pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Investigate the Interaction of BMS-986322 and a Combined Oral Hormonal Contraceptive (Ethinyl Estradiol [EE]/Norethindrone [NET]) in Healthy Female Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986322|DRUG: Loestrin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiology Regarding Apnoeic Oxygenation During Nasal Cannula Therapy at Different Flow Rates
Status: COMPLETED
Conditions: Apnoeic Oxygenation
Interventions: DRUG: Oxygen 70l/min|DRUG: Oxygen 10 l/min|DRUG: Oxygen 2l/min|PROCEDURE: Jaw thrust|PROCEDURE: Videolaryngoscopy|DRUG: oxygen 0.25l/min
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Supplementation Trial of KOKO Plus Among HIV Exposed Children in Accra
Status: UNKNOWN
Conditions: HIV Infections|Nutrition Poor|Child Development
Interventions: DIETARY_SUPPLEMENT: KOKOPlus protein and micronutrient powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Enteral Zinc Supplementation in Very Low Birth Weight Infants
Status: NOT_YET_RECRUITING
Conditions: Very Low Birth Weight Infant|Nutritional Deficiency
Interventions: DRUG: Zinc Sulfate|OTHER: Sterile Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Strategies for Optimizing Brain Health And Managing Transgenerational Vascular Risk Factors Post-Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke, Ischemic
Interventions: BEHAVIORAL: CHAMPS-TR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessments of Sarcopenia Prevalence in Chronic Heart Failure Patients and in Subjects Before TAVI
Status: UNKNOWN
Conditions: Sarcopenia|Chronic Heart Failure
Interventions: DIAGNOSTIC_TEST: Assessment of sarcopenia prevalence
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tissue Penetration of Ceftolozane/Tazobactam in Diabetic Patients With Lower Limb Infections
Status: COMPLETED
Conditions: Diabetes|Wound Infection|Healthy Volunteers
Interventions: DRUG: Ceftolozane/tazobactam|PROCEDURE: Microdialysis Catheter Insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Hypothermia on Delayed Neurocognitive Recovery (DNR): an Observational Trial Among Patients Undergoing Cardiac-Surgery
Status: COMPLETED
Conditions: Cognitive Dysfunction|Emergence Delirium|Hypothermia
Interventions: PROCEDURE: Hypothermia during Extracorporeal Circulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy of Lacticum Acidum Homaccord in the Treatment of Chronic Tension-type Headaches
Status: COMPLETED
Conditions: Chronic Tension-type Headaches
Interventions: OTHER: Lacticum acidum homaccord|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The EVARREST® Pediatric Mild or Moderate Liver and Soft Tissue Bleeding Study
Status: RECRUITING
Conditions: Controlling Mild to Moderate Bleeding During Surgery
Interventions: BIOLOGICAL: EVARREST® Fibrin Sealant Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neutrophil CD64 and Procalcitonin as Novel Biomarkers for Postoperative Infections
Status: COMPLETED
Conditions: Bacterial Infection|Postoperative Infection|Abdominal Infection
Interventions: OTHER: CD64 and Procalcitonin|OTHER: CD64 and Procalcitonin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vitamin D3 Treatment in Pediatric Systemic Lupus Erythematosus
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Vitamin D3 6000 IU|DRUG: Vitamin D3 400 IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Clinical Trial of CPC/rhBMP-2 Microffolds as Bone Substitute for Bone Regeneration
Status: COMPLETED
Conditions: Bone Fracture
Interventions: PROCEDURE: Minimally invasive internal fixation surgeries|DEVICE: CPC/rhBMP-2 micro-scaffolds|DEVICE: CPC paste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TXA and Corona Virus 2019 (COVID19) in Outpatients
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: Tranexamic acid tablets|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Accelerated Phase Chronic Myelogenous Leukemia|Adult Acute Lymphoblastic Leukemia in Remission|Adult Acute Myeloid Leukemia in Remission|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Blastic Phase Chronic Myelogenous Leukemia|Childhood Acute Lymphoblastic Leukemia in Remission|Childhood Acute Myeloid Leukemia in Remission|Childhood Chronic Myelogenous Leukemia|Childhood Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia|de Novo Myelodysplastic Syndromes|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Secondary Myelodysplastic Syndromes|Untreated Adult Acute Lymphoblastic Leukemia|Untreated Childhood Acute Lymphoblastic Leukemia
Interventions: DRUG: treosulfan|DRUG: fludarabine phosphate|RADIATION: total-body irradiation|PROCEDURE: peripheral blood stem cell transplantation|DRUG: tacrolimus|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: allogeneic hematopoietic stem cell transplantation|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nefopam and Morphine Consumption in the Treatment of Ureteral Calculi
Status: COMPLETED
Conditions: Ureteral Calculi, Hyperalgic, Not Complicated
Interventions: DRUG: Néfopam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody Therapy in Treating Patients With Lymphoma or Leukemia
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: monoclonal antibody CD19|BIOLOGICAL: monoclonal antibody CD20|PROCEDURE: in vitro-treated peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Sintilimab With Pemigatinib in Patients With PD-L1-positive and FGFR Mutated Advanced Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Advanced Non Small Cell Lung Cancer
Interventions: DRUG: Sintilimab|DRUG: Pemigatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of the Safety and Efficacy of Two Probiotic Strains
Status: NOT_YET_RECRUITING
Conditions: Gastrointestinal Dysfunction
Interventions: DIETARY_SUPPLEMENT: Placebo 1 to Probiotic A|DIETARY_SUPPLEMENT: Probiotic A to Placebo 1|DIETARY_SUPPLEMENT: Placebo 2 to Probiotic B|DIETARY_SUPPLEMENT: Probiotic B to Placebo 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Regional Anesthesia for Cardiothoracic Enhanced Recovery (RACER) Study
Status: COMPLETED
Conditions: Congenital Heart Defect|Congenital Heart Disease|Anesthesia, Local|Opioid Use
Interventions: PROCEDURE: Bilateral Erector Spinae Plane Block (ESPB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Gevokizumab to Treat Moderate to Severe Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Placebo|DRUG: gevokizumab|DRUG: gevokizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GDT-PPV Protocol in Thoracic Surgery
Status: RECRUITING
Conditions: Thoracic Surgery|Fluid-therapy
Interventions: OTHER: PPV-GDT|OTHER: Zero-balance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stemchymal® for Polyglutamine Spinocerebellar Ataxia
Status: NOT_YET_RECRUITING
Conditions: Spinocerebellar Ataxias
Interventions: BIOLOGICAL: Stemchymal|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interactive Virtual Telerehabilitation After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Interactive Virtual Telerehabilitation (IVT)|OTHER: Standard care rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Characteristics in Advanced Renal Cell Carcinoma and Daily Practice Treatment With Nexavar
Status: COMPLETED
Conditions: Carcinoma, Renal Cell|Carcinoma, Renal Cell (Advanced)
Interventions: DRUG: Nexavar (Sorafenib, BAY43-9006)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ART Drug Dosage Adjustment in HIV-infected Population
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Tenofovir(TDF)+Lamivudine(3TC)+Efavirenz(EFV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Nasonex® in Improving Sleep Disturbances Related to Perennial Allergic Rhinitis (Study P04909)(TERMINATED)
Status: TERMINATED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: Mometasone Furoate Nasal Spray|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Safety and Tolerability of Dabigatran Etexilate Solution in Children 1 to < 2 Years of Age
Status: WITHDRAWN
Conditions: Venous Thromboembolism
Interventions: DRUG: dabigatran etexilate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Consistency & Immunogenicity Study of 3 Lots of GSK's Hib Conjugate Vaccine Versus ActHIB & Pentacel in Healthy Infants
Status: COMPLETED
Conditions: Haemophilus Influenzae Type b
Interventions: BIOLOGICAL: GSK Biologicals' Haemophilus influenzae type b vaccine (GSK 208108)|BIOLOGICAL: ActHIB™|BIOLOGICAL: Pentacel™|BIOLOGICAL: Pediarix™|BIOLOGICAL: Prevnar 13™|BIOLOGICAL: Rotarix™|BIOLOGICAL: Engerix™-B|BIOLOGICAL: Infanrix™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Gemcitabine and Bevacizumab in Treating Patients With Pancreatic Cancer That Has Been Completely Removed By Surgery
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: gemcitabine hydrochloride|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scrambler Therapy in the Treatment of Chronic Chemotherapy-Induced Peripheral Neuropathy
Status: COMPLETED
Conditions: Neuropathy
Interventions: DEVICE: Scrambler Therapy|DEVICE: Sham Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety of Fluvastatin-Celebrex Association in Low-grade and High Grade Optico-chiasmatic Gliomas
Status: COMPLETED
Conditions: Glioma
Interventions: DRUG: Fluvastatine|DRUG: Celebrex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of 2 Weeks Treatment With Dapagliflozin in Subjects With an Impaired Glucose Homeostasis on Nocturnal Substrate Oxidation
Status: COMPLETED
Conditions: Prediabetic State|Substrate Oxidation
Interventions: DRUG: Dapagliflozin 10mg|DRUG: Placebo matching to Dapagliflozin 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Does an Active Range of Motion Monitor Improve Outcomes/Decrease Cost for Patients Undergoing Total Knee Arthroplasty?
Status: UNKNOWN
Conditions: Total Knee Arthroplasty (TKA)
Interventions: DEVICE: Knee Glider
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of the Compound Extracted From Azadirachta Indica Leaves in the Treatment of Arsenical Keratosis
Status: UNKNOWN
Conditions: Keratotic Nodular Size
Interventions: DRUG: Azadirachta indica leaves extract containing ointment intervention.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of GLYC-101 to Evaluate Outcomes After Post-laser Ablation
Status: COMPLETED
Conditions: Wounds
Interventions: DRUG: Placebo gel|DRUG: GLYC-101 gel (1.0 %)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PR104 in Treating Patients With Previously Untreated or Relapsed Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: PR104|OTHER: F-18-fluoromisonidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: DRUG: Arginine|DRUG: Arginine (Loading)|DRUG: Arginine (Continuous)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Pneumatic Compression in Surgical Patients at Extremely-high Risk for Venous Thromboembolism
Status: COMPLETED
Conditions: Venous Thromboembolism|Venous Thrombosis
Interventions: DEVICE: SCD|DEVICE: GCS|DRUG: LMWH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of REC-4881 in Participants With Cancers Which Have an AXIN1 or APC Mutation
Status: RECRUITING
Conditions: AXIN1 Gene Mutation|APC Gene Mutation|Solid Tumor
Interventions: DRUG: REC-4881
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of VR Versus CT in Sensorimotor Function of Upper Extremity in Chronic Stroke Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Stroke
Interventions: COMBINATION_PRODUCT: Virtual Reality (VR) Therapy|DIAGNOSTIC_TEST: Conservative Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TDF and LdT in Immune-tolerant CHB Patients Awaiting Assisted Reproduction
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Tenofovir and telbivudine|DRUG: Tenofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of an Anti-Allergy Drug With a Contact Lens in the Treatment of Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Ketotifen with a Contact Lens (no generic name)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: To Study the Effects of Lipid Emulsion on Hemodynamics in Organophosphate Compound Poisoning
Status: COMPLETED
Conditions: Organophosphate Poisoning
Interventions: COMBINATION_PRODUCT: Lipid Emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bowel Preparation Before Hemorrhoidectomy
Status: ENROLLING_BY_INVITATION
Conditions: HEMORRHOIDECTOMY
Interventions: DRUG: Group that will undergo bowel preparation using laxatives (Two bowel X-M Solution 250 ml.)|DRUG: Group that will undergo bowel preparation using enema (Two bowel E.S. Enema )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Online Group Therapy Interventions for Procrastination
Status: ACTIVE_NOT_RECRUITING
Conditions: Procrastination
Interventions: BEHAVIORAL: Psychoeducation and cognitive modules|BEHAVIORAL: Behavioral module: Starting on Time and Planning Realistically|BEHAVIORAL: Behavioral module: Working Time Restriction|BEHAVIORAL: Behavioral module: Pomodoro Time Management Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Adolescent Fibromyalgia Study
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: placebo|DRUG: pregabalin (Lyrica)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vinorelbine, Cisplatin, Disulfiram and Copper in CTC_EMT Positive Refractory Metastatic Breast Cancer.
Status: WITHDRAWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Disulfiram|DRUG: Vinorelbin|DRUG: Cisplatin|DRUG: Copper
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Repaglinide, Glurenorm® and Glucobay® in Chinese Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: repaglinide|DRUG: Glurenorm®|DRUG: Glucobay®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Listening to Music and Stress Ball Application on Patients' Anxiety Level and Hemodynamic Parameters During PCI
Status: COMPLETED
Conditions: Percutaneous Coronary Intervention|Anxiety|Hemodynamics
Interventions: OTHER: Music|OTHER: Stress ball
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Recombinant Human Interleukin-11 (I) (Baijieyi) for Prevention and Treatment of Chemotherapy-induced Thrombocytopenia in Patients With Malignant Tumor
Status: UNKNOWN
Conditions: Chemotherapy-induced Thrombocytopenia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ibrutinib, Idarubicin and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Recurrent Adult Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|DRUG: Ibrutinib|DRUG: Idarubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simple Technique to Improve Diagnostic Yield in EUS-FNA
Status: COMPLETED
Conditions: Lesion Sampled for Cytology
Interventions: OTHER: Twisted Syringe|OTHER: Conventional Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study to Compare the Pharmacokinetic Characteristics of CKD-395 0.25/500mg in Healthy Male Volunteers
Status: COMPLETED
Conditions: Diabetes Mellitus, Type II
Interventions: DRUG: Duvie Tab. 0.5mg, Glucophage XR Tab. 500mg|DRUG: CKD-395 0.25/500mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Treatment of Inflammation Before Stem Cell Transplant in People With a Primary Immune Regulatory Disorder (PIRD) and/or an Autoinflammatory Condition
Status: RECRUITING
Conditions: Primary Immune Regulatory Disorder|Autoimmune Lymphoproliferative|Immune System Diseases
Interventions: DRUG: Emapalumab|DRUG: Fludarabine and Dexamethasone|PROCEDURE: Stem Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Efficacy of 14-day Triple Therapy: Clarithromycin vs. Levofloxacin on Eradication of H. Pylori
Status: UNKNOWN
Conditions: Helicobacter Pylori Gastrointestinal Tract Infection
Interventions: DRUG: Clarithromycin|DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of Nu.Q™ Biomarkers to Help Guiding the Management of Osteoarticular Infections
Status: COMPLETED
Conditions: Diabetic Foot|Chronic Osteomyelitis|Septic Arthritis
Interventions: DIAGNOSTIC_TEST: Histones H3.1 blood levels
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Gender-Specific Posterior Cruciate-Substituting High-Flexion Knee Prosthesis Does Not Improve Fit and Function
Status: COMPLETED
Conditions: Osteoarthritis of the Knee|Female
Interventions: DEVICE: Standard LPS flex TKA|DEVICE: Gender specific LPS -Flex TKA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Cognitive Remediation in Patients With Schizophrenia or Schizoaffective Disorder Stabilized on Lurasidone
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Cognitive Remediation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of BIBR 953 ZW After BIBR 1048 (Oral Pro-drug of BIBR 953 ZW) Administered as Hydroxypropyl Methylcellulose (HPMC) Polymorph II Capsule Relative to HPMC Polymorph I Capsule in Healthy Subjects.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBR 1048 MS polymorph II|DRUG: BIBR 1048 MS polymorph I
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olaparib in Unresectable/Metastatic Melanoma With BRCA1/2
Status: WITHDRAWN
Conditions: Recurrent Metastatic Melanoma|Cutaneous Melanoma|Mucosal Melanoma|Uveal Melanoma
Interventions: DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Ketamine Intrathecal and iv Dexamethasone for Post Cesarean Analgesia
Status: NOT_YET_RECRUITING
Conditions: Post Cesarean Analgesia
Interventions: DRUG: Ketamine|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Paramedic - Norwegian Acute Stroke Prehospital Project
Status: UNKNOWN
Conditions: Stroke|Triage|Paramedic|Mobile Application
Interventions: DIAGNOSTIC_TEST: eSTROKE model|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MICHI™ Neuroprotection System (NPS+f) Filter Debris Analysis Study (The F-1 Study)
Status: COMPLETED
Conditions: Internal Carotid Artery Stenosis
Interventions: DEVICE: MICHI(TM) NPS+f|PROCEDURE: transcarotid stenting
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The (Cost-)Effectiveness of Nurse Practitioners Working at the Primary Out of Hours Emergency Service
Status: COMPLETED
Conditions: Out of Hours Medical Care|Primary Health Care
Interventions: OTHER: Other, care provided by Nurse Practitioners
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Adjuvant Chemotherapy of Three-step Regimen in BRCA1/2 Wide Type Ovarian Cancer (ACTS-2)
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Etoposide, Cyclophosphamide, Carboplatin/Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Ixazomib in Combination With Lenalidomide and Dexamethasone in Patients With Relapsed and/or Refractory Multiple Myeloma Initially Treated With an Injection of Proteasome Inhibitor-Based Therapy
Status: COMPLETED
Conditions: Relapsed and/or Refractory Multiple Myeloma
Interventions: DRUG: Ixazomib|DRUG: Bortezomib|DRUG: Carfilzomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Hygiene Regimen in Patients on HCT
Status: UNKNOWN
Conditions: Oral Mucositis
Interventions: DRUG: .02% Chlorohexidine Gluconate|DRUG: 3% Sodium Bicarbonate|DRUG: Nystatin 10000U/ml|DEVICE: Extra Soft Toothbrush|DRUG: Supersaturated Calcium Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Video-Feedback Interaction Guidance for Improving Interactions Between Depressed Mothers and Their Infants ("VID-KIDS")
Status: ACTIVE_NOT_RECRUITING
Conditions: Post Partum Depression
Interventions: BEHAVIORAL: VID-KIDS Intervention Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Berberine on Preventing Cardiovascular Disease and Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: PreDiabetes|Abdominal Obesity|Hypertension|Dyslipidemias
Interventions: DRUG: Berberine plus lifestyle intervention|BEHAVIORAL: Placebo plus lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self-proning and Repositioning in COVID-19 Outpatients at Risk of Complicated Illness
Status: TERMINATED
Conditions: COVID-19|COVID-19 Pneumonia|Proning|Hospitalization|Death|Outpatient|Complication
Interventions: OTHER: Self-proning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apricity CARE to Improve ICI Outcomes of Ethnic/Racial Minority NSCLC Patients
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: OTHER: Apricity C.A.R.E. Program for Cancer Adverse events Rapid Evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Safety and How the Body Affects a Drug (CNTO 1959) in Healthy Volunteers and in Patients With Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: CNTO 1959; Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Improving the Management of Obesity in Primary Care Practice (The Power-UP Trial)
Status: COMPLETED
Conditions: Obesity|Hypercholesterolemia|Metabolic Syndrome|Hypertension|Diabetes
Interventions: BEHAVIORAL: Usual Care|BEHAVIORAL: Brief Lifestyle Counseling|BEHAVIORAL: Enhanced Brief Lifestyle Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation and Acute Respiratory Infection in Older Long-Term Care Residents
Status: COMPLETED
Conditions: Respiratory Infection
Interventions: DRUG: High Dose Vitamin D|DRUG: Standard Dose Vitamin D|DRUG: Placebo|DIETARY_SUPPLEMENT: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sugar Text: A Randomized Controlled Trial of a Text Message Intervention for Women With Diabetes in Pregnancy
Status: COMPLETED
Conditions: Diabetes in Pregnancy|Gestational Diabetes|Texting Interventions
Interventions: BEHAVIORAL: Text Message Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Motor Learning for Upper Limb Hemiparesis After Stroke
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke|Hemiparesis
Interventions: BEHAVIORAL: Practice Variable|BEHAVIORAL: No Practice Variable
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparisons Between Isoperistaltic and Antiperistaltic Gastrojejunostomy in Laparoscopic Distal Gastrectomy
Status: UNKNOWN
Conditions: Stomach Neoplasms
Interventions: PROCEDURE: Isoperistaltic|PROCEDURE: Antiperistaltic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Decolonization of Methicillin-resistant Staphylococcus Aureus (MRSA) Using Theraworx
Status: WITHDRAWN
Conditions: Methicillin-Resistant Staphylococcus Aureus
Interventions: OTHER: Theraworx|DRUG: mupirocin antibiotic ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Bempedoic Acid on Liver Fat in Individuals With Nonalcoholic Fatty Liver Disease and Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes|Non Alcholic Fatty Liver Disease
Interventions: DRUG: Bempedoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Immunogenicity and Safety of the Vaccine Against Influenza A/H1N1
Status: WITHDRAWN
Conditions: Influenza
Interventions: BIOLOGICAL: Vaccine Sanofi A(H1N1) 15 ug & trivalent|BIOLOGICAL: Vaccine Sanofi (H1N1) 15 ug.nonadyuvante|BIOLOGICAL: Vaccine Sanofi A(H1N1) 7.5 ug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bictegravir/FTC/TAF for the Treatment of Primary HIV Infection
Status: UNKNOWN
Conditions: HIV Primary Infection
Interventions: DRUG: 50mg bictegravir/200mg emtricitabine/25mg tenofovir alafenamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Efficacy and Safety of Non-Invasive RF Treatment in Refractory MGD
Status: RECRUITING
Conditions: Dry Eye Syndromes|Meibomian Gland Dysfunction
Interventions: DEVICE: The Thermage FLX System|DEVICE: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: APAP Hepatotoxicity After Therapeutic Doses
Status: UNKNOWN
Conditions: Paracetamol Toxicity|Hepatotoxicity|Malnutrition
Interventions: DIAGNOSTIC_TEST: Hepatic function monitoring|DIAGNOSTIC_TEST: Nutritional status assesment|OTHER: Biomarker research sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improvement of Live Babies Rates After ICSI, Using cpFT
Status: RECRUITING
Conditions: Infertility|Oocyte|Pregnancy
Interventions: DRUG: Cyclic peptide Fertiline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physiologic Ocular Changes During Pregnancy in Women With High Myopia.
Status: NOT_YET_RECRUITING
Conditions: High Myopia|Pregnancy Related
Interventions: DEVICE: Corneal topography, Optical coherence tomography (OCT) and Optical coherence tomography angiography (OCTA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Test of the Efficacy and Safety of Insulin Glulisine Injected Subcutaneously in Patients With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: INSULIN GLULISINE (HMR1964)|DRUG: INSULIN GLARGINE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes
Status: RECRUITING
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Bimatoprost Ophthalmic Solution, 0.01%|DRUG: LUMIGAN® (bimatoprost ophthalmic solution) 0.01%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of a New Formula in Infants With Cow's Milk Protein Allergy
Status: COMPLETED
Conditions: Milk Hypersensitivity|Food Sensitivity|Protein Allergy
Interventions: DIETARY_SUPPLEMENT: extensively hydrolyzed rice protein formula
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: Rituximab and Combination Chemotherapy in Treating Patients With Previously Untreated High- or High-Intermediate-Risk Diffuse Large B-Cell Lymphoma
Status: WITHDRAWN
Conditions: Contiguous Stage II Adult Diffuse Large Cell Lymphoma|Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma|Stage I Adult Diffuse Large Cell Lymphoma|Stage III Adult Diffuse Large Cell Lymphoma|Stage IV Adult Diffuse Large Cell Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: vincristine sulfate|DRUG: prednisone|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bromelain and Escin in the Reduction of Postoperative Sequelae in Periodontal and Implant Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Edema|Swelling Lips & Face
Interventions: OTHER: Bromelains and Escin Oral Tablet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acceptance-based Healthy Lifestyles Program for Patients With Pneumoconiosis
Status: NOT_YET_RECRUITING
Conditions: Pneumoconiosis|Healthy Lifestyle
Interventions: OTHER: Acceptance-based healthy lifestyles program (intervention group)|OTHER: Acceptance-based healthy lifestyles program (control group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Lessening Organ Dysfunction With VITamin C
Status: COMPLETED
Conditions: Sepsis|Vitamin C|Intensive Care Unit|COVID-19|Pandemic|Coronavirus
Interventions: DRUG: Vitamin C|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cabazitaxel in Combination With 177Lu-PSMA-617 in Metastatic Castration-resistant Prostate Cancer
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer|mCRPC
Interventions: DRUG: Cabazitaxel|DRUG: 177Lu-PSMA-617
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Tacrolimus for Breast Cancer-related Lymphedema
Status: NOT_YET_RECRUITING
Conditions: Lymphedema
Interventions: DRUG: Tacrolimus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Benefit of Enhanced Contact Endoscopy in Pre-histological Diagnosis of Laryngeal and Hypopharyngeal Mucosal Lesions
Status: RECRUITING
Conditions: Laryngeal Disease|Laryngeal Lesions|Hypopharyngeal Lesions|Suspected Laryngeal Cancer|Suspected Hypopharyngeal Cancer|Proven Laryngeal Cancer|Proven Hypopharyngeal Cancer
Interventions: DIAGNOSTIC_TEST: Enhanced contact endoscopy|DIAGNOSTIC_TEST: Narrow band imaging|DIAGNOSTIC_TEST: IMAGE1S imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Molecular Marker Profiling of Axillary Lymph Nodes in Predicting Response in Patients With Locally Advanced or Metastatic Breast Cancer Who Are Undergoing Chemotherapy Followed By Surgery
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: PET (positron emission tomography)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leidos-Enabled Adaptive Protocol for Clinical Trials (LEAP-CT) in Hospitalized Patients With COVID-19 (Addendum 1)
Status: WITHDRAWN
Conditions: 2019 Novel Coronavirus Disease|2019 Novel Coronavirus Infection|2019-nCoV Disease|2019-nCoV Infection|COVID-19 Pandemic|COVID-19 Virus Disease|COVID-19 Virus Infection|Covid19|Coronavirus Disease 2019|SARS-CoV-2 Infection|SARS-CoV-2 Acute Respiratory Disease|COVID-19
Interventions: DRUG: Famotidine|DRUG: Celecoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Diet and Exercise
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: Cagrilintide|DRUG: Semaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Chest-wall and Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Definity Suspension for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of Tiotropium and Salmeterol After Inhalation of a Fixed Combined Dose Compared to Monocomponents in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tiotropium/Salmeterol|DRUG: Serevent® Diskus®|DRUG: Spiriva®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical SB-275833 Ointment, 1% For The Treatment Of Impetigo
Status: COMPLETED
Conditions: Skin Infections, Bacterial
Interventions: DRUG: SB-275833 ointment, 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Menaquinone-7
Status: COMPLETED
Conditions: Bioavailability
Interventions: DIETARY_SUPPLEMENT: MK-7 containing capsule|DIETARY_SUPPLEMENT: basic yogurt enriched with MK-7|DIETARY_SUPPLEMENT: nutrient-enriched yogurt with MK-7
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Upadacitinib (ABT-494) to Placebo in Participants With Active Psoriatic Arthritis Who Have a History of Inadequate Response to at Least One Biologic Disease Modifying Anti-Rheumatic Drug (bDMARD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Psoriatic Arthritis
Interventions: DRUG: Upadacitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dysphagia Following Anterior Cervical Spine Surgery; Single Dose Steroid vs Saline (DysDexVSSal)
Status: ACTIVE_NOT_RECRUITING
Conditions: Dysphagia
Interventions: DRUG: Dexamethasone|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial Comparing the Safety and Efficacy of Semaglutide Once Weekly in Monotherapy or in Combination With One OAD in Japanese Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: semaglutide|DRUG: DPP-4 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Venous and Arterial Thromboembolism, in Cancer Patients Undergoing Chemotherapy, With a Low Molecular Weight Heparin (Nadroparin Calcium)
Status: COMPLETED
Conditions: Advanced Cancer|Metastatic Cancer
Interventions: DRUG: Nadroparin calcium|DRUG: saline solution (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Contrast Enhanced Spectral Mammography (CESM) for Women With Palpable Breast Abnormalities
Status: COMPLETED
Conditions: Breast Abnormalities
Interventions: OTHER: Contrast Enhanced Spectral Mammography (CESM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety & Tolerability Study of Chimeric Antigen Receptor T-Reg Cell Therapy in Living Donor Renal Transplant Recipients
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Transplant Rejection|End Stage Renal Disease
Interventions: BIOLOGICAL: TX200-TR101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Postoperative Pain After Activation of Irrigant
Status: RECRUITING
Conditions: Pain
Interventions: DEVICE: Conventional root canal treatment|DEVICE: Ultrasonic|DEVICE: Apical negative pressure|DEVICE: Combined Ultrasonic and negative pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Comparing Artesunate Tablet To Arsuamoon® Tablets (Guilin-China) In Healthy Subjects
Status: COMPLETED
Conditions: Falciparum Malaria
Interventions: DRUG: Artesunate (Test)|DRUG: Artesunate (Comparator)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Glycemic and Insulinemic Response of Durum Wheat Bread
Status: COMPLETED
Conditions: Glucose Response|Glycemic Index|Insulin Response|Oral Processing
Interventions: OTHER: consumption of glucose solution 1|OTHER: consumption of glucose solution 2|OTHER: consumption of Bread A and oral processing|OTHER: consumption of Bread B and oral processing|OTHER: consumption of Bread C and oral processing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Locally Invasive NSCLC Treated With NEo-Adjuvant Stereotactic Body RadioTherapy and REsection
Status: UNKNOWN
Conditions: Non-Small-Cell Lung Cancer|Carcinoma
Interventions: RADIATION: Neoadjuvant Stereotactic body radiation (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation to Treat Recurrent C. Difficile Associated Diarrhea Via Retention Enema or Oral Route
Status: COMPLETED
Conditions: C. Difficile
Interventions: BIOLOGICAL: Frozen Microbiota|BIOLOGICAL: Lyophilized Microbiota
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A European Study on Medical Management Versus TAG Device + Medical Management for Acute Uncomplicated Type B Dissection
Status: COMPLETED
Conditions: Aortic Diseases
Interventions: DEVICE: Gore TAG Endoprosthesis|OTHER: Best Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT