Carcinoma
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|DRUG: Cisplatin|PROCEDURE: Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daily Dose Estimation of Jarlsberg Cheese in Healthy Norwegian Elderly Male and Female
Status: COMPLETED
Conditions: Healthy Aging
Interventions: DIETARY_SUPPLEMENT: Jarlsberg cheese
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness: A Pilot RCT
Status: COMPLETED
Conditions: Bacteremia
Interventions: OTHER: 7 days of adequate antibiotic treatment durations|OTHER: 14 days of adequate antibiotic treatment durations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HI-CHART:Feasibility of High-Dose Accelerated Conformal Radiotherapy
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: PROCEDURE: dose escalation (radiotherapy treatment schedule)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Brazilian Fruits Peel on Metabolic Regulation and Appetite in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Control drink|DIETARY_SUPPLEMENT: Brazilian fruit peel flour|DIETARY_SUPPLEMENT: Negative control drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Women Lift Safely! An Intervention Study to Reduce the Risks of Heavy Lifting
Status: COMPLETED
Conditions: Behavior, Health|Behavior, Maternal|Work Related Stress
Interventions: BEHAVIORAL: Information about benefits of the behavior|BEHAVIORAL: Instruction on how to perform a behavior|BEHAVIORAL: Self-efficacy|BEHAVIORAL: Social Support
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Preventing Complications in Cleft Palate Repair With Antibiotics
Status: COMPLETED
Conditions: Cleft Palates
Interventions: DRUG: Unasyn|OTHER: saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Ketamine as an Adjuvant to Opioids for Pain Treatment in Cancer Patients
Status: UNKNOWN
Conditions: Cancer|Pain|Tolerance
Interventions: DRUG: oral ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Pre-Consultation Medication Reconciliation Service in Reducing Unintentional Medication Discrepancies During Transition of Care From Hospital Discharge to Primary Care Setting
Status: COMPLETED
Conditions: Medication Administered in Error|Medication Adherence
Interventions: OTHER: Pre-Consultation Medication Reconciliation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pectoral Nerve Block Versus Paravertebral Block In The Incidence of Chronic Pain After Mastectomy:
Status: NOT_YET_RECRUITING
Conditions: Paravertebral Block|Pectoral Nerve Block|Chronic Pain|Mastectomy; Lymphedema
Interventions: PROCEDURE: thoracic paravertebral block (TPVB)|PROCEDURE: PECS group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab in the Treatment of Scleritis and Non-Infectious Orbital Inflammation
Status: COMPLETED
Conditions: Scleritis|Orbital Disease
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Back Care Pillow in Addition to Physical Therapy in Chronic Non-specific Low Back Pain Treatment
Status: COMPLETED
Conditions: Chronic Nonspecific Low Back Pain
Interventions: DEVICE: Back care pillow|PROCEDURE: standard physical therapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of 2 Interventions to Reduce Fatigue in Patients With Chemotherapy for Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer Metastatic
Interventions: BEHAVIORAL: Hypnosis|BEHAVIORAL: CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fascial Closure Technique After Gynecologic Laparoscopic Surgery and Postoperative Pain
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DEVICE: Traditional Direct Fascial Closure|DEVICE: Fascial Closure Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life, Symptoms and Treatment Satisfaction in Adult Patients With Relapsed and/or Refractory Multiple Myeloma, Receiving Ixazomib (Ninlaro®) in Combination With Lenalidomide and Dexamethasone in a Real World Setting: Pilot Study
Status: UNKNOWN
Conditions: Relapsed and/or Refractory Multiple Myeloma
Interventions: DRUG: ixazomib in combination with lenalidomide and dexamethasone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Dexycu in Treating Intraocular Inflammation
Status: COMPLETED
Conditions: Inflammation|Cataract
Interventions: DRUG: Dexycu|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Radiotherapy Combined With Nedaplatin Contrast and Cisplatin for the Treatment of Locally Advanced Head and Neck Squamous Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Squamous Carcinoma
Interventions: DRUG: Nedaplatin|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention Study on Hypertension Management Combined With Health Promotion at Commune Level
Status: COMPLETED
Conditions: Hypertension|Cardiovascular Risk Factor|Lifestyle
Interventions: OTHER: Commune Hypertension Management
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: First-in-Human Single and Multiple Dose of GLPG1205
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG1205 single ascending doses, oral suspension|DRUG: Placebo single ascending doses, oral suspension|DRUG: GLPG1205, multiple ascending doses, oral suspension|DRUG: Placebo, multiple ascending doses, oral suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Safety and Efficacy of IDP-126 Gel to Epiduo® Forte Gel and Vehicle Gel
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: IDP-126 Gel|DRUG: IDP-126 Vehicle Gel|DRUG: Epiduo® Forte Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Single Doses of Daridorexant on Electrocardiogram Parameters in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Daridorexant|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Ilioinguinal Block in Laparoscopic Inguinal Hernia Repair
Status: WITHDRAWN
Conditions: Post Operative Pain as Estimated by the Sue of the VAS Score
Interventions: DRUG: Marcaine ½%|PROCEDURE: Needle prick
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oral Oxytocin Modulation of Responses to Emotional Stimuli
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Oral Oxytocin|DRUG: Oral Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sorafenib and Temsirolimus in Treating Patients With Metastatic, Recurrent, or Unresectable Melanoma
Status: COMPLETED
Conditions: Melanoma|Recurrent Melanoma|Stage III Melanoma|Stage IV Melanoma
Interventions: DRUG: sorafenib tosylate|DRUG: temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immune Response Study of GSK Biologicals' Influenza Virus Vaccine 1388442A Compared With Fluarix
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Trivalent influenza vaccine GSK 138842A|BIOLOGICAL: Fluarix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Home-based Transcranial Stimulation in the Treatment of Patients With Refractory Chronic Pain
Status: UNKNOWN
Conditions: Chronic Pain
Interventions: DEVICE: Transcranial electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Detecting Activity to Support Healing
Status: COMPLETED
Conditions: Colorectal Cancer|Peritoneal Cancer|Sedentary Lifestyle
Interventions: BEHAVIORAL: Sedentary Behavior|DEVICE: Bluetooth-enabled activity monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability and Pharmacokinetics of Felbinac Trometamol Eye Drops
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Felbinac trometamol eye drop|DRUG: Placebo eye drop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HFNC Versus Conventional Nasal Cannula in Oxygen Performance in Patients Receiving Colonoscopy Under IV Sedation
Status: UNKNOWN
Conditions: Desaturation of Blood
Interventions: DEVICE: High Flow Nasal Cannula|DEVICE: Conventional Nasal Cannula|OTHER: Patient satisfaction questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Registry for Participants With Cirrhosis Who Achieve a Sustained Virologic Response Following Treatment With a Sofosbuvir-Based Regimen Without Interferon for Chronic Hepatitis C Infection
Status: TERMINATED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: Sofosbuvir|DRUG: Ribavirin|DRUG: LDV/SOF|DRUG: SOF/VEL|DRUG: SOF/VEL/VOX|DRUG: Other SOF-Based Regimen|OTHER: Ineligible parent treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Testing a Novel Parenting Intervention for Children With Autism
Status: UNKNOWN
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Elaborative Reminiscence (ER)|BEHAVIORAL: Present Tense Talk (PTT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Dose Escalation and Expansion Study of NB002 in Participants With Advanced or Metastatic Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: NB002
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Human Chorionic Gonadotropin (hCG) and Epoetin Alfa (EPO) in Traumatic Brain Injury: Dosing Tier 1
Status: UNKNOWN
Conditions: Traumatic Brain Injury
Interventions: DRUG: NTx 265
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Protein Source During Ketogenic Weight Loss Intervention
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Obesity; Endocrine
Interventions: DIETARY_SUPPLEMENT: Protein supplement - Plant protein|DIETARY_SUPPLEMENT: Protein supplement - Animal protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Gene Activity in Fat and Muscle in Diabetics and Healthy Controls
Status: COMPLETED
Conditions: Healthy|Type 2 Diabetes|Endotoxemia
Interventions: DRUG: Escherichia Coli Endotoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Advance® 18PTX® Balloon Catheter Study
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Advance® 18PTX® Balloon Catheter|DEVICE: Advance® 18LP Balloon Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of AG-221 (CC-90007) Versus Conventional Care Regimens in Older Subjects With Late Stage Acute Myeloid Leukemia Harboring an Isocitrate Dehydrogenase 2 Mutation
Status: COMPLETED
Conditions: Leukemia, Myeloid|Isocitrate Dehydrogenase
Interventions: DRUG: AG-221|OTHER: BSC|DRUG: Azacitidine|DRUG: Low-dose cytarabine (LDAC)|DRUG: Intermediate-dose cytarabine (IDAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Factors Affecting the Speed of Recovery After ACL Reconstruction
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Injury|ACL Injury|ACL - Anterior Cruciate Ligament Rupture
Interventions: PROCEDURE: Femoral Nerve Block|PROCEDURE: Adductor Nerve Block|OTHER: No Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protective Effects of L-arginine During Reperfusion by Femoropopliteal Bypass for Lower Limb Ischemic Syndrome in Humans
Status: COMPLETED
Conditions: Skeletal Muscle Ischemia|Severe Lower Limb Ischemia|Mitochondrial Dysfunction
Interventions: DRUG: L-arginine (L-arginine Veyron)|DRUG: Nacl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Reduced in Bed Rest After Coronary Arteriography or Coronary Angioplasty
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: OTHER: 2 hours|OTHER: 4 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Bendamustine Hydrochloride and Rituximab (BR) Compared With R-CVP or R-CHOP in the First-Line Treatment of Patients With Advanced Indolent Non-Hodgkin's Lymphoma (NHL) or Mantle Cell Lymphoma (MCL) - Referred to as the BRIGHT Study
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Mantle Cell Lymphoma
Interventions: DRUG: bendamustine|DRUG: rituximab|DRUG: vincristine|DRUG: prednisone|DRUG: cyclophosphamide|DRUG: doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Tolerability Study of NC762 in Subjects With Advanced or Metastatic Solid Tumors
Status: TERMINATED
Conditions: Advanced or Metastatic Solid Tumors|Ovarian Cancer|Non-small Cell Lung Cancer|Breast Cancer
Interventions: DRUG: NC762
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Basophile Activation Testing (BAT) in Hazelnut Allergy (Hazelnut BAT Study)
Status: COMPLETED
Conditions: Food Allergy
Interventions: DIAGNOSTIC_TEST: Food challenge|DIAGNOSTIC_TEST: skin testing|DIAGNOSTIC_TEST: blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sympathetic Nerve Activity Predictors in Patients With Chronic Obstructive Pulmonary Disease
Status: RECRUITING
Conditions: COPD|Sympathetic Nervous System Diseases|Catecholamine; Overproduction
Interventions: DIAGNOSTIC_TEST: Assessments of the sympathetic nerve activity axis|DIAGNOSTIC_TEST: OSA severity|DIAGNOSTIC_TEST: Determination of PH and right HF severity|DIAGNOSTIC_TEST: Comprehensive lung function and inspiratory muscle function testing.|DIAGNOSTIC_TEST: Assessment of systemic inflammation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Performance Study of the FAST-FIX FLEX System for Meniscal Repairs and Meniscal Transplantations
Status: ACTIVE_NOT_RECRUITING
Conditions: Meniscus Tear
Interventions: DEVICE: FAST-FIX FLEX Meniscal Repair System|DEVICE: FAST-FIX FLEX Meniscal Repair System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sublingual Tonometry to Assess Tissue Perfusion in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: COPD|Healthy Subjects
Interventions: DEVICE: sublingual silicon capillary
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Acetyl-Amantadine as a Biomarker in Patients With Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma Multiforme
Interventions: DIAGNOSTIC_TEST: Amantadine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cisplatin, Capecitabine, Gemcitabine and Epirubicin or Docetaxel for Patients With Stage III or IV Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: capecitabine|DRUG: cisplatin|DRUG: docetaxel|DRUG: epirubicin hydrochloride|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect on Androxal Versus Androgel on Morning Testosterone in Men With Secondary Hypogonadism (Low Testosterone)
Status: COMPLETED
Conditions: Secondary Hypogonadism
Interventions: DRUG: Androxal (enclomiphene citrate)|DRUG: Testosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of Udenafil in Adult Subjects With or Without Impaired Hepatic Function
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Udenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Whole Brain Radiotherapy (WBRT) With Sorafenib for Breast Cancer Brain Metastases (BCBM)
Status: COMPLETED
Conditions: Breast Cancer|Brain Metastases
Interventions: RADIATION: Whole Brain Radiotherapy (WBRT)|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A BIOmarker Driven Trial With Nivolumab and Ipilimumab or VEGFR tKi in Naïve Metastatic Kidney Cancer
Status: COMPLETED
Conditions: Clear Cell Metastatic Renal Cell Carcinoma
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|DRUG: Pazopanib|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Application of Autologous Mitochondria Transplantation for Improving Oocyte Quality.
Status: UNKNOWN
Conditions: Repetition Failure
Interventions: PROCEDURE: autologous mitochondria transplantation|COMBINATION_PRODUCT: autologous mitochondria from bone marrow mesenchymal stem cells into oocyte as well as intracytoplasmic sperm injection (ICSI)|DRUG: intracytoplasmic sperm injection (ICSI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics as a Novel Approach to Modulate Gut Hormone Secretion and Risk Factors of Type 2 Diabetes and Complications
Status: UNKNOWN
Conditions: Obesity|Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Lactobacillus reuteri
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A follow-on Safety Study in Subjects With Crohn's Disease Who Have Previously Been Withdrawn From the Double-blind Study CDP870-031 [NCT00152490] or CDP870-032 [NCT00152425] Due to an Exacerbation of Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: Certolizumab Pegol (CDP870)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Diseases
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: nonmyeloablative allogeneic hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iodine Mapping Using Subtraction in Pulmonary Embolism CT Versus Dual-Energy CT
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: DEVICE: Iodine Mapping using Subtraction in Pulmonary Embolism Computed Tomography versus Dual Energy Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Individualized Therapy For Asthma in Toddlers
Status: COMPLETED
Conditions: Asthma|Wheezing
Interventions: DRUG: daily fluticasone propionate|DRUG: Montelukast|DRUG: as-needed fluticasone propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Cognitive Behavioral Therapy for Insomnia to Treat Insomnia Symptoms in Individuals With Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis|Insomnia
Interventions: BEHAVIORAL: Cognitive behavioral therapy for insomnia|BEHAVIORAL: Sleep and lifestyle education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ALIMTA(Pemetrexed)/Cisplatin and ALIMTA(Pemetrexed)/Carboplatin in Extensive Stage Small Cell Lung Cancer.
Status: COMPLETED
Conditions: Lung Neoplasms
Interventions: DRUG: ALIMTA|DRUG: carboplatin|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of Atezolizumab in Locally Advanced or Metastatic Urothelial or Non-Urothelial Carcinoma of the Urinary Tract
Status: COMPLETED
Conditions: Urinary Tract Cancer
Interventions: DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Polyurethane Male Condoms
Status: COMPLETED
Conditions: Contraception|Prevention of Sexually Transmitted Infections
Interventions: DEVICE: Control Latex Condom C, Polyurethane Condom A, Polyurethane Condom B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Pulpotomy Success of Different Methods
Status: COMPLETED
Conditions: Pulpal Bleeding; Staining|Primary Teeth|Pulpotomy
Interventions: DRUG: Ferric Sulfate (Viskostat; Ultradent, Utah, USA)|DRUG: Ankaferd Blood Stopper (Ankaferd Blood Stopper, Ankaferd Ilaç Kozmetik A.S, Istanbul, Turkey)|DEVICE: Er,Cr:YSGG laser (Waterlase MD, Biolase, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dabrafenib and/or Trametinib Rollover Study
Status: RECRUITING
Conditions: Melanoma|Non Small Cell Lung Cancer|Solid Tumor|Rare Cancers|High Grade Glioma
Interventions: DRUG: dabrafenib|DRUG: trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mental Fatigue on Lower Limb Functional Performance Tests and Brain Activity in a Healthy Population
Status: COMPLETED
Conditions: Mental Fatigue|Return to Sport|EEG|Brain Activity|Functional Performance
Interventions: OTHER: Mental Fatigue|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Additional Effects of Therapeutic Exercises Under a Behavioral Umbrella for Chronic Temporomandibular Disorders Treatment
Status: COMPLETED
Conditions: Temporomandibular Joint Dysfunction Syndrome
Interventions: PROCEDURE: Manual Treatment|PROCEDURE: Myofunctional Motor control exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation for Apathy Treatment in Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer's Disease|Apathy
Interventions: DEVICE: Magnetic Stimulator Magstim Rapid 2|DEVICE: Sham Magnetic Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the DASH Diet at Reducing High Blood Pressure
Status: COMPLETED
Conditions: Cardiovascular Diseases|Hypertension|Heart Diseases
Interventions: BEHAVIORAL: Dietary Approaches to Stop Hypertension (DASH)|BEHAVIORAL: Control Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pasireotide for the Treatment of Gastrointestinal Angiodysplasia in Endoscopic Treatment Failure
Status: COMPLETED
Conditions: Angiodysplasia
Interventions: DRUG: Pasireotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Colchicine Therapy on Arrhythmia Recurrence After Acute Pericardial Effusion
Status: COMPLETED
Conditions: Pericardial Effusion
Interventions: DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pemetrexed Plus Cisplatin as First-line Therapy in Patients With Advanced Non-squamous NSCLC
Status: TERMINATED
Conditions: Carcinoma, Non Small Cell Lung
Interventions: DRUG: Pemetrexed/Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Long-Acting Injectable Risperidone in the Treatment of Methamphetamine Dependence
Status: COMPLETED
Conditions: Methamphetamine Dependence
Interventions: DRUG: long-acting injectable risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Chinese Medicine Oral Rinse for Irradiated Oral Mucositis in Head & Neck Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Neoplasms|Oral Mucositis (Ulcerative) Due to Radiation|Chinese Medicine Oral Rinse
Interventions: DRUG: Chinese Medicine Oral Rinse Formula-I (CMORF-I)|OTHER: Standard Care|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MORE in the Management of Lumbosacral Radiculopathy Symptoms: A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Lumbar Radiculopathy
Interventions: OTHER: Mindfulness Oriented Recovery Enhancement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self-Selection and Actual Use Trial of Ibuprofen 600 mg Immediate Release/Extended Caplet
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: Ibuprofen 600 mg Immediate Release/Extended Release Caplet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tissue Flossing, AIS, PNF on Hamstring Among Knee OA Patients
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Tissue Flossing|OTHER: Active Isolated Stretch|OTHER: Proprioceptive Neuromuscular Facilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stress Interventions in STEM and Non-STEM
Status: COMPLETED
Conditions: MBSR-STEM|PMR-STEM|MBSR-NON-STEM|PMR -NON-STEM
Interventions: BEHAVIORAL: Stress Reduction: MBSR|BEHAVIORAL: Stress Reduction : PMR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Placebo-Controlled Study of Saracatinib (AZD0530) in Patients With Recurrent Osteosarcoma Localized to the Lung
Status: TERMINATED
Conditions: Osteosarcoma
Interventions: DRUG: Saracatinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CPAP and Nebivolol in Hypertensive Obstructive Sleep Apnea (OSA) Patients.
Status: UNKNOWN
Conditions: Hypertension|Endothelial Dysfunction|Obstructive Sleep Apnea
Interventions: DRUG: Nebivolol|DEVICE: Continuous positive airway pressure (CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ranibizumab Vs Bevacizumab for Type 1 Retinopathy of Prematurity
Status: UNKNOWN
Conditions: Retinopathy of Prematurity Both Eyes
Interventions: DRUG: Bevacizumab, Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: BMS-247550 in Treating Patients With Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: ixabepilone|DRUG: Fluoropyrimidine|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Knee Osteoarthritis Treatment With Platelet-rich Plasma
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: PRP Protocol A|BIOLOGICAL: PRP Protocol B|DEVICE: Hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study to Confirm the Cardioprotective Effects of MC-1 in Patients Undergoing High-Risk CABG
Status: COMPLETED
Conditions: Coronary Artery Bypass Graft Surgery|Myocardial Ischemia|Reperfusion Injury
Interventions: DRUG: (MC-1) Pyridoxal 5'-phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: NYSCF Scientific Discovery Biobank
Status: RECRUITING
Conditions: ALS|Amyotrophic Lateral Sclerosis|Alzheimer Disease|Alzheimer Disease, Early Onset|Alzheimer Disease, Late Onset|Batten Disease|Corticobasal Degeneration|Dementia|Frontotemporal Dementia|Huntington Disease|Lewy Body Disease|Multiple Sclerosis|Multiple System Atrophy|Parkinson Disease|Parkinson's Disease and Parkinsonism|Progressive Supranuclear Palsy|INAD|Diabetes|Diabetes Mellitus|Diabetes Mellitus, Type 2|Diabetes Mellitus, Type 1|Macular Degeneration|Ovarian Cancer|Cervical Cancer|Uterine Cancer|Vaginal Cancer|Vulvar Cancer|PTSD|Post Traumatic Stress Disorder
Interventions: OTHER: Biological Sample Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial Evaluating the Clinical Applicability, Correlation, and Modeling of Cardiac CT Using 64 Detector Row VCT
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DEVICE: 64 Channel VCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Controlled Study of ONO-8025 (KRP-197) in Patients With Overactive Bladder in Japan
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: ONO-8025 (KRP-197)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Sweat Analysis as Prognosticator After Heart Attack
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DIAGNOSTIC_TEST: Examination and analysis of sweat and blood samples at baseline and at follow up|DIAGNOSTIC_TEST: Examination and analysis of sweat and blood samples at baseline
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Public Health Messages to Address Vaccine Hesitancy
Status: COMPLETED
Conditions: Vaccine Hesitancy
Interventions: BEHAVIORAL: Parent source|BEHAVIORAL: Doctor source|BEHAVIORAL: Deliberative content|BEHAVIORAL: Intuitive content
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Crestal Bone Loss Around Narrow Diameter Implants Versus Standard Diameter Implants With Bone Augmentation in Horizontally Deficient Posterior Mandibular Sites.
Status: RECRUITING
Conditions: Horizontal Atrophy of Edentulous Alveolar Ridge
Interventions: PROCEDURE: Dental implant: NDI|PROCEDURE: Dental implant: SDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Femoropopliteal In Situ Valve Formation With the InterVene System - INFINITE-US
Status: TERMINATED
Conditions: Chronic Venous Insufficiency (CVI)|Deep Vein Reflux
Interventions: DEVICE: BlueLeaf® Endovenous Valve Formation System (BlueLeaf System)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: FOR HEALTH: A Family-oriented Healthy Eating, Activity and Lifestyle Intervention for Overweight Preschool Children
Status: TERMINATED
Conditions: Childhood Obesity
Interventions: BEHAVIORAL: Multidisciplinary, family-centered lifestyle intervention with behavioral counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Investigate the Pharmacokinetics of EPORON® and EPREX® After Subcutaneous Administration in Healthy Male Volunteers
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: EPORON|DRUG: EPREX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of Cognitive Rehabilitation Effectiveness for Mild Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury With Brief Loss of Consciousness|Traumatic Brain Injury With No Loss of Consciousness
Interventions: BEHAVIORAL: Cognitive Rehab|BEHAVIORAL: Brainworks|BEHAVIORAL: Informational Handout/Provider Visits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Training in Goal-directed Attention Regulation for Individuals With Brain Injury
Status: COMPLETED
Conditions: Brain Injury
Interventions: BEHAVIORAL: training in goal-directed attention regulation|BEHAVIORAL: brain health education|BEHAVIORAL: computer-assisted training in goal-directed attention regulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy in Hepatocellular Carcinomas After Hepatectomy With Narrow Margin (<1 cm) and / or Microvascular Invasion
Status: UNKNOWN
Conditions: HepatoCellular Carcinoma
Interventions: RADIATION: Postoperative radiotherapy|DRUG: Postoperative TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Incentive Treatment for Alcohol
Status: RECRUITING
Conditions: Alcohol Use Disorder|Alcohol Drinking|Alcohol Abuse|Alcohol Dependence
Interventions: BEHAVIORAL: Contingency Management|BEHAVIORAL: Computer Based Training for Cognitive Behavioral Therapy for AUD (CBT4CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acamprosate to Reduce Symptoms of Alcohol Withdrawal
Status: COMPLETED
Conditions: Alcohol-Related Disorders|Alcohol Dependence|Alcoholism|Healthy Volunteer
Interventions: PROCEDURE: NMR-spectroscopy|DRUG: Oral acamprosate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: General Anesthesia Exposure and Neurodevelopmental Outcome in Pediatrics
Status: UNKNOWN
Conditions: Anesthesia|Infant Development|Anesthesia; Adverse Effect
Interventions: DIAGNOSTIC_TEST: Eyetracker|DIAGNOSTIC_TEST: Ages & Stages questionnaire|DIAGNOSTIC_TEST: Bayley Scale of Infant Development
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Interval Aerobic Training and Mindfulness Breathing on Hormonal, Metabolic, and Tumor Markers in Postmenopausal
Status: RECRUITING
Conditions: Insulin Resistance
Interventions: OTHER: interval training|OTHER: diet recommendations|OTHER: mindfulness breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia
Status: RECRUITING
Conditions: Myelofibrosis|Moderate Thrombocytopenia
Interventions: DRUG: Selinexor 60 mg|DRUG: Selinexor 40 mg|DRUG: Ruxolitinib|DRUG: Pacritinib|DRUG: Momelotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Single Rinsing With Three Different Types of Mouthwash on VSC Levels in Morning Breath
Status: COMPLETED
Conditions: Halitosis
Interventions: PROCEDURE: 0.05%chlorhexidine mouthwash|PROCEDURE: 0.05% sodium fluoride mouthwash|PROCEDURE: alcohol free essential oils mouthwash|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Clinical Efficacy of Amoxicillin Given Twice or Three Times a Day Among Children With Non-severe Pneumonia
Status: COMPLETED
Conditions: Community-acquired Pneumonia
Interventions: DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Preoperative Antibiotics on Peri-implant Healing
Status: UNKNOWN
Conditions: Dental Implant Failed
Interventions: DRUG: Azithromycin|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of Investigational Treatments in Combination With Standard of Care Immune Checkpoint Inhibitors in Participants With Advanced Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: TAK-580|DRUG: TAK-202|DRUG: vedolizumab|DRUG: nivolumab|DRUG: ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Expanded Cohort for Metastatic Colorectal Cancer (MCRC) Using Bevacizumab + Everolimus
Status: COMPLETED
Conditions: Colorectal Adenocarcinoma
Interventions: DRUG: Bevacizumab|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of Ifosfamide, Etoposide, Cytarabine, and Methotrexate (IVAM) Chemotherapy for Refractory or Relapsed Diffuse Large B Cell Lymphoma
Status: ENROLLING_BY_INVITATION
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Ifosfamide, Etoposide, Cytarabine, and Methotrexate (IVAM) Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT