pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Low Frequency Electrical Stimulation of the Fornix in Intractable Mesial Temporal Lobe Epilepsy (MTLE)
Status: COMPLETED
Conditions: Mesial Temporal Lobe Epilepsy
Interventions: DEVICE: Medtronic Deep Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Sequential Oral Sensory Approach for Limited Food Repertoire in Children With Autism Spectrum Disorder
Status: UNKNOWN
Conditions: Autism Spectrum Disorder|Feeding Disorder|Restricted Diet
Interventions: BEHAVIORAL: SOS|OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen Therapy for Post Traumatic Stress Disorder
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: DEVICE: hyperbaric oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CTLA-4 and PD-1 Antibodies Expressing MUC1-CAR-T Cells for MUC1 Positive Advanced Solid Tumor
Status: UNKNOWN
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: Anti-CTLA-4/PD-1 expressing MUC1-CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Novel Technique of Mechanical Ventilation in Patients With Severe Acute Respiratory Failure
Status: COMPLETED
Conditions: Respiratory Distress Syndrome
Interventions: OTHER: High-frequency Oscillation and Tracheal Gas Insufflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Miniscrew Stability and Peri-implant Inflammation When Precoated K21 vs Ethanol Control
Status: RECRUITING
Conditions: Inflammation Caused by the Placement of a Temporary Anchorage Device
Interventions: DEVICE: K21 Cavity cleanser|DEVICE: Ethanol control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Tendon Vibration and Mirror for the Improvement of Upper Limb Function and Pain Reduction
Status: UNKNOWN
Conditions: Stroke|Hemiplegia
Interventions: DEVICE: Vibration and Mirror|DEVICE: Mirror therapy|DEVICE: no mirror, sham vibration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Assess Bioequivalence Between Nicorette Extra Mint Gum and Nicorette® Mint Gum in Healthy Smokers
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: DRUG: Nicorette Extra Mint 2 mg Gum|DRUG: Nicorette Mint 2 mg Gum|DRUG: Nicorette Extra Mint 4mg Gum|DRUG: Nicorette Mint 4 mg Gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Acupuncture in Chemotherapy-induced Nausea and Vomiting
Status: UNKNOWN
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: OTHER: Verum acupuncture and medicine|OTHER: Sham acupuncture and medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dill in Thyroiditis and Nodular Goiter Patients
Status: COMPLETED
Conditions: Thyroid Nodule
Interventions: DIETARY_SUPPLEMENT: Giving dill by mouth capsule to the study group and placebo capsule by mouth to the control group.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Protection of Ovarian Function in Female Patients With Hodgkin Lymphoma
Status: COMPLETED
Conditions: Hodgkins Lymphoma
Interventions: DRUG: 8 cycles BEACOPPesc plus oral contraceptive|DRUG: 8 cycles BEACOPPesc plus Goserelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VIVO Clinical Study
Status: COMPLETED
Conditions: Symptomatic Venous Outflow Obstruction in the Iliofemoral Vein
Interventions: DEVICE: Zilver Vena Venous Self-Expanding Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Feeding vs 5-day Fasting After Distal Elective Bowel Anastomoses in Children. A Randomized Controlled Trial
Status: COMPLETED
Conditions: Early Feeding|Bowel Anastomosis
Interventions: OTHER: Early feeding|OTHER: 5 day fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Abdominal or Transanal TME for Rectal Cancer Therapy
Status: RECRUITING
Conditions: Survival|Postoperative Morbidity|Mortality|Recurrence
Interventions: PROCEDURE: taTME|PROCEDURE: abdTME
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Lateral Window Technique Augmentation for Maxillary Sinus Using Ultrasound Activated Pins
Status: UNKNOWN
Conditions: Tooth Loss
Interventions: PROCEDURE: Lateral Window Technique Augmentation for Maxillary Sinus|DEVICE: Ultrasound activated resorbable poly-D-L-lactide pins|DEVICE: Purus® Cancellous Allograft|DEVICE: Resorb X Membrane|DEVICE: Biomend|PROCEDURE: Cone Beam CT image of the Sinus|PROCEDURE: Trephine Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double Blind, Randomized Trial of Bosentan for Sarcoidosis Associated Pulmonary Hypertension
Status: COMPLETED
Conditions: Sarcoidosis|Pulmonary Arterial Hypertension
Interventions: DRUG: Bosentan|DRUG: Placebo|DRUG: Bosentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intense Education of Periodontal Health Maintenance
Status: COMPLETED
Conditions: Chronical Periodontitis, Ratio of P. Gingivalis and S. Cristatus
Interventions: BEHAVIORAL: Intense education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I/II Study of Vaccination With Antigen Loaded Dendritic Cells (DCs) in Hormone-Refractory Prostate Cancer
Status: COMPLETED
Conditions: Cancer of the Prostate
Interventions: BIOLOGICAL: Dendritic cell application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Gemcitabine Versus S-1 Adjuvant Therapy After Hemihepatectomy for Biliary Tract Cancer
Status: COMPLETED
Conditions: Biliary Tract Cancer
Interventions: DRUG: Gemcitabine|DRUG: S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plasma Citrulline: A Marker for Monitoring & Quantifying Radiation-Induced Small Bowel Toxicity
Status: COMPLETED
Conditions: Diarrhea|Anorexia|Dyspepsia
Interventions: BIOLOGICAL: Plasma citrulline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Aerosols in the Treatment of Asymptomatic Pneumocystis Pneumonia: A Pilot Study Assessing the Effectiveness of Aerosolized Pentamidine as Treatment of Subclinical Pneumocystis Infection in Patients With No Clinical Symptoms
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Pentamidine isethionate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SWAP-MEAT With Athletes for MC-URC: Three Diets on Athletic Performance
Status: COMPLETED
Conditions: Health Behavior
Interventions: BEHAVIORAL: Diet order: PBMA, Animal|BEHAVIORAL: Diet order: Animal, PBMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Role of Ureteral Stenting Following Uncomplicated Ureteroscopy for Ureteral and Renal Stones: A Randomized, Controlled Trial
Status: COMPLETED
Conditions: Ureteroscopy
Interventions: DEVICE: Placement of ureteral stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab +/- Vaccine Therapy in Treating Patients With Locally Advanced, Unresectable or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Ipilimumab|BIOLOGICAL: Pancreatic Cancer Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INC280 and Erlotinib Hydrochloride in Treating Patients With Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-small Cell Lung Cancer
Interventions: DRUG: INC280|DRUG: erlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CYP1A2 and ADORA2A Genotypes and Endurance Performance.
Status: RECRUITING
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Caffeine 2 mg|DIETARY_SUPPLEMENT: Caffeine 4 mg|DIETARY_SUPPLEMENT: Caffeine 0 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: EUS RFA for Treatment of Pancreatic Ductal Adenocarcinoma (PDAC)
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: Chemotherapy|DEVICE: Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study Comparing Camoquin® Suspension (Pfizer) To Flavoquine® Tablets (Sanofi Aventis) In Healthy Subjects
Status: COMPLETED
Conditions: Falciparum Malaria
Interventions: DRUG: Flavoquine®, Camoquin® Suspension|DRUG: Flavoquine®, Camoquin® Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Versus Transvaginal Approaches in Repair of Uterine Niche: A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Uterine Niche
Interventions: PROCEDURE: Laparoscopic repair of Uterine niche|PROCEDURE: Transvaginal repair of Uterine niche
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: FOLFOX vs Gemcitabine in Patients With Metastatic Pancreatic Cancer Non-fit to FOLFIRINOX
Status: RECRUITING
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Gemcitabine|DRUG: FOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Apneic Oxygenation During Prolonged Intubation in Pediatric Patients: a Randomized Clinical Trial
Status: COMPLETED
Conditions: Intubation of Pediatric Dental Surgery Patients
Interventions: DEVICE: TrueView PCD Video Laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Axillary Node Dissection w or w/o LVB in Node Positive Breast Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Node-positive Breast Cancer
Interventions: PROCEDURE: Axillary Lymph Node Dissection|PROCEDURE: Axillary Reverse Mapping|PROCEDURE: Lymphaticovenous Bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Traditional Versus Computerized Mandibular Reconstruction
Status: WITHDRAWN
Conditions: Free Tissue Transfer|Mandible Reconstruction|Computerized Customization
Interventions: PROCEDURE: Customized Jigs and Plates|PROCEDURE: Hand Contoured Osteotomies and Reconstruction Bars
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intrauterine Injection of Hcg Before ET on Clinical Outcomes in IVF/ICSI Cycles
Status: COMPLETED
Conditions: Infertility|ART
Interventions: DRUG: Human Chorionic Gonadotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Use of Indocyanine Green and 99mTc-labeled Radiotracer for Axillary Lymphatic Mapping in Patients With Breast Cancer
Status: COMPLETED
Conditions: Stage I Breast Cancer|Stage II Breast Cancer
Interventions: DRUG: Indocyanine Green Solution|RADIATION: Technetium Tc-99m Sulfur Colloid|PROCEDURE: Lymphoscintigraphy|PROCEDURE: Axillary Lymph Node Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Diagnostic Potential of Artificial Intelligence-assisted Fecal Microbiome Testing for Inflammatory Bowel Disease
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases|Microbiota|Colonoscopy
Interventions: DIAGNOSTIC_TEST: Artificial Intelligence-assisted Fecal Microbiome Testing|PROCEDURE: Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Equivalency Validation Protocol Clinical Equivalency Eyenez Retina Camera v200 and Optomed Smartscope M5 EY3
Status: COMPLETED
Conditions: Diabetes
Interventions: DEVICE: Eyenez Retinal Camera v200|DEVICE: Volk Pictor Ret 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Phase 2 DaxibotulinumtoxinA for Injection for the Management of Plantar Fasciitis
Status: COMPLETED
Conditions: Plantar Fasciitis
Interventions: BIOLOGICAL: Botulinum Toxins, Type A|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Euclid Phoenix Lens Design Trial 2
Status: NOT_YET_RECRUITING
Conditions: Myopia|Cornea
Interventions: DEVICE: Euclid orthokeratology (standard coating)|DEVICE: Euclid orthokeratology (enhanced coating)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of ISX (Isoxsuprine HCL) in MS Relapses
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Isoxsuprine Hydrochloride|DRUG: Placebo|DRUG: Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rapamune Improves Outcomes of Severe H1N1 Pneumonia
Status: COMPLETED
Conditions: H1N1 Pneumonia|Hypoxemia
Interventions: DRUG: Sirolimus (Rapamune 2mg/day, Pfizer)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of PD-0332991 in Advanced Gastrointestinal Stromal Tumors Refractory to Imatinib and Sunitinib
Status: COMPLETED
Conditions: Advanced Gastrointestinal Stromal Tumors
Interventions: DRUG: PD 0332991
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of 7-valent Pneumococcal Conjugate Vaccine in Children With Idiopathic Nephrotic Syndrome
Status: UNKNOWN
Conditions: Idiopathic Nephrotic Syndrome
Interventions: BIOLOGICAL: 7-valent pneumococcal conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bone Reconstruction of the Skull Using a Metal Ceramic Implant After Previously Failed Reconstruction
Status: UNKNOWN
Conditions: Defect of Skull Ossification|Other Specified Skull or Face Bone Anomaly|Cranial Dysostosis Nec|Hemicraniectomy
Interventions: DEVICE: OssDsign AB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analyzing the Pharmacodynamic Substances and the Effects of Xingnaojing for Mild-to-Severe Acute Ischemic Stroke
Status: UNKNOWN
Conditions: Ischemic Stroke, Acute
Interventions: DRUG: Xingnaojing injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of a Probiotic on the Female Genital Tract Microbiota of Participants With Fertility Disorders.
Status: RECRUITING
Conditions: Fertility Disorders
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Ashwagandha in Endurance Exercise Performance
Status: UNKNOWN
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Ashwagandha extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Apnea Tolerance in Bariatric Patients Following Rapid-sequence Induction of Anesthesia
Status: COMPLETED
Conditions: General Surgery
Interventions: OTHER: 25° head-up position|OTHER: 55° head-up position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Pharmacokinetics of P1101 + Ribavirin in Interferon Treatment-Naïve Subjects With Chronic Hepatitis C Virus (HCV) Genotype 2 Infection
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: P1101 + Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: KN026 Plus Chemotherapy ± KN-046 in HER2 Positive Colorectal Cancer and Biliary Carcinoma
Status: NOT_YET_RECRUITING
Conditions: HER2-positive Colorectal Cancer|HER2-positive Biliary Tract Cancer
Interventions: DRUG: KN026|DRUG: KN046|DRUG: XELOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Mindfulness-Based Health Promotion Program (MBHP) in the Elderly: a RCT
Status: UNKNOWN
Conditions: Quality of Life|Cognitive Impairment|Psychological
Interventions: OTHER: Mindfulness-Based Intervention|OTHER: Cognitive Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An In Silico Trial to Evaluate Prospectively the Performance of a Radiomics Algorithm for UIP Compared to Medical Doctors
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis|Interstitial Lung Disease|Radiomics
Interventions: OTHER: Radiomics model to classify between IPF with UIP pattern and ILDs without UIP pattern
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumors
Status: COMPLETED
Conditions: Breast Cancer|Chronic Myeloproliferative Disorders|Gestational Trophoblastic Tumor|Kidney Cancer|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Neuroblastoma|Ovarian Cancer|Testicular Germ Cell Tumor
Interventions: BIOLOGICAL: recombinant interleukin-12
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Adjunctive Nitrous Oxide During Emergency Department Propofol Sedation in Adults
Status: COMPLETED
Conditions: Joint Dislocation|Perianal Abscess|Abscess
Interventions: DRUG: Nitrous Oxide arm|DRUG: Propofol|DRUG: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BP101 for Adults With Female Sexual Dysfunction
Status: COMPLETED
Conditions: Hypoactive Sexual Desire Disorder|Female Sexual Dysfunction|Sexual Desire Disorder
Interventions: DRUG: BP101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protein Quality on Appetite Control, Reward-driven Eating, & Subsequent Food Intake
Status: COMPLETED
Conditions: Appetite and General Nutritional Disorders
Interventions: OTHER: Macronutrient and Fiber Matched BEEF|OTHER: Macronutrient and Fiber Matched SOY|OTHER: Serving Size Matched BEEF|OTHER: Serving Size Matched SOY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
Status: RECRUITING
Conditions: Community-acquired Pneumonia, Influenza, COVID-19
Interventions: DRUG: Ceftriaxone|DRUG: Moxifloxacin or Levofloxacin|DRUG: Piperacillin-tazobactam|DRUG: Ceftaroline|DRUG: Amoxicillin-clavulanate|DRUG: Standard course macrolide|DRUG: Extended course macrolide|OTHER: No systemic corticosteroid|DRUG: Fixed-duration Hydrocortisone|DRUG: Shock-dependent hydrocortisone|DRUG: Fixed-duration higher dose Hydrocortisone|OTHER: No antiviral agent for influenza|DRUG: Five-days oseltamivir|DRUG: Ten-days oseltamivir|OTHER: No antiviral agent for COVID-19|DRUG: Lopinavir / Ritonavir|DRUG: Hydroxychloroquine|DRUG: Hydroxychloroquine + lopinavir/ritonavir|DRUG: Ivermectin|OTHER: No immune modulation for COVID-19|DRUG: Interferon beta-1a|DRUG: Anakinra|DRUG: Tocilizumab|DRUG: Sarilumab|DRUG: Local standard venous thromboprophylaxis|DRUG: Therapeutic dose anticoagulation|DRUG: Conventional low dose thromboprophylaxis|DRUG: Intermediate dose thromboprophylaxis|DRUG: Continuation of therapeutic dose anticoagulation|OTHER: No immunoglobulin|BIOLOGICAL: Convalescent plasma|BIOLOGICAL: Delayed administration of convalescent plasma|OTHER: No vitamin C|DRUG: Vitamin C|OTHER: No antiplatelet|DRUG: Aspirin|DRUG: P2Y12 inhibitor|OTHER: No simvastatin|DRUG: Simvastatin|DRUG: Eritoran|DRUG: Apremilast|PROCEDURE: Clinician-preferred mechanical ventilation strategy|PROCEDURE: Protocolised mechanical ventilation strategy|OTHER: No renin-angiotensin system inhibitor|DRUG: Angiotensin converting enzyme inhibitor|DRUG: Angiotensin Receptor Blockers|DRUG: ARB + DMX-200|OTHER: No cysteamine|DRUG: Cysteamine|DRUG: Fixed-duration dexamethasone|DRUG: Baloxavir Marboxil|DRUG: Five-days oseltamivir + baloxavir marboxil|DRUG: Ten-days oseltamivir + baloxavir marboxil|OTHER: No endothelial modulator|DRUG: Imatinib|OTHER: No Immune Modulator for Influenza|DRUG: Tocilizumab|DRUG: Baricitinib|OTHER: No antiviral agent for COVID-19|DRUG: Nirmatrelvir/ritonavir|DRUG: Remdesivir|DRUG: Nirmatrelvir/ritonavir + remdesivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Carbohydrate Source on Food Intake, Blood Glucose and Gut Hormone Response in Healthy Children
Status: COMPLETED
Conditions: Obesity|Diabetes
Interventions: DIETARY_SUPPLEMENT: Rice treatment|DIETARY_SUPPLEMENT: Pasta treatment|DIETARY_SUPPLEMENT: Boiled and mashed potato treatment|DIETARY_SUPPLEMENT: Baked french fries treatment|DIETARY_SUPPLEMENT: Fried french fries treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial on Impact of HealthPROMISE Mobile App on Inflammatory Bowel Disease Care and Quality of Life
Status: COMPLETED
Conditions: Inflammatory Bowel Disease|Crohn's Disease|Ulcerative Colitis
Interventions: OTHER: HealthPROMISE users|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Iranian Traditional Medicine Remedy on Chemotherapy Induced Nausea and Vomiting
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: DRUG: Persumac|DRUG: lactose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transumbilical Versus Transvaginal Specimen Retrieval at Minilaparoscopy
Status: COMPLETED
Conditions: Postoperative Pain|Patients Satisfaction|Intraoperative Complications|Postoperative Complications
Interventions: PROCEDURE: TRANSVAGINAL SPECIMEN EXTRACTION|PROCEDURE: TRANSUMBILICAL SPECIMEN EXTRACTION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Percussive Therapy Reduced EMG Activity During Calf Raise in Limbs With and Without Chronic Ankle Instability
Status: COMPLETED
Conditions: Ankle Injuries
Interventions: DEVICE: Percussive massage gun therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Endoscopic Resection of Papillary Adenomas; a Novel Treatment Algorithm to Prevent Recurrence - a Pilot-study (ERASE-pilot)
Status: RECRUITING
Conditions: Papillary Adenoma
Interventions: OTHER: Thermal ablation of resection margins by STSC and biliary orifice by cystotome.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Response of Impulsivity After Brain Stimulation in Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Impulsive Behavior|Impulse Disorders|Gambling, Pathological|Eating, Binge|Hoarding Disorder|Hypersexuality|Compulsive Shopping|Dopamine Dysregulation Syndrome|Caregiver Burnout|Parkinson Disease
Interventions: DEVICE: Subthalamic Nucleaus Deep brain stimulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Post-Transplant Cyclophosphamide in Patients Aged >/= 65 Years Undergoing Haploidentical Transplant
Status: RECRUITING
Conditions: Hematologic Malignancies
Interventions: DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Doses of SY-009 in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: SY-009|DRUG: SY-009 matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraarticular Injections of Platelet-rich Plasma in Pain's Treatment of the Osteoarthritic Knee
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Platelet rich plasma|DRUG: Hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Stinging Potential in Human Eyes
Status: COMPLETED
Conditions: Sunscreen Agents
Interventions: DRUG: BAY 987516 (Y65-122)|DRUG: BAY 987516 (Y65-118)|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Complex Abdominal, TAAA, Aortic Arch Aneurysm or Dissections With Fenestrated/Branched Stent Graft
Status: RECRUITING
Conditions: Complex Abdominal Aortic Aneurysm|Thoracoabdominal Aortic Aneurysm|Aortic Arch Aneurysm|Aortic Arch Dissection
Interventions: DEVICE: Thoracoabdominal Aortic Aneurysm Arm|DEVICE: Aortic Arch Aneurysm Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Kendall Exercise VS Gong's Mobilization on Pain, Range of Motion, Function, and Strength in Cases With UCS
Status: ACTIVE_NOT_RECRUITING
Conditions: Syndrome, Down
Interventions: COMBINATION_PRODUCT: Gong's mobilization|OTHER: Kendall Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV)
Status: NOT_YET_RECRUITING
Conditions: Tricuspid Regurgitation|Tricuspid Valve Disease
Interventions: DEVICE: TricValve® Transcatheter Bicaval Valve System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fatty Acid Oxidation Defects and Insulin Sensitivity
Status: COMPLETED
Conditions: Very Long-chain Acyl-CoA Dehydrogenase Deficiency|Trifunctional Protein Deficiency|Long-chain 3-hydroxyacyl-CoA Dehydrogenase Deficiency|Medium-chain Acyl-CoA Dehydrogenase Deficiency|Normal Volunteers|Carnitine Palmitoyltransferase II Deficiency, Myopathic
Interventions: DRUG: Intralipid/Heparin|DRUG: Glycerol/Saline|DRUG: Hyperinsulinemic euglycemic clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Indonesia After Discharge LBW Infant HMF Supplementation Study
Status: COMPLETED
Conditions: Low; Birthweight|Breast Feeding, Exclusive|Gestational Age and Weight Conditions
Interventions: DIETARY_SUPPLEMENT: human milk fortified|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Paclitaxel in Treating Patients With Locally Advanced or Metastatic Soft Tissue Angiosarcoma or Lymphangiosarcoma That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimally-invasive Non-surgical and Surgical Periodontitis Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Periodontitis
Interventions: PROCEDURE: MINST|PROCEDURE: MIST|DIAGNOSTIC_TEST: GTI subgroup (Geometrical/Thermal Imaging)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Complete Local Response to Neoadjuvant Chemotherapy in Patients With Muscle Invasive Bladder Cancer Evaluated by 15O-H2O PET/MR
Status: UNKNOWN
Conditions: Bladder Cancer
Interventions: RADIATION: 15O-H2O PET/MR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dutasteride Versus Placebo and Finasteride in Men With Androgenetic Alopecia
Status: COMPLETED
Conditions: Androgenetic Alopecia
Interventions: DRUG: 1mg Finasteride active|DRUG: 0.02mg dutasteride|DRUG: 0.1mg dutasteride|DRUG: 0.5mg dutasteride|DRUG: Finasteride placebo|DRUG: Dutasteride placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Trial of 2-Deoxy-D-Glucose (2DG) in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Lung Cancer|Breast Cancer|Pancreatic Cancer|Head and Neck Cancer|Gastric Cancer
Interventions: DRUG: 2-deoxy-D-glucose (2DG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Postoperative Anti-nausea and Vomiting Effect Between Glycopyrronium and Ondansetron
Status: UNKNOWN
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Glycopyrronium|DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Relative Oral Bioavailability of a Single Dose of JNJ-53718678 Administered as Oral Concept Formulation Compared to the Current Oral Solution and to Assess the Effect of Food on the Pharmacokinetics of Oral Concept Formulation
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-53718678
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vasopressors for Cerebral Oxygenation
Status: UNKNOWN
Conditions: Hypoxia|Hypotension
Interventions: DRUG: dopamine|DRUG: phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compensatory Cognitive Training in Clinical High Risk Latino Youth
Status: UNKNOWN
Conditions: Clinical High Risk|Psychosis|Prodromal|Schizophrenia
Interventions: BEHAVIORAL: Compensatory Cognitive Training|BEHAVIORAL: Recreational Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study of Ibrutinib (PCI-32765) Versus Ofatumumab in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Relapsed or Refractory Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: ofatumumab|DRUG: ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Chronic Post-Partum Pelvic Girdle Pain Study
Status: COMPLETED
Conditions: Pelvic Girdle Pain|Symphysis Pubis Dysfunction
Interventions: DEVICE: Customised Dynamic Elastomeric Fabric Orthosis (DEFO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ginkgolide on Clinical Improvement of Patients With Acute Ischemic Stroke
Status: RECRUITING
Conditions: Ischemic Stroke, Acute
Interventions: DRUG: Ginkgo diterpene lactone meglumine injection|DRUG: Ginkgo diterpene lactone meglumine injection simulation|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Therapy on Mitochondrial Functions of Lymphocyte in Hemodialysis
Status: RECRUITING
Conditions: Hemodialysis Complication
Interventions: BEHAVIORAL: Supervised exercise training|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Mesenchymal Stem Cell and Exosome in Treating Pilonidal Sinus Disease in Children
Status: RECRUITING
Conditions: Pilonidal Sinus|Pilonidal Disease
Interventions: OTHER: Crystallized phenol|BIOLOGICAL: Crystallized phenol + Exosome|BIOLOGICAL: Crystallized phenol + Stem Cell|BIOLOGICAL: Crystallized phenol + Exosome + Stem Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Primovist-enhanced MRI, Diffusion Weighted MRI and Multidetector CT of Colorectal Liver Metastases
Status: COMPLETED
Conditions: Colorectal Liver Metastases
Interventions: OTHER: MR imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Terbinafine Film Forming Solution in Patients With Tinea Pedis
Status: COMPLETED
Conditions: Tinea Pedis
Interventions: DRUG: Terbinafine|DRUG: Terbinafine Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Benefits of Using Laryngeal Mask Airway to Keep Airway Potency During Fiber-optic Bronchoscopy
Status: COMPLETED
Conditions: Respiratory Disease Undergoing Elective Bronchoscopy.|Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Laryngeal Mask Airway (LMA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Medical and Economic Evaluation of a Magnetic Anal Sphincter for Patients With Severe Anal Incontinence
Status: SUSPENDED
Conditions: Fecal Incontinence|Anal Incontinence
Interventions: DEVICE: magnetic anal sphincter|DEVICE: sacral nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ProQuad™ Versus M-M-R II™ and VARIVAX™ in Healthy Children (V221-009)(COMPLETED)
Status: COMPLETED
Conditions: Measles|Mumps|Rubella|Varicella
Interventions: BIOLOGICAL: Measles, Mumps, Rubella and Varicella (Oka-Merck) Virus Vaccine Live|BIOLOGICAL: Comparator: Placebo|BIOLOGICAL: Comparator: Varivax|BIOLOGICAL: Comparator: M-M-R II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Acupuncture in the Management of Postoperative Pain in the Pediatric Intensive Care Unit
Status: NOT_YET_RECRUITING
Conditions: Pain, Postoperative|Pediatric Disorder
Interventions: DEVICE: Sham press needle|DEVICE: Press needle acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Uniportal Tubeless VATS for the Evaluation of Biopsy for Second-generation Sequencing in Patients With Advanced NSCLC
Status: UNKNOWN
Conditions: NSCLC|Biopsy Technique|VATS|CT Guided Puncture Biopsy|NGS
Interventions: DIAGNOSTIC_TEST: vats|DIAGNOSTIC_TEST: CT-guided fine needle biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial of De-Intensified Post-operative Chemoradiation Following Robotic Surgery for HPV-positive Oropharyngeal Cancer
Status: RECRUITING
Conditions: HPV Positive Oropharyngeal Squamous Cell Carcinoma
Interventions: RADIATION: Cisplatin-based Radiation Therapy|DRUG: Cisplatin Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Droxidopa for Fatigue in Patients With Parkinsonism
Status: WITHDRAWN
Conditions: Parkinson Disease|Multiple System Atrophy|Progressive Supranuclear Palsy
Interventions: DRUG: Droxidopa|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Navelbine and Capecitabine in the Treatment of Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Navelbine|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Therapy Integrated With Mindfulness for Patients With Chronic Pain and Opioid Treatment
Status: RECRUITING
Conditions: Chronic Pain|Pain, Musculoskeletal|Opioid Use|Physical Therapy
Interventions: BEHAVIORAL: Mindfulness based practice|BEHAVIORAL: Control/Standard Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Immunogenicity of Three Formulations of Vi-CRM197 Vaccine Against S. Typhi in Adults (18-40 Years Old)
Status: COMPLETED
Conditions: Typhoid Fever
Interventions: BIOLOGICAL: NVGH Vi-CRM197 12.5 mcg|BIOLOGICAL: NVGH Vi-CRM197 5.0 mcg|BIOLOGICAL: NVGH Vi-CRM197 1.25 mcg|BIOLOGICAL: Vi-polysaccharide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Directional Preference Exercises in Comparison to Motor Control Exercises in Mechanical Low Back Pain
Status: ENROLLING_BY_INVITATION
Conditions: Low Back Pain, Mechanical
Interventions: DEVICE: THE therapy|PROCEDURE: Directional Preference Exercises|PROCEDURE: Motor Control Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Regorafenib in Patients With Pretreated Advanced Melanoma
Status: RECRUITING
Conditions: Melanoma Stage III|Melanoma Stage IV
Interventions: DRUG: Regorafenib 40 MG Oral Tablet|DRUG: Triplet therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Determine the Safety and Efficacy of Gardasil Against the Human Papilloma Virus (HPV) in HIV-infected Men
Status: UNKNOWN
Conditions: Anal Cancer|HIV Infections
Interventions: BIOLOGICAL: Gardasil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Oro-cecal Transit Time in Healthy Subjects Using Scintigraphy and Lactulose Hydrogen Breath Test.
Status: UNKNOWN
Conditions: Small Bowel Disease|Motility Disorder|Irritable Bowel Syndrome
Interventions: DIAGNOSTIC_TEST: 99mTc Scintigraphy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Equivalence of Calcium Acetate Oral Solution and Sevelamer Carbonate Tablets in Hemodialysis Patients
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Calcium acetate oral solution (COS)|DRUG: Sevelamer carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cardiopulmonary Rehabilitation in Participants With Post-COVID 19 Syndrome.
Status: COMPLETED
Conditions: Post- COVID-19 Syndrome|Exercises|Pulmonary Rehabilitation|COVID-19|Randomized Clinical Trial
Interventions: OTHER: Pulmonary rehabilitation exercises at the Rehabilitation Center|OTHER: Home Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tiotropium and Salmeterol in Moderate Persistent Asthma Patients Homozygous for B16-Arg/Arg
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Tiotropium bromide|DRUG: Placebo|DRUG: Salmeterol xinafoate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Post-Operative Delirium in Elderly Surgical Patients
Status: COMPLETED
Conditions: Hip Fractures|Delirium
Interventions: DEVICE: Deeper sedation|DEVICE: Moderate sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Move With Air: Exercise Training Study
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease|Interstitial Lung Disease|Heart Failure
Interventions: DEVICE: Honeywell HT-900 Turbo Force Air Circulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of SAR440340 (Anti-IL-33 mAb) in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: SAR440340|DRUG: Placebo|DRUG: Any Inhaled Corticosteroids as prescribed by treating physician as standard of care|DRUG: Any Long Acting Beta Agonist as prescribed by treating physician as standard of care|DRUG: Any Long Acting Muscarinic Agonist as prescribed by treating physician as standard of care|DRUG: Any short-acting β agonist as prescribed by treating physician as standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Autologous Bone Marrow Aspirate Concentrate in Painful Knee Osteoarthritis
Status: COMPLETED
Conditions: Bilateral Primary Osteoarthritis of Knee
Interventions: DRUG: Autologous Bone Marrow Aspirate Concentrate|DRUG: Sterile saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Golidocitinib in Combination With Sintilimab for PD-L1 Selected Treatment Locally Advanced or Metastatic Non-Small Cell Lung Cancer(NSCLC)
Status: NOT_YET_RECRUITING
Conditions: Non-Small-Cell Lung Cancer
Interventions: DRUG: Golidocitinib|DRUG: Sintilimab|DRUG: platinum doublet chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Efficacy of ELA026 in Participants With Secondary Hemophagocytic Lymphohistiocytosis
Status: RECRUITING
Conditions: Secondary Hemophagocytic Lymphohistiocytosis (sHLH)
Interventions: DRUG: ELA026
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zurich Multiple Endpoint Vitamin D Trial in Knee OA Patients
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: Vitamin D3 (cholecalciferol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT