pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Inguinal Lymphadenectomy for Penile Cancer
Status: COMPLETED
Conditions: Penile Cancer|Lymph Node Metastasis|Sentinel Lymph Node|Surgical Complication
Interventions: PROCEDURE: Inguinal Lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of Recombinant Human Rabies Immunoglobin (rhRIG) in Combination With Rabies Vaccine for Human Use With Human Rabies Immune Globulin (HRIG) in Combination With Rabies Vaccine for Human Use in Healthy Adult Subjects.
Status: COMPLETED
Conditions: Rabies
Interventions: BIOLOGICAL: rhRIG（20 IU/kg）|BIOLOGICAL: rhRIG（40 IU/kg）|BIOLOGICAL: HRIG（20 IU/kg）|BIOLOGICAL: rhRIG（20 IU/kg） and vaccine|BIOLOGICAL: rhRIG（40 IU/kg） and vaccine|BIOLOGICAL: HRIG（20 IU/kg） and vaccine|BIOLOGICAL: placebo and vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Oral Amantadine, IV Amantadine and Hemodynamic Response to Laryngoscopy
Status: UNKNOWN
Conditions: Intubation, Intratracheal
Interventions: DRUG: oral Amantadine sulfate|DRUG: i.v Amantadine Sulfate|DRUG: placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Immunogenicity of Norovirus GI.1/GII.4 Bivalent Virus-like Particle Vaccine in Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: NoV Placebo-matching Saline|BIOLOGICAL: NoV GI.1/GII.4 Bivalent VLP Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Various Types of Ultrasound Therapy in Hip Osteoarthritis
Status: UNKNOWN
Conditions: Hip Osteoarthritis
Interventions: DEVICE: Continuous ultrasound therapy|DEVICE: pulsed ultrasound therapy|DEVICE: US and electrotherapy (sonotens)|DEVICE: Sham ultrasound therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IBI310 in Combination With Siltilimab in Subjects With Anti-PD-1/PD-L1 Resistance R/M NPC
Status: COMPLETED
Conditions: NPC
Interventions: DRUG: Sintilimab|DRUG: IBI310
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient-centered Treatment of Anxiety After Low-Risk Chest Pain in the Emergency Room
Status: ACTIVE_NOT_RECRUITING
Conditions: Generalized Anxiety Disorder|Chest Pain|Panic
Interventions: BEHAVIORAL: Primary care follow-up|BEHAVIORAL: Online Self-Administered Anxiety Management Program plus Peer Support Guidance|BEHAVIORAL: Therapist-Administered Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Adverse Events and How Oral ABBV-990 Moves Through the Body of Adult Healthy Participants
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: ABBV-990|DRUG: Placebo for ABBV-990
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Continuous Adductor Canal Block for Total Knee Arthroplasty Analgesia
Status: UNKNOWN
Conditions: Neuromuscular Blockade|Pain Management
Interventions: PROCEDURE: Continuous femoral nerve block|PROCEDURE: Continuous adductor canal block|PROCEDURE: infragluteal Sciatic nerve block|DRUG: Ropivacaine 0.2%|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Preliminary Efficacy of sFilm-FS in Controlling Parenchymal Bleeding During Elective Hepatic Surgery
Status: COMPLETED
Conditions: Hemostasis|General Surgery
Interventions: COMBINATION_PRODUCT: sFilm-FS|COMBINATION_PRODUCT: TACHOSIL®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study of SC-43 in Combination With Cisplatin
Status: UNKNOWN
Conditions: Advanced Non-small-cell Lung Cancer|Advanced Biliary Tract Cancer
Interventions: DRUG: SC-43|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Absolute Bioavailability and ADME Study of Savolitinib in Healthy Male Subjects
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: AZD6094 (Savolitinib) film coated tablets 600 mg|DRUG: [14C]-AZD6094 (Savolitinib) Solution for Infusion, 20 μg/mL (NMT 37.0 kBq/5 mL)|DRUG: [14C] AZD6094 (Savolitinib) Oral Solution, 300 mg (NMT 4.1 MBq)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Absolute BA and OZ439 PK Effect of Different OZ439 Dose Volumes and Cobicistat Co-administration Study
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Single oral dose of 800 mg OZ439|DRUG: Single oral dose of 400 mg OZ439|DRUG: Single oral dose of cobicistat|DRUG: iv infusion of [14C]-OZ439
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BRENTUXIMAB VEDOTIN as Pre-ASCT Induction Therapy in R/R HL Patients Non Responding to IGEV
Status: COMPLETED
Conditions: Relapsed/Refractory Hodgkin's Lymphoma
Interventions: DRUG: BRENTUXIMAB VEDOTIN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Advanced Hodgkin's Disease
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: bleomycin sulfate|DRUG: ABVD regimen|DRUG: chlorambucil|DRUG: dacarbazine|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: prednisolone|DRUG: procarbazine hydrochloride|DRUG: vinblastine sulfate|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Pharmacokinetics (PK) of Single Subcutaneous (SC) Injections of Vedolizumab Administered in Prefilled Syringe (PFS) Versus (vs) Prefilled Syringe in Needle Safety Device (PFS+NSD) in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Vedolizumab SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PF-04191834 Single Dose Bronchodilatory Study In Asthma.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: PF-04191834|DRUG: PF-04191834|DRUG: PF-04191834|DRUG: zileuton|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lock sOlutiOnS for Epicutaneo-caval Catheters in Neonates: a "LOOSEN" Pilot Study
Status: RECRUITING
Conditions: Catheter-related Bloodstream Infection|Preterm|Catheter Infection|Catheter Complications
Interventions: COMBINATION_PRODUCT: neutrox
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ischemic Injury and Ischemic Preconditioning in Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Insulin-Dependent|Ischemia-Reperfusion Injury
Interventions: PROCEDURE: Ischemic preconditioning|PROCEDURE: Forearm ischemic exercise|PROCEDURE: Annexin A5 scintigraphy|DRUG: Diazoxide|DRUG: glibenclamide|DRUG: adenosine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Plyometric and Resistance Warmup on Running Performance in Athlets
Status: COMPLETED
Conditions: Sports Physical Therapy
Interventions: OTHER: plyometric warm up group|OTHER: resistance warm up|OTHER: control warm up group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Tirzepatide (LY3298176) in Pediatric and Adolescent Participants With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin or Basal Insulin or Both
Status: ACTIVE_NOT_RECRUITING
Conditions: Type2 Diabetes|Diabetes Mellitus|Diabetes Mellitus, Type 2|T2D|T2DM (Type 2 Diabetes Mellitus)|Glucose Metabolism Disorders|Endocrine System Diseases|Metabolic Disease
Interventions: DRUG: Tirzepatide Dose 1|DRUG: Tirzepatide Dose 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Interventions and Metabolic Profile in Obese Children
Status: COMPLETED
Conditions: Childhood Obesity|Obesity|Pediatric Obesity|Dyslipidemias|Cardiovascular Risk Factor|Life Style
Interventions: BEHAVIORAL: Normocaloric and balanced diet, physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Angiotensin Therapeutic Vaccine in Subjects With Mild to Moderate Hypertension
Status: TERMINATED
Conditions: Hypertension|Cardiovascular Disease
Interventions: BIOLOGICAL: Angiotensin Therapeutic Vaccine plus CoVaccine HT™ adjuvant|BIOLOGICAL: CoVaccine HT™ adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-articular Oxygen-ozone Therapy for the Treatment of Knee Osteoarthritis Compared With Hyaluronic Acid
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DRUG: Ozone|DRUG: Hyaluronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a 24 Hour Phone Line on the Rate of Suicide Attempts in Borderline Patients
Status: COMPLETED
Conditions: Borderline Personality Disorder
Interventions: OTHER: 24 hour phone line|OTHER: treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Left Ventricular Functional Changes of Uncontrolled Diabetes by Dapagliflozin Treatment Trial
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Diabetes Medicines|DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation (TMS) to Treat mTBI and PTSD
Status: UNKNOWN
Conditions: Traumatic Brain Injury|Post-Traumatic Stress Disorder
Interventions: DEVICE: Transcranial Magnetic Stimulation|DEVICE: Sham Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High Dose Oral 4-Aminosalicylic Acid (PASER®) to Control Acute Flares of Mild to Moderate Crohn's Disease in Children
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DRUG: 4-Aminosalicylic acid extended release granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correction of Vitamin D Deficiency and Its Effect on Ovulation Induction in Women With PCOS (VIDEO): A Feasibility RCT
Status: COMPLETED
Conditions: PCOS
Interventions: DRUG: Vitamin D|DRUG: Ovulatory Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep Apnea Syndrome on Acromegaly: Impact of the Treatment on the Carbohydrates Metabolism.
Status: UNKNOWN
Conditions: Acromegaly|Obstructive Sleep Apnea|Insulin Resistance
Interventions: DEVICE: Continuous positive air pressure device (CPAP)|OTHER: External nasal dilator adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using Navigation to Improve Accuracy of Maxillary Balloon Sinusotomy
Status: NOT_YET_RECRUITING
Conditions: Chronic Maxillary Rhinosinusitis
Interventions: DEVICE: RELIEVA SPINPLUS® NAV Balloon Sinusplasty System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Studying Biomarkers in Samples From Younger Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Childhood Acute Monoblastic Leukemia (M5a)|Childhood Acute Monocytic Leukemia (M5b)|Childhood Acute Myeloblastic Leukemia Without Maturation (M1)|Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies|Childhood Acute Myelomonocytic Leukemia (M4)
Interventions: OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of the St. Jude Medical PorticoTM Re-sheathable Aortic Valve System - Alternative Access
Status: WITHDRAWN
Conditions: Symptomatic Aortic Stenosis
Interventions: DEVICE: Portico Transcatheter Aortic Valve
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavior Change Intervention for Cardiovascular Risk Reduction Among People Experiencing Homelessness
Status: RECRUITING
Conditions: Heart Diseases|Diabetes Mellitus, Type 2|Pre-diabetes|Hypertension|Hyperlipidemias
Interventions: BEHAVIORAL: Cardiovascular Risk Homeless Support
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Inflammation and Pain Post Injection of Ranibizumab vs Aflibercept in Patients With DME
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Ranibizumab 0.3 mg|DRUG: Aflibercept 2.0 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease|Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder)|Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 2 (Disorder)|Autosomal Dominant Alzheimer Disease Due to Mutation of Amyloid Precursor Protein (Disorder)
Interventions: DRUG: NIO752|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antenatal Dexamethasone for Late Preterm Deliveries
Status: RECRUITING
Conditions: Respiratory Distress of Newborn|Preterm Birth
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability of Antiplaque Chewing Gum in a Gingivitis Population
Status: COMPLETED
Conditions: Plaque|Gingivitis
Interventions: DRUG: 2 mg KSL-W|DRUG: 4 mg KSL-W|DRUG: 6 mg KSL-W|DRUG: 10 mg KSL-W|DRUG: 20 mg KSL-W|DRUG: 30 mg KSL-W|DRUG: 50 mg KSL-W|DRUG: 75 mg KSL-W|DRUG: 100 mg KSL-W|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: WISE CVD - Continuation (WISE HFpEF)
Status: RECRUITING
Conditions: Microvascular Coronary Dysfunction|Cardiovascular Disease
Interventions: PROCEDURE: Coronary Angiography|PROCEDURE: Coronary Reactivity Testing|PROCEDURE: Cardiac Magnetic Resonance Imaging|PROCEDURE: Cardiac Magnetic Resonance Angiography|PROCEDURE: Computed Coronary Tomographic Angiography|PROCEDURE: Rest-Stress Millar Testing|PROCEDURE: Aortic vasorelaxation tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Novel MRI for Diagnosing Traumatic Brachial Plexus Injuries
Status: UNKNOWN
Conditions: Brain Injuries
Interventions: DIAGNOSTIC_TEST: Novel MRI scan - 7 days post injury|DIAGNOSTIC_TEST: Novel MRI scan - 14 days post injury|DIAGNOSTIC_TEST: Functional MRI scan - 6 months post brachial plexus exploration|DIAGNOSTIC_TEST: Functional MRI scan - 12 months post brachial plexus exploration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BMS-247550 in Treating Patients With Advanced Cancers
Status: COMPLETED
Conditions: Lymphoma|Small Intestine Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electroconvulsive Therapy (ECT) in Patients With Super Refractory Schizophrenia
Status: UNKNOWN
Conditions: Refractory Schizophrenia|Super Refractory Schizophrenia
Interventions: DEVICE: MECTA SPECTRUM 5000Q ECT|PROCEDURE: Sham ECT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Red Light in the Treatment of Pigmentary Disorders
Status: UNKNOWN
Conditions: Melasma|Lichen Planus Pigmentosus|Vitiligo
Interventions: DEVICE: Red light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Botulinum Toxin and ESWT Applications on Spasticity and Functionality in Cerebral Palsy Patients
Status: RECRUITING
Conditions: Cerebral Palsy, Spastic
Interventions: DEVICE: Extracorporeal Shock Wave Therapy|DRUG: Botilinum Toxin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurophysiological Effects of tPCS and tDCS on Patients With Disorders of Consciousness
Status: COMPLETED
Conditions: Disorders of Consciousness
Interventions: DEVICE: Active tPCS|DEVICE: Active tDCS|DEVICE: Sham tPCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing OTC Acne Treatment to Prescription Regimen
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: BenzaClin|DRUG: Effaclar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Analysis of Ultrasound-guided Intratissue Percutaneous Electrolysis (EPI) in Patient With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: OTHER: Ultrasound-guided percutaneous electrolysis in the lumbar nerve root|OTHER: Electrical Dry Needling in trigger points
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Onset and Duration of Action of AKF-1 Ophthalmic Solution in Treating Acute Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: AKF-1|DRUG: AKF-1|DRUG: AKF-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomised Evaluation of Sodium Dialysate Levels on Vascular Events
Status: RECRUITING
Conditions: End-Stage Kidney Disease
Interventions: OTHER: Default dialysate sodium concentration of 137mmol/l|OTHER: Default dialysate sodium concentration of 140mmol/l
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Humeral or Thoracic Implantation of an Central Veinous Access by an Implantable Venous Access Device in Patients With Solid Tumors Requiring Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor, Adult|Chemotherapy Treatment|Advanced or Metastasis Stage
Interventions: DEVICE: IPolysite ® Mini série 3108 or Polysite ® Standard, série 4108.|DEVICE: Vital Port®Minititanium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Platform Study of Novel Ruxolitinib Combinations in Myelofibrosis Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelofibrosis
Interventions: DRUG: Ruxolitinib|DRUG: Siremadlin|DRUG: Crizanlizumab|DRUG: Sabatolimab|DRUG: Rineterkib|DRUG: NIS793
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Confocal Laser Endomicroscopy for the Detection of Gastric Intestinal Metaplasia: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Intestinal Metaplasia
Interventions: DEVICE: Endomicroscope|DEVICE: Standard endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Relative Bioavailability Study of PF-07321332/Ritonavir Oral Powder Relative to the Commercial Tablets in Healthy Participants
Status: COMPLETED
Conditions: Bioavailability
Interventions: DRUG: PF-07321332/ritonavir|DRUG: PF-07321332/ritonavir|DRUG: PF-07321332/ritonavir|DRUG: PF-07321332/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Oral Encochleated Amphotericin B for the Treatment of Cryptococcal Infection
Status: WITHDRAWN
Conditions: Cryptococcal Infections
Interventions: DRUG: Encochleated Amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Therapeutic Potential of the FDA-approved Drug Metformin for C9orf72 ALS/FTD
Status: ACTIVE_NOT_RECRUITING
Conditions: C9orf72 Amyotrophic Lateral Sclerosis (ALS)|Frontotemporal Dementia
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing a Novel Dry Electrode Headset for Electroencephalography Telehealth
Status: ENROLLING_BY_INVITATION
Conditions: Epilepsy
Interventions: DEVICE: standard EEG|DEVICE: dry electrode EEG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Acupuncture in the Treatment of Infant Colic
Status: COMPLETED
Conditions: Infant Colic
Interventions: PROCEDURE: Acupuncture with Seirin 020x15 mm sterile acupuncture needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The ADVISE Study: Advanced Visualization In Corneal Surgery Evaluation
Status: COMPLETED
Conditions: Fuchs Dystrophy|Endothelial Corneal Dystrophy|Bullous Keratopathy|Vision Disorders
Interventions: DEVICE: intraoperative optical coherence tomography (iOCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: TACE in Combination With PD-1/PD-L1 Inhibitors and Molecular Target Therapies for Advanced HCC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: PD-1/PD-L1 inhibitors+VEGF-TKI/bevacizumab|PROCEDURE: TACE
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Determine the Pharmacokinetics of Cediranib in Chinese Patients With Advanced Solid Malignancies
Status: COMPLETED
Conditions: Advanced Solid Malignancies
Interventions: DRUG: cediranib (RECENTIN TM, AZD2171)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Administration of Growth Hormone to Increase CD4+ Count in Patients Taking Anti-HIV Drugs
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: somatropin|BIOLOGICAL: Hepatitis A virus, inactivated|DRUG: Keyhole-Limpet Hemocyanin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Oral Acetazolamide, Brimonidine Tartarate, and Anterior Chamber Paracentesis in Intraocular Pressure (IOP) After Bevacizumab
Status: COMPLETED
Conditions: Macular Edema|Diabetic Retinopathy|Macular Degeneration
Interventions: DRUG: bevacizumab|PROCEDURE: anterior chamber paracentesis|DRUG: acetazolamide|DRUG: brimonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Pain Neuroscience Education in Chronic Musculoskeletal Pain
Status: COMPLETED
Conditions: Chronic Musculoskeletal Pain
Interventions: BEHAVIORAL: PNE+Physiotherapy|PROCEDURE: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gastric Residual Volumes in Infants Fed at 4 and 6 Hours Prior to General Anaesthesia
Status: NOT_YET_RECRUITING
Conditions: Fasting|Anesthesia|Pediatric ALL
Interventions: OTHER: abdominal ultrasound, insertion of naso-gastric tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nivolumab + Ipilimumab With Immunostimulatory Embolization for Stage 4 Renal Cell Carcinoma With Unresected Primary
Status: TERMINATED
Conditions: Renal Cell Carcinoma|Renal Cell Carcinoma Stage IV
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|DEVICE: bland embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Anti-inflammatory Effects of Topical R115866 Gel
Status: COMPLETED
Conditions: Cutaneous Inflammation
Interventions: DRUG: Talarozole|DRUG: Differin™, 0.1% adapalene gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Thoracic Paravertebral Block : Effect on Acute Pain and Chronic Pain of Hepatectomy With Right J-shape Subcostal Incision
Status: COMPLETED
Conditions: Hepatectomy|Analgesia|Nerve Block
Interventions: PROCEDURE: single-injection TPVB + continuous TPVB|DEVICE: Philip CX50 Ultrasound Scanner|DEVICE: PAJUNK Contiplex S Catheter|DRUG: single dose ropivacaine|DRUG: continuously infusion of ropivacaine|DRUG: Morphine given as IPCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chronotropic Incompetence During Exercise in Obese Adolescents: Clinical Implications and Pathophysiology
Status: COMPLETED
Conditions: Obesity|Adolescent Obesity
Interventions: OTHER: the prevalence of chronotropic incompetence CI during maximal cardiopulmonary exercise testing, CPET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: AZ, MZ, and the Pulmonary System Response to Hypoxia
Status: COMPLETED
Conditions: Altitude Sickness|Hypertension, Pulmonary
Interventions: DRUG: Acetazolamide|DRUG: Methazolamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect and Long-Term Outcomes of Indocyanine Green Fluorescence Imaging Method Versus Modified Inflation-Deflation Method in Identification of Intersegmental Plane（IMPLANE-0529）
Status: RECRUITING
Conditions: Segmentectomy|Non-small Cell Lung Cancer Stage I
Interventions: PROCEDURE: Indocyanine green fluorescence imaging method|PROCEDURE: Modified inflation-deflation method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRotEin Provision in Critical IllneSs
Status: COMPLETED
Conditions: Critical Illness|Intensive Care Unit Acquired Weakness
Interventions: DIETARY_SUPPLEMENT: PRECISe protocol EN 8g protein/100kcal|DIETARY_SUPPLEMENT: PRECISe protocol EN 5g protein/100kcal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examining the Efficacy of Mattress Technology in Improving the Sleep Quality of Children With ASD
Status: COMPLETED
Conditions: Autism Spectrum Disorders
Interventions: DEVICE: Sound to Sleep System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized Trial of a Mobile Health Exercise Intervention for Older Adults With Myeloid Neoplasms
Status: RECRUITING
Conditions: Cancer|Myeloid Neoplasm
Interventions: BEHAVIORAL: GO-EXCAP Mobile App|BEHAVIORAL: Behavioral Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: IMM60 and Pembrolizumab in Melanoma and NSCLC
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer|Melanoma
Interventions: DRUG: IMM60|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagosis of Breast Carcinoma: Characterization of Breast Lesions With CLEARPEMSONIC : Feasibility Study
Status: TERMINATED
Conditions: Breast Carcinoma
Interventions: DEVICE: MRI|DEVICE: PET-CT scan|DEVICE: PEM scan with ClearPemSonic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Positron Emission Tomography and Computed Tomography in Planning Treatment for Patients Undergoing 3-Dimensional Conformal Radiation Therapy for Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery. ICORG 06-35
Status: TERMINATED
Conditions: Lung Cancer|Metastatic Cancer
Interventions: PROCEDURE: computed tomography|RADIATION: 3-dimensional conformal radiation therapy|RADIATION: fludeoxyglucose F 18|RADIATION: radiation therapy treatment planning/simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Two Oral Tinidazole Regimens for Refractory Trichomonas Vaginitis
Status: NOT_YET_RECRUITING
Conditions: Trichomonas Vaginitis
Interventions: DRUG: Tinidazole 56|DRUG: Tinidazole 42
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of DA-5515 (Circulan® Soft Cap.) in Patients With Chronic Fatigue Symptoms Due to Impaired Blood Circulation
Status: UNKNOWN
Conditions: Fatigue Symptom
Interventions: DRUG: DA-5515|DRUG: Placebo of DA-5515
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Psychotropic Medications Among Pregnant Women With Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder|Pregnancy Complications
Interventions: DRUG: Antipsychotic|DRUG: Antidepressant|DRUG: Antipsychotic and Antidepressant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A RCT to Compare the Effects of Two Wound Products on Biofilm Disruption in DFUs
Status: TERMINATED
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: Iodosorb|DEVICE: Solosite gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Prophylactic Emicizumab Versus no Prophylaxis in Hemophilia A Participants With Inhibitors
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: Emicizumab|DRUG: rFVIIa|DRUG: aPCC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Persistent Opioid Use in Mothers
Status: COMPLETED
Conditions: Opioid Use|Postpartum Disorder|Chronic Pain Syndrome
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Osteopathic Single CAse Research for Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: OTHER: Osteopathic Manual Treatment|OTHER: Self-management|OTHER: Reassurance|OTHER: Biopsychosocial management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Assess the Safety, Tolerability and Efficacy of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension
Status: COMPLETED
Conditions: Chronic Thromboembolic Pulmonary Hypertension
Interventions: DRUG: Macitentan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2181308 Sodium in Patients With Relapsed or Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: LY2181308 sodium|DRUG: cytarabine|DRUG: idarubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: External Oblique Intercostal Plane Block vs. Wound Infiltration for Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: ultrasound guided external oblique intercostal plane block|OTHER: Wound infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dietary Supplement for Early Cigarette Withdrawal
Status: COMPLETED
Conditions: Nicotine Dependence, Cigarettes, With Withdrawal
Interventions: DRUG: Dietary Supplement|DRUG: Lactose Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Novel Health Information Technology System (BMT Roadmap) for Pediatric BMT Patients and Caregivers
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Brain Tumor
Interventions: BEHAVIORAL: Education information system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preemptive Analgesia Using Intravenous Paracetamol
Status: COMPLETED
Conditions: Adverse Anesthesia Outcome
Interventions: DRUG: Paracetamol|DRUG: Paracetamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial of Chemotherapy Plus Intravenous Vitamin C in Patients With Advanced Cancer for Whom Chemotherapy Alone is Only Marginally Effective
Status: COMPLETED
Conditions: Cancer
Interventions: DIETARY_SUPPLEMENT: vitamin C (ascorbic acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Hyaluronic-acid and Hydrogen-Peroxide Mouthwash in Gingivitis Treatment
Status: UNKNOWN
Conditions: Gingivitis|Bleeding Gum
Interventions: DRUG: Filming mouthwash formulation, enriched with Hydrogen Peroxide and Hyaluronic Acid|DRUG: Chlorhexidine mouthwash|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CCTA, CACS and ECG Stress Testing in Patients With Suspected CAD: Precision Phenotyping and Financial Evaluation
Status: UNKNOWN
Conditions: Stable Angina|Coronary Artery Disease|Atherosclerosis|Coronary Artery Calcification
Interventions: DIAGNOSTIC_TEST: CCTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pharmacokinetic and Safety Study of IV Gallium Nitrate (Ganite) in Cystic Fibrosis Patients
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: 100 mg/m2 dose|DRUG: 200 mg/m2 dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Viscosity of Fibre Predicts Cholesterol-lowering in Healthy Individuals
Status: COMPLETED
Conditions: Lipidemia|Healthy
Interventions: DIETARY_SUPPLEMENT: Viscous Fibre Blend|DIETARY_SUPPLEMENT: Psyllium|DIETARY_SUPPLEMENT: Wheat Bran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Determining the Impact of a Physiotherapist-led Primary Care Model for Hip and Knee Pain - A Cluster Trial
Status: RECRUITING
Conditions: Hip Osteoarthritis|Knee Osteoarthritis
Interventions: OTHER: Physiotherapist-led primary care model for hip and knee pain|OTHER: Usual physician-led primary care model for hip and knee pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation in Pediatric Patients
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases (IBD)|Crohn's Disease (CD)|Ulcerative Colitis (UC)
Interventions: BIOLOGICAL: Fecal Microbiota Transplantation (FMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incisional Vacuum Assisted Closure (IVAC) Device and Its Effect on Implanted Bone Morphogenic Protein (BMP-2)
Status: COMPLETED
Conditions: Fractures, Closed
Interventions: OTHER: 75 mmHg suction|OTHER: 125 mmHg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Behavioral and Psychological Symptoms of Dementia: Hospital Caregivers (Aim 2)
Status: COMPLETED
Conditions: Alzheimer's Disease and Related Dementias
Interventions: BEHAVIORAL: PES-4-BPSD Model|BEHAVIORAL: The attention control condition
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Video Education and Behaviour Contract to Optimize Adherence in Renal Transplants
Status: COMPLETED
Conditions: Kidney Transplantation|Medication Adherence
Interventions: BEHAVIORAL: Video education + adherence contract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SRAE With Embospheres for Hemorrhoids.
Status: UNKNOWN
Conditions: Embolization|Hemorrhoids
Interventions: DEVICE: Embolization with tri-acryl gelatin (Embosphere) particles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Parent Connectors in First Episode Psychosis (FEP)
Status: WITHDRAWN
Conditions: First Episode Psychosis (FEP)
Interventions: BEHAVIORAL: PPN|BEHAVIORAL: CSC Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Transdiagnostic Group Therapy (GBAT) for Autistic Adults With Personalized Therapeutics
Status: RECRUITING
Conditions: GBAT+Individual|GBAT+Engagement Booster|GBAT+Both
Interventions: OTHER: GBAT+I, GBAT+E - Phase I|OTHER: Watchful Waiting and Groups - Phase 2|OTHER: GBAT+IE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation on the Middle Size Molecule Elimination Characteristics of the FXCorDiax 100 in Relation to the FX 100 and the Polyflux 210 H Dialyser
Status: COMPLETED
Conditions: Renal Failure Chronic Requiring Hemodialysis
Interventions: DEVICE: 4 h online hemodiafiltration (FX 100, Polyflux 210, FXCorDiax)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omnitram Safety and Efficacy in the Treatment of Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathies|Neuropathic Pain|Pain, Chronic
Interventions: DRUG: Omnitram Oral Tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Healthy Volunteer Pharmacokinetics (PK)/Pharmacodynamics (PD), Safety and Tolerability Study of Andexanet in Healthy Japanese and Caucasian Subjects
Status: COMPLETED
Conditions: Bleeding
Interventions: BIOLOGICAL: Andexanet alfa|DRUG: Apixaban|DRUG: Rivaroxaban|DRUG: Edoxaban|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy With TG4040 in Treatment-naïve Patients Chronically Infected With Hepatitis C Virus
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: BIOLOGICAL: MVA-HCV (Immunotherapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Tandutinib in Patients With Newly Diagnosed Acute Myelogenous Leukemia Who Are Considered Ineligible For or Who Decline Treatment With Standard Induction Therapy
Status: WITHDRAWN
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: tandutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: DDR-Umbrella Study of DDR Targeting Agents in Advanced Biliary Tract Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Bile Duct Cancer|Chemotherapy Effect
Interventions: DRUG: AZD6738|DRUG: Durvalumab|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Evolocumab as an Additional Lipid-lowering Therapy to Changes in Lipid Core Burden Index of Non-culprit Vulnerable Plaque in Patients Who Underwent Percutaneous Coronary Intervention for the Acute Coronary Syndrome
Status: RECRUITING
Conditions: Clinical Trial|Acute Coronary Syndrome
Interventions: DRUG: Evolocumab|DEVICE: NIRS IVUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of a Novel Scheimpflug Device in Diagnosing Keratoconus
Status: ACTIVE_NOT_RECRUITING
Conditions: Scansys, Pentacam, Corvis ST, Keratoconus, Subclinical Keratoconus
Interventions: OTHER: Pentacam, Corvis ST and Scansys
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Inorganic Nitrate on Cardiac Muscle in Angina
Status: COMPLETED
Conditions: Chronic Stable Angina
Interventions: DRUG: Sodium Nitrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Sanofi Pasteur Pentaxim Combined Vaccine in Infants in Thailand
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Poliomyelitis|Haemophilus Infections|Pertussis
Interventions: BIOLOGICAL: Diphtheria, Tetanus, Polio, Acellular Pertussis and Hib Vac
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Measuring the Impact of an Enhanced Strategy for Daily Disinfection in Acute Care Hospital Rooms
Status: COMPLETED
Conditions: Disinfection
Interventions: OTHER: Sani24|OTHER: Routine Disinfection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Supplementation of Oral Reduced Glutathione in Pediatric Cystic Fibrosis Patients
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DIETARY_SUPPLEMENT: Oral reduced l-glutathione|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Toolbox Training on Radiation Protection Practices of Health Professionals in Radioactive Workplaces
Status: NOT_YET_RECRUITING
Conditions: Health Physics, Healthcare Professionals, Toolbox Trainings
Interventions: BEHAVIORAL: Toolbox trainings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION