pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of High Selenium Functional Food and Selenium Supplement
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: OTHER: high selenium functional food|DIETARY_SUPPLEMENT: selenium supplement|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the SETA LATECBA Stent Graft for EVAR in Subjects With AAA
Status: UNKNOWN
Conditions: Abdominal Aortic Aneurysm
Interventions: DEVICE: SETA LATECBA Stent Grafts
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pathological Complete Response Rate in Locally Advanced Breast Cancer With FEC, EC-T, or TC as Neoadjuvant Chemotherapy
Status: UNKNOWN
Conditions: Breast Cancer|Pathological Complete Response|Neoadjuvant Chemotherapy
Interventions: DRUG: Epirubicin|DRUG: Fluorouracil|DRUG: Docetaxel|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Shared-Decision Making in Reducing Decision Conflict on the Choice of Awakening Agent After General Anesthesia
Status: COMPLETED
Conditions: Decision Making, Shared
Interventions: OTHER: Shared decision making with the used of patient decision aids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Inspiratory Muscle Training on Blood Pressure Levels in Hypertensive Individuals
Status: UNKNOWN
Conditions: Hypertension
Interventions: OTHER: Inspiratory muscle training (IMT)|OTHER: Sham IMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study Evaluating the Efficacy of Radiotherapy With SIB-IMRT, Associated With Temozolomide in Glioblastomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma, Adult
Interventions: DEVICE: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Antihypertensive Regimens for Management of Hypertension in Pregnancy
Status: COMPLETED
Conditions: Hypertension in Pregnancy|Preeclampsia
Interventions: DRUG: Nifedipine|DRUG: Labetalol|DRUG: Methyldopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melphalan and Thiotepa Followed by Peripheral Stem Cell Transplantation in Treating Patients With Epithelial Ovarian Cancer in Complete Remission
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: melphalan|DRUG: thiotepa|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Peanuts and Neurocognitive / Cardiovascular Health in Black Individuals
Status: RECRUITING
Conditions: Cardiovascular Diseases|Hypertension|Cognitive Decline|Diet|Healthy
Interventions: DIETARY_SUPPLEMENT: Peanut group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Autologous Bone Marrow Aspirate Concentrate Injection for the Treatment of Early Osteoarthritis:Baghdad 2022
Status: COMPLETED
Conditions: Treatment Complication
Interventions: PROCEDURE: autologous bone marrow aspirate concentrate by centrifugation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Inhaled Glucocorticoids on the Postmenopausal Skeleton
Status: WITHDRAWN
Conditions: Osteoporosis
Interventions: DRUG: Budesonide|OTHER: Placebo Inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Bivalirudin in Late PCI for Oatients With STEMI
Status: UNKNOWN
Conditions: STEMI - ST Elevation Myocardial Infarction
Interventions: DRUG: Bivalirudin|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Assessment of DBLUS System in Adolescent and Adult Patients With Type 1 Diabetes and Assessment of Its Clinical Efficacy (DIABELOOP SP8)
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 1|Closed-Loop
Interventions: DEVICE: Open-loop condition|DEVICE: Closed-loop condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Quetiapine Extended Release (XR) in Bipolar Patients With Comorbid Generalized Anxiety Disorder (GAD)
Status: COMPLETED
Conditions: Bipolar Disorder|Anxiety|Anxiety Disorders|Substance Use Disorders
Interventions: DRUG: Quetiapine XR|DRUG: Placebo for quetiapine XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Sofosbuvir/Velpatasvir Fixed Dose Combination for 12 Weeks With Sofosbuvir and Ribavirin for 24 Weeks in Adults With Chronic Genotype 3 HCV Infection
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: SOF/VEL|DRUG: SOF|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TCI999 in the Efficacy Verification Program of Hair and Body Health Care
Status: COMPLETED
Conditions: Hair Loss
Interventions: DIETARY_SUPPLEMENT: TCI999 probiotic sachet|DIETARY_SUPPLEMENT: Placebo sachet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Multicenter Trial Assessing the Efficacy and Safety of tamOxifen Plus LY2228820 in Advanced or Metastatic Breast Cancer Progressing on aromatasE Inhibitors
Status: TERMINATED
Conditions: Postmenopausal|Metastatic Breast Cancer
Interventions: DRUG: Tamoxifen|DRUG: Ralimetinib (LY2228820 dimesylate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vasopressin or Norepinephrine in Vasoplegic Shock After Non-cardiac Surgery
Status: WITHDRAWN
Conditions: Circulatory Shock|Non-cardiac Surgery
Interventions: DRUG: Vasopressin|DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neural Correlates of Tactile Prediction
Status: UNKNOWN
Conditions: Neurodevelopmental Disorders|Premature Birth
Interventions: DEVICE: electroencephalography|DEVICE: Tactile stimulation|BEHAVIORAL: Attention Network task (computerized)|BEHAVIORAL: Head-toes-knees-schoulders|BEHAVIORAL: Laby 5-12|BEHAVIORAL: M-ABC 2|BEHAVIORAL: Stroop animals
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: BKM120+Abiraterone Acetate for Metastatic CRPC
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: BKM120|DRUG: Abiraterone|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial for Harm Reduction With Incentives & Vaping E-cigarettes
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Smoking Cessation
Interventions: OTHER: ENDS|OTHER: CI|OTHER: No ENDS|OTHER: NI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Antipsychotic Combination Treatment of Olanzapine and Amisulpride to Monotherapy
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Olanzapine|DRUG: Amisulpride|DRUG: Olanzapine and Amisulpride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inter-individual Physiological Response to a Training and Detraining Period in Cardiometabolic Risk Factors Subjects
Status: COMPLETED
Conditions: Vascular Disease, Peripheral|Physical Inactivity|Arterial Hypertension|Endothelial Dysfunction
Interventions: BEHAVIORAL: Exercise training intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Testing the Safety and Preliminary Efficacy of the New Drug ORY-2001 in Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Mild to Moderate Alzheimer's Disease
Interventions: DRUG: ORY-2001 Low dose|DRUG: ORY-2001 High dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thiol Disulfide Balance in Cervix Cancer
Status: COMPLETED
Conditions: Cervix Cancer|Oxidative Stress
Interventions: DIAGNOSTIC_TEST: Disulphide(μmol/L)|DIAGNOSTIC_TEST: Total Oxidant Capacity(μmolH2O2Equiv/L)|DIAGNOSTIC_TEST: Ischemia Modified Albumin(IU/mL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Investigational Drug in Osteoporosis (MK-0217-908)
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Placebo|DRUG: ibandronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Darolutamide Augments Standard Therapy for Localised Very High-Risk Cancer of the Prostate
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Darolutamide|DRUG: Placebo oral tablet|DRUG: Luteinizing Hormone-Releasing Hormone Analog|RADIATION: External Beam Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapy by Led (Light Emission Diode) in Cutaneous Lesion: in Vivo
Status: UNKNOWN
Conditions: Burn Injury
Interventions: OTHER: LED (Light Emission Diode)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Recombinant Human IL-15 (s.c. rhIL-15) and Alemtuzumab for People With Refractory or Relapsed Chronic and Acute Adult T-cell Leukemia (ATL)
Status: COMPLETED
Conditions: T-Cell Lymphoma Relapsed|Adult T-Cell Leukemia (ATL)|Peripheral T-Cell Lymphoma (PTCL)|Cutaneous T Cell Lymphoma (CTCL)|T-Cell Prolymphocytic Leukemia
Interventions: BIOLOGICAL: IL-15 plus|BIOLOGICAL: alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Vosaroxin and Cytarabine for the Treatment of Adults 60 Years of Age or Older With Previously Untreated AML
Status: TERMINATED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Vosaroxin and Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Routes of Administration of a Multimodal Analgesic Protocol in Postoperative Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section; Complications, Wound, Infection (Following Delivery)|Postoperative Pain|Spinal Anaesthesia During the Puerperium
Interventions: DRUG: Nefopam 20 MG/ML|DRUG: "Nefopam (Acupan)" 20 MG/ML Injectable Solution|DRUG: "Acetaminophen, (paracetamol)" 500Mg Tab|DRUG: (Acetaminophen "paracetamol") IV Soln 10 MG/ML|DRUG: (Piroxicam "piroxan") 20 MG Oral Tablet|DRUG: (Piroxicam "piroxan") 20Mg/1mL Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Breast Milk Sniffing And Tasting On Early Feeding Tips
Status: COMPLETED
Conditions: Breastfeeding|Odors, Body|Newborn; Vitality
Interventions: BEHAVIORAL: Breast Milk Odor Stimulation|BEHAVIORAL: Stimulation of Breast Milk Smell and Taste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cross-over Study of Armodafinil Treatment of Daytime Sleepiness Associated With Treated Nocturia
Status: COMPLETED
Conditions: Nocturia|Daytime Sleepiness
Interventions: DRUG: Armodafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Availability of the Enhanced Liver Fibrosis (ELF) Test Affects the Rate of Diagnosis of Nonalcoholic Steatohepatitis (NASH) With Fibrosis in Patients Referred to Hepatology
Status: UNKNOWN
Conditions: Fatty Liver|NAFLD
Interventions: DIAGNOSTIC_TEST: ELF Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Efficacy of Basic Life Support Education Among Teenagers
Status: RECRUITING
Conditions: Cardiopulmonary Resuscitation|Basic Life Support|Premedical Education|Study Skills
Interventions: OTHER: Software based feedback|OTHER: Instructor feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Learning Curves for Two Different Techniques in Vaginal Hysterectomy
Status: NOT_YET_RECRUITING
Conditions: Pelvic Organ Prolapse|Gynecologic Disorders|Surgery
Interventions: PROCEDURE: vaginal hysterectomy by bipolar vessels sealing|PROCEDURE: vaginal hysterectomy by traditional technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Wound Integrity for Clear Corneal Cataract Incisions
Status: COMPLETED
Conditions: Cataract
Interventions: PROCEDURE: pressure by a cotton swab|PROCEDURE: stromal hydration with the balanced salt solution（BSS）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life Study Using Gabapentin Versus Venlafaxine in Treating Hot Flashes in Patients With Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Gabapentin|DRUG: Venlafaxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strain for Risk Assessment and Therapeutic Strategies in Patients With Acute Heart Failure (STRATS-AHF) Registry
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure Acute|Heart Failure|Echocardiography
Interventions: DIAGNOSTIC_TEST: Echocardiography with speckle-tracking imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The EVOLVE II Clinical Trial To Assess the SYNERGY Stent System for the Treatment of Atherosclerotic Lesion(s)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: PROMUS Element Plus|DEVICE: SYNERGY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, PK, PD, Immunogenicity of N-Rephasin® SAL200 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers|Anti-Bacterial Agents|Methicillin-Resistant Staphylococcus Aureus|Methicillin-Sensitive Staphylococcus Aureus Infection
Interventions: BIOLOGICAL: N-Rephasin® SAL200|OTHER: INT200-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Synergy Between Patient and Clinician: Using a Trauma-Informed Care Plan
Status: NOT_YET_RECRUITING
Conditions: Trauma and Stressor Related Disorders|Violence, Structural|Violence, Domestic|Violence, Sexual
Interventions: OTHER: Trauma-informed Care Plan-
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Tocilizumab (RoActemra/Actemra) in Participants With Giant Cell Arteritis (GCA)
Status: COMPLETED
Conditions: Giant Cell Arteritis
Interventions: DRUG: Tocilizumab|DRUG: Prednisone|DRUG: Tocilizumab Placebo|DRUG: Prednisone Placebo|DRUG: Corticosteroids|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of iSONEP With & Without Lucentis/Avastin/Eylea to Treat Wet AMD
Status: COMPLETED
Conditions: Exudative Age-related Macular Degeneration
Interventions: DRUG: 4.0 mg iSONEP|DRUG: 0.5 mg iSONEP|DRUG: 0.5 mg Lucentis or 1.25 mg Avastin or 2 mg Eylea|DRUG: sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Computerized Assessment and Referral System Screener for Mental Health Evaluations in the Emergency Setting
Status: COMPLETED
Conditions: Mental Health
Interventions: BEHAVIORAL: Computerized Assessment and Referral System (CARS) Self-Assessment Screener|BEHAVIORAL: CARS-SA Summary Results
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: BIRB 796 BS Versus Placebo in Patients With Moderate to Severs Plaque-type Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: BIRB 796 BS, low dose|DRUG: BIRB 796 BS, medium dose 1|DRUG: BIRB 796 BS, medium dose 2|DRUG: BIRB 796 BS, high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: High-dose IFN and PEG IFN for Induction Therapy in Difficult to Treat Genotype 1 Patients With Chronic HCV
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Peginterferon alfa-2a|DRUG: Interferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial to Deprescribe for Older Patients With Polypharmacy
Status: COMPLETED
Conditions: Polypharmacy|Care Transitions|Geriatric Syndromes
Interventions: BEHAVIORAL: Shed-Meds: A Patient-Centered Deprescribing Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Examining Effects of a Therapeutic Focus on Positive Memories on Post-Trauma Health
Status: RECRUITING
Conditions: Stress Disorders, Post-Traumatic|Affect|Memory
Interventions: BEHAVIORAL: Processing of Positive Memories Technique (PPMT)|BEHAVIORAL: Supportive Counseling (SC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azithromycin Plus Chloroquine Versus Mefloquine In the Treatment of Uncomplicated P. Falciparum Malaria.
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Azithromycin plus Chloroquine|DRUG: Mefloquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Antioxidants on Human Macular Pigments
Status: COMPLETED
Conditions: Eye Health
Interventions: DIETARY_SUPPLEMENT: Lutein|DIETARY_SUPPLEMENT: Lutein plus green tea extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multiparametric Assessment of Peripheral Blood and Tissue Myeloid Cells. Phenotype for Precision Medicine in Patients With SARS-Cov-2 Infection
Status: RECRUITING
Conditions: COVID-19 Pneumonia
Interventions: OTHER: Immune-phenotyping of tissue and peripheral blood myeloid compartment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dasatinib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia That Did Not Respond to Imatinib Mesylate
Status: COMPLETED
Conditions: Accelerated Phase Chronic Myelogenous Leukemia|Blastic Phase Chronic Myelogenous Leukemia|Childhood Chronic Myelogenous Leukemia|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Meningeal Chronic Myelogenous Leukemia|Recurrent Childhood Acute Lymphoblastic Leukemia|Relapsing Chronic Myelogenous Leukemia|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: dasatinib|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Shock Wave Therapy for Pain-Relief After Arthroscopy for Osteochondral Lesions of the Talus
Status: UNKNOWN
Conditions: Osteochondral Lesion of Talus
Interventions: OTHER: Extracorporeal Shock Wave Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Esophageal Self-expandable Metal Stent for Malignant Strictures: a Safety and Efficacy Study
Status: NOT_YET_RECRUITING
Conditions: Oesophageal Cancer
Interventions: DEVICE: Esophageal self-expandable metal stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Rectus Muscle Approximation at Cesarean Delivery on Pain Perceived After Operation
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Rectus muscle approximation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Relationship Between Parameters of VOT Using NIRS and Clinical Outcomes in Pediatric Cardiac Surgery
Status: COMPLETED
Conditions: Congenital Heart Disease
Interventions: OTHER: vascular occlusion test using Pediatric SomaSensor for INVOS 5100C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Look at the Electrical Activity of the Heart in Subjects With Solid Tumor Cancers, Before and After Receiving the Study Treatment, GSK1120212
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: GSK1120212
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Codeine Plus Paracetamol Versus Placebo for PRK Post-operative Pain
Status: COMPLETED
Conditions: Myopia
Interventions: DRUG: Codeine|DRUG: paracetamol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial With Resolute Onyx in One Month Dual Antiplatelet Therapy (DAPT) for High-Bleeding Risk Patients
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Medtronic Resolute Onyx Zotarolimus-Eluting Coronary Stent System|DEVICE: Biosensors BioFreedom BA9 Drug Coated Coronary Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study Between Vacuum Therapy Dressing and Conventional Dressing in Management of Diabetic Wounds
Status: NOT_YET_RECRUITING
Conditions: Diabetic Wound
Interventions: DEVICE: vacuum device|OTHER: conventional dressing therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effectiveness of PTSD-treatment Compared to Integrated PTSD-PD-treatment in Adult Patients With Comorbid PTSD and BPD
Status: UNKNOWN
Conditions: Posttraumatic Stress Disorder (PTSD)|Borderline Personality Disorder (BPD)
Interventions: BEHAVIORAL: EMDR|BEHAVIORAL: DBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alternative Doffing Strategies to Prevent Healthcare Worker Self-Contamination When Using Personal Protective Equipment (PPE)
Status: COMPLETED
Conditions: Personal Protective Equipment
Interventions: BEHAVIORAL: Double Gloving Procedure|BEHAVIORAL: Intensified Hand Hygiene Procedure|BEHAVIORAL: One Step Procedure|BEHAVIORAL: CDC Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Protocol for Patients Above 75 Years Undergoing Emergency Laparotomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Frailty|Surgery--Complications|Outcome, Fatal|Frail Elderly Syndrome|Post-Op Complication|Gastro-Intestinal Disorder
Interventions: OTHER: Protocol for patients above 75 undergoing emergency laparotomy or laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Glucagon Administration on Energy Expenditure
Status: COMPLETED
Conditions: Hyperglucagonemia|Obesity
Interventions: DRUG: Glucagon|DRUG: Octreotide|BEHAVIORAL: Placebo|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Safety and Effectiveness of Durogesic (Fentanyl Transdermal Patch) in the Treatment of Children With Chronic Pain Requiring Long-term Narcotic Pain Relief Therapy
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: Durogesic® (fentanyl transdermal drug delivery system)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Allopurinol for Hypoxic-ischemic Brain Injury on Neurocognitive Outcome
Status: RECRUITING
Conditions: Encephalopathy, Hypoxic-Ischemic|Infant, Newborn, Diseases
Interventions: DRUG: Allopurinol|DRUG: Mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Infant Formula Feeding and Necrotizing Enterocolitis in Newborns
Status: UNKNOWN
Conditions: Necrotizing Enterocolitis|Necrotizing Enterocolitis of Newborn|Sepsis Newborn|Cows Milk Allergy
Interventions: DIETARY_SUPPLEMENT: Survey investigating Infant formula feeding in newborns
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Scalpel Versus Diathermy in Transverse Abdominal Skin Incision During Cesarean Section
Status: COMPLETED
Conditions: Skin Wound
Interventions: OTHER: Skin incision in Cesarean Section by Diathermy|OTHER: Skin incision in Cesarean Section by Scalpel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Kypho-Intra Operative Radiation Therapy (IORT) for Localized Spine Metastasis, Phase I/II Study
Status: COMPLETED
Conditions: Spinal Metastases
Interventions: RADIATION: Kypho-IORT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Oral Absorption of YM060 Between Orally-disintegrating Tablet and Conventional Tablet Under With Water Intake
Status: COMPLETED
Conditions: Healthy|Plasma Concentration of YM060
Interventions: DRUG: YM060
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: PeRinatal Outcomes With ACTive Versus Expectant Management of Women With Pre-labor Rupture Of Membranes
Status: NOT_YET_RECRUITING
Conditions: Rupture of Membranes; Premature|Distress; Fetal, Complicating Delivery|Delayed Delivery After Spontaneous or Unspecified Rupture of Membranes|Maternal Sepsis
Interventions: PROCEDURE: Induction of Labor IoL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sirolimus/Tacrolimus Combination After HLA Matched Related Peripheral Blood Stem Cell Transplants
Status: TERMINATED
Conditions: Acute Leukemia in Remission|Myelodysplastic Syndromes|Leukemia, Myeloid, Chronic-Phase|Leukemia, Myeloid, Accelerated-Phase
Interventions: DRUG: Sirolimus|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Parathyroid Autofluorescence Visualization in Thyroid Surgery: Impact on Postoperative Hypocalcemia
Status: COMPLETED
Conditions: Hypocalcemia
Interventions: DEVICE: Near Infrared Camera (NIR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Intervention Effect of a Hybrid Exercise Program on Frail Elderly
Status: COMPLETED
Conditions: Frail Elderly Syndrome
Interventions: BEHAVIORAL: Wu Qin Xi exercise|BEHAVIORAL: Wu Qin Xi, resistance training and endurance training|BEHAVIORAL: Resistance training and endurance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparison of Laparoscopic With Open Distal Gastrectomy in Advanced Gastric Cancer After Neoadjuvant Chemotherapy
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Neoadjuvant Chemotherapy|PROCEDURE: Laparoscopic gastrectomy|PROCEDURE: Open gastrectomy|DRUG: Adjuvant Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of Safety, Tolerability And Effectiveness Of Recifercept In Children With Achondroplasia
Status: TERMINATED
Conditions: Achondroplasia
Interventions: BIOLOGICAL: Recifercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Web-Based Physical Activity Intervention in Improving Long Term Health in Children and Adolescents With Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma In Situ|Hematopoietic and Lymphatic System Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Educational Intervention|OTHER: Internet-Based Intervention|OTHER: Internet-Based Intervention|OTHER: Laboratory Biomarker Analysis|DEVICE: Medical Device Usage and Evaluation|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Double-blind Trial of Buspirone for the Treatment of Anxiety in Youth With Autism Spectrum Disorders
Status: WITHDRAWN
Conditions: Autism Spectrum Disorder (ASD)
Interventions: DRUG: Buspirone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Breakthrough Bleeding During Extended Therapy Use With NuvaRing®
Status: COMPLETED
Conditions: Breakthrough Bleeding|Breakthrough Spotting
Interventions: OTHER: remove ring if bleeding or spotting occurs more than 5 days|OTHER: If bleeding does not remove ring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MEK Inhibitor FCN-159 To Treat Advanced Melanoma With NRAS-aberrant (Ia) and NRAS-mutant (Ib)or NF1-mutant(1b)
Status: SUSPENDED
Conditions: Melanoma
Interventions: OTHER: FCN-159
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Phase II Study on Continuous Circumferential Reinforcement of Laparoscopic Rectal Anastomosis to Prevent Complications
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Anastomotic Leakage|Operation
Interventions: PROCEDURE: Continuous Circumferential Reinforcement of the Anastomotic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety/Efficacy Study for the Treatment of Amyotrophic Lateral Sclerosis
Status: SUSPENDED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: BIOLOGICAL: autologous bone marrow-derived stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Results of Safety Guidewire Use in Ureteroscopic Stone Surgery
Status: UNKNOWN
Conditions: Urinary Stone
Interventions: PROCEDURE: Semirigid Ureteroscopy (URS) With Guide Wire|DEVICE: Semirigid Ureteroscopy (URS) Without Guide Wire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of CX-8998 in Adults With Tremor Associated With Parkinson's Disease
Status: WITHDRAWN
Conditions: Parkinson's Disease|Tremor
Interventions: DRUG: CX-8998|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mixed-method Evaluation of a Parental Psychoeducation Programme in a Suicide Risk Prevention Group
Status: RECRUITING
Conditions: Suicide Prevention
Interventions: BEHAVIORAL: Self-questionnaire WHOQOL-bref|BEHAVIORAL: Self-questionnaire Evaluation Inventory - Parent|BEHAVIORAL: quiz of knowledge|BEHAVIORAL: semi-structured interviews (qualitative)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pericardial Matrix With Mesenchymal Stem Cells for the Treatment of Patients With Infarcted Myocardial Tissue
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: COMBINATION_PRODUCT: PeriCord: Expanded and cryopreserved allogeneic umbilical cord Wharton´s jelly-derived adult mesenchymal stem cells colonized on human pericardial matrix.|PROCEDURE: Surgery by sternotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Uremic Toxins in the Intensive Care Units (ICU): Patients With Lactate Acidosis
Status: COMPLETED
Conditions: Acute Renal Failure
Interventions: PROCEDURE: Dialysis during 4 hours|PROCEDURE: Dialysis during 6 hours|PROCEDURE: Dialysis during 8 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Solriamfetol for Excessive Sleepiness Related to Shift Work Disorder
Status: RECRUITING
Conditions: Excessive Sleepiness|Shift-work Disorder
Interventions: DRUG: Solriamfetol Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phosphodiesterase Type 5 Inhibition With Tadalafil Changes Outcomes in Heart Failure: Extent of Renal Damage
Status: WITHDRAWN
Conditions: Heart Failure|Pulmonary Hypertension
Interventions: DRUG: Tadalafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Does Preop Midazolam Maintain Blood Glucose Norms in the Non Diabetic Perioperative Period
Status: COMPLETED
Conditions: Hernia
Interventions: OTHER: Normal saline|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between PEEK With Autogenous Bone Graft and PEEK With Xenograft in Maxillary Sinus Augmentation
Status: ACTIVE_NOT_RECRUITING
Conditions: Maxillary Sinus
Interventions: OTHER: PEEK With Autogenous Bone Graft|OTHER: PEEK With Xenograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Injection-Related InfectionS (IRIS) Program
Status: NOT_YET_RECRUITING
Conditions: Peer Support|Injection-related Infections|Infections|People Who Infect Drugs (PWID)
Interventions: OTHER: Holistic injection-related injection treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic and Pharmacokinetic Effects of Insulin Glulisine in Obese Subjects With Type 2 Diabetes After a Standard Meal in Comparison to Insulin Aspart
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin glulisine|DRUG: Insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Using Flexi-bar for Balance and Strength Training on the Balance and Muscle in Community-Dwelling Older Adults
Status: RECRUITING
Conditions: Flexi-bar|Vibration|Balance Training|Community-dwelling|Community Older|Strength Training
Interventions: DEVICE: Flexi-bar|OTHER: balance and strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Contribution of Erector Spina Plane Block to Analgesia for Myofascial Pain Syndrome
Status: COMPLETED
Conditions: Trigger Point|Myofascial Pain
Interventions: PROCEDURE: trapezius muscle injection|PROCEDURE: erector spina plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacology Study of Sapacitabine to Treat Advanced Leukemias or Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Leukemias|Myelodysplastic Syndromes
Interventions: DRUG: sapacitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Sulphadoxine-Pyrimethamine Use At Scale on Newborn Outcomes in Nigeria
Status: COMPLETED
Conditions: Malaria|Stillbirths
Interventions: DRUG: Community distribution of SP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cohort Study on the Age-related Macular Degeneration: Incidence and Research for Predisposing Factors
Status: COMPLETED
Conditions: Elderly French Population|Age-related Macular Degeneration
Interventions: OTHER: clinical parameters|OTHER: visual acuity exams|OTHER: retinophotography|OTHER: SD-OCT|OTHER: Intra ocular Pressure (IOP)|OTHER: retinal imaging (OPTOMAP)|OTHER: axial length (IOL master)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Interactive Perioperative Teaching Platform (IPTP)
Status: COMPLETED
Conditions: Tonsillar Hypertrophy|Adenoid Hypertrophy|Cryptorchidism|Hypospadias|Hydrocele
Interventions: OTHER: Interactive Perioperative Teaching Platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: TRI-REPAIR: TrIcuspid Regurgitation RePAIr With CaRdioband Transcatheter System
Status: COMPLETED
Conditions: Tricuspid Valve Insufficiency|Tricuspid Regurgitation|Tricuspid Valve Regurgitation|Cardiovascular Diseases|Heart Valve Diseases|Heart Diseases|Cardiac Valve Annuloplasty
Interventions: DEVICE: Cardioband Tricuspid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DCE-MRI and MBI in Assessing Tumor Response to Chemotherapy in Patients With Triple Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Estrogen Receptor Negative|HER2/Neu Negative|Progesterone Receptor Negative|Triple-Negative Breast Carcinoma
Interventions: PROCEDURE: Dynamic Contrast-Enhanced Magnetic Resonance Imaging|OTHER: Laboratory Biomarker Analysis|RADIATION: Scintimammography|DRUG: Technetium Tc-99m Sestamibi
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Navigated Laparoscopic Microwave Ablation of Tumor Mimics in Pig Liver - an Ex-vivo Trial
Status: COMPLETED
Conditions: Liver Cancer|Surgery|Navigation, Spatial
Interventions: PROCEDURE: navigated microwave ablation|PROCEDURE: ultrasound guided navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Cardiac Rehabilitation on Postoperatory of Coronary Artery Bypass Graft.
Status: COMPLETED
Conditions: Complication of CABG
Interventions: OTHER: Combination of four techniques of physiotherapy|OTHER: Combination of three techniques of physiotherapy|OTHER: Combination of two techniques of physiotherapy|OTHER: standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Incentive Spirometer as a Visual Feedback in Children With Spastic Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy, Spastic
Interventions: OTHER: Incentive spirometer as visual feedback|OTHER: Diaphragmatic breathing exercise (Mirror mediated therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating Effects of Multiple-Dose Administration of Itraconazole on the Single Dose Pharmacokinetics of Conjugated Estrogens/Bazedoxifene in Non-Obese and Obese Postmenopausal Women
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CE/BZA|DRUG: Itraconazole|DRUG: CE/BZA|DRUG: CE/BZA|DRUG: Itraconazole|DRUG: CE/BZA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Misoprostol Before Elective Caesarean Section for Decreasing the Neonatal Respiratory Morbidity
Status: UNKNOWN
Conditions: Transient Tachypnea Newborn|Cesarean Delivery Affecting Fetus
Interventions: DRUG: Misoprostol|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and Efficacy of Formoterol in a Daily Dose of 18 µg (9 µg Twice Daily) in Japanese Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Formoterol (OT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Potential Health Effects of Aronia Intake
Status: COMPLETED
Conditions: Health Effects of Aronia
Interventions: DIETARY_SUPPLEMENT: Aronia, washout and then placebo|DIETARY_SUPPLEMENT: Placebo, washout and then aronia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Decitabine + BUCY vs BUCY Conditioning Regimen for Myeloid Tumors Undergoing Allo-HSCT
Status: UNKNOWN
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation|Conditioning|Myeloid Tumors
Interventions: DRUG: Decitabine|DRUG: Busulfan (BU)|DRUG: Cyclophosphamide (CY)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact on Quality of Life of Long-term Ototoxicity in Cancer Survivors
Status: COMPLETED
Conditions: Quality of Life|Cancer|Hearing Loss, Sensorineural|Tinnitus, Subjective|Late Effect
Interventions: DIAGNOSTIC_TEST: High frequency audiometry|OTHER: Short-Form 36-Item Questionnaire (SF-36)|OTHER: Hearing handicap inventory for adults/elderly (HHIA/HHIE)|OTHER: Tinnitus handicap inventory (THI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of the Core Stabilization Training on Respiratory Parameters , Functional Capacity and Balance in Scoliosis
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: OTHER: Home Based Traditional Scoliosis Exercise|OTHER: Home Based Core Stabilization Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Tivozanib (AV-951) Plus FOLFOX6 in Subjects With Advanced Colorectal Cancer and Other Gastrointestinal Cancers
Status: COMPLETED
Conditions: Colorectal Cancer|Gastrointestinal Cancer
Interventions: DRUG: Tivozanib (AV-951) plus FOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maxillary Sinus Grafting With Deproteinized Porcine or Bovine Bone Mineral.
Status: COMPLETED
Conditions: Histomorphometry
Interventions: PROCEDURE: Maxillary sinus augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT