pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Phase I Study Investigating the Combination of Cladribine, Low Dose Cytarabine and Sorafenib Alternating With Decitabine in Pediatric Relapsed and Refractory Acute Leukemias
Status: NOT_YET_RECRUITING
Conditions: Refractory Acute Leukemia|Relapsed Acute Leukemia
Interventions: DRUG: Cladribine|DRUG: Cytarabine|DRUG: Sorafenib|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Host Iron Status and Iron Supplement Use on Erythrocytic Stage of Plasmodium Falciparum
Status: COMPLETED
Conditions: Iron Deficiency Anemia|Malaria
Interventions: DIETARY_SUPPLEMENT: Iron Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: KD019 and Trastuzumab in Patients With Esophagus, Gastroesophageal Junction and Stomach Cancer
Status: WITHDRAWN
Conditions: Esophageal Cancer|Stomach Cancer
Interventions: DRUG: KD019
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Transversus Abdominis Plane Block: A Prospective Randomized Clinical Trial Using EXPAREL.
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Exparel|PROCEDURE: TAP Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Prehabilitation Exercise Program on Physical Functioning for Patients Undergoing Kidney Transplantation
Status: RECRUITING
Conditions: End Stage Renal Disease
Interventions: BEHAVIORAL: Exercise and Prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase IIb, Open-Label, Dose Ranging Study of 13-Valent Pneumococcal Conjugate Vaccine in Adults 55 Through 74 Years of Age Previously Vaccinated With 23-Valent Pneumococcal Polysaccharide Vaccine
Status: COMPLETED
Conditions: Pneumococcal Infection
Interventions: BIOLOGICAL: Pneumococcal 13-valent Conjugate Vaccine [Diphtheria CRM197 Protein]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: Tele-Rehabilitation in Patients With Temporomandibular Dysfunction
Status: RECRUITING
Conditions: Temporomandibular Disorder|Temporomandibular Joint Disorders|Temporomandibular Joint Dysfunction Syndrome
Interventions: OTHER: manual therapy and therapy by exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Efficacy and Safety of Lixisenatide in Patients With Type 2 Diabetes Insufficiently Controlled With Basal Insulin +/- Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Lixisenatide (AVE0010)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Competitive Accuracy of Radiological Imaging Compared to Liver Biopsy in Patients With Liver Fibrosis
Status: COMPLETED
Conditions: Liver Fibroses|Liver Cirrhosis
Interventions: DIAGNOSTIC_TEST: Liver elastography (2D-SWE)|DIAGNOSTIC_TEST: Liver scintigraphy with 99mTc-mebrofenin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Efficacy and Safety of Lovaza (Omega-3-Acid Ethyl Esters) in Recurrent, Symptomatic Atrial Fibrillation
Status: COMPLETED
Conditions: Fibrillation, Atrial
Interventions: DRUG: omega-3-acid ethyl esters|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pancreatic Enzyme Replacement and Glucose Regulation in Type 1 Diabetes
Status: ENROLLING_BY_INVITATION
Conditions: Type 1 Diabetes
Interventions: DRUG: CREON|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Preliminary Efficacy for LDK378 in Japanese Patients With Genetic Alterations in Anaplastic Lymphoma Kinase (ALK)
Status: COMPLETED
Conditions: Tumors Characterized by Genetic Alterations in Anaplastic Lymphoma Kinase (ALK)
Interventions: DRUG: LDK378
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dietary Oils to Sustain Energy Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Overweight and Obesity
Interventions: OTHER: Soybean Oil Foods|OTHER: Palm Oil Foods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Adefovir and Tenofovir for the Treatment of Lamivudine-Resistant Hepatitis B Virus in People With HIV
Status: COMPLETED
Conditions: HIV Infections|Hepatitis B
Interventions: DRUG: Adefovir dipivoxil|DRUG: Tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Evaluation of Cavir Tab. 0.5mg With Food Effect on Pharmacokinetics and Safety
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Baraclude Tab. 0.5mg, fasting|DRUG: Cavir Tab. 0.5mg, fasting|DRUG: Cavir Tab. 0.5mg, high fatty meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low Level Laser Therapy for Autoimmune Thyroiditis
Status: COMPLETED
Conditions: Autoimmune Thyroiditis
Interventions: PROCEDURE: Low-level laser therapy|PROCEDURE: Non laser ordinary red light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modulation of Remifentanil-induced Postinfusion Hyperalgesia
Status: COMPLETED
Conditions: Hyperalgesia, Secondary
Interventions: OTHER: Placebo|DRUG: Remifentanil|DRUG: Ketorolac and remifentanil|DRUG: Parecoxib and remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimizing a Bio-behavioral Intervention for Sustained Viral Suppression
Status: RECRUITING
Conditions: HIV Viremia
Interventions: BEHAVIORAL: Peer support to promote uptake and persistence of medication assisted treatment (MAT)|BEHAVIORAL: Behavioral Activation Treatment (BAT) to reduce depression|BEHAVIORAL: No Intervention Components
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Pharmacokinetics of Lemborexant (E2006) and Its Metabolites in Subjects With Normal Renal Function or With Severe Renal Impairment
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: Lemborexant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plasma CO2 Removal Due to CRRT and Its Influence on Indirect Calorimetry
Status: COMPLETED
Conditions: Continuous Renal Replacement Therapy|CO2 Removal|Nutrition Poor|Acute Renal Failure
Interventions: DIAGNOSTIC_TEST: blood gas analysis under citrate predilution|DEVICE: filter replacement|DEVICE: IC|DRUG: NaCl predilution|DIAGNOSTIC_TEST: blood gas analysis under NaCl predilution|DRUG: double ultrafiltration|DIAGNOSTIC_TEST: blood gas analysis under citrate predilution and double ultrafiltration rate|DIETARY_SUPPLEMENT: pause and restart nutritional therapy|DIAGNOSTIC_TEST: evolution of vitamin and trace elements
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Retrospective Effectiveness Study of Dalbavancin and Other Standard of Care of the Same Class in Patients With ABSSSI
Status: COMPLETED
Conditions: Acute Bacterial Skin and Skin Structure Infection
Interventions: DRUG: Xydalba|DRUG: vancomycin, teicoplanin or daptomycin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Valacyclovir as Treatment for Genital Herpes Simplex Virus in HIV-Infected Patients
Status: UNKNOWN
Conditions: Herpes Simplex|HIV Infections|Herpes Genitalis
Interventions: DRUG: Valacyclovir hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Single Voiding Cycle and Two and Three Voiding Cycles in Ambulatory Urodynamic Studies
Status: NOT_YET_RECRUITING
Conditions: Urodynamics|Urinary Incontinence|Urogenital Disease, Female|Lower Urinary Tract Symptoms
Interventions: DIAGNOSTIC_TEST: Ambulatory Urodynamic Study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Determine the Safety, Maximum Tolerated Dose, Pharmacokinetics of Sorafenib (BAY43-9006)
Status: COMPLETED
Conditions: Carcinoma
Interventions: DRUG: Sorafenib 100 mg (50-mg tablet)|DRUG: Sorafenib 200 mg (50-mg tablet)|DRUG: Sorafenib 400 mg (50-mg tablet)|DRUG: Sorafenib 400 mg (200-mg tablet)|DRUG: Sorafenib 400 mg (Expansion)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preliminary Study of Piclozotan in Patients With Motor Complications Associated With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: piclozotan|DRUG: 0.9% sodium chloride (normal saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of High-intensity Intermittent Sprinting on Appetite Control on Obese Volunteers
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: resting - control|BEHAVIORAL: Moderate intensity exercise|BEHAVIORAL: High intensity intermittent training|BEHAVIORAL: Short sprint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Strong People Strength Training Study
Status: COMPLETED
Conditions: Heart Diseases|Cardiovascular Diseases|Diabetes|Sedentary Lifestyle|Overweight and Obesity|Depression, Anxiety|Stress|Fatigue
Interventions: BEHAVIORAL: Strong People Strength Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Enteral Nutrition Product in Mild Acute Pancreatitis
Status: UNKNOWN
Conditions: Acute Pancreatitis|Enteral Nutrition
Interventions: DIETARY_SUPPLEMENT: T-Diet plus Atémpero|DIETARY_SUPPLEMENT: AlitraQ (Abbott)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluate The Efficacy and Safety Of Pregabalin In Prevention, Reduction of Oxaliplatin-Induced Painful Neuropathy
Status: COMPLETED
Conditions: Pain|Neuropathic Pain|Polyneuropathy
Interventions: DRUG: Pregabalin, Oxaliplatin|DRUG: Placebo , Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Radiotracer ([18F]FluorThanatrace) by PET/CT for the Imaging of Breast Cancer
Status: SUSPENDED
Conditions: Breast Carcinoma
Interventions: PROCEDURE: Computed Tomography|RADIATION: Fluorine F 18 Fluorthanatrace|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Developing and Evaluating a Meta-cognitive Intervention Amongst Adolescents With Neuro-development Disabilities
Status: COMPLETED
Conditions: Adolescent Behavior
Interventions: OTHER: functional individualized therapy for teenagers with executive deficits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: TEIPP Immunotherapy in Patients With NSCLC
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: TEIPP24 (LRPAP7-30V-SLP vaccine in Montanide ISA-51)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetic Study of SC1011 in Healthy Subjects
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: SC1011|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation and TB
Status: UNKNOWN
Conditions: Tuberculosis|Vitamin D|Immunity
Interventions: DIETARY_SUPPLEMENT: Vitamin D (600 IU)|DIETARY_SUPPLEMENT: Vitamin D (2000 IU)|DIETARY_SUPPLEMENT: Vitamin D (4000 IU)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Expanded Controlled Study of Safety and Efficacy of MCI-186 in Patients With Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: DRUG: MCI-186|DRUG: Placebo of MCI-186
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Rapamycin Versus Vigabatrin in the Prevention of Tuberous Sclerosis Complex Symptoms in Infants
Status: RECRUITING
Conditions: Tuberous Sclerosis Complex
Interventions: DRUG: Vigabatrin|DRUG: Rapamycin|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Vitamin D Supplementation in Type 2 Diabetes
Status: COMPLETED
Conditions: DIABETES MELLITUS
Interventions: DRUG: Vitamin D3|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study to Compare Intravenous and Oral Acetaminophen for the Treatment of Acute Moderate to Severe Pain
Status: TERMINATED
Conditions: Acute Pain, Postoperative
Interventions: DRUG: IV acetaminophen|DRUG: Oral acetaminophen|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Field Cancerization for Reduction in Tumor Burden - A Prospective Study
Status: TERMINATED
Conditions: Extensive Photodamage|Actinic Keratosis|History of Numerous Skin Cancers
Interventions: DEVICE: Ultrapulse Carbon Dioxide Laser|DEVICE: Cellutome epidermal harvesting system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Three-point Transversus Abdominis Plane Block Compared With Continuous Epidural Infusion for Post-laparoscopic Nephrectomy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: TAP Blocks|PROCEDURE: continuous epidural infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized Phase III Study of Intensive Consolidation With High Dose Cytosine Arabinoside in Acute Myelogenous Leukemia (AML-8B)
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: sargramostim|DRUG: amsacrine|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effectiveness of onaBoNT-A vs Oral Tamsulosin in Men With BPH and LUTS
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia|Lower Urinary Track Symptoms
Interventions: DRUG: onaBoNT-A + placebo|DRUG: Tamsulosin + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Self-Distancing for Pediatric Anxiety and OCD
Status: NOT_YET_RECRUITING
Conditions: Anxiety Disorders|Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Self-Distancing (EXSD)|BEHAVIORAL: Classic Exposure (EXC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Genomic Analysis in Tissue Samples From Patients With Recurrent or Stage IV Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Recurrent Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: OTHER: cytology specimen collection procedure|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of KAM2904 Face Cream and KAM3008 Body Lotion Treatment in Children With Atopic Dermatitis (AD)
Status: UNKNOWN
Conditions: Atopic Dermatitis
Interventions: DEVICE: KAM2904 Face Cream|DEVICE: KAM3008 Body Lotion|OTHER: petrolatum-based moisturizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: WP1066 in Children With Refractory and Progressive or Recurrent Malignant Brain Tumors
Status: COMPLETED
Conditions: Brain Tumor|Medulloblastoma|Brain Metastases
Interventions: DRUG: WP1066
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers for the Detection of Heavy Alcohol Use in Patients With and Without Liver Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Abuse|Liver Disease
Interventions: PROCEDURE: Plasma and head hair collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Progesterone (17P, Makena®) for Prolongation of Pregnancy in Women With Preterm Rupture of the Membranes (PROM)
Status: COMPLETED
Conditions: Preterm Delivery
Interventions: DRUG: 17-alpha-hydroxy-progesterone caproate, Makena®|DRUG: Castor Oil (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing Specimen Collection Techniques to Screen for Sexually Transmitted Infections in Pregnant Women: A Pilot Study
Status: TERMINATED
Conditions: Sexually Transmitted Diseases
Interventions: DIAGNOSTIC_TEST: Endocervical swab for detection of STI|DIAGNOSTIC_TEST: Vaginal swab for detection of STI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Inorganic Nitrate and OSA
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DIETARY_SUPPLEMENT: Pre-beetroot juice supplementation|DIETARY_SUPPLEMENT: Post-beetroot juice supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: EA for BPS: An RCT and Study for Central Mechanism
Status: RECRUITING
Conditions: Bladder Pain Syndrome
Interventions: PROCEDURE: electroacupuncture|DRUG: Amitriptyline|PROCEDURE: sham electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medium-chain Triglyceride Oil Massage on Growth in Preterm
Status: COMPLETED
Conditions: Preterm Infants|MCT Oil Massage|Growth
Interventions: OTHER: massage with MCT oil (group 1)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of Prone Position in Patients Under Spontaneous Breathing on Intubation or Non-invasive Ventilation or Death Incidence During COVID-19 Acute Respiratory Distress
Status: COMPLETED
Conditions: COVID19|Oxygen Therapy|Prone Position|Spontaneous Ventilation|Respiratory Distress Syndrome
Interventions: OTHER: prone position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tucatinib, Palbociclib and Letrozole in Metastatic Hormone Receptor Positive and HER2-positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Tucatinib in Combination with Palbociclib and Letrozole|DRUG: Tucatinib in Combination with Palbociclib and Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Anti-oxidants to Reduce Sequela of Mild Traumatic Brain Injury (mTBI) After Blast Exposure
Status: COMPLETED
Conditions: Mild Traumatic Brain Injury
Interventions: DRUG: N-acetyl-cysteine (NAC)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of WR 6026 in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in HIV-Infected Patients
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Sitamaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Cognition and Obstructive Sleep Apnea in Parkinson's Disease, Effect of Positive Airway Pressure Therapy
Status: COMPLETED
Conditions: Parkinson's Disease|Obstructive Sleep Apnea
Interventions: DEVICE: auto-adjusting positive airway pressure|OTHER: Nasal dilator strips
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intubation Techniques on Colonoscopy Quality (SINOCOLO2013)
Status: UNKNOWN
Conditions: Colorectal Adenoma|Colorectal Polyp
Interventions: BEHAVIORAL: Abdominal Compression|DEVICE: Guidance of Magnetic Endoscopic Imaging (MEI) System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fluoxetine on Motor Rehabilitation After Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke|Motor Impairment
Interventions: DRUG: fluoxetine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: P2 Study of Postoperative Interferon/Fluorouracil vs Cisplatin/Fluorouracil for Hepatocellular Carcinoma.
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Interferon Alfa、Fluorouracil|DRUG: Cisplatin、Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of HLX07 in Locally Advanced or Metastatic Cutaneous Squamous Cell Carcinoma (CSCC)
Status: UNKNOWN
Conditions: Cutaneous Squamous Cell Carcinoma
Interventions: DRUG: HLX07
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SWOG-9208 Quality of Life and Health Status in Patients With Stage I or Stage II Hodgkin's Disease
Status: COMPLETED
Conditions: Lymphoma|Psychosocial Effects of Cancer and Its Treatment
Interventions: PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures: an Observational Study
Status: TERMINATED
Conditions: Coronary Disease|Myocardial Infarction|Heart Failure|Arrhythmias, Cardiac|Peripheral Artery Disease|Stroke|Ischemic Attack, Transient|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Pulmonary Disease, Chronic Obstructive|Asthma|Renal Insufficiency|Depressive Disorder|Anxiety Disorders|Schizophrenia|Peripheral Nervous System Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Versus Normal Protein Diet in Polycystic Ovary Syndrome (PCOS)
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DIETARY_SUPPLEMENT: High protein diet|DIETARY_SUPPLEMENT: Normal protein diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Safety, Tolerability and Pharmacokinetics of Mulberry Twig Alkaloids in Human
Status: RECRUITING
Conditions: Overweight and Obesity|Healthy
Interventions: DRUG: Experimental: Mulberry Twig Alkaloids Tablets 126 mg single dose in healthy subjects|DRUG: Mulberry Twig Alkaloids Tablets with single dose in healthy subjects|DRUG: Mulberry Twig Alkaloids Tablets with multiple dose in healthy subjects|DRUG: Mulberry Twig Alkaloids Tablets with multiple dose in overweight or obese subjects
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ⁸⁹Zr-Df-IAB22M2C PET/CT in Patients With Selected Solid Malignancies or Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Positron-Emission Tomography|Immunomodulation|Metastatic Solid Malignancies|Hodgkin Lymphoma
Interventions: DRUG: ⁸⁹Zr-Df-IAB22M2C Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized Crossover Trial to Assess the Tolerability of Gonadotropin Releasing Hormone (GnRH) Analogue Administration
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Triptorelin pamoate|DRUG: Leuprolide acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Curcumin on NFE2L2 Gene Expression, Antioxidant Capacity and Renal Function According to rs35652124 in Diabetic Nephropathy
Status: UNKNOWN
Conditions: Chronic Kidney Diseases|Diabetes Mellitus, Type 2|Polymorphism
Interventions: COMBINATION_PRODUCT: Curcumin/NFE2L2 A>G|COMBINATION_PRODUCT: Placebo/NFE2L2 A>G
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia
Status: TERMINATED
Conditions: Childhood Atypical Teratoid/Rhabdoid Tumor|Childhood Central Nervous System Choriocarcinoma|Childhood Central Nervous System Germinoma|Childhood Central Nervous System Mixed Germ Cell Tumor|Childhood Central Nervous System Teratoma|Childhood Central Nervous System Yolk Sac Tumor|Childhood Choroid Plexus Tumor|Childhood Craniopharyngioma|Childhood Ependymoblastoma|Childhood Grade I Meningioma|Childhood Grade II Meningioma|Childhood Grade III Meningioma|Childhood Infratentorial Ependymoma|Childhood Medulloepithelioma|Childhood Mixed Glioma|Childhood Oligodendroglioma|Childhood Supratentorial Ependymoma|Gonadotroph Adenoma|Pituitary Basophilic Adenoma|Pituitary Chromophobe Adenoma|Pituitary Eosinophilic Adenoma|Prolactin Secreting Adenoma|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Anaplastic Large Cell Lymphoma|Recurrent Childhood Brain Stem Glioma|Recurrent Childhood Central Nervous System Embryonal Tumor|Recurrent Childhood Cerebellar Astrocytoma|Recurrent Childhood Cerebral Astrocytoma|Recurrent Childhood Ependymoma|Recurrent Childhood Grade III Lymphomatoid Granulomatosis|Recurrent Childhood Large Cell Lymphoma|Recurrent Childhood Lymphoblastic Lymphoma|Recurrent Childhood Medulloblastoma|Recurrent Childhood Pineoblastoma|Recurrent Childhood Small Noncleaved Cell Lymphoma|Recurrent Childhood Spinal Cord Neoplasm|Recurrent Childhood Subependymal Giant Cell Astrocytoma|Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor|Recurrent Childhood Visual Pathway and Hypothalamic Glioma|Recurrent Childhood Visual Pathway Glioma|Recurrent Pituitary Tumor|Recurrent/Refractory Childhood Hodgkin Lymphoma|T-cell Childhood Acute Lymphoblastic Leukemia|T-cell Large Granular Lymphocyte Leukemia|TSH Secreting Adenoma|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: gamma-secretase/Notch signalling pathway inhibitor RO4929097|OTHER: diagnostic laboratory biomarker analysis|OTHER: pharmacological study|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Vitamin D With Corticosteroids in Active Crohn's Disease
Status: WITHDRAWN
Conditions: Crohn's Disease
Interventions: DRUG: Colecalciferol D3 (Vigantol Oil)|DRUG: Medium chain triglycerides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Yogurt With Spirulina on Cardiometabolic Risk Markers
Status: COMPLETED
Conditions: Overweight and Obesity|PreDiabetes|Hypertension|Dyslipidemias
Interventions: OTHER: Spirulina yogurt|OTHER: Conventional yogurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Ranging Placebo-Controlled Double-Blind Study to Evaluate the Safety and Efficacy of Tezepelumab in Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DRUG: Tezepelumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Controlled Human Malaria Infection in Semi-Immune Kenyan Adults. (CHMI-SIKA)
Status: UNKNOWN
Conditions: Malaria
Interventions: BIOLOGICAL: Plasmodium falciparum sporozoite (PfSPZ)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pediatric Patient Experience on a Diagnostic Path
Status: UNKNOWN
Conditions: Headache|Urinary Incontinence|Growth Deficiency|Visual Impairment|Psychomotor Retardation, Mild to Severe|Demyelinating Diseases|Brain Tumor
Interventions: OTHER: Information leaflet|OTHER: Educational movie|OTHER: Demonstration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of the ICG Distribution in Breast Tumours or in Axillary Lymph Nodes of Patients After Neoadjuvant Therapy
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Indocyanine Green
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of Somatic Symptom in Chinese Community-Dwelling People
Status: COMPLETED
Conditions: Somatization Disorder
Interventions: DIAGNOSTIC_TEST: Assessment of somatic symptom disorder with SSS-CN|DIAGNOSTIC_TEST: Assessment of depressive symptoms disorder with PHQ-9|DIAGNOSTIC_TEST: Assessment of anxiety disorder with GAD-7
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Exergaming Session Frequency on Work Performance, Cognition, and Mobility in Adults Age 55 to 65
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Exergame 2/week|OTHER: Exergaming 3/week|OTHER: Healthy control / Exergaming 1/week
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study of the Effect of Telaprevir in Combination With Peginterferon Alfa-2b and Ribavirin in Pediatric Subjects Infected With Hepatitis C Virus
Status: TERMINATED
Conditions: Hepatitis C
Interventions: DRUG: Telaprevir|DRUG: Peginterferon alfa-2b|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Modulatory Role of Communicated Treatment Rationale on Treatment Expectation Effects in Depression.
Status: COMPLETED
Conditions: Condition: Major Depressive Disorder (MDD)
Interventions: BEHAVIORAL: Biological illness and treatment rationale|BEHAVIORAL: Psychological illness and treatment rationale|DRUG: Active pharmacological placebo|BEHAVIORAL: Active psychological placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lapatinib Ditosylate and Akt Inhibitor MK2206 in Treating Women With Metastatic Breast Cancer
Status: TERMINATED
Conditions: Estrogen Receptor Negative|Estrogen Receptor Positive|HER2/Neu Positive|Progesterone Receptor Negative|Progesterone Receptor Positive|Recurrent Breast Carcinoma|Stage IV Breast Cancer
Interventions: DRUG: Akt Inhibitor MK2206|OTHER: Laboratory Biomarker Analysis|DRUG: Lapatinib Ditosylate|OTHER: Pharmacogenomic Study|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Oral ZIO-101-C in Advanced Solid Tumors and Lymphomas
Status: UNKNOWN
Conditions: Advanced Solid Tumors|Lymphomas
Interventions: DRUG: ZIO-101-C (Darinaparsin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-target Dietary Supplement Tolerability in an Aging Population (MTDSST)
Status: ENROLLING_BY_INVITATION
Conditions: Aging|Age-related Cognitive Decline
Interventions: DIETARY_SUPPLEMENT: Multi-target Dietary Supplement (MTDS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vibration Therapy on Pain, Functionality and Proprioception in İndividuals With Cervical Disc Herniation
Status: COMPLETED
Conditions: Cervical Disc Herniation|Vibration Therapy|Pain|Functionality|Proprioception
Interventions: DEVICE: a percussion massage gun (Compex Fix 2.0)|OTHER: conventional treatment program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AA4500 for the Treatment of Adhesive Capsulitis of the Shoulder
Status: COMPLETED
Conditions: Adhesive Capsulitis|Frozen Shoulder
Interventions: BIOLOGICAL: AA4500 0.29 mg/1 mL|BIOLOGICAL: AA4500 0.58 mg/2 mL|BIOLOGICAL: AA4500 0.58 mg/1 mL|BIOLOGICAL: AA4500 0.58 mg/0.5 mL|OTHER: Shoulder exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of Patients With Thrombocytopenia Following HSCT
Status: COMPLETED
Conditions: Thrombocytopenia|Hematologic Diseases
Interventions: DRUG: Decitabine|DRUG: rhTPO|OTHER: Conventional Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Communication Strategy in the Prevention of Depressive Symptoms in Patients With Covid-19
Status: COMPLETED
Conditions: Critical Illness|Mechanical Ventilation|Covid19
Interventions: BEHAVIORAL: Intervention. Early and integral communication strategy (EICS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Extracorporeal Shock Wave Therapy for Management of Carpal Tunnel Syndrome
Status: NOT_YET_RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Electroshock Wave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Indinavir Plus Ritonavir Plus Two NRTIs vs. Nelfinavir Plus Two NRTIs in HIV Positive Patients (0639-112)(COMPLETED)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: MK0639, indinavir sulfate / Duration of Treatment: 48 Weeks|DRUG: Comparator: nelfinavir mesylate / Duration of Treatment: 48 Weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peritoneal Closure Versus Non Closure During Open Appendectomy
Status: COMPLETED
Conditions: Acute Appendicitis
Interventions: PROCEDURE: open appendectomy with peritoneal closure|PROCEDURE: open appendectomy without peritoneal closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of The Effects of Sevoflurane, Desflurane and Total Intravenous Anaesthesia on Pulmonary Function Tests
Status: UNKNOWN
Conditions: Pituitary Adenoma
Interventions: DRUG: Sevoflurane|DRUG: Desflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Ketogenic Diet for Treatment-Resistant Depression: Dietary Interventions for MEntal Health Study (DIME)
Status: RECRUITING
Conditions: Treatment Resistant Depression|Depression|Mental Illness|Mental Disorder|Depressive Disorder
Interventions: BEHAVIORAL: Ketogenic Diet|BEHAVIORAL: Phytonutrient Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of ProQuad® in Children 6-24 Month Being Evaluated for Solid Organ Transplant
Status: COMPLETED
Conditions: RENAL INSUFFICIENCY, CHRONIC|LIVER FAILURE, ACUTE|HEART DISEASE
Interventions: BIOLOGICAL: ProQuad
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Does Induction PEG-Intron in Combination With Rebetol Enhance the Sustained Response Rates in Patients With CHC
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Ribavirin, Peg interferon alfa 2b|DRUG: induction therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Antibiotic Pretreatment on the Efficacy of WMT in the Treatment of Chronic Constipation
Status: NOT_YET_RECRUITING
Conditions: Chronic Constipation
Interventions: DRUG: Ornidazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ASCT With Nivolumab in Patients With Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Melphalan|DRUG: Nivolumab|PROCEDURE: Autologous Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Esophageal and Anorectal Manometry Catheters
Status: TERMINATED
Conditions: Achalasia|Nutcracker Esophagus|Scleroderma|Esophageal Spasm|Fecal Incontinence
Interventions: DEVICE: Air filled balloon catheter|DEVICE: Solid state catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BIOTRONIK Conduction System Pacing With the Solia Lead
Status: ACTIVE_NOT_RECRUITING
Conditions: Bradycardia|Atrioventricular Block|Left Bundle-Branch Block|Cardiomyopathies
Interventions: DEVICE: Solia S lead
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Buccal Fat Pad and Subepithelial Connective Tissue Graft
Status: COMPLETED
Conditions: Gingival Recession
Interventions: BIOLOGICAL: free fat graft|BIOLOGICAL: subepithelial graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Induction Therapy for Multiple Myeloma With Carfilzomib, Lenalidomide,Dexamethasone,Panobinostat
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: Panobinostat|DRUG: Carfilzomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of SmartGuard Technology (Predictive System for Stopping Insulin Before Hypoglycemia) in Children With Type 1 Diabetes Treated With Insulin Pump
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Continuous glucose monitoring with the stop insulin pump function
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Symbicort on GR Localisation in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Placebos|DRUG: Formoterol Inhalant Powder|DRUG: Budesonide Powder|DRUG: Budesonide and Formoterol Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Enoxaparin Low Molecular Weight Heparin (LMWH) in Advanced Non Small Cell Lung Cancer: Effect on Survival and Symptom Control in Patients Undergoing First Line Chemotherapy (SYRINGES)
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: cisplatin + docetaxel|DRUG: cisplatin + docetaxel + enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemoprophylactic Activity of M5717 in PfSPZ Challenge Model
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: PfSPZ Challenge|DRUG: Palcebo|DRUG: M5717 30 mg|DRUG: M5717 60 mg|DRUG: M5717 80 mg|DRUG: M5717 100 mg|DRUG: M5717 200 mg|DRUG: Placebo|DRUG: M5717 60 mg|DRUG: M5717 100 mg|DRUG: M5717 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bilateral Prophylactic Mastectomy; Should we Preserve the Pectoral Fascia?
Status: RECRUITING
Conditions: BRCA1/2 Mutation|Bilateral Prophylactic Mastectomy|Seroma|Pectoral Fascia
Interventions: PROCEDURE: Fascia pectoralis preservation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: CSD190202: Study to Assess Elements of Abuse Liability for Two Electronic Nicotine Delivery Systems
Status: COMPLETED
Conditions: Smoking|Tobacco Smoking|Tobacco Use
Interventions: OTHER: Product A|OTHER: Product B|OTHER: Product C|OTHER: Product D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Assessment of the Effect of PAP on Energy and Vitality in Mild OSA Patients: The Merge Study
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Continous Positive Airway Pressure|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine or Hyalase : Which of Them Can Augment Lumbar Epidural Steroid Injection in Failed Back Surgery Patients. A Randomized Clinical Trial
Status: COMPLETED
Conditions: Pain, Chronic
Interventions: DRUG: Hylase versus dexmedtemodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Strategies To Prevent Pneumonia 2 (SToPP2)
Status: COMPLETED
Conditions: Infections, Hospital|Ventilator-Associated Pneumonia|Mechanical Ventilation Complication
Interventions: PROCEDURE: Pre-intubation CHX|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improving Neurodevelopment in Adolescents With Congenital Heart Disease
Status: COMPLETED
Conditions: Congenital Heart Disease|Neurodevelopment|Executive Function|Working Memory Training|Infant Open-heart Surgery
Interventions: BEHAVIORAL: Cogmed Working Memory Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: To Assess the Pharmacokinetics, Safety, and Tolerability of AZD8233 in Participants With Chronic Kidney Disease (CKD), End Stage Renal Disease (ESRD) and Healthy Participants.
Status: TERMINATED
Conditions: End Stage Renal Disease
Interventions: DRUG: AZD8233
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transition From Ticagrelor to Clopidogrel Following Acute Coronary Syndrome: To Bolus or Not?
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT