pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Exercise and Therapeutic Learning Among Women With PTSD
Status: COMPLETED
Conditions: PTSD
Interventions: OTHER: Day 1 Assessments|OTHER: Day 2 Fear Learning|OTHER: Day 3 Fear Extinction|BEHAVIORAL: Moderate Intensity Exercise|BEHAVIORAL: Low Intensity Exercise|OTHER: Day 4 Recall of Fear Extinction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Recombinant Anti-IL-17A Humanized Monoclonal Antibody in Chinese Participants With Moderate-to-Severe Plaque Psoriasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Psoriasis
Interventions: DRUG: Recombinant Anti-IL-17A Humanized Monoclonal Antibody Injection|OTHER: Placebo|DRUG: Recombinant Anti-IL-17A Humanized Monoclonal Antibody Injection|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Single Stage Breast Reconstruction in Female Participants With Mastectomy
Status: TERMINATED
Conditions: Mastectomy and Breast Reconstruction
Interventions: PROCEDURE: Breast Reconstruction, Direct to Implant (DTI) with Strattice™|PROCEDURE: Two Stage Breast Reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Left-sided Cardiac Sparing Through the Use of 3-dimensional Surface Matching-based Deep Inspiration Breath Hold and Active Breathing Control
Status: COMPLETED
Conditions: Left-Sided Breast Cancer
Interventions: DEVICE: AlignRT system (VisionRT Ltd., London, UK)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Evaluation of Intracoronary Infusion of Allogeneic Human Cardiac Stem Cells in Patients With AMI
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: BIOLOGICAL: Allogeneic human cardiac stem cells (CSCs)|OTHER: Human Serum Albumin-HSA 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Game-Based Virtual Reality Application on the Development of Postoperative Care Skills of Nursing Students for Hysterectomy
Status: COMPLETED
Conditions: Nursing|Hysterectomy|Game-Based Learning
Interventions: OTHER: game based learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effect of VSL#3 (Original De Simone Formulation) on Cognitive Function, Risk of Falls and Quality of Life in Patients With Cirrhosis
Status: COMPLETED
Conditions: Cirrhosis|Cognitive Dysfunction
Interventions: DIETARY_SUPPLEMENT: VSL#3 (Original De Simone formulation)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 6-year Clinical Evaluation of Glass Ionomer Cements (GIS) With Resin Coating on Posterior Teeth
Status: COMPLETED
Conditions: Dental Caries
Interventions: OTHER: EquiaFil G-coat|OTHER: EquiaFil Fuji Varnish|OTHER: Riva SC G-coat|OTHER: Riva SC Fuji Varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Repeated Super-Selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Newly Diagnosed GBM
Status: COMPLETED
Conditions: Glioblastoma Multiforme|Brain Tumor
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Piloting ProHealth: A Program for Male Soldiers on Sex, Dating and Alcohol-Use at Fort Bragg
Status: UNKNOWN
Conditions: Sexual Assault and Rape|Risk Behavior|Alcohol Abuse
Interventions: OTHER: Surveys|OTHER: Interviews|OTHER: Group Discussions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: MECHANISMS OF NEURONAL RESILIENCE IN ALZHEIMER'S DISEASE AND ITS FOCAL VARIANTS: A PET/MR STUDY
Status: RECRUITING
Conditions: Alzheimer Disease, Early Onset|Posterior Cortical Atrophy
Interventions: DEVICE: TEP/IRM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Zoledronate With Atorvastatin in Renal Cell Carcinoma
Status: COMPLETED
Conditions: Kidney Cancer|Renal Cell Carcinoma
Interventions: DRUG: Zoledronate|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Energy Resonance by Skin Stimulation in the Management of Anxious Patients Who Require Scheduled Orthopaedic Surgery
Status: COMPLETED
Conditions: Patient Requiring Scheduled Conventional Orthopedic Surgical Intervention of the Upper or Lower Limb
Interventions: OTHER: Energy Resonance through Cutaneous Stimulation|OTHER: questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of LX1031 in Subjects With Non-Constipating Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: LX1031 High Dose|DRUG: LX1031 Low Dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plaque Regression and Progenitor Cell Mobilization With Intensive Lipid Elimination Regimen (PREMIER), Phase II
Status: COMPLETED
Conditions: Acute Coronary Artery Syndrome
Interventions: DEVICE: intensive LDL-lowering therapy|DRUG: standard statin monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: BIOlogical Response to Exercise : A Metabolomic Study in Peripheral Artery Disease (BIOR)
Status: COMPLETED
Conditions: Peripheral Artery Disease
Interventions: BIOLOGICAL: Capillary blood sampling from the earlobe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Brief Study To Evaluate The Safety, Tolerability, And Blood Levels Of Multiple Doses Of PF-044467943 Or Placebo In Combination With Donepezil In Subjects With Mild To Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: PF-04447943|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oncologic Impact of Splenectomy-omitting Radical Pancreatectomy in Well-selected Left-sided Pancreatic Cancer
Status: TERMINATED
Conditions: Left-sided Pancreatic Cancer|Ductal Adenocarcinoma
Interventions: PROCEDURE: Radical Antegrade Modular Pancreatectomy with Splenectomy|PROCEDURE: Radical Antegrade Modular Pancreatectomy without splenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Mediterranean Diet and Time-Restricted Eating Dietary Interventions for Psoriasis Study
Status: RECRUITING
Conditions: Psoriasis Vulgaris
Interventions: OTHER: The Mediterranean style diet|OTHER: The UK diet|OTHER: Time-restricted eating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Stem Cell Mobilization by G-CSF Post Myocardial Infarction to Promote Myocyte Repair
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: DRUG: Granulocyte Colony Stimulating Factor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Pragmatic Randomized Trial of Icosapent Ethyl for High-Cardiovascular Risk Adults
Status: TERMINATED
Conditions: Covid19|Atherosclerosis|Cardiovascular Diseases|Upper Respiratory Tract Infections
Interventions: DRUG: Icosapent ethyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cross -Over Study to Prove Bioequivalence Between Two Oral Formulations of Levonorgestrel
Status: COMPLETED
Conditions: Contraception|Contraception, Postcoital
Interventions: DRUG: Levonorgestrel Emergency Pill (BAY86-5028/Opxion)|DRUG: Levonorgestrel (Postday)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Hybrid Coronary Revascularization Trial
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Hybrid Coronary Revascularization (isolated LIMA-LAD)|DEVICE: Hybrid Coronary Revascularization (PCI)|DEVICE: Percutaneous Coronary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Imaging Techniques in Barrett's Esophagus
Status: COMPLETED
Conditions: Barrett Esophagus|Gastroesophageal Reflux
Interventions: OTHER: NBI-AFI imaging|OTHER: Standard Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Subcutaneously CM310/Placebo in Patients With Chronic Rhinosinusitis With Nasal Polyposis (CROWNS-1)
Status: COMPLETED
Conditions: Chronic Rhinosinusitis (Diagnosis)|Nasal Polyps
Interventions: BIOLOGICAL: CM310|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-polar RF and PEMF for Treatment of Vulvovaginal Atrophy
Status: COMPLETED
Conditions: Genitourinary Syndrome of Menopause|Vulvovaginal Atrophy|Menopause
Interventions: DEVICE: Radiofrequency and pulsed electro-magnetic fields treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of A-101 Topical Solution in Subjects With Dermatosis Papulosa Nigra
Status: COMPLETED
Conditions: Dermatosis Papulosa Nigra
Interventions: DRUG: A-101 Topical Solution 40%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antifungal Activity of Loceryl Nail Lacquer in Combination With a Cosmetic Varnish
Status: COMPLETED
Conditions: Foot Dermatoses
Interventions: DRUG: Loceryl NL + Cosmetic varnish|DRUG: Loceryl NL 12 weeks|DRUG: Loceryl NL 15 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Effects of SAM-531 on Sleep Electroencephalogram (EEG) and Quantitative Wake EEG in Healthy Subjects
Status: COMPLETED
Conditions: Healthy|Adult
Interventions: DRUG: SAM-531|OTHER: placebo|DRUG: Donepezil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Outcome Measures and Biomarkers in a Cohort of Spinal Muscular Atrophy Type III/ IV Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Muscular Atrophy
Interventions: OTHER: Blood Samples|OTHER: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PEG Solution (Laxabon®) 4L Versus Senna Glycoside (Pursennid® Ex-Lax) 36mg and PEG Solution (Laxabon®) 2L for Large Bowel Cleansing Prior to Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: PEG (solution given 4 L)|DRUG: senna glycoside 36 mg and PEG (solution given 2 L)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Expanded Access of Omidubicel, for Allogeneic Transplantation in Patients With Hematological Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematological Malignancies
Interventions: BIOLOGICAL: omidubicel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electroacupuncture Analgesia for Colonoscopy
Status: UNKNOWN
Conditions: Colonoscopy|Acupuncture
Interventions: DEVICE: Electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Beta-glucans for Hospitalised Patients With COVID-19
Status: NOT_YET_RECRUITING
Conditions: COVID-19
Interventions: DRUG: MC 3x3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine and Irinotecan in Treating Patients With Locally Advanced, Recurrent, or Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Capecitabine|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endovascular Repair for the Descending Thoracic Aorta
Status: COMPLETED
Conditions: Aorta Thoracic; Traumatic Rupture
Interventions: DEVICE: Valiant™ endoluminal procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validity and Reliability of the Turkish Version of the Ottawa Sitting Scale in Hemodialysis Patients With Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Diseases
Interventions: OTHER: hemodialysis group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Testing and Linkage to Care for Injecting Drug Users in Kenya
Status: COMPLETED
Conditions: HIV Infection|HCV Coinfection
Interventions: BEHAVIORAL: POC CD4 and Peer Case Management|DRUG: HCV+PWID|BEHAVIORAL: Control - No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Body Composition and Serum Biochemistry After Intravenous Infusion or Oral Intake of Saline in Healthy Volunteers
Status: COMPLETED
Conditions: Edema|Perioperative/Postoperative Complications
Interventions: OTHER: Oral saline|OTHER: Intravenous saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Hemostatic Effect of Intrauterine Instillation of Oxytocin in Hysteroscopic Myomectomy
Status: COMPLETED
Conditions: Leiomyoma
Interventions: DRUG: Oxytocin|OTHER: sterile bacteriostatic water ampule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Video-guided Percutaneous Tracheostomy (PCT): A Feasibility Study
Status: UNKNOWN
Conditions: Bleeding|Hypoxia|Atelectasis|Pneumothorax|Pneumomediastinum
Interventions: DEVICE: video-guided PCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cyrolipolysis vs Cyrolipolysis and Subcision for Cellulite
Status: ACTIVE_NOT_RECRUITING
Conditions: Cellulite
Interventions: PROCEDURE: cyrolipolysis (CoolSculpting device)|PROCEDURE: subcision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicentre, Double-Blind, Double-Dummy, Randomised Study of the Analgesic Efficacy and Safety of Valdecoxib Compared to Diclofenac Sodium in Patients Undergoing Knee Arthroscopy for Anterior Cruciate Ligament (ACL) Reconstruction
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: valdecoxib|DRUG: diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First-Line Treatment of Advanced Non-Small-Cell Lung Cancer With Negative Driver Gene: a Multicenter, Single-Arm Trial
Status: RECRUITING
Conditions: Non-Small-Cell Lung Cancer
Interventions: DRUG: Recombinant human endostatin (Endostar)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Evogliptin When Added to Ongoing Metformin and Dapagliflozin Combination Therapy in Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: DRUG: Evogliptin 5mg|DRUG: Evogliptin Placebo|DRUG: Dapagliflozin 10mg|DRUG: Metformin ≥ 1000mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Flow Restriction Therapy Combined With Neuromuscular Electrostimulation in Amateur Female Soccer Players
Status: COMPLETED
Conditions: Knee
Interventions: OTHER: Electrostimulation|OTHER: Blood flow restriction therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Usage of Squeezable vs Standard Bottles After Cleft Palate Surgery on the Feeding Process of Infants
Status: COMPLETED
Conditions: Bottle Feeding
Interventions: PROCEDURE: Standart bottle|PROCEDURE: Squeezable bottle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Capsular Tension Rings in Intraocular Lens Rotation
Status: TERMINATED
Conditions: Cataract|Ophthalmoplegia|Ophthalmologic Complication
Interventions: DEVICE: MORCHER® EYEJET® CTR Types 14, 14A, and 14C|DEVICE: Toric IOL Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MCT and Capsaicin Provocation Challenge in Diagnosis of Chronic Cough
Status: COMPLETED
Conditions: Cough|Cough Variant Asthma|Upper-Airway Cough Syndrome|GERD|Allergic Rhinitis
Interventions: OTHER: Cough variant asthma treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preventing Respiratory Viral Illness Invisibly
Status: ENROLLING_BY_INVITATION
Conditions: COVID-19 Respiratory Infection|Respiratory Virus Infection|Influenza -Like Illness
Interventions: OTHER: Far-UVC light as an additional method of disinfection|OTHER: Placebo fluorescent light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Management of Distally Extension Maxillary Atrophied Ridge With Two Different Minimal Invasive Treatment Modalities
Status: ACTIVE_NOT_RECRUITING
Conditions: Partial Edentulism Class 2 Due to Periodontal Disease
Interventions: PROCEDURE: Closed sinus lift procedure|DEVICE: Crestal sinus lift
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Neuromuscular Electrical Multisite System on Cardiovascular Effects in Severe Obese Patients
Status: UNKNOWN
Conditions: Obesity|Arterial Stiffness|Electrical Stimulation|Training|Cardiovascular
Interventions: DEVICE: Multisite NMES training during 6 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Serratus Anterior Plan Block (SAP) and Pectoralis (PECSI-II) Blocks on Left Internal Mammarian Artery (LIMA) Blood Flow
Status: RECRUITING
Conditions: Chest Wall Blocks
Interventions: PROCEDURE: LIMA Blood flow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Effect of Doxium on High Sensitivity CRP and Endothelin-1 Serum Levels in Patients With Diabetic Retinopathy
Status: UNKNOWN
Conditions: Diabetic Retinopathy
Interventions: DRUG: Calcium dobesilate (Doxium)|DRUG: Placebo drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Single and Multiple Doses of TLC-2716 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: TLC-2716|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Intraosseous Periodontal Defects With Hyaluronic Acid
Status: COMPLETED
Conditions: Periodontal Bone Loss|Periodontal Pocket
Interventions: OTHER: MINSD and Hyaluronic acid|OTHER: MINSD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Preliminary Effects of Fasting-Mimicking Diet in Asian Americans With Prediabetes
Status: RECRUITING
Conditions: Prediabetes|Prediabetic State
Interventions: BEHAVIORAL: Fasting Mimicking Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Arotinolol Hydrochloride on Morning Blood Pressure and Heart Rate
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Arotinolol Hydrochloride|DRUG: Metoprolol succinate sustained-release tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Intraoperative ESKAPE Transmission Through Use of a Personal Hand Hygiene System
Status: RECRUITING
Conditions: Surgical Wound Infection|Cross Infection
Interventions: DEVICE: SafeHaven Automated Hand Hygiene Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Trial of Supplemental Vitamin A and Nicotinamide
Status: NOT_YET_RECRUITING
Conditions: Skin Cancer|Kidney Transplant Recipients
Interventions: DRUG: Vitamin A|DRUG: Nicotinamide|OTHER: Other: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Shift Work on Nurse Staff Health
Status: COMPLETED
Conditions: Shift Work Type Circadian Rhythm Sleep Disorder|Chronobiology Disorders|Mood Swing|Physical Activity|Cardiovascular Diseases
Interventions: OTHER: Shifts working hours with different schedules
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Safety and Tolerability Profile of TR399 in Healthy Volunteers and Erectile Dysfunction Patients
Status: UNKNOWN
Conditions: Erectile Dysfunction
Interventions: DRUG: TR-399 (5% Vardenafil HCl·3H2O, topical gel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oculomotor and Vestibular Ocular Reflex Exercises in Patients With Benign Paroxysmal Positional Vertigo
Status: COMPLETED
Conditions: Benign Paroxysmal Positional Vertigo (Disorder)
Interventions: OTHER: Traditional physical therapy using Epley's maneuver|OTHER: Oculomotor and Vestibular Ocular Reflex (VOR) exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Glucose Response After Oral Intake of Lactulose in Healthy Volunteers
Status: COMPLETED
Conditions: Blood Glucose
Interventions: DIETARY_SUPPLEMENT: Lactulose crystals 10 g|DIETARY_SUPPLEMENT: Lactulose crystals 20 g|DIETARY_SUPPLEMENT: Lactulose liquid 10 g|DIETARY_SUPPLEMENT: Lactulose liquid 20 g|DIETARY_SUPPLEMENT: Oral glucose 20 g|DIETARY_SUPPLEMENT: Still water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treating Young Patients With Newly Diagnosed, Low Stage, Lymphocyte Predominant Hodgkin Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Ann Arbor Stage I Childhood Hodgkin Lymphoma|Ann Arbor Stage II Childhood Hodgkin Lymphoma|Childhood Nodular Lymphocyte Predominant B-Cell Lymphoma
Interventions: PROCEDURE: Conventional Surgery|DRUG: Cyclophosphamide|DRUG: Doxorubicin Hydrochloride|DRUG: Prednisone|RADIATION: Radiation Therapy|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Sound and Speech Perception in New Cochlear Implanted Subjects Using or Not an Anatomy-based Fitting
Status: RECRUITING
Conditions: Sensorineural Hearing Loss, Bilateral
Interventions: DEVICE: anatomy-based fitting then default fitting|DEVICE: default fitting then anatomy-based fitting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Comparative Trial to Investigate the Efficacy and Safety of Desmopressin for the Treatment of Nocturia in Adult Men
Status: COMPLETED
Conditions: Nocturia
Interventions: DRUG: A: Desmopressin 25 µg|DRUG: B. Desmopressin 50 µg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Prehabilitation in Frail and Non-frail Patients Waiting for a Kidney Transplantation (the FRAILMAR Study)
Status: RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: OTHER: Multimodal prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine if a New Nicotine Replacement Therapy Can Safely Help Smokers to Quit Smoking
Status: TERMINATED
Conditions: Tobacco Dependence
Interventions: DRUG: Placebo|DRUG: Nicotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effect Of Luteolin Natural Extract Versus Its Nanoparticles On Tongue Squamous Cell Carcinoma Cell Line
Status: UNKNOWN
Conditions: Tongue Neoplasms|Carcinoma
Interventions: DRUG: luteolin|DRUG: nano-luteolin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intersectoral Platform (SÜP) of the National Pandemic Cohort Network (NAPKON)
Status: UNKNOWN
Conditions: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
Interventions: OTHER: Observational of different courses of SARS-CoV-2 infection in different phases (acute vs. post-acute) and settings
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Myocardial Ischemia Without Obstructive Coronary Stenoses
Status: RECRUITING
Conditions: Myocardial Ischemia|Non-Obstructive Coronary Atherosclerosis|Microvascular Coronary Artery Disease|Vasospastic Angina|Myocardial Bridging
Interventions: DIAGNOSTIC_TEST: Invasive coronary endothelium-dependent and non-endothelium-dependent physiological assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Dose Finding and Safety Study of CC-220, Alone and in Combination With an Anti-CD20 Monoclonal Antibody (mAb) in Subjects With Relapsed or Refractory Lymphomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma
Interventions: DRUG: CC-220|DRUG: Rituximab|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In Vitro Follicle Activation
Status: TERMINATED
Conditions: Primary Ovarian Insufficiency|Infertility
Interventions: PROCEDURE: In Vitro Follicle Activation (IVA)|DRUG: Follicle Activation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia
Status: COMPLETED
Conditions: Homozygous Familial Hypercholesterolemia (HoFH)
Interventions: DRUG: Rosuvastatin 20mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Extension Study of RAD011 (Cannabidiol Oral Solution) in Patients With Prader-Willi Syndrome
Status: WITHDRAWN
Conditions: Prader-Willi Syndrome
Interventions: DRUG: RAD011
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Multimodal Treatment Approach for Children With Spastic Diplegic Cerebral Palsy
Status: UNKNOWN
Conditions: Spastic Diplegic Cerebral Palsy
Interventions: OTHER: Selected physical therapy program|PROCEDURE: Interrupted serial casting|DEVICE: Neuromuscular electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Octaplex (Human Prothrombin Complex Concentrate) and Fresh Frozen Plasma in Patients Under Vitamin K Therapy Antagonist Needing Urgent Surgery or Invasive Procedures
Status: COMPLETED
Conditions: Reversal of Anticoagulant Treatment
Interventions: BIOLOGICAL: Octaplex (human prothrombin complex concentrate)|BIOLOGICAL: Fresh frozen plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effect of Direct Current Stimulation on Cognitive Function of Mild to Moderate Alzheimer Patients
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: PROCEDURE: Direct current stimulation using Anodal electrode|PROCEDURE: direct current stimulation using cathodal electrode|PROCEDURE: Sham direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan and Carboplatin as First-Line Therapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Carboplatin|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Intervention to Improve Function in Severe Cardiopulmonary Illness
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)|Heart Failure
Interventions: BEHAVIORAL: Exercise adherence|BEHAVIORAL: Self-management- prevention of illness|BEHAVIORAL: Self-management of illness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Analysis of the Performance of 1060 nm Diode and Radio Frequency Prior to Abdominoplasty
Status: COMPLETED
Conditions: Adipose Tissue Atrophy
Interventions: DEVICE: Venus Bliss
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Aspirin Versus Aspirin + ClopidogRel Following Transcatheter Aortic Valve Implantation: the ARTE Trial
Status: COMPLETED
Conditions: Aortic Valve Disease|Myocardial Infarction|Stroke
Interventions: DRUG: Aspirin (80 mg/d) + clopidogrel (75 mg/d)|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Akt Inhibitor MK2206 in Patients With Relapsed Lymphoma
Status: COMPLETED
Conditions: Adult Nasal Type Extranodal NK/T-cell Lymphoma|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|B-cell Adult Acute Lymphoblastic Leukemia|B-cell Chronic Lymphocytic Leukemia|Cutaneous B-cell Non-Hodgkin Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Hepatosplenic T-cell Lymphoma|Intraocular Lymphoma|Nodal Marginal Zone B-cell Lymphoma|Noncutaneous Extranodal Lymphoma|Peripheral T-cell Lymphoma|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Refractory Hairy Cell Leukemia|Small Intestine Lymphoma|Splenic Marginal Zone Lymphoma|T-cell Adult Acute Lymphoblastic Leukemia|T-cell Large Granular Lymphocyte Leukemia|Testicular Lymphoma|Waldenström Macroglobulinemia
Interventions: DRUG: Akt inhibitor MK2206|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Rate (Slope) of Compression on the Incidence of Symptomatic ETD and MEB: a Phase III Prospective Study.
Status: RECRUITING
Conditions: Ear Barotrauma|Middle Ear Disease|Ear Diseases|Pressure Injury|Eustachian Tube Dysfunction|Middle Ear; Injury|Middle Ear Barotrauma
Interventions: PROCEDURE: Compression Profile/Schedule: 15 minute Non-Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw)|PROCEDURE: Compression Profile/Schedule: 15 minute Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Long Acting FSH Plus Antagonist Versus Daily FSH Plus Antagonist Versus Short Agonist Protocol in Poor Responders Undergoing IVF
Status: UNKNOWN
Conditions: Female Infertility|Poor Responder
Interventions: DRUG: Long acting FSH and GnRH antagonist|DRUG: Daily FSH and GnRH antagonist|DRUG: Triptorelin and recombinant FSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Whole Body Vibration in Elderly Patients Requiring Rehabilitation: A Pilot Study
Status: WITHDRAWN
Conditions: Neuromuscular Deficits|Musculoskeletal Deficits
Interventions: DEVICE: whole body vibration using a Galileo vibrating platform
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Nabiximols Oromucosal Spray as Add-on Therapy in Participants With Spasticity Due to Multiple Sclerosis
Status: TERMINATED
Conditions: Multiple Sclerosis (MS)
Interventions: DRUG: Nabiximols|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Choline Alphoscerate-Nimodipine in Vascular Cognitive Impairment
Status: COMPLETED
Conditions: Vascular Cognitive Impairment
Interventions: DRUG: Choline alphoscerate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Are Cognition and Sleep Affected by Exposure to Carbon Dioxide and Bio Effluents During Sleep?
Status: COMPLETED
Conditions: Cognitive Impairment, Mild|Sleep|Environmental Exposure
Interventions: OTHER: Good ventilation|OTHER: Ventilation CO2|OTHER: Poor Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ST266 Eyedrops for the Treatment of Persistent Corneal Epithelial Defects
Status: TERMINATED
Conditions: Persistent Corneal Epithelial Defect
Interventions: BIOLOGICAL: ST266|OTHER: 0.67% Sodium Chloride Ophthalmic Solution|BIOLOGICAL: Open-label ST266
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Doses of PF-04958242 in Subjects With Stable Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: PF-04958242|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Seasonal Influenza DNA Vaccine & Seasonal Influenza Trivalent Inactivated Vaccine (TIV) in Children & Adolescents
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Seasonal Influenza DNA vaccine|BIOLOGICAL: TIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Partial Pulpotomy in Mature Permanent Teeth With Signs and Symptoms of Irreversible Pulpits
Status: COMPLETED
Conditions: Irreversible Pulpitis
Interventions: PROCEDURE: Vital Pulp therapy-Partial pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Market Celect Platinum Vena Cava Filter and Gunther Tulip Retrieval Set Study
Status: NOT_YET_RECRUITING
Conditions: Deep Vein Thrombosis|Venous Thromboembolism|Pulmonary Embolism
Interventions: DEVICE: Celect Platinum Vena Cava Filter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Safety and Efficacy of a rhPTH[1-84] of Fixed Doses of 25 and 50 mcg in Adults With Hypoparathyroidism (RELAY)
Status: COMPLETED
Conditions: Hypoparathyroidism
Interventions: DRUG: NPSP558
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conservative Versus Non-conservative Treatment for Severe Dental Caries
Status: COMPLETED
Conditions: Dental Caries
Interventions: OTHER: Conservative treatment: pulpectomy and composite resin crown|OTHER: Non-conservative treatment: Tooth extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of HIV on Glutathione Synthesis and Oxidative Stress
Status: COMPLETED
Conditions: HIV Infection|Erythrocyte Glutathione Deficiency
Interventions: DIETARY_SUPPLEMENT: Cysteine (as n-acetylcysteine) and glycine|DIETARY_SUPPLEMENT: Cysteine/glycine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Belantamab Mafodotin in Combination With Nirogacestat and Pomalidomide in People With Multiple Myeloma That Has Not Responded to Treatment or Has Come Back After Treatment
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Belantamab Mafodotin|DRUG: Nirogacestat|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies
Status: RECRUITING
Conditions: Recurrent Ependymoma|Recurrent Medulloblastoma|CNS Malignancies
Interventions: DRUG: Nivolumab|DRUG: Methotrexate|DRUG: 5-Azacytidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double-Blind Randomized Placebo-Controlled Trial on Clinical and Biological Effects of Oral Corticosteroids or Doxycyclin in Patients With Nasal Polyposis
Status: COMPLETED
Conditions: Nasal Polyposis
Interventions: DRUG: Administration of oral methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: China Pilot of ICOPE (Integrated Care for Older People) in Chaoyang
Status: COMPLETED
Conditions: Aging|Healthy Aging|Utilization, Health Care
Interventions: OTHER: ICOPE|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Manifestation of Surface EMG of Swallowing Muscles in Stroke Patients With Respiratory Muscle Training
Status: COMPLETED
Conditions: Cerebrovascular Disorders
Interventions: OTHER: Respiratory muscle training for IMST|OTHER: Regular Rehabilitation|OTHER: Respiratory muscle training for EMST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of Low-intensity Gamma rTMS on Cognitive and EEG Parameters in Adults With Mild Dementia by Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease|Mild Dementia
Interventions: DEVICE: low-intensity rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of BO-112 in Adult Patients With Aggressive Solid Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Part 1: BO-112|DRUG: Part 2: BO-112
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Hepatic Transarterial Administrations of NKR-2 in Patients With Unresectable Liver Metastases From Colorectal Cancer
Status: TERMINATED
Conditions: Colon Cancer Liver Metastasis
Interventions: BIOLOGICAL: NKR-2 cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pelvic Floor Muscle Training in Gymnasts With Stress Urinary Incontinence
Status: TERMINATED
Conditions: Urinary Incontinence|Stress Urinary Incontinence
Interventions: OTHER: Pelvic Floor Muscle Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Follow-up Study of Male Adults With Hemophilia B Previously Treated With Etranacogene Dezaparvovec (CSL222)
Status: ENROLLING_BY_INVITATION
Conditions: Hemophilia B
Interventions: GENETIC: AAV5-hFIXco-Padua
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pelvic Floor Consciousness in Women With Pelvic Floor Dysfunction
Status: COMPLETED
Conditions: Pelvic Floor Disorders
Interventions: OTHER: Active exercises of the pelvic floor muscles & Electrostimulation & Biofeedback|OTHER: Active exercises of the pelvic floor muscles & Biofeedback|OTHER: Active exercises of the pelvic floor muscles & Transabdominal US Biofeedback|OTHER: Active exercises of the pelvic floor muscles & Electrostimulation &Transabdominal US Biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BRITEPath- Phase 2
Status: COMPLETED
Conditions: Depression|Suicidal Ideation
Interventions: BEHAVIORAL: BRITEPath|BEHAVIORAL: Treatment As Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of an Artificial Pancreas in Patients Undergoing Hepatic Resection
Status: COMPLETED
Conditions: Liver Diseases
Interventions: DEVICE: the closed-loop STG-22 system (Nikkiso Inc, Tokyo, Japan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Oral Salmon Calcitonin in the Treatment of Osteoporosis in Postmenopausal Women Taking Calcium and Vitamin D
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: SMC021 Oral calcitonin|DRUG: SMC021 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Sequential Strategies to Reduce Readmission in a Diverse Population
Status: COMPLETED
Conditions: Hospital Readmission|Post-discharge Care Transitions|Congestive Heart Failure|Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Patient Navigator|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH