pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cytokine and Visual Outcome Variations in Eyes Receiving Aflibercept
Status: UNKNOWN
Conditions: Age Related Macular Degeneration|Diabetic Macular Edema|Retinal Vein Occlusion|Macular Edema
Interventions: DRUG: Intravitreal aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Electric Fans for Mitigating Thermal Strain in Older Adults During Heat Waves
Status: COMPLETED
Conditions: Hyperthermia|Weather; Heat|Heat Stress|Aging
Interventions: OTHER: No cooling (control)|OTHER: Electric fan (low airflow)|OTHER: Electric fan (high airflow)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Influence of Early and Continuous Exposure of Infants to Cow's Milk Formula on the Prevention of Milk Allergy
Status: UNKNOWN
Conditions: Cow Milk Allergy|Newborns
Interventions: DIETARY_SUPPLEMENT: cow's milk formula
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Periurethral vs Intravaginal Estrogen for Prevention of Recurrent Urinary Tract Infections
Status: RECRUITING
Conditions: Recurrent Urinary Tract Infection
Interventions: DRUG: Periurethral application of estradiol cream|DRUG: Intravaginal application of estradiol cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating Efficacy of Smart Device in Assisting With Inhaler Technique and Adherence
Status: UNKNOWN
Conditions: Asthma|Adherence, Medication|Childhood Asthma
Interventions: DEVICE: CapMedic smart inhaler device|BEHAVIORAL: Video-based guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Effect of Latanoprostene Bunod Ophthalmic Solution 0.024% on Episcleral Venous Pressure and Outflow Facility in Participants With Ocular Hypertension
Status: WITHDRAWN
Conditions: Ocular Hypertension
Interventions: DRUG: Latanoprostene Bunod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine and Propofol Combination Versus Propofol for Upper Gastrointestinal Endoscopy
Status: TERMINATED
Conditions: Obesity|Bariatrics|Sleep Apnea Syndromes|Gastric Bypass|Endoscopy
Interventions: DRUG: Ketofol|DRUG: Propofol|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Evaluate the Cardiac Safety of Pegylated Liposomal Doxorubicin Concurrently Plus Trastuzumab and Pertuzumab in the Adjuvant Setting for Early-stage HER-2-positive Breast Cancer: a Multicenter, Randomized Controlled Clinical Study
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Pegylated liposomal doxorubicin|DRUG: Epirubicin|DRUG: Cyclophosphamid|DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin or Carboplatin Combined With Gemcitabine in Locally Advanced, Recurrent, or Metastatic Malignant Salivary Gland Tumor
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: carboplatin|DRUG: cisplatin|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lung Recruitment and Postoperative CPAP
Status: COMPLETED
Conditions: Anesthesia
Interventions: DEVICE: Engström Datex-Ohmeda ICU Ventilator|DEVICE: Postoperative CPAP mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Duration of Analgesic Effect for Ultrasound Guided Supraclavicular Blocks With the Addition of Buprenorphine to Local Anesthetic Solution
Status: TERMINATED
Conditions: Regional Block for Pain Control|Supraclavicular Block|Ultrasound Guided Block|Block Additive
Interventions: DRUG: Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Study in Adult Surgical Patients of 5 Airway Devices
Status: COMPLETED
Conditions: Laryngoscopy|Intubation
Interventions: DEVICE: Macintosh laryngoscope|DEVICE: Airtraq® Optical Laryngoscope|DEVICE: Storz DCI Video Laryngoscope®|DEVICE: GlideScope® Video Laryngoscope|DEVICE: McGRATH® Video Laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oral Paricalcitol in Stage 3 - 5 Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: paricalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Toronto Association in the Treatment of Erectile Dysfunction and Premature Ejaculation
Status: NOT_YET_RECRUITING
Conditions: Erectile Dysfunction|Premature Ejaculation
Interventions: DRUG: Toronto association|DRUG: Tadalafil|OTHER: Tadalafil placebo|OTHER: Toronto association placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of ATX-101 on QT/QTc Intervals
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ATX-101 (10 mg/ml)|DRUG: ATX-101 (20 mg/ml)|DRUG: Moxifloxacin (400 mg)|DRUG: Placebo vehicle (PBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study Of BRL49653C For The Treatment Of Type 2 Diabetes (Combination Therapy With Sulfonyl Urea) -With Placebo Study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Rosiglitazone (BRL49653C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Investigate the Pharmacokinetics and Safety/Tolerability of CKD-386 in Healthy Male Volunteers
Status: UNKNOWN
Conditions: Hypertension|Dyslipidemias
Interventions: DRUG: CKD-386 formulation 1|DRUG: CKD-386 formulation 2|DRUG: D326, D337 and D013
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Fixed Pramlintide: Insulin Dose Ratio on Postprandial Glucose in Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Pramlintide acetate|DRUG: Placebo|DRUG: Lispro insulin U-100|DRUG: Regular insulin U-100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity and Intermittent Exercise Training for Cardiovascular and Cognitive Gain in Obese Women
Status: COMPLETED
Conditions: Obesity|Cognitive Ability, General|Cardiovascular Disease
Interventions: BEHAVIORAL: Interval exercise training|BEHAVIORAL: Continuous exercise training (CON)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Laparoscopic Ovarian Drilling on Outcomes of in Vitro Fertilisation in Clomiphene-resistant Women With Polycystic Ovary Syndrome
Status: UNKNOWN
Conditions: PCOS
Interventions: PROCEDURE: IVF/ICSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Bioequivalence Study Between Two Nicotine Replacement Therapies in Adult Healthy Smokers Motivated to Quit.
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: DRUG: Nicorette Strongmint lozenge 4 mg|DRUG: Niquitin MiniMint lozenge 4 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of a Curriculum Intervention on Asthma Knowledge in Adolescents of a Public School in Salvador-Bahia-Brazil
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: Knowledge about Asthma and Respiratory Education (KARE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cetuximab and/or Dasatinib in Patients With Colorectal Cancer and Liver Metastases That Can Be Removed by Surgery
Status: TERMINATED
Conditions: Liver Metastases|Mucinous Adenocarcinoma of the Colon|Mucinous Adenocarcinoma of the Rectum|Recurrent Colon Cancer|Recurrent Rectal Cancer|Signet Ring Adenocarcinoma of the Colon|Signet Ring Adenocarcinoma of the Rectum|Stage IV Colon Cancer|Stage IV Rectal Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: dasatinib|PROCEDURE: therapeutic conventional surgery|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Tahini in Oxidative Stress and Endothelial Function in Diabetes
Status: COMPLETED
Conditions: Oxidative Stress|Endothelial Function|Blood Pressure|Arterial Stiffness|Blood Glucose|Diabetes Mellitus, Type 2
Interventions: OTHER: tahini and bread|OTHER: margarine, cheese and bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Use of a Biodegradable Endoprothesis in the Prevention of Post-Endoscopic Retrograde CholoangioPancreatography Pancreatitis
Status: UNKNOWN
Conditions: Obstructive Jaundice|Biliary Stricture|Sphincter of Oddi Dysfunction
Interventions: DEVICE: Placement of ARCHIMEDES fast biodegradable stent during the Endoscopic Retrograde CholoangioPancreatography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Non Alcoholic Fatty Liver Disease Patients
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DRUG: Placebo|DRUG: Resmetirom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Intercoat (Oxiplex/AP Gel)in Decreasing Intrauterine Adhesions
Status: COMPLETED
Conditions: Asherman Syndrome
Interventions: DRUG: Oxiplex/AP gel|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Metabolism-informed Care for Smoking Cessation
Status: COMPLETED
Conditions: Tobacco Use|Tobacco Use Cessation
Interventions: OTHER: Nicotine Metabolite Ratio|DRUG: Varenicline|DRUG: Bupropion|DRUG: Nicotine patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Two Toric Contact Lenses on Current Toric Wearers
Status: COMPLETED
Conditions: Ametropia
Interventions: DEVICE: senofilcon A toric|DEVICE: alphafilcon A toric
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Reducing Stress-Sensitive Problems Among Pregnant Black Women With Childhood Adversity
Status: ACTIVE_NOT_RECRUITING
Conditions: Maternal Psychological Distress|Perinatal Depression|Self-Regulation, Emotion
Interventions: BEHAVIORAL: Trauma Informed Prenatal Intervention (TPI)|OTHER: Prenatal Education Topics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety of Administering a Second Dose of a COVID-19 mRNA Vaccine in Individuals Who Experienced a Systemic Allergic Reaction to an Initial Dose
Status: COMPLETED
Conditions: Systemic Allergic Reaction
Interventions: BIOLOGICAL: Pfizer-BioNTech COVID-19 Vaccine (Comirnaty)|OTHER: Placebo|BIOLOGICAL: Pfizer-BioNTech COVID-19 Vaccine, Bivalent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: SOI Immediately vs Delayed
Status: NOT_YET_RECRUITING
Conditions: Dental Implant|Dental Implant-Abutment Design
Interventions: DEVICE: Immediately implant placement|DEVICE: Delayed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Preoperative Local Water-Filtered Infrared-A (wIRA) Irradiation on Postoperative Wound Healing
Status: COMPLETED
Conditions: Wound Infection Rate After Surgery|Impact of Wound Infection on Pain and Wound Healing
Interventions: DEVICE: wIRA irradiation|OTHER: visible light only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Steroid-Eluting Stent Implant for the Treatment of Radiation-Related Sinusitis
Status: RECRUITING
Conditions: Radiation-Induced Mucositis
Interventions: PROCEDURE: Steroid-eluting stent implantation|DRUG: Steroid nasal spray|PROCEDURE: nasal saline rinses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Circulating Tumour Markers Early Variations and Clinical Response in First Line Treatment of Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Circulating Markers|Metastatic Colorectal Cancer
Interventions: PROCEDURE: Blood sampling for free mutant DNA analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Noninvasive Phrenic Nerve Neuromodulation in Shoulder Pain and Hepatobiliary Visceral Comorbidity.
Status: RECRUITING
Conditions: Shoulder Pain
Interventions: DEVICE: Phrenic nerve neuromodulation|PROCEDURE: common Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Esomeprazole in Treating Gastro-esophageal Reflux Disease (GERD) in Head and Neck Cancer Patients Exposed to Radiation Therapy
Status: TERMINATED
Conditions: Gastro-esophageal Reflux
Interventions: DRUG: Esomeprazole (Nexium)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: C Reactive Protein (CRP) Intervention to Reduce Inappropriate Antibiotic Prescriptions in the Primary Healthcare Setting
Status: COMPLETED
Conditions: Acute Respiratory Infections
Interventions: PROCEDURE: Patients will be tested by rapid POC CRP test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Capecitabine Maintenance Therapy Following Capecitabine Combined With Docetaxel in Treatment of mBC
Status: UNKNOWN
Conditions: Breast Neoplasms|Neoplasms by Site|Neoplasm Metastasis|Breast Diseases|Skin Diseases
Interventions: DRUG: Docetaxel plus Capecitabine|DRUG: Intermittent Capecitabine|DRUG: Metronomic Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Guselkumab on Cardiovascular Risk Surrogate Markers in Participants With Moderate to Severe Plaque Psoriasis
Status: TERMINATED
Conditions: Psoriasis
Interventions: DRUG: Guselkumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of the Intramuscular Route of the Anti-Flu Vaccine in Patients Receiving Oral Anticoagulation Therapy
Status: COMPLETED
Conditions: Influenza
Interventions: PROCEDURE: Influenza vaccine intramuscular administration route
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Application of the Medyria TrackCath System in Endovascular Repair of Abdominal Aortic Aneurysms (AAA)
Status: COMPLETED
Conditions: Aortic Aneurysm, Abdominal|Aortic Aneurysm, Thoracoabdominal|Acute Renal Failure|Acute Kidney Injury|Acute Kidney Failure|Acute Renal Insufficiency
Interventions: DEVICE: Medyria TrackCath System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Eccentric Muscle Training and Proprioceptive Neuromuscular Facilitation Techniques in Neck Pain
Status: COMPLETED
Conditions: Neck Pain|Chronic Pain
Interventions: OTHER: proprioceptive neuromuscular facilitation technique group|OTHER: eccentric muscle training technique application group|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bryostatin 1 and High Dose Cytarabine in Treating Patients With Refractory or Relapsed Leukemia or Lymphoma
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: DRUG: bryostatin 1|DRUG: cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D3 Supplementation on Muscle Mass in ICU Patient
Status: UNKNOWN
Conditions: Vitamin D Deficiency|Sarcopenia|Critical Illness
Interventions: DRUG: Vitamin D3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regular Antibacterial Photodynamic Therapy on Oral Hygiene in Elderly Residents
Status: COMPLETED
Conditions: Dental Plaque|Pus Collection|Oral Disease|Dryness Oral|Tooth Decay
Interventions: DEVICE: Lumoral Treatment|OTHER: Standard oral hygiene instructions according to the Finnish Dental Association
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Formoterol on the Counterregulatory Hormonal Response to Hypoglycemia in Type 1 Diabetes.
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Formoterol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells Under Basiliximab/Low Dose RATG to Induce Renal Transplant Tolerance
Status: TERMINATED
Conditions: Kidney Transplant
Interventions: BIOLOGICAL: Mesenchymal stem cells infusion, Basiliximab,Methylprednisolone,RATG ,Cyclosporine ,Mycophenolate mofetil|DRUG: Basiliximab, Methylprednisolone,RATG,Cyclosporine,Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intermittent Boluses Versus Infusion of Propofol During Gastroscopy
Status: NOT_YET_RECRUITING
Conditions: Anesthesia
Interventions: DRUG: Propofol 100 MG in 10 ML Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 2 Trial of Antisense Nucleotide to PKC-Alpha (LY900003, ISIS 3521) Plus Gemcitabine and Carboplatin in Patients With Advanced, Previously Untreated Non-Small Cell Lung Cancer.
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Pulmonary Neoplasms|Neoplasms, Lung
Interventions: DRUG: Gemcitabine|DRUG: Carboplatin|DRUG: LY900003
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diffuse Large B Cell Lymphoma of the Adult: Randomization Between High Dose Chemotherapy With Rituximab and CHOP 14-Rituximab
Status: COMPLETED
Conditions: Lymphoma, Large-Cell, Diffuse
Interventions: DRUG: CHOP+RITUXIMAB|DRUG: CEEP-RITUXIMAB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Intergenerational, Cognitively Enriched Intervention for MCI Patients and Their Children.
Status: ENROLLING_BY_INVITATION
Conditions: Mild Cognitive Impairment
Interventions: OTHER: No intervention, interviews with MCI patients as part of the development phase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multiple Ascending Dose Study of CM338 in Healthy Volunteers
Status: UNKNOWN
Conditions: Healthy Subjects
Interventions: BIOLOGICAL: CM338 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pegzilarginase and Pembrolizumab for Extensive Disease Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small-cell Lung Cancer
Interventions: DRUG: Pegzilarginase|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Two Types of Endometrial Activation Prior to Embryo Transfer
Status: COMPLETED
Conditions: Infertility|Endometrial Disorder
Interventions: PROCEDURE: Endometrial scratch with Pipelle curette|PROCEDURE: Endometrial scratch with Shepard catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of Chronic Rhinosinusitis on the Health-Related Quality of Life Among Adults With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: BEHAVIORAL: Cystic Fibrosis Questionnaire (Revised) for Teens/Adults
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Evaluation of the (Serodase 5 mg Tablet) in the Treatment of Inflammation After Third Molar Surgery
Status: UNKNOWN
Conditions: Trismus|Swelling|Inflammation
Interventions: DRUG: Serodase 5 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Ferumoxytol to Iron Sucrose for the Treatment of Iron Deficiency Anemia in Adult Subjects With Chronic Kidney Disease
Status: COMPLETED
Conditions: Iron Deficiency|Anemia|Kidney Disease
Interventions: DRUG: Ferumoxytol|DRUG: Iron Sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing an Effective Intervention to Address Post-Corona-Virus-Disease-2019 Balance Disorders, Weakness and Muscle Fatigue in Individuals Aged 65+
Status: RECRUITING
Conditions: COVID-19
Interventions: DEVICE: Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Specified Drug-use Survey on Abilify Prolonged Release Aqueous Suspension for IM Injection (Prevention of Relapse of Mood Episodes in BP)
Status: ACTIVE_NOT_RECRUITING
Conditions: Bipolar Disorder I
Interventions: DRUG: Abilify prolonged release aqueous suspension for IM injection (Aripiprazole)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Exercise Training on the Function of HDL-Cholesterol, Endothelial Function and Endothelial Progenitor Cells in Patients With Coronary Artery Disease (HERCET-Study)
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: BEHAVIORAL: physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Clinical Study of TQB2450 Combined With Anlotinib in Limited-Stage Small Cell Lung Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Small Cell Lung Cancer Limited Stage
Interventions: DRUG: TQB2450+Anlotinib|DRUG: TQB2450 placebo + Anlotinib placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metformin and Lifestyle Intervention in Women With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial of Alloreactive Cell Infusion Following Transplantation of Haplotype Cells in Patients With Myeloid Malignancies
Status: TERMINATED
Conditions: Leukemia, Myeloid, Acute|Leukemia, Lymphoid|Myelodysplastic Syndromes|Leukemia, Myelogenous, Chronic
Interventions: DEVICE: CliniMACS CD34 Reagent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Block Versus Transversus Abdominis Plane Block In Laparoscopic Bariatric Surgery
Status: COMPLETED
Conditions: Erector Spinae Block|Bariatric Surgery Candidate
Interventions: PROCEDURE: transversus abdominis block|PROCEDURE: Erector spinae block|DRUG: Bupivacaine 0.25% Injectable Solution|DEVICE: Siemens Acuson x300 3-5MHz Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Investigating the Association of NP137 With Atezolizumab-Bevacizumab Combination in First Line in Unresectable HCC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: NP137|DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Effects of Exercise Breaks and Rest Breaks on Fatigue and Musculoskeletal Discomfort in Static Workstation Office Workers
Status: UNKNOWN
Conditions: Musculoskeletal Pain
Interventions: OTHER: Supplemental Micro Breaks|PROCEDURE: Exercise Breaks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Comparison of Anterior Knee Pain in Patella With or Without Denervation in Medial Unicompartmental Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: patella denervation|PROCEDURE: patella non-denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-Literacy Physician-Patient Intervention Promoting Colorectal Cancer Screening
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Physician Intervention|BEHAVIORAL: Physician and Patient Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bronchoprotective Effect of Arformoterol in Children With Exercise-Induced Bronchospasm (EIB)
Status: WITHDRAWN
Conditions: Exercise-induced Bronchospasm
Interventions: DRUG: arformoterol|DRUG: formoterol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Supportive Care for Cognitively Impaired Patients and Families
Status: ACTIVE_NOT_RECRUITING
Conditions: Dementia|Primary Palliative Care|Mild Cognitive Impairment
Interventions: BEHAVIORAL: nurse-led supportive care assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness and Safety of Tofacitinib in Patients With Extensive and Recalcitrant Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: Tofacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP1617 in Healthy Adult Non-Asian and Japanese Subjects Including Assessment of a Food Effect
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ASP1617|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Maintenance Durvalumab (MEDI4736) and Olaparib (AZD2281) After Standard 1st Line Treatment (Carboplatin/Cisplatin, Etoposide, Durvalumab) in HRD Positive Extensive Disease (ED) Small-cell Lung Cancer (SCLC)
Status: NOT_YET_RECRUITING
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: Durvalumab|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Home Gluten Immunogenic Peptide Testing on Children With Celiac Disease
Status: SUSPENDED
Conditions: Celiac Disease|Gluten Sensitivity|Gluten Enteropathy|Gastrointestinal Disease|Digestive System Disease|Diet Modification|Intestinal Disease|Malabsorption Syndromes|Patient Compliance|Diagnostic Self Evaluation|Quality of Life
Interventions: DEVICE: Immunochromatographic lateral flow test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigation of Dental Health in Children With Neutrophil Defects: A Clinical Study
Status: COMPLETED
Conditions: Primary Immune Deficiency Disorder|Periodontitis
Interventions: PROCEDURE: Oral hygiene advice, non surgical periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Gut Microbiota Modulation Effects of Allicin for Cardiovascular Disease Protection and Establishing Microbiota Directed Personalized Nutrition Guidance With Novel Humanized Gnotobiotic Mice Model, Microbial Culturomics and Metabolomic Technique
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DIETARY_SUPPLEMENT: Raw garlic juice containing allicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anorectal Manometery in Pediatric Chronic Refractory Constipation
Status: NOT_YET_RECRUITING
Conditions: Chronic Constipation
Interventions: DRUG: lubiprostone , single arm|PROCEDURE: biofeed back sessions|PROCEDURE: botox injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PERVIDEO I Registry, The Lutonix Paclitaxel-Coated Balloon Catheter for the Treatment of Coronary In-Stent Restenosis
Status: COMPLETED
Conditions: In-Stent Restenosis
Interventions: DEVICE: Lutonix Paclitaxel-Coated Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Academic Stress and Proinflammatory Cytokines: Omega-3 Intervention
Status: COMPLETED
Conditions: Stress-related Changes in Inflammation
Interventions: DIETARY_SUPPLEMENT: omega-3 supplementation|DIETARY_SUPPLEMENT: Oral omega-3 fish oil placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Stretching Device Versus Night Splints
Status: UNKNOWN
Conditions: Plantar Fasciitis
Interventions: DEVICE: Night splints|DEVICE: Triceps Surae Stretching and Flexibility Assessment Device (TESS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Investigating the Safety, Tolerability, and Pharmacokinetic Properties of Lu AE58054 in Healthy Japanese and Caucasian Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cohort A1: Lu AE58054 or placebo|DRUG: Cohort A2: Lu AE58054 or placebo|DRUG: Cohort B1: Lu AE58054
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SPIRIT III Clinical Trial of the XIENCE V® Everolimus Eluting Coronary Stent System (EECSS)
Status: COMPLETED
Conditions: Stents|Coronary Artery Disease|Total Coronary Occlusion|Coronary Artery Restenosis|Stent Thrombosis|Vascular Disease|Myocardial Ischemia|Coronary Artery Stenosis
Interventions: DEVICE: XIENCE V® Everolimus Eluting Coronary Stent|DEVICE: TAXUS® EXPRESS2™ Paclitaxel Eluting Coronary Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Survivorship Care Plans and Telehealth Education for the Improvement of Access to Cancer Survivorship, the IMPACT Study
Status: ENROLLING_BY_INVITATION
Conditions: Breast Carcinoma|Colorectal Carcinoma|Lung Carcinoma|Lymphoma|Prostate Carcinoma
Interventions: OTHER: Survivorship Care Plan|OTHER: Educational Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of SHR-1210 Plus Apatinib in Patients With Soft Tissue Sarcoma
Status: TERMINATED
Conditions: Sarcoma
Interventions: DRUG: SHR-1210 plus Apatinib|DRUG: ADM plus IFO or IFO alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of MRI Measures of Lung Water With Posture Changes in Healthy Volunteers and in Patients With Cardiac Failure
Status: COMPLETED
Conditions: Heart Failure, Congestive
Interventions: PROCEDURE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety & Efficacy of Corneal Collagen Cross-Linking in Eyes With Keratoconus or Corneal Ectasia After Refractive Surgery
Status: TERMINATED
Conditions: Keratoconus|Corneal Ectasia
Interventions: DEVICE: KXL System (15 mW/cm2)|DEVICE: KXL System (30 mW/cm2)|DEVICE: KXL System (45 mW/cm2)|DRUG: riboflavin ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Efgartigimod in Adult Patients With Primary Immune Thrombocytopenia (ITP).
Status: COMPLETED
Conditions: Primary Immune Thrombocytopenia
Interventions: BIOLOGICAL: efgartigimod|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation in Chronic Ankle Instability
Status: COMPLETED
Conditions: Ankle Sprains
Interventions: OTHER: ultrasound-guided percutaneous neuromodulation|OTHER: dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Immune Response Against Human Papillomavirus (HPV)in Patients With Metastatic Cancer of the Anal Canal
Status: COMPLETED
Conditions: Metastatic Anal Canal Cancer|Human Papillomavirus
Interventions: DRUG: DCF regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neoadjuvant Chemoradiation Therapy Combined With Immunotherapy for MSS Ultra-low Rectal Cancer
Status: RECRUITING
Conditions: Neoadjuvant Chemoradiation Therapy|Rectal Cancer|Immunotherapy|Microsatellite Instability Low
Interventions: DRUG: xintilimab injection|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dental Photography and Numeric Shade Quantification as a Substitute to Conventional and Instrumental Shade Matching Techniques in the Esthetic Zone
Status: RECRUITING
Conditions: Discoloration, Tooth|Chip Tooth|Non Vital Teeth|Trauma Dental
Interventions: DEVICE: Digital photography combined with eLABor_aid shade analyzing software|DEVICE: Spectrophotometer|DEVICE: Conventional visual shade matching
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Endodontic Study of Apical Preparation Size
Status: COMPLETED
Conditions: Chronic Apical Periodontitis of Pulpal Origin
Interventions: PROCEDURE: Endodontic procedure with varied apical preparation size
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: BCL6-rearrangements Implications in Non-Hodgkin Lymphomas.
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Hodgkin Lymphoma|Follicular Lymphoma|Marginal Zone Lymphoma|Diffuse Large B Cell Lymphoma
Interventions: OTHER: Histopathological analysis|GENETIC: Molecular analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of WhatsApp (a Messenger Program) Usage in Emergency Department (ED)
Status: COMPLETED
Conditions: Communication
Interventions: OTHER: whatsApp|OTHER: without whatsApp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pharmacological Study of High Doses of Ceftriaxone in Meningitidis
Status: COMPLETED
Conditions: Meningitis|Neurological Infections
Interventions: DRUG: Ceftriaxone treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study in Pediatric Volunteers of a Handheld Device Versus a Standard Diagnostic Device in Ophthalmic Refraction
Status: RECRUITING
Conditions: Refractive Errors|Accomodation|Diagnostic Self Evaluation
Interventions: DEVICE: EQ103
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bioequivalence Study of Ziprasidone HCL Capsules, 20 mg of Dr. Reddy's Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ziprasidone Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ADVANCE: An Observational Study To Determine Bortezomib Safety and Effectiveness at First Relapse After Participation In First Line HOVON-49/50 Clinical Studies.
Status: COMPLETED
Conditions: Multiple Myeloma|Hematological Neoplasms
Interventions: DRUG: Bortezomib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Physical Activiy Promotion Intervention Programs in Emerging Adulthood
Status: COMPLETED
Conditions: Body Composition|Health Behavior
Interventions: BEHAVIORAL: Treatment group|BEHAVIORAL: Contral group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: P-BCMA-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: P-BCMA-ALLO1 CAR-T cells|DRUG: Rimiducid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Erector Spinae Plane Block on Bariatric Surgery.
Status: COMPLETED
Conditions: Laparoscopic Bariatric Surgery
Interventions: PROCEDURE: Perioperative and postoperative multimodal analgesia|PROCEDURE: ESP Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Mobile Intervention Application (App) to Address Sexual Dysfunction in Hematopoietic Stem Cell Transplant Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Other Cancer
Interventions: BEHAVIORAL: Mobile App + enhanced standard care|OTHER: Enhanced Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial of GW572016, Gemcitabine and Oxaliplatin for Metastatic Pancreaticobiliary Cancer Schema
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: cohort 1|DRUG: cohort 2|DRUG: cohort 3|DRUG: cohort 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Rectus Sheath Block and Transversus Abdominis Plane Block
Status: COMPLETED
Conditions: Cholecystitis|Appendicitis
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of Compound From Brinjal Peel Extract in the Treatment of Palmar Arsenical Keratosis and Bowen's Disease
Status: UNKNOWN
Conditions: Keratotic Nodular Size
Interventions: DRUG: Brinjal peel extract containing cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Point-of-care Ultrasound in Suspected Pulmonary Embolism
Status: COMPLETED
Conditions: Pulmonary Embolism|Pulmonary Embolus/Emboli
Interventions: DIAGNOSTIC_TEST: Point-of-care-ultrasound examination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy of Denosumab in Decreasing Periprosthetic Bone Loss in Patients With Total Knee Arthroplasty
Status: COMPLETED
Conditions: Bone Resorption
Interventions: DRUG: Denosumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Using D-cycloserine to Enhance the Benefits of Cognitive Behavioral Therapy for Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: D-cycloserine|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Urinary Microbiome Changes Following Administration of 500 mg of NDS-446 in Women With Dry OAB at 12 Weeks
Status: RECRUITING
Conditions: Overactive Bladder
Interventions: DRUG: 500 mg NDS-446
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trifocal Diffractive Intraocular Lens After Cataract Extraction With Phacoemulsification
Status: COMPLETED
Conditions: Refractive Errors
Interventions: DEVICE: Trifocal diffractive intraocular lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Monotherapy vs Combination Therapy of Corticosteroids With GCSF in Severe Alcoholic Hepatitis Patients.
Status: UNKNOWN
Conditions: Alcoholic Hepatitis
Interventions: DRUG: Gcsf|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PREPARE - Primary Prevention Parameters Evaluation
Status: COMPLETED
Conditions: Tachycardia, Ventricular|Implantable Cardioverter Defibrillator (ICD)|Fibrillation, Ventricular|Syncope
Interventions: DEVICE: Implanted Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Biomarker-guided rTMS for Treatment Resistant Depression
Status: RECRUITING
Conditions: Treatment Resistant Depression|Major Depressive Disorder
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation|DEVICE: Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Ezetimibe/Simvastatin 10/20 mg Versus Simvastatin 40 mg in High Cholesterol and Coronary Heart Disease Study (P04039AM2)(COMPLETED)
Status: COMPLETED
Conditions: Hypercholesterolemia|Coronary Disease
Interventions: DRUG: Ezetimibe/Simvastatin 10/20 mg|DRUG: simvastatin 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nous-PEV: a Novel Immunotherapy for Lung Cancer and Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma (Skin)|Non-Small-Cell Lung Carcinoma
Interventions: BIOLOGICAL: GAd-PEV|BIOLOGICAL: MVA-PEV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT