pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of Fibrinogen Concentrate and Cryoprecipitate in Pediatric Cardiac Surgery Patients
Status: COMPLETED
Conditions: Pediatric HD|Bleeding
Interventions: DRUG: Fibrinogen|DRUG: Cryoprecipitate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determine the ED50 of Dexmedetomidine to Facilitate LMA Insertion During Anaesthesia Induction
Status: UNKNOWN
Conditions: Anesthesia
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Pressure Ulcers in Patients Under Non-Invasive Mechanical Ventilation
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: DEVICE: Allevyn Thin®|DEVICE: Askina Transorbent Border®|DEVICE: Linovera®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Immune and Cognitive Benefits of Mango Intake in Young Adults
Status: NOT_YET_RECRUITING
Conditions: Cognition|Immunity
Interventions: DIETARY_SUPPLEMENT: Mango group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 1/2 Study of TU2218 Alone and in Combination With Checkpoint Inhibitors in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: TU2218|DRUG: Anti-PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ATG-010 in Combination With ATG-008 in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma
Status: TERMINATED
Conditions: Relapsed/Refractory Diffuse Large B-cell Lymphoma
Interventions: COMBINATION_PRODUCT: ATG-010 and ATG-008
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Pembrolizumab (MK-3475) With or Without Maintenance Olaparib in First-line Metastatic Squamous Non-small Cell Lung Cancer (NSCLC, MK-7339-008/KEYLYNK-008)
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Squamous Cell, Non-small-cell Lung
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Nab-paclitaxel|DRUG: Olaparib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Safety and Immunogenicity Study of aQIV in Elderly Adults
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: MF59-adjuvanted Quadrivalent Subunit Inactivated Egg-derived Influenza Vaccine (aQIV)|BIOLOGICAL: Licensed MF59-adjuvanted Trivalent Subunit Inactivated Egg-derived Influenza Vaccine (aTIV-1)|BIOLOGICAL: MF59-adjuvanted Trivalent Subunit Inactivated Egg-derived Influenza Vaccine Containing the Alternate B Strain (aTIV-2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Enavogliflozin on Recurrence of Atrial Fibrillation After Catheter Ablation
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: Enavogliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Dose of WIN-1001X by Evaluating Efficacy and Safety in Early Parkinson's Disease Patients
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DRUG: WIN-1001X|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Restoring Untreated and SDF-treated Dentine Caries Lesions in Primary Teeth of Preschool Children
Status: UNKNOWN
Conditions: Dental Restoration Failure of Marginal Integrity
Interventions: DEVICE: application of 38% silver diamine fluoride solution|OTHER: application of a placebo (tonic water)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Perinatal Outcomes Using Conditional and Targeted Transfers
Status: ACTIVE_NOT_RECRUITING
Conditions: Utilization, Health Care|Birth Outcomes
Interventions: BEHAVIORAL: Conditional cash transfer|BEHAVIORAL: Risk information provision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Supporting Decisions With Transcranial Direct Current Stimulation in Healthy Young and Elderly Individuals
Status: COMPLETED
Conditions: Real tDCS|Sham tDCS
Interventions: DEVICE: real anodal transcranial direct current stimulation|DEVICE: sham transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Japan Long-term Safety for Tiotropium Plus Olodaterol
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium + Olodaterol|DEVICE: Respimat|DRUG: Tiotropium + Olodaterol|DRUG: Olodaterol|DEVICE: Respimat|DEVICE: Respimat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Danzhu Fuyuan Granule as Adjunctive Therapy for Chronic Stable Angina, Vascular Dementia and Idiopathic Membranous Nephropathy: A Bayesian Basket Trial
Status: UNKNOWN
Conditions: Chronic Stable Angina|Vascular Dementia|Idiopathic Membranous Nephropathy
Interventions: DRUG: Danzhu Fuyuan Granule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterisation of T-cell Response to Keyhole Limpet Hemocyanin (KLH) and Tuberculin Purified Protein Derivative (PPD)
Status: COMPLETED
Conditions: Dermatitis
Interventions: OTHER: KLH 0.1 mg|OTHER: KLH 5 mg|OTHER: PBS (0.1 mL)|OTHER: Tuberculin PPD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of Acute Ketone Monoester Supplementation on 20-Minute Time-Trial Performance in Trained Cyclists
Status: COMPLETED
Conditions: Exercise|Ketosis
Interventions: DIETARY_SUPPLEMENT: Ketone monoester|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of AMN107 in Patients With GastroIntestinal Stromal Tumors (GIST) Who Have Failed Both Imatinib and Sunitinib
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: AMN107
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety and Efficacy of Ticagrelor (AZD6140) Versus Clopidogrel in Asian/Japanese Patients With Non-ST or ST Elevation Acute Coronary Syndromes (ACS)
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Percutaneous Coronary Intervention
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel|DRUG: Acetylsalicylic acid ASA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Explore the Renal Safety of Visipaque Injection 320 mgI/mL in Patients With Chronic Kidney Disease
Status: TERMINATED
Conditions: Chronic Kidney Diseases
Interventions: DRUG: Visipaque|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Schema Therapy vs. Cognitive Behavioral Therapy vs. Individual Supportive Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: schema therapy|BEHAVIORAL: cognitive behavioral therapy|BEHAVIORAL: individualized supportive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: mWELLCARE:An Integrated mHealth System for the Prevention and Care of Chronic Disease
Status: COMPLETED
Conditions: Hypertension|Diabetes|Depression|Alcohol Use Disorder
Interventions: OTHER: mWELLCARE|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Radiomics Multifactorial Biomarker for Pulmonary Nodules
Status: COMPLETED
Conditions: Lung Neoplasms|Carcinoma, Non-Small-Cell Lung|Lung Diseases|Neoplasms|Pathology
Interventions: DIAGNOSTIC_TEST: radiomics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Postprandial Inflammation and Fatty Acids
Status: COMPLETED
Conditions: Cardiovascular Disease|Diabetes Type 2|Obesity
Interventions: OTHER: High saturated fat shake|OTHER: High monounsaturated fat shake|OTHER: High polyunsaturated fat shake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Clazakizumab in Highly-HLA Sensitized Patients Awaiting Renal Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Failure, Chronic|End-Stage Renal Disease|Transplant Glomerulopathy|Transplant;Failure,Kidney|Kidney Transplant Failure and Rejection|Antibody-mediated Rejection|Kidney Transplant; Complications
Interventions: DRUG: Clazakizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Early Diagnosis and Treatment of OSA on Hospital Readmission in Hospitalized COPD Patients
Status: NOT_YET_RECRUITING
Conditions: Obstructive Sleep Apnea|Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRgFUS Versus EBRT in Patients With Metastatic Non-spinal Bone Disease
Status: COMPLETED
Conditions: Secondary Bone Cancer|Bone Metastases
Interventions: PROCEDURE: Bone Metastases Pain treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess Safety and Efficacy of VAD044 in HHT Patients
Status: RECRUITING
Conditions: Hereditary Hemorrhagic Telangiectasia (HHT)
Interventions: DRUG: VAD044
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Placebo Controlled Study of the Safety, Activity and Pharmacokinetics of HQK-1001 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HQK-1001|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CBP501/Cisplatin/Nivolumab Combinations in Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer Stage IV
Interventions: DRUG: CBP501 (16)|DRUG: CBP501 (25)|DRUG: Cisplatin|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improved Novel VaccIne CombinaTion InflUenza Study
Status: TERMINATED
Conditions: Influenza
Interventions: DRUG: Seasonal influenza vaccine|DRUG: MVA-NP+M1|DRUG: Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of Insulin Degludec/Insulin Aspart Biosimilar (22011) Compared With Insulin Degludec/Insulin Aspart(Ryzodeg) in Participants With Type 2 Diabetes in China
Status: NOT_YET_RECRUITING
Conditions: Diabetes
Interventions: DRUG: Insulin Degludec and Insulin Aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Study of Safety and Efficacy of WelChol® as an Additional Therapy in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Colesevelam hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HTX-011 in Spinal Surgery
Status: COMPLETED
Conditions: Post-Operative Pain|Lumbar Laminectomy
Interventions: DRUG: Bupivacaine HCI without epinephrine|DRUG: HTX-011|DEVICE: Luer Lock Applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Family Integrated Care on Preparing Parents With Premature Infants Hospitalized in the Neonatal Intensive Care Unit for Discharge
Status: COMPLETED
Conditions: Neonatal Intensive Care Unit|Parents
Interventions: OTHER: Supporting parents who have premature babies to be ready for discharge with the training given within the scope of FICare model.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oral Care to Prevent Ventilator-associated Pneumonia
Status: COMPLETED
Conditions: Oral Hygiene, Oral Health|Ventilators, Mechanical
Interventions: COMBINATION_PRODUCT: One group received standard oral care.|COMBINATION_PRODUCT: It was applied to the other group by aspiration.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fixed Duration Pirtobrutinib and Obinutuzumab in Chronic Lymphocytic Leukemia
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Pirtobrutinib|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mindfulness Based Stress Reduction in Patients With Painful Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetes Mellitus|Type I Diabetes|Type II Diabetes|Diabetic Peripheral Neuropathy|Chronic Pain
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Autologous Peripheral Blood Stem Cell Transplant Followed by Donor Bone Marrow Transplant in Treating Patients With High-Risk Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Multiple Myeloma, or Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: B-Cell Prolymphocytic Leukemia|Hypodiploidy|Loss of Chromosome 17p|Plasma Cell Leukemia|Progression of Multiple Myeloma or Plasma Cell Leukemia|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Non-Hodgkin Lymphoma|Recurrent Childhood Hodgkin Lymphoma|Recurrent Childhood Non-Hodgkin Lymphoma|Recurrent Chronic Lymphocytic Leukemia|Recurrent Plasma Cell Myeloma|Recurrent Small Lymphocytic Lymphoma|Refractory Childhood Hodgkin Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Non-Hodgkin Lymphoma|Refractory Plasma Cell Myeloma|Refractory Small Lymphocytic Lymphoma|t(14;16)|t(4;14)|T-Cell Prolymphocytic Leukemia|Waldenstrom Macroglobulinemia
Interventions: PROCEDURE: Allogeneic Bone Marrow Transplantation|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|PROCEDURE: Autologous-Allogeneic Tandem Hematopoietic Stem Cell Transplantation|DRUG: Carmustine|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Etoposide|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan|DRUG: Mycophenolate Mofetil|PROCEDURE: Peripheral Blood Stem Cell Transplantation|DRUG: Tacrolimus|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Vinorelbine or Capecitabine Combined With Trastuzumab as Adjuvant Treatment for Patients With Lymph Node Negative, HER-2 Positive and Small Tumor Size Breast Cancer (ORCHID)
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Vinorelbine|DRUG: Capecitabine|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-CD19 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Refractory Non-Hodgkin Lymphoma|Burkitt Lymphoma|Mantle Cell Lymphoma|Follicular Lymphoma|Lymphoplasmacytic Lymphoma|Primary Mediastinal Large B Cell Lymphoma|Diffuse Large B Cell Lymphoma|Small Lymphocytic Lymphoma|Transformed Lymphoma
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|BIOLOGICAL: anti-CD19 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Dexamethasone Versus Laser Photocoagulation in Participants With Diabetic Macular Edema
Status: COMPLETED
Conditions: Macular Edema
Interventions: DRUG: Dexamethasone|PROCEDURE: Laser Photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Characteristics, Treatment Patterns and Outcomes of Patients Enrolled in the Tezepelumab Patient Access Programme; a Retrospective, Observational Medical Chart Review Conducted in UK Severe Asthma Centres
Status: RECRUITING
Conditions: Severe Asthma
Interventions: DRUG: Tezepelumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ovulation Induction With Clomiphene Citrate and Dexamethasone
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: Placebo|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter, Randomized, Double-Blind, Double-Dummy, Phase 3 Study of the Safety and Efficacy of Elvitegravir Versus Raltegravir
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Elvitegravir|DRUG: Raltegravir|DRUG: EVG placebo|DRUG: RAL placebo|DRUG: Background regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety and Effectiveness of Elafibranor in Adult Participants With Primary Sclerosing Cholangitis.
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Sclerosing Cholangitis
Interventions: DRUG: Elafibranor 80 mg|DRUG: Elafibranor 120 mg|DRUG: Placebo Matched to Elafibranor 80 mg|DRUG: Placebo Matched to Elafibranor 120 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Anaesthetic Gases in Maintainance of General Anaesthesia in Paediatrics
Status: COMPLETED
Conditions: Paediatrics|General Anaesthesia
Interventions: DRUG: DESFLURANE AND SEVOFLURANE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Examining the Efficacy of Acceptance and Commitment Therapy (ACT) Microinterventions for Distressed First-Generation College Students
Status: COMPLETED
Conditions: Psychological Distress|Self-Assessment|Mood Change
Interventions: BEHAVIORAL: compACT Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ivermectina Colombia (IVERCOL)
Status: UNKNOWN
Conditions: COVID-19 Pneumonia
Interventions: DRUG: Ivermectin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Subclinical Leaflet Thrombosis and Prosthesis Type on Transcatheter Aortic Valve Degeneration (POPular PET TAVI)
Status: RECRUITING
Conditions: Aortic Valve Stenosis
Interventions: DIAGNOSTIC_TEST: 18F-sodium fluoride Positron Emission Tomography (18F-NaF PET), Cardiac Computed Tomography (CT), Transthoracic Echocardiography (TTE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ensuring Quality in Psychological Support
Status: COMPLETED
Conditions: Psychological Distress|Depression
Interventions: BEHAVIORAL: Ensuring Quality in Psychological Support|BEHAVIORAL: Standard Training and Supervision
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Using Surveys to Learn More About Treatment With Steroidal Mineralocorticoid Receptor Antagonists, How They Are Used, What Side Effects They Have, and How Satisfied People Who Receive Them Are in the US
Status: COMPLETED
Conditions: Chronic Kidney Disease|Type 2 Diabetes Mellitus|Heart Failure
Interventions: OTHER: sMRA therapies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Preoperative Oral Carbohydrates on Quality of Recovery in Laparoscopic Colorectal Surgery Patients
Status: COMPLETED
Conditions: Colorectal Disease
Interventions: DIETARY_SUPPLEMENT: carbohydrate beverage|DIETARY_SUPPLEMENT: NPO(None Per Oral)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Stereotactic Body Radiation Therapy (SBRT) in Patients With Oligoprogressive Metastatic Cancers of the Breast and Lung
Status: ACTIVE_NOT_RECRUITING
Conditions: TNBC - Triple-Negative Breast Cancer|Triple Negative Breast Cancer|NSCLC|NSCLC Stage IV|Non Small Cell Lung Cancer|Non Small Cell Lung Cancer Metastatic|NSCLC Stage IV Without EGFR/ALK Mutation
Interventions: RADIATION: Sterotactic Body Radiotherapy/SBRT|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Clevidipine Assessing Its Postoperative Antihypertensive Effect in Cardiac Surgery (ESCAPE-2)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: clevidipine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Augmentation of Depression Treatment by Gamified Network Retraining
Status: COMPLETED
Conditions: Depression Mild|Cognitive Impairment|Cognitive Dysfunction|Depressive Disorder|Depression
Interventions: BEHAVIORAL: Usability of the CCT|BEHAVIORAL: Changes in regards to the depressive disorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study Evaluating the Effects of Food, Cytochrome P450 Inhibition and Induction on the Pharmacokinetics of CC-122
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: CC-122|DRUG: Itraconazole|DRUG: Fluvoxamine|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: tDCS-Augmented Prolonged Exposure Therapy
Status: WITHDRAWN
Conditions: Posttraumatic Stress Disorder|PTSD|Anxiety|Depression
Interventions: DEVICE: Transcranial Direct Current Stimulation (tDCS)|BEHAVIORAL: Prolonged Exposure Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Use of EZCare/V1STA in the Management of Acute and Chronic Wounds
Status: COMPLETED
Conditions: Wounds
Interventions: DEVICE: EZCare/V1STA Negative Pressure Wound Therapy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tulmimetostat (CPI-0209) in Patients With Mycosis Fungoides and Sézary Syndrome
Status: RECRUITING
Conditions: Mycosis Fungoides|Sezary Syndrome|Mycosis Fungoides/Sezary Syndrome
Interventions: DRUG: Tulmimetostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visually Impaired Women Model-based Cancer Education and Breast Self-examination
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer Awareness and BSE in Visually Impaired Women
Interventions: OTHER: Training and BSE application on a model
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized Trial of Lenalidomide, Bortezomib, Dexamethasone vs High-Dose Treatment With SCT in MM Patients up to Age 65
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: Bortezomib|DRUG: Dexamethasone|PROCEDURE: Autologous Stem Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gameplay as a Source of Intrinsic Motivation in a Randomized Controlled Trial of Auditory Training for Tinnitus
Status: COMPLETED
Conditions: Tinnitus
Interventions: OTHER: reactive auditory training|OTHER: Interactive auditory training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Deep Breathing Exercise on Dyspnea, Anxiety and Quality of Life in Patients Treated for COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: BEHAVIORAL: Deep Breathing Exercise with Triflo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Using Mobile Health Technology in Colorectal Cancer Screening Uptake
Status: NOT_YET_RECRUITING
Conditions: CRC, Colorectal Cancer
Interventions: BEHAVIORAL: Assessment of screening intention and Transtheoretical Model stages for CRC screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Improving Medication Adherence in Older African Americans With Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Mild Cognitive Impairment
Interventions: BEHAVIORAL: Primary Care-Occupational Therapy|BEHAVIORAL: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Safety/Efficacy of Diagnostic Skin Test Panel and Desensitization Hormone Kit for Treatment of Premenstrual Syndrome (PMS)
Status: UNKNOWN
Conditions: Premenstrual Syndrome
Interventions: DRUG: Skin test panel and desensitization kit|DRUG: Skin test panel and solvent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Iron Balance Study of DFO and GT56-252 in Patients With Transfusional Iron Overload Secondary to Beta-Thalassemia
Status: COMPLETED
Conditions: Beta-Thalassemia
Interventions: DRUG: Deferitrin (GT56-252)|DRUG: desferoxamine (DFO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Levetiracetam on the Postmastectomy Pain Syndrome
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Levetiracetam (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Balloon Dilation in Selected Subjects With Refractory Eustachian Tube Dysfunction
Status: COMPLETED
Conditions: Eustachian Tube Dysfunction
Interventions: PROCEDURE: Balloon dilation of the Eustachian tube
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Elastic Band Resistance on Postural Stability and Physical Function in Older Adults
Status: COMPLETED
Conditions: Stability|Posturography|Balance|Old Age; Debility
Interventions: DEVICE: A repeated measures acute study using using elastic resistance bands in older adults to challenge stability.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Combined Kidney and Blood Stem Cell Transplant From a Brother or Sister Donor
Status: RECRUITING
Conditions: Renal Transplant Rejection|Tolerance|Kidney Transplant
Interventions: BIOLOGICAL: Donor CD34+ and CD3+ cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Hydrocortisone and Mannitol in Treatment of Postdural Puncture Headache
Status: COMPLETED
Conditions: Headache
Interventions: DRUG: hydrocortisone 100mg.|DRUG: mannitol 20% intravenous fluid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Using Xolair in Rush Multi Oral Immunotherapy in Multi Food Allergic Patients
Status: COMPLETED
Conditions: Food Allergy
Interventions: DRUG: Xolair|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Sitagliptin for Stress Hyperglycemia or Mild Diabetes Following Cardiac Surgery
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2|Hyperglycemia
Interventions: DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Performance and Safety of the Resorbable Collagen Membrane "Ez Cure"
Status: UNKNOWN
Conditions: Oral Bone Defect|Maxillofacial Bone Defect|Periodontal Bone Loss|Alveolar Bone Loss
Interventions: DEVICE: Guided Tissue Regeneration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stability of Dental Implants Placed in Patients With Vitamin D Deficiency Using Sequential Drilling Versus a New One Single Drilling Design
Status: COMPLETED
Conditions: Implant Stability With Vitamin D Deficiency
Interventions: PROCEDURE: sequential drilling technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of ABX-1431 on Patients With Tourette Syndrome
Status: COMPLETED
Conditions: Tourette Syndrome|Chronic Motor Tic Disorder
Interventions: DRUG: ABX-1431|DRUG: Placebo Comparator|DRUG: ABX-1431
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: THE FRENCH NATIONAL NAFLD COHORT (FRench pAtients With MEtabolic Steatosis)
Status: NOT_YET_RECRUITING
Conditions: NAFLD|NASH|NASH - Nonalcoholic Steatohepatitis|Fibrosis|Cirrhosis
Interventions: OTHER: Biological specimens|OTHER: Additional visit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Gallium Ga 68-labeled PSMA-11 PET/CT in Detecting Recurrent Prostate Cancer in Patients After Initial Therapy
Status: COMPLETED
Conditions: Prostate Adenocarcinoma|Recurrent Prostate Carcinoma
Interventions: RADIATION: Gallium Ga 68 Gozetotide|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Transdermal Administration of a Prokinetic Agent for Bowel Evacuation in Persons With SCI
Status: COMPLETED
Conditions: Spinal Cord Injury|Neurogenic Bowel
Interventions: DRUG: Neostigmine and Glycopyrrolate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pioglitazone on Left Ventricular Diastolic Function in Type 2 Diabetes Mellitus
Status: WITHDRAWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Pioglitazone (Actos)|DRUG: Anti-diabetic agent other than pioglitazone or rosiglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Pilot Study to Evaluate the Efficacy of Montelukast in the Treatment of Acute Otitis Media (AOM) in Children
Status: COMPLETED
Conditions: Acute Otitis Media|Otitis Media|Ear Infection
Interventions: DRUG: Montelukast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Modified Huang-Lian-Jie-Du Decoction (MHLJDD) for Atopic Dermatitis in Children
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: Modified Huang-Lian-Jie-Du Decoction (MHLJDD)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Lanreotide Autogel 120mg and Temozolomide in Progressive GEP-NET
Status: COMPLETED
Conditions: Gastroenteropancreatic Neuroendocrine Tumors
Interventions: DRUG: Lanreotide Autogel 120 mg|DRUG: Temozolomide (TMZ)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Dose Study to Assess the Safety, Tolerability, PK and PD Effects in Male Volunteers
Status: COMPLETED
Conditions: IBD
Interventions: DRUG: AKB-4924|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multicentre Study of MITRACLIP® Transcatheter Mitral Valve Repair in Patients With Severe Primary Mitral Regurgitation Eligible for High-risk Surgery
Status: RECRUITING
Conditions: Mitral Regurgitation
Interventions: DEVICE: percutaneous mitral valve repair with MITRACLIP NT, MITRACLIP NTR/XTR, MITRACLIP G4NT/XT, MITRACLIP G4NTW/XTW|PROCEDURE: cardiac surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Markers of Gluten Ingestion in Celiac Disease Patients
Status: COMPLETED
Conditions: Adult Form of Celiac Disease
Interventions: OTHER: Administration of gluten( food /wheat protein) capsules or placebo(cornstarch) capsules and tests for novel markers will be done at intervals.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Gelesis200 Safety and Tolerability Study and Effects on Glycemic and Appetite Parameters
Status: COMPLETED
Conditions: Healthy Overweight Obese
Interventions: DEVICE: Gelesis200|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of SY-3505 in Patients With ALK-positive NSCLC Who Have Failed Prior Second-Generation ALK TKI
Status: RECRUITING
Conditions: Non-small-cell Lung Carcinoma
Interventions: DRUG: SY-3505
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amoxicillin Susceptibility of Oral Streptococci After a 3-Day or a 7-Day Amoxicillin Therapy
Status: TERMINATED
Conditions: Odontogenic Infection
Interventions: DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oral Baclofen and Botulinum Toxin Treatments in Hemiplegic Spasticity on the Nociceptive Flexor Reflex
Status: COMPLETED
Conditions: Stroke Sequelae|Spastic Hemiplegia
Interventions: DIAGNOSTIC_TEST: Nociceptor flexor reflex|DRUG: Botox|DRUG: Baclofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of SVF-gel Filling and CO2 Fractional Laser on Atrophic Acne Scar Treatment
Status: COMPLETED
Conditions: Autologous Fat Graft Harvesting, SVF-gel Preparation and Filling|CO2 Fractional Laser Treatment by Using Acupulse Device
Interventions: DEVICE: SVF-gel Filling and CO2 fractional laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Functioning and Well-being, Economic, and Clinical Impact of Hemophilia A and Its Treatment
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: Available Recombinant, and Human Factor VIII products incl. Kogenate FS (Recombinant Factor VIII, BAY14-2222)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Study of TLN-4601 in Patients With Recurring Glioblastoma Multiforme
Status: TERMINATED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: TLN-4601
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib for Patients With Metastatic or Recurrent Esophageal and Gastroesophageal Junction Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Gastroesophageal Junction Cancer
Interventions: DRUG: Sorafenib, administered orally|PROCEDURE: CT/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Double-target CART-19 and 20 Cells in Non-Hodgkin's Lymphoma (NHL)
Status: RECRUITING
Conditions: Non-hodgkin Lymphoma,B Cell
Interventions: BIOLOGICAL: CART-19 and 20 cells|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Buprenorphine/Naloxone in Reducing Intravenous Buprenorphine Misuse in France ("RIME")
Status: COMPLETED
Conditions: Opioid Dependency
Interventions: DRUG: Buprenorphine (Subutex)|DRUG: Buprenorphine/naloxone (Suboxone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention Study of EMG Biofeedback Assisted Force Control to Treat Stroke Movement Disorder
Status: UNKNOWN
Conditions: Stroke|Feedback, Psychological|Motor Deficit
Interventions: OTHER: EMG biofeedback training|OTHER: U/E exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Efficacy of Viltolarsen in Ambulant Boys With DMD (RACER53-X)
Status: ACTIVE_NOT_RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Viltolarsen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Administration Study of Aripiprazole as an Adjunctive Therapy in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: OPC-14597 (Aripiprazole)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addiction and Behavior Related to Menthol Cigarette Substitutes
Status: COMPLETED
Conditions: Smoking (Tobacco) Addiction
Interventions: BEHAVIORAL: Menthol cigarettes substitutes|BEHAVIORAL: Usual brand menthol cigarettes and substitutes|BEHAVIORAL: Menthol cigarettes substitutes and menthol cigarettes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Postplacental Insertion of Levonorgestrel-releasing Intrauterine System (LNG-IUS) After Cesarean vs. Interval Insertion
Status: TERMINATED
Conditions: Healthy
Interventions: DEVICE: Levonorgestrel-releasing intrauterine system (LNG-IUS)|DEVICE: Levonorgestrel-releasing intrauterine system (LNG-IUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Community-engaged Hypertension Prevention Program in Black Men
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension
Interventions: BEHAVIORAL: Community-to-Clinic Linkage Implementation Program in Barbershops (CLIP)|BEHAVIORAL: Barbershop-Based Facilitation (BF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intervening to Reduce Suicide Risk in Veterans With Substance Use Disorders
Status: COMPLETED
Conditions: Suicide|Suicidal Ideation|Substance-Related Disorders
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy (CBT)|BEHAVIORAL: Supportive Psycho-education (SPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of DBL-4pen Mobile Application in Patients With Type 2 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: Use of the device DBL-4pen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recurrent Stenoses in Arteriovenous Fistula (AVF) for Dialysis Access: CuttIng ballooN angioplaSTy Combined wITh Paclitaxel drUg coaTed Balloon Angioplasty, an observatIONal Clinical Study
Status: COMPLETED
Conditions: Dialysis Access Malfunction
Interventions: DEVICE: Cutting balloon followed by paclitaxel coated balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain Control With Lipossomic Extended Release Bupivacaine
Status: UNKNOWN
Conditions: Pain, Postoperative|Lung Cancer
Interventions: DRUG: Bupivacaine liposome|DRUG: Bupivacaine / Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tacrolimus for the Treatment of Superficial Kaposiform Hemangioendothelioma and Tufted Angioma
Status: RECRUITING
Conditions: Tacrolimus, Kaposiform Hemangioendothelioma, Tufted Angioma
Interventions: DRUG: Tacrolimus ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modulation of Repetitive Transcranial Magnetic Stimulation on Hippocampal Neurogenesis and Functional Network in Patients With Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DEVICE: repetitive transcranial magnetic stimulation(DLPFC)|DEVICE: repetitive transcranial magnetic stimulation(LPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of FYU-981 in Hyperuricemia With or Without Gout
Status: COMPLETED
Conditions: Hyperuricemia
Interventions: DRUG: FYU-981 High dose, (Oral daily dosing for 8 weeks)|DRUG: FYU-981 Middle dose, (Oral daily dosing for 8 weeks)|DRUG: FYU-981 Low dose, (Oral daily dosing for 8 weeks)|DRUG: Placebo, (Oral daily dosing for 8 weeks)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vernakalant Versus Ibutilide In Recent-Onset Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Brinavess (Vernakalant)|DRUG: Corvert (Ibutilide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nordic Everolimus (Certican) Trial in Heart and Lung Transplantation
Status: COMPLETED
Conditions: Disorder Related to Cardiac Transplantation
Interventions: DRUG: Everolimus|DRUG: Mycophenolic acid (MPA)/azathioprine (AZA)|DRUG: Calcineurin inhibitors (CNI)|DRUG: Steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparative Health Status and Quality of Life of Patients With Sickle Cell Disease (SCD) Who Underwent Matched-sibling Hematopoietic Stem Cell Transplantation Versus Non Transplanted SCD Case-control Patients
Status: NOT_YET_RECRUITING
Conditions: Sickle Cell Disease
Interventions: OTHER: Spermogram|OTHER: Hospital Anxiety and Depression Scale (HADS)|OTHER: SF36 Quality of life questionnaire|OTHER: Psychologist interview|OTHER: Optional sera banking|OTHER: Optional DNA banking
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER