pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: 89Zr-MMOT PET Imaging in Pancreatic and Ovarian Cancer Patients
Status: COMPLETED
Conditions: Ovarian Neoplasms|Ovarian Diseases|Adnexal Diseases|Pancreatic Neoplasms|Digestive System Neoplasms|Digestive System Diseases|Pancreatic Diseases
Interventions: DRUG: 89Zr-MMOT0530A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Optical Surface Monitoring Technology-Guided Large-Segment Radiotherapy for Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Optical Surface Monitoring Technology|Large-segment Radiotherapy
Interventions: DEVICE: Surface Guided Radiation Therapy (SGRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Modulation by Parenteral Lipids
Status: COMPLETED
Conditions: Infections|Total Parenteral Nutrition
Interventions: DIETARY_SUPPLEMENT: Parenteral lipid emulsion (Omegaven)|DIETARY_SUPPLEMENT: Parenteral lipid emulsion (Intralipid)|DIETARY_SUPPLEMENT: Parental lipid emulsion (Saline 0.9%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: T-Lymphocytes for Prevention or Treatment of Viral Infections Following Hematopoietic Stem Cell Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Viral Infections|Bone Marrow Transplant Infection
Interventions: BIOLOGICAL: Virus Specific T cells (VSTs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regorafenib Assessment in Refractory Advanced Colorectal Cancer(RegARd-C)
Status: COMPLETED
Conditions: Advanced Chemorefractory Colorectal Adenocarcinoma
Interventions: DRUG: regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cervical Mobility on Cardiovascular And Respiratory Outcomes Among Young Adults
Status: UNKNOWN
Conditions: Neck Pain|Blood Pressure
Interventions: OTHER: Traction Mobilization technique|OTHER: Traction Mobilization technique with SNAGS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Adherence Therapy for Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizophreniform Disorder|Schizoaffective Disorder
Interventions: BEHAVIORAL: Adherence therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Trial of Low Dose Sulindac Combined With Eflornithine in Patients With Familial Adenomatous Polyposis (FAP)
Status: WITHDRAWN
Conditions: Familial Adenomatous Polyposis
Interventions: DRUG: Eflornithine plus Sulindac|DRUG: Eflornithine plus Placebo|DRUG: Sulindac plus Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity on Postural Stability and Coordination in Children With Posterior Fossa Tumor
Status: COMPLETED
Conditions: Posterior Fossa Tumor|Medulloblastoma, Childhood
Interventions: BEHAVIORAL: Pilates Core Stability Exercises program|BEHAVIORAL: Balance Program|BEHAVIORAL: Coordination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Tolerability of MBF-118 in Healthy Volunteers
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: MBF-118 oral capsules|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Absorption Profiles of Three Polyphenol Preparations With and Without Pollen Shell Covering
Status: COMPLETED
Conditions: Polyphenols Absorption Profile
Interventions: DIETARY_SUPPLEMENT: Polyphenol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Colonoscopic Probiotics Spray in Irritable Bowel Syndrome
Status: NOT_YET_RECRUITING
Conditions: Effect of Drug
Interventions: BIOLOGICAL: Colonscopic probiotics spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ASXL-Related Disorders Registry
Status: RECRUITING
Conditions: Bohring-Opitz Syndrome|ASXL1 Gene Mutation|Shashi-Pena Syndrome|ASXL2 Gene Mutation|Bainbridge-Ropers Syndrome|ASXL3 Gene Mutation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Controlled Trial of Mecobalamin Injection and Tablet Treatment Efficacy on Mild to Moderate Diabetic Peripheral Neuropathy
Status: UNKNOWN
Conditions: Diabetic Neuropathies
Interventions: DRUG: methylcobalamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Roll of Balance Confidence in Gait Rehabilitation in Persons With a Lesion of the Central Nervous System
Status: RECRUITING
Conditions: Stroke|Spinal Cord Injuries|Traumatic Brain Injury
Interventions: OTHER: Dynamic balance training|OTHER: Traditional gait rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive 3D Mapping for Identifying Origin and Preferential Propagation of Ventricular Arrhythmias
Status: COMPLETED
Conditions: Premature Ventricular Complex|Ventricular Arrythmia
Interventions: DIAGNOSTIC_TEST: Non Invasive Electroanatomical Mapping
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Using Virtual Reality Simulation to Prepare Children Undergoing MRI
Status: COMPLETED
Conditions: Anxiety|Distress
Interventions: BEHAVIORAL: Child Life-led preparation|BEHAVIORAL: MRI preparation video|BEHAVIORAL: KindVR Virtual Reality MRI Preparation Experience
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Combination of PECS II Block and Parasternal Block for Radical Mastectomy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: PECS II and parasternal block|DRUG: Levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Abdominal Colpopexy: Comparison of Endoscopic Surgical Strategies
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Robotic assisted laparoscopic abdominal sacrocolpopexy|PROCEDURE: Standard laparoscopic abdominal sacrocolpopexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect Of Scaling and Root Planning on ALP in Saliva and GCF In Periodontitis Patients Compared With Healthy Individuals
Status: RECRUITING
Conditions: Periodontitis|Healthy
Interventions: DIAGNOSTIC_TEST: Scaling and Root Planning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Administration Strategies of Ticagrelor in Patients With Unstable Angina Pectoris, a Pharmacokinetic / Pharmacodynamic Study
Status: COMPLETED
Conditions: Unstable Angina Pectoris
Interventions: DRUG: Pulverized ticagrelor sublingually|DRUG: Pulverized ticagrelor orally|DRUG: Integral ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Renal Physiology by Magnetic Resonance Imaging (MRI) in Normal Volunteers
Status: COMPLETED
Conditions: Glomerular Filtration Rate|Renal Blood Flow
Interventions: PROCEDURE: Inulin and PAH clearance and MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Omacor and Placebo in Carotid Plaque Stability
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: Omega-3-acid ethyl ester 90 (n-3 PUFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Pharmacokinetics of CC-122 in Subjects With Mild, Moderate, and Severe Renal Impairment
Status: COMPLETED
Conditions: Renal Insufficiency
Interventions: DRUG: CC-122
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Exosomes for the Treatment of Acute Respiratory Distress Syndrome or Novel Coronavirus Pneumonia Caused by COVID-19
Status: NOT_YET_RECRUITING
Conditions: Covid19|Novel Coronavirus Pneumonia|Acute Respiratory Distress Syndrome
Interventions: DRUG: MSC-exosomes delivered intravenously every other day on an escalating dose: (2:4:8)|DRUG: MSC-exosomes delivered intravenously every other day on an escalating dose (8:4:8)|DRUG: MSC-exosomes delivered intravenously every other day (8:8:8)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult T Acute Lymphoblastic Leukemia|Ann Arbor Stage II Adult Lymphoblastic Lymphoma|Ann Arbor Stage II Childhood Lymphoblastic Lymphoma|Ann Arbor Stage III Adult Lymphoblastic Lymphoma|Ann Arbor Stage III Childhood Lymphoblastic Lymphoma|Ann Arbor Stage IV Adult Lymphoblastic Lymphoma|Ann Arbor Stage IV Childhood Lymphoblastic Lymphoma|Childhood T Acute Lymphoblastic Leukemia
Interventions: DRUG: Bortezomib|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Daunorubicin|DRUG: Daunorubicin Hydrochloride|DRUG: Dexamethasone|DRUG: Doxorubicin|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide|DRUG: Hydrocortisone Sodium Succinate|DRUG: Ifosfamide|DRUG: Leucovorin Calcium|DRUG: Mercaptopurine|DRUG: Methotrexate|DRUG: Pegaspargase|RADIATION: Radiation Therapy|DRUG: Thioguanine|DRUG: Vincristine|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: (VELA) Study of BLU-222 in Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors|HR+ Breast Cancer|CCNE1 Amplification|HER2-negative Breast Cancer|Ovarian Cancer|Endometrial Cancer|Gastric Cancer|Esophageal Adenocarcinoma|Carcinosarcoma
Interventions: DRUG: BLU-222|DRUG: Carboplatin|DRUG: Ribociclib|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Head-Cancelled Virtual Reality for Ocular Cranial Nerve Palsies
Status: RECRUITING
Conditions: Internuclear Ophthalmoplegia|Palsy, Abducens
Interventions: BEHAVIORAL: Head-cancelled virtual reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture Research on Lung Cancer Patients With Cancer Related Fatigue（CRF）
Status: UNKNOWN
Conditions: Lung Cancer|Cancer Related Fatigue
Interventions: DEVICE: acupuncture|DEVICE: sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Low Level Laser Therapy on Root Resorption During Orthodontic Intrusion of Maxillary Incisors
Status: ENROLLING_BY_INVITATION
Conditions: Root Resorption of Maxillary Incisors
Interventions: DEVICE: gallium aluminum arsenide (Ga-Al-As) semiconductor diode laser (SMARTTM PRO, LASOTRONIX, Poland)|OTHER: group B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Preliminary Efficacy of PalinGen Flow Amniotic Tissue Allograft in Chronic Ulcers of the Lower Extremities
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Ulcer of Lower Extremity
Interventions: BIOLOGICAL: PalinGen Flow Amniotic Tissue Allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subjective Evaluation of a Commercially Marketed Contact Lens Amongst a Subset of the Contact Lens Wearing Population
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Lotrafilcon B contact lens|DEVICE: Habitual contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of BETAXON 0.5% and AZOPT 1.0% in Pediatric Patients With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: BETAXON (levobetaxolol HCl)|DRUG: AZOPT (brinzolamide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Accuracy of New Diagnostic Technology to Guide Rapid Antibiotic Treatment for Serious Infections
Status: COMPLETED
Conditions: INFECTIONS|Skin and Subcutaneous Tissue Bacterial Infections|Healthcare-associated Infection|Infection Due to Resistant Bacteria
Interventions: DEVICE: Testing on new technology called Accelerate ID/AST system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A CCafU-UroCCR Randomized Trial: 3D Image-Guided Robot-AssisTEd Partial Nephrectomy for Renal Complex Tumor (UroCCR N°99)
Status: NOT_YET_RECRUITING
Conditions: Renal Tumor|Renal Cancer
Interventions: PROCEDURE: Robot assisted partial nephrectomy with 3D image guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Prucalopride in Combination With Polyethylene Glycol or Lactulose in Women With Chronic Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Prucalopride|DRUG: Polyethylene glycol (PEG)|DRUG: Lactulose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BENEFIT: Evaluation of the Use of Antiparasital Drug (Benznidazole) in the Treatment of Chronic Chagas' Disease
Status: COMPLETED
Conditions: Chagas Disease|Trypanosomiasis|Heart Disease
Interventions: DRUG: Benznidazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Transcranial Direct Current Stimulation for Severe Primary Dysmenorrhea
Status: COMPLETED
Conditions: Primary Dysmenorrhea
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Hesperidin on Bone Biomarkers in Postmenopausal Women
Status: COMPLETED
Conditions: Osteopenia|Osteoporosis
Interventions: OTHER: Hesperidin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Botensilimab, Balstilimab and Regorafenib for the Treatment of Patients With Microsatellite Stable Metastatic Colorectal Cancer Who Have Progressed on Prior Chemotherapy
Status: RECRUITING
Conditions: Advanced Colorectal Adenocarcinoma|Advanced Microsatellite Stable Colorectal Carcinoma|Metastatic Colorectal Adenocarcinoma|Metastatic Microsatellite Stable Colorectal Carcinoma|Stage III Colorectal Cancer AJCC v8|Stage IV Colorectal Cancer AJCC v8
Interventions: BIOLOGICAL: Balstilimab|PROCEDURE: Biospecimen Collection|BIOLOGICAL: Botensilimab|PROCEDURE: Computed Tomography|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin Plus Docetaxel With Day 2 Pegylated G-CSF (Neulasta®) in Patients With Advanced Stage Ovarian Carcinoma
Status: TERMINATED
Conditions: Ovarian Cancer
Interventions: DRUG: Docetaxel|DRUG: Carboplatin|DRUG: Pegylated G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Mobile Phone Short Message Service (SMS) Reminder and Consultation on Asthma Control
Status: UNKNOWN
Conditions: Asthma
Interventions: BEHAVIORAL: SMS reminder|OTHER: SMS consultation|OTHER: regular care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of The Impact Of Inlyta In 2nd Line On The Treatment Outcomes Of mRCC Patients Treated With Sutent In 1st Line In The Real Life Setting
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma (mRCC)
Interventions: OTHER: observational
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PT003 MDI Dose Confirmation Study
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: PT003|DRUG: PT001|DRUG: PT005
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Terlipressin on Blood Loss and Transfusion Requirements During Major Liver Resection.
Status: COMPLETED
Conditions: Hepatectomy, Surgical Blood Loss, Terlipressin
Interventions: DRUG: Terlipressin|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of NiTi Shape Memory End-to-End Compression Anastomosis Ring (CAR) for Compression Anastomosis in Anterior Resection
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DEVICE: Compression Anastomosis Ring (CAR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maastricht Investigation of Renal Function in Absence of- and Post- Contrast in Patients With eGFR LEss Than 30
Status: WITHDRAWN
Conditions: Acute Kidney Injury (Nontraumatic)|Contrast-induced Nephropathy|Renal Insufficiency
Interventions: DIAGNOSTIC_TEST: serum creatinine assay
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Neoadjuvant Chemoradiotherapy With 5-FU/Leucovorin (FL) vs. TS-1/Irinotecan in Patients With Locally Advanced Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DRUG: 5-FU with leucovorin|DRUG: TS-1 with Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Building Resilience In Caregivers of Trauma Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Caregiver Burnout
Interventions: BEHAVIORAL: Support as usual|BEHAVIORAL: Problem solving therapy|BEHAVIORAL: ICU diary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Manual Lymphatic Drainage and Transcutaneous Electrical Nerve Stimulation in Premenstrual Syndrome
Status: ENROLLING_BY_INVITATION
Conditions: Premenstrual Syndrome
Interventions: OTHER: Manual Lymphatic Drainage|DEVICE: Transcutaneous Electrical Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S1505: Combination Chemotherapy or Gemcitabine Hydrochloride and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma|Resectable Pancreatic Carcinoma
Interventions: DRUG: Fluorouracil|DRUG: Gemcitabine Hydrochloride|DRUG: Irinotecan Hydrochloride|DRUG: Oxaliplatin|DRUG: Paclitaxel Albumin-Stabilized Nanoparticle Formulation|PROCEDURE: Pancreatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glycemic Characterization and Pancreatic Imaging Correlates in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Cystic Fibrosis-related Diabetes|Cystic Fibrosis Liver Disease|Pancreatic Steatosis|Hepatic Steatosis
Interventions: DEVICE: Frequently Sampled Oral Glucose Tolerance Test and CGM|RADIATION: MRI Pancreas and Liver
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transcutaneous Electroacupuncture for Gastric Complications of Scleroderma
Status: COMPLETED
Conditions: Scleroderma|Gastroparesis
Interventions: DEVICE: transcutaneous electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2 Study of Ensartinib and Durvalumab, in ALK-rearranged Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Carcinoma|NSCLC
Interventions: DRUG: Ensartinib|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SWitching to Abilify Trial (SWAT)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole, Solian, Olanzapine, Seroquel, Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Effects of Plant Sterol and Stanol Esters
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: stanol ester|DIETARY_SUPPLEMENT: sterol ester|DIETARY_SUPPLEMENT: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Temozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid Tumors
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: irinotecan hydrochloride|DRUG: temozolomide|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shigella Sonnei 53G Human Infection Study in Kenyan Adults
Status: NOT_YET_RECRUITING
Conditions: Shigellosis
Interventions: BIOLOGICAL: Shigella sonnei 53G|DRUG: Ciprofloxacin 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact of Low Pressure Pneumo in RARP
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Amount of Pneumoperitoneum Pressure applied during RARP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Baclofen/Diazepam Supps for Treatment of Pelvic Floor Myalgia
Status: UNKNOWN
Conditions: Pelvic Floor Dyssynergia
Interventions: DRUG: Baclofen/diazepam|DRUG: Vaginal placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cold Induced Futile Cycles In White Adipose Tissue
Status: COMPLETED
Conditions: Metabolism Disorder
Interventions: OTHER: External cooling|DIAGNOSTIC_TEST: FDG PET/CT|DIAGNOSTIC_TEST: 13C-Glucose injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety of MT-401-OTS in Patients With Relapsed AML or MDS
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia, in Relapse|MDS
Interventions: DRUG: MT-401-OTS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Hepatocellular Carcinoma (HCC) With Octanoate Breath ID Test Compared to MRI
Status: TERMINATED
Conditions: Chronic Liver Disease|Hepatocellular Carcinoma (HCC)
Interventions: DRUG: 13C Sodium Octanoate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Effectiveness Evaluation of iCover Covered Stent for the Treatment of the Aorto-iliac Occlusive Disease
Status: NOT_YET_RECRUITING
Conditions: Angioplasty|Peripheral Arterial Disease|Iliac Artery Disease|Covered Stent|Aorto-Iliac Atherosclerosis
Interventions: DEVICE: Covered stent implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiation During Osimertinib Treatment: a Safety and Efficacy Cohort Study
Status: RECRUITING
Conditions: NSCLC|EGFR Positive Non-small Cell Lung Cancer|Oligoprogression
Interventions: DRUG: Osimertinib|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Hepatitis A Among People Aged 18-50 Years Old
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatitis A
Interventions: BIOLOGICAL: Healive (hepatitis A vacine(human diploid cell), inactivated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Improving Pain Management and Long Term Outcomes Following High Energy Orthopedic Trauma (Pain Study)
Status: COMPLETED
Conditions: Orthopaedic Fractures
Interventions: DRUG: NSAID|DRUG: Gabapentinoids|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nicotinamide Riboside in SARS-CoV-2 (COVID-19) Patients for Renal Protection
Status: COMPLETED
Conditions: SARS-CoV-2 Infection|Acute Kidney Injury
Interventions: DRUG: Placebo|DRUG: Nicotinamide riboside
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Parameters of Innovative Valganciclovir Versus Generic Valganciclovir
Status: COMPLETED
Conditions: Kidney Transplantation|Cytomegalovirus Infections|Pharmacokinetics|Therapeutic Equivalency
Interventions: DRUG: Generic Valganciclovir|DRUG: Innovative Valganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Protective Efficacy of Intravenous Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chemoprophylaxis
Status: COMPLETED
Conditions: Malaria|Plasmodium Falciparum Malaria
Interventions: BIOLOGICAL: PfSPZ Challenge|BIOLOGICAL: 0.9% Sodium Chloride (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Hypothyroidism Incidence After Breast Cancer Supraclavicular Irradiation
Status: COMPLETED
Conditions: Irradiation; Adverse Effect|Irradiation Hypothyroidism
Interventions: BIOLOGICAL: biological sample|RADIATION: supraclavicular irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Gemcitabine and Cisplatin Without Cystectomy for Patients With Muscle Invasive Bladder Urothelial Cancer and Select Genetic Alterations
Status: RECRUITING
Conditions: Infiltrating Bladder Urothelial Carcinoma|Stage II Bladder Urothelial Carcinoma|Stage III Bladder Urothelial Carcinoma
Interventions: DRUG: Gemcitabine Hydrochloride|DRUG: Cisplatin|BIOLOGICAL: Pegfilgrastim|PROCEDURE: Conventional Surgery|PROCEDURE: Radical Cystectomy|OTHER: Chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-Range Finding Clinical Trial Study in Human Immunodeficiency Virus (HIV-1) Infected Treatment-Naive Adults
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: GSK3640254|DRUG: ABC/3TC|DRUG: FTC/TAF|DRUG: Dolutegravir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pericapsular Nerve Block and Iliopsoas Fascial Plane Block in Hip Surgery
Status: RECRUITING
Conditions: Hip Fractures|Peripheral Nerve Block
Interventions: PROCEDURE: PENG block|PROCEDURE: IPB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose-finding Study of GLPG0634 as Monotherapy in Active Rheumatoid Arthritis (RA) Participants (DARWIN2)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: GLPG0634|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Multiple-Dose Ritlecitinib on the Pharmacokinetics (PK) of Tolbutamide
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Ritlecitinib|DRUG: Tolbutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial of Obinutuzumab,GDC-0199 Plus Ibrutinib in Relapsed/Refractory Mantle Cell Lymphoma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Ibrutinib + GA101 +GDC-0199
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetically Modified T Cells in Treating Patients With Stage III-IV Non-small Cell Lung Cancer or Mesothelioma
Status: TERMINATED
Conditions: Advanced Pleural Malignant Mesothelioma|HLA-A*0201 Positive Cells Present|Recurrent Non-Small Cell Lung Carcinoma|Recurrent Pleural Malignant Mesothelioma|Stage III Non-Small Cell Lung Cancer AJCC v7|Stage III Pleural Malignant Mesothelioma AJCC v7|Stage IIIA Non-Small Cell Lung Cancer AJCC v7|Stage IIIB Non-Small Cell Lung Cancer AJCC v7|Stage IV Non-Small Cell Lung Cancer AJCC v7|Stage IV Pleural Malignant Mesothelioma AJCC v7|WT1 Positive
Interventions: BIOLOGICAL: Aldesleukin|BIOLOGICAL: Autologous WT1-TCRc4 Gene-transduced CD8-positive Tcm/Tn Lymphocytes|DRUG: Cyclophosphamide|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NY-ESO-1-specific T Cell Receptor (TCR) T Cell in Sarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Bone Sarcoma|Soft Tissue Sarcoma
Interventions: BIOLOGICAL: NY-ESO-1（TCR Affinity Enhancing Specific T cell Therapy）
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sodium Nitroprusside for Blood Pressure Reduction in the ICU (SNP2)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: nitroprusside|DRUG: placebo infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Good Pain Management (GPM) Ward Program on Moderate to Severe Cancer Pain Patients
Status: UNKNOWN
Conditions: Cancer|Pain
Interventions: OTHER: Good pain management (GPM) procedure|OTHER: Current practice procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Immunogenicity Study of Thiomersal-free Hepatitis E Vaccine in People Ages 16 Years and Above
Status: COMPLETED
Conditions: Hepatitis E
Interventions: BIOLOGICAL: Thiomersal-free Recombinant Hepatitis E Vaccine (Escherichia Coli)|BIOLOGICAL: Recombinant Hepatitis E Vaccine (Escherichia Coli)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Controlled Trial on the Effect of Needle Gauge on the Pain and Anxiety Experienced During Arterial Puncture
Status: COMPLETED
Conditions: Blood Gas Analysis|Pain
Interventions: PROCEDURE: 23Gauge|PROCEDURE: 25Gauge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Insertion Depth of Left-sided Double-lumen Tube: a New Predictive Formula
Status: COMPLETED
Conditions: Thoracic Surgery|One Lung Ventilation|Left-sided Double Lumen Tube
Interventions: OTHER: Predicted depth of insertion|OTHER: Optimized depth of insertion|OTHER: Adjustment of depth of insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Pharmacokinetics Study of MK-7655A in Pediatric Participants With Gram-negative Infections (MK-7655A-020)
Status: COMPLETED
Conditions: Suspected or Documented Gram-negative Bacterial Infection
Interventions: DRUG: IMI/REL FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ginseng in Decreasing Cancer-Related Fatigue After Treatment in Cancer Survivors
Status: COMPLETED
Conditions: Cancer Survivor|Stage I Breast Cancer AJCC v7|Stage I Colon Cancer AJCC v6 and v7|Stage IA Breast Cancer AJCC v7|Stage IB Breast Cancer AJCC v7|Stage II Breast Cancer AJCC v6 and v7|Stage II Colon Cancer AJCC v7|Stage IIA Breast Cancer AJCC v6 and v7|Stage IIA Colon Cancer AJCC v7|Stage IIB Breast Cancer AJCC v6 and v7|Stage IIB Colon Cancer AJCC v7|Stage IIC Colon Cancer AJCC v7|Stage III Breast Cancer AJCC v7|Stage III Colon Cancer AJCC v7|Stage IIIA Breast Cancer AJCC v7|Stage IIIA Colon Cancer AJCC v7|Stage IIIB Breast Cancer AJCC v7|Stage IIIB Colon Cancer AJCC v7|Stage IIIC Breast Cancer AJCC v7|Stage IIIC Colon Cancer AJCC v7
Interventions: DRUG: American Ginseng|OTHER: Laboratory Biomarker Analysis|OTHER: Placebo|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Twice Daily 60mg AZD9668 in COPD for 12 Weeks in Patients on Background Budesonide/Formoterol
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: AZD9668|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Phase 3 Study to Evaluate Two Formulations of Romosozumab in Postmenopausal Women With Osteoporosis
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Romosozumab 90 mg/mL|DRUG: Placebo 90 mg/mL|DRUG: Romosozumab 70 mg/mL|DRUG: Placebo 70 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trilaciclib (G1T28), a CDK 4/6 Inhibitor, in Combination With Gemcitabine and Carboplatin in Metastatic Triple Negative Breast Cancer (mTNBC)
Status: TERMINATED
Conditions: Triple-Negative Breast Neoplasms|Breast Neoplasm|Breast Cancer|Triple-Negative Breast Cancer
Interventions: DRUG: Trilaciclib|DRUG: Gemcitabine|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Infusion in Hystroscopy
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Lidocaine Hydrochloride|DRUG: Diclofenac Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiostereometric Analysis of Acetabular Wear and Periprosthetic Bone Mineral Density Changes in Hemiarthroplasties
Status: UNKNOWN
Conditions: Femoral Neck Fractures|Bone Density|Acetabular Wear|Hemiarthroplasty
Interventions: PROCEDURE: Cemented primary bipolar hemiarthroplasty of the hip|PROCEDURE: Uncemented primary bipolar hemiarthroplasty of the hip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TRANSforming InTerprofessional Cardiovascular Prevention in Primary Care
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Hypertension|Dyslipidemias|Cholesterol, LDL|Comorbitdity
Interventions: OTHER: Facilitation|OTHER: Passive diffusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Emotional Freedom Technique (EFT) Effect on Nurses
Status: UNKNOWN
Conditions: Anxiety, Covid-19 Fear
Interventions: BEHAVIORAL: Emotional Freedom Techniques (EFT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Home-based Brain Stimulation Treatment for Post-acute Sequelae of COVID-19 (PASC)
Status: RECRUITING
Conditions: Dysexecutive Syndrome|Post-Acute Sequelae of COVID-19
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy of Cerebellar IMRT Combined With Cerebral SRS in Patients With Brain Metastases
Status: RECRUITING
Conditions: Brain Metastases|Posterior Fossa Lesion|Cerebral Lesion
Interventions: RADIATION: Radiation treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Managing the Nutritional Needs of Older Filipino With Due Attention to Protein Nutrition and Functional Health Study
Status: ENROLLING_BY_INVITATION
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Nutrition supplementation|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Atezolizumab, Cobimetinib, and Eribulin in Treating Patients With Chemotherapy Resistant Metastatic Inflammatory Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Breast Inflammatory Carcinoma|Stage IV Breast Inflammatory Carcinoma
Interventions: DRUG: Atezolizumab|DRUG: Cobimetinib|DRUG: Eribulin|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing Rocatinlimab on Vaccine Antibody Response in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET - VOYAGER)
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis|Moderate-to-severe Atopic Dermatitis
Interventions: DRUG: Rocatinlimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Effect of Hydration About Orthostatic Hypotension in the Elderly. Difference With Venous Compression
Status: UNKNOWN
Conditions: Orthostatic Hypotension
Interventions: OTHER: Hydration|OTHER: Venous contention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Obesity
Status: UNKNOWN
Conditions: Overweight and Obesity|Overweight or Obesity|Obesity|Obesity, Morbid|Obesity, Abdominal|Obesity; Familial|Obesity; Endocrine|Obesity, Visceral|Obesity Hypoventilation Syndrome
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Risk Neuroblastoma Study 1.8 of SIOP-Europe (SIOPEN)
Status: RECRUITING
Conditions: Neuroblastoma
Interventions: DRUG: Vincristine|DRUG: Aldesleukin|DRUG: ch14.18/CHO|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Cisplatin|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: G-CSF|DRUG: Busulfan|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of COVID-19 Outbreak in Hospital Departments of Bamako, Mali
Status: UNKNOWN
Conditions: Covid19
Interventions: DIAGNOSTIC_TEST: SARS-CoV-2 screening by molecular biology|DIAGNOSTIC_TEST: Serological screening
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Evaluation of Effectivity of Erector Spina Plane Block With Different Levels
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: T7 Level Erector Spinae Plane Block|PROCEDURE: T9 Level Erector Spinae Plane Block|DRUG: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Effectiveness of AZLI (an Inhaled Antibiotic) in Adults With Non-Cystic Fibrosis Bronchiectasis
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: DRUG: AZLI|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiosensitizing Effect of Nelfinavir in Locally Advanced Carcinoma of Cervix
Status: RECRUITING
Conditions: Carcinoma Cervix,Stage III
Interventions: DRUG: Nelfinavir|DRUG: Cisplatin|RADIATION: Pelvic EBRT and Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytoreduction With or Without Intraoperative Intraperitoneal Hyperthermic Chemotherapy (HIPEC) in Patients With Peritoneal Carcinomatosis From Ovarian Cancer, Fallopian Tube or Primary Peritoneal Carcinoma
Status: UNKNOWN
Conditions: Peritoneal Carcinomatosis From Ovarian Cancer|Fallopian Tube Carcinoma|Primary Peritoneal Carcinoma
Interventions: PROCEDURE: Cytoreduction|DRUG: Hipec with Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Ontogeny of Measles Immunity in Infants
Status: COMPLETED
Conditions: Measles
Interventions: BIOLOGICAL: Attenuvax (Measles Virus Live Vaccine, 0.5ml subcutaneous)|BIOLOGICAL: MMR-II (Measles-Mumps-Rubella Virus Live Vaccine, 0.5ml subcutaneous)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Flexible Tape in Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: OTHER: Flexible tape|OTHER: Fixomull|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Association of FGF-23 and Parathyroid Hormone (PTH) in Dialysis Patients
Status: COMPLETED
Conditions: End-Stage Renal Disease
Interventions: PROCEDURE: exposure to a high-calcium dialysate bath
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Heel-unloading Orthosis for Treatment of Calcaneus Fractures
Status: UNKNOWN
Conditions: Calcaneus Fracture|Orthopedic Devices Associated With Misadventures
Interventions: DEVICE: Settner shoe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Levothyroxine Sodium in Thyroidectomized Patients Taking Proton Pump Inhibitors
Status: COMPLETED
Conditions: Hypothyroidism;Postablative
Interventions: DRUG: levothyroxine sodium capsule|DRUG: Proton pump inhibitor (PPI)|DRUG: Levothyroxine Sodium (LT4) Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Liposomal Bupivacaine for TKA
Status: COMPLETED
Conditions: Knee Replacement|Total Knee Arthroplasty|Post-Operative Pain
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Type A Botulinum Toxin Injection and Corticosteroid Injection in the Treatment of Tennis Elbow
Status: UNKNOWN
Conditions: Type A Botulinum Toxin|Tennis Elbow
Interventions: DRUG: Botox (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT