pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Nasogastric Tube in Pancreatic Surgery
Status: UNKNOWN
Conditions: Nasogastric Tube Decompression|Pancreatic Surgery
Interventions: PROCEDURE: NGT group|PROCEDURE: non-NGT group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nettle and Cranberry Capsules for Prevention of Urinary Tract Infection
Status: RECRUITING
Conditions: Urinary Tract Infection
Interventions: DIETARY_SUPPLEMENT: Nettle and Cranberry complex capsules|DIETARY_SUPPLEMENT: Placebo(starch)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Focused Suicide Prevention Strategy for Youth
Status: UNKNOWN
Conditions: Suicide|Suicide, Attempted|Suicidal Ideation
Interventions: BEHAVIORAL: F-SPS+UC|BEHAVIORAL: EUC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab
Status: COMPLETED
Conditions: Atherosclerotic Cardiovascular Disease
Interventions: DRUG: Alirocumab|DRUG: Placebo|DRUG: LMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Psychological Assessment of Scoliosis Patients Undergoing Surgical Management
Status: RECRUITING
Conditions: Adolescent Idiopathic Scoliosis (AIS)|Mental Health
Interventions: BEHAVIORAL: Aims to Decrease Anxiety and Pain Treatment (ADAPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Safety and Immune Response of a Meningococcal Vaccine Administered to Healthy Infants
Status: COMPLETED
Conditions: Prevention of Meningococcal Disease
Interventions: BIOLOGICAL: MenACWY Ad- (MenACWY-CRM, non adjuvanted formulation)|BIOLOGICAL: MenACWY Ad+ (MenACWY-CRM, adjuvanted formulation)|BIOLOGICAL: MenACWY PS (MenACWY-CRM, polysaccharide vaccine)|BIOLOGICAL: HBV (Hepatitis B vaccine)|BIOLOGICAL: Prevnar (pneumococcal polysaccharide serotypes 4, 9V, 14, 18C, 19F, 23F & 6B conjugated to the CRM197)|BIOLOGICAL: MMR (Measles, Mumps and Rubella vaccine)|BIOLOGICAL: DTaPHibIPV (Diphtheria, Tetanus, acellular Pertussis, H. Influenzae type b, Inactivated Poliovaccine)|BIOLOGICAL: Menjugate (Men C conjugated vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: HaemoDYNAMICs in Primary and Secondary Hypertension
Status: RECRUITING
Conditions: Primary Hypertension|Secondary Hypertension|Aortic Stenosis|Renal Insufficiency
Interventions: DRUG: Nitroglycerin 0.25 mg (single dose, no longer given since January 2017)|DRUG: Salbutamol 400 µg (single dose, no longer given since January 2017)|DRUG: L-arginine (10 min infusion, no longer given since January 2017)|DIETARY_SUPPLEMENT: Liquorice (2 weeks, glycyrrhizin 290-370 mg daily, no longer given since 2012)|DIETARY_SUPPLEMENT: Small milk casein-derived polypeptides (12 weeks daily, recordings completed 2011)|DRUG: Bisoprolol (5 mg daily for 3 weeks, recordings completed 2011)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Ubiquinol Supplementation on Ovulation Induction in Clomiphene Citrate Resistance
Status: COMPLETED
Conditions: Polycystic Ovarian Syndrome
Interventions: DRUG: Controlled ovarian stimulation by Combined Clomiphene Citrate and Ubiquinol Versus hMG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SaExten Vena Cava Filter System in Prevention of Pulmonary Embolism
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: DEVICE: SaExten vena cava filter system|DEVICE: Denali inferior vena cava filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PrEscription of Intra-Dialytic Exercise to Improve quAlity of Life in Patients With Chronic Kidney Disease
Status: COMPLETED
Conditions: End-Stage Kidney Disease
Interventions: BEHAVIORAL: INTRA-DIALYTIC EXERCISE TRAINING
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Doxycycline for Treating Pleural Effusions Related to Cancer in an Outpatient Population
Status: UNKNOWN
Conditions: Malignant Pleural Effusion
Interventions: DRUG: Doxycycline|OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gastric Emptying Times of Normal and Obese Children After Preoperative Clear Fluid Drinking: An Ultrasound Study
Status: COMPLETED
Conditions: Gastric Emptying Time
Interventions: DRUG: 5% Dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Treatment Programs for Chronic Kidney Disease-mineral and Bone Disorder and Malnutrition
Status: UNKNOWN
Conditions: Vitamin D Deficiency|Malnutrition
Interventions: DRUG: 1,25(OH)2 Vitamin D3|DRUG: Vitamin D2|DIETARY_SUPPLEMENT: low protein diet|DIETARY_SUPPLEMENT: normal protein diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Involvement of Monocytic B1 and B2 Receptors in Inflammation and Chronic Vascular Disease in Patients With Hereditary Bradykinetic Angioedema
Status: UNKNOWN
Conditions: Hereditary Bradykinetic Angioedema
Interventions: OTHER: Explorations|OTHER: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dose Escalation of BIBF 1120 Combined With Pemetrexed in Advanced Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: BIBF 1120|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Anterior Corneal Incisions on Intraoperative Floppy Iris Syndrome (IFIS) Incidence and Severity in Tamsulosin Treated Cataract Patients
Status: UNKNOWN
Conditions: Intraoperative Floppy Iris Syndrome
Interventions: PROCEDURE: anterior (more central) corneal paracentesis incision
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyper Polarized Xenon-129 MRI vs Xenon-133 Scintigraphy
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Hyperpolarized Xenon-129 MRI (Experimental)|DRUG: Radioactive Xenon-133 scintigraphy (Active Comparator)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Patch Study (Patch-augmented Rotator Cuff Repair)
Status: RECRUITING
Conditions: Rotator Cuff Tears
Interventions: DEVICE: Arthroscopic rotator cuff reconstruction using fixation with anchors augmented with a synthetic polyester patch (Pitch-Patch Tissue Reinforcement Device))|DEVICE: Arthroscopic rotator cuff reconstruction using fixation with anchors augmented without a synthetic polyester patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study for Safety and Effectiveness of RWJ-333369 (Carsibamate) for the Treatment of Diabetic Peripheral Neuropathy (DPN).
Status: COMPLETED
Conditions: Diabetic Neuropathy, Painful|Diabetic Neuralgia|Diabetic Polyneuropathy|Diabetic Mononeuropathy
Interventions: DRUG: placebo|DRUG: RWJ-333369 (carisbamate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Dry Needling in Chronic Neck Pain.
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Local Dry needling and exercise|OTHER: Distal Dry needling and exercise|OTHER: Sham dry needling and exercise|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Surgery Versus Medical Management for Resolution of Type II Diabetes
Status: COMPLETED
Conditions: Obesity|Type 2 Diabetes Mellitus
Interventions: OTHER: Laboratory evaluations, sleep study|OTHER: Best Medical Management|PROCEDURE: Roux-en-Y gastric bypass surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of the Efficacy and Safety of Inhaled Technosphere Insulin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Technosphere Insulin|DRUG: Technosphere Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of High-risk Newly Diagnosed Multiple Myeloma With Minimal Residual Disease Detection
Status: NOT_YET_RECRUITING
Conditions: Newly Diagnosed|High Risk|MRD|Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Daratumumab|DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: VRD for first-cycle induction therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Protein Breakfast on Postprandial Glycemia in T2D (PBD)
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: OTHER: Arm1: Whey protein|OTHER: Arm 2 Breakfast- other proteins|OTHER: Arm 3 Breakfast- low protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for Assessment of Safety and Efficacy of a Echinacea/Sage Spray Compared to a Chlorhexidine/Lidocaine Spray in the Treatment of Acute Sore Throats
Status: COMPLETED
Conditions: Pharyngitis
Interventions: DRUG: chlorhexidine/lidocaine|DRUG: echinacea/sage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Application of Al18F-NOTA-FAPI PET/CT in Malignant Tumors Expressing Fibroblast-activated Proteins
Status: RECRUITING
Conditions: Malignancy
Interventions: DRUG: Al18F-NOTA-FAPI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Laboratory Study Investigating How Physical Tasks and Hunger Affect Taste Perception
Status: UNKNOWN
Conditions: Food Consumption|Perseverance
Interventions: BEHAVIORAL: Simple physical task|BEHAVIORAL: Complex physical task|OTHER: Cookies|OTHER: Vegetables|BEHAVIORAL: No physical task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: C1-esterase Inhibitor (Cinryze) for Acute Treatment of Neuromyelitis Optica Exacerbation
Status: COMPLETED
Conditions: Neuromyelitis Optica
Interventions: DRUG: C1-esterase inhibitor (Cinryze)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Parasympathetic Activity in Mild to Severe Asthma With Fixed Airway Obstruction (PARASMA Study)
Status: RECRUITING
Conditions: Asthma|Airway Obstruction|Airway Remodeling|Parasympathetic Nervous System Diseases
Interventions: DRUG: Salbutamol|DRUG: Ipratropium Bromide|DRUG: Salbutamol plus Ipratropium Bromide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison on Blood Pressure Effect of an Equivalent Sodium Intake, With Different Nature, for Hypertensive Subjects
Status: UNKNOWN
Conditions: Hypertension
Interventions: DIAGNOSTIC_TEST: Phenotyping|DIETARY_SUPPLEMENT: Drug intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM
Status: RECRUITING
Conditions: Glioblastoma Multiforme (GBM)|Glioblastoma|Glioma of Brain|Glioblastoma, Adult|Brain Tumor|Brain Tumor, Primary|Brain Tumor Adult|Cancer|Brain Cancer
Interventions: DRUG: Capecitabine|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Augmenting Mental Health Support Through a Supportive Text Messaging Program
Status: RECRUITING
Conditions: Major Depressive Disorder|Generalized Anxiety Disorder|Mental Health Wellness 1
Interventions: OTHER: Mental health supportive text messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Perioperative Selective alpha1-blockers in Non-stented Ureteroscopic Laser Lithotripsy for Ureteric Stones: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Non-stented Ureteroscopic Laser Lithotripsy for Ureteric Stones
Interventions: DRUG: Tamsulosin Oral Capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring the Full Body Representation in Anorexia Nervosa and Bulimia Nervosa
Status: NOT_YET_RECRUITING
Conditions: Anorexia Nervosa/Bulimia
Interventions: BEHAVIORAL: Mental Motor Chronometry (MMC) Task Hands and Feet and Whole Body
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Addressing Disparities in Neuromodulation for Rehabilitation: A Mixed Methods Approach to Optimize Access for Underrepresented Racial Minorities
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: OTHER: taVNS Video|OTHER: Educational materials|OTHER: TMS Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Modification of the Activity of the Prefrontal Cortex by Virtual Distraction in the Lumbago
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: measurement of bilateral activity of the prefrontal cortex by a NIRS system (near infrared spectroscopy)|OTHER: completion of questionnaires|OTHER: completion of questionnaires for pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Foxy-5 as Neo-Adjuvant Therapy in Subjects With Wnt-5a Low Colon Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colon Cancer
Interventions: DRUG: Foxy-5|DRUG: FOLFOX regimen|PROCEDURE: Tumour resection (colon cancer surgery)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of IMC-1121B (Ramucirumab) With or Without Dacarbazine in Metastatic Malignant Melanoma
Status: COMPLETED
Conditions: Metastatic Malignant Melanoma
Interventions: BIOLOGICAL: IMC-1121B (ramucirumab)|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MPFC Theta Burst Stimulation as a Tool to Affect Rational Decision Making
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DEVICE: Real TBS to mPFC|DEVICE: Sham TBS to mPFC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: CLUE Study: Connective Tissue Disease Leg Ulcer Etiology Study
Status: COMPLETED
Conditions: Connective Tissue Diseases|Blood Coagulation Disorders|Leg Ulcers|Rheumatoid Arthritis|Systemic Lupus Erythematosus|Systemic Scleroderma|Mixed Connective Tissue Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Vitamin D Repletion in Vitamin D Deficient Patients With Stage 3 and 4 Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Renal Insufficiency|Proteinuria
Interventions: DRUG: Vitamin D|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protein for Premies
Status: COMPLETED
Conditions: Extreme Prematurity
Interventions: DIETARY_SUPPLEMENT: High Dose Protein (Individualized)|DIETARY_SUPPLEMENT: High Dose Protein (Standardized)|DIETARY_SUPPLEMENT: Standard Protein Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: YSPSL for Prevention of Ischemic Reperfusion Injury in Patients Undergoing Cadaveric Orthotopic Liver Transplantation
Status: UNKNOWN
Conditions: Ischemia Reperfusion Injury
Interventions: DRUG: recombinant P-selectin glycoprotein ligand Ig fusion protein|DRUG: Viaspan® and saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Duration of Ameluz Application in Acral Actinic Keratoses Response
Status: TERMINATED
Conditions: Actinic Keratoses|Photodamaged Skin
Interventions: DRUG: Ameluz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bismuth-containing Quadruple Therapy for Helicobacter Pylori Eradication
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Amoxicillin|DRUG: Clarithromycin|DRUG: Tetracycline|DRUG: Metronidazole|DRUG: Bismuth Potassium Citrate|DRUG: Colloidal Bismuth Pectin|DRUG: Vonoprazan fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcorneal Electrical Stimulation Therapy for Retinal Disease
Status: COMPLETED
Conditions: Retinitis Pigmentosa|Macula Off|Primary Open Angle Glaucoma|Hereditary Macular Degeneration|Treated Retina Detachment|Retinal Artery Occlusion|Retinal Vein Occlusion|Non-Arthritic-Anterior-Ischemic Optic-Neuropathy|Hereditary Autosomal Dominant Optic Atrophy|Dry Age Related Macular Degeneration|Ischemic Macula Edema
Interventions: DEVICE: Transcorneal Electrical Stimulation|DEVICE: DTL-electrode attached without energy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody Therapy in Treating Patients With Advanced Kidney Cancer
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: Iodine-131 radiolabeled chimeric monoclonal antibody G250 (131I-cG250)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Adapalene/BP Gel to EPIDUO® FORTE and Both to a Placebo Control in Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Adapalene/BP gel, 0.3%/2.5%|DRUG: EPIDUO® FORTE|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Myoelectric Implantable Recording Array (MIRA) in Participants With Transradial Amputation
Status: RECRUITING
Conditions: Amputation|Amputation; Traumatic, Hand
Interventions: DEVICE: Myoelectric Implantable Recording Array (MIRA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Panretinal Photo-stimulation in Proliferative Diabetic Retinopathy
Status: WITHDRAWN
Conditions: Severe Non-proliferative Diabetic Retinopathy
Interventions: DEVICE: Green Pascal|DEVICE: Yellow Pascal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Balance, Walking Speed, Quadriceps Femoris Muscle Strength and Quality of Life in Falling and Non-falling Individuals With COPD
Status: RECRUITING
Conditions: Copd
Interventions: OTHER: Changed Medical research Council,Mini Mental Test, Quadriceps Femoris muscle strength measurement,2 min walking test, fall effectiveness scale,Fall risk self-assessment scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cognition in the Study of Tamoxifen and Raloxifene
Status: COMPLETED
Conditions: Cognition|Aging
Interventions: DRUG: tamoxifen|DRUG: raloxifene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (Sustained HBsAg Loss) (B)
Status: NOT_YET_RECRUITING
Conditions: Chronic Hepatitis b|Anti-PD-1 Antibody|Peg-IFNα
Interventions: DRUG: Anti-PD-1 antibody|DRUG: NAs|DRUG: Peg-IFNα
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Pleural Fluid Penetration of Amoxicillin and Clavulanic Acid in Patients With Pleural Infections
Status: COMPLETED
Conditions: Pleural Infection|Empyema|Community-acquired Pneumonia|Pharmacokinetic|Amoxicillin
Interventions: PROCEDURE: chest tube drainage|BIOLOGICAL: antibiotic concentration in pleural fluid|DRUG: Amoxicillin + clavulanic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Construction and Application of the Visualization Training Platform Based on a Multimodal Standardized Dataset for Pain Assessment in Critically Ill Children
Status: RECRUITING
Conditions: Pediatrics|Critical Illness|Pain Measurement
Interventions: OTHER: Conventional intervention|BEHAVIORAL: Platform intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety Study of Bevacizumab and Erlotinib to Treat Primary Liver Cancer That Cannot be Removed By Surgery
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Liver Cancer
Interventions: DRUG: Bevacizumab (Avastin)|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Group EMDR Intervention on Narrative Complexity and Specificity of Autobiographical Memories: the Hug the Child Study (HTC)
Status: COMPLETED
Conditions: Child, Only|Narration|Memory Dysfunction|Distress, Emotional|Cognitive Change
Interventions: BEHAVIORAL: Group EMDR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Absorption, Metabolism, Excretion and Mass Balance After a Single Dose Administration of MK-0941 (MK-0941-016)(COMPLETED)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: MK-0941
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Frontalis Flap Advancement Versus Frontalis Sling Operations in Mangment of Congenital Blepharoptosis
Status: COMPLETED
Conditions: Unrecognized Condition
Interventions: PROCEDURE: Frontalis flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Transvaginal NOTES Cholecystectomy: Phase I/II Mexico Clinical Trial
Status: COMPLETED
Conditions: Cholelithiasis
Interventions: PROCEDURE: Transvaginal NOTES cholecystectomy|PROCEDURE: Laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemoembolization Using Irinotecan in Treating Patients With Liver Metastases From Metastatic Colon or Rectal Cancer
Status: TERMINATED
Conditions: Liver Metastases|Mucinous Adenocarcinoma of the Colon|Mucinous Adenocarcinoma of the Rectum|Recurrent Colon Cancer|Recurrent Rectal Cancer|Signet Ring Adenocarcinoma of the Colon|Signet Ring Adenocarcinoma of the Rectum|Stage IV Colon Cancer|Stage IV Rectal Cancer
Interventions: COMBINATION_PRODUCT: irinotecan-eluting beads|PROCEDURE: hepatic artery embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen Alone in Subjects With Advanced Digestive System Neoplasms
Status: RECRUITING
Conditions: Digestive System Neoplasms
Interventions: BIOLOGICAL: iNeo-Vac-R01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SCI Acute Intermittent Hypoxia and Non-Invasive Spinal Stimulation Combined With Gait Training
Status: RECRUITING
Conditions: Spinal Cord Injuries|Spinal Cord Diseases
Interventions: DEVICE: Acute Intermittent Hypoxia + Non Invasive Spinal Cord Stimulation + Gait Training|OTHER: Sham Acute Intermittent Hypoxia + Non Invasive Spinal Cord Stimulation + Gait Training|OTHER: Sham Acute Intermittent Hypoxia + Sham Non Invasive Spinal Cord Stimulation + Gait Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Carbon Dioxide Insufflation During Colonoscopy With Consecutive Esophagogastroduodenoscopy in Reduction of Abdominal Pain in Sedated Outpatients
Status: COMPLETED
Conditions: Pain
Interventions: OTHER: bowel insufflation gas|OTHER: bowel insufflation gas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes
Status: NOT_YET_RECRUITING
Conditions: Lung Transplant; Complications|Lung Transplant; Infection or Inflammation|Lung Transplant Rejection|Lung Transplant Failure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Incidence of Residual Neuromuscular Blockade in Fraility in OncoGynae Surgery
Status: RECRUITING
Conditions: Frailty|Neuromuscular Blockade|General Anesthetic Drug Adverse Reaction|Gynecologic Cancer|Surgical Complication
Interventions: DIAGNOSTIC_TEST: Train of four nerve stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of a Brief Tobacco Intervention in the US Military
Status: COMPLETED
Conditions: Tobacco Use|Tobacco Smoking|Smoking, Cigar|Smoking, Pipe|Smoking, Hookah|Nicotine Dependence
Interventions: BEHAVIORAL: BTI|BEHAVIORAL: Cigarette smoking military tailored pamphlet|BEHAVIORAL: Standard smoking cessation intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of 20% Betulinic Acid Ointment for Treatment of Dysplastic Nevi (Moderate to Severe Dysplasia)
Status: WITHDRAWN
Conditions: Dysplastic Nevus Syndrome
Interventions: DRUG: 20% betulinic acid ointment|DRUG: BA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EXercise as TReatment for osteoArthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: NEMEX and education + strength training|OTHER: NEMEX and education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiation Therapy in Preventing Recurrence in Patients With Breast Cancer After Surgery
Status: COMPLETED
Conditions: Stage I Breast Cancer AJCC v7|Stage IA Breast Cancer AJCC v7|Stage IB Breast Cancer AJCC v7|Stage II Breast Cancer AJCC v6 and v7|Stage IIA Breast Cancer AJCC v6 and v7|Stage IIB Breast Cancer AJCC v6 and v7|Stage IIIA Breast Cancer AJCC v7
Interventions: RADIATION: Hypofractionated Radiation Therapy|OTHER: Quality-of-Life Assessment|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioavailability Study of Candesartan Cilexetil 16mg Tablet Under Fasting Conditions
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Candesartan cilexetil (GW615775, Test formulation)|DRUG: Candesartan cilexetil (Reference treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic Supplement as Treatment for Students With ADHD
Status: UNKNOWN
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of PF-05221304 in Subjects With Varying Degrees of Hepatic Impairment
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: PF-05221304
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Early Feeding Following Ligation of Acute Bleeding Varices
Status: UNKNOWN
Conditions: Varices
Interventions: DIETARY_SUPPLEMENT: Delayed feeding|DIETARY_SUPPLEMENT: Dealyed feeding|DIETARY_SUPPLEMENT: Early feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving Symptom Trajectories of Tic Disorders and Co-occurring Diagnoses: The Role of Integrative Intensive Intervention
Status: COMPLETED
Conditions: Tic Disorder, Childhood|Comorbidities and Coexisting Conditions
Interventions: BEHAVIORAL: Combination of Comprehensive Behavioral Intervention for Tics (CBIT) and Evidence-based interventions for co-occurring diagnoses (i.e., Cognitive Behavioral Therapy, Behavioral Parent Training)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Oral Quinine and Artemether-Lumefantrine in the Treatment of Uncomplicated Malaria in Ugandan Children
Status: UNKNOWN
Conditions: Uncomplicated Malaria
Interventions: DRUG: artemether-lumefantrine|DRUG: Oral quinine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Timing of Dilation Tracheostomy in Mechanically Ventilated Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: TERMINATED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: PROCEDURE: Percutaneous dilation tracheostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sinovac, Pandemic Influenza A/H1N1 Vaccine in 6 to 35 Months Infants
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Pandemic influenza A/H1N1 vaccine|BIOLOGICAL: Pandemic influenza A/H1N1 vaccine|BIOLOGICAL: Seasonal trivalent vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: First in Man Clinical Study to Evaluate Safety and Tolerability of an Oncolytic Adenovirus in Prostate Cancer Patients.
Status: ACTIVE_NOT_RECRUITING
Conditions: Adenocarcinoma of the Prostate
Interventions: BIOLOGICAL: ORCA-010
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness and Safety of XELOX and Tislelizumab + PLD for Resectable Gastric Cancer (LidingStudy)
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: PLD|DRUG: Oxaliplatin|DRUG: Capecitabine|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IV Dexamethasone for Prolongation of Peripheral Nerve Block
Status: COMPLETED
Conditions: Anesthesia, Conduction
Interventions: DRUG: IV dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Coronary Calcification Study
Status: COMPLETED
Conditions: Chronic Kidney Disease|Vitamin D Deficiency|Coronary Calcification|Disorders of Calcium and Bone Metabolism
Interventions: DRUG: Calcitriol (Rocaltrol®)|DRUG: Paricalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomised Trial Evaluating Continuous Subcutaneous Infusion of Formulations of NN1218 and NovoLog® in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: Faster-acting insulin aspart|DRUG: Faster-acting insulin aspart|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cherry Concentrate on Brain Activation and Perfusion in Healthy Older Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Cherry concentrate|DIETARY_SUPPLEMENT: Placebo concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized, Double-Blind, Placebo Controlled Study of l-Leucovorin in Combination With Trimethoprim / Sulfamethoxazole in the Therapy of Pneumocystis Carinii Pneumonia in Patients With the Acquired Immunodeficiency Syndrome
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Trimethoprim|DRUG: Sulfamethoxazole|DRUG: Leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Hamstring Muscle in Patients With Low-back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Dry needling in hamstring muscle trigger points|OTHER: Dry needling in hamstring muscle not trigger points
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effect of Macitentan on the Electrocardiogram (ECG) in Healthy Male and Female Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Moxifloxacin 400 mg|DRUG: Macitentan 10 mg|DRUG: Macitentan 30 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effects of Different Centrifuged Platelet Concentrates on Bone Remodelling Around Dental Implants
Status: COMPLETED
Conditions: Edentulous Jaw|Bone Loss, Alveolar|Resorption, Bone
Interventions: PROCEDURE: Application of concentrated growth factor with dental implants|PROCEDURE: Application of advanced platelet rich fibrin with dental implants|PROCEDURE: Control side of concentrated growth factor study group|PROCEDURE: Control side of advanced platelet rich fibrin study group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effects of Psyllium on Blood Glucose
Status: COMPLETED
Conditions: Healthy Men
Interventions: DIETARY_SUPPLEMENT: 3.4 g psyllium|DIETARY_SUPPLEMENT: 6.8 g psyllium|DIETARY_SUPPLEMENT: 6.8 g psyllium|OTHER: Meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multi-modal Neuroimaging in Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: BEHAVIORAL: assessment of memory|BIOLOGICAL: circulating tPA dosage|GENETIC: ApoE4|OTHER: Brain imaging examination MRI and PET examinations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment Protocol for Newky Diagnosed Adult Ph Positive ALL
Status: NOT_YET_RECRUITING
Conditions: Lymphoblastic Leukemia|Philadelphia-Positive ALL|Adult ALL
Interventions: DRUG: Vincristine|DRUG: Dexamethasone|DRUG: Imatinib|DRUG: Cytarabine|DRUG: Mercaptopurine|DRUG: Methotrexate|DRUG: Ponatinib|PROCEDURE: allogeneic stem cell transplantation|PROCEDURE: Total body irradiation|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Long-Term Treatment With Atorvastatin in Patients With Primary Biliary Cirrhosis
Status: COMPLETED
Conditions: Primary Biliary Cirrhosis|Hypercholesterolemia
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Insight Into Migraine Pathophysiolgy and Galcanezumab Mechanisms of Action
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Migraine
Interventions: DRUG: Emgality 120 MG in 1 ML Prefilled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety of and Immune Response to Two Influenza Vaccines in HIV Infected Children and Adolescents
Status: COMPLETED
Conditions: HIV Infections|Influenza
Interventions: BIOLOGICAL: Cold-adapted live attenuated influenza vaccine (FluMist)|BIOLOGICAL: Inactivated influenza vaccine (IAIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Effect of Omalizumab on Improving the Tolerability of Specific Immunotherapy in Patients With Persistent Allergic Asthma
Status: COMPLETED
Conditions: Allergic Asthma
Interventions: DRUG: Placebo|DRUG: Omalizumab|DRUG: Immunotherapy|DRUG: Immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Cetuximab Plus Irinotecan in Patients With EGFR-detectable Metastatic Colorectal Carcinoma
Status: COMPLETED
Conditions: Colorectal Carcinoma
Interventions: DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Potential Drug-Drug Interaction Between Efavirenz and Danoprevir With Low Dose Ritonavir in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: danoprevir|DRUG: efavirenz|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Co-administration of Canagliflozin 300 mg and Phentermine 15 mg With Placebo in the Treatment of Non-Diabetic Overweight and Obese Participants
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Canagliflozin|DRUG: Phentermine|DRUG: Matching Placebo to Canagliflozin|DRUG: Matching Placebo to Phentermine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Methylphenidate as Treatment Option of Fatigue in Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis|Fatigue
Interventions: DRUG: Methylphenidate modified release|DRUG: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Determine the Effectiveness of Transesophageal Lung Ultrasound Guided Recruitment Maneuver in Cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Bypass Surgery
Interventions: PROCEDURE: Transesophageal lung ultrasound (TELUS) guided recruitment maneuver|OTHER: Manual bag lung reinflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Antiviral Activity of IONIS-HBVRx in Treatment-Naïve Patients With Chronic HBV Infection
Status: COMPLETED
Conditions: Hepatitis B|Chronic Hepatitis B Atypical
Interventions: DRUG: IONIS-HBVRx|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Shared Decision Making for Kidney Transplant Candidates to Plan for an Organ Offer Decision
Status: NOT_YET_RECRUITING
Conditions: End Stage Renal Disease|End-Stage Kidney Disease|Kidney Transplantation|Esrd
Interventions: BEHAVIORAL: Kidney Offer Shared Decision Making
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Laughter Yoga on Pain and Comfort in Individuals Diagnosed With Migraine
Status: UNKNOWN
Conditions: Pain, Head
Interventions: BEHAVIORAL: laughter yoga practice|BEHAVIORAL: watching funny videos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Personalized Targeted IMMUNOtherapy-based Regimens in Recurrent GASTric Adenocarcinoma (IMMUNOGAST)
Status: UNKNOWN
Conditions: Gastric Adenocarcinoma|Metastatic Gastric Cancer|Metastatic Adenocarcinoma|Advanced Gastric Carcinoma
Interventions: DRUG: Atezolizumab + Ipatasertib|DRUG: Atezolizumab + Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Project Relief: Developing Brain Stimulation as a Treatment for Chronic Pain
Status: COMPLETED
Conditions: Chronic Pain|Chronic Lower Back Pain|Back Pain|Opioid Use|Opiate Dependence|Pain, Chronic|Neuropathic Pain|Chemotherapy-induced Peripheral Neuropathy
Interventions: DEVICE: Real TBS to the mPFC|DEVICE: Sham TBS to the mPFC|DEVICE: Real TBS to the MC|DEVICE: Sham TBS to the MC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Cohort Follow-up of Survivors of Hospitalization for COVID-19 During the 2nd Wave of the Epidemic in France
Status: UNKNOWN
Conditions: Sequelae|Fibrosis|Post-COVID Syndrome|Post-traumatic Stress Disorder
Interventions: OTHER: Teleconsultation|OTHER: Outpatient clinic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Evaluation of Vanguard DD RP
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Osteoarthritis|Post-traumatic Osteoarthritis|Rheumatoid Arthritis
Interventions: DEVICE: Cementless Vanguard DD RP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Suicide in African American Adolescents
Status: ACTIVE_NOT_RECRUITING
Conditions: Suicide
Interventions: BEHAVIORAL: Robinson's Culturally Adapted Coping with Stress Course (A-CWS)|BEHAVIORAL: Standard Care Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Indian Post Marketing Study of Mealtime Insulin, Fiasp®, to Evaluate Its Safety and Effectiveness in Patients With Diabetes Mellitus in Routine Clinical Practice
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: Faster-acting insulin aspart
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Dose-ranging Study in Patients With Diabetic Peripheral Neuropathic Pain (DPNP)
Status: RECRUITING
Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: DRUG: Placebo (blinded)|DRUG: LX9211 (blinded)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minirigid Versus Conventional Rigid Thoracoscopy in Undiagnosed Pleural Effusions
Status: RECRUITING
Conditions: Pleural Effusion
Interventions: DEVICE: Mini-thoracoscopy|DEVICE: Conventional rigid thoraoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetic Study of Belviq in Adult Korean Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Belviq 10mg|DRUG: Belviq 20mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Synbiotic Consumption on Glycemic, Inflammatory Markers and Body Composition on Prediabetic and Diabetic Patients
Status: UNKNOWN
Conditions: Dietary Supplements
Interventions: DIETARY_SUPPLEMENT: Synbiotic group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT