pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Prevelance Of Cutaneous Disorders Among Patients With Heamatologic Malignancies
Status: NOT_YET_RECRUITING
Conditions: Dermatologic Disorders With Heamatologic Malignancies Patients
Interventions: DIAGNOSTIC_TEST: cbc ,u\s renalor hepatic function test if needed
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Ultrasound Guided Versus Land-mark Location Method for Performing Spinal Anesthesia in Obese Parturients
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: PROCEDURE: Ultrasound group|PROCEDURE: Landmark group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of CC-90006 in Subjects With Mild to Moderate Plaque-type Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: CC-90006|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple-dose Study of ASP8374, an Immune Checkpoint Inhibitor, as a Single Agent and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: ASP8374|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simultaneous Integrated Boost FDOPA Positron Emission Tomography (PET) Guided in Patients With Partially- or Non-operated Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma Multiforme, Adult
Interventions: PROCEDURE: Integrated boost technique (SIB) guided by PET FDOPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Modified Limb Braking and Early Bed Mobility Strategies After Femoral Venipuncture Intervention
Status: NOT_YET_RECRUITING
Conditions: Deep Vein Thrombosis|Deep Venous Insufficiency
Interventions: OTHER: Reduced postoperative braking and bed rest time.Lower extremity on the puncture side with a 2-hour brake+Get out of bed after 4 hours|OTHER: Significantly reduce postoperative braking and bed rest time.No braking of the lower limb on the side of the puncture+Get out of bed after 2 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of BIIB131 for Participants With Ischemic Stroke Between 4.5 and 24 Hours After Last Known Well
Status: WITHDRAWN
Conditions: Ischemic Stroke
Interventions: DRUG: BIIB131|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetic Profile of ABN401 in Patients With Advanced Solid Tumors Harboring c-MET Dysregulation
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: ABN401
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Head Mount Display-based Virtual Reality Rehabilitation of Hemispatial Neglect
Status: COMPLETED
Conditions: Stroke|Neglect, Hemispatial
Interventions: DEVICE: field of regard-focused visual exploration therapy|OTHER: conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modeling Tobacco Regulatory Impacts in Appalachia Using the Experimental Tobacco Marketplace
Status: ENROLLING_BY_INVITATION
Conditions: Tobacco Use|Cigarette Use
Interventions: DRUG: Very Low Nicotine Cigarette|BEHAVIORAL: Reduced nicotine regulatory environment|BEHAVIORAL: Restriction on characterizing flavors in combustible nicotine products|BEHAVIORAL: Restriction on characterizing flavors in noncombustible nicotine products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Ultra - Brief Crisis IPT-A Based Intervention for Suicidal Children and Adolescents (IPT-A-SCI)
Status: UNKNOWN
Conditions: Suicide, Attempted
Interventions: OTHER: IPT A Suicide Crisis Intervention|OTHER: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study With [225Ac]Ac-FL-020 in mCRPC Participants
Status: NOT_YET_RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: [225Ac]Ac-FL-020|DRUG: Blood samples for PK|DRUG: [111In]In-FL-020|PROCEDURE: Blood and urine samples collection|PROCEDURE: SPECT/CT images
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of INGAP-Peptide in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent
Interventions: DRUG: INGAP-Peptide|DRUG: INGAP-Peptide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) Immune Kidney Transplant Study (COVID-19)
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Transplant Infection|SARS-CoV Infection
Interventions: DRUG: SARS-CoV-2 vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sars-CoV-2/COVID-19 Ivermectin Navarra-ISGlobal Trial
Status: COMPLETED
Conditions: Covid-19|Coronavirus Infection|SARS-CoV-2 Infection
Interventions: DRUG: Ivermectin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prolotherapy for the Treatment of Chronic Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis|Tennis Elbow
Interventions: DRUG: Prolotherapy|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Irisin Levels in Patients With Charcot-Marie-Tooth (CMT) Disease
Status: COMPLETED
Conditions: Charcot-Marie-Tooth Disease
Interventions: DIAGNOSTIC_TEST: Bioimpedenziometry, Handgrip strenght evaluation|DIAGNOSTIC_TEST: Evaluation on blood specimens
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Serological Test s for the Virus Chicken Pox Virus (VZV) and Correlation With the Patient's Memory of the Infection or Vaccination
Status: TERMINATED
Conditions: Pregnancy
Interventions: BIOLOGICAL: Serological Test s for the Virus Chicken Pox Virus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of ISOPURE and EYHANCE (Switzerland)
Status: RECRUITING
Conditions: Cataract|Lens Opacities
Interventions: DEVICE: IOL implantation experimental (ISOPURE 1.2.3.)|DEVICE: IOL implantation active comparator (TECNIS Eyhance)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nitrous Oxide for Analgesia During Office Urethral Bulking
Status: TERMINATED
Conditions: Pain|Stress Incontinence, Female
Interventions: DRUG: Nitrous Oxide + Oxygen Gas (Product)|DRUG: lidocaine gel 2%|OTHER: Room air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Efficacy of a Bioengineered Corneal Implant for Treatment of Keratoconus
Status: UNKNOWN
Conditions: Keratoconus
Interventions: DEVICE: LinkCor Bioengineered Corneal Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Flexible Intubating Stylet in the Accurate Placement of Double-lumen Endobronchial Tube
Status: COMPLETED
Conditions: Intubation Complication|Intubation, Difficult
Interventions: DEVICE: Tranditional fiberoptic bronchoscopy|DEVICE: Modified fiberoptic bronchoscopy|DEVICE: Flexible Trachway intubating stylet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 24 Week Trial to Compare the Efficacy and Safety of Delgocitinib Cream 20 mg/g Twice-daily With Alitretinoin Capsules Once-daily in Adult Participants With Severe Chronic Hand Eczema
Status: COMPLETED
Conditions: Chronic Hand Eczema
Interventions: DRUG: Delgocitinib|DRUG: Toctino
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Daylight Photodynamic Therapy for the Treatment of Actinic Keratoses in the Northeast United States
Status: WITHDRAWN
Conditions: Actinic Keratosis|Non-melanoma Skin Cancer
Interventions: DRUG: aminolevulinic acid HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Burst Crossover Trial
Status: RECRUITING
Conditions: Back Pain With Radiation|Pain, Postoperative
Interventions: PROCEDURE: Burst Spinal Cord Stimulation|PROCEDURE: Sham spinal cord stimulation|DEVICE: SCS implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation (tDCS) As A Tool For Prospective Responder Identification Before Vagus Nerve Stimulation (VNS) Implantation
Status: UNKNOWN
Conditions: Epilepsy
Interventions: PROCEDURE: transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: One Year Home Monitoring and Treatment of IBS Patients
Status: UNKNOWN
Conditions: eHealth|Dietary Modification|Probiotics|Microbiome|Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Low FODMAP diet (LFD)|DIETARY_SUPPLEMENT: VSL#3®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Stem Cell Transplant for Refractory Crohn's Disease
Status: WITHDRAWN
Conditions: Crohn's Disease
Interventions: DRUG: mobilization of stem cells to prepare for Leukapheresis|OTHER: Leukapheresis- Collection of stem cells|DRUG: Preparative regimen 4-6 weeks after Leukapheresis|OTHER: Stem Cell Transplant|DRUG: Low-dose IL-2 administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Control Following Third Molar Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Post Operative Pain|Impacted Third Molar Tooth
Interventions: DRUG: Paracetamol and Ibuprofen. The combination of the Paracetamol and Ibuprofen will be given together every 8 hours|DRUG: Paracetamol and Ibuprofen. The combination of the Paracetamol and Ibuprofen will be given alternatively every four hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Explore the Safety, Tolerability and Efficacy of MK-3475 in Combination With INCB024360 in Participants With Selected Cancers
Status: COMPLETED
Conditions: Microsatellite-instability (MSI) High Colorectal Cancer (CRC)|Endometrial Cancer|Head and Neck Cancer|Hepatocellular Carcinoma (HCC)|Gastric Cancer|Lung Cancer|Lymphoma|Renal Cell Carcinoma (RCC)|Ovarian Cancer|Solid Tumors|UC (Urothelial Cancer)|Melanoma|Bladder Cancer|Triple Negative Breast Cancer (TNBC)
Interventions: DRUG: MK-3475|DRUG: INCB024360
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Vildagliptin as add-on Therapy to Metformin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Vildagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Demonstrating The Effect Of Latanoprost In Combination With Timolol, Latanoprost Alone And Timolol Alone On Eye Pressure In Open Angle Glaucoma Or Ocular Hypertension In Patients
Status: COMPLETED
Conditions: Ocular Hypertension|Glaucoma|Open-angle Glaucoma
Interventions: DRUG: i. Fixed combination of latanoprost 0.005% and timolol 0.5%|DRUG: timolol 0.5% ophthalmic solution|DRUG: latanoprost 0.005% ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Ischaemic Preconditioning in Transplantation (RIPTRANS)
Status: RECRUITING
Conditions: Transplant Dysfunction
Interventions: PROCEDURE: RIPC|PROCEDURE: Sham-RIPC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MDCO-2010 in Patients Undergoing Elective Coronary Artery Bypass Graft Surgery
Status: COMPLETED
Conditions: Coronary Artery Bypass Graft|Cardiopulmonary Bypass
Interventions: DRUG: MDCO-2010|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erlotinib Versus Gemcitabine/Cisplatin as (Neo)Adjuvant Treatment in Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Erlotinib|DRUG: Gemcitabine/cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parenteral Hydration in Advanced Cancer Patients
Status: COMPLETED
Conditions: Advanced Cancer|Dehydration
Interventions: DRUG: Saline|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of TRU-015 in Subjects With Membranous Nephropathy Secondary to Systemic Lupus Erythematosus
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: TRU-015
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A PRospective, rAndomizEd Comparison of subcuTaneOous and tRansvenous ImplANtable Cardioverter Defibrillator Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Ventricular Arrhythmias
Interventions: DEVICE: Implantation of subcutaneous ICD|DEVICE: Implantation of transvenous ICD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytokine Assay in Tears of Healthy Children and With Vernal Keratoconjunctivitis: Case Control Study and Monitoring of Cases at 6 Months
Status: UNKNOWN
Conditions: Vernal Keratoconjunctivitis|Healthy Children
Interventions: PROCEDURE: Cytokins assay in tears
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nitrous Oxide On Acute Postoperative Pain and Opioid Consumption and Chronic Pain After Inguinal Hernia Repair Surgery
Status: WITHDRAWN
Conditions: Inguinal Hernia Repair|Post Operative Pain
Interventions: DRUG: Nitrous Oxide|OTHER: oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Of PF-03463275 As Add-On Therapy In Outpatients With Persistent Negative Symptoms Of Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: PF-03463275|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intense Pulsed Light Therapy for Hidrosadenitis Suppurativa
Status: UNKNOWN
Conditions: Hidradenitis Suppurativa|Acne Inversa
Interventions: OTHER: IPL laser|OTHER: No sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity, Life Satisfaction and Medication Adherence in Older Adults
Status: COMPLETED
Conditions: Physical Activity|Life Satisfaction|Medication Adherence|Older Adults
Interventions: OTHER: Asessment|OTHER: The Physical Activity Scale for the Elderly (PASE)|OTHER: Turkish Version of the Satisfaction with Life Scale (T-SWLS)|OTHER: Modified Morisky Scale (MMS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Capillaroscopy on the Management of Undifferentiated Connective Tissue Disease
Status: RECRUITING
Conditions: Undifferentiated Connective Tissue Diseases
Interventions: DIAGNOSTIC_TEST: Nail capillaroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: mHealth Mood Management Tool (Actify) to Improve Population-Level Smoking Cessation
Status: COMPLETED
Conditions: Cigarette Smoking-Related Carcinoma
Interventions: OTHER: Health Promotion and Education|BEHAVIORAL: Smoking Cessation Intervention (Actify app)|BEHAVIORAL: Smoking Cessation Intervention (Current Standard Care app)|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Supplemental Benefit of Angiotensin Receptor Blocker in Hypertensive Patients With Stable Heart Failure Using Olmesartan
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: DRUG: olmesartan medoxomil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palliation of Dyspnea With Morphine in Patients With Interstitial Lung Disease
Status: COMPLETED
Conditions: Interstitial Lung Disease|Dyspnea|Morphine
Interventions: DRUG: Morphine hydrochloride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Vemurafenib, Carboplatin, and Paclitaxel
Status: COMPLETED
Conditions: Advanced Cancers
Interventions: DRUG: Vemurafenib|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glycemic and Insulinemic Impact of a Test Granola 2 Versus a Control Granola
Status: COMPLETED
Conditions: Glycemic Response|Insulinemic Response|Subject Hunger Response
Interventions: OTHER: Test Granola|OTHER: Control Granola
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PROCHYMAL™ (Human Adult Stem Cells) for the Treatment of Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Pulmonary Emphysema|Chronic Bronchitis
Interventions: DRUG: Prochymal™|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bupivacaine or Radiofrequency for Shoulder Pain
Status: COMPLETED
Conditions: Shoulder Pain|Rotator Cuff Impingement Syndrome|Impingement Syndrome|Adhesive Capsulitis|Rotator Cuff Injuries
Interventions: DRUG: Suprascapular nerve block with bipuvacaine|PROCEDURE: Pulsed radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RWE-based Treatment Patterns and Outcomes in CIDP
Status: NOT_YET_RECRUITING
Conditions: Chronic Inflammatory Demyelinating Polyneuropathy|Guillain-Barre Syndrome|Hereditary Amyloidosis
Interventions: OTHER: No intervention. Retrospective observation only.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ketogenic Diet Compliance in Patients Affected by Locally Advanced Rectal Cancer Patients Who Undergo to Radiotherapy
Status: NOT_YET_RECRUITING
Conditions: Rectal Cancer
Interventions: OTHER: Ketogenic Diet|OTHER: Standard Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I/II Study Of Immunization With Lymphotactin And Interleukin 2 Gene Modified Neuroblastoma Tumor Cells
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: SNJB-JF-IL2 and SJNB-JF-Lptn + Dose Level 1 SKNLP|BIOLOGICAL: SNJB-JF-IL2 and SJNB-JF-Lptn + Dose Level 2 SKNLP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Effects of Bariatric Arterial Embolization vs Bariatric Surgery
Status: RECRUITING
Conditions: Obesity|Type2diabetes|Bariatric Surgery Candidate|Metabolic Disease
Interventions: OTHER: Roux-en-Y gastric By-pass (RYGB) surgery|OTHER: Bariatric Arterial Embolization (BAE) procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL
Status: RECRUITING
Conditions: Leukemia, Myeloid, Chronic|Myeloid Leukemia|Chronic Myeloid Leukemia|Philadelphia Positive Acute Lymphoblastic Leukemia|B Cell Precursor Type Acute Leukemia
Interventions: DRUG: Ascentage Pharma HQP1351 bioavailable inhibitor|DRUG: Blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetic Peripheral Neuropathic Pain (DPNP)
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: DRUG: BMS-954561|DRUG: Pregabalin|DRUG: Placebo matching BMS-954561|DRUG: Placebo matching Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Filgotinib|DRUG: PTM filgotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Status: RECRUITING
Conditions: Pulmonary Hypertension|Interstitial Lung Disease
Interventions: DRUG: Treprostinil Palmitil Inhalation Powder|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk of Rupture of Aneurysms of the Thoracic Ascending Aorta (ATA) From the Dynamic Imaging
Status: TERMINATED
Conditions: Aortic Aneurysm, Thoracic
Interventions: DEVICE: dynamic imaging|DEVICE: mechanical testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Home-based Compression Therapy for Arm and Truncal Lymphedema in Breast Cancer
Status: COMPLETED
Conditions: Arm Lymphedema|Truncal Lymphedema|Breast Cancer
Interventions: DEVICE: Flexitouch System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Colony-stimulating Factors in Treating Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: epoetin alfa|BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: epirubicin hydrochloride|DRUG: fluorouracil|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Requirement for Vitamin D in Adolescents Aged 14-18 Years
Status: COMPLETED
Conditions: Serum 25-hydroxyvitamin D Concentrations (25OHD)
Interventions: DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis Patients
Status: TERMINATED
Conditions: Digital Ulcers
Interventions: DRUG: Macitentan 3 mg|DRUG: Macitentan 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Pulsed Radiofrequency for Sciatica and Disc Herniation
Status: COMPLETED
Conditions: Sciatica|Lumbar Disc Herniation
Interventions: PROCEDURE: pulsed Radiofrequency|PROCEDURE: Transforaminal Epidural Steroid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Lazertinib Therapy in EGFR-Mutation Positive Lung Adenocarcinoma Detected by BALF Liquid Biopsy
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Neoadjuvant lazertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aerosols in the Treatment of Pneumocystis Pneumonia: A Pilot Study Quantitating the Deposition of Aerosolized Pentamidine as Delivered in ACTG 040 and Comparing Its Toxicity With Parenteral Pentamidine Therapy
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Pentamidine isethionate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Observe the Effectiveness and Safety of IBI310, Bevacizumab Combined With Sintilimab in the Treatment of Advanced Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: IBI310（0.5mg/kg）|DRUG: IBI310（0.3mg/kg）|DRUG: sintilimab|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing the Safety and Efficacy of 0.5% Ivermectin Cream to Placebo in Lice Infested Subjects
Status: COMPLETED
Conditions: Head Lice
Interventions: DRUG: Ivermectin cream|DRUG: vehicle control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sarcopenia on Hepatocellular Carcinoma(HCC) After Systemic Therapies
Status: ENROLLING_BY_INVITATION
Conditions: Hepatocellular Carcinoma|Sarcopenia
Interventions: DIAGNOSTIC_TEST: Diagnostic Test: gait speed; ct scan; grip strength and chair stand test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TMC278-TiDP6-C136: Effect of TMC278 on Ethinylestradiol and Norethindrone in Healthy Women.
Status: COMPLETED
Conditions: HIV|AIDS|Oral Contraceptive
Interventions: DRUG: TMC278
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study on the Use of Hydrocortisone, Vitamin c and Tiamine in Patient With Sepsis and Septic Shock
Status: COMPLETED
Conditions: Sepsis|Septic Shock
Interventions: DRUG: red blood cells transfusion, tranexamic acid (TXA) and fibrinogen concentrate|DRUG: on crystalloid fluid and Tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Pulsed Electromagnetic Field Therapy for Management of Post-operative Pain Following Cesarean Delivery
Status: TERMINATED
Conditions: Pain
Interventions: DEVICE: Pulsed electromagnetic field device (ActiPatch TM)|DEVICE: Inactive pulsed electromagnetic field device (ActiPatch TM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Haploidentical Hematopoietic Stem Cell Transplantation for Acute Leukemias
Status: UNKNOWN
Conditions: Leukemia, Myeloid, Acute|Precursor Cell Lymphoblastic Leukemia-Lymphoma
Interventions: PROCEDURE: Haploidentical Stem Cell Transplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Sunlight Activated Synthetic Porphyrin in COVID-19 Infected Patients
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: SnPP Protoporphyrin plus Sunlight exposure|DRUG: SnPP Protoporphyrin plus Sunlight exposure|DRUG: SnPP Protoporphyrin plus Sunlight exposure|DRUG: Sulfonatoporphyrin(TPPS) plus Sunlight exposure.|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Catheter Pressure Ulcer Prevention in Pediatry : Use of Compresses Versus Standard Care
Status: COMPLETED
Conditions: Pressure Ulcer
Interventions: OTHER: peripheral venous catheter with compress under the catheter-extension tube junction|OTHER: peripheral venous catheter without compress under the catheter-extension tube junction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Local Anesthetic Infiltration to Prevent Postoperative Pain After Lumbar Surgery
Status: COMPLETED
Conditions: Hyperalgesia
Interventions: DRUG: Ropivacaine / Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Levels of Fear and Anxiety and Monitoring Wound Healing Among Patients Who Are About to Undergo Wisdom Tooth Extraction Surgery or Jaw Implant Surgery Under Local Anesthesia Versus General Anesthesia
Status: RECRUITING
Conditions: Tooth Extraction
Interventions: PROCEDURE: Reginal anesthesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Two Pulmonary Vein Ablation Techniques for Persistent AF
Status: UNKNOWN
Conditions: Chronic Atrial Fibrillation|Persistent Atrial Fibrillation
Interventions: PROCEDURE: RF ablation PVI alone|PROCEDURE: RF ablation PVI plus LPAW
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use and Reproducibility of Duplex Ultrasound to Provide Indices of Left Common Iliac Vein Diameter
Status: COMPLETED
Conditions: May-Thurner Syndrome
Interventions: DIAGNOSTIC_TEST: Duplex ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Vitamin D on Cognitive Decline of Patients With Memory Complaint
Status: COMPLETED
Conditions: Memory Disorders|Age-Related Cognitive Decline
Interventions: DRUG: Cholecalciferol 100 000 UI|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dry Eye Treatments on the Ocular Surface
Status: COMPLETED
Conditions: Keratoconjunctivitis Sicca|Dry Eye Syndrome
Interventions: DRUG: Dexamethasone|DRUG: Artificial tear
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Treatment After Total Knee Replacement - Continuous Epidural Versus Intravenous Patient Controlled Analgesia With Morphine
Status: TERMINATED
Conditions: Pain, Postoperative|Osteoarthritis
Interventions: DRUG: Marcaine 0.166% + Fentanyl 3.33 mcg/ml|DRUG: Morphine sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Transplantation of Autologous CD34+ Cells Transduced With the G2ARTE Lentiviral Vector Expressing the DCLRE1C cDNA in Artemis (DCLRE1C) Deficient Severe Combined Immunodeficiency Patients (ARTEGENE)
Status: RECRUITING
Conditions: Artemis (DCLRE1C ) Deficient Severe Combined Immunodeficiency
Interventions: GENETIC: ARTEGENE drug product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-Time-in-Human (FTIH) Study to Evaluate the Safety, Tolerability and Pharmacokinetics (PK) of VH4004280 in Healthy Participants
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: VH4004280|DRUG: Placebo|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TDI01 Suspension in the Treatment of Chronic Graft-versus-host Disease (cGVHD))
Status: RECRUITING
Conditions: GVHD, Chronic
Interventions: DRUG: TDI01 suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the PK of Single and Optional Multiple Dosing Regimens of MR Formulations of PCS499 Compared to Trental® Administered to Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PCS499|DRUG: Trental
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dyslipidemia in Cardiovascular Disease
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: Atorvastatin (Lipilou)|DRUG: Atorvastatin (Lipitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Walking Intervention With Additional Weights on the Unaffected Leg in People After Stroke
Status: COMPLETED
Conditions: Stroke|Hemiparesis
Interventions: BEHAVIORAL: Weighted brace|BEHAVIORAL: Non weighted brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Technological Rehabilitation of Distal Sensorimotor Polyneuropathy in Diabetic Patients
Status: COMPLETED
Conditions: Complications of Diabetes Mellitus|Diabetic Neuropathies
Interventions: DEVICE: Technological Rehabilitation|OTHER: Control Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioenergetics of Exercise-Induced Menstrual Disturbances
Status: COMPLETED
Conditions: Menstruation Disturbances|Luteal Phase Defect|Amenorrhea|Oligomenorrhea
Interventions: OTHER: Sedentary Control|OTHER: Exercising control|OTHER: 15 percent energy deficit|OTHER: 30 percent energy deficit|OTHER: 30 percent energy deficit (15/15)|OTHER: 60 percent energy deficit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intraperitoneal tgDCC-E1 and Intravenous Paclitaxel in Women With Platinum-Resistant Ovarian Cancer
Status: TERMINATED
Conditions: Ovarian Cancer
Interventions: BIOLOGICAL: Intraperitoneal tgDCC-E1A|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melatonin Premedication in Children Undergoing Surgery
Status: COMPLETED
Conditions: Premedication|Anaesthesia
Interventions: DRUG: melatonin in children premedication|DRUG: midazolam in children premedication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hear Again, Work Again
Status: RECRUITING
Conditions: Hearing Loss, Sensorineural, Severe|Hearing Loss, Sensorineural, Bilateral|Hearing Loss, Unilateral|Hearing Loss, Sensorineural, Profound|Cochlear Implants
Interventions: OTHER: Cochlear implant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunogenicity and Safety of BoostrixTM Using a New Syringe in 10 to 15-year Old Adolescents
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Acellular Pertussis
Interventions: BIOLOGICAL: Boostrix TM (new syringe presentation)|BIOLOGICAL: Boostrix TM (previous syringe presentation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: EpiConCES - Epidural Lidocaine for Conversion to CaEsarean Section
Status: UNKNOWN
Conditions: Pregnant Women>37SA
Interventions: DRUG: Lidocaine 2% adrénalinée|DEVICE: Epidural catheter|PROCEDURE: Caesarean section
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of JMT103 in Patients With Bone Metastases From Solid Tumors
Status: COMPLETED
Conditions: Bone Metastases From Solid Tumors
Interventions: DRUG: Drug: JMT103- 120 mg SC Q4W|DRUG: Drug: JMT103- 120 mg SC Q8W|DRUG: Drug: JMT103- 180 mg SC Q8W|DIETARY_SUPPLEMENT: Dietary Supplement: Calcium Dietary Supplement: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mistletoe as Complementary Treatment in Patients With Advanced Non-small-cell Lung Cancer (NSCLC), Treated With Carboplatin/Gemcitabine Chemotherapy Combination.
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Mistletoe extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Vamorolone in Boys Ages 2 to <4 Years and 7 to <18 Years With Duchenne Muscular Dystrophy (DMD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Vamorolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Statin Effects on Beta-Amyloid and Cerebral Perfusion in Adults at Risk for Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 2 Etirinotecan Pegol in Refractory Brain Metastases & Advanced Lung Cancer / Metastatic Breast Cancer
Status: COMPLETED
Conditions: Stage IV Non-small Cell Lung Cancer (NSCLC)|Recurrent Non-small Cell Lung Cancer (NSCLC)|Extensive-stage Small Cell Lung Cancer (SCLC)|Recurrent Small Cell Lung Cancer (SCLC)|Tumors Metastatic to Brain|Metastatic Breast Cancer (mBC)
Interventions: DRUG: Pegylated Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Once Versus Twice Daily Mesalamine to Induce Remission in Pediatric Ulcerative Colitis
Status: COMPLETED
Conditions: Mild to Moderate Ulcerative Colitis
Interventions: DRUG: Mesalamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PTSD Screening in Pregnant Black Women
Status: NOT_YET_RECRUITING
Conditions: Pregnancy Early|PTSD
Interventions: BEHAVIORAL: Culturally Responsive SBIRT for OB|BEHAVIORAL: Brief Screening for PTSD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Performance of 13C Mannitol for in Vivo Measurement of Small Intestinal Permeability
Status: COMPLETED
Conditions: Impaired Small Intestinal Permeability
Interventions: DIETARY_SUPPLEMENT: 12C mannitol|DRUG: Indomethacin|DIETARY_SUPPLEMENT: 13C mannitol|DIETARY_SUPPLEMENT: Lactulose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Double-Blind, Placebo-Controlled Safety and Efficacy Study of NA-831
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Alzheimer Disease|Alzheimer Dementia|Dementia, Vascular|Dementia With Lewy Bodies|Cognitive Impairment|Tauopathies|Neurodegenerative Diseases|Neurocognitive Disorders|Cognitive Disorder
Interventions: DRUG: N-831(Traneurocin) 10 mg QD|DRUG: NA-831 (Traneurocin) 20 mg QD|DRUG: NA-831 (Traneurocin) 40 mg QD|DRUG: Placebo oral capsule QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Normobaric Hyperoxia Combined With Endovascular Treatment for Acute Ischemic Stroke
Status: COMPLETED
Conditions: Stroke|Endovascular Treatment|Neuroprotection
Interventions: OTHER: Normobaric oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hearts in Rhythm Organization (HiRO)National Registry and Bio Bank
Status: ENROLLING_BY_INVITATION
Conditions: Sudden Cardiac Arrest|Sudden Arrhythmic Death Syndrome|Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)|Long QT Syndrome (LQTS)|Hypertrophic Cardiomyopathy (HCM)|Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PDA Occlusion Using NIRS
Status: RECRUITING
Conditions: Organ Perfusion Determined by Using NIRS Post Transcatheter PDA Occlusion or Medical Closure of PDA
Interventions: DEVICE: NIRS monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exogenous Ketosis in a Fed and a Fasted State
Status: RECRUITING
Conditions: Ketosis|Exogenous Ketosis
Interventions: DIETARY_SUPPLEMENT: Ketone Monoester|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety Study of RMJH-111b to Treat Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Magnesium citrate, tribasic anhydrous soft gelatin capsule|DRUG: Placebo soft gelatin capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Isonicotinic Acid Hydrazide Prior to Diagnostic Office Hysteroscopy in Primarily Infertile Patients
Status: COMPLETED
Conditions: Infertility, Female
Interventions: DRUG: INH|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Musculoskeletal Pain in Long-term Dizziness
Status: COMPLETED
Conditions: Vestibular Disease|Musculoskeletal Pain|Rehabilitation
Interventions: BEHAVIORAL: Vestibular exercises combined with body awareness exercises and cognitive therapy|BEHAVIORAL: Exergaming
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trans-spinal Electrical Stimulation in Individuals With Spinocerebellar Ataxia
Status: ENROLLING_BY_INVITATION
Conditions: SCA|Postural Balance|Gait Ataxia
Interventions: DEVICE: TRANSCRANIAL DIRECT CURRENT STIMULATION + exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of WJ47156 Monotherarpy and in Combination With Other Therapy in Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Malignant Solid Tumors
Interventions: DRUG: WJ47156|DRUG: JS001+Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Deficiency in Patients With Hypertension
Status: TERMINATED
Conditions: Vitamin D Deficiency|Hypertension
Interventions: DRUG: Aliskiren|DIETARY_SUPPLEMENT: Cholecalciferol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT