pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clinical Efficacy of Acetaminophen in Mechanical Ventilation in Children With New Coronary Pneumonia
Status: RECRUITING
Conditions: Acetaminophen,Mechanical Ventilation,Critically Ill Children
Interventions: DEVICE: Paracetamol injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laser Therapy, Pain and Carpometacarpal Joint Osteoarthritis Treatment
Status: COMPLETED
Conditions: Thumb Osteoarthritis|Pain|Physical Disorder
Interventions: OTHER: Laser|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of HPV OncoTect ™ for the Etiological Diagnosis of HPV-induced Oropharyngeal Cancers
Status: UNKNOWN
Conditions: Oropharyngeal Cancer
Interventions: DIAGNOSTIC_TEST: HPV OncoTect™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Elderly Falls Prevention With sLiFE Program in Primary Care
Status: RECRUITING
Conditions: Accidental Falls|Frailty|Elderly|Activities, Motor
Interventions: BEHAVIORAL: Intervention Group|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Effects of Food and Morning Versus Evening on Single and Multiple Doses of ONO-5334 in Healthy Post Menopausal Women
Status: COMPLETED
Conditions: Healthy Post Menopausal Women
Interventions: DRUG: ONO-5334|DRUG: ONO-5334
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Imatinib Mesylate in Treating Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Male Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: imatinib mesylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RAD 1601: EDGE Radiosurgery for Intractable Essential Tremor and Tremor-Dominant Parkinson's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Essential Tremor|Parkinson Disease
Interventions: DEVICE: Unframed Virtual Cone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Components Changes by Using of Ringer's Lactated as Detergent In Autologous Blood Cell Transfusion
Status: WITHDRAWN
Conditions: Placenta Accreta Spectrum
Interventions: OTHER: Ringer's Lactated
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Rapid Molecular Diagnostic Method on Antibiotics Exposure Duration in ICU Patients With Postoperative Peritonitis
Status: TERMINATED
Conditions: Postoperative Peritonitis
Interventions: OTHER: rapid molecular diagnosis|OTHER: conventional method analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Cultural Adaptation of the Caregiver TLC Psychoeducational Program to Support Latino Caregivers (CUIDANDO JUNTOS)
Status: RECRUITING
Conditions: Caregivers of People With Dementia
Interventions: BEHAVIORAL: Cuidando juntos
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Patient Preference of Apalutamide Versus Enzalutamide in Patients With Recurrent or Metastatic Hormone-Sensitive Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Apalutamide|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The PASTEC Study: Endoscopic Stenting Versus Surgery for the Treatment of Bile Duct Stricture in Chronic Pancreatitis
Status: TERMINATED
Conditions: Chronic Pancreatitis
Interventions: DEVICE: Endoscopic Biliary Stenting|PROCEDURE: Surgical treatment Bilio-enteric anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Properties of Vortioxetine in Healthy Young Chinese Men and Women
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Vortioxetine 10 mg single dose|DRUG: Vortioxetine 20 mg single dose|DRUG: Vortioxetine 10 mg multiple dose|DRUG: Vortioxetine 20 mg multiple dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MANAGE-VT Registry - MANAGEment of Ventricular Tachycardia Outcomes Registry
Status: RECRUITING
Conditions: Ventricular Tachycardia
Interventions: PROCEDURE: Ventricular Tachycardia Ablation|DEVICE: ICD Implant|DRUG: Antiarrhythmic drug|DIAGNOSTIC_TEST: EKG|DIAGNOSTIC_TEST: Cardioversion|DIAGNOSTIC_TEST: Echocardiogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oxytocin and Tibolone Adjuncts in Treatment Resistant Depression - A Pilot Study
Status: UNKNOWN
Conditions: Depression|Major Depressive Disorder
Interventions: DRUG: Oxytocin|DRUG: Oxytocin and Tibolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Anti-GPRC5D CAR-T Cells Therapy in the Treatment of r/r MM
Status: RECRUITING
Conditions: Multiple Myeloma in Relapse|Multiple Myeloma, Refractory
Interventions: BIOLOGICAL: Anti-GPRC5D CAR-T cells infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Evaluation of ADXS11-001, Mitomycin, 5-fluorouracil (5-FU) and IMRT for Anal Cancer
Status: TERMINATED
Conditions: Anal Cancer
Interventions: BIOLOGICAL: Treatment|DRUG: 5FU|DRUG: Mitomycin|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of aSpirin Versus CilOstazol for Inhibition of Antiplatelet aggRegaTion in Type 2 DM Patients
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Cilostazol|DRUG: Acetylsalicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in Cutaneous Stage L-lll Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: GM-CSF|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Regeneration of Tissue (ART) for Wound Healing
Status: ACTIVE_NOT_RECRUITING
Conditions: Wound of Skin
Interventions: DEVICE: Autologous Regeneration of Tissue (ART) device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamics and Pharmacokinetics of Empagliflozin and Torasemide in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: BI 10773|DRUG: hydrochlorothiazide|DRUG: torasemide|DRUG: BI 10773|DRUG: torasemide|DRUG: BI 10773|DRUG: hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, PK, and Analgesic Effect of INL-001 in Children Following Open Inguinal Hernia Repair
Status: UNKNOWN
Conditions: Inguinal Hernia|Postoperative Pain
Interventions: DRUG: Bupivacaine HCl collagen-matrix implant|DRUG: Bupivacaine HCl infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SLNB After Nipple Sparing Mastectomy
Status: UNKNOWN
Conditions: Sentinel Lymph Node Biopsy|Mastectomy, Subcutaneous
Interventions: DIAGNOSTIC_TEST: Senti-Scint (99mTc- pertechnetate combined with human albumin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beta-glucan and Fatigue in HSCT Survivors
Status: TERMINATED
Conditions: Autologous Haemopoietic Stem Cell Transplant
Interventions: DIETARY_SUPPLEMENT: Beta-glucan|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Tooth Angulation, Alveolar and Basal Bone Anatomical Characteristics on Soft and Hard Tissue Alterations Around Immediate Implants With Customized Healing Abutment
Status: NOT_YET_RECRUITING
Conditions: Immediate Implant|Esthetic Zone|Customized Healing Abutment|Tissue Collapse|Tissue Dimensional Changes
Interventions: PROCEDURE: immediate implant placement with customized healing abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serum Cytokine Levels in Patients With Lumbal Disc Herniation and Effectiveness of Exercise
Status: ACTIVE_NOT_RECRUITING
Conditions: Low Back Pain
Interventions: OTHER: Lumbal stabilization excercises|OTHER: Conventional exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N-Acetylcysteine in Adjunct to DBT for the Treatment of Self-Injurious Behavior in BPD
Status: TERMINATED
Conditions: Borderline Personality Disorder|Self-Injurious Behavior
Interventions: DRUG: N-Acetylcysteine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VFORM: Prospective, Open Label, Study to Evaluate VOLIFT With Lidocaine Treatment for FORehead Contouring and Marionette Lines
Status: COMPLETED
Conditions: Marionette Lines Forehead Contouring
Interventions: DEVICE: Juvéderm® VOLIFT™ with Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Trial of Multiple Oral Doses of OPC-167832 for Uncomplicated Pulmonary Tuberculosis
Status: COMPLETED
Conditions: Pulmonary TB
Interventions: DRUG: 10 mg OPC-167832|DRUG: 30 mg OPC-167832|DRUG: 90 mg OPC-167832|DRUG: 3 mg OPC-167832|DRUG: RHEZ|DRUG: 30 mg OPC-167832 + 300 mg delamanid|DRUG: 30 mg OPC-167832 + 400 mg BDQ|DRUG: 30 mg OPC-167832 + 300 mg delamanid + 400 mg BDQ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Levofloxacin and Prulifloxacin, in Internal Medicine Patients With Acute Exacerbation of COPD
Status: COMPLETED
Conditions: COPD Exacerbation
Interventions: DRUG: Levofloxacin 1 tablet 500 mg once a day|DRUG: Prulifloxacin 1 tablet 600 mg once a day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TIPS Combined With Variceal Embolization for the Prevention of Variceal Rebleeding in Patients With Cirrhosis
Status: COMPLETED
Conditions: Liver Cirrhosis
Interventions: PROCEDURE: TIPS|PROCEDURE: Variceal Embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Does Verapamil Given Orally Prevent Radial Artery Spasm During Transradial Coronary Angiography
Status: RECRUITING
Conditions: Radial Artery Spasm
Interventions: DRUG: Verapamil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Single-Shot Dexmedetomidine Versus Placebo in Preventing Pediatric Emergence Delirium in Strabismus Surgery
Status: COMPLETED
Conditions: Strabismus|Delirium on Emergence|Pediatric Disorders
Interventions: DRUG: Dexmedetomidine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Efficacy, Safety and Tolerability of Once-daily (q.d.) QVA149 in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: indacaterol and glycopyrronium (QVA149)|DRUG: glycopyrronium (NVA237)|DRUG: indacaterol (QAB149)|DRUG: tiotropium|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MODERATE CONTINUOUS TRAINING VERSUS HIIT IN CANCER STADIUM II.
Status: COMPLETED
Conditions: Cancer|Fatigue|Sarcopenia
Interventions: OTHER: Group continuous training at moderate intensity|OTHER: Group high Intensity Interval Training|OTHER: Group control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Resource Information Program for Parents on Lifestyle and Education
Status: COMPLETED
Conditions: Pediatric Obesity
Interventions: BEHAVIORAL: Eat It|BEHAVIORAL: Move It|BEHAVIORAL: eHealth Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of Curcumin in Preventing Postoperative Adhesion of Bilateral Vocal Cords
Status: RECRUITING
Conditions: Glottic Web of Larynx|Laryngeal Stenosis|Glottic Carcinoma|Laryngeal Leucoplakia|Laryngeal Polyp|Laryngeal Papilloma
Interventions: DRUG: Curcumin|DRUG: Mitomycin-C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Microsampling Approach for Monitoring of Kinase Inhibitor Targeted Therapies
Status: RECRUITING
Conditions: Blood Concentrations of Nine Anti-cancer Drugs : Axitinib, Olaparib, regorafénib, Cabozantinib, Niraparib, Talazoparib, Palbociclib, Abemaciclib, Tucatinib
Interventions: OTHER: Measurement of drug concentrations
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunogenicity and Safety of Live Attenuated Influenza Vaccine (Flumist) Administered by Nasal and Sublingual Route
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Influenza vaccine|BIOLOGICAL: Influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Subjects With Open-angle Glaucoma, Pseudoexfoliative Glaucoma, or Ocular Hypertension Naïve to Medical and Surgical Therapy, Treated With Two Trabecular Micro-bypass Stents (iStent)or Travoprost
Status: COMPLETED
Conditions: Open-angle Glaucoma
Interventions: DEVICE: iStent|DRUG: Travoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Father-involvement Telephone Support Intervention on Breastfeeding: RCT
Status: RECRUITING
Conditions: Breast Feeding, Exclusive|Parents
Interventions: BEHAVIORAL: Breastfeeding telephone support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fecal Microbiota Therapy Vs 5-aminosalicylates for Induction of Remission in Newly Diagnosed Mild-moderately Active UC
Status: UNKNOWN
Conditions: Ulcerative Colitis Chronic Mild|Ulcerative Colitis Chronic Moderate
Interventions: BIOLOGICAL: Fecal Microbiota Transplantation|DRUG: Mesalamine Granules|OTHER: Placebo infusion|OTHER: Placebo granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study for Evaluating the Safety of Excessive Consumption of a Plant Sterol-enriched Yoghurt Drink
Status: COMPLETED
Conditions: Healthy|Mild Hypercholesterolemia
Interventions: OTHER: 1- plain low-fat dairy fermented product (drinkable) enriched with plant sterols-esters (1,6g /day equivalent as free sterols).|OTHER: 2- plain low-fat dairy fermented product (drinkable) without plant sterols-esters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: The Intrathecal Morphine for Nephrectomy
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: The intrathecal morphine injection|DRUG: The intravenous patient-controlled analgesia|DRUG: Demerol on demand
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AdvantAGE: Implementation and Evaluation of an Interprofessional Tranistional Care Model for Frail Older Adults
Status: RECRUITING
Conditions: Transitional Care|Multimorbidity|Geriatric Care
Interventions: OTHER: Transitional care model
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of E2086 in Healthy Adult Participants
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: E2086|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.
Status: NOT_YET_RECRUITING
Conditions: Gastrointestinal Cancer|Colon Cancer|Rectal Cancer|Anal Cancer|Esophageal Cancer|Stomach Cancer|Appendix Cancer|Pancreas Cancer|Liver Cancer|Neuroendocrine Tumors
Interventions: OTHER: EQUITY GI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Care Improving Cognition for ADolescents on the Autism Spectrum
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: OTHER: CICADAS and then PEERS|OTHER: PEERS + CICADAS and then no-contact|OTHER: PEERS + Active Comparator and then no-contact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EARLY 3-months Aggrenox Treatment Started Within 24 Hrs of Ischemic Stroke Onset vs. After One Week 100 mg ASA
Status: COMPLETED
Conditions: Cerebrovascular Accident
Interventions: DRUG: Aggrenox bid (ASA 25mg/Dipyridamole ER 200mg)|DRUG: ASA 100 mg qd
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Eluting Balloon for SFA In-stent Restenosis
Status: UNKNOWN
Conditions: In-stent Arterial Restenosis
Interventions: DEVICE: PTA with drug eluting balloon with paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Triple Combination Antiviral Coronavirus Therapy (TriACT) for COVID-19
Status: TERMINATED
Conditions: SARS-CoV Infection|Covid19
Interventions: DRUG: Nitazoxanide|DRUG: Placebo Nitazoxanide|DRUG: Ribavirin|DRUG: Placebo Ribavirin|DRUG: Hydroxychloroquine|DRUG: Placebo Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilates Exercises on Postpartum Fatigue, Maternal Functioning and Quality of Life
Status: COMPLETED
Conditions: Maternal Fatigue
Interventions: OTHER: Pilates excercises, streching and breathing|OTHER: stretching and breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antenatal Testing in Obese Woman, is it Really Necessary?
Status: UNKNOWN
Conditions: Obesity in Pregnancy
Interventions: DEVICE: External fetal monitor for Nonstress test|DEVICE: Ultrasonography for Biophysical profile
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Femoral Versus Jugular Routes for Temporary Hemodialysis in Seriously Ill Patients
Status: COMPLETED
Conditions: Kidney Failure, Acute|Critical Illness
Interventions: PROCEDURE: Femoral route for hemodialysis|PROCEDURE: Jugular route for hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Glucose Optimisation With Angiotensin II Antagonist Losartan (GOAAL)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Amlodipine 10 mg or Losartan 100 mg + Amlodipine 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose:
Clinical trial: Effects on Quality of Life With Zinc Supplementation in Patients With Gastrointestinal Cancer
Status: COMPLETED
Conditions: Gastric Carcinoma|Liver and Intrahepatic Bile Duct Carcinoma|Unresectable Esophageal Carcinoma|Unresectable Pancreatic Carcinoma
Interventions: DIETARY_SUPPLEMENT: Zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Testing Copanlisib as Potentially Targeting Treatment in Cancers With PTEN Loss (MATCH - Subprotocol Z1G)
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Solid Neoplasm
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Copanlisib|PROCEDURE: Radiologic Examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CBT Plus SMC Compared to SMC for Persistent Physical Symptoms in Secondary Care (PRINCE)
Status: COMPLETED
Conditions: Persistent Physical Symptoms (PPS)
Interventions: BEHAVIORAL: Cognitive behavioural therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-Intensity Interval Training(HIIT) on Cardio-metabolic Risk in School-age Children
Status: RECRUITING
Conditions: Cardiovascular Syndrome, Metabolic
Interventions: BEHAVIORAL: HIIT intervention|BEHAVIORAL: General health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Postoperative Analgesia in Laparoscopic Surgery
Status: COMPLETED
Conditions: Surgery
Interventions: OTHER: Auricular Acupuncture|OTHER: Sham Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Novel Approaches for Minimizing Drug-Induced QT Interval Lengthening
Status: RECRUITING
Conditions: Long QT Syndrome|Abnormalities, Drug-Induced
Interventions: DRUG: Progesterone|DRUG: Ibutilide|DRUG: Testosterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Lugol's Solution in Graves' Disease and Toxic Nodular Goiter
Status: RECRUITING
Conditions: Hyperthyroidism
Interventions: DRUG: Iodine-Potassium Iodide 5%-10% Oral and Topical Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perineal Massage and Warm Compresses - RCT for Reduce Perineal Trauma During Labor
Status: COMPLETED
Conditions: Perineal Tear Resulting From Childbirth
Interventions: PROCEDURE: Perineal Massage and Warm Compresses (PeMWaC)|PROCEDURE: Control Group (Hands-on)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Caffeine to Alleviate Dyspnea Related to Ticagrelor
Status: TERMINATED
Conditions: Dyspnea
Interventions: DRUG: Caffeine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of the Vaginal Laser With a Moisturizing and Repairing Niosomal Gel in the Treatment of Genitourinary Syndrome in Oncology Patients
Status: RECRUITING
Conditions: Genitourinary Syndrome of Menopause
Interventions: DEVICE: CO2 laser
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Personalized Repetitive Transcranial Magnetic Stimulation (rTMS) in Cognitive Fluctuations of Dementia With Lewy Bodies (DLB): Proof of Concept
Status: RECRUITING
Conditions: Dementia With Lewy Bodies Diagnosis|Significant Cognitive Fluctuations in DLB
Interventions: DEVICE: rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Daratumumab (HuMax®-CD38) Safety Study in Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Part 1: Daratumumab|DRUG: Part 2: Daratumumab|OTHER: Methylprednisolone|OTHER: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Mesenteric Ischemia Breath Testing
Status: COMPLETED
Conditions: Chronic Mesenteric Ischemia
Interventions: DRUG: Sodium butyrate, 1-13C, 99%, Cambridge Isotope Laboratories, Inc.USA|DRUG: U-13C6, 99%; Cambridge Isotope Laboratories, Inc.USA|DIAGNOSTIC_TEST: Breath test|DIAGNOSTIC_TEST: Exercise + breath test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Precision Probiotic Supplementation in Individuals With Mild Cognitive Impairment
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: Precision probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Heparin and Protamine Titration in Cardiac Surgery Under Minimal Invasive Extracorporeal Circulation
Status: COMPLETED
Conditions: Cardiopulmonary Bypass
Interventions: DEVICE: Hemostasis Management System Plus|DEVICE: Activated Coagulation Timer System Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of High-intensity Laser Therapy on Patients With Myogenic Temporomandibular Joint Dysfunction
Status: NOT_YET_RECRUITING
Conditions: Temporomandibular Joint Dysfunction Syndrome
Interventions: DEVICE: High-intensity laser therapy (HILT)|DEVICE: placebo high-intensity laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics (PK) of E7090 (Herein Referred to as Tasurgratinib) and Its Metabolite in Participants With Mild and Moderate Hepatic Impairment Compared to Healthy Participants
Status: RECRUITING
Conditions: Hepatic Impairment
Interventions: DRUG: Tasurgratinib|DRUG: Tasurgratinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of UX053 in Patients With Glycogen Storage Disease Type III (GSD III)
Status: TERMINATED
Conditions: Glycogen Storage Disease Type III
Interventions: BIOLOGICAL: UX053|OTHER: Placebo|DRUG: Antipyretic|DRUG: H2 Blocker|DRUG: H1 Blocker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cryoballoon Pulmonary Venous Isolation in Patients Referred for Typical Atrial Flutter Ablation
Status: COMPLETED
Conditions: Atrial Flutter|Atrial Fibrillation
Interventions: PROCEDURE: Atrial flutter ablation|PROCEDURE: Atrial flutter ablation and pulmonary vein isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Proof of Concept Study for the DNA Repair Driven by the Mesenchymal Stem Cells in Critical COVID-19 Patients
Status: COMPLETED
Conditions: COVID-19 Pneumonia
Interventions: BIOLOGICAL: Mesenchymal Stem Cells Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PALbociclib Rechallenge in horMone Receptor-posItive/HER2- Negative Advanced Breast Cancer (PALMIRA)
Status: COMPLETED
Conditions: Breast Cancer|Advanced Breast Cancer|Hormone Receptor Positive Tumor|Human Epidermal Growth Factor 2 Negative Carcinoma of Breast
Interventions: DRUG: Palbociclib|DRUG: Endocrine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of E2022 Tape Formulation (Overlay-integrated E2022 18 mg Tape Formulation) for Different Application Sites and Intervals in Japanese Healthy Elderly Males
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: E2022
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Moderate Whole Body Hyperthermia for Patients Undergoing Re-irradiation for Head and Neck Cancer -Influence on the Tumor Microenvironment
Status: COMPLETED
Conditions: Head and Neck Neoplasms|Recurrence Tumor
Interventions: DEVICE: Moderate whole body hyperthermia using water-filtered IR-A-radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preterm Newborn Mothers' Anxiety and Self-Efficacy
Status: COMPLETED
Conditions: Nursing Care|Mother-Infant Interaction|Education
Interventions: OTHER: Group receiving QR code supported training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Monitoring HER2+ Breast Cancer Neoadjuvant Treatment With Advanced PET/MRI
Status: RECRUITING
Conditions: HER2-positive Breast Cancer
Interventions: DRUG: [18F]FMISO PET/MRI imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Applying Mobile Healthcare Education to Improve Cutaneous Self-care Capability
Status: RECRUITING
Conditions: EGFR Gene Mutation|Drug-Related Side Effects and Adverse Reactions|Cancer, Treatment-Related|Cancer
Interventions: BEHAVIORAL: Mobile healthcare education game|BEHAVIORAL: Mobile healthcare education application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Phase II Study of the Combination of Blinatumomab and Asciminib in Patients With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: Philadelphia Chromosome-Positive|Acute Lymphoblastic Leukemia
Interventions: DRUG: Blinatumomab|DRUG: Asciminib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Folfirinox Followed by Capecitabine and Limited Field Radiation for Localized Pancreatic Head Adenocarcinoma
Status: TERMINATED
Conditions: Adenocarcinoma of Head of Pancreas
Interventions: DRUG: Neo-adjuvant Chemotherapy|RADIATION: Chemoradiation|PROCEDURE: Surgical Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-Up Study of Safety of Pneumostem® in Premature Infants With Intraventricular Hemorrhage
Status: UNKNOWN
Conditions: Intracranial Hemorrhages|Mesenchymal Stem Cells|Newborn Infant
Interventions: OTHER: observation without intervention in this follow up study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Steroids In caRdiac Surgery Trial (SIRS Trial)
Status: UNKNOWN
Conditions: Cardiac Surgical Procedures|Cardiopulmonary Bypass|Systemic Inflammatory Response Syndrome
Interventions: DRUG: Methylprednisolone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sodium Zirconium Cyclosilicate Lowers Hyperkalemia After Parathyroidectomy
Status: COMPLETED
Conditions: Sodium Zirconium Cyclosilicate|Hyperkalemia|Hyperparathyroidism, Secondary
Interventions: DRUG: Sodium zirconium cyclosilicate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Isotonic and Hypertonic Saline Infusion on Renal Biomarkers in Healthy Young Subjects
Status: COMPLETED
Conditions: Nephropathy
Interventions: OTHER: isotonic saline 0,9 mg/ml|OTHER: hypertonic saline 2,9 mg/ml|OTHER: glucose 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Red Blood Cell (RBC) Survival Following Transfusion in Infants
Status: COMPLETED
Conditions: Neonatal Anemia
Interventions: BIOLOGICAL: Transfused Biotin RBCs - Adults Phase I|BIOLOGICAL: Transfused Biotin RBCs - Infants Phase II|BIOLOGICAL: Transfused Biotin RBCs - Infants Phase III
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomised Trial Investigating the Additional Benefit of Hydroxychloroquine(HCQ)to Short Course Radiotherapy (SCRT) in Patients Aged 70 Years and Older With High Grade Gliomas (HGG)
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: Hydroxychloroquine|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Cut-Off Continuous Veno-venous Hemodialysis (CVVHD) in Patients Treated for Acute Renal Failure After Systemic Inflammatory Response Syndrome (SIRS)/Septic Shock
Status: TERMINATED
Conditions: Systemic Inflammatory Response Syndrome|Kidney Failure, Acute
Interventions: DEVICE: continuous venovenous hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Healthy Volunteers Study of the Effects of Olanzapine and Ziprasidone
Status: COMPLETED
Conditions: Hyperglycemia|Hyperlipidemia
Interventions: DRUG: Olanzapine|DRUG: Ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: TReatment of Irritable Bowel Syndrome With Diarrhoea Using Titrated ONdansetron Trial
Status: COMPLETED
Conditions: IBS - Irritable Bowel Syndrome
Interventions: DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Strength and Aerobic Training Against Hot Flushes in Postmenopausal Women
Status: RECRUITING
Conditions: Postmenopausal Symptoms|Hot Flashes
Interventions: OTHER: Strength training|OTHER: High-intensity aerobic training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Expression and the Activity of Rac1 Protein in the Airway Smooth Muscle of Asthmatic Patient
Status: COMPLETED
Conditions: Asthma
Interventions: PROCEDURE: Bronchial endoscopy|PROCEDURE: Bronchial biopsies|PROCEDURE: Bronchial alveolar enema
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: CDI Synbiotic Study
Status: UNKNOWN
Conditions: Clostridium Difficile Infection
Interventions: DIETARY_SUPPLEMENT: Synbiotic mixture|OTHER: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Bezafibrate on Muscle Metabolism in Patients With Fatty Acid Oxidation Defects
Status: COMPLETED
Conditions: Carnitine Palmitoyltransferase II Deficiency|Very Long Chain Acyl Coa Dehydrogenase Deficiency
Interventions: DRUG: Bezafibrate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety and Efficacy of Tri-wire Balloon for Treatment of Dysfunctional AV Fistula
Status: UNKNOWN
Conditions: Arteriovenous Fistula
Interventions: COMBINATION_PRODUCT: Combination Product: Tri-wire Peripheral Balloon Dilatation Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of Chest Ultrasound Observation on Extubation Failure
Status: RECRUITING
Conditions: Pulmonary Ultrasound|Weaning Failure|Ultrasound|Lung Edema|Extubation Failure
Interventions: OTHER: Pulmonary Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Orsiro Drug Eluting Stent System
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Percutaneous Coronary Intervention (Abbott Laboratories - Xience Prime DES)|DEVICE: Percutaneous Coronary Intervention (Orsiro DES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Salt and TH-17 in Healthy Human Subjects
Status: TERMINATED
Conditions: Th17 Helper Immune Cells|Autoimmunity|Salt Intake|Sodium Chloride
Interventions: DIETARY_SUPPLEMENT: Low salt diet|DIETARY_SUPPLEMENT: Low salt diet + IV normal saline|DIETARY_SUPPLEMENT: Liberal salt diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Different Types of Exercise on Insulin Resistance and Visceral Adipose Tissue in Community Residents.
Status: COMPLETED
Conditions: Exercise, Insulin Resistance, Visceral Adipose Tissue
Interventions: BEHAVIORAL: exercise|BEHAVIORAL: No exercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lifestyle, Exercise, and Nutrition Study Early After Diagnosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Neoplasms
Interventions: BEHAVIORAL: Dietary/Physical Activity intervention|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Immunization With 4C-MenB in Preventing Experimental Urethral Infection With Neisseria Gonorrhoeae
Status: RECRUITING
Conditions: Gonorrhea Male
Interventions: DRUG: Cefixime|DRUG: Ceftriaxone|DRUG: Ciprofloxacin|BIOLOGICAL: Neisseria gonorrhoeae strain FA1090|BIOLOGICAL: Meningococcal Group B Vaccine|BIOLOGICAL: Influenza Vaccine|BIOLOGICAL: Tetanus-diptheria Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability and Immunogenicity Study of 2-dose Heterologous Regimens for Ebola Vaccines Ad26.ZEBOV/MVA-BN-Filo
Status: COMPLETED
Conditions: Hemorrhagic Fever, Ebola
Interventions: BIOLOGICAL: Ad26.ZEBOV|BIOLOGICAL: MVA-BN-Filo|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Traditional Chinese Medicine in the Treatment of Patients With Hyperuricemia.
Status: COMPLETED
Conditions: Hyperuricemia
Interventions: DRUG: Wu Ling San|DRUG: Yin-Chen Wu Ling San|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Basic and Balance: Logan Basic Technique on Bilateral Weight Balance
Status: COMPLETED
Conditions: Pelvic Adjusting (LBT)
Interventions: PROCEDURE: Logan Basic Apex Contact|PROCEDURE: Sham Logan Basic apex contact
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindful Self Compassion for Combat Deployed Veterans With Moral Injury and Co-occurring PTSD-SUD
Status: COMPLETED
Conditions: Substance Use Disorder|Post-traumatic Stress Disorder|Moral Injury
Interventions: BEHAVIORAL: Mindful Self-Compassion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Benralizumab in People With Skin Side Effects Caused by Cancer Therapies
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor|Solid Carcinoma|Solid Tumor, Adult|Hematologic Malignancy
Interventions: DRUG: Benralizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk of Reactivation of Occult Hepatitis B in Cancer Patients During Immunotherapy.
Status: NOT_YET_RECRUITING
Conditions: Occult Hepatitis B Infection in Cancer Patients
Interventions: OTHER: Observational: Blood sample of HVB-specific Elispot assay, HBSAg, HBV-DNA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of De-immunized DI-Leu16-IL2 Administered Subcutaneously in Participants With B-cell NHL
Status: TERMINATED
Conditions: B-cell Non-Hodgkin Lymphoma
Interventions: DRUG: DI-Leu16-IL2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Whether BI 690517 in Combination With Empagliflozin Helps People With Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: DRUG: BI 690517|DRUG: Empagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PRS-344/S095012 (PD-L1x4-1BB Bispecific Antibody-Anticalin Fusion) in Patients With Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: PRS-344/S095012
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Efficacy of Smart Orthopedic Minimally Invasive Surgical Systems for Spinal Surgery
Status: COMPLETED
Conditions: Spine Disease|Spinal Fractures
Interventions: COMBINATION_PRODUCT: surgical robot|COMBINATION_PRODUCT: controlled approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diaphragm Ultrasound to Evaluate the Antagonistic Effect of Sugammadex
Status: UNKNOWN
Conditions: Diaphragm Ultrasonography|Liver Dysfunction|Sugammadex|Rocuronium
Interventions: DRUG: sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Randomized Controlled Multi-center Short Course Treatment for Rifampicin Resistant Tuberculosis
Status: UNKNOWN
Conditions: Tuberculosis
Interventions: DRUG: Total oral short-term therapy that includes linezolid, bedaquiline and/or cycloserine.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low VS High-fidelity Interprofessional Simulation for ABG Skills Acquisition
Status: RECRUITING
Conditions: Interprofessional Relations|Self Efficacy|Knowledge, Attitudes, Practice
Interventions: OTHER: High-fidelity interprofessional simulation|OTHER: Low-fidelity interprofessional simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Endotracheal Tube Threading Over the Fiberoptic Bronchoscope
Status: COMPLETED
Conditions: Fiberoptic Guided Intubation
Interventions: PROCEDURE: Threading on the left lip commissure|PROCEDURE: Threading on the right lip commmissure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: UARK 2013-05 A Study of Autologous Expanded Natural Killer Cell Therapy for Asymptomatic Multiple Myeloma
Status: COMPLETED
Conditions: Asymptomatic Multiple Myeloma
Interventions: DRUG: ENK Cell Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION