pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Donor Stem Cell Transplantation for Congenital Immunodeficiencies
Status: COMPLETED
Conditions: Inherited Immune Deficiencies
Interventions: DRUG: Campath 1H|DRUG: Busulfan|DRUG: Horse Anti-human Thymocyte Globulin (h-ATG)|DRUG: Total Body Irradiation (TBI)|DRUG: Sirolimus or equivalent based on response
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Changes in Blood Samples From Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Recurrent Adult Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: OTHER: Cytology Specimen Collection Procedure|OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Investigate Safety, Tolerability, Pharmacokinetics & Pharmacodynamics of Single & Repeat Doses of GSK2269557
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: GSK2269557|DRUG: GSK2269557 matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phytoserms for Menopause Symptoms and Age-Associated Memory Decline
Status: COMPLETED
Conditions: Hot Flashes|Memory Loss
Interventions: DIETARY_SUPPLEMENT: PhytoSERM tablet|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effects of Multiple Dose Fluoxetine and Metabolites on CYP1A2, CYP2C19, CYP2D6 and CYP3A4 Activity
Status: COMPLETED
Conditions: Drug-Drug Interaction|Healthy Volunteers
Interventions: DRUG: Fluoxetine, Lovastatin, Omeprazole, caffeine, midazolam, dextromethorphan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Dronedarone on Atrial Fibrillation Burden in Subjects With Permanent Pacemakers
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: DRUG: Dronedarone|DRUG: Placebo (for Dronedarone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of tDCS Based on Functional Brain Imaging for Subacute Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Transcranial Direct Current Stimulation|BEHAVIORAL: Hand motor task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STALL vs Sole Local Wound Infiltration in Laparoscopic Cholecystectomy
Status: RECRUITING
Conditions: Cholelithiasis|Cholecystitis|Gallbladder Cancer
Interventions: PROCEDURE: single transversus abdominis laparoscopy-guided plane block|PROCEDURE: local trocar site ropivacaine infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Evaluating the Safety and Efficacy of Tirofiban in Combination With Alteplase in Acute Ischemic Stroke
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Tirofiban 0.05 MG/ML|DRUG: 0.9% sodium chloride solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 4 Gastrointestinal Tolerability Study of Dimethyl Fumarate in Patients With Relapsing Forms of Multiple Sclerosis in the United States
Status: COMPLETED
Conditions: Relapsing Forms of Multiple Sclerosis
Interventions: DRUG: BG00012 (DMF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lingual Keratinized Tissue in Fully Edentulous Patients and Its Impact on Implant Health
Status: NOT_YET_RECRUITING
Conditions: Peri-Implantitis|Peri-implant Mucositis|Recession, Gingival
Interventions: OTHER: Exposure to minimal amount of lingual keratinized tissue width
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Application of Artificial Intelligence in Early Detection of Eye Complications in Diabetics
Status: NOT_YET_RECRUITING
Conditions: Artificial Intelegence|Diabetic Retinopathy Associated With Type 2 Diabetes Mellitus|Macular Edema Due to Type 2 Diabetes Mellitus
Interventions: OTHER: AI based eye screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: mFOLXOX6 Versus FOLFIRI for Colorectal Patients Recurrence After Oxaplatin Based Adjuvant Chemotherapy
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CANabidiol Use for RElief of Short Term Insomnia
Status: COMPLETED
Conditions: Sleep Disturbance|Insomnia|Insomnia Type; Sleep Disorder|Insomnia, Transient|Insomnia Due to Anxiety and Fear|Insomnia Due to Other Mental Disorder
Interventions: DRUG: 50 mg Cannabidiol (CBD)|DRUG: Placebo|DRUG: 100 mg Cannabidiol (CBD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Ociperlimab Plus Tislelizumab Versus Durvalumab Following Concurrent Chemoradiotherapy (cCRT) in Patients With Stage III Unresectable Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Tislelizumab|DRUG: Durvalumab|DRUG: Ociperlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of Tacrolimus-based Immunosuppression on Heidelberg Liver Transplant Cohort (HDTACRO): Study Protocol for an Investigator Initiated, Non-interventional Prospective Study
Status: UNKNOWN
Conditions: Liver Transplantation
Interventions: DRUG: Tacrolimus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Kinesio Taping and Dry Needling in Grade 1, 2 Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Kinesio Taping|OTHER: Dry Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical and Oncologic Outcomes After Robotic Nipple Sparing Mastectomy and Immediate Reconstruction
Status: COMPLETED
Conditions: Postoperative Complications|Recurrence|Breast Neoplasms|Breast Cancer|BRCA1 Mutation|BRCA2 Mutation|Surgery|Surgery--Complications
Interventions: PROCEDURE: Robotic nipple sparing mastectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate Efficacy and Safety of JTZ-951 Compared to Darbepoetin Alfa in Korean Renal Anemia Patients Receiving Hemodialysis.
Status: COMPLETED
Conditions: Anemia of Chronic Kidney Disease
Interventions: DRUG: JTZ-951|DRUG: Darbepoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continual vs. Routine Home Blood Pressure Monitoring and Management in Diverse Community Practice: CHANGE-BP
Status: NOT_YET_RECRUITING
Conditions: Hypertension
Interventions: DEVICE: Aktiia Device|DEVICE: Upper arm cuff
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Cordyceps Sinensis Mycelium Culture Extract(Paecilomyces Hepiali, CBG-CS-2) on Promotion of Immunity
Status: COMPLETED
Conditions: Immunity
Interventions: DIETARY_SUPPLEMENT: Cordyceps sinensis mycelium culture extract 1.68 g|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PET Imaging of 68Ga-Her2-affibody in Tumors With High Her2 Expression
Status: NOT_YET_RECRUITING
Conditions: Neoplasms
Interventions: DRUG: 68Ga-Her2-affibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cardiac Arrest Bundle of cARE Trial
Status: NOT_YET_RECRUITING
Conditions: Cardiopulmonary Resuscitation|Cardiac Arrest|Out of Hospital Cardiac Arrest
Interventions: PROCEDURE: Neuroprotective 'bundle of care'
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Automatic Surveillance System on Surveillance Rate of Patients With Gastric Premalignant Lesions
Status: NOT_YET_RECRUITING
Conditions: Artificial Intelligence|Surveillance
Interventions: OTHER: AI based automatic surveillance (AS) system (ENDOANGEL-AS)|OTHER: Manually remind the patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: Incidence of Postoperative Delirium in Cancer Patients After Laparoscopic Surgery in Trendelenburg Position
Status: COMPLETED
Conditions: Delirium|Anesthesia
Interventions: PROCEDURE: Subarachnoid block|PROCEDURE: Spinal morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Infusion Flow Rates and Blood Sampling
Status: UNKNOWN
Conditions: Intraosseous Access|Infusion Rates|Intraosseous Blood|Venous Blood
Interventions: DEVICE: Intraosseous access
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Anlotinib Plus Etoposide and Carboplatin as First-line Treatment for Extensive-stage Small Cell Lung Cancer
Status: UNKNOWN
Conditions: SCLC|Anlotinib
Interventions: DRUG: Anlotinib hydrochloride|DRUG: Etoposide|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outpatient Hematopoietic Grafting in Multiple Sclerosis Employing Autologous Peripheral Blood Stem Cells
Status: ENROLLING_BY_INVITATION
Conditions: Multiple Sclerosis
Interventions: PROCEDURE: Hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Based Couples Therapy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Mindfulness-Based Relationship Enhancement (MBRE)|BEHAVIORAL: Self-Help Materials|BEHAVIORAL: Pain Assessment|BEHAVIORAL: Questionnaires|BEHAVIORAL: Neurocognitive Tests|PROCEDURE: Cortisol Tests|BEHAVIORAL: Interviews
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Postoperative Recovery of Sevoflurane and Propofol After Transsphenoidal Surgery
Status: RECRUITING
Conditions: Pituitary Adenoma
Interventions: DRUG: sevoflurane|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MR Guided Focused Ultrasound Surgery in the Treatment of Uterine Fibroids: Software V4.2 Validation
Status: COMPLETED
Conditions: Uterine Fibroids|Uterine Leiomyomas
Interventions: DEVICE: ExAblate 2000
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of TQ-B3139 Versus Crizotinib in the First Line Treatment of Subjects With Anaplastic Lymphoma Kinase (ALK) Positive Non-Small Cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: ALK-positive NSCLC
Interventions: DRUG: TQ-B3139|DRUG: Crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flavonoids in the Treatment of Endothelial Dysfunction in Children With Diabetes
Status: WITHDRAWN
Conditions: Diabetic Nephropathy|Endothelial Dysfunction
Interventions: DIETARY_SUPPLEMENT: flavonoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Contralateral Dispensing Clinical Trial of Study Test Silicone Hydrogel Lens Against Enfilcon A Silicone Hydrogel Lens
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Sapphire Lens|DEVICE: enfilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nutrition Intervention to Decrease Symptoms in Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: BEHAVIORAL: Sodium reduction|DIETARY_SUPPLEMENT: omega 3 and lycopene supplements|DIETARY_SUPPLEMENT: rice bran oil capsules|BEHAVIORAL: Generic dietary feedback from
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Follow Up Safety Study of SCH 420814 in Subjects With Parkinson's Disease (P05175)
Status: COMPLETED
Conditions: Parkinson Disease|Neurodegenerative Diseases|Central Nervous System Diseases|Movement Disorders|Brain Diseases
Interventions: DRUG: Preladenant|DRUG: L-dopa|DRUG: Other Parkinson's Disease treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral β-Alanine Supplementation in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DIETARY_SUPPLEMENT: beta-alanine|DIETARY_SUPPLEMENT: placebo|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia
Status: COMPLETED
Conditions: Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)
Interventions: DRUG: Epanova® (omega-3 carboxylic acids)|DRUG: corn oil control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hub and Spoke, Comparative Outcomes for Parkinson's Disease Treated With Deep Brain Stimulation
Status: WITHDRAWN
Conditions: Parkinson's Disease
Interventions: PROCEDURE: Programming by community Neurologist|PROCEDURE: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Immunization With an Attenuated Listeria Monocytogenes Vector Vaccine
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: BMB72 (actA/plcB-deleted Listeria monocytogenes expressing influenza A nucleoprotein)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Mometasone Furoate DPI Versus Budesonide DPI in Budesonide DPI in Asthmatics (Study P04880)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: mometasone furoate dry powder inhaler|DRUG: Budesonide DPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RSA Study on the Behaviour of the Growth Plate During and After Temporary Hemi-epiphysiodesis and Epiphysiodesis
Status: RECRUITING
Conditions: Anisomelia|Deformity of Limb
Interventions: OTHER: Temporary hemi-epiphysiodesis or epiphysiodesis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Potential Effect of Avena Sativa L. on Wellness/Wellbeing During Smoking Reduction/Cessation Experience
Status: COMPLETED
Conditions: Smoking Reduction
Interventions: DIETARY_SUPPLEMENT: Experimental product consumption|OTHER: Control product consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Osimertinib and Gefitinib in EGFR Inhibitor naïve Advanced EGFR Mutant Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Gefitinib|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Dose of Prophylactic Dexamethasone for Elderly Patients Receiving Moderate Emetogenic Chemotherapy
Status: COMPLETED
Conditions: Colonic Neoplasms
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Strategic Treatment Reduction in Very Early Liver Disease With 4 Weeks Sofosbuvir Plus Glecepravir-pibrentasvir
Status: RECRUITING
Conditions: Hepatitis C
Interventions: DRUG: Sofosbuvir 400mg [Sovaldi]|DRUG: Glecaprevir/pibrentasvir (300mg/120mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of MEDI-522 On Disease Activity and Progression of Joint Damage in Patients With Active Rheumatoid Arthritis Suboptimally Responding to Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: MEDI-522|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Evaluate the Safety, Tolerability, PK/PD of SRSD107 in Healthy Participants
Status: RECRUITING
Conditions: Thrombosis
Interventions: DRUG: SRSD107|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TO ASSESS THE EFFICACY AND SAFETY OF PF-06650833, PF-06651600, AND TOFACITINIB ALONE AND IN COMBINATION IN PARTICIPANTS WITH ACTIVE RHEUMATOID ARTHRITIS WITH AN INADEQUATE RESPONSE TO METHOTREXATE
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: PF-06650833|DRUG: PF-06651600|DRUG: Tofacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conservative Therapies in the Treatment of Temporomandibular Disorders
Status: RECRUITING
Conditions: Temporomandibular Joint Disorders|Temporomandibular Joint Pain|Splints|Photobiomodulation
Interventions: DEVICE: Occlusal Splint|RADIATION: Laser Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Large-scale Brain Organization During Cognitive Control in ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Methylphenidate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Donepezil on Gait and Balance in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Donepezil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Comprehensive Migraine Intervention
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Naproxen|DRUG: Sumatriptan|BEHAVIORAL: Migraine education|BEHAVIORAL: Reenforcement of diagnosis|OTHER: Typical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Rapid Assessment of Cardiac Markers for the Evaluation of Acute Coronary Syndrome (RACE-ACS)
Status: WITHDRAWN
Conditions: Acute Coronary Syndrome
Interventions: DEVICE: Triage CardioProfilER (Troponin I, Myoglobin, CK-MB, BNP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prevention of Low Blood Pressure After Cardiac Surgery in Heart Failure Patients With a Filter Called CytoSorb.
Status: RECRUITING
Conditions: Heart Failure|Vasoplegia
Interventions: DEVICE: CytoSorb device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Glargine Versus NPH in Patients With Chronic Kidney Disease
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Chronic Kidney Disease
Interventions: DRUG: Glargine insulin|DRUG: NPH insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Avoidance Behavior and Its Relation to Risk for Opioid Use in Chronic Pain Patients
Status: RECRUITING
Conditions: Chronic Pain|Opioid Use
Interventions: DIAGNOSTIC_TEST: Electroencephalography (EEG)/Magnetoencephalography (MEG)/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Deficits, Adaptation and Cerebral Functional Reorganization of Visual Retinotopic Treatments During Normal and Pathological Aging (Age-related Macular Degeneration and Glaucoma)
Status: TERMINATED
Conditions: Macular Degeneration|Glaucoma
Interventions: RADIATION: Functional Magnetic Resonance Imaging (fMRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Evorpacept (ALX148) With Azacitidine for Higher Risk Myelodysplastic Syndrome (ASPEN-02)
Status: ACTIVE_NOT_RECRUITING
Conditions: Higher Risk Myelodysplastic Syndromes
Interventions: DRUG: evorpacept|DRUG: azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genotype-Directed Study Of Irinotecan Dosing In FOLFIRI + BevacizumabTreated Metastatic Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colon Cancer
Interventions: DRUG: 5-Fluorouracil|DRUG: Leucovorin|DRUG: Irinotecan|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Absorption of Dietary Phosphorus When Administering FOSRENOL® or RENVELA® in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Kidney Failure, Chronic
Interventions: DRUG: Lanthanum Carbonate|DRUG: Sevelamer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Electroacupuncture Therapy for Change of Pain in Classical Trigeminal Neuralgia
Status: COMPLETED
Conditions: Trigeminal Neuralgia
Interventions: OTHER: EA+ Carbamazepine|OTHER: EA+Placebo|OTHER: sham EA+Carbamazepine|OTHER: sham EA+Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Novartis Meningococcal ACWY Conjugate Vaccine in Healthy Children Aged 12-59 Months.
Status: COMPLETED
Conditions: Meningococcal Meningitis
Interventions: BIOLOGICAL: MenACWY-CRM conjugate vaccine, adjuvanted|BIOLOGICAL: MenACWY polysaccharide vaccine|BIOLOGICAL: MenACWY-CRM conjugate vaccine, unadjuvanted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Lung Volume Recruitment Combined With Expiratory Muscle Strength Training in ALS
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: PROCEDURE: Expiratory Muscle Strength Training (EMST)|PROCEDURE: EMST + Lung Volume Recruitment (LVR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Motor Imagery Training on Gait and Balance in Children With Spastic Hemiplegia
Status: UNKNOWN
Conditions: Cerebral Palsy, Spastic
Interventions: OTHER: Selected physical Therapy program|OTHER: Motor imagery training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 4-Week Study of Efficacy, Safety and PK of Albuterol-HFA Versus Proventil-HFA in Pediatric Asthma
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: Armstrong Albuterol Sulfate Inhalation Aerosol|DRUG: Albuterol Sulfate Inhalation Aerosol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Thymoglobin in Renal Transplant Patients
Status: COMPLETED
Conditions: Acute Renal Failure
Interventions: DRUG: Thymoglobulin|DRUG: Thymoglobulin 0.75mg/kg dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Echo-guided Transverse Abdominal Plane Block (TAP) in Anterior Lumbar Arthrodesis (ALIF)
Status: RECRUITING
Conditions: Fusion of Spine, Lumbar Region
Interventions: DRUG: Levobupivacaine|OTHER: Placebo Tap block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Therapy With Bevacizumab (BEV), Doxorubicin, and Cyclophosphamide Followed by BEV, Docetaxel, and Capecitabine Before Surgery Followed by BEV Alone After Surgery for Women With Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Bevacizumab|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Capecitabine|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computerized Cardiotocography Monitoring of Fetuses With pPROM
Status: UNKNOWN
Conditions: Cardiotocography|Premature Rupture of Membrane|Rupture of Membranes; Premature|Sepsis|Premature Birth
Interventions: DIAGNOSTIC_TEST: Computerized cardiotocography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of Pectoralis Muscle Strength in Elderly With Interstitial Lung Disease
Status: COMPLETED
Conditions: Interstitial Lung Disease|Idiopathic Pulmonary Fibrosis|Sarcoidosis, Pulmonary|Geriatric
Interventions: OTHER: Assessment of pulmonary function and pectoralis muscle strength
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Temperature by Infrared Thermography and Blood Conduction Velocity by Doppler After Applying Shortwave Diathermy and Microwave - Correlations With Cardiovascular and Hemodynamic Parameters
Status: COMPLETED
Conditions: Healthy Individuals
Interventions: OTHER: Shortwave therapy|OTHER: Microwave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase IB Study to Evaluate RAD1901 on the Availability of Estrogen Receptor Binding Sites in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: RAD1901
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Roy Adaptation Model Based Strengthening Program and Social Media Addiction
Status: COMPLETED
Conditions: Social Media Addiction
Interventions: OTHER: Roy Adaptation Model Based Strengthening Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Lacosamide on Human Motor Cortex Excitability: a Transcranial Magnetic Stimulation Study
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: Lacosamide|DRUG: Placebo|DRUG: Carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of an Hypnotherapy Session on the NOL Variations After Stimulation
Status: COMPLETED
Conditions: Anesthesia|Hypnosis|Pain
Interventions: OTHER: Medical hypnosis session|OTHER: control groupe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Rosuvastatin in Healthy Volunteers Under Fasting Condition
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Rosuvastatin 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Single Ascending Dose Challenge Study to Determine Safety and Reactogenicity of an Influenza Challenge Virus
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Live, wild-type A/California/H1N1 2009 influenza virus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Psychological and Physical Effects of an 8-Week Electromyostimulation-Workout
Status: UNKNOWN
Conditions: Healthy
Interventions: DEVICE: Electromyostimulation Whole-Body-Workout|DEVICE: Electromyostimulation Sham Whole-Body-Workout
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain, Range of Motion, Edema, Sensibility, Strength (PRESS) & Self-reported Function Create a Comprehensive Score
Status: COMPLETED
Conditions: Hand Injuries and Disorders|Upper Extremity Problem
Interventions: OTHER: Upper Extremity Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pharmacokinetics, Safety, and Preliminary Efficacy of Isatuximab in Chinese Patients With Relapsed and/or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Isatuximab SAR650984
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cell-free Autologous Regenerative Endodontics Treatment for Teeth With Periapical Lesions (CARETT)
Status: NOT_YET_RECRUITING
Conditions: Periapical Diseases|Pulp Necroses
Interventions: PROCEDURE: Autologous Regenerative Endodontic Treatment|PROCEDURE: Conventional Root Canal Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Rehabilitation Training on Orthostatic Hypotension in Parkinson's Patients
Status: RECRUITING
Conditions: Orthostatic Hypotension
Interventions: BEHAVIORAL: Comprehensive rehabilitation training|BEHAVIORAL: Rise-bed Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hemodynamic Stability of Dexmedetomidine in Hypertensive Patients Undergoing Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Hypertension|Laparoscopic Cholecystectomy
Interventions: DRUG: Dexmedetomidine injection|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Relative Bioavailability Study of Revatio for the Crushed Tablets, Extemporaneously Prepared Formulation, and the Intact Tablets at 20 mg Dose in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Revatio|DRUG: Revatio|DRUG: Revatio
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison Between Different Horizontal Ridge Augmentation Techniques
Status: COMPLETED
Conditions: Atrophic Ridge
Interventions: PROCEDURE: horizontal ridge augmentation by decompression technique.|PROCEDURE: horizontal ridge augmentation by ridge splitting technique using piezosurgery.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Segmented Versus Full Arch Three Dimensionally Printed Transfer Tray for Orthodontic Indirect Bonding
Status: UNKNOWN
Conditions: Inaccurate Transfer and Bond Failure of Conventional Indirect Bonding Tray|Accuracy of Bracket Transfer and Bond Failure Rate of Full Arch and Segmented Digitally Printed Trays
Interventions: OTHER: Segmented three dimensionally printed transfer tray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Bioavailability of Tiotropium + Olodaterol Fixed-dose Combination (5 μg/ 5 μg) in Chinese COPD Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium|DRUG: Olodaterol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mild Hypothermia in Cardiogenic Shock Complicating Myocardial Infarction
Status: COMPLETED
Conditions: Acute; Myocardial Infarction, Complications|Cardiogenic Shock
Interventions: PROCEDURE: Mild hypothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Role of Ghrelin in Regulating Appetite and Energy Intake in Patients Following Bariatric Surgery (BARI-INSIGHT)
Status: COMPLETED
Conditions: Obesity|Bariatric Surgery Candidate|Appetitive Behavior
Interventions: DRUG: GLWL-01|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Postpartum Breastfeeding Education on Breastfeeding Self-efficacy and Breastfeeding Success
Status: COMPLETED
Conditions: Breastfeeding
Interventions: OTHER: breastfeeding education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Local Administration of Tranexamic Acid in Upper Gastrointestinal Hemorrhage
Status: COMPLETED
Conditions: Gastrointestinal Hemorrhage|Tranexamic Acid|Emergency Department|Antifibrinolytic Agents
Interventions: DRUG: Tranexamic acid 5%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Influence of Vitamin D on Vascular Function in Adolescents and Young Adults With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Escalating Single and Multiple Doses of KP104
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: KP104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intranasal Insulin and Glutathione as an Add-On Therapy in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DRUG: INS-GSH|DRUG: Matched Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Washed Microbiota Transplantation for Diabetic Gastroparesis
Status: RECRUITING
Conditions: Diabetic Gastroparesis
Interventions: OTHER: washed microbiota transplantation|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bupivacaine Versus Liposomal Bupivacaine For Breast Pain Management After Breast Recontruction
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: Liposomal Bupivacaine|DRUG: Bupivacaine|DRUG: Patient-Controlled Analgesia Pump|DRUG: Oral Narcotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving Dental Health Among Toddlers in the Dominican Republic
Status: COMPLETED
Conditions: Dental Caries in Children|Dental Caries
Interventions: BEHAVIORAL: Oral Health education including printed educational material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pleural Irrigation With Normal Saline Versus Intrapleural Fibrinolytic
Status: RECRUITING
Conditions: Pleural Infection
Interventions: DRUG: Intrapleural fibrinolytic with alteplase 5mg and pulmozyme 5 mg|OTHER: Saline irrigation with 250 mls normal saline (over 1 hour)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GI Alpha-Gal Study
Status: RECRUITING
Conditions: Alpha-Gal Syndrome|Irritable Bowel Syndrome|Diarrhea|Abdominal Pain|Vomiting
Interventions: OTHER: Ground pork containing alpha-gal|OTHER: Pork meat not containing alpha-gal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Test the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
Status: ENROLLING_BY_INVITATION
Conditions: Stereotypical Prolonged Seizures
Interventions: DRUG: Staccato alprazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Preoperative Prone Position Training on PPCs in Patients Undergoing Laparoscopic Sleeve Gastrectomy
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pulmonary Complications
Interventions: BEHAVIORAL: Prone Position Training|BEHAVIORAL: standard perioperative care without any prone position training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Medico-economic Study of the Subglottic Secretions Drainage in Prevention of Ventilator-associated Pneumonia (DEMETER)
Status: COMPLETED
Conditions: Ventilator-associated Pneumonia
Interventions: DEVICE: Endotracheal tubes not allowing SSD|DEVICE: Endotracheal tubes allowing SSD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Cervical Screening in Unvaccinated, Herd Effect Protected Women (HPV400)
Status: ENROLLING_BY_INVITATION
Conditions: Cervical Intraepithelial Neoplasia Grade 2/3|Adenocarcinoma in Situ
Interventions: OTHER: Frequent information of cytological/ HPV DNA screening results
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Study of 2LPAPI® on the Clearance of Genital HR-HPV Infections.
Status: RECRUITING
Conditions: Human Papilloma Virus
Interventions: DRUG: 2LPAPI®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Comparison Of Intravenous Ibuprofen And Intravenous Paracetamol In Management Of Pediatric Fever
Status: COMPLETED
Conditions: Fever
Interventions: DRUG: Intravenous Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Long-term Safety of Etrolizumab in Participants With Moderate to Severe Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Etrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess Efficacy and Safety of a Nasal Spray in Adults With Dry or Irritated Nose
Status: RECRUITING
Conditions: Dry Nose
Interventions: DEVICE: Sterimar Stop & Protect Irritation & Dryness
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intravenous Immunoglobulin in Management of Rh and ABO Incompatibility Disease
Status: UNKNOWN
Conditions: Haemolysis Neonatal
Interventions: DRUG: intravenous immunoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Energy Drink Consumption on Alcohol-Substance Use and It's Relationship With Impulsivity In University Students
Status: COMPLETED
Conditions: Energy Drinks|Alcohol Drinking|Substance Use|University Students
Interventions: OTHER: Addiction Profile Index|OTHER: Alcohol Use Disorders Identification Test|OTHER: Barratt Impulsiveness Scale|OTHER: Zuckerman Sensation Seeking Scale|OTHER: Energy Drink Consumption Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Pharmacokinetics/Pharmacodynamics of Oral Salmon Calcitonin in Patients With Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Oral salmon calcitonin, salmon calcitonin nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Siltuximab Plus Best Supportive Care to Placebo Plus Best Supportive Care in Anemic Patients With International Prognostic Scoring System Low- or Intermediate-1-Risk Myelodysplastic Syndrome
Status: TERMINATED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: Siltuximab|DRUG: Placebo|DRUG: Best supportive care (BSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SEdation Versus General Anesthesia for Endovascular Therapy in Acute Ischemic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Sedation|DRUG: General Anesthesia (GA)|PROCEDURE: Intra-arterial Thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Microflora Characteristics of Pancreatic Solid Lesions Via Endoscopic Ultrasound-guided Fine Needle Aspiration/Biopsy
Status: COMPLETED
Conditions: Pancreatic Carcinoma|Pancreatic Neuroendocrine Tumor|Autoimmune Pancreatitis|Microflora
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Controlled Trail Comparing Subthalamic and Pallidal Deep Brain Stimulation for Dystonia
Status: COMPLETED
Conditions: Dystonia
Interventions: DEVICE: Deep Brain Stimulation (DBS) of Gpi|DEVICE: Deep Brain Stimulation (DBS) of STN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atrificial Shrinkage of Blastocyst Before In Vitro Fertilization
Status: COMPLETED
Conditions: Infertility
Interventions: DEVICE: ICSI with laser pulse|DEVICE: ICSI with micro needle technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Endovascular Treatment of Thoracic Aortic Disease
Status: ENROLLING_BY_INVITATION
Conditions: Thoracic Aortic Aneurysms|Dissecting, Aneurysm|Ascending Aorta Aneurysm|Aortic Arch; Aneurysm, Dissecting|Ascending Aortic Dissection|Thoracoabdominal Aortic Aneurysm|Renal Artery Aneurysm|Superior Mesenteric Artery Aneurysm|Aortic Dissection
Interventions: DEVICE: Endovascular stent-graft implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wrist Extensor MEP Up-conditioning for Individuals With Incomplete Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries|Quadriplegia
Interventions: BEHAVIORAL: MEP Operant Up-conditioning of the Wrist Extensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT