pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clinical Utility of Olfactory Rehabilitation: Treatment for Pacients With Neurosensorial Anosmia
Status: COMPLETED
Conditions: Anosmia|Occupational Therapy|Brain Injuries, Traumatic
Interventions: BEHAVIORAL: olfactory rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Purified Anthocyanin and Nonalcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: Anthocyanin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of HRS-4642 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation
Status: RECRUITING
Conditions: Advanced KRAS G12D Mutant Solid Tumors
Interventions: DRUG: HRS-4642
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1 Antibody Combined With mXELIRI Versus mXELIRI in the Second-line Setting for ESCC
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma Abdominal Stage 0
Interventions: DRUG: PD-1 Inhibitors|DRUG: Irinotecan|DRUG: Capecitabine tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Tetrahydrocannabinol on Ocular Hemodynamics in Healthy Subjects
Status: COMPLETED
Conditions: Retinal Blood Flow
Interventions: DRUG: Dronabinol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Zenith(R) Fenestrated Abdominal Aortic Aneurysm (AAA) Endovascular Graft Clinical Study
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysms|Aorto-iliac Aneurysms|Juxtarenal Aneurysms
Interventions: DEVICE: Zenith(R) Fenestrated AAA Endovascular Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of VIR-2218 With or Without Pegylated Interferon Alpha-2a for Treatment of Chronic Hepatitis B Virus Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Hepatitis B
Interventions: DRUG: VIR-2218|DRUG: pegylated interferon-alfa 2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First in Human Single Ascending Dose Study of MOR107
Status: TERMINATED
Conditions: Safety
Interventions: DRUG: MOR107|DRUG: Placebo|OTHER: Low sodium diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tackling Pressure Ulcer Via Bee Venom Phonophoresis
Status: COMPLETED
Conditions: Bee Venom|Pressure Ulcers|Phonophoresis
Interventions: OTHER: group 1 received topical Bee venom gel|OTHER: Group 2: Phonophoresis of Bee Venom gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Trunk Stability Exercises on Hand Function in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: conservative physiotherapy plan|OTHER: trunk stability exercise plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peanut Protein Supplementation to Augment Muscle Growth and Improve Markers of Muscle Quality and Health in Young Adults
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Peanut protein powder|BEHAVIORAL: Full body resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Class IV Laser Therapy and Pilates Exercises on Bone Density and Pain in Primary Osteoporosis: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Osteoporosis
Interventions: RADIATION: laser therapy|OTHER: exercise|OTHER: combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Buyang Huanwu Decoction and Normal Tension Glaucoma
Status: NOT_YET_RECRUITING
Conditions: Glaucoma|Visual Acuity|Visual Field|Chinese Medicine
Interventions: COMBINATION_PRODUCT: Buyang Huanwu Decoction|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of New Biomarkers to Promote Personalized Treatment of Patients With Inflammatory Rheumatic Diseases
Status: RECRUITING
Conditions: Arthritis, Rheumatoid|Psoriatic Arthritis|Axial Spondyloarthritis|Connective Tissue Diseases|Gout
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Absorption, Distribution, Metabolism and Excretion (ADME) Study of Single Oral Dose [14C] GSK2118436 in Subjects With BRAF Mutant Solid Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: GSK2118436
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplant (FMT) Capsule for Improving the Efficacy of Anti- PD-1
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastrointestinal System Cancer
Interventions: BIOLOGICAL: FMT capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomised, Double-blind, Placebo-controlled to Assess the Efficacy and Safety of the Food Supplement Microsmin® Plus
Status: NOT_YET_RECRUITING
Conditions: Haemorrhoids
Interventions: DIETARY_SUPPLEMENT: diosmin and micronized flavonoids|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Artificial Intelligence (AI) on the Quality of Upper Gastrointestinal (GI) Endoscopy
Status: NOT_YET_RECRUITING
Conditions: Endoscopy, Digestive System
Interventions: DEVICE: Cerebro endoscopy quality control tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Rifasutenizol (TNP 2198) in Participants With H. Pylori Infection
Status: COMPLETED
Conditions: H.Pylori Infection
Interventions: DRUG: Rifasutenizol capsules|DRUG: Rabeprazole sodium enteric-coated tablets|DRUG: Amoxicillin Capsules|DRUG: Clarithromycin placebo tablets|DRUG: Bismuth potassium citrate placebo capsules|DRUG: Clarithromycin tablets|DRUG: Bismuth potassium citrate capsules|DRUG: Rifasutenizol placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Glabellar Frown Lines
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: DRUG: IncobotulinumtoxinA (Xeomin) (20 Units)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Hypoallergenicity of an Extensively Hydrolyzed Formula
Status: COMPLETED
Conditions: Cow Milk Allergy
Interventions: DIETARY_SUPPLEMENT: Extensively Hydrolyzed formula|DIETARY_SUPPLEMENT: Amino acid formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Breathing Exercise Applied With Incentive Spirometer
Status: COMPLETED
Conditions: Breathing Exercises|Cardiac Surgery|Incentive Spirometry
Interventions: OTHER: The post-surgical breathing exercise group|OTHER: The pre- and post- surgical breathing exercise group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Benefit of 3-D Planning in Total Hip Replacement. A Prospective Randomized Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Hip Injuries|Surgery|Prosthesis User
Interventions: DEVICE: SPS monoblock stem, Symbios|DEVICE: Quadra-H, Medacta|PROCEDURE: 3D planning of THR|PROCEDURE: 2D planning of THR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Molecular and Genetic Abnormalities in Patients With Myeloid Neoplasms
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myeloproliferative Neoplasms|Myelodysplastic Syndromes|Myeloproliferative/Myelodysplastic Neoplasm
Interventions: DRUG: Induction Chemotherapy|DRUG: Consolidation Chemotherapy|DRUG: Autologous Stem Cell Transplantation|DRUG: Allogeneic Stem Cell Transplantation|DRUG: Low Dose Cytarabine|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Validation Study of the Eximis CS (Contained Segmentation) System
Status: NOT_YET_RECRUITING
Conditions: Laparoscopic Gynecological Surgical Procedures
Interventions: DEVICE: Eximis CS (Contained Segmentation) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Prevention of Asthma With Levocetirizine (36 Month Treatment) in Young Children Suffering From Eczema (Atopic Dermatitis) and Sensitized to Grass Pollen and House Dust Mite and Having Completed the Previous EPAAC Trial (NCT00152464)
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: LEVOCETIRIZINE|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DIAgnostics for Multidrug Resistant Tuberculosis in Africa
Status: COMPLETED
Conditions: Tuberculosis, Multidrug-Resistant
Interventions: DIAGNOSTIC_TEST: Deeplex test, MolBio TrueNat for 2nd line, GeneXpert 2nd line|DIAGNOSTIC_TEST: Fluorescein DiAcetate (FDA) Microscopy,GeneXpert Ct value, pre-rRNA synthesis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Of The Safety And Efficacy Video Assisted Submandibular Gland Resection Using A New Two Step Technique
Status: COMPLETED
Conditions: Submandibular Gland Resection
Interventions: PROCEDURE: video assisted submandibular sialadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NIRS to Diagnose SAMS
Status: UNKNOWN
Conditions: Statin Adverse Reaction|Skeletal Myopathy
Interventions: DRUG: Simvastatin 20 mg|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Comparison of Large vs. Small Diameter Esophageal Stents for Palliation of Malignant Dysphagia
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DEVICE: Self-expandable metal stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid in Knee Joint Surgery
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Tranexamic Acid|DRUG: Normal saline (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Search to Advance Limited Use of Opioids Pilot: Optimization of Non-Opioid Therapy With a Steroid
Status: RECRUITING
Conditions: Pain Management
Interventions: DRUG: Dexamethasone 8mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Electrical Dry Needling Versus Iontophoresis in Treating Chronic Unilateral Knee Osteoarthritis
Status: RECRUITING
Conditions: Osteoarthritis of Knee
Interventions: OTHER: conventional physical therapy|OTHER: Electrical Dry Needling|OTHER: Glucosamine sulfate iontophoresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Effectiveness of GP0116
Status: ACTIVE_NOT_RECRUITING
Conditions: Skin Manifestations
Interventions: DEVICE: GP0116|DEVICE: Active Comparator: FDA approved dermal filler device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Daily Sedative Interruption in Critically Ill Patients Being Managed With a Sedation Protocol
Status: COMPLETED
Conditions: Critical Illness
Interventions: PROCEDURE: Protocolized Sedation|PROCEDURE: Protocolized sedation, with daily interruption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Role of Nocturnal Non-Invasive Ventilation in Pulmonary Rehabilitation
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: non invasive ventilation (Resmed VPAP III ST-A, Respironics Harmony)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Intensity Laser Therapy Versus Scapular Stabilization Exercises on Ventilatory Function in Forward Head Posture
Status: COMPLETED
Conditions: Forward Head Posture
Interventions: OTHER: Postural advice|OTHER: Traditional exercise treatment|OTHER: Scapular stabilization exercises|OTHER: High intensity Laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Endoscopy First" or "Laparoscopic Cholecystectomy First" for Patients With Intermediate Risk of Choledocholithiasis
Status: UNKNOWN
Conditions: Choledocholithiasis
Interventions: PROCEDURE: endoscopic ultrasound|PROCEDURE: intraoperative cholangiography|PROCEDURE: ERCP|DEVICE: Ultrasound endoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Body Compartment Pharmacokinetics of Anti- Retroviral Agents That May be Used for Future HIV Post- Exposure Prophylaxis.
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Single dose of Genvoya® and a single 800 mg dose of Darunavir®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Observe the Effectiveness of Empagliflozin, Other SGLT-2 Inhibitors, or DPP-4 Inhibitors in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Subjects treated with Empagliflozin or any Sodium-glucose cotransporter-2 (SGLT-2) inhibitor|DRUG: Subjects treated with Dipeptidyl peptidase-4 (DPP-4) inhibitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Open-label, Single-dose Trial to Assess the Pharmacokinetics of Centanafadine Extended-release Capsules in Pediatric Participants With Attention-deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Centanafadine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Stimulation for Improving Cognition in Chronic Stroke (NEPTUNE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Stroke
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Hip Arthroplasty Positioning Improvement Study
Status: UNKNOWN
Conditions: Osteoarthritis, Hip|Osteoarthritis|Arthritis|Musculoskeletal Diseases or Conditions
Interventions: PROCEDURE: Corin Optimised Positioning System|PROCEDURE: Standard templating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of CAN-2409 Immunotherapy During Active Surveillance for Prostate Cancer (ULYSSES)
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: aglatimagene besadenovec|BIOLOGICAL: placebo|DRUG: valacyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Clinical Trial of Exendin-4 in Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer's Disease|Mild Cognitive Impairment
Interventions: DRUG: Exendin-4 SC|DRUG: Placebo SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Lumbar Erector Spinae Plane Block for Hip Arthroplasty at the L4 Interspace
Status: TERMINATED
Conditions: Hip Arthropathy|Regional Anesthesia
Interventions: PROCEDURE: Ultrasound-guided Erector Spinae Plane Block with Ropivacaine 0.375%|DRUG: Ropivacaine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Carboplatin and Combination Chemotherapy With or Without Veliparib in Treating Patients With Stage IIB-IIIC Breast Cancer
Status: COMPLETED
Conditions: Estrogen Receptor-negative Breast Cancer|HER2-negative Breast Cancer|Progesterone Receptor-negative Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Triple-negative Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of MLN0128 in Metastatic Anaplastic Thyroid Cancer and Incurably Poorly Differentiated or Radioidodine Refractory Differentiated Thyroid Cancer
Status: COMPLETED
Conditions: Anaplastic Thyroid Cancer|Thyroid Cancer|Differentiated Thyroid Cancer
Interventions: DRUG: MLN0128
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Strain Change Study for SARS-CoV-2 rS Vaccines
Status: NOT_YET_RECRUITING
Conditions: Severe Acute Respiratory Syndrome Coronavirus 2 Infection
Interventions: BIOLOGICAL: NVX-CoV2705 Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Psychological Support for Patients With an Implantable Cardioverter Defibrillator
Status: COMPLETED
Conditions: Anxiety|Depression
Interventions: BEHAVIORAL: Cognitive Behaviour Therapy (CBT)|OTHER: Usual Cardiac Care (UCC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on Knee Immobilization and Pain Levels After an Anterior Cruciate Ligament (ACL) Reconstruction Surgery
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: DEVICE: knee immobilization splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Degree of Temperature on Levobupivacaine Spinal Anesthesia
Status: UNKNOWN
Conditions: Spinal Anesthetic Toxicity
Interventions: DRUG: Levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gemcitabine Hydrochloride, Cyclophosphamide, Vincristine Sulfate, Prednisolone, and Rituximab in Treating Patients With Newly Diagnosed Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: gemcitabine hydrochloride|DRUG: prednisolone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extent of Breast Cancer and the Role of Pre-Operative Sonography and MRI
Status: COMPLETED
Conditions: Ductal Breast Carcinoma In Situ|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer
Interventions: PROCEDURE: Contrast-enhanced Magnetic Resonance Imaging|PROCEDURE: Mammography|PROCEDURE: Therapeutic Conventional Surgery|PROCEDURE: Ultrasonography|PROCEDURE: Ultrasonography|OTHER: Gadolinium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Grasping Rehabilitation Using Motor Imagery With or With no Neurofeedback After Tetraplegia
Status: RECRUITING
Conditions: Individuals With C6-C7 Tetraplegia (AIS A or B)
Interventions: BEHAVIORAL: Motor imagery combined with neurofeedback (MINF)|BEHAVIORAL: Motor imagery (MI)|BEHAVIORAL: Control (C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Bleeding on Brushing Using Neem Extract Mouthwash Versus Chlorhexidine Mouthwash
Status: UNKNOWN
Conditions: Gingival Bleeding
Interventions: DRUG: Azadirachta indica|DRUG: Chlorhexidine mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Exercise and Nutritional Prehabilitation for Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: BEHAVIORAL: Physical Activity|BEHAVIORAL: Nutrition Counseling|BEHAVIORAL: Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of Different Doses of 90Y-hPAM4 Combined With Gemcitabine in Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: IMMU-107 (hPAM4)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ondansetron on Spinal Anesthesia in Caesarean Section
Status: UNKNOWN
Conditions: Hypotension
Interventions: DRUG: Ondansetron 4mg|DRUG: Ondansetron 8mg|DRUG: 100ml normal saline 0.9 percent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of the Bausch + Lomb Myopia Control Lens for the Correction of Myopic Ametropia and Slowing the Progression of Myopia in Children
Status: RECRUITING
Conditions: Myopia
Interventions: DEVICE: Bausch + Lomb (kalifilcon A) Myopia Control Soft (Hydrophilic)|DEVICE: CooperVision MiSight (omafilcon A/60%) Myopia Control one day Soft Contact Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Calcitriol on Biomarkers in Diabetic Kidney Disease Patients
Status: UNKNOWN
Conditions: Diabetic Kidney Disease
Interventions: DRUG: Calcitriol capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of APTO-253 in Patients With Relapsed or Refractory AML or MDS
Status: TERMINATED
Conditions: Acute Myelogenous Leukemia in Relapse|Acute Myelogenous Leukemia, Relapsed, Adult|Acute Myelogenous Leukemia, Adult|Acute Myelogenous Leukemia|High Risk Myelodysplasia
Interventions: DRUG: APTO-253
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amgen 386 for Recurrent Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Amgen 386|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Combined Alcohol and Nitrous Oxide Intake - 15
Status: COMPLETED
Conditions: Opioid-Related Disorders|Substance-Related Disorders
Interventions: DRUG: 30% Nitrous oxide|OTHER: 0.25 g/Kg ethanol|OTHER: 0.5 g/KG ethanol|OTHER: 0 g/Kg ethanol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose:
Clinical trial: Dose-Escalation, Safety and Pharmacokinetic Study of IC14 in Motor Neurone Disease
Status: COMPLETED
Conditions: Motor Neuron Disease|Amyotrophic Lateral Sclerosis
Interventions: BIOLOGICAL: IC14
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin and Combination Chemotherapy in Treating Children and Young Adults With Stage IIB, Stage IIIB, IVA, or IVB Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Ann Arbor Stage IIB Hodgkin Lymphoma|Ann Arbor Stage IIIB Hodgkin Lymphoma|Ann Arbor Stage IVA Hodgkin Lymphoma|Ann Arbor Stage IVB Hodgkin Lymphoma|Childhood Hodgkin Lymphoma|Classic Hodgkin Lymphoma
Interventions: BIOLOGICAL: Bleomycin Sulfate|DRUG: Brentuximab Vedotin|DRUG: Cyclophosphamide|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide|OTHER: Laboratory Biomarker Analysis|DRUG: Methylprednisolone|OTHER: Pharmacological Study|DRUG: Prednisone|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Liposomal Bupivacaine Provide Improved Pain Management for ORIF of Midshaft Clavicle Fractures?
Status: WITHDRAWN
Conditions: Clavicle Fracture
Interventions: DRUG: Liposomal Bupivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrical Stimulation for Attenuating Muscle Atrophy
Status: UNKNOWN
Conditions: COPD
Interventions: DEVICE: NMES new paradigm|DEVICE: NMES conventional|DEVICE: NMES no stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cost-effective Hearing Aid Delivery Models
Status: COMPLETED
Conditions: Presbycusis
Interventions: OTHER: Audiologist-based fitting|OTHER: Over-the-counter fitting|OTHER: Hybrid fitting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: REVIVE: Reducing Exsanguination Via In-Vivo Expandable Foam
Status: RECRUITING
Conditions: Hemorrhagic Shock|Trauma|Exsanguinating Hemorrhage|Shock; Traumatic
Interventions: DEVICE: ResQFoam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Sulfadoxine/Pyrimethamine 500/25 mg Dispersible Tablet
Status: NOT_YET_RECRUITING
Conditions: Fasting
Interventions: DRUG: Sulfadoxine 500 MG / Pyrimethamine 25 MG dispersible tablets.|DRUG: Sulfadoxine 500 MG / Pyrimethamine 25 MG dispersible tablets in SPAQ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RI-001 in Immunosuppressed Respiratory Syncytial Virus (RSV) Infected Patients at Risk of Lower Tract RSV Illness
Status: COMPLETED
Conditions: Upper Respiratory Tract Infection|Lower Respiratory Tract Infection
Interventions: BIOLOGICAL: RI-001|BIOLOGICAL: RI-001|BIOLOGICAL: RI-001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adoptive T Cell Therapy in Patients With Recurrent Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer Recurrent
Interventions: BIOLOGICAL: Tumor Infiltrating Lymphocytes (TIL)|DRUG: Interferon Alfa 2A|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Protective Efficacy of BCG Vaccination Against Controlled Human Malaria Infection
Status: COMPLETED
Conditions: Malaria|Plasmodium Falciparum
Interventions: BIOLOGICAL: BCG vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multicenter Study to Evaluate the Safety and Efficacy of PEP005 Topical Gel When Used to Treat Actinic Keratoses on the Head (Face or Scalp)
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: PEP005 Topical Gel|DRUG: PEP005 Topical Gel|DRUG: PEP005 Topical Gel|DRUG: Vehicle gel|DRUG: PEP005 Topical Gel|DRUG: PEP005 Topical Gel|DRUG: PEP005 Topical Gel|DRUG: Vehicle gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation Combined With Transcatheter Arterial Chemoembolization Versus Radiofrequency Ablation Alone for Recurrent Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|RFA|TACE
Interventions: PROCEDURE: RFA|PROCEDURE: TACE-RFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Impact of Improved Floors on Health
Status: RECRUITING
Conditions: Diarrhoeal Disease|Hookworm Infection|Ascaris Lumbricoides Infection|Trichuris Infection|Tungiasis
Interventions: OTHER: Sealed washable floor plus behaviour change|BEHAVIORAL: Behaviour change intervention|DRUG: Routine deworming|PROCEDURE: treatment for tungiasis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Premedication for Less Invasive Surfactant Administration
Status: RECRUITING
Conditions: Surfactant Deficiency Syndrome Neonatal
Interventions: DRUG: Ketamine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of MyDay™ and 1-DAY ACUVUE® TruEye®
Status: COMPLETED
Conditions: Refractive Error
Interventions: DEVICE: Stenfilcon A contact lenses|DEVICE: Narafilcon A contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of DEXYCU® for the Treatment of Ocular Pain Associated With Cataract Surgery (2)
Status: WITHDRAWN
Conditions: Cataract
Interventions: DRUG: Dexycu|OTHER: Placebo/Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maintaining Oral Health With Bio-products
Status: NOT_YET_RECRUITING
Conditions: Dental Caries|Dental Erosion
Interventions: OTHER: Mouth rinse 1|OTHER: Mouth rinse 2|OTHER: Mouth rinse 3|OTHER: Mouth rinse 4|OTHER: Mouth rinse 5|OTHER: Mouth rinse 6|OTHER: Mouth rinse 7|OTHER: Mouth rinse 8|OTHER: Mouth rinse 9
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: MIRs 04 : Interpectoral Nerve Block With Ropivacaine Versus Placebo Before Breast Cancer Surgery
Status: COMPLETED
Conditions: Malignant Neoplasm of Breast
Interventions: DRUG: Saline|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Planning the Next Steps: Using an Implementation Intention Approach to Increase Daily Walking
Status: COMPLETED
Conditions: Sedentary Lifestyle|Self Efficacy|Control Locus
Interventions: BEHAVIORAL: Control Group|BEHAVIORAL: Implementation Intention Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Fludarabine, Cyclophosphamide, and Rituximab Versus Pentostatin, Cyclophosphamide, and Rituximab in Previously Untreated or Treated B-Cell Chronic Lymphocytic Leukemia Patients
Status: COMPLETED
Conditions: B-Cell Chronic Lymphocytic Leukemia
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Rituximab|DRUG: Pentostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Adherence and Efficiency of a Home-based Training Program on Muscular Strength, Endurance and Qol for Colon Cancer Patients
Status: UNKNOWN
Conditions: Colon Cancer
Interventions: PROCEDURE: Home-based training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Specific PEEK Implants for Immediate Restoration of Temporal Fossa After Maxillary Reconstruction With Temporalis Muscle Flap
Status: COMPLETED
Conditions: Temporal Hollowing
Interventions: PROCEDURE: Temporal PEEK implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Evaluation of Traditional Chinese Medicine JITAI Combined Comprehensive Model Among Heroin Addicts After Detoxification
Status: COMPLETED
Conditions: Heroin Addiction
Interventions: DRUG: JITAI Combined with psychological intervention|DRUG: Methadone|DRUG: Traditional Chinese Medicine JITAI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Individual Early Psychoeducation Program for Schizophrenic Disorders in Inpatients
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DIAGNOSTIC_TEST: PEPITS Programme|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: U0289-402: An Open Label, 8 Week Study to Evaluate the Efficacy and Tolerability of MAXCLARITY II in Subjects With Acne
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: MAXCLARITY II (2.5% BPO) Foam Cleanser|DRUG: MAXCLARITY II (2.5% BPO) Foam Treatment|DRUG: MAXCLARITY II (0.5% Salicylic Acid) Toner Foam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apical External Root Resorption Secondary to Orthodontic Forces and Individual Radicular Stress
Status: RECRUITING
Conditions: Apical Root Resorption
Interventions: PROCEDURE: Maxillary and mandibular Cone Beam Computed Tomography record
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Compare the Efficacy of Cognitive-behavioral Couple Therapy and Lidocaine for Provoked Vestibulodynia
Status: COMPLETED
Conditions: Vulvodynia|Dyspareunia|Vestibulodynia
Interventions: BEHAVIORAL: Cognitive Behavioral Couple Therapy|OTHER: Topical Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: J-Tip® Jet Injection of 1% Buffered Lidocaine or Saline Versus 4% Lidocaine Cream Before Venipuncture or IV Insertion
Status: WITHDRAWN
Conditions: Pain
Interventions: DEVICE: J-Tip jet injector|DEVICE: Jet injection saline|DRUG: lidocaine cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of the Tolerability of Ketorolac Tromethamine Following Intranasal Administration in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Ketorolac tromethamine|DRUG: Ketorolac tromethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Induction Chemotherapy Prior to Radio-immunotherapy in Head and Neck Cancer Stage III/IV - a Methodical Trial
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Docetaxel|DRUG: Cisplatin|DRUG: 5-FU|RADIATION: Radiotherapy|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Abdominal Corset and Core Stabilization Exercises in the Treatment of Postpartum Diastasis Recti Abdominis
Status: COMPLETED
Conditions: Diastasis Recti
Interventions: OTHER: Exercise intervention|OTHER: Exercise intervention by wearing abdominal corset|OTHER: Corset intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Compare the Efficacy of Mepilex and Keramatrix in Second Degree Burn Wounds
Status: WITHDRAWN
Conditions: Skin Burn Degree Second
Interventions: DEVICE: Keramatrix|DEVICE: Mepilex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compliance With Antidepressant Medication in Treatment of Functional Dyspepsia
Status: COMPLETED
Conditions: Dyspepsia|Compliance|Depression
Interventions: DRUG: Omeprazole|DRUG: Flupentixol-Melitracen(psychological and GI) + Omeprazole|DRUG: Flupentixol-Melitracen(psychological) + Omeprazole|DRUG: Flupentixol-Melitracen(without explanation) + Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fruit and Vegetable Biomarker Discovery
Status: RECRUITING
Conditions: Biomarkers
Interventions: OTHER: Aim 1 Meal Challenge 1|OTHER: Aim 1 Meal Challenge 2|OTHER: Aim 1 Meal Challenge 3|OTHER: Aim 2 Typical American Diet|OTHER: Aim 2 Typical American Diet Plus Test Foods|OTHER: Aim 2 Dietary Guidelines for Americans Diet Plus Test Foods
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Atrial Fibrillation Prevention in Post Coronary Artery Bypass Graft Surgery With Cryoablation for Ganglionic Plexi
Status: WITHDRAWN
Conditions: Complication of Coronary Artery Bypass Graft|Atrial Fibrillation
Interventions: PROCEDURE: Two sites cryoablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Applying of Acupressure and Abdominal Massage to Improving Constipation in Stroke Patients.
Status: UNKNOWN
Conditions: Acupressure|Abdominal Massage|Constipation|Stroke Patients
Interventions: OTHER: Acupressure and Abdominal Massage|OTHER: Pressing the Sham points
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 1 Study of PBTZ169
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: PBTZ169 - 40 mg|DRUG: PBTZ169 - 80 mg|DRUG: PBTZ169 - 160 mg|DRUG: PBTZ169 - 320 mg|DRUG: PBTZ169 - 640 mg|DRUG: PBTZ169 - 320 mg (multiple administration)|DRUG: PBTZ169 - 640 mg (multiple administration)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Lebrikizumab (MILR1444A) in Adult Patients With Asthma Who Are Inadequately Controlled on Inhaled Corticosteroids
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: lebrikizumab (MILR1444A)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MR/TRUS Fusion Guided Prostate Biopsy
Status: UNKNOWN
Conditions: Prostate Disease|Elevated Prostate Specific Antigen|Family History of Prostate Cancer|Positive Digital Rectal Exam
Interventions: PROCEDURE: prostate biopsy|PROCEDURE: MR US Fusion Guided Prostate Biopsy|DEVICE: MR/TRUS Fusion Guided Prostate Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Onset and Duration of Forearm Nerve Blockade
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: Lidocaine|DRUG: Bupivacaine|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Complex Endovascular Approach to Treatment of Patients With Aneurysm of Popliteal Artery
Status: UNKNOWN
Conditions: Aneurysm; Popliteal Artery|Limb Ischemia
Interventions: PROCEDURE: Combined endovascular approach (EVAR)|PROCEDURE: Standard optimal therapy (OPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Echocardiographically Guided Versus Standard Ibuprofen Treatment for Patent Ductus Arteriosus
Status: COMPLETED
Conditions: Patent Ductus Arteriosus
Interventions: DRUG: Ibuprofen EchoG|DRUG: Standard ibuprofen treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Blood (UCB) Transplantation in Pediatric Patients With High Risk Leukemia and Myelodysplasia
Status: COMPLETED
Conditions: Leukemia|Myelodysplasia|Acute Lymphocytic Leukemia|Acute Myelogenous Leukemia
Interventions: PROCEDURE: Umbilical Cord Blood Transfusion|DRUG: Fludarabine|DRUG: Busulfan|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chrononutrition and Adolescent Weight Control
Status: UNKNOWN
Conditions: Adolescent Obesity|Diet|Weight Loss|Sleep
Interventions: BEHAVIORAL: Breakfast / Lunch|BEHAVIORAL: Dinner (DIN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypo-METRICS: Hypoglycaemia - Measurement, ThResholds and ImpaCtS
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Hypoglycemia|Hypoglycemia Unawareness
Interventions: OTHER: NO intervention - observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating Aerosol and Intradermal Administration of a Candidate Tuberculosis (TB) Vaccine, MVA85A, as a Way to Increase Immune Response and Avoid Anti-vector Immunity
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: MVA85A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Gain Information How Well Dexpanthenol Derma Cream Helps the Face Skin to Recover After Cosmetic Lasering
Status: COMPLETED
Conditions: Erythema|Skin Recovery
Interventions: DRUG: BAY207543 (Bepanthol)|OTHER: Semisolid vaseline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin and Capecitabine With or Without an Hepatic Arterial Infusion With Floxuridine in Treating Patients Who Are Undergoing Surgery and/or Ablation for Liver Metastases Due to Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: DRUG: capecitabine|DRUG: floxuridine|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Investigate the Pharmacokinetic Drug Interaction Between Udenafil and Dapoxetine
Status: UNKNOWN
Conditions: Healthy Male Subjects
Interventions: DRUG: Dapoxetine|DRUG: Udenafil|DRUG: Udenafil+Dapoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PI Pembro in Combination With Stereotactic Body Radiotherapy for Liver Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Adenocarcinoma|Stage IVA Colorectal Cancer|Stage IVB Colorectal Cancer|Metastatic Carcinoma in the Liver
Interventions: RADIATION: Stereotactic body radiotherapy (SBRT)|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 10E8.4/iMab Bispecific Antibody and VRC07-523LS Monoclonal Antibody in HIV-infected Adults
Status: RECRUITING
Conditions: HIV-1-infection
Interventions: DRUG: ART|DRUG: 10E8.4/iMab|DRUG: VRC07-523LS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT