pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: TBS,TMS, Suicidal Ideation, Magnetic Resonance Imaging, Dorsolateral Prefrontal Cortex, Ventrolateral Prefrontal Cortex
Status: RECRUITING
Conditions: Late Life Depression
Interventions: DEVICE: Transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Advisa MRI Clinical Study
Status: COMPLETED
Conditions: Magnetic Resonance Imaging|Cardiac Pacemaker, Artificial
Interventions: DEVICE: Medtronic Advisa MRI Implantable Pulse Generator (IPG)|DEVICE: Medtronic CapSureFix MRI™ active fixation MRI lead
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Efficacy Study of Fluocinolone Acetonide Inserts in Patients With Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Fluocinolone Acetonide|DRUG: Fluocinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abdominal Obesity and Cardiovascular Risk Factors in Women Who Survived Cancer or a Related Illness Following Total Body Irradiation and Stem Cell Transplant
Status: COMPLETED
Conditions: Leukemia|Hodgkin's Lymphoma|Non-Hodgkin's Lymphoma|Myelodysplastic Syndrome
Interventions: OTHER: Questionnaires, Laboratory tests, Abdominal MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Proper Duration of Suppressive Antibiotic Therapy After Debridement, Antibiotics, and Implant Retention
Status: RECRUITING
Conditions: Periprosthetic Joint Infection|Antibiotic Suppression
Interventions: DRUG: 6 months of SAT|DRUG: 12 months of SAT|DRUG: Indefinite SAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified CV Regimen in Optic Pathway Glioma
Status: RECRUITING
Conditions: Optic Glioma|Pediatric Brain Tumor, Optic Nerve Glioma
Interventions: DRUG: Carboplatin|DRUG: Vincristine|DRUG: Recombinant human endostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study of BMS-477118 in Combination With Metformin in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: Saxagliptin|DRUG: Saxagliptin|DRUG: Metformin|DRUG: Placebo|DRUG: pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Egyptian Hepatitis C Genotype 4 Infected Children (and Adolescents) With Combined Sofosbuvir & Daclatasvir
Status: COMPLETED
Conditions: Hepatitis C Genotype 4
Interventions: DRUG: Combined Therapy SOF and DCV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of HuCNS-SC in Subjects With Neuronal Ceroid Lipofuscinosis
Status: WITHDRAWN
Conditions: Neuronal Ceroid Lipofuscinosis
Interventions: BIOLOGICAL: HuCNS-SC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ASAP - Assisted Immediate Augmented Post-/Long-COVID Plan for Patients Infected With COVID-19
Status: COMPLETED
Conditions: Long-COVID|Post-COVID|Psychosomatic Disorder|Psychological Distress|Psychological Disease|Psychological Disorder|Psychological Impairment|Psychological Adjustment|Physiological Disease|Physiological Disorder|Physiological Impairment|Physiological Adjustment|Healthy Lifestyle
Interventions: DIAGNOSTIC_TEST: Psychological and Physiological Assessments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Exercise Training and Detraining on Frailty and Fall Risk in Patients With Chronic Heart Failure
Status: RECRUITING
Conditions: Chronic Heart Failure
Interventions: OTHER: Exercise Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Temperature Control Liner Materials on Long-Term Outcomes of Prothesis Use
Status: TERMINATED
Conditions: Artificial Limbs|Skin Diseases
Interventions: DEVICE: Prosthesis suspension liner
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between 3-L and 4-L Polyethylene Glycol in Bowel Preparation
Status: UNKNOWN
Conditions: Bowel Preparation Scale|Adenoma Detection Rate
Interventions: DRUG: 4L Polyethylene Glycol|DRUG: 3L Polyethylene Glycol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Sub-Acute Stroke Rehabilitation With AMES
Status: COMPLETED
Conditions: Cerebrovascular Stroke
Interventions: DEVICE: AMES device (test)|DEVICE: AMES device (sham)|DEVICE: AMES device (crossover)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NdYag Laser for Acne Keloidalis Nuchae
Status: UNKNOWN
Conditions: Acne Keloidalis Nuchae|NdYag Laser|AKN|Acne Keloidalis|AK|Dermatitis Papillaris Capillitii|Folliculitis Keloidalis Nuchae|Sycosis Nuchae|Acne Keloid|Keloidal Folliculitis|Lichen Keloidalis Nuchae|Folliculitis Nuchae Scleroticans|Sycosis Framboesiformis
Interventions: DEVICE: NdYag Laser(hair removal laser) plus topical corticosteroid|DRUG: Topical corticosteroid alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stromal Cells in Living Donor Kidney Transplantation
Status: UNKNOWN
Conditions: Renal Transplantation|Mesenchymal Stem Cells
Interventions: BIOLOGICAL: Mesenchymal Stromal Stem Cells (MSCs) Infusion|OTHER: Normal Saline (Placebo) Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study of Apatinib Combined With Oral Vinorelbine in Metastatic HER2 Negative Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Apatinib|DRUG: Oral Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Kendall Exercise Versus Gong's Mobilization in Text Neck Syndrome. A Pilot Study
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Kendall exercise|OTHER: Gong's mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Utility of Camostat Mesylate in Patients With COVID-19 Associated Coagulopathy (CAC) and Cardiovascular Complications
Status: WITHDRAWN
Conditions: Coagulopathy|Cardiovascular Complication|COVID-19
Interventions: DRUG: Camostat Mesylate|DRUG: Microcrystalline Cellulose, NF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dermal and Gynecological Acceptability (Irritability and Sensitization in the Genital Mucosa) of an Investigational Product and Evaluation of Moisture Efficacy by TEWL and Perceived Efficacy.
Status: UNKNOWN
Conditions: Female Dry Genital Mucosa
Interventions: OTHER: Intimate Lubricant Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Metagenomic Analysis of Gut Microbiome in Korean Patients With Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: PROCEDURE: Colonoscopy biopsy|OTHER: stool collection|PROCEDURE: colonoscopy biopsy|OTHER: stool collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetic of Doripenem and Piperacillin/Tazobactam in More Than 120 kg Critically Ill Patients
Status: COMPLETED
Conditions: Septic Shock
Interventions: DRUG: Doripenem or Piperacillin/Tazobactam|DRUG: Doripenem or Piperacillin/Tazobactam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Intrabony Periodontal Defects With Enamel Matrix Derivatives and Autogenous Bone Graft
Status: COMPLETED
Conditions: Periodontal Bone Loss|Chronic Periodontitis
Interventions: PROCEDURE: Open Flap Debridement|BIOLOGICAL: EmdogainⓇ(Enamel Matrix Derivative)|BIOLOGICAL: EmdogainⓇEnamel Matrix Derivative+Autogenous Bone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Development and Testing of a Scaling Strategy for a Community-Based Primary Care Antimicrobial Stewardship Program
Status: UNKNOWN
Conditions: Acute Rhinosinusitis|Sore Throat|Acute Cystitis|Acute Bronchitis
Interventions: BEHAVIORAL: Enhanced CB-ASP|BEHAVIORAL: Standard CB-ASP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Desmopressin on Platelet Function in CKD Patients on Antiplatelet Drug
Status: COMPLETED
Conditions: Bleeding|Tachycardia|Dyspnea
Interventions: DRUG: Desmopressin administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Empagliflozin on Renal Outcomes in Post Severe Acute Kidney Injury Survivors
Status: RECRUITING
Conditions: Empagliflozin in Post AKI Stage 2-3
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Heart Rate Changes in Schizophrenic and Bipolar Patients Under the Medication of Aripiprazole and Quetiapine
Status: UNKNOWN
Conditions: Schizophrenia|Bipolar
Interventions: DRUG: Aripiprazole; Quetiapine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Chronic Hepatitis C Infection in Treatment Experienced Adults
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection
Interventions: DRUG: ABT-450/r/ABT-267, ABT-333|DRUG: Ribavirin|DRUG: Placebo for ABT-450/r/ABT-267|DRUG: Placebo for ABT-333|DRUG: Placebo for ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Plasmapheresis: a Multi-modal Approach
Status: COMPLETED
Conditions: Plasmapheresis|Haematology|Sport Performance|Body Composition|Inflammation|Immunology|Adverse Events
Interventions: DEVICE: Plasmapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Optimum Insufflation Capacity in NMD
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy|Spinal Muscular Atrophy|Chronic Respiratory Insufficiency
Interventions: PROCEDURE: IPPB|PROCEDURE: LIAM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study to Test the Feasibility of a Hybrid Preoperative Physical Therapy Intervention for Patients Undergoing Total Joint Arthroplasty
Status: COMPLETED
Conditions: Total Joint Arthroplasty
Interventions: OTHER: Hybrid Peroperative PT|OTHER: Standard Clinical Practice PT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety/Efficacy Trial of Killed Leishmania Vaccine in Volunteers With no Response to Leishmanin
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Alum-ALM + BCG|BIOLOGICAL: Alum-ALM + BCG|BIOLOGICAL: Alum-ALM + BCG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: BRAVO Study: Laquinimod Double-blind Placebo-controlled Study in Participants With Relapsing-Remitting Multiple Sclerosis (RRMS) With a Rater Blinded Reference Arm of Interferon β-1a (Avonex®)
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Laquinimod|DRUG: Placebo|DRUG: Avonex®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Feasibility of Delivering an Education Program to Patients With an Acute Exacerbation of COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease With (Acute) Exacerbation
Interventions: OTHER: Introductory Disease Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Once-a-day Regimen With Everolimus, Low Dose Cyclosporine and Steroids in Comparison With Steroid Withdrawal or Twice a Day Regimen With Everolimus, Low Dose Cyclosporine and Steroids.
Status: COMPLETED
Conditions: de Novo Kidney Transplant Recipients|Renal Transplantation
Interventions: DRUG: everolimus|DRUG: cyclosporine|DRUG: Prednison (continuous steroids)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability and Pharmacokinetics of Single Rising Oral Doses of BI 1015550 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1015550|DRUG: BI 1015550|DRUG: BI 1015550|DRUG: BI 1015550|DRUG: BI 1015550|DRUG: Placebo|DRUG: BI 101550|DRUG: BI 1015550|DRUG: BI 1015550|DRUG: BI 1015550
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: The Use of Heliox Via Nasal CPAP to Prevent Early CPAP Failure in Premature Infants: A Feasibility Study
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Newborn
Interventions: OTHER: Heliox gas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of Adipose Derived Mesenchymal Stem Cells for Treatment of Pulmonary Arterial Hypertension
Status: UNKNOWN
Conditions: Pulmonary Hypertension
Interventions: BIOLOGICAL: adipose derived mesenchymal stem cells|DRUG: Conventional drug therapy（expectorant，bronchodilator）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Valproate on Angiogenesis and Histone Deacetylation in Bladder Cancer
Status: COMPLETED
Conditions: Hematuria|Bladder Cancer
Interventions: DRUG: Valproic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Velcade, Thalidomide, Dexamethasone and Panobinostat Treatment and Panobinostat Maintenance in Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Velcade|DRUG: Thalidomide|DRUG: Dexamethasone|DRUG: Panobinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of an Inhaled Glucocorticoid-long-acting Beta Adrenergic Agonist on Endothelial Function in COPD
Status: WITHDRAWN
Conditions: COPD
Interventions: DRUG: Placebo|DRUG: Fluticasone /salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Study to Evaluate the Long-term Safety of Inclacumab Administered to Participants With Sickle Cell Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Sickle Cell Disease|Vaso-occlusive Crisis|Vaso-occlusive Pain Episode in Sickle Cell Disease
Interventions: DRUG: Inclacumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Tetravalent Dengue Vaccine Candidate (TDV) in Flavivirus-Naïve and Dengue-Immune Adults
Status: COMPLETED
Conditions: Dengue Fever
Interventions: BIOLOGICAL: TDV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study Investigating the Pharmacokinetic Properties of the Drug Lu AF35700 in Subjects With Liver Impairment and in Healthy Subjects
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Lu AF35700
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of MD1003 in Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: ALS|Amyotrophic Lateral Sclerosis|Motor Neuron Disease
Interventions: DRUG: MD1003|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Group Cognitive Processing Therapy for Combat-related Posttraumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Group Cognitive Processing Therapy-Cognitive Only|BEHAVIORAL: Group Present Centered Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine in Cardiovascular Disease in Patients With Chronic Kidney Disease: A Proof of Concept Study
Status: TERMINATED
Conditions: Kidney Failure, Chronic|Cardiovascular Disease|Arteriosclerosis
Interventions: DRUG: Hydroxychloroquine|OTHER: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Safety Study of IPI-504 in Relapsed/Refractory Stage IIIb, or Stage IV Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: IPI-504
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trigger Point Injections for Post-Mastectomy Pain Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Post-mastectomy Pain Syndrome|Myofascial Pain Syndrome|Trigger Point Pain, Myofascial|Breast Cancer
Interventions: PROCEDURE: Trigger point injection|PROCEDURE: Subcutaneous saline injection|OTHER: Comprehensive Rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: etoposide|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Study Comparing SynPath to Standard of Care in Treatment of Chronic Diabetic Foot Ulcers
Status: TERMINATED
Conditions: Diabetic Foot|Chronic Foot Ulcer|Wound Healing|Foot Ulcer
Interventions: DEVICE: SynPath Acellular Dermal Matrix plus Off-loading Device|DEVICE: Wound Dressing composed of 90% collagen and 10% Alginate plus Off-loading Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sirolimus for Graves' Orbitopathy (GO)
Status: NOT_YET_RECRUITING
Conditions: Graves Ophthalmopathy
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and Vinorelbine Plus Filgrastim in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: docetaxel|DRUG: vinorelbine tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of Paliperidone Palmitate 3 Month Formulation for the Treatment of Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: PP3M 175 mg eq.|DRUG: PP3M 263 mg eq.|DRUG: PP3M 350 mg eq.|DRUG: PP3M 525 mg eq.|DRUG: Placebo (20% Intralipid emulsion)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of an Physical Exercise Program on Older People of 75 Years Old and More, Hospitalized in Geriatric Short Stay
Status: RECRUITING
Conditions: Physical Activity|Aged
Interventions: PROCEDURE: "Control" strategy|PROCEDURE: "Intervention" strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of KYN-5356 in Healthy Subjects Aged 18 to 55 Years
Status: RECRUITING
Conditions: Cognitive Dysfunction|Schizophrenia
Interventions: DRUG: KYN-5356|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endothelin Receptor Antagonism in Proteinuric Nephropathy
Status: COMPLETED
Conditions: Chronic Kidney Disease|Proteinuria
Interventions: DRUG: BQ-123 (selective endothelin A receptor antagonist)|DRUG: 0.9 % saline|DRUG: Nifedipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Radiomics Signature of Hepatic Venous Pressure Gradient (rHVPG) With CT Angiography (CHESS1701)
Status: COMPLETED
Conditions: Hypertension, Portal
Interventions: PROCEDURE: HVPG measurement|PROCEDURE: CTA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Observational Study of People Living With HIV Treated With CD19-directed CAR T Cell
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia|Leukemia, Lymphoblastic|Lymphoma, Large B-Cell, Diffuse|Follicular Lymphoma|Lymphoma, B-Cell|Lymphoma, Follicular|Lymphoma, Non-Hodgkin|HIV Infections|HIV Associated Lymphoma|HIV Disease; Lymphoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Low-dose Sirolimus to Kaposiform Hemangioendothelioma
Status: COMPLETED
Conditions: Hemangioma|Kaposiform Hemangioendothelioma
Interventions: DRUG: Sirolimus(0.8mg/m2)|DRUG: Sirolimus(0.7mg/m2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation and Cohort Expansion of Safety and Tolerability Study of Intratumoral rAd.CD40L (ISF35) in Combination of Systemic Pembrolizumab in Patients With Refractory Metastatic Melanoma
Status: WITHDRAWN
Conditions: Melanoma
Interventions: DRUG: rAd.CD40L|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patterned Functional Electrical Stimulation (FES) Ergometry of Arm and Shoulder in Individuals With Spinal Cord Injury
Status: TERMINATED
Conditions: Spinal Cord Injury
Interventions: DEVICE: Non-FES Upper Extremity Exercise|DEVICE: RT300-SLSA, from Restorative Therapies, Inc.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Leuprolide Acetate Depot in Children With Central Precocious Puberty
Status: RECRUITING
Conditions: Central Precocious Puberty
Interventions: DRUG: Leuprorelin Acetate Depot 3M
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ischaemic Preconditioning and Upper Body Exercise Performance in Persons With Spinal Cord Injury
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries
Interventions: OTHER: Ischaemic Preconditioning|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Efficacy and Safety of Ocrelizumab in Patients With Relapsing-Remitting Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Placebo|DRUG: Ocrelizumab|DRUG: Avonex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combinatorial Nutritional Supplementation on Immune Function in Healthy Older Adults
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Redoxon VI|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Antibiotic Prophylaxis Before Shock Wave Lithotripsy
Status: RECRUITING
Conditions: Ureteral Stones|Ureteral Calculi|Nephrolithiasis
Interventions: DRUG: Ciprofloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized, Double-Blind, Placebo-Controlled, Safety and Tolerability Study of ITI-214 in Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure, Systolic
Interventions: DRUG: ITI-214|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Vitamin C to Reduce Persistent Pain After Total Knee Arthroplasty
Status: RECRUITING
Conditions: Chronic Pain|Knee Pain Chronic|Post Operative Pain
Interventions: DRUG: Vitamin C|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HMPL-523 in Adult Subjects With Immune Thrombocytopenia (ITP)
Status: RECRUITING
Conditions: Immune Thrombocytopenia|Blood Platelet Disorder|Hematologic Diseases|Purpura, Thrombocytopenic|Purpura|Blood Coagulation Disorder|Thrombotic Microangiopathies|Hemorrhagic Disorders|Autoimmune Diseases|Immune System Diseases|Hemorrhage|Pathologic Processes|Skin Manifestations|Thrombocytopenia|Purpura, Thrombocytopenic, Idiopathic|Primary Immune Thrombocytopenia|ITP - Immune Thrombocytopenia
Interventions: DRUG: HMPL-523
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BL22 Immunotoxin in Treating Patients With Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia
Status: WITHDRAWN
Conditions: Leukemia|Lymphoma
Interventions: DRUG: BL22 immunotoxin|PROCEDURE: antibody therapy|PROCEDURE: biological response modifier therapy|PROCEDURE: immunotoxin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Trial Evaluating the Safety and Effectiveness of NUBAC™ Disc Arthroplasty
Status: COMPLETED
Conditions: Degenerative Disc Disease
Interventions: DEVICE: NuBac|DEVICE: Prodisc-L
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Blood Loss During Cesarean Section. Comparing Two Techniques of Blunt Expansion of Uterine Incision: Transversal vs. Cephalad-caudad,
Status: COMPLETED
Conditions: Blunt Expansion of the Uterine Incision
Interventions: PROCEDURE: Cephalad-caudad expansion|PROCEDURE: Transversal expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Low Dose Iron-containing Micronutrient Powders on Iron Status and Morbidity of Young Children in Ethiopia
Status: COMPLETED
Conditions: Nutritional Anemia|Infant Morbidity
Interventions: DIETARY_SUPPLEMENT: Micronutrient Powder (MNP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: NovoTTF-200A + Pembrolizumab In Melanoma Brain Metastasis
Status: NOT_YET_RECRUITING
Conditions: Metastatic Melanoma|Melanoma Brain Metastasis
Interventions: DEVICE: NovoTTF-200A|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Applying Moziak Device Compared to Standard Manual Compression on Arterio-Venous Fistula Puncture Sites Haemostasis
Status: COMPLETED
Conditions: Post Dialysis Arterio-Venous Fistula Puncture Sites
Interventions: DEVICE: Moziak Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Study of Intravenous Labetalol Versus Intravenous Nitroglycerin Versus Sublingual Nifedipine
Status: NOT_YET_RECRUITING
Conditions: Severe Preeclampsia
Interventions: DRUG: Labetalol|DRUG: Nitroglycerine|DRUG: Nifedipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate DRP-104 in Adults With Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumor|Non Small Cell Lung Cancer Metastatic
Interventions: DRUG: DRP-104|BIOLOGICAL: atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Outcomes After EUS-guided Ablation for Cystic Tumors of the Pancreas
Status: UNKNOWN
Conditions: Cystic Tumors of the Pancreas
Interventions: PROCEDURE: Endoscopic ultrasonography-guided ethanol lavage with paclitaxel injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Berberine in Reducing Abdominal Visceral Adipose Tissue Among Individuals With Obesity and NAFLD
Status: NOT_YET_RECRUITING
Conditions: Obesity|Obesity, Abdominal|NAFLD
Interventions: DRUG: Berberine plus lifestyle intervention|BEHAVIORAL: Placebo plus lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study Between Two Different Dosages of an Antiparasitic in Patients With Crusted Scabies
Status: COMPLETED
Conditions: Gale|Severe Forms of Scabies|Oral Parasitic Drug|Ivermectin
Interventions: DRUG: Ivermectin 200 µg/kg|DRUG: Ivermectin 400 µg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Inhaled Novaferon Study in Hospitalized Patients With Moderate to Severe COVID-19
Status: UNKNOWN
Conditions: Covid19
Interventions: BIOLOGICAL: Novaferon|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cervical Mobilization vs. Standard Physical Therapy for Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: PROCEDURE: Spinal mobilization|PROCEDURE: Massage|PROCEDURE: Neck exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Propagermanium in Diabetic Kidney Disease Participants Receiving Irbesartan
Status: COMPLETED
Conditions: Diabetic Kidney Disease
Interventions: DRUG: Propagermanium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Multi-centre Study to Assess the Safety and Manageability of a Laparoscopic Adhesion Barrier in Women Undergoing Gynecologic Laparoscopic Surgery Followed by Second Look Laparoscopy
Status: COMPLETED
Conditions: Tissue Adhesions
Interventions: DEVICE: LABS™|PROCEDURE: Surgical Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: GROW (Glioma Specialists Reaching Out With Support) Support
Status: WITHDRAWN
Conditions: Low-grade Glioma|Survivorship|Care Giving Burden
Interventions: BEHAVIORAL: GROW (Glioma Specialists Reaching Out With Support) Support Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of TENS on Myocardial Protection in Patients Undergoing AVR
Status: COMPLETED
Conditions: Myocardial Protection
Interventions: PROCEDURE: TENS (transcutaneous electrical nerve stimulation)|PROCEDURE: sham intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Changes in Biomarkers Associated With Use of Electronic Cigarettes
Status: COMPLETED
Conditions: Biomarkers
Interventions: DEVICE: E-Cig Zero Nicotine|DEVICE: E-Cig 24mg Nicotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: XmAb5871|BIOLOGICAL: Placebo to match XmAb5871
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Scalp Infiltration With Dexamethasone Plus Ropivacaine for Post-craniotomy Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain, Postoperative
Interventions: DRUG: Dexamethasone lipid microsphere plus ropivacaine|DRUG: Ropivacaine alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention, Randomized, Open Label, Active Control, Parallel Assignment, Safety/Efficacy Study
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: rMenB|BIOLOGICAL: rMenB+OMV|BIOLOGICAL: DTaP-Hib-IPV|BIOLOGICAL: PC7|BIOLOGICAL: MenC-CRM|BIOLOGICAL: MenC-Hib|BIOLOGICAL: MMR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase III Study to Evaluate Efficacy and Safety of TG-2349 in Combination With DAG181 and RBV for HCV Type I Patients
Status: COMPLETED
Conditions: Chronic Hepatics C Virus (HCV) Genotype 1|Non-Cirrhotic|Cirrhosis|Treatment naïve
Interventions: DRUG: TG-2349|DRUG: DAG181|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Topical Indomethacin Patch Over Placebo in Ankle Sprain Pain Relief
Status: COMPLETED
Conditions: Ankle Sprain
Interventions: DRUG: Indomethacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lot-to-lot Consistency of 23-valent Pneumococcal Polysaccharide Vaccine
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: Experimental 23-valent Pneumococcal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Weekly Carfilzomib, Cyclophosphamide and Dexamethasone In Newly Diagnosed Multiple Myeloma Patients (wCCyd)
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Cyclophosphamide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Test of Discomfort and Malaise of Two Different Urine Catheters in Healthy Volunteers
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DEVICE: Intermittent catheter CP063CC|DEVICE: SpeediCath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Potential Pharmacokinetic Interaction Between Selexipag and Midazolam in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Midazolam|DRUG: Selexipag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Coenzyme Q10 as Treatment for Long Term COVID-19
Status: COMPLETED
Conditions: Covid19|Long Term Covid19
Interventions: DRUG: Coenzyme Q10|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Interaction of Glucagon and Insulin on Endogenous Glucose Production in Humans
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 0.4mU Insulin followed by withdrawal period followed by 0.8mU study|DRUG: 0.8mU Insulin followed by withdrawal period followed by 0.4mU study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Mulligan Technique and Muscle Energy Technique in Lateral Epicondylitis
Status: COMPLETED
Conditions: Tennis Elbow
Interventions: OTHER: Mulligan Technique|OTHER: Muscle Energy Technique|OTHER: Only Exercise (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Pioglitazone
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Lixisenatide (AVE0010)|DRUG: Placebo|DEVICE: Pen auto-injector|DRUG: Pioglitazone|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical,Endoscopic and Radiological Assessment of Portal Hypertension in Children With Chronic Liver Diseases
Status: NOT_YET_RECRUITING
Conditions: Portal Hypertension
Interventions: DIAGNOSTIC_TEST: upper gastrointestinal endoscopy|DIAGNOSTIC_TEST: 1- Complete blood count 2- Coagulation profile
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Docetaxel/Epirubicin/Bevacizumab as First Line Therapy for Metastatic HER2 Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: Epirubicin|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Re-challenge of Anti-EGFR for Patients With RAS/BRAF Wild-type Metastatic CRC
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: C225+CPT-11
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ventricular Sling for Heart Failure With Reduced Ejection Fraction
Status: WITHDRAWN
Conditions: Heart Failure|Cardiomyopathy, Dilated
Interventions: DEVICE: Papillary Muscle Sling|PROCEDURE: CABG surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial of GI-4000 Plus Bevacizumab and Either FOLFOX or FOLFIRI
Status: TERMINATED
Conditions: Colon Cancer
Interventions: DRUG: chemotherapy and GI-4000|DRUG: GI-4000
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regional Anesthesia to Reduce Opioid Use Following Functional Endoscopic Sinus Surgery
Status: COMPLETED
Conditions: Pain Management
Interventions: DRUG: Bupivacaine|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Retrolaminar Block Versus Intraperitoneal Block for Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: PROCEDURE: retrolaminar block|PROCEDURE: Peritoneal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OPTIMA: Psychological Distress and the Effect of Intensive Group Based Cognitive Therapy in Patients With Newly Diagnosed Ischemic Heart Disease
Status: COMPLETED
Conditions: Ischemic Heart Disease|Heart Valve Diseases|Psychological Distress
Interventions: BEHAVIORAL: Group based cognitive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cancer Prevention in Women With a BRCA Mutation
Status: UNKNOWN
Conditions: BRCA1 Gene Mutation|BRCA2 Gene Mutation|Breast Cancer|Ovarian Cancer
Interventions: BEHAVIORAL: Follow-up Telephone Genetic Counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Verutex (Fusidic Acid), Eritex (Erythromycin) and Fisiogel in the Management of Tarceva-Associated Rash.
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: erlotinib [Tarceva]|DRUG: fusidic acid [Verutex]|DRUG: erythromycin [Eritex]|DRUG: Fisiogel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biweekly Intraperitoneal Oxaliplatin With Systemic Capecitabine and Bevacizumab for Patients With Peritoneal Carcinomatosis From Appendiceal or Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma
Interventions: DRUG: Intraperitoneal Oxaliplatin|DRUG: Bevacizumab|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Of Unstable Trochanteric Fracture: A Comparative Study Between DHS And DHS With Trochanteric Stabilization Plate
Status: RECRUITING
Conditions: Trochanteric Fractures
Interventions: PROCEDURE: dynamic hip screw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter RCT of the Clinical Effectiveness of Oncothermia With Chemotherapy in Metastatic Pancreatic Cancer Patients
Status: UNKNOWN
Conditions: Cancer, Pancreas
Interventions: OTHER: Oncothermia|DRUG: FOLFIRINOX or Gemcitabine based chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)
Status: COMPLETED
Conditions: Basal Cell Carcinoma|Gorlin Syndrome|Nevoid Basal Cell Carcinoma Syndrome
Interventions: DRUG: LDE225|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy With or Without Bicalutamide and Goserelin in Treating Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: bicalutamide|DRUG: goserelin acetate|PROCEDURE: assessment of therapy complications|PROCEDURE: quality-of-life assessment|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Voruciclib Alone or in Combination With Venetoclax in Subjects With B-Cell Malignancies or AML
Status: RECRUITING
Conditions: Follicular Lymphoma (FL)|Mantle Cell Lymphoma (MCL)|Marginal Zone Lymphoma (MZL)|Small Lymphocytic Lymphoma (SLL)|Chronic Lymphocytic Leukemia (CLL)|Diffuse Large B-cell Lymphoma (DLBCL)|Acute Myeloid Leukemia (AML)
Interventions: DRUG: voruciclib monotherapy|DRUG: voruciclib and venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT