pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intensive Weight Loss Intervention Versus Bariatric Surgery for Adults With Severe and Complex Obesity: the LightBAR Randomised Trial
Status: RECRUITING
Conditions: Obesity
Interventions: BEHAVIORAL: Intensive weight loss intervention|PROCEDURE: Bariatric surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prediction of Neonatal Respiratory Distress Syndrome in Preterm Fetuses by Assessment of Fetal Lung Volume by Vocal and Pulmonary Artery Resistance Index a Pilot Study
Status: COMPLETED
Conditions: Fetal Lung Volume of Preterm Fetuses Measured by VOCAL, PA-RI Measured by Pulsed Doppler
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Type 1 Diabetes Impacts of Semaglutide on Cardiovascular Outcomes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Semaglutide Pen Injector|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diet, Insulin Sensitivity And the Brain
Status: COMPLETED
Conditions: Obesity|Diabetes Mellitus Type 2
Interventions: OTHER: Meal size increase with HFHS|OTHER: Meal size increase with HS|OTHER: Meal frequency increase with HFHS|OTHER: Meal frequency increase with HS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A 6-month Efficacy, Safety, and Tolerability Study of Rifaximin In Preventing Hepatic Encephalopathy
Status: COMPLETED
Conditions: Hepatic Encephalopathy
Interventions: DRUG: Rifaximin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Entrainment Between Clinician and Patient During Palpation
Status: COMPLETED
Conditions: Doctor Patient Relation
Interventions: PROCEDURE: CV4|PROCEDURE: touching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Post-natal Post-traumatic Stress: Impact of an Early Dyadic Intervention Though Interaction Guidance Therapy on Maternal Sensitivity and Reduction of Maternal Stress
Status: RECRUITING
Conditions: Post-traumatic Stress Disorder (PTSD)
Interventions: BEHAVIORAL: Interaction Guidance Therapy|BEHAVIORAL: Mother's child psychotherapeutic session|BEHAVIORAL: Interview|BEHAVIORAL: Self-rated questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Obstructive Sleep Apnea Management Via Wireless Telemonitoring
Status: COMPLETED
Conditions: Sleep Apnea Syndromes
Interventions: BEHAVIORAL: Self-management|BEHAVIORAL: Telemonitored care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: OROS Methylphenidate (Concerta) in the Treatment of Adult ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: OROS methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SWC for Treatment of Superficial Partial-Thickness Burns
Status: RECRUITING
Conditions: Burn Wounds
Interventions: DEVICE: SynePure Wound Cleanser and Catasyn Advanced Technology Hydrogel|DRUG: SILVADENE Cream 1% (silver sulfadiazine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of Hard-to-Heal DFUs
Status: RECRUITING
Conditions: Diabetic Foot Ulcer (DFU)|Ulcer Foot|Diabetic Foot|Foot Ulcer
Interventions: OTHER: Standard of Care|OTHER: Revita|OTHER: Relese|OTHER: Cogenex|OTHER: Enverse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INTense ExeRcise for surviVAL Among Men With Metastatic Prostate Cancer (INTERVAL - GAP4)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Prostate Cancer
Interventions: BEHAVIORAL: High intensity aerobic and resistance training|BEHAVIORAL: Psychosocial support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: vNOTES Salpingo-oophorectomy or Bilateral Salpingectomy Compared With Laparoscopic.
Status: TERMINATED
Conditions: Salpingectomy
Interventions: PROCEDURE: VNOTES|PROCEDURE: laparoscopic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Fibrin Sealant Grifols (FS Grifols) During Soft Tissue Open Surgeries
Status: COMPLETED
Conditions: Soft Tissue Surgical Bleeding
Interventions: BIOLOGICAL: Fibrin Sealant (FS) Grifols|DEVICE: Surgicel®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Nivolumab in Patients With Classical Hodgkin's Lymphoma (Registrational)
Status: COMPLETED
Conditions: Hodgkin Disease
Interventions: DRUG: Nivolumab|DRUG: Doxorubicin|DRUG: Vinblastine|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Efficacy of Sodium Thiosulfate (BYON5667) Eye Drops to Reduce Ocular Toxicity in Cancer Patients Treated With SYD985
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: BYON5667 & SYD985|DRUG: Placebo & SYD985
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess Pharmacokinetics of Accordion Pill Carbidopa-Levodopa Compared to Immediate Release Carbidopa-Levodopa in Parkinson's Disease Patients
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DRUG: Accordion Pill Carbidopa/Levodopa|DRUG: Sinemet CR 25Mg-100Mg Extended-Release Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Acceptability Study of the UC-781 Microbicide Gel Applied Rectally
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: UC-781 microbicide gel (0.1% and 0.25%)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Phase III Randomized Double-Blind Placebo Controlled Study To Evaluate the Safety and Efficacy of Betaseron in AIDS and Advanced ARC Patients Receiving a Reduced-Dose AZT Regimen
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Interferon beta-1b|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Long-term Outcome of General Anesthesia on Dysgnosia
Status: UNKNOWN
Conditions: Delirium,|Dementia,|Amnestic,|Cognitive Disorders
Interventions: DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Covered Metal Stent for Benign Biliary Stricture Caused by Chronic Pancreatitis
Status: UNKNOWN
Conditions: Biliary Stricture|Chronic Pancreatitis
Interventions: PROCEDURE: ERCP|DEVICE: covered self-expanding biliary metal stent, 12mm in diameter|DEVICE: covered self-expanding biliary metal stent, 10mm in diameter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Psychotherapy for Perinatal Bipolar Disorder
Status: TERMINATED
Conditions: Bipolar Disorder
Interventions: BEHAVIORAL: Interpersonal and Social Rhythm Therapy|BEHAVIORAL: Enhanced Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Biologic Mesh vs Bioabsorbable Mesh During Ventral Hernia Repair in At-risk Patients
Status: TERMINATED
Conditions: Ventral Hernia
Interventions: DEVICE: Strattice Arm|DEVICE: Bio-A Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized, Phase III Trial of FLAC (5-Fluorouracil, Leucovorin, Adriamycin, Cytoxan) Chemotherapy With GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor) Versus PIXY 321 in Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Fever|Hematologic Diseases|Neutropenia|Sepsis
Interventions: DRUG: FLAC chemotherapy with GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: PCME Prevention in Patients With NPDR
Status: COMPLETED
Conditions: Cystoid Macular Edema Following Cataract Surgery
Interventions: DRUG: Bromfenac Ophthalmic 0.09% Ophthalmic Solution|DRUG: Dexamethasone Ophthalmic|DRUG: Placebo|PROCEDURE: Phacoemulsification surgery (PHACO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Reduction of Adverse Events of Anticholinergic Drugs by Multidisciplinary Medical Reviews in Norwegian Nursing Homes
Status: COMPLETED
Conditions: Anticholinergic Side Effects
Interventions: OTHER: Multidisciplinary drug reviews by pharmacist and physician
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of MK-0476 in Adult Patients With Acute Asthma (0476-334)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: montelukast sodium|DRUG: montelukast sodium|DRUG: aminophylline hydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuing Cetuximab Plus Chemotherapy After First Progression in Wild-type KRAS, NRAS and BRAF V600E Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Wild-type KRAS,NRAS and BRAF V600E Metastatic Colorectal Cancer
Interventions: DRUG: Cetuximab combind mFOLFOX6/FOLFIRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating the Efficacy and Safety of Triptergium Wilfordii and Acitretin in Psoriasis Vulgaris - CHINA201002016-2
Status: UNKNOWN
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Triptergium Wilfordii|DRUG: Acitretin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Two CGM Systems Tested Simultaneously in Ambulatory Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Blood Glucose
Interventions: DEVICE: Guardian Enlite sensor|DEVICE: Dexcom G4 platinum sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regorafenib in Indian Patients With Metastatic Colorectal Cancer (mCRC).
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Regorafenib (Stivarga, BAY73-4506)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intradialytic Parenteral Nutrition on Nutritional Status and Quality of Life in Hemodialysis Patients
Status: UNKNOWN
Conditions: End Stage Renal Disease|Malnutrition|Sarcopenia|Hemodialysis Complication
Interventions: DRUG: Olimel N12|DRUG: Glucose IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of HBAI20 Hepatitis B Vaccine in Naive Adults and Non-responders
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: HBVaxPro|BIOLOGICAL: HBAI20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Guided Cartilage Regeneration Membrane
Status: UNKNOWN
Conditions: Articular Cartilage Injury|Knee Ligament Injury
Interventions: COMBINATION_PRODUCT: Guided cartilage regeneration membrane|PROCEDURE: Microfracture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of the Spinal Manipulation on Muscle Spasticity and Manual Dexterity in Cerebral Palsy.
Status: COMPLETED
Conditions: Cerebral Palsy, Spastic
Interventions: PROCEDURE: Spinal manipulation|PROCEDURE: Imitation of the spinal manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Evaluate the Safety, Tolerability and Pharmacokinetics of K0706 in Plasma and Cerebrospinal Fluid in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: K0706|DRUG: K0706|DRUG: K0706
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inflammatory Response to Aortic Valve Replacement
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: PROCEDURE: Transarterial aortic valve implantation - TAVI|PROCEDURE: Surgical aortic valve replacement - SAVR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Bortezomib (Velcade(R)) in Patients With Advanced Waldenström Macroglobulinemia
Status: COMPLETED
Conditions: Waldenstrom Macroglobulinemia
Interventions: DRUG: BORTEZOMIB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Three Mechanical Systems on Removal of Endotoxins From Necrotic Teeth
Status: UNKNOWN
Conditions: Endodontic Disease
Interventions: DIAGNOSTIC_TEST: ProTaper Next
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methylphenidate to Treat Methamphetamine Dependence
Status: UNKNOWN
Conditions: Methamphetamine Dependence
Interventions: DRUG: methylphenidate|DRUG: Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Randomized Controlled Trial of a Breathlessness Intervention Service for Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Dyspnea
Interventions: BEHAVIORAL: Breathlessness Intervention Service (BIS)|BEHAVIORAL: Best supportive care (Standard care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Phase II Trial of Targeted Radiation With no Castration for Mcrpc
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: stereotactic ablative radiotherapy|DRUG: Pluvicto|DRUG: topical testosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ribavirin and Hedgehog Inhibitor With or Without Decitabine in AML
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Ribavirin|DRUG: Vismodegib|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Follow Up of Subjects Enrolled in Randomized Trial of Prenatal and Infancy Home Visitation
Status: COMPLETED
Conditions: Risk Reduction Behavior|Reproductive Behavior
Interventions: BEHAVIORAL: nurse home visitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: L-PRF Plus Non Surgical Periodontal Treatment
Status: COMPLETED
Conditions: Periodontitis
Interventions: PROCEDURE: Leukocyte and platelet rich fibrin|PROCEDURE: Non-Surgical Periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Pressure Telemonitoring and Goal Blood Pressure in Diabetes
Status: COMPLETED
Conditions: Diabetes|Hypertension
Interventions: DEVICE: Blood pressure monitor with telemetry|DEVICE: Home blood pressure monitor without telemetry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Mesothelin-Targeted Immunotoxin LMB-100 in Combination With Tofacitinib in Persons With Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and Other Mesothelin Expressing Solid Tumors
Status: COMPLETED
Conditions: Neoplasms With Mesothelin Expression|Epithelioid Mesothelioma|Cholangiocarcinoma, Extrahepatic|Adenocarcinoma, Pancreatic
Interventions: DRUG: LMB-100|DRUG: Tofacitinib|DEVICE: Mesothelin Expression
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy Between Fractional Microneedling Radiofrequency and Bipolar Radiofrequency for Acne Scar
Status: COMPLETED
Conditions: Acne|Scar
Interventions: DEVICE: microneedling radiofrequency device|DEVICE: bipolar radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Budesonide From Ekmasonid 9 mg Extended Release FCT (Hikma Pharma, Egypt) Versus Uceris 9 mg Extended Release Tablets (Man. for: Salix Pharm., a Division of Valeant Pharm. LLC, USA, by: Cosmo S.P.A., Italy by License of Cosmo Tech. Ltd., Ireland, Product of France)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ekmasonid|DRUG: Uceris (first dose)|DRUG: Uceris (second dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Menier's Disease - Bone Density Study
Status: NOT_YET_RECRUITING
Conditions: Meniere Disease|Osteoporosis|Osteopenia|Vitamin D Deficiency|Vestibular Disorder
Interventions: DIAGNOSTIC_TEST: vitamin D plasma levels baseline|DIAGNOSTIC_TEST: Dual-energy X-ray absorptiometry at baseline|DIAGNOSTIC_TEST: cervical Vestibular evoked myogenic potentials at baseline|DIAGNOSTIC_TEST: Audiogram at baseline|DIAGNOSTIC_TEST: Measuring Orthostatic Blood Pressure at baseline|DIAGNOSTIC_TEST: cold pressor test at baseline|DIAGNOSTIC_TEST: vitamin D plasma levels one year after recruitment|DIAGNOSTIC_TEST: vitamin D plasma levels two years after recruitment|DIAGNOSTIC_TEST: Dual-energy X-ray absorptiometry one year after recruitment|DIAGNOSTIC_TEST: Dual-energy X-ray absorptiometry two years after recruitment|DIAGNOSTIC_TEST: cervical Vestibular evoked myogenic potentials one year after recruitment|DIAGNOSTIC_TEST: cervical Vestibular evoked myogenic potentials two years after recruitment|DIAGNOSTIC_TEST: Audiogram one year after recruitment|DIAGNOSTIC_TEST: Audiogram two years after recruitment|DIAGNOSTIC_TEST: Measuring Orthostatic Blood Pressure one year after recruitment|DIAGNOSTIC_TEST: Measuring Orthostatic Blood Pressure two years after recruitment|DIAGNOSTIC_TEST: cold pressor test one year after recruitment|DIAGNOSTIC_TEST: cold pressor test two years after recruitment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: To Evaluate the Efficacy and Safety of the Transfemoral Mitral Valve Repair System in the Treatment of Patients With Moderately Severe and Severe Functional Mitral Regurgitation(FMR) Who Remained Clinically Symptomatic After Guideline-directed Medical Treatment
Status: NOT_YET_RECRUITING
Conditions: Mitral Valve Insufficiency
Interventions: DEVICE: Transfemoral mitral-valve repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Balloon Guide Catheter in Mechanical Thrombectomy Patients
Status: UNKNOWN
Conditions: Mechanical Thrombectomy|Stroke|Balloon Guide Catheter
Interventions: DEVICE: Balloon guide catheter|DEVICE: Non-balloon guide catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study in Healthy Male Subjects Designed to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C] LC15-0444
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [14C]-LC15-0444
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Metformin Hydrochloride in Treating Patients With Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: capecitabine|DRUG: cisplatin|DRUG: epirubicin|DRUG: gemcitabine|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Herpetic Eye Disease Study (HEDS) I
Status: UNKNOWN
Conditions: Keratitis, Herpetic|Ocular Herpes Simplex
Interventions: DRUG: Prednisolone Phosphate|DRUG: Acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Post-operative Radiotherapy Omission in Selected Patients With Early Breast Cancer Trial International VErsion
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Breast Cancer Female
Interventions: RADIATION: Arm A: Radiotherapy Omission|OTHER: Arm B: Standard Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TK216 and Decitabine in Treating Patients With Relapsed and Refractory Acute Myeloid Leukemia
Status: WITHDRAWN
Conditions: Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Group 1: TK216|DRUG: Group 2: TK216|DRUG: Part 2: Decitabine 10mg/m2|DRUG: Part 2: Decitabine 20 mg/m2|DRUG: Expansion Phase TK216|DRUG: Expansion Phase Decitabine|DRUG: Part 2: TK216
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of a Standardised High Fat Breakfast on the Bioavailability of BI 14332 CL in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 14332 CL|OTHER: high fat breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate of the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Ruxolitinib cream|DRUG: Vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Autologous Cord Blood Mononuclear Cells for Treatment of Bronchopulmonary Dysplasia in Extremely Preterm Neonates
Status: UNKNOWN
Conditions: BPD
Interventions: BIOLOGICAL: autologous cord blood mononuclear cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Myeloproliferative Neoplasms (MPNs) Patient Registry
Status: RECRUITING
Conditions: Primary Myelofibrosis|Polycythemia Vera|Essential Thrombocythemia|Mastocytosis|Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative|Leukemia, Myelomonocytic, Juvenile|Chronic Eosinophilic Leukemia-not Otherwise Specified|Myelodysplastic-Myeloproliferative Diseases|Neoplasms|Leukemia, Myelomonocytic, Chronic
Interventions: OTHER: Observational
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Mother-infant Skin-to-skin Contact on Stress Response of Preterm Infants
Status: NOT_YET_RECRUITING
Conditions: Preterm Infant
Interventions: BEHAVIORAL: Skin-to-skin contact|OTHER: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Therapy With NC-6004 and Gemcitabine in Advanced Solid Tumors or Non-Small Cell Lung, Biliary and Bladder Cancer
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: NC-6004|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cabazitaxel Plus Prednisone With Octreotide For Castration-Resistant Prostate Cancer (CRPC) Previously Treated With Docetaxel
Status: TERMINATED
Conditions: Diarrhea|Hormone-resistant Prostate Cancer|Recurrent Prostate Cancer|Stage I Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer|Stage III Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: cabazitaxel|DRUG: prednisone|DRUG: octreotide pamoate|OTHER: questionnaire administration|DRUG: octreotide acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Mode of Contraction on Neuromuscular Fatigue
Status: RECRUITING
Conditions: Volunteers
Interventions: BEHAVIORAL: Mini Mental State Examination|DIAGNOSTIC_TEST: 6 Minutes Walk Test|DIAGNOSTIC_TEST: Timed up and go|DIAGNOSTIC_TEST: Isokinetic Body weight-based quadriceps intermittent fatigue test (BW-QIF Test)|DIAGNOSTIC_TEST: Cycloergometer body weight-based quadriceps intermittent fatigue test (BW-QIF Test)|DIAGNOSTIC_TEST: Isometric BW-QIF Test (Body weight-based quadriceps intermittent fatigue test)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treatment of Post-Punch Biopsy Bleeding in Anticoagulated Patients Using Self-Administered BXP154
Status: COMPLETED
Conditions: Wound Bleeding
Interventions: DRUG: BXP154|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Supporting Adolescents to Adhere - an Intervention Using Airtime Rewards Allocated by a Prize Drawing
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: BEHAVIORAL: Own Adherence Group|BEHAVIORAL: Fixed Adherence Group|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hematopoietic Stem Cell Support in Patients With Refractory Sarcoidosis
Status: TERMINATED
Conditions: Sarcoidosis
Interventions: BIOLOGICAL: Autologous hematopoietic stem cell transplantation|BIOLOGICAL: Allogeneic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Intraperitoneal Floxuridine Added to Chemoradiation for Fully Resected Advanced Stomach Cancer
Status: COMPLETED
Conditions: Gastric Cancer|Stomach Cancer
Interventions: PROCEDURE: Potentially curative surgery|DRUG: Floxuridine (IP)|PROCEDURE: Adjuvant Chemoradiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Intermittent Hypoxia on Acute Hypoxic Injury
Status: RECRUITING
Conditions: Acute Mountain Sickness
Interventions: OTHER: Intermittent Hypoxia|OTHER: Sham Intermittent Hypoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: 177Lu-PSMA-EB-01 in Patients With Metastatic Castration-resistant Prostate Cancer
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: 1.11 GBq (30 mCi) of 177Lu-PSMA-EB-01|DRUG: 1.85 GBq (50 mCi) of 177Lu-PSMA-EB-01|DRUG: 2.59 GBq (70 mCi) of 177Lu-PSMA-EB-01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cholecalciferol Intervention to Prevent Respiratory Infections Study
Status: COMPLETED
Conditions: Respiratory Tract Infection|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Probiotics for Prevention of Antibiotic Associated Diarrhea and Clostridium Difficile Associated Disease
Status: TERMINATED
Conditions: Diarrhea
Interventions: DIETARY_SUPPLEMENT: Probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Single Treatment With FT1050 of an Ex-vivo Modulated Umbilical Cord Blood Unit
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma (NHL)|Hodgkin's Disease|Chronic Lymphocytic Leukemia (CLL)|Acute Myelogenous Leukemia (AML)|Acute Lymphoblastic Leukemia (ALL)
Interventions: BIOLOGICAL: Single FT1050 treated UCB unit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Onset of Effect and Time Course of Change in Lung Function With Benralizumab in Severe, Uncontrolled Asthma Patients With Eosinophilic Inflammation
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Benralizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Arm Exercise Capacity and Maximal Oxygen Consumption With Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Upper Extremity|Oxygen Consumption|Healthy
Interventions: DIAGNOSTIC_TEST: Maximal Exercise Capacity, Maximal Oxygen Consumption (VO2max)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multicenter Study of Hypofractionated Postoperative Radiotherapy in Patients Diagnosed With Prostate Carcinoma
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: hypofractionated postoperative radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using a Contact Dermatitis Model With Biologic Medications to Study Skin Inflammation
Status: RECRUITING
Conditions: Skin Inflammation|Allergic Contact Dermatitis
Interventions: DRUG: Squaric Acid Dibutyl Ester|OTHER: Known patch test allergens|DRUG: Dupilumab|DRUG: Adalimumab|DRUG: Ustekinumab|DRUG: Guselkumab|DRUG: Canakinumab|DRUG: Sarilumab|DRUG: Triamcinolone Acetonide|DRUG: Betamethasone Valerate|DRUG: Fluticasone Propionate|DEVICE: Microneedle|DEVICE: Suction blistering|PROCEDURE: Skin punch biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Equivalence of a Terconazole Vaginal Suppository (Test Product) Compared to the Reference Terconazole Vaginal Suppository in the Treatment of Vulvovaginal Candidiasis
Status: COMPLETED
Conditions: Vulvovaginal Candidiasis
Interventions: DRUG: Terconazole Vaginal Suppository|DRUG: Terazol Vaginal Suppository
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dexmedetomidine/Lidocaine/Intrathecal Morphine on Cancer Metastasis Biomarker After Colorectal Surgery
Status: COMPLETED
Conditions: Colorectal Cancer|Anesthesia|Cancer Metastatic|Inflammation
Interventions: DRUG: Lidocaine IV|DRUG: Dexmedetomidine IV|DRUG: intrathecal morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Efficacy of Skål Pro Powder on Symptoms of Irritable Bowel Syndrome
Status: NOT_YET_RECRUITING
Conditions: Irritable Bowel Syndrome|Gastrointestinal Diseases|Colonic Diseases, Functional|Intestinal Disease|Digestive System Disease|Pathologic Processes|Colonic Disease|Disease
Interventions: COMBINATION_PRODUCT: Skal Pro|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of Carperitide in Patients With Congestive Heart Failure
Status: COMPLETED
Conditions: Heart Failure, Congestive|Heart Decompensation|Left Ventricular Failure|Myocardiopathies|Systolic or Diastolic Left Ventricular Dysfunction
Interventions: DRUG: Carperitide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-operative Neoadjuvant Therapy Combined With Surgery for Treating Stage III Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma Stage III
Interventions: PROCEDURE: Transhepatic Arterial Chemotherapy And Embolization (TACE)|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Thoracolumbar Fascia Length
Status: COMPLETED
Conditions: Fascia
Interventions: DIAGNOSTIC_TEST: Visual Analogue Scale|DIAGNOSTIC_TEST: posterior capsule tightness|DIAGNOSTIC_TEST: shortness tests for lumbar movements|DIAGNOSTIC_TEST: range of motion tests for lumbar movements|DIAGNOSTIC_TEST: The thoracolumbar fascia length test|DIAGNOSTIC_TEST: Modify Schober test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Direct Transfer to Angiography Suite vs. Computed Tomography Suite in Endovascular Treatment: Randomized Clinical Trial (ANGIOCAT)
Status: TERMINATED
Conditions: Stroke, Acute
Interventions: OTHER: Direct Transfer to Angio Suite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid in On-pump CABG With Premature Clopidogrel Cessation
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Artery Bypass Graft
Interventions: DRUG: Tranexamic Acid|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ginger for Colorectal Cancer Prevention
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Ginger Root Extract (Pure Encapsulations)|DIETARY_SUPPLEMENT: Placebo Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: RAD001 and Lenalidomide in the Treatment of Subjects With Relapsed and Relapsed/Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: RAD001|DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Universal CD19-Targeted UCAR-NK Cells Combined With HSCT for B Cell Hematologic Malignancies
Status: RECRUITING
Conditions: B-Cell Lymphoblastic Leukemia/Lymphoma
Interventions: BIOLOGICAL: Anti-CD19 UCAR-NK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dysport® Treatment of Urinary Incontinence in Adults Subjects With Neurogenic Detrusor Overactivity (NDO) Due to Spinal Cord Injury or Multiple Sclerosis - Study 1
Status: TERMINATED
Conditions: Urinary Incontinence|Overactive Bladder
Interventions: BIOLOGICAL: Botulinum toxin type A|BIOLOGICAL: Botulinum toxin type A|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Finding Pharmacokinetic Study of the Tumour-targeting Human L19IL2 Monoclonal Antibody-Cytokine Fusion Protein in Patients With Advanced Solid Tumours
Status: COMPLETED
Conditions: Advanced Solid Tumours
Interventions: DRUG: L19IL2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lyophilized Fecal Microbiota Transplantation for Recurrent Clostridium Difficile Infection
Status: UNKNOWN
Conditions: Clostridium Difficile Infection
Interventions: DRUG: Lyophilized Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Phase II Study of Adjuvant Concurrent Radiation and Chemotherapy Versus Radiation Alone in Resected High-Risk Malignant Salivary Gland Tumors
Status: COMPLETED
Conditions: Malignant Salivary Gland Tumors
Interventions: DRUG: Cisplatin: 40 mg/m2 weekly during radiation|RADIATION: Radiation: 60-66 Gy in 2 Gy daily fractions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pegaptanib for Retinal Edema Secondary to Diabetic Vascular Disease(Preserve) Study
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Macugen® pegaptanib sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neural Predictors and Neural Changes Associated With Cognitive Behavior Therapy for Obssesive Compulsive Disorder
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder (OCD)
Interventions: BEHAVIORAL: Cognitive-behavior therapy (psychological treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetic Study to Compare Itepekimab Exposure When Administered With an Autoinjector Versus Prefilled Syringe
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Itepekimab AI|DRUG: Itepekimab PFS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Acceptability and Usability of a New Device for Intradermal Vaccination
Status: COMPLETED
Conditions: Pain|Vaccination Adverse Event
Interventions: DEVICE: Intradermal injection in the forearm (0,1cc NaCl 0,9%)|DEVICE: Intradermal injection in the upper arm (0,1cc NaCl 0,9%)|DRUG: Intramuscular injection in the upper arm (0,5cc NaCl 0,9%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Collagen Membrane in Guided Bone Regeneration
Status: UNKNOWN
Conditions: Cystectomy|Segmental Growing of Alveolar Tissue|Sinus Lift|Root Amputation and Apicoectomy|Periimplantitis
Interventions: DEVICE: HYPRO SORB F
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caudal Epidural Prolotherapy Versus Steroids in Failed Back Surgery Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain Syndrome
Interventions: DRUG: medthylprednisolone|DRUG: prolotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lidocaine and Neuroma Pain Related Modalities
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: Lidocaine (Xylocaine)|DIETARY_SUPPLEMENT: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Therapeutic Thoracentesis for Patients With Congestive Heart Failure and Large Pleural Effusion
Status: COMPLETED
Conditions: Congestive Heart Failure|Transudative Pleural Effusion
Interventions: PROCEDURE: Therapeutic thoracentesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Analgesic Efficacy of Wound Infiltration With Tramadol
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Different Physiotherapy Practices in Temporomandibular Disorders
Status: COMPLETED
Conditions: Temporomandibular Disorder
Interventions: OTHER: High voltage electrical stimulation+exercise therapy|OTHER: Exercise therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Radiation Therapy With or Without Chemotherapy for Endometrial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Cancer
Interventions: RADIATION: Radiation Therapy|DRUG: cisplatin|DRUG: carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bausch & Lomb Ophthalmic Viscosurgical Device (OVD) Dispersive (DVisc40)
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Bausch & Lomb DVisc40|DEVICE: Alcon VISCOAT®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clonidine is Better Than Zopiclone for Insomnia Treatment in Chronic Pain Patients
Status: COMPLETED
Conditions: Insomnia Chronic|Pain, Chronic
Interventions: DRUG: Clonidine 0.1mg pill|DRUG: Clonidine 0.2mg pill|DRUG: Zopiclone 3.75mg pill|DRUG: Zopiclone 7.5mg pill
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Paclitaxel, Doxorubicin, and Cyclophosphamide With Or Without Carboplatin in Treating Women With Locally Advanced Breast Cancer That Can Be Removed by Surgery
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Niraparib and TSR-042 in Recurrent Endometrial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Cancer
Interventions: DRUG: Niraparib|DRUG: TSR-042
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intracoronary Bolus Only Compared With Intravenous Bolus and 12-hours Infusion of Abciximab in Non-ST Elevation Myocardial Infarction.
Status: UNKNOWN
Conditions: Myocardial Infarction|Angioplasty
Interventions: DRUG: glycoprotein IIb/IIIa inhibitor (abciximab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Seal Pressure With Classical Laryngeal Mask and Cookgas Mask in Adult Patients
Status: UNKNOWN
Conditions: Seal Pressure
Interventions: DEVICE: cookgas mask|DEVICE: LMA mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: rTMS for Treatment of Pain and Craving
Status: COMPLETED
Conditions: Pain, Chronic|Pain Acute
Interventions: DEVICE: Real Transcranial Magnetic Stimulation|DEVICE: Sham Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Validation Study of MR Lymphangiography Using SPIO, a New Lymphotropic Superparamagnetic Nanoparticle Contrast
Status: TERMINATED
Conditions: Bladder Cancer|Genitourinary Cancer|Prostate Cancer
Interventions: DRUG: Ferumoxtran-10 (USPIO)|PROCEDURE: MR lymphangiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Indices of Stimulant Treatment in Drug-Naive Youth at Risk for Substance Use Disorder
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity|Conduct Disorder|Substance Abuse
Interventions: DRUG: Adderall
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Perioperative Chemotherapy in Gastric Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Docetaxel|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: Fluorouracil|DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT