pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study to Evaluate Ospemifene in Patients With Moderate to Severe Vaginal Dryness Due to Menopause
Status: COMPLETED
Conditions: Vaginal Dryness
Interventions: DRUG: Ospemifene|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Assess The Safety Of PF-05335810 In Hypercholesterolemic Subjects
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: BIOLOGICAL: PF-05335810 Dose A|BIOLOGICAL: PF-05335810 Dose B|BIOLOGICAL: Placebo|BIOLOGICAL: PF-05335810 Dose B|BIOLOGICAL: Placebo|BIOLOGICAL: PF-04950615 Dose A|BIOLOGICAL: PF-04950615 Dose A|BIOLOGICAL: PF-05335810 Dose C|BIOLOGICAL: Placebo|BIOLOGICAL: PF-05335810 Dose C|BIOLOGICAL: Placebo|BIOLOGICAL: PF-04950615|BIOLOGICAL: PF-05335810 Dose D|BIOLOGICAL: Placebo|BIOLOGICAL: PF-05335810 Dose E|BIOLOGICAL: PF-05335810 Dose D|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Simple Clinical Tool to Help Diagnose Pulmonary Embolism: Phase 1
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Embolism
Interventions: OTHER: Augmented pulse oximetry using incentive spirometer.|DEVICE: Incentive spirometer.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Non Interventional Study With Primary Open Angle Glaucoma and/or Ocular Hypertension Patients Treated With Xalacom® After Failure of Previous Antiglaucoma Therapy.
Status: COMPLETED
Conditions: Glaucoma, Open-angle
Interventions: DRUG: Xalacom
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of HQGZWWT Patients With Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Huang Qi Gui Zhi Wu Wu Granule|Rheumatoid Arthritis
Interventions: DRUG: Huang qi gui zhi wu wu granule|DRUG: Huang qi gui zhi wu wu granule placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of a Sexual Assault Resistance Program for Adolescent Girls
Status: RECRUITING
Conditions: Sexual Assault
Interventions: BEHAVIORAL: A-EAAA Sexual Assault Resistance Education Program immediately|BEHAVIORAL: Usual care + A-EAAA at 6 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of the Safety and Activity of the MEK Inhibitor Given Together With the AKT Inhibitor to Patients With Multiple Myeloma or Solid Tumor Cancers
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: GSK1120212|DRUG: GSK2110183
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Efficacy of Image-guided Laser-assisted Enstilar® Delivery for Treatment of Psoriatic Nails
Status: COMPLETED
Conditions: Nail Psoriasis
Interventions: DRUG: Enstilar|DEVICE: Ablative fractional laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Market Clinical Follow-Up Study - Medical Device KalobaGOLA ( PMCF )
Status: COMPLETED
Conditions: Sore-throat|Pharyngitis
Interventions: DEVICE: KalobaGOLA spray (1)|DEVICE: KalobaGOLA spray (2)|DEVICE: KalobaGOLA tablets
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: iNOS With Positron Emission Tomography (PET) in Cellular Inflammation.
Status: COMPLETED
Conditions: Patients With Post Orthotopic Heart Transplantation Status
Interventions: DRUG: [18F](+/-)NOS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetics of Somatropin in Patients With End Stage Renal Disease Receiving Chronic Haemodialysis
Status: COMPLETED
Conditions: Chronic Kidney Disease|End-Stage Renal Disease|Healthy
Interventions: DRUG: somatropin|DRUG: somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: WT1 Analog Peptide Vaccine in Patients With Multiple Myeloma Following Autologous Stem Cell Transplantation
Status: UNKNOWN
Conditions: Multiple Myeloma|Minimal Residual Disease|High-Risk Cancer
Interventions: BIOLOGICAL: WT1 Analog Peptide Vaccine|BIOLOGICAL: Sargramostim (GM-CSF)|DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Sensory Enrichment Multimodal Device (SEMD) on Physical Therapy Patients With Disequilibrium
Status: COMPLETED
Conditions: Vestibular Diseases|Labyrinth Diseases|Ear Diseases|Otorhinolaryngologic Diseases|Traumatic Brain Injury
Interventions: DEVICE: Usual care physical therapy plus SEMD|OTHER: Usual care physical therapy only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adductor Under Sartorial Canal Catheter (KTT) Versus Femoral Catheter (KTF) in a Quick Rehabilitation Process After Total Knee Replacement
Status: COMPLETED
Conditions: Total Knee Replacement
Interventions: DEVICE: under sartorial catheter|DEVICE: femoral catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Is There Benefit From Early Postoperative PTH Monitoring?
Status: UNKNOWN
Conditions: Hypocalcemia|Thyroid|Postoperative Complications|Parathyroid Dysfunction|Hormone Disturbance
Interventions: DIAGNOSTIC_TEST: Immediate postoperative PTH serum sampling and cut-off value identification
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vaginal Micronized Progesterone Versus Levonorgestrel for Treatment of Non-atypical Endometrial Hyperplasia
Status: COMPLETED
Conditions: Endometrial Hyperplasia Without Atypia
Interventions: DRUG: Vaginal Micronized Progesterone|DEVICE: Levonorgestrel-Intrauterine System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Two or Five cm From Pylorus During Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: PROCEDURE: laparoscopic sleeve gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Colpocleisis for Advanced Pelvic Organ Prolapse
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|Stress Urinary Incontinence
Interventions: PROCEDURE: Colpocleisis prolapse repair surgery|PROCEDURE: sling or other to treat or prevent stress incontinence
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial to Evaluate the Safety and Efficacy of Ciprofloxacin in the Treatment of Plague in Humans
Status: UNKNOWN
Conditions: Plague
Interventions: DRUG: ciprofloxacin|DRUG: doxyxcycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Thymoglobulin in Paediatric Haematopoietic Stem-cell Transplants
Status: TERMINATED
Conditions: Malignancy|Metabolic Disease|Genetic Disorder
Interventions: BIOLOGICAL: Thymoglobulin (rATG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-administered Acupressure for Knee Osteoarthritis in Middle- and Older-Aged Adults
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Self-administered acupressure treatment group|OTHER: Knee health education control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Sonrotoclax in Participants With Waldenström's Macroglobulinemia
Status: RECRUITING
Conditions: Waldenstrom Macroglobulinemia|Waldenstrom's Macroglobulinemia Recurrent|Waldenstrom's Macroglobulinemia Refractory
Interventions: DRUG: BGB-11417|DRUG: Zanubrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INTERvention With Cerebral Embolic Protection in Transcatheter Aortic Valve Implantation (INTERCEPTavi)
Status: RECRUITING
Conditions: Stroke|Aortic Valve Stenosis|Silent Cerebral Infarct|Vascular Brain Injury
Interventions: OTHER: CO2 and saline flushing|OTHER: Saline flushing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: HV Electrophysiology Study In Transcatheter Aortic Valve Implantation Patients
Status: UNKNOWN
Conditions: Left Bundle Branch Block|Transcatheter Aortic Valve Replacement|Transcatheter Aortic Valve Implantation
Interventions: OTHER: HV measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acupuncture or Standard Therapy in Treating Pain and Dysfunction in Patients Who Have Undergone Neck Surgery for Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Pain
Interventions: PROCEDURE: acupuncture therapy|PROCEDURE: standard follow-up care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-invasive Neurally Adjusted Ventilatory Assist Versus Nasal Intermittent Positive Pressure Ventilation for Preterm Infants After Extubation
Status: COMPLETED
Conditions: Prematurity|Respiratory Failure|Ventilator Lung; Newborn
Interventions: DEVICE: NI-NAVA|DEVICE: NIPPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ValoRization of Dairy Sidestreams to Fight Calcium dEficits iN Postmenopausal Women
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DIETARY_SUPPLEMENT: Maltodextrin|DIETARY_SUPPLEMENT: Calcium-carbonate|DIETARY_SUPPLEMENT: Calcium-enriched permeate|DIETARY_SUPPLEMENT: Calcium-enriched permeate with Inulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Soap Versus Normal Salin Plus Povidone-iodine in Ununion Wound
Status: UNKNOWN
Conditions: Wound
Interventions: DRUG: water and soap|DRUG: Povidone-iodine And normal salin treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Family-Based Treatment for Parental Substance Abuse and Child Maltreatment
Status: COMPLETED
Conditions: Substance Abuse|Child Abuse|Child Neglect
Interventions: BEHAVIORAL: Comprehensive Community Treatment|BEHAVIORAL: MST-BSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Central Corneal Swelling With Silicone Hydrogel Materials
Status: COMPLETED
Conditions: Corneal Swelling
Interventions: DEVICE: etafilcon A|DEVICE: lotrafilcon B|DEVICE: comfilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Long-term Safety and Clinical Activity of mRNA-3927 in Participants Previously Enrolled in the mRNA-3927-P101 Study
Status: RECRUITING
Conditions: Propionic Acidemia
Interventions: BIOLOGICAL: mRNA-3927
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tolerability and Efficacy of Cannabidiol on Motor Symptoms in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Cannabidiol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Topical Lidocaine to Decrease Discomfort With Intranasal Midazolam Administration
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Lidocaine|DRUG: Midazolam|DRUG: 0.9% Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Angioplasty and Stenting for Patients With Symptomatic Intracranial Atherosclerosis
Status: UNKNOWN
Conditions: Intracranial Atherosclerosis
Interventions: PROCEDURE: Percutaneous transluminal angioplasty and stenting|DRUG: Aspirin plus clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Supplementing Hearing Aids With Computerized Auditory Training
Status: COMPLETED
Conditions: Hearing Loss
Interventions: BEHAVIORAL: LACE-computer|BEHAVIORAL: PLACEBO-Directed listening|BEHAVIORAL: CONTROL|BEHAVIORAL: Lace-DVD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioavailability of Desipramine Hydrochloride 50 mg Tablets
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Desipramine Hydrochloride 50 mg Tablets (Cord Laboratories)|DRUG: Desipramine Hydrochloride 50 mg Tablets (Merrell Dow Pharmaceuticals, Inc)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: to Evaluate the Preliminary Efficacy and Safety of GR1501 Injection in Patients With Active Axial Spondyloarthritis
Status: COMPLETED
Conditions: Axial Spondyloarthritis
Interventions: BIOLOGICAL: IL-17A antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Live Attenuated Japanese Encephalitis Vaccine (ChimeriVax™-JE) and Yellow Fever Vaccine (STAMARIL®)
Status: COMPLETED
Conditions: Japanese Encephalitis|Yellow Fever
Interventions: BIOLOGICAL: Live attenuated Japanese encephalitis virus; Yellow fever virus|BIOLOGICAL: Yellow fever virus; Live attenuated Japanese encephalitis virus|BIOLOGICAL: Live attenuated Japanese encephalitis virus; Yellow fever virus|BIOLOGICAL: Live attenuated Japanese encephalitis virus; Yellow fever virus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Combination With Lucentis® in Patients With Age-Related Macular Degeneration
Status: TERMINATED
Conditions: Age-Related Macular Degeneration|Choroidal Neovascularization
Interventions: DRUG: Sirolimus in combination with ranibizumab|DRUG: Sirolimus in combination with ranibizumab|DRUG: Placebo in combination with ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Drug-coated Angioplasty Balloons in the Superficial Femoral or Popliteal Arteries:
Status: COMPLETED
Conditions: Peripheral Artery Disease
Interventions: DEVICE: Angioplasty treatment with the CVI Drug-coated Balloon (DCB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab/Lenvatinib With and Without Responder-derived FMT in Relapsed/Refractory Melanoma
Status: NOT_YET_RECRUITING
Conditions: PD-1 Refractory Advanced Melanoma
Interventions: BIOLOGICAL: Responder-Derived Fecal microbiota transplantation (R-FMT|DRUG: Pembrolizumab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Newborn Infant Parasympathetic Evaluation (NIPE) Index After Standardized Tetanic Stimulations Under General Anesthesia
Status: COMPLETED
Conditions: Anesthesia
Interventions: DEVICE: NIPE monitor|PROCEDURE: Tetanic stimulations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Investigating the Efficacy and Safety of a Contraceptive Patch for 13 Cycles
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Gestodene/EE Patch (BAY86-5016)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Acupuncture for Symptoms of Nerve Damage
Status: COMPLETED
Conditions: Peripheral Neuropathy|Chemotherapy-induced Peripheral Neuropathy
Interventions: PROCEDURE: Acupuncture|PROCEDURE: Sham Acupuncture|OTHER: Usual Care Group|BEHAVIORAL: questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Temozolomide in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: temozolomide|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Cholecystectomy is Not Mandatory in Patients Candidate to the Resection for Small Intestine Neuroendocrine Neoplasms: a Propensity Score-matched and Cost-minimization Analysis
Status: COMPLETED
Conditions: Neuroendocrine Tumors|Surgery|Gut Tumor
Interventions: PROCEDURE: Cholecystectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nasal High-frequency Jet Ventilation (nHFJV) Following Extubation in Preterm Infants
Status: TERMINATED
Conditions: Infant,Premature|Respiratory Failure|Respiratory Insufficiency|Respiratory Distress Syndrome in Premature Infant
Interventions: OTHER: Nasal high-frequency jet ventilation (nHFJV)|OTHER: Nasal intermittent positive pressure ventilation (NIPPV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Aromatherapy on Perioperative Anxiety Level in Cesarean Sections
Status: COMPLETED
Conditions: Anxiety|Midazolam Overdose|Breast Feeding
Interventions: OTHER: Aromatherapy|OTHER: Placebo oil (odorless baby oil- jojoba and almond oil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized Phase III Trial Comparing Folfirinox to Gemcitabine in Locally Advanced Pancreatic Carcinoma
Status: COMPLETED
Conditions: Pancreatic Cancer|Carcinoma
Interventions: DRUG: Gemcitabine|DRUG: Folinic Acid|DRUG: 5-Fluoro-uracil|DRUG: Oxaliplatin|DRUG: Irinotecan|DRUG: L-folinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closed-loop Control of Glucose Levels (Artificial Pancreas) for 24 Hours in Adults and Adolescents With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: OTHER: Closed-loop system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Placebo-Controlled Trial of Stellate Ganglion Block in the Treatment of Post Traumatic Stress Disorder
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder (PTSD)
Interventions: PROCEDURE: Stellate Ganglion Block injection with ropivicane|PROCEDURE: Placebo Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrated Platform for Measuring and Reducing Symptoms of Autism Spectrum Disorder
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: Cognilum TM: Light Treatment Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Registry of Eosinophilia With Respiratory Manifestations With Translational Research Identifying and Characterizing Eosinophils
Status: RECRUITING
Conditions: Eosinophilic Asthma|EGPA - Eosinophilic Granulomatosis With Polyangiitis|Samter Triad|HES - Hypereosinophilic Syndrome|Eosinophilic Pneumonia
Interventions: OTHER: no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sexual Health Counseling Intervention During Radiation Therapy in Improving Quality of Life for Women With Gynecologic Cancer
Status: COMPLETED
Conditions: Malignant Female Reproductive System Neoplasm|Stage I Cervical Cancer AJCC v8|Stage I Uterine Corpus Cancer AJCC v8|Stage I Vaginal Cancer AJCC v8|Stage I Vulvar Cancer AJCC v8|Stage IA Cervical Cancer AJCC v8|Stage IA Uterine Corpus Cancer AJCC v8|Stage IA Vaginal Cancer AJCC v8|Stage IA Vulvar Cancer AJCC v8|Stage IA1 Cervical Cancer AJCC v8|Stage IA2 Cervical Cancer AJCC v8|Stage IB Cervical Cancer AJCC v8|Stage IB Uterine Corpus Cancer AJCC v8|Stage IB Vaginal Cancer AJCC v8|Stage IB Vulvar Cancer AJCC v8|Stage IB1 Cervical Cancer AJCC v8|Stage IB2 Cervical Cancer AJCC v8|Stage II Cervical Cancer AJCC v8|Stage II Uterine Corpus Cancer AJCC v8|Stage II Vaginal Cancer AJCC v8|Stage II Vulvar Cancer AJCC v8|Stage IIA Cervical Cancer AJCC v8|Stage IIA Vaginal Cancer AJCC v8|Stage IIA1 Cervical Cancer AJCC v8|Stage IIA2 Cervical Cancer AJCC v8|Stage IIB Cervical Cancer AJCC v8|Stage IIB Vaginal Cancer AJCC v8|Stage III Cervical Cancer AJCC v8|Stage III Uterine Corpus Cancer AJCC v8|Stage III Vaginal Cancer AJCC v8|Stage III Vulvar Cancer AJCC v8|Stage IIIA Cervical Cancer AJCC v8|Stage IIIA Uterine Corpus Cancer AJCC v8|Stage IIIA Vulvar Cancer AJCC v8|Stage IIIB Cervical Cancer AJCC v8|Stage IIIB Uterine Corpus Cancer AJCC v8|Stage IIIB Vulvar Cancer AJCC v8|Stage IIIC Uterine Corpus Cancer AJCC v8|Stage IIIC Vulvar Cancer AJCC v8|Stage IIIC1 Uterine Corpus Cancer AJCC v8|Stage IIIC2 Uterine Corpus Cancer AJCC v8|Stage IVA Cervical Cancer AJCC v8|Stage IVA Uterine Corpus Cancer AJCC v8|Stage IVA Vaginal Cancer AJCC v8|Stage IVA Vulvar Cancer AJCC v8
Interventions: OTHER: Counseling|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Hydrotherapy in Pain and Quality of Sleep's Cycles in Preterm Newborn on Neonatal Intensive Care Units
Status: UNKNOWN
Conditions: Perinatal Care
Interventions: OTHER: Aquatic Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I Trial of Selinexor (KPT-330) and Ifosfamide, Carboplatin, Etoposide (ICE) in Peripheral T-cell Lymphoma
Status: COMPLETED
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: Selinexor|DRUG: ICE Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib and Transarterial Chemoembolization for Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sorafenib|PROCEDURE: Transarterial chemoembolisation (TACE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subacromial Injection of Allogeneic Platelet Rich Plasma (PRP) for Shoulder Impingement Syndrome
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome
Interventions: PROCEDURE: Steroid injection into the subacromial space|PROCEDURE: Allogeneic PRP injection into the subacromial space
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diaphragm Activity During Incentive Spirometry and Diaphragmatic Breathing
Status: COMPLETED
Conditions: Diaphragm Mobility|Breathing Exercises|Incentive Spirometry|Diaphragmatic Breathing
Interventions: DEVICE: DB, VI and FI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Economic Evaluation of Glass Ionomer Material Using as Dental Sealant
Status: COMPLETED
Conditions: Glass Ionomer Cement|Cost-effectiveness|Pit and Fissure Caries (Disorder)
Interventions: DRUG: resin sealant|DRUG: ART sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Immune Response Under Immunotherapy in Metastatic NSCLC: Sputum, Blood Samples and Microbioata Study
Status: COMPLETED
Conditions: Non-squamous Lung Cancer|Metastatic Lung Cancer
Interventions: OTHER: Blood|OTHER: sputum|OTHER: saliva|OTHER: stool
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Interleukin-2 (IL-2) Combined With Rituximab (Rituxan) to Rituximab Alone in Subjects With Non-Hodgkin's Lymphoma (NHL)
Status: TERMINATED
Conditions: Non-Hodgkin Lymphoma
Interventions: DRUG: interleukin-2|DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rivastigmine Monotherapy and Combination Therapy With Memantine in Patients With Moderately Severe Alzheimer's Disease Who Failed to Benefit From Previous Cholinesterase Inhibitor Treatment
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Rivastigmine, memantine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Active and Placebo-controlled Study of Enteric Coated Sevelamer in Patients With Mild to Moderate Hypercholesteremia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Enteric coated sevelamer|DRUG: Enteric coated sevelamer|DRUG: Colesevelam Cholestagel|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetic Study of Lumacaftor/Ivacaftor in Participants 1 to Less Than 2 Years of Age With Cystic Fibrosis, Homozygous for F508del
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: LUM|DRUG: IVA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapy to Improve Reaching Movement in Upper Limb
Status: UNKNOWN
Conditions: Stroke|Impairment Upper Limb
Interventions: OTHER: Neuromodulation electroencephalographic signals and functional electrical stimulation based
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Post-isometric Relaxation Technique and Static Stretching on Length of the Calf Muscles in Post-CABG Patients
Status: UNKNOWN
Conditions: Coronary Artery Bypass
Interventions: PROCEDURE: post-isometric relaxation technique|PROCEDURE: Static stretching|PROCEDURE: Basic Cardiac Rehabilitation Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Chronobiologic Feeding Model on Circadian Rhythm in Newborns
Status: RECRUITING
Conditions: Breast Feeding, Exclusive|Hospitalization|Feeding Patterns
Interventions: OTHER: Feeding model group with a chronobiological approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Effect of Life With Food Allergy Education
Status: NOT_YET_RECRUITING
Conditions: FOOD ALLERGY|FOOD ALLERGY İN CHİLDREN
Interventions: BEHAVIORAL: Face to face group|BEHAVIORAL: social mediagroup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 24-Hour NAVA Ventilation in Acute Respiratory Failure
Status: COMPLETED
Conditions: Respiration, Artificial|Respiratory Insufficiency
Interventions: DEVICE: Neurally Adjusted Ventilatory Assist (NAVA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Radiation Therapy Alone Compared to Radiation Therapy Plus Chemotherapy in Treating Patients With Previously Untreated Cancer of the Nasopharynx
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: DRUG: cisplatin|DRUG: fluorouracil|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of ALD-401 Via Intracarotid Infusion in Ischemic Stroke Subjects
Status: UNKNOWN
Conditions: Stroke|Ischemic Stroke|Stroke in Middle Cerebral Artery (MCA)
Interventions: BIOLOGICAL: ALD-401|PROCEDURE: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of OCTAPLEX in Patients With Acute Major Bleeding on DOAC Therapy With Factor Xa Inhibitor
Status: RECRUITING
Conditions: Acute Major Bleeding
Interventions: DRUG: Octaplex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Novel Working Memory Training Program to Decrease Symptoms of PTSD
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: OTHER: Computerized Cognitive Training - active|OTHER: Computerized cognitive training - sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Double-blind, Randomized, Placebo-controlled Study in Psoriasis Patients
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: DLX105 Hydrogel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid Response Teams - How and Who?
Status: NOT_YET_RECRUITING
Conditions: Hospital Rapid Response Team|Early Warning Score|Intensive Care Units
Interventions: OTHER: Rapid Response Team Composition_ ICU Nurse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of DA-9401 on Improvement of Sperm Motility
Status: COMPLETED
Conditions: Spermatocele
Interventions: DIETARY_SUPPLEMENT: DA-9401|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Pyrotinib Plus Capecitabine in Patients With HER2+ Metastatic Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2 Positive Metastatic Breast Cancer
Interventions: DRUG: pyrotinib|DRUG: placebo|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Digital Lifestyle Intervention For Diabetes/Pre-Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes|PreDiabetes|Obesity
Interventions: BEHAVIORAL: Digital Intensive Lifestyle Intervention|BEHAVIORAL: Digital Self-Help Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serum FGF21 Levels and Dietary Total Antioxidant Capacity in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Type 2 Diabetes Diet Modification
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: An Evaluation of the Safety and Efficacy of FID 114657
Status: COMPLETED
Conditions: Dry Eye
Interventions: OTHER: FID 114657|OTHER: Soothe XP Lubricant Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Small Tonsils
Status: NOT_YET_RECRUITING
Conditions: Otolaryngological Disease|Obstructive Sleep Apnea
Interventions: PROCEDURE: DISE-Directed Surgery|PROCEDURE: Adenotonsillectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dexmedetomidine on Breast Cancer Cell Function in Vitro
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Dexmedetomidine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Osteoblastic Cells Implantation to Early Stage Osteonecrosis of the Femoral Head
Status: COMPLETED
Conditions: Avascular Necrosis of Femur Head
Interventions: DRUG: Core decompression/PREOB® implantation|DRUG: Core decompression/BMC implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Extruded Cereals Enriched With β-glucan on Postprandial Plasma Glucose and Serum Insulin Responses
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: OTHER: Control Cereal|OTHER: OBG Cereal|OTHER: BBG Cereal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Irinotecan and Alisertib in Treating Patients With Advanced Solid Tumors or Colorectal Cancer
Status: COMPLETED
Conditions: Mucinous Adenocarcinoma of the Colon|Mucinous Adenocarcinoma of the Rectum|Recurrent Colon Cancer|Recurrent Rectal Cancer|Signet Ring Adenocarcinoma of the Colon|Signet Ring Adenocarcinoma of the Rectum|Stage IIIA Colon Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: irinotecan hydrochloride|DRUG: alisertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrafiltration Versus Intravenous (IV) Diuretics for Patients Hospitalized for Acute Decompensated Heart Failure: (UNLOAD)
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DEVICE: Aquadex system|DRUG: IV diuretic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Root Resorption and Dentin Sialoprotein Upon Application of Different Orthodontic Forces.
Status: UNKNOWN
Conditions: Root Resorption
Interventions: PROCEDURE: Orthodontic intrusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mum Can I Have Vegetables Again? Development of Vegetable Preferences
Status: COMPLETED
Conditions: Vegetable Intake After Weaning With Vegetables or Fruits|Fruit Intake After Weaning With Vegetables or Fruits
Interventions: OTHER: green beans group|OTHER: Artichoke group|OTHER: Apple group|OTHER: Plums group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Posoleucel (ALVR105, Formerly Viralym-M) for Multi-Virus Prevention in Patients Post-Allogeneic Hematopoietic Cell Transplant
Status: COMPLETED
Conditions: Adenovirus Infection|BK Virus Infection|Cytomegalovirus Infections|Epstein-Barr Virus Infections|Human Herpes Virus-6 Infection|JC Virus Infection
Interventions: BIOLOGICAL: Posoleucel (ALVR105)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Study of Drug SCT510A in Patients With Wet Age-related Macular Degeneration (wAMD)
Status: UNKNOWN
Conditions: Wet Age-related Macular Degeneration
Interventions: DRUG: SCT510A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auricular Acupressure for Chemotherapy-Induced Nausea and Vomiting in Female Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Neoplasms|Nausea|Vomiting
Interventions: DEVICE: True auricular acupressure|DEVICE: Sham auricular acupressure|DRUG: Standard anti-emetic treatment (5-HT3 receptor antagonists and/or Dexamethasone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-Fluoroazomycin Arabinoside PET-CT in Diagnosing Solid Tumors in Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Breast Neoplasm|Malignant Colorectal Neoplasm|Malignant Pancreatic Neoplasm|Malignant Solid Neoplasm
Interventions: PROCEDURE: Computed Tomography|RADIATION: Fluorine F 18-fluoroazomycin Arabinoside|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safe Access: Trial With RemovAid Device
Status: COMPLETED
Conditions: Removal of a Contraceptive Subdermal Implant
Interventions: DEVICE: RemovAid device + lidocaine patch|PROCEDURE: Standard technique + lidocaine injection|DEVICE: RemovAid device + lidocaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation Apparatus for Domiciliary Use
Status: COMPLETED
Conditions: Transcranial Direct Current Stimulation|Healthy Participants
Interventions: DEVICE: Active tDCS Ambulatory|DEVICE: Sham tDCS Ambulatory|DEVICE: Active tDCS Home use|DEVICE: Sham tDCS Home use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Evaluation of Therapeutic Video Games for Pre-school Children With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Childhood Lymphoblastic Lymphoma
Interventions: OTHER: TVG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Atorvastatin/CoenzymeQ10 in Congestive Heart Failure
Status: UNKNOWN
Conditions: Congestive Heart Failure
Interventions: DRUG: Atorvastatin|DRUG: Coenzyme Q10|DRUG: placebo for coenzyme Q10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Hospital Wide Roll-Out of Antimicrobial Stewardship
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: OTHER: Antibiotic stewardship audit-and-feedback to prescribers of patients receiving 3rd or 10th day of targeted broadspectrum antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Optimising Ventilation in Preterms With Closed-loop Oxygen Control
Status: RECRUITING
Conditions: Infant, Premature, Diseases|Airway Morbidity|Mechanical Ventilation Complication
Interventions: DEVICE: Closed-loop automated oxygen control (Oxygenie, SLE 6000)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Preoperative Smoking Cessation in Patients Undergoing Surgery
Status: RECRUITING
Conditions: Smoking Cessation|Smoking Reduction|Surgery--Complications|Surgery|Cancer|Postoperative Complications|Perioperative Complication|Smoking|Abdominal Cancer|Thoracic Cancer|Urologic Cancer|Gynecologic Cancer|Head and Neck Cancer
Interventions: BEHAVIORAL: Intensive preoperative smoking cessation counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiotherapy in Combination With Atezolizumab Prior to Surgical Resection for HPV Unrelated HNSCC
Status: SUSPENDED
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: Atezolizumab|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Detraining in Endurance Athletes With Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: BEHAVIORAL: Detraining group|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Accuracy of Shear-Wave Elastography for the Preoperative Risk Stratification of Follicular Lesions of the Thyroid
Status: COMPLETED
Conditions: Thyroid Nodule|Follicular Neoplasm
Interventions: DEVICE: Shear-Wave Elastography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Low-dose High-frequency Training of Facility Health Care Providers in Mali
Status: COMPLETED
Conditions: Perinatal Mortality
Interventions: OTHER: Usual Training|OTHER: Audits + LDHF Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Personalised Activity Plan for BREAKing UP Sitting Time in Patients With Peripheral Arterial Disease and Intermittent Claudication (The BREAK UP Study)
Status: UNKNOWN
Conditions: Peripheral Arterial Disease
Interventions: BEHAVIORAL: Activity plan to break up sitting time
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ruminant Trans Fats and the Risk of Cardiovascular Disease in Women
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: OTHER: isocaloric for week diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assesment of Two Different Modalities of Maxillary Canine Retraction Assisted With Injectable Platelet Rich Fibrin
Status: ENROLLING_BY_INVITATION
Conditions: Effect of Platelet Rich Fibrin Tooth Movement
Interventions: BIOLOGICAL: Injectable platelet rich fibrin .|BIOLOGICAL: Injectable platelet rich fibrin .
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Running Shoe Sole Hardness on Vibration and Neuromuscular Fatigue During a Half-marathon Run on a Treadmill
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: "hard shoes" runners evaluation|OTHER: "Soft shoes" runners evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Gemcitabine and Pulse Dose Erlotinib in Second Line Treatment of Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Mass Balance and Biotransformation of [14C]SHR1459 in Healthy Adult Male Volunteers
Status: UNKNOWN
Conditions: Healthy Adult Male Volunteers
Interventions: DRUG: [14C]SHR1459
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of DB-1303/BNT323 vs Investigator's Choice Chemotherapy in HER2-Low, Hormone Receptor Positive Metastatic Breast Cancer (DYNASTY-Breast02)
Status: RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: DB-1303/BNT323|DRUG: Capecitabine|DRUG: Paclitaxel|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Utility of Wound Vacuum Assisted Closure (VAC) Compared to Conventional Saline Dressing Changes
Status: TERMINATED
Conditions: Wounds|Compartment Syndromes
Interventions: DEVICE: Wound Care -Wound Vacuum Assisted Closure (VAC)|PROCEDURE: Wound Care - Wet to Dry Dressing Changes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GAGE Act With Her-Ethiopia Evaluation
Status: ACTIVE_NOT_RECRUITING
Conditions: Adolescent Behavior|Gender
Interventions: BEHAVIORAL: Her Spaces|BEHAVIORAL: Act With Her|BEHAVIORAL: Act With Her + Asset Transfer|BEHAVIORAL: Act With Her (simple)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT