pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study on Pneumoconiosis Treated With Whole-lung Lavage Combined With Mesenchymal Stem Cells
Status: COMPLETED
Conditions: Pneumoconiosis
Interventions: PROCEDURE: large volume whole-lung lavage (WLL)|BIOLOGICAL: clinical grade umbilical cord mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Erector Spinae Plane Block and Penile Block in Hypospadias Surgery
Status: UNKNOWN
Conditions: Postoperative Pain|Analgesia
Interventions: PROCEDURE: The ultrasound-guided Sacral Erector spinae plane block|PROCEDURE: The dorsal penile block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Endoscopic Sleeve Gastroplasty Versus Laparoscopic Sleeve Gastrectomy in Obese Subjects With NASH
Status: UNKNOWN
Conditions: Non-alcoholic Steatohepatitis (NASH)
Interventions: PROCEDURE: Endoscopic Sleeve Gastroplasty (ESG) with OverStitch® system + Lifestyle modifications|PROCEDURE: Laparoscopic Sleeve Gastrectomy (LSG) + Lifestyle modifications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Regulatory T-cells Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-versus-Host-Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Graft Versus Host Disease|Chronic GVHD|Complications of Organ Transplant Stem Cells
Interventions: OTHER: Treg-enriched infusion|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MGD013 in Patients With Unresectable or Metastatic Neoplasms
Status: COMPLETED
Conditions: Advanced Solid Tumors|Hematologic Neoplasms|Ovarian Cancer|HER2-positive Advanced Solid Tumors|Non Small Cell Lung Cancer|Small-cell Lung Cancer|Squamous Cell Carcinoma of Head and Neck|Cholangiocarcinoma|Cervical Cancer|TNBC - Triple-Negative Breast Cancer
Interventions: BIOLOGICAL: tebotelimab 1 mg|BIOLOGICAL: tebotelimab 3 mg|BIOLOGICAL: tebotelimab 10 mg|BIOLOGICAL: tebotelimab 30 mg|BIOLOGICAL: tebotelimab 120 mg|BIOLOGICAL: tebotelimab 300 mg|BIOLOGICAL: tebotelimab 400 mg|BIOLOGICAL: tebotelimab 600 mg|BIOLOGICAL: tebotelimab 800 mg|BIOLOGICAL: tebotelimab 1200 mg|BIOLOGICAL: margetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: How Well do Patients With Traumatic Brain Injury Learn New Material Using Learning Styles in Online Science Classrooms?
Status: UNKNOWN
Conditions: Brain Injuries|Brain Injuries, Traumatic|Injury, Brain, Traumatic|Traumatic Brain Injury|Brain Injury, Chronic
Interventions: BEHAVIORAL: CLSI, MI, CR|BEHAVIORAL: CLSI - Unknown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Evaluation of Osteopathy Treatment Efficacy in Pain Support After Breast Surgery in Oncology
Status: TERMINATED
Conditions: Breast Cancer
Interventions: OTHER: OSTEOPATHY + conventional analgesic treatments|OTHER: Conventional analgesic treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Immunotherapy in Subjects With Advanced HPV Associated Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Cancer|HPV Cancers|Anal Cancer|Oropharyngeal Cancer|Vulvar, Vaginal, Penile, Rectal Cancer
Interventions: BIOLOGICAL: PDS0101|BIOLOGICAL: M7824|BIOLOGICAL: NHS-IL12
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Trial of Herbal Melanin in Gastritis Patients
Status: UNKNOWN
Conditions: Acid Dyspepsia|Gastritis
Interventions: OTHER: Herbal Melanin|DRUG: Nexium|DRUG: Amoxil|DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of IDegAsp (Inclusive Three Explorative Formulations) With Insulin Degludec and Insulin Aspart Separately Injected in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec|DRUG: insulin degludec/insulin aspart 30|DRUG: insulin degludec/insulin aspart 40|DRUG: insulin degludec/insulin aspart 45|DRUG: insulin degludec/insulin aspart 55|DRUG: insulin aspart|DRUG: biphasic insulin aspart 30|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Glucose Monitors to Regulate Glucose Levels in Type 2 Diabetics - (Protocol 3)
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: DEVICE: Continuous Glucose Monitor (CGM)|DEVICE: Activity Tracker|BEHAVIORAL: Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Ustekinumab Followed by Abatacept for the Treatment of Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: Ustekinumab|BIOLOGICAL: Abatacept|DRUG: UST Placebo|DRUG: ABA Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2510924 in Participants With Extensive-Stage Small Cell Lung Carcinoma
Status: COMPLETED
Conditions: Extensive Stage Small Cell Lung Carcinoma
Interventions: DRUG: LY2510924|DRUG: Carboplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The EFFect of hIgh Dose ClopIdogrel treatmENT in Patients With Clopidogrel Resistance
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Gluten-Free Dietary Education and Intraneural Facilitation® Therapy on Quality of Life in People With Diabetic Neuropathy
Status: RECRUITING
Conditions: Diabetic Neuropathy, Distal Symmetric Polyneuropathy (Manifestation)
Interventions: OTHER: Intraneural Facilitation® Therapy (INF® Therapy)|OTHER: INF® Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Results After Intravitreal Bevacizumab Treatment Of Neovascular Age-related Macular Degeneration
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ImmunoPET Targeting Trophoblast Cell-surface Antigen 2 (Trop-2) in Solid Tumors
Status: RECRUITING
Conditions: Tumor|Solid Tumor|Positron-Emission Tomography
Interventions: DIAGNOSTIC_TEST: standard-of-care imaging (18F-FDG, 68Ga-PSMA, or 68Ga-DOTATATE PET/CT), 68Ga-THP-Trop2 VHH PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: High-density Lipoprotein (HDL) Cholesterol in Women Taking Tibolone
Status: COMPLETED
Conditions: HDL Cholesterol
Interventions: DRUG: fenofibrate and tibolone|DRUG: tibolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MEK162 in Noonan Syndrome Hypertrophic Cardiomyopathy
Status: WITHDRAWN
Conditions: Cardiomegaly
Interventions: DRUG: MEK162
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RECELL to Promote Healing Following Carbon Dioxide (CO2) Laser Treatment in Cosmetic Patients
Status: TERMINATED
Conditions: Carbon Dioxide Laser|Photoaging
Interventions: DRUG: ReCell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Efficacy and Safety of Ianalumab in Previously Treated Patients With Warm Autoimmune Hemolytic Anemia
Status: RECRUITING
Conditions: Warm Autoimmune Hemolytic Anemia (wAIHA)
Interventions: BIOLOGICAL: Ianalumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ablation of Clinical Ventricular Tachycardia Versus Addition of Substrate Ablation on the Long Term Success Rate of VT Ablation
Status: COMPLETED
Conditions: Ventricular Tachycardia
Interventions: PROCEDURE: Radiofrequency Catheter Ablation (RFCA)|PROCEDURE: Radiofrequency Catheter Ablation (RFCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Analysis of Biomarkers in Response to Acute Moderate-Intensity Activity
Status: RECRUITING
Conditions: Acute Exercise|Aerobic Exercise|Biomarkers
Interventions: BEHAVIORAL: Elliptical Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dual Trigger for Elective Fertility Preservation
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Ovulation triggering with GnRH-a+rhCG|DRUG: Ovulation triggering with GnRH-a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study to Investigate the Safety and Efficacy of HBV DNA Vaccine
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: GENETIC: a mixed plasmid DNA (HB-110)|DRUG: Adefovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Performance Evaluation Study of Arquer's MCM5 Elisa Test (ADXBLADDER) to Aid in the Monitoring of Recurrence in Non-Muscle Invasive Bladder Cancer
Status: RECRUITING
Conditions: Bladder Cancer
Interventions: DIAGNOSTIC_TEST: ADXBLADDER
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety of and Immune Response to an HIV-1 Vaccine (VRC-HIVDNA016-00-VP) and a Vaccine Booster (VRC-HIVADV014-00-VP) in HIV Uninfected East African Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: VRC-HIVDNA016-00-VP|BIOLOGICAL: VRC-HIVADV014-00-VP|BIOLOGICAL: VRC-DILUENT013-DIL-VP|BIOLOGICAL: VRC-HIVADV014-00-VP placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Dose-finding Study of a Combination of Imatinib and BYL719 in the Treatment of 3rd Line GIST Patients
Status: COMPLETED
Conditions: 3rd Line GIST
Interventions: DRUG: ST571 + BYL719
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Sodium Phenylbutyrate in Pre-symptomatic Infants With Spinal Muscular Atrophy
Status: COMPLETED
Conditions: Spinal Muscular Atrophy
Interventions: DRUG: Sodium phenylbutyrate (NaPB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Hepalatide in Subjects With Chronic Hepatitis B
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Hepalatide 2.1mg|DRUG: Hepalatide 4.2mg|DRUG: Hepalatide 6.3mg|DRUG: placebo 2.1mg|DRUG: placebo 4.2mg|DRUG: placebo 6.3mg|DRUG: Pegylated Interferon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Valganciclovir to Prevent Cytomegalovirus Infection in Patients Following Donor Stem Cell Transplantation
Status: COMPLETED
Conditions: Infection
Interventions: DRUG: ganciclovir|DRUG: valganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of MK0663 and an Approved Drug in the Treatment of Osteoarthritis (0663-076)(COMPLETED)
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: MK0663, etoricoxib|DRUG: Comparator: celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Intermittent Fasting and Caloric Deficit for Weight Loss in Women With Polycystic Ovarian Syndrome
Status: COMPLETED
Conditions: Polycystic Ovarian Syndrome|Weight Loss|Intermittent Fasting
Interventions: BEHAVIORAL: intermittent fasting|BEHAVIORAL: Caloric restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Topical Dexamethasone on Histologic Response of Human Dental Pulp
Status: COMPLETED
Conditions: Vital Pulp Therapy
Interventions: DRUG: Dexamethasone applied on pulp or Dexamethasone did not applied on pulp|PROCEDURE: DPC or MP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of BL-M07D1 in Patients With Locally Advanced or Metastatic HER2 Positive/Low Expression Breast Cancer and Other Solid Tumors
Status: RECRUITING
Conditions: Breast Cancer|Locally Advanced or Metastatic Solid Tumor
Interventions: DRUG: BL-M07D1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pevonedistat and Ibrutinib in Treating Participants With Relapsed or Refractory CLL or Non-Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: B-Cell Prolymphocytic Leukemia|Recurrent Chronic Lymphocytic Leukemia|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Follicular Lymphoma|Recurrent Lymphoplasmacytic Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Non-Hodgkin Lymphoma|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Diffuse Large B-Cell Lymphoma|Refractory Follicular Lymphoma|Refractory Lymphoplasmacytic Lymphoma|Refractory Mantle Cell Lymphoma|Refractory Marginal Zone Lymphoma|Refractory Non-Hodgkin Lymphoma|Refractory Small Lymphocytic Lymphoma|Richter Syndrome
Interventions: DRUG: Ibrutinib|OTHER: Laboratory Biomarker Analysis|DRUG: Pevonedistat|OTHER: Pharmacokinetic Study|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Familial Investigations of Childhood Cancer Predisposition
Status: RECRUITING
Conditions: Acute Leukemia|Adenomatous Polyposis|Adrenocortical Carcinoma|AML|BAP1 Tumor Predisposition Syndrome|Carney Complex|Choroid Plexus Carcinoma|Constitutional Mismatch Repair Deficiency Syndrome|Diamond-Blackfan Anemia|DICER1 Syndrome|Dyskeratosis Congenita|Emberger Syndrome|Familial Acute Myeloid Leukemia|Familial Adenomatous Polyposis|Fanconi Anemia|Familial Cancer|Familial Wilms Tumor|Familial Neuroblastoma|GIST|Hereditary Breast and Ovarian Cancer|Hereditary Paraganglioma-Pheochromocytoma Syndrome|Hodgkin Lymphoma|Juvenile Polyposis|Li-Fraumeni Syndrome|Lynch Syndrome|MDS|Melanoma Syndrome|Multiple Endocrine Neoplasia Type 1|Multiple Endocrine Neoplasia Type 2|Neuroblastoma|Neurofibromatosis Type 1|Neurofibromatosis Type II|Nevoid Basal Cell Carcinoma Syndrome|Non Hodgkin Lymphoma|Noonan Syndrome and Other Rasopathy|Overgrowth Syndromes|Pancreatic Cancer|Peutz-Jeghers Syndrome|Pheochromocytoma/Paraganglioma|PTEN Hamartoma Tumor Syndrome|Retinoblastoma|Rhabdoid Tumor Predisposition Syndrome|Rhabdomyosarcoma|Rothmund-Thomson Syndrome|Tuberous Sclerosis|Von Hippel-Lindau Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Endothelial Dysfunction, Monocyte Activation, and Vasculopathy in Patients With Obstructive Sleep Apnea (OSA) and Effect of 6-month CPAP Treatment
Status: UNKNOWN
Conditions: Sleep Apnea, Obstructive|Continuous Positive Airway Pressure|Endothelium|Inflammation|Vascular Function
Interventions: DEVICE: Therapeutic CPAP|DEVICE: Subtherapeutic CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A MultiCenter Study of Combined PEX, Rituximab, and Steroids in Acute Idiopathic Pulmonary Fibrosis Exacerbations
Status: WITHDRAWN
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Standard Steroid Treatment|DRUG: The Standard Steroid Treatment, Plasma Exchange and rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab Versus Ranibizumab in Age Related Macular Degeneration
Status: UNKNOWN
Conditions: Age Related Macular Degeneration
Interventions: DRUG: Ranibizumab (Intravitreal injection)|DRUG: Bevacizumab (Intravitreal injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of (IDA) by (FPC) Delivered Via Infusion Pump in Patients Receiving Home Infusion Therapy
Status: UNKNOWN
Conditions: Iron Deficiency Anemia
Interventions: DRUG: Triferic AVNU|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1
Status: COMPLETED
Conditions: Neurofibromatosis|MPNST
Interventions: PROCEDURE: MRI, FDG-PET/CT scans|DRUG: [18F]-FLT-PET/CT scans
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multimodal Analgesia With NSAID vs. Narcotics Alone After Shoulder Instability Surgery
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: OTHER: ibuprofen 600 mg|OTHER: Oxycodone/acetaminophen (Percocet) 5 mg/325
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Non-cultured Autologous Keratinocyte Suspension Versus Traditional Split Skin Graft for Burn Wounds Treatment
Status: WITHDRAWN
Conditions: Burn Wound
Interventions: PROCEDURE: Non-cultured keratinocyte suspension|PROCEDURE: Split skin Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Syngery-Evaluating the Impact of Decision Aid
Status: COMPLETED
Conditions: Implantable Cardioverter-defibrillators (ICDs)
Interventions: BEHAVIORAL: Pre-visit timing of receipt of the ICDs implantation decision aid|BEHAVIORAL: Post-visit timing of receipt of the ICDs implantation decision aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: High-Dose Chemotherapy and Autologous Blood Cell Transplantation in Treating Patients With Primary, Locally Advanced, or Stage IV Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Drug/Agent Toxicity by Tissue/Organ
Interventions: DRUG: amifostine trihydrate|DRUG: cyclophosphamide|DRUG: mitoxantrone hydrochloride|DRUG: thiotepa|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Double Endotamponade With Perfluorodecalin and Silicone Oil in Retinal Detachment Surgery.
Status: UNKNOWN
Conditions: Retinal Detachment
Interventions: PROCEDURE: Vitrectomy and tamponade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Linagliptin as Add on Therapy to Empagliflozin 10 mg or 25 mg With Japanese Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: empagliflozin 10 mg + linagliptin 5 mg|DRUG: empagliflozin 10 mg|DRUG: empagliflozin 25 mg + linagliptin 5 mg|DRUG: empagliflozin 25 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rho Kinase Inhibitor in Amyotrophic Lateral Sclerosis (REAL)
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Fasudil (WP-0512)|DRUG: Fasudil (WP-0512)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Semet (80 and 160 mcg) Versus Placebo in Euthyroid Patients With AIT
Status: UNKNOWN
Conditions: Thyroiditis Autoimmune
Interventions: DIETARY_SUPPLEMENT: Selenomethionine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Atacicept in Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Lupus Erythematosus, Systemic
Interventions: DRUG: Atacicept 75 milligram (mg)|DRUG: Atacicept 150 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Pharmacokinetics in the Obese
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A First-In-Human Phase 1 Trial of T-Cell Membrane-Anchored Tumor Targeted Il12 (Attil12)- T-Cell Therapy in Subjects With Advanced/Metastatic Soft Tissue and Bone Sarcoma
Status: RECRUITING
Conditions: Soft Tissue Sarcoma|Bone Sarcoma
Interventions: DRUG: Cyclophosphamide|DRUG: attIL2-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Dezocine Pretreatment on Dexamethasone Induced Perineal Irritation
Status: COMPLETED
Conditions: Adverse Effect
Interventions: DRUG: dezocine|OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Axillary Ultrasound With or Without Sentinel Lymph Node Biopsy in Detecting the Spread of Breast Cancer in Patients Receiving Breast Conservation Therapy
Status: TERMINATED
Conditions: Breast Neoplasms
Interventions: PROCEDURE: Sentinel Lymph Node Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Extended Intravenous of Beta-lactams in the Treatment of Serious Gram-negative Infections in Critically Ill Patients
Status: UNKNOWN
Conditions: Gram-Negative Bacterial Infections
Interventions: DRUG: Beta-Lactams|DRUG: Beta-Lactams
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Posterior Column Spinal Osteotomies in the Treatment of Adolescent Idiopathic Scoliosis
Status: NOT_YET_RECRUITING
Conditions: Adolescent Idiopathic Scoliosis
Interventions: PROCEDURE: Posterior column osteotomy|PROCEDURE: No osteotomies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Safety, Tolerability And Metabolism Of GSK221149A, In Pregnant Women (30-36 Weeks), In Pre-Term Labor
Status: COMPLETED
Conditions: Obstetric Labour, Premature
Interventions: DRUG: GSK221149A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rifaximin Plus Lactulose Versus Lactulose Alone for the Treatment of Hepatic Encephalopathy: a Double Blind Randomized Trial
Status: COMPLETED
Conditions: Hepatic Encephalopathy
Interventions: DRUG: Rifaximin plus lactulose|DRUG: Lactulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trofosfamide Versus Adriamycin in Elderly Patients With Soft Tissue Sarcoma (STS)
Status: UNKNOWN
Conditions: Sarcoma, Soft Tissue
Interventions: DRUG: Adriamycin|DRUG: Trofosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Fruquintinib Combined With Sintilimab and XELOX Regimen in the Treatment of Advanced Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Fruquintinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Orelabrutinib Combined With Obinutuzumab and Lenalidomide (OGL Regimen) as First-line Treatment for Marginal Zone Lymphoma.
Status: RECRUITING
Conditions: Marginal Zone Lymphoma
Interventions: DRUG: Orelabrutinib, obinutuzumab, lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Hippotherapy and Schroth Exercise on Pulmonary Function and Aerobic Capacity in Idiopathic Scoliosis
Status: COMPLETED
Conditions: Scoliosis Idiopathic
Interventions: OTHER: hippotherapy and schroth exercise|OTHER: schroth exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tumor Necrosis Factor Inhibition in Focal Segmental Glomerulosclerosis and Treatment Resistant Minimal Change Disease
Status: COMPLETED
Conditions: FSGS|MCD|Focal Segmental Glomerulosclerosis|Minimal Change Disease
Interventions: DRUG: adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vitamin D Can Increase Pathological Response of the Breast Cancer Patients Treated With Neoadjuvant Therapy
Status: COMPLETED
Conditions: Vitamin D Deficiency|Chemotherapy Effect|Pathology
Interventions: DRUG: Vit D
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Trial of Neoadjuvant Radiosurgery for the Treatment of Metastatic Brain Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain Metastases
Interventions: RADIATION: Neoadjuvant stereotactic radiosurgery|PROCEDURE: Neurosurgical resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Once-daily Antiretroviral Therapy in HIV-1 Infected Patients With CD4+ Cell Counts Below 100 Cells/Mcl
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: tenofovir + emtricitabine + efavirenz|DRUG: tenofovir + emtricitabine + lopinavir-ritonavir|DRUG: tenofovir + emtricitabine + atazanavir-ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TF-CBT for Long-term PTSD, Major Depressive Disorder and Anxiety Disorders in Victims of Terrorism
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Major Depressive Disorder|Anxiety Disorders
Interventions: BEHAVIORAL: TF-CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human Serum Albumin/Granulocyte Colony Stimulating Factor Fusion Protein for Breast Cancer Patients
Status: COMPLETED
Conditions: Chemotherapy-induced Neutropenia
Interventions: DRUG: rHSA-GCSF 2.4mg|DRUG: GCSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of 4975 in Patients Undergoing Arthroscopic Surgery to Repair the Rotator Cuff of the Shoulder
Status: TERMINATED
Conditions: Rotator Cuff Repair of the Shoulder
Interventions: DRUG: 4975 - Highly purified capsaicin|DRUG: 4975 - Highly purified capsaicin|DRUG: 4975 - Highly purified capsaicin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acceptability and Feasibility of a Universal Preventive Intervention
Status: NOT_YET_RECRUITING
Conditions: Depression/Anxiety
Interventions: BEHAVIORAL: "Universal preventive intervention for depression and anxiety for university students"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant ChemoRadiotherapy Followed by Immunotherapy and Surgery for Resectable Esophageal Squamous Cell Carcinoma（CRIS-2 Trial）
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: RADIATION: Neoadjuvant chemoradiotherapy followed by immunotherapy|DRUG: Neoadjuvant chemoimmunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BGT007 Cell Treatment of Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: BIOLOGICAL: BGT007 Cell Injection|DRUG: Fludarabine|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visualization Versus Intraoperative Neuromonitoring of the Recurrent Laryngeal Nerves During Thoracoscopic Esophagectomy
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: PROCEDURE: intraoperative nerve monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Lemborexant in Chinese Participants With Insomnia Disorder
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: DRUG: Lemborexant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Infraorbital and Infratrochlear Nerve Block on Emergence Agitation in Patients Undergoing Septorhinoplasty
Status: UNKNOWN
Conditions: Emergence Agitation|Pain
Interventions: DRUG: Normal Saline|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Proof-of-Mechanism Study to Determine the Effect of Danicopan on C3 Levels in Participants With C3G or IC-MPGN
Status: COMPLETED
Conditions: C3 Glomerulonephritis|Dense Deposit Disease|C3 Glomerulopathy|Immune Complex Mediated Membranoproliferative Glomerulonephritis|Membranoproliferative Glomerulonephritis Types I, II, and III
Interventions: DRUG: Danicopan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Can Tranexamic Acid Reduce Bleeding After Post Partum Hemorrhage in Cesarean Section Delivery
Status: COMPLETED
Conditions: Post Partum Hemorrhage
Interventions: DRUG: Tranexamic Acid|DRUG: saline serum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating The Quality of Recovery After Elective Cesarean Section
Status: COMPLETED
Conditions: Quality of Recovery|Elective Cesarean Section|Quadratus Lumborum Block|Patient Controlled Analgesia
Interventions: PROCEDURE: QL block|DRUG: PCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Maxera Large Cups - Canada
Status: TERMINATED
Conditions: Degenerative Joint Disease of Hip|Osteoarthritis, Hip|Avascular Necrosis of Hip|Post-Traumatic Osteoarthritis of Hip|Congenital Dysplasia of the Hip|Joint Diseases|Rheumatoid Arthritis of Hip
Interventions: DEVICE: Total hip arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety and Efficacy Study of Anti-inflammatory (Canakinumab) and Cartilage Stimulating (LNA043) Drugs Injected Into the Knee Joint of Participants With Knee Osteoarthritis (OA)
Status: TERMINATED
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: canakinumab|BIOLOGICAL: LNA043|OTHER: Placebo to canakinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Drug Interaction Study of Lanabecestat (LY3314814) and Warfarin in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lanabecestat|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treating Primary Sclerosing Cholangitis and Biliary Atresia With Vancomycin
Status: RECRUITING
Conditions: Primary Sclerosing Cholangitis|Biliary Atresia
Interventions: DRUG: Oral Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Letrozole /GnRH Antagonist Protocol in Women Over 40 Years Undergoing ICSI Cycle
Status: UNKNOWN
Conditions: Ovarian Stimulation
Interventions: DRUG: Letrozole 2.5mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Acute Kidney Injury by N-Acetylcystein in Patients Undergone Cardiac Valve Replacement
Status: UNKNOWN
Conditions: Surgery--Complications|Cardiac Valve Disease|Acute Kidney Injury|Oxygen Radical Damage|Post-Op Complication
Interventions: DRUG: N Acetyl Cysteine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cardiac Implantable Electronic Device remOval Versus Full coUrse Medical Treatment
Status: NOT_YET_RECRUITING
Conditions: Cardiac Implantable Electronic Device Infection
Interventions: PROCEDURE: Cardiac implantable electronic device extraction|DRUG: Empirical antibiotic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Myelodysplastic Syndrome (MDS) With Cytokine-Immunotherapy for Low-Risk MDS
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: Erythropoietin|DRUG: Cyclosporin A|DRUG: G-CSF|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Childhood Onset Psychiatric Disorders With Intravenous Immunoglobulin (IVIg)
Status: COMPLETED
Conditions: Autoimmune Diseases|Mental Disorders Diagnosed in Childhood|Schizophrenia
Interventions: DRUG: Intravenous immunoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: CT Detection of Metastatic Lymphadenopathy in Papillary Thyroid Cancer
Status: COMPLETED
Conditions: Papillary Thyroid Cancer
Interventions: DIAGNOSTIC_TEST: Use of IV contrast during head and neck CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Sirolimus Versus Sirolimus Plus Prednisolone for Kaposiform Hemangioendothelioma
Status: COMPLETED
Conditions: Kaposiform Hemangioendothelioma|Kasabach Merritt Phenomenon
Interventions: DRUG: Sirolimus|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cabozantinib-S-Malate in Treating Patients With Hormone-Resistant Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Hormone-resistant Prostate Cancer|Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: cabozantinib-s-malate|RADIATION: fluorine F 18 d-FMAU|PROCEDURE: positron emission tomography|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Dopaminergic Asymmetric Degeneration and Attentional Resources in Parkinson's Disease.
Status: COMPLETED
Conditions: Parkinson Disease|Attention Disturbances
Interventions: OTHER: MIRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Clinical Study to Assess Safety and Efficacy of a Tumor Vaccine in Patients With Advanced Renal Cell Carcinoma (ASET)
Status: COMPLETED
Conditions: Stage IV Renal Cell Cancer
Interventions: BIOLOGICAL: MGN1601
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROStep: A Feasibility Trial Using PROs and Step Data to Monitor Patients With Lung and GI Cancers
Status: COMPLETED
Conditions: Cancer|Lung Cancer|Gastro-intestinal
Interventions: OTHER: PRO questionnaire|OTHER: Step monitoring|OTHER: Active nudge text feedback|OTHER: PROStep Dashboard (clinicians)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Pharmacokinetic Study of Dapivirine Vaginal Rings in Belgium
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: dapivirine reservoir intravaginal ring|DRUG: dapivirine matrix intravaginal ring|OTHER: placebo intravaginal ring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Monthly Boluses Versus Daily Doses for Correcting Blood Vitamin D Deficit in Obese Children and Adolescents
Status: NOT_YET_RECRUITING
Conditions: Obesity, Childhood
Interventions: DRUG: Monthly bolus of cholecalciferol per os|DRUG: Daily dose of cholecalciferol per os|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Telerehabilitation-Based Pelvic Floor Muscle Training in People With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Urinary Incontinence
Interventions: BEHAVIORAL: Telerehabilitation-based pelvic floor muscle training|BEHAVIORAL: Home-based pelvic floor muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting Non-virally Suppressed Adults With Alcohol Use Disorder in HIV Primary Care
Status: TERMINATED
Conditions: Alcohol Dependence|HIV/AIDS
Interventions: BEHAVIORAL: Clinician Guide (CG)|BEHAVIORAL: Clinician Guide plus HealthCall
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Structured Exercise Training Program Plus Diet Intervention in Patients With Polycystic Ovary Syndrome (PCOS)
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Anovulation
Interventions: OTHER: SET-diet plus clomiphene|DRUG: Clomiphene citrate|BEHAVIORAL: Structured exercise program plus hypocaloric diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leukotriene D4 Bronchial Provocation Test (LTD4-BPT) as an Indicator for the Use of Leukotriene Receptor Antagonist (LTRA)
Status: COMPLETED
Conditions: Bronchial Asthma
Interventions: DRUG: leukotriene receptor antagonist (montelukast)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Transcoronary Infusion of Cardiac Progenitor Cells in Pediatric Dilated Cardiomyopathy
Status: COMPLETED
Conditions: Dilated Cardiomyopathy
Interventions: BIOLOGICAL: CDC infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HMPL-760 in Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma
Status: RECRUITING
Conditions: B-Cell Non-Hodgkin's Lymphoma
Interventions: DRUG: HMPL-760
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance Assessment of a Modified Daily Disposable Contact Lens
Status: COMPLETED
Conditions: Refractive Errors|Myopia|Hyperopia
Interventions: DEVICE: Modified delefilcon A contact lenses|DEVICE: Delefilcon A contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiome Transplantation (FMT) in Pediatric Patients Colonized With Antibiotic-resistant Pathogens Before Hematopoietic Stem Cell Transplantation (HSCT)
Status: UNKNOWN
Conditions: Antibiotic Resistant Strain
Interventions: OTHER: FMT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Opioid Treatment and Peer Recovery Support
Status: RECRUITING
Conditions: Opioid-use Disorder
Interventions: BEHAVIORAL: Core Intervention|BEHAVIORAL: Peer Support Specialists (PSS)|BEHAVIORAL: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Development of a Multi-faceted Cognitive Training Program for Children With Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: OTHER: Multifaceted cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Randomized Clinical Trail Evaluate Effectiveness and Security of Capecitabine or Endocrinotherapy as a Maintenance Therapy Regimen After the 1st-line Chemotherapy With Capecitabine Combine Regimen in Hormone Receptor Positive and HER2 Negative Metastatic Breast Cancer(Overstep)
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Capecitabine|PROCEDURE: endocrine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Community Health Worker Strategy on Produce Prescription Program Uptake Among People With Diabetes
Status: NOT_YET_RECRUITING
Conditions: Diabetes Type 2
Interventions: BEHAVIORAL: Community health worker (CHW) strategy|BEHAVIORAL: PRx Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison Between FDG-PET and MRI for the Assessment of Response to Intensive Chemotherapy in Multiple Myeloma Patients.
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: FDG = fluorodeoxyglucose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: AGNOSTIC THERAPY IN A PHASE II SINGLE-ARM STUDY IN FIRST-LINE TREATMENT OF DURVALUMAB IN ASSOCIATION WITH CARBOPLATIN OR CISPLATIN AND ETOPOSIDE IN PATIENTS AFFECTED BY EXTENSIVE STAGE - EXTRAPULMONARY SMALL CELL CARCINOMA
Status: RECRUITING
Conditions: Extrapulmonary Small Cell Carcinoma
Interventions: DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gut Hormones After Oral Versus Intravenous Amino Acids
Status: COMPLETED
Conditions: Normal Non-fluency
Interventions: OTHER: Oral amino acid mixture|OTHER: Intravenous amino acid administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Bioequivalence Study of Sildenafil Citrate Orally-Disintegrating Film Dosage Form
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: Viagra Tablet|DRUG: Sildenafil Citrate ODF|DRUG: Sildenafil Citrate ODF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnesium Chloride Versus Placebo in Patients Who Have Had a Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Magnesium Chloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial in Subjects Undergoing Cardiac Catheterization With Planned Percutaneous Coronary Intervention With Stenting
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Prasugrel|DRUG: Clopidogrel|DRUG: Placebo for Prasugrel|DRUG: Placebo for Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT