pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Measuring the Influence of Maxillary Obturator Prosthesis on Facial Morphology in Patient With Unilateral Maxillary Defects Using Stereophotogrammetry
Status: UNKNOWN
Conditions: Facial Asymmetry
Interventions: DEVICE: Prosthetic intervention with maxillary obturator prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olive Leaf Extract, Meta-inflammation, Anxiety, and Excess Weight
Status: ENROLLING_BY_INVITATION
Conditions: Women|Excess Weight|Anxiety Disorders
Interventions: DIETARY_SUPPLEMENT: Olive Leaf Extract (OLE)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preoperative Folfirinox, Radiation Therapy for Resectable Adenocarcinoma of the Pancreas
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Irinotecan|DRUG: 5-FU|DRUG: Gemcitabine|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trametinib in Treating Patients With Advanced Cancer With or Without Hepatic Dysfunction
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Metastatic Malignant Neoplasm in the Liver|Metastatic Malignant Solid Neoplasm|Unresectable Solid Neoplasm
Interventions: DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three M Study (Malabsorption, Microbiota, Mini-Gastric Bypass)
Status: COMPLETED
Conditions: Obesity (Disorder)
Interventions: PROCEDURE: Mini Gastric Bypass|PROCEDURE: Roux en Y Gastric Bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: DIMES - DIgital MEdicine Study for Adults With Schizophrenia, Bipolar I Disorder, or Major Depression Currently Using Aripiprazole
Status: UNKNOWN
Conditions: Schizophrenia|Major Depressive Disorder|Bi-Polar Disorder|Schizo Affective Disorder
Interventions: COMBINATION_PRODUCT: ABILIFY MYCITE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Modifying Highly Calcified Coronary Lesions on Coronary Microcirculation
Status: ENROLLING_BY_INVITATION
Conditions: Coronary Artery Calcification|Ischemic Heart Disease|Non-ST-Segment Elevation Myocardial Infarction (NSTEMI)|Coronary Artery Disease|Angina, Unstable|Tomography, Optical Coherence
Interventions: DEVICE: Lithotripsy|DEVICE: Orbital atherectomy|DEVICE: High-pressure non-compliant balloon|DEVICE: Optical coherence tomography|DEVICE: Coroventis Coroflow Cardiovascular System and PressureWire™ X Guidewire
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Supervised Treatment of Schizophrenia, a Randomized Controlled Trial.
Status: UNKNOWN
Conditions: Schizophrenia|Schizoaffective Disorders
Interventions: BEHAVIORAL: Supervised Treatment of Schizophrenia by a family member
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study With the Medical Device PowerSpiral for Endoscopic Retrograde Cholangio-Pancreatography (ERCP)
Status: TERMINATED
Conditions: Cholangiopancreatography, Endoscopic Retrograde
Interventions: DEVICE: Endoscopic Retrograde Cholangio-Pancreatography (ERCP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Tac-Expressing Cutaneous T-Cell Lymphoma (CTCL) and Adult T-Cell Leukemia (ATL) With Yttrium-90 Radiolabeled Anti-Tac
Status: COMPLETED
Conditions: Leukemia, T-Cell|Lymphoma, T-Cell, Cutaneous
Interventions: DRUG: Yttrium-90 radiolabeled anti-Tac antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Open-label, Multli-center, Phase 1b/2a Clinical Trial Designed to Evaluate the Safety and Efficacy of Iontophoretic Dexamethasone Phosphate Ophthalmic Solution in Patients With Macular Edema
Status: TERMINATED
Conditions: Macular Edema
Interventions: DRUG: Dexamethasone Phosphate Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prediction of Treatment Response at 6 Months by Combinatorial Analysis of Serum Biomarkers in Biotherapy Naive SpA
Status: COMPLETED
Conditions: Spondylitis, Ankylosing
Interventions: DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effect of Microneedling, Bimatoprost and Excimer in Vitiligo Treatment
Status: COMPLETED
Conditions: Vitiligo
Interventions: DRUG: Bimatoprost|DEVICE: Excimer laser|DEVICE: Microneedling with a dermaroller
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine Infusion for Neuropathic Pain in Brachial Plexus Injuries
Status: ENROLLING_BY_INVITATION
Conditions: Brachial Plexus Injury
Interventions: DRUG: Ketamine Infustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Potential Role of a Novel Quadrate Combination Therapy Mifepristone(Antiprogestrone), Tamoxifen, Retinoic Acid and Cannabidiol ( Selective Cyp 26 Inhibitor) for Treating Early Breast Cancer.
Status: UNKNOWN
Conditions: Breast Cancer Female
Interventions: DRUG: All trans-retinoic acid|DRUG: 13-Cis Retinoic Acid plus Tocopherol|DRUG: Mifepristone|DRUG: Cannabidiol|DRUG: 9 cis retinoic acid|DRUG: Tamoxifen|DRUG: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAV Regimen Bridging to HSCT for R/R AL
Status: RECRUITING
Conditions: Acute Leukemia, Relapsed|Acute Leukemia Refractory
Interventions: PROCEDURE: CAV regimen bridging to HSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study of LPM3480392 at Different Infusion Rates in Chinese Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LPM3480392
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stepping-Up: Partnering With the Community to Prevent Early Mobility Decline
Status: RECRUITING
Conditions: Mobility Limitation
Interventions: OTHER: Stepping-Up|OTHER: Telephone-Based Coaching Walking Program|OTHER: Chair-Based Yoga Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability and Pharmacokinetics of ALD1910 in Healthy Men and Woman
Status: COMPLETED
Conditions: Migraine
Interventions: BIOLOGICAL: ALD1910|BIOLOGICAL: Sumatriptan|BIOLOGICAL: ALD1910
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lumbar Drainage in Subarachnoid Haemorrhage
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage
Interventions: DEVICE: Lumbar Drain (Medtronic lumbar drainage system)|OTHER: No lumbar drain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of PUR118 on Ozone Induced Airway Inflammation in Healthy Normal Volunteers
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: PUR118
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Of SU011248 In Combination With Paclitaxel/Carboplatin In Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: carboplatin + SU011248 (sunitinib) + paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Immunogenicity and Safety Profile of CSL Limited's Influenza Virus Vaccine Compared to a US Licensed Comparator Influenza Virus Vaccine in a Pediatric Population
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: CSL's Influenza Virus Vaccine (Afluria)|BIOLOGICAL: Influenza Virus Vaccine (Fluzone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pulmonary Optical Coherence Tomography in COVID-19 Patients
Status: COMPLETED
Conditions: Covid19|Pulmonary Embolism
Interventions: DIAGNOSTIC_TEST: Optical Coherence Tomography (OCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: International Study to Evaluate Two Programs of Support for Patients With Advanced Cancer and Their Families
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: OTHER: FOCUS+ (face-to-face nurse-led intervention)|OTHER: iFOCUS (web-based intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Power Injectable Versus a Non-Power Injectable, Upper Arm, TIVAD for Chemotherapy
Status: COMPLETED
Conditions: Malignancy
Interventions: DEVICE: Power Injectable Port (AngioDynamics Smart Port CT Mini)|DEVICE: Non-Power Injectable Port (Cook Vital Mini Port)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Smart-glasses During the Ultrasound-guided Radial Arterial Catheterization in Pediatric Patients by Trainees
Status: COMPLETED
Conditions: Arterial Line
Interventions: DEVICE: Smart glasses|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Dapagliflozin, Lobeglitazone, and Its Combination in Efficacy and Safety
Status: RECRUITING
Conditions: Diabetes Type 2
Interventions: DRUG: Dapagliflozin 10mg Tab|DRUG: Lobeglitazone 0.5 mg|DRUG: Dapagliflozin + Lobeglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Based Cognitive Therapy: Efficacy and fMRI-based Response Predictors in a Group of OCD Patients
Status: UNKNOWN
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Mindfulness Based Intervention|DRUG: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of 15g Daily Consumption of NUTRIOSE on Healthy Volunteers Microbiota.
Status: COMPLETED
Conditions: Microbiota|Dietary Fibers
Interventions: DIETARY_SUPPLEMENT: NUTRIOSE FB06|DIETARY_SUPPLEMENT: GLUCIDEX 21
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Utilization of Very Low Calorie Diet in Obese General Surgery Patients
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: DIETARY_SUPPLEMENT: Very low calorie diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Augmented Berlin-Frankfurt-Munster (BFM) Therapy for Adolescent/Young Adults With Acute Lymphoblastic Leukemia or Acute Lymphoblastic Lymphoma
Status: COMPLETED
Conditions: Lymphoblastic Leukemia|Lymphoblastic Lymphoma
Interventions: DRUG: Daunorubicin|DRUG: Vincristine|DRUG: PEG-asparaginase|DRUG: Intrathecal Methotrexate|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Mercaptopurine|DRUG: Methotrexate|DRUG: Doxorubicin|DRUG: Thioguanine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Theory of Meleis on Women's Adaptation to Motherhood and Perceptions of Newborn Baby
Status: COMPLETED
Conditions: Newborn|Prenatal Care|Nursing Caries
Interventions: OTHER: Structured education and follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Neuroprotective Effect of Remote Ischemic Preconditioning on Ischemic Cerebral Vascular Disease
Status: COMPLETED
Conditions: Cerebrovascular Disease
Interventions: PROCEDURE: Remote ischemic preconditioning (RIPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Pneumonia on Delayed Cerebral Ischemia After Subarachnoid Hemorrhage . SAH-CIP (SubArrachnoid Hemorrhage - Cerebral Infarction Pneumonia)
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage|Pneumonia, Bacterial
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Superiority of ArTiMist Versus Quinine in Children With Severe Malaria
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria
Interventions: DRUG: Artemether Sublingual Spray|DRUG: Quinine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QVA149 Versus Fluticasone/Salmeterol in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: indacaterol and glycopyrronium (QVA149)|DRUG: Placebo to fluticasone/salmeterol|DRUG: fluticasone/salmeterol|DRUG: Placebo to indacaterol and glycopyrronium (QVA149)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Safety and Immunogenicity of ADACEL® Vaccine in Persons 65 Years of Age and Older
Status: COMPLETED
Conditions: Pertussis|Tetanus|Diphtheria
Interventions: BIOLOGICAL: ADACEL®: Tetanus, Reduced Diphtheria and Acellular Pertussis Adsorbed|BIOLOGICAL: DECAVAC®: Tetanus and Diphtheria Toxoids Adsorbed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL919 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participant
Interventions: DRUG: DNL919|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Versus Paravertebral in Pediatric PCNL
Status: COMPLETED
Conditions: Renal Stone|Percutaneous|Nephrolithotomy
Interventions: PROCEDURE: Erector spinae plane block|PROCEDURE: Paravertebral block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spaeth/Richman Contrast Sensitivity Test
Status: COMPLETED
Conditions: Glaucoma
Interventions: DIAGNOSTIC_TEST: Spaeth/Richman Contrast Sensitivity Test|DIAGNOSTIC_TEST: Pelli-Robson Contrast Sensitivity Chart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fosbretabulin or Placebo in Combination With Carboplatin/Paclitaxel in Anaplastic Thyroid Cancer
Status: WITHDRAWN
Conditions: Anaplastic Thyroid Cancer
Interventions: DRUG: Fosbretabulin + paclitaxel + carboplatin|DRUG: Placebo + paclitaxel + carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Modeling Macrophages Activation Pattern in X-linked Adrenoleukodystrophy, Metachromatic Leukodystrophy and Adult Onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia
Status: RECRUITING
Conditions: Adrenoleukodystrophy|Adrenomyeloneuropathy|Metachromatic Leukodystrophy|Adult-Onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia
Interventions: DIAGNOSTIC_TEST: Blood sample collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nozin in Preventing Respiratory Viral Infections in Patients Undergoing Stem Cell Transplant, PREV-NOSE STUDY
Status: SUSPENDED
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm|Solid Neoplasm
Interventions: DRUG: Nozin|OTHER: Best Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability of GX-P1 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Autoimmune Diseases
Interventions: DRUG: GX-P1 or Placebo (dose level 1)|DRUG: GX-P1 or Placebo (dose level 2)|DRUG: GX-P1 or Placebo (dose level 3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Curcumin in Preventing Gastric Cancer in Patients With Chronic Atrophic Gastritis or Gastric Intestinal Metaplasia
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Atrophic Gastritis
Interventions: DRUG: Curcumin|OTHER: Laboratory Biomarker Analysis|OTHER: Placebo Administration|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Study of GW642444M in Healthy Japanese Male Subjects
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GW642444|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Glecaprevir/Pibrentasvir (ABT-493/ABT-530) in Treatment-Naive and Treatment-Experienced Asian Adults With Chronic Hepatitis C Virus Genotype (GT) 1 to GT6 Infection With Compensated Cirrhosis and With or Without Human Immunodeficiency Virus Co-Infection
Status: COMPLETED
Conditions: Hepatitis C Virus (HCV)
Interventions: DRUG: Glecaprevir/Pibrentasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BMS-986012 in Relapsed/Refractory SCLC
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: BIOLOGICAL: BMS-986012 (anti-fucosyl-GM1)|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of COVID-19 Infection on Beta-cell Function in Euglycemic Patients
Status: COMPLETED
Conditions: COVID19|BETA-CELL FUNCTION
Interventions: DIAGNOSTIC_TEST: Stimulation test with arginine infusion in order to verify the possible existence of damage to the beta cell function induced by COVID-19 infection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: LLETZ With Videocolposcopy Versus LLETZ With Binocular Colposcopy
Status: COMPLETED
Conditions: Uterine Cervical Dysplasia
Interventions: DEVICE: LLETZ with videocolposcope|DEVICE: LLETZ with binocular colposcope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of VX-150 in Subjects With Acute Pain Following Bunionectomy
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: VX-150|DRUG: HB/APAP|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bilateral Comparison Study of Elidel 1% and Hylatopic Plus Emollient Foam for the Treatment of Subjects With Atopic Dermatitis
Status: COMPLETED
Conditions: Eczema|Atopic Dermatitis
Interventions: DEVICE: Elidel (pimecrolimus cream, 1%) Hylatopic Plus Emollient Foam (non-medicated device)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Cilostazol and Probucol to Assess Their Effects on Atherosclerosis Related Biomarker
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Arteriosclerosis Obliterans
Interventions: DRUG: Cilostazol|DRUG: Probucol|DRUG: Cilostazol+Probucol|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 52-Week Study of Bicifadine in Patients With Chronic Neuropathic Pain Associated With Diabetic Peripheral Neuropathy
Status: TERMINATED
Conditions: Chronic Peripheral Neuropathy Pain in Diabetics
Interventions: DRUG: Bicifadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Central Programming in Patients With a Bionic Hand After Traumatic Brachial Plexus Injury
Status: COMPLETED
Conditions: Brachial Plexus Neuropathies|Traumatic Brachial Plexus Lesion|Bionic Hand Reconstruction
Interventions: DIAGNOSTIC_TEST: MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ondansetron for the Treatment of Heavy Drinking Among Emerging Adults
Status: TERMINATED
Conditions: Alcohol Abuse|Alcoholism
Interventions: DRUG: Ondansetron|DRUG: Placebo|BEHAVIORAL: BASICS Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 3D, Dynamic and Mechanically-informed Decision Making in AIS
Status: ENROLLING_BY_INVITATION
Conditions: Adolescent Idiopathic Scoliosis
Interventions: PROCEDURE: Adolescent Idiopathic Scoliosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BLAST MRD AML-1: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 1- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Intensive Chemotherapy as Frontline Therapy in Patients With Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Acute Myeloid Leukemia Post Cytotoxic Therapy|Secondary Acute Myeloid Leukemia
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|DRUG: Cytarabine|DRUG: Daunorubicin Hydrochloride|PROCEDURE: Echocardiography|PROCEDURE: Hematopoietic Cell Transplantation|DRUG: Idarubicin Hydrochloride|PROCEDURE: Multigated Acquisition Scan|BIOLOGICAL: Pembrolizumab|PROCEDURE: Punch Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Neoadjuvant Induction and Consolidation CapeOX Plus IMRT With Capecitabine for MRI Defined High-risk Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Capecitabine|RADIATION: Intensity modulated radiotherapy|PROCEDURE: Total mesorectal excision
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IVIg for Demyelination in Diabetes Mellitus
Status: UNKNOWN
Conditions: Peripheral Neuropathy|Diabetes Mellitus|Chronic Inflammatory Demyelinating Polyneuropathy
Interventions: DRUG: 10% intravenous immunoglobulin (IVIg)|DRUG: 0.9% sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementing Prescriber-Pharmacist Collaborative Care for Evidence-based Anticoagulant Use
Status: RECRUITING
Conditions: Pulmonary Embolism|Venous Thromboembolism|Atrial Fibrillation
Interventions: BEHAVIORAL: New-prescription Alert|BEHAVIORAL: New-prescription Alert with referral option|BEHAVIORAL: Existing-prescription notification to prescriber|BEHAVIORAL: Existing-prescription notification to pharmacist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Randomized Multicenter Trial With SU11248 Evaluating Dosage,Tolerability,Toxicity and Effectiveness of a Multitargeted Receptor Tyrosine Kinase Inhibitor
Status: COMPLETED
Conditions: Platinum Refractory Epithelial Ovarian Cancer|Primary Cancer of the Peritoneum|Cancer of the Fallopian Tube
Interventions: DRUG: Sunitinib|DRUG: SUNITINIB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Multicenter Longitudinal Cohort Study of the Mymobility Platform
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee|Osteoarthritis, Hip
Interventions: OTHER: mymobility with Apple Watch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Peritoneal Diffusion and Efficacy of Antibiotic Therapy in Pediatric Peritonitis
Status: UNKNOWN
Conditions: Peritonitis|Appendicitis|Children, Only|Antibiotic Toxicity
Interventions: OTHER: Dosage of serum and peritoneal of the betalactam used for antibiotic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Triburter on Respiratory Muscle Function in Patients After CABG in Cardiac Rehabilitation Phase II
Status: UNKNOWN
Conditions: Thoracic Surgery|Postoperative Period|Weakness, Muscle
Interventions: DEVICE: Triburter|DEVICE: Incentive spirometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methylphenidate for Treating Children With ADHD and Tourette Syndrome
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity|Tourette Syndrome
Interventions: DRUG: Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trials of Continuous Oxygen Therapy Combined With Blue Light Deprivation in the Treatment of Retinitis Pigmentosa
Status: NOT_YET_RECRUITING
Conditions: Retinitis Pigmentosa
Interventions: DRUG: Continuous oxygen|DEVICE: blue light-absorbing sunglasses|DRUG: Compound thrombosis capsule sig: 1.5g/tid|DRUG: Ginkgo biloba pills sig: 300mg/tid;|DRUG: Vitamin B sig: 10mg/tid|DRUG: Vitamin AD sig: 1 tablet/tid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Dendritic Cell Content and T-Cell Phenotype Between Granulocyte Colony-Stimulating Factor (G-CSF) or G-CSF + Granulocyte Macrophage (GM)-CSF
Status: TERMINATED
Conditions: Hematologic Diseases
Interventions: DRUG: G-CSF|DRUG: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Early Sepsis Care Guided by the National Early Warning Score 2 in the Emergency Department
Status: COMPLETED
Conditions: Sepsis|Septic Shock
Interventions: OTHER: 2018 Surviving Sepsis Campaign Hour-1 Bundle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Rabeprazole Sodium Delayed-Release Tablets 20 mg to Aciphex® Delayed-Release Tablets 20 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rabeprazole Sodium Delayed-Release Tablets 20 mg|DRUG: Aciphex® Delayed-Release Tablets 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Gleevec Combined With Camptosar Plus Paraplatin in Previously Untreated Extensive Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Imatinib|DRUG: Irinotecan|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systemic Treatment With Everolimus for the Prevention of MACE After Bare Metal Stent Implantation
Status: UNKNOWN
Conditions: Coronary Artery Disease|Coronary Restenosis
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: PET-Directed Therapy With Pembrolizumab and Combination Chemotherapy in Treating Patients With Previously Untreated Classical Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Classical Hodgkin Lymphoma|Lymphocyte-Depleted Classical Hodgkin Lymphoma|Lymphocyte-Rich Classical Hodgkin Lymphoma|Mixed Cellularity Classical Hodgkin Lymphoma|Nodular Sclerosis Classical Hodgkin Lymphoma
Interventions: PROCEDURE: Computed Tomography|DRUG: Dacarbazine|DRUG: Doxorubicin Hydrochloride|RADIATION: Fludeoxyglucose F-18|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab|PROCEDURE: Positron Emission Tomography|DRUG: Vinblastine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sandostatin LAR and Axitinib vs Pbo in Pnts With Advanced Well-differentiated Non-pancreatic Neuroendocrine Carcinomas
Status: UNKNOWN
Conditions: Neuroendocrine Tumors|Advanced Cancer
Interventions: DRUG: Axitinib|DRUG: Sandostatin LAR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Myocardial Protective Effects of a Moderate-potassium Blood Cardioplegia in Pediatric Cardiac Surgery
Status: COMPLETED
Conditions: Congenital Heart Disease
Interventions: DRUG: MP (moderate potassium) group|DRUG: HP (High potassium) group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial With Subcutaneous Immunotherapy (SCIT) in Patients With Rhinoconjunctivitis Sensitized to Olea Europaea and Phleum Pratense
Status: COMPLETED
Conditions: Rhinoconjuntivitis
Interventions: BIOLOGICAL: allergovac polimerized (100/100)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intubation of a Pediatric Manikin in Difficult Airway by Novice Personnel: A Comparison of Glidescope and Airtraq
Status: COMPLETED
Conditions: Intubation; Difficult|Edema of the Tongue
Interventions: DEVICE: Glidescope|DEVICE: Airtraq
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetics and Safety Study of Diazepam Buccal Film (DBF) in Pediatric Subjects With Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Diazepam Buccal Film
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess Optimal Postoperative Feeding Regiments Following Pyloromyotomy
Status: COMPLETED
Conditions: Postoperative Feeding Following Pyloromyotomy
Interventions: OTHER: Incremental Feeds|OTHER: Ad lib feeds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prophylactic Cranial Irradiation in Patients With Lung Adenocarcinoma With High Risk of Brain Metastasis
Status: COMPLETED
Conditions: Lung Cancer
Interventions: RADIATION: Prophylactic Cranial Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin Injection Versus Anal Myectomy in Management of Idiopathic Constipation
Status: UNKNOWN
Conditions: Chronic Idiopathic Constipation|Functional Constipation
Interventions: DRUG: Botulinum Toxin|PROCEDURE: Anal Myectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Immunomodulatory Effect of Antrifibrinolytic (Tranexamic Acid) in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Hemorrhage
Interventions: DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Pro Resolve® Sports on Treatment of Patients With Symptomatic Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: SMP group|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy vs. Trans-Oral Surgery for HPV-Negative Oropharyngeal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Head and Neck Cancer|Oropharyngeal Squamous Cell Carcinoma
Interventions: RADIATION: Radiation|PROCEDURE: Trans-Oral Surgery (TOS) + Neck Dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Subjects' Efficacy and Experiences Using Adapalene BPO Gel in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Adapalene 0.1% and Benzoyl Peroxide 2.5% gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ocular Imaging With Spectral Domain Optical Coherence Tomography
Status: UNKNOWN
Conditions: Healthy|Myopia|Hypermetropia
Interventions: DEVICE: Spectral domain-OCT (Cirrus™ HD-OCT, Carl Zeiss Meditec AG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Epacadostat, Idarubicin and Cytarabine (EIC) in AML
Status: WITHDRAWN
Conditions: AML
Interventions: DRUG: Epacadostat|DRUG: Idarubicin|DRUG: Cytarabine|DRUG: Daunorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conversion Therapy of Sintilimab in Combination With Apatinib and Chemotherapy in Stage IV Gastric Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer Stage IV
Interventions: DRUG: sintilimab|DRUG: apatinib|DRUG: S1|DRUG: Nab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety, Tolerability, and Initial Efficacy of Recombinant Human Anti-cluster Differentiation Antigen 47 (CD47) Monoclonal Antibody Injection (IBI188) in Patients With Advanced Malignant Tumors and Lymphomas
Status: COMPLETED
Conditions: Advanced Malignancies
Interventions: BIOLOGICAL: IBI188
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Duloxetine Impact on Postoperative Pain Control and Outcomes
Status: NOT_YET_RECRUITING
Conditions: Acute Post-operative Pain|Chronic Post Operative Pain|Narcotic Use|Opioid Use|Opioid Addiction
Interventions: DRUG: Duloxetine 60 MG|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Brief Interventions on Social Media to Reduce Suicide Risk (Intervention 3)
Status: RECRUITING
Conditions: Suicide|Distress, Emotional
Interventions: BEHAVIORAL: Treatment as usual|BEHAVIORAL: Barrier Reduction Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Gluten-free Diet in PSC and IBD
Status: RECRUITING
Conditions: Primary Sclerosing Cholangitis|Ulcerative Colitis|Biliary Tract Diseases|Biliary Disease Tract|Intestinal Disease
Interventions: DIETARY_SUPPLEMENT: Gluten-free diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventive Heart Rehabilitation to Prevent Complications in Patients Undergoing Elective Open Heart Surgery
Status: RECRUITING
Conditions: Coronary (Artery); Disease|Aortic Valve Stenosis|Cardiac Surgery
Interventions: BEHAVIORAL: Pre+post-operative Cardiac rehabilitation|BEHAVIORAL: Postoperative Cardiac rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Triaging Patients With Musculoskeletal Disorders Directly to Physiotherapists at Primary Health Care Clinics.
Status: TERMINATED
Conditions: Musculoskeletal Disorders
Interventions: OTHER: Initially triaged to physiotherapist|OTHER: Initially triaged to physician
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Predictive Values of Preoperative [68Ga]Ga-PSMA-11 PET/CT in Patients With Suspected Brain Tumours of Glial Origin
Status: COMPLETED
Conditions: Glioma, Malignant|Glioma Glioblastoma Multiforme
Interventions: DIAGNOSTIC_TEST: [68Ga]Ga-PSMA-11 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Cilostazol on VEGF and Oxidative Stress Biomarkers in Hemodialysis Patients With Peripheral Vascular Disease
Status: COMPLETED
Conditions: Hemodialysis Patients|Peripheral Vascular Disease
Interventions: DRUG: Cilostazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Observational Study to Evaluate Disease Course and Outcomes in Patients Treated With Esbriet (Pirfenidone) for Idiopathic Pulmonary Fibrosis (IPF) in Canada
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effectiveness of Group-Delivered Guided Written Exposure Therapy for PTSD and Subclinical PTSD Among Chinese Adolescents : A Pilot Study
Status: RECRUITING
Conditions: PTSD
Interventions: BEHAVIORAL: Group-delivered guided written exposure therapy-revised version|BEHAVIORAL: Waiting-List (WL) condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TMC278-TiDP6-C209: A Clinical Trial in Treatment Naive HIV-1 Patients Comparing TMC278 to Efavirenz in Combination With Tenofovir + Emtricitabine.
Status: COMPLETED
Conditions: HIV Infections|HIV-1|Human Immunodeficiency Virus Type 1
Interventions: DRUG: TMC278|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patients With Refractory, Metastatic Cancer Harboring KIT Mutation or Amplification to Investigate the Clinical Efficacy and Safety of Imatinib Therapy
Status: UNKNOWN
Conditions: Advanced, Refractory Cancer
Interventions: DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Effect of Food on the Pharmacokinetics of Selumetinib (AZD6244; ARRY-142886) (Hyd-Sulfate) in Healthy Male Volunteers
Status: COMPLETED
Conditions: Solid Tumours
Interventions: DRUG: selumetinib (oral)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of N-Acetylcysteine (NAC) in Fingernail Biting
Status: COMPLETED
Conditions: Onychophagia
Interventions: DRUG: N-Acetylcysteine (NAC)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between CPAP and HFJV During One-lung Ventilation in VATS
Status: COMPLETED
Conditions: One-Lung Ventilation|Thoracic Surgery, Video-Assisted
Interventions: PROCEDURE: CPAP|PROCEDURE: HFJV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Nortriptyline in Cortical Representation of Heartburn in Nonerosive Reflux Disease (NERD) Patients
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Nortriptyline|DRUG: Placebo arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fat Graft Myringoplasty With and Without Platelet Rich Plasma (PRP) for Treating Smaller Tympanic Membrane Perforations
Status: WITHDRAWN
Conditions: Tympanic Membrane Perforation
Interventions: PROCEDURE: Fat graft with Platelet Rich Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Administration Of Calcium Gluconate for The Reduction of Blood Loss During Elective Cesarean Delivery
Status: RECRUITING
Conditions: Elective Cesarean Delivery
Interventions: DRUG: Calcium Gluconate 10%|DRUG: sodium chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Risk Adapted Beacopp Regimen for Standard and High Risk Hodgkin Lymphoma
Status: COMPLETED
Conditions: Classical Hodgkin Lymphoma|Nodular Sclerosis|Mixed Cellularity|Lymphocyte Depletion|Lymphocyte Rich
Interventions: PROCEDURE: interim therapy scintigraphy study gallium scan or PET/CT|PROCEDURE: "interim gallium or PET/CT"
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Lycopene in Treating Patients Undergoing Radical Prostatectomy for Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Stage I Prostate Cancer|Stage II Prostate Cancer|Stage III Prostate Cancer
Interventions: OTHER: placebo|PROCEDURE: therapeutic conventional surgery|OTHER: laboratory biomarker analysis|DRUG: lycopene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan/Cisplatin With or Without Simvastatin in Chemo-naive Patients With Extensive Disease-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: IP chemotherapy|DRUG: IP chemotherapy plus simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interventions to Promote Well-being of Nightshift Nursing Team Members
Status: COMPLETED
Conditions: Professional Quality of Life
Interventions: BEHAVIORAL: Mindfulness and Sleep Hygiene|BEHAVIORAL: Phyical activity and Sleep Hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PneuMum: Pneumococcal Vaccination of Australian Indigenous Mothers to See if it Protects Their Babies From Ear Disease
Status: UNKNOWN
Conditions: Middle Ear Effusion|Tympanic Membrane Perforation|Acute Otitis Media|Pneumococcal Infections
Interventions: BIOLOGICAL: 23 valent pneumococcal polysaccharide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: FOLFIRI Regimen|DRUG: Sotorasib|DRUG: Panitumumab|DRUG: Bevacizumab-awwb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Carbohydrate Intolerance in Lean and Overweight/Obese Children
Status: COMPLETED
Conditions: Obesity|Type 2 Diabetes
Interventions: DIAGNOSTIC_TEST: Oral Glucose tolerance test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Whey Protein in Type 2 Diabetics
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Whey Protein (WPC) at breakfast|DIETARY_SUPPLEMENT: Other Protein Sources at breakfast|DIETARY_SUPPLEMENT: Low Protein at breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT