pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Adherence to the Transition-discharge-hospital Plan in Patient-family Caregiver With Chronic Pathology
Status: UNKNOWN
Conditions: Treatment Adherence and Compliance
Interventions: BEHAVIORAL: The intervention with the patient (Chronic Patient Care Group and his family.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The PrEP (Pre-exposure Prophylaxis) SMART Study
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: BEHAVIORAL: WhatsApp Group|BEHAVIORAL: 2-way SMS|BEHAVIORAL: Drug level feedback|BEHAVIORAL: Monthly counseling sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prognosis Study of Different Anterior Cruciate Ligament Surgery Methods
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Injuries
Interventions: PROCEDURE: Anatomical single-bundle reconstruction（ASBR method）|PROCEDURE: Double-bundle reconstruction （DBR method）|PROCEDURE: Central axial single-bundle reconstruction（CASBR group）|OTHER: rehabilitation training protocol|OTHER: Educate patients on return to sports and the importance of quadriceps strength
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Telehealth Based Synchronous Navigation to Improve Molecularly-Informed Care for Patients With Lung Cancer
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: OTHER: Telehealth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pharmacokinetic Study of Diazoxide Choline in Hypertriglyeridemic Subjects
Status: COMPLETED
Conditions: Hypertriglyceridmia
Interventions: DRUG: Diazoxide Choline Controlled-Release Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Cediranib Maleate in Treating Patients With Recurrent or Metastatic Kidney Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Recurrent Renal Cell Carcinoma|Stage IV Renal Cell Cancer
Interventions: DRUG: Cediranib Maleate|PROCEDURE: Dynamic Contrast-Enhanced Magnetic Resonance Imaging|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PREVENT-COVID-19: A Q-Griffithsin Intranasal Spray
Status: COMPLETED
Conditions: COVID-19 Prevention
Interventions: DRUG: Q-Griffithsin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Electrolysis Technique vs Manual Therapy in Pelvic Pain
Status: COMPLETED
Conditions: Dyspareunia|Pelvic Pain|Pelvic Floor Disorders|Musculoskeletal Pain|Perineal Tear
Interventions: PROCEDURE: Pelvic floor manual therapy group|PROCEDURE: Pelvic floor electrolysis group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Flow Nasal Oxygen Therapy in Perioperative Period of the Adult With Hypercapnic and Hypoxemic Respiratory Faliure
Status: UNKNOWN
Conditions: Acute Respiratory Failure With Hypercapnia
Interventions: OTHER: standard low flow therapy|DEVICE: high flow nasal oxygen therapy|DEVICE: association of high flow nasal oxygen therapy and non invasive positive pressure ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corneal Nerves Function and Structure
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Peripheral Neuropathy
Interventions: DIETARY_SUPPLEMENT: Blackmores Omega Daily (4 1g capsules per day)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical and Therapeutic Implications of Fibrosis in Hypertrophic Cardiomyopathy
Status: COMPLETED
Conditions: Myocardial Fibrosis|Hypertrophic Cardiomyopathy
Interventions: DRUG: Spironolactone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Dose of Succinylcholine and Rocuronium for Electroconvulsive Therapy (ECT)
Status: COMPLETED
Conditions: Neuromuscular Blockade|ECT
Interventions: DRUG: Succinylcholine|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acarbose Cardiovascular Evaluation Trial
Status: COMPLETED
Conditions: Coronary Heart Disease|Acute Coronary Syndrome|Impaired Glucose Tolerance|Type 2 Diabetes Mellitus (T2DM)
Interventions: DRUG: Acarbose|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Relief Band as an Adjunct to Antiemetic Therapy in Patients Who Receive Mod to Highly Emetogenic Chemotherapy
Status: WITHDRAWN
Conditions: Nausea|Vomiting
Interventions: DEVICE: Activated Nometex Device|DEVICE: Unactivated Nometex Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anticoagulation in AF Ablation and Effects on Neurocognitive Function
Status: WITHDRAWN
Conditions: Atrial Fibrillation|Cerebrothromboembolus|Neurocognitive Function
Interventions: PROCEDURE: Atrial Fibrillation Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avelumab With Chemoradiation in Locally Advanced Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DRUG: Avelumab|DRUG: 5 Fluorouracil|DRUG: Capecitabine Pill|RADIATION: Radiotherapy|PROCEDURE: Surgical Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Trimethoprim/Sulfamethoxazole to Prevent Severe Infections in Patients With Lupus Erythematous
Status: UNKNOWN
Conditions: Lupus Erythematosus, Systemic
Interventions: DRUG: Trimethoprim-Sulfamethoxazole|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Choose It and Use It: Choice, Implementation Intentions and At-Home Colorectal Cancer Screening
Status: ENROLLING_BY_INVITATION
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Usual Care Message|BEHAVIORAL: Implementation Intention Intervention: Standard Message|BEHAVIORAL: Implementation Intention Intervention: Culturally-Targeted Message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Pembrolizumab and Ibrutinib in Treating Patients with Stage III-IV Melanoma That Cannot Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Melanoma|Stage III Cutaneous Melanoma AJCC V7|Stage IIIA Cutaneous Melanoma AJCC V7|Stage IIIB Cutaneous Melanoma AJCC V7|Stage IIIC Cutaneous Melanoma AJCC V7|Stage IV Cutaneous Melanoma AJCC V6 and V7|Unresectable Melanoma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Muscle Training X CardioBreath App Effects On Vagal Modulation And Pulse Wave Velocity
Status: RECRUITING
Conditions: Postmenopausal Disorder|Autonomic Imbalance|Vascular Stiffness
Interventions: DEVICE: CardioBreathApp|DEVICE: IMT PowerBreath|DEVICE: IMT PowerBreath Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Comparing The Amounts of Tafamidis In The Blood With Or Without Food
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: tafamidis|DRUG: tafamidis|DRUG: tafamidis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Prebiotic Synergy1 Supplementation on Microbiota, Protein Metabolism and Gastrointestinal (GI) Symptoms in People Consuming High Protein Diet
Status: COMPLETED
Conditions: Gut Microbiota
Interventions: DIETARY_SUPPLEMENT: Synergy1|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transporter Mediated Uptake of Montelukast
Status: COMPLETED
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: Grapefruit juice|DIETARY_SUPPLEMENT: Orange Juice|DIETARY_SUPPLEMENT: Gatorade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: BIBF 1120 + Docetaxel (Japan) in Patients With Advanced Non-small-cell Lung Cancer, Phase I
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: BIBF 1120 M + docetaxel M|DRUG: BIBF 1120 M + docetaxel H|DRUG: BIBF 1120 H + docetaxel H|DRUG: BIBF 1120 L + docetaxel M|DRUG: BIBF 1120 H + docetaxel M
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study of MRA in Patient With Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: MRA(Tocilizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging Techniques to Monitor Photosensitizer and sO2 Levels During Photodynamic Therapy of Actinic Keratoses
Status: NOT_YET_RECRUITING
Conditions: Actinic Keratoses
Interventions: DRUG: Topical Aminolevulinate|PROCEDURE: Photodynamic therapy (PDT)|PROCEDURE: Red light illumination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Surfactant for Neonatal Respiratory Distress Syndrome(NRDS) and Neonatal Acute Respiratory Distress Syndrome(NARDS)
Status: RECRUITING
Conditions: Respiratory Distress Syndrome|Preterm Birth|Acute Respiratory Distress Syndrome|Surfactant Dysfunction
Interventions: DRUG: one dose of surfactant replacement|DRUG: two and more doses of surfactant replacement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MENOPUR® Versus FOLLISTIM®
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Menotropin|DRUG: Progestrone vaginal insert|DRUG: follitropin beta|DRUG: Progesterone in oil|DRUG: Ganirelix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PMCF Study to Evaluate Performance and Safety of "Hyaluronic Acid (HA)-Based Eyedrops" Used to Relieve Dry Eye Symptoms
Status: COMPLETED
Conditions: Dry Eye|Dry Eye Disease|Kerato Conjunctivitis Sicca
Interventions: DEVICE: Hyaluronic acid eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Randomized, Parallel-controlled Clinical Trial Protocol to Validate the Safety and Efficacy of a Steep Pulse Therapy System for the Treatment of Liver Tumors
Status: UNKNOWN
Conditions: A Steep Pulse Therapy System for the Treatment of Liver Tumors
Interventions: DEVICE: steep pulse therapy system|DEVICE: RF Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PENG vs. FIC Blocks in Hip Fractures in the ED
Status: NOT_YET_RECRUITING
Conditions: Hip Fractures|Nerve Block|Analgesia
Interventions: PROCEDURE: Pericapsular Nerve Group (PENG) Block|PROCEDURE: Fascia Iliaca Compartment (FIC) Block for Patients with Isolated Hip Fractures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Vernakalant Hydrochloride (MK-6621) in Patients With Atrial Fibrillation (MK-6621-010 AM4)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: vernakalant hydrochloride|DRUG: Placebo to vernakalent hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Abatacept for the Treatment of Relapsing, Non-Severe, Granulomatosis With Polyangiitis (Wegener's)
Status: COMPLETED
Conditions: Granulomatosis With Polyangiitis (Wegener's)|Granulomatosis With Polyangiitis|Wegener's Granulomatosis|ANCA-Associated Vasculitis
Interventions: DRUG: Abatacept|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Duvelisib and Nivolumab for the Treatment of Stage IIB-IVB Mycosis Fungoides and Sezary Syndrome
Status: RECRUITING
Conditions: Stage IIB Mycosis Fungoides and Sezary Syndrome AJCC v8|Stage III Mycosis Fungoides and Sezary Syndrome AJCC v8|Stage IV Mycosis Fungoides and Sezary Syndrome AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Duvelisib|BIOLOGICAL: Nivolumab|PROCEDURE: Positron Emission Tomography|PROCEDURE: Punch Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estramustine, Etoposide and Paclitaxel Treatment for Hormonally Responsive Adenocarcinoma of the Prostate
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Estramustine|DRUG: Etoposide|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Long-term Consumption of Full-fat Dairy Products on Satiety, Body Weight and Glycemic Control
Status: ACTIVE_NOT_RECRUITING
Conditions: Overweight or Obesity|Body Weight
Interventions: OTHER: Dairy-based commercially available food products|OTHER: Restrictive Eating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomised Multi-centre Trial Comparing cArdiac MRI Guided CRT Versus Conventional CRT Implantation in Patients With Ischaemic Cardiomyopathy
Status: RECRUITING
Conditions: Cardiovascular Diseases
Interventions: DEVICE: Guide CRT Software Prototype
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Continue or Stop Applying Wet Cupping (Al-Hijamah) in Migraine
Status: COMPLETED
Conditions: Migraine Disorders|Migraine With Aura|Migraine Without Aura
Interventions: PROCEDURE: Wet Cupping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomechanically Compatible,Minimally Invasive Technique for Recurrence Free Groin Hernia Repair
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: DEVICE: Wing shaped Tensiflex prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of AVE5026 as Compared to Enoxaparin for the Prevention of Thromboembolism in Patients Undergoing Hip Fracture Surgery
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Enoxaparin sodium|DRUG: Semuloparin sodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SCP Hip Outcomes Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Subchondral Cysts|Subchondral Bone Edema|Bone Marrow Edema|Insufficiency Fractures|Avascular Necrosis of Hip|Femoroacetabular Impingement|Dysplasia; Hip
Interventions: DEVICE: Subchondroplasty Procedure with AccuFill
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Collection of Vital Status and Pulmonary Medication Usage Data for Patients With Chronic Obstructive Pulmonary Disease (COPD) Who Withdrew Prematurely From Tiotropium Inhalation Solution Delivered by the Respimat Inhaler
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study for Evaluation of Cryobiopsy and Correlation With Standard Forceps Biopsy
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastrointestinal Disease
Interventions: DEVICE: Cryobiopsy probe, administered to study participants
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Study to Evaluate KER-050 as a Monotherapy or in Combination With Ruxolitinib in Myelofibrosis
Status: RECRUITING
Conditions: Myelofibrosis
Interventions: DRUG: KER-050 monotherapy|DRUG: KER-050 in combination with ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Placebo Versus Enzastaurin for Lung Cancer Prevention in Former Smokers
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Enzastaurin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of a Combination Drug Product for Treatment of Short-term Insomnia
Status: COMPLETED
Conditions: Short-term Insomnia
Interventions: DRUG: SM-1|DRUG: Comparator|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compression Treatment Effects on Complications and Healing of Achilles Tendon Rupture
Status: COMPLETED
Conditions: Rupture|Venous Thromboembolism|Venous Thrombosis|Surgical Wound Infection
Interventions: DEVICE: Intermittent pneumatic compression (IPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Isolated Hepatic Perfusion With Melphalan Followed By Chemotherapy in Treating Patients With Unresectable Colorectal Cancer That is Metastatic to the Liver
Status: COMPLETED
Conditions: Recurrent Colon Cancer|Liver Metastases|Stage IV Rectal Cancer|Recurrent Rectal Cancer|Stage IV Colon Cancer
Interventions: DRUG: floxuridine|DRUG: leucovorin calcium|DRUG: melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells for Treatment of Refractory Chronic Graft-versus-host Disease
Status: UNKNOWN
Conditions: Chronic Graft-versus-host Disease
Interventions: BIOLOGICAL: Mesenchymal stem cells|BIOLOGICAL: Non-mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Retinal Non-perfusion in Central Retinal Vein Occlusion by Hydroxycarbamide Treatment.
Status: UNKNOWN
Conditions: Central Retinal Vein Occlusion, Non-Ischemic
Interventions: DRUG: Hydroxycarbamid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Emotional Freedom Technique on Students
Status: UNKNOWN
Conditions: Coping Skills|Anxiety|Complementary Therapies|Stress
Interventions: OTHER: Complementary Therapies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Potential of Oxytocin to Reduce Opioid Abuse Liability and Pain Among Older Adults
Status: RECRUITING
Conditions: Pain
Interventions: DRUG: OxyCODONE 5 mg Oral Tablet|DRUG: OxyCODONE 2.5 mg Oral Tablet|OTHER: Placebo oxyCODONE Oral Tablet|DRUG: Oxytocin Nasal Spray (48 IU)|OTHER: Placebo Oxytocin Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Perioperative Challenges: Does Smoking Compromise High-Flow Nasal Oxygen Efficacy in Obese Men?
Status: RECRUITING
Conditions: Obese
Interventions: DEVICE: apnoeic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Coronary and Structural Interventions Ulm - Transcatheter Mitral Valve Repair (CSI-Ulm-TMVR)
Status: COMPLETED
Conditions: Mitral Valve Regurgitation
Interventions: DEVICE: CE certified mitral valve repair systems
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Changes in End Expiratory Lung Impedence Measured by EIT and End Expiratory Lung Volume Measured by Passive Expiratory in Controlled Mechanical Ventilated Exacerbation COPD Patients
Status: RECRUITING
Conditions: COPD
Interventions: DIAGNOSTIC_TEST: the changes of end expiratory lung impedence|DIAGNOSTIC_TEST: the changes of end expiratory lung volume
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of BIA 5-1058 400 mg on the Steady State Pharmacokinetics of Sildenafil
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: BIA 5-1058|DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Randomized Double-Blind Placebo-Controlled Study To Investigate the Effect of Isoprinosine in Patients With AIDS Related Complex (ARC)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Inosine pranobex
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase 2/3, Randomized, Double-Masked, Sham-Controlled Trial of QPI-1007 in Subjects With Acute Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)
Status: TERMINATED
Conditions: Non Arteritic Anterior Ischemic Optic Neuropathy
Interventions: DRUG: QPI-1007 Injection - 1.5 mg|DRUG: QPI-1007 Injection - 3.0 mg|OTHER: Sham Injection Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Lycium Barbarum Supplements on the Progression of Senile Cataract in Hong Kong Chinese Population
Status: COMPLETED
Conditions: Lens Opacity
Interventions: DIETARY_SUPPLEMENT: Starch|DIETARY_SUPPLEMENT: Lycium Barbarum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Complement Inhibition: Attacking the Overshooting Inflammation @Fter Traumatic Brain Injury
Status: UNKNOWN
Conditions: Traumatic Brain Injury|Trauma, Head
Interventions: DRUG: C1 Inhibitor, Human|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Oral Carbohydrate and Fat Loads on Systemic Microvascular Endothelial Function in Healthy Individuals.
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: OTHER: sugar oral load|OTHER: fat oral load|OTHER: sugar and fat oral load
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Uridine on GABA and High Energy Phosphate Levels in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Male Subjects
Interventions: DRUG: Uridine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Rheumatoid Arthritis Study in Participants
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: LY2127399|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Imaging (MRI) for the Delineation of Organs At Risk (OAR) and Target Volumes in Lung Cancer Patients
Status: COMPLETED
Conditions: Lung Cancer
Interventions: OTHER: MRI scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Study of Risperidone Tablet 1 mg Under Fed Condition
Status: COMPLETED
Conditions: Fed
Interventions: DRUG: Risperidone Tablet 1 mg|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protamine Sulfate During Transcatheter Aortic Valve Implantation
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DRUG: Protamine sulfate|DRUG: 0.9% NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Cognitive Function as Measured by Repeated Cognitive Measures After 12 Weeks Treatment With Donepezil
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Donepezil|DRUG: Donepezil|DRUG: Placebo to match Aricept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tocilizumab for Painful Chronic Pancreatitis
Status: RECRUITING
Conditions: Pancreatitis, Chronic
Interventions: DRUG: Tocilizumab 20 MG/ML [Actemra]|DRUG: Sodium Chloride 0.9% Inj
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Effects of New Approach on Patients With Non-alcoholic Steatohepatitis
Status: RECRUITING
Conditions: Non-alcoholic Steatohepatitis
Interventions: DRUG: Rosuvastatin 20mg|DRUG: N-acetyl cysteine|DRUG: Rosuvastatin and N-acetyl cysteine|DRUG: Vita-E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single Oral Dose of 4 mg Cenerimod in Healthy Japanese and Caucasian Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Cenerimod|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of 5% Potassium Hydroxide With 10% Potassium Hydroxide Solution in Treatment of Molluscum Contagiosum
Status: COMPLETED
Conditions: Molluscum Contagiosum
Interventions: DRUG: potassium hydroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of AMG 706 in Subjects With Advanced Gastrointestinal Stromal Tumors (GISTs)
Status: COMPLETED
Conditions: Gastrointestinal Cancer
Interventions: DRUG: AMG 706
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization of Cerebral Tau Aggregates With 18F-RO6958948 PET in the ALFA Population
Status: ENROLLING_BY_INVITATION
Conditions: Healthy|Mild Cognitive Impairment
Interventions: PROCEDURE: Positron emission tomography with 18F-RO6958948
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of an Osteopathic Treatment for Mechanical Sucking Dysfunctions in Newborn
Status: COMPLETED
Conditions: Breastfeeding
Interventions: OTHER: osteopathic treatment|OTHER: usual breastfeeding counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Contrast-enhanced Ultrasonography Combined With Blue Dye as Dual-tracer for Sentinel Lymph Node Biopsy
Status: UNKNOWN
Conditions: Breast Neoplasms|Neoadjuvant Therapy|Sentinel Lymph Node Biopsy
Interventions: PROCEDURE: CEUS|PROCEDURE: blue dye
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Moringa Oleifera on Bone Density
Status: COMPLETED
Conditions: Osteoporosis, Osteopenia|Postmenopausal Osteoporosis
Interventions: DIETARY_SUPPLEMENT: Moringa Oleifera|DIETARY_SUPPLEMENT: Cabbage Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluate the Effect of Abdominal Electrical Muscle Stimulation on Abdominal Wall Restoration in Post - Partum Women
Status: COMPLETED
Conditions: Abdominal Wall Restoration|Diastasis Recti
Interventions: DEVICE: EMS device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Recombinant Human EPO on the Postoperative Neurologic Outcome in Pediatric Moyamoya Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Moyamoya Disease|Pediatrics|Cerebrovascular Disorders
Interventions: DRUG: erythropoietin|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of a Remote-Monitoring System to Diagnose and Treat Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea-hypopnea
Interventions: DEVICE: Telemedicine Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Commercial Blenderized Formula on Caloric Needs, Gastrointestinal Symptoms, and Gut Microbiome in Children With Cerebral Palsy (CP)
Status: NOT_YET_RECRUITING
Conditions: Cerebral Palsy
Interventions: DIETARY_SUPPLEMENT: commercial blenderized tube feed (CBTF)|DIETARY_SUPPLEMENT: commercial formulas (CF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Personalized Patient Derived Xenograft (pPDX) Modeling to Test Drug Response in Matching Host
Status: RECRUITING
Conditions: Colorectal Neoplasms|Colorectal Cancer|Breast Cancer|Breast Neoplasms|Ovarian Cancer|Ovarian Neoplasm
Interventions: OTHER: Molecular Profiling & In Vivo drug testing in pPDX and organoid cultures
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess the Efficacy and Safety of Beclomethasone Dipropionate in Adolescent and Adult Patients 12 Years of Age and Older With Persistent Asthma
Status: COMPLETED
Conditions: Persistent Asthma
Interventions: DRUG: Beclomethasone Dipropionate 640|DRUG: Placebo|DRUG: Beclomethasone dipropionate via 320 mcg BAI|DRUG: albuterol/salbutamol|DRUG: Beclomethasone dipropionate via 320 mcg MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Cannabidiol on Psychiatric Symptoms, Cognition, and Cannabis Consumption in Cannabis Users With Recent-Onset Psychosis
Status: WITHDRAWN
Conditions: Schizophrenia Spectrum Disorders|Cannabis Use
Interventions: DRUG: Cannabidiol (CBD)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomized Double-Blinded Placebo Controlled, Explorative Phase I Trial to Investigate the Safety and Tolerability of Two Different Doses of Topically Administered APOSEC™ in Healthy Male Subjects With Artificial Dermal Wounds
Status: COMPLETED
Conditions: Healthy|Artificial Dermal Wound
Interventions: DRUG: APOSEC™ for cutaneous use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Marketing-oriented Study to Evaluate the Comparative Bioavailability of Omega-3 Fatty Acids From Four Different Natural Health Products
Status: COMPLETED
Conditions: Comparative Bioavailability
Interventions: DIETARY_SUPPLEMENT: Omega-3 Fatty Acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Comparison Between a Pyrocarbon and a CoCr Shoulder Resurfacing Implant
Status: UNKNOWN
Conditions: Osteoarthritis of the Shoulder
Interventions: DEVICE: PyroTITAN, Ascension Orthopedics, Inc.|DEVICE: TITAN, Ascension Orthopedics, Inc.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring the Effectiveness of Sensor-based Balance Training on Patient Outcome Measures
Status: UNKNOWN
Conditions: Diabetes|Cancer|Multiple Sclerosis|Arthritis|Parkinson's Disease|Cognitive Disorders|Brain Injury|Stroke
Interventions: PROCEDURE: Exergame|PROCEDURE: Home based balance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes, Compliance and Effectiveness of Switching From Infliximab or Etanercept to Adalimumab in Patients With Active Rheumatoid Arthritis (RA). A Multicenter Post-Marketing Observational Study in Routine Clinical Use
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Retatrutide Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone (TRANSCEND-T2D-1)
Status: RECRUITING
Conditions: Diabetes Type 2
Interventions: DRUG: Retatrutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Skin-to-Skin Contact With a Sling in Primipar Mothers Who Delivered by Cesarean Section
Status: NOT_YET_RECRUITING
Conditions: Breast Feeding|Caesarean Section;Stillbirth
Interventions: OTHER: skin to skin with sling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevalence of Adenosine Deaminase (ADA) Enzyme Deficiency Disease in Adult Patients With Pulmonary Alveolar Proteinosis
Status: UNKNOWN
Conditions: Pulmonary Alveolar Proteinosis
Interventions: DIAGNOSTIC_TEST: adenosine deaminase test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Motor Cortex Stimulation for Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DEVICE: Motor cortex stimulation on.|DEVICE: motor cortex stimulation off
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Monitoring of Fluid Status in Heart Failure Patients by Intrathoracic Impedance Measurement (HomeCARE II)
Status: COMPLETED
Conditions: Heart Failure|Arrhythmias, Cardiac
Interventions: DEVICE: Intrathoracic impedance measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of the Combination of GX-188E Vaccination, GX-I7 and Pembrolizumab in Patients With Advanced, Resectable HPV Type 16 and/or 18 Positive Head and Neck Cancer
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: GX-188E, GX-I7, Pembrolizumab|DRUG: GX-188E, Pembrolizumab|DRUG: GX-188E, GX-I7, Pembrolizumab|DRUG: GX-188E, GX-I7
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib Study of Rad001 and Sutent to Treat Renal Cell Carcinoma
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Everolimus (RAD001)|DRUG: Sunitinib (Sutent)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-HIV Drugs for Treating Infants Who Acquired HIV Infection at Birth
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Abacavir sulfate|DRUG: Didanosine|DRUG: Efavirenz|DRUG: Lamivudine|DRUG: Lopinavir/Ritonavir|DRUG: Nevirapine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phenol Neurolysis of Genicular Nerves for Osteoarthritic Knee Pain
Status: UNKNOWN
Conditions: Osteoarthritis, Knee|Knee Pain Chronic
Interventions: DRUG: 6% aqueous phenol|DRUG: Isotonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-dependent Effects of Second-hand Smoke on Vascular Function
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: OTHER: Respirable suspended particles (RSP) PM 2.5 dose of second-hand smoke
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Canrenone as add-on Treatment in Moderate to Severe ARDS in COVID-19
Status: UNKNOWN
Conditions: COVID-19 Acute Respiratory Distress Syndrome
Interventions: DRUG: Potassium Canrenoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Opioid Use Among Justice-involved Youth as They Transition to Adulthood Leveraging Safe Adults (LeSA)
Status: RECRUITING
Conditions: Opioid Use|Substance Use
Interventions: BEHAVIORAL: Trust-based Relational Intervention Training|BEHAVIORAL: Trust-based Relational Intervention In-Home Structured Coaching|BEHAVIORAL: Trust-based Relational Intervention In-Home Responsive Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of Bulk-fill Composite Resins in Class II Restorations
Status: COMPLETED
Conditions: Dental Composite
Interventions: OTHER: Bulk-fill composite resin. (Dental Composite Resin Materials) (Dental filling materials)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Role of Brief Potent Glutamatergic Modulation in Addressing Problem Drinking
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: CI-581a|DRUG: CI-581b|BEHAVIORAL: MBRP|BEHAVIORAL: MET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Multimodal Prehabilitation to Improve Outcomes for Frail Patients Undergoing Resection of Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: BEHAVIORAL: Physical Exercise Program|DIETARY_SUPPLEMENT: Whey Protein Isolate Powder|BEHAVIORAL: Relaxation Techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Biodegradable Magnesium Bone Plate and Screw Fixation in Jaw Surgery
Status: NOT_YET_RECRUITING
Conditions: Orthognathic Surgical Procedures
Interventions: PROCEDURE: Magnesium bone plate and screw fixation in jaw surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coversin in PNH in Patients With Resistance to Eculizumab Due to Complement C5 Polymorphisms
Status: ENROLLING_BY_INVITATION
Conditions: Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions: DRUG: Coversin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Intrathecal Morphine With Modified Thoracoabdominal Nerve Block Through Perichondral Approach in Major Abdominal Surgery
Status: RECRUITING
Conditions: Opioid Use|Postoperative Pain
Interventions: PROCEDURE: Regional Block Comparison
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Efficacy and Safety of Using Prophylactic Abdominal Drainage After Cholecystectomy
Status: COMPLETED
Conditions: Drainage|Laparoscopic Cholecystectomy|Acute Cholecystitis
Interventions: DEVICE: Prophylactic Drain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 3D Printed Bolus in Post-mastectomy Radiotherapy
Status: UNKNOWN
Conditions: Breast Neoplasms|Radiotherapy Side Effect
Interventions: OTHER: customized 3D-printed bolus fabricated based on reconstruction of computed tomography (CT) images
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: iDecide.Decido: Diabetes Medication Decision Support Study
Status: COMPLETED
Conditions: Diabetes, Type 2
Interventions: BEHAVIORAL: Community Health Worker Diabetes Education: Print media|BEHAVIORAL: CHW Diabetes Education: tailored web site
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of ASP1941 in Healthy Male Taiwanese Subjects
Status: COMPLETED
Conditions: Healthy|Pharmacokinetics of ASP1941
Interventions: DRUG: ASP1941|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: CirculAting Tumor DNA in Patients DIagnosed With Lung Metastasis From Colorectal Cancer: candiDate Selection for Local AblaTive thErapy
Status: UNKNOWN
Conditions: Colorectal Cancer|Lung Metastases
Interventions: OTHER: Diagnostic Test: liquid biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Misoprostol for Cervical Priming Prior to Vacuum Aspiration
Status: COMPLETED
Conditions: First Trimester Pregnancy|Surgical Termination of Pregnancy
Interventions: DRUG: Misoprostol sublingual, 1h|DRUG: Placebo sublingual,1h|DRUG: Misoprostol sublingual, 3h|DRUG: Misoprostol vaginal, 1h|DRUG: Misoprostol vaginal, 3h|DRUG: Placebo sublingual, 3h|DRUG: Placebo vaginal, 1h|DRUG: Placebo vaginal, 3h
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Tart Cherry Juice Intervention on Vascular Function
Status: COMPLETED
Conditions: Dietary Exposure|Metabolic Disturbance
Interventions: DIETARY_SUPPLEMENT: Cherry juice|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Surgery Combined With Maintenance Targeted Therapy in the Treatment of Advanced Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma
Interventions: PROCEDURE: Primary debulking surgery|PROCEDURE: Neoadjuvant chemotherapy|DRUG: PARP inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-risk Recurrent or Second Primary HNSCC With PD-1 Antibody Adjuvant After Salvage Surgery(RePASS)
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dry Needling on Electromyographic Activity and Ultrasonographic Characteristics in Post-Stroke Spasticity
Status: RECRUITING
Conditions: Spasticity as Sequela of Stroke
Interventions: OTHER: Dry needling + usual care|OTHER: Sham dry needling + usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT