pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Clinical Trial of YH14642 in Patients With Chronic Periodontal Disease
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: YH14642 500mg Tab|DRUG: YH14642 500mg Tab|DRUG: YH14642 500mg Tab|DRUG: INSADOL[Zea mays L. extract] 35mg Tab|DRUG: DENTISTA[Doxycycline hyclate] 20mg Cap|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of N-acetylcysteine in Treating Cocaine Dependent Individuals - 1
Status: COMPLETED
Conditions: Cocaine-Related Disorders
Interventions: DRUG: N-Acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Connectivity and Social Cognition in Adolescent Girls With Borderline Personality Disorder, a Pilot Study
Status: WITHDRAWN
Conditions: Adolescent Behavior|Borderline Personality Disorder
Interventions: OTHER: Exploring the feasibility of learning during cognitive tasks (EEG-NIRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treatment of Plantar Keratosis With Medicinal Plant in Diabetic Patients
Status: COMPLETED
Conditions: Keratosis Plantaris
Interventions: DRUG: Medicinal Plant|DRUG: Salicylate|DRUG: Vaseline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Use of Prompts to Increase Adolescent Immunization Rates
Status: COMPLETED
Conditions: Vaccine Preventable Diseases|Meningococcal Disease|Human Papillomavirus|Pertussis|Influenza
Interventions: OTHER: Point-of-Care Prompt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Compare the Bioavailability of Intravenously Infused Risankizumab Manufactured by Two Different Processes in Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Risankizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pentosan Polysulfate in Treating Patients With Gastrointestinal Disturbance Caused by Radiation Therapy
Status: COMPLETED
Conditions: Diarrhea|Radiation Enteritis
Interventions: DRUG: pentosan polysulfate sodium|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A First-in-Human Study to Assess Single and Multiple Doses of NXC736 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: NXC736|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Investigate the Influence of Hepatic Impairment on MK-8189 Treatment (MK-8189-012)
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: MK-8189
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and PK of Ascending Dosages of Moxidectin Versus Ivermectin Against Strongyloides Stercoralis
Status: UNKNOWN
Conditions: Strongyloides Stercoralis Infection
Interventions: DRUG: Moxidectin|DRUG: Ivermectin|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Adverse Events and Suspected Adverse Drug Reactions in Patients Under Apixaban for Prevention of Stroke and Systemic Embolism With Non-Valvular Atrial Fibrillation and Venous Thromboembolic Events in Patients Who Have Undergone Elective Hip or Knee Replacement Surgery
Status: WITHDRAWN
Conditions: Cerebral Stroke|Thrombosis, Deep Vein|Pulmonary Embolism
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Predictive Analytics and Computer Visualization Enhances Patient Safety to Prevent Falls
Status: NOT_YET_RECRUITING
Conditions: Falls and Falls With Injury
Interventions: OTHER: Fall prevention algorithm|OTHER: Inspiren camera visualization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mediterranean vs. High-Fermented-Food Diet Adherence on Inflammation in Lupus
Status: ACTIVE_NOT_RECRUITING
Conditions: Lupus Erythematosus, Systemic
Interventions: OTHER: Mediterranean Dietary Pattern|OTHER: High Fermented Food Dietary Pattern
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Antiemetic Agents in Orthognathic Surgery Patients
Status: COMPLETED
Conditions: Emesis, Postoperative|Maxillofacial Abnormalities
Interventions: DRUG: Intravenous drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Brivaracetam Efficacy and Safety Study in Subjects With Partial Onset Seizures
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Placebo|DRUG: Brivaracetam|DRUG: Brivaracetam|DRUG: Antiepileptic drugs with market authorization available per country
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dual Cyclooxygenase-2 and Carbonic Anhydrase Inhibition
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: CG100649 (2 mg)|DRUG: Celecoxib|DRUG: Placebo capsules|DRUG: Naproxen|DRUG: Acetazolamide|DRUG: CG100649 (8 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CO2 Field Saturating Alternative Techniques Comparison
Status: COMPLETED
Conditions: Embolism Air Post-Procedural
Interventions: BEHAVIORAL: NO CO2|DEVICE: CO2 Cannula|DEVICE: CO2 Cardia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Oral Cholecalciferol (Vitamin D3) on Bone Health, Neuromuscular Function, and Quality of Life in Adults With Chronic Kidney Disease
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DIETARY_SUPPLEMENT: cholecalciferol|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of CXD101 in Combination With Pembrolizumab for Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Status: WITHDRAWN
Conditions: Diffuse Large B Cell Lymphoma
Interventions: COMBINATION_PRODUCT: Pembrolizumab and CXD101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REal-World Analyses of Stroke - Thrombus Occlusion REtrieval
Status: RECRUITING
Conditions: Acute Ischemic Stroke|Vessel Occlusion|Stroke|Ischemic
Interventions: DEVICE: MicroVention Mechanical Thrombectomy Devices as first-line treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Atorvastatin on Biomarkers of Inflammation, Coagulopathy, Angiogenesis & T-cells
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: atorvastatin|DRUG: atorvastatin|DRUG: placebo for atorvastin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Vaccine for HIV
Status: COMPLETED
Conditions: HIV|Therapeutic Vaccine
Interventions: BIOLOGICAL: rVSV|BIOLOGICAL: IL-12 pDNA adjuvant|BIOLOGICAL: HIV-Mag pDNA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Understanding Reactions to Emotional Material in the Media During COVID-19 - Study 2
Status: COMPLETED
Conditions: Non-clinical Participants|Intrusive Memories
Interventions: BEHAVIORAL: Simple cognitive task intervention|BEHAVIORAL: Attention placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long Term Prophylactic Therapy of Congenital Long QT Syndrome Type III (LQT3) With Ranolazine
Status: UNKNOWN
Conditions: Long QT Syndrome Type 3
Interventions: DRUG: Ranolazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of QL1706 Combined With Chemotherapy in Advanced Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small-cell Lung Cancer
Interventions: DRUG: QL1706
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Global Postural Correction Exercises on Stress Urinary Incontinence During Pregnancy: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: OTHER: Kegel exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Distribution of Nutrient Derived Amino Acids
Status: COMPLETED
Conditions: Muscle Mass|Protein Intake|Diet Modification|Protein Synthesis|Protein Breakdown|Sarcopenia
Interventions: OTHER: Distribution pattern of dietary proteins (minced meat)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intrauterine Injection of Human Chorionic Gonadotropin Injection (hCG) Before Frozen Embryo Transfer on Cycle Outcomes
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: intrauterine injection of uhCG|DRUG: Placebo|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Dose-proportionality of Tapentadol (CG5503) in Healthy Japanese and Korean Male Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: tapentadol (CG5503) ER two 100-mg TRF|DRUG: tapentadol (CG5503) ER 50-mg TRF|DRUG: tapentadol (CG5503) ER 25-mg TRF|DRUG: tapentadol (CG5503) ER 100-mg TRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Maximizing the Impact of Neuroplasticity Using Transcranial Electrical Stimulation Study 1
Status: COMPLETED
Conditions: Transcranial Direct Current Stimulation|Healthy
Interventions: DEVICE: Transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biological Implications of the Overlapping Phenomenon Between Childhood Schizophrenia and Autism Spectrum Disorders-Heterogeneity Approach Rather Than Diagnostic Boundary
Status: ACTIVE_NOT_RECRUITING
Conditions: Schizophrenia|Autism Spectrum Disorder
Interventions: OTHER: Structural anatomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tolerability and Pharmacokinetics of M2ES in the Treatment of Advanced Solid Tumor
Status: COMPLETED
Conditions: Tolerability|Pharmacokinetics|Endostatin
Interventions: DRUG: PEDylated Recombinant Human Endostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Low-does Cervical Epidural Lidocaine Cause Transient Weakness?
Status: TERMINATED
Conditions: Cervical Radiculopathy
Interventions: PROCEDURE: cervical interlaminar with lidocaine|PROCEDURE: cervical interlaminar with normal saline|DRUG: Lidocaine|DRUG: Triamcinolone Acetonide|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: YpsoPump Occlusion Detection Algorithm: Collection of Real-world Data for In-silico Evaluation of a New Software Algorithm to Refine Occlusion Detection in Subjects With Type 1 Diabetes Using Continuous Subcutaneous Insulin Infusion
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: YpsoPump® insulin pump system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Modulating Neurocognitive Processes of Learning to Trust and Distrust in Aging
Status: NOT_YET_RECRUITING
Conditions: Aging|Cognitive Change|Neurocognitive Disorders, Mild
Interventions: BEHAVIORAL: Contingent rtfMRI neurofeedback training|BEHAVIORAL: Non-contingent/sham rtfMRI neurofeedback training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Online Lapse Management Intervention
Status: UNKNOWN
Conditions: Nicotine Dependence, Cigarettes
Interventions: OTHER: Endre: a digital smoking cessation counsellor|OTHER: Lapse management system triggered from web-page|OTHER: Lapse management system triggered by SMS-textmessage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Liposomal Doxorubicin and Trastuzumab in Treating Women With Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: pegylated liposomal doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Assessment of Measurement Variability Across Automated Biometry Devices
Status: COMPLETED
Conditions: Myopia
Interventions: DIAGNOSTIC_TEST: Orbscan II|DIAGNOSTIC_TEST: IOL Master 700|DIAGNOSTIC_TEST: IOL Master 500|DIAGNOSTIC_TEST: Atlas 9000|DIAGNOSTIC_TEST: Lenstar 900|DIAGNOSTIC_TEST: Pentacam|DIAGNOSTIC_TEST: iTrace|DIAGNOSTIC_TEST: Argos|DIAGNOSTIC_TEST: Manual caliper measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of Potential Drug-drug Interactions Between Faldaprevir and the Immunosuppressant Drugs Cyclosporine or Tacrolimus
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Faldaprevir|DRUG: Faldaprevir|DRUG: Cyclosporine|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Daily Consumption of a Novel Biscuit Enriched With Edible Mushrooms, on Intestinal Health-related Parameters
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Novel biscuit enriched with mushroom powder containing 3g of β-glucans|OTHER: Placebo biscuit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ondansetron for Pediatric Mild Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury|Brain Concussion
Interventions: DRUG: Ondansetron|DRUG: PLacebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ultrasound-guided Bilateral ESP Block and Wound Infiltration for Spinal Surgical Analgesia
Status: COMPLETED
Conditions: Pain, Postoperative|Spinal Disease|Anesthesia, Local|Anesthesia, Regional
Interventions: OTHER: Visual Analog Score|OTHER: patient satisfaction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Dendritic Cell-Based Therapeutic Vaccine Strategies for HIV Functional Cure
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections
Interventions: BIOLOGICAL: a1DC + inactivated whole autologous HIV|BIOLOGICAL: a1DC + conserved HIV peptides|BIOLOGICAL: a1DC + no antigen|BIOLOGICAL: pgDC + inactivated whole autologous HIV|BIOLOGICAL: pgDC + conserved HIV peptides|BIOLOGICAL: pgDC + no antigen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Probiotics to Treat End Stage Renal Disease
Status: COMPLETED
Conditions: Kidney Failure, Chronic
Interventions: DRUG: Bifid Triple Viable Capsules|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ovarian Hyperstimulation and Fibrin Clot Properties.
Status: UNKNOWN
Conditions: Fibrin Blood Clot|Infertility, Female|Endometriosis
Interventions: DIAGNOSTIC_TEST: fibrin clot properties
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Adjunctive Oral Systemic Vitamin E Therapy on Salivary Nitric Oxide Level in Patients With Erosive Oral Lichen Planus
Status: COMPLETED
Conditions: Lichen Planus
Interventions: DRUG: Topical corticosteroid and Vitamin E|DRUG: Topical corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Narrowband UVB Light Therapy to Patients With Dark Skin Types Who Have 10% of Their Body Involved With Psoriasis Vulgaris.
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DEVICE: Phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing Patient Satisfaction With LATISSE® for Increasing Eyelash Prominence
Status: COMPLETED
Conditions: Hypotrichosis
Interventions: DRUG: bimatoprost ophthalmic solution 0.03%|DRUG: bimatoprost vehicle solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Scars After Central Venous Catheters
Status: UNKNOWN
Conditions: Hypertrophic Scars|Keloids
Interventions: DRUG: Betamethason-17-valerate and fusidic acid|DRUG: Fusidic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: VOB560-MIK665 Combination First in Human Trial in Patients With Hematological Malignancies (Relapsed/Refractory Non-Hodgkin Lymphoma, Relapsed/Refractory Acute Myeloid Leukemia, or Relapsed/Refractory Multiple Myeloma)
Status: TERMINATED
Conditions: Non-Hodgkin Lymphoma (NHL)|Acute Myeloid Leukemia (AML)|Multiple Myeloma (MM)
Interventions: DRUG: VOB560|DRUG: MIK665
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Comparison of PARtial Wrist Fusion With or Without Triquetral Excision (PARTE)
Status: RECRUITING
Conditions: Wrist Arthritis|Wrist Arthropathy|Scapholunate Advanced Collapse|Scaphoid Nonunion|Post-traumatic; Arthrosis|Arthritis|Musculoskeletal Diseases|Joint Diseases
Interventions: PROCEDURE: Four-Corner Arthrodesis|PROCEDURE: Three-Corner or Capitolunate Arthrodesis with Triquetral Excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Rheumatoid Arthritis Study to Assess Early Response to Abatacept+MTX as Defined by Improvement of Synovitis Measures by Power Doppler Ultrasonography
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Abatacept|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Dairy and Non-Dairy Snacks on Food Intake, Subjective Appetite in Children
Status: COMPLETED
Conditions: Food|Eating|Appetite
Interventions: OTHER: Potato chips|OTHER: Greek yogurt|OTHER: Cookies|OTHER: Cheese|OTHER: Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sperm Micro-swim up Technique; Process and Select in the Same Dish: a Sibling-oocyte-split Design
Status: COMPLETED
Conditions: Assisted Reproductive Technology|Infertility
Interventions: PROCEDURE: Micro-swim up technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Mild Stimulation Protocol Using Clomiphene Citrate for Women With PCOS Undergoing in Vitro Fertilization
Status: ACTIVE_NOT_RECRUITING
Conditions: PCO - Polycystic Ovaries|Infertility
Interventions: DRUG: mild stimulation protocol: oral Clomiphene Citrate|DRUG: Conventional Stimulation Protocol: will receive FSH/HMG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality in the Operating Room
Status: COMPLETED
Conditions: Anesthesia, Intravenous|Pain, Postoperative|Delayed Recovery From Anesthesia|Satisfaction|Relaxation Therapy
Interventions: OTHER: Virtual Reality Immersive Relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Botox Treatment Into the Upper One Third of the Face an Area on Mood and Self -Appearance Satisfaction
Status: COMPLETED
Conditions: Mood
Interventions: DRUG: Botulinum Neurotoxin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Neoadjuvant Chemotherapy Combined With PD-1 Monoclonal Antibody in the Treatment of Operable Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Sintilimab + chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rasagiline (Azilect) - Neuroprotection for Macula-off Retinal Detachment
Status: TERMINATED
Conditions: Retinal Detachment
Interventions: DRUG: Rasagiline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Force of Endotracheal Tube Extubation; Esophagus vs. Trachea
Status: TERMINATED
Conditions: Intubation, Intratracheal
Interventions: DIAGNOSTIC_TEST: Measuring extubation force
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Olaparib and Durvalumab in Treating Participants With Metastatic Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Estrogen Receptor Negative|HER2/Neu Negative|Progesterone Receptor Negative|Prognostic Stage IV Breast Cancer AJCC v8|Triple-Negative Breast Carcinoma
Interventions: BIOLOGICAL: Durvalumab|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sildenafil for Treatment of Urinary Incontinence in Patients With Spinal Cord Injuries
Status: RECRUITING
Conditions: Spinal Cord Injuries|Urinary Incontinence
Interventions: DRUG: Sildenafil Citrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sight and Hearing Investigation Into Effects on Delirium
Status: ACTIVE_NOT_RECRUITING
Conditions: Hearing Loss|Hearing Loss, Age-Related|Hearing Disability|Delirium|Delirium in Old Age|Delirium of Mixed Origin|Delirium With Dementia|Delirium on Emergence|Delirium, Cause Unknown|Delirium Superimposed on Dementia|Delirium Confusional State|Delirium;Non Alcoholic|Hearing Loss, Bilateral|Hearing Loss, Sensorineural|Hearing Loss, Functional|Hearing Loss, High-Frequency|Hearing
Interventions: BEHAVIORAL: Communication Signage|BEHAVIORAL: Amplifier Use
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of Empagliflozin to Treat Prediabetes
Status: RECRUITING
Conditions: PreDiabetes|Prediabetic State|Overweight and Obesity
Interventions: DRUG: Empagliflozin|DRUG: Multivitamin-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Investigational Daily Disposable Multifocal Contact Lenses Produced With Different Manufacturing Processes in Myopes
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: senofilcon A C3|DEVICE: Dailies Total 1® Multifocal Contact Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Incidence of Postoperative Re-stratification for Recurrence in Well-differentiated Thyroid Cancer - A Single Tertiary Israeli Center Experience
Status: COMPLETED
Conditions: Well Differentiated Thyroid Carcinoma|Papillary Thyroid Cancer
Interventions: PROCEDURE: UNILATERAL THYROIDECTOMY
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ficus Septica Leaves Fraction as a Complementary Therapy for Stadium IV Breast Cancer Patients
Status: RECRUITING
Conditions: Breast Cancer Stage IV
Interventions: DIETARY_SUPPLEMENT: FADA (active fraction of Ficus septica leaf) 800 mg/day|DIETARY_SUPPLEMENT: FADA (active fraction of Ficus septica leaf) 2000 mg/day|OTHER: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: This Study Tests How BI 754111 is Distributed in Patients With Advanced Non-small Cell Lung Cancer or Patients With Head and Neck Cancer Who Are Treated With BI 754091
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung|Head and Neck Neoplasms
Interventions: DRUG: BI 754111|DRUG: [89Zr]Zr-BI 754111|DRUG: BI 754091
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Axon Therapy and Conventional Medical Management for Painful Diabetic Neuropathy Compared to Sham and Conventional Medical Management
Status: COMPLETED
Conditions: Neuralgia|Neuropathic Pain|Painful Diabetic Neuropathy
Interventions: DEVICE: Axon Therapy and CMM|DEVICE: Sham and CMM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Telehealth Pain Self-Management for Employed Adults
Status: COMPLETED
Conditions: Chronic Pain|Brain Injuries, Traumatic|Multiple Sclerosis|Spinal Cord Injuries|Amputation
Interventions: BEHAVIORAL: E-TIPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers for Ventilator-associated Pneumonia
Status: RECRUITING
Conditions: Pneumonia, Ventilator-Associated
Interventions: DIAGNOSTIC_TEST: Heparin-binding protein|DIAGNOSTIC_TEST: Interleukin-26|DIAGNOSTIC_TEST: Microbiome|DIAGNOSTIC_TEST: Bacterial transcriptome|DIAGNOSTIC_TEST: Proteome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of TAE+HAIC Combined With Camrelizumab and Apatinib in the Treatment of Advanced Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Gene-Activated® Human Glucocerebrosidase (GA-GCB) Enzyme Replacement Therapy in Gaucher Disease
Status: COMPLETED
Conditions: Gaucher Disease, Type 1
Interventions: BIOLOGICAL: VPRIV ®,
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Community-Effectiveness of the Distribution of Insecticide-Treated Bed Nets Through Social Marketing Antenatal Care Services in Malaria Control in Rural Burkina Faso
Status: COMPLETED
Conditions: Malaria
Interventions: PROCEDURE: ITN distribution channel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: ECT
Clinical trial: Assessing Effect of Withdrawal Time on Adenoma Detection Rate for Screening Colonoscopy
Status: TERMINATED
Conditions: Colon Cancer|Rectal Cancer|Colorectal Cancer
Interventions: PROCEDURE: Colonoscopy with 6 minute withdrawal|PROCEDURE: Colonoscopy 9 minute withdrawal|PROCEDURE: Colonoscopy 12 minute withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Online Dietary and Resistance Training to Improve Physical Function in Older Cancer Survivors, E-PROOF Trial
Status: RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Stage I Colorectal Cancer AJCC v8|Stage I Prostate Cancer AJCC v8|Stage II Colorectal Cancer AJCC v8|Stage II Prostate Cancer AJCC v8|Stage III Colorectal Cancer AJCC v8|Stage III Prostate Cancer AJCC v8
Interventions: OTHER: Exercise Intervention|OTHER: Informational Intervention|OTHER: Nutritional Assessment|OTHER: Physical Performance Testing|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Safety and Efficacy Study in Subjects With Diabetic Neuropathic Pain
Status: COMPLETED
Conditions: Diabetic Neuropathic Pain
Interventions: DRUG: ABT-894|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Tenecteplase in Covid-19 Diagnosed With Pulmonary Embolism
Status: TERMINATED
Conditions: Pulmonary Embolism|COVID
Interventions: DRUG: TNKase|DRUG: Placebo|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Local Intraoperative Steroid on Dysphagia After ACDF
Status: COMPLETED
Conditions: Dysphagia
Interventions: DRUG: Methylprednisolone|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Using Covered Stent of Diameter of 7mm in TIPS
Status: UNKNOWN
Conditions: Liver Disease
Interventions: DEVICE: the stent of diameter of 7mm|DEVICE: the stent of diameter of 8mm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Escitalopram in Adult Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Escitalopram|DRUG: Placebo|DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of Carbamazepine on the Pharmacokinetics of Paliperidone Extended Release (ER) in Patients With Schizophrenia or Bipolar I Disorder
Status: COMPLETED
Conditions: Schizophrenia|Bipolar Disorder
Interventions: DRUG: paliperidone ER; Carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid Urinary Tract Infection Diagnosis and Real-time Antimicrobial Stewardship Decision Support
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DIAGNOSTIC_TEST: Rapid diagnostics alone|OTHER: Real-time antimicrobial stewardship decision support
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: RPTR-168 in Patients With Human Papillomavirus Strain 16 (HPV-16) E6/E7 Positive Tumors and Melanoma
Status: TERMINATED
Conditions: Head and Neck Squamous Cell Carcinoma|Melanoma|Cervical Cancer
Interventions: BIOLOGICAL: RPTR-168
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Structured Diabetes Self-Management Education and Care Outcomes in Adults liVIng With Type 2 Diabetes in Accra, Ghana
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: DESMOND|OTHER: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Aesthetic Outcome of Electrodesiccation and Curettage vs Excision With Complex Linear Closure
Status: TERMINATED
Conditions: Cutaneous Surgery
Interventions: OTHER: Electrodesiccation and Curettage vs Excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: First Study of Secukinumab in Pre-filled Syringes in Subjects With Chronic Plaque-type Psoriasis: Response at 12 Weeks
Status: COMPLETED
Conditions: Moderate to Severe Plaque-type Psoriasis
Interventions: DRUG: secukinumab 150 mg|DRUG: secukinumab 300 mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Risk Reduction-Diet in Pregnancy - Follow up 20 Years After the "CARRDIP"-Trial
Status: RECRUITING
Conditions: Nutrition
Interventions: OTHER: Antiatherogenic diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: APOLO-Teens, a Web-based Intervention For Adolescents With Overweight/Obesity
Status: COMPLETED
Conditions: Pediatric Obesity
Interventions: BEHAVIORAL: APOLO-Teens web-based intervention|OTHER: Treatment as Usual for Pediatric Obesity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tailored Mediterranean Lifestyle Education in Patients With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: "ThinkMed" resource at baseline|BEHAVIORAL: Standard Care Control|BEHAVIORAL: "ThinkMed" resource (staged)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Spectacles Lens in Concussed Kids
Status: TERMINATED
Conditions: Concussion, Mild|Convergence Insufficiency|Accommodation; Insufficiency
Interventions: DEVICE: Glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cost-utility Analysis of the Use of the Paro Robotic Seal by Elderly Patients With Moderate or Severe Cognitive Disorders in Institutions: a Randomised Study.
Status: TERMINATED
Conditions: Cognitive Impairment
Interventions: OTHER: With robotic seal "PARO"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Remote Ischemic Preconditioning on Cardiac Function After Cardiac Surgery
Status: WITHDRAWN
Conditions: Atrial Fibrillation|Ventricular Arrythmias|Myocardial Injury|Cardiac Function
Interventions: PROCEDURE: Remote Ischemic Preconditioning|PROCEDURE: Control/sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lapatinib Plus Capecitabine Versus Trastuzumab Plus Capecitabine in ErbB2 (HER2) Positive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastases, Brain
Interventions: DRUG: capecitabine|DRUG: lapatinib|DRUG: trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Acetaminophen (ACM) in Post-operative Dental Pain
Status: COMPLETED
Conditions: Post Operative Dental Pain
Interventions: DRUG: acetaminophen Tablet|DRUG: acetaminophen Caplet|DRUG: ibuprofen Liquid-filled capsule|DRUG: Placebo Tablet|DRUG: Placebo Caplet|DRUG: Placebo Liquid-filled capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Efficacy of LT-02 in Patients With Mesalazine Refractory Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis|Large Intestine|Diarrhea|Abdominal Pain
Interventions: DRUG: LT-02|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase IIb Study for ALX-0061 Monotherapy in Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: ALX-0061|BIOLOGICAL: Placebo|BIOLOGICAL: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Feasibility of Thromboprophylaxis With Apixaban in JAK2-positive Myeloproliferative Neoplasm Patients
Status: COMPLETED
Conditions: Myeloproliferative Neoplasm (MPN)|Essential Thrombocythemia (ET)|JAK2 Mutation|Polycythemia Vera (PV)|Primary Myelofibrosis|Venous Thromboembolism (VTE)
Interventions: DRUG: Apixaban 2.5 MG Oral Tablet [ELIQUIS]|DRUG: Aspirin 81 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tumor Tissue, Blood Samples, and Family History in Predicting Tumor Development and Response to Treatment in Young Patients With Low-Grade Glioma
Status: UNKNOWN
Conditions: Brain and Central Nervous System Tumors
Interventions: OTHER: biologic sample preservation procedure|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of DOT Spectacles in Chinese Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Juvenile Myopia|Myopia
Interventions: DEVICE: Novel spectacle lens design|DEVICE: Spectacle lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of a Procedure for Managing Oral Anticoagulants (NACO) in the Management of Fractures
Status: COMPLETED
Conditions: Femur Fracture
Interventions: PROCEDURE: Standard Department procedure for managing direct-acting oral anticoagulants|PROCEDURE: New Department procedure for managing direct-acting oral anticoagulants
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunoevasive Tactics Employed by Myeloid Malignancy After Allogeneic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Relapse Leukemia|Allogeneic Stem Cell Transplantation|Immune Evasion, Tumor
Interventions: BIOLOGICAL: blood sample|BIOLOGICAL: bone marrow sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bevacizumab, Radiation Therapy, and Cisplatin in Treating Patients With Previously Untreated Locally Advanced Cervical Cancer
Status: COMPLETED
Conditions: Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Cervical Squamous Cell Carcinoma, Not Otherwise Specified|Stage IB Cervical Cancer AJCC v6 and v7|Stage IIA Cervical Cancer AJCC v7|Stage IIB Cervical Cancer AJCC v6 and v7|Stage III Cervical Cancer AJCC v6 and v7
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Cisplatin|RADIATION: External Beam Radiation Therapy|RADIATION: Internal Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breastfeeding and Oral Contraceptives: a Randomized, Controlled Trial
Status: COMPLETED
Conditions: Breast Feeding|Contraception
Interventions: DRUG: Combined estrogen-progestin pill|DRUG: Progestin-only pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluticasone Propionate/Salmeterol Combination 250/50 DISKUS in the Exercise Endurance Time in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: fluticasone propionate/salmeterol inhalation powder DISKUS 250/50|DRUG: tiotropium bromide inhalation powder HandiHaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trigger Point Injections and Pelvic Rehabilitation for the Treatment of Pelvic Floor Myalgia and Sexual Pain
Status: UNKNOWN
Conditions: Dyspareunia
Interventions: DRUG: Trigger Point Injections Triamcinolone Acetonide, Bupivacaine Hydrochloride|PROCEDURE: Pelvic Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Raltegravir + Lamivudine/Abacavir in HIV/Tuberculosis Co-Infected Patients
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: Raltegravir; Abacavir/Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment for Patients With Stage III or IV Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoblastic Lymphoma
Interventions: DRUG: Vincristine|PROCEDURE: Radiation Therapy|DRUG: Daunomycin|DRUG: L-Asparaginase|DRUG: Cytarabine|DRUG: Methotrexate|DRUG: Mercaptopurine|DRUG: Etoposide|DRUG: Cyclophosphamide|DRUG: Prednisone|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neonatal HIV Early Infant Diagnosis (EID) Versus Standard of Care EID- Long Term Impact on inFant hEalth (LIFE)
Status: COMPLETED
Conditions: HIV, Neonatal HIV Early-Infant-Diagnosis (EID), Point-of-Care Testing (PoC)
Interventions: OTHER: point-of care (PoC) neonatal HIV early infant diagnosis (EID)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Eye Drops for Early Morning-Associated Corneal Swelling of the Cornea
Status: COMPLETED
Conditions: Fuchs' Endothelial Dystrophy
Interventions: OTHER: Hyperosmolar eye drops|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Increasing Treatment Adherence in Co-Occurring Psychiatric and Drug Use Disorders
Status: COMPLETED
Conditions: Diagnosis, Dual (Psychiatry)|Psychiatric Diagnosis|Drug Use Disorders
Interventions: BEHAVIORAL: Adherence Feedback (AF)|BEHAVIORAL: AF + Contingency Management (AF + CM)|BEHAVIORAL: AF + Motivational Enhancement Therapy (AF + MET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: OTHER
Clinical trial: PEP-device for Treatment of Swimming-induced Pulmonary Edema (SIPE)
Status: RECRUITING
Conditions: Swimming Induced Pulmonary Edema (SIPE)|Pulmonary Edema|Lung Diseases
Interventions: DEVICE: PEP-device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigation Of The Absorption And Pharmacokinetics Of Multiple Doses Of Two Controlled Release Pregabalin Tablets As Compared To Multiple Doses Of The Immediate Release Pregabalin Capsule
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pregabalin controlled release, 165 mg|DRUG: Pregabalin controlled release, 330 mg|DRUG: Pregabalin immediate release, 150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ED90 of Norepinephrine and Phenylephrine Infusions Under Intensive Treatment in Preeclamptic Patients
Status: NOT_YET_RECRUITING
Conditions: Adverse Effect
Interventions: DRUG: Norepinephrine|DRUG: Phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT