pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Taking Care of Her Program in Patients With Stage III or IV Ovarian Cancer and Spouse Caregivers
Status: COMPLETED
Conditions: Caregiver|Stage IIIA Ovarian Cancer|Stage IIIB Ovarian Cancer|Stage IIIC Ovarian Cancer|Stage IV Ovarian Cancer
Interventions: BEHAVIORAL: Telephone-Based Intervention|OTHER: Caregiver-Assisted Training|OTHER: Questionnaire Administration|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Evaluating the Effect of Albiglutide on Gallbladder Emptying in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Albiglutide 50 mg|DRUG: Placebo|DRUG: CCK (Kinevac)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi Center Clinical Trial of Rph With the Simplified Milligan-Morgan Surgery on Treatment of Mixed Hemorrhoids
Status: UNKNOWN
Conditions: Mixed Hemorrhoids
Interventions: PROCEDURE: RPH with the simplified Milligan-Morgan|PROCEDURE: PPH with the simplified Milligan-Morgan|PROCEDURE: RPH|PROCEDURE: PPH|PROCEDURE: Milligan-Morgan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of CB-01-11 200mg Tablets in Infectious Diarrhoea
Status: COMPLETED
Conditions: Infectious Diarrhoea
Interventions: DRUG: 400 mg Rifamycin SV dosage|DRUG: 800 mg Rifamycin SV dosage|DRUG: 1200 mg Rifamycin SV dosage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of RAD001 + TACE in Localized Unresectable HCC
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: everolimus|DRUG: everolimus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACT for Syndromic and Subsyndromic Depression in Bipolar Disorder
Status: RECRUITING
Conditions: Bipolar Disorder
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy|OTHER: Bipolar Disorder Psychoeducation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Evaluation of the Dose of Erythropoietins Trial
Status: COMPLETED
Conditions: Kidney Failure, Chronic
Interventions: DRUG: Erythropoiesis Stimulating Agents (ESAs): epoetin alfa, beta or any other epoetin in equivalent dose.|DRUG: Erythropoiesis Stimulating Agents (ESAs): epoetin alfa, beta or any other epoetin in equivalent dose.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluation the Safety and Efficacy of Hormone Replacement Therapy With North Star Compared to Levothyroxine in Patients With Primary Hypothyroidism
Status: ENROLLING_BY_INVITATION
Conditions: Hypothyroidism
Interventions: DRUG: North Star|DRUG: Levothyroxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PerLE (Peroneus Longus Evaluation): A Study Evaluating the Efficacy of Injection of Dysport in Peroneus Longus in Equinus Foot Deformity in Children With Cerebral Palsy
Status: UNKNOWN
Conditions: Equinus Foot Deformity in Children With Cerebral Palsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optimization and Multi-Site Feasibility of Yoga for Chronic Pain in People in YOGAMAT-II - Phase II
Status: RECRUITING
Conditions: Opioid Use|Chronic Pain
Interventions: BEHAVIORAL: Weekly Yoga Classes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: EASE TRICUSPID Expertise-based Assessment Study on Clinical Efficacy of Contour 3D® in TRICUSPID Valve Annuloplasty
Status: COMPLETED
Conditions: Tricuspid Valve Insufficiency
Interventions: PROCEDURE: Tricuspid valve repair|PROCEDURE: Left-sided heart surgery|DEVICE: Contour 3D Tricuspid Annuloplasty Ring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cross-sectional Case and Control Study on Quality of Life, Appearance and Functions in PTC Via Different Surgical Approach
Status: RECRUITING
Conditions: Papillary Thyroid Carcinoma|Thyroid Cancer
Interventions: PROCEDURE: Thyroid lobectomy via trans-axillary approach|PROCEDURE: Thyroid lobectomy via open approach
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Acute and Chronic Ligament and Tendon Injuries With Platelet Rich Plasma
Status: COMPLETED
Conditions: Tendinopathy
Interventions: PROCEDURE: Ultrasound-guided platelet-rich-plasma (PRP) injection|PROCEDURE: Ultrasound-guided dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Carbon Dioxide Insufflation and Appendix on the Restoration of Intestinal Microecology After Colonoscopy.
Status: ACTIVE_NOT_RECRUITING
Conditions: Colonoscopy|Gastrointestinal Microbiome|Appendix|Carbon Dioxide Insufflation
Interventions: OTHER: Carbon dioxide insufflated during colonoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Biomarkers for Early Detection of Ovarian Cancer Using Uterine Lavage
Status: RECRUITING
Conditions: Ovarian Cancer|Ovarian Carcinoma|Fallopian Tube Cancer|Primary Peritoneal Carcinoma|Serous Cystadenocarcinoma
Interventions: PROCEDURE: Uterine lavage|PROCEDURE: Blood sample|DEVICE: Uterine lavage catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intranasal ALN-RSV01 Administered to Adult Volunteers Experimentally Inoculated With Respiratory Syncytial Virus
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: ALN-RSV01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Weight Cycling on Hyperandrogenemia and Insulin Resistance in Polycystic Ovary Syndrome
Status: NOT_YET_RECRUITING
Conditions: Polycystic Ovary Syndrome
Interventions: OTHER: Adjusting dietary structure + exercise + behavioral intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Immune Mechanisms After Radiofrequency Ablation of Pulmonary Metastases From Colorectal Cancer Origin
Status: COMPLETED
Conditions: Immune Evasion, Tumor|Neoplastic Cells, Circulating|Circulating Tumor Cell|Pulmonary Metastasis|Colo-rectal Cancer
Interventions: RADIATION: RFA interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of Ezetimibe (SCH 058235/MK-0653) Plus Atorvastatin or Simvastatin in Homozygous Familial Hypercholesterolemia (P01417/MK-0653-019)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Ezetimibe|DRUG: Atorvastatin|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Bile Acid Supplementation in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Progressive Multiple Sclerosis
Interventions: DRUG: Tauroursodeoxycholic Acid|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Opioid-free Analgesia and Anesthesia on the Quality of Postoperative Recovery and Nausea Vomit in Patients Receiving Laparoscopic Sleeve Gastrectomy
Status: RECRUITING
Conditions: Opioid-Free Anesthesia|Laparoscopic Sleeve Gastrectomy|Postoperative Vomiting|Postoperative Recovery
Interventions: DRUG: Opioid-free Analgesics (esketamine, dexmedetomidine)|DRUG: Opioid Anesthetics (sufentanil and remifentanil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: : A Prospective Study Investigating the Use of the Eko CORE and Eko DUO Electronic Stethoscopes in Pediatric Patients.
Status: COMPLETED
Conditions: Heart Murmurs
Interventions: DEVICE: Use of EKO Core and EKO Duo electronic stethoscopes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of Amniotic Membrane Patch to Treat Postoperative Atrial Fibrillation
Status: WITHDRAWN
Conditions: Atrial Fibrillation
Interventions: BIOLOGICAL: Amniotic Membrane Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Pharmacokinetic Comparability Between AZD7442 Co-formulation (AZD8895 + AZD1061) vs AZD8895 and AZD1061 Individually in Adult Healthy Participants
Status: COMPLETED
Conditions: Corona Virus Disease
Interventions: BIOLOGICAL: AZD7442|BIOLOGICAL: AZD8895 (clonal cell line material)|BIOLOGICAL: AZD1061 (clonal cell line material)|BIOLOGICAL: AZD8895 (cell pool material)|BIOLOGICAL: AZD1061 (cell pool material)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Amisulpride Vs Olanzapine-Fluoxetine Combination in Post-Schizophrenic Depression
Status: UNKNOWN
Conditions: Post-Schizophrenic Depression
Interventions: DRUG: Amisulpride|DRUG: Olanzapine-Fluoxetine Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Physiopathological Mechanisms and Results of Treatment With Bronchial Thermoplasty in Severe Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: DEVICE: ALAIR Catheter. Radiofrequency system.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Menadione Topical Lotion in Treating Skin Discomfort and Psychological Distress in Patients With Cancer Receiving Panitumumab, Erlotinib Hydrochloride, or Cetuximab
Status: ACTIVE_NOT_RECRUITING
Conditions: Dermatologic Complications|Malignant Neoplasm|Pain
Interventions: DRUG: menadione topical lotion|OTHER: placebo|OTHER: questionnaire administration|PROCEDURE: management of therapy complications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep Positional Trainer for Positional Sleep Apnea After Mandibular Advancement Device (MAD) Therapy
Status: COMPLETED
Conditions: Positional Sleep Apnea|Mandibular Advancement Device
Interventions: DEVICE: Sleep Position Trainer (SPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Feasibility Study of the FARAPULSE Endocardial Multi Ablation System in the Treatment of Persistent Atrial Fibrillation
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation
Interventions: DEVICE: Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Pain, Patient Reported Outcomes and Complementary and Integrative Health
Status: COMPLETED
Conditions: Chronic Musculoskeletal Pain
Interventions: OTHER: Practitioner-delivered CIH therapies (acupuncture, therapeutic massage, chiropractic care) as received in VHA and community practice settings|OTHER: Self-care CIH therapies (yoga, Tai Chi/Qigong , meditation) as received in VHA and community practice settings|OTHER: Combination of practitioner-delivered and self-care CIH therapies (described above) as received in VHA and community practice settings
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs
Status: RECRUITING
Conditions: Liver Diseases|Liver Cirrhosis|Acute-On-Chronic Liver Failure|Liver Transplant; Complications
Interventions: OTHER: Observational Protocol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety and Efficacy Study of Bimatoprost in Men With Androgenic Alopecia (AGA)
Status: COMPLETED
Conditions: Alopecia|Alopecia, Androgenetic|Baldness
Interventions: DRUG: Bimatoprost Solution 1|DRUG: Bimatoprost Solution 2|DRUG: Bimatoprost Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combining Immunotherapy Salvage Surgery & IORT Tx Persistent/Recurrent Head & Neck Cancer
Status: RECRUITING
Conditions: Head and Neck Carcinoma of Unknown Primary|Locally Recurrent Head and Neck Squamous Cell Carcinoma|Recurrent Laryngeal Squamous Cell Carcinoma|Recurrent Oral Cavity Squamous Cell Carcinoma|Recurrent Pharyngeal Squamous Cell Carcinoma|Resectable Head and Neck Squamous Cell Carcinoma
Interventions: RADIATION: External Beam Radiation Therapy|RADIATION: Intraoperative Radiation Therapy|BIOLOGICAL: Pembrolizumab|OTHER: Quality-of-Life Assessment|PROCEDURE: Salvage Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of ASF-1096 Cream 0.5% in the Treatment of Discoid Lupus Erythematosus (DLE) Lesions
Status: COMPLETED
Conditions: Discoid Lupus Erythematosus
Interventions: DRUG: ASF 1096 0.5 % cream applied twice daily|DRUG: Cream vehicle for ASF 1096 cream applied twice daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Evaluation of a Glucagon Sensitivity Test in Individuals With and Without Hepatic Steatosis
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease|Glucagon Resistance|Type 1 Diabetes|Obesity
Interventions: DIAGNOSTIC_TEST: Glucagon Sensitivity test consisting of an amino acid tolerance test and a bolus infusion of glucagon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Linezolid Dosing Strategies in Drug-Resistant TB
Status: RECRUITING
Conditions: Tuberculosis, Multidrug-Resistant|Tuberculosis|Tuberculosis, Pulmonary
Interventions: DRUG: Linezolid 600 mg|DRUG: Linezolid 1200 mg (QD)|DRUG: Linezolid 1200 mg (TIW)|DRUG: Bedaquiline 200 mg|DRUG: Bedaquiline 100 mg|DRUG: Delamanid 300 mg|DRUG: Clofazimine 300 mg|DRUG: Clofazimine 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-escalation of Cellistem-OA in Patients With Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: umbilical cord derived-mesenchymal stromal cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Apomorphine Subcutaneous Infusion in Patients With Advanced Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Apomorphine hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Use of Indomethacin as Co-treatment in Women With Preterm Labor and High Risk of Intraamniotic Inflammation
Status: COMPLETED
Conditions: Preterm Labor With Intact Membranes
Interventions: DRUG: indomethacin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of Intravesical VAX014 for Instillation in Subjects With Non-Muscle Invasive Bladder Cancer
Status: COMPLETED
Conditions: Urothelial Carcinoma of the Urinary Bladder
Interventions: DRUG: VAX014
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vein of Marshall Ethanol Infusion for Persistent Atrial Fibrillation
Status: COMPLETED
Conditions: Ventricular Tachycardia|Atrial Fibrillation
Interventions: DRUG: Ethanol|PROCEDURE: Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Interactions Between Amlodipine Besylate/Valsartan and Atorvastatin in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: combination administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stellate Ganglion Block on Gastroesophageal Reflux Disease
Status: NOT_YET_RECRUITING
Conditions: Gastroesophageal Reflux Disease
Interventions: BEHAVIORAL: Rehabilitation therapy|PROCEDURE: Stellate ganglion block|DRUG: Lidocaine hydrochloride|PROCEDURE: Placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Bendamustine in Very Elderly Patients or Elderly Medically Non Fit Patients With Aggressive B-cell Lymphoma
Status: COMPLETED
Conditions: Aggressive Lymphoma
Interventions: DRUG: Bendamustine and subcutaneous rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Efficacy and Safety of Tacrolimus Capsules and Cyclophosphamide Injection in Treatment of Lupus Nephritis
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: DRUG: Tacrolimus capsules|DRUG: Cyclophosphamide injections|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab Combined With Apatinib, Etoposide and Cisplatin Treat Small-cell Lung Cancer.
Status: UNKNOWN
Conditions: Lung Neoplasm|Small Cell Lung Cancer|PD-1 Inhibitors
Interventions: DRUG: Camrelizumab combined with Apatinib, Etoposide and Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Topical Olive Oil in Prevention and Management of Radiation Induced Oral Mucositis
Status: COMPLETED
Conditions: Radiation Mucositis|Oral Mucositis (Ulcerative) Due to Radiation|Radiation-Induced Mucositis
Interventions: OTHER: Topical Olive Oil|OTHER: Sodium bicarbonate 5% solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Replacement of Nebulised Ipratropium With Inhaled Tiotropium in Stable Chronic Obstructive Pulmonary Disease (COPD)
Status: WITHDRAWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Inhaled Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Neoadjuvant Tislelizumab Combined With Chemotherapy in Locally Advanced MSS Rectal Cancer
Status: RECRUITING
Conditions: Rectal Cancer|Rectal Cancer Stage II|Rectal Cancer Stage III
Interventions: DRUG: Tislelizumab combined with chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TQB2223 Injection in Combination With Penpulimab in Patients With Advanced Cancers
Status: RECRUITING
Conditions: Advanced Cancer
Interventions: DRUG: TQB2223 injection+ Penpulimab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Mirikizumab (LY3074828) in Participants With Moderately to Severely Active Ulcerative Colitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Ulcerative Colitis|Ulcerative Colitis Chronic
Interventions: DRUG: Mirikizumab|DRUG: Mirikizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Prove Non-inferior Immunogenicity of Grippol Quadrivalent Compared to Grippol Plus
Status: COMPLETED
Conditions: Influenza|Influenza A|Influenza, Human|Influenza Type B|Flu|Influenza A H3N2|Influenza A H1N1|Influenza Epidemic|Flu, Human|Acute Respiratory Infection|Vaccine Reaction
Interventions: BIOLOGICAL: Grippol Quadrivalent|BIOLOGICAL: Grippol Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immune Response of Novartis of MenACWY Conjugate Vaccine When Given to Healthy Children
Status: COMPLETED
Conditions: Meningococcal Infections
Interventions: BIOLOGICAL: MenACWY-CRM|BIOLOGICAL: MenACWY-CRM|BIOLOGICAL: Licensed meningococcal ACWY vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Acute Responses to Arm-Crank Exercise on Cardiovascular Function of Patients With Peripheral Artery Disease
Status: ENROLLING_BY_INVITATION
Conditions: Intermittent Claudication|Cardiovascular Diseases|Blood Pressure|Endothelial Dysfunction|Peripheral Arterial Disease
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Image Guided Therapy in the Treatment of Gliomas
Status: TERMINATED
Conditions: Glioma
Interventions: PROCEDURE: Diffusion-weighted magnetic resonance imaging|PROCEDURE: Perfusion-weighted magnetic resonance imaging|PROCEDURE: Functional magnetic resonance imaging|PROCEDURE: Magnetic resonance spectroscopic imaging|PROCEDURE: Therapeutic conventional surgery|PROCEDURE: Quality-of-life assessment|PROCEDURE: Radiation therapy treatment planning/simulation|PROCEDURE: Intensity-modulated radiation therapy|OTHER: Questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cold Snare Piecemeal Resection vs Cold Snare Endoscopic Mucosal Resection
Status: ENROLLING_BY_INVITATION
Conditions: Colon Cancer|Colon Polyp|Colon Adenoma|Serrated Polyp
Interventions: PROCEDURE: Cold Snare Piecemeal Resection (CSPR)|PROCEDURE: Cold Snare Endoscopic Mucosal Resection (Cold EMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multi-Channel Gastric Electrical Stimulation for the Treatment of Gastroparesis
Status: COMPLETED
Conditions: Gastric Stasis
Interventions: DEVICE: Enterra Multi-Channel Phased Gastric Pacemaker (MGP-1)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nonstented Stump-closed vs Duct-to-Mucosa Pancreaticojejunostomy After Pancreaticoduodenectomy
Status: COMPLETED
Conditions: Pancreatic Neoplasms|Biliary Tract Neoplasms|Pancreatitis, Chronic|Duodenal Neoplasms
Interventions: PROCEDURE: pancreaticojejunostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vibration Therapy Over Neck Myofascial Trigger Points
Status: COMPLETED
Conditions: Myofascial Trigger Point Pain|Neck Pain
Interventions: DEVICE: Shindo® vibration mattress
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of NSAID Use in the Acute Phase of Skeletally Immature Bone Healing: A Prospective Study
Status: COMPLETED
Conditions: Fractures
Interventions: DRUG: Acetaminophen|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine for COVID-19
Status: TERMINATED
Conditions: COVID-19, Hydroxychloroquine Sulfate
Interventions: DRUG: Hydroxychloroquine Sulfate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Regional Technics In Knee Artroplasty
Status: COMPLETED
Conditions: Postoperative Analgesia|Anesthesia; Functional
Interventions: PROCEDURE: intratechal (subarachnoidal )injection|PROCEDURE: lombar plexus and sciatic nerve injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Bewteen DopaSnap® (Cabidopa/Levopdoap 25/100 mg Tablet) and Carbidopa/Levodopa 25/100 mg Tablet (Actavis)
Status: COMPLETED
Conditions: Other
Interventions: DRUG: DopaSnap®|DRUG: RDL of CD-LD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: BacterioPHAGE for Gastrointestinal Health 2 Study
Status: COMPLETED
Conditions: Mild Gastrointestinal Symptoms in Healthy Adults
Interventions: DIETARY_SUPPLEMENT: Bifidobacterium animals subsp. lactis BL04+PreforPro|DIETARY_SUPPLEMENT: Bifidobacterium animals subsp. lactis BL04|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Six-week Study Comparing the Efficacy and Safety of Tiotropium Plus Formoterol to Salmeterol Plus Fluticasone in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Test: Tiotropium 18 µg per day (one inhalation capsule) plus 12 µg formoterol twice daily (two times one inhalation capsule)|DRUG: Reference: Salmeterol MDI 50 µg (2 puffs of 25 µg each) b.i.d., plus fluticasone propionate MDI 500 µg (2 puffs of 250 µg each) b.i.d.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Ph II CHOP+Velcade in Mediastinal LBCL
Status: TERMINATED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: bortezomib|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of a Commercially-available Oil Rinse Product (PerioPull™) on Markers of Dental Health
Status: RECRUITING
Conditions: Oral Health
Interventions: DIETARY_SUPPLEMENT: PerioPull™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Nebulised Hypertonic Saline (3%) Among Children With Bronchiolitis.
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: DRUG: L-Epinephrine and Normal Saline (0.9%)|DRUG: L-Epinephrine and Hypertonic Saline (3%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of HemaMax™ (rHuIL-12) as Radiation Countermeasure
Status: COMPLETED
Conditions: Hematopoietic Syndrome Due to Acute Radiation Syndrome
Interventions: BIOLOGICAL: HemaMax|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Methylated Gene Promoter Status
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: Cilengitide|DRUG: Temozolomide|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual IntraVenous Thrombolysis Approach (DIVA) in Patients With Medium-vessel-occlusion Strokes: a Retrospective Study
Status: COMPLETED
Conditions: Acute Ischemic Stroke Due to Medium-vessel-occlusion
Interventions: DRUG: alteplase|DRUG: Alteplase + possible complementary IVT with tenecteplase
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Unresectable Stage IIIA/IIIB Non-small Cell Lung Cancer (NSCLC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Nivolumab|DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anterior Shoulder Instability Treated With a Semitendinosus Subscapular Sling Procedure
Status: ACTIVE_NOT_RECRUITING
Conditions: Anterior Shoulder Dislocation|Joint Instability
Interventions: PROCEDURE: subscapular sling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Unicentric Retrospective Analysis of a Cohort of 602 Young Adult and Adolescent Patients (AJA), Aged 15 to 30 Years, With Haematological Malignancies, and Managed Between 2000 and 2016
Status: COMPLETED
Conditions: Malignant Haemopathies|Acute Leukemia|Non-hodgkin Lymphoma|Hodgkin Lymphoma
Interventions: DRUG: administered therapeutic regimens
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adipose Tissue Derived Stem Cell Based Hair Restoration Therapy for Androgenetic Alopecia
Status: COMPLETED
Conditions: Combination of SVF and PRP for Androgenetic Alopecia
Interventions: DRUG: stem cells|DRUG: platelet rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate How Safe Long-term Treatment With Pozelimab + Cemdisiran Combination Therapy is and How Well it Works.
Status: RECRUITING
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: Pozelimab|DRUG: Cemdisiran
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Therapeutic Vaccine TG4040 Combined With Pegylated Interferon and Ribavirin in Chronic HCV Patients
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection
Interventions: DRUG: pegylated interferon and ribavirin|BIOLOGICAL: TG4040 + SOC|BIOLOGICAL: TG4040 + SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of an MF59-Adjuvanted Quadrivalent Influenza Vaccine Compared to Non-influenza Vaccine Comparator in Adults ≥ 65 Years of Age
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: MF59-adjuvanted Quadrivalent Subunit Inactivated Egg-derived Influenza Vaccine (aQIV)|BIOLOGICAL: Non-Influenza Comparator (Boostrix)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Tranexamic Acid Based on Pharmacokinetics in Pediatric Patients Undergoing Craniosynostosis Surgery: Randomized Controlled Trial
Status: COMPLETED
Conditions: Craniosynostosis Patients Undergoing Distraction Osteotomy
Interventions: DRUG: Tranexamic Acid|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Tamoxifen in Women With Breast Cancer and in Women at High-Risk of Breast Cancer Who Are Receiving Venlafaxine, Citalopram, Escitalopram, Gabapentin, or Sertraline
Status: COMPLETED
Conditions: Breast Cancer|Depression|Hot Flashes|Psychosocial Effects of Cancer and Its Treatment
Interventions: DRUG: citalopram hydrobromide|DRUG: escitalopram oxalate|DRUG: gabapentin|DRUG: sertraline hydrochloride|DRUG: tamoxifen citrate|DRUG: venlafaxine|GENETIC: molecular genetic technique|OTHER: high performance liquid chromatography|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: adjuvant therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Parent-Adolescent Interpersonal Processes in the Science of Behavior Change
Status: COMPLETED
Conditions: Sleep Deprivation|Adolescent Behavior
Interventions: BEHAVIORAL: Parent Behavior Change Intervention (PBC-I) and Transdiagnostic Sleep and Circadian Intervention (TranS-C)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Epidural Fentanyl and Clonidine for Breakthrough Pain
Status: COMPLETED
Conditions: Labor Pain
Interventions: DRUG: Clonidine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Trial to Evaluate the Efficacy and Safety of Luphere Depot Inj. 3.75mg(Leuprolide Acetate 3.75mg) in Patients With Precocious Puberty
Status: COMPLETED
Conditions: Central Precocious Puberty
Interventions: DRUG: Luphere depot 3.75mg(Leuprolide acetate 3.75mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemigatinib + Afatinib in Advanced Refractory Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|Unresectable Solid Tumor|Metastatic Solid Tumor|Cholangiocarcinoma
Interventions: DRUG: Afatinib|DRUG: Pemigatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Actual Use, Open-label Study Assessing Usability of Remote Assist to Program Cochlear Implant Recipients
Status: COMPLETED
Conditions: Hearing Loss, Sensorineural|Hearing Loss, Bilateral
Interventions: DEVICE: Cochlear Implant (CI)-CI500 series, CI600 series or Freedom series cochlear implants
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Electronic Device Implantation Through Remote Guidance
Status: ACTIVE_NOT_RECRUITING
Conditions: Telemedicine|Heart Failure|Defibrillators
Interventions: OTHER: interventional cardiology procedures with proctoring system|OTHER: interventional cardiology procedures with engineer in the electrophysiology laboratory
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Kimura Versus Warshaw Technique for Laparoscopic Spleen-Preserving Distal Pancreatectomy
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Tumor, Benign|Pancreatic Neuroendocrine Tumor|Solid Pseudopapillary Tumor of the Pancreas
Interventions: PROCEDURE: Laparoscopic spleen-preserving distal pancreatectomy using the Kimura technique|PROCEDURE: Laparoscopic spleen-preserving distal pancreatectomy using the Warshaw technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Uterine Transposition: Feasibility Study
Status: COMPLETED
Conditions: Postoperative Complications|Intraoperative Complications|Tissue Damage|Ovarian Failure|Uterus Disorder
Interventions: PROCEDURE: Uterine transposition.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Red Grape Cells (RGC) Powder in Type 2 Diabetics
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Red Grape Cells (RGC)|DIETARY_SUPPLEMENT: Placebo (for Red Grape Cells (RGC))
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Sedation for Endoscopy With Propofol Versus Midazolam in Cirrhotics
Status: UNKNOWN
Conditions: Hepatic Encephalopathy
Interventions: DRUG: Propofol|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Trial of the Combination of Lenalidomide (Revlimid) and Nab-paclitaxel (Abraxane) in the Treatment of Relapsed/Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bare Metal Bifurcation Stent Clinical Trial in Humans
Status: COMPLETED
Conditions: Coronary Artery Disease|Myocardial Ischemia
Interventions: DEVICE: Medtronic Bifurcation Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Siltuximab and Spartalizumab in Patients With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Adenocarcinoma|Stage IV Pancreatic Cancer AJCC v8
Interventions: BIOLOGICAL: Siltuximab|BIOLOGICAL: Spartalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Long-term Effects of Oceanix™ on Resistance Training Adaptations
Status: COMPLETED
Conditions: Oxidative Stress|Muscle Strength|Resistance Training|Body Composition|Muscle Damage
Interventions: DIETARY_SUPPLEMENT: Oceanix|OTHER: Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Berotralstat Access to HAE Patients Previously Enrolled in Berotralstat Studies
Status: ACTIVE_NOT_RECRUITING
Conditions: Hereditary Angioedema|HAE
Interventions: DRUG: berotralstat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CART-19 FOR Relapsed/Refractory Acute Lymphoblastic Leukemia （ALL）
Status: UNKNOWN
Conditions: Leukemia, Lymphocytic, Acute
Interventions: BIOLOGICAL: CART-19 cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Acupuncture on the Natural Pregnancy in Patients With Recurrent Abortion
Status: COMPLETED
Conditions: Acupuncture|Recurrent Spontaneous Abortion|Ultrasound Therapy|Coagulation
Interventions: PROCEDURE: acupuncture|DRUG: routine aspirin and heparin treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Intratracheal Dexmedetomidine Versus Lidocaine in Eye Surgery
Status: COMPLETED
Conditions: Postoperative Complications
Interventions: DRUG: intratracheal saline|DRUG: intratracheal Dexmedetomidine|DRUG: intratracheal Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and Carboplatin for Patients With mCRPC and DNA-Repair Deficiencies
Status: TERMINATED
Conditions: Hormone-Resistant Prostate Cancer|Metastatic Prostate Carcinoma|Recurrent Prostate Carcinoma|Stage IV Prostate Cancer
Interventions: DRUG: Carboplatin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Risperidone in Situ Microparticle (ISM)® in Patients With Acute Schizophrenia
Status: COMPLETED
Conditions: Acute Schizophrenia
Interventions: DRUG: Risperidone ISM 75 mg|DRUG: Risperidone ISM 100 mg|DRUG: Placebo of Risperidone ISM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Outcome After Soft Tissue Realignment of the Tibial Insertion of the Patella Tendon
Status: COMPLETED
Conditions: Patella Dislocation
Interventions: PROCEDURE: Medialising insertion of patella tendon
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obturation Quality in Primary Molars
Status: COMPLETED
Conditions: Necrotic Primary Molars
Interventions: PROCEDURE: Rotary pulpectomy|PROCEDURE: Manual pulpectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study Of Gliadel, Concomitant Temozolomide And Radiation, Followed By Dose Dense Therapy With Temozolomide Plus Bevacizumab For Newly Diagnosed Malignant High Grade Glioma
Status: UNKNOWN
Conditions: Glioma
Interventions: DRUG: Temozolomide and Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study to Learn More About the Use of Darolutamide as a Part of a Combination Therapy in Belgian Men With Metastatic Hormone-Sensitive Prostate Cancer in Routine Medical Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Hormone-sensitive Prostate Cancer
Interventions: OTHER: Darolutamide (Nubeqa, BAY1841788) in combination with androgen deprivation therapy (ADT) and docetaxel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Eating Disorders: Online Self-help & Usual Treatment (TAU) vs TAU Only
Status: COMPLETED
Conditions: Anorexia Nervosa|Bulimia Nervosa|Binge Eating Disorder|Other Specified Feeding or Eating Disorder
Interventions: BEHAVIORAL: "Smart Eating" internet-based self-help programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of Enzastaurin Versus Placebo With Pemetrexed for Participants With Advanced or Metastatic Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: enzastaurin|DRUG: placebo|DRUG: pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Changing to DuoTrav® (Travoprost 0.004%/Timolol 0.5% BAK-Free Fixed Combination) From Prior Therapy
Status: TERMINATED
Conditions: Glaucoma
Interventions: DRUG: Travoprost/Timolol Maleate BAK-Free Fixed Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Feasibility of Medication Adherence Problem Solving for Hypertension
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension|Adherence, Medication
Interventions: BEHAVIORAL: Medication Adherence Problem Solving for Hypertension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I Study of Niraparib Administered Concurrently With Postoperative RT in Triple Negative Breast Cancer Patients
Status: RECRUITING
Conditions: Triple Negative Breast Cancer|Residual Disease
Interventions: DRUG: Niraparib|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Lot Consistency Trial)
Status: COMPLETED
Conditions: Hepatitis E
Interventions: BIOLOGICAL: Participants would receive 3 doses of Recombinant Hepatitis E Vaccine (Escherichia Coli) intramuscularly at 0, 1, 6 month.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Interrupting Sedentary Time on Glycemic Control in Older Overweight and Obese Adults
Status: COMPLETED
Conditions: Metabolic Syndrome|Diabetes|Aging
Interventions: OTHER: US|OTHER: IW|OTHER: CW
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Laparoscopic Spleen-Preserving No. 10 Lymph Node Dissection for Advanced Middle or Upper Third Gastric Cancer
Status: UNKNOWN
Conditions: Stomach Neoplasms
Interventions: PROCEDURE: D2 lymphadenectomy including No. 10|PROCEDURE: D2 lymphadenectomy excluding No. 10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT