pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cortical Excitability Using Transcranial Magnetic Stimulation and Neuronavigation Device
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DEVICE: TMS "Magpro®, Magventure Inc" device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: EFFECT OF MEDITERRANEAN DIET ON SEXUAL FUNCTION IN WOMEN WITH METABOLIC SYNDROME
Status: COMPLETED
Conditions: Metabolic Syndrome in Women
Interventions: PROCEDURE: kegel exercise|OTHER: Mediterranean diet regimen for 12 weeks.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Collection of Case Studies in Infants With UCD to Evaluate Infant Growth and the Safety of a New Medical Food for UCD
Status: COMPLETED
Conditions: Urea Cycle Disorder|Inborn Errors of Metabolism
Interventions: OTHER: UCD Anamix Infant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)
Status: RECRUITING
Conditions: Alzheimer Disease|Dementia|Brain Diseases|Central Nervous System Diseases|Nervous System Diseases|Tauopathies|Neurodegenerative Diseases|Neurocognitive Disorders|Mental Disorders
Interventions: DRUG: Donanemab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of a Triple Combination Therapy in Subjects With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Olmesartan medoxomil|DRUG: Amlodipine|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pigtail Catheter Versus Chest Tube in the Management of Traumatic Pneumothorax
Status: UNKNOWN
Conditions: Traumatic Pneumothorax
Interventions: DEVICE: Pigtail catheter insertion (Cook)|DEVICE: chest tube (28-French)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Osteopathic Manipulation in the Management of Pain Associated With Sickel Cell Disease
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: OTHER: osteopathic manipulative therapy|OTHER: sham osteopathic manipulative therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Efficacy and Safety of Combination Therapy of Henagliflozin Proline, Retagliptin and Metformin in New Diagnosed Type 2 Diabetes Patients
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: Combination therapy|DRUG: Sequential treatment group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STIM'ZO : Examining tDCS as an add-on Treatment for Persistent Symptoms in Schizophrenia
Status: COMPLETED
Conditions: Mental Disorders|Schizophrenia
Interventions: DEVICE: Neuroconn or Neuroelectric tDCS stimulator|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dopamine Enhancement of Fear Extinction Learning in PTSD (1R21MH108753)
Status: COMPLETED
Conditions: Stress Disorder, Post Traumatic
Interventions: DRUG: Placebo|DRUG: Levodopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Tolerance of Centrifuge-induced Acceleration in Subjects With Diabetes Mellitus and Cardiac Arrhythmia
Status: COMPLETED
Conditions: Diabetes Mellitus|Arrhythmias, Cardiac
Interventions: OTHER: Centrifugation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Plasma-Induced Changes in the Metabolome Following Polyphenol Consumption
Status: COMPLETED
Conditions: Processes, Metabolic
Interventions: DIETARY_SUPPLEMENT: Tart Cherry|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Treatment Outcome of Cabergoline According to Target Prolactin Levels in Patients With Prolactinoma
Status: RECRUITING
Conditions: Pituitary Adenoma|Prolactinoma|Pituitary Tumor|Recurrence Tumor
Interventions: DRUG: Cabergoline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Long-term Ribavirin in Non-responders With Chronic Hepatitis C and Advanced Fibrosis
Status: TERMINATED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Ribavirin|DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Applied Forces During Neonatal Face Mask Ventilation With Different Face-mask Air Cushion Volumes
Status: COMPLETED
Conditions: Positive Pressure Ventilation|Preterm Infants|Apnea
Interventions: DEVICE: Partially inflated mask|DEVICE: Fully inflated mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetic Profile of an Infusion of Cilastatin in Healthy Volunteers.
Status: COMPLETED
Conditions: Dose Finding Study
Interventions: DRUG: Cilastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Process-based Therapy for Difficult-to-treat Anxiety Disorders and Depression
Status: RECRUITING
Conditions: Depression|Anxiety Disorder
Interventions: OTHER: Process-based Cognitive Behavioral Therapy (PBT)|OTHER: Cognitive Behavioral Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azacitidine and Rituximab-GDP Immunochemotherapy in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Status: UNKNOWN
Conditions: Diffuse Large B Cell Lymphoma|Relapsed Non Hodgkin Lymphoma|Refractory Non-Hodgkin Lymphoma
Interventions: DRUG: azacitidine plus R-GDP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole Milk Versus Whey Protein Supplement and Resistance Exercise
Status: COMPLETED
Conditions: Muscle Development
Interventions: DIETARY_SUPPLEMENT: Whey protein|DIETARY_SUPPLEMENT: Chocolate milk|DIETARY_SUPPLEMENT: Sugar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Smoking Cessation With the Ottawa Model and SmartCard in Out-patient Respirology Clinic Setting
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Ottawa Model with SmartCard|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant mFOLFIRINOX for High-risk Stage III Colon Cancer
Status: ENROLLING_BY_INVITATION
Conditions: Colon Cancer Stage III
Interventions: DRUG: mFOLFIRINOX|DRUG: mFOLFOX 6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OCT- Versus Angiography-guided Paclitaxel Drug-Coated Balloon Angioplasty in De Novo Coronary Artery
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: OCT-guided paclitaxel drug-coated balloon angioplasty|DEVICE: Angiography-guided paclitaxel drug-coated balloon angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Brisement Compared to Physical Therapy for the Treatment of Achilles Tendinosis
Status: WITHDRAWN
Conditions: Achilles Tendinopathy
Interventions: BIOLOGICAL: Brisement injection|PROCEDURE: Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2A Clinical Trial Evaluating the Potential Activity and Safety of hMaxi-K Gene for ED
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: hMaxi-K Single Treatment/ 2 escalating dose levels (8000 µg and 16000 µg injection)|DRUG: Placebo (PBS-20% sucrose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Mindfulness-based Intervention Versus CBT for Social Anxiety Disorder
Status: COMPLETED
Conditions: Social Anxiety Disorder
Interventions: BEHAVIORAL: Mindfulness-based Intervention|BEHAVIORAL: Cognitive Behavior Group Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incisional Hernia After Midline Versus Transverse Extraction Incision in Laparoscopic Colectomy
Status: COMPLETED
Conditions: Laparoscopic Colectomy
Interventions: PROCEDURE: laparoscopic colectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prognostic Role of the Uremic Toxin Indoxyl Sulfate on Vascular and Cardiac Functions During Acute Kidney Injury
Status: RECRUITING
Conditions: Acute Kidney Injury|Uremic; Toxemia|Vascular Dysfunction|Cardiac Dysfunction|Cardiovascular Prognosis
Interventions: OTHER: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Study of PENTAXIM™ Vaccine Versus TETRAXIM™ Vaccine Given With ACTHIB™ Vaccine in South Korean Infants.
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Poliomyelitis|Haemophilus Influenzae Type B
Interventions: BIOLOGICAL: PENTAXIM™: DTacP IPV//PRP~T combined vaccine|BIOLOGICAL: TETRAXIM™: DTacP IPV combined vaccine and ActHIB™: PRP tetanus conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Carfilzomib in Combination With Daratumumab, Lenalidomide and Dexamethasone in Transplant-ineligible NDMM Patients
Status: COMPLETED
Conditions: Myeloma Multiple|Myeloma, Plasma-Cell|Myeloma-Multiple|Plasma Cell Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Daratumumab|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Oxaliplatin Chemotherapy With or Without a Floxuridine and Dexamethasone Pump in People With Cholangiocarcinoma That Cannot Be Removed With Surgery
Status: RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Gemcitabine|DRUG: Oxaliplatin|DRUG: Dexamethasone|DRUG: Floxuridine (FUDR)|DEVICE: Implanted Medical Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SU011248 Versus Interferon-Alfa As First-Line Systemic Therapy For Patients With Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Interferon-alfa|DRUG: SU011248
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: King Vision Video Laryngoscope Ambu (aBlade) System for Use in Children
Status: COMPLETED
Conditions: Pediatric Anesthesia|King Vision Video Laryngoscope Intubation
Interventions: DEVICE: King Vision video Laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Strategies for Patients With Osteoarthritis, by Using Assistive Technology and Exercises.
Status: COMPLETED
Conditions: Osteoarthritis Hand
Interventions: DEVICE: Orthosis Exercises Orientation|BEHAVIORAL: Orientation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fitting Children With Contact Lenses
Status: COMPLETED
Conditions: Refractive Error
Interventions: DEVICE: Lotrafilcon B contact lens, investigational|DEVICE: Lotrafilcon B contact lens, commercial (AIR OPTIX AQUA)|DEVICE: Lotrafilcon B multifocal contact lens, commercial (AIR OPTIX AQUA MULTIFOCAL)|DEVICE: Contact lens care system (ClearCare)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Immunotherapy in Extensive-Stage Small-Cell Lung Cancer With Thoracic Radiotherapy
Status: RECRUITING
Conditions: Extensive-Stage Small-Cell Lung Cancer
Interventions: RADIATION: Thoracic Radiotherapy|DRUG: Etoposide with Carboplatin or Cisplatin|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Application of Coconut Oil in Oral Health
Status: ACTIVE_NOT_RECRUITING
Conditions: Periodontal Diseases|Periodontal Inflammation|Periodontal Attachment Loss|Periodontitis
Interventions: DIETARY_SUPPLEMENT: Coconut Oil|DRUG: Chlorhexidine mouthwash|OTHER: Water mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Study of Antithymocyteglobulin in Haploidentical Allogeneic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Hematopoietic Stem Cell Transplantation
Interventions: DRUG: ATG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Chronic Obstructive Pulmonary Disease Fish Oil Pilot Trial
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DIETARY_SUPPLEMENT: n-3 polyunsaturated fatty acids|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Symbicort® Turbuhaler® Versus Oxis® Turbuhaler® in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Budesonide/formoterol (Symbicort Turbuhaler)|DRUG: Formoterol (Oxis Turbuhaler)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Respiratory Rate Settings on CO2 Levels During Nasal Intermittent Positive Pressure Ventilation (NIPPV).
Status: COMPLETED
Conditions: Ventilator Lung; Newborn
Interventions: DEVICE: nasal intermittent positive pressure ventilation (NIPPV).
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LDE225 for Patients With PTCH1 or SMO Mutated Tumors
Status: TERMINATED
Conditions: PTCH1 or SMO Activated Solid and Hematologic Tumors
Interventions: DRUG: LDE225
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suppression of Daytime and Nighttime Luteinizing Hormone Frequency by Progesterone
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome|Hyperandrogenism|Normal Puberty
Interventions: DRUG: Progesterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intra-erythrocyte Dexamethasone Versus Placebo in Patients With Steroid-dependent Crohn's Disease
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COX Inhibition and Biomarkers During Neoadjuvant Chemoendocrine Therapy for ER+, HER2- Stage I-III Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer|Estrogen Receptor-positive Breast Cancer
Interventions: DRUG: Aspirin|DRUG: Tamoxifen Pill|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Online Mindfulness Intervention for People With ALS and Their Caregivers
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: BEHAVIORAL: Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Probiotics and Calcium Supplementation on Growth, Development, and Metabolic Parameters
Status: COMPLETED
Conditions: Stunting|Obesity|Cognitive Function 1, Social|Depression|Behavior|Dyslipidemias|Insulin Resistance|Permeability; Increased
Interventions: DIETARY_SUPPLEMENT: Low Calcium Milk|DIETARY_SUPPLEMENT: Regular Calcium Milk|DIETARY_SUPPLEMENT: Probiotic 1|DIETARY_SUPPLEMENT: Probiotic 2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Microsatellite Analysis of Urinary Sediment in Detecting Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: GENETIC: loss of heterozygosity analysis|GENETIC: microarray analysis|GENETIC: microsatellite instability analysis|OTHER: cytology specimen collection procedure|OTHER: laboratory biomarker analysis|PROCEDURE: computed tomography|PROCEDURE: cystoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sorafenib-induced Hand- Foot Skin Reaction Treatment
Status: TERMINATED
Conditions: Hand-foot Skin Reaction|Rash
Interventions: DRUG: urea 40% cream|DRUG: fluocinonide 0.05% cream|DRUG: tazarotene 0.1% cream|DRUG: bland emollient cream (Udderly smooth® Udder Cream)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diindolylmethane in Treating Patients With Breast Cancer
Status: COMPLETED
Conditions: Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer
Interventions: DIETARY_SUPPLEMENT: diindolylmethane|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cycloserine rTMS Plasticity Augmentation
Status: COMPLETED
Conditions: Motor Activity
Interventions: DEVICE: Transcranial Magnetic Stimulation|DRUG: Cycloserine|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I Study of Lurbinectedin (PM01183) in Combination With Paclitaxel, With or Without Bevacizumab, in Selected Advanced Solid Tumors
Status: COMPLETED
Conditions: Breast Cancer|Ovarian Cancer|Gynecological Cancer|Head and Neck Carcinoma|Non-small Cell Lung Cancer|Small Cell Lung Cancer|Non-squamous Cell Lung Cancer
Interventions: DRUG: PM01183 + paclitaxel +/- bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TRISCEND JAPAN Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Tricuspid Valve Regurgitation|Heart Valve Diseases|Cardiovascular Diseases
Interventions: DEVICE: Edwards EWJ-202 Transcatheter Tricuspid Valve Replacement System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Rosuvastatin 5 mg Versus Pravastatin 40 mg and Atorvastatin 10 mg in Type IIa and IIb Hypercholesterolaemic Patients
Status: COMPLETED
Conditions: Type IIa and IIb Hypercholesterolaemia
Interventions: DRUG: Rosuvastatin|DRUG: Pravastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Autologous Oxidized Tumor Cell Lysate Vaccine For Recurrent Ovarian, Fallopian Tube or Primary Peritoneal Cancer
Status: TERMINATED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: BIOLOGICAL: OC-L/Montanide ISA 51 VG|BIOLOGICAL: Ampligen|BIOLOGICAL: Prevnar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a High Saturated Fat Diet on Fasted Systemic and White Adipose Tissue Inflammatory Responses
Status: COMPLETED
Conditions: Inflammation|Obesity|Inflammatory Response|Cardiovascular Diseases
Interventions: OTHER: High Fat Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Prime Solution on Fluid Balance After Open Heart Surgery
Status: COMPLETED
Conditions: Valve Surgery|Coronary Artery Bypass Grafting
Interventions: DRUG: HES|DRUG: Ringer lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Reactogenicity, Safety and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Investigational Supra-seasonal Universal Influenza Vaccines - Inactivated (SUIVs) (GSK3816302A) in Healthy Adults Aged 18 to 39 Years
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: D-SUIV cH8/1N1+AS03|BIOLOGICAL: D-SUIV cH5/1N1+AS03|BIOLOGICAL: D-SUIV cH11/1N1+AS03|BIOLOGICAL: D-SUIV cH8/1N1+AS01|BIOLOGICAL: D-SUIV cH5/1N1+AS01|BIOLOGICAL: D-SUIV cH11/1N1+AS01|BIOLOGICAL: D-SUIV cH8/1N1|BIOLOGICAL: D-SUIV cH5/1N1|BIOLOGICAL: D-SUIV cH11/1N1|BIOLOGICAL: Placebo|BIOLOGICAL: Fluarix Quadrivalent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SG Healthcare and Assistive Robotics Programme (SHARP) - Proof of Concept Study
Status: COMPLETED
Conditions: Stroke|Joint Replacement Surgery|Acquired Brain Injury|Spinal Cord Injuries|Traumatic Brain Injury With Loss of Consciousness
Interventions: DEVICE: (1) Mobile Assistant Balance Robot|DEVICE: (2) Transfer Assistive Cobot
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial of 18-22mg/kg/d Ursodeoxycholic in Refractory Primary Biliary Cholangitis
Status: UNKNOWN
Conditions: Primary Biliary Cholangitis
Interventions: DRUG: 18-22mg/kg/d Ursodeoxycholic|DRUG: 13-15mg/kg/d Ursodeoxycholic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study With Immunotherapy With Dendritic Cells and Tumor Infiltrating Lymphocytes in Solid Tumors
Status: UNKNOWN
Conditions: Renal Cell Carcinoma|Melanoma|Carcinoma, Hepatocellular
Interventions: BIOLOGICAL: immunotherapy with dendritic cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucagon-like Peptide 1 Receptor Agonist in Acute Large Vessel Occlusion Stroke Treated by Reperfusion Therapies
Status: RECRUITING
Conditions: Stroke|Stroke, Acute|Stroke, Ischemic|Brain Diseases
Interventions: DRUG: Semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block For Lumbar Disc Hernia Repair
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Erector Spinae Plane block|PROCEDURE: Sham block|DRUG: Bupivacaine Hydrochloride|DEVICE: PCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cleanser Versus Only Water
Status: COMPLETED
Conditions: Premature Birth
Interventions: PROCEDURE: Bathing With Baby Cleanser and water|PROCEDURE: Bathing With only Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A 4-arm Clinical Trial of Fuse®, EndoCuff™, EndoRings™ and Standard Colonoscopy
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DEVICE: Colonoscopy with EndoCuff™|DEVICE: FUSE® Colonoscopy|DEVICE: Colonoscopy with EndoRings™|DEVICE: Standard Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Transhiatal/Transabdominal Approach Compare With Thoracoabdominal Approach for Siewert II Adenocarcinoma of Esophagogastric Junction
Status: RECRUITING
Conditions: Adenocarcinoma of Esophagogastric Junction
Interventions: PROCEDURE: transhiatal/transabdominal approach|PROCEDURE: thoracoabdominal approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Feasibility of Remote Monitoring of Mechanical In-exsufflation Devices in Paralytic and Neuromuscular Patients Treated at Home.
Status: RECRUITING
Conditions: Neuromuscular Diseases|Scoliosis
Interventions: DEVICE: MI-E Telemonitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multidimensional Predictive Modeling to Understand Mechanisms of Exercise Response Heterogeneity in Older Adults
Status: NOT_YET_RECRUITING
Conditions: Sarcopenia
Interventions: OTHER: Combined endurance and resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Electrical Muscle Stimulation and Bicycling Combined to Early Standard Rehabilitation in the ICU
Status: COMPLETED
Conditions: ICU-acquired Muscle Weakness
Interventions: OTHER: Early electrical stimulation and early leg bicycling added to early standard rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of BCD-100 (Anti-PD-1) in Combination With Platinum-Based Chemotherapy as First Line Treatment in Patients With Advanced Non-Squamous NSCLC
Status: UNKNOWN
Conditions: Non-Squamous Non-Small Cell Neoplasm of Lung
Interventions: BIOLOGICAL: BCD-100|DRUG: Pemetrexed|DRUG: Cisplatin (or carboplatin)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of GLP-1 Receptor Agonist on Cerebral Blood Flow Velocity in Non-stroke Volunteers
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Byetta|DRUG: Isotonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SP-420 in Subjects With Transfusion-dependent Beta-Thalassemia or Other Rare Anemias
Status: WITHDRAWN
Conditions: Iron Overload|Beta-Thalassemia
Interventions: DRUG: SP-420
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Staccato Loxapine in Agitated Patients With Schizophrenia
Status: COMPLETED
Conditions: Patients With Schizophrenia and Acute Agitation
Interventions: DRUG: Inhaled loxapine 5 mg|DRUG: Inhaled loxapine 10 mg|DRUG: Inhaled placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Effectiveness and Safety Study of Cyclobenzaprine HCl Alone or in Combination With Ibuprofen for Acute Back or Neck Muscle Pain With Muscle Spasm
Status: COMPLETED
Conditions: Pain|Spasm
Interventions: DRUG: cyclobenzaprine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing the Intensity of Priming Theta Burst Stimulation to Improve Hemiparetic Upper Limb Motor Functions After Stroke: a Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: DEVICE: Transcranial magnetic stimulation (TMS) - Theta burst stimulation (TBS) protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Registry Gangliosidoses
Status: RECRUITING
Conditions: Gangliosidoses|GM1 Gangliosidosis|Morquio B Disease|Sialidosis|Galactosialidosis|Gm2-Gangliosidosis, Variant B1|Tay-Sachs Disease|Sandhoff Disease|GM2 Activator Deficiency
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pancreatic Duct Stenting to Prevent Postoperative Pancreatic Fistula (POPF) After Distal Pancreatectomy
Status: SUSPENDED
Conditions: Pancreatitis
Interventions: DEVICE: Boston Scientific or Cook pancreatic duct stents
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Internal Radiation Therapy in Treating Patients With Low-Risk Prostate Cancer
Status: WITHDRAWN
Conditions: Adenocarcinoma of the Prostate|Recurrent Prostate Cancer|Stage I Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer
Interventions: RADIATION: brachytherapy|RADIATION: image-guided radiation therapy|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prompt Panretinal Photocoagulation Versus Ranibizumab+Deferred Panretinal Photocoagulation for Proliferative Diabetic Retinopathy
Status: COMPLETED
Conditions: Proliferative Diabetic Retinopathy
Interventions: OTHER: Prompt Panretinal Photocoagulation|DRUG: 0.5-mg Ranibizumab|OTHER: Deferred panretinal photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Ultrasound Elastography to Predict Development of Hepatic Sinusoidal Obstruction Syndrome
Status: RECRUITING
Conditions: Bone Marrow Transplant Complications|Sinusoidal Obstruction Syndrome|Veno Occlusive Disease, Hepatic|Stem Cell Transplant Complications
Interventions: DIAGNOSTIC_TEST: Ultrasound Elastography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Local Cecal Cancer - Optimization of Surgical Treatment
Status: RECRUITING
Conditions: Colonic Neoplasms Malignant|Cecal Neoplasms
Interventions: PROCEDURE: ileocecal resection with extended D3 lymphadenectomy.|PROCEDURE: Right hemicolectomy with D3 lymphadenectomy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pain and Anxiety in Peripheral Venous Catheterization, Jet Lidocaine, Ice Application
Status: COMPLETED
Conditions: Peripheral Venous Catheterization
Interventions: DRUG: Jet lidocaine|COMBINATION_PRODUCT: Ice|OTHER: Standard PVC procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Phase II Trial to Assess the Radiosensitizing Effect of ZARNESTRA in Patients With Glioblastoma Multiforme
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Zarnestra|PROCEDURE: standard Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Safety, Tolerability, and Immunogenicity of a Mosaic Hexavalent Influenza Vaccine VRC-FLUMOS0116-00-VP (FluMos-v2) in Healthy Adults
Status: RECRUITING
Conditions: Influenza
Interventions: BIOLOGICAL: VRC-FLUMOS0116-00-VP( FLUMos-v2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intratracheal Vitamin A Administration With Surfactant for Newborn Respiratory Distress Syndrome
Status: UNKNOWN
Conditions: RDS|Infant, Newborn|Vitamin A|Surfactant
Interventions: DRUG: surfactant|DRUG: surfactant+vitamin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring the Long-term Effects of Cognitive Exercise on Cognition After Stroke
Status: TERMINATED
Conditions: Chronic Phase Stroke Patients
Interventions: BEHAVIORAL: Variable Structured Cognitive Exercise|BEHAVIORAL: Constant Structured Cognitive Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telmisartan in Mild to Moderate Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Low dose of telmisartan|DRUG: High dose of telmisartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bicarbonates Versus Saline for Contrast Induced Acute Kidney Injury Prevention in Intensive Care Unit
Status: COMPLETED
Conditions: Contrast Induced Acute Kidney Injury
Interventions: DRUG: bicarbonates|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Solo and Non-solo Approach for Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Cholecystectomy, Laparoscopic
Interventions: PROCEDURE: nonsolo LC|PROCEDURE: solo LC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Efficacy and Acceptability of Two Missed Period Pills Regimens
Status: NOT_YET_RECRUITING
Conditions: Pregnancy Early|Pregnancy Related
Interventions: DRUG: Levonorgestrel|DRUG: Mifepristone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Ph I 5-day Temozolomide + O6-BG in Treatment of Pts w Recurrent / Progressive GBM
Status: COMPLETED
Conditions: Glioblastoma|Gliosarcoma
Interventions: DRUG: Temodar and O6-Benzylguanine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyproheptadine as an Appetite Stimulant
Status: UNKNOWN
Conditions: Failure to Thrive
Interventions: DRUG: Cyproheptadine|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Polyunsaturated Fatty Acids in Child Nutrition
Status: COMPLETED
Conditions: Fatty Acid Status
Interventions: OTHER: Fatty acid composition of complementary food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate Mepolizumab in the Treatment of Eosinophilic Granulomatosis With Polyangiitis
Status: COMPLETED
Conditions: Churg-Strauss Syndrome
Interventions: BIOLOGICAL: Mepolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation and Root Resorption
Status: COMPLETED
Conditions: Orthodontic Pathological Resorption of External Root|Orthodontic Appliance Complication|Orthodontic Tooth Movement
Interventions: DEVICE: Laser|DEVICE: light-emitting diode (LED)|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Prebiotics on Blood Glucose Management
Status: ACTIVE_NOT_RECRUITING
Conditions: Hyperglycemia|Insulin Sensitivity
Interventions: DIETARY_SUPPLEMENT: Highland barley β-glucan dietary supplement|OTHER: Placebo controls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of a Probiotic Strain on Aspirin-induced GI Damage.
Status: COMPLETED
Conditions: Side Effects of Acetylsalicylic Acid Use
Interventions: DIETARY_SUPPLEMENT: probiotic strain|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Promotion of Coronary Collateral Function by Ivabradine-Induced Bradycardia in Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Ivabradine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PACOME (PAtient Cancer Oral MEdication) Cohort of Patients Treated With Oral Anticancer Drugs Benefiting From Oncoral Multidisciplinary Monitoring in Real Life: Predictive Factors and Safety of Treatments
Status: NOT_YET_RECRUITING
Conditions: Cancer|Oncology|Oncoral Program
Interventions: OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Abuse Liability and Human Pharmacology of Mephedrone
Status: COMPLETED
Conditions: Amphetamine-Related Disorders
Interventions: DRUG: Mephedrone|DRUG: 3,4-methylenedioxymethamphetamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Efficacy and Safety of Liraglutide Versus Placebo as add-on to Existing Diabetes Medication in Subjects With Type 2 Diabetes and Moderate Renal Impairment
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pragmatic RCT Comparing Aripiprazole, Olanzapine and Haloperidol in the Treatment of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole|DRUG: Olanzapine|DRUG: Haloperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison the Postoperative Quality of Recovery Between Neostigmine and Sugammadex in Elderly Patients Undergoing Trans Pars Plana Vitrectomy With General Anesthesia -Randomized Controlled Trial-
Status: COMPLETED
Conditions: Elderly Patients Undergoing Trans Pars Plana Vitrectomy With General Anesthesia
Interventions: DRUG: Sugammadex|DRUG: Neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Breast Cancer Diet Intervention Study
Status: COMPLETED
Conditions: Early-stage Breast Cancer|Carbohydrate Engorgement|Proliferation|Insulin Resistance|Estrogen Receptor-positive Breast Cancer
Interventions: DIETARY_SUPPLEMENT: PreOP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparative Effectiveness Study Evaluating OROS Methylphenidate HCl, Ritalin (Methylphenidate HCl), and Placebo for the Treatment of Attention Deficit Hyperactivity Disorder in Children
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Ritalin|DRUG: OROS Methylphenidate HCl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Determination of Fibrin Activity in Plasma on STA-R® Prototype
Status: COMPLETED
Conditions: Blood Coagulation Disorders|Thrombotic Disorders|Hemorrhagic Disorders|Trauma
Interventions: OTHER: Routine hemostasis tests|OTHER: Fibrin structure (FS)|OTHER: Thromboelastography (TEG)|OTHER: Specialized hemostasis tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Value of Perianal Infiltration During Thermodestruction of Haemorrhoidal Disease by Radiofrequency
Status: RECRUITING
Conditions: Hemorrhoids
Interventions: DRUG: Ropivacaine|OTHER: Failure to perform peri-anal ropivacaine infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Results of Bronchoalveolar Lavage Culture and Endotracheal Aspirate Culture in Intubated Critically Ill COVID-19 Patients
Status: COMPLETED
Conditions: Bronchoalveolar Lavage|COVID-19 Pneumonia|Critical Illness
Interventions: PROCEDURE: Bronchoalveolar lavage|PROCEDURE: endotracheal aspirate culture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Second Line ColoRectal Cancer Therapy in Combination With Combination of FOL- Folinic Acid(Leucovorin), F - Fluorouracil and OX - Oxaliplatin (FOLFOX)
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: AZD2171|DRUG: 5-fluorouracil|DRUG: Leucovorin|DRUG: Oxaliplatin|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Total Contact Soft Cast in Diabetic Foot Ulcers
Status: RECRUITING
Conditions: Diabetic Foot Ulcer|Diabetes Mellitus|Foot Ulcer|Foot Ulcer, Diabetic|Ulcer|Ulcer Foot|Ulcer, Leg|Ankle Ulcer
Interventions: DEVICE: Total Contact Soft Cast|DEVICE: Cam Boot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcutaneous Electrical Nerve Stimulation (TENS) to Improve the Cognitive Functions in Older Adults
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: T1 TENS|DEVICE: Concha TENS|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Safety of Sativex Oromucosal Spray (Sativex®; Nabiximols) as Adjunctive Therapy in Patients With Uncontrolled Persistent Chronic Cancer Related Pain
Status: COMPLETED
Conditions: Pain|Advanced Cancer
Interventions: DRUG: Nabiximols
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing GSK2118436 to Dacarbazine (DTIC) in Previously Untreated Subjects With BRAF Mutation Positive Advanced (Stage III) or Metastatic (Stage IV) Melanoma
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: GSK2118436|DRUG: Dacarbazine (DTIC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Cannabidiol as a Novel Anticraving Medication for Alcohol Use Disorder
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: Oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Treatment With CO2 Laser and Isotretinoin for Acne Scars
Status: UNKNOWN
Conditions: Acne Vulgaris
Interventions: COMBINATION_PRODUCT: Isotretinoin and CO2 laser|DEVICE: Co2 laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Tolerability and Safety of RKI983 (0.05% & 0.10%) vs Xalatan in Patients With POAG or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: RKI983A|DRUG: RKI983A|DRUG: Latanoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Brain Mechanism of cTBS in Improving Medication-resistant Auditory Hallucinations in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Antipsychotic drugs|DEVICE: cTBS（the left temporoparietal cortex as the stimulation target）|DEVICE: cTBS （the left cerebellum Crus II as the stimulation target）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT