pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: PRACT to Investigate Controlling Alcohol Related Harms in a Low-Income Setting; Emergency Department BIs in Tanzania
Status: RECRUITING
Conditions: Alcohol Use Disorder|Injury Traumatic|Trauma
Interventions: BEHAVIORAL: PPKAY (brief intervention)|BEHAVIORAL: Standard Booster|BEHAVIORAL: Personalized Booster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Drug-drug Interaction of HSK16149 Capsule With Probenecid Tablets or Cimetidine Tablets in Healthy Subjects
Status: COMPLETED
Conditions: PHN - Post-Herpetic Neuritis
Interventions: DRUG: HSK16149，probenecid, cimetidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of LY3022855 in Combination With Durvalumab or Tremelimumab in Participants With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: LY3022855|DRUG: Durvalumab|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CARTO-Finder Guided Ablation Versus Multiscale Entropy Guided Ablation in Persistent Atrial Fibrillation
Status: NOT_YET_RECRUITING
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: Multiscale entropy-guided ablation plus PVI|PROCEDURE: CARTO-Finder-guided ablation plus PVI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stricture Definition and Treatment (STRIDENT) Endoscopic Therapy Study
Status: UNKNOWN
Conditions: Crohn Disease|Inflammatory Bowel Diseases|Stricture; Bowel
Interventions: PROCEDURE: Standard (single) endoscopic stricture dilatation|PROCEDURE: Intensive endoscopic stricture dilatation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Olive Oil and Bran Oil on Antioxidant Levels, Glycemic Control, and Lipid Profile in Patient Type 2 DM
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Oxidative Stress|Glucose, High Blood|Lipid Disorder
Interventions: BIOLOGICAL: olive oil|BIOLOGICAL: bran oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Endothelial Keratoplasty Outcomes
Status: COMPLETED
Conditions: Fuchs' Endothelial Corneal Dystrophy|Bullous Keratopathy|Iridocorneal Endothelial Syndrome|Posterior Polymorphous Dystrophy
Interventions: PROCEDURE: endothelial keratoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psilocybin in Alcohol Use Disorder With Comorbid Depression
Status: NOT_YET_RECRUITING
Conditions: Alcohol-Related Disorders|Depressive Disorder|Addiction
Interventions: DRUG: Psilocybin therapy|DRUG: Inactive Psilocybin therapy|OTHER: Electroencephalogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Left Bundle Branch Area Pacing As A Rescue Strategy for Cardiac Resynchronization Therapy Non-Response
Status: RECRUITING
Conditions: Systolic Heart Failure|Heart Failure With Reduced Ejection Fraction|CRT Non-Response|Left Bundle Branch Area Pacing
Interventions: DEVICE: Left bundle branch area pacing|DIAGNOSTIC_TEST: Cardiac MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proteomic Signature in Breast Cancer: Correlation With Tumor Response to Neo-adjuvant Chemotherapy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: Blood sampling|PROCEDURE: BIOPSY|PROCEDURE: SURGERY
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Closed Kinetic Chain Exercise Versus Russian Current Stimulation in Rehabilitation of Colles' Fracture.
Status: COMPLETED
Conditions: Distal Radius Fracture
Interventions: OTHER: traditional exercise|OTHER: Russian current stimulation|OTHER: closed kinetic chain exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Internet Delivered Cognitive Behavioural Therapy for Persons With Mild Traumatic Brain Injury
Status: COMPLETED
Conditions: Mild Traumatic Brain Injury|Internet-Delivered Cognitive Behavioural Therapy|Depression|Anxiety
Interventions: BEHAVIORAL: Internet-delivered Cognitive Behavioural Therapy(ICBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decompression Versus Instrumented Fusion for Lumbar Degenerative Disease. Clinical and Biomechanical Outcome Study
Status: RECRUITING
Conditions: Lumbar Spinal Stenosis|Degenerative Lumbar Spinal Stenosis
Interventions: PROCEDURE: microsurgical decompression|PROCEDURE: decompression and instrumented fusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Amantadine for Risperidone Consta or Paliperidone Treated Patients to Decrease Prolactin Elevation
Status: TERMINATED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Amantadine Hydrochloride, USP|DRUG: Amantadine Hydrochloride, USP|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quadratus Lumborum Block vs Transversus Abdominis Plane Block in Bladder Cancer Surgeries
Status: UNKNOWN
Conditions: Quadratus Lumborum Block|Transversus Abdominis Plane Block|Bladder Cancer|Postoperative Pain|Surgery
Interventions: PROCEDURE: Quadratus lumborum block|PROCEDURE: Transversus abdominis plane block|DRUG: Intravenous opioid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 3 Study to Evaluate Safety and Efficacy of Iclaprim Versus Vancomycin for ABSSSI: REVIVE-1
Status: COMPLETED
Conditions: Skin Structures and Soft Tissue Infections
Interventions: DRUG: iclaprim|DRUG: vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Facial Measurements, the Length of Mouth Corner-mandible Angle and Incisors-mandible Angle, for Determining the Proper Sizes of Oropharyngeal Airway
Status: COMPLETED
Conditions: General Anesthesia
Interventions: DEVICE: the length between incisor and mandible angle|DEVICE: the length between mouth corner-mandible angle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety of Resatorvid in Adults With Severe Sepsis
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: Resatorvid|DRUG: Resatorvid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of a Self-collection Device for Cervical Cancer Screening
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Papilloma Virus Infection Type 16|Human Papilloma Virus Infection Type 18|Human Papilloma Virus
Interventions: DEVICE: Teal Health Self-Collection Device Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Intravesical LGG VS Saline Bladder Wash RCT
Status: RECRUITING
Conditions: Spinal Cord Injuries|Neurogenic Bladder
Interventions: DRUG: Lactobacillus RhamnosusGG|DRUG: Saline bladder wash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Evaluation of Safety and Effectiveness of Intraarticular Administration of Autologous Stromal-Vascular Fraction of Adipose Tissue Cells for Treatment of Knee Joint Arthrosis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Stromal-vascular fraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temozolomide in Preventing Brain Metastases in Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Small Cell Lung Cancer|Metastatic Carcinoma
Interventions: DRUG: temozolomide|RADIATION: prophylaxis cranial radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OHI--Randomized Control Trial to Evaluate Efficacy, Acceptability, and Perception of Benefit of an Innovative Custom AFO
Status: COMPLETED
Conditions: Accidental Falls|Fall Due to Loss of Equilibrium|High Risk of Falls Due to Mobility Limitation|Diabetes|Arthritis|Cancer|Peripheral Arterial Disease|Parkinson's Disease|End Stage Renal Failure on Dialysis
Interventions: DEVICE: MBB AFO|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Wound Treatment With 3% Sodium Pentaborate Pentahydrate
Status: UNKNOWN
Conditions: Wound Healing
Interventions: DRUG: 3% Sodium Pentaborate Pentahydrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Helicobacter Pylori Eradication in Diabetic Subjects With Non-alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DRUG: H.pylori eradication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Afatinib Plus Toripalimab in Previously Treated ESCC With EGFR Overexpression or EGFR Amplification
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Afatinib|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Deconditioning and Reconditioning in Colon Cancer Patients: an APA Muscle Rendorcement Program
Status: NOT_YET_RECRUITING
Conditions: Colon Cancer|Muscle Strengthening
Interventions: PROCEDURE: Muscle biopsies|OTHER: Muscle Strengthening|BIOLOGICAL: Blood and urine samples|OTHER: Aerobic Training|OTHER: Evaluation 1 pre-surgery|OTHER: Evaluation 2 post-surgery|OTHER: Intermediate Evaluation 3|OTHER: Final post-training evaluation 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Food Effect on the Pharmacokinetics of Ensartinib Capsules in Chinese Healthy Volunteers.
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Ensartinib with fed or fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Meaning of Dopaminergic Pathway in Sleep Breathing Disorders.
Status: ENROLLING_BY_INVITATION
Conditions: Sleep Apnea|Sleep-Disordered Breathing
Interventions: DIAGNOSTIC_TEST: Polysomnography|DIAGNOSTIC_TEST: Blood dopamine level measurement|DIAGNOSTIC_TEST: Genetical test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Variable Lidocaine Concentrations in Tumescent Anesthesia for Pain Control During and After Endovenous Laser Procedure; Non-inferiority Trial
Status: UNKNOWN
Conditions: Pain During and After Endovenous Laser Obliteration of Large Saphenous Vein Based on Lidocaine Tumescent Concentration
Interventions: DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Efficacy and Safety of Froniglutide (PF1801) in Patients With Idiopathic Inflammatory Myopathy
Status: RECRUITING
Conditions: Dermatomyositis|Polymyositis|Idiopathic Inflammatory Myopathies
Interventions: DRUG: Froniglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of Circularity and Diameter of Femtosecond Laser Versus Manual Anterior Capsulotomy in Singapore National Eye Centre
Status: COMPLETED
Conditions: Primary Disease: Cataract
Interventions: DEVICE: Femtosecond Laser (VICTUS™ Femtosecond Laser Platform)|DEVICE: Manual (CCC technique with Utrata forceps)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Valsartan on Left Ventricular Myocardial Functions in Hypertensive Patients With Left Ventricular Hypertrophy
Status: COMPLETED
Conditions: Hypertension|Left Ventricular Hypertrophy
Interventions: DRUG: valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antineoplaston Therapy in Treating Patients With Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Ultrasonographic Comparison of the Effect of Hot and Cold Therapy on Spasticity
Status: UNKNOWN
Conditions: Spastic Hemiplegia
Interventions: OTHER: Heat Therapy with heating pads|OTHER: Cold Therapy with ice packs|OTHER: Stretching Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of a Metabolic Nutritional Therapy for the Management of Primary Brain Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma
Interventions: OTHER: Energy restricted Ketogenic Diet (ERKD) (Metabolic Nutritional Therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of 3 Investigational Products on the Microbiome and Scalp Attributes in Children With Curly Hair
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Investigational Shampoo|OTHER: Investigational Conditioner|OTHER: Investigational Combing Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Consequences of a Maternal-fetal Chikungunya Virus Infection
Status: COMPLETED
Conditions: Chikungunya Virus Infection
Interventions: OTHER: OPHTHALMOLOGICAL ASSESSMENT|OTHER: NEUROPSYCHOLOGICAL ASSESSMENT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Combination Chemotherapy in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: dexamethasone|DRUG: doxorubicin hydrochloride|DRUG: methotrexate|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Berzosertib Human Mass Balance Study (DDRiver Solid Tumors 208)
Status: COMPLETED
Conditions: Advanced Solid Tumor
Interventions: DRUG: [14C]M6620|DRUG: M6620|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Plaque Disclosing Toothpaste on Home Oral Hygiene Procedures
Status: UNKNOWN
Conditions: Chronic Gingivitis, Plaque Induced
Interventions: OTHER: Shoplaq toothpaste|OTHER: Colgate toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cervical Ripening Balloon for 12 Hours vs. 1 Hour.
Status: NOT_YET_RECRUITING
Conditions: Induction of Labor
Interventions: DEVICE: cervical ripening balloon for one hour|DEVICE: cervical ripening balloon for twelve hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Bortezomib and Carboplatin in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Clear Cell Adenocarcinoma|Fallopian Tube Endometrioid Adenocarcinoma|Fallopian Tube Mucinous Adenocarcinoma|Fallopian Tube Serous Adenocarcinoma|Fallopian Tube Transitional Cell Carcinoma|Ovarian Brenner Tumor|Ovarian Clear Cell Adenocarcinoma|Ovarian Clear Cell Cystadenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mucinous Adenocarcinoma|Ovarian Mucinous Cystadenocarcinoma|Ovarian Seromucinous Carcinoma|Ovarian Serous Adenocarcinoma|Ovarian Serous Cystadenocarcinoma|Ovarian Transitional Cell Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Undifferentiated Fallopian Tube Carcinoma|Undifferentiated Ovarian Carcinoma
Interventions: DRUG: Bortezomib|DRUG: Carboplatin|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Unilateral Robotic Assistance on Compensation Strategies and Muscular Activity During Hemiparetic Gait
Status: COMPLETED
Conditions: Hemiparesis/Hemiplegia (One Sided Weakness/Paralysis)
Interventions: DEVICE: Exoskeleton assisted gait on a treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intraligmentary Dexamethasone in Lower First Molars With Irreversible Pulpitis and Apical Periodontits
Status: NOT_YET_RECRUITING
Conditions: Pulpitis - Irreversible
Interventions: PROCEDURE: Inferior alveolar nerve block with dexamethasone|PROCEDURE: Buccal infiltratation with dexamethasone|PROCEDURE: Inferior alveolar nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Korean Medicine for Lumbar Stenosis Patients With Sciatica
Status: TERMINATED
Conditions: Lumbar Spinal Stenosis
Interventions: DRUG: Herbal medicine|PROCEDURE: Chuna manipulation|PROCEDURE: Bee venom pharmacopuncture|PROCEDURE: Pharmacopuncture|PROCEDURE: Acupuncture|PROCEDURE: Electroacupuncture|PROCEDURE: Cupping|OTHER: Other intervention(s)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase IV Study of Huazhi Rougan Granule
Status: COMPLETED
Conditions: A Phase IV Trial to Investigate the Efficacy and Safety of Huazhi Rougan Granule in the Treatment of Non-alcoholic Simple Fatty Liver
Interventions: DRUG: Huazhi Rougan Granule Placebo granule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Evaluation of a Glass Ionomer Cement (GIC) Based Restorative System Versus Bulk Filled Resin-based Composite
Status: UNKNOWN
Conditions: Caries
Interventions: OTHER: composite restoration|OTHER: glass ionomer cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effect of Metformin vs. Pep2dia as an Adjunct to Letrozole on Ovulation Induction and Pregnancy Outcomes in Overweight Women With PCOS
Status: RECRUITING
Conditions: PCOS
Interventions: DRUG: Metformin|DRUG: pep2dia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Diagnosis of Tuberculosis in HIV Infected Children in Asia (Cambodia, Vietnam)and Africa (Burkina Faso, Cameroon)
Status: COMPLETED
Conditions: HIV|Tuberculosis|Pediatrics
Interventions: OTHER: Development of a diagnosis algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: NUC in Preventing HBV Reactivation in HCV/HBV Co-infected Patients Receiving DAA for CHC
Status: UNKNOWN
Conditions: HBV/HCV Co-infection
Interventions: DRUG: 24-week Entecavir|DRUG: 12-week Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of 5-Fluorouracil and Leucovorin and Intra-abdominal Floxuridine Chemoradiation in Patients With Fully Resected Locally Advanced Gastric Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Adenocarcinoma|Gastric Cancer
Interventions: DRUG: floxuridine, 5-Fluorouracil, leucovorin|PROCEDURE: External Beam Radiotherapy|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Attachment and Biobehavioral Catch-up and Depression Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Maternal Depression|Child Behavior Problem
Interventions: BEHAVIORAL: Attachment and Biobehavioral Catch up|BEHAVIORAL: Attachment and Biobehavioral Catch up Plus Depression Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Polyphenon E in Men With High-grade Prostatic Intraepithelial Neoplasia
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: DRUG: Polyphenon E|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Integrated Approach to Treating Recurrent Thoracic Carcinomas Resistant to Tyrosine Kinase Inhibitors
Status: COMPLETED
Conditions: Adenocarcinoma of Lung|Lung Neoplasm|Cancer of Lung|Lung Cancer|Pulmonary Cancer|EGFR Genes|ALK Genes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of DF289 Plus DF277 Otic Solution in the Treatment of Middle Ear Infections in Pediatric Patients
Status: COMPLETED
Conditions: Acute Otitis Media
Interventions: DRUG: DF289|DRUG: DF277|DRUG: DF289 plus DF277
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FOLFIRI + Bevacizumab With or Without Dalteparin in First Line Treatment of Advanced Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: Fragmin, 5-Fluorouracil, Folinic Acid, irinotecan, bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining the Use of Three Dimensional Ultrasound in the Assessment of Vascular Pathologies
Status: NOT_YET_RECRUITING
Conditions: PAD - Peripheral Arterial Disease|Vascular Diseases|Wounds
Interventions: DEVICE: PIUR tUS Imaging System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Giving Combinations of Three or Four Anti-HIV Drugs to HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nelfinavir mesylate|DRUG: Delavirdine mesylate|DRUG: Stavudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: mHealth Mindfulness With Patients With Serious Illness and Their Caregivers
Status: RECRUITING
Conditions: Caregiver Stress Syndrome|Anxiety
Interventions: BEHAVIORAL: Mindfulness Coach|BEHAVIORAL: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety/Efficacy Study Comparing the Misoprostol Vaginal Insert to Cervidil for Cervical Ripening and Induction of Labor
Status: COMPLETED
Conditions: Cervical Ripening|Labor, Induced
Interventions: DRUG: Misoprostol vaginal insert 100 mcg|DRUG: Misoprostol vaginal insert 50 mcg|DRUG: Dinoprostone vaginal insert (Cervidil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of a Repetitive Transcranial Magnetic Stimulation (rTMS) Device for the Treatment of Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Onreltea (Brimonidine) Gel In Pediatric Patients With Capillary Malformations
Status: TERMINATED
Conditions: Capillary Malformations
Interventions: DRUG: Brimonidine 0.33% gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of CG5503 Prolonged Release (PR) in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Pain|Knee Osteoarthritis
Interventions: DRUG: Tapentadol ER (100 to 250 mg twice daily)|DRUG: Matching Placebo (twice daily)|DRUG: Oxycodone CR (20 to 50 mg twice daily)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Esophagectomy: Sweet Versus Ivor-Lewis (ESVIL) (ECTOP-2001)
Status: COMPLETED
Conditions: Esophageal Neoplasms
Interventions: PROCEDURE: Esophagectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CUstodiol Versus RInger: whaT Is the Best Agent?
Status: COMPLETED
Conditions: Thoracoabdominal Aortic Aneurysms
Interventions: DRUG: Custodiol|DRUG: Enriched Ringer's lactate solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Safety and Efficacy of a Novel Furosemide Regimen
Status: WITHDRAWN
Conditions: Acute Decompensated Heart Failure
Interventions: DRUG: Furosemide Injection Solution 8mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patients With Newly Diagnosed Multiple Myeloma Comparing KTd vs. KRd Induction Therapy and Investigating a K-mono Maintenance Strategy
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Thalidomide|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Prophylactic Re-sorbable Biosynthetic Mesh Following Midline Laparotomy in Clean/Contaminated Field.
Status: RECRUITING
Conditions: Incisional Hernia After Midline Laparotomy
Interventions: PROCEDURE: Sub-lay mesh supported closure|DEVICE: BIO-A (GORE) mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Smartphone Intervention for Smoking Cessation and Improving Adherence to Treatment Among HIV Patients
Status: COMPLETED
Conditions: Smoking|Smoking Cessation|HIV
Interventions: DRUG: Nicoderm C-Q Transdermal Product|BEHAVIORAL: Adherence to Antiretroviral Therapy Counseling|BEHAVIORAL: Behavioral Smoking Cessation Counseling|BEHAVIORAL: "Crave-to-Quit" app|BEHAVIORAL: vDOT "emocha" app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Pethidine Plus Dexamethasone for Distal Lower Orthopedic Surgeries
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Bupivacaine Hydrochloride|DRUG: Pethidine plus Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Compliance Between Clonidine Patch and Methyldopa for the Treatment of Chronic Hypertension in Pregnancy
Status: WITHDRAWN
Conditions: Hypertension
Interventions: DRUG: methyldopa vs. clonidine|DRUG: clonidine patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study Evaluating the Co-Administration of Bremelanotide With Tirzepatide for the Treatment of Obesity
Status: RECRUITING
Conditions: Obesity
Interventions: DRUG: Bremelanotide|DRUG: Tirzepatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PENG Block Plus Lateral Femoral Cutaneous Nerve Block for Posterolateral-approached Total Hip Arthroplasty
Status: COMPLETED
Conditions: Pain|Postoperative Pain|Acute Pain|Analgesia|Hip Arthropathy|Postoperative Complications
Interventions: PROCEDURE: PENG Block|PROCEDURE: Lateral Femoral Cutaneous Nerve Block|PROCEDURE: Wound Infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-PD-1 Alone or Combined With Autologous DC-CIK Cell Therapy in Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: BIOLOGICAL: Anti-PD-1 plus DC-CIK|BIOLOGICAL: Anti-PD-1 alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ghrelin Plus Strength Training in Frail Elderly Study
Status: COMPLETED
Conditions: Frailty Syndrome
Interventions: DRUG: Ghrelin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Plasma Triglyceride Extraction by The Muscle
Status: COMPLETED
Conditions: Obesity|Insulin Resistance
Interventions: DRUG: Insulin|DRUG: NG-monomethyl-L-arginine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome
Status: RECRUITING
Conditions: Lynch Syndrome
Interventions: BIOLOGICAL: Adenovirus 5 CEA/MUC1/Brachyury Vaccine Tri-Ad5|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Colonoscopy|DRUG: Nogapendekin Alfa|DRUG: Placebo Administration|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Omega 3 Fatty Acids on Vascular Function
Status: COMPLETED
Conditions: Previous Myocardial Infarction
Interventions: DIETARY_SUPPLEMENT: Omega 3 fatty acid supplementation|DIETARY_SUPPLEMENT: Olive Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study To Evaluate The Effect Of GW876008 On The Pharmacokinetics Of Oral Contraceptive Pills
Status: TERMINATED
Conditions: Social Phobia
Interventions: DRUG: GW876008|DRUG: COC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial to Learn How Well REGN9933 and REGN7508 Work for Preventing Blood Clots, and How Safe They Are, in Adults Who Have a Peripherally Inserted Central Catheter (PICC)
Status: NOT_YET_RECRUITING
Conditions: Venous Thromboembolism
Interventions: DRUG: REGN9933|DRUG: REGN7508|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Azacitidine in Adult Taiwanese Subjects With Higher-Risk Myelodysplastic Syndromes (MDS)
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Outcomes in Dysvascular Transfemoral Amputees
Status: COMPLETED
Conditions: Transfemoral Amputation|Unilateral Traumatic Amputation of Leg at or Above Knee
Interventions: DEVICE: C leg compared to subject's mechanical leg (Otto Bock)|DEVICE: C leg compared to subject's mechanical leg (Otto Bock)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SGLT-2 Inhibitor Effects on Cardiac and Hepatic Metabolic Profiles for the Diabetes Patients Combined With Obesity
Status: COMPLETED
Conditions: Fatty Liver Disease
Interventions: DRUG: Canagliflozin 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Local Infiltration Anesthesia With Ropivacaine on Postoperative Pain After Hip Hemiarthroplasty
Status: COMPLETED
Conditions: Femoral Neck Fractures
Interventions: DRUG: Ropivacaine|DRUG: Epinephrine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Delivra Joint Health Cream In The Treatment Of Pain Caused By Osteoarthritis Of The Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: OTHER: Topical Arthritis Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of LY450139, on the Progression of Alzheimer's Disease as Compared With Placebo
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: LY450139|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Alone or With Radiation Therapy in Treating Children With Kidney Cancer
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: dactinomycin|BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: vincristine sulfate|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Relative Bioavailability, Effect of Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics (PK) of TAK-931 in Participants With Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms, Advanced Solid
Interventions: DRUG: TAK-931 PIC|DRUG: TAK-931 Tablet|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Assessing the Rates of Major Complications in Combined Mini-incision Microscopic Varicocelectomy
Status: COMPLETED
Conditions: Varicocele
Interventions: PROCEDURE: Combined Microscopic Varicocelectomy|PROCEDURE: Inguinal and Subinguinal varicocelectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Antiplatelet Effects Comparing Ticagrelor (Ticag. - AZD6140) With Clopidogrel (Clop.) Responder and Non-responders
Status: COMPLETED
Conditions: Stable Coronary Artery Disease
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ISB 1342, a CD38/CD3 Bispecific Antibody, in Subjects With Previously Treated Multiple Myeloma
Status: COMPLETED
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: BIOLOGICAL: ISB 1342
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Anal Basaloid Squamous Cell Carcinoma|Anal Canal Cloacogenic Carcinoma|Anal Margin Squamous Cell Carcinoma|Stage IIB Anal Cancer AJCC v8|Stage III Anal Cancer AJCC v8
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Colonoscopy|PROCEDURE: Computed Tomography|PROCEDURE: Digital Rectal Examination|PROCEDURE: High Resolution Anoscopy|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Nivolumab|OTHER: Patient Observation|PROCEDURE: Proctoscopy|PROCEDURE: Sigmoidoscopy|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Participants With Sarcoidosis-associated Pulmonary Hypertension (SAPH) to Assess the Efficacy and Safety of Oral Selexipag
Status: TERMINATED
Conditions: Sarcoidosis-associated Pulmonary Hypertension
Interventions: DRUG: Selexipag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Vitamin C on Skeletal Muscle
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Vitamin C|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Comparing Pharmacokinetic and Safety of QL2107 and Keytruda® (Marketed in China and the United States) in Healthy Adults
Status: RECRUITING
Conditions: Tumor
Interventions: DRUG: QL2107|DRUG: Keytruda®(china)|DRUG: Keytruda®(US)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Two Part Study to Evaluate Pharmacokinetics, Safety, and Antiviral Activity of Elvitegravir Administered With a PI/r Background Regimen for ARV Treatment-Experienced Pediatric Participants
Status: TERMINATED
Conditions: Acquired Immune Deficiency Syndrome (AIDS)|HIV Infections
Interventions: DRUG: EVG|DRUG: Background regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biological Collection From Samples From The Gut Microbiota In Patients Having A Bone Or Joint Infection Treated By A Suppressive Subcutaneous Antibiotherapy With Betalactamine (CARBAMICROBIOTA)
Status: RECRUITING
Conditions: Bone Infection|Joint Infection
Interventions: OTHER: Biological Collection From Samples From The Gut Microbiota
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Design and Evaluation of an Active Intervention for the Prevention of Non-contact ACL Injury
Status: COMPLETED
Conditions: Athletic Injuries|Sprains and Strains|Wounds and Injuries|Knee Injuries
Interventions: DEVICE: Activity Training with Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients With Preserved Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: LCZ696|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Ibrutinib in Patients With Symptomatic, Previously Untreated Waldenstrom's Macroglobulinemia, and Impact on Tumor Genomic Evolution Using Whole Genome Sequencing
Status: COMPLETED
Conditions: Waldenstrom's Macroglobulinemia
Interventions: DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Cetuximab With Afatinib for Patient With EGFR Mutated Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Afatinib|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Evaluation for the Treatment of HDM Induced Allergic Asthma and Rhinitis/Rhinoconjunctivitis
Status: NOT_YET_RECRUITING
Conditions: House Dust Mite Allergy|Perennial Allergic Rhinitis|Allergic Rhinoconjunctivitis|Allergic Asthma
Interventions: BIOLOGICAL: MM09 allergoid-mannan conjugates subcutaneous (3.000 UTm/mL)|BIOLOGICAL: MM09 allergoid-mannan conjugates Sublingual (3.000 UTm/mL)|BIOLOGICAL: MM09 allergoid-mannan conjugates Sublingual (9.000 UTm/mL)|BIOLOGICAL: Placebo subcutaneous|BIOLOGICAL: Placebo sublingual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label, Dose Titration Study of Sevelamer Carbonate Tablets & Powder in Hyperphosphatemic CKD Patients
Status: COMPLETED
Conditions: Renal Failure Chronic
Interventions: DRUG: sevelamer carbonate 800mg|DRUG: sevelamer carbonate 2.4 g
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of NETSPOT Imaging Versus F-FDG-PET in Head and Neck Cancer Patients
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: The isotope 68Ga, NETSPOT and 18F-FDG-PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Assess CT-868 and the Relationship Between Insulin Secretory Response and Ambient Blood Glucose.
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: CT-868 as SC Injection|DRUG: Placebo as SC Injection|DRUG: Active Comparator as SC Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dual Task Aerobic Exercise for Older Adults With Cognitive Impairment (HM2)
Status: COMPLETED
Conditions: Cognitive Impairment
Interventions: BEHAVIORAL: Exercise Intervention|BEHAVIORAL: Exercise Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Spectacle Tints and Thin-Films for Migraine
Status: TERMINATED
Conditions: Headache Migraine Chronic
Interventions: DEVICE: Gray tinted spectacle lenses|DEVICE: Thin-Film spectacle lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pseudoephedrine Prophylaxis for Prevention of Middle Ear Barotrauma in Hyperbaric Oxygen Therapy
Status: COMPLETED
Conditions: Barotrauma;Ear
Interventions: PROCEDURE: Hyperbaric Oxygen Therapy|DRUG: Pseudoephedrine 60 MG|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cabergoline as a Preventive Treatment for Chronic Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Cabergoline 0.5 MG|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluoroscopic &Ultrasonographic Guidance of Superior Hypogastric Plexus Neurolysis in Intractable Pelvic Pain
Status: COMPLETED
Conditions: Intractable Pelvic Cancer Pain
Interventions: PROCEDURE: fluroscopic guided block|PROCEDURE: double modality (ultrasound and fluroscopic) guided block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Multimodal Analgesia on Serum MCP-1, BDNF, and MiRNA-124 in Hysterectomy Surgery
Status: COMPLETED
Conditions: Inflammation|Inflammatory Response|Acute Pain|Chronic Pain
Interventions: DRUG: Multimodal analgesia|DRUG: Conventional intravenous analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Early Prescription of Radiography Using the Ottawa Ankle Rules by a Nurse in the Management of Isolated Ankle Trauma
Status: COMPLETED
Conditions: Ankle Injuries|Nurse's Role|Emergencies
Interventions: OTHER: OAR application by a nurse
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC