pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: American Ginseng Extract in Preventing Respiratory Infection and in Reducing Antibiotic Use in Patients With CLL
Status: COMPLETED
Conditions: Leukemia
Interventions: DIETARY_SUPPLEMENT: American ginseng|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Pharmacokinetics, Safety, and Tolerability of Doravirine (MK-1439) and Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate (MK-1439A) in HIV-1-Infected Children and Adolescents
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Doravirine (DOR)|DRUG: Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate (DOR/3TC/TDF)|DRUG: Antiretroviral (ARV) medications
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A SAD/MAD to Assess the Safety, PK/PD of FT-4202 in Healthy Volunteers and Sickle Cell Disease Patients
Status: COMPLETED
Conditions: Healthy Volunteers|Sickle Cell Disease
Interventions: DRUG: FT-4202/Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Comparing Mucinex Extended-release 600 mg Tablets to Immediate-release Guaifenesin 600 mg in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Mucinex® SE|DRUG: Vicks Cough Syrup for Chesty Coughs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pharmacodynamics, Safety, and Pharmacokinetics Study of THN201 Versus Donepezil in Healthy Male Volunteers
Status: COMPLETED
Conditions: Cognitive Impairment|Alzheimer Disease
Interventions: DRUG: THN 201|DRUG: Donepezil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety of Alpelisib Plus Fulvestrant, in Men and Post-menopausal Women With HR-positive, HER2-negative, Advanced Breast Cancer (aBC) With PIK3CA Mutation, Whose Disease Progressed on or After Endocrine Treatment
Status: RECRUITING
Conditions: Advanced Breast Cancer
Interventions: DRUG: Alpelisib|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Depsipeptide (Romidepsin) in Treating Patients With Recurrent Ovarian Epithelial or Peritoneal Cavity Cancer
Status: TERMINATED
Conditions: Primary Peritoneal Cavity Cancer|Recurrent Ovarian Epithelial Cancer
Interventions: DRUG: romidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exer-game Balance Training on Dementia
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: OTHER: Exergaming low intensity group|OTHER: Exergaming moderate intensity group|OTHER: Exergaming high intensity group|OTHER: control group exergaming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Tolerability of ABBV-0805 in Patients With Parkinson's Disease
Status: WITHDRAWN
Conditions: Parkinson's Disease
Interventions: DRUG: ABBV-0805|DRUG: Placebo ABBV-0805
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Radial Strain for Assessment of Left Ventricular Function in Transesophageal Echocardiography
Status: UNKNOWN
Conditions: Ventricular Function, Left
Interventions: PROCEDURE: TEE (transesophageal echocardiography)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Smartphone Application on Reducing Localized Inflammation in Periodontal Maintenance Patients
Status: COMPLETED
Conditions: Periodontal Inflammation
Interventions: OTHER: Brushlink application|OTHER: Water-flosser|OTHER: Interproximal brush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and Carboplatin in Treating Patients With Metastatic, Castration Resistant Prostate Cancer Containing Inactivated Genes in the BRCA 1/2 Pathway
Status: COMPLETED
Conditions: Castration Levels of Testosterone|Castration-Resistant Prostate Carcinoma|Metastatic Prostate Carcinoma|Prostate Carcinoma Metastatic in the Bone|PSA Progression|Stage IV Prostate Cancer
Interventions: DRUG: Carboplatin|DRUG: Docetaxel|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of Efficacy and Tolerability of Sacituzumab-Govitecan in the Treatment of Patients With Triple-negative Breast Cancer in the Metastatic Phase: Prospective Multicenter Real-world Study
Status: RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fluorouracil, Leucovorin, and Irinotecan in Treating Patients With Recurrent or Refractory Metastatic Unresectable Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFIRI regimen|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Pre-Exposure Prophylaxis (PrEP) Administered at Sexually Transmitted Disease (STD) Clinics
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: FTC 200 mg/TDF 300 mg fixed-dose combination tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of CEP-9722 as Single-Agent Therapy and as Combination Therapy With Temozolomide in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: CEP-9722
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anxiolysis for Laceration Repair in Children
Status: RECRUITING
Conditions: Laceration of Skin|Distress, Emotional
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam Nasal Spray|DRUG: Nitrous oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: [Study Evaluating the Efficacy and Safety of a Digital Therapeutic as an Adjunct to TAU in Postpartum Depression]
Status: TERMINATED
Conditions: Postpartum Depression
Interventions: DEVICE: WB001|DEVICE: ED001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Capecitabine (Xeloda) and Bevacizumab as a First-line Therapy in Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Oxaliplatin 130 mg/m^2|DRUG: Capecitabine 1000 mg/m^2|DRUG: Bevacizumab 7.5 mg/kg|DRUG: Placebo for bevacizumab 7.5 mg/kg|DRUG: Oxaliplatin 85 mg/m^2|DRUG: Leucovorin 200 mg/m^2|DRUG: Fluorouracil 400 mg/m^2|DRUG: Bevacizumab 5 mg/kg|DRUG: Placebo for bevacizumab 5 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dapagliflozin on Kidney Function (Glomerular Filtration Rate) in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Dapagliflozin|DRUG: Placebo|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Application of Lens Dysfunction Index (DLI) in the Timing of Age-related Cataract Surgery
Status: UNKNOWN
Conditions: Age-Related Cataract
Interventions: DEVICE: measure the preoperative DLI、 SS-OCT image of the lens,、take photos of the anterior segment and self-scoring of the preoperative visual quality assessment scale.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Increasing Colorectal Cancer Screening in African Americans
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: OTHER: informational intervention|OTHER: medical chart review|OTHER: screening questionnaire administration|OTHER: study of socioeconomic and demographic variables|PROCEDURE: barium enema injection|PROCEDURE: colon imaging study|PROCEDURE: screening colonoscopy|PROCEDURE: sigmoidoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Open Label Single Arm Proof of Concept Trial to Evaluate the Efficacy and Safety of Cytori Celution System in Diabetic Leg Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer|Leg Ulcer|Autologous Adipose Stromal Vascular Fraction|Mesenchymal Stem Cells|Adipose-Derived Mesenchymal Stem Cells
Interventions: DEVICE: Diabetic leg ulcer treatment with adipous SVF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Properties of Dietary Fibre and Energy Intake
Status: COMPLETED
Conditions: Healthy Male Subjects
Interventions: DIETARY_SUPPLEMENT: control: no fiber addition|DIETARY_SUPPLEMENT: breakfast with low viscous, low gelling pectin|DIETARY_SUPPLEMENT: high viscous, low gelling pectin|DIETARY_SUPPLEMENT: low viscous, high gelling pectin|DIETARY_SUPPLEMENT: high viscous, high gelling pectin|DIETARY_SUPPLEMENT: pectin supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Remifentanil-dexmedetomidine Compared With Remifentanil-midazolam on Patient's Satisfaction
Status: COMPLETED
Conditions: Peripheral Arterial Occlusive Disease
Interventions: DRUG: dexmedetomidine|DRUG: midazolam|DRUG: remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Remifentanil Infusion During Emergence on the Incidence of Emergence Delirium
Status: UNKNOWN
Conditions: Delirium
Interventions: DRUG: Remifentanil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Problem Solving Based Intervention for Facilitating Return-to-work Among People Suffering From Common Mental Disorders
Status: COMPLETED
Conditions: Depression|Anxiety Disorders|Adjustment Disorders|Common Mental Disorder
Interventions: BEHAVIORAL: Problem solving based intervention|BEHAVIORAL: Care as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Japanese Study With Rimonabant in Obese Type 2 Diabetic Patients With Oral Anti-diabetic Drug
Status: TERMINATED
Conditions: Obesity|Diabetes Mellitus Type 2
Interventions: DRUG: Rimonabant|DRUG: Placebo (for Rimonabant)|DRUG: Anti-diabetic monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating SOM230 in Patients With Metastatic Carcinoid Tumors
Status: COMPLETED
Conditions: Carcinoid Tumors
Interventions: DRUG: Pasireotide (SOM230)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Polyethylene-Glycol-Conjugated Interleukin 2 in Patients With Common Variable Immunodeficiency
Status: COMPLETED
Conditions: Common Variable Immunodeficiency
Interventions: DRUG: PEG-interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of A2 Milk on Gastrointestinal Function in Non-lactose Milk Intolerance
Status: COMPLETED
Conditions: Milk Intolerance
Interventions: DIETARY_SUPPLEMENT: A2 milk 100|DIETARY_SUPPLEMENT: A2 milk 150|DIETARY_SUPPLEMENT: A2 milk 200|DIETARY_SUPPLEMENT: A2 milk 250|DIETARY_SUPPLEMENT: A1/A2 milk 100|DIETARY_SUPPLEMENT: A1/A2 milk 150|DIETARY_SUPPLEMENT: A1/A2 milk 200|DIETARY_SUPPLEMENT: A1/A2 milk 250
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ultrasound for Confirmation of Gastric Tube Placement in Critically Ill Patients Under Invasive Mechanical Ventilation
Status: TERMINATED
Conditions: Ultrasound for Confirmation of Gastric Tube Placement in Critically Ill Patients Under Invasive Mechanical Ventilation
Interventions: DIAGNOSTIC_TEST: ultrasonography (US)|DIAGNOSTIC_TEST: Standard routine (SR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Iberdomide Alone or in Combination With Dexamethasone for the Treatment of Intermediate- or High-Risk Smoldering Multiple Myeloma
Status: RECRUITING
Conditions: Smoldering Plasma Cell Myeloma
Interventions: DRUG: Dexamethasone|DRUG: Iberdomide Hydrochloride|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of a Single Intravenous Infusion of XTMAB-16 in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: XTMAB-16 2mg/kg|DRUG: Placebo|DRUG: XTMAB-16 4mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: TheTreatment of Acne Scar Using UltraPulse CO2 Laser
Status: UNKNOWN
Conditions: Acne Scar
Interventions: DEVICE: High energy (UltraPulse)|DEVICE: Low energy (UltraPulse)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HFNO Reducing the Incidence of Hypoxia for Hysteroscopy Sedated With Propofol
Status: UNKNOWN
Conditions: Endometritis|Tuberculous Endometritis|Subseptate Uterus|Endometrial Polyps
Interventions: DEVICE: High Flow Nasal Cannula oxygen (HFNO)|DEVICE: Regular oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of a Live Attenuated H7N9 Influenza Virus Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Influenza A Virus, H7N9 Subtype
Interventions: BIOLOGICAL: Live attenuated H7N9 A/Anhui/13 ca influenza virus vaccine|BIOLOGICAL: Inactivated subvirion H7N9 influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Anterior Cutaneus Nerve and Distal Adductor Canal Block With USG for Total Knee Replacement Analgesia
Status: COMPLETED
Conditions: Pain Measurement|Knee Replacement Arthroplasty|Nerve Block
Interventions: PROCEDURE: Adductor canal blockade|PROCEDURE: Distal adductor canala blockade and anterior cutaneus nerve blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tocilizumab to Prevent Clinical Decompensation in Hospitalized, Non-critically Ill Patients With COVID-19 Pneumonitis
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Tocilizumab|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proprioceptive Training and Low Back Pain
Status: COMPLETED
Conditions: Proprioceptive Training|Low Back Pain
Interventions: OTHER: Proprioceptive training|OTHER: Sham proprioceptive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Tolerability and Efficacy of BVS857 in Severe Burn Subjects
Status: TERMINATED
Conditions: Hypercatabolic Status Related to Severe Burn
Interventions: BIOLOGICAL: BVS857|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Specimen and Data Study for Ovarian Cancer Early Detection and Prevention
Status: RECRUITING
Conditions: Cervical Cancer|Endometrial Cancer|Fallopian Tube Cancer|Hereditary Breast/Ovarian Cancer (brca1, brca2)|Ovarian Cancer|Sarcoma|Uterine Leiomyomata|Vaginal Cancer|Vulvar Cancer
Interventions: OTHER: Ca-125|OTHER: screening questionnaire administration|PROCEDURE: Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Playful Cognitive-motor Mobility Training on Balance, Gait and Cognition and on the Prevention of Falls in Seniors
Status: UNKNOWN
Conditions: Fall Patients
Interventions: BEHAVIORAL: training with Cycléo device (COTTOS ®),|OTHER: non intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: General Anesthesia With ETT vs LMA in Patients Undergoing Ablation for Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: General Anesthesia with endotracheal tube|DEVICE: General Anesthesia with laryngeal mask airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Laparoscopic Right Hemicoloectomy for Right Colon Cancer With a Medial-to-lateral Approach Orientated by SMA or SMV
Status: UNKNOWN
Conditions: Right Colic Lymphadenopathy
Interventions: PROCEDURE: SMA-orientated right hemicoloectomy|PROCEDURE: SMV-orientated right hemicoloectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Scleral Contact Lenses for Daily Wear for Regular and Irregular Refractive Errors Compared to Habitually Worn Scleral Lenses
Status: COMPLETED
Conditions: Scleral Lens Wearers
Interventions: DEVICE: scleral contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Efficacy of Mutaflor(E. Coli Nissle 1917, Mutaflor®) for Chronic Constipation:Multicenter Study
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: E. coli Nissle 1917(Mutaflor®)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Liquid Biopsy for Early Non-small Lung Cancer Detection
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small-cell Lung Cancer
Interventions: DIAGNOSTIC_TEST: Liquid biopsy for aberrant DNA methylation analysis - Indeterminate pulmonary nodule|DIAGNOSTIC_TEST: Liquid biopsy for aberrant DNA methylation analysis - Known lung cancer for surgical resection|DIAGNOSTIC_TEST: Liquid biopsy for aberrant DNA methylation analysis - Healthy volunteer|DIAGNOSTIC_TEST: Liquid biopsy for aberrant DNA methylation analysis - Benign lung disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Oral Hyaluronic Acid for the Prevention of Aromatase Inhibitor-Associated Arthralgias
Status: WITHDRAWN
Conditions: Breast Neoplasm Female|Arthralgia
Interventions: DRUG: Hyaluronic Acid (HA)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Xevinapant With Radiation and Chemotherapy for Patients With Head and Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer|Head and Neck Neoplasms|Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: Xevinapant|DRUG: Carboplatin|DRUG: Paclitaxel|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Prophylactic Negative Pressure Wound Therapy (NPWT)
Status: RECRUITING
Conditions: Wound of Skin
Interventions: DEVICE: PICO7|OTHER: usual care dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: BAFFR Targeting CAR-T Cells for the Treatment of Relapsed or Refractory B-cell ALL
Status: RECRUITING
Conditions: Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: BAFFR-CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Extra Virgin Olive Oil on Atherosclerosis Biomarkers in HIV-infected Patients
Status: COMPLETED
Conditions: HIV|Atherosclerosis|HIV Infections
Interventions: OTHER: consumption 1. EVOO; 2. ROO|OTHER: consumption 1. ROO; 2. EVOO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of Unesbulin (PTC596) in Combination With Dacarbazine in Participants With Advanced Leiomyosarcoma (LMS)
Status: COMPLETED
Conditions: Leiomyosarcoma
Interventions: DRUG: Unesbulin|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma
Status: COMPLETED
Conditions: Childhood Alveolar Soft Part Sarcoma|Childhood Angiosarcoma|Childhood Epithelioid Sarcoma|Childhood Fibrosarcoma|Childhood Gliosarcoma|Childhood Leiomyosarcoma|Childhood Liposarcoma|Childhood Malignant Peripheral Nerve Sheath Tumor|Childhood Synovial Sarcoma|Previously Treated Childhood Rhabdomyosarcoma|Recurrent Childhood Rhabdomyosarcoma|Recurrent Childhood Soft Tissue Sarcoma|Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Recurrent Osteosarcoma|Rhabdomyosarcoma
Interventions: BIOLOGICAL: Cixutumumab|OTHER: Laboratory Biomarker Analysis|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Stellate Ganglion Block on Drooling in Parkinson's Syndrome
Status: NOT_YET_RECRUITING
Conditions: Parkinson's Syndrome
Interventions: BEHAVIORAL: Comprehensive rehabilitation|PROCEDURE: Stellate ganglion block|DRUG: Lidocaine hydrochloride|PROCEDURE: Placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study in Children, 6 Months to 3 Years of Age, to Assess Two Dose Levels of an Experimental Flu Vaccine, Using a Licensed Influenza Virus Vaccine, Vaxigrip® as the Control
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GSK Biologicals' influenza vaccine GSK1557482A|BIOLOGICAL: Vaxigrip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Learn More About MAC Disease and the Use of Anti-HIV Drugs in Patients With Advanced HIV Infection
Status: COMPLETED
Conditions: Mycobacterium Avium-intracellulare Infection|HIV Infections
Interventions: DRUG: Nelfinavir mesylate|DRUG: Nevirapine|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Intervention Plan Aimed at the Diaphragm in Chronic Non-specific Neck Pain
Status: NOT_YET_RECRUITING
Conditions: Chronic Neck Pain
Interventions: OTHER: Placebo technique|OTHER: Diaphragm protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Laryngeal Mask Airway (LMA) - Unique and LMA-Supreme in Children
Status: COMPLETED
Conditions: Laryngeal Mask Airway in Children
Interventions: DEVICE: LMA Unique: control device|DEVICE: LMA Supreme: comparison device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Pirtobrutinib and Venetoclax in Waldenström Macroglobulinemia
Status: RECRUITING
Conditions: Waldenstrom Macroglobulinemia
Interventions: DRUG: Pirtobrutinib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Moderate Sedation for Dental Treatment of Young Children
Status: COMPLETED
Conditions: Dental Caries|Child Behavior|Conscious Sedation Failure During Procedure
Interventions: DRUG: Midazolam|BEHAVIORAL: Protective stabilization|DRUG: Midazolam, ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Indoleamine 2,3-dioxygenase Activity, Serum Levels of Cytokines, BDNF, BH4 and Mirtazapine Efficacy in Fibromyalgia Syndrome
Status: COMPLETED
Conditions: Fibromyalgia Syndrome
Interventions: DRUG: mirtazapine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Animal Assisted Interactions With Animal Robot During PT/OT in the ICU
Status: COMPLETED
Conditions: Pediatric ALL|Critical Illness|Physical Therapy Modalities|Occupational Therapy|Animal Assisted Therapy
Interventions: DEVICE: PARO therapy seal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of an Individualized Exergame Training for Older Adults With MI and/or UI (VITAAL)
Status: UNKNOWN
Conditions: Urinary Incontinence|Mobility Impairment|Older Adults
Interventions: BEHAVIORAL: VITAAL Exergame|BEHAVIORAL: Conventional Training UI|BEHAVIORAL: Conventional Training MI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of AK111 in Subjects With Active Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: BIOLOGICAL: AK111|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunity in Persons Fully Vaccinated Against Measles, Mumps and Rubella and Responses to Booster Vaccination
Status: RECRUITING
Conditions: Mumps|Measles|Rubella
Interventions: BIOLOGICAL: MMR booster vaccination (as M-M-R-VaxPro)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Eplerenone on Novel Biomarkers of Mineralocorticoid Receptor Activation (ENOVA)
Status: WITHDRAWN
Conditions: Hypertension
Interventions: DRUG: Placebo|DRUG: Eplerenone 50mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Understanding Alcohol Reward in Social Context
Status: COMPLETED
Conditions: Alcohol Drinking|Alcohol Use Disorder|Alcohol Intoxication|Alcohol; Harmful Use|Alcoholism|Binge Drinking
Interventions: DRUG: Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Using Intranasal Midazolam (INM) and Lidocaine for Uncooperative Children
Status: COMPLETED
Conditions: Burning Nose
Interventions: DRUG: Midazolam|DRUG: Lidocaine-Midazolam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Effectiveness of Therapy Timely Adjustment Based on Self-monitoring in Patients Suffering From Mild-to-moderate Ulcerative Colitis (OPTIMISE Study)
Status: COMPLETED
Conditions: Mild-to-moderate Ulcerative Colitis
Interventions: OTHER: Faecal Calprotectin Home Test|OTHER: PRO-2 Scoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trimodal Lung-Sparing Treatment of Pleural Mesothelioma
Status: TERMINATED
Conditions: Pleural Mesothelioma
Interventions: DRUG: Doxorubicin|DRUG: Cisplatin|DRUG: Pemetrexed|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ketoprofen Gel to Placebo in Mechanical Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: DRUG: Fastjel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of Additional Arthroscopic Portals in Diagnosis of Hidden Lesions of the Medial Meniscus in Pediatrics Knees With ACL Deficiency
Status: COMPLETED
Conditions: Chronic Knee Instability
Interventions: PROCEDURE: Arthroscopic intercondylar and posteromedial portal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Minimisation of Blood Pressure Variability and Postoperative Nausea and Vomiting
Status: RECRUITING
Conditions: PONV|Blood Pressure|Postoperative Recovery
Interventions: OTHER: Minimizing blood pressure variability
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy, Safety, and Tolerability of TD1414 2% Cream in Impetigo and Secondarily Infected Traumatic Lesions (SITL)
Status: COMPLETED
Conditions: Impetigo|Secondarily Infected Traumatic Lesions
Interventions: DRUG: TD1414 2% cream|DRUG: TD1414 2% cream|DRUG: Bactroban® (mupirocin) 2% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CTI Ablation Guided by Omnipolar Wave Speed and Voltage Maps to Diminish RF and Fluoroscopy Times
Status: RECRUITING
Conditions: Flutter
Interventions: PROCEDURE: Confluent areas|PROCEDURE: Wave Speed|PROCEDURE: Voltage|PROCEDURE: CTI line
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy, and Pharmacokinetics of SKY0402 Administered as a Nerve Block in Subjects Undergoing Bunionectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: SKY0402|DRUG: Bupivacaine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Acetaminophen/Naproxen Sodium Fixed Combination Tablets in Adolescents 12 to <17 Years of Age With Pain
Status: COMPLETED
Conditions: Orthodontic Pain
Interventions: DRUG: Acetaminophen/Naproxen Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Oxaliplatin+Gemcitabine vs Capecitabine as Adjuvant Therapy for Intrahepatic Cholangiocarcinoma
Status: UNKNOWN
Conditions: Cholangiocarcinoma
Interventions: DRUG: oxaliplatin and gemcitabine|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Eteplirsen in Young Participants With Duchenne Muscular Dystrophy (DMD) Amenable to Exon 51 Skipping
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Eteplirsen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Finding Study of HP802-247 in Venous Leg Ulcers
Status: COMPLETED
Conditions: Venous Leg Ulcer|Venous Stasis Ulcers
Interventions: BIOLOGICAL: HP802-247|BIOLOGICAL: Placebo (Vehicle)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Radial EBUS Versus VBN for the Peripheral Pulmonary Lesions
Status: RECRUITING
Conditions: Lung Cancer|Tuberculosis|Pneumonia
Interventions: DIAGNOSTIC_TEST: Virtual bronchoscopy navigation|DIAGNOSTIC_TEST: radial EBUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ultrasound Imaging Based Sensing of Human Ankle Motion Intent and Control Strategies for Ankle Assistance
Status: UNKNOWN
Conditions: Incomplete Spinal Cord Injury|Transverse Myelitis
Interventions: DEVICE: Surface electromypgraphy-based interface to predict human ankle joint motion intent and use in ankle assistive devices|DEVICE: Ultrasound imaging-based interface to predict human ankle joint motion intent and use in ankle assistive devices|DEVICE: Surface electromypgraphy and ultrasound imaging-based interface to predict human ankle joint motion intent and use in ankle assistive devices
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Short-term Chinese Tea-flavor Liquor Consumption
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Tea-flavor Liquor|DIETARY_SUPPLEMENT: Guizhou Meijiao Liquor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Lung Carcinoma|Non-Small Cell Lung Carcinoma|Small Cell Lung Carcinoma|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8
Interventions: DRUG: Porfimer Sodium|PROCEDURE: Ultrasound-Guided Transbronchial Needle-Delivered Interstitial Photodynamic Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biochemical Recurrence Rate of Radical Prostatectomy Combined With Neoadjuvant and Adjuvant Chemotherapy in High Risk Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: DOCETAXEL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study of Glyceryl Tri-(4-phenylbutyrate) Administered Orally as a Single Dose, and Twice Daily for Seven Consecutive Days to Subjects With Hepatic Impairment With Cirrhosis and to a Control Group
Status: COMPLETED
Conditions: Hepatic Encephalopathy|Urea Cycle Disorders
Interventions: DRUG: HPN-100
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Pharmacotherapy for Alcoholism and Alcohol Liver Disease
Status: COMPLETED
Conditions: Alcoholism,|Alcoholic Liver Disease
Interventions: DRUG: Metadoxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 24 Week Clinical Trial to Evaluate Safety and Effectiveness of a Hair Growth System to Treat Male and Female Baldness
Status: UNKNOWN
Conditions: Androgenetic Alopecia
Interventions: DEVICE: iRestore Hair Rejuvenation System|DEVICE: sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antiviral Long Acting Drugs Landing in People Living With HIV
Status: NOT_YET_RECRUITING
Conditions: HIV|Antiviral Agents
Interventions: OTHER: Surveys completion|DRUG: Home administration of CAB+RPV|DRUG: Hospital administration of CAB+RPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-escalation Study of Safety of PBCAR20A in Subjects With r/r NHL or r/r CLL/SLL
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma, Relapsed|Chronic Lymphoid Leukemia in Relapse|Non-Hodgkin's Lymphoma Refractory|Chronic Lymphocytic Leukemia|Lymphoma, Non-Hodgkin|Leukemia, Lymphocytic, Chronic|B-cell Chronic Lymphocytic Leukemia|B-cell Non Hodgkin Lymphoma|Small Lymphocytic Lymphoma
Interventions: GENETIC: PBCAR20A|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Levator Muscle Reaction for Unilateral Congenital Ptosis Repair as Compared to Levator Plication
Status: NOT_YET_RECRUITING
Conditions: Congenital Ptosis
Interventions: PROCEDURE: levator muscle resection|PROCEDURE: levator muscle plication
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lipid Formulation to Increase the Bioavailability of Fatty Acids in Cystic Fibrosis (CF) Patients
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DIETARY_SUPPLEMENT: modified lipid formulation|DIETARY_SUPPLEMENT: Fish oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Amlodipine vs Nitrates Study in Patients With Chronic Stable Angina
Status: COMPLETED
Conditions: Myocardial Ischemia
Interventions: DRUG: Amlodipine|DRUG: iso- 5 - mononitrate|PROCEDURE: Blood tests|PROCEDURE: Exercise Stress Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain After Pulpectomy of Primary Molars Using Different Obturation Materials
Status: UNKNOWN
Conditions: Post Operative Pain
Interventions: OTHER: Metapex|OTHER: Endoflas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Response Study of EMA401 in Patients With Post-herpetic Neuralgia (PHN)
Status: TERMINATED
Conditions: Post-herpetic Neuralgia
Interventions: DRUG: EMA401|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study With BPS-314d-MR-PAH-303 in Participants With Pulmonary Arterial Hypertension
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Esuberaprost|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability and Efficacy Study of V158866 in Central Neuropathic Pain Following Spinal Cord Injury
Status: COMPLETED
Conditions: Neuropathic Pain Due to Spinal Cord Injury
Interventions: DRUG: V158866|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label Study Using ASP-1929 Photoimmunotherapy in Combination With Anti-PD1 Therapy in EGFR Expressing Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Head and Neck Squamous Cell Carcinoma|Metastatic Head-and-neck Squamous-cell Carcinoma|Locally Advanced Cutaneous Squamous Cell Carcinoma|Metastatic Cutaneous Squamous Cell Carcinoma
Interventions: BIOLOGICAL: 200 mg Pembrolizumab|BIOLOGICAL: 350 mg Cemiplimab|COMBINATION_PRODUCT: ASP-1929
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, Food Effect, and Pharmacokinetics of JNJ-54416076 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-54416076|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Modulated Light Therapy in Participants With Pattern Hair Loss
Status: COMPLETED
Conditions: Androgenetic Alopecia
Interventions: DEVICE: REVIAN 101|DEVICE: REVIAN 102|DEVICE: REVIAN 103|DEVICE: REVIAN 100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MITE in the Treatment of Dyspepsia After Cholecystectomy
Status: UNKNOWN
Conditions: Patients With Dyspeptic Symptoms After Cholecystectomy
Interventions: DRUG: Compound Azintamide Enteric-coated Tablets|DRUG: Oryz-aspergillus Enzyme both Pancreatin Tablet and Ursodeoxycholic Acid Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EpiFaith CV for Central Venous Catheterization
Status: NOT_YET_RECRUITING
Conditions: Catheterization, Central Venous|Equipment Design|Patient Safety|Anesthesiology Devices Associated With Misadventures, Diagnostic and Monitoring Devices|Perioperative Care
Interventions: DEVICE: EpiFaith CV|DEVICE: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Omega-3 Fatty Acids and Chemotherapy-induced Neuropathy and Inflammation in Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DIETARY_SUPPLEMENT: oil fish|OTHER: corn oil pearls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Peginesatide (AF37702) in the Treatment of Anemia in Participants With Chronic Kidney Disease
Status: COMPLETED
Conditions: Anemia|Chronic Kidney Disease|Chronic Renal Failure|Pure Red Cell Aplasia
Interventions: DRUG: Peginesatide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Improvement of Myocardial Microcirculation After Acute Anterior Myocardial Infarction
Status: NOT_YET_RECRUITING
Conditions: Intravascular Imaging and Microvascular Obstruction
Interventions: PROCEDURE: OCT-guided PCI|PROCEDURE: 60 MHz HD-IVUS-guided PCI|PROCEDURE: Angiography-guided PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Efficacy and Safety Of Intravesical Nanoxel®M In BCG Refractory NMIBC
Status: TERMINATED
Conditions: Non Muscle Invasive Bladder Cancer
Interventions: DRUG: Nanoxel®M|DRUG: Mitomycin-C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About How BAY2927088 Affects the Level of Dabigatran or Rosuvastatin in the Blood When These Drugs Are Taken Together in Healthy Participants
Status: COMPLETED
Conditions: Advanced Non-small Cell Lung Cancer|EGFR Mutation|HER2 Mutation|Healthy Volunteers
Interventions: DRUG: BAY2927088|DRUG: Dabigatran etexilate|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase I, Study in Chinese NSCLC Patients
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung With EGFR Mutation Positive
Interventions: DRUG: AZD9291 40 mg|DRUG: AZD9291 80 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effectiveness and Safety of Sphaeralcea Angustifolia Standardized Extract as a Topical Treatment of Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: Standardized extract of Sphaeralcea angustifolia|DRUG: Diclofenac Sodium Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Titanium Niobium Nitride Coating in Total Knee Arthroplasty
Status: TERMINATED
Conditions: Knee Arthritis
Interventions: DEVICE: GKS Prime Flex Bioloy by Permedica, a TiNbN coated fixed-bearing cruciate-retaining total knee prosthesis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Increasing Physical Activity in Older Adults With Osteoarthritis Pain: Examining a Brief Behavioral Intervention
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Osteoarthritis, Hip
Interventions: BEHAVIORAL: Engage PA|OTHER: Treatment as Usual plus (TAU+)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT