pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Corticosteroids Therapy and Pneumocystis Jirovecii Pneumonia (PCP)
Status: WITHDRAWN
Conditions: Pneumocystis Carinii Pneumonia
Interventions: DRUG: Antibiotics only|DRUG: Antibiotics + Corticosteroids|DRUG: Corticosteroids + antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iodine I 131 Monoclonal Antibody TNT-1/B in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: RADIATION: iodine I 131 monoclonal antibody TNT-1/B
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: External Nitric Oxide Measurement Through SNO Degradation
Status: ENROLLING_BY_INVITATION
Conditions: Healthy|Unconscious
Interventions: DEVICE: Alonefire SV003 10W 365nm UV Flashlight
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial Investigating Safety, Tolerability, PK and PD for Multiple Doses of NNC9204-0530 in Male and Female Subjects Being Overweight or With Obesity
Status: COMPLETED
Conditions: Metabolism and Nutrition Disorder|Obesity
Interventions: DRUG: NNC9204-0530|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Abiraterone Acetate Plus Prednisone in Patients With Metastatic Castration-Resistant Prostate Cancer Who Have Failed Docetaxel-Based Chemotherapy
Status: COMPLETED
Conditions: Prostate Neoplasms
Interventions: DRUG: Abiraterone acetate|DRUG: Placebo|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prolonged Popliteal Fossa Nerve Blockade (Prolonged Pop)
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Dexamethasone|DRUG: Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of BAY 43-9006 in Combination With Bicalutamide in Patients With Chemo-Naïve Hormone Refractory Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate
Interventions: DRUG: BAY 43-9006
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Two Different Repeat Doses of GSK2190915 on the QTc Interval.
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: GSK2190915 100mg|DRUG: GSK2190915 200mg|DRUG: moxifloxacin 400mg|DRUG: moxifloxacin placebo|DRUG: GSK2190915 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation of Patients With Lung Chronic Obstructive Pulmonary Disease
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: upper limb exercises|OTHER: without training for upper limb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Collagen Paste vs Mucosal Advancement Flap for FIA
Status: RECRUITING
Conditions: Fistula-in-ano
Interventions: PROCEDURE: Collagen Paste|PROCEDURE: Mucosal advancement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Diaphragmatic Breathing Exercise on Fatigue and Quality of Life in Pregnant Women With Gestational Diabetes
Status: NOT_YET_RECRUITING
Conditions: Gestational Diabetes Mellitus in Pregnancy|Pregnancy in Diabetic|Fatigue|Quality of Life
Interventions: BEHAVIORAL: Experimental Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Determine and Evaluate a Safe and Tolerated Dose of HDM201 in Patients With Selected Advanced Tumors That Are TP53wt
Status: COMPLETED
Conditions: Advanced Solid and Hematological TP53wt Tumors
Interventions: DRUG: HDM201|DRUG: ancillary treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Untreated Childhood Medulloblastoma
Interventions: DRUG: Cisplatin|RADIATION: Craniospinal Irradiation|DRUG: Cyclophosphamide|RADIATION: Involved-Field Radiation Therapy|OTHER: Laboratory Biomarker Analysis|DRUG: Lomustine|OTHER: Quality-of-Life Assessment|RADIATION: Radiation Therapy|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daratumumab After Stem Cell Transplant in Treating Patients With Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Plasma Cell Myeloma|Secondary Amyloidosis
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|BIOLOGICAL: Daratumumab|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Trial of Naproxen Sodium and Diphenhydramine Hydrochloride Soft Capsules Versus Naproxen Sodium and Diphenhydramine Hydrochloride Tablets in Healthy Adult Subjects Under Fed Conditions
Status: COMPLETED
Conditions: Clinical Pharmacology
Interventions: DRUG: Naproxen sodium and diphenhydramine hydrochloride soft capsules|DRUG: Naproxen sodium and diphenhydramine hydrochloride coated tablets (Aleve PM, BAY98-7111)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer That Can Not Be Surgically Removed
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Donor Lymphocyte Infusion With Azacitidine to Prevent Hematologic Malignancy Relapse After Stem Cell Transplantation
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Acute Lymphoid Leukemia|Juvenile Myelomonocytic Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: azacitidine|BIOLOGICAL: donor lymphocyte infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Dosimetry of Lutathera in Adolescent Patients With GEP-NETs and PPGLs
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastroenteropancreatic Neuroendocrine Tumors|Pheochromocytoma|Paraganglioma
Interventions: DRUG: Lutetium [177Lu] oxodotreotide/dotatate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Synagis (Palivizumab) Immunoprophylaxis in Preterm Infants With High Risk of Severe Respiratory Syncytial Virus (RSV) Infection
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infection
Interventions: BIOLOGICAL: Synagis (palivizumab), monoclonal antibody for passive immunoprophylaxis against severe RSV disease administered according to usual clinical practice.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dexmedetomidine Versus General Anesthesia on the Diagnosis of Endobronchial US-Guided Transbronchial Needle Aspiration
Status: COMPLETED
Conditions: Sedation|Dexmedetomidine|EBUS Guided Transbronchial Needle Aspiration
Interventions: PROCEDURE: dexmedetomidine|PROCEDURE: general anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid in Percutaneous Nephrolithotomy
Status: COMPLETED
Conditions: Percutaneous Nephrolithotomy|Intraoperative Use of Tranexamic Acid
Interventions: DRUG: Tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Non-contrast Magnetic Resonance Angiography in Deep Inferior Epigastric Perforator Flap Breast Reconstruction Planning
Status: RECRUITING
Conditions: Breast Cancer|Postsurgical Acquired Absence of Organ
Interventions: OTHER: Non-contrast MRA in preoperative perforator vessels mapping for deep inferior epigastric perforator (DIEP) flap breast reconstruction planning.|OTHER: CTA with iodine contrast in preoperative perforator vessels mapping for deep inferior epigastric perforator (DIEP) flap breast reconstruction planning.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: 2nd-line Therapy With Nal-IRI After Gem/Nab-pac in Advanced Pancreatic Cancer - Predictive Role of 1st-line Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Pancreatic Cancer|Metastatic Pancreatic Cancer
Interventions: DRUG: Irinotecan Liposomal Injection [Onivyde]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK and ECG Determinations Following 8 Weeks of HyBryte Treatment for Cutaneous T-Cell Lymphoma
Status: COMPLETED
Conditions: Cutaneous T-Cell Lymphoma/Mycosis Fungoides
Interventions: DRUG: Hypericin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Changes in Bowel Movement Frequency Following the Consumption of PHGG in Adults With Constipation
Status: COMPLETED
Conditions: Constipation - Functional
Interventions: DIETARY_SUPPLEMENT: PHGG|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Thalidomide Reduces Arteriovenous Malformation Related Gastrointestinal Bleeding
Status: COMPLETED
Conditions: Arteriovenous Malformation|Hereditary Hemorrhagic Telangiectasia|Hematochezia|Melena
Interventions: DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: M6®-C Artificial Cervical Disc Two-Level IDE Pivotal Study
Status: RECRUITING
Conditions: Cervical Disc Degenerative Disorder
Interventions: DEVICE: M6-C Artificial Cervical Disc|DEVICE: ACDF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risperidone Versus Olanzapine for Mania in Preschool Children 4 to 6 Years of Age With Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder|Mania
Interventions: DRUG: risperidone (Risperdal)|DRUG: olanzapine (Zyprexa)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: GEnetic Testing in Elective Single Embryo Transfer (GETSET): A Randomized Clinical Trial
Status: RECRUITING
Conditions: Infertility, Female
Interventions: OTHER: Preimplantation genetic testing for aneuploidy (PGTA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Earpiece for Transcutaneous Auricular Neurostimulation (tAN) for Symptoms of Opioid Withdrawal
Status: COMPLETED
Conditions: Opioid-use Disorder|Opioid Withdrawal
Interventions: DEVICE: Sparrow Therapy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Intracoronary Hyperoxemic Oxygen Therapy in Anterior Acute Myocardial Infarction Patients (IC-HOT)
Status: COMPLETED
Conditions: Anterior Wall Acute Myocardial Infarction
Interventions: DEVICE: SSO2 Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD7 CAR-T Bridging to alloHSCT for R/R CD7+Malignant Hematologic Diseases
Status: RECRUITING
Conditions: Hematologic Diseases|Neoplasms
Interventions: DRUG: CD7 CAR-T cells injection|OTHER: Allogeneic hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EUS-Coeliac Plexus Block Versus Radiofrequency Ablation in Pain Relief of Patients With Malignancy
Status: UNKNOWN
Conditions: Cancer of Pancreas|Pancreatic Neoplasms|Pain|Cancer-Associated Pain|Pain Management
Interventions: DRUG: 98% dehydrated alcohol|DEVICE: 19G EUSRA needle, Taewoong Medical, Korea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Volanesorsen on Cardiac Repolarization Conducted in Healthy Volunteers
Status: COMPLETED
Conditions: Abnormalities, Cardiovascular
Interventions: DRUG: Volanesorsen|DRUG: Moxifloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of SOX Regimen Combined With Camrelizumab as Neoadjuvant Treatment in Locally Advanced Gastric Cancer: a Phase II, Single-arm Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Stomach Neoplasms|Digestive System Neoplasms|Neoplasms|Digestive System Diseases|Stomach Diseases|Neoplasms by Site
Interventions: DRUG: Camrelizumab|DRUG: SOX|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: N-803 Combined With the Broadly Neutralizing Antibodies Plus or Minus haNK Cells for HIV
Status: WITHDRAWN
Conditions: Hiv|HIV/AIDS|HIV Infections|AIDS|AIDS and Infections|Aids/Hiv Problem
Interventions: BIOLOGICAL: N-803 and bNAbs|BIOLOGICAL: haNK™ Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Demonstrate the Efficacy and Safety of Cenestin 0.3 mg for the Treatment of Hot Flashes
Status: COMPLETED
Conditions: Hot Flashes
Interventions: DRUG: Cenestin 0.3 mg Tablets|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: B-Cell Depleting Therapy (Rituximab) as a Treatment for Fatigue in Primary Biliary Cirrhosis
Status: COMPLETED
Conditions: Fatigue|Primary Biliary Cirrhosis
Interventions: BIOLOGICAL: Rituximab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AMNIOEXCEL® Plus vs A Marketed Comparator vs SOC in the Management of Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: OTHER: AMNIOEXCEL Plus Amniotic Membrane|DEVICE: A Marketed Comparator|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endogenous Renin-Angiotensin-Aldosterone System and Glucose Metabolism
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: OTHER: Low Salt diet plus Placebo tablet|OTHER: Low Sodium diet plus Salt tablet|DRUG: Epleronone|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chronic Transcranial Direct Current Stimulation in Patients With Systemic Autoimmune Myopathies
Status: RECRUITING
Conditions: Myopathy
Interventions: OTHER: Chronic transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Impact of Smoking Information on Concerns About Radon
Status: COMPLETED
Conditions: Lung Neoplasms|Radon Exposure|Smoking|Intention|Risk Reduction Behavior
Interventions: BEHAVIORAL: Radon & Smoking Synergistic|BEHAVIORAL: Radon Only|BEHAVIORAL: Radon and Smoking Isolated|BEHAVIORAL: EPA|BEHAVIORAL: Idaho
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Impact of Pre-Operative Web-based Breast Cancer Information on the Quality of Patient Decision-Making
Status: COMPLETED
Conditions: Breast Cancer|Knowledge, Attitudes, Practice
Interventions: OTHER: Web-based decision aid|OTHER: Standard websites
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Manual Therapy Plus Therapeutic Exercise in Geriatrics
Status: NOT_YET_RECRUITING
Conditions: Pain|Disability Physical|Aging Disorder
Interventions: OTHER: Manual Therapy|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stress Biomarkers Leading to Professional Burnout Among People Involved in a Mobile Intensive Care Unit During the COVID-19 Pandemic
Status: COMPLETED
Conditions: Occupational Stress
Interventions: BEHAVIORAL: Assessment of work-related stress|BIOLOGICAL: Saliva sample collection|OTHER: Cardiac and electrodermal recordings|BEHAVIORAL: Assessment of behavioral response to emotional stimulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Comparing Clindamycin Phosphate and Benzoyl Peroxide Gel to Acanya® Gel and Both to a Vehicle Control in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Clindamycin Phosphate and Benzoyl Peroxide Gel, 1.2%/2.5%|DRUG: Acanya® Gel, 1.2%/2.5%|DRUG: Vehicle of test product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Serplulimab Combined With Nab-paclitaxel and Cisplatin in Neoadjuvant Therapy for Resectable Esophageal Squamous Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Serplulimab Combined With Nab-paclitaxel and Cisplatin|DRUG: nab-paclitaxel，Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of Pioglitazone After Co-administration With Different Doses of BI 10773 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pioglitazone|DRUG: Pioglitazone - low dose|DRUG: BI 10773 - low dose|DRUG: BI 10773 - medium dose|DRUG: BI 10773 - high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three Different Cross-linking Protocols for Treatment of Pediatric Keratoconus
Status: COMPLETED
Conditions: Corneal Ectasia
Interventions: PROCEDURE: Standard CXL|PROCEDURE: Accelerated CXL|PROCEDURE: Transepithelial CXL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telemedicine Enabling Patients in Self-care Behaviors
Status: COMPLETED
Conditions: Arrythmia
Interventions: OTHER: Standard of care group|BEHAVIORAL: Telemedicine group|BEHAVIORAL: Telemedicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study Comparing Appearance and Function of Three Different Dental Implant Designs When Placed in Front Region of Upper Jaw
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially
Interventions: DEVICE: OsseoSpeed™|DEVICE: NobelSpeedy™ Replace®|DEVICE: NanoTite™ Certain® PREVAIL®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow Aspirate Concentrate (BMAC) for Treatment of Critical Limb Ischemia (CLI)
Status: COMPLETED
Conditions: Critical Limb Ischemia
Interventions: DEVICE: BMAC injection|DEVICE: Placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of 3D Printing High-fidelity Craniofacial Manikin to Teach Noninvasive Positive Pressure Ventilation
Status: NOT_YET_RECRUITING
Conditions: Satisfaction, Personal
Interventions: OTHER: 3D-printed high-fidelity craniofacial manikin model education|OTHER: Traditional model education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mirtazapine for the Treatment of Methamphetamine Dependence Among MSM (M2.0)
Status: COMPLETED
Conditions: Amphetamine-Related Disorders
Interventions: DRUG: Mirtazapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Detection of Circulating Tumor Cells (CTCs) in Patients With Liver Cancer Undergoing Cryosurgery Combined With DC-CIK Treatment
Status: COMPLETED
Conditions: Neoplastic Cells, Circulating
Interventions: OTHER: Flow cytometry (FCM)|OTHER: RT-PCR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quetiapine Augmentation for Primary Anxiety Disorder or Mood Disorders With Co-morbid Anxiety Symptoms
Status: COMPLETED
Conditions: Primary Anxiety Disorders|Mood Disorders With Comorbid Anxiety Symptoms
Interventions: DRUG: Quetiapine extended release tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-CT Fusion System for Interventional Radiology Procedures
Status: UNKNOWN
Conditions: CT Guided Biopsy|CT Guided Drain Placement Within the Abdomen or Pelvis|CT Guided Injection of Muscle or Nerve Within the Pelvis
Interventions: DEVICE: Ultrasound-CT Fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Localized Neuropathic Pain: Topical Treatment Versus Systemic Treatment
Status: TERMINATED
Conditions: Neuropathic Pain
Interventions: DRUG: Lidocaine patch 5%|DRUG: Capsaicin 8% Patch|DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of 2 Surgical Skin Preparation Methods in Reducing Surgical Wound Drainage After Total Hip or Knee Replacement
Status: COMPLETED
Conditions: Drainage
Interventions: DRUG: Duraprep Surgical Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sjögren and Gynecologic Considerations
Status: COMPLETED
Conditions: Primary Sjögren Syndrome|Vaginitis Candida|Vaginitis|Sexual Dysfunction
Interventions: OTHER: Visual analogue scale (VAS) for dyspareunia|OTHER: Visual analogue scale (VAS) for vaginal dryness|OTHER: The European League Against Rheumatism Sjögren's Syndrome Disease Activity Index (ESSDAI)|OTHER: The European League Against Rheumatism Sjögren's Syndrome Patient Reported Index (ESSPRI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Above-Knee-High Application of Lower Limb Compression and Its Impact on Clinical Outcome in Patients Hospitalized With Heart Failure Exacerbation.
Status: RECRUITING
Conditions: Heart Failure; With Decompensation|Lower Extremity Edema|Heart Failure，Congestive
Interventions: OTHER: Application of compression to bilateral lower extremities of patients using appropriately-sized elastic compression stockings.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Boceprevir/Peginterferon/Ribavirin for Chronic Hepatitis C: Erythropoietin Use Versus Ribavirin Dose Reduction for Anemia (P06086 AM2)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Boceprevir|DRUG: Peginterferon alfa-2b (PEG2b)|DRUG: Ribavirin (RBV)|DRUG: Erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Analgesic and Anti-Inflammatory Impact of Photobiomodulation in Patients With Dental Implants
Status: COMPLETED
Conditions: Dental Pain and Sensation Disorder
Interventions: DEVICE: laser therapy After implant surgery, laser therapy (LLLT) was applied|DEVICE: SHAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Elafin in Healthy Subjects
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Elafin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Xingnaojing for Mild-to-severe Acute Ischemic Stroke
Status: UNKNOWN
Conditions: Acute Ischemic Stroke|Stroke, Acute|Stroke, Ischemic
Interventions: DRUG: Xingnaojing injection|DRUG: Xingnaojing placebo injection|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The SUSTAIN Study Compares the Effects of Sustained and Immediate-release Pramipexole on the noctUrnal Symptoms of paTients With Advanced ParkInsoN's Disease Who Also Take L-Dopa
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Pramipexole SR|DRUG: Pramipexole IR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pregabalin Plus Lofexidine for the Outpatient Treatment of Opioid Withdrawal
Status: RECRUITING
Conditions: Opiate Withdrawal Syndrome|Opioid Use
Interventions: DRUG: LFX/PGB|DRUG: LFX/PLA-PGB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Imaging in Complications of Sinusitis
Status: NOT_YET_RECRUITING
Conditions: Rhinosinusitis|Intracranial Extension|Rhinosinusitis Chronic|Rhinosinusitis Acute|Fungal Sinusitis|Allergic Fungal Rhinosinusitis|Invasive Fungal Sinusitis (Diagnosis)
Interventions: RADIATION: Multislice CT scan of the paranasal sinuses.|RADIATION: MRI examination of the paranasal sinuses
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Obesity on Proton Pump Inhibitors
Status: RECRUITING
Conditions: Pediatric Obesity|NAFLD|GERD
Interventions: DRUG: Pantoprazole|DRUG: Midazolam injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incidence of Hepatic Hemangiomatosis in Patients With Cutaneous Hemangiomas
Status: COMPLETED
Conditions: Hemangioma
Interventions: PROCEDURE: abdominal ultrasound|OTHER: Dermatologic Examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: S0030: Capecitabine in Treating Older Patients W/Metastatic or Recurrent Colorectal Cancer That Cannot Be Surgically Removed
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of NK Cells From Sibship to Treat the Recurrence of HCC After Liver Transplantation
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: Low Dose NK cells ×4 times|BIOLOGICAL: Normal Dose NK cells ×4 times|BIOLOGICAL: Normal Dose NK cells ×8 times
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A PoC Study to Evaluate Treatments' Efficacy by Monitoring MRD Using ctDNA in HR-positive/HER2-negative EBC Population
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Giredestrant|DRUG: Abemaciclib|DRUG: Inavolisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of EPA on Prostate Cancer Cells Proliferation and Quality of Life
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: EPA|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)
Status: COMPLETED
Conditions: Chronic Low Back Pain|Hip Ostearthritis|Myofascial Pain Syndrome|Fibromyalgia|Depression|Maladaptive Coping|Lumbar Spinal Stenosis|Insomnia|Sacroiliac Joint Pain|Lateral Hip and Thigh Pain|Anxiety|Dementia|Recent Leg Length Discrepancy
Interventions: OTHER: Patient-Centered Care|OTHER: Imaging-Directed Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety And Efficacy Study Of Topic Mucopolysaccharide Polysulfate Cream In The Superficial Varicose Veins Treatment
Status: WITHDRAWN
Conditions: VARICOSE VEINS
Interventions: DRUG: TOPIC MUCOPOLYSACCHARIDE POLYSULFATE CREAM 5MG/G
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Letrozole for Frozen Embryo Transfer (FET) in Patients With Polycystic Ovary Syndrome (PCOS)
Status: WITHDRAWN
Conditions: Infertility, Female|Polycystic Ovary Syndrome|IVF|Ovulation Disorder
Interventions: DRUG: Letrozole|DRUG: estradiol valerate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics (PK) and Safety Study of XARTEMIS® XR in Postsurgical Adolescent Subjects With Moderate to Severe Acute Pain
Status: TERMINATED
Conditions: Acute Pain
Interventions: DRUG: XARTEMIS XR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of QLS31905 Combination Chemotherapy as First-Line Treatment in Patients With Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: QLS31905|DRUG: Nab paclitaxel|DRUG: Gemcitabine|DRUG: Oxaliplatin|DRUG: Capecitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Electrotherapies for Chronic Low Back Pain
Status: COMPLETED
Conditions: Non-specific Chronic Low Back Pain
Interventions: DEVICE: H-Wave|DEVICE: Transcutaneous Electrical Nerve Stimulation (TENS)|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intensity-Modulated Radiation Therapy in Treating Patients With Localized Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: RADIATION: conventional radiotherapy 74 Gy delivered in 37 fractions|RADIATION: hypofractionated radiation therapy 60 Gy in 20 fractions|RADIATION: hypofractionated radiation therapy 57 Gy in 19 fractions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Waiting for Stapler Firing in Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Staple Misfire
Interventions: PROCEDURE: standby while firing staple
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Dose Escalation and Expansion Study of [177Lu]Lu-SN201 in Participants With Advanced Cancer
Status: RECRUITING
Conditions: Solid Tumor|Metastatic Cancer|Unresectable Solid Tumor|Recurrent Solid Tumor|Locally Advanced Solid Tumor|Refractory Cancer
Interventions: DRUG: [177Lu]Lu-SN201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tadalafil in Treating Patients Undergoing Surgery for Cancer of the Oral Cavity or Oropharynx
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Tadalafil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Eszopiclone Co-Administered With Escitalopram for Insomnia in Elderly Adults With Major Depressive Disorder
Status: COMPLETED
Conditions: Insomnia
Interventions: DRUG: Eszopiclone|DRUG: Placebo|DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Injection Study Evaluating Safety and Efficacy of Ampion in Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: BIOLOGICAL: 4 mL injection of Ampion|DRUG: 4 mL Injection of Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Different Exercises on Tissue Mechanics, Strength and Neuropathy Symptoms in Type 2 Diabetes Patients
Status: RECRUITING
Conditions: Diabetic Foot|Peripheral Neuropathy With Type 2 Diabetes
Interventions: OTHER: Routine Medical Treatment|OTHER: Aerobic Exercise|OTHER: Aerobic Exercise+ Foot-Related Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ocular Lubricant Eyedrops on Lid Parallel Conjunctival Folds and Other Signs and Symptoms of Dry Eye
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: Lubricating eyedrops containing hydroxypropyl-guar
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radicle Relief 1: A Study of Health and Wellness Products on Pain and Other Health Outcomes
Status: COMPLETED
Conditions: Pain|Nociceptive Pain|Neuropathic Pain
Interventions: DIETARY_SUPPLEMENT: Relief Study Product Usage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of 2LALERG (Homeopathic Drug) in Allergic Rhinitis Related to Grass Pollen
Status: COMPLETED
Conditions: Seasonal Allergy
Interventions: DRUG: 2LALERG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Whole Body Vibration and Resistance Exercise on Carotis Intima Media and Muscle Architecture in Hypertension
Status: ENROLLING_BY_INVITATION
Conditions: Hypertension|Whole Body Vibration|Muscle Architecture|Carotid Intima Media Thickness
Interventions: OTHER: Whole body vibration and strengthening exercise|OTHER: Whole body vibration exercise|OTHER: Strengthening exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phone Call Follow-up After Crisis Centre Presentation With Suicidal Ideation and Behaviours.
Status: UNKNOWN
Conditions: Suicide|Suicidal Ideation|Suicide, Attempted|Suicide Gesture|Suicide and Self-harm
Interventions: BEHAVIORAL: Follow-up phone call
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Sequential Administration of AGN-151586 and OnabotulinumtoxinA (BOTOX) Injections in Adult Participants for Treatment of Glabellar Lines
Status: COMPLETED
Conditions: Glabellar Lines
Interventions: DRUG: AGN-151586|DRUG: BOTOX|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ventilatory Response After Non Invasive Ventilation in Type 1 Myotonic Dystrophy
Status: UNKNOWN
Conditions: Myotonic Dystrophy 1|Steinert Disease
Interventions: DEVICE: Non Invasive Ventilation.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter, Randomized, Double-Blind, Double-Dummy, Parallel-Group Comparison of the Remission Rates of Once Daily Treatment With Esomeprazole 20mg and Lansoprazole 15mg for 6 Months in Patients Whose EE Has Been Healed
Status: COMPLETED
Conditions: Erosive Esophagitis
Interventions: DRUG: Esomeprazole|DRUG: Lansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Aligners Versus Rapid Maxillary Expansion
Status: COMPLETED
Conditions: Maxillary Transverse Deficiency (MTD)
Interventions: DEVICE: Invisalign® First Phase I treatment (Align Technology, Inc., Santa Clara, CA, USA)|DEVICE: Tooth-borne Hyrax-type maxillary expander
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: China Tongxinluo Study for Myocardial Protection in Patients With Acute Myocardial Infarction
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Tongxinluo|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of Cystine Versus Nicotine Replacement Therapy
Status: RECRUITING
Conditions: Nicotine Addiction
Interventions: DRUG: Cytisine|DRUG: Nicotine Replacement Therapy (NRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Filtered Eyewear to Prevent Light-induced Melatonin Suppression - Aim 1
Status: RECRUITING
Conditions: Sleep Quality
Interventions: DEVICE: Filtered Eyewear|DEVICE: Unfiltered Eyewear|OTHER: No Filters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Icotinib Hydrochloride Cream in Patients With Mild to Moderate Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: 0.5% Icotinib hydrochloride cream|DRUG: 1.0% Icotinib hydrochloride cream|DRUG: 2.0% Icotinib hydrochloride cream|DRUG: 4.0% Icotinib hydrochloride cream|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Losartan and Simvastatin in Hypertensive Obeses With Liver Steatosis
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: Losartan + Simvastatin|DRUG: Amlodipine + Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Efficacy of a Sequential Regimen Consisting of Three Cycles of Fludarabine Followed by Tositumomab and Iodine I 131 Tositumomab
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: BIOLOGICAL: Tositumomab and Iodine I 131 Tositumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Coated Orthodontic Miniscrews With Chlorhexidine Hexametaphosphate Antimicrobial Nanoparticles
Status: COMPLETED
Conditions: Orthodontic Appliance Complication
Interventions: COMBINATION_PRODUCT: Coated Orthodontic Miniscrews with Chlorhexidine Hexametaphosphate Nanoparticles|COMBINATION_PRODUCT: Uncoated Miniscrew with Chlorhexidine Hexametaphosphate Nanoparticles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Endostatin and Chemotherapy for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: docetaxel and epirubicin|DRUG: docetaxel and epirubicin plus endostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Versus Intramuscular Administration of Methylergonovine for Uterine Contraction in Cesarean Sections
Status: WITHDRAWN
Conditions: Uterine Atony|Uterine Tone Disorders|Postpartum Hemorrhage
Interventions: DRUG: Methylergonovine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fasting ENHANCE Pilot Study
Status: RECRUITING
Conditions: Overweight and Obesity|Time Restricted Feeding|Alzheimer Disease
Interventions: BEHAVIORAL: Time Restricted Eating intervention|BEHAVIORAL: Successful Aging Comparison Group (LEARN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase II Study to Evaluate the Efficacy and Safety of Two Doses of LTX-109 in Impetigo
Status: COMPLETED
Conditions: Non-bullous Impetigo
Interventions: DRUG: LTX-109 1 %|DRUG: LTX-109 2 %|DRUG: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy and 1-MT in Treating Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Male Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: adenovirus-p53 transduced dendritic cell (DC) vaccine|DRUG: 1-methyl-d-tryptophan|OTHER: Laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Impact of Maintaining Hemoglobin Levels in Anemic Patients With Carcinoma of the Cervix
Status: SUSPENDED
Conditions: Cervical Cancer|Anemia
Interventions: PROCEDURE: Blood transfusion|PROCEDURE: Blood transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PRevention of COVID-19 With Oral Vitamin D Supplemental Therapy in Essential healthCare Teams
Status: TERMINATED
Conditions: COVID-19
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of MNTX on CYP450 2D6 in Metabolizers of Dextromethorphan
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DRUG: SC Methylnaltrexone (MNTX)|DRUG: IV Methylnaltrexone (MNTX)|DRUG: Oral Paroxetine|DRUG: SC Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Michigan Men's Diabetes Project 3 (MenD 3): Mind and Motion
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2|Depressive Symptoms|Depression
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Exercise|BEHAVIORAL: Group Discussions - Ongoing Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: SPD503 (Guanfacine Hydrochloride) in ADHD Plus Oppositional Symptoms
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: SPD503 (Guanfacine hydrochloride)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of Dayspring Active Wearable Compression Technology for Treating Lower Extremity Lymphedema
Status: COMPLETED
Conditions: Lymphedema|Lymphedema Lower Extremity|Chronic Venous Insufficiency|Secondary Lymphedema
Interventions: DEVICE: Dayspring Active Wearable Compression System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT