pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of 3 Subcutaneous and 1 Intravenous Dose of E6011 in Subjects With Active Crohn's Disease
Status: WITHDRAWN
Conditions: Crohn's Disease
Interventions: DRUG: E6011|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pancreatic Cancer and Synchronous Liver Metastases Resection Following Neoadjuvant FOLFIRINOX
Status: RECRUITING
Conditions: Pancreas Adenocarcinoma|Pancreas Metastases|Pancreas Cancer
Interventions: PROCEDURE: Pancreatic resection and non-anatomic liver resections.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Alternative Antiandrogen (AA) Therapy and Early Initiating of Enzalutamide for Castration-resistant Prostate Cancer (CRPC) After Combined Androgen Blockade (CAB) Therapy.
Status: COMPLETED
Conditions: Castration-resistant Prostate Cancer
Interventions: DRUG: Enzalutamide|DRUG: Flutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise, Creatine and Coenzyme Q10 for Childhood Myositis
Status: COMPLETED
Conditions: Myositis, Juvenile
Interventions: DIETARY_SUPPLEMENT: creatine monohydrate|DIETARY_SUPPLEMENT: ubiquinol|DIETARY_SUPPLEMENT: glucose tablet|DIETARY_SUPPLEMENT: gel capsule|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Assessing the Effect of Medications to Prevent Fever on Prevenar 13®
Status: COMPLETED
Conditions: Pneumococcal Vaccines
Interventions: BIOLOGICAL: 13-valent pneumococcal conjugate vaccine|BIOLOGICAL: INFANRIX hexa|DRUG: Paracetamol|BIOLOGICAL: 13-valent pneumococcal conjugate vaccine|BIOLOGICAL: INFANRIX hexa|DRUG: Ibuprofen|BIOLOGICAL: 13-valent pneumococcal conjugate vaccine|BIOLOGICAL: INFANRIX hexa|DRUG: Paracetamol|BIOLOGICAL: 13-valent pneumococcal conjugate vaccine|BIOLOGICAL: INFANRIX hexa|DRUG: Ibuprofen|BIOLOGICAL: 13-valent pneumococcal conjugate vaccine|BIOLOGICAL: INFANRIX hexa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Autogenous Dentin Matrix Versus Bovine-Derived Xenograft for Socket Preservation
Status: UNKNOWN
Conditions: Alveolar Bone Resorption
Interventions: PROCEDURE: socket preservation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real-life Evaluation of the Effect of ADT in Prostate Cancer Patients in Asia (READT Asia Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: PROCEDURE: Androgen deprivation therapy - bilateral orchidectomy|DRUG: Androgen deprivation therapy - GnRH agonist|DRUG: Androgen deprivation therapy - GnRH antagonist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study, Non Inferiority Between Noex® 50µg Versus Busonid® 50µg in Treatment of Allergic Rhinitis
Status: WITHDRAWN
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: Budesonid 50mcg (Noex)|DRUG: Budesonid 50mcg (Busonid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of Assessing During Peer Review the CONSORT Checklist Submitted by Authors
Status: COMPLETED
Conditions: Peer Review, Publishing|Completeness of Reporting
Interventions: BEHAVIORAL: Evaluation of reporting inconsistencies|BEHAVIORAL: Standard Peer Review.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pectoralis Nerve Block and Quality of Recovery in Mastectomy Patients
Status: RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: PECs block|OTHER: Not receiving PECs Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multicenter, Prospective, Phase III Randomized Controlled Clinical Study for the Treatment of N2-3 Nasopharyngeal Carcinoma Patients
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma|Neoadjuvant Chemotherapy
Interventions: DRUG: 4 cycles of Neoadjuvant Chemotherapy With Definitive Radiotherapy|DRUG: 3 cycles of Neoadjuvant Chemotherapy With concurrent chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sargramostim Following Allogeneic Bone Marrow Transplantation in Treating Patients With Chronic Myelogenous Leukemia
Status: TERMINATED
Conditions: Leukemia
Interventions: BIOLOGICAL: sargramostim|BIOLOGICAL: therapeutic allogeneic lymphocytes|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: in vitro-treated bone marrow transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Transdermal and Oral Estrogens in Adolescent Girls With Ovarian Failure
Status: COMPLETED
Conditions: Ovarian Failure, Premature
Interventions: DRUG: 17beta Estradiol|DRUG: Conjugated estrogens|DRUG: 17Beta Estradiol - transdermal|DRUG: Progesterone, micronized
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Catheter Ablation Strategy in Vasovagal Syncope
Status: COMPLETED
Conditions: Syncope, Vasovagal
Interventions: PROCEDURE: cardiac ganglion plexus ablation(cardioneuroablation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Vitamin D Supplementation to Male HIV Sero-positive Patients
Status: COMPLETED
Conditions: HIV Seropositive
Interventions: DRUG: Rocaltrol|DRUG: Vitamin D|DRUG: Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SHR-1210 in Combination With GEMOX in Patients With Advanced BTC
Status: COMPLETED
Conditions: Biliary Tract Cancer|Cholangiocarcinoma
Interventions: DRUG: SHR-1210+GEMOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Pilot Study of an ART Bridging Regimen in Highly Experienced Patients Unable to Achieve Viral Suppression
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: 3TC, TDF, NLV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of 'SESL01' Lens on Computer Vision Syndrome
Status: RECRUITING
Conditions: Computer Vision Syndrome
Interventions: DEVICE: Super enhanced single vision lens 01 for spectacles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer Previously Treated With Irinotecan
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFOX regimen|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Multi-Center Evaluation of the ENSEAL X1 Large Jaw Tissue Sealer
Status: COMPLETED
Conditions: Colectomy; Gynecological; Thoracic
Interventions: DEVICE: ENSEAL X1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breaking Sitting and Metabolic Health in Sedentary Overweight and Obese Adults
Status: COMPLETED
Conditions: Metabolic Health|Gut Hormones|Energy Balance
Interventions: BEHAVIORAL: Prolonged sitting|BEHAVIORAL: Breaking sitting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Postpartum Low-Dose Aspirin After Preeclampsia for Optimization of Cardiovascular Risk (PAPVASC)
Status: TERMINATED
Conditions: Preeclampsia Severe|Cardiovascular Diseases|Primary Prevention
Interventions: DRUG: Low-dose aspirin|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study of the Safety and Effectiveness of an Investigational Cell Therapy Given With and Without an Investigational RNA-based Vaccine in Patients With Organ Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: BIOLOGICAL: CLDN6 CAR-T|BIOLOGICAL: CLDN6 uRNA-LPX/CLDN6 modRNA-LPX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weekly Paclitaxel/Carboplatin With Neupogen in Gynaecological Cancers
Status: COMPLETED
Conditions: Ovarian Cancer|Endometrial Cancer|Uterine Cervical Cancer
Interventions: DRUG: Filgrastim|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Extension Study Designed to Assess Effects of Losartan on Proteinuria in Pediatric Populations (MK-0954-326 AM1,EXT1(AM2))
Status: COMPLETED
Conditions: Proteinuria
Interventions: DRUG: Losartan Potassium|OTHER: Comparator: Placebo (Losartan)|DRUG: Comparator: amlodipine besylate|OTHER: Comparator: Placebo (amlodipine besylate)|OTHER: Placebo (Losartan)|DRUG: Enalapril Maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Musculotendinous Tissue Unit Repair and Reinforcement (MTURR) Coordinating Center
Status: WITHDRAWN
Conditions: Traumatic Injury|Muscle Injury|Tendon Injury|Soft Tissue Injury|Extremity Injury
Interventions: DEVICE: Extracellular Matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ceftibuten/VNRX-7145 in Participants With Varying Degrees of Renal Function
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: VNRX-7145|DRUG: Ceftibuten
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Wound Closure Using V-Loc™ 90 Sutures in Lipoabdominoplasty Patients
Status: UNKNOWN
Conditions: Open Surgical Wounds
Interventions: DEVICE: conventional closure|DEVICE: V-Loc 90
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Chemotherapy With Adriamycin/Cyclophosphamide(AC) vs Taxotere/Xeloda(TX) for Stage II and III Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Anthracycline, Cyclophosphamide, Docetaxel, Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calcific Tendonitis Treatment: Barbotage vs. Barbotage With Cortisone Injection
Status: TERMINATED
Conditions: Calcific Tendinitis
Interventions: DRUG: Barbotage|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Repositioning and Cranial Remolding in Infants With Cranial Deformation
Status: RECRUITING
Conditions: Deformational Plagiocephaly|Deformational Posterior Plagiocephaly|Brachycephaly|Torticollis|Congenital Muscular Torticollis
Interventions: OTHER: Repositioning Therapy|DEVICE: Cranial Remolding Orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IV Dexmedetomidine vs Oral Gabapentin and Their Combination for Postoperative Analgesia in Cancer Patients Undergoing Modified Radical Mastectomy
Status: COMPLETED
Conditions: Breast Cancer|Pain, Postoperative|Pain, Acute
Interventions: DRUG: Dexmedetomidine Hydrochloride 0.5 MG/ML|DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intratonsillar Immunotherapy for Allergic Rhinitis
Status: RECRUITING
Conditions: Allergic Rhinitis
Interventions: PROCEDURE: Intratonsillar immunotherapy (ITIT)|PROCEDURE: Subcutaneous immunotherapy (SCIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0812 High Dose Cholecalciferol in Premenopausal Women at High-Risk for Breast Cancer
Status: COMPLETED
Conditions: brca1 Mutation Carrier|brca2 Mutation Carrier|Breast Cancer
Interventions: DIETARY_SUPPLEMENT: cholecalciferol|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Treatment of Postherpetic Neuralgia in the Head and Face With Superficial Needling Combined With Electroacupuncture
Status: RECRUITING
Conditions: Postherpetic Neuralgia|Electroacupuncture|Infrared Thermography
Interventions: OTHER: electroacupuncture|DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemithoracic Irradiation With Proton Therapy in Malignant Pleural Mesothelioma
Status: RECRUITING
Conditions: Malignant Pleural Mesothelioma
Interventions: RADIATION: Proton beam therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Switching From Zidovudine to an NNRTI or Lopinavir/Ritonavir in Patients Treated With Zidovudine/ Lamivudine/Abacavir.
Status: COMPLETED
Conditions: HIV Associated Lipodystrophy Syndrome.|HIV|Hypercholesterolemia|Lipoatrophy
Interventions: DRUG: Different HAART regimens
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting INflammation Using SALsalate in Type 2 Diabetes (TINSAL-T2D)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Salsalate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Block and Quadratus Lumborum Block in Pediatric Patients
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Tramadol hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: STITCH2 (Simplified Therapeutic Intervention to Control Hypertension and Hypercholesterolemia)
Status: COMPLETED
Conditions: Hypertension|Hypercholesterolemia
Interventions: OTHER: Treatment algorithm:caduet, Amlodipine, ACEI-ARB combo dose, a-blocker, b-blocker or spironolactone, dyslipidemic therapy with ezetamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Gastrografin to Help Alleviate Bowel Obstruction in Gastroschisis Patients.
Status: WITHDRAWN
Conditions: Gastroschisis|Bowel Obstruction|Birth Defect
Interventions: DRUG: Gastrografin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant FOLFOX6 + Cetuximab in Patients With Colorectal Cancer and Unresectable Liver Metastasis
Status: COMPLETED
Conditions: Colorectal Cancer|Unresectable Liver Metastasis
Interventions: DRUG: FOLFOX6/cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CHICAMOCHA 3 - Equivalence of Usual Interventions for Trypanosomiasis (EQUITY)
Status: UNKNOWN
Conditions: Chagas Disease
Interventions: DRUG: Nifurtimox|DRUG: Benznidazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn if the Study Medicines Called Itraconazole and Cyclosporine Change How the Body Processes the Other Study Medicine Called Danuglipron in Healthy Adults.
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: Danuglipron|DRUG: Cyclosporine|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-GPC3 CAR T for Recurrent or Refractory Lung Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Lung Squamous Cell Carcinoma
Interventions: GENETIC: CAR-GPC3 T Cells|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endovascular Procedures With Computer Assistance in the Chronic Occlusive Arthritis of the Lower Limbs on the Femoro-popliteal Stage.
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: PROCEDURE: Creation of a bone and arterial panorama using EndoNaut® software.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Translating Evidence-based Interventions for ASD: Multi-Level Implementation Strategy
Status: ENROLLING_BY_INVITATION
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Teams Leadership Institute (TLI)|BEHAVIORAL: Motivational Enhancement (TIPS for Training)|BEHAVIORAL: Classroom Pivotal Response Teaching (CPRT)|BEHAVIORAL: An Individualized Mental Health Intervention for ASD (AIM HI)|BEHAVIORAL: Team-Enhanced Teams Leadership Institute (TLI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Clinical Effect of Monodisperse Fluticasone Propionate in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: 1.5 microns at 50mg|DRUG: 6 microns at 50mg|DRUG: Placebo Comparator|DRUG: MDI FP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to DEN4 Vaccine Component Candidate for Dengue Virus
Status: COMPLETED
Conditions: Dengue Shock Syndrome|Dengue Hemorrhagic Fever
Interventions: BIOLOGICAL: DEN4 Vaccine Candidate|BIOLOGICAL: DEN4 Vaccine Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Melatonin on Reperfusion Injury
Status: UNKNOWN
Conditions: Reperfusion Injury, Myocardial
Interventions: DRUG: melatonin (Helsinn Chemical Co, Biasca, Switzerland)|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Patients With Nocturia (Non-PK Study)
Status: COMPLETED
Conditions: Nocturia
Interventions: DRUG: SER120|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Family Caregivers in Underserved Populations Providing Complex Cancer Care
Status: COMPLETED
Conditions: Malignant Female Reproductive System Neoplasm|Stage 0 Lung Cancer AJCC v8|Stage I Lung Cancer AJCC v8|Stage IA1 Lung Cancer AJCC v8|Stage IA2 Lung Cancer AJCC v8|Stage IA3 Lung Cancer AJCC v8|Stage IB Lung Cancer AJCC v8|Stage II Lung Cancer AJCC v8|Stage IIA Lung Cancer AJCC v8|Stage IIB Lung Cancer AJCC v8|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: OTHER: Educational Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of T-2345 Compared to Xalatan in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: T-2345|DRUG: Xalatan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Interest of LUMEEN Virtual Reality Headset to Reduce Preoperative Anxiety in AMBulatory Surgery
Status: COMPLETED
Conditions: Anxiety
Interventions: DEVICE: Virtual reality session|OTHER: State Trait Anxiety Inventory|OTHER: Virtual Reality Satisfaction Score|OTHER: Perioperative care satisfaction score
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrahepatic and Peripheral Responses to Imdusiran (AB-729) in Chronic Hepatitis B
Status: RECRUITING
Conditions: Chronic Hepatitis B
Interventions: DRUG: Imdusiran (AB-729)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Enzalutamide and Niclosamide in Treating Patients With Recurrent or Metastatic Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Prostate Carcinoma|Recurrent Prostate Carcinoma|Stage IV Prostate Cancer
Interventions: DRUG: Enzalutamide|DRUG: Niclosamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HYDROxychloroquine in Syndrome Primary AntiPhospholipid
Status: RECRUITING
Conditions: Antiphospholipid Syndrome in Pregnancy|Anticoagulants
Interventions: DRUG: Plaquenil 200Mg Tablet|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcranial Direct Current Stimulation (tDCS) on Brain Organization and Naming in Aphasic Patients.
Status: RECRUITING
Conditions: Stroke|Aphasia
Interventions: DEVICE: HD-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Premature Rupture Membranes and tPTL: a Personalised Approach (PROMPT)
Status: NOT_YET_RECRUITING
Conditions: Preterm Rupture of Membranes|Threatened Preterm Labor
Interventions: DIAGNOSTIC_TEST: Amniocentesis|OTHER: Routine care without amniocentesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen, Neutrophil-oxidative Burst, and Cytokines
Status: UNKNOWN
Conditions: Infection
Interventions: DRUG: Hyperbaric Oxygen|OTHER: Hyperbaric Air/Oxygen|OTHER: Normobaric oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multi-national, Safety and Performance Study of New Ostomy Product Compared to Standard Care
Status: TERMINATED
Conditions: Leakage|Skin Condition
Interventions: DEVICE: New ostomy base plate (SS)|DEVICE: Standard Care base plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucomannan for Childhood Functional Constipation.
Status: COMPLETED
Conditions: Functional Constipation
Interventions: DIETARY_SUPPLEMENT: Glucomannan|DIETARY_SUPPLEMENT: maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Tenalisib (RP6530), a Novel PI3K δ/γ Dual Inhibitor in Patients With Relapsed/Refractory Indolent Non-Hodgkin's Lymphoma (iNHL)
Status: COMPLETED
Conditions: Non Hodgkin Lymphoma
Interventions: DRUG: Tenalisib,
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corticosteroids + Bevacizumab vs. Corticosteroids + Placebo (BEST) for Radionecrosis After Radiosurgery for Brain Metastases
Status: TERMINATED
Conditions: Radionecrosis|Brain Metastases
Interventions: DRUG: bevacizumab|DRUG: corticosteroids|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long-term Follow-up Study of Allogeneic Gamma Delta (γδ) CAR T Cells
Status: ENROLLING_BY_INVITATION
Conditions: Lymphoma, Follicular|Lymphoma, Mantle-Cell|Marginal Zone Lymphoma|Primary Mediastinal B-cell Lymphoma|Diffuse Large B Cell Lymphoma|Lymphoma, Non-Hodgkin
Interventions: GENETIC: ADI-001
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: New Onset of Type 1 Diabetes Mycophenolate Mofetil-Daclizumab Clinical Trial
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Mycophenolate mofeteil (MMF)|DRUG: Daclizumab (DZB)|DRUG: Placebo control for Mycophenolate mofeteil (MMF)|DRUG: Placebo control for Daclizumab (DZB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety and Effectiveness of the HIT Reverse HRS
Status: RECRUITING
Conditions: Degenerative Joint Disease|Osteoarthritis, Hip|Avascular Necrosis of Hip|Traumatic Arthropathy-Hip
Interventions: DEVICE: Hip Innovation Technology Reverse Hip Replacement System|DEVICE: Already-marketed semi-constrained uncemented hip systems using a metal-on-XLPE or ceramic-on-XLPE bearing combination.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhaled Sodium Nitrite on Heart Failure With Preserved Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Sodium Nitrite Inhalation Solution|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Assess the Short- and Long-term Efficacy of Certolizumab Pegol Plus Methotrexate Compared to Adalimumab Plus Methotrexate in Subjects With Moderate to Severe Rheumatoid Arthritis (RA) Inadequately Responding to Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Certolizumab Pegol (CZP)|BIOLOGICAL: Adalimumab (ADA)|DRUG: Methotrexate (MTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Long-Term Safety of Budesonide for Patients With Chronic Rhinosinusitis
Status: UNKNOWN
Conditions: Sinusitis
Interventions: DEVICE: Budesonide via MAD device|DEVICE: Budesonide via intranasals Saline Irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study on the Efficacy of 10 mg Oral Mifepristone for the Treatment of Symptomatic Uterine Leiomyomas
Status: TERMINATED
Conditions: Leiomyoma
Interventions: DRUG: mifepristone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine and Oxaliplatin in Patients With Advanced or Metastatic Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Prosthesis for Comminuted Fracture of Lateral Half of Clavicle
Status: COMPLETED
Conditions: Bone Fracture|Bone Lesion|Clavicle Fracture
Interventions: PROCEDURE: Surgery to fix lateral half prosthesis for clavicle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pilot Trial of Resistant Starch in Stage I-III Colorectal Cancer Survivors
Status: TERMINATED
Conditions: Colon Cancer|Rectal Cancer|Cancer Survivor|Colorectal Adenocarcinoma|Stage I Colorectal Cancer AJCC v8|Stage II Colorectal Cancer AJCC v8|Stage IIA Colorectal Cancer AJCC v8|Stage IIB Colorectal Cancer AJCC v8|Stage IIC Colorectal Cancer AJCC v8|Stage III Colorectal Cancer AJCC v8|Stage IIIA Colorectal Cancer AJCC v8|Stage IIIB Colorectal Cancer AJCC v8|Stage IIIC Colorectal Cancer AJCC v8
Interventions: OTHER: Dietary Intervention (resistant starch)|OTHER: Dietary Intervention (regular starch)|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Safety, Tolerability, Efficacy and PK of APL-2 in Patients With Warm Type Autoimmune Hemolytic Anemia (wAIHA) or Cold Agglutinin Disease (CAD)
Status: COMPLETED
Conditions: Warm Autoimmune Hemolytic Anemia|Cold Agglutinin Disease
Interventions: DRUG: APL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of UX007 (Triheptanoin) in Participants With Long-Chain Fatty Acid Oxidation Disorders (LC-FAOD)
Status: COMPLETED
Conditions: Long-chain Fatty Acid Oxidation Disorders (LC-FAOD)|Carnitine Palmitoyltransferase (CPT II) Deficiency|Very Long Chain Acyl-CoA Dehydrogenase (VLCAD) Deficiency|Longchain 3-hydroxy-acyl-CoA Dehydrogenase (LCHAD) Deficiency|Trifunctional Protein (TFP) Deficiency
Interventions: DRUG: UX007
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Use of Cellular Matrix/ A-CP-HA Kit
Status: RECRUITING
Conditions: Genitourinary Syndrome of Menopause
Interventions: DRUG: Cellular Matrix / A-CP-HA Kit|DRUG: Local estrogen therapy (Blissel, estriol 50 micrograms/g vaginal gel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-inflammatory Pulmonal Therapy of Cystic Fibrosis (CF) Patients With Amitriptyline and Placebo
Status: UNKNOWN
Conditions: Cystic Fibrosis|Pneumonia
Interventions: DRUG: Amitriptyline|DRUG: Mannite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preliminary Clinical Study of NMN Intervention in Mild Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis Chronic Mild
Interventions: DIETARY_SUPPLEMENT: nicotinamide mononucleotide|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can Supplemental Leucine Offset Disuse-induced Muscle Atrophy?
Status: COMPLETED
Conditions: Muscle Disuse Atrophy
Interventions: DIETARY_SUPPLEMENT: Leucine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Radiation Therapy After Surgery in People With Oral Tongue Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Oral Tongue Squamous Cell Carcinoma
Interventions: RADIATION: Photon intensity modulated radiation therapy (IMRT)|OTHER: Life questionnaire's
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Zegerid on Esophageal pH in Patients With Barrett's Esophagus
Status: TERMINATED
Conditions: Barrett Esophagus|Gastroesophageal Reflux
Interventions: DRUG: Zegerid (proton pump inhibitor)|PROCEDURE: Bravo pH monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-ranging Study of Dentoxol® Mouthrinse for Managing Oral Symptoms in People With Epidermolysis Bullosa.
Status: UNKNOWN
Conditions: Epidermolysis Bullosa|Oral Ulcer
Interventions: COMBINATION_PRODUCT: Dentoxol mouthrinse dosages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: IcoSApent ethyL to Slow Down Aortic VAlve Stenosis proGrEssion
Status: RECRUITING
Conditions: Aortic Valve Stenosis
Interventions: DRUG: Icosapent ethyl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Omega-3 Hypertension Trial (VITAL Hypertension)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: Vitamin D-3 (cholecalciferol), 2000 IU|DRUG: Omega-3 fatty acids (fish oil)|DIETARY_SUPPLEMENT: Vitamin D placebo|DRUG: Fish oil placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effectiveness of MEDI-563 in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: OTHER: Placebo|BIOLOGICAL: Benralizumab 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Complementary Food Supplement on Growth and Morbidity of Ghanaian Infants
Status: COMPLETED
Conditions: Growth Disorders|Infant Malnutrition|Micronutrient Deficiency|Protein Malnutrition|Morbidity;Infant
Interventions: DIETARY_SUPPLEMENT: Macro-micronutrient complementary food supplement|DIETARY_SUPPLEMENT: A micronutrient powder|BEHAVIORAL: Nutrition education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Electroencephalography Study Investigating the Effects of Vortioxetine in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Men
Interventions: DRUG: Vortioxetine 10 mg|DRUG: Vortioxetine 20 mg|DRUG: Escitalopram 15 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Khushi Baby (KB): Novel Mobile Health Solution for Vaccination Record Keeping in India
Status: UNKNOWN
Conditions: DTP Vaccine Series Completion
Interventions: DEVICE: NFC Necklace|DEVICE: Voice Reminder|DEVICE: NFC Sticker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Isolation of Circulating Pulmonary Cells in COPD and Its Relationship With Clinical Relevant Outcomes (IbICEnCa)
Status: UNKNOWN
Conditions: COPD|COPD Exacerbation|COPD, Severe Early-Onset
Interventions: DIAGNOSTIC_TEST: Isolation of Circulating Pulmonary Cells in peripheral blood
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Novel MRI Quantification Free Breathing Technique in Evaluation of Liver Lesions
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: liver biopsy|DEVICE: free-breathing MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mobile Applet for Weight Management in Obese Heart Failure Patients
Status: NOT_YET_RECRUITING
Conditions: Heart Failure|Overweight and Obesity|Weight Loss|Heart Failure With Reduced Ejection Fraction
Interventions: BEHAVIORAL: Full usage of diet management app group and with the full usage of an intelligent weight scale|BEHAVIORAL: Limited usage of diet management app group and with the limited usage of an intelligent weight scale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Influence of Morphine on Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients With Acute Myocardial Infarction
Status: COMPLETED
Conditions: ST-segment Elevation Myocardial Infarction|Non-ST-segment Elevation Myocardial Infarction|VA Drug Interactions
Interventions: DRUG: Morphine|DRUG: Placebo|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of PH-10 Aqueous Hydrogel for the Treatment of Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: PH-10 (0.001% Rose Bengal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation Into the Effects of Krill Oil vs. Fish Oil on Markers of Cardiovascular Disease
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Krill oil|DIETARY_SUPPLEMENT: Fish oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of Endobronchial Valves in Non-Upper Lobe Heterogeneous Emphysema
Status: COMPLETED
Conditions: Heterogeneous Emphysema
Interventions: DEVICE: Intra-bronchial valve (Spiration IBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three-dimensional Optical Surface Imaging as a Diagnostic Tool in Pectus Excavatum
Status: UNKNOWN
Conditions: Pectus Excavatum
Interventions: OTHER: 3D optical surface image|RADIATION: Chest radiography|RADIATION: CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Patiromer to Transition Chronic Kidney Disease Patients With Hyperkalemia to a Plant-rich Diet.
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Hyperkalemia
Interventions: DRUG: Patiromer|DIETARY_SUPPLEMENT: Research Diet Menu
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arginine Therapy in Sickle Cell Disease-VOC Clinical Trial
Status: COMPLETED
Conditions: Vaso-occlusive Pain Episodes
Interventions: DRUG: Arginine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FGF-1 for Topical Administration for the Treatment of Diabetic or Venous Stasis Ulcers
Status: COMPLETED
Conditions: Chronic Wounds|Diabetes|Venous Stasis Ulcers
Interventions: DRUG: FGF-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Provided by a Physiotherapy Treatment Preventing Lower Extremity Injuries in Female Football Players
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Injuries|Injuries, Knee|Prevention & Control
Interventions: BEHAVIORAL: Physiotherapy program of lumbopelvic stabilization and strengthening of the hip region musculature
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability of Regeneron Anti-SARS-CoV-2 Monoclonal Antibody/Ies in Adult Healthy Volunteers as Related to COVID-19
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: REGN15160 (IV)|DRUG: Matching Placebo (IV)|DRUG: REGN15160 (SC)|DRUG: Matching Placebo (SC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Train the Brain - Cognitive and Physical Training for Slowing Dementia
Status: UNKNOWN
Conditions: Mild Cognitive Impairment|Dementia|Memory Disorders
Interventions: BEHAVIORAL: Cognitive and Physical training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized Study To Evaluate The Efficacy And Safety Of An Investigational Drug In Adolescent And Adult Subjects With Asthma Uncontrolled on Low-Dose ICS Therapy.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: GW685698X|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Intramuscular Olanzapine Depot With Placebo in the Treatment of Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Intramuscular Olanzapine Depot|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability, and Reactogenicity of an RBD-Fc-based Vaccine to Prevent COVID-19
Status: COMPLETED
Conditions: Coronavirus
Interventions: BIOLOGICAL: Baiya SARS-CoV-2 Vax 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Digital Implementation Support to Achieve Uptake and Integration of Task-Shared Care for Schizophrenia in Primary Care in India
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia|Schizophrenia and Related Disorders|Psychosocial Functioning
Interventions: BEHAVIORAL: Community care for People with Schizophrenia in India (COPSI)|BEHAVIORAL: mindLAMP Mobile Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Gait in Syndesmosis Injuries Treated With Screw Fixation vs Suture Button
Status: RECRUITING
Conditions: Acute Disruption of Ankle Syndesmosis
Interventions: DEVICE: Suture Button vs Screw Fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ganglion Plexus Ablation in Persistent Atrial Fibrillation
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation, Persistent|Ganglionated Plexi|Catheter Ablation
Interventions: PROCEDURE: ganglionated plexus ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Metagenomic and Metatranscriptomic Analysis of Clinical Plaque Samples
Status: COMPLETED
Conditions: Plaque
Interventions: DRUG: Colgate Maximum Cavity Protection plus Sugar Acid Neutralizer|DRUG: Colgate Cavity Protection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Taurine on Morbidity and Mortality in the Elderly Hip Fracture Patient
Status: COMPLETED
Conditions: Insulin Resistance|Elderly Patient|Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: taurine|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Addition of Anlotinib Hydrochloride to the Stupp Regimen Versus the Stupp Regimen Alone for Newly Diagnosed Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: Anlotinib Hydrochloride|RADIATION: Radiation therapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Coronary Artery Lesion Using Optical Coherence Tomography Versus IntraVascular Ultrasound for BiorEsorbable Vascular Scaffold Implantation
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: OTHER: Optical coherent tomography|OTHER: IntraVascular UltraSound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Carbon Dioxide (CO2) and Cognitive Impairment
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: 2500 ppm Carbon Dioxide|OTHER: 600 ppm Carbon Dioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE