pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Reversal of Antipsychotic-Induced Hyperprolactinemia, Weight Gain, Hyperglycemia and Dyslipidemia
Status: UNKNOWN
Conditions: Hyperprolactinemia|Weight Gain|Dyslipidemia
Interventions: DRUG: Abilify (aripiprazole)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging of the Neural Correlates of Arousal and Awareness
Status: NOT_YET_RECRUITING
Conditions: Lesional Coma
Interventions: OTHER: Multimodal evaluation of brain function : PET-MRI, electrophysiology, eye-tracking
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Superior Labral Tear From Anterior to Posterior (SLAP) Repair Versus Biceps Tenodesis for SLAP Tears in the Shoulder
Status: TERMINATED
Conditions: SLAP Tear
Interventions: PROCEDURE: SLAP Repair|PROCEDURE: Biceps Tenodesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Use of Apixaban in Prevnetion of Thromboembolic Disease in Patients With Myeloma Trated With iMiDs
Status: UNKNOWN
Conditions: Myeloma|Venous Thromboembolism
Interventions: DRUG: Apixaban
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicentre Phase II Trial of Durvalumab Versus Physician's Choice Chemotherapy in Recurrent Ovarian Clear Cell Adenocarcinomas
Status: UNKNOWN
Conditions: Ovarian Clear Cell Carcinoma
Interventions: DRUG: durvalumab|DRUG: standard chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cellular Immunotherapy for Viral Induced Cancer - EBV Positive Lymphomas
Status: TERMINATED
Conditions: Hodgkin Lymphoma|Lymphoma, Large B-Cell, Diffuse|Post-transplant Lymphoproliferative Disorder
Interventions: BIOLOGICAL: baltaleucel-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ivabradine in Stage D Heart Failure Patients on Chronic Inotropes
Status: WITHDRAWN
Conditions: Heart Failure NYHA Class IV
Interventions: DRUG: Ivabradine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Pregabalin in Treatment of Neuropathic Pain in Patients With Idiopathic Small Fiber Neuropathy
Status: COMPLETED
Conditions: Idiopathic Small Fiber Neuropathy
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lumbar Transforaminal Epidural Dexamethasone
Status: COMPLETED
Conditions: Radicular; Neuropathic, Lumbar, Lumbosacral
Interventions: PROCEDURE: Lumbar Transforaminal Epidural Steroid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety and PET Imaging Characteristics of a Novel Senescence-specific Radiotracer [18F]FPyGal (2-[Fluorine-18]Fluoro-3-pyridinyl-β-D-galactopyranoside)
Status: UNKNOWN
Conditions: Cancer
Interventions: DRUG: [18F]FPyGal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Allogeneic Bone Marrow and T-Cell Depleted, CD34+ Peripheral Blood Stem Cell Transplantation in Patients With Aplastic Anemia
Status: UNKNOWN
Conditions: Graft Versus Host Disease|Aplastic Anemia
Interventions: DRUG: anti-thymocyte globulin|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: methylprednisolone|PROCEDURE: Allogeneic Bone Marrow Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Clinician Utilization of Corus CAD (or ASGES) in Primary Care Provider Decision Making
Status: WITHDRAWN
Conditions: Coronary Artery Disease|Angina Pectoris|Chest Pain|Cardiovascular Diseases|CAD|CVD|Coronary Heart Disease|CHD
Interventions: DIAGNOSTIC_TEST: Corus CAD (ASGES)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Association Between Time in Range and In-hospital Outcomes in Type 2 Diabetic Patients With Acute Coronary Syndrome
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus|Acute Coronary Syndrome
Interventions: DEVICE: continuous glucose monitoring system|DEVICE: capillary blood glucose monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Carbon-14-Labelled [14C] LOXO-305 (Pirtobrutinib) in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [14C]-LOXO-305|DRUG: LOXO-305|DRUG: [14C]-LOXO-305
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stool-based SDC2 DNA Methylation Test for the Detection of Colorectal Advanced Adenomatous Polyps and Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer|Colorectal Adenomatous Polyp|Screening
Interventions: DIAGNOSTIC_TEST: Stool-based SDC2 DNA methylation test|DIAGNOSTIC_TEST: Fecal immunochemical test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Peripherally Inserted Central Catheter Use for Dobutamine Infusion in Heart Failure Patients
Status: UNKNOWN
Conditions: Congestive Heart Failure
Interventions: DEVICE: peripherally inserted central catheter|DEVICE: peripherally venous access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Shear Wave Sonoelastography in the Diagnosis and Management of the Masseter Muscles Disorders
Status: UNKNOWN
Conditions: Temporomandibular Disorders
Interventions: OTHER: Stabilization occlusal splint and manual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of LiveSpo X-SECRET in SupportiveTreatment of Vaginitis
Status: RECRUITING
Conditions: Vaginitis
Interventions: DRUG: 0.9% NaCl physiological saline|COMBINATION_PRODUCT: LiveSpo X-secret
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study to Evaluate the iTotal Knee and iPoly XE Tibial Inserts
Status: TERMINATED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: iPoly XE tibial insert with ConforMIS iTotal KRS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Arts Engagement on Physical Performance, Cognition, Social Isolation, and Self-Perception in Older Adults
Status: COMPLETED
Conditions: Social Isolation|Mental Status Change|Cognitive Impairment|Physical Activity|Quality of Life|Self-Perception
Interventions: OTHER: Active Social Conversation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Incidence and Factors Associated to the Development of PICS-F Among ICU Relatives: A Longitudinal Exploratory Study
Status: RECRUITING
Conditions: Post Intensive Care Syndrome|Family Members|Caregiver Burden|Critical Illness|Mental Health|Physical Health|Cognitive Impairment|Family Satisfaction|Resilience|Social Support
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Bronchodilator on Eosinophilic Bronchitis and Cough Variant Asthma
Status: UNKNOWN
Conditions: Eosinophilic Bronchitis|Cough Variant Asthma
Interventions: DRUG: Bambuterol Hydrochloride tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupressure and Qigong in Chronic Fatigue Post COVID-19.
Status: RECRUITING
Conditions: COVID-19|Post-COVID-19 Syndrome
Interventions: OTHER: self- applied acupressure plus Qigong course plus advice literature|BEHAVIORAL: advice literature with naturopathy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Which Platelet Function Test Best Reflects the In Vivo Plasma Concentrations of Ticagrelor and Its Active Metabolite?
Status: COMPLETED
Conditions: Infarction|Myocardial Infarction|Cardiovascular Diseases|Heart Diseases|Ischemia|Myocardial Ischemia|Necrosis|Pathologic Processes|Vascular Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Collection of Immunology Specimens From Patients With Cancer or Blood Disorders, and Healthy Volunteers
Status: RECRUITING
Conditions: Healthy Subject|Hematologic and Lymphocytic Disorder|Hematopoietic and Lymphoid Cell Neoplasm|Immune System Disorder|Malignant Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Laboratory Biomarker Analysis|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study Evaluating Alterations in Thrombogenicity and Platelet Reactivity Following Lower Extremity Arthroplasty
Status: COMPLETED
Conditions: Primary Total Hip and Knee Arthroplasty
Interventions: DRUG: Arixtra|DEVICE: Pneumatic compression stockings|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2a Randomized, Double-Blind Study of Oleoyl-Estrone in Male Morbidly Obese Adults
Status: UNKNOWN
Conditions: Obesity
Interventions: DRUG: oleoyl-estrone (MP-101)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: SI-B001 Combined With Irinotecan in the Treatment of Recurrent Metastatic Esophageal Squamous Cell Carcinoma.
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinomas
Interventions: DRUG: SI-B001|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Psychological Distress Among Critical Illness Survivors and Their Caregivers
Status: COMPLETED
Conditions: Intensive Care Unit Survivors|Informal Caregivers (Family and Friends)
Interventions: BEHAVIORAL: coping skills training|OTHER: education program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Recombinant Mycobacterium Tuberculosis ESAT6-CFP10 Allergen for Children
Status: COMPLETED
Conditions: Tuberculosis Diagnosis
Interventions: BIOLOGICAL: ESAT6-CFP10 in left arm and TB-PPD in right arm|BIOLOGICAL: ESAT6-CFP10 in right arm and TB-PPD in left arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of t of the Etonogestrel Releasing Implant on Infant Growth and Development
Status: COMPLETED
Conditions: Contraception|Newborn|Child Development|Growth
Interventions: DRUG: early insertion|DRUG: conventional insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Hepatic Arterial Chemoembolization With Cisplatin or Internal Radiation Therapy in Treating Patients With Advanced Liver Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Liver Cancer
Interventions: DRUG: cisplatin|RADIATION: brachytherapy|RADIATION: yttrium Y 90 glass microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Colesevelam for the Treatment of Bile Acid Malabsorption in Patients With Crohn's Disease
Status: TERMINATED
Conditions: Crohns Disease|Bile Acid Malabsorption
Interventions: DRUG: Colesevelam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prone Positioning and Spontaneous Breathing
Status: UNKNOWN
Conditions: Critical Illness|ARDS
Interventions: PROCEDURE: Supine + spontaneous effort|PROCEDURE: Supine + paralysis|PROCEDURE: Prone + paralysis|PROCEDURE: Prone + spontaneous breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hysteroscopic Guided Endometrial Sampling: Prospective Comparison Between 5Fr and 7Fr Biopsy Forceps (HYSTEROBIO)
Status: UNKNOWN
Conditions: Biopsy
Interventions: DEVICE: Endometrial sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Randomized Trial of Incisionless Versus Conventional Laparoscopic Colectomy for Left-sided Colonic Tumors
Status: COMPLETED
Conditions: Pain,|Postoperative Wound Complication
Interventions: PROCEDURE: incisionless laparoscopic colectomy|PROCEDURE: conventional laparoscopic colectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of ACT and a Care Management App in Primary Care-based Buprenorphine Treatment
Status: RECRUITING
Conditions: Opioid-use Disorder|Chronic Pain
Interventions: BEHAVIORAL: Acceptance and commitment therapy|OTHER: Valera Smartphone Application|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of SARS-CoV-2 DNA Vaccine (ICCOV)
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: SARS-CoV-2 DNA Vaccine (ICCOV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ARCHER 1009 : A Study Of Dacomitinib (PF-00299804) Vs. Erlotinib In The Treatment Of Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Dacomitinib (PF-00299804)|DRUG: Active Comparator (erlotinib)|DRUG: Placebo erlotinib|DRUG: Placebo PF00299804
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Localization of Anatomical Structures Involved in Nodal Tachycardias by High Density Mapping.
Status: RECRUITING
Conditions: Atrioventricular Nodal Reentry Tachycardia|Supraventricular Tachycardia
Interventions: PROCEDURE: high resolution cartography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: [11C]5-Hydroxy-tryptophan PET for Assessment of Islet Mass in Type 2 Diabetes
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: RADIATION: Positron emission tomography with the tracer [11C]5-hydroxy-tryptophan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Qutenza Patch as Treatment for Disabling Treprostinil (Remodulin) Infusion Site Pain
Status: COMPLETED
Conditions: Pulmonary Hypertension|Pulmonary Arterial Hypertension
Interventions: DRUG: Qutenza (8% capsaicin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interaction Study in Patients With Pulmonary Hypertension and Stable Treatment of Sildenafil 20 mg TID
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Riociguat (Adempas, BAY63-2521)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor Transplant
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Bone Marrow Failure|Immunodeficiencies|Histiocytosis|Sickle Cell Disease|Beta Thalassemia|Inborn Errors of Metabolism
Interventions: DRUG: Full Intensity with TBI|DRUG: Full Intensity|DRUG: Reduced Intensity|DRUG: Reduced Intensity (Fanconi)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Involvement of Skeletal Muscle Fibrocytes in sarcOpenia in Patients With Chronic ObstRuctive Pulmonary Disease
Status: RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: PROCEDURE: quadricipital biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Grasp-Release Assessment of a Networked Neuroprosthesis Device
Status: RECRUITING
Conditions: Spinal Cord Injury at C5-C7 Level|Spinal Cord Injuries|Spinal Cord Injury Cervical
Interventions: DEVICE: Networked Neuroprosthesis Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cross-cultural Adaptation, Reliability and Validity of the Turkish Version of the Headache Disability Questionnaire
Status: RECRUITING
Conditions: Headache|Headache Disorders|Headache, Migraine|Headache, Tension|Headaches Chronic|Headaches Muscular
Interventions: OTHER: Survey study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EMLA Cream as Analgesic for Outpatient Gynecological Procedures
Status: ENROLLING_BY_INVITATION
Conditions: Pain
Interventions: DRUG: EMLA Cream|DRUG: VersaPro Cream Base for Compounding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of a New Treatment Program for Adolescents With Eating Disorders: MINERVA Program
Status: RECRUITING
Conditions: Eating Disorders in Adolescence|Anorexia Nervosa|Bulimia Nervosa|Binge-Eating Disorder|Other Specified Feeding or Eating Disorder
Interventions: BEHAVIORAL: ED-MINERVA Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of DWP14012 in Patients With Acute or Chronic Gastritis
Status: COMPLETED
Conditions: Acute Gastritis|Chronic Gastritis
Interventions: DRUG: DWP14012 X mg|DRUG: DWP14012 X mg placebo|DRUG: DWP14012 Y mg|DRUG: DWP14012 Y mg placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 4-Aminopyridine, Atenolol, or Placebo in Patients With Vestibular Migraine
Status: WITHDRAWN
Conditions: Vestibular Migraine|Migraine Disorders|Vestibular Diseases
Interventions: DRUG: 4-aminopyridine|DRUG: Atenolol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Learn Whether Regorafenib in Combination With Nivolumab Can Improve Tumor Responses and How Safe it is for Participants With Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Regorafenib, (Stivarga, BAY73-4506)|DRUG: Nivolumab (Opdivo)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thymoglobuline in Non-myeloablative Allogeneic Stem-cell Transplantation
Status: COMPLETED
Conditions: Stem Cell Transplantation|Graft Vs Host Disease
Interventions: DRUG: Thymoglobuline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Obesity on the Pharmacokinetics of Imipenem-Relebactam in ICU Patients
Status: ENROLLING_BY_INVITATION
Conditions: Obesity|Critical Illness
Interventions: DRUG: Imipenem/Cilastatin/Relebactam 1.25g
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Long-term Persistence of Hepatitis B and Pertussis Antibody Responses in Healthy 4 to 5 Year Old Children Previously Vaccinated With Vaxelis® or INFANRIX® Hexa (V419-012)
Status: COMPLETED
Conditions: Hepatitis B|Pertussis
Interventions: OTHER: Blood Sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Thora-3Di™ Respiratory Rate Validation
Status: UNKNOWN
Conditions: Pulmonary Disease
Interventions: DEVICE: Structured Light Plethysmography (Thora-3Di)|DEVICE: BCI Capnograph 9004 (Smiths Medical)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of TLBZT Based Herbal Therapy Plus Chemotherapy for Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Chemotherapy|DRUG: Herbal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing the Use of Remifentanil Versus Propofol for Performing Bronchial Fibroscopy
Status: COMPLETED
Conditions: Realisation of Bronchial Fibroscopy
Interventions: DRUG: 1: Remifentanil|DRUG: 2: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Cyclophosphamide Versus Methylprednisolone in Patients With Secondary Progressive Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Chronic Progressive
Interventions: DRUG: Cyclophosphamide (drug)|DRUG: Methylprednisolone (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Garcinia Mangostana L Rind and Solanum Lycopersicum Fructus Trial to Prevent Exercise-induced Oxidative Stress
Status: UNKNOWN
Conditions: Exertion; Excess|Oxidative Stress
Interventions: DRUG: Garcinia-mangostana-L-rind and Solanum-Lycopersicum-Fructus mixture-extract|DRUG: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Supralottic Airway Devicess on Optic Nerve Sheath Diameter
Status: COMPLETED
Conditions: Intracranial Pressure Increase|Supraglottic Airway Device|Optic Nerve Sheath Diameter
Interventions: OTHER: pLMA: PROSEAL LARYNGEAL MASK, sLMA : SUPREMA LARYNGEAL MASK, I-jel =I-GEL
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PD-1 Antibody SHR-1210 Combined With Apatinib of First-line Treatment of Advanced Acral Melanoma
Status: UNKNOWN
Conditions: Melanoma
Interventions: DRUG: SHR1210|DRUG: apatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Grazoprevir (MK-5172) + Elbasvir (MK-8742) + Ribavirin in Participants With Chronic Hepatitis C Who Failed Prior Direct-Acting Antiviral Therapy (MK-5172-048)
Status: COMPLETED
Conditions: Hepatitis C Virus
Interventions: DRUG: Grazoprevir (GZR)|DRUG: Elbasvir (EBR)|DRUG: Ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI-Eye Tracking Pairing, a Tool for Assessing Social Cognition in Children With ASD
Status: RECRUITING
Conditions: ASD|Functional Magnetic Resonance Imaging|Eye Tracking|Social Cognition|Joint Attention
Interventions: OTHER: MRI-ET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: R-5280 in Newly Diagnosed Patients With Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes|Type 1 Diabetes (Juvenile Onset)|Diabetes Mellitus, Type 1
Interventions: DRUG: R-5280|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of DKN-01 in Combination With Paclitaxel or Pembrolizumab
Status: COMPLETED
Conditions: Esophageal Neoplasms|Adenocarcinoma of the Gastroesophageal Junction|Gastroesophageal Cancer|Squamous Cell Carcinoma|Gastric Adenocarcinoma
Interventions: DRUG: DKN-01 150 mg|DRUG: Paclitaxel|DRUG: Pembrolizumab|DRUG: DKN-01 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RL-MPV Followed by BBC HCT Using Autologous Stem Cells and Maintenance Therapy With Nivolumab for Newly Diagnosed PCNSL
Status: RECRUITING
Conditions: Primary CNS Lymphoma
Interventions: DRUG: Rituximab, Methotrexate, Vincristine, Procarbazine, Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Ability of Zoledronic Acid to Reduce the Rate of Subsequent Osteoporotic Fractures After a Hip Fracture
Status: COMPLETED
Conditions: Osteoporosis|Hip Fracture
Interventions: DRUG: Zoledronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Ondansetron Administered as IR (Zofran) and MR (EUR1025)
Status: COMPLETED
Conditions: Nausea
Interventions: DRUG: EUR-1025|DRUG: EUR-1025|DRUG: EUR-1025|DRUG: EUR-1025
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Cognitive, Neuropsychiatric and Functional Outcomes in Adults Who Have Received Chimeric Antigen-Receptor T-Cell (CAR-T) Therapy for Aggressive Lymphoma at Stanford
Status: NOT_YET_RECRUITING
Conditions: Non Hodgkin Lymphoma
Interventions: BEHAVIORAL: Neuropsychological testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MethylphenIdate for Fatigue in Haematological Cancer
Status: UNKNOWN
Conditions: Hematological Cancer
Interventions: DRUG: Methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Normothermic Machine Perfusion: an Additional Value for Kidney Transplant Outcomes?
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Transplant Failure|Chronic Kidney Failure
Interventions: PROCEDURE: Normothermic machine perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Placebo Controlled Study of MR901 (Talaporfin Sodium Sodium + a Drug-activating Device) for the Relief of Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: talaporfin sodium|DRUG: Saline|DEVICE: Drug Activator 100 J/cm|DEVICE: Drug Activator 200 J/cm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of Cetrotide® Gonadotropin-releasing Hormone Antagonist (GnRH Antagonist) With GONAL-f® in Assisted Reproductive Technologies (ART)
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Cetrorelix acetate and Follitropin alfa
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase III Study of Envafolimab Versus Placebo Plus Chemotherapy in Resectable Stage III NSCLC
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Envalfolimab subcutaneously injected+Platinum-based doublet chemotherapy intravenous injection|DRUG: placebo subcutaneously injected +Platinum-based doublet chemotherapy intravenous injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ARO-HSD in Healthy Volunteers and Patients With Non-Alcoholic Steatohepatitis (NASH) or Suspected NASH
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis
Interventions: DRUG: ARO-HSD Injection|DRUG: sterile normal saline (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lactobacillus Plantarum in Preventing Acute Graft Versus Host Disease in Children Undergoing Donor Stem Cell Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic and Lymphoid System Neoplasm|Leukemia|Lymphoma
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|BIOLOGICAL: Lactobacillus plantarum strain 299|BIOLOGICAL: Lactobacillus plantarum strain 299v|OTHER: Placebo Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: SBRT + PD-1/PDL-1 Inhibiting Therapy for Advanced Solid Tumors After Dz Control on PD-1/PDL-1 Tx
Status: COMPLETED
Conditions: Solid Tumor
Interventions: RADIATION: Stereotactic radiotherapy|OTHER: Biological: humanized anti-PD-1 monoclonal antibody|OTHER: Biological: humanized anti-PD-L1 monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double-masked Study of PG324 Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: PG324 Ophthalmic Solution 0.02%/0.005%|DRUG: Netarsudil (AR-13324) ophthalmic solution 0.02%|DRUG: Latanoprost ophthalmic solution 0.005%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Follow-up of Incisional Hernia Repaired With Intraperitoneal Mesh
Status: COMPLETED
Conditions: Incisional Hernia
Interventions: DEVICE: Implant of a prosthetic mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychometric Properties of the International Trauma Interview (ITI) for ICD-11 PTSD and CPTSD
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder (PTSD)|Complex Post-Traumatic Stress Disorder (CPTSD)
Interventions: DIAGNOSTIC_TEST: International Trauma Interview (ITI) for ICD-11 PTSD and Complex PTSD - German version
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Plerixafor Combined With Cytarabine and Daunorubicin in Patients With Newly Diagnosed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Application of a New Ovarian Stimulation Protocol in IVF
Status: UNKNOWN
Conditions: Clinical Pregnancy Rate|Ovulation Induction
Interventions: DRUG: GnRH-a|DRUG: GnRH-a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Treatment With Yellow Micropulse Laser and Green Conventional Laser in Diabetic Macular Edema
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: DEVICE: Micropulse laser treatment|DEVICE: Laser modified ETDRS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Fosaprepitant in Preventing Chemotherapy-induced Vomiting in Children Treated With Medium and High Emetic Chemotherapeutic Drugs
Status: UNKNOWN
Conditions: Chemotherapy Induced Nausea and Vomiting Pediatric Cancer Patients
Interventions: DRUG: Fosaprepitant|DRUG: Placebo(normal saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antioxidants as Adjuvant Therapy to Standard Therapy in Patients With COVID-19
Status: COMPLETED
Conditions: Pneumonia, Viral|Covid19|ARDS|Oxidative Stress
Interventions: DRUG: Vitamin C|DRUG: Vitamin E|DRUG: Melatonin|DRUG: N-acetyl cysteine|DRUG: Pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Methods of Administration of a PEG Solution
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: PEG solution in a single dose of 3 liters|DRUG: PEG solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plantarflexion Reduces Urgency and Peak Detrusor Pressure in Patients With Detrusor Overactivity
Status: COMPLETED
Conditions: Overactive Detrusor
Interventions: BEHAVIORAL: Plantarflexion 2nd wave|BEHAVIORAL: Plantarflexion - 3rd wave
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paracetamol, Dexketoprofen and Ibuprofen In Non-Traumatic Acute Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain, Mechanical
Interventions: DRUG: Paracetamol|DRUG: Dexketoprofen|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess the Functionality of Female Condom With a Silicone Elastomer Vaginal Ring
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: COMBINATION_PRODUCT: Silicone Elastomer Vaginal Ring|DEVICE: Female Condom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Structured Tailored Rehabilitation After Hip Fragility Fracture
Status: RECRUITING
Conditions: Hip Fractures
Interventions: OTHER: Low-risk subgroup|OTHER: Medium-risk subgroup|OTHER: High-risk subgroup|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of 99mTc-glucarate to Detect Acute Coronary Syndrome in Chest Pain Patients.
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: 99mTc-glucarate solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma
Interventions: DRUG: cilengitide|DRUG: temozolomide|RADIATION: radiation therapy|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Equivalence of the Skin Prick Test Tape vs. Conventional Skin PrickTest
Status: UNKNOWN
Conditions: Allergic Rhinitis|Allergic Asthma|Allergic Conjunctivitis|Food Allergy
Interventions: DIAGNOSTIC_TEST: Skin Prick Test|DIAGNOSTIC_TEST: Skin Prick Test TAPE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Intravitreal REGN2176-3 in Participants With Neovascular ("Wet") Age-Related Macular Degeneration (AMD)
Status: TERMINATED
Conditions: Neovascular Age-Related Macular Degeneration
Interventions: DRUG: REGN2176-3|DRUG: Intravitreal Aflibercept Injection (IAI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MS-20 on Gut Microbiota and Risk/Severity of Cachexia in Pancreatic Cancer Patients
Status: RECRUITING
Conditions: Pancreatic Cancer|Cachexia|Chemotherapy Effect
Interventions: DRUG: MS-20|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Safety and Efficacy of JP-1366 in Patients With Erosive Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: GERD
Interventions: DRUG: JP-1366|DRUG: JP-1366 placebo|DRUG: Esomeprazole 40mg|DRUG: Esomeprazole placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid Rituximab Infusion at 90-minute Among Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Non Hodgkin Lymphoma
Interventions: DRUG: Rituximab (Mabthera®, Roche Pty Ltd, Basel, Switzerland)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Epilepsy Medication Valproate Administered Via ICV Route and Catheters and Pumps for CSF Infusion
Status: TERMINATED
Conditions: Focal Epilepsy
Interventions: DRUG: Valproic Acid delivered to ICV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension to a Study on the Efficacy and Safety of Vildagliptin in Combination With Pioglitazone in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: vildagliptin|DRUG: pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of MAR001 in Adults With Metabolic Dysfunction
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertriglyceridemia
Interventions: DRUG: MAR001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Low Sodium Intake on the Anti-proteinuric Efficacy in Hypertensive Patient With Olmesartan
Status: COMPLETED
Conditions: Hypertension|Chronic Kidney Disease|Microalbuminuria
Interventions: BEHAVIORAL: Intensive education of low salt diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reintroduction Regimens After Hepatitis During Anti-tuberculosis Treatment
Status: UNKNOWN
Conditions: Hepatitis|Tuberculosis, Pulmonary
Interventions: DRUG: isoniazid, rifampin, pyrazinamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment With Immune Checkpoint Inhibition (ICI) in Patients With Newly Diagnosed Glioblastoma or Gliosarcoma
Status: RECRUITING
Conditions: Glioblastoma|Gliosarcoma|Malignant Glioma
Interventions: DRUG: TMZ|DRUG: ipilimumab 3mg/kg|DRUG: Nivolumab|DRUG: ipilimumab 1mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Quadrivalent Influenza Vaccine Administered Intramuscularly in Children/Adolescents and Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Quadrivalent Influenza Vaccine (split virion, inactivated)|BIOLOGICAL: Quadrivalent Influenza Vaccine (split virion, inactivated)|BIOLOGICAL: Quadrivalent Influenza Vaccine (split virion, inactivated)|BIOLOGICAL: 2011 to 2012 Trivalent Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: BCMA Nano Antibody CAR-T Cells for Patients With Refractory and Relapsed Multiple Myeloma
Status: UNKNOWN
Conditions: Relapsed and Refractory Multiple Myeloma
Interventions: BIOLOGICAL: BCMA CAR-T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmaco-epidemiological Study of Short Patients Born Small for Gestational Age (SGA), Treated With Saizen® (Recombinant Somatropin)
Status: COMPLETED
Conditions: Infant, Small for Gestational Age
Interventions: DRUG: recombinant somatropin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of IQP-AK-102 in Reducing Appetite
Status: COMPLETED
Conditions: Weight Loss|Appetite Modulation (Focus of Study)
Interventions: DEVICE: IQP-AK-102|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravascular Ultrasound-Guided Intervention for Venous Leg Ulcers (IGuideU)
Status: TERMINATED
Conditions: Venous Ulcer of Leg
Interventions: DIAGNOSTIC_TEST: IVUS|OTHER: Continued Compression Therapy/Stockings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: StrataGraft® Skin Tissue as an Alternative to Autografting Full-thickness Complex Skin Defects
Status: TERMINATED
Conditions: Trauma-related Wound|Burns|Skin Wound
Interventions: BIOLOGICAL: StrataGraft Skin Tissue|PROCEDURE: Autograft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Study Evaluating the Safety and Tolerability of LJM716, BYL719 and Trastuzumab in Patients With Metastatic HER2+ Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: BYL719|DRUG: LJM716|DRUG: TRASTUZUMAB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of JECEVAX in Young Children
Status: COMPLETED
Conditions: Japanese Encephalitis
Interventions: BIOLOGICAL: JEVAX|BIOLOGICAL: JECEVAX-1|BIOLOGICAL: JECEVAX-0.8|BIOLOGICAL: JECEVAX-0.5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Normothermiс Cardiopulmonary Bypass Increases Cerebral Oxygenation During Valve Surgery
Status: COMPLETED
Conditions: Heart Valve Diseases
Interventions: DEVICE: hypothermic CPB|DEVICE: normothermic CPB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Freezing of Gait in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: Tower of Hanoi|OTHER: Placebo group - non use of Tower of Hanoi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of MK-4166 and MK-4166 in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-4166-001)
Status: COMPLETED
Conditions: Solid Tumor
Interventions: BIOLOGICAL: MK-4166|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial Evaluate the Safety and Tolerability Profile of HPV Vaccine
Status: COMPLETED
Conditions: Human Papillomavirus Infection
Interventions: BIOLOGICAL: Recombinant Nonavalent (Types 6/11/16/18/31/33/45/52/58) Human Papillomavirus (HPV) Vaccine (Escherichia Coli)|BIOLOGICAL: Recombinant nonavalent Human Papillomavirus (Types 6,11,16,18,31,33,45,52,58) Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cisplatin or Carboplatin, and Etoposide With or Without Sunitinib Malate in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Extensive Stage Lung Small Cell Carcinoma|Recurrent Lung Small Cell Carcinoma
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Etoposide|OTHER: Laboratory Biomarker Analysis|OTHER: Placebo Administration|DRUG: Sunitinib Malate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Breathing Exercises to Improve Fatigue and Quality of Life in Hemodialysis Patients
Status: COMPLETED
Conditions: Hemodialysis|Breathing Exercises|Fatigue
Interventions: OTHER: Breathing exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Contribution of Online Stress and Pain Mindfulness Treatment to ACT Process Change and Outcomes in Chronic Pain
Status: ENROLLING_BY_INVITATION
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Breathworks Mindfulness (Health or Stress Arm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT