pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study to Investigate Effect of Food and Safety of a New Formulation of Zoliflodacin
Status: COMPLETED
Conditions: Gonorrhea
Interventions: DRUG: Zoliflodacin|OTHER: high calorie, high fat breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lapatinib in Combination With Caelyx in Patients With Advanced HER2 Positive Pretreated Breast Cancer
Status: TERMINATED
Conditions: HER-2 Positive Breast Cancer|Malignant Neoplasm of Breast
Interventions: DRUG: Lapatinib, Caelyx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Consequences of Heterozygous Hereditary Fructose Intolerance
Status: COMPLETED
Conditions: Hereditary Fructose Intolerance|Fructose Metabolism, Inborn Errors|Glucose Metabolism Disorders
Interventions: OTHER: Test meal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Tolerability of Hirudoid Cream in Prophylaxis and Treatment Infusion Phlebitis
Status: COMPLETED
Conditions: Thrombophlebitis|Phlebitis
Interventions: DRUG: Hirudoid cream 0.3 % Mucopolysaccharide polysulfate|DRUG: Placebo cream without active substance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Benzodiazepine Taper With Cognitive Behavioral Therapy in Patients Using Prescription Opioids
Status: RECRUITING
Conditions: Anxiety Disorders
Interventions: COMBINATION_PRODUCT: Cognitive behavioral therapy for anxiety plus benzodiazepine taper|COMBINATION_PRODUCT: Health education control plus benzodiazepine taper
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine for the Treatment of Opioid Use Disorder and Depression
Status: COMPLETED
Conditions: Depression|Opioid-use Disorder|Opioid Abuse
Interventions: DRUG: Ketamine Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Safety of the Sonitus SoundBite System
Status: COMPLETED
Conditions: Hearing Loss|Unilateral Hearing Loss|Total Unilateral Deafness
Interventions: DEVICE: Sonitus SoundBite System|DEVICE: SoundBite Hearing System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repeat Dose Study of GSK3772847 in Participants With Moderate to Severe Asthma With Allergic Fungal Airway Disease (AFAD)
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: GSK3772847|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Colon, Pancreatic, or Lung Cancer
Status: COMPLETED
Conditions: Recurrent Colon Cancer|Extensive Stage Small Cell Lung Cancer|Stage III Pancreatic Cancer|Stage III Rectal Cancer|Limited Stage Small Cell Lung Cancer|Recurrent Pancreatic Cancer|Recurrent Rectal Cancer|Stage III Non-small Cell Lung Cancer|Stage I Pancreatic Cancer|Stage II Non-small Cell Lung Cancer|Stage IVB Pancreatic Cancer|Stage II Pancreatic Cancer|Stage III Colon Cancer|Stage IVA Pancreatic Cancer
Interventions: DRUG: Detox-B adjuvant|DRUG: ras peptide cancer vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Nifedipine Versus Magnesium Sulfate for Late Preterm Tocolysis
Status: RECRUITING
Conditions: Threatened Preterm Labor
Interventions: DRUG: Nifedipine 20 Mg|DRUG: Magnesium Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2b/3a Study to Evaluate the Efficacy and Safety of JointStem in Patients Diagnosed as Knee Osteoarthritis
Status: RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: DRUG: JointStem|OTHER: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential ATRA Then IL-2 for Modulation of Dendritic Cells and Treatment of Metastatic Renal Cell Cancer
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: DRUG: IL-2|DRUG: ATRA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-modal Exercise Program in Older Aduls With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: OTHER: Multi-modal exercise program|OTHER: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Diet and Exercise or Standard of Care in Improving Physical Function and Quality of Life in Patients With Prostate Cancer Undergoing Androgen Deprivation Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: BEHAVIORAL: behavioral dietary intervention|BEHAVIORAL: exercise intervention|OTHER: behavioral activity counseling|BEHAVIORAL: telephone based counseling|PROCEDURE: quality-of-life assessment|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Videolaryngoscopes With Manual In-line Stabilization
Status: COMPLETED
Conditions: Oral Surgery|Maxillofacial Surgery
Interventions: PROCEDURE: MILS|DEVICE: McGrath videolaryngoscope|DEVICE: Pentax AWS videolaryngoscope|DEVICE: Macintosh laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pathophysiological Mechanisms of Hepatopulmonary Influence in the Fontan Circulation
Status: COMPLETED
Conditions: Children With a Univentricular Heart Undergoing Surgery for Creation of a Fontan Circulation
Interventions: DRUG: Administration of an ACE-inhibitor or not
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hematopoietic Stem Cell Transplantation for Treatment of Multiple Sclerosis in Sweden
Status: COMPLETED
Conditions: Multiple Sclerosis|Multiple Sclerosis, Relapsing-Remitting
Interventions: PROCEDURE: Autologous hematopoietic stem cell transplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Medical Assistant-Based Program to Promote Healthy Behaviors in Primary Care
Status: COMPLETED
Conditions: Smoking|Problem Drinking|Sedentary Lifestyle|Unhealthy Diet
Interventions: BEHAVIORAL: Intervention for 4 behavioral risks by medical assistants.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Enhancing Source Credibility in Tobacco Regulatory Communications
Status: COMPLETED
Conditions: Cigarette Smoking Behavior
Interventions: BEHAVIORAL: Constituent message with FDA and quitline|BEHAVIORAL: Constituent message without FDA and quitline|BEHAVIORAL: Littering message (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combined 3D Power Doppler Placental Volume and Vascular Flow Indices In the First Trimester of Pregnancy as Predictors Of Preeclampsia?.
Status: UNKNOWN
Conditions: Preeclampsia
Interventions: DEVICE: 2D ultrasound|DEVICE: Doppler Ultrasound|DEVICE: 3D ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Electronic Cleansing Toilet System (Bidet) on Anal Resting Pressure
Status: COMPLETED
Conditions: Anorectal Physiology
Interventions: DEVICE: Bidet (electronic cleansing toilet system)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas
Status: ACTIVE_NOT_RECRUITING
Conditions: Neurofibromatosis Type 1|Plexiform Neurofibroma
Interventions: DRUG: Binimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: (SBRT) and (ART) for Pulmonary Metastases From Soft Tissue Sarcomas
Status: COMPLETED
Conditions: Stage IV Adult Soft Tissue Sarcoma|Sarcoma,Soft Tissue
Interventions: RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening for Swallowing Problems in Patients Following Prolonged Intubation: Validation of the Toronto Bedside Swallowing Screening Test (TOR-BSST©)
Status: COMPLETED
Conditions: Dysphagia
Interventions: OTHER: Toronto Bedside Swallowing Screening Test (TOR-BSST©)|PROCEDURE: Videofluoroscopic Swallow Study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Direct Intra-arterial Thrombectomy in Order to Revascularize AIS Patients With Large Vessel Occlusion Efficiently in Chinese Tertiary Hospitals
Status: COMPLETED
Conditions: Ischemic Stroke|Large Vessel Occlusion|Thrombectomy|Thrombosis|Alteplase
Interventions: PROCEDURE: intra-arterial thrombectomy|DRUG: Intravenous thrombolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fludarabine and Cyclophosphamide Followed By LMB-2 Immunotoxin in Treating Patients With Hodgkin's Lymphoma
Status: WITHDRAWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: LMB-2 immunotoxin|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Impact of Anterior Abdominal Wall Tissue Oxygenation During Pneumoperitoneum of Regional Anesthesia Methods
Status: UNKNOWN
Conditions: Laparoscopy|Abdominal Wall|Regional Anesthesia
Interventions: DEVICE: regional oxymetry probe|PROCEDURE: Quadratus Lumborum block|PROCEDURE: Thoracic Epidural block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Safety and Use of Human Rhinovirus in Healthy and Asthmatic Participants (MK-0000-218)
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: RV16UB|DRUG: LABA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Feasibility and Efficacy of Sulforaphane (Avmacol Extra Strength) in Chronic Kidney Disease
Status: RECRUITING
Conditions: Chronic Kidney Disease Stage 3|Chronic Kidney Disease Stage 4
Interventions: DRUG: Sulforaphane (Avmacol Extra Strength)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetes: Functional Medicine Approach vs. Usual Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes|Type 2 Diabetes|Type 2 Diabetes Treated With Insulin
Interventions: DIETARY_SUPPLEMENT: Functional Medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Pilot Study of a Non-Narcotic Post-Operative Course After Colectomy
Status: RECRUITING
Conditions: Analgesia|Post-Operative Pain|Breakthrough Pain|Colectomy
Interventions: OTHER: Non-Narcotic ERAS Post-Operative Pain Management
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compassionate Use of Metreleptin in Previously Treated People With Partial Lipodystrophy
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes|Lipodystrophy|Hyperlipidemia
Interventions: DRUG: Metreleptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Open-Label, Multi-Center Study To Evaluate The Efficacy And Safety Of Intramuscular Ziprasidone In Patients With Agitation
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Intramuscular ziprasidone mesylate|DRUG: Intramuscular haloperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promotion of a Physically Active Lifestyle in Cerebral Palsy
Status: UNKNOWN
Conditions: Cerebral Palsy (CP)
Interventions: DEVICE: TreadMill|OTHER: Physical activity in groups|BEHAVIORAL: Monitoring physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: QUILT-2.015: A Study of AMG 479 With Exemestane or Fulvestrant in Postmenopausal Women With Hormone Receptor Positive Locally Advanced or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Breast Tumors|Metastatic Cancer
Interventions: DRUG: AMG 479 or placebo administered with either exemestane or fulvestrant|DRUG: AMG 479 or placebo administered with either exemestane or fulvestrant|DRUG: AMG 479 or placebo administered with either exemestane or fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mobilizing Hispanics With Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: BEHAVIORAL: Muscle Strengthening|BEHAVIORAL: General Physical Activity|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Intravenous Albumin Replacement During Abdominal Paracentesis in Patients With Malignancy Related Ascites
Status: UNKNOWN
Conditions: Ascites|Hypotension
Interventions: PROCEDURE: Receives IV albumin infusion|BIOLOGICAL: Do not receive IV albumin infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Imaging Biomarkers for Immune Checkpoint Inhibitor Treatment in Patients With Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung|Immune Checkpoint Inhibitors
Interventions: DIAGNOSTIC_TEST: F-18 FDG PET/CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preemptive Versus Preventive Antiemetic Treatment
Status: UNKNOWN
Conditions: Postoperative Nausea and Vomiting
Interventions: OTHER: Antiemetics perioperatively
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nicotine Pharmacokinetic Profile and Safety of the Tobacco Heating System 2.2 Menthol (THS 2.2 Menthol).
Status: COMPLETED
Conditions: Smoking
Interventions: OTHER: mTHS|OTHER: mCC|OTHER: NRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Moxibustion for Primary Dysmenorrhea
Status: COMPLETED
Conditions: Primary Dysmenorrhea
Interventions: DEVICE: moxibustion|DRUG: Ibuprofen Sustained Release Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MM-121 With Paclitaxel in Platinum Resistant/ Refractory Advanced Ovarian Cancers
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: DRUG: MM-121|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Dose of AMG 609 in Participants With Non-alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DRUG: AMG 609|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Role of Auditory Feedback in Guiding Upper Extremity Movements
Status: UNKNOWN
Conditions: Stroke
Interventions: BEHAVIORAL: Auditory Feedback 100%|BEHAVIORAL: Auditory Feedback 50% alternate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical and Pharmacogenetic Study of Attention Deficit With Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Ritalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lysophosphatidic Acid Assay in Patients With Ovarian Cancer or Who Are at Risk for Ovarian Cancer
Status: COMPLETED
Conditions: brca1 Mutation Carrier|brca2 Mutation Carrier|Ovarian Cancer
Interventions: DIAGNOSTIC_TEST: Biomarker LPA and HE4
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Placebo Controlled Study of ATH008 Cream in PPES Patients Secondary to Capecitabine
Status: COMPLETED
Conditions: Palmar-Plantar Erythrodysesthesia Syndrome
Interventions: DRUG: ATH008
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Daily Vinegar Ingestion for Four Weeks on Mood State in Healthy College Students
Status: COMPLETED
Conditions: Mood|Depression
Interventions: DIETARY_SUPPLEMENT: apple cider vinegar|DIETARY_SUPPLEMENT: vinegar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Elbasvir (EBR)/Grazoprevir (GZR) in Pediatric Participants With Chronic Hepatitis C Infection (MK-5172-079)
Status: COMPLETED
Conditions: HCV Infection
Interventions: DRUG: EBR/GZR FDC Tablet|DRUG: Placebo|DRUG: Grazoprevir Oral Granules|DRUG: Elbasvir Oral Granules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Short and Standard Dental Implants
Status: COMPLETED
Conditions: Peri-Implantitis|Peri-implant Mucositis
Interventions: OTHER: PICF (Periopaper)|OTHER: Subgingival plaque, Gracey curette (Hu-Friedy)|OTHER: Clinical data, williams probe PCPNU (Hu-Friedy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cryotherapy Versus Radiofrequency Ablation for Treatment of Para-hisian Accessory Pathways
Status: COMPLETED
Conditions: Cardiac Arrhythmias|Accessory Pathway|Wolf Parkinson White Syndrome
Interventions: DEVICE: Radiofrequency (RF)|DEVICE: Cryotherapy (CRYO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transplantation of Vaginal Mikrobiome
Status: COMPLETED
Conditions: Vaginal Dysbiosis|Vaginal Microbiome|Transplantation
Interventions: BIOLOGICAL: Vaginal Microbiome Transplant|BIOLOGICAL: Vaginal Microbiome Transplant Placebo|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Femoral Quadriceps Muscle Length on Fatigue Induced by Neuromuscular Electrical Stimulation
Status: NOT_YET_RECRUITING
Conditions: Electrical Stimulation
Interventions: OTHER: Electrical estimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma
Status: NOT_YET_RECRUITING
Conditions: Metastatic Uveal Melanoma
Interventions: BIOLOGICAL: RP2|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutrition Interventions to Support the Immune System in Response to Stress
Status: COMPLETED
Conditions: Mitigation of Immune Function Decrements in Response to Stress
Interventions: DIETARY_SUPPLEMENT: Immune-enhancing nutritional beverage|DIETARY_SUPPLEMENT: Probiotics (BB-12)|DIETARY_SUPPLEMENT: Placebo (for nutritional beverage and probiotic)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Therapeutic Relationship Between the Case Manager and the Person With Severe Mental Health Disorder
Status: RECRUITING
Conditions: Mental Health Disorder|Case Management|Psychiatric Nursing
Interventions: BEHAVIORAL: Participatory action research
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of a Cincalcet Suppression Test
Status: COMPLETED
Conditions: Parathyroid Hormone Suppression Test With Cinacalcet
Interventions: DRUG: cinacalcet|DRUG: cinacalcet dose 1|DRUG: cinacalcet dose 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study to Evaluate the Plasma Profile of Revifast
Status: COMPLETED
Conditions: Nutrient; Excess|Product Use Issue
Interventions: DIETARY_SUPPLEMENT: Revifast|DIETARY_SUPPLEMENT: pure resveratrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating Use of Microwave Technology to Differentiate Hemorrhagic Stroke From Infarction in the Acute Phase
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: Strokefinder MD100 measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Home-based Proprioceptive Neuromuscular Facilitation for Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus|Exercise
Interventions: BEHAVIORAL: lifestyle changes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Study of Pseudoephedrine for the Temporary Relief of Nasal Congestion in Children With the Common Cold
Status: COMPLETED
Conditions: Nasal Congestion Associated With the Common Cold
Interventions: DRUG: pseudoephedrine hydrochloride 30 mg tablets|DRUG: Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intracranial PrEssure Time dOse (ImPETO)
Status: RECRUITING
Conditions: Intracranial Hypertension|Traumatic Brain Injury|Subarachnoid Hemorrhage|Intracranial Hemorrhages
Interventions: PROCEDURE: intracranial pressure monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Registry: TPLA for LUTS
Status: NOT_YET_RECRUITING
Conditions: Lower Urinary Tract Symptoms|Benign Prostate Hyperplasia|Benign Prostatic Hypertrophy With Outflow Obstruction
Interventions: PROCEDURE: Transperineal Laser Ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Application of a Wireless Sensor Technology for Vital Statistics in CHILDREN AND ADULTS
Status: UNKNOWN
Conditions: Fever|COPD|Obesity|Congenital Heart Disease|Respiratory Distress
Interventions: DEVICE: Cardiorespiratory monitor|DEVICE: Wireless pressure sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: End-range Maitland Mobilization on Glenohumeral Internal Rotation Deficit and Proprioception
Status: COMPLETED
Conditions: Sports Physical Therapy
Interventions: PROCEDURE: End-range Maitland mobilization + proprioception training|PROCEDURE: Non end-range Maitland mobilization + proprioception training|PROCEDURE: Sham manual therapy technique + proprioception training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Using Changes in Serum BCMA to Determine Disease Progression in Multiple Myeloma
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Ruxolitinib Oral Tablet [Jakafi]|DRUG: Lenalidomide|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of "OncozeneTM" Microspheres for Intra-arterial Delivery of Doxorubicin
Status: COMPLETED
Conditions: Hepatocellular Cancer
Interventions: OTHER: Oncozene-DEB-TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study on Adjuvant Vaccination With Dendritic Cells Loaded With Autologous Tumor Homogenate in Resected Stage IV Rare Cancers.
Status: RECRUITING
Conditions: Head Neck Tumors|Neuroendocrine Tumors|Soft Tissue Sarcoma|Rare Cancer|Vaccination
Interventions: BIOLOGICAL: Autologous DC vaccine|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alectinib Pharmacokinetic in Patients With NSCLC
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer Stage IIIB|ALK Gene Mutation
Interventions: DRUG: Alectinib Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Focused Shockwave Therapy Plus Tadalafil vs Tadalafil Alone in Patient With Erectile Dysfunction
Status: RECRUITING
Conditions: Erectile Dysfunction
Interventions: COMBINATION_PRODUCT: PDE5 inhibitor (tadalafil) and BTL-6000 fSWT|DRUG: PDE5 inhibitor (tadalafil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: XNKQ Acupuncture Compared to Control Interventions Measured With EEG and fMRI
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: XNKQ|OTHER: Control 1|OTHER: Control 2|OTHER: Control 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Side Effects of Newer Antipsychotics in Older Adults
Status: COMPLETED
Conditions: Schizophrenia|Alzheimer's Disease|Dementia
Interventions: DRUG: Aripiprazole|DRUG: Olanzapine|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: mHealth to Enhance & Sustain Drug Use Reduction of the QUIT BI in Primary Care
Status: RECRUITING
Conditions: Drug Use
Interventions: BEHAVIORAL: Usual Care|BEHAVIORAL: QUIT Intervention (doctor brief advice, video doctor, health coaching sessions at 2- and 6-weeks)|BEHAVIORAL: QUIT-Mobile (QUIT Intervention plus weekly mobile-web app or text message weekly self-monitoring, automated feedback over 12 months)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Mesenchymal Stem Cells for Treatment of Poor Graft Function After Allogeneic Hematopoietic Stem Cell Transplantation
Status: NOT_YET_RECRUITING
Conditions: MSC
Interventions: BIOLOGICAL: mesenchymal stromal cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebellar Non-invasive Stimulation in Ataxias
Status: UNKNOWN
Conditions: Cerebellar Ataxia
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS)|DEVICE: Sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Osteoporosis in Breast Cancer Survivors
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: OTHER: Strength/Weight Training & Drug/Supplement|COMBINATION_PRODUCT: Drug/Supplement only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dose Ranging Efficacy And Safety With Mepolizumab in Severe Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: Mepolizumab 750|BIOLOGICAL: Mepolizumab 250|BIOLOGICAL: Mepolizumab 75|DRUG: Placebo saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Nitric Oxide in Acute Ischemic Stroke Patients Undergoing Mechanical Thrombectomy
Status: NOT_YET_RECRUITING
Conditions: Cerebrovascular Disorders|Acute Cerebrovascular Disease
Interventions: DRUG: iNO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Efficacy and Safety of Ezetimibe/Rosuvastatin and Candesartan Cilexetil/Amlodipine Besylate Combination Tablets
Status: COMPLETED
Conditions: Hypertension, Hyperlipidemia
Interventions: DRUG: Ezetimibe/Rosuvastatin|DRUG: Candesartan cilexetil/Amlodipine besylate|DRUG: Candesartan cilexetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Selective and Nonselective Cyclooxygenase Enzyme Inhibition on Arterial Blood Pressure and Cerebral Blood Flow With Exposure to Intermittent Hypoxia in Humans
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Hypertension|Cardiovascular Diseases|Stroke
Interventions: OTHER: Intermittent hypoxia|DRUG: Indomethacin|DRUG: Celecoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: 3D Printed Model Simulator or Virtual Reality Software for Training Fiberoptic Intubation Skill
Status: COMPLETED
Conditions: Intubation, Endotracheal
Interventions: OTHER: 3D-printed airway simulator|OTHER: virtual reality software, AirwayEx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Fibrinogen Concentrate in Aortic Arch Surgery Involving Moderate Hypothermic Circulatory Arrest
Status: UNKNOWN
Conditions: Proximal Aortic Dissection
Interventions: DRUG: fibrinogen concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of The Effect of Loratadine Versus Diosmin/Hesperidin Combination on Vinca Alkaloids Induced Neuropathy
Status: UNKNOWN
Conditions: Vinca Alkaloid Adverse Reaction
Interventions: DRUG: Loratadine|DRUG: Diosmin/ Hesperidin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mindfulness Engaged Neurostimulation for Depression
Status: RECRUITING
Conditions: Depression|Treatment Resistant Depression|Major Depressive Disorder|Depressive Disorder
Interventions: COMBINATION_PRODUCT: Medi-TBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AN OPEN-LABEL, ACUTE CLINICAL TRIAL TO ASSESS THE LEVEL OF KETONE PRODUCTION FOLLOWING CONSUMPTION OF AVELA™ (R)-1,3-BUTANEDIOL IN AN ADULT POPULATION
Status: UNKNOWN
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: (R)-1,3-butanediol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pilot Study of The EPIC Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Sinusitis|Nasal Polyps
Interventions: PROCEDURE: Endoscopic Polypectomy Performed in Clinic|PROCEDURE: Functional Endoscopic Sinus Surgery (FESS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Extension of CP101 Trials Evaluating Oral Full-Spectrum Microbiota™ (CP101) in Subjects With Recurrence of Clostridium Difficile Infection
Status: COMPLETED
Conditions: Clostridium Difficile Infection|Recurrent Clostridium Difficile Infection|C. Diff|CDI|Recurrent C. Diff|rCDI|C. Difficile|Recurrent CDI|FMT|Fecal Microbiota|Fecal Transplant
Interventions: BIOLOGICAL: CP101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcome of Two-piece Zirconia Implants in Immediate Implant Placement
Status: RECRUITING
Conditions: Immediate Implantation of Two-piece Zirconia Dental Implants
Interventions: DEVICE: Implant Straumann® Pure Ceramic Two Piece Implant|DEVICE: two-piece titanium implant Neoss® ProActive Tapered Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Hyoscine Butyl Bromide Versus Diclofenac Potassium Before Office Hysteroscopy
Status: COMPLETED
Conditions: Endoscopy
Interventions: DRUG: diclofenac potassium|DRUG: hyoscine butyl bromide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Single Dose Study of LY2605541 in Participants With Liver Impairment
Status: COMPLETED
Conditions: Healthy Volunteers|Hepatic Insufficiency|Diabetes Mellitus, Type 2
Interventions: DRUG: LY2605541
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transoral Robotic Surgery and Tailored Radiotherapy in Unknown Primary and Small Squamous Cell Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: OTHER: da Vinci Surgical System Model IS4000
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole Body Vibration After Bariatric Surgery
Status: RECRUITING
Conditions: Bariatric Surgery and Whole Body Vibration Training|Bariatric Surgery
Interventions: DEVICE: Whole body vibration training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Survival Study in Patients With High Risk Myelodysplastic Syndromes Comparing Azacitidine Versus Conventional Care
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Azacitidine|OTHER: Physician Choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vitamin A and D Supplementation in Allogeneic HCT
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Biphenotypic Acute Leukemia|Lymphoblastic Lymphoma|Chronic Myeloid Leukemia|Myelodysplastic Syndromes|Myeloprolipherative Neoplsm|Non-hodgkin Lymphoma
Interventions: DRUG: Vitamin A|DRUG: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Watching Cartoons and Playing Games as Distraction Method During Peripheral Intravenous Cannula Placement on Pain and Fear in Children Aged 6-9 Years
Status: RECRUITING
Conditions: Procedural Pain|Fear of Pain
Interventions: BEHAVIORAL: Playing game|BEHAVIORAL: Watching cartoon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Microfracture Treatment and CARTIPATCH® Chondrocyte Graft Treatment in Femoral Condyle Lesions
Status: TERMINATED
Conditions: Knee Chondral|Osteochondral Defect
Interventions: PROCEDURE: CARTIPATCH® procedure|PROCEDURE: Microfracture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decreasing Patient Anxiety During Revascularization of Chronic Total Coronary Occlusions Using Virtual Reality Glasses.
Status: UNKNOWN
Conditions: Chronic Total Occlusion|Anxiety
Interventions: OTHER: Virtual reality headset during percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cross-training Effect of Whole-body Vibration
Status: COMPLETED
Conditions: Muscle Physiology
Interventions: DEVICE: Whole body vibration|DEVICE: Sham vibration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Insulin Detemir Produced by the Current Process and the NN729 Process in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: insulin detemir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin ± Aspirin in Lynch Syndrome Syndrome
Status: RECRUITING
Conditions: Lynch Syndrome
Interventions: DRUG: Atorvastatin 20mg|DRUG: Atorvastatin 20mg AND Aspirin 325 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Long-term Efficacy and Safety Study of TAK-085 in Participants With Hypertriglyceridemia
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DRUG: omega-3-acid ethyl esters 90 (TAK-085)|DRUG: Eicosapentaenoic acid-ethyl (EPA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anticaries Effect of Probiotic Lactobacillus Brevis CD2 (Lb CD2).
Status: UNKNOWN
Conditions: Dental Caries|Gingivitis
Interventions: DIETARY_SUPPLEMENT: lozenges
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Facing Eating Disorder Fears for Anorexia Nervosa
Status: RECRUITING
Conditions: Eating Disorders|Anorexia Nervosa|Anorexia Nervosa in Remission
Interventions: BEHAVIORAL: Facing Eating Disorder Fears Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Following of Atmospheric Pollution Exposure During Pregnancy and Effects on Health
Status: UNKNOWN
Conditions: Healthy Volunteer
Interventions: OTHER: Urine sampling|OTHER: Carry a GPS and BET|OTHER: Carry pollution sensor|OTHER: Sampling at the maternity|OTHER: Self-questionnaires|OTHER: Sampling in partum period
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Polyacrylamide Hydrogel Injection Treatment for Anal Incontinence
Status: COMPLETED
Conditions: Anal Incontinence
Interventions: PROCEDURE: Transanal submucosal injection group 1|PROCEDURE: Transanal submucosal injection group 2|PROCEDURE: Transanal submucosal injection group 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effect of Intravascular Laser Irradiation of Blood
Status: UNKNOWN
Conditions: Low-Level Laser Therapy
Interventions: DEVICE: Intravascular laser irradiation of blood for the patients with cerebral infarction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Effects of Teleconsultations on a Endocrinology Referral List
Status: COMPLETED
Conditions: Diabetes Mellitus|Hypothyroidism|Hyperthyroidism|Goiter|Thyroid Nodule|Obesity
Interventions: OTHER: Teleconsultation|OTHER: Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TIL Therapy Combined With Pembrolizumab for Advanced or Metastatic Refractory Stomach and Esophageal Cancer
Status: NOT_YET_RECRUITING
Conditions: Stomach Cancer|Stomach Cancer Recurrent|Stomach Cancer, Adenocarcinoma|Esophageal Cancer|Esophageal Cancer Metastatic to Bone|Esophageal Cancer Metastatic to Lung|Esophageal Cancer Metastatic to Liver
Interventions: BIOLOGICAL: Tumor Infiltrating Lymphocytes (TIL)|DRUG: Cyclophosphamid|DRUG: Fludarabine|DRUG: Interleukin-2|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating High Risk Leukemia With CD40 Ligand & IL-2 Gene Modified Tumor Vaccine
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: Dose Level 1|BIOLOGICAL: Dose Level 2|BIOLOGICAL: Dose Level 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive-Behavioral Therapy and Hypnotherapy for Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Cognitive-Behavioral Therapy|BEHAVIORAL: Hypnotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nab-Paclitaxel Plus Gemcitabine Versus Gemcitabine For The First Line Treatment of Pancreas Cancer
Status: COMPLETED
Conditions: Pancreatic Neoplasm
Interventions: DRUG: Nab-paclitaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Volatility and Heterogeneity of Vaccine Sentiments Means Continuous Monitoring is Needed When Measuring Message Effectiveness
Status: COMPLETED
Conditions: Vaccine-Preventable Diseases|Vaccine Refusal
Interventions: BEHAVIORAL: Google ads
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Physiotherapy-led Disease-agnostic Telerehabilitation Programme for People With Chronic Health Conditions
Status: RECRUITING
Conditions: Chronic Conditions, Multiple
Interventions: OTHER: TECC (Telerehabilitation and Exercise for Chronic Conditions)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Multiple Rising Oral Doses of BI 1015550 Powder for Oral Solution
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: BI 1015550|DRUG: BI 1015550|DRUG: BI1015550|DRUG: BI 1015550
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate How a Drug That Alters Liver Enzymes (Rifampin) Affects the Metabolism of Enzalutamide in Men
Status: COMPLETED
Conditions: Drug-Drug Interaction (DDI)|Healthy Subjects|Pharmacokinetics of Enzalutamide
Interventions: DRUG: enzalutamide|DRUG: rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose Escalation, Randomized Controlled Trial to Evaluate the Safety, Immunogenicity and Efficacy of Intravenously Administered Attenuated Plasmodium Falciparum Sporozoite Vaccine (PfSPZ Vaccine) in Tanzanian Adults
Status: COMPLETED
Conditions: Malaria|Plasmodium Falciparum Malaria
Interventions: BIOLOGICAL: PfSPZ Vaccine|BIOLOGICAL: Normal Saline (Placebo)|BIOLOGICAL: PfSPZ Challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Viral Therapy in Treating Patients With Recurrent Glioblastoma Multiforme
Status: COMPLETED
Conditions: Anaplastic Astrocytoma|Anaplastic Oligodendroglioma|Mixed Glioma|Recurrent Glioblastoma
Interventions: BIOLOGICAL: Carcinoembryonic Antigen-Expressing Measles Virus|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Various External Pressure on Blood
Status: COMPLETED
Conditions: Hemorrhage
Interventions: DEVICE: Auto PC(Acemedical, Goyang-si, Korea) - 0mmHg(control)|DEVICE: Auto PC(Acemedical, Goyang-si, Korea) - 150mmHg|DEVICE: Auto PC(Acemedical, Goyang-si, Korea) - 200mmHg|DEVICE: Auto PC(Acemedical, Goyang-si, Korea) - 250mmHg|DEVICE: Auto PC(Acemedical, Goyang-si, Korea) - 300mmHg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE