pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cognitive Skills Training for Homeless Youth
Status: COMPLETED
Conditions: Affective Disorders|Anxiety Disorders|Attention Deficit Disorder|Substance Abuse
Interventions: BEHAVIORAL: Cognitive Remediation|BEHAVIORAL: Computer Skills Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Effect of Metformin in Obese Insulin Resistant Adolescents With Normal Glucose Tolerance
Status: COMPLETED
Conditions: Pediatric Obesity|Insulin Resistance|Hyperinsulinemia
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NPWT vs Primary Closure in SSI Prevention for Emergency Laparotomies for Peritonitis
Status: RECRUITING
Conditions: Peritonitis|Surgical Site Infection|Infections|Wound Infection
Interventions: DEVICE: subcutaneous NPWT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Schroth and Pilates Exercises in Idiopathic Adolescent Scoliosis
Status: ENROLLING_BY_INVITATION
Conditions: Adolescent Idiopathic Scoliosis
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Quinoa on Strength, VO2max and Athletic Performance
Status: RECRUITING
Conditions: Sports Nutrition
Interventions: DIETARY_SUPPLEMENT: cookies that contain 50 grams of quinoa|DIETARY_SUPPLEMENT: cookies without quinoa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cariprazine: Comparison of Slow- and Immediate-release Forms
Status: COMPLETED
Conditions: Pharmacokinetic Profile
Interventions: DRUG: Cariprazine prolonged release tablet A|DRUG: Cariprazine prolonged release tablet B|DRUG: Cariprazine capsule|DRUG: Cariprazine PR tablet A|DRUG: Cariprazine PR tablet B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rectus Sheath Block May Relieve Urethral Catheter Pain
Status: COMPLETED
Conditions: Prostatectomy
Interventions: PROCEDURE: Robotic prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of Acetazolamide in Reducing Paralysis of the Leg in Patients Undergoing Aortic Aneurysm Surgery Surgery
Status: UNKNOWN
Conditions: Thoracic Aneurysm
Interventions: DRUG: Acetazolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobility and Therapeutic Benefits Resulting From Exoskeleton Use in a Clinical Setting (SC140121 Study 1 and 2)
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DEVICE: Indego Exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Two Consecutive Randomized Controlled Trials Using Mobile Phone Applications for Risky Alcohol Use
Status: COMPLETED
Conditions: Binge Drinking|Problematic AOD Use
Interventions: BEHAVIORAL: Promillekoll|BEHAVIORAL: PartyPlanner|BEHAVIORAL: TeleCoach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PENELOPE Observational Study: Prophylaxis and Treatment of Arterial and Venous Thromboembolism
Status: COMPLETED
Conditions: Hematologic Neoplasm|Acute Leukemia|Myelodysplastic Syndrome|Lymphoma|Multiple Myeloma
Interventions: OTHER: Observation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EEG Outcomes From Cognitive Behavioural Therapy for Psychosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Psychotic Disorders|Schizophrenia and Related Disorders
Interventions: BEHAVIORAL: Cognitive Behavioural Therapy for Psychosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Daily Tamsulosin 0.2mg Administration on Renal Function in Patients With Benign Prostatic Hyperplasia
Status: UNKNOWN
Conditions: Chronic Kidney Failure|Prostatic Hyperplasia
Interventions: DRUG: Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Modified Minimally Invasive Surgical Technique With Clindamycin Augmented Platelet-rich Fibrin Versus Platelet-rich Fibrin Alone for Management of Periodontal Intrabony Defects.
Status: UNKNOWN
Conditions: Periodontal Intrabony Defects
Interventions: PROCEDURE: M-MIST + Clindamycin augmented PRF|PROCEDURE: M-MIST + PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bronchodilator Test in Mechanical Ventilated Chronic Obstructive Pulmonary Disease Patients
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: High Flow Nasal Cannula to Prevent Deoxygenation During Induction of General Anesthesia in Cesarean Section
Status: UNKNOWN
Conditions: Hypoxic Brain Injury|Maternal Death
Interventions: OTHER: F Group|OTHER: H Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Stopping Tyrosine Kinase Inhibitors in Affecting Treatment-Free Remission in Patients With Chronic Phase Chronic Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Drug Withdrawn|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Tyrosine Kinase Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hematopoietic Stem Cell Transplantation for Malignant Infantile Osteopetrosis
Status: UNKNOWN
Conditions: Osteopetrosis
Interventions: DRUG: Busulfan, Cyclophosphamide, Thymoglobulin, Fludarabine (Conditioning regimen)|PROCEDURE: Stem Cell Transplantation|DRUG: Cyclosporin, Methotrexate (GVHD prophylaxis)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety of THR-149 in Subjects With Diabetic Macular Edema (DME)
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetic Retinopathy|Diabetic Macular Edema
Interventions: DRUG: THR-149 dose level 1|DRUG: THR-149 dose level 2|DRUG: THR-149 dose level 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of BI 655066/ABBV-066 (Risankizumab) in Patients With Severe Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: placebo|DRUG: risankizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CMP-MYTHiC Trial and Registry - CardioMyoPathy With MYocarditis THerapy With Colchicine
Status: RECRUITING
Conditions: Cardiomyopathies|Myocarditis|Inflammatory Cardiomyopathy|Heart Failure|Ventricular Arrythmia
Interventions: DRUG: Colchicine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Inotersen in Familial Amyloid Polyneuropathy
Status: COMPLETED
Conditions: FAP|Familial Amyloid Polyneuropathy|TTR|Transthyretin|Amyloidosis
Interventions: DRUG: Inotersen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of the rVSVΔG-ZEBOV-GP Ebola Virus Vaccine Candidate in Children Living in Lambaréné, Gabon
Status: COMPLETED
Conditions: Ebola Virus Disease
Interventions: BIOLOGICAL: rVSVΔG-ZEBOV-GP, V920|DIETARY_SUPPLEMENT: Fibre and equilibrate breakfast and lunch|DIAGNOSTIC_TEST: Active detection and treatment of pathogens|COMBINATION_PRODUCT: Fibre and equilibrate breakfast and lunch plus Active detection and treatment of pathogens|BIOLOGICAL: Chikenpox or Varicella vaccine (VARILRIX)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: "Parkinson AKTIV - Non-pharmacological Treatments in an Innovative Parkinson's Network"
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: OTHER: Coordination through the online platform "JamesAKTIV"
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: CMV CTLs in Neonates With CMV Infection
Status: RECRUITING
Conditions: Congenital Cytomegaloviral (CMV) Disease
Interventions: BIOLOGICAL: CMV Cytotoxic T-Lymphocytes|DRUG: Anti-viral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brainstem Dysfunction in COVID-19 Critically Ill Patients: a Prospective Observational Study
Status: COMPLETED
Conditions: COVID-19
Interventions: DIAGNOSTIC_TEST: Brainstem Responses Assessment Sedation Score (BRASS)|DIAGNOSTIC_TEST: Electroencephalogram with EKG lead
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Investigating the Biomarkers in Tumor and Peripheral Blood to Evaluate the Efficacy of Cancer Immunotherapy in Chest Cancer Patients
Status: RECRUITING
Conditions: Lung Cancer|Esophageal Cancer
Interventions: OTHER: In vitro stimulation of Pbmc with tumor antigen nanoparticles
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Addition of Belimumab to B-cell Depletion in Relapsing-remitting Multiple Sclerosis
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: DRUG: Belimumab|DRUG: Short-course Ocrelizumab|DRUG: Continued Ocrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zibotentan and Dapagliflozin Combination, EvAluated in Liver Cirrhosis (ZEAL Study)
Status: RECRUITING
Conditions: Liver Cirrhosis
Interventions: DRUG: Part A: Placebo (matching zibotentan capsule & matching dapagliflozin tablet)|DRUG: Part A: zibotentan (dose B) + dapagliflozin|DRUG: Part B: Placebo (matching zibotentan capsule & matching dapagliflozin tablet)|DRUG: Part B: placebo (matching zibotentan capsule) + dapagliflozin|DRUG: Part B: zibotentan (dose A) + dapagliflozin|DRUG: Part B: zibotentan (dose B) + dapagliflozin|DRUG: Part B: zibotentan (dose C) + dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: IL Ancillary Study of the Therapeutic Hypothermia After Nonshockable Cardiac Arrest Trial.
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: BIOLOGICAL: Inflammatory biomarkers dosage "Hypothermia Arm"|BIOLOGICAL: Inflammatory biomarkers dosage "Normothermia Arm"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab, Yttrium Y 90 Ibritumomab Tiuxetan in Patients W/Relapsed Stage II, III, or IV Follicular NHL
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Methylprednisolone|DRUG: Etoposide|DRUG: Cytarabine|DRUG: Cisplatin|DRUG: Rituximab|DRUG: In-Zevalin|DRUG: Y-Zevalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Step-up to Medium Strength Triple Therapy vs High Strength ICS/LABA in Adult Asthmatics Uncontrolled on Medium Strength ICS/LABA
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma
Interventions: DRUG: Administration via pressurized metered dose inhaler (pMDI)|DRUG: Administration via pressurized metered dose inhaler (pMDI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effects of LSVT-BlG Protocol on Balance, Gait, Fatigue and Quality of Life in Parkinson's Patients
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: OTHER: LSVT-BIG Group via Telerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Short-term Topical Application to Prevent Atopic Dermatitis
Status: COMPLETED
Conditions: Eczema Atopic Dermatitis|Eczema|Eczema, Infantile|Food Allergy
Interventions: OTHER: Skin barrier protection in the first 2 months of life
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Beef in an Optimal Lean Diet (BOLD) Effects on Cardiovascular Disease (CVD) Risk
Status: COMPLETED
Conditions: Hypercholesterolemia|Hypertriglyceridemia
Interventions: DIETARY_SUPPLEMENT: BOLD+ Diet|DIETARY_SUPPLEMENT: BOLD diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Outcome Following Endodontic Treatment Using Traditional Access Versus Conservative Access
Status: UNKNOWN
Conditions: Pulpitis - Irreversible
Interventions: PROCEDURE: Endodontic treatment using traditional access|PROCEDURE: Endodontic treatment using conservative access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identification and Treatment of Hypoxemic Respiratory Failure and ARDS With Protection, Paralysis, and Proning Pathway
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Respiratory Distress Syndrome|Hypoxemic Respiratory Failure|ARDS, Human
Interventions: OTHER: TheraPPP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyanobacteria Allergy in Lake Kineret
Status: UNKNOWN
Conditions: Nasal Stuffiness|Sneezing|Itching
Interventions: PROCEDURE: Skin test with sterile extracts of different cyanobacteria
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Study of Venetoclax Combined With CAG in the Treatment of Refractory/Relapsed Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Ven+CAG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 2-Part Study to Investigate the Dose-Ranging Safety and Pharmacokinetics, Followed by the Efficacy and Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution as an Adjunctive Therapy in Children ≥ 2 Years Old and Young Adults With Dravet Syndrome
Status: COMPLETED
Conditions: Dravet Syndrome
Interventions: DRUG: ZX008 (Fenfluramine Hydrochloride)|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thromboelastography Transfusion Protocol for Pediatric Neuromuscular Scoliosis Surgery
Status: TERMINATED
Conditions: Neuromuscular Scoliosis
Interventions: PROCEDURE: Thromboelastography laboratory testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase III Clinical Study of Azvudine in Hiv-infected Treatment Naive Patients
Status: UNKNOWN
Conditions: HIV-infection/Aids
Interventions: DRUG: FNC|DRUG: 3TC|DRUG: TDF|DRUG: EFV|DRUG: FNC placebo|DRUG: 3TC placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Volume vs Concentration: Quadratus Lumborum Blocks With High Volume/Low Concentration or Low Volume/ High Concentration in Nephrectomies
Status: WITHDRAWN
Conditions: Analgesia|Postoperative Pain|Block
Interventions: DRUG: Ropivacaine 0.5% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cytokine Profile of Conjunctivitis, Performed Through Tears Analysis Among Patients Treated With Dupilumab
Status: UNKNOWN
Conditions: Conjunctival Diseases|Atopic Dermatitis|Side Effect
Interventions: OTHER: Tears sampling|OTHER: Lashes sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety, Tolerability, and Pharmacokinetics of TAK-438 in Healthy Western Male Subjects, Preliminary Food Effect Analysis, and an Ethnic Comparison With Japanese Subjects
Status: COMPLETED
Conditions: Dose Finding Study
Interventions: DRUG: TAK-438|DRUG: TAK-438 Placebo|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Effort-Targeted Pressure Support Ventilation (IT-PSV) Trial
Status: NOT_YET_RECRUITING
Conditions: Critical Care|Acute Hypoxic Respiratory Failure|Ventilator-Induced Lung Injury
Interventions: PROCEDURE: PMI-targeted pressure support setting and adjustment|PROCEDURE: VT/RR-targeted pressure support setting and adjustment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Tourniquet in Total Knee Arthroplasty.
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Atropine or Glycopyrrolate on the Prevention of Bradycardia During Sedation Using Dexmedetomidine in Geriatric Patients Undergoing Total Knee Replacement Under Spinal Anesthesia
Status: COMPLETED
Conditions: Spinal Anesthesia
Interventions: DRUG: Atropine|DRUG: Glycopyrrolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of SHR-1701 With or Without Chemotherapy in Patients With Stage III NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small-Cell Lung Cancer
Interventions: DRUG: SHR-1701+Paclitaxel+carboplatin|DRUG: SHR-1701
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Evaluation of Computerized Olfactory Training Program for Cognitive Decline in Early Alzheimer's Disease
Status: UNKNOWN
Conditions: Mild Cognitive Impairment|Early Alzheimer's Disease|Memory Impairment
Interventions: DRUG: COT|DRUG: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Buspirone Hydrochloride 30mg Tablets, Non-Fasting
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BUSPAR® 30 mg Tablet|DRUG: Buspirone Hydrochloride 30 mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Survival Outcome After Minilaparotomy for the Treatment of Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: PROCEDURE: Colorectal cancer resection via minilaparotomy|PROCEDURE: Laparoscopic colorectal cancer resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Care of Prader-Willi Syndrome : Evaluation of a New Care Program Combining Adapted Physical Activity, Nutrition and Therapeutic Education
Status: RECRUITING
Conditions: Prader-Willi Syndrome|Obesity
Interventions: OTHER: Program combing APA, Nutrition, and Therapeutic Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Rituximab Combined With Prednisone for the Initial Treatment of Chronic Graft Versus Host Disease (cGVHD)
Status: TERMINATED
Conditions: Graft Versus Host Disease
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Enteric-coated Mycophenolate Sodium in Combination With Two Corticosteroid Regimens for the Treatment of Lupus Nephritis Flare
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: DRUG: Mycophenolate sodium|DRUG: Prednisone|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rectal Artery Infusion Chemotherapy Combined With Anti-PD1 Antibody for MSS LARC
Status: RECRUITING
Conditions: Rectal Neoplasms
Interventions: DRUG: Oxaliplatin|PROCEDURE: Rectectomy|DRUG: Capecitabine|DRUG: Anti-PD-1 monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Therapy in Erupted Tooth Extractions
Status: COMPLETED
Conditions: Tooth Extraction|Post-Op Complication|Amoxicillin
Interventions: DRUG: Amoxicillin Clavulanate|DIETARY_SUPPLEMENT: Bifidobacterium longum and Lactoferrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Palliative Care Intervention in Patients With Solid Tumors Participating in Phase I Clinical Trials
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: OTHER: counseling intervention|PROCEDURE: quality-of-life assessment|OTHER: questionnaire administration|OTHER: educational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Low-dose hEparinization in Cerebral Angiography sTudy
Status: COMPLETED
Conditions: Cerebral Angiography|Heparinization
Interventions: DRUG: Heparin|DRUG: Heparin Sodium Injection|OTHER: No heparinization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Thoracic Block Technique on Arterial Blood Gases in Children With Atelectasis on Mechanical Ventilation
Status: COMPLETED
Conditions: Atelectasis|Intensive Care Unit|Children
Interventions: OTHER: Thoracic block technique|OTHER: Designed chest physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study on the Treatment of Osteoporotic Vertebral Fractures Using Vertebral Body Stenting
Status: COMPLETED
Conditions: Vertebral Body Fractures
Interventions: PROCEDURE: Vertebral Body Stenting (VBS)|PROCEDURE: Balloon Kyphoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Intubation Via McGrath Videolaryngoscope on Intraocular Pressure
Status: COMPLETED
Conditions: Intraocular Pressure
Interventions: OTHER: Videolaryngoscope|OTHER: Direct laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Mechanical Dilatation of the Cervix at Elective Caesarean Section on Post-operative Morbidity
Status: NOT_YET_RECRUITING
Conditions: Cesarean Section Complications
Interventions: PROCEDURE: mechanical cervical dilatation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Polydeoxyribonucleotide (PDRN) for Cuff Regeneration
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: DRUG: Polydeoxyribonucleotides|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Feasibility Study of Abraxane and Carboplatin in Epithelial Neoplasms of the Uterus
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: DRUG: Carboplatin AUC|DRUG: Abraxane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Continuous Positive Airway Pressure on Diastolic Function in Patients With Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: CPAP group|DEVICE: sham-CPAP group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Gametocytocidal Efficacy and Safety of Primaquine in Uncomplicated Falciparum Malaria in Uganda
Status: COMPLETED
Conditions: Falciparum Malaria
Interventions: DRUG: Primaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Predictive Value of FDG-TEP During Radiotherapy or Chemo-radiotherapy in Patients With NCSC on the One-year Survival
Status: COMPLETED
Conditions: Lung Cancer|NSCLC
Interventions: PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Study to Evaluate the Safety of Lactobacillus Rhamnosus GG ATCC 53103 (LGG) in Elderly Subjects
Status: COMPLETED
Conditions: Healthy|Elderly
Interventions: BIOLOGICAL: Lactobacillus Rhamnosus GG, ATCC 53103 (LGG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Rectal Insert TAF/EVG Pre-Exposure Prophylaxis (RITE PrEP) Study
Status: RECRUITING
Conditions: Safety Issues
Interventions: DRUG: TAF/EVG rectal insert|DRUG: Matching placebo rectal insert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Somatropin Treatment in Adult Patients on Chronic Dialysis
Status: TERMINATED
Conditions: Chronic Kidney Disease|End-Stage Renal Disease
Interventions: DRUG: somatropin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Brigatinib in Relapsed or Refractory ALK-Positive Anaplastic Large Cell Lymphoma
Status: WITHDRAWN
Conditions: Anaplastic Large Cell Lymphoma, ALK-Positive
Interventions: DRUG: Brigatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Describe the Immunogenicity, Safety, and Tolerability of Neisseria Meningitidis Serogroup B Bivalent Recombinant Lipoprotein 2086 Vaccine (Bivalent rLP2086) in Healthy Subjects Aged ≥24 Months to <10 Years
Status: COMPLETED
Conditions: MENINGOCOCCAL INFECTION
Interventions: BIOLOGICAL: Bivalent rLP2086 Vaccine|BIOLOGICAL: Licensed pediatric hepatits A vaccine|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Metformine and CC Compared With Placebo and CC for Induction Ovulation in PCOS Patients With Insulin Resistant
Status: TERMINATED
Conditions: Polycystic Ovary Syndrome|Hyperandrogenism
Interventions: DRUG: metformine|DRUG: placebo|DRUG: clomiphene citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Masitinib in Patients With Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Masitinib|DRUG: Placebo|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise in Severe Mental Illness. The PsychiActive Project 2.0
Status: UNKNOWN
Conditions: Exercise Therapy|Severe Mental Illness
Interventions: BEHAVIORAL: Exercise training for 12 weeks (wearables)|BEHAVIORAL: Exercise training for 12 weeks (wearables and exergames)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Distal Rectus Femoris Transfer as a Part of Multilevel Surgery in Children With Spastic Diplegia
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: PROCEDURE: Distal rectus femoris transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Trial of a Bio-absorbable Mesh in Challenging Laparoscopic Ventral or Incisional Hernia Repair
Status: COMPLETED
Conditions: Hernia, Ventral|Incisional Hernia
Interventions: DEVICE: Phasix™ ST
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: mSIM: Mobile Simultaneous Aerobic Exercise and Memory Training Intervention for Amnestic Mild Cognitive Impairment
Status: COMPLETED
Conditions: Amnestic Mild Cognitive Impairment
Interventions: BEHAVIORAL: mSIM intervention plus activity monitoring|BEHAVIORAL: Activity monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate add-on Effect of Nisha-Amalaki Tablets Along With Insulin on Glycemic Control in Type 1 Diabetes Patients (RCTNA)
Status: NOT_YET_RECRUITING
Conditions: Type 1 Diabetes
Interventions: DRUG: inj insulin to one group|DRUG: Inj Insulin with Tab Nisha-Amalaki 500 mg twice a day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate AGN-151586 Intramuscular Injections in Adult Participants for Treatment of Glabellar Lines
Status: RECRUITING
Conditions: Glabellar Lines
Interventions: DRUG: AGN-151586|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Functional Recovery Between Laparoscopic and Open Pancreaticoduodenectomy
Status: COMPLETED
Conditions: Functional Recovery|Laparoscopy|Periampullary Cancer
Interventions: PROCEDURE: Laparoscopic group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SPD489 as Adjunctive Treatment in Adults With Negative Symptoms of Schizophrenia
Status: WITHDRAWN
Conditions: Negative Symptoms of Schizophrenia
Interventions: DRUG: SPD489 Low-Dose|DRUG: SPD489 High-Dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Manual Therapy Combined With an Exercise Programme VS Combined Electrotherapy on Football Players With Adductor Tendinopathy
Status: COMPLETED
Conditions: Tenopathy; Lower Limb
Interventions: OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer|Pancreatic Neoplasms|Pancreatic Ductal Adenocarcinoma|Advanced Cancer
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: Mutant KRAS G12V-specific TCR transduced autologous T cells|DRUG: Anti-PD-1 monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Treatment Study of Catatonia Patients
Status: TERMINATED
Conditions: Catatonia
Interventions: DEVICE: Electroconvulsive Treatment (ECT) Right Unilateral|DEVICE: Electroconvulsive Treatment (ECT) - Bilateral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cold Snare Polypectomy Versus Hot Snare Polypectomy for Diminutive and Small Colorectal Polyps
Status: COMPLETED
Conditions: Colonic Polyp|Intestinal Polyp
Interventions: PROCEDURE: cold snare polypectomy|PROCEDURE: hot snare polypectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SEMASEARCH, Retrospective/Prospective Cohort Nested at ATUc/AP2 WEGOVY®
Status: NOT_YET_RECRUITING
Conditions: Obesity|Bariatric Surgery|Binge Eating Disorder|Syndromic Obesity|Sarcopenic Obesity|Iatrogenic Obesity|Psychotropic Drugs
Interventions: OTHER: Data collection|OTHER: Blood sampling|OTHER: Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Cholesterol Lowering Effects of Two Marketed Drugs in Patients With Elevated Cholesterol Levels (0653A-058)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: MK0653A, ezetimibe (+) simvastatin|DRUG: Comparator: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Architectural Parameters in Postmenopausal Women Affected With Primary Hyperparathyroidism
Status: COMPLETED
Conditions: Primary Hyperparathyroidism|Bone Disease
Interventions: DEVICE: HR-pQCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Results of Patients With Glaucoma Undergoing Minimally Invasive Glaucoma Surgery in Conjunction With Cataract Surgery
Status: RECRUITING
Conditions: Glaucoma, Open-Angle|Cataract
Interventions: DEVICE: Vivity IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Biomarker-Based Treatment of Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Previously Untreated Acute Myeloid Leukemia
Interventions: BIOLOGICAL: Samalizumab (BAML-16-001-S1)|BIOLOGICAL: BI 836858 (BAML-16-001-S2)|OTHER: Laboratory Biomarker Analysis|DRUG: Daunorubicin (BAML-16-001-S1)|DRUG: Cytarabine (BAML-16-001-S1)|DRUG: Azacitidine (BAML-16-001-S2)|DRUG: AG-221 (BAML-16-001-S3)|DRUG: Azacitidine (BAML-16-001-S3)|DRUG: Entospletinib (BAML-16-001-S4)|DRUG: Azacitidine (BAML-16-001-S4)|DRUG: Entospletinib (BAML-16-001-S5)|DRUG: Decitabine (BAML-16-001-S5)|DRUG: Entospletinib (BAML-16-001-S6)|DRUG: Daunorubicin (BAML-16-001-S6)|DRUG: Cytarabine (BAML-16-001-S6)|DRUG: Pevonedistat (BAML-16-001-S9)|DRUG: Azacitidine (BAML-16-001-S9)|DRUG: AG-120 (BAML-16-001-S16)|DRUG: Azacitidine (BAML-16-001-S16)|DRUG: Gilteritinib (BAML-16-001-S8 Group 1)|DRUG: Decitabine (BAML-16-001-S8 Group 1)|DRUG: AZD5153 (BAML-16-001-S10)|DRUG: Venetoclax (BAML-16-001-S10)|DRUG: TP-0903 (BAML-16-001-S14)|DRUG: Decitabine (BAML-16-001-S14)|DRUG: Decitabine (BAML-16-001-S8 Group 2)|DRUG: Venetoclax (BAML-16-001-S8 Group 2)|DRUG: AZD5991 (BAML-16-001-S18)|DRUG: Azacitidine (BAML-16-001-S18)|DRUG: SNDX-5613 (BAML-16-001-S17)|DRUG: Azacitidine (BAML-16-001-S17)|DRUG: Venetoclax (BAML-16-001-S17)|DRUG: Gilteritinib (BAML-16-001-S8 Group 2)|DRUG: Venetoclax (BAML-16-001-S12 Arm A)|DRUG: Azacitidine (BAML-16-001-S12 Arm A)|DRUG: Venetoclax (BAML-16-001-S12 Arm B)|DRUG: Azacitidine (BAML-16-001-S12 Arm B)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computerized Decision Support System Linked to Electronic Health Records to Improve Patient Care in a General Hospital
Status: COMPLETED
Conditions: Physician's Role
Interventions: OTHER: Medilogy Decision Support System (MediDSS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of LNK01001 Capsule in Subjects With Active Rheumatoid Arthritis
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: LNK01001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Temporomandibular Bioviscosuplementation (Platelet-Rich Plasma Combined With Hyaluronic Acid) After Double-Puncture Arthrocentesis: a Randomized Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Temporomandibular Joint Disorders
Interventions: PROCEDURE: Double-puncture TMJ arthrocentesis under local anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IIIB Study Evaluating the Effects of Atazanavir Powder With Ritonavir in HIV-infected Pediatric Patients
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Atazanavir Sulphate|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lutein Absorption in Healthy Adults
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: OTHER: Study product containing lutein|OTHER: Study product containing lutein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tai Chi Intervention for Geriatric Pain Syndrome
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain|Falls
Interventions: BEHAVIORAL: Light physical exercise|BEHAVIORAL: Tai Chi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Montelukast for Children With Chronic Otitis Media With Effusion (COME): A Double-blind, Placebo-controlled Study
Status: UNKNOWN
Conditions: Chronic Otitis Media With Effusion|Conductive Hearing Loss
Interventions: DRUG: Montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neuroprotective/Neurotrophic Effect of Lexapro® in Patients With Posttraumatic Stress Disorder
Status: UNKNOWN
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: escitalopram (lexapro)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Steroids on Skin Outcomes in Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DRUG: Prednisone|DRUG: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Influence of Bone Allograft Particle Sizes on the Quantity and Quality of New Bone Formation in Grafted Extraction Sockets and Edentulous Ridges
Status: COMPLETED
Conditions: Alveolar Ridge Augmentation|Alveolar Ridge Preservation
Interventions: DEVICE: Socket Grafting with small particle allograft|DEVICE: Socket Grafting with large particle allograft|DEVICE: Lateral ridge augmentation with small particle allograft|DEVICE: Lateral ridge augmentation with large particle allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC)
Status: UNKNOWN
Conditions: Peritoneum Cancer|Peritoneum Neoplasm|Pleural Cancer|Pleural Effusion|Pleural Mesothelioma|Ovarian Cancer|Gastric Cancer|Appendix Cancer|Pseudomyxoma Peritonei|Colorectal Cancer|Pancreas Cancer|Gallbladder Cancer|Ascites|CUP|Chemotherapeutic Toxicity
Interventions: COMBINATION_PRODUCT: PIPAC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Camrelizumab Combined With Apatinib ,Carboplatin and Etoposide in Participants With ES-SCLC
Status: UNKNOWN
Conditions: Small-cell Lung Cancer
Interventions: DRUG: camrelizumab|DRUG: Apatinib Mesylate|DRUG: Carboplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: OMNYPULSE™ Catheter with the TRUPULSE Generator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab in Neoadjuvant Treatment of Non-Resectable Colorectal Liver Metastases (CELIM)
Status: COMPLETED
Conditions: Colorectal Cancer|Liver Metastases
Interventions: DRUG: Cetuximab|PROCEDURE: Liver resection|DRUG: Cetuximab and FOLFIRI|DRUG: Cetuximab and FOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Platelet Rich Plasma After Arthroscopic Debridement for Triangular Fibrocartilage Complex Tears
Status: TERMINATED
Conditions: Arthroscopic Surgery|Triangular Fibrocartilage Complex Injury
Interventions: DEVICE: Platelet-rich Plasma (PRP)|OTHER: Standard Arthroscopic Debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Interferon Alfa in Treating Patients With Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: recombinant interferon alfa|BIOLOGICAL: sargramostim|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: etoposide|DRUG: methotrexate|DRUG: mitoxantrone hydrochloride|PROCEDURE: bone marrow ablation with stem cell support|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab for Advanced Hepatocellular Carcinoma in Patients With Active Chronic Hepatitis B Virus Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Immunogenicity of 'IL-YANG Flu Vaccine Quadrivalent Inj' in Healthy Korean Adults
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: IL-YANG Flu Vaccine QIV 0.5mL|BIOLOGICAL: IL-YANG Flu Vaccine TIV 0.5mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Olive Leaves as Hypoglycemic Agents in Diabetic Subjects
Status: COMPLETED
Conditions: Diabetes
Interventions: DIETARY_SUPPLEMENT: olive leaf extract|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dialysate Temperature on Haemodynamic Stability and Haemodialysis Efficiency
Status: COMPLETED
Conditions: Acute Renal Failure|Chronic Renal Failure
Interventions: PROCEDURE: Haemodialysis with different dialysate temperatures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Longitudinal COVID-19 Antibody Testing in Indiana University Undergraduate Students
Status: COMPLETED
Conditions: SARS-CoV-2|Serology|Students
Interventions: BEHAVIORAL: Immediate vs. delayed provision of antibody test results
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: AMG 757 and AMG 404 in Subjects With Small Cell Lung Cancer (SCLC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Tarlatamab|DRUG: AMG 404
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT