pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Time Based Strategy to Reduce Clopidogrel Associated Bleeding Related to Coronary Artery Bypass Graft (CABG)
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: OTHER: Clopidogrel withdraw prior to CABG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Increasing Plasma Adrenaline Levels Through Breathing Techniques - an Explorative Study
Status: COMPLETED
Conditions: Autoimmune Diseases
Interventions: BEHAVIORAL: Hyper/hypoventilation|BEHAVIORAL: Strength ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Combination Treatment With an HCV Polymerase Inhibitor (RO5024048) and an HCV Protease Inhibitor (RO5190591/Danoprevir) in Genotype 1 Chronic Hepatitis C Patients
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: RO5024048|DRUG: danoprevir|DRUG: danoprevir|DRUG: danoprevir|DRUG: danoprevir|DRUG: danoprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pioglitazone Therapy Targeting Fatigue in Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Muscle Fatigue
Interventions: DRUG: Pioglitazone 15mg|DRUG: Pioglitazone 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind, Placebo Controlled Study of Intravenous Immunoglobulin for HIV-Associated Myelopathy
Status: TERMINATED
Conditions: HIV-associated Myelopathy
Interventions: DRUG: Intravenous Immunoglobulin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glucarpidase Effect on Severe Delayed HDM-clearance in Children Treated With High-dose Mtx in ALL
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia (ALL)
Interventions: DRUG: Glucarpidase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Isotretinoin In Preventing Recurrences In Chronic Recurrent Dermatophytosis
Status: UNKNOWN
Conditions: Tinea
Interventions: DRUG: Isotretinoin|DRUG: Terbinafine|DRUG: Itraconazole 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Project Self in Improving Cervical Cancer Screening Rates in Hispanic and African American Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Subject
Interventions: OTHER: Educational Intervention|PROCEDURE: HPV Self-Collection|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Hepatocellular Carcinoma Study Comparing Vaccinia Virus Based Immunotherapy Plus Sorafenib vs Sorafenib Alone
Status: COMPLETED
Conditions: Hepatocellular Carcinoma (HCC)
Interventions: BIOLOGICAL: Pexastimogene Devacirepvec (Pexa Vec)|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Platelet-rich Fibrin and Platelet Rich Plasma in Female Pattern Hair Loss Patients
Status: RECRUITING
Conditions: Female Pattern Hair Loss|Platelet-Rich Plasma|Platelet-rich Fibrin
Interventions: DEVICE: Platelet rich plasma|DEVICE: Platelet rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy of Duloxetine in Outpatients With Major Depressive Disorder and Pain
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Anti-OX40 Antibody in Head and Neck Cancer Patients
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Anti-OX40 antibody administration|PROCEDURE: Surgical Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Absorption, Metabolism, and Excretion of [14C]-Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) Following a Single Oral Dose in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TBPM-PI-HBr
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study to Reduce Calcineurininhibitor Toxicity in Pediatric and Adolescent Kidney Transplant Recipients
Status: TERMINATED
Conditions: Kidney Transplant
Interventions: DRUG: Reduction of cyclosporine A (CSA)-dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Topical Cysteamine in Nephropathic Cyctinosis
Status: COMPLETED
Conditions: Nephropathic Cyctinosis|Corneal Cystine Crystals
Interventions: DRUG: Cysteamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: P3 Study to Assess Efficacy and Safety of Cefepime/Nacubactam and Aztreonam/Nacubactam Versus Best Available Therapy for Adults With Infection Due to Carbapenem Resistant Enterobacterales
Status: RECRUITING
Conditions: Complicated Urinary Tract Infection|Acute Pyelonephritis|Hospital-acquired Bacterial Pneumonia|Ventilator-associated Bacterial Pneumonia|Complicated Intra-abdominal Infection
Interventions: DRUG: co-administration of cefepime and nacubactam|DRUG: co-administration of aztreonam and nacubactam|DRUG: BAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Occlusal Splint and Therapeutic Home Exercises
Status: COMPLETED
Conditions: Quality of Life|Neuropathic Pain|Somatic Pain
Interventions: OTHER: Mandibular oral occlusal splint|OTHER: Temporomandibular joint Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feedback Reports and e-Learning in Primary Care Spirometry
Status: COMPLETED
Conditions: Respiratory Tract Diseases|Pulmonary Disease, Chronic Obstructive|Asthma
Interventions: OTHER: e-learning & performance feedback|OTHER: usual practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effect of Aerobic Exercises on Trace Elements in Post-menopausal Women After Radiotherapy
Status: RECRUITING
Conditions: Trace Elements Levels After Breast Cancer Radiotherapy
Interventions: OTHER: Aerobic Exercise three time a week
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effectivity and Safety of BIOSCAFF®H Compared to DuraGen®, in Patients Undergoing Dural Repair
Status: NOT_YET_RECRUITING
Conditions: Cerebrospinal Fluid Leakage
Interventions: DEVICE: Human collagen matrix graft|DEVICE: Bovine collagen matrix graft
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Association of Anthropometrics With Grip Strength and Smash Quality Post Six Week Elastic Resistance Training
Status: COMPLETED
Conditions: Anthropometric Measurements and Elastic Resistance Training|Sports Physical Therapy
Interventions: OTHER: Elastic resistance training|OTHER: Conventional Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bidirectional Tuning of the AFO Stiffness
Status: RECRUITING
Conditions: Neuromuscular Disorders
Interventions: DEVICE: NEURO SWING AFO (Fior& Gentz, Lüneburg In Duderstadt, Germany)|DEVICE: WalkOn Reaction® (Ottobock, Duderstadt)|DEVICE: Matrix Max2® (TruLife, Dublin, Ireland)|DEVICE: Matrix® (TruLife, Dublin, Ireland)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Suprascapular Nerve Block Versus ISB Block in Arthroscopic Shoulder Surgery
Status: COMPLETED
Conditions: Shoulder Surgery
Interventions: PROCEDURE: interscalene block group|PROCEDURE: Suprascapular nerve block group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Beta-blockers for Oesophageal Varices
Status: RECRUITING
Conditions: Cirrhoses, Liver|Oesophageal Varices
Interventions: DRUG: Carvedilol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy Of Bupropion For Attention Deficit Hyperactivity Disorder (ADHD) In Adults
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)|Substance Use Disorder (SUD)
Interventions: DRUG: Bupropion SR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Operative Treatment of Ankle Fractures
Status: COMPLETED
Conditions: Ankle Fracture, Trimalleolar|Ankle Fracture - Lateral Malleolus|Ankle Fracture, Bimalleolar
Interventions: DIAGNOSTIC_TEST: Specific provocation test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mechanisms of N-acetylcysteine Mediated Vascular Adverse Effects
Status: COMPLETED
Conditions: Poisoning
Interventions: DRUG: Chlorphenamine and Ranitidine|DRUG: Paracetamol|DRUG: Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Caudal Blockade and Dorsal Penile Nerve Block With and Without the Intravenous Administration of Dexamethasone for Analgesia After Paediatric Male Circumcision
Status: RECRUITING
Conditions: Analgesic Effect
Interventions: DRUG: Dexamethasone|PROCEDURE: Caudale Blockade with levobupivacaine|PROCEDURE: Dorsal penile nerve block with levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: This Study Will Evaluate the Efficacy and Safety of LCZ696 Compared to Enalapril on Morbidity and Mortality of Patients With Chronic Heart Failure
Status: TERMINATED
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: DRUG: LCZ696 200 mg BID|DRUG: Enalapril 10 mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Buccal Acupuncture for Delirium Treatment in Older Patients Recovering From Orthopedic Surgery
Status: UNKNOWN
Conditions: Older Patients|Orthopedic Surgery|Postoperative Delirium|Acupuncture|Treatment
Interventions: PROCEDURE: Buccal acupuncture in addition to routine care|OTHER: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between Blood Glucose and Satiety Ratings
Status: UNKNOWN
Conditions: Satiety|Appetite
Interventions: DIETARY_SUPPLEMENT: Generation UCAN supplementation|DIETARY_SUPPLEMENT: Mirexus PhytoSpherix supplementation|BEHAVIORAL: satiety ratings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Repeat Dose Steroid to Prevent Pain Relapse After Total Knee Arthroplasty in Patients With High Pain Response
Status: COMPLETED
Conditions: Post Operative Pain, Acute
Interventions: DRUG: Dexamethasone 24 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Food on Gut Microbiome Composition - a Clinical Trial Determining the Influence of Diet in Gut Microbiome Colonisation and Host Health
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: OTHER: Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Alpha Radiation Emitters Device for the Treatment of of Malignant Cutaneous Tumors
Status: RECRUITING
Conditions: Skin Cancer|Cutaneous Tumor|Cutaneous Metastasis
Interventions: DEVICE: DaRT- Diffusing Alpha-emitters Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avelumab Plus 2nd-generation ADT in African American Subjects With mCRPC
Status: TERMINATED
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Avelumab|DRUG: 2nd generation ADT (abiraterone or enzalutamide)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation on Neural and Behavioral Facets of Social Cognition in Autism Spectrum Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Transcranial Magnetic Stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Op Quality of Life After Colorectal Surgery
Status: COMPLETED
Conditions: Colorectal Neoplasms|Colitis, Ulcerative|Diverticulitis|Colonic Polyps|Crohn Disease
Interventions: PROCEDURE: Laparoscopic or open colorectal surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness Study of MIST Therapy After Cosmetic Surgery Procedures of the Face and Body
Status: COMPLETED
Conditions: Cosmetic Surgery
Interventions: DEVICE: MIST Therapy|OTHER: Standard Postoperative Incision Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Outcomes With Near-Complete Estrogen Deprivation
Status: RECRUITING
Conditions: Breast Cancer|Triple Negative Breast Cancer|Cardiovascular Complications
Interventions: DRUG: Adenosine Stress Cardiac Magnetic Resonance Imaging|DIAGNOSTIC_TEST: Electrocardiogram|DIAGNOSTIC_TEST: Computed Tomography Angiogram|OTHER: Laboratory Testing|BEHAVIORAL: Quality of Life Survey
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial With Cetuximab in Maintenance Therapy After Platinum Based Chemotherapy in First Line Treatment of Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Cetuximab plus Platinum-based Doublet Chemotherapy|DRUG: Cetuximab 500 mg/m^2|DRUG: Cetuximab 250 mg/m^2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of GQ1010 in Subjects With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Malignant Solid Tumors
Interventions: DRUG: Dose Escalation|DRUG: Dose Expansion1|DRUG: Dose Expansion2|DRUG: phase II
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Transversus Abdominis Plane Block for Gynecologic Surgery (GYNTAP)
Status: WITHDRAWN
Conditions: Postoperative Pain|Postoperative Nausea and Vomiting
Interventions: DRUG: Ropivacaine|OTHER: Placebo|PROCEDURE: Transversus Abdominis Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Salvage of Myocardial Infarction Documented by MRI in Patients Undergoing Rescue Percutaneous Coronary Intervention
Status: UNKNOWN
Conditions: Myocardial Infarction|Myocardial Ischemia
Interventions: DEVICE: Cardiac Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of an Intra Uterine Balloon to Prevent Recurrent Adhesions (REpAIR)
Status: COMPLETED
Conditions: Adhesion; Uterus, Internal
Interventions: DEVICE: intra uterine Cook balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Prazosin for Treatment of Patients With Alcohol Dependence (AD) and Post Traumatic Stress Disorder (PTSD).
Status: COMPLETED
Conditions: Alcohol Dependence|Stress Disorders, Post-Traumatic
Interventions: DRUG: Prazosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fibre and Appetite Regulation Trial (FART)
Status: COMPLETED
Conditions: Obesity|Diabetes
Interventions: DRUG: Low fibre breakfast cereal (puffed rice/cornflakes)|DRUG: High fibre cereal (All Bran/Bran Flakes)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Study of Bevacizumab With Different Manufacturing Process in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Male Subjects
Interventions: DRUG: bevacizumab with new manufacturing process.|DRUG: bevacizumab with old manufacturing process.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Open-Label Study To Evaluate MN-001 on HDL & Triglyceride in NASH & NAFLD Subjects
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis|Hypertriglyceridemia|Non-alcoholic Fatty Liver Disease|Hypercholesterolemia
Interventions: DRUG: MN-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Colchicine Prevents Myocardial Injury After Non-Cardiac Surgery Pilot Study
Status: WITHDRAWN
Conditions: Myocardial Infarction|Myocardial Injury|Major Adverse Cardiac Events|Infectious Complications
Interventions: DRUG: Colchicine 0.6 mg|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Standard of Care Versus Urine Testing With Selective PHarmacogenomics for Effective Drug and Dosing REgimens
Status: UNKNOWN
Conditions: Target Drug-related Adverse Events
Interventions: OTHER: Urine diagnostic testing as SOC, drug regimen changes per SOC|OTHER: Urine diagnostic testing with selective PGx testing, drug regimen changes based on PGx test results
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Probiotics on Gut Microbiotain After Helicobacter Pylori Eradication
Status: NOT_YET_RECRUITING
Conditions: Helicobacter Pylori Infection|Infections|Intestinal Bacteria Flora Disturbance
Interventions: DRUG: Vonoprazan|DRUG: Amoxicillin|DRUG: probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-interventional Local Study on Prescription Behavior of Anticoagulation Therapy in Secondary Stroke Prevention in Atrial Fibrillation Patients
Status: COMPLETED
Conditions: Stroke|Embolism
Interventions: OTHER: Rivaroxaban ( Xarelto, BAY59-7939)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sign Here: How to Conduct Informed Consent With Deaf Individuals
Status: COMPLETED
Conditions: Cultural Competency
Interventions: OTHER: "Sign Here" training intervention|OTHER: Intervention as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Collaborative H1N1 Adjuvant Treatment Pilot Trial
Status: TERMINATED
Conditions: Critically Ill|H1N1/Influenza Infection
Interventions: DRUG: Rosuvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Versus Subcutaneous Administration of Low Molecular Weight Heparin for Thromboprophylaxis in Critically Ill Patients
Status: COMPLETED
Conditions: Critical Illness
Interventions: DRUG: Nadroparin (intravenous Infusion)|DRUG: Nadroparin (subcutaneous group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Ivermectin and Doxycycline in Treatment of Covid-19
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: Ivermectin and Doxycycline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of ADL5945 Once Daily for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Placebo|DRUG: ADL5945 0.25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Bivalirudin for Anticoagulation in Patients With Extracorporeal Membrane Oxygenation
Status: NOT_YET_RECRUITING
Conditions: Extracorporeal Membrane Oxygenation Complication
Interventions: DRUG: bivalirudin|DRUG: unfractionated heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: First-Line Treatment Induced With mFOLFOX6 and HLX04 Regimen, Following Combined With Serplulimab in MSS Initially Unresectable Metastatic Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Efficacy, Self|Safety Issues|Colo-rectal Cancer
Interventions: DRUG: mfolfox6 and hlx04 regimen and Serplulimab|DRUG: mfolfox6 and hlx04 regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Cardiac Rehabilitation Through Behavioral Nudges
Status: UNKNOWN
Conditions: Acute Myocardial Infarction|Percutaneous Coronary Intervention|Coronary Artery Disease|Valvular Disease|Chronic Stable Angina|Chronic Stable Heart Failure
Interventions: OTHER: Hospital-based CR + Movn Application|OTHER: Choice of Hospital or home-based CR + Movn Application|OTHER: Hospital-based CR + Movn Application + Nudge|OTHER: Choice of Hospital or home-based CR + Movn Application + Nudge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Role of Manual Twirling Acupuncture in Reducing Muscle Pain and Stiffness After Biceps Curling in Healthy Untrained Individuals
Status: COMPLETED
Conditions: Muscle Soreness|Stiffness of Elbow, Not Elsewhere Classified
Interventions: PROCEDURE: Manual Acupuncture Twirling,|PROCEDURE: Manual Acupuncture Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rosiglitazone-Metformin Combination Versus Metformin-Sulfonylurea Combination On Beta-Cell Function In Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: rosiglitazone-metformin|DRUG: Metformin|DRUG: metformin+ gliclazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of ADHD Medication (TEAM) Study
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: OROS-Methylphenidate (MPH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Virtual Reality on Caregivers of Palliative Care Patients
Status: NOT_YET_RECRUITING
Conditions: Mental Well-being|Quality of Life
Interventions: OTHER: Virtual reality intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sunitinib in Treating Patients With Newly Diagnosed Stage II or Stage III Breast Cancer That Can Be Removed by Surgery
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: sunitinib malate|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: needle biopsy|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Randomized Trial Assessing Pain Efficacy With Radium-223 in Symptomatic Metastatic Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Prostate Cancer|Pain
Interventions: DRUG: Radium-223
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing Immunogenicity and Safety of Different Formulations of HBV-MPL Vaccine With Engerix™-B in Adults Aged 18-40 y
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: HBV-MPL vaccine|BIOLOGICAL: Engerix™-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Terlipressin, Somatostatin, and Octreotide for Control of Variceal Bleeding
Status: COMPLETED
Conditions: Variceal Bleeding, Cirrhosis
Interventions: DRUG: Terlipressin|DRUG: Somatostatin|DRUG: Octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Intensity Transplant in Medically Refractory Systemic Lupus Erythematosus (SLE) and Systemic Sclerosis (SSc)
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus|Systemic Sclerosis
Interventions: PROCEDURE: Reduced Intensity Allogeneic Transplant|DRUG: Fludarabine|DRUG: Busulfan|DRUG: Campath
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Pharmacokinetics and Pharmacodynamics of Huperzine A Injection in Healthy Chinese Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Subjects
Interventions: DRUG: Huperzine A injection|DRUG: Huperzine A injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Dyspepsia: Validation of a Questionnaire for Symptom Assessment in FD PDS Subgroup
Status: COMPLETED
Conditions: Functional Dyspepsia|Postprandial Fullness Syndrome
Interventions: DRUG: Itopride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Empowering Latinas to Obtain Guideline Concordant Screenings
Status: RECRUITING
Conditions: Breast Cancer Screening
Interventions: OTHER: Educate|OTHER: Empower
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Study of ISIS 703802 in Participants With Hypertriglyceridemia, Type 2 Diabetes Mellitus, and Nonalcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: NAFLD|Diabetes Mellitus, Type 2|Hypertriglyceridemia|Fatty Liver, Nonalcoholic
Interventions: DRUG: Placebo|DRUG: ISIS 703802 40 mg|DRUG: ISIS 703802 80 mg|DRUG: ISIS 703802 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROSTVAC in Combination With Nivolumab in Men With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: PROSTVAC-V/F|DRUG: Nivolumab|PROCEDURE: Prostatectomy|PROCEDURE: Biopsy|DRUG: Tylenol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Seasonal Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine in Children in Mali
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Seasonal IPT in children - Sulfadoxine-pyrimethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Learn About The Study Medicine (PF-07038124) In Patients With Mild To Moderate Atopic Dermatitis Or Mild To Severe Plaque Psoriasis.
Status: COMPLETED
Conditions: Atopic Dermatitis|Plaque Psoriasis
Interventions: DRUG: PF-07038124 ointment 0.01%|DRUG: Vehicle ointment|DRUG: PF-07038124 ointment 0.03%|DRUG: PF-07038124 ointment 0.06%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Multivessel Minimally Invasive Coronary Artery Bypass Graft Surgery
Status: UNKNOWN
Conditions: Ischemic Heart Disease
Interventions: PROCEDURE: minimal invasive coronary artery bypass graft surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-CD7 CAR-T Cell Therapy for Relapse and Refractory CD7 Positive T Cell Malignancies
Status: RECRUITING
Conditions: T Lymphoblastic Leukemia/Lymphoma|T-cell Acute Lymphoblastic Leukemia|Peripheral T Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Anaplastic Large Cell Lymphoma
Interventions: DRUG: anti-CD7 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypothermia in Acute Stroke With Thrombolysis Imaging Evaluation of Revascularization
Status: TERMINATED
Conditions: Acute Ischemic Stroke
Interventions: OTHER: IV t-PA and normothermia|DEVICE: IV-tPA and hypothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy, Safety, and Pharmacokinetic Study of Prophylactic Emicizumab Versus No Prophylaxis in Hemophilia A Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemophilia A
Interventions: DRUG: Emicizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Violet Device Dosed Ultra Violet-C Light (UV-C) Exposure on Healthy Hand Skin
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Volunteers
Interventions: DEVICE: Ultraviolet Light (UV-B)|DEVICE: Ultraviolet lights (UV-C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Approaches to Stop Hypertension for Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Diabetes|Diabetes type2|Type2 Diabetes|Type 2 Diabetes|Type II Diabetes|Hypertension|High Blood Pressure
Interventions: OTHER: DASH4D diet|OTHER: comparison diet|OTHER: higher sodium|OTHER: lower sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of VB-111 With Paclitaxel vs Paclitaxel for Treatment of Recurrent Platinum-Resistant Ovarian Cancer (OVAL)
Status: COMPLETED
Conditions: Recurrent Platinum Resistant Ovarian Cancer
Interventions: DRUG: VB-111 + Paclitaxel|DRUG: Placebo + Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Image and Performance Diagnoses of the 3D Sequence of Cholangio-pancreatography MRI in Apnea With Compressed Acquisition
Status: ACTIVE_NOT_RECRUITING
Conditions: Cholangiopancreatography
Interventions: DIAGNOSTIC_TEST: CS plus FRFSE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Low-dose Radiation and Contrast Agent Exposure Protocol for Coronary CTA in Diabetic Patients
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: OTHER: double-low scanning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety Study of Inhaled CVT 301 in Parkinson's Disease Patients for Treatment of OFF Episodes
Status: COMPLETED
Conditions: Idiopathic Parkinson's Disease
Interventions: DRUG: CVT-301|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of SGN-30 (Anti-CD30 mAb) in Patients With Primary Cutaneous Anaplastic Large Cell Lymphoma
Status: COMPLETED
Conditions: Large Cell Lymphoma
Interventions: DRUG: SGN-30
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Effects of GH and IGF-I in Growth Hormone Deficient(GHD) and Diabetes and Impaired Glucose Tolerance(IGT)
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: NutropinAq (GH) and Increlex (IGF-I)|DRUG: NutropinAq and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Potential of Technology to Improve Chronic Disease Management and Quality of Care
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: BEHAVIORAL: Patient diabetic self-management using the diabetic patient portal tools|BEHAVIORAL: A variety of educational interventions for non-adopters of the technology, and for non-compliant patients.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lacosamide in Neonatal Status Epilepticus
Status: UNKNOWN
Conditions: Epilepsy
Interventions: DRUG: Lacosamide|DRUG: Phenobarbital
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Tezepelumab in Adults With Chronic Spontaneous Urticaria
Status: COMPLETED
Conditions: Chronic Spontaneous Urticaria
Interventions: BIOLOGICAL: Tezepelumab Dose 1|BIOLOGICAL: Tezepelumab Dose 2|BIOLOGICAL: Omalizumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Impacts of Oral Gastrografin Follow Through in Adhesive Small Bowel Obstruction (SBO)
Status: COMPLETED
Conditions: Small Bowel Obstruction
Interventions: OTHER: Oral Gastrografin|OTHER: Nothing per os
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of GT300 in Healthy Subjects
Status: UNKNOWN
Conditions: Lewy Body Disease
Interventions: DRUG: GT300|DRUG: Microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gene Therapy of Pancreatic Ductal Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma
Interventions: GENETIC: Gene Therapy product CYL-02 = plasmid DNA pre-complexed to linear polyethylenimine encoding sst2 + dck::umk genes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of TAK-583 in Subjects With Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathies
Interventions: DRUG: TAK-583|DRUG: TAK-583|DRUG: TAK-583|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Neurokinin-1 Receptor (NK1R) Antagonism on Pruritus in Patients With Sezary Syndrome
Status: TERMINATED
Conditions: Sezary Syndrome|Pruritus
Interventions: DRUG: Aprepitant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Performance of the Organ Recovery Systems LifePort® Liver Transporter System, a Machine Perfusion System, for Liver Transplant
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DEVICE: Hypothermic machine perfusion|DEVICE: Static cold storage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Japanese BAY88-8223 Monotherapy Phase II Study
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Radium-223 dichloride (Xofigo, BAY88-8223)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Evaluation of Effectiveness of an Internet-based Brief Intervention for Alcohol Use Among Brazilian College Students
Status: COMPLETED
Conditions: Alcohol Drinking
Interventions: BEHAVIORAL: Consequences List Feedback|BEHAVIORAL: Personalized Normative Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Monocentric Study Evaluating Pupillometry as an Objective Measurement for CI Fittings
Status: TERMINATED
Conditions: Hearing Loss, Sensorineural|Hearing Loss, Bilateral|Cochlear Hearing Loss|Hearing Loss, Cochlear
Interventions: OTHER: Pupillometry (Eve-tracking measurements)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cost-effectiveness Analysis Between Two Anticoagulation Strategies for Atrial Fibrillation in the Postoperative Period of Coronary Artery Bypass Graft Surgery
Status: UNKNOWN
Conditions: Atrial Fibrillation New Onset
Interventions: DRUG: Rivaroxaban 20 MG Oral Tablet|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine, 5-Fluorouracil, and Radiation Therapy in the Treatment of Non-Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine|DRUG: 5-Fluorouracil|PROCEDURE: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Video Chat Intervention for Enhancing Self-efficacy for Lifestyle Physical Activity
Status: COMPLETED
Conditions: Physical Activity|Self Efficacy|Working Adults
Interventions: BEHAVIORAL: Efficacy for Lifestyle PA|BEHAVIORAL: Efficacy for Work-life Balance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Action Observation Theraphy in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Live movement observation (Upper Limbs)|BEHAVIORAL: Video Observation (Upper Limbs)|BEHAVIORAL: Live Movement Observation (Lowe Limbs)|BEHAVIORAL: Video Observation (Lower Limbs)|BEHAVIORAL: Static Picture Observation and Upper Limbs Exercise|BEHAVIORAL: Static Picture Observation and Lower Limbs Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Acapella and ELTGOL Technique to Promote Airway Clearance in COPD:a Comparative Study
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Acapella|OTHER: ELTGOL|OTHER: conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and the Tolerability of the Sequential Application of Two Marketed Products in Patients With Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: marketed topical retinoid|DRUG: marketed topical NSAID|DRUG: vehicle gel|DRUG: marketed topical retinoid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomized Study Evaluating the Recurrence Rate of Chronic Subdural Hematoma After Placing a Subperiosteal Drainage Compared to a Subdural Drainage
Status: COMPLETED
Conditions: Chronic Subdural Hematoma
Interventions: PROCEDURE: Subdural Drainage|PROCEDURE: Subperiosteal Drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-dose Ticagrelor in Chinese ACS Patients Undergoing PCI
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: half-dose ticagrelor|DRUG: standard-dose ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The PRECISION Trial (Profiling Early Breast Cancer for Radiotherapy Omission): A Phase II Study of Breast-Conserving Surgery Without Adjuvant Radiotherapy for Favorable-Risk Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer Radiation
Interventions: DEVICE: Prosigna
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Pharmacodynamics of RM-131 in Patients With Diabetic Gastroparesis
Status: COMPLETED
Conditions: Diabetes Mellitus Type 1 and 2|Diabetes Mellitus Complications|Gastroparesis|Gastrointestinal Motility Disorder
Interventions: DRUG: RM-131|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation Between the Effectiveness of Vibration Assisted Syringe and Conventional Syringe
Status: UNKNOWN
Conditions: Anxiety, Dental
Interventions: DEVICE: vibraject
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: StomaphyX Versus Sham for Revisional Surgery in Post-Roux-en-Y Patients to Reduce Regained Weight
Status: TERMINATED
Conditions: Obesity
Interventions: DEVICE: StomaphyX|PROCEDURE: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Skin-to-skin Contact Time and Maternal Psychology
Status: COMPLETED
Conditions: Skin to Skin Contact
Interventions: OTHER: 5 minutes skin to skin contact|OTHER: 60 minutes skin to skin contact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pyrazoloacridine Followed by Radiation Therapy in Treating Adults With Newly Diagnosed Supratentorial Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: pyrazoloacridine|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Phonophoresis on Trigger Points
Status: NOT_YET_RECRUITING
Conditions: Trigger Point Pain, Myofascial
Interventions: OTHER: US with fastum|OTHER: US with reparil|OTHER: US with plain gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Potential of Kava in Enabling Tobacco Cessation - Its Holistic Effects in Managing Stress and Insomnia Associated With Abstinence
Status: RECRUITING
Conditions: Smoking
Interventions: DRUG: Placebo|DRUG: AB-free kava
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Feasibility 3D Perfusion Ultrasound for Liver Cancer SABR Planning and Response Evaluation
Status: COMPLETED
Conditions: Liver Cancer|Liver Tumor|Hepatocellular Carcinoma|Liver Carcinoma
Interventions: DRUG: perflutren lipid microspheres|DIAGNOSTIC_TEST: 3D ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC