pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Combination Study of Deferasirox and Erythropoietin in Patients With Low- and Int-1-risk Myelodysplastic Syndrome.
Status: COMPLETED
Conditions: Low and Int 1-risk Myelodysplastic Syndrome
Interventions: DRUG: Deferasirox DFX, DT|DRUG: Erythropoietin alpha|DRUG: Deferasirox DFX, FCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Relief During IUD Insertion in Women Delivered Only by Elective Cesarean Section
Status: UNKNOWN
Conditions: IUD Insertion Complication
Interventions: DRUG: Misoprostol|DRUG: Placebos|DRUG: isosorbide mononitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mucuna Pruriens Therapy in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: OTHER: MP-Equivalent|OTHER: MP-Low|OTHER: MP+DDCI|DRUG: LD+DDCI|DRUG: LD-DDCI|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Turkish Validity And Reliability Of The Hammersmith Infant Neurological Evaluation (Hine)
Status: COMPLETED
Conditions: Cerebral Palsy|Reliability|Infant Development|Infant, Premature, Diseases|Infant Asphyxia|Validity
Interventions: OTHER: Scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Safety, Efficacy and Pharmacodynamics of Azacitidine in Children and Young Adults With Acute Myeloid Leukemia.
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Azacitidine|OTHER: Control Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin in Treating Children With Recurrent or Refractory Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Randomized, Double-blind, Placebo-controlled Study to Examine the Effects of DAS181 in Immunocompromised Subjects With Lower Respiratory Tract Parainfluenza Infection on Supplemental Oxygen
Status: COMPLETED
Conditions: Parainfluenza
Interventions: DRUG: DAS181 dry powder, formulation F02|DRUG: Lactose Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of 10-valent Pneumococcal Conjugate Vaccine (Pneumosil) Administered in a 2+1 Schedule to Healthy Infants
Status: COMPLETED
Conditions: Pneumonia, Pneumococcal
Interventions: BIOLOGICAL: Pneumosil|BIOLOGICAL: Prevenar 13|BIOLOGICAL: Synflorix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy, Surgery or Radiation Therapy, and Peripheral Stem Cell Transplant in Treating Patients With Recurrent Medulloblastoma or Primitive Neuroectodermal and Pineal Tumors
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: thiotepa|PROCEDURE: conventional surgery|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Adolescent Mothers, Grandmothers, Breastfeeding and Complementary Feeding
Status: COMPLETED
Conditions: Breastfeeding|Weaning
Interventions: BEHAVIORAL: counseling sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating "Real World" Treatment Pattern in Previously Treated Hemophilia A Patients Receiving KOVALTRY (Octocog Alfa) for Routine Prophylaxis
Status: COMPLETED
Conditions: Hemophilia A, Congenital
Interventions: BIOLOGICAL: Kovaltry (Antihemophilic Factor [Recombinant], BAY81-8973
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intranasal Dexmedetomidine Versus Oral Paracetamol as a Pre-anaesthetic Medication in Pediatric Age Group
Status: COMPLETED
Conditions: Anxiety
Interventions: DRUG: Dexmedetomidine|DRUG: paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CT Liver Fat Fraction Quantification
Status: ENROLLING_BY_INVITATION
Conditions: Non-Alcoholic Fatty Liver Disease|Steatosis of Liver
Interventions: DIAGNOSTIC_TEST: Ultra Low Dose CT|DIAGNOSTIC_TEST: Fat quantification MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate Vonoprazan Concentrations in Breast Milk of Healthy Lactating Women Receiving Vonoprazan 20 mg Once Daily or Vonoprazan 20 mg Twice Daily
Status: RECRUITING
Conditions: Erosive Esophagitis|Heartburn|Symptomatic Nonerosive Gasroesophageal Reflux Disease|Helicobacter Pylori Infection
Interventions: DRUG: Vonoprazan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combined Inhibition of PD-1 and DNA Hypomethylating Agent +/- Chemotherapy in High-risk AML or Elderly Patients With AML Who Are Unfit for Intensive Chemotherapy
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia, in Relapsed or Refractory|Acute Myeloid Leukemia, Elderly, Unfit|Acute Myeloid Leukemia With Positive Minimal Residual Disease
Interventions: DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effects of Single Ascending Doses (SAD) of ASP8477, the Effect That Food Has on the Drug, and the Interaction Between ASP8477 and Omeprazole in Healthy Postmenopausal Females and Healthy Young Vasectomized Males
Status: COMPLETED
Conditions: Pharmacokinetics of ASP8477|Pharmacodynamics of ASP8477
Interventions: DRUG: ASP8477|DRUG: omeprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of 12-Week Dietary Intake of Lutein on Minimal Erythema Dose and Other Skin Parameters
Status: COMPLETED
Conditions: Minimal Erythema Dose|Skin Viscoelasticity|Dermis Density
Interventions: DIETARY_SUPPLEMENT: Lutein syrup|DIETARY_SUPPLEMENT: Placebo syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retapamulin Versus Placebo in Secondarily-Infected Traumatic Lesions (SITL)
Status: COMPLETED
Conditions: Skin Infections, Bacterial
Interventions: DRUG: Retapamulin Ointment, 1%|DRUG: Placebo ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BIS-Guided Sedation in Critically Ill Patients Under Deep Sedation
Status: ACTIVE_NOT_RECRUITING
Conditions: Delirium|Sedative Overdose
Interventions: DEVICE: Monitorization of sedation by Bispectral Index
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Compare Neoadjuvant Combination of Trastuzumab and Pertuzumab With Concurrent Taxane Chemotherapy or Endocrine Therapy and Quality of Life Assessment Under Adjuvant Therapy in Operable HER2+/HR+ Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Perjeta Injectable Product|DRUG: Herceptin|DRUG: Tamoxifen|DRUG: Paclitaxel|DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: Anastrozole|DRUG: Letrozole|DRUG: Exemestane|DRUG: Leuprorelin acetate|DRUG: Goserelin|DRUG: Anastrozole|DRUG: Letrozole|DRUG: Exemestane|DRUG: Paclitaxel|DRUG: Tamoxifen|DRUG: Leuporelin acetate|DRUG: Goserelin|DIAGNOSTIC_TEST: Biopsy|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety & Efficacy of Terlipressin vs Octreotide for the Control of Variceal Bleed
Status: COMPLETED
Conditions: Portal Hypertension|Cirrhosis|Hematemesis|Melena
Interventions: DRUG: Terlipressin|DRUG: Octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reproductive Outcome Affected by Two Adjunctive Treatments in Patients With Severe Intrauterine Adhesions
Status: COMPLETED
Conditions: Asherman's Syndrome
Interventions: DEVICE: loop-shaped intrauterine contraceptive device|DEVICE: intrauterine balloon (Cook Medical)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: One Month Daily Wear Clinical Evaluation of New Prototype Contact Lenses in Habitual and Neophyte Contact Lens Wearers
Status: COMPLETED
Conditions: Visual Correction
Interventions: DEVICE: ACUVUE 2|DEVICE: Prototype E1|DEVICE: Prototype E2|DEVICE: Prototype E3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oxygen Consumption After Acute Whole Body Vibration Session
Status: COMPLETED
Conditions: Aged|Oxygen Consumption
Interventions: OTHER: whole body vibration training in vibrating platform in young|OTHER: whole body vibration training in vibrating platform in elderly
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Immunogenicity Study of Live Attenuated Mumps Vaccines in Healthy Infants
Status: COMPLETED
Conditions: Mumps
Interventions: BIOLOGICAL: Investigational live attenuated mumps vaccine|BIOLOGICAL: control live attenuated mumps vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Low-Dose Daunorubicin in Relapsed/Refractory Acute Leukemia
Status: COMPLETED
Conditions: Acute Lymphocytic Leukemia|Acute Myeloid Leukemia
Interventions: DRUG: Daunorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lazertinib (JNJ-73841937) in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lazertinib|DRUG: Midazolam|DRUG: Rosuvastatin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Media, Morphokinetics, and Mosaicism
Status: COMPLETED
Conditions: Embryonic Mosaicism|Embryo Culture Media|Embryo Morphokinetics|Infertility
Interventions: DEVICE: EmbryoScope Plus|OTHER: GLOBAL MEDIA|OTHER: SAGE MEDIA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Monthly Subcutaneous (SC) Mircera for Maintenance Treatment of Participants With Chronic Kidney Disease on Peritoneal Dialysis
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Methoxy polyethylene glycol-epoetin beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of GSK2816126 in Subjects With Relapsed/Refractory Diffuse Large B Cell Lymphoma, Transformed Follicular Lymphoma, Other Non-Hodgkin's Lymphomas, Solid Tumors and Multiple Myeloma
Status: TERMINATED
Conditions: Cancer|Neoplasms
Interventions: DRUG: GSK2816126
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Pharmacokinetic and Pharmacodynamic Properties of FIAsp in Geriatric and Younger Adult Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: Faster-acting insulin aspart|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interleukin-12 and Interleukin-2 in Treating Patients With Mycosis Fungoides
Status: TERMINATED
Conditions: Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Stage I Cutaneous T-cell Non-Hodgkin Lymphoma|Stage I Mycosis Fungoides/Sezary Syndrome|Stage II Cutaneous T-cell Non-Hodgkin Lymphoma|Stage II Mycosis Fungoides/Sezary Syndrome|Stage III Cutaneous T-cell Non-Hodgkin Lymphoma|Stage III Mycosis Fungoides/Sezary Syndrome|Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma|Stage IV Mycosis Fungoides/Sezary Syndrome
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: recombinant interleukin-12|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Hyper-CVAD (Cyclophosphamide, Vincristine, Adriamycin, and Dexamethasone) for Burkitt's and Burkitt's -Like Leukemia/Lymphoma
Status: COMPLETED
Conditions: Burkitt's Lymphoma|Burkitt'S-like Lymphoma
Interventions: DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Dexamethasone|DRUG: G-CSF|DRUG: Cytarabine|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of 2 Fixed Dose Combinations of Linagliptin/Metformin Compared With Single Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 2x500 mg Metformin (Glumetza)|DRUG: 5 mg Linagliptin/1000 mg Metformin FDC|DRUG: 5 mg Linagliptin (Tradjenta)|DRUG: 5 mg Linagliptin (Tradjenta)|DRUG: 3x500 mg Metformin (Glumetza)|DRUG: 5 mg Linagliptin (Tradjenta)|DRUG: 2 x 500 mg Metformin (Glumetza)|DRUG: 5 mg Linagliptin/1000mg Metformin FDC|DRUG: 2 x 2.5 mg Linagliptin/750 mg Metformin FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an Internet-based Intervention for Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: BEHAVIORAL: Exposure for PTSD with cognitive restructuring|BEHAVIORAL: Exposure for PTSD without cognitive restructuring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MK0431/ONO-5435 Phase III Clinical Trial -Add-on to Voglibose Study for Patients With Type 2 Diabetes Mellitus (MK0431-104)
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent
Interventions: DRUG: Comparator: Placebo|DRUG: Sitagliptin|DRUG: Voglibose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Proof Of Concept : Immunogenicity and Safety of hepB Injection in the Dermis Using VAX-ID
Status: COMPLETED
Conditions: Hepatitis B
Interventions: DEVICE: VAX-ID|DRUG: 1.0 cc HBVAXPRO 10mcgr/ml (Sanofi Pasteur MSD)|DRUG: 0.1cc HBVAXPRO 40mcgr/ml (Sanofi Pasteur MSD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Reeducation Program to Effort to Improve the Walking of Multiple Sclerosis Patients
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: OTHER: Effort reeducation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1/2 Trial SRA737 in Combination With Gemcitabine and Cisplatin or Gemcitabine Alone in Advanced Cancer Subjects
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: SRA737, gemcitabine, cisplatin|DRUG: SRA737, gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasotracheal Intubation Using Shikani Optical Stylet
Status: COMPLETED
Conditions: Intubation; Difficult
Interventions: PROCEDURE: Nasotracheal Intubation through seeing optical stylet (SOS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention Program- Promoting Self Resilience, Positive Self-Image and Body Image Among Adolescents and Their Parents
Status: COMPLETED
Conditions: Primary Prevention
Interventions: BEHAVIORAL: Experimental: Prevention Program "young In Favor of Myself", active parents|BEHAVIORAL: Experimental: Prevention Program "young In Favor of Myself", no parental involvement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Biological Modulation of Bacterial QSSMs, Innate and Adaptive Immunity by Antibiotics, Probiotics and Prebiotics in Healthy Individuals
Status: COMPLETED
Conditions: Quorum Sensing|Prebiotics|Probiotics|Sepsis
Interventions: DIETARY_SUPPLEMENT: Bifidobacterium longum BB536|DIETARY_SUPPLEMENT: Active hexose correlated compound (AHCC)|DIETARY_SUPPLEMENT: Bifidobacterium longum BB536 and Active hexose correlated compound (AHCC)|DIETARY_SUPPLEMENT: Corn starch placebo capsule|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Skin-to-skin Contact on Interaction and Parents' Sleep
Status: TERMINATED
Conditions: Sleep Quality|Communication|Stress Reaction
Interventions: BEHAVIORAL: Continuous skin-to-skin contact|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Percutaneous Edge To Edge Repair for the Treatment of Severe Tricuspid Valve Regurgitation in High-surgical Risk Patients With Systemic Right Ventricle : a Multicentric French Cohort (PETER-TRESRIV)
Status: UNKNOWN
Conditions: Systemic Right Ventricle|Tricuspid Regurgitation|Congenital Heart Disease
Interventions: DEVICE: Edge to edge repair in systemic tricuspid valve regurgitation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Feasibility of the Branched TAG® Device in the Treatment of Aortic Arch Aneurysms
Status: COMPLETED
Conditions: Aneurysm of Aortic Arch
Interventions: DEVICE: GORE® TAG® Thoracic Branch Endoprosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effectiveness and Safety Comparison of Lunaphil Ultra (Hyaluronic Acid, by Espad Pharmed Co.) Versus Juvederm Ultra 4® (Hyaluronic Acid, by Allergan Co.) in Nasolabial Folds (NLFs) Management
Status: COMPLETED
Conditions: Moderate or Severe Nasolabial Folds
Interventions: DEVICE: Hyaluronic acid Lunaphil Ultra (by Espad Pharmed Co.)|DEVICE: Hyaluronic acid Juvederm Ultra 4® (by Allergan Co.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution in Children and Adults With Epileptic Encephalopathy Including Dravet Syndrome and Lennox-Gastaut Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Dravet Syndrome|Lennox Gastaut Syndrome|Epileptic Encephalopathy
Interventions: DRUG: ZX008 (Fenfluramine Hydrochloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus
Status: TERMINATED
Conditions: Advanced Solid Tumor
Interventions: DRUG: Pimasertib|DRUG: Pimasertib|DRUG: Temsirolimus|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PembROlizumab With or Without Microbial EcOsystem ThErapeutic 4 (MET4) in Advanced Head and Neck Squamous Cell Carcinoma
Status: WITHDRAWN
Conditions: Advanced Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Pembrolizumab|DRUG: MET-4|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Pre-administered Natural Sweet-tasting Solution (Honey) for Decreasing Pain of Needle Insertion
Status: NOT_YET_RECRUITING
Conditions: Analgesia
Interventions: DIETARY_SUPPLEMENT: honey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 3BNC117-LS First-in-Human Phase 1 Study
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: DRUG: 3BNC117-LS|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vancomycin Tissue Concentrations by Bier Block or Intravenous Administration
Status: COMPLETED
Conditions: Infection|Hand Injury Wrist|Hand Injuries|Hand Injuries and Disorders|Hand Arthritis
Interventions: DRUG: Systemic IV Vancomycin|PROCEDURE: Bier Block|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Caloric Vestibular Stimulation for Modulation of Insight in Obsessive-Compulsive Spectrum Disorders
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder|Body Dysmorphic Disorders|Illness Anxiety Disorder
Interventions: OTHER: Caloric Vestibular Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects Of Post Isometric Relaxation And Post Facilitation Stretching On ROM, Pain And Functional Limitations
Status: UNKNOWN
Conditions: Erector Spinae Tightness
Interventions: OTHER: POST ISOMETRIC RELAXATION|OTHER: POST FACILITATION STRETCHING
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy Assessment of an Automatic Blood Pressure Measurement Device in Adult Volunteers
Status: COMPLETED
Conditions: Pre Eclampsia
Interventions: DEVICE: Sphygmo: Automatic Blood Pressure Monitor|DEVICE: GE Dinamap ProCare Automatic Blood Pressure Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Oral Administration of Tranexamic Acid in Anterior Cruciate Ligament Surgery Reduce Postoperative Haemarthrosis
Status: UNKNOWN
Conditions: Hemorrhage Postoperative|Anterior Cruciate Ligament Rupture|Arthroscopy|Total Blood Loss
Interventions: DRUG: Oral tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clazakizumab for Chronic and Active Antibody Mediated Rejection Post-Kidney Transplant
Status: COMPLETED
Conditions: Antibody-mediated Rejection|Kidney Transplant; Complications|Transplant Glomerulopathy|Transplant Glomerulopathy - Late Form|Transplant Glomerulopathy - Early Form|Kidney Transplant Rejection
Interventions: DRUG: Clazakizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Xaliproden on Recovery Rate From Severe Neuropathy in Patients Who Have Completed Adjuvant Chemotherapy With Oxaliplatin Based Regimens
Status: TERMINATED
Conditions: Colorectal Neoplasms
Interventions: DRUG: Placebo|DRUG: Xaliproden
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic Decompression of the Pudendal Nerve in Pudendal Neuralgia
Status: TERMINATED
Conditions: Robotic Decompression
Interventions: PROCEDURE: Robotic laparoscopic decompression of pudendal nerve entrapment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Association of Cigarette Smoking on Exercise Capacity and Skeletal Muscle Function in Taiwan Adult Smokers
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: DEVICE: Body Composition|DEVICE: Heart rate variability|DEVICE: Grip Strength|DEVICE: Exhale Carbon Monoxide Concentration|DEVICE: Pulmonary Function Test|DEVICE: Respiratory Muscle Function|BEHAVIORAL: Fagerström Test for Nicotine Dependence|BEHAVIORAL: Seven-Day Physical Activity Recall Questionnaire|DEVICE: Cardiopulmonary exercise testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clears On the Day of Anesthesia Permissible up to One-Hour Prior (CODA-POP) to Surgery
Status: NOT_YET_RECRUITING
Conditions: Perioperative Nutrition
Interventions: OTHER: Clear Liquids|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Telerehabilitation and Face-to-face Rehabilitation on COVID-19 Survivors
Status: COMPLETED
Conditions: Covid19|Exercise Tolerance|Quality of Life|Lung Function|Fatigue Intensity
Interventions: OTHER: Face-to-face rehabilitation|OTHER: Telerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of PF-04449913 In Japanese Patients With Select Hematologic Malignancies
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: PF-04449913|DRUG: PF-04449913|DRUG: Low dose ARA-C (LDAC)|DRUG: PF-04449913|DRUG: Daunorubicin|DRUG: Cytarabine|DRUG: PF-04449913|DRUG: Azacitidine|DRUG: PF-04449913|DRUG: LDAC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MAGE A10ᶜ⁷⁹⁶T for Advanced NSCLC
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer|Carcinoma
Interventions: BIOLOGICAL: Autologous Genetically modified T cells, MAGEA10ᶜ⁷⁹⁶T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Ergogenic Potential and Risks Associated With Acute and Chronic Use of Sulphonylureas on Physical Exercise
Status: UNKNOWN
Conditions: Resistance Training|Sport Performance|Muscle Recovery|Hypoglycemic Agents|Randomized Controlled Trial
Interventions: OTHER: Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effects Of Methacholine Challenge Administered Using Three Different Nebulizers On Small Airways Function
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: 1. Wright Nebulizer|OTHER: Pari LC Nebulizer|OTHER: The Pari Sinustar Nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Peri-Implant Soft and Hard Tissue Stability Following Socket Preservation
Status: COMPLETED
Conditions: Alveolar Ridge Augmentation|Bone Transplantation
Interventions: PROCEDURE: Socket Preservation with Platelet-Rich Fibrin|PROCEDURE: Socket Preservation with Freeze-Dried Bone Allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III, Randomised, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of TD0069 Capsule for Patients With Mild to Moderate COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: TD0069 hard capsule|DRUG: TD0069 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Open-label, Study of Pazopanib in Combination With Gemcitabine and Gemcitabine Plus Cisplatin for Advanced Solid Tumors
Status: COMPLETED
Conditions: Lung Cancer, Non-Small Cell
Interventions: DRUG: Pazopanib (GW786034)|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Difference Between Rehabilitation Therapy and Stem Cells Transplantation in Patients With Spinal Cord Injury in China
Status: UNKNOWN
Conditions: Spinal Cord Injuries
Interventions: PROCEDURE: rehabilitation of limb function|PROCEDURE: Stem Cells Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Global Study of Volrustomig (MEDI5752) Plus Chemotherapy Versus Pembrolizumab Plus Chemotherapy for Participants With Metastatic Non-small Cell Lung Cancer.
Status: RECRUITING
Conditions: Metastatic Non-small Cell Lung Cancer
Interventions: DRUG: Volrustomig|DRUG: Pembrolizumab|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Repigmentation After Epidermal Cell Suspension Grafting and preVENTing the Loss of Melanocytes Using Topical Ruxolitinib for Vitiligo in Resistant Areas
Status: ACTIVE_NOT_RECRUITING
Conditions: Vitiligo
Interventions: DRUG: Ruxolitinib Topical|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of LycoRed Phytonutrient and Vitamin Supplement (a.k.a. LYC-001e) on Ocular Blood Flow
Status: COMPLETED
Conditions: Ocular Blood Flow
Interventions: DIETARY_SUPPLEMENT: Experimental|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of Intravenous Rate Control Response in Atrial Fibrillation Trial (AIRCRAFT)
Status: WITHDRAWN
Conditions: Atrial Fibrillation
Interventions: DRUG: Beta-blocker strategy|DRUG: Calcium channel blocker strategy|DRUG: Physician preference strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effects of Spirulina Platensis on Insulin Resistance in HIV-infected Patients
Status: COMPLETED
Conditions: Insulin Resistance|HIV/AIDS
Interventions: DIETARY_SUPPLEMENT: Spirulina platensis|DIETARY_SUPPLEMENT: Soya bean
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combined Neuromodulation and Cognitive Training for Post-mTBI Depression
Status: RECRUITING
Conditions: Depression|Mild Traumatic Brain Injury|Concussion, Brain
Interventions: DEVICE: iTBS|DEVICE: sham iTBS|BEHAVIORAL: Personalized, Augmented Cognitive Training (PACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Osteopathic Manipulative Treatment on Pain in Preterms
Status: UNKNOWN
Conditions: Prematurity
Interventions: OTHER: Osteopathic manipulative treatment|OTHER: Sham therapy|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin Type A (BT-A) in Hemiplegic Shoulder Pain Versus Steroid
Status: UNKNOWN
Conditions: Stroke|Hemiparesis|Shoulder Pain
Interventions: DRUG: BT-A (Dysport 500U), Triamcinolone acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Vitamin A Value of Spirulina Carotenoids in Humans
Status: COMPLETED
Conditions: Intrinsically Labeled Spirulina
Interventions: DIETARY_SUPPLEMENT: spirulina ß-carotene|DIETARY_SUPPLEMENT: spirulina ß-carotene
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I Study of Interperitoneal Chenotherapy in Patients With Gastric Adenocarainoma With Peritoneal Seeding
Status: COMPLETED
Conditions: Stomach Neoplasms
Interventions: DRUG: irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Controlled Breathing Course for Social & Emotional Health for Vietnam Veterans With Chronic PTSD-RCT
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Sudarshan KRIYA Breathing Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: ECT
Clinical trial: Effects of Adherence Therapy on Medication Adherence in Patients With Schizophrenia Spectrum Disorder
Status: COMPLETED
Conditions: Motivational Interviewing|Schizophrenia Spectrum Disorder|Medication Adherence
Interventions: BEHAVIORAL: Adherence Therapy|BEHAVIORAL: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture Treatment for Gastroparesis: a Pilot Study
Status: COMPLETED
Conditions: Gastroparesis|Nausea|Vomiting|Abdominal Pain
Interventions: PROCEDURE: Acupuncture for gastroparesis|PROCEDURE: Acupuncture for musculoskeletal pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Adapting Personality-Targeted Interventions for Reducing Substance Misuse and Related Outcomes in Youth in Youth Protection Services
Status: COMPLETED
Conditions: Substance Use Disorders|Youth Protection Services|Early Intervention|Prevention|Adolescent Development
Interventions: BEHAVIORAL: Personality-targeted Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ondansetron, Alcohol Use, and Alcohol-Related Symptoms In HIV+ Persons
Status: COMPLETED
Conditions: Alcohol Abuse|Alcohol Dependence
Interventions: DRUG: ondansetron|DRUG: placebo ondansetron|DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Misoprostol Versus Effox as Cervical Ripening Agent Prior Surgical Evacuation
Status: UNKNOWN
Conditions: Cervical Ripening
Interventions: DRUG: Misoprostol|DRUG: Isosorbide-5-mononitrate|DRUG: misoprostol and Isosorbide-5-mononitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Omega 3/6 Fatty Acids for Reading in Children
Status: COMPLETED
Conditions: Reading Ability
Interventions: DIETARY_SUPPLEMENT: Omega 3/6 fatty acids|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Licorice on Reducing Salivary Streptococcus Mutans Versus Chlorohexidine in Caries Risk Patients
Status: UNKNOWN
Conditions: Caries, Dental
Interventions: OTHER: licorice extract mouthwash|OTHER: chlorohexidine mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Association With Low Compliance Bladder in Women With LUTS
Status: NOT_YET_RECRUITING
Conditions: Urinary Bladder, Overactive|Urinary Bladder Neck Obstruction|Pelvic Organ Prolapse|Urinary Incontinence
Interventions: DRUG: medical treatment for lower urinary tract symptoms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adaptations to Breast Cancer and Exercise Using Telehealth (ABRACE: Telehealth)
Status: UNKNOWN
Conditions: Breast Cancer Female
Interventions: OTHER: Multicomponent exercise intervention plus health education|OTHER: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Acute-phase Response & Periodontal Treatment in Obese Patients
Status: COMPLETED
Conditions: Periodontal Diseases|Obesity
Interventions: PROCEDURE: FM-SRP|PROCEDURE: Q-SRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: WHNRC (Western Human Nutrition Research Center) Fiber Intervention Study
Status: RECRUITING
Conditions: Inflammation|Vaccine|Intestinal Permeability|Typhoid Fever
Interventions: DIETARY_SUPPLEMENT: Inulin|DIETARY_SUPPLEMENT: Maltodextrin|BIOLOGICAL: Ty21a Typhoid Fever Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Better Understanding of Fatigue After STroke
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: DIAGNOSTIC_TEST: ECG|DIAGNOSTIC_TEST: Transthoracic echography (TTE)|DIAGNOSTIC_TEST: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: PS101-mediated ACT With Chemotherapy in Liver Metastases From Cancer of Gastrointestinal Origin
Status: RECRUITING
Conditions: Solid Tumor|Colorectal Cancer
Interventions: DRUG: 20 uL/kg PS101|DRUG: 40 uL/kg PS101|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serratus Anterior Plane Block Versus Erector Spinae Plane Block. for Thoracotomy in Pediatric Patients
Status: RECRUITING
Conditions: Anesthesia
Interventions: PROCEDURE: Fascial plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-DOPA-PET in Finding Tumors in Patients With Newly Diagnosed Gliomas Undergoing Radiation Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Glioma
Interventions: PROCEDURE: Diffusion Weighted Imaging|DRUG: Fluorine F 18 Fluorodopa|RADIATION: Intensity-Modulated Radiation Therapy|PROCEDURE: Perfusion Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|OTHER: Quality-of-Life Assessment|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ghrelin in Cystic Fibrosis
Status: UNKNOWN
Conditions: Cystic Fibrosis
Interventions: BIOLOGICAL: ghrelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pragmatic Trial Comparing Symptom-Oriented Versus Routine Stress Testing in High-Risk Patients Undergoing Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Coronary Artery Disease With Myocardial Infarction
Interventions: DIAGNOSTIC_TEST: routine stress testing|DIAGNOSTIC_TEST: No Routine stress testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multifocal Intraocular Lens x Monovision x Hybrid Monovision After Bilateral Cataract Surgery
Status: COMPLETED
Conditions: Cataract|Presbyopia
Interventions: PROCEDURE: Cataract surgery with intraocular lens implantation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Tislelizumab in Combination With Chemotherapy Compared to Chemotherapy Alone for Participants With Urothelial Carcinoma
Status: RECRUITING
Conditions: Urothelial Carcinoma
Interventions: DRUG: Tislelizumab|DRUG: Placebo|DRUG: Cisplatin|DRUG: Gemcitabine Hydrochloride|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sevoflurane-remifentanil EC50 (The 50% Effective Concentration) Values for LMA-Supreme Versus LMA ProSeal Insertion
Status: COMPLETED
Conditions: Sevoflurane
Interventions: DEVICE: laryngeal mask supreme|DEVICE: laryngeal mask proseal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Latanoprost and Bimatoprost Solutions in Promoting Eyelash Growth in Patients With Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: Latanoprost (Xalatan)|DRUG: Bimatoprost (Lumigan)|DRUG: Topical application of latanoprost solution to eyelid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VICTOR - Avelox® Intravenous (i.v.) in Acute Exacerbations of Chronic Bronchitis
Status: COMPLETED
Conditions: Chronic Bronchitis|Disease Exacerbation
Interventions: DRUG: Moxifloxacin (Avelox, BAY12-8039)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effectiveness of Mini-fluid Challenge in Predicting Fluid Responsiveness During Video Assisted Thoracic Surgery
Status: UNKNOWN
Conditions: Mini-fluid Challenge in Video-Assisted Thoracic Surgery
Interventions: DRUG: Crystalloid Solutions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Increasing Use of Earned Income Tax Credit (EITC) in New Mexico
Status: COMPLETED
Conditions: Adverse Childhood Experiences
Interventions: OTHER: EITC & ACEs Training|OTHER: EITC Outreach & Screening|OTHER: Assistance with EITC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pain Neuroscience Education Following Arthroscopic Rotator Cuff Repair
Status: COMPLETED
Conditions: Rotator Cuff Injuries|Tear|Pain, Shoulder
Interventions: OTHER: Pain neuroscience education|OTHER: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Clinical Investigation to Evaluate Clinical Performance, Safety and Patient Reported Outcomes of an Active Osseointegrated Steady-State Implant System
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Active Osseointegrated Steady-State Implant System (OSI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CLINICAL PROTOCOL to Investigate the Long-term Safety and Efficacy of Metreleptin in Various Forms of Partial Lipodystrophy
Status: COMPLETED
Conditions: Familial Partial Lipodystrophy|Nonalcoholic Steatohepatitis|NAFLD
Interventions: DRUG: Metreleptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Bioequivalence Between Ticagrelor Orodispersible Tablets and Ticagrelor Immediate-release Tablets in Japanese Subjects
Status: COMPLETED
Conditions: Bioequivalence|Healthy Japanese Subjects|Pharmacokinetics
Interventions: DRUG: Ticagrelor OD tablet (90 mg single dose) administered with 150 mL of water|DRUG: Ticagrelor OD tablet (90 mg single dose) administered without water|DRUG: Ticagrelor IR tablet (90 mg) administered with 150 mL of water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Behavioral Economics Incentives to Support HIV Treatment Adherence in Sub-Saharan Africa
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: BEHAVIORAL: Incentivization based on high adherence|BEHAVIORAL: Incentivization based on timely clinic visit|BEHAVIORAL: Annual adherence prize drawing|BEHAVIORAL: Annual viral suppression-based prize drawing|BEHAVIORAL: Year 2 booster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of McCune-Albright Syndrome
Status: COMPLETED
Conditions: Nervous System Disease
Interventions: OTHER: Brain PET Imaging with 11C Rolipram|DRUG: Whole Body PET Baseline with 11C Rolipram|DRUG: Whole Body PET Blocked with Roflumilast
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE