pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Improving Bystander CPR Quality Through Dispatcher-assisted Basic Life Support Education Program
Status: COMPLETED
Conditions: Out-of-Hospital Cardiac Arrest|Cardiopulmonary Resuscitation
Interventions: OTHER: Dispatcher-Assisted Basic Life Support CPR Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Correlation of Genetic Polymorphism of Azathioprine Metabolizing Enzymes and Correlation to Clinical Adverse Effects
Status: COMPLETED
Conditions: Azathioprine|Thiopurine Methyltransferase|Inosine Triphosphate Pyrophosphatase|Genetic Polymorphism
Interventions: DRUG: Azathioprine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study of Safety and Toxicity of Acquiring Hyperpolarized Carbon-13 Imaging in Children With Brain Tumors
Status: COMPLETED
Conditions: Pediatric Brain Tumors
Interventions: DRUG: Hyperpolarized Pyruvate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Docosahexaenoic Acid (DHA)-Enriched Human Milk in Premature Newborns
Status: TERMINATED
Conditions: Premature
Interventions: DIETARY_SUPPLEMENT: Supplementation of lactating mothers who has delivered prematurely with DHA|DIETARY_SUPPLEMENT: Supplementation of lactating mothers who has delivered prematurely with DHA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET Scans in Assessing Response To Treatment in Patients Receiving Hormone Therapy or Trastuzumab for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: laboratory biomarker analysis|PROCEDURE: needle biopsy|PROCEDURE: positron emission tomography|PROCEDURE: radionuclide imaging|RADIATION: fludeoxyglucose F 18
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Different Anesthetics on Functional Connectivity
Status: RECRUITING
Conditions: Sedation
Interventions: DRUG: Midazolam|DRUG: Propofol|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stress ECG Test for the Evaluation of the Risk of Sudden Cardiac Death in a Paediatric Cohort With WPW Pattern
Status: TERMINATED
Conditions: Wolff-Parkinson-White Syndrome|Sudden Cardiac Death|Risk Stratification
Interventions: DIAGNOSTIC_TEST: Stress test (ECG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safety and Efficacy Evaluation of DOTAREM® in MRI of Central Nervous System (CNS) Lesions
Status: COMPLETED
Conditions: Diagnostic Self Evaluation|Central Nervous System Diseases
Interventions: DRUG: Dotarem (gadoterate meglumine)|DRUG: Magnevist (gadopentetate dimeglumine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Tissue Samples From Patients With Stage I Non-Small Cell Lung Cancer Enrolled on Research Study CALGB-140202
Status: COMPLETED
Conditions: Lung Cancer
Interventions: GENETIC: gene expression analysis|GENETIC: microarray analysis|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Distal Radius Buckle Fracture RCT
Status: COMPLETED
Conditions: Distal Radius Fracture
Interventions: OTHER: Monetary Cost of Immobilization Treatments|OTHER: Physician|OTHER: Study Team|OTHER: Before Initial Treatment Decision|OTHER: After Initial Treatment Decision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study to Compare Bosentan 32 mg Dispersible Tablets Versus Tracleer® 32 mg Tablets
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Bosentan Dispersible Tablets|DRUG: Tracleer Tablet for Oral Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trial To Evaluate The Safety, Tolerability, And Immunogenicity Of A Multivalent Group B Streptococcus Vaccine In Healthy Nonpregnant Women And Pregnant Women And Their Infants
Status: COMPLETED
Conditions: Group B Streptococcus Infections
Interventions: BIOLOGICAL: Multivalent Group B streptococcus vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Placebo-Controlled Trial of Antibiotic Therapy in Adults With Suspect Lower Respiratory Tract Infection (LRTI) and a Procalcitonin Level
Status: TERMINATED
Conditions: Lower Respiratory Tract Infection
Interventions: DRUG: Azithromycin|OTHER: Placebo|DEVICE: VIDAS B.R.A.H.M.S Procalcitonin Test (PCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Amcenestrant (SAR439859) Versus Tamoxifen for Patients With Hormone Receptor-positive (HR+) Early Breast Cancer, Who Have Discontinued Adjuvant Aromatase Inhibitor Therapy Due to Treatment-related Toxicity
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Amcenestrant|DRUG: Tamoxifen|DRUG: Amcenestrant-matching placebo|DRUG: Tamoxifen-matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Combination of Sitagliptin and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia
Status: UNKNOWN
Conditions: Immune Thrombocytopenia|Blood Coagulation Disorders|Thrombocytopenia|Physiological Effects of Drugs
Interventions: DRUG: Sitagliptin|DRUG: Danazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Freeze-dried Live Attenuated Measles/Rubella Combined Vaccine (Schwarz FF-8 Strain/TO-336 Strain) Special Drug Use Surveillance of Vaccinees After the First Vaccination
Status: COMPLETED
Conditions: Measles/Rubella
Interventions: DRUG: Freeze-dried live attenuated measles and rubella combined vaccine (Schwarz FF-8 strain/TO-336 strain)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Safety and Efficacy of Nipent, Cytoxan, and Rituxan
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Cytoxan|DRUG: Nipent|DRUG: Rituxan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy
Status: RECRUITING
Conditions: Pain|Pain Syndrome|Pain, Chronic|Chronic Pain|Chronic Pain Syndrome|Diabetes|Diabetic Neuropathies|Diabetic Polyneuropathy|Peripheral Neuralgia|Peripheral Neuropathy|Peripheral Neuropathy With Type 2 Diabetis
Interventions: DRUG: Adezunap (AP707)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study for the Treatment of Primary Obesity Cross-over Arm
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity, Primary
Interventions: DEVICE: g-Cath EZ Delivery Catheter with Snowshoe Suture Anchors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Epidural Anesthesia and Analgesia on Gut Microbiota
Status: UNKNOWN
Conditions: Living Donor Hepatectomy
Interventions: PROCEDURE: Patient controlled epidural analgesia|DRUG: Intravenous patient controlled analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Stress Assessment With and Without Analgesia During Surfactant Therapy in Preterm Infants.
Status: UNKNOWN
Conditions: Respiratory Distress Syndrome in Premature Infants
Interventions: PROCEDURE: INSURE|PROCEDURE: LISA|DRUG: Analgesic, Opioid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nebulized Hypertonic Saline (3%) Versus Nebulized Adrenaline for Treatment of Bronchiolitis
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: DRUG: Hypertonic saline|DRUG: Adrenaline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Tolerability of PBI-4050 in Type 2 Diabetes Patients With Metabolic Syndrome
Status: COMPLETED
Conditions: Type 2 Diabetes|Metabolic Syndrome
Interventions: DRUG: PBI4050
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Market Study of The Tripod-Fix Vertebral Body Augmentation System in Osteoporotic Vertebral Compression Fractures
Status: RECRUITING
Conditions: Osteoporotic Vertebral Compression Fractures
Interventions: DEVICE: Tripod-Fix Vertebral Body Augmentation System (Tripod-Fix)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Vitamin D Supplementation Prevent Bone Loss in Persons With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Osteoporosis
Interventions: DIETARY_SUPPLEMENT: cholecalciferol|DIETARY_SUPPLEMENT: calcium carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Comparing Tretinoin Cream 0.025% and RETIN-A® Cream 0.025% in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Tretinoin Cream 0.025%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Measuring Oncological Value of Exercise and Statin
Status: RECRUITING
Conditions: Prostate Cancer|Breast Cancer|Kidney Cancer|Ovarian Cancer|Metastatic Breast Cancer|Metastatic Kidney Cancer|Metastatic Renal Cell Carcinoma|Metastatic Renal Cancer|Metastatic Prostate Cancer|Metastatic Prostate Adenocarcinoma|Metastatic Ovarian Cancer|Metastatic Ovary Cancer
Interventions: BEHAVIORAL: Guided physical exercise|DRUG: Atorvastatin|OTHER: Independent exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Meningitis: Burden, Causes, Screening and Prevention in Rural Northern Uganda
Status: RECRUITING
Conditions: Meningitis
Interventions: DIAGNOSTIC_TEST: Pastorex Latex Agglutination Test|DIAGNOSTIC_TEST: Biofire PCR for meningitis|DIAGNOSTIC_TEST: Immy CrAg Lateral Flow Assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Investigating Implant Surface Effect on Osseointegration: NGA vs. ModSLA
Status: NOT_YET_RECRUITING
Conditions: Dental Implant
Interventions: DEVICE: Implant Type
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sciatic Nerve Blockade by Subgluteal Access 12.5 ml of 1% Lidocaine: US Guidance Versus US Guidance With Electrical Stimulation of Peripheral Nerves (Influence of the Sciatic Nerve Blockade on the Effectiveness of Small Doses of Local Anesthetic.).
Status: COMPLETED
Conditions: Nerve Block|Efficiency|Sciatic Nerve|Ultrasonography|Minimum Effective Dose
Interventions: PROCEDURE: Sciatic nerve block under ultrasound control with a electrostimulator peripheral nerves 12.5 ml 1% lidocaine|PROCEDURE: sciatic nerve blockade under ultrasound control without a peripheral nerve stimulator 12.5 ml 1% lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Brivanib Alaninate in Treating Patients With Recurrent or Persistent Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Adenocarcinoma|Endometrial Clear Cell Adenocarcinoma|Endometrial Mixed Adenocarcinoma|Endometrial Mucinous Adenocarcinoma|Endometrial Serous Adenocarcinoma|Endometrial Squamous Cell Carcinoma|Endometrial Transitional Cell Carcinoma|Endometrial Undifferentiated Carcinoma|Recurrent Uterine Corpus Carcinoma
Interventions: DRUG: Brivanib Alaninate|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation on the Risk of Falls and Lower Limb Function for Acute Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Anodal transcranial direct current stimulation|DEVICE: Cathodal transcranial direct current stimulation|DEVICE: Bilateral transcranial direct current stimulation|DEVICE: Sham transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacodynamics of BIIX 1 XX in Healthy Young Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIIX 1 XX - single rising dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Testing a Causal Model of Cognitive Control Deficits in Posttraumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: PTSD
Interventions: PROCEDURE: Transcranial Magnetic Stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Autologous Peripheral Blood Stem Cell Treatment on Articular Cartilage Regeneration
Status: COMPLETED
Conditions: Articular Cartilage Disorder of Knee
Interventions: BIOLOGICAL: Peripheral blood stem cells and hyaluronic acid injections|DRUG: Hyaluronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Obexelimab in Patients With Warm Autoimmune Hemolytic Anemia (SApHiAre)
Status: RECRUITING
Conditions: Warm Autoimmune Hemolytic Anemia
Interventions: DRUG: Obexelimab|DRUG: Obexelimab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Effect of Lactobacillus Reuteri in Treatment of Gingivitis
Status: UNKNOWN
Conditions: Gingivitis
Interventions: DIETARY_SUPPLEMENT: Treatment Gingivitis with Probiotic|OTHER: Treatment Gingivitis conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of a Clinical Assessment and 0h/1h Troponin Rule-Out Protocol
Status: COMPLETED
Conditions: Chest Pain|Acute Coronary Syndrome|Myocardial Infarction|Unstable Angina
Interventions: OTHER: 0h/1h hs-cTnT protocol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reinforcing Effects of Intranasal (IN) Buprenorphine Versus Buprenorphine/Naloxone
Status: COMPLETED
Conditions: Heroin Dependence
Interventions: DRUG: Intranasal challenge drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Helping Stroke Patients With ThermoSuit Cooling
Status: TERMINATED
Conditions: Stroke|Brain Ischemia
Interventions: DEVICE: ThermoSuit Cooling Induction|DRUG: Magnesium Sulfate|DRUG: tPA|DRUG: Propofol|DRUG: Etomidate|PROCEDURE: Neurothrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction and Self Administration Studies of Compounds for Cocaine Use Disorder
Status: COMPLETED
Conditions: Cocaine Use Disorder
Interventions: DRUG: Lorcaserin|DRUG: Cocaine Intravenous (IV)|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: α-synuclein Seeding Activity in the Olfactory Mucosa in COVID-19
Status: UNKNOWN
Conditions: COVID-19
Interventions: OTHER: Real-time Quaking-Induced Conversion (RT-QuIC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Phase III Open-Label Study Of Gabapentin As Adjunctive Therapy In Japanese Pediatric Patients With Partial Seizures
Status: COMPLETED
Conditions: Epilepsies, Partial
Interventions: DRUG: gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dashboards for Clinician Monitoring of Patients Through a Mobile Sensing Platform
Status: COMPLETED
Conditions: Behavioral Health With Medical Comorbidities
Interventions: OTHER: Cogito Companion Intervention|DEVICE: mobile phone application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Randomized Phase II Study of Preoperative Letrozole (Femara) in Combination With Avastin in Hormone Receptor Positive Breast Cancer
Status: TERMINATED
Conditions: Hormone-Sensitive Breast Cancer|Breast Cancer
Interventions: DRUG: Letrozole|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anthropometric And Body Composition Measurements Related To Osteoporosis In Geriatric Population
Status: COMPLETED
Conditions: Osteoporosis Senile|Obesity, Visceral
Interventions: DIAGNOSTIC_TEST: Body mass index|DIAGNOSTIC_TEST: waist circumference|DIAGNOSTIC_TEST: hip circumference|DIAGNOSTIC_TEST: height|DIAGNOSTIC_TEST: Fat percentage|DIAGNOSTIC_TEST: Skeletal muscle index|DIAGNOSTIC_TEST: A body shape index (ABSI)|DIAGNOSTIC_TEST: Dual energy x ray absorptiometry (DXA)|DIAGNOSTIC_TEST: The Rapid Assessment of Physical Activity (RAPA) aerobic assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Flutiform® pMDI in Adult Patients With Mild to Moderate-severe Reversible Asthma
Status: COMPLETED
Conditions: Asthma Bronchiale
Interventions: DRUG: FLUTIFORM® (Formoterol fumarate / Fluticasone propionate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Pattern of Chronic Disease in Adult attendantsabove18years Old in New Vally Elkharga Family Medicine Clinic
Status: NOT_YET_RECRUITING
Conditions: Chronic Wasting Disease of Elk and Deer|Injury; Knee, Meniscus, Old Injury or Tear
Interventions: DIAGNOSTIC_TEST: Urine analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anlotinib Hydrochloride Combined With Capeox in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer
Status: WITHDRAWN
Conditions: Neoadjuvant Treatment|Rectal Cancer|Anlotinib
Interventions: DRUG: Anlotinib+Capeox|DRUG: Capeox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Drug-drug Interaction Study in Healthy Volunteers
Status: COMPLETED
Conditions: Drug-drug Interaction Study
Interventions: DRUG: BMS-986020|DRUG: Montelukast|DRUG: Flurbiprofen|DRUG: Digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Metoprolol on Thalassemia Cardiomyopathy
Status: COMPLETED
Conditions: B Thalassemia
Interventions: DRUG: metoprolol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b/2a Study of the Safety and Pharmacokinetics of Rhu-plasma Gelsolin in Hospitalized Subjects With CAP
Status: COMPLETED
Conditions: Community-acquired Pneumonia
Interventions: DRUG: Recombinant Human Plasma Gelsolin|OTHER: Normal Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of the Effectiveness of Diclofenac Sodium Versus Vitamin D on Myofascial Pain
Status: COMPLETED
Conditions: Myofascial Pain Dysfunction Syndrome,Temporomandibular Joint
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DRUG: Diclofenac Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: No-touch Radiofrequency Ablation for Recurrent Hepatocellular Carcinoma Using Triple Cooled-Wet Electrodes
Status: RECRUITING
Conditions: Recurrent Hepatocellular Cancer|Chronic Liver Disease and Cirrhosis
Interventions: PROCEDURE: Radiofrequency ablation using combined bipolar and monopolar energy deliver with Triple Cooled-Wet electrodes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of P-3073 Nail Solution in the Treatment of Mild to Moderate Psoriatic Fingernail/s
Status: WITHDRAWN
Conditions: Nail Psoriasis
Interventions: DRUG: P-3073 (calcipotriene 0.005%)|DRUG: Vehicle of P-3073
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Selenium Treatment and Chagasic Cardiopathy (STCC)
Status: UNKNOWN
Conditions: Chagas Disease
Interventions: DRUG: Selenium|DRUG: Placebo (for Selenium)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medroxyprogesterone Acetate vs LNG-IUS in Early-stage Endometrioid Carcinoma and Atypical Hyperplasia Patients
Status: RECRUITING
Conditions: Fertility Sparing
Interventions: DRUG: Medroxyprogesterone Acetate 500 MG Oral Tablet|DEVICE: Levonorgestrel-Releasing Intrauterine System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Pharmacokinetics and Safety of 3 Different Formulations of TNX-102 2.8 mg SL Tablets and Cyclobenzaprine 5 mg Oral Tablet in Healthy Adults
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DRUG: TNX-102 SL Tablets at 2.8 mg|DRUG: TNX-102-B SL Tablets at 2.8 mg|DRUG: TNX-102-C SL Tablets at 2.8 mg|DRUG: Cyclobenzaprine tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Dose-escalation Study of Subcutaneous ALM201 in Patients With Advanced Ovarian Cancer and Other Solid Tumours
Status: TERMINATED
Conditions: Solid Tumors|Ovarian Cancer
Interventions: DRUG: ALM201
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study for Efficacy of Cognitive and Physical Training in Patients With Mild Cognitive Impairment
Status: NOT_YET_RECRUITING
Conditions: Patients With Mild Cognitive Impairment (MCI)
Interventions: DEVICE: Using tablets and workbooks cognitive function.|DEVICE: self-programming of physical function training.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neutrophil Gelatinase-associated Lipocalin VS Vascular Calcification in Maintenance Hemodialysis Patients
Status: RECRUITING
Conditions: Chronic Kidney Disease-Mineral and Bone Disorder
Interventions: DRUG: palicalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lung Transplant READY CF 2: CARING CF Ancillary RCT
Status: RECRUITING
Conditions: Cystic Fibrosis
Interventions: BEHAVIORAL: Investigator-designed lung transplant education website
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy Study of Epoetin Alfa in Friedreich Ataxia
Status: COMPLETED
Conditions: Friedreich Ataxia
Interventions: DRUG: Epoetin alfa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation in Disorder of Consciousness in Acute Severe Cerebrovascular Disease Patients
Status: NOT_YET_RECRUITING
Conditions: Ischemic Stroke|Consciousness Disorder|Transcranial Magnetic Stimulation
Interventions: DEVICE: Transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of mRNA-1083 (SARS-CoV-2 and Influenza) Vaccine in Healthy Adult Participants, ≥50 Years of Age
Status: COMPLETED
Conditions: SARS-CoV-2|Influenza
Interventions: BIOLOGICAL: mRNA-1083|BIOLOGICAL: Placebo|BIOLOGICAL: Influenza Vaccine|BIOLOGICAL: COVID-19 Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Efficacy of Fluoride Toothpastes Using an In Situ Caries Model
Status: WITHDRAWN
Conditions: Dental Caries
Interventions: DRUG: Toothpaste containing 1150ppm F|OTHER: Toothpaste containing 0ppm F|DRUG: Toothpaste containing 250ppm F|DRUG: Toothpaste containing 1150ppm F
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy, Safety, and Tolerability Study Comparing Dolutegravir Plus Lamivudine With Dolutegravir Plus Tenofovir/Emtricitabine in Treatment naïve HIV Infected Subjects (Gemini 1)
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus|HIV Infections
Interventions: DRUG: Dolutegravir (DTG)|DRUG: Lamivudine (3TC)|DRUG: Tenofovir disoproxil fumarate/Emtricitabine (TDF/FTC FDC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Vaccine Therapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Recurrent or Refractory Brain Cancer
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: autologous tumor cell vaccine|BIOLOGICAL: filgrastim|BIOLOGICAL: sargramostim|BIOLOGICAL: therapeutic autologous lymphocytes|DRUG: carmustine|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: paclitaxel|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: conventional surgery|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Key Evaluation Techniques and Criteria of Visual Health in Virtual Reality
Status: UNKNOWN
Conditions: Visual Health of Virtual Reality
Interventions: BEHAVIORAL: Watch VR movies/ Play VR games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase 1 Study to Assess the Safety, Tolerability, Pharmacokinetics of DZD8586 in Healthy Adult Participants
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: DZD8586|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing of the Pharmacokinetic, Pharmacodynamic, Safety and Immunogenicity of HS-20090 and Xgeva® in Healthy Adults
Status: UNKNOWN
Conditions: Bone Metastasis From Solid Tumors
Interventions: DRUG: HS-20090|DRUG: Xgeva®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Long-term Treatment of Scalp Psoriasis With Xamiol® Gel in a Large Adult Chinese Population
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Xamiol® gel|DRUG: Daivonex® scalp solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Effect of TMS in Primary Progressive Aphasia
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Progressive Aphasia|Frontotemporal Dementia|Alzheimer Disease
Interventions: DEVICE: Transcranial Magnetic Stimulation (active)|BEHAVIORAL: Language therapy|DEVICE: Transcranial Magnetic Stimulation (sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double Blind, Placebo Controlled, Randomized Phase II Study Evaluating Gemcitabine With or Without Ramucirumab , for II Line Treatment MPM
Status: UNKNOWN
Conditions: Mesothelioma
Interventions: DRUG: Gemcitabine|DRUG: Ramucirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic vs Therapeutic Anticoagulation in Symptomatic Isolated Distal Deep Vein Thrombosis
Status: UNKNOWN
Conditions: Venous Thrombosis
Interventions: DRUG: Rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sub-study of the Essen Study Centre for the ENTAiER Trial
Status: COMPLETED
Conditions: Elderly Patients|Chronically Ill|Increased Risk of Falling
Interventions: OTHER: Eurythmy Therapy|OTHER: Tai Chi|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer mRNA Vaccine (mRNA-1644) and Core-g28v2 60mer mRNA Vaccine (mRNA-1644v2-Core)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hiv
Interventions: BIOLOGICAL: Core-g28v2 60mer mRNA Vaccine|BIOLOGICAL: eOD-GT8 60mer mRNA Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Endoscopic-guided Versus Cotton-tipped Applicator Gauze Pledgetting for Nasal Anesthesia Before Transnasal Endoscopy
Status: UNKNOWN
Conditions: Methods of Nasal Anesthesia Before Transnasal Endoscopy|Side Effects of Transnasal Endoscopy|Patient's Tolerance to Transnasal Endoscopy
Interventions: PROCEDURE: Endoscopic-guided gauze pledgetting|PROCEDURE: Cotton-tipped applicator gauze pledgetting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ablation-Index Guided Scar-Mediated Ventricular Tachycardia Ablation in Patients With Ischemic Cardiomyopathy
Status: NOT_YET_RECRUITING
Conditions: Ventricular Tachycardia|Ischemic Cardiomyopathy
Interventions: PROCEDURE: Ablation-index guided ventricular tachycardia ablation|PROCEDURE: Ventricular tachycardia ablation with no AI-guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 12-Week Study in Adult Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone Propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Amikacin and Cefuroxime in Critically Ill Patients.
Status: UNKNOWN
Conditions: Sepsis|Septic Shock|Infection, Bacterial|Critically Ill
Interventions: DRUG: Cefuroxime|DRUG: Amikacin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multiple-Ascending-Dose Study to Evaluate the Safety of Propoxyphene Napsylate In Healthy Adult Subjects
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Propoxyphene napsylate (XP20C)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Band Ligation Versus Transjugular Intrahepatic Portosystemic Stent Shunt (TIPS) in Cirrhotics With Recurrent Variceal Bleeding Non Responding to Medical Therapy
Status: COMPLETED
Conditions: Gastrointestinal Hemorrhage|Variceal Bleeding|Cirrhosis|Encephalopathy
Interventions: PROCEDURE: endoscopic band ligation|PROCEDURE: TIPS-Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Influence of Socio-aesthetic Care on the Quality of Life of Hemodialysis Patients
Status: RECRUITING
Conditions: Chronic Kidney Insufficiencies
Interventions: OTHER: dialysis and socio-aesthetic care|OTHER: dialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: This is a Study to Determine the Effect of Multiple Doses of an Investigational Drug, Taken by Mouth, in People With Narcolepsy-cataplexy. Accepting Both Males and Females Ages of 18 Years to 55 Years. This Study Will be Conducted in the US and Will Require Approximately 13 Weeks Participation.
Status: COMPLETED
Conditions: Narcolepsy
Interventions: DRUG: SEP363856|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robots Paired With tDCS in Stroke Recovery
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Transcranial Direct Current Stimulation (tDCS)|DEVICE: Placebo sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Equivalence Trial of Percutaneous Lumbar Adhesiolysis and Caudal Epidural Steroid Injections
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: Caudal Epidural Injection|PROCEDURE: percutaneous adhesiolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)
Status: RECRUITING
Conditions: Metastatic Castration-Resistant Prostate Cancer
Interventions: BIOLOGICAL: Pembrolizumab 200 mg|DRUG: Olaparib 400 mg|DRUG: Docetaxel 75 mg/m^2|DRUG: Prednisone 5 mg|DRUG: Enzalutamide 160 mg|OTHER: Dexamethasone 8 mg|DRUG: Olaparib 300 mg|DRUG: Abiraterone acetate 1000 mg|DRUG: Lenvatinib|BIOLOGICAL: Pembrolizumab/Vibostolimab coformulation|DRUG: Carboplatin|DRUG: Etoposide|BIOLOGICAL: Belzutifan 120mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Response Duration and Safety of Xolair (Omalizumab) in Patients With Chronic Idiopathic Urticaria (CIU)/Chronic Spontaneous Urticaria (CSU) Who Remain Symptomatic Despite Antihistamine Treatment (H1)
Status: COMPLETED
Conditions: Chronic Idiopathic Urticaria
Interventions: DRUG: Placebo|DRUG: Omalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CATHETER ANALGESIA TRIAL Phenazopyrdine vs. Placebo: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Catheter-related Bladder Discomfort
Interventions: DRUG: phenazopyridine HCl|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Overall Performance of a 1-day Silicone Hydrogel Lens When Habitual Soft Lens Wearers Are Refit
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: etafilcon A (control)|DEVICE: somofilcon A (test)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Remifentanil on Postoperative Cognition Function in Patients Undergoing Major Abdominal Surgery
Status: COMPLETED
Conditions: Patients Undergoing Major Abdominal Surgery|Postoperative Confusion
Interventions: DRUG: Remifentanil|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: 3D Non-invasive Myocardial Electrical Propagation Mapping as a New Tool to Predict Sudden Death Risk in Patients With Hypertrophic Cardiomyopathy
Status: COMPLETED
Conditions: Hypertrophic Cardiomyopathy
Interventions: DEVICE: CardioInsight™ Noninvasive 3D Mapping System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Higher vs. Lower Doses of Dexamethasone for COVID-19 and Severe Hypoxia
Status: COMPLETED
Conditions: Covid19|Hypoxia
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Robot-Assisted Simple Enucleation Versus Standard Robot-Assisted Partial Nephrectomy in the Treatment of T1 Renal Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: PROCEDURE: endoscopic robot-assisted simple enucleation|PROCEDURE: standard robot-assisted partial nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standardized Protocol of Surgery and Radiation for Patients With Brain Metastases in Relapsed Neuroblastoma
Status: WITHDRAWN
Conditions: Relapsed Neuroblastoma
Interventions: RADIATION: Cerebral Spinal (CS) radiation|RADIATION: Focal radiotherapy (SRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Cabergoline Tablets and Dostinex Under Fed Conditions
Status: COMPLETED
Conditions: To Determine Bioequivalence Under Fed Conditions
Interventions: DRUG: Cabergoline|DRUG: Dostinex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Anemia Correction and Fibroblast Growth Factor 23 Levels in Chronic Kidney Disease , and Renal Transplant Patient
Status: SUSPENDED
Conditions: Anemia of Chronic Kidney Disease|Endothelial Dysfunction|Left Ventricular Hypertrophy|Fibroblast Growth Factor 23
Interventions: DIAGNOSTIC_TEST: detailed echocardiography|DIAGNOSTIC_TEST: serum fibroblast growth factor-23|DIAGNOSTIC_TEST: flow mediated dilatation of forearm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Assess the Ability of the Portable Scalp Cooling System (PSCS) to Prevent Hair Loss
Status: NOT_YET_RECRUITING
Conditions: Alopecia|Chemotherapy-induced Alopecia|Hair Loss|Breast Cancer
Interventions: DEVICE: AMMA Portalbe Scalp Cooling System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of a Self-guided Mobile Phone Application in Improving the Way we See Ourselves and Our Bodies
Status: COMPLETED
Conditions: Body Image
Interventions: BEHAVIORAL: Self-guided programme on body image|BEHAVIORAL: Self-guided programme on cooperation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Trial of a Social Skills Group Treatment (Secret Agent Society Program)
Status: COMPLETED
Conditions: Anxiety|Attention Deficit Hyperactivity Disorder (ADHD)|Autistic Spectrum Disorder (ASD)
Interventions: BEHAVIORAL: Secret Agent Society (SAS) Program|OTHER: Waitlist Group / Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Techniques in Achieving Corneal Graft
Status: COMPLETED
Conditions: Fuch's Endothelial Dystrophy
Interventions: PROCEDURE: Endothelial descemet membrane graft|PROCEDURE: Endothelial descemet membrane graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Treatment Planning Utilizing 18-FDGal PET/CT in SBRT for Liver Metastases
Status: UNKNOWN
Conditions: Liver Metastases
Interventions: OTHER: measuring liver function by 18-FDGal PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dosing Requirements of Astagraf XL® in African American Kidney Transplant Recipients
Status: COMPLETED
Conditions: Immunosuppression
Interventions: DRUG: Tacrolimus Extended Release Capsule|DRUG: Mycophenolate mofetil|DRUG: Prednisone|DRUG: Mycophenolate Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Study of Active Specific Immunotherapy With OncoVax® in Patients With Stage II Colon Cancer
Status: UNKNOWN
Conditions: Stage II Colon Cancer
Interventions: BIOLOGICAL: OncoVAX and Surgery|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interventional Study of Mucosal and Antimicrobial Responses to Repeated Vaginal Applications of Tenofovir Gel in HIV Uninfected Women
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Tenofovir gel|DRUG: Tenofovir gel placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Integrated Experiential Training Program With Coaching by Nursing Students in Childhood Cancer Patients
Status: COMPLETED
Conditions: Child|Neoplasms
Interventions: BEHAVIORAL: an integrated experiential training program with coaching|BEHAVIORAL: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: NutriMind: A Combination of Healthy Diet and Psychotherapy to Treat Depression
Status: RECRUITING
Conditions: Depression
Interventions: OTHER: Healthy Diet|BEHAVIORAL: Mindfulness-based cognitive therapy (MBCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health Status of < 50 Year Old Patients After Surgically Implanted Biological and Mechanical Aortic Valves: a Population-based Retrospective Analysis (2010-2020)
Status: COMPLETED
Conditions: Aortic Valve Disease
Interventions: DEVICE: Aortic Valve Replacement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison Between Conventional Angiocatheter Versus New Anchoring Device (KARAHOC) Used for Paracentesis
Status: ENROLLING_BY_INVITATION
Conditions: Ascites Hepatic
Interventions: DEVICE: KARAHOC device|DEVICE: Angiocatheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Life and Pain Changes Due to DRG Stimulation for Chronic Pain
Status: TERMINATED
Conditions: Spinal; Nerve Root, Pain|Pelvic Pain|Regional Pain Syndrome|Chronic Pain Syndrome|Complex Regional Pain Syndromes
Interventions: DEVICE: dorsal root ganglion neuromodulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Mannitol on Delayed Graft Function After Cadaveric Renal Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation, Mannitol
Interventions: DRUG: Mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT