pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Quantitative Evaluation of Osteopathic Treatment in Temporomandibular Joint Disorders Using Magnetic Resonance Imaging
Status: UNKNOWN
Conditions: Temporomandibular Disorders, Articular Disc Disorder (Reducing or Non-Reducing)|Osteopathy in Temporomandibular Disorders
Interventions: OTHER: Occlusal Splint Treatment|OTHER: Osteopathic Manual Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Of Femoral Block And Middle Adductor Canal Block In Patients With Knee Arthroplasty
Status: UNKNOWN
Conditions: Arthroplasty, Replacement, Knee|Pain, Postoperative|Anesthesia and Analgesia|Anesthesia, Conduction|Nerve Block
Interventions: PROCEDURE: Ultrasound Guided Middle Adductor Canal Block|PROCEDURE: Ultrasound Guided Femoral Nerve Block.|DRUG: Bupivacain|PROCEDURE: Spinal Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: CHESS Criteria for Varices Screening in Compensated Advanced Chronic Liver Disease (CHESS2001/APPHA2001)
Status: COMPLETED
Conditions: Compensated Advanced Chronic Liver Disease|Varices Needing Treatment
Interventions: PROCEDURE: Esophagogasrtoduodendoscopy, liver stiffness measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Exploratory Haemodynamic Study in Patients With Compensated Cirrhosis and Portal Hypertension
Status: COMPLETED
Conditions: Compensated Cirrhosis and Portal Hypertension
Interventions: DRUG: Terlipressin acetate|DRUG: Serelaxin (RLX030)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients
Status: RECRUITING
Conditions: Anesthesia|Intravenous Fluid|Blood Pressure
Interventions: OTHER: Lung Recruitment Maneuver|OTHER: Fluid Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ELEONOR STUDY: Insulin Glulisine in Type 2 Diabetes Mellitus.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin glulisine|DRUG: Insulin glargine|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Airway Pressure Release Ventilation (APRV) Protocol Early Used in Acute Respiratory Distress Syndrome
Status: UNKNOWN
Conditions: Acute Respiratory Distress Syndrome
Interventions: DEVICE: Nellcor Puritan Bennett 840 ventilator system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Counseling for Primary Care Office-based Buprenorphine
Status: COMPLETED
Conditions: Opiate Dependence
Interventions: BEHAVIORAL: Manual-guided Physician Management (PM)|BEHAVIORAL: Physician Management (PM) combined with on-site manual-guided Cognitive Behavioral Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Coronary De-novo Stenosis by a Sirolimus Coated Balloon or a Paclitaxel Coated Balloon Catheter Malaysia
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: PCB PTCA|DEVICE: SCB PTCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Low-dose Aspirin Therapy in Patients With Ischemic Stroke and Microbleeds
Status: UNKNOWN
Conditions: Ischemic Stroke
Interventions: DRUG: low-dose aspirin|DRUG: conventional-does aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Effects of Autologous Adipose-Derived Stromal Cells Delivered Into Patients With Multiple Sclerosis
Status: WITHDRAWN
Conditions: Multiple Sclerosis|Autoimmune Diseases|Autoimmune Diseases of the Nervous System|Nervous System Diseases
Interventions: PROCEDURE: Harvesting and Implantation of SVF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Toripalimab Combined With S1 and Albumin Paclitaxel in Patients With Advanced Biliary Tract Cancer
Status: UNKNOWN
Conditions: Advanced Biliary Tract Cancer
Interventions: DRUG: Toripalimab Combined With S1 and Albumin Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel-Carboplatin Alone or With M2ES for Non-Small-Cell Lung Cancer
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: pegylated endostatin and Paclitaxel-Carboplatin|DRUG: Placebo and Paclitaxel-Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FLOAT Through Anxiety: Virtual Reality Application's Efficacy as a Tool to Distract From Negative Emotions and Thoughts
Status: COMPLETED
Conditions: Control|Experimental
Interventions: BEHAVIORAL: psychoeducation on emotional regulation and distraction strategy|DEVICE: Using the FLOAT app on a virtual reality device|BEHAVIORAL: psychoeducation on emotional regulation and distraction strategy + Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Listening to Qur'an Recital on Quality of Life in Systemic Lupus Erythematosus Patients
Status: RECRUITING
Conditions: Quality of Life
Interventions: OTHER: Listening to Qur'an Recital
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Common Elements Treatment Approach HIV Alcohol Reduction Trial in Zambia
Status: RECRUITING
Conditions: HIV/AIDS|Alcohol-Related Disorders|Mental Illness
Interventions: BEHAVIORAL: Alcohol Brief Intervention|BEHAVIORAL: Common Elements Treatment Approach|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Neuroprotective Strategy for Ischemic Stroke With Poor Recanalization After Thrombectomy by Intra-arterial TNK (INSIST-TNK)
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: DRUG: Intra-arterial administration of tenecteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring Treatments for Children's Abdominal Pain: Comparing Trimebutine and Probiotics
Status: RECRUITING
Conditions: Functional Abdominal Pain Syndrome|Functional Gastrointestinal Disorders|Irritable Bowel Syndrome Variant of Childhood
Interventions: DRUG: Trimebutine|DIETARY_SUPPLEMENT: Lactobacillus rhamnosus|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Salvage BGD With autoSCT Consolidation in Advanced Classical HL Patients Not Responding to ABVD
Status: ACTIVE_NOT_RECRUITING
Conditions: Hodgkin's Lymphoma
Interventions: DRUG: Bendamustine|DRUG: Gemcitabine|DRUG: Dexamethasone|DIAGNOSTIC_TEST: PET/CT|PROCEDURE: Autologous Stem Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention Trial: Immune-tolerance With Alum-GAD (Diamyd) and Vitamin D3 to Children With Multiple Islet Autoantibodies
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 1|Prediabetic State
Interventions: DRUG: Alum-GAD|DRUG: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Docetaxel, Oxaliplatin and 5-FU for Gastric Cancer With Inoperable Malignant Bowel Obstruction
Status: RECRUITING
Conditions: Metastatic Gastric Adenocarcinoma|Metastatic Gastroesophageal Junction Adenocarcinoma|Peritoneal Carcinomatosis
Interventions: DRUG: Docetaxel|DRUG: Oxaliplatin|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Coregistered CT-PET Imaging in Determining Tumor Volume and Atelectasis in Patients With Operable Non-Small-Cell Lung Cancer and Tumor Associated Atelectasis
Status: UNKNOWN
Conditions: Carcinoma, Non Small Cell Lung
Interventions: PROCEDURE: CT-scan, PET-scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Expiratory Positive Pressure on Dynamic Hyperinflation and Ability to Exercise With Upper Limbs in COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DIAGNOSTIC_TEST: Endurance test for upper limbs|DIAGNOSTIC_TEST: Functional test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breathing Exercises Effects on Forward Head Posture
Status: COMPLETED
Conditions: Forward Head Posture
Interventions: OTHER: Diaphragmatic Breathing Exercise Group|OTHER: Thoracic Extension Exercise Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of ChimeriVax™ Japanese Encephalitis Vaccine in Thai Toddlers and Children
Status: COMPLETED
Conditions: Japanese Encephalitis|Hepatitis A
Interventions: BIOLOGICAL: Japanese encephalitis vaccine (Day 0) Hepatitis A vaccine (Day 28)|BIOLOGICAL: Hepatitis A vaccine (Day 0) Japanese encephalitis vaccine (Day 28)|BIOLOGICAL: Japanese encephalitis vaccine (Day 0) Hepatitis A vaccine (Day 28)|BIOLOGICAL: Hepatitis A vaccine (Day 0) Japanese encephalitis vaccine (Day 28)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Immunoassay and Regulation of Traditional Chinese Medicine on Cancer Patients
Status: RECRUITING
Conditions: Breast Cancer|Colorectal Cancer|Cancer of Ovary|Cancer of Endometrium
Interventions: OTHER: Cases for patients diagnosed with breast cancer, colonrectal cancer, ovarian cancer and endometrial cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Virtual Reality in Hemodialysis to Improve Psychological Well-being
Status: NOT_YET_RECRUITING
Conditions: End Stage Kidney Disease|Depressive Symptoms
Interventions: BEHAVIORAL: Joviality(TM)|OTHER: Inert Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Study of GM-60106 in Healthy Adults and Otherwise Healthy Adults With an Increased Body Mass Index and Markers of Non-Alcoholic Fatty Liver Disease
Status: UNKNOWN
Conditions: Non-alcoholic Steatohepatitis
Interventions: DRUG: GM-60106|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Risk Reduction for Alzheimer's Disease
Status: COMPLETED
Conditions: Cognitively Normal Older Adults|Hypertension|Subjective Cognitive Decline|Family History of Alzheimer's Disease
Interventions: DRUG: Angiotensin II receptor blocker (ARB, losartan) and calcium channel blocker (CCB, amlodipine)|BEHAVIORAL: Aerobic Exercise Training|OTHER: Usual Care|BEHAVIORAL: Stretching Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Linear Programming Approach to Develop Local Specific Food-based Complementary Feeding Recommendation
Status: UNKNOWN
Conditions: Stunting|Anemia|Complementary Feeding Recommendation|Linear Programming|Indonesia|Infant and Young Children|Problem Nutrients
Interventions: BEHAVIORAL: Enhanced NE|BEHAVIORAL: Standard NE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Influenza Vaccine (Surface Antigen, Inactivated) Ph.Eur, Formulation 2010/2011, When Administered to Adult and Elderly Subjects
Status: COMPLETED
Conditions: Seasonal Influenza
Interventions: BIOLOGICAL: Influenza Vaccine (Surface Antigen, Inactivated) Ph.Eur, Formulation 2010/2011
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Treatment of Obsessive-Compulsive Symptoms in Youth With Prader-Willi Syndrome: A Pilot Project
Status: COMPLETED
Conditions: Prader Willi Syndrome|Obsessive-compulsive Disorder
Interventions: BEHAVIORAL: Cognitive-behavioral therapy|BEHAVIORAL: Wait-list control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of NL-Prow Interspinous Spacer to Treat Lumbar Spinal Stenosis
Status: UNKNOWN
Conditions: Lumbar Spinal Stenosis
Interventions: DEVICE: NL-Prow interspinous spacer implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peer Supported Collaborative Care Mental Health and Substance Use Disorder Care
Status: RECRUITING
Conditions: HIV Infections|Substance Use Disorders|Mental Health Disorder|Addiction|Opioid Use|Drug Use
Interventions: BEHAVIORAL: Collaborative Care Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Testing Interventions for Mobility Through Exercise (TIME)
Status: RECRUITING
Conditions: Walking, Difficulty|Mobility Limitation
Interventions: BEHAVIORAL: FAST (Functional Activity Strength Training)|BEHAVIORAL: Band Together|BEHAVIORAL: Behavioral Change Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Doxycycline on Persistent Symptoms Post-neuroborreliosis
Status: COMPLETED
Conditions: Fatigue|Radicular Pain|Cognitive Dysfunction|Paresthesia|Paresis
Interventions: DRUG: Doxycycline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Evaluation of the Biomechanical Properties of the Thoracic Aorta Coupling Magnetic Resonance Imaging and In-vitro Elasticity Tests in Patients With Ascending Aortic Aneurysm
Status: RECRUITING
Conditions: Patient With Ascending Aortic Aneurysm With Surgical Indication for Replacement
Interventions: PROCEDURE: Cardiac MRI|OTHER: in-vitro elasticity tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BMS-247550 in Treating Patients With Stage IV Melanoma
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage IV Melanoma
Interventions: DRUG: ixabepilone|OTHER: pharmacogenomic studies|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bipolar Androgen Therapy + Carboplatin in mCRPC
Status: RECRUITING
Conditions: Castration-resistant Prostate Cancer|Homologous Recombination Deficiency
Interventions: DRUG: Testosterone Enanthate 100 MG/ML Injectable Solution|DRUG: Testosterone Enanthate 100 MG/ML Injectable Solution / Carboplatin AUC 5
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Study to Evaluate the Adjustment Function of a Modified Spatz3 Adjustable Balloon (Spatz4)
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: DEVICE: Spatz4 Adjustable Balloon System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of a Novel Vaginal Delivery System for Testosterone and Dehydroepiandrosterone (DHEA)
Status: COMPLETED
Conditions: Pharmacokinetics|Hormone Deficiency
Interventions: DRUG: Dehydroepiandrosterone 2.2 g|DRUG: Dehydroepiandrosterone 1.5 g/Testosterone 25 mg|DRUG: Testosterone|DRUG: Testosterone Topical Gel|DRUG: Dehydroepiandrosterone Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating the Effect of Digesta-Lac in Healthy Adults With Occasional Constipation
Status: COMPLETED
Conditions: Occasional Constipation
Interventions: DIETARY_SUPPLEMENT: Digesta Lac|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Muscle Weakness Duration After Single Botulinum Toxin Injection in Masseter
Status: COMPLETED
Conditions: Bite Force|Botulinum Toxins, Type A
Interventions: DRUG: Botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility, Safety and Effectiveness of Chromotubation on the Remaining Fallopian Tube After a Laparoscopic Salpingectomy Due to Tubal Pregnancy
Status: NOT_YET_RECRUITING
Conditions: Ectopic Pregnancy
Interventions: PROCEDURE: performing chromotubation during the laparoscopy in order to assess the tubal patency of the remaining fallopian tube
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Kinesio-taping for the Prevention of Painful Shoulder and for the Functional Recovery of Upper Limb After Stroke
Status: COMPLETED
Conditions: Stroke, Rehabilitation
Interventions: DEVICE: Kinesio Tape Group|DEVICE: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Education Intervention in Patients With Rash Due to Epidermal Growth Factor Receptor (EGFR) Treatment.
Status: UNKNOWN
Conditions: Consent Form|Lung Cancer|Colon Cancer|Pancreas Cancer|Head and Neck Cancer|Breast Cancer
Interventions: OTHER: EDUCATION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Physical Activity for Improving Quality of Life in Prostate Cancer Patients on Androgen Deprivation Therapy (ADT)
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: walking exercise|BEHAVIORAL: weight training|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Frequency of Hypoglycemia in Patients With Type 2 Diabetes Under Insulin Therapy Older Than 75 Years in Real Life
Status: TERMINATED
Conditions: Type2 Diabetes|Elderly|Hypoglycemia
Interventions: DEVICE: glycemic sensor FREESTYLE Libre Pro
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dose Ranging Study to Compare the Efficacy and Safety of Methotrexate in Plaque Type Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of TAK-715 in Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: TAK-715 and methotrexate|DRUG: TAK-715 and methotrexate|DRUG: TAK-715 and methotrexate|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous vs Liposomal Bupivacaine Interscalene Block for Proximal Humeral Fracture (CLIP)
Status: RECRUITING
Conditions: Shoulder Fractures
Interventions: DRUG: Liposomal bupivacaine|DRUG: Standard bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Evaluating the Efficacy and Safety of Patiromer in Chinese Subjects
Status: RECRUITING
Conditions: Hyperkalemia|Renal Insufficiency, Chronic
Interventions: DRUG: Patiromer Powder for Oral Suspension (Part A)|DRUG: Placebo (Part B)|DRUG: Patiromer Powder for Orals Suspension (Part B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: My ESSENCE - A Research Study on Mindfulness for African-Americans With Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes|Sleep|Stress
Interventions: BEHAVIORAL: Mindfunlness Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Endoscopic Multispectral Imaging for the Early Detection of Barrett's Neoplasia
Status: COMPLETED
Conditions: Barrett's Esophagus|Intraepithelial Neoplasia
Interventions: DRUG: proflavine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Early Sodium Intake in Preterm Newborns
Status: COMPLETED
Conditions: Hyponatremia|Premature
Interventions: DRUG: Sodium < 1mEq/kg/day|DRUG: Sodium 5mEq/kg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Engagement of American Indians of Southwestern Tribal Nations in Cancer Genome Sequencing
Status: RECRUITING
Conditions: Malignant Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Return of Results|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Assess the Efficacy and Safety of ASC-01 in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: ASC-01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperthermia and Mitomycin C, Bacillus Calmette-Guerin, or Standard Therapy as Second-Line Therapy in Treating Patients With Recurrent Bladder Cancer
Status: UNKNOWN
Conditions: Bladder Cancer
Interventions: BIOLOGICAL: BCG solution|BIOLOGICAL: recombinant interferon alfa|DRUG: epirubicin hydrochloride|DRUG: mitomycin C|OTHER: laboratory biomarker analysis|PROCEDURE: hyperthermia treatment|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Food Effect on the Pharmacokinetics of Nifurtimox Tablets in Chronic Chagas' Patients
Status: COMPLETED
Conditions: Chagas Disease
Interventions: DRUG: Nifurtimox (BAYa2502)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of STAHIST in Seasonal Allergic Rhinitis (SAR) Subjects
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Placebo|DRUG: STAHIST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Non-inferiority Study With Two Treatment Arms Eszopiclone 3 mg Versus Zopiclone 7.5 mg - for the Treatment of Insomnia
Status: COMPLETED
Conditions: INSOMNIA
Interventions: DRUG: Eszopiclone|DRUG: Zopiclone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tacrolimus Sustained-release Capsules in Induction Phase Treatment in Lupus Nephritis
Status: WITHDRAWN
Conditions: Lupus Nephritis
Interventions: DRUG: ADVAGRAF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GBV, Primary Trauma & Trauma Resilience & Understanding Self-help Therapy Utilization in Uganda
Status: COMPLETED
Conditions: Domestic Violence|Psychological Distress|Post-Traumatic Stress Disorder|Suicidality
Interventions: BEHAVIORAL: Trauma Resilience & Understanding Self-help Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Inflammatory, Functional and Image Composite Measure to Define Asthma Control
Status: UNKNOWN
Conditions: Asthma
Interventions: DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Usability of Pericardial Flushing With the Haermonics Pure System After Cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: Surgical Blood Loss|Surgical Complication
Interventions: DEVICE: Haermonics Pure system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Immunogenicity Study of Recombinant Human C1 Inhibitor for the Treatment of Acute HAE Attacks
Status: COMPLETED
Conditions: Hereditary Angioedema
Interventions: DRUG: rhC1INH|DRUG: Placebo (Saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Video Interventions for Depression
Status: COMPLETED
Conditions: Depressive Symptoms
Interventions: BEHAVIORAL: Entrée: Cognitive skills|BEHAVIORAL: Entrée: Behavioral skills|BEHAVIORAL: Entrée: Interpersonal skills|BEHAVIORAL: Sampler skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and GEM 231 in Treating Patients With Recurrent or Refractory Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: GEM 231|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Imipenem/Relebactam/Cilastatin Versus Piperacillin/Tazobactam for Treatment of Participants With Bacterial Pneumonia (MK-7655A-014)
Status: COMPLETED
Conditions: Bacterial Pneumonia
Interventions: DRUG: Imipenem|DRUG: Relebactam|DRUG: Cilastatin|DRUG: Piperacillin|DRUG: Tazobactam|DRUG: Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ultrasound on Orthodontic Tooth Movement
Status: COMPLETED
Conditions: Malocclusion
Interventions: DEVICE: Ultrasound|DEVICE: Sham comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind Placebo-Control Dose Escalating Study to Evaluate the Safety and Immunogenicity of dmLT by Oral, Sublingual and Intradermal Vaccination in Adults Residing in an Endemic Area
Status: TERMINATED
Conditions: Gastroenteritis Escherichia Coli|Immunisation
Interventions: OTHER: Placebo|OTHER: Placebo|OTHER: Placebo|BIOLOGICAL: Recombinant Double Mutant Heat-Labile Toxin LT(R192G/L211A) (dmLT) Oral enterotoxigenic Escherichia coli (ETEC) Vaccine|BIOLOGICAL: Recombinant Double Mutant Heat-Labile Toxin LT(R192G/L211A) (dmLT) Oral enterotoxigenic Escherichia coli (ETEC) Vaccine|BIOLOGICAL: Recombinant Double Mutant Heat-Labile Toxin LT(R192G/L211A) (dmLT) Oral enterotoxigenic Escherichia coli (ETEC) Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Supercapsular Percutaneously Assisted Total Hip Approach for the Elderly With Femoral Neck Fractures
Status: UNKNOWN
Conditions: Femoral Neck Fractures
Interventions: PROCEDURE: Experimental group|PROCEDURE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Apatinib and 5-Fu Combination Regimen to Treat Advanced Colorectal Cancer Patients
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Apatinib|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Targeting of Anti-hk2 Antibody in mCRPC
Status: TERMINATED
Conditions: Castration-Resistant Prostatic Cancer|Metastatic Disease
Interventions: DRUG: 111In-DOTA-h11B6
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation Contact X-ray Brachytherapy for Rectal Preservation in Intermediate Substage Rectal Adenocarcinoma
Status: RECRUITING
Conditions: Adult With Intermediate Low or Mid Rectal Adenocarcinoma
Interventions: RADIATION: contact X-ray brachytherapy (CXB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Assess Change in Upper Airway Geometry Between Upright and Supine Position
Status: COMPLETED
Conditions: Changes in Upper Airway Geometry
Interventions: RADIATION: Cone Beam Computed Tomography|RADIATION: High Resolution Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Platelet Rich Plasma Injection for Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis|Cartilage Degeneration
Interventions: BIOLOGICAL: PRP|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tadalafil for Treatment of Priapism in Men With Sickle Cell Anemia
Status: WITHDRAWN
Conditions: Sickle Cell Anemia|Priapism
Interventions: DRUG: tadalafil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ablation of Consecutive Atrial Tachycardia
Status: RECRUITING
Conditions: Heart Arrhythmia|Heart Diseases|Arrhythmias, Cardiac|Atrial Tachycardia
Interventions: PROCEDURE: Catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerability and Efficacy of Tremelimumab in Combination With Gefitinib in NSCLC Patients
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Gefitinib|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Gene Transfer Therapy Study to Evaluate the Safety of Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD)
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: GENETIC: delandistrogene moxeparvovec
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Evaluate Safety, Tolerability, and Performance of the FAST PV Technology™ in Chronic Dialysis Patients
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DEVICE: VFI using the FAST PV Technology
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Investigate the Safety of SYHA1815 in Subjects With Unresectable Locally Advanced or Metastatic Solid Tumors
Status: UNKNOWN
Conditions: Locally Advanced Unresectable Carcinoma
Interventions: DRUG: SYHA1815
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study of STA-9090 and Docetaxel in Patients With Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor Malignancies
Interventions: DRUG: STA-9090 (ganetespib) with Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Astigmatism Reducing Effect With Toric IOLs in Eyeswith Low Astigmatism
Status: UNKNOWN
Conditions: Cataract|Astigmatism
Interventions: PROCEDURE: toric intraocular lens|PROCEDURE: non toric intraocular lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Constraint Induced Movement Therapy With And Without Cross Education In Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: Group A: mCIMT with cross-education|OTHER: Group B: mCIMT without cross-education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation and CD4 Count in HIV-Infected Children
Status: COMPLETED
Conditions: HIV
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DRUG: No supplementation|DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of the "Hypotension Probability Index" on Intraoperative and Postoperative Hypotension in ENT- and OM-Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypotension|ENT Disease|Acute Kidney Injury|Anesthesia
Interventions: DEVICE: Hypotension probability index (HPI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation (CASCADE)
Status: COMPLETED
Conditions: Arrhythmia|Cardiovascular Diseases|Heart Arrest|Heart Diseases|Myocardial Infarction|Ventricular Fibrillation
Interventions: DRUG: amiodarone|DRUG: imipramine|DRUG: mexiletine|DRUG: procainamide|DRUG: propafenone|DRUG: quinidine|DRUG: sotalol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: Effect of Probiotics on Eradication of Persistent H.Pylori Infection
Status: NOT_YET_RECRUITING
Conditions: Persistent Helicobacter Pylori Infection
Interventions: DRUG: Bifidobacterium Infants plus Enterococcus Feacium plus Lactobacillus Acidophilus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pivotal Study of Iodine I 131 Tositumomab for Chemotherapy-refractory Low-grade or Transformed Low-grade B-cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: BIOLOGICAL: Tositumomab and Iodine I 131 Tositumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Haploidentical NK Cells After Pemetrexed in Patients With Stage IV Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Pemetrexed and donor-derived NK cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Periodontal Infection and Endothelial Dysfunction
Status: COMPLETED
Conditions: Periodontitis
Interventions: PROCEDURE: One-Stage Full-Mouth Disinfection|PROCEDURE: Periodontal care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Phase III Clinical Trial of JDP-205 IV Injection for Treatment of Acute Urticaria
Status: COMPLETED
Conditions: Acute Urticaria
Interventions: DRUG: JDP-205 Injection|DRUG: Diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conservative Treatment of Postprostatectomy Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: BEHAVIORAL: Behavioral Therapy|DEVICE: Pelvic Floor Electrical Stimulation|BEHAVIORAL: Biofeedback|OTHER: No Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Complex Phytoadaptogenes in Chronic Periodontitis Treatment.
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Cocktail from complex phytoadaptogens (CFA)|PROCEDURE: Standard non-surgical periodontal treatment (NSPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Nighttime Pruritus in Atopic Dermatitis
Status: WITHDRAWN
Conditions: Atopic Dermatitis
Interventions: DRUG: Melatonin|DRUG: Diphenhydramine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quantifying the Benefits of Supervised vs. Unsupervised Pre-habilitation for Patients With Acute ACL Tears
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Rupture|Anterior Cruciate Ligament Tear|Anterior Cruciate Ligament Injuries
Interventions: OTHER: Self-guided pre-habilitation exercise program|OTHER: Traditional pre-habilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Tap Block Technique Via the Anterior Approach in Elective Surgery of the Spine
Status: COMPLETED
Conditions: Elective Surgery of the Spine by Laparotomy
Interventions: DRUG: Ropivacaine 0.2%|DRUG: Chlorure de sodium 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Bioequivalence Study of Two Formulations With the Association of Tenofovir 300 mg and Emtricitabine 200 mg.
Status: COMPLETED
Conditions: Acquired Immunodeficiency Syndrome
Interventions: DRUG: Tenofovir disoproxil fumarate and emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Multi-centre Clinical Trial on Hormone Replacement Treatment in China
Status: UNKNOWN
Conditions: Menopausal Syndrome|Cardiovascular Disease|Osteoporosis|Breast Cancer
Interventions: DRUG: estradiol plus MPA|DRUG: Ximingting Tablet|DRUG: estradiol plus progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vebreltinib Plus PLB1004 in EGFR-mutated, Advanced NSCLC With MET Amplification or MET Overexpression Following EGFR-TKI
Status: RECRUITING
Conditions: Non-Small-Cell Lung Cancer
Interventions: DRUG: Vebreltinib|DRUG: PLB1004
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Efficacy and Safety of Umeclidinium/Vilanterol and Fluticasone Propionate/Salmeterol in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Umeclidinium/vilanterol|DRUG: Fluticasone propionate/salmeterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Anti-Viral Prophylaxis for HBsAg(+) or HBcAb(+)/HBsAb(-) Patients Starting Anti-TNFα
Status: TERMINATED
Conditions: Chronic Hepatitis B|Rheumatoid Arthritis|Ankylosing Spondylitis|Psoriatic Arthritis|Juvenile Idiopathic Arthritis
Interventions: DRUG: Entecavir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Examination of Whether Host Preconditioning Modifies Short-term Transplant Survival
Status: WITHDRAWN
Conditions: Atopic Dermatitis|Eczema
Interventions: DRUG: Pre-Treatment with Dial liquid antibacterial soap|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Using the Ending Self-Stigma Intervention to Reduce Internalized Stigma Among People Living With HIV Who Use Substances
Status: ENROLLING_BY_INVITATION
Conditions: HIV|Opioid Use|Cocaine Use|Stigma, Social
Interventions: BEHAVIORAL: Ending Self Stigma for Persons living with HIV and Use Substances
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pressure Ulcer Multi-disciplinary Teams Via Telemedicine (PUMTT): A Trial in Long Term Care
Status: COMPLETED
Conditions: Pressure Ulcers|Multi-disciplinary Wound Care Teams|Remote Support|Digital Wound Photography
Interventions: OTHER: Exposure to multi-disciplinary wound care team
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Lovaza on High Density Lipoprotein (HDL) Composition and Function in Hypertriglyceridemia
Status: WITHDRAWN
Conditions: Hypertriglyceridemia
Interventions: DRUG: Lovaza (Omega-3 acid ethyl esters)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of the Bladder EpiCheck for Detection of Recurrent Urothelial Cell Carcinoma
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DEVICE: Bladder EpiCheck Urine Test|PROCEDURE: Cystoscopy and pathology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: High Volume Caudal Study
Status: COMPLETED
Conditions: Male Circumcision
Interventions: DRUG: High Volume-Low Concentration without Clonidine|DRUG: High Volume-Low Concentration with clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determination of the ED50 and ED95 of Prophylactic Norepinephrine Infusion for Preventing Post-induction Hypotension in Elderly Patients Undergoing Major Abdominal Surgery
Status: RECRUITING
Conditions: Norepinephrine|Post-induction Hypotension
Interventions: DRUG: norepinephrine bitartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The FARAPULSE FARA-Freedom Trial A Prospective Open Label Single Arm Post Market Clinical Follow-Up Trial of the FARAPULSE Pulsed Field Ablation System in Patients With Paroxysmal Atrial Fibrillation
Status: ACTIVE_NOT_RECRUITING
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: FARAPULSE Pulsed Field Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-finding Study of LIK066 Compared With Placebo or Sitagliptin to Evaluate Change in HbA1c in Patients With Diabetes
Status: WITHDRAWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: LIK066|DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Functional Strength Training Speeds on Executive Functions in 6-12-Year-Old Children.
Status: NOT_YET_RECRUITING
Conditions: Strength Training|Executive Function|Child
Interventions: OTHER: Strength training at high and low speeds.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive, Emotional, and Neural Responses to Acute Inflammation
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Typhoid Vi Polysaccharide Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: #StayHome: Early Hydroxychloroquine to Reduce Secondary Hospitalisation and Household Transmission in COVID-19
Status: SUSPENDED
Conditions: COVID-19
Interventions: DRUG: Hydroxychloroquine|DRUG: Mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT