pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Lenalidomide, Rituximab, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Diffuse Large Cell or Follicular B-Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma
Interventions: BIOLOGICAL: pegfilgrastim|BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: lenalidomide|DRUG: prednisone|DRUG: vincristine sulfate|GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capillary Endoscopy Aspiration Catheter
Status: RECRUITING
Conditions: Microbiota|SIBO
Interventions: DEVICE: Capillary Endoscopy Aspiration Catheter|DEVICE: Endoscopy Aspiration Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Aramchol in Patients With Fatty Liver Disease or Nonalcoholic Steatohepatitis
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease|Nonalcoholic Steatohepatitis|Metabolic Syndrome
Interventions: DRUG: Aramchol|DRUG: Aramchol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Dose Escalation Study of LBQ707 (Gimatecan) Administered Orally Twice Per Week to Japanese Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: Gimatecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AK104 With Chemotherapy as Neoadjuvant and Adjuvant Therapy for Resectable Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: AK104|DRUG: Albumin-Bound Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dried Fruit on Cardiometabolic Risk Factors
Status: COMPLETED
Conditions: Cardiovascular Diseases|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Dried Fruit|OTHER: High Carbohydrate Snack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: CAPA-VU Trial Catheter Ablation in Paroxymal Atrial Fibrillation Based on UNIVU
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: CartoUnivu™|PROCEDURE: Ablation with Carto® 3 System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Bovine Lactoferrin on Feeding Intolerance and Intestinal Permeability in Preterm Neonates
Status: UNKNOWN
Conditions: Feeding Intolerance in Preterm|Intestinal Permeability in Preterm
Interventions: DRUG: Bovine Lactoferrin Supplement|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Phacoemulsification Versus Phacoemulsification & the iStent Implantation in POAG Patients
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma and Cataracts
Interventions: PROCEDURE: phacoemulsification alone|DEVICE: iStent Trabecular Micro-Bypass Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Geriatric Assessment to Predict Toxic Events in Older Patients With Non-Hodgkin Lymphoma With Imbedded Pilot Study of Pre-Phase Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Hodgkin Lymphoma (NHL)|Diffuse Large B-cell Lymphoma (DLBCL)
Interventions: DRUG: rituximab|DRUG: prednisone|BEHAVIORAL: Geriatric Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motivational Interventions and Physical Exercise in Patients With Fragility Fracture
Status: RECRUITING
Conditions: Fragility Fracture
Interventions: BEHAVIORAL: Physical and motivational follow-up treatment|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Breather Exerciser Trainer on Diaphragmatic Mobility And Thickness
Status: COMPLETED
Conditions: Aging Well
Interventions: OTHER: Breather Exerciser Trainer|OTHER: Conventional Breathing Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alveolar Socket Healing With and Without PRGF
Status: COMPLETED
Conditions: Alveolar Bone Resorption|Wound Heal
Interventions: OTHER: PRGF ENDORET® obtained from ENDORET® POST-EXTRACTION ALVEOLUS DENTAL KIT (KMU16)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab Combined With XELOX as Neoadjuvant Therapy for G/GEJ Adenocarcinoma
Status: RECRUITING
Conditions: Locally Advanced Gastric Adenocarcinoma
Interventions: DRUG: Tislelizumab combined with Oxaliplatin and Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Intubating Conditions Using Succinylcholine or Rocuronium for Rigid Bronchoscopy
Status: SUSPENDED
Conditions: Intubating Conditions|Postoperative Myalgia|Patient Satisfaction
Interventions: DRUG: Succinylcholine|DRUG: Rocuronium 0,3|DRUG: Rocuronium 0,6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Reduction of Zygomatic Arch in Zygomaticomaxillary Fractures
Status: COMPLETED
Conditions: Zygomatic Arch Reduction
Interventions: PROCEDURE: reduction of zygomatic arch in zygomaticomaxillary complex fracture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Testosterone and Athlete Response
Status: COMPLETED
Conditions: Athletic Performance|Testosterone|Women's Health: Female Athlete/Female Athlete Triad
Interventions: DRUG: Testosterone cream 1% (Andro-Feme® )|DRUG: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Hip Strength Training and Neuromuscular Electrical Stimulation on Functional Ankle Instability
Status: COMPLETED
Conditions: Ankle Injuries and Disorders
Interventions: PROCEDURE: Conventional ankle training|PROCEDURE: Hip strength training|PROCEDURE: Neuromuscular electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Positron Emission Tomography (PET) Study to Investigate the Brain Biodistribution of 18F GSK2647544 in Healthy Subjects to Determine Its Ability to Cross the Blood-brain-barrier.
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: GSK2647544 oral|DRUG: [18F]GSK2647544 IV bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of 18F-FLT in Pediatric Patients With Central Nervous System (CNS) Tumors
Status: TERMINATED
Conditions: Tumors of the Central Nervous System
Interventions: DRUG: 18F-FLT|RADIATION: PET Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of EsoGuard on Samples Collected Using EsoCheck Versus EGD for the Diagnosis of BE
Status: COMPLETED
Conditions: Barrett Esophagus|Esophageal Adenocarcinoma|Barretts Esophagus With Dysplasia|Barrett's Esophagus Without Dysplasia
Interventions: DEVICE: EsoGuard
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Polypill Versus Metformin in New Onset Type 2 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: GMRx-4 IR polypill - sitagliptin, dapagliflozin, metformin|DRUG: Metformin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Norepinephrine Versus Dopamine in Renal Transplant Recipients on Postoperative Graft Function
Status: UNKNOWN
Conditions: Renal Transplant
Interventions: DRUG: Norepinephrine|DRUG: Dopamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Two Different Collection Sets for Peripheral Blood Progenitor Cell Apheresis With Spectra Optia®
Status: COMPLETED
Conditions: Healthy Allogeneic Donors|Granulocyte Colony-stimulating Factor (G-CSF) Mobilized
Interventions: DEVICE: Spectra Optia® IDL-Set|DEVICE: Spectra Optia® Collection Set
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Comparision of Three Types of Toothbrushes Pulsar, Crossaction and Butler on Gingivitis and Plaque Removal
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Trial of Intranasal Versus Intravenous Naloxone in Level of Consciousness in Suspected Opioid Overdose
Status: COMPLETED
Conditions: Morphinan Opioid Overdose
Interventions: DRUG: Intranasal naloxone|DRUG: Intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Tidal Volume Monitoring Using the Linshom Respiratory Monitoring Device
Status: COMPLETED
Conditions: Pulmonary Ventilation|Capnography
Interventions: DEVICE: Linshom Respiratory Monitoring Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy Study Comparing Velcade Dexamethasone Thalidomide Versus Velcade Cyclophosphamide Dexamethasone as Induction Treatment in the Initial Management of Multiple Myeloma (IFM2013-04)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Thalidomide®|DRUG: Cyclophosphamide|DRUG: Velcade®|DRUG: Dexaméthasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Efficacy of Doxorubicin With Trabectedin Followed by Trabectedin Versus Doxorubicine in Patients With Leiomyosarcoma
Status: COMPLETED
Conditions: Uterine or Soft Tissue Leiomyosarcoma
Interventions: DRUG: Doxorubicin|DRUG: Trabectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Probiotics is More Effective in the Treatment of Infantile Colic
Status: COMPLETED
Conditions: Infantile Colic
Interventions: OTHER: L. acidophilus TYCA06, B. longum BLI-02 and B. bifidum VDD088|OTHER: L. reuteri GL-104|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Zoledronate With or Without Thalidomide in Treating Patients With Early Stage Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: Thalidomide|DRUG: zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Benefits of Vitamin D 5000 IU as Add on Therapy in the Management of Painful Diabetic Neuropathy Patient
Status: UNKNOWN
Conditions: Painful Diabetic Neuropathy
Interventions: DRUG: Standard therapy|DRUG: Vitamin D 5,000IU Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Costs of Enhanced Cocaine Treatments
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: BEHAVIORAL: Voucher Reinforcement|BEHAVIORAL: Extra Counseling Services|BEHAVIORAL: Voucher Reinforcement + Extra Counseling Services
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Left vs Left Randomized Clinical Trial
Status: RECRUITING
Conditions: Heart Failure|Heart Failure With Reduced Ejection Fraction|AV Block|LBBB|RBBB|Intraventricular Conduction Delay|Pacing-Induced Cardiomyopathy
Interventions: DEVICE: His/LBBP|DEVICE: BiVP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 24-month Real Life PErsistence Efficacy and Safety Study in IBD Patients in REMission Switched From Intravenous Infliximab to Subcutaneous Infliximab CT-P13 Remsima®SC
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammatory Bowel Diseases
Interventions: DRUG: Subcutaneous infliximab CT-P13 Remsima®SC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TEENCOPE: An Internet Coping Skills Training Program for Teens With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: TeenCope|BEHAVIORAL: Managing Diabetes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Triple or Quadruple Combination DAAs Treatment for Subjects With HCV GT 1b Infection
Status: WITHDRAWN
Conditions: HCV Infection
Interventions: DRUG: SOF+DCV+CDI-31244|DRUG: SOF+DCV+CDI-31244+ASV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transarterial Neoadjuvant Chemotherapy vs.Traditional Intravenous Chemotherapy For Locally Advanced Gastric Cancer With SOX+PD-1
Status: RECRUITING
Conditions: Locally Advanced Gastric Carcinoma
Interventions: DRUG: Oxaliplatin by arterial infusion plus S-1|DRUG: SOX neoadjuvant|DRUG: Sintilimab neoadjuvant|PROCEDURE: gastrectomy plus D2 lymph node dissection|DRUG: SOX adjuvant, Sequential S-1|DRUG: Sintilimab adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Personalized Instrument in Total Shoulder Arthroplasty The P.I.T.S.A. Study
Status: RECRUITING
Conditions: Shoulder Arthritis
Interventions: PROCEDURE: TSA standard|PROCEDURE: RTSA standard|PROCEDURE: TSA Blueprint|PROCEDURE: RTSA Blueprint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DARE-trial: A Trial Studying the Effect of the SeQuent Please Drug-eluting Balloon Compared to the Xience Prime Drug-eluting Stent for the Treatment of Stenosis of an Earlier Implanted Stent.
Status: UNKNOWN
Conditions: In-stent Restenosis
Interventions: DEVICE: PCI with a drug-eluting balloon|DEVICE: PCI with a drug-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Strategy for the Presentation of Oral Nutritional Supplements in Verrines for Managing Undernutrition in the Elderly Undergoing Follow-up Care and Geriatric Rehabilitation
Status: UNKNOWN
Conditions: Patients Hospitalized in Follow up Care or Rehabilitation
Interventions: OTHER: Food weighing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Prior Muscle Activation on the Compound Muscle Action Potential (CMAP)
Status: COMPLETED
Conditions: Focus: Effect of Muscle Activation on CMAP in Normal Humans
Interventions: OTHER: Hypothenar muscle activation--maximum, voluntary, isometric|OTHER: Thenar muscle activation--maximum, voluntary, isometric|OTHER: EDB muscle activation--maximum, voluntary, isometric|OTHER: Relaxation of muscle
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: GASA-CIR Trail (Guidance and the Symptoms of Acute Stress and Anxiety in Critically Ill Patients Relatives in Intensive Care Unit)
Status: UNKNOWN
Conditions: Acute Stress Disorder|Anxiety|Depression
Interventions: BEHAVIORAL: website and brochure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of Vonoprazan Compared to Placebo in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: Non-Erosive Gastro-Esophageal Reflux Disease|Heartburn
Interventions: DRUG: Vonoprazan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Caffeine Ingestion on the Biomechanics of Healthy Young Subjects
Status: COMPLETED
Conditions: Caffeine|Biomechanics|Fatigue|Injuries|Physical Activity
Interventions: DIETARY_SUPPLEMENT: Caffeine.|DRUG: Cellulose.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Two-dose Level Clinical Trial of Itraconazole in Patients With Metastatic Prostate Cancer Who Have Had Disease Progression While on Hormonal Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Itraconazole 200 mg|DRUG: Itraconazole 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Cerezyme® Infusions Every 4 Weeks Versus Every 2 Weeks in Type 1 Gaucher Disease
Status: COMPLETED
Conditions: Gaucher Disease, Type 1|Cerebroside Lipidosis Syndrome|Glucocerebrosidase Deficiency Disease|Glucosylceramide Beta-Glucosidase Deficiency Disease|Gaucher Disease, Non-Neuronopathic Form
Interventions: DRUG: Cerezyme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exablate Blood-Brain Barrier Disruption With Carboplatin for the Treatment of rGBM
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Glioblastoma
Interventions: DEVICE: Exablate BBBD|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of ABT-493 and ABT-530 in Subjects With Normal and Impaired Renal Function
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: ABT-493|DRUG: ABT-530
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Extraneal (Icodextrin)on Triglyceride Levels in PD Patients
Status: WITHDRAWN
Conditions: Peritoneal Dialysis|Hypertriglyceridemia
Interventions: DRUG: Extraneal (7.5% icodextrin) Peritoneal Dialysis Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Negative Pressure Wound Therapy in Flap Enhancement: Clinical Evaluation Study
Status: COMPLETED
Conditions: Surgical Flap|Negative-Pressure Dressings
Interventions: DEVICE: NPWT|OTHER: Conventional dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrated Neuromuscular Inhibition Versus Instrument Assisted Soft Tissue Mobilization in Chronic Back Pain
Status: NOT_YET_RECRUITING
Conditions: Chronic Non Specific Low Back Pain
Interventions: OTHER: Experimental: Group A: integrated neuromuscular inhibition technique|OTHER: Experimental: Group B :Instrument assissted soft tissue mobilization|OTHER: control group C conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Argatroban Injection in Pediatric Patients Requiring Anticoagulant Alternatives to Heparin
Status: COMPLETED
Conditions: Thrombocytopenia|Thrombosis
Interventions: DRUG: Argatroban
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Curcumin on Dose Limiting Toxicity and Pharmacokinetics of Irinotecan in Patients With Solid Tumors
Status: COMPLETED
Conditions: Advanced Colorectal Cancer
Interventions: DIETARY_SUPPLEMENT: curcumin|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Use of Atropine 0.01% in the Prevention and Control of Myopia (ATOM3)
Status: ACTIVE_NOT_RECRUITING
Conditions: Myopia
Interventions: DRUG: Atropine sulfate 0.01%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 18-week add-on to Metformin Comparison of Saxagliptin and Sitagliptin in Adult Patients With Type 2 Diabetes (T2D)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: saxagliptin|DRUG: sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Reuse of Oxaliplatin Hypersensitivity in Gastrointestinal Tumors
Status: NOT_YET_RECRUITING
Conditions: Gastrointestinal Tumors
Interventions: COMBINATION_PRODUCT: Anti-allergic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study to Investigate Efficacy, Safety and Tolerability of Iptacopan Compared With Placebo in Participants Aged 18 to 75 Years With gMG.
Status: RECRUITING
Conditions: Generalized Myasthenia Gravis
Interventions: DRUG: Iptacopan|OTHER: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Yo-Yo Sleep on Cardiometabolic Health
Status: RECRUITING
Conditions: Cardiometabolic Syndrome|Obesity
Interventions: BEHAVIORAL: Intermittent Short Sleep (ISS)|BEHAVIORAL: Social Jetlag (SJL)|BEHAVIORAL: Sustained Adequate Sleep (SAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Deep Learning Model Predicts Pathological Complete Response of Lung Cancer Following Neoadjuvant Immunochemotherapy
Status: NOT_YET_RECRUITING
Conditions: Deep Learning Model|Pathological Complete Response|Non-small Cell Lung Cancer|Neoadjuvant Chemoimmunotherapy
Interventions: DIAGNOSTIC_TEST: No interventions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility and Potential Effectiveness of a Case Management Intervention for Alcohol Use-Related Problems in Frequent Users of an Emergency Department: a Pilot Study
Status: TERMINATED
Conditions: Alcohol Drinking|Alcohol-Related Disorders
Interventions: BEHAVIORAL: Intensive Case Management
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab as Induction Treatment in Head and Neck Squamous Cell Carcinoma (HNSCC)
Status: COMPLETED
Conditions: Head and Neck Neoplasm
Interventions: DRUG: Cetuximab|DRUG: Docetaxel|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cup Revisions Through Anterior or Posterolateral Approach: an RCT
Status: ENROLLING_BY_INVITATION
Conditions: Loosening, Prosthesis
Interventions: PROCEDURE: Anterior approach|PROCEDURE: Posterolateral approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Extensive Stage Small Cell Lung Cancer|Hereditary Paraganglioma|Male Breast Cancer|Malignant Paraganglioma|Metastatic Gastrointestinal Carcinoid Tumor|Metastatic Pheochromocytoma|Pancreatic Polypeptide Tumor|Recurrent Breast Cancer|Recurrent Cervical Cancer|Recurrent Endometrial Carcinoma|Recurrent Gastrointestinal Carcinoid Tumor|Recurrent Islet Cell Carcinoma|Recurrent Neuroendocrine Carcinoma of the Skin|Recurrent Non-small Cell Lung Cancer|Recurrent Ovarian Epithelial Cancer|Recurrent Ovarian Germ Cell Tumor|Recurrent Pheochromocytoma|Recurrent Prostate Cancer|Recurrent Renal Cell Cancer|Recurrent Small Cell Lung Cancer|Recurrent Uterine Sarcoma|Regional Gastrointestinal Carcinoid Tumor|Regional Pheochromocytoma|Stage III Cervical Cancer|Stage III Endometrial Carcinoma|Stage III Neuroendocrine Carcinoma of the Skin|Stage III Ovarian Epithelial Cancer|Stage III Ovarian Germ Cell Tumor|Stage III Prostate Cancer|Stage III Renal Cell Cancer|Stage III Uterine Sarcoma|Stage IIIA Breast Cancer|Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Breast Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer|Stage IV Endometrial Carcinoma|Stage IV Neuroendocrine Carcinoma of the Skin|Stage IV Non-small Cell Lung Cancer|Stage IV Ovarian Epithelial Cancer|Stage IV Ovarian Germ Cell Tumor|Stage IV Prostate Cancer|Stage IV Renal Cell Cancer|Stage IV Uterine Sarcoma|Stage IVA Cervical Cancer|Stage IVB Cervical Cancer|Thyroid Gland Medullary Carcinoma
Interventions: DRUG: temsirolimus|DRUG: vinorelbine ditartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation in the Treatment of Nosocomial Sepsis Comparing Polymerase Chain Reaction With Conventional Blood Culture.
Status: COMPLETED
Conditions: Sepsis|Bacteremia|Fungemia
Interventions: OTHER: Antibiotic regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect and Mechanism of Computerized Cognition Training on the Incidence of Postoperative Cognitive Dysfunction After Cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: Postoperative Cognitive Dysfunction(POCD)
Interventions: BEHAVIORAL: Computerized cognition training|BEHAVIORAL: Basic training based on tablet computer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Post TAVI Coronary REVASCularisation Guided by Myocardial Perfusion Imaging: a Prospective Open Label Pilot Study: The REVASC-TAVI Study
Status: COMPLETED
Conditions: Severe and Symptomatic Aortic Stenosis|Stable Coronary Disease
Interventions: PROCEDURE: TAVI procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Remote Ischemic Pre-Conditioning in Moyamoya Disease Patients
Status: SUSPENDED
Conditions: Moyamoya Disease|Remote Ischemic Preconditioning
Interventions: PROCEDURE: Remote ischemic preconditioning|PROCEDURE: Sham remote ischemic preconditioning|PROCEDURE: Encephaloduroarteriosynangiosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine
Status: COMPLETED
Conditions: Mitochondrial Myopathies|Mitochondrial DNA Mutation|Mitochondrial Diseases|Chronic Progressive External Ophthalmoplegia With Myopathy|Kearns-Sayre Syndrome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot of Pediatric/Adult Study of Gene Expression Profiling and Clinical Characterization of Phototoxicity
Status: COMPLETED
Conditions: Healthy Volunteers|Fungal Infections|Bacterial Infections
Interventions: DRUG: Doxycycline|DRUG: Voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Regulation of Endogenous Glucose Production by Central KATP Channels
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus|Glucose Metabolism Disorders|Glucose, High Blood
Interventions: DRUG: Diazoxide|DRUG: Nicotinic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: LINFOTARGAM: Treatment With Chemotherapy Plus Rituximab and Highly Active Antiretroviral Therapy in Patients With Diffuse Large B Cell Lymphoma and Infection With the Human Immunodeficiency Virus (HIV)
Status: COMPLETED
Conditions: HIV Infections|Diffuse Large B Cell Lymphoma
Interventions: DRUG: R-CHOP|DRUG: Highly active antiretroviral therapy|DRUG: Central nervous system (CNS) prophylaxis|DRUG: Prophylaxis of opportunistic infections and support treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iodine Supplementation on Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Placebo|DRUG: iodine|DRUG: FEC/TE Placebo|DRUG: FEC/TE iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: USG Thoracolumbar Interfascial Plane (TLIP) in Lumbar Spine Surgeries
Status: COMPLETED
Conditions: Regional Anesthesia
Interventions: PROCEDURE: Thoracolumbar Interfascial Plane (TLIP) block|DRUG: I.V drug based multimodal approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hetrombopag in Secondary Prevention of XPO-1 Inhibitor-induced Thrombocytopenia in Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Chemotherapy-Induced Thrombocytopenia
Interventions: DRUG: Hetrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation of Acute Hamstring Injuries in Male Athletes
Status: COMPLETED
Conditions: Strains
Interventions: OTHER: Physiotherapy ASPETAR|OTHER: Physiotherapy ASPETAR+
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PHARM Optimal-HF Pilot
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: OTHER: Pharmacist-led HFrEF medication optimization|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Blood Folate and Homocysteine Levels Following Administration of Folic Acid According to Different Daily Dosing Schedules:a Simulation of Food Fortification
Status: COMPLETED
Conditions: Neural Tube Defects - Spina Bifida and Anencephaly
Interventions: DRUG: folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Antifungal Prophylaxis With Micafungin After Cord Blood Allogeneic Stem Cell Transplantation (MycaCOORD)
Status: COMPLETED
Conditions: Invasive Fungal Infection
Interventions: DRUG: Micafungin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Spread of COVID-19 in a University Community Setting: Role of a Low-Cost Reusable Form-Fitting Fabric Mask
Status: COMPLETED
Conditions: Covid19|SARS-CoV2 Infection
Interventions: DEVICE: Focal Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Effects of Viviscal Oral Supplements When Used by Females With Self-perceived Thinning Hair
Status: COMPLETED
Conditions: Hair Thinning
Interventions: DIETARY_SUPPLEMENT: Viviscal Oral Supplement Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non Invasive Mechanical Ventilation in Acute Cardiogenic Pulmonary Edema
Status: COMPLETED
Conditions: Acute Cardiogenic Pulmonary Edema
Interventions: OTHER: standard therapy (ST)|DEVICE: CPAP|DEVICE: BIPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Dose-titration of Pramlintide During Initiation of Therapy in Patients Trying to Improve Glucose Control
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Pramlintide acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TMC435-TiDP16-C113: A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics of TMC435
Status: COMPLETED
Conditions: Hepatitis C Virus
Interventions: DRUG: TMC435
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Connective Tissue Graft From Tuberosity Area and L-PRF Associated With Coronally Advanced Flap for Root Coverage
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Periodontal surgery with CAF+tSCTG|PROCEDURE: Periodontal surgery with CAF+L-PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Trial of KN026+KN046±XELOX in HER2-positive Locally Advanced GC
Status: RECRUITING
Conditions: HER2-positive Locally Advanced Resectable Gastric Cancer
Interventions: DRUG: KN026|DRUG: KN046|DRUG: XELOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Glutamatergic Neurotransmission of Severe TBI Patients
Status: SUSPENDED
Conditions: Disorder of Consciousness|Traumatic Brain Injury
Interventions: DRUG: Amantadine + L-DOPA|DRUG: NMDA blocker
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Topical KB105 for the Treatment of TGM1-deficient Autosomal Recessive Congenital Ichthyosis (ARCI)
Status: NOT_YET_RECRUITING
Conditions: Autosomal Recessive Ichthyosis
Interventions: BIOLOGICAL: KB105|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Whey Protein Effects on Gycemic Control and Vascular Function
Status: WITHDRAWN
Conditions: Blood Sugar (Glucose) Control|Blood Vessel (Vascular) Dysfunction
Interventions: DIETARY_SUPPLEMENT: Whey protein powder|DIETARY_SUPPLEMENT: Control protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Long-Term Out-of-Hospital Treatment of Patients With Proximal Deep Vein Thrombosis (DVT) Using Low-Molecular-Weight Heparin (LMWH) Versus LMWH Followed by Warfarin
Status: COMPLETED
Conditions: Thrombosis|Thromboembolism|Venous Thrombosis
Interventions: DRUG: Tinzaparin sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strengthening Transplantation Effects of Bone Marrow Mononuclear Cells With Atorvastatin in Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction|Stem Cell Transplantation|Angioplasty, Transluminal, Percutaneous Coronary
Interventions: DRUG: Atorvastatin and mononuclear cells transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Interproximal Plaque and Gingivitis Effects of Three Interdental Cleaning Modalities
Status: COMPLETED
Conditions: Gingivitis
Interventions: OTHER: Sonicare Interproximal (IP) Cleaning Prototype
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Structured Physical Activity Program on Bone Strength and Psycho-Motor Learning of Young Children
Status: UNKNOWN
Conditions: Bone Strength|Bone Density
Interventions: OTHER: Upper Limb Exercises|OTHER: Normal physical exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of EMDR Therapy, as Compared to Treatment as Usual, in Reducing Clinical Symptoms in People With HIV
Status: COMPLETED
Conditions: HIV/AIDS|Psychological Trauma|PTSD
Interventions: BEHAVIORAL: EMDR plus TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Means to Scale Early Childhood Development Interventions in Rural Kenya
Status: COMPLETED
Conditions: Early Child Development
Interventions: BEHAVIORAL: Group sessions|BEHAVIORAL: Group+Home sessions|BEHAVIORAL: Booster sessions|BEHAVIORAL: Fathers invited
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Back Squat Exercise Treatment for Low Back Pain: Clinical Trial
Status: COMPLETED
Conditions: Low Back Pain|Muscle Strength|Visceral Obesity|Spine Disease|Spine Degeneration|Postural Low Back Pain|Spine Deformity
Interventions: BEHAVIORAL: Experimental: Complete Group|BEHAVIORAL: Active Comparator: Restricted Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Financial Impact of an Evidenced-Based Adhesive Small Bowel Obstruction Management Protocol
Status: WITHDRAWN
Conditions: Intestinal Obstruction
Interventions: DRUG: Omnipaque|DRUG: MD-Gastroview
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Angiotensin Receptor-Neprilysin Inhibition in Chagas Cardiomyopathy With Reduced Ejection Fraction: ANSWER-HF.
Status: RECRUITING
Conditions: Chagas Cardiomyopathy
Interventions: DRUG: Sacubitril / Valsartan Oral Tablet [Entresto]|DRUG: Enalapril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Midodrine Hydrochloride in the Management of Refractory Ascites Due to Cirrhosis in Children
Status: UNKNOWN
Conditions: Refractory Ascites|Children, Only
Interventions: DRUG: Midodrine 2.5 mg tab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Efficacy and Safety of Dual Anticoagulants i.e. Rivaroxaban Plus Aspirin and Clopidogrel Plus Aspirin in Patients Suffering From an Acute Coronary Syndrome
Status: NOT_YET_RECRUITING
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Rivaroxaban 2.5 Mg Oral Tablet|DRUG: Clopidogrel tablet|DRUG: Aspirin tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn More About Treatment With Damoctocog Alfa Pegol, How it is Used in Every Day Practice ("Real-World"), and How Satisfied People Who Receive Damoctocog Alfa Pegol Are in United States (US) Hemophilia Treatment Centers
Status: TERMINATED
Conditions: Hemophilia A
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Compare SB12 (Proposed Eculizumab Biosimilar) to Soliris in Subjects With Paroxysmal Nocturnal Haemoglobinuria
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: SB12 (proposed eculizumab biosimilar)|DRUG: Soliris (eculizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Oral Hygiene Instructions in the Resolution of Peri-implant Mucositis
Status: NOT_YET_RECRUITING
Conditions: Peri-implant Mucositis
Interventions: BEHAVIORAL: OHI|PROCEDURE: OHI+PMPR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Analyse the Immediate Effect of Dry Needling and Extra Corporeal Shock Wave Therapy on Hand Grip Strength
Status: UNKNOWN
Conditions: Muscle Weakness Condition
Interventions: COMBINATION_PRODUCT: Dry needling and Extra corporeal Shock wave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pilot Study of Non-Viral, RNA-Redirected Autologous T Cells in Patients With Refractory or Relapsed Hodgkin Lymphoma
Status: TERMINATED
Conditions: Hodgkin Lymphoma
Interventions: BIOLOGICAL: CD19 RNA redirected autologous T-cells (RNA CART19 cells)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Laser Acupuncture on Neurophysiological Parameters of Median Nerve in Postpartum Women
Status: RECRUITING
Conditions: Neurophysiologic Abnormality
Interventions: DEVICE: laser acupuncture|DEVICE: night splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Ultrasonographic Assessment of Ipsilateral Axillary Lymph Nodes in Patients With Breast Cancer: A STARD Study
Status: UNKNOWN
Conditions: Multimodal Ultrasonographic Assessment of Axillary Lymph Nodes in Patients With Breast Cancer
Interventions: DIAGNOSTIC_TEST: Multimodal Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiation With Chemotherapy and a Study Drug to the Para-Aortic Nodes in Cervical Cancer
Status: WITHDRAWN
Conditions: Cervical Cancer
Interventions: PROCEDURE: Radiation Therapy|DRUG: Cisplatin|DRUG: Amifostine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron Absorption From a Wheat-based Instant Cereal:Gut and Stable Isotope Studies in Kenyan Infants
Status: COMPLETED
Conditions: Iron Absorption|Gut Microbiota
Interventions: DIETARY_SUPPLEMENT: FeFum and 7.5 g prebiotic mixture|DIETARY_SUPPLEMENT: FeFum and 3 g prebiotic mixture|DIETARY_SUPPLEMENT: Fefum and no prebiotic mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Structured Intervention on the Development of Self-Care Behaviors With AVF in HD Patients
Status: COMPLETED
Conditions: Arteriovenous Fistula|Hemodialysis
Interventions: BEHAVIORAL: Structured Intervention on Self-care with AVF (SISC-AVF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Olanzapine Plus Fosaprepitant Standard Antiemetic Therapy in the Prevention of Chemotherapy-induced Nausea and Vomiting in Patients Receiving High Emetic Risk Multi-day Chemotherapy: a Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 3 Study
Status: UNKNOWN
Conditions: Solid Tumor Patients Receiving High Emetic Risk Multi-day Chemotherapy
Interventions: DRUG: olanzapine plus fosaprepitant-based triple regimen|DRUG: placebo plus fosaprepitant-based triple regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Naldemedine in the Treatment of Opioid-induced Constipation
Status: COMPLETED
Conditions: Opioid-induced Constipation
Interventions: DRUG: Naldemedine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of Telerehabilitation as Modality of Patient Follow-up on the Waiting List of a Clinic
Status: COMPLETED
Conditions: Rehabilitation|Orthopedic Disorder
Interventions: OTHER: Phone call follow-up|OTHER: Telerehabilitation follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE