pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of New or Worsening Lens Opacifications in Men With Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss
Status: COMPLETED
Conditions: Cancer|Cataract|Low Bone Mineral Density|Osteopenia|Osteoporosis|Prostate Cancer
Interventions: BIOLOGICAL: Denosumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Personalized Preventive Support for Cognitive Impairment in Non-Metastatic Breast Cancer (EFACog)
Status: RECRUITING
Conditions: No Metastatic Breast Cancer
Interventions: OTHER: Face to face and telephonic interviews
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Physical-Psychological Integrative Intervention on SCI Patient: a Pilot Randomized Controlled Trial
Status: COMPLETED
Conditions: Spinal Cord Injuries|Physical Inactivity|Depression|Chronic Pain
Interventions: BEHAVIORAL: Physical-Psychological Integrative Intervention|DEVICE: Brief online didactic education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation, Treatment of Childhood Drug-Resistant Lennox-Gastaut Syndrome, A Pilot Study
Status: COMPLETED
Conditions: Lennox-Gastaut Syndrome
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Exenatide on Oral Contraceptive Pharmacokinetics in Healthy Females
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ethinyl estradiol and levonorgestrel; exenatide|DRUG: ethinyl estradiol and levonorgestrel; exenatide|DRUG: ethinyl estradiol and levonorgestrel; exenatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroinflammation in Hypertension Study
Status: RECRUITING
Conditions: Resistant Hypertension
Interventions: DRUG: Minocycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence, Phenotypes, Predictors and Prognostic Implication of Obstructive Sleep Apnea in Pulmonary Hypertension
Status: RECRUITING
Conditions: Sleep Apnea|Obstructive Sleep Apnea|Pulmonary Hypertension|Epidemiology|Predictor|Prognosis|Outcomes|Mortality
Interventions: DIAGNOSTIC_TEST: Level III portable sleep study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HFNC Alone or Associated With NIV for Immunocompromised Patients Admitted to ICU for Acute Respiratory Failure
Status: COMPLETED
Conditions: Acute Respiratory Failure|Immunosuppression
Interventions: DEVICE: NIV/HFNC|DEVICE: HFNC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Subgingival Open Sandwich Restorations
Status: COMPLETED
Conditions: Dental Restoration Failure of Marginal Integrity
Interventions: OTHER: Proximal box elevation using one of the tested materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Apabetalone for Pulmonary Arterial Hypertension
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Apabetalone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Maintenance Obinutuzumab in Treating Patients With Central Nervous System Lymphoma Who Have Achieved a Complete or Partial Response
Status: RECRUITING
Conditions: Primary Central Nervous System Lymphoma
Interventions: PROCEDURE: Cognitive Assessment|BIOLOGICAL: Obinutuzumab|OTHER: Quality of Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SERETIDE 100/50 bd (Twice Daily) Versus FLIXOTIDE 100 bd As Initial Maintenance Therapy In Moderate Asthma In Adults
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Salmeterol xinafoate/fluticasone propionate combination|DRUG: Fluticasone propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Trial of MLN2704 in Subjects With Metastatic Androgen Independent Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: MLN2704 (DM1 conjugated monoclonal antibody MLN591)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short and Long Term Effect of Early Infant Feeding and Nutritional Status on the Children's Health
Status: UNKNOWN
Conditions: Health Behavior
Interventions: DIETARY_SUPPLEMENT: Infant Formula|DIETARY_SUPPLEMENT: breast milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: R-2cda and Prolongation of Therapy With Rituximab Alone in Chronic Lymphocytic Leukaemia and Small Lymphocytic Lymphoma
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukaemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Rituximab|DRUG: Cladribine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of the Synbiotic Ecologic 825/scFOS on Intestinal Barrier Function and Immune Modulation
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Ecologic 825/scFOS|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Chemoimmunotherapy for Resectable Non-Metastatic Proficient Mismatch Repair (PMMR) Colon Cancer
Status: NOT_YET_RECRUITING
Conditions: Stage I Colon Cancer|Stage II Colon Cancer|Stage III Colon Cancer
Interventions: DRUG: Tecentriq 1200 MG in 20 ML Injection + Capecitabine 1000 mg/m2 + Oxaliplatin 130 mg/m2|DRUG: Oxaliplatin injection 85mg/m2 + Leucovorin 400mg/m2 + 5-Fluorouracil 2400mg/m2|DRUG: Oxaliplatin 130mg/m2 + Capecitabine 1000mg/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Patient Handling Study of Mometasone Furoate/Formortoral Fumarate (MF/F) Metered Dose Inhaler (MDI) With an Integrated Dose Counter in Adolescent and Adult Subjects With Asthma or Chronic Obstructive Pulmonary Disease (Study P04703AM1)
Status: COMPLETED
Conditions: Asthma|COPD
Interventions: DRUG: SCH No. 418131 (Mometasone Furoate/Formoterol Furoate abbreviated MF/F )
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Propranolol Improve Retinopathy of Prematurity Outcomes in Very Preterm Infants
Status: UNKNOWN
Conditions: Retinopathy of Prematurity
Interventions: DRUG: Propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lactoferrin in Heart Failure Patients
Status: NOT_YET_RECRUITING
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: DRUG: oral Iron|DRUG: Lactoferrin|DRUG: lactoferrin and oral iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab and Stereotactic Body Radiation Therapy (SBRT) in Advanced Solid Tumors
Status: COMPLETED
Conditions: Liver Cancer|Lung Cancer
Interventions: DRUG: Ipilimumab|RADIATION: Stereotactic Body Radiation Therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of an Oral Supplement on the Total Energy and Protein Intake of Head and Neck Cancer Patients in the Last 2 Weeks of Radiation Therapy
Status: WITHDRAWN
Conditions: Head and Neck Cancer
Interventions: DIETARY_SUPPLEMENT: Nutritional Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IMT for Primary Clostridium Difficile Infection
Status: TERMINATED
Conditions: Clostridium Difficile Infection
Interventions: BIOLOGICAL: Intestinal microbiota therapy|DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRP Treatment of Osteoarthritic Knee With a New Autologous Blood Product (CytoRich)
Status: UNKNOWN
Conditions: Osteoarthritis of the Knee
Interventions: DEVICE: Cytorich PRP kit|DEVICE: PRP kit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DEMOJUAN- DEMOnstration Area for Primary Prevention of Type 2 Diabetes, JUAN Mina and Barranquilla, Colombia
Status: COMPLETED
Conditions: Type 2 Diabetes|Glucose Metabolism Disorders
Interventions: BEHAVIORAL: Lifestyle intervention (nutrition)|BEHAVIORAL: Lifestyle intervention (physical activity)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Impact of SARS-CoV-2 Rapid Antigen Testing Kit Screening in Bangkok Community
Status: COMPLETED
Conditions: Covid19|SARS-CoV-2|Community Transmissions|Coronavirus Infections
Interventions: DIAGNOSTIC_TEST: Rapid antigen testing kit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Thyroid Function Tests and Status of Thyroid Autoantibodies in Covid-19 Patients
Status: COMPLETED
Conditions: COVID-19 Infection|Thyroid Function Tests|Inflammation; Thyroid|Inflammatory Markers
Interventions: DIAGNOSTIC_TEST: Venous blood was collected for biochemistry testing.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Fecal Microbiota Transplantation in Peripheral Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: Fecal microbiota transplantation (FMT)|OTHER: Drug: Placebo (saline)|DRUG: Methotrexate (MTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of LYC-30937-EC in Subjects With Active Ulcerative Colitis
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: DRUG: LYC-30937-EC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Amniotic Mesenchymal Stem Cell Therapy for Lupus Nephritis
Status: COMPLETED
Conditions: Lupus Nephritis|Mesenchymal Stem Cells
Interventions: DRUG: human amniotic mesenchymal stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Two Digital Therapeutics for the Prevention of Episodic Migraine
Status: COMPLETED
Conditions: Migraine|Episodic Migraine|Headache|Headache, Migraine
Interventions: DEVICE: ReMMi-D Digital Therapeutic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Formulated Eggshell Derived Nano-hydroxyapatite Containing Toothpaste With and Without Addition of Fluoride vs. Conventional Desensitizing Fluoride Containing Toothpaste in Management of Dentin Hypersensitivity
Status: NOT_YET_RECRUITING
Conditions: Dentin Hypersensitivity|Fluoride|Nano-hydroxy Apatite
Interventions: DRUG: Eggshell derived Nano-hydroxyapatite (n-HAp) with a Fluoride containing toothpaste|DRUG: Eggshell derived Nano-hydroxyapatite (n-HAp) without a Fluoride containing toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide, Dexamethasone, and Elotuzumab With or Without Cyclophosphamide in Treating Patients With Relapsed Primary Amyloidosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Primary Amyloidosis
Interventions: DRUG: Cyclophosphamide|DRUG: Dexamethasone|BIOLOGICAL: Elotuzumab|OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CANDLE - A Study of Acute Health Effects of Exposure to Particles Generated by Candles
Status: COMPLETED
Conditions: Inflammatory Response|Symptoms and Signs
Interventions: OTHER: Candle C|OTHER: Candle 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Laparoscopic Surgery or Robotic-Assisted Laparoscopic Surgery in Treating Patients With Rectal Cancer That Can Be Removed By Surgery
Status: WITHDRAWN
Conditions: Recurrent Rectal Cancer|Stage I Rectal Cancer|Stage II Rectal Cancer|Stage III Rectal Cancer
Interventions: PROCEDURE: conventional laparoscopic surgery|PROCEDURE: robotic-assisted laparoscopic surgery|PROCEDURE: quality-of-life assessment|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Depakote Extended Release (ER) Versus Seroquel for Agitated Behaviors in Nursing Home Care Unit Patients With Dementia
Status: TERMINATED
Conditions: Agitation|Dementia
Interventions: DRUG: Depakote ER|DRUG: Seroquel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
Status: RECRUITING
Conditions: Atrial Fibrillation (AF)
Interventions: BIOLOGICAL: Abelacimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration
Status: RECRUITING
Conditions: Solid Tumors
Interventions: DRUG: ORIC-114|DRUG: Chemotherapy drug
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation of the Superior Cluneal Nerve
Status: COMPLETED
Conditions: Nerve Entrapment Syndrome|Radiofrequency Ablation|Low Back Pain
Interventions: PROCEDURE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).
Status: RECRUITING
Conditions: Opioid Use Disorder
Interventions: DRUG: AZD4041|DRUG: Itraconazole|DRUG: Buprenorphine|DRUG: Buprenorphine / Naloxone|DRUG: Hydromorphone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Nutrition Education Module to Modify Sugar Consumptions Among Individuals With Cardio Metabolic Risks
Status: NOT_YET_RECRUITING
Conditions: Cardiometabolic Syndrome
Interventions: BEHAVIORAL: Intervention Group (IG)|BEHAVIORAL: Control Group (CG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Impact of Virtual Reality and Kaleidoscope in Children During Vaccination
Status: COMPLETED
Conditions: Pain|Pediatric Patient|Fear|Virtual Reality|Nursing Caries
Interventions: PROCEDURE: VR|PROCEDURE: Kaleidoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Investigate Outcome of Individualized Treatment in Patients With Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Alectinib|DRUG: Cetuximab|DRUG: Crizotinib|DRUG: Dasatinib|DRUG: Everolimus|DRUG: Encorafenib|DRUG: Gemcitabine|DRUG: Idelalisib|DRUG: Larotrectinib|DRUG: Methotrexate|DRUG: Palbociclib|DRUG: Panobinostat|DRUG: Pembrolizumab|DRUG: Petrozumab|DRUG: Trastuzumab|DRUG: Talazoparib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Group Interval Fitness Program for Adolescents With Cognitive Impairments in the School Setting.
Status: NOT_YET_RECRUITING
Conditions: Cognitive Impairment
Interventions: OTHER: Group exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Effect of Selpercatinib (LY3527723) in Participants With Normal and Impaired Renal Function
Status: COMPLETED
Conditions: Healthy|Renal Insufficiency
Interventions: DRUG: Selpercatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: AFP464 in Treating Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: AFP464|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-escalation, Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Patients With r/r NHL and r/r B-cell ALL
Status: RECRUITING
Conditions: Non-Hodgkin Lymphoma|B-cell Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: Azer-cel|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: IL-2|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Stem Cell Rescue With CD133+ Selected Cells in High-Risk Neuroblastoma
Status: TERMINATED
Conditions: Neuroblastoma
Interventions: DRUG: Carboplatin|DRUG: Etoposide|DRUG: Melphalan|PROCEDURE: Stem Cell Infusion|DEVICE: ClinicMACS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: tDCS for Treatment Resistant Obsessive Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Active stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of The Safety and Efficacy Of Viagra In Men With Erectile Dysfunction Who Do Not Self Identify.
Status: COMPLETED
Conditions: Impotence
Interventions: DRUG: Placebo|DRUG: Viagra (sildenafil citrate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IBUPAP Study for Pain Management in Children
Status: COMPLETED
Conditions: Pain Management
Interventions: DRUG: Ibuprofen|DRUG: APAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Consistency of Electrical Cardiometry and Pulmonary Artery Catheter
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension|Right Ventricular Dysfunction
Interventions: BEHAVIORAL: passive leg raising|DRUG: dobutamine test|DRUG: inhaled nitric oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Casein Glycomacropeptide in Healthy Subjects
Status: COMPLETED
Conditions: Gastrointestinal Disease
Interventions: DIETARY_SUPPLEMENT: Casein glycomacropeptide|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efect of Quinoa and Flaxseed in Cititoxicity and Glicemic Control in Metabolic Syndrome Patients
Status: UNKNOWN
Conditions: Metabolic Syndrome|Nutritional and Metabolic Diseases
Interventions: OTHER: Quinoa|OTHER: Flaxseed|OTHER: Quinoa and Flaxseed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Gastric Lavage in Preventing Feeding Problems in Babies Born With Meconium Stained Amniotic Fluid
Status: COMPLETED
Conditions: Gastritis of Newborn|Other Vomiting of Newborn|Meconium in Amniotic Fluid
Interventions: PROCEDURE: Gastric lavage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nivolumab/Ipilimumab and Chemotherapy Combination in Advanced NSCLC Patients With HIV, HBV, HCV and Long Covid Syndrome
Status: NOT_YET_RECRUITING
Conditions: NSCLC Stage IV|HIV|HBV|HCV|Long COVID
Interventions: DRUG: Nivolumab and Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computed Tomography (CT) - Guided Brachytherapy Versus Transarterial Chemoembolization in Patients With Unresectable Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: CT-guided brachytherapy|PROCEDURE: transarterial chemoembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Activation Through Counseling, Exercise and Mobilization
Status: COMPLETED
Conditions: Pancreas Cancer|Biliary Tract Cancer|Non Small Cell Lung Cancer|Advanced Cancer
Interventions: BEHAVIORAL: Multimodal and exercise-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sacral Erector Spinae Plane Block(ESPB) in Lumbar Discectomy
Status: COMPLETED
Conditions: Pain Management
Interventions: PROCEDURE: sacral erector spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Immune Response of One Dose of OVX836 at Two Dose Levels, in Comparison to Influvac TetraTM, After Intramuscular Administration in Healthy Subjects Aged 18-65 Years
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: OVX836|BIOLOGICAL: Quadrivalent seasonal influenza vaccine (Influvac TetraTM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Online 1-Day CBT-Based Workshops for PPD
Status: COMPLETED
Conditions: Postpartum Depression
Interventions: BEHAVIORAL: Online 1-Day Cognitive Behavioural Therapy (CBT)-Based Workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Exenatide and Insulin Glargine in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: exenatide|DRUG: Insulin glargine|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of NKG2D-Ligand Targeted CAR-NK Cells in Patients With Metastatic Solid Tumours
Status: UNKNOWN
Conditions: Solid Tumours
Interventions: BIOLOGICAL: CAR-NK cells targeting NKG2D ligands
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pregabalin Premedication for Knee Arthroscopy
Status: UNKNOWN
Conditions: Knee Arthroscopy
Interventions: DRUG: Pregabalin (PG)|DRUG: Control placebo (C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Attentional Bias Modification Training for People With Chronic Musculoskeletal Pain
Status: UNKNOWN
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Attentional bias modification training (AMG)|BEHAVIORAL: Attentional bias placebo (ACG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Favipiravir 200 mg Film Tablet (World Medicine, Turkey) Under Fasting Conditions
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Test: Favipiravir 200 mg (LOQULAR)|DRUG: Reference: Favipiravir 200 mg (Avigan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Fasting Study of Levothyroxine Sodium Tablets 300 μg to Levothroid® Tablets 300 μg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Levothyroxine Sodium Tablets 300 μg|DRUG: Levothroid® Tablets 300 μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Relative Bioavailability and Tolerability of Various Experimental Formulations of BIBV 308 SE in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBV 308 SE solution|DRUG: BIBV 308 SE capsule 1|DRUG: BIBV 308 SE capsule 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Artificial Sweetener on Gastrointestinal (GI) Peptide Secretion
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Artificial sweeteners; Carbohydrate Sugars|DIETARY_SUPPLEMENT: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Metabolic Effects of Ultra-endurance Exercise and Training Under Low or High Glycaemic Index-carbohydrate Diets.
Status: COMPLETED
Conditions: A Randomised Counter-balanced Intervention Study in Endurance Athletes
Interventions: DIETARY_SUPPLEMENT: Isomaltulose|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Evaluation of the Outcomes of Bariatric Surgery - a Cohort Study
Status: RECRUITING
Conditions: Morbid Obesity
Interventions: PROCEDURE: Roux en Y gastric bypass|PROCEDURE: Sleeve gastrectomy|PROCEDURE: Gastric banding|PROCEDURE: Intragastric balloon
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preservation of Ovarian Cortex Tissue in Girls With Turner Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Fertility Preservation|Ovarian Tissue Cryopreservation|Turner Syndrome|Live Birth|Premature Ovarian Failure
Interventions: PROCEDURE: Ovarian tissue cryopreservation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of S-adenosylmethionine (SAMe) on Blood Levels of Homocysteine
Status: COMPLETED
Conditions: Hyperhomocysteinemia
Interventions: DIETARY_SUPPLEMENT: S-adenosylmethionine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Pf-06650833 In Subjects With Rheumatoid Arthritis, With An Inadequate Response To Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: PF-06650833|DRUG: Placebo|DRUG: Tofacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Ultrase® MT12 in Young Cystic Fibrosis Children (CF)
Status: COMPLETED
Conditions: Cystic Fibrosis|Pancreatic Insufficiency
Interventions: DRUG: Ultrase® MT12
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neo-adjuvant Nivolumab or Nivolumab With Ipilimumab in Advanced Cutaneous Squamous Cell Carcinoma Prior to Surgery
Status: RECRUITING
Conditions: Cutaneous Squamous Cell Carcinoma
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Cariprazine As Adjunctive Therapy In Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Antidepressant + placebo|DRUG: Antidepressant + cariprazine (0.1-0.3 mg/day)|DRUG: Antidepressant + cariprazine (1-2 mg/d)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Randomized Study of Lucinactant in Full Term Newborn Infants With Meconium Aspiration Syndrome
Status: TERMINATED
Conditions: Meconium Aspiration
Interventions: DRUG: Lucinactant|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thymoglobulin® Pharmacokinetics in Patients Undergoing Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Hematopoietic Stem Cell Transplantation-Associated Thrombotic Microangiopathy
Interventions: DRUG: Thymoglobulin 25 milligrams (mg) Injection|BIOLOGICAL: blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin and Incitement to Use Olfactory Stimuli in Restrictive Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia
Interventions: OTHER: olfactory workshop|OTHER: other workshop|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Role of Secretin on the Energy Homeostasis
Status: COMPLETED
Conditions: Obesity|Metabolic Disease|Diabetes|Adiposity
Interventions: DRUG: Secretin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Recall Enhancement Through Treatment With Atomoxetine in MS (RETAIN-MS)
Status: COMPLETED
Conditions: Memory Disorders|Multiple Sclerosis
Interventions: DRUG: Atomoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM)
Status: COMPLETED
Conditions: Tuberous Sclerosis Complex (TSC)|Lymphangioleiomyomatosis (LAM)
Interventions: DRUG: Everolimus (RAD001)|DRUG: Everolimus Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioavailability of Cefzil 250 mg/5 ml Cefprozil Oral Suspension Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cefprozil 250 mg/5 ml Oral Suspension (Sandoz, Austria)|DRUG: Cefzil (Cefprozil) 250 mg/5 ml Oral Suspension (Bristol-Myers Squibb, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Automated Distal Vascular Anastomosis in Coronary Surgery: Phase II
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Automated distal anastomotic device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Circulatory I-FABP in Elderly Persons in Daily Life
Status: COMPLETED
Conditions: Malnutrition|Intestinal Integrity|Intestinal Fatty Acid Binding Protein (IFABP)
Interventions: BEHAVIORAL: Walking test|BEHAVIORAL: Standard Meal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Induction of Opioid-Dependent Individuals Onto Buprenorphine and Buprenorphine/Naloxone
Status: COMPLETED
Conditions: Opioid-related Disorders
Interventions: DRUG: Buprenorphine soluble film|DRUG: Buprenorphine/naloxone film strip|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Sexual Quality of Life - Randomized Trial of Two vs Five MRI Guided SABR Treatments for Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Cancer of Prostate|Prostate Adenocarcinoma
Interventions: RADIATION: Stereotactic Ablative Body Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Levodopa on Cardiovascular Autonomic Function in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Orthostatic Hypotension
Interventions: DRUG: Autonomic testing on and off levodopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Prevalence and Predictors of Prolonged Post-surgical Opioid Use: a Prospective Observational Cohort Study
Status: COMPLETED
Conditions: Opioid Use Disorders|Opioid-related Disorders|Surgery|Pain, Postoperative|Post-operative Complications|Opiate Addiction
Interventions: OTHER: Continued use of opioid analgesics >90 days post-surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pragmatic Set of Interventions Versus Scapular Strengthening Exercises on Scapular Dyskinesia in Adhesive Capsulitis
Status: RECRUITING
Conditions: Scapular Dyskinesis|Adhesive Capsulitis
Interventions: OTHER: pragmatic set of interventipons|OTHER: scapular strengthening exercise.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Self-Expanding Nitinol S.M.A.R.T CONTROL Stent Versus Life Stent For The Atherosclerotic Femoro-Popliteal Arterial Disease
Status: UNKNOWN
Conditions: Peripheral Arterial Disease|Atherosclerosis
Interventions: DEVICE: S.M.A.R.T CONTROL Stent|DEVICE: LifeStent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Angiogenic Therapy Post Transplant (ASCR) for Pediatric Solid Tumors
Status: COMPLETED
Conditions: Glioma|Neuroectodermal Tumors, Primitive|Wilms Tumor|Rhabdomyosarcoma|Sarcoma, Ewing|Osteosarcoma|Retinoblastoma
Interventions: DRUG: Metronomic Cyclophosphamide|DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Nanofat Grafting by Injection Versus With Microneedling in Post-burn and Traumatic Atrophic Scars
Status: RECRUITING
Conditions: Scars
Interventions: PROCEDURE: injection of autologous nanofat grafting|PROCEDURE: microneedling with autologus nanofat graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrated Clinical Decision Support for Empiric Antibiotic Selection in Sepsis
Status: NOT_YET_RECRUITING
Conditions: Sepsis|Bacterial Infections|Community-Acquired Infections|Hospital Infection
Interventions: OTHER: Clinical Decision Support Algorithm for Empiric Antibiotics in Sepsis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Core Stability Exercises in Patients With Patellofemoral Pain Syndrome
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Core stability exercises|OTHER: Conventional Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effects of Carbohydrate-electrolyte Solution on Metabolic Responses in Paediatric Patients
Status: RECRUITING
Conditions: Fasting
Interventions: OTHER: Oral carbohydrate-electrolyte solution|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Dienogest Versus Oral Contraceptive Pills on Pain Associated With Endometriosis
Status: UNKNOWN
Conditions: Endometriosis
Interventions: DRUG: Dienogest 2 MG Oral Tablet|DRUG: Yasmin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Anacetrapib (MK-0859) When Added to Ongoing Statin Therapy (MK-0859-021)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Anacetrapib 100 mg|DRUG: Placebo for anacetrapib 100 mg|DRUG: Anacetrapib 25 mg|DRUG: Placebo for anacetrapib 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cloxacillin as Prevention of Double Lumen Infection in Hemodialysis Patients
Status: COMPLETED
Conditions: Double Lumen Infection|Hemodialysis
Interventions: DRUG: cloxacillin|DRUG: heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Performance and Bioavailability Study of Entrectinib in Healthy Volunteers.
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: Entrectinib 600 mg (T1)|DRUG: Entrectinib 600 mg (T2)|DRUG: Entrectinib 200 mg (R)|DRUG: Entrectinib 200 mg (T)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 24 vs 48 Weeks of Pegetron® (Peginterferon Alfa-2b + Ribavirin) in Naïve Genotype 1 Hepatitis C (Study P05016)(TERMINATED)
Status: TERMINATED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Combination of pegylated interferon alfa-2b (PEG) and ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of M118 in Percutaneous Coronary Intervention (EMINENCE)
Status: COMPLETED
Conditions: Coronary Artery Disease (CAD)
Interventions: DRUG: M118|DRUG: Unfractionated Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pupillometry Guided Remifentanil Administration and Total Opioid Consumption During Propofol - Remifentanil TCI
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: Videopupillometer Algiscan|OTHER: Standard practice|DRUG: Propofol|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study in Indian Postmenopausal Women With Osteoporosis to Evaluate the Efficacy and Safety of Denosumab
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: denosumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Creatine Combined With Curcumin in the Intervention of Early Cachexia in Upper Gastrointestinal Tumors
Status: NOT_YET_RECRUITING
Conditions: Stage IV Gastric Cancer|Stage IIIA Gastric Cancer|Stage IIIB Gastric Cancer|Stage III Esophageal Cancer|Stage IV Esophageal Cancer
Interventions: DIETARY_SUPPLEMENT: basic nutrition|DIETARY_SUPPLEMENT: oral supplement of creatine and curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Climacteric Clinical Trial : the Use of Complementary Therapy and Hormonal Replacement
Status: UNKNOWN
Conditions: Climacteric
Interventions: OTHER: flower therapy|OTHER: therapeutic touch|OTHER: auricular therapy|DRUG: Hormones
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SMARTHealth Diabetes in China Using Lay Family Health Promoters
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Hypertension|Dyslipidemias
Interventions: BEHAVIORAL: SMARTHealth Diabetes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PROTECT: Prospective Trial on Erythropoietin in Clinical Transplantation
Status: COMPLETED
Conditions: Patients Receiving a Kidney From a Non-Heart-Beating Donor
Interventions: DRUG: Epoetin beta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dexamethasone for Treating Severe Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype
Status: NOT_YET_RECRUITING
Conditions: Hospital Acquired Pneumonia
Interventions: DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Centre Study to Evaluate the Safety and Immunogenicity of the Human Papillomavirus Vaccine (GSK-580299) in Chinese Females
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: GSK580299 (Cervarix™ , HPV -16/18 L1 VLP AS04 vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impacts of Alcohol Warning Labels: An Online Experiment
Status: NOT_YET_RECRUITING
Conditions: Alcohol Drinking
Interventions: BEHAVIORAL: Liver Cancer|BEHAVIORAL: Throat and Mouth Cancer|BEHAVIORAL: Colorectal Cancer|BEHAVIORAL: Multiple Cancers|BEHAVIORAL: Liver Disease|BEHAVIORAL: Hypertension|BEHAVIORAL: Dementia|BEHAVIORAL: Drinking Guidelines|BEHAVIORAL: Current Warning|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pregnenolone Augmentation in the Treatment of Patients With Recent-Onset Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizophreniform Disorder|Schizoaffective Disorders
Interventions: DIETARY_SUPPLEMENT: Pregnenolone|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Gemcitabine and Erlotinib As Adjuvant Therapy In Patients With Resected Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CTC Detection Rate in SCCHN With a in Vivo Device
Status: UNKNOWN
Conditions: Circulating Tumor Cell|Squamous Cell Carcinoma of the Head and Neck
Interventions: DIAGNOSTIC_TEST: circulating tumor cell analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Immunogenicity of Recombinant Hepatitis B Vaccine Sci-B-Vac® Compared to Engerix-B®
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: Sci-B-Vac®|BIOLOGICAL: Engerix-B®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ALSENLITE: Senolytics for Alzheimer's Disease
Status: ENROLLING_BY_INVITATION
Conditions: Mild Cognitive Impairment|Alzheimer Disease
Interventions: DRUG: Dasatinib|DRUG: Quercetin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT