pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: [18F]F-DOPA Imaging in Patients With Autonomic Failure
Status: RECRUITING
Conditions: Autonomic Failure|Pure Autonomic Failure|Parkinson Disease|Multiple System Atrophy|Dementia With Lewy Bodies
Interventions: DRUG: [18F]FDOPA|DRUG: Carbidopa 200mg oral dose|DRUG: Entacapone 400mg oral dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vorapaxar Study for Maturation of AV Fistulae for Hemodialysis Access
Status: COMPLETED
Conditions: AV Fistula
Interventions: DRUG: Vorapaxar sulfate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Status of Parathyroid Hormone Secretion in Covid-19 Patients
Status: COMPLETED
Conditions: COVID-19 Infection|Parathyroid Gland|Parathyroid Hormone|Calcium|Phosphorus|Alkaline Phosphatase
Interventions: DIAGNOSTIC_TEST: Venous blood was collected for biochemistry testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Minimally Invasive Surgery vs. Endoscopy Randomized (MISER) Trial for Necrotizing Pancreatitis
Status: COMPLETED
Conditions: Necrosis of Pancreas|Infected Pancreatic Necrosis
Interventions: PROCEDURE: Endoscopic treatment|PROCEDURE: Minimally invasive surgical necrosectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyaluronic Acid Gel in Ridge Preservation
Status: COMPLETED
Conditions: Hyaluronic Acid Gel for Preservation the Extraction Socket
Interventions: DRUG: Hyaluronic acid|OTHER: empty socket
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Economic Impact of mNGS on Diagnosis of Post-neurosurgical Central Nervous System Infection
Status: RECRUITING
Conditions: Central Nervous System Infections
Interventions: DIAGNOSTIC_TEST: mNGS|DIAGNOSTIC_TEST: The traditional microbiological cultures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Comparing Adapalene and Benzoyl Peroxide Gel 0.1%/2.5% to Epiduo® and Both to a Placebo Control in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Adapalene and Benzoyl Peroxide Gel 0.1%/2.5%|DRUG: Epiduo® Gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tai Chi for the Prophylaxis of Episodic Migraine: the Efficacy Examination and Mechanism Exploration
Status: NOT_YET_RECRUITING
Conditions: Migraine Disorders
Interventions: BEHAVIORAL: Tai Chi training|DRUG: Standard prophylactic medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dietary Antioxidants to Prevent Cardiovascular Disease
Status: COMPLETED
Conditions: Hypercholesterolemia|Healthy
Interventions: DIETARY_SUPPLEMENT: red wine|DIETARY_SUPPLEMENT: resveratrol|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of a New Resurfacing Hip Prosthesis
Status: COMPLETED
Conditions: Osteoarthritis, Hip
Interventions: DEVICE: Articular Surface Replacement (ASR) hip prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Safety, Tolerability and Blood Concentrations of Single Doses of AZD3839 in Healthy Volunteers
Status: COMPLETED
Conditions: Alzheimer's Disease|Safety|Tolerability|Blood Concentration|Healthy Volunteers
Interventions: DRUG: AZD3839|DRUG: AZD3839 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dosing and Safety Study of E7820 in Patients With a Malignant Solid Tumor or Lymphoma
Status: COMPLETED
Conditions: Neoplasms|Lymphoma, Malignant
Interventions: DRUG: E7820
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simulator Versus Box Trainer on Laparoscopic Suturing
Status: COMPLETED
Conditions: Simulation Training, Laparoscopy
Interventions: OTHER: Virtual reality simulator|OTHER: Box trainer|DEVICE: Simbionix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: APRiCOT-B: Study to Evaluate Apricoxib in Combination With Lapatinib and Capecitabine in the Treatment of HER2/Neu+ Breast Cancer (TP2001-202)
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: apricoxib + lapatinib + capecitabine|DRUG: placebo + lapatinib + capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pancreaze (Pancrelipase) for Patients With Pancreatic Adenocarcinoma With Cachexia and Exocrine Pancreatic Insufficiency
Status: RECRUITING
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Pancrelipase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open Label, Single Arm Trial to Characterize Patients With Metastatic RCC Treated With Everolimus After Failure of the First VEGF-targeted Therapy (MARC-2)
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma|Failure of Exactly One Prior VEGF-targeted Therapy
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transarterial Chemoperfusion: Cisplatin, Methotrexate, Gemcitabine for Unresectable Pleural Mesothelioma
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Pleural Mesothelioma|Mesothelioma
Interventions: DRUG: Cisplatin|DRUG: Methotrexate|DRUG: Gemcitabine|OTHER: Lung Cancer Symptom Scale for Mesothelioma Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "How Awareness and Subjectivity Modulate the Placebo Effect"
Status: RECRUITING
Conditions: 3 Placebo Groups in a Cycle Ergometer Session With Healthy Participants
Interventions: OTHER: Neutral ginger-flavored drink described as energizing, hypoglycemic, caffeine-based drink|OTHER: Neutral ginger-flavored drink|OTHER: Neutral ginger-flavored drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety of Inhaled Insulin With Type 1 and Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes, Type 1|Diabetes, Type 2
Interventions: DRUG: Technosphere® Insulin Inhalation Powder|DRUG: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of A-319 in the Treatment of Active/Refractory Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: A-319
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Patients With Trophic Ulcers Using Mesenchymal Stem Cells
Status: COMPLETED
Conditions: Trophic Ulcer
Interventions: BIOLOGICAL: Autologous adipose-derived mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study on the Use of Ivermectin as an Outpatient Treatment Option for COVID-19
Status: UNKNOWN
Conditions: Covid19|COVID-19 Pneumonia|COVID-19 Respiratory Infection|COVID-19 Acute Bronchitis
Interventions: DRUG: Ivermectin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Safety and Effectiveness of Cidofovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Cidofovir|DRUG: Probenecid
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: High Definition CT Coronary Angiography Accuracy Trial
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: RADIATION: HD-CTCA with Adaptive statistical iterative reconstruction (ASIR)|RADIATION: Active Comparator: Invasive coronary angiography (ICA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Apneic Oxygenation With a Nasal Cannula in the Obese and Morbidly Obese Surgical Patient
Status: COMPLETED
Conditions: Apneic; Oxygenation
Interventions: OTHER: Oxygen|OTHER: Air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurogenic Inflammation in Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Polyneuropathies|Arthropathy, Neurogenic
Interventions: OTHER: Intracutaneous injection of Candida albicans antigen.|OTHER: Temperature measurement.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Does Dry Needling Affect Treatment Outcomes of Interlaminar Epidural Steroid Injection in Cervical Disc Herniation?
Status: COMPLETED
Conditions: Pain, Myofacial|Pain, Neck|Pain, Chronic
Interventions: PROCEDURE: Cervical interlaminar epidural steroid injection|PROCEDURE: Dry needling|PROCEDURE: Sham dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Substrate Versus Trigger Ablation for Paroxysmal Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: FIRM Ablation|PROCEDURE: Conventional AF ablation with PVI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Oral Feeding vs Traditional Post-operative Care In Emergency Abdominal Surgeries
Status: COMPLETED
Conditions: Perforated Duodenal Ulcer
Interventions: DIETARY_SUPPLEMENT: Early oral feeding/Enhanced recovery after surgery protocols
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Circulating Oxytocin Changes in Response to the Oxytocin System Stimulator MDMA in Patients With Diabetes Insipidus and Healthy Controls
Status: COMPLETED
Conditions: Diabetes Insipidus
Interventions: DIAGNOSTIC_TEST: study intervention: 3,4-methylenedioxymethamphetamine (MDMA, ecstasy)|DIAGNOSTIC_TEST: Control intervention: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Probiotic for the Prevention of Functional Disorders in Childhood
Status: UNKNOWN
Conditions: Gastroenteritis
Interventions: OTHER: Lactobacillus Rhamnosus Strain GG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Test the Safety/Tolerability of Increasing Doses of LNP1892 Versus Placebo in Healthy Male/Female Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LNP1892|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Inferiority of Gatifloxacin/Prednisolone Association vs Isolated Administration in Prevention of Ocular Infection/Inflammation
Status: COMPLETED
Conditions: Ocular Infection and Inflammation
Interventions: DRUG: 0.3% gatifloxacin and 1.0% prednisolone acetate association|DRUG: isolated 0.3% gatifloxacin and 1.0% prednisolone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double-blind Clinical Trials of Probiotic Products in Oral Health.
Status: COMPLETED
Conditions: Probiotics|Oral Health|Probiotic Metabolites
Interventions: DIETARY_SUPPLEMENT: Combined probiotics (1)|DIETARY_SUPPLEMENT: Combined probiotics (2)|DIETARY_SUPPLEMENT: Combined heat-killed probiotics (1)|DIETARY_SUPPLEMENT: Combined heat-killed probiotics (2)|DIETARY_SUPPLEMENT: Probiotic metabolites|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Maternal Counseling for Preterm Deliveries, Assessing an Effective Method of Counseling
Status: COMPLETED
Conditions: Pregnancy Preterm|Counseling
Interventions: OTHER: Verbal counseling|OTHER: Verbal, pictorial, written counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: N-acetylcysteine Given IV With Cisplatin and Paclitaxel in Patients With Ovarian Cancer
Status: WITHDRAWN
Conditions: Ovarian Carcinoma, Stage 3 or 4|Epithelial Ovarian Carcinoma|Primary Peritoneal Carcinoma
Interventions: DRUG: Paclitaxel|DRUG: N-acetylcysteine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder
Status: RECRUITING
Conditions: Opioid Use Disorder
Interventions: DRUG: Psilocybin|DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerability, Pharmacokinetics and Dopamine ß-hydroxylase (DßH) Inhibition Profile of BIA 5-453
Status: COMPLETED
Conditions: Hypertension|Chronic Heart Failure
Interventions: DRUG: BIA 5-453|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of ONO-7475 With and Without ONO-4538 in Subjects Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Advanced or Metastatic Solid Tumors
Interventions: DRUG: ONO-7475|DRUG: ONO-7475 + ONO-4538
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dasatinib Combined With Quercetin to Reverse Chemo Resistance in Triple Negative Breast Cancer
Status: RECRUITING
Conditions: Triple-negative Breast Cancer
Interventions: DRUG: Quercetin|DRUG: Dasatinib|DRUG: Taxane/Anthracycline/Eribulin Mesylate/Vinorelbine/Capecitabine/Carboplatin/UTD1/platinum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Orthopedic Outpatient Consultation by Help of Telemedicine
Status: COMPLETED
Conditions: Orthopedic Disorders
Interventions: OTHER: Telemedicine consultation|OTHER: Standard care in orthopaedic outpatient clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bubble PEP Training Among Patient With Chronic Obstructive Pulmonary Disease in Pulmonary Function Effects
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease With Exacerbation|Chronic Obstructive Pulmonary Disease Exacerbation|Chronic Pulmonary Disease
Interventions: DEVICE: bubble PEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acute Transcranial Bright Light on Anxiety Symptoms
Status: COMPLETED
Conditions: Anxiety
Interventions: DEVICE: Transcranial bright light device|DEVICE: Transcranial sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real Time Myocardial Perfusion Echocardiography for Coronary Allograft Vasculopathy
Status: COMPLETED
Conditions: Cardiac Allograft Vasculopathy
Interventions: DRUG: Perflutren Lipid Microsphere|PROCEDURE: RTMPE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of CER-001 on Atherosclerosis in Acute Coronary Syndrome (ACS) Patients - Efficacy and Safety: The CHI SQUARE Trial
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Placebo|DRUG: CER-001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MOOC Applications Related to Shared Decision Making in Bariatric Surgery
Status: NOT_YET_RECRUITING
Conditions: Bariatric Surgery Candidate|Shared Decision Making|Informed Consent
Interventions: OTHER: course (MOOC) patient education|OTHER: standard patient consent process
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Magnetic Resonance Diagnostics of Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Diabetic Polyneuropathy|Hereditary Axonal Neuropathy|Hereditary Demyelinated Neuropathy|Polyneuropathy, Inflammatory Demyelinating, Chronic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study to Assess Opiate Withdrawal Signs and Symptoms in Opioid Dependent Patients
Status: TERMINATED
Conditions: Chronic Pain
Interventions: DRUG: EMBEDA™ (morphine sulfate/naltrexone hydrochloride) crush|DRUG: EMBEDA™ (morphine sulfate/naltrexone hydrochloride) whole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Clinical Study of PAL-222 Targeting Patients With Myopic Chorioretinal Atrophy (PAMyCA)
Status: RECRUITING
Conditions: Myopic Chorioretinal Atrophy
Interventions: PROCEDURE: Pars plana vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cilostazol vs. Aspirin in Acute Non-cardioembolic Stroke With Cerebral mIcrobleeds
Status: RECRUITING
Conditions: Cerebral Microbleeds|Stroke
Interventions: DRUG: Cilostazol|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of RapidPulseTM Aspiration System as Frontline Approach for Stroke Patients
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DEVICE: RapidPulseTM Aspiration System|DEVICE: Standard of Care Aspiration Thrombectomy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Physiotherapy to Treat the Urinary Incontinence and Erectile Dysfunction Post Retropubic Prostatectomy
Status: COMPLETED
Conditions: Urinary Incontinence|Erectile Dysfunction
Interventions: PROCEDURE: group of pelvic floor exercises|PROCEDURE: anal electrostimulation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Presurgical Planning With Functional MRI (fMRI) Mapping of Motor Cortex in Patients With Cerebral Tumors
Status: COMPLETED
Conditions: Brain Tumors
Interventions: PROCEDURE: Presurgical MRI|PROCEDURE: functional MRI (fMRI) of the brain
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The SAVVY Guidewire in Transcatheter Aortic Valve Replacement Procedures
Status: COMPLETED
Conditions: Aortic Valve Disease|Transcatheter Aortic Valve Replacement|Aortic Valve Stenosis|Hemodynamic Measurement
Interventions: DEVICE: SAVVY guidewire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prevalence of Sialorrhea in Patients Treated With Clozapine
Status: COMPLETED
Conditions: Sialorrhea|Clozapine Adverse Reaction|Quality of Life
Interventions: PROCEDURE: Evaluation of sialorrhea through questionnaires that measure daytime and nighttime sialorrhea and the impact on quality of life.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Role of Surgery in Patients With Coronavirus Disease - 19 (COVID-19) Related Thoracic Complications
Status: COMPLETED
Conditions: Surgical Complication|COVID-19|Pneumothorax|Empyema, Pleural|Abscess|Hemothorax|Thoracic
Interventions: PROCEDURE: Lung parenchyma resection|PROCEDURE: Empyemectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Brazilian Cardioprotective Diet, Phytosterols and Krill Oil in Patients With Familial Hypercholesterolemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Familial Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: phytosterol|DIETARY_SUPPLEMENT: krill oil|OTHER: Placebo phytosterol|OTHER: Placebo krill oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: KingVision Video Laryngoscopy vs Direct Laryngoscopy - Equivalence Trial
Status: COMPLETED
Conditions: Tracheal Intubation
Interventions: DEVICE: Ambu KingVision Video Laryngoscope aBlade|DEVICE: Miller Direct Laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Extracorporeal SPecific IgE Removal From the Plasma of Allergic Asthma Patients (ESPIRA-study)
Status: COMPLETED
Conditions: Allergic Asthma
Interventions: DEVICE: IgE adsorber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of an Effort Rehabilitation Program for Overweight/Obese Children/Teens on Quality of Life and Wellbeing
Status: COMPLETED
Conditions: Pediatric Obesity
Interventions: OTHER: Eurofit Tests of Physical Fitness (Eurofit)|BEHAVIORAL: Child Health Questionnaire (CHQ)|OTHER: Effort rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Tepotinib on the PK of the P-gp Substrate Dabigatran Etexilate
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dabigatran Etexilate|DRUG: Tepotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Genetic Research of Bone Morphogenetic Protein Receptor-II Gene in Taiwanese Patient With Primary Pulmonary Hypertension
Status: UNKNOWN
Conditions: Pulmonary Hypertension
Interventions: PROCEDURE: for BMPR II study|GENETIC: BMPRII
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Targeting Cognition in Bipolar Disorder With Pramipexole
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Pramipexole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Itacitinib in Participants With Bronchiolitis Obliterans Syndrome Following Lung Transplantation
Status: TERMINATED
Conditions: Bronchiolitis Obliterans Syndrome
Interventions: DRUG: Itacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of TIN816 in Patients With Sepsis-associated Acute Kidney Injury
Status: COMPLETED
Conditions: Acute Kidney Injury Due to Sepsis
Interventions: BIOLOGICAL: TIN816 70 mg lyophilisate powder|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CD388 Intramuscular or Subcutaneous Administration in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: COMBINATION_PRODUCT: CD388 Injection|DRUG: Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Pre-dosing With Methylcellulose or Psyllium on Colonic Fermentation of Inulin
Status: NOT_YET_RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: inulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Effect of NN5401 With the Effect of NN1250 and Insulin Aspart in Type 1 Diabetics
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec|DRUG: insulin degludec/insulin aspart|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Taste and Local Tolerance Study of NLA Nasal Spray in Patients With Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Cetirizine dihydrochloride (10 mg/ml) liposomal formulation|DRUG: Cetirizine dihydrochloride (10 mg/ml) buffer solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-term Trial to Compare the Effects of Liraglutide and Sulphonylurea (Glimepiride) Both in Combination With Metformin on Clinical, Endothelial and Image Markers of Cardiovascular Risk in Patients With Type 2 Diabetes
Status: WITHDRAWN
Conditions: Type 2 Diabetes
Interventions: DRUG: Liraglutide + metformin|DRUG: Glimepiride + metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: The Impact Of SGLT2 -I on Metabolic Dysfunction -Associated Steatotic Liver Disease In Patients With Type 2 Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Fatty Liver, Nonalcoholic
Interventions: DRUG: SGLT2 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of BIO-K+ on Symptoms of Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: L. acidophilus CL1285® + L. casei LBC80R® + L. rhamnosus CLR2®|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study to Evaluate Safety and Efficacy of RM-493 in Obese Participants
Status: COMPLETED
Conditions: Overweight
Interventions: DRUG: Setmelanotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Psychometric Evaluation in Patients With Brain Damage During Neuroinflammation (NeuroPsyc)
Status: ENROLLING_BY_INVITATION
Conditions: Multiple Sclerosis|Epilepsy|Parkinson Disease|Dementia|Stroke
Interventions: BEHAVIORAL: Psychometric Evaluations
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intraoperative Tumor Margin Identification With ICG Dye Imaging
Status: RECRUITING
Conditions: Benign Neoplasm|Malignant Neoplasm
Interventions: DRUG: Indocyanine green|DEVICE: SPY-PHI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: RELISTOR's Effects on Opioid-Induced Constipation
Status: WITHDRAWN
Conditions: OIC
Interventions: DRUG: Relistor Injectable Product|DRUG: Docusate Calcium|DRUG: Bisacodyl|DRUG: Milk of magnesia|DRUG: Magnesium citrate|DRUG: Senna|DRUG: Enema
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Determine the Efficacy and Safety of Luspatercept in Adult and Adolescent Participants With Alpha (α)-Thalassemia
Status: RECRUITING
Conditions: Anemia
Interventions: BIOLOGICAL: Luspatercept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of GlaxoSmithKline Biologicals' Boostrix® Vaccine in Comparison With Decavac™ Vaccine.
Status: COMPLETED
Conditions: Tetanus|Acellular Pertussis|Diphtheria|Diphtheria-Tetanus-acellular Pertussis Vaccines
Interventions: BIOLOGICAL: Boostrix®|BIOLOGICAL: Decavac™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Two-hand Mask Ventilation Technique: Standard V-E Versus Reversal V-E Technique
Status: COMPLETED
Conditions: Intubation
Interventions: PROCEDURE: Standard V-E ventilation technique|PROCEDURE: Reversal V-E ventilation technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sequential Chemotherapy and Lenalidomide Followed by Rituximab and Lenalidomide Maintenance for Untreated Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Mantle Cell Lymphoma|Untreated
Interventions: DRUG: Lenalidomide|DRUG: R-CHOP|DRUG: high-dose cytarabine (HIDAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Submucosal Dissection Versus Surgery in the Treatment of Early Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Early Gastric Cancer
Interventions: PROCEDURE: endoscopic submucosal dissection|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Changes After Major Joint Replacement - Full Trial (Cognigram 2)
Status: ACTIVE_NOT_RECRUITING
Conditions: Postoperative Cognitive Dysfunction|Cognitive Impairment|Mild Cognitive Impairment|Delirium|Cognitive Decline|Cognitive Change|Working Memory|Autoimmune Diseases|Inflammation
Interventions: OTHER: Cognitive Testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of 90Y Zevalin in Nonmyeloablative Transplantation for Lymphoid Malignancies
Status: COMPLETED
Conditions: Lymphoma|Leukemia
Interventions: DRUG: Zevalin Radioimmunotherapy|DRUG: Rituximab|DRUG: Fludarabine|DRUG: Cyclophosphamide|PROCEDURE: Allogeneic Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-dose Chemotherapy and Stem Cell Transplantation, in Patients PET-2 Positive, After 2 Courses of ABVD and Comparison of RT Versus no RT in PET-2 Negative Patients
Status: COMPLETED
Conditions: Hodgkin's Lymphoma
Interventions: DRUG: ABVD|DRUG: ABVD and Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lifestyle and/or Metformin Intervention on Pregnancy Outcome, A Pilot Randomized Controlled Trial
Status: COMPLETED
Conditions: Infertility, Female|Obesity|Insulin Resistance
Interventions: BEHAVIORAL: weight loss intervention|DRUG: metformin intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Durvalumab ,Doxorubicin, and Ifosfamide in Pulmonary Sarcomatoid Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Durvalumab + doxorubicin + ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Identification of Cricoid Cartilage in Cricoid Pressure
Status: UNKNOWN
Conditions: Endotracheal Intubation|General Anesthesia
Interventions: DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Simple Needle Guide Device for Ultrasound-guided Internal Jugular Vein Catheterization in Surgical Patients: a Randomized-controlled Trial
Status: UNKNOWN
Conditions: Patients Undergoing Surgery
Interventions: DEVICE: Sono with Device|DEVICE: Sono only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trial to Evaluate the Bone Metabolism and the Blood Sugar of Evogliptin and Dapagliflozin
Status: UNKNOWN
Conditions: Bone Diseases, Metabolic|Diabetes Mellitus, Type 2
Interventions: DRUG: Evogliptin|DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BTL Emsella Chair Versus Sham for the Treatment of Overactive Bladder
Status: RECRUITING
Conditions: Overactive Bladder Syndrome|Overactive Bladder|Urinary Frequency|Urinary Urgency
Interventions: DEVICE: BTL Emsella Chair|DEVICE: Sham BTL Emsella Chair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Results of Lateral Suspension Surgeries Performed With the V-NOTES (Vaginal-Natural Orifice Transluminal Endoscopic Surgery) Technique
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: lateral suspension via V-NOTES surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Efficacy and Safety of Fermented Soybean(Doenjang Powder) on Intestinal Microflora and Immune Enhancement.
Status: COMPLETED
Conditions: Immunity
Interventions: DIETARY_SUPPLEMENT: TMD21-16 group|DIETARY_SUPPLEMENT: TCD21-55 group|DIETARY_SUPPLEMENT: TFD21-1 group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Efficacy and Safety of RO7198457 in Combination With Atezolizumab Versus Atezolizumab Alone Following Adjuvant Platinum-Doublet Chemotherapy in Participants Who Are ctDNA Positive After Surgical Resection of Stage II-III Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Atezolizumab|DRUG: RO7198457
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Lopinavir/Ritonavir With Raltegravir in HIV-infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: lopinavir/ritonavir and raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Smoking Status and Genetic Risk Factors on Restenosis and Efficacy of Clopidogrel After de Novo Percutaneous Coronary Intervention
Status: UNKNOWN
Conditions: Smoking Status|Genetic Risk Factors|Restenosis|Clopidogrel|Coronary Heart Disease|Percutaneous Coronary Intervention
Interventions: OTHER: clinical restenosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gene Expression Profiles to Categorize Wilms Tumors
Status: COMPLETED
Conditions: Recurrent Wilms Tumor and Other Childhood Kidney Tumors|Stage I Wilms Tumor|Stage II Wilms Tumor|Stage III Wilms Tumor|Stage IV Wilms Tumor|Stage V Wilms Tumor
Interventions: OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Safety of Cabazitaxel (Jevtana) in Patients With Metastatic Hormone Refractory Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer Metastatic
Interventions: DRUG: CABAZITAXEL XRP6258|DRUG: Prednisone|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Newborn Infection Control and Care Initiative for Health Facilities to Accelerate Reduction of Newborn Mortality
Status: UNKNOWN
Conditions: Neonatal Infection
Interventions: BEHAVIORAL: Training HC/VHSG, Health Education, and Supportive Supervision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Open-Label Study of Parsaclisib, in Japanese Participants With Relapsed or Refractory Follicular Lymphoma (CITADEL-213)
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: parsaclisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 506U78 in Treating Patients With Relapsed or Refractory T-cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: DRUG: nelarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Stage IV Breast Cancer
Status: COMPLETED
Conditions: HER2-positive Breast Cancer|Male Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: BIOLOGICAL: HER-2/neu peptide vaccine|PROCEDURE: leukapheresis|BIOLOGICAL: ex vivo-expanded HER2-specific T cells|DRUG: cyclophosphamide|BIOLOGICAL: sargramostim|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of SIBP-01 Or CN-Trastuzumab Plus Docetaxel And Carboplatin In HER2 Positive Breast Cancer
Status: COMPLETED
Conditions: HER2-positive Early Breast Cancer
Interventions: DRUG: SIBP-01|DRUG: Herceptin|DRUG: Docetaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Lóa Study: A Brief Digital Intervention for Women With Intrusive Memories in the SAGA Cohort
Status: RECRUITING
Conditions: Intrusive Memories of Traumatic Event(s)
Interventions: BEHAVIORAL: Brief imagery-competing task|BEHAVIORAL: Brief psychoeducation and signposting task|OTHER: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abdominal Drainage in the Postoperative Period of Liver Transplantation (DRALIT)
Status: NOT_YET_RECRUITING
Conditions: Liver Transplant; Complications|Drainage
Interventions: PROCEDURE: Abdominal drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mindfulness Training: the Effects of a Stress Reduction Program on Older Portuguese-speaking People in Luxembourg
Status: COMPLETED
Conditions: Mindfulness|Healthy Aging
Interventions: BEHAVIORAL: MBSR|BEHAVIORAL: HPP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety, Reactogenicity, and Immunogenicity Trial of CV2CoV mRNA Vaccine Against SARS-CoV-2 in Seropositive Adult Participants
Status: COMPLETED
Conditions: COVID-19|SARS-CoV-2
Interventions: BIOLOGICAL: CV2CoV (2 µg)|BIOLOGICAL: CV2CoV (4 µg)|BIOLOGICAL: CV2CoV (8 µg)|BIOLOGICAL: CV2CoV (12 µg)|BIOLOGICAL: CV2CoV (16 µg)|BIOLOGICAL: CV2CoV (20 µg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Adenoma Detection Rate in Artificial Intelligence-assisted Colonoscopy
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer|Colorectal Adenoma|Colorectal Neoplasms
Interventions: DEVICE: AI-assisted colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SOAR-2: Intervening in Obesity Through Reduction of Dietary Branched Chain Amino Acids
Status: WITHDRAWN
Conditions: Obesity|Diabetes
Interventions: DIETARY_SUPPLEMENT: Control diet|DIETARY_SUPPLEMENT: Low branched-chain amino acids(BCAA) diet|DIETARY_SUPPLEMENT: Low protein diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sedating Antidepressant Improves Driving Safety in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Depression|Excessive Daytime Sleepiness
Interventions: BEHAVIORAL: Driving Simulator Testing|DRUG: Mirtazapine Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Busulfan, Fludarabine, and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Stem Cell Transplant for Hematologic Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Precancerous Condition
Interventions: BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: busulfan|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: mycophenolate mofetil|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: Total Body Irradiation (TBI)|DRUG: Granulocyte colony-stimulating factor (G-CSF)|DRUG: Phenytoin|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sildenafil for Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Emphysema
Interventions: DRUG: sildenafil citrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Interaction and Safety Between NVP-1203-R1 and NVP-1203-R2
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: NVP-1203-R1|DRUG: NVP-1203-R2|DRUG: NVP-1203-R1 and NVP-1203-R2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Optimization of 5-Fluorouracil Dose by Pharmacokinetic Monitoring in Asian Patients With Advanced Stage Cancer
Status: UNKNOWN
Conditions: Cancer (Advanced Stage)
Interventions: DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repair vs Non-repair of the Pronator Quadratus Muscle in Distal Radius Fractures. RCT.
Status: COMPLETED
Conditions: Radius Fractures|Colles' Fracture|Rupture of Muscle|Arm Injuries
Interventions: PROCEDURE: Repair|PROCEDURE: Non-repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an App for Mobile Phones (e-12HR) to Increase Adherence to Mediterranean Diet in University Students
Status: RECRUITING
Conditions: Mediterranean Diet|Diet Habits|Healthy Eating Index
Interventions: BEHAVIORAL: e-12HR app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: FOLFOX Plus Lenvatinib Adjuvant Therapy for Hepatocellular Carcinoma Post-Liver Transplantation
Status: NOT_YET_RECRUITING
Conditions: Liver Cancer|Liver Transplant
Interventions: DRUG: FOLFOX4 regimen|DRUG: lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Post Marketing Study of Apligraf in Non-healing Wounds of Subjects With Venous Leg Ulcers
Status: COMPLETED
Conditions: Venous Ulcer
Interventions: DEVICE: Apligraf|OTHER: Standard of Care Dressing Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Of Osteopathic Manipulative Treatment In NICU: A Multicenter Clinical Trial
Status: COMPLETED
Conditions: Prematurity
Interventions: OTHER: osteopathic manipulative treatment|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT