pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Use of Probiotics to Reduce Infections, Death and ESBL Colonisation
Status: ACTIVE_NOT_RECRUITING
Conditions: Neonatal Sepsis
Interventions: BIOLOGICAL: Labinic (R) probiotic mixture|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Block Injection of an Anti Inflammatory Medicine in Patients With Mandibular Dental Pain
Status: COMPLETED
Conditions: Symptomatic Irreversible Pulpitis
Interventions: DRUG: Ketorolac Tromethamine|BEHAVIORAL: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Therapeutic Learning for PTSD
Status: RECRUITING
Conditions: PTSD|Post Traumatic Stress Disorder
Interventions: DRUG: L-DOPA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Thoracic Excluder Endoprosthesis to Treat Descending Thoracic Aortic Diseases
Status: UNKNOWN
Conditions: Descending Thoracic Aortic Disease
Interventions: DEVICE: Thoracic EXCLUDER Endoprosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paxil Japanese Post Marketing Paediatric Study in Depression (Double-blind, Placebo Controlled Study)
Status: TERMINATED
Conditions: Depressive Disorder
Interventions: DRUG: paroxetine 10mg tablet|DRUG: paroxetine 20mg tablet|DRUG: matched placebo to paroxetine 10mg|DRUG: matched placebo to paroxetine 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Solifenacin Succinate in Combination With Tamsulosin for the Treatment of Residual Overactive Bladder Symptoms (OAB) in Men.
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DRUG: solifenacin succinate|DRUG: tamsulosin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Immunotherapy in Patients With Carcinomas Arising From the Renal Medulla
Status: RECRUITING
Conditions: Carcinomas|Renal Medullary Carcinoma
Interventions: DRUG: Nivolumab|DRUG: Relatlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Insulin Glargine at Bedtime or in AM Versus NPH
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: 1- Insulin glargine QHS|DRUG: 2 - Insulin glargine QAM|DRUG: 3 - NPH insulin QHS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testosterone for Peripheral Vascular Disease
Status: COMPLETED
Conditions: Hypogonadism|Peripheral Vascular Disease|Type 2 Diabetes
Interventions: DRUG: Testosterone|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyporeactivity and Gulf War Illness
Status: COMPLETED
Conditions: Gulf War Syndrome|Chronic Fatigue Syndrome|Post-Traumatic Stress Disorder
Interventions: DRUG: Graded dobutamine infusions|DRUG: Graded phenylephrine injections|BEHAVIORAL: Psychosocial challenge involving socioevaluative public speaking
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Hydrocortisone Per-treatment Decrease Side Effects of Protamine Sulfate
Status: COMPLETED
Conditions: Blood Pressure|Heart Rate|Airway Pressure
Interventions: DRUG: Hydrocortisone 200mg IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Pharmacological Study of MT-3921 in Subjects With HTLV-1 Associated Myelopathy (HAM)
Status: COMPLETED
Conditions: HTLV-1-Associated Myelopathy (HAM)
Interventions: BIOLOGICAL: MT-3921|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Long-Term Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Advance)
Status: ACTIVE_NOT_RECRUITING
Conditions: Acromegaly
Interventions: DRUG: Paltusotine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Cyclosporin A 0.05% Eye Drops for Management of Symptomatic Acquired Punctal Stenosis. A Prospective, Controlled Clinical Study.
Status: COMPLETED
Conditions: Management of Punctal Stenosis
Interventions: DRUG: 0.05% cyclosporin (Restasis®, Allergan Inc)|DEVICE: mini-monoka stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase I Stereotactic Body Radiation for Metastatic or Recurrent Platinum-Resistant Ovarian Cancer
Status: TERMINATED
Conditions: Recurrent Ovarian Epithelial Cancer|Recurrent Ovarian Germ Cell Tumor|Malignant Tumor of Peritoneum|Stage IV Ovarian Epithelial Cancer|Stage IV Ovarian Germ Cell Tumor
Interventions: RADIATION: stereotactic body radiation therapy|PROCEDURE: positron emission tomography|PROCEDURE: computed tomography|OTHER: questionnaire administration|DRUG: fludeoxyglucose F 18
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ridge Augmentation Comparing a Block Allograft to a Demineralized Bone Matrix Allograft.
Status: COMPLETED
Conditions: Alveolar Process Defect
Interventions: PROCEDURE: Block Allograft plus Matrix Allograft|PROCEDURE: Moldable Matrix Allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraarticular Ozone Therapy for Pain Control in Osteoarthritis of the Knee
Status: TERMINATED
Conditions: Osteoarthritis of the Knee
Interventions: OTHER: ozone-oxygen mixture|OTHER: placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of the Cystic Fluid Interleukins and Tumor Necrosis Factor (TNF) Levels in Characterizing Pancreatic Cysts Detected by Endoscopic Ultrasound (EUS)
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: PROCEDURE: EUS with fine-needle aspiration of pancreatic cyst|DIAGNOSTIC_TEST: Laboratory Blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Metformin on Patients With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Interventions: DRUG: Metformin intervention for 12 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Tolerability Study of Two Dose Regimens of CTP-543 in Adults With Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: CTP-543|DRUG: CTP-543 Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Infliximab for the Treatment of Pemphigus Vulgaris
Status: COMPLETED
Conditions: Pemphigus
Interventions: DRUG: Infliximab|OTHER: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: De-escalation of Empirical Antimicrobial Therapy Study in Severe Sepsis
Status: COMPLETED
Conditions: Severe Sepsis
Interventions: PROCEDURE: continuation of the empirical antimicrobial therapy|PROCEDURE: streamlining of the empirical antimicrobial therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Nexavar (Sorafenib, BAY 43-9006) in Patients With Advanced Refractory Cancer
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Ability of Eltrombopag to Induce Sustained Response Off Treatment in Subjects With ITP
Status: COMPLETED
Conditions: Immune Thrombocytopenic Purpura (ITP)
Interventions: DRUG: eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Therapy in Lupus Nephropathy
Status: COMPLETED
Conditions: Nephrotic Syndrome|Systemic Lupus Erythematosus
Interventions: DRUG: prednisone|DRUG: cyclophosphamide|DRUG: cyclosporin A
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Bioequivalence of 2 Fixed Dose Combination (FDC) Tablets of Canagliflozin and Metformin Immediate Release (IR) (150 mg/850 mg) With Respect to the Individual Components of Canagliflozin (1 x 300 mg) and Metformin IR Tablets (2 x 850 mg) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: A (canagliflozin and metformin IR individual tablets) / B (canagliflozin/metformin IR FDC tablets)|DRUG: B (canagliflozin/metformin IR FDC tablets / A (canagliflozin and metformin IR individual tablets)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label, Dose-finding Study to Determine Antibody Response to G17DT Treatment in Patients With Gastric Cancer.
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: BIOLOGICAL: G17DT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Practice-Based Intervention To Improve Care for a Diverse Population Of Women With Urinary Incontinence
Status: RECRUITING
Conditions: Urinary Incontinence
Interventions: OTHER: Academic Detailing|OTHER: Electronic Clinical Decision Support|OTHER: APP Co-management|OTHER: Electronic Referral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 24-hr Intraocular Pressure (IOP) Patterns of Glaucoma Patients After Selective Laser Trabeculoplasty (SLT)
Status: WITHDRAWN
Conditions: Glaucoma
Interventions: DEVICE: SLT (selective laser trabeculoplasty ) SENSIMED Triggerfish
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CSP #562 - The VA Keratinocyte Carcinoma Chemoprevention Trial
Status: COMPLETED
Conditions: Carcinoma, Basal Cell|Carcinoma, Squamous Cell|Skin Neoplasms|Skin Diseases|Neoplasms, Basal Cell|Neoplasms, Squamous Cell|Carcinoma
Interventions: DRUG: 5-fluorouracil|DRUG: Placebo, vehicle control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of HIL-214 With Routine Pediatric Vaccines
Status: COMPLETED
Conditions: Gastroenteritis
Interventions: BIOLOGICAL: HIL-214|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigational Study of Delayed Release Metformin
Status: SUSPENDED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Metformin DR|DRUG: Metformin IR|DRUG: Metformin DR Placebo|DRUG: Metformin IR placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dorsal Penile Block for Post-Robotic Prostatectomy Foley Discomfort
Status: WITHDRAWN
Conditions: Prostate Cancer|Robotic Prostatectomy|Foley Catheter Discomfort
Interventions: DRUG: Bupivacaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LAmbre Versus AMPLATZER Amulet Left AtrIal Appendage Occluder for StRoke ProphylaxIs
Status: RECRUITING
Conditions: Left Atrial Appendage Occlusion
Interventions: DEVICE: Left Atrial Appendage Occlusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Significance of the High-risk Hpv Viral Load
Status: COMPLETED
Conditions: HPV Infections
Interventions: OTHER: 2 cervical takings and 2 sampling of blood|OTHER: 2 cervical takings and 2 sampling of blood|OTHER: 2 cervical takings and 2 sampling of blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Blood Lipopolysaccharide (LPS) Rifaximin Study
Status: COMPLETED
Conditions: Obese|Insulin Resistance|Metabolic Syndrome
Interventions: DRUG: Rifaximin SSD|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Assessment of T2345 in Ocular Hypertensive or Glaucomatous Patients
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: T2345|DRUG: Prostaglandin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Trial of LACTIN-V in Women at High Risk of HIV Acquisition
Status: COMPLETED
Conditions: Bacterial Vaginosis|HIV Infections
Interventions: DRUG: LACTIN-V|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of mHealth on Promoting Self-care Health Management Among Older Adults in the Community
Status: COMPLETED
Conditions: Telemedicine
Interventions: OTHER: mHealth application with interactivity|OTHER: mHealth application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Acute Hemodynamic Effects of Pacing the His Bundle in Heart Failure
Status: SUSPENDED
Conditions: Heart Failure, Systolic|Left Bundle Branch Block|Wide QRS Complex
Interventions: DEVICE: Temporary His bundle pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Evaluation of Three Different Universal Adhesives in Non-carious Cervical Lesions
Status: ACTIVE_NOT_RECRUITING
Conditions: Tooth Diseases
Interventions: DEVICE: Clearfil Univesal Bond|DEVICE: IBond Universal|DEVICE: G-Premio Bond
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Tenofovir/Emtricitabine in Patients Recently Infected With SARS-COV2 (Covid-19) Discharged Home
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: tenofovir disoproxil and emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Prone Position Drainage on the Efficacy of Severe Pneumonia，a Multicenter Randomized Controlled Trial
Status: UNKNOWN
Conditions: Severe Pneumonia
Interventions: BEHAVIORAL: Placed in prone position for at least 16 consecutive hours a day.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Quantification of Fecal Calprotectin Concentration Difference Between Infants Aged Under 4 Months Old Suffering From Functional Gastrointestinal Disorders (FGID) and Infants Aged Under 4 Months Old Free From Disorders : a Transversal Case-control Monocentric Study
Status: NOT_YET_RECRUITING
Conditions: Functional Gastrointestinal Disorders|Infant, Newborn, Diseases
Interventions: OTHER: Fecal calprotectin dosage|OTHER: Questionnaire and interview with parents
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Transdermal Testosterone Patches in Naturally Menopausal Women With Low Libido
Status: COMPLETED
Conditions: Hypoactive Sexual Desire Disorder
Interventions: DRUG: Testosterone Transdermal System|DRUG: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Orthostatic Intolerance in Patients With Parkinson's Disease Using Midodrine
Status: UNKNOWN
Conditions: Orthostatic Intolerance|Parkinson's Disease
Interventions: DRUG: Midodrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CTT on Renogram as an Early Marker of Significant Obstruction in Uretero-pelvic Junction Syndrome
Status: RECRUITING
Conditions: Ureteropelvic Junction Obstruction
Interventions: DEVICE: ultrasonography|DEVICE: diuretic renography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pravastatin to Prevent Preeclampsia
Status: TERMINATED
Conditions: Preeclampsia|Obstetric Labor Complications|Hypertension in Pregnancy
Interventions: DRUG: Pravastatin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dry Needling and Exercise Versus Traditional Physical Therapy for Biceps Tendinitis
Status: WITHDRAWN
Conditions: Bicep Tendinitis|Biceps; Tenosynovitis|Bicipital Tendinitis, Left Shoulder|Bicipital Tendinitis, Right Shoulder|Bicipital Tendinitis, Unspecified Shoulder|Biceps Tendon Disorder
Interventions: OTHER: Dry Needling|OTHER: Heavy Slow Load Exercise|OTHER: Rotator cuff and scapular stabilization exercise program|OTHER: Soft tissue mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Optic Nerve Ultrasound Following Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Congenital Heart Disease|Congenital Heart Defect
Interventions: DIAGNOSTIC_TEST: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tri-modality Sampling Using Radial Probe Endobronchial Ultrasound for the Diagnosis of Peripheral Pulmonary Lesions
Status: RECRUITING
Conditions: Lung Nodule
Interventions: DIAGNOSTIC_TEST: Tri-modality biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Fluid Milk in Attenuating Hyperglycemia and Hypertriglyceridemia After Meal
Status: COMPLETED
Conditions: Oral Glucose Tolerance Test|High Fat Tolerance Test
Interventions: DIETARY_SUPPLEMENT: non-fat milk|DIETARY_SUPPLEMENT: carbohydrate control beverage|DIETARY_SUPPLEMENT: caloric control beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evicel Study on the Peri-operative Bleeding in Total Knee Prothesis Surgery
Status: UNKNOWN
Conditions: Thrombosis
Interventions: DRUG: Human Fibrinogen and human thrombin (Evicel)|DRUG: Sodium Chlorure (Physiological saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Experimental Human Malaria Infection After Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria
Interventions: DRUG: Chloroquine prophylaxis|BIOLOGICAL: Immunization|BIOLOGICAL: Plasmodium falciparum Bloodstage challenge|BIOLOGICAL: Plasmodium falciparum mosquito challenge|DRUG: Malarone treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preventing Renal Functional Abnormalities With Calorie Restriction in Subjects With Abdominal Obesity and Type 2 Diabetes at Increased Renal and Cardiovascular Risk
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: OTHER: Caloric restriction|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Citalopram and Lithium for the Treatment of Depressive Mood Disorder Symptoms
Status: COMPLETED
Conditions: Major Depressive Disorder|Dysthymia|Depression Not Otherwise Specified|Borderline Personality Disorder
Interventions: DRUG: Lithium Carbonate|DRUG: Placebo|DRUG: Citalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Pharmacokinetics, Pharmacodynamics and Safety of Tiprogrel in Healthy Subjects
Status: NOT_YET_RECRUITING
Conditions: Acute Coronary Syndrome|Ischemic Stroke
Interventions: DRUG: Tiprogrel|DRUG: Tiprogrel|DRUG: Clopidogrel|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial Investigating the Pharmacokinetic Properties of FIAsp in Japanese Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: Faster-acting insulin aspart|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Blinatumomab on Minimal Residual Disease (MRD) in Diffuse Large B-Cell Lymphoma (DLBCL) Subjects Post Autologous Hematopoietic Stem Cell Transplantation (aHSCT)
Status: TERMINATED
Conditions: High-risk Diffuse Large B-cell Lymphoma
Interventions: DRUG: Blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: XELOX Plus Apatinib vs XELOX as Post-operative Chemotherapy in Locally Advanced Gastric Signet Ring Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Gastric Carcinoma
Interventions: DRUG: Apatinib|DRUG: XELOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AS703569 and Gemcitabine Combination in Advanced Malignancies
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: AS703569/gemcitabine|DRUG: AS703569/gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability and Pharmacokinetics After Multiple Doses of AZD2066 in Japanese Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD2066|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fecal Microbiota Transplantation in Diarrhea Induced by Tyrosine-kinase Inhibitors
Status: COMPLETED
Conditions: Diarrhea Caused by Drug (Disorder)|Renal Cell Cancer
Interventions: OTHER: Donor FMT|OTHER: Sham FMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fruquintinib Combined With Chemotherapy as Third-line /Third-line+ Treatment in Advanced Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced Colorectal Cancer
Interventions: DRUG: Fruquintinib Combined With Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lucentis (Ranibizumab) in Diabetic Macular Oedema: a Treatment Evaluation
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DRUG: Ranibizumab|PROCEDURE: Modified ETDRS laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study of the Histone Deacetylase Inhibitor (HDACi) JNJ 26481585 in Combination With VELCADE (Bortezomib) and Dexamethasone for Patients With Relapsed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: JNJ-2641585 / VELCADE / Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of RPh201 Treatment of Ischemic Optic Neuropathy (ION).
Status: COMPLETED
Conditions: Non-arteritic Ischemic Optic Neuropathy|Optic Nerve Injuries
Interventions: DRUG: RPh201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Local Vibrations Program of Dorsiflexor Muscles on Neuromotor Recovery in Subacute Stroke Patients.
Status: RECRUITING
Conditions: Stroke Rehabilitation
Interventions: DEVICE: Vibration|DEVICE: Sham vibration|OTHER: 10 meters Walk Test|OTHER: 2 Minute Walk Test (2MWT)|OTHER: Fugl-Meyer (FMA-LE)|OTHER: Modified Ashworth scale|OTHER: ABILOCO questionnaire|OTHER: Barthel index|OTHER: isometric ergometer|OTHER: Electromyograms (EMG)|OTHER: Traditional quantified gait analysis|OTHER: SPM - Statistical Parametric Mapping|OTHER: FACIT questionnaire (Functional Assessment of Chronic Illness Therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Exploring the Effect of Mindfulness on Quality of Life (QoL) in Spinal Cord Injury (SCI)
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries|Quality of Life
Interventions: BEHAVIORAL: Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Supplementation With a Black Pepper Extract
Status: COMPLETED
Conditions: Waist Circumference|Triglycerides|Appetite|Inflammation|Lipids
Interventions: DIETARY_SUPPLEMENT: Black pepper extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Two Pilates-based Mat Exercise Programs on the Isometric Strength of Core Muscles in Healthy Men
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BEHAVIORAL: Pilates exercise with Theraband|BEHAVIORAL: Pilates exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety/Efficacy Study of Human Umbilical Cord Mesenchymal Stem Cells Therapy (19#iSCLife®-LDP) for Lumbar Discogenic Pain
Status: RECRUITING
Conditions: Lumbar Discogenic Pain
Interventions: BIOLOGICAL: human umbilical cord mesenchymal stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Calcium Glycerophosphate (CaGP) - Fluoride Dentifrice on Dental Biofilm pH
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: calcium glycerophosphate|DRUG: no active ingredient|DRUG: fluoride|DRUG: CAGP + fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study to Evaluate the Use of the Vest® System for Treatment of Bronchiectasis Patients in the Home Setting
Status: TERMINATED
Conditions: Bronchiectasis|Bronchiectasis With Acute Exacerbation
Interventions: DEVICE: High Frequency Chest Wall Oscillation|DEVICE: Oscillating Positive Expiratory Pressure (OPEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Function With New Pediatric Oxygenator and Heparin and Non Heparin Coating in Pediatric Cardiac Surgery
Status: TERMINATED
Conditions: Acquired Platelet Function Disorder
Interventions: DEVICE: Balance surface, Carmeda heparin-coated surface|DEVICE: non -heparin extracorporeal pediatric device for operation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Magnetically Controlled Capsule Endoscopy Feasibility Study in Gastric Motility
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastroparesis|Dyspepsia
Interventions: DEVICE: Magnetically Controlled Capsule Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of CGMS vs. Self-monitoring Blood Glucose (SMBG) in Woman With Gestational Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Gestational Diabetes Mellitus in Pregnancy
Interventions: DEVICE: real time continuous glucose monitor|DEVICE: blinded continuous glucose monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Rehabilitation With Patterned Electrical Neuromuscular Stimulation for Patients With Patellofemoral Pain
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: DEVICE: PENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Needlescopic Inversion and Snaring Versus Ligation of Hernia Sac in Girls
Status: UNKNOWN
Conditions: Congenital Inguinal Hernia|Hernia Sac|Recurrent Hernia|Round Ligament; Injury|Fallopian Tube Injury|Ovarian Injury
Interventions: DEVICE: Hernia sac inversion and Snaring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maternal Pertussis Wholecell Responses
Status: COMPLETED
Conditions: Pertussis
Interventions: BIOLOGICAL: Standard of care vaccines|BIOLOGICAL: Boostagen, (BioNet-Asia)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fetal Umbilical Cord Blood (UCB) Transplant for Lysosomal Storage Diseases
Status: WITHDRAWN
Conditions: Lysosomal Storage Diseases|Inborn Errors of Metabolism
Interventions: BIOLOGICAL: ALD-601
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studying Lymph Nodes in Patients With Stage II Colon Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: GENETIC: RNA marker analysis of lymph node and primary tumors|GENETIC: microarray profiling of primary tumors|GENETIC: reverse transcriptase-polymerase chain reaction of lymph node specimens|OTHER: diagnostic laboratory RNA and DNA biomarker analysis of primary tumors|PROCEDURE: regional lymph node dissection|OTHER: lymph node staining for H&E and pancytokeratin IHC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adhesive Tape Trauma Evaluation of a New Gentle Tape in Healthy Infant Subjects
Status: COMPLETED
Conditions: Skin (FLACC Scores of Test Subjects) After Tape Removal
Interventions: DEVICE: Multi-Purpose Gentle Tape
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Reproductive and Sexual Health in People With Early Onset Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer|Colorectal Neoplasms|Colorectal Carcinoma
Interventions: DIAGNOSTIC_TEST: Hormone biomarker analysis|BEHAVIORAL: QoL Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluate the Efficacy and Safety of Xianglei Tangzu Gao for the Treatment of Wagner Grade II Diabetic Foot Ulcers
Status: RECRUITING
Conditions: Diabetic Foot Ulcer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Atelocollagen Injection in Patients With Calcific Tendinitis
Status: RECRUITING
Conditions: Calcific Tendinitis of Shoulder|Atelocollagen
Interventions: DEVICE: Atelocollagen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prospective Trial on the Clinical Feasibility of a New Full Thickness Endoscopic Plication Device for Patients With GERD.
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: PROCEDURE: endoscopic full thickness plication
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Effect of a Probiotic Mixture on Signs and Symptoms of Irritable Bowel Syndrome
Status: COMPLETED
Conditions: IBS - Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Normodigest Classic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: G-CSF and PRP in Patients With Recurrent Implantation Failure
Status: UNKNOWN
Conditions: Infertility,Female
Interventions: DRUG: Granulocyte colony-stimulating factor and platelet-rich plasma group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lapatinib Ditosylate and Capecitabine in Treating Patients With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: capecitabine|DRUG: lapatinib ditosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy of Lurasidone in Cognitive Functioning in Bipolar Patients
Status: RECRUITING
Conditions: Bipolar Disorder
Interventions: DRUG: lurasidone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Distal Renal Denervation
Status: COMPLETED
Conditions: Hypertension, Resistant to Conventional Therapy
Interventions: PROCEDURE: Distal renal denervation|PROCEDURE: Conventional renal denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ixazomib and Dexamethasone With or Without Venetoclax in Treating Patients With Non-t(11;14) Relapsed or Refractory Multiple Myeloma
Status: WITHDRAWN
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma|t(11;14) Negative
Interventions: DRUG: Dexamethasone|DRUG: Ixazomib|DRUG: Ixazomib Citrate|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fostering Eating After Stroke With Transcranial Direct Current Stimulation
Status: COMPLETED
Conditions: Dysphagia|Stroke
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Repetitive TMS on Executive Function in Alcohol Use Disorder
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation|DEVICE: Repetitive Transcranial Magnetic Stimulation (Sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Accuracy of a Low-cost, Portable, Autorefractor to Provide Well-tolerated Eyeglass Prescriptions
Status: COMPLETED
Conditions: Refractive Errors
Interventions: OTHER: QuickSee refractive error assessment + glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Application of CO2 Insufflations in Routine Colonoscopy Examination for Duration in Toilet After Examination Compared With Air Insufflations
Status: COMPLETED
Conditions: Carbon Dioxide Insufflation
Interventions: DEVICE: Endoscopic CO2 regulation unit and accessories|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Mechanisms of Neurodynamic Treatments
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome|Neurodynamic Treatment|Nerve Mobilisation|Diffusion MRI|Physiotherapy|Mechanistic Trial
Interventions: OTHER: Neurodynamic exercises|DRUG: Steroid injection (Depomedrone 40mg)|OTHER: Advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Iron Supplementation and Intestinal Health
Status: RECRUITING
Conditions: Anemia of Prematurity|Very Low Birth Weight Infant
Interventions: DRUG: 2mg/kg/day Iron Sulfate|DRUG: 6 mg/kg/day Iron Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Superficial Cervical Plexus Block for Postoperative Analgesia
Status: UNKNOWN
Conditions: Plexus Block;Analgesia;Neurosurgery
Interventions: PROCEDURE: Superficial cervical plexus block|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcome and Biomarkers for Predicting Immunological Response in Patients Treated With Imiquimod
Status: NOT_YET_RECRUITING
Conditions: HSIL, High-Grade Squamous Intraepithelial Lesions|Vaginal Microbiome|Biomarkers
Interventions: DRUG: Imiquimod|PROCEDURE: Loop Electrosurgical Excision Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Leuprolide Acetate for Injectable Suspension 22.5 MG in the Treatment of Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Leuprolide Acetate for Injectable Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Etoricoxib-tramadol Tablet in Acute Postoperative Pain
Status: COMPLETED
Conditions: Acute Pain|Postoperative Pain
Interventions: DRUG: etoricoxib-tramadol|DRUG: Naproxen|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Effect of Individualized Exercise Prescription for Hypertension With 6-minute Walking Test (6MWT)
Status: NOT_YET_RECRUITING
Conditions: Hypertension
Interventions: BEHAVIORAL: CPET exercise prescription|BEHAVIORAL: 6MWT exercise prescription|BEHAVIORAL: Regular exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of BIIL 284 BS on Induced-sputum Variables in Patients With Bronchial Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: BIIL 284 BS|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing Efficacy & Safety of Ribociclib in Patients With Advanced Well/Dedifferentiated Liposarcoma
Status: UNKNOWN
Conditions: Liposarcomas, Dedifferentiated|Liposarcoma - Well Differentiated|Liposarcoma; Mixed Type|Soft-Tissue Sarcoma
Interventions: DRUG: Ribociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stroke Oral healthCare pLan Evaluation
Status: COMPLETED
Conditions: Cerebrovascular Disorders|Stroke|Pneumonia|Oral Hygiene
Interventions: OTHER: Enhanced complex oral health care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Safety and Efficacy Study of Abiraterone Acetate in Participants With Prostate Cancer Who Have Failed Hormone Therapy
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Abiraterone acetate|DRUG: Abiraterone acetate MTD|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin and CBSST for People With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: CBSST + Oxytocin|DRUG: CBSST + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Mirror Therapy Combined With Progressive Strength Training in Unilateral Spastic Cerebral Palsy
Status: COMPLETED
Conditions: Spastic Hemiplegic Cerebral Palsy
Interventions: OTHER: control group|OTHER: intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Rifapentine-Isoniazid Evaluation for TB Prevention (BRIEF TB)
Status: COMPLETED
Conditions: Tuberculosis|HIV Infections
Interventions: DRUG: Rifapentine (RPT)|DRUG: Isoniazid (INH)|DIETARY_SUPPLEMENT: Pyridoxine (Vitamin B6)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Association Among Headache Severity, Head Posture, Cervical Muscle Endurance, and Neck Disorders in Individuals With Migraine
Status: RECRUITING
Conditions: Migraine Disorders
Interventions: OTHER: To assess headache severity, head posture, cervical muscle endurance and neck disorders.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Obatoclax, Fludarabine, and Rituximab in Treating Patients With Previously Treated Chronic Lymphocytic Leukemia
Status: TERMINATED
Conditions: B-cell Chronic Lymphocytic Leukemia|Leukemia|Prolymphocytic Leukemia|Refractory Chronic Lymphocytic Leukemia|Stage I Chronic Lymphocytic Leukemia|Stage II Chronic Lymphocytic Leukemia|Stage III Chronic Lymphocytic Leukemia|Stage IV Chronic Lymphocytic Leukemia
Interventions: DRUG: obatoclax mesylate|DRUG: fludarabine phosphate|BIOLOGICAL: rituximab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylaxis to Reduce Postoperative Atrial Fibrillation in Cardiac Surgery
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DRUG: beta blockers|DRUG: amiodarone|DRUG: ascorbic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Daily HemoDialysis at Low Dialysate Flow in Patients Previously Treated With Conventional Hemodialysis
Status: TERMINATED
Conditions: End Stage Renal Disease
Interventions: OTHER: Daily hemodialysis at low dialysate flow
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dendritic Cells(DC)-Based Id Vaccination in Stage-I Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma|Plasmocytoma
Interventions: BIOLOGICAL: autologous idiotype-protein pulsed dendritic cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetic Study of Fixed Dose Combination of Zidovudine, Lamivudine, and Nevirapine in HIV-Infected Children in Thailand
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: GPO-Vir Z30 tablet|DRUG: Lamivudine|DRUG: Nevirapine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT