pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Varlitinib in Combination With mFOLFOX6 for Advanced or Metastatic Gastric Cancer (First Line)
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Varlitinib|DRUG: mFOLFOX6|DRUG: Placebo|DRUG: mFOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Electrical Stimulation in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: neuromuscular electrical stimulation (NMES)|OTHER: Sham electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare IBI305 and Bevacizumab on Pharmacokinetics/Safety/Immunogenicity on Healthy Male
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: IBI305(Bevacizumab Biosimilar)|DRUG: Avastin(Bevacizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Balloon Pulmonary Angioplasty in Non-operable CTEPH Patients
Status: UNKNOWN
Conditions: Chronic Thromboembolic Pulmonary Hypertension
Interventions: PROCEDURE: Balloon Pulmonary Angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Activation and Medication Optimization for Perioperative Mental Health Feasibility Study
Status: COMPLETED
Conditions: Older Adults|Anxiety|Depression|Cardiac Surgery|Orthopedic Surgery|Major Surgical Resection of a Thoracic Malignancy|Major Surgical Resection of an Abdominal Malignancy
Interventions: BEHAVIORAL: Behavioral Activation|OTHER: Medication Optimization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine as an Additive to Local Anaesthesia to Decrease Intraocular Pressure in Glaucoma Surgery
Status: UNKNOWN
Conditions: Glaucoma
Interventions: DRUG: Dexmedetomidine to reduce the IOP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Trial Protocol for the Inactivated Poliomyelitis Vaccine Made From Sabin Strains
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: Inactivated Poliomyelitis Vaccine (Sabin strains)|BIOLOGICAL: Inactivated Poliomyelitis Vaccine (Sabin strains)|BIOLOGICAL: Inactivated Poliomyelitis Vaccine (Sabin strains)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Text Message Quit Vaping Intervention for Adolescents
Status: COMPLETED
Conditions: Vaping|Cessation, Tobacco
Interventions: BEHAVIORAL: This is Quitting|OTHER: Assessment only control|OTHER: Waitlist control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Dapagliflozin to Reduce Burden of Atrial Fibrillation in Patients Undergoing Catheter Ablation of Symptomatic Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bicalutamide and Goserelin in Treating Patients With Cancer of the Ovary, Fallopian Tube, or Peritoneum
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: bicalutamide|DRUG: goserelin acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of ARQ 197 Versus Investigator's Choice of Second-Line Chemotherapy in Patients With Locally Advanced or Metastatic Gastric Cancer Who Have Progressive Neoplastic Disease Following Treatment With One Prior Chemotherapy Regimen
Status: WITHDRAWN
Conditions: Gastric Cancer
Interventions: DRUG: ARQ 197|DRUG: Oxaliplatin, capecitabine or irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With Cancer
Status: COMPLETED
Conditions: Adult Solid Tumor|Adenocarcinoma of the Colon|Adenocarcinoma of the Rectum|Adult Central Nervous System Germ Cell Tumor|Adult Teratoma|Benign Teratoma|Estrogen Receptor-negative Breast Cancer|Estrogen Receptor-positive Breast Cancer|Familial Testicular Germ Cell Tumor|HER2-negative Breast Cancer|HER2-positive Breast Cancer|Male Breast Cancer|Ovarian Immature Teratoma|Ovarian Mature Teratoma|Ovarian Monodermal and Highly Specialized Teratoma|Progesterone Receptor-negative Breast Cancer|Progesterone Receptor-positive Breast Cancer|Recurrent Breast Cancer|Recurrent Colon Cancer|Recurrent Extragonadal Germ Cell Tumor|Recurrent Extragonadal Non-seminomatous Germ Cell Tumor|Recurrent Extragonadal Seminoma|Recurrent Malignant Testicular Germ Cell Tumor|Recurrent Melanoma|Recurrent Ovarian Germ Cell Tumor|Recurrent Rectal Cancer|Stage III Extragonadal Non-seminomatous Germ Cell Tumor|Stage III Extragonadal Seminoma|Stage III Malignant Testicular Germ Cell Tumor|Stage III Ovarian Germ Cell Tumor|Stage IV Breast Cancer|Stage IV Colon Cancer|Stage IV Extragonadal Non-seminomatous Germ Cell Tumor|Stage IV Extragonadal Seminoma|Stage IV Melanoma|Stage IV Ovarian Germ Cell Tumor|Stage IV Rectal Cancer|Testicular Immature Teratoma|Testicular Mature Teratoma
Interventions: DRUG: PD-0332991
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Vitamin D Supplementation in Older Persons
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: cholecalciferol (vitamin D)|DIETARY_SUPPLEMENT: cholecalciferol (vitamin D)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Cocoa Flavanols on Insulin Resistance in an 'At-risk' Population
Status: COMPLETED
Conditions: Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: High Flavanol Cocoa|DIETARY_SUPPLEMENT: Low Flavanol Cocoa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: SGM-101 Tumor Targeted Fluorescence Endoscopy in Rectal Polyps With Suspected T1 Adenocarcinoma or High Grade Dysplasia
Status: RECRUITING
Conditions: Colorectal Cancer|Image|Low Grade Dysplasia of Colon
Interventions: DRUG: SGM-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Savolitinib Plus Durvalumab Versus Sunitinib and Durvalumab Monotherapy in MET-Driven, Unresectable and Locally Advanced or Metastatic PRCC
Status: RECRUITING
Conditions: Papillary Renal Cell Carcinoma
Interventions: DRUG: savolitinib|DRUG: durvalumab|DRUG: sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thalidomide in Treating Patients With Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Chronic Myelomonocytic Leukemia|de Novo Myelodysplastic Syndromes|Previously Treated Myelodysplastic Syndromes|Refractory Anemia|Refractory Anemia With Excess Blasts|Refractory Anemia With Excess Blasts in Transformation|Refractory Anemia With Ringed Sideroblasts|Secondary Myelodysplastic Syndromes
Interventions: DRUG: thalidomide|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Dexmedetomidine in ICU Patients Requiring Continuous Sedation
Status: COMPLETED
Conditions: Mechanically Ventilated and Intubated Subjects
Interventions: DRUG: Dexmedetomidine HCL Injection|DRUG: Midazolam Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Boceprevir in Pediatric Subjects With Chronic Hepatitis C Genotype 1 (P07614)
Status: TERMINATED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Boceprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motexafin Gadolinium and Radiation Therapy in Treating Young Patients With Pontine Glioma
Status: COMPLETED
Conditions: Untreated Childhood Brain Stem Glioma
Interventions: DRUG: motexafin gadolinium|RADIATION: 3-dimensional conformal radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coronary Artery Calcium-guided Primary Prevention of Major Coronary Heart Disease in Asymptomatic Diabetes
Status: ENROLLING_BY_INVITATION
Conditions: Type2 Diabetes|Coronary Heart Disease
Interventions: DIAGNOSTIC_TEST: Multi-Detector Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Empirical Comparative Study of Variation Blood Level Antibody Vitamin D at Scleroderma (SSc) Patients Compared Healthy Peoples
Status: UNKNOWN
Conditions: Scleroderma
Interventions: OTHER: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessing Knowledge of Dietary Sodium Content and Implementation of Color-Coded Cue Cards and Dietary Sodium
Status: COMPLETED
Conditions: Diet, Sodium-Restricted|Heart Failure C14.280.434
Interventions: BEHAVIORAL: Standard Dietary Sodium Education|BEHAVIORAL: Color-Coded Cue Cards
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Feasibility of a RCT That Compares Immediate Versus Optional Delayed Surgical Repair After ACL Injury
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Injuries
Interventions: PROCEDURE: Immediate anterior cruciate ligament reconstruction|OTHER: Rehabilitation|PROCEDURE: Optional delayed anterior cruciate ligament reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self-help Application for Eating Disorder
Status: RECRUITING
Conditions: Eating Disorder in Adolescents and Young Adults
Interventions: PROCEDURE: Arm I (Prepectoral),|PROCEDURE: Arm II (Subpectoral)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skills and Motivation at the Rhode Island Training School (Project SMART) - 1
Status: COMPLETED
Conditions: Alcoholic, Marijuana Misuse
Interventions: BEHAVIORAL: MI/CBT|BEHAVIORAL: RT/TU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Therapy for High-risk Hepatocellular Carcinoma Post Liver Transplantation
Status: NOT_YET_RECRUITING
Conditions: Liver Transplant; Complications|Hepatocarcinoma|Recurrent Osteosarcoma|High-Risk Cancer
Interventions: DRUG: multi-kinase inhibitors in combination with bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety Study of MELK Inhibitor to Treat Patients With Advanced Breast Cancer and Triple Negative Breast Cancer
Status: RECRUITING
Conditions: Relapsed/Refractory Locally Advanced or Metastatic Breast Cancer and Triple Negative Breast Cancer
Interventions: DRUG: OTS167PO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Installation of Non-invasive Ventilation at Home Using Telemedicine : a Pilot Study on Feasibility and Impact on Ventilation Compliance
Status: UNKNOWN
Conditions: Neuromuscular Diseases|Kyphoscoliosis|Non Invasive Ventilation
Interventions: DEVICE: Home NIV installation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of Iron and Folic Acid in New Test Supplement
Status: COMPLETED
Conditions: Iron Deficiency|Folic Acid Deficiency
Interventions: DIETARY_SUPPLEMENT: Daminaide 995 - SuppleFem Sprinkles|DIETARY_SUPPLEMENT: Materna
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Phase 2 Study of E6011 in Subjects With Rheumatoid Arthritis Inadequately Responding to Biologics
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: E6011|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SS1P and Pentostatin Plus Cyclophosphamide for Mesothelioma
Status: COMPLETED
Conditions: Mesothelioma|Adenocarcinoma of Lung|Pancreatic Neoplasms
Interventions: DRUG: Pentostatin|DRUG: Cyclophosphamide|BIOLOGICAL: SS1(dsFv)PE38 - lot 073I0809|BIOLOGICAL: SS1(dsFv)PE38 - lot FIL129J01
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of IgPro20 in Adults With Dermatomyositis (DM)
Status: ACTIVE_NOT_RECRUITING
Conditions: Dermatomyositis
Interventions: DRUG: human immunoglobulin G|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine on Tourniquet Induced -Systemic Effects
Status: COMPLETED
Conditions: Arthropathy of Knee|Spinal Anesthesia|Tourniquet|Ischemia-reperfusion Injury
Interventions: DRUG: Dexmedetomidine Hydrochloride, or Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Doxycycline Monohydrate 25 mg (5mL) Oral Suspension Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Doxycycline Monohydrate|DRUG: Doxycycline Monohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Coronary Access After Supra-Annular THV Implantation
Status: RECRUITING
Conditions: Coronary Angiography|Transcatheter Aortic Valve Replacement
Interventions: DIAGNOSTIC_TEST: Coronary Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Image Quality Between "Double Low Dose" Liver CT and Standard Liver CT
Status: RECRUITING
Conditions: Metastasis to Liver|Colorectal Cancer
Interventions: DIAGNOSTIC_TEST: Double low dose CT|DIAGNOSTIC_TEST: Standard dose CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Long-Term Efficacy and Safety of Ramelteon in Adults With Chronic Insomnia.
Status: COMPLETED
Conditions: Chronic Insomnia
Interventions: DRUG: Ramelteon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Radiation and Combination Chemotherapy Following Surgery in Children With Newly Diagnosed Medulloblastoma
Status: TERMINATED
Conditions: Brain Tumors|Central Nervous System Tumors|Medulloblastoma
Interventions: DRUG: Cisplatin|DRUG: Cyclophosphamide|DRUG: Etoposide|DRUG: Lomustine|DRUG: Vincristine|RADIATION: Craniospinal Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Sub Study to Evaluate the Study Medication (Etrasimod) Using Wearable Sensors in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Etrasimod Immediate Release (IR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing the Effects of Sertindole and Olanzapine on Cognition (SEROLA)
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Sertindole|DRUG: Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Optimal Treatment Duration of Bevacizumab Combination With Standard Chemotherapy in Patients With Ovarian Cancer
Status: COMPLETED
Conditions: Genital Diseases, Female|Ovarian Diseases|Ovarian Neoplasms|Fallopian Tube Neoplasms|Peritoneal Neoplasms
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Paclitaxel|DRUG: Carboplatin|OTHER: specialized pathology review (Germany only)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Safety and Efficacy of 3 Dosing Regimens of ABP-700 for Procedural Sedation in Adult Participants Undergoing Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: ABP-700
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Two Operational Techniques for Total Knee Replacement
Status: COMPLETED
Conditions: Gait, Unsteady|Knee Arthropathy|Surgery
Interventions: DIAGNOSTIC_TEST: REHAGAIT ANYLIZER
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Desensitizing Agent,Propolis After an In-office Vital Tooth Bleaching.
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: Propolis|DRUG: hydrogen peroxide 35%|OTHER: fluoride varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Cholesterol Lowering Effects of Strawberry
Status: COMPLETED
Conditions: Hypercholesterolemia|Glycemic Response
Interventions: DIETARY_SUPPLEMENT: Active Treatment Beverage|DIETARY_SUPPLEMENT: Placebo Treatment Beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Direct Angioplasty for Non ST Elevation Acute Coronary Events: DANCE Pilot Study
Status: TERMINATED
Conditions: Acute Coronary Syndrome
Interventions: PROCEDURE: Immediate Invasive Management|PROCEDURE: Conventional Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Supra-Pectineal QLS Plating Vs Infra-pectineal Plating in Management of Quadrilateral Plate Fractures
Status: ACTIVE_NOT_RECRUITING
Conditions: Evaluation of QL Buttress Plating in QLP Fracture Fixation
Interventions: PROCEDURE: suprapectineal quadrilateral buttress plating|PROCEDURE: Infra-pectineal plating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Should Preoperative Information Before Impacted Third Molar Extraction?
Status: COMPLETED
Conditions: Impacted Third Molar Tooth|Dental Anxiety
Interventions: BEHAVIORAL: Spielberger State Anxiety Inventory (STAI-S)|BEHAVIORAL: Dental Fear Scale (DFS)|BEHAVIORAL: Modified Dental Anxiety Scale (MDAS)|BEHAVIORAL: Visual Analog Scale (VAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interdisciplinary Rehabilitation for Chronic Pain in Primary Healthcare
Status: RECRUITING
Conditions: Chronic Pain|Pain Management
Interventions: OTHER: Interdisciplinary care + booster session (intervention)|OTHER: Interdisciplinary care (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Enteral Nutritional Supplementation on Patients With Oral and Oropharyngeal Cancer Undergoing Radio(Chemo)Therapy After Surgical
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: Early nutritional intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clopidogrel for the Prevention of Exacerbations in Severe COPD
Status: RECRUITING
Conditions: COPD|COPD Exacerbation Acute
Interventions: DRUG: Clopidogrel Bisulfate 75Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Olaparib in Recurrent/Metastatic, Platinum Resistant Nasopharyngeal Cancer
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Basiliximab, Cyclosporine/Cyclosporine Microemulsion, and Steroids in Pediatric de Novo Liver Transplant Recipients Avoiding Intraoperative Steroids
Status: COMPLETED
Conditions: Liver Transplantation|Infection
Interventions: DRUG: Basiliximab|DRUG: Cyclosporine/cyclosporine microemulsion|DRUG: Steroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Investigational Immuno-therapy Study of BMS-986205 Given in Combination With Nivolumab and in Combination With Both Nivolumab and Ipilimumab in Cancers That Are Advanced or Have Spread
Status: COMPLETED
Conditions: Advanced Cancer|Melanoma|Non-Small Cell Lung Cancer
Interventions: DRUG: BMS-986205|DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Innocell Autologous Cellular Immunotherapy in Recurrent Epithelial Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Ovarian Cancer
Interventions: BIOLOGICAL: Innocell Autologous Cellular Immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-arm Clinical Trial of IMGN853 in Chinese Adult Patients With Platinum-resistant, Epithelial Ovarian Cancer
Status: RECRUITING
Conditions: Epithelial Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Cancer
Interventions: DRUG: Mirvetuximab Soravtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of LentinexHP® on Quality of Life in Stage IV Colorectal Cancer
Status: RECRUITING
Conditions: Change in Mood|Change in Personality
Interventions: DIETARY_SUPPLEMENT: Undenatured beta-glucan solution|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Hyperbaric Oxygen in Patients With Perianal Crohn's Disease Already Treated With TNF Alpha Blockers Treated With TNF Alpha Blockers
Status: COMPLETED
Conditions: Crohn's Disease|Perianal Fistulas
Interventions: OTHER: Hyperbaric oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Light Timing Study
Status: RECRUITING
Conditions: Chronobiology|Light|Sleep|Circadian Rhythm|Adolescence
Interventions: BEHAVIORAL: Baseline Sleep Satiation and Phase Stabilization|BEHAVIORAL: Gradually Shifted Sleep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Efficacy and Safety of PB-201 in Type 2 Diabetic Mellitus Patients With Poor Glycemic Control Via Metformin Hydrochloride Monotherapy
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: PB-201|DRUG: PB-201 matched placebo|DRUG: Metformin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alternating Treatment With Fruquintinib and Bevacizumab Plus Capecitabine as Maintenance Therapy After First-Line Treatment in Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Fruquintinib alternating with Bevacizumab plus Capecitabine|DRUG: Bevacizumab plus Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Trial of XZP-5610 Tablets in Healthy Subjects
Status: UNKNOWN
Conditions: Nonalcoholic Steatohepatitis (NASH)
Interventions: DRUG: XZP-5610 Tablet (for Part A)|DRUG: Placebo to match XZP-5610 Tablet (for Part A)|DRUG: XZP-5610 Tablet (for Part B)|DRUG: Placebo to match XZP-5610 Tablet (for Part B)|DRUG: XZP-5610 Tablet （for "Part C1"）|DRUG: XZP-5610 Tablet for "Part C2"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of FODMAPs on Mucosal Inflammation in IBS Patients
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome With Diarrhea
Interventions: OTHER: Low FODMAP Diet followed by a High FODMAP Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Romidepsin, Gemcitabine, Dexamethasone and Cisplatin in the Treatment of Peripheral T-Cell and Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Peripheral T-Cell Lymphoma|Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Gemcitabine|DRUG: Dexamethasone|DRUG: Cisplatin|DRUG: Romidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Formative Development of a Multigenerational eHealth Intervention for Grandparents and Grandchildren
Status: WITHDRAWN
Conditions: Physical Inactivity
Interventions: OTHER: Multigenerational eHealth Intervention for Grandparents and Grandchildren
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Animation-Assisted Information Video Viewing on Fear and Anxiety in Children Before Endoscopy Procedure
Status: COMPLETED
Conditions: Endoscopy|Animation|Fear|Anxiety|Child
Interventions: BEHAVIORAL: Animated- assisted video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Electronic Cigarette Settings and Liquid Concentrations in Cigarette Smokers and Electronic Cigarette Users
Status: COMPLETED
Conditions: Electronic Cigarettes
Interventions: OTHER: ECIG Lab Session 15 watts, 10 mg nicotine|OTHER: ECIG Lab Session 15 watts, 15 mg nicotine|OTHER: ECIG Lab Session 15 watts, 30 mg nicotine|OTHER: ECIG Lab Session 30 watts, 10 mg nicotine|OTHER: ECIG Lab Session 30 watts, 15 mg nicotine|OTHER: ECIG Lab Session 30 watts, 30 mg nicotine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Seven Day Prucalopride Administration in Healthy Volunteers
Status: COMPLETED
Conditions: Molecular Mechanisms of Pharmacological Action|Depression|Depressive Disorder|Mood Disorders|Mental Disorders|Antidepressive Agents|Cognition
Interventions: DRUG: Prucalopride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anti-PD-1 Antibody Combined With Pegaspargase in the Treatment of Advanced Stage NK/T-cell Lymphoma
Status: UNKNOWN
Conditions: Nasal Type Extranodal NK/T-Cell Lymphoma
Interventions: DRUG: Pegaspargase|DRUG: Anti-PD-1 monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Fibrocaps in Liver Surgery in the Netherlands
Status: COMPLETED
Conditions: Postoperative Hemorrhage
Interventions: BIOLOGICAL: Fibrocaps (fibrin sealant)|DEVICE: Gelatin sponge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Regular Home Use of Lumoral Dual-light Photodynamic Therapy on Plaque Control and Gingival Health
Status: COMPLETED
Conditions: Periodontitis|Plaque, Dental|Plaque Induced Gingivitis
Interventions: DEVICE: Lumoral device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation Of Pessaries In Twin Pregnancies With A Short Cervix (25 mm) Between 20-28 WG (EPEGE)
Status: COMPLETED
Conditions: Twin Pregnancy
Interventions: DEVICE: Silicon ring positioned in the vagina, around the cervix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of the Efficacy of Intratumoral L19IL2 or L19TNF or L19IL2/L19TNF, in Combination With Pembrolizumab, in Unresectable Melanoma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma Stage III|Melanoma Stage IV
Interventions: DRUG: L19IL2|DRUG: L19TNF|DRUG: L19IL2/L19TNF|DRUG: KEYTRUDA®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Acting Injectable Naltrexone Treatment of Alcohol Dependence in Primary Care vs. in Specialized Chemical Dependence Treatment: A Pilot Trial
Status: TERMINATED
Conditions: Alcohol Dependence|Veterans
Interventions: DRUG: Injectable Naltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement of Soluble Factors and Particulate Matter in Induced Sputum and EBC in Inflammatory Diseases of the Lung
Status: COMPLETED
Conditions: Asthma|Chronic Obstructive Pulmonary Disease|Interstitial Lung Diseases|Occupational Lung Diseases
Interventions: OTHER: no generic names
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Value of Inhaled Treatment With Aztreonam Lysine in Bronchiectasis
Status: RECRUITING
Conditions: Bronchiectasis Adult
Interventions: DRUG: Aztreonam lysine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Samples to Identify Biomarkers in Patients Treated With Cyclophosphamide After Donor Stem Cell Transplant
Status: RECRUITING
Conditions: Allogeneic Hematopoietic Stem Cell Transplant Recipient|Donor|Malignant Neoplasm
Interventions: OTHER: Biospecimen Collection-Blood|OTHER: Biospecimen Collection-Stool
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Biofortified Maize to Improve Maternal and Infant Vitamin A Status
Status: COMPLETED
Conditions: Vitamin A Deficiency
Interventions: DIETARY_SUPPLEMENT: Conventional white maize|DIETARY_SUPPLEMENT: Provitamin A carotenoid biofortified maize|DIETARY_SUPPLEMENT: Preformed vitamin A fortified maize
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 18F-FMAU PET/CT in Diagnosing and Characterizing Prostate Cancer
Status: TERMINATED
Conditions: Prostate Neoplasm
Interventions: DEVICE: CAT|DRUG: 18F-FMAU|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Multiparametric Magnetic Resonance Imaging|DEVICE: Positron Emission Tomography|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate the Replacement of Reverse Transcriptase Nucleoside/Nucleotide Inhibitors by Nevirapine in Patients on Triple Treatment With Analogues Only
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nevirapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Motor Proteins on Muscle Atrophy in Cancer Patients
Status: UNKNOWN
Conditions: Cancer|Muscle Atrophy
Interventions: PROCEDURE: whole-body electromyostimulation WB-EMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of FTY720 for Acute Stroke
Status: COMPLETED
Conditions: Stroke|Vascular Accident|Cerebral Stroke|Ischemic Cerebrovascular Accident|Stroke, Acute
Interventions: DRUG: Fingolimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Efficacy of MTP-131 for Treatment of Mitochondrial Disease in Subjects From the MMPOWER Study
Status: COMPLETED
Conditions: Primary Mitochondrial Disease
Interventions: DRUG: Elamipretide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Drug Interactions Between Danicopan and Cyclosporine, Tacrolimus, Antacids, and Omeprazole in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Danicopan|DRUG: Cyclosporine|DRUG: Tacrolimus|DRUG: Calcium Carbonate|DRUG: Aluminum/Magnesium Hydroxide/Simethicone|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Ferumoxytol Enhanced MRI for Detecting Lymph Node Metastases in Prostate, Bladder, and Kidney Cancers
Status: COMPLETED
Conditions: Prostate Cancer|Bladder Cancer|Kidney Cancer
Interventions: DRUG: Ferumoxytol|DIAGNOSTIC_TEST: Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of GSK4527226 [AL101] in Participants With Early Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer's Disease
Interventions: DRUG: GSK4527226|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Otago Exercises and Otago Exercise Effects on Elderly Population
Status: NOT_YET_RECRUITING
Conditions: Elderly Population
Interventions: OTHER: Otago Exercise + Exer gaming|OTHER: exer gaming based programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of Potency of Cross-preconditioning to Prevent Ischemic-reperfusion Injury for Heart Transplantation Recipient
Status: UNKNOWN
Conditions: Ischemic Preconditioning
Interventions: PROCEDURE: cross-preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Health and Quality of Life Assessment Project for Caregivers of Idiopathic Pulmonary Fibrosis Patients
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis|Patient-caregiver Dyads
Interventions: OTHER: Caregiver Quality of Life Questionnaires|OTHER: Patient Quality of Life Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Evaluation and Intervention of Developmental Behavioral Diseases Based on Multicenter Cohort Study(CEIDBDBMCS)
Status: RECRUITING
Conditions: ADHD|Language Disorders
Interventions: OTHER: Functional Training.|OTHER: Observe.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Anesthetist Controlled Versus Patient-controlled Sedation: Risks and Benefits
Status: COMPLETED
Conditions: Patient Satisfaction
Interventions: DRUG: Midazolam-Fentanyl combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Neuraxial Analgesia on Maternal Breastfeeding
Status: COMPLETED
Conditions: Pain|Breastfeeding
Interventions: DRUG: Group 1|DRUG: Group 2|DRUG: Group 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Repeatability and Agreement of Anterior Segment Optical Coherence Tomography (AS-OCT) and Thermography
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DEVICE: EyeGiene
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effect of Intravenous Hyoscine Butylbromide Injection on Labour in High Risk Women
Status: COMPLETED
Conditions: Vaginal Delivery
Interventions: DRUG: hyoscine butylbromide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Position Given to Preterms After Feeding on Gastric Residual Volume, Abdominal Oxygenation and Fractional Oxygen Extraction
Status: RECRUITING
Conditions: Gastric Residual Volume|Abdominal Oxygenation|Fractional Oxygen Extraction|Positioning (Prone, Right Lateral and Semi-Elevated Supine Position)
Interventions: OTHER: Prone, right lateral, and semi-elevated supine positions|OTHER: Semi-elevated supine, prone, and right lateral positions|OTHER: Right lateral, semi-elevated supine, and prone positions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assess Bioequivalence of Two Formulations of Doxorubicin Hydrochloride Liposome in Female Patients With Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Doxorubicin hydrochloride liposome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptive, Image-guided, Intensity-modulated Radiotherapy for Head and Neck Cancer in the Reduced Volumes of Elective Neck
Status: COMPLETED
Conditions: Primary Non-operated Squamous Cell Carcinoma of Oral Cavity|Primary Non-operated Squamous Cell Carcinoma of Oropharynx|Primary Non-operated Squamous Cell Carcinoma of Hypopharynx|Primary Non-operated Squamous Cell Carcinoma of Larynx
Interventions: PROCEDURE: video fluoroscopy|PROCEDURE: extra imaging|OTHER: scoring acute toxicity|OTHER: scoring of late toxicity|OTHER: scoring quality of life (QOL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Dietary Phosphate and Mineral Homeostasis in Early Chronic Kidney Disease
Status: COMPLETED
Conditions: Kidney Diseases
Interventions: BEHAVIORAL: High/ Low Phosphate diet|BEHAVIORAL: High/ Low Phosphate diet|BEHAVIORAL: High/ Low Phosphate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Analgesic Consumption Between Perioperative ıv Dexamethasone and Added to Femoral Block
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: iv dexamethasone|DRUG: femoral dexamethasone|DRUG: serum physiologic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Organ Protection for Coronary Artery Bypass Graft (CABG): Propofol Versus Desflurane
Status: COMPLETED
Conditions: Coronary Artery Bypass|Delirium|Dementia|Amnesia|Cognition Disorders|Morbidity
Interventions: DRUG: propofol|DRUG: desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of Stimulator Pneumatic for Realization of Evoked Potential Allodynic/Somatosensory
Status: TERMINATED
Conditions: Neuropathic Pain
Interventions: OTHER: pneumatic stimulations(allodynic area)|OTHER: pneumatic stimulations (healthy area)|OTHER: pneumatic stimulations no auditory masking|OTHER: no stimulation (control)|OTHER: pneumatic stimulations with audidory masking
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Oral Suberoylanilide Hydroxamic Acid (Vorinostat) in Patients With Solid Tumors (0683-048)
Status: COMPLETED
Conditions: Tumors
Interventions: DRUG: Vorinostat|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of an Oral Mixture of Arginine, Glutamine and Beta-hydroxy-beta-methylbutyrate for Treatment of Pressure Ulcers
Status: UNKNOWN
Conditions: Pressure Ulcers Stage III|Pressure Ulcer, Stage IV
Interventions: DIETARY_SUPPLEMENT: ABOUND
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Reactogenicity and Immunogenicity of a Novel MVA-SARS-2-ST Vaccine Candidate
Status: TERMINATED
Conditions: COVID-19 Vaccines
Interventions: BIOLOGICAL: MVA-SARS-2-ST
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of a Telehomecare Program for Young Patients With New Onset Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Telehomecare (Intelligent Distance Patient Monitoring)|OTHER: Standard education and follow up at diabetes clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Cohort Study of Beta-Glucan or Beta-Glucan Compound in Metastatic Cancers
Status: UNKNOWN
Conditions: Metastatic Cancer|Chemotherapy
Interventions: DIETARY_SUPPLEMENT: Beta-Glucan|DIETARY_SUPPLEMENT: Glutamine|DIETARY_SUPPLEMENT: Immunoglobuin|DIETARY_SUPPLEMENT: Corn starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Ingavirin®, Syrup, 30 mg/5 ml, in Children With Influenza and Other Acute Respiratory Viral Infections
Status: COMPLETED
Conditions: Influenza, Human|Acute Respiratory Infection|Common Cold
Interventions: DRUG: Ingavirin®, syrup, 30 mg/5 ml|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Safety and Effectiveness of CURVE Laser Therapy for Circumference Reduction of the Waistline.
Status: COMPLETED
Conditions: Injury to Subcutaneous Tissue
Interventions: DEVICE: Curve Low Level Laser Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dual Tasking on Physical and Cognitive Functions in Patients With Parkinson Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: OTHER: Dual task|OTHER: Treadmill Training|OTHER: Standard exercise programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Neoadjuvant Folfirinox Regimen in Patients With Resectable Locally Advanced Rectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer of the Rectum
Interventions: DRUG: mFolfirinox|RADIATION: Radiotherapy 50 Gy|DRUG: Capecitabine|PROCEDURE: TME surgery|DRUG: mFolfox6 or capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of NX-1207 for the Treatment of Benign Prostatic Hyperplasia (BPH) NX02-0018
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia (BPH)
Interventions: DRUG: NX-1207|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Conivaptan (Vaprisol) for Hyponatremic Neuro-ICU Patients
Status: TERMINATED
Conditions: Hyponatremia
Interventions: DRUG: Conivaptan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT