pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pevonedistat, Azacitidine, Fludarabine Phosphate, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Recurrent Acute Myeloid Leukemia|Recurrent Myelodysplastic Syndrome|Refractory Acute Myeloid Leukemia|Refractory Myelodysplastic Syndrome
Interventions: DRUG: Azacitidine|DRUG: Cytarabine|DRUG: Fludarabine Phosphate|DRUG: Methotrexate|DRUG: Pevonedistat|DRUG: Therapeutic Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Adjuvant Radiotherapy for Resected Head and Neck Cancers
Status: RECRUITING
Conditions: Resectable Head and Neck Squamous Cell Carcinoma
Interventions: RADIATION: 42 Gy Radiation Therapy|RADIATION: 39 Gy Radiation Therapy|RADIATION: 32.5 Gy Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Neuroendocrine Effects of Pioglitazone in Patients With Cancer and Cachexia
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Pioglitazone 45 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate Vadadustat for the Correction of Anemia in Participants With Non-dialysis-dependent Chronic Kidney Disease
Status: COMPLETED
Conditions: Anemia|Non-Dialysis-Dependent Chronic Kidney Disease
Interventions: DRUG: Vadadustat|DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Stem Cell Transplantation in Children and Adolescents With Acute Lymphoblastic Leukaemia
Status: UNKNOWN
Conditions: Lymphoblastic Leukemia, Acute, Childhood;
Interventions: DRUG: VP16|RADIATION: TBI|DRUG: VP16, ATG|RADIATION: TBI|DRUG: Fludarabine, OKT3, Treosulfan, Thiotepa|DRUG: VP16, ATG|RADIATION: TBI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Carbonated Soft Drinks on the Body Weight
Status: COMPLETED
Conditions: Obesity|Metabolic; Complications|Dietary Habits
Interventions: OTHER: Sugar-sweetened soft drink|OTHER: Aspartame-sweetened soft drink|OTHER: Semi-skimmed milk|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Infliximab or Vedolizumab in Treating Immune Checkpoint Inhibitor-Related Colitis in Patients With Genitourinary Cancer or Melanoma
Status: RECRUITING
Conditions: Colitis|Lung Non-Small Cell Carcinoma|Malignant Genitourinary System Neoplasm|Malignant Solid Neoplasm|Melanoma
Interventions: BIOLOGICAL: Infliximab|BIOLOGICAL: Vedolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Comparative Study Evaluating the Tolerability and Efficacy of Two Topical Therapies for the Treatment of Keloids and Hypertrophic Scars
Status: COMPLETED
Conditions: Keloid|Hypertrophic Scar|Cicatrix, Hypertrophic
Interventions: DRUG: 0.5% hydrocortisone, silicone, vitamin E lotion|DRUG: Onion extract gel|DRUG: Cetearyl alcohol lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ACHN-975 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: ACHN-975|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Efficacy of LB1148 for Subjects Undergoing Elective Bowel Resection
Status: COMPLETED
Conditions: Adhesions|Ileus
Interventions: DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of Clarithromycin in Mustard-Induced Bronchiolitis
Status: COMPLETED
Conditions: Bronchiolitis Obliterans|Acute Obliterating Bronchiolitis
Interventions: DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Sputum Cytometry Analysis in Lung Cancer Screening After Professional Asbestos Exposure
Status: UNKNOWN
Conditions: Lung Neoplasms
Interventions: OTHER: low-dose CT-scan AND induced sputum sample AND blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Study of Gastrointestinal Emptying Time in Adult Participants With Migraine Before and After Start of a mAb CGRP Antagonist
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Galcanezumab|DRUG: Erenumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Expectancy Challenge Alcohol Literacy Curriculum on Reducing College Student Alcohol Use and Harms
Status: ENROLLING_BY_INVITATION
Conditions: Alcohol Use, Underage|Harmful; Use, Alcohol
Interventions: BEHAVIORAL: ECALC|BEHAVIORAL: ECALC Plus Weekly Boosters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Study of Atherosclerosis With Ramipril and Rosiglitazone
Status: COMPLETED
Conditions: Atherosclerosis|Impaired Glucose Tolerance|Isolated Impaired Fasting Glucose|Cardiovascular Disease
Interventions: DRUG: Ramipril|DRUG: Rosiglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: DAISe 1 Feasibility Study to Evaluate the DAISe Thrombectomy System for Acute Ischemic Stroke
Status: TERMINATED
Conditions: Acute Ischemic Stroke
Interventions: DEVICE: DAISe Thrombectomy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incomplete Response in Late Life Depression: Getting to Remission (IRL GREY)
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: venlafaxine XR plus aripiprazole|DRUG: venlafaxine plus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Adalimumab Plus Medium Dose Oral Glucocorticosteroid for Refractory Behçet's Uveitis
Status: NOT_YET_RECRUITING
Conditions: Uveitis
Interventions: DRUG: Adalimumab plus different doses of oral glucocorticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D Supplementation on Testosterone Level in Women With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: PCOS|Vitamin D
Interventions: DRUG: Vitamin D3|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Japanese Single and Multiple Ascending Dose (JSMAD), Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) Study of AZD5069
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD5069|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 1b Study to Assess Safety, Tolerability, and Pharmacokinetics of ARCT-810 in Stable Adult Subjects With Ornithine Transcarbamylase Deficiency
Status: COMPLETED
Conditions: Ornithine Transcarbamylase Deficiency
Interventions: BIOLOGICAL: ARCT-810|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Intubation Conditions Between the Gliderite and the S-Guide
Status: COMPLETED
Conditions: Nasal Obstruction|Lumbar Stenosis, Familial
Interventions: DEVICE: Tracheal intubation with Gliderite|DEVICE: Tracheal intubation with S-guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Papillary Balloon Dilation Versus Intraductal Lithotripsy
Status: RECRUITING
Conditions: Choledocholithiasis
Interventions: PROCEDURE: Initial therapy with papillary balloon dilation|PROCEDURE: Initial therapy with intraductal lithotripsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Nab-paclitaxel Plus Camrelizumab and S-1 Conversion Therapy for Gastric Cancer With Positive Exfoliative Cancer Cells
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Camrelizumab Nab-Paclitaxel S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Rebamipide 2% Ophthalmic Suspension in Subjects With Dry Eye - Effects on Central Cornea
Status: COMPLETED
Conditions: Keratoconjunctivitis Sicca|Dry Eye
Interventions: DRUG: rebamipide 2% ophthalmic suspension|DRUG: placebo eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of YH32367 in Patients With HER2 Positive Locally Advanced or Metastatic Solid Tumor
Status: RECRUITING
Conditions: HER2-Positive Solid Tumor
Interventions: DRUG: YH32367
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasonography for Fluid Assessment in Parturients With Preeclampsia Undergoing Cesarean Section
Status: COMPLETED
Conditions: Elective Cesarean Section|Preeclampsia
Interventions: PROCEDURE: Spinal Anesthesia|DRUG: Intrathecal Bupivacaine|DRUG: Intrathecal Fentanyl|PROCEDURE: Cesarean Delivery|RADIATION: lung ultrasound scans|OTHER: Ultrasound Assessment of the Inferior Vena Cava|OTHER: Optic nerve sheath diameter|DRUG: ringer acetate|DRUG: Intravenous Ephedrine|DRUG: Intravenous Syntocinon
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Safety and Efficacy of a Novel Accelerated Partial Breast Irradiation Regimen
Status: RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: IMRT/VMAT-Based Accelerated Partial Breast Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifileucel With Reduced Dose Fludarabine/Cyclophosphamide Lymphodepletion and Interleukin-2 for the Treatment of Patients With Unresectable or Metastatic Melanoma
Status: RECRUITING
Conditions: Clinical Stage IV Cutaneous Melanoma AJCC v8|Metastatic Melanoma|Pathologic Stage IIIC Cutaneous Melanoma AJCC v8|Unresectable Melanoma
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Cyclophosphamide|PROCEDURE: Echocardiography|DRUG: Fludarabine|BIOLOGICAL: Interleukin-2|BIOLOGICAL: Lifileucel|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Multigated Acquisition Scan|PROCEDURE: Tumor Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mandible and Sub-mandible Using the 1440nm Wavelength Laser and Hand Piece
Status: COMPLETED
Conditions: Skin Tightening of the Mandibular and Sub-mandibular Areas
Interventions: DEVICE: 1440 nm wavelength laser with handpiece (Cynosure)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Fish Oil Supplementation in Gastrointestinal Cancer
Status: UNKNOWN
Conditions: Gastrointestinal Cancer|Colorectal Cancer|Stomach Cancer
Interventions: DIETARY_SUPPLEMENT: Encapsuled fish oil|DIETARY_SUPPLEMENT: Encapsulated Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FOLFOXIRI Plus Panitumumab in Metastatic RAS Wild-type, Left-sided Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody Therapy in Treating Women With Locally Advanced or Metastatic Breast Cancer Previously Treated With Combination Chemotherapy
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: BIOLOGICAL: monoclonal antibody HuHMFG1
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Fasting for Pancreatitis
Status: NOT_YET_RECRUITING
Conditions: Pancreatitis|Pancreatitis, Acute|Pancreatitis, Chronic|Pancreas Disease|Acute Recurrent Pancreatitis
Interventions: OTHER: Intermittent Fasting|OTHER: No intermittent fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Chemotherapy With Aspirin in Patients With Breast Cancer After Neoadjuvant Chemotherapy
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Cyclophosphamide and Methotrexate and Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Dose Response Study of Levalbuterol in the Prevention of Exercise Induced Bronchoconstriction Compared to Racemic Albuterol in Pediatric Subjects
Status: COMPLETED
Conditions: Asthma|Bronchoconstriction
Interventions: DRUG: Levalbuterol HFA MDI|DRUG: Racemic Albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of High-Dose B-Complex Vitamins on the Symptoms of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DIETARY_SUPPLEMENT: Capsule with folate, Vitamin B12 & pyridoxine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Armodafinil for Fatigue in Sarcoidosis
Status: COMPLETED
Conditions: Sarcoidosis|Fatigue|Sleepiness
Interventions: DRUG: Armodafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-HIV Drugs for Ugandan Patients With HIV and Tuberculosis
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: Abacavir|DRUG: Lamivudine|DRUG: Zidovudine|DRUG: Tuberculosis treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Getting Physical on Cigarettes - Smoking Cessation & Relapse Prevention
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: Exercise Behaviour Maintenance|BEHAVIORAL: Smoking Relapse prevention booklets|BEHAVIORAL: Contact control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Theory-Based Education on Patient Empowerment and Self-Efficacy in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabete Type 2
Interventions: BEHAVIORAL: Application of The Theory of Planned Behaviour for Diabetes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Physica System KR vs Physica System CR (K-20)
Status: UNKNOWN
Conditions: Total Knee Replacement
Interventions: DEVICE: Physica Kinematic Retaining knee replacement|DEVICE: Physica Cruciate Retaining knee replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT of Follow up Following Cataract Extraction
Status: UNKNOWN
Conditions: Cataract
Interventions: OTHER: No Clinical Follow up|OTHER: Quality of Life questionnaire|OTHER: Patient satisfaction Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase IV:Safety and Efficacy of EMSAM in Adolescents With Major Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Selegiline Transdermal System|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Moxifloxacin Versus Amoxicillin Clavulanic Acid in Treatment of Acute Exacerbation of Chronic Bronchitis
Status: COMPLETED
Conditions: Chronic Bronchitis
Interventions: DRUG: Avelox (Moxifloxacin, BAY12-8039)|DRUG: Amoxicillin clavulanic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Belantamab Mafodotin, Bortezomib and Dexamethasone Versus Daratumumab, Bortezomib and Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Belantamab mafodotin|DRUG: Daratumumab|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Oral Salmon Calcitonin in Patients With Knee Osteoarthritis (OA 2 Study)
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: DRUG: Oral Salmon Calcitonin|DRUG: Oral Salmon Calcitonin (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peanut Oral Immunotherapy Study of Early Intervention for Desensitization
Status: COMPLETED
Conditions: Peanut Allergy
Interventions: BIOLOGICAL: AR101 powder provided in capsules & sachets|BIOLOGICAL: Placebo powder provided in capsules & sachets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial on Outpatients With Systemic Sclerosis Treated With Well-Being Therapy or With a Control Therapy
Status: COMPLETED
Conditions: Systemic Sclerosis
Interventions: BEHAVIORAL: Well-Being Therapy|BEHAVIORAL: Control condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Effect of MK0476 With Concomitant Administration of and Removal of Inhaled Beclomethasone in Asthmatic Patients (0476-029)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: montelukast sodium|DRUG: beclomethasone|DRUG: Placebo inhaler|DRUG: placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Computerized HIV/Sexually Transmitted Disease (STD) Prevention Program
Status: COMPLETED
Conditions: Acquired Immunodeficiency Syndrome|HIV Infections
Interventions: BEHAVIORAL: Tailored Information Program for Safer Sex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Therapy of Icotinib in Epidermal Growth Factor Receptor Mutated NSCLC Patients
Status: UNKNOWN
Conditions: Non-small-cell Lung Cancer
Interventions: DRUG: Icotinib|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Boron Neutron Capture Therapy (BNCT) Combined With Cetuximab in the Treatment of Locally Recurred Head and Neck Cancer
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: RADIATION: BNCT|DRUG: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rational Drug Use in Elderly People
Status: NOT_YET_RECRUITING
Conditions: Rational Drug Use
Interventions: BEHAVIORAL: Education|OTHER: Rational Drug Use Guide|OTHER: Medicine Box|BEHAVIORAL: Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Epidural Labor Analgesia With Dexmedetomidine or Sufentanil
Status: UNKNOWN
Conditions: Pharmacological Action
Interventions: DRUG: Dexmedetomidine ropivacaine|DRUG: No analgesia labor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimized Treatment Algorithm for Patients With Early Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Adalimumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Increased Physical Activity on Adolescents' Health and Academic Performance: The School in Motion Study
Status: COMPLETED
Conditions: Physical Activity|Academic Achievement|Mental Health
Interventions: BEHAVIORAL: Physical education|BEHAVIORAL: Physical active learning|BEHAVIORAL: Physical activity|BEHAVIORAL: Be happy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating Denosumab on Vascular and Bone Metabolism in Osteoporotic Chronic Kidney Disease (HDENOBS)
Status: NOT_YET_RECRUITING
Conditions: Osteoporosis|Chronic Kidney Disease 5D
Interventions: PROCEDURE: MDCT (multidetector computed tomography)|PROCEDURE: Dual-energy X-ray absorptiometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diquafosol vs Hyaluronic Acid for Diabetic Dry Eye
Status: NOT_YET_RECRUITING
Conditions: Diabetic Eye Problems
Interventions: DRUG: 3% Diquafosol tetrasodium|DRUG: 0.1% hyaluronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I-II Study on Stereotactic Body Radiotherapy in 3 Fractions for Low/Int Risk Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: RADIATION: stereotactic body radiotherapy SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of 90-day Oral Testosterone Therapy in Chinese Males With Type 2 Diabetes (T2DM)
Status: TERMINATED
Conditions: Assess the Effects of a the 90-day Oral TS Study Regimen on PSA, IPSS, Haemoglobin and Haematocrit, and to Assess Adverse and Serious Adverse Events.
Interventions: DRUG: Andriol Testocaps
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SIMIDIS: Azacitidine and Beta Erythropoietin Treatment in Patients With Myelodysplastic Syndrome
Status: TERMINATED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: Azacitidine|DRUG: Beta Erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Guselkumab for the Treatment of Participants With New-onset or Relapsing Giant Cell Arteritis
Status: TERMINATED
Conditions: Giant Cell Arteritis
Interventions: DRUG: Guselkumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Steroids in the Treatment of Nephrotic Syndrome Relapse
Status: UNKNOWN
Conditions: Glomerular Disease
Interventions: DRUG: prednisone 60 mg/meter square Body Surface Area|DRUG: prednisone 45 mg|DRUG: prednisone 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Paclitaxel (Genexol®) and Cisplatin Versus Paclitaxel Loaded Polymeric Micelle (Genexol-PM®) and Cisplatin in Advanced Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Paclitaxel (Genexol®)|DRUG: Paclitaxel loaded polymeric micelle (Genexol-PM®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the ENSEAL® X1 Curved Jaw Tissue Sealer and Generator G11 in Thoracic, Urologic, and Ear, Nose, and Throat (ENT) Procedures
Status: COMPLETED
Conditions: Thoracic Procedure|Urologic Procedure|Ear, Nose and Throat Procedure
Interventions: DEVICE: ENSEAL X1 Curved Jaw Tissue Sealer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conventional vs Digital CAD/CAM Splints for Bruxism
Status: NOT_YET_RECRUITING
Conditions: Bruxism
Interventions: DEVICE: Digital occlusal splints (CAD/CAM)|DEVICE: Conventional occlusal splints
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Food Supplementation With Diuripres for Blood Pressure Modulation in Subjects With High-Normal Blood Pressure
Status: COMPLETED
Conditions: High-Normal Blood Pressure
Interventions: DIETARY_SUPPLEMENT: Dietary Supplement|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: L-citrulline to Improve Adverse Outcomes in Admitted Children (EChiLiBRiST, Clinical Trial 2, Inpatients)
Status: NOT_YET_RECRUITING
Conditions: Infectious Disease|Infections|Child, Only
Interventions: DIETARY_SUPPLEMENT: L-citrulline|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Oral Immunotherapy for Cow's Milk Allergy in School-aged Children
Status: COMPLETED
Conditions: Milk Allergy|Anaphylaxis
Interventions: DIETARY_SUPPLEMENT: milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Alpha Linolenic Acid Intake on Patients With Elevated Glycemic Status
Status: UNKNOWN
Conditions: Elevated Blood Sugar
Interventions: DIETARY_SUPPLEMENT: Flaxseed oil capsule|DIETARY_SUPPLEMENT: Corn oil capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tissue Adhaesive in Wound Closure Following Primary Total Knee Arthroplasty
Status: COMPLETED
Conditions: Total Knee Arthroplasty|Infection|Arthroplasty Complications
Interventions: DEVICE: tissue adhesive (Leukosan®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Selinexor in Relapsed or Refractory Peripheral T-cell Lymphoma or Cutaneous T-cell Lymphoma
Status: TERMINATED
Conditions: Peripheral T-cell Lymphoma (PTCL)|Cutaneous T-cell Lymphoma (CTCL)
Interventions: DRUG: Selinexor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Palovarotene to Treat Preosseous Flare-ups in FOP Subjects
Status: COMPLETED
Conditions: Fibrodysplasia Ossificans Progressiva
Interventions: DRUG: Palovarotene|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Haemostasis and Tranexamic Acid in Caesarean Delivery
Status: COMPLETED
Conditions: Postpartum Hemorrhage|Hyperfibrinolysis
Interventions: DIAGNOSTIC_TEST: peripartum haemostasis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of a Transdiagnostic Mobile App Intervention Among University Students
Status: COMPLETED
Conditions: Emotion Regulation|Stress|Resilience|Depressive Symptoms|Anxiety
Interventions: BEHAVIORAL: Mobile Transdiagnostic Emotion Regulation Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Compare Upadacitinib (ABT-494) to Placebo in Adults With Rheumatoid Arthritis on Stable Dose of Conventional Synthetic Disease-Modifying Antirheumatic Drugs (csDMARDs) With an Inadequate Response or Intolerance to Biologic DMARDs
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Placebo|DRUG: Upadacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dry Mouth Toothpaste Study - Comparing Two Toothpastes With Arginine
Status: RECRUITING
Conditions: Xerostomia
Interventions: DEVICE: 8% Arginine toothpaste|DRUG: 1000 ppm F toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Diagnosis and Clinical Management of Familial Hypercholesterolemia Through Integrated Machine Learning, Implementation Science, and Behavioral Economics
Status: ENROLLING_BY_INVITATION
Conditions: Familial Hypercholesterolemia
Interventions: BEHAVIORAL: Testing centralized referral mechanisms for PCPs|BEHAVIORAL: Testing out patient outreach methods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Percutaneous Electroneurostimulation of Dermatome T6 for Appetite Reduction and Weight Loss in Morbidly Obese Patients
Status: COMPLETED
Conditions: Appetite Reduction|Weight Loss
Interventions: PROCEDURE: Percutaneous electroneurostimulation of dermatome T6|BEHAVIORAL: Diet 1200 Kcal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiological Outcomes of Medacta Shoulder System
Status: RECRUITING
Conditions: Primary Osteoarthritis|Secondary Osteoarthritis|Rotator Cuff Tear Arthropathy|Rheumatoid Arthritis Shoulder|Avascular Necrosis|Fracture|Revision of Shoulder Arthroplasty
Interventions: DEVICE: Medacta Shoulder System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tolerability and Pharmacokinetics of CSPCHA115 Capsules in Chinese Healthy Volunteers
Status: COMPLETED
Conditions: Asthma; Allergic Rhinitis
Interventions: DRUG: CSPCHA115 100 mg; Matching placebo 100 mg|DRUG: CSPCHA115 200 mg; Matching placebo 200 mg|DRUG: CSPCHA115 400 mg; Matching placebo 400 mg|DRUG: CSPCHA115 600 mg; Matching placebo 600 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel,Carboplatin,Trastuzumab and Bevacizumab for Breast Cancer and Bone Marrow Micrometastases
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: bevacizumab|BIOLOGICAL: trastuzumab|DRUG: carboplatin|DRUG: docetaxel|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga-PSMA-11 PET/CT in Imaging Patients With Intermediate or High Risk Prostate Cancer Before Surgery
Status: COMPLETED
Conditions: Prostate Adenocarcinoma|Stage IIB Prostate Cancer AJCC v7|Stage III Prostate Cancer AJCC v7|Stage IV Prostate Cancer AJCC v7
Interventions: PROCEDURE: Computed Tomography|RADIATION: Gallium Ga 68 Gozetotide|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Exercise and Inhibition of Dipeptidyl Peptidase-4 on Insulin Secretion in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus Type 1
Interventions: DRUG: Sitagliptin|DRUG: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three Dimensional Digital Preoperative Planning for the Osteosynthesis of Distal Radius Fractures
Status: RECRUITING
Conditions: Distal Radius Fracture
Interventions: PROCEDURE: Preoperative planning|PROCEDURE: Osteosynthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrating Palliative Care Education in Pulmonary Rehabilitation
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease|Interstitial Lung Disease
Interventions: OTHER: Pulmonary rehabilitation integrating education about palliative care|OTHER: Pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Observe the Benefit of Adding Brachytherapy After CCRT on Resectable Esophageal Cancer Patients Without Surgery
Status: RECRUITING
Conditions: Esophageal Cancer
Interventions: RADIATION: Add-on Brachytherapy|DEVICE: "BRAXX" Esophageal Brachytherapy Applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Register Studying the therApeutic Patient Population With Multifocal Atherosclerosis
Status: COMPLETED
Conditions: Polyvascular Disease|Atherosclerosis|Atherosclerosis Generalized|Cardiovascular Diseases|Cardiac Death|Chronic Kidney Diseases|Bleeding|Acute Stroke|Acute Coronary Syndrome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inducibility and Stability of Ventricular Tachycardia Inpatients Undergoing VT Ablation Under General Anesthesia
Status: COMPLETED
Conditions: Ventricular Tachycardia
Interventions: DRUG: Versed|DRUG: Fentanyl|DRUG: Propofol|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fasting Study of Clopidogrel Bisulfate Tablets 75 mg to Plavix® Tablets 75 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Clopidogrel Bisulfate Tablets 75 mg|DRUG: Plavix® Tablets 75 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bioequivalence of Vildagliptin Tablet Manufactured in China Compared to Imported Vildagliptin Tablet in Chinese Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Vildagliptin (LAF237)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study Evaluating the Medullary Thyroid Cancer Management's Care Using PET F-DOPA in Patients With a High Level of Postoperative Residual Thyrocalcitonin
Status: COMPLETED
Conditions: Medullary Thyroid Cancer
Interventions: OTHER: 18F-DOPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Simulation-Based Mastery Learning for Thoracentesis to Improve Outcomes
Status: COMPLETED
Conditions: Misadventure During Thoracentesis
Interventions: OTHER: Simulation-based mastery learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of a Psychological Intervention in Patients Undergoing Total Knee Arthroplasty
Status: TERMINATED
Conditions: Knee Arthroplasty, Total
Interventions: OTHER: PNE+HyP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The CAMPUS Project: Cholinergic Augmentation of Cognitive Deficits in Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: donepezil (5-10 mg/day)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TPF Concurrent Chemo-radiotherapy Plus Immunotherapy for Local Advanced Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efavirenz and Ritonavir on Human Brain P-Glycoprotein
Status: COMPLETED
Conditions: Drug Effects
Interventions: DRUG: [11C] desmethyl-loperamide|OTHER: Control - no pretreatment|DRUG: Oral ritonavir|DRUG: Oral efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study Using Two Oral Chemotherapy Agents for Chronic Lymphocytic Leukemia
Status: WITHDRAWN
Conditions: Chronic Lymphocytic Leukemia|Leukemia
Interventions: DRUG: dasatinib and lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization of Systemic Treatment Strategies in Elderly Patients With Advanced Solid Malignancies
Status: COMPLETED
Conditions: Colorectum Advanced Malignancies|Breast Advanced Malignancies|Prostate Advanced Malignancies
Interventions: PROCEDURE: venapunction|PROCEDURE: bone marrow punction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Non Interventional Study to Monitor the Safety and Effectiveness of Trajenta (Linagliptin, 5 mg, q.d) in Korean Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Trajenta tablet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Compare S-217622 With Placebo in Non-Hospitalized Participants With COVID-19
Status: COMPLETED
Conditions: SARS-CoV-2 Infection
Interventions: DRUG: S-217622|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 4-Week, Multi-Center, Randomized, Db-Blind, Placebo-Controlled, Dose-Ranging Study for the IBS-C in Pts. 6 to <12 Yrs
Status: RECRUITING
Conditions: Irritable Bowel Syndrome With Constipation (IBS-C)
Interventions: DRUG: Tenapanor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of IC14 in Acute Respiratory Distress Syndrome
Status: WITHDRAWN
Conditions: Acute Respiratory Distress Syndrome
Interventions: DRUG: IC14|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Pharmacokinetics of Trappsol and Effects on Potential Biomarkers of Niemann-Pick C1 (NPC1)
Status: COMPLETED
Conditions: Niemann-Pick Disease, Type C1
Interventions: DRUG: Hydroxypropyl-beta-cyclodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: High-Dose Quinapril Versus Low-Dose Quinapril Plus Amlodipine in the Treatment of High-Risk Hypertensive Patients
Status: TERMINATED
Conditions: Hypertension
Interventions: DRUG: Quinapril 40 mg|DRUG: Quinapril 10 mg and amlodipine 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Buteyko Breathing Technique Versus Incentive Spirometer on Breath Holding Time, Cardiopulmonary Endurance and Quality of Life in Patients With Post Lung Tumor Resection
Status: UNKNOWN
Conditions: Lung Tumor Resuction
Interventions: OTHER: Buteyko Breathing Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Venetoclax Plus Inotuzumab for B-ALL
Status: RECRUITING
Conditions: B-cell Acute Lymphoblastic Leukemia|B-Cell Lymphoma|ALL
Interventions: DRUG: Venetoclax|DRUG: Dexamethasone|DRUG: Inotuzumab Ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate Antihyperlipidemic Effect of a Classical Unani Antiobesity Formulation
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: safoof e muhazzil|DRUG: compressed tablet of safoof e muhazzil|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Booster Dose of PoliorixTM Vaccine in Previously Vaccinated Toddlers
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: PoliorixTM|BIOLOGICAL: Infanrix+Hib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Basiliximab in Calcineurin Inhibitor Intolerant Long-term Kidney Transplant Recipients Treated With Mycophenolic Acid and Steroids
Status: COMPLETED
Conditions: Kidney Transplantation|Adverse Effects
Interventions: DRUG: basiliximab|DRUG: MMF/EC-MPS|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 1 Study To Evaluate The Effect Of Dimebon On The Pharmacokinetics Of Dextromethorphan
Status: COMPLETED
Conditions: Huntington Disease|Alzheimer Disease
Interventions: DRUG: Dextromethorphan|DRUG: Dimebon + Dextromethorphan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination Chemotherapy and Total-Body Irradiation Followed by Peripheral Stem Cell or Bone Marrow Transplantation in Treating Patients With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: cyclosporine|DRUG: cytarabine|DRUG: fludarabine phosphate|DRUG: methotrexate|DRUG: mycophenolate mofetil|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Evaluation of Nalmefene Administered Intranasally to Healthy Volunteers
Status: COMPLETED
Conditions: Opioid-Related Disorders
Interventions: DRUG: Nalmefene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Adjuvant Chemotherapy With Cisplatin Followed by UFT in Serosa-positive Gastric Cancer (JCOG9206-2)
Status: COMPLETED
Conditions: Gastric Neoplasm
Interventions: PROCEDURE: Gastrectomy with D2 or greater lymph node dissection|DRUG: Gastrectomy+ chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influenza Vaccine and Pneumococcal Vaccine
Status: COMPLETED
Conditions: Influenza, Human|Pneumococcal Infections
Interventions: BIOLOGICAL: Influenza vaccination with PPV23|BIOLOGICAL: Influenza vaccination with PCV13
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of 2 Different Indomethacin Dosing Protocols to Treat Infants Delivered at <28 Weeks Gestation With a Persistent Patent Ductus Arteriosus
Status: COMPLETED
Conditions: Patent Ductus Arteriosus
Interventions: DRUG: indomethacin (two different dosing regimens)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Single Dose Study of ALZ-801 Prototype Tablets
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: ALZ-801 170 mg Fasting|DRUG: ALZ-801 205 mg Fasting|DRUG: ALZ-801 205 mg After Food|DRUG: ALZ-801 342 mg Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT