pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of [11C]Cimbi-36 as an Agonist PET Radioligand for Imaging of 5-HT2A Receptors
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Citalopram and Pindolol|OTHER: Placebo|DIETARY_SUPPLEMENT: Acute tryptophan depletion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Anemia With Epoetin Beta in Low Risk Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Epoetin beta (NeoRecormon)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TXT2HEART COLOMBIA: Evaluation of the Efficacy and Safety of Text Messages to Improve Adherence to Cardiovascular Medications in Secondary Prevention
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: BEHAVIORAL: Intervention SMS|BEHAVIORAL: Control SMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Safety and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Influenza Vaccines GSK2654911A and GSK2654909A Administered to Adults 18 to 64 Years of Age
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Investigational H9N2 vaccine GSK2654911A|BIOLOGICAL: Investigational H9N2 vaccine GSK2654909A|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bcl-XL_42-CAF09b Vaccination for Patients With Prostate Cancer With Lymph Node Metastases
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Bcl-Xl_42-CAF09b vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of ELB353 in Healthy Men
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Placebo|DRUG: ELB353
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epoetin Alfa in Treating Chemotherapy-Related Anemia in Women With Stage I, Stage II, or Stage III Breast Cancer
Status: COMPLETED
Conditions: Anemia|Breast Cancer|Fatigue
Interventions: BIOLOGICAL: epoetin alfa|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: EQW, DAPA, EQW/DAPA, DAPA/MET ER and PHEN/TPM ER in Obese Women With PolycysticOvary Syndrome (PCOS)
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Obesity
Interventions: DRUG: Exenatide once weekly (EQW )|DRUG: Dapagliflozin (DAPA)|DRUG: EQW plus DAPA|DRUG: Dapagliflozin plus Glucophage (MET ER)|DRUG: Phentermine /Topiramate (PHEN/ TPM) ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Plane Block vs Intravenous Patient Controlled Analgesia
Status: COMPLETED
Conditions: Lumbar Disc Herniation
Interventions: DRUG: Erector spina plane block (ESP)|DRUG: Modified thoracolumbar interfacial plane block (MTI)|DRUG: Intravenous patient controlled analgesia (IV-PCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Immunomodulatory Therapy in Case of Psychiatric Disorders With Proven Dysimmunity.
Status: NOT_YET_RECRUITING
Conditions: Mental Disorder
Interventions: DRUG: immunomodulatory treatment by rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Pitt Center for Emergency Responder Wellness
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Depression|Anxiety|Alcohol Use Disorder
Interventions: BEHAVIORAL: Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Planning and Guided Dual Technique in Aesthetic Crown Lengthening
Status: COMPLETED
Conditions: Tooth Eruption Disorder
Interventions: PROCEDURE: Conventional aesthetic crown lengthening surgery|PROCEDURE: Guided dual aesthetic crown lengthening surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Whole vs. Nonfat Milk Consumption on Body Composition in Children
Status: RECRUITING
Conditions: Obesity|Diabetes|Cardiovascular Diseases
Interventions: BEHAVIORAL: Whole milk|BEHAVIORAL: Nonfat milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Selective Treatment According to Molecular Subtype of Prostate Cancer
Status: UNKNOWN
Conditions: Castration-resistant Prostate Cancer|Prostate Cancer Metastatic
Interventions: DRUG: Luminal type-1|DRUG: Luminal type-2|DRUG: Neuroendocrine type-1|DRUG: Neuroendocrine type-2|DRUG: Atypical type-1|DRUG: Atypical type-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: China Cimicifuga Trial of Climacteric Complaint Control
Status: UNKNOWN
Conditions: Climacteric Symptoms
Interventions: DRUG: an extract of Cimicifuga Foetida L.|DRUG: an extract of Cimicifuga Foetida L.|DRUG: placebo|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of Pneumococcal 7-Valent Conjugate Vaccine in Sickle Cell Disease Infants.
Status: TERMINATED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: Pneumo 23
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Reinnervated PAP Flap for Oral Cavity and Oropharyngeal Defect Reconstruction
Status: RECRUITING
Conditions: Oral Cavity Defect|Oropharynx Defect
Interventions: PROCEDURE: Surgical reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing a Pharmacist-Integrated Collaborative Model of Medication Treatment for Opioid Use Disorder
Status: RECRUITING
Conditions: Opioid Use Disorder|Substance Use Disorders
Interventions: OTHER: Pharmacist-integrated Medication Treatment for Opioid Use Disorder (PrIMO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of AP029 Mix in Patients With Impaired Carbohydrate Metabolism
Status: RECRUITING
Conditions: Diabetes in Adolescence|PreDiabetes
Interventions: DIETARY_SUPPLEMENT: AP029 mix|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Cannabidiol and Homotaurine in Patients With Mild Cognitive Impairment
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: DRUG: Cannabidiol Oil|DRUG: Homotaurine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Tissue (UC) Derived Mesenchymal Stem Cells (MSCs) Versus Placebo to Treat Acute Pulmonary Inflammation Due to COVID-19
Status: WITHDRAWN
Conditions: COVID-19|Acute Respiratory Distress Syndrome|Corona Virus Infection
Interventions: BIOLOGICAL: UCMSCs|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Hesperidin on Insulin Sensitivity
Status: WITHDRAWN
Conditions: Obesity|Insulin Resistance
Interventions: DRUG: Hesperidin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Pasireotide Long Acting Release (LAR) vs. Octreotide LAR in Patients With Active Acromegaly
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: Pasireotide|DRUG: Octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Mindfulness-Based Stress Reduction Program for Family or Caregivers of Children With Motor Disabilities
Status: NOT_YET_RECRUITING
Conditions: Stress, Psychological|Stress, Emotional|Stress
Interventions: BEHAVIORAL: Mindfulness-Based Stress reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Motivating Smokers at Outdoor Public Smoking Hotspots to Have Quit Attempt With Nicotine Replacement Therapy Sampling
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Nicotine replacement therapy (NRT) sampling|BEHAVIORAL: Smoking cessation counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Memantine Versus Bupropion on Smoking Relapse in Nicotine-Dependent Individuals - 3
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: DRUG: Memantine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adding Shock Wave Therapy to Kinesio Taping Improves Carpal Tunnel Syndrome in Physical Therapist Females.
Status: RECRUITING
Conditions: Physiopathology
Interventions: DEVICE: Shockwave|OTHER: Kinesio taping|OTHER: conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immune- and miRNA-response to Recombinant Interferon Beta in Healthy Volunteers and Patients With Relapsing Remitting Multiple Sclerosis
Status: UNKNOWN
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: DRUG: Rebif®|DRUG: Avonex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digestion of Biopolymer Based Lipid Emulsions
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Lipid emulsion|DIETARY_SUPPLEMENT: Lipid emulsion|DIETARY_SUPPLEMENT: Lipid emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: a Phase II Study in Primary Central Nervous System Lymphoma
Status: UNKNOWN
Conditions: Primary Central Nervous System Lymphoma
Interventions: DRUG: Methotrexate|DRUG: Methylprednisolone|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Denosumab in Combination With Chemotherapy as First-line Treatment of Metastatic Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Denosumab|DRUG: Zoledronic acid|DRUG: Placebo to Denosumab|DRUG: Standard Chemotherapy|DRUG: Placebo to Zoledronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Laparoscopic Spleen-Preserving No. 10 Lymph Node Dissection for Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Stomach Neoplasms
Interventions: PROCEDURE: Laparoscopic Spleen-Preserving No.10 Lymph Node Dissections|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Duration of Botox Using OLD Versus COLD for Treatment of Glabellar Lines
Status: UNKNOWN
Conditions: Glabellar Frown Lines
Interventions: DRUG: OnabotulinumtoxinA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Benefit for Treatment of Single Sided Deafness (SSD) Between Two Bone Conduction Prosthetic Devices; Osseointegrated Implant Versus Maxilla Anchored Removable Oral Appliance ("SoundBite")
Status: UNKNOWN
Conditions: Single Sided Deafness
Interventions: DEVICE: SoundBite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simulation-Free Hippocampal-Avoidance Whole Brain Radiotherapy Using Diagnostic MRI-Based and Cone Beam Computed Tomography-Guided On-Table Adaptive Planning in a Novel Ring Gantry Radiotherapy Device
Status: COMPLETED
Conditions: Intracranial Metastatic Disease From Any Solid Malignancy
Interventions: DEVICE: Ethos Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Breast Cancer, Sexuality and Black Cohosh
Status: UNKNOWN
Conditions: Sexuality
Interventions: BEHAVIORAL: WHOQOL questionnaire|BEHAVIORAL: FSFI questionnaire|BEHAVIORAL: kupperman scale|DRUG: Cimicifuga racemosa|DRUG: tamoxifen|DRUG: exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study of Qualaquin and Midazolam
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Midazolam Alone|DRUG: Qualaquin (quinine) alone steady state|DRUG: Midazolam and Qualaquin at steady state
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioavailability of Aronia Berry Polyphenols
Status: COMPLETED
Conditions: Gut Health|Metabolism|Polyphenols
Interventions: DIETARY_SUPPLEMENT: Whole Aronia Berry Powder Applesauce|DIETARY_SUPPLEMENT: Aronia Berry Extract Applesauce|DIETARY_SUPPLEMENT: Phospholipid-Polyphenol Applesauce|OTHER: Low-Polyphenol Control Applesauce
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transcranial Ultrasound Via Sonolucent Cranioplasty After Minimally Invasive Intracerebral Hemorrhage Evacuation
Status: RECRUITING
Conditions: Transcranial Ultrasound With Sonolucent Cranioplasty|TUSC
Interventions: DEVICE: ClearFit implant|PROCEDURE: transcranial ultrasonography through sonolucent cranioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: OraL Crushed and dIspersed Ticagrelor 180mg Compared to Whole Tablets of eQUal Dose in STEMI Patients unDergoing Primary PCI: a Pharmacokinetic/Pharmacodynamic Study (the LIQUID Study)
Status: COMPLETED
Conditions: ST Elevation Myocardial Infarction
Interventions: DRUG: Ticagrelor 180mg whole tablets|DRUG: Ticagrelor 180mg crushed and dispersed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TAPB vs QLBII for Kidney Transplantation Procedure
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Quadratus Lumborum Block type II|PROCEDURE: Transversus Abdominalis Plane Block|DRUG: Bupivacaine|DEVICE: Ultraplex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Age-related Normative Values for the Octopus 900 Perimeter
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Octopus 900 perimeter (Haag Streit AG, Koeniz, Switzerland)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Russian Non-Interventional Study on Compliance of Venous Thromboembolism (VTE)
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Hip|Arthroplasty, Replacement, Knee
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Abacavir Plus Indinavir Sulfate Plus Efavirenz in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Abacavir sulfate|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Short-term Clinical Effects of Anterior Extra-articular and Posterior Intra-articular Administration of Ultrasound-guided Steroid Injection in the Treatment of Adhesive Capsulitis.
Status: RECRUITING
Conditions: Adhesive Capsulitis of the Shoulder
Interventions: DRUG: A combination of 1 mL of triamcinolone acetonide (40 mg/mL) and 1 mL of prilocaine hydrochloride (2%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Helicobacter Pylori Eradication With Berberine Plus Amoxicillin Triple Therapy Versus Bismuth-containing Quadruple Therapy
Status: COMPLETED
Conditions: Dyspepsia|Chronic Gastritis|Gastric Cancer|Helicobacter Pylori Infection
Interventions: DRUG: Berberine|DRUG: Amoxicillin|DRUG: Rabeprazole|DRUG: Amoxicillin|DRUG: Clarithromycin|DRUG: Rabeprazole|DRUG: Bismuth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Hydrochloride, Clofarabine, and Busulfan Before Donor Stem Cell Transplant in Treating Patients With Refractory B-Cell or T-Cell Non-Hodgkin Lymphoma or Hodgkin Lymphoma
Status: COMPLETED
Conditions: Hematopoietic Cell Transplantation Recipient|Refractory B-Cell Non-Hodgkin Lymphoma|Refractory Hodgkin Lymphoma|Refractory T-Cell Non-Hodgkin Lymphoma
Interventions: PROCEDURE: Allogeneic Bone Marrow Transplantation|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|BIOLOGICAL: Anti-Thymocyte Globulin|DRUG: Busulfan|DRUG: Clofarabine|DRUG: Gemcitabine Hydrochloride|DRUG: Mycophenolate Mofetil|PROCEDURE: Peripheral Blood Stem Cell Transplantation|OTHER: Pharmacological Study|BIOLOGICAL: Rituximab|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptive Servo-Ventilation in "Real Life" Conditions : the OTRLASV Study
Status: COMPLETED
Conditions: Chronic Heart Failure and|Complex Sleep Apnea Syndrome|Obstructive Sleep Apnea Syndrome and|Idiopathic Central Sleep Apnea Syndrome|Idiopathic Induced Periodic Breathing|Central Sleep Apnea Syndrome
Interventions: DEVICE: Adaptive Servo-Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 24-hour Intraocular Pressure (IOP) Control With the Bimatoprost/Timolol Fixed Combination
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Drug: bimatoprost/timolol fixed combination AM|DRUG: Bimatoprost/timolol fixed combination dosed PM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Anti-tumor Activity, Safety and Pharmacology of IPH2101 in Patients With Smoldering Multiple Myeloma
Status: COMPLETED
Conditions: Smoldering Multiple Myeloma
Interventions: DRUG: IPH2101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study on the Safety and Efficacy of CAR-T Therapy for the TM4SF1- and EpCAM-positive Solid Tumors
Status: UNKNOWN
Conditions: Advanced Solid Tumor|Neoplasms
Interventions: BIOLOGICAL: TM4SF1- and EpCAM-positive chimeric antigen receptor T-cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capsule Endoscopy or Mesenteric Angiogram in Patients With Overt Gastrointestinal Bleeding (GIB) of Obscure Origin
Status: COMPLETED
Conditions: Gastrointestinal Hemorrhage
Interventions: PROCEDURE: capsule endoscopy|PROCEDURE: Mesenteric Angiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Exploration of Relationships Between Sleep, Gut Health and Cognition
Status: UNKNOWN
Conditions: Insomnia|Sleep Disturbance
Interventions: DIETARY_SUPPLEMENT: Saffr'Inside; 30mg|BEHAVIORAL: Enhanced Sleep Education|DIETARY_SUPPLEMENT: Placebo food supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Phase I/II Evaluation of Temozolomide and ZARNESTRA (R115777) for Recurrent and Progressive Glioblastoma Multiforme
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Temozolomide|DRUG: R115777
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study for the Effectiveness of Intensive Therapy Aiming at a Remission of Diabetic Nephropathy
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Diabetic Nephropathy
Interventions: OTHER: Intensive multifactorial therapy|OTHER: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vsling™ III: Clinical Evaluation of the Vsling™ Device for Ventricular Repair in Patients With Heart Failure
Status: NOT_YET_RECRUITING
Conditions: HFrEF - Heart Failure With Reduced Ejection Fraction
Interventions: DEVICE: Vsling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Oseltamivir Versus Paracetamol for Influenza-like Illness During the Influenza Season
Status: UNKNOWN
Conditions: Influenza
Interventions: DRUG: Oseltamivir|DRUG: Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Phase III Trial of Adjuvant Chemotherapy or Chemoradiotherapy in Resectable Gastric Cancer (CRITICS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: cisplatin+capecitabine|RADIATION: radiotherapy|DRUG: epirubicin+cisplatin+capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Combination Therapy of Nanofat Grafting and PRP Compared With Microfat Grafting and PRP Synergy in Treating Striae Distensae
Status: UNKNOWN
Conditions: Treatments of Striae Distensae
Interventions: PROCEDURE: Nanofat grafting|PROCEDURE: Microfat grafting|PROCEDURE: Platelet-rich plasma (PRP) Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bacterial Reduction of Rotary Versus Manual Filing System Using Different Irrigants in Primary Molars
Status: COMPLETED
Conditions: Necrotic Pulp
Interventions: PROCEDURE: manual saline IA|PROCEDURE: manual neem IB|PROCEDURE: manual sodium hypochlorite IC|PROCEDURE: rotary saline IIA|PROCEDURE: rotary neem IIB|PROCEDURE: rotary sodoium hypochlorite IIC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SWiss Multicenter Intracoronary Stem Cells Study in Acute Myocardial Infarction (SWISS-AMI)
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: PROCEDURE: intracoronary bone marrow cells infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Effectiveness of Micronutrients as Palliative Care Therapy in Patients With Congestive Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure|Ischemic Cardiomyopathy
Interventions: DRUG: Micronutrients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pre-mapping Networks for Brain Stimulation 2
Status: COMPLETED
Conditions: Depressive Episode|Major Depressive Disorder
Interventions: DEVICE: Neuronavigated aiTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Insulin Resistance To Treat Non-Alcoholic Fatty Liver Disease: A Pilot Study
Status: WITHDRAWN
Conditions: Non-alcoholic Fatty Liver Disease (NAFLD)
Interventions: DRUG: Metformin|BEHAVIORAL: Lifestyle modifications|DEVICE: Fibroscan device (Echosens)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Metformin on Decrement in Levothyroxin Dose Required for Thyroid Stimulating Hormone (TSH) Suppression in Patients With Differentiated Thyroid Cancer
Status: COMPLETED
Conditions: Malignant Neoplasm of Thyroid Stage I|Malignant Neoplasm of Thyroid Stage II
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Video Based Education Versus Music Therapy on Anxiety, Experience, and Co-operation Among Patients Undergoing Magnetic Resonance Imaging in Radiology Department at ILBS, New Delhi.
Status: COMPLETED
Conditions: Effectiveness of Video Based Education Versus Music Therapy on Anxiety, Experience, and Co-operation Among Patients Undergoing Magnetic Resonance Imaging
Interventions: BEHAVIORAL: Video Based Education, Music Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Use of Electrical Stimulation for Determination of Epidural Catheter Placement
Status: NOT_YET_RECRUITING
Conditions: Obstetric Pain|Anesthesia, Local
Interventions: DIAGNOSTIC_TEST: Electrical Epidural Stimulation Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Whey Protein and Collagen Supplementation
Status: COMPLETED
Conditions: Exercise|Nutrition Therapy|Resistance Training|Muscle Strength|Hypertrophy
Interventions: DIETARY_SUPPLEMENT: Whey protein supplementation|DIETARY_SUPPLEMENT: Collagen supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: HOPE-2 Study (Heart Outcomes Prevention Evaluation-2 Study)
Status: UNKNOWN
Conditions: Cardiovascular Disease|Myocardial Infarction|Stroke|Cancer
Interventions: DRUG: Folic acid, vitamin B6 and B12 or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effect of Different Doses of AMG 706 on the Gallbladder in Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: AMG 706|DRUG: AMG 706|DRUG: AMG 706
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Radiotherapy Combined With Raltitrexed and Irinotecan in Metastatic or Locally Recurrent Colorectal Cancer
Status: UNKNOWN
Conditions: Recurrent Colorectal Cancer
Interventions: COMBINATION_PRODUCT: Radiotherapy Combined With Raltitrexed and Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adolescents With COVID-19/MIS-C at HCFMUSP
Status: UNKNOWN
Conditions: Covid19|Corona Virus Infection|SARS (Severe Acute Respiratory Syndrome)|SARS-CoV Infection
Interventions: BEHAVIORAL: Home-based exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Study of Navelbine in Patients With HER2 Positive Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Navelbine|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-Coated Balloon in Native Chronic Total Occlusion Percutaneous Coronary Intervention
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Total Occlusion of Coronary Artery
Interventions: DEVICE: Paclitaxel Drug-coated balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Optimal-Massive Intervention in Older Patients With Dysphagia
Status: UNKNOWN
Conditions: Swallowing Disorder|Oropharyngeal Dysphagia|Respiratory Infection|Malnutrition|Dehydration|Oral Disease
Interventions: OTHER: Optimal-Massive Intervention|OTHER: Control (standard clinical practice)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Error-enhanced Learning & Recovery in 2 & 3 Dimensions
Status: RECRUITING
Conditions: Stroke|Cerebral Vascular Accident (CVA)/Stroke
Interventions: OTHER: Error Fields|OTHER: No Error Fields
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Urolithin A Supplementation to Boost Immune Health
Status: ACTIVE_NOT_RECRUITING
Conditions: Aging
Interventions: DIETARY_SUPPLEMENT: Softgel containing placebo|DIETARY_SUPPLEMENT: Softgel containing 250mg of Urolithin A (Mitopure)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Supra-renal Fixation of EVAR on Hemodynamics of Renal Arteries
Status: UNKNOWN
Conditions: Aortic Aneurysm, Abdominal|Endovascular Procedures|Renal Artery Stenosis
Interventions: DEVICE: endovascular aneurysm repair (EVAR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of LH Supplementation on the Endometrial Gene Expression Profile in Poor Ovarian Responders
Status: WITHDRAWN
Conditions: Poor Response to Ovulation Induction
Interventions: DRUG: Lutropin alfa|DRUG: Follitropin alfa|DIAGNOSTIC_TEST: Endometrial biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Vitality, Independence, and Vigor in Elders Study I Clinical Trial
Status: COMPLETED
Conditions: Functionally Limited|Sedentary
Interventions: OTHER: Successful Aging Program|OTHER: Exercise-Nutrition Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study of VRd-based Regimen Combined With CART-ASCT-CART2 Treatment in NDMM Patients With P53 Abnormalities
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: anti-BCMA CAR-T|DRUG: VRD-based Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Oral Vitamin D Supplementation in Adolescents and Young Adults.
Status: COMPLETED
Conditions: Overweight and Obesity|Overweight Adolescents|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: 1000 IU D vitamin|DIETARY_SUPPLEMENT: 200 IU D vitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Propranolol in the Treatment of Tardive Dyskinesia
Status: WITHDRAWN
Conditions: Tardive Dyskinesia
Interventions: DRUG: Propranolol Hydrochloride|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Efficacy of Triple Combination in Drug-naïve Korean Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Initial triple combination|DRUG: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hormonal and Metabolic Aspects of Endoscopic Sleeve Gastroplasty
Status: WITHDRAWN
Conditions: Endoscopic Sleeve Gastroplasty|Laparoscopic Sleeve Gastrectomy|Gut Hormones|Glucose Metabolism Disorders
Interventions: PROCEDURE: Endoscopic sleeve gastroplasty|PROCEDURE: Laparoscopic sleeve gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectivity of Slackline-Training in Physiotherapy
Status: COMPLETED
Conditions: Healthy Volunteers|Persons With no Known Significant Health Problems
Interventions: DEVICE: Slackline|DEVICE: Wobbling Board|DEVICE: Pre-training|DEVICE: Fix visual anchor|DEVICE: Moving visual anchor|DEVICE: Post-training|DEVICE: Slackline vs. standing-on-1-leg vs. control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PEAK PlasmaBlade 4.0 Versus Traditional Electrosurgery in Total Knee Replacement.
Status: TERMINATED
Conditions: Degenerative Joint Disease|Osteoarthritis
Interventions: DEVICE: PEAK PlasmaBlade 4.0|DEVICE: Traditional Electrosurgery with scalpel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Opt-In Versus Opt-Out for Colorectal Cancer Screening Outreach
Status: COMPLETED
Conditions: Cancer of the Colon
Interventions: BEHAVIORAL: Opt-In Outreach|BEHAVIORAL: Opt-Out Outreach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Computerized Decision Support to Prevent Stroke in Atrial Fibrillation
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Stroke
Interventions: BEHAVIORAL: Alert-based computerized decision support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics of Omadacycline in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Omadacycline Injection [Nuzyra]|DRUG: Omadacycline Oral Tablet [Nuzyra]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate Safety & Efficacy of FLX-787-ODT to Treat Fasciculations in Tongue and Appendicular Muscle in Adult Subjects With ALS
Status: TERMINATED
Conditions: Amyotrophic Lateral Sclerosis|Fasciculation
Interventions: DRUG: FLX-787-ODT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FST-100 Ophthalmic Suspension in Acute Adenoviral Conjunctivitis
Status: TERMINATED
Conditions: Acute Adenoviral Conjunctivitis
Interventions: DRUG: FST-100 Ophthalmic Suspension|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of SID1903 (FDC of Dapagliflozin and Sitagliptin) in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: SID1903|DRUG: SID1903-R1/SID1903-R2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Synbiotic Supplementation on the Prevention of Mucositis in Cancer Patients Undergoing Chemotherapy
Status: RECRUITING
Conditions: Colo-rectal Cancer
Interventions: DIETARY_SUPPLEMENT: Symbiotic|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Botulinum Toxin Injections in Patients With Hereditary Spastic Paraplegia
Status: COMPLETED
Conditions: Hereditary Spastic Paraplegia
Interventions: OTHER: Botulinum Toxin Injections|OTHER: Placebo Injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N-3 Polyunsaturated Fatty Acids Enriched Chicken Meet and Cardiovascular Function
Status: RECRUITING
Conditions: n-3 Polyunsaturated Fatty Acids
Interventions: DIETARY_SUPPLEMENT: N-3 PUFAs Chicken Meet|DIETARY_SUPPLEMENT: Regular Chicken Meet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial of Immunobridging and Lot-to-lot Consistency of COVID-19 Vaccine (Ad5-nCoV) in Different Age Groups.
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) 0.5ml|BIOLOGICAL: Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) 0.3ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Radiotherapy Assessments During Intervention ANd Treatment (RADIANT)
Status: COMPLETED
Conditions: Radiation Therapy|Cancer|Cancer of Anus|Cancer of Bladder|Cancer of Cervix|Cancer of Colon|Cancer of Rectum|Cancer of Esophagus|Cancer of Gallbladder|Cancer of Liver|Cancer of Ovary|Cancer of Pancreas|Cancer of Prostate|Cancer of Kidney and Renal Pelvis|Cancer of Stomach|Cancer of Testis|Cancer of Uterus|Cancer of Uterus and Cervix|Cancer of Kidney
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 3D Versus 4K Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Cholecystitis|Gallstones
Interventions: PROCEDURE: 3D laparoscopy|PROCEDURE: 4K laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Alpha Particle Radiotherapy for Metastatic Uveal Melanoma
Status: RECRUITING
Conditions: Uveal Melanoma|Metastatic
Interventions: DRUG: 4.7 microCi 225Ac-MTI-201|DRUG: 9.5 microCi of 225Ac-MTI-201|DRUG: 19 microCi of 225Ac-MTI-201|DRUG: 38 microCi of 225Ac-MTI-201|DRUG: 76 microCi of 225Ac-MTI-201|DRUG: 152 microCi of 225Ac-MTI-201|DRUG: 254 microCi of 225Ac-MTI-201|DRUG: 424 microCi of 225Ac-MTI-201|DRUG: 564 microCi of 225Ac-MTI-201|DRUG: 750 microCi of 225Ac-MTI-201|DRUG: 998 microCi of 225Ac-MTI-201|DRUG: 1327 microCi of 225Ac-MTI-201
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tamoxifen Compared With LY353381 in Treating Women With Newly Diagnosed Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: arzoxifene hydrochloride|DRUG: tamoxifen citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Health Economic Assessment of Lower Extremity Diabetic (HEALED) Ulcers With PriMatrix
Status: TERMINATED
Conditions: Foot Ulcer, Diabetic
Interventions: DEVICE: PriMatrix Moist Wound Therapy|OTHER: Standard of Care Moist Wound Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Suvorexant and Cocaine
Status: COMPLETED
Conditions: Cocaine Use Disorder
Interventions: DRUG: Suvorexant|DRUG: Cocaine|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: HFNC vs. NIV in Acute COPD Exacerbations
Status: COMPLETED
Conditions: COPD Exacerbations|Acute Hypercapnic Respiratory Failure|Respiratory Failure
Interventions: DEVICE: NIV|DEVICE: HFNC-30|DEVICE: HFNC-50
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suprachoroidal CLS-TA With Intravitreal Aflibercept Versus Aflibercept Alone in Subject With Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: IVT aflibercept|DRUG: Sham SC|DRUG: SC CLS-TA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Non-inferiority, Multicenter and Randomized, Multiple-Dose Study About a Treatment to Hypolactasia
Status: COMPLETED
Conditions: Lactose Intolerance
Interventions: DRUG: Lactase Oral Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of PF-06410293 And Adalimumab In Healthy Subjects (REFLECTIONS B538-01)
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: PF-06410293|BIOLOGICAL: Humira (adalimumab-EU)|BIOLOGICAL: Humira (adalimumab-US)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: "Feasibility and Safety of the Calcium Alginate Hydrogel Sealant for the Treatment of Cryptoglandular Fistula-in-ano: Phase I/IIa Clinical Trial"
Status: COMPLETED
Conditions: Anal Fistula
Interventions: PROCEDURE: Calcium alginate hydrogel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Development and Evaluation of a Quantitative HP MRI for Clinical Prostate Cancer Exam
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Adenocarcinoma
Interventions: OTHER: Hyperpolarized Carbon C 13 Pyruvate|PROCEDURE: Magnetic Resonance Spectroscopic Imaging|PROCEDURE: Surgical Procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Naltrexone for At-Risk and Problem Drinking in Smoking Cessation Treatment
Status: COMPLETED
Conditions: Hazardous Drinking|Cigarette Smoking
Interventions: DRUG: Naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Two Different Physical Therapy Protocols After an Endodontic Intervention
Status: COMPLETED
Conditions: Root Canal Therapy|Endodontically Treated Teeth
Interventions: OTHER: Manual Therapy + Dry Needling|OTHER: Manual Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of RSV Monoclonal Antibody RSM01 in Healthy Adults
Status: COMPLETED
Conditions: RSV Infection
Interventions: DRUG: RSM01|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Saxagliptin (BMS-477118) in Combination With Metformin IR or Metformin XR in Pediatric Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Alone
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo matching with Saxagliptin|DRUG: Metformin IR|DRUG: Metformin XR|DRUG: Saxagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety, Tolerability, and Biological Activity of LAM-002A in C9ORF72-Associated Amyotrophic Lateral Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis|ALS
Interventions: DRUG: LAM-002A|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Anesthetic Methods on Gastrointestinal Motility
Status: COMPLETED
Conditions: Anesthesia|Total Intravenous Anesthesia
Interventions: DRUG: Desflurane|DRUG: Remifentanil infusion|OTHER: Fresh gas|DRUG: Propofol infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER