pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Tango for Treatment of Motor and Non-motor Manifestations in Parkinson's Disease.
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: OTHER: Argentinean Tango classes|OTHER: Simple pamphlet about the exercise in PD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Akkermansia and Weight Maintenance
Status: COMPLETED
Conditions: Obesity|Microtia|Metabolic Syndrome|Weight Loss
Interventions: DIETARY_SUPPLEMENT: Akkermansia muciniphila|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Meibomian Gland Dysfunction Prior to Cataract Surgery
Status: COMPLETED
Conditions: Blepharitis|Dry Eye Syndrome
Interventions: DEVICE: LipiFlow Pre-Treatment|DEVICE: LipiFlow Post-treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety of a Novel Acellular Dermal Template as Treatment for Burns and Scars
Status: COMPLETED
Conditions: Full Thickness Skin Defects
Interventions: DEVICE: Novomaix dermal substitute in combination with STSG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cranial Radiotherapy or Intensive Chemotherapy With Hematopoietic Stem Cell Rescue for Primary Central Nervous System Lymphoma in Young Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Central Nervous System Lymphoma
Interventions: RADIATION: cranial radiotherapy|DRUG: intensive chemotherapy and hematopoietic stem cell rescue|DRUG: MTX based chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of AS012 in Subjects With Non-segmental Vitiligo
Status: COMPLETED
Conditions: Non-segmental Vitiligo
Interventions: DRUG: AS012|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Food Effect on the Safety, Tolerability, PK of EC-18 After Oral Administration in Healthy Volunteers
Status: COMPLETED
Conditions: Chemotherapy-Induced Neutropenia
Interventions: DIETARY_SUPPLEMENT: high-fat diet|DRUG: EC-18
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Study of GS-9911 With or Without Antibody Treatment for Adults With Solid Tumors
Status: RECRUITING
Conditions: Solid Tumors
Interventions: DRUG: GS-9911|DRUG: Zimberelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab (MK-3475) in Platinum Pre-treated Recurrent/Metastatic Nasopharyngeal Cancer (MK-3475-122/KEYNOTE-122)
Status: COMPLETED
Conditions: Nasopharyngeal Neoplasms
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Capecitabine|DRUG: Gemcitabine|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1a/1b Study to Determine the Recommended Phase 2 Dose, of Tepotinib in Participants With MET Alterations and Brain Tumors
Status: WITHDRAWN
Conditions: Brain Tumor
Interventions: DRUG: tepotinib|DRUG: tepotinib plus osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CD19 Targeted CAR T Cell Therapy in Adult Patients with Relapsed or Refractory B Cell Acute Lymphoblastic Leukaemia (ALL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Right Ventricular Dysfunction by Portal Vein Doppler After Cardiac Surgery
Status: COMPLETED
Conditions: Postoperative Complications|Heart Diseases|Heart Failure|Heart Valve Diseases
Interventions: OTHER: cardiac surgery involving mitral or tricuspid valve repair procedure, with cardiopulmonary bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: HPV Self-test to Increase Cervical Cancer Screening in Asian Women
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: BEHAVIORAL: Education on cervical cancer prevetnion|BEHAVIORAL: Dynamic group interaction|BEHAVIORAL: Physician engagement|BEHAVIORAL: Patient Navigation|BEHAVIORAL: General Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301
Status: NOT_YET_RECRUITING
Conditions: Sickle Cell Disease|Transfusion-dependent Beta-Thalassemia|Hemoglobinopathies
Interventions: OTHER: Safety and efficacy assessments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reducing High-Risk Geriatric Polypharmacy Via EHR Nudges R01 Trial
Status: ENROLLING_BY_INVITATION
Conditions: Polypharmacy
Interventions: BEHAVIORAL: Clinical decision support (CDS)-Commitment nudge|OTHER: Clinician education|BEHAVIORAL: Clinical decision support (CDS)-Justification nudge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Photosafety of BI 730357 Compared to Placebo and the Known Photosensitizing Agent Ciprofloxacin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 730357|DRUG: Placebo to match BI 730357|DRUG: Ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Search for a Link Between the Different Variables for Glycaemia and Oxidative Stress or Impaired HDL Function
Status: COMPLETED
Conditions: Type-1 Diabetes
Interventions: BIOLOGICAL: blood sample|BIOLOGICAL: urine sample|DEVICE: installation of Holter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study of the Efficacy and Safety of Topiramate in the Treatment fo Obese, Type 2 Diabetic Patients Treated With Metformin
Status: COMPLETED
Conditions: Obesity|Diabetes Mellitus, Type 2|Diabetes Mellitus, Adult-Onset
Interventions: DRUG: topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Trial Investigating the Efficacy and Safety of SCH 900435 (Org 25935) in Relapse Prevention in Participants With Alcohol Dependence (P05718)
Status: TERMINATED
Conditions: Alcoholism
Interventions: DRUG: SCH 900435|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Topiramate as add-on Therapy in the Treatment of Epilepsy Patients With Difficult to Treat, Partial-onset Seizures
Status: COMPLETED
Conditions: Epilepsy|Epilepsies, Partial|Seizures
Interventions: DRUG: topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Effect of Fuke Qianjin Capsule on Chronic Pelvic Pain Caused by Pelvic Inflammation
Status: UNKNOWN
Conditions: Chronic Pelvic Pain
Interventions: DRUG: Fuke Qianjin capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Platelets Rich Plasma Injection With PRGF Method in the Treatment for Osteoarthritis of the Subtalar Joint
Status: UNKNOWN
Conditions: Osteoarthritis of Subtalar Joint
Interventions: BIOLOGICAL: Platelet Rich Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving ToM in Children With ASD Through VPT Training: Behavioral and fNIRS Study
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Visual perspective taking training|BEHAVIORAL: Block building training|BEHAVIORAL: Thought-bubble training|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ADDERALL XR (Mixed Salts of a Single-entity Amphetamine) and STRATTERA ( Atomoxetine Hydrochloride) Compared to Placebo on Simulated Driving Safety and Performance and Cognitive Functioning in Adults With ADHD
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Mixed salts of a single-entity amphetamine|DRUG: Atomoxetine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of the Different Information Channels in Reducing Anxiety in Participants of Cervical Cancer Screening
Status: COMPLETED
Conditions: Uterine Cervical Neoplasms|Early Detection of Cancer|Anxiety|Clinical Trial
Interventions: OTHER: Audiovisual information|OTHER: Written information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Enhancing Physical Therapy Best Practice for Improving Walking After Stroke
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke|Cerebral Infarction|Brain Ischemia|Infarction, Brain
Interventions: BEHAVIORAL: Enhancing Physical Therapy Usual Care|BEHAVIORAL: Physical Therapy Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Individualization of Antineoplastic Drugs and Anti-Infective Drug in Children With Hematoplastic Disease
Status: UNKNOWN
Conditions: Hematological Neoplasms
Interventions: DRUG: Bortezomib|DRUG: Eltrombopag|DRUG: Imatinib|DRUG: dasatinib|DRUG: Pegaspargase|DRUG: Anti-Infective Drugs|DRUG: PEGylated Recombinant Human Granulocyte Colony-Stimulating Factor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of KRN23 in Adults With X-linked Hypophosphatemia (XLH)
Status: COMPLETED
Conditions: X-linked Hypophosphatemia
Interventions: BIOLOGICAL: burosumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phenylbutyrate Therapy for Maple Syrup Urine Disease
Status: COMPLETED
Conditions: Maple Syrup Urine Disease
Interventions: DRUG: Phenylbutyrate|DRUG: Placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation for Recurrent Hepatocellular Carcinoma With Twin Cooled-wet Electrodes
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Local Recurrence of Malignant Tumor of Liver
Interventions: PROCEDURE: Radiofrequency ablation using combined bipolar and monopolar energy deliver with Twin Cooled-Wet electrodes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Effectiveness of Local Ablathermy Radio Frequency Bronchial Tumors Primitive
Status: COMPLETED
Conditions: Malignant Non-small Cell Neoplasm of Lung Stage Ia
Interventions: PROCEDURE: Percutaneous radiofrequency ablation (RFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of Diazepam Buccal Film (DBF) in Subjects With Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Diazepam Buccal Soluble Film 5, 7.5,10, 12.5,15 or 17.5 mg with individual dose determined according to age and weight category
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Treat Major Depressive Disorder With a New Medication
Status: COMPLETED
Conditions: Depressive Disorder|Anhedonia
Interventions: DRUG: Ezogabine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Pharmacogenomics Testing in the Optimal Use of Supportive Care Medications in Stage III-IV Cancer
Status: COMPLETED
Conditions: Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8|Biliary Tract Carcinoma|Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Malignant Brain Neoplasm|Malignant Genitourinary System Neoplasm|Malignant Solid Neoplasm|Pancreatobiliary Carcinoma|Pathologic Stage III Cutaneous Melanoma AJCC v8|Pathologic Stage IIIA Cutaneous Melanoma AJCC v8|Pathologic Stage IIIB Cutaneous Melanoma AJCC v8|Pathologic Stage IIIC Cutaneous Melanoma AJCC v8|Pathologic Stage IV Cutaneous Melanoma AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage IV Breast Cancer AJCC v8|Stage III Colorectal Cancer AJCC v8|Stage III Ovarian Cancer AJCC v8|Stage III Pancreatic Cancer AJCC v8|Stage III Prostate Cancer AJCC v8|Stage IIIA Colorectal Cancer AJCC v8|Stage IIIA Ovarian Cancer AJCC v8|Stage IIIA Prostate Cancer AJCC v8|Stage IIIB Colorectal Cancer AJCC v8|Stage IIIB Ovarian Cancer AJCC v8|Stage IIIB Prostate Cancer AJCC v8|Stage IIIC Colorectal Cancer AJCC v8|Stage IIIC Ovarian Cancer AJCC v8|Stage IIIC Prostate Cancer AJCC v8|Stage IV Colorectal Cancer AJCC v8|Stage IV Ovarian Cancer AJCC v8|Stage IV Pancreatic Cancer AJCC v8|Stage IV Prostate Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVA Ovarian Cancer AJCC v8|Stage IVA Pancreatic Cancer|Stage IVA Prostate Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVB Ovarian Cancer AJCC v8|Stage IVB Pancreatic Cancer|Stage IVB Prostate Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Genetic Testing|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Cholesterol Disruption in Combination With the Standard of Care in Patients With Advanced Pancreatic Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma|Pancreatic Cancer|Pancreas Cancer|Metastatic Cancer
Interventions: DRUG: Cholesterol metabolism disruption
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of TCA vs. ECA for the Treatment of AIN in HIV-positive Patients
Status: COMPLETED
Conditions: Anal Intraepithelial Neoplasia (AIN) in HIV-infected Patients
Interventions: OTHER: Topical 85% trichloroacetic acid (TCA)|PROCEDURE: Surgical electrocautery (ECA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of 3 Diagnostic Strategies of PE: Planar V/Q Scan, CTPA, and V/Q SPECT.
Status: UNKNOWN
Conditions: Pulmonary Embolism
Interventions: DEVICE: Planar V/Q-based strategy|DEVICE: CTPA-based strategy|DEVICE: V/Q SPECT-based strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SedAting With Volatile Anesthetics Critically Ill COVID-19 Patients in ICU: Effects On Ventilatory Parameters And Survival
Status: RECRUITING
Conditions: Covid19|Hypoxic Respiratory Failure
Interventions: DRUG: Isoflurane Inhalant Product|DRUG: Sevoflurane inhalant product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-planning Mathematical Models in EUS-guided Laser Ablation of Pancreatic Lesions
Status: RECRUITING
Conditions: Pancreatic Neoplasms
Interventions: DEVICE: The medical device used in this study is a 980 nm wavelength diode laser with maximum output of 30 W (EUFOTON Laser Spectrum).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety And Efficacy Of Lenalidomide In Patients With Relapsed Or Refractory Aggressive Non-Hodgkin's Lymphoma (NHL)
Status: COMPLETED
Conditions: Non-Hodgkins Lymphoma
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Addition of Panitumumab to Chemoradiation Therapy in Patients With Locally Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Squamous Cell Carcinoma
Interventions: DRUG: Cisplatin|RADIATION: Standard Fractionation Radiotherapy|DRUG: Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manuka Honey in Preventing Esophagitis-Related Pain in Patients Receiving Chemotherapy and Radiation Therapy For Lung Cancer
Status: COMPLETED
Conditions: Dysphagia|Lung Cancer|Pain|Esophagitis
Interventions: DRUG: Manuka honey in liquid form|DRUG: Manuka honey in lozenge form|DRUG: Standard supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Biomarkers and Antithrombotic Treatment in Cervical Artery Dissection - TREAT-CAD
Status: COMPLETED
Conditions: Cervical Artery Dissection
Interventions: DRUG: Acetylsalicylic acid|DRUG: Vitamin K antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Re-volumizing Performance of Aliaxin (New Trademark)
Status: COMPLETED
Conditions: Malar and Sub-malar Volume Deficiency
Interventions: DEVICE: Aliaxin (new trademark - IBSA Farmaceutici Italia S.r.l.)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare Safety/Efficacy of Labeled vs Wait-Extend Regimen of Lucentis in Turkish Patients With VI Due to DME
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Labeled regime arm|DRUG: Wait and Extend regime arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Spirulina-Silicon Supplementation on the Morphological, Biomechanical and Functional Characteristics of the Arterial Wall in the Elderly
Status: COMPLETED
Conditions: Elderly
Interventions: DIETARY_SUPPLEMENT: 3.5g of spirulina per day in 1% silicone|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gene Therapy for ADA-SCID Using an Improved Lentiviral Vector (Ivlv-ADA)
Status: RECRUITING
Conditions: Adenosine DeAminase Severe Combined ImmunoDeficiency (ADA-SCID)
Interventions: GENETIC: Direct intravenous injection of ivlv-ADA lentiviral vector
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study Comparing How Well Different Doses of the Medicine NN0519-0130 Help People With Excess Body Weight Lose Weight
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: DRUG: NNC0519-0130|DRUG: Placebo|DRUG: Tirzepatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Stent Versus Direct Atherectomy to Treat Lower Limb Ischemia
Status: COMPLETED
Conditions: Atherosclerosis|Ischemia
Interventions: DEVICE: plaque excision system|DEVICE: Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Parallel, Double-blind, Placebo-controlled Study of Vitamin D as Prophylactic Treatment for Migraine
Status: COMPLETED
Conditions: Migraine According to International Headache Society (IHS) Criteria (ICHD-II)
Interventions: DRUG: D3 Vitamin ®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: ZOSTAVAX(R) Local Registration Trial (V211-019)
Status: COMPLETED
Conditions: Varicella Virus Infection
Interventions: BIOLOGICAL: Zoster Vaccine, Live, (Oka-Merck)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Incretin and Treatment With Inhibition of Sodium-glucose Cotransporter-2 Combination Insights Into Mechanisms Implicated in Congestive Heart Failure: "NATRIURETIC" Trial
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Empagliflozin 25 MG + Liraglutide 1.8 MG|DRUG: Liraglutide 1.8 MG + Empagliflozin 25 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ES101 (PD-L1x4-1BB Bispecific Antibody) in Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Solid Tumors|Neoplasms|Malignant Tumor
Interventions: DRUG: ES101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Two Dıfferent Technıques Used in Psychomotor Skılls Traınıng on Nursıng Students
Status: COMPLETED
Conditions: Anxiety|Clinical Decision-making|Simulation Training|Nursing Students
Interventions: OTHER: Computer-assisted simulation technique training group|OTHER: Imagery GROUP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Continuing Lamivudine vs Switching to Entecavir in Patients With Detectable HBV DNA
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Entecavir|DRUG: Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Ciprofol Anesthesia on Learning and Memory Function and Antidepressant Effects of ECT in Depressive Patients
Status: NOT_YET_RECRUITING
Conditions: Depressive Disorder
Interventions: DRUG: ciprofol|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of GWP42003-P for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults
Status: COMPLETED
Conditions: Epilepsy|Lennox Gastaut Syndrome
Interventions: DRUG: GWP42003-P|DRUG: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patellar Resurfacing Under Subvastus Approach in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Osteoarthritis, Patella Resurfacing
Interventions: PROCEDURE: Patella resurfacing|PROCEDURE: Patella retention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Controlled Trial for Pain Relief After Office Ureteral Stent Removal
Status: COMPLETED
Conditions: Pain|Urinary Stone|Urinary Calculi
Interventions: DRUG: Ketorolac|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Two Different Lightwand Intubation Techniques in Cervical Immobilized Patients
Status: COMPLETED
Conditions: Intubation; Difficult or Failed
Interventions: PROCEDURE: Face-to-face approach|PROCEDURE: Conventional approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Pharmacokinetic Study of Pediatric Subjects With Tinea Cruris and Tinea Pedis
Status: COMPLETED
Conditions: Tinea Pedis|Tinea Cruris
Interventions: DRUG: NAFT500 (pediatric)|DRUG: NAFT600 (pediatric)|DRUG: NAFT500 (adult)|DRUG: NAFT600 (adult)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Explore the Effects of Virtual Reality Natural Environment of Older People
Status: RECRUITING
Conditions: Older People
Interventions: BEHAVIORAL: Stage 1 Experimental A group: actual natural environment|BEHAVIORAL: Stage 1 Experimental B group: virtual reality natural environment|BEHAVIORAL: Stage 1 Control group: city environment|BEHAVIORAL: Stage 2 group|BEHAVIORAL: Stage 3 Experimental group: virtual reality natural environment|BEHAVIORAL: Stage 3 Control group: routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Drug Transporter Interaction Study PHENTRA_2015_KPUK
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: pitavastatin|DRUG: Metformin|DRUG: digoxin|DRUG: Adefovir|DRUG: sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Probiotics Prophylaxis of Urinary Tract Infections in Children
Status: UNKNOWN
Conditions: Prevention of Urinary Tract Infections in Children
Interventions: OTHER: Placebo control group|DIETARY_SUPPLEMENT: Probiotic experimental group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Post-exercise Nutrition on Glycemia in Women
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Greek yogurt|BEHAVIORAL: Carbohydrate-based study supplement|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telomere Length in Human Polar Body and Telomere Length in Cumulus Cells: A Clinical Validation Study
Status: UNKNOWN
Conditions: Telomere Length
Interventions: GENETIC: First polar body biopsy in MII oocytes|GENETIC: PGT-A blastocyst
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Biochemical and Histological Comparison of Nasal and Auricular Cartilage in the Fetus and Newborn With Cleft Lip Carrier
Status: UNKNOWN
Conditions: Newborn Cleft Lip and Slot Carrier
Interventions: OTHER: Measurements of concentration of hyaluronic acid as well as in type 1 collagen and 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Descemet Stripping (Automated) Endothelial Keratoplasty (DSEK or DSAEK)
Status: COMPLETED
Conditions: Corneal Dystrophies, Hereditary
Interventions: PROCEDURE: Descemet Stripping Automated Endothelial Keratoplasty (DSAEK)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ELASTANCE: Prospective Physiological Study of Lung Elastance in Recruitment and Derecruitment in Early Onset Mechanically Ventilated ARDS Patients
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome
Interventions: PROCEDURE: Measure lung and chest wall elastance with esophageal catheter|OTHER: non-invasive method for measuring the lung elastance
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Influence of Soft Tissue Thickness on the Bone Level Around Implants
Status: COMPLETED
Conditions: Tooth Loss
Interventions: PROCEDURE: Xenogeneic collagen matrix (XCM) graft augmentation|PROCEDURE: Connective tissue graft augmentation (CTG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Practice of Acceptance, Awareness, and Compassion in Caregiving (PAACC)
Status: COMPLETED
Conditions: Dementia
Interventions: BEHAVIORAL: PAACC|BEHAVIORAL: REACH-VA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Aminoacidemia and Protein Kinetics in Response to the Ingestion of Plant-based Protein Blends
Status: ACTIVE_NOT_RECRUITING
Conditions: Nutrition, Healthy
Interventions: DIETARY_SUPPLEMENT: Protein quality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TURN-COVID Biobank: The Dutch Cohort Study for the Evaluation of the Use of Neutralizing Monoclonal Antibodies and Other Antiviral Agents Against SARS-CoV-2
Status: RECRUITING
Conditions: COVID-19
Interventions: DRUG: casirivimab with imdevimab|DRUG: sotrovimab|DRUG: molnupiravir
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: T-Cell Mitochondrial Respiration Response to Ketone Monoester Supplement in Healthy Volunteers and COVID-19
Status: WITHDRAWN
Conditions: COVID-19 Acute Respiratory Distress Syndrome
Interventions: DIAGNOSTIC_TEST: Agilent Seahorse XF Cell Mito Stress Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Common Safety Follow-up Trial of Tecemotide (L-BLP25)
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer|Multiple Myeloma
Interventions: BIOLOGICAL: Tecemotide|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two Pneumatic Compression Devices in the Treatment of Lower Extremity Lymphedema
Status: TERMINATED
Conditions: Lymphedema
Interventions: DEVICE: Flexitouch System|DEVICE: Hydroven FPR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enoxaparin Thromboprophylaxis in Cancer Patients With Elevated Tissue Factor Bearing Microparticles
Status: COMPLETED
Conditions: Advanced Pancreatic, Colon, Lung, Gastric and Ovarian Cancer
Interventions: DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CC-5013 Plus Dexamethasone Versus Dexamethasone Alone in Previously Treated Subjects With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: CC-5013|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 6-TG, Capecitabine and Celecoxib Plus TMZ or CCNU for Anaplastic Glioma Patients
Status: COMPLETED
Conditions: Anaplastic Glioma of Brain|Glioblastoma Multiforme|Brain Cancer
Interventions: DRUG: Capecitabine|DRUG: Celecoxib (Celebrex)|DRUG: Temozolomide|DRUG: Lomustine|DRUG: 6-Thioguanine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical BPM31510 3.0% Cream in Patients With Epidermolysis Bullosa
Status: COMPLETED
Conditions: Epidermolysis Bullosa
Interventions: DRUG: topical BPM31510 3.0% Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telephone Case Monitoring (TCM) for Veterans With Post-Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Telephone monitoring|OTHER: Treatment-As-Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cannabis Impairment Detection Application (CIDA)
Status: COMPLETED
Conditions: Driving Under the Influence|Marijuana Intoxication|Alcohol Intoxication
Interventions: DRUG: Cannabis (THC) (Inhaled) Placebo|DRUG: Cannabis (High% THC) (Inhaled)|DRUG: Cannabis (Very High% THC) (Inhaled)|DRUG: Alcohol (oral)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimizing Pharmacologic Treatment for Neonatal Opioid Withdrawal Syndrome (OPTimize NOW): A Symptom-Based Dosing Approach
Status: RECRUITING
Conditions: Neonatal Opiate Withdrawal Syndrome
Interventions: OTHER: Symptom-based Dosing Approach|OTHER: Scheduled Opioid Taper Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Intervention Educational Program on the Quality of Life of Patients With Hip Fracture
Status: COMPLETED
Conditions: Hip Fractures|Quality of Life
Interventions: BEHAVIORAL: Postoperative Intervention Educational Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study To Determine The Safety, Tolerability, Skin Irritation Potential, And PK Following Topical Application Of PF-07038124 In Healthy Participants
Status: COMPLETED
Conditions: Dermatitis Atopic
Interventions: DRUG: PF-07038124 and Vehicle|DRUG: PF-07038124 or vehicle|DRUG: PF-07038124 or vehicle|DRUG: PF-07038124 or vehicle|DRUG: PF-07038124 or vehicle|DRUG: PF-07038124 or vehicle|DRUG: PF-07038124 or vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanistic Pathways of Mindfulness Meditation in Post-traumatic Stress Disorder.
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorders
Interventions: BEHAVIORAL: Slow Breathing|BEHAVIORAL: Meditation|BEHAVIORAL: Meditation and slow breathing|BEHAVIORAL: Sitting Quietly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial of HIV-1 C4-V3 Polyvalent Peptide Vaccine in HIV-1 Infected Persons
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: HIV-1 C4-V3 Polyvalent Peptide Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Phase 4 Comparative Trial of Benzathine Penicillin G for Treatment of Early Syphilis in Subjects With or Without HIV Infection
Status: COMPLETED
Conditions: Syphilis
Interventions: DRUG: Benzathine Penicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Perioperative Painting Art Therapy (LOM® Solution Centered Art Therapy) in Surgical Patients
Status: UNKNOWN
Conditions: Lower Gastrointestinal Neoplasms Benign|Pancreas Cancer|Posttraumatic Stress Disorder|Depression, Anxiety
Interventions: BEHAVIORAL: perioperative painting art therapy (LOM® solution centered art therapy)|BEHAVIORAL: perioperative painting art therapy (LOM® solution centered art therapy) - control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Application of Virtual Reality Exposure Versus Relaxation Training in Music Performance Anxiety
Status: RECRUITING
Conditions: Music Performance Anxiety
Interventions: BEHAVIORAL: Virtual Reality Exposure Therapy (VRET)|BEHAVIORAL: Progressive Muscle Relaxation (PMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Soy Bread on Markers of Bone Metabolism and Cardiovascular Disease
Status: COMPLETED
Conditions: Osteoporosis|Cardiovascular Diseases
Interventions: BEHAVIORAL: Soy bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Varenicline for Light Smokers
Status: COMPLETED
Conditions: Smoking
Interventions: DRUG: Varenicline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Behavioral Economics to Improve Treatment of Acute Respiratory Infections (Pilot Study)
Status: COMPLETED
Conditions: Acute Respiratory Infections (ARIs)
Interventions: BEHAVIORAL: Clinical Decision Support: Accountable Justification|BEHAVIORAL: Audit and Feedback: Peer Comparison|BEHAVIORAL: CDS Order Sets: Suggested Alternatives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Observing the Effect of Fascial Manipulation in Athletes With Shin Splits.Tibial Stress Syndrome.
Status: COMPLETED
Conditions: Shin Splint|Fascial Manipulation|Running Kinematics
Interventions: OTHER: Fascial manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ramelteon for the Treatment of Insomnia and Mood Stability in Patients With Euthymic Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Ramelteon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Identifing Risk Factors for Pancreaticojejunostomy Leakage Following Pancreaticoduodenectomy
Status: UNKNOWN
Conditions: Pancreatic Fistula|Whipple Operation|Pancreaticoduodenectomy|POPF
Interventions: PROCEDURE: Pancreaticoduodenectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mild Hypothermia After Endovascular Treatment in Acute Ischemic Stroke
Status: UNKNOWN
Conditions: Ischemic Stroke|Thrombolytic Therapy
Interventions: DEVICE: Arctic Sun|OTHER: Standard treatment|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Capecitabine With or Without Vaccine Therapy in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: sargramostim|BIOLOGICAL: telomerase peptide vaccine GV1001|DRUG: capecitabine|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab (RTX) for Disease Modifying Anti Rheumatic Drug (DMARD) Non-responders in Pakistan: The Pakistan Rituximab Study (PARIS)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy Study of Evofosfamide in Combination With Ipilimumab
Status: UNKNOWN
Conditions: Pancreatic Cancer|Melanoma|Squamous Cell Carcinoma of the Head and Neck|Prostate Cancer
Interventions: DRUG: Evofosfamide|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Perineural and Systemic Effect of Dexamethasone for Interscalene Brachial Plexus Block.
Status: UNKNOWN
Conditions: Analgesia
Interventions: DRUG: Dexamethasone|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PI3-Kinase Inhibitor GDC-0941 in Combination With Paclitaxel, With and Without Bevacizumab or Trastuzumab, and With Letrozole, in Participants With Locally Recurrent or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Bevacizumab|DRUG: Pictilisib|DRUG: Letrozole|DRUG: Paclitaxel|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Platelet Function After Statin Loading Dose in Patients Before Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Platelet Dysfunction
Interventions: DRUG: Atorvastatin|DRUG: Rosuvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Rifampin on the Single-dose Pharmacokinetics of BMS-986177 in Healthy Subjects
Status: COMPLETED
Conditions: Thrombosis
Interventions: DRUG: BMS-986177|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multi-Center Clinical Evaluation of Two Daily Disposable Contact Lenses
Status: COMPLETED
Conditions: Myopia|Refractive Error
Interventions: DEVICE: Ultrafilcon B contact lens|DEVICE: Stenfilcon A contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of an (Omicron Subvariant) COVID-19 Vaccine Booster Dose in Previously Vaccinated Participants and Unvaccinated Participants.
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: XBB.1.5 Vaccine (Booster)|BIOLOGICAL: XBB.1.5 Vaccine (single dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized Phase 2 Study of AT-101 in Combination With Docetaxel in Relapsed/Refractory Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: AT-101 and docetaxel|DRUG: placebo and docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stopping Heavy Periods Project
Status: UNKNOWN
Conditions: Abnormal Uterine Bleeding|Abnormal Uterine Bleeding, Ovulatory Dysfunction|Abnormal Uterine Bleeding, Endometrial Hemostatic Dysfunction
Interventions: DEVICE: Levonorgestrel intrauterine system|DRUG: Combined oral contraceptives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of TENS on Postoperative Pain and Quality of Life After Inguinal Hernia Repair
Status: COMPLETED
Conditions: Inguinal Hernia|Postoperative Pain|Quality of Life|Transcutaneous Electric Nerve Stimulation
Interventions: DEVICE: Transcutaneous electric nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of TB511 in Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: NSCLC|Prostate Cancer|Colorectal Cancer|Hepatocellular Carcinoma
Interventions: DRUG: TB511|DRUG: Keytruda
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise in Testicular Germ Cell Cancer Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Testicular Germ Cell Tumor
Interventions: BEHAVIORAL: aerobic-strength exercise intervention (6-months)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Incorporating Acupuncture Into ERAS for Ambulatory Total Hip Replacement (THR) Surgery
Status: RECRUITING
Conditions: Acupuncture|Hip Surgery|Opioid Use
Interventions: DEVICE: Auricular Trauma Protocol (ATP) Acupuncture|OTHER: No Acupuncture Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Assessment of Simultaneous Administration of Clopidogrel and Aspirin
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Cloas|DRUG: Plavix/Astrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT