pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Randomized Study of the Efficacy and Safety of a Single Dose of Synvisc-One® in Chinese Patients With Symptomatic Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Hylan G-F 20 (GZ402662/SAR402662)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Health and Wellbeing for People Diagnosed With Chronic Spontaneous Urticaria (CSU)
Status: SUSPENDED
Conditions: Chronic Spontaneous Urticaria
Interventions: OTHER: ABT Online Programme|OTHER: Delayed Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: World Maternal Antifibrinolytic Trial
Status: COMPLETED
Conditions: Postpartum Haemorrhage
Interventions: DRUG: Tranexamic acid|DRUG: Placebo [Saline]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy Study of the Monoclonal Antibody, CT-011, in Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma|Malignant Melanoma
Interventions: DRUG: CT-011
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REgulatory T Cell Therapy to Achieve Immunosuppression REduction
Status: NOT_YET_RECRUITING
Conditions: Kidney Transplantation
Interventions: DRUG: Arm 1: SOC (mTOR + CNI)|BIOLOGICAL: Arm 2A: TRACT/MONO mTOR|BIOLOGICAL: Arm 2B: TRACT/MONO CNI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK117 as Monotherapy or in Combination With AK104
Status: COMPLETED
Conditions: Neoplasms Malignant
Interventions: DRUG: AK117|DRUG: AK117+AK104
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abdominal and Lower Extremity Compression During Tilt Table Testing in Adolescent POTS Patients
Status: COMPLETED
Conditions: Postural Orthostatic Tachycardia Syndrome (POTS)|Syncope
Interventions: DEVICE: Zoex compression garment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Root Canal Shaping With TruNatomy on Postoperative Pain and Operative Torque Generated During Instrumentation
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: PROCEDURE: Root canal treatment using TruNaomy rotary files|PROCEDURE: Root canal treatment using race rotary instruments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
Status: RECRUITING
Conditions: Metastatic Solid Tumor|Recurrent Solid Tumor|Advanced Solid Tumor|Urinary Bladder Neoplasm|Triple Negative Breast Cancer|Non-small Cell Lung Cancer|Esophageal Cancer|Pancreatic Cancer|Ovarian Cancer|Cervical Cancer|Head and Neck Squamous Cell Carcinoma|Prostate Cancer|Renal Pelvis Cancer|Bladder Cancer
Interventions: DRUG: LY4052031
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CSD190101: A Study to Assess Nicotine Pharmacokinetic Parameters After Use of Two Smokeless Tobacco Products
Status: COMPLETED
Conditions: Tobacco Use
Interventions: OTHER: A19010-F|OTHER: B19010-F
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Atomoxetine Treatment for ADHD and Marijuana Dependence
Status: COMPLETED
Conditions: Marijuana Abuse|Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Atomoxetine|PROCEDURE: Motivational enhancement therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study for Use of Dutasteride (Avodart) With Testosterone Replacement
Status: COMPLETED
Conditions: Hypogonadism
Interventions: DRUG: dutasteride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nerve-sparing, Robot-assisted Radical Prostatectomy Using a Personalized, 3D-printed Prostate Model for Selective Resection of Positive Surgical Margins
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: 3D model guided secondary resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of CBP-174 in Healthy Adults
Status: COMPLETED
Conditions: Healthy Adult Subjects
Interventions: DRUG: CBP-174|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Trial of Alerting to Extended Hypotensive Exposures on Long-Term Outcome After Surgery
Status: WITHDRAWN
Conditions: Anesthesia|Hypotension
Interventions: BEHAVIORAL: Electronic alert to SLUScore increase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Prosthetic Management of All on Four Versus All on Six to Rehabilitate Completely Edentulous Maxillary Ridge Opposed by Natural Teeth
Status: ACTIVE_NOT_RECRUITING
Conditions: Prosthesis Survival
Interventions: PROCEDURE: implant supported maxillary fixed prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Low Doses of Cholestyramine in the Treatment of Hyperthyroidism
Status: COMPLETED
Conditions: Graves Disease
Interventions: DRUG: Cholestyramine|DRUG: Cholestyramine|DRUG: Placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Patient and Family Health Using Family-Centered Outcomes and Shared Decision-Making
Status: RECRUITING
Conditions: Patient Decision Aids|Congenital Heart Disease|Congenital Heart Defect
Interventions: OTHER: Decision Aid|OTHER: Values Clarification Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Safety and Immunogenicity of a Human Papillomavirus (HPV) Vaccine in Human Immunodeficiency Virus (HIV) Infected Females
Status: COMPLETED
Conditions: Infections, Papillomavirus|Papillomavirus Vaccines
Interventions: BIOLOGICAL: GSK Biologicals' HPV vaccine 580299|BIOLOGICAL: Merck's Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine (Gardasil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pectoralis Minor Release Versus Non-release in RSA
Status: NOT_YET_RECRUITING
Conditions: Reverse Total Shoulder Arthroplasty|Rotator Cuff Tear Arthropathy|Advanced Glenohumeral Osteoarthritis
Interventions: PROCEDURE: Pectoralis Minor Release|PROCEDURE: RSA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Residential Treatment Gains for Adolescents
Status: RECRUITING
Conditions: Parenting|Adolescent - Emotional Problem|Mental Disorder in Adolescence
Interventions: BEHAVIORAL: Parenting Wisely Residential Treatment (PWRT)|BEHAVIORAL: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Enhanced Consent and Preparedness for Surgery Trial
Status: COMPLETED
Conditions: Stress Urinary Incontinence|Urge Incontinence|Pelvic Organ Prolapse
Interventions: OTHER: audiovisual decision aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of Cobicistat-boosted Darunavir in HIV Infected Adults
Status: COMPLETED
Conditions: Acquired Immunodeficiency Syndrome|HIV Infections
Interventions: DRUG: COBI|DRUG: DRV|DRUG: NRTIs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chitosan Nerv Tube for Primary Repair of Traumatic Sensory Nerve Lesions of the Hand
Status: UNKNOWN
Conditions: Traumatic Lesion of Sensory Nerves of the Hand
Interventions: DEVICE: Chitosan nerve tube in addition to gold standard therapy|PROCEDURE: Gold standard Primary microsurgical repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Eltrombopag In Patients With Severe and Very Severe Aplastic Anemia
Status: COMPLETED
Conditions: Severe Aplastic Anemia|Very Severe Aplastic Anemia|Moderate Aplastic Anemia
Interventions: DRUG: Eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Ferric Carboxymaltose on Hemoglobin Response and Transfusion in Patients With Iron Deficiency Anemia After Off-Pump Coronary Artery Bypass Grafting
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Ferinject|DRUG: Normal Saline Flush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pompe & Pain - Study to Assess Nociceptive Pain in Adult Patients With Pompe Disease
Status: RECRUITING
Conditions: Pompe Disease (Late-onset)|Inclusion Body Myositis|Spinal Muscular Atrophy Type 3|FSHD
Interventions: DIAGNOSTIC_TEST: Beck depression inventory fast screen (Questionnaire)|DIAGNOSTIC_TEST: Brief Pain Inventory (BPI) (Questionnaire)|DIAGNOSTIC_TEST: German Pain Inventory (Questionnaire)|DIAGNOSTIC_TEST: Fatigue Severity and Disability Scale (FSS) (Questionnaire)|DIAGNOSTIC_TEST: Rotterdam Handicap Scale (RHS) (Questionnaire)|DIAGNOSTIC_TEST: R-PAct (Questionnaire)|DIAGNOSTIC_TEST: Quick Motor Function Test|DIAGNOSTIC_TEST: Handheld Dynamometry (HHD)|DIAGNOSTIC_TEST: Six-minute walk test (6MWT)|DIAGNOSTIC_TEST: Pressure pain threshold|DIAGNOSTIC_TEST: Muscle ultrasound|DIAGNOSTIC_TEST: Vital signs|DIAGNOSTIC_TEST: Borg Scale|DIAGNOSTIC_TEST: Laboratory assessment: Creatine kinase|DIAGNOSTIC_TEST: Laboratory assessment: Vitamin D Level|DIAGNOSTIC_TEST: Laboratory assessment: calcium|DIAGNOSTIC_TEST: Laboratory assessment: magnesium|DIAGNOSTIC_TEST: Laboratory assessment: phosphate|GENETIC: Genetic test: ACE polymorphism|GENETIC: Genetic test: ACTN3 polymorphism|GENETIC: Blood draw for optional genetic exome sequencing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SGLT2 Inhibitors and Reducing the Risk of Cancers Among Diabetics , an Observational Study
Status: ENROLLING_BY_INVITATION
Conditions: Cancer|Diabetes Mellitus, Type 2|Interleukin 6|SGLT2 Inhibitors
Interventions: DIAGNOSTIC_TEST: interleukin 6
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CDP-choline Treatment in ATS Users
Status: UNKNOWN
Conditions: Substance Use Disorders
Interventions: DRUG: CDP-choline|DRUG: Placebo|BEHAVIORAL: Supportive psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study to Evaluate the Effect of Two Different Doses of Enoxaparin Sodium in Combination With Standard Chemotherapy in Patients With Stage Small Cell Lung Cancer (SCLC)
Status: WITHDRAWN
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Etoposide|DRUG: Cisplatin|DRUG: enoxaparin sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label, Extension Study of PRO044 in Duchenne Muscular Dystrophy (DMD)
Status: TERMINATED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: PRO044 SC 6 mg/kg|DRUG: PRO044 IV 6 mg/kg|DRUG: PRO044 IV 9 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Culturally Tailored Educational and Support Program to Increase Quality of Life Among Korean Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Linguistically and Culturally Tailored Information|BEHAVIORAL: Cognitive-Behavioral Stress Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Performance of Toric Hydrogel Contact Lenses Following One Week of Daily Wear
Status: COMPLETED
Conditions: Astigmatism
Interventions: DEVICE: filcon IV1 toric lens|DEVICE: ocufilcon D toric lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Light Therapy for Treatment of Overuse Anterior Knee Pain
Status: COMPLETED
Conditions: Anterior Knee Pain Syndrome
Interventions: DEVICE: THOR Laser LX2 System|DEVICE: Sham Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Sleep Strip OTC™ Accuracy in Screening for Sleep Apnea Syndrome Against the Reference Method, an In-lab Full Night Polysomnographic (PSG)
Status: COMPLETED
Conditions: Sleep Apnea Syndrome
Interventions: DEVICE: SleepStrip OTC(TM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Phyllanthus Niruri and Sida Cordifolia in Diabetic Peripheral Polyneuropathy
Status: COMPLETED
Conditions: Diabetic Polyneuropathy|Diabetic Neuralgia|Diabetic Neuropathies|Diabetic Neuropathy
Interventions: DRUG: Sida cordifolia roots|DRUG: Phyllanthus niruri|DRUG: Sida cordifolia roots extract|DRUG: Phyllanthus niruri extract|OTHER: Sida cordifolia placebo|OTHER: Phyllanthus niruri placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gefitinib With or Without Chemotherapy in Brain Metastases From Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer|Brain Metastases|EGFR Mutation
Interventions: DRUG: Gefitinib and Pemetrexed/platinum|DRUG: Gefitinib mono-therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Towards Life-Long Healthy Lungs: A Multidisciplinary Follow-up Framework for Preterm Infants
Status: RECRUITING
Conditions: Premature Birth|Respiratory Disease|Respiratory Tract Infections|Preterm Birth|Bronchopulmonary Dysplasia|Pollution Related Respiratory Disorder|Pollution; Exposure|Smoking Cessation|Health-Related Behavior|RSV Infection|RSV Pneumonia|Bronchial Hyperreactivity|Telemedicine|eHealth
Interventions: COMBINATION_PRODUCT: LONG LOVE Framework
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Need for Compression Bandage Following Total Knee Arthroplasty A Prospective Randomized Controlled Trial Conducted in Simultaneous Bilateral Total Knee Replacements
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: DEVICE: Compression bandage|DEVICE: Gauze dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CPX-351 in Treating Patients With Relapsed or Refractory High Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia
Status: RECRUITING
Conditions: Blasts 10-19 Percent of Bone Marrow Nucleated Cells|Blasts More Than 5 Percent of Bone Marrow Nucleated Cells|High Risk Chronic Myelomonocytic Leukemia|Recurrent Chronic Myelomonocytic Leukemia|Recurrent High Risk Myelodysplastic Syndrome|Refractory Chronic Myelomonocytic Leukemia|Refractory High Risk Myelodysplastic Syndrome
Interventions: DRUG: Liposome-encapsulated Daunorubicin-Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Using Reduced Fluence Parameters in Photocoagulation for Diabetic Retinopathy.
Status: TERMINATED
Conditions: Proliferative Diabetic Retinopathy
Interventions: PROCEDURE: Retinal laser photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Green Tea on Level of Serum Uric Acid in Healthy Individuals
Status: COMPLETED
Conditions: Hyperuricemia|Gout
Interventions: DIETARY_SUPPLEMENT: green tea extracts 2 gm/day|DIETARY_SUPPLEMENT: green tea extracts 4 gm/day|DIETARY_SUPPLEMENT: green tea extracts 6 gm/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Comparison of DDT2 Contact Lens and a Daily Disposable Contact Lens - Study 1
Status: COMPLETED
Conditions: Refractive Error|Myopia
Interventions: DEVICE: Verofilcon A contact lenses|DEVICE: Etafilcon A contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Propafenone Versus Amiodarone in Septic Shock
Status: COMPLETED
Conditions: Supraventricular Arrhythmia|Septic Shock
Interventions: DRUG: Propafenone i.v.|DRUG: Amiodarone i.v.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Virtual Reality on the Quality of Life of Oncology Patients
Status: RECRUITING
Conditions: Cancer
Interventions: OTHER: Measure the improvement in quality of life|OTHER: Measure the level of satisfaction of patients and nursing staff|OTHER: Measurement of anxiety and pain|OTHER: Measurement of depressive state|OTHER: measuring fatigue levels|OTHER: measurement of acute nausea and vomiting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of DMF (Dimethyl Fumarate) and Its Impact on PROs (Patient Reported Outcomes) in Treatment-Naive or Suboptimal IFN (Interferon) or GA (Glatiramer Acetate) Responders With RRMS (ImPROve)
Status: TERMINATED
Conditions: Multiple Sclerosis, Relapsing-Remitting|Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: dimethyl fumarate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Effectiveness Study for Surgery vs. Non-Surgery in Patients With Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: open or endoscopic discectomy|PROCEDURE: epidural block|OTHER: exercise|DRUG: ibuprofen, naxoprofen, Cox-2 inhibitor, aceclofenac|PROCEDURE: decompression|PROCEDURE: instrumentation and fusion|DRUG: codeine, oxycontine, IRcodone, Tramadol|PROCEDURE: epidural adhesiolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ocular Coherence Tomography During Cataract Assessment
Status: COMPLETED
Conditions: Cataract Senile|Macula Hole|Epiretinal Membrane|Age Related Macular Degeneration|Vitreomacular Traction
Interventions: DIAGNOSTIC_TEST: Ocular Coherence Tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multidisciplinary and Coordinated Follow-up Based on a Telemonitoring Web Platform for Improving CPAP Compliance in Low Cardiovascular Risk Sleep Apnea Patients : OPTISAS 1 Study
Status: UNKNOWN
Conditions: Sleep Apnea Syndrome|Low Cardiovascular Risk
Interventions: DEVICE: Continuous Positive Airway Pressure (CPAP) in sleep apnea patients|DEVICE: Continuous Positive Airway Pressure (CPAP) in sleep apnea patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RECOVER-VITAL: Platform Protocol to Measure the Effects of Antiviral Therapies on Long COVID Symptoms
Status: RECRUITING
Conditions: Long COVID|Long Covid19
Interventions: DRUG: Experimental: Paxlovid 25 day dosing|DRUG: Experimental: Paxlovid 15 day dosing|DRUG: Placebo Comparator: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety and Efficacy of an OC Preparation vs Placebo for 6 Treatment Cycles in Women With Moderate Acne.
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: YAZ (DRSP 3 mg/EE 0.02 mg, BAY86-5300)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AEG35156 in Combination With High-dose Cytarabine and Idarubicin in AML Following Failure of a Single Standard Dose Cytarabine Based Frontline Induction Regimen
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: AEG35156
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Methods of Vaginal Cuff Closure at Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Total Laparoscopic Hysterectomy|Benign Conditions
Interventions: PROCEDURE: Cuff closure via vaginal route|PROCEDURE: Cuff closure via laparoscopic route
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Drug-drug Interaction Potential of BMS-986196 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BMS-986196|DRUG: Caffeine|DRUG: Montelukast|DRUG: Flurbiprofen|DRUG: Omeprazole|DRUG: Midazolam|DRUG: Digoxin|DRUG: Pravastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetics Study to Investigate the Effect of Vemurafenib on Digoxin in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma, Neoplasms
Interventions: DRUG: Digoxin|DRUG: Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Radiation Safety Climate in the Hybrid Angiography Suite
Status: COMPLETED
Conditions: Healthy Volunteers|Aortic Aneurysm, Abdominal
Interventions: OTHER: Assessment of radiation safety climate|OTHER: Assessment of radiation safety behavior|OTHER: Assessment of radiation safety knowledge and motivation|OTHER: Data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Immunogenicity of ChulaCov19 BNA159 mRNA Vaccine
Status: RECRUITING
Conditions: Safety of 25 ug of ChulaCov19-BNA159 mRNA Vaccine|Tolerability of 25 ug of ChulaCov19-BNA159 mRNA Vaccine|Immune Response of 25 ug of ChulaCov19-BNA159 mRNA Vaccine|Safety of 50 ug of ChulaCov19-BNA159 mRNA Vaccine|Tolerability of 50 ug of ChulaCov19-BNA159 mRNA Vaccine|Immune Response of 50 ug of ChulaCov19-BNA159 mRNA Vaccine|Assess Which Dose is Appropriate to Use
Interventions: BIOLOGICAL: ChulaCov19 BNA159 mRNA vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fully Covered SEMS Versus Partially Covered SEMS With Anti-migration System for Malignant Distal Biliary Obstruction
Status: UNKNOWN
Conditions: Biliary Tract Neoplasms
Interventions: DEVICE: partially covered SEMS|DEVICE: fully covered SEMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin and Pembrolizumab in Treating Patients With Recurrent Peripheral T-Cell Lymphoma
Status: WITHDRAWN
Conditions: Recurrent Angioimmunoblastic T-Cell Lymphoma|Recurrent Enteropathy-Associated T-Cell Lymphoma|Recurrent Follicular T-Cell Lymphoma|Recurrent Hepatosplenic T-Cell Lymphoma|Recurrent Nodal Peripheral T-Cell Lymphoma With TFH Phenotype|Recurrent Peripheral T-Cell Lymphoma, Not Otherwise Specified|Recurrent Subcutaneous Panniculitis-Like T-Cell Lymphoma|Refractory Angioimmunoblastic T-Cell Lymphoma|Refractory Enteropathy-Associated T-Cell Lymphoma|Refractory Follicular T-Cell Lymphoma|Refractory Hepatosplenic T-Cell Lymphoma|Refractory Nodal Peripheral T-Cell Lymphoma With TFH Phenotype|Refractory Peripheral T-Cell Lymphoma, Not Otherwise Specified|Refractory Subcutaneous Panniculitis-Like T-Cell Lymphoma
Interventions: DRUG: Brentuximab Vedotin|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Depth of Anesthesia as Measured by Bispectral Index (BIS) on Emergence Agitation in Children
Status: COMPLETED
Conditions: Emergence Agitation
Interventions: OTHER: Depth of anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Sorafenib, Cetuximab, and Irinotecan in Treating Patients With Advanced or Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage III Colon Cancer|Stage III Rectal Cancer|Stage IV Colon Cancer|Stage IV Rectal Cancer
Interventions: DRUG: sorafenib tosylate|DRUG: cetuximab|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GSM (Genitourinary Syndrome Of Menopause) Management In Breast Cancer Survivors
Status: TERMINATED
Conditions: Genitourinary Abnormality|Breast Cancer Female|Vaginal Abnormality|Urinary Tract Infections|Dyspareunia|Dysuria
Interventions: COMBINATION_PRODUCT: Replens and coconut oil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Home-Based Ankle Training Program on The Muscle Strength, Balance and Gait Function in the Elderly
Status: COMPLETED
Conditions: Aging
Interventions: BEHAVIORAL: Resistance training (New ankle machine training)|BEHAVIORAL: Resistance training (Elastic band training )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Find Out Whether BI 1015550 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF)
Status: ACTIVE_NOT_RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: BI 1015550|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Augmentation of the Antidepressant Action of Sertraline With Triiodothyronine (T3)and Reboxetine: Clinical Efficacy, Adverse Effects and Predictors of Response.
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: sertraline|DRUG: triiodothyronine (T3)|DRUG: reboxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation and Comparison of a Novel Dentrifice Formulation on Plaque Removal
Status: COMPLETED
Conditions: Dental Plaque
Interventions: DRUG: Protegera™ toothpaste (NaF)|DRUG: Crest™ Cavity Protection toothpaste (NaF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Internet-delivered CBT for Irritable Bowel Syndrome in Adolescents
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Functional Gastrointestinal Disorders
Interventions: BEHAVIORAL: Internetdelivered exposure-based CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain in the Surgical Treatment of Hemorrhoids: Conventional Hemorrhoidectomy With a Monopolar Electric Scaler VS Bipolar Energy With Caiman® (Aesculap®)
Status: RECRUITING
Conditions: Hemorrhoid Pain|Hemorrhoidectomy
Interventions: PROCEDURE: Monopolar Hemorroidecotmy|PROCEDURE: Caiman Hemorroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capsaicin to Prevent Delayed Chemotherapy Induced Nausea and Vomiting (CapCIN)
Status: COMPLETED
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Capsaicin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Alanyl-glutamine Supplementation for C. Difficile Treatment (ACT)
Status: RECRUITING
Conditions: Clostridioides Difficile Infection|Clostridium Difficile Infection|Clostridium Difficile Diarrhea|Clostridia Difficile Colitis
Interventions: DRUG: Alanyl-glutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Magnesium Supplementation in COPD
Status: UNKNOWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DIETARY_SUPPLEMENT: 300 mg of citrate Mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spot-Check Noninvasive Hemoglobin (SpHb) Clinical Validation of INVSENSOR00026
Status: COMPLETED
Conditions: Anemia
Interventions: DEVICE: INVSENSOR00026 (Pulse CO-Oximeter and sensor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cardiac Risk Assessment Using Standard of Care Versus CTA and Heart Flow FFRct
Status: WITHDRAWN
Conditions: Coronary Artery Disease|Acute Liver Failure|Liver Transplant
Interventions: DIAGNOSTIC_TEST: CTA/FFRct|DIAGNOSTIC_TEST: SOC cardiovascular evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Oral ORIN1001 in Subjects With Idiopathic Pulmonary Fibrosis (IPF)
Status: ACTIVE_NOT_RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: ORIN1001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: the Study of Effect of Chronomodulated Chemotherapy on the Dendritic Cells Subsets in the Treatment of Advanced Nasopharyngeal Cancer
Status: UNKNOWN
Conditions: Locally Advanced Head and Neck Squamous Cell Carcinoma
Interventions: DEVICE: Chrono-chemotherapy|DEVICE: Routine intravenous drip|DRUG: induction Chrono-chemotherapy|DRUG: induction Routine-chemotherapy|DRUG: cisplatin chrono-chemotherapy|DRUG: cisplatin routine-chemotherapy|RADIATION: intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Web-Based Training for Covid-19 Patients on Symptom Management, Medication Compliance and Quality of Life
Status: UNKNOWN
Conditions: COVID-19
Interventions: OTHER: intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing the Effectiveness Between Ritonavir Boosted Atazanavir and Efavirenz for the First HIV Treatment
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: atazanavir arm|DRUG: efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Inflammation and Oxidative Stress in Persons Undergoing Dialysis
Status: COMPLETED
Conditions: End Stage Renal Failure on Dialysis|Complication of Hemodialysis
Interventions: DRUG: Placebo|DRUG: Ramipril|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimisation of Antibiotic Prescription in Acute Noncomplicated Respiratory Tract Infections in Children (OptimAP Study)
Status: COMPLETED
Conditions: Acute Respiratory Tract Infections
Interventions: BEHAVIORAL: Communication skills training|BEHAVIORAL: Mobile phone application on RTI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of Physical Exercise at the Workplace (IRMA09) - Laboratory Technicians
Status: COMPLETED
Conditions: Musculoskeletal Disorders|Stress
Interventions: BEHAVIORAL: Biopsychosocial|BEHAVIORAL: Reference
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrative Coping Group for Children
Status: COMPLETED
Conditions: Childhood Depression|Childhood Anxiety|Pediatric Pain|Migraines|ADHD|Pediatric Stomach Pain|Musculoskeletal Pain
Interventions: BEHAVIORAL: Integrative Coping Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reproducibility of Glucose Fluctuations by Standardized Exercise for Patients With Type 1 Diabetes - a Method Study Based on Continuous Glucose Monitoring
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Exercise|Continuous Glucose Monitoring
Interventions: BEHAVIORAL: Blood glucose measured using CGM during standardized physical activity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Effect of Food and Posture on the Pharmacokinetics of a Single Dose of ER OROS Paliperidone
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Extended release OROS paliperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiplex Strip Polymerase Chain Reaction for Diagnosis of Eye Infection Diseases From Corneal Scraping Samples
Status: UNKNOWN
Conditions: Endophthalmitis|Keratitis|Corneal Ulcer|Eye Infections
Interventions: DIAGNOSTIC_TEST: Multiplex Strip PCR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reducing Risk for Alzheimer's Disease in High-Risk Women Through Yogic Meditation Training
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Alzheimer's Disease
Interventions: BEHAVIORAL: Memory Training|BEHAVIORAL: Kundalini yoga and meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Doxorubicin and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) and Intraoperative Brachytherapy for Unresectable or Refractory Pelvic and Abdominal Rhabdomyosarcoma and Undifferentiated Sarcomas in Children
Status: WITHDRAWN
Conditions: Malignant Neoplasms of Mesothelial and Soft Tissue|Rhabdomyosarcoma, Pelvic|Rhabdomyosarcoma, Abdominal
Interventions: PROCEDURE: Abdominal Surgery|DRUG: Doxorubicin|RADIATION: Intra-Operative Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Coreg CR and Lisinopril on Markers for Cardiovascular Functional and Structural Disease
Status: COMPLETED
Conditions: Pre-hypertension
Interventions: DRUG: carvedilol phosphate|DRUG: lisinopril|DRUG: carvedilol phosphate and lisinopril|DRUG: placebo and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NUMITOR Study: Nummular Headache Iberian Study on the Treatments and Outcomes in Real-World Setting
Status: RECRUITING
Conditions: Headache Disorders, Secondary|Headache Disorders|Central Nervous System Diseases|Brain Diseases|Neurologic Manifestations|Nervous System Diseases|Pain
Interventions: DRUG: Clinical evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact of Different Carbohydrate Restriction After a Gastric Bypass on the Ketosis and Ketoacidosis
Status: RECRUITING
Conditions: Obesity, Morbid|NASH|Ketosis|Keto Acidosis|Carbohydrate Metabolism Disorder
Interventions: OTHER: Carbohydrate Restriction after a Gastric Bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endotrol-tracheal Tube Assisted Endotracheal Intubation During Video Laryngoscopy
Status: COMPLETED
Conditions: Endotracheal Intubation
Interventions: DEVICE: Glidescope videolaryngoscope|DEVICE: McGrath videolaryngoscope|DEVICE: Non-styletted Endotrol endotracheal tube (ETT)|DEVICE: Regular endotracheal tube (ETT) with Gliderite stylet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of IQP-VV-102 in Weight Management
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DIETARY_SUPPLEMENT: IQP-VV-102|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: Cagrilintide|DRUG: Semaglutide|DRUG: Tirzepatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Postpartum Depression Be Prevented With Care
Status: COMPLETED
Conditions: Sleep Quality, Depression, Postnatal Care, Single-Blind Method, Fatigue, Social Support
Interventions: BEHAVIORAL: A nursing care program was applied for the intervention group under the guidance of Levine's conservation model.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound-guided Percutaneous Electrolysis Compared to Placebo Acupuncture in Posterolateral Lumbar Disc Herniation
Status: COMPLETED
Conditions: Posterolateral Disc Herniation L4-L5-S1|Disk Herniated Lumbar
Interventions: OTHER: US guided PE|OTHER: Sham Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-durg Interaction of SHR3680 With Digoxin, Rosuvastatin Calcium and Metformin Hydrochloride
Status: UNKNOWN
Conditions: Drug-drug Interaction,SHR3680
Interventions: DRUG: SHR3680|DRUG: digoxin|DRUG: Rosuvastatin calcium|DRUG: metformin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine, Capecitabine, Oxaliplatin, and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Sunitinib Malate for Metastatic and/or Surgically Unresectable Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Liposarcoma|Leiomyosarcoma|Fibrosarcoma|Malignant Fibrous Histiocytoma
Interventions: DRUG: Sunitinib Malate (SU011248)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the SMART Stent in the Treatment SFA Disease.
Status: COMPLETED
Conditions: Peripheral Artery Disease
Interventions: DEVICE: drug-eluting stent|DEVICE: bare-metal stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Creatine and Ubiquinol for Sperm Quality
Status: RECRUITING
Conditions: Oligospermia|Sperm Count, Low
Interventions: DIETARY_SUPPLEMENT: Supplement 1|DIETARY_SUPPLEMENT: Supplement 2|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Program of Health Behaviour Against to Cancer (PHeBAC)
Status: RECRUITING
Conditions: Cancer Prevention|Health Behavior|Disability, Intellectual|Parents|Cancer Screening|Experimental Study Designs|Mothers|Disabilities Mental
Interventions: BEHAVIORAL: PHeBAC|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lipid Lowering in Patients With Statin Intolerance
Status: COMPLETED
Conditions: Hyperlipidemia|Coronary Artery Disease
Interventions: DRUG: red yeast rice|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Left Atrial Function Changes After Left Atrial Appendage Closure in Patients With Persistent Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Left atrial appendage closure|PROCEDURE: Radiofrequency ablation|PROCEDURE: LAAC combined with radiofrequency ablation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Function in Patients Treated for Metastatic Melanoma With Immune Checkpoint Inhibitors
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma|Cognitive Impairment|Fatigue|Sleep|Depression, Anxiety|Quality of Life|Inflammation|Sickness Behavior|Cancer-related Cognitive Impairment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neoadjuvant Run-In Study With TAK-228 Followed by Letrozole/TAK-228 in Women With High-Risk ER+/HER2- Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: TAK-228|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnosis by Comprehensive Cardiovascular Imaging for Stroke and TIA
Status: UNKNOWN
Conditions: Stroke|Transient Ischaemic Attack
Interventions: DIAGNOSTIC_TEST: CCI scanning (CTA, cardiac CT), and MRI scanning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Application of Anterior Quadratus Lumborum Block at the Lateral Supra-arcuate Ligament Under Laparoscopic Direct Vision in Laparoscopic Renal Surgery
Status: RECRUITING
Conditions: Postoperative Pain|Analgesia|Quadratus Lumborum Block|Laparoscopic Renal Surgery
Interventions: PROCEDURE: Anterior Quadratus Lumborum Block at the lateral supra-arcuate ligament under laparoscopic direct vision|PROCEDURE: Local infiltration anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microwave Ablation in Mild Axillary Hidradenitis Suppurativa
Status: TERMINATED
Conditions: Hidradenitis Suppurativa|Acne Inversa
Interventions: DEVICE: Microwave ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunologic Response to FluMist vs. Flucelvax
Status: COMPLETED
Conditions: Influenza, Human|Immune Response
Interventions: BIOLOGICAL: FluMist live attenuated influenza vaccine|BIOLOGICAL: Flucelvax inactivated influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of the Rapid Intravascular Start (RIVS) System Versus Conventional Catheter
Status: TERMINATED
Conditions: Vascular Access Complication
Interventions: DEVICE: RIVS vascular access|DEVICE: Conventional vascular access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: EGD vs EUS in Diagnosing Portal Hypertension in Cirrhotic Patients.
Status: UNKNOWN
Conditions: Liver Cirrhoses|Portal Hypertension
Interventions: DIAGNOSTIC_TEST: Esophagogastroduodenoscopy|DIAGNOSTIC_TEST: Endoscopic ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC