pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Fluzoparib in Combination With or Without Camrelizumab for Homologous Recombinant Deficiency (HRD) HER2 Negative Advanced Breast Cancer
Status: RECRUITING
Conditions: Advanced HER2 Negative Breast Carcinoma HRD+Breast Cancer
Interventions: DRUG: Fluzoparib|DRUG: Fluzoparib+Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Pharmacodynamics of Desmopressin Oral Lyophilisate Formulation in the Paediatric Population
Status: COMPLETED
Conditions: Monosymptomatic Nocturnal Enuresis
Interventions: DRUG: desmopressin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ultrathin Bronchoscope and Radial Endobronchial Ultrasound (R-EBUS) With Fluoroscopy Versus Standard Fiberoptic Bronchoscopy (FB) (P00029233 )
Status: COMPLETED
Conditions: Pulmonary Lesions|Pulmonary Nodules|Pulmonary Mass
Interventions: DEVICE: Standard FB with fluoroscopy|DEVICE: R-EBUS with ultrathin bronchoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety Study of Nelfinavir + Cisplatin + Pelvic Radiation Therapy to Treat Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DRUG: Nelfinavir|DRUG: Cisplatin|RADIATION: Pelvic External Beam Radiation Therapy|RADIATION: Brachytherapy|PROCEDURE: Pharmacokinetic Sampling|PROCEDURE: Cervical Biopsy|PROCEDURE: Pelvic Examination|PROCEDURE: Pap Smear|PROCEDURE: Audiogram|PROCEDURE: Proctoscopy|PROCEDURE: Cytoscopy|PROCEDURE: Renal Ultrasound|PROCEDURE: CT Scan|PROCEDURE: Whole Body PET/CT Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: European Trial of Free Light Chain Removal by Extended Haemodialysis in Cast Nephropathy
Status: COMPLETED
Conditions: Multiple Myeloma|Cast Nephropathy|Kidney Failure
Interventions: DEVICE: FLC removal HD (Gambro HCO 1100)|PROCEDURE: Standard dialysis on a high flux ployflux dialyser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Legume Diet Satiety Pilot Study
Status: COMPLETED
Conditions: Obesity|Colorectal Carcinoma
Interventions: BEHAVIORAL: Legume diet group|BEHAVIORAL: Control diet group|DEVICE: Smartpill|OTHER: legumes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Arthroscopic Bankart Repair With and Without Remplissage in Anterior Shoulder Instability
Status: ACTIVE_NOT_RECRUITING
Conditions: Other Instability, Shoulder|Hill-Sachs Lesion
Interventions: PROCEDURE: Bankart repair and remplissage|PROCEDURE: Bankart repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Sotigalimab (APX005M) in Subjects With Unresectable or Metastatic Melanoma
Status: TERMINATED
Conditions: Unresectable Melanoma|Metastatic Melanoma|Cancer|Cancer of Skin|Melanoma|Melanoma (Skin)
Interventions: DRUG: sotigalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Mobile Phones for Thermal Imaging of the Chest to Save Lives of Children With Pneumonia in Nagpur, India
Status: COMPLETED
Conditions: Infections - Bacterial|Pneumonia - Bacterial
Interventions: DEVICE: FLIR ONE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Effectiveness and Tolerability of Boceprevir vs Telaprevir
Status: COMPLETED
Conditions: Hepatitis C, Chronic|Cirrhosis
Interventions: DRUG: Telaprevir|DRUG: Boceprevir|DRUG: Peg-IFN|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of NaF PET-CT and Diffusion MRI in the Diagnosis of Bone Metastases (IMMETAOS)
Status: COMPLETED
Conditions: Cancer|Bone Metastasis
Interventions: DEVICE: PET-CT|DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Comparing BL-M07D1 With T-DM1 in Patients With Unresectable Locally Advanced or Metastatic HER2-positive Breast Cancer
Status: RECRUITING
Conditions: HER2-positive Breast Cancer
Interventions: DRUG: BL-M07D1|DRUG: T-DM1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-4334 in Subjects With Chronic Hepatitis B Virus Infection
Status: NOT_YET_RECRUITING
Conditions: Chronic Hepatitis B
Interventions: DRUG: ABI-4334|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bypass Versus Endovascular Procedure in Long Lesions of the Superficial Femoral Artery in the Claudicant
Status: NOT_YET_RECRUITING
Conditions: Lesion; Femoral
Interventions: PROCEDURE: Femoro-popliteal bypass|PROCEDURE: Endovascular procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mirena and Estrogen for Control of Perimenopause Symptoms and Ovulation Suppression
Status: COMPLETED
Conditions: Menopausal and Other Perimenopausal Disorders
Interventions: DRUG: Mirena|DRUG: Estradiol|DRUG: Placebo Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Chlorhexidine in Minimizing the Viral Load Among COVID-19 Patients
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Chlorhexidine digluconate, povidone iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Utility of Pediatric Whole Exome Sequencing
Status: COMPLETED
Conditions: Encephalopathy|Birth Defect|Intellectual Disability|Multiple Congenital Anomaly|Metabolic Disease|Epilepsy|Neuro-Degenerative Disease|Cerebral Palsy|Developmental Delay|Developmental Defect
Interventions: DIAGNOSTIC_TEST: Whole Exome Sequencing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: EMDR Pre-treatment Yoga for Complex Trauma
Status: RECRUITING
Conditions: Trauma, Psychological
Interventions: OTHER: 10 Sessions of yogatherapy associate with EMDR|OTHER: The second group will have EMDR without yogatherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Immunogenicity of the Butantan Quadrivalent Influenza Vaccine
Status: ACTIVE_NOT_RECRUITING
Conditions: Influenza, Human
Interventions: BIOLOGICAL: QIV-IB|BIOLOGICAL: TIVV-IB|BIOLOGICAL: TIVY-IB|BIOLOGICAL: QIV-IB Lot A|BIOLOGICAL: QIV-IB Lot B|BIOLOGICAL: QIV-IB Lot C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Evaluation of LSCD101 Transplantation for Limbal Stem Cell Deficiency
Status: COMPLETED
Conditions: Limbus Corneae|Limbus Corneae Insufficiency Syndrome
Interventions: DRUG: LSCD101 (Cultured Autologous Limbal Epithelial Cell Sheet) transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Danirixin Co-administered With Oseltamivir in the Treatment of Adults Hospitalized With Influenza
Status: TERMINATED
Conditions: Virus Diseases
Interventions: DRUG: Danirixin 15 mg FBE|DRUG: Danirixin 50 mg FBE|DRUG: Placebo|DRUG: Oseltamivir 75 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Interest of Interleukine-2 for Patients With Active Warm Hemolytic Anemia Resistant to Conventional Treatment
Status: COMPLETED
Conditions: Autoimmune Hemolytic Anemia
Interventions: DRUG: Interleukine-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radicle Clarity 24: A Study of Health and Wellness Products on Cognitive Function and Related Health Outcomes
Status: RECRUITING
Conditions: Cognitive Function
Interventions: DIETARY_SUPPLEMENT: Placebo Control Form 1|DIETARY_SUPPLEMENT: Clarity Active Study Product 1.1 Usage|DIETARY_SUPPLEMENT: Placebo Control Form 2|DIETARY_SUPPLEMENT: Clarity Active Study Product 2.1 Usage|DIETARY_SUPPLEMENT: Placebo Control Form 3|DIETARY_SUPPLEMENT: Clarity Active Study Product 3.1 Usage|DIETARY_SUPPLEMENT: Clarity Active Study Product 3.2 Usage|DIETARY_SUPPLEMENT: Placebo Control Form 4|DIETARY_SUPPLEMENT: Clarity Active Study Product 4.1 Usage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Combination of Capecitabine and Oxaliplatin in Metastatic Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Neoplasms
Interventions: DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integration of Education Based-Application and "CARE Coaching Model" in Management of Type 2 Diabetes Mellitus Patients Using Insulin
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Mobile Application-Based Diabetes Education|OTHER: Health Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparative Study Efficacy and Safety of of Activated Versus Non-Activated PRP
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: Intradermal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Beacon BNX™ Endoscopic Ultrasound (EUS)-Needle vs SharkCore™ Needle
Status: TERMINATED
Conditions: Pancreatic Cancer|Lymphadenopathy|Cholangiocarcinoma
Interventions: DEVICE: 22G SharkCore™ needle|DEVICE: 22G BNX EUS-FNA Needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Gas Consumption From Two Different Anesthesia Machines
Status: COMPLETED
Conditions: Male Urogenital Diseases|Female Urogenital Diseases
Interventions: DEVICE: Aisys with Et control|DEVICE: Aisys conventional|DEVICE: Flow-i with ACG|DEVICE: Flow-i conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Early Loading of Implants in the Maxillary Anterior Region With Alveolar Bone Defects
Status: RECRUITING
Conditions: Dental Implant
Interventions: DEVICE: Temporary Crown|DEVICE: Permanent Crown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FTIH of ECC5004 in Healthy and Diabetic Participants
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Placebo|DRUG: ECC5004
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of PN400 (VIMOVO) Twice Daily and Celebrex Once Daily in Patients With Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: PN 400 (VIMOVO)|DRUG: celebrex|OTHER: Placebo|DRUG: Rescue Antacid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Exercise Capacity in Patients With Severe Emphysema Treated With Coils
Status: UNKNOWN
Conditions: Pulmonary Emphysema
Interventions: PROCEDURE: 10 coils in upper lobes|PROCEDURE: 15 coils in upper and lower lobes|PROCEDURE: cycloergometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Piperacillin Sodium and Sulbactam Sodium for Injection (2:1) for Treatment of Respiratory and Urinary Tract Infection
Status: UNKNOWN
Conditions: Respiratory Tract Infections|Urinary Tract Infections
Interventions: DRUG: xin te mie
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Corifollitropin Alfa (MK-8962) in Combination With Human Chorionic Gonadotropin (hCG) in Adult Men With Hypogonadotropic Hypogonadism (HH) (P07937)
Status: COMPLETED
Conditions: Hypogonadism|Hypogonadotropic Hypogonadism
Interventions: DRUG: Corifollitropin alfa|DRUG: hCG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Perioperative Analgesia Platform (PPAP) for Cesarean Section
Status: RECRUITING
Conditions: Cesarean Section Complications|Opioid Use
Interventions: DIAGNOSTIC_TEST: Preoperative Genotyping
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Multiple Doses of Somapacitan in Subjects With Mild and Moderate Degrees of Hepatic Impairment Compared to Subjects With Normal Hepatic Function.
Status: COMPLETED
Conditions: Growth Hormone Disorder|Adult Growth Hormone Deficiency|Growth Hormone Deficiency in Children
Interventions: DRUG: Somapacitan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Feasibility & Validation of the Virtual Reality GlenxRose Speech-Language Therapies
Status: RECRUITING
Conditions: Vocal Cord Dysfunction|Speech Disorders
Interventions: DEVICE: GlenXRose Virtual Reality Speech Therapies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Redosing With CP-870, 893 in Patients With Clinical Benefit After a Single Infusion From A Phase I, Open-Label, Dose-Escalation Study of CP-870,893 in Patients With Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: BIOLOGICAL: CP-870,893
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Immunogenicity of Tau Targeted Vaccines in Participants With Early Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease|Cognitive Impairment|Tauopathies|Mild Cognitive Impairment|Dementia|Brain Diseases|Central Nervous System Diseases
Interventions: BIOLOGICAL: ACI-35.030|BIOLOGICAL: ACI-35.030|BIOLOGICAL: ACI-35.030|OTHER: Placebo|BIOLOGICAL: JACI-35.054|BIOLOGICAL: JACI-35.054
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brexpiprazole (OPC-34712) as an Adjunctive Treatment in Adults With Major Depressive Disorder and Anxiety Symptoms
Status: COMPLETED
Conditions: Major Depressive Disorder|Anxiety
Interventions: DRUG: Brexpiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Assessment of the Safety and Performance of the NuVasive Simplify Disc at Two Levels
Status: ENROLLING_BY_INVITATION
Conditions: Cervical Disc Disease|Degenerative Disc Disease
Interventions: DEVICE: NuVasive Simplify Cervical Artificial Disc
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oblimersen in Treating Patients With Merkel Cell Carcinoma
Status: COMPLETED
Conditions: Recurrent Neuroendocrine Carcinoma of the Skin|Stage I Neuroendocrine Carcinoma of the Skin|Stage II Neuroendocrine Carcinoma of the Skin|Stage III Neuroendocrine Carcinoma of the Skin|Stage IV Neuroendocrine Carcinoma of the Skin
Interventions: BIOLOGICAL: oblimersen sodium|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Flow Nasal Cannula vs Noninvasive Ventilation in Patients With Hypoxic Respiratory Failure Following Blunt Chest Trauma
Status: COMPLETED
Conditions: Blunt Injury of Thorax
Interventions: DEVICE: high flow nasal cannula|DEVICE: noninvasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of the Ensure Medical Vascular Closure Device
Status: COMPLETED
Conditions: Angioplasty, Transluminal, Percutaneous Coronary|Coronary Arteriosclerosis|Peripheral Arteriosclerosis
Interventions: OTHER: Manual Compression|DEVICE: Vascular Closure Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SWOG-9704 Chemoradiotherapy and Peripheral Stem Cell Transplantation Compared With Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: CHOP regimen|DRUG: carmustine|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: prednisone|DRUG: vincristine sulfate|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ocular Findings in Patients Between Surgical and Natural Menopause
Status: COMPLETED
Conditions: Menopause Surgical|Macula Edema|Visual Acuity Reduced Transiently
Interventions: DIAGNOSTIC_TEST: measurement of macular thickness, corneal thickness and lens opacities
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pulsed Radiofrequency for Frozen Shoulder Chronic Pain (PRFFSCP)
Status: UNKNOWN
Conditions: Frozen Shoulder
Interventions: DEVICE: pulsed radiofrequency|DRUG: NSAIDs "ibubrofen,Aspirin"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of B-CLL With Autologous IL2 and CD40 Ligand-Expressing Tumor Cells + Lenalidomide
Status: TERMINATED
Conditions: B-cell Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: B-CLL Vaccine|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TMW Community-Wide Demonstration Project
Status: WITHDRAWN
Conditions: Language Development
Interventions: BEHAVIORAL: 3Ts - Newborn|BEHAVIORAL: 3Ts - Well Baby|BEHAVIORAL: 3Ts - Let's Talk!
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Pharmacodynamic Effects of SAGE-217 in Healthy Adults Using an Insomnia Model
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SAGE-217 high dose|DRUG: Placebo|DRUG: SAGE-217 low dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ESP Block Versus Wound Infiltration for Laminectomy
Status: UNKNOWN
Conditions: Pain, Postoperative|Opioid Use|Anesthesia, Local|Surgery
Interventions: DRUG: ESP block with saline|DRUG: Wound infiltration with saline|DRUG: ESP block with local anesthetic|DRUG: Wound infiltration with local anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Evaluation of Liver Fibrosis, Steatosis, and NASH in NAFLD
Status: UNKNOWN
Conditions: Nonalcoholic Fatty Liver|Nonalcoholic Steatohepatitis
Interventions: DIAGNOSTIC_TEST: Imaging and serologic evaluation of fibrosis and steatosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinsons Disease
Interventions: DRUG: Prasinezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine, Oxaliplatin in Combination With Bevacizumab in Biliary Tract and Gallbladder Cancer
Status: COMPLETED
Conditions: Biliary Tract Cancer|Gallbladder Adenocarcinoma
Interventions: DRUG: Bevacizumab|DRUG: Gemcitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study of Long-term Safety and Tolerability of Octreotide Acetate in Patients With Moderately Severe or Severe Non-proliferative Diabetic Retinopathy or Low Risk Proliferative Diabetic Retinopathy
Status: TERMINATED
Conditions: Diabetic Retinopathy
Interventions: DRUG: Octreotide acetate in microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Oral Rigosertib in Transfusion-dependent, Low or Int-1 or Trisomy 8 Int-2 Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|MDS|Trisomy 8
Interventions: DRUG: rigosertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Absolute Oral Bioavailability of Quizartinib Using a Radiolabeled Microtracer in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Quizartinib dihydrochloride|DRUG: 14C-Quizartinib solution for infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cannabidiol Treatment of Cognitive Dysfunction in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Cannabidiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Safety and Efficacy of EXG001-307 in Patients With Spinal Muscular Atrophy Type 1
Status: RECRUITING
Conditions: Spinal Muscular Atrophy Type I
Interventions: GENETIC: EXG001-307 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parameter Space of kTMP
Status: ENROLLING_BY_INVITATION
Conditions: Healthy
Interventions: DEVICE: kTMP|DEVICE: Sham kTMP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effect of Intravenous Lignocaine Infusion on Intraoperative End Tidal Desflurane Concentration Requirements
Status: COMPLETED
Conditions: Cholelithiases|Appendicitis|Ovarian Cysts
Interventions: DRUG: Lignocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Persistent Pleural Effusion Treatment Following Cardiothoracic Surgery by Platelet-Fibrin Glue
Status: COMPLETED
Conditions: Pleural Effusion
Interventions: DRUG: Platelet-Rich Plasma and Fibrin Glue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Carbidopa/Levodopa/Entacapone Combination vs. Carbidopa/Levodopa Combination Plus Entacapone in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ELC200 (carbidopa+levodopa+entacapone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hip Joint Mobilizations and Strength Training in Patients With Knee OA Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Hip Joint Mobilizations|OTHER: Hip joint Muscle strength training|OTHER: knee strengthening and flexibility exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comedone Extraction and Oral Doxycycline In The First Line Treatment of Moderate Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Doxycycline Capsule|PROCEDURE: Comedone extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Model System for Transient Forearm Blood Vessel Dysfunction
Status: COMPLETED
Conditions: Limb Ischemia|Ischemic Preconditioning
Interventions: PROCEDURE: Limb Ischemia|DRUG: Acetylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The CHARM Trial: Chemotherapy for Ablation and Resolution of Mucinous Pancreatic Cysts
Status: COMPLETED
Conditions: Mucinous Pancreatic Cysts
Interventions: DRUG: Ethanol|DRUG: Normal Saline|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Down-regulated Hormonally Controlled Cycles for Vitrification-warmed Blastocyst Transfers
Status: WITHDRAWN
Conditions: Pregnancy
Interventions: DRUG: Lucrin depot|DRUG: OCP|OTHER: Natural
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Low Power Laser in the Pain After Lower Tooth Extraction
Status: COMPLETED
Conditions: Third Molar Extraction|Oral Pain|Tooth Extraction
Interventions: RADIATION: Low frequency laser activated photobiomodulation|OTHER: Low frequency laser photobiomodulation inactive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I/II Study of Paclitaxel, Carboplatin and YM155 (Survivin Suppressor) in Subjects With Solid Tumors (Phase I) and Advanced Non-Small Cell Lung Carcinoma (Phase II)
Status: COMPLETED
Conditions: NSCLC|Solid Tumors
Interventions: DRUG: YM155|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aldosterone Blockade to Prevent Myocardial Remodeling In Patients With Controlled Essential Hypertension
Status: TERMINATED
Conditions: Myocardial Remodeling
Interventions: DRUG: Eplerenone|DRUG: Lactose Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A RAndomizeD Intervention for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients
Status: RECRUITING
Conditions: Prostate Cancer|Cardiovascular Disease
Interventions: BEHAVIORAL: Nutrition|BEHAVIORAL: Exercise|BEHAVIORAL: Smoking cessation|DRUG: Statin (such as Simvastatin, Atorvastatin, Rosuvastatin, Pravastatin)|DRUG: ACE inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Blood Phobia on Fainting Susceptibility
Status: RECRUITING
Conditions: Syncope, Vasovagal|Blood, Injection, Injury Type Phobia
Interventions: OTHER: blood-injection-injury (BII) phobia stimuli|OTHER: neutral stimuli
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Efficacy and Safety Study of Two Doses of Intra-Articular Ampion Injection for Pain of Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: BIOLOGICAL: 4 mL injection of Ampion|BIOLOGICAL: 10 mL Injection of Ampion|DRUG: 4 mL Injection of Placebo|DRUG: 10 mL Injection of Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Donor Umbilical Cord Blood Transplant After Cyclophosphamide, Fludarabine Phosphate, and Total-Body Irradiation in Treating Patients With Hematologic Disease
Status: UNKNOWN
Conditions: Hematopoietic/Lymphoid Cancer
Interventions: DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: mycophenolate mofetil|OTHER: laboratory biomarker analysis|PROCEDURE: nonmyeloablative allogeneic hematopoietic stem cell transplantation|PROCEDURE: umbilical cord blood transplantation|RADIATION: total-body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ponatinib in Adult Ph+ ALL Patients With MRD Positivity or Hematological Relapse
Status: RECRUITING
Conditions: Philadelphia-Positive ALL|Acute Lymphoblastic Leukemia, in Relapse
Interventions: DRUG: Ponatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Furosemide Versus Ethacrynic Acid in Children With Congenital Heart Disease
Status: COMPLETED
Conditions: Fluid Overload
Interventions: DRUG: furosemide|DRUG: ethacrynic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Classical Procedure Versus Intrahepatic Glisson's Approach
Status: UNKNOWN
Conditions: Liver Diseases|Liver Neoplasms|Hepatic Haemangioma
Interventions: PROCEDURE: intrahepatic Glisson's approach|PROCEDURE: classical hepatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Supporting Older Spousal Caregivers Who Care for a Partner With Multimorbidity at Home
Status: ACTIVE_NOT_RECRUITING
Conditions: Family Members|Home Care Services|Support, Family
Interventions: OTHER: The Carer Support Needs Assessment Tool Intervention (CSNAT-I)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Elotuzumab Plus Lenalidomide (Elo/Rev) for Serologic Relapse/Progression While on Lenalidomide
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Elotuzumab|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RItuximab Versus Ocrelizumab in Relapsing-remitting Multiple Sclerosis.
Status: RECRUITING
Conditions: Multiple Sclerosis|Relapsing-remitting Multiple Sclerosis
Interventions: DRUG: Perfusion of treatment Rituximab|DRUG: Perfusion of treatment Ocrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Treatments for Suicidal Veterans With PTSD
Status: RECRUITING
Conditions: Self-directed Violence|Post-traumatic Stress Disorder (PTSD)
Interventions: BEHAVIORAL: Dialectical Behavior Therapy|BEHAVIORAL: Dialectical Behavior Therapy Prolonged Exposure protocol|BEHAVIORAL: Prolonged Exposure therapy|BEHAVIORAL: Suicide risk management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability and Pharmacokinetics and Pharmacodynamics of AZD0284 in Healthy Subjects
Status: COMPLETED
Conditions: Plaque Psoriasis Vulgaris
Interventions: DRUG: AZD0284|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Flexibility: A Study to Assess the Impact of Darbepoetin Alfa in Subjects withNon-Myeloid Malignancies With Anemia Due to Chemotherapy
Status: COMPLETED
Conditions: Anemia|Cancer
Interventions: DRUG: Aranesp®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Investigation of a Multinutrient Supplement on Skin Aging and Aging Metabolites in Healthy Women
Status: COMPLETED
Conditions: Skin Diseases
Interventions: DRUG: Dietary Supplement: LifePak Nano
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Tiopronin on 3-Aminopropanal Level & Neurologic Outcome After Aneurysmal Subarachnoid Hemorrhage
Status: COMPLETED
Conditions: Aneurysmal Subarachnoid Hemorrhage
Interventions: DRUG: Tiopronin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Functional Outcomes Study With Atomoxetine-Hydrochloride and Placebo in Adults With Attention-Deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Atomoxetine Hydrochloride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study for Evaluation of Murlentamab (GM102) Anti-tumoral Activity in Colorectal Cancers
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: GM102|DRUG: Trifluridine/Tipiracil|DRUG: GM102 expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Revian Red All LED Cap as a Novel Treatment for Central Centrifugal Cicatricial Alopecia
Status: RECRUITING
Conditions: Central Centrifugal Cicatricial Alopecia
Interventions: DEVICE: Revian Red All LED cap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bee Venom Acupuncture for the Treatment of Frozen Shoulder
Status: COMPLETED
Conditions: Frozen Shoulder
Interventions: PROCEDURE: 1:10,000 bee venom (BV) acupuncture|PROCEDURE: 1:30,000 bee venom (BV) acupuncture|PROCEDURE: normal saline injection|PROCEDURE: physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study for Evaluating Colon Polyp Histology With in Vivo Probe Based Confocal Laser Endomicroscopy
Status: UNKNOWN
Conditions: Colon Polyps|Adenomatous Polyps|Colon Cancer
Interventions: DEVICE: Confocal laser endomicroscopy (CLE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Treatment of Intrapartum Depression Using Non-invasive Photobiomodulation
Status: UNKNOWN
Conditions: Depression|Pregnancy Related|Intrapartum Depression
Interventions: RADIATION: Delivery of infrared light to the head|OTHER: No Infrared treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomolecular Characteristics of Reminder-Focused Positive-Psychiatry
Status: UNKNOWN
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Reminder Focused Positive Psychiatry|BEHAVIORAL: attentional control condition (group process)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Liraglutide Versus Lixisenatide as add-on to Metformin in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide|DRUG: lixisenatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of BCG Vaccine for Immune-prophylaxis Among Egyptian Healthcare Workers During the Pandemic of COVID-19
Status: UNKNOWN
Conditions: Coronavirus Disease (COVID-19)
Interventions: BIOLOGICAL: intradermal injection of BCG Vaccine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Single and Double Injection Bilateral Thoracic Paravertebral Blocks in Reduction Mammaplasty
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Thoracic paravertebral block-single injection|PROCEDURE: Thoracic paravertebral block-double injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: EFFECTIVENESS AND SAFETY OF CREAM CONTAINING SPENT GRAIN WAX EXTRACT, ARGAN OIL, AND SHEA BUTTER POST-TRICHOLOROACETIC ACID 15% PEEL: RANDOMIZED, CONTROLLED, DOUBLE-BLIND, SPLIT-FACE CLINICAL TRIAL
Status: COMPLETED
Conditions: Aging Disorder
Interventions: DRUG: Ezerra cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Novel MRI Strategies as a Non-invasive Biomarker in Women With Uterine Fibroids
Status: COMPLETED
Conditions: Fibroid|Leiomyoma
Interventions: DRUG: GnRH analogue (Zoladex)|DRUG: GnRH antagonist-Cetrorelix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effect Of Carvedilol Versus Metoprolol On Glycemic Control In Patients With Type II Diabetes And Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: carvedilol|DRUG: metoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of EXG-5003
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: EXG-5003|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Serum Irisin in Myocardial Infraction and Following Percutaneous Coronary Intevention
Status: COMPLETED
Conditions: Myocardial Infarction|Coronary Artery Disease
Interventions: PROCEDURE: percutaneous coronary intervention|PROCEDURE: coronary angiography|DEVICE: Stent, Medronic Resolute Integrity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Broccoli Sprouts for Mild Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis|Ulcerative Colitis Chronic Mild
Interventions: DIETARY_SUPPLEMENT: 1 Serving of broccoli sprouts|DIETARY_SUPPLEMENT: 3 Servings of broccoli sprouts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nab-paclitaxel Combined With Oxaliplatin and S-1 for Perioperative Treatment of Advanced Gastric Cancer
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Nab-paclitaxel combined with oxaliplatin and S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical Versus Nonsurgical Treatment on Quality of Life for Children With Controversial OSA Diagnoses
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea of Child
Interventions: PROCEDURE: adenotonsillectomy|OTHER: Nonsurgical management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Surgery and the Risk of Atrial Fibrillation: an Intervention Trial Evaluating Melatonin
Status: WITHDRAWN
Conditions: Atrial Fibrillation
Interventions: DRUG: Melatonin|DRUG: Placebo (for Melatonin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Screening for Amyloidosis Before Aortic Valve Elective Replacement
Status: ACTIVE_NOT_RECRUITING
Conditions: Amyloidosis|Aortic Valve Stenosis
Interventions: OTHER: The outcome of an intervention is not evaluated, but aortic stenosis and additional amyloidosis are compared.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial Scheme of Xinnaoning Capsule
Status: UNKNOWN
Conditions: Chronic Stable Angina Pectoris|Qi Stagnation and Blood Stasis Syndrome
Interventions: DRUG: Xinnaoning Capsule|OTHER: Xinnaoning Capsule Simulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Vitamin A and Carbomer in Comforting the Ocular Surface Irritations of Glaucoma Patients
Status: COMPLETED
Conditions: Primary Open-angle Glaucoma
Interventions: DRUG: Vitamin A|DRUG: carbomer eye gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Safety and Efficacy Study of Single-agent AT-101 in Patients With Relapsed or Refractory B-cell Malignancies
Status: COMPLETED
Conditions: Follicular Lymphoma|Diffuse Large Cell Lymphoma|Mantle Cell Lymphoma|Small Lymphocytic Lymphoma|Chronic Lymphocytic Leukemia
Interventions: DRUG: AT-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Using Fractional Carbon Dioxide and Long Pulsed Neodymium-yttrium Aluminum Garnet Lasers in Treatment of Keloids
Status: COMPLETED
Conditions: Keloid
Interventions: DEVICE: fractional CO2 laser 10,600nm|DEVICE: Nd YAG laser1064 nm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transfusion Savings in Heart Surgery: Impact of Individual Strategy by Erythropoietin and Metabolic Adjustment (ScvO2)
Status: COMPLETED
Conditions: Cardiac Surgery|Transfusion|Perioperative Anemia
Interventions: DRUG: EPO (600UI/Kg, sub-cutaneous) and Ferric Carboxymaltose (FCM) (20 mg/kg in 250 mL of saline solution 0.9% over 15 min)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cognitive-motor Training on Cognition, Depression and Daily Functioning in Patients With Mild Cognitive Impairment (MCI)
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: cognitive training via immersive virtual reality|OTHER: cognitive training via paper and pencil|OTHER: motor stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential Treatment of Psoriasis With Integrated Traditional Chinese and Western Medicine
Status: UNKNOWN
Conditions: Plaque Psoriasis
Interventions: DRUG: Jueyin granules|DEVICE: moving cupping therapy|DEVICE: NB-UVB therapy|DRUG: Jueyin placebo granules|DEVICE: moving cupping placebo therapy|DEVICE: NB-UVB placebo phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Learning to Talk, Learning to Eat: A Randomized Controlled Trial to Improve NICU Oral Feeding and Language Outcomes
Status: NOT_YET_RECRUITING
Conditions: Language Delay|Language Development|Feeding; Difficult, Newborn|Mother-Infant Interaction|Maternal Behavior
Interventions: BEHAVIORAL: Oromotor stimulation|BEHAVIORAL: Reading curriculum|BEHAVIORAL: LENA recording|BEHAVIORAL: LENA linguistic feedback|BEHAVIORAL: No oromotor stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of ALXN2220 Versus Placebo in Adults With ATTR-CM
Status: RECRUITING
Conditions: Transthyretin Amyloid Cardiomyopathy
Interventions: DRUG: ALXN2220|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Factors II, VII, IX, X, and Proteins C and S, Following High-dose Vitamin K Supplementation
Status: COMPLETED
Conditions: Thrombosis
Interventions: DIETARY_SUPPLEMENT: Vitamin K, 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE