pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Longitudinal Assessment of Autonomic and Sensory Nervous System in ALS
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DIAGNOSTIC_TEST: Skin biopsy|DIAGNOSTIC_TEST: Cardiovascular Reflexes testing|DIAGNOSTIC_TEST: Administration of clinical scales evaluating autonomic symptoms, pain small fiber neuropathy symptoms|DIAGNOSTIC_TEST: Dinamic Sweat Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tocilizumab (TCZ) in New-onset Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|New-onset Type 1 Diabetes Mellitus|T1DM|T1D
Interventions: DRUG: Tocilizumab (TCZ)|DRUG: Placebo|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Rank Different Dosages of Antigen of GlaxoSmithKline (GSK) Biologicals' Investigational Respiratory Syncytial Virus (RSV) Vaccine (GSK3003891A), Based on Their Immune Response and Safety, When Administered to Healthy Adult Women
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSV Vaccine (GSK3003891A) formulation 1|BIOLOGICAL: RSV Vaccine (GSK3003891A) formulation 2|BIOLOGICAL: RSV Vaccine (GSK3003891A) formulation 3|DRUG: Placebo (Formulation buffer S9b)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Vaccination Against Influenza H1N1 in Patients With Inflammatory Bowel Diseases (IBD) Treated Immunomodulators and Biologics
Status: UNKNOWN
Conditions: Influenza H1N1
Interventions: BIOLOGICAL: Focetria (Monovalent MF59-Adjuvanted vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Body Composition Monitor(BCM) Guided Fluid Management in Maintenance Hemodialysis (MHD) Patients
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DEVICE: body bioimpedance spectroscopy device|DEVICE: Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Test How Well Different Doses of BI 3034701 Are Tolerated by Healthy Men and People With Overweight or Obesity
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: BI 3034701|DRUG: Placebo matching BI 3034701
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Onset of Effect of Mometasone Nasal Spray in Induced Allergic Rhinitis (Study P03431)
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Mometasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short-Term Application of Tocilizumab Following Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Tocilizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Microcurrent Treatment With and Without Resistance Exercises
Status: RECRUITING
Conditions: Sarcopenia|Ageing Well
Interventions: OTHER: Microcurrent treatment with resistance exercise programme|OTHER: Resistance exercise programme|OTHER: Microcurrent treatment|OTHER: No treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Navigated Early Survivorship Transition in Patients With Newly Diagnosed Cancer and Their Caregivers
Status: TERMINATED
Conditions: Cancer
Interventions: OTHER: Educational Intervention|OTHER: Follow-Up Care|PROCEDURE: Psychosocial Assessment and Care|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Spinal Cord Stimulation to Restore Cough
Status: COMPLETED
Conditions: Spinal Cord Injuries|Spinal Cord Diseases|Paralysis|Central Nervous System Diseases|Cough|Trauma, Nervous System|Wounds and Injuries
Interventions: PROCEDURE: Spinal Cord Stimulation to restore cough|DEVICE: Expiratory Muscle Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Balance, Muscular Electric Activity, Proprioception Before and After in the Vibratory Platform
Status: COMPLETED
Conditions: Therapeutics
Interventions: OTHER: Proprioceptive exercise on the vibratory platform|OTHER: Proprioceptive exercise on the ground (stable surface)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Anti-Inflammatory Effects Of Frequency Specific Microcurrent (FSM) In Osteoarthritic Adults
Status: RECRUITING
Conditions: Osteoarthritis
Interventions: DEVICE: Frequency Specific Microcurrent|DEVICE: Sham microcurrent treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Netarsudil for Prevention of Corticosteroid-induced Intraocular Pressure Elevation
Status: COMPLETED
Conditions: Fuchs' Endothelial Dystrophy|Bullous Keratopathy
Interventions: DRUG: Netarsudil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of a Family Strengthening Program Evaluation in Sierra Leone to Prevent Family Separation
Status: ACTIVE_NOT_RECRUITING
Conditions: Parent-Child Relations|Emotion Regulation|Economic Problems|Parenting
Interventions: BEHAVIORAL: Family strengthening program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Earlier Breast Cancer Detection Using Automated Whole Breast Ultrasound With Mammography, Including Cost Comparisons
Status: UNKNOWN
Conditions: Breast Neoplasms|Ultrasonography
Interventions: PROCEDURE: Comparison of Automated Whole Breast Ultrasound Screening with Blinded Screening Mammography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Comparison of MRI Artificial Intelligence-guided cTB Versus Routine cTB in Prostate Cancer Diagnosis
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: PROCEDURE: MRI-AI guided cognitive prostate targeted biopsy|PROCEDURE: Routine cognitive prostate targeted biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Compare the Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care (BSC) Versus Placebo Plus BSC in Participants With International Prognostic Scoring System Revised (IPSS-R) Low- or Intermediate-risk Myelodysplastic Syndrome (MDS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Oral Azacitidine|DRUG: Placebo for Oral Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Splenda: Effects on Blood Glucose Concentration, Appetite Scores and Subsequent Energy Intake
Status: COMPLETED
Conditions: Appetitive Behavior|Glucose Metabolism Disorders
Interventions: DIETARY_SUPPLEMENT: Splenda drink|DIETARY_SUPPLEMENT: Maltodextrin drink|DIETARY_SUPPLEMENT: High carbohydrate breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Meningococcal Quadrivalent CRM-197 Conjugate Vaccine Pregnancy Registry
Status: COMPLETED
Conditions: Meningococcal Disease|Pregnancy|Infections, Meningococcal
Interventions: BIOLOGICAL: Meningococcal quadrivalent CRM-197 conjugate vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 24-hour Efficacy and Ocular Surface With Talfuprost and Triple Combined Therapy
Status: COMPLETED
Conditions: Glaucoma|Ocular Surface Disease
Interventions: DRUG: tafluprost|DRUG: tafluprost and dorzolamide/timolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pevonedistat Alone and in Combination With Chemotherapy in Patients With Mesothelioma
Status: TERMINATED
Conditions: Mesothelioma
Interventions: DRUG: pevonedistat|DRUG: Pemetrexed and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Ductal Carcinoma In Situ|Invasive Breast Carcinoma|Multicentric Breast Carcinoma|Multifocal Breast Carcinoma|Synchronous Bilateral Breast Carcinoma
Interventions: DRUG: Anastrozole|DRUG: Exemestane|OTHER: Laboratory Biomarker Analysis|DRUG: Letrozole|OTHER: Quality-of-Life Assessment|DRUG: Systemic Chemotherapy|DRUG: Tamoxifen Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gut-brain Health Effects of PREbiotics in Older Adults With Suspected COgnitive DEcline
Status: RECRUITING
Conditions: Subjective Cognitive Decline
Interventions: DIETARY_SUPPLEMENT: Chicory inulin|DIETARY_SUPPLEMENT: Resistant dextrin|DIETARY_SUPPLEMENT: Seaweed polysaccharide|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Explore the Associations of Behavioral Factors With Treatment Adherence in Axial Spondyloarthritis Patients Treated With Biotherapy.
Status: UNKNOWN
Conditions: Axial Spondyloarthritis
Interventions: BEHAVIORAL: self-questionnaire to patients undergoing SpAax follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Laparoscopic Surgery VS Laparoscopic Surgery + Neoadjuvant Chemotherapy for T4 Tumor of the Colon Cancer
Status: UNKNOWN
Conditions: Colonic Neoplasms
Interventions: DRUG: XELOX or FOLFOX chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Diabetes Status Upon Oral Treatment With GABA in Patients With Longstanding Type-1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Gamma-Aminobutyric Acid (GABA)|DRUG: Alprazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manual Therapy and Strengthening for the Hip in Older Adults With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low-back Pain|Hip Impairments|Hip-spine Syndrome|Osteoarthritis
Interventions: BEHAVIORAL: Hip-focused rehabilitation intervention|BEHAVIORAL: Spine-focused rehabilitation intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Safety Study of New Sinecort Formulation Versus Positive Control
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dexpanthenol (Sinecort, BAY81-2996)|DRUG: Positive control, Na-laurylsulfat-solution|DEVICE: Untreated skin under application chamber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early In-hospital Initiation of Pharmacotherapy for Smoking Cessation, Patients After ACS
Status: UNKNOWN
Conditions: Acute Coronary Syndrome|Smoking Cessation
Interventions: DRUG: Varenicline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Abemaciclib and Pembrolizumab in Metastatic or Recurrent Head and Neck Cancer
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DRUG: Cohort 1 Not Previously Treated|DRUG: Cohort 2 Treated Previously
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Advanced Techniques for Single-fraction Palliative Radiotherapy Versus ASPIRE-single
Status: RECRUITING
Conditions: Palliative Radiotherapy|Radiotherapy, Intensity-Modulated
Interventions: RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Photobiomodulation for Executive Function in Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DEVICE: Transcranial Phoobiomodulation (tPBM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Haplo T-Cell Depleted Transplantation in High-Risk Sickle Cell Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Sickle Cell Disease
Interventions: DRUG: CD34 selected T-cell depleted allogeneic SCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osteopathic Medicine in Fibromyalgia Syndrome
Status: COMPLETED
Conditions: Fibromyalgia Syndrome
Interventions: PROCEDURE: Osteopathic treatment|PROCEDURE: Factitious osteopathic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Device for Bacteremia Prevention in Post Cardiac Surgical Intensive Care Unit Patients
Status: COMPLETED
Conditions: Infection|Heart; Surgery, Heart, Functional Disturbance as Result|Bacteremia
Interventions: DEVICE: Chlorhexidine flush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Influence of Prenatal and Early Childhood Home-Visiting by Nurses on Development of Chronic Disease
Status: RECRUITING
Conditions: Chronic Disease
Interventions: BEHAVIORAL: Transportation and Developmental Screening|BEHAVIORAL: Transportation, Screening, and Nurse-Visitation during Pregnancy and Infancy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase1a, Dose-escalation Study of NNI-362 in Healthy Aged Volunteers
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: NNI-362|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Internet-based Educational Program to Promote Self-Management for Teens With Hemophilia
Status: COMPLETED
Conditions: Hemophilia A
Interventions: OTHER: Teens Taking Charge: Managing Hemophilia Online- Online self-management intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Tocilizumab in Comparison to Etanercept in Participants With Rheumatoid Arthritis and Cardiovascular Disease Risk Factors
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Etanercept|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sprouting of Wheat on Postprandial Glycemic and Satiety Responses of Wheat Bread Products
Status: COMPLETED
Conditions: Blood Sugar
Interventions: OTHER: Bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Rescuer Fatigue Using Two Thumb Versus Two Finger Method During Simulated Neonatal Cardiopulomnary Resuscitation
Status: COMPLETED
Conditions: Cardiac Output, High
Interventions: BEHAVIORAL: Two Finger technique|BEHAVIORAL: Two Thumb Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Inhaled Nitric Oxide by Oxygen Hood in Neonates
Status: COMPLETED
Conditions: Respiratory Failure|Infant|Persistent Fetal Circulation
Interventions: DRUG: inhaled Nitric Oxide|DRUG: Oxygen (>90% by hood) - standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Scapular Mobilization on Shoulder Proprioception and Pain in Patients With Adhesive Capsulitis
Status: RECRUITING
Conditions: Adhesive Capsulitis
Interventions: PROCEDURE: Conventional physical therapy|PROCEDURE: Scapular mobilization.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Low-dose HCG as an Adjunct to Ovarian Stimulation in Subfertile Women Undergoing ART
Status: TERMINATED
Conditions: HCG; IVF; Pregnancy Rates; ART; Chorionic Gonadotropin
Interventions: DRUG: hCG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation Between Zirconia and Stainless Steel Crowns
Status: COMPLETED
Conditions: Tooth Diseases
Interventions: DEVICE: Stainless Steel Crown (Group A)|DEVICE: NuSmile Zirconia Crowns (Group B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin to Prevent Post-Operative Atrial Fibrillation
Status: RECRUITING
Conditions: Post-operative Atrial Fibrillation|CABG
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Objective Measurements of the Opacification of the Lens After Vitrectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Vitrectomy|Cataract
Interventions: PROCEDURE: Objective Scatter Index (OSI)|PROCEDURE: Average Lens Density (ALD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate Safety and Immune Response of Novartis Meningococcal ACWY Conjugate Vaccine In US Adolescents and Adults
Status: COMPLETED
Conditions: Meningococcal Infections|Meningococcal Meningitis
Interventions: BIOLOGICAL: MenACWY CRM|BIOLOGICAL: Meningococcal ACWY Conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study for the Ocular Toxocariasis Patients With the Pulmonary Toxocariasis, and Ocular Toxocariasis Cohort
Status: UNKNOWN
Conditions: Toxocariasis|Ocular Toxocariasis|Pulmonary Toxocariasis|Ground Glass Opacity (GGO)|Toxocara Canis Infection (Canine Roundworms)|Law Liver|Law Meat|Serum Toxocara Antibody|Toxocara Larva Migrans
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Omega-3 Fatty Acids on Kynurenine Metabolism and Mood
Status: UNKNOWN
Conditions: Stress-induced Mood|Kynurenine Pathway and Its Metabolites
Interventions: DIETARY_SUPPLEMENT: Omega-3 fatty acids|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: DRUG: Alemtuzumab|DRUG: Fludarabine|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sodium Bicarbonate Buccal Infiltration on the Success of Inferior Alveolar Nerve Block
Status: COMPLETED
Conditions: Local Anesthesia
Interventions: DRUG: sodium bicarbonate|DRUG: Lidocaine|DRUG: sterile distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Non-inferiority Study of Telemedicine Versus Conventional CBT-I in Recently Hospitalized Patients With Insomnia
Status: UNKNOWN
Conditions: Insomnia
Interventions: BEHAVIORAL: Telemedicine CBT-I|BEHAVIORAL: Conventional office-based CBT-I
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Emergency Department Stopping Elderly Accidents, Deaths and Injuries Program
Status: COMPLETED
Conditions: Accidental Falls|Falling Injury|Other and Unspecified Fall on Same Level
Interventions: BEHAVIORAL: Bedside Decision Aid|BEHAVIORAL: Control Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Specific Lipid Fractions-enriched Infant Formulae
Status: COMPLETED
Conditions: Infant Growth
Interventions: OTHER: Standard infant formula|OTHER: Standard infant formula with PL1|OTHER: Standard infant formula with PL2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Predicting Disease Progression and/or Recurrence in Cancer
Status: COMPLETED
Conditions: Patient Reported Outcome Measures|Colorectal Cancer|Pancreatic Cancer|Biliary Tract Cancer|Esophageal Cancer|Metastatic Cancer|Disease Progression|Survival Analysis
Interventions: BEHAVIORAL: Observational Cohort
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Pharmacokinetics and Safety of BLU-5937 in Healthy Adult Japanese and Caucasian Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BLU-5937
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: I SELECT - Irbesartan In Hypertensive Patients With Left Ventricular Hypertrophy
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Irbesartan (Aprovel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Vitamin D Content in Mushrooms
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Mushroom Vitamin D2|DIETARY_SUPPLEMENT: Cholecalciferol|DIETARY_SUPPLEMENT: Vitamin D2 - Ergocalciferol|DIETARY_SUPPLEMENT: Mushroom Extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect of Dietary Fat Type in Combination With High Protein on Plasma Homocysteine Levels
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Olive Oil, Palm Olein Oil, Coconut Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral Statins and Protection From Hearing Loss
Status: RECRUITING
Conditions: Sudden Sensorineural Hearing Loss
Interventions: DRUG: Statin|DRUG: methylprednisolone|DRUG: dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intermittent Auscultation Using Handheld Doppler: a Randomized Controlled Trial Comparing Perinatal Outcomes in Uganda
Status: COMPLETED
Conditions: Stillbirth|Neonatal Death
Interventions: DEVICE: Fetal heart rate Doppler|PROCEDURE: Partograph
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Just-In-Time Adaptive Interventions for Diabetic Patients
Status: NOT_YET_RECRUITING
Conditions: Diabetes|Self-Control|Telemedicine
Interventions: BEHAVIORAL: Just-in-time intervention|BEHAVIORAL: Active control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of the Safety and Tolerance of CAN04 in Combination With FOLFIRINOX in Subjects With Metastatic Pancreatic Ductal Adenocarcinoma
Status: COMPLETED
Conditions: Metastatic Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: CAN04|DRUG: FOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Clinical Validity of Konectom™ in Adults Living With Neuromuscular Disorders
Status: COMPLETED
Conditions: Spinal Muscular Atrophy
Interventions: DEVICE: Konectom NMD Application
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trial of Two Stem Cell Doses To Reduce Transplant Induced Symptom Burden
Status: COMPLETED
Conditions: Multiple Myeloma|Primary Amyloidosis
Interventions: DRUG: Melphalan|PROCEDURE: Stem Cell Infusion|BEHAVIORAL: Questionnaires|DRUG: Granulocyte-colony stimulating factor (G-CSF)|PROCEDURE: Apheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Umbilical-Cord-Derived Mesenchymal Stem Cell Therapy in Active Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: BIOLOGICAL: UCMSC group|OTHER: Control group(Normal saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Alternative Treatments of Vitamin D Deficiency
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: RADIATION: Narrowband UVB|DIETARY_SUPPLEMENT: Vitamin D and calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Risk Clinical Stratification of Sickle Cell Disease in Nigeria, Assessment of Efficacy/Safety of Hydroxyurea Treatment
Status: COMPLETED
Conditions: Sickle Cell Disease|Sickle Cell Anemia
Interventions: DRUG: hydroxyurea
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Adjuvant Chemotherapy With or Without PD-1 Inhibitors and Chemoradiotherapy in Resected pN3 Gastric (G) or GEJ Adenocarcinoma
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: PD-1 inhibitor|DRUG: Oxaliplatin|DRUG: Capecitabine|DRUG: Tegafur-gimeracil-oteracil potassium|DRUG: 5-FU|RADIATION: Radiotherapy|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sevoflurane in Subarachnoidal Haemorrhage
Status: WITHDRAWN
Conditions: Subarachnoid Haemorrhage (SAH)
Interventions: DRUG: Sevoflurane|DRUG: Propofol|DRUG: Midazolam|DEVICE: MIRUS™System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Buprenorphine Delivered by Buprenorphine Transdermal System (BTDS) on QT Intervals in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Buprenorphine transdermal patch|DRUG: Matching placebo transdermal patch|DRUG: Avelox (moxifloxacin hydrochloride) tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of SWK002 in Patients With D2T-Rheumatoid Arthritis
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Anti-CD19 CART cells will be given IV at split doses.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptance and Commitment Therapy and Cognitive Behavioral Therapy for Chronic Pain
Status: UNKNOWN
Conditions: Chronic Pain
Interventions: BEHAVIORAL: ACT-based intervention|BEHAVIORAL: CBT-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Therapy With Toripalimab and JS004 Combined With Etoposide and Platinum Chemotherapy for Limited-stage Small Cell Lung Cancer : A Phase 2 Trial
Status: RECRUITING
Conditions: Limited Stage Small Cell Lung Cancer
Interventions: DRUG: JS004|DRUG: Toripalimab|PROCEDURE: surgery|DRUG: Etoposide|DRUG: Platinum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Determine the Most Effective Dose of Arformoterol for Treating Acute Asthmatic Patients
Status: TERMINATED
Conditions: Acute Asthma
Interventions: DRUG: arformoterol (RR formoterol)|DRUG: placebo|DRUG: levalbuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of AK101 in Subjects With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: BIOLOGICAL: AK101|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Blood and Tissue Samples From Patients With Uterine Cancer
Status: COMPLETED
Conditions: Endometrial Serous Adenocarcinoma|Stage I Uterine Corpus Cancer|Stage II Uterine Corpus Cancer|Stage III Uterine Corpus Cancer|Stage IV Uterine Corpus Cancer
Interventions: OTHER: Diagnostic Laboratory Biomarker Analysis|OTHER: Immunohistochemistry Staining Method|OTHER: Medical Chart Review|GENETIC: Microarray Analysis|OTHER: Study of Socioeconomic and Demographic Variables|GENETIC: Western Blotting
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Pharmacokinetic Interaction Between AD-2011 and AD-2012
Status: COMPLETED
Conditions: Hyperlipidemias|Hypertension
Interventions: DRUG: AD-2011 10/20 mg|DRUG: AD-2012 80mg|DRUG: AD-2011 10/20 mg + AD-2012 80mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imiquimod to Detect Residual Lesions and Prevent Recurrence of Lentigo Maligna
Status: UNKNOWN
Conditions: Lentigo Maligna
Interventions: DRUG: Imiquimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hormone Therapy Plus Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia
Status: UNKNOWN
Conditions: Leukemia
Interventions: DRUG: asparaginase|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: dexamethasone|DRUG: doxorubicin hydrochloride|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: pegaspargase|DRUG: prednisolone|DRUG: thioguanine|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of a Single Intravenous Infusion of BAY 79-4980
Status: COMPLETED
Conditions: Hemophilia A
Interventions: BIOLOGICAL: Recomb. Factor VIII (Kogenate FS Liposome, BAY79-4980)|BIOLOGICAL: Recomb. Factor VIII (Kogenate FS Liposome, BAY79-4980)|BIOLOGICAL: Recombinant Factor VIII (Kogenate FS, BAY14-2222)|BIOLOGICAL: Recombinant Factor VIII (Kogenate FS, BAY14-2222)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Taiwan Associated Genetic and Nongenetic Small Vessel Disease
Status: RECRUITING
Conditions: Cerebral Small Vessel Diseases|Cadasil|HTRA1-Related Autosomal Dominant Cerebral Angiopathy|COL4A1-Related Brain Small Vessel Disease With Haemorrhage|Fabry Disease|Magnetic Resonance Imaging|Next-generation Sequencing|Stroke
Interventions: DIAGNOSTIC_TEST: MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NBI-98854 for the Treatment of Tardive Dyskinesia in Subjects With Schizophrenia or Schizoaffective Disorder (KINECT Study)
Status: COMPLETED
Conditions: Tardive Dyskinesia
Interventions: DRUG: NBI-98854|DRUG: NBI-98854|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of an Oncofetal Antigen Multi-Peptide Immunotherapy in Subjects With Hematologic Cancer
Status: UNKNOWN
Conditions: Acute Myelogenous Leukemia (AML)|Multiple Myeloma (MM)|Myelodysplastic Syndrome (MDS)|Smoldering Multiple Myeloma (sMM)
Interventions: DRUG: Sargramostim|DRUG: BB-MPI-03|DRUG: Montanide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sensitivity of Project: EVO Monitor Cognitive Measurements to Pharmacological Agents
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Methylphenidate|DRUG: Triazolam|OTHER: Project: EVO|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ZEN003694 Combined With Talazoparib in Patients With Recurrent Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Cancer
Interventions: DRUG: ZEN003694|DRUG: Talazoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Short-Term Dynamic Psychotherapy (ISTDP) for Anxiety Diagnoses in a Primary Care Setting
Status: NOT_YET_RECRUITING
Conditions: Psychotherapy|Anxiety Disorders|Psychiatric &or Mood Disorder
Interventions: OTHER: Intensive Short-Term Dynamic Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Novel Long Lasting Insecticidal Net and Indoor Residual Spray Product
Status: COMPLETED
Conditions: Malaria|Anaemia
Interventions: OTHER: Olyset Plus LLIN|OTHER: Conventional Olyset LLIN|OTHER: IRS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Immunomodulatory Effects of Dexmedetomidine Infusion
Status: UNKNOWN
Conditions: Major Abdominal Surgery
Interventions: DRUG: Dexmedetomidine|DRUG: 0.9% sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Bcl-2 Inhibitor BGB-11417 in Participants With Mature B-Cell Malignancies
Status: RECRUITING
Conditions: Mature B-Cell Malignancies
Interventions: DRUG: BGB-11417|DRUG: Zanubrutinib|DRUG: obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Androgen Administration on Inflammation in Normal Women
Status: COMPLETED
Conditions: Hyperandrogenism
Interventions: DIETARY_SUPPLEMENT: Dehydroepiandrosterone (DHEA)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I Study of the Combination of Afatinib and Ruxolitinib in Patients With Treatment-refractory Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: NSCLC
Interventions: DRUG: Afatinib plus Ruxolitinib combination therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, 2x2 Factorial Design Biomarker Prevention Trial of Low-dose ASA and Metformin in Stage I-III Crc Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Tertiary Prevention in Colon Cancer
Interventions: DRUG: ASA|DRUG: MET|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Timecost of Intranasal Versus Intravenous Analgesia in Traumatic Pain
Status: RECRUITING
Conditions: Acute Pain Due to Trauma|Analgesia
Interventions: OTHER: Intravenous administration|OTHER: Intranasal administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating in Cirrhotics With Refractory Vasoplegia the Effect of Methylene Blue
Status: COMPLETED
Conditions: Septic Shock|Vasoplegia|Cirrhosis, Liver|Refractory Shock
Interventions: DRUG: Methylene Blue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Satavaptan in the Prevention of Ascites Recurrence in Patients With Ascites Due to Cirrhosis of the Liver
Status: TERMINATED
Conditions: Ascites|Liver Cirrhosis
Interventions: DRUG: Satavaptan|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aspirin Dose and Atherosclerosis in Patients With Heart Disease
Status: COMPLETED
Conditions: Cardiovascular Diseases|Atherosclerosis|Myocardial Infarction
Interventions: DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iberdomide Combined With Low-dose Cyclophosphamide and Dexamethasone
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Iberdomide plus low-dose cyclophosphamide and dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nurturing Healthy Teachers
Status: UNKNOWN
Conditions: Nutrition, Healthy|Mental Health Wellness 1|Diabetes Mellitus Risk|Obesity
Interventions: BEHAVIORAL: Brighter Bites (BB) Produce Distribution|BEHAVIORAL: Brighter Bites (BB) Nutrition Education|BEHAVIORAL: Create Healthy Futures (CHF) Weekly Wellness Groups|BEHAVIORAL: Create Healthy Futures (CHF) Web-Based Module
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Cream for Moisture Associated Skin Damage From Fecal Incontinence and/or Diarrhea
Status: NOT_YET_RECRUITING
Conditions: Incontinence-associated Dermatitis|Moisture Associated Skin Damage (MASD) (E.G., Incontinence-Associated Dermatitis [IAD], Perspiration, Drainage)|Fecal Incontinence Incontinence-associated Dermatitis
Interventions: OTHER: MASD Control Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Radio Frequency Ablation for Atrial Flutter With Magnetic Resonance Guidance and Tracking
Status: TERMINATED
Conditions: Atrial Flutter
Interventions: PROCEDURE: ablation for typical atrial flutter|DEVICE: Vision Ablation Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrical Stimulation With Different Currents: the Effects on Force, Tolerance and Fatigue in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Neo-Russian|DEVICE: Aussie|DEVICE: RBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Dietary Fiber Supplement on the Intestinal Microbiota Among Schizophrenia Patients
Status: UNKNOWN
Conditions: Schizophrenia|Central Obesity
Interventions: DIETARY_SUPPLEMENT: dietary fiber
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Quality Assessment in Endoscopic Retrograde Cholangiopancreatography(ERCP)
Status: COMPLETED
Conditions: Cholangiopancreatography, Endoscopic Retrograde|Common Bile Duct Lithiasis|Biliary Strictures|Bile Duct and Pancreatic Tumors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2, Single Arm Study of Cabozantinib in Patients With Hepatocellular Carcinoma Who Have Received Prior Atezolizumab and Bevacizumab
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma Non-resectable
Interventions: DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Pre-menopausal Patients With Advanced ER and PR + BC Treated With Arimidex Plus Zoladex
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Anastrozole and goserelin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Accelerated 3 Fraction Photon,Proton or Brachytherapy for Early Invasive and Noninvasive Breast Ca
Status: COMPLETED
Conditions: Breast Cancer
Interventions: RADIATION: Brachytherapy APBI|RADIATION: 3D-CRT (photon) APBI|RADIATION: Proton APBI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Prucalopride to Treat Chronic Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Prucalopride|OTHER: Placebo|DRUG: Prucalopride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acu-TENS to Improve the Sleep Quality in People With Stroke
Status: RECRUITING
Conditions: acuTENS|Sleep Quality|Stroke
Interventions: DEVICE: Acu-TENS|DEVICE: Sham Acu-TENS|OTHER: SHP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: In Nursing Students, The Effect of Disaster Nursing Training Program on General Disaster Preparedness Belief State, Disaster Response Self-Efficiency and Psychological Resilience
Status: UNKNOWN
Conditions: General Disaster Preparedness Belief State|Disaster Response Self-Efficiency|Psychological Resilience|Nursing Students
Interventions: OTHER: Disaster nursing and management training will be given to students using Jenning's Disaster Nursing and Management Model.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Carpal Stim in Treating Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: PRF stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Cobicistat-boosted Atazanavir Compared to Ritonavir-boosted Atazanavir in Combination With Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naive Adults
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: COBI|DRUG: RTV|DRUG: ATV|DRUG: FTC/TDF|DRUG: COBI placebo|DRUG: RTV placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Operative Imaging After Urethroplasty With Peri-catheter Retrograde Urethrography Or Trial of Voiding With Voiding Cysto-urethrography
Status: COMPLETED
Conditions: Urethral Stricture
Interventions: PROCEDURE: Post-urethroplasty urethrography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Alemtuzumab in Pediatric Intestinal Transplantation
Status: COMPLETED
Conditions: Evidence of Liver Transplantation|Rejection|ALEMTUZUMAB
Interventions: DRUG: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT