pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Gastric Insufflation During Facemask Ventilation at Different Levels of End-expiratory Pressure in Obese Patients
Status: COMPLETED
Conditions: Gastric Insufflation|Face-mask Ventilation|Obese|Positive End Expiratory Pressure
Interventions: OTHER: zero PEEP|OTHER: low PEEP|OTHER: high PEEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Delaying the Superficial Inferior Epigastric Artery (SIEA) Flap and Determining the Change in SIEA Diameter and Blood Flow
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: PROCEDURE: Delay procedure of SIEA flap.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet-rich Fibrin Versus HIFU in Management of Stress Urinary Incontinence
Status: UNKNOWN
Conditions: Stress Urinary Incontinence
Interventions: PROCEDURE: HIFU|PROCEDURE: Fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ib/II Study of INC280 + PDR001 or PDR001 Single Agent in Advanced HCC
Status: COMPLETED
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: Spartalizumab|DRUG: Capmatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stimulating After Recovery From Traumatic Brain Injury
Status: NOT_YET_RECRUITING
Conditions: TBI (Traumatic Brain Injury)
Interventions: COMBINATION_PRODUCT: External non-invasive stimulation|BEHAVIORAL: COGED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study Assessing the Efficacy of Combined Use of Clascoterone 1% Cream and Duac Gel (Benzoyl Peroxide/Clindamycin) for the Treatment of Acne
Status: ACTIVE_NOT_RECRUITING
Conditions: Acne Vulgaris
Interventions: DRUG: Winlevi (clascoterone) 1% & Duac gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EDOF and Multifocal IOL Study
Status: COMPLETED
Conditions: Age-related Cataract
Interventions: PROCEDURE: phacoemulsification and intraocular lens implantation|DEVICE: intraocular lens implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proton Therapy and Bevacizumab for Primary Liver Tumors
Status: TERMINATED
Conditions: Liver Cancer|Hepatocellular Carcinoma|Cholangiocarcinoma
Interventions: DRUG: Bevacizumab|RADIATION: Proton Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Seasonal Malaria Chemoprevention Plus Azithromycin in African Children
Status: COMPLETED
Conditions: Malaria|Respiratory Infections
Interventions: DRUG: Sulphadoxine-Pyrimethamine+ Amodiaquine+ Azithromycin|DRUG: Sulphadoxine-pyrimethamine + amodiaquine + placebo azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Changes in Bacterial Flora Among Patients With Pelvic Bedsores: a Prospective Pilot Study
Status: COMPLETED
Conditions: Bedsore
Interventions: BIOLOGICAL: 3mm tissue punch biopsy|BIOLOGICAL: Superficial bedsore sample|BIOLOGICAL: Stool sample|BIOLOGICAL: Urine sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Indoximod in Combination With (7+3) Chemotherapy in Patients With Newly Diagnosed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Idarubicin|DRUG: Cytarabine|DRUG: Indoximod Freebase|DRUG: Indoximod HCL F1|DRUG: Indoximod HCL F2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Satisfaction of Using OmniPod System Compared With Conventional Insulin Pump in Adults With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: OmniPod system|DEVICE: Patient's conventional pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Efficacy of QGE031 in Atopic Dermatitis Patients
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: QGE031|DRUG: Placebo|DRUG: Cyclosporine A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HIIT and MICT on Nitric Oxide-mediated Erythrocyte Rheology
Status: UNKNOWN
Conditions: Exercise|Interval Training
Interventions: BEHAVIORAL: High intensity-interval training (HIIT)|BEHAVIORAL: Moderate intensity-continuous (MICT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DA-EDOCH14-R in Poor-prognosis Diffuse Large B-cell Lymphoma
Status: UNKNOWN
Conditions: Diffuse Large B-Cell Lymphoma (DLBCL)
Interventions: DRUG: Dexamethasone and dose-dense immunochemoterapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes After Sacrocolpopexy With and Without Burch to Prevent Stress Urinary Incontinence in 3rd and 4th Degree Apical Uterine Prolapse
Status: COMPLETED
Conditions: Prolapse
Interventions: PROCEDURE: Burch|PROCEDURE: Abdominal Sacrocolpopexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Use of a Novel Computerized Decision Aid for Prenatal Aneuploidy Screening
Status: COMPLETED
Conditions: Aneuploidy|Pregnancy Complications
Interventions: OTHER: iPad-based decision aid|OTHER: Genetic counseling appointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of UC-MSCs in Patients With Plaque Psoriasis
Status: UNKNOWN
Conditions: Moderate and Severe Plaque Psoriasis
Interventions: BIOLOGICAL: Low-dose UC-MSCs|BIOLOGICAL: High-dose UC-MSCs|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3-month Screening Biopsy to Optimize the Immunosuppression in Renal Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Transplantation
Interventions: DRUG: Corticosteroid boluses Methylprednisolone|OTHER: No therapeutic modification|OTHER: Stop maintenance corticotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Evaluation of Postoperative Antibiotics in Non-Infected Mandible Fractures
Status: UNKNOWN
Conditions: Jaw Fractures|Infection
Interventions: DRUG: Antibiotic treatment (Unasyn or Cleocin)|DRUG: Antibiotic treatment (Augmentin or Cleocin)|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Natural Ingredient on Appetite Regulation
Status: COMPLETED
Conditions: Appetite Regulation|Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Dietary supplement consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Paracetamol as Preemptive Analgesia for Labor Pain
Status: COMPLETED
Conditions: Labor Pain
Interventions: DRUG: paracetamol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Follow-Up Study of Risdiplam in Participants With Spinal Muscular Atrophy (SMA)
Status: RECRUITING
Conditions: Spinal Muscular Atrophy
Interventions: DRUG: Risdiplam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aerobic Exercise Verus Acupuncture on the Quality of Life in Women Suffering From Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: Aerobic excise|OTHER: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Adenovirus CCL-21 Transduced MART-1/gp100/Tyrosinase/NY-ESO-1 Peptide-Pulsed Dendritic Cells Matured
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: Autologous dendritic cell-adenovirus CCL21 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Rilvegostomig|DRUG: Volrustomig|DRUG: FOLFOX|DRUG: XELOX|DRUG: AZD7789|DRUG: AZD0901|DRUG: 5-Fluorouracil|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alcat Based Elimination Diet for the Treatment of Irritable Bowel Syndrome; a Randomized Double Blind Sham Control Trial
Status: COMPLETED
Conditions: IBS - Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Alcat based personal diet|DIETARY_SUPPLEMENT: Standard balanced diet|OTHER: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Chest Physiotherapy in Infants With Acute Viral Bronchiolitis
Status: COMPLETED
Conditions: Viral Bronchiolitis
Interventions: PROCEDURE: Chest physiotherapy - Conventional|PROCEDURE: Chest physiotherapy - actual techniques|PROCEDURE: 3-Airway suction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Plasma Concentrations During Continuous Renal Replacement Therapy With a High Adsorption Membrane (oXiris®)
Status: COMPLETED
Conditions: Hemodiafiltration|Sepsis|Acute Kidney Injury
Interventions: DEVICE: Continuous venovenous hemodiafiltration with high adsorption membrane (oXiris®)|DRUG: Antibiotics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ubenimex in Adult Patients With Lymphedema of The Lower Limb (ULTRA)
Status: COMPLETED
Conditions: Lymphedema
Interventions: DRUG: ubenimex|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Manual Dexterity and Oculomotor Control in Schizophrenia"
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DEVICE: Manual dexterity|DEVICE: Oculomotor movements|DEVICE: TMS coupled to EMG recording|OTHER: Psychopathological evaluations|OTHER: Neuropsychological evaluations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Exposed Versus Buried Intramedullary K-wires for Pediatric Forearm Fractures
Status: COMPLETED
Conditions: Forearm Fracture
Interventions: DEVICE: buried intramedullary K-wire|DEVICE: exposed intramedullary K-wire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Influences of Different Temporary Cement on Retention Rate of Temporary Crowns
Status: UNKNOWN
Conditions: MTA|Calcium Hydroxide|Dental Crown
Interventions: PROCEDURE: Temporary cement based on Calcium Hydroxide|PROCEDURE: MTA temporary cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Variable Approaches of Intradiscal O3-O2 Injection
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: Classic postrolateral extraarticular percutaneous approach for O3 injection|PROCEDURE: Postrolateral transforaminal approach (Yess approach ) for O3 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Combretastatin and Paclitaxel/Carboplatin in the Treatment of Anaplastic Thyroid Cancer
Status: TERMINATED
Conditions: Anaplastic Thyroid Cancer
Interventions: DRUG: CA4P|DRUG: paclitaxel|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured From the Onset of the QRS Complex to the End of the T Wave Corrected for Heart Rate)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Dexpramipexole|DRUG: Dexpramipexole|DRUG: Dexpramipexole Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acetazolamide Versus Dapagliflozin in Acute Decompensated Heart Failure Patients
Status: RECRUITING
Conditions: Acute Decompensated Heart Failure
Interventions: DRUG: Acetazolamide|DRUG: Dapagliflozin 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Testing Radium-223 Dichloride in Relapsed Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Radium-223 dichloride (Xofigo, BAY88-8223)|DRUG: Placebo|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cosopt Versus Xalatan
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: timolol maleate 0.5%|DRUG: dorzolamide/timolol maleate fixed combination|DRUG: latanoprost 0.005%|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab With or Without Ipilimumab or Chemotherapy in Treating Patients With Previously Untreated Stage I-IIIA Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage I Lung Non-Small Cell Cancer AJCC v7|Stage IA Lung Non-Small Cell Carcinoma AJCC v7|Stage IB Lung Non-Small Cell Carcinoma AJCC v7|Stage II Lung Non-Small Cell Cancer AJCC v7|Stage IIA Lung Non-Small Cell Carcinoma AJCC v7|Stage IIB Lung Non-Small Cell Carcinoma AJCC v7|Stage IIIA Lung Non-Small Cell Cancer AJCC v7
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Docetaxel|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization of Crohn's Disease at Confocal Laser Endomicroscopy (CLE) and Related to Disease Activity
Status: COMPLETED
Conditions: Crohn Disease
Interventions: DEVICE: CLE ileocolonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Development of Treatment Algorithm for Eradication of Helicobacter Pylori Based on Antibiotic Susceptibility Test
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: eradication of Helicobacter pylori
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suspicion of Non IgE-mediated Cow's Milk Protein Allergy: Prevalence and Evolution
Status: COMPLETED
Conditions: Food Allergy in Infants|Proctocolitis|Atopic Dermatitis|Reflux, Gastroesophageal|Tolerance
Interventions: OTHER: oral food challenge 1|OTHER: oral food challenge 2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 1b Food Based Modulation of Biomarkers in Human Tissues at High-Risk for Oral Cancer.
Status: COMPLETED
Conditions: Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma|Salivary Gland Squamous Cell Carcinoma|Stage 0 Hypopharyngeal Cancer|Stage 0 Laryngeal Cancer|Stage 0 Lip and Oral Cavity Cancer|Stage 0 Nasopharyngeal Cancer|Stage 0 Oropharyngeal Cancer|Stage 0 Paranasal Sinus and Nasal Cavity Cancer|Stage I Salivary Gland Cancer|Stage I Squamous Cell Carcinoma of the Hypopharynx|Stage I Squamous Cell Carcinoma of the Larynx|Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage I Squamous Cell Carcinoma of the Nasopharynx|Stage I Squamous Cell Carcinoma of the Oropharynx|Stage I Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage I Verrucous Carcinoma of the Larynx|Stage I Verrucous Carcinoma of the Oral Cavity|Stage II Salivary Gland Cancer|Stage II Squamous Cell Carcinoma of the Hypopharynx|Stage II Squamous Cell Carcinoma of the Larynx|Stage II Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage II Squamous Cell Carcinoma of the Nasopharynx|Stage II Squamous Cell Carcinoma of the Oropharynx|Stage II Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage II Verrucous Carcinoma of the Larynx|Stage II Verrucous Carcinoma of the Oral Cavity|Stage III Salivary Gland Cancer|Stage III Squamous Cell Carcinoma of the Hypopharynx|Stage III Squamous Cell Carcinoma of the Larynx|Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage III Squamous Cell Carcinoma of the Nasopharynx|Stage III Squamous Cell Carcinoma of the Oropharynx|Stage III Verrucous Carcinoma of the Larynx|Stage III Verrucous Carcinoma of the Oral Cavity|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IVA Salivary Gland Cancer|Stage IVA Squamous Cell Carcinoma of the Larynx|Stage IVA Oral Cavity Squamous Cell Carcinoma|Stage IVA Squamous Cell Carcinoma of the Oropharynx|Stage IVA Nasal Cavity and Paranasal Sinus Cancer|Stage IVA Verrucous Carcinoma of the Larynx|Stage IVA Verrucous Carcinoma of the Oral Cavity|Stage IVB Salivary Gland Cancer|Stage IVB Squamous Cell Carcinoma of the Larynx|Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Oropharynx|Stage IVB Oral Cavity Squamous Cell Carcinoma|Stage IVB Verrucous Carcinoma of the Larynx|Stage IVB Verrucous Carcinoma of the Oral Cavity|Stage IVC Salivary Gland Cancer|Stage IVC Squamous Cell Carcinoma of the Larynx|Stage IVC Oral Cavity Squamous Cell Carcinoma|Stage IVC Squamous Cell Carcinoma of the Oropharynx|Paranasal Sinus and Nasal Cavity Squamous Cell Carcinoma|Stage IVC Verrucous Carcinoma of the Larynx|Stage IVC Verrucous Carcinoma of the Oral Cavity|Tongue Cancer
Interventions: OTHER: placebo|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration|DRUG: chemoprevention|DRUG: chemoprevention|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Pre-emptive Analgesia in Children With Molar-incisor Hypomineralization (MIH)
Status: UNKNOWN
Conditions: Pain|Anxiety
Interventions: DRUG: Ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Combined Dapagliflozin and Exenatide Versus Dapagliflozin and Placebo on Ectopic Lipids in Patients With Uncontrolled Type 2 Diabetes Mellitus.
Status: COMPLETED
Conditions: Steatosis, Liver|Type2 Diabetes
Interventions: DRUG: Exenatide|DRUG: Exenatide matching Placebo|DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Intravenous Ascorbic Acid for Advanced Non-Small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Ascorbic acid|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Investigation of a Monofocal Toric Intra Ocular Lens (IOL) in Cataractous Eyes
Status: COMPLETED
Conditions: Cataract|Lens Opacities|Astigmatism
Interventions: DEVICE: POD T 49P implantation experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Motivational Interviewing Based on the COM-B Model
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer
Interventions: OTHER: Motivational Interviewing Based on the COM-B Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Research Study to Test Safety and Effectiveness of Investigational Drug in Patients With Trigeminal Neuralgia
Status: COMPLETED
Conditions: Trigeminal Neuralgia
Interventions: DRUG: lamotrigine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Processing Intervention for Trauma, HIV/STI Risks, and Substance Use Among Native Women
Status: COMPLETED
Conditions: Post Traumatic Stress Disorders|Unsafe Sex|Substance Use Disorders
Interventions: BEHAVIORAL: Cognitive Processing Therapy-Cognitive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: rTMS for Relieving Chronic OA Pain
Status: WITHDRAWN
Conditions: Chronic Pain|Osteo Arthritis Knee
Interventions: DEVICE: Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study To Evaluate Optical Frequency Domain Imaging For Diagnosis Of Central Airway Disease
Status: WITHDRAWN
Conditions: Squamous Cell Lung Cancer|Lung Cancer|Pulmonary Disease
Interventions: DEVICE: Optical Frequency Domain Imaging (OFDI) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Adenovirus Encoding Rat HER-2 in Patients With Metastatic Breast Cancer (AdHER2.1)
Status: COMPLETED
Conditions: Metastatic Breast Cancer|Recurrent Breast Cancer
Interventions: BIOLOGICAL: adenoviral vector encoding rat Her-2/neu
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Peg-Interferon Alpha-2a Plus Ribavirin in Genotype 1 Chronic Hepatitis C Participants Co-Infected With Human Immunodeficiency Virus
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Peg-Interferon Alpha-2A|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Angiotensin Type I Receptor in the Regulation of Human Coronary Vascular Function
Status: COMPLETED
Conditions: Atherosclerosis|Heart Failure, Congestive|Hypertension|Myocardial Infarction
Interventions: DRUG: Angiotensin II type 1 receptor antagonists
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: HIDRATA Study: Efficacy of a Hydration Protocol in Nulliparous Women During Labor
Status: UNKNOWN
Conditions: Labor Long|Nulliparity|Premature Rupture of Membrane|Pregnancy, Prolonged|Pregnancy
Interventions: PROCEDURE: optimal|PROCEDURE: variability
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhalation of Vapor With Medication (Diclofenac Sodium, Menthol, Methyl Salicylate and N-Acetyl Cysteine) Reduces Oxygen Need and Hospital Stay in COVID-19 Patients - A Case Control Study
Status: COMPLETED
Conditions: Covid19
Interventions: COMBINATION_PRODUCT: Menthol 0.02%, Methyl salicylate 0.05%, N- Acetyl cysteine 1.2 gm%, and Diclofenac sodium 1gm%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2b Study To Evaluate The Efficacy And Safety Profile Of PF-06651600 And PF-06700841 In Active Non-segmental Vitiligo Subjects
Status: COMPLETED
Conditions: Active Non-segmental Vitiligo
Interventions: DRUG: PF-06651600|DRUG: PF-06651600|DRUG: PF-06651600|DRUG: PF-06651600|DRUG: PF-06651600|DRUG: placebo|DRUG: PF06700841|DEVICE: narrow-band UVB phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Whey Protein Supplementation in High School Athletes
Status: ACTIVE_NOT_RECRUITING
Conditions: Body Weight Changes|Athletic Performance|Recovery|Sleep
Interventions: DIETARY_SUPPLEMENT: Whey Protein Supplement|DIETARY_SUPPLEMENT: Carbohydrate Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Rhomboid Intercostal and Subserratus Plane Block
Status: COMPLETED
Conditions: Cholecystectomy|Postoperative Pain|Nerve Block
Interventions: OTHER: RIIS|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motivational Interviewing to Engage Operations Enduring Freedom and Iraqi Freedom (OEF/OIF) Veterans in Mental Health Treatment
Status: COMPLETED
Conditions: Combat Disorders|Stress Disorders, Post-Traumatic|Depression|Substance-Related Disorders
Interventions: BEHAVIORAL: telephone-administered motivational interviewing|BEHAVIORAL: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Single-Ascending-Dose Study of BIIB076 in Healthy Volunteers and Participants With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease|Healthy Volunteer
Interventions: DRUG: BIIB076|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Neuromuscular Electrical Stimulation (NMES) on the Renal Function and Renal Blood Flow
Status: UNKNOWN
Conditions: Renal Injury
Interventions: PROCEDURE: neuromuscular electrical stimulation (NMES) in addition to routine hospital care|PROCEDURE: routine hospital care without NMES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Palivizumab for Prevention of Severe Respiratory Syncytial Virus Infection in Russian Children
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infection|Premature Birth|Bronchopulmonary Dysplasia|Congenital Heart Disease
Interventions: BIOLOGICAL: palivizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study for the Recording of Adherence to Treatment With Perindopril/Indapamide/Amlodipine Fixed Dose Combination
Status: COMPLETED
Conditions: Adherence to Medication Regime|Hypertensive Disease
Interventions: DRUG: Perindopril/Indapamide/Amlodipine fixed dose combination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Adalimumab in Subjects With Moderately to Severely Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: BIOLOGICAL: adalimumab|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test if Fremanezumab Reduces Pain in Patients With Interstitial Cystitis-Bladder Pain Syndrome
Status: WITHDRAWN
Conditions: Interstitial Cystitis
Interventions: DRUG: fremanezumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Positioning Navigation Template for Assisting the Placement of Modular Hemipelvic Endoprostheses for Patients Undergoing Pelvic Bone Tumor Resection.
Status: COMPLETED
Conditions: Pelvic Tumor
Interventions: DEVICE: Acetabular reconstruction after tumor resection.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Comparing Monocryl and Dermabond Closure Versus Staple Closure in Total Hip Arthroplasty
Status: COMPLETED
Conditions: Unilateral Primary Osteoarthritis, Unspecified Hip
Interventions: PROCEDURE: Monocryl closure|PROCEDURE: Vicryl and Staple closure|PROCEDURE: Tegaderm dressing|PROCEDURE: Gauze dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Artificial Pancreas With and Without a Meal Detection Module on Glycemic Control in Adolescents With Type 1 Diabetes After a Missed Bolus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Closed Loop Delivery|DEVICE: Closed Loop Delivery with Meal Detection Module|DEVICE: Conventional Pump Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery and Whole Brain Radiotherapy (RT) Versus Whole Brain Radiotherapy (RT) and Radiosurgery for 1-3 Resectable Brain Metastases
Status: WITHDRAWN
Conditions: Metastases|Cancer
Interventions: OTHER: surgery|RADIATION: radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Fenofibrate on Sleep Apnea Syndrome
Status: TERMINATED
Conditions: Dyslipidemia|Sleep Apnea Syndrome|Overweight|Obesity
Interventions: DRUG: Placebo|DRUG: Fenofibrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Approach Integrating Magnetic Resonance Imaging (MRI) Data and Artificial Intelligence for Predicting the Success Rate of Vaginal Delivery in Pregnant Women
Status: NOT_YET_RECRUITING
Conditions: Vaginal Delivery
Interventions: DEVICE: Mri scan of fetal head and pelvis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Regional Anesthesia in Colon Rectal Surgery
Status: WITHDRAWN
Conditions: Colon Cancer
Interventions: PROCEDURE: Regional anesthesia and analgesia|DRUG: general anesthesia followed by opioid analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of SAR342434 to Humalog as the Rapid Acting Insulin in Adult Patients With Type 1 Diabetes Mellitus Also Using Insulin Glargine
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: SAR342434|DRUG: Humalog|DRUG: Insulin glargine HOE901
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Botulinum Toxin Type A for Injection（HengLi®）for Prophylactic Treatment of Chronic Migraine
Status: UNKNOWN
Conditions: Chronic Migraine
Interventions: DRUG: Botulinum Toxin Type A for Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Perindopril 5 mg / Indapamide 1.25 mg / Amlodipine 5 mg Fixed Combination in Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Fixed [Per/Ind/Aml]|DRUG: Free [Per/Ind + Aml]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Contamination of Hospital Scrubs
Status: COMPLETED
Conditions: Bacterial Contamination
Interventions: OTHER: Antimicrobial impregnated scrubs|OTHER: Non-impregnated scrubs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Transendocardial Autologous Cells (hMSC) or (hMSC) and (hCSC) in Ischemic Heart Failure Trial.
Status: WITHDRAWN
Conditions: Chronic Ischemic Left Ventricular Dysfunction|Myocardial Infarction
Interventions: DRUG: Autologous hMSCs|DRUG: Autologous Human C-Kit CSCs II|DRUG: Placebo|DEVICE: Biosense Webster MyoStar NOGA Injection Catheter System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: AMG-479 in Treating Patients With Advanced Solid Tumors or Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Prostate Cancer|Sarcoma|Small Intestine Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: ganitumab|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D Replacement on Maternal and Neonatal Outcomes
Status: COMPLETED
Conditions: Hypovitaminosis D|Pregnancy Complications|Infant, Newborn, Diseases
Interventions: DIETARY_SUPPLEMENT: Euro D|DIETARY_SUPPLEMENT: Euro D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Brain Stimulation Through Imaging
Status: RECRUITING
Conditions: Depression|Depressive Disorder, Treatment-Resistant|COVID Stress
Interventions: BEHAVIORAL: Psychological / Functional Assessment|OTHER: Structural and Functional MRI|DEVICE: Transcranial Magnetic Brain Stimulation and MR Image Guidance|DEVICE: Transcranial Electrical Stimulation (tES)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacodynamic Study of CK-2017357 in Patients With Generalized Myasthenia Gravis
Status: TERMINATED
Conditions: Myasthenia Gravis
Interventions: DRUG: Placebo|DRUG: 250 mg CK-2017357|DRUG: 500 mg CK-2017357
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perifollicular Vascularity Assessment in in-Vitro Fertilization
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: Controlled ovarian stimulation, perifollicular vascularity assessment, IVF, embryo transfer.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Intrathoracic Pressure Regulation on Decreased Cerebral Perfusion (4hour)
Status: TERMINATED
Conditions: Head Injury|Intracranial Pathology|Compromised Cerebral Perfusion
Interventions: DEVICE: ITPR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy-induced Peripheral Neuropathy (CIPN) on Motor and Sensory Function
Status: COMPLETED
Conditions: Cancer|Chemotherapy-induced Peripheral Neuropathy|Chemotherapeutic Toxicity|Breast Cancer|Breast Neoplasms|Colon Neoplasm|Colo-rectal Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Examining the Link Between Obesity, Inflammation, and Response to Asthma Medications
Status: COMPLETED
Conditions: Asthma|Obesity
Interventions: DRUG: Beclomethasone dipropionate HFA|DRUG: Tiotropium bromide|DRUG: Salmeterol xinafoate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Refractive Status and Accommodation Response Under Different Experimental Conditions.
Status: RECRUITING
Conditions: Accommodation Disorder|Accommodative Fatigue|Accommodative Inertia
Interventions: DEVICE: Visual acuity|DEVICE: Objective refraction|DEVICE: Objective monocular accommodation amplitude measurement|DEVICE: Subjective monocular accommodation amplitude measurement with the "Push-Up" method|DEVICE: Subjective monocular accommodation facility measurement with the "Rock" method:|OTHER: CISS Questionnaire|OTHER: Difficulty assessment questionnaire|OTHER: Subjective evaluation questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Linked Color Imaging to Differentiate H. Pylori Associated Gastritis and Gastric Atrophy
Status: COMPLETED
Conditions: Gastritis|Helicobacter Pylori Associated Gastritis|Atrophic Gastritis
Interventions: DEVICE: WLE and then LCI|DEVICE: LCI and then WLE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of the Use of Oral Posaconazole (POS) in the Treatment of Asymptomatic Chronic Chagas Disease (P05267)
Status: COMPLETED
Conditions: Chagas Disease
Interventions: DRUG: Posaconazole|DRUG: Placebo for posaconazole|DRUG: Benznidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Duloxetine in Elderly Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: Duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GPR109A and Parkinson's Disease: Role of Niacin in Outcome Measures
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DIETARY_SUPPLEMENT: niacin|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Toripalimab,Celecoxib and Regorafenib in the Treatment of Refractory Advanced Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer|Liver Metastases|MSS
Interventions: DRUG: Rego+Tori+Cele
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biofilm Modified Macrophage Phenotype and Function in Diabetic Wound Healing
Status: TERMINATED
Conditions: Wound|Bacterial Infections|Diabetes Mellitus|Infected Ulcer of Skin
Interventions: DIAGNOSTIC_TEST: Finger prick test for HbA1c measurement|PROCEDURE: Punch Biopsy|OTHER: Vac Sponge Collection|OTHER: Ankle Brachial Index
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interest of CALR Allele Burden in Diagnosis and Follow-up of Patients With CALR Mutated Myeloproliferative Syndromes (CALRSUIVI)
Status: RECRUITING
Conditions: Myeloproliferative Neoplasm|Essential Thrombocythemia|Primary Myelofibrosis, Prefibrotic Stage|Primary Myelofibrosis, Fibrotic Stage
Interventions: BIOLOGICAL: CALR allele burden quantification
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of BI 655075 (Idarucizumab) Administered Alone or With Dabigatran Etexilate in Japanese Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo to dose|DRUG: Idarucizumab|DRUG: Placebo to Idarucizumab|DRUG: dabigatran|DRUG: Idarucizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Loop Ileostomy With Colonic Lavage for Fulminant Clostridium Difficile Colitis
Status: TERMINATED
Conditions: Fulminant Clostridium Difficile Colitis
Interventions: PROCEDURE: Loop Ileostomy with colonic lavage|PROCEDURE: Total Abdominal Colectomy with end ileostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Efficacy of the S.M.A.R.T. RADIANZ™ Vascular Stent System in the Treatment of Iliac and Femoropopliteal Lesions Via Transradial Access
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: S.M.A.R.T. RADIANZ™ Vascular Stent System|DEVICE: BRITE TIP RADIANZ™ Guiding Sheath|DEVICE: SABERX RADIANZ™ PTA Balloon Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Work Package 2 Phase 1 - Beverages Study
Status: COMPLETED
Conditions: Glycemic Index|Overweight and Obesity
Interventions: OTHER: Comparison of sweetener blends in liquid form (cross-over study)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Observational Studies in Cancer Associated Thrombosis for Rivaroxaban - United States Cohort
Status: COMPLETED
Conditions: Treatment of Venous Thromboembolism in Cancer Patients|Prophylaxis of Recurrent Venous Thromboembolism in Cancer Patients
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Low molecular weight heparin (LMWH)|DRUG: Direct Oral Anticoagulants (DOAC)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Goal-directed Fluid Therapy Based on Stroke Volume Variation on Metabolic Acidosis in Patients Undergoing Brain Tumor Surgery
Status: COMPLETED
Conditions: Brain Tumor
Interventions: DRUG: SVV|DRUG: CVP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Local Gentamicin Application to Reduce Postoperative Infection Rate
Status: COMPLETED
Conditions: Surgical Wound Infection
Interventions: DEVICE: Collagen-gentamicin sponge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: BLU-5937: First-in-Human, Single and Multiple Doses Escalation, Safety, Tolerability, Pharmacokinetics and Food Effect
Status: COMPLETED
Conditions: Cough
Interventions: DRUG: BLU-5937|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Feasibility Trial of the SafeLM Supraglottic Airway (SGA)
Status: RECRUITING
Conditions: Anesthesia
Interventions: DEVICE: SafeLM as a supraglottic airway device with video capability|DEVICE: SafeLM as a supraglottic airway device without video capability|DEVICE: SafeLM as a conduit for intubation using an endotracheal tube with video capability|DEVICE: SafeLM as a conduit for intubation using a bougie with video capability
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Light Conditions on the Efficacy of Multifocal Intraocular Lens Implantation in Activities of Daily Living
Status: COMPLETED
Conditions: Presbyopia|Near Vision|Reading|Daily Activities|Multifocal Intraocular Lens|Cataract
Interventions: OTHER: ADL performance
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cervical Preparation With Mifepristone Prior to Osmotic Dilators
Status: TERMINATED
Conditions: Second Trimester Abortion
Interventions: DRUG: Mifepristone 200 MG|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Trial Evaluating Hyperthermic Intraperitoneal Chemotherapy in Upfront Treatment of Stage IIIC Epithelial Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Neoplasms
Interventions: PROCEDURE: Cytoreductive Surgery and HIPEC|PROCEDURE: CRS alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D on Ovulation Rate in Women With Polycystic Ovary Syndrome
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome|Anovulation
Interventions: DIETARY_SUPPLEMENT: Vitamin D|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Application LED Therapy and Laser Therapy in Facial Rejuvenation
Status: COMPLETED
Conditions: Aging|Wrinkles
Interventions: DEVICE: Infrared Laser + Amber LED|DEVICE: Amber LED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT