pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: COvid-19 LongitUdinal Multiethnic BioImaging Assessment of CARDiovascular Sequelae Registry
Status: COMPLETED
Conditions: Covid19|Cardiac Disease|Cardiac Arrhythmia|Myocarditis|Left Ventricular Dysfunction
Interventions: OTHER: Transthoracic echocardiogram (TTE)|OTHER: Cardiovascular Magnetic Resonance (CMR) Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Calcium Hydroxide Versus Premixed Bioceramic Putty in Direct Pulp Capping of Primary Molars
Status: UNKNOWN
Conditions: Direct Pulp Capping
Interventions: OTHER: direct pulp capping in primary molars
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy With or Without Olaparib in Treating Patients With Inflammatory Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Inflammatory Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Olaparib|RADIATION: Radiation Therapy|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Absorption of Corticosteroids in Children With Juvenile Dermatomyositis
Status: COMPLETED
Conditions: Vasculitis, Hypersensitivity|Connective Tissue Diseases|Dermatomyositis|Vasculitis
Interventions: DRUG: Methylprednisolone|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NT-501 CNTF Implant for Ischemic Optic Neuropathy: Safety, Neuroprotection and Neuroenhancement
Status: COMPLETED
Conditions: Ischemic Optic Neuropathy/Optic Nerve Stroke
Interventions: DRUG: NT-501 CNTF Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Healthy Volunteer PK/PD, Safety and Tolerability Study of Andexanet After Betrixaban Dosing
Status: TERMINATED
Conditions: Bleeding
Interventions: BIOLOGICAL: Andexanet alfa (bolus)|DRUG: Betrixaban 80 mg PO QD|BIOLOGICAL: Andexanet alfa (infusion IV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Effects of Virtual Reality and Motor Imagery in Patients With Non-specific Neck Pain
Status: RECRUITING
Conditions: Cervical Pain|Kinesiophobia|Pain
Interventions: OTHER: Virtual Reality|OTHER: Motor Imagery|OTHER: Routine Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Dihydroartemisinin-piperaquine Plus Primaquine on Malaria Transmission in Lampung Province, Sumatra
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Dihydroartemisinin-piperaquine with primaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pre Emptive Analgesics for Pain Relief in Impacted Lower Third Molar Surgery
Status: COMPLETED
Conditions: Impacted Third Molar Tooth
Interventions: DRUG: paracetamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SEM Evaluation of the Quantity of microRepair® on Resin Composite Surfaces: an in Vivo Randomized Clinical Trial.
Status: COMPLETED
Conditions: Dental Caries|Dental Fillings
Interventions: OTHER: Biorepair Total Protection|OTHER: Sensodyne Repair & Protect
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of the Body Posture Correcting Therapy on Pelvic Floor Muscles Function
Status: COMPLETED
Conditions: Urinary Incontinence,Stress
Interventions: OTHER: Manual therapy, exercises and education program|OTHER: Education program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effect of BMS-790052 on the Pharmacokinetics of Ortho Tri-Cyclen® in Healthy Female Subjects
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: BMS-790052|DRUG: Ortho Tri-Cyclen®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy and Safety of Gemcabene in Hypercholesterolemic Patients on Stable Statin Therapy
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Gemcabene|DRUG: Gemcabene|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Training in Evidence-based Treatments in Psycho-Oncology
Status: RECRUITING
Conditions: Distress, Emotional|Depression, Anxiety|Fatigue|Pain|Insomnia
Interventions: BEHAVIORAL: Individualized Evidence-Based Therapy in Cancer (Patients)|BEHAVIORAL: Training in Individualized Evidence-Based Therapy in Cancer (Therapists)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CA209-891: Neoadjuvant and Adjuvant Nivolumab as Immune Checkpoint Inhibition in Oral Cavity Cancer
Status: UNKNOWN
Conditions: Squamous Cell Carcinoma of the Oral Cavity
Interventions: BIOLOGICAL: Nivolumab, Surgery, Radiotherapy|BIOLOGICAL: Nivolumab, Surgery, Chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Blood Transfusion in Consolidation Therapy of Elderly Patients With Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Leukemia, Myelomonocytic, Acute
Interventions: DRUG: umbilical cord blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Factor IX Inhibition in Thrombosis Prevention (The FIXIT Trial)
Status: COMPLETED
Conditions: Venous Thromboembolism|Embolism and Thrombosis|Hip Fractures
Interventions: DRUG: TTP889
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The Insulin Independence Trial (IIT) Evaluating the Safety and Efficacy of Oral Cyclosporine and Oral Lansoprazole for Insulin Independence Among Patients With Existing Type 1 Diabetes
Status: WITHDRAWN
Conditions: Type 1 Diabetes
Interventions: DRUG: Oral Cyclosporine and Oral Lansoprazole|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Investigate Whether PF-04457845 Is Effective In Treating Pain, Is Safe And Tolerable In Patients With Osteoarthritis Of The Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: PF-04457845|DRUG: PF-04457845|DRUG: Naproxen|DRUG: Naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Adacel® Vaccine Administered to Persons 10 Years of Age
Status: COMPLETED
Conditions: Tetanus|Diphtheria|Pertussis
Interventions: BIOLOGICAL: Adacel®: Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Adsorbed|BIOLOGICAL: Adacel®: Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Adsorbed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Non-Surgical Periodontal Therapy on Serum Albumin Levels of Patients on Maintenance Hemodialysis Therapy,
Status: UNKNOWN
Conditions: End Stage Renal Failure on Dialysis|Periodontitis
Interventions: PROCEDURE: non-surgical periodontal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Harnessing Human Potential and Improving Health Span in Women and Their Children
Status: RECRUITING
Conditions: Type 2 Diabetes|Healthy Lifestyle Behaviors|Gestational Diabetes
Interventions: BEHAVIORAL: LvL UP App|BEHAVIORAL: HAPPY App|BEHAVIORAL: Oura Ring And Oura App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of Self-collected Vaginal Swabs as an Innovative Approach to Facilitate Testing for Repeat Chlamydia Infection
Status: COMPLETED
Conditions: Chlamydia Infections
Interventions: PROCEDURE: Self-collected vaginal swab for chlamydia testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The RAFT ECT Study
Status: RECRUITING
Conditions: Major Depressive Episode
Interventions: PROCEDURE: Frontoparietal Ultrabrief Right Unilateral (UBRUL-FP) electroconvulsive therapy|PROCEDURE: Temporoparietal Ultrabrief Right Unilateral (UBRUL-TP) electroconvulsive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Digitally-Supported Shared Decision Making Approach for Coronary Artery Disease Patients During Cardiac Rehabilitation
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiac Rehabilitation|Digital Health|Telerehabilitation
Interventions: DEVICE: SharedHeart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab in Combination With Lenalidomide in Refractory and Relapsed Elderly Patients With Non-GCB DLBCL
Status: UNKNOWN
Conditions: Non-GCB/ABC Diffuse Large B-Cell Lymphoma|High-grade B-cell Lymphoma|Follicular Lymphoma Grade IIIb|Transformed Lymphoma|EBV-Positive DLBCL, Nos|ALK-Positive Anaplastic Large Cell Lymphoma
Interventions: DRUG: PD-1 Antibody|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetes Risk Education and Communication Trial
Status: COMPLETED
Conditions: PreDiabetes|Diabetes Mellitus|Diabetes Mellitus, Type 2|Body Weight|Body Weight Changes
Interventions: BEHAVIORAL: DiRECT|BEHAVIORAL: Usual care (UC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Ixazomib Administered in Combination With Lenalidomide and Low-Dose Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Ixazomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Web-Based Course to Maintain Skills in Nurses Trained to Screen for Dysphagia
Status: COMPLETED
Conditions: Deglutition Disorders|Dysphagia|Stroke
Interventions: OTHER: TOR-BSST© Refresher Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Improving Therapeutic Learning in Depression: Proof of Concept
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: 250 mg DCS|DRUG: 100 mg Modafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Normal Tension and Chronic Open Angle Glaucoma and Cerebrospinal Fluid Composition
Status: UNKNOWN
Conditions: Glaucoma Open-Angle
Interventions: PROCEDURE: Optic nerve sheath fenestration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunological and Viral Response to Antiretrovirals in HIV Patients With CD4 Cell Count Below 100
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: AZT+3TC+IDV+RTV|DRUG: AZT+3TC+EFV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2 Safety and Efficacy Study of AAV-RPE65 Vector to Treat Leber Congenital Amaurosis
Status: COMPLETED
Conditions: Leber Congenital Amaurosis
Interventions: BIOLOGICAL: rAAV2-CB-hRPE65
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of External Focus and Internal Focus Instructions Applied Chronic Low Back Pain: RCT
Status: COMPLETED
Conditions: Physical Therapy Techniques
Interventions: OTHER: external focus task focus in addition to physiotherapy and rehabilitation exercises|OTHER: internal focus task focus in addition to physiotherapy and rehabilitation exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Drug Monitoring in Patients With Difficult-to-Treat Gram-Negative Bacterial Infections
Status: RECRUITING
Conditions: Sepsis|Hemodynamic Instability|Bacterial Infections|Therapeutic Drug Monitoring|Antimicrobial Resistance
Interventions: OTHER: Therapeutic Drug Monitoring (TDM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 90% Effective Dose of Norepinephrine Infusions Under Intensive and Standard Treatment in Preeclamptic Patients
Status: NOT_YET_RECRUITING
Conditions: Adverse Effect
Interventions: DRUG: Alpha-Agonist|DRUG: α-adrenergic receptor agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Of the Effects of Highly Active Antiretroviral Therapy on Kaposi's Sarcoma in Zimbabwe
Status: COMPLETED
Conditions: AIDS-related Kaposi's Sarcoma
Interventions: DRUG: abacavir/3TC/zidovudine|DRUG: abacavir /3TC plus ritonavir boosted lopinavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided vs Landmark Technique for Femoral Arterial Cannulation in Pediatric Cardiac Surgery
Status: COMPLETED
Conditions: Time Needed to Achieve a Successful Cannulation of the Femoral Artery in Pediatric Cardiac Surgery
Interventions: DEVICE: Ultrasound|OTHER: Landmark
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Long-term Safety, Tolerability, and Durability of Treatment Effect of ALKS 3831
Status: COMPLETED
Conditions: Schizophrenia|Schizophreniform Disorder|Bipolar I Disorder
Interventions: DRUG: ALKS 3831
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Antiemetic Drugs in Preventing Delayed Nausea After Chemotherapy in Patients With Cancer
Status: COMPLETED
Conditions: Nausea and Vomiting|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: dolasetron mesylate|DRUG: granisetron hydrochloride|DRUG: ondansetron|DRUG: prochlorperazine|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multicenter Phase 3, Open-Label Study of Bosutinib Versus Imatinib in Adult Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia, Myelogenous, Chronic, Breakpoint Cluster Region-Abelson Proto-oncogene (BCR-ABL) Positive
Interventions: DRUG: Bosutinib|DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Irrigation in Shoulder Arthroscopy
Status: COMPLETED
Conditions: Postoperative Pain|Analgesia
Interventions: DRUG: Lidocaine epinephrine|DRUG: Epinephrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Probiotics for Reduction Of Markers In Subjects With Allergy
Status: COMPLETED
Conditions: Hay Fever|Birch Pollen Allergy
Interventions: DIETARY_SUPPLEMENT: Yoghurt with L. plantarum strain|DIETARY_SUPPLEMENT: Yoghurt with L.casei|DIETARY_SUPPLEMENT: Yoghurt with L. plantarum strain|DIETARY_SUPPLEMENT: Yoghurt with L. plantarum strain|DIETARY_SUPPLEMENT: Yoghurt with L. plantarum strain|DIETARY_SUPPLEMENT: Yoghurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of CS-3150 in Japanese Type 2 Diabetic Subjects With Microalbuminuria
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: CS-3150|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metronomic Docetaxel and Bevacizumab in Patients With Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Docetaxel|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin Pre-Treatment Influences the Risk of Percutaneous Coronary Intervention (PCI) Study 2
Status: UNKNOWN
Conditions: Coronary Artery Disease|Coronary Angioplasty
Interventions: DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Closed-loop Automated Insulin Delivery System by Primary Care & Endocrinology, in Person & Via Telehealth
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Type 1 Diabetes|Diabetes, Autoimmune|Diabetes type1|Autoimmune Diabetes|Diabetes Mellitus, Brittle|Diabetes Mellitus, Insulin-Dependent|Diabetes Mellitus, Insulin-Dependent, 1|Diabetes Mellitus, Juvenile-Onset|Diabetes Mellitus, Ketosis-Prone|Diabetes Mellitus, Sudden-Onset|Insulin-Dependent Diabetes Mellitus 1|Juvenile-Onset Diabetes|Type 1 Diabetes Mellitus
Interventions: DEVICE: Bionic Pancreas|OTHER: Telehealth|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Percutaneous Tracheostomy
Status: COMPLETED
Conditions: Tracheostomy Hemorrhage|Tracheostomy Complications|Other Tracheostomy Complications
Interventions: DEVICE: Ultrasonography (EnVisor Philips Medical Systems)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Pioglitazone and Metformin Combination Therapy in Treating Type 2 Diabetes Mellitus.
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Pioglitazone and metformin|DRUG: Pioglitazone|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Adverse Events and Compare How Oral Ubrogepant and Oral Atogepant Moves Through the Body of Healthy Female Adult Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Atogepant|DRUG: Ubrogepant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lenalidomide Following Fludarabine/Rituximab (FR) in Untreated Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Rituximab|DRUG: Fludarabine|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Walking in Water and on Land in People With Chronic Obstructive Pulmonary Disease (COPD)
Status: TERMINATED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: BEHAVIORAL: Water-based walking|BEHAVIORAL: Land-based walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Probiotic Supplementation in Pregnancy to Reduce Group B Streptococcus Colonization
Status: ACTIVE_NOT_RECRUITING
Conditions: Group B Streptococcus Carrier in Childbirth
Interventions: DIETARY_SUPPLEMENT: Probiotic supplementation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Internet-Delivered Lifestyle Physical Activity Intervention for Cognitive Processing Speed in Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Behavioral Intervention for Physical Activity in MS (BIPAMS)|BEHAVIORAL: Wellness for MS (WellMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Ability Training for Seniors With Mild Cognitive Impairment
Status: WITHDRAWN
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: Verum tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Anecortave Acetate for the Treatment of Exudative Age-Related Macular Degeneration
Status: COMPLETED
Conditions: AMD
Interventions: DRUG: Anecortave acetate 30 mg|DRUG: Anecortave Acetate 15 mg|DRUG: Anecortave Acetate 3 mg|OTHER: Anecortave Acetate Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Self and Body-esteem in Socio-professional Rehabilitation
Status: UNKNOWN
Conditions: Schizophrenia|Bipolar Disorder|Personality Disorders|Anxiety Disorders|Depressive Disorder
Interventions: BEHAVIORAL: IPS program : Self-image and body representation|BEHAVIORAL: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Progesterone for the Treatment of Cocaine Dependence - 1
Status: COMPLETED
Conditions: Cocaine Abuse|Cocaine-Related Disorders
Interventions: DRUG: Progesterone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Topical 2% Ganciclovir Eye Drop for CMV Anterior Uveitis / Endotheliitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Cytomegalovirus Infections
Interventions: DRUG: 2% guttae ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of Glycemic Index of Six Greek Honey Grades
Status: COMPLETED
Conditions: Potential Abnormality of Glucose Tolerance|Appetitive Behavior
Interventions: OTHER: Glucose as reference food|OTHER: Fir honey|OTHER: Heather honey|OTHER: Citrus honey|OTHER: Pine honey|OTHER: Thyme honey|OTHER: Chestnut honey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Pilot Study on the Usefulness of 3,4-diaminopyridine in the Treatment of Botulism
Status: COMPLETED
Conditions: Botulism
Interventions: DRUG: 3,4-diaminopyridine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Bioequivalence Study of Rivaroxaban
Status: COMPLETED
Conditions: Embolism, Atrial Fibrillation and Venous Thrombosis
Interventions: DRUG: Rivaroxaban (BAY 59-7939)|DRUG: Rivaroxaban (Xarelto, BAY 59-7939)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strategy of UltraProtective Lung Ventilation With Extracorporeal CO2 Removal for New-Onset Moderate to seVere ARDS
Status: COMPLETED
Conditions: Moderate Acute Respiratory Distress Syndrome
Interventions: DEVICE: ECCO2R will be initiated during the 2-hour run-in time|OTHER: Neuromuscular blocking agents (NMBA)|DEVICE: Ventilation|OTHER: Level of carbon dioxide released at the end of expiration|OTHER: Respiratory Rate|OTHER: Sweep gas flow|OTHER: Ventilation will be adapted|OTHER: Respiratory rate will be adapted
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clonidine Added Lidocaine in Intraocular Pressure and Hemodynamics Ocular in Sub-Tenon's and Peribulbar Anesthesia
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Neurological Outcome for Acute Basilar Artery Occlusion With Sufficient Recanalization After Thrombectomy by Intraarterial Tenecteplase (INSIST-IT)
Status: RECRUITING
Conditions: Stroke, Ischemic
Interventions: DRUG: Tenecteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Loperamide for C. Difficile Colitis and Other Diarrheal Diseases Associated With Antibiotic Therapy
Status: SUSPENDED
Conditions: Antibiotic-Associated Diarrhea|Clostridium Difficile
Interventions: DRUG: loperamide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Non-invasive Neuromodulation for Intestinal Transit in Healthy Subjects
Status: NOT_YET_RECRUITING
Conditions: Constipation
Interventions: DEVICE: Non-Invasive Neuromodulation NESA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TBR-760 in Adult Patients With Non-Functioning Pituitary Adenomas
Status: UNKNOWN
Conditions: Non-Functional Pituitary Adenoma|Pituitary Tumor, Nonfunctioning
Interventions: DRUG: TBR-760|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Dose of Sugammadex for Rapid Reversal of Profound Neuromuscular Block in Young and Elderly Patients
Status: COMPLETED
Conditions: Anesthesia Recovery Period, Neuromuscular Blockade
Interventions: DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Bendamustine Combined With Alemtuzumab in Pretreated Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell
Interventions: DRUG: Bendamustine|DRUG: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of CitraFleet (Sodium Picosulphate) as an Evacuating Treatment Prior to Colonoscopy.
Status: COMPLETED
Conditions: Subjects Undergoing a Complete Exploratory Diagnostic Colonoscopy for the First Time.
Interventions: DRUG: Sodium picosulphate, light magnesium oxide and anhydride citric acid.|DRUG: Polyethylene glycol, KCl, NaCl, sodium sulphate anhydrous and sodium bicarbonate.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study of Enteric-coated Mycophenolate Sodium Maintenance Therapy in Patients With Renal Transplant Receiving Cyclosporine Microemulsion and Steroids,
Status: COMPLETED
Conditions: Maintenance Renal Transplantation
Interventions: DRUG: Enteric-Coated Mycophenolate Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Evaluating the Safety and Efficacy of ATG-010 in Relapsed Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Relapse/Refractory Multiple Myeloma
Interventions: DRUG: ATG-010
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CENTR(AR): Lungs Moving
Status: COMPLETED
Conditions: Chronic Respiratory Disease|Lung Diseases|Pulmonary Disease|Chronic Obstructive Pulmonary Disease|Interstitial Lung Disease
Interventions: OTHER: Community-based PA program|OTHER: Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Clinical Effect of GSK2646264 in Cutaneous Lupus Erythematosus Subjects
Status: COMPLETED
Conditions: Lupus Erythematosus, Cutaneous
Interventions: DRUG: GSK2646264 1%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intensity-Modulated Radiation Therapy in Treating Patients With Stage I, Stage II, Stage III, or Stage IV Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: goserelin acetate|DRUG: leuprolide acetate|RADIATION: image-guided radiation therapy|RADIATION: intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study Intends to Show Bioequivalence of the Test Product and the Reference Reference Product in a Crossover Design Study Healthy Volunteers. Additionally, the Safety Profile of Test Product Compared to Reference Product Will be Evaluated.
Status: COMPLETED
Conditions: To Determine Bioequivalence Under Fed Conditions
Interventions: DRUG: Metformin and Vildagliptin 1000/50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Comparison Study of UHE-103 Cream in Subjects With Moccasin Type Tinea Pedis
Status: COMPLETED
Conditions: Tinea Pedis
Interventions: DRUG: UHE-103A1 cream|DRUG: UHE-103A2 cream|DRUG: UHE-103B cream|DRUG: UHE-103A1B cream|DRUG: UHE-103A2B cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Unconscious Reduction of Fear Through Decoded Neuro-Reinforcement
Status: RECRUITING
Conditions: Phobia
Interventions: BEHAVIORAL: Unconscious Neuro-reinforcement|BEHAVIORAL: Unconscious Neuro-reinforcement|BEHAVIORAL: Unconscious Neuro-reinforcement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Mindfulness Smartphone App to Reduce Emotional Distress in People With Cancer Waiting for Surgery
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: Staying Calm in the OR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of HEPA Air Filters on Subclinical Markers of Cardiovascular Health
Status: COMPLETED
Conditions: Endothelial Function|Oxidative Stress|Systemic Inflammation
Interventions: DEVICE: HEPA filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Percutaneous Electrical Nerve Stimulation (PENS) of the Auricle for Post Operative Pain Solution(POPS) - Cardiac Surgery
Status: COMPLETED
Conditions: Post Operative Pain|Midline Sternotomy Incision
Interventions: DEVICE: Primary Relief v 2.0
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Immunogenicity and Safety of the 2007-2008 Influenza Vaccine
Status: COMPLETED
Conditions: Influenza|Orthomyxoviridae Infections
Interventions: BIOLOGICAL: Inactivated influenza vaccine (split virion) NH 2007-2008 formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Allogenic Hematopoietic Cell Transplantation (HCT) Participants.
Status: RECRUITING
Conditions: Cytomegalovirus Infection
Interventions: BIOLOGICAL: mRNA-1647|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ocrelizumab for Preventing Clinical Multiple Sclerosis in Individuals With Radiologically Isolated Disease.
Status: TERMINATED
Conditions: Radiologically Isolated Syndrome|Multiple Sclerosis
Interventions: DRUG: Ocrelizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Foot Massage With Roles on Cancer Patients
Status: ENROLLING_BY_INVITATION
Conditions: Breast Neoplasms|Over Cancer|Foot Massage
Interventions: OTHER: Foot Massage with roller
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Lanreotide Autogel (60, 90 or 120 mg) in Acromegalic Patients
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: Lanreotide (Autogel formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Determine Weight Gain Benefits of Caloric Supplementation for NAS Infants
Status: RECRUITING
Conditions: Neonatal Abstinence Syndrome
Interventions: DIETARY_SUPPLEMENT: High-calorie formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Accelerating Motor Recovering in Patients With SMA Syndrome After Glioma Surgery by Using nrTMS
Status: RECRUITING
Conditions: Motor Cortex; Lesion|Glioma|Supplementary Motor Area Syndrome
Interventions: DEVICE: TMS stimulation treatment|DEVICE: TMS stimulation sham-treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maintenance of an Antiaggregation by Acetylsalicylic Acid, While a Extracorporeal Lithotripsy Session on a Kidney Stone is Perfomed: Comparative Unicentric Prospective Study
Status: UNKNOWN
Conditions: Renal Lithiasis|Antiplatelet|Hematoma
Interventions: OTHER: acetylsalicylic acid (below or equal to) 250 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Rheosorbilact® Solution for Infusion, in a Complex Therapy of Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Rheosorbilact®|DRUG: Ringer lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paula Method Compared to Pelvic Floor Muscle Training (PFMT), for Urinary Stress Incontinence
Status: WITHDRAWN
Conditions: Stress Urinary Incontinence|Sexual Satisfaction|Quality of Life
Interventions: BEHAVIORAL: Paula Method|BEHAVIORAL: Pelvic Floor Muscle Training (PFMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "HIIT Med Kiloene".
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity, Childhood|High Intensity Interval Training
Interventions: BEHAVIORAL: High intensity interval training (HIIT) + lifestyle intervention (TCOCT)|BEHAVIORAL: Lifestyle intervention (TCOCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Additional Benefits of Neck Exercises in Addition to Ergonomic Training in Office Workers With Neck Pain
Status: RECRUITING
Conditions: Neck Pain
Interventions: PROCEDURE: Ergonomic training|PROCEDURE: Neck Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ASPIRE: PROs & Caregiver Burden in Children With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Crisaborole|DRUG: Tacrolimus 0.03% Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shortened Course Adjuvant Radiotherapy Following TORS
Status: RECRUITING
Conditions: HPV-Associated Oropharyngeal Squamous Cell Carcinoma
Interventions: RADIATION: Shortened Course Adjuvant Radiotherapy Following TORS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Lung Recruitment and Positive End- Expiratory Pressure (PEEP) on Anesthesia Induced Atelectasis Using Lung Ultrasound
Status: COMPLETED
Conditions: Anesthesia Induced Atelectasis
Interventions: PROCEDURE: lung recruitment maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Supplemental Transcranial Magnetic Stimulation (TMS) vs. Standard Medication Monotherapy for Treating Major Depression: An Exploratory Field Study
Status: WITHDRAWN
Conditions: 1. Major Depressive Disorder
Interventions: DEVICE: Supplemental TMS|DRUG: Standard Medication Monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Pain Therapy in HIV Neuropathy
Status: TERMINATED
Conditions: HIV Infections|Peripheral Neuropathy
Interventions: DRUG: Duloxetine|DRUG: Duloxetine placebo|DRUG: Methadone|DRUG: Methadone placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Antiretroviral Activity and Pharmacokinetics of Deferiprone in Healthy Volunteers and Asymptomatic HIV-infected Subjects
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Deferiprone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: VX15/2503 in Combination With Avelumab in Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: VX15/2503 + avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Safety and Performance of the easyEndoTM Universal Linear Cutting Stapler in Laparoscopic Gastric Bypass Surgery
Status: COMPLETED
Conditions: Roux-en-Y Gastric Bypass|Obesity
Interventions: DEVICE: easyEndoTM Universal Linear Cutting Stapler and reloads (Ezisurg Medical)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Induction of Donor Specific Tolerance in Recipients of Cardiac Allografts by Donor Stem Cell Infusion
Status: COMPLETED
Conditions: Heart Transplantation
Interventions: BIOLOGICAL: enriched hematopoetic stem cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Adalimumab in Pediatric Subjects With Moderate to Severe Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: BIOLOGICAL: Adalimumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bicarbonated Ringer's Solution Versus Lactated Ringer's Solution in Patients With Septic Shock
Status: UNKNOWN
Conditions: Septic Shock|Fluid Resuscitation|Crystalloid Solution|Intensive Care Unit
Interventions: DRUG: Bicarbonated Ringer's solution|DRUG: Lactated Ringer's solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Selective Lateral Neck Dissection in Patients With Papillary Thyroid Carcinoma
Status: COMPLETED
Conditions: Thyroid Neoplasm|Lymphatic Metastasis
Interventions: PROCEDURE: prophylactic selective lateral neck dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Longitudinal Neurocognitive, Psychosocial and Health-related Quality of Life Assessment in Advanced Cancer Survivors Treated With Immunotherapy and the Efficacy of Integrative Neurocognitive Remediation Therapy
Status: RECRUITING
Conditions: Cognitive Remediation|Neuropsychology|Quality of Life|Psycho-Oncology|Cognitive Behavioral Therapy|Cancer Survivors|Immunotherapy|Cognitive Dysfunction|Psychological Distress
Interventions: BEHAVIORAL: Integrative neurocognitive remediation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using Bupivacaine Locally in the Mastectomy Drains to Control Postoperative Pain
Status: COMPLETED
Conditions: Pain, Postoperative|Breast Cancer
Interventions: DRUG: 40ml of 0.25% bupivacaine|DRUG: 40ml of 0.9% normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Recombinant Human Thrombopoietin (rhTPO) Combining Rituximab Versus High-dose Dexamethasone for Initial Treatment of Primary Immune Thrombocytopenia (ITP)
Status: WITHDRAWN
Conditions: Purpura|Idiopathic Thrombocytopenic Purpura
Interventions: DRUG: recombinant human thrombopoietin (rhTPO); rituximab|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pro-social Power Training Activity for Aging and Well-being With Chronic Kidney Disease
Status: NOT_YET_RECRUITING
Conditions: Lower Extremity Muscle Strength
Interventions: BEHAVIORAL: Pro-social Power training Activity for Aging and Well-being with Chronic Kidney Disease|BEHAVIORAL: Attention Control for Pro-social Power training Activity for Aging and Well-being with Chronic Kidney Disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Home-based Pulmonary Rehabilitation for COPD Patients
Status: NOT_YET_RECRUITING
Conditions: COPD, Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Home based exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: MEDI5752 in Patients With Mature Tertiary Lymphoid Structures Solid Tumors.
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: MEDI5752
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Return to School Adaptation Programme for Children With Cancer
Status: ENROLLING_BY_INVITATION
Conditions: Childhood Cancer|ALL, Childhood|AML, Childhood|Lymphoma|Solid Tumor, Childhood
Interventions: BEHAVIORAL: training and counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vistakon Investigational Multi-purpose Contact Lens Care Solution.
Status: COMPLETED
Conditions: Contact Lens Wear
Interventions: DEVICE: Vistakon Investigational Multi-Purpose Solution II|DEVICE: ReNu MultiPlus Multi-Purpose Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effective Treatment of Shoulder Subluxation After Stroke With Modified Acupuncture of Biceps Brachii Muscle, Supraspinatus Muscle and Deltoid Muscle
Status: COMPLETED
Conditions: Shoulder Subluxation After Stroke
Interventions: PROCEDURE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Single Agent Pembrolizumab (MK-3475) Versus Single Agent Chemotherapy for Metastatic Triple Negative Breast Cancer (MK-3475-119/KEYNOTE-119)
Status: COMPLETED
Conditions: Metastatic Triple Negative Breast Cancer
Interventions: BIOLOGICAL: pembrolizumab|DRUG: capecitabine|DRUG: eribulin|DRUG: gemcitabine|DRUG: vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT