pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Sleep Treatment Education Program for Young Adult Cancer Survivors (STEP-YA)
Status: RECRUITING
Conditions: Insomnia|Insomnia Due to Medical Condition|Cancer
Interventions: BEHAVIORAL: STEP-YA with Coaching|BEHAVIORAL: STEP-YA without Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postsurgical Bupivacaine Extended-release Liposome Injection for Open-reduction Internal Distal Radius Fixation.
Status: TERMINATED
Conditions: Distal Radius Fracture
Interventions: DRUG: Exparel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Evaluating the Safety of a New Catheter for Urinary Intermittent Catheterization in Self Catheterized Patients
Status: COMPLETED
Conditions: Intermittent Urethral Catheterization
Interventions: DEVICE: Actreen Hydrolite Cath
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combining VNS With PT Interventions for Individuals With PD
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: taVNS|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rosuvastatin Evaluation as a Tuberculosis Treatment Adjunct
Status: UNKNOWN
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: Rosuvastatin 10mg|DRUG: Rifampicin|DRUG: Isoniazid|DRUG: Pyrazinamide|DRUG: Ethambutol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plant Versus Animal Dietary Protein and the Effect on Proteinuria
Status: UNKNOWN
Conditions: Kidney Insufficiency|Diabetes Mellitus|Diabetes Mellitus, Type 2|Diabetes Mellitus, Type 1|Diabetes Complications|Hypertension|Glomerulonephritis|Kidney Diseases|Kidney Disease, Chronic
Interventions: OTHER: High Animal Protein Diet (HAPD)|OTHER: High Plant Protein Diet (HPPD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Zanubrutinib Given in Combination With Bendamustine and Rituximab in (Elderly or TP53 Alterations or Chemotherapy Intolerance) Patients With Newly Diagnosed Mantle Cell Lymphoma
Status: RECRUITING
Conditions: Lymphoma, Mantle-Cell
Interventions: DRUG: Zanubrutinib|DRUG: Rituximab|DRUG: Bendamustin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of a Novel Artificial Intelligence Assisted Platform to Assess Optimal Dosing and Treatment Strategy of Erythropoiesis-stimulating Agents (ESA) in Hemodialysis Patients
Status: UNKNOWN
Conditions: End Stage Renal Disease on Dialysis
Interventions: DEVICE: novel artificial intelligence assisted platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Transcranial Magnetic Stimulation (TMS) Treatment for Alcohol Use Disorder
Status: UNKNOWN
Conditions: Alcoholism
Interventions: DEVICE: Transcranial Magnetic Stimulation (rTMS)|DEVICE: Sham (SS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Meditation With Virtual Reality for Cancer Pain Relief in the Pain Therapy and Palliative Care Service
Status: NOT_YET_RECRUITING
Conditions: Cancer Pain|Quality of Life|Palliative Medicine
Interventions: DEVICE: Case group|BEHAVIORAL: Active control group|BEHAVIORAL: Passive control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Jing Si Herbal Tea Liquid Packets on Chronic Pharyngolaryngitis
Status: RECRUITING
Conditions: Chronic Pharyngitis
Interventions: OTHER: control group|OTHER: Jing Si herbal tea liquid packets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety Study of Oral BG00012 With Active Reference in Relapsing-Remitting Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: BG00012|DRUG: Placebo|DRUG: Glatiramer Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intranasal Dexmedetomidine Sedation at Dose of 2 mcg/kg Versus 4 mcg/kg in Children Undergoing MRI
Status: COMPLETED
Conditions: Anesthesia|Deep Sedation|Magnetic Resonance Imaging|Pediatric ALL
Interventions: DRUG: Intranasal dexmedetomidine at dose of 2 mcg/kg and 4 mcg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Escalation Prime/Boost Therapeutic Vaccination Study Of 2 Chimp Adenoviral Vectors in Adults With Chronic HBV On Nucleos(t)Ide Therapy
Status: RECRUITING
Conditions: Chronic Hepatitis B
Interventions: BIOLOGICAL: VRON-0200-AdC6|BIOLOGICAL: VRON-0200-AdC7
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: XENOX - Evaluation of the Efficacy of Xaliproden in Reducing the Neurotoxicity of the Oxaliplatin + 5-FU/LV Chemotherapy
Status: COMPLETED
Conditions: Metastases|Colorectal Neoplasms|Colorectal Carcinoma
Interventions: DRUG: SR57746A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Dexmedetomidine Versus Fentanyl Following Pressure Equalization Tube Placement
Status: COMPLETED
Conditions: Chronic Otitis Media
Interventions: DRUG: Dexmedetomidine|DRUG: Fentanyl|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-comparative Trial Following Participants Implanted Bilaterally With Mini WELL Toric Ready Intraocular Lens for 6 Months After the Second Eye Implant (FUSION)
Status: COMPLETED
Conditions: Bilateral Cataract|Astigmatism
Interventions: DEVICE: Mini WELL Toric Ready intraocular lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ICU Predictive Score of WEaning Success in Patients At Risk of Extubation Failure
Status: RECRUITING
Conditions: Mechanical Ventilator Weaning|Predictive Value of Tests|Ventilator Weaning|Airway Extubation|Care Unit, Intensive|Critical Care|Area Under Curve|Sensitivity and Specificity|Logistic Models|Prospective Studies|Echocardiography, Transthoracic|Ultrasonography|Biomarkers / Blood
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Using Prebiotics to Improve Gut Microbiome Diversity After Autologous Stem Cell Transplantation
Status: RECRUITING
Conditions: Multiple Myeloma|Lymphoma
Interventions: DIETARY_SUPPLEMENT: Resistant Starch|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose-ranging Study of Oral COL-144 in Acute Migraine Treatment
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: Lasmiditan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Testing of a TTDSS for Cancer Patients
Status: UNKNOWN
Conditions: Treatment Side Effects
Interventions: DEVICE: the Mandarin Version of the electronic patient self-Reporting of Adverse-events (eRAPID-MV)|DEVICE: the telephone triage decision support system (TTDSS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Evaluate Safety and Tolerability of Single Ascending Doses of Multiple Formulations of PF-06650833 in Healthy Subjects Under Fasted and Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06650833|DRUG: Placebo|DRUG: PF-06650833|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Employment and Arthritis: Making it Work
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Ankylosing Spondylitis|Lupus Erythematosus, Systemic|Psoriatic Arthritis|Other Connective Tissue Diseases|Spondylarthropathy
Interventions: BEHAVIORAL: Employment and Arthritis: Making it Work
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Stress, Inflammation and Immune Response Pilot Study- Aim 3
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus|Inflammation
Interventions: BEHAVIORAL: App based mindfulness program (ABMP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Alcohol Cessation Among Head and Neck Cancer Survivors
Status: ENROLLING_BY_INVITATION
Conditions: Head and Neck Cancer|Alcohol Use, Unspecified
Interventions: BEHAVIORAL: Alcohol Cessation Text Messages|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Selective Retinal Pigment Epithelium Laser Therapy for Macular Disease of the Retina
Status: TERMINATED
Conditions: Macular Edema|Central Serous Chorioretinopathy|Retinal Vein Occlusion|Age-related Macular Degeneration|Retinal Neovascularization
Interventions: DEVICE: Selective retinal pigment epithelium laser therapy using the R:GEN Laser System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post CVA Persistent Hypertension Caring
Status: UNKNOWN
Conditions: Post CVA Hypertension
Interventions: PROCEDURE: Auto-measure of the tension by an autotensiometer|PROCEDURE: Auto-measure of the tension by an autotensiometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Azithromycin Therapy in Improvement of Symptoms and Lung Function in Patients With Bronchiolitis Obliterans After Bone Marrow Transplantation
Status: COMPLETED
Conditions: Bronchiolitis Obliterans|Bone Marrow Transplantation
Interventions: DRUG: Azithromycin|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin Prevention of (GVHD) After Unrelated Allogeneic Stem Cell Transplantation
Status: COMPLETED
Conditions: Leukemia, Acute Myeloid|Leukemia, Lymphoblastic,Acute|Myelodysplastic Syndromes
Interventions: DRUG: brentuximab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motivational Interviewing Effect on Reducing Cardiovascular Disease Risk Factors
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Diseases|Motivation|Nurse's Role|Risk Reduction
Interventions: OTHER: motivational interviewing based training program|OTHER: Routine practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Ozurdex as Adjunct to Avastin Compared to Avastin Alone in Treatment of Patients With Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Bevacizumab|DRUG: dexamethasone intravitreal implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vactosertib in Combination With Pembrolizumab in Metastatic Colorectal or Gastric Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Cancer|Gastric Cancer|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: TEW-7197
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted Intervention for Patient Centered Outcome in Patients With Idiopathic Pulmonary Fibrosis
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: OTHER: Multi-Disciplinary Patient Centered Rehab and Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pembrolizumab for the Treatment of Cervical Intraepithelial Neoplasia
Status: RECRUITING
Conditions: Cervical Intraepithelial Neoplasia|Cervical Squamous Cell Carcinoma In Situ|Cervical Squamous Intraepithelial Neoplasia 2
Interventions: BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Jejunal Placement of Enteral Feeding Tubes
Status: COMPLETED
Conditions: Critical Illness|Tube Feeding
Interventions: DEVICE: Electromagnetic imaging for jejunal tube placement (CORTRAK)|DEVICE: Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Caregiver Self-Management Needs Through Skill-Building
Status: COMPLETED
Conditions: Family Caregivers|Stroke
Interventions: BEHAVIORAL: Telephone Assessment and Skill-Building Kit (TASK III) Group|BEHAVIORAL: Information Support and Referral (ISR) Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Horyzons: Implementation in Clinical Practice
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorders|Unspecified Schizophrenia Spectrum and Other Psychotic Disorder
Interventions: DEVICE: Horyzons USA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addition of Loncastuximab Tesirine to Acalbrutinib , Chronic Lymphocytic Leukemia
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Loncastuximab Tesirine and Acalabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Utility of Endothelial Dysfunction in PAD
Status: TERMINATED
Conditions: Peripheral Arterial Disease
Interventions: DRUG: atorvastatin|DRUG: ascorbic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Association of Genetic Polymorphisms With Docetaxel-based Chemotherapy Toxicities in Chinese Solid Tumor Patients
Status: UNKNOWN
Conditions: Solid Tumors|Docetaxel|Drug-Related Side Effects and Adverse Reactions|Pharmacogenetics|Pharmacokinetics
Interventions: GENETIC: detection of genotype
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Ischaemic-reperfusion on the Endogenous Fibrinolysis in Man
Status: COMPLETED
Conditions: Ischaemic Heart Diseases
Interventions: PROCEDURE: Forearm vascular study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of High Voltage Pulsed Current (HVPC) and Low Level Laser Therapy (LLLT) on Wound Healing in Diabetic Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: High voltage pulsed current|DEVICE: Low level laser|OTHER: Standard nursing care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Versus Deferred Androgen Deprivation Therapy,Goserelin for Recurrent Prostate Cancer After Radical Radiotherapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Goserelin Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does the Use of Bispectral Index Reduce the Oxidative Stress in Endoscopic Retrograde Cholangiopancreatography?
Status: COMPLETED
Conditions: Oxidative Stress
Interventions: DEVICE: Bispectral Index Monitorisation (BIS)|OTHER: Ramsey Sedation Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pharmacokinetic Effect of Evotaz/Microgynon Co-administration
Status: TERMINATED
Conditions: HIV
Interventions: DRUG: Microgynon 30®|DRUG: Evotaz®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pharmacist Intervention to Reduce Post-Hospitalization Utilization
Status: ACTIVE_NOT_RECRUITING
Conditions: Nonadherence, Patient|Polypharmacy|Readmission
Interventions: BEHAVIORAL: Pharmacist-led Hospital Discharge Care Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Open-Label Study of Oral CEP-701 (Lestaurtinib) in Patients With Polycythemia Vera or Essential Thrombocytosis
Status: COMPLETED
Conditions: Polycythemia Vera|Essential Thrombocytosis
Interventions: DRUG: lestaurtinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasonic Neuromodulation for Treatment of Cognitive Impairment
Status: RECRUITING
Conditions: Alzheimer Disease|Dementia|Cognitive Impairment
Interventions: DEVICE: Diadem prototype
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CBD for Sleep in People With HIV
Status: WITHDRAWN
Conditions: Sleep Disturbance
Interventions: DRUG: Cannabidiol oral solution|DRUG: Inert sesame seed oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Application and Validation of Triple Drug Response Surface Models on Density Spectral Array in Clinical Anesthesia
Status: UNKNOWN
Conditions: Anesthesia|Drug Interaction|Anesthesia; Functional
Interventions: DEVICE: Bispectral index (BIS) or Patient State Index (PSI)|DRUG: Propofol|DRUG: Alfentanil|DRUG: Dexmedetomidine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Immune Response During SARS-CoV-2 Infection - (COVID-19)
Status: COMPLETED
Conditions: New Coronavirus Disease (COVID-19), Infection With SARS-CoV-2
Interventions: OTHER: blood sampling|OTHER: additional blood tubes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of the Safety, Tolerability, Pharmacokinetics and Food Effects of VV119 Capsules in Chinese Healthy Volunteers
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: VV119(SAD)|DRUG: VV119 Placebo(SAD)|DRUG: VV119(FE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Obatoclax Mesylate (GX15-070MS)in Combination With Docetaxel for the Treatment of Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Obatoclax mesylate 250 ml|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Clinical Trial of PXD101 in Patients With Recurrent or Refractory Cutaneous and Peripheral T-Cell Lymphomas
Status: TERMINATED
Conditions: Cutaneous T-Cell Lymphoma|Peripheral T-Cell Lymphoma|Non-Hodgkin's Lymphoma
Interventions: DRUG: belinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine 10% Spray Reduces Pain During Intrauterine Device Insertion
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Lidocaine Spray|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect Of Low Level Laser Therapy on the Rate of En- Masse Retraction: RCT
Status: COMPLETED
Conditions: Bimaxillary Protrusion
Interventions: PROCEDURE: En- masse retraction and LLLT|PROCEDURE: En- masse retraction without LLLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SMART GOALS for Youth With Prediabetes
Status: RECRUITING
Conditions: PreDiabetes|Adolescent Obesity|Behavior, Health|Nutritional and Metabolic Diseases|Diet Habit|Lifestyle Risk Reduction
Interventions: BEHAVIORAL: SMART GOALS Setting Tool/ Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tofacitinib for Treatment of Moderate COVID-19
Status: TERMINATED
Conditions: COVID-19 Pneumonia
Interventions: DRUG: Tofacitinib 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Navigated αTMS in Treatment-resistant Schizophrenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DEVICE: navigated Transcranial Magnetic Stimulation|DEVICE: navigated Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Among Three Different Video Scope Guided Nasotracheal Intubation.
Status: NOT_YET_RECRUITING
Conditions: Intubation, Intratracheal|Airway Management
Interventions: BEHAVIORAL: video laryngoscope guided nasotracheal intubation|BEHAVIORAL: video rigid laryngoscope guided nasotracheal intubation|BEHAVIORAL: video fiberoptic scope guided nasotracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Ophthalmic Solution in Healthy, Normal Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers Eligible for Study; Drug Being Developed for Allergic Conjunctivitis
Interventions: DRUG: R89674 (generic name not yet established)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Investigate the Effect of Different Doses of Lesogaberan (AZD3355) as add-on to PPI in GERD Patients With Partial Response to PPI
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease|Heartburn|Regurgitation
Interventions: DRUG: lesogaberan (AZD3355)|DRUG: lesogaberan (AZD3355)|DRUG: lesogaberan (AZD3355)|DRUG: lesogaberan (AZD3355)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of Elezanumab When Added to Standard of Care in Relapsing Forms of Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis (MS)
Interventions: DRUG: elezanumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cardiac Hemodynamic Modifications During Temporary Left Atrial Appendage Occlusion
Status: COMPLETED
Conditions: Cardiac Surgery
Interventions: DEVICE: Transesophageal echocardiogram|DEVICE: Thermistor-tipped catheter|DEVICE: Pressure/volume catheter|DEVICE: Transthoracic echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Augmented Reality Assisted Lung Nodule Localization: a Multicentered, Prospective, Randomly Controlled, Non-inferiority Trial
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer
Interventions: DEVICE: Augmented reality guided localization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Transcranial Direct Current Stimulation (tDCS) Combined With Aerobic Exercise in Chronic Nonspecific Low Back Pain (LBP)
Status: RECRUITING
Conditions: Low Back Pain|Chronic Low-back Pain
Interventions: OTHER: real tDCS and aerobic exercise|OTHER: sham tDCS and aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The PREVENTS Trial: The Preventing Recurrent Events in Veterans Navigating Transient Ischemic Attack (TIA) or Stroke Trial
Status: COMPLETED
Conditions: Stroke|Transient Ischemic Attack
Interventions: BEHAVIORAL: tailored intervention|BEHAVIORAL: attention placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Totally Extraperitoneal Repair of Groin Hernia in Liver Transplanted Patients
Status: COMPLETED
Conditions: Liver Transplant Disorder|Liver Cirrhosis|Groin Hernia
Interventions: PROCEDURE: Totally Extraperitoneal Groin Hernia Repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase III Confirmatory Study of K-877 Extended Release Tablet
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DRUG: K-877 ER 0.2 mg/day (once daily)|DRUG: K-877 ER 0.4 mg/day (once daily)|DRUG: K-877 IR 0.2 mg/day (twice daily)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Swaddling to Improve Neurodevelopment for Preterm Babies
Status: NOT_YET_RECRUITING
Conditions: Preterm Birth|Neurodevelopmental Disorders
Interventions: OTHER: Novel Swaddle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I/Ib Safety and Efficacy Study of the PI3K-delta Inhibitor TGR-1202 and Ibrutinib in Patients With CLL or MCL
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma|Mantle Cell Lymphoma
Interventions: DRUG: TGR-1202|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of the Monoclonal Antibody CT-011 in Patients With Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Primary Hepatocellular Carcinoma
Interventions: DRUG: CT-011
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ixazomib and Ibrutinib in Relapsed/Refractory Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Mantle-Cell Lymphoma
Interventions: DRUG: Ixazomib|DRUG: Ixazomib|DRUG: Ibrutinib|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Cognitive Function Study of EVP-6124 in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Central Nervous System Diseases|Cognition
Interventions: DRUG: EVP-6124|DRUG: Placebo|DRUG: EVP-6124
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Efficacy, Safety, and Tolerability of Cariprazine Relative to Placebo in Participants With Bipolar I Depression
Status: COMPLETED
Conditions: Bipolar Disorder|Depression
Interventions: DRUG: Cariprazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Type That Faster Reduces Postprandial Glycemia.
Status: ENROLLING_BY_INVITATION
Conditions: Glucose, High Blood|Exercise-Induced Hyperinsulinism
Interventions: BEHAVIORAL: TYPE OF EXERCISE (OR REST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy Of Eptifibatide Compared To Abciximab In Primary Percutaneous Coronary Intervention (PCI) For Acute ST Elevation Myocardial Infarction (STEMI)
Status: COMPLETED
Conditions: Infarction, Myocardial
Interventions: DRUG: Abciximab|DRUG: Eptifibatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Sham Controlled Study of the Effects of Ultrasonic Shockwaves as a Treatment for Chronic Pelvic Pain
Status: WITHDRAWN
Conditions: Chronic Pelvic Pain
Interventions: DEVICE: Low intensity extracorporeal shockwave therapy|DEVICE: Sham low intensity extracorporeal shockwave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Efficacy and Safety of JCAR017 to Standard of Care in Adult Subjects With High-risk, Transplant-eligible Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphomas
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: Standard of Care|GENETIC: JCAR017
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Computerized Cognitive Remediation Therapy for Chronic Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: OTHER: Cognitive Remediation Therapy|DRUG: Clozapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Characteristics of Non-targeted Metabolomics and EEG of Delayed Neurocognitive Recovery in Elderly Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Delayed Neurocognitive Recovery
Interventions: OTHER: Collecting clinical data, EGG，arterial blood gas data and venous blood sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrasonographic Insulin Versus Dexamethasone Injection With Local Anestheticss in Diabetic Patients With Mild to Moderate Median Nerve Entrapement Neuropathy .
Status: UNKNOWN
Conditions: Pain, Neuropathic
Interventions: DRUG: insulin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Somofilcon A Daily Disposable Test Contact Lens and Somofilcon A Daily Disposable Control Contact Lens
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: somofilcon A 1 day test lens|DEVICE: somofilcon A 1 day control lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of the Implant-prosthetic Connection in the Marginal Bone Loss and Bacterial Leakage
Status: UNKNOWN
Conditions: Dental Implant|Bone Loss|Bacterial Infections
Interventions: OTHER: Dental Implant Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Bimatoprost Sustained-Release (SR) in Patients With Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: Bimatoprost SR|OTHER: Sham: Applicator Without Needle|DRUG: Active Comparator: Timolol 0.5%|DRUG: Timolol Vehicle (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Efficacy and Safety of Nilotinib 300mg Twice Daily in Patients With Philadelphia Positive Chronic Myeloid Leukaemia (CML) in Chronic Phase Who Are Intolerant to Prior Tyrosine Kinase Inhibitors.
Status: TERMINATED
Conditions: Philidelphia Positive Chronic Myeloid Leukaemia
Interventions: DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Peripheral Nerve Block Versus Forearm Bier's Block in Patients Undergoing Carpal Tunnel Release
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|Anesthesia, Local
Interventions: PROCEDURE: regional anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gastric Acid Suppression and Probiotic Colonization
Status: COMPLETED
Conditions: Probiotics
Interventions: DRUG: Omeprazole|DIETARY_SUPPLEMENT: VSL #3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Collaborative Research Group for Necrotizing Enterocolitis
Status: COMPLETED
Conditions: Prematurity|Necrotizing Enterocolitis
Interventions: BIOLOGICAL: [5,5,5-2H3]leucine (stable isotope labeled leucine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Randomized Trial Comparing the Effectiveness of Continuous Paravertebral Infusion of Local Anesthetics Versus Intravenous Patient-controlled Analgesia on Acute and Chronic Neuropathic Pain After VATS Lobectomy
Status: COMPLETED
Conditions: Lung Neoplasms|Postoperative Pain
Interventions: DRUG: 0.5% ropivacaine|DRUG: Fentanyl 500mcg + acupan 160mg + nasea 0.6mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Adult Participants With Severe Alopecia Areata
Status: RECRUITING
Conditions: Alopecia Areata
Interventions: DRUG: Amlitelimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Therapy for Alcohol Dependence in Alaska Natives (Naltrexone/Sertraline)
Status: COMPLETED
Conditions: Alcoholism|Alcohol Dependence
Interventions: DRUG: sertraline|DRUG: naltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Myocardial Function & FFA Metabolism in HIV Metabolic Syndrome
Status: COMPLETED
Conditions: HIV Infections|Cardiovascular Disease|Insulin Resistance|HIV Lipodystrophy|The Metabolic Syndrome
Interventions: DRUG: Pioglitazone|BEHAVIORAL: Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Interventional, Monocentric, Double-blind Randomized Category 2b Study Evaluating the Evaluation of the Tolerance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post -Inflammatory Hyperpigmentation (Pih)) on the Face
Status: NOT_YET_RECRUITING
Conditions: Lentigo|Solar Lentigo|Post Inflammatory Hyperpigmentation
Interventions: DEVICE: CRYONOVE (EC14_4osc)|DEVICE: CRYONOVE (EC05osc)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Radiation Therapy in Treating Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Head and Neck Cancer
Interventions: DRUG: fluorouracil|DRUG: hydroxyurea|PROCEDURE: surgical procedure|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of EA Combined With NGF on Limb Function in Convalescent Patients With Ischemic Stroke
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: DRUG: nerve growth factor|DRUG: physiological saline|DEVICE: EA|DEVICE: sham EA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation Of The Effectiveness And Safety Of Anidulafungin Compared To Caspofungin For The Treatment Of Serious Fungal Infection Due To Candida In Patients With A Dysfunctional Immune System
Status: TERMINATED
Conditions: Fungemia|Neutropenia|Candidiasis
Interventions: DRUG: Active Anidulafungin|DRUG: Active Caspofungin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intermittent Oral Enteral Nutrition Tube in Tracheostomized Patients With Intracerebral Hemorrhage
Status: COMPLETED
Conditions: Intracerebral Hemorrhage
Interventions: DEVICE: Intermittent Oro-esophageal Tube Feeding|DEVICE: Nasogastric Tube Feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abscopal Effect of Radiation in Combination With rhGM-CSF for Metastatic Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer Metastatic
Interventions: RADIATION: Radiotherapy|DRUG: rhGM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effects of Ketoconazole on LBH589 in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Non-Hodgkin Lymphoma|Neoplasms
Interventions: DRUG: LBH589
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Family-based Cognitive-behavioral Therapy for Chronic Pediatric Headache and Anxiety
Status: COMPLETED
Conditions: Pediatric|Headache|Anxiety
Interventions: BEHAVIORAL: CBT or relaxation training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation for Refractory Trigeminal Neuralgia With a Demyelinating Pontine Lesion
Status: NOT_YET_RECRUITING
Conditions: Trigeminal Neuralgia
Interventions: DEVICE: Deep brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Randomized Study in Participants With Diabetic Retinopathy Without Center-involved Diabetic Macular Edema To Evaluate the Efficacy, Safety, and Pharmacokinetics of Ranibizumab Delivered Via the Port Delivery System Relative to the Comparator Arm
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Retinopathy
Interventions: DRUG: PDS Implant Pre-Filled with 100 mg/mL Ranibizumab|DRUG: Intravitreal Ranibizumab 0.5 mg Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Pharmacokinetic Profile of Etokimab (ANB020) in Adult Participants With Moderate-to-Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: Etokimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Pilot Study of Apremilast in Treatment of Rosacea
Status: COMPLETED
Conditions: Erythematotelangiectatic Rosacea|Papulopustular Rosacea
Interventions: DRUG: Apremilast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile App With Patient Financial Incentives for Adherence to Heart Failure Medications & Daily Self-Weighing
Status: WITHDRAWN
Conditions: Heart Failure|Heart Failure, Congestive|Heart Failure, Systolic
Interventions: BEHAVIORAL: Financial Incentive, Mobile Phone App, and Cellular Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study of a Structured Parent Intervention on Adolescent Weight Loss Modification Program.
Status: COMPLETED
Conditions: Pediatric Obesity|Impact of Parent Intervention on Adolescent Weight Loss
Interventions: BEHAVIORAL: Lifestyle Intervention|BEHAVIORAL: Parent Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Learn if Fianlimab and Cemiplimab Are Safe and Work Better Than Anti-PD1 Alone in Adult Participants With Resectable Stage 3 or 4 Melanoma
Status: NOT_YET_RECRUITING
Conditions: Melanoma
Interventions: DRUG: pembrolizumab|DRUG: fianlimab|DRUG: cemiplimab|DRUG: cemiplimab+fianlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Amitriptyline/Ketamine Topical Cream in Patients With Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy|Neuralgia
Interventions: DRUG: EpiCept NP-1 (4% Amitriptyline/ 2% Ketamine) Topical Cream|DRUG: placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Vitamin C on AKI Outcomes in Critically Ill Cirrhotics With Multidrug-resistant Bacterial Infections.
Status: COMPLETED
Conditions: Liver Cirrhosis
Interventions: DRUG: Vit C|DRUG: Standard medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Oral BTD-001 in Adults With Idiopathic Hypersomnia
Status: UNKNOWN
Conditions: Idiopathic Hypersomnia
Interventions: DRUG: Pentetrazol (PTZ)|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Promoting Alcohol Treatment Engagement Post-hospitalization
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: BEHAVIORAL: Brief Negotiated Interview (BNI)|BEHAVIORAL: BNI+facilitated provision of MAUD|BEHAVIORAL: Brief Negotiated Interview BNI+facilitated provision of MAUD+CBT4CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Mucosal Activity to Improve the Prognosis of Patients With Crohn's Disease Treated With Immunosuppressants
Status: TERMINATED
Conditions: Crohn's Disease|Mucosal Inflammation
Interventions: DRUG: ADALIMUMAB|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Tranexamic Acid or Placebo on Perioperative Bleeding in Adults Undergoing Liver Transplantation.
Status: UNKNOWN
Conditions: Hemorrhage
Interventions: DRUG: Tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Bupropion Hydrobromide in Adolescents and Children With Major Depressive Disorder
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: bupropion hydrobromide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I, Dose-escalation Trial of BAY1187982 in Subjects With Advanced Solid Tumors Known to Express Fibroblast Growth Factor Receptor 2 (FGFR2)
Status: TERMINATED
Conditions: Medical Oncology
Interventions: DRUG: BAY1187982
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nebulized Fentanyl in Healthy Volunteers
Status: NOT_YET_RECRUITING
Conditions: Analgesia|Emergencies
Interventions: DRUG: Fentanyl - Inhalation by facial nebulization|DRUG: Fentanyl - Nebulisation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT