pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: DEP Combine With PD-1 Antibody as an Treatment for EBV-HLH
Status: UNKNOWN
Conditions: Hemophagocytic Lymphohistiocytosis
Interventions: DRUG: DEP combine with PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Systemic Exposure to VP-102 in Subjects With Molluscum Contagiosum.
Status: COMPLETED
Conditions: Molluscum Contagiosum
Interventions: COMBINATION_PRODUCT: VP-102 with applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ANI and NoL Index Variations After Standard Nociceptive Stimulus at 0, 50, 25 % of Inhaled N2O in the Anesthetic Mixture
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: N2O exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the Blood
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Quizartinib|DRUG: Fludarabine|DRUG: Cytarabine|DRUG: Intrathecal (IT) triple chemotherapy prophylaxis|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ultrasound-guided Suprascapular Nerve Block Versus Intra-articular Corticosteroid Injection for Frozen Shoulder
Status: COMPLETED
Conditions: Frozen Shoulder
Interventions: PROCEDURE: SCNB group|PROCEDURE: IACI group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ticagrelor With or Without Atorvastatin on Endothelial Function in Healthy Males
Status: COMPLETED
Conditions: Ischemia
Interventions: DRUG: Atorvastatin|DRUG: Placebo|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Tislelizumab With Chemotherapy for the Treatment of MSS Colon Cancer
Status: RECRUITING
Conditions: Colonic Neoplasms|Neoadjuvant Therapy|Immune Checkpoint Inhibitors
Interventions: DRUG: Tislelizumab|DRUG: Oxaliplatin|DRUG: Capecitabine|PROCEDURE: Colectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benzo[a]Pyrene Ultralow Dose-Response Study
Status: COMPLETED
Conditions: Environmental Exposure
Interventions: DRUG: [14C]-benzo[a]pyrene
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Methotrexate For The Prevention and Treatment of Proliferative Vitreoretinopathy in Pediatric Patients
Status: WITHDRAWN
Conditions: Proliferative Vitreoretinopathy
Interventions: DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Stem Cell Therapy for Treatment of Female Stress Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence, Stress
Interventions: BIOLOGICAL: Stem Cells,Mesenchymal|PROCEDURE: surgery (TVT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2a Clinical Trial of PR001 (LY3884961) in Patients With Parkinson's Disease With at Least One GBA1 Mutation (PROPEL)
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: BIOLOGICAL: LY3884961|DRUG: Methylprednisolone|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis in Pediatric Subjects
Status: COMPLETED
Conditions: Mydriasis|Dilation
Interventions: DRUG: Phentolamine Ophthalmic Solution 0.75%|DRUG: Phentolamine Ophthalmic Solution Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utilizing Protein During Weight Loss to Impact Physical Function and Bone
Status: COMPLETED
Conditions: Obesity|Weight Loss|Diet Modification|Aging|Weight Change, Body|Dietary Habits|Osteopenia, Osteoporosis|Bone Loss|Fractures, Bone
Interventions: BEHAVIORAL: Weight loss intervention months 0-6|BEHAVIORAL: Exercise intervention months 0-6|DIETARY_SUPPLEMENT: NutraBio™ CarboMax Supplement|DIETARY_SUPPLEMENT: 6-month NutraBio™ 100% Whey Protein Isolate Supplement|DIETARY_SUPPLEMENT: 18-month NutraBio™ 100% Whey Protein Isolate Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intramyocellular Fatty Acid Trafficking in Insulin Resistance States - Effects of Intestinal Delivery of Lipids
Status: RECRUITING
Conditions: Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Intralipid|DIETARY_SUPPLEMENT: Palm Oil Emulsion|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effectiveness of Cervical Kinesio Taping in Migraine
Status: RECRUITING
Conditions: Migraine|Kinesio Taping
Interventions: OTHER: Kinesio taping|OTHER: Exercise|OTHER: Sham taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Training and Brain Stimulation in Prodromal Alzheimer's Disease
Status: COMPLETED
Conditions: Subjective Cognitive Decline|Mild Cognitive Impairment
Interventions: DEVICE: anodal tDCS|BEHAVIORAL: Intensive cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of PDC-1421 Capsule to Evaluate the Safety and Efficacy in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: PDC-1421 Capsule|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Bioequivalence of Doxylamine+Pyridoxine and Diclectin
Status: COMPLETED
Conditions: Nausea
Interventions: DRUG: Doxylamine + Pyridoxine|DRUG: Diclectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: HR070803 in Combination With Oxaliplatin, S-1 Versus NALIRIFOX as Adjuvant Therapy for Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Efficacy and Safety
Interventions: DRUG: HR070803|DRUG: Oxaliplatin|DRUG: Tegafur|DRUG: Folinic acid|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of an Adapted Antibiotherapy in Hurley Stage 2 Hidradenitis Suppurativa Patients
Status: NOT_YET_RECRUITING
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: ROCEPHIN, metronidazole, RIFADIN, IZILOX, placebo combination therapy|DRUG: Lymecyclin and corresponding placebos of the experimental arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Pharmacokinetics, Safety and Tolerability of HIP1502
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: varenicline tartrate 1mg (HGP1604, R) - varenicline oxalate 1mg (HIP1502, T), RT|DRUG: varenicline oxalate 1mg (HIP1502, T) - varenicline tartrate 1mg (HGP1604, R), TR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Therapy to Drive Nerve Regeneration
Status: NOT_YET_RECRUITING
Conditions: Peripheral Nerve Injuries
Interventions: DEVICE: Acute Intermittent Hypoxia|DEVICE: Normoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Stability of the Medial Pivot Total Knee Prosthesis
Status: COMPLETED
Conditions: Osteoarthritis of Knee
Interventions: DEVICE: Medacta GMK posterior stabilized prosthesis|DEVICE: Medacta GMK Sphere prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Initial Fixation of Bisphosphonate-coated Dental Implants
Status: UNKNOWN
Conditions: Pre-integration Failure of Dental Implant
Interventions: DEVICE: Zoledronate-coated dental implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phenotyping of Chronic Pain in Diffused Systemic Scleroderma
Status: COMPLETED
Conditions: Scleroderma, Systemic|Scleroderma, Diffuse
Interventions: OTHER: QST, CPM and Paisudoscan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Preoperative Rehabilitation on Tendon Healing and Bone Mineral Density After ACLR
Status: NOT_YET_RECRUITING
Conditions: Anterior Cruciate Ligament Rupture
Interventions: BEHAVIORAL: exercise rehablitation|BEHAVIORAL: routine treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An International Study to Evaluate Recombinant Interleukin-2 in HIV Positive Patients Taking Anti-retroviral Therapy
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Recombinant interleukin-2 (rIL-2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of pH Values of the Embryo Culture Medium on Success of In Vitro Fertilization (IVF)
Status: RECRUITING
Conditions: Embryo Growth Disorder|Humans|Pregnancy
Interventions: PROCEDURE: pH at 7.38 ± 0.02|PROCEDURE: pH at 7.22 ± 0.02
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety Study of a Vitamin E Supplement in Normal Volunteers and Those With Both Allergy and Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Vitamin E supplement rich in gamma tocopherol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Comparison of Steroid Dosages on the Efficacy of Trochanteric Bursa Injection
Status: COMPLETED
Conditions: Bursitis
Interventions: DRUG: Kenalog
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fentanyl Sublingual Spray for Exercise-Induced Breakthrough Dyspnea
Status: COMPLETED
Conditions: Advanced Cancers
Interventions: DRUG: Fentanyl Sublingual Spray|PROCEDURE: Shuttle Walk Test|BEHAVIORAL: Questionnaires|BEHAVIORAL: Mental Ability Tests|BEHAVIORAL: Phone Call
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Confocal Laser Endomicroscopy Nodule Localization by Robotic Bronchoscopy
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Neoplasms
Interventions: DEVICE: nCLE aided RANB biospy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multiple Dose Study Of PF-05231023 In Adult Subjects Who Have Poor Lipid Control With And Without Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Melliuts, Type 2
Interventions: OTHER: Placebo|DRUG: 25 mg PF-05231023|DRUG: 50 mg PF-05231023|DRUG: 100 mg PF-05231023|DRUG: 150 mg PF-05231023
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aromatherapy in Total Knee Replacement
Status: COMPLETED
Conditions: Total Knee Replacement|Post-operative Nausea and Vomiting|Opioid Use|Anxiety|Depression|Post Operative Pain
Interventions: OTHER: Elequil Lavender-peppermint Aromatabs|OTHER: Elequil Almond-Oil Aromatabs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Intra Articular Injections With Platelet Rich Plasma in Patients With Juvenile Osteochondritis Dissecans of the Knee
Status: COMPLETED
Conditions: Osteochondritis Dissecans
Interventions: DRUG: Platelet rich plasma (PRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: tDCS on Motor Rehabiliation of Post Stroke Patients
Status: COMPLETED
Conditions: Stroke|Transcranial Direct Current Stimulation
Interventions: DEVICE: Anodal tDCS|BEHAVIORAL: Physical therapy|DEVICE: Cathodal tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability, and Pharmacokinetics of E2082 in Healthy Male Subjects
Status: TERMINATED
Conditions: Healthy Participants
Interventions: DRUG: E2082|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chinese Herbal Medicine and Micronized Progesterone for Live Births in Threatened Miscarriage
Status: UNKNOWN
Conditions: Threatened Miscarriage
Interventions: DRUG: Chinese Herbal Medicine plus Progesterone Capsules|DRUG: Chinese Herbal Medicine Placebo plus Progesterone Capsules Placebo|DRUG: Chinese Herbal Medicine plus Progesterone Capsules Placebo|DRUG: Chinese Herbal Medicine Placebo plus Micronized Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Educational Intervention to Adopt SLT as First-Line Glaucoma Treatment
Status: COMPLETED
Conditions: Primary Open-angle Glaucoma
Interventions: OTHER: Patient Educational Intervention|OTHER: Usual Care|OTHER: Ophthalmologist Educational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Corneal Endothelial Cell Injury Induced by Mitomycin-C
Status: UNKNOWN
Conditions: Myopia
Interventions: PROCEDURE: Transepithelial PRK/MMC|PROCEDURE: Alcohol-Assisted PRK/MMC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intravascular Ultrasound Versus Angiography Guided Drug-coated Balloon Treatment for STEMI Patients：a Prospective, Multicenter, Randomized Controlled Trial
Status: UNKNOWN
Conditions: STEMI
Interventions: DEVICE: IVUS-guide DCB PTCA|DEVICE: Angio-guide DCB PTCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Physiological Study on Downregulation of EGF-receptors in the Skin by Topical Exposition With EGF
Status: UNKNOWN
Conditions: Plaque Psoriasis
Interventions: DRUG: Human recombinant epidermal growth factor|OTHER: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Physical Therapy Intervention Targeting Sitting and Reaching for Young Children With Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: BEHAVIORAL: START-Play Physical Therapy|BEHAVIORAL: Usual Care Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N99-01: Combination Chemotherapy, Radiation Therapy, and Stem Cell Transplantation in Treating Patients With Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: etoposide|DRUG: melphalan|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: iobenguane I 131|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of Prefabricated Adjustable Thermoplastic Mandibular Advancement Devices for Obstructive Sleep Apnoea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: mandibular advancement device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of LV Assist Device to Treat Patients With Cardiogenic Shock (ISAR-SHOCK)
Status: COMPLETED
Conditions: Shock, Cardiogenic|Myocardial Infarction
Interventions: DEVICE: Left Ventricular Assist Device Impella LP 2.5|DEVICE: Intraaortic Balloon Pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neural Correlates of Early Intervention for Posttraumatic Stress Disorder (PTSD)
Status: TERMINATED
Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: DRUG: paroxetine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ALA-PDT Versus Vehicle PDT for Treatment of AK and Reduction of New NMSC in Solid Organ Transplant Recipients
Status: TERMINATED
Conditions: Actinic Keratoses|Skin Neoplasms
Interventions: DRUG: Aminolevulinic Acid|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hatha Yoga Exercises in Pelvic and Lumbar Back Pain in Pregnant Woman
Status: COMPLETED
Conditions: LUMBAR BACK PAIN|PELVIC PAIN|PREGNANCY
Interventions: BEHAVIORAL: hatha yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Groin Sentinel Node Biopsy and 18FDG-PET/CT in cN0 Vulvar Cancer Patients Candidate to Standard Lymphadenectomy
Status: UNKNOWN
Conditions: Vulvar Cancer
Interventions: PROCEDURE: 18FDG-PET/TC|PROCEDURE: Sentinel node biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thoracoscopic Sympathetic Chain Interruption for Palmar Hyperhidrosis in Patients Below 18
Status: COMPLETED
Conditions: Hyperhidrosis|Children, Adolescents|Thoracoscopic Sympathetic Chain Interruption|Sympathetic Disorder
Interventions: PROCEDURE: Thoracoscopic sympathectomy|PROCEDURE: Thoracoscopic sympathotomy|PROCEDURE: Thoracoscopic sympathetic chain clipping
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Perioperative Sintilimab and Chemotherapy in Esophageal Squamous Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Sintilimab|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Appropriateness of Methodist Health System(MHS) Inter-facility Transfers of Traumatic Intracranial Subarachnoid Hemorrhage and Spontaneous Bleeds for Level-1 Advanced Surgical Intervention
Status: RECRUITING
Conditions: Traumatic Intracranial Subarachnoid Hemorrhage
Interventions: OTHER: rate of appropriate and inappropriate transfers from Methodist interfacility transfers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Influence of Conditional Workout Postpartum on Arterial Stiffness Among Women With Status After Preeclampsia, Superimposed Preeclampsia or HELLP-syndrome
Status: COMPLETED
Conditions: Preeclampsia|Superimposed Preeclampsia|HELLP Syndrome
Interventions: BEHAVIORAL: conditional workout
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Obatoclax Mesylate (GX15-070MS) for the Treatment of Hematological Malignancies
Status: COMPLETED
Conditions: Hematological Malignancies
Interventions: DRUG: Obatoclax mesylate (GX15-070MS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Precision Irradiation in Early NSCLC and Interstitial Lung Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer|Interstitial Lung Disease
Interventions: RADIATION: Stereotactic Ablative Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Bladder Stimulation Technique and Bathing Method on Urine Collection in Term Babies
Status: COMPLETED
Conditions: Urine Specimen Collection
Interventions: OTHER: Control|OTHER: The bladder stimulation technique|OTHER: Bath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Immunogenicity of 7-Valent Pneumococcal Conjugate Vaccine in Lung Fluid of Adults With and Without HIV Infection
Status: COMPLETED
Conditions: Pneumonia|Meningitis|Invasive Pneumococcal Disease|HIV
Interventions: BIOLOGICAL: 7-valent pneumococcal conjugate vaccine (Prevnar)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Efficacy and Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Major Depressive Disorder|Depression
Interventions: DRUG: TC-5214|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Ascending Dose Phase I Study of DBPR108 in Healthy Male Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: DBPR108|DRUG: matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Ciclo 21® Effect (Levonorgestrel + Ethinyl Estradiol) Compared to Nordette®.
Status: COMPLETED
Conditions: Irregular Periods
Interventions: DRUG: LNG+EE2|DRUG: Nordette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Patients With Anxiety Disorder (0777-022)
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: MK0777|DRUG: Comparator: placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study to Assess Acute Toxicity and Quality of Life of Patients With Carcinoma of the Anal Canal Receiving Chemotherapy and Radiation Using Helical Tomotherapy
Status: UNKNOWN
Conditions: Anal Canal Cancer
Interventions: RADIATION: Tomotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Effect of Low-Concentration Atropine Combined With Auricular Acupoint Stimulation in Myopia Control
Status: COMPLETED
Conditions: Myopia
Interventions: DRUG: Atropine|DEVICE: auricular acupoint stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Trial of Localized Radiation Therapy to Inhibit Restenosis (GAMMA V)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: GAMMA-Iridium-192 catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effect of Acid-reducing Agent Famotidine on the Drug Levels of BMS-986256 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986256|DRUG: Famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Quetiapine Plus Topiramate for Reducing Cannabis Consumption and Bipolar Mania
Status: COMPLETED
Conditions: Bipolar Disorder|Cannabis-Related Disorder
Interventions: DRUG: Quetiapine and placebo|DRUG: Quetiapine and Topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cediranib Maleate in Treating Patients With Recurrent or Newly Diagnosed Metastatic Head and Neck Cancer
Status: COMPLETED
Conditions: Recurrent Hypopharyngeal Squamous Cell Carcinoma|Recurrent Laryngeal Squamous Cell Carcinoma|Recurrent Laryngeal Verrucous Carcinoma|Recurrent Lip and Oral Cavity Squamous Cell Carcinoma|Recurrent Metastatic Squamous Cell Carcinoma in the Neck With Occult Primary|Recurrent Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma|Recurrent Nasopharyngeal Keratinizing Squamous Cell Carcinoma|Recurrent Oral Cavity Verrucous Carcinoma|Recurrent Oropharyngeal Squamous Cell Carcinoma|Recurrent Salivary Gland Carcinoma|Salivary Gland Squamous Cell Carcinoma|Squamous Cell Carcinoma Metastatic in the Neck With Occult Primary|Stage IV Hypopharyngeal Squamous Cell Carcinoma|Stage IV Laryngeal Squamous Cell Carcinoma|Stage IV Laryngeal Verrucous Carcinoma|Stage IV Lip and Oral Cavity Squamous Cell Carcinoma|Stage IV Major Salivary Gland Carcinoma|Stage IV Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma|Stage IV Nasopharyngeal Keratinizing Squamous Cell Carcinoma|Stage IV Oral Cavity Verrucous Carcinoma|Stage IV Oropharyngeal Squamous Cell Carcinoma|Tongue Carcinoma|Untreated Metastatic Squamous Cell Carcinoma to Neck With Occult Primary
Interventions: DRUG: Cediranib Maleate|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study, Performed in Subjects With Post Traumatic-post Surgical ,Venus Insufficiency and Diabetic Hard to Heal/Chronic Wounds, to Evaluate the Safety and Efficacy of PolyHeal-2 Versus PolyHeal in Once Daily Regimen
Status: TERMINATED
Conditions: Surgical Wound Dehiscence
Interventions: DEVICE: PolyHeal 2|DEVICE: Polyheal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antagonization of Heparin With Protamine Sulfate After TAVI
Status: NOT_YET_RECRUITING
Conditions: Aortic Valve Stenosis|Heart Valve Diseases
Interventions: DRUG: Antagonization of heparin with protamine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Colostrum Applications Every 2 Hours and 4 Hours In Order to Achieve Trophic Feeding in Preterm Infants
Status: COMPLETED
Conditions: Trophic Feeding|Very Low Birth Weight Baby|Preterm
Interventions: PROCEDURE: Oral colostrum application 2 hours|PROCEDURE: Oral colostrum application 4 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Impact of MABT5102A on Brain Amyloid Load and Related Biomarkers in Patients With Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: MABT5102A|DRUG: MABT5102A|DRUG: placebo|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CRUSH PAD: Real-world Outcomes Following Use of the Shockwave Intravascular Lithotripsy (IVL) Technology in Calcified Common Femoral Lesions
Status: RECRUITING
Conditions: Femoral Arterial Calcification|Peripheral Arterial Disease|Claudication|Critical Limb Ischemia
Interventions: DEVICE: Shockwave Intravascular Lithotripsy (IVL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I Clinical Study Trial of Felbinac Trometamol Injection in China
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Felbinac Trometamol Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Evaluation After Anterior Cruciate Ligament (ACL) Ligamentoplasty
Status: COMPLETED
Conditions: Arthroscopic Anterior Cruciate Ligament Reconstruction
Interventions: PROCEDURE: "All-inside"|PROCEDURE: Classical technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Drug Interaction Study Between Eltrombopag and Lopinavir/Ritonavir in Healthy Adult Subjects.
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Eltrombopag|DRUG: Lopinavir/Ritonavir|DRUG: Eltrombopag and Lopinavir/Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Virtual Reality in the Upper Extremity Rehabilitation of Hemiparetic Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy, Spastic
Interventions: OTHER: Virtual Reality Therapy|OTHER: Conventional Physiotherapy|OTHER: Activity Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Buprenorphine on Postoperative Endodontic Analgesia
Status: TERMINATED
Conditions: Postoperative Pain
Interventions: DRUG: Buprenorphine|DRUG: Sterile saline|DRUG: lidocaine, epinephrine (Local anesthetic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telemedicine as a Means to Achieving Good Diabetes Control Among Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Poor Glycemic Control|Medication Adherence
Interventions: BEHAVIORAL: Telemedicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Combined Versus Separate Injections in People With Overweight or Obesity
Status: COMPLETED
Conditions: Obesity & Overweight
Interventions: DRUG: Cagrilintide|DRUG: semaglutide|DRUG: Cagrilintide and semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Platinum-based Chemotherapy for Patients With Resectable , Non-small Cell Lung Cancer With Switch to Chemotherapy Alternative in Nonresponders (NEOSCAN)
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: pemetrexed|DRUG: cisplatin|DRUG: Carboplatin|DRUG: Gemcitabine Hydrochloride|DRUG: Vinorelbine Tartrate|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b Study of Gemcitabine and Nab-paclitaxel in Combination With IM156 in Patients With Advanced Pancreatic Cancer.
Status: RECRUITING
Conditions: Pancreas Cancer
Interventions: DRUG: Gemcitabine|DRUG: Nab paclitaxel|DRUG: IM156
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study Comparing Lorazepam and Diazepam for Children in the Emergency Department With Seizures (Status 2)
Status: COMPLETED
Conditions: Status Epilepticus
Interventions: DRUG: lorazepam or diazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CBD for Pain Reduction and Opioid Use After Ankle and Tibia Fracture ORIF
Status: WITHDRAWN
Conditions: Ankle Fractures|Tibia Fracture
Interventions: DRUG: CBD|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Slimming Myokines, Cancers,Nutritional and Psychology Support
Status: UNKNOWN
Conditions: Cancer
Interventions: OTHER: psychological support|OTHER: nutritional education|OTHER: psychological support and nutritional education|OTHER: no intervation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rasburicase Versus Allopurinol in Tumor Patients at Risk for Hyperuricemia and Tumor Lysis Syndrome
Status: COMPLETED
Conditions: Tumor Lysis Syndrome|Cancer|Hyperuricemia
Interventions: DRUG: Rasburicase (SR29142)|DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SEALLS (Sealing Evaluation of Air Leaks After Lung Surgery) Trial Using HEMOPATCH
Status: COMPLETED
Conditions: LUNG DISEASES
Interventions: DEVICE: Hemopatch™ Sealing Hemostat|PROCEDURE: Standard surgical technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Stroke Prevention in Young Adults With Sickle Cell Anemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Sickle Cell Disease|Sickle Cell Anemia|Stroke, Ischemic|Silent Stroke|Silent Cerebral Infarct|Stroke
Interventions: DRUG: Hydroxyurea therapy per standard care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nasturtium (Tropaeolum Majus L) Intake and Biochemical Parameters in Pre-diabetic Subjects in Bogota Colombia
Status: COMPLETED
Conditions: Pre Diabetes
Interventions: DIETARY_SUPPLEMENT: Nasturtium (Tropaeolum majus)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Medical Thoracoscopy for Diagnosing Unexplained Pleural Effusion: a National Multicenter Retrospective Study
Status: NOT_YET_RECRUITING
Conditions: Pleural Effusion|Pleural Effusion, Malignant|Fibrinous Pleuritis
Interventions: PROCEDURE: Medical thoracoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tap Block vs Peritoneal Infiltration After Major Gynecological Surgeries
Status: COMPLETED
Conditions: Pain, Acute
Interventions: PROCEDURE: Transversus Abdominis Plane Block(TAP Block)|PROCEDURE: Intra-peritoneal infiltration|DRUG: PCIA Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Yttrium Y 90 Ibritumomab Tiuxetan, Etoposide, Cyclophosphamide, and an AHSCT in Non-Hodgkin's Lymphoma Patients
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: etoposide|PROCEDURE: AHSCT|RADIATION: yttrium Y 90 ibritumomab tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers.
Status: RECRUITING
Conditions: Solid Tumor|Haematological Malignancy|Melanoma|Thyroid Cancer, Papillary|Ovarian Neoplasms|Colorectal Neoplasms|Laryngeal Neoplasms|Carcinoma, Non-Small-Cell Lung|Glioma|Multiple Myeloma|Erdheim-Chester Disease|Thyroid Carcinoma, Anaplastic
Interventions: DRUG: Vemurafenib|DRUG: Cobimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Camrelizumab Combined With TCb Versus TCb in Neoadjuvant Treatment of Triple-negative Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Triple Negative Breast Cancer|Camrelizumab
Interventions: DRUG: （Carrelizumab + TCb） regimen|DRUG: TCb regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PPI Supplementation to Fight ECtopIc Calcification in PXE
Status: RECRUITING
Conditions: Pseudoxanthoma Elasticum
Interventions: DIETARY_SUPPLEMENT: study treatment PPI|DIETARY_SUPPLEMENT: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of "Smart" Body-Weight Scales for Weight and Nutritional Monitoring in Patients With Head and Neck Cancer Undergoing Radiation Therapy
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma|Malignant Head and Neck Neoplasm
Interventions: OTHER: Medical Device Qardio® smart scale Usage and Evaluation|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigation of the Effect of Acceptance and Commitment Therapy-Based Intervention in Oncology Patients
Status: NOT_YET_RECRUITING
Conditions: Acceptance and Commitment Therapy
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy-Based Intervention for Oncology Patients|BEHAVIORAL: Psychoeducation for Oncology Patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Role of Perhexiline in Hypertrophic Cardiomyopathy
Status: UNKNOWN
Conditions: Hypertrophic Cardiomyopathy
Interventions: DRUG: Perhexiline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of PLD Combined With Carboplatin Versus Paclitaxel Plus Carboplatin in the First-line Treatment of Epithelial Ovarian Cancer
Status: UNKNOWN
Conditions: Efficacy and Safety
Interventions: DRUG: pegylated liposomal doxorubicin|DRUG: paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality Improvement Project - "My Logbook! - I Know my Way Around!"; ("Mein Logbuch - Ich Kenne Mich Aus!")
Status: COMPLETED
Conditions: Brain Tumor|Neurofibromatoses|Sarcoma|Leukemia|Hematologic Diseases|Neuroblastoma
Interventions: OTHER: "My Logbook! - I know my way around!"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tactile/Kinaesthetic Massage Therapy on DXA Parameter of Preterm Infants
Status: COMPLETED
Conditions: Preterm Infant|Body Composition|Dual X-ray Absorptiometry (DXA) Scan
Interventions: PROCEDURE: Massage Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pharmacokinetics of Efavirenz in the Presence of Rifampicin and Isoniazid
Status: UNKNOWN
Conditions: HIV
Interventions: DRUG: Efavirenz|DRUG: tenofovir /emtricitabine|DRUG: tenofovir/lamivudine|DRUG: lamivudine/zidovudine|DRUG: Rifinah or local generics
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sirolimus vs Mycophenolate With Tacrolimus in Simultaneous Pancreas and Kidney Transplantation
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Sirolimus Oral Product|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Magnetic Resonance in Non Ischemic Cardiomyopathy
Status: UNKNOWN
Conditions: Cardiac Magnetic Resonance Imaging in Non Ischemic Cardiomyopathy
Interventions: DIAGNOSTIC_TEST: Cardiac magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cross-over Double-blind Intervention to Investigate the Effects of Defined Antioxidant-containing Drinks on Time Course of Antioxidant Capacity
Status: UNKNOWN
Conditions: The Impact of Vitamin c and Epicatechin Upon Antioxidant Capactity
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Vitamin C|DIETARY_SUPPLEMENT: epicatechin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fecal Microbiota Transplantation for the Prevention of Acute Graft Versus Host Disease in Adults Undergoing Allogeneic Hematopoietic Cell Transplantation
Status: RECRUITING
Conditions: Acute Graft Versus Host Disease|Hematopoietic and Lymphatic System Neoplasm
Interventions: DRUG: Fecal Microbiota Transplantation Capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acute Effects of 3,4-methylenedioxymethamphetamine (MDMA) With and Without a Booster Dose
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: MDMA 120 mg + MDMA 60 mg|DRUG: MDMA 120 mg + placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Memory-like Natural Killer (NK) Cell Therapy With N-803 in Patients With Renal Cell Carcinoma or Urothelial Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Renal Carcinoma|Renal Cell Carcinoma|Urothelial Carcinoma
Interventions: BIOLOGICAL: Cytokine Induced Memory-like Natural Killer (CIML NK) Cells|BIOLOGICAL: N-803
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study to Determine the Maximum Tolerated Dose and to Assess the Safety and Pharmacokinetic Profile of HM781-36B in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumor
Interventions: DRUG: HM781-36B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Passive Heat Therapy for Lowering Systolic Blood Pressure and Improving Vascular Function in Mid-life and Older Adults
Status: RECRUITING
Conditions: Aging
Interventions: OTHER: Heat therapy|OTHER: Thermoneutral water immersion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Heated Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Peritoneal Cancer
Status: COMPLETED
Conditions: FIGO Stage IIC-IV Ovarian Carcinoma|Fallopian Tube Carcinoma|Peritoneal Carcinoma
Interventions: DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corneal Crosslinking for Treatment of Corneal Neovascularization
Status: RECRUITING
Conditions: Corneal Neovascularization
Interventions: COMBINATION_PRODUCT: 30 minute photoactivation of riboflavin 0.1%|COMBINATION_PRODUCT: 10 minute photoactivation of riboflavin 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Investigate the Use of a New Syringe "Visual Pressure Control (VPC)" for Epidural Anesthesia in Children Surgery
Status: UNKNOWN
Conditions: Abdominal Hernia|Abdominal Wall Defect|Abdominal Neoplasm|Urogenital Disease|Urologic Neoplasms|Thoracic Diseases|Lung Diseases
Interventions: DEVICE: VPC syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Child Patient End-of-Life Care Module
Status: NOT_YET_RECRUITING
Conditions: Pediatric Asthma
Interventions: OTHER: control group (skill laboratory), experimental group 1 (Banner model) and experimental group2 (augmented reality mobile application)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Role of Whey and Lupin in Glycemic Control (Nutritional Pre-Study)
Status: COMPLETED
Conditions: Whole Body Glucose and Insulin Metabolism
Interventions: DIETARY_SUPPLEMENT: Lupin Protein|DIETARY_SUPPLEMENT: Whey Protein|OTHER: Reference
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT