pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Induction Chemotherapy Followed by Radiotherapy Alone or Concurrent Chemoradiotherapy in Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Locally Advanced Nasopharyngeal Carcinoma
Interventions: DRUG: Docetaxel|DRUG: Cisplatin|RADIATION: IMRT/TOMO|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Combining Hydroxyurea (HU) With Didanosine (ddI) and Stavudine (d4T) for Treatment of HIV-Infected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Hydroxyurea|DRUG: Stavudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: FACTORIAL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Vildagliptin in Older Adults With Diabetes and Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DRUG: Vildagliptin 50 MG Oral Tablet|DRUG: Metformin Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Hematopoietic Stem Cell Transplantation in High Risk Patients With Fanconi Anemia
Status: COMPLETED
Conditions: Fanconi Anemia
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: filgrastim|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|DRUG: methylprednisolone|BIOLOGICAL: Hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regorafenib in Reducing Recurrence in Patients With Non-metastatic Rectal Cancer Who Have Completed Curative-Intent Treatment
Status: WITHDRAWN
Conditions: Rectal Adenocarcinoma|Stage IIA Rectal Cancer|Stage IIB Rectal Cancer|Stage IIC Rectal Cancer|Stage IIIA Rectal Cancer|Stage IIIB Rectal Cancer
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: De-escalation Adjuvant Chemo in HER2+/ER-/Node-neg Early BC Patients Who Achieved pCR After Neoadjuvant Chemo & Dual HER2 Blockade
Status: SUSPENDED
Conditions: HER2-positive Breast Cancer|ER-Negative Breast Cancer|PR-Negative Breast Cancer|Node-negative Breast Cancer
Interventions: DRUG: Pertuzumab and tratuzumab fixed dose combination|DRUG: Trastuzumab emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IV Clinical Trial to Evaluate the Efficacy and Safety of Jublia® in Mild to Moderate Toenail Onychomycosis
Status: COMPLETED
Conditions: Mild to Moderate Onychomycosis Due to Dermatophyte
Interventions: DRUG: Jublia®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid Arthritis
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Upadacitinib|DRUG: Adalimumab|DRUG: Upadacitinib Matching Placebo|DRUG: Adalimumab Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Stretching and Relaxation Exercises on Anxiety in Individuals With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: Cervical Extensor Stretch|OTHER: Cervical Extensor Stretch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Randomized Controlled Trial Comparing Postoperative Pain Following TAH With GA vs. Combined GA + SAB
Status: WITHDRAWN
Conditions: Hysterectomy
Interventions: DRUG: General Anesthesia + Spinal anesthesia combined|DRUG: General Anesthesia (control group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NSAID RCT for Prevention of Altitude Sickness
Status: UNKNOWN
Conditions: Spectrum of Altitude-associated Neurologic Forms of Altitude
Interventions: DRUG: Ibuprofen 600mg orally three times daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Motivational Interviewing: An Experiential Online Training Tool
Status: COMPLETED
Conditions: Substance Use Disorders|Chronic Mental Disorder|HIV/AIDS
Interventions: BEHAVIORAL: Motivational Interviewing Simulator (SIM)|BEHAVIORAL: Motivational Interviewing eBook (eBook)|BEHAVIORAL: Motivational Interviewing Training (MI Training)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Glucose, Whey Protein and Time to the Next Meal on Mealtime Food Intake in Children
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: water with glucose|DIETARY_SUPPLEMENT: water and whey protein|DIETARY_SUPPLEMENT: water with noncaloric sweetener
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Drug-Drug Interaction Study to Evaluate the Effect of AL-794 on the Pharmacokinetics of Oseltamivir and JNJ-63623872
Status: COMPLETED
Conditions: Influenza in Humans
Interventions: DRUG: AL-794|DRUG: Oseltamivir|DRUG: Digoxin|DRUG: Midazolam|DRUG: Pitavastatin|DRUG: JNJ-63623872
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic of CC-95775 in Subjects With Advanced Solid Tumors and Relapsed/Refractory Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: CC-95775
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hair Regeneration in Androgenetic Alopecia
Status: ACTIVE_NOT_RECRUITING
Conditions: Androgenetic Alopecia
Interventions: DRUG: Minoxidil Topical|OTHER: Secretome from adipose-derived stem cells|COMBINATION_PRODUCT: Combination of minoxidil and secretome from adipose-derived stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PMS Evaluation of Safety and Efficacy of the MID-C System 5 Years Post-implantation in AIS
Status: WITHDRAWN
Conditions: Adolescent Idiopathic Scoliosis
Interventions: DEVICE: MID-C System -Minimal invasive deformity correction system for the treatment of AIS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1 Antibody Versus Best Supportive Care After Chemoradiation in Locoregionally Advanced Nasopharyngeal Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Nasopharyngeal Neoplasms
Interventions: DRUG: Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Electronic Brachytherapy for Cutaneous Basal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Basal Cell
Interventions: DEVICE: Electronic Brachytherapy (6,1 Gy)|DEVICE: Electronic Brachytherapy (7 Gy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine, Lidocaine and Combination for Postoperative Analgesia in Open Liver Resection
Status: COMPLETED
Conditions: Hepatectomy
Interventions: DRUG: Lidocaine|DRUG: Ketamine|DRUG: Lidocaine+ketamine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Salmeterol Xinafoate and Fluticasone Propinate Powder for Inhalation for Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: DRUG: Salmeterol Xinafoate and Fluticasone Propinate Powder|DRUG: Seretide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Vitamin C Supplement vs Spinal Manipulation to Treatment in Lateral Epicondylitis
Status: UNKNOWN
Conditions: Lateral Epicondylitis|Tennis Elbow
Interventions: COMBINATION_PRODUCT: Vitamin C|COMBINATION_PRODUCT: spinal manipulation|COMBINATION_PRODUCT: Transcutaneous electrical nerve stimulation (TENS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of PET 18F-Fludarabine for the Initial Assessment and End-treatment of Symptomatic Multiple Myeloma Patients
Status: RECRUITING
Conditions: Myeloma
Interventions: DRUG: 18F-Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety Study of Rimegepant in Episodic Migraine Prevention With Multiple Dosing Regimens
Status: ACTIVE_NOT_RECRUITING
Conditions: Migraine
Interventions: DRUG: Rimegepant 75mg daily dosing|DRUG: Rimegepant 75mg every other day dosing|DRUG: Placebo comparator dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Open Label, Multiple Arm Study of AUY922, BYL719, INC280, LDK378 and MEK162 in Chinese Patients With Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Adenocarcinoma Lung Cancer; Squamous Cell Lung Carcinoma
Interventions: DRUG: BYL719|DRUG: INC280|DRUG: LDK378|DRUG: MEK162
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Favipiravir +/- Nitazoxanide: Early Antivirals Combination Therapy in COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Favipiravir|DRUG: Nitazoxanide|OTHER: Nitazoxanide Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Uncovering a Novel Therapeutic Target to Reduce Dementia Risk in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease|Mild Cognitive Impairment|Memory Impairment
Interventions: DRUG: Levetiracetam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double Simultaneous Uterotonic Agents Versus Single Agent Regimen to Prevent Early Postpartum Hemorrhage
Status: RECRUITING
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Sublingual Misoprostol|DRUG: IV Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Artificial Intelligence-augmented Perioperative Clinical Decision Support
Status: RECRUITING
Conditions: ASA Class III/IV Patients|Surgery|Clinical Decision Support Systems
Interventions: OTHER: Electronic Clinical Decision Support Application|OTHER: Standard procedures of the hospital and Sham Clinical Decision Support Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Evaluation of the Efficiency of Tailored Dietary Advice in Improving the Nutrient Adequacy of the Diet of French Pregnant Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Pregnancy
Interventions: BEHAVIORAL: Tailored dietary advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Metformin Hydrochloride in Preventing Esophageal Cancer in Patients With Barrett Esophagus
Status: COMPLETED
Conditions: Barrett Esophagus|Esophageal Cancer
Interventions: DRUG: metformin hydrochloride|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Outcomes of Multiple Platforms for Assisted Robotic-Kidney (COMPAR-K)
Status: RECRUITING
Conditions: Renal Carcinoma
Interventions: DEVICE: DaVinci RAPN|DEVICE: Hugo RAS RAPN|DEVICE: Versius® RAPN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Peritoneal Dialysis vs Furosemide for Acute Kidney Injury After Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: Furosemide|PROCEDURE: Peritoneal Dialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ASLAN001 in Combination With Oxaliplatin and Capecitabine or Oxaliplatin and 5-FU With Leucovorin
Status: UNKNOWN
Conditions: Solid Tumors
Interventions: DRUG: ASLAN001+ CAPOX (Oxaliplatin, capecitabine)|DRUG: ASLAN001 + mFolfox6 (5-FU, leucovorin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Softgel KOVIR (TD0068) in the Combination Regimen With Background Treatment in COVID-19 Patients (KOVIR)
Status: UNKNOWN
Conditions: COVID-19
Interventions: DIETARY_SUPPLEMENT: KOVIR (TD0068) oral softgel|DIETARY_SUPPLEMENT: Placebo oral softgel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Integrating Smart Ring Wearable Technology in Pregnancy Health Monitoring (I-SMART)
Status: NOT_YET_RECRUITING
Conditions: Pregnancy
Interventions: OTHER: Integrating Smart Ring Wearable Technology in Pregnancy Health Monitoring (I-SMART)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Denosumab Biosimilar Injection in Post Menopausal Women With Osteoporosis
Status: RECRUITING
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: Denosumab|DRUG: Denosumab-Ref
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Use of Antibiotics for Through and Through Lacerations of the Lip
Status: TERMINATED
Conditions: Through-and-through Lip Lacerations
Interventions: DRUG: keflex|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Isatuximab, Velcade, and Dexamethasone in Patients With Multiple Myeloma and Severe KIDNEY Disease
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Isatuximab|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of MK-0663/Etoricoxib in Postorthopedic Knee Replacement Surgery Pain (MK-0663-098)
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Etoricoxib 90 mg|DRUG: Etoricoxib 120 mg|DRUG: Ibuprofen 600 mg|DRUG: Matching Placebo for Etoricoxib 120 mg|DRUG: Matching Placebo for Etoricoxib 90 mg|DRUG: Matching Placebo for Ibuprofen|DRUG: Morphine|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of "Aquoral Lipo" Artificial Tears in Contact Lens Wearers With Discomfort
Status: RECRUITING
Conditions: Contact Lens Complication
Interventions: OTHER: Aquoral Lipo (Esteve)|OTHER: Hyabak (Thea)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Presbyopia-correcting Intraocular Lenses in Eyes With Previous Corneal Refractive Surgery
Status: UNKNOWN
Conditions: Cataract|Presbyopia
Interventions: DEVICE: Use Multifocal and Extended Depth-of-Focus Intraocular Lenses(IOLs)|DEVICE: Use Monofocal intraocular lenses(IOLs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide, Rituximab, Cyclophosphamide, and Dexamethasone in Treating Patients With Previously Untreated Low-Grade Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: dexamethasone|DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Safety and Tolerability of NOV03 (Perfluorohexyloctane) in Subjects Who Completed Trial NVU-003 (Kalahari Study)
Status: COMPLETED
Conditions: Dry Eye Disease (DED)
Interventions: DRUG: NOV03
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing VERSAJET With Conventional Surgical Procedures in the Removal of Unhealthy Tissue From Lower Limb Ulcers
Status: COMPLETED
Conditions: Diabetic Foot|Varicose Ulcer|Pressure Ulcer
Interventions: DEVICE: Versajet Hydrosurgery System|PROCEDURE: Conventional surgical debridement techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Peripheral Stem Cell Transplantation Followed by Immunotherapy in Treating Patients With Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: recombinant interferon alfa|BIOLOGICAL: sargramostim|BIOLOGICAL: therapeutic autologous lymphocytes|DRUG: carmustine|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: gemcitabine hydrochloride|DRUG: melphalan|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: in vitro-treated peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Treatment With TNF Inhibitor and Pamidronate in AS Patients: Effect on the Radiographic Progression
Status: UNKNOWN
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Pamidronate|OTHER: Placebo (NaCl 0.9%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Double-blind Extension of HORIZON Pivotal Fracture Trial (Zoledronic Acid in the Treatment of Postmenopausal Osteoporosis)
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Zoledronic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Salpingectomy at Cesarean Delivery for Ovarian Cancer Reduction (SCORE)
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: PROCEDURE: Standard postpartum tubal ligation|PROCEDURE: Complete Salpingectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Scalp Lotion Toimprove Sensitive Scalp Syndrome
Status: COMPLETED
Conditions: Alopecia|Sensitive Skin
Interventions: OTHER: Piroctone Olamine (PO), 2,4 Diaminopyrimidine oxide (2.4 DA) and Vichy mineralizing water
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Pulmonary Safety and Pharmacokinetics of Zolmitriptan Inhalation Powder
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: CVT-427 (zolmitriptan inhalation powder)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperatively Assessed Biomarker I-FABP Level for Prediction of Acute Mesenteric Ischemia and Its Correlation With Acute Kidney Injury, Followed by Extracorporeal Circulation (aMIKI)
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiac Surgery With Cardiopulmonary Bypass|Acute Mesenteric Ischemia|Acute Kidney Injury|Non-Occlusive Mesenteric Ischaemia
Interventions: OTHER: observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SonoVue Guided Prostate Biopsy
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Contrast-enhanced ultrasound guided biopsy|PROCEDURE: ultrasound guided systematic biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cholecalciferol Supplementation in Critically Ill Patients With Severe Vitamin D Deficiency.
Status: TERMINATED
Conditions: Vitamin D Deficiency|Critical Illness
Interventions: DRUG: Cholecalciferol|OTHER: Milk (Nestle)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Caffeine Versus Placebo for Spinal Headaches
Status: COMPLETED
Conditions: Post Dural Puncture Headache
Interventions: DRUG: Caffeine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genetic Polymorphism and OROS-Methylphenidate Treatment in Attention Deficit Hyperactivity Disorder(ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: OROS-methylphenidate (Concerta)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of D1+ Versus D2 Distal Gastrectomy for Stage IB & II Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Adenocarcinoma
Interventions: PROCEDURE: D2 distal subtotal gastrectomy|PROCEDURE: D1+ distal subtotal gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Electrical Stimulation and Motor Control
Status: COMPLETED
Conditions: Instability; Back
Interventions: OTHER: Combined NMES and motor control|OTHER: Motor control and placebo NMES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Vortioxetine (Lu AA21004) for Treatment of Generalized Anxiety Disorder in Adults.
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: Vortioxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Safety and Efficacy of Recombinant Von Willebrand Factor (rVWF) in the Treatment of Bleeding Episodes in Von Willebrand Disease (VWD)
Status: COMPLETED
Conditions: Von Willebrand Disease
Interventions: BIOLOGICAL: Recombinant von Willebrand factor (rVWF)|DRUG: Placebo|BIOLOGICAL: Recombinant factor VIIII (rFVIII)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of [11C]RO6924963, [11C]RO6931643, and [18F]RO6958948 as Tracers for Positron Emission Tomography (PET) Imaging of Tau in Healthy and Alzheimer's Disease (AD) Participants
Status: COMPLETED
Conditions: Alzheimer's Disease, Healthy Volunteer
Interventions: DRUG: [11C]RO6924963|DRUG: [11C]RO6931643|DRUG: [18F]RO6958948
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treating Corneal Thinning Conditions With CCL Vario Riboflavin (CXL)
Status: NOT_YET_RECRUITING
Conditions: Keratoconus, Unstable
Interventions: DRUG: Riboflavin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triple Injection Peri-sartorius (TIPS) Block
Status: COMPLETED
Conditions: Knee Disease|Nerve Pain
Interventions: PROCEDURE: ultrasound guided triple injection peri-sartorius block|PROCEDURE: Femoral Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of an Insulin Infusion Conversion Equation (IICE) to Control Blood Glucose in Hospitalized Patients
Status: COMPLETED
Conditions: Glucose, Blood
Interventions: OTHER: IICE Dosing|OTHER: Healthcare Provider dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Spirulina Supplementation on Overweight or Obese Adults
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Spirulina|OTHER: diet therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accelerating Colorectal Cancer Screening Through Implementation Science in Appalachia
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Multi-level intervention to increase CRC screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Study of Patients Receiving High-Dose Rate Brachytherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Cancer|Endometrial Cancer|Esophageal Cancer|Prostate Cancer|Biliary Cancer
Interventions: RADIATION: HDR Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fuchs' Torsional Phaco Study
Status: COMPLETED
Conditions: Fuchs' Endothelial Dystrophy|Phacoemulsification
Interventions: PROCEDURE: Phacoemulsification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation Of Balance Function In Patients With Persistent Postural Perceptual Dizziness.
Status: NOT_YET_RECRUITING
Conditions: Persistent Postural Perceptual Dizziness
Interventions: OTHER: Rehabilitation by optokinetic stimulation and virtual reality exercises .
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimal Invasive Rehabilitation of Tooth Loss in the Anterior Segment
Status: WITHDRAWN
Conditions: Unsatisfactory or Defective Restoration of Tooth
Interventions: DEVICE: metal-ceramic RBFDP|DEVICE: all-ceramic RBFDP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Brief Behavioral Activation for the Treatment of Depression in Older Adult Cancer Survivors
Status: RECRUITING
Conditions: Survivorship
Interventions: BEHAVIORAL: Behavioral Activation|BEHAVIORAL: Supportive Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Methylphenidate and Non-invasive Brain Stimulation on Inhibitory Control in Children With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Methylphenidate|DEVICE: anodal tDCS|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Reducing Disparities in Access to kidNey Transplantation (RaDIANT) Community Study
Status: COMPLETED
Conditions: Kidney Disease
Interventions: BEHAVIORAL: Behavioral Interventions for Dialysis Facilities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of the Efficacy of the Ultrasound With Fluoroscopy in Guidance of Lumbar Sympathetic Block
Status: UNKNOWN
Conditions: Complex Regional Pain Syndrome|Postherpetic Neuralgia|Diabetic Polyneuropathy|Peripheral Neuropathy
Interventions: PROCEDURE: 24G intravenous route for Lumbar Sympathetic Block (LSB):|DEVICE: 15-cm Chiba needle for Lumbar Sympathetic Block (LSB)|DEVICE: Ultrasound for Lumbar Sympathetic Block (LSB)|DEVICE: Fluoroscope for Lumbar Sympathetic Block (LSB)|DRUG: 10 ml of 0.25% levobupivacaine injection for LSB|PROCEDURE: Temperature measurement for Lumbar Sympathetic Block (LSB)|PROCEDURE: Postprocedure care for LSB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pantoprazole in Patients Older Than 18 Years Who Have Symptoms of Non-erosive Reflux or Gastroesophageal Reflux Disease (BY1023/DE-004)
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Egg Consumption on Cardiometabolic Health in Prediabetic Subjects.
Status: COMPLETED
Conditions: PreDiabetes
Interventions: OTHER: Egg based breakfast foods|OTHER: Non-egg based breakfast foods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Fluvastatin or Valsartan and Their Combination in Dyslipidemic Patients With Hypertension and Endothelial Dysfunction
Status: COMPLETED
Conditions: Hypertension|Dyslipidemia
Interventions: DRUG: valsartan, fluvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Cognitive Reappraisal Intervention for Suicide Prevention
Status: RECRUITING
Conditions: Suicide Prevention
Interventions: BEHAVIORAL: Cognitive Reappraisal Intervention for Suicide Prevention|BEHAVIORAL: Supportive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Allogeneic Hematopoietic Stem Cell Transplantation for 4/M Neuroblastoma
Status: NOT_YET_RECRUITING
Conditions: Neuroblastoma
Interventions: DRUG: Anti Thymocyte Globulin|DRUG: Fludarabine|DRUG: Cyclophosphamide injection|DRUG: Topotecan|DRUG: Melphalan|DRUG: Thiotepa|DRUG: Busulfan|DRUG: Cyclosporine|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Radioactive Seed Localization to Standard Procedure for Non-palpable Breast Cancers
Status: COMPLETED
Conditions: Breast Cancer Invasive Nos|Stage 0 Breast Carcinoma
Interventions: PROCEDURE: radioguided seed localization for nonpalpable breast cancers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Partially Covered Metal Stents Efficacy in Biliary Drainage of Malignant Extra-hepatic Biliary Obstruction
Status: UNKNOWN
Conditions: Biliary Obstruction
Interventions: DEVICE: Biliary drainage with PC-SEMS|DEVICE: Biliary drainage with U-SEMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capsule Endoscopy vs. Push Enteroscopy in Occult Gastrointestinal Bleeding OGIB
Status: COMPLETED
Conditions: Occult Gastrointestinal Bleeding
Interventions: PROCEDURE: Capsule GIVEN IMAGING LTD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study of Elemene in Treating Patients With Refractory Glioblastoma
Status: UNKNOWN
Conditions: Refractory Glioblastoma
Interventions: DRUG: Elemene|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy for Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Solid Malignancies|Non-Hodgkin's Lymphoma
Interventions: DRUG: AQ4N
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving the Function of the Foot by Core Foot System (CFS) Exercise Theory in Patients After Hallux Valgus Surgical Procedure
Status: NOT_YET_RECRUITING
Conditions: Hallux Valgus
Interventions: PROCEDURE: Scarf osteotomy for Hallux Valgus deformity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot MRI Study on Osteopathic Manipulation for Myofascial Pain Syndrome
Status: NOT_YET_RECRUITING
Conditions: Myofascial Pain Syndrome
Interventions: OTHER: Osteopathic Manipulation Treatment - Scapular Release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Study Evaluating the Efficacy of Tacrolimus Extended Release Tablets to Twice Daily Tacrolimus Dosing Regimen
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Transplant Rejection|Graft Failure|Compliance, Patient
Interventions: DRUG: Envarsus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PF-00299804 in Adult Patients With Relapsed/Recurrent Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma|GBM|Glioblastoma Multiforme
Interventions: DRUG: PF-00299804
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Predictive Model for the Risk of Metastatic Disease in PPGLs, a Retrospective Cohort Study
Status: NOT_YET_RECRUITING
Conditions: Paraganglioma|Pheochromocytoma|Genetic Predisposition to Disease|Pathology|Somatic Mutation|Head and Neck Cancer|Neuroendocrine Tumors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Empirical Rescue Therapies of Helicobacter Pylori Infection
Status: COMPLETED
Conditions: Functional Dyspepsia|Scarred Peptic Ulcer
Interventions: DRUG: Proton Pump Inhibitor|DRUG: Bismuth|DRUG: Metronidazole|DRUG: Tetracycline|DRUG: Furazolidone|DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Duloxetine Potentiates the Analgesic Efficacy of Intrathecal Morphine
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Duloxetine 60mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Low Doses of Prednisone on the Prolongation of Pregnancy in Threatened Preterm Birth
Status: NOT_YET_RECRUITING
Conditions: Preterm Birth
Interventions: DRUG: Prednisone 5Mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Fentanyl Delivered by Adhesive Skin Patch in Out-Patients With Chronic Cancer Pain
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Microarchitecture Evaluation by HR-pQCT in Youngs Who Developed AN in Peri or Prepubertal Period.
Status: COMPLETED
Conditions: Anorexia Nervosa
Interventions: DEVICE: HR-pQCT|DEVICE: DEXA|OTHER: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Alvocidib, Fludarabine Phosphate, and Rituximab in Treating Patients With Lymphoproliferative Disorders or Mantle Cell Lymphoma
Status: COMPLETED
Conditions: B-cell Chronic Lymphocytic Leukemia|Contiguous Stage II Grade 1 Follicular Lymphoma|Contiguous Stage II Grade 2 Follicular Lymphoma|Contiguous Stage II Mantle Cell Lymphoma|Contiguous Stage II Marginal Zone Lymphoma|Contiguous Stage II Small Lymphocytic Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Nodal Marginal Zone B-cell Lymphoma|Noncontiguous Stage II Grade 1 Follicular Lymphoma|Noncontiguous Stage II Grade 2 Follicular Lymphoma|Noncontiguous Stage II Mantle Cell Lymphoma|Noncontiguous Stage II Marginal Zone Lymphoma|Noncontiguous Stage II Small Lymphocytic Lymphoma|Progressive Hairy Cell Leukemia, Initial Treatment|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Hairy Cell Leukemia|Splenic Marginal Zone Lymphoma|Stage I Chronic Lymphocytic Leukemia|Stage I Grade 1 Follicular Lymphoma|Stage I Grade 2 Follicular Lymphoma|Stage I Mantle Cell Lymphoma|Stage I Marginal Zone Lymphoma|Stage I Small Lymphocytic Lymphoma|Stage II Chronic Lymphocytic Leukemia|Stage III Chronic Lymphocytic Leukemia|Stage III Grade 1 Follicular Lymphoma|Stage III Grade 2 Follicular Lymphoma|Stage III Mantle Cell Lymphoma|Stage III Marginal Zone Lymphoma|Stage III Small Lymphocytic Lymphoma|Stage IV Chronic Lymphocytic Leukemia|Stage IV Grade 1 Follicular Lymphoma|Stage IV Grade 2 Follicular Lymphoma|Stage IV Mantle Cell Lymphoma|Stage IV Marginal Zone Lymphoma|Stage IV Small Lymphocytic Lymphoma|Untreated Hairy Cell Leukemia|Waldenström Macroglobulinemia
Interventions: DRUG: alvocidib|DRUG: fludarabine phosphate|BIOLOGICAL: rituximab|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexmedetomidine Versus Midazolam Versus a Combination of the Two as a Premedication for Children Undergoing Bilateral Myringotomy Tube Insertion
Status: WITHDRAWN
Conditions: Pre Operative Sedation|Mask Acceptance|Post Operative Delerium
Interventions: DRUG: Combination of Dexmedetomidine with Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Imexon Plus Gemcitabine in Untreated Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: imexon|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Contrast-induced Nephropathy in Patients With Acute Myocardial Infarction
Status: COMPLETED
Conditions: Contrast Induced Nephropathy
Interventions: OTHER: Hydration|DRUG: Acetylcysteine|DRUG: Sodium bicarbonate|DRUG: Combined Acetylcystein and Sodium Bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Quadratus Lumborum Block vs Erector Spinal Block for Post Abdomen Surgery Analgesia
Status: RECRUITING
Conditions: Pain, Acute|Postoperative Pain|Anesthetics, Local
Interventions: DRUG: Ropivacaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extensive Small Cell Lung Cancer Treatment Using An Investigational Drug Plus Chemotherapy In Chemotherapy-Naive Adults
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: topotecan/cisplatin|DRUG: etoposide/cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Four Popular Diet Strategies for Weight Loss and Cardiac Risk Reduction
Status: COMPLETED
Conditions: Obesity|Cardiovascular Disease|Metabolic Syndrome
Interventions: BEHAVIORAL: Atkins Diet|BEHAVIORAL: Zone Diet|BEHAVIORAL: Weight Watchers Diet|BEHAVIORAL: Ornish Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Laryngeal Mask and I-gel to Laryngoscope by Novice Operators in Simulated Difficult Airway
Status: UNKNOWN
Conditions: Airway Obstruction
Interventions: DEVICE: proceal laryngeal mask airway|DEVICE: tracheal tube|DEVICE: i-gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Frequency Modulated Neural Stimulation (FREMS) in Symptomatic Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathy, Painful
Interventions: DEVICE: Frequency Modulated Neural Stimulation (FREMS) (Aptiva)|DEVICE: sham treatment (Aptiva)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Flow Magnitude on Cardiorespiratory Stability During Nasal High Flow Therapy in Preterm Infants
Status: RECRUITING
Conditions: Respiratory Distress Syndrome
Interventions: OTHER: NHF high|OTHER: NHF low|OTHER: NCPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Micro-osteoperforations on the Rate of Canine Retraction
Status: COMPLETED
Conditions: Malocclusion
Interventions: OTHER: Micro-osteoperforations (MOPs)|OTHER: Conventional canine retraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single-Blind Study of STAT-205 in Mild COVID-19
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: STAT-205
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Allogenic CD19-CAR-NK Cells in Treatmenting r/r B-cell Hematologic Malignancies
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|B-cell Lymphoma|Chronic Lymphocytic Leukemia
Interventions: OTHER: allogenic CD19-CAR-NK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Tazarotene in Treatment of Verruca Plana
Status: UNKNOWN
Conditions: Warts Flat
Interventions: DRUG: Tazarotene 0.1% Gel,Top|DRUG: Imiquimod|DRUG: Fluorouracil Cream|DRUG: Petrolatum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Activated Recombinant Human Factor VII in Cardiac Surgery
Status: TERMINATED
Conditions: Acquired Bleeding Disorder|Cardiac Surgery Requiring Cardiopulmonary Bypass
Interventions: DRUG: activated recombinant human factor VII
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ET-743 (Trabectedin) in Patients With Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Neoplasms|Neoplasms by Site|Breast Diseases|Skin Diseases
Interventions: DRUG: ET743|DRUG: ET743
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Reduction of Inapparent Myocardial Injury
Status: COMPLETED
Conditions: Perioperative Myocardial Injury
Interventions: PROCEDURE: Remote ischaemic preconditioning|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Distribution and Prognostic Impact of Oncogenic Drivers in Metastatic Lung Adenocarcinoma : a Retrospective Monocentric Study in Nancy University Hospital Center
Status: COMPLETED
Conditions: Adenocarcinoma of Lung Stage IV|Adenocarcinoma of Lung, Response to Tyrosine Kinase Inhibitor in, Somatic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate Drug-Drug Interaction of TAK-788 With Itraconazole and Rifampin in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-788|DRUG: Itraconazole|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Proteomic Analysis of HLA Complex in Solid Cancers: Breast, Ovary, Colon, Rectum, Stomach, and Pancreas
Status: UNKNOWN
Conditions: Colorectal Neoplasms|Stomach Neoplasms|Pancreatic Neoplasms|Breast Neoplasms|Ovarian Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1 Study to Investigate Axatilimab Alone or in Combination With Durvalumab in Patients With Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor|Metastatic Tumor|Locally Advanced Malignant Neoplasm|Unresectable Malignant Neoplasm
Interventions: DRUG: Axatilimab|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT