pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Framing Eighteen Coils in Cerebral Aneurysms Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Aneurysm
Interventions: PROCEDURE: Coil Embolization with larger Diameter Coils|PROCEDURE: Coil Embolization with Standard Diameter Coils
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obinutuzumab in cGVHD After Allogeneic Peripheral Blood Stem Cell Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Graft vs. Host Disease
Interventions: DRUG: Obinutuzumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Versus Delayed Treatment With Azathioprine or Rituximab in Anti-MOG Antibodies Associated Acute Demyelinating Syndromes in Children: a Randomized Controlled Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Acute Demyelinating Syndrome
Interventions: DRUG: Immediate Azathioprine (1st attack)|DRUG: Immediate Rituximab (1st attack)|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IV Acetaminophen for Acute Post Operative Pain in C-Section Patients
Status: COMPLETED
Conditions: Post-operative Pain
Interventions: DRUG: IV Acetaminophen|OTHER: Saline as placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erlotinib Hydrochloride in Treating Patients With Bladder Cancer Undergoing Surgery
Status: TERMINATED
Conditions: Bladder Carcinoma|Recurrent Bladder Carcinoma
Interventions: DRUG: Erlotinib Hydrochloride|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|OTHER: Placebo|OTHER: Quality-of-Life Assessment|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of DiaPep277 in Newly Diagnosed Type 1 Diabetes Adults
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: DiaPep277|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Polyglutamate Paclitaxel Compared With Docetaxel in Treating Patients With Progressive Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: docetaxel|DRUG: paclitaxel poliglumex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABCB1/P-glycoprotein Expression as Biologic Stratification Factor for Patients With Non Metastatic Osteosarcoma
Status: COMPLETED
Conditions: Osteosarcoma
Interventions: DRUG: Mifamurtide arm|OTHER: 3 drugs arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Etanercept (Enbrel®) for the Treatment of Discoid Lupus Erythematosus
Status: UNKNOWN
Conditions: Discoid Lupus Erythematosus (DLE)
Interventions: DRUG: etanercept(Enbrel®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial Resistance in Acute Cholangitis
Status: RECRUITING
Conditions: Cholangitis Acute|Biliary Tract Diseases|Jaundice; Malignant|Jaundice, Obstructive|Choledocholithiasis
Interventions: PROCEDURE: ERCP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Post-trial Follow-up of MERINO Participants to Evaluate Long-term Effects of Methotrexate Treatment in Adults With Erosive Hand OA.
Status: NOT_YET_RECRUITING
Conditions: Hand Osteoarthritis|Erosive Osteoarthritis
Interventions: DRUG: Methotrexate|OTHER: No treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Does Omega-3 Fatty Acid Supplementation in Pregnancy and During Lactation Protect the Child From Allergic Disease?
Status: UNKNOWN
Conditions: Allergies
Interventions: DIETARY_SUPPLEMENT: Omega-3 long chain polyunsaturated fatty acids|DIETARY_SUPPLEMENT: Soybean oil (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase Ib / Regorafenib With Conventional Chemotherapy/Newly Diagnosed Patients/ Multimetastatic Ewing Sarcoma
Status: RECRUITING
Conditions: Bone Cancer
Interventions: DRUG: regorafenib tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ability of Four Toothpastes to Remove Plaque
Status: COMPLETED
Conditions: Dental Plaque
Interventions: OTHER: 67% Sodium Bicarbonate with 6 herbs plus 923parts per million (ppm) Sodium Fluoride|OTHER: 67% Sodium Bicarbonate without herbs plus 923 ppm Sodium Fluoride|OTHER: 62% Sodium Bicarbonate with 6 herbs and 5% w/w silica plus 923 ppm Sodium|OTHER: 0% Sodium Bicarbonate without herbs plus 923ppm Sodium Fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quasi-Randomized Evaluation of the UCLA Next Day Clinic (NDC)
Status: RECRUITING
Conditions: Pneumonia|Syncope|Congestive Heart Failure|Cellulitis|Pyelonephritis|AKI - Acute Kidney Injury|Diabetic Foot Infection|Osteomyelitis
Interventions: OTHER: Next Day Clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Acute Alcohol Response In Bipolar Disorder: a fMRI Study
Status: COMPLETED
Conditions: Bipolar Disorder|Alcohol Drinking|Alcohol Use Disorder
Interventions: OTHER: alcohol beverage|OTHER: Placebo beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Management of Postoperative Pain Following Total Knee Arthroplasty by Using Acupuncture-moxibustion Therapy
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: acupuncture-moxibustion therapy|PROCEDURE: Regular therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Cost Effectiveness of Different Dressing Materials in Diabetic Foot Ulcers
Status: WITHDRAWN
Conditions: Diabetic Foot Ulcers
Interventions: PROCEDURE: Normal Saline|PROCEDURE: Biatin Ag (Foam)|PROCEDURE: Hydrocolloid|PROCEDURE: Hydrogel|PROCEDURE: Ceredak
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Asymptomatic Bacteriuria, Urinalysis Abnormality at the Initiation of SGLT2 Inhibitors and UTI Risk
Status: UNKNOWN
Conditions: Type2diabetes, SGLT2 Inhibitor, Urinary Tract Infection
Interventions: DIAGNOSTIC_TEST: urine culture and urinalysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Concord Grape Juice Alone on Glycemia, Appetite and Cognitive Function in Healthy Adults
Status: COMPLETED
Conditions: Glycemic Response|Appetitive Behavior
Interventions: OTHER: Concord Grape Juice|OTHER: Low flavoniod low essence beverage|OTHER: Low flavonoid beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Laser Lithotripsy for Ureteral Stones
Status: COMPLETED
Conditions: Ureteric Stone
Interventions: PROCEDURE: Retrograde and Antegrade Ureteroscopic Laser Lithotripsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of Docetaxel and Carboplatin in Metastatic Malignant Melanoma Failed First-Line Dacabazine or Temozolomide Contained Therapy
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DRUG: docetaxel 35mg/m2|DRUG: Carboplatin AUC3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Oral Dehydroepiandrosterone as a Concomitant Therapy to Oral Contraceptives in Women Complaining of Reduced Libido
Status: COMPLETED
Conditions: Libido
Interventions: DRUG: Dehydroepiandrosterone, BAY86-5314|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Pilates Exercises On Posture In Patients With Shoulder-Neck Posture Problem
Status: COMPLETED
Conditions: Posture|Exercise
Interventions: OTHER: Clinical Pilates Exercises|OTHER: Classic Posture exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LC Bead Embolization Agent With Doxorubicin in the Treatment Liver Metastasis From Melanoma
Status: COMPLETED
Conditions: Stage IV Melanoma
Interventions: DEVICE: LC beads loaded with Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health Education Intervention in Reducing Weight Gain in Patients With Newly Diagnosed Stage I-IV Breast Cancer Undergoing Chemotherapy
Status: COMPLETED
Conditions: Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer
Interventions: OTHER: educational intervention|OTHER: counseling intervention|BEHAVIORAL: telephone-based intervention|OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: the Efficiency of Thalidomide for Recurrent Small Intestinal Bleeding Due to Gastrointestinal Vascular Malformation
Status: COMPLETED
Conditions: Gastrointestinal Vascular Malformation
Interventions: DRUG: Thalidomide (100mg)|DRUG: Thalidomide (50mg)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Different Preventive Regimens in Cariogram Parameters and DMF Scores of High Caries Risk Patients: A Randomized Control Trial
Status: UNKNOWN
Conditions: Prevention of Dental Caries
Interventions: OTHER: Fluoride toothpaste|OTHER: fluoride toothpaste and chlorhexidine mouthwash|OTHER: fluoride toothpaste, chlorhexidine mouthwash, MI varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Short Bowel Syndrome and Teduglutide Versus Placebo
Status: COMPLETED
Conditions: Short Bowel Syndrome
Interventions: DRUG: Teduglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Base Edited CAR7 T Cells to Treat T Cell Malignancies (TvT CAR7)
Status: RECRUITING
Conditions: Relapsed/Refractory T-cell Acute Lymphoid Leukaemia
Interventions: BIOLOGICAL: Cryopreserved BE CAR7 T cells (BE752TBCCLCAR7PBL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Irinotecan and Temozolomide in Treating Young Patients With Recurrent Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: irinotecan hydrochloride|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Faecal Microbiota Transplantation After Allogeneic Stem Cell Transplantation
Status: RECRUITING
Conditions: Acute Leukemia in Remission|Myelodysplastic Syndromes|Myeloproliferative Syndrome|Hodgkin Lymphoma|Lymphoma, Non-Hodgkin|Myeloma|Chronic Lymphocytic Leukemia
Interventions: DRUG: Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Empagliflozin in NODAT
Status: TERMINATED
Conditions: New Onset Diabetes After Transplant|Kidney Transplant; Complications
Interventions: DRUG: Empagliflozin|DRUG: Linagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lyophilized Fecal Microbiome Transfer vs. Vancomycin Monotherapy for Primary Clostridioides Difficile Infection
Status: RECRUITING
Conditions: Clostridioides Difficile Infection
Interventions: COMBINATION_PRODUCT: Lyophilized fecal microbiome transfer|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Healthy School mEAls With Less Salt：an Action to Reduce Salt Intake in School Meals for Children in Rural China
Status: NOT_YET_RECRUITING
Conditions: Blood Pressure
Interventions: OTHER: Main study intervention-Salt substitute|OTHER: Main study control-Usual salt|OTHER: Ancillary study intervention-Meal trays|OTHER: Ancillary study control-Bowls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of Exoskeleton Type Robotic Gait Training Using CIMT for Lower Extremity: in the Aspect of Gait Independence and Balance
Status: UNKNOWN
Conditions: Acute Hemiplegic Stroke Including Subacute Phases
Interventions: DEVICE: Conventional robot-assisted gait training|DEVICE: Lower CIMT robot-assisted gait training group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Perineural and Systemic Effect of Dexamethasone as an Adjuvant for Prolongation of Four Nerve Blocks With Bupivacaine in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Analgesia|Pain, Postoperative
Interventions: DRUG: Dexamethasone|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Evaluating the Efficacy and Safety of Prophylactic Administration of Concizumab in Haemophilia A and B Patients With Inhibitors
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A With Inhibitors|Haemophilia B With Inhibitors
Interventions: DRUG: Concizumab|DRUG: Eptacog alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of IMG-007 in Adults With Atopic Dermatitis (AD)
Status: TERMINATED
Conditions: Atopic Dermatitis|Moderate-to-severe Atopic Dermatitis|AD
Interventions: DRUG: Placebo|DRUG: IMG-007
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Making Mindfulness Matter© in Children With Epilepsy
Status: COMPLETED
Conditions: Epilepsy in Children|Mindfulness|Quality of Life
Interventions: BEHAVIORAL: Making Mindfulness Matter© (M3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioavailability of Soft Gelatin Capsule Formulation of BI 201335 NA Compared to the Solution Formulation in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: low dose BI 201335 NA soft gelatine capsule (SGC)|DRUG: high dose BI 201335 NA soft gelatine capsule (SGC)|DRUG: low dose BI 201335 NA powder in bottle (PIB)|DRUG: high dose BI 201335 NA powder in bottle (PIB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of RPh201 on Chronic Vegetative State (CVS): fMRI Study
Status: SUSPENDED
Conditions: Chronic Vegetative State
Interventions: DRUG: RPh201|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Changes Following Percutaneous Venoplasty in Multiple Sclerosis Patients
Status: WITHDRAWN
Conditions: Multiple Sclerosis|Chronic Cerebrospinal Venous Insufficiency
Interventions: PROCEDURE: percutaneous venoplasty to alleviate chronic cerebrospinal venous insufficiency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics of JNJ-38518168 in Patients With Mild and Moderate Hepatic Impairment Compared With Patients With Normal Hepatic Function
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: JNJ-38518168
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Investigating a Delayed-Release Pancrelipase in Patients With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Pancrelipase Delayed Release|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vascular Anomaly Pathology and Genomics Biopsy Study
Status: COMPLETED
Conditions: Vascular Malformations|Vascular Anomaly|Hemangioma|Arteriovenous Malformations|Venous Malformation|Klippel Trenaunay Syndrome|Lymphatic Malformation
Interventions: PROCEDURE: Percutaneous Vascular Anomaly/Malformation Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Phytonutrients on Vascular Health and Skin in Obese Males
Status: TERMINATED
Conditions: Erythema|Inflammation
Interventions: OTHER: Pomegranate Juice|OTHER: Placebo Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Strategies of Interruption/Reinitiation of Antiretroviral Therapy in HIV-Infected Patients With Lipodystrophy
Status: COMPLETED
Conditions: HIV-Associated Lipodystrophy Syndrome
Interventions: DRUG: Standard continuous antiretroviral therapy|DRUG: CD-4 guided therapy interruption|DRUG: Viral load driven treatment interruption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BL-8040 and Nelarabine for Relapsed or Refractory T-Acute Lymphoblastic Leukemia/ Lymphoblastic Lymphoma
Status: TERMINATED
Conditions: T-Acute Lymphoblastic Leukemia|Adult T Lymphoblastic Lymphoma
Interventions: DRUG: BL-8040|DRUG: Nelarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Concentrate in Achilles Tendon Repair
Status: COMPLETED
Conditions: Achilles Tendon Rupture|Soft Tissue Injury|Tendon Injury
Interventions: BIOLOGICAL: Autologous platelets|BIOLOGICAL: no injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Registry for Patients With Childhood.Onset Craniopharyngioma, Xanthogranuloma, Cysts of Rathke's Pouch, Meningioma, Pituitary Adenoma, Arachnoid Cysts
Status: RECRUITING
Conditions: Craniopharyngioma|Obesity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mechanically Ventilated Children and Pacifiers
Status: NOT_YET_RECRUITING
Conditions: Mechanical Ventilation Complication|Pneumonia|Bronchiolitis
Interventions: DEVICE: Modified pacifier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Hydroxychloroquine, Vitamin C, Vitamin D, and Zinc for the Prevention of COVID-19 Infection
Status: RECRUITING
Conditions: COVID-19|Coronavirus Infection|Sars-CoV2|Corona Virus Infection|COVID|Coronavirus|Coronavirus-19|Coronavirus 19
Interventions: DRUG: Hydroxychloroquine|DIETARY_SUPPLEMENT: Vitamin C|DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: MAtrix Therapy for Hard-to-heal ChrOnic Wounds
Status: RECRUITING
Conditions: Chronic Ulcer of Leg or Foot|Diabetic Foot Ulcer|Arterial Ulcer|Venous Ulcer of Leg
Interventions: DEVICE: CACIPLIQ20®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Trial of Afatinib Plus Prednisone for Advanced Squamous NSCLC
Status: RECRUITING
Conditions: Advanced Squamous Non Small Cell Lung Cancer
Interventions: DRUG: Afatinib + Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Treatment in Non-Small Cell Lung Cancer After Failure of Epidermal Growth Factor Receptor-tyrosine Kinase Inhibitor
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: sorafenib (Nexavar)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alogliptin Tablets Specified Drug-use Survey "Type 2 Diabetic Patients Receiving Combination Therapy With a Hypoglycemic Agent (e.g., Insulin Preparations or Rapid-acting Insulin Secretagogues)"
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Alogliptin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Cerebral and Cognitive Changes After Intermittent Theta Burst Stimulation (iTBS) Treatment for Depression
Status: RECRUITING
Conditions: Depression, Unipolar|Depression Moderate
Interventions: DEVICE: Intermittent Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aprepitant, Granisetron, & Dexamethasone in Preventing Nausea & Vomiting in Pts. Receiving Cyclophosphamide Before a Stem Cell Transplant
Status: COMPLETED
Conditions: Breast Cancer|Chronic Myeloproliferative Disorders|Gestational Trophoblastic Tumor|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Nausea and Vomiting|Neuroblastoma|Ovarian Cancer|Testicular Germ Cell Tumor
Interventions: DRUG: Aprepitant|DRUG: Cyclophosphamide|DRUG: Dexamethasone|DRUG: Granisetron hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of the Investigational Drug Campath-1H in Preventing Rejection of Transplanted Kidneys
Status: COMPLETED
Conditions: Graft Rejection|Kidney Disease
Interventions: DRUG: Alemtuzumab and DSG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictive Model to Early Diagnosis of Anastomotic Leak After Esophagectomy and Gastrectomy.
Status: UNKNOWN
Conditions: Esophagus Cancer|Gastric Cancer|Leak, Anastomotic|Complication
Interventions: OTHER: audit of complications, prospective data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating an Exercise Program to Reduce Cardiovascular Risk Factors in Children Infected With HIV
Status: COMPLETED
Conditions: HIV|Acquired Immunodeficiency Syndrome|Cardiovascular Diseases
Interventions: BEHAVIORAL: Exercise Program|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Efficacy, Safety of Vandetanib in Patients With Differentiated Thyroid Cancer
Status: COMPLETED
Conditions: Differentiated Thyroid Cancer
Interventions: DRUG: Vandetanib (SAR390530)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glycemic and Insulinemic Response With Different Sources of Soluble Fiber in Patients Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Dietary Modification|Diabetes Mellitus Type 2|Insulin Tolerance|Diabetic Blood Glucose Monitoring
Interventions: OTHER: HFD Meal: High fiber from food|DIETARY_SUPPLEMENT: HFS Meal: High fiber from supplement|OTHER: UF Meal: usual amount of fiber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Maitland's Antero-Posterior Versus Lateral Mobilizations on Cardiovascular Responses
Status: UNKNOWN
Conditions: Neck Pain
Interventions: OTHER: MAITLAND'S ANTEROPOSTERIOR(AP) MOBILIZATION|OTHER: MAITLAND'S LATERAL MOBILIZATION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Connective Graft and Xenogeneic Matrix, in Patients With Multiple Gingival Recessions
Status: COMPLETED
Conditions: Gingival Recession, Generalized
Interventions: PROCEDURE: Root coverage surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Repaglinide and Metformin Combined in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: repaglinide|DRUG: metformin|DRUG: glicazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduction of Pain Symptoms With Stereotactic Radiotherapy on Bone Metastases
Status: UNKNOWN
Conditions: Bone Metastases|Radiotherapy|Technology
Interventions: RADIATION: Simultaneous Integrated Boost-SIB on macroscopic metastases
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Gynevac Lactobacillus Vaccine in the Treatment of Bacterial Vaginosis
Status: UNKNOWN
Conditions: Bacterial Vaginosis
Interventions: BIOLOGICAL: Gynevac|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Regeneration on Larynx Soft Tissue Guided by Functional Collagen Scaffold
Status: COMPLETED
Conditions: Vocal Cord Dysfunction
Interventions: BIOLOGICAL: Autologous fat transplantation|BIOLOGICAL: Functional collagen scaffold transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Liver Transplantation Results in Hepatocellular Carcinoma Patients With Immunosuppression Without Steroids
Status: COMPLETED
Conditions: Immunosuppression|Hepatocellular Carcinoma|Liver Transplantation|Post-operative Complications
Interventions: DRUG: solu medrol|DRUG: a steroid-free immunosuppression protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fixed Versus Flexible Gonadotropin-releasing Hormone (GnRH) Antagonist Initiation
Status: COMPLETED
Conditions: Subfertility
Interventions: DRUG: Cetrorelix (Cetrotide)|DRUG: Cetrorelix (Cetrotide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Efpeglenatide Versus Placebo in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Basal Insulin Alone or in Combination With Oral Antidiabetic Drug(s)
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Efpeglenatide SAR439977|DRUG: Placebo|DRUG: Background therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Project to Improve Symptoms and Mood in People With Spinal Cord Injury
Status: COMPLETED
Conditions: Major Depressive Disorder|Dysthymia|Spinal Cord Injuries
Interventions: DRUG: venlafaxine XR|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ridge Augmentation: Particulate v/s Block Graft
Status: COMPLETED
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: Block allograft|PROCEDURE: Particulate allograft + autogenous bone chips
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma as an Adjunct Therapy at the Time of Transvaginal Native Tissue Prolapse Surgery
Status: RECRUITING
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Platelet rich plasma (PRP) Injection|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Glucocorticoid Therapy on Left Ventricular Remodelling in Acute Myocardial Infarction (RECONSIDER)
Status: UNKNOWN
Conditions: ST-segment Elevation Myocardial Infarction|Left Ventricular Remodeling
Interventions: DRUG: Hydrocortisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Applying Policy to Eliminate or Reduce Inappropriate Narcotics in the General-population
Status: COMPLETED
Conditions: Inappropriate Dose of Drug Administered|Pain, Chronic|Health Behavior
Interventions: OTHER: Direct-to-consumer educational brochure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Peer-led Brief Alcohol Intervention for College Student Drinkers in Spain
Status: COMPLETED
Conditions: Peer Group|Motivational Interviewing|Cognitive Behavioral Therapy|Alcohol Drinking in College
Interventions: BEHAVIORAL: Peer-led BASICS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Anastrazole, Fulvestrant & Abemaciclib for HR+HER2- Metastatic Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Metastatic Breast Cancer|Hormone Receptor-positive Breast Cancer|HER2-negative Breast Cancer
Interventions: DRUG: Fulvestrant|DRUG: Anastrozole|DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Physical and Respiratory Rehabilitation Program for Patients With Persistent COVID-19 (SARS-CoV-2).
Status: NOT_YET_RECRUITING
Conditions: SARS-CoV-2 Infection|COVID-19 Recurrent|Cognitive Dysfunction|Fatigue
Interventions: OTHER: COPERIA-REHAB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: fMRI-neuronavigated rTMS for the Treatment of Major Depression Associated With TBI
Status: TERMINATED
Conditions: Major Depressive Disorder|Traumatic Brain Injury
Interventions: PROCEDURE: Active|PROCEDURE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diclofenac vs. Placebo in a Randomized Double Blind Controlled Trial in Post ERCP Pancreatitis
Status: COMPLETED
Conditions: Post-ERCP Acute Pancreatitis.
Interventions: PROCEDURE: ERCP|DRUG: Diclofenac hydroxyethylpyrrolidine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Improving Vitamin D Status in Home-bound Elders
Status: COMPLETED
Conditions: Vitamin D Deficiency|Accidental Falls
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Cytokine-Induced Memory Like (CIML) Natural Killer (NK) Cells in Recurrent Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Platinum-resistant Ovarian Cancer|Recurrent Ovary Cancer|Ovarian Cancer|Ovarian Carcinoma|Ovarian Carcinoma, Recurrent
Interventions: BIOLOGICAL: Cytokine-Induced Memory-like Natural Killer Cells|BIOLOGICAL: IL-15 Superagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Efficacy and Safety of E2007 in Patients With Painful Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathy
Interventions: DRUG: Placebo|DRUG: E2007 (2 mg)|DRUG: E2007 (4 mg)|DRUG: E2007 (6 mg)|DRUG: E2007 (8 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PilAm Go4Health Weight Loss Program to Prevent Heart Disease
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: BEHAVIORAL: PilAm Go4Health Weight-loss Program|BEHAVIORAL: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Amniotic Fluid Analysis
Status: NOT_YET_RECRUITING
Conditions: Obstetric Labor Complications
Interventions: DEVICE: Intrauterine pressure catheter (IUPC) present|DEVICE: Intrauterine pressure catheter (IUPC) absent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy Study on the Control of Blood Glucose Concentration in Type 1 Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: insulin glulisine / insulin glargine|DRUG: insulin glulisin / insulin detemir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Pivotal Study of SYN010 HFA Inhaler and Symbicort® 160/4.5 in Healthy Volunteers With Charcoal Block
Status: COMPLETED
Conditions: Asthma|Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Budesonide|DRUG: Formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heterologous Boost Immunization With Ad5-nCoV After Three-dose Priming With an Inactivated SARS-CoV-2 Vaccine
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: Ad5-nCoV-IH|BIOLOGICAL: Ad5-nCoV-IM|BIOLOGICAL: CoronaVac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Single-Center, Randomized, Double-Blind, Placebo-Controlled, Two-Way Crossover Study Designed to Evaluate the Efficacy of Fexofenadine HCl 180 mg for Preventing and Controlling Cat Allergy Symptoms
Status: COMPLETED
Conditions: Cat Induced Allergic Rhinitis
Interventions: DRUG: Fexofenadine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Tivantinib and Bevacizumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Solid Neoplasm
Interventions: BIOLOGICAL: Bevacizumab|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Tivantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Tobacco Cut and Nicotine Form on the Abuse Liability of Moist Snuff
Status: NOT_YET_RECRUITING
Conditions: Tobacco-Related Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Carbon Monoxide Measurement|BEHAVIORAL: Smokeless Tobacco Use|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Phase I: At-Home Support for Rural Women Using Group Video Calling
Status: COMPLETED
Conditions: Depression|Post-traumatic Stress Disorder|Recurrent Breast Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer
Interventions: PROCEDURE: support group therapy|OTHER: educational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Lymphoma or Leukemia
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: RADIATION: indium In 111 LL2 IgG|RADIATION: yttrium Y 90 epratuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Detection of Circulating Tumor Cells (CTCs) in Patients With Lung Cancer Undergoing Cryosurgery Combined With DC-CIK Treatment
Status: COMPLETED
Conditions: Neoplastic Cells, Circulating
Interventions: OTHER: Flow cytometry (FCM)|OTHER: RT-PCR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Determining the Mechanisms of Loss of CAR T Cell Persistence
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia With Failed Remission|Acute Lymphoblastic Leukemia Not Having Achieved Remission|Acute Lymphoblastic Leukemia, Pediatric|Acute Lymphoblastic Leukemia, Adult|Acute Lymphoblastic Leukemia, in Relapse
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Intravitreal Microplasmin in Relieving Vitreo-Macular Adhesion in Neovascular Age-related Macular Degeneration
Status: UNKNOWN
Conditions: Macular Degeneration
Interventions: DRUG: Microplasmin|DRUG: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hepatic and Systemic Hemodynamic Modeling During Liver Surgery
Status: RECRUITING
Conditions: Liver Diseases|Liver Transplantation
Interventions: PROCEDURE: Partial hepatectomy (open approach)|PROCEDURE: liver transplantation|PROCEDURE: Portal vein embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Marigot Osteoarthritis Nutritional Intervention (MOANi) Trial
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: Aquamin-Plus|DIETARY_SUPPLEMENT: Glucosamine sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CRD007 for the Treatment of Abdominal Aorta Aneurysm (The AORTA Trial)
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm
Interventions: DRUG: CRD007|DRUG: CRD007 matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Multiple Dose Safety, Tolerability, PK，PD and Food Effect Study of HEC96719 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis (NASH)
Interventions: DRUG: HEC96719
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Importance of Embryo Transfer Day Progesterone Value in Natural Cycle Frozen Embryo Transfers and the Evaluation of the Effect of Rescue Therapy on Pregnancy Outcomes in Patients With Low Progesterone Levels
Status: RECRUITING
Conditions: Infertility|IVF|Progesterone
Interventions: OTHER: Normal Progesterone group|OTHER: Low Progesterone group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of the Safety and Efficacy of Ozarelix in Participants With Benign Prostatic Hyperplasia (BPH)
Status: TERMINATED
Conditions: Benign Prostatic Hyperplasia (BPH)|Lower Urinary Tract Symptoms (LUTS)
Interventions: DRUG: ozarelix|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial of Capecitabine in Combination With Gemcitabine and Erlotinib for Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Carcinoma
Interventions: DRUG: gemcitabine|DRUG: capecitabine|DRUG: erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Schistosoma Mansoni Morbidity in Children Aged 1-5 Years
Status: COMPLETED
Conditions: Intestinal Schistosomiasis
Interventions: DRUG: Praziquantel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Anbainuo in Chinese Patients With RA/AS in the Real World
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Ankylosing Spondylitis
Interventions: DRUG: recombinant TNF-α receptor: IgG Fc fusion protein
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: OC and ICTP in Gingival Crevicular Fluid During Piezocision Accelerated Orthodontic Treatment
Status: COMPLETED
Conditions: Tooth Movement
Interventions: PROCEDURE: Piezocision|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Navitoclax, Venetoclax, and Decitabine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Previously Treated With Venetoclax
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Decitabine|BIOLOGICAL: Navitoclax|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Variceal Ligation in Children
Status: COMPLETED
Conditions: Esophageal Varices in Cirrhosis of the Liver|Upper Gastrointestinal Bleeding|Endoscopy|Child
Interventions: PROCEDURE: Endoscopic Variceal Ligation|DRUG: Non-Selective Beta-Blocking Agent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PET Combined With MRI for Monitoring Inflammatory Activity in Patients With Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DIAGNOSTIC_TEST: [18F]-FDG PET/MRI|DIAGNOSTIC_TEST: Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma
Status: RECRUITING
Conditions: Lymphoma|Lymphoma, B-Cell|Immune System Diseases|Immunoproliferative Disorders|Lymphatic Diseases
Interventions: BIOLOGICAL: iC9-CAR19 T cells|DRUG: Bendamustine|DRUG: Fludarabine|DRUG: AP1903|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Balance and Energetics of Walking Using a Hip Exoskeleton
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: A zero impedance mode, controlling a wearable bilateral hip exoskeleton|OTHER: A personalized optimal assistance mode, controlling a wearable bilateral hip exoskeleton|OTHER: A free walking mode, without wearing a wearable bilateral hip exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring Accessible Beauty for Individuals With Upper Extremity Deficits
Status: COMPLETED
Conditions: Stroke, Ischemic|Stroke Hemorrhagic|Stroke (CVA) or TIA|Stroke, Acute|Traumatic Brain Injury|SCI - Spinal Cord Injury|Ehlers-Danlos Syndromes (EDS)|Lupus Erythematosus|Guillain-Barre Syndrome|Multiple Sclerosis|Myasthenia Gravis|Amyotrophic Lateral Sclerosis|Graves Disease|Muscular Dystrophies
Interventions: OTHER: Use of Rare Beauty makeup products
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Ultrasonic Ablation to Treat Secondary Hyperparathyroidism in Chronic Kidney Disease Patients
Status: COMPLETED
Conditions: Hyperparathyroidism|Disorders of Parathyroid Gland
Interventions: PROCEDURE: Parathyroidectomy|DRUG: Active vitamin D|PROCEDURE: Ultrasonic ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT