pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effects of Rhus Coriaria L. on Serum Uric Acid Levels
Status: UNKNOWN
Conditions: Hyperuricemia
Interventions: DRUG: Rhus (Somagh)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Uncontrolled Study of ONO-4578 and ONO-4538 in Combination With Standard-of-care Docetaxel and Ramucirumab as Second-line Therapy in Patients With Advanced or Recurrent Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: ONO-4578|DRUG: ONO-4538|DRUG: Docetaxel|DRUG: Ramucirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 67Cu-SARTATE™ Peptide Receptor Radionuclide Therapy Administered to Pediatric Patients With High-Risk, Relapsed, Refractory Neuroblastoma
Status: RECRUITING
Conditions: Neuroblastoma|Relapsed Neuroblastoma|Refractory Neuroblastoma
Interventions: DRUG: 67Cu-SARTATE|DRUG: 64Cu-SARTATE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protein Supplementation and Exercise in Patients With FSH Muscular Dystrophy- a Randomized Placebo Controlled Study
Status: COMPLETED
Conditions: Facioscapulohumeral Muscle Dystrophy
Interventions: BEHAVIORAL: Regular exercise|DIETARY_SUPPLEMENT: Protein-carbohydrate supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Vitamin D in Parkinson's Disease (PD)
Status: COMPLETED
Conditions: Parkinson Disease|Accidental Falls
Interventions: DRUG: Vitamin D3|DIETARY_SUPPLEMENT: calcium|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of an Investigational Zoster Vaccine, in Subjects With a History of Herpes Zoster (V211-014)
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: zoster vaccine live (ZOSTAVAX™)|BIOLOGICAL: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Investigation of Mechanical Properties in Obesity.
Status: COMPLETED
Conditions: Body Fat Disorder|Obesity|Muscular Tone|Viscoelasticity
Interventions: DIAGNOSTIC_TEST: Myotonometric assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Intraoperative Nefopam on Acute Pain After Remifentanil Based Anesthesia
Status: UNKNOWN
Conditions: Cholecystitis
Interventions: DRUG: Nefopam|DRUG: Ketamine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Post-endodontic Pain After Root Canal Treatment With Two Rotary Systems : Mtwo & Safe-sider
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: PROCEDURE: mtwo rotary system|PROCEDURE: safe-sider rotary system|PROCEDURE: hand files
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Efficacy and Safety of MA-BUCY2 Conditioning in High-risk AML Patients Underwent Haplo-HSCT
Status: NOT_YET_RECRUITING
Conditions: Haploidentical Stem Cell Transplantation|Conditioning
Interventions: DRUG: MA-BUCY2|DRUG: BUCY2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide in Previously Treated Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia (CLL)|Small Lymphocytic Lymphoma
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency / and Sub-Study
Status: COMPLETED
Conditions: Heart Failure|Iron-deficiency
Interventions: DRUG: Ferric Carboxymaltose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Active Choice in the EHR to Promote Statin Therapy
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: BEHAVIORAL: Active choice|BEHAVIORAL: Passive choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Ivabradine on Exercise Capacity After Heart Transplantation
Status: UNKNOWN
Conditions: Cardiac Allograft Vasculopathy|Transplanted Heart Complication
Interventions: DRUG: Ivabradine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combining Lesinurad With Allopurinol in Inadequate Responders
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: Lesinurad|DRUG: Lesinurad|DRUG: Placebo|DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Crossover Trial Determining the Efficacy of Dry Powder Mannitol to Improve Lung Function in Subjects Aged 6-17 Years
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Inhaled Mannitol|DRUG: Inhaled Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 3-Dimensional Magnetic Imaging During Colonoscopy
Status: COMPLETED
Conditions: Any Symptom Requiring Colonoscopy
Interventions: DEVICE: Olympus ScopeGuide®, 3-dimentional magnetic imager
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hormone Therapy With or Without Docetaxel And Estramustine in Treating Patients With Prostate Cancer That is Locally Advanced or At High Risk of Relapse
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: bicalutamide|DRUG: Goserelin Acetate|DRUG: docetaxel|DRUG: Estramustine phosphate sodium|DRUG: acetylsalicylic acid|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth and Tolerance of Cow's Milk-Based Infant Formulas
Status: COMPLETED
Conditions: Growth
Interventions: OTHER: Previously marketed infant formula|OTHER: Previously marketed formula using a similar protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Trial l of Panobinostat Given in Combination With Trastuzumab and Paclitaxel in Adult Female Patients With HER2 Positive Metastatic Breast Cancer
Status: COMPLETED
Conditions: HER-2 Positive Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: IV LBH589|DRUG: Oral LBH589|DRUG: trastuzumab|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Capillary Index Score Trial
Status: COMPLETED
Conditions: Acute Stroke|Brain Ischemia|Ischemic Stroke
Interventions: PROCEDURE: Endovascular Treatment (EVT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Repetitive Transcranial Magnetic Stimulation in the Prevention of Relapse of Depression
Status: COMPLETED
Conditions: Depression
Interventions: PROCEDURE: repetitive Transcranial Magnetic Stimulation (rTMS)|BEHAVIORAL: counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Yttrium Y 90 Resin Microspheres Data Collection in Unresectable Liver Cancer: the RESIN Study
Status: COMPLETED
Conditions: Localized Non-Resectable Adult Liver Carcinoma
Interventions: OTHER: Yttrium-90 Resin Microspheres
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Single and Repeat Doses of DMT in Healthy Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke
Interventions: DRUG: N,N-Dimethyltryptamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Evaluation of HCPA-1 Silicone Stent in the Treatment of Central Airway Obstructions
Status: UNKNOWN
Conditions: Tracheobronchomalacia
Interventions: PROCEDURE: Rigid bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Effect on an Ionic Silver Dressing in Head and Neck Patients With Malignant Fungating Wound
Status: UNKNOWN
Conditions: Head and Neck Neoplasms|Head and Neck Cancer|Wounds|Ulcer
Interventions: OTHER: silver-releasing dressings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Beverages Containing Orange or Apple Pomace on Digestive Health in Adults
Status: COMPLETED
Conditions: Digestive Health
Interventions: OTHER: Orange juice + Orange Pomace|OTHER: Orange Juice|OTHER: Apple Juice and Apple Pomace|OTHER: Apple Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Epidemiology of Gallbladder Sludge and Stones in Pregnancy
Status: COMPLETED
Conditions: Cholelithiasis
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Postoperative Use of Dextenza vs a Standard Regimen After PRK
Status: NOT_YET_RECRUITING
Conditions: Steroid Ophthalmic Insert
Interventions: DRUG: Dextenza 0.4Mg Ophthalmic Insert|DRUG: Topical Fluorometholone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2a Study to Investigate REM0046127 in Mild to Moderate Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DRUG: REM0046127 High Dose|DRUG: REM0046127 Low Dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Hepatitis C Treatment in Injection Drug Users
Status: COMPLETED
Conditions: Hepatitis C|Liver Diseases|Drug Abuse|Alcoholism
Interventions: DRUG: Pegylated Interferon and Ribavirin|BEHAVIORAL: Psychosocial|BEHAVIORAL: On-site (MMT Clinic) HCV evaluation and treatment|BEHAVIORAL: Off-site HCV evaluation and treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Oxymetazoline Added on Nasal Steroid in Rhinitis With Persistent Nasal Obstruction
Status: COMPLETED
Conditions: Nasal Obstruction Present Finding
Interventions: DRUG: oxymetazoline|DRUG: Placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplant for Relapsing Clostridium Difficile Infection in Adults and Children Using a Frozen Encapsulated Inoculum
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: DRUG: Fecal Microbiota Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prostate Specific Membrane Antigen (PSMA) or (FACBC) PET/CT Site-Directed Therapy for Treatment of Prostate Cancer, Flu-BLAST-PC Study
Status: RECRUITING
Conditions: Prostate Adenocarcinoma
Interventions: PROCEDURE: Positron Emission Tomography|PROCEDURE: Lymphadenectomy|RADIATION: Radiation Therapy|DRUG: Abiraterone Acetate|DRUG: Prednisone|PROCEDURE: Computed Tomography|DRUG: Abiraterone|PROCEDURE: PSMA PET Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance and Safety of the Surgical Hemostatic Agent "HEMOCOLLAGENE®" in Patients Requiring Oral Surgery
Status: COMPLETED
Conditions: Oral Hemorrhage
Interventions: DEVICE: HEMOCOLLAGENE® : Sterile absorbable hemostatic sponges based on bovine collagen - class III MD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Open-label Study With Tocilizumab in Patients With Rheumatoid Arthritis in a Local Environment
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab [RoActemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deployment o the Multidisciplinary Prospective Cohort Imminent
Status: RECRUITING
Conditions: Chronic Inflammatory Disease|Angioedema|Severe Asthma|Lupus|Atopic Dermatitis|Psoriatic Arthritis|Multiple Sclerosis|Systemic Sclerosis|Behçet Disease
Interventions: GENETIC: Biobanking with genetic analysis|OTHER: SF-12 questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Trial of Ivermectin Plus Doxycycline for the Treatment of Confirmed Covid-19 Infection
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Ivermectin and Doxycycline|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of INFUSE Bone Graft (BMP-2) in the Treatment of Tibial Pseudarthrosis in Neurofibromatosis Type 1 (NF1)
Status: TERMINATED
Conditions: NF1|Congenital Pseudarthrosis of Tibia
Interventions: DEVICE: INFUSE Bone Graft (BMP-2)|PROCEDURE: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Transanal Irrigation for Low Anterior Resection Syndrome.
Status: RECRUITING
Conditions: Low Anterior Resection Syndrome
Interventions: DEVICE: Peristeen® Transanal irrigation system with the conic catheter|DEVICE: Standard reusable enema
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identify Bacteria Associated With Metabolic Diseases That Reside Both in Intestinal Crypts and in Blood
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: obese patients|OTHER: diabetic patients|OTHER: patients free of obesity and diabetes|OTHER: patients free type 2 diabetes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Carbetocin Nasal Spray for the Treatment of Hyperphagia in Prader-Willi Syndrome
Status: RECRUITING
Conditions: Hyperphagia in Prader-Willi Syndrome
Interventions: DRUG: Carbetocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Docetaxel for Localized Progressive Castration-resistant Prostate Cancer (CRPC)
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: DRUG: Taxotere|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-FES PET/CT in Imaging Patients With Desmoid Tumors
Status: TERMINATED
Conditions: Deep Fibromatosis/Desmoid Tumor|Familial Adenomatous Polyposis
Interventions: DRUG: F-18 16 Alpha-Fluoroestradiol|PROCEDURE: Positron Emission Tomography|PROCEDURE: Computed Tomography|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Dose-ranging Study of Pyronaridine/Artesunate in Adults Patients With Plasmodium Falciparum Malaria
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria
Interventions: DRUG: pyronaridine/artesunate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacodynamics, Pharmacokinetics, and Safety Study of Hydrochlorothiazide and Canagliflozin in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Canagliflozin 300 mg once daily and HCTZ 25 mg once daily
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Difference Between Rehabilitation With or Without Strength Training After Total Knee Replacement
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Rehabilitation with strength training|OTHER: Rehabilitation without strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sofosbuvir Plus Ribavirin in Chronic Genotype 1, 2 and 3 Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV) Co-infected Adults
Status: COMPLETED
Conditions: Hepatitis C|Human Immunodeficiency Virus
Interventions: DRUG: SOF|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HPV Vaccine Reminders - SEARCH II Study
Status: RECRUITING
Conditions: Human Papillomavirus Vaccination
Interventions: BEHAVIORAL: Text Message/automated phone reminder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: DEFLECT III: A Prospective, Randomized Evaluation of the TriGuard™ HDH Embolic Deflection Device During TAVI
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: TriGuard HDH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Two Interventions in Patients With Low Educational Level With Diabetes to Reduce Inequalities in Self-care Behavior
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: OTHER: Face-to-face|OTHER: Face-to-face intervention plus telephone reinforcement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Acupuncture on Quiescent Crohn's Disease
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Crohn Disease
Interventions: OTHER: acupuncture|OTHER: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Study of Tuberculin Purified Protein Derivative (JHP/Dose)
Status: UNKNOWN
Conditions: Tuberculosis Infection
Interventions: BIOLOGICAL: To confirm the potency of Aplisol formulated with newly produced Tuberculin PPD compared to PPD-S2 standard.|BIOLOGICAL: Reactivity of Aplisol compared to reference standard PPD-S2.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Gardasil 9 Vaccine in Preventing HPV Infection in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Allogeneic Hematopoietic Stem Cell Transplant Recipient|Hematopoietic and Lymphoid Cell Neoplasm
Interventions: BIOLOGICAL: Recombinant Human Papillomavirus Nonavalent Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Artificial Sweeteners in Breast Milk
Status: COMPLETED
Conditions: Breastfeeding|Diabetes Mellitus|Overweight
Interventions: DIETARY_SUPPLEMENT: Artificial sweeteners (acesulfame-potassium, sucralose, saccharine, cyclamate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Video and Brochure and Discharge Instructions for Childhood Fever in the Pediatric Emergency Department
Status: COMPLETED
Conditions: Fever|Child, Only
Interventions: OTHER: discharge instructions with pamphlet|OTHER: discharge instructions with video|OTHER: verbal discharge instructions only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Comparison of a DTaP-IPV-HB-PRP~T Combined Vaccine to Infanrix™-Hexa, When Administered With Prevnar® in Thai Infants
Status: COMPLETED
Conditions: Hepatitis B|Polio|Diphtheria|Pertussis|Haemophilus Influenzae Type b
Interventions: BIOLOGICAL: DTaP-IPV-HB-PRP~T and Pneumococcal polysaccharide vaccines|BIOLOGICAL: DTaP-HB-IPV and Pneumococcal polysaccharide vaccines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Canadian Observational Study in Metastatic Cancer of the Prostate: A Study of ZYTIGA Use in the Community Urology Setting
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: OTHER: Abiraterone Acetate (ZYTIGA): Prostate Cancer Registry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lifestyle Interventions for the Treatment of Non-alcoholic Fatty Liver Disease in Overweight and Obese Adults
Status: UNKNOWN
Conditions: Non-Alcoholic Fatty Liver Disease|Obesity
Interventions: BEHAVIORAL: Lifestyle education|BEHAVIORAL: Intensive lifestyle intervention|BEHAVIORAL: Hypocaloric low-carbohydrate diet plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conditioning Brain Responses to Improve Thigh Muscle Function After Anterior Cruciate Ligament Reconstruction
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Injury
Interventions: BEHAVIORAL: Operant Conditioning|BEHAVIORAL: Control|DEVICE: Single Pulse Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Education on Self-Efficacy and Adaptation to Stoma of Individuals With Stoma
Status: COMPLETED
Conditions: Stoma Ileostomy|Stoma Colostomy|Self Efficacy|Adjustment|Colorectal Cancer|Colorectal Disorders
Interventions: BEHAVIORAL: At home education via video conferencing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using Neuroplasticity-Based Computerized Training to Improve Emotion Regulation in Bipolar Disorder (BRAINS)
Status: COMPLETED
Conditions: Bipolar Disorder|Bipolar I Disorder|Bipolar Affective Disorder|Bipolar Disorder I|Bipolar Depression
Interventions: BEHAVIORAL: Cognitive Control of Emotion (CCE) Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Three Different Mouthrinses in Dental Plaque Control and Early Wound Healing
Status: COMPLETED
Conditions: Periodontitis|Wound Healing
Interventions: DRUG: Alcohol-based Chlorhexidine Gluconate 0.12%|DRUG: Alcohol-free Chlorhexidine Gluconate 0.12%|DRUG: C31G
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Development of Fecal Scoring for the Management of Fecal Impaction With Regards to Lower Urinary Tract Dysfunction
Status: COMPLETED
Conditions: Fecal Impaction|Lower Urinary Tract Disorder|Bladder Dysfunction|Bowel Dysfunction
Interventions: DRUG: Lactitol Monohydrate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy
Status: RECRUITING
Conditions: Corneal Opacity
Interventions: DRUG: OCT-guided laser phototherapeutic keratectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EVEREST: Efficacy of Vasopressin Antagonism in hEart failuRE: Outcome Study With Tolvaptan
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DRUG: Tolvaptan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Epidyolex® in Lennox Gastaut and Dravet Syndrome: an Observational Study in ITALY
Status: NOT_YET_RECRUITING
Conditions: Lennox Gastaut Syndrome|Dravet Syndrome
Interventions: DRUG: Epidiolex 100 mg/mL Oral Solution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Two Types of Biopsy in Patients With Breast Lesions
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: Needle localized breast biopsy with specimen x-ray|PROCEDURE: Low dose radioactive seed followed by surgery and mammogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Androgen Receptor, Implications for Health and Wellbeing: Natural History Study of Individuals With Androgen Insensitivity
Status: RECRUITING
Conditions: Androgen Insensitivity Syndrome|Metabolic Parameters in AIS, CAIS, PAIS and MAIS|Tumor Formation in AIS, CAIS, PAIS and MAIS|Sexual Function AIS, CAIS, PAIS and MAIS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate Safety and Tolerability of a Single Dose of PF-06741086 in Chinese Adult Participants With Severe Hemophilia
Status: COMPLETED
Conditions: Severe Hemophilia
Interventions: BIOLOGICAL: PF-06741086
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability, and Pharmacokinetics Study of Human Monoclonal Antibody BRII-196
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: BRII-196|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study for Validating the Equivalence of Bloomlife MFM-Pro to Clinical Standard-of-care for Performing Antepartum Fetal Monitoring
Status: COMPLETED
Conditions: Fetal Monitoring
Interventions: DEVICE: Bloomlife MFM-Pro
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-64565111 in Type 2 Diabetes Mellitus (T2DM)
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: JNJ-64565111|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Double Blinded Randomized Control Study of the Use of Fibrinogen in High-Risk Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Complication During Procedure
Interventions: DRUG: Fibrinogen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pyruvate in Patients With Cardiogenic Shock and Intra-aortic Balloon Counterpulsation
Status: COMPLETED
Conditions: Shock, Cardiogenic|Heart Failure|Acute Myocardial Infarction
Interventions: DRUG: Pyruvate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Analysis of Bupivacaine in the Presence and Absence of Perineural Dexamethasone in Axillary Blockade
Status: COMPLETED
Conditions: Analgesia|Acute Pain|Upper Extremity Injury
Interventions: DRUG: Bupivacaine Hydrochloride|DRUG: Bupivacaine Hydrochloride with Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: MyoGene: Effects of Acute Exercise on (Myokine) Gene Expression in Human Skeletal Muscle
Status: COMPLETED
Conditions: Exercise|Muscle|Gene Expression|Myokine
Interventions: OTHER: Single legged exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intracorporeal Versus Extracorporeal Roux-en-Y Esophagojejunostomy During Laparoscopic Total Gastrectomy for Gastric Cancer
Status: UNKNOWN
Conditions: Stomach Neoplasms|Minimally Invasive Surgery|Anastomosis
Interventions: PROCEDURE: Intracorporeal Roux-en-Y esophagojejunostomy|PROCEDURE: Extracorporeal Roux-en-Y esophagojejunostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Young Adult-Mediated Intervention to Increase Colorectal Cancer Screening
Status: WITHDRAWN
Conditions: Young Adult-Mediated Intervention to Increase Colorectal Cancer Screening
Interventions: BEHAVIORAL: Changes in CRC screening awareness and intentions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Gastric Gluten-Degradation Activity of PvP001
Status: TERMINATED
Conditions: Digestive System Disease
Interventions: DRUG: Low-dose PvP001|DRUG: Medium-dose PvP001|DRUG: High-dose PvP001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Testing the Efficacy of A Scalable, Telephone-Delivered, Guided Imagery Tobacco Cessation Intervention
Status: RECRUITING
Conditions: Smoking Cessation|Smoking|Smoking Reduction|Smoking, Cigarette|Smoking (Tobacco) Addiction|Smoking Habit
Interventions: OTHER: Guided Imagery Intervention|OTHER: Standard Behavioral Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Remote Ischemic Preconditioning on Restenosis Post Lower Limb Revascularization Angioplasty
Status: SUSPENDED
Conditions: Peripheral Vascular Diseases
Interventions: OTHER: Remote Ischemic Preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Pulsed-dye Laser Versus Timolol Topical Solution Versus Observation on the Growth of Hemangioma in Newborn
Status: RECRUITING
Conditions: Hemangioma
Interventions: DRUG: topical timolol maleate|DEVICE: Pulsed dye laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mineral Nano Pathology
Status: RECRUITING
Conditions: Arthroplasty
Interventions: PROCEDURE: hip prosthesis removed metal / polyethylene, simple mobility|PROCEDURE: hip prosthesis removed metal / polyethylene, double mobility|PROCEDURE: hip prosthesis removed ceramic/ polyethylene, simple mobility|PROCEDURE: hip prosthesis removed ceramic/ polyethylene, double mobility|PROCEDURE: Primary implanted hip prosthesis|PROCEDURE: hip prosthesis removed metal/metal|PROCEDURE: hip prosthesis removed ceramic/ceramic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Efficacy and Safety of Nebivolol in Younger Patients (18 - 54 Years)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Nebivolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of an Ultrathin Strut Biodegradable Polymer Sirolimus-Eluting Stent With a Durable Polymer Everolimus-Eluting Stent for Patients With Acute ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Coronary Artery Disease|Acute Coronary Syndrome
Interventions: DEVICE: Orsiro|DEVICE: Xience
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shoulder Prosthesis Telerehab Care Trial
Status: RECRUITING
Conditions: SHOULDER ARTHROPLASTY|REHABILITATION|TELEREHABILITATION
Interventions: DEVICE: APP|OTHER: PHYSICAL THERAPY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electrical Stimulation Effect on Coronally Advanced Flap
Status: COMPLETED
Conditions: Gingival Recession, Generalized
Interventions: PROCEDURE: CAF|DEVICE: ES|DEVICE: SHAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Pharmacokinetics of VRC01, VRC01LS, and VRC07-523LS, Potent Anti-HIV Neutralizing Monoclonal Antibodies, in HIV-1-Exposed Infants
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: VRC01|BIOLOGICAL: VRC01LS|BIOLOGICAL: VRC07-523LS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of GLP-1 and GIP on Insulin Secretion in Type-1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type-1 Diabetes Mellitus
Interventions: OTHER: glucagon like peptide -1|OTHER: NaCl|OTHER: glucose dependent insulinotropic polypeptide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: RAISE: Randomized Placebo-Controlled Idiopathic Thrombocytopenic Purpura (ITP) Study With Eltrombopag
Status: COMPLETED
Conditions: Purpura, Thrombocytopaenic, Idiopathic
Interventions: DRUG: eltrombopag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minocycline to Treat Branch Retinal Vein Occlusion
Status: COMPLETED
Conditions: Retinal Vein Occlusion
Interventions: DRUG: Minocycline|OTHER: Placebo|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Monitoring of Inflammatory Conditions
Status: COMPLETED
Conditions: Inflammatory Disease|Crohn Disease|Ulcerative Colitis|Rheumatoid Arthritis|System; Lupus Erythematosus|Psoriatic Arthritis|Reactive Arthritis|Inflammatory Arthritis|Psoriasis
Interventions: OTHER: Questionnaire|OTHER: Semi-structured interview
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects With Non-Alcoholic Steatohepatitis
Status: COMPLETED
Conditions: Non-Alcoholic Steatohepatitis
Interventions: DRUG: EDP-305 Dose 1|DRUG: EDP-305 Dose 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Low Dose ColchiciNe on the InciDence of POAF
Status: TERMINATED
Conditions: Atrial Fibrillation|Cardiac Surgery|Colchicine Adverse Reaction
Interventions: DRUG: Colchicine|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess Efficacy and Safety of RT001 in Subjects With Infantile Neuroaxonal Dystrophy
Status: ACTIVE_NOT_RECRUITING
Conditions: Infantile Neuroaxonal Dystrophy
Interventions: DRUG: RT001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Intervention With Families of Children With Special Health Care Needs
Status: WITHDRAWN
Conditions: Child Maltreatment|Children With Special Health Care Needs (CSHCN)
Interventions: BEHAVIORAL: Intervention|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: INVestIgation of rheumatiC AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies, Superiority
Status: WITHDRAWN
Conditions: Rheumatic Heart Disease
Interventions: DRUG: Rivaroxaban (15 mg)|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: tDCS and Psychotherapy for the Treatment of Anxiety Disorders
Status: UNKNOWN
Conditions: Anxiety Disorders
Interventions: DEVICE: active tDCS|DEVICE: sham tDCS|BEHAVIORAL: CBT-UP|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma
Status: RECRUITING
Conditions: Cardiovascular Disorder|Clonal Hematopoiesis|Hodgkin Lymphoma
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Electronic Health Record Review|PROCEDURE: Magnetic Resonance Imaging|OTHER: Survey Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess the Safety and Tolerability of Incremental Doses of QAB149 in Adults With Mild-to-moderate Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: QAB149
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mid-Urethral Sling Tensioning Trial
Status: COMPLETED
Conditions: Urinary Stress Incontinence
Interventions: DEVICE: Retropubic Midurethral Sling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between Body Composition and Growth Hormone, SIRT Signaling, Protein Turnover and Insulin Sensitivity
Status: COMPLETED
Conditions: Healthy
Interventions: BEHAVIORAL: 72 hour fast|BEHAVIORAL: control, 12 hour fast|DRUG: Growth hormone|DRUG: Olbetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rehabilitation of Visual Function After Brain Injury
Status: RECRUITING
Conditions: Stroke, Ischemic|Brain Injuries|Stroke Hemorrhagic|Traumatic Brain Injury
Interventions: DEVICE: Neuro Vision Technology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Efficacy Levobupivacaine 0.125% Versuss Ropivacaine 0.2% in Hemodynamic Alterations in Labor and Fetal Repercussions
Status: NOT_YET_RECRUITING
Conditions: Hemodynamic Instability|Epidural|Pregnancy|Fetal Cardiac Disorder
Interventions: DRUG: Levobupivacaine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Adding Concurrent Chemotherapy to IMRT in the Treatment of Stage II Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Effects of Chemotherapy
Interventions: DRUG: Concurrent chemotherapy with cisplatin|RADIATION: Intensity modulated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab +/- Ipilimumab in Patients With Advanced, Refractory Pulmonary or Gastroenteropancreatic Poorly Differentiated Neuroendocrine Tumors (NECs)
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Carcinoma
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kesuting Syrup in the Treatment of Corona Virus Disease 2019 (COVID-19)
Status: COMPLETED
Conditions: COVID-19 Pneumonia|Cough
Interventions: DRUG: Kesuting syrup|DRUG: LianHuaQingWen Granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Modified Circular and Natural Tooth Brushing Methods in Effectiveness of Dental Plaque Removal
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Natural Tooth Brushing Method|OTHER: Modified Circular Tooth Brushing Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacodynamic and Pharmacokinetic Study of RO5508887 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Placebo|DRUG: RO5508887
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Hematopoietic Stem Cell Dysfunction in the Elderly After Severe Injury
Status: RECRUITING
Conditions: Trauma Injury
Interventions: OTHER: Bone marrow collection|OTHER: Blood collection|OTHER: Clinical data collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of LY2599666 in Healthy Participants and Participants With Mild Cognitive Impairment or Alzheimer's Disease (AD)
Status: TERMINATED
Conditions: Healthy|Alzheimer's Disease|Mild Cognitive Impairment
Interventions: DRUG: LY2599666|DRUG: Solanezumab|DRUG: Placebo SC|DRUG: Placebo IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Impact of Venetoclax on the Quality of Life for Subjects With Relapsed (Your Cancer Has Come Back) or Refractory (no Response to Previous Cancer Treatments) Chronic Lymphocytic Leukemia (CLL) While Receiving Venetoclax Monotherapy (a Single Agent).
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia (CLL)
Interventions: DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atacicept Demonstrating Dose RESponSe
Status: WITHDRAWN
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Placebo|DRUG: Atacicept|DRUG: Atacicept|DRUG: Atacicept|DRUG: Atacicept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Mental Training and Internal Attentional Control
Status: UNKNOWN
Conditions: Attention Impaired|Mental Health Issue|Rumination
Interventions: BEHAVIORAL: Attention Feedback Awareness and Control Training (A-FACT)|BEHAVIORAL: Mindful Disengagement from Thoughts Training (MDTT)|BEHAVIORAL: Placebo-Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of SR-hGH (Sustained-release Human Growth Hormone, Declage Inj.)
Status: COMPLETED
Conditions: Growth Hormone Deficiency
Interventions: DRUG: sustained-release recombinant human GH (SR-rhGH)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole Exome Sequencing and Whole Genome Sequencing for Nonimmune Fetal/Neonatal Hydrops
Status: RECRUITING
Conditions: Nonimmune Fetal Hydrops|Nonimmune Hydrops in Neonate|Genetic Disorders
Interventions: DIAGNOSTIC_TEST: Whole Exome Sequencing|DIAGNOSTIC_TEST: Whole Genome Sequencing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Emotion Detectives In-Out: Feasibility and Efficacy of a Blended Version of the Unified Protocol for Children
Status: NOT_YET_RECRUITING
Conditions: Anxiety Disorders
Interventions: BEHAVIORAL: Emotion Detectives In-Out|BEHAVIORAL: Coping Cat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT