pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Vision Loss Impact on Navigation in Virtual Reality
Status: RECRUITING
Conditions: Stroke, Ischemic|Quadrantanopia|Hemianopsia, Homonymous|Hemianopia, Homonymous|Hemianopia|Hemianopsia|Occipital Lobe Infarct|Visual Field Defect, Peripheral|Vision Loss Partial|Quadrantanopsia|Stroke Hemorrhagic
Interventions: OTHER: Virtual Reality Driving Task
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intravenous Magnesium for Sickle Cell Vasoocclusive Crisis
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: Intravenous Magnesium Sulfate|DRUG: Normal Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The TELO-SCOPE Study: Attenuating Telomere Attrition With Danazol. Is There Scope to Dramatically Improve Health Outcomes for Adults and Children With Pulmonary Fibrosis
Status: RECRUITING
Conditions: Pulmonary Fibrosis|Telomere Shortening|Telomere Disease|Dyskeratosis Congenita
Interventions: DRUG: Danazol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Physical Functioning and Handling of Spiolto® Respimat® in Patients With Chronic Obstructive Pulmonary Disease (COPD) Requiring Long-acting Dual Bronchodilation in Routine Clinical Practice
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Spiolto Respimat
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inter- and Intra-individual Variation in Acute Responses to Two Different Warm-up Types.
Status: WITHDRAWN
Conditions: Healthy
Interventions: BEHAVIORAL: Inter and intra-individual variation in acute responses to two different warm-up types
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Trial to Study the Effects of Two Drugs, Lycopene and Prednisolone in Patients With Oral Lichen Planus
Status: COMPLETED
Conditions: Oral Lichen Planus
Interventions: DRUG: lycopene|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MCS in the Treatment of Lower Urinary Tract Symptoms
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms|Benign Prostatic Hyperplasia
Interventions: DRUG: MCS-2 15 mg/day|DRUG: MCS-2 30 mg/day|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Oils For Frying and Endothelial Function
Status: COMPLETED
Conditions: Endothelial Dysfunction
Interventions: DIETARY_SUPPLEMENT: Olive Oil, SF, SF+DMP, SF+phenols
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the AIVARIX in Detecting Signs C 1-2 Classes of CVD
Status: NOT_YET_RECRUITING
Conditions: Chronic Venous Disease|CVD
Interventions: OTHER: to estimate Sensitivity and Specificity AIVARIX app in detecting C1 and C2 classes of CVD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of a Novel Medical Device to Facilitate Gel Instillation During Change of Long-term Urinary Catheters
Status: COMPLETED
Conditions: Urinary Catheters|Retention, Urinary|Incontinence, Urinary|Anesthesia, Local
Interventions: DEVICE: Novel gel installation device procedure|DEVICE: Standard procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Detection of SARS-CoV-2 in Follicular Fluid and Cumulus-oocyte-complexes in COVID-19 Patients
Status: COMPLETED
Conditions: Infertility|COVID|IVF
Interventions: DIAGNOSTIC_TEST: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Inhaled Interferon α2b for the Treatment of Coronavirus Disease 19 (COVID-19)
Status: COMPLETED
Conditions: Coronavirus Disease 2019
Interventions: DRUG: Interferon-Alpha2B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Neoadjuvant TCHpy（Pyrotinib ，Trastuzumab，Carboplatin and Paclitaxel）for ER+/HER2+ Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Neoadjuvant
Interventions: DRUG: pyrotinib,Trastuzumab，carboplatin，Albumin paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypertonic Resuscitation Following Traumatic Injury
Status: TERMINATED
Conditions: Shock, Traumatic
Interventions: DRUG: 7.5% hypertonic saline/6% Dextran-70 (HSD)|DRUG: 7.5% hypertonic saline (HS)|DRUG: 0.9% normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maternal Effects of Bacterial Vaginosis (BV) Treatment in Pregnancy
Status: COMPLETED
Conditions: Vaginosis, Bacterial|Premature Birth|Birth Weight|Chorioamnionitis
Interventions: DRUG: oral versus vaginal metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 68Ga-THP-PSMA PET/CT in Prostate Cancer: Clinical Stage and Restage
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: 68Ga-Labeled PSMA|DRUG: Non-labeled PSMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Dose-Response Effects of Lean Beef in a Mediterranean-Style Dietary Pattern on Cardiovascular Disease Risk Factors
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: MED 0.5|OTHER: MED 2.5|OTHER: MED 5.5|OTHER: AAD 2.5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Blood Flow Restriction and Creatine Supplementation in Women
Status: COMPLETED
Conditions: Physical Inactivity
Interventions: DIETARY_SUPPLEMENT: Creatine Monohydrate|DEVICE: Blood Flow Restriction|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Microphone Positioning on Auditory Performance in Cochlear Implant Users
Status: WITHDRAWN
Conditions: Cochlear Prosthesis Implantation
Interventions: DEVICE: Modification of active microphone positioning|BEHAVIORAL: SPHERE protocol|BEHAVIORAL: French Matrix Test|BEHAVIORAL: Quality of life questionnaire|BEHAVIORAL: Likert scale
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of tDCS on Pain in Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: DEVICE: Real-tDCS + rehabilitation programme|DEVICE: Sham-tDCS + rehabilitation programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Delgocitinib 20 mg/g Cream in Subjects With Chronic Hand Eczema
Status: COMPLETED
Conditions: Chronic Hand Eczema
Interventions: DRUG: Delgocitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Administering an HIV Vaccine in the Groin Versus the Arm
Status: COMPLETED
Conditions: HIV Infections|HIV Seronegativity
Interventions: BIOLOGICAL: ALVAC-HIV (vCP205)|BIOLOGICAL: ALVAC-HIV (vCP205)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Feasibility Study of Extended-release Naltrexone (Vivitrol) in Drug Court Settings
Status: COMPLETED
Conditions: Opioid-Related Disorders
Interventions: DRUG: Naltrexone for extended-release injectable suspension|DRUG: Oral naltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Trials of Three Non-Drug Treatments for Winter Depression (SAD)
Status: COMPLETED
Conditions: Seasonal Affective Disorder|Mood Disorders|Depression
Interventions: DEVICE: bright light box|DEVICE: dawn simulator|DEVICE: high-output negative ion generator|DEVICE: low-output negative ion generator|DEVICE: dawn light pulse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Total-Body FDG PET for Radiotherapy Response Assessment in Head and Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer
Interventions: DIAGNOSTIC_TEST: Total Body PET/CT Imagin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Shroom Tech Sport Supplementation and Concurrent Training
Status: COMPLETED
Conditions: Body Composition|Performance Measures|Hormone Profiles|Blood Lipid Profiles
Interventions: DIETARY_SUPPLEMENT: Shroom Tech Sport|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of tocilizuMAb Versus Placebo in Polymyalgia rHeumatica With glucocORticoid dEpendence SEMAPHORE
Status: COMPLETED
Conditions: Polymyalgia Rheumatica
Interventions: DRUG: Tocilizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transcranial Magnetic Stimulation for Treatment of Methamphetamine Use Disorder
Status: COMPLETED
Conditions: Amphetamine Use Disorders
Interventions: DEVICE: sham TBS|DEVICE: real mPFC cTBS|DEVICE: real dlPFC iTBS|DEVICE: real dlPFC iTBS + real mPFC cTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combining biomArkers and Tele-health Solutions for Delivering at Home and in the Community Precision Medicine for the Upper Limb in cHildren With HEMIplegia Due to Stroke
Status: NOT_YET_RECRUITING
Conditions: Congenital Hemiplegia|Unilateral Cerebral Palsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Compare MP-513 20mg & Metformin XR 1000mg FDC With Coadministration of the Two Separate Drugs
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: FDC(MP-513 20mg/Metformin XR 1000mg)|DRUG: MP-513 20mg|DRUG: Metformin XR 1000mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Peppermint Oil for the Treatment of Interstitial Cystitis / Bladder Pain Syndrome
Status: RECRUITING
Conditions: Interstitial Cystitis
Interventions: DRUG: Peppermint oil|DRUG: Coconut Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Prospective,Randomised, Open Label Study for Comparison of the Incidence and Severity of Postoperative Sore Throat (POST) Using C-MAC Video Laryngoscope and Traditional Macintosh Laryngoscope for Intubation
Status: COMPLETED
Conditions: Hoarseness of Voice|Sore-throat
Interventions: PROCEDURE: Intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Phase II Trial of Alemtuzumab and Rituximab in Patients With Previously Untreated CLL
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: Alemtuzumab|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MEV 90 of 0.5% Ropivacaine In Infraclavicular Blocks
Status: UNKNOWN
Conditions: Infraclavicular Brachial Plexus Block
Interventions: DRUG: Dose of ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of the Rivastigmine Patch on Parkinson's Disease With Memory and/or Thinking Problems
Status: COMPLETED
Conditions: Parkinsons Disease With Dementia|Parkinsons Disease With Mild to Moderate Memory and/or Thinking Problems
Interventions: DRUG: Rivastigmine Patch 9.5 cm2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study on the Pharmacodynamics of Sugammadex in Morbidly Obese Patients: Reversal of Deep Neuromuscular Blockade
Status: UNKNOWN
Conditions: Neuromuscular Blockade
Interventions: DRUG: Sugammadex|DRUG: Sugammadex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Phase 1 Trial of a Single ProHema® CB Product for Pediatric Patients With Hematologic Malignancies
Status: TERMINATED
Conditions: Hematologic Malignancies
Interventions: BIOLOGICAL: Biological: ProHema-CB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Neoadjuvant Therapy With Cisplatin Plus Mitomycin C in BRCA1-Mutated Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: PROCEDURE: chemotherapy/surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Dietary Nitrate in Dilated Cardiomyopathy
Status: COMPLETED
Conditions: Cardiomyopathy
Interventions: DIETARY_SUPPLEMENT: Dietary nitrate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase IIa: Safety, PK, & Tolerability of Sodium Nitrite in Patients With Peripheral Arterial Disease-SONIC
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DRUG: sodium nitrite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ipilumumab and Nivolumab With or Without Hypofractionated Radiotherapy in Patients With Metastatic Melanoma
Status: RECRUITING
Conditions: Metastatic Melanoma
Interventions: RADIATION: Hypofractionated Radiation Therapy (HFRT)|DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Energy Density Pulse Electromagnetic Field for Patients With Rotator Cuff Tendinopathy
Status: RECRUITING
Conditions: Rotator Cuff Tendinosis
Interventions: DEVICE: High energy density pulse electromagnetic field|DEVICE: sham High energy density pulse electromagnetic field|BEHAVIORAL: physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Esthetic Management of Anterior Teeth Utilizing Two Micro Abrasion Treatments
Status: COMPLETED
Conditions: Hypomineralization of Enamel
Interventions: OTHER: antivet|OTHER: Oplsture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quick Start of Highly Effective Contraception
Status: ACTIVE_NOT_RECRUITING
Conditions: IUD|Contraceptive Implant|Contraception|Birth Control|Emergency Contraception
Interventions: DRUG: Copper T-380 IUD|DRUG: LNG IUD|DEVICE: Contraceptive implant Nexplanon|DRUG: Depo-Provera
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Does a Safety Difference Exist Between IV Push and IV Piggyback Antibiotics?
Status: UNKNOWN
Conditions: Infection
Interventions: DEVICE: Syringe IV Push over 2-3 minutes|DEVICE: Piggyback over 30 minutes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Intranasal Ketorolac for the Acute Treatment of Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Ketorolac tromethamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral Doses of PTH134 in Post-menopausal Women
Status: COMPLETED
Conditions: Post-menopausal Osteoporosis
Interventions: DRUG: PTH134|DRUG: Placebo|DRUG: Forsteo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Investigation to Follow the Progress of Exuding Chronic Venous Leg Ulcers Using a Non-Bordered Foam Dressing
Status: RECRUITING
Conditions: Wounds|Wound of Skin|Wound Leg|Venous Leg Ulcer
Interventions: DEVICE: ALLEVYN Non-Adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reducing the Risk of Transplant Rejection: Simultaneous Kidney and Bone Marrow Transplant
Status: COMPLETED
Conditions: End-stage Renal Disease|Renal Transplantation|Kidney Transplantation
Interventions: DRUG: Conditioning Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Study of Efficacy and Recommended Dose of Kovacaine Mist for Anesthetizing Maxillary Teeth
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Kovacaine Mist 0.1 mL x 4 sprays|DRUG: Kovacaine Mist 0.2 mL x 2 sprays|DRUG: Kovacaine Mist 0.2 mL x 1 spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose Ranging Study of ART621 in Subjects Diagnosed With Rheumatoid Arthritis Taking Methotrexate
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: ART621|DRUG: ART621|DRUG: ART621|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Occlusal Adjustment as Treatment for Chronic Orofacial Pain
Status: COMPLETED
Conditions: Temporomandibular Joint Disorders|Orofacial Pain
Interventions: PROCEDURE: Occlusal adjustment|PROCEDURE: Placebo occlusal adjustment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anecortave Acetate Safety in Patients With Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-angle Glaucoma|Oular Hypertension
Interventions: DRUG: Anecortave Acetate Sterile Suspension, 30 mg/mL|DRUG: Anecortave Acetate Sterile Suspension, 60 mg/mL|DRUG: Anecortave Acetate Sterile Suspension, 75 mg/mL|OTHER: Anecortave Acetate Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bidirectional Myoelectric (BIMYO) Soft Robotic Glove Technology For Robot-Assisted Hand Therapy in Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Robot-Assisted Hand Training|OTHER: Standard Hand Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intranasal Insulin for the Treatment of HAND
Status: TERMINATED
Conditions: HIV Dementia|HIV-Associated Cognitive Motor Complex
Interventions: DRUG: Insulin, intranasal|DRUG: Placebo, intranasal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluorescence-guided Resection Of Colorectal Liver Metastases Using SGM-101 and Indocyanine GREEN
Status: RECRUITING
Conditions: Colorectal Cancer|Liver Metastasis Colon Cancer|Image
Interventions: DRUG: SGM-101 op top of ICG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Adebrelimab Combined With Bevacizumab and Albumin Paclitaxel in Non-squamous NSCLC After First-line Treatment
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Adebrelimab Combined With Bevacizumab and Albumin Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Children With Stage III or Stage IV Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: dexamethasone|DRUG: doxorubicin hydrochloride|DRUG: methotrexate|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Two Oral Drugs Combination (Cediranib and Olaparib) Compared to a Single Drug (Olaparib) for Men With Advanced Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Prostate Adenocarcinoma With Neuroendocrine Differentiation|Castration-Resistant Prostate Carcinoma|Metastatic Prostate Adenocarcinoma With Neuroendocrine Differentiation|Metastatic Prostate Carcinoma|Prostate Adenocarcinoma With Neuroendocrine Differentiation|Stage IV Prostate Adenocarcinoma AJCC v7
Interventions: DRUG: Cediranib|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PCA Ketamine-Morphine VS PCA Morphine as Post-Operative Analgesia in Colorectal Surgery
Status: COMPLETED
Conditions: Ketamine|Morphine
Interventions: DRUG: Ketamine-Morphine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Testosterone Trials in Older Men
Status: COMPLETED
Conditions: Andropause
Interventions: DRUG: AndroGel® (testosterone gel)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Lidocaine Administration in Thoracoscopic Surgery for Improved Postoperative Pain Control
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Lidocaine|DRUG: NaCl 0,9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of a Standardized Acupuncture Regimen and Amitriptyline Compared With Placebo as a Treatment for Pain Caused by Peripheral Neuropathy in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections|Peripheral Nervous System Disease
Interventions: DRUG: Amitriptyline hydrochloride|DRUG: Amitriptyline hydrochloride placebo|PROCEDURE: Point acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of BMMNC in Patients With Chronic Renal Failure
Status: UNKNOWN
Conditions: Chronic Renal Failure
Interventions: BIOLOGICAL: Intravenous transfer of Autologous (BMMNCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thoracolumbar Interfascial Plane Block in Lumber Spine Surgery
Status: RECRUITING
Conditions: Post Operative Pain Management
Interventions: PROCEDURE: Modified ultrasound guided thoracolumbar interfascial plane (TLIP) block.|PROCEDURE: Conventional ultrasound guided thoracolumbar interfascial plane (TLIP) block.|DRUG: Morphine for peritoperative analgesia (control group).|DRUG: Bupivacain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of FTO Gene Variation on Body Composition, Lipid Profile, Insulin Resistance, Advanced Glycation End-Products and Ghrelin Levels in Response to Hypocaloric, Protein Rich-Diet
Status: RECRUITING
Conditions: Obesity|Insulin Resistance|Dyslipidemias|Advance Glycation|Inflammation
Interventions: OTHER: High Protein Low Calorie Dietary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anlotinib and Irinotecan for Ewing Sarcoma
Status: UNKNOWN
Conditions: Ewing's Tumor Metastatic
Interventions: DRUG: Anlotinib|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avelumab in Previously Untreated Patients With Epithelial Ovarian Cancer (JAVELIN OVARIAN 100)
Status: TERMINATED
Conditions: Ovarian Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|DRUG: Avelumab|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of PAL Based-therapy as Initial ET Versus PAL Based-therapy After ChT for HR+/HER2- ABC
Status: UNKNOWN
Conditions: Hormone Receptor Positive Advanced Breast Cancer
Interventions: DRUG: Palbociclib based-therapy as initial endocrine therapy|DRUG: Palbociclib based-therapy after chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MRCP Diagnoses EHCC Better When Combined DWI
Status: COMPLETED
Conditions: Biliary Tract Neoplasm|Cholangiocarcinoma
Interventions: DEVICE: 3T MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial of Percutaneous Tibial Nerve Stimulation (PTNS) Versus PTNS and Fesoterodine Fumarate
Status: TERMINATED
Conditions: Overactive Bladder
Interventions: DRUG: Fesoterodine fumarate|DRUG: Placebo|PROCEDURE: Percutaneous Tibial Nerve Stimulation (PTNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of COVID-19 Vaccines Given as a Booster in Healthy Adults in Indonesia (MIACoV Indonesia)
Status: WITHDRAWN
Conditions: COVID-19
Interventions: BIOLOGICAL: Pfizer-BioNTech Standard dose|BIOLOGICAL: AstraZeneca Standard dose|BIOLOGICAL: Pfizer-BioNTech Fractional dose|BIOLOGICAL: AstraZeneca Fractional dose|BIOLOGICAL: Moderna Standard dose|BIOLOGICAL: Moderna Fractional dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Motor Imagery Technique and Mime Therapy on Facial Expressions in Facial Palsy Patients
Status: COMPLETED
Conditions: Facial Palsy
Interventions: OTHER: Motor imagery technique along with EMS|OTHER: Mime Therapy along with EMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study Comparing Taxotere Plus Curcumin Versus Taxotere Plus Placebo Combination in First-line Treatment of Prostate Cancer Metastatic Castration Resistant (CURTAXEL)
Status: TERMINATED
Conditions: Prostate Cancer Metastatic Castration Resistant
Interventions: DRUG: Curcumin|DRUG: Placebo|DRUG: Taxotere
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Healthy Infant Development Project
Status: COMPLETED
Conditions: Iron Deficiency Anemia|Iron Deficiency
Interventions: DIETARY_SUPPLEMENT: folic acid + iron prenatally, vits A & D + iron postnatally|DIETARY_SUPPLEMENT: folic acid + iron prenatally, vitamins A & D postnatally|DIETARY_SUPPLEMENT: folic acid prenatally, vitamins A & D + iron postnatally|DIETARY_SUPPLEMENT: folic acid prenatally, vitamins A & D postnatally
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Return to Work Among Cancer Survivors With Treatment-induced Survivorship Syndromes
Status: COMPLETED
Conditions: Gynecologic Cancer|Prostate Cancer|Radiation Toxicity|Malignancy|Radiotherapy Side Effect|Radiation Injuries|Cancer Survivors|Radiation Syndrome
Interventions: RADIATION: Radiotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of Isatuximab, Dexamethasone and Lenalidomide in a Go-Slow Fashion for Ultra-Frail Patients With Multiple Myeloma
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma|Plasma Cell Leukemia
Interventions: DRUG: Isatuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Therapy Versus Electrosurgery For Nasal Telangiectasias
Status: WITHDRAWN
Conditions: Telangiectasis
Interventions: DEVICE: Pulsed Dye Laser|DEVICE: Long Pulsed Alexandrite Laser|DEVICE: Pulsed Dye Laser Plus Nd:YAG Laser|PROCEDURE: Electrodesiccation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Study of Avastin Used as Adjunctive Therapy in Pterygium Surgery
Status: COMPLETED
Conditions: Pterygium
Interventions: DRUG: Bevacizumab|DRUG: Mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of an Exploratory Vehicle on Meibomian Gland Dysfunction in Patients With Demodex
Status: ACTIVE_NOT_RECRUITING
Conditions: Meibomian Gland Dysfunction|Demodex Infestation of Eyelid|Blepharitis|Demodectic Blepharitis
Interventions: DRUG: Vehicle of TP-03
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Renal Sarcoidosis by Methylprednisolone Bolus
Status: TERMINATED
Conditions: Renal Sarcoidosis
Interventions: DRUG: methylprednisolone bolus IV 15 mg/kg/d for 3 days.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ElectroNic Hydroxyurea AdhereNCE: A Strategy to Improve Hydroxyurea Adherence in Patients With Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: BEHAVIORAL: Mobile DOT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study Investigating the Concentrations of Darapladib in Blood and the Safety of This Compound in Healthy Japanese Men
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DRUG: Darapladib (SB480848)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: No Post Intubation Laryngeal Symptoms
Status: COMPLETED
Conditions: Sore-throat|Dysphonia|Dysphagia|Intubation Complication|Anesthesia Intubation Complication|Anesthesia Morbidity|Anesthesia Complication|Anesthesia; Adverse Effect|Anesthesia; Reaction|Throat Disorder|Throat; Wound|Throat Injury
Interventions: DEVICE: EndoClip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Microtransplantation to Treat Elderly Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: PROCEDURE: microtransplantation|BIOLOGICAL: HLA-mismatched donor peripheral stem cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Description of the Effectiveness, Safety, Tolerability and Adherence to Amlodipine/Atorvastatin/Perindopril Single Pill Combination Treatment in Patients With Arterial Hypertension and Dyslipidemia (TARGET)
Status: COMPLETED
Conditions: Arterial Hypertension|HTN
Interventions: DRUG: Amlodipine 5 mg + atorvastatin 10 mg + perindopril arginine 5 mg|DRUG: Amlodipine 5 mg + atorvastatin 20 mg + perindopril arginine 5 mg|DRUG: Amlodipine 5 mg + atorvastatin 20 mg + perindopril arginine 10 mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Microbiota Restoration Therapy for Recurrent Clostridium Difficile-associated Diarrhea
Status: COMPLETED
Conditions: Recurrent Clostridium Difficile Infection
Interventions: BIOLOGICAL: RBX2660 (microbiota suspension)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Ultrasound Guided Femoral 3 in 1 Block Versus Blind Fascia Iliaca Block Before Spinal Anaesthesia
Status: COMPLETED
Conditions: Regional Anaesthesia
Interventions: PROCEDURE: Fascia Iliaca Compartment Block (FICB)|PROCEDURE: 3 in 1 femoral block (FNB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ALK33-005: A Study of ALKS33 (RDC-0313) in Adults With Alcohol Dependence
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: ALKS33 (RDC-0313) (1 mg)|DRUG: ALKS33 (RDC-0313) (2.5 mg)|DRUG: ALKS33 (RDC-0313) (10 mg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Risk Evaluation and Diagnosis (Using Corus CAD or ASGES) in the Coronary Tree
Status: COMPLETED
Conditions: Coronary Artery Disease|Angina Pectoris|Chest Pain|Cardiovascular Diseases|Coronary Heart Disease|CAD|CVD|CHD
Interventions: DIAGNOSTIC_TEST: Corus CAD (ASGES)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of D3 Receptor Occupancy Using FLUORTRIOPRIDE ([18F]FTP) PET/CT
Status: ACTIVE_NOT_RECRUITING
Conditions: D3 Dopamine Receptor|Cocaine-dependent|Healthy Volunteer
Interventions: DRUG: [18F]FTP PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Vitamin D Nasal Drops in Post COVID-19 Parosmia
Status: UNKNOWN
Conditions: Parosmia
Interventions: DRUG: Vitamin D3|DRUG: Budesonide nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Two Different Approaches During Fluoroscopically Guided Interlaminar Lumbar Epidural Steroid Injection
Status: COMPLETED
Conditions: Unilateral Lumbosacral Radiculopathy Pain
Interventions: PROCEDURE: Midline vs Parasagittal Lumbar Epidural Steroid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Virtual Rehabilitation and Conventional Therapeutic Exercises in the Treatment of Individuals Post Stroke
Status: COMPLETED
Conditions: Stroke|Cerebrovascular Disorders
Interventions: OTHER: Virtual Rehabilitation|OTHER: Conventional therapeutic exercises|OTHER: Virtual Rehabilitation and Conventional Therapeutic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TMC125-TiDP2-C197: A Phase I Trial to Investigate the Pharmacokinetic Interaction Between Lopinavir/Ritonavir and TMC125 Both at Steady-state in Healthy Volunteers.
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Etravirine; Lopinavir; Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Topiramate for Treatment of Alcohol Dependence in Patients With Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder|Alcoholism|Alcohol Dependence
Interventions: DRUG: Topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of MR13A9 in Hemodialysis Patients With Pruritus.
Status: COMPLETED
Conditions: Uremic Pruritus
Interventions: DRUG: MR13A9|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nuclear Magnetic Resonance Therapy in Knee Osteoarthrosis
Status: COMPLETED
Conditions: Osteoarthrosis
Interventions: DEVICE: MRI therapy|DEVICE: MRI therapy (off)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Prohance® With Gadovist®/Gadavist™ in Magnetic Resonance Imaging (MRI) of the Brain
Status: COMPLETED
Conditions: Brain Disease
Interventions: DRUG: gadoteridol|DRUG: gadobutrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Crizotinib for ROS1 and MET Activated Lung Cancer
Status: RECRUITING
Conditions: Non-squamous Non-small-cell Lung Cancer|Stage IV Non-small Cell Lung Cancer|ROS1 Gene Rearrangement|MET Activating Mutation|MET Amplification
Interventions: DRUG: Crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasal and Bronchial Absorption Sampling in RSV Bronchiolitis
Status: COMPLETED
Conditions: Bronchiolitis|Bronchiolitis, Viral|RSV Infection|Respiratory Failure
Interventions: DIAGNOSTIC_TEST: Nasal and Bronchial Sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Web-based Pain Self-management for Adolescents With Juvenile Idiopathic Arthritis
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: BEHAVIORAL: Web-based coping skills training|BEHAVIORAL: Online disease education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Smoking Cessation Tool Based on Patient Lung CT Image
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DEVICE: Imbio Smoking Cessation Report|BEHAVIORAL: Smoking Cessation Counseling|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Edinburgh Cognitive and Behavioural Amyotrophic Lateral Sclerosis Screen in Norway: A Validation Study
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis|Cognitive Impairment
Interventions: DIAGNOSTIC_TEST: ECAS-N|DIAGNOSTIC_TEST: MoCA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: AT7519M in Treating Patients With Advanced or Metastatic Solid Tumors or Refractory Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: CDKI AT7519|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Nicotinamide Riboside on Bioenergetics and Oxidative Stress in Mild Cognitive Impairment/Alzheimer's Dementia
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Mild Alzheimer Disease
Interventions: DRUG: Nicotinamide riboside
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety Study in Retinal Transplantation for Retinitis Pigmentosa.
Status: COMPLETED
Conditions: Retinitis Pigmentosa.
Interventions: DEVICE: Retinal transplantation instrument|DEVICE: Fetal tissue.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Active Warming During General Anaesthesia on Postoperative Body Temperature, Shivering and Thermal Comfort
Status: UNKNOWN
Conditions: Nursing Caries|Postoperative Pain|Postoperative Nausea and Vomiting
Interventions: OTHER: FAW|OTHER: Warmed fluids|OTHER: Combination|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Cumulative Irritation Test of PAC-14028 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: PAC14028-Vehicle|DRUG: PAC14028-0.1|DRUG: PAC14028-0.3|DRUG: PAC14028-1.0|OTHER: Saline|OTHER: Positive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Live-streaming Vs Face-to-face Teaching Method Effectiveness in Training Surgical Clerkship
Status: RECRUITING
Conditions: Teaching Method
Interventions: OTHER: Face-to-face|OTHER: Live-streaming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of BHV-3000 (Rimegepant) Orally Disintegrating Tablet for Acute Treatment of Temporomandibular Disorders
Status: TERMINATED
Conditions: Temporomandibular Disorders (TMD)
Interventions: DRUG: Rimegepant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Assisted Approach for Total Hip Replacement and it's Effect on Functional Rehabilitation.
Status: UNKNOWN
Conditions: Total Hip Arthroplasty
Interventions: PROCEDURE: Ceramic on ceramic couple|PROCEDURE: Percutaneous assisted approach|PROCEDURE: Anterolateral approach|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rheoparin-coated Tubing System for Minimized Extracorporeal Circulation (MECC)
Status: COMPLETED
Conditions: Extracorporeal Circulation|Inflammation|Blood Coagulation|Intracranial Embolism
Interventions: DEVICE: MECC system with rheoparin coating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TLD-1, a Novel Liposomal Doxorubicin, in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: TLD-1|DRUG: Caelyx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Effect of LY2405319 After Multiple Injections in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: LY2405319|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Avelumab and Tuvusertib in Participants With Advanced Urothelial Cancer That Has Progressed on Prior Anti-PD-(L)1 Therapy (JAVELIN DDRiver Bladder)
Status: NOT_YET_RECRUITING
Conditions: Urothelial Carcinoma
Interventions: DRUG: Avelumab|DRUG: Tuvusertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Short-course Colchicine Versus Placebo After Pulmonary Vein Isolation (IMPROVE-PVI Pilot)
Status: UNKNOWN
Conditions: Atrial Fibrillation|Recurrence
Interventions: DRUG: Colchicine 0.6 mg|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examining the Effect of Acupuncture on Sleep Difficulties Related to Post Traumatic Stress Disorder
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Sleep Initiation and Maintenance Disorders
Interventions: OTHER: True group auricular acupuncture|OTHER: Sham group auricular acupuncture|OTHER: Wait-List Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT