pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Manipulation Under Anesthesia Versus Arthroscopic Capsular Release in the Treatment of Adhesive Capsulitis
Status: TERMINATED
Conditions: Adhesive Capsulitis of the Shoulder
Interventions: PROCEDURE: Manipulation Under Anesthesia|PROCEDURE: Arthroscopic capsular release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Human Zinc Absorption From Wheat-based Meals
Status: COMPLETED
Conditions: Zinc Deficiency
Interventions: DIETARY_SUPPLEMENT: Biofortified wheat|DIETARY_SUPPLEMENT: Fortified wheat|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Pregabalin and Duloxetine in Patients With PDPN: the Effect of Pain on Cognitive Function, Sleep and Quality of Life
Status: TERMINATED
Conditions: Painful Diabetic Peripheral Neuropathy
Interventions: DRUG: Pregabalin|DRUG: Duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 153Sm-EDTMP With or Without a PSA/TRICOM Vaccine To Treat Men With Androgen-Insensitive Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: RADIATION: Samarium Sm 153 lexidronam pentasodium|BIOLOGICAL: Sargramostim|BIOLOGICAL: Recombinant vaccinia-TRICOM vaccine|BIOLOGICAL: Recombinant fowlpox-TRICOM vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Dose and DDI Study
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Placebo|DRUG: PF-06835919|DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: S1211 Bortezomib, Dexamethasone, and Lenalidomide With or Without Elotuzumab in Treating Patients With Newly Diagnosed High-Risk Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: DS Stage I Plasma Cell Myeloma|DS Stage II Plasma Cell Myeloma|DS Stage III Plasma Cell Myeloma
Interventions: DRUG: Bortezomib|DRUG: Dexamethasone|BIOLOGICAL: Elotuzumab|OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selective Removal Technique With or Without a Bioactive Material for Deep Caries Lesions
Status: RECRUITING
Conditions: Deep Caries
Interventions: PROCEDURE: Selective removal to soft dentin, Biodentine|PROCEDURE: Selective removal to soft dentin, No Base
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Applicability and Acceptability of an Algorithm to Guide the Prescription of 1st and 2nd Generation Cephalosporins as Part of Intraoperative Antibiotic Prophylaxis in Patients With a Declared Allergy to Penicillin
Status: RECRUITING
Conditions: Adult Patients Who Declare an Allergy to Penicillin During Anaesthetic Consultation Without Any Allergy Work up That Could Confirm This Declaration|Good Comprehension of French Language
Interventions: OTHER: decision tree for the choice of intraoperative antibiotic prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 1/2a Study Evaluating Allocetra-OTS as Monotherapy or in Combination With Anti-PD-1 Therapy for the Treatment of Advanced Solid Tumor Malignancy
Status: TERMINATED
Conditions: Solid Tumor|Peritoneal Metastases|Peritoneal Cancer
Interventions: DRUG: Allocetra-OTS|DRUG: Nivolumab|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of "Gam-COVID-Vac" Vaccine Against COVID-19 With the Participation of Volunteers of 60 y.o and Older
Status: UNKNOWN
Conditions: Coronavirus Infection
Interventions: BIOLOGICAL: Gam-COVID-Vac
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Imupret Application in the Technology of Delayed Prescription of Antibiotics in Patients With Acute Tonsillitis
Status: COMPLETED
Conditions: Acute Tonsillitis
Interventions: DRUG: Imupret in addition to local NAID|DRUG: Local NAID (Benzydamin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Analgesic Effects of Dronabinol and Smoked Marijuana in Daily Marijuana Smokers
Status: COMPLETED
Conditions: Pain Threshold|Mood
Interventions: DRUG: Placebo capsules|DRUG: Inactive marijuana (0% THC)|DRUG: Low dose Dronabinol|DRUG: High dose Dronabinol|DRUG: Low THC marijuana|DRUG: High THC marijuana
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Examination of Radiographic Progression, Efficacy and Safety of Long-Term Treatment With Infliximab in Patients With Ankylosing Spondylitis
Status: UNKNOWN
Conditions: Ankylosing Spondylitis
Interventions: DRUG: infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Registry to Assess Long-term Outcome in HIV Subjects Who Participated in Phase 2 and 3 Clinical Trials Involving Vicriviroc (Study P04999)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Vicriviroc maleate|DRUG: Vicriviroc maleate|DRUG: Placebo|DRUG: Emtricitabine 200 mg/ tenofovir disoproxil fumarate 300 mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Donor-Alloantigen-Reactive Regulatory T Cell (darTregs) in Liver Transplantation
Status: TERMINATED
Conditions: Liver Transplantation
Interventions: BIOLOGICAL: Anti-Thymocyte Globulin - Rabbit|BIOLOGICAL: darTreg Infusion|DRUG: Everolimus|DRUG: Tacrolimus|DRUG: Mycophenolate mofetil|DRUG: Prednisone|DRUG: Acetaminophen|DRUG: Diphenhydramine|DRUG: Anti-Infective Prophylaxis|PROCEDURE: Leukapheresis|PROCEDURE: Blood draws|PROCEDURE: Liver biopsies|PROCEDURE: Liver transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nanoparticle Albumin-Bound Rapamycin in Treating Patients With Advanced Cancer With mTOR Mutations
Status: COMPLETED
Conditions: Advanced Malignant Neoplasm|Cervical Squamous Cell Carcinoma|Endometrial Carcinoma|Malignant Uterine Neoplasm|Recurrent Bladder Carcinoma|Recurrent Breast Carcinoma|Recurrent Cervical Carcinoma|Recurrent Head and Neck Carcinoma|Recurrent Malignant Neoplasm|Recurrent Ovarian Carcinoma|Recurrent Prostate Carcinoma|Recurrent Renal Cell Carcinoma|Solid Neoplasm|Stage III Bladder Cancer|Stage III Prostate Cancer|Stage III Renal Cell Cancer|Stage IIIA Breast Cancer|Stage IIIA Cervical Cancer|Stage IIIA Ovarian Cancer|Stage IIIB Breast Cancer|Stage IIIB Cervical Cancer|Stage IIIB Ovarian Cancer|Stage IIIC Breast Cancer|Stage IIIC Ovarian Cancer|Stage IV Breast Cancer|Stage IV Ovarian Cancer|Stage IV Prostate Cancer|Stage IV Renal Cell Cancer|Stage IVA Bladder Cancer|Stage IVA Cervical Cancer|Stage IVB Bladder Cancer|Stage IVB Cervical Cancer
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Nanoparticle Albumin-Bound Rapamycin|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Intranasal Steroids in Allergic Rhinitis When Used Alone or in Combination With an Oral Antihistamine (Study P03270)
Status: COMPLETED
Conditions: Rhinitis, Allergic
Interventions: DRUG: Mometasone furoate|DRUG: Mometasone furoate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extended Effects of Cannabis Abstinence on Clinical Symptoms and Cognition in Depression
Status: RECRUITING
Conditions: Cannabis Use|Major Depressive Disorder|Cognitive Impairment
Interventions: BEHAVIORAL: Contingency Reinforcement|BEHAVIORAL: Non-Contingency Reinforcement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Diet and Osteopathy on Quality of Life and Inflammation in Breast Cancer Patients Under Hormonal Therapy
Status: RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: manual treatment with osteopathic techniques and nutritional treatment|OTHER: manual treatment with osteopathic techniques|OTHER: nutritional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Pulmonary Hypertension Web-Based Health Care Program on Symptom Management, Social Support, Activity Tolerance, and Quality of Life in Patients With Pulmonary Hypertension.
Status: RECRUITING
Conditions: Web-based Health Care Program
Interventions: OTHER: Web-based health care program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PK-PD Study of Mycophenolic Acid (CellCept) in Pediatric Kidney Transplant Patients
Status: COMPLETED
Conditions: Kidney Transplant
Interventions: DRUG: CellCept (mycophenolate mofetil)|BEHAVIORAL: Dietary Monitoring|BEHAVIORAL: Drug Diary|PROCEDURE: Blood Sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Head Position on the Intubating Condition Using Fiberoptic Bronchoscopy
Status: COMPLETED
Conditions: Intubation|Posture
Interventions: PROCEDURE: Intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Temporomandibular Joint Condition Post Longstanding Mouth Opening by Rubber Dam
Status: NOT_YET_RECRUITING
Conditions: Temporomandibular Joint Condition Post Longstanding Mouth Opening During Dental Procedure Using Rubber Dam|TMJ Disc Disorder|Osteoarthritis|Myofacial Pain
Interventions: PROCEDURE: Application of a rubber dam during dental treatments for varying durations.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Adjuvant Treatment of Apatinib in Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Apatinib mesylate tablet|RADIATION: Intensity-modulated radiation therapy (IMRT)|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Infusions for Rib Fractures
Status: WITHDRAWN
Conditions: Rib Fracture Multiple|Trauma Chest|Pain, Acute
Interventions: DRUG: Lidocaine infusion|DRUG: Saline infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development of Psychotherapeutic Interventions for Parents Who Lost a Child
Status: ACTIVE_NOT_RECRUITING
Conditions: Parents Who Have Lost a Child
Interventions: BEHAVIORAL: Meaning-Centered Grief Therapy (MCGT)|BEHAVIORAL: Supportive Psychotherapy (SP)|BEHAVIORAL: questionnaires assessments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1 Study of TDM-105795 Topical Solution in Male Subjects With Androgenetic Alopecia (AGA)
Status: COMPLETED
Conditions: Alopecia, Androgenetic
Interventions: DRUG: TDM-105795|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19 First In Human Study to Evaluate Safety, Tolerability, and Pharmacokinetics of EIDD-2801 in Healthy Volunteers
Status: COMPLETED
Conditions: Coronavirus
Interventions: DRUG: EIDD-2801|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A New Experimental Model of Transient and Short-lasting Muscle Pain in Humans Based on Diathermy
Status: COMPLETED
Conditions: Musculoskeletal Pain|Musculoskeletal Injury
Interventions: RADIATION: Short-wave diathermy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 2 Study of Tanezumab in Subjects With Moderate to Severe Pain Due to Schwannomatosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Schwannomatosis|Pain
Interventions: DRUG: Tanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardioprotection by Sevoflurane Preconditioning in Noncardiac Thoracic Surgery
Status: COMPLETED
Conditions: High Sensitive Troponin T Release
Interventions: DRUG: Sevoflurane|DRUG: TIVA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Non-invasive Diagnosis of Invasive Pulmonary Aspergillosis by Use of Biomarkers in Exhaled Breath Condensate
Status: COMPLETED
Conditions: Aspergillosis Pneumonia|Pneumocystis Pneumonia
Interventions: DIAGNOSTIC_TEST: Aspergillus specific proteins in exhaled breath condensate (EBC)|DIAGNOSTIC_TEST: Pneumocystis jirovecii DNA in exhaled breath condensate (EBC)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Shockwaves Therapy and Botulinum Toxin for the Treatment of Spasticity in Patients With Cerebral Palsy. A Cross Over RCT
Status: COMPLETED
Conditions: Spasticity|Cerebral Palsy
Interventions: DEVICE: shock waves|DRUG: Botulinum Toxin Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Doses of vPDT in the Treatment of cCSC
Status: UNKNOWN
Conditions: Central Serous Chorioretinopathy|Therapy, Photodynamic
Interventions: PROCEDURE: 50% dose of photodynamic therapy|PROCEDURE: 70% dose of photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of the Effects of Botulinum Toxin in the Treatment of Provoked Vestibulodynia
Status: COMPLETED
Conditions: Vestibulodynia
Interventions: DRUG: Botulinum Toxin Type A|OTHER: Saline solution|OTHER: Indexes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Study and Compare the Clinical Course and Development of Organ Failure in Severe Acute Hepatitis Without Ascites, Non-cirrhotic and Cirrhotic Patients With Ascites [Acute on Chronic Liver Failure] and Acute Deterioration of Previously Decompensated Cirrhosis.
Status: WITHDRAWN
Conditions: Cirrhosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Regorafenib in Subjects With Metastatic Colorectal Cancer (mCRC) Who Have Progressed After Standard Therapy
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: Regorafenib (Stivarga, BAY73- 4506)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Preloaded System for Renal Arteries in Fenestrated Endografting (MPSRA)
Status: UNKNOWN
Conditions: Juxtarenal Aortic Aneurysm|Thoracoabdominal Aortic Aneurysm|Pararenal Aortic Aneurysm|Aortic Aneurysm, Thoracoabdominal|Dissection Aortic Aneurysm|Penetrating Aortic Ulcer|Endoleak|Pseudoaneurysm
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Clopidogrel and Ticagrelor on Microvascular Dysfunction in ST-Segment Elevation Myocardial Infarction
Status: COMPLETED
Conditions: Non-ST Segment Elevation Myocardial Infarction|ST Segment Elevation Myocardial Infarction
Interventions: DRUG: Clopidogrel|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigation Of The Absorption And Pharmacokinetics Of Multiple Doses Of Two Controlled Release Pregabalin Tablets As Compared To Multiple Doses Of The Immediate Release Pregabalin Capsule In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pregabalin controlled release, 82.5 mg|DRUG: Pregabalin controlled release, 165 mg|DRUG: Pregabalin immediate release, 75mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Oral Moxifloxacin Versus Cefazolin and Oral Probenecid in the Management of Skin and Soft Tissue Infections in the Emergency Department
Status: UNKNOWN
Conditions: Cellulitis
Interventions: DRUG: Cefazolin and Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Nasal Non Invasive Ventilation in Management of Neonates With Respiratory Distress Using Lung Ultrasound
Status: NOT_YET_RECRUITING
Conditions: Preterm|Ventilator Lung; Newborn
Interventions: DEVICE: Nasal humidified heated high flow cannula (NHHHC)|DEVICE: Nasal intermittent positive pressure ventilation (NIPPV)|DEVICE: Nasal continuous positive airway pressure NCPAP|DEVICE: lung ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Abnormal Respiratory Mechanics and Assisted Mechanical Ventilation on Neuro-regulation of Respiration
Status: TERMINATED
Conditions: Neuroregulation of Breathing
Interventions: PROCEDURE: Records of EADI derived parameters
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparions the Effect of Different Treatment Modalities on Chronic Plantar Fasiitis
Status: COMPLETED
Conditions: Plantar Fasciitis, Chronic
Interventions: DEVICE: ESWT, Graston Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Cuff Pressure of an Endotracheal Tube After Supine-to-lateral Position Change
Status: UNKNOWN
Conditions: Intubation|Pain|Pharyngitis|Hoarseness|Cough
Interventions: DEVICE: Barrel|DEVICE: Tapered
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Compare Outcomes of CPR Between the Video-laryngoscopy (VL) Users and the Direct-laryngoscopy (DL) Users
Status: COMPLETED
Conditions: Cardiopulmonary Arrest
Interventions: PROCEDURE: Endotracheal Intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraintestinal Extended Biliary Stents Preventing Duodenobiliary Reflux in Patients With Biliary Stricture
Status: UNKNOWN
Conditions: Bile Duct Stricture
Interventions: PROCEDURE: intraintestinal extended biliary stents|PROCEDURE: ordinary plastic biliary stents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: High Flow Therapy (HFT) to Treat Respiratory Insufficiency in Chronic Obstructive Pulmonary Disease (COPD)
Status: WITHDRAWN
Conditions: Pulmonary Disease, Chronic Obstructive|Respiratory Insufficiency
Interventions: DEVICE: Vapotherm High Flow Therapy|DEVICE: Non-invasive positive pressure ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Application of Diode Laser and Different Remineralizing Agents on White Spot Lesions
Status: COMPLETED
Conditions: White Spot Lesion of Tooth
Interventions: PROCEDURE: Remin Pro|PROCEDURE: X Pur Remin|PROCEDURE: Fluoride varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PMCF Study on Monofocal Toric IOL (PODEYE TORIC) in Spain
Status: COMPLETED
Conditions: Cataract|Lens Opacities|Astigmatism
Interventions: DEVICE: IOL implantation experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Seroquel Extended Release (XR) for the Management of Borderline Personality Disorder (BPD)
Status: COMPLETED
Conditions: Borderline Personality Disorder
Interventions: DRUG: quetiapine extended-release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Lumacaftor and Ivacaftor Combination Therapy in Subjects 12 Years and Older With Advanced Lung Disease
Status: COMPLETED
Conditions: Cystic Fibrosis|Advanced Lung Disease
Interventions: DRUG: Lumacaftor|DRUG: Ivacaftor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Healthy Eating Choices for Life Program
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Standard Behavioral Weight Loss Intervention|BEHAVIORAL: Dietary Goal: Reduction in Energy Density of Dietary Intake|BEHAVIORAL: Dietary Goal: Reduction of Energy Intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Neuroleptic Induced Acute Akathisia With Trazodone
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Placebo|DRUG: Trazodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics as Adjunct to Nonsurgical Periodontal Treatment
Status: COMPLETED
Conditions: Periodontitis
Interventions: DIETARY_SUPPLEMENT: Probiotic lozenges|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics in the Prevention of Complications After Colorectal Surgery
Status: COMPLETED
Conditions: Postoperative Complications
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bimanual Uterine Compression to Reduce Blood Loss and Prevent Postpartum Haemorrhage After Vaginal Delivery
Status: UNKNOWN
Conditions: Postpartum Haemorrhage
Interventions: PROCEDURE: bimanual uterine compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Physiotherapy Intervention With Flossing Conditioned by Verbal Suggestion About Ankle Functionality in Amateur Runners
Status: WITHDRAWN
Conditions: Running
Interventions: OTHER: Positive expectation|OTHER: Neutral expectation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Dry Heat and Dry Cold Application on Blood Sampling in Children
Status: COMPLETED
Conditions: School Age Children|Blood|Procedural Pain|Procedural Anxiety|Fear
Interventions: OTHER: Dry heat application|OTHER: Dry cold application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pregabalin Peripheral Neuropathic Pain Study
Status: COMPLETED
Conditions: Diabetic Neuropathies|Neuralgia
Interventions: DRUG: pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Outcomes Under a Standardized Treatment Protocol in Patients Suffered Substance Abuse Related Voiding Dysfunction
Status: RECRUITING
Conditions: Voiding Dysfunction|Substance Abuse
Interventions: DRUG: First line treatment: oral NSAID and anticholinergic agents|DRUG: Second line treatment: additional treatment for pain control|DRUG: Third line treatment: A course of intravesical hyaluronate will be given.|PROCEDURE: Fourth line treatment: surgical intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Smoking, Age and Body Size on Pharmacokinetics, Safety and Tolerability on Tasimelteon in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Tasimelteon
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Modified Sham Feeding With Orlistat in Overweight and Obese Subjects
Status: WITHDRAWN
Conditions: Overweight
Interventions: DRUG: Placebo|DRUG: Orlistat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Safety and Pharmacokinetics of HBI-002, an Oral Carbon Monoxide Therapeutic, in Healthy Volunteers
Status: COMPLETED
Conditions: Anemia, Sickle Cell
Interventions: DRUG: HBI-002
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Efficacy and Pharmacokinetics of Teduglutide in Japanese Subjects With PN-dependent Short Bowel Syndrome (SBS)
Status: COMPLETED
Conditions: Short Bowel Syndrome
Interventions: DRUG: Teduglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gait Analysis in Neurological Disease
Status: RECRUITING
Conditions: Parkinson's Disease|Parkinsonian Disorders|Atypical Parkinson Disease|Progressive Supranuclear Palsy|Multiple System Atrophy|Corticobasal Degeneration|Gait, Frontal|Huntington Disease
Interventions: DRUG: Anti-Parkinson medication|DEVICE: Deep Brain Stimulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Loss of Autonomy in the Elderly: Relationships Between Gut Microbiota Diversity, Nutrition and Cognitive and Sensory-motor Disturbances in "Small Eaters" and "Non Small Eaters"
Status: RECRUITING
Conditions: Elderly Small Eater
Interventions: BIOLOGICAL: Fecal and blood sampling and collection of nutritional, cognitive and sensorimotor data|OTHER: Body Mass Index (BMI)|OTHER: 24-hour food and beverage record|OTHER: Mini Nutritional assessment (MNA)|OTHER: Measurement of muscle mass by bioelectrical impedance analysis (except for participants with a pacemaker)|OTHER: Measurement of sensorimotor functions|OTHER: Measurement of cognitive functions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose Ranging Study to Evaluate Immunogenicity and Safety of Adjuvanted or Non-adjuvanted Cell Culture-derived H5N1 Influenza Vaccine in Young Adults (18-40 Years Old)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Cell Culture-Derived H5N1 Subunit Influenza Vaccine, 3.75_0%MF59|BIOLOGICAL: Cell Culture-Derived H5N1 Subunit Influenza Vaccine, 3.75_25%MF59|BIOLOGICAL: Cell Culture-Derived H5N1 Subunit Influenza Vaccine, 3.75_50%MF59|BIOLOGICAL: Cell Culture-Derived H5N1 Subunit Influenza Vaccine, 3.75_100%MF59|BIOLOGICAL: Cell Culture-Derived H5N1 Subunit Influenza Vaccine, 7.5_0%MF59|BIOLOGICAL: Cell Culture-Derived H5N1 Subunit Influenza Vaccine, 7.5_25%MF59|BIOLOGICAL: Cell Culture-Derived H5N1 Subunit Influenza Vaccine, 7.5_50%MF59|BIOLOGICAL: Cell Culture-Derived H5N1 Subunit Influenza Vaccine, 7.5_100%MF59|BIOLOGICAL: Cell Culture-Derived H5N1 Subunit Influenza Vaccine, 15_0%MF59|BIOLOGICAL: Cell Culture-Derived H5N1 Subunit Influenza Vaccine, 15_25%MF59|BIOLOGICAL: Cell Culture-Derived H5N1 Subunit Influenza Vaccine, 15_50%MF59|BIOLOGICAL: Cell Culture-Derived H5N1 Subunit Influenza Vaccine, 15_100%MF59
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Urogynecological and Sexual Functions After Vecchietti Operation
Status: COMPLETED
Conditions: Mayer-Rokitansky-Kuster Syndrome
Interventions: PROCEDURE: laparoscopic Vecchietti vaginoplasty|DIAGNOSTIC_TEST: FSFI questionnaire|DIAGNOSTIC_TEST: UDI-6 questionnaire|DIAGNOSTIC_TEST: IIQ-7 questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Infant Nutrition and Risk of Celiac Disease
Status: TERMINATED
Conditions: Celiac Disease|Infant Nutrition
Interventions: DIETARY_SUPPLEMENT: Gluten|DIETARY_SUPPLEMENT: Gluten free diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Tailored Mediterranean Lifestyle Education in Participants With Subjective Cognitive Impairment
Status: COMPLETED
Conditions: Subjective Cognitive Impairment
Interventions: BEHAVIORAL: "THINK-MED" resource (baseline)|BEHAVIORAL: "THINK-MED" resource (staged)|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Procedural Efficiency and Organisational Impact of Rhino Laryngoscopes Procedures in Consults
Status: UNKNOWN
Conditions: Laryngeal Disease
Interventions: DEVICE: Ambu® aScope™ 4 Rhinolaryngo|DEVICE: Conventional reusable rhinolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Brain Stimulation and Cognitive Processing in Depression
Status: COMPLETED
Conditions: Unipolar Major Depressive Disorder
Interventions: DEVICE: Transcranial direct current stimulation (tDCS)|BEHAVIORAL: Cognitive Behavioural Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Hypericum Perforatum Oil on Promoting Skin Recovery in Different Human Skin Damage Models
Status: COMPLETED
Conditions: Skin Recovery in Different Human Skin Damage Models
Interventions: OTHER: Hypericum perforatum oil|OTHER: Placebo|PROCEDURE: SLS induced irritation|PROCEDURE: Tape-stripping|PROCEDURE: UV radiation|PROCEDURE: Intact skin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Low-dose Intracoronary Thrombolytic Therapy in STEMI (Heart Attack) Patients.
Status: RECRUITING
Conditions: STEMI|Elevated IMR (>32)
Interventions: DRUG: Tenecteplase (1/3 systemic weight based dose)|OTHER: Sterile water for injection (WFI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Radium-223 in Biochemically Recurrent Prostate Cancer
Status: RECRUITING
Conditions: Biochemical Recurrent Prostate Cancer
Interventions: DRUG: Radium-223|DRUG: 18F Sodium Fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Anesthetic Nebulization and Instillation for Pain Control After Laparoscopic Surgery
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: DRUG: Ropivacaine 60 mg|DRUG: Ropivacaine 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Long Term Safety Study to Test the Combination of Aliskiren/ Amlodipine / Hydrochlorothiazide in Participants With Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Aliskiren|DRUG: Amlodipine|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study to Evaluate Safety, Reactogenicity, and Immunogenicity of mRNA-1345 in Healthy Adults and in Children Who Are Respiratory Syncytial Virus (RSV)-Seropositive
Status: COMPLETED
Conditions: Respiratory Syncytial Virus
Interventions: BIOLOGICAL: mRNA-1345|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants
Status: RECRUITING
Conditions: Lupus Nephritis
Interventions: DRUG: Obinutuzumab|DRUG: Placebo|DRUG: Mycophenolate Mofetil|DRUG: Acetaminophen/paracetamol|DRUG: Diphenhydramine hydrochloride (HCl)|DRUG: Methylprednisolone|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Compression Gloves to Reduce Albumin-binding Paclitaxel Induced Peripheral Sensory and Motor Neurotoxicity (REMAINING)
Status: UNKNOWN
Conditions: Peripheral Neuropathy
Interventions: DEVICE: Compression gloves
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multicenter, Open-label Clinical Trial to Evaluate the Efficacy and Safety of Once Daily Mirvaso® Gel in Patients With Chronic Persistent Vascular Facial Erythema.
Status: COMPLETED
Conditions: Chronic Persistent Vascular Facial Erythema
Interventions: DRUG: brimonidine tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Oral Progesterone and Vaginal Progesterone After Tocolytic Therapy in Threatened Preterm Labor
Status: COMPLETED
Conditions: Preterm Delivery
Interventions: DRUG: dydrogesterone|DRUG: Micronized progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Chemotherapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Persistent Ovarian Epithelial Cancer
Status: TERMINATED
Conditions: Ovarian Cancer
Interventions: DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: mitoxantrone hydrochloride|DRUG: paclitaxel|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Post Transjugular Intrahepatic Portosystemic Shunt (Tips) Albumine Infusion to Prevent Hepatic Encephalopathy
Status: COMPLETED
Conditions: Hepatic Encephalopathy
Interventions: DRUG: Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Qingre Huashi Granules Combined the Modified Dual Therapy for Helicobacter Pylori Infection
Status: RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Qingre Huashi Granules combined the modified dual therapy|DRUG: Bismuth containing quadruple therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comprehensive Study to Isolate Tumor-initiating Cells From Human Epithelial Malignancies
Status: WITHDRAWN
Conditions: Bladder Cancer|Skin Cancers|Bladder (Urothelial, Transitional Cell) Cancer|Bladder (Urothelial, Transitional Cell) Cancer Resectable (Pre-Cystectomy)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Imatinib Mesylate and Zoledronic Acid in Patients With Chronic Myeloid Leukaemia in Cytogenetic Response Without Molecular Response
Status: TERMINATED
Conditions: Myeloid Leukemia, Chronic
Interventions: DRUG: Glivec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Direct HIS/LBB Pacing as an Alternative to Biventricular Pacing in Patients With HFrEF and a Typical LBBB.
Status: RECRUITING
Conditions: Heart Failure|Left Bundle-Branch Block
Interventions: DEVICE: HIS/LBB pacing|DEVICE: LV pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iron Supplementation and Eccentric Exercise
Status: COMPLETED
Conditions: Muscle Damage|Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: Iron supplement Resoferon Ferrous Sulfate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Efficacy and Safety of Peginterferon Alfa-2b and Ribavirin Therapy in Subjects With Type C Compensated Liver Cirrhosis (Study P05116)
Status: COMPLETED
Conditions: Hepatitis C, Chronic|Liver Cirrhosis
Interventions: BIOLOGICAL: Peginterferon alfa-2b|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Establishment of Abbreviated Pancreatobiliary MRI Protocol
Status: COMPLETED
Conditions: Pancreas Cyst|Intraductal Papillary Mucinous Neoplasm
Interventions: DIAGNOSTIC_TEST: Abbreviated PB MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: 18F-fluciclovine PET/MRI Imaging for the Detection of Tumor Recurrence After Radiation Injury to the Brain
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Intracranial Malignant Neoplasm|Recurrent Intracranial Neoplasm
Interventions: RADIATION: Dynamic Contrast-Enhanced Magnetic Resonance Imaging with Positron Emission Tomography|OTHER: Fluciclovine F18
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of a Booster Course of Antenatal Steroids on Neonatal Outcome in Patients With Premature Rupture of the Membranes
Status: COMPLETED
Conditions: Premature Birth
Interventions: DRUG: Betamethasone - ACTIVE|OTHER: Normal Saline - PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nalmefene Gambling Study: Study of Nalmefene HCl in the Treatment of Pathological Gambling
Status: COMPLETED
Conditions: Pathological Gambling
Interventions: DRUG: nalmefene HCl|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Treatment of Adhesive Small Bowel Obstruction
Status: RECRUITING
Conditions: Adhesive Small Bowel Obstruction
Interventions: DRUG: Gastrografin|DRUG: Saline|PROCEDURE: SBO Treatment Without NG Tubes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow Up of High Risk Hodgkin Lymphoma in First Complete Remission
Status: COMPLETED
Conditions: Hodgkin Lymphoma|High Risk|Relapse
Interventions: DIAGNOSTIC_TEST: Standard cohort: Clinical lab follow-up|DIAGNOSTIC_TEST: Imaging cohort: integrated imaging follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Deconditioning in Transplant
Status: COMPLETED
Conditions: Hematopoietic and Stem Cell Transplant
Interventions: OTHER: General Health Module-Baseline Adolescent-Self Report (13-18 years)|OTHER: General Health Module-Follow Up Adolescent-Self Report (13-18 years)|OTHER: General Health Module-Baseline Parent Report-Adolescent (13-18 years)|OTHER: General Health Module-Follow Up Parent Report-Adolescent (13-18 years)|OTHER: General Health Module-Baseline Parent Report-School Age (5-12 years)|OTHER: General Health Module-Follow Up Parent Report-School Age (5-12 years)|OTHER: Demographic Data Form|OTHER: SCT Daily Activity Log|OTHER: The Functional Independence Measure for Children|OTHER: Manual Muscle Testing|OTHER: 3-Minute Step Test|OTHER: HSCT Module-Follow Up Adolescent-Self Report (13-18 years)|OTHER: HSCT Module-Follow Child-Self Report (5-12 years)|OTHER: HSCT Module-Follow Up Parent Report-adolescent (13-18 years)|OTHER: HSCT Module-Follow Up Parent Report-School Age (5-12 years)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Focus on Vaginal Examination Experience and Pain Level: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Birth, First|Experience, Life|Pain
Interventions: OTHER: Primiparous pregnant women who will undergo vaginal examination by focusing on visual traces
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pre-surgical Antisepsis Using an Alcoholic Solution of Chlorhexidine Digluconate and Potassium Sorbate
Status: COMPLETED
Conditions: Antisepsis
Interventions: DRUG: Hand antisepsis with Clorhexidine and solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of the Optic Disc Parameters
Status: COMPLETED
Conditions: Normal Healthy Subjects With No Known Ocular Diseases|Glaucomatous Eyes|Eyes With Retinal Diseases
Interventions: DEVICE: Maestro|DEVICE: iVue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: KDR2-2 Suspension Eyedrop in the Treatment of Neovascular Glaucoma (KDR-NVG) Trial
Status: UNKNOWN
Conditions: Neovascular Glaucoma|Neovascularization
Interventions: DRUG: 4mg/ml KDR2-2 suspension eyedrop|DRUG: 16mg/ml KDR2-2 suspension eyedrop
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alisertib in Treating Patients With Myelofibrosis or Relapsed or Refractory Acute Megakaryoblastic Leukemia
Status: UNKNOWN
Conditions: Acute Megakaryoblastic Leukemia|Myelofibrosis|Primary Myelofibrosis
Interventions: DRUG: Alisertib|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Ceftaroline in Subjects With Staphylococcus Aureus Bacteremia or With Persistent Methicillin-Resistant Staphylococcus Aureus Bacteremia
Status: COMPLETED
Conditions: Staphylococcus Aureus Bacteremia|Methicillin-resistant Staphylococcus Aureus (MRSA) Bacteremia
Interventions: DRUG: Ceftaroline fosamil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of PROCRIT (Epoetin Alfa) in Patients Undergoing Elective Major Abdominal and/or Pelvic Surgery
Status: TERMINATED
Conditions: Hemostasis, Surgical
Interventions: DRUG: Epoetin alfa|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Clindamycin Resistance Antibiotic Genes Among Staphylococcus Isolates by Using Real Time PCR
Status: UNKNOWN
Conditions: Staphylococcus Isolates
Interventions: GENETIC: Detection of Clinclidamycin Resistance Antibiotic Genes among Staphylococcus Isolates by Using Real Time PCR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparing the Efficacy of Tacrolimus and Mycophenolate Mofetil for the Initial Therapy of Active Lupus Nephritis
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: DRUG: tacrolimus|DRUG: mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT