pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Online HOPE Intervention on Mental Health Literacy Among Youths in Singapore: An RCT Protocol
Status: UNKNOWN
Conditions: Mental Health Literacy|Depression Literacy|Psychological Well-being|Stress, Psychological
Interventions: BEHAVIORAL: Online HOPE intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Efficacy and Safety of Tilpisertib in Adults With Moderately to Severely Active Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: Tilpisertib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Low Calorie Diet Containing Nuts on Systemic and Vascular Inflammation
Status: COMPLETED
Conditions: Cardiovascular Risk Factor
Interventions: DIETARY_SUPPLEMENT: Nut consumption|OTHER: Low calorie diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chronomodulated Chemotherapy Followed by Concurrent Chemo-radiotherapy With IMRT in the Treatment of Advanced Nasopharyngeal Cancer
Status: UNKNOWN
Conditions: Esophageal Neoplasms
Interventions: DEVICE: Chrono-chemotherapy pump:Melodie|DEVICE: Routine intravenous drip|DRUG: induction Chrono-chemotherapy|DRUG: induction Routine-chemotherapy|DRUG: cisplatin chrono-chemotherapy|DRUG: cisplatin routine-chemotherapy|RADIATION: intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy of Ophthalmic Solution in Induced Acute Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: R89674 (generic name not yet established)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Patient Education Videos to Improve Patients' Experience During Radiotherapy Treatment: a National Project
Status: RECRUITING
Conditions: Cancer, Breast|Cancer, Lung|Cancer Prostate|Cancer Head Neck|Cancer, Gastrointestinal
Interventions: DEVICE: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Open-label Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
Status: ENROLLING_BY_INVITATION
Conditions: Major Depressive Disorder
Interventions: DRUG: Lumateperone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lateral Canthal Rhytides With Medium Depth Chemical Peel With or Without Pretreatment With Botulinum Toxin A
Status: COMPLETED
Conditions: Wrinkles
Interventions: DRUG: Botulinum Toxin|PROCEDURE: Chemical Peel Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial to Assess TroVax® Plus Chemotherapy in Patients With Malignant Pleural Mesothelioma
Status: UNKNOWN
Conditions: Malignant|Pleural|Mesothelioma
Interventions: BIOLOGICAL: TroVax®|DRUG: Pemetrexed|DRUG: Cisplatin|DIETARY_SUPPLEMENT: Vitamin B12|DIETARY_SUPPLEMENT: Folic Acid|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRX-I Versus Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infection
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: DRUG: MRX-I|DRUG: Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Multicentric Trial Between Radiofrequency Ablation With VNUS Closure Fast ® and Endovenous Ablation With 1470 nm Diode Laser and Tulip Fiber ® for Treatment of Primary Venous Insufficiency.
Status: COMPLETED
Conditions: Chronic Venous Insufficiency C2 or Higher
Interventions: DEVICE: Tulip fiber|DEVICE: VNUS closure fast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Trial of Z-338 in Paediatric Patients With Functional Dyspepsia
Status: RECRUITING
Conditions: Functional Dyspepsia
Interventions: DRUG: Acotiamide hydrochloride hydrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Benefits of Opioid Free Anesthesia on Morphine Consumption in Gastric Bypass
Status: COMPLETED
Conditions: Analgesics, Opioid
Interventions: DRUG: Dexmedetomidine Injection [Precedex]|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thigh Reduction Surgery of Above Knee Amputee Residual Limbs to Improve Prosthesis Fit and Patient Outcomes
Status: COMPLETED
Conditions: Transfemoral Amputees
Interventions: PROCEDURE: Medial thighplasty with or without thigh liposuction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Maintenance Capecitabine Plus Best Supportive Care Versus Best Supportive Care for Metastatic Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: capecitabine|OTHER: Best supportive care (BSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Methods for Intra- and Postoperative Pain Therapy in Thoracic Surgery
Status: RECRUITING
Conditions: Thoracic Surgery
Interventions: PROCEDURE: Regional anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thought Field Therapy and Cognitive Therapy for Agoraphobia
Status: COMPLETED
Conditions: Agoraphobia
Interventions: BEHAVIORAL: Thought field therapy|BEHAVIORAL: Cognitive therapy|BEHAVIORAL: Wait list
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pericapsular Nerve Group Block and Quadratus Lumborum Block
Status: COMPLETED
Conditions: Total Hip Surgery|Pericapsular Nerve|Quadratus Lumborum
Interventions: DRUG: PENG/LFCN and QL Blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Calcium Hydroxybenzene Sulphonate Dispersible Tablets in Chinese Healthy Volunteers
Status: RECRUITING
Conditions: Bioequivalence Study
Interventions: DRUG: Calcium Hydroxybenzene Sulphonate Dispersible Tablets 0.25g|DRUG: Calcium Hydroxybenzene Sulfonate Tablets（Doxium®) 250mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mycophenolate Mofetil in Antiretroviral Naïve Patients 2 (MAN2 Study)
Status: UNKNOWN
Conditions: HIV Infection
Interventions: DRUG: mycophenol mofetil (MMF, Cellcept®) 500 mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Develop the First Aid Medical Supplies for Hemostasis and Bacteriostasis With Clinical Trial
Status: UNKNOWN
Conditions: Cesarean Section
Interventions: DEVICE: Regular Gauze|DEVICE: Chitosan Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of GLP-1 on Glucose Metabolism in CNS Assessed by PET
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: native glp-1 (7-36)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combined Pharmacotherapy for Cannabis Dependency
Status: COMPLETED
Conditions: Cannabis Dependence|Marijuana Dependence
Interventions: DRUG: Dronabinol|DRUG: Placebo|DRUG: Lofexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Trial of Live Attenuated Influenza (H7N3) Vaccine
Status: COMPLETED
Conditions: Influenza|Avian Influenza
Interventions: BIOLOGICAL: LAIV H7N3|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 386 When Used in Combination With AMG 706, Bevacizumab, Sorafenib, or Sunitinib.
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: Sorafenib|DRUG: AMG 706|DRUG: AMG 706|DRUG: AMG 386|DRUG: Sunitinib|DRUG: Bevacizumab|DRUG: AMG 386
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-Center Study of Clinical and Inflammatory Outcomes in Intensive Cardiac Rehabilitation and Traditional Cardiac Rehabilitation Programs
Status: RECRUITING
Conditions: Cardiovascular Diseases
Interventions: BEHAVIORAL: Traditional Cardiac Rehabilitation|BEHAVIORAL: Intensive Cardiac Rehabilitation|OTHER: C2life® Food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Bioequivalence Study of Umifenovir 200 mg Capsul (ATABAY, Turkey) Under Fasting Conditions
Status: UNKNOWN
Conditions: Bioequivalence
Interventions: DRUG: ATAFENOVIR 200 MG KAPSUL|DRUG: ARBIDOL 100 MG KAPSUL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase 3 Study of Fluvoxamine (SME3110) in Pediatric/Adolescent Patients With Obsessive Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: DRUG: Fluvoxamine maleate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Allergic Rhinitis, Immunotherapy and Vitamin d
Status: UNKNOWN
Conditions: Allergy
Interventions: DRUG: Vitamin D3|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of EVEROLIMUS in Patients With Primary or Relapsed Chondrosarcomas
Status: SUSPENDED
Conditions: Chondrosarcoma
Interventions: DRUG: Everolimus 2.5 mg/day|DRUG: Everolimus 10 mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Safety of Lampalizumab Intravitreal (ITV) Injections in Participants With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (OMASPECT)
Status: TERMINATED
Conditions: Geographic Atrophy
Interventions: DRUG: Lampalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Amlodipine and Benazepril HCl Capsules 10 mg/20 mg to Lotrel® Capsules 10 mg/20 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Amlodipine and Benazepril HCl Capsules 10 mg/20 mg|DRUG: Lotrel® Capsules 10 mg/20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: AML Treatment in Untreated Adult Patients
Status: UNKNOWN
Conditions: Leukemia, Myelocytic, Acute
Interventions: PROCEDURE: Identification of appropriate therapies according to risks factors|DRUG: Daunorubicine|PROCEDURE: Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: the Fetal Epicardial Thickness in Obese Pregnant Women (EFT)
Status: COMPLETED
Conditions: Fetus Fetus|Pregnancy Complications
Interventions: DIAGNOSTIC_TEST: Doppler ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: The Efficacy of a Tart Cherry Drink for the Treatment of Patellofemoral Pain in Recreational Athletes.
Status: COMPLETED
Conditions: Patellofemoral Pain
Interventions: DIETARY_SUPPLEMENT: Cherry juice|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Clinical Effect, Pharmacokinetics , Safety, and Tolerability of Umeclidinium in Palmar Hyperhidrosis Subjects
Status: COMPLETED
Conditions: Hyperhidrosis
Interventions: DRUG: Umeclidinium|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nonopioid Analgesia After Rotator Cuff Repair
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: DRUG: Celecoxib|DRUG: Ketorolac|DRUG: Gabapentin|DRUG: Acetaminophen|DRUG: Diazepam|DRUG: Hydrocodone-Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Silk Road Medical First in Man Study - Neuroprotection During Carotid Stenting and Angioplasty
Status: COMPLETED
Conditions: Carotid Artery Diseases
Interventions: DEVICE: Silk Road Embolic Protection System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Follow-up Study of Patients Receiving CAR-T Cells
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Lymphomas Non-Hodgkin's B-Cell|Lymphoma, Small Lymphocytic|Mantle Cell Lymphoma|Central Nervous System Lymphoma|Diffuse Large B Cell Lymphoma|Follicular Lymphoma|Burkitt Lymphoma|Multiple Myeloma
Interventions: OTHER: Long-Term Follow-Up of Participants who Received CAR-T cells
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Malondialdehyde and Nitrous Oxide as Salivary Biomarkers for Different Oral Lesions
Status: COMPLETED
Conditions: Oral Lichen Planus|Oral Cancer|Leukoplakia|Oral Keratoses
Interventions: DIAGNOSTIC_TEST: salivary biomarker
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Participants With Guillain-Barré Syndrome (GBS)
Status: WITHDRAWN
Conditions: Guillain-Barré Syndrome
Interventions: DRUG: Crovalimab|DRUG: Placebo|DRUG: Intravenous immunoglobulin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Striatal Effective Connectivity to Predict Treatment Response in Cocaine Misuse
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: levodopa/carbidopa 400/100 BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Weekly Nanoparticle Albumin-Bound Paclitaxel (Abraxane) + Weekly Cetuximab + Radiation Therapy (IMRT, Intensity-Modulated Radiation Therapy) in Patients With Stage III-IVB Head and Neck Squamous Cell Carcinoma (HNSCC)
Status: COMPLETED
Conditions: HEAD & NECK Cancer
Interventions: OTHER: Cetuximab, IMRT, Albumin-bound paclitaxel (Abraxane®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Silodosin 8 mg Daily for the Treatment of Nocturia in Men With Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Nocturia|Prostatic Hyperplasia
Interventions: DRUG: silodosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nutrition Therapy in the Immature Infant (ImNuT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Immature Infant|Essential Fatty Acid Deficiency
Interventions: DIETARY_SUPPLEMENT: Formulaid|DIETARY_SUPPLEMENT: MCT-oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mobicox: Study of Meloxicam to Reduce Prostate Swelling in Permanent Seed Prostate Brachytherapy
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Meloxicam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ALK33-001: A Study of RDC-0313 Administered to Healthy Adults
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: RDC-0313|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: tDCS Combined With Constraint Induced Movement Therapy and Role of GABA Activity in Stroke Recovery
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: active anodal transcranial Direct Current Stimulation (tDCS)|DEVICE: sham transcranial Direct Current Stimulation|BEHAVIORAL: Constraint Induced Movement Therapy (CIMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: TICS: Transcranial Magnetic Stimulation for Intervening in Children With Tourette's Syndrome (CIHR)
Status: UNKNOWN
Conditions: Tic Disorders
Interventions: DEVICE: rTMS + CBIT|BEHAVIORAL: Sham rTMS + CBIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Infusion Impact on Chronic Pain Patients
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: Dexmedetomidine in 0.9 % NaCl 20 Mcg/5 mL (4 Mcg/mL) INTRAVEN SYRINGE (ML)|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intradermal Acupuncture Based on Changes in Biological Specificity of Acupoints for Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Basic treatment|PROCEDURE: PSA|PROCEDURE: TSA|PROCEDURE: CCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Hand MOtor Rehabilitation Using a sEMG-biofeedback
Status: COMPLETED
Conditions: Stroke|Stroke, Ischemic|Stroke Hemorrhagic|Hemiparesis
Interventions: DEVICE: REMO®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ebola CVD-Mali #2000 (Bivalent) VRC-EBOAdc069-00-vp (cAd3-EBO)
Status: COMPLETED
Conditions: Ebola Virus Disease|Hemorrhagic Fever
Interventions: BIOLOGICAL: VRC-EBOADC069-00-vp|BIOLOGICAL: VRC-EBOADC069-00-vp|BIOLOGICAL: MVA-EbolaZ|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: IvaBradinE to Treat MicroalbumiNuria in Patients With Type 2 Diabetes and Coronary Heart Disease
Status: WITHDRAWN
Conditions: Diabetic Kidney Disease
Interventions: DRUG: Ivabradine|OTHER: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dual Integrin αvβ3 and GRPR Targeting PET Imaging in Breast Cancer Patients
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: 68Ga-NOTA-BBN-RGD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Pembrolizumab (MK-3475) Plus Platinum and Gemcitabine as First Line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (PIPER)
Status: RECRUITING
Conditions: Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Pembrolizumab|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Stature Related Distress
Status: COMPLETED
Conditions: Idiopathic Short Stature|Self Image
Interventions: DRUG: GH treatment (Genotropin)|DRUG: 1 year treatment with placebo followed by optional 3 years of GH treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Maintenance Versus Observation After 6 Cycles of Gemcitabine Plus Paclitaxel in Pts With Advanced Breast Cancer
Status: COMPLETED
Conditions: Advanced Breast Cancer
Interventions: DRUG: gemcitabine , paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apple Cider Vinegar for the Prevention of Urinary Lithiasis (APUL)
Status: UNKNOWN
Conditions: Kidney Stones, Urolithiasis, Hypocitraturia
Interventions: DIETARY_SUPPLEMENT: Apple Cider Vinegar|DIETARY_SUPPLEMENT: Other Beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Healing Potentiality Of Blood Clot S-PRF and A-PRF in the Treatment Of Necrotic Mature Single-Rooted Teeth With Chronic Peri-Apical Periodontitis
Status: COMPLETED
Conditions: Necrotic Pulp
Interventions: PROCEDURE: Advanced Platelet Rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab for Locally Advanced, Irresectable, Non-metastatic dMMR Colorectal Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Long-term Safety, Tolerability and Effect of Daily Oral Laquinimod 0.6 mg on Disease Course in Subjects With Relapsing Multiple Sclerosis
Status: TERMINATED
Conditions: Relapsing Multiple Sclerosis
Interventions: DRUG: Laquinimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sulindac and Tamoxifen in Treating Patients With Desmoid Tumor
Status: COMPLETED
Conditions: Desmoid Tumor
Interventions: DRUG: tamoxifen citrate|DRUG: sulindac|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Trial of Bevacizumab in Combination With Pemetrexed
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer (NSCLC)|Lung Cancer|Neoplasm Metastasis
Interventions: DRUG: Bevacizumab|DRUG: Pemetrexed|DRUG: Vitamin B12|DRUG: Folate|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalency Study of Mycophenolate Mofetil 250 mg Capsules Under Fed Conditions
Status: COMPLETED
Conditions: Prophylaxis of Organ Rejection
Interventions: DRUG: mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation Of Two Bone-Anchored Maxillary Molar Distalization Appliances: Direct Versus Indirect Anchorage
Status: RECRUITING
Conditions: Maxillary First Molar Distalization
Interventions: DEVICE: Direct bone anchored pull distal slider|DEVICE: Indirect bone anchored dual force distalizer.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Edmonton Automated Sugar Intelligence - Intelligent Diabetes Management, EASI-IDM, App Program to Assist Diabetes Care
Status: COMPLETED
Conditions: Diabetes, Type 1
Interventions: BEHAVIORAL: EASI-IDM use
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Breast Pain Using A Medication (Diclofenac) Applied to the Skin
Status: TERMINATED
Conditions: Breast Pain|Non-cyclical Mastalgia|Surgical Scar-Related Breast Pain
Interventions: DRUG: Diclofenac|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Heparin on Femoral Arterial Sheaths Thrombosis During Diagnostic Coronary Angiography
Status: COMPLETED
Conditions: Diagnostic Coronary Angiography
Interventions: DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Anesthesia Technique on Post-operative Delirium After Transcatheter Aortic Valve Implantation
Status: UNKNOWN
Conditions: Delirium|Post-Op Complication|Anesthesia|Aortic Valve Disease
Interventions: PROCEDURE: anesthesia type
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial of Alternating 2',3'-Dideoxycytidine and Zidovudine in the Treatment of Patients With Advanced HIV Disease
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Zalcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wound Irrigation Comparative Effectiveness Study
Status: RECRUITING
Conditions: Cutibacterium Acnes Contamination
Interventions: PROCEDURE: Irrisept Irrigation|PROCEDURE: Saline Irrigation Solution Delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Isatuximab in Combination With REGN2810 (Cemiplimab) in Patients With Advanced Malignancies
Status: TERMINATED
Conditions: Prostate Cancer|Non-small Cell Lung Cancer
Interventions: DRUG: Isatuximab SAR650984|DRUG: Cemiplimab REGN2810
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prenatal Probiotic Intervention
Status: COMPLETED
Conditions: Childhood Obesity|Maternal Obesity During Childbirth|Insulin Resistance|Inflammation
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effects of 5HTP and LDOPA on CNS Excitability After SCI
Status: SUSPENDED
Conditions: Spinal Cord Injuries
Interventions: DRUG: 5HTP|DRUG: L-DOPA|DRUG: Placebo oral tablet|DRUG: Carbidopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of INFIX and Plating for Pelvic Ring Injuries With Symphysis Disruptions
Status: TERMINATED
Conditions: Anterior Pelvic Ring Injury With Symphysis Disruption
Interventions: PROCEDURE: Internal Fixator|PROCEDURE: Symphyseal Plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Active Break Intervention on Low Back Pain and Musculoskeletal Discomfort During Prolonged Sitting Among Young People
Status: COMPLETED
Conditions: Low Back Pain
Interventions: BEHAVIORAL: Active break with the proposed lumbar and hip extension exercises|BEHAVIORAL: Self-care recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraarterial Alteplase Versus Placebo After Mechanical Thrombectomy
Status: COMPLETED
Conditions: Stroke, Acute
Interventions: DRUG: Intraarterial alteplase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the Mirabegron Compared With Solifenacin in Treatment of Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Mirabegron 25mg|DRUG: Solifenacin Succinate 5 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tegafur Combined With Temozolomide Versus Tegafur Combined With Temozolomide and Thalidomide in Subjects With Advanced Pancreatic Neuroendocrine Tumor
Status: UNKNOWN
Conditions: Pancreatic Neuroendocrine Tumor
Interventions: DRUG: Tegafur and Temozolomide|DRUG: Tegafur and Temozolomide combined with Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep Health, Inflammation, and Emotion Study
Status: COMPLETED
Conditions: Depression
Interventions: BIOLOGICAL: Endotoxin|BEHAVIORAL: Partial sleep deprivation|OTHER: Placebo|OTHER: Uninterrupted sleep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Duvelisib Maintenance After Autologous Stem Cell Transplant in T-Cell Lymphomas
Status: ACTIVE_NOT_RECRUITING
Conditions: T-Cell Lymphoma
Interventions: DRUG: Duvelisib|PROCEDURE: Peripheral blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Long Chain Polyunsaturated Fatty Acids on Behavior and Cognition in Children With Attention Deficit Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DIETARY_SUPPLEMENT: Omega-3 fatty acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of a Peer-led Self-management Program for Recent-onset Psychosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Early Psychosis|Psychotic Disorders
Interventions: BEHAVIORAL: Peer-led self-management program|BEHAVIORAL: Psycho-education group|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Efficacy and Safety of SHR8008 vs. Fluconazole in Subjects With Acute Vulvovaginal Candidiasis
Status: UNKNOWN
Conditions: Acute Vulvovaginal Candidiasis
Interventions: DRUG: SHR8008 capsule|DRUG: Fluconazole capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influenza & COVID-19 Obstetric and Perinatal Epidemiology Study in India
Status: RECRUITING
Conditions: Influenza|COVID-19|SARS-COV-2 Infection|Other Respiratory Viruses|Perinatal Morbidity|Infant Morbidity
Interventions: OTHER: Exposures
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rituximab Hyaluronidase in Combination With Chemotherapy in Treating Aggressive B-cell Lymphoma in Uganda
Status: TERMINATED
Conditions: Burkitt Lymphoma|KSHV-associated Multicentric Castleman Disease|Diffuse Large B-Cell Lymphoma
Interventions: BIOLOGICAL: Rituximab and Hyaluronidase Human|DRUG: Cyclophosphamide|DRUG: Vincristine|DRUG: Methotrexate|DRUG: Doxorubicin|DRUG: Doxorubicin Hydrochloride|DRUG: Prednisone|DRUG: Etoposide|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficiency Study of BCMA-PD1-CART Cells in Relapsed/Refractory Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: BCMA-PD1-CART Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-dose Dexamethasone in Newly Diagnosed Pulmonary Sarcoidosis
Status: UNKNOWN
Conditions: Sarcoidosis
Interventions: DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)
Status: NOT_YET_RECRUITING
Conditions: T-cell Acute Lymphoblastic Leukemia|T-cell Lymphoma|Mixed Phenotype Acute Leukemia
Interventions: DRUG: Dexamethasone|DRUG: Vincristine|DRUG: Daunorubicin|DRUG: Calaspargase pegol|DRUG: Dasatinib|DRUG: Venetoclax|DRUG: Bortezomib|DRUG: Intrathecal triple therapy (methotrexate + hydrocortisone + cytarabine)|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Mercaptopurine|DRUG: Nelarabine|DRUG: Methotrexate|DRUG: Thioguanine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identifying Characteristics of Bone Marrow Failure Syndromes
Status: UNKNOWN
Conditions: Bone Marrow Failure Syndromes|Anemia, Aplastic|Myelodysplastic Syndromes|Hemoglobinuria, Paroxysmal|Red-Cell Aplasia, Pure|Purpura, Thrombocytopenic|Leukemia, Lymphocytic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Versus Late Deflation of Distal Tourniquet in IVRA With and Without Ketorolac in Hand & Forearm Surgery
Status: UNKNOWN
Conditions: Hand Injuries With Intravenous Regional Anesthesia
Interventions: DRUG: Group one ( lidocaine or control LE ) Early deflation|DRUG: Group two ( lidocaine , ketorolac LKE ) Early deflation|DRUG: Group three ( lidocaine or control LL ) Late deflation|DRUG: Group four ( lidocaine , ketorolac LKL ) Late deflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: HOP-3 Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone
Status: COMPLETED
Conditions: Healthy Males
Interventions: DRUG: Acyline|OTHER: placebo hCG (no active ingredient)|DRUG: hCG (human chorionic gonadotropin)|DRUG: hCG (human chorionic gonadotropin)|DRUG: hCG (human chorionic gonadotropin)|DRUG: Testosterone gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PSMA in Gastrointestinal Tumors (GIPSMA, Focusing on Neuroendocrine Neoplasms)
Status: RECRUITING
Conditions: Gastrointestinal Cancer
Interventions: RADIATION: 18F-PSMA PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Propionyl-L-Carnitine in the Treatment of Peripheral Arterial Disease (Intermittent Claudication)
Status: COMPLETED
Conditions: Peripheral Vascular Diseases|Intermittent Claudication
Interventions: DRUG: Propionyl-L-Carnitine|DRUG: PLC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Colesevelam HCl, Rosiglitazone, Sitagliptin on Control of Blood Glucose and Lipids in Type 2 Diabetes Patients Whose Blood Glucose Isn't Completely Controlled With Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes|Hyperlipidemia
Interventions: DRUG: Colesevelam HCl|DRUG: rosiglitazone maleate|DRUG: sitagliptin phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Microneedling and CTG for Gingival Augmentation- A RCT
Status: NOT_YET_RECRUITING
Conditions: Gingival Phenotype
Interventions: DEVICE: microneedling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Ipilimumab/Nivolumab for Patients With Recurrent, High Risk, Resectable Melanoma
Status: NOT_YET_RECRUITING
Conditions: Melanoma
Interventions: DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Treatment With and Without Protease Inhibitors for Women Who Begin Therapy for HIV Infection During Pregnancy
Status: COMPLETED
Conditions: HIV Infections|Pregnancy
Interventions: DRUG: Lamivudine|DRUG: Lamivudine/Zidovudine|DRUG: Nelfinavir mesylate|DRUG: Nevirapine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Physical Therapist Administered Physical Activity Intervention After Total Knee Replacement
Status: COMPLETED
Conditions: Physical Activity
Interventions: BEHAVIORAL: Standardize PT after TKR with a Physical Activity Intervention|OTHER: Standardized PT after TKR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Xaroban 20mg (Rivaroxaban) Tablet and Xarelto 20mg (Rivaroxaban) Tablet Under Fed Conditions
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Rivaroxaban 20 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Immunogenicity and Safety of Tetravalent Dengue Vaccine (TDV) Co-administered With an Hepatitis A Virus Vaccine
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: TDV|BIOLOGICAL: HAV Vaccine|BIOLOGICAL: TDV Placebo|BIOLOGICAL: HAV Vaccine Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: RSV-F Vaccine and Influenza Vaccine Co-Administration Study in the Elderly
Status: COMPLETED
Conditions: Respiratory Syncytial Virus (RSV)
Interventions: BIOLOGICAL: Low dose RSV-F Vaccine with Adjuvant (Day 0); Seasonal TIV (Day 0 & Day 28)|BIOLOGICAL: Low dose RSV-F Vaccine without Adjuvant (Day 0); Seasonal TIV (Day 0 & day 28)|BIOLOGICAL: High dose RSV-F Vaccine with Adjuvant (Day 0); Seasonal TIV (Day 0 & Day 28)|BIOLOGICAL: High dose RSV-F Vaccine without Adjuvant (Day 0); Seasonal TIV (Day 0 & Day 28)|BIOLOGICAL: Placebo (Day 0 & Day 28); Seasonal TIV (Day 0)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Beijing Osteoporosis With Neurological Disorders in Epigenetic Changes Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoporosis，Neurological Disorders
Interventions: COMBINATION_PRODUCT: Exercise，Nutrition，Bisphosphonates，Statins，Calcitonin,Vitamin D，et al.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of the Optimal Cocktailed Probiotics for Decolonization of Vancomycin-resistant Enterococci in Human Gut
Status: UNKNOWN
Conditions: Vancomycin-Resistant Enterococci|Probiotics
Interventions: DIETARY_SUPPLEMENT: probiotic cocktail capsules|DIETARY_SUPPLEMENT: placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Excision Limits of Oral Cavity Tumor by Narrow Band Imaging
Status: TERMINATED
Conditions: Cancer
Interventions: DEVICE: Location of the suspected lesions|PROCEDURE: Biopsy|PROCEDURE: Lesion excision/Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Model of Human Occupation-Based Intervention on Premenstrual Syndrome Symptoms
Status: COMPLETED
Conditions: Premenstrual Syndrome
Interventions: BEHAVIORAL: Occupational Therapy and Relaxation Group|BEHAVIORAL: Relaxation Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Sourcing Study to Collect Human Blood Samples From Healthy Adults
Status: COMPLETED
Conditions: Meningitis, Meningococcal
Interventions: BIOLOGICAL: rMenB+OMV NZ vaccine|BIOLOGICAL: Meningococcal Groups A, C, W and Y Conjugate Vaccine (MenACWY)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Explorative Efficacy Profile of Neurexan® in an Experimental Acute Stress Setting in Healthy Subjects
Status: COMPLETED
Conditions: Acute Stress Reaction
Interventions: DRUG: Neurexan®|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Switching to Tenofovir Alafenamide (TAF) From Tenofovir Disoproxil Fumarate (TDF) and/or Other Oral Antiviral Treatment (OAV)
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of the Oricol™ Sampling Device to Retrieve Vagina Mucus (Wall) Samples for Genomic & Epigenetic Analysis.
Status: COMPLETED
Conditions: Vagina Disease|Diagnosis
Interventions: DIAGNOSTIC_TEST: Quantification of human DNA retrieved and DNA fragmentation profile.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessing a Clinically-meaningful Opioid Withdrawal Phenotype
Status: RECRUITING
Conditions: Opioid Withdrawal|Opioid Use Disorder|Opioid Craving
Interventions: DRUG: Morphine|DRUG: Naloxone + lofexidine pretreatment|DRUG: Naloxone + placebo pretreatment|DRUG: Lofexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II
Status: RECRUITING
Conditions: Refractory Angina
Interventions: DEVICE: Arm 1: treatment with Neovasc Reducer|OTHER: Arm 2 (control): Implantation procedure with no device implanted|DEVICE: Arm 3 (unblinded, non-randomized): Single arm registry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Transversus Abdominis Plane Block in Patients Undergoing Total Abdominal Hysterectomy
Status: COMPLETED
Conditions: Abdominal Hysterectomy (& Wertheim)|Intraoperative Complications
Interventions: PROCEDURE: TAP block|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Xeloda and Bevacizumab to Treat Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: BIOLOGICAL: Bevacizumab|DRUG: capecitabine (Xeloda)|RADIATION: Rectal Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of Zolpidem Modified Release Formulation in Insomnia Patients
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders|Primary Insomnia
Interventions: DRUG: Zolpidem MR|DRUG: Estazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AIM2: Adequate Selection of Patients for Thyroid Biopsy: Evaluation of a Shared Decision Making Conversation Aid
Status: RECRUITING
Conditions: Thyroid Nodules|Thyroid Cancer
Interventions: BEHAVIORAL: Counseling using the electronic conversation aid|BEHAVIORAL: counseling by routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Clinical and Biological Umbrella Protocol for Smoker or Non-smoker Patients With OPML or HNSCC
Status: TERMINATED
Conditions: Premalignant Lesion|Head and Neck Squamous Cell Carcinoma (HNSCC)
Interventions: PROCEDURE: Samples collection|BEHAVIORAL: Psychological and Sociological evaluation|BEHAVIORAL: Intensive and sustained smoking cessation program|BEHAVIORAL: Tobacco and alcohol status follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION