pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Short-term Existential Behavioural Therapy for Informal Caregivers of Palliative Patients: a Randomised Controlled Trial
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: EBT|BEHAVIORAL: treatment-as-usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Characterize Lung Deposition, Pharmacokinetics, Safety and Tolerability of Single Inhalations of Radiolabeled Ciprofloxacin Dry Powder in Healthy Subjects and Patients With Chronic Lung Diseases
Status: COMPLETED
Conditions: Respiratory System
Interventions: DRUG: Ciprofloxacin (Cipro Inhale, BAYQ3939)|DRUG: Ciprofloxacin (Cipro Inhale, BAYQ3939)|DRUG: Ciprofloxacin (Cipro Inhale, BAYQ3939)|DRUG: Ciprofloxacin (Cipro Inhale, BAYQ3939)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Energy Technique and Mulligan's Mobilization in Breast Cancer Surgery Patients
Status: RECRUITING
Conditions: Mobility Limitation|Muscle Relaxation|Kinematics|Postural; Defect|Breast Cancer
Interventions: OTHER: combination of mobilization with movement and muscle energy techniques|OTHER: muscle energy techniques Interventions:|OTHER: mobilization with movement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Phase 2 Study to Evaluate Efficacy and Safety of Oral Abexinostat as Monotherapy in Patients With Relapsed or Refractory Follicular Lymphoma
Status: RECRUITING
Conditions: Lymphoma, Follicular
Interventions: DRUG: Abexinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypertension Intervention to Reduce Osteonecrosis in Children With Acute Lymphoblastic Leukemia/Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension|Osteonecrosis|Osteonecrosis Due to Drug
Interventions: DRUG: Intensive Antihypertensive Therapy|DRUG: Conventional Antihypertensive Therapy|OTHER: Symptom Survey|OTHER: Semi-structured interview
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Prophylaxis for PEG in Children
Status: UNKNOWN
Conditions: Infection
Interventions: DRUG: co-amoxiclav|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cardiorespiratory Parameters and Glycated Hemoglobin of Patients With Type 2 Diabetes After a Rehabilitation Program
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Rehabilitation|Respiratory Therapy
Interventions: OTHER: Cardiovascular Rehabilitation|OTHER: Initial and Final assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prognostic Biomarkers in Patients With Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Adenocarcinoma|Recurrent Uterine Corpus Carcinoma|Stage I Uterine Corpus Cancer|Stage II Uterine Corpus Cancer|Stage III Uterine Corpus Cancer|Stage IV Uterine Corpus Cancer
Interventions: OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Efficacy and Safety Study of Desloratadine (MK-4117) in Japanese Participants With Chronic Urticaria (MK-4117-201)
Status: COMPLETED
Conditions: Urticaria
Interventions: DRUG: Desloratadine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Cross-sectional Study Evaluating the Sociodemographic and Clinical Characteristics of Patients Diagnosed With NVAF With a Risk of Stroke or Systemic Embolism, Who Are on Treatment to Adequately Control Their Coagulation and Treated in Primary Care Centres
Status: COMPLETED
Conditions: Stroke|Prevention and Control|Atrial Fibrillation
Interventions: DRUG: Direct Oral Anticoagulant (DOAC)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Homologous Recombination Deficiency Status in Epithelial Ovarian Cancer
Status: UNKNOWN
Conditions: Epithelial Ovarian Cancer|Chinese|Homologous Recombination Deficiency|BRCA1 Mutation|BRCA2 Mutation|Prognosis
Interventions: DIAGNOSTIC_TEST: Genomic testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Burosumab (KRN23) in Adults With Tumor-Induced Osteomalacia (TIO) or Epidermal Nevus Syndrome (ENS)
Status: COMPLETED
Conditions: Tumor Induced Osteomalacia (TIO)|Epidermal Nevus Syndrome (ENS)
Interventions: BIOLOGICAL: Burosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conventional Fasting Versus Lipid/Carbohydrate Infusion for Coronary Bypass Patients
Status: COMPLETED
Conditions: Metabolism Disorder
Interventions: DIETARY_SUPPLEMENT: G group|DIETARY_SUPPLEMENT: group L|DIETARY_SUPPLEMENT: Group C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Backup With Combivir or Single Dose (SD) Truvada in Order to Avoid Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI) Resistance After SD Nevirapine for the Prevention of Mother-to-child Transmission (PMTCT)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine and Lamivudine (Combivir)|DRUG: Emtricitabine and Tenofovir (Truvada)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Reliability of Consumer Sleep Trackers in Patients Suffering From Obstructive Sleep Apnea Syndrome
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DEVICE: Jawbone sleep tracker|DEVICE: Withings sleep tracker|DEVICE: BodyMedia Sense Wear accelerometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Efficiency of Autologous Platelet Gel (Platelet Rich Fibrin) Obtained From Own Patients' Blood Versus Vaselitulle in Dupuytren's Disease Postoperative Wound Healing
Status: COMPLETED
Conditions: Dupuytren's Contracture
Interventions: BIOLOGICAL: Autologous platelets gel|DEVICE: Vaselitulle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Placebo-Controlled Trial of Armodafinil (Nuvigil) for Fatigue in Patients With Malignant Gliomas
Status: COMPLETED
Conditions: Malignant Glioma
Interventions: DRUG: Armodafinil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized, Active-controlled, Double-blind, Parallel-Goup Study of the Efficacy and Safety of Extended Release(ER) Paliperidone in the Treatment of Schizophrenia
Status: COMPLETED
Conditions: Acute Schizophrenia
Interventions: DRUG: ER OROS paliperidone and Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Trial of an E-Health Intervention To Support Diabetes Care in Minority Youth (3Ms)
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: BEHAVIORAL: The 3Ms Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oat Processing on Gastric Emptying and Satiety Induced After Consuming Porridge
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: OTHER: Flaked oats|OTHER: Milled oats
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Heated Humidification System Breathing Circuit for Maintenance of Body Temperature in Pediatric Patients
Status: RECRUITING
Conditions: Temperature Change, Body
Interventions: DEVICE: Anapod™ Humi-Therm Heated Humidification System Breathing Circuit|DEVICE: Bair Hugger™ Warming Blanket
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluating a Brief Negotiational Intervention for Alcohol Use Among Injury Patients in Tanzania
Status: COMPLETED
Conditions: Alcohol Use
Interventions: BEHAVIORAL: Brief Negotiational Intervention|BEHAVIORAL: Standard Booster|BEHAVIORAL: Personalized Booster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Healing Effects of Rebamipide and Omeprazole in Helicobacter Pylori-positive Gastric Ulcer After Eradication Therapy
Status: COMPLETED
Conditions: Stomach Ulcer
Interventions: DRUG: Rebamipide|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Myelofibrosis
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders
Interventions: BIOLOGICAL: filgrastim|DRUG: busulfan|DRUG: cytarabine|DRUG: idarubicin|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effects of E-Mobile Education and Counselling Services on Bariatric Surgery Patients
Status: COMPLETED
Conditions: Bariatric Surgery|Counselling|Patient Education|Mobile Application
Interventions: OTHER: E-Mobile Education and Counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Impact of Oral Vitamin C in Prevention for Post Operative Atrial Fibrillation (POAF) in Coronary Artery Bypass Surgery (CABG) Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Post Operative Atrial Fibrillation
Interventions: DRUG: Vitamin C 500 MG Oral Capsule(High dose 2g daily)|DRUG: Vitamin C 500 MG Oral Capsule(Low-dose 1g daily)|DRUG: placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Comparing the Clinical Effects of Posterior Approach Versus Lateral Approach in Osteoarthritis Patients With a THA
Status: COMPLETED
Conditions: Unilateral Primary Osteoarthritis of Hip
Interventions: PROCEDURE: Total hip arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 52-Week Open-Label Safety Study of PD 0332334 in Subjects With Generalized Anxiety Disorder (GAD)
Status: TERMINATED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: PD 0332334
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capsule Endomicroscopy for Visualization of the Small Intestine in EED Population in Pakistan
Status: ENROLLING_BY_INVITATION
Conditions: Environmental Enteric Dysfunction
Interventions: DEVICE: Tethered Capsule Endomicroscope/Trans Nasal Endomicroscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Alpha Radiation Emitters Device for the Treatment of Newly Diagnosed Breast Carcinoma Patients With Distant Metastases
Status: TERMINATED
Conditions: Breast Carcinoma|Metastatic Breast Cancer|Invasive Breast Cancer|Distant Metastases.Pathology
Interventions: DEVICE: Device: Radiation: Diffusing Alpha Radiation Emitters Therapy (DaRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nerve Burial for Preventing Neuralgia After Total Knee Arthroplasty
Status: TERMINATED
Conditions: Neuralgia|Osteoarthritis of the Knee
Interventions: PROCEDURE: Total knee arthroplasty with Saphenous nerve burial|PROCEDURE: Standard total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Implantoplasty as Adjunct to Combined Surgical Therapy of Peri-Implantitis
Status: RECRUITING
Conditions: Peri-Implantitis
Interventions: PROCEDURE: Implantoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stylet Use for McGrath Videolaryngoscope
Status: COMPLETED
Conditions: Orotracheal Intubation
Interventions: DEVICE: McGrath videolaryngoscope|DEVICE: McGrath videolaryngoscope with Intubating stylet (Mallinckrodt)|DRUG: rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Shockwave Therapy and Platelet Rich Plasma for the Treatment of Erectile Dysfunction
Status: ACTIVE_NOT_RECRUITING
Conditions: Erectile Dysfunction
Interventions: DEVICE: Shock Wave therapy (SWT)|DRUG: Platelet Rich Plasma (PRP)|OTHER: Sham SWT|OTHER: Placebo Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib as Neoadjuvant Therapy in Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Ibrutinib|PROCEDURE: Radical prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genioglossus Muscle Training for Snoring and Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Snoring|Sleep Apnea, Obstructive
Interventions: DEVICE: Genioglossis Strength Trainer|DEVICE: Placebo Genioglossis Strength Trainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Study of Efficacy and Safety of Grazoprevir (MK-5172)/Elbasvir (MK-8742) Combination Regimen for Treatment-Naïve Participants With Chronic Hepatitis C Virus Genotypes 1, 4, and 6 (MK-5172-060)
Status: COMPLETED
Conditions: Chronic Hepatitis C Virus
Interventions: DRUG: Grazoprevir 100mg / Elbasvir 50 mg FDC|DRUG: Placebo to Grazoprevir / Elbasvir 50 mg FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GC1118 in Recurrent Glioblastoma Patients With High EGFR Amplification
Status: COMPLETED
Conditions: Glioblastoma, Adult|EGFR Amplification
Interventions: DRUG: GC1118
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Doses of BI 10773 Tablets
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: BI 10773 Placebo|DRUG: BI 10773|DRUG: BI 10773 Placebo|DRUG: BI 10773|DRUG: BI 10773 Placebo|DRUG: BI 10773 Placebo|DRUG: BI 10773|DRUG: BI 10773
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pelvic Drains After Radical Hysterectomy in Treating Patients With Uterine, Cervical, or Vaginal Cancer
Status: COMPLETED
Conditions: Cervical Cancer|Endometrial Cancer|Infection|Perioperative/Postoperative Complications|Vaginal Cancer
Interventions: PROCEDURE: infection prophylaxis and management|PROCEDURE: management of therapy complications|PROCEDURE: surgical procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Which Factors Influence the Outcome After Anatomical and Reverse Shoulder Arthroplasty?
Status: RECRUITING
Conditions: Arthroplasty, Replacement, Shoulder
Interventions: PROCEDURE: Early mobilization|PROCEDURE: Delayed mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Hyperlipidemia or Mixed Dyslipidemia at Risk of Cardiovascular Events
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: Bococizumab (PF-04950615; RN316)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Posaconazole Prophylaxis in Patients Receiving Hematopoietic Stem Cell Allograft (Allo-HSC) at High Risk of Invasive Fungal Infection (IFI)
Status: NOT_YET_RECRUITING
Conditions: Hematologic Malignancy
Interventions: DRUG: Posaconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carmustine in Treating Adults With Recurrent Supratentorial Low-Grade Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: carmustine|DRUG: polifeprosan 20 with carmustine implant|PROCEDURE: surgical procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Adoptive Tumor-infiltrating Lymphocyte Transfer With Nivolumab for Melanoma
Status: COMPLETED
Conditions: Advanced Melanoma
Interventions: DRUG: Combination of TIL Transfer with anti-PD-1 Therapy and low dose IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Study of Safer Kids: A Manualized Intervention to Prevent Child Abuse
Status: ACTIVE_NOT_RECRUITING
Conditions: Child Abuse|Child Maltreatment
Interventions: BEHAVIORAL: Safer Kids|OTHER: Intervention as usual (IAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Applesauce Study of Topiramate Sprinkle Capsules 25 mg and Topamax® Sprinkle Capsules 25 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Topiramate Sprinkle Capsules 25 mg|DRUG: Topamax® Sprinkle Capsules 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: D-chiro-inositol Increases Androgens and Reduces Estrogens in Human Serum
Status: COMPLETED
Conditions: Low Serum Testosterone Levels in Man
Interventions: DIETARY_SUPPLEMENT: D-chiro-inositol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zevalin (Ibritumomab Tiuxetan) for Early Stage Indolent Lymphomas
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Ibritumomab Tiuxetan (Zevalin)|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Immunogenicity of the Nonavalent Vaccine Against Human Papillomavirus in Men Infected by HIV Who Have Sex With Men. GESIDA 10017
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: HPV9v
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microvascular Assessment of Ranolazine in Non-Obstructive Atherosclerosis (MARINA)
Status: COMPLETED
Conditions: Microvascular Angina
Interventions: DRUG: Ranolazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study Of A New Alprazolam Dropped Formulation Versus Alprazolam Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: alprazolam tablet|DRUG: alprazolam oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Activity of Seviteronel in Patients With Androgen Receptor (AR)-Positive Glioblastoma
Status: TERMINATED
Conditions: Solid Tumor|Androgen Receptor Gene Overexpression
Interventions: DRUG: SEVI-D (Seviteronel in combination with dexamthasone)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on a High-Dose Quadrivalent Influenza Vaccine Compared With Standard-Dose Quadrivalent Influenza Vaccine in Children 6 Months Through 35 Months of Age
Status: SUSPENDED
Conditions: Influenza
Interventions: BIOLOGICAL: Quadrivalent influenza vaccine, high-dose|BIOLOGICAL: Quadrivalent influenza vaccine, standard dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multicenter Study to Assess the Efficacy and Safety of Methyl Aminolevulinate Hydrochloride (MAL) 16.8% Cream (CD06809-41) Versus Vehicle Cream for Actinic Keratosis of the Face
Status: COMPLETED
Conditions: Actinic Keratoses
Interventions: DRUG: MAL 16.8% cream|DRUG: MAL Vehicle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Naproxen Sodium 220 mg & Pseudoephedrine HCl 120 mg ER Tablets of Dr. Reddy's Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Naproxen Sodium & Pseudoephedrine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Guanfacine-er for Cannabis Use Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Cannabis Use
Interventions: DRUG: guanfacine-ER|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Angiogenesis in Women With Angina Pectoris Who Are Not Candidates for Revascularization
Status: UNKNOWN
Conditions: Angina Pectoris
Interventions: GENETIC: Ad5FGF-4|GENETIC: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of High-Dose Calcitriol Plus Temodar for Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: DIETARY_SUPPLEMENT: Calcitriol|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Needle Aspiration Techniques for Endoscopic Ultrasound-guided Fine Needle Aspiration (EUS-FNA) in Solid Pancreatic Lesions
Status: COMPLETED
Conditions: Pancreatic Solid Lesions|Pancreatic Mass
Interventions: DEVICE: Standard technique EUS-FNA|DEVICE: Capillary suction technique for EUS FNA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Pharmacology of 35/4 NEXThaler® in Children 5-11 Years Old
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: CHF 1535 35/4µg NEXThaler®|DRUG: free comb. beclomethasone DPI and formoterol DPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pterygium Excision on Intraocular Lens Power Calculation for Subsequent Cataract Operation
Status: UNKNOWN
Conditions: Pterygium|Cataract|Astigmatism
Interventions: PROCEDURE: pterygium excision
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiopulmonary Bypass on Mechanical Power and Postoperative Pulmonary Complications
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pulmonary Atelectasis|Pneumothorax|Pneumonia|Ards|Respiratory Failure
Interventions: OTHER: mechanical power calculation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multicentric, Randomized Study to Assess Safety and Efficacy of Centhaquine in COVID-19 Patients With ARDS
Status: NOT_YET_RECRUITING
Conditions: COVID-19 Acute Respiratory Distress Syndrome
Interventions: DRUG: Normal Saline|DRUG: Centhaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Immunogenicity of PENNVAX®-GP DNA Vaccine and IL-12 Plasmid, Delivered Via Intradermal or Intramuscular Electroporation in Healthy, HIV-Uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: PENNVAX®-GP HIV-1 DNA vaccine|BIOLOGICAL: Interleukin-12 (IL-12) DNA adjuvant|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Arsenic Trioxide in Treating Patients With Urothelial Cancer
Status: COMPLETED
Conditions: Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter|Recurrent Urethral Cancer|Transitional Cell Carcinoma of the Bladder|Ureter Cancer
Interventions: DRUG: arsenic trioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fenofibrate Combined With Ursodeoxycholic Acid in Subjects With Primary Biliary Cholangitis
Status: RECRUITING
Conditions: Primary Biliary Cholangitis
Interventions: DRUG: Placebo Combined With Ursodeoxycholic Acid|DRUG: Fenofibrate Combined With Ursodeoxycholic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Drug-Drug Interaction Study of N91115 +/- Rifampin in Healthy Adult Subjects
Status: COMPLETED
Conditions: Drug Interaction Potentiation
Interventions: DRUG: N91115|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Intermittent Fasting on Insulin Resistance, Cardiac Metabolism, and Cerebral Perfusion
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Intermittent fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: UC-MSC Transplantation for Left Ventricular Dysfunction After AMI
Status: NOT_YET_RECRUITING
Conditions: Left Ventricular Dysfunction|Acute Myocardial Infarction
Interventions: BIOLOGICAL: UC-MSC|BIOLOGICAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deploying Novel Imaging Modalities Towards a Three-dimensional (3D) CARDIOvascular PATHology
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Aortic Valve Disease|Aortic Valve Calcification|STEMI|Cardiovascular Pathology
Interventions: OTHER: Three-dimensional imaging of the collected cardiac specimens
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Prokinetic Agents in Improving Abdominal Discomfort at Colonoscopy
Status: UNKNOWN
Conditions: Abdominal Pain
Interventions: DRUG: Itopride|DRUG: Domperidone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Role of Micrometastasis and Isolated Tumor Cells (ITCs) in Endometrial and Cervical Cancer. A Multicenter Study.
Status: RECRUITING
Conditions: Endometrial Cancer|Cervical Cancer|Sentinel Lymph Node|Micrometastasis|Sentinel Lymph Node Biopsy|Endometrium Tumor|Endometrial Neoplasms|Cervical Neoplasm|Cervical Tumor|Lymph Node Metastases|Lymph Node Disease
Interventions: PROCEDURE: Sentinel lymph node (SLN) biosy +/- lymphadenectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Depression
Status: UNKNOWN
Conditions: Depression|Clinical Depression|Depression, Anxiety|Depression, Postpartum|Depression, Endogenous|Depression in Remission|Depression Chronic|Depression Moderate|Depression Severe
Interventions: OTHER: No Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Brain Stimulation (tDCS) in Food Cravings Control in Overweight/Obese Women
Status: UNKNOWN
Conditions: Obesity
Interventions: DEVICE: tDCS|DEVICE: Sham brain stimulation|BEHAVIORAL: Go-No GO task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Analgesia for Knee Arthroplasty (PAKA)
Status: COMPLETED
Conditions: Knee Arthritis
Interventions: DRUG: Femoral Nerve Block|DRUG: peri-articular infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: HIPEC-AS in Patients With Peritoneal Metastasis of the Stomach or Esophagogastric Junction
Status: NOT_YET_RECRUITING
Conditions: Stomach Neoplasms|Peritoneal Metastases
Interventions: PROCEDURE: HIPEC|DRUG: Paclitaxel-albumin|DRUG: Tegafur-gimeracil-oteracil potassium|PROCEDURE: Surgery+HIPEC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in People With Advanced Cancer to Test Whether the Amount of BI 907828 in the Blood is Influenced by Taking an OATP Inhibitor or a CYP3 Inhibitor
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumors
Interventions: DRUG: BI 907828|DRUG: Rifampicin|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growing Strong Study of Unconditional Cash Transfers Plus Peer Support for Families With Babies in Homeless Shelters
Status: RECRUITING
Conditions: Time to Shelter Exit|Family Well-being|Child Well-being
Interventions: BEHAVIORAL: Large unconditional cash transfers plus voluntary peer support.|BEHAVIORAL: Nominal cash transfers|BEHAVIORAL: Passive comparison group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized Controlled Study of Cyclophosphamide, Bevacizumab With or Without Envafolimab in Recurrent Epithelial Ovarian Cancer (EOC), Fallopian Tube Cancer, and Primary Peritoneal Cancer
Status: NOT_YET_RECRUITING
Conditions: Epithelial Ovarian Cancer
Interventions: DRUG: Envafolimab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Polyneuropathy, Impairments and Physical Activity - The PolyImPAct Study
Status: RECRUITING
Conditions: Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)|Vasculitic Neuropathy|POEMS Syndrome|Multifocal Motor Neuropathy|Charcot-Marie-Tooth|hATTR Amyloidosis|Diabetic Polyneuropathy|Idiopathic Neuropathy|Polyneuropathies
Interventions: OTHER: Validity and reliability of outcome measures in polyneuropathy|OTHER: Healthy controls
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HDAC Inhibitor Valproic Acid as an Effective Therapy for Chronic Lymphocytic Leukemia
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Valproic acid & fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Saquinavir Soft Gelatin Capsules Plus Zidovudine Plus Lamivudine in the Treatment of HIV-1 Infected Patients Who Have Never Taken Anti-HIV Drugs
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Saquinavir|DRUG: Lamivudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Acute Exercise Intervention in Breast Cancer Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Carcinoma
Interventions: BEHAVIORAL: Exercise Intervention|OTHER: Resting|OTHER: Biomarker Analysis|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Cardiovascular Effects of Air Pollution: the Role of Nitric Oxide
Status: COMPLETED
Conditions: Endothelial Dysfunction
Interventions: PROCEDURE: Forearm Vascular Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cabozantinib Combined With Ipilimumab/Nivolumab and TACE in Patients With Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|HCC
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|DRUG: Cabozantinib|PROCEDURE: Transarterial Chemoembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Effects of Telaprevir on the Pharmacokinetics of Cyclosporine and Tacrolimus in Healthy Adults
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: telaprevir|DRUG: telaprevir|DRUG: cyclosporine|DRUG: cyclosporine|DRUG: tacrolimus|DRUG: tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anesthetic Efficacy in Irreversible Pulpitis
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Intervention: inferior alveolar nerve block injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Online Intervention to Promote Resilience to Traumatic Stress During Pregnancy
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder|Pregnancy Related
Interventions: BEHAVIORAL: Sunnyside|BEHAVIORAL: SunnysideFlex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dosimetry Using a CZT-camera Following LUTATHERA® Therapy
Status: COMPLETED
Conditions: Dosimetry
Interventions: OTHER: Single Photon Emission Computed Tomography/ Computed Tomography (SPECT/CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Characterizing Diversity and Antifungal Resistance in Immunocompromised ICU Patients With Respiratory Tract Infections
Status: NOT_YET_RECRUITING
Conditions: Immunocompromised ICU Patients With Respiratory Tract Infections
Interventions: DIAGNOSTIC_TEST: Complete blood count|DIAGNOSTIC_TEST: C-reactive protein, urea, creatinine, Random blood glucose (RBG), aspartate aminotransferase (AST), alanine aminotransferase (ALT)|RADIATION: CT chest|DIAGNOSTIC_TEST: Microscopic examination|DIAGNOSTIC_TEST: culture and sensitivity
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vestibular Rehabilitation Exercises vs. General Fitness Training on Dizziness, Balance Confidence, and Mobility in Individuals With Bilateral Vestibular Hypofunction
Status: RECRUITING
Conditions: Vestibular Disorder
Interventions: BEHAVIORAL: Vestibular Rehabilitation Exercises|BEHAVIORAL: General Fitness Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Program After Total Hip and Knee Replacement: a Randomized Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Improve Quality of Life
Interventions: OTHER: Physical activity. Physical Activity program is performed in a group in a gym
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Tocilizumab in Cardiac Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Transplant
Interventions: BIOLOGICAL: tocilizumab|BIOLOGICAL: Placebo|DRUG: Standard of Care Triple IS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized, Multi-Center Evaluation of MediENT® Middle Turbinate Implant Versus MeroPack®, a Bioresorbable Nasal Dressing / Sinus Stent After Endoscopic Sinus Surgery
Status: COMPLETED
Conditions: Synechia
Interventions: DEVICE: MediENT|DEVICE: MeroPack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tenofovir Disoproxil Fumarate vs. Entecavir in Chronic Hepatitis B Patients With Partial Virologic Response to Entecavir
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: tenofovir|DRUG: entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fibroblast Growth Factor (FGFs) / Fibroblast Growth Factor Receptor (FGFRs) Genetic as a Second-line Therapy for Recurrent / Progressive Gastric Cancer With INCB054828 and Paclitaxel a Study to Evaluate the Safety and Efficacy of Combination Therapy.
Status: COMPLETED
Conditions: Fibroblast Growth Factors (FGFs)/Fibroblast Growth Factor Receptors (FGFRs) Genetic Aberration Gastric Cancer, INCB054828, Paclitaxel
Interventions: DRUG: INCB054828, Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simvastatin as Inhibitor of Cell Adhesion Mediated Drug Resistance in Patients With Refractory Multiple Myeloma.
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Dolutegravir Plus Lamivudine in HIV-1-infected Treatment-naïve Adults Without a Baseline Genotyping Test
Status: COMPLETED
Conditions: Hiv|HIV-1-infection
Interventions: DRUG: Lamivudine 300 MG|DRUG: Emtricitabine / Tenofovir Disoproxil Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy, Safety, and Relapse of ECT to ECT Plus Agomelatine for Depressed Patients
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: OTHER: electroconvulsive therapy|DRUG: agomelatine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preductal Oxygen Saturation Target in Term and Late Preterm Neonates With Hypoxemic Respiratory Failure or Pulmonary Hypertension
Status: ENROLLING_BY_INVITATION
Conditions: Persistent Pulmonary Hypertension of the Newborn|Hypoxemic Respiratory Failure
Interventions: OTHER: 95% - 99% SpO2 target
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relaxation Response Training for the Treatment of Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BEHAVIORAL: Relaxation response and cognitive behavioral therapy|BEHAVIORAL: Relaxation response|OTHER: RA education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Macugen (Pegaptanib Sodium) Alone, Versus Macugen in Combination With PDT (Photodynamic Therapy) With Visudyne (Verteporfin) in Patients With Age-Related Macular Degeneration (AMD)
Status: TERMINATED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: Photodynamic Therapy (PDT) with Visudyne (verteporfin)|DRUG: Macugen (pegaptanib sodium)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Palonosetron vs. Ondansetron for Postoperative Nausea and Vomiting in Bariatric Surgery
Status: COMPLETED
Conditions: Nausea, Postoperative|Vomiting, Postoperative|Patient Reported Outcomes|Pain, Postoperative|Antiemetics
Interventions: PROCEDURE: Laparoscopic sleeve gastrectomy|DRUG: Palonosetron 1mcg/kg|DRUG: Ondansetron 1 mg/kg, max dose 8 mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Serratus Posterior Intercostal Plane Block for Analgesia and Inflammatory Marker in Breast Surgery
Status: NOT_YET_RECRUITING
Conditions: Breastcancer|Perioperative Pain|Inflammation
Interventions: DRUG: Analgesia mangement group A,B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cancer-associated Muscle Mass - Molecular Factors and Exercise Mechanisms
Status: RECRUITING
Conditions: Cachexia|Neoplasms|Exercise|Metabolism|Body Composition|Insulin Resistance|Physical Functional Performance|Quality of Life|Sarcopenia|Caregivers|Adipose Tissue|Muscle, Skeletal|Patient Reported Outcome Measures|Gastrointestinal Microbiome|Proteomics|Lipidomics|Epigenomics|Mitochondria
Interventions: BEHAVIORAL: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Subject Reported Target-lesion Numeric Rating Scale Evaluation by Subjects With Plaque Psoriasis Treated With Clobex® (Clobetasol Propionate) Spray 0.05%
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Clobex Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Management of Complex Anal Fistulas by Installing a Closure Clip: Multicentre Randomized Controlled Trial
Status: UNKNOWN
Conditions: Complex Anal Fistula
Interventions: DEVICE: Closure clip (OTSC® Proctology)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Psychological and Emotional Impact in Patients Undergoing Treatment For Metastatic Cancer Either in a Clinical Trial or as Standard Off-Trial Therapy
Status: TERMINATED
Conditions: Anal Cancer|Anxiety Disorder|Breast Cancer|Depression|Esophageal Cancer|Gallbladder Cancer|Gastric Cancer|Kidney Cancer|Liver Cancer|Lung Cancer|Pancreatic Cancer|Small Intestine Cancer
Interventions: OTHER: questionnaire administration|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Chemotherapy as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors of the Duodenum or Pancreas That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Gastrointestinal Carcinoid Tumor|Islet Cell Tumor|Neoplastic Syndrome
Interventions: DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy With Lutetium Texaphyrin in Treating Patients With Locally Recurrent Prostate Cancer
Status: TERMINATED
Conditions: Adenocarcinoma of the Prostate|Recurrent Prostate Cancer|Stage I Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer
Interventions: DRUG: motexafin lutetium|DRUG: photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of TMZ Plus 6-MP in the Patients With Recurrent Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma|Cancer|Temozolomide
Interventions: DRUG: 6-mercaptopurine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Thermal Condition of Health Workers Who Use Personal Protective Equipment From Biological Hazards During Their Work With COVID-19 Patients
Status: COMPLETED
Conditions: Thermal Condition of Health Workers Who Use Personal Protective Equipment From Biological Hazards During Their Work With COVID-19 Patients
Interventions: OTHER: Personal protective equipment from biological hazard
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Endoscopic Nasopharyngectomy for Newly Diagnosed Stage I Nasopharyngeal Carcinoma Patients
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma|Endoscopic Surgery|Primary Napharyngeal Carcinama|Stage I Nasopharyngeal Cancer
Interventions: PROCEDURE: Endoscopic surgery|RADIATION: Intensity-modulated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT