pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Use of TPD Heat Lamp for Tennis Elbow Pain - a Randomized-controlled Trial
Status: TERMINATED
Conditions: Lateral Epicondylitis
Interventions: DEVICE: TDP© Lamp|DEVICE: Dummy TDP© Lamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Primary Chemotherapy in Patients With HER2-positive Early Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Myocet (Non-pegylated liposomal doxorubicin (NPLD))|DRUG: Paclitaxel|DRUG: Lapatinib (GW572016, Tykerb)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Additional Doses of AZX100 Drug Product Following Excision of Keloid Scars
Status: COMPLETED
Conditions: Scar Prevention|Scar Reduction
Interventions: DRUG: AZX100 Drug Product|DRUG: Placebo|DRUG: AZX100 Drug Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Post-transplantation Cyclophosphamide for Haploidentical Transplant From Maternal or Collateral Donors
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplantation
Interventions: DRUG: post-transplantation cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Experimentation With Screening for Bronchopulmonary Cancer and Primary Cardiovascular Prevention, Early Management of COPD and an Offer Exempted From Smoking Cessation
Status: NOT_YET_RECRUITING
Conditions: the Rate of Participation in Screening for PBC
Interventions: OTHER: screening for bronchopulmonary cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diagnosing Acute Onset Insufficient Intestinal Blood Flow (Bowel Ischemia) With a Novel CT Technique Called Dual-energy CT (DECT). This Observational Study Seeks to Evaluate Whether DECT Can Improve the Diagnosis of Bowel Ischemia and How the DECT Findings Correlate With Intraoperative Findings
Status: UNKNOWN
Conditions: Bowel Ischemia|Acute Bowel Ischemia / Infarction
Interventions: DIAGNOSTIC_TEST: Dual-energy CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I/II, Open-label Study to Investigate the Safety, Tolerability, PK, and Preliminary Efficacy of FB849
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: Phase Ia dose-escalation part of FB849 Monotherapy|DRUG: Phase Ib dose-expansion of FB849 monotherapy|DRUG: Phase IIb dose-escalation part of FB849 in Combination with Pembrolizumab|DRUG: Phase IIb dose-expansion part of FB849 in Combination with Pembrolizumab (Type A cancer)|DRUG: Phase IIb dose-expansion part of FB849 in Combination with Pembrolizumab (Type B cancer)|DRUG: Phase IIb dose-expansion part of FB849 in Combination with Pembrolizumab (Type C cancer)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peritoneum and Anterior Rectus Sheath Suturing and Ileostomy
Status: NOT_YET_RECRUITING
Conditions: Ileostomy - Stoma|Rectal Neoplasms
Interventions: PROCEDURE: Ileostomy with a support rod instead of the layer of peritoneum and anterior rectus sheath suturing|PROCEDURE: Ileostomy with the layer of the peritoneum and anterior rectus sheath suturing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Beer (Alcohol) on Social Cognition
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Beer (alcoholic)|OTHER: Placebo (non-alcoholic beer)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Virtual Reality Exposure Therapy in the Treatment of Alcohol Use Disorder
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder
Interventions: BEHAVIORAL: Virtual reality exposure therapy (VRET)|BEHAVIORAL: Acceptance and commitment therapy (ACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Consciousness-based Ayurveda Lifestyle Program for Improving Quality of Life in Survivors of Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer Survivors
Interventions: BEHAVIORAL: Ayurvedic lifestyle protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Regorafenib + Panitumumab for Colorectal Cancers
Status: TERMINATED
Conditions: KRAS and NRAS Wild-type Colorectal Cancer
Interventions: DRUG: regorafenib + panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Anovulatory Infertility in PCOS Patients
Status: COMPLETED
Conditions: Infertility|Polycystic Ovary Syndrome|Anovulation
Interventions: DRUG: Clomiphene citrate|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Bisoprolol Fumarate Tablet 10 mg Under Fasting Condition
Status: COMPLETED
Conditions: Fasting
Interventions: DRUG: Bisoprolol Fumarate Tablet 10 mg|DRUG: Bisoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parecoxib vs Paracetamol in the Treatment of Acute Renal Colic
Status: COMPLETED
Conditions: Acute Renal Colic|Ureteric Stone
Interventions: DRUG: Paracetamol|DRUG: Parecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Colon GVAX and Cyclophosphamide in Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: BIOLOGICAL: Colon GVAX|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MIND Diet and Cognitive Function in Adults With MCI
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Cognitive Function|Cognitive Decline
Interventions: BEHAVIORAL: MIND diet education|BEHAVIORAL: Routine follow-up and general advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ultraviolet-B Light Therapy and Allogeneic Stem Cell Transplantation in Treating Patients With Hematologic Malignancies
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: BIOLOGICAL: anti-thymocyte globulin|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: methylprednisolone|PROCEDURE: UV light therapy|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Avelumab With or Without Entinostat in Participants With Advanced Epithelial Ovarian Cancer
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Cancer
Interventions: DRUG: entinostat|DRUG: avelumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-term Extension Study of Tocilizumab (Myeloma Receptor Antibody [MRA]) in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate GLPG2222 in Ivacaftor-treated Subjects With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: GLPG2222 150 mg q.d.|DRUG: GLPG2222 300 mg q.d.|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Comparative Study of TAP-144-SR(6M) in Prostate Cancer Patients Previously Treated With Hormonal Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: TAP-144-SR(6M)|DRUG: TAP-144-SR(3M)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Ibuprofen for Delayed Onset Mulscle Soreness
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: IBU BID|DRUG: Placebo BID|DRUG: IBU TID|DRUG: Placebo TID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind, Randomized, Comparative Study of Delavirdine Mesylate (U-90152S) in Combination With Didanosine (ddI) Versus ddI Alone in HIV-1 Infected Individuals With CD4 Counts of <= 300/mm3
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Delavirdine mesylate|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pomalidomide and Dose-Adjusted EPOCH +/- Rituximab for HIV-Associated Lymphomas
Status: SUSPENDED
Conditions: Diffuse Large Cell Lymphoma|Non-Hodgkin Lymphoma|Burkitt Lymphoma|Plasmablastic Lymphoma|B-Cell Neoplasm
Interventions: DRUG: Vincristine|DRUG: Prednisone|DRUG: Doxorubicin|DRUG: Etoposide|DRUG: Pomalidomide|DRUG: Cyclophosphamide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Caffeine Blend on Reaction Time, Mental Performance and Focus in Athletic Males
Status: COMPLETED
Conditions: Mental Fatigue
Interventions: DIETARY_SUPPLEMENT: Caffeine Blend|OTHER: Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Long Term Effect of General Practitioner Education on Antibiotic Prescribing
Status: UNKNOWN
Conditions: Respiratory Tract Infections
Interventions: OTHER: Experimental: Training to antibiotic prescription|OTHER: No education on antibiotic prescription rules.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects Of Ankle Mobility Exercises And Heel Drop Training In Planter Fasciitis
Status: RECRUITING
Conditions: Planter Fasciitis|Eccentric Heel Drop Training|3-D Ankle Mobility
Interventions: OTHER: 3-D Ankle Mobility Exercises(A)|OTHER: Eccentric Heel Drop Training(B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Recombinant Human Growth Hormone on Height Velocity in Subjects With Idiopathic Short Stature
Status: COMPLETED
Conditions: Growth Disorder|Idiopathic Short Stature
Interventions: DRUG: somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atropine for Prevention of Dysrhythmias Caused by Percutaneous Ethanol Instillation for Hepatoma Therapy
Status: COMPLETED
Conditions: Arrhythmia|Respiratory Arrest
Interventions: DRUG: Atropine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Desflurane on Postopertative Cognitive Dysfunction
Status: UNKNOWN
Conditions: Postoperative Cognitive Dysfunction|Postoperative Delirium
Interventions: DRUG: Desﬂurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacist-led Intervention for Injectable HIV Treatment for Women With Health-related Social Needs
Status: RECRUITING
Conditions: Hiv
Interventions: BEHAVIORAL: Collaborative drug therapy management model|DRUG: Cabotegravir/Rilpivirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 1, Open-Label, Randomized, Cross-Over, Pharmacokinetic Study Evaluating the Effect of S-1 on Advanced Solid Tumors
Status: COMPLETED
Conditions: Tumors
Interventions: DRUG: S-1|DRUG: FT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HEALEY ALS Platform Trial - Regimen D Pridopidine
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Pridopidine|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Anorectal Manometry and 3D Manometry in Diagnosis of Functional Disorders in Children
Status: UNKNOWN
Conditions: Constipation|Children|Fecal Incontinence
Interventions: DEVICE: High-resolution anorectal manometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prevention of Post-spinal Anesthesia Hypotension in Caesarean Delivery Using Delayed Supine Positioning
Status: UNKNOWN
Conditions: Cesarean Section|Hypotension|Spinal Anaesthesia
Interventions: OTHER: sitting position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Retrospective, Non-interventional, Comparative Clinical Investigation of the Safety and Performance of 690AD and 690ADY Monofocal Intraocular Lens Implantation With Extended Patient Enrolment
Status: COMPLETED
Conditions: Cataract|Pseudophakia|Intraocular Lens Complication|Intraocular Lens Opacification
Interventions: DIAGNOSTIC_TEST: Standard of care|BEHAVIORAL: Patient satisfaction questionnare
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Insulin Pump and MDI for Pregestational Diabetes During Pregnancy
Status: TERMINATED
Conditions: Type 1 Diabetes|Type 2 Diabetes|Pregnancy
Interventions: DEVICE: insulin pump|OTHER: multiple daily insulin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer|Early Onset Colorectal Cancer|Diet Habit|Risk Reduction
Interventions: BEHAVIORAL: Semi Quantitative Food Frequency Questionnaire (SQFFQ)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Learn About the Study Medicine Called Tafamidis 61mg in People Diagnosed With Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Status: ACTIVE_NOT_RECRUITING
Conditions: Transthyretin Amyloid Cardiomyopathy
Interventions: DRUG: Tafamidis 61 milligrams
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Donor Stem Cell Transplant in Treating Older or Frail Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: filgrastim|BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: busulfan|DRUG: fludarabine phosphate|DRUG: methotrexate|DRUG: tacrolimus|PROCEDURE: nonmyeloablative allogeneic hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Cerebrospinal Fluid Dynamics to Optimize Treatment of Idiopathic Normal Pressure Hydrocephalus
Status: TERMINATED
Conditions: Hydrocephalus, Normal Pressure
Interventions: OTHER: Change in shunt opening pressure|OTHER: Simulated change in shunt opening pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Supportive Psychotherapy Through Internet-Based Teleconsultation on Psychological and Somatic Symptoms, Neutrophil-Lymphocyte Ratio, and Heart Rate Variability in Post Covid-19 Syndrome Patients
Status: COMPLETED
Conditions: Post-COVID-19 Syndrome
Interventions: BEHAVIORAL: Supportive Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of GSK Biologicals' Infanrix-IPV+Hib™ Vaccine
Status: COMPLETED
Conditions: Tetanus|Poliomyelitis|Acellular Pertussis|Diphtheria|Haemophilus Influenzae Type b
Interventions: BIOLOGICAL: Infanrix-IPV/Hib™|BIOLOGICAL: Infanrix Hib™|BIOLOGICAL: Poliorix™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Disorders of the Acute Phase Response Following Trauma and Invasive Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Acute Phase Response
Interventions: PROCEDURE: Blood draw (venipuncture or fingerstick)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of SPA100 (Fixed-dose Combination of Aliskiren/Amlodipine) in Patients With Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Aliskiren/Amlodipine 150/2.5 mg|DRUG: Aliskiren/amlodipine 150/5 mg|DRUG: Aliskiren 150 mg|DRUG: Amlodipine 2.5 mg|DRUG: Placebo of Aliskiren|DRUG: Placebo of Amlodipine|DRUG: Placebo of Aliskiren/amlodipine 150/2.5 mg|DRUG: Placebo of Aliskiren/amlodipine 150/5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Interferon-Gamma on Cavitary Pulmonary Tuberculosis in the Lungs
Status: COMPLETED
Conditions: Tuberculosis|AIDS-related Complex
Interventions: DRUG: Aerosol Interferon-Gamma|DRUG: Subcutaneous interferon-gamma|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Nocturnal Hypertension and Nocturia in African American Men
Status: WITHDRAWN
Conditions: High Blood Pressure
Interventions: DRUG: Thiazide Treatment Group|DRUG: Intensified Thiazide Treatment Group|DRUG: Combination Medication Treatment Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Catheter Insertion Technique for Ultrasound-guided Continuous Peripheral Nerve Blocks
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Proximal placement|PROCEDURE: Short axis ultrasound|PROCEDURE: Long axis|PROCEDURE: Distal placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Marketed Multifocal Contact Lenses
Status: COMPLETED
Conditions: Visual Performance
Interventions: DEVICE: Multifocal Contact Lens 1|DEVICE: Multifocal Contact Lens 2|DEVICE: Spherical Contact Lens 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Impact of Dosage Frequency of Propranolol on Sleep Patterns in Patients With Infantile Hemangiomas
Status: RECRUITING
Conditions: Infantile Hemangioma
Interventions: DRUG: Propranolol three times a day|DRUG: Propranolol twice a day|DRUG: Timolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Collaborative Double-Blind Placebo-Controlled Trial of Intravenous Ribavirin As a Treatment for Presumed Hantavirus Pulmonary Syndrome
Status: COMPLETED
Conditions: Hantavirus Pulmonary Syndrome
Interventions: DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Sipuleucel-T and Indoximod for Patients With Refractory Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Prostate Cancer
Interventions: BIOLOGICAL: Indoximod|BIOLOGICAL: Sipuleucel-T|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GM-CSF With Post-Transplant Cyclophosphamide
Status: RECRUITING
Conditions: Transplant-Related Hematologic Malignancy
Interventions: DRUG: Sargramostim|OTHER: Control Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2a Study of Efficacy and Safety of OpSCF in Moderate to Severe Atopic Dermatitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: OpSCF|BIOLOGICAL: Placebo|BIOLOGICAL: OpSCF (Open Label Extension)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study In Healthy Volunteers To Estimate The Effect Of The Active Ingredient Particle Size And Percentage Of The Excipients Used To Formulate The Capsules In The Dissolution Rate Of The Formulations In The Gastrointestinal Tract
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Palbociclib Formulation Reference|OTHER: Palbociclib Formulation Test|OTHER: Palbociclib Formulation Test|OTHER: Palbociclib Formulation Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF MULTIPLE SUBCUTANEOUS INJECTIONS OF SHR-1819 IN PATIENTS WITH MODERATE TO SEVERE ATOPIC DERMATITIS
Status: UNKNOWN
Conditions: Moderate to Severe Atopic Dermatitis
Interventions: DRUG: SHR-1819 injection or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Structural and Functional Correlates of Clinical Response to rTMS Treatment in Schizophrenia Patients With Resistant Auditory Hallucinations
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)|DEVICE: Sham Repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Galantamine for Cognitive Impairments in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: galantamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Functional Power Training in Children With Attention Deficit Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Child Mental Disorder
Interventions: OTHER: traditional strength training|OTHER: Power training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of CDFR0612 and CDFR0613 for Bowel Cleansing Before Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy Preparation|Colon Disease
Interventions: DRUG: CDFR0612|DRUG: CDFR0613|DRUG: Coolprep Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Magnetic Resonance Guidance of Implantable Cardioverter Defibrillator Implantation in Non-ischemic Dilated Cardiomyopathy
Status: RECRUITING
Conditions: Non-ischemic Dilated Cardiomyopathy
Interventions: OTHER: ICD/CRT-D implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study on the Efficacy and Safety of Semaglutide for Idiopathic Intracranial Hypertension Treatment
Status: NOT_YET_RECRUITING
Conditions: Idiopathic Intracranial Hypertension
Interventions: DRUG: Semaglutide|DIETARY_SUPPLEMENT: Low calorie diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study Comparing Ranibizumab Plus Dexamethasone Combination Therapy Versus Ranibizumab Monotherapy for Wet AMD
Status: COMPLETED
Conditions: Exudative Age-Related Macular Degeneration
Interventions: DRUG: ranibizumab and dexamethasone|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intrathecal Rituximab in Treating Patients With Recurrent CNS Lymphoma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Lymphoma
Interventions: BIOLOGICAL: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Community Interventional Trial (CITFOMIST)
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: 120 IU milk|DIETARY_SUPPLEMENT: 200 IU Milk|DIETARY_SUPPLEMENT: Non-Fortified Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Kangaroo Mother Care With Plastic Bag (Trials 2A & 2B)
Status: COMPLETED
Conditions: Preterm Infant|Hypothermia Neonatal
Interventions: OTHER: KMC & WHO protocol (0-1 hour)|OTHER: KMC, WHO protocol & bag (0-1 hour)|OTHER: KMC & WHO protocol (1-24 hours)|OTHER: KMC, WHO protocol & bag (1-24 hours)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Sirolimus for Injection (Albumin Bound) in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: Sirolimus for Injection (Albumin Bound)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3D Printing for Nodule Localization
Status: COMPLETED
Conditions: Pulmonary Nodule, Solitary|Lung Cancer
Interventions: PROCEDURE: 3D-printing guided|PROCEDURE: CT-guided|DRUG: Indocyanine Green|DRUG: Methylene blue|PROCEDURE: Preoperative|PROCEDURE: Intraoperative
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single and Multiple Ascending Dose Trial of LT-002-158 in Healthy Adult Volunteers
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteer|Hidradenitis Suppurativa|Atopic Dermatitis
Interventions: DRUG: LT-002-158/Placebo oral tablet(s)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Next DPI LABA, Multicentre, 5-way Cross-over, Adult Asthmatic Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: CHF 1535 Next DPI|DRUG: Foster BDP/Formoterol|DRUG: CHF 1535 Next DPI|DRUG: Foster BDP/Formoterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of Minnelide in Relapsed or Refractory Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Minnelide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gefitinib or Docetaxel as Second Line Therapy for Wild-type Epidermal Growth Factor Receptor (EGFR) NSCLC
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Gefitinib|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Transdermal Testosterone Patches in Surgically Menopausal Women With Low Libido
Status: COMPLETED
Conditions: Hypoactive Sexual Desire Disorder
Interventions: DRUG: Testosterone Transdermal System|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate an Immunomodulatory Therapy in Adult Patients With Perennial Allergic Rhinoconjunctivitis
Status: COMPLETED
Conditions: Perennial Allergic Rhinoconjunctivitis|House Dust Mite Allergy
Interventions: DRUG: CYT005-AllQbG10 (combination of house dust mite allergen extract with CYT003-QbG10)|DRUG: House dust mite allergen extract in combination with CYT003-QbG10-placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Persistent Cardiovascular Effects of COVID-19 Viral Infection Trial (PERCEIVE)
Status: RECRUITING
Conditions: Heart Failure
Interventions: OTHER: Heart Failure intervention (Cardiac COVID Disease Management Plan (CC-DMP)|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Phase 1 Clinical Study in Healthy Volunteers to Investigate the Drug-drug Interaction Between Multiple Doses of RO7033877 and Multiple Doses of Colistin Methanesulfonate Sodium (CMS)
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: CMS|DRUG: RO7033877|DRUG: RO7033877 + CMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Endometrial Polyps: Pathophysiology and Clinical Consequences
Status: COMPLETED
Conditions: Endometrial Polyp|Endometrial Cancer
Interventions: PROCEDURE: Hysteroscopic resection of endometrial polyps. (TCRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interactions Between TNP-2198 and Midazolam, Clarithromycin
Status: RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Midazolam|DRUG: Clarithromycin|DRUG: TNP-2198|DRUG: TNP-2198
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Genetic Determinants of the Metabolism of Non-nucleoside Reverse Transcriptase Inhibitors
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nevirapine and Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Four-Arm Randomized Control Trial of Brief MI Versus Couples-Based HIV/STI Prevention in South Africa
Status: COMPLETED
Conditions: HIV Prevention
Interventions: OTHER: Testing and Counseling|BEHAVIORAL: Brief Motivational Interview (BMI)|BEHAVIORAL: Integrated Family and Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Chondroitin Sulphate Efficay/Safety in Patients With Knee Osteoarthritis and Psoriasis
Status: COMPLETED
Conditions: Osteoarthritis|Psoriasis|Joint Diseases|Muskuloskeletal Diseases|Skin Diseases
Interventions: DRUG: Chondroitin sulphate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Trial Protocol for the Influenza Virus Vaccine (Split Virion, Inactivated) （Children Forms of Drug）
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza Virus Vaccine(no Preservative )|BIOLOGICAL: Influenza Virus Vaccine(contains Preservative)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Mirtazapine Versus Placebo in Patients With Non-small Cell Lung Cancer and Anorexia
Status: COMPLETED
Conditions: Anorexia|Non-small Cell Lung Cancer
Interventions: DRUG: Mirtazapine|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Brief MI Delivered Via Mobile Instant Messaging to Help Unmotivated Smokers With Chronic Diseases to Quit
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Brief MI intervention|BEHAVIORAL: Placebo intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Benefits and Cost-Effectiveness of a Pediatric Hospitalist Service : a Stepped Wedge Quality Improvement Trial
Status: WITHDRAWN
Conditions: Hospitalism in Children
Interventions: OTHER: Pediatric hospitalist program|OTHER: General Pediatric Inpatient Services
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Desensitizing Treatment Effects of the Laser and Ozone on Dentin Hypersensitivity: In-vivo Comparison
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: COMBINATION_PRODUCT: Gas ozone|COMBINATION_PRODUCT: Diode laser and desensitized gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Combination Biotherapy With Ipilimumab and Nivolumab or Nivolumab Alone
Status: WITHDRAWN
Conditions: Melanoma
Interventions: DRUG: Nivolumab - Arm A|DRUG: Nivolumab + Ipilimumab - Arm B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of DWP16001 in Patients With Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: T2DM (Type 2 Diabetes Mellitus)
Interventions: DRUG: DWP16001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Vs. Preoperative Chemotherapy With Surgery in the Squamous Carcinoma of Esophagus
Status: COMPLETED
Conditions: Squamous Carcinoma of Esophagus|Esophagus Disorders
Interventions: DRUG: Paclitaxel; Cisplatin; 5-Fluorouracil|DRUG: Paclitaxel; Cisplatin; 5-Fluorouracil; Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Dietary Intervention for the Treatment of Constipation in Institutionalized Older Adults. Medellín, 2023-2024.
Status: COMPLETED
Conditions: Constipation Chronic Idiopathic
Interventions: OTHER: FIBNUTRITION|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Single Injection of REGN475/SAR164877 in the Treatment of Chronic Pancreatitis Pain
Status: TERMINATED
Conditions: Abdominal Pain Upper
Interventions: DRUG: REGN475/SAR164877|DRUG: Placebo (for REGN475/SAR164877)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Povorcitinib (INCB054707) in Participants With Moderate to Severe Hidradenitis Suppurativa
Status: RECRUITING
Conditions: Hidradenitis Suppurativa (HS)
Interventions: DRUG: Povorcitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of SU011248 (Sunitinib) Given In A Continuous Daily Regimen In Patients With Advanced Renal Cell Cancer
Status: COMPLETED
Conditions: Carcinoma, Renal Cell Metastasis
Interventions: DRUG: SU011248 (sunitinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pars Plana Vitrectomy Combined With Phacoemulsification Cataract Surgery in Phakic Diabetes Retinopathy Patients
Status: COMPLETED
Conditions: Diabetic Retinopathy|Diabetic Cataract
Interventions: PROCEDURE: Pars plana vitrectomy combined with cataract surgery.|PROCEDURE: Pars plana vitrectomy with subsequent cataract surgery.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Sequential Two-Stage Dose Escalation Study to Evaluate the Safety and Efficacy of Ruxolitinib
Status: COMPLETED
Conditions: Myelomonocytic Leukemia
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep vs Moderate Neuromuscular Blockade in Day Case Laparoscopic Cholecystectomy.
Status: COMPLETED
Conditions: Muscle Relaxation
Interventions: DRUG: Rocuronium Bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Umbilical Cord Mesenchymal Stem Cell Improve Cardiac Function on ST-elevation Myocardial Infarction (STEMI) Patients
Status: NOT_YET_RECRUITING
Conditions: ST Elevation Myocardial Infarction
Interventions: BIOLOGICAL: Umbilical Cord Mesenchymal Stem Cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mojito Study (Mashed Or Just Integral Pill of TicagrelOr ? )
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Adverse Reaction to Antiplatelet Agent
Interventions: DRUG: Ticagrelor mashed pills|DRUG: Ticagrelor integral pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrated Smoking Cessation and Mood Management for ACS Patients
Status: WITHDRAWN
Conditions: Acute Coronary Syndrome|Tobacco Use
Interventions: BEHAVIORAL: Experimental: Behavioral Activation Treatment for Cardiac Smokers (BAT-CS)|BEHAVIORAL: Smoking cessation plus Health and Wellness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: MBSR Program and Evaluating Its Effectiveness on Relieving Chronic Pain in the Elderly
Status: ENROLLING_BY_INVITATION
Conditions: Chronic Pain
Interventions: OTHER: MBSR and physiotherapy|OTHER: physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of Cardiovascular Disease and Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Severe Obstructive Sleep Apnea (Apnea Hypopnea Index > 30 Events/Hour)|Hypertension
Interventions: DRUG: Losartan|DRUG: Allopurinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Double Blind Placebo Controlled Study of the Effect of Swallowed Beclomethasone Dipropionate on Inflammatory Markers in Adult Patients With Eosinophilic Esophagitis
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: Beclomethasone dipropionate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Evaluation of Organically Modified Ceramic Resin Composite Versus Bulkfill Resin in Proximal Posterior Cavities
Status: UNKNOWN
Conditions: Proximal Caries
Interventions: OTHER: GrandioSO x-tra® bulk|OTHER: Admira fusion X--tra® bulk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relugolix Pregnancy Registry: An Observational Study of the Safety of Relugolix-Containing Therapy Exposure in Pregnant Women and Their Offspring
Status: RECRUITING
Conditions: Pregnancy Related|Pregnancy Complications|Pregnancy, High Risk
Interventions: DRUG: Relugolix-Containing Product
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Use of Chemotherapy Plus Radiotherapy Plus Azidothymidine in Patients With AIDS-Related Lymph Node Cancer
Status: TERMINATED
Conditions: Lymphoma, Non-Hodgkin|HIV Infections
Interventions: DRUG: Methotrexate|DRUG: Leucovorin calcium|DRUG: Zidovudine|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Opioids and Police Safety Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid Overdose
Interventions: BEHAVIORAL: Opioids and Police Safety Occupational Risk Reduction Training (OPS)|BEHAVIORAL: Opioids and Police Safety Occupational Risk Reduction Training (COVID)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of AZD4205 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AZD4205|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study of TMC207 in Japanese Participants With Pulmonary Multi-Drug Resistant Tuberculosis (MDR-TB)
Status: COMPLETED
Conditions: Tuberculosis, Multidrug-Resistant
Interventions: DRUG: TMC207 (bedaquiline)|DRUG: Background Regimen (BR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lacunar Intervention Trial 1 (LACI-1)
Status: COMPLETED
Conditions: Cerebral Small Vessel Diseases|Cognitive Impairment|Stroke
Interventions: DRUG: isosorbide mononitrate|DRUG: cilostazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Effect of BMS-986142 on Pharmacokinetics (PK) of Probe Substrates
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: BMS-986142 200mg|DRUG: BMS Drug-drug interaction cocktail (montelukast, flurbiprofen, omeprazole, midazolam, and digoxin)|DRUG: BMS-986142 350mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Acceptability and Tolerance of an Orofacial Myofunctional Rehabilitation Pacifier in Infants
Status: NOT_YET_RECRUITING
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DEVICE: Orofacial Myofunctional Rehabilitation Pacifier
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Institutional Registry of Rare Diseases
Status: RECRUITING
Conditions: Rare Diseases|Amyloidosis|Sarcoidosis|Phacomatosis|Pheochromocytoma|Paraganglioma|Von Hippel-Lindau Disease|Immunoglobulin G4-Related Disease|Demyelinating Diseases|Inborn Errors of Metabolism|Eosinophilic Gastrointestinal Disorders|Hypertrophic Cardiomyopathy|Gaucher Disease|Congenital Adrenal Hyperplasia|Hereditary Angioedema|Pulmonary Hypertension|Wilson Disease|Vascular Anomalies|Mastocytosis|Multiple Endocrine Neoplasia|Inflammatory Bowel Diseases|Prader-Willi Syndrome|Hirschsprung Disease|Cushing Syndrome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of LAA-Closure vs Oral Anticoagulation in Patients With NVAF and Status Post Intracranial Bleeding.
Status: RECRUITING
Conditions: Atrial Fibrillation (AF)|Intracranial Bleed
Interventions: DEVICE: Percutaneous closure of the LAA (Watchman / Watchman FLX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION