pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy
Status: RECRUITING
Conditions: Nephrotic Syndrome|Proteinuria|Autoimmune Disease|Glomerular Disease|Membranous Glomerulonephritis
Interventions: DRUG: Rituximab Infusion|DRUG: Oral Cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Evaluation of Vital Pulpotomy Techniques in Primary Molars Using of Premixed Bioactive Bioceramic MTA (Neo-putty) as a Novel Pulpotomy Medication Versus Formocresol
Status: NOT_YET_RECRUITING
Conditions: Vital|Pulpotomy|Techniques
Interventions: DRUG: A cotton pellet moistened with full-strength FC|DRUG: Neo-Putty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Optimize the Therapeutic Pathway of Peginterferon Treatment in Patients With CHB Based on IFNA2p.Ala120Thr /ISGs.
Status: RECRUITING
Conditions: Hepatitis B
Interventions: DRUG: Nucleotide Analog|DRUG: Interferon Alfa-2A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anesthetics to Prevent Lung Injury in Cardiac Surgery
Status: COMPLETED
Conditions: Inflammatory Lung Injury|Ischemia-Reperfusion Lung Injury|Postoperative Pulmonary Complications
Interventions: DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The IDEAL-PCI Extended Registry
Status: WITHDRAWN
Conditions: Coronary Arterioscleroses|Platelet Dysfunction Due to Drugs
Interventions: DRUG: DAPT reduction|DRUG: DAPT on-target|DRUG: DAPT intensification
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Effect of Severe Renal Impairment on Gilteritinib Compared to Healthy Participants With Normal Renal Function
Status: COMPLETED
Conditions: Renal Impaired|Gilteritinib|Normal Renal Function|Pharmacokinetics of ASP2215
Interventions: DRUG: Gilteritinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of LAM-002A for the Prevention of Progression of COVID-19
Status: COMPLETED
Conditions: COVID-19 Disease
Interventions: DRUG: Apilimod Dimesylate Capsule|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Efficacy of Atezolizumab in Combination With Obinutuzumab Plus Lenalidomide in Patients With Relapsed or Refractory Follicular Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Follicular
Interventions: DRUG: Atezolizumab (MPDL3280A) [TECENTRIQ]|DRUG: Lenalidomide|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention to Improve Adherence in Teen Kidney Transplant
Status: COMPLETED
Conditions: Kidney Transplantation|Medication Adherence
Interventions: BEHAVIORAL: Action-focused problem-solving|DEVICE: Electronic pillbox monitoring, dose reminders, and feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Quality of Life and Gut Health in Pediatric Patients With Cystic Fibrosis
Status: RECRUITING
Conditions: Cystic Fibrosis in Children
Interventions: DIETARY_SUPPLEMENT: Multistrain Probiotic|DIETARY_SUPPLEMENT: Placebo - maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Exploring the Use of Transdermal Methylphenidate to Reduce Fall Risk in Patients With Dementia.
Status: TERMINATED
Conditions: Dementia|Accidental Falls|Apathy
Interventions: DRUG: Transdermal Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Quality of Life and Supportive Care Preferences Following Radiation Therapy in Prostate Cancer Survivors
Status: COMPLETED
Conditions: Prostate Carcinoma
Interventions: OTHER: Undergo HRV and wear accelerometer to assess therapy complications|PROCEDURE: Dual X-ray Absorptiometry|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MultiStem Administration for COVID-19 Induced ARDS (MACoVIA)
Status: UNKNOWN
Conditions: ARDS
Interventions: BIOLOGICAL: MultiStem|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Loss and Transfusion Requirement in Infants Treated With Tranexamic Acid
Status: SUSPENDED
Conditions: Craniosynostoses
Interventions: DRUG: Tranexamic Acid|DRUG: Tranexamic Acid|DRUG: Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Antibiotics on the Incidence of Biliary Tract Infections After PTCD for Malignant Obstructive Jaundice
Status: UNKNOWN
Conditions: The Influence of Antibiotics on the Incidence of Biliary Tract Infections After PTCD for Malignant Obstructive Jaundice
Interventions: OTHER: antibiotic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multicenter, Single-Arm, Open-Label Expanded Access Program for Lenalidomide Plus Dexamethasone in Previously Treated Subjects With Multiple Myeloma
Status: COMPLETED
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Chemotherapy Sequenced by or Combined With EGFR-TKIs for NSCLC Patients Failed to EGFR-TKIs Therapy
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: combined group|DRUG: Sequenced group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Testing Response Effect of KY1005 Against Moderate-to-Severe Atopic Dermatitis, The STREAM-AD Study
Status: COMPLETED
Conditions: Eczema|Atopic Dermatitis
Interventions: DRUG: KY1005|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fiber-rich Foods to Treat Obesity and Prevent Colon Cancer
Status: RECRUITING
Conditions: Colon Cancer|Obesity
Interventions: DIETARY_SUPPLEMENT: High Fiber Diet Featuring Legumes (HLD)|DIETARY_SUPPLEMENT: Healthy American Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Homeless Veterans and Peer Whole Health Coaching
Status: RECRUITING
Conditions: Acute Care Service Utilization|Mental Health Status|Physical Health Status|Housing
Interventions: BEHAVIORAL: Peer Support-Whole Health Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiosurgery for Patients With Hepatic Metastases.
Status: COMPLETED
Conditions: Metastatic Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: RADIATION: stereotactic radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: OSTEOPATHY IN THE TREATMENT OF IBS SYMPTOMS IN ADULTS
Status: NOT_YET_RECRUITING
Conditions: OSTEOPATHY IN THE TREATMENT OF IBS SYMPTOMS IN ADULTS
Interventions: OTHER: the active osteopathic treatment (AOT)|OTHER: the sham osteopathic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the French Maternal and Child Protection Services From 11 French Territories That Have Received Common Intervention Guidelines
Status: COMPLETED
Conditions: Parent-Child Relations|Maltreatment by Parent|Parents|Mental Health Wellness 1
Interventions: OTHER: PANJO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas
Status: NOT_YET_RECRUITING
Conditions: High Grade Glioma|Glioma|Glioma, Malignant|Neoplasms, Neuroepithelial|Neuroectodermal Tumors|Photosensitizing Agents|Neoplasm Malignant|Brain Neoplasms, Adult, Malignant|Central Nervous System Neoplasms|Brain Tumor|Tumour, Residual
Interventions: DRUG: 5-Aminolevulinic Acid (5-ALA) Gliolan®|PROCEDURE: Fluorescence-Guided Surgery using 5-aminolevulinic acid (5-ALA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tolvaptan Open-label Pilot Efficacy, Tolerability, and Safety Study in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Status: COMPLETED
Conditions: Polycystic Kidney, Autosomal Dominant
Interventions: DRUG: Tolvaptan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dry Needling Multifidus on Thickness of Transversus Abdominis in Healthy Individuals
Status: COMPLETED
Conditions: Back Pain
Interventions: PROCEDURE: Dry needling|PROCEDURE: Sham needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rasburicase and Allopurinol in Treating Patients With Hematologic Malignancies
Status: TERMINATED
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Blastic Phase Chronic Myelogenous Leukemia|Contiguous Stage II Adult Burkitt Lymphoma|de Novo Myelodysplastic Syndromes|Noncontiguous Stage II Adult Burkitt Lymphoma|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Adult Burkitt Lymphoma|Stage I Adult Burkitt Lymphoma|Stage III Adult Burkitt Lymphoma|Stage IV Adult Burkitt Lymphoma|Untreated Adult Acute Lymphoblastic Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: rasburicase|DRUG: allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Injection of Erythropoietin on Visual Functions in Patients With Late Onset Optic Neuropathy
Status: COMPLETED
Conditions: Optic Neuropathy
Interventions: DRUG: erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preliminary Study on the Metastatic Rate and Clinical Significance of the Anterior Leaf of Vesicouterine Ligament in Early Stage Cervical Cancer
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: PROCEDURE: Type B resection or type C resection of the anterior leaf of vesicouterine ligament during the radical hysterectomy (type C)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Ultrasound-guided Serratus Plane Block During Video-assisted Thoracoscopic Lobectomy
Status: UNKNOWN
Conditions: Anesthesia, Conduction|Pain Management
Interventions: PROCEDURE: Serratus plane block|PROCEDURE: General anesthesia only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous CD117+ Progenitor Cell Mobilization for Lung Transplantation
Status: COMPLETED
Conditions: COPD|Cystic Fibrosis|Pulmonary Fibrosis
Interventions: DRUG: Plerixafor mobilization of autologous CD117 stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RBD-HPV: Risk-Based De-Intensification for HPV+ HNSCC
Status: WITHDRAWN
Conditions: Human Papillomavirus (HPV)|Head and Neck Squamous Cell Carcinoma (HNSCC)
Interventions: RADIATION: RT 50 Gy|RADIATION: RT 54 GY|RADIATION: RT 60 GY|OTHER: Induction Therapy|DRUG: Carboplatin|DRUG: Cisplatin 200|DRUG: Cisplatin 240
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Positron Emission Tomography (PET) Imaging Agent [18F]-ODS2004436 as a Marker of EGFR Mutation in Subjects With NSCLC
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: OTHER: Injection of [18F]-ODS2004436 radiotracer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Locally ablatIVe thErapy for oLigo-progressive gastrOintestiNal maliGnancies (LIVELONG)
Status: RECRUITING
Conditions: Esophageal Cancer|Small Bowel Cancer|Gastroesophageal-junction Cancer|Gastric Cancer|Colorectal Cancer|Appendiceal Cancer|Biliary Cancer|Gall Bladder Cancer|Intrahepatic Cholangiocarcinoma|Extrahepatic Cholangiocarcinoma|Oligoprogressive
Interventions: DEVICE: Ablative local therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Effectiveness, Immunogenicity and Safety of Meningococcal ABCWY Vaccine Administered to Healthy Adolescents
Status: COMPLETED
Conditions: Meningococcal Disease
Interventions: BIOLOGICAL: Meningococcal ABCWY|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study on Effects of BMS-955176 on the Pharmacokinetics of Probe Substrates
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: CYP and transporter probe substrates|DRUG: BMS-955176|DRUG: BMS-955176 plus CYP and transporter probe substrates
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pranayama Breathing and Uncontrolled Hypertension
Status: COMPLETED
Conditions: Uncontrolled Hypertension
Interventions: BEHAVIORAL: Class instruction of breathing exercises|BEHAVIORAL: DVD instruction of breathing exercises|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Networks of Bacterium-Metabolite Interactions in the Small Intestine
Status: RECRUITING
Conditions: Diet, Healthy|Microbial Colonization
Interventions: OTHER: Test meal (high fat = Nutricia Calogen®, or high carbohydrate = Nutricia preOp®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cardiac Hemodynamics in Overlap Syndrome (COPD With Obstructive Sleep Apnea)
Status: WITHDRAWN
Conditions: Chronic Obstructive Airway Disease
Interventions: DEVICE: Bi-level positive airway pressure (BPAP)|DRUG: Oxygen|DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Exercise Cardiovascular Responses Following Energy Drink Consumption
Status: COMPLETED
Conditions: QTc Interval
Interventions: DIETARY_SUPPLEMENT: Energy Drink|DIETARY_SUPPLEMENT: Placebo-control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Subthalamic Nucleus (STN) Stimulation and Obsessive-Compulsive Disorder (OCD)
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: PROCEDURE: deep brain stimulation|PROCEDURE: No stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemoglobin, Neutrophil to Lymphocyte Ratio and Platelet Count Improve Prognosis Prediction in Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Neoplasms|Blood Cell Count|Neoplasm Staging|Prognosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Studying Changes in Physical Function Measures in Stem Cell Transplant Patients at Risk for Steroid Myopathy
Status: TERMINATED
Conditions: Acute Graft Versus Host Disease
Interventions: BEHAVIORAL: Exercise Intervention|OTHER: Physical Performance Testing|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Study of Melatonin in Stroke Patients
Status: UNKNOWN
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Melatonin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pregabalin in Preventing Acute Pain Syndrome in Patients Receiving Paclitaxel
Status: COMPLETED
Conditions: Pain|Peripheral Neuropathy
Interventions: DRUG: pregabalin|DRUG: placebo|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intratumoral and Systemic Hiltonol® (Poly-ICLC) in Prostate Cancer Patients on Active Surveillance
Status: RECRUITING
Conditions: Prostate Cancer Patients on Active Surveillance
Interventions: DRUG: Poly-ICLC intramuscular (IM) injection|DRUG: Poly-ICLC, Intertumoral (IT) injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MG-K10 in Subjects With Atopic Dermatitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: MG-K10|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Novel Sound Changing Principles in Hearing Instruments to Determine Their Application - 2018_12
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Hearing Aid without NR|DEVICE: Hearing Aid with NR_A|DEVICE: Hearing Aid with NR_B|DEVICE: Hearing Aid with NR_C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Antihypertensive Response to Losartan and Genetic Polymorphisms
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: losartan potassium|DRUG: Comparator: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjustment of Antibiotic Dosage in Pediatric Oncology Patients With Febrile Neutropenia and Augmented Renal Clearance
Status: RECRUITING
Conditions: Febrile Neutropenia
Interventions: DRUG: Dosage Adjustment Rules for Augmented Renal Clearance (DAR-ARC) for piperacillin-tazobactam and meropenem|DRUG: Standard dosages of piperacillin-tazobactam or meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantitative Evaluation of the Effect of Dehydration and Rehydration Levels on Tooth Color
Status: ENROLLING_BY_INVITATION
Conditions: Tooth Discoloration
Interventions: DIAGNOSTIC_TEST: Mobile Dental Photography|DIAGNOSTIC_TEST: Mobile Dental Photography with cross-polarization filter|DIAGNOSTIC_TEST: Mobile Dental Photography with gray reference card|DIAGNOSTIC_TEST: Mobile Dental Photography with cross-polarization filter and gray reference card|DIAGNOSTIC_TEST: Digital Camera|DIAGNOSTIC_TEST: Digital Camera with cross-polarization filter|DIAGNOSTIC_TEST: Digital Camera with cross-polarization filter and gray reference card|DIAGNOSTIC_TEST: Digital Camera with gray reference card|DIAGNOSTIC_TEST: Rayplicker|DIAGNOSTIC_TEST: Rayplicker with gray reference card|DIAGNOSTIC_TEST: Vita Easyshade|DIAGNOSTIC_TEST: Vita Easyshade with gray reference card
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Evaluation of the Use of Surgical Tube Technique Versus Hyaluronic AcidInjection in Reconstruction of the Interproximal Papilla
Status: UNKNOWN
Conditions: the Clinical Effect of Surgical Tube Technique in Reconstruction of the Interproximal Papilla
Interventions: PROCEDURE: Tube technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of a Topical Scalp Treatment for Dry Scalp Conditions in Children and Adult
Status: UNKNOWN
Conditions: Dermatitis, Seborrheic|Dry Skin; Eczema
Interventions: DRUG: Natural Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acupuncture on the Treatment of Endovenous Ablation on Pain, IL17 and IL 23
Status: COMPLETED
Conditions: Pain|Interleukin|Vessels; Varicose
Interventions: OTHER: Group A ( Group Acupuncture)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Outreach Core Activities
Status: RECRUITING
Conditions: Cancer Education|Spanish Language Cancer Education
Interventions: BEHAVIORAL: Cancer CientoUno (101) program|BEHAVIORAL: Latinos y el cáncer/Hablemos de cáncer (Translation in English: Latinos and Cancer/Let's Talk About Cancer)|BEHAVIORAL: ¡Salud! Serie de Charlas (Translation in English: Health! Talk Series)|BEHAVIORAL: Community/Researcher Forum: El Puente (Translation in English: The Bridge).|BEHAVIORAL: Lunch and Learn Updated Recommendations Series.|BEHAVIORAL: Community Engagement (CE) Training Program for U54 Partnership Investigators|BEHAVIORAL: Community Advisory Panels (CAP)|BEHAVIORAL: Research Corner|BEHAVIORAL: Community-based Training Program (CBTP) for Community Leaders and Stakeholders.|BEHAVIORAL: Integrate Cancer 101 into the Stakeholders Programs|BEHAVIORAL: Community Engagement (CE) Training Program for Lay Community Members
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intranasal Dexmedetomidine in Children Undergoing Adenotonsillectomy Suffering From Mild Upper Respiratory Tract Infection
Status: RECRUITING
Conditions: Dexmedetomidine|Adenotonsillectomy|Respiratory Tract Infections
Interventions: DRUG: Dexmedetomidine group|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Catheter Ablation Versus Anti-arrhythmic Drugs for Ventricular Tachycardia
Status: RECRUITING
Conditions: Heart Disease Structural Disorder|Ventricular Tachycardia|Cardiomyopathy, Dilated|Sarcoidosis|Cardiomyopathy, Hypertrophic|Cardiomyopathy Ischemic|Cardiomyopathy, Familial|Arrhythmogenic Right Ventricular Cardiomyopathy 1|Arrhythmogenic Left Ventricular Cardiomyopathy
Interventions: PROCEDURE: Ablation|DRUG: Anti-arrhythmic Drugs (AADs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Motor Learning After Upper Limb Peripheral Nerve Injury
Status: COMPLETED
Conditions: Peripheral Nerve Injury at Forearm Level (Diagnosis)
Interventions: OTHER: conventional physical therapy|OTHER: mirror therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label, Long-term Study Evaluating Safety and Efficacy of Subcutaneous Amlitelimab in Participants Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis
Status: RECRUITING
Conditions: Dermatitis Atopic
Interventions: DRUG: Amlitelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Computerized Opioid Overdose Prevention Program
Status: COMPLETED
Conditions: Computer + Fluency|Computer Only|Treatment as Usual
Interventions: BEHAVIORAL: Computer + Fluency|BEHAVIORAL: Computer Only|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Speed of Glucose Absorption
Status: RECRUITING
Conditions: Healthy|Nutrition, Healthy
Interventions: DIETARY_SUPPLEMENT: 45 grams Voom Pocket Rocket Electro Energy|DIETARY_SUPPLEMENT: 45 grams SIS Go Isotonic Energy Gel|DIETARY_SUPPLEMENT: 45 grams Maurten Gel 160
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy & Safety Study of Nasalfent (Fentanyl Citrate Nasal Spray) for Treatment of Breakthrough Cancer Pain in Patients Taking Regular Opioids
Status: COMPLETED
Conditions: Cancer Pain
Interventions: DRUG: Fentanyl (Nasalfent, Fentanyl Citrate Nasal Spray)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness Study of Ketoconazole and Betamethasone to Treat Fungal Infection and Dermatophytosis
Status: COMPLETED
Conditions: Tinea
Interventions: DRUG: Candicort®|DRUG: Nizoral®|DRUG: Baycuten N®|DRUG: Canesten®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: rTMS-tACS Stimulation on Improving Cognitive Function in Bipolar Disorder
Status: RECRUITING
Conditions: Bipolar Disorder in Remission
Interventions: DEVICE: Repetitive Transcranial magnetic stimulation and transcranial alternating current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Family-Centered Cesarean Delivery
Status: COMPLETED
Conditions: Patient Satisfaction|Earlier Family Bond Initiation|Maternal and Neonatal Outcomes
Interventions: PROCEDURE: Family-Centered Cesarean|PROCEDURE: Traditional Cesarean
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Group Antenatal/Postnatal Care in Rwanda
Status: COMPLETED
Conditions: Pregnancy Complications|Preterm Birth|Preterm Labor|Stillbirth|Low Birth Weight|Neonatal Mortality
Interventions: BEHAVIORAL: Group ANC/PNC|PROCEDURE: Ultrasound+Pregnancy Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telephone Support in Advanced Gastrointestinal Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastrointestinal Neoplasm Malignant|Caregiver Burden
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy|BEHAVIORAL: Education/Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of JMT101 Combined With Osimertinib in Patients With Non-Small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced or Metastatic Non-Small Cell Lung Cancer|EGFR Exon20 Insertion Mutations
Interventions: DRUG: JMT101|DRUG: Osimertinib Mesylate Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Treatment of Neuroendocrine Cervix Carcinomar With Camrelizumab Combined With Etoposide and Cisplatin
Status: RECRUITING
Conditions: Carcinoma|Cervix Carcinoma
Interventions: DRUG: Karelizumab combined with etoposide and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preanesthetic Analgesia/Nociception Index (ANI) and Propofol Injection Pain
Status: COMPLETED
Conditions: Pain, Acute|Analgesia|Nociceptive Pain
Interventions: DEVICE: Analgesia/Nociception Index (ANI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: OTO-104 for the Treatment of Meniere's Disease
Status: COMPLETED
Conditions: Meniere's Disease
Interventions: DRUG: OTO-104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subretinal Macugen® for Neovascular Age-Related Macular Degeneration
Status: UNKNOWN
Conditions: Age-related Macular Degeneration
Interventions: DRUG: Pegaptanib (Macugen®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetic Study of MB12066 in Healthy Volunteers
Status: COMPLETED
Conditions: Metabolic Syndrome|Obesity
Interventions: DRUG: MB12066|DRUG: MB12066|DRUG: MB12066|DRUG: MB12066|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: The Effect of Sujok Therapy on Patient Comfort, Pain Intensity, and Anxiety Level in Cancer Patients With Port Catheter Placement
Status: NOT_YET_RECRUITING
Conditions: Cancer|Chemotherapy Effect
Interventions: BEHAVIORAL: Su Jok
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Resiliency Training for Adolescent Neurofibromatosis Patients Via Videoconferencing With Skype
Status: COMPLETED
Conditions: Neurofibromatoses
Interventions: BEHAVIORAL: Stress Management Group 1|BEHAVIORAL: Stress Management Group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: StAT-TB (Statin Adjunctive Therapy for TB): A Phase 2b Dose-finding Study of Pravastatin in Adults With Tuberculosis
Status: COMPLETED
Conditions: Tuberculosis|Pulmonary Tuberculosis
Interventions: DRUG: Pravastatin|DRUG: Rifafour|DIETARY_SUPPLEMENT: Vitamin B6
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Text Messages to Improve Antiretroviral Treatment (ART) Adherence in HIV+ Methamphetamine Users
Status: COMPLETED
Conditions: HIV|AIDS
Interventions: BEHAVIORAL: individualized Texting for Adherence Building (iTAB)|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intermittent Automated Devices for Labor Analgesia in Emilia Romagna
Status: TERMINATED
Conditions: Labor Pain
Interventions: DEVICE: Programmed Intermittent bolus|OTHER: Manual epidural bolus|DRUG: Levobupivacaine|DRUG: Sufentanil 4 mcg|DRUG: Sufentanil 5 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Gastric Bypass vs LAP-BAND for Treatment of Morbid Obesity
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: PROCEDURE: Gastric bypass surgery|PROCEDURE: Lap-Band
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Effects of Desflurane and TIVA on Antioxidant System in Morbidly Obese Patients
Status: COMPLETED
Conditions: Oxidative Stress|Morbid Obesity
Interventions: DIAGNOSTIC_TEST: Total Antioxidant Status|DIAGNOSTIC_TEST: Total Oxidant Status|DEVICE: Bispectral Index|OTHER: Invasive arterial monitorization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Lumbar Disc Prosthesis Versus Multidisciplinary Rehabilitation; 8-year Follow-up
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: PROCEDURE: Lumbar total disc replacement|BEHAVIORAL: Multidisciplinary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Acceptability of Long-Acting Cabotegravir (CAB LA) for the Prevention of HIV Among Adolescent Males - A Sub-study of HPTN 083
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Cabotegravir (CAB) tablet|DRUG: CAB LA|DRUG: Tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Effects of Mechanical Traction and Manual Traction on Cervicogenic Headache
Status: UNKNOWN
Conditions: Cervicogenic Headache
Interventions: DEVICE: mechanical traction group|OTHER: manuel traction group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy (SBRT) for Invasive Breast Cancer Patients Not Undergoing Definitive Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: Stereotactic Body Radiation Therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of t-DCS and Cognitive Training on Apathy in Elderly With Minor Neurocognitive Impairment
Status: ENROLLING_BY_INVITATION
Conditions: Apathy|Neurocognitive Disorders
Interventions: OTHER: SHAM tDCS|OTHER: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Autologous MSCs Combined to Biomaterials to Enhance Bone Healing
Status: COMPLETED
Conditions: Delayed Union After Fracture of Humerus, Tibial or Femur
Interventions: PROCEDURE: Implantation of bone substitute plus autologous cultured mesenchymal cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fludeoxyglucose F 18 PET/CT Scans in Predicting Therapy Response in Patients With Stage IIIA Non-Small Cell Lung Cancer Undergoing Chemoradiation
Status: WITHDRAWN
Conditions: Stage IIIA Non-small Cell Lung Cancer
Interventions: PROCEDURE: positron emission tomography/computed tomography (PET/CT)|RADIATION: fludeoxyglucose F 18
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ferumoxytol-Enhanced MRI in Imaging Lymph Nodes in Patients With Locally Advanced Rectal Cancer
Status: TERMINATED
Conditions: Locally Advanced Rectal Carcinoma|Stage III Rectal Cancer AJCC v7|Stage IIIA Rectal Cancer AJCC v7|Stage IIIB Rectal Cancer AJCC v7|Stage IIIC Rectal Cancer AJCC v7
Interventions: PROCEDURE: Contrast-enhanced Magnetic Resonance Imaging|DRUG: Ferumoxytol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Characterisation of Biofilm Growth on Coated vs. Uncoated Urinary Catheter Surfaces in Normal Clinical Use
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DEVICE: M4D|DEVICE: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of TEAS on the Incidence Rate of SIRS in Patients Undergoing Abdominal Surgery
Status: COMPLETED
Conditions: Systemic Inflammatory Response Syndrome|Inflammation
Interventions: DEVICE: TEAS|DEVICE: Sham TEAS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: SCH 39304 as Therapy for Acute Cryptococcal Meningitis in HIV-Infected Patients Followed by Maintenance Therapy
Status: COMPLETED
Conditions: Meningitis, Cryptococcal|HIV Infections
Interventions: DRUG: SCH 39304
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ofatumumab in Treatment of Pemphigus Vulgaris
Status: TERMINATED
Conditions: Pemphigus Vulgaris
Interventions: BIOLOGICAL: Ofatumumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of Peri Operative CHemotherapy In Patients With CINSARC High-risk Localized Soft Tissue Sarcoma
Status: RECRUITING
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Standard of care + chemotherapy|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aspirin for Prevention of Preeclampsia
Status: UNKNOWN
Conditions: Preeclampsia
Interventions: DRUG: aspirin 162 mg|DRUG: aspirin 81 mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Symptoms Control and adhErenCe Assessment During Treatment With MepolizUmab New pREfilled Devices
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: Pre-filled syringe, mepolizumab 100 mg/month|DRUG: Auto-injector pen, mepolizumab 100 mg/month
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: vHDU Phase 5: Impact of an Ambulatory Monitoring System on Deterioration Detection and Clinical Outcomes
Status: RECRUITING
Conditions: Surgery|Deterioration, Clinical
Interventions: DEVICE: Ambulatory monitoring system|DEVICE: Active alerting system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dose Response of Intravenous Sincalide(CCK-8) for Gallbladder Emptying
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Experimental Sequence ABC|DRUG: Experimental Sequence ACB|DRUG: Experimental Sequence BAC|DRUG: Experimental Sequence BCA|DRUG: Experimental Sequence CAB|DRUG: Experimental Sequence CBA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Comparison of TULSA Procedure vs. Radical Prostatectomy in Participants With Localized Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Prostate Adenocarcinoma
Interventions: DEVICE: Radical Prostatectomy|DEVICE: TULSA Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet-rich Plasma Versus Corticosteroid Injection for the Treatment of Femoroacetabular Impingement
Status: TERMINATED
Conditions: Femoroacetabular Impingement
Interventions: DRUG: platelet-rich plasma injection|DRUG: Kenalog 10 MG/ML Injectable Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Role of Flavanols In Cardiovascular Function in Healthy Aging
Status: COMPLETED
Conditions: Aging
Interventions: DIETARY_SUPPLEMENT: High Flavanol first then Low Flavanol|DIETARY_SUPPLEMENT: Low Flavanol first then High Flavanol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treat-and-extend Regimen of Aflibercept in Diabetic Macular Edema (VIBIM Study)
Status: UNKNOWN
Conditions: Macular Edema, Diabetic
Interventions: DRUG: aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pomalidomide in Combination With Low-dose Dexamethasone or Pomalidomide in Combination With Low-dose Dexamethasone and Daratumumab in Subjects With Relapsed or Refractory Multiple Myeloma Following Lenalidomide-based Therapy in the First or Second Line Setting
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Pomalidomide|DRUG: Dexamethasone|DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of the Fatty Acid Amide Hydrolase Inhibitor Palmitoylethanolamide in Bipolar Depression
Status: RECRUITING
Conditions: Bipolar Depression
Interventions: DRUG: Palmitoylethanolamide (PEA)|DRUG: Placebo|DRUG: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glucarpidase After High-Dose Methotrexate in Patients With Osteosarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteosarcoma
Interventions: DRUG: Glucarpidase|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety of Combining Two Radionuclide Therapies to Treat Mid-gut Neuroendocrine Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Tumor, Malignant|Neuroendocrine Tumor Gastrointestinal, Hormone-Secreting
Interventions: DRUG: 90Y-DOTA-3-Tyr-Octreotide|DRUG: 131I-MIBG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acids in Preventing Joint Symptoms in Patients With Stage I-III Breast Cancer Receiving Anastrozole, Exemestane, or Letrozole
Status: COMPLETED
Conditions: Recurrent Breast Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: DIETARY_SUPPLEMENT: omega-3 fatty acid supplement|OTHER: Placebo|OTHER: Clinical assessments|OTHER: Assessment of therapy complications|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Correlative/special studies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study to Evaluate Efficacy and Safety of ALLO-ASC-DFU in Patients With Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: BIOLOGICAL: ALLO-ASC-DFU|OTHER: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Hemostatic Powder Versus Clinical Management for the Treatment of Upper Gastrointestinal Bleeding From Tumor Lesions
Status: TERMINATED
Conditions: Gastrointestinal Hemorrhage|Gastrointestinal Neoplasms
Interventions: DEVICE: Hemospray (Endoscopic treatment with hemostatic powder)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Chronic Lymphocytic Leukemia|Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Hematopoietic and Lymphoid Cell Neoplasm|Hodgkin Lymphoma|Lymphoblastic Lymphoma|Myelodysplastic Syndrome|Myelofibrosis|Myeloproliferative Neoplasm|Non-Hodgkin Lymphoma
Interventions: DRUG: Letermovir|BIOLOGICAL: Multi-peptide CMV-Modified Vaccinia Ankara Vaccine|OTHER: Placebo Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of On-eye Optical Performances of the RMY-100 Lens
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: etafilcon A|DEVICE: Habitual Orthokeratology Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study to Evaluate the Acid-Inhibitory Effect of Multiple Oral Doses of Vonoprazan (TAK-438)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Vonoprazan|DRUG: Esomeprazole|DRUG: Rabeprazole sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel/Carboplatin + Galunisertib for Patients With Carcinosarcoma of the Uterus or Ovary
Status: COMPLETED
Conditions: Carcinosarcoma, Ovarian
Interventions: DRUG: Galunisertib|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT