pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effectiveness of Virtual Nature-based Intervention During First Stage of Labour
Status: RECRUITING
Conditions: Anxiety|Fear of Childbirth|Stress|Pain|Childbirth Experience
Interventions: OTHER: Virtual nature-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Follow-up Study of L059 (Levetiracetam) in Epileptic Patients With Partial Onset Seizures by Open Label Method
Status: COMPLETED
Conditions: Epilepsy, Partial
Interventions: DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Strip PeriScreen for the Fast Diagnosis of the Spontaneous Infection of the Liquid of Ascites During the Cirrhosis
Status: COMPLETED
Conditions: Cirrhosis|Liquid of Ascites|Infection
Interventions: OTHER: strip Peri Screen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Paravertebral Versus Caudal Block in Pediatric PCNL
Status: UNKNOWN
Conditions: Kidney Stones|Percutaneous Nephrolithotomy
Interventions: PROCEDURE: Paravertebral|PROCEDURE: Caudal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gradient-Echo Spectroscopic Imaging Study of Saturated Fat and Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DIAGNOSTIC_TEST: Diagnostic Breast Cancer Scan|DIAGNOSTIC_TEST: Research Scan for Gradient-echo Spectroscopic Imaging (GSI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Manual Therapy for the Treatment of Shoulder Pain for Overuse Syndrome Wheelchair Dependent Persons
Status: COMPLETED
Conditions: Spinal Cord Injuries|Pain|Musculoskeletal Manipulations
Interventions: OTHER: Manual Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Allogeneic Human UC-MSC and Liberation Therapy (When Associated With CCSVI) in Patients With RRMS
Status: UNKNOWN
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: BIOLOGICAL: Allogeneic Human Umbilical Cord Tissue-Derived Mesenchymal Stem Cells|OTHER: Liberation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Busulfan, Melphalan and Etoposide as Conditioning for Autologous Transplantation for Non-Hodgkin's Lymphoma (NHL)
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Busulfan|DRUG: Melphalan|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine, Nab-paclitaxel Plus the TheraBionic P1 (an Amplitude-Modulated Radiofrequency Electromagnetic Fields) Device to Treat Metastatic Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: Nab paclitaxel|DRUG: Gemcitabine|DEVICE: TheraBionic P1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Refining the Target for Deep Brain Stimulation (DBS) in Severe, Treatment Refractory Obsessive Compulsive Disorder (OCD)
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: VC/VS stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Levetiracetam for the Treatment of Alcohol Dependence and Anxiety
Status: COMPLETED
Conditions: Alcoholism|Generalized Anxiety Disorder|Panic Disorder|Social Phobia|Anxiety Disorders
Interventions: DRUG: levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab and Olaparib in Metastatic or Recurrent Endometrial Cancer
Status: UNKNOWN
Conditions: Endometrial Neoplasms|Uterine Neoplasms|Endometrium Cancer
Interventions: DRUG: PARP inhibitor and Anti-PD-L1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Acne Vulgaris Using NAFL in Combination With Isotretinoin and Pricking Blood Therapy
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: RADIATION: 1,565nm NAFL|DRUG: Oral isotretinoin|OTHER: Pricking blood therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Selective Caries vs Stepwise Caries Removal Technique in Deep Carious Lesions
Status: UNKNOWN
Conditions: Caries
Interventions: PROCEDURE: Selective caries removal|PROCEDURE: Stepwise caries removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of the Safety, Tolerance, and Pharmacokinetics of 9-(2-Phosphonylmethoxyethyl)Adenine ( PMEA; Adefovir ) in Patients With Advanced HIV Disease.
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Adefovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Memantine and Naltrexone Treatment for Opioid Dependence
Status: COMPLETED
Conditions: Opioid Dependence
Interventions: DRUG: Memantine|DRUG: Naltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PK, PD, Safety and Tolerability of Lipegfilgrastim in Healthy Japanese and Caucasian Participants
Status: COMPLETED
Conditions: Pharmacokinetics|Pharmacodynamics
Interventions: DRUG: lipegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Tart Cherry Juice on Risk of Gout Attacks
Status: TERMINATED
Conditions: Gout Flare|Gout Attack
Interventions: DIETARY_SUPPLEMENT: Tart cherry juice|OTHER: Fruit-flavoured placebo drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Lumbar Motor Control Training in Treatment Of Patients With Cervicogenic Headache
Status: NOT_YET_RECRUITING
Conditions: Cervicogenic Headache
Interventions: OTHER: lumbar motor control exercises|OTHER: Cervical stabilization exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Post-operative Assessment of Chronic Signs & Symptoms Related to Infected Primary Molars After Using Rotary Versus Manual Systems in Cleaning the Root Canals
Status: UNKNOWN
Conditions: Chronic Infection
Interventions: DEVICE: Rotary files
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hot Bag/Warm Application on Feet After Cesarean Delivery on Postpartum Comfort, Pain and Flatus
Status: COMPLETED
Conditions: Cesarean Section Complications|Pain|Postpartum Anxiety
Interventions: OTHER: Warm Application to Feet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Induced Angiogenesis by Genic Therapy in Advanced Ischemic Cardiomyopathy
Status: UNKNOWN
Conditions: Ischemic Cardiopathy
Interventions: PROCEDURE: Mini-thoracotomy for intramyocardial injection of VEGF165
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identifying Correlates of Brain Microglial Activation in Neuropsychiatric Syndromes: A Dimensional Approach
Status: RECRUITING
Conditions: Neuropsychiatric Syndromes
Interventions: DRUG: PET with radiotracer [11C]PBR-28 ( or [11C]ER176)|OTHER: Affective challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Study of of Metformin HCl From Gleptomet 50/1000 mg F.C.Tablets (EVA Pharma, Egypt) and Janumet 50/1000 mg F.C.Tablets (Merck Sharp & Dohme, The Netherlands)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Gleptomet 50/1000(Metformin HCl & Sitagliptin)|DRUG: Janumet 50/1000(Metformin HCl & Sitagliptin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Feasibility of a New Diagnostic Device to Assess Small Intestinal Dysbiosis in Routine Clinical Setting.
Status: RECRUITING
Conditions: Small Intestinal Bacterial Overgrowth
Interventions: DEVICE: Atmo Gas Capsule|DIAGNOSTIC_TEST: Glucose Breath Test|DIAGNOSTIC_TEST: Fructoolifosaccharides (FOS) Breath Test|PROCEDURE: Jejunal Aspiration and culture|DRUG: Rifaximin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Postoperative Adjuvant Therapy of Donafenib for Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Adjuvant Therapy
Interventions: DRUG: Donafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Morphine and Fentanyl for Knee Arthroplasty
Status: UNKNOWN
Conditions: Knee Arthroplasty
Interventions: DRUG: Intrathecal morphine|DRUG: Intrathecal fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Symptom Based Treatment Affects Brain Plasticity - the Role of Verbal Auditory Hallucinations
Status: COMPLETED
Conditions: Hallucinations, Verbal Auditory
Interventions: PROCEDURE: fMRI|BEHAVIORAL: Neurofeedback|OTHER: PANAS|OTHER: AVHRS|OTHER: SF36
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of Treatment of Bacterial Vaginosis
Status: TERMINATED
Conditions: Bacterial Vaginoses
Interventions: DRUG: Metronidazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Propranolol Hydrochloride 160 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Propranolol Hydrochloride Extended Release Capsules 160 mg|DRUG: INDERAL® LA 160 mg Capsules, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Trial of Family Focused Grief Therapy in Palliative Care and Bereavement
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer
Interventions: BEHAVIORAL: Family Focused Group Therapy|BEHAVIORAL: Family Focused Group Therapy|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Induction Therapy With a Single High Dose Bolus of Intravenous Methotrexate With Leucovorin Rescue, Prior to Initiation of AVONEX® Treatment, in Patients Presenting With a First Acute Demyelinating Event.
Status: WITHDRAWN
Conditions: Demyelinating Disorders|Multiple Sclerosis|Optic Neuritis|Myelitis|Neuritis
Interventions: DRUG: interferon beta 1a|DRUG: methotrexate|DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive Disorder
Status: RECRUITING
Conditions: Major Depressive Disorder|Inflammation|Cognitive Dysfunction|Endotoxemia|Genetic Predisposition to Disease|Blood Brain Barrier Defect
Interventions: DIAGNOSTIC_TEST: The Cambridge Neuropsychological Test Automated Battery.|DIAGNOSTIC_TEST: Venous blood samples|DIAGNOSTIC_TEST: brain MRI|DIAGNOSTIC_TEST: the Montgomery-Åsberg Depression Rating Scale|OTHER: questionnaire prepared by the researchers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lung Cancer Cryo-Activation as a Novel Approach to Augment Immunotherapy Efficacy (CRYOVATE)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer Metastatic|Cryotherapy Effect
Interventions: PROCEDURE: Cryo-activation|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Redirected RNA Meso CAR T Cells for Pancreatic Cancer
Status: COMPLETED
Conditions: Subjects With Metastatic Pancreatic Ductal Adenocarcinoma (PDA)
Interventions: BIOLOGICAL: Autologous T cells transfected with chimeric anti-mesothelin immunoreceptor SS1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of SGLT2 Inhibition on the Mechanisms of Cardiac Damage in the Diabetic Patient With HFpEF
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: Dapagliflozin 10 MG [Farxiga]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of KT VS ST Along With Routine Physical Therapy Among Patients of Chronic Low Back Pain RCT
Status: RECRUITING
Conditions: Low Back Pain
Interventions: DIAGNOSTIC_TEST: Kinesio taping|DIAGNOSTIC_TEST: Sham taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effectiveness of Neurodynamic Sliding Mobilisation in the "Slump" Position in Relation to the Perceptible Pain Threshold in Asymptomatic People
Status: NOT_YET_RECRUITING
Conditions: Voluntary
Interventions: OTHER: "slump"position|OTHER: no" slump" position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy of CaroRite™ on Psychological Well-being, Oxidative Stress and Quality of Life in Healthy Individuals
Status: COMPLETED
Conditions: Psychological Well-Being|Oxidative Stress|Quality of Life
Interventions: DIETARY_SUPPLEMENT: CaroRite™|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A 24-week Study to Compare Umeclidinium/Vilanterol (UMEC/VI), UMEC and Salmeterol in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: UMEC/VI 62.5/25 mcg via ELLIPTA|DRUG: UMEC 62.5 mcg via ELLIPTA|DRUG: Salmeterol 50 mcg via DISKUS|DRUG: Placebo via ELLIPTA|DRUG: Placebo via DISKUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Impact of the iBox as an Early Intervention tooL
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Diseases|Kidney Disease, Chronic|Kidney Transplant Rejection|Kidney Transplant; Complications|Kidney Failure|Kidney Failure, Chronic|Kidney Dysfunction
Interventions: DEVICE: Predigraft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Usability and Effectiveness of ReHub in Patients After Total Hip Arthroplasty
Status: TERMINATED
Conditions: Hip Osteoarthritis
Interventions: OTHER: Conventional Home-based Rehabilitation Plan|DEVICE: ReHub Home-based Rehabilitation Plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New Ulm at HOME (Healthy Offerings Via the Mealtime Environment), NU-HOME
Status: COMPLETED
Conditions: Obesity, Childhood|Physical Activity|Food Intake|Rural Health
Interventions: BEHAVIORAL: NU-HOME Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Development and Initial Evaluation of a Web-based, Compassion-focussed Course for New Mothers
Status: COMPLETED
Conditions: New Mothers' Well-being
Interventions: OTHER: Kindness for Mums
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Calorie Restriction in Multiple Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting|Caloric Restriction
Interventions: OTHER: Caloric restriction|OTHER: Caloric restriction without cow's milk and gluten
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fatigue in Chronic Pain - Cognition, Emotional Aspects, Biomarkers, and Neuronal Correlates
Status: COMPLETED
Conditions: Pain|Fatigue|Cognitive Impairment
Interventions: DIAGNOSTIC_TEST: Neuropsychological (NPA)|OTHER: Imaging|DIAGNOSTIC_TEST: Inflammatory biomarkers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II)
Status: NOT_YET_RECRUITING
Conditions: Delirium
Interventions: DRUG: Intravenous Dexmedetomidine|DRUG: Sublingual Dexmedetomidine|DRUG: Intravenous Placebo|DRUG: Sublingual Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Guided Lateral Sphincterotomy: Long Term Results
Status: UNKNOWN
Conditions: Focus: Anal Incontinence After Lateral Sphincterotomy for Chronic Anal Fissure
Interventions: PROCEDURE: lateral sphincterotomy|PROCEDURE: ultrasound guided lateral sphincterotomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Changes in Liver Steatosis After Switching to Raltegravir in HIV/HCV Coinfection
Status: COMPLETED
Conditions: HCV Coinfection|HIV Infection
Interventions: DRUG: Raltegravir|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Amniotic Membrane (hAM) for Stage II Maxillomandibular Osteonecrosis Management
Status: RECRUITING
Conditions: Osteonecrosis Due to Drugs, Jaw
Interventions: BIOLOGICAL: Human Amniotic Membrane|OTHER: Conventional/Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Alfuzosin for the Treatment of Voiding Dysfunction in Female
Status: COMPLETED
Conditions: Voiding Dysfunction
Interventions: DRUG: alfuzosin hydrochloride XL 10mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hip Abductor Tendon Repair Versus Sham Surgery
Status: RECRUITING
Conditions: Rupture of Hip Abductor Tendon (Disorder)
Interventions: PROCEDURE: Surgical reconstruction of hip abductor tendon tear|PROCEDURE: Sham surgery of hip abductor tendon tear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Clinical Study Using an Artery-first Intermediate Approach in Robot-assisted Pancreaticoduodenectomy
Status: RECRUITING
Conditions: Pancreatic Cancer|Common Bile Duct Diseases|Periampullary Carcinoma
Interventions: PROCEDURE: Intermediate approach|PROCEDURE: Standard approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory Rhabdomyosarcoma
Status: COMPLETED
Conditions: Adult Rhabdomyosarcoma|Childhood Alveolar Rhabdomyosarcoma|Childhood Pleomorphic Rhabdomyosarcoma|Childhood Rhabdomyosarcoma With Mixed Embryonal and Alveolar Features|Previously Treated Childhood Rhabdomyosarcoma|Recurrent Adult Soft Tissue Sarcoma|Recurrent Childhood Rhabdomyosarcoma
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Cyclophosphamide|OTHER: Laboratory Biomarker Analysis|DRUG: Temsirolimus|DRUG: Vinorelbine Tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Time-restricted Eating on Cognitive Function and Other Biopsychosocial Factors in Menopausal Women Undertaking a 12-week Exercise Programme
Status: COMPLETED
Conditions: Menopause|Cognitive Deficits, Mild
Interventions: BEHAVIORAL: Exercise and Time-Restricted Eating|BEHAVIORAL: Exercise only
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase IV Trial of Paritaprevir/Ritonavir, Ombitasvir, Dasabuvir for Chronic Hepatitis C Genotype 1 Virus Infection
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: "3D" regimen|DRUG: "3D" regimen with ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Crossover Study of Magnesium Supplementation
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Inflammation
Interventions: DIETARY_SUPPLEMENT: Magnesium Citrate: a total of 500 mg elemental magnesium|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Utility of Endobronchial Ultrasound Guided Needle Biopsy in Early Stage Non- Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Lung Cancer
Interventions: PROCEDURE: EBUS-TBNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obstruction of Malignancy: Percutaneous Renal vs Endoscopic Stent
Status: RECRUITING
Conditions: Cancer|Urinary Obstruction|Malignancy|Urinary Dysfunction|Ureter Obstruction|Ureter Injury
Interventions: PROCEDURE: Ureteral Stent|PROCEDURE: Percutaneous Nephrostomy Tube Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Fruit and Fruit Juice on Plasma Total Antioxidant Capacity
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Order 1|DIETARY_SUPPLEMENT: Order 2|DIETARY_SUPPLEMENT: Order 3|DIETARY_SUPPLEMENT: Order 4|DIETARY_SUPPLEMENT: Order 5|DIETARY_SUPPLEMENT: Order 6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of the Use of Occlusal Splint on the Postural Balance of Individuals With Temporomandibular Disorder
Status: COMPLETED
Conditions: Temporomandibular Disorders
Interventions: PROCEDURE: occlusal plate|PROCEDURE: therapeutic exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-dose Venetoclax and Azacitidine as Front-line Therapy in Newly Diagnosed AML
Status: COMPLETED
Conditions: AML
Interventions: DRUG: Venetoclax 100 MG|DRUG: Itraconazole capsule|DRUG: Azacitidine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Determine the Safety and Efficacy of Hope Biosciences Autologous Mesenchymal Stem Cell Therapy for the Treatment of Traumatic Brain Injury and Hypoxic-Ischemic Encephalopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Traumatic Brain Injury
Interventions: BIOLOGICAL: HB-adMSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of the GlucoWatch G2 Biographer for the Management of Type 1 Diabetes in Children
Status: COMPLETED
Conditions: Diabetes Mellitus, Insulin-Dependent
Interventions: DEVICE: GlucoWatch® G2™ Biographer (GW2B)|DEVICE: Continuous Glucose Monitoring System™ (CGMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Extension of Letermovir (LET) From Day 100 to Day 200 Post-transplant for the Prevention of Cytomegalovirus (CMV) Infection in Hematopoietic Stem Cell Transplant (HSCT) Participants (MK-8228-040)
Status: COMPLETED
Conditions: Cytomegalovirus Infection
Interventions: DRUG: Letermovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of the Efficacy and Safety of AC0010 in the Treatment of EGFR T790M Patients With Advanded NSCLC
Status: UNKNOWN
Conditions: Metastatic Non-small Cell Lung Cancer
Interventions: DRUG: AC0010
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Comparing Two Non-Surgical Treatments for Severe Blepharoptosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Blepharoptosis|Ptosis, Eyelid|Myasthenia Gravis|Stroke|Traumatic Brain Injury|Chronic Progressive External Ophthalmoplegia
Interventions: DEVICE: Magnetic Levator Prosthesis (MLP)|DEVICE: Kinesiotape Frontalis Sling (KTFS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TDM of Gentamicin and Vancomycin, in Neonates, Using Dried Blood Spot Sampling.
Status: UNKNOWN
Conditions: Blood Sample for Routine Care|Term or Premature Newborns (28 to 44 Amenorrhea Weeks)|Gentamicin and/or Vancomycin
Interventions: DIAGNOSTIC_TEST: therapeutic drug monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Insulin Glargine U300 vs Insulin Degludec U100 in Impact on the Glycaemic and Cardiovascular Factors
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Degludec|DRUG: Glargine U300
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Underlying Renal Disease and Immunosuppressive Regimen on Ovarian Reserve in Renal Patients
Status: COMPLETED
Conditions: Anti-Mullerian Hormone Deficiency|Immunosuppression|Ovarian Reserve|X-rays; Effects
Interventions: DIAGNOSTIC_TEST: AMH level measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Albumin Paclitaxel Combined With Cisplatin Chemoradiotherapy for Non-resectable Stage III NSCLC
Status: UNKNOWN
Conditions: Efficacy and Safety
Interventions: DRUG: Albumin paclitaxel combined with cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention Interventions for Opioid Misuse
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid Use
Interventions: BEHAVIORAL: Brief intervention (BI)|BEHAVIORAL: Portal|BEHAVIORAL: Enhanced Usual Care (EUC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Study of TAK-007 in Adults With Relapsed or Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed or Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)
Interventions: BIOLOGICAL: TAK-007|DRUG: Chemotherapy Agents
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Exposure Reduction Using Region-of-Interest Fluoroscopy (X-ray Fovea Imaging) in Cardiac Interventions
Status: UNKNOWN
Conditions: Cardiovascular Diseases
Interventions: DEVICE: Region-of-Interest Imaging (X-ray Fovea Imaging)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: DaxibotulinumtoxinA for Injection for the Treatment of Plantar Fasciitis
Status: COMPLETED
Conditions: Plantar Fasciitis
Interventions: BIOLOGICAL: DAXI 80 U|BIOLOGICAL: DAXI 120 U|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Complementary and Alternative Medicine on Mental Health in Breast Cancer Patients
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: OTHER: Complementary and alternative medicines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility of Activity Monitoring in Patients With Cancer: Physical Activity Monitoring in Cancer Patients (PAMCaP)
Status: COMPLETED
Conditions: Gastrointestinal Cancer|Breast Cancer|Gynecologic Cancer|Genitourinary Cancer|Leukemia|Lung Cancer|Skin Cancer|Endocrine Cancer|Male Genital Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Workplace Environment Study of Lisdexamfetamine Dimesylate (LDX) in Adults With Attention-Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: LDX|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Weekly Chest Radiotherapy and Oral Navelbine for the Palliation of Advanced Non Small Cell Lung Cancer: A Phase I Study
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: chemotherapy|PROCEDURE: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety of Vitamin D Receptor Activators in Patients Ages 0 to 16 With Chronic Kidney Disease Stage 5 Receiving Peritoneal Dialysis Within Current Clinical Practice
Status: TERMINATED
Conditions: Secondary Hyperparathyroidism|End-Stage Renal Disease
Interventions: DRUG: Paricalcitol|DRUG: Calcitriol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Efficacy of Botulinum Toxin Serotype A Injections for Cervicobrachial Myofascial Syndrome
Status: COMPLETED
Conditions: Cervicobrachial Neuralgia|Myofascial Pain Syndromes
Interventions: DRUG: Botulinum toxin serotype A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Scaling and Root Planing (SRP) With and Without Minocycline HCl Microspheres, 1 mg
Status: COMPLETED
Conditions: SRP|Minocycline HCl Microspheres|Biomarkers
Interventions: DRUG: minocycline HCl microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Excision Margins After Neoadjuvant Chemoimmunotherapy for HPV Negative Resectable Locally Advanced HNSCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma of Head and Neck|Neoadjuvant Therapy|Resection Margin
Interventions: PROCEDURE: Reducing Excision Margins
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and AMD3100
Status: COMPLETED
Conditions: Fanconi Anemia
Interventions: DRUG: AMD3100|DEVICE: AmCell CliniMACs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Serum Levels of C Type Natriuretic Peptide in Different Reproductive Periods
Status: COMPLETED
Conditions: Serum CNP Levels|Healthy Reproductive Age Women|Healthy Perimenopausal Women|Healthy Postmenopausal Women
Interventions: DIAGNOSTIC_TEST: C Type Natriüretic Peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Ultrasound Guided : Retrolaminar Block Versus Thoracic Epidural Analgesia Following Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Analgesia
Interventions: PROCEDURE: Bilateral retrolaminar block|PROCEDURE: Thoracic epidural analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3b Study to Evaluate Subject Satisfaction With Follitropin Alfa Injection in Oligoanovulatory Infertile Women Undergoing Ovulation Induction
Status: COMPLETED
Conditions: Infertility
Interventions: DEVICE: Follitropin alfa injected by Pen device|DEVICE: Recombinant Human Choriogonadotropin (r-hCG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retrospective Study of the Uni-Graft® K DV Patch in the Clinical Routine
Status: ENROLLING_BY_INVITATION
Conditions: Femoral Artery Stenosis|Iliac Artery Stenosis|Carotid Artery Stenosis
Interventions: DEVICE: Vascular reconstruction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Immunogenicity of Two Doses of a Tetravalent Influenza Vaccine in Adults Aged 18 Years and Above
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: MF59-eTIV-H5N1+ placebo /pandemic influenza vaccine|BIOLOGICAL: Pandemic influenza vaccine + placebo /MF59-eTIV-H5N1|BIOLOGICAL: Pandemic influenza vaccine + seasonal influenza vaccine /pandemic influenza vaccine|BIOLOGICAL: Pandemic influenza vaccine + placebo / MF59-eTIV-H5N1|BIOLOGICAL: Pandemic influenza vaccine + seasonal influenza vaccine / pandemic influenza vaccine|BIOLOGICAL: MF59-eTIV-H5N1 + Placebo/pandemic influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study to Evaluate the Efficacy and Safety of CKD-348(CKD-828, D326, D337) Tablet
Status: UNKNOWN
Conditions: Hypertension|Dyslipidemias
Interventions: DRUG: CKD-828|DRUG: CKD-828(placebo)|DRUG: D326|DRUG: D326(placebo)|DRUG: D337|DRUG: D337(placebo)|DRUG: D013|DRUG: D013(placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Everolimus in Combination With Cyclosporine A and Prednisolone for the Treatment of Graft Versus Host Disease
Status: TERMINATED
Conditions: Graft Versus Host Disease
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Vaccination in Rheumatic Disease Patients
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus|Sjogren's Syndrome|Inflammatory Myositis|Psoriatic Arthritis|Gout|Ankylosing Spondylitis|Arthritis of Multiple Sites Associated With Inflammatory Bowel Disease (Diagnosis)|Osteoarthritis
Interventions: BIOLOGICAL: mRNA COVD19 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy Study of Tamsulosin and Tolterodine Treatment for Chronic Prostatitis
Status: UNKNOWN
Conditions: Prostatitis
Interventions: DRUG: tolterodine|DRUG: tamsulosin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Drug Interaction Between YH4808 and Diclofenac
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: YH4808|DRUG: Diclofenac|DRUG: YH4808+Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Single Ascending Dose Study of Daclatasvir (BMS-790052) in Hepatitis C Virus Infected Subjects
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Daclatasvir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of UX701 Gene Transfer for the Treatment of Wilson Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Wilson Disease
Interventions: GENETIC: UX701|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double Sequential External Defibrillation in Patients With Atrial Fibrillation Refractory to DC Cardioversion
Status: UNKNOWN
Conditions: Atrial Fibrillation|Defibrillators|Persistent Atrial Fibrillation
Interventions: DEVICE: Double sequential external defibrillation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of BIA 9-1067 on Cardiac Repolarization in Healthy Adult Men and Women
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: BIA 9-1067|DRUG: Placebo|DRUG: moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin in Combination With Irinotecan in Ewing Sarcoma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Ewing Sarcoma
Interventions: DRUG: Trabectedin 1 MG [Yondelis]|DRUG: Irinotecan|DIAGNOSTIC_TEST: tumor biopsy|OTHER: 3'-Deoxy-3'-18F Fluorothymidine (18F-FLT) Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3D Modeling of the Cervico-facial Region and Cranial Nerve Tractography: IMAG 2 ORL Project
Status: RECRUITING
Conditions: Head and Neck Neoplasms|Congenital Abnormalities
Interventions: OTHER: Tractography MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intensive Insulin Therapy as Therapeutic Strategy for Non-diabetic Hyperglycemia After Surgery in ICU
Status: COMPLETED
Conditions: Hyperglycemia|Postoperative Complications|Insulin Resistance
Interventions: DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention on Non-prescription Antibiotic Use Among the Public
Status: COMPLETED
Conditions: Non-Prescription Drug Misuse|Antibiotic Use
Interventions: BEHAVIORAL: WeChat-based health education on antibiotic use|BEHAVIORAL: Regular public health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Integrated Prevention and Treatment on Child Malnutrition and Health in Mali: a Cluster Randomized Intervention Study
Status: COMPLETED
Conditions: Child Acute Malnutrition
Interventions: DIETARY_SUPPLEMENT: Small-Quantity Lipid-based nutrient supplement|BEHAVIORAL: Child's health and nutrition topics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Low Level Laser Therapy on Functional Capacity and DNA Damage of Patients With Chronic Kidney Failure
Status: COMPLETED
Conditions: Low-Level Light Therapy|Renal Insufficiency, Chronic|Renal Dialysis|Clinical Trial
Interventions: OTHER: Low Level Laser Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-blind Pilot Study to Investigate Safety and Tolerability of the Chymase Inhibitor BAY1142524 in Clinically Stable Patients With Left-ventricular Dysfunction
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: BAY1142524|DRUG: BAY1142524|DRUG: BAY1142524|DRUG: BAY1142524|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study on the Tolerance and Pharmacokinetics of GST-HG141 Tablets
Status: UNKNOWN
Conditions: Hepatitis B
Interventions: DRUG: GST-HG141 tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Repurposed Drug Added to the Combination of Len Plus Pem in Advanced Endometrial Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced Endometrial Cancer
Interventions: DRUG: EG-007|DRUG: Pembrolizumab 100 mg/ 4 ml (25 mg/ml) Injection|DRUG: Lenvatinib Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Occurrence of Post-op Pain Following Gentlewave
Status: COMPLETED
Conditions: Root Canal Infection|Endodontic Disease|Endodontic Inflammation|Post-Operative Pain
Interventions: DEVICE: Gentlewave|PROCEDURE: Standard Endodontic Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Electroencephalographic (EEG) Seizure Treatment in Neonatal Encephalopathy
Status: COMPLETED
Conditions: Seizures|Encephalopathy
Interventions: OTHER: EEG monitoring and treatment of EEG seizures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Vein Isolation (PVI) Combined With Renal Denervation (RDN) in Atrial Fibrillation (AF) and Hypertension (HTN)
Status: RECRUITING
Conditions: AF - Atrial Fibrillation|HTN-Hypertension
Interventions: OTHER: Renal Denervation operation|OTHER: Pulmonary vein isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conservative Iron Chelation as a Disease-modifying Strategy in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Deferiprone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess the Safety and Efficacy of Topical Salbutamol in Healthy Volunteers.
Status: COMPLETED
Conditions: Scarring
Interventions: PROCEDURE: Incision|DRUG: Active gel|DRUG: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of DApagliflozin on Cardiac Function Following Anterior Myocardial Infarction in Non-Diabetic Patients
Status: COMPLETED
Conditions: Anterior MI
Interventions: DRUG: Dapagliflozin 10mg|DRUG: Glucose Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Intravenous (IV) ABBV-637 Alone or in Combination With IV Docetaxel/Osimertinib to Assess Adverse Events and Change in Disease Activity in Adult Participants With Relapsed/Refractory (R/R) Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors Cancer|Non Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: ABBV-637|DRUG: Docetaxel|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Central Malignant Airway Obstructions: Medical Treatment Alone Versus Endoscopic and Medical Treatmen
Status: COMPLETED
Conditions: Endobronchial Mass|Lung Cancer
Interventions: OTHER: Comparison between patients with Patients with central malignant airway obstructions undergoing medical treatment alone versus medical and endoscopic treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Comparing the DOVER Silver Foley Catheter to a Standard of Care Catheter and a Marketed Silver Coated Foley Catheter
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DEVICE: Standard Latex Foley Catheter|DEVICE: Silver Coated Latex Foley Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION