pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Low-temperature Radiofrequency Coblation Micro-tenotomy for the Treatment of Achilles Tendinopathy
Status: NOT_YET_RECRUITING
Conditions: Achilles Tendinopathy
Interventions: RADIATION: Radiofrequency coblation micro-tenotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Anesthesia Depth Increases the Degree of Postoperative Dementia, Delirium, and Cognitive Dysfunction
Status: COMPLETED
Conditions: Anesthesia|Delirium|Dementia|Bispectral Index Monitor
Interventions: DEVICE: Anesthesia depth monitor|DEVICE: Sham control|DRUG: propofol and sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Profile HaloTM Mixed Fractional Laser on Treating of Facial and Neck Photoaging.
Status: COMPLETED
Conditions: Photoaging
Interventions: RADIATION: Profile HaloTM Mixed Fractional Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HIPACE High Frequency Low Energy Pacing to Terminate Fast Ventricular Arrythmias
Status: COMPLETED
Conditions: Arrhythmias
Interventions: DEVICE: Cardiac Resynchronisation Defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension
Status: COMPLETED
Conditions: Liver Diseases|Portal Hypertension
Interventions: DRUG: SHAPE measurement (Sonazoid ultrasoud contrast agent)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Sipjeondaebo-tang on Korean Patients With Cold Hypersensitivity in the Hands and Feet (SDT)
Status: COMPLETED
Conditions: Cold Hypersensitivity
Interventions: DRUG: Sipjeondaebo-tang Granule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Water Assisted Colonoscopy vs Air Insufflation on Resident Training
Status: ENROLLING_BY_INVITATION
Conditions: Water Assisted Colonoscopy
Interventions: PROCEDURE: Water-only infusion technique|PROCEDURE: Water infusion and air insufflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Dexmedetomidine Improves the Surgical Field and Postoperative Recovery of Nasal Endoscopic Surgery
Status: COMPLETED
Conditions: Dexmedetomidine|Bleeding|Surgical Field
Interventions: DRUG: IV administration of DEX to investigate the effects for functional nasal endoscopic surgery|DRUG: IV administration of Midazolam to investigate the effects for functional nasal endoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Outcomes of HCC (Hepatocellular Carcinoma) Patients Treated With TACE (Transarterial Chemoembolization) and Early, Not Early or Not at All Followed by Sorafenib
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: PROCEDURE: TACE (transarterial chemoembolization)|DRUG: Sorafenib (Nexavar, BAY43-9006)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial of Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Oxygen in Women Having Planned Caesarean Delivery
Status: COMPLETED
Conditions: Pre-oxygenation in Term Pregnant Women
Interventions: DEVICE: THRIVE pre-oxygenation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intrathecal Morphine in Knee Arthroplasty
Status: COMPLETED
Conditions: Pain, Postoperative|Arthroplasty, Replacement, Knee
Interventions: DRUG: intra thecal morphine|DRUG: intra thecal morphine|DRUG: intra thecal morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of TKAs Using Force Plate Analysis
Status: UNKNOWN
Conditions: Knee Osteoarthritis|Total Knee Arthroplasty|Knee Injuries|Knee Arthritis
Interventions: DEVICE: MicroPort Orthopedics EVOLUTION Medial Pivot TKA|DEVICE: Depuy Synthes ATTUNE PCR TKA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Vancomycin in Comarison With Cefazolin in Prevention of SSI After Craniotomy
Status: UNKNOWN
Conditions: Elective Craniotomy-candidated Patients
Interventions: DRUG: Vancomycin|DRUG: Cefazolin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Remote Ischaemic Preconditioning on Clinical Outcomes in CABG Surgery
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: PROCEDURE: Remote ischaemic preconditioning|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combined Hydrodilatation, Corticosteroid Injection, and Joint Mobilization for Treament of Frozen Shoulder
Status: COMPLETED
Conditions: Frozen Shoulder|Hydrodilatation|Joint Mobilization|Corticosteroid Injection|Physical Therapy|Rehabilitation
Interventions: PROCEDURE: Comb group|PROCEDURE: PT group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biological, Pathological and Imagery Markers in the First-line Treatment of Metastatic Clear-cell Renal Cell Carcinoma
Status: TERMINATED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Sunitinib (SUTENT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telehealth Intervention for Improved Blood Pressure Control With Targeted Incentives
Status: COMPLETED
Conditions: Hypertension|Non-Adherence, Patient
Interventions: BEHAVIORAL: Wellth Smartphone App|BEHAVIORAL: Targeted Incentives|BEHAVIORAL: Non-Restricted Incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Characterizing the Incretin Effect of Amino Acids and Defining GLP-1 Role on Skeletal Muscle
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DRUG: GLP-1|DRUG: Insulin Actrapid|DIETARY_SUPPLEMENT: Oral amino acids|DRUG: GIP|DRUG: Intravenous amino acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Performance of the CARDIOGARD Cannula
Status: UNKNOWN
Conditions: Heart Valve Diseases|Coronary Artery Disease
Interventions: DEVICE: CardioGard Cannula|DEVICE: 22Fr curved Cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Topical Absorption of Glutathione-cyclodextrin Complex in Healthy Human Subjects Improves Immune Response Against Mycobacterium Infection
Status: COMPLETED
Conditions: Glutathione-cyclodextrin Complex Absorption
Interventions: DIETARY_SUPPLEMENT: Glutaryl Solution|DIETARY_SUPPLEMENT: Placebo Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study on the Role of Hormonal Treatment for Two Dosage Levels of Prostate Radiation Therapy Versus Prostate Radiation Therapy Alone
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: RADIATION: Radiotherapy 70 Gy|RADIATION: Radiotherapy 76 Gy|DRUG: Androgen blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Cohort Study of HPV Viral Load in Predicting the Postoperative Recurrence of HSIL
Status: RECRUITING
Conditions: HPV Infection|HSIL, High-Grade Squamous Intraepithelial Lesions|Viral Load
Interventions: OTHER: Follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: AbataCept for the Treatment of Immune-cHeckpoint Inhibitors Induced mYocarditiS
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocarditis
Interventions: DRUG: Abatacept 250 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Sonelokimab for the Treatment of Patients With Active Psoriatic Arthritis
Status: COMPLETED
Conditions: Arthritis, Psoriatic
Interventions: DRUG: Sonelokimab|DRUG: Placebo|DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial of Oral Metronomic Topotecan and Oral Pazopanib to Treat Recurrent/Persistent Gynecologic Tumors
Status: COMPLETED
Conditions: Gynecologic Tumors
Interventions: DRUG: Oral Topotecan|DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perceived Stress and Negative Thoughts With Biomarkers in People With Type 2 Diabetes Mellitus and Healthy Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Guilty feelings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Left Ventricular Function After Acute Myocardial Infarction (AMI). Treatment With Angiotensin 2-Receptor Blockade (GLOBAL-Study)
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Irbesartan Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Low-Intensity Conditioning for Allogeneic Stem Cell Transplant
Status: COMPLETED
Conditions: Multiple Myeloma|Lymphocytic Leukemia, Chronic|Lymphoma, Low-Grade
Interventions: PROCEDURE: Reduced intensity conditioning|PROCEDURE: Rapid immunosuppressive taper|PROCEDURE: Prophylactic donor leukocyte infusions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-assisted CNSs Mapping Versus Dual-tracer-guided Sentinel Lymph Node Biopsy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: UC group: ultrasound-assisted CNSs guided|PROCEDURE: GC group: CNSs plus ICG dual-tracer-guided
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computerization of Medical Practices for the Enhancement of Therapeutic Effectiveness (COMPETE III)
Status: COMPLETED
Conditions: Vascular Diseases
Interventions: BEHAVIORAL: Vascular Management Program|BEHAVIORAL: Clinical Care Coordinators|BEHAVIORAL: Web-based Vascular Tracker for Patient and Physician|BEHAVIORAL: Automated Telephone Reminder System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study of the Effects of Amprenavir, a Protease Inhibitor, on Carbohydrate and Fat Metabolism in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Abacavir sulfate|DRUG: Amprenavir|DRUG: Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare the Efficacy and Safety of HLX04-O With Ranibizumab in Subjects With wAMD
Status: UNKNOWN
Conditions: Age Related Macular Degeneration
Interventions: DRUG: HLX04-O，recombinant anti-vascular endothelial growth factor (VEGF) humanized monoclonal antibody ophthalmic injection|DRUG: Lucentis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: P38 Mitogen-activated Protein (Map) Kinase Inhibitor (SB-681323)Study In Patients With Neuropathic Pain
Status: COMPLETED
Conditions: Pain, Neuropathic
Interventions: DRUG: SB681323|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Toripalimab Plus Radiotherapy in Patients With Operable Stage II-IIIA (N+) Non Small Cell Lung Cancer
Status: RECRUITING
Conditions: NSCLC
Interventions: RADIATION: SBRT+LDRT|DRUG: Toripalimab|DRUG: Chemotherapy drug|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Incorporating Tai Chi in Pulmonary Rehabilitation Program for Chronic Obstructive Pulmonary Disease Patients in Primary Health Care
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Tai chi + PRP|OTHER: PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wyeth Study To Evaluate a 13-valent Pneumococcal Conjugate Vaccine in Infants
Status: COMPLETED
Conditions: Pneumococcal Vaccines
Interventions: BIOLOGICAL: 13-valent Pneumococcal Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Study of VLX-1005 in Healthy Subjects
Status: COMPLETED
Conditions: Safety and Tolerability in Healthy Volunteers
Interventions: DRUG: VLX-1005|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial for Chlorhexidine as Treatment for Vulvovaginal Candidiasis
Status: RECRUITING
Conditions: Candidiasis, Vulvovaginal
Interventions: DRUG: Chlorhexidine Gluconate|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Extension Study to Evaluate the Safety of Dutogliptin/PHX1149T in Subjects With Type 2 Diabetes Mellitus
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: dutogliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Mulligan Mobilization With Movement as Compared to Kaltenborn Joint Mobilization in the Management of Knee Osteoarthritis
Status: ENROLLING_BY_INVITATION
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Heating pad|DEVICE: Transcutaneous electrical nerve stimulation(TENS)|PROCEDURE: Mulligan mobilization with movement (MWM)|PROCEDURE: Kaltenborn joint mobilization|PROCEDURE: Resistance Training exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Investigate the Non-inferiority of Pegloticase Administered Every 4 Weeks (Q4W) With MTX Compared With Every 2 Weeks (Q2W) With MTX in Participants With Uncontrolled Refractory Gout
Status: RECRUITING
Conditions: Gout
Interventions: BIOLOGICAL: Pegloticase|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HEALEY ALS Platform Trial - Regimen C CNM-Au8
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: CNM-Au8|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Consuming Modified Plant Seed Oil Containing Fish Oil Fatty Acids Act in the Same Way as Consuming Fish Oil?
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Single dose fish oil|DIETARY_SUPPLEMENT: Repeated dose fish oil|DIETARY_SUPPLEMENT: single dose Camelina seed oil|DIETARY_SUPPLEMENT: repeated dose camelina seed oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mandibular Furcation II Regeneration
Status: TERMINATED
Conditions: Furcation Defects|Periodontal Diseases
Interventions: DEVICE: Biphasic calcium phosphate (Straumann Bone Ceramic) + collagen membrane (Straumann Jason Membrane)|DRUG: Biphasic calcium phosphate (Straumann Bone Ceramic) + enamel matrix proteins (Straumann Emdogain)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant Candidates
Status: RECRUITING
Conditions: Liver Transplant
Interventions: DRUG: CMV-MVA Triplex|DRUG: Placebo for CMV-MVA Triplex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EMPAgliflozin in Heart Failure With PReserved Ejection Fraction and End Stage Renal Disease
Status: NOT_YET_RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction|End Stage Renal Disease on Dialysis
Interventions: DRUG: Empagliflozin 25 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: EpCAM CAR-T for Treatment of Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Neoplasm of Nasopharynx TNM Staging Distant Metastasis (M)|Breast Cancer Recurrent|Gastric Cancer With Metastasis
Interventions: BIOLOGICAL: EpCAM CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Metformin, Pegylated Interferon Alpha and Ribavirin for Chronic Hepatitis C With Insulin Resistance
Status: UNKNOWN
Conditions: Chronic Hepatitis c|Insulin Resistance
Interventions: DRUG: metformin|DRUG: pegylated-IFN|DRUG: ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clearing Lungs With Epithelial Sodium Channel (ENaC) Inhibition in Cystic Fibrosis (CF)
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: P-1037|DRUG: Hypertonic Saline|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Respiratory Exercises on Pain and Functionality in Individuals With Rotator Cuff Syndrome
Status: COMPLETED
Conditions: Rotator Cuff Syndrome
Interventions: OTHER: Conventional Treatment|OTHER: Respiratory Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Afrezza® Dosing Optimization Study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: COMBINATION_PRODUCT: Afrezza Dose 1|COMBINATION_PRODUCT: Afrezza Dose 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PeRsonalizing the Approach to the Oncologic Frail Individual Through Tailored Assessment and Intervention (PROFIT Study)
Status: UNKNOWN
Conditions: Older Adults|Gastro-Intestinal Cancer|Prostate Cancer|Lung Cancer|Frail Elderly Syndrome
Interventions: BEHAVIORAL: Intervention group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phenotype, Genotype & Biomarkers in ALS and Related Disorders
Status: ENROLLING_BY_INVITATION
Conditions: Amyotrophic Lateral Sclerosis|Frontotemporal Dementia|Primary Lateral Sclerosis|Hereditary Spastic Paraplegia|Progressive Muscular Atrophy|Multisystem Proteinopathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Size of Gastric Sleeve on the Weight Loss. Correlation With Gastric Function and Endocrine-metabolic Changes.
Status: UNKNOWN
Conditions: Obesity, Morbid
Interventions: PROCEDURE: Bougie Size 33 Fr|PROCEDURE: Bougie Size 42 Fr|PROCEDURE: Distance pylorus 2 cm|PROCEDURE: Distance pylorus 5 cm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual Acupoints Stimulation Alleviates Pulmonary Complication
Status: UNKNOWN
Conditions: Pulmonary Complication|Postoperative Complications
Interventions: DEVICE: acupoint stimulation|DEVICE: no treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adrenal Artery Ablation for Primary Aldosteronism
Status: UNKNOWN
Conditions: Primary Aldosteronism|Hypertension
Interventions: PROCEDURE: Endovascular chemical Ablation of Adrenal Gland|DRUG: Sequenced antihypertensvie drugs with titrated dosage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Efficacy of Bixdo Ultra Compact Water Flosser
Status: NOT_YET_RECRUITING
Conditions: Plaque Induced Gingivitis
Interventions: DEVICE: Bixdo Ultra Compact Water Flosser|DEVICE: Manual toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3Mixtatin Versus Modified 3Mix-MP in Lesion Sterilization and Tissue Repair for Treatment of Necrotic Primary Molars
Status: NOT_YET_RECRUITING
Conditions: Necrotic Primary Molars
Interventions: DRUG: 3Mixtatin paste: Simvastatin mixed with modified triple antibiotic|DRUG: 3Mix: Modified triple antibiotic mix in propylene glycol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does a Nursing Intervention Improve Adherence to Oral Chemotherapies in the Outpatient Cancer Treatment Setting?
Status: UNKNOWN
Conditions: Antineoplastic Agents
Interventions: BEHAVIORAL: weekly telephone follow up|BEHAVIORAL: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Left Ventricular Septal Pacing: Potential Application for Cardiac Resynchronization Therapy
Status: UNKNOWN
Conditions: Heart Failure|Cardiac Resynchronization Therapy|Left Bundle-Branch Block
Interventions: DEVICE: Cardiac resynchronization therapy (CRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sodium Salicylate in Treating Patients With Advanced Myelodysplastic Syndrome, Acute Myelogenous Leukemia, or Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: DRUG: sodium salicylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Double Low-Dose" DECT for HCC Imaging
Status: COMPLETED
Conditions: HCC
Interventions: DIAGNOSTIC_TEST: Double Low-Dose protocol CT|DIAGNOSTIC_TEST: Standard protocol CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Microbiota Modification for the Treatment of Motor Complication of Parkinson´s Disease
Status: COMPLETED
Conditions: Parkinson's Disease Aggravated
Interventions: DRUG: sodium phosphate enema, oral rifaximin and polyethylene glycol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3502970 in Japanese Participants With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY3502970|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immunogenicity and Safety of a Tetanus-diphtheria Vaccine and a 13-valent Pneumococcal Conjugate Vaccine
Status: COMPLETED
Conditions: Tetanus|Diphtheria|Pneumococcal Infections
Interventions: BIOLOGICAL: Tetanus-diphtheria (Td) and PCV13|BIOLOGICAL: PCV13 alone|BIOLOGICAL: Td alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Methylphenidate vs. Risperidone for the Treatment of Children and Adolescents With ADHD and Disruptive Disorders
Status: TERMINATED
Conditions: Attention Deficit/Hyperactivity Disorder|Oppositional Defiant Disorder|Conduct Disorder
Interventions: DRUG: Methylphenidate|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor
Status: NOT_YET_RECRUITING
Conditions: Patients With Non-Small Cell Lung Cancer
Interventions: DRUG: OSE2101|DRUG: Docetaxel|DEVICE: NGS HLAA2 assay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 10mg ZD4054 (Zibotentan) PK Study in Male, Elderly Chinese Patients With Advanced Solid Malignancies
Status: COMPLETED
Conditions: Advanced Solid Malignancies
Interventions: DRUG: ZD4054 (Zibotentan)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Pharmacokinetics (PK), Safety, and Efficacy of B/F/TAF in Human Immunodeficiency Virus (HIV)-1 Infected, Virologically Suppressed, Pregnant Women in Their Second and Third Trimesters
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: DRUG: B/F/TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SmartCare: Innovations in Caregiving Interventions
Status: COMPLETED
Conditions: Primary Malignant Brain Tumors
Interventions: BEHAVIORAL: CAU+ (Enhanced Care as Usual)|BEHAVIORAL: Beating the Blues|BEHAVIORAL: SmartCare
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness and Safety of LIVIA® Transcutaneous Electrical Nerve Stimulation (TENS) in Women Suffering From Primary Dysmenorrhea.
Status: COMPLETED
Conditions: Dysmenorrhea
Interventions: DEVICE: Livia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Results of the Use of Two Stentrievers Simultaneosly Compared With One as a Primary Treatment in Acute Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke|Thrombectomy|Arterial Occlusive Diseases
Interventions: DEVICE: Double stentriever|DEVICE: Single stentriever
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BEWARE: Body Awareness Training in the trEatment of Wearing-off Related Anxiety in Patients With paRkinson's Disease
Status: UNKNOWN
Conditions: Parkinsonism, Experimental|Parkinsonism, Treatment as Usual
Interventions: BEHAVIORAL: Body awareness therapy|OTHER: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Economic & Staffing Strategies in the ICU
Status: RECRUITING
Conditions: Implementation Science|Delirium|Critical Illness|Mechanical Ventilation Complication|ICU Acquired Weakness|Pain
Interventions: BEHAVIORAL: Realtime audit and feedback|BEHAVIORAL: RN Implementation Facilitator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Misoprostol in Hysteroscopic Myomectomy
Status: NOT_YET_RECRUITING
Conditions: Hysteroscopic Myomectomy
Interventions: DRUG: Misoprostol 400 Microgram Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Trial to Evaluate Efficacy and Safety of rhNGF on Corneal Thickness Via AS-OCT in Neurotrophic Keratitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Neurotrophic Keratitis|Neurotrophic Keratopathy|Corneal Ulcer
Interventions: DRUG: OXERVATE® 0.002%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Everolimus-eluting SYNERGY Stent Versus Biolimus-eluting Biomatrix NeoFlex Stent - SORT-OUT VIII
Status: UNKNOWN
Conditions: Coronary Artery Disease|Ischemic Heart Disease
Interventions: DEVICE: Biomatrix NeoFlex coronary stent|DEVICE: SYNERGY stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of Colchicine With an Oral Contraceptive
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Norethindrone/Ethinyl Estradiol|DRUG: Colchicine|DRUG: Placebo (for Colchicine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long-Term Efficacy and Safety of Intravitreal Aflibercept Injections for the Treatment of Diabetic Retinopathy for Subjects Who Completed the 2-Year PANORAMA Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Retinopathy
Interventions: DRUG: Aflibercept Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Immunogenicity of a H7N9 Vaccine for the Prevention of Influenza H7N9 Disease in Adults 50 to 70 Years Old
Status: COMPLETED
Conditions: Influenza A Virus, H7N9 Subtype
Interventions: BIOLOGICAL: H7N9 Anhui 2013/AA ca|BIOLOGICAL: Inactivated subvirion H7N9 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study on Radiation-induced Pulmonary Fibrosis Treated With Clinical Grade Umbilical Cord Mesenchymal Stem Cells
Status: COMPLETED
Conditions: Post-radiotherapy Pulmonary Fibrosis
Interventions: BIOLOGICAL: clinical grade umbilical cord mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Interest of the Circulating Tumor DNA Dosage in Patient With Hepatic Metastatic Uveal Melanoma Candidate to Complete Resection (ct DNA R0)
Status: COMPLETED
Conditions: Uveal Melanoma
Interventions: BIOLOGICAL: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Stellate Gnaglion Block in Refractory Bell's Palsy
Status: COMPLETED
Conditions: Facial Palsy|Neuropathy
Interventions: PROCEDURE: Stellate Ganglion Block Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Rocatinlimab in Moderate-to-severe Atopic Dermatitis (ROCKET-IGNITE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: Rocatinlimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Stroke Prevention Therapy for Patients With Atrial Fibrillation in Primary Care
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: OTHER: quality improvement toolkit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prevention and/or Reduction of Hemorrhoids and/or Thrombosed External Hemorrhoids Using the HEM-AVERT Perianal Stabilizer Instrument
Status: COMPLETED
Conditions: Hemorrhoids
Interventions: DEVICE: Hem-Avert Perianal Stabilizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study Into Pharmacokinetics and Food Effect of Vapendavir in Healthy Participants and Participants With COPD
Status: COMPLETED
Conditions: COPD|Respiratory Disease|Lower Respiratory Disease|Pulmonary Disease|Healthy
Interventions: DRUG: Vapendavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Embedded Palliative Care in Managing Symptoms in Participants With Recurrent Stage III-IV Thoracic Malignancies and Their Caregivers
Status: COMPLETED
Conditions: Caregiver|Malignant Pleural Neoplasm|Metastatic Thymic Carcinoma|Recurrent Lung Carcinoma|Recurrent Thymic Carcinoma|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: OTHER: Palliative Therapy|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia
Status: RECRUITING
Conditions: B Acute Lymphoblastic Leukemia Associated With Down Syndrome|Down Syndrome|Myeloid Leukemia Associated With Down Syndrome
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Clinical Evaluation|OTHER: Questionnaire Administration|OTHER: Survey Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Malaysia-Singapore Acute Lymphoblastic Leukemia 2010 Study
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia (ALL)
Interventions: DRUG: Prednisolone|DRUG: Dexamethasone|DRUG: L-Asparaginase|DRUG: Vincristine|DRUG: Methotrexate|DRUG: Daunorubicin|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: 6-Mercaptopurine|DRUG: Thioguanine|DRUG: Fludarabine|DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Fish Oils to Reduce the Frequency and Duration of Episodes of Atrial Fibrillation in Patients With Paroxysmal Atrial Fibrillation.
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Fish oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: Varenicline Tartrate Nasal Spray|DRUG: Placebo (vehicle)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency of I-gel Supraglottic Airway Device in Supine and Lateral Decubitus Position in Obese Patient
Status: COMPLETED
Conditions: Obesity, Airway
Interventions: DEVICE: I-gel supraglottic airway device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An "All-Comers" Study of the AgentTM MONORAILTM Paclitaxel-Coated PTCA Balloon Catheter Used in Real-World Clinical Practice in Chinese Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Chinese Patients Treated With Agent DCB
Interventions: DEVICE: AgentTM MONORAILTM Paclitaxel-Coated PTCA Balloon Catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Autologous Transobturator Fascia Lata Sling in Treatment of Female Stress Urinary Incontinence
Status: RECRUITING
Conditions: Stress Urinary Incontinence
Interventions: PROCEDURE: Autologous Transobturator Fascia Lata Sling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Two Carboplatin Containing Regimens for Children and Young Adults With Previously Untreated Low Grade Glioma
Status: UNKNOWN
Conditions: Low Grade Glioma
Interventions: DRUG: Carboplatin|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EF5 in Finding Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Cervical, Endometrial, or Ovarian Epithelial Cancer
Status: COMPLETED
Conditions: Primary Peritoneal Cavity Cancer|Stage I Endometrial Carcinoma|Stage I Ovarian Epithelial Cancer|Stage IA Cervical Cancer|Stage IB Cervical Cancer|Stage II Endometrial Carcinoma|Stage II Ovarian Epithelial Cancer|Stage IIA Cervical Cancer|Stage IIB Cervical Cancer|Stage III Cervical Cancer|Stage III Endometrial Carcinoma|Stage III Ovarian Epithelial Cancer|Stage IV Endometrial Carcinoma|Stage IV Ovarian Epithelial Cancer|Stage IVA Cervical Cancer|Stage IVB Cervical Cancer
Interventions: DRUG: EF5
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Follow-up Study to Evaluate the Efficacy and Safety of Novomax in Posterior Lumbar Interbody Fusion
Status: COMPLETED
Conditions: Degenerative Lumbar Spinal Stenosis
Interventions: DEVICE: Bioactive Glass-Ceramic Spacer|DEVICE: Titanium cage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation (DBS) of the Nucleus Basalis Meynert (NBM) to Treat Cognitive Deficits in Light to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: OTHER: Deep brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Open Label Dose Escalation Study to Evaluate Safety of iHIVARNA-01 in Chronically HIV-infected Patients Under Stable Combined Antiretroviral Therapy
Status: COMPLETED
Conditions: HIV-infection
Interventions: BIOLOGICAL: TriMix_100|BIOLOGICAL: TriMix_300|BIOLOGICAL: 600μg mRNA (300 μg HIV mRNA+300 μg TriMix mRNA)|BIOLOGICAL: 900μg mRNA (600 μg HIV mRNA+300 μg TriMix mRNA)|BIOLOGICAL: 1200μg mRNA (900 μg HIV mRNA+300 μg TriMix mRNA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of a Renal Autologous Cell Therapy (REACT) in Patients With Chronic Kidney Disease (CKD) From Congenital Anomalies of the Kidney and Urinary Tract (CAKUT).
Status: COMPLETED
Conditions: Chronic Kidney Disease|Congenital Anomalies of Kidney and Urinary Tract
Interventions: BIOLOGICAL: Renal Autologous Cell Therapy (REACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Personality Predict Patient Adherence, Health Behaviors, and Weight Loss Outcomes During the Latino Crossover Semaglutide Study (LCSS)? (Story-LCSS Project)
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Body Weight Changes
Interventions: BEHAVIORAL: Voice data
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fecal Microbiota Transplantation for Irritable Bowel Syndrome
Status: RECRUITING
Conditions: Irritable Bowel Syndrome|Fecal Microbiota Transplantation
Interventions: PROCEDURE: fecal microbiota transplantation|PROCEDURE: Infusion of sham|DRUG: probiotics, antibiotics or antidepressants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Rabies Immunoglobulin on Immunogenicity of Post-exposure Rabies Vaccination in Obese Patients
Status: COMPLETED
Conditions: Rabies
Interventions: BIOLOGICAL: Equine Rabies Immunoglobulin|BIOLOGICAL: Purified chick-embryo cell rabies vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Whether the Immediate Use or Deferred Use of an Anti-viral Drug Lamivudine Will Help to Better Safe-guard the Delivery of Chemotherapy in Patients With Cancer Who Are Also Hepatitis B Carriers
Status: COMPLETED
Conditions: Hepatitis B|Neoplasms
Interventions: DRUG: Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tamoxifen or Letrozole in Treating Women With Ductal Carcinoma in Situ
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: letrozole|DRUG: tamoxifen citrate|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIDRAdenitis Suppurativa and HEART Disease
Status: RECRUITING
Conditions: Hidradenitis|Hidradenitis Suppurativa|Hidradenitis Suppurativa, Familial|Left Ventricular Dysfunction|Myocardial Infarction|Myocardial Ischemia|Heart Failure|Stroke|Heart Diseases|Heart Failure, Systolic|Heart Failure, Diastolic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A 17-Week Trial To Assess Pregabalin For The Treatment Of Nerve Pain Due To Spinal Cord Injury
Status: COMPLETED
Conditions: Neuralgia|Spinal Cord Injuries
Interventions: DRUG: placebo|DRUG: pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Significance of Supraclavicular Lymph Node Dissection for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer Stage III
Interventions: PROCEDURE: supraclavicular lymph node dissection|RADIATION: supraclavicular area radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Urinary Urgency Outcomes Following Propiverine Treatment for an Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Propiverine hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Effectiveness of Using Echogenic Embolic Agent for Embolization of Prostate Artery for Treatment of Men With BPH (PAE CEUS)
Status: UNKNOWN
Conditions: Benign Prostatic Hyperplasia
Interventions: PROCEDURE: Embolization of prostatic artery under ultrasound guidance
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Minimally Invasive Versus Open Transforaminal Lumbar Interbody Fusion
Status: UNKNOWN
Conditions: Spinal Fusion
Interventions: PROCEDURE: Transforaminal Lumbar Interbody Fusion either open or minimally invasive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Modified Supine Position on Urinary Elimination After Percutaneous Coronary Intervention
Status: NOT_YET_RECRUITING
Conditions: Urinary Retention
Interventions: OTHER: Modified Supine Position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Serratus Plane Plus Pectoral I Block Versus Serratus Plane Block for Perioperative Analgesia in Breast Cancer Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Postoperative Nausea|Patient Satisfaction|Narcotic Use
Interventions: OTHER: Serratus Plane Block|OTHER: Serratus Plane Block plus Pectoral I Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: TREAT-BE Study (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus)
Status: RECRUITING
Conditions: Barrett's Esophagus|Esophageal Cancer
Interventions: PROCEDURE: Endoscopic eradication therapies (EET)|PROCEDURE: Esophagectomy|DRUG: Chemotherapy|RADIATION: Radiation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low Dose Ketamine (LDK) Versus Morphine for Acute Pain Control in the Emergency Department
Status: COMPLETED
Conditions: Abdomen, Acute|Other Acute Pain|Flank Pain|Back Pain|Musculoskeletal Pain
Interventions: DRUG: Ketamine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT