pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Safety, Pharmacokinetic and Pharmacodynamic Study of ACP-001 (TransCon hGH) in Adults With Growth Hormone Deficiency
Status: COMPLETED
Conditions: Adult Growth Hormone Deficiency
Interventions: DRUG: ACP-001 (TransCon hGH)|DRUG: ACP-001 (TransCon hGH)|DRUG: ACP-001 (TransCon hGH)|DRUG: Omnitrope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatic Arterial Infusion Chemotherapy(HAIC) for Hepatoma After Resection
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Oxaliplatin(OXA), 5-fluorouracil (5-FU)|PROCEDURE: Hepatic arterial catheter implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety of Lopinavir/Ritonavir (Kaletra) in HIV/HCV Co-infected Subjects vs Baseline Liver Biopsy Metavir Score
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Lopinavir/Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Human Insulin to Insulin Inhalation Solution in Children With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: human insulin|DRUG: inhaled human insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caudal Corticosteroid vs. Dextrose Injection for Lumbosacral Radicular Pain.
Status: UNKNOWN
Conditions: no Conditions
Interventions: PROCEDURE: Epidural Prolotherapy|PROCEDURE: Epidural Steroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A STEP for Patients Prior to Undergoing TAVR: A Pilot Study
Status: TERMINATED
Conditions: Frail Elderly|Aortic Valve Stenosis
Interventions: BEHAVIORAL: Supervised TAVR Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevalence of Steatosis and Steatohepatitis in Patients Undergoing Bariatric Surgery; a Biopsy-based Study
Status: COMPLETED
Conditions: Obesity|Obesity, Morbid|Bariatric Surgery Candidate|Steatosis of Liver|Steatohepatitis, Nonalcoholic
Interventions: PROCEDURE: sleeve gastrectomy|PROCEDURE: Liver Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Testing the Efficacy of Two Behavioral Interventions at Recalibrating Physician Heuristics in Trauma Triage
Status: COMPLETED
Conditions: Wounds and Injuries
Interventions: BEHAVIORAL: Night Shift|BEHAVIORAL: Graveyard Shift|BEHAVIORAL: Educational program|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liquid or Solid State of Food on Glycaemia, Lipaemia and Insulinaemia
Status: COMPLETED
Conditions: Diabetes|Cardiovascular Disease
Interventions: OTHER: Glucose with grass jelly solution|OTHER: Glucose with grass jelly (solid)|OTHER: Porridge and juice with coconut oil|OTHER: Porridge and juice with coconut oil gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy Study of Pioglitazone and Atorvastatin Combination Therapy in Treating Subjects With Elevated Risk for Cardiovascular Disease
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DRUG: Pioglitazone and atorvastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya Disease and Stroke Patients
Status: COMPLETED
Conditions: Cerebrovascular Accident|Moyamoya Disease
Interventions: DRUG: Xenon contrast agent|DEVICE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Food Trial Evaluating the Efficacy of SBD111 Versus Placebo for the Clinical Dietary Management of the Metabolic Processes of Osteopenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteopenia
Interventions: OTHER: Medical Food SBD111|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Blood Flow in the Maturing Arteriovenous Access for Hemodialysis on the Development of Pulmonary Hypertension.
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: PROCEDURE: Primary arterio-venous vascular access creation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Proof of Concept Study to Evaluate the Dose Response for the Systemic Benefit Risk Ratio of Inhaled Fluticasone Propionate in Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Fluticasone propionate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Sedative on the Fluid Responsiveness in Critically Ill Patients
Status: COMPLETED
Conditions: Shock|Sepsis
Interventions: OTHER: Passive Leg Raising|DRUG: propofol or mexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Relative Bioavailability of Single Doses of Dabigatran Etexilate When Administered Alone or in Combination With a Single Dose of Ketoconazole or in Combination With q.d. Ketoconazole at Steady State in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dabigatran etexilate|DRUG: Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shared Decision Making to Improve Goals-of-Care Decisions for Families of Severe Acute Brain Injury Patients
Status: COMPLETED
Conditions: Traumatic Brain Injury|Ischemic Stroke|Intracerebral Hemorrhage
Interventions: OTHER: Decision Aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Prospective Cohort Study of for Surgical Treatment of Irreducible Atlantoaxial Dislocation
Status: NOT_YET_RECRUITING
Conditions: Atlantoaxial Dislocation
Interventions: PROCEDURE: Posterior intra-articular distraction and fusion|PROCEDURE: Anterior transoral release and posterior cantilever reduction and fusion|PROCEDURE: TARP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Search for Biological Markers of Orosensory Perception of Fatty Acids in Healthy Subjects and Possible Modifications in Patients With Type 2 Diabetes and in Obese Non-diabetic Patients.
Status: UNKNOWN
Conditions: Type 2 Diabetes or Obesity Without Diabetes
Interventions: OTHER: Measure the threshold of detection for linoleic acid|OTHER: Oral stimulation tests|OTHER: Venous blood samples|OTHER: Samples for genetic studies (ancillary study)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Carboplatin Intensified Chemotherapy for TRIple NEgative Breast Cancer(CITRINE)
Status: RECRUITING
Conditions: Triple-negative Breast Cancer
Interventions: DRUG: Epirubicin|DRUG: CTX|DRUG: Paclitaxel|DRUG: ddEpirubicin|DRUG: ddCTX|DRUG: Paclitaxel(with carbo)|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy
Status: TERMINATED
Conditions: Mitochondrial Diseases|Drug Resistant Epilepsy|Leigh Disease|Leigh Syndrome|Mitochondrial Encephalopathy (MELAS)|Pontocerebellar Hypoplasia Type 6 (PCH6)|Alpers Disease|Alpers Syndrome
Interventions: DRUG: Vatiquinone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diet and Exercise or Normal Care in Overweight or Obese Women Who Have Undergone Treatment for Stage I, Stage II, or Stage III Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: behavioral dietary intervention|BEHAVIORAL: exercise intervention|OTHER: counseling intervention|OTHER: flow cytometry|OTHER: immunoenzyme technique|OTHER: laboratory biomarker analysis|PROCEDURE: complementary or alternative medicine procedure|PROCEDURE: standard follow-up care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Efficacy, Usability Study of the GlucoTab System for Glycaemic Management in Type 2 Diabetic Patients at General Wards
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DEVICE: GlucoTab System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplementation With Vitamin D3 on Chronic Low Back Pain Patient
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: MPFL vs Campbell in Recurrent Patella Dislocation
Status: UNKNOWN
Conditions: Recurrent Patella Dislocation
Interventions: PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Reducing Blood Pressure in Mid-life Adult Binge Drinkers
Status: RECRUITING
Conditions: Alcohol Drinking|Binge Drinking|Blood Pressure|Alcohol Abstinence|Aging|Lifestyle Factors|Vasodilation|Behavioral Problem
Interventions: BEHAVIORAL: Exercise Training|BEHAVIORAL: Alcohol Abstinence Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2606368 (Prexasertib) in Patients With Solid Tumors With Replicative Stress or Homologous Repair Deficiency
Status: COMPLETED
Conditions: Advanced Cancers
Interventions: DRUG: LY2606368
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ib Study to Determine MTD of AZD1775 Monotherapy in Patients With Locally Advanced or Metastatic Solid Tumours.
Status: COMPLETED
Conditions: Locally Advanced Solid Tumours|Metastatic Solid Tumours|Ovarian Cancer
Interventions: DRUG: AZD1775
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fenretinide in Treating Patients With Cervical Neoplasia
Status: COMPLETED
Conditions: Cervical Cancer|Precancerous Condition
Interventions: DRUG: Fenretinide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Vitamin D in Pediatric Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Vitamin D3: 3000 or 4000 UI/day then 2,000 UI/day|DRUG: Vitamin D3 800 UI/day then 800 UI/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Surinabant Treatment as an Aid to Smoking Cessation (SURSMOKE)
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: surinabant (SR147778)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Music and Maternal Voice on Sedation Depth and Sedative Use During Pediatric Magnetic Resonance Imaging.
Status: COMPLETED
Conditions: Pediatric Solid Tumor|Pediatric Brain Tumor|Pediatric Cancer
Interventions: PROCEDURE: Group headphone|PROCEDURE: Group music|PROCEDURE: Group maternal voice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: XIENCE 28 USA Study
Status: COMPLETED
Conditions: Bleeding Disorder|Ischemic Stroke|Hemorrhagic Stroke|Hematological Diseases|Thrombocytopenia|Coagulation Disorder|Anemia|Renal Insufficiency|Coronary Artery Disease
Interventions: DEVICE: XIENCE|DRUG: DAPT (aspirin and/or P2Y12 receptor inhibitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CORVax12: SARS-CoV-2 Spike (S) Protein Plasmid DNA Vaccine Trial for COVID-19 (SARS-CoV-2)
Status: COMPLETED
Conditions: SARS-CoV-2
Interventions: DRUG: CORVax|DRUG: IL-12 plasmid|DEVICE: Cliniporator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Venetoclax Plus RIC Regimen Allo-HSCT for Elderly Patients With High-risk Myeloid Malignancies
Status: RECRUITING
Conditions: Leukemia, Myeloid, Acute|MDS|Hematopoietic Stem Cell Transplantation|Myeloid Malignancy
Interventions: DRUG: Venetoclax plus RIC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRIMA Intervention for Adults With Mild Cognitive Impairment and Their Caregivers
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Daily Engagement Meaningful Activity (DEMA)|BEHAVIORAL: Information Support (IS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 2 Trial to Evaluate the Efficacy and Safety of Linezolid in Tuberculosis Patients. (LIN-CL001)
Status: COMPLETED
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: Linezolid|DRUG: HRZE (isoniazid rifampicin,pyrazinamide,ethambutol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Steroid Versus Platelet Rich Plasma Injection for Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Pain
Interventions: BIOLOGICAL: Platelet Rich Plasma|BIOLOGICAL: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sweetened Beverages and Food Intake
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: BEHAVIORAL: Fructose|BEHAVIORAL: glucose|BEHAVIORAL: non-caloric sweetener
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigating the Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: DRUG: stannous fluoride|DRUG: sodium monofluorophosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Repeated Oral Doses of JNJ-64281802 Against DENV-3 Challenge
Status: RECRUITING
Conditions: Dengue
Interventions: DRUG: JNJ-64281802 (sentinel high dose)|DRUG: JNJ-64281802 (remaining high dose)|DRUG: JNJ-64281802 (medium/low dose)|DRUG: JNJ-64281802 (daily dosing regimen X)|DRUG: JNJ-64281802 (weekly dosing regimen Y1)|DRUG: JNJ-64281802 (weekly dosing regimen Z2)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Mature B-Cell Non-Hodgkin Lymphoma
Interventions: DRUG: Obinutuzumab|DRUG: Glofitamab|DRUG: Rituximab|DRUG: Ifosfamide|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Losmapimod (GW856553) in Frequently Exacerbating Participants With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Losmapimod tablets|DRUG: Placebo tablets|DRUG: Salbutamol MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Combination of Rad001 and Rituximab In Patients With Non-hodgkin's Lymphomas
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphomas
Interventions: DRUG: Everolimus and rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACAM 3000 MVA at Harvard Medical School
Status: COMPLETED
Conditions: Smallpox
Interventions: BIOLOGICAL: MVA Smallpox Vaccine|BIOLOGICAL: MVA Smallpox Vaccine|OTHER: Placebo|OTHER: Placebo|BIOLOGICAL: MVA Smallpox Vaccine|BIOLOGICAL: Live vaccinia virus vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Nigella Sativa on T Cells and Cytokine Profile in Pediatric SLE Patients
Status: COMPLETED
Conditions: SLE (Systemic Lupus)
Interventions: COMBINATION_PRODUCT: Standard Treatment for SLE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Effectiveness of Add-on Hometreatment to Family Based Therapy in Adolescent Anorexia Nervosa.
Status: RECRUITING
Conditions: Anorexia in Adolescence
Interventions: OTHER: Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Effects of Scalp Block and Intravenous Esmolol on Hemodynamic Response Following the Skull Pins Application for Elective Supratentorial Craniotomy
Status: COMPLETED
Conditions: Hemodynamic Instability
Interventions: PROCEDURE: Scalp block|DRUG: Esmolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CXCR4 Antagonism for Cell Mobilisation and Healing in Acute Myocardial Infarction (CATCH-AMI)
Status: COMPLETED
Conditions: Large Reperfused ST-Elevation Myocardial Infarction
Interventions: DRUG: POL6326|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PY314 in Subjects With Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumor|Gynecologic Cancer|Breast Cancer|Colorectal Cancer|Lung Adenocarcinoma|Renal Cell Carcinoma|Triple Negative Breast Cancer|Hormone Receptor/Growth Factor Receptor-Negative Breast Cancer|Ovarian Cancer
Interventions: DRUG: PY314|DRUG: Combination Therapy: PY314 + Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The PACO Project: A Clinical Study of a PAtient COach Program in Vulnerable Lung Cancer Patients
Status: UNKNOWN
Conditions: Lung Cancer|Social Inequality
Interventions: BEHAVIORAL: Patient coach|BEHAVIORAL: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Flat Polypropylene Mesh in the Treatment of Uterine and Recurrent or Advanced Pelvic Organ Prolapse
Status: ACTIVE_NOT_RECRUITING
Conditions: Pelvic Organ Prolapse
Interventions: DEVICE: Restorelle® Flat Mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Glutamine Supplementation to Prevent Death or Infection in Extremely Premature Infants
Status: COMPLETED
Conditions: Infant, Newborn|Infant, Low Birth Weight|Infant, Small for Gestational Age|Infant, Premature|Sepsis
Interventions: DRUG: Glutamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epidural Anesthesia and Postoperative Analgesia With Ropivacaine and Fentanyl
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: intravenous analgesia|PROCEDURE: epidural infusion|PROCEDURE: patient-controlled epidural analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INCB040093 and INCB040093 Combined With Itacitinib (INCB039110) in Relapsed/Refractory Hodgkin Lymphoma
Status: TERMINATED
Conditions: Refractory Hodgkin Lymphoma|Recurrent Adult Hodgkin's Lymphoma
Interventions: DRUG: INCB040093 Monotherapy|DRUG: INCB040093|DRUG: itacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Maternal Hypotension During Elective Caesarean Section Performed With Spinal Anaesthesia, Through Intermittent Pneumatic Compression System in the Lower Extremities
Status: COMPLETED
Conditions: Hypotension
Interventions: PROCEDURE: Elective caesarean section under spinal anaesthesia.|PROCEDURE: Elective caesarean section under spinal anaesthesia.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Liraglutide in Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: DRUG: Liraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Prednisolone Versus Cerebrolysin in the Treatment of Bell's Palsy
Status: RECRUITING
Conditions: Bell Palsy
Interventions: DRUG: Prednisolone|DRUG: Cerebrolysin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NKTR-102 in Combination With Cetuximab in Patients With Refractory Solid Tumors (Phase 2a) and Metastatic or Locally Advanced Colorectal Cancer (Phase 2b)
Status: COMPLETED
Conditions: Tumor|Colorectal Cancer
Interventions: DRUG: NKTR-102 100 mg/m2|DRUG: NKTR-102 125 mg/m2|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Markers of Alzheimers Disease After Propofol or Isoflurane Anesthesia
Status: COMPLETED
Conditions: General Anesthesia
Interventions: DRUG: Propofol|DRUG: Isoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Diet, Exercise and Vitamin D in Breast Cancer Recurrence
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: OTHER: low Glycemic Index Mediterranean diet|OTHER: Mediterranean diet|BEHAVIORAL: Moderate physical activity|BEHAVIORAL: Basic physical activity|DRUG: high level Vitamin D|DRUG: normal level Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Vertical Implant Position on the Marginal Bone Loss in Thick Versus Thin Phenotype.
Status: RECRUITING
Conditions: Dental Implant|Vertical Position|Esthetic Zone|Bounded Edentulous Area
Interventions: PROCEDURE: Placement of BLX implants 2 mm sub-crestal i|PROCEDURE: Placement of BLX implants equicrestal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Switching From Aflibercept to Ranibizumab in Patients With nAMD
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of an Acetal Resin Crown for Restoration of Primary Molars
Status: COMPLETED
Conditions: Other Unsatisfactory Restoration of Tooth
Interventions: PROCEDURE: Acetal crown, LD Caulk ltd, USA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CYP-001 for the Treatment of Steroid-Resistant Acute Graft Versus Host Disease
Status: COMPLETED
Conditions: Graft vs Host Disease
Interventions: BIOLOGICAL: Mesenchymoangioblast-derived mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stepwise Approach Versus Linear Ablation in Patients With Recurrence of Persistent Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation|Recurrence
Interventions: PROCEDURE: Ablation with stepwise approach|PROCEDURE: Linear ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial to Evaluate the Effectiveness of a Mindfulness Based Intervention (MBSR) for Patients Suffering From Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction MBSR|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BIBW 2992 (Afatinib) in Combination With Pemetrexed in Advanced Solid Tumours
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: BIBW 2992 low dose|DRUG: BIBW 2992 high dose|DRUG: pemetrexed|DRUG: pemetrexed|DRUG: BIBW 2992 high dose 6 day|DRUG: pemetrexed|DRUG: pemetrexed|DRUG: pemetrexed|DRUG: pemetrexed|DRUG: BIBW 2992 low dose 6 day|DRUG: BIBW 2992 medium dose 6 day|DRUG: BIBW 2992 medium dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of BPH With CO2 Serenoa +PEA as Monotherapy or in Combination With Tamsulosin: ProSeRePEA Trial
Status: RECRUITING
Conditions: Benign Prostatic Hyperplasia|Urinary Obstruction|Lower Urinary Tract Symptoms
Interventions: DRUG: PEAPROSTIL 600 + Tamsulosin 0.4 mg|DRUG: Tamsulosin 0.4 mg|DRUG: PEAPROSTIL 600 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Crizotinib as Potentially Targeted Treatment in Cancers With MET Genetic Changes (MATCH - Subprotocol C1)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lymphoma|Advanced Malignant Solid Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Multiple Myeloma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Crizotinib|PROCEDURE: Radiologic Examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tryptophan MRI in People With Schizophrenia and Healthy Controls
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Tryptophan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pain Neurophysiology Education in Combination With Psychologic Inoculation in Chronic Whiplash
Status: UNKNOWN
Conditions: Pain, Chronic|Whiplash Injury
Interventions: BEHAVIORAL: Pain neurophysiology education (PNE) and psychologic inoculation (PI)|BEHAVIORAL: Neck school (NS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determination of the Minimal Concentration of Antifibrinolytics Required to Inhibit t-PA-activated Fibrinolysis
Status: COMPLETED
Conditions: Congenital Heart Disease|Fibrinolysis|Rotational Thromboelastometry
Interventions: OTHER: Intraoperative Blood Sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Caries Inhibition With CO2-Laser During Orthodontic Treatment
Status: UNKNOWN
Conditions: Caries; Initial
Interventions: PROCEDURE: Topical fluoride application and Laser irradiation|PROCEDURE: Topical fluoride application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Safety of MRx0029 or MRx0005 Compared to Placebo, in People With Parkinson's
Status: WITHDRAWN
Conditions: Idiopathic Parkinson Disease
Interventions: BIOLOGICAL: MRx0029|BIOLOGICAL: MRx0005
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prehospital Analgesia INtervention Trial (PAIN)
Status: RECRUITING
Conditions: Traumatic Injury
Interventions: DRUG: Ketamine Hydrochloride|DRUG: Fentanyl Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Early Detection and Treatment of Respiratory Sleep Disorders in Children With Down Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Down Syndrome|Obstructive Sleep Apnea of Newborn
Interventions: DIAGNOSTIC_TEST: Polysomnography (PSG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Online Mindfulness-Based Cognitive Therapy in Depressed Sample
Status: NOT_YET_RECRUITING
Conditions: Moderate Depressive Episode|Mild Depressive Episode
Interventions: BEHAVIORAL: Unguided Mindfulness-Based Cognitive Therapy|BEHAVIORAL: Guided Mindfulness-Based Cognitive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Olverembatinib in the Treatment of Ph+ ALL
Status: NOT_YET_RECRUITING
Conditions: Philadelphia-Positive ALL
Interventions: DRUG: Olverembatinib|DRUG: Prednisone|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain and Nerve Stimulation for Hand Muscles in Spinal Cord Injury and ALS
Status: COMPLETED
Conditions: Spinal Cord Injury (SCI)|Amyotrophic Lateral Sclerosis (ALS)
Interventions: DEVICE: Transcranial magnetic stimulation|DEVICE: Median nerve stimulation|DEVICE: Cervical transcutaneous stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Increased Water Intake on the Frequency of the Clinical Recurrent Urinary Tract Infections in Pre-menopausal Women: S-HYDRACYST
Status: COMPLETED
Conditions: Recurrent Urinary Tract Infection
Interventions: DIETARY_SUPPLEMENT: Mineral water|OTHER: Coaching program|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fecal Microbiota Transplant and Pembrolizumab for Men With Metastatic Castration Resistant Prostate Cancer.
Status: UNKNOWN
Conditions: Prostate Cancer|Prostate Cancer Metastatic
Interventions: BIOLOGICAL: Fecal microbiota transplant|DRUG: Pembrolizumab|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omission of Surgery and Sentinel Lymph Node Dissection in Clinically Low-risk HER2positive Breast Cancer With High HER2 Addiction and a Complete Response Following Standard Anti- HER2-based Neoadjuvant Therapy (ELPIS Trial)
Status: NOT_YET_RECRUITING
Conditions: Mammary Cancer
Interventions: DRUG: Pertuzumab and trastuzumab FDC subcutaneous|DRUG: Paclitaxel|DRUG: TDM1|DRUG: Endocrine therapy|PROCEDURE: Omission surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Nonpharmacological Approaches in Hypertension Prevention and Management
Status: COMPLETED
Conditions: High Blood Pressure|Hypertension
Interventions: OTHER: Educational Intervention Based on Protection Motivation Theory to Improve Knowledge and Promote Nonpharmacological Approaches to Prevent and Manage Hypertension among Adults
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Opioid Free Anesthesia in Abdominal Laparoscopic Surgery
Status: COMPLETED
Conditions: Laparoscopic Surgery|Abdominal Surgery
Interventions: DRUG: Dexmedetomidine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oral Ifetroban in Subjects With Duchenne Muscular Dystrophy
Status: RECRUITING
Conditions: Duchenne Muscular Dystrophy Cardiomyopathy|Cardiomyopathy, Dilated
Interventions: DRUG: Ifetroban|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Calorie Restriction and Brain Function in Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: Meal-Replacement Therapy|BEHAVIORAL: Dietary Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Safety and Pharmacokinetics of AJU-C52L in Healthy Volunteers
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: C52R1H Tab. and C52R2 Tab.|DRUG: AJU-C52L
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food Insecurity Reduction & Strategy Team
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2|Food Insecurity|Diabetes Mellitus, Type 1
Interventions: OTHER: Nutrition program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Benzonatate Dose Tolerance Study
Status: COMPLETED
Conditions: Cough
Interventions: DRUG: Placebo|DRUG: Benzonatate - 400 mg|DRUG: Benzonatate - 600 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: General Plus Spinal Anesthesia and General Anesthesia Alone on Right Ventricular Function
Status: UNKNOWN
Conditions: Right Ventricular Dysfunction
Interventions: PROCEDURE: Spinal anesthesia with Bupivacaine heavy and Morphine|DRUG: Bupivacaine heavy and Morphine|DRUG: General Anesthetics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 3-AP and Gemcitabine in Treating Patients With Recurrent, Unresectable, or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: triapine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Taiwan Based on Medical Records That Looks at the Occurrence of Flare-ups in Patients With Chronic Obstructive Pulmonary Disease (COPD) Who Started LABA/LAMA or LAMA Treatment
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium + Olodaterol|DRUG: Other LABA/LAMA|DRUG: LAMA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PET-CT in Determining the Radioembolization Dose Delivered to Patients With Liver Metastasis, Primary Liver Cancer, or Biliary Cancer
Status: COMPLETED
Conditions: Adult Primary Hepatocellular Carcinoma|Advanced Adult Primary Liver Cancer|Metastatic Extrahepatic Bile Duct Cancer|Recurrent Adult Primary Liver Cancer|Recurrent Extrahepatic Bile Duct Cancer|Stage D Adult Primary Liver Cancer (BCLC)|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: PROCEDURE: PET scan|PROCEDURE: CT Scan|PROCEDURE: hepatic artery embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Artificial Intelligence to Assist the Echocardiographic Identification of Transthyretin Cardiac Amyloidosis
Status: RECRUITING
Conditions: Amyloid Cardiomyopathy|Transthyretin Amyloid Cardiomyopathy|Transthyretin Cardiac Amyloidosis
Interventions: OTHER: non interventional study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial of an Audit and Feedback Report to Improve Colonoscopy Performance
Status: COMPLETED
Conditions: Colorectal Polyps
Interventions: OTHER: Individualized A/F report|OTHER: A/F report plus a high intensity intervention|OTHER: A/F report plus a low intensity intervention|OTHER: A/F report alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Topical Tranexamic Acid Plus Bilateral Uterine Artery Ligation During Cesarean Delivery
Status: UNKNOWN
Conditions: Cesarean Section Complications
Interventions: PROCEDURE: BUA|DRUG: topical tranexamic acid|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Efficacy and Safety of Olmesartan Medoxomil in Children and Adolescent Patients With High Blood Pressure
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: olmesartan medoxomil|DRUG: placebo|DRUG: olmesartan medoxomil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biologics in Refractory Vasculitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Giant Cell Arteritis|Takayasu Arteritis|Cogan Syndrome|Relapsing Polychondritis|Cryoglobulinemic Vasculitis|IgA Vasculitis|Polyarteritis Nodosa|Cutaneous Polyarteritis Nodosa|Primary Angiitis of Central Nervous System
Interventions: BIOLOGICAL: Rituximab|BIOLOGICAL: Infliximab|BIOLOGICAL: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Centering Pre-operative Counseling on Patient Reported Anxiety
Status: COMPLETED
Conditions: Gynecologic Cancer|Ovarian Cancer|Endometrial Cancer|Uterine Cancer|Cervical Cancer
Interventions: BEHAVIORAL: Group pre-operative counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Influenza Vaccine Responses as a Means of Assessing Immune Competence in Chimeric Kidney/Stem Cell Transplant Recipients
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Manual Therapy in Migraine
Status: COMPLETED
Conditions: MIGRAINE
Interventions: OTHER: Sternocleidomastoid MTRP and stretching|OTHER: Trapezius MTRP and stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Modified Integrated Colorectal Cancer Screening System in Saudi Arabia
Status: RECRUITING
Conditions: Colorectal Cancer|Colorectal Neoplasms
Interventions: OTHER: Certain ommunications(Nudge), community-outreach(landline call), and single FIT testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Virtual Reality to Save Morphinic in the Treatment of Vaso-occlusive Seizures of Sickle Cell Patients Consulting in the Emergency Room
Status: COMPLETED
Conditions: Vaso-occlusive Crisis|Sickle Cell Disease
Interventions: DEVICE: Virtual Reality|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Etanercept Plus Methotrexate Versus Methotrexate Alone in Children With Polyarticular Course Juvenile Rheumatoid Arthritis
Status: TERMINATED
Conditions: Juvenile Rheumatoid Arthritis
Interventions: DRUG: Etanercept|DRUG: Placebo to Etanerceot|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Protein Hydrolysate Supplementation Influencing Strength Recovery and Expression of Muscle Damage Markers Post-exercise
Status: COMPLETED
Conditions: Muscle Injury
Interventions: DIETARY_SUPPLEMENT: Elio|OTHER: SMCC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 1 Trial in Patients With Human Papillomavirus (HPV)-Associated Cancer
Status: RECRUITING
Conditions: HPV Associated Cancers
Interventions: DRUG: TGN-S11|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The GCO-002 CACOVID-19 Cohort: a French Nationwide Multicenter Study of COVID-19 Infected Cancer Patients
Status: COMPLETED
Conditions: Cancer|COVID|Solid Tumor|Social Inequality|French National Cohort|Chemotherapy|Immunotherapy|Surgery|Radiotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Omega 7 Oil and Inflammatory Biomarker Study
Status: COMPLETED
Conditions: Musculoskeletal Pain
Interventions: DIETARY_SUPPLEMENT: omega 7|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Standard or Comprehensive Radiation Therapy in Treating Patients With Early-Stage Breast Cancer Previously Treated With Chemotherapy and Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage IB Breast Cancer|Stage II Breast Cancer
Interventions: RADIATION: regional nodal XRT|RADIATION: chestwall XRT|RADIATION: WBI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Various Sealers on Healing of Teeth With Apical Periodontitis
Status: COMPLETED
Conditions: Apical Periodontitis
Interventions: PROCEDURE: Zinc oxide based sealer|PROCEDURE: Epoxy resin based sealer|PROCEDURE: Bioactive silicone based sealer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Irvingia Gabonensis (Bush Mango)on Parameters Associated With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome|Obesity|Dyslipidemia
Interventions: DIETARY_SUPPLEMENT: IGOB131
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise and Dietary Counseling in Improving Physical Activity, Nutrition, and Quality of Life in Older Long-Term Cancer Survivors Who Are Overweight
Status: COMPLETED
Conditions: Breast Cancer|Colorectal Cancer|Prostate Cancer
Interventions: BEHAVIORAL: behavioral dietary and exercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pre- Versus Post-Incisional Epidural Morphine: Higher Postoperative Pain Perception and Extra Morphine Consumption
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: normal saline 3 ml, morphine 3mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Stimulation for Elderly Bipolar Patients
Status: RECRUITING
Conditions: Bipolar Disorder|Cognitive Impairment|Age-related Cognitive Decline
Interventions: BEHAVIORAL: cognitive stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE