pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: HIV Pre-exposure Prophylaxis Implementation Study in South Korea
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: tenofovir disoproxil fumarate (TDF) 300mg co-formulated with emtricitabine (FTC 200mg) once daily oral administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Kidney Alone Versus Islet-After-Kidney in Type 1 Diabetic Kidney Transplant Recipient.
Status: RECRUITING
Conditions: type1diabetes|Renal Failure|End Stage Renal Disease
Interventions: OTHER: Pancreatic islet transplantation after kidney transplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of Continuous Glucose Monitors in Publicly-Insured Youth With Type 2 Diabetes - A Pilot and Feasibility Study
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DEVICE: Continuous Glucose Monitor|OTHER: Patient Reported Outcome Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy Study Exploring the Effect of Lu AE58054 as Augmentation Therapy in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Cognition
Interventions: DRUG: Lu AE58054|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Treatments to Maintain Disease Remission in Patients With Wegener's Granulomatosis and Related Vasculitis Syndromes
Status: COMPLETED
Conditions: Vasculitis|Wegener's Granulomatosis
Interventions: DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of Laboratory Changes, Food Intake and Metabolic Profile in Patients With Obesity and Type2 Diabetes Mellitus: Before, During and After Taking AphoelineBrake
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: AphoelineBrake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Innovative Application of Pressure Gradient Measurement in Internal Carotid Stenosis in Patients Undergoing CAS
Status: NOT_YET_RECRUITING
Conditions: Carotid Artery Stenosis|Carotid Artery Stenting|Stroke
Interventions: PROCEDURE: CAS + Intravascular measuring the pressure gradient|PROCEDURE: CAS (standard)|DIAGNOSTIC_TEST: Doppler ultrasonound of cephalic arteries|RADIATION: Angio-CT of the neck and head|OTHER: Otolaryngological examination|OTHER: Psychological examination|OTHER: Neurological examination|DIAGNOSTIC_TEST: MR cerebral perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Antidepressant Medication Plus Directly Observed Therapy for Improving Adherence to Antiretroviral Therapy
Status: COMPLETED
Conditions: HIV Infections|Depression
Interventions: BEHAVIORAL: Directly Observed Therapy (DOT)|DRUG: Fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise to ReGain Stamina and Energy (The EXERGISE Study)
Status: RECRUITING
Conditions: Fatigue|Breast Cancer|Cancer, Therapy-Related
Interventions: BEHAVIORAL: Center-Based Walking Exercise|BEHAVIORAL: Home-Based Walking Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: >The Purpose of This Study Was to Determine Whether Consuming a 100-mL Cup of Coffee is Effective in Preventing or Reducing Postoperative Ileus After Laparotomy of Benign Gynecological Patients
Status: COMPLETED
Conditions: Effects of Coffee Ingestion on Recovery of Bowel Function
Interventions: OTHER: caffeine coffee|OTHER: decaffiene coffee|OTHER: still water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MEDITOXIN® Versus BOTOX® in the Treatment of Post-stroke Spasticity of the Upper Limb Spasticity
Status: COMPLETED
Conditions: Spasticity
Interventions: DRUG: Botulinum toxin type A|DRUG: Botulinum Toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IIb Clinical Trial of Recombinant Novel Coronavirus Pneumonia (COVID-19) Vaccine (Sf9 Cells)
Status: WITHDRAWN
Conditions: COVID-19
Interventions: BIOLOGICAL: Recombinant COVID-19 vaccine (Sf9 cells)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Pharmacokinetic Study of DW6013 (FDC of Linagliptin and Metformin) in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: DW6013
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Dextro-Amphetamin Added to Physiotherapy in Patients After Stroke
Status: TERMINATED
Conditions: Stroke
Interventions: DRUG: Dextro-Amphetamin|OTHER: Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasms
Status: SUSPENDED
Conditions: Acute Biphenotypic Leukemia|Acute Myeloid Leukemia|Mixed Phenotype Acute Leukemia|Myeloid Neoplasm|Relapsed Acute Biphenotypic Leukemia|Relapsed Acute Myeloid Leukemia|Relapsed Mixed Phenotype Acute Leukemia|Relapsed Myeloid Neoplasm|Refractory Acute Biphenotypic Leukemia|Refractory Acute Myeloid Leukemia|Refractory Mixed Phenotype Acute Leukemia|Refractory Myeloid Neoplasm|Recurrent Myeloid Sarcoma
Interventions: DRUG: Cladribine|DRUG: Cytarabine|DRUG: Mitoxantrone|BIOLOGICAL: Recombinant Granulocyte Colony-Stimulating Factor|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Passive Music Intervention for the Reduction of Anxiety in Patients Undergoing Bone Marrow Aspiration and/or Biopsy
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid System Neoplasm
Interventions: PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Music Therapy|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Celiac Disease and Vitamin Status: Evaluation of the Effect of Supplementation With a Probiotic (VIVOMIXX®) in a Cohoort of Celiac Patients
Status: UNKNOWN
Conditions: Celiac Disease
Interventions: DRUG: Probiotic Vivomixx|BEHAVIORAL: Gluten free diet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Protocol Biopsies in High-risk Renal Transplant Recipients
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Transplant Rejection|Kidney Transplant Failure|Kidney Transplant Infection|Kidney Transplant Failure and Rejection
Interventions: PROCEDURE: Percutaneous renal biopsy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics and Safety Study of PT010 and PT003 in Healthy Chinese Adult Subjects
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: PT010 (BGF MDI) 320/14.4/9.6 µg|DRUG: PT010 (BGF MDI) 160/14.4/9.6 µg|DRUG: PT003 (GFF MDI) 14.4/9.6 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Primary Coronary Artery Vascular Lesions With Biolimus Coated Coronary Balloon Dilation Catheter
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: Biolimus Coated Coronary Artery Balloon Dilation Catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Economics of Pulmonary Artery Catheter Use in Patients With Acute Respiratory Distress Syndrome (ARDS)
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Acute Lung Injury|Lung Diseases
Interventions: DEVICE: Pulmonary Artery Catheter|BEHAVIORAL: Protocolized Fluid Management
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigate the Efficacy and Safety of Low-Glu in Patients Newly Diagnosed With Type II Diabetes Mellitus
Status: COMPLETED
Conditions: Type2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Natural Wellness Low-Glu low dose|DIETARY_SUPPLEMENT: Natural Wellness Low-Glu high dose|OTHER: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduction in Consumption of Sweetened Beverages on Weight, Body Composition and Blood Pressure in Young Adults
Status: COMPLETED
Conditions: Obesity and Overweight
Interventions: BEHAVIORAL: Caloric and non-caloric SSBS reduction|BEHAVIORAL: Caloric SSBS reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin Therapy for the Prevention of Atrial Fibrillation (SToP-AF)
Status: TERMINATED
Conditions: Atrial Fibrillation|Inflammation
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Rivaroxaban in Acute Non-neoplastic Portal Vein Thrombosis in HCV
Status: COMPLETED
Conditions: Portal Vein Thrombosis
Interventions: DRUG: Rivaroxaban|OTHER: symptomatic therapy for ascites, abdominal pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of TWK10 Administration on the Effects of Amino Acid Absorption
Status: COMPLETED
Conditions: Amino Acid|Exercise|Probiotic|Body Composition
Interventions: DIETARY_SUPPLEMENT: TWK10|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Demonstrate the Safety of a Novel Powder Formulation of Lactobacilli in Adults
Status: COMPLETED
Conditions: Safety
Interventions: DIETARY_SUPPLEMENT: Lactobacillus Reuteri DSM 17938
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Amisulpride Treatment for BPSD in AD Patients
Status: RECRUITING
Conditions: BPSD|Amisulpride|Olanzapine|Dementia of the Alzheimer Type
Interventions: DRUG: Amisulpride|DRUG: Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cell for Osteonecrosis of the Femoral Head
Status: UNKNOWN
Conditions: Osteochondritis of the Femoral Head
Interventions: BIOLOGICAL: mesenchymal stem cell infusion|BIOLOGICAL: bone marrow mononuclear cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blinatumomab Versus Standard of Care Chemotherapy in Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL)
Status: TERMINATED
Conditions: Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia
Interventions: DRUG: Blinatumomab|DRUG: Standard of Care Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Anlotinib Hydrochloride Combined With Nivolumab in the Treatment of Gastric and Esophageal Cancer
Status: UNKNOWN
Conditions: Gastric Adenocarcinoma|Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Anlotinib Hydrochloride With Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Immunogenicity, Reactogenicity and Safety of Herpes Simplex (gD) Candidate Vaccine With/Without Adjuvant
Status: COMPLETED
Conditions: Prophylaxis Herpes Simplex
Interventions: BIOLOGICAL: Herpes simplex candidate vaccine GSK208141 - non-MPL-containing adjuvant|BIOLOGICAL: Herpes simplex candidate vaccine GSK208141- MPL-containing adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Microcirculatory Function in Type 2 Myocardial Infarction (T2MI)
Status: NOT_YET_RECRUITING
Conditions: Myocardial Infarction|Coronary Microvascular Disease
Interventions: DIAGNOSTIC_TEST: Coronary angiogram with coronary reactivity testing (CRT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of PD-L1 Monoclonal Antibody Combined With Metronomic VEX in Advanced Triple-negative Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Triple Negative Breast Cancer
Interventions: DRUG: Adebrelimab|DRUG: Vinorelbine|DRUG: Cyclophosphamide (tablet)|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting Drug Memories With Methylphenidate
Status: RECRUITING
Conditions: Substance Use Disorder|Cocaine Use Disorder
Interventions: DRUG: Methylphenidate|BEHAVIORAL: Memory reconsolidation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preschool Hearing Screening
Status: RECRUITING
Conditions: Hearing Loss|Hearing Disorders in Children|Hearing Loss, Sensorineural|Hearing Loss, Conductive|Hearing Loss, Unilateral|Hearing Loss, Noise-Induced|Hearing Loss, Mixed|Hearing Loss, Bilateral
Interventions: DIAGNOSTIC_TEST: Otoacoustic Emissions Testing|DIAGNOSTIC_TEST: Pure Tone Audiometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate Safety and PK Profiles of OLX10010 in Healthy Subjects
Status: COMPLETED
Conditions: Cicatrix, Hypertrophic
Interventions: DRUG: OLX10010|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability of TAK-123 After Intravenous Infusion in Japanese Healthy Adult Male Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-123
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diet and Physical Activity Counseling and n3-long Chain (PUFA) Supplementation in Obese Pregnant Women
Status: COMPLETED
Conditions: Obesity|Pregnancy
Interventions: BEHAVIORAL: Lifestyle counseling|DIETARY_SUPPLEMENT: PUFA Supplementation|BEHAVIORAL: Routine diet & PA|DIETARY_SUPPLEMENT: PUFA placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Training for Patients With Eating Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Feeding and Eating Disorders|Anorexia Nervosa|Bulimia Nervosa|Binge-Eating Disorder
Interventions: BEHAVIORAL: Cognitive Remediation Therapy|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Olaparib With Cediranib or AZD6738 for the Treatment of Advanced or Metastatic Germline BRCA Mutated Breast Cancer
Status: RECRUITING
Conditions: Advanced Breast Carcinoma|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8|Germline BRCA1 Gene Mutation|Germline BRCA2 Gene Mutation|HER2/Neu Negative|Metastatic Breast Carcinoma|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage IV Breast Cancer AJCC v8
Interventions: DRUG: Cediranib|DRUG: Ceralasertib|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Designed ePTFE Valved Conduits for Surgical Reconstruction of Right-ventricular Outflow Tract
Status: UNKNOWN
Conditions: Right Ventricular Outflow Tract Absent|Congenital Heart Disease|Pulmonary Valve Disorders
Interventions: DEVICE: new-designed PTFE valved conduits|DEVICE: Bovine jugular vein valved conduits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Vitamin C in Burns >20% Compared to Previous Studies With High Dose Vitamin C
Status: COMPLETED
Conditions: Burns|Ascorbic Acid Deficiency|Burn Shock|Burn Degree Second|Burn Degree Third|Fluid and Electrolyte Imbalance
Interventions: DIETARY_SUPPLEMENT: Vitamin C
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Learning and Executive Function Disorders in Children and Psychosis Risk at Adult-age
Status: COMPLETED
Conditions: Schizophrenia|Learning Disorders|Executive Function Disorders
Interventions: DIAGNOSTIC_TEST: Standardised semi-structured talk|DIAGNOSTIC_TEST: Autistic spectre disorder screening|DIAGNOSTIC_TEST: Anxiety measuring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PNEUMOSTEM for the Prevention and Treatment of Severe BPD in Premature Infants
Status: RECRUITING
Conditions: Severe Bronchopulmonary Dysplasia
Interventions: BIOLOGICAL: PNEUMOSTEM|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Total Compression Time and Rate (Slope) on Incidence of Symptomatic ETD and MEB: A Phase II Prospective Study.
Status: COMPLETED
Conditions: Eustachian Tube Dysfunction|Middle Ear Barotrauma|Middle Ear Disease|Middle Ear; Injury|Pressure Injury|Ear Barotrauma
Interventions: PROCEDURE: Hyperbaric Compression Profile
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Efficacy, Safety and Pharmacokinetics of Orally Administered Tebipenem Pivoxil Hydrobromide (SPR994) Compared to Intravenous Ertapenem in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)
Status: COMPLETED
Conditions: Complicated Urinary Tract Infection|Acute Pyelonephritis
Interventions: DRUG: TBPM-PI-HBr|DRUG: Ertapenem|DRUG: Dummy Infusion|DRUG: Dummy tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuropathic Pain in Patients With Degenerative Lumbar Stenosis
Status: RECRUITING
Conditions: Lumbar Spinal Stenosis|Neuropathic Pain|Spinal Disease
Interventions: DIAGNOSTIC_TEST: DN4 (Douleur Neuropathique 4 Questions) questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Application of Invivo Microscopy Imaging in the Early Diagnosis of Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer|Cervical Precancer
Interventions: PROCEDURE: invivo microscopy group|PROCEDURE: normal group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Using an Intervention Adapted to the Health Literacy Level to Improve Adherence to Medical Recommendations
Status: NOT_YET_RECRUITING
Conditions: Acute Decompensated Heart Failure|Acute Myocardial Infarction
Interventions: OTHER: Interventional educational toolkit specific to low Health Literacy patients, designed with patients and health professionals.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Tetrix on Alleviation of Burning,Itching Associated With Lesions of Contact Dermatitis
Status: COMPLETED
Conditions: Contact Dermatitis
Interventions: DEVICE: Tetrix|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Feasibility of Drug Delivery to Infants During Breastfeeding
Status: COMPLETED
Conditions: Medication Systems|Breast Feeding|Milk, Human|Infant, Newborn
Interventions: DEVICE: Drug delivery during breastfeeding
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Study of Efficacy and Safety of Asciminib in Combination With Imatinib in Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP)
Status: ACTIVE_NOT_RECRUITING
Conditions: CML|Chronic Myelogenous Leukemia|Leukemia, Myeloid Chronic|Hematologic Diseases
Interventions: DRUG: Asciminib add-on|DRUG: Imatinib|DRUG: Nilotinib|DRUG: Asciminib single agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Immunotherapy Combined With Neoadjuvant Chemotherapy in Patients With Locally Advanced HPV (-) Head and Neck Squamous Cell Carcinoma: a Phase II Clinical Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Efficacy and Safety of Immunotherapy Combined With Neoadjuvant Chemotherapy in Patients With Locally Advanced HPV (-) HNSCC
Interventions: DRUG: immunotherapy combined with neoadjuvant chemotherapy in patients with locally advanced HPV (-) head and neck squamous cell carcinoma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Salvage Oligometastasectomy and Radiation Therapy in Recurrent Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Prostate Carcinoma|Metastatic Malignant Neoplasm in the Bone|Metastatic Malignant Neoplasm in the Lymph Nodes|Oligometastasis|Prostate Adenocarcinoma|PSA Failure
Interventions: RADIATION: Hypofractionated Radiation Therapy|RADIATION: Intensity-Modulated Radiation Therapy|PROCEDURE: Metastasectomy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dry Needling Versus Manual Therapy in Patients With Mechanical Neck Pain: A Randomized Control Trial
Status: UNKNOWN
Conditions: Neck Pain
Interventions: OTHER: Dry Needling and Therapeutic Exercises (DNTEx)|OTHER: Manual Therapy and Therapeutic Exercises (MTTEx)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Strategies for Umbilical Cord Care : Dry Cord Care Versus Antiseptic on the Incidence of Omphalitis in Healthy Term Newborn
Status: TERMINATED
Conditions: Omphalitis
Interventions: OTHER: Cord care by simple debridement (soaping, rinsing and drying)|OTHER: Cord care with the use of antiseptics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase I/IIa, First Time in Human, Study of GSK2636771 in Subjects With Advanced Solid Tumors With Phosphatase and Tensin Homolog (PTEN) Deficiency
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: GSK2636771
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Assessment of Single-Dose Odanacatib (MK-0822) in Subjects With Severe Renal Insufficiency (MK-0822-067)
Status: COMPLETED
Conditions: Renal Insufficiency
Interventions: DRUG: MK-0822
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endothelial Dysfunction and Oxidative Stress in Children With Sleep Disordered Breathing.
Status: COMPLETED
Conditions: Obstructive Sleep Apnea of Child
Interventions: PROCEDURE: adenotonsillectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Noninvasive Evaluation of Renal Allograft Fibrosis by MRI
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: OTHER: MRI 1.5T and 3.0T
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: EndoRotor® Endoscopic Mucosal Resection System for the Colon
Status: COMPLETED
Conditions: Polyp of Colon|Endoscopic Mucosal Resection|Recurrent Colon Adenoma
Interventions: DEVICE: EndoRotor Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-DCFPyL PET/CT in High Risk and Recurrent Prostate Cancer
Status: ENROLLING_BY_INVITATION
Conditions: Prostate Neoplasms|Prostatic Cancer|Prostate Cancer|Cancer Of Prostate|Metastatic Prostate Cancer
Interventions: DRUG: 18F-DCFPyL|DRUG: 18F-FDG|DRUG: PSMA-11
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Epidemiological Study on Haemophilia Care and Orthopaedic Status in Developing Countries
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A|Haemophilia A With Inhibitors|Haemophilia B|Haemophilia B With Inhibitors
Interventions: OTHER: No treatment given
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Predictive Factors in Response to Inhaled Corticoids in Chronic Cough
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Budesonide novolizer|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Two-week Study to Compare the Tolerance and Irritation Potential of Two Combination Topical Gel Acne Medications
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Clindamycin and benzoyl peroxide|DRUG: benzoyl peroxide 2.5% and adapalene 0.1% gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Azithromycin in Patients With Bronchiolitis Obliterans
Status: COMPLETED
Conditions: Bronchiolitis Obliterans
Interventions: DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LEO19123 Cream in the Treatment of Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Calcipotriol and LEO80122 (LEO19123 cream)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of PF-06649751 Co-administered With Trimethobenzamide Hydrochloride in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06649751|DRUG: Trimethobenzamide Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Biochemical Brain Changes Correlated With The Antidepressant Effect Of Thyroid Hormones
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Cytomel (liothyronine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Plant Sterols Effect on Previous Statin Therapy
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: OTHER: Ezetimibe + plant sterols|DRUG: Ezetimibe|DIETARY_SUPPLEMENT: Plant sterols
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Strattera and Behavior Therapy on the Home and School Functioning of Children With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: atomoxetine|BEHAVIORAL: Behavior Modification Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Seraprevir in Combination With Sofosbuvir in Chronic Genotype 2,3,6 Hepatitis C Virus Infection Patients
Status: UNKNOWN
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: Seraprevir|DRUG: Sofosbuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison Between Internet Therapy and Group Therapy for Social Phobia - A Trial Using Cognitive Behavioural Therapy
Status: COMPLETED
Conditions: Social Phobia
Interventions: BEHAVIORAL: CBT via the Internet|BEHAVIORAL: CBT group therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Assess The Duration Of Action Of PF-03526299 In Asthmatic Subjects Following Allergen Challenge
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: Active (PF-03526299)|DRUG: Active (PF-03526299)|DRUG: Placebo|DRUG: Active (PF-03526299)|DRUG: Active (PF-03526299)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Evaluation of the Efficacy of the Injection of Botulinum Toxin A vs Scopolamine Patches in the Treatment of Drooling in Children With Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: DRUG: Botox® injection|DRUG: Scopoderm® patches arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of DA-8031 in Male Patients With Premature Ejaculation
Status: UNKNOWN
Conditions: Premature Ejaculation
Interventions: DRUG: DA-8031|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Check The Analgesic And Anti-Inflammatory Effects Of Atorvastatin In Patients Undergoing Abdominal Surgery
Status: UNKNOWN
Conditions: Abdominal Surgery
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Explore the Effect of Dapagliflozin and Stress in Adolescent and Adult Subjects With Type 1 Diabetes (T1D)
Status: TERMINATED
Conditions: Type 1 Diabetes|Diabetic Ketoacidosis
Interventions: DRUG: Dapagliflozin|DRUG: Placebo oral tablet|OTHER: Stress|OTHER: Placebo Stress
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Measurement of Insulin Levels in Cerebral Spinal Fluid (CSF) of Healthy Adults After a Single Intranasal Dose
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: Low dose Regular Insulin|DRUG: High dose Regular insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 1 Trial of Na-ASP-2 Hookworm Vaccine in Previously Infected Brazilian Adults
Status: TERMINATED
Conditions: Hookworm Infection
Interventions: BIOLOGICAL: Na-ASP-2 Hookworm Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Pharmacokinetics and the Effect on Cardiac Repolarization of Odalasvir Administered as a Single Dose Tablet Under Fed Conditions in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Odalasvir 100 mg|DRUG: Placebo|DRUG: Odalasvir 500 mg|DRUG: Odalasvir (Up to maximum 1000 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Dose-Finding Study of E7070 in Combination With Irinotecan
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: E7070 + irinotecan combination|DRUG: Irinotecan + E7070 combination|DRUG: Irinotecan + E7070 combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine+HBIG Versus Vaccine+Placebo for Newborns of HBsAg+ Mothers
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Vaccine+HBIG|DRUG: Vaccine+Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Healthy Volunteer Study Evaluating the the Safety, Tolerability, and Pharmacokinetics of RT234
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: COMBINATION_PRODUCT: Drug: RT234 - vardenafil inhalation powder; Device: RS01 dry powder inhaler (RS01 DPI)|DRUG: Vardenafil Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study of YM155 + Docetaxel in Subjects With Advanced Hormone Refractory Prostate Cancer and Other Solid Tumors
Status: COMPLETED
Conditions: Prostate Cancer|Tumors
Interventions: DRUG: YM 155|DRUG: Docetaxel|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Food Structure on Micronutrient Bioavailability in Human
Status: COMPLETED
Conditions: Food Structure Impact on Micronutrient Bioavailability
Interventions: OTHER: Custard|OTHER: Flan|OTHER: Sponge cake|OTHER: Biscuit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1
Status: RECRUITING
Conditions: HIV-1-infection
Interventions: BIOLOGICAL: ChAdOx1.tHIVconsv1|BIOLOGICAL: ChAdOx1.HIVconsv62|BIOLOGICAL: MVA.tHIVconsv3|BIOLOGICAL: MVA.tHIVconsv4|DRUG: Vesatolimod (VES)|DRUG: GS-5423|DRUG: GS-2872|BIOLOGICAL: MVA.tHIVconsv4|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel, Carboplatin And Low Dose Radiation As Induction Therapy In Locally Advanced Head And Neck Cancer
Status: COMPLETED
Conditions: Squamous Cell Carcinoma
Interventions: RADIATION: Radiotherapy|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroimaging Biomarker for Seizures
Status: UNKNOWN
Conditions: Seizure Disorder|Seizure Disorder, Post Traumatic|Traumatic Brain Injury|Non-Epileptic Seizure|Conversion Disorder|Magnetic Resonance Imaging|Head Injury|Epilepsy
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Seizures|OTHER: Standard Medical Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monocentric, Prospective Study to Assess the Pharmacokinetic Profile of Continuous and Diurnal Subcutaneous Apomorphine Infusion in Patients With Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DRUG: Apomorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Migraine With Aura Inducing Characteristics and Effects on the Cerebral Arteries and Blood Flow by Hypoxia
Status: COMPLETED
Conditions: Headache|Migraine|Aura
Interventions: OTHER: Hypoxia|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pilot Study of Metformin Therapy in Patients With Relapsed Chronic Lymphocytic Leukemia (CLL) and Untreated CLL
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed Chronic Lymphocytic Leukemia
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Budesonide Inhalation Suspension for Acute Asthma in Children
Status: COMPLETED
Conditions: Asthma|Acute Asthma|Reactive Airway Exacerbation
Interventions: DRUG: Budesonide inhalation suspension (0.5 mg/2mL) 2mg, albuterol (5mg/mL) 7.5 or 10mg|DRUG: Prednisolone, prednisone, or methylprednisolone|DRUG: Albuterol, ipratropium bromide|DRUG: Ipratropium bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dye Taping Technique and Temporary Felt Insoles on Pain and Disability in Children With Pes Planus.
Status: COMPLETED
Conditions: Pes Planus
Interventions: OTHER: Low Dye Taping|OTHER: Temporary Felt Insoles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study
Status: RECRUITING
Conditions: Smoking|Smoking, Cigarette|Smoking, Tobacco|Betel Chewer's Mucosa|Tobacco Use|Tobacco Smoking|Alcohol Drinking|Smokeless Tobacco Hyperkeratosis
Interventions: DIAGNOSTIC_TEST: mHealth
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Tolerability of 4 Different Dosage Strengths of BIBW 2992 Tablets to Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBW 2992 MA2 - single rising dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: U-Act-After: An Observational Study on Long-Term Efficacy of Tight Control RoActemra/Actemra (Tocilizumab) and/or Methotrexate in Patients With Early Rheumatoid Arthritis Who Have Participated in the U-Act-Early Study (ML22497)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of HIIT VS Yoga on Level of Pain, Catastrophizing and QoL in Dysmenorrhea
Status: COMPLETED
Conditions: Primary Dysmenorrhea
Interventions: OTHER: High intensity interval training|OTHER: Yoga Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Hybrid Revascularization in Multivessel Coronary Artery Disease
Status: COMPLETED
Conditions: Heart Disease|Myocardial Ischaemia|Coronary Disease|Coronary Artery Disease
Interventions: PROCEDURE: Hybrid revascularization|PROCEDURE: Coronary Artery Bypass Grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polycystic Ovary Syndrome (PCOS): Effect Of Letrozole and Berberine
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Letrozole -Berberine|DRUG: Letrozole|DRUG: Berberine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial for Treatment of Pain and Assessment of Wound Healing in Chronic Venous Leg Ulcers Using Near Infrared Laser Therapy
Status: RECRUITING
Conditions: Venous Leg Ulcer
Interventions: DEVICE: Summus Laser|DEVICE: Summus Laser Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: RCT of an Intersectional Stigma Intervention to Sustain Viral Suppression Among Women Living With Serious Mental Illness and HIV in Botswana
Status: NOT_YET_RECRUITING
Conditions: Hiv|Serious Mental Illness
Interventions: BEHAVIORAL: WMM-based intersectional stigma intervention|BEHAVIORAL: Attention placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Preoperative Docetaxel, Cisplatin and Capecitabine on Serum RUNX3 Hypermethylation Status in Patients With Gastric and Lower Oesophagus Adenocarcinoma
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Docetaxel|DRUG: Cisplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laryseal Pro LMA Versus Ambu Aura Gain LMA in Elective Ophthalmological Surgeries
Status: RECRUITING
Conditions: Laryngeal Masks Comparison
Interventions: DEVICE: LarysealTM Pro|DEVICE: Ambu Aura Gain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Insulin Resistance and Substrate Metabolism After Acute Erythropoietin (EPO) Administration
Status: COMPLETED
Conditions: Insulin Sensitivity
Interventions: DRUG: erythropoietin|DRUG: placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: QuickOpt Chronic Study
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Cardiac Resynchronization Therapy|DEVICE: Optimization using echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diaphragmatic Inspiratory Amplitude as a Prognosticator for Postoperative Pulmonary Complications After Cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pulmonary Complications|Cardiac Surgery
Interventions: DIAGNOSTIC_TEST: DIA measured via Ultrasonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Zinc-AA Supplementation During Pregnancy & Lactation to Assess Effects on ASD Prevalence in Offspring
Status: TERMINATED
Conditions: Autism Spectrum Disorder|Zinc Deficiency|Pregnancy Related
Interventions: DIETARY_SUPPLEMENT: Zn-AA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Keratinized Mucosa on Dental Implants With Mucositis
Status: COMPLETED
Conditions: Peri-Implantitis|Peri-implant Mucositis|Compliance, Patient
Interventions: PROCEDURE: Supportive periodontal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Central Nervous System Uptake of Anti-CD8+ T Cell Minibodies in Multiple Sclerosis and Progressive Multifocal Leukoencephalopathy
Status: RECRUITING
Conditions: Multiple Sclerosis|Progressive Multifocal Leukoencephalopathy
Interventions: DRUG: 89 Zr-Df-crefmirlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Study to Evaluate Nerindocianine as a Surgical Aid in Ureter Delineation During Minimally Invasive Surgery
Status: WITHDRAWN
Conditions: Intraoperative Ureter Injury
Interventions: DRUG: Nerindocianine for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety Study of 4975 in Patients Undergoing Total Hip Replacement
Status: TERMINATED
Conditions: Arthroplasty
Interventions: DRUG: 4975, highly purified capsaicin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT