pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Investigate the Effect of MCE on Glucose and Insulin Responses in Healthy Males
Status: COMPLETED
Conditions: Dysglycemia
Interventions: DIETARY_SUPPLEMENT: MCE|DIETARY_SUPPLEMENT: Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effects of a Cocoa Shot on the Human Brain 2
Status: COMPLETED
Conditions: Caffeine
Interventions: DIETARY_SUPPLEMENT: no caffeine|DIETARY_SUPPLEMENT: high caffeine|DIETARY_SUPPLEMENT: no theobromine|DIETARY_SUPPLEMENT: low theobromine|DIETARY_SUPPLEMENT: high theobromine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: SmartCardia for the Detection of Myocardial Ischemia in Coronary Artery Disease
Status: UNKNOWN
Conditions: Myocardial Ischemia
Interventions: DEVICE: Application of Class II A device SmartCardia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bendamustine, Carboplatin and Dexamethasone (BCD) for Refractory or Relapsed Peripheral T-cell Lymphoma
Status: COMPLETED
Conditions: T-cell Lymphoma
Interventions: DRUG: BCD chemotherapy (Bendamustine, Carboplatin, Dexamethasone)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Adult Human Mesenchymal Stem Cells to Treat Steroid Refractory Acute Graft Versus Host Disease (GVHD)
Status: COMPLETED
Conditions: Graft Versus Host Disease
Interventions: BIOLOGICAL: Prochymal®|DRUG: Placebo|DRUG: Standard of Care for GVHD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Support Software in the Planning and Real-time Monitoring of the Insertion of Needles in Interventional Magnetic Resonance Imaging (MRI): Liver Biopsy Case
Status: TERMINATED
Conditions: Liver Biopsy
Interventions: DEVICE: Planning@IFE and Standard@IFE Software|DEVICE: MR Syngo (Numaris/4) software
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Voraxaze for Delayed Methotrexate Clearance
Status: TERMINATED
Conditions: Hematologic Malignancy|Solid Tumor
Interventions: DRUG: Voraxaze (Glucarpidase)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ComCancer: Use of Let's Discuss Health Website by Patients With Prostate Cancer Undergoing Radiation Oncology Treatment
Status: RECRUITING
Conditions: Prostatic Neoplasms|Psychological Distress|Physician-Patient Relations|Communication|Patient Participation|Adherence, Treatment|Men
Interventions: BEHAVIORAL: Let's Discuss Health Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phosphate Binder-combination Study of KHK7791 in Hyperphosphatemia Patients
Status: COMPLETED
Conditions: Hyperphosphatemia
Interventions: DRUG: KHK7791|DRUG: Placebp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of MK-0653H in Japanese Participants With Hypercholesterolemia (MK-0653H-832)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Ezetimibe 10 mg|DRUG: Rosuvastatin 2.5 mg|DRUG: Placebo for Ezetimibe|DRUG: Placebo for Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study Comparing Topical, Rectal, and Oral Quetiapine
Status: COMPLETED
Conditions: Dementia|Delirium
Interventions: DRUG: Quetiapine 25 mg gel applied topically|DRUG: Quetiapine 25 mg tablet by mouth|DRUG: Quetiapine 25 mg rectal suppository|DRUG: Quetiapine 25 mg gel applied topically
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Regorafenib, With Cetuximab or Panitumumab, for the Treatment of Unresectable, Locally Advanced, or Metastatic Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: BRAF V600E Negative|KRAS Gene Mutation Negative|Locally Advanced Unresectable Colorectal Adenocarcinoma|Metastatic Colorectal Adenocarcinoma|NRAS Gene Mutation Negative|Stage III Colorectal Cancer AJCC v8|Stage IIIA Colorectal Cancer AJCC v8|Stage IIIB Colorectal Cancer AJCC v8|Stage IIIC Colorectal Cancer AJCC v8|Stage IV Colorectal Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8
Interventions: BIOLOGICAL: Cetuximab|DRUG: Irinotecan|BIOLOGICAL: Panitumumab|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Obesity on Oxalate Metabolism and Handling in Calcium Oxalate Stone Formers
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Stone
Interventions: OTHER: Controlled Diet|DIETARY_SUPPLEMENT: Carbon-13 Oxalate and Sucralose Ingestion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Decitabine Followed by Mitoxantrone Hydrochloride, Etoposide, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Previously Treated Myelodysplastic Syndrome|Recurrent Adult Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|DRUG: Decitabine|DRUG: Etoposide|OTHER: Laboratory Biomarker Analysis|DRUG: Mitoxantrone Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: G-EO Gait Rehabilitation Training in Progressive Multiple Sclerosis
Status: COMPLETED
Conditions: Progressive Multiple Sclerosis
Interventions: DEVICE: G-EO System (Reha Technology AG: Olten, Switzerland)|OTHER: Conventional Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Comparing Catheter Lock Solutions TaurolockTMHep 100 and Heparin 100 IE/ml.
Status: UNKNOWN
Conditions: Catheter-related Bloodstream Infection (CRBSI) Nos
Interventions: DEVICE: TaurolockTMHep100|DEVICE: Heparin 100 IE/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exercise Training at Ambulatory Pulmonary Rehabilitation in Idiopathic Pulmonary Fibrosis Patients
Status: UNKNOWN
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: BEHAVIORAL: Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Telerehabilitation in Individuals With Temporomandibular Joint Dysfunction and Myofascial Pain
Status: NOT_YET_RECRUITING
Conditions: Temporomandibular Joint Dysfunction|Myofascial Pain
Interventions: OTHER: Video-Conference based rehabilitation|OTHER: Home-Based rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Use of Targeted Treatment for RET Positive Advanced Non-small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Lung Non-Small Cell Carcinoma|Recurrent Lung Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: DRUG: Carboplatin|DRUG: Pemetrexed|DRUG: Selpercatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Color Stability of Sectional and Full Glass Ceramic Laminate Veneer
Status: ACTIVE_NOT_RECRUITING
Conditions: Spacing of Anterior Teeth
Interventions: PROCEDURE: Glass ceramic sectional veneer|PROCEDURE: Glass ceramic laminate veneer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Rice Fortification With Iron on Anemia Among Children
Status: COMPLETED
Conditions: Iron Deficiency Anemia
Interventions: OTHER: iron bisglycine chelate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Changes in Oral Health in Tobacco Cigarettes Smokers After Switching to Combustion-Free Nicotine Delivery Systems
Status: UNKNOWN
Conditions: Gingivitis|Periodontal Diseases
Interventions: OTHER: TOBACCO CIGARETTES|OTHER: COMBUSTION-FREE NICOTINE DELIVERY SYSTEMS (C-F NDS)|OTHER: NOT SMOKING
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Evaluation of 18F-FDOPA PET-CT in the Preoperative Initial Assessment of Medullary Thyroid Carcinoma
Status: UNKNOWN
Conditions: Medullary Thyroid Carcinoma
Interventions: OTHER: PET at 18F-FDOPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Clinical Study of SHR-A1811 in Patients With HER2 Expression / Amplification of Locally Advanced Unresectable or Recurrent Metastatic Biliary Tract Cancer
Status: RECRUITING
Conditions: HER2 Expression / Amplification in Patients With Biliary Tract Cancer
Interventions: DRUG: SHR-A1811
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Re-Evaluation of GAmma3 Intramedullary Nails in Hip Fracture (REGAIN)
Status: COMPLETED
Conditions: Femoral Neck Fractures|Intertrochanteric Fracture
Interventions: PROCEDURE: Gamma3 intramedullary nail (Stryker)|PROCEDURE: Sliding Hip Screw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Influenza Virus Vaccine, AdimFlu-S (A/H1N1), in Adults and Elders
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza A (H1N1) 2009 monovalent vaccine, inactivated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Acupressure and Reiki on Pain and Fatigue Levels
Status: COMPLETED
Conditions: Acupressure|Cancer Pain|Fatigue
Interventions: PROCEDURE: Acupressure intervention|PROCEDURE: Reiki intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Myocardial Injury in Remifentanil-based Versus Sevoflurane-sufentanil Balanced Regimens in OPCAB Surgery
Status: COMPLETED
Conditions: Ischemic Heart Disease
Interventions: DRUG: Remifentanil|DRUG: sevoflurane 1|DRUG: sevoflurane 2|DRUG: propofol|DRUG: sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Characterizing the Effect of Dopamine on Markers of Lymph Re-circulation in Fontan-associated Protein-losing Enteropathy
Status: ENROLLING_BY_INVITATION
Conditions: Dopamine|Protein-Losing Enteropathies|Lymphatic System|Lymph|Catecholamine|Single-ventricle|Congenital Heart Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevalence Of Internal Pudendal Artery Disease In Patients With Erectile Dysfunction Undergoing Diagnostic Coronary Angiography
Status: COMPLETED
Conditions: To Assess the Presence of Internal Pudendal Artery Disease in Patients With Erectile Dysfunction Undergoing Coronary Angiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Acupoint Stimulation on Lactate During Cerebral Endovascular Intervention
Status: NOT_YET_RECRUITING
Conditions: Endovascular Procedures
Interventions: OTHER: transcutaneous electrical stimulation|OTHER: electrodes attachment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strength Training and Executive Functions: A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Executive Function Disorder|Strength Training|Adolescent Behavior|Academic Achievement
Interventions: BEHAVIORAL: Strength training|BEHAVIORAL: Stretch and balance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of the Lysobact Complete Spray®, Tantum Verde® and Pharyngal® Oromucosal Spray in the Treatment of Acute Sore Throat
Status: COMPLETED
Conditions: Sore Throat
Interventions: DRUG: Lysobact Complete Sprey|DRUG: Tantum Verde® Spray|DRUG: Pharyngal® Oromucosal Spray|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vasculopathic Injury and Plasma as Endothelial Rescue in Septic Shock (SHOCK) Trial
Status: COMPLETED
Conditions: Septic Shock
Interventions: DRUG: OctaplasLG|DRUG: Ringer-Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Prebiotics on Intestinal Colonization and Mood in a University Cohort
Status: COMPLETED
Conditions: Mood
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Prebiotic supplement|DIETARY_SUPPLEMENT: Prebiotic combination|DIETARY_SUPPLEMENT: Prebiotic oligosaccharides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Epidural Analgesia or Patient-Controlled Analgesia in Treating Patients Who Have Undergone Surgery for Gynecologic Cancer
Status: COMPLETED
Conditions: Cervical Cancer|Endometrial Cancer|Fallopian Tube Cancer|Ovarian Cancer|Pain|Perioperative/Postoperative Complications|Sarcoma
Interventions: DRUG: fentanyl citrate|DRUG: hydromorphone hydrochloride|DRUG: ropivacaine hydrochloride
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Chemotherapy and Rituximab in Treating Patients With Primary Mediastinal Diffuse Large B-Cell Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: bleomycin sulfate|BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: doxorubicin hydrochloride|DRUG: etoposide phosphate|DRUG: ifosfamide|DRUG: methotrexate|DRUG: prednisolone|DRUG: prednisone|DRUG: vincristine sulfate|DRUG: vindesine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, and Activity of CM-101 in Patients With Systemic Sclerosis
Status: SUSPENDED
Conditions: Systemic Sclerosis
Interventions: DRUG: 10 mg/kg CM-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Post-operative Analgesia in Pediatric Superficial TTMPB
Status: NOT_YET_RECRUITING
Conditions: Regional Anesthesia
Interventions: PROCEDURE: Transversus Thoracic Muscle Plane Block|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Intra-articular Ozone Injections for Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis Knee
Interventions: DEVICE: Ozone gas|DRUG: Steroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Higher Infusion Parameters of IgPro20 (Hizentra) in Subjects With Primary Immunodeficiency (PID)
Status: COMPLETED
Conditions: Primary Immunodeficiency
Interventions: DRUG: IgPro20
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Pharmacokinetics of Canagliflozin/Metformin 150/1,000 mg Fixed Dose Combination
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: CANA/MET XR FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial Comparing the Efficacy and Safety of FMT in Hepatitis B Reactivation Leads to Acute on Chronic Liver Failure.
Status: COMPLETED
Conditions: Acute on Chronic Liver Failure
Interventions: DRUG: Tenofovir|DRUG: Fecal Microbiota Transplantation (FMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioavailability of Alprazolam Tablets, 2 mg
Status: COMPLETED
Conditions: Anxiety
Interventions: DRUG: Alprazolam Tablets, 2 mg (Geneva Pharmaceuticals, Inc.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Emotional Impact of Surveillance for Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer|Psychological Distress
Interventions: DIAGNOSTIC_TEST: Barratt Simplified Measure of Social Status (BSMSS)|DIAGNOSTIC_TEST: Global Assessment of Functioning scale (GAF)|DIAGNOSTIC_TEST: General Self-Efficacy Scale (GSES)|DIAGNOSTIC_TEST: Perceived Stress Scale (PSS)|DIAGNOSTIC_TEST: Coping Orientation to Problems Experienced (Brief COPE),|DIAGNOSTIC_TEST: Multidimensional Scale of Perceived Social Support (MSPSS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Innovative Multigenerational Household Intervention to Reduce Stroke and CVD
Status: COMPLETED
Conditions: Stroke|Cardiovascular Disease
Interventions: BEHAVIORAL: Motivational Interviewing Intervention Arm|OTHER: Control Brochure Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pericapsular Nerve Group (PENG) Block Versus Supra-inguinal Fascia Iliaca Compartment Block for Pain Management After Total Hip Arthroplasty: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Total Hip Arthroplasty|Postoperative Pain
Interventions: PROCEDURE: Pericapsular nerve group block|PROCEDURE: Supra-inguinal fascia iliaca compartment block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neo-Sequence 1: Neoadjuvant Chemotherapy With or Without Antiangiogenesis and Sequential Immunotherapy for HER2-negative MMR-proficient Locally Advanced Gastric or Gastroesophageal Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: SOX plus Paclitaxel with or without antiangiogenesis followed by PD-1 antibody
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PNF vs Pertubation Based Balance Training in Subacute Stroke Patients.
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: PNF(proprioceptive neuromuscular facilitation exercises)|OTHER: PBBT (pertubation based balance training)|OTHER: PNF and PBBT intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Plasma SARS-CoV-2 RNA Levels in Critically Ill COVID-19 Patients
Status: COMPLETED
Conditions: COVID-19 Pneumonia|ARDS Due to Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2
Interventions: DIAGNOSTIC_TEST: plasmatic SARS-CoV-2 RNA quantification
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Virtual Reality Therapy as a Pulmonary Rehabilitation Supporting Method
Status: COMPLETED
Conditions: Pulmonary Disease|COPD|Anxiety State|Stress|Depressive Symptoms|Mood Disorders
Interventions: BEHAVIORAL: Pulmonary rehabilitation|DEVICE: Virtual therapeutic support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ZOSTAVAX™ Safety Study in Subjects ≥ 60 Years of Age (V211-020)
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Zoster Vaccine, Live|BIOLOGICAL: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Dietary Glycemic Index on Beta-cell Function
Status: COMPLETED
Conditions: Impaired Glucose Tolerance|Oxidative Stress|Prediabetes|Impaired Fasting Glucose
Interventions: OTHER: low glycemic index (LGI) diet|OTHER: high glycemic index (HGI) diet plus placebo (PLAC)|DRUG: high glycemic index diet plus N-acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Drug-drug Interaction Study of Aggrenox and Omeprazole in Normal Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Aggrenox alone|DRUG: Aggrenox and omeprazole|DRUG: Aggrenox and omeprazole|DRUG: Omeprazole alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: p16+ Oropharyngeal Cancer Radiation Optimization Trial Reducing Elective Treatment Volumes (PROTEcT)
Status: RECRUITING
Conditions: Squamous Cell Carcinoma of the Oropharynx
Interventions: RADIATION: De-intensified chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ASP1941 in Japanese Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ASP1941|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pan-Canadian, Investigator Initiated Clinical Trial With Focal IRE Directed to Intermediate-Risk Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DEVICE: Irreversible Electroporation (NanoKnife)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Liraglutide in Individuals With Type 2 Diabetes Using Insulin
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DRUG: liraglutide|DRUG: placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Follow-up of Autologous Bone Marrow Mononuclear Cells Therapy in STEMI
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: PROCEDURE: saline infusion|PROCEDURE: autologous bone marrow mononuclear cells infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib, Gemcitabine and Nab-Paclitaxel in Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Advanced Pancreatic Cancer
Interventions: DRUG: erlotinib|DRUG: gemcitabine|DRUG: nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy Followed by Intrathecal Trastuzumab/Pertuzumab in HER2+ Breast Leptomeningeal Disease
Status: RECRUITING
Conditions: HER2-positive Breast Cancer|Leptomeningeal Metastasis|Leptomeningeal Disease
Interventions: RADIATION: Radiation Therapy|DRUG: Pertuzumab|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Followed by Denileukin Diftitox in Treating Patients With Persistent or Recurrent T-Cell Lymphoma
Status: COMPLETED
Conditions: Drug/Agent Toxicity by Tissue/Organ|Lymphoma
Interventions: BIOLOGICAL: denileukin diftitox|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Dietary Fructose on Gut Microbiota and Fecal Metabolites in Obese Men and Postmenopausal Women: A Pilot Study
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease|Obesity
Interventions: OTHER: Fructose Solution (75 Grams)|OTHER: Glucose Solution (75 grams)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: AUY922 With Lapatinib and Letrozole for ER+ HER2+ Advanced Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer|Metastatic Breast Cancer|HER-2 Positive Breast Cancer|ER Positive Breast Cancer
Interventions: DRUG: AUY922
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Crossover Study Comparing CTP-543 to Jakafi®
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CTP-543, 16 mg (2 x 8 mg tablet)|DRUG: Jakafi 15Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Closed Window vs. Open Window Technique in Management of Palatally Impacted Canines
Status: UNKNOWN
Conditions: Impacted Canine
Interventions: PROCEDURE: open window technique|PROCEDURE: closed window technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HSV G207 Alone or With a Single Radiation Dose in Children With Progressive or Recurrent Supratentorial Brain Tumors
Status: COMPLETED
Conditions: Supratentorial Neoplasms, Malignant|Malignant Glioma|Glioblastoma|Anaplastic Astrocytoma|PNET|Cerebral Primitive Neuroectodermal Tumor|Embryonal Tumor
Interventions: BIOLOGICAL: G207
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Memantine in Body Focused Repetitive Behaviors
Status: COMPLETED
Conditions: Trichotillomania (Hair-Pulling Disorder)|Dermatillomania
Interventions: DRUG: Placebo|DRUG: Memantine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Computed Tomography-guided Localization for Lung Nodules: Localization Needle Versus Coil
Status: UNKNOWN
Conditions: Lung; Node
Interventions: DEVICE: Localization needle|DEVICE: Coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of SYB Filler(SF-01) in the Correction of Nasolabial Folds
Status: COMPLETED
Conditions: Nasolabial Folds
Interventions: DEVICE: SYB Filler (SF-01)|DEVICE: Ellansé M
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of D3 on Selected Cytokines Involved in Cytokine Storm in the Covid-19 Uninfected Jordanian People
Status: COMPLETED
Conditions: Cytokine Storm
Interventions: DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Dose-ranging Study of Ramosetron for the Prevention of Nausea and Vomiting After Gynecologic Laparoscopic Surgery
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: ramosetron 0.3|DRUG: ramosetron 0.45|DRUG: ramosetron 0.6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Swallow Training With Biofeedback in Acute Post Stroke Dysphagia
Status: RECRUITING
Conditions: Dysphagia|Stroke
Interventions: OTHER: Swallow Strength and Skill Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Candida Antigen and Bivalent HPV Vaccine in the Treatment of Multiple Warts
Status: UNKNOWN
Conditions: Warts|Human Papilloma Virus
Interventions: BIOLOGICAL: Candida antigen vaccine|BIOLOGICAL: Bivalent HPV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home To Stay: a Randomized Trial Evaluating a Post-discharge Mobile App for Elective Colorectal Surgery
Status: COMPLETED
Conditions: Colorectal Cancer|Inflammatory Bowel Diseases|Utilization, Health Care|Surgery|Post Discharge Monitoring
Interventions: OTHER: Home To Stay Mobile Health Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amikacin Penetration Into the Cerebrospinal Fluid
Status: WITHDRAWN
Conditions: Gram Negative Meningitis|Post Traumatic Bacterial Meningitis
Interventions: DRUG: Systemic and Intra-Thecal Amikacin Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decompression vs. Fusion for Stable Degenerative Spondylolisthesis
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Stenosis|Spondylolisthesis
Interventions: PROCEDURE: Spinal fusion|PROCEDURE: Spinal decompression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intravitreal Bevacizumab for Threshold ROP.
Status: UNKNOWN
Conditions: Stage 2+ or Stage 3+ Retinopathy of Prematurity in Zone I or Zone II.
Interventions: PROCEDURE: Intravitreal Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pro-coagulant Markers and Anticoagulant Failure in Cancer Patients at Risk for Recurrence of Venous Thromboembolism
Status: COMPLETED
Conditions: Venous Thromboembolism|Deep-Vein Thrombosis|Pulmonary Embolism|Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness and Safety of Coronary Scoring Balloon Dilation Catheter in the Pretreatment of Coronary Stenosis Lesions
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: Coronary artery scoring balloon dilation catheter（JW Medical Systems Ltd）|DEVICE: ScoreFlex NC Coronary Dilatation Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thulium Fiber Laser (TFL) Versus Holmium MOSES Laser for Ureteroscopic Management of Kidney Stones
Status: RECRUITING
Conditions: Kidney Stone
Interventions: DEVICE: Thulium Fibre Laser|DEVICE: MOSES Holmium Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Unrelated Umbilical Cord Blood (UBC)Transplantation
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia (CML)|Acute Myelogenous Leukemia (AML)|Myelodysplastic Syndrome|Multiple Myeloma|Hodgkin Lymphoma|Non-Hodgkin Lymphoma|Chronic Lymphocytic Leukemia (CLL)|Acute Lymphocytic Leukemia (ALL)|Severe Aplastic Anemia
Interventions: GENETIC: umbilical cord blood (UCB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Lcaritin Combined With Bevacizumab and FOLFIRI in Treatment of Liver Metastases From Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Icaritin Combined With Bevacizumab and FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Trial of a Web Based App Intervention in Hormone Positive Breast Cancer Patients to Improve Adherence to Endocrine Therapy
Status: RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|HER2-Negative Breast Carcinoma|Hormone Receptor-Positive Breast Carcinoma
Interventions: OTHER: Best Practice|OTHER: Internet-Based Intervention|OTHER: Questionnaire Administration|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Instant Message-delivered Cognitive Behavioural Therapy for Insomnia (CBT-I)Stroke Caregivers
Status: RECRUITING
Conditions: Stroke|Insomnia|Depressive Symptoms|Caregiver Burnout|Psychological Distress|Mobile Phone Use
Interventions: BEHAVIORAL: iCBTI-based EMI|BEHAVIORAL: Education-based EMI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety, Tolerability and Immunogenicity Study of Different Vaccine Regimens of Trivalent Ad26.Mos.HIV or Tetravalent Ad26.Mos4.HIV Along With Clade C Glycoprotein (gp)140 in Healthy Human Immunodeficiency Virus (HIV)-Uninfected Adults
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Ad26.Mos.HIV|BIOLOGICAL: Ad26.Mos4.HIV|BIOLOGICAL: Clade C gp140|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PET/CT (Positron Emission Tomography/Computed Tomography) Imaging for Safety and Tolerability and Diagnostic Performance of BAY1075553 in Patients With Prostate Cancer and Healthy Volunteers
Status: COMPLETED
Conditions: Diagnostic Imaging
Interventions: DRUG: BAY1075553|DRUG: BAY1075553
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Use of Constant-flow Technique for Determining the Lower Inflexion Point of Pressure-volume Curve and Intrinsic PEEP During One-lung Ventilation
Status: WITHDRAWN
Conditions: One Lung Ventillation (OLV)|Two Lung Ventillation (TLV)|Positive End Expiratory Pressure (PEEP)|Zero End-expiratory Pressure (ZEEP)
Interventions: OTHER: two lung ventilation (TLV)|OTHER: one lung ventilation (OLV) without PEEP|OTHER: One lung ventilation (OLV) with positive end-expiratory pressure (PEEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Stage-based Exercise Promotion Study
Status: COMPLETED
Conditions: Obesity|Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Motivational intervention|BEHAVIORAL: Volitional intervention|BEHAVIORAL: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Peripheral Blood Stem Cell Transplant Followed by Donor Lymphocyte Infusion in Treating Older Patients With Chronic Myeloid Leukemia
Status: COMPLETED
Conditions: Accelerated Phase of Disease|Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Chronic Phase of Disease|Recurrent Disease
Interventions: DRUG: Fludarabine Phosphate|RADIATION: Total-Body Irradiation|PROCEDURE: Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation|PROCEDURE: Peripheral Blood Stem Cell Transplantation|DRUG: Cyclosporine|DRUG: Mycophenolate Mofetil|BIOLOGICAL: Therapeutic Allogeneic Lymphocytes|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exendin(9-39)Amide as a Glucagon-like Peptide-1 (GLP-1) Receptor Antagonist in Humans
Status: COMPLETED
Conditions: Hyperglycemia
Interventions: DRUG: GLP-1 control|DRUG: GLP-1 and Exendin(9-39) 300|DRUG: saline control|DRUG: GLP-1 and Exendin(9-39) 600|DRUG: GLP-1 and Exendin(9-39) 900|DRUG: GLP-1 and Exendin(9-39) 1200
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Stem Cell and Growth Factor Injury and Arthritis Clinical Research Study
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Hyaluronic Acid|DEVICE: Amniotic Tissue Allograft|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Associations of Vitamin D Deficiency and Vitamin D Receptor Polymorphisms With the Risk of Primary Open-angle Glaucoma
Status: COMPLETED
Conditions: Vitamin D Deficiency|Primary Open- Angle Glaucoma
Interventions: OTHER: Vitamin D receptor polymorphic analysis|OTHER: Serum levels of 1a, 25-Dihydroxyvitamin D3
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Understanding The Effect Of A Strong CYP3A4 Inducer On Glasdegib Pharmacokinetics
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Glasdegib|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: HIIT in Isolated IFG: A Proof-of-Concept Study
Status: NOT_YET_RECRUITING
Conditions: Isolated Impaired Fasting Glucose
Interventions: BEHAVIORAL: High-Intensity Interval Training|BEHAVIORAL: Routine dietary habits and physical activity.|DEVICE: Continuous glucose monitoring (CGM) (Dexcom G6 Pro CGM sensor)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Comparing the Injection Site Pain Experience After the Injection of Semaglutide B and Semaglutide D With 2 Different Injection Pens, a Compound for the Treatment of Type 2 Diabetes and Obesity
Status: COMPLETED
Conditions: Healthy Volunteers Diabetes Mellitus, Type 2|Healthy Volunteers Overweight|Healthy Volunteers Obesity
Interventions: DRUG: Semaglutide (administered by DV3396 pen)|DRUG: Semaglutide (administered by PDS290 pen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Latent Myofascial Trigger Points in the Craniocervical Region
Status: COMPLETED
Conditions: Myofascial Pain Syndrome
Interventions: DEVICE: Neural mobilization|DEVICE: Soft tissue techniques and Stretching|DEVICE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Enriched Yogurts With Soluble Fibre or Vegetable Protein on Satiety
Status: COMPLETED
Conditions: Overweight
Interventions: OTHER: Control Yogurt|OTHER: Yogurt Variety 1|OTHER: Yogurt Variety 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Tocotrienols for Obesity of Postmenopausal Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Postmenopausal Women
Interventions: DRUG: placebo softgel|DRUG: DeltaGold® Tocotrienol 70%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy Of Diclectin® For Nausea And Vomiting Of Pregnancy
Status: COMPLETED
Conditions: Nausea and Vomiting of Pregnancy
Interventions: DRUG: doxylamine succinate 10 mg/pyridoxine hydrochloride 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation Strategies for Task-Shifting Depression Care Depression Care in Vietnam
Status: RECRUITING
Conditions: Depression
Interventions: OTHER: Workshop Training on Multicomponent Collaborative Care for Depression|OTHER: Supervision|OTHER: Community-Engaged Learning Collaborative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Transcriptomic Study of ER 4017 Topical Application in Elderly Subject
Status: COMPLETED
Conditions: Aging
Interventions: DRUG: ER4017 (hydroxypropyltetrahydropyrantriol)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multiple Ascending Dose Study of BMS-907351 (XL184) in Patients With Solid Tumors in Japan
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: BMS-907351 (XL184)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Right Ventricular Failure in Pulmonary Arterial Hypertension (RELIEVE-PAH)
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DEVICE: V-Wave Interatrial Shunt
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esketamine Adjuvant Therapy for Patients With Chronic Visceral Pain Comorbid Major Depressive Disorder
Status: UNKNOWN
Conditions: Chronic Visceral Pain|Major Depressive Disorder
Interventions: DRUG: Pregabalin 75mg tid + Duloxetine|DRUG: Intravenous administration of esketamine 0.125 mg/kg+Duloxetine|DRUG: Intravenous administration of esketamine 0.25 mg/kg +Duloxetine|DRUG: Intravenous administration of esketamine 0.50 mg/kg+Duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Osteopathic Manipulative Treatment (OMT) on Gait Biomechanics in Parkinson's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease
Interventions: PROCEDURE: Osteopathic Manipulative Treatment (OMT)|OTHER: Light Touch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proof-of-concept Study for Bioimpedance Based Monitoring of Venous Ulcers During Galvanic Stimulation
Status: COMPLETED
Conditions: Patients With Lower Extremity Venous Ulcers|Patients With Localized Edema
Interventions: PROCEDURE: Periodical low intensity direct current (LIDC) stimulation of wound.|PROCEDURE: Compression therapy of swollen limbs.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Study of the Efficacy and Safety of Re-treatments With Rituximab in Patients With Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Anti-tnfa Therapies
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: methotrexate|DRUG: rituximab [MabThera/Rituxan]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Study Comparing the Analgesic Effects and Safety of ABT-639 Compared to Placebo in Subjects With Diabetic Neuropathic Pain
Status: COMPLETED
Conditions: Diabetic Neuropathic Pain
Interventions: DRUG: ABT-639|DRUG: pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Pharmacokinetics (PK), Safety, and Tolerability of Tigecycline in Patients 8 to 11 Years of Age
Status: COMPLETED
Conditions: Bacterial Infections|Intra-Abdominal Infection|Pneumonia, Bacterial|Skin Diseases, Bacterial|Skin Diseases, Infectious
Interventions: DRUG: Tygacil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emotional Lived in Patients Suffering From Psychogenic Nonepileptic Seizures : Study by Functional Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Psychogenic Non-epileptic Seizures
Interventions: DEVICE: fMRI (functional Magnetic Resonance Imaging)|BEHAVIORAL: psychiatric evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pembrolizumab and Exemestane/ Leuprolide in Premenopausal HR+/ HER2- Locally Advanced or Metastatic Breast Cancer
Status: TERMINATED
Conditions: Premenopausal Breast Cancer
Interventions: DRUG: Pembrolizumab/ Exemestane/ Leuprolide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panobinostat and Ruxolitinib in Primary Myelofibrosis, Post-polycythemia Vera-myelofibrosis or Post-essential Thrombocythemia-myelofibrosis
Status: COMPLETED
Conditions: Idiopathic Myelofibrosis|Post Essential Thrombocythemia Myelofibrosis|Post Polycythemia-Vera Myelofibrosis
Interventions: DRUG: panobinostat|DRUG: ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT