pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety of Grazoprevir (MK-5172) and Uprifosbuvir (MK-3682) With Elbasvir (MK-8742) or Ruzasvir (MK-8408) for Chronic Hepatitis C Virus (HCV) Genotype (GT) 3, GT4, GT5, and GT6 Infection (MK-3682-012)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Grazoprevir|DRUG: Uprifosbuvir|DRUG: Elbasvir|DRUG: Ruzasvir|DRUG: MK-3682B|DRUG: Ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Mindfulness Intervention for Endometriosis Surgery
Status: RECRUITING
Conditions: Endometriosis|Pain|Mindfulness
Interventions: BEHAVIORAL: pain education|BEHAVIORAL: mindfulness of pain introduction and intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Activity of Cerebral Networks, Amyloid and Microglia in Aging and Alzheimer's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease|Corticobasal Syndrome
Interventions: DIAGNOSTIC_TEST: magnetic resonance imaging|OTHER: electroencephalography|DIAGNOSTIC_TEST: blood and CSF biomarker|DIAGNOSTIC_TEST: positron emission tomography|DIAGNOSTIC_TEST: neuropsychological test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Modified Cuff Leak Test and Reintubation in Mechanically Ventilated Patients
Status: COMPLETED
Conditions: Mechanical Ventilation Complication|Weaning Failure|Airway Obstruction
Interventions: DIAGNOSTIC_TEST: Cuff Leak Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Global Study to Assess the Drug Dynamics, Efficacy, and Safety of Venglustat (GZ/SAR402671) in Parkinson's Disease Patients Carrying a Glucocerebrosidase (GBA) Gene Mutation
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: DRUG: venglustat GZ/SAR402671|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy Plus Hormone Therapy in Biochemically-relapsing Prostate Cancer Patients Following Surgery
Status: COMPLETED
Conditions: Biochemically-relapsing Prostate Adenocarcinoma Following Radical Prostatectomy
Interventions: DRUG: Abiraterone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacist-Led Intervention to Increase Inhaler Access and Reduce Hospital Readmissions (PILLAR)
Status: ACTIVE_NOT_RECRUITING
Conditions: COPD|Asthma
Interventions: OTHER: Benefits investigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of IMC-1 In Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia|Chronic Pain|Myofascial Pain
Interventions: DRUG: IMC-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SEMA-CardioDiab HUNGARY: A Research Study to Understand the Effects of Oral Semaglutide on Blood Sugar Levels, Weight, and Cardiovascular Risk in People With Type 2 Diabetes Patients in Hungary
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: Oral Semaglutide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Thermal Stimulation for Lower Extremity Movement and Function in Patients With Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: thermal stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of CVVHD With Adsorption Capacity Membranes in Septic Acute Kidney Injury
Status: COMPLETED
Conditions: Sepsis|Septic Shock|Acute Kidney Injury
Interventions: OTHER: CVVHD|OTHER: CVVH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chinese Herbal Medicine in Acute INtracerebral Haemorrhage (CHAIN) Trial
Status: NOT_YET_RECRUITING
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: Chinese herbal medicine FYTF-919
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of the Use of Nandrolone on the Treatment of Malnutrition Induced by Cancer
Status: COMPLETED
Conditions: Cachexia; Cancer
Interventions: DRUG: Nandrolone Decanoate|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: FAPI Molecular Imaging for Diagnosis of the CMS4 Unfavorable Colorectal Cancer Subtype
Status: NOT_YET_RECRUITING
Conditions: Metastatic Colorectal Cancer|Metastatic Cancer to Liver
Interventions: RADIATION: [18F]-ALF-FAPI-74 PET/CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Upper Extremity Manual Lymphatic Drainage on Symptom Severity, Hand Functions, Electrophysiological and Ultrasonographic Measurements in Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: manual lymphatic drainage (MLD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Treatment Effects on OSA-related Clinical and Patient-centered Outcomes Among Blacks
Status: WITHDRAWN
Conditions: Obstructive Sleep Apnea
Interventions: BEHAVIORAL: Tailored Videos|BEHAVIORAL: OSA Treatment|BEHAVIORAL: Standard Videos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Impact of Pycnogenol® on Gingival Inflammation
Status: COMPLETED
Conditions: Periodontitis
Interventions: DIETARY_SUPPLEMENT: Pycnogenol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3, Long-Term Safety Study of Subcutaneous Epoetin Hospira in Patients With Chronic Renal Failure Requiring Hemodialysis and Receiving Epoetin Maintenance Treatment. AiME -Anemia Management With Epoetin
Status: COMPLETED
Conditions: Chronic Renal Failure Requiring Hemodialysis
Interventions: BIOLOGICAL: Epoetin Hospira
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy With NC-6004 and Pembrolizumab in Head and Neck Cancer Subjects Who Have Failed Platinum Regimen
Status: UNKNOWN
Conditions: SCCHN
Interventions: DRUG: NC-6004|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Live Stream of Prehospital point-of Care Ultrasound by Air Rescue Physicians
Status: WITHDRAWN
Conditions: Echocardiography|Telemedicine
Interventions: OTHER: Point-of-care ultrasound with tele-supervision|OTHER: Point-of-care ultrasound without tele-supervision
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Premedication Type(Pharmalogical and Non Pharmalogical) on Delirium
Status: UNKNOWN
Conditions: Emergence Agitation
Interventions: OTHER: Oral midazolam|OTHER: Film http://www.animaturk.com/animasyon/suko-ameliyat-oluyor|OTHER: Play game (PC fishing game)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Evaluation of Liver Disease in Individuals Attending Alcohol Abuse Treatment - a Randomized Controlled Pilot Trial
Status: COMPLETED
Conditions: Liver Diseases
Interventions: DIAGNOSTIC_TEST: Fibroscan|DIAGNOSTIC_TEST: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Oral Olanzapine Versus Haloperidol or Diazepam
Status: TERMINATED
Conditions: Acute Agitation|Behavioural Emergency
Interventions: DRUG: Olanzapine oro-dispersible 5Mg Tab|DRUG: Haloperidol 2Mg encapsulated Tab|DRUG: Diazepam 2Mg encapsulated Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Fish Oil to Reduce Inflammation During Endovascular Abdominal Aortic Repair
Status: COMPLETED
Conditions: PAD|Abdominal Aortic Aneurysm
Interventions: DIETARY_SUPPLEMENT: Pro-Omega|OTHER: ProOmega Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Radial Shockwave on Calf Muscle Spasticity in Patients With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Experimental Interventions|OTHER: Standard physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prediction Using Connected Technologies for Diabetes
Status: COMPLETED
Conditions: Pre-Diabetes
Interventions: DEVICE: Activity Monitoring-Wrist worn wearable|DEVICE: Activity Monitoring-Waist-worn wearable
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ropivacaine/Dexamethasone and 10% Lignocaine Injection in GPN Block for Intractable Cancer Pain
Status: UNKNOWN
Conditions: Cancer, Oropharynx|Pain, Intractable|Cancer Pain
Interventions: PROCEDURE: 0.75 % Ropivacaine/ 4mg/mL dexamethasone injection|PROCEDURE: 10% lignocaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SAR 1118 in Human Subjects Undergoing Pars Plana Vitrectomy
Status: TERMINATED
Conditions: Diabetic Macular Edema (DME)|Pars Plana Vitrectomy
Interventions: DRUG: SAR 1118 0.1%|DRUG: SAR 1118 1.0%|DRUG: SAR 1118 5.0%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Extra Alirocumab in Addition to Statin Therapy in Symptomatic IntraCranial Atherosclerotic Stenosis ----a Pilot Study
Status: RECRUITING
Conditions: Stroke|Intracranial Atherosclerotic Stenosis
Interventions: DRUG: Alirocumab|DRUG: Atorvastatin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Short-term Effects of Oxytocin Nasal Spray on Chronic Tinnitus
Status: COMPLETED
Conditions: Chronic Tinnitus
Interventions: DRUG: Syntocinon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcome Study of Highly-cross Linked Polyethylene vs. Standard Polyethylene for Primary Posterior Stabilized (PS) Total Knee
Status: UNKNOWN
Conditions: Arthroplasty, Replacement, Knee
Interventions: DEVICE: knee arthroplasty, standard polyethylene|DEVICE: knee arthroplasty, XLP polyethylene
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analysis of Health Status of Сomorbid Adult COVID-19 Patients Hospitalised in Second Wave of SARS-CoV-2 Infection
Status: COMPLETED
Conditions: Covid19|Comorbidities and Coexisting Conditions|Risk Factor, Cardiovascular|Death|Diabetes|COPD|Atrial Fibrillation|DVT|CKD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Protecting Our Future Generation: Promotion of Protective Sexual Health Practices Among Native American Youth and Young Adults Through an Assets-based Self-care Intervention
Status: COMPLETED
Conditions: Sexual Behavior|Unprotected Sex|Gonorrhea|Chlamydia|Trichomonas|Sexually Transmitted Diseases|Adolescent Behavior|Self Evaluation
Interventions: BEHAVIORAL: Sexual Health Risk Assessment|BEHAVIORAL: Sexual Health Score|BEHAVIORAL: Sexual Health Messaging|BEHAVIORAL: Water SSB Quiz|BEHAVIORAL: Water SSB Score|BEHAVIORAL: Water SSB Messaging|BEHAVIORAL: STI Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PLATELET RICH FIBRIN COMBINED WITH 1.2% ATORVASTATIN FOR TREATMENT OF INTRABONY DEFECTS IN CHRONIC PERIODONTITIS
Status: COMPLETED
Conditions: Periodontitis
Interventions: DRUG: Platelet rich fibrin +Atorvastatin|DRUG: Platelet rich fibrin|PROCEDURE: open flap debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Statin Therapy for Ischemic and Nonischemic Cardiomyopathy
Status: COMPLETED
Conditions: Cardiovascular Disease|Cardiomyopathy|Heart Disease|Myocardial Disease|Myocardial Ischemia
Interventions: DRUG: Atorvastatin Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SOM230 Alone or in Combination With RAD001 in Patients With Medullary Thyroid Cancer
Status: COMPLETED
Conditions: Medullary Thyroid Cancer
Interventions: DRUG: SOM230 alone or in combination with RAD001.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ischaemic-Reperfusion in Man - A Bradykinin Dependent Pathway
Status: COMPLETED
Conditions: Ischaemic Heart Diseases
Interventions: PROCEDURE: Forearm vascular study|DRUG: bradykinin receptor antagonist (HOE-140)|DRUG: Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acute Effect of Exogenous Ketosis on Sleep Architecture Following Strenuous Exercise
Status: UNKNOWN
Conditions: Sleep
Interventions: DIETARY_SUPPLEMENT: Ketone ester|DIETARY_SUPPLEMENT: Placebo|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rapid Identification of MINOCA Based on Novel Biomarkers
Status: UNKNOWN
Conditions: Myocardial Infarction With Non-obstructive Coronary Arteries|Grow Stimulation Expressed Gene 2|Copeptin|Identification|Prognosis
Interventions: BIOLOGICAL: blood biomarkers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NMDA Modulation in Major Depressive Disorder
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: NMDAE|DRUG: Sertraline|DRUG: Placebo Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Study to Evaluate the Efficacy and Safety of Cinryze® for the Treatment of Acute Antibody-mediated Rejection in Participants With Kidney Transplant
Status: TERMINATED
Conditions: Acute Antibody-Mediated Rejection (AMR)
Interventions: BIOLOGICAL: Cinryze®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness of Infliximab and Changes in Hand and Wrist Magnetic Resonance Imaging (MRI) in Participants With Active Rheumatoid Arthritis (RA) (P08136)
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Infliximab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alterations in Coagulation Factor Levels in Patients With End Stage Liver Disease
Status: NOT_YET_RECRUITING
Conditions: Liver Cirrhosis|Hemophilia|Hemophilia A|Hemophilia B|Liver Transplant Disorder|Liver Failure|Coagulation Factor Deficiency
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study To Evaluate The Safety And Efficacy Of IPX066 In Subjects With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Placebo|DRUG: IPX066 95 mg LD|DRUG: IPX066 145 mg LD|DRUG: IPX066 195 mg LD|DRUG: IPX066 245 mg LD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: JMKX000189 for Moderate to Severe Active Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Lupus Erythematosus, Systemic
Interventions: DRUG: JMKX000189|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ravulizumab Versus Placebo in Adult Participants With Dermatomyositis
Status: TERMINATED
Conditions: Dermatomyositis
Interventions: DRUG: Ravulizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Ascending Dose Study Examining the Safety and Pharmacokinetic Profile of Reconstituted High Density Lipoprotein (CSL112) Administered to Patients
Status: COMPLETED
Conditions: Stable Atherothrombotic Disease
Interventions: BIOLOGICAL: CSL112 (reconstituted high density lipoprotein)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: DiaBetter Together for Young Adults With Type 1 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: DiaBetter Together|BEHAVIORAL: Peer Mentor Delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long-term Outcomes After Hypothermic Oxygenated Machine Perfusion of Donor Livers Using Real-world Data
Status: COMPLETED
Conditions: Organ Preservation|Liver Transplantation|Hypothermic Machine Perfusion
Interventions: DEVICE: Hypothermic oxygenated machine perfusion (any device)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interventional Clinical Trial Comparing Kerecis Omega3 Wound Versus SOC in Diabetic Foot Wounds
Status: COMPLETED
Conditions: Diabetes|Diabetic Foot Ulcer
Interventions: DEVICE: Kerecis Omega3 Wound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-CT Fusion Image-guided Minimally Invasive Interventional Treatment of Lumbosacral Nerve Roots
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: ultrasound-CT fusion imaging|PROCEDURE: pure ultrasound guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Amino Acids to Enhance Anabolism After Home-based Exercise
Status: COMPLETED
Conditions: Amino Acids, Essential|Metabolism|Exercise
Interventions: DIETARY_SUPPLEMENT: Novel essential amino acid supplementation|DIETARY_SUPPLEMENT: Branched-chain amino acid supplementation (BCAA)|DIETARY_SUPPLEMENT: Isocaloric carbohydrate supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, PK, and PD Study of IVRs Releasing TFV and LNG
Status: COMPLETED
Conditions: Anti-Infective Agents|Anti-Retroviral Agents|Contraceptive Usage
Interventions: DRUG: TFV/LNG IVR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Photoprotection Efficacy With Sunscreen Formulas Containing the Cyclic Merocyanine Long-UVA Absorber MCE Under Long-UVA Exposure.
Status: UNKNOWN
Conditions: Sunscreen Sensitivity|Ultraviolet-Induced Change in Normal Skin
Interventions: OTHER: cream cyclic merocyanine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hematopoietic Stem Cell Transplant for Dyskeratosis Congenita or Severe Aplastic Anemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Dyskeratosis Congenita|Aplastic Anemia
Interventions: DRUG: Alemtuzumab|DRUG: Fludarabine|DRUG: Cyclophosphamide|RADIATION: Total Body Irradiation|BIOLOGICAL: Stem Cell Transplant|DRUG: Anti-thymocyte globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hysterectomy - A Regional Intervention Study
Status: RECRUITING
Conditions: Benign Hysterectomy|Postoperative Recovery|Preoperative Planning
Interventions: OTHER: Intiensified structured perioperative information
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Stress Echo Ultrasound Contrast in an Urban Safety Net Hospital to Refine Ischemia Evaluation
Status: COMPLETED
Conditions: Chest Pain|Symptomatic Ischemic Equivalent
Interventions: OTHER: UCA stress echocardiography or myocardial SPECT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of Retreatment With Lutathera® in Patients With New Progression of Intestinal Well-differenciated NET
Status: RECRUITING
Conditions: Neuroendocrine Tumors|Intestinal Well Differentiated Endocrine Tumor|Progressive Disease
Interventions: DRUG: Lutathera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Positron Emission Topographic (PET) Study on Depression Patient With Electroacupuncture
Status: COMPLETED
Conditions: Major Depressive Disorder|Depression
Interventions: DRUG: Fluoxetine|PROCEDURE: DCEAS (Hwato®/ Dongbang®)|PROCEDURE: n-CEA (Strietberger®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Estrogen Replacement and Atherosclerosis Trial ; Primary Outcome Measure is Mean Minimal Coronary Artery Diameter After Avg of 3.2 Yrs.
Status: COMPLETED
Conditions: Heart Disease
Interventions: DRUG: 0.625 mg of conjugated equine estrogen|DRUG: 0.625 mg of conjugated equine estrogen plus 2.5 mg of medroxyprogesterone acetate|DRUG: placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of the Consumption of a Fermented Milk Enriched With Plant Sterols (Spain)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: OTHER: 1- Low fat drinkable fermented dairy product enriched with 1.6g of plant sterol (as free equivalent) per unit|OTHER: 2- Low fat drinkable fermented dairy product enriched with 2.0g of plant sterol (as free equivalent) per unit|OTHER: 3- Low fat drinkable fermented dairy product without plant sterols(control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Modulating Cortical Excitability to Improve Functional Movements in Individuals With Patellofemoral Pain
Status: RECRUITING
Conditions: Patellofemoral Pain Syndrome
Interventions: DEVICE: transcranial direct current stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Insulin Degludec/Liraglutide and Insulin Degludec in Combination With Metformin in Chinese Subjects With Type 2 Diabetes Mellitus Inadequately Controlled With Basal Insulin Therapy and Metformin With or Without One Other Oral Antidiabetic Drug (OAD)
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin degludec/liraglutide|DRUG: Insulin degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SGM-101 in Colorectal Brain Metastases.
Status: RECRUITING
Conditions: Rectal Neoplasms|Rectum Cancer|Colorectal Neoplasms|Brain Metastases|Brain Neoplasms|Brain Diseases|Brain Cancer|Brain Tumor|Intestinal Neoplasms|Gastrointestinal Neoplasms|Gastrointestinal Cancer|Gastrointestinal Disease|Intestinal Disease
Interventions: DRUG: SGM-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of iFS™ for Intrastromal Arcuate Keratotomy (ISAK) Procedures
Status: COMPLETED
Conditions: Refractive Astigmatism
Interventions: DEVICE: iFS™ Femtosecond Laser System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Kinesio Taping on Muscle Activation, Muscle Strength and Performance of Young Football Athletes Jump
Status: UNKNOWN
Conditions: Kinesio Taping
Interventions: PROCEDURE: Kinesio Taping|DEVICE: Kinesio Taping placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Work Hour Reductions, Medical Errors, and Intern Well-Being at Providence St. Vincent Medical Center Intensive Care Unit
Status: COMPLETED
Conditions: Sleep Deprivation|Depression
Interventions: OTHER: Reduced work hour schedule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Scaling up an Evidence-based Intervention for Antiretroviral Therapy for PWID in Vietnam: an Implementation Trial
Status: COMPLETED
Conditions: HIV Infections|Drug Use
Interventions: OTHER: Standard Approach (SA)|OTHER: Tailored Approach (TA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study on Optimal Temperature During Cardiopulmonary Bypass (THERMIC-4)
Status: RECRUITING
Conditions: Ischemic Heart Disease|Valvular Heart Disease|Cardiovascular Diseases|Surgery-Complications
Interventions: PROCEDURE: Hypothermic Cardiopulmonary Bypass|PROCEDURE: Normothermic Cardiopulmonary Bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Posterior Femoral Cutaneous Nerve Block on Postoperative Posterior Lateral Knee Analgesia in Patients With TKA
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: PROCEDURE: Posterior Femoral Cutaneous Nerve Combined With Proximal Sciatic and Saphenous Nerve Block|PROCEDURE: Simple Sciatic and Saphenous Nerve Blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Nurse-led Integrated Care of Complex Patients Facilitated By Telemonitoring: The SMaRT Study
Status: RECRUITING
Conditions: Heart Failure，Congestive|Mental Health (Depression)|Diabetes Mellitus|Chronic Obstructive Pulmonary Disease|Hypertension
Interventions: DEVICE: Medly
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the "ST500 SINGLE- DOSE GEL" in Patients With Symptomatic Long Head of the Biceps Tendon Injury
Status: COMPLETED
Conditions: Long Head of Biceps Rupture
Interventions: DEVICE: ST500 SINGLE-DOSE GEL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Simulated Intrauterine Sound Applied to Preterms
Status: COMPLETED
Conditions: Neonatal Intensive Care|Preterm
Interventions: OTHER: Intrauterine Sound Listening Group 1|OTHER: Intrauterine Sound Listening Group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating Efficacy and Safety of Flumatinib for Chronic Phase Chronic Myeloid Leukemia(CML-CP) Without Optimal Response (Warning,Failure) to Imatinib or Dasatinib
Status: RECRUITING
Conditions: CML-CP; Mutation;Suboptimal Response or Failure in TKI
Interventions: DRUG: Flumatinib|DRUG: Nilotinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of SAVR and TAVR on Patient's Activity and Mobility
Status: SUSPENDED
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: SAPIEN 3|DEVICE: SAPIEN XT|DEVICE: INSPIRIS RESILIA|DEVICE: EDWARDS INTUITY|DEVICE: Carpentier-Edwards PERIMOUNT Magna-Ease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: IRB-HSR# 15084 A Prospective, Unblinded, Controlled Study to Evaluate the Effect of the ITPR in Patients Undergoing OPCAB Surgery
Status: UNKNOWN
Conditions: CABG
Interventions: DEVICE: ITPR|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Long-Term Low-Molecular-Weight Heparin Versus Oral Anticoagulants in Deep Venous Thrombosis
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: tinzaparin|DRUG: acenocoumarol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Graft Patency of QFR-guided Versus Angio-guided Coronary Artery Bypass Grafting
Status: UNKNOWN
Conditions: Coronary Artery Disease|Ischemic Heart Disease
Interventions: PROCEDURE: QFR-guided CABG|PROCEDURE: Angio-guided CABG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Internet-delivered Cognitive-behaviour Therapy for Adolescents With Body Dysmorphic Disorder
Status: COMPLETED
Conditions: Body Dysmorphic Disorders|Dysmorphophobia
Interventions: BEHAVIORAL: Exposure and response prevention (ERP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ziprasidone for the Treatment of Psychosis in Patients Who Had Already Had Benefits From Ziprasidone Treatment in a Previous Study
Status: COMPLETED
Conditions: Pyschotic Disorders
Interventions: DRUG: Ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction of Labor Versus Expectant Management of Large for Gestational Age/Macrosomic Babies at Term. A Multi-center Trial
Status: UNKNOWN
Conditions: Macrosomia|Induction of Labor|Expectant Management|Shoulder Dystocia
Interventions: PROCEDURE: Induction of labor group (Group I)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety Study of AP24534 to Treat Chronic Myelogenous Leukemia (CML) and Other Hematological Malignancies
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia|Hematologic Malignancies
Interventions: DRUG: Ponatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Phase of the Chronicle® Offers Management to Patients With Advanced Signs & Symptoms of Heart Failure Study
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Chronicle Implantable Hemodynamic Monitor (IHM) System, Chronicle Implantable Cardioverter Defibrillator (ICD)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SAFETY-Parent: Online Learning Module to Support Parents of Suicidal Youth
Status: ENROLLING_BY_INVITATION
Conditions: Suicide|Suicide, Attempted|Suicide and Self-harm|Suicide Threat
Interventions: BEHAVIORAL: Safe Alternatives for Teens and Youth - Parent (SAFETY-P)|BEHAVIORAL: Treatment As Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Oral Ivermectin and Permethrin 5% Lotion in Treatment of Pediculosis Capitis
Status: COMPLETED
Conditions: Pediculosis
Interventions: DRUG: Permethrin 5% topical lotion|DRUG: Ivermectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tofacitinib on Coagulation and Platelet Function, and Its Role in Thromboembolic Events
Status: RECRUITING
Conditions: Ulcerative Colitis|Thromboembolism
Interventions: DRUG: Tofacitinib|DRUG: Infliximab Adalimumab y Golimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy With or Without Donor Lymphocyte Infusion in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Multiple Myeloma Undergoing Donor Stem Cell Transplant
Status: TERMINATED
Conditions: Leukemia|Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: autologous tumor cell vaccine|BIOLOGICAL: peripheral blood lymphocyte therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lower Dose Decitabine (DAC)-Primed TC (Carboplatin-Paclitaxel) Regimen in Ovary Cancer
Status: UNKNOWN
Conditions: Primary Malignant Neoplasm of Ovary|FIGO Stages II to IV
Interventions: DRUG: Decitabine (DTC Arm)|DRUG: Paclitaxel and Carboplatin (TC Arm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of wtATTR-CM After Carpal Tunnel Release Surgery
Status: RECRUITING
Conditions: Transthyretin Amyloidosis|Transthyretin Cardiac Amyloidosis|Wild-Type Transthyretin-Related (ATTR)Amyloidosis
Interventions: DIAGNOSTIC_TEST: Tenosynovial biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Assay for SARS-CoV-2 (COVID-19) Antibody Detection Indirectly by Immunofluorescence: SARS-CoV2 IIF Method
Status: UNKNOWN
Conditions: Sars-CoV2
Interventions: DIAGNOSTIC_TEST: Immunfluorescence
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: R-MegaCHOP-ESHAP-BEAM in Patients With High-Risk Aggressive B-Cell Lymphomas
Status: COMPLETED
Conditions: Diffuse Large B-Cell Lymphoma.|Primary Mediastinal B-Cell Lymphoma|Follicular Lymphoma Grade III
Interventions: PROCEDURE: immunotherapy|PROCEDURE: Induction treatment part 1|PROCEDURE: Induction treatment part 2 with PBPC collection|PROCEDURE: Induction treatment part 3|PROCEDURE: Consolidation treatment part 1: HD-chemotherapy with ASCT|RADIATION: Consolidation treatment part 2: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Assess the Effect of Intermittent iNO on the Treatment of NTM Lung Infection in CF and Non-CF Patients
Status: COMPLETED
Conditions: Non-Tuberculous Mycobacterial Pneumonia|Cystic Fibrosis|Mycobacterial Pneumonia|Mycobacterium Abscessus Infection|Mycobacterium Avium Complex
Interventions: DEVICE: LungFit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Connexin Genotypes in Cystic Fibrosis
Status: RECRUITING
Conditions: Cystic Fibrosis|Inflammation
Interventions: DIAGNOSTIC_TEST: Genotyping|DIAGNOSTIC_TEST: Lung function|DIAGNOSTIC_TEST: Microbiology|DIAGNOSTIC_TEST: Blood sample|DIAGNOSTIC_TEST: Induced Sputum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Flow Regulation by Opening the SepTum in Patients With Heart Failure; a Prospective, Randomized, Sham-controlled, Double-blind, Global Multicenter Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction (HFpEF)|Heart Failure With Reduced Ejection Fraction (HFrEF)
Interventions: DEVICE: Atrial Flow Regulator|DEVICE: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate Effect on QT/QTc Interval After Multiple Dose of Celecoxib
Status: COMPLETED
Conditions: Qt Interval, Variation in
Interventions: DRUG: Celecoxib|DRUG: Moxifloxacin|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Suitability of Antibiotic Treatment for CAP
Status: COMPLETED
Conditions: Community Acquired Pneumonia
Interventions: OTHER: Intervention group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pericapsular Nerve Group Block (PENG) for Hip Surgery
Status: WITHDRAWN
Conditions: Hip Arthropathy|Postoperative Pain, Acute|Pain, Postoperative
Interventions: DRUG: Active bupivacaine 0.375% PENG block|DRUG: Placebo normal saline PENG block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short Term Treatment With BI 201335, Peginterferon-alpha 2a and Ribavirin in Hepatitis c Virus Genotype-1 Treatment-naïve Patients (SILEN-C3)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: BI 201335|DRUG: BI 201335|DRUG: Pegylated Interferon-alpha (IFN)|DRUG: Ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Tysabri Treatment on Vaccination Response and Lymphocyte Subsets in Subjects With Relapsing Forms of Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: BG00002 (natalizumab)|BIOLOGICAL: keyhole limpet hemocyanin (KLH)|BIOLOGICAL: tetanus diphtheria toxoid vaccine (Td)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Andosan in Allergic and Asthma Patients
Status: COMPLETED
Conditions: Allergic Asthma|Allergic Rhinoconjunctivitis|Immune Tolerance
Interventions: DIETARY_SUPPLEMENT: Andosan|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: 3 Snip Punctoplasty With and Without Mitomycine C.
Status: COMPLETED
Conditions: Punctal Stenosis
Interventions: PROCEDURE: 3-snip punctoplasty|PROCEDURE: 3-snip punctoplasty and Mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Delphinus SoftVue™ ROC Reader Study (DMT SV RRS3)
Status: COMPLETED
Conditions: Breast Cancer Detection|Dense Breast Parenchyma|Benign Breast Findings|Normal Breast Screening|Abnormal Breast Screening
Interventions: DEVICE: Reading of Automated Breast Ultrasound in conjunction with Screening Mammography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Ciclesonide vs Placebo Administered as Once Daily or Twice Daily in Patients Not Treated With Inhaled Corticosteroid.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Ciclesonide (XRP1526)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neuro-immunological Analysis of Idiopathic Rhinitis Patients and Controls Treated With Capsaicin.
Status: COMPLETED
Conditions: Idiopathic Rhinitis Patients|Healthy Controls
Interventions: DRUG: Capsaicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Foot Intrinsic Muscle Training in Individuals With Diabetic Foot Syndrome
Status: COMPLETED
Conditions: Diabetic Foot
Interventions: OTHER: Control|OTHER: Intrinsic Muscle Training|OTHER: Aerobic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cognitive-Behavioral Therapy for Avoidant/Restrictive Food Intake Disorder: A Treatment Development and Pilot Study
Status: COMPLETED
Conditions: Avoidant/Restrictive Food Intake Disorder (ARFID)
Interventions: BEHAVIORAL: CBT-AR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Characteristics of Brodalumab in Hidradenitis Suppurativa
Status: COMPLETED
Conditions: Hidradenitis Suppurativa|Acne Inversa
Interventions: DRUG: Brodalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: DevRobust Treatment for Mal de Débarquement Syndrome
Status: RECRUITING
Conditions: Mal de Débarquement Syndrome
Interventions: BEHAVIORAL: VOR Readaptation|BEHAVIORAL: VOR Habituation|BEHAVIORAL: Visual Motion Desensitization|BEHAVIORAL: Opposing visual motion stimulus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on the Effects of Bifidobacterium Infantis in Active Celiac Disease
Status: COMPLETED
Conditions: Celiac Disease
Interventions: DIETARY_SUPPLEMENT: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Symptom Control 1-year After Circular Stapler Anopexy or Diathermy Excision for Prolapsed Haemorhoids
Status: COMPLETED
Conditions: Hemorrhoids
Interventions: PROCEDURE: Haemorrhoidectomy a.m. Milligan|PROCEDURE: Stapled anopexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Fat Perception on Satiety From Consumption of Reduced Fat Snacks
Status: COMPLETED
Conditions: Appetitive Behavior|Individual Difference|Food Sensitivity|Food Preferences
Interventions: BEHAVIORAL: Expanded Corn Snack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Preoperative Oral Carbohydrates on Quality of Recovery
Status: COMPLETED
Conditions: Evidence of Cholecystectomy
Interventions: DIETARY_SUPPLEMENT: Allocated to Carbohydrated group|DIETARY_SUPPLEMENT: Allocated to Placebo group|DIETARY_SUPPLEMENT: Allocated to MN NPO group,
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Testing the Effectiveness and Safety of a New Prototype of a Passive Industrial Exoskeleton for Back Support
Status: COMPLETED
Conditions: Prevention of Diseases of the Musculoskeletal System
Interventions: DEVICE: Industrial passive exoskeleton with a specific value of the torque of the spring for supporting the back|OTHER: protocol will be performed without exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study of Efficacy and Safety in Premenopausal Women With Hormone Receptor Positive, HER2-negative Advanced Breast Cancer
Status: COMPLETED
Conditions: Advanced Metastatic Breast Cancer
Interventions: DRUG: Ribociclib|DRUG: Tamoxifen|DRUG: Letrozole|DRUG: Anastrozole|DRUG: Goserelin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Measurement Properties of a 5 Time Repeated Instrumented Timed Up and Go (5iTUG)
Status: COMPLETED
Conditions: Measurement Properties of 5iTUG|Physical Disability|Balance|Cognitive Impairment|Leg Strength|Gait Disorder, Sensorimotor|Activity of Daily Living
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fluticasone Furoate Treatment of Daytime Somnolence and Cognitive Performance in Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Fluticasone furoate Nasal Spray 110 mcg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER