pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Vaccination in Prostate Cancer (VANCE)
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: ChAdOx1.5T4|BIOLOGICAL: MVA.5T4|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional and Electromyographical Changes After PRP or Dextrose Injection in Chronic Lateral Epicondylitis
Status: UNKNOWN
Conditions: Tennis Elbow
Interventions: DRUG: Platelet Rich Plasma|DRUG: Dextrose 50%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of DMF and the Effects of DMF on Exploratory Biomarkers
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: BG00012 (DMF) (Tecfidera®.)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xenin-25: Novel Regulator of Insulin Secretion and Beta-cell Function
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Placebo|DRUG: Glucose-dependent Insulinotropic Polypeptide (GIP)|DRUG: Xenin-25|DRUG: Glucose-dependent Insulinotropic Polypeptide plus Xenin-25
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Local Anesthesia Before Bulkamid Injection
Status: RECRUITING
Conditions: Stress Urinary Incontinence|Intrinsic Sphincter Deficiency
Interventions: PROCEDURE: Topical lidocaine|PROCEDURE: EMLA cream|PROCEDURE: Periurethral block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Open Chain Versus Closed Chain Segmental Control Exercises on CSA of Lumbar Multifidus Muscle in Chronic MLBP
Status: RECRUITING
Conditions: Mechanical Low Back Pain
Interventions: OTHER: Conventional treatment|OTHER: Open chain segmental control|OTHER: Closed chain segmental control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Using ctDNA to Determine Therapies for Lung Cancer
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Complete Surgical Resection|Circulating Tumor DNA
Interventions: DRUG: Nivolumab|DRUG: Pemetrexed|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Carboplatin|PROCEDURE: ctDNA blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of LNF1901 in Advanced Malignant Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Malignant Tumors
Interventions: DRUG: LNF1901 Monoclonal Antibody Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proximal Intestinal Obstruction Syndrome (PIOS) in a Patient With Cystic Fibrosis: A New Syndrome
Status: COMPLETED
Conditions: Cystic Fibrosis|Bowel Obstruction|Distal Intestinal Obstruction Syndrome
Interventions: OTHER: Diagnostic laparoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Alternative Neoadjuvant Chemotherapy in Resectable and Borderline Resectable Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Gemcitabine|DRUG: nab paclitaxel|DRUG: Onivyde|DRUG: Leucovorin|DRUG: 5-fu
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rationales for Wound Care Management in Old World Cutaneous Leishmaniasis Patients
Status: COMPLETED
Conditions: Wound Healing
Interventions: PROCEDURE: Electro-thermo-coagulation|DRUG: Sodium Stibogluconate|DRUG: DAC N-055
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Adapted Physical Activity Program in Patients With Unresectable Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Unresectable Locally Advanced Cancer|Metastatic Pancreatic Cancer
Interventions: OTHER: without APA program|OTHER: APA program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Parenteral Ascorbic Acid Repletion in TransplantatIon
Status: RECRUITING
Conditions: Liver Transplant Failure and Rejection
Interventions: DRUG: Ascorbic acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Alcohol Use Reduction in Methadone Individuals With Hepatitis C Virus(HCV)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: BEHAVIORAL: Motivational Interviewing, Single - MIS|BEHAVIORAL: Motivational Interviewing Group|OTHER: Usual Care Group - UCG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: BRL49653C In Type 2 Diabetes -Comparison Study With Pioglitazone And Placebo By Monotherapy-
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Rosiglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Biliary Drainage Preceding Possible Pancreaticoduodenectomy. Are Self-expandable Metallic Stents (SEMS) Superior to Plastic Stents?
Status: WITHDRAWN
Conditions: Pancreatic Cancer
Interventions: DEVICE: Tannenbaum 10 Fr biliary stent|DEVICE: Self-expandable metallic biliary stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2b Study of DIO-902 or DIO-902 Placebo in Addition to Metformin and Atorvastatin or Atorvastatin Placebo for Type 2 Diabetes
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DRUG: DIO-902|DRUG: DIO-902|DRUG: DIO-902|DRUG: DIO-902 placebo|DRUG: DIO-902|DRUG: DIO-902|DRUG: DIO-902|DRUG: DIO-902 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact on Physical Activity of Coronary Patients in Phase 3 of a Therapeutic Consolidation Educational Program Involving a "Patient Partner" Associated With a Healthcare Professional.
Status: RECRUITING
Conditions: Myocardial Infarction
Interventions: OTHER: Therapeutic educational consolidation program in Phase 3 of cardiac rehabilitation associating a patient & caregiver partnership|OTHER: Teleconsultation at 2 months|OTHER: Teleconsultation at 4 months|OTHER: Remote group education workshop|OTHER: Administration of self-questionnaires: IPAQ, EMAPS, the Exercise Confidence Survey, EQ-5D-5L and the Mediterranean diet adherence score.|DIAGNOSTIC_TEST: 6-minute walk test and administers the modified Borg scale at its conclusion.|DIAGNOSTIC_TEST: Biological check-up|DEVICE: Accelerometer|OTHER: Administration of a logbook
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Ability Of Inferior Vena Caval Distensibility Index With Passive Leg Raising Test To Predict Spinal Anesthesia-induced Hypotension In Elderly Patients Undergoing Infra-umbilical Surgeries. A Prospective Observational Study.
Status: NOT_YET_RECRUITING
Conditions: Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Single-port Versus Conventional Laparoscopic Colorectal Surgery
Status: UNKNOWN
Conditions: Colorectal Cancer|Inflammatory Bowel Disease|Benign Colorectal Neoplasm|Diverticular Disease
Interventions: PROCEDURE: Single-port access surgery|PROCEDURE: Conventional Laparoscopic Access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Bismuth-Containing Quadruple Therapy With Oral Vonoprazan (TAK-438) 20 mg Compared to Esomeprazole 20 mg Twice Daily in Paticipants With Helicobacter Pylori Infection
Status: COMPLETED
Conditions: Helicobacter Pylori
Interventions: DRUG: Vonoprazan|DRUG: Amoxicillin|DRUG: Clarithromycin|DRUG: Bismuth Potassium citrate|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Acute Inflammation Following Periodontal Treatment
Status: NOT_YET_RECRUITING
Conditions: Inflammation|Periodontal Diseases
Interventions: PROCEDURE: IPT+PDT|PROCEDURE: IPT+Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MEDI9197 in Subjects With Solid Tumors or CTCL and in Combination With Durvalumab and/or Palliative Radiation in Subjects With Solid Tumors
Status: TERMINATED
Conditions: Solid Tumors|CTCL|Cancer
Interventions: DRUG: MEDI9197|BIOLOGICAL: durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of the Choice of Gastric Tube Placement Sites on the Incidence of Ventilator Associated Pneumonia
Status: NOT_YET_RECRUITING
Conditions: Intubated Patient Requiring a Gastric Tube
Interventions: OTHER: nasogastric tube and orogastric tube|OTHER: orogastric tube and nasogastric tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Safety Profile, Quit and Reduction Rate After Nicorette® Gum and Patch Treatment
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: DRUG: Nicotine Gum|DRUG: Nicotine Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Explorative Trial to Evaluate the Pharmacodynamic Effect of SPD557 on Reflux Parameters in Refractory GERD Patients
Status: TERMINATED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: SPD557|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of NM8074 in Adult PNH Patients With Inadequate Response to Soliris
Status: NOT_YET_RECRUITING
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: NM8074|DRUG: Soliris
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interdisciplinary Study of Two Novel Anticonvulsants in Alcoholism
Status: TERMINATED
Conditions: Alcoholism|Alcohol Dependence|Alcohol Abuse
Interventions: DRUG: Topiramate|DRUG: Zonisamide|DRUG: Levetiracetam|DRUG: Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Alveolar Ridge Preservation by Socket Seal Techniques
Status: RECRUITING
Conditions: Alveolar Bone Resorption
Interventions: OTHER: Routine treatment of the extraction socket|PROCEDURE: Socket seal technique by a free gingival graft|PROCEDURE: Socket seal technique using a synthetic resorbable membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Pharmacodynamics of Cannabinoid-Caffeine Combinations
Status: RECRUITING
Conditions: Behavioral Pharmacology of Cannabinoids
Interventions: DRUG: Oral Placebo|DRUG: Oral THC|DRUG: Oral CBD|DRUG: Oral Caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Extension Study of Entacapone in Patients With Parkinson's Disease With End-of-dose Wearing-off. This Study is Not Recruiting in the United States
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Entacapone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 21 Day Cumulative Skin Irritation of RUT058-60
Status: COMPLETED
Conditions: Irritation/Irritant
Interventions: DRUG: Hypochlorous acid solution 106 mg/L|DRUG: 0.1% (w/v) Sodium Lauryl Sulfate|DRUG: 0.9% Physiological Saline, USP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: OM-85 in Paediatric Recurrent Respiratory Tract Infections With Wheezing Lower Respiratory Illness
Status: RECRUITING
Conditions: Respiratory Tract Infections|Wheezing Lower Respiratory Illness
Interventions: DRUG: OM-85|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Prevalence of BP180 and BP230 Autoantibodies in the Serum of Patients With Pruritus Under Immunotherapy
Status: RECRUITING
Conditions: Patients With Chronic Pruritus for More Than 1 Month Who Have Received Immunotherapy
Interventions: BIOLOGICAL: characterisation of immunoglobulin subclasses
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Computer Guided Simultaneous Implant Placement With Tri-cortical Ridge Augmentation Using Chin Cortical Bone Struts in Anterior Atrophic Maxilla: A Case Series
Status: RECRUITING
Conditions: Ridge Augmentation
Interventions: PROCEDURE: Computer guided simultaneous implant placement with tri-cortical ridge augmentation using chin cortical bone struts
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Volume-targeted Versus Pressure-limited Noninvasive Ventilation in Patients With Acute Hypercapnic Respiratory Failure
Status: COMPLETED
Conditions: Acute Hypercapnic Respiratory Failure
Interventions: DEVICE: Volume-targeted noninvasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Severity of Right to Left Shunt in PFO Patients After Systemic Embolism
Status: UNKNOWN
Conditions: Patent Foramen Ovale|Embolism
Interventions: DIAGNOSTIC_TEST: Cardiac flow measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Risk Factors of Difficult Intubation and Related Complications in Adults in Intensive Care Units: FRIDA-Rea
Status: COMPLETED
Conditions: Difficult Intubation
Interventions: PROCEDURE: INTUBATION IN INTENSIVE CARE UNIT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 In Participants With Osteoarthritis Pain
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: LY3857210|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MTA/FS Pulpotomy for Vital Primary Incisors: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Dental Caries|Dental Pulp Exposure
Interventions: PROCEDURE: RCT Group|PROCEDURE: MTA/FS pulpotomy Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CoA-Z in Pantothenate Kinase-associated Neurodegeneration (PKAN)
Status: UNKNOWN
Conditions: Pantothenate Kinase-Associated Neurodegeneration
Interventions: OTHER: CoA-Z|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Above-knee Socket Evaluation : Sub-ischial vs Ischial Containment
Status: COMPLETED
Conditions: Lower Limb Amputation Above Knee (Injury)
Interventions: DEVICE: Socket evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aging, Geriatric Syndromes and Clonal Hematopoiesis
Status: RECRUITING
Conditions: Geriatrics|Aged|Geriatric Syndromes|Cardiovascular Diseases
Interventions: OTHER: Cognitive Assessment|OTHER: Activities of Daily Living Questionnaire|OTHER: Instrumental Activities of Daily Living, subscale of the OARS|OTHER: Karnofsky Self-reported Performance Rating Scale|OTHER: Number of Falls|OTHER: Physical Health Section, subscale of the OARS|OTHER: MOS Social Activity Survey|OTHER: Unintentional Weight Loss|GENETIC: Peripheral Blood Draw|GENETIC: Buccal Swab|OTHER: Heart Health and Smoking History from BRFSS questionnaire|OTHER: Gait Speed|OTHER: Grip Strength|OTHER: Height and Weight measurements|OTHER: Blood pressure measurement|PROCEDURE: Optional bone marrow biopsy|PROCEDURE: Blood draw for trauma measurements
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study of Single-port Robot-assisted Nipple-sparing Mastectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Nipple-sparing Mastectomy|Prophylactic Mastectomy|Breast Cancer|BRCA1 Mutation|BRCA2 Mutation
Interventions: DEVICE: da Vinci SPⓇ Single-port System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Anti-CHIKV Hyperimmune Intravenous Immunoglobulins
Status: UNKNOWN
Conditions: Chikungunya Virus Infection
Interventions: BIOLOGICAL: anti-CHIKV hyperimmune immunoglobulins
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Using Double Gloves on Perforation in Orthopedic Surgery
Status: COMPLETED
Conditions: Puncture|Surgical Gloves|Orthopedic Disorder
Interventions: OTHER: double surgical gloves|OTHER: single surgical gloves
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: First-line Treatment for Unresectable Locally Advanced Distal Cholangiocarcinoma Combining Radiotherapy and HAIC
Status: RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: RADIATION: Radiotherapy|DRUG: HAIC (GEMOX)|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Asymptomatic SARS-Cov2 Infected Patients by Detection Dogs: "Proof of Concept" Study (CoviDetectionDog)-Covid-19
Status: COMPLETED
Conditions: Infection by SARS-COV-2|Healthy Controls
Interventions: OTHER: Body odor samples|OTHER: Body odor samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Hypocholesterolemic Effect of Fibracep
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: FIBRACEP|DIETARY_SUPPLEMENT: INSOLUBLE|DIETARY_SUPPLEMENT: SOLUBLE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Orexigenic Therapy With Delta-9-tetrahydrocannabinol in Advanced Cancer Patients With Chemosensory Abnormalities - a Pilot Study
Status: COMPLETED
Conditions: Cancer|Anorexia|Taste Disorders|Olfactory Disorders
Interventions: DRUG: Marinol (Dronabinol)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Functional Vision Outcomes: DAILIES TOTAL1 Toric vs. Spherical Lenses in Asian Astigmatic Patients
Status: RECRUITING
Conditions: Comparative Effectiveness Research
Interventions: DIAGNOSTIC_TEST: Visual acuity test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open-label Study of IMGN779 in Adult Patients With Relapsed/Refractory CD33-positive Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: IMGN779
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adebrelimab With or Without SHR-8068 in Combination With Cisplatin Plus Gemcitabine as First-line Treatment in Patients With Advanced Biliary Tract Cancer
Status: RECRUITING
Conditions: Biliary Tract Cancer
Interventions: DRUG: SHR-8068|DRUG: Adebrelimab|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Adalimumab and Methotrexate (MTX) Versus MTX Monotherapy in Subjects With Early Rheumatoid Arthritis
Status: COMPLETED
Conditions: Early Rheumatoid Arthritis
Interventions: BIOLOGICAL: Adalimumab|DRUG: Methotrexate|BIOLOGICAL: Adalimumab placebo|DRUG: Methotrexate placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Neo-Kidney Augment (NKA) in Patients With Type 2 Diabetes and Chronic Kidney Disease (CKD)
Status: TERMINATED
Conditions: Chronic Kidney Disease|Type 2 Diabetes
Interventions: BIOLOGICAL: Neo-Kidney Augment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stress Reduction to Reduce Risk for Arrhythmia in ICD Patients (The RISTA Study)
Status: COMPLETED
Conditions: Arrhythmias, Cardiac
Interventions: BEHAVIORAL: Stress reduction treatment (SRT) program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Children With Aluminium Contact Allergy: Oral Exposure Study
Status: COMPLETED
Conditions: Contact Dermatitis|Contact Allergy|Aluminum Allergy
Interventions: DIETARY_SUPPLEMENT: sodium aluminium phospate (SALP)|DIETARY_SUPPLEMENT: Aluminium-free pancake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: TRAP Study: Testosterone for Androgen Receptor Polymorphism
Status: NOT_YET_RECRUITING
Conditions: Fertility Disorders
Interventions: DRUG: Transdermal Gel in Sachet Dosage Form|DRUG: No pretreatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Topiramate on Etonogestrel Concentrations in Contraceptive Implant Users
Status: COMPLETED
Conditions: Migraine|Migraine;Menstrual|Contraception
Interventions: DRUG: Topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Has Ultrasound-guided Hydrorelease of Coracohumeral Ligamet Additional Benefit in Patients With Adhesive Capsulitis Receiving Ultrasound-guided Shoulder Hyrodilatation?
Status: RECRUITING
Conditions: Adhesive Capsulitis
Interventions: DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ruxolitinib in Pancreatic Cancer Patients
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: Ruxolitinib|DRUG: Placebo|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Meningococcal Vaccine GSK 134612 Co-administered With Pneumococcal and DTPa-HBV-IPV/Hib Vaccines
Status: COMPLETED
Conditions: Infections, Meningococcal|Meningococcal Vaccines
Interventions: BIOLOGICAL: Nimenrix™|BIOLOGICAL: Menjugate®|BIOLOGICAL: NeisVac-CTM|BIOLOGICAL: Infanrix™ hexa|BIOLOGICAL: Synflorix™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Characterization of Corneal Epithelial Changes in Participants Treated With Belantamab Mafodotin
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Belantamab mafodotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Celecoxib in Treating Patients With Cervical Intraepithelial Neoplasia
Status: COMPLETED
Conditions: Cervical Carcinoma|Cervical Intraepithelial Neoplasia Grade 2/3|Stage 0 Cervical Cancer
Interventions: DRUG: Celecoxib|OTHER: Laboratory Biomarker Analysis|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Vaccine Therapy With or Without Sargramostim in Treating Patients Who Have Undergone Surgery for Melanoma
Status: COMPLETED
Conditions: Ciliary Body and Choroid Melanoma, Medium/Large Size|Extraocular Extension Melanoma|Iris Melanoma|Stage IIB Melanoma|Stage IIC Melanoma|Stage IIIA Melanoma|Stage IIIB Melanoma|Stage IIIC Melanoma|Stage IV Melanoma
Interventions: BIOLOGICAL: tyrosinase peptide|BIOLOGICAL: gp100 antigen|BIOLOGICAL: MART-1 antigen|BIOLOGICAL: incomplete Freund's adjuvant|DRUG: Montanide ISA 51 VG|BIOLOGICAL: sargramostim|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Morphine or Fentanyl for Refractory Dyspnea in COPD
Status: ACTIVE_NOT_RECRUITING
Conditions: COPD
Interventions: DRUG: Fentanyl|DRUG: Morphine Retard|DRUG: Placebo patch|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interplay Between Organic Anion Transporting Polypeptide (OATP) Transporters Transporters and CYP2C9 in Glyburide Pharmacokinetics (PK)
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: glyburide|DRUG: glyburide + fluconazole|DRUG: glyburide + rifampin|DRUG: glyburide + fluconazole + rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Allogeneic HSCT in MDS Patients Based on Risk According to R-IPSS
Status: RECRUITING
Conditions: MDS and Allogeneic Stem Cell Transplantation
Interventions: OTHER: MDS and AlloHSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lutein Bioavailability From Fresh and Dried Beverages
Status: COMPLETED
Conditions: Macular Pigment
Interventions: DIETARY_SUPPLEMENT: Fresh lutein-enriched egg-yolk beverage|DIETARY_SUPPLEMENT: Dried-1 lutein-enriched egg-yolk beverage|DIETARY_SUPPLEMENT: Dried-2 lutein-enriched egg-yolk beverage|DIETARY_SUPPLEMENT: Placebo beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Psyllium-enriched Hamburger Meatballs: Effects on Postprandial Lipidemia, Glycemia, Appetite, and Food Intake
Status: COMPLETED
Conditions: Nutrition, Healthy|Appetitive Behavior|Food Preferences|Obesity|Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Psyllium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Extended-release Guanfacine Hydrochloride in Children/Adolescents With Attention-deficit/Hyperactivity
Status: COMPLETED
Conditions: Attention Deficit Disorder
Interventions: DRUG: Extended-release Guanfacine Hydrochloride (SPD503)|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation Associated With Pilates in Low Back Pain
Status: NOT_YET_RECRUITING
Conditions: Low Back Pain|Transcranial Direct Current Stimulation
Interventions: OTHER: Stimulation and exercise group|OTHER: Exercise and sham stimulation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate Safety and Efficacy of P276-00 in Subjects With Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Relapsed and/or Refractory Multiple Myeloma
Interventions: DRUG: P276-00
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Electrical Stimulation on Patellofemoral Pain
Status: UNKNOWN
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Neuromuscular electrical stimulation|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Androgenetic Alopecia in Males and Females
Status: COMPLETED
Conditions: Androgenetic Alopecia
Interventions: DEVICE: TopHat 655 rejuvenation system|DEVICE: Laser and/or Light Hair Rejuvenation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STA363 in the Treatment of Lumbar Disc Herniation
Status: RECRUITING
Conditions: Lumbar Disc Herniation
Interventions: DRUG: Lactic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ultrasound-enhanced Bee Venom on Selected Post Inguinal Hernioplasty Complications
Status: COMPLETED
Conditions: Complications; C, Intestinal (Internal)
Interventions: COMBINATION_PRODUCT: bee venom gel phonophoresis|DEVICE: low intensity ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Non-alcoholic Steatohepatitis (NASH) Patients With Vitamin D
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis (NASH)
Interventions: DRUG: Vitamin D3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare the Pharmacokinetics of Traclear 62.5 mg Tablets and HGP1206 125mg 1 Tablet in Healthy Male Volunteers
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: HGP1206|DRUG: Traclear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Time-dependent Amiodarone Treatment in Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Intravenous amiodarone(1)|DRUG: Intravenous amiodarone(2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Open Label Study Evaluating The Use Of Combination Therapy Of Ezetimibe And Statins In Patients With Dyslipidemia In Colombia (0653-141)(COMPLETED)
Status: COMPLETED
Conditions: Lipid Metabolism Disorder
Interventions: DRUG: ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Clinical Evaluation of BD NRFit™ Devices and Accessories.
Status: COMPLETED
Conditions: Anesthesia|Analgesia
Interventions: DEVICE: BD NRFit™ Spinal Needles, BD NRFit™ Spinal Introducer Needles, and BD NRFit™ Syringes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Healthy Volunteer Safety Study of Pyronaridine Tetraphosphate Taken in Combination With Piperaquine Tetraphosphate
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pyronaridine Tetraphosphate|DRUG: Piperaquine tetraphosphate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Prevention of Unmitigated Chemotherapy-induced Emesis
Status: WITHDRAWN
Conditions: Chemotherapy-induced Nausea and Vomiting|Nausea Post Chemotherapy
Interventions: DEVICE: Otoband|DEVICE: Placebo device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Web-Assisted Interactive Nurse Program in Mastectomy Patients: A Mixed Method Study
Status: COMPLETED
Conditions: Web Based Intervention|Mastectomy|Illness Perception|Nursing Caries
Interventions: BEHAVIORAL: Web-assisted patient education intervention designed according to the self-regulation model|BEHAVIORAL: The website where the mastectomy patients handbook
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chemotherapy in Patients With Relapsed Small Cell Lung Cancer in Combination With Allopurinol and MycoPhenolate (CLAMP Trial)
Status: RECRUITING
Conditions: Small-cell Lung Cancer|Small Cell Lung Carcinoma
Interventions: DRUG: Mycophenolate Mofetil|DRUG: Allopurinol|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Hypoxia on FMISO PET to Response to Lu-177 PSMA Treatment
Status: RECRUITING
Conditions: Prostatic Neoplasms|Hypoxia
Interventions: DIAGNOSTIC_TEST: F-MISO PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bakri Balloon Plus Tranexamic Acid During Cesarean Delivery for Placenta Previa
Status: UNKNOWN
Conditions: Placenta Previa
Interventions: DRUG: Tranexamic Acid|DRUG: placebo to TA|DEVICE: Bakri Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: New Application of Sequential in Vitro Muturation System for Infertility Patients With Polycystic Ovary Syndrome
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome|Infertility
Interventions: DRUG: sequential IVM system|PROCEDURE: intracytoplasmic sperm injection (ICSI)|PROCEDURE: Thawed embryo transfer (TET)|DRUG: traditional IVM system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Forced Diuresis on the Residual Fragment Rate After Flexible Ureteroscopy for Destruction of Kidney Stones With Laser
Status: NOT_YET_RECRUITING
Conditions: Kidney Stone
Interventions: DRUG: Furosemide 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Drug Interactions Between a Hormonal Emergency Contraception and an HIV Medication
Status: COMPLETED
Conditions: HIV Infections|Contraception|Pharmacokinetics
Interventions: DRUG: levonorgestrel, efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Surgical Approach to the Management of Type II Diabetes Mellitus in Patients With a BMI Between 25-35 kg/m2
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: PROCEDURE: Sleeve Gastrectomy and Ileal transposition|DIETARY_SUPPLEMENT: dietary and medical management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NKG2D-based CAR T-cells Immunotherapy for Patient With r/r NKG2DL+ Solid Tumors
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Glioblastoma|Medulloblastoma|Colon Cancer
Interventions: BIOLOGICAL: NKG2D-based CAR T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Macular Degeneration and Aging Study
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: BEHAVIORAL: Preventive Problem-Solving Training|BEHAVIORAL: Life and Health Review
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase II Study Looking at Moderate to Severe Osteoarthritis Knee Pain
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: RN624 (PF-04383119)|DRUG: RN624 (PF-04383119)|DRUG: RN624 (PF-04383119)|DRUG: RN624 (PF-04383119)|DRUG: RN624 (PF-04383119)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Patient Preference Trial on Heat-sensitive Moxibustion for Primary Hypertension in Community
Status: COMPLETED
Conditions: Primary Hypertension
Interventions: OTHER: Heat-sensitive moxibustion plus original antihypertensive treatment (compulsively randomized arm)|DRUG: Original antihypertensive treatment (compulsively randomized arm)|OTHER: Heat-sensitive moxibustion plus antihypertensive treatment (voluntarily randomized arm)|DRUG: Original antihypertensive treatment (voluntarily randomized arm)|OTHER: Heat-sensitive moxibustion plus original antihypertensive treatment (preference selection arm)|DRUG: Original antihypertensive treatment (preference selection arm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of GLYX-13 in Subjects With Inadequate/Partial Response to Antidepressants
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: GLYX-13 5 mg/kg|DRUG: GLYX-13 10 mg/kg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Naltrexone and Memantine Effects on Alcohol Drinking Behaviors
Status: COMPLETED
Conditions: Alcohol Drinking
Interventions: DRUG: Naltrexone and memantine first|DRUG: Naltrexone and Placebo first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Physical Training and Heart Rate Variability in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: OTHER: Physical Exercise Training Program Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 18F-FAPI PET Imaging in Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: 18F-FAPI|18F-FDG|Pancreas Adenocarcinoma|Diagnosis|Staging
Interventions: DRUG: 18F-FAPI|DRUG: 18F-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Transcranial Direct Current Stimulation and Early Alzheimer's Disease (tDCS-AD)
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Clostridium Butyricum in Treating Irritable Bowel Syndrome
Status: UNKNOWN
Conditions: Effect of Clostridium Butyricum in Treating Irritable Bowel Syndrome
Interventions: DRUG: Clostridium Butyricum|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oat Beta-glucan as a Supplement in Chilean Type 2 Diabetics
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Oat Beta-glucan as a Supplement in Type 2 Diabetics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Paclitaxel With Trastuzumab and Lapatinib in HER2-Positive Early Stage Breast Cancer
Status: COMPLETED
Conditions: HER2-Positive Early Stage Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Trastuzumab|DRUG: Lapatinib|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib in Treating Patients With Relapsed or Refractory Follicular Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Grade 3a Follicular Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Refractory Follicular Lymphoma
Interventions: DRUG: Ibrutinib|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Application of Narrative Medicine Combined With Case-Based Learning in the Standardized Training of General Practice Residents
Status: COMPLETED
Conditions: Narrative Medicine|Case-based Learning
Interventions: BEHAVIORAL: narrative medicine training combined with CBL training|BEHAVIORAL: CBL training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mechanisms and Innovations in Cardiac Resynchronisation Therapy
Status: COMPLETED
Conditions: Heart Failure|Left Ventricular Systolic Dysfunction|Left Bundle-Branch Block|Right Bundle-Branch Block|Non-Specific Intraventricular Conduction Defect
Interventions: DEVICE: His-bundle pacing.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MAintain the Efficacy and Safety in Treatment of Schizophrenia After Switching to Long-acTing Injectable aRipiprazole From Oral Atypical Antipsychotics
Status: COMPLETED
Conditions: Schizophrenia|Antipsychotics|Long-Acting Injection|LAI|Aripiprazole
Interventions: DRUG: Abilify maintena
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Tirofiban Administration in Patients With Aspirin and or Clopidogrel Resistance
Status: COMPLETED
Conditions: Angioplasty, Transluminal, Percutaneous Coronary
Interventions: DRUG: Tirofiban|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Parenteral Nutrition vs Conventional Fluid in Colorectal Resection in ERAS
Status: UNKNOWN
Conditions: Colon Cancer|Parenteral Nutrition|Fast-track
Interventions: DRUG: Perioperative peripheral parenteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare Ridge Preservation Technique Using Leukocyte Platelet Rich Fibrin (L-PRF) and Freeze-dried Bone Allograft (FDBA) Layered Technique vs L-PRF/FDBA and L-PRF Alone in Influencing Quantity and Quality of New Bone Formation in Grafted Extraction Sockets
Status: ACTIVE_NOT_RECRUITING
Conditions: Ridge Preservation
Interventions: PROCEDURE: Ridge preservation using L-PRF/FDBA layered technique|PROCEDURE: Ridge preservation using L-PRF/FDBA|PROCEDURE: Ridge preservation using L-PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multifactorial Intervention to Reduce Cardiovascular Disease in Type 1 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases|Heart Failure|Type 1 Diabetes|Kidney Failure
Interventions: DRUG: Aspirin tablet|DRUG: Semaglutide|DRUG: Sotagliflozin|DRUG: Finerenone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of the Combination of TQ-B211 Plus Docetaxel in Patients With HER2-positive MBC.
Status: UNKNOWN
Conditions: HER2-positive Metastatic Breast Cancer
Interventions: DRUG: TQ-B211|DRUG: Herceptin®|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Muscle Training in Difficult to Wean Patients
Status: COMPLETED
Conditions: Weaning Failure
Interventions: PROCEDURE: Inspiratory Muscle Training|PROCEDURE: Endurance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardioprotective Properties of Natural Anti-Platelet Activating Factor Extract From Winery By-products in Healthy Women
Status: UNKNOWN
Conditions: Platelet Aggregation and Inflammation
Interventions: BEHAVIORAL: Supplement|BEHAVIORAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT