pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Twice-daily Oral Direct Thrombin Inhibitor Dabigatran Etexilate in the Long Term Prevention of Recurrent Symptomatic VTE
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: dabigatran etexilate 150 mg twice daily (BID)|DRUG: matching placebo twice daily (BID)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effects of Ranolazine on Coronary Flow Reserve in Symptomatic Diabetic Patients and CAD
Status: COMPLETED
Conditions: Diabetes, Type I|Diabetes, Type II|Angina|Coronary Artery Disease
Interventions: DRUG: Ranolazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: To Evaluate the Efficacy and Safety of LuminoMark Injection in Patients With Nonpalpable Breast Lesions
Status: COMPLETED
Conditions: Breast Diseases
Interventions: DRUG: LuminoMark inj. 0.1mL|DRUG: LuminoMark inj. 0.2mL|DRUG: Charcotrace Inj.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alpha-lipoic Acid Adjunctive Therapy in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Oxidative Stress
Interventions: DRUG: Alpha-lipoic acid|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enasidenib in MDS &Non-proliferative Chronic Myelomonocytic Leukemia w/o IDH2 Mutation
Status: RECRUITING
Conditions: Leukemia|Leukemia, Myeloid|Monocytic Leukemia
Interventions: DRUG: Enasidenib mesylat dose escalation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety of Two Formulations of GSK Biologicals' Pneumococcal Vaccine (2830929A and 2830930A) When Administered in Healthy Infants
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Pneumococcal conjugate vaccine GSK2830929A|BIOLOGICAL: Pneumococcal conjugate vaccine GSK2830930A|BIOLOGICAL: Synflorix™|BIOLOGICAL: Prevnar 13™|BIOLOGICAL: Infanrix hexa™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Axitinib Before Surgery in Treating Patients With High-Risk Prostate Cancer
Status: COMPLETED
Conditions: Stage III Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: axitinib|PROCEDURE: therapeutic conventional surgery|OTHER: enzyme-linked immunosorbent assay|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EVALUATION OF PREFABRICATED CAD/CAM PEEK CROWNS USED IN PRIMARY MOLARS: A RANDOMISED CONTROLLED CLINICAL TRIAL
Status: RECRUITING
Conditions: Full Coverage Treatment
Interventions: PROCEDURE: Full coverage Crowns
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Volume Overload
Status: RECRUITING
Conditions: Acute Decompensated Heart Failure|Volume Overload|Edema
Interventions: DRUG: Acetazolamide|DRUG: Metolazone|DRUG: IV Loop Diuretics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Orthosis Use After Vaginal Reconstructive Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Pelvic Organ Prolapse
Interventions: DEVICE: Vaginal Orthosis (COSM Medical)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture in Prevention of Postoperative Sore Throat Due to Classical Laryngeal Mask
Status: UNKNOWN
Conditions: Acupuncture|Laryngeal Mask Airway|Pain, Postoperative|Sore Throat
Interventions: OTHER: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial on Probiotics in Preventing Hirschsprung's Disease Associated Entercolitis
Status: COMPLETED
Conditions: Probiotics|Hirschsprung's Disease Associated Enterocolitis
Interventions: DRUG: Bifico
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary Plaque
Status: NOT_YET_RECRUITING
Conditions: Lipidemia|Coronary Artery Disease|Plaque, Atherosclerotic
Interventions: DRUG: obicetrapib 10 mg + ezetimibe 10 mg FDC daily|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Terlipressin Administration in Septic Shock Refractory to Catecholamines
Status: UNKNOWN
Conditions: Septic Shock
Interventions: DRUG: terlipressin|DRUG: terlipressin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Postoperative Analgesia After Caesarean Section Under ALR: TAP Block Versus Catheter Scar Infiltration
Status: UNKNOWN
Conditions: Scheduled Caesarian Section
Interventions: DRUG: Ropivacaine|DEVICE: The infiltration continues catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib/Dexamethasone (BD), Followed By Autologous Stem Cell Transplantation and Maintenance Bortezomib/Dexamethasone For the Initial Treatment of Monoclonal Immunoglobulin Deposition Disease (MIDD) Associated With Multiple Myeloma and AL Amyloidosis
Status: COMPLETED
Conditions: Light Chain Deposition Disease (LCDD or MIDD)|Light Chain and Heavy Chain Deposition Disease (LHCDD or MIDD)|Monoclonal Immunoglobulin Deposition Disease (MIDD)|Amyloidosis
Interventions: DRUG: Bortezomib/Dexamethasone (BD), Followed By Autologous STC & Maintenance Bortezomib/Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Angiotensin II Receptor Blocker Azilsartan Study for Stronger Blood Pressure Lowering
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Azilsartan|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Social Interventions for Support During Treatment for Endometrial Cancer and Recurrence
Status: RECRUITING
Conditions: Endometrial Cancer
Interventions: BEHAVIORAL: Facilitated group support|BEHAVIORAL: 1:1 Peer Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Erectile Dysfunction With Low-intensity Extracorporeal Shockwave Therapy
Status: UNKNOWN
Conditions: Erectile Dysfunction Following Radiation Therapy
Interventions: DEVICE: low energy extracorporeal shockwave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Portion Size Strategies for Management of Body Weight
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Advice on diet, physical activity, and behavior change|BEHAVIORAL: Instruction in food portion size|OTHER: Provision of pre-portioned foods|BEHAVIORAL: Advice on healthy eating for weight loss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Women Engaging in Quitting Smoking Together
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Distress Tolerance Treatment for Weight Concern (DT-W)|BEHAVIORAL: Health Education (HE)|BEHAVIORAL: Smoking Cessation counseling|DRUG: Transdermal Nicotine Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Blood Flow Restriction Therapy in Perioperative Rehabilitation Following Achilles Tendon Rupture
Status: WITHDRAWN
Conditions: Achilles Tendon Rupture|Achilles Tendon Surgery
Interventions: DEVICE: Blood flow restriction augmented physical therapy|OTHER: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Theramine® in the Prevention of Migraine Headache
Status: TERMINATED
Conditions: Migraine Headaches
Interventions: DRUG: Theramine (medical food/old drug)|OTHER: Placebo (l-alanine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Fosaprepitant (MK0517) in Single Dose Schedule (0517-017)
Status: COMPLETED
Conditions: Chemotherapy-Induced Nausea and Vomiting (CINV)
Interventions: DRUG: Comparator: fosaprepitant dimeglumine|DRUG: Comparator: Aprepitant|DRUG: Dexamethasone|DRUG: Dexamethasone|DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Anakinra in Japanese Patients With Still's Disease (SJIA and AOSD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Still's Disease, Juvenile Onset|Still's Disease, Adult-Onset
Interventions: DRUG: Anakinra|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Infectivity, Safety and Immunogenicity of a Recombinant Live-Attenuated Respiratory Syncytial Virus Vaccine, LID/ΔM2-2/1030s, in RSV-Seronegative Infants and Children 6 to 24 Months of Age
Status: ACTIVE_NOT_RECRUITING
Conditions: RSV Infection
Interventions: BIOLOGICAL: RSV LID/ΔM2-2/1030s|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Gemcitabine, Docetaxel, and Capecitabine in Combination With Stereotactic Radiosurgery
Status: TERMINATED
Conditions: Pancreatic Neoplasms
Interventions: DRUG: GTX (gemcitabine, docetaxel and capecitabine)|RADIATION: stereotactic body radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utility of an Animated Bowel Biofeedback Training Routine to Improve Bowel Function in Individuals With SCI
Status: COMPLETED
Conditions: Spinal Cord Injury|Constipation|Fecal Incontinence|Neurogenic Bowel
Interventions: BEHAVIORAL: Bowel Biofeedback|BEHAVIORAL: Anorectal Manometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multimodal Intervention to Optimise Antimicrobial Use in Residential Aged Care Facilities (ENGAGEMENT Study)
Status: UNKNOWN
Conditions: Antimicrobial Stewardship|Antibiotics Causing Adverse Effects in Therapeutic Use
Interventions: BEHAVIORAL: Antimicrobial Stewardship ENGAGEMENT bundle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of Intravitreal Fluocinolone Acetonide Implants in Patients With Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: 0.59 mg fluocinolone acetonide intravitreal implant|DRUG: 2.1 mg fluocinolone acetonide intravitreal implant|PROCEDURE: standard of care laser photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Triptolide-Containing Formulation as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Status: UNKNOWN
Conditions: Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Interventions: DRUG: Triptolide-Containing Formulation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First Time Use of SD-809 in Huntington Disease
Status: COMPLETED
Conditions: Chorea
Interventions: DRUG: SD-809|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Airway Collapse in Patients With Mounier-Kuhn Syndrome: Titration With Positive Pressure to Reduce Collapse
Status: UNKNOWN
Conditions: Mounier-Kuhn Syndrome
Interventions: PROCEDURE: Non invasive ventilation - Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial Assessing Efficacy, Safety and Tolerability of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition in Paediatric Subjects With Genetic Low-Density Lipoprotein (LDL) Disorders
Status: COMPLETED
Conditions: Heterozygous Familial Hypercholesterolemia
Interventions: DRUG: Evolocumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Two Fertility Protocols in Obese Polycystic Ovary Syndrome Patients
Status: UNKNOWN
Conditions: Obese|Infertility|Polycystic Ovary Syndrome
Interventions: PROCEDURE: IVM (In Vitro Maturation) Treatment|PROCEDURE: IVF (In Vitro Fertilization) Antagonist Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hippocampal Network Changes Following Mindfulness Training in Tobacco Vaping Adolescents in an Open-label, Pilot Study
Status: RECRUITING
Conditions: Vaping Teens|Healthy Volunteers
Interventions: BEHAVIORAL: Mindfulness-based Stress Reduction (MBSR) Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Carbetocin Versus Ergometrine in the Management of Atonic Post Partum Haemorrhage (PPH) in Women Delivered Vaginally
Status: UNKNOWN
Conditions: Post Partum Hemorrhage
Interventions: DRUG: Carbetocin|DRUG: Ergometrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Study of Immunotherapy Combinations With Chemotherapy in Patients With Gastric or Gastroesophageal Junction (GEJ) Cancers
Status: COMPLETED
Conditions: Gastric Cancer|Cancer of the Stomach|Esophagogastric Junction
Interventions: BIOLOGICAL: BMS-986213|BIOLOGICAL: Nivolumab|DRUG: XELOX|DRUG: FOLFOX|DRUG: SOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Statewide Trial to Compare Three Training Models for Implementing an Evidence-based Treatment (EBT)
Status: COMPLETED
Conditions: Training of Mental Health Professionals|Disruptive Behavior Disorders
Interventions: BEHAVIORAL: Training Models of PCIT|BEHAVIORAL: Training Models of PCIT|BEHAVIORAL: Parent-Child Interaction Therapy (PCIT) Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of AMG 386 to Treat HER2-positive Locally Recurrent or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Breast Neoplasms|Breast Tumors|Cancer|Locally Recurrent and Metastatic Breast Cancer|Metastases|Metastatic Cancer|Oncology|Solid Tumors|Tumors
Interventions: DRUG: AMG 386 30 mg/kg, Paclitaxel and Trastuzumab|DRUG: AMG 386 30 mg/kg, Capecitabine and Lapatinib|DRUG: AMG 386 10 mgkg, Paclitaxel and Trastuzumab|DRUG: AMG 386 10 mg/kg, Capecitabine and Lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Hypoxic Breathwork
Status: NOT_YET_RECRUITING
Conditions: Hypoxic Breathwork With Music and Affirmative Messaging|Hypoxic Breathwork Only|Music and Affirmative Messaging
Interventions: BEHAVIORAL: Hypoxic breathwork plus music and messaging|BEHAVIORAL: Hypoxic breathwork only|BEHAVIORAL: Music and messaging meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Evaluating Combination of Levonorgestrel and Ethinyl Estradiol in Pre-Menstrual Dysphoric Disorder
Status: COMPLETED
Conditions: Premenstrual Syndrome|Menstruation Disturbances
Interventions: DRUG: Levonorgestrel/Ethinyl Estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Topical Desiccant Agent in Association With Manual Debridement in the Treatment of Peri-implant Mucositis
Status: COMPLETED
Conditions: Peri-implant Mucositis
Interventions: DEVICE: topical agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Collateral Damage From the COVID-19 Pandemic Observed in Patients Treated With Intravitreal Injections (IVT) of Anti-angiogenic Agents
Status: COMPLETED
Conditions: Age Related Macular Degeneration|Diabetic Macular Edema|Retinal Vein Occlusion
Interventions: PROCEDURE: Questionnaire|OTHER: Data collection up to 1 year
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Network-based biOmarker Discovery of Neurodegenerative Diseases Using Multimodal Connectivity
Status: RECRUITING
Conditions: Alzheimer Disease, Early Onset|Parkinson Disease
Interventions: DIAGNOSTIC_TEST: fMRI|DIAGNOSTIC_TEST: CONFMEM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neuroinflammation and Alzheimer's Pathology in POCD
Status: UNKNOWN
Conditions: Post-Operative Confusion|Neuroinflammatory Response|Alzheimer Disease
Interventions: BEHAVIORAL: Montreal Cognitive Assessment|BEHAVIORAL: Stroop Test|DIAGNOSTIC_TEST: 4AT Delirium|BEHAVIORAL: Grooved Pegboard|BEHAVIORAL: NACC Cognitive Battery|DIAGNOSTIC_TEST: ERP Testing|DIAGNOSTIC_TEST: Blood Plasma and Serum sampling|DIAGNOSTIC_TEST: Cerebral Spinal Fluid Sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Use of Amantadine in the Prevention of Progression and Treatment of COVID-19 Symptoms
Status: UNKNOWN
Conditions: COVID-19|SARS-CoV-2
Interventions: DRUG: Amantadine Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Salivary C1P and PGE2 Levels in Periodontitis Patients With T2DM and Effect of Non-Surgical Periodontal Treatment
Status: COMPLETED
Conditions: Periodontitis|Type 2 Diabetes
Interventions: PROCEDURE: Non-surgical periodontal treatment|DIAGNOSTIC_TEST: ELISA Test|OTHER: Periodontal Examination|OTHER: Saliva Sample Collection|DIAGNOSTIC_TEST: HbA1c Level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Synergistic Benefits of MCE and BT in Sacroiliac Joint Dysfunction: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Sacroiliac Joint Dysfunction
Interventions: OTHER: Motor Control Exercise|OTHER: Balance Training|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective RCT Of Water Exchange (WE) vs. WE Plus Cap-Assisted Colonoscopy
Status: COMPLETED
Conditions: Unsedated Colonoscopy|Water Exchange Colonoscopy|Cap|Colonoscopy Pain
Interventions: OTHER: Control|DEVICE: Study method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improvement of Reproductive Function in Men With Spinal Cord Injury (SCI)
Status: RECRUITING
Conditions: Infertility, Male
Interventions: DRUG: Probenecid 500 Milligrams (mg)|DRUG: probenecid 250 Milligrams (mg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Total Knee Arthroplasty: Comparison of Fixed and Mobile Bearings
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Total knee arthroplasty: mobile bearing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study: Ulthera® System for the Treatment of Axillary Hyperhidrosis
Status: COMPLETED
Conditions: Hyperhidrosis
Interventions: DEVICE: Ulthera System treatment|DEVICE: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of an Emotional Robot on Quality of Working Life of Caregivers in a Geriatric Unit
Status: UNKNOWN
Conditions: Burnout, Professional|Stress|Anxiety
Interventions: DEVICE: Use of the "PARO" emotional robot
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Support Through Remote Observation and Nutrition Guidance (STRONG) Program for Pancreatic Cancer Patients
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: BEHAVIORAL: Consultations with Moffitt Dietician|BEHAVIORAL: Daily Food Intake Diary with Fitbit Smartphone application|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Breathing Exercises on Pain, Anxiety, Dyspnea, and Insomnia in Patients Undergoing Lung Surgery.
Status: RECRUITING
Conditions: Lung Surgery
Interventions: BEHAVIORAL: Breathing Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Whole Grains, Gastric Emptying and Glycemic Response
Status: COMPLETED
Conditions: Obesity|Diabetes Mellitus, Type 2|Appetitive Behavior
Interventions: OTHER: Cracked whole wheat porridge|OTHER: Semolina wheat porridge|OTHER: Whole wheat flour porridge|OTHER: Refined wheat flour porridge|OTHER: Refined wheat flour porridge,fine bran|OTHER: Refined wheat flour porridge,coarse bran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Study to Evaluate the Effect of Different Doses of UC-II® Supplementation on the Range of Motion & Joint Discomfort in Healthy Subjects
Status: RECRUITING
Conditions: Joint Pain
Interventions: DRUG: Collagen type II (40 mg/day)|DRUG: Collagen type II (80mg/day)|DRUG: Collagen type II (120 mg/day)|DRUG: Glucosamine Hydrochloride with Chondroitin Sulphate (2700 mg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Safety and Efficacy Study to Evaluate AMG 334 in Migraine Prevention
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Placebo|DRUG: Erenumab|DRUG: Erenumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Subcutaneous Zilucoplan in Pediatric Participants With Generalized Myasthenia Gravis
Status: RECRUITING
Conditions: Generalized Myasthenia Gravis
Interventions: DRUG: Zilucoplan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph II Study of Perifosine Plus Gleevec for Patients With GIST
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Perifosine|DRUG: Imatinib Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Operation and Medical Treatment of Endometriosis and Adenomyosis
Status: COMPLETED
Conditions: Endometriosis|Adenomyosis
Interventions: DRUG: Leuprorelin|DEVICE: Levonorgestrel|DRUG: Dienogest|DRUG: Progestins
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevention of Postpartum Haemorrhage With Sublingual Misoprostol or Oxytocin
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Misoprostol|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Space and Interaction Trial: Room Design and Patient-physician Interaction
Status: COMPLETED
Conditions: Internal Medicine Patients|Participating Staff
Interventions: OTHER: Re-designed room|OTHER: Control room
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Recombinant New Coronavirus Vaccine (CHO Cells) to Prevent SARS-CoV-2（COVID-19） Phase I Clinical Trial (3~17 Years Old)
Status: COMPLETED
Conditions: Coronavirus
Interventions: BIOLOGICAL: Recombinant new coronavirus vaccine (CHO cell) group|BIOLOGICAL: Recombinant new coronavirus vaccine (CHO cells) placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: VITamin D and OmegA-3 TriaL (VITAL): Fractures, Vitamin D and Genetic Markers
Status: ACTIVE_NOT_RECRUITING
Conditions: Fractures
Interventions: DIETARY_SUPPLEMENT: Vitamin D3 placebo|DIETARY_SUPPLEMENT: Fish oil placebo|DRUG: omega-3 fatty acids (fish oil)|DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy Of Sodium Glucose Transporter Inhibitor (SGLT2I) In Adult Patients With Congenital Heart Disease
Status: RECRUITING
Conditions: Adult Congenital Heart Disease|Heart Failure
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HDtDCS in Logopenic Variant PPA: Effects on Language and Neural Mechanisms
Status: COMPLETED
Conditions: Primary Progressive Aphasia
Interventions: DEVICE: HD-tDCS|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Venous Thromboembolic Prophylaxis After Trauma: Three Times a Day Unfractionated Heparin Versus Twice a Day Enoxaparin
Status: COMPLETED
Conditions: Venous Thromboembolic Disease|Deep Vein Thrombosis|Pulmonary Embolism
Interventions: DRUG: 5000 Units unfractionated Heparin Q 8 hr|DRUG: 30mg enoxaparin Q12 hr
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of VGL101 in Patients With Adult-Onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia
Status: ACTIVE_NOT_RECRUITING
Conditions: ALSP
Interventions: DRUG: VGL101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EFFECTS OF CARDICHOL, AN HERBAL DIETARY SUPPLEMENT, IN MODERATE HYPERCHOLESTEROLEMIA
Status: UNKNOWN
Conditions: HYPERCHOLESTEROLEMIA
Interventions: DIETARY_SUPPLEMENT: CARDICHOL|DIETARY_SUPPLEMENT: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Use of High Dose Radiation Followed by Chemotherapy and Radiation to Treat Locally Advanced NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer Stage II|Lung Cancer Stage III|Non Small Cell Lung Cancer
Interventions: RADIATION: SBRT|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: cis Platinum|DRUG: Etoposide|RADIATION: IMRT|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of LAVA-051 in Patients With Relapsed/Refractory CLL, MM, or AML
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Multiple Myeloma|Acute Myeloid Leukemia
Interventions: BIOLOGICAL: LAVA-051|BIOLOGICAL: Interleukin 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Shexiang Tongxin Dropping Pills on Microcirculation in Patients With AMI
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Shexiang Tongxin Dropping Pills + routine treatment|PROCEDURE: routine treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Bioavailability of Solid Formulation of GLPG1837 With and Without Food
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 500 mg GLPG1837 as oral suspension|DRUG: 500 mg GLPG1837 as oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of The Pharmacokinetics And Safety Of Ipatasertib In Chinese Participants With Locally Advanced Or Metastatic Solid Tumors.
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Ipatasertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internal Limiting Membrane Peeling-reposition to Treat Idiopathic Macular Holes
Status: COMPLETED
Conditions: Macular Hole|Surgery
Interventions: PROCEDURE: peeling-reposition|PROCEDURE: peeling|DRUG: Brilliant Blue G|OTHER: postoperative posture|DEVICE: Constellation 23-gauge vitrectomy system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kinetics of Inflammation Markers in Maternal Plasma: Study of the Correlation With the Diagnosis of Chorioamnionitis in Women Hospitalized for Spontaneous Rupture of the Fetal Membranes
Status: TERMINATED
Conditions: Patients With Spontaneous Rupture of the Fetal Membranes
Interventions: OTHER: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Study of Anti-Cancer Therapies Targeting the MAPK Pathway in Patients With Hematologic Malignancies
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: ERAS-007|DRUG: ERAS-601|DRUG: Gilteritinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gallium-68 Labeled Pentixafor PET/CT in Adrenal Masses
Status: UNKNOWN
Conditions: Adrenal Mass
Interventions: DIAGNOSTIC_TEST: Gallium-68 Pentixafor PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Study to Evaluate the Pharmacokinetics of BAT2506 vs Simponi® in Healthy Subjects
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: Drug: BAT2506 injection Other Names: Simponi(EU-licensed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Ecallantide for the Acute Treatment of Angiotensin Converting Enzyme Inhibitor Induced Angioedema
Status: UNKNOWN
Conditions: Angioedema
Interventions: DRUG: ecallantide - Kallikrein inhibitor that blocks the production of bradykinin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Expanded Access for LOXO-260 in Participants With Cancer Caused by an Abnormal RET Gene That Did Not Respond/is no Longer Responding to Treatment With a Type of Drug Called a RET Inhibitor
Status: NO_LONGER_AVAILABLE
Conditions: Carcinoma, Non-Small-Cell Lung|Thyroid Neoplasms
Interventions: DRUG: LOXO-260
Study Type: EXPANDED_ACCESS
Clinical trial: Cortisol Regulation in Polycystic Ovary Syndrome (PCOS)
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: pioglitazone|DRUG: metformin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Clinical Study Between Colistin-Tigecycline Combined Therapy Versus Colistin-Meropenem Combined Therapy in Treatment of Blood Stream Infections With Multidrug-Resistant Klebsiella Pneumoniae
Status: UNKNOWN
Conditions: Treatment of Blood Stream Infections Due to Multidrug-Resistant Klebsiella Pneumoniae
Interventions: DRUG: Colistin|DRUG: Meropenem|DRUG: Tigecycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide, Abatacept, and Tacrolimus for the Prevention of GvHD
Status: RECRUITING
Conditions: Graft Vs Host Disease
Interventions: DRUG: Cyclophosphamide|DRUG: Abatacept|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prognostic Evaluation of Changing Endocrine Therapy in Women With Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Anastrozole|DRUG: Tamoxifen|DRUG: Toremifene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Androgen Suppression Plus Radiation Therapy in Treating Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: LHRH agonist|DRUG: antiandrogen|RADIATION: radiation therapy|RADIATION: Brachytherapy boost
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal Progesterone Supplementation in Women With PCOS Undergoing Ovulation Induction With Letrozole
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Progesterone Vaginal Gel 8%|DRUG: Letrozole Oral Tablet|DIAGNOSTIC_TEST: pelvic ultrasound|DRUG: Ovidrel 250 MCG Per 0.5 ML Prefilled Syringe|OTHER: Intrauterine insemination or timed intercourse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Sunitinib in Patients With Renal Cells Carcinoma Metastasic or Locally Avanced in Patients Not Candidates to Curative Previous Nefrectomy
Status: COMPLETED
Conditions: Carcinoma Renal Cells
Interventions: DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 4 Week Study of Elidel (Pimecrolimus) for the Treatment of Seborrheic Dermatitis
Status: COMPLETED
Conditions: Seborrheic Dermatitis
Interventions: DRUG: Elidel|DRUG: Ketoconazole Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CELLO - CLiRpath® Excimer Laser System to Enlarge Lumen Openings
Status: COMPLETED
Conditions: Peripheral Artery Disease
Interventions: DEVICE: CLiRpath Photoablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Evaluate Safety of GR-MD-02 in Subjects With Non-Alcoholic Steatohepatitis (NASH) and Advanced Fibrosis
Status: COMPLETED
Conditions: Non-Alcoholic Steatohepatitis (NASH)
Interventions: DRUG: GR-MD-02|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Effect of Single Oral Dose of MY008211A Tablets on QTc Interval in Healthy Subjects
Status: NOT_YET_RECRUITING
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: MY008211A tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-operative IRX-2 in Early Stage Breast Cancer (ESBC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Neoplasm|Breast Neoplasm, Male|Triple Negative Breast Cancer
Interventions: DRUG: Cyclophosphamide|DRUG: Indomethacin|DRUG: Omeprazole|DIETARY_SUPPLEMENT: Multivitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Strategies for Children With Smith-Magenis Syndrome
Status: COMPLETED
Conditions: Developmental Delay Disorders|Chromosome Deletion|Mental Retardation|Sleep Disorders, Circadian Rhythm|Self Injurious Behavior
Interventions: DRUG: dTR Melatonin (NIH CC PDS)|DEVICE: Phototherapy (Bright Light)|DRUG: Melatonin CR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation the Pharmacokinetics, Safety, Tolerability of TK001 in Patients With Neovascular Age-related Macular Degeneration
Status: UNKNOWN
Conditions: Neovascular Age-related Macular Degeneration
Interventions: BIOLOGICAL: TK001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Marginal Acquisition With Thermacut Bur Vs. Functional Crown Lengthening in Deep Carious Lesions
Status: RECRUITING
Conditions: Deep Caries
Interventions: PROCEDURE: deep marginal acquisition using thermacut bur
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of New Therapeutic Targets to Prevent Collagen Accumulation During Cardiac Fibrosis: Procollagen C-proteinase Enhancers
Status: COMPLETED
Conditions: Valvulopathy|Heart Surgery|Procollagen C-Proteinase Enhancers
Interventions: BIOLOGICAL: Biopsies|BIOLOGICAL: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Combined Contraceptive Vaginal Ring(NuvaRing)in Women With Idiopathic Menorrhagia
Status: COMPLETED
Conditions: Menorrhagia
Interventions: DRUG: NuvaRing|DRUG: Norethisterone Acetate tablets - 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The MUSE Study for Menopausal Arthralgia
Status: RECRUITING
Conditions: Arthralgia|Menopause|Perimenopausal Disorder|Joint Pain|Postmenopausal Disorder
Interventions: DRUG: Menopausal hormone therapy|BEHAVIORAL: Exercise training|COMBINATION_PRODUCT: Menopausal hormone therapy + exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calibration of a Non-invasive Glucose Measurement Device and Assessment of Its Performance in the Hypoglycemic Range in Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DEVICE: P0.3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Study of CyPass Implantation In Patients With Open Angle Glaucoma Refractory to Single or Multi-agent Topical Therapy
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma (POAG)
Interventions: DEVICE: CyPass Micro-Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic Intervention in PCOS
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DIETARY_SUPPLEMENT: Probiotic|DRUG: Metformin Hydrochloride|DIETARY_SUPPLEMENT: Probiotic Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telemonitoring of Patients Admitted in Hospital at Home With Acute Decompensated Heart Failure - Pilot Study
Status: UNKNOWN
Conditions: Heart Failure; With Decompensation|Heart Failure，Congestive|Heart Failure Acute
Interventions: DEVICE: Telemedicine/telemonitoring (TM) suite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Metformin and Gestational Diabetes in High-risk Patients: a RCTs
Status: UNKNOWN
Conditions: Obesity|Polycystic Ovary Syndrome|Gestational Diabetes
Interventions: DRUG: Metformin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Long Term Follow-Up Study of Human Immunodeficiency Virus Type 1 (HIV-1) Positive Patients Who Have Received OZ1 Gene Therapy as Part of a Clinical Trial
Status: COMPLETED
Conditions: HIV-1
Interventions: GENETIC: OZ1 transduced cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lu-PSMA for Oligometastatic Prostate Cancer Treated With STereotactic Ablative Radiotherapy
Status: RECRUITING
Conditions: Oligometastatic Prostate Cancer
Interventions: DRUG: 177Lu-PSMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conventional Hemodialysis Versus Post-Dilution Hemofiltration in Incident RRT
Status: COMPLETED
Conditions: Dialysis; Complications|Hemodialysis Complication|Cerebral Edema|Cognitive Impairment
Interventions: OTHER: Hemofiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cohort Study for Patients Using Fuzeon (Enfuvirtide)
Status: UNKNOWN
Conditions: HIV Infections|Antiretroviral Treatment
Interventions: DRUG: Fuzeon (Enfuvirtide)|PROCEDURE: Laboratory diagnostic (CD4-cells)|PROCEDURE: Laboratory diagnostics (HIV-1 viral load)|DRUG: antiretroviral co-medication beside Fuzeon
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Determine Optimal Absorption of Single Dose Omega-3
Status: COMPLETED
Conditions: Optimal Gastrointestinal Absorption of Omega-3
Interventions: DRUG: Product 1 - AquaCelle Fish Oil Triglyceride|DRUG: Product 2 - AquaCelle Fish Oil Ethyl Ester|DRUG: Product 3 - Standard Fish Oil Triglyceride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Validation of CapsoVision CapsoCam® SV-3 Capsule Endoscopy System
Status: COMPLETED
Conditions: Intestinal Disease|Inflammatory Bowel Diseases|Crohn Disease|Ulcer|Celiac Disease
Interventions: DEVICE: SV-3 Capsule Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of PF-07265807 in Participants With Metastatic Solid Tumors.
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoplasm Metastasis
Interventions: DRUG: PF-07265807|DRUG: Sasanlimab|DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid and Cannabinoid Interactions
Status: COMPLETED
Conditions: Marijuana Usage|Opioid Use
Interventions: DRUG: Vaporized Marijuana|DRUG: Opioid Agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sleeve Gastrectomy Versus Gastric Bypass for Private Pay Patients Seeking Obesity Surgery
Status: WITHDRAWN
Conditions: Morbid Obesity
Interventions: PROCEDURE: Laparoscopic Sleeve Gastrectomy|PROCEDURE: Laparoscopic Gastric Bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Prevention of Epileptic Seizures in Acute intraCerebral Haemorrhage
Status: COMPLETED
Conditions: Acute intraCerebral Haemorrhage
Interventions: DRUG: Lévétiracetam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT