pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Long-Term Effect of Soy Consumption on Cardio-Renal Indices and CRP in Type 2diabetes With Nephropathy
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DIETARY_SUPPLEMENT: Soy protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation of Venous Oxygen Saturation Measurements by Non-invasive Mespere Venous Oximeter and Central Venous Catheter
Status: COMPLETED
Conditions: Validation of Oximeter System
Interventions: DEVICE: Mespere Venous Oximeter|DEVICE: Avoximeter 4000
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 2 Study of Inhaled Lipid Cisplatin in Pulmonary Recurrent Osteosarcoma
Status: COMPLETED
Conditions: Pulmonary Relapse of Osteosarcoma
Interventions: DRUG: Inhaled Lipid Cisplatin (ILC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Absorbable Interface Screw Clinical Trial
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Rupture
Interventions: DEVICE: Absorbable interface screws manufactured by Natong Biotechnology|DEVICE: Absorbable interface screws manufactured by INION.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Internet-delivered Cognitive Behavioural Therapy for Adolescents With Anxiety
Status: COMPLETED
Conditions: Anxiety
Interventions: BEHAVIORAL: Guided-ICBT for adolescents with anxiety|BEHAVIORAL: Guided-ICBT with chat|BEHAVIORAL: Guided-ICBT with learning support|BEHAVIORAL: Guided-ICBT with learning support and chat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anlotinib Hydrochloride Combined With EGFR TKIs in Advanced Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-Small-Cell Lung
Interventions: DRUG: Anlotinib Hydrochloride|DRUG: Gefitinib|DRUG: Icotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Digital Heart Rhythm Devices in the Detection of Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DIAGNOSTIC_TEST: Heart rhythm measurements with Preventicus®|DIAGNOSTIC_TEST: Heart rhythm measurements with FibriCheck®|DIAGNOSTIC_TEST: Heart rhythm measurements with Apple Watch®|DIAGNOSTIC_TEST: Heart rhythm measurements with 6L Kardia Mobile®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Laser-aided Csf on the Rate of Leveling and Alignment of Mandibular Anterior Crowding
Status: RECRUITING
Conditions: Orthodontics
Interventions: PROCEDURE: Laser-aided csf|OTHER: placebo laser-aided csf
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clarus Video System and Direct Laryngoscope for Rapid Sequence Induction Intubation With Cricoid Pressure
Status: COMPLETED
Conditions: Intubation, Intratracheal|Laryngoscopes|Anesthesia, General
Interventions: DEVICE: the Clarus Video System as a video stylet|DEVICE: the Clarus Video System as a lightwand|DEVICE: direct laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Cognitive Behavior Therapy in the Treatment of Chronic Pelvic Pain in Women
Status: NOT_YET_RECRUITING
Conditions: Chronic Pelvic Pain Syndrome
Interventions: BEHAVIORAL: Cognitive Behavior Therapy for Chronic Pelvic Pain-CBT-cp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of GSK3845097 in Previously Treated Participants With Advanced Synovial Sarcoma and Myxoid/Round Cell Liposarcoma
Status: TERMINATED
Conditions: Neoplasms
Interventions: DRUG: GSK3845097|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 7 Tesla MRI Study in Patients With Statin Related Muscle Complaints
Status: COMPLETED
Conditions: Statin-related Muscle Pain|Muscle Aches|Muscle Weakness|Muscle Cramp|Muscle Stiffness
Interventions: DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Personalized Antisense Oligonucleotide Therapy for Rare Pediatric Genetic Disease: SCN2A
Status: ACTIVE_NOT_RECRUITING
Conditions: Genetic Disease
Interventions: DRUG: nL-SCN2A-002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Of PF-00572778 And Alprazolam On Naloxone Challenge In Healthy Subjects
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: alprazolam|OTHER: Placebo|DRUG: PF-00572778
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Pharmacokinetic Profile of ETR028 and ETR029 in Healthy Adult Subjects
Status: RECRUITING
Conditions: Acute Pain
Interventions: DRUG: ETR028, ETR029, [ETR028 + ETR029] or HCBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Uninterrupted Clopidogrel Therapy Before Elective Colonoscopy Will Increase the Risk of Post-polypectomy Bleeding
Status: COMPLETED
Conditions: Gastrointestinal Bleeding
Interventions: DRUG: clopidogrel|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of 15 Fraction vs 25 Fraction Pencil Beam Scanning Proton Radiotherapy After Mastectomy in Patients Requiring Regional Nodal Irradiation
Status: COMPLETED
Conditions: Breast Cancer
Interventions: RADIATION: Hypofractionation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Intratechal Levobupivacaine and Adding With Sufetanil and Fentanyl in Ceserean Section
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Levobupivacaine|DRUG: Fentanyl|DRUG: Sufentanil|DRUG: Levobupivacaine|DRUG: Levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arbitration Between Habitual and Goal-directed Behavior in Obsessive-compulsive Disorder: Circuit Dynamics and Effects of Noninvasive Neurostimulation
Status: COMPLETED
Conditions: OCD|Decision-Making|tDCS|fMRI
Interventions: DEVICE: transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Dual-task Obstacle Crossing Training in Ambulatory Subjects With Spinal Cord Injury
Status: UNKNOWN
Conditions: Injuries, Spinal Cord
Interventions: OTHER: Dual-task obstacle crossing training|OTHER: Single-task obstacle crossing training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain From Bunionectomy Compared With Placebo
Status: COMPLETED
Conditions: Hallux Valgus
Interventions: DRUG: Tapentadol IR 50 mg|DRUG: Tapentadol IR 75 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Study of N-Acetylcysteine in Children and Adolescents 5-17 With Bipolar Spectrum Disorders
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Open-label Treatment with N-Acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Dose Escalation Trial of Efavirenz in Solid Tumours or Non-Hodgkin Lymphoma in Therapeutic Failure.
Status: COMPLETED
Conditions: Solid Tumors|Non-Hodgkin's Lymphoma
Interventions: DRUG: Efavirenz 600mg|DRUG: Efavirenz 1200 mg|DRUG: Efavirenz 1800 mg|DRUG: Efavirenz 2200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic, Safety and Efficacy Study of OMS201 in Subjects Undergoing Retrograde Ureteroscopic Removal of Upper Urinary Tract Stones
Status: COMPLETED
Conditions: Urinary Calculi|Urinary Stones|Urinary Tract Stones|Renal Calculi|Kidney Stones
Interventions: DRUG: OMS201|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Silver Alloyed Urinary Catheters and Incidence of Catheter Acquired Urinary Tract Infections (UTI)
Status: COMPLETED
Conditions: Urinary Tract Infection
Interventions: DEVICE: Bactiguard Infection Protection (BIP) Cathter.|DEVICE: Silicone Urinary Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity of Twice-annual Influenza Vaccination in Older Adults in Hong Kong
Status: ACTIVE_NOT_RECRUITING
Conditions: Influenza, Human
Interventions: BIOLOGICAL: Inactivated influenza vaccine (NH formulation)|BIOLOGICAL: Inactivated influenza vaccine (SH formulation)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Photobiomodulation Therapy (PBMT) in Total Hip Arthroplasty
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Hip
Interventions: DEVICE: Portable Pain Away™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Establishing the Safety and Efficacy of Reloxaliase in Patients With Enteric Hyperoxaluria
Status: TERMINATED
Conditions: Enteric Hyperoxaluria
Interventions: DRUG: Reloxaliase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test How Well Different Doses of BI 1569912 Are Tolerated and How Food Influences the Amount of BI 1569912 in the Blood
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: BI 1569912|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Randomized Controlled Study of External Pancreatic Duct Stents in Pancreaticoduodenectomy
Status: RECRUITING
Conditions: Pancreatic Fistula
Interventions: PROCEDURE: External pancreatic duct stent|PROCEDURE: Internal pancreatic duct stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Safety, Tolerability and Pharmacokinetics of RSN0402 in Healthy Volunteers
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis|Lung; Disease, Interstitial, With Fibrosis
Interventions: DRUG: RSN0402 Part 1|DRUG: RSN0402 Part 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect on Obesity of Once Weekly Nimacimab Injection and Once Weekly Nimacimab Injection Co-administered With Semaglutide Injection Versus Placebo
Status: RECRUITING
Conditions: Obesity
Interventions: BIOLOGICAL: Nimacimab injection|BIOLOGICAL: Nimacimab placebo injection|COMBINATION_PRODUCT: semaglutide injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Midostaurin and Gemtuzumab Ozogamicin in First-line Standard Therapy for Acute Myeloid Leukemia (MOSAIC)
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: MODULE: conventional chemotherapy (Cytarabine+Daunorubicin) in combination with midostaurin+GO|DRUG: MAGNOLIA-trial: Midostaurin associated with conventional chemotherapy (AraC+DNR)+GO|DRUG: MAGNOLIA-trial: conventional chemotherapy (AraC+DNR)+GO|DRUG: MAGMA-trial:GO associated with conventional chemotherapy (AraC+DNR)+Midostaurin|DRUG: MAGMA-trial: conventional chemotherapy (AraC+DNR)+Midostaurin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Electrical Stimulation Targeting the Cerebellum for the Treatment of Refractory Temporal Lobe Epilepsy
Status: RECRUITING
Conditions: Transcranial Electrical Stimulation|Temporal Lobe Epilepsy|Magnetic Resonance Imaging|Electroencephalogram
Interventions: DEVICE: Transcranial Alternating Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarker Directed Treatment in Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: FOLFIRI + Cetuximab|DRUG: modifiedFOLFOX6 + Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Pharmacokinetics and Safety of CKD-396
Status: UNKNOWN
Conditions: Type2 Diabetes Mellitus
Interventions: DRUG: CKD-501 and D759|DRUG: CKD-396
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RESULT: Reliable, Emergent Solution Using Liprotamase Treatment
Status: UNKNOWN
Conditions: Exocrine Pancreatic Insufficiency|Cystic Fibrosis
Interventions: DRUG: Liprotamase|DRUG: porcine PERT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Mirvetuximab Soravtansine in Platinum-Resistant, Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Cancer
Interventions: DRUG: Mirvetuximab Soravtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study About Clinical and Pharmacogenetic Safety of Opioid Use for Chronic Pain
Status: SUSPENDED
Conditions: Chronic Pain
Interventions: DRUG: Morphine|DRUG: Oxycodone|DRUG: Fentanyl|DRUG: Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prolonged Exposure Therapy Versus Active Psychotherapy in Treating Post-Traumatic Stress Disorder in Adolescents
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: PROCEDURE: Prolonged Exposure Therapy|PROCEDURE: Active Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Talazoparib and Gemtuzumab Ozogamicin for the Treatment of CD33 Positive Relapsed or Refractory Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Gemtuzumab Ozogamicin|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Talazoparib|DRUG: Talazoparib Tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects Of I-PRF On Gingivectomy and Gingivoplasty
Status: COMPLETED
Conditions: Wound Heal
Interventions: OTHER: İnjectable platelet rich fibrin|PROCEDURE: Gingivectomy anad gingivoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Study of VS-6063 in Patients With KRAS Mutant Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer|Lung Cancer
Interventions: DRUG: defactinib (VS-6063)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Culturally Tailored HPV Psychoeducational Multimedia Intervention
Status: RECRUITING
Conditions: Health Knowledge, Attitudes, Practice|Vaccine-Preventable Diseases|Intention|Adherence, Patient
Interventions: BEHAVIORAL: Culturally Tailored Multimedia Psychoeducational HPV Intervention|BEHAVIORAL: General HPV Multimedia Psychoeducational Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Efficacy of the Masquelet Versus Titanium Mesh Cage Techniques for the Treatment of Large Long Bone Defects
Status: COMPLETED
Conditions: Segmental Long Bone Defects
Interventions: PROCEDURE: Autogenous RIA bone grafting|PROCEDURE: Allogeneic bone grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Educational Intervention to Improve Disease Management Knowledge of Hospitalized Patients With COPD
Status: WITHDRAWN
Conditions: Chronic Obstructive Pulmonary Disease|Patient Education|Inpatients
Interventions: BEHAVIORAL: Inpatient COPD education
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of PACAP38/VIP on Migraineurs Measured by Magnetic Resonance
Status: COMPLETED
Conditions: Migraine Without Aura
Interventions: DRUG: Pituitary Adenylate Cyclase-Activating Polypeptide-38|DRUG: Vasoactive Intestinal Peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Emulsion Droplet Physical State on Postprandial Lipemia and Satiety
Status: COMPLETED
Conditions: Postprandial Lipemia|Satiety
Interventions: OTHER: Emulsion with solid droplets|OTHER: Emulsion with liquid droplets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Endoscopic Ultrasound-guided Radiofrequency Ablation in Primary Aldosteronism
Status: RECRUITING
Conditions: Primary Aldosteronism|Aldosterone-Producing Adenoma|Hypercortisolism
Interventions: PROCEDURE: EUS-RFA of left adrenal tumour in PA with AVS-verified left lateralisation|PROCEDURE: EUS-RFA of left adrenal tumour in PA, "debulking group"|PROCEDURE: EUS-RFA of left adrenal tumour in MACS with AVS-verified left lateralisation|PROCEDURE: EUS-RFA of left adrenal tumour in MACS with bilateral overproduction, "debulking group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Cabozantinib Efficacy, Safety and Tolerability in Metastatic Renal Carcinoma in Aged Fragile Patients: CABOMAYOR Study
Status: COMPLETED
Conditions: Old Age; Debility|Renal Carcinoma Metastatic
Interventions: DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine How and Why HIV-Infected Subjects on Anti-viral Treatment Develop Lipodystrophy
Status: COMPLETED
Conditions: HIV Infections|Lipodystrophy
Interventions: DRUG: Nelfinavir mesylate|DRUG: Stavudine|DRUG: Lamivudine|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Gemcitabine/Carboplatin First-line Chemotherapy +/- Apatorsen in Advanced Squamous Cell Lung Cancers
Status: UNKNOWN
Conditions: Squamous Cell Lung Cancer
Interventions: DRUG: Apatorsen (OGX-427)|DRUG: Gemcitabine|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study of Adherence to LABA / LAMA in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium 2x2.5µg tiotropium (equivalent to 2x3.154µg tiotropium bromide monohydrate) Respimat® inhaler and cartridge Solution for inhalation|DRUG: Indacterol 300 µg|DRUG: Tiotropium 18µg (equivalent to 22.5µg tiotropium bromide monohydrate) HandiHaler® device Inhalation powder, hard capsule|DRUG: Indacterol 150 µg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect on Gait Pattern During Robot Assisted Gait Training (RAGT) of End-effector Type in Burn Patients
Status: RECRUITING
Conditions: Burns|Gait Training|Rehabilitation
Interventions: OTHER: robot assisted gait training|OTHER: conventional gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychoeducational Intervention for Patients With Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma|Cirrhosis
Interventions: BEHAVIORAL: HARMONY|OTHER: Enhanced usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Renal Impact of KAFTRIO in Mucoviscidose Population
Status: RECRUITING
Conditions: Cystic Fibrosis
Interventions: BIOLOGICAL: Evaluation of the parameters of the lithiasis assessment before and after KAFTRIO initiation|DRUG: Collection of Arterial pressure, metabolic data, kidney function, proteinuria and hematuria before and after KATRIO initiation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Oral Pregabalin on Spinal Neurotransmitters in Patients Undergoing Knee Replacement
Status: COMPLETED
Conditions: PAIN
Interventions: DRUG: Pregabalin|DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Alpha-lipoic Acid Reduces Left Ventricular Mass in Normotensive Type 2 Diabetic Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Type 2 Diabetes|Coronary Artery Disease|Left Ventricular Mass
Interventions: DRUG: alpha-lipoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Modafinil Treatment for Cocaine Dependence and HIV High-Risk Behavior
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: Modafinil|DRUG: placebo|BEHAVIORAL: Cognitive Behavioral Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Do Therapy Dogs Improve Behavior and Reduce Anxiety in Pediatric Dental Patients?
Status: ENROLLING_BY_INVITATION
Conditions: Therapy Animals|Dental Anxiety|Child Behavior|Anesthesia, Local
Interventions: BEHAVIORAL: Therapy Dog
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Lumbar Stabilization Exercises and Circular Dances in Chronic Non Specific Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Lumbar Stabilization Exercise|OTHER: Circular dance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Program on Surgical Control of Hyperlipidemias (POSCH)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Myocardial Infarction|Myocardial Ischemia
Interventions: PROCEDURE: jejunoileal bypass|BEHAVIORAL: diet, fat-restricted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Positive Pressure at Induction of Anesthesia in Children
Status: COMPLETED
Conditions: Continuous Positive Airway Pressure|Hypoxia|General Anesthesia
Interventions: DEVICE: Continuous Positive Airway Pressure|DEVICE: Open system ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: EGFRBi-Armed Autologous T Cells in Treating Patients With Recurrent or Refractory Glioblastoma
Status: WITHDRAWN
Conditions: Adult Brain Glioblastoma|Adult Gliosarcoma|Recurrent Brain Neoplasm
Interventions: BIOLOGICAL: EGFRBi-Armed Autologous T Cells|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Diet and Exercise for Improving Knee Osteoarthritis in Obese and Overweight Older Adults
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: BEHAVIORAL: Diet|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fiber Tolerability in Children Aged 3-7 Year
Status: COMPLETED
Conditions: Signs and Symptoms, Digestive
Interventions: DRUG: Placebo (including Maltodextrin)|DRUG: Dose 1 - Promitor®|DRUG: Dose 2 - Promitor®|DRUG: Dose 3 - Promitor®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effect of Probiotics (Bio-Three) in Children's Enterocolitis
Status: COMPLETED
Conditions: Diarrhea|Enteritis|Enterocolitis
Interventions: DRUG: Biothree
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Music for Sleep After Stroke
Status: RECRUITING
Conditions: Stroke|Cardiovascular Diseases|Brain Diseases|Vascular Diseases|Insomnia|Sleep Disorder|Sleep Disturbance
Interventions: BEHAVIORAL: Mindful music-listening with sleep hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Care Provided Through Skin Care Protocol on Elderly Patients
Status: RECRUITING
Conditions: Elderly Person|Comfort|Quality of Life|Skin Moisture|Skin
Interventions: OTHER: pre-post test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ampicillin / Sulbactam vs. Ampicillin / Gentamicin for Treatment of Chorioamnionitis
Status: COMPLETED
Conditions: Chorioamnionitis
Interventions: DRUG: Unasyn|DRUG: Ampicillin/gentamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Corn and Heart Health Study
Status: COMPLETED
Conditions: Gut Microbiome|Cholesterol, LDL|Cholesterol, HDL
Interventions: OTHER: Refined cornmeal flour|OTHER: 50/50 refined cornmeal-bran mix|OTHER: Whole grain cornmeal flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Phase 1b Study of SGN-75 in Combination With Everolimus in Patients With Renal Cell Carcinoma
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: SGN-75|DRUG: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy Study Evaluating the Combination of Bevasiranib & Lucentis Therapy in Wet AMD
Status: TERMINATED
Conditions: Macular Degeneration
Interventions: DRUG: bevasiranib|DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Detection and Early Action for HPV-positive Oropharynx Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: HPV Positive Oropharyngeal Squamous Cell Carcinoma
Interventions: DIAGNOSTIC_TEST: Blood test for HPV DNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Go Fish: Omega-3 Fatty Acid Supplementation in Diabetes-Related Kidney Disease
Status: COMPLETED
Conditions: Diabetes
Interventions: DIETARY_SUPPLEMENT: Lovaza (fish oil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Clinical Utility of the Oxford Virtual Autism Assessment Tool (OVAAT)
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Healthy|Neurotypical
Interventions: DIAGNOSTIC_TEST: Oxford Virtual Autism Assessment Tool (OVAAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Vancomycin and Tobramycin Powder Use in Acute Open Fractures
Status: ENROLLING_BY_INVITATION
Conditions: Infections
Interventions: DRUG: Cephalosporin or clindamycin/vancomycin antibiotics..|DRUG: Vancomycin and Tobramycin antibiotics.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Innovative Training Methods for Frail Elderly in the Training Gain Stage
Status: COMPLETED
Conditions: Poor Performance Status
Interventions: DEVICE: Stochastic resonance whole-body vibration|DEVICE: Exergame|DEVICE: Leg press
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calcium Administration in Cardiac Surgery
Status: UNKNOWN
Conditions: Cardiac Surgery|Cardiopulmonary Bypass
Interventions: DRUG: Calcium Chloride|DRUG: 0.9% Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Electrocardiogram Waveforms Produced Through the Utilization of the Sherlock 3CG™ Tip Confirmation System
Status: COMPLETED
Conditions: Indication for Peripheral Intravenous Catheterization
Interventions: DEVICE: SHERLOCK 3CG™ Tip Confirmation System with MODUS Software
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Polyethylene Glycol Loxenatide Pharmacokinetics Study in Subjects With Normal and Insufficiency Renal Function
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: PEX168
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Lidocaine on the Cervix and Intra-Cervical Prior to Insertion of Intrauterine Devices
Status: UNKNOWN
Conditions: Contraception
Interventions: DRUG: Lidocaine|DRUG: Lubricant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Supporting Safe Use of Medications by Parents After Infant Discharge From the Neonatal Intensive Care Unit
Status: RECRUITING
Conditions: Medication Administered in Error
Interventions: OTHER: HELPix|OTHER: HELPix+Tech
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Peer-education Programs for Adolescents Diagnosed With Asthma
Status: RECRUITING
Conditions: Asthma|Self Esteem|Adolescent Behavior
Interventions: OTHER: Technology Based Asthma Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of RC48-ADC Administered Intravenously to Subjects With HER2-Positive in Advanced Malignant Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: RC48-ADC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Immunogenicity of Two Vaccination Schedules of an Inactivated Vaccine Against COVID-19 in Adults
Status: COMPLETED
Conditions: Covid19|Vaccines
Interventions: BIOLOGICAL: SARS-CoV-2 inactivated vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of BCG on Immune Response
Status: COMPLETED
Conditions: Sepsis
Interventions: BIOLOGICAL: BCG vaccine|BIOLOGICAL: Lipopolysaccharide (LPS) E. Coli 1 ng/kg intravenously
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Manual Therapy in Addition to Pulmonary Rehabilitation in Moderate Chronic Obstructive Pulmonary Disease.
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease Moderate
Interventions: OTHER: Manual Therapy Plus Pulmonary Rehabilitation|OTHER: Sham Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Integrated CKD Care Program in Early Diabetic Nephropathy in Primary Health Care Setting.
Status: COMPLETED
Conditions: Chronic Kidney Disease|Diabetic Nephropathy
Interventions: BEHAVIORAL: Community-based Integrated CKD Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of BMS-863233 in Patients With Hematologic Cancer
Status: TERMINATED
Conditions: Refractory Hematologic Cancer
Interventions: DRUG: Cdc7-inhibitor (BMS-863233)|DRUG: Cdc7-inhibitor (BMS-863233)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Extraperitoneal and Intraperitoneal Cesarean Technique
Status: COMPLETED
Conditions: Postpartum Fever|Ileus|Hemorrhage|Pain
Interventions: PROCEDURE: Extraperitoneal cesarean section|PROCEDURE: Intraperitoneal cesarean section
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Role of Lung Ultrasound In Assessment Of Recruitment Maneuvers In Ventilated Preterms With Respiratory Distress Syndrome and Its Correlation With Tracheal IL-6 Level
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Newborn
Interventions: OTHER: lung recruitment maneuver|OTHER: tracheal IL-6 level|OTHER: US guided lung recruitment maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Efficacy and Safety of 3D Printing for Orbital Surgery.
Status: RECRUITING
Conditions: Thyroid Associated Ophthalmopathy|Surgical Procedure, Unspecified
Interventions: DEVICE: 3D printing model/guide.|PROCEDURE: Standard surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Saxagliptin add-on Compared to Uptitration of Metformin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Saxagliptin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Mobile Augmented Reality (MAR) on Oral Healthcare Education for the Independent Elderly
Status: COMPLETED
Conditions: Aged
Interventions: OTHER: Mobile Augmented Reality (MAR) for oral health education program|OTHER: Lecture-based oral health education program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dry Needling on the Treatment of Chronic Somatosensory Tinnitus: An Open Pilot Study
Status: UNKNOWN
Conditions: Tinnitus|Trigger Point Pain, Myofascial|Somatosensory Disorders
Interventions: PROCEDURE: Dry Needing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Gefapixant (MK-7264/AF-219) on Cough Reflex Sensitivity in Healthy and Chronic Cough Participants (MK-7264-014)
Status: COMPLETED
Conditions: Refractory Chronic Cough
Interventions: DRUG: Gefapixant 100 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paravertebral Analgesia Associated With Intravenous Morphine PCA After Thoracotomy
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: ropivacaine|OTHER: nacl 0,9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Wire-in-needle vs. Traditional Technique for Ultrasound-guided Central Venous Catheter Placement
Status: COMPLETED
Conditions: Central Venous Catheter Placement
Interventions: PROCEDURE: Ultrasound-guided wire-in-needle technique for central venous catheter placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: VEGF Trap in Treating Patients With Recurrent Malignant Gliomas That Did Not Respond to Temozolomide
Status: COMPLETED
Conditions: Adult Anaplastic Astrocytoma|Adult Anaplastic Oligodendroglioma|Adult Giant Cell Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Tumor
Interventions: BIOLOGICAL: ziv-aflibercept|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone-Eluting Cochlear Implant Electrode
Status: COMPLETED
Conditions: Hearing Loss, Sensorineural|Sensorineural Hearing Loss
Interventions: DEVICE: CIDEXEL implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: SPI-1005 for the Treatment of Patients With Meniere's Disease
Status: COMPLETED
Conditions: Meniere's Disease
Interventions: DRUG: 200mg SPI-1005 BID|DRUG: 400mg SPI-1005 BID|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Assessment of the Effectiveness and Safety of Herpes Patch SOS in the Treatment of Herpes Simplex Labialis in Comparison to a Competitor's Product.
Status: COMPLETED
Conditions: Herpes Simplex Labialis
Interventions: OTHER: Herpes Patch SOS (Hansaplast®)|OTHER: Herpes vesicle patch of Compeed®
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Study to Compare How the Body Absorbs, Distributes and Excretes the Drug Selitrectinib (BAY2731954) Given as Two Different Tablet Formulations or as Liquid Formulations Including the Effect of Food on the Absorption, Distribution or Excretion of the Different Formulations in Healthy Participants
Status: COMPLETED
Conditions: Solid Tumors Harboring NTRK Fusion
Interventions: DRUG: Selitrectinib (BAY2731954) Adult tablet|DRUG: Selitrectinib (BAY2731954) Pediatric tablet|DRUG: Selitrectinib (BAY2731954) Oral solution|DRUG: Selitrectinib (BAY2731954) Oral suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prospective Study of Minimally Invasive Lapidus Procedure for Hallux Valgus Deformities
Status: NOT_YET_RECRUITING
Conditions: Hallux Valgus and Bunion
Interventions: PROCEDURE: Minimally invasive lapidus procedure with no arthroscopy|PROCEDURE: Minimally invasive lapidus procedure with arthroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PEG Interferon Alpha 2B and Low-Dose Ara-C in Early Chronic Phase CML
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Peg Interferon Alpha 2b (Peg Intron)|DRUG: Ara-C (cytosine arabinoside)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Super-boosted Lopinavir/Ritonavir Given With Rifampin
Status: TERMINATED
Conditions: AIDS|Tuberculosis
Interventions: DRUG: Lopinavir/ritonavir and ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EVALUATION OF AMIFOSTINE FOR MUCOSAL AND HEMOPOETIC PROTECTION AND CARBOPLATIN, TAXOL, RADIOTHERAPY IN THE MANAGEMENT OF PATIENTS WITH HEAD AND NECK CANCER.(GCC 0202)
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Amifostine|DRUG: Carboplatin|DRUG: Taxol|DEVICE: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First Line Chemotherapy for Classical Hodgkin Lymphoma in Russia (HL-Russia-1)
Status: RECRUITING
Conditions: Hodgkin Lymphoma, Adult
Interventions: DRUG: Doxorubicin|DRUG: Bleomycin|DRUG: Vinblastine|DRUG: Dacarbazine|DRUG: Etoposide|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Vincristine|DRUG: Dexamethasone|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tipifarnib and Osimertinib in EGFR-mutated Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: NSCLC
Interventions: DRUG: Tipifarnib|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emotional Regulation in Children With ND: the Role of Genomic Variation, Proteomic Patterns, and Early Experience
Status: RECRUITING
Conditions: Neurodevelopmental Disabilities|Emotional Regulation|Epigenetics|Parental Factors
Interventions: DIAGNOSTIC_TEST: DNA methylation analysis|DIAGNOSTIC_TEST: Proteomics analysis|DIAGNOSTIC_TEST: Still Face Paradigm
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Kinesiotaping Combined With Therapeutic Exercise in Upper Extremity Spasticity and Function in Subacute Stroke Patients
Status: COMPLETED
Conditions: Stroke|Upper Extremity Spasticity
Interventions: OTHER: Kinesiotaping|OTHER: stretching exercise|OTHER: OT rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Drug-Drug Interaction Study of the Effect of Rabeprazole, Itraconazole or Fluconazole on the Pharmacokinetics of Vismodegib
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: fluconazole|DRUG: itraconazole|DRUG: rabeprazole|DRUG: vismodegib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Trial of Decongestive Lymphatic Therapy for Lymphedema in Women With Breast Cancer "DELTA STUDY"
Status: COMPLETED
Conditions: Breast Cancer|Lymphedema
Interventions: PROCEDURE: Lymphatic Massage (Decongestive Lymphatic Therapy) (Arm 1)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Multiple Immunotherapy-Based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-Pancreatic Cancer)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Nab-Paclitaxel|DRUG: Gemcitabine|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: Fluorouracil|DRUG: Atezolizumab|DRUG: Cobimetinib|DRUG: PEGPH20|DRUG: BL-8040|DRUG: Selicrelumab|DRUG: Bevacizumab|DRUG: RO6874281|DRUG: AB928|DRUG: Tiragolumab|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Daily vs Intermittent Regimen of ATT in HIV With Pulmonary Tuberculosis
Status: COMPLETED
Conditions: HIV Infection|Pulmonary TB
Interventions: DRUG: ATT (Ethambutol, Pyrazinamide, INH, Rifampicin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT