pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Open-Label Extension Study for the Long-Term Efficacy and Safety of Roxadustat in Participants With Dialysis and Non-Dialysis Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease|End Stage Renal Disease|Anemia
Interventions: DRUG: Roxadustat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Pancreatic Beta Cell Mass and Function by Positron Emission Tomography Imaging in Human Diabetes Mellitus
Status: RECRUITING
Conditions: type1diabetes|Type2diabetes|Pre Diabetes|Hyperinsulinism
Interventions: DRUG: 68Ga-exendin-4|OTHER: mixed meal test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment Patterns and Clinical Outcomes Among Patients With Advanced Renal Cell Carcinoma (aRCC) Receiving Systemic First-line (1st Line) Anti-cancer Treatment Under Daily Routine in Germany: Retrospective Medical Chart Review (RENALISTIC Study).
Status: TERMINATED
Conditions: Carcinoma, Renal Cell
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The "Quit-for-Kids" Project: to Increase Abstinence and Protect Children From Tobacco Smoke Exposure
Status: RECRUITING
Conditions: Smoking Cessation|Second Hand Tobacco Smoke
Interventions: BEHAVIORAL: Brief cessation advice (AWARD)|DRUG: Nicotine Replacement Therapy (NRT)|BEHAVIORAL: Instant messaging Support (IM)|BEHAVIORAL: Financial Incentive (FI)|BEHAVIORAL: Self-help smoking cessation booklet|BEHAVIORAL: Environmental assessment derived intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Performance of Dual- and Light-cure Bulk-fill Resin Composites
Status: COMPLETED
Conditions: Dental Caries Class II
Interventions: PROCEDURE: Fill-Up Class ӀӀ restoration|PROCEDURE: QuiXfil Class ӀӀ restoration|PROCEDURE: Tetric N-Ceram Bulk Fill Class ӀӀ restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Predictive Study of Peripheral Blood Biomarkers on Postoperative Neurocognitive Dysfunction in Elderly Frail and Non-frail Patients Undergoing Gastrointestinal Surgery
Status: NOT_YET_RECRUITING
Conditions: Perioperative Neurocognitive Disorders|Frail Elderly
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Recombinant Fusion Protein Linking Coagulation Factor IX With Albumin (rIX-FP) in Chinese Subjects With Hemophilia B Previously Treated With FIX Therapy
Status: RECRUITING
Conditions: Hemophilia B
Interventions: BIOLOGICAL: Recombinant fusion protein linking coagulation factor IX with albumin (rIX-FP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Impact of Personalized Move Goals on Physical Activity
Status: NOT_YET_RECRUITING
Conditions: Sedentary Lifestyle|Physical Activity
Interventions: BEHAVIORAL: Personalized move goals|BEHAVIORAL: Constant move goals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Physical Activity and Vitamin D on Osteoarthritic Knee Pain
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: Vitamin D3 2000IU/daily 3 months|BEHAVIORAL: PA intervention People with Osteoarthritis Walking Programme|OTHER: Placebo capsule (Vitamin D): edible oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of GlaxoSmithKline Biologicals' GSK2202083A Vaccine Administered as a Booster Dose
Status: COMPLETED
Conditions: Tetanus|Diphtheria|Haemophilus Influenzae Type b|Hepatitis B|Poliomyelitis|Acellular Pertussis|Diphtheria-Tetanus-aPertussis-Hepatitis B-Poliomyelitis-Haemophilus Influenzae Type b-Neisseria Meni
Interventions: BIOLOGICAL: GSK2202083A vaccine|BIOLOGICAL: Infanrix hexa™|BIOLOGICAL: Menjugate™|BIOLOGICAL: NeisVac-C™|BIOLOGICAL: Synflorix™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sirolimus to Treat Cowden Syndrome and Other PTEN Hamartomatous Tumor Syndromes
Status: COMPLETED
Conditions: Cowden's Disease|Hamartoma Syndrome, Multiple
Interventions: RADIATION: fludeoxyglucose F 18|DRUG: sirolimus|OTHER: Clinical Videography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combined Speech and Music-therapy on the Speech Characteristics of People With Parkinson's Disease (PD)
Status: COMPLETED
Conditions: Speech Disorders|Voice Disorders|Parkinson Disease
Interventions: BEHAVIORAL: combined speech and music therapy|BEHAVIORAL: speech therapy|BEHAVIORAL: music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genetics in the Effect of Caffeine on Fat Oxidation
Status: COMPLETED
Conditions: Genetic Predisposition|Caffeine|Fat Burn
Interventions: DIETARY_SUPPLEMENT: Acute caffeine supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assess Efficacy of of Oral Treprostinil in Patients With Symptomatic Primary or Secondary Raynaud's Phenomenon
Status: COMPLETED
Conditions: Raynaud's Phenomenon
Interventions: DRUG: oral treprostinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Kinesio Tape Application and Stretching Exercises on Calf Cramps During Pregnancy
Status: UNKNOWN
Conditions: Calf Cramps During Pregnancy
Interventions: OTHER: kinesio-tape|OTHER: stretching exercise|OTHER: instructions about dealing with calf cramps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind Placebo-Controlled Pharmacogenetic Study of Topiramate in European-American Heavy Drinkers
Status: COMPLETED
Conditions: Alcoholism|Alcohol Use Disorder (AUD)
Interventions: DRUG: Topiramate|BEHAVIORAL: Medical Management|DRUG: Inactive Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation on Surrogate Markers of Ageing, Ageing Genes, Glycemic and Metabolic Markers in North India
Status: UNKNOWN
Conditions: Vitamin D Supplementation|PreDiabetes|Aging
Interventions: DIETARY_SUPPLEMENT: Randomized control trial of vitamin D supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Methotrexate vs Placebo in Corticosteroid-dependent Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: methotrexate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of YK012
Status: RECRUITING
Conditions: Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Interventions: DRUG: YK012
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate Safety, Tolerance, Pharmacokinetics and Efficacy of Sc610 Injection for Treating Advanced Urinary System Tumors
Status: NOT_YET_RECRUITING
Conditions: Malignant Tumor of Urinary System (Disorder)
Interventions: BIOLOGICAL: Sc610 cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effects of GC4419 on Radiation Induced Oral Mucositis in Patients With Head/Neck Cancer
Status: COMPLETED
Conditions: Radiation Induced Oral Mucositis
Interventions: DRUG: Low Dose GC4419: 30mg/day|DRUG: High Dose GC4419: 90mg/day|DRUG: Placebo|RADIATION: Intensity-Modulated Radiation Therapy|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intravenous Iron Supplement for Iron Deficiency in Cardiac Transplant Recipients
Status: COMPLETED
Conditions: Heart Transplant Recipients
Interventions: DRUG: Iron Isomaltoside 1000|OTHER: Placebo: NaCl 0,9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Magnesium Sulphate as an Adjuvant to Bupivacaine in U.S Guided Quadratus Lumborum Block in Lower Abdominal Cancer Surgeries
Status: NOT_YET_RECRUITING
Conditions: QLB in Lower Abdominal Cancer Surgeries as a Post Operative Analgesia
Interventions: DRUG: Effect of adding Mg sulfate as an adjuvant to bupivacain in U/S guided QLB for postoperative analgesia in lower abdominal cancer surgeries
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Calcitriol and Dexamethasone in Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: calcitriol|DRUG: dexamethasone|GENETIC: protein expression analysis|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Light Treatment Effectiveness (LITE) Study
Status: COMPLETED
Conditions: Psoriasis|Psoriatic Plaque
Interventions: DEVICE: Daavlin 7 series 3 panel narrow band phototherapy home units|DEVICE: narrow band phototherapy clinic units
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Feasibility of Randomizing Danish Citizens Aged 65-79 Years to High-Dose Quadrivalent Influenza Vaccine vs. Standard-Dose Quadrivalent Influenza Vaccine in a Pragmatic Registry-Based Setting
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: Standard-Dose Quadrivalent Influenza Vaccine|DRUG: High-Dose Quadrivalent Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy of Periarticular Bone Structure in Patients Treated With Either Tocilizumab or Tumor Necrosis Factor Blockers
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tocilizumab|DRUG: TNF-alpha Inhibitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Behavior of S. Aureus Immune Globulin Intravenous(Human), [Altastaph] in Patients With S. Aureus Bacteremia and Continuing Fever
Status: COMPLETED
Conditions: Staphylococcal Infections
Interventions: DRUG: S. aureus Immune Globulin Intravenous (Human) 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Isolagen TherapyTM in Treatment of Interdental Papillary Insufficiency
Status: COMPLETED
Conditions: Interdental Papillary Insufficiency
Interventions: BIOLOGICAL: Autologous Human Fibroblasts (azficel-T)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simvastatin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response and Tumor-Free Margin in Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Chemotherapy Effect
Interventions: DRUG: Simvastatin 40mg|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Substudy (NCT04456582): Noninvasive Assessment of Myocardial Stiffness by 2D-SWE Ultrasound Technique (Two-dimensional Shear Wave Elastography) in Patients With Amyloidosis and Fabry Disease.
Status: UNKNOWN
Conditions: Fabry Disease|Amyloidosis
Interventions: DIAGNOSTIC_TEST: Shear-wave elastography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Toothpaste on the Reduction of Plaque and Inflammation
Status: COMPLETED
Conditions: Gingivitis|Dental Plaque
Interventions: OTHER: Amine fluoride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Listen in: Developing and Testing a Therapy Application for Patients With Speech Comprehension Deficits After Stroke.
Status: COMPLETED
Conditions: Aphasia
Interventions: BEHAVIORAL: Auditory comprehension therapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Exercise in Cancer-Related Fatigue in Women After Breast Cancer Treatment
Status: COMPLETED
Conditions: Fatigue|Breast Cancer
Interventions: OTHER: Physical Exercise|BEHAVIORAL: Therapeutic Education|OTHER: Therapeutic exercise-Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Open-labeled Study of NPO-11 in Patients Undergoing Therapeutic Upper Gastrointestinal Endoscopy
Status: COMPLETED
Conditions: Gastric Cancer|Colon Nos Polypectomy Tubular Adenoma|Gastric Adenoma
Interventions: DRUG: Menthol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Oral Probiotic Blend on Pregnancy Outcome
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus in Pregnancy
Interventions: DIETARY_SUPPLEMENT: capsule containing a probiotic blend of 5 different Lactobacilli|OTHER: capsule containing Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide, but no probiotics.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Population Pharmacokinetics of Paracetamol in Overweight and Obese Children
Status: NOT_YET_RECRUITING
Conditions: Overweight|Obesity
Interventions: BIOLOGICAL: Titration of paracetamol and its metabolites - scheme1|BIOLOGICAL: Titration of paracetamol and its metabolites - scheme 2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Real-time Intervention for Suicide Risk Reduction
Status: ACTIVE_NOT_RECRUITING
Conditions: Suicidal Ideation|Suicide Attempt
Interventions: BEHAVIORAL: Brief skills sessions plus EMI skills practice prompts|BEHAVIORAL: Ecological momentary assessment (EMA)|BEHAVIORAL: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Liraglutide on the Treatment of Coronary Artery Disease and Type 2 Diabetes
Status: COMPLETED
Conditions: Coronary Artery Disease|Diabetes Mellitus, Type 2
Interventions: DRUG: Liraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study to Evaluate FDG-PET, Breast MRI, and Breast Ultrasonography in Monitoring Tumour Responses in Patients With Locally Advanced Breast Cancer (LABC) Undergoing Neoadjuvant Chemotherapy
Status: COMPLETED
Conditions: Locally Advanced Breast Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Immunogenicity and Safety of DTPa-IPV/Hib Conjugate Vaccine (Infanrix™-IPV/Hib) Administered at 6, 10 and 14 Weeks in Healthy Indian Infants
Status: WITHDRAWN
Conditions: Diphtheria|Acellular Pertussis|Haemophilus Influenzae Type b|Tetanus|Poliomyelitis
Interventions: BIOLOGICAL: Infanrix-IPV/Hib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Moxifloxacin Versus Ceftriaxone in the Treatment of Primary Pyogenic Liver Abscess
Status: COMPLETED
Conditions: Liver Abscess
Interventions: DRUG: Moxifloxacin (Avelox)|DRUG: ceftriaxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GP Remote Consultation to Reduce Opioid Prescribing
Status: NOT_YET_RECRUITING
Conditions: Opioid Use
Interventions: BEHAVIORAL: Video message
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Impact Of An Intermittent Energy Restricted Diet On Insulin Sensitivity In Men and Women With Central Obesity
Status: COMPLETED
Conditions: Obesity, Abdominal
Interventions: BEHAVIORAL: Intermittent Energy Restriction|BEHAVIORAL: Continuous Energy Restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CIRN Pneumococcal Conjugate Vaccine 1 vs. 2 Dose Priming Study
Status: COMPLETED
Conditions: Invasive Pneumococcal Disease, Protection Against|Streptococcus Pneumoniae Infection
Interventions: BIOLOGICAL: PCV13
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Non-Incised Papilla Flap in Deep Supraossous Defects
Status: RECRUITING
Conditions: Periodontitis
Interventions: PROCEDURE: Non-incised papila surgical approach only|PROCEDURE: Non-incised papila surgical approach with connective tissue grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erythromycin in Septic Patients: Immunomodulatory Role and Clinical Impact
Status: COMPLETED
Conditions: Sepsis|Septic Shock|Immunoinflammatory Response
Interventions: DRUG: Erythromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer Disease|Alzheimer Disease 1|Alzheimer Disease 2|Alzheimer Disease 3|Alzheimer Disease 4|Alzheimer Disease 5|Alzheimer Disease 6|Alzheimer Disease 7|Alzheimer Disease 8|Alzheimer Disease 9, Late-Onset|Alzheimer Disease 10|Alzheimer Disease 11|Alzheimer Disease 12|Alzheimer Disease 13|Alzheimer Disease 14|Alzheimer Disease 15|Alzheimer Disease 16|Alzheimer Disease 17|Alzheimer Disease 18|Alzheimer Disease 19|Alzheimer Disease, Early Onset|Alzheimer Disease, Late Onset|Alzheimer Disease Focal
Interventions: OTHER: No Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adenovirus Vaccine for Malaria
Status: COMPLETED
Conditions: Plasmodium Falciparum Infection
Interventions: DRUG: Placebo|BIOLOGICAL: Ad35.CS.01 Circumsporozoite Malaria Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stereotactic Radiosurgery Prognosis Assessment for Spinal Tumors Based on Radiomics
Status: NOT_YET_RECRUITING
Conditions: Stereotactic Radiosurgery|Spinal Tumor|Radiomics|Prognosis
Interventions: OTHER: No interventions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Eletric Stimulation for Hipossalivation Induced by Radiotherapy
Status: COMPLETED
Conditions: Hyposalivation|Electric Stimulation Therapy|Head and Neck Neoplasm|Radiotherapy
Interventions: DEVICE: TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COX-2 Inhibitor Versus Glucocorticoid Versus Both Combined
Status: COMPLETED
Conditions: Rupture of Anterior Cruciate Ligament
Interventions: DRUG: parecoxib, valdecoxib, etoricoxib|DRUG: Dexamethasone|DRUG: parecoxib, valdecoxib, parecoxib and dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhanced Recovery Open Versus Laparoscopic Donor Nephrectomy
Status: COMPLETED
Conditions: Renal Transplant Donor of Left Kidney
Interventions: PROCEDURE: Laparoscopic donor nephrectomy|PROCEDURE: Open donor nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gametocytocidal and Transmission-blocking Efficacy of PQ in Combination With AL and TQ in Combination With SPAQ in Mali
Status: COMPLETED
Conditions: Malaria,Falciparum
Interventions: DRUG: Artemether-lumefantrine|DRUG: Primaquine Phosphate|DRUG: Sulphadoxine-pyrimethamine with amodiaquine|DRUG: Tafenoquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Tislelizumab in Combination With Zanidatamab as a 2nd Line in HER2-Positive Advanced Gastric Cancer in K-Umbrella Trial
Status: UNKNOWN
Conditions: HER2-positive Gastric Cancer
Interventions: DRUG: Tislelizumab+Zanidatamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Periodontal Management in Hypertensive Patients (PERIOTENSION Trial I)
Status: NOT_YET_RECRUITING
Conditions: Periodontal Diseases|Gingivitis|Hypertension
Interventions: BEHAVIORAL: electric toothbrush|PROCEDURE: Professional oral hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of a Weight Bearing and a Non-weight Bearing Protocol on Osteoporotic Women With Chronic Low Back Pain
Status: COMPLETED
Conditions: Osteoporosis|Low Back Pain
Interventions: OTHER: performing exercises in a weight bearing posture|OTHER: performing exercises in a non weight bearing posture
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Well-being Biomarkers (BIOSMILE) & Psychology Analyses in Women With Cancer After Hospital Clowns and Hosting Effects
Status: COMPLETED
Conditions: Well-Being, Psychological|Biomarkers|Cancer|Ambulatory Care|Complementary Therapies
Interventions: OTHER: Hosting conditions|OTHER: Hospital Clowns
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Health, Economic Analysis and Clinical Aspects of Patients With Neurological Disabilities in Enteral Nutrition With Dedicated Formula. The Role of Nissen's Fundoplication in the Management of Gastroesophageal Reflux
Status: UNKNOWN
Conditions: Gastro-Esophageal Reflux|Fundoplication
Interventions: PROCEDURE: Nissen fundoplication|BIOLOGICAL: Enteral nutrition
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Studying if Adding Night Compression to Standard Care Will Have Improved Control of Lymphedema in Breast Cancer Subjects
Status: COMPLETED
Conditions: Breast Cancer|Lymphedema
Interventions: DEVICE: Night-time compression bandages|DEVICE: Compression Sleeve, daytime wear|DEVICE: Night-time Compression custom-made garment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain, Recovery and Discharge Following Robot-assisted Laparoscopic Prostatectomy
Status: COMPLETED
Conditions: Radical Prostatectomy|Postoperative Pain
Interventions: DRUG: Bupivacaine|DRUG: Analgesics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use Of Nfant(R) Technology Feeding System For Infants Less Than 30 Weeks GA
Status: COMPLETED
Conditions: Prematurity|Extreme Prematurity
Interventions: DEVICE: nfant(R) feeding system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase III Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome
Status: COMPLETED
Conditions: Dry Eye With Sjögren's Syndrome
Interventions: DRUG: KCT-0809 ophthalmic solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: A Phase 3, Randomized, Three-Cycle, Double-Blind, Placebo-Controlled Study to Evaluate Induction of Secretory Conversion of Endometrium and Withdrawal Bleeding for Secondary Amenorrhea
Status: TERMINATED
Conditions: Secondary Amenorrhea
Interventions: DRUG: Progesterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Infliximab to Improve Retention of the Boston Keratoprosthesis in Patients After Stevens Johnson Syndrome/ Toxic Epidermal Necrolysis (SJS/TENS)
Status: WITHDRAWN
Conditions: Stevens-Johnson Syndrome|Corneal Blindness
Interventions: DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EEG-MRI Imaging of Methylphenidate Effects in Adult ADHD and Attentional Symptoms in Mood Disorders
Status: RECRUITING
Conditions: Adult ADHD|Adult-onset ADHD With Mood Disorder
Interventions: DRUG: Placebo|DRUG: Methylphenidate immediate release 25mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Remotely Delivered Cognitive Multisensory Rehabilitation for Sensory and Motor Recovery After Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries|Spinal Cord Diseases
Interventions: BEHAVIORAL: Remote CMR|BEHAVIORAL: Remote Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clofarabine and Melphalan Before Donor Stem Cell Transplant in Treating Patients With Myelodysplasia, Acute Leukemia in Remission, or Chronic Myelomonocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult Acute Lymphoblastic Leukemia in Remission|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Adult Acute Myeloid Leukemia in Remission|Myelodysplastic Syndrome|Secondary Myelodysplastic Syndrome|Chronic Myelomonocytic Leukemia|Therapy-Related Myelodysplastic Syndrome
Interventions: DRUG: clofarabine|DRUG: melphalan|PROCEDURE: allogeneic hematopoietic stem cell transplantation|DRUG: tacrolimus|DRUG: sirolimus|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Trial to Assess Breast Cancer Survivors and Vaginal Atrophy Treatment Outcomes
Status: SUSPENDED
Conditions: Vaginal Atrophy|Genitourinary System; Disorder, Female|Vaginal Abnormality|Sexual Dysfunction|Sexual Problem
Interventions: DEVICE: Viveve®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test How Well Different Doses of BI 765250 Are Tolerated by People With a Skin Disease Called Plaque Psoriasis
Status: RECRUITING
Conditions: Psoriasis
Interventions: DRUG: BI 765250|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics in Radiation-treated Gynecologic Cancer
Status: TERMINATED
Conditions: Gastrointestinal Toxicity|Gynecologic Cancer
Interventions: DIETARY_SUPPLEMENT: Capsules placebo|DIETARY_SUPPLEMENT: Capsules probiotic powder and corn starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Deoxycholic Acid Injection Submental Fat (SMF) Magnetic Resonance Imaging (MRI) and Subject-reported Outcome Measures Study
Status: COMPLETED
Conditions: Moderate or Severe Submental Fullness
Interventions: DRUG: Deoxycholic acid injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Identification and Treatment Response Prediction of Antipsychotic-Related Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome X
Interventions: DRUG: amisulpride|DRUG: aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Assess The Safety And Tolerability Of Increasing Single Doses Of ATR-107 (PF-05230900) In Healthy People
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Placebo SC Injection|DRUG: ATR-107 (PF-05230900) SC Injection|DRUG: ATR-107 (PF-05230900) SC Injection|DRUG: ATR-107 (PF-05230900) SC Injection|DRUG: ATR-107 (PF-05230900) SC Injection|DRUG: ATR-107 (PF-05230900) SC Injection|DRUG: ATR-107 (PF-05230900) IV Infusion|DRUG: ATR-107 (PF-05230900) IV Infusion|DRUG: ATR-107 (PF-05230900) IV Infusion|DRUG: Placebo IV Infusion|DRUG: ATR-107 (PF-05230900) IV Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Using 3D Imaging to Optimize Bifurcation Stenting
Status: UNKNOWN
Conditions: Coronary Artery Disease|Bifurcation Lesion
Interventions: DEVICE: 3D OFDI guidance arm|DEVICE: Angio guidance arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Diagnostic Tests for MASLD in Pediatric Population
Status: RECRUITING
Conditions: Metabolic Dysfunction Associated Steatotic Liver Disease|Non-Alcoholic Fatty Liver Disease (NAFLD)
Interventions: DIAGNOSTIC_TEST: Velacur|DIAGNOSTIC_TEST: MRI|DIAGNOSTIC_TEST: Blood sample collection for biomarkers|DIAGNOSTIC_TEST: Liver biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Periodontal Phenotype Study (Tooth Extraction)
Status: COMPLETED
Conditions: Tooth Extraction Status Nos
Interventions: OTHER: consent|OTHER: Screening|OTHER: Xray|OTHER: PVS Impressions|OTHER: Photographs|OTHER: CBCT|OTHER: Anesthesia|PROCEDURE: Extraction|OTHER: Clinical measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigational Immuno-therapy Study for Safety of Nivolumab in Combination With Ipilimumab to Treat Advanced Cancers
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Nivolumab in combination with Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is the Degree of Perceived Effort During Resistance Exercise Important for Improvements in Blood Glucose
Status: RECRUITING
Conditions: PreDiabetes|Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: High-effort session|BEHAVIORAL: Low-effort session|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Detection and Intervention in Developmental Delay / Behavioral Problems in Preschool Children - PLUSS
Status: ENROLLING_BY_INVITATION
Conditions: Developmental Delay|Behavioural Problem
Interventions: BEHAVIORAL: PRIMUS parent training Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: RCT of High- vs. Standard-Calorie Formula for Methadone-Exposed Infants
Status: COMPLETED
Conditions: Neonatal Abstinence Syndrome
Interventions: OTHER: High Calorie Infant formula|OTHER: Standard Calorie Infant Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Vorinostat (MK0683, SAHA) in Combination With FDA Approved Cancer Drugs in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)(0683-056)
Status: TERMINATED
Conditions: Stage IIIB or IV Non-Small Cell Lung Cancer
Interventions: DRUG: vorinostat|DRUG: Comparator: paclitaxel|DRUG: Comparator: carboplatin|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Absorption, Distribution, Metabolism, and Elimination of Opevesostat (MK-5684) in Healthy Adult Male Participants (MK-5684-008)
Status: NOT_YET_RECRUITING
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: [¹⁴C]Opevesostat|DRUG: Prednisone|DRUG: Fludrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Daclatasvir and Sofosbuvir With Ribavirin in Subjects With Cirrhosis and Genotype 3 Hepatitis C Infection
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: DCV|DRUG: SOF|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Of The Effects Of Resveratrol On Endothelial Function In Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Resveratrol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Study of Ibuprofen 200 mg/5 mL Oral Suspension vs. MOMENT 200 mg Coated Tablet
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ibuprofen 200 mg/5 mL oral suspension|DRUG: MOMENT 200 mg coated tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Impact of the Administration of Fludrocortisone in Very Premature Infants
Status: COMPLETED
Conditions: Partial Mineralocorticoid Deficiency
Interventions: DRUG: Oral Fludrocortisone (enteral)|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Adenosine 2A Receptor Agonist (Regadenoson) in Patients Undergoing Lung Transplantation
Status: UNKNOWN
Conditions: Lung Transplant
Interventions: DRUG: Regadenoson infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blinded Trial of Buprenorphine or Morphine in the Treatment of the Neonatal Abstinence Syndrome
Status: COMPLETED
Conditions: Neonatal Abstinence Syndrome
Interventions: DRUG: sublingual buprenorphine|DRUG: oral morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare to the Pharmacokinetic Profile of Two Paracetamol Formulations
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Experimental paracetamol formulation|DRUG: Marketed paracetamol|DRUG: Higher dose marketed paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Improving Communication About Serious Illness
Status: COMPLETED
Conditions: Critical Illness|Chronic Disease|Terminal Care|Palliative Care|Communication|Advance Care Planning|Neoplasm Metastasis|Lung Neoplasms|Pulmonary Disease, Chronic Obstructive|Heart Failure|End Stage Liver Disease|Kidney Failure, Chronic
Interventions: BEHAVIORAL: Communication Feedback Form for Patients with Serious Illness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multipurpose Disinfecting Solution Compatibility With a Silicone Hydrogel Contact Lens
Status: COMPLETED
Conditions: Myopia|Hyperopia
Interventions: DEVICE: Silicone Hydrogel Contact Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Micafungin Prevention Study for Fungal Disease in Child Receiving Allogenic Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Neutropenia|Hematopoietic Stem Cell Transplantation|Invasive Fungal Disease
Interventions: DRUG: Micafungin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hydration Status Evaluation of Dehydrated Children With Experimental Devices
Status: COMPLETED
Conditions: Dehydration
Interventions: OTHER: Formalized clinical assessment of hydration status|OTHER: Take a measurement of body weight on calibrated scales|DEVICE: "RF wristband" hydration status measurement|OTHER: Measure capillary refill time with manual stopwatch|DEVICE: "CRT device" hydration status measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Safety Study of the Drug MM-151 in Patients With Advanced Solid Tumors Resisting Ordinary Treatment
Status: COMPLETED
Conditions: Advanced Solid Tumors|Colorectal Cancer|Squamous Cell Head and Neck Cancer|Non Small Cell Lung Cancer|Triple Negative Breast Cancer
Interventions: DRUG: MM-151|DRUG: MM-151 + irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Difluoromethylornithine (DFMO) Chemoprevention of Skin Cancer in Organ Transplant Recipients
Status: COMPLETED
Conditions: Post-solid Organ Transplant|Skin Neoplasms
Interventions: DRUG: Difluoromethylornithine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Remote Ischemic Conditioning in STEMI to Decrease Infarct Size
Status: COMPLETED
Conditions: STEMI|CAD
Interventions: PROCEDURE: Remote Ischemic conditioning|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture in the Complementary Treatment of Diabetes Mellitus Type II
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: OTHER: Laser acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolism and Pharmacokinetics of [14C]- BIBW 2992 MA2 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [14C]- BIBW 2992 MA2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Performance, Usability, and Reliability of a Novel Device for Continuous Collection of Physiological Data
Status: COMPLETED
Conditions: Healthy Normals
Interventions: DEVICE: Physiological signal monitor|DEVICE: Heart rate and heart rate variability comparison device|DEVICE: Respiration rate comparison device|OTHER: Activity classification
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: SMS Messages to Increase Child Egg Consumption, a C-rct in Nepal
Status: COMPLETED
Conditions: Dietary Habits
Interventions: BEHAVIORAL: SMS messages|BEHAVIORAL: Standard SII SBCC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Temperature Leaching Solution of Disposable Plastic Tableware on Intestinal Health of Adults
Status: ENROLLING_BY_INVITATION
Conditions: Intestinal Dysfunction|Inflammation
Interventions: OTHER: hot purified water
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Interest of Routine Screening for Hepatitis B and C in Patients Receiving Chemotherapy for Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor
Interventions: OTHER: hepatitis B virus (HBV) and hepatitis C virus (HCV) serologies and a screening questionnaire to detect risk factors of hepatitis B virus (HBV) and hepatitis C virus (HCV)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stem Cell Transplantation To Treat High Risk Multiple Myeloma With Reduced Toxicity Myeloablative Conditioning Regimen
Status: TERMINATED
Conditions: Multiple Myeloma|Plasma Cell Leukemia
Interventions: DRUG: Fludarabine/Busulfan x 4 days|PROCEDURE: stem cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extraction of Distoangular and Vertically Positioned Mandibular 3rd Molars
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Extraction of mandibular 3rd molar via Cowhorn forcep technique|PROCEDURE: Extraction of mandibular 3rd molar via conventional technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Musicotherapy in Reducing Pain Induced by Leg Ulcer Care
Status: NOT_YET_RECRUITING
Conditions: Debridement Care|Leg Ulcer|Leg Ulcers Venous|Pain
Interventions: OTHER: Musicotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vacuum Assisted Biopsy and Surgery Correlation in HER2 and TN Breast Cancer Subtypes MRI Responders After Neoadjuvant Therapy: BISUCO TRIAL
Status: COMPLETED
Conditions: Breast Cancer|Breast Biopsy
Interventions: PROCEDURE: Image guided vacuum assisted biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Long-term Effectiveness of Case Management for Patients With Rheumatoid Arthritis in Taiwan
Status: COMPLETED
Conditions: Arthritis, Rheumatoid|Case Management|Managed Care Programs
Interventions: BEHAVIORAL: Case management
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Oral vs Intravesical Analgesia for Office Bladder Botox Injections
Status: UNKNOWN
Conditions: Overactive Bladder Syndrome|Urge Incontinence|Urinary Incontinence|Detrusor Hyperreflexia|Detrusor Instability
Interventions: DRUG: Phenazopyridine|DRUG: Lidocaine 2% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Selected Exercise Program on Microcirculation and Lymphedema in Postmastectomy Patients
Status: UNKNOWN
Conditions: Mastectomy; Lymphedema
Interventions: COMBINATION_PRODUCT: Qigong exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Methotrexate, Blood Pressure and Arterial Function in Rheumatoid Arthritis
Status: RECRUITING
Conditions: Rheumatoid Arthritis|Stiffness, Aortic|Endothelial Dysfunction|Cardiovascular Risk Factor
Interventions: DRUG: Methotrexate|DRUG: Sulfasalazine|DRUG: Other DMARDs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Implementation of the Automated Erythrocytapheresis in Egyptian Sickle Cell Disease Center
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: PROCEDURE: Automated red cell exchange|PROCEDURE: Manual red cell exchange|PROCEDURE: Simple red cell transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of How Insulin Peglispro (LY2605541) and Insulin Glargine Affect the Breakdown of Fat and Sugar in Type 1 Diabetics
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: BIOLOGICAL: LY2605541|BIOLOGICAL: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE