pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Reflux Esophagitis Phase III Study (Maintenance Treatment)
Status: COMPLETED
Conditions: Reflux Esophagitis
Interventions: DRUG: Esomeprazole|DRUG: Esomeprazole|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lenticule Implantation and Autologous Serum New Approach in Treatment of Adenoviral Keratitis Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Adenoviral Keratoconjunctivitis
Interventions: OTHER: relex smile
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Pemigatinib (INCB054828) in Subjects With Urothelial Carcinoma - (FIGHT-201)
Status: COMPLETED
Conditions: UC (Urothelial Cancer)
Interventions: DRUG: pemigatinib|DRUG: pemigatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pacemaker Holter Assessment of the Effect of BMS-914392 on Atrial Fibrillation Burden
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: BMS-914392|DRUG: BMS-914392|DRUG: BMS-914392|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: POC Study of Pipamperone Added to Stable Treatment With RIS or PAL in Chronic Schizophrenia
Status: COMPLETED
Conditions: Chronic Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Pipamperone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of STYLAGE® M Lidocaïne for Lips' Volume Augmentation and/or Redefinition of the Outline of the Lips (SMILE)
Status: COMPLETED
Conditions: Esthetics
Interventions: DEVICE: STYLAGE M Lidocaine|DEVICE: Active control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Metformin on the Correlation Between Hyperinsulinemia and Hypertension
Status: COMPLETED
Conditions: Diabetes Mellitus|Essential Hypertension
Interventions: DRUG: Fosinopril|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Dissonance and Attentional Biases Related to Body Dissatisfaction
Status: COMPLETED
Conditions: Body-dissatisfaction
Interventions: OTHER: The Body Project|OTHER: Mediapsychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Use of Zoledronic Acid to Prevent Cancer-treatment Bone Loss in Post-menopausal Women Receiving Adjuvant Letrozole for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Zoledronic acid|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-operative Application of HEMOPATCH to the Pancreatic Stump to Prevent Post-operative Pancreatic Fistula Following Distal Pancreatectomy
Status: COMPLETED
Conditions: Pancreas Cancer|Pancreas Disease|Pancreas Adenocarcinoma|Pancreas; Fistula|Surgery|Surgery--Complications|Surgery Site Fistula
Interventions: DEVICE: Hemopatch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Lumbar Repositioning Feedback and Transversus Abdominis Training on Lumbar Propricption in Patients With Chronic Mechanical Low Back Pain
Status: UNKNOWN
Conditions: Orthopedic Disorder
Interventions: DEVICE: including sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prehospital Analgesia With Intra-Nasal Ketamine
Status: COMPLETED
Conditions: Pain|Acute Pain
Interventions: DRUG: Ketamine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Fluorescence With Augmented Reality
Status: COMPLETED
Conditions: Vascular; Lesion, Central Nervous System|Brain Tumor|Cerebral Aneurysm|Cerebral AVM
Interventions: DEVICE: GLOW800|DRUG: indocyanine green (ICG)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Oral Insulin to Reduce Liver Fat Content in Type 2 Diabetes Patients With Nonalcoholic Steatohepatitis (NASH)
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis (NASH)
Interventions: DRUG: ORMD-0801 QD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Add-on Therapy With DLBS3233 in Patients With Type-2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type-2 Diabetes Mellitus
Interventions: DRUG: DLBS3233
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Uterine Manipulator in Hysterectomy - Ro.Man.HY
Status: UNKNOWN
Conditions: Endometrial Cancer
Interventions: DEVICE: Clermont-Ferrand Uterine Manipulator|OTHER: No uterine Manipulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Strengthening Exercise on the Brain for Early Dementia and Normative Older Adults
Status: COMPLETED
Conditions: Cognitive Decline|Dementia|Alzheimer's Disease|Mild Cognitive Impairment
Interventions: BEHAVIORAL: Strengthening exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Confirmatory Clinical Trial of the Evera MRI System for Conditionally-safe MRI Access
Status: COMPLETED
Conditions: Implantable Defibrillator
Interventions: DEVICE: MRI scan sequences of the head and chest regions|OTHER: Waiting Period Visit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraluminal Peppermint Oil and Adenoma Detection Rate in Screening Colonoscopy
Status: COMPLETED
Conditions: Colonic Polyp
Interventions: DRUG: Intraluminal peppermint oil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Nocardia Rubra Cell Wall Skeleton in Combination With Prior Second- or Third-line Regimens for the Treatment of Potentially Hazardous Colorectal Cancer SD Status
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Colorectal Neoplasms
Interventions: DRUG: Nocardia Rubra Cell Wall Skeleton in Combination With Prior Second- or Third-line Regimens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Apatinib in Combination With Raltitrexed Treatment in Patients With Advanced Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: raltitrexed combined with apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison for the Effect of Neuromuscular Blocking Agents Versus Sedation Alone on Severe ARDS Patients Due to COVID-19
Status: UNKNOWN
Conditions: COVID-19 Acute Respiratory Distress Syndrome|Sedation Complication|ICU Acquired Weakness
Interventions: DRUG: muscle relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Trabectedin in Patients With Advanced Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasms|Endocrine Gland Neoplasms|Neoplasms by Site|Neoplasms|Ovarian Diseases|Adnexal Diseases|Genital Diseases, Female
Interventions: DRUG: Trabectedin|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Laserpuncture and Standard Antiemetic on RINVR Scores in Adolescent Patients Undergoing Chemotherapy
Status: COMPLETED
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DEVICE: laserpuncture|DEVICE: Sham Laserpuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemorrhoidectomy in Patients With Grade III and IV Disease:Harmonic Scalpel Compared With Conventional Technique
Status: COMPLETED
Conditions: Hemorrhoidectomy|Third Degree Hemorrhoids|Fourth Degree Hemorrhoids|Operative Time|Postoperative,Pain|Length of Stay
Interventions: PROCEDURE: Hemorrhoidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Delirium in Inpatients Utilizing Melatonin
Status: TERMINATED
Conditions: Delirium
Interventions: DRUG: Melatonin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: External Pharyngeal Exerciser for Dysphagia
Status: UNKNOWN
Conditions: Pharyngeal Dysphagia|Dysphagia|Oral Pharyngeal Dysphagia
Interventions: DEVICE: pharyngeal exerciser + standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing a Mobile Application for the Care of Children With Gastrostomy and The Effect of the Application on Gastrostomy
Status: NOT_YET_RECRUITING
Conditions: Neuromuscular Diseases|Gastrointestinal Diseases
Interventions: OTHER: Mobile Application Supported Education Program (G-MUEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability, and Immunogenicity of a 3-dose Regimen of V114 in Healthy Infants (PNEU-PED-EU-2/V114-026)
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: DRUG: V114|DRUG: Prevenar 13™|DRUG: Vaxelis™|DRUG: M-M-R®II|DRUG: VARIVAX™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine in Borderline Personality Disorder
Status: TERMINATED
Conditions: Borderline Personality Disorder
Interventions: DRUG: Ketamine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine to Prevent Recurrence in Patients With HER-2 Positive Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer Female|Breast Cancer, Male|Breast Cancer Stage I|Breast Cancer Stage II|Breast Cancer Stage III|Residual Disease|HER2-positive Breast Cancer|HER2 Positive Breast Carcinoma
Interventions: BIOLOGICAL: DC1 Vaccine|BIOLOGICAL: WOKVAC Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbon Dioxide Versus Iodine Contrast for Endovascular Revascularization of Aortoiliac Occlusive Disease
Status: COMPLETED
Conditions: Aortoiliac Occlusive Disease
Interventions: PROCEDURE: Aortoiliac angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pediatric Fast Fluid Trial 2
Status: COMPLETED
Conditions: Resuscitation|Shock|Fluid Therapy|Pediatrics
Interventions: PROCEDURE: Push-Pull technique|PROCEDURE: Disconnect-Reconnect Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Correlation Between IMR（Index of Microcirculation Resistance） and FFR（Fractional Flow Reserve）
Status: UNKNOWN
Conditions: Myocardial Ischemia
Interventions: COMBINATION_PRODUCT: FFR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Compare the Safety and Efficacy of UB-851 and Eprex®
Status: COMPLETED
Conditions: Renal Anemia
Interventions: BIOLOGICAL: UB-851|BIOLOGICAL: Eprex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Opiate Dependence: Combined Naltrexone/Behavior Therapy - 1
Status: COMPLETED
Conditions: Heroin Dependence
Interventions: DRUG: Naltrexone|BEHAVIORAL: Behavioral Naltrexone Therapy (BNT)|BEHAVIORAL: Compliance Enhancement (CE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Allogenic Platelet Lysate in Peripheral Arterial Disease (PAD)
Status: UNKNOWN
Conditions: Peripheral Arterial Disease
Interventions: BIOLOGICAL: Platelet lysate|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Breast Conserving Surgery With Intra-operative Navigation System
Status: RECRUITING
Conditions: Breast-Conserving Surgery|Negative Surgical Margins|Endoscopy|Esthetics
Interventions: DEVICE: Intra-operative Navigation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Evaluation of TRC105 In Combination With Bevacizumab in Patients With Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma|Glioblastoma Multiforme
Interventions: DRUG: TRC105|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The COllaborative Neonatal Network for the First CPAM Trial
Status: RECRUITING
Conditions: Congenital Pulmonary Airway Malformation
Interventions: PROCEDURE: Elective surgical resection of CPAM between 6 and 9 months of age
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of T Cells Targeting CD138/BCMA/CD19/More Antigens (CART-138/BCMA/19/More) for Chemotherapy Refractory and Relapsed Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: CART-138/BCMA/19/more
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy and Safety of Intra-peritoneal Infusion of Catumaxomab and Treatment of Investigator Choice in Patients With Advanced Gastric Carcinoma With Peritoneal Metastasis
Status: RECRUITING
Conditions: Stomach Neoplasms
Interventions: DRUG: Catumaxomab|DRUG: The treatment of investigator choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radicle GI Health: A Study of Health and Wellness Products on GI Health and Other Health Outcomes
Status: COMPLETED
Conditions: Digestion|Abdominal Pain|GI Disorders
Interventions: DIETARY_SUPPLEMENT: Radicle GI Health Placebo Control Form 1|DIETARY_SUPPLEMENT: Radicle GI Health Active Study Product 1.1 Usage|DIETARY_SUPPLEMENT: Radicle GI Health Placebo Control Form 2|DIETARY_SUPPLEMENT: Radicle GI Health Active Study Product 2.1 Usage|DIETARY_SUPPLEMENT: Radicle GI Health Active Study Product 2.2 Usage|DIETARY_SUPPLEMENT: Radicle GI Health Placebo Control Form 3|DIETARY_SUPPLEMENT: Radicle GI Health Active Study Product 3.1 Usage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Optimal Antithrombotic Therapy for ACS Patients Concomitant With AF and Implanted With New-generation DES (OPTIMA-3, 4)
Status: RECRUITING
Conditions: Acute Coronary Syndrome (ACS)|Non-valvular Atrial Fibrillation (NVAF)
Interventions: DRUG: Triple antithrombotic therapy|DRUG: Dual antithrombotc therapy-1|DRUG: Dual antithrombotc therapy-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin, Nab-Paclitaxel, and Cetuximab (CACTUX) in Patients With Incurable Head and Neck Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer|Head and Neck Squamous Cell Carcinoma|Cancer of the Head and Neck
Interventions: DRUG: nab-paclitaxel|DRUG: Cisplatin|DRUG: Carboplatin|BIOLOGICAL: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Randomized, Double-Blind, Placebo-Controlled Study of Copolymer 1 for Relapsing-Remitting Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: copolymer 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study Evaluating PSMA Targeted Radionuclide Therapy in Adult Patients With Metastatic Clear Cell Renal Cancer
Status: RECRUITING
Conditions: Metastatic Clear Cell Renal Cell Carcinoma
Interventions: DRUG: 177Lu-PSMA-1 (radiopharmaceutical)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Volume PEG With Low Residue Test Meals Versus High Volume Split-dose PEG Bowel Preparation
Status: COMPLETED
Conditions: Bowel Preparation|Colonoscopy
Interventions: DRUG: Low volume PEG|DRUG: high volume PEG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Amantadine and Transcranial Magnetic Stimulation for Treating Fatigue in Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis|Fatigue
Interventions: DEVICE: Transcranial Magnetic Stimulation|DRUG: Amantadine Hydrochloride 100 mg (milligrams) Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Electrical Stimulation Versus Low-intensity Laser on Motor Conduction Velocity of the Common Peroneal Nerve Post Burn
Status: COMPLETED
Conditions: Neuropathy, Peroneal|Motor Neuropathy|Neuromuscular Electric Stimulation (NEMS)|Low Intensity Laser
Interventions: DEVICE: Neuromuscular electrical stimulation (NMES)|DEVICE: low-intensity laser therapy (LILT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Safety and Efficacy of INCB050465 Combined With Bendamustine and Obinutuzumab in Relapsed or Refractory Follicular Lymphoma (CITADEL-102)
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Parsaclisib|DRUG: Hexal|DRUG: Gazyvaro
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Study to Treat Renal Cell Carcinoma
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Sunitinib (Sutent)|DRUG: Sorafenib (Nexavar)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular Protective Effect of Rosuvastatin in Arteriovenous Fistula
Status: COMPLETED
Conditions: End-stage Kidney Disease|Diabetes Mellitus|Arteriovenous Fistula
Interventions: DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Output Response to Vasopressin Infusion In Abdominal Surgery Patients Under Mechanical Ventilation
Status: COMPLETED
Conditions: Major Abdominal Surgery|General Anesthesia|Mechanical Ventilation|Vasopressin Infusion
Interventions: DRUG: Vasopressin, Arginine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)
Status: NOT_YET_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|OTHER: Electronic Health Record Review|DRUG: Enfortumab Vedotin|OTHER: Immunohistochemistry Staining Method|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Multigated Acquisition Scan|BIOLOGICAL: Sacituzumab Govitecan|BIOLOGICAL: Trastuzumab Deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Liposome for Squamous Non-Small-cell Lung Cancer Study(LIPUSU)
Status: UNKNOWN
Conditions: Squamous Non-small-cell Lung Cancer
Interventions: DRUG: Paclitaxel Liposome|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Inhaled Aromatherapy on Chemo-Induced Nausea Vomiting (NCVI): CINVAROM (Chemotherapy Induced Nausea Vomiting and AROMatherapy)
Status: COMPLETED
Conditions: Nausea and Vomiting|Aromatherapy|Essential Oil|Suportive Care
Interventions: DRUG: Essential oils
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Different Suturing Techniques on the Post-operative Morbidity After Removal of Impacted Mandibular Third Molar
Status: COMPLETED
Conditions: Swelling|Trismus
Interventions: PROCEDURE: partial wound closure|PROCEDURE: total wound closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: First-in-human Study of Interferon-y PET Imaging to Assess Response to Immunotherapy
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: [89Zr]Zr-DFO-emapalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Erlotinib Versus Vinorelbine/Cisplatin as Adjuvant Treatment in Stage IIIA NSCLC Patients With EGFR Mutations
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer Stage IIIA
Interventions: DRUG: Erlotinib|DRUG: vinorelbine/cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pyridostigmine and Its Effects on Autonomic Modulation in Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Complications
Interventions: DRUG: Pyridostigmine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Immersion Level on Respiratory Function of Spinal Cord Injury Patients During Balneotherapy
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: OTHER: Water immersion at cervical level|OTHER: Water immersion at xyphoid level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Evaluate Skin Irritation and Photo Irritation of JNJ 10229570-AAA on Intact Skin of Japanese Healthy Male Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: JNJ 10229570-AAA 1.2% cream|DRUG: JNJ 10229570-AAA 2.4% cream|DRUG: JNJ 10229570-AAA 3.6% cream|DRUG: Color-matched vehicle in a cream formulation containing 0 mg of JNJ 10229570-AAA|DRUG: Petroleum jelly
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Evaluation of the Potential CYP1A2-mediated Drug Drug Interaction Safety, and Tolerability of ABX464
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Caffeine|DRUG: ABX464|DRUG: Fluvoxamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Intermittent Infusion Versus Continuous Infusion of Vancomycin on Kidney Failure in Critically Ill Patients
Status: UNKNOWN
Conditions: Gram-Positive Bacterial Infections|Nephrotoxicity|Sepsis
Interventions: DRUG: Vancomycin Continuous infusion|DRUG: Vancomycin Intermittent infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Midazolam Effect on Agitation Postnasal Surgery
Status: COMPLETED
Conditions: Agitation
Interventions: DRUG: Intravenous midazolam before emergence from general anesthesia|DRUG: Intravenous normal saline before emergence from general anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Pemetrexed Plus Carboplatin, or Pemetrexed Plus Cisplatin With Radiation Therapy Followed by Pemetrexed in Patients With Inoperable Non-Small-Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small-Cell Lung Cancer
Interventions: DRUG: pemetrexed|DRUG: cisplatin|DRUG: carboplatin|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Entinostat and FOLFOX in Subjects With Pancreatic Adenocarcinoma
Status: WITHDRAWN
Conditions: Pancreas Cancer
Interventions: DRUG: Entinostat|DRUG: FOLFOX regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eating Disorders With and Without Childhood Trauma
Status: COMPLETED
Conditions: Eating Disorders|Stress Disorders, Post-traumatic
Interventions: BEHAVIORAL: Cognitive-Behavioural Therapy|BEHAVIORAL: Compassion-Focused Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of ProHydrolase® on the Amino Acid, Intramuscular Anabolic Signaling, and Endocrine Response to Resistance Exercise in Trained Males
Status: COMPLETED
Conditions: Amino Acids
Interventions: DIETARY_SUPPLEMENT: ProHydrolase®|DIETARY_SUPPLEMENT: Whey protein|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Mini-implant Assisted Maxillary Expansion in Adolescents and Adults
Status: NOT_YET_RECRUITING
Conditions: Narrow Maxilla
Interventions: DEVICE: Mini-implants assisted maxillary expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess Safety of Fixed Dose Combination of Dapagliflozin and Saxagliptin in Type 2 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: dapagliflozin and saxagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Two Modalities of Non-invasive Ventilation After Extubation in Very Low Birth Weight Neonates
Status: COMPLETED
Conditions: Preterm Infant
Interventions: OTHER: Nasal Intermittent Positive Pressure|OTHER: Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ACT-129968 in Adult Patients With Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: ACT-129968|DRUG: ACT-129968|DRUG: Cetirizine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effectiveness of Different Anti-HIV Treatments in HIV-Positive Individuals Who Have Been on a Protease Inhibitor-Containing Drug Regimen for at Least 16 Weeks
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Ritonavir|DRUG: Nelfinavir mesylate|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of effectIveness of a Smart Sensor for Continence Care: the ARCTICC Study
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DEVICE: TENA Identifi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The German Project of Heroin Assisted Treatment of Opiate Dependent Patients
Status: COMPLETED
Conditions: Opioid Dependence
Interventions: DRUG: Diacetylmorphine|BEHAVIORAL: Psycho-education and Counselling|DRUG: Methadone|BEHAVIORAL: Case management and Motivational interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Multicenter Study of CVP Followed by Iodine-131 Anti-B1 Antibody for Subjects With Untreated Low-Grade Non Hodgkin's Lymphoma.
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: BIOLOGICAL: cycolophosphamide, vacristine, and pednisone (CVP) x6 cycles followed by tositumomab and iodine I 131 tositumomab.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy of 5% Fluorocalcium Phosphosilicate Dentifrice and Potassium Nitrate Dentifrice on Dentinal Hypersensitivity
Status: COMPLETED
Conditions: Dentinal Hypersensitivity
Interventions: OTHER: 5% fluorocalcium phosphosilicate dentifrice|OTHER: 5% potassium nitrate dentifrice|OTHER: Placebo dentrifice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effect of Oral Doses of 5mg or 10mg of SLx-2101 for 14 Days in Patients With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: SLx-2101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot/Phase II Study of Gamma Knife Radiosurgery for Brain Metastases Using 3Tesla MRI and Rational Dose Selection
Status: TERMINATED
Conditions: Melanoma|Renal Cell Carcinoma|Sarcoma|Breast Cancer|Lung Cancer|Colorectal Cancer|Gastrointestinal Cancers|Brain Metastases
Interventions: PROCEDURE: Gamma Knife Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auditive and Renal Long Term Outcomes - Risk After Aminoglycoside Therapy in Neonates (AURORA)
Status: COMPLETED
Conditions: Hearing Loss|Gentamicin Adverse Reaction|Renal Tubular Disorder
Interventions: DIAGNOSTIC_TEST: Audiometry|DIAGNOSTIC_TEST: Urine biomarkers for renal tubular function|DIAGNOSTIC_TEST: Blood pressure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tolerance and Effect of Antipsychotics in Children and Adolescents With Psychosis
Status: UNKNOWN
Conditions: Psychosis
Interventions: DRUG: Aripiprazole|DRUG: Quetiapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acceptability of a PrEP Program Among MSM and Transgender (TG) and Having Accepted a Targeted Screening for HIV, Hepatitis B (VHB), Hepatitis C (VHC) and STIs.
Status: RECRUITING
Conditions: HIV Infections|STI
Interventions: DIAGNOSTIC_TEST: acceptability of a PrEP program among HIV-negative MSM and TG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Efficacy and Safety of Oral Ranirestat (40 and 80 mg) in Mild to Moderate Diabetic Sensorimotor Polyneuropathy
Status: COMPLETED
Conditions: Mild to Moderate Diabetic Sensorimotor Polyneuropathy
Interventions: DRUG: Ranirestat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carvedilol Versus Metoprolol for the Prevention of Atrial Fibrillation After Off-Pump Coronary Bypass Surgery
Status: COMPLETED
Conditions: Coronary Disease|Atrial Fibrillation
Interventions: DRUG: Carvedilol versus Metoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of ASAQ and PD for the Treatment of Uncomplicated Falciparum Malaria in Mainland Tanzania
Status: COMPLETED
Conditions: Uncomplicated Falciparum Malaria
Interventions: DRUG: Artesunate amodiaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraocular Pressure and Tolerability Study of Preservative-free Prostaglandins (Bimatoprost and Latanoprost) on Glaucoma and Ocular Hypertension: European, Multicentric, Investigator-led, Single Masked Study
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: Preservative-free latanoprost|DRUG: Preservative-free bimatoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does Antibiotics Use During Surgery Help to Decrease Wound Infection and Increase Success After Ear Surgery in Children
Status: COMPLETED
Conditions: Post Operative Wound Infection|Graft Uptake|Myringoplasty
Interventions: DRUG: Co-amoxiclav
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study For 5 Mg Amlodipine Orally-Disintegrating Tablet
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Amlodipine|DRUG: Amlodipine|DRUG: Amlodipine|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NSI Pulsed Electromagnetic Field (PEMF) Biomarker Study
Status: WITHDRAWN
Conditions: Traumatic Brain Injury
Interventions: DEVICE: SofPulse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Benefit and Safety of Older Generation Anti-Epileptic Drugs (AEDs) in Drug-Resistant Epilepsy Children
Status: RECRUITING
Conditions: Drug Resistant Epilepsy
Interventions: DRUG: Valproic acid|DRUG: Carbamazepin|DRUG: Phenytoin|DRUG: Lamotrigine|DRUG: Clobazam|DRUG: Oxcarbazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Gabapentin in Postoperative Pain and Epithelialization After Photorefractive Keratectomy
Status: COMPLETED
Conditions: Pain After Photorefractive Keratectomy
Interventions: DRUG: Gabapentin|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Everolimus and Low-dose Cyclophosphamide in Patients With Metastatic Renal Cell Cancer
Status: COMPLETED
Conditions: Metastatic Renal Cell Cancer
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare (COPD) Assessment Test in COPD Stage III and IV in a Prophylactic Treatment
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: AlphaCore device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Extubation Delay After Prolonged Sedation
Status: UNKNOWN
Conditions: Septic Shock
Interventions: DRUG: Prolonged sedation with isoflurane|DRUG: Prolonged sedation with midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Saline Enema Administration in Meconium Obstruction of Prematurity and Impact on the Resolution, Feeds, Microbiome, and Gut-brain Axis.
Status: RECRUITING
Conditions: Meconium Obstruction of Prematurity
Interventions: PROCEDURE: Saline Enema (SE)|DRUG: Glycerin Suppository
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Cheeky Study: A Novel Delivery System for CAB-RPV LA
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections
Interventions: OTHER: Patient-centered injection site|BEHAVIORAL: Patient-centered adherence support|OTHER: Provider education|BEHAVIORAL: Improved clinic communication strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Preoperative Pembrolizumab Plus Bevacizumab Combined With Chemotherapy in Patients With pMMR/MSS Locally Advanced Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Colorectal Cancer
Interventions: DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Bevacizumab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Latanoprost for the Treatment of Menière's Disease
Status: UNKNOWN
Conditions: Menière's Disease
Interventions: DRUG: Latanoprost|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of KW-3902IV in Combination With IV Furosemide on Renal Function in Subjects With CHF and Renal Impairment
Status: COMPLETED
Conditions: Heart Failure, Congestive|Renal Insufficiency
Interventions: DRUG: KW-3902IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Pharmacokinetics (PK) and Pharmacodymamics (PD) of Ganciclovir (GCV) in Premature Infants Receiving Treatment for Cytomegalorivus (CMV) Infection
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of the Natural Sweeteners Erythritol and Xylitol on Gut Microbiota and Glucose Metabolism in Obese Volunteers
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: E967-Xylitol|DIETARY_SUPPLEMENT: E968-Erythritol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: "Evaluation of Clinical Performance and Success Rate of CAD/CAM Versus Conventional Band and Loop Space Maintainer"
Status: NOT_YET_RECRUITING
Conditions: CAD/CAM Space Maintainer
Interventions: DEVICE: CAD/CAM zircon band and loop space maintainer|DEVICE: Conventional metal band and loop space maintainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fortified Oral Rehydration Therapy for Pediatric Diarrhea
Status: RECRUITING
Conditions: Acute Gastroenteritis
Interventions: DRUG: Fortified Oral Rehydration Therapy|DIETARY_SUPPLEMENT: Standard of Care Oral Rehydration Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dane County Safety Assessment for Elders (SAFE) Research Study
Status: COMPLETED
Conditions: Falls
Interventions: BEHAVIORAL: Individualized multifactorial intervention for community-living high-risk older adults|BEHAVIORAL: Health professional education program about fall prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Feasibility of Expressive Writing for Body Image Distress and Anxiety Among Adolescent and Young Adult Cancer Survivors
Status: NOT_YET_RECRUITING
Conditions: Adolescent Cancer|Young Adult Cancer|Body Image
Interventions: OTHER: BI Focused writing|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Dry Needling on Function, Muscle Tone and Quality of Life in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: OTHER: Dry needling|OTHER: Sham dry Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Audiovisual Distraction on Desaturation and Airway Intervention in OSA-patients
Status: COMPLETED
Conditions: Obstructive Sleep Apnea (OSA)
Interventions: DEVICE: Audiovisual Distraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Assess the Efficacy and Safety of Transplanting Autologous Skeletal Myoblasts, Into Infarcted Heart, Using an Catheter Delivery System
Status: UNKNOWN
Conditions: Ischemic Cardiomyopathy
Interventions: BIOLOGICAL: myoblast|BIOLOGICAL: sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HepTcell Immunotherapy in Patients With Inactive Chronic Hepatitis B (CHB)
Status: TERMINATED
Conditions: Hepatitis B, Chronic
Interventions: BIOLOGICAL: HepTcell|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Amantadine and Temporal Discrimination in Patients With Traumatic Brain Injury (TBI)
Status: WITHDRAWN
Conditions: Traumatic Brain Injury
Interventions: DRUG: amantadine|DRUG: amantadine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II Palbociclib +Ibrutinib in Mantle Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Mantle Cell Lymphoma|B Cell Lymphoma
Interventions: DRUG: Palbociclib|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Pilot Study Comparing Two Vacuum-wound-dressings for Open Abdomen Treatment
Status: TERMINATED
Conditions: Open Abdomen|Temporary Abdominal Closure
Interventions: PROCEDURE: Vacuum-Pack-technique for temporary abdominal closure|PROCEDURE: Abdominal-dressing-technique for temporary abdominal closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Crossover Acceptability Study Assessing a DPP Capsule for HIV and Pregnancy Prevention
Status: COMPLETED
Conditions: HIV Infections|Contraception
Interventions: DRUG: Dual Prevention Pill|DRUG: PrEP and combined oral contraceptive (COC) as two separate tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Ganfort Versus Duotrav in Patients With Primary Open Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Ocular Hypertension|Primary Open Angle Glaucoma
Interventions: DRUG: Ganfort|DRUG: Duotrav
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reinfusion Drains vs Tranexamic Acid in Total Joint Arthroplasty
Status: COMPLETED
Conditions: Total Joint Arthroplasty
Interventions: PROCEDURE: Hemovac drain|PROCEDURE: Re-infusion drain|PROCEDURE: Tranexamic drain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Transcranial Magnetic Stimulation to the Frontoparietal Attention Network on Anxiety Potentiated Startle
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Transcranial Magnetic Stimulation Sham|DEVICE: Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The IndONEsia ICCU Registry: a Multicenter Cohort of Intensive Cardiovascular Care Units Patients in Indonesia
Status: COMPLETED
Conditions: Cardiovascular Diseases|Acute Coronary Syndrome|Heart Failure|Heart Disease, Coronary|Infections|Sepsis|Stroke|Shock|Chronic Kidney Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p