pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Submerged vs. Nonsubmerged Single Laser-microgrooved Dental Implants.
Status: COMPLETED
Conditions: Partially Edentulous Maxilla, Mandible
Interventions: DEVICE: Microgrooved dental implants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Real-time fMRI Neurofeedback and Motor Imagery to Enhance Motor Timing and Precision in Cerebellar Ataxia
Status: COMPLETED
Conditions: Cerebellar Ataxia|Spinocerebellar Ataxias|Cerebellar Degeneration
Interventions: DEVICE: Neurofeedback treatment|BEHAVIORAL: At-home therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Aerobic and Anaerobic Exercise on Oxidative Stress and Cellular Fitness in Healthy Trained Young Men
Status: ENROLLING_BY_INVITATION
Conditions: Health, Subjective
Interventions: OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy
Status: RECRUITING
Conditions: Primary IgA Nephropathy
Interventions: DRUG: LNP023
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 24-Hour Vaginal Dinoprostone Pessary Versus Gel for Labour Induction
Status: COMPLETED
Conditions: Labor, Induced|Cervical Ripening
Interventions: DRUG: Dinoprostone vaginal pessary|DRUG: Dinoprostone vaginal gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Topical Tranexamic Acid and Bacitracin in Dialysis Patients
Status: COMPLETED
Conditions: Arteriovenous Fistula
Interventions: DRUG: Topical Tranexamic Acid 5% with bacitracin|OTHER: Topical Tranexamic Acid 25% with bacitracin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Implementing a Real Time Frequent Admitter Risk Score (FAM-FACE-SG) on Readmission Rates
Status: WITHDRAWN
Conditions: Patient Readmission
Interventions: OTHER: FAMFACESG|OTHER: Control|OTHER: FAMFACESG|OTHER: FAMFACESG|OTHER: FAMFACESG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase I/II Clinical Study of Pralatrexate in Japanese Patients With Relapsed or Refractory Peripheral T-cell Lymphoma
Status: COMPLETED
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: Pralatrexate injection|DIETARY_SUPPLEMENT: Vitamin B12|DIETARY_SUPPLEMENT: Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Riociguat in Patients With Systemic Sclerosis
Status: COMPLETED
Conditions: Scleroderma, Systemic
Interventions: DRUG: Riociguat (Adempas, BAY63-2521)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial (RCT) to Compare the Efficacy of Coban 2 Versus SSB in the Treatment of Venous Leg Ulcers
Status: COMPLETED
Conditions: Venous Ulcer
Interventions: DEVICE: Coban 2|DEVICE: SSB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 5Fr Bipolar Electrode vs. Conical Optical 5Fr Fibers for Dual Wave-length Diode Laser for Hysteroscopic Polypectomy
Status: RECRUITING
Conditions: Endometrial Polyp
Interventions: DEVICE: 5Fr hysteroscopic bipolar electrode or conical optical 5Fr fibers for dual wave-length diode laser
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Annual or Biannual Doses of Moxidectin or Ivermectin for Onchocerciasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Onchocerciasis
Interventions: DRUG: Moxidectin|DRUG: Ivermectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opioids for Refractory Breathlessness in Chronic Obstructive Pulmonary Disease
Status: WITHDRAWN
Conditions: Chronic Obstructive Pulmonary Disease|Dyspnea
Interventions: DRUG: Morphine sulfate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LB-100 in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndromes (MDS)
Status: RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: LB-100
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of AMG 890 in Subjects With Elevated Plasma Lipoprotein(a)
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: AMG 890|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Effects of Intravenous Fluids on Perfusion Index and Pleth Variability Index
Status: COMPLETED
Conditions: Perfusion
Interventions: DRUG: sodium chloride|DRUG: Hydroxyethylstarch|DRUG: Ringer-Lactate Infusion Solution Bag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dexmedetomidine Combined With the Closed Loop of Target Controlled Infusion of Propofol for Anesthesia With Intraoperative Wake up
Status: UNKNOWN
Conditions: Anesthesia; Reaction
Interventions: DRUG: Anesthesia induction,propofol, remifentanil ,cisatracurium|DRUG: Anesthesia maintenance , propofol,remifentanil,cisatracurium|PROCEDURE: Awaken test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: EUS-Elastography and Contrast-Enhanced EUS Diagnostic Accuracy in the Differential Diagnosis of Subepithelial Gastrointestinal Tumors
Status: RECRUITING
Conditions: Gastrointestinal Subepithelial Tumors
Interventions: PROCEDURE: EUS-FNB
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Using Preprocedural Urine NMR(Nuclear Magnetic Resonance) -Based Metabolomics Analysis
Status: COMPLETED
Conditions: Contrast-induced Nephropathy|Coronary Angiography
Interventions: PROCEDURE: Coronary Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Retrospective Analysis Of Progression Free Survival And Overall Survival In A National Cohort Of Patients With Metastatic Renal Cell Carcinoma Treated In Denmark From 2006-2010. DARENCA Study 2.
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: OTHER: Non-interventional
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Personalized Volume-deescalated Elective Nodal Irradiation in Oropharyngeal Head and Neck Squamous Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Oropharynx Cancer
Interventions: RADIATION: De-escalation of irradiated volume
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Bupropion XL 150 mg Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Abrika Bupropion 150 mg XL Tablet, single dose|DRUG: Wellbutrin XL® 150 mg Tablet, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Long-Term Effects of Amantadine in Parkinsonian (AMANDYSK)
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: mantadix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ologen (OculusGen)-Glaucoma and Pterygium Historical Control Study in China Beijing Hospital
Status: COMPLETED
Conditions: Glaucoma|Pterygium
Interventions: DEVICE: OculusGen Biodegradable Collagen Matrix Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Lamotrigine to Reverse Cognitive Impairment in Chronic Corticosteroid-Treated Patients
Status: COMPLETED
Conditions: Memory Impairment Due to Corticosteroid Use|Hypomania Due to Corticosteroid Use|Hippocampal Atrophy Due to Corticosteroid
Interventions: DRUG: Lamotrigine (Drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Clinical Outcome and Cost-effectiveness of Reduced Noradrenaline by Using a Lower Blood Pressure Target in Patients With Cardiogenic Shock From Acute Myocardial Infarction
Status: RECRUITING
Conditions: Cardiogenic Shock|Myocardial Infarction
Interventions: DRUG: Reduced noradrenaline use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment
Status: RECRUITING
Conditions: Electric Stimulation Therapy|Obesity|Weight Loss|Eating
Interventions: DEVICE: Transcranial Direct Current Stimulation (TDCS)|OTHER: Sham/no-stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of a Social Skills Program for Children and Adolescents With ASD
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Adaptation of the Social Adjustment Enhancement Intervention of the UC Davis MIND Institute (Solomon, 2004).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Project 4: Ambulatory Biofeedback and Voice Therapy for Patients With Vocal Hyperfunction
Status: NOT_YET_RECRUITING
Conditions: Voice Disorders|Vocal Fold Polyp|Vocal Nodules in Adults|Muscle Tension Dysphonia
Interventions: DEVICE: Ambulatory Voice Monitoring with Biofeedback (AVM-B)|BEHAVIORAL: Conversation Training Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Blinded, Self-control Trial to Evaluate an Artificial Intelligence Based CAD System for Diabetic Retinography
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DEVICE: DR Grading with CAD|OTHER: DR Grading by expert panel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Caries Prevention Effect of S-PRG Filler Incorporated in Denture Base Resins on Edentulous Elderly People
Status: COMPLETED
Conditions: Dental Caries
Interventions: DEVICE: S-PRG filler|DEVICE: PMMA resin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Hydrogen-rich Water for Non-alchoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: Hydrogen|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: One Plus One Equals Two, Will That do?
Status: COMPLETED
Conditions: Sphincter (Anal); Perineal Rupture, Obstetric|Perineal Tear|Pelvic Floor Disorders|Experience, Life|Second Stage of Labor
Interventions: BEHAVIORAL: Two midwives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Investigating Safety, Tolerability and Efficacy of AZD5363 in Prostate Cancer.
Status: COMPLETED
Conditions: Metastatic Castrate-Resistant Prostate Cancer (mCRPC),|Efficacy,|Safety and Tolerability,|Pharmacokinetics,|Pharmacodynamics,|Tumour Response.
Interventions: DRUG: Intermittent dosing of AZD5363|DRUG: Intermittent dosing of AZD5363|DRUG: Intermittent dosing of AZD5363
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: ON/OFF Stimulation and Reward Motivation in Patients With Deep Brain Stimulators
Status: RECRUITING
Conditions: Obsessive Compulsive Disorder|Major Depressive Disorder|Epilepsy
Interventions: DEVICE: Deep Brain Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Locomotor and Bladder Function in Individuals With Acute Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: COMBINATION_PRODUCT: Epidural stimulation + Stand Training|COMBINATION_PRODUCT: Epidural stimulation + Step Training|COMBINATION_PRODUCT: Epidural stimulation + Bladder Capacity Training|COMBINATION_PRODUCT: Epidural stimulation + Bladder Voiding Efficiency Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Active Search for Pediatric HIV/AIDS (ASPA)
Status: UNKNOWN
Conditions: Pediatric HIV Infection
Interventions: PROCEDURE: targeted Provider-Initiated-Testing and Counseling (tPITC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Ypeginterferon Alfa-2b in HBeAg Positive Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Ypeginterferon alfa-2b|DRUG: Peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Gefitinib Plus Nimotuzumab Versus Gefitinib in Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Gefitinib and Nimotuzumab|DRUG: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IIT Study of M1-c6v1 Combined With SHR-1210 and Apatinib in Patients With HCC
Status: UNKNOWN
Conditions: Advanced/Metastatic Hepatocellular Carcinoma
Interventions: DRUG: Recombinant oncolytic virus M1, anti PD-1 antibody, Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Natural Enzymes Mouthwash: a Randomised Controlled Trial
Status: COMPLETED
Conditions: Xerostomia|Dry Mouth
Interventions: OTHER: Natural enzymes mouthwash|OTHER: Benzydamine mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Atomoxetine for Treating Attention Deficit Hyperactivity Disorder in Young Children
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Atomoxetine|DRUG: Placebo|BEHAVIORAL: Parent Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Fidelity to Family-Based Treatment for Adolescent Anorexia Nervosa
Status: COMPLETED
Conditions: Online Training for Therapists
Interventions: OTHER: Standard FBT training|OTHER: Novel FBT training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pegylated Liposomal Doxorubicin and Carboplatin as First Line Treatment for Patients With Advanced Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: PLD and Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Short-Term Effects of Dry Cupping the Lumbar Paraspinal Muscles in Individuals With Non-specific Low Back Pain
Status: NOT_YET_RECRUITING
Conditions: Non-specific Low Back Pain
Interventions: OTHER: Dry Cupping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of Open-Angle Glaucoma Subjects on One Topical Hypotensive Medication Treated With Two iStents
Status: COMPLETED
Conditions: Subjects With Primary Open-angle Glaucoma (POAG)
Interventions: DEVICE: iStent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiotherapy for Nonmelanoma Skin Cancer
Status: TERMINATED
Conditions: Non-melanoma Skin Cancer
Interventions: RADIATION: 30 Gy in 5 fractions|RADIATION: 40 Gy in 10 fractions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Barbed and Conventional Sutures in Adhesion Formation Following Cesarean Section
Status: UNKNOWN
Conditions: Cesarean Section
Interventions: DEVICE: Barbed suture ( STRATAFIX™ )|DEVICE: Conventional suture (VICRYL™)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Narlaprevir Used in Combination With Ritonavir in Treatment-Naïve and Failed Prior Treatment With Pegylated Interferon/Ribavirin Patients With Chronic Hepatitis C Genotype 1 (PIONEER - Study)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Narlaprevir|DRUG: Ritonavir|DRUG: Placebo Narlaprevir|DRUG: Placebo Ritonavir|DRUG: Pegylated interferon alfa-2a/ Pegylated interferon alfa-2b|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-AmBF3-TATE PET/CT for Imaging NET Patients
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DIAGNOSTIC_TEST: 18F-AmBF3-TATE PET/CT|DIAGNOSTIC_TEST: Routine blood draw
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PCT of Pharmacopuncture for Chronic Neck Pain
Status: NOT_YET_RECRUITING
Conditions: Neck Pain|Chronic Pain
Interventions: PROCEDURE: Pharmacopuncture|PROCEDURE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Description of Characteristics, Such as Age, Previous and Concurrent Treatments, Associated Diseases, of Patients With Asthma Treated With Dupilumab (DUPIXENT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma
Interventions: DRUG: Dupilumab SAR231893
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Anti-HCV Drug (BMS-790052) Combined With Peginterferon and Ribavirin in Patients Who Failed Prior Treatment
Status: COMPLETED
Conditions: Hepatitis C Virus
Interventions: DRUG: BMS-790052|DRUG: BMS-790052|DRUG: Placebo|DRUG: peginterferon alfa-2a|DRUG: ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Alemtuzumab Versus Anti-thymocyte Globulin to Help Prevent Rejection in Kidney and Pancreas Transplantation
Status: COMPLETED
Conditions: Graft Rejection
Interventions: DRUG: Alemtuzumab|DRUG: Anti-Thymocyte Globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Low Dose Continuous Cyclophosphamide vs Standard Doxorubicin in Advanced Sarcoma Elderly Patients
Status: TERMINATED
Conditions: Soft Tissue Sarcoma Adult
Interventions: DRUG: Cyclophosphamide|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Capillary and Venous Whole Blood and Plasma Concentrations of Five Antipsychotics
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Aripiprazole|DRUG: Quetiapine|DRUG: Olanzapine|DRUG: Risperidone|DRUG: Paliperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bendamustine Plus Subcutaneous Rituximab in Patients With Diffuse Large B-cell Lymphoma
Status: UNKNOWN
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: bendamustine, rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EXPLORE DMR: Early Feasibility Study of the PLAR Implant and Delivery System to Treat Degenerative Mitral Regurgitation
Status: NOT_YET_RECRUITING
Conditions: Degenerative Mitral Valve Disease
Interventions: DEVICE: Transcatheter mitral valve repair (PLAR Implant and Delivery System)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Half-dose Ticagrelor Overcomes High-dose Clopidogrel in Acute Coronary Syndrome Patients With High On-Clopidogrel Platelet Reactivity
Status: UNKNOWN
Conditions: Coronary Artery Disease|Clopidogrel, Poor Metabolism of
Interventions: DRUG: Clopidogrel|DRUG: ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Neuromuscular Block With Low Pressure Pneumoperitoneum in Laparoscopic Abdominal Surgeries
Status: RECRUITING
Conditions: Deep Neuromuscular Block|Low Pressure|Pneumoperitoneum|Laparoscopic Abdominal Surgeries
Interventions: OTHER: Deep neuromuscular block|OTHER: Moderate neuromuscular block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Radiation Ablation in Patients With Hypertrophic CardioMyopathy: NIRA-HOCM
Status: UNKNOWN
Conditions: Hypertrophic Cardiomyopathy
Interventions: DEVICE: Stereotactic body radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Energetics and Function in Older Humans
Status: COMPLETED
Conditions: Aging|Erythrocyte Glutathione Deficiency|Muscle Weakness
Interventions: DIETARY_SUPPLEMENT: Cysteine (as n-acetylcysteine) and Glycine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: RADVAX™ for Relapsed/Refractory Non-Hodgkin Lymphoma: A Phase II Trial of Pembrolizumab + Low Dose Radiotherapy
Status: RECRUITING
Conditions: Non Hodgkin Lymphoma
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of an Anterior Quadratus Lumborum Block vs. a TAP-block for Inguinal Hernia Repair
Status: COMPLETED
Conditions: Inguinal Hernia|Pain, Postoperative
Interventions: DRUG: Oksykodonhydroklorid|DRUG: Ondansetron and Droperidol|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lactated Ringer's Solution to Prevent Post-ERCP Pancreatitis
Status: NOT_YET_RECRUITING
Conditions: Post-ERCP Acute Pancreatitis
Interventions: DRUG: Lactated Ringer|DRUG: Normal Saline 0.9% Infusion Solution Bag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Risperidone Compared With Placebo in the Treatment of Psychotic Symptoms in Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Dementia|Alzheimer Disease|Mental Disorders
Interventions: DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin, Irinotecan, and Radiation Therapy in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer That Can Be Removed By Surgery
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: cisplatin|DRUG: irinotecan hydrochloride|PROCEDURE: therapeutic conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Assessment of the SonR Algorithm in the PARADYM RF SonR CRT-D by Echocardiography
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: SonR CRT Optimization 'On'|DEVICE: SonR CRT Optimization 'Off'
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Safety, Tolerability And Pharmacokinetics Of Single Ascending Doses And The Effect Of Food On Oral WCK 4873 In Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: WCK 4873|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Influence of Muscle Relaxation With Rocuronium Bromide During General Anaesthesia on Muscle Trauma and Postoperative Analgetic Consumption in Patients With Total Hip Prosthesis Implantation
Status: COMPLETED
Conditions: Muscle Relaxation|Muscle Trauma|Analgetic Consumption|Total Hip Replacement
Interventions: PROCEDURE: effect of muscle relaxation on muscle trauma, control group without relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Encapsulated Faecal Microbiota Transplantation to Preserve Residual Beta Cell Function in Type 1 Diabetes Mellitus
Status: UNKNOWN
Conditions: Type 1 Diabetes
Interventions: OTHER: encapsulated autologous fecal microbiota transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Neural Therapy Effect on Long Term Postoperative Discomforts in Patients Who Undergo Bilateral Tubal Ligation
Status: COMPLETED
Conditions: Pain, Postoperative|Neural Therapy of Huneke|Dysmenorrhea|Dyspareunia|Sterilization, Tubal
Interventions: PROCEDURE: Neural Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of UVB Phototherapy With Microneedling and Circled Needing in Vitiligo Patients
Status: COMPLETED
Conditions: Brief Description of Focus of Study Instead
Interventions: DEVICE: Surrounding needling+ phototherapy|DEVICE: phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of olmesaRtan on Walking distancE and quaLIty of lifE in Peripheral Artery Disease Patients With Hypertension Treated For Intermittent Claudication (RELIEF)
Status: TERMINATED
Conditions: Peripheral Artery Disease With Intermittent Claudication
Interventions: DRUG: Olmesartan|DRUG: other anti-hypertensive drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted Therapy of Bronchiolitis Obliterans Syndrome
Status: COMPLETED
Conditions: Bronchiolitis Obliterans
Interventions: DRUG: fluticasone propionate|DRUG: montelukast sodium|DRUG: azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Ritual Epost Postnatal Multivitamins During the Postpartum Period
Status: RECRUITING
Conditions: Lactation Disorder - Postpartum Condition or Complication|Nutrition, Healthy
Interventions: DIETARY_SUPPLEMENT: Ritual Epre Multimineral-Vitamin Supplement|DIETARY_SUPPLEMENT: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Clinical Study of CWP232291 in Acute Myeloid Leukemia Patients
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Chronic Myelomonocytic Leukemia|Myelodysplastic Syndrome|Myelofibrosis
Interventions: DRUG: CWP232291
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Very Small Embryonic-like Stem Cells for Ovary
Status: WITHDRAWN
Conditions: Stem Cell Transplant Complications|Premature Ovarian Failure
Interventions: BIOLOGICAL: very small embryonic-like stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Locally Applied Antibiotics for Infection Prophylaxis in Treatment of Open Fractures
Status: TERMINATED
Conditions: Fractures, Open
Interventions: DRUG: Tobramycin|OTHER: Placebo: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrent Nimotuzumab Versus Cisplatin With Radiotherapy for Locoregionally Advanced NPC
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: TPF neoadjuvant chemotherapy|DRUG: Concurrent chemotherapy with cisplatin during radiotherapy|DRUG: Concurrent nimotuzumab during radiotherapy|RADIATION: Radical radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of the Poly(ADP-Ribose) Polymerase Inhibitor E7016 in Combination With Temozolomide in Subjects With Wild Type BRAF Stage IV or Unresectable Stage III Melanoma
Status: TERMINATED
Conditions: Wild Type BRAF Stage IV Melanoma|Unresectable Stage III Melanoma
Interventions: DRUG: TMZ|DRUG: E7016
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Modafinil and Methylphenidate in Treatment of Excessive Daytime Sleepiness in Patients With Parkinson's Disease
Status: WITHDRAWN
Conditions: Parkinson's Disease
Interventions: DRUG: modafinil|DRUG: methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantra® System With the QStat® Cartridge in Trauma
Status: COMPLETED
Conditions: Trauma|Coagulation Defect; Bleeding
Interventions: DIAGNOSTIC_TEST: Quantra System with the QStat Cartridge|DIAGNOSTIC_TEST: Standard Laboratory Tests
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Calcipotriol Plus Hydrocortisone Ointment on the Adrenal Hormone Balance and Calcium Metabolism in Patients With Psoriasis Vulgaris on the Face and Skin Folds
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Calcipotriol plus hydrocortisone (LEO 80190)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Nerve Block and Topiramate in the Treatment of Medication Overuse Headaches
Status: COMPLETED
Conditions: Medication Overuse Headache|Chronic Migraine, Headache
Interventions: DRUG: Topamax|PROCEDURE: Greater Occipital Nerve Block + Supratrochlear Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effects of Balance Training on Balance and Functional Status Patients With Total Hip Arthroplasty
Status: COMPLETED
Conditions: Arthroplasty Complications|Physical Disability|Osteoarthritis, Hip
Interventions: OTHER: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Blood Levels and Effects of AUT00201 in Patients With MEAK
Status: COMPLETED
Conditions: Myoclonus Epilepsies, Progressive
Interventions: DRUG: AUT00201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing Traditional and Biofeedback Telepractice Treatment for Residual Speech Errors
Status: COMPLETED
Conditions: Speech Sound Disorder
Interventions: BEHAVIORAL: Visual-acoustic biofeedback|BEHAVIORAL: Motor-based treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Distraction for Dental Anxiety (RCT)
Status: RECRUITING
Conditions: Dental Anxiety|Dental Phobia|Dental Trauma|Dental Diseases
Interventions: DEVICE: Virtual Reality Distraction|DEVICE: Dental Clinic's Standard Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ZD1839 With Hypofractionated Radiation Therapy With an Immobilization Device for Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Carcinoma (NSCLC)
Interventions: DRUG: ZD1839 (Iressa)|RADIATION: Thoracic Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluorescent Imaging of Nerves With Illuminare-1 During Surgery
Status: RECRUITING
Conditions: Prostate Adenocarcinoma
Interventions: DRUG: Illuminare-1|DEVICE: Karl Storz D-Light C photodynamic diagnostic (PDD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Analyze Lateralized Models and Medializations of Inverted Arthroplasty.
Status: RECRUITING
Conditions: Rotator Cuff Arthropathy|Glenohumeral Osteoarthritis
Interventions: PROCEDURE: reverse shoulder arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pragmatic INitiative for LDL-C Management by a CLinical Pharmacist-Led Team Among Atherosclerotic CardiovascUlar DisEase Patients
Status: NOT_YET_RECRUITING
Conditions: Atherosclerotic Cardiovascular Disease
Interventions: OTHER: Clinical Pharmacy Team|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A 6-month Study to Evaluate Sulforaphane add-on Effects in Treatment of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DIETARY_SUPPLEMENT: sulforaphane|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minocycline for HIV+ Cognitive Impairment in Uganda
Status: TERMINATED
Conditions: HIV-associated Cognitive Impairment|HIV Infections
Interventions: DRUG: minocycline|DRUG: minocycline placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of tDCS in the Preoperative Period of Hallux Valgus Surgical Treatment
Status: COMPLETED
Conditions: Chronic Pain|Hallux Valgus
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TH1902 in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor|TNBC - Triple-Negative Breast Cancer|Hormone Receptor-positive Breast Cancer|Epithelial Ovarian Cancer|Endometrial Cancer|Cutaneous Melanoma|Thyroid Cancer|Small-cell Lung Cancer|Prostate Cancer|SORT1+ Cancers
Interventions: DRUG: TH1902
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Of CP-690,550 In Patients With Impaired Renal Function
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: CP-690,550|DRUG: CP-690,550|DRUG: CP-690,550|DRUG: CP-690,550
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Prospective Investigation of the Risks of Opioid Misuse, Abuse, and Addiction Among Patients Treated With Opioids for the Treatment of Chronic Pain
Status: UNKNOWN
Conditions: Opioid-Related Disorders|Opiate Addiction|Narcotic Abuse|Drug Abuse
Interventions: OTHER: Observation Only
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High-Intensity Focused Ultrasound Therapy in Treating Patients With Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: OTHER: questionnaire administration|PROCEDURE: high-intensity focused ultrasound ablation|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Venavine Intensive® in the Treatment of Symptoms Associated With Chronic Venous Insufficiency
Status: COMPLETED
Conditions: Venous Insufficiency
Interventions: OTHER: Gelatine capsule|OTHER: Venavine Intensive®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROSENIOR. Prevention of Pressure Ulcers, Malnutrition, Poor Oral Health and Falls Among Older Persons Receiving Municipal Health Care and Are Registered in the Quality Registry Senior Alert
Status: RECRUITING
Conditions: Fall|Pressure Ulcer|Malnutrition|Oral Health
Interventions: BEHAVIORAL: Care process for assessements of risks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Remineralization of Molar Incisor Hypomineralization (MIH) With a Hydroxyapatite Toothpaste
Status: COMPLETED
Conditions: Molar Incisor Hypomineralization
Interventions: OTHER: Hydroxyapatite toothpaste|OTHER: Sodium Fluoride Toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: SAFIR-PI3K A Phase II Randomized Maintenance Trial Comparing Alpelisib and Fulvestrant Versus Chemotherapy in PIK3CA Mutated Advanced Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer, PI3K, Alpelisib
Interventions: DRUG: Alpelisib|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultra-long Acting Bronchodilator Therapy in Smoking Asthmatics
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: olodaterol hydrochloride 2.5mcg, tiotropium bromide 2.5mcg|DRUG: olodaterol 2.5 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Bioavailability of Diclofenac in a Combination Product (Diclofenac 2% + Capsaicin 0.075% Topical Gel) With Two Diclofenac Only Products, Diclofenac Mono Gel 2% and Voltarol® 12 Hour Emulgel 2.32% Gel, in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Diclofenac Sodium|DRUG: Diclofenac & Capsaicin|DRUG: Diclofenac Sodium Topical Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intracorporeal vs. Extracorporeal Anastomosis in Patients Undergoing Laparoscopic Right Hemicolectomy for Colonic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colon Cancer
Interventions: PROCEDURE: Extracorporeal anastomosis|PROCEDURE: Intracorporeal anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Potential Mechanisms for Intussusception After Rotavirus Vaccine-Pilot Study
Status: COMPLETED
Conditions: Intussusception|Rotavirus Infections
Interventions: DRUG: Rotarix®,|DRUG: Rotarix®, with other routine vaccines|DRUG: RotaTeq®,|DRUG: RotaTeq®, with other routine vaccines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Other Hematologic or Metabolic Diseases
Status: COMPLETED
Conditions: Graft Versus Host Disease|Leukemia|Myelodysplastic Syndromes|Thymic Carcinoma
Interventions: BIOLOGICAL: anti-thymocyte globulin|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: melphalan|DRUG: methylprednisolone|PROCEDURE: umbilical cord blood transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Impact of Health Literacy on Outcomes and Effectiveness of Shared Decision Making Programs in Patients With Chronic Diseases
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: BEHAVIORAL: Educational Intervention - Text plus DVD/VHS|BEHAVIORAL: Educational Intervention - Text Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) Using Paclitaxel in Gastric Cancer Patients With Peritoneal Metastasis
Status: UNKNOWN
Conditions: Stomach Neoplasm|Peritoneal Metastases
Interventions: PROCEDURE: Pressurized Intraperitoneal Aerosol Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First Human Trial of Targeting MDM2/MDMX PET Imaging
Status: NOT_YET_RECRUITING
Conditions: MDM2/MDMX Gene Mutation|Nuclear Medicine|Positron Emission Tomography Imaing
Interventions: DRUG: [68Ga] MDM2/MDMX Peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dupilumab in the Treatment of Pediatric Alopecia Areata
Status: RECRUITING
Conditions: Alopecia Areata
Interventions: DRUG: Dupilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of ACH-3102 and Simeprevir on AL-335 Pharmacokinetics in Healthy Volunteers
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: AL-335|DRUG: ACH-3102|DRUG: Simeprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Re-biopsy Specimens in Advanced NSCLC With Acquired Resistance of EGFR-TKI Targeted Therapy
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DEVICE: Miseq sequencer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-64140284 in Healthy Participants
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: JNJ-64140284 0.1 mg|DRUG: JNJ-64140284 0.5 mg|DRUG: JNJ-64140284 2.5 mg|DRUG: JNJ-64140284 10 mg|DRUG: JNJ-64140284 50 mg|DRUG: JNJ-64140284 150 mg|DRUG: JNJ-64140284 (dose to be determined [TBD])|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Inhaled Corticosteroids: Effect on Intraocular Pressure in Patients With Controlled Glaucoma
Status: COMPLETED
Conditions: Ocular Hypertension|Glaucoma, Open-Angle
Interventions: DRUG: Fluticasone propionate inhaler|DRUG: Saline placebo inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Tagraxofusp in Patients With CD123+ or With BPDCN-IPh-like Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: tagraxofusp
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-shock Cardiopulmonary Resuscitation to Patients With Out-of-hospital Resuscitation, A Randomised Clinical Trial
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: OTHER: cardiopulmonary resuscitation|OTHER: Rhythm analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT