pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Hypoglycemia at Initiation of Pump Therapy in Children With Type 1 Diabetes
Status: UNKNOWN
Conditions: Type 1 Diabetes
Interventions: OTHER: Observation of hypoglycemias frequency 3 days before and after pump initiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effectiveness of Preoperative Surgical Scrubbing Using Clorhexidine Digluconate and Parachlorometaxylenol (ECP)
Status: COMPLETED
Conditions: Skin Diseases|Surgical Site Infection
Interventions: PROCEDURE: Preparatory handwash|PROCEDURE: Preoperative surgical scrubbing using 3% PCMX|PROCEDURE: Preoperative surgical scrubbing using 4% CHG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Transitioning Youth Out of Homelessness 2.5 (TYOH 2.5)
Status: NOT_YET_RECRUITING
Conditions: Homelessness|Youth
Interventions: BEHAVIORAL: Co-Designed Strengths-Based Leadership Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics and Pharmacodynamics Study With 2B3-201 in Healthy Subjects and Multiple Sclerosis(MS) Patients
Status: TERMINATED
Conditions: Healthy Volunteers|Multiple Sclerosis
Interventions: DRUG: 2B3-201|DRUG: Placebo|DRUG: Methylprednisolone hemisuccinate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Gemigliptin, Dapagliflozin, Empagliflozin DDI Study
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Gemigliptin|DRUG: Dapagliflozin|DRUG: Empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EMERGEncy Versus Delayed Coronary Angiogram in Survivors of Out-of-hospital Cardiac Arrest
Status: COMPLETED
Conditions: Out-of-Hospital Cardiac Arrest
Interventions: OTHER: Immediate coronary angiogram|OTHER: Delayed coronary angiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gonadal Tissue Freezing for Fertility Preservation in Individuals at Risk for Ovarian Dysfunction, Premature Ovarian Insufficiency and Clinically Indicated Gonadectomy
Status: RECRUITING
Conditions: Turner Syndrome|Post-menarcheal Adolescents|Ovarian Disfunction|Galactosemia|Variations in Sex Characteristics|Differences in Sex Development
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A One Year Open Label Study Assessing the Safety and Tolerability of Vilazodone in Patients With Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: vilazodone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABVN Phase 2-Studying the Effect of Stimulation on the Auricular Branch of the Vagal Nerve
Status: RECRUITING
Conditions: Gastroparesis
Interventions: OTHER: abvn|OTHER: PENFS- Percutaneous Electrical Nerve Field Stimulation|DEVICE: wrist worn Corsano Cardio Watch 287-2B)-|DEVICE: Gastroelectric Stimulator (GES)|DEVICE: TaVNS (Transcutaneous Auricular Vagal Nerve Stimulation) Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Affect of Health Education on Statins Medication Persistence and ClinicaL Prognosis of Ischemic Stroke Patients (HELP)
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: BEHAVIORAL: multiple health education interventions|BEHAVIORAL: conventional health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Trial of Standard Chemotherapy, With or Without BSI-201, in Patients With Triple Negative Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: gemcitabine/carboplatin|DRUG: iniparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of Clonidine Hydrochloride Topical Gel, 0.1% in the Treatment of Painful Diabetic Neuropathy
Status: COMPLETED
Conditions: Painful Diabetic Neuropathy|Diabetes
Interventions: DRUG: clonidine hydrochloride topical gel, 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbiota in Skin and Mucosa of Patients With Inflammatory Skin Diseases
Status: NOT_YET_RECRUITING
Conditions: Fungal Infection|Inflammatory Skin Disease|Yeast Infection Skin
Interventions: OTHER: sample collection (swap or tape strip)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immunogenicity After Revaccination With 23-valent Pneumococcal Polysaccharide Vaccine: Healthy Elderly People Versus Diabetic Patients
Status: UNKNOWN
Conditions: Pneumococcal Infections
Interventions: DRUG: ProDiax-23 (PPSV23)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the NeuroMuscular Junction Using the Single Fiber Electromyography and Reliability of Train-Of-Four in Critically Ill Patients.
Status: UNKNOWN
Conditions: Critical Illness Polyneuropathy|Critical Illness Myopathy|Weakness Due to Disease|Neuromuscular Blockade
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Feng Shui Delivery Room Design on Maternal and Infant Health
Status: UNKNOWN
Conditions: Delivery Problem|Delivery Fear|Delivery; Injury|Birth; Prolonged|Birth Disorder
Interventions: OTHER: Designing the birthing unit according to the philosophy of Feng Shui
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Randomized Study of Early Surgery Vs Multiple Sequential Antiepileptic Drug Therapy for Infantile Spasms Refractory to Standard Treatment
Status: COMPLETED
Conditions: Spasms, Infantile|Epilepsy
Interventions: DRUG: carbamazepine|DRUG: corticotropin|DRUG: nitrazepam|DRUG: pyridoxine|DRUG: valproic acid|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Educational Intervention to Increase Select Guideline-recommended Cardioprotective Medications in Patients With Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Cardiovascular Diseases
Interventions: OTHER: Educational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Yoga-mindfulness for Pain Management in Inflammatory Arthritis
Status: SUSPENDED
Conditions: Rheumatoid Arthritis|Psoriatic Arthritis|Pain
Interventions: BEHAVIORAL: Yoga-mindfulness|BEHAVIORAL: Patient education and physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of Doxazosin for Nightmares, Sleep Disturbance, and Non-Nightmare Clinical Symptoms in PTSD
Status: ACTIVE_NOT_RECRUITING
Conditions: Stress Disorders, Post-Traumatic
Interventions: DRUG: Doxazosin Mesylate, Extended Release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intracutaneous Versus Transcutaneous Sutures in the Face (IC vs TC Sutures)
Status: COMPLETED
Conditions: Skin Tumour|Surgery
Interventions: PROCEDURE: Transcutaneous sutures|PROCEDURE: Intracutaneous sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Convenience on Whole Grain Consumption
Status: NOT_YET_RECRUITING
Conditions: Health Behavior|Diet, Healthy|Diet Habit
Interventions: BEHAVIORAL: Ready to Eat (RTE)|BEHAVIORAL: Dried
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combination of Ibrutinib and Bortezomib to Treat Patients With Mantle Cell Lymphoma
Status: TERMINATED
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Ibrutinib|DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial of Universal Donor NK Cell Therapy in Combination With ALT803
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome|Acute Lymphoblastic Leukemia|Chronic Myeloid Leukemia|Chronic Lymphocytic Leukemia|Non Hodgkin Lymphoma|Hodgkin Lymphoma|Myeloproliferative Syndromes|Plasma Cell Myeloma|Colon Carcinoma|Adenocarcinoma of Rectum|Soft Tissue Sarcoma|Ewing's Sarcoma|Rhabdomyosarcoma
Interventions: BIOLOGICAL: Natural Killer (NK) Cells|BIOLOGICAL: ALT803
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab (MK-3475) or Placebo Given With Best Supportive Care in Asian Participants With Previously Treated Advanced Hepatocellular Carcinoma (MK-3475-394/KEYNOTE-394)
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Hepatocellular
Interventions: BIOLOGICAL: pembrolizumab|DRUG: placebo|OTHER: best supportive care (BSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial in Women With Coronary Artery Disease Investigating the Effects of Aerobic Interval Training Versus Moderate Intensity Continuous Exercise
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: OTHER: AIT Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Metabolic Effects of Egg Protein and Unsaturated Fat Intakes in Subjects With Hypertriglyceridemia
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: OTHER: Egg protein/unsaturated fatty acid|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sofosbuvir/Velpatasvir Fixed-Dose Combination (FDC) and Sofosbuvir/Velpatasvir FDC and Ribavirin in Participants With Chronic Genotype 3 HCV Infection and Cirrhosis
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: SOF/VEL|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Filgrastim in Treating Patients With Locally Recurrent or Advanced Urothelium Cancer
Status: UNKNOWN
Conditions: Bladder Cancer|Transitional Cell Cancer of the Renal Pelvis and Ureter
Interventions: BIOLOGICAL: filgrastim|DRUG: docetaxel|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Preoperative Irinotecan Drug-eluting Beads for Patients With Unresectable Colorectal Liver Metastasis
Status: UNKNOWN
Conditions: Colorectal Cancer|Liver Metastases
Interventions: DRUG: Trans arterial chemoembolization with Irinotecan Drug-eluting Beads
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of 2-Liter Mixed Preparation With Bisacodyl Plus Polyethylene Glycol and 4-Liter Polyethylene Glycol for Colon Cleansing in Patients With Prior History of Colorectal Resection
Status: COMPLETED
Conditions: Intestinal Cancer
Interventions: DRUG: Polyethylene glycol|DRUG: Bisacodyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Broad-spectrum Cognitive Remediation: Effects of a Brain Plasticity-based Program in Mild Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: OTHER: Computerized Plasticity-based Adaptive Cognitive Training|OTHER: Commercially available computerized training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Intravenous Tranexamic Acid With Anatomic and Reverse Total Shoulder Arthroplasty
Status: COMPLETED
Conditions: Blood Loss|Anatomic Total Shoulder Arthroplasty|Reverse Total Shoulder Arthroplasty|Transfusion|Tranexamic Acid
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation Enhanced by Partial Arterial Inflow Restrictions
Status: ACTIVE_NOT_RECRUITING
Conditions: Closed Femur Fracture
Interventions: OTHER: Blood Flow Restriction|DEVICE: Delfi PTSII Tourniquet System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase-IV, Open-label Study to Evaluate Safety/Tolerability of Once-daily AVAMYS (TM) Aqueous Nasal Spray 110mcg Among Vietnamese Adult Patients With Established Perennial Allergic Rhinitis
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: Avamys aqueous nasal spray 110mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Study of SI000413 in Knee Osteoarthritis Patients
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DRUG: SI000413|DRUG: microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: a Low-residue Diet for Bowel Preparation
Status: COMPLETED
Conditions: Colon Polyp|Colorectal Adenoma
Interventions: DIETARY_SUPPLEMENT: Prepackaged Low-residue diet|DIETARY_SUPPLEMENT: Self-prepared Low-residue diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Potential Role of Intravenous Lidocaine Versus Intravenous Ketamine for Pain Management in Fibromyalgia Patients
Status: RECRUITING
Conditions: Anesthesia
Interventions: DRUG: Lidocaine group|DRUG: Ketamine group|DRUG: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study of a Combination Antihypertensive Drug in the Treatment of Various Groups of Patients Who do Not Respond to Single Drug Treatment of Their High Blood Pressure
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: amlodipine and olmesartan medoxomil tablets|DRUG: hydrochlorothiazide tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nitrate Supplementation in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DIETARY_SUPPLEMENT: Nitrate supplementation|DIETARY_SUPPLEMENT: Placebo supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fludarabine, Velcade and Rituximab for Relapsed or Refractory Follicular Non-Hodgkin Lymphoma
Status: TERMINATED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: Fludarabine|DRUG: Velcade|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining Carryover Effect in Patients Treated witH Spinal cOrd Stimulation (ECHO)
Status: COMPLETED
Conditions: Neuralgia|Spinal Cord Stimulation
Interventions: DEVICE: Temporary device deactivation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Analgesic Requirements in Patients Receiving Nuss Operation Using 2 Different Anesthetic Adjuvants
Status: UNKNOWN
Conditions: Chest Wall Disorder
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Incremental Value of Magnetic Resonance Imaging in Selection of Pancreatic Cancer Patients for Surgery
Status: RECRUITING
Conditions: Pancreatic Cancer|Pancreatic Neoplasm|Liver Metastases
Interventions: DIAGNOSTIC_TEST: Preoperative MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dose-Finding Study Evaluating Effect on Body Composition of Enobosarm in Patients Taking a GLP-1 for Chronic Weight Mgmt
Status: ACTIVE_NOT_RECRUITING
Conditions: Muscle Loss|Obesity
Interventions: DRUG: Enobosarm|DRUG: Semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Cohort Study Depending on the Use of Palliative Care for Advanced Stage of Cancer Patients
Status: COMPLETED
Conditions: Stage IV Breast Cancer|Stage IV Pancreatic Cancer|Stage IV Colon Cancer|Stage IV Gastric Cancer|Stage IV Lung Cancer|Stage IV Liver Cancer|Malignant Hematologic Neoplasm|Biliary Cancer Metastatic|Pediatric Leukemia|Pediatric Lymphoma|Pediatric Brain Tumor|Pediatric Solid Tumor
Interventions: BEHAVIORAL: Early palliative care|BEHAVIORAL: Routine hospice care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Automatic Oxygen Control for Reducing Extremes of Oxygen Saturation (AreOS): A Randomised Control Trial
Status: COMPLETED
Conditions: Prematurity
Interventions: DEVICE: Automatic Oxygen control|OTHER: Manual Oxygen Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AUSTrian Randomized Interventional Study on Dialysis Accesses
Status: UNKNOWN
Conditions: End Stage Renal Disease|Catheter Infection|Shunt Malfunction
Interventions: DEVICE: Arteriovenous Fistula|DEVICE: Tunneled Cuffed Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Evaluation of Changes in Diaphragm Induced by Osteopathic Manipulative Techniques
Status: COMPLETED
Conditions: Diaphragm|Respiratory Muscles|Osteopathic Medicine|Ultrasonography
Interventions: OTHER: Osteopathic manipulative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Noninvasive Ventilation Strategies in Preterm Infants Following Extubation
Status: COMPLETED
Conditions: Intubated Infants Were Intend to Extubation Using Noninvasive Ventilation Strategies
Interventions: DEVICE: NHFOV|DEVICE: NCPAP|DEVICE: NIPPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-56021927 (ARN-509) and Abiraterone Acetate in Participants With Metastatic Castration-Resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms|Metastatic Castration-Resistant Prostate Cancer
Interventions: DRUG: Abiraterone Acetate|DRUG: Prednisone|DRUG: JNJ-56021927
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Remote Ischemic Preconditioning as Non Pharmacologic Strategy to Prevent Contrast Induced Nephropathy (PAIR)
Status: WITHDRAWN
Conditions: Contrast-induced Nephropathy
Interventions: PROCEDURE: Ischemic preconditioning|DRUG: Endovenous normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sorafenib Phase II Study for Japanese Anaplastic or Medullary Thyroid Carcinoma Patients
Status: COMPLETED
Conditions: Thyroid Carcinoma
Interventions: DRUG: Sorafenib (Nexavar,BAY43-9006)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of ActiGraft Pro Compared to Standard of Care in DFUs
Status: COMPLETED
Conditions: Diabetic Foot|Chronic Ulcer
Interventions: DEVICE: ActiGraft|DEVICE: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Long-lasting Adaptation to Endurance and Speed-power Training on Plasma Free Amino Acids Concentration
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Athletes Aged 18-35 Years
Interventions: BEHAVIORAL: Sprint training|BEHAVIORAL: Endurance training|BEHAVIORAL: Recreational Training
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Confirmatory Study of BK1310 in Healthy Infants
Status: COMPLETED
Conditions: Tetanus|Diphtheria|Pertussis|Poliomyelitis|Bacterial Meningitis
Interventions: BIOLOGICAL: DPT-IPV-Hib|BIOLOGICAL: Hib vaccine|BIOLOGICAL: DPT-IPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Encapsulated Flavour Effects on Satiety
Status: COMPLETED
Conditions: Overweight
Interventions: OTHER: Control gummy with free flavour (without encapsulating)|OTHER: Experimental gummy with 50% free/50% encapsulated flavour|OTHER: Experimental gummy with 100% encapsulated flavour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Somatosensory Profiling in Radicular Pain Patients And it's Correlation With Treatment Outcome
Status: COMPLETED
Conditions: Radiculopathy|Lower Extremity Radicular Pain
Interventions: DEVICE: Quantitative Sensory Testing (QST)|PROCEDURE: Epidural Steroid Injection (ESI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the GlucoTrack, Non-Invasive Glucose Monitoring Device
Status: UNKNOWN
Conditions: Type 1 Diabetes Mellitus|Type 2 Diabetes Mellitus|Gestational Diabetes
Interventions: DEVICE: GlucoTrack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial of Transdiagnostic Cognitive-Behavior Therapy for Anxiety Disorders
Status: COMPLETED
Conditions: Panic Disorder|Agoraphobia|Social Anxiety Disorder|Generalized Anxiety Disorder
Interventions: BEHAVIORAL: Transdiagnostic Cognitive-Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Compare Automated Lyumjev Delivery With Carbohydrate Counting, Qualitative Meal-size Estimation, and Meal Detection in Type 1 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1|Type 1 Diabetes
Interventions: COMBINATION_PRODUCT: Hybrid automated Lyumjev delivery system with carbohydrate counting|COMBINATION_PRODUCT: Hybrid automated Lyumjev delivery system with meal size estimation|COMBINATION_PRODUCT: Fully automated Lyumjev delivery system with meal detection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Glembatumumab Vedotin, Nivolumab, and Ipilimumab in Treating Patients With Advanced Metastatic Solid Tumors That Cannot Be Removed by Surgery
Status: WITHDRAWN
Conditions: Advanced Malignant Solid Neoplasm|Estrogen Receptor Negative|GPNMB Positive|HER2/Neu Negative|Metastatic Malignant Solid Neoplasm|Metastatic Melanoma|Progesterone Receptor Negative|Stage III Breast Cancer AJCC v7|Stage III Cutaneous Melanoma AJCC v7|Stage III Uveal Melanoma AJCC v7|Stage IIIA Cutaneous Melanoma AJCC v7|Stage IIIB Cutaneous Melanoma AJCC v7|Stage IIIC Cutaneous Melanoma AJCC v7|Stage IV Breast Cancer AJCC v6 and v7|Stage IV Cutaneous Melanoma AJCC v6 and v7|Stage IV Uveal Melanoma AJCC v7|Triple-Negative Breast Carcinoma|Unresectable Solid Neoplasm
Interventions: DRUG: Glembatumumab Vedotin|BIOLOGICAL: Ipilimumab|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aortic Compression Trial to Reduce Blood Loss at Cesarean Section
Status: ENROLLING_BY_INVITATION
Conditions: Post Partum Hemorrhage|Cesarean Section Complications|Anemia
Interventions: PROCEDURE: External aortic compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacodynamics Study of Enoxalow Compared to Clexane in Healthy Subjects After Subcutaneous Single Dose
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Heparin, Low-Molecular-Weight
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iodine I 131 Ethiodized Oil in Preventing Recurrent Cancer in Patients Who Have Undergone Treatment for Liver Cancer
Status: COMPLETED
Conditions: Liver Cancer
Interventions: DRUG: ethiodized oil|RADIATION: iodine I 131 ethiodized oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: CDC-9 Inactivated Rotavirus Vaccine (IRV) Intramuscular (IM) Phase 1 Clinical Trial in Healthy Adults
Status: RECRUITING
Conditions: Rotavirus Infections
Interventions: BIOLOGICAL: 3.75 µg Dose of CDC-9 Inactivated Rotavirus Vaccine (IRV)|BIOLOGICAL: 7.5 µg Dose of CDC-9 Inactivated Rotavirus Vaccine (IRV)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tislelizumab in Combination With Sitravatinib in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Tislelizumab|DRUG: Docetaxel|DRUG: Sitravatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cynara Scolymus Extract for Treatment of Diabetes Mellitus Type 2
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: Cynara Scolymus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Composite-ceramic Implant-supported Posterior Crowns (Cerasmart)
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Materials
Interventions: PROCEDURE: composite-ceramic|PROCEDURE: Monolithic zirconia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Teleconsultation in Counter-reference Between Tertiary and Primary Care for Patients With Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: OTHER: Teleconsultation|OTHER: Hospital (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Alloreactive NK Cells for Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Leukemia
Interventions: DRUG: Thymoglobulin|DRUG: Busulfan|DRUG: Fludarabine|PROCEDURE: Alloreactive NK Infusion|DRUG: G-CSF|DRUG: Tacrolimus|DRUG: Methotrexate|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ChAracterization of Normal and Pathological moRphological Variations of the TEMporomandibular Joint by Real-time magnetIc reSonance Imaging
Status: NOT_YET_RECRUITING
Conditions: Healthy|Temporomandibular Joint Disorders
Interventions: DEVICE: MRI with Real Time MRI Rapid Flash sequence
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of a 35 mg Delayed Release Formulation of Risedronate for Osteoporosis
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: risedronate|DRUG: risedronate|DRUG: risedronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant PD-1 Inhibitor Combined With Cetuximab in Operable Locally Advanced HNSCC
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma|Neoadjuvant Therapy
Interventions: DRUG: 3cycles (Toripalimab + cetuximab)|PROCEDURE: Surgery|RADIATION: Radiotherapy or chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Intrathecal Enzyme Therapy for Cognitive Decline in MPS I
Status: COMPLETED
Conditions: Cognitive Decline|Mucopolysaccharidosis I|Hurler-Scheie Syndrome|Scheie Syndrome|Lysosomal Storage Disease
Interventions: DRUG: laronidase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Restoration of Permanent Molars Affected With (MIH) Using Composite Restorations or Preformed Metal Crowns
Status: COMPLETED
Conditions: Molar Incisor Hypomineralization
Interventions: PROCEDURE: Direct composite restorations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety/Efficacy Study of Subcutaneously Injected Prandial Insulins Compared to Insulin Lispro Alone in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type II
Interventions: DRUG: Insulin lispro|DRUG: Insulin aspart|DRUG: Recombinant human hyaluronidase PH20|DRUG: Insulin glulisine|DRUG: Insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Low Dose Interleukin 2 (IL-2) Plus PEG-IFN/RBV In Chronic Hepatitis C Virus Genotype I
Status: TERMINATED
Conditions: Hepatitis C
Interventions: BIOLOGICAL: Interleukin 2|DRUG: Ribavirin|BIOLOGICAL: Pegylated Interferon Alpha|BIOLOGICAL: Inteleukin-2|DRUG: Ribavirin + Pegylated interferon-alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: WIReD: Wireless Interstage Remote Device Study
Status: ENROLLING_BY_INVITATION
Conditions: Congenital Heart Disease in Children|Vital Signs|Pediatrics|Remote Monitoring
Interventions: DEVICE: Gabi SmartCare Pediarity System [Gabi Band, Gabi Monitor App, Gabi Analytics]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Counselling and Visual Aid on Anxiety in Endoscopic Patients
Status: COMPLETED
Conditions: Chronic Liver Disease|Inflammatory Bowel Diseases
Interventions: BEHAVIORAL: Counselling with visual aid|BEHAVIORAL: Counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immune Checkpoint Inhibition With Lurbinectedin Relapsed/Recurrent SCLC
Status: TERMINATED
Conditions: Small-cell Lung Cancer|Relapsed Small Cell Lung Cancer|Recurrent Small Cell Lung Cancer
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|DRUG: Lurbinectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Protection of Preoperative Ondansetron 15 Minutes Before Spinal Anaesthesia in Caesarean Section
Status: COMPLETED
Conditions: Hypotension|Nausea|Vomiting
Interventions: DRUG: Ondansetron|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Challenge Meditech 082 (CM082) Tablets in Patients With Advanced Malignant Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Tumors
Interventions: DRUG: CM082
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Study of Refeeding to Optimize iNpatient Gains
Status: ENROLLING_BY_INVITATION
Conditions: Atypical Anorexia Nervosa
Interventions: OTHER: Individualized Caloric Refeeding (ICR)|OTHER: Higher Calorie Refeeding (HCR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Intraperitoneal Hyperthermic Chemotherapy
Status: UNKNOWN
Conditions: Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Cancer|Uterine Cancer|Mesotheliomas|Gastrointestinal Cancers|Cervical Cancer
Interventions: DEVICE: HIPEC: MMC 30mg @ T0, 10mg @ T45min|DEVICE: HIPEC: MMC + CDDP 30mg @ T0, 10mg @ T45min 50 mg/m2 @T0|DEVICE: HIPEC: CDDP 75 mg/m2 @T0|DEVICE: HIPEC: CDDP+ Doxorubicin 50 mg/m2 @T0 15 mg/m2 @T0
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of NovoSeven® in Bleeding Prophylaxis in Hemophilia
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A With Inhibitors|Haemophilia B With Inhibitors
Interventions: DRUG: activated recombinant human factor VII
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Mode of Administration of Soluble Fibre Blend on Glycemia, Appetite & Sensory Parameters
Status: UNKNOWN
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Soluble viscous fibre blend powder in hydrophobic matrix|DIETARY_SUPPLEMENT: Soluble viscous fibre blend in pre hydrated form|DIETARY_SUPPLEMENT: No soluble viscous fibre blend|DIETARY_SUPPLEMENT: Soluble viscous fibre blend premixed with ½ carbohydrate gel|DIETARY_SUPPLEMENT: No soluble viscous fibre blend, ½ carbohydrate jello
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: N-Acetyl Cysteine in the Prevention of Contrast Induced Nephropathy in Cirrhosis of Liver-NEPHRO Trial
Status: COMPLETED
Conditions: Liver Cirrhoses
Interventions: DRUG: N-Acetyl Cysteine|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Once Daily Low Dose and High Dose Solabegron or Placebo Given for 12 Weeks to Treat Women With Symptoms of Overactive Bladder: Sudden Urge to Urinate, Frequent Urination Associated With Wetting Episodes (VEL-2001)
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Solabegron modified release tablets, low dose|DRUG: Solabegron modified release tablets, high dose|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Avatar-mediated Therapy Versus Cognitive Behavioural Therapy for Persisting Experiences of Hearing Voices
Status: RECRUITING
Conditions: Auditory Hallucination|Psychotic Disorders|Schizophrenia and Related Disorders
Interventions: BEHAVIORAL: Avatar therapy|BEHAVIORAL: Cognitive behavioural therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors
Status: COMPLETED
Conditions: Diffuse Astrocytoma|Anaplastic Astrocytoma|Astrocytoma|Oligodendroglioma, Childhood|Anaplastic Oligodendroglioma|Glioblastoma|Pilocytic Astrocytoma|Giant Cell Astrocytoma|Pleomorphic Xanthoastrocytoma|Anaplastic Pleomorphic Xanthoastrocytoma|Angiocentric Glioma|Chordoid Glioma of Third Ventricle|Gangliocytoma|Ganglioglioma|Anaplastic Ganglioglioma|Dysplastic Gangliocytoma of Cerebrellum|Desmoplastic Infantile Astrocytoma and Ganglioglioma|Papillary Glioneuronal Tumor|Rosette-forming Glioneurona Tumor|Central Neurocytoma|Extraventricular Neurocytoma|Cerebellar Iponeurocytoma
Interventions: DRUG: Dabrafenib|DRUG: trametinib|DRUG: Carboplatin|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Mobile Application for Caregivers of Patients With Percutaneous Endoscopic Gastrostomy (PEG) on Caregivers
Status: COMPLETED
Conditions: Percutaneous Endoscopic Gastrostomy|Caregiver Burden|Mobile Application
Interventions: OTHER: mobile application ( PEG Assist )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Hyaluronic Acid Pulpotomies in Primary Molars
Status: COMPLETED
Conditions: Pulpitis
Interventions: PROCEDURE: Hyaluronic acid: Gengigel teething|PROCEDURE: Formocresol Buckley formula: Formacresol|PROCEDURE: Ferric sulfate: ViscoStat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Transcranial Direct-current Stimulation in Eating Behavior of Women With Fibromyalgia
Status: UNKNOWN
Conditions: Fibromyalgia|Food Addiction
Interventions: DEVICE: Sham transcranial direct current stimulation (tDCS)|DEVICE: Active transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of BV-araU in the Treatment of Varicella-Zoster Viral Disease (VZV) in HIV-Infected Children Who Have Not Had Success With or Who Cannot Take Other Treatments for VZV
Status: COMPLETED
Conditions: HIV Infections|Chickenpox
Interventions: DRUG: Sorivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to a Malaria Vaccine (MSP1 42-C1) With or Without CPG 7909 Adjuvant
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: MSP1 42-C1/Alhydrogel|BIOLOGICAL: CPG 7909
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Helping Poor Smokers Quit
Status: COMPLETED
Conditions: Smoking Cessation|Smoking, Tobacco|Smoking, Cigarette|Smoking, Pipe|Smoking (Tobacco) Addiction|Smoking|Tobacco Use|Tobacco Dependence|Tobacco Use Cessation|Tobacco Smoking|Tobacco; Use, Rehabilitation|Nicotine Dependence|Nicotine Use Disorder|Nicotine Dependence, Cigarettes|Nicotine Dependence Tobacco Product
Interventions: BEHAVIORAL: Specialized Quitline|BEHAVIORAL: Basic Needs Navigator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Long-term Efficacy and Safety of AK102 in Patients With Hyperlipidemia
Status: UNKNOWN
Conditions: Hyperlipidemia
Interventions: BIOLOGICAL: AK102|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Xanthohumol as an Adjuvant in the Treatment of Septic Shock
Status: RECRUITING
Conditions: Septic Shock|Pneumonia|ARDS
Interventions: DIETARY_SUPPLEMENT: Xanthohumol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-Human, Phase 1b/2a Trial of a Multipeptide Therapeutic Vaccine in Patients With Progressive Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma, Adult
Interventions: BIOLOGICAL: Multiple dose of EO2401
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Infertility by Collagen Scaffold Loaded With Autologous Bone Marrow Stem Cells
Status: UNKNOWN
Conditions: Infertility|Intrauterine Adhesions|Endometrial Dysplasia
Interventions: PROCEDURE: autologous bone marrow stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Using Swedish Registries to Find Out How Many People With Type 2 Diabetes Had Cardiovascular Disease and Started Treatment With Empagliflozin Between 2015 and 2017
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Empagliflozin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Repeated Administration of Eslicarbazepine Acetate on the Pharmacokinetics of Simvastatin in Healthy Subjects
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Eslicarbazepine acetate|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study With Palonosetron Alone in Preventing Chemotherapy-induced Nausea and Vomiting in Untreated Patients With Aggressive Non Hodgkin's Lymphomas Who Underwent Moderately Emetogenic Chemotherapy
Status: COMPLETED
Conditions: Chemotherapy-Induced Nausea and Vomiting|Non Hodgkin's Lymphoma
Interventions: DRUG: Palonosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lactobacillus Plantarum DR7 for Gut-Brain-Axis Benefits
Status: COMPLETED
Conditions: Stress
Interventions: DIETARY_SUPPLEMENT: Lactobacillus plantarum DR7|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Learn How Different Forms of The Study Medicine Called Danuglipron Are Taken up Into the Blood In Healthy Adults
Status: RECRUITING
Conditions: Healthy Participants|Healthy Subjects
Interventions: DRUG: Danuglipron
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: IM83 Clinical Study of CAR-T Cell Therapy in Patients With Relapsed or Refractory Osteosarcoma
Status: NOT_YET_RECRUITING
Conditions: Refractory Osteosarcoma|Recurrent Osteosarcoma
Interventions: BIOLOGICAL: IM83 CAR-T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Toripalimab and Anlotinib Combination Treatment in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma After Failure of at Least One Line of Platinum-Based Chemotherapy (TORAL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Nasopharyngeal Carcinoma|Recurrent or Metastatic Nasopharyngeal Carcinoma
Interventions: DRUG: Toripalimab and Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact in the Medical Care Among the Rheumatic Diseases Patients in a Hospital in México During COVID-19 Pandemic
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Quality of Life
Interventions: OTHER: COVID-19 survey|OTHER: RAPID-3|OTHER: WHOQOL-BREF|OTHER: DASS-21 instrument (depression and anxiety)|OTHER: IER-R (posttraumatic stress)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomised, Open-Label Study to Evaluate the Relative and Absolute Bioavailability of Cotadutide in Healthy Subjects
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis|Type 2 Diabetes Mellitus (T2DM)|Chronic Kidney Disease
Interventions: DRUG: cotadutide solution for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of the Small Intestine Microbiome Aspiration (SIMBA) Capsule
Status: COMPLETED
Conditions: Proof of Concept|Irritable Bowel Syndrome
Interventions: DEVICE: Ingestible capsule|PROCEDURE: Sedated EGD|DIAGNOSTIC_TEST: Lactulose Breath Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC