pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: High Flow Nasal Cannula After Esophagectomy
Status: RECRUITING
Conditions: Esophageal Cancer|Postoperative Pulmonary Atelectasis|Postoperative Pneumonia|Postoperative Pneumothorax|Postoperative Infection of Incision|Postoperative Acute Myocardial Infarction
Interventions: DEVICE: AIRVO2|OTHER: STANDARD CARE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QUILT-3.051: NANT Ovarian Cancer Vaccine: Combination Immunotherapy in Subjects With Epithelial Ovarian Cancer Who Have Progressed on or After Standard-of-care (SoC) Therapy
Status: WITHDRAWN
Conditions: Ovarian Cancer
Interventions: BIOLOGICAL: Avelumab|BIOLOGICAL: Bevacizumab|DRUG: Capecitabine|DRUG: Cyclophosphamide|DRUG: 5-fluorouracil|DRUG: Fulvestrant|DRUG: Leucovorin|DRUG: Paclitaxel|DRUG: omega-3 acid ethyl esters|DRUG: Oxaliplatin|RADIATION: Stereotactic Body Radiation Therapy|BIOLOGICAL: ALT-803|BIOLOGICAL: ETBX-021|BIOLOGICAL: ETBX-051|BIOLOGICAL: ETBX-061|BIOLOGICAL: GI-4000|BIOLOGICAL: GI-6301|BIOLOGICAL: haNK®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioactive Glass (Sol-gel) for Alveolar Bone Regeneration After Surgical Extraction
Status: COMPLETED
Conditions: Bone Loss|Vertical Alveolar Bone Loss|Horizontal Alveolar Bone Loss
Interventions: OTHER: bioactive glass (sol-gel)|OTHER: empty extraction socket
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Perineal Wound Infection on the Anal Sphincter
Status: COMPLETED
Conditions: Obstetric Trauma|Perineum; Injury|Perineal Infection|Anal Sphincter Injury
Interventions: DIAGNOSTIC_TEST: Three-dimensional Endoanal Ultrasound|DIAGNOSTIC_TEST: Transperineal Ultrasound(multiplanar)|DIAGNOSTIC_TEST: The MolecuLight i:X: Bacterial autofluorescence camera|DEVICE: Silhouette® 3D camera: Three-dimensional wound measuring camera
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pfizer-BioNTech COVID-19 Vaccine Effectiveness Study - Kaiser Permanente Southern California
Status: RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: Primary Exposure Status of Pfizer-BioNTech COVID-19 Vaccine|BIOLOGICAL: BNT162b2 BA.4/5 bivalent|BIOLOGICAL: XBB.1.5-adapted vaccinated
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lopinavir/Ritonavir Monotherapy Versus Standard Highly Active Antiretroviral Therapy (HAART) in HIV/HCV Coinfected Patients Starting Treatment With Anti-Hepatitis C Virus (HCV) Therapy
Status: UNKNOWN
Conditions: HIV Infections|Hepatitis C
Interventions: DRUG: LPV/r|DRUG: PEG-IFNa 2a|DRUG: Ribavirin|DRUG: NUCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SGI-110 and Donor Lymphocyte Infusions (DLI) After Allogeneic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Myelodysplastic Syndromes|Acute Myeloid Leukemia
Interventions: DRUG: Guadecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Strength Training and Medication Effects in Parkinson Disease Effects on Hypokinesia in Parkinson Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Resistance Exercise via Negative Eccentric Work|BEHAVIORAL: Standard care exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase IB Study Of Oral SCH 66336 Preoperatively In Patients With Head And Neck Squamous Cell Cancer
Status: COMPLETED
Conditions: Carcinoma, Squamous Cell|Cancer of Head and Neck
Interventions: DRUG: SCH66336
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Intubation in Coronavirus Disease 19 With Level 3 PPE
Status: UNKNOWN
Conditions: Intubation Complication
Interventions: PROCEDURE: PPE Level 3 and Video Laryngoscope|PROCEDURE: PPE Level 3 and Direct Laryngoscope|PROCEDURE: PPE Level 2 and Direct Laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoplasmic Reticulum Stress and Resistance to Treatments in Ph-negative Myeloproliferative Neoplasms
Status: COMPLETED
Conditions: Polycythemia Vera|Essential Thrombocythemia
Interventions: BIOLOGICAL: RNA sample of total leukocytes before start of treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pocket Haematoma Prevention in Patients Who Required Implantation/Replacement of a Pacemaker or Implantable Cardiac Defibrillator. The PHP Study.
Status: COMPLETED
Conditions: Pacemaker Implantation|Pocket Hematoma and Bleeding|Antiplatelet Therapy or Oral Anticoagulants
Interventions: DRUG: tissucol|PROCEDURE: drainage system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label Trial of the Effect of Valacyclovir on Plasma HIV-1 Levels Among HIV-1 Seropositive and HSV-1/2 Seronegative Persons
Status: WITHDRAWN
Conditions: HIV|HIV Infections
Interventions: DRUG: Valacyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 2A Trial of EPI-743 for Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: EPI-743 400mg|DRUG: EPI-743 200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Radiation Therapy and Chemotherapy With or Without Nimotuzumab
Status: WITHDRAWN
Conditions: Carcinoma|Head and Neck Cancer
Interventions: RADIATION: Radiation Therapy|DRUG: Nimotuzumab|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CSD190301: A Study to Assess Elements of Abuse Liability for Two Dissolvable Nicotine Lozenge Tobacco Products
Status: COMPLETED
Conditions: Smoking|Tobacco Use|Tobacco Smoking
Interventions: OTHER: Product A|OTHER: Product B|OTHER: Product C|OTHER: Product D|OTHER: Product E|OTHER: Product F|OTHER: Product G|OTHER: Product H
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bowel Preparation and Prokinetics in Capsule Endoscopy
Status: UNKNOWN
Conditions: Small Bowel Disease|Gastrointestinal Hemorrhage|Refractory Anemia
Interventions: DRUG: Senna|DRUG: Citramag powder|DRUG: Metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: DIAGNOSTIC
Clinical trial: E-assisted Follow up Diagnosis of Post Operative Digestive Complications
Status: RECRUITING
Conditions: Post-operative Complications After Colorectal Surgery|Post-operative Complications After Gastric Surgery|Post-operative Complications After Bariatric Surgery
Interventions: DEVICE: E-assessed clinical and biological follow up|OTHER: Usual at home follow up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effects of Vitamin D3 Alone and in a Combination With Omega-3 on the Association of C-peptide With Glycemic Control
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: VD3|DIETARY_SUPPLEMENT: Omega-3FA|DIETARY_SUPPLEMENT: VD3 and Omega-3FA|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dexmedetomidine Supplemented Analgesia and Incidence of Postoperative Delirium
Status: COMPLETED
Conditions: Elderly|Surgery|Analgesia|Dexmedetomidine|Complication, Postoperative|Delirium
Interventions: DRUG: Dexmedetomidine supplemented morphine analgesia|DRUG: Morphine analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention Programme for Improvement of Well-being and Level of Participation in Adolescents With Enhanced Psychiatric Burden in the School Environment.
Status: NOT_YET_RECRUITING
Conditions: Blended-care Counselling|Digital and Mental Literacy Training|App STEPS
Interventions: OTHER: blinded-care counselling|OTHER: App STEPS|OTHER: digital and mental literacy training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of Intralymphatic Immunotherapy (ILIT) for House Dust Mite, Cat, and Dog Allergen in Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: BIOLOGICAL: Allergen extract
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Pilot Study of Internet-based Cognitive Behavioral Therapy (CBT) for Body Dysmorphic Disorder With Global Recruitment
Status: COMPLETED
Conditions: Body Dysmorphic Disorders
Interventions: BEHAVIORAL: I-CBT for Body Dysmorphic Disorder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MuscleCare™ Pain Relief Therapy vs. Voltaren® in the Relief of Trapezius Trigger Point Musculoskeletal Pain.
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: MuscleCare Topical Product|DRUG: Voltaren Topical|DRUG: Nivea, Topical Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Amlodipine on the Lipid Profile of Newly Diagnosed Hypertensive Patients
Status: COMPLETED
Conditions: Hypercholesterolemia|Hypertension|Cholesterol Deposition
Interventions: DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Maternal Vit D Supplements & Infant and Maternal Biomarkers & Outcomes in Southern Ethiopia
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Basal-bolus Therapy, Comparing Stepwise Addition of Insulin Aspart Versus Complete Basal-bolus Regimen
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin aspart|DRUG: insulin aspart|DRUG: insulin detemir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Analysis in Detection of Atrial Arrhythmia and ECG Quality in Three Different Insertable Cardiac Monitors
Status: UNKNOWN
Conditions: Arrhythmias, Cardiac
Interventions: DEVICE: Insertion of ILR device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of the Quantiferon®-TB GOLD (in Tube) Assay With Tuberculin Skin Testing for Detecting Latent Tuberculosis Infection in Patients With Chronic Liver Disease Being Evaluated for or Awaiting Liver Transplantation
Status: WITHDRAWN
Conditions: Chronic Liver Disease|TB
Interventions: PROCEDURE: collection of blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Effectiveness and Safety Study of PF-04383119 for the Treatment of Pain in Interstitial Cystitis
Status: COMPLETED
Conditions: Cystitis, Interstitial
Interventions: DRUG: PF-04383119|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RESPIMER® Netiflow® vs. Saline Solutions During Nasal Irrigation Following Bilateral Ethmoidectomy (Nasal Polyposis)
Status: COMPLETED
Conditions: Polyp of Ethmoidal Sinus|Surgery
Interventions: OTHER: A postoperative care after ethmoid sinus surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Deep Learning Method to Predict Difficult Laryngoscopy Using Cervical Spine X-ray Image
Status: UNKNOWN
Conditions: Thyroid|Surgery|Intubation; Difficult or Failed
Interventions: DIAGNOSTIC_TEST: A deep learning model for predicting a difficult laryngoscopy based on a cervical spine lateral X-ray image
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quality of Life in Patients With Rectal Cancer Receiving Total Mesorectal Excision With or Without Stoma
Status: TERMINATED
Conditions: Rectal Cancer
Interventions: BEHAVIORAL: Quality of Life Questionnaire for gastrointestinal tract|BEHAVIORAL: Quality of Life Questionnaire|BEHAVIORAL: Faecal Incontinence Score
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Acotiamide on Gastric Motility and Satiation in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Acotiamide|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effects of Electrical Stimulation and Vitamin D Supplementation on Bone Health Following Spinal Cord Injury.
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injury
Interventions: DEVICE: NMES|DRUG: Vitamin D|PROCEDURE: Passive movement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Dose Escalation, Single Dose Study to Assess Safety and Pharmacokinetics of BAX930 in Hereditary Thrombotic Thrombocytopenic Purpura (TTP)
Status: COMPLETED
Conditions: Hereditary Thrombotic Thrombocytopenic Purpura (TTP)
Interventions: DRUG: Recombinant ADAMTS13
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rasagiline as Add on to Dopamine Agonists in the Treatment of Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Rasagiline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Home-based Sensor System to Detect Health Decompensation in Elderly Patients With History of CHF or COPD
Status: RECRUITING
Conditions: COPD|Chronic Obstructive Pulmonary Disease|COPD Exacerbation|CHF|Congestive Heart Failure
Interventions: OTHER: Data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optimal Protein Dose Per Meal During Weight Loss in Perspective to Maintaining Muscle Mass
Status: COMPLETED
Conditions: Protein Metabolism
Interventions: OTHER: 15 g protein hypocaloric|OTHER: 35 g protein hypocaloric|OTHER: 60 g protein hypocaloric|OTHER: 35 g protein energy balance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: COMMunication and Education for the New CPAP Experience
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: BEHAVIORAL: Couple-oriented intervention|BEHAVIORAL: Patient-oriented intervention|DEVICE: Continuous positive airway pressure (CPAP)|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Oral Intake After Pancreaticoduodenectomy in the Age of ERAS
Status: UNKNOWN
Conditions: Periampullary Carcinoma Resectable|Pancreaticoduodenectomy
Interventions: PROCEDURE: early oral intake|PROCEDURE: jejunostomy tube feeding (JTF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Calcium and Vitamin D Supplements on Metabolic and Hormonal Disturbances in Polycystic Ovary Syndrome Patients
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Vitamin D Deficiency/Insufficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Calcium Carbonate|DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Demonstrate the Non-inferiority of Olmesartan Medoxomil Versus Candesartan Cilexetil in Reducing Blood B-type (or Brain) Natriuretic Peptide Levels at Week 24
Status: TERMINATED
Conditions: Chronic Heart Failure|High Blood B-type (or Brain) Natriuretic Peptide (BNP) Level
Interventions: DRUG: olmesartan medoxomil + candesartan cilexetil placebo|DRUG: olmesartan medoxomil placebo + candesartan cilexetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Maraviroc vs. Efavirenz on CD4/CD8 Ratio
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: DRUG: Maraviroc (UK-427,857) QD + Zidovudine/Lamivudine BID|DRUG: Efavirenz QD + Zidovudine/Lamivudine BID|DRUG: Maraviroc (UK-427,857) BID + Zidovudine/Lamivudine QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Biotene® on the Symptoms of Xerostomia and Mastication and Swallowing
Status: UNKNOWN
Conditions: Xerostomia|Hyposalivation
Interventions: DEVICE: Biotene® Oralbalance Moisturizing Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of EYP-1901 in Patients With Diabetic Macular Edema (DME)
Status: NOT_YET_RECRUITING
Conditions: Diabetic Macular Edema
Interventions: DRUG: EYP-1901|DRUG: Aflibercept 2Mg/0.05Ml Inj,Oph
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vestibular Rehabilitation for Dizziness in Hearing Impaired Children.
Status: COMPLETED
Conditions: HEARING IMPAIRED CHILDREN
Interventions: OTHER: Gaze stability exercises|OTHER: Brandt-Daroff Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vinorelbine With Trastuzumab Emtansine in Pre-Treated HER2-Positive Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: Vinorelbine|DRUG: Trastuzumab Emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autogenous Demineralized Dentin Graft Combined With Injectable PRF + Metronidazole Versus Autogenous Demineralized Dentin Graft Combined With Injectable PRF Versus Autogenous Demineralized Dentin Graft Alone for Alveolar Ridge Preservation
Status: NOT_YET_RECRUITING
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: Alveolar ridge preservation using autogenous demineralized dentin graft combined with injectable PRF loaded with metronidazole|PROCEDURE: Alveolar ridge preservation using autogenous demineralized dentin graft combined with injectable PRF|PROCEDURE: Alveolar ridge preservation using autogenous demineralized dentin graft alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Single-dose, Crossover Study of 4 Decitabine and Tetrahydrouridine (EPI01) Formulations in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Self-Care to Prevent Birth-Related Urinary Incontinence in Diverse Women
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: BEHAVIORAL: Usual Care|BEHAVIORAL: Bladder Health class
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Efficacy, Safety and Tolerability of a New Bowel Cleansing Preparation (BLI800) in Adult Subjects Undergoing Colonoscopy
Status: COMPLETED
Conditions: Diagnosis Disease
Interventions: DRUG: BLI800|DRUG: Fortrans®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Do Physiotherapy Techniques Improve Posture During Admission for a Chest Infection in Adults With Cystic Fibrosis?
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: OTHER: Physiotherapy Musculoskeletal Treatment|OTHER: Control group measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Investigating the Anabolic Response to Resistance Exercise After Critical Illness (ARTIST-2)
Status: COMPLETED
Conditions: Critical Illness|Muscle Loss
Interventions: PROCEDURE: Resistance exercise|DIETARY_SUPPLEMENT: Oral protein supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Bemnifosbuvir on Cardiac Repolarization in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteer Study
Interventions: DRUG: Bemnifosbuvir (BEM)|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Ectoin® Allergy Nasal Spray and Ectoin® Allergy Eye Drops Compared to Placebo
Status: COMPLETED
Conditions: Allergic Rhinitis|Allergic Conjunctivitis
Interventions: DEVICE: Ectoin® Allergy Nasal Spray and Ectoin® Allergy Eye Drops|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cotavance™ Paclitaxel-Coated Balloon Versus Uncoated Balloon Angioplasty for Treatment of In-stent Restenosis in SFA and Popliteal Arteries
Status: UNKNOWN
Conditions: Catherization
Interventions: DEVICE: balloon angiolplasty - drug coated balloon (Cotavance, Medrad Inc.)|DEVICE: drug coated balloon inflation (Cotavance, Medrad Inc.)|DEVICE: uncoated balloon (e.g. Admiral, Medtronic)|DEVICE: balloon inflation, drug coated balloon (Cotavance, Medrad Inc.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pemetrexed Disodium and Sorafenib Tosylate in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor
Interventions: DRUG: sorafenib tosylate|DRUG: pemetrexed disodium|OTHER: laboratory biomarker analysis|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Ilaprazole on Ulcer Healing Rate and Prevention of Gastrointestinal Bleeding in the Patients Undergone ESD.
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Ilaprazole|DRUG: Rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Preventive Treatments for Talquetamab-related Oral Toxicity
Status: NOT_YET_RECRUITING
Conditions: Relapse Multiple Myeloma|Refractory Multiple Myeloma
Interventions: DRUG: Talquetamab|DRUG: Prophylaxis A|DRUG: Prophylaxis B|DRUG: Prophylaxis C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Integrative and Complementary Practice in Health as a Strategy in Obesity Treatment
Status: UNKNOWN
Conditions: Obesity|Weight Loss
Interventions: OTHER: Control Group|OTHER: Auriculotherapy Group|OTHER: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Insulin Sensitivity and Beta Cell Function After Carbohydrate Loading in Hip Replacement Surgery
Status: COMPLETED
Conditions: Insulin Sensitivity
Interventions: DIETARY_SUPPLEMENT: Experimental: PreOp, NutriciaNordica AB|DIETARY_SUPPLEMENT: Placebo Comparator: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evolution of a Novel Optical Coherence Tomography Based Index in Diagnosing Keratoconus
Status: RECRUITING
Conditions: Scansys, Pentacam, Keratoconus, Subclinical Keratoconus
Interventions: OTHER: Pentacam, Corvis ST and CASIA2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison Study of LMX4 Cream Versus J-Tip Needle-Free Injection System With Lidocaine for In-Office PAT for Clubfoot
Status: ACTIVE_NOT_RECRUITING
Conditions: Clubfoot
Interventions: DEVICE: J-Tip with Xylocaine MPF with placebo cream|DRUG: L.M.X.4 cream with J-Tip saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Evaluate the Lipid Effects of TRIA-662
Status: COMPLETED
Conditions: Hypertriglyceridemia|Mixed Hyperlipidemia
Interventions: DRUG: TRIA-662|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trans-Abdominal Fetal Pulse Oximetry - EFS-IDE
Status: RECRUITING
Conditions: Fetal Hypoxia|Fetal Distress|Fetal Conditions|Fetal Complications|Labor Fetal Anoxia|Labor (Obstetrics)--Complications|Oxygen Deficiency
Interventions: DEVICE: Fetal Oxygenation Measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: GANGlion Stellate Block for Treatment of Electric storRm (GANGSTER Trial)
Status: RECRUITING
Conditions: Ventricular Arrythmia|Ventricular Tachycardia|Ventricular Fibrillation|Arrhythmic Storm|Block
Interventions: PROCEDURE: Left ganglion stellate block|PROCEDURE: Sham left ganglion stellate block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraosseous Versus Intravenous Vascular Access During Resuscitation Following Out-of-Hospital Cardiac Arrest
Status: UNKNOWN
Conditions: Out-of-Hospital Cardiac Arrest
Interventions: DEVICE: EZ-IO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Pembrolizumab in Combination With Chemotherapy and Radiotherapy in Stage III NSCLC (KEYNOTE-799, MK-3475-799)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Pembrolizumab 200 mg|DRUG: Paclitaxel 45 mg/m^2|DRUG: Carboplatin AUC6|DRUG: Cisplatin 75 mg/m^2|DRUG: Pemetrexed 500 mg/m^2|RADIATION: Thoracic Radiation Therapy (TRT)|DRUG: Paclitaxel 200 mg/m^2|DRUG: Carboplatin AUC2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ADVM-022 Intravitreal Gene Therapy for Wet AMD
Status: COMPLETED
Conditions: Wet Age-related Macular Degeneration|Neovascular Age-related Macular Degeneration
Interventions: BIOLOGICAL: ADVM-022
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conventional Mechanical Ventilation and High Frequency Percussive Ventilation: Comparison of Their Effects on Alveolar Recruitment and Distension by CT-scan in Early ARDS Patients
Status: UNKNOWN
Conditions: ARDS
Interventions: DEVICE: High frequency percussive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Evaluation of the Application Procedure on the Antimicrobial Effects of 2 Antiseptics
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Chlorhexidine gluconate|DRUG: Povidone iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Statin for Preventing Hepatocellular Carcinoma Recurrence After Curative Treatment
Status: RECRUITING
Conditions: HepatoCellular Carcinoma
Interventions: DRUG: Atorvastatin|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Examine MPI SPECT Imaging With BMS068645 and Adenosine Compared to Coronary Angiography
Status: TERMINATED
Conditions: Heart Disease|Ischemic Heart Disease
Interventions: DRUG: apadenoson
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Impact of Almond Nut Consumption on Markers of CVD & Metabolic Health
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Almonds|DIETARY_SUPPLEMENT: Muffins/Crackers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: SupporTive Care At Home Research for Patients With Advanced Cancer (STAHR-cancer)
Status: RECRUITING
Conditions: Malignant Neoplasm|Home Care Services|Quality of LIfe|Unplanned Hospitalization
Interventions: OTHER: Home-based care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Palmitoylethanolamide on Inner Retinal Function in Glaucoma Patients by Pattern Electroretinogram
Status: COMPLETED
Conditions: Glaucoma
Interventions: DIETARY_SUPPLEMENT: palmitoylethanolamide (PEA) 600 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study to Assess the Gingivitis and Plaque Effects of Various Dentifrices
Status: COMPLETED
Conditions: Gingivitis
Interventions: DRUG: 0.76% Sodium Monofluorophosphate Dentifrice|DRUG: 0.454% Stannous Fluoride Dentifrice|DRUG: 0.454% Stannous Fluoride Dentifrice|DRUG: 0.454% Stannous Fluoride Dentifrice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Treatment (TMS) in Unipolar Depression
Status: COMPLETED
Conditions: Unipolar Depression
Interventions: PROCEDURE: Transcranial Magnetic Stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tshireletso: Safety, Efficacy and Feasibility of Cabotegravir-LA PrEP in a Breastfeeding Population in Botswana
Status: RECRUITING
Conditions: Pre-Exposure Prophylaxis (PrEP)|Breast Feeding
Interventions: DRUG: Cabotegravir Injection [Apretude]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Impact of the SMART ANGEL ™ Device on Follow-up at Home Following Major or Intermediate Outpatient Surgery
Status: UNKNOWN
Conditions: Ambulatory Surgery
Interventions: OTHER: Smart Angel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cysteamine for Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Cysteamine Bitartrate|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BIA Guided-fluid Management in Postinjury Open Abdomen
Status: COMPLETED
Conditions: Damage Control|Trauma Abdomen|Acute Compartment Syndrome
Interventions: OTHER: BIA-guided fluid resuscitation protocol|OTHER: Traditional fluid resuscitation protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of BEGEDINA® vs "Conventional Treatment" for Treating Steroid-Resistant Acute GvHD
Status: TERMINATED
Conditions: Graft vs Host Disease
Interventions: BIOLOGICAL: Begelomab|BIOLOGICAL: Conventional Second-line Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy Of Rivaroxaban and Ticagrelor for Patients With Atrial Fibrillation After Percutaneous Coronary Intervention
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation|Acute Coronary Syndrome
Interventions: DRUG: Ticagrelor|DRUG: Rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cost-Utility Analysis of Management of Peri Operative Haemorrhage Following Cardiac Surgery With Cardiopulmonary Bypass
Status: COMPLETED
Conditions: C.Surgical Procedure; Cardiac|Blood Transfusion|Blood Coagulation Disorders|Bypass, Cardiopulmonary|Hemostatic
Interventions: DEVICE: Thrombo-elastometry POC testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Potatoes on Markers of Cardiometabolic Health
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Potato-based side dish|DIETARY_SUPPLEMENT: Refined grain-based
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of Strontium +/- Cisplatin for the Palliation of Bone Pain Secondary to Hormone Refractory Prostate Cancer
Status: COMPLETED
Conditions: Hormone Refractory Prostate Cancer|Bone Metastases
Interventions: DRUG: strontium-89|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Macronutrient Effects on Alzheimer's Disease (MEAL-2)
Status: COMPLETED
Conditions: Prediabetic State|Insulin Resistance|Middle Age|Prehypertension|Mild Cognitive Impairment
Interventions: OTHER: Low Diet|OTHER: High Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High Sodium Diet and External Abdominal Compression in POTS
Status: TERMINATED
Conditions: Postural Orthostatic Tachycardia Syndrome
Interventions: DEVICE: External automated abdominal binder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: IDEA-033 Three Months Dose Finding in OA Followed by IDEA-033 Three Months Extension in OA
Status: COMPLETED
Conditions: Osteoarthritis; Knee
Interventions: DRUG: IDEA-033 (and rescue medication)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Front Line Pembrolizumab and Valemetostat in PD-L1 Positive, HPV-Negative Recurrent/Metastatic Squamous Cell Carcinoma (SCC) of the Head and Neck: The PANTHERAS
Status: NOT_YET_RECRUITING
Conditions: Sinonasal Cancer|Squamous Non-small Cell Lung Cancer|Lung Cancer|Head and Neck Squamous Cell Carcinoma|Head and Neck Carcnimona|Head and Neck Cancer
Interventions: DRUG: pembrolizumab|DRUG: valemetostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postmarketing Surveillance Study of Anticholinergics - Prescribing Pattern and Therapeutic Long Term Value in Patients Suffering From Moderate or Severe Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Atrovent®|DRUG: Ventilat®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Therapy in Patients With Localized Pancreatic Ductal Adenocarcinoma
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: RADIATION: Stereotactic body radiotherapy (SBRT)|DRUG: Zimberelimab|DRUG: Quemliclustat|DRUG: Etrumadenant|DRUG: Modified FOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy, Safety and Pharmacokinetic of Antiplatelet Therapy for Vicagrel
Status: COMPLETED
Conditions: Coronary Artery Disease|Percutaneous Coronary Intervention|Platelet Aggregation Inhibitors
Interventions: DRUG: Vicagrel 5mg|DRUG: Vicagrel 6mg|DRUG: Vicagrel 7.5mg|DRUG: Clopidogrel 75mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of PegIntron Plus Rebetol in Subjects With Chronic Hepatitis C Not Responding to Pegasys (Study P03833)
Status: TERMINATED
Conditions: Hepatitis C, Chronic
Interventions: BIOLOGICAL: PegIntron (peginterferon alfa-2b)|DRUG: Rebetol (ribavirin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Amitriptyline to Lifestyle Modification as Intervention for Vestibular Migraine
Status: ENROLLING_BY_INVITATION
Conditions: Vestibular Migraine
Interventions: DRUG: Amitriptyline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short and Long-Term Effectiveness of Existing Insomnia Therapies for Patients Undergoing Hemodialysis
Status: COMPLETED
Conditions: Insomnia|End Stage Renal Disease
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia|DRUG: Trazodone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intervening Early: Key Adolescent Outcomes
Status: ENROLLING_BY_INVITATION
Conditions: Depressive Symptoms|Conduct Disorder|Anxiety Disorders
Interventions: BEHAVIORAL: Attachment and Biobehavioral Catch-up (ABC)|BEHAVIORAL: Developmental Education for Families (DEF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Observational Study to Evalute the Efficacy and Safety of Avastin (Bevacizumab) in Addition to Platinum-Based Chemotherapy for First-Line Treatment of Participants With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Bevacizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Efficacy and Safety of Tralokinumab in Patients With Active, Moderate-to-severe Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: tralokinumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study on 18F-DCFPyL PET/CT Imaging in Biochemical Recurrence of Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer Recurrent
Interventions: DIAGNOSTIC_TEST: DCFPyL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Learning Enhancement Through Neurostimulation in Autism
Status: COMPLETED
Conditions: Autism
Interventions: DEVICE: Active Transcranial Direct Current Stimulation|DEVICE: Sham Transcranial Direct Current Stimulation|BEHAVIORAL: PEERS Social Skills Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: D-Cycloserine Enhancement of Exposure in Social Phobia
Status: COMPLETED
Conditions: Social Anxiety Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Group Therapy (CBGT)|DRUG: D-Cycloserine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of Compound Danshen Dripping Pills to Treat Diabetic Retinopathy
Status: UNKNOWN
Conditions: Non-proliferative Diabetic Retinopathy
Interventions: DRUG: Compound danshen dripping pills|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The MOVI-HIIT Pilot Trial: The Impact of Activity Breaks on Cognitive Function, Adiposity and Fitness in Preschoolers
Status: COMPLETED
Conditions: Physical Activity|Obesity, Childhood|Cardiovascular Diseases|High Intensity Interval Training|Cognition
Interventions: BEHAVIORAL: MOVI-HIIT intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Haemo-autologous Antegrade Repriming (HAR) as Minimum Impact Perfusion Strategy for Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Anemia|Cognitive; Disorder, Due to General Medical Condition|Embolism, Air|Transfusion|Cardiac Disease|Extracorporeal Circulation; Complications|Valve Anomalies
Interventions: PROCEDURE: HAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Airtraq Versus MacIntosh Intubation Via Nasal Approach
Status: UNKNOWN
Conditions: Tracheal Intubation
Interventions: DEVICE: Intubation|DEVICE: Airtraq
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect on Glucose Control of AC2993 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent
Interventions: DRUG: AC2993|DRUG: AC2993|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Medically Ill Hospitalized Patients for COVID-19 THrombosis Extended ProphyLaxis With Rivaroxaban ThErapy: The MICHELLE Trial
Status: COMPLETED
Conditions: Covid19|Venous Thromboembolism
Interventions: DRUG: Rivaroxaban 10 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Safety and Efficacy of Standard Intravenous Immunoglobulins in Pregnant Women With Primary Cytomegalovirus Infection
Status: UNKNOWN
Conditions: Cytomegalovirus Congenital Infection
Interventions: BIOLOGICAL: standard intravenous immunoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of NGR-hTNF Versus Placebo as Maintenance Treatment in Patients With Advanced MPM
Status: COMPLETED
Conditions: Advanced Malignant Pleural Mesothelioma
Interventions: DRUG: NGR-hTNF|DRUG: Placebo|OTHER: Best Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of FOLFIRI Association Treatment in Patients 70 Years of Age and Older With Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Irinotecan associated to fluorouracil and leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing the CYPHER® ELITE™ to the CYPHER® Bx VELOCITY® Sirolimus-Eluting Stent Systems
Status: UNKNOWN
Conditions: Coronary Artery Disease|Coronary Atherosclerosis
Interventions: DEVICE: CYPHER® ELITE™ Sirolimus-Eluting Stent System|DEVICE: CYPHER® Bx VELOCITY® Sirolimus-eluting Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improvement of Compliance for High Doses of EPA Amongst Patients With Colorectal Cancer
Status: COMPLETED
Conditions: Compliance|Abdominal Cancer
Interventions: DIETARY_SUPPLEMENT: Möllers Omega-3 Ekstra Sterk|DIETARY_SUPPLEMENT: Nutrifriend Cachexia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE