pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Novel Treatment to Boost Quit Attempts and Cessation Among Unmotivated Smokers
Status: COMPLETED
Conditions: Smoking|Smoking Cessation
Interventions: OTHER: Practice Quit Attempt plus nicotine lozenge|BEHAVIORAL: Practice Quit Attempt only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Flavonoids on Gut Permeability in Cyclists
Status: COMPLETED
Conditions: Gut Permeability, Gut Inflammation
Interventions: DRUG: Low flavonoid beverage|DRUG: High flavonoid beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Fosaprepitant for the Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV) in Children (MK-0517-029)
Status: COMPLETED
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Fosaprepitant|DRUG: Fosaprepitant Placebo|DRUG: Ondansetron|DRUG: 5-hydroxytryptamine 3 antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment for Calcium Phosphate Kidney Stone Disease
Status: COMPLETED
Conditions: Calcium Phosphate Kidney Stones
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Citric Acid|DIETARY_SUPPLEMENT: Potassium Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Auditory Nerve Test System During Vestibular Schwannoma Resection
Status: COMPLETED
Conditions: Vestibular Schwannoma|Acoustic Neuroma|Sensorineural Hearing Loss|Asymmetric Sensorineural Hearing Loss|Cochlear Nerve Damage|Cochlear Nerve Deafness|Skull Base Neoplasms|Auditory; Nerve
Interventions: DEVICE: Auditory Nerve Test System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Efficacy of Dapagliflozin on Recurrence After Catheter Ablation for Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: Dapagliflozin 10 mg per day for 3 months after initial catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gut Microbiome Modulation to Enable Efficacy of Checkpoint-based Immunotherapy in Pancreatic Adenocarcinoma
Status: WITHDRAWN
Conditions: Pancreatic Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Ciprofloxacin 500mg PO BID days 1-29|DRUG: Metronidazole 500mg PO TID days 1-29
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of False Positives From First-trimester Preeclampsia Screening (StopPRE) at the Second-trimester of Pregnancy
Status: COMPLETED
Conditions: Pre-Eclampsia
Interventions: DRUG: ASA-withdrawn group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Hypertension Secondary to Idiopathic Pulmonary Fibrosis And Treatment With Sildenafil
Status: WITHDRAWN
Conditions: Pulmonary Arterial Hypertension|Idiopathic Pulmonary Fibrosis|Interstitial Lung Disease|Pulmonary Hypertension
Interventions: DRUG: sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telerehabilitation-based Yoga and Mindfulness Home Program in Postmenopausal Women Having Social Isolation
Status: COMPLETED
Conditions: Telerehabilitation
Interventions: OTHER: Telerehabilitation-Based|OTHER: Video-Based
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Define the ECG Effects of Tizanidine Compared to Placebo and the Positive Control, Moxifloxacin, in Healthy Men and Women Using a Blinded ECG Evaluator: A Thorough ECG Trial
Status: COMPLETED
Conditions: Spasticity
Interventions: DRUG: Tizanidine|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SHR-A1811 Combined With Bevacizumab in HER2-positive Breast Cancer With Brain Metastases
Status: NOT_YET_RECRUITING
Conditions: Breasr Cancer
Interventions: DRUG: SHR-A1811|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Efficacy of the Association Nimotuzumab(HR3) /Cisplatin-Vinorelbine on Patients With Cervical Carcinom
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: BIOLOGICAL: Nimotuzumab ( h-R3)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimize First-line Treatment for AL Amyloidosis With t (11; 14)
Status: RECRUITING
Conditions: Amyloidosis; Systemic|AL Amyloidosis
Interventions: DRUG: Daratumumab|DRUG: Bortezomib|DRUG: Dexamethasone|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy,Tolerability,Safety of Temsirolimus in Women With Platinum-refractory Ovarian Carcinoma or Advanced Endometrial Carcinoma
Status: COMPLETED
Conditions: Genital Diseases, Female|Ovarian Diseases|Ovarian Neoplasms|Endometrial Neoplasms
Interventions: DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rucaparib vs Placebo Maintenance Therapy in Metastatic and Recurrent Endometrial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Endometrial Cancer
Interventions: DRUG: Rucaparib|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact on Muscle Strength, Quality of Life and Functionality in Individuals Submitted to Hip Arthroplasty: a Prospective Study.
Status: COMPLETED
Conditions: Arthroplasty Complications|Arthropathy of Hip
Interventions: DIAGNOSTIC_TEST: Muscle Strenght assesment|DIAGNOSTIC_TEST: 2D Kinematics Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treating Diabetic Foot Ulcers, Comparing Two Topical Antimicrobial Agents, Dakin´s and Prontosan
Status: RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: Dakins Full Strength Solution, 0.5% Topical Solution, HOCl solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Enteral Nutrition for Dose Reduction of Low Dose PEG
Status: UNKNOWN
Conditions: Bowel Preparation
Interventions: DIETARY_SUPPLEMENT: Enteral Nutrition Powder Ensure|DRUG: 1.5L PEG|OTHER: Self-controlled diet|DRUG: 2L PEG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Correlation Between Microbial Infection and Lumbar Degenerative Disease Based on High-throughput Gene Sequencing
Status: RECRUITING
Conditions: Lumbar Degenerative Diseases|Gene Product Sequence Variation
Interventions: OTHER: Lumbar disc herniation|OTHER: Lumbar spinal stenosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Momordica Charantia Administration on Anthropometric Indicators in Patients With Obesity
Status: UNKNOWN
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Momordica charantia|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Combined Modality Treatment in Primary Testicular Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma, B Cell
Interventions: DRUG: rituximab|DRUG: CHOP|DRUG: intrathecal methotrexate|PROCEDURE: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prognostic Accuracy of qSOFA, SIRS, and EWSs for In-hospital Mortality in Emergency Department
Status: COMPLETED
Conditions: Sepsis|Septic Shock
Interventions: DIAGNOSTIC_TEST: Measurement of qSOFA score|DIAGNOSTIC_TEST: Measurement of SIRS criteria|DIAGNOSTIC_TEST: Measurement of NEWS|DIAGNOSTIC_TEST: Measurement of NEWS2|DIAGNOSTIC_TEST: Measurement of MEWS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Morbimortality of Covid-19 in Patients With Chronic Inflammatory Rheumatism Treated With Immunosuppressants
Status: TERMINATED
Conditions: Sars-CoV2|Rheumatoid Arthritis|Rheumatic Diseases
Interventions: OTHER: questionnaire assesment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Oral Alitretinoin (Toctino®) in the Treatment of Patients With Cutaneous Lupus Erythematosus
Status: TERMINATED
Conditions: Lupus Erythematosus, Cutaneous
Interventions: DRUG: Alitretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Children's Cognitive Function and Achievement Through Carotenoid Consumption
Status: RECRUITING
Conditions: Cognitive Change|Achievement|Macular Pigmentation
Interventions: DIETARY_SUPPLEMENT: Active supplement|DIETARY_SUPPLEMENT: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acute Sore Throat Pain Study
Status: COMPLETED
Conditions: Acute Sore Throat Pain
Interventions: DRUG: Placebo|DRUG: Ibuprofen 35 mg|DRUG: Ibuprofen 25 mg|DRUG: Ibuprofen 15 mg|DRUG: Strefen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a New System for Heart Rate and SpO2 Measurement.
Status: UNKNOWN
Conditions: Telemedicine
Interventions: DEVICE: Heart rate measurement with Caducy system (twice). SpO2 measurement with Caducy system (Twice).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Telbivudine Renoprotective Effect in Patients With HBV-related Liver Cirrhosis
Status: UNKNOWN
Conditions: HBV-related Liver Cirrhosis
Interventions: DRUG: Telbivudine, Lamivudine, Adefovir ,Enecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1- Mediated Proteinuric Kidney Disease
Status: RECRUITING
Conditions: Proteinuric Kidney Disease
Interventions: DRUG: VX-147|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Rollover Trial for Patients Randomized to the Control Group of Study LSH-10-001
Status: UNKNOWN
Conditions: Heart Failure|Cardiomyopathy|Dilated Cardiomyopathy
Interventions: DEVICE: Algisyl-LVR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Depot Formulation of Sunitinib Malate (GB-102) Compared to Aflibercept in Subjects With Wet AMD
Status: COMPLETED
Conditions: Neovascular Age-Related Macular Degeneration
Interventions: DRUG: Drug: GB-102|DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MK0217A and Dietary Supplement in Men and Postmenopausal Women With Osteoporosis (0217A-227)
Status: COMPLETED
Conditions: Osteoporosis|Vitamin D Deficiency
Interventions: DRUG: MK0217A, alendronate sodium (+) cholecalciferol / Duration of Treatment: 24 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early or Delayed Revascularization for Intermediate and High-risk Non ST-elevation Acute Coronary Syndromes?
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: PROCEDURE: Percutaneous coronary intervention for revascularization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Switch Maintenance in Pancreatic
Status: RECRUITING
Conditions: Pancreatic Cancer|Adenocarcinoma of the Pancreas|Squamous Cell Carcinoma of Pancreas|Adenosquamous Carcinoma of the Pancreas
Interventions: DRUG: ZIMBERELIMAB|DRUG: DOMVANALIMAB|DRUG: APX005M|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-operative Preparation Using 2% Chlorhexidine Cloth For Shoulder Surgery
Status: COMPLETED
Conditions: Post-operative Surgical Site Infections
Interventions: DRUG: 2% Chlorhexidine cloth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ideas Moving Parents and Adolescents to Change Together (IMPACT)
Status: COMPLETED
Conditions: Overweight|Obese
Interventions: BEHAVIORAL: HealthyCHANGE|BEHAVIORAL: SystemCHANGE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-thrombotic Syndrome & Predictors of Recurrence in Catheter-related Thrombosis
Status: COMPLETED
Conditions: Venous Thrombosis|Neoplasms
Interventions: DRUG: Heparin, Low-Molecular-Weight, or direct oral anticoagulants
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Open Label Evaluation of the Pharmacokinetics and Safety of Single Dose Intravenous Azithromycin in Preterm Neonates
Status: COMPLETED
Conditions: Ureaplasma|Bacterial Infection
Interventions: DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lactobacillus Rhamnosus GG and Bifidobacterium Longum in Children Aged 3 to 5 Years of Villavicencio and Pasto
Status: COMPLETED
Conditions: Caries, Dental
Interventions: DIETARY_SUPPLEMENT: Commercial Dairy Cow Milk|DIETARY_SUPPLEMENT: Commercial Cow Milk with Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Identification of a Predictive Metabolic Signature of Response to Immune Checkpoint Inhibitors in Non-Small Cell Lung Carcinoma
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: OTHER: Immune signature in serum associated to the metabolic signature|GENETIC: Meta-genomic signature of intestinal flora
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acute Intermittent Hypoxia and Body Weight Supported Treadmill Training for Incomplete Spinal Cord Injury Patients
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: OTHER: Acute Intermittent Hypoxia|OTHER: Body weight-assisted treadmill training|OTHER: Sham Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Structural and Functional Brain Reorganization in Neuropathic Pain. Influences of the Loss of Sensitivity and the Atrophy Cortical on Activations Due to Stimulation Allodynic
Status: TERMINATED
Conditions: Neuropathic Pain
Interventions: OTHER: stimulation on painful area (area allodynic)|OTHER: same stimulation on non-painful area|RADIATION: MRI scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Endoscopic Assessment and Prediction of Microbiome-modifying Interventions
Status: UNKNOWN
Conditions: Gut Microbiome|Antibiotic Side Effect
Interventions: DIETARY_SUPPLEMENT: Probiotic treatment|BIOLOGICAL: Bacteriotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-bypass Prophylactic IVIG in Infants and Neonates
Status: COMPLETED
Conditions: Hypogammaglobulinemia|Congenital Heart Disease
Interventions: DRUG: IVIG|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of IBI311 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: placebo|BIOLOGICAL: IBI311|BIOLOGICAL: IBI311|BIOLOGICAL: placebo|BIOLOGICAL: placebo|BIOLOGICAL: IBI311|BIOLOGICAL: IBI311|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Pharmacokinetic Interaction Between Rosuvastatin and Olmesartan in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rosuvastatin|DRUG: Olmesartan|DRUG: Rosuvastatin and olmesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Satralizumab (SA237) as Monotherapy to Treat Participants With Neuromyelitis Optica (NMO) and Neuromyelitis Optica Spectrum Disorder (NMOSD)
Status: COMPLETED
Conditions: Neuromyelitis Optica (NMO)|NMO Spectrum Disorder (NMOSD)
Interventions: DRUG: Satralizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Trial to Estimate Proportion of Patients With Tumor Cell Contaminated Leukapheresis Products With and Without Bortezomib With In-vivo Purging - Multiple Myeloma (MM)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib|DRUG: Granulocyte colony-stimulating factor (G-CSF)|DRUG: Mozobil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Effectiveness for Connected Network for EMS Comprehensive Technical-support Using Artificial Intelligence (CONNECT-AI) System by Community Intervention
Status: COMPLETED
Conditions: Emergency Patient Transported by Ambulance
Interventions: OTHER: CONNECT AI system group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Danish Familial Hypercholesterolemia Organized Coronary Screening Trial
Status: RECRUITING
Conditions: Familial Hypercholesterolemia|Atherosclerosis
Interventions: BEHAVIORAL: Visualization of coronary Imaging and oral description
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: LA Moms and Babies Study (LAMBS) for Nutrition and Growth
Status: WITHDRAWN
Conditions: Pregnancy|Inflammation
Interventions: DIETARY_SUPPLEMENT: Capsule 1 or Capsule 2|DIETARY_SUPPLEMENT: Capsule 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: First-in-human Experience Using Novel Ultraflexible Low-impedance Electrode Arrays: an IDEAL Stage 1 Study
Status: NOT_YET_RECRUITING
Conditions: Epilepsy|Focal Cortical Dysplasia
Interventions: DEVICE: Insertion of electrode during planned neurosurgery for epilepsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Study of an Insulin Management System in Participants With Type 1 or Type 2 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes|Type 2 Diabetes
Interventions: DEVICE: IIM System|DRUG: Insulin Lispro and/or Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Long-term Effects of Imiquimod and Diclofenac in Actinic Keratoses (LEIDA 2)
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Imiquimod|DRUG: Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin in Preventing Androgen Deprivation Therapy Induced Insulin Resistance and Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome|Hypercholesterolemia
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Tolerability and Safety of Converting Stable Renal Transplant Recipients Who Receive Tacrolimus With or Without Corticosteroids From Mycophenolate Mofetil (MMF) to Enteric-coated Mycophenolate Sodium (EC-MPS)
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: DRUG: Enteric-Coated Mycophenolate Sodium (EC-MPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Psychological Resilience and Psychological Well-being of Intensive Care Nurses
Status: UNKNOWN
Conditions: Psychological Resilience|Well-being
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction Intervention|OTHER: no intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety and Tolerability of Tecarfarin in Healthy Chinese Volunteers
Status: COMPLETED
Conditions: Pharmacokinetic and Pharmacodynamic Profile of Tecarfarin
Interventions: DRUG: Tecarfarin 10mg|DRUG: Tecarfarin 20mg|DRUG: Tecarfarin 30mg|DRUG: Tecarfarin 40mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mobilization With Movement for Shoulder Impingement
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome
Interventions: OTHER: Real mobilization-with-movement (MWM)|OTHER: Sham mobilization-with-movement (MWM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AVAD: Asthma With Small Airways Dysfunction
Status: TERMINATED
Conditions: ASTHMA
Interventions: GENETIC: asthma with proximal airways obstruction phenotype profile description with clinical, biological, morphologic and genetic elements.|GENETIC: asthma with small airways dysfunction phenotype profile description with clinical, biological, morphologic and genetic elements.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioavailability of Iodine for Natural Kelp and Iodized Salt in Young Adults
Status: UNKNOWN
Conditions: Iodine Bioavailability
Interventions: DIETARY_SUPPLEMENT: iodine-containg spareribs soup|DIETARY_SUPPLEMENT: intrinsic iodine in natural kelp
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Drug-Drug Interaction Study With Rifampin
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: BMS-708163|DRUG: Rifampin|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma|Small Cell Glioblastoma|Giant Cell Glioblastoma|Gliosarcoma|Glioblastoma With Oligodendroglial Component
Interventions: DRUG: Rindopepimut (CDX-110) with GM-CSF|DRUG: Temozolomide|DRUG: KLH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immune Globulin Intravenous (IGIV) To Treat Relapsing, Remitting Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Immune Globulin IV [Human], 10% Caprylate/Chromatography Purified|DRUG: Albumin (Human) 25%, United States Pharmacopeia (USP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bolus Versus Continuous Enteral Tube Feeding
Status: COMPLETED
Conditions: Trauma Injury|Major Abdominal Surgery|Sepsis
Interventions: DIAGNOSTIC_TEST: Quadriceps Muscle Layer Fitness|DIAGNOSTIC_TEST: Muscle Strength|DIAGNOSTIC_TEST: Acute Physiology and Chronic Health Evaluation|DIAGNOSTIC_TEST: Sequential Organ Failure Assessment|DIAGNOSTIC_TEST: Nutritional Risk Screening|DIAGNOSTIC_TEST: Energy and Protein Intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Paclitaxel and Carboplatin With or Without Celecoxib Before Surgery in Treating Patients With Stage IIIA Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: celecoxib|DRUG: paclitaxel|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Individualized Precise Radiotherapy With the Guidance of Radiosensitivity of Locally Advanced Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: BIOLOGICAL: 18F-FDG PET/CT and Comet assay guide RapidArc|BIOLOGICAL: 18F-FDG PET/CT and Comet assay guide IMRT|BIOLOGICAL: RapidArc|BIOLOGICAL: 7f-IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lacidofil® STRONG as an Adjuvant for Helicobacter Pylori Treatment in Non-ulcer Dyspepsia
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DIETARY_SUPPLEMENT: Lacidofil|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Effect on the Glucose Infusion Rates Between Inhaled Technosphere Insulin and a Subcutaneous Injection of Regular Human Insulin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Technosphere Insulin|DRUG: Technosphere insulin|DRUG: Technosphere insulin|DRUG: Regular human insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sacituzumab Govitecan Combined With Head Radiotherapy for Her2-negative Breast Cancer Brain Metastases
Status: NOT_YET_RECRUITING
Conditions: Brain Metastasis
Interventions: DRUG: Sacituzumab Govitecan|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Bevacizumab vs Laser vs Combination of Bevacizumab and Modified Laser in PDR
Status: UNKNOWN
Conditions: Proliferative Diabetic Retinopathy
Interventions: DRUG: receive 4 monthly IVB injections and then rescue IVB|DRUG: PRP group|DRUG: IVB injections and a modified laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Dato-DXd|DRUG: Durvalumab|DRUG: Pembrolizumab|DRUG: Doxorubicin|DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Capecitabine|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dry Needling Using Spinal and Peripheral Sites Versus Peripheral Sites Only
Status: COMPLETED
Conditions: Plantar Fasciitis|Achilles Tendinitis|Patellofemoral Pain Syndrome
Interventions: PROCEDURE: Spinal and Peripheral Dry Needling|PROCEDURE: Peripheral Dry Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Immunogenicity of 1 Booster Dose of 1790GAHB Vaccine in Healthy Adults Primed With 3 Doses of 1790GAHB Vaccine in Study H03_01TP Compared to 1 Vaccination of 1790GAHB in Either Subjects Who Received Placebo in the Same Study or naïve Subjects Not Part of H03_01TP Study
Status: COMPLETED
Conditions: Dysentery, Bacillary
Interventions: BIOLOGICAL: GVGH Shigella sonnei 1790GAHB vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Aspirin in the Prevention of Cardiovascular Events in Hemodialysis Patients
Status: WITHDRAWN
Conditions: End-Stage Renal Disease
Interventions: DRUG: aspirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of FMT in Patients With CID
Status: ACTIVE_NOT_RECRUITING
Conditions: Insomnia Chronic|Fecal Microbiota Transplantation|Sleep Disorder|Depression|Anxiety|Cognitive Impairment
Interventions: BIOLOGICAL: fecal microbiota
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of TAR-302-5018 in Subjects With Idiopathic Overactive Bladder
Status: COMPLETED
Conditions: Idiopathic Overactive Bladder With Urinary Incontinence
Interventions: DRUG: Trospium-Releasing Intravesical System (TAR-302-5018)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Testofen on Erectile Function in an Adult Male Population
Status: RECRUITING
Conditions: Erectile Dysfunction
Interventions: DRUG: Testofen 300mg|DRUG: Testofen 600mg|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Arformoterol Tartrate Inhalation Solution in Chronic Obstructive Pulmonary Disease (COPD) Subjects
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Arformoterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myocardial Regeneration and Angiogenesis in Myocardial Infarction With G-CSF and Intra-Coronary Stem Cell Infusion
Status: TERMINATED
Conditions: Myocardial Infarction
Interventions: DRUG: Drug: G-CSF (Dong-A pharmaceutical, Seoul, Korea)|PROCEDURE: collection of mobilized peripheral blood stem cells|PROCEDURE: Intracoronary infusion of mobilized cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Intensity Training in de Novo Heart Transplant Recipients in Scandinavia
Status: COMPLETED
Conditions: Heart Transplant Recipients|Physical Fitness
Interventions: BEHAVIORAL: High Intensity Interval Training|BEHAVIORAL: Moderate Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Procalcitonin to Guide Obtaining Bloodcultures in the ICU Intensive Care Infection Score
Status: COMPLETED
Conditions: Infection
Interventions: OTHER: Procalcitonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: PROTEUS: Evaluating the Use of Artificial Intelligence to Support Stress Echocardiography Testing for Heart Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Heart Disease
Interventions: DIAGNOSTIC_TEST: EchoGo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Four-Week Multicenter Study Evaluating the Safety and Efficacy of Gefapixant (AF-219/MK-7264) in Subjects With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Gefapixant|DRUG: Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Simvastatin for at Least 4 Weeks.
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: colesevelam HCl tablets, and simvastatin tablets|DRUG: simvastatin tablets and colesevelam HCl placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Epidural Analgesia and Local Infiltrative Analgesia Methods on Pain Control
Status: COMPLETED
Conditions: Epidural Anesthesia
Interventions: DEVICE: 18-Gauge Touhy (Egemen®, Combifix Standard Spinal Epidural Combined Set, İzmir, Turkey)|DEVICE: 20-gauge infiltrative analgesia catheter connected to an ON-Q elastomeric pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Acute Impact of Sit-stand Desks on Post-meal Blood Sugar Levels
Status: COMPLETED
Conditions: Insulin Sensitivity|Glucose Tolerance|Sedentary Behaviour|Physical Activity
Interventions: BEHAVIORAL: Sit-stand desk|BEHAVIORAL: Sitting desk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Hybrid Telerehabilitation-Based Structured Exercise Programs in Patients With Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine, Bevacizumab, and Radiation Therapy Followed By Gemcitabine and Bevacizumab in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Adenocarcinoma of the Pancreas|Stage II Pancreatic Cancer|Stage III Pancreatic Cancer
Interventions: DRUG: capecitabine|RADIATION: radiation therapy|BIOLOGICAL: bevacizumab|PROCEDURE: therapeutic conventional surgery|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EffectS of prEferred Music on Laparoscopic performancE
Status: COMPLETED
Conditions: Laparoscopic Surgery|Music|Surgical Education
Interventions: OTHER: Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Conscious Sedation for Outpatient Colonoscopy
Status: COMPLETED
Conditions: Conscious Sedation
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A 12 Week Study in Patients With Type 2 Diabetes Mellitus (T2DM)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: LCQ908A|DRUG: LCQ908A|DRUG: LCQ908A|DRUG: LCQ908A|DRUG: LCQ908A|DRUG: Placebo|DRUG: Sitagliptin|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of NNZ-2566 in Healthy Female Subjects
Status: COMPLETED
Conditions: Brain Injuries, Traumatic
Interventions: DRUG: NNZ-2566|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health Effects of Grain Foods in Adults
Status: RECRUITING
Conditions: High Whole Grain and Low Sugar|Medium Whole Grain and Low Sugar|Low Whole Grain and Low Sugar|Low Whole Grain and High Sugar
Interventions: OTHER: High Whole Grain, Low Sugar|OTHER: Low Whole Grain, Low Sugar|OTHER: High Whole Grain, High Sugar|OTHER: Low Whole Grain, High Sugar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Cold Gel Pack Application on Itching in Burn Patients in the Maturation Stage
Status: RECRUITING
Conditions: Burns|Pruritus
Interventions: OTHER: Cold Gel Packet Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sitagliptin Metformin/PPARg Agonist Combination Therapy Add-on (0431-052)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: sitagliptin|DRUG: Comparator: Placebo|DRUG: rosiglitazone|DRUG: metformin|DRUG: glipizide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Management of Pseudophakic and Aphakic Retinal Detachment; a Randomized Clinical Trial
Status: UNKNOWN
Conditions: Pseudophakic Retinal Detachment|Aphakic Retinal Detachment
Interventions: PROCEDURE: scleral buckling, primary vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects (Long Term Analysis) of an Hyperproteinic Nutrition on Neonates With Intra-uterine Growth Delay : a Prospective, Multicentric , Randomized, Double Blind Study ("Proneonat")
Status: TERMINATED
Conditions: Intra-uterine Growth Delay
Interventions: OTHER: milk enriched in proteins (2.15 g/100ml)|OTHER: milk with normal protein concentration (1.45g/100ml)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Rectal Suppository Acetaminophen and Diclofenac Sodium as Analgesia for Postpartum Perineal Tear
Status: COMPLETED
Conditions: Perineal Tear|Perineal Laceration (Obstetric)
Interventions: DRUG: Diclofenac Sodium 50Mg Suppository|DRUG: Paracetamol 500Mg Suppository
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Arginin and Potassium Nitrate Dentifrices in Dentin Hypersensitivity Therapy
Status: UNKNOWN
Conditions: Dentin Sensitivity
Interventions: DRUG: 8% arginine/1450ppm sodium monofluorophosphate dentifrice|DRUG: 5% potassium nitrate/2500ppm sodium fluoride dentifrice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Participation in Universal School Meals (USM)
Status: NOT_YET_RECRUITING
Conditions: Food Deprivation|Obesity, Childhood
Interventions: OTHER: Implementation Mapping|OTHER: Waitlist Control - Implementation Mapping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The PAH Platform for Deep Phenotyping in Korean Subjects
Status: UNKNOWN
Conditions: Pulmonary Arterial Hypertension|Deep Phenotyping|Idiopathic Pulmonary Arterial Hypertension|Heritable Pulmonary Arterial Hypertension
Interventions: DIAGNOSTIC_TEST: Deep phenotyping
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Rabeprazole and Esomperazole for the Eradication of H. Pylori
Status: COMPLETED
Conditions: H. Pylori Infection
Interventions: DRUG: rabeprazole-based regimen|DRUG: esomeprazole^based regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of SNX281 in Subjects With Advanced Solid Tumors and Lymphoma
Status: TERMINATED
Conditions: Advanced Solid Tumor|Advanced Lymphoma
Interventions: DRUG: SNX281|DRUG: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining Lateralized Aspects of Motor Control Using Non-invasive Neural Stimulation
Status: RECRUITING
Conditions: Motor Adaptation and Generalization|Posterior Parietal Cortex|Cerebellum
Interventions: BEHAVIORAL: Comparing motor adaptation reaching performance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Competitive Revision for CLARO: Collaboration Leading to Addiction Treatment and Recovery From Other Stresses
Status: COMPLETED
Conditions: Opioid-use Disorder|Addiction|Depression|Post Traumatic Stress Disorder|Suicidal Ideation
Interventions: BEHAVIORAL: Collaborative care Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of GlaxoSmithKline Biologicals' Huma Papillomavirus (HPV) Vaccine 580299 in Healthy Females 15 - 25 Years of Age
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: Cervarix TM|BIOLOGICAL: Cervarix TM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Influence of Early Coronal Flaring Upon Postoperative Pain After Root Canal Treatment
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: PROCEDURE: coronal flaring|PROCEDURE: Non coronal flaring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of a Teaching Intervention With an Advanced Practice Nurse on Quality of Life and Psychosocial and Symptom Distress in Patients With Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Transitional Care Planning
Interventions: BEHAVIORAL: telephone-based intervention|OTHER: counseling intervention|OTHER: educational intervention|OTHER: medical chart review|OTHER: questionnaire administration|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Orally Administered ENT-01 for Parkinson's Disease-Related Constipation Follow-on Safety "Roll-over" Study (Rollover)
Status: TERMINATED
Conditions: Parkinson Disease|Constipation
Interventions: DRUG: Active Investigational Treatment ENT-01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide Combined With Rituximab as Front-line Therapy for DLBCL Patients Aged Over 80 Years
Status: UNKNOWN
Conditions: Diffuse Large B Cell Lymphoma|Age Over 80 Years
Interventions: DRUG: lenalidomide combined with rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Double Blind, Randomized, Placebo Controlled, Maximal Dose Study to Determine the Safety, Tolerability of Topical Cream Containing MGC (Medical Grade Cannabis) in Healthy Volunteers
Status: COMPLETED
Conditions: Safety Study for Future Treatment of Psoriasis
Interventions: DRUG: OWC MGC cream|DRUG: OWC Control Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Preference Study of a Insulin Pen PDS290 vs. a Novo Nordisk Marketed Insulin Pen in Diabetics
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Delivery Systems
Interventions: DEVICE: FlexTouch®|DEVICE: FlexPen®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT