pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Impact of Phone Call About Financial Reimbursement Program on Access to Cancer Clinical Trials
Status: TERMINATED
Conditions: Malignant Neoplasm|Hematopoietic and Lymphoid Cell Neoplasm
Interventions: BEHAVIORAL: Cancer Educational Materials|OTHER: Follow-Up Care|BEHAVIORAL: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: RCT (Randomized Controlled Trial) of IV Acetaminophen for Post Cesarean Pain Relief
Status: COMPLETED
Conditions: Cesarean Section|Pain, Postoperative
Interventions: DRUG: IV Acetaminophen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Atezolizumab Plus BEGEV Regimen in Relapsed or Refractory Hodgkin's Lymphoma Patients
Status: RECRUITING
Conditions: Relapsed or Refractory Hodgkin's Lymphoma
Interventions: DRUG: Atezolizumab|COMBINATION_PRODUCT: BEGEV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Self-Help for Dually-Diagnosed Persons - 1
Status: COMPLETED
Conditions: Dual Diagnosis|Substance-Related Disorders|Mental Disorders
Interventions: BEHAVIORAL: Double Trouble in Recovery|BEHAVIORAL: Standard psychiatric day treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clofarabine and Cytarabine in Treating Older Patients With AML or High-Risk MDS
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Myelodysplastic Syndrome With Isolated Del(5q)|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Myeloid Leukemia
Interventions: DRUG: clofarabine|DRUG: cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (PATHFNDR-2)
Status: ACTIVE_NOT_RECRUITING
Conditions: Acromegaly
Interventions: DRUG: Paltusotine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Concurrent Exercise for Cardiovascular Risk Control and Fitness in Adults
Status: COMPLETED
Conditions: Cardiovascular Syndrome, Metabolic
Interventions: BEHAVIORAL: Concurrent training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Piperaquine Granule Formulation Relative Bioavailability and Food Effect Study in Healthy Volunteers.
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Piperaquine Phosphate|DRUG: Piperaquine Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Telemonitoring on Anxiety and Quality of Life in Patients in COVID 19 Quarantine
Status: COMPLETED
Conditions: COVID-19 Pandemic
Interventions: OTHER: tele-monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Extension Study of Belcesiran in Patients With Alpha-1 Antitrypsin Deficiency Associated Liver Disease (AATLD)
Status: WITHDRAWN
Conditions: Alpha 1-Antitrypsin Deficiency
Interventions: DRUG: Belcesiran
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Accuracy Evaluation of Implant Impressions: A Prospective Study
Status: NOT_YET_RECRUITING
Conditions: Edentulous Jaw|Dental Implants|Edentulous Mouth
Interventions: PROCEDURE: Accuracy of full-arch implant impressions|PROCEDURE: Accuracy of full-arch implant impressions using intraoral scanners
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 6-week Study in Asthmatic Children Aged 6 to <12 Yrs Comparing Budesonide pMDI 160ug Twice Daily With Placebo
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: budesonide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microbiome and Exacerbations in Neutrophilic Asthma
Status: RECRUITING
Conditions: Asthma|Microbiome|Exacerbation
Interventions: DIAGNOSTIC_TEST: Polymerase Chain Reaction (PCR) for viruses and bacteria in nasal swab|DIAGNOSTIC_TEST: Induced sputum microbiome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study to Investigate the Effect on Pain Relief of a Single Dose of JNJ-39439335 in Patients With Chronic Osteoarthritis Pain of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: JNJ-39439335; Placebo; Naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Technological Innovation in the Virtual Assistance of Patients With Uncontrolled Arterial Hypertension - Hyper 2
Status: ACTIVE_NOT_RECRUITING
Conditions: Essential Hypertension|Metabolic Cardiovascular Syndrome|Heart Disease Risk Factors
Interventions: DEVICE: Using the Avatr App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Clinical Standardization Study of the Preferred Acupuncture Treatment Protocol to Treat Functional Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: OTHER: deep needling|DRUG: Lactulose|OTHER: shallow needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of an Interactive Web-Based Home Therapy Program After Stroke
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke
Interventions: BEHAVIORAL: Web-based Home Exercise Program|BEHAVIORAL: Standard Home Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Substudy of the Accuracy of Ingestible Event Marker (IEM) Detection by the Medical Information Device #1 (MIND1)
Status: COMPLETED
Conditions: Device Latency
Interventions: DRUG: Placebo|COMBINATION_PRODUCT: Combination product of Aripiprazole + IEM + Sensor + MIND1 Application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Nerve Blocks for Major Lower Extremity Amputations
Status: TERMINATED
Conditions: Postoperative Pain
Interventions: DRUG: Bupivacaine|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Fluocinolone Acetonide Intravitreal Implant
Status: TERMINATED
Conditions: Non-infectious Uveitis
Interventions: DRUG: Fluocinolone Acetonide 0.59mg|DRUG: Fluocinolone Acetonide 2.1mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab (MK-3475) in Combination With Romidepsin
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Anaplastic Large Cell Lymphoma|Recurrent Angioimmunoblastic T-Cell Lymphoma|Recurrent Mature T- and NK-Cell Non-Hodgkin Lymphoma|Recurrent Mycosis Fungoides|Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma|Refractory Anaplastic Large Cell Lymphoma|Refractory Angioimmunoblastic T-Cell Lymphoma|Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma|Refractory Mycosis Fungoides|Refractory Peripheral T-Cell Lymphoma, Not Otherwise Specified|Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Romidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Press Needle Acupoint Stimulation Combined With Breast Massage on the Initiation of Lactogenesis II
Status: COMPLETED
Conditions: Lactation Induced
Interventions: OTHER: Press Needle Acupoint Stimulation Combined with Breast Massage|OTHER: routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy in Treating Patients With Previously Untreated, Newly Diagnosed Epithelial Tumors
Status: COMPLETED
Conditions: Endometrial Cancer|Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: carboplatin|DRUG: docetaxel|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Haloperidol Versus Ondansetron for Cannabis Hyperemesis Syndrome (HaVOC)
Status: COMPLETED
Conditions: Cannabis Use Disorder
Interventions: DRUG: Ondansetron 8mg|DRUG: Haloperidol 0.05mg/kg|DRUG: Haloperidol 0.1mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Gallium-68-HBED-CC-PSMA Imaging in Prostate Cancer Patients
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Ga-68 labeled HBED-CC PSMA|DEVICE: Positron Emission Tomography (PET) image combined with Computed Tomography (CT) (PET/CT)|DEVICE: Positron Emission Tomography (PET) image combined with Magnetic Resonance Imaging (MRI) (PET/MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Preventing Propofol-associated Injection Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Saline|DRUG: Lidocaine / propofol admixture|DRUG: lidocaine pretreatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Registry of Coronary Flow-Derived Indexes for Coronary Microvascular Disease (Multicenter FLOW-CMD Registry)
Status: RECRUITING
Conditions: Coronary Microvascular Disease|Coronary Artery Disease|Ischemic Heart Disease
Interventions: DIAGNOSTIC_TEST: Invasive physiologic assessment|DIAGNOSTIC_TEST: Intravascular imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Intervention in Mild Cognitive Impairment (MCI) With Curcumin + Bioperine
Status: TERMINATED
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: curcumin + bioperine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intraocular Pressure Changes Associated With Tracheal Extubation: Comparison of Sugammadex With Conventional Reversal of Neuromuscular Blockade
Status: COMPLETED
Conditions: Intraocular Pressure Changes During Tracheal Extubation
Interventions: DRUG: sugammadex|DRUG: neostigmine+atropine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Autologous Osteoperiosteal Transplantation for the Treatment of Severe Osteochondral Lesions of the Talus
Status: RECRUITING
Conditions: Osteochondral Lesion of Talus|Autologous Osteoperiosteal Transplantation
Interventions: PROCEDURE: Autologous Osteoperiosteal Transplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prospective, Multicentric, Phase II Randomized Controlled Trial on Two Parallel Groups Comparing the Efficacy of Two Immunosuppressive Drugs (Methotrexate, Cyclophosphamide) in Large Granular Lymphocytes Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Large Granular Lymphocytes Leukemia
Interventions: DRUG: Methotrexate|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Test Bioequivalence Between Two Tablet Formulations in the Treatment of Allergy
Status: COMPLETED
Conditions: Allergy
Interventions: DRUG: Cetirizine|DRUG: Cetirizine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Medication Trial Combined With Behavior Therapy for Individuals With Obsessive-compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: behavior therapy|DRUG: D-Cycloserine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Patient Reported Outcomes in RRMS Patients Candidates for MS Therapy Change and Transitioned to Fingolimod 0.5 mg (EPOC)
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: Fingolimod|DRUG: Interferon beta - 1a (IFN)|DRUG: Glatiramer acetate (GA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FLOX + Cetuximab (Erbitux®) for Patients With Metastatic Colorectal Cancer and Wild Type K-RAS Tumor
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Cetuximab (Erbitux)|DRUG: Oxaliplatin (Eloxatin) + Fluorouracil + folinic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-dose Radiotherapy Combined With Conventional Radiotherapy After Immunotherapy Failure
Status: UNKNOWN
Conditions: Cancer Patients
Interventions: RADIATION: At the same time, the original regimen of immunomaintenance therapy was continued, according to the frequency of the original immunization regimen once every 3 weeks until progress.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Immersive Virtual Reality in Functional Rehabilitation in Older People With Knee Arthroplasty
Status: UNKNOWN
Conditions: Arthroplasty, Replacement, Knee
Interventions: OTHER: Physioterapy rehabilitation with IVR|OTHER: standard physiotherapy rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Alendronate on Vascular Calcification and Arterial Stiffness in Chronic Kidney Disease
Status: COMPLETED
Conditions: Vascular Calcification|Arteriosclerosis
Interventions: DRUG: Alendronate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Serotonin, Serotonin Genetics(TPH2) and Emotion and Interference Processing
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: ATD treatment|DRUG: placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Aridol Challenge as a Tool to Predict Treatment Response to Inhaled Corticosteroids in COPD
Status: COMPLETED
Conditions: Lung Diseases, Obstructive
Interventions: DRUG: Dry powder mannitol|DRUG: Budesonide 400mcg administered via turbuhaler|DRUG: Ipratropium bromide 80mcg|DRUG: Salbutamol 400mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Donafenib for Previously Treated Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Donafenib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High Flow Nasal Cannula Is Appropriate Alternative for Stabilization of Very Premature Infants: A Prospective Observational Study
Status: COMPLETED
Conditions: Premature; Infant
Interventions: DEVICE: High-Flow Nasal Cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Combination Therapy for Chronic Hepatitis C Infection
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Sofosbuvir|DRUG: Ledipasvir|DRUG: GS-9669|DRUG: GS-9451
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temozolomide Combine With Intensity Modulated Radiation Therapy With Simultaneous Integrated Boost for Non Small Cell Lung Cancer Brain Metastases
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer Metastatic
Interventions: DRUG: Temozolomide capsules|DEVICE: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Living With Statins - The Impact of Cholesterol Lowering Drugs on Health, Lifestyle and Well-being
Status: COMPLETED
Conditions: Cardiovascular Disease|Diabetes Mellitus
Interventions: DRUG: Simvastatin|DIETARY_SUPPLEMENT: Q10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ADXS 11-001 Vaccination Prior to Robotic Surgery, HPV-Positive Oropharyngeal Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Squamous Cell Carcinoma of the Head and Neck|HPV Positive Oropharyngeal Squamous Cell Carcinoma
Interventions: BIOLOGICAL: ADXS11-001 (ADXS-HPV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Assess Safety and Efficacy of Daratumumab in the Treatment of Primary Immune Thrombocytopenia
Status: UNKNOWN
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Daratumumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Verify the Accuracy of Seers Technology's Pulse Oximeter (mobiCARE +Pulse, MP100W) in Healthy Volunteers
Status: COMPLETED
Conditions: Oxygen Saturation
Interventions: DEVICE: mobiCARE +Pulse (MP100W)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A HAPA-based Multicomponent Fall Intervention on Older Adults With Declines in Intrinsic Capacity in Nursing Homes
Status: ACTIVE_NOT_RECRUITING
Conditions: Fall Risk
Interventions: BEHAVIORAL: HAPA-based multicomponent fall intervention|BEHAVIORAL: Regular health education lectures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: MACT (Mono Antiplatelet and Colchicine Therapy) Prospective Multicenter Study
Status: RECRUITING
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Colchicine 0.6 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Displaced, Midshaft Clavicle Fractures. Sling or Plate?
Status: COMPLETED
Conditions: Acute, Displaced Midshaft Clavicle Fractures
Interventions: PROCEDURE: Conservative Treatment|PROCEDURE: Surgical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peri-operative Azithromycin to Improve Early Allograft Function and Outcome After Lung Transplantation
Status: COMPLETED
Conditions: Disorder Related to Lung Transplantation
Interventions: DRUG: Azithromycin|DRUG: Ora-Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Static Ultrasound-Preview Reduce the Incidence of Difficult Lumbar Puncture?
Status: TERMINATED
Conditions: Headache|Meningitis|Subarachnoid Hemorrhage
Interventions: DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: S1613, Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Colon Adenocarcinoma|ERBB2 Gene Amplification|Rectal Adenocarcinoma|Recurrent Colon Carcinoma|Recurrent Rectal Carcinoma|Stage III Colon Cancer AJCC v7|Stage III Rectal Cancer AJCC v7|Stage IIIA Colon Cancer AJCC v7|Stage IIIA Rectal Cancer AJCC v7|Stage IIIB Colon Cancer AJCC v7|Stage IIIB Rectal Cancer AJCC v7|Stage IIIC Colon Cancer AJCC v7|Stage IIIC Rectal Cancer AJCC v7|Stage IV Colon Cancer AJCC v7|Stage IV Rectal Cancer AJCC v7|Stage IVA Colon Cancer AJCC v7|Stage IVA Rectal Cancer AJCC v7|Stage IVB Colon Cancer AJCC v7|Stage IVB Rectal Cancer AJCC v7
Interventions: BIOLOGICAL: Cetuximab|DRUG: Irinotecan Hydrochloride|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pertuzumab|BIOLOGICAL: Trastuzumab|DEVICE: HER-2 testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Lymphoblastic Leukemia Registry at Asan Medical Center
Status: TERMINATED
Conditions: Leukemia, Acute Lymphoblastic|Precursor B-Cell Lymphoblastic Leukemia|Leukemia, Biphenotypic, Acute|Leukemia, Lymphoblastic, Acute, Philadelphia-Positive|Lymphoblastic Lymphoma
Interventions: OTHER: Diagnosed as ALL
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Safety, Tolerability and Pharmacokinetic of Single and 14 Day Repeat Topical Application of GSK1940029
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: 0.3% GSK1940029 gel|DRUG: 1% GSK1940029 gel|DRUG: 0.3%/1% vehicle gel only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of ADCT-301 in Patients With Selected Advanced Solid Tumors
Status: TERMINATED
Conditions: Head and Neck Cancer Squamous Cell Carcinoma|Non-small Cell Lung Cancer|Gastric Cancer|Esophageal Cancer|Pancreas Cancer|Bladder Cancer|Renal Cell Carcinoma|Melanoma|Triple-negative Breast Cancer|Ovarian Cancer|Colo-rectal Cancer|Fallopian Tube Cancer
Interventions: DRUG: ADCT-301|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Platelet-rich Plasma in Pilonidal Sinus Disease
Status: COMPLETED
Conditions: Pilonidal Sinus|Pilonidal Disease|Wound Heal|Quality of Life|Pain
Interventions: PROCEDURE: Open surgery|PROCEDURE: Minimal invasive surgery|OTHER: Platelet rich plasma administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cancer Venous Thromboembolism (VTE)
Status: COMPLETED
Conditions: Venous Thromboembolism (VTE)|Deep Vein Thrombosis (DVT)|Pulmonary Embolism (PE)|Cancer
Interventions: DRUG: Edoxaban|DRUG: Dalteparin|DRUG: Low molecular weight heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PSODEEP2 Pilot Study on Koebner Induction in Psoriasis
Status: NOT_YET_RECRUITING
Conditions: Psoriasis Vulgaris|Koebner Phenomenon
Interventions: OTHER: Tape-stripping
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Double Blind Sham-controled Study to Evaluate the Influence of Low Frequency Repetitive Transcranial Stimulation (r-TMS) on Motor and Cognitive Measurements in Patients With Asymmetric Parkinson's Disease
Status: UNKNOWN
Conditions: Asymmetric Parkinson's Disease
Interventions: DEVICE: repetitive transcranial stimulation (r-TMS)|DEVICE: repetitive transcranial stimulation (r-TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Impact of Rapid Prototyping 3D Models for Surgical Management
Status: WITHDRAWN
Conditions: Double Outlet Right Ventricle|Transposition of the Great Arteries|Truncus Arteriosus|Congenitally Corrected Transposition of the Great Arteries
Interventions: DIAGNOSTIC_TEST: 3D Printed Heart Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Urethral Stricture With Urethral Drug Ball
Status: RECRUITING
Conditions: Urethral Stricture Less Than 2 cm
Interventions: PROCEDURE: Drug balloon dilatation|PROCEDURE: Direct vision internal urethrotomy (DVIU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of a Recombinant and Protein-Free Factor VIII (rAHF-PFM) in Pediatric Patients in Canada With Hemophilia A - A Continuation of Baxter Study 060101
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: Antihemophilic Factor Manufactured and Formulated without Added Human or Animal Proteins (rAHF-PFM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Combined With Eribulin Regimen in the Treatment of Second-line Above Recurrent HER2-negative Breast Cancer
Status: UNKNOWN
Conditions: HER2-negative Breast Cancer
Interventions: DRUG: Gemcitabine combined with eribulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Children With Autistic Spectrum Disorder With Autologous Umbilical Cord Blood, a Pilot Study
Status: RECRUITING
Conditions: Autistic Spectrum Disorder
Interventions: BIOLOGICAL: Autologous umbilical cord blood|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-Arm Study of Pembrolizumab With Gemcitabine and Cisplatin as Perioperative Therapy for Potentially Resectable Intrahepatic Cholangiocarcinoma
Status: RECRUITING
Conditions: Cholangiocarcinoma
Interventions: DRUG: Pembrolizumab|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EMST and TMS for Treatment of Dysphagia in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DEVICE: Expiratory muscle strength training (EMST)|OTHER: Transcranial magnetic stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic vs. Robotic Ventral Hernia Repair With IPOM
Status: COMPLETED
Conditions: Ventral Hernia
Interventions: DEVICE: Robotic Ventral Hernia Repair with IPOM|DEVICE: Laparoscopic Ventral Hernia Repair with IPOM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Auricular Acupressure on the Improvement of Anxiousness, Depression and Heart Rate Variability in Stroke Patients
Status: UNKNOWN
Conditions: Post-stroke Depression|Auricular Acupressure
Interventions: OTHER: auricular acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Histidine-tryptophan-ketoglutarate Cardioplegia and Cold Blood Cardioplegia for Myocardial Protection for Fallot Tetralogy Patients Undergoing Total Repair
Status: UNKNOWN
Conditions: Anesthesia
Interventions: DRUG: HTK cardioplegia|DRUG: Cold Cadioplegia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mindful Moment: Feasibility and Preliminary Efficacy of a Web-based Mindful and Compassionate Parenting Training
Status: COMPLETED
Conditions: Parenting Stress
Interventions: BEHAVIORAL: Mindful Moment|OTHER: Waiting-List Control (WLC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Imagery Rescripting for Posttraumatic Nightmares in Rural Operation Enduring Freedom (OEF)/Operation Iraqi Freedom (OIF) Veterans With Posttraumatic Stress Disorder (PTSD)
Status: TERMINATED
Conditions: Stress Disorders, Post-Traumatic|Sleep Disorders
Interventions: BEHAVIORAL: MEDVAMC Nightmare Treatment|BEHAVIORAL: Telepsychiatry Nightmare Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methotrexate Combined With Immunotherapy During Radiotherapy for Solid Tumors
Status: RECRUITING
Conditions: Solid Tumors
Interventions: DRUG: Methotrexate tablets|DRUG: Anti-PD-1 monoclonal antibody|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Palbociclib in Second Line of Advanced Sarcomas With CDK4 Overexpression.
Status: RECRUITING
Conditions: Soft-tissue Sarcoma|Osteosarcoma|Chordoma
Interventions: DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac and Immune Cell Function in Preeclampsia
Status: RECRUITING
Conditions: Preeclampsia|Hypertension|Pregnancy Induced Hypertension|Pregnancy Related|Cardiovascular Diseases|Cardiovascular Risk Factor|Heart Diseases
Interventions: DIAGNOSTIC_TEST: Cardiovascular magnetic resonance|DIAGNOSTIC_TEST: Echocardiography|DIAGNOSTIC_TEST: Blood test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interscalene Bupivacaine With Either Liposomal Bupivacaine or Continuous Peripheral Nerve Block for Shoulder Arthroscopy
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: PROCEDURE: Single-injection bupivacaine HCl plus liposomal bupivacaine|PROCEDURE: Single-injection bupivacaine HCl plus a subsequent bupivacaine CISB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Focused Lung Ultrasonography on Antibiotic Prescribing in General Practice
Status: ACTIVE_NOT_RECRUITING
Conditions: Lower Respiratory Tract Infection|Community Acquired Pneumonia
Interventions: DIAGNOSTIC_TEST: Focused lung ultrasound (FLUS)|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Systemic Therapy With or Without Upfront Transarterial Embolization for Inoperable Liver Metastasis of Neuroendocrine Tumors
Status: TERMINATED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: approved pharmacologic therapy|PROCEDURE: TAE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Volumetric Hemodynamic Parameters Induced by Fluid Removal on Hemodialysis
Status: COMPLETED
Conditions: End Stage Renal Failure on Dialysis|Body Fluid Retention|Impedance|Cardiac Output, Low
Interventions: DEVICE: CardioScreen 1000 - Haemodynamic Measurement System, Medis|DEVICE: BCM- Body Composition Monitor, Fresenius Medical Care|DEVICE: SCHILLER, BR-102 plus, Ambulatory Blood Pressure Monitoring System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Transfer of Hospitalized Patients Incl. COVID-19 to a Virtual Hospital at Home Model - a Clinical Feasibility Study
Status: COMPLETED
Conditions: Telemedicine|Epidemic Disease
Interventions: OTHER: Virtual Hospital at Home - Home admission of epidemic patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of High-dose Oral Rabeprazole on Recurrent Bleeding After the Endoscopic Treatment of Bleeding Peptic Ulcers
Status: TERMINATED
Conditions: Peptic Ulcer Hemorrhage
Interventions: DRUG: omeprazole sodium IV|DRUG: Rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Orally Administered Curcuminoids in Adult Subjects With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: standardized turmeric root extract
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testicular Versus Ejaculated Spermatozoa for IVF/ICSI in Men With High Sperm DNA Damage
Status: COMPLETED
Conditions: Infertility, Male|DNA Damage
Interventions: PROCEDURE: Intracytoplasmic sperm injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination Therapy
Status: RECRUITING
Conditions: Advanced Prostate Carcinoma|Metastatic Prostate Carcinoma|Prostate Carcinoma|Stage III Prostate Cancer AJCC v8|Stage IV Prostate Cancer AJCC v8
Interventions: PROCEDURE: Bright White Light Therapy|DRUG: Combination Drug Therapy|OTHER: Electronic Health Record Review|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chlorhexidine Mouthwash and Oral Nitrate in Adults With Pulmonary Hypertension
Status: WITHDRAWN
Conditions: Pulmonary Hypertension|Heart Failure With Normal Ejection Fraction|Pulmonary Heart Disease and Diseases of Pulmonary Circulation
Interventions: DRUG: Nitrates|DRUG: Chlorhexidine Gluconate Mouthwash|DRUG: Placebo Mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Tolcapone on Decision Making and Alcohol Intake in Alcohol Users
Status: COMPLETED
Conditions: Alcohol Abuse|Impulsive Behavior
Interventions: DRUG: Tolcapone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acupuncture for Pain Management After Hip or Knee Arthroplasty
Status: WITHDRAWN
Conditions: Pain|Postoperative Complications
Interventions: PROCEDURE: Acupuncture|PROCEDURE: Sham Acupuncture|PROCEDURE: Standard medical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improving Bowel Habits of Elderly With Probiotics and Non-probiotics
Status: UNKNOWN
Conditions: Diarrhea|Constipation
Interventions: DIETARY_SUPPLEMENT: Yakult|DIETARY_SUPPLEMENT: Dairy Peach Drink (AH Basic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Translation of Generator-Produced PET Tracer for Myocardial Perfusion Imaging-Dosimetry Group
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Ga-68 Galmydar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Postoperative Analgesic Effect of Combination With Dexmedetomidine in Fentanyl-based Intravenous Patient Controlled Analgesia Compared With Conventional Thoracic Epidural and Intravenous Patient Controlled Analgesia After Radical Open Gastrectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Dexmedetomidine|DRUG: Fentanyl 1|DRUG: Fentanyl 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Translating a Dementia Caregiver Intervention Into a Mobile Application
Status: COMPLETED
Conditions: Dementia|Alzheimer Disease|Caregiver Burnout
Interventions: BEHAVIORAL: CARE-Well App|BEHAVIORAL: Internet Links
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep High-Frequency Repetitive Transcranial Magnetic Stimulation for Smoking Cessation
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Smoking
Interventions: DEVICE: High frequency TMS|DEVICE: Sham TMS|DEVICE: Low frequency TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of an Educational Tool on Quality of Life and Anxiety in Parents of Children With Nut Allergy
Status: COMPLETED
Conditions: Child Allergy|Food Allergy
Interventions: BEHAVIORAL: "living with food allergy" educational booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Comparison of DDT2 Contact Lens and a Daily Disposable Contact Lens - Study 2
Status: COMPLETED
Conditions: Refractive Error|Myopia
Interventions: DEVICE: Verofilcon A contact lenses|DEVICE: Somofilcon A contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Regarding the Clinical Efficacy of Synatura® in Patients With Chronic Bronchitis Type COPD
Status: COMPLETED
Conditions: Bronchitis, COPD
Interventions: DRUG: Synatura® 15 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outpatient Total Joint Arthroplasty in Dedicated Daycare Facility vs Standard Patient Ward
Status: COMPLETED
Conditions: Arthropathy of Knee|Arthropathy of Hip
Interventions: OTHER: Mobilization at a dedicated daycare facility
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of IoC on Analgesia for Elderly Patients With Postoperative Effectiveness
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DEVICE: Angel-6000D Multiparameter Anesthesia Monitor (IoC)|DEVICE: BIS VISTA Monitor (BIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nociception Level-guided Remifentanil Dosing in Children During General Anesthesia
Status: RECRUITING
Conditions: Surgical Procedure, Unspecified
Interventions: DEVICE: The NOL monitor (Pain Monitoring Device monitor-PMD200™)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Quadratus Lumborum Block on Recovery Profile After Ventral Hernia Repair
Status: TERMINATED
Conditions: Pain, Postoperative|Opioid Use
Interventions: COMBINATION_PRODUCT: Quadratus Lumborum Block|PROCEDURE: Standard Medical Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)
Status: NOT_YET_RECRUITING
Conditions: Sickle Cell Disease
Interventions: BIOLOGICAL: Crizanlizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identifying Networks Underlying Compulsivity in Anorexia Nervosa for Targeting With Neuromodulation
Status: RECRUITING
Conditions: Anorexia Nervosa
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Dose-Escalation Study With ETI-204 in Adult Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ETI-204, "Anthim"|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LBL-2016 for Children or Adolescents in China
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoblastic Lymphoma
Interventions: DRUG: Prednisone,Vincristine, Pegylated-asparaginase, Cytarabine, Cyclophosphamide, Daunorubicin, 6-mercaptopurine|DRUG: 6-mercaptopurine,Methotrexate|DRUG: Dexamethasone,Vincristine, Pegylated-asparaginase, Cytarabine, Cyclophosphamide, Doxorubicin, 6-mercaptopurine|DRUG: Dexamethasone,Vincristine, Pegylated-asparaginase, Cytarabine, Cyclophosphamide, Methotrexate|DRUG: Dexamethasone, Vindesine, Methotrexate, Ifosfamide, Daunorubicin, Pegylated-asparaginase|DRUG: Dexamethasone, Cytarabine, Etoposide, Pegylated-asparaginase|DRUG: Methotrexate, 6-mercaptopurine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ribavirin to Enhance Hepatitis B Virus Nucleotide Analog Antiviral Activity
Status: UNKNOWN
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Ribavirin|DRUG: Tenofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib in Combination With Carboplatin and Paclitaxel in Treating Participants With Metastatic or Recurrent Head and Neck Squamous Cell Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Head and Neck Squamous Cell Carcinoma|Metastatic Squamous Cell Carcinoma of the Hypopharynx|Metastatic Squamous Cell Carcinoma of the Larynx|Metastatic Squamous Cell Carcinoma of the Oral Cavity|Metastatic Squamous Cell Carcinoma of the Oropharynx|Recurrent Head and Neck Squamous Cell Carcinoma|Recurrent Hypopharyngeal Squamous Cell Carcinoma|Recurrent Laryngeal Squamous Cell Carcinoma|Recurrent Oral Cavity Squamous Cell Carcinoma|Recurrent Oropharyngeal Squamous Cell Carcinoma
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Technology-Mediated Integrated Walking and Tai Chi Intervention on Physical Function in Veterans With COPD and Chronic Musculoskeletal Pain
Status: RECRUITING
Conditions: COPD|Chronic Musculoskeletal Pain
Interventions: BEHAVIORAL: Every Step Counts-Tai Chi|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mitomycin-c Application for PRK
Status: COMPLETED
Conditions: Myopia
Interventions: DRUG: mitomycin-C|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Dose Ranging Study of OPT-302 With Ranibizumab in Neovascular (Wet) AMD
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: BIOLOGICAL: OPT-302|BIOLOGICAL: ranibizumab|OTHER: sham intravitreal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychological Impact of Medical Evacuations on Families of Patients Admitted to Intensive Care Unit for Severe COVID-19
Status: COMPLETED
Conditions: COVID-19|Stress Disorders, Post-Traumatic
Interventions: OTHER: Revised Impact of Event Scale|OTHER: Hospital Anxiety and Depression scale|OTHER: 36-Item Short Form Survey|OTHER: satisfaction survey|OTHER: semi-directed interview with trusted person on the general experience of the patient's medical evacuation|OTHER: semi-directed interview with trusted person on the general experience of hospitalization in intensive care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Coenzyme A and Pantethine Capsule for Safety and Efficacy On Patients With Hyperlipidemia
Status: COMPLETED
Conditions: Hyperlipoproteinemia
Interventions: DRUG: Coenzyme A|DRUG: Pantethine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT