pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: MonaLisa Laser Intervention for Post-Menopausal Breast Cancer Patients: A SHE CAN Study
Status: WITHDRAWN
Conditions: Breast Cancer Female|Genitourinary Syndrome of Menopause
Interventions: DEVICE: Microablative Fractional CO2 Laser Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab Therapy Untreated Unresectable Liver Metastases From Colorectal Cancer
Status: UNKNOWN
Conditions: Liver Metastases|Colorectal Cancer
Interventions: DRUG: bevacizumab plus chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Adjuvanted Reduced Dose Inactivated Polio Vaccine in 2, 4, 6 Months of Age
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: IPV-Al SSI|BIOLOGICAL: IPV SSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Influence of Role-expectancy on Patient Reported Outcomes Among Patients With Migraine: a Randomized Clinical Trial
Status: COMPLETED
Conditions: Role-expectancy on Patient Reported Outcomes
Interventions: BEHAVIORAL: cover story
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Safety of a New Oxime, MMB4 DIMETHANESULFONATE (DMS)
Status: COMPLETED
Conditions: Safety and Efficacy
Interventions: DRUG: MMB4 DMS|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Smartphone Video-assisted Advanced Life Support of Patients With Out-of-hospital Cardiac Arrest by EMS Under Physician Direction
Status: COMPLETED
Conditions: Out-of-Hospital Cardiac Arrest
Interventions: OTHER: Smartphone video-assisted ALS(advanced life support)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Cervical Fusion With DTRAX® Cervical Cage With DTRAX Bone Screw
Status: WITHDRAWN
Conditions: Cervical Radiculopathy
Interventions: DEVICE: DTRAX® Cervical Cage with DTRAX Bone Screw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-Fluoromisonidazole and Fludeoxyglucose F 18 PET/CT Patients With Soft Tissue Sarcoma
Status: TERMINATED
Conditions: Recurrent Adult Soft Tissue Sarcoma|Stage I Adult Soft Tissue Sarcoma|Stage II Adult Soft Tissue Sarcoma|Stage III Adult Soft Tissue Sarcoma|Stage IV Adult Soft Tissue Sarcoma
Interventions: RADIATION: fludeoxyglucose F 18|OTHER: 18F-fluoromisonidazole|PROCEDURE: positron emission tomography|PROCEDURE: computed tomography|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Epinephrine Infusion for Prophylaxis Against Maternal Hypotension During Caesarean Section
Status: TERMINATED
Conditions: Post-spinal Hypotension|Cesarean Section
Interventions: DRUG: Epinephrin 0.03|DRUG: Epinephrin 0.05|DRUG: Epinephrin 0.07
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Modeling and Treating the Pathophysiology of Demyelination in Multiple Sclerosis
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: DRUG: ACTHAR|DRUG: ACTHAR|DRUG: ACTHAR|DRUG: ACTHAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of a Multi-component Individualized Telephone-based Support Intervention for Adult-child Caregivers Caring for Parents With Dementia
Status: WITHDRAWN
Conditions: Dementia
Interventions: BEHAVIORAL: HEART|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: RhBMP-2 in Intrabony Defects - A Randomized Controlled Trial
Status: COMPLETED
Conditions: Periodontitis
Interventions: DRUG: BMP-2|PROCEDURE: PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare the Efficacy of Drugs in Combination for Treating Irritable Bowel Syndrome Associated With Diarrhea
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Diarrhea
Interventions: DRUG: Rifaximin 550 MG|DRUG: Mebeverine 135 MG|DRUG: Psyllium Husk|DRUG: Amitriptyline Hydrochloride 25 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Study To Investigate The Effects Of Fesoterodine And Solifenacin On Gastrointestinal Transit
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: fesoterodine fumarate|DRUG: placebo|DRUG: solifenacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Performance Study of the Optimum Transcatheter Aortic Valve
Status: RECRUITING
Conditions: Severe Aortic Stenosis
Interventions: DEVICE: Transcatheter Aortic Valve (TAV) Implantation With The Optimum TAV System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Phase I Study to Compare NP101(Sumatriptan Iontophoretic Transdermal Patch) With Three Formulations of Imitrex®
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Sumatriptan succinate|DRUG: Sumatriptan succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atrial Fibrillation Detected by Continuous ECG Monitoring
Status: COMPLETED
Conditions: Atrial Fibrillation|Stroke|Hypertension|Diabetes
Interventions: DEVICE: Implantable loop recorder (Medtronic Reveal LINQ(TM))
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Training Study for Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: BEHAVIORAL: Self-Regulated Exercise with Telephone Reinforcement|BEHAVIORAL: Standard Treatment|BEHAVIORAL: Qualitative Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Outcome and Complications Encountered in Flapless Surgery and Immediate Loading Versus the Classical Surgical Approach and Loading After 6-8 Weeks in the Posterior Maxilla
Status: COMPLETED
Conditions: Dental Implants
Interventions: PROCEDURE: Placement of implants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Music Therapy on Intraoperative Patient Comfort During Cataract Surgery With Topic Anesthesia
Status: UNKNOWN
Conditions: Cataract|Anxiety
Interventions: DEVICE: MusicCare® device|DEVICE: Headphones with noise reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Usability Study of iTEAR100 For Combined EyeLid Microblepharoexfoliation and Neurostimulation
Status: RECRUITING
Conditions: MicroBlepharoexfoliation, NuLids, iTEAR100, iLIDS100, Blepharitis, Dry Eye Syndrome
Interventions: DEVICE: iLIDS100
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic PreConditioning (RIPC)
Status: WITHDRAWN
Conditions: Unruptured Cerebral Aneurysm
Interventions: DEVICE: Standard Manual Aneroid Sphygmomanometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Examination of the Efficacy of a Self-Determination Theory and Motivational Interviewing Exercise Intervention
Status: COMPLETED
Conditions: Exercise Promotion
Interventions: BEHAVIORAL: MI and SDT Exercise Group|BEHAVIORAL: Non-MI and SDT Exercise Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Crossover Study to Evaluate the Effect of JNJ-54452840 on Pharmacodynamics of Metoprolol Tartrate Immediate-Release in Healthy Participants
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: Metoprolol tartrate immediate-release (metoprolol IR)|DRUG: JNJ-54452840|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Sedation During Cervical Dilator Placement
Status: COMPLETED
Conditions: Oral Sedation and Cervical Dilator Pain
Interventions: DRUG: Oxycodone and Lorazepam (Active Comparator)|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Pantoprazole Treatment in Patients With Functional Dyspepsia
Status: UNKNOWN
Conditions: Nonulcer Dyspepsia
Interventions: DRUG: Pantoprazol|DRUG: Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Repeated Transcranial Magnetic Stimulation on Off-line Resting Electroencephalographic Signal in Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DEVICE: rTMS real
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Safety, Tolerability and Effect of Nexagon™ Applied to the Eye After PRK Laser Eye Surgery for Nearsightedness
Status: COMPLETED
Conditions: Corneal re-Epithelialization
Interventions: DRUG: Nexagon™ or Nexagon™ vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Intravenous and Oral Isavuconazonium Sulfate in Pediatric Patients
Status: COMPLETED
Conditions: Hematological Malignancy
Interventions: DRUG: isavuconazonium sulfate - intravenous|DRUG: isavuconazonium sulfate - oral
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Genetic Predictors of the Response to Selective Serotonin Re-uptake Inhibitors (SSRI) Treatment
Status: COMPLETED
Conditions: Major Depression
Interventions: DRUG: escitalopram|DRUG: bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptive Nutrition and Exercise Weight Loss (A-NEW) Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Overweight or Obesity
Interventions: DRUG: Contrave|BEHAVIORAL: Behavioral Weight Loss
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Ethyl Icosapentate in Patients With Severe Hypertriglyceridemia
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DRUG: Placebo|DRUG: Ethyl Icosapentate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of EN3835 in the Treatment of EFP (Cellulite) in Women
Status: COMPLETED
Conditions: Edematous Fibrosclerotic Panniculopathy (Cellulite)
Interventions: BIOLOGICAL: EN3835|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin for Reduction of 28-day Mortality in COVID-19: RCT
Status: UNKNOWN
Conditions: Covid19|SARS-CoV2 Infection|COVID-19 Pneumonia
Interventions: DRUG: Atorvastatin 40 Mg Oral Tablet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: iCare for Cancer Patients
Status: TERMINATED
Conditions: Myelodysplastic Syndromes|Acute Myeloid Leukemia|Acute Myelogenous Leukemia|Acute Lymphoid Leukemia|Leukemia, Acute Lymphoblastic|Multiple Myeloma|Myelofibrosis
Interventions: GENETIC: Molecular diagnostic testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Turmeric for Memory Impairment and Cognition
Status: COMPLETED
Conditions: Cognitive Change|Mood|Stress
Interventions: DIETARY_SUPPLEMENT: Turmipure Gold®|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of 2 Treatment Regimens for Eradication of P Aeruginosa Infection in Children With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: oral ciprofloxacin plus inhaled colistin|DRUG: TOBI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Participatory Organizational Intervention for Improved Use of Assistive Devices for Patient Handling
Status: COMPLETED
Conditions: Musculoskeletal Disorders|Occupational Injuries
Interventions: BEHAVIORAL: Participatory Organizational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety of a Boost (CXB or EBRT) in Combination With Neoadjuvant Chemoradiotherapy for Early Rectal Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Rectal Neoplasms
Interventions: RADIATION: 3D conformal EBRT|DEVICE: Contact X-ray brachytherapy 50 kV|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whey vs Casein to Combat Post-inflammatory Protein and Muscle Waste in Acute Disease
Status: COMPLETED
Conditions: Muscle Protein Synthesis|Endotoxemia|Nutrition|Milk Protein|Metabolism|Whey|Casein
Interventions: DIETARY_SUPPLEMENT: Casein|DIETARY_SUPPLEMENT: Whey|DIETARY_SUPPLEMENT: Leucine-enriched whey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: SLEEP ON Your SIDE (SOS) Study
Status: TERMINATED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: NightBalance Sleep Position Trainer (SPT)|DEVICE: Automatic Positive Airway Pressure (APAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LOC387715/HTRA1 Variants in Polypoidal Choroidal Vasculopathy in a Korean Population
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: GENETIC: LOC387715/HTRA1 genotyping
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Attentional Capacity and Working Memory in Coronary Artery Disease Patients: Impact of the Presence of a Sleep Apnea Syndrome and Chronic Effects of Treatment With CPAP
Status: TERMINATED
Conditions: Obstructive Sleep Apnea|Acute Coronary Syndrome
Interventions: DEVICE: CPAP treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Single Dose Crossover Study of Patient Preference for Unscented Nasonex® Nasal Spray Versus Scented Flonase® Nasal Spray (Study P04207)
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Mometasone Furoate Nasal Spray|DRUG: fluticasone nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Nexagon for Persistent Corneal Epithelial Defects
Status: TERMINATED
Conditions: Persistent Corneal Epithelial Defects
Interventions: DRUG: Nexagon|DRUG: Vehicle only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET/CT Quantitative Assessment of Myocardial Blood Flow Changes in Oncologic Patients Receiving Checkpoint Inhibitor Therapy
Status: COMPLETED
Conditions: Cancer
Interventions: DIAGNOSTIC_TEST: PET/CT|DRUG: radioactive drug (tracer)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Newly Diagnosed High Risk Acute Lymphoblastic Leukemia in Children
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia|Child
Interventions: DRUG: high dose methotrexate|DRUG: Intrathecal triple chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Order for Rapid Sequence Intubation
Status: COMPLETED
Conditions: Acute Respiratory Failure
Interventions: OTHER: Rapid sequence intubation: sedative first|OTHER: Rapid sequence intubation: paralytic first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Assessment Of Healing After Periodontal Flap Surgery With And Without The Use Of Placental Extracts
Status: COMPLETED
Conditions: Periodontal Diseases|Periodontal Pocket|Periodontitis
Interventions: BIOLOGICAL: delivery of placentrex gel after open flap debridement|PROCEDURE: Open Flap Debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Educational Nursing Intervention Among Patients With Colorectal Cancer During Chemotherapy
Status: COMPLETED
Conditions: Patient Empowerment|Patient Activation|Self Care|Cancer of Colon|Cancer of Rectum
Interventions: BEHAVIORAL: Educational nursing intervention on nutrition intake related chemotherapy induced side-effects' self-care among the patients with colorectal cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Efficacy and Safety Study of Golimumab in Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Golimumab 100 mg|DRUG: Golimumab 50 mg|DRUG: Methotrexate|DRUG: Placebo injection|DRUG: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Tolerability of Oligosaccharide Supplementation in Patients With Crohn's Disease
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Moderate Oligosaccharide Group|DIETARY_SUPPLEMENT: High Oligosaccharide Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: An HIV Vaccine Trial in Individuals Who Started ART During Primary or Chronic Infection
Status: TERMINATED
Conditions: HIV-1-infection
Interventions: BIOLOGICAL: GTU-MultiHIV B-clade vaccine + MVA HIV-B HIV vaccine|BIOLOGICAL: GTU-MultiHIV B-clade vaccine + MVA HIV-B HIV vaccine+ Vedolizumab|DRUG: Vedolizumab 300 MG [Entyvio]|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy of ICL670 vs. Deferoxamine in Beta-thalassemia Patients With Iron Overload Due to Blood Transfusions
Status: COMPLETED
Conditions: Beta-Thalassemia
Interventions: DRUG: ICL670|DRUG: deferoxamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Autologous Human Schwann Cell (ahSC) Augmentation in Severe Peripheral Nerve Injury (PNI)
Status: RECRUITING
Conditions: Peripheral Nerve Injury
Interventions: BIOLOGICAL: Autologous Human Schwann Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Affective Prosody Recognition and Auditory Intervention for Children With Autism Spectrum Disorders (ASD)
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Auditory Training|BEHAVIORAL: Non-auditory training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic in Treatment of Adult Patients With Drug-resistant Epilepsy
Status: COMPLETED
Conditions: Epilepsy|Treatment
Interventions: DRUG: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Candy and Honey in Decreasing Salivary Gland Damage Following Radioiodine Therapy for Thyroid Cancer
Status: COMPLETED
Conditions: Thyroid Cancer
Interventions: DIETARY_SUPPLEMENT: thymus honey mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: OPTIMA-TBI Pilot Study
Status: TERMINATED
Conditions: Mild Traumatic Brain Injury
Interventions: DRUG: Omega-3 Polyunsaturated Fatty Acids (Fish Oil 1000 mg (contains 500 mg DHA & 100 mg EPA)) or placebo capsules.|DRUG: Placebo - Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of Two Chiropractic Treatment Protocols for Knee Pain Due to Patellofemoral Pain Syndrome
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: PROCEDURE: chiropractic manipulative therapy|PROCEDURE: knee exercises|PROCEDURE: Graston Instrument Soft Tissue Mobilization (GISTM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Tislelizumab as Adjuvant Therapy for Patients With Stage Ⅱ and Stage Ⅲ Colon Cancer and dMMR/MSI.
Status: NOT_YET_RECRUITING
Conditions: Colon Cancer
Interventions: DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Single Use Point of Care Device for the Diagnosis of Respiratory Pathogens
Status: UNKNOWN
Conditions: Human Influenza|Respiratory Syncytial Virus Infections|Rhinoviral Infections|Enterovirus Infections|Metapneumovirus Infection|Parainfluenzae Viral Infections
Interventions: DIAGNOSTIC_TEST: Point of care testing of respiratory viruses.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial of Dental Implants in Titanium-zirconium Alloy
Status: UNKNOWN
Conditions: Endosseous Dental Implant Failure
Interventions: PROCEDURE: Titanium-zirconium|PROCEDURE: Titanium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab, Nivolumab, Tocilizumab and Radiation in Pretreated Patients With Advanced Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|DRUG: Tocilizumab|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of the Use of Zinc in the Prevention of Oral Mucositis in Pediatric Patients With Lymphoblastic Acute Leukemia.
Status: TERMINATED
Conditions: Oral Mucositis
Interventions: DRUG: Zinc Sulfate 50 Mg Tab|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Independent Studies of Dextromethorphan and of Donepezil Hydrochloride for Rett Syndrome
Status: UNKNOWN
Conditions: Rett Syndrome
Interventions: DRUG: dextromethorphan|DRUG: donepezil hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing PTCy Dose and Timing
Status: RECRUITING
Conditions: Graft Versus Host Disease|Hematologic Neoplasms
Interventions: DRUG: Busulfan|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Mycophenolate Mofetil|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parathyroidectomy vs Cinacalcet in the Treatment of Secondary Hyperparathyroidism Post Renal Transplantation
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism
Interventions: PROCEDURE: Subtotal parathyroidectomy|DRUG: Cinacalcet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Propofol vs Sevoflurane in Cyanotic Congenital Heart Disease
Status: COMPLETED
Conditions: Cyanotic Congenital Heart Disease|Pediatric HD
Interventions: DRUG: Propofol|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Compare Pharmacokinetics, Safety, and Immunogenicity of HLX11 vs. Perjeta in Healthy Chinese Male Subjects
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: HLX11|DRUG: CN-Perjeta(Pertuzumab)|DRUG: EU-Perjeta(Pertuzumab)|DRUG: US-Perjeta(Pertuzumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stability of the Knee Joint After Single and Double Bundle Anterior Cruciate Ligament Reconstruction
Status: COMPLETED
Conditions: Rupture of Anterior Cruciate Ligament
Interventions: PROCEDURE: 'biomechanic of the knee'
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intravenous Exenatide (Byetta) During Surgery
Status: COMPLETED
Conditions: Euglycemia|Hypoglycemia|Hyperglycemia
Interventions: DRUG: Exenatide 0.27 ng/kg/min|DRUG: Exenatide 0.41 ng/kg/min|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Shifting Brain Excitation-Inhibition Balance in Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: PLC|DRUG: CBD|DRUG: CBDV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fed-Fast Crossover Study to Assess the Effect of Food With CTx-1301 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers in Fed and Fasted State
Interventions: DRUG: Dexmethylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Immunogenicity and Safety Study of Tetanus, Diphtheria and Acellular Pertussis Vaccine Booster
Status: UNKNOWN
Conditions: Tetanus|Diphtheria|Pertussis
Interventions: BIOLOGICAL: Td5ap|BIOLOGICAL: Td1aP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gastrectomy + Cytoreductive Surgery + HIPEC for Gastric Cancer With Peritoneal Dissemination.
Status: RECRUITING
Conditions: Stomach Neoplasm|Peritoneal Carcinomatosis
Interventions: PROCEDURE: Cytoreductive surgery + Gastrecomy|DRUG: Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Contrast Nephropathy During Diagnostic Coronary Angiogram or PCI With Hydratation Based on LEVDP
Status: UNKNOWN
Conditions: Radiographic Contrast Agent Nephropathy|Renal Failure|Coronary Heart Disease
Interventions: OTHER: Hydratation according LVEDP + NaHCO3|OTHER: normal saline|OTHER: Sodium bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who Are HLA-DP0401 Positive
Status: COMPLETED
Conditions: Cervical Cancer|Renal Cancer|Urothelial Cancer|Melanoma|Breast Cancer
Interventions: BIOLOGICAL: Anti-MAGE-A3-DP4 T Cell Receptor (TCR) Peripheral Blood Lymphocytes (PBL)|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Pulmonary Hypertension in High-risk Cardiac Surgery Patients Using Inhalational and Intravenous Agents
Status: RECRUITING
Conditions: Hypertension, Pulmonary|Cardiac Failure|Pulmonary Vascular Resistance Abnormality
Interventions: DRUG: levosimendan at a dose of 6 mcg/kg|DRUG: milrinone at a dose of 50 mcg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: AlloGeneic Human Mesenchymal Stem Cells (hMSC) in PAtients With FistuLizing Crohn's Disease Via PErifistula iNjEctions (GALENE)
Status: WITHDRAWN
Conditions: Crohn's Disease|Fistulizing Crohn's Disease|Stem Cells
Interventions: DRUG: Allogeneic Bone Marrow derived Human Mesenchymal Stem Cells (hMSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SentoClone® Compared to Reference Treatment in Advanced Malignant Melanoma
Status: UNKNOWN
Conditions: Malignant Melanoma
Interventions: BIOLOGICAL: SentoClone®|DRUG: Temodal® or Dacarbazine Medac®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation on the Human Airway: Mucus Secretion, Inflammatory and Proteomic Profile in Nose and miRNAs in Blood
Status: UNKNOWN
Conditions: Smoking|Smoking Cessation
Interventions: BEHAVIORAL: Smoking cessation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Efficacy and Safety Study of Guanxin Shutong Capsule to Treat Chronic Stable Angina
Status: UNKNOWN
Conditions: Angina, Stable
Interventions: DRUG: Guanxin Shutong Capsule|DRUG: Placebo Capsule|DRUG: nitroglycerine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of BO-112 With Radiotherapy and Nivolumab for Metastatic Refractory NSCLC
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer Metastatic
Interventions: DRUG: BO-112 in combination with ablative radiotherapy (SABR) and nivolumab|PROCEDURE: Tissue Biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of IFX and TNF Concentrations in Serum, Stool, and Colonic Mucosa in Acute Severe Ulcerative Colitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Infliximab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the BASKA Airway, a Novel Supraglottic Device, to the LMA Airway in Low Risk Female Patients
Status: COMPLETED
Conditions: Performance and Safety of an Airway Management Device
Interventions: DEVICE: supraglottic airway placement and use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Evaluate a Temporary Skin Substitute (Spincare® Matrix) for Wound Healing in RDEB Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Recessive Dystrophic Epidermolysis Bullosa
Interventions: DEVICE: Spincare matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Bactericidal Activity of TBA-7371 in Pulmonary Tuberculosis
Status: COMPLETED
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: TBA-7371|DRUG: TBA-7371|DRUG: TBA-7371|DRUG: TBA-7371|DRUG: TBA-7371|DRUG: HRZE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of BL-M07D1 in Patients With HER2-expressing Recurrent or Metastatic Gynecologic Malignancies
Status: RECRUITING
Conditions: Gynecological Malignancies
Interventions: DRUG: BL-M07D1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human-Machine System for the H2 Lower Limb Exoskeleton
Status: UNKNOWN
Conditions: Stroke|Hemiparesis
Interventions: BEHAVIORAL: Robot-assisted training with the H2 lower limb powered exoskeleton|BEHAVIORAL: Supervised motor practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of Substitution of Focused Cliches and Ultrasound for Tomosynthesis
Status: COMPLETED
Conditions: Breast Cancer|2D Mammography|3D Mammography
Interventions: DEVICE: tomosynthesis|DEVICE: 2D mammography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effect of Electroacupuncture on Benign Prostatic Hyperplasia
Status: RECRUITING
Conditions: Benign Prostatic Hyperplasia
Interventions: DEVICE: Electroacupuncture|DEVICE: Sham electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telephone Acceptance and Commitment Therapy Intervention for Caregivers of Adults With Dementia
Status: COMPLETED
Conditions: Anxiety|Anxiety Generalized|Anxiety Disorders and Symptoms|Caregiver Burnout
Interventions: BEHAVIORAL: Telephone Acceptance and Commitment Therapy Intervention for Caregivers|BEHAVIORAL: minimally-Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembro With Radiation With or Without Olaparib
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Olaparib|DRUG: Androgen Deprivation Therapy|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Switching From an SSRI to Tiagabine(GABITRIL) in Order to Alleviate SSRI Induced Sexual Dysfunction
Status: COMPLETED
Conditions: Anxiety|Sexual Dysfunction
Interventions: DRUG: Gaitril
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sublingual Versus Endovenous Fentanyl for the Prehospital Analgesia in Patients With Limb Trauma on the Slope
Status: COMPLETED
Conditions: Acute Pain Due to Trauma
Interventions: DRUG: Fentanyl sublingual|DRUG: Fentanyl ev|DRUG: Placebo sublingual|DRUG: Placebo ev
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Rinsulin® NPH, Suspension for Subcutaneous Administration, 100 IU/ml (GEROPHARM LLC, Russia) and Humulin® NPH, Suspension for Subcutaneous Administration, 100 IU/ml (Lilly France, France) Using the Euglycemic Hyperinsulinemic Clamp Method
Status: COMPLETED
Conditions: Pharmacokinetics|Bioequivalence
Interventions: DRUG: Rinsulin NPH|DRUG: Humulin NPH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Oral AT2101 (Afegostat Tartrate) in Treatment-naive Patients With Gaucher Disease
Status: COMPLETED
Conditions: Gaucher Disease|Type 1 Gaucher Disease|Gaucher Disease, Type 1
Interventions: DRUG: afegostat tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Urban Cervical Cancer Disparities
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer|Papilloma Viral Infection
Interventions: BEHAVIORAL: Stage 1 SOC|BEHAVIORAL: Stage 1 HERS|BEHAVIORAL: Stage 2 HERS|BEHAVIORAL: Stage 2 HERS+HC|BEHAVIORAL: Stage 3 SOC|BEHAVIORAL: Stage 3 HERS|BEHAVIORAL: Stage 3 HERS+HC|BEHAVIORAL: Stage 4 HERS|BEHAVIORAL: Stage 4 HERS+HC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Therapeutic Use of Angiopoietin-Primed Autologous Peripheral Blood Stem Cell in Myocardial Infarction
Status: NOT_YET_RECRUITING
Conditions: Acute Myocardial Infarction
Interventions: BIOLOGICAL: Autologous Peripheral Blood Stem Cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Folic Acid in Preventing Colorectal Polyps in Patients With Previous Colorectal Polyps
Status: COMPLETED
Conditions: Adenoma of Large Intestine
Interventions: DIETARY_SUPPLEMENT: Folic acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Status: RECRUITING
Conditions: Advanced Solid Tumor|Advanced Malignant Neoplasm|Metastatic Cancer|Metastatic Solid Tumor|Lung Cancer|Ovarian Cancer|Endometrial Cancer|Prostate Cancer|Colorectal Cancer|Breast Cancer|Other Cancer|Locally Advanced|Head and Neck Cancer
Interventions: DRUG: PC14586|DRUG: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Indobufen and Aspirin in Patients With Coronary Atherosclerosis
Status: UNKNOWN
Conditions: Coronary Atherosclerosis
Interventions: DRUG: aspirin 100 mg/d|DRUG: indobufen 200 mg bid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of VBP-245 in Pediatric Patients With Molluscum Contagiosum
Status: COMPLETED
Conditions: Molluscum Contagiosum
Interventions: DRUG: VBP-245 Topical Gel|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Patient Expectations With Lateral Epicondylalgia in Applying Mobilization With Movement
Status: COMPLETED
Conditions: Tennis Elbow
Interventions: BEHAVIORAL: Positive Expectations|PROCEDURE: Mobilization with movement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of ALLO-605 an Anti-BCMA Allogeneic CAR T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: GENETIC: ALLO-605|BIOLOGICAL: ALLO-647|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation and Management of Parturients' Pain Intensity
Status: WITHDRAWN
Conditions: Labor Pain
Interventions: BEHAVIORAL: ABM affective pain stimuli|BEHAVIORAL: ABM sensory pain stimuli|BEHAVIORAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Treating Primary Progressive Aphasia and Apraxia of Speech Using Non-invasive Brain Stimulation
Status: ENROLLING_BY_INVITATION
Conditions: Primary Progressive Aphasia|Apraxia of Speech
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Aldara as an Adjunct to Laser Treatment
Status: TERMINATED
Conditions: Port Wine Stains
Interventions: DRUG: Imiquimod|DRUG: non-medicated petroleum cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Statins in Reducing Events in the Elderly Mind (STAREE-Mind) Imaging Substudy
Status: ACTIVE_NOT_RECRUITING
Conditions: Dementia, Mixed|Dementia, Vascular|Dementia of Alzheimer Type|Cognitive Decline|White Matter Hyperintensity|Aging|Neuro-Degenerative Disease
Interventions: DRUG: Atorvastatin 40 Mg Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Strategies to Reduce Injuries and Develop Confidence in Elders
Status: COMPLETED
Conditions: Accidental Falls|Wounds and Injuries
Interventions: OTHER: Evidence-based tailored fall prevention|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Development of Variable Volume Automated Mandatory Boluses for Patient-controlled Epidural Analgesia During Labour
Status: RECRUITING
Conditions: Labor Pain|Breakthrough Pain
Interventions: DEVICE: Epidural infusion pump|DRUG: Ropivacaine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study for Women With Platinum Resistant Ovarian Cancer Evaluating EC145 in Combination With Doxil® (PROCEED)
Status: TERMINATED
Conditions: Ovarian Cancer
Interventions: DRUG: EC145|DRUG: Pegylated Liposomal Doxorubicin (PLD/Doxil®/Caelyx®)|DRUG: placebo|DRUG: EC20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Neoadjuvant E7 TCR T Cell Immunotherapy for Borderline Resectable and Unresectable Stage I HPV-Associated Oropharyngeal Cancer
Status: WITHDRAWN
Conditions: Papillomavirus Infections|Oropharyngeal Neoplasms
Interventions: BIOLOGICAL: E7 TCR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PI3K Inhibitors for the Treatment of Relapsed/Refractory Indolent T/NK-cell Lymphomas
Status: RECRUITING
Conditions: Lymphoma, T-Cell|NK-LGL Leukemia|T-LGL Leukemia
Interventions: DRUG: PI3K inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of Human Cord Blood Derived, Culture-expanded, Natural Killer Cell (PNK-007) Infusion With or Without Subcutaneous Recombinant Human Interleukin-2 (rhIL-2) Following Autologous Stem Cell Transplant for Multiple Myeloma (MM)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: rhIL-2|BIOLOGICAL: PNK-007
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SSIPP vs. PST vs. WLC
Status: WITHDRAWN
Conditions: Major Depressive Disorder|Late Life Depression
Interventions: BEHAVIORAL: Student-Senior Isolation Prevention Partnership (SSIPP)|BEHAVIORAL: Problem Solving Therapy (PST).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Oral Ketamine Versus Placebo for the Treatment of Anxiety in Patients With Pancreatic Cancer
Status: RECRUITING
Conditions: Anxiety|Pancreatic Cancer
Interventions: DRUG: Ketamine|DRUG: Placebo|DRUG: Placebo|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE