pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: CIFN and IFN γ-1b With or Without Ribavirin for Treatment of Chronic Hepatitis C (Nonresponders)
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Consensus Interferon-Alpha, Interferon Gamma-1b, Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Change in Patient Experience in Adult Participants With Chronic Lymphocytic Leukemia (CLL) Receiving Oral Venetoclax Tablets + Intravenous Rituximab or Bruton's Tyrosine Kinase Inhibitors Tablets in the United Kingdom
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Candesartan Cilexetil Plus Hydrochlorothiazide in Subjects With Severe Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Candesartan cilexetil and hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: XIENCE V® Everolimus Eluting Coronary Stent System USA Post-Approval Study (XIENCE V® USA Long Term Follow-up Cohort)
Status: COMPLETED
Conditions: Chronic Coronary Occlusion|Vascular Disease|Myocardial Ischemia|Coronary Artery Stenosis|Coronary Disease|Coronary Artery Disease|Coronary Restenosis
Interventions: DEVICE: XIENCE V® EECSS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Tarceva (Erlotinib) or Placebo in Combination With Platinum-Based Therapy as First Line Treatment in Patients With Advanced or Recurrent Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: Placebo|DRUG: Platinum chemotherapy (cisplatin or carboplatin)|DRUG: erlotinib [Tarceva]|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine Patient-Controlled Analgesia for Acute Pain
Status: TERMINATED
Conditions: Acute Pain|Multiple Trauma|Fractures
Interventions: DRUG: Ketamine|DRUG: Hydromorphone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Glycemic Control of CKD-501 in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: CKD-501 0.5mg|DRUG: CKD-501 1mg|DRUG: CKD-501 2mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pimecrolimus and Epidermal Barrier Function
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: cream treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Efficacy and Safety of Hyaluronic Acid Vaginal Gel to Ease Vaginal Dryness
Status: COMPLETED
Conditions: The Primary Objective of This Study Was to Assess the Efficacy and Safety of Hyaluronic Acid Vaginal Gel in Treating Vaginal Dryness
Interventions: DEVICE: Hyalofemme|DEVICE: Estriol cream (Ovestin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RACIN in Patients With Advanced TIL-negative Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor, Adult
Interventions: COMBINATION_PRODUCT: Low dose irradiation + Nivolumab + Ipilimumab or Cyclophosphamide + Aspirin/Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anaplerotic Therapy in Propionic Acidemia
Status: COMPLETED
Conditions: Propionic Acidemia
Interventions: DRUG: ornithine alpha ketoglutarate|DRUG: glutamine|DRUG: disodium citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAD/CAM Fixed Retainers vs. Conventional Multistranded Fixed Retainers in Orthodontic Patients. Comparison of Stability, Retainer Failure Rate, Adverse Effects, Cost-effectiveness, and Patient Satisfaction. A Randomized Controlled Clinical Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapse
Interventions: OTHER: Bonding of either CAD/CAM or conventional multistranded stainless steel fixed retainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Sitagliptin on Short-Term Metabolic Dysregulation of Oral Glucocorticoid Therapy
Status: COMPLETED
Conditions: Pre-diabetes|Impaired Fasting Glucose|Impaired Glucose Tolerance
Interventions: DRUG: Dexamethasone 2.5 mg and Sitagliptin 100 mg|DRUG: Dexamethasone 2.5 mg and placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Monitoring Strategies for the Detection of Atrial Fibrillation in Patients With Cryptogenic Stroke
Status: TERMINATED
Conditions: Stroke|Atrial Fibrillation
Interventions: DIAGNOSTIC_TEST: 7-day electrocardiographic monitoring|DIAGNOSTIC_TEST: 48-hr electrocardiographic monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tele Nursing Application For Type 1 Diabetes Mellitus Adolescents
Status: COMPLETED
Conditions: Telenursing|Adolescent|Type 1 Diabetes Mellitus
Interventions: BEHAVIORAL: educational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate Two Formulations of Carisoprodol in Subjects With Musculoskeletal Spasm of the Lower Back
Status: COMPLETED
Conditions: Lower Back Pain
Interventions: DRUG: Carisoprodol SR 700 mg|DRUG: Carisoprodol SR 500 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Safety Video on Ski and Snowboard School Program Participants in Calgary, Alberta
Status: UNKNOWN
Conditions: Knowledge, Attitudes, Practice|Risk Behavior|Injuries
Interventions: OTHER: Ski and Snowboard Safety Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multicenter Study of the Safety and Efficacy of Dermal Filler, Belotero® Soft
Status: COMPLETED
Conditions: Facial Wrinkles
Interventions: DEVICE: CosmoDerm1|DEVICE: Belotero Soft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Vasopressin, Methylprednisolone, and Epinephrine for Inhospital Cardiac Arrest
Status: COMPLETED
Conditions: Heart Arrest
Interventions: DRUG: Vasopressin, Epinephrine, and Steroids|DRUG: Placebo, Epinephrine, Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lipiflow Treatment Alone vs. Lipiflow + Dextenza Treatment for Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: PROCEDURE: LipiFlow Thermal Pulsation|DRUG: Dexamethasone Intracanalicular Insert, 0.4mg with LipiFlow Thermal Pulsation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Cadonilimab Injection in Combination With Regorafenib for the Advanced Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Advanced Hepatocellular Carcinoma That Has Failed at Least One Prior Systemic Therapy
Interventions: DRUG: Cadonilimab Injection|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glycopyrrolate/Formoterol Fumarate MDI Compared With Spiriva® as An Active Control in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: PT003|DRUG: PT001|DRUG: PT005|DRUG: Tiotropium inhalation powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Two-arm Study of Fertility in Men With COVID-19
Status: UNKNOWN
Conditions: Covid19|Fertility Issues
Interventions: DIAGNOSTIC_TEST: Sperm test|DIAGNOSTIC_TEST: hormone levels (testosterone, FSH, LH, prolactin)|DIAGNOSTIC_TEST: SARS-CoV-2 Ig G levels|OTHER: Testis pathology samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chronic Hepatitis B Patients With Concurrent MAFLD: Cohort Study and Exercise Intervention.
Status: ENROLLING_BY_INVITATION
Conditions: Chronic Hepatitis B|Non-alcoholic Fatty Liver Disease
Interventions: OTHER: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Bone Marrow Derived Stem Cells on Patients With Cutaneous Photoaging
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Effect of Ultraviolet Radiation on Photoaged Skin|Dermatologic Disorders
Interventions: BIOLOGICAL: Allogeneic Mesenchymal Bone Marrow Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CLL-1/CD33 Targeted LCAR-AMDR Cells in Patients With Relapsed or Refractory Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: LCAR-AMDR Cells Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Thoracic Peri-Operative Integrative Surgical Care Evaluation (POISE) Trial- Stage I
Status: COMPLETED
Conditions: Lung Neoplasms|Esophageal Neoplasms|Stomach Neoplasms
Interventions: OTHER: Integrative Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bleomycin Infusion (MMP®) to Repigment Achromic Scars
Status: UNKNOWN
Conditions: SCAR
Interventions: DRUG: Bleomycin|OTHER: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endometrial Preparation in Frozen Embryo Transfer Cycles
Status: UNKNOWN
Conditions: Reproductive Behavior
Interventions: PROCEDURE: endometrial preparation for frozen blastocyst transfer|DRUG: Letrozole|DRUG: Ovidrel|DRUG: Estrofem|DRUG: Endometrin 100Mg Vaginal Insert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial of 8 Weeks Pulmonary Rehabilitation in Advanced Stage Lung Cancer Patients With COPD During Cytotoxic Chemotherapy
Status: UNKNOWN
Conditions: COPD|Lung Cancer
Interventions: BEHAVIORAL: pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Identify a Biomarker Predictive for Response on Everolimus in Solid Tumors (CPCT-03)
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Effectiveness and Safety Study of Intravenous Golimumab in Patients With Active Rheumatoid Arthritis Despite Treatment With Methotrexate Therapy
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Golimumab|OTHER: Placebo|DRUG: methotrexate (MTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Recombinant Mycobacterium Tuberculosis Fusion Protein for 65-year-olds and Above
Status: RECRUITING
Conditions: Latent Tuberculosis Infection
Interventions: BIOLOGICAL: Recombinant Mycobacterium Tuberculosis Fusion Protein|BIOLOGICAL: Purified Protein Derivative of Tuberculin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Kabul Vitamin D Supplementation Trial
Status: UNKNOWN
Conditions: Pneumonia|Vitamin D Deficiency
Interventions: DRUG: vitamin D|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Arthrocentesis by Injection of Ringer With or Without Corticosteroid in Treatment of Internal Derangement
Status: COMPLETED
Conditions: Temporomandibular Joint Dysfunction|Pain|Arthrocentesis
Interventions: DRUG: ringer with corticosteroid|DRUG: ringer without corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Strategies for Endotracheal Tube Cuff Underinflation Prevention During Invasive Mechanical Ventilation
Status: COMPLETED
Conditions: Acute Brain Injury|Brain Injuries
Interventions: DEVICE: Tracoe Smart CuffmanagerTM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trial to Assess Parkinson's Disease (PD) Symptom Control to Four Doses of Rotigotine in a Transdermal Patch
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Rotigotine|DRUG: Rotigotine|OTHER: Placebo|DRUG: Rotigotine|DRUG: Rotigotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Interrupting Sedentary Behavior With High - or Low Intensity PA on CVD - and Cardiometabolic Riskfactors, and Cognitive Performance.
Status: ENROLLING_BY_INVITATION
Conditions: Sedentary Behavior|Physical Activity
Interventions: BEHAVIORAL: Sedentary behavior
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Feasibility and Acceptability of Utilizing Telehealth for Increasing Access to Bariatric Surgery
Status: RECRUITING
Conditions: Telehealth|Face-2-Face (F2F)
Interventions: BEHAVIORAL: Telehealth|BEHAVIORAL: In Person (Face-2-Face)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Ability of the Vaccine to Induce Antibodies Against the Respiratory Syncytial Virus in Healthy Adults
Status: COMPLETED
Conditions: Respiratory Syncytial Virus (RSV)
Interventions: BIOLOGICAL: RSV F subunit 45 μg No adjuvant|BIOLOGICAL: RSV F subunit 45 μg Aluminum hydroxide adjuvant|BIOLOGICAL: RSV F subunit 45 μg MF59 adjuvant|BIOLOGICAL: RSV F subunit 90 μg No adjuvant|BIOLOGICAL: RSV F subunit 90 μg Aluminum hydroxide adjuvant|BIOLOGICAL: RSV F subunit 90 μg MF59 adjuvant|BIOLOGICAL: RSV F subunit 135 μg No adjuvant|BIOLOGICAL: RSV F subunit 135 μg Aluminum hydroxide adjuvant|BIOLOGICAL: RSV F subunit 135 μg MF59 adjuvant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Tocilizumab Plus Dexamethasone vs. Dexamethasone for Patients With Covid-19
Status: COMPLETED
Conditions: Coronavirus Infection|SARS (Severe Acute Respiratory Syndrome)|Virus Diseases|Coronaviridae Infections|Nidovirales Infections|RNA Virus Infections|Respiratory Tract Infections|Respiratory Tract Disease
Interventions: DRUG: Tocilizumab|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Dose of Irbesartan for Renoprotection in Type 2 Diabetic Patients With Persistent Microalbuminuria
Status: COMPLETED
Conditions: Type 2 Diabetes|Microalbuminuria
Interventions: DRUG: irbesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Versus Mg Added to Bupivacaine Used in ESPB for Perioperative Pain Control in Patients Undergoing Unilateral Nephrectomy
Status: RECRUITING
Conditions: Renal Neoplasm
Interventions: PROCEDURE: ultrasound guided Erector Spinae Plane Block using 27ml bupivacaine 0.25%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase III Study to Assess the Long Term Efficacy, Carry-over Effect and Safety of 300 IR Sublingual Immunotherapy Tablets
Status: COMPLETED
Conditions: Allergy
Interventions: DRUG: 300 IR (4M)|DRUG: 300 IR (2M)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Epidemiology and Treatment Strategy of Open Respiratory Phenotype in Critically Ill Patients
Status: RECRUITING
Conditions: Mechanical Ventilation Pressure High|Critical Illness
Interventions: OTHER: pressure-volume curve with a low-flow insufflation of 5 L/min
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of Bifocal and Prismatic Bifocal Spectacles for Myopia Control in Children
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Bifocal spectacles|DEVICE: Prismatic bifocal spectacles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Formoterol Certihaler, Tiotropium HandiHaler and Tiotropium HandiHaler in Combination With Formoterol Certihaler in Patients With Stable Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Sarcopenia Improves the Muscle Mass and Muscle Strength of Patients With Liver Cirrhosis-Child C
Status: ACTIVE_NOT_RECRUITING
Conditions: Liver Cirrhosis
Interventions: DRUG: Branched chain amino acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Phase I/II Clinical Study of PT-112 in Combination With Docetaxel in Subjects With Advanced Solid Tumor in a Phase I Dose Escalation Study and in Subjects With Non-Small Cell Lung Cancer (NSCLC) in a Phase II Dose Confirmation Study
Status: UNKNOWN
Conditions: Advanced Solid Tumor|Non-Small Cell Lung Cancer
Interventions: DRUG: PT-112|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: White Button Mushroom Sup for the Reduction of PSA in Pts With Biochemically Rec or Therapy Naive Fav Risk Prostate CA
Status: RECRUITING
Conditions: Prostate Adenocarcinoma|PSA Failure|PSA Progression|Recurrent Prostate Carcinoma|Stage I Prostate Cancer AJCC v8|Stage IIA Prostate Cancer AJCC v8|Stage IIB Prostate Cancer AJCC v8|Stage IIC Prostate Cancer AJCC v8|Stage IIIA Prostate Cancer AJCC v8|Stage IIIC Prostate Cancer AJCC v8
Interventions: OTHER: Clinical Observation|OTHER: Patient Observation|OTHER: Questionnaire Administration|DRUG: White Button Mushroom Extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can we Improve Preoxygenation by Using Adjustable Pressure Limiting Valve (APL) ?
Status: COMPLETED
Conditions: Preoxygenation
Interventions: PROCEDURE: preoxygenation with 100% O2, fresh gas flow rate 12 L/minute
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: US Study of UM171-Expanded CB in Patients With High Risk Leukemia/Myelodysplasia
Status: ACTIVE_NOT_RECRUITING
Conditions: High Risk Hematological Malignancy|Cord Blood Transplant
Interventions: BIOLOGICAL: ECT-001-CB (UM171-Expanded Cord Blood Transplant)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Subcutaneous Heparin and Enoxaparin for Deep Venous Thrombosis (DVT) Prophylaxis in Surgical Intensive Care Patients
Status: WITHDRAWN
Conditions: Lower Extremity Deep Venous Thrombosis
Interventions: DRUG: heparin|DRUG: enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Posaconazole for the Prevention of Influenza-associated Aspergillosis in Critically Ill Patients
Status: COMPLETED
Conditions: Aspergillosis; Pulmonary, Invasive (Etiology)
Interventions: DRUG: SOC +Posaconazole 18 MG/ML (milligram/milliliter)|OTHER: standard of care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Brachytherapy With Durvalumab or Tremelimumab for the Treatment of Patients With Platinum-Resistant, Refractory, Recurrent, or Metastatic Gynecological Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Malignant Female Reproductive System Neoplasm|Platinum-Resistant Malignant Female Reproductive System Neoplasm|Recurrent Malignant Female Reproductive System Neoplasm|Refractory Malignant Female Reproductive System Neoplasm
Interventions: BIOLOGICAL: Durvalumab|RADIATION: Internal Radiation Therapy|BIOLOGICAL: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Conversion From Peginesatide to Epoetin Alfa in Patients Receiving Hemodialysis
Status: TERMINATED
Conditions: Anemia
Interventions: DRUG: Peginesatide|DRUG: Epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Sintilimab Combined With IBI305 in Patients With Advanced Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: Sintilimab+IBI305
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiopathological Study and Pharmacological Modulation of Cutaneous Atrophy's Markers Induced by Glucocorticoids
Status: UNKNOWN
Conditions: Cortico Atrophy
Interventions: DRUG: RV3391A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Online Psychosocial Intervention for Nursing Students Who Experienced Intimate Partner Abuse in Turkey
Status: COMPLETED
Conditions: Violence, Sexual|Violence, Physical|Violence, Gender-Based|Violence|Post Traumatic Stress Disorder|Post Traumatic Growth, Psychological
Interventions: BEHAVIORAL: The internet-based psychosocial intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Interest of the Induction With Target-controlled Inhalation of Sevoflurane on Spikes Wave Occurrence
Status: COMPLETED
Conditions: General Anesthesia
Interventions: DRUG: Induction with Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Endoscopic Ultrasound-guided Celiac Plexus Neurolysis (EUS-CPN)With Alcohol in Unresectable Pancreatic Cancer: a Pilot Study
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: dehydrated alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis
Status: RECRUITING
Conditions: Eosinophilic Granulomatosis With Polyangiitis (EGPA)|Churg-Strauss Syndrome (CSS)|Giant Cell Arteritis|Granulomatosis With Polyangiitis|Microscopic Polyangiitis|Polyarteritis Nodosa|Takayasu Arteritis
Interventions: DRUG: Naltrexone Hydrochloride|OTHER: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Efficacy and Safety of Combination of Diacerein and Celecoxib Administered in Patients With Knee OA
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DRUG: Diacerein|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of Hot Versus Cold Snare Polypectomy of Small Colorectal Polyps
Status: COMPLETED
Conditions: Colonic Polyps|Colorectal Neoplasms|Adenoma
Interventions: PROCEDURE: Polypectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Symbicort® and Prednisolone in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: budesonide/formoterol|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Immune Responses of Trivalent Cold-Adapted Influenza Vaccine (CAIV-T) Compared With (TIV)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: CAIV-T|OTHER: TIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Profile Matching: A Precision Medicine Approach to Concussion Rehabilitation
Status: COMPLETED
Conditions: Mild Traumatic Brain Injury
Interventions: BEHAVIORAL: Graded exposure therapy|BEHAVIORAL: Pacing + mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ibuprofen Bioavailability Study
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Test - RB ibuprofen acid orodispersible tablets|DRUG: Reference - RB Nurofen ibuprofen acid tablets|DRUG: Comparator - Dolormin ibuprofen lysine tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Backward Running on a Negative Slope as a Treatment for Achilles Tendinopathy in Runners
Status: COMPLETED
Conditions: Achilles Tendinopathy
Interventions: PROCEDURE: Backwards running on a Treadmil with a negative slope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lixisenatide in Patients With Type 2 Diabetes Mellitus Insufficiently Controlled by Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Lixisenatide (AVE0010)|DRUG: Placebo|DEVICE: Pen auto-injector|DRUG: Metformin|DRUG: Sulfonylurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hepaticojejunostomy With or Without Permanent Duodenal Access Loop in Treatment of Iatrogenic Bile Ducts Injuries, a Comparative Study
Status: COMPLETED
Conditions: Iatrogenic Bile Duct Injuries|Duodenojejunostomy Access Loop
Interventions: PROCEDURE: duodenojejunostomy access loop|PROCEDURE: hepaticojejunostomy without access loop
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Allow Access to Single Agent Panobinostat for Patients Who Are on s.a. Panobinostat Treatment in a Novartis-sponsored Study and Continue to Benefit From the Treatment as Judged by the Investigator
Status: COMPLETED
Conditions: Hematologic Neoplasms
Interventions: DRUG: Panobinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Cabazitaxel Versus Weekly Paclitaxel as Neo-adjuvant Treatment in Patients With Triple Negative or Luminal B/HER2 Normal BC (GENEVIEVE)
Status: COMPLETED
Conditions: Primary Breast Cancer
Interventions: DRUG: Cabacitaxel|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skeletal Muscle Response to Amino Acids and Load Carriage Exercise
Status: COMPLETED
Conditions: Muscle Loss|Muscle Anabolism|Muscle Performance
Interventions: OTHER: Leucine-enriched nutritional supplement|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Prurisol Administered Orally for Active Mild to Moderate Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Prurisol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Closed-loop tDCS in Patients in Minimally Conscious State
Status: RECRUITING
Conditions: Minimally Conscious State
Interventions: DEVICE: Anodal transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Neoadjuvant Chemotherapy Plus Nivolumab Versus Neoadjuvant Chemotherapy Plus Placebo, Followed by Surgical Removal and Adjuvant Treatment With Nivolumab or Placebo for Participants With Surgically Removable Early Stage Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: BIOLOGICAL: Nivolumab|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Paclitaxel|DRUG: Pemetrexed|DRUG: Placebo|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimization of Initial Energy for Cardioversion of Atrial Fibrillation With Biphasic Shocks
Status: UNKNOWN
Conditions: Atrial Fibrillation|Cardioversion
Interventions: PROCEDURE: 100 joule as first biphasic shock energy|PROCEDURE: 120 joule as first biphasic shock energy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Necessity of Fusion Following Decompression Surgery in Patients With Single-level Lumbar Stenosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Lumbar Spinal Stenosis|Spinal Stenosis|Spinal Fusion
Interventions: PROCEDURE: decompression|PROCEDURE: fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MAGIK for Femoral/Tibial Shaft Fractures
Status: NOT_YET_RECRUITING
Conditions: Femoral Shaft Fracture|Tibial Shaft Fracture
Interventions: DRUG: GIK solution|DRUG: Isotonic Normal Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiologic Pathologic Correlation of Imaging to Distinguish True Progression From Pseudoprogression in Brain Malignancies
Status: RECRUITING
Conditions: Brain Malignancies|Pseudoprogression
Interventions: PROCEDURE: MRI Scan|PROCEDURE: CT Scan|PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Acute Response of Iloprost Inhalation Using the Breelib Nebulizer in Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Hypertension|Pulmonary Arterial Hypertension
Interventions: DRUG: Iloprost
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect on Tear Functions of Pretarsal and Preseptal Techniques of Botulinum Toxin Type A Injection in Hemifacial Spasm
Status: UNKNOWN
Conditions: Hemifacial Spasm
Interventions: DRUG: preseptal injection of botulinum toxin type A|DRUG: pretarsal injection of Botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bazedoxifene/Conjugated Estrogens (BZA/CE) Improvement of Metabolism (BIM)
Status: COMPLETED
Conditions: Obesity|Glucose Homeostasis|Postmenopausal Symptoms
Interventions: DRUG: Bazedoxifene/Conjugated Estrogens (BZA/CE)|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer
Status: COMPLETED
Conditions: Acute Undifferentiated Leukemia|Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative|Childhood Acute Lymphoblastic Leukemia|Childhood Acute Myeloid Leukemia|Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Childhood Solid Neoplasm|Chronic Lymphocytic Leukemia|Hairy Cell Leukemia|Juvenile Myelomonocytic Leukemia|Mast Cell Leukemia|Neoplasm of Uncertain Malignant Potential|Prolymphocytic Leukemia|Secondary Acute Myeloid Leukemia|T-Cell Large Granular Lymphocyte Leukemia
Interventions: OTHER: Cytology Specimen Collection Procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Possible Effects of Taking Mirabegron While Taking a Contraceptive Pill
Status: COMPLETED
Conditions: Healthy Volunteers|Pharmacokinetics of Mirabegron
Interventions: DRUG: Mirabegron|DRUG: Minidril|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Assessment of Pharmacokinetics, Efficacy, and Safety of 10% IVIg in Pediatric PID Patients (KIDCARES10)
Status: RECRUITING
Conditions: Primary Immunodeficiency Disease
Interventions: BIOLOGICAL: Kedrion IVIG 10%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of SAB-185 in Ambulatory Participants With COVID-19
Status: UNKNOWN
Conditions: COVID-19|SARS-CoV2
Interventions: BIOLOGICAL: SAB-185|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Preliminary Efficacy and Pharmacokinetics of 3810
Status: UNKNOWN
Conditions: Advanced Solid Tumor|Advanced/Metastatic Colorectal Cancer
Interventions: DRUG: AL3810|DRUG: AL3810|DRUG: AL3810
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety, Tolerability, Immunogenicity and Efficacy of a Novel Method in Specific Immunotherapy in Cat Allergic Patients: a Placebo Controlled Trial
Status: COMPLETED
Conditions: Allergy to Cat Dander
Interventions: DRUG: IVN201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Position and Angle Marking System (PAMS) for Ultrasound-guided Neuraxial Procedures
Status: UNKNOWN
Conditions: Ultrasound-guided Neuraxial Procedures
Interventions: DEVICE: Position and Angle Marking System|DEVICE: Standard clinical practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Two Different Surgical Techniques in Hip Resurfacing Arthroplasty
Status: COMPLETED
Conditions: Osteonecrosis|Femoral Neck Fracture|Implant Failure
Interventions: PROCEDURE: Surgical approach (ReCap Hip Resurfacing System)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Perforated Collagen Membrane With Nanohydroxyapatite for Intrabony Defects
Status: COMPLETED
Conditions: Intrabony Periodontal Defect
Interventions: PROCEDURE: Open flap debridment|OTHER: Perforated collagen membrane|OTHER: Occlusive membrane|OTHER: Nanohydroxyapetite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dipyridamole to Prevent Coronavirus Exacerbation of Respiratory Status (DICER) in COVID-19
Status: COMPLETED
Conditions: COVID|Corona Virus Infection|Covid-19|SARS-CoV-2 Infection
Interventions: DRUG: Dipyridamole 100 Milligram(mg)|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Prilocaine vs Bupivacaine on Hemodynamics in Spinal Anesthesia for Geriatric Patients
Status: RECRUITING
Conditions: Hemodynamic Instability
Interventions: DRUG: Prilocaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Accurate Screening and Prevention of Cervical Lesions-- Development of Accurate Screening Methods for Cervical Lesions
Status: RECRUITING
Conditions: Cervical Intraepithelial Neoplasia Grade 2/3|Cervical Lesion
Interventions: DIAGNOSTIC_TEST: TCT test|DIAGNOSTIC_TEST: Vaginoscopy|DIAGNOSTIC_TEST: High throughput HPV typing and integration detection methods|DIAGNOSTIC_TEST: Cobas HPV test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of a N95 Respirator vs Cloth Mask on Exercise Capacity During Treadmill Exercise.
Status: COMPLETED
Conditions: COVID-19
Interventions: DEVICE: N-95 Respirator|DEVICE: Cloth Face Mask|DIAGNOSTIC_TEST: Graded exercise test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of the Placebo Effect on the Effects of Trancranial Direct Current Stimulation in Fibromyalgia
Status: ACTIVE_NOT_RECRUITING
Conditions: Fibromyalgia
Interventions: DEVICE: s-Tdcs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transctunaous Pulsed Radiofrequency Therapy in Carpal Tunnel Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Neuropathy|Chronic Pain
Interventions: DEVICE: Wrist splint|OTHER: Pulsed radiofrequency current
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study for Black Men With Prostate Cancer: Optimization Of Mental and Heart Health, the BOOM-Heart Study
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Cognitive behavioral therapy (supportive counseling)|BEHAVIORAL: Virtual Cardiac Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Durvalumab and Lenvatinib With or Without Chemotherapy in First-Line Treatment of Advanced Biliary Tract Cancer
Status: RECRUITING
Conditions: Biliary Tract Neoplasms|Immunotherapy
Interventions: DRUG: Durvalumab|DRUG: Lenvatinib Oral Product|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endotracheal Tube Placement Using McGrath MAC® Video Laryngoscope Versus Macintosh Laryngoscope
Status: WITHDRAWN
Conditions: Intubation
Interventions: DEVICE: McGrath MAC® Video Laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Interferon-α for TP53 Myeloid Malignancy Post Allo-HSCT
Status: RECRUITING
Conditions: Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: IFN-Α
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postmortem Evaluation of Adrenal and Other Endocrine Tumors in Patients With Sudden Death
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Aldosteronism|Adrenal Cushing Syndrome|Pheochromocytoma|Endocrine Neoplasia
Interventions: DIAGNOSTIC_TEST: Adrenal aldosterone synthase (CYP11B2) staining|DIAGNOSTIC_TEST: Adrenal cortisol synthase (CYP11B1) staining|DIAGNOSTIC_TEST: Histopathological analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intervention of HIV, Drug Use and the Criminal Justice System in Malaysia
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|Acquired Immunodeficiency Syndrome|Opiate Addiction|Drug Dependence
Interventions: DRUG: Methadone|BEHAVIORAL: Holistic Health Recovery Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Bupropion / Varenicline for Smoking Cessation in Male Smokers
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: Chantix|DRUG: Zyban|DRUG: Nicotine patches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: End to End Versus Side to End Anastomosis After Anterior Resection of Cancer Rectum
Status: RECRUITING
Conditions: Rectum Cancer
Interventions: PROCEDURE: Anterior resection of Rectal cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of AZD4635 With Durvalumab and With Cabazitaxel and Durvalumab in Patients With mCRPC.
Status: COMPLETED
Conditions: Progressive Metastatic Castrate-Resistant Prostate Cancer
Interventions: DRUG: AZD4635|DRUG: Durvalumab|DRUG: Cabazitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Objective Assessment of Hemodynamics in Preterm Neonates
Status: TERMINATED
Conditions: Hypotension and Shock|Hypoperfusion|Hemodynamic Instability|Intraventricular Hemorrhage|Cardiac Function|Circulatory Transition
Interventions: DEVICE: Multimodal objective non-invasive Monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Relationship Between Cardiovascular Disease in Asthma and Eosinophil Subtypes and Biomarkers of Bronchial Remodeling.
Status: NOT_YET_RECRUITING
Conditions: Asthma|Cardiovascular Diseases
Interventions: OTHER: Asthma and cardiovascular disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Study of Techniques in Melanocyte-Keratinocyte Transplantation for the Treatment of Vitiligo
Status: WITHDRAWN
Conditions: Vitiligo
Interventions: PROCEDURE: Melanocyte Keratinocyte transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Isotonic Solutions and Major Adverse Renal Events Trial in the Non-Medical Intensive Care Unit (SMART-SURG)
Status: COMPLETED
Conditions: Critical Illness|Acute Kidney Injury
Interventions: OTHER: 0.9% Saline|OTHER: Physiologically-balanced isotonic crystalloid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Flossing Technique With Neuromuscular Reeducation Exercises in Trained Subjects
Status: COMPLETED
Conditions: Weight, Body
Interventions: OTHER: Flossing|OTHER: Reeducation exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of Titanium-Prepared Platelet-Rich Fibrin on Angiogenic Biomarkers in Gingival Crevicular Fluid
Status: COMPLETED
Conditions: Chronic Periodontitis|Intrabony Periodontal Defect
Interventions: PROCEDURE: T-PRF|PROCEDURE: Allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT