pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of Milnacipran in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Milnacipran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Large Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: carboplatin|DRUG: etoposide|DRUG: ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Rapid-infusion Isatuximab in Relapsed/Refractory Multiple Myeloma
Status: WITHDRAWN
Conditions: Relapsed Multiple Myeloma|Refractory Multiple Myeloma
Interventions: BIOLOGICAL: Rapid Infusion Isatuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dapagliflozin on Hormonal Glucose Homeostasis in Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Forxiga 10mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Rituximab for Prevention of Rejection After Renal Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Rituximab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Pressure Ulcers With Repositioning Frequency and Precipitating Factors
Status: COMPLETED
Conditions: Pressure Ulcer
Interventions: OTHER: 2 hour repositioning|OTHER: 3 hour repositioning|OTHER: 4 hour repositioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Booster Dose of HCG for Unruptured Follicle in Non IVF/ICSI Cycles
Status: COMPLETED
Conditions: LUF - Luteinised Unruptured Follicle Syndrome
Interventions: DRUG: hCG|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of a Home-based Exercise Intervention for Patients With Acute Myeloid Leukaemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Exercise|Fatigue|Quality of Life
Interventions: BEHAVIORAL: Home-based exercise program|BEHAVIORAL: Wait list
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of McCoy Laryngoscope and C-MAC D-blade Video Laryngoscope in Obese Patients
Status: COMPLETED
Conditions: Obesity
Interventions: DEVICE: McCoy laryngoscope|DEVICE: C-MAC D-blade video laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Disitamab Vedotin in Previously Treated Solid Tumors That Express HER2
Status: RECRUITING
Conditions: Carcinoma, Squamous Cell of Head and Neck|Carcinoma, Non-Small-Cell Lung|Ovarian Neoplasms|Endometrial Neoplasms
Interventions: DRUG: disitamab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiotherapy as a Complimentary Treatment in Reducing Viral-Load, Complications, Death, Expedite Discharge and Improve Quality of Life, Exercise Endurance and Capacity in Stroke Survivors With CoViD-19: A Clinical-Controlled Study
Status: UNKNOWN
Conditions: Corona Virus Infection|Stroke
Interventions: OTHER: Rehabilitation exercise protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Controlling Orthostatic Hypotension in People With Cervical Spinal Cord Injury
Status: ENROLLING_BY_INVITATION
Conditions: Spinal Cord Injury Cervical|Hypotension, Orthostatic
Interventions: DEVICE: Functional electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT of CBT Combined With D-Cycloserine for Treating PTSD
Status: UNKNOWN
Conditions: Post-Traumatic Stress Disorder
Interventions: DRUG: D-cycloserine|BEHAVIORAL: Cognitive-Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Neulasta-controlled Trial of F-627 in Women With Breast Cancer Receiving Myelotoxic Chemotherapy
Status: COMPLETED
Conditions: Breast Cancer|Neutropenia
Interventions: DRUG: F-627|DRUG: Neulasta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Clinical and Radiographic Assessment on New Platform-switched Laser Lok Implants
Status: UNKNOWN
Conditions: Preserve Crestal Bone Level and Gingival Margin Around Dental Implants
Interventions: DEVICE: platform-switch tapered internal implants
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Metastatic Colorectal Adenocarcinoma
Status: TERMINATED
Conditions: Metastatic Colorectal Adenocarcinoma
Interventions: DRUG: Gemcitabine|DRUG: Docetaxel|DRUG: Filgrastim or Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for the Assessment of Delayed Antibiotic Treatment Strategies
Status: COMPLETED
Conditions: Pharyngitis|Acute Tonsillitis|Rhinosinusitis|Acute Bronchitis|Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Antibiotic prescription strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Chlorhexidine Impregnated Dressing and Standard Dressing
Status: COMPLETED
Conditions: Catheter-Related Infections
Interventions: OTHER: Standard dressing|OTHER: Chlorhexidine gluconate -impregnated dressing group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acute Intermittent Hypoxia and Breathing in Neuromuscular Disease
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis (ALS)|Neuromuscular Diseases
Interventions: OTHER: Acute Intermittent Hypoxia|OTHER: Sham Acute Intermittent Hypoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pediatric Kidney Transplant Without Calcineurin Inhibitors
Status: COMPLETED
Conditions: End-Stage Renal Disease
Interventions: DRUG: Daclizumab|DRUG: Methylprednisolone/prednisone|DRUG: Mycophenolate mofetil|DRUG: Sirolimus|DRUG: Bactrim|DRUG: Ganciclovir|DRUG: Lipitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Anti-Epidermal Growth Factor Receptor (EGFr) Antibody, Cetuximab, in Combination With Gemcitabine/Carboplatin in Patients With Stage IV Lung Cancer
Status: COMPLETED
Conditions: Stage IV Non-Small Cell Lung Cancer
Interventions: DRUG: Cetuximab in combination with Carboplatin/Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thorough QT Study to Evaluate the Effects of BI 207127 (Deleobuvir) Combined With Faldaprevir on Cardiac Safety Parameters in Healthy Subjects.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 207127|DRUG: BI 207127 placebo|DRUG: Faldaprevir placebo|DRUG: Faldaprevir|DRUG: Moxifloxacin (Avalox®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Carbetocin Versus Oxytocin for the Prevention of Postpartum Hemorrhage in Emergency Caesarean Delivery
Status: COMPLETED
Conditions: Postpartum Hemorrhage (Primary)
Interventions: DRUG: Carbetocin|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Omega 3 as an Immunomodulator Adjunct to Periodontal Debridement
Status: COMPLETED
Conditions: Periodontitis
Interventions: OTHER: Lactose tab|DRUG: Omega 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Effects on Microelectrode Recording in Deep Brain Stimulation
Status: WITHDRAWN
Conditions: Parkinson's Disease|Essential Tremor|Dystonia
Interventions: DRUG: Dexmedetomidine Hydrochloride Infusion|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use Of A Response-Adapted Ruxolitinib-Containing Regimen For The Treatment Of Hemophagocytic Lymphohistiocytosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemophagocytic Lymphohistiocytosis
Interventions: DRUG: Ruxolitinib|DRUG: Dexamethasone|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate Safety of Gusacitinib in Patients With Systemic Lupus Erythematosus (SLE) or Lupus
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Gusacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of SmofKabiven Extra Nitrogen for Parenteral Nutrition in Patients Receiving Intensive Care
Status: COMPLETED
Conditions: Nutrition Therapy|Critical Illness
Interventions: DRUG: SmofKabiven extra Nitrogen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Liposomal Bupivacaine With or Without Hydromorphone for the Improvement of Pain Control After Laparotomy in Patients With Gynecological Malignancies
Status: COMPLETED
Conditions: Malignant Female Reproductive System Neoplasm
Interventions: DRUG: Hydromorphone|PROCEDURE: Laparotomy|DRUG: Liposomal Bupivacaine|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Relevance of Monitoring Blood and Salivar Levels of Drugs Used in Rheumatic Autoimmune Diseases
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus (SLE)|Juvenile SLE|Cutaneous Lupus
Interventions: DRUG: Thalidomide|DRUG: Hydroxychloroquine reduced|DRUG: standard dose of HCQ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Two Doses of Oral Valacyclovir in Immunocompromised Patients With Uncomplicated Herpes Zoster
Status: COMPLETED
Conditions: Herpes Zoster|Immunologic Deficiency Syndromes
Interventions: DRUG: Valacyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Test an Acceptance-based Therapy Program Among Adolescent Girls With Overweight/Obesity
Status: COMPLETED
Conditions: Weight Loss|Obesity|Overweight
Interventions: BEHAVIORAL: ABT Weight Loss Intervention|OTHER: Enhanced Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy & Tolerability Of PEG 4000 Versus PEG 3350+ Electrolytes for Pediatric Fecal Disimpaction
Status: NOT_YET_RECRUITING
Conditions: Functional Constipation|Fecal Impaction|Constipation - Functional|Constipation Chronic Idiopathic|Pediatric Functional Constipation
Interventions: DRUG: Administration of Polyethylene Glycol (PEG) 4000 as per treatment allocation to participants|DRUG: Administration of Polyethylene Glycol (PEG) 3350 + Electrolyte as per treatment allocation to participants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study to Standard Triple Therapy With Tegoprazan(by Dose) in H. Pylori Positive Patients
Status: RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Tegoprazan 50 mg Triple Therapy|DRUG: Tegoprazan 100 mg Triple Therapy|DRUG: Lansoprazole Triple Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Of Coughing and Active Cycle of Breathing Technique to Improve Pulmonary Functions in Post-Surgical Patients
Status: RECRUITING
Conditions: Post Surgical
Interventions: BEHAVIORAL: Active Cycle of Breathing|DIAGNOSTIC_TEST: Coughing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Pregabalin and Dexamethasone on Acute and Chronic Pain After Lumbar Spinal Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Pregabalin|DRUG: dexamethasone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of TAK-861in People With Narcolepsy Type 1
Status: NOT_YET_RECRUITING
Conditions: Narcolepsy Type 1
Interventions: DRUG: TAK-861|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nicotine Patch Pretreatment for Smoking Cessation in PTSD
Status: COMPLETED
Conditions: Stress Disorders, Posttraumatic|Tobacco Use Disorder
Interventions: DRUG: Nicotine|BEHAVIORAL: Cognitive Behavioral Therapy for Smoking Cessation|DRUG: Bupropion Sustained Release (SR)|DRUG: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Home Testing of Day and Night Closed Loop With Pump Suspend Feature
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 1|Glucose Metabolism Disorders|Endocrine System Diseases|Autoimmune Diseases
Interventions: DEVICE: FlorenceM|DEVICE: Medtronic insulin pump 640G
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Free Fistuloplasty is the Way Forward
Status: RECRUITING
Conditions: Fistulas Arteriovenous
Interventions: PROCEDURE: Ultrasound-guided fistuloplasty|PROCEDURE: Fluoroscopy-guided fistuloplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Immunogenicity and Safety of Whole-Cell Pertussis Containing Vaccine Administered Concomitantly With RotaTeq™ (V260) or Rotarix™ (V260-036)(WITHDRAWN)
Status: WITHDRAWN
Conditions: Rotavirus Gastroenteritis|Diphtheria|Tetanus|Pertussis
Interventions: BIOLOGICAL: Rotavirus Vaccine, Live, Oral, Pentavalent|BIOLOGICAL: Comparator: Rotarix™ administered concomitantly with Tritanrix™ HepB (DTwP)|BIOLOGICAL: Comparator: RotaTeq™ administered concomitantly with INFANRIX™ (DTaP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioavailability of Oral BIRB 796 BS Tablets With and Without Administration of Oral Pantoprazole in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: BIBR 796 BS|DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Furmonertinib as Perioperation Therapy in Stage IIIA-IIIB (N1-N2) Resectable EGFR Mutated Lung Adenocarcinoma (FRONT)
Status: NOT_YET_RECRUITING
Conditions: Lung Adenocarcinoma
Interventions: DRUG: Furmonertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of tDCS to Enhance Auditory Rehabilitation in Cochlear Implant Recipients
Status: ACTIVE_NOT_RECRUITING
Conditions: Hearing Loss
Interventions: DEVICE: Transcranial Direct Stimulation|OTHER: Auditory Training Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Study of TQH2929 Injection in Treatment With Generalized Pustular Psoriasis (GPP)
Status: RECRUITING
Conditions: Generalized Pustular Psoriasis
Interventions: DRUG: TQH2929 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Effect of No-touch Harvesting Technique in OPCABG
Status: UNKNOWN
Conditions: Coronary Artery Disease|Graft Failure
Interventions: PROCEDURE: Conventional vein harvesting technique|PROCEDURE: no-touch vein harvesting technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Brain Metastases Research Platform to Tackle the Challenge of CNS Metastases in Solid Tumours
Status: RECRUITING
Conditions: CNS Metastases
Interventions: OTHER: Samples collection: Plasma|OTHER: Samples collection: CSF|OTHER: Samples collection: Non-CNS Metastatic Tumour Tissue|OTHER: Brain MRI|OTHER: Samples collection: Serum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: New Prospective Expanded German Registry of Incidental Gallbladder Carcinoma (PERSUASION)- a Permanent Platform Including All Kind of Biliary Tract Cancers (BTC)
Status: RECRUITING
Conditions: Biliary Tract Cancer|Neoadjuvant, Adjuvant and 1st Line
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neuroinflammatory and Neurocognitive Effects of Spinal vs. Inhalational Anesthesia for Elective Surgery in Infants
Status: WITHDRAWN
Conditions: Inguinal Hernia
Interventions: DRUG: Spinal Anesthesia (bupivacaine)|DRUG: General Anesthesia (isoflurane)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of MicroRNA in the Diagnosis, Prognosis and Response to Treatment in Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer Stage III|Pancreatic Cancer Stage IV|Pancreatic Ductal Adenocarcinoma|Pancreatic Neoplasms
Interventions: PROCEDURE: Blood draw
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Use of Extended Release Alprazolam in the Treatment of Adolescents With Panic Disorder
Status: TERMINATED
Conditions: Panic Disorder
Interventions: OTHER: placebo|DRUG: alprazolam XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Vein Isolation Vs SHAM-pulmonary Vein Isolation for Symptomatic Relief in Patients with AF
Status: RECRUITING
Conditions: Atrial Fibrillation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thoracic Epidural Analgesia Versus Rectus Sheath Block Versus Surgeon Infiltration With Liposomal Bupivacaine or Standard Bupivacaine for Post-Operative Pain Control After Cystectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Cystectomy
Interventions: DRUG: epidural bupivacaine 0.05%|DRUG: Liposomal bupivacaine|DRUG: bupivacaine 0.125%|DRUG: bupivacaine 0.5%|DRUG: /hydromorphone 0.05mg/ml|DRUG: injectable saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Lung Function Based on Electrical Impedance Tomography and CT Lung Volume in Patients With Rib Fractures
Status: UNKNOWN
Conditions: Rib Fractures
Interventions: DEVICE: Electrical impedance tomography system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of Different Doses and Routes of Exogenous Progesterone Administration on Endometrial Receptivity Parameters
Status: RECRUITING
Conditions: Infertility, Female|ENDOMETRIAL RECEPTIVITY
Interventions: DRUG: Progesterone|OTHER: Artificial Cycle (no intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug /Cue Interactions In Alcohol-Tobacco Comorbidity
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: BEHAVIORAL: Tobacco|OTHER: Alcoholic Beverage|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Subjects With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression
Status: RECRUITING
Conditions: Solid Tumor, Adult|Solid Tumor|Pancreatic Cancer|Pancreatic Neoplasms|Pancreas Cancer|Non Small Cell Lung Cancer|Non Small Cell Lung Cancer Recurrent|Non-Small Cell Squamous Lung Cancer|NSCLC|NSCLC, Recurrent|Colorectal Cancer|Colorectal Neoplasms|Colorectal Adenocarcinoma|CRC|Colorectal Cancer Metastatic|Cancer
Interventions: BIOLOGICAL: A2B530|DIAGNOSTIC_TEST: xT-Onco with HLA-LOH Assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clofarabine or High-Dose Cytarabine and Pegaspargase in Children With ALL
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia
Interventions: DRUG: Amsacrine|DRUG: Clofarabine|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Daunorubicin hydrochloride|DRUG: Dexamethasone|DRUG: Doxorubicin hydrochloride|DRUG: Etoposide phosphate|DRUG: Mercaptopurine|DRUG: Methotrexate|DRUG: Methylprednisolone|DRUG: Pegaspargase|DRUG: Thioguanine|DRUG: Vincristine sulfate|RADIATION: Whole-brain radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combinatorial Therapy for Peristent Type 2 Diabetes After Gastric Banding
Status: TERMINATED
Conditions: Type 2 Diabetes|Gastric Banding
Interventions: DRUG: Liraglutide|DRUG: Orlistat|DRUG: Liraglutide + Orlistat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pregnancy and Neonatal Outcomes Following Antenatal Exposure to Raltegravir: a Pooled Analysis From the European Pregnancy and Paediatric Infections Cohort Collaboration (EPPICC)
Status: RECRUITING
Conditions: HIV Infections
Interventions: DRUG: Raltegravir
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of the Use of Remote Monitoring in the Follow-up of the Renal Transplant Patient.
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Transplantation
Interventions: OTHER: Ap'Telecare|OTHER: traditional schedule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of Mulstidisciplinary Medication Assessment Review in Surgery Departments
Status: RECRUITING
Conditions: Chronic Disease
Interventions: OTHER: Mutlidisciplinary medication Review (MMR)|OTHER: Mutlidisciplinary medication Review (MMR) with community pharmacist follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase I Trial to Determine the Dose and Evaluate the PK of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors
Status: NOT_YET_RECRUITING
Conditions: NET|Lymphoma|Solid Tumor, Childhood|Somatostatin Receptor Positive|CNS Tumor
Interventions: DRUG: Lutetium Lu 177-Edotreotide|OTHER: Amino Acid Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NIDEK Gonioscope GS-1 for Glaucoma
Status: COMPLETED
Conditions: Glaucoma
Interventions: OTHER: NIDEK Gonioscope GS-1|OTHER: Standard Digital Gonioscopic Images
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bevacizumab and Cediranib Maleate in Treating Patients With Metastatic or Unresectable Solid Tumor, Lymphoma, Intracranial Glioblastoma, Gliosarcoma or Anaplastic Astrocytoma
Status: COMPLETED
Conditions: Adult Grade III Lymphomatoid Granulomatosis|Adult Nasal Type Extranodal NK/T-cell Lymphoma|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Childhood Burkitt Lymphoma|Childhood Diffuse Large Cell Lymphoma|Childhood Grade III Lymphomatoid Granulomatosis|Childhood Immunoblastic Large Cell Lymphoma|Childhood Nasal Type Extranodal NK/T-cell Lymphoma|Cutaneous B-cell Non-Hodgkin Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Hepatosplenic T-cell Lymphoma|Intraocular Lymphoma|Nodal Marginal Zone B-cell Lymphoma|Noncutaneous Extranodal Lymphoma|Peripheral T-cell Lymphoma|Progressive Hairy Cell Leukemia, Initial Treatment|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Childhood Anaplastic Large Cell Lymphoma|Recurrent Childhood Large Cell Lymphoma|Recurrent Childhood Lymphoblastic Lymphoma|Recurrent Childhood Small Noncleaved Cell Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent/Refractory Childhood Hodgkin Lymphoma|Refractory Hairy Cell Leukemia|Small Intestine Lymphoma|Splenic Marginal Zone Lymphoma|Stage IV Adult Burkitt Lymphoma|Stage IV Adult Diffuse Large Cell Lymphoma|Stage IV Adult Diffuse Mixed Cell Lymphoma|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma|Stage IV Adult Hodgkin Lymphoma|Stage IV Adult Immunoblastic Large Cell Lymphoma|Stage IV Adult Lymphoblastic Lymphoma|Stage IV Adult T-cell Leukemia/Lymphoma|Stage IV Childhood Anaplastic Large Cell Lymphoma|Stage IV Childhood Hodgkin Lymphoma|Stage IV Childhood Large Cell Lymphoma|Stage IV Childhood Lymphoblastic Lymphoma|Stage IV Childhood Small Noncleaved Cell Lymphoma|Stage IV Grade 1 Follicular Lymphoma|Stage IV Grade 2 Follicular Lymphoma|Stage IV Grade 3 Follicular Lymphoma|Stage IV Mantle Cell Lymphoma|Stage IVA Mycosis Fungoides/Sezary Syndrome|Stage IVB Mycosis Fungoides/Sezary Syndrome|T-cell Large Granular Lymphocyte Leukemia|Testicular Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific|Unspecified Childhood Solid Tumor, Protocol Specific|Waldenström Macroglobulinemia
Interventions: BIOLOGICAL: bevacizumab|DRUG: cediranib maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation and Pharmacokinetic Study of Paclitaxel Liposome Injection in Treating Patients With Advanced Solid Tumor After Failure From Conventional Treatments
Status: UNKNOWN
Conditions: Solid Tumors
Interventions: DRUG: Paclitaxel liposome injection|DRUG: Paclitaxel injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Ovulation in Obese Women
Status: RECRUITING
Conditions: Pregnancy Prevention
Interventions: DRUG: Levonorgestrel 0.15 milligram|DRUG: Meloxicam 15 milligram|OTHER: calcium carbonate 750 milligram
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Stepped Care for Youth Living With HIV
Status: COMPLETED
Conditions: HIV|Mental Health|Illicit Substance Use|Sexually Transmitted Infections (STI)
Interventions: BEHAVIORAL: Level 1|BEHAVIORAL: Level 2|BEHAVIORAL: Level 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Fine Needle Aspiration to Measure Hepatic Vaniprevir (MK-7009) Concentrations in Participants With Chronic Hepatitis C (MK-7009-048)
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Vaniprevir 600 mg|BIOLOGICAL: Peg-IFN alfa-2b|BIOLOGICAL: Ribavirin|PROCEDURE: Liver samples from FNA|DRUG: Vaniprevir 300 mg|PROCEDURE: Liver samples from CNB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Olanzapine Versus Clozapine in Treatment Refractory Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: olanzapine vs. clozapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2216684 in Healthy Females
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: LY2216684|DRUG: Ortho Cyclen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Use of Sugammadex at the End of Case in Routine Anesthesia (MK-8616-023)
Status: COMPLETED
Conditions: Anesthesia, General
Interventions: DRUG: Sugammadex|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CLINICAL OUTCOME OF ENDOTRACHEAL INTUBATION IN NON-TRAUMA PATIENTS
Status: COMPLETED
Conditions: To Evaluate the Clinical Outcome (Complications) of Emergency Endotracheal Intubation in Non-traumatic Patients
Interventions: DEVICE: Macintosh Laryngoscope Vs Video Laryngoscope
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: RCT Comparing 21 and 22 G Needle in the Diagnosis of Sarcoidosis by EBUS TBNA
Status: COMPLETED
Conditions: Sarcoidosis
Interventions: OTHER: 21 G needle group|OTHER: 22 G needle group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Polysaccharide Antibody Response Study
Status: COMPLETED
Conditions: Specific Polysaccharide Antibody Deficiency
Interventions: BIOLOGICAL: Pneumovax 23 (Sanofi Pasteur MSD)|BIOLOGICAL: Typhim Vi (Sanofi Pasteur MSD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Gallium Ga 68-DOTATATE PET/CT in Predicting Tumor Growth in Patients With Meningiomas
Status: COMPLETED
Conditions: Meningioma
Interventions: PROCEDURE: Computed Tomography|RADIATION: Gallium Ga 68-DOTATATE|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial to Explore Symptomatic Therapy for Application Site Reaction to SPM962 in Healthy Subject
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Topical steroid (Dexamethasone)|DRUG: Topical antihistamine (Diphenhydramine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pyrotinib as Neoadjuvant Agent for Non-objective Response HER2-positive Early Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Pyrotinib|DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Docetaxel|DRUG: Epirubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CHECK Trial: A Comparison of Headache Treatment in the ED: Compazine Versus Ketamine
Status: COMPLETED
Conditions: Headache
Interventions: DRUG: Prochlorperazine|DRUG: Ketamine|DRUG: Diphenhydramine|DRUG: Ondansetron|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Thermal Pulsation Versus Warm Compress Treatment for Meibomian Gland Dysfunction
Status: COMPLETED
Conditions: Meibomian Gland Dysfunction
Interventions: DEVICE: thermal pulsation|OTHER: warm compress
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quarterback 2b - Sequential Therapy With Reduced Dose Chemoradiotherapy for HPV Oropharynx Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced HPV Positive Oropharynx Cancer
Interventions: RADIATION: PTV56|RADIATION: PTV50.4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Olanzapine to the Prophylaxis of Nausea and Vomiting Induced by Chemotherapy in Children and Adolescents
Status: UNKNOWN
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Ondansetron|DRUG: Dexamethasone|DRUG: Aprepitant|DRUG: Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Overfeeding Different Macronutrients on Whole-body Insulin Sensitivity
Status: UNKNOWN
Conditions: Insulin Resistance|Type 2 Diabetes|Glucose Metabolism Disorders|Metabolic Disease
Interventions: OTHER: High-fat diet|OTHER: High-carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the NSAIDS Sparing Effect of Etanercept in Subjects With Axial Spondyloarthritis
Status: COMPLETED
Conditions: Axial Spondyloarthritis
Interventions: DRUG: etanercept|DRUG: etanercept|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mucosal and Systemic Immunity After Viral Challenge of Healthy Volunteers Vaccinated With Inactivated Influenza Vaccine Via the Intranasal Versus Intramuscular Route
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Flucelvax(R)|OTHER: Human Challenge virus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: CARPALL: Immunotherapy With CD19/22 CAR T-cells for CD19+ Haematological Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Burkitt Lymphoma
Interventions: PROCEDURE: Leukapheresis|DRUG: Lymphodepletion with fludarabine|DRUG: Lymphodepletion with cyclophosphamide|BIOLOGICAL: CD19/22 CAR T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Periarticular Injection Versus Fascia Iliaca Block for Total Knee Arthroplasty
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: PROCEDURE: periarticular injection|PROCEDURE: fascia iliaca block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ylang Ylang Oil and Lemon Oil
Status: COMPLETED
Conditions: Pain, Labor|Anxiety|Aromatherapy
Interventions: OTHER: essential oils (Ylang ylang oil)|OTHER: placebo (saline solutions)|OTHER: essential oils (lemon oil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fall Detection and Prevention System for the Elderly
Status: UNKNOWN
Conditions: Accidental Falls
Interventions: DEVICE: Fall detection and prevention system|DEVICE: Sham fall detection and prevention system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Methods in Pain Caused by Orogastric Tube Placement in Preterm Newborns
Status: RECRUITING
Conditions: Pain
Interventions: OTHER: BREAST MILK|OTHER: KNITTED OCTOPUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Use of Biorepair Peribioma Toothpaste and Mousse for Home Oral Care in Patients Undergoing Periodontal Therapy
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: OTHER: Domiciliary oral care with Biorepair Peribioma Toothpaste + Mousse|OTHER: Domiciliary oral care with Curasept Toothpaste (chlorhexidine 0,2%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does a Preoperative Prophylactic Antibiotic Reduce Surgical Site Infection Following Wire-localized Lumpectomy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Cefazolin Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Explore Safety, Pharmacokinetics, and Early Clinical Signal of Efficacy of DS-2325a in Patients With Netherton Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Netherton Syndrome
Interventions: DRUG: DS-2325a|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Open Radical Cystectomy With Robot-assisted Cystectomy in Patients With Bladder Cancer
Status: COMPLETED
Conditions: Urinary Bladder Neoplasms
Interventions: PROCEDURE: Radical Cystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: PROACTIVE: Preventing Acute/Chronic GVHD With TocIlizumab Combined With GVHD Prophylaxis Post allogEneic Transplant
Status: COMPLETED
Conditions: Hematologic Malignancy
Interventions: DRUG: Tacrolimus|DRUG: Methotrexate|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metronomic Therapy for Pediatric Patients With Solid Tumors at High Risk of Recurrence
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: Bevacizumab|DRUG: Cyclophosphamide|DRUG: Valproic Acid|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Panobinostat in Combination With Bortezomib and Dexamethasone in Japanese Patients With Relapsed/Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Relapse/Refractory Multiple Myeloma
Interventions: DRUG: LBH589 (panobinostat)|DRUG: bortezomib|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cadonilimab/Anlotinib in Locally Advanced or Relapsed/Metastatic ESCC Patients After Failure of PD-1 Combined With Platinum-containing Chemotherapy
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Cadonilimab combined Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Peripheral Nerve Block and DepoDur in Total Knee Joint Replacement
Status: TERMINATED
Conditions: Arthroplasty, Replacement, Knee
Interventions: DRUG: Depodur|PROCEDURE: sciatic nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Mental Health Outcomes: Building an Adaptive Implementation Strategy
Status: TERMINATED
Conditions: Bipolar Disorder|Depression|Mood Disorder
Interventions: BEHAVIORAL: External Facilitation|BEHAVIORAL: External + Internal Facilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Feasibility of Neostigmine for Intraoperative Neuromonitoring in Thyroid Surgery
Status: COMPLETED
Conditions: Thyroid Diseases|Surgical Injury|Nerve Monitoring
Interventions: DRUG: Neostigmine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Safety and Efficacy of AGN-214868 in Patients With Postherpetic Neuralgia
Status: COMPLETED
Conditions: Neuralgia, Postherpetic
Interventions: DRUG: AGN-214868|DRUG: Placebo to AGN-214868
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dapagliflozin on the Progression From Prediabetes to T2DM in Subjects With Myocardial Infarction
Status: UNKNOWN
Conditions: PreDiabetes|Myocardial Infarction|T2DM (Type 2 Diabetes Mellitus)|CVD
Interventions: DRUG: Dapagliflozin 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addressing Post Cessation Weight Gain
Status: TERMINATED
Conditions: Obesity|Smoking Cessation
Interventions: DRUG: lorcaserin|DRUG: Varenicline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of OncoGel™ Added to Chemotherapy and Radiation Before Surgery in Subjects With Esophageal Cancer
Status: TERMINATED
Conditions: Esophageal Cancer|Adenocarcinoma of the Esophagus|Squamous Cell Carcinoma
Interventions: DRUG: OncoGel (Paclitaxel gel)|DRUG: cisplatin|DRUG: 5-FU|RADIATION: radiation therapy|PROCEDURE: esophageal resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Study of ALX-0171 in Infants Hospitalized for Respiratory Syncytial Virus Lower Respiratory Tract Infection
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Lower Respiratory Tract Infection
Interventions: BIOLOGICAL: ALX-0171 3.0 mg/kg|BIOLOGICAL: ALX-0171 6.0 mg/kg|BIOLOGICAL: ALX-0171 9.0 mg/kg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IUI vs. IVF/ICSI in Women Aged 38-42 Years: a Prospective Randomized Controlled Trial.
Status: UNKNOWN
Conditions: Infertility
Interventions: OTHER: Drug: Follitropine Bèta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of PREVENA in Reducing Surgical Site Complications Following Reversal of Ileostomy or Colostomy
Status: UNKNOWN
Conditions: Stoma Site Infection|Ileostomy - Stoma|Colostomy Stoma
Interventions: DEVICE: PREVENA Incision Management System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Efficacy and PK of BIVV001 in Pediatric Patients With Hemophilia A
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: efanesoctocog alfa (BIVV001)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arginine Treatment of Acute Chest Syndrome (Pneumonia) in Sickle Cell Disease Patients
Status: COMPLETED
Conditions: Anemia, Sickle Cell|Pneumonia
Interventions: DRUG: Arginine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Manual-Based Vocational Rehabilitation Program for Patients With Acquired Brain Injury
Status: UNKNOWN
Conditions: Brain Injuries
Interventions: BEHAVIORAL: Program -based vocational rehabilitation intervention|BEHAVIORAL: Conventional vocational rehabilitation (controls)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prevalence of SARS -Cov2 Carriage in Asymptomatic and Mildly-symptomatic Children
Status: COMPLETED
Conditions: Covid19
Interventions: DIAGNOSTIC_TEST: Data collection and rhinopharyngeal swab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC