pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Imidapril and Candesartan on Fibrinolysis and Insulin-Sensitivity in Patients With Mild to Moderate Hypertension
Status: UNKNOWN
Conditions: Essential Hypertension
Interventions: DRUG: Imidapril|DRUG: Candesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab Deruxtecan in First-line HER2-positive Locally Advanced/MBC Patients Resistant to Trastuzumab+Pertuzumab
Status: RECRUITING
Conditions: Locally Advanced Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: Trastuzumab deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical and Chemical Study of Atherosclerosis Mechanisms
Status: COMPLETED
Conditions: Myocardial Infarction|Coronary Artery Diseases|Diabetes Mellitus, Type 2|Atherosclerosis of Femoral Artery
Interventions: DRUG: Conventional treatment|DIETARY_SUPPLEMENT: Weight loss treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Edwards Cardioband System ACTIVE Pivotal Clinical Trial (ACTIVE)
Status: TERMINATED
Conditions: Functional Mitral Regurgitation|Mitral Regurgitation|Mitral Insufficiency
Interventions: DEVICE: Edwards Cardioband System|DRUG: Guideline Directed Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of ABP 501 Compared to Adalimumab in Subjects With Moderate to Severe Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: BIOLOGICAL: ABP 501|BIOLOGICAL: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Mirabegron to Increase BP in Patients With POTS
Status: RECRUITING
Conditions: Postural Orthostatic Tachycardia Syndrome|Chronic Orthostatic Intolerance|Syncope
Interventions: DRUG: Mirabegron 50 MG|DRUG: Mirabegron 25 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Insulin vs Subcutaneous Insulin Infusion in Intrapartum Management of Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes|Pregnancy, High Risk
Interventions: DRUG: Insulin|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Assess Telemonitoring of Gleevec (Imatinib Mesylate) or Tasigna (Niltinib) Therapy
Status: TERMINATED
Conditions: Chronic Phase CML
Interventions: BEHAVIORAL: no access to eMedonline|BEHAVIORAL: eMedonline access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Quality of Life and Symptoms in Patients With Newly Diagnosed Myelodysplastic Syndromes
Status: UNKNOWN
Conditions: Adult|Myelodysplastic Syndromes
Interventions: OTHER: questionnaire administration|OTHER: fatigue assessment and management|OTHER: observation|OTHER: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study To Evaluate The Effect Of Food On The Behavior Of Tofacitinib Modified Release 11 Milligram Tablets In Healthy Western And Japanese Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: tofacitinib modified-release (MR) formulation|DRUG: tofacitinib modified-release (MR) formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Investigational Scan (rh PSMA 7.3 PET/MRI) for the Detection of Recurrent Disease and Aid in Radiotherapy Planning in Biochemically Recurrent Prostate Cancer
Status: COMPLETED
Conditions: Biochemically Recurrent Prostate Carcinoma|Localized Prostate Carcinoma|Prostate Adenocarcinoma
Interventions: DRUG: Fluorine F 18 rhPSMA-7.3|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Test Whether Different Doses of BI 1291583 Help People With Bronchiectasis
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: DRUG: BI 1291583|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Belumosudil in Subjects With Diffuse Cutaneous Systemic Sclerosis
Status: TERMINATED
Conditions: Diffuse Cutaneous Systemic Sclerosis
Interventions: DRUG: Belumosudil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bladder Lavage as Decontamination Method for Asymptomatic Bacteriuria With Uropathogens in Catheterized Patients
Status: WITHDRAWN
Conditions: Catheter Related Infections
Interventions: PROCEDURE: bladder lavage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Gain Insights in Treatment Patterns and Outcomes in Patients With Atherosclerosis Prescribed to Xarelto in Combination With Acetylsalicylic Acid
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DRUG: Rivaroxaban (BAY59-7939, Xarelto)|DRUG: Acetylsalicylic acid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Two Adagrasib Dosing Regimens in NSCLC With KRAS G12C Mutation (KRYSTAL 21)
Status: RECRUITING
Conditions: Advanced Cancer|Metastatic Cancer|Malignant Neoplasm of Lung
Interventions: DRUG: Adagrasib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety & Effectiveness of PRESTIGE® LP Cervical Disc vs. Anterior Cervical Fusion in Cervical DDD
Status: COMPLETED
Conditions: Cervical Degenerative Disc Disease
Interventions: DEVICE: PRESTIGE® LP Cervical Disc|DEVICE: ATLANTIS Anterior Cervical Plate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Open-Label, Dose-Escalation Study of CC-11006 In Subjects With Low- or Intermediate-1 Risk Myelodysplastic Syndromes
Status: TERMINATED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: CC-11006
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corrective Calcaneal Kinesiology Tape in Adolescents With Pronated Foot
Status: ENROLLING_BY_INVITATION
Conditions: Physical Disability|Physical Therapy Modalities
Interventions: DEVICE: Corrective Kinesiology taping|DEVICE: Non corrective kinesiology tape|OTHER: Home exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Postoperative Skin Disinfection With Chlorhexidine on Bacterial Colonization
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: DRUG: Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Novel Cardiovascular Biomarkers in Patients With Kidney Disease
Status: NOT_YET_RECRUITING
Conditions: Haemodialysis Complication|Major Adverse Cardiac Events
Interventions: DIAGNOSTIC_TEST: Cardiac Biomarkers|DIAGNOSTIC_TEST: Lipidomics|DIAGNOSTIC_TEST: Proteomics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2 Study Comparing 2 Intermittent Dosing Schedules of Duvelisib in Subjects With Indolent Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Indolent Non-Hodgkin Lymphoma
Interventions: DRUG: Duvelisib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improvement of Humoral Immune Response With Hemodialysis on BK-F Membrane: Correlation to Soluble CD40 Clearing
Status: COMPLETED
Conditions: Chronic Renal Failure|Humoral Immune Alterations
Interventions: PROCEDURE: High flux polymethylmetacrylate membrane|PROCEDURE: Polysulfone membrane|BIOLOGICAL: Hepatitis B serological control|BIOLOGICAL: Seric sCD40 level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improved Immunology Outcomes Associated With Lactoferrin Fortified With HMO in Infant Formula
Status: RECRUITING
Conditions: Flu|Cold
Interventions: DIETARY_SUPPLEMENT: Feihe Investigational Formula|DIETARY_SUPPLEMENT: Control Formula|OTHER: Breastfeeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-inferiority Trial on Monoclonal Antibodies in COVID-19
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: Bamlanivimab Etesevimab|DRUG: Sotrovimab|DRUG: Casirivimab-Imdevimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Auricular Acupressure and Fluid Restriction Program on Salivary Flow and Fluid Adherence in Children on Hemodialysis
Status: COMPLETED
Conditions: Hemodialysis Complication
Interventions: BEHAVIORAL: Fluid Restriction Program|OTHER: Intervention Bundle (Fluid Restriction Program and Auricular Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multi-modal, Physician-centered Intervention to Improve Guideline-concordant Prostate Cancer Imaging
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Clinical Order Check|BEHAVIORAL: Academic Detailing|BEHAVIORAL: Audit and Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Short-duration Selective Brain Cooling for Patients Undergoing Mechanical Thrombectomy
Status: SUSPENDED
Conditions: Hypothermia|Stroke, Acute
Interventions: DRUG: selective brain cooling by cold saline perfusion|DEVICE: mechanical thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plant-based Dietary Protein and Resistance-training Adaptations
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: whey protein|DIETARY_SUPPLEMENT: soy protein
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Special Drug Use Investigation of Ciproxan Injection in Pediatrics
Status: COMPLETED
Conditions: Cystitis / Pyelonephritis / Cystic Fibrosis / Anthrax
Interventions: DRUG: Cipro (Ciprofloxacin, BAYQ3939)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: IMPACT OF POLYCYCLIC AROMATIC HYDROCARBONS (PAH) ON IN VITRO FERTILIZATION
Status: UNKNOWN
Conditions: Infertility
Interventions: BIOLOGICAL: IN VITRO FERTILIZATION
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Blood Flow Restriction Following Hip Arthroscopy
Status: RECRUITING
Conditions: Labral Tear, Glenoid|Femoral Acetabular Impingement
Interventions: BEHAVIORAL: Blood Flow Restriction Rehabilitative Therapy|BEHAVIORAL: Sham BFR Rehabilitative Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HA Residents With PVD, Pulmonary Artery Pressure (PAP) Assessed at HA (2840m) With and Without Supplemental Oxygen Therapy (SOT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Vascular Disorder|Pulmonary Artery Hypertension|Chronic Thromboembolic Pulmonary Hypertension
Interventions: OTHER: Supplemental oxygen therapy|OTHER: Sham Oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Relative Bioavailability of a Fixed-dose Combination Tablet of VX-121/Tezacaftor/Deutivacaftor
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: VX-121/TEZ/D-IVA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of A0001 in Patients With the A3243G Mitochondrial DNA Point Mutation
Status: TERMINATED
Conditions: Neuromuscular Disease
Interventions: DRUG: A0001 (alpha-tocopherolquinone)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CareToy Early Intervention in Infants at Risk for Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DEVICE: CareToy intervention|OTHER: Infant Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Cisplatin as First Line Combination Therapy in Patients With Triple-negative MBC
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: gemcitabine and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Metoprolol and Tramadol With Remifentanil in Endoscopic Sinus Surgery
Status: COMPLETED
Conditions: Nasal Polyps
Interventions: DRUG: Remifentanil|DRUG: Tramadol|DRUG: Metoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Vedolizumab Monotherapy Vs Combination Therapy With Tacrolimus in UC
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: Tacrolimus|DRUG: Vedolizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Hyperbaric Oxygen Therapy on Pneumonia Complicating Stroke
Status: UNKNOWN
Conditions: Hyperbaric Oxygen Therapy|Stroke|Pneumonia
Interventions: PROCEDURE: hyperbaric oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation and Antisocial Behavior
Status: ACTIVE_NOT_RECRUITING
Conditions: Aggression
Interventions: DEVICE: Transcranial direct current stimulation|DEVICE: Sham transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: MS-ResearchBiomarkerS
Status: RECRUITING
Conditions: Multiple Sclerosis|Multiple Sclerosis, Relapsing-Remitting|Multiple Sclerosis, Primary Progressive|Multiple Sclerosis, Secondary Progressive|Clinically Isolated Syndrome|Radiologically Isolated Syndrome|Neuromyelitis Optica Spectrum Disorders|Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease|Neurologic Autoimmune Disease|Neurologic Disorder|Healthy Aging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Integrated BA and HIV RR Counseling for MSM With Stimulant Abuse
Status: COMPLETED
Conditions: Stimulant Abuse|HIV Prevention|Substance Abuse
Interventions: BEHAVIORAL: IMPACT|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of EDG-7500 in Adults With Hypertrophic Cardiomyopathy (CIRRUS-HCM)
Status: RECRUITING
Conditions: Hypertrophic Cardiomyopathy
Interventions: DRUG: EDG-7500|DRUG: EDG-7500
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Risperidone Long-Acting Injection With Oral Antipsychotic in the Treatment of Early Psychosis
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder|Psychotic Disorders
Interventions: DRUG: Risperidone long-acting injection (LAI)|DRUG: Oral Antipsychotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: University of California, San Diego (UCSD) Suramin Autism Treatment-1 (SAT1) Trial
Status: COMPLETED
Conditions: Autism Spectrum Disorders
Interventions: DRUG: Suramin|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Pregabalin on Propofol Induction Dose
Status: COMPLETED
Conditions: Anesthesia, General|Laparoscopic Surgery
Interventions: DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COmbining Oral Letrozole and Clomiphene for Ovarian Stimulation (COOL-COS) Associated With Corifollitropin Alfa: a Pilot Study
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: COOL-COS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Marrow Irradiation & Autologous Stem Cell Transplantation for Relapsed or Refractory Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: RADIATION: Total Marrow Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Grass Sublingual Tablet in Adults (P05238 AM3)(COMPLETED)
Status: COMPLETED
Conditions: Rhinoconjunctivitis|Rhinitis|Conjunctivitis|Allergy
Interventions: DRUG: Placebo|BIOLOGICAL: SCH 697243|DRUG: Loratadine 10 mg Rescue Treatment|DRUG: Olopatadine 0.1% Rescue Treatment|DRUG: Mometasone 50 mcg Rescue Treatment|DRUG: Prednisone 5 mg Rescue Treatment|DRUG: Albuterol sulfate 108 mcg|DRUG: Fluticasone propionate 44 mcg|DRUG: Prednisone 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Motor Attention Training for Attention Deficit Hyperactivity Disorder (ADHD)
Status: RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Tai Chi|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Combined Endocrine and HER2 Target Therapy in Postmenopausal Women With ER and Her2 Positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Letrozole, Lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Intravenous Recombinant Human IL-15 in Adults With Refractory Metastatic Malignant Melanoma and Metastatic Renal Cell Cancer
Status: COMPLETED
Conditions: Melanoma|Carcinoma, Renal Cell
Interventions: BIOLOGICAL: rh IL-15
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study Between AZD3480 and Aripiprazole in Healthy Subjects
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: AZD3480|DRUG: Placebo|DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Disitamab Vedotin Combined With PD-1 and Neoadjuvant Chemotherapy for Locally Advanced Gastric Cancer（RC48-C018）
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Disitamab Vedotin Combined With PD-1 and Neoadjuvant Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel, Cisplatin and Capecitabine as Neoadjuvant Chemotherapy for Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel , Cisplatin , Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of HP011-101 to Standard Care for Stage I-II Pressure Ulcers in Subjects With Spinal Cord Injury
Status: TERMINATED
Conditions: Pressure Ulcers|Spinal Cord Injury
Interventions: DRUG: HP011-101 (Xenaderm Ointment)|DRUG: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATG/PTCy in Haplo-PBSCT Randomized Controlled,Multi-center
Status: COMPLETED
Conditions: Myeloid Tumor
Interventions: DRUG: ATG/PTCy|DRUG: standard ATG|DRUG: standard PTCy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Dose Titration Study of Botulinum Toxin Type A to Treat Spasticity in the Leg and Arm
Status: COMPLETED
Conditions: Spasticity of the Upper and Lower Limb Due to Cerebral Causes
Interventions: DRUG: IncobotulinumtoxinA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermountain Healthcare's Enhanced Recovery Protocol for Colon Surgery With and Without Alvimopan Use
Status: COMPLETED
Conditions: Ileus
Interventions: DRUG: Alvimopam|DRUG: 300 mg Polyethylene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Repetitive Synchronized Associative Stimulation Neuromodulation Approach for Spinal Cord Injury Patients
Status: NOT_YET_RECRUITING
Conditions: SCI - Spinal Cord Injury
Interventions: OTHER: Intermittent theta burst stimulation (iTBS)|OTHER: Functional electrical stimulation (FES)|OTHER: Transcutaneous spinal cord stimulation (TSCS)|OTHER: Sham Intermittent theta burst stimulation (iTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating PK, Tolerability, and Safety of Rifapentine and Isoniazid in Pregnant and Postpartum Women
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: Rifapentine (RPT)|DRUG: Isoniazid (INH)|DIETARY_SUPPLEMENT: Pyridoxine (vitamin B6)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telerehabilitation Program Bases Aerobic and Baduanjin Exercises in Post Stroke Elderly Patients
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: Telerehabilitation program bases aerobic and Baduanjin exercises|OTHER: Telerehabilitation program bases aerobic exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fasudil fOr redUcing elopemeNt and Spatial Disorientation
Status: COMPLETED
Conditions: Dementia
Interventions: DRUG: Oral Fasudil 90 mg/day|DRUG: Oral Fasudil 180 mg/day|DRUG: Oral Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PREFERENTIAL Study
Status: WITHDRAWN
Conditions: Cataract Surgery|Glaucoma Surgery
Interventions: DRUG: Dextenza 0.4Mg Ophthalmic Insert|DRUG: Prednisolone Acetate 1% Ophthalmic Suspension [PRED FORTE]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Ultrasound (EUS) Intratumoral Injection of CAR-NK Cells in the Treatment of Advanced Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer Non-resectable
Interventions: BIOLOGICAL: CAR-NK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Human Embryonic Stem Cell (hESC)-Derived Mesenchymal Stem Cells in Interstitial Cystitis
Status: UNKNOWN
Conditions: Interstitial Cystitis|Stem Cell Transplant|Mesenchymal Stem Cell
Interventions: DRUG: MR-MC-01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selective Lymph Node Dissection Using Fluorescent Dye in Node-positive Breast Cancer
Status: UNKNOWN
Conditions: Breast Neoplasms
Interventions: PROCEDURE: Axillary lymph node dissection|DRUG: Indocyanine green|DEVICE: Imaging devices
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Acupuncture-assisted-anesthesia to Improve Postoperative Outcome After Digestive Surgery in Elderly Patients
Status: COMPLETED
Conditions: Postoperative Complications|Surgery
Interventions: OTHER: TES(transcutaneous electric stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: caspofungin acetate|DRUG: liposomal amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Effectiveness of Restylane Lyft With Lidocaine for Augmentation of the Chin Region to Improve the Chin Profile
Status: ACTIVE_NOT_RECRUITING
Conditions: Chin Augmentation|Chin Retrusion
Interventions: DEVICE: Restylane Lyft with Lidocaine|DEVICE: Juvederm Voluma XC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Baricitinib (LY3009104) in Adults With Severe or Very Severe Alopecia Areata
Status: ACTIVE_NOT_RECRUITING
Conditions: Alopecia Areata
Interventions: DRUG: Baricitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting Beta Cell Dysfunction With Liraglutide or Golimumab in Longstanding T1D
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Liraglutide|DRUG: Golimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Carboplatin and Paclitaxel With or Without MEDI-575 in Untreated, Advanced Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: MEDI-575
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: How Much is Too Much: Assessing Varying Pressure Pump Pressures in Post Operative Pain Control in Shoulder Arthroscopy.
Status: UNKNOWN
Conditions: Shoulder Arthroscopy
Interventions: PROCEDURE: Arthroscopic rotator cuff repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The VOLTAIRE-X Trial Looks at the Effect of Switching Between Humira® and BI 695501 in Patients With Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Humira®|DRUG: BI 695501
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Instrumental Activities of Daily Living Approach in Home Environment for Patients With Stroke
Status: COMPLETED
Conditions: Stroke|Activities of Daily Living
Interventions: BEHAVIORAL: Approach-Instrumental Activities of Daily Living|BEHAVIORAL: Home health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physiotherapy in Lumbar Disc Pathologies
Status: COMPLETED
Conditions: Lumbar Disc Disease|Lumbar Disc Herniation|Low Back Pain, Mechanical|Low Back Strain
Interventions: OTHER: Effectiveness of four physical therapy approaches (soft tissue manual therapy, Kinesio® Taping techniques, stabilization exercises and reflex therapy) for treating lumbar disc pathologies.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pediatric Study to Evaluate Treatment of Persistent Moderate or Severe Asthma With the Association Fluticasone 250 mcg/Dose and Salmeterol 50 mcg/Dose - ADERE PROJECT
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: Telephone follow-up|OTHER: No telephone follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probenecid on Pexidartinib Pharmacokinetics
Status: COMPLETED
Conditions: Pharmacokinetics in Healthy Volunteers
Interventions: DRUG: Pexidartinib|DRUG: Probenecid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Application of Rectus Sheath Block based-on Incision in Upper Abdominal Surgery
Status: COMPLETED
Conditions: Opioid Consumption
Interventions: PROCEDURE: Subcostal TAP|PROCEDURE: Modified RSB|OTHER: General anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Specialist Dietetic Intervention in Malnourished Patients With Fibrotic ILD: a Randomised Controlled Pilot Trial
Status: RECRUITING
Conditions: Interstitial Lung Disease
Interventions: OTHER: Dietetic intervention|OTHER: Diet sheet (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Local Cannabidiol on Clinical and Inflammatory Outcomes in Periodontal Maintenance Patients.
Status: WITHDRAWN
Conditions: Periodontitis, Adult|Inflammation Gum
Interventions: DRUG: cannabidiol|DEVICE: floss|DEVICE: proxabrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ICARuS Post-operative Intraperitoneal Chemotherapy (EPIC) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) After Optimal Cytoreductive Surgery (CRS) for Neoplasms of the Appendix, Colon or Rectum With Isolated Peritoneal Metastasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Appendix Cancer|Colorectal Cancer
Interventions: PROCEDURE: Cytoreductive Surgery|DRUG: HIPEC with Mitomycin-C|DRUG: EPIC with FUDR and Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maternal and Fetal Outcome of CKD Mother Patient in Sohag Governorate
Status: RECRUITING
Conditions: CKD PREGNANT WOMEN
Interventions: DIAGNOSTIC_TEST: Serum creatinine|DIAGNOSTIC_TEST: Alb /creat ratio or 24h urine protein|DIAGNOSTIC_TEST: Serum electrolyte|DIAGNOSTIC_TEST: Urine analysis|DIAGNOSTIC_TEST: Abdominal ultrasound|DIAGNOSTIC_TEST: Renal biobsy|OTHER: Clinical assesment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antrum Size, Glucagon-like Peptide 1 Levels and Glycemic Control After Sleeve Gastrectomy in Morbid Obese Diabetic Adolescents
Status: COMPLETED
Conditions: Adolescent Obesity
Interventions: PROCEDURE: Laparoscopic sleeve gastrectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase III Clinical Trial of a Haemophilus Influenzae Type b (Hib) Conjugate Vaccine
Status: COMPLETED
Conditions: Haemophilus Influenza
Interventions: BIOLOGICAL: Hib conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Self Cranial Electrical Stimulation (CES) for Pain in Older Adults With Knee Osteoarthritis (Self CES for Knee Pain)
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: DEVICE: Cranial Electrical Stimulation (CES)|DEVICE: Sham-CES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TACE Combined With Tyrosine Kinase Inhibitors and Tislelizumab in Unresectable Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Transarterial chemoembolization combined with Tyrosine Kinase Inhibitors and Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunosuppression Withdrawal for Stable Pediatric Liver Transplant Recipients
Status: COMPLETED
Conditions: Liver Transplant Recipients|Liver Transplantation|Immunosuppression
Interventions: DRUG: Immunosuppression withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pioglitazone on Neointima Volume and Inflammatory Markers
Status: COMPLETED
Conditions: Diabetes Mellitus|Coronary Artery Stenosis
Interventions: DRUG: Pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test a Potential New Treatment for COPD Patients Suffering From the Common Cold or Influenza
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Interferon Beta-1A|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Computer Assisted Cognitive Rehabilitation on Patients With Stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: BEHAVIORAL: Computer Assited Cognitive rehabilitation|BEHAVIORAL: Conventional Cognitive Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long-term Safety and Efficacy of Prebiotic Enriched Infant Formula
Status: COMPLETED
Conditions: Infection|Microbial Colonization|Healthy
Interventions: OTHER: Supplemented formula|OTHER: Standard formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Ozanimod|DRUG: Fingolimod|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety & Immunogenicity of IMNN-101 Administered in Healthy Adults Previously Vaccinated Against SARS-CoV-2
Status: RECRUITING
Conditions: SARS CoV 2 Infection
Interventions: BIOLOGICAL: IMNN-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ANAVEX2-73 Study in Parkinson's Disease Dementia
Status: COMPLETED
Conditions: Parkinsons Disease With Dementia
Interventions: DRUG: High dose ANAVEX2-73|DRUG: Mid dose ANAVEX2-73|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Individual Dietary Counseling Based on Taste-tests in Patients With Hematological Cancer in Cytostatic Therapy
Status: UNKNOWN
Conditions: Hematological Malignancy
Interventions: DIETARY_SUPPLEMENT: Taste-test|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Management of Pain in Oral Lichen Planus
Status: COMPLETED
Conditions: Oral Lichen Planus
Interventions: DRUG: 0.1 % topical triamcinolone acetonide|DEVICE: SIROIaser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: COMPArative Study of the Consequence on innaTe Immune Response du to Bacterial or Viral Infection in Patients Admitted to Intensive Care Unit
Status: RECRUITING
Conditions: Viral Infection|Sepsis
Interventions: OTHER: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioactive Restorative Material in Non-Carious Cervical Lesions
Status: COMPLETED
Conditions: Cervical Lesion
Interventions: OTHER: Dentin Conditioning|OTHER: RM-GIC|OTHER: 1-step adhesive|OTHER: Cention N|OTHER: Dentin roughness|OTHER: Gingival retentive groove preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Sympathetic Ganglion, High-voltage Pulsed Radiofrequency Ablation of Peripheral Neuralgia
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Foot
Interventions: RADIATION: Pulsed radio frequency therapy|OTHER: sham operation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lisdexamfetamine Dimesylate in the Treatment of Adult ADHD With Anxiety Disorder Comorbidity
Status: COMPLETED
Conditions: Adult Attention Deficit Hyperactivity Disorder (ADHD) With Co-occuring Anxiety and Depressive Disorders
Interventions: DRUG: Lisdexamfetamine Dimesylate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Avoiding Postinduction Hypotension: the Clinical ZERO-HYPOTENSION Proof-of-concept Study
Status: COMPLETED
Conditions: Hypotension|Anesthesia|Hypotension on Induction
Interventions: PROCEDURE: Monitoring|PROCEDURE: Norepinephrine preparation|PROCEDURE: Propofol administration|PROCEDURE: Alarm adjustment|PROCEDURE: Intervention threshold
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fractional Laser and Steroid Ointment to Improve the Old Scar After Thyroidectomy
Status: COMPLETED
Conditions: Thyroid; Wound|Steroid Acne
Interventions: DEVICE: Laser-assisted drug delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive-Behavioral Therapy in Veterans With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Supportive Therapy (ST)|BEHAVIORAL: Cognitive Behavioral Therapy for Psychosis (CBTp)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Calorie Restriction Diets on Weight Reduction, Post weigh-in Recovery and Exercise Performance in Athletes
Status: COMPLETED
Conditions: Diet, Reducing
Interventions: DIETARY_SUPPLEMENT: calorie restriction diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Phase II Study Of Eribulin Mesylate With or Without Pembrolizumab For Metastatic Hormone Receptor Positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Eribulin Mesylate|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oatmeal Varieties on Glycemic and Insulinemic Responses in Healthy Individuals
Status: COMPLETED
Conditions: Glycemic Response
Interventions: OTHER: Oatmeal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison Between Dexamethasone and Ibuprofen on Pain Prevention and Control Following Surgical Implant Placement
Status: COMPLETED
Conditions: Pain Measurement
Interventions: DRUG: Ibuprofen 600 mg|DRUG: Dexamethasone 4 mg|DRUG: Placebo|DRUG: Acetaminophen 1000 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Electrocardiographic Effects of TA-8995
Status: COMPLETED
Conditions: Dyslipidaemia
Interventions: DRUG: TA-8995|DRUG: Moxifloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy of F8IL10 and Methotrexate in Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: F8IL10|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Resistant Mechanism of Eribulin and Bevacizumab for Advanced HER2 Negative Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Neoplasms|Neoplasm Metastasis|Drug Therapy|Bevacizumab
Interventions: DRUG: Eribulin|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gasdermin D Expression in Generalized Vitiligo Patients After Narrow-band Ultraviolet B Therapy
Status: NOT_YET_RECRUITING
Conditions: Vitiligo, Generalized
Interventions: DEVICE: narrow band ultraviolet-B
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing the Safety and Efficacy of Piperacillin/Tazobactam to Cefepime in Patients With Hematologic Malignancy or Lymphoma
Status: COMPLETED
Conditions: Hematologic Neoplasms
Interventions: DRUG: Piperacillin/Tazobactam (Tazocin)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Berry Extract Administration on Cognitive Health
Status: COMPLETED
Conditions: Cognitive Impairment|Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Brainport high dose|DIETARY_SUPPLEMENT: Brainport low dose|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Sintlimab Maintenance Therapy in Patients With Extensive Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Small Cell Lung Cancer|Extensive Disease|Adoptive Cellular Immunotherapy|Chemotherapy|Maintenance
Interventions: DRUG: sintilimab maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Semi-barbed Suture for Pulmonary Small Nodules Localization
Status: COMPLETED
Conditions: Suture|Nodule, Solitary Pulmonary|Video-Assisted Thoracoscopic Surgery
Interventions: DEVICE: absorbable semi-barbed suture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis
Status: NOT_YET_RECRUITING
Conditions: Hormone Receptor Positive HER-2 Negative Metastatic Breast Cancer
Interventions: DRUG: Zumsemetinib|DRUG: Capecitabine|DRUG: Zoledronic acid|DRUG: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT