pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Personalized Parkinson Project de Novo Cohort
Status: UNKNOWN
Conditions: Parkinson Disease|Parkinsonian Disorders|Basal Ganglia Diseases|Brain Diseases|Central Nervous System Diseases|Nervous System Diseases|Movement Disorders|Neurodegenerative Diseases
Interventions: DEVICE: Verily Study Watch
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Home Exercise Program Using Bootle Boot Camp
Status: NOT_YET_RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: Bootle Boot Camp Home Exercise App - with Virtual Coach Botley|OTHER: Bootle Boot Camp Home Exercise App - without Virtual Coach Botley
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Optimising Patient Experience in Head and Neck Radiotherapy
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: DEVICE: Conventional 5 point closed face immobilisation mask.|DEVICE: 5 point open face immobilization mask|DEVICE: 3 point open face immobilization mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Keratoconus in Inflammatory Bowel Diseases
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Keratoconus
Interventions: DEVICE: Opthalmologic measure with DM OPD scan III (Nidek)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Alfuzosin for Medical Expulsion Therapy of Ureteral Stones
Status: UNKNOWN
Conditions: Kidney Stones
Interventions: DRUG: Alfuzosin|DRUG: nifedipine|DRUG: doxazosin|DRUG: prazosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epcoritamab-CAR T Cells for Large B-cell Lymphomas
Status: NOT_YET_RECRUITING
Conditions: Lymphoma, Non-Hodgkin|Relapsed Diffuse Large B Cell Lymphoma|Refractory Diffuse Large B-cell Lymphoma|High-grade B-cell Lymphoma|Transformed Indolent Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Epcoritamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Cellular Pharmacology of F-TAF in Dried Blood Spots
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: emtricitabine 200 mg/tenofovir alafenamide 25mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Exenatide in Patients With Diabetic Neuropathy
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Diabetic Peripheral Neuropathy
Interventions: DRUG: Exenatide|DRUG: Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of High Dose N-acetylcysteine on Airtrapping and Airway Resistance in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: N-acetycysteine (600mg twice daily)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypothesizing the Genesis of Infectious Diseases and Epidemics Through an Integrated Systems Biology Approach
Status: RECRUITING
Conditions: SARS-CoV-2 Infection|Influenza Viral Infections
Interventions: BIOLOGICAL: blood samples, urine samples and nasopharyngeal swabs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Anchor Versus Parachute Suturing Technique in Arteriovenous Fistula Creation for Hemodialysis
Status: RECRUITING
Conditions: Arterio-venous Fistula
Interventions: OTHER: suturing technique in arteriovenous fistula creation for hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Loteprednol Ophthalmic Gel for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery
Status: COMPLETED
Conditions: Inflammation|Pain|Cataract
Interventions: DRUG: Loteprednol Etabonate Gel (BID)|DRUG: Loteprednol Etabonate Gel (TID)|DRUG: Vehicle (BID)|DRUG: Vehicle (TID)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CiNPWT Lower Extremity Amputations (Closed Incision Neagtive Pressure Wound Therapy)
Status: NOT_YET_RECRUITING
Conditions: Wound Heal|Wound Dehiscence
Interventions: PROCEDURE: Standard of Care group|DEVICE: CINPWT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of AEM-28 to Treat Refractory Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia|Hyperlipoproteinemia Type II
Interventions: DRUG: AEM-28|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: THRomboprophylaxis in Individuals Undergoing Superficial endoVEnous Treatment (THRIVE)
Status: RECRUITING
Conditions: Venous Thromboembolism|Varicose Veins
Interventions: DRUG: Dalteparin Sodium|DRUG: Tinzaparin Sodium|DRUG: Enoxaparin Sodium|DRUG: Rivaroxaban|DRUG: Apixaban|DRUG: Dabigatran Etexilate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Single-Centre Clinical Trial to Assess Steroid Induced Skin Atrophy on Healthy Skin
Status: COMPLETED
Conditions: Skin and Connective Tissue Diseases
Interventions: DRUG: Clobetasol propionate 0.05 % ointment|DRUG: Betamethasone dipropionate 0.064 % ointment|DRUG: Petrolatum ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Photobiomodulation Therapy for the Management of Breast Cancer-related Lymphedema
Status: RECRUITING
Conditions: Breast Cancer|Breast Cancer Related Lymphedema|Lymphedema of Upper Arm
Interventions: DEVICE: Photobiomodulation therapy (PBMT)|PROCEDURE: Manual Lymphatic drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings Syndrome
Status: TERMINATED
Conditions: Adrenal Tumour With Mild Hypercortisolism
Interventions: PROCEDURE: Adrenalectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Sacubitril/Valsartan in Improving Provider Performance in Managing Heart Failure Under Medicare Alternative Payment Models
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Sacubitril/valsartan|DRUG: ACEI or ARB and no sacubitril/valsartan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Healing of Intra-bony Defects in Modified Minimal Invasive Surgical Technique
Status: COMPLETED
Conditions: Periodontal Regeneration, Clinical and Radiographic Results, Modified Minimal Invasive Surgery
Interventions: PROCEDURE: M-MIST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Irinotecan and Cetuximab With or Without IMC-A12 for Treatment of Participants With Colon or Rectum Cancer Who Got Worse After Their First Treatment With Oxaliplatin and Bevacizumab
Status: TERMINATED
Conditions: Colon Cancer|Rectal Cancer
Interventions: BIOLOGICAL: Cetuximab|DRUG: Irinotecan|BIOLOGICAL: IMC-A12 (cixutumumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neural Mechanisms of Mindfulness-based Cognitive Therapy (MBCT) for PTSD - COVID Related Substudy
Status: COMPLETED
Conditions: Trauma
Interventions: BEHAVIORAL: Mindfulness-Based Cognitive Therapy|BEHAVIORAL: Muscle Relaxation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ixabepilone in Treating Patients With Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 52-Week Parallel Group Safety Study of TD-4208 in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: TD-4208|DRUG: Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lactobacillus Reuteri Strains for Gingivitis Reduction
Status: COMPLETED
Conditions: Gingival Inflammation
Interventions: DIETARY_SUPPLEMENT: L. reuteri (DSM 17938 and ATCC PTA 5289) in form of oral tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repeat Doses Of A New Medication (GW642444) In Asthmatic Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GW642444 (25, 100 & 400 mcg/day)|DRUG: Salmeterol 50mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-level Integration for Patients With Complex Needs Facilitated by ICTs. A Shared Approach, Mutual Learning and Evaluation Are Expected to Create Synergies Among the Partners and to Bring Forward Integration of Care in Europe
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease|Diabetes|Chronic Heart Failure|Frail Elderly Syndrome
Interventions: OTHER: New Care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Microcirculation Properties of Albumin for Fluid Resuscitation in Septic Shock
Status: UNKNOWN
Conditions: Sepsis, Severe|Sepsis|Septic Shock
Interventions: OTHER: 20% Albumin|OTHER: Crystalloid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Monitoring of Femoral Head Perfusion
Status: ENROLLING_BY_INVITATION
Conditions: Femoral Neck Fractures
Interventions: DEVICE: Intracranial pressure (ICP) monitor|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single Dose Administration of Alpha-1 Anti-Trypsin for the Amelioration of Organ Injury in Patients Undergoing Cardiac Surgery
Status: UNKNOWN
Conditions: Post Cardiac Surgery Systemic Inflammatory Response
Interventions: DRUG: Alpha 1-Antitrypsin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HomeStyles-2: Shaping HOME Environments and LifeSTYLES to Prevent Childhood Obesity in SNAP-Education
Status: COMPLETED
Conditions: Healthy Lifestyle|Home Environment Related Disease|Child Behavior|Cognitive Change|Child Obesity|Parenting|Parents|Parent-Child Relations
Interventions: BEHAVIORAL: Healthy HomeStyles|BEHAVIORAL: Eat Healthy Be Active
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of Bone Density in Impacted Mandibular Third Molar
Status: ENROLLING_BY_INVITATION
Conditions: Impacted Third Molar Tooth
Interventions: PROCEDURE: Surgical extraction of impacted third molar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Holmium-166 Micro Brachytherapy in Head and Neck Tumors
Status: TERMINATED
Conditions: Radioisotopes|Head and Neck Neoplasms
Interventions: DEVICE: Holmium-166 (poly L lactic acid) microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proprioception and Sensorimotor Control in Hereditary Sensory and Autonomic Neuropathy
Status: COMPLETED
Conditions: Atunomic Neuropathy
Interventions: OTHER: kinesiology tape around the hip, knee and ankle joints|OTHER: No kinesiology tape around the hip, knee and ankle joints
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Daratumumab in Treating Transplant-Eligible Patients With Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Plasma Cell Myeloma
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|BIOLOGICAL: Daratumumab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motion Sickness Medications and Vestibular Time Constant
Status: UNKNOWN
Conditions: Drug Reaction
Interventions: DRUG: Bonine 25Mg Chewable Tablet|DRUG: Kwells|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Optimized Programming of Healthy Children (APPROACH)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pregnancy|Obesity|Gestational Age and Weight Conditions|Maternal Care for Excessive Fetal Growth|Metabolic Disorders
Interventions: OTHER: High-Protein/Low-GI Diet|OTHER: Low-protein/High-GI Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Role of Mitochondrial-derived Oxidative Stress to Promote Vascular Endothelial Dysfunction in Non-exercisers With Aging
Status: COMPLETED
Conditions: Aging|Endothelial Dysfunction|Cardiovascular Function|Arterial Stiffness
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Mitoquinone Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: CARE-2 (Calcium Acetate [PhosLo®]/Sevelamer[Renagel®] Evaluation Study 2) for Heart Calcification in Dialysis Patients
Status: COMPLETED
Conditions: Calcinosis|Arteriosclerosis|Hyperparathyroidism, Secondary
Interventions: DRUG: calcium acetate|DRUG: sevelamer|DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing the Burden of Influenza After Solid-Organ Transplantation
Status: COMPLETED
Conditions: Influenza|Organ Transplantation
Interventions: BIOLOGICAL: High-dose influenza vaccine|BIOLOGICAL: MF59-adjuvanted influenza vaccine|BIOLOGICAL: Standard intramuscular influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Immunogenicity and Safety of 'BR-TD-1001' Administered Intramuscularly in Healthy Children
Status: COMPLETED
Conditions: Diphtheria|Tetanus
Interventions: BIOLOGICAL: BR-TD-1001|BIOLOGICAL: Td-pur inj
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Osteosarcoma1999-A Study Of Intensive Chemotherapy for Osteosarcoma
Status: COMPLETED
Conditions: Osteosarcoma
Interventions: DRUG: Ifosfamide, Carboplatin, Doxorubicin|PROCEDURE: Limb Sparing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vagus Nerve Stimulation for Systemic Lupus Erythematous
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus|Autonomic Dysfunction|Autonomic Neuropathy|Fatigue
Interventions: DEVICE: Non-invasive transcutaneous vagus nerve stimulation (tVNS)|DEVICE: Sham vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Stem Cells Treatment in Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Type I Diabetes Mellitus With Ulcer|Type II Diabetes Mellitus With Ulcer
Interventions: BIOLOGICAL: ABMD-MSC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Statin on Postoperative Renal Function in Valvular Heart Surgery: a Randomized, Placebo-controlled Study
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: atrovastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Drug-Drug Interaction Study of Abiraterone Acetate Plus Prednisone With Dextromethorphan and Theophylline in Patients With Metastatic Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Neoplasms
Interventions: DRUG: Abiraterone acetate|DRUG: Prednisone|DRUG: Dextromethorphan hydrobromide|DRUG: Theophylline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Qufeng Shengshi Fang on Treatment of Allergic Rhinitis.
Status: UNKNOWN
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: Qufeng Shengshi Fang and Loratadine|DRUG: Loratadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Biophenol-rich Pomegranate Extract Intake on Blood Pressure, Hormones, Body Composition and Quality of Life in Healthy Volunteers.
Status: COMPLETED
Conditions: Cardiovascular Risk Factors
Interventions: DIETARY_SUPPLEMENT: Pomegranate extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy, Safety, pharmacokinetiсs, Immunogenicity of GNR-067 and Lucentis®
Status: RECRUITING
Conditions: Age Related Macular Degeneration (ARMD)
Interventions: BIOLOGICAL: GNR-067|BIOLOGICAL: Lucentis®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess Safety and Efficacy of Topical MBN-101 in Patients With Moderate/ Severe DFI
Status: COMPLETED
Conditions: Diabetic Foot Infection
Interventions: DRUG: MBN-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Technology-Enhanced Executive Functioning Intervention for ADHD
Status: RECRUITING
Conditions: ADHD|Attention Deficit Hyperactivity Disorder|Attention Deficit Disorder|ADD|ADHD Predominantly Inattentive Type|ADHD - Combined Type|ADHD, Predominantly Hyperactive - Impulsive|Attention-Deficit Disorder in Adolescence|Attention-Deficit Hyperactivity Disorder Symptoms|Attention-Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Homework Organization and Planning Skills (HOPS) Intervention|DEVICE: Digital Health Application (Online Platform) for Encouraging Skills Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening With Tampons: Evaluating Diagnostic Accuracy and HPV and Assessing Participant Views
Status: ACTIVE_NOT_RECRUITING
Conditions: Chlamydia|Gonorrhea|Bacterial Vaginosis|Human Papilloma Virus
Interventions: DEVICE: DAYE Diagnostic Tampon|DIAGNOSTIC_TEST: Vaginal self-swab|DIAGNOSTIC_TEST: Clinician vaginal swab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: STUDY TO COMPARE PHARMACOKINETICS (PK) OF SINGLE ORAL DOSES OF DIFFERENT PF-06882961 FORMULATIONS IN PARTICIPANTS WHO ARE OVERWEIGHT OR HAVE OBESITY
Status: COMPLETED
Conditions: Overweight and/or Obesity
Interventions: DRUG: PF-06882961 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating Different Doses of Orelabrutinib in MCL
Status: RECRUITING
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Orelabrutinib High dose|DRUG: Orelabrutinib Low dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide, Fludarabine, Alemtuzumab, and Rituximab (CFAR) for Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Alemtuzumab|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Penumbral Rescue by Normobaric O2 Administration in Patients With Ischemic Stroke and Target Mismatch ProFile
Status: TERMINATED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Medical oxygen|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study to Evaluate the Effects of the Probiotics L. Rhamnosus GR-1 and L. Reuteri RC-14
Status: COMPLETED
Conditions: Vaginosis, Bacterial
Interventions: OTHER: Lactobacillus capsules|DRUG: Placebo gelatin pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of EGF Ointment for the Patients With EGFR-i Related Skin Side Effects
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Pancreatic Cancer|Colorectal Cancer
Interventions: DRUG: Arm EGF ointment 1ppm|DRUG: Arm EGF ointment 20 ppm|DRUG: Arm Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-escalation Trial of the Safety, Pharmacokinetics, and Pharmacodynamics of Iron Isomaltoside (Monofer®)
Status: COMPLETED
Conditions: Anemia|Deficiency Diseases|Anemia, Iron Deficiency|Hematologic Disease|Iron Metabolism Disorders
Interventions: DRUG: Iron Isomaltoside
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abscopal Effect of SBRT in Combination With rhGM-CSF and INF-α 2b for Metastatic Thymic Epithelial Tumors
Status: UNKNOWN
Conditions: Thymic Epithelial Tumor
Interventions: DRUG: rhGM-CSF，Peginterferon alfa-b2，radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CGB-400 Topical Gel for the Treatment of Inflammatory Lesions of Rosacea
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: CGB-400|DRUG: Vehicle Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Monitoring of Cerebral Autoregulation in Perioperative Neonatal Cardiac Surgery
Status: COMPLETED
Conditions: Congenital Heart Disease in Children|Extracorporeal Circulation; Complications
Interventions: PROCEDURE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Detection of Upper Gastrointestinal (GI) Bleeding Using a Novel Bleeding Sensor Capsule -A Pilot Study
Status: COMPLETED
Conditions: Upper Gastrointestinal Bleeding
Interventions: DEVICE: PillSense System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Regenerative Potential of Supercell Glue and Platelet Rich Fibrin Matrix
Status: UNKNOWN
Conditions: Intrabony Periodontal Defect
Interventions: BIOLOGICAL: SUPERCELL GLUE|BIOLOGICAL: PRFM ALONE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: S0802 - Topotecan With or Without Aflibercept in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Extensive Stage Small Cell Lung Cancer|Recurrent Small Cell Lung Cancer
Interventions: BIOLOGICAL: ziv-aflibercept|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cognitive Behavioral Therapy in Patients With Chronic Nonspecific Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain, Mechanical
Interventions: OTHER: Cognitive Behavioral Therapy|OTHER: Home program exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Adaptive Strategy for Preventing and Treating Lapses of Retention in Adult HIV Care (AdaPT-R) in Nyanza, Kenya
Status: COMPLETED
Conditions: HIV
Interventions: BEHAVIORAL: REC; Outreach if Failure|BEHAVIORAL: REC; SMS + Voucher if Failure|BEHAVIORAL: REC; Navigator if Failure|BEHAVIORAL: SMS; Outreach if Failure|BEHAVIORAL: SMS; Outreach if Failure; Stop SMS if Success|BEHAVIORAL: SMS; SMS+Voucher if Failure|BEHAVIORAL: SMS; SMS+Voucher if Failure; Stop SMS if Success|BEHAVIORAL: SMS; Navigator if Failure|BEHAVIORAL: SMS; Navigator if Failure; Stop SMS if Success|BEHAVIORAL: Voucher; Outreach if Failure|BEHAVIORAL: Voucher; Outreach if Failure; Stop Voucher if Success|BEHAVIORAL: Voucher; SMS+Voucher if Failure|BEHAVIORAL: Voucher; SMS+Voucher if Failure; Stop Voucher if Success|BEHAVIORAL: Voucher; Navigator if Failure|BEHAVIORAL: Voucher; Navigator if Failure; Stop Voucher if Success
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication 2.0
Status: RECRUITING
Conditions: Diffuse Intrinsic Pontine Glioma|Diffuse Midline Glioma, H3 K27M-Mutant
Interventions: DRUG: Everolimus|DRUG: ONC201|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Robotic Minimally Invasive Pathway for Cochlear Implantation
Status: COMPLETED
Conditions: Cochlear Hearing Loss|Implant
Interventions: PROCEDURE: cochlear implantation|OTHER: computerized tomography (CT) scan|OTHER: electromyograph
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining the Effects of Virtual Reality Exercise on Mental Health
Status: RECRUITING
Conditions: Mental Health|Mood|Well-Being, Psychological|Physical Activity
Interventions: BEHAVIORAL: Virtual reality exercise condition|BEHAVIORAL: Virtual reality exercise condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Mass Balance and Absolute Bioavailability of GLPG1205
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG1205 film-coated tablets|DRUG: [14C]-GLPG1205 solution for infusion|DRUG: GLPG1205 capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Polyherbal Compound for Control of Blood Sugar in Impaired Glucose Tolerance and Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Polyherbal capsule coccinia, bougainvillea, catharanthus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Terlipressin + Albumin Versus Midodrine + Octreotide in the Treatment of Hepatorenal Syndrome
Status: TERMINATED
Conditions: Cirrhosis|Hepatorenal Syndrome
Interventions: DRUG: Terlipressin plus albumin|DRUG: Midodrine plus octreotide plus human albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emotion Regulation-based Internet-delivered Cognitive Behavioural Therapy for Premenstrual Dysphoric Disorder
Status: NOT_YET_RECRUITING
Conditions: Premenstrual Dysphoric Disorder
Interventions: BEHAVIORAL: Therapist-guided internet-delivered cognitive behavioural therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Persistent Lyme Empiric Antibiotic Study Europe
Status: COMPLETED
Conditions: Lyme Disease|Borrelia Infection
Interventions: DRUG: Doxycycline|DRUG: Clarithromycin and hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of Reflex Plus™ in Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: Reflex Plus|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Using HIV Risk Assessment Tool to Promote HIV Testing Among Men Who Have Sex With Men
Status: UNKNOWN
Conditions: HIV/AIDS|HIV Infections|Social Media
Interventions: BEHAVIORAL: HIV risk assessment and tailored suggestions|BEHAVIORAL: HIV risk behavior assessment|BEHAVIORAL: placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Intra-coronary Infusion of Bone Marrow Derived Autologous CD34+ Selected Cells in Patients With Acute Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction|Coronary Artery Disease
Interventions: DRUG: Intra-coronary infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Ganchero Intervention for Migrant People Who Inject Drugs From Puerto Rico in New York City
Status: NOT_YET_RECRUITING
Conditions: HIV Infections|HCV|Overdose
Interventions: BEHAVIORAL: Ganchero intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Neuroadaptive Cognitive Training in Adolescents at Risk for Psychosis
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Neuroadaptive cognitive training|BEHAVIORAL: Computer games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of MIW815 (ADU-S100) +/- Ipilimumab in Patients With Advanced/Metastatic Solid Tumors or Lymphomas
Status: TERMINATED
Conditions: Advanced/Metastatic Solid Tumors or Lymphomas
Interventions: DRUG: ADU-S100|BIOLOGICAL: ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simultaneous Assessment of Coronary Microvascular Dysfunction and Ischemia With Non-obstructed Coronary Arteries With Intracoronary Electrocardiogram and Intracoronary Doppler
Status: COMPLETED
Conditions: Coronary Microvascular Dysfunction|Coronary Microvascular Disease|Non-Obstructive Coronary Atherosclerosis|Microvascular Angina|Microvascular Coronary Artery Disease|Ischemic Heart Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacogenetic Approach to Anti-platelet Therapy for the Treatment of ST-segment Elevation Myocardial Infarction (STEMI)
Status: COMPLETED
Conditions: STEMI
Interventions: GENETIC: Point-of-Care Genetic Testing|DRUG: Prasugrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OPEN LABEL, 2-PERIOD STUDY, TO COMPARE BIO-AVAILABILITY OF 2 DIFFERENT FORMULATIONS OF PF-05221304 IN HEALTHY ADULTS
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-05221304 Formulation A|DRUG: PF-05221304 Formulation B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: New Prophylactic Maneuver: the "Pushing" Maneuver, Aiming to Reduce the Risk for Shoulder Dystocia
Status: TERMINATED
Conditions: Shoulder Dystocia,|Brachial Plexus Injury|Asphyxia,|Hematoma,|Clavicle Fracture,|Humerus Fracture.
Interventions: PROCEDURE: suctioning of fetal nose and mouth during delivery|PROCEDURE: Pushing maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety and Effectiveness of Drop-free Small Incision Cataract Surgery
Status: UNKNOWN
Conditions: Cataract|Ocular Inflammation|Ocular Hypertension|Post-Op Complication
Interventions: DRUG: Intraoperative delivery of medication, Kenalog (Triamcinolone)|DRUG: Topical post-operative eyedrops, Prednisolone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alemtuzumab and Low-Dose Cyclosporine in Treating Patients With Severe Aplastic Anemia or Acquired Marrow Failure
Status: UNKNOWN
Conditions: Nonmalignant Neoplasm
Interventions: BIOLOGICAL: alemtuzumab|DRUG: cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Finding the Optimal Cooling tempeRature After Out-of-HoSpiTal Cardiac Arrest
Status: COMPLETED
Conditions: Out-Of-Hospital Cardiac Arrest
Interventions: DEVICE: Target Temperature Management of 34°C|DEVICE: Target Temperature Management of 32°C|DEVICE: Target Temperature Management of 33°C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Symptomatic Therapy for Patients With Huntington's Disease
Status: RECRUITING
Conditions: Huntington Disease
Interventions: DRUG: Haloperidol 2Mg Tab|DRUG: Risperidone 1Mg Tab|DRUG: Zoloft 50Mg Tablet|DRUG: Idebenone|DRUG: Deutetrabenazine Oral Tablet [Austedo]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Assessing the Efficacy of Intravenous Iron for the Treatment of Anemia Following Cardiac Surgery
Status: COMPLETED
Conditions: Anemia Postoperative
Interventions: DRUG: Ferric Derisomaltose|DRUG: Ferrous sulfate|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-escalation Study to Evaluate the Safety and Tolerability of GX-I7 in Patients With Glioblastoma
Status: COMPLETED
Conditions: Newly Diagnosed Glioblastoma
Interventions: DRUG: GX-I7
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Association of Sport Nutrition Knowledge and Self-reported Physique Concerns on Eating Behaviours in Elite Athletes Receiving Individualized Sport Nutrition Support
Status: RECRUITING
Conditions: Behavior
Interventions: OTHER: Individualized counselling in nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Tian Ma Bian Chun Zhi Gan Tablets in Mild to Moderate Vascular Dementia
Status: RECRUITING
Conditions: Vascular Dementia|Cognitive Impairment
Interventions: DRUG: Tian Ma Bian Chun Zhi Gan Tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of High Frequency Oscillations With NIV in Hypercapnic COPD Participants
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: BiPAP Synchrony ventilator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Removable Intraductal Stenting in Duct-to-duct Biliary Reconstruction in Liver Transplantation
Status: TERMINATED
Conditions: Transplantation, Liver
Interventions: DEVICE: intraductal removable stent custom-made segment (2 cm)|PROCEDURE: stent extraction by ERCP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: RFA Combined With Chemotherapy for Unresectable Cholangiocarcinoma
Status: COMPLETED
Conditions: Cholangiocarcinoma
Interventions: DEVICE: radiofrequency ablation|DRUG: Chemotherapy drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zonisamide Outpatient Study
Status: WITHDRAWN
Conditions: Post Traumatic Stress Disorder|Alcohol Use Disorder
Interventions: DRUG: Zonisamide|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of the Proposed Test-and-treat Screening Program in Younger Participants With H. Pylori Infection
Status: ENROLLING_BY_INVITATION
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Bismuth Subcitrate|DRUG: Esomeprazole|DRUG: Metronidazole|DRUG: Amoxicillin|DRUG: Clarithromycin|DRUG: Levofloxacin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized, Controlled, Double-blind Clinical Trial of Surinam Cherry Dentifrice With Anti-gingivitis Properties
Status: COMPLETED
Conditions: Gingivitis
Interventions: DRUG: Dentifrice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Influence of Genotype and DDIs of Aspirin on the PK/PD of Clopidogrel and PK of Digoxin
Status: COMPLETED
Conditions: DRUG REACTIONS
Interventions: DRUG: Aspirin+Clopidogrel/Digoxin(oral)|DRUG: Aspirin+Clopidogrel/Digoxin(IV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neurocognitive Outcomes for ICU Patients With Acute Kidney Injury
Status: RECRUITING
Conditions: Delirium|Acute Kidney Injury|Critical Illness|Cognitive Impairment|Cerebral Oxygenation|Cerebral Autoregulation
Interventions: DIAGNOSTIC_TEST: Cerebral oxygenation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Oesophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|DRUG: Oxaliplatin|DRUG: Capecitabine|RADIATION: Radiotherapy|DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: 5-fluorouracil (5-FU)|DRUG: Leucovorin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of Radiation Therapy to Immunotherapy for Merkel Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Merkel Cell Carcinoma|Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8|Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8|Metastatic Merkel Cell Carcinoma|Pathologic Stage III Cutaneous Merkel Cell Carcinoma AJCC v8|Pathologic Stage IIIA Cutaneous Merkel Cell Carcinoma AJCC v8|Pathologic Stage IIIB Cutaneous Merkel Cell Carcinoma AJCC v8|Pathologic Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8
Interventions: BIOLOGICAL: Pembrolizumab|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ramelteon for Sleep Initiation Insomnia in Individuals With Panic Disorder Who Are Also on Escitalopram for Anxiety
Status: TERMINATED
Conditions: Panic Disorder|Insomnia
Interventions: DRUG: Placebo and Escitalopram|DRUG: Ramelteon and Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Plus Capecitabine With Capecitabine Maintenance Treatment in Metastatic Adenocarcinoma of the Stomach or Esophagogastric Junction
Status: UNKNOWN
Conditions: Advanced Gastric Cancer
Interventions: DRUG: Paclitaxel|DRUG: capecitabine|DRUG: capecitabine|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Cisplatin or Carboplatin With Gemcitabine Versus Gemcitabine Alone as Adjuvant Therapy in Patients With Resected or Ablation Intra-Hepatic Cholangiocarcinoma
Status: WITHDRAWN
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Type I Diabetes by Islet Transplantation Into the Gastric Submucosa Study Protocol
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Islet cells|PROCEDURE: Islet transplantation into the gastrointestinal submucosa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnosis of Cardio-Pulmonary Pathology Using Transthoracic Parametric Doppler (TPD)
Status: COMPLETED
Conditions: Lung Disease, Chronic Obstructive|Lung Disease, Interstitial|Asthma|Sarcoidosis|Hypertension, Pulmonary
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Combination Chemotherapy and Surgical Resection in the Treatment of Adrenocortical Carcinoma: Continuous Infusion Doxorubicin, Vincristine and Etoposide With Daily Mitotane Before and After Surgical Resection
Status: COMPLETED
Conditions: Adrenal Cortical Carcinoma
Interventions: DRUG: doxorubicin, vincristine, and etoposide with mitotane
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of the Apatinib Combine With POF Versus POF in Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Adenocarcinoma|Advanced Cancer
Interventions: DRUG: Apatinib|DRUG: POF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Gastro-Intestinal and/or Hepatic Graft Versus Host Disease With Budesonide in Patients Following Peripheral Blood Stem Cell Transplantation
Status: COMPLETED
Conditions: Graft Vs Host Disease
Interventions: DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Novel Mechanics-based Intervention to Improve Post-stroke Stability
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Error reduction|BEHAVIORAL: Error augmentation|BEHAVIORAL: Activity matched control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Acetaminophen in the Intensive Care Unit.
Status: TERMINATED
Conditions: Critical Illness|Fever
Interventions: DRUG: Acetaminophen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Single Injection Femoral Nerve Block With Liposomal Bupivacaine for Total Knee Arthroplasty
Status: WITHDRAWN
Conditions: Total Knee Arthroplasty
Interventions: DRUG: Liposome Bupivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation Training Participated by Caregivers in Ischemic Stroke: a Randomized Controlled Trial to Test the Effect of Home-based Rehabilitation Intervention on Physical Function.
Status: NOT_YET_RECRUITING
Conditions: Ischemic Stroke|Physical Disability
Interventions: BEHAVIORAL: home-based motor rehabilitation training participated by caregivers|BEHAVIORAL: routine self-care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH