pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Autologous Transplantation of Bone Marrow Mononuclear Stem-Cells by Mini-Thoracotomy
Status: COMPLETED
Conditions: Dilated Cardiomyopathy
Interventions: PROCEDURE: intramyocardial bone marrow stem cells implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Double Target Therapy Combined With Chemotherapy in First-line Treatment of HER2+ Breast Cancer, MA-BC-II-038
Status: RECRUITING
Conditions: HER2-positive Breast Cancer
Interventions: DRUG: Pyrotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Sitagliptin/Metformin Combination Tablet (MK0431A-122)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Co-administration of 50 mg sitagliptin and 500 mg metformin|DRUG: sitagliptin/metformin 50 mg/500 mg tablet|DRUG: Co-administration of 50 mg sitagliptin and 850 mg metformin|DRUG: sitagliptin/metformin 50 mg/850 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AZD2066 Neuropathic Pain - Mechanical Hypersensitivity
Status: TERMINATED
Conditions: Neuropathic Pain|Mechanical Hypersensitivity
Interventions: DRUG: AZD2066|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "SALT-2 Trial" Study of Ascending Levels of Tolvaptan in Hyponatremia
Status: COMPLETED
Conditions: Hyponatremia|Water Intoxication|Inappropriate ADH Syndrome|Water-electrolyte Imbalance
Interventions: DRUG: Tolvaptan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety of a Single Escalating Dose of ACRX-100 in Adults With Ischemic Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: BIOLOGICAL: ACRX-100
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and Bryostatin 1 in Treating Patients With Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Acinar Cell Adenocarcinoma of the Pancreas|Duct Cell Adenocarcinoma of the Pancreas|Recurrent Pancreatic Cancer|Stage III Pancreatic Cancer|Stage IV Pancreatic Cancer
Interventions: DRUG: paclitaxel|DRUG: bryostatin 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine, Oxaliplatin, and Bevacizumab in Treating Patients With Metastatic or Recurrent Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: oxaliplatin|DRUG: Capecitabine|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ambulatory Blood Pressure Reduction After Rosiglitazone Treatment In Normotensive Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: rosiglitazone(drug), blood pressure lowering effect
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glycemic Control to Prevent Cardiac Morbidity in Vascular Surgery
Status: TERMINATED
Conditions: Peripheral Vascular Disease|Abdominal Aortic Aneurysm
Interventions: DRUG: continuous intravenous insulin infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed Disodium and Cisplatin Followed by Surgery With or Without Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Malignant Mesothelioma
Interventions: DRUG: Cisplatin|DRUG: Pemetrexed|PROCEDURE: Therapeutic conventional surgery|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 14-Day Cumulative Irritation Patch Test in Subjects With Normal Skin
Status: COMPLETED
Conditions: Cumulative Irritation
Interventions: DEVICE: Novel lubricant Miami w/ fragrance|DEVICE: Novel lubricant Miami no fragrance|DEVICE: KY Liquid lubricant|DEVICE: Astroglide Gel lubricant|DEVICE: Wet Platinum lubricant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Pollen Challenges on Dermal Symptoms in Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: OTHER: Grass pollen : Dactylis glomerata|OTHER: Challenge with clean air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Methodological Study To Evaluate The Effects of Single Oral Doses Of Pioglitazone 45 mg And Rosiglitazone 8 mg On Sodium Balance In Healthy Male Volunteers
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: pioglitazone/rosiglitazone/placebo|DRUG: rosiglitazone/pioglitazone/placebo|DRUG: placebo/pioglitazone/rosiglitazone|DRUG: pioglitazone/placebo/rosiglitazone|DRUG: rosiglitazone/placebo/pioglitazone|DRUG: placebo/rosiglitazone/pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Effectiveness of Ultrasound (US) Guided Supraclavicular Block
Status: WITHDRAWN
Conditions: Analgesia|Pain
Interventions: DRUG: 20 ml of ropivacaine 0.5%|DRUG: 30 ml of ropivacaine 0.5%|DRUG: 40 ml of ropivacaine 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Omega-3 Fatty Acids on Metabolic Syndrome
Status: UNKNOWN
Conditions: Metabolic Syndrome X
Interventions: DIETARY_SUPPLEMENT: Omega-3 fatty acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adapted Lifestyle-integrated Functional Exercise Program for Medically Underserved Older Adults
Status: COMPLETED
Conditions: Accidental Fall
Interventions: BEHAVIORAL: Adapted LiFE|BEHAVIORAL: Attention control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Web-based Support for Family Caregivers of Patients With Advanced Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Family|End of Life|Cancer Metastatic|Chronic Illness
Interventions: OTHER: Narstaende.se
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Post-operative Analgesia Efficacy Using Ultrasound-guided Transmuscular Quadratus Lumborum Block Versus Ultrasound-guided Quadratus Lumborum Type II Block.
Status: UNKNOWN
Conditions: Nerve Block
Interventions: DRUG: Bupivacaine|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: F16IL2 in Combination With Nivolumab in Patients With Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: F16IL2|DRUG: Nivolumab, fixed dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Gas Propagation in Snow During Breathing of Subjects Under Simulated Avalanche Snow
Status: ENROLLING_BY_INVITATION
Conditions: Accident Caused by Snow Avalanche
Interventions: OTHER: extreme hypercapnia induced by ventilation insufficiency
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral Contraceptive and Cardiovascular Risk in PCOS
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: BEHAVIORAL: Physical exercise|DRUG: OC - Drospirenone plus Ethynylestradiol|DIETARY_SUPPLEMENT: Vitamin, polyvitamins tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 177Lu-PSMA-617 and Pembrolizumab in Treating Patients With Metastatic Castration-Resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Castration Levels of Testosterone|Castration-Resistant Prostate Carcinoma|Metastatic Prostate Carcinoma|Prostate Adenocarcinoma|Stage IV Prostate Cancer|Stage IVA Prostate Cancer|Stage IVB Prostate Cancer
Interventions: DRUG: Lutetium Lu 177-PSMA-617|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Electro-acupuncture for Mild-to-moderate Perimenopausal Depression
Status: UNKNOWN
Conditions: Perimenopause|Depression
Interventions: DEVICE: electro-acupuncture|DRUG: escitalopram oxalate tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect Of Stretching Programme On Shoulder Performance In Volleyball Players With Posterior Shoulder Tightness
Status: COMPLETED
Conditions: Posterior Shoulder Tightness
Interventions: OTHER: Stretching exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Duloxetine and Dexamethasone for Improving Postoperative Pain
Status: COMPLETED
Conditions: Post Operative Pain Control
Interventions: DRUG: Dulox capsule (60mg)|DRUG: combined Dulox capsule (60 mg) orally and Dex 0.1mg/kg diluted in 100 ml 0.9% NS IVI|DRUG: a placebo capsule identical to Dulox capsule and 100 ml 0.9% NS IVI over 15 min, as a placebo for dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety and Pharmacokinetic Study of NBM-BMX Administered Orally to Patients With Advanced Cancer
Status: COMPLETED
Conditions: Malignant Neoplasm
Interventions: DRUG: NBM-BMX softgel capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: US-Guided Serratus Anterior Plane Block Versus Thoracic Epidural in Patients Undergoing Thoracotomy
Status: COMPLETED
Conditions: Lung Cancer|Acute Pain|Chronic Pain
Interventions: PROCEDURE: Continuous Serratus anterior plane block|PROCEDURE: Thoracic Epidural|DRUG: Bupivacaine|DRUG: lidocaine with epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Pazopanib With Low Fat Meal (PALM) in Advanced Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Pazopanib|OTHER: Low Fat Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tumor Associated Antigen Specific T Cells (TAA-T) With PD1 Inhibitor for Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Hodgkin Lymphoma|Diffuse Large B Cell Lymphoma
Interventions: BIOLOGICAL: TAA-T cells|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study on the Safety and Efficacy of Robot-assisted Pancreaticoduodenectomy
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer|Common Bile Duct Diseases|Periampullary Carcinoma
Interventions: PROCEDURE: Robot-assisted Pancreaticoduodenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAPS2 Transfusion Antenatally in Pregnant Women With SCD
Status: UNKNOWN
Conditions: Sickle Cell Disease|Pregnancy, High Risk|Blood Transfusion Complication
Interventions: BIOLOGICAL: Serial prophylactic exchange blood transfusion (SPEBT).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture Effect on Digestion in Critically Ill Post-Operative Oral and Hypo-pharyngeal Cancer Patients
Status: COMPLETED
Conditions: Oral Cancer|Hypopharyngeal Cancer
Interventions: OTHER: Specific acupuncture group|DRUG: Metoclopramide 10mg|OTHER: Non-specific acupuncture group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Evaluating ITI-007 (Lumateperone) as a Monotherapy for the Treatment of Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Depression
Interventions: DRUG: ITI-007 (Lumateperone)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Ballet-inspired Low-impact At-home Workout Programme for Adults With Stroke
Status: COMPLETED
Conditions: Stroke|Gait, Unsteady|Balance; Distorted|Memory Impairment
Interventions: BEHAVIORAL: Ballet-inspired workouts|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Assessment of Prednisone In Remission Trial - Centers of Excellence Approach
Status: ACTIVE_NOT_RECRUITING
Conditions: Granulomatosis With Polyangiitis
Interventions: DRUG: 5 mg Prednisone|DRUG: 0 mg Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of SHP465 in Children Aged 4 to 12 Years Diagnosed With Attention-deficit/Hyperactivity Disorder (ADHD)
Status: TERMINATED
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: DRUG: SHP465
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Clavamox, Film-coated Tablets, 875 mg + 125 mg Pharmtechnology LLC, Belarus), and Augmentin®, Film-coated Tablets, 875 mg + 125 mg (GlaxoSmithKline Trading CJSC, Russia), in Healthy Volunteers Under Fasting Conditions
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Clavamox|DRUG: Augmentin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
Status: RECRUITING
Conditions: Advanced Solid Malignancies
Interventions: DRUG: AZD9574|DRUG: Temozolomide|DRUG: [11C]AZ1419 3391|DRUG: Datopotamab Deruxtecan (Dato-DXd)|DRUG: Trastuzumab Deruxtecan (T-DXd)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adverse Health Effects of Mainstream and Secondhand Hookah Smoke in NYC Hookah Bars
Status: COMPLETED
Conditions: COPD
Interventions: OTHER: Active smoking of Tobacco Hookah for 2 hours|OTHER: Exposure to tobacco hookah second hand smoke|OTHER: Visit a win bar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Open-Label Study Of Lamictal In Neurotic Excoriation
Status: COMPLETED
Conditions: Neurotic Disorders|Obsessive-Compulsive Disorder
Interventions: DRUG: Lamictal (lamotrigine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Dalpiciclib With Endocrine Therapy as Adjuvant Treatment in HR+/ HER2- Early Breast Cancer
Status: RECRUITING
Conditions: Early Breast Cancer
Interventions: DRUG: Dalpiciclib|DRUG: Endocrine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pleiotropy and Mechanism of Peripheral Nerve Related Genes in the Progression of Amyotrophic Lateral Sclerosis
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DIAGNOSTIC_TEST: Patient information collection, exon sequencing and follow-up.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Efficacy and Safety Study of Corifollitropin Alfa (MK-8962) in Contrast to Recombinant FSH for Use in Controlled Ovarian Stimulation of Indian Women (P07056, Also Known as MK-8962-029)
Status: WITHDRAWN
Conditions: Infertility
Interventions: DRUG: MK-8962|DRUG: recFSH|DRUG: Ganirelix|DRUG: human Chorionic Gonadotropin (hCG)|DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rivaroxaban Once Daily Versus Dose-adjusted Vitamin K Antagonist on the Biomarkers in Acute Decompensated Heart Failure and Atrial Fibrillation (ROAD HF-AF)
Status: UNKNOWN
Conditions: Acute Heart Failure
Interventions: DRUG: Rivaroxaban|DRUG: Warfarin + LMWH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PCM1-JAK2 in Therapy Related Neoplasms
Status: UNKNOWN
Conditions: Detection of PCM1-JAK2 Fusion Gene by FISH in the Two Types of t-MDS/AML and Relationship Between PCM1-JAK2 Fusion Gene and Cumulative Dose, Dose Intensity
Interventions: OTHER: fresh samples are obtained from patients for detction of PCM1- JAK2 fusion gene
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Low-Level Laser Therapy on Stability During Retention Phase.
Status: RECRUITING
Conditions: Orthodontic Retainers|Laser Therapy
Interventions: RADIATION: Ga-Al-As diode laser (Ilase, USA)|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Performance Analysis of the Exair(TM) Prolapse Repair System in the Treatment of Pelvic Organ Prolapse
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: DEVICE: Exair Transvaginal Mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbreaks in the OR to Mitigate High Physical and Mental Demands
Status: COMPLETED
Conditions: Attention Concentration Difficulty|Neck Pain|Back Pain|Shoulder Pain|Fatigue
Interventions: OTHER: Micro Break with Dynamic Exercise Activities
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Observational Study of Xeloda (Capecitabine) in Patients With Metastatic Colorectal Cancer, Colon Cancer in the Adjuvant Setting, Advanced Gastric Cancer or Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer, Colorectal Cancer, Gastric Cancer
Interventions: DRUG: Capecitabine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Periapical Healing After One or Two-visits to Endodontic Treatment in Adolescents Patients
Status: COMPLETED
Conditions: Periapical Periodontitis
Interventions: PROCEDURE: Root canal therapy in one visit|PROCEDURE: Root Canal Therapy in two-vist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Letermovir in Preventing Cytomegalovirus (CMV) Infection in Lung Transplant Recipients vs. Valganciclovir.
Status: NOT_YET_RECRUITING
Conditions: Infections, Cytomegalovirus
Interventions: DRUG: Letermovir 240 mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab (MK-3475) Versus Placebo After Complete Resection of High-Risk Stage III Melanoma (MK-3475-054/1325-MG/KEYNOTE-054)
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: BIOLOGICAL: pembrolizumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ferumoxytol for Iron-Deficiency Anemia in Chronic Kidney Disease and Peritoneal Dialysis Patients
Status: COMPLETED
Conditions: Iron-Deficiency Anemia|Inflammation|Oxidative Stress
Interventions: DRUG: Ferumoxytol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant ADT With TULSA in the Treatment of Intermediate Risk Prostate Cancer
Status: RECRUITING
Conditions: Localized Prostate Carcinoma|Castration-Naive Prostate Cancer|Intermediate Risk Prostate Cancer|Prostate Cancer
Interventions: DRUG: Degarelix|DEVICE: MRI-guided transurethral ultrasound ablation (TULSA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Plasmalyte A, Normal Saline and Ringer Lactate as Intraoperative Fluid During Renal Transplantation
Status: UNKNOWN
Conditions: Acid-Base Balance Disorder
Interventions: DRUG: intravenous fluid administration WITH NORMAL SALINE, PLASMALYTE A, OR RINGER LACTATE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Urinary Bladder Hypertrophy on Urge Urine Incontinence After Radical Prostatectomy
Status: UNKNOWN
Conditions: Prostate Cancer|Urinary Incontinence, Urge|Incontinence|Prostatectomy|Overactive Bladder
Interventions: PROCEDURE: Radical prostatectomy|DIAGNOSTIC_TEST: Initial evaluation|DIAGNOSTIC_TEST: Evaluation after 1,3,6,9,12 months
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Allergen Challenge on Inflammation Induced by Toll-like Receptor Stimulation in a Nasal Model
Status: UNKNOWN
Conditions: Asthma
Interventions: OTHER: Nasal allergen challenge|OTHER: Nasal placebo challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Melflufen (Melphalan Flufenamide) in Combination With Daratumumab in Relapsed-Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Relapsed Multiple Myeloma|Relapsed-Refractory Multiple Myeloma
Interventions: DRUG: Melflufen|DRUG: Dexamethasone|DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Surveillance of VaxigripTetra® and Efluelda® Influenza Vaccines in Europe During the Influenza Season 2021/22
Status: COMPLETED
Conditions: Influenza (Healthy Volunteers)
Interventions: BIOLOGICAL: Quadrivalent Influenza Vaccine|BIOLOGICAL: High-Dose Quadrivalent Influenza Vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Smartphone Application for Initiation of Protective Ventilation. Clinical Impact of Instrumental Dead Space Reduction
Status: RECRUITING
Conditions: ARDS, Human|Mechanical Ventilation Complication|Humidifier Lung
Interventions: PROCEDURE: Protective ventilation implementation|PROCEDURE: Protective ventilation with HME|PROCEDURE: Protective ventilation with Heated humidifier|PROCEDURE: Tidal Volume reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical and Biological Digestive Peritoneal Carcinomatosis Data Base From the French National Network of Peritoneal Surface Malignancies
Status: COMPLETED
Conditions: Digestive Peritoneal Carcinomatosis
Interventions: OTHER: Collection of biospecimens and Quality of Life (QoL) assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Terazosin for Dementia With Lewy Bodies
Status: NOT_YET_RECRUITING
Conditions: Dementia With Lewy Bodies
Interventions: DRUG: Terazosin Hydrochloride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Transcutaneous Electrical Nerve Stimulation in Diabetic Neuropathy
Status: TERMINATED
Conditions: Diabetic Neuropathy Peripheral
Interventions: DEVICE: Transcutaneous electrical neurostimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Exploration of Parameters of Transcranial Direct Current Stimulation (tDCS) in Chronic Pain
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DEVICE: High Definition Transcranial Direct Current Stimulation (HD-tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Study of the Factors Favoring the Transition From Prediabetes to Diabetes on Reunion Island.
Status: RECRUITING
Conditions: Diabetes
Interventions: OTHER: prevention program for prediabetes "Say No to Diabetes"
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer
Status: RECRUITING
Conditions: Advanced Lung Non-Squamous Non-Small Cell Carcinoma|Metastatic Lung Non-Squamous Non-Small Cell Carcinoma|Recurrent Lung Non-Squamous Non-Small Cell Carcinoma|Stage IIIB Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8
Interventions: BIOLOGICAL: Bevacizumab|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Multigated Acquisition Scan|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TESE and Non Obstructive Azoospermia
Status: UNKNOWN
Conditions: Azoospermia, Nonobstructive
Interventions: PROCEDURE: Conventional TESE|PROCEDURE: Microdissection TESE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Optimal Duration of Dual Antiplatelet Therapy After Implantation of Endeavor Stent
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Aspirin, Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Stabilization Exercises in Individuals With Non-Specific Chronic Neck Pain.
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Telerehabilitation-based cervical and scapular stabilization exercises|OTHER: Telerehabilitation-based cervical and core stabilization exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Hematopoietic and Lymphoid System Neoplasm|Myelodysplastic Syndrome|Myeloproliferative Neoplasm|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Azacitidine|DRUG: Ivosidenib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Mindfulness Enhance BMI in Obese Adolescents Enrolled in the Bright Bodies Weight Management Program?
Status: COMPLETED
Conditions: Pediatric Obesity
Interventions: BEHAVIORAL: Traditional Healthy Lifestyle Program|BEHAVIORAL: Mindfulness Meditation Instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HPV Multilevel Intervention Strategies Targeting Immunization in Community Settings (HPV MISTICS)
Status: RECRUITING
Conditions: Human Papilloma Virus (HPV) Vaccine
Interventions: BEHAVIORAL: HPV MISTICS -Provider Level|BEHAVIORAL: HPV MISTICS - Parent Level|BEHAVIORAL: HPV MISTICS- HPV Vaccine Champion Level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Fall Prevention Program on the Number of Falls Among Elderly Following Total Knee Replacement
Status: RECRUITING
Conditions: Fall|Osteo Arthritis Knee|Total Knee Replacement
Interventions: OTHER: fall prevention programe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Biomarkers in Tissue Samples From Patients With Ductal Breast Carcinoma in Situ
Status: COMPLETED
Conditions: Breast Cancer
Interventions: GENETIC: RNA analysis|GENETIC: gene expression analysis|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Misoprostol vs. Sublingual Misoprostol and Laminaria For Second Trimester Termination of Pregnancy
Status: UNKNOWN
Conditions: Other Abortion
Interventions: DRUG: Cytotec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Efficacy of a New Piezoelectric Technique for Wisdom Teeth Extraction
Status: UNKNOWN
Conditions: Impacted Third Molar Tooth
Interventions: PROCEDURE: piezoelectric extraction|PROCEDURE: conventional extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of NMN as an Anti-ageing Supplement in Middle Aged and Older (40-65 Years) Adults
Status: COMPLETED
Conditions: Aging
Interventions: DRUG: Nicotinamide Mononucleotide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Vitrectomy With ILM Peeling in Myopic Macular Hole With Only Posterior Retinal Detachment
Status: ACTIVE_NOT_RECRUITING
Conditions: Retinal Detachment
Interventions: PROCEDURE: Vitrectomy with ILM peeling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab (Erbitux) in Combination With Cisplatin or Carboplatin and 5-Fluorouracil in the First Line Treatment of Subjects With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck (EXTREME)
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Cetuximab + Platinum (Cisplatin or Carboplatin) + 5Fluorouracil (5-FU)|DRUG: Platinum (Cisplatin or Carboplatin) + 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Therapy to Improve Physical and Psychological Symptoms and Quality of Life for End-of-life Patients on a Palliative Care Unit
Status: COMPLETED
Conditions: End-of-Life|Physical Suffering|Psychological Distress
Interventions: OTHER: Standardized Virtual Reality|OTHER: Control|OTHER: Personalized Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of ABBV-927 and ABBV-181, an Immunotherapy, in Participants With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors Cancer
Interventions: DRUG: ABBV-927|DRUG: ABBV-927|DRUG: ABBV-181
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alrex® Versus Patanol in the Treatment of Seasonal Allergic Conjunctivitis(SAC)
Status: COMPLETED
Conditions: Seasonal Allergic Conjunctivitis
Interventions: DRUG: Loteprednol etabonate 0.2%|DRUG: Olopatadine 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Echogenic Versus Stimulating Needle and Catheter for Sciatic Blocks
Status: COMPLETED
Conditions: Osteoarthritis Knee|Postoperative Pain
Interventions: DEVICE: echogenic needle and catheter|DEVICE: Neurostimulation to position needle and catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ManNAc in Subjects With Primary Podocyte Diseases
Status: COMPLETED
Conditions: Kidney Disease
Interventions: DRUG: N-acetyl D-mannosamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This Study Tests the Safety of Inhaled BAY1237592, How the Drug is Tolerated and How it Effects Patients With High Blood Pressure in the Arteries of the Lungs in the Two Different Disease Groups Pulmonary Arterial Hypertension (PAH) and Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: BAY1237592
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vaniprevir Plus PegIntron®/Ribavirin in Japanese Participants With Chronic Hepatitis C Who Are Non-responders to Previous Treatment (MK-7009-045)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Vaniprevir|BIOLOGICAL: peg-IFN|DRUG: ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plerixafor and Filgrastim Following Cyclophosphamide for Stem Cell Mobilization in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Refractory Multiple Myeloma|Stage I Multiple Myeloma|Stage II Multiple Myeloma|Stage III Multiple Myeloma
Interventions: DRUG: plerixafor|BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|PROCEDURE: autologous hematopoietic stem cell transplantation|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplantation and T-Cell Add-Back to Treat Bone Marrow Malignances
Status: COMPLETED
Conditions: Immunosuppression|Leukemia
Interventions: DEVICE: SOLEX 300i Stem Cell Selection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Iron Uptake From Micronutrient Fortified Powder Versus From Tailored Control in Milk
Status: COMPLETED
Conditions: Growth and Development
Interventions: DIETARY_SUPPLEMENT: Test|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Efficacy and Safety of Ivermectin in COVID-19 Prevention
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Ivermectin Tablets|DRUG: Matching placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An Investigation of the Efficacy of Oral Nutritional Supplements in Participants at Risk of Malnutrition
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: Standard ONS|DIETARY_SUPPLEMENT: High Energy, low volume ONS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Modulation of Frontoparietal Dynamics Underlying Adolescent Working Memory Deficits
Status: RECRUITING
Conditions: ADHD
Interventions: DEVICE: Intermittent Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: RCT on Nonoperative Versus Operative Treatment for Acute Complete tearS of the Ulnar Collateral ligAment of the Thumb
Status: RECRUITING
Conditions: Ulnar Collateral Ligament Sprain|Skier's Thumb
Interventions: PROCEDURE: Cast immobilization|PROCEDURE: Surgical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Application of ctDNA Dynamic Monitoring in Neoadjuvant Therapy for HER2-positive Breast Cancer Patients
Status: RECRUITING
Conditions: Breast Cancer|Neoadjuvant|HER2-positive Breast Cancer|Circulating Tumor DNA
Interventions: DIAGNOSTIC_TEST: ctDNA-MRD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Chemotherapy in Treating Patients With Prostate Cancer That Has Not Responded to Hormone Therapy
Status: UNKNOWN
Conditions: Pain|Prostate Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: docetaxel|DRUG: doxorubicin hydrochloride|PROCEDURE: pain therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Rofecoxib and a Narcotic Analgesic to Treat Pain Following Arthroscopic Surgery (0966-179)(COMPLETED)
Status: COMPLETED
Conditions: Pain, Postoperative Arthroscopy
Interventions: DRUG: MK0966 / Duration of Treatment: 1 Days|DRUG: Comparator: acetaminophen (+) hydrocodone bitartrate / Duration of Treatment: 1 Days|DRUG: Comparator: placebo (unspecified) / Duration of Treatment: 1 Days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin Infusions and Blood Loss in Patients Undergoing Elective Cesarean Delivery.
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Oxytocin Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of L-Citrulline Supplementation on NAFLD in Adolescents With Obesity
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease|Obesity
Interventions: DIETARY_SUPPLEMENT: L-Citrulline supplement|DIETARY_SUPPLEMENT: Carboxymethyl cellulose supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Pantovigar® Vegan in Female Subjects With Diffuse Hair Loss
Status: COMPLETED
Conditions: Diffuse Hair Loss in Females
Interventions: DIETARY_SUPPLEMENT: Pantovigar® vegan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subconjunctival Bupivacaine in Strabismus Surgery
Status: UNKNOWN
Conditions: Anesthesia, Local
Interventions: DRUG: Iocal anaesthetic bupivacaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effectiveness of Cinnamon on Insulin Resistance ( ECIRCCOS ) December 1, 2019
Status: UNKNOWN
Conditions: Obesity, Childhood|Insulin Resistance|Insulin Sensitivity
Interventions: DIETARY_SUPPLEMENT: Cinnamon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of 2 NovoFine® Needles on the Reflux of Insulin
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Delivery Systems
Interventions: DEVICE: NovoFine® needle 6 mm|DEVICE: NovoFine® needle 8 mm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy of Induction Chemotherapy With Gemcitabine and Carboplatin for Operable Non-small-cell Lung Cancer Before Surgery
Status: UNKNOWN
Conditions: Lung Neoplasms
Interventions: DRUG: gemcitabine, carboplatin|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CatchU: A Quantitative Multisensory Falls-Assessment Study
Status: RECRUITING
Conditions: Fall Injury|Age Problem|Well Aging|Sensory Disorders
Interventions: OTHER: CatchU Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Promising Tool for Predicting Consciousness Evolution in Prolonged Disorders of Consciousness
Status: COMPLETED
Conditions: Disorder of Consciousness
Interventions: DRUG: Zolpidem Tartrate Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Impact of Beef's Unique Food Matrix on Human Health
Status: COMPLETED
Conditions: Cholesterol, LDL|Cholesterol, HDL|Research Subjects
Interventions: DIETARY_SUPPLEMENT: Low-fat ground beef|DIETARY_SUPPLEMENT: High-fat ground beef
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sequential Low-dose Decitabine With PD-1/CD28 CD19 CAR-T in Relapsed or Refractory B-cell Lymphoma
Status: UNKNOWN
Conditions: Objective Response Rate
Interventions: BIOLOGICAL: CD19 PD-1/CD28 CAR-T Plus Low Dose Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of PCSO-524 Relative to a Comparator Product
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Fish Oil|DIETARY_SUPPLEMENT: PCSO-524
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Improving Executive Function in Korean Children With Autism
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: CHUCK CHUCK SKILLS: CHild's Understanding of Cognitive sKills|BEHAVIORAL: Parent Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Monteleukast Versus Inhaled Mometasone for Treatment of Otitis Media With Effusion in Children
Status: COMPLETED
Conditions: Otitis Media With Effiusion
Interventions: DRUG: Monteleukast|DRUG: Mometasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spectacle Films Utilising S.T.O.P.® Technology for Slowing Down Myopia Progression in Children
Status: RECRUITING
Conditions: Myopia
Interventions: DEVICE: Single vision spectacle lens|DEVICE: Single vision spectacle lens + S.T.O.P.® Kit 1|DEVICE: Single vision spectacle lens + S.T.O.P.® Kit 2|DEVICE: Single vision spectacle lens + S.T.O.P.® Film|DEVICE: Standard single vision spectacle lens + S.T.O.P.® Kit 1 or 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability of MRZ-99030 Eye Drops in Healthy Volunteers and Glaucoma Patients
Status: COMPLETED
Conditions: Healthy Volunteers and Glaucoma Patients
Interventions: DRUG: MRZ-99030 eye drops 5mg/mL|DRUG: MRZ-99030 eye drops 20mg/mL|DRUG: Placebo to MRZ-99030 eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-finding Study of Intrathecal Paracetamol Administered Immediately Before Spinal Anaesthesia
Status: COMPLETED
Conditions: Phase 1: Pain Management|Phase 2: Pain Management
Interventions: DRUG: Paracetamol 3%|DRUG: Placebo injection containing Saline solution 0.9%|DRUG: Hyperbaric Bupivacaine HCl 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility of Virtual Reality in Children With Neuromuscular Disease, Effectiveness of Virtual Reality and Biofeedback
Status: UNKNOWN
Conditions: Neuromuscular Disease|Duchenne Muscular Dystrophy|Spinal Muscular Atrophy|Virtual Reality|Biofeedback
Interventions: OTHER: Virtual Reality Training|OTHER: Biofeedback Training|OTHER: Conventional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antibody Therapy in Treating Patients With Refractory or Relapsed Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia
Status: TERMINATED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: bispecific antibody 4G7xH22|BIOLOGICAL: sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT