pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: EXCEL: Exercise for Cancer to Enhance Living Well
Status: RECRUITING
Conditions: Cancer|Head and Neck Cancer|Colon Cancer|Breast Cancer|Prostate Cancer|Cancer Caregivers
Interventions: BEHAVIORAL: Group Exercise Classes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacists Coordinated Care Oncology Model (PCOM) for Patients Taking Oral Anti-cancer Medications
Status: TERMINATED
Conditions: Chronic Myeloid Leukemia|Chronic Lymphocytic Leukemia|Multiple Chronic Conditions
Interventions: OTHER: Patient Reported Outcome Measure (PROM)|OTHER: Comprehensive Medication Review (CMR)|OTHER: Communications between oncology and primary care pharmacists
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Different Relaxation Interventions on Reducing Stress in Chinese Breastfeeding Mothers
Status: COMPLETED
Conditions: Stress-related Problem|Breastfeeding|Relaxation Therapy|Psychological Stress
Interventions: COMBINATION_PRODUCT: five relaxation treatments and one control
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Toric IOL Implantation and Opposite Clear Corneal Incision During Cataract Surgery to Correct Corneal Astigmatism
Status: COMPLETED
Conditions: Cataract|Corneal Astigmatism
Interventions: DEVICE: toric IOL|PROCEDURE: IOL combined with opposite clear corneal incision (OCCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IV Study to Evaluate the Efficacy of AMNIOEXCEL in Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcers
Interventions: OTHER: AMNIOEXCEL|OTHER: Standard of Care, Diabetic Foot Ulcers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance Of aNtiplatElet Therapy in Patients With Coronary Stenting Undergoing Surgery (MONET BRIDGE)
Status: UNKNOWN
Conditions: Platelet Aggregation Inhibitors
Interventions: DRUG: Cangrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, PK and PD Study of Neu-120 in the Treatment of Levodopa-induced Dyskinesia
Status: TERMINATED
Conditions: Levodopa-induced Dyskinesia
Interventions: DRUG: Neu-120
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dynamics of the Upper and Lower Airway Respiratory Microbiomes Associated With Severe Infant Asthma
Status: RECRUITING
Conditions: Asthma in Children|Asthma
Interventions: OTHER: Blood sample|OTHER: Expectoration|OTHER: Nasopharyngeal swab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Development of a New Rapid Diagnostic Test to Support Onchocerciasis Elimination
Status: NOT_YET_RECRUITING
Conditions: Onchocerciasis|Loiasis|Mansonelliasis|Healthy Volunteers
Interventions: BIOLOGICAL: Biological samples collection (blood drawing + feces)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Mild Supplementation of Arabinoxylan Fiber Improves Homa Index in Overweight and Obese Subjects.
Status: UNKNOWN
Conditions: Nutritional and Metabolic Diseases
Interventions: DIETARY_SUPPLEMENT: Arabinoxylan Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Risk Reducing Salpingectomy With Delayed Oophorectomy as an Alternative to Risk- Reducing Salpingo-oophorectomy in High Risk-Women to Assess the Safety of Prevention - US Cohort Study
Status: RECRUITING
Conditions: Ovarian Cancer|Fallopian Tube Cancer
Interventions: OTHER: RIsk-Reducing Salpingectomy (RRS)|OTHER: Risk-Reducing Oophorectomy-RRO|OTHER: Risk-Reducing Salpingo-Oophorectomy-RRSO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Extension Study for the Port Delivery System With Ranibizumab (Portal)
Status: RECRUITING
Conditions: Neovascular Age-Related Macular Degeneration
Interventions: DRUG: PDS Implant with Ranibizumab 100 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Restylane Perlane to Shape the Nasal Dorsum and/or Nasal Root
Status: COMPLETED
Conditions: Nasal Augmentation
Interventions: DEVICE: Restylane Perlane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fat-induced Release of GLP-1 in Humans
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Tributyrin|DIETARY_SUPPLEMENT: C8-diet oil|DIETARY_SUPPLEMENT: Olive oil|DIETARY_SUPPLEMENT: Carrot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Using Open Contest and Neuro-influence Experiment to Develop and Evaluate PrEP Promotion Messages for High Risk Men
Status: RECRUITING
Conditions: HIV/AIDS
Interventions: BEHAVIORAL: PrEP campaign messages developed via open contest|BEHAVIORAL: PrEP campaign messages developed via social marketing approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Potential Increased Risk of Seizures Among Metastatic Castration-Resistant Prostate Cancer (mCRPC) Patients Treated With Enzalutamide
Status: COMPLETED
Conditions: Metastatic Castration-resistant Prostate Cancer (mCRPC)
Interventions: DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of AGN201781 in Neuropathic Pain
Status: TERMINATED
Conditions: Neuralgia
Interventions: DRUG: AGN201781|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Sublingual Dexmedetomidine For Moderate To Severe Agitation In Inpatients With Schizophrenia Or Bipolar Disorder
Status: RECRUITING
Conditions: Schizophrenia Agitation|Schizo Affective Disorder|Bipolar Disorder|Dexmedetomidine
Interventions: DRUG: Dexmedetomidine|DRUG: Lorazepam 2 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Milk Thistle in Body Dysmorphic Disorder
Status: WITHDRAWN
Conditions: Body Dysmorphic Disorder
Interventions: DRUG: Milk Thistle|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Of Allogeneic Mesenchymal Stromal Cells in Pediatric Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases
Interventions: BIOLOGICAL: Allogeneic bone marrow-derived mesenchymal stromal cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation
Status: TERMINATED
Conditions: Thalassemia|Sickle Cell Disease|Glanzmann Thrombasthenia|Wiskott-Aldrich Syndrome|Chronic-granulomatous Disease|Severe Congenital Neutropenia|Leukocyte Adhesion Deficiency|Schwachman-Diamond Syndrome|Diamond-Blackfan Anemia|Fanconi Anemia|Dyskeratosis-congenita|Chediak-Higashi Syndrome|Severe Aplastic Anemia
Interventions: DRUG: Alefacept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiparametric Assessment of Maternal Vascular Function in the Prediction of Hypertensive Disorders of Pregnancy
Status: NOT_YET_RECRUITING
Conditions: Preeclampsia|Hypertensive Disorder of Pregnancy
Interventions: DEVICE: Arterial applanation tonometry|DEVICE: In vivo endothelial glycocalyx measurement|DIAGNOSTIC_TEST: Serum markers of angiogenesis and endothelial dysfunction|DIAGNOSTIC_TEST: Blood chemistry test|DIAGNOSTIC_TEST: Serum xanthine oxidase activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Herbal Medicine in Relieving Symptoms and Change of Quality of Life of Patients With Irritable Bowel Syndrome (IBS)
Status: COMPLETED
Conditions: Colonic Diseases, Functional
Interventions: DRUG: Traditional Chinese Medicine|DRUG: Holopon|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Laparoendoscopic Single-site Surgery and Multi-port Laparoscopy in Treating Uterine Fibroids
Status: ACTIVE_NOT_RECRUITING
Conditions: Uterine Fibroid|Uterine Sarcoma|Uterine Leiomyosarcoma
Interventions: PROCEDURE: TU-LESS|PROCEDURE: MPLS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intradialytic Physical ACTIvity in Addition to a NUTritional Support on Protein Energy Wasting and Physical Functioning in Chronic Hemodialysis Patients ("ACTINUT" Study)
Status: TERMINATED
Conditions: Chronic Renal Failure, Hemodialysis Treatment, Protein-energy Wasting
Interventions: DEVICE: Exercise training in addition to nutritional support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transabdominal and Transvaginal Sonography in Medical Abortion
Status: COMPLETED
Conditions: Abortion Early
Interventions: PROCEDURE: Transabdominal sonography|PROCEDURE: Transvaginal sonography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prophylactic Pyloric Balloon Dilatation During Ivor Lewis Oesophagectomy
Status: COMPLETED
Conditions: Postprocedural Delayed Gastric Emptying
Interventions: DEVICE: 20 mm CRE balloon|DIAGNOSTIC_TEST: OGD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Nivolumab and All-trans Retinoic Acid for Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Effect of Drug
Interventions: DRUG: Nivolumab|DRUG: all trans retinoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thermal Biofeedback for the Treatment of Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathy, Painful
Interventions: BEHAVIORAL: Thermal Biofeedback Assisted Relaxation|BEHAVIORAL: Discussion with therapist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Family-based Prevention of Diabetes Through Eating Habits and Physical Activity
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Family Health|Health Behavior|Healthy Lifestyle|Prediabetic State|Telemedicine
Interventions: BEHAVIORAL: Healthy meals and physical activity in families with type 2 diabetes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sensor-based Assessment and Rehabilitation of Balance in Neurological Diseases
Status: UNKNOWN
Conditions: Stroke|Multiple Sclerosis|Parkinson Disease
Interventions: DEVICE: Experimental Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brivaracetam as add-on Treatment of Unverricht-Lundborg Disease (ULD) in Adolescents and Adults
Status: COMPLETED
Conditions: Unverricht-Lundborg Disease
Interventions: OTHER: Placebo|DRUG: BRV 2.5 mg|DRUG: BRV 25 mg|DRUG: BRV 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bcl-2 Inhibitor GDC-0199 in Combination With Obinutuzumab and Ibrutinib in Treating Patients With Relapsed, Refractory, or Previously Untreated Chronic Lymphocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Refractory Chronic Lymphocytic Leukemia
Interventions: DRUG: Bcl-2 Inhibitor GDC-0199|BIOLOGICAL: Obinutuzumab|DRUG: Ibrutinib|OTHER: Pharmacological Study|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Pharmacokinetics of JHL1149 and Bevacizumab (Avastin) in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy Male Subjects
Interventions: BIOLOGICAL: JHL1149|BIOLOGICAL: Bevacizumab|BIOLOGICAL: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Daratumumab in HLA Desensitization Prior to Transplantation
Status: ENROLLING_BY_INVITATION
Conditions: Cardiac Transplant
Interventions: BIOLOGICAL: Daratumumab and hyaluronidase-fihj
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Spatial Navigation for the Early Detection of Alzheimer's Disease.
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Alzheimer Disease|Healthy Aging
Interventions: DIAGNOSTIC_TEST: Procedure for patients|DIAGNOSTIC_TEST: Procedure for healthy controls
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Femtosecond Laser Assisted Keratotomies for the Management of Corneal Astigmatism
Status: COMPLETED
Conditions: Astigmatism|Cataract
Interventions: DEVICE: Femto-AK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of HMPL-689 for Relapsed/Refractory Marginal Zone Lymphoma and Follicular Lymphoma
Status: RECRUITING
Conditions: Marginal Zone Lymphoma|Follicular Lymphoma
Interventions: DRUG: HMPL-689
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vasopressin vs Norepinephrine on Pulmonary Oxygenation and Lung Mechanics in Patients With Hypertension Therapy During One-lung Ventilation : Preliminary Study
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: 16 mcg / cc of norepinephrine(group N)|DRUG: 0.4 unit / cc of vasopressin(group V)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imaging and Genetic Biomarkers of Parkinson Disease (PD) Onset and Progression in High-risk Families
Status: COMPLETED
Conditions: Parkinson Disease|Parkinsonian Syndrome
Interventions: DRUG: [123I]B-CIT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Safety, Tolerability and Pharmacokinetics Study of RAY1216 in Healthy Adult Participants
Status: COMPLETED
Conditions: COVID-19 (Coronavirus Disease 2019)
Interventions: DRUG: RAY1216 dose 1|DRUG: RAY1216 dose 2|DRUG: RAY1216 dose 3|DRUG: RAY1216 dose 4 &ritonavir|DRUG: RAY1216 dose 5|DRUG: RAY1216 dose 6|DRUG: RAY1216 dose 7|DRUG: RAY1216 dose 8|DRUG: RAY1216 dose 9|DRUG: RAY1216 dose 10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tetravalent Chimeric Dengue Vaccine Trial
Status: COMPLETED
Conditions: Dengue
Interventions: DRUG: Placebo (SC)|DRUG: Placebo (ID)|BIOLOGICAL: Modified Live Tetravalent Chimeric Dengue Vaccine (SC)|BIOLOGICAL: Modified Live Tetravalent Chimeric Dengue Vaccine (ID)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Ultrasound-guided Maxillary Nerve Block Performed After Bimaxillary Osteotomy in Adult Patients
Status: NOT_YET_RECRUITING
Conditions: Maxillary Diseases|Pain, Postoperative|Adult Patients Undergoing Bimaxillary Osteotomy
Interventions: PROCEDURE: Maxillary nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Muscle Training Immediately After Lung Transplantation
Status: RECRUITING
Conditions: Lung Transplantation|Chronic Lung Disease|Muscle Weakness|Rehabilitation
Interventions: DEVICE: IMT- Intervention group|DEVICE: IMT- Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors/Aggressive Fibromatosis
Status: COMPLETED
Conditions: Desmoid Tumors|Aggressive Fibromatosis
Interventions: DRUG: PF-03084014
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidural Analgesia Versus IV Meperidine for Labor Pain Control
Status: COMPLETED
Conditions: Labor Pain
Interventions: PROCEDURE: ECG recording|PROCEDURE: Epidural catheter insertion|DRUG: Intravenous meperidine injection|DRUG: Epidural Bupivacaine and fentanyl injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Treat Clozapine ( CLZ )-Resistant Schizophrenia Comparing CLZ + Haloperidol vs. CLZ + Electroconvulsive Therapy (ECT)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: clozapine+haloperidol|DRUG: clozapine,electroconvulsive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence - Duodart Against Avodart & Omnic
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: DRUG: dutasteride/tamsulosin|DRUG: dutasteride|DRUG: tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Early Intravenous High-dose Vitamin C in Post-cardiac Arrest Shock.
Status: RECRUITING
Conditions: Cardiac Arrest
Interventions: DRUG: Vitamin C (Laroscorbine) + Vitamin B1 (Bevitine)|DRUG: standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Analgesic Efficiency of Quadratus Lumborum Block vs Epidural in Radical Cystectomy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Quadratus Lumborum Block Using Bupivacaine 0.2%|DRUG: Epidural Analgesia Using Bupivacaine 0.25%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Safety and Efficacy Study of Carbidopa-levodopa in Patients With Macular Degeneration
Status: WITHDRAWN
Conditions: Age-related Macular Degeneration
Interventions: DRUG: carbidopa-levodopa 25-100 mg|DRUG: placebo for carbidopa-levodopa 25-100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dietary Interventions on Intestinal Flora and Metabolism
Status: UNKNOWN
Conditions: Dietary Interventions
Interventions: DIETARY_SUPPLEMENT: Dietary fiber intervention|DIETARY_SUPPLEMENT: Normal diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in Children
Status: RECRUITING
Conditions: Malignant Brain Neoplasm|Recurrent Malignant Brain Neoplasm|Refractory Malignant Brain Neoplasm
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: IL13Ralpha2-specific Hinge-optimized 41BB-co-stimulatory CAR Truncated CD19-expressing Autologous T-Lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Validation of a Molecular Test for Ciprofloxacin-Susceptibility in Neisseria Gonorrhoeae
Status: COMPLETED
Conditions: Gonococcal Infection
Interventions: DRUG: Ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Relationship Between Prophylactic Drainage and Postoperative Complications (PPOI) in Crohn's Patients After Surgery
Status: UNKNOWN
Conditions: Crohn's Disease
Interventions: DEVICE: prophylactic drainage|DEVICE: no prophylactic drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ZP4207(Dasiglucagon) Administered to T1D Patients to Assess the PK and PD Compared to Marketed Glucagon
Status: COMPLETED
Conditions: Diabetes Mellitus Type 1
Interventions: DRUG: ZP4207(dasiglucagon) glucagon analogue|DRUG: Glucagon (Native glucagon)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of GlaxoSmithKline (GSK) Biologicals' 10-valent Pneumococcal Conjugate Vaccine.
Status: COMPLETED
Conditions: Hepatitis A
Interventions: BIOLOGICAL: Pneumococcal (vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: In Vivo and in Vitro Efficacy of Antimalarial Treatments in Children in Burkina Faso
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Artesunate-amodiaquine|DRUG: Artemether-lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beta-Blockers for the Prevention of Acute Exacerbations of Chronic Obstructive Pulmonary Disease
Status: TERMINATED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Metoprolol succinate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Administration of Anti-SARS-CoV-2 Convalescent Plasma in Hospitalized, Non-ICU Patients With COVID-19
Status: WITHDRAWN
Conditions: COVID-19
Interventions: DRUG: anti-SARS-CoV-2 plasma|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Differences in Postoperative Symptoms With Four Ureteral Stents
Status: RECRUITING
Conditions: Urinary Stone
Interventions: DEVICE: 6Fr Percuflex ureteral stents|DEVICE: 6Fr Tria ureteral stents|DEVICE: 4.8Fr Tria ureteral stents|DEVICE: 4.8Fr Percuflex ureteral stents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: This Study in Healthy Men and Women Tests How the Body Takes up BI 409306
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 409306 (C-13/N-15)|DRUG: BI 409306
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole-Body Diffusion-Weighted Magnetic Resonance Imaging (MRI) as a Response Biomarker for Metastatic Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer Metastatic
Interventions: DIAGNOSTIC_TEST: Whole-Body Diffusion Weighted MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single Dose Group Stratified Study in Renal Impaired and Healthy Aged and Gender Matched Subjects
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: BAY85-3934|DRUG: BAY85-3934|DRUG: BAY85-3934
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Ruxolitinib (INCB018424) Sustained Release Formulation in Myelofibrosis Patients
Status: COMPLETED
Conditions: Myelofibrosis
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is There an Alternative to Immediate Home Physical Therapy Following Total Knee Arthroplasty
Status: TERMINATED
Conditions: Total Knee Arthroplasty
Interventions: DEVICE: CyMedica e-vive™ System; CY-1000|OTHER: iGetBetter telemedicine physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Telepsychology for Benzodiazepines Withdrawal in Adults Suffering From Hypnotic-dependent Insomnia
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Insomnia|Hypnotic Dependence
Interventions: BEHAVIORAL: Medium duration withdrawal programme with ACT|BEHAVIORAL: Long duration withdrawal programme with ACT|BEHAVIORAL: Medium duration withdrawal programme without ACT|BEHAVIORAL: Long duration withdrawal programme without ACT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research Evaluating an Investigational Medication for Erectile Dysfunction - General ED
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: placebo|DRUG: avanafil|DRUG: avanafil|DRUG: avanafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: rTMS-enhanced Psychotherapy for Borderline Personality Disorder
Status: RECRUITING
Conditions: Borderline Personality Disorder
Interventions: BEHAVIORAL: Dialectical behavioral therapy program|DEVICE: Prefrontal rTMS treatment|DEVICE: Sham rTMS sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Anatomical Right Posterior Sectionectomy of the Liver by IOUS-Guided Finger Compression
Status: UNKNOWN
Conditions: Colorectal Liver Metastases|Hepatocellular Carcinoma|Liver Malignancies
Interventions: PROCEDURE: Anatomical right posterior sectionectomy of the liver by IOUS-guided finger compression.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Diagrammatic Breathing With and Without Resistance in Post Covid Patients on ADLs
Status: COMPLETED
Conditions: COVID-19 Pandemic
Interventions: OTHER: Diaphragmatic breathing with Resistance Training|OTHER: diaphragmatic breathing with out resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy and Safety in Males Subjects With Premature Ejaculation
Status: TERMINATED
Conditions: Premature Ejaculation
Interventions: DRUG: Tramadol Hydrochloride & Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Randomized Trial of Trust in Online Videos About Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: OTHER: Black Doctor Screening Video|OTHER: White Doctor Screening Video|OTHER: Black Patient Screening Video|OTHER: White Patient Screening Video|OTHER: Black Doctor Clinical Trials Video|OTHER: White Doctor Clinical Trials Video|OTHER: Black Patient Clinical Trials Video|OTHER: White Patient Clinical Trials Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Simple Hygiene Versus Alcohol Based Usual Care for Umbilical Cord
Status: UNKNOWN
Conditions: Infection|Skin Diseases, Bacterial|Granuloma
Interventions: BEHAVIORAL: Hygiene|PROCEDURE: Usual alcohol care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Consistency of Three Consecutive Production Lots of Influenza Vaccine in Healthy Subjects 18 to 49 Years Old
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Lot A of Influenza virus vaccine|BIOLOGICAL: Lot B of Influenza virus vaccine|BIOLOGICAL: Lot C of Influenza virus vaccine|BIOLOGICAL: Comparator influenza virus vaccine|BIOLOGICAL: All 3 consecutive lots of influenza virus vaccine pooled
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Gardasil in Females With Juvenile Idiopathic Arthritis (JIA)/Seronegative Arthritis
Status: COMPLETED
Conditions: Arthritis
Interventions: OTHER: Blood Draws for Serum Titers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: LobularCard Trial: Searching for Novel Germline Mutations in Lobular Breast Cancer Patients
Status: RECRUITING
Conditions: Lobular Breast Carcinoma|Lobular in Situ Breast Carcinoma|BRCA1 Mutation|BRCA2 Mutation
Interventions: DIAGNOSTIC_TEST: Illumina panel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Ixekizumab (LY2439821) Versus Adalimumab in Participants With Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: Ixekizumab|DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Blinded, Sham-controlled Trial of Acupuncture for the Management of Joint Pain in Patients With Psoriasis
Status: TERMINATED
Conditions: Psoriasis|Arthralgia
Interventions: OTHER: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Heating Temperature in Major Burns Patients
Status: UNKNOWN
Conditions: Burns|Thermal Injury|Nurse's Role
Interventions: DEVICE: Active external overheating with heating plate, Aragonia ® MTC 400|DEVICE: Active external overheating with air blanket, Equator Level 1® de Smiths Medical
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Open-Label Study to Evaluate Switching From Optimized Stable Antiretroviral Regimens Containing Darunavir to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Fixed Dose Combination (FDC) Plus Darunavir (DRV) in Treatment Experienced HIV-1 Positive Adults
Status: COMPLETED
Conditions: HIV-1|HIV Infections|Acquired Immunodeficiency Syndrome
Interventions: DRUG: E/C/F/TAF|DRUG: DRV|DRUG: Baseline DRV- containing ARV regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Low Dose Total Body Irradiation in Elderly Patients With Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Non Hodgkin's Lymphoma
Interventions: RADIATION: Low dose total body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Imaging Combined With Venous Ultrasonography of the Legs for Pulmonary Embolism
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: PROCEDURE: MRI combined with venous ultrasonography of the legs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety And Tolerability Of Multiple Doses Of PF-04950615 (RN316) In Subjects With Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia|Dyslipidemia
Interventions: BIOLOGICAL: PF-04950615 (RN316)|BIOLOGICAL: PF-04950615 (RN316)|BIOLOGICAL: PF-04950615 (RN316)|BIOLOGICAL: PF-04950615 (RN316)|BIOLOGICAL: PF-04950615 (RN316)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of TENS During the Performance of a Therapeutic Exercise Protocol in Individuals With Knee Osteoarthritis.
Status: RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Therapeutic exercise|DEVICE: Transcutaneous electrical nerve stimulation|DEVICE: Placebo transcutaneous electrical nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Randomized Study of Selective Dorsal Rhizotomy and Physiotherapy Vs Physiotherapy Alone for Spastic Diplegia
Status: UNKNOWN
Conditions: Spastic Diplegia
Interventions: PROCEDURE: Surgery|PROCEDURE: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Inpatient Sleep Loss: Educating and Empowering Patients
Status: COMPLETED
Conditions: Sleep
Interventions: BEHAVIORAL: Patient Empowerment|OTHER: Sleep Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Transverse Thoracic Mobilization With and Without Lower Trapezius Strengthening Exercises
Status: COMPLETED
Conditions: Mechanical Neck Pain
Interventions: OTHER: Lower Trapezius Strengthening Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Relative Bioavailability Study of Enzalutamide in Prostate Cancer Patients
Status: COMPLETED
Conditions: Prostate Cancer|Pharmacokinetics of Enzalutamide
Interventions: DRUG: Enzalutamide tablet|DRUG: Enzalutamide capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Open-Label Safety Study of ADS-5102 in PD Patients With LID
Status: COMPLETED
Conditions: Dyskinesia|Levodopa Induced Dyskinesia (LID)|Parkinson's Disease (PD)
Interventions: DRUG: ADS-5102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Testosterone Therapy in Improving Sarcopenia in Men With Cirrhosis.
Status: UNKNOWN
Conditions: Liver Cirrhosis
Interventions: DRUG: Testosterone Supplementation|DRUG: Standard Medical Treatment|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Acetaminophen for Itch Relief: a Proof of Concept Study in Healthy Subjects
Status: COMPLETED
Conditions: Pruritus
Interventions: DRUG: Acetaminophen|DRUG: Carbomer 980
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Electrical Muscle Activity and Resistance to Movement in Spastic Hemiparetic Patients.
Status: UNKNOWN
Conditions: Cerebrovascular Accident
Interventions: OTHER: Group 2 (G2) NMES is applied in the spastic muscle (gastrocnemius).
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ferrous iROn and cUrcumin sTatus on Inflammatory and Neurotrophic markErs
Status: COMPLETED
Conditions: Iron Deficiency (Without Anemia)
Interventions: DIETARY_SUPPLEMENT: Ferrous Sulphate 65 mg|DIETARY_SUPPLEMENT: Curcumin|OTHER: Placebo (Ferrous Sulphate)|OTHER: Placebo (Curcumin)|DIETARY_SUPPLEMENT: Ferrous Sulphate 18mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trabeculopuncture as Predictive Test for the Success of Ab Interno Trabeculectomy
Status: RECRUITING
Conditions: Open Angle Glaucoma|Pseudoexfoliation Glaucoma
Interventions: DIAGNOSTIC_TEST: Trabeculopuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Study of Fluticasone Furoate(FF)/Umeclidinium Bromide (UMEC)/ Vilanterol (VI) Closed Therapy Versus FF/VI Plus UMEC Open Therapy in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: FF/UMEC/VI|DRUG: FF/VI|DRUG: UMEC|DRUG: Placebo|DRUG: Albuterol/salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Utility of MMPI-2-RF-EX in Detecting Simulated Underreporting of Current Suicide Risk in Military Veterans
Status: COMPLETED
Conditions: Suicidal Ideation|Suicidal
Interventions: DIAGNOSTIC_TEST: Minnesota Multiphasic Personality Inventory -2- Restructured Form - Experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Saturated Fatty Acids and HDL Metabolism
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DIETARY_SUPPLEMENT: Palmitic acid|DIETARY_SUPPLEMENT: Stearic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Suitability of Unobtrusive Bed Monitoring and Wrist-worn Heart Rate Monitor for Patient Monitoring
Status: COMPLETED
Conditions: Arrhythmia|Hemorrhage|Septic Shock|Consciousness, Loss of|Sleep
Interventions: DIAGNOSTIC_TEST: Bed-, wrist- and ECG-sensor monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phototherapy in DM Amputation Ulcers.
Status: WITHDRAWN
Conditions: Diabetes Mellitus|Amputation Stumps|Diabetic Foot
Interventions: RADIATION: LED|PROCEDURE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fosfomycin Versus Meropenem or Ceftriaxone in Bacteriemic Infections Caused by Multidrug Resistance in E.Coli
Status: COMPLETED
Conditions: Infection Due to ESBL Escherichia Coli
Interventions: DRUG: Fosfomycin sodium intravenous|DRUG: Meropenem intravenous|DRUG: Ceftriaxone intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Mobile Application to Improve Postoperative Outcomes in Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer|Surgery
Interventions: DEVICE: Care 4 Today ® (Johnson and Johnson) mobile app
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose Ranging Study to Assess the Safety and Efficacy of SCV-07 for the Delay to Onset of Severe Oral Mucositis in Patients Receiving Chemoradiation Therapy for Head and Neck Cancer
Status: COMPLETED
Conditions: Oral Mucositis|Head and Neck Cancer
Interventions: DRUG: Placebo|DRUG: SCV-07|DRUG: SCV-07
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Left Atrial Appendage Occlusion Study III
Status: COMPLETED
Conditions: Cardiac Surgery With Cardiopulmonary Bypass|Atrial Fibrillation
Interventions: OTHER: Left Atrial Appendage Occlusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Safety and Immunogenicity Evaluation of Live Attenuated Influenza Vaccine
Status: UNKNOWN
Conditions: Influenza Prevention
Interventions: BIOLOGICAL: Live Attenuated Influenza Vaccine(non freeze-dried)|BIOLOGICAL: Live Attenuated Influenza Vaccine(freeze-dried)|BIOLOGICAL: Live Attenuated Influenza Vaccine placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Kidney Fat in Type 2 Diabetes and the Effects of Ezetimibe
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Diabetic Kidney Disease
Interventions: DRUG: Ezetimibe 10mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ib Trial of MSP3 LSP in Children in Tanzania
Status: UNKNOWN
Conditions: Malaria
Interventions: BIOLOGICAL: MSP 3 Long Synthetic Peptide|BIOLOGICAL: MSP3 vaccine|BIOLOGICAL: Hepatitis B vaccine|BIOLOGICAL: MSP3 candidate vaccine|BIOLOGICAL: Hepatitis B control vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Respiratory Muscle Training Program in Patients With Multiple Sclerosis
Status: ENROLLING_BY_INVITATION
Conditions: Multiple Sclerosis|Respiration Disorders
Interventions: OTHER: Conventional treatment|OTHER: Experimental treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/IIa Study for the Treatment of Uveitis With Iontophoresis
Status: WITHDRAWN
Conditions: Uveitis
Interventions: DEVICE: Iontophoresis second generation Eyegate II device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical System Accuracy Evaluation With OneTouch® Verio Flex Blood Glucose Monitoring System (BGMS)
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DEVICE: Blood glucose monitoring systems for self-testing (BGMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Optimal Treatment of Acute Skeletal Muscle Injury
Status: NOT_YET_RECRUITING
Conditions: Muscle Strain, Multiple Sites|Inflammation
Interventions: DRUG: Naproxen 500 Mg|PROCEDURE: Rehabilitation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Postnatal Depression, Attachment and Self-defining Memories
Status: UNKNOWN
Conditions: Postnatal Depression
Interventions: BEHAVIORAL: Evaluation of the quality attachment : "Adult Attachment Narratives" and "CaMir scale"|BEHAVIORAL: Evaluation of the self-defining memories : "Specific Questionnaire during an interview"
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A 3-week Study Investigating Patient Use and Functionality of Formoterol in a Novel Inhalation Device in Patients With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Utility of the Alaris MidLatencyAuditoryEvoked Potentials Monitor to Titrate the Anesthetic-Hypnotic Component of Anesthesia
Status: SUSPENDED
Conditions: Scheduled General Anesthesia
Interventions: DEVICE: Alaris AEP monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Epi-on Corneal Cross-linking in Eyes With Progressive Keratoconus
Status: COMPLETED
Conditions: Progressive Keratoconus
Interventions: DRUG: Test Article A|DRUG: Test Article B|DRUG: Placebo|DEVICE: KXL medical device system|DEVICE: KXL medical device system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Efficacy and Safety of HalfLytely Vs Visicol Prior To Colonoscopy.
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: HalfLytely|DRUG: Visicol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE|Primary Purpose:
Clinical trial: A Study of ABBV-428, an Immunotherapy, in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors Cancer
Interventions: DRUG: ABBV-428|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT