pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Comparison of Tracheal Intubation Using the Totaltrack vs the Macintosh Laryngoscope in Obese Patients
Status: UNKNOWN
Conditions: Endotracheal Intubation|Obesity|Desaturation|Ventilation
Interventions: DEVICE: orotracheal intubation Macintosh Laryngoscope|DEVICE: orotracheal intubation Totaltrack VLM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: MelaViD: A Trial on Vitamin D Supplementation for Resected Stage II Melanoma Patients
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: Vitamin D3 ( Colecalciferol)|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Three Types of Nucleotide/Nucleoside Analogues Therapy in Patients With Chronic Hepatitis b
Status: RECRUITING
Conditions: Chronic Hepatitis b
Interventions: DRUG: Entecavir|DRUG: Tenofovir Disoproxil Fumarate|DRUG: Tenofovir Alafenamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diastolic Ventricular Interaction and the Effects of Biventricular Pacing in Hypertrophic Cardiomyopathy
Status: UNKNOWN
Conditions: Hypertrophic Cardiomyopathy
Interventions: DEVICE: Cardiac Resynchronisation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Two Doses of Dexmedetomidine as Adjuncts to Lidocaine for Intravenous Regional Anesthesia
Status: COMPLETED
Conditions: Limb Deformity
Interventions: DRUG: Lidocaine Hydrochloride 2%|DRUG: Dexmedetomidine 0.5 ug/kg|DRUG: Dexmedetomidine Injection 0.25 ug/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effects of Tibolone (Livial®) on Breast Tissue in Postmenopausal Women With Breast Cancer (Study 32971)(P06469)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: tibolone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The COMBINE Study: The CKD Optimal Management With BInders and NicotinamidE
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Nicotinamide|DRUG: Lanthanum Carbonate|DRUG: Placebo (for Nicotinamide)|DRUG: Placebo (for lanthanum carbonate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Comparing the Efficacy of Hybrid, High-dose Dual and Bismuth Quadruple Therapies
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: 10d bismuth quadruple therapy|DRUG: 14d hybrid therapy|DRUG: 14D high-dose dual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Peginterferon Lambda-1a vs. Peginterferon Alfa-2a, Plus Ribavirin in Subjects With Genotype 1 Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C Virus (HCV)
Interventions: BIOLOGICAL: Peginterferon Lambda-1a|DRUG: Ribavirin|BIOLOGICAL: Peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Combination of Hyaluronic Acid, Chondroitin Sulphate and Magnesium Trisilicate on Subjects With GastroEsophageal Reflux Disease
Status: COMPLETED
Conditions: Gastro Esophageal Reflux
Interventions: DEVICE: hyaluronic acid with chondroitin + sulphate + magnesium trisilicate|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Home Enteral Nutrition in Malnourished Patients With Gastrointestinal Cancer
Status: COMPLETED
Conditions: Malnutrition|Gastrointestinal Cancer
Interventions: DIETARY_SUPPLEMENT: Enteral nutrition|OTHER: Dietary counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dry Needling and Spinal Manipulation vs. Interocclusal Appliance (Splint), NSAIDs and Joint Mobs for Temporomandibular Dysfunction
Status: COMPLETED
Conditions: Temporomandibular Joint Dysfunction Syndrome
Interventions: OTHER: Dry Needling|OTHER: Spinal manipulation|OTHER: Interocclusal Appliance|DRUG: NSAIDs|OTHER: TMJ Mobs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-dose Furmonertinib in the Treatment in Patients With Advanced, Metastatic NSCLC With Progressed After First- or Second-line Treatment With Osimertinib
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Furmonertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of SLV213 for the Treatment of COVID-19.
Status: TERMINATED
Conditions: COVID-19
Interventions: OTHER: Placebo for SLV213|DRUG: SLV213
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Daily Activity and Gait Analysis After Viscosupplement Injection Among Hip Osteoarthritis Patients
Status: COMPLETED
Conditions: Hip Osteoarthritis
Interventions: DRUG: Hyaluronan|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect Of Power Breath Device On Arterial Blood Gases And Diaphragmatic Excursion After Valve Surgery
Status: COMPLETED
Conditions: Heart Valve Diseases
Interventions: OTHER: Power breath plus|OTHER: Incrementing the training load|OTHER: Diaphragmatic breathing exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Human Papillomavirus (HPV) Vaccination to Prevent Infection Among Women Living With HIV.
Status: NOT_YET_RECRUITING
Conditions: Human Papilloma Virus|Hiv
Interventions: BIOLOGICAL: GARDASIL®9|BIOLOGICAL: Menveo®/Menactra®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of ddI in Patients With AIDS Who Become Sicker While Taking Zidovudine
Status: COMPLETED
Conditions: HIV Infections|Leukoencephalopathy, Progressive Multifocal
Interventions: DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation in Workplaces in Hong Kong [Phase II]
Status: UNKNOWN
Conditions: Smoking
Interventions: BEHAVIORAL: workshop (Motivational intervention)|BEHAVIORAL: Health talk|BEHAVIORAL: Face to Face counseling|BEHAVIORAL: Phone counseling|BEHAVIORAL: SMS|BEHAVIORAL: Booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PK/PD and Safety/Tolerability of Two Dosing Regimens of Oral Fosfomycin Tromethamine in Healthy Adults
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Fosfomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Urothelial Cancer Tumor Bio-markers and Physical-spectroscopic Characteristic
Status: UNKNOWN
Conditions: Urothelial Carcinoma|Bladder Cancer|Urothelial Neoplasm|Urothelial Carcinoma Bladder|Urothelial Carcinoma in Situ
Interventions: OTHER: Biomarkers and proteomics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cisternostomy Vs Decompressive Craniectomy for Severe Traumatic Brain Injury
Status: NOT_YET_RECRUITING
Conditions: Severe Traumatic Brain Injury
Interventions: PROCEDURE: Decompressive Craniectomy|PROCEDURE: Cisternostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of AJU-A51 in Type 2 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: DRUG: AJU-A51|DRUG: A51R2|DRUG: A51R3|DRUG: AJU-A51 Placebo|DRUG: A51R2 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Orcellex® Brush Versus Cervex-Brush® on Vault Smear Adequacy in Patients Treated With Radiotherapy for Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: DEVICE: Orcellex Brush|DEVICE: Cervex Brush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Cyclosporine and Prognosis in Acute Myocardial Infarction (MI) Patients
Status: COMPLETED
Conditions: ST Elevation Acute Myocardial Infarction
Interventions: DRUG: Injection of Cyclosporin|DRUG: Placebo|PROCEDURE: Echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Safety And Efficacy Of IPX066 In Advanced Parkinson's Disease (ADVANCE-PD).
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: IPX066|DRUG: IR CD-LD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanical Determinants of Upper Limbs Oscillation During Gait
Status: RECRUITING
Conditions: Multiple Sclerosis|Poststroke/CVA Hemiparesis|Parkinson Disease|Cerebral Palsy|Amputation
Interventions: OTHER: Healthy subjects|OTHER: Pathologic group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: "Light" Versus "Deep" Bispectral Index (BIS) Guided Sedation for Colonoscopy
Status: COMPLETED
Conditions: Anaesthesia
Interventions: OTHER: Sedation depth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Thymosin Beta 4 in Patients With Pressure Ulcers
Status: COMPLETED
Conditions: Pressure Ulcers
Interventions: DRUG: Placebo|DRUG: Thymosin Beta 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oscillating Positive Expiratory Pressure (OPEP) Therapy in High Risk Patients Following Cardiac Surgery
Status: UNKNOWN
Conditions: Cardiac Surgery|Coronary Artery Bypass Grafting|Chronic Obstructive Pulmonary Disease (COPD)|Older Adults|Postoperative Pulmonary Complications
Interventions: DEVICE: Oscilatory Positive Expiratory Pressure (OPEP) device|DEVICE: SHAM Device Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicentric Study an Endoscopic Treatment of Digestive Neoplasia by Submucosal Dissection Evaluation of a New Water Jet System
Status: COMPLETED
Conditions: Stomach Neoplasm|Intestinal Neoplasm|Rectal Neoplasm
Interventions: PROCEDURE: endoscopic sub-mucosal dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study to Assess Long-term Safety, Tolerability, and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-4)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Xanomeline and Trospium Chloride Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: It´s Up To You: Update and Digitalization of a Universal School-based Prevention Intervention for Drug Initiation and Use
Status: ACTIVE_NOT_RECRUITING
Conditions: Substance Use|Behavior, Addictive|Smoking Behaviors|Alcohol Drinking|Illicit Drug Use
Interventions: BEHAVIORAL: "It´s Up To You" program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adjuvant Stereotactic Body Radiotherapy (SBRT) for Hepatocellular Carcinoma After Hepatectomy With Narrow Margin: a Prospective, Multi-center, Randomized Controlled, Open-labelled, Phase III Study
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma|Narrow Margin|Adjuvant Stereotactic Body Radiotherapy|Hepatectomy
Interventions: RADIATION: stereotactic body radiation therapy|OTHER: regular follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Efficacy of Attentional-Control Training in Sickle Cell Disease
Status: RECRUITING
Conditions: Sickle Cell Disease|Attention Deficit|Cognitive Deficit in Attention
Interventions: DEVICE: EndeavorRx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Motivated, Action-based Intervention on Health Outcomes of Coronary Heart Disease Patients
Status: SUSPENDED
Conditions: Coronary Heart Disease
Interventions: BEHAVIORAL: 1. Education|BEHAVIORAL: 2. Exercise|BEHAVIORAL: 3. Telephone follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tackling Disruptions to Frailty Interventions: Developing Personalized Interventions Targeted for Older Persons With Cardiac Frailty
Status: RECRUITING
Conditions: Cardiovascular Diseases
Interventions: OTHER: Intervention Set A|OTHER: Intervention Set B|OTHER: Intervention Set C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanical Ventilation During Cardiopulmonary Bypass
Status: UNKNOWN
Conditions: Congenital Heart Disease|Mechanical Ventilation Complication|Cardiopulmonary Bypass
Interventions: PROCEDURE: Ventilation during cardiopulmonary bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Epidural Blood Patch on the Resolution of Postdural Puncture Headache (PDPH)
Status: WITHDRAWN
Conditions: Post-Lumbar Puncture Headache
Interventions: OTHER: Epidural Blood Patch|OTHER: Epidural Blood Patch|OTHER: Epidural Blood Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 17AAG to Treat Kidney Tumors in Von Hippel-Lindau Disease
Status: COMPLETED
Conditions: Hippel-Lindau Disease|Kidney Cancer
Interventions: DRUG: 17 allylamino-17-demethoxygeldanamycin|DRUG: 18 FDG (Fludeoxyglucose 18F)|DRUG: [15-O] H2O|DRUG: EPL diluent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Comparing Efficacy And Safety Of Sunitinib Versus Placebo For TheTreatment Of Patients At High Risk Of Recurrent Renal Cell Cancer
Status: COMPLETED
Conditions: Kidney Neoplasms
Interventions: DRUG: Sunitinib malate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Functional Performance Study of The Wondaleaf Female Condom
Status: COMPLETED
Conditions: HIV Prevention|Pregnancy Prevention
Interventions: DEVICE: Wondaleaf Female Condom|DEVICE: FC2 Female Condom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Telcagepant for Prevention of Menstrually Related Migraine in Female Participants With Episodic Migraine (MK-0974-065)
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Telcagepant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Good Night Project: Behavioural Sleep Interventions for Children With ADHD: A Randomised Controlled Trial
Status: UNKNOWN
Conditions: Attention Deficit Hyperactivity Disorders|Neurodevelopmental Disorders|Attention Deficit Disorder With Hyperactivity
Interventions: BEHAVIORAL: Good Night Project
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SECOX as Neoadjuvant Therapy in Patients With Locally Advanced HCC
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sorafenib|DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Inhibition of CYP3A4/5 by Itraconazole on the PK of CHF6001 (Tanimilast)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: CHF6001 DPI|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Hydroxychloroquine and Azithromycin for the Treatment of Ambulatory Patients With Mild COVID-19
Status: SUSPENDED
Conditions: Covid-19
Interventions: DRUG: Hydroxychloroquine Sulfate|DRUG: Azithromycin Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ibrutinib Combined With Venetoclax in Subjects With Mantle Cell Lymphoma (SYMPATICO)
Status: COMPLETED
Conditions: Mantle-Cell Lymphoma
Interventions: DRUG: Ibrutinib|DRUG: Venetoclax|DRUG: Placebo Oral tablet to match Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Ginkgo Biloba Extract in the Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: COMBINATION_PRODUCT: Ginkgo biloba extract + standard treatment( paracetamol+Diclofenac100mg SR)|COMBINATION_PRODUCT: placebo in addition to the standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of Prevention of Postoperative Delirum to Reduce Incidence of Postoperative Cognitive Dysfunction
Status: COMPLETED
Conditions: Postoperative Cognitive Dysfunction|Postoperative Delirium
Interventions: OTHER: monitoring and non-medical prophylaxis of delirium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Prescription Medications in Marijuana Users
Status: COMPLETED
Conditions: Marijuana Abuse
Interventions: DRUG: Dronabinol 30mg/day|DRUG: Dronabinol 60mg/day|DRUG: Dronabinol 120mg/day|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Restoring Hand Function Utilizing Nerve Transfers in Persons With Cervical Spinal Cord Injuries
Status: TERMINATED
Conditions: Cervical Spinal Cord Injury|Spinal Cord Injuries|Traumatic Spinal Cord Compression
Interventions: PROCEDURE: Upper extremity nerve transfer surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Random Controlled Test (RCT): Acupuncture Treatment on Nonspecific Low Back Pain (NLBP)
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: OTHER: Acupuncture Treatment|OTHER: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dietary Lipids as Primary Modulators of Carotenoid Absorption in Vegetables
Status: COMPLETED
Conditions: Absorption of Carotenoids From Vegetables
Interventions: OTHER: Soybean Oil|OTHER: Canola Oil|OTHER: Butter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Anaferon for Children in the Treatment of Influenza and Acute Respiratory Viral Infections in Children
Status: COMPLETED
Conditions: Influenza and Acute Respiratory Viral Infections
Interventions: DRUG: Anaferon for Children
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stress & Resilience Study
Status: ENROLLING_BY_INVITATION
Conditions: Stress|Stress, Psychological|Stress, Physiological|Stress, Emotional|Stress Reaction
Interventions: BEHAVIORAL: Education Program|BEHAVIORAL: Think Well Program|BEHAVIORAL: Be Well Program|BEHAVIORAL: Eat Well Program|BEHAVIORAL: Sleep Well Program|BEHAVIORAL: Move Well Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gene-Environment-Interaction: Influence of the COMT Genotype on the Effects of Different Cannabinoids - a PET Study
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers|Modeling Psychosis
Interventions: DRUG: Delta-9-tetrahydrocannabinol|DRUG: Cannabidiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Femtosecond Laser-assisted Corneal Debridement for Herpes Simplex Keratitis
Status: UNKNOWN
Conditions: Herpes Simplex Keratitis
Interventions: PROCEDURE: FLDEB|DRUG: Ganciclovir (GCV)|DEVICE: Femtosecond laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative, Controlled Study to Evaluate the Lay User Accuracy and Performance of the Dip Home-Based Dipstick Analyzer
Status: COMPLETED
Conditions: Urine Detectable Acute and Chronic Diseases
Interventions: DIAGNOSTIC_TEST: Dip Home-Based Dipstick Analyzer|DEVICE: Urine analysis predicate device for professional user
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Role of Radiotherapy Following Oesophageal Stenting in Cancer
Status: COMPLETED
Conditions: Oesophageal Cancer
Interventions: PROCEDURE: oesophageal stenting with self expandable metal stent|PROCEDURE: Oesophageal stent followed by external beam radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Filling Bone Erosions: a Longitudinal Multicentric HR-pQCT Study of Subcutaneous Tocilizumab in Rheumatoid Arthritis
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: subcutaneous tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stroke School -Including Physical Exercise, Patient Education and Individual Follow-up Sessions
Status: RECRUITING
Conditions: Minor Stroke|Non-disabling Stroke|Transient Ischemic Attack
Interventions: BEHAVIORAL: Cardiorespiratory exercise combined with patient education and individual follow-up sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Optimising Preconceptual Health in Subfertile PCOS Patients Using a Lifestyle Modification Program
Status: TERMINATED
Conditions: Infertility, Female|Polycystic Ovarian Syndrome|Lifestyle
Interventions: BEHAVIORAL: Lifestyle program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Heart Failure Risk in Late-Life With Physical Activity
Status: NOT_YET_RECRUITING
Conditions: Hypertension|Exercise Training|Cardiac Rehabilitation|Proteomics
Interventions: BEHAVIORAL: Cardiac Rehabilitation|BEHAVIORAL: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: D-cycloserine Augmentation of Cognitive Behavioral Therapy (CBT) for Pediatric Obsessive-compulsive Disorder (OCD)
Status: COMPLETED
Conditions: Obsessive-compulsive Disorder
Interventions: BEHAVIORAL: Cognitive-behavioral therapy|DRUG: d-cycloserine|DRUG: Pill placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ocrelizumab on Neuroinflammation in Multiple Sclerosis as Measured by 11C-PBR28 MR-PET Imaging of Microglia Activation
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: DRUG: 11C-PBR28
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treatment Targets for Chronic Hypertension in Pregnancy
Status: WITHDRAWN
Conditions: Pregnancy Toxemia|Hypertension|Proteinuria
Interventions: DRUG: methyldopa|DRUG: labetalol|DRUG: nifedipine|DRUG: clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thoracic Epidural Analgesia vs Surgical Site Infiltration With Liposomal Bupivacaine Following Open Gynecologic Surgery
Status: RECRUITING
Conditions: Surgery|Analgesia
Interventions: DRUG: Liposomal bupivacaine|OTHER: Thoracic epidural analgesia (bupivacaine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of an Anti-cancer Viral Gene Therapy, Toca 511/Toca FC, to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed Glioblastoma
Status: WITHDRAWN
Conditions: Anaplastic Astrocytoma|Glioblastoma|Oligodendroglioma|Supratentorial Glioblastoma
Interventions: DRUG: Extended Release Flucytosine|DEVICE: NovoTTF-100A Device|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Radiation Therapy|DRUG: Temozolomide|PROCEDURE: Therapeutic Conventional Surgery|BIOLOGICAL: Vocimagene Amiretrorepvec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine Treatment Effects of Denosumab in Patients With Breast Cancer Receiving Aromatase Inhibitor Therapy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Placebo|BIOLOGICAL: Denosumab|DRUG: Non-steroidal aromatase inhibitor therapy|DRUG: Zoledronic Acid|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Vitamin D Supplementation on Improvement of Pneumonic Children
Status: UNKNOWN
Conditions: Child, Hospitalized|Vitamin D Deficiency|Pneumonia
Interventions: DRUG: A single one ml injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stool Testing With Molecular Assay to Minimize Contact Precautions
Status: COMPLETED
Conditions: Infectious Gastroenteritis
Interventions: DIAGNOSTIC_TEST: Conventional Stool Testing|DIAGNOSTIC_TEST: BioFire FilmArray Gastrointestinal Panel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: RESTORE Imaging: an OCT-IVUS Imaging Substudy of RESTORE Trial
Status: RECRUITING
Conditions: Acute Coronary Syndrome (ACS)
Interventions: DEVICE: Drug-coated balloon|DRUG: Guideline-directed medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research Study to Assess New Chikungunya and Zika Vaccines in Healthy Adults in Mexico.
Status: COMPLETED
Conditions: Chikungunya|Zika
Interventions: BIOLOGICAL: CHIK low dose|BIOLOGICAL: CHIK mid dose|BIOLOGICAL: CHIK high dose|BIOLOGICAL: ZIKA low dose|BIOLOGICAL: ZIKA mid dose|BIOLOGICAL: ZIKA high dose|BIOLOGICAL: Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics of High-dose Ceftobiprole in Community-acquired Pneumonia Under Mechanical Ventilation.
Status: UNKNOWN
Conditions: Pneumonia
Interventions: DRUG: Treatment with high-dose ceftobiprole (500mg loading dose followed by 2.5g under continuos infusion).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Searching for the Perfect Oil to Protect the Perineum: A Randomized-Controlled, Double-Blind Trial
Status: UNKNOWN
Conditions: Second Stage of Labor
Interventions: OTHER: perineal massage with Wheat Germ Oil during the second stage of labor|OTHER: perineal massage with almond oil during the second stage of labor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Electroacupuncture in Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel|Carpal Tunnel Syndrome|Pain|Pain Syndrome|Pain Syndrome Myofascial
Interventions: PROCEDURE: 8 sessions of electroacupuncture to the upper limb with carpal tunnel syndrome
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of BioBlock COVID-19 Nasal Spray Containing Anti-SARS-CoV-2 Antibodies Derived From Bovine Colostrum
Status: COMPLETED
Conditions: SARS-COV2 Infection|Covid19
Interventions: OTHER: Nasal Spray Containing Anti-SARS-CoV-2 Antibodies Derived from Bovine Colostrum
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evolution of the Lymphocyte Phenotype in Patients With Infection in Intensive Care Unit
Status: NOT_YET_RECRUITING
Conditions: Patients Undergoing Esophagectomy|Patients With Severe Polytrauma|Patients With Severe Neurological Lesion|Patients With Abdominal Infection
Interventions: PROCEDURE: Lymphocyte Phenotyping Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Compression Aided Management of Edema in Patients With C3 Venous Disease
Status: UNKNOWN
Conditions: Chronic Venous Disease
Interventions: DEVICE: Anti-embolism Knee High Stocking|DEVICE: 20-30 Knee High Compression Stocking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of GHRH on Sleep Promotion and Endocrine Regulation in Service Members Who Sustained a Traumatic Brain Injury and Have Current Insomnia
Status: WITHDRAWN
Conditions: Sleep Disorder|Traumatic Brain Injury
Interventions: DRUG: Tesamorelin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MabThera (Rituximab) Plus Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia.
Status: COMPLETED
Conditions: Lymphocytic Leukemia, Chronic
Interventions: DRUG: rituximab [MabThera/Rituxan]|DRUG: chlorambucil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety, Tolerability and Efficacy of KP-413 in Subjects With Atopic Dermatitis(AD)
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: KP-413 Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Intranasal Insulin in Children and Young Adults at Risk of Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: BIOLOGICAL: Intranasal insulin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: REGEnLIFE RGn530 - Feasibility Pilot
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DEVICE: Photobiomodulation REGEnLIFE RGn530 device|DEVICE: SHAM REGEnLIFE RGn530 device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Camrelizumab in Combination With Nb-Paclitaxel in Patients With Advanced or Metastatic NSCLC
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Camrelizumab|DRUG: nb-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical, Patient-centered Outcomes and Laser Doppler Flowmetry Using Two Types of SCTG
Status: COMPLETED
Conditions: Gingival Recession, Generalized
Interventions: PROCEDURE: de-epithelized (DE) SCTG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extended Evaluation of PROCHYMAL® Adult Human Stem Cells for Treatment-Resistant Moderate-to-Severe Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Placebo|DRUG: PROCHYMAL adult human mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interactions Between DWP14012 and DWC202202 in Healthy Subjects
Status: COMPLETED
Conditions: Drug Drug Interaction
Interventions: DRUG: DWP14012|DRUG: DWC202202|DRUG: DWC202203
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anesthetic Efficacy of Gow-Gates Versus Conventional Inferior Alveolar Nerve Block Techniques
Status: UNKNOWN
Conditions: Anesthesia; Reaction|Pain
Interventions: PROCEDURE: Type of block injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Pre-Operative Prehabilitation Program Women With Gynecological Cancer
Status: NOT_YET_RECRUITING
Conditions: Gynecologic Cancer|Prehabilitation
Interventions: OTHER: Prehabilition program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Naftopidil for the Double-J Stent Discomfort
Status: COMPLETED
Conditions: Disorder of Urinary Stent
Interventions: DRUG: Naftopidil|DRUG: Placebo for Naftopidil|DRUG: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Influence of Desensitizing Treatments on the Pulp Inflammatory Response in Bleached Teeth
Status: COMPLETED
Conditions: Pulp Inflammation
Interventions: OTHER: Whiteness HP 35%|DEVICE: Whiteness HP 35% + LASER|OTHER: Whiteness HP 35% + CPP|OTHER: Whiteness HP 35% + NANO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Satiety and Alcohol Challenge
Status: NOT_YET_RECRUITING
Conditions: Alcohol Drinking
Interventions: DIETARY_SUPPLEMENT: Dietary Fiber + Green Tea Extract|OTHER: Alcohol|OTHER: Aspartame Placebo Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Study in Young Adults to Examine the Kinetics of Changes in the B-cell Repertoire Following TIV Immunization
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: 2011-2012 Fluzone IIV3 (IM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SPR720 as Compared With Placebo for the Treatment of Participants With Mycobacterium Avium Complex (MAC) Pulmonary Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Nontuberculous Mycobacterial Pulmonary Disease (NTM-PD)
Interventions: DRUG: Placebo|DRUG: SPR720 500 mg|DRUG: SPR720 1000 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectivity of Bispectral Index Monitoring in Cases of Endoscopic Retrograde Cholangiopancreatography
Status: UNKNOWN
Conditions: Sedoanalgesia
Interventions: DEVICE: The bispectral index (BIS) monitoring|BEHAVIORAL: Ramsay Sedation Scale (RSS) Score monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility of a Digital Goals-of-Care Decision Aid for Clinicians and Families of Patients With SABI
Status: RECRUITING
Conditions: Hemorrhagic Stroke, Intracerebral|Acute Ischemic Stroke|Traumatic Brain Injury
Interventions: BEHAVIORAL: Web/mobile/tablet-based digital decision aid + communication (DA+C) tool
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Fluoxetine to Prevent Relapse and Enhance Psychological Recovery in Women With Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa|Eating Disorders
Interventions: DRUG: Fluoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ethnicity and Onset of Cardiovascular Disease: A CALIBER Study
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm|Coronary Heart Disease|Sudden Cardiac Death|Intracerebral Haemorrhage|Heart Failure|Ischemic Stroke|Myocardial Infarction|Stroke|Peripheral Arterial Disease|Stable Angina Pectoris|Subarachnoid Haemorrhage|Transient Ischemic Attack|Unstable Angina|Cardiac Arrest
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Efficacy Trial of Low Dose All-trans Retinoic Acid in Patients With Primary Sclerosing Cholangitis
Status: TERMINATED
Conditions: Cholangitis, Sclerosing
Interventions: DRUG: All-trans retinoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety and Performance of the ProstaCare Water Electrolysis System in Relieving Symptoms of BPH.
Status: TERMINATED
Conditions: Benign Prostatic Hyperplasia
Interventions: DEVICE: prostaFix System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROCLAIM-CX-188: A Trial to Find Safe and Active Doses of an Investigational Drug CX-188 for Patients With Solid Tumors
Status: WITHDRAWN
Conditions: Solid Tumor, Adult
Interventions: DRUG: CX-188
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and Carboplatin or Ifosfamide in Treating Patients With Newly Diagnosed, Persistent or Recurrent Uterine, Ovarian, Fallopian Tube, or Peritoneal Cavity Cancer
Status: UNKNOWN
Conditions: Mixed Mesodermal (Mullerian) Tumor|Ovarian Carcinosarcoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Stage I Ovarian Cancer AJCC v6 and v7|Stage IA Fallopian Tube Cancer AJCC v6 and v7|Stage IA Ovarian Cancer AJCC v6 and v7|Stage IA Uterine Sarcoma AJCC v7|Stage IB Fallopian Tube Cancer AJCC v6 and v7|Stage IB Ovarian Cancer AJCC v6 and v7|Stage IB Uterine Sarcoma AJCC v7|Stage IC Fallopian Tube Cancer AJCC v6 and v7|Stage IC Ovarian Cancer AJCC v6 and v7|Stage IC Uterine Sarcoma AJCC v7|Stage II Ovarian Cancer AJCC v6 and v7|Stage IIA Fallopian Tube Cancer AJCC v6 and v7|Stage IIA Ovarian Cancer AJCC V6 and v7|Stage IIA Uterine Sarcoma AJCC v7|Stage IIB Fallopian Tube Cancer AJCC v6 and v7|Stage IIB Ovarian Cancer AJCC v6 and v7|Stage IIB Uterine Sarcoma AJCC v7|Stage IIC Fallopian Tube Cancer AJCC v6 and v7|Stage IIC Ovarian Cancer AJCC v6 and v7|Stage IIIA Fallopian Tube Cancer AJCC v7|Stage IIIA Ovarian Cancer AJCC v6 and v7|Stage IIIA Primary Peritoneal Cancer AJCC v7|Stage IIIA Uterine Sarcoma AJCC v7|Stage IIIB Fallopian Tube Cancer AJCC v7|Stage IIIB Ovarian Cancer AJCC v6 and v7|Stage IIIB Primary Peritoneal Cancer AJCC v7|Stage IIIB Uterine Sarcoma AJCC v7|Stage IIIC Fallopian Tube Cancer AJCC v7|Stage IIIC Ovarian Cancer AJCC v6 and v7|Stage IIIC Primary Peritoneal Cancer AJCC v7|Stage IIIC Uterine Sarcoma AJCC v7|Stage IV Fallopian Tube Cancer AJCC v6 and v7|Stage IV Ovarian Cancer AJCC v6 and v7|Stage IV Primary Peritoneal Cancer AJCC v7|Stage IVA Uterine Sarcoma AJCC v7|Stage IVB Uterine Sarcoma AJCC v7|Uterine Carcinosarcoma
Interventions: DRUG: Carboplatin|DRUG: Ifosfamide|DRUG: Paclitaxel|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention For AYAS With Cancer Risk Syndromes
Status: RECRUITING
Conditions: Cancer Risk Syndrome
Interventions: BEHAVIORAL: AYA-RISE Adolescents and Young Adults Risk Information and Screening Education|BEHAVIORAL: Standard clinical visit for genetic counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Different Amputation Levels
Status: COMPLETED
Conditions: Amputee|Plantar Pressure Distrubution|Balance
Interventions: OTHER: Bipedal with open eyes|OTHER: Bipedal with closed eyes|OTHER: Bipedal with open eyes and with platform|OTHER: Bipedal with closed eyes and with platform
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Effect of Output on New Adhesives
Status: COMPLETED
Conditions: Ileostomy - Stoma
Interventions: OTHER: Adhesive strip A|OTHER: Adhesive strip B|OTHER: Adhesive strip C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vitamin D Supplementation in Patients With Depression
Status: UNKNOWN
Conditions: Depression
Interventions: DIETARY_SUPPLEMENT: vitamin D supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Combination Chemotherapy Regimens in Treating Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFIRI regimen|DRUG: FOLFOX regimen|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Evaluate the Safety and Immunogenicity of Recombinant HIV-1 Envelope Antigen in Children Born to HIV-Infected Mothers
Status: COMPLETED
Conditions: HIV Infections|HIV Seronegativity
Interventions: BIOLOGICAL: rgp120/HIV-1MN|BIOLOGICAL: rgp120/HIV-1 SF-2|BIOLOGICAL: Placebo version of rgp120/HIV-1MN|BIOLOGICAL: Placebo version of rgp120/HIV-1SF2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dexmetomidine and Remifentanil Used for Controlled Hypotension in Septorhinoplasty Surgery on Cardiac Electrophysiology: Prospective Randomized Study
Status: NOT_YET_RECRUITING
Conditions: Rhinoplasty Surgery
Interventions: DRUG: Dexmedetomidine|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Depolarization and Repolarisation Activity During Cardiac Arrhythmia Using a Novel Monophasic Action Potential Catheter
Status: COMPLETED
Conditions: Atrial Fibrillation|Ventricular Fibrillation|Junctional Tachycardia
Interventions: DEVICE: Cardiac chambers mapping with MAP 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC