pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Parkinson's Disease and Gamma-transcranial Alternating Current Stimulation
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: gamma transcranial alternating current stimulation (tACS)|DEVICE: sham transcranial alternating current stimulation (tACS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation of QT Dispersion With Myocardial Perfusion in Patients With ST Elevation Myocardial Infarction Treated by Primary Per Cutaneous Coronary Intervention
Status: UNKNOWN
Conditions: ST Elevation Myocardial Infarction
Interventions: DIAGNOSTIC_TEST: ECG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stenosis of Arteria-Venous Fistula in Maintenance Hemodialysis Patients: Early Intervention Trial
Status: UNKNOWN
Conditions: Uremia|Arteriovenous Fistula|Stenosis
Interventions: DEVICE: DSA guided percutaneous balloon dilatation|DEVICE: Ultrasound guided percutaneous balloon dilatation|PROCEDURE: Surgical reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Castor Oil as a Labor Initiator in Post-date Pregnancies
Status: COMPLETED
Conditions: Prolonged Pregnancy
Interventions: DIETARY_SUPPLEMENT: Castor oil|DIETARY_SUPPLEMENT: Sunflower oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Muscle Energy Techniques on Functional Abilities in Patients With Discogenic Unilateral Sciatica
Status: COMPLETED
Conditions: Sciatica|Low Back Pain
Interventions: OTHER: Conventional program|OTHER: Muscle energy technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Promising New Combination of Protein Kinase Inhibitors on Organotypic Cultures of Human Renal Tumors
Status: RECRUITING
Conditions: Kidney Cancer
Interventions: COMBINATION_PRODUCT: CK2 and ATM inhibitors serine/ threonin Kinase combination|DRUG: Sunitinib|DRUG: Pazopanib|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Cardiovascular Risk Stratification in Young People With Type 1 Diabetes by Coronary Calcium Score to ESC/ESA2019 Recommendations
Status: RECRUITING
Conditions: Type 1 Diabetes|Coronary Artery Calcification
Interventions: DIAGNOSTIC_TEST: Coronary Artery Calcification Realization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Azithromycin in the Treatment of Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: 1% Azithromycin gel|DRUG: Azithromycin|DRUG: placebo gel|DRUG: placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Velcade + Cyclophosphamide in Newly Diagnosed Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Velcade|DRUG: Cyclophosphamide|DRUG: Revlimid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Second-line FOLFOX With or Without Regorafenib in mCRC Patients Failed to First-line Irinotecan Plus Fluoropyrimidines
Status: WITHDRAWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Regorafenib/FOLFOX|DRUG: Placebo/FOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Psychosocial Intervention for Suicidal Ideation in Individuals With FEP: A Feasibility Trial
Status: RECRUITING
Conditions: Self Harm, First Episode Psychosis
Interventions: BEHAVIORAL: CMAP Plus CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: pBFS-guided cTBS Combined With iTBS Over the Superior Frontal Gyrus for Aphasia After Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke, Ischemic|Aphasia
Interventions: DEVICE: active cTBS combined with iTBS|DEVICE: sham cTBS combined with iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Initial Education for Rehabilitation and Motivation Program Following a Myocardial Infarction Via SMS or Hospital
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: OTHER: Rehabilitation at home via SMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: High vs Low Dose Dexamethasone on Complications in the Immediate Postoperative Phase
Status: COMPLETED
Conditions: Hip Dysplasia|Postoperative Complications
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Toleration and Time Course of Plasma Concentration of Multiple Oral Doses of PF-06273340 in Healthy Subjects of Two AgeGroups, Aged 18-55 Years (Group 1) and Aged 56-75 Years (Group 2)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06273340|DRUG: Placebo|DRUG: PF-06273340|DRUG: Placebo|DRUG: PF-06273340|DRUG: Placebo|DRUG: PF-06273340|DRUG: Placebo|DRUG: PF-06273340|DRUG: Placebo|DRUG: PF-06273340|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Standardization of Laparoscopic Surgery for Right Hemi Colon Cancer (SLRC)
Status: UNKNOWN
Conditions: Overall Survival|Postoperative Complications|Metastasis|Stage, Colon Cancer
Interventions: PROCEDURE: CME|PROCEDURE: D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RISE (Reinvent, Integrate, Strengthen, Expand) Self-Management Program for Cancer Survivors: A Feasibility Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer|Survivorship
Interventions: OTHER: RISE (Reinvent, Integrate, Strengthen, Expand) Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Safety, Reactogenicity, and Immunogenicity Study of mRNA-1073 (COVID-19/Influenza) Vaccine in Adults 18 to 75 Years Old
Status: COMPLETED
Conditions: SARS-CoV-2|Influenza
Interventions: BIOLOGICAL: mRNA-1073|BIOLOGICAL: mRNA-1010|BIOLOGICAL: mRNA-1273|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency and Security of NIVOLUMAB Therapy in Obese Individuals With COVID-19(COrona VIrus Disease) Infection
Status: UNKNOWN
Conditions: Obesity, COVID-19 Infection
Interventions: DRUG: NIVOLUMAB|OTHER: Routine standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Deep Brain Stimulation on Gait of Patients With Parkinson's Disease Depending on Electrode Location in Subthalamic Area
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: BEHAVIORAL: deep brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hydrochlorothiazide as add-on to Olmesartan/Amlodipine in Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Olmesartan medoxomil 40 mg - Amlodipine 10 mg|DRUG: Olmesartan 40mg-Amlodipine 10mg-Hydrochlorothiazide 12.5mg|DRUG: Olmesartan 40mg-Amlodipine 10mg-Hydrochlorothiazide 25mg|DRUG: OLM 40mg-AML 10mg-Hydrochlorothiazide 12.5mg|DRUG: OLM 40mg-AML 10mg-Hydrochlorothiazide 12.5mg|DRUG: OLM 40mg-AML 10mg-Hydrochlorothiazide 25mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Supplemental Calcium in Overweight People
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Calcium supplement|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Individualized Management With Pegylated-interferon Alfa-2a (Pegasys) and Ribavirin (Copegus) Offering Viral Eradication: A Study of Pegylated-interferon Alfa-2a Plus Ribavirin in Participants With Chronic Hepatitis C (CHC) Non-genotype 2/3 (IMPROVE)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Pegylated-interferon Alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Show Equivalence of DERMABOND PROTAPE to DERMABOND HVD for Wound Closure
Status: COMPLETED
Conditions: Lacerations
Interventions: DEVICE: cyanoacrylate with pressure sensitive mesh|DEVICE: cyanoacrylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sildenafil Effect After Ovulation Induction
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: Clomiphene citrate|DRUG: sildenafil citrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of the Combination of Retinoic Acid and Interferon-Alpha2a for the Treatment of Lymphoproliferative Disorders in Children With Immunodeficiency Syndromes
Status: COMPLETED
Conditions: HIV Infections|Immunologic Deficiency Syndromes|Lymphoproliferative Disorders
Interventions: DRUG: all-trans-retinoic acid with IFN-alpha2a
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Blood Bioavailability of Two Different Doses of a β-alanine Supplement (BIo-β)
Status: COMPLETED
Conditions: Bioavailability
Interventions: DIETARY_SUPPLEMENT: Low dose|DIETARY_SUPPLEMENT: High dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Cognitive Behavioral Therapy for Post Traumatic Stress Disorder in Addiction Treatment
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Substance-Related Disorders
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for PTSD|BEHAVIORAL: Individual Addiction Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: No Code Artificial Intelligence to Detect Radiographic Features Associated With Unsatisfactory Endodontic Treatment
Status: NOT_YET_RECRUITING
Conditions: Endodontically Treated Teeth|Endodontic Underfill|Endodontic Overfill|Apical Periodontitis
Interventions: DEVICE: AI guidance for finding radiographic features
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Early Liver Support With MARS in Post-hepatectomy Liver Failure
Status: UNKNOWN
Conditions: Liver Failure as A Complication of Care
Interventions: DEVICE: Molecular Adsorbent Recirculating System|OTHER: Standard medical treatment (SMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Nicotinamide Riboside on Immunity
Status: COMPLETED
Conditions: Atherosclerosis|Diabetes|Coronary Artery Disease
Interventions: DIETARY_SUPPLEMENT: Nicotinamide riboside (NR)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 2/3 Study of IGSC, 20% in PIDD
Status: COMPLETED
Conditions: Primary Immunodeficiency Diseases (PID)
Interventions: BIOLOGICAL: Immune Globulin Intravenous (Human), 10% Solution|DRUG: Immune Globulin Subcutaneous (Human), 20% Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determinants of the Vascular Response to Training in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: RECRUITING
Conditions: COPD Patients|Healthy
Interventions: OTHER: FMD analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect Of Transcutaneous Auricular Vagus Nerve Stimulation On Sports Performance And Physiological Parameters
Status: COMPLETED
Conditions: Healthy|Activity, Motor
Interventions: DEVICE: Auricular Vagus Nerve Stimulation Level Of Above Threshold|DEVICE: Auricular Vagus Nerve Stimulation Level Of Subthreshold|DEVICE: Auricular Vagus Nerve Stimulation Sham Method|DIAGNOSTIC_TEST: 5 Minutes Bicycle Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Craniofacial Imaging With 3D MRI: an Alternative to Ionising Radiation
Status: UNKNOWN
Conditions: Craniosynostoses|Synostosis|Skull Deformity
Interventions: DIAGNOSTIC_TEST: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Determine the Utility of Liquid Biopsies and Tumor Molecular Profiling in Predicting Recurrence in High-Risk Endometrial Cancers
Status: RECRUITING
Conditions: Endometrial Clear Cell Adenocarcinoma|Endometrial Dedifferentiated Carcinoma|Endometrial Mucinous Adenocarcinoma|Endometrial Serous Adenocarcinoma|Malignant Uterine Neoplasm|Uterine Corpus Carcinosarcoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Liquid Biopsy|OTHER: Pap Smear
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of a Sub-epitheilal Transform™ Corneal Allograft (TCA) for Presbyopia Correction
Status: WITHDRAWN
Conditions: Presbyopia|Refractive Errors
Interventions: OTHER: Sub-epitheilal TCA Inlay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of an Opioid-free Postoperative Pain Management Strategy Versus a Conventional Opioid-based Strategy Following Video-assisted Thoracoscopic Lobectomy
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain
Interventions: DRUG: Ropivacaine|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Energy Expenditure, Sleep and Macronutrients
Status: UNKNOWN
Conditions: Obesity|Overweight|Overnutrition|Nutrition Disorders|Body Weight|Signs and Symptoms
Interventions: DIETARY_SUPPLEMENT: Differences in protein content of meals|DIETARY_SUPPLEMENT: Differences in protein content of meals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Clinical Study on Bortezomib for the Treatment of Refractory Rheumatoid Arthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of ADT and SBRT Versus SBRT for Intermediate Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Degarelix|RADIATION: stereotactic body radiosurgery (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Patient Ability to Understand and Utilize Complex Information Concerning Medication Self-management
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BEHAVIORAL: Medication Guides|BEHAVIORAL: SMART Program|BEHAVIORAL: Drug Facts Boxes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Levothyroxine on Arterial Stiffness and Lipid Profile in Patients With Subclinical Hypothyroidism
Status: COMPLETED
Conditions: Subclinical Hypothyroidism
Interventions: DRUG: Levothyroxine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Safety Study of the Combination of Panitumumab, Irinotecan and Everolimus in the Treatment of Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Carcinoma|Colorectal Tumors|Neoplasms, Colorectal
Interventions: DRUG: Panitumumab|DRUG: Irinotecan|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant IP-001 Treatment for HCC Patients Following Surgical Resection and Ablation or Ablation Alone
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: 1.0% IP-001 for injection|PROCEDURE: Surgical Resection and Local Ablation|PROCEDURE: Local Ablation Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Use of Intraumbilical Vein Oxytocin Injection in The Management of Third Stage of Labor
Status: UNKNOWN
Conditions: Postpartum Hemorrhage
Interventions: DRUG: oxytocin|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: FR901228 in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: DS Stage II Plasma Cell Myeloma|DS Stage III Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: DRUG: Romidepsin|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous CD19 CAR T Cells in Relapsed or Refractory B-cell Lymphoma
Status: UNKNOWN
Conditions: B-cell Lymphoma
Interventions: BIOLOGICAL: autologous anti-CD19 CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Knee Genicular Nerve Ablation by Thermal Radiofrequency vs Thermal Radiofrequency Plus Alcohol Neurolysis
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: genicular nerve ablation by thermal radiofrequency|PROCEDURE: genicular nerve ablation by thermal radiofrequency plus alcohol neurolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Wound Vac Polypropylene Suture Pilot Study
Status: COMPLETED
Conditions: Wound Vac|Suture
Interventions: OTHER: Polypropylene Suture Right Side|OTHER: Polypropylene Suture Left Side
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bortezomib Plus Gemcitabine and Carboplatin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Malignant Pleural Effusion|Recurrent Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: carboplatin|DRUG: bortezomib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Cuff Pressure Between a Taper-guard Cuffed Tube and a Cylindrical-shaped Cuffed Tube
Status: COMPLETED
Conditions: Cuff Pressure
Interventions: DEVICE: Taper guard tube|DEVICE: Cylindrical tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Active-Controlled Early Phase Study of MK-8189 in Adults With Schizophrenia (MK-8189-005)
Status: COMPLETED
Conditions: Schizophrenia, Acute Episode
Interventions: DRUG: MK-8189|DRUG: Risperidone|DRUG: Placebo matching MK-8189|DRUG: Placebo matching risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Placebo-controlled Multicenter Trial to Evaluate the Efficacy and Safety of JTR-161, Allogeneic Human Dental Pulp Stem Cell, in Patients With Acute Ischemic stRoke (J-REPAIR)
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: BIOLOGICAL: JTR-161|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Tiotropium 5 µg/Day Delivered Via the Respimat® Inhaler Over 48 Weeks in Patients With Severe Persistent Asthma on Top of Usual Care (Study I)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: tiotropium 5mcg/day|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Spinal Cord Stimulation in Healthy Adults
Status: NOT_YET_RECRUITING
Conditions: Healthy Adults
Interventions: DEVICE: Spinal motor evoked responses (sMERs)|DEVICE: Continuous stimulation tolerance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Comparative Study of the Analgesic Effect of Spinal Anesthesia or Infiltration Anesthesia for Hemorrhoidectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Local Infiltration|PROCEDURE: Subarachnoidal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dry Needling Versus Magnesium Sulphate Iontophoresis in Subjects With Chronic Mechanical Neck Pain
Status: COMPLETED
Conditions: Chronic Pain
Interventions: OTHER: dry needling|OTHER: magnesium sulphate iontophoresis|OTHER: stretching exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Surgical Resection and Intraoperative Cesium-131 Brachytherapy for Head and Neck Cancer
Status: COMPLETED
Conditions: Recurrent Head and Neck Carcinoma
Interventions: RADIATION: Brachytherapy|DRUG: Cesium-131|PROCEDURE: Conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Three Dimensional Correction During in Bracing in Adolescent Idiopathic Scoliosis
Status: RECRUITING
Conditions: Adolescent Idiopathic Scoliosis
Interventions: COMBINATION_PRODUCT: RCO group|DEVICE: TLSO group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Efficacy and Safety of Levopront® 30 mg/5 ml in Patients With Dry Cough
Status: COMPLETED
Conditions: Cough
Interventions: DRUG: Levopront® syrup 30 mg/5 ml|DRUG: Libexin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Establishing the Clinical Utility of First StepDx PLUS and NextStepDx PLUS Study
Status: COMPLETED
Conditions: Intellectual Disability|Developmental Delay
Interventions: OTHER: FirstStepDX PLUS and NextStepDX PLUS Webinar|OTHER: FirstStepDX PLUS and NextStepDX PLUS Test Results
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Randomized Comparison of Radiation Exposure in Coronary Angiography Between Right Conventional and Left Distal Radial Artery Approach
Status: UNKNOWN
Conditions: Radiation Exposure|Vascular Access Complication|Radial Artery Injury
Interventions: PROCEDURE: artery puncture and coronary angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study HZA106827: Efficacy/Safety Study of Fluticasone Furoate/Vilanterol (GW642444) in Adult and Adolescent Asthmatics
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone furoate/Vilanterol Inhalation Powder|DRUG: Fluticasone Furoate Inhalation Powder|DRUG: Placebo Inhaltion Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cap+Bev vs Cap+Iri+Bev 1st-line Therapy in mCRC
Status: UNKNOWN
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Capecitabine|DRUG: Bevacizumab|DRUG: Capecitabine|DRUG: Irinotecan|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Folic Acid-Tubulysin Conjugate EC1456 In Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors|Non Small Cell Lung Carcinoma
Interventions: DRUG: EC1456 and EC20
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Modified Banxia Xiexin Decoction Treatment on Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer (Diagnosis)
Interventions: DRUG: Modified Banxia Xiexin Decoction|DRUG: combination chemotherapy with Placebo granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IncobotulinumtoxinA (Xeomin) for Upper Limb Spasticity
Status: COMPLETED
Conditions: Upper Limb Spasticity
Interventions: DRUG: incobotulinumtoxinA (Xeomin, also known as "NT 201" or "Botulinum toxin type A (150 kD), free from complexing proteins")
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Atelocollagen in the Management of Chronic Non-specific Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DEVICE: atelocollagen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of SOF/VEL/VOX FDC for 8 Weeks and SOF/VEL for 12 Weeks in Adults Chronic Genotype 3 HCV Infection and Cirrhosis
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: SOF/VEL/VOX|DRUG: SOF/VEL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laryngectomy Education
Status: COMPLETED
Conditions: Total Laryngectomy
Interventions: OTHER: Demographics and Health History Questionnaire|OTHER: Pre-Class Laryngectomy Survey|BEHAVIORAL: Counseling session with speech pathologist|BEHAVIORAL: Total Laryngectomy Preoperative Education Class|OTHER: Day of Hospital Discharge Laryngectomy Survey|OTHER: Day of Discharge Practicum|OTHER: Laryngectomy Education Study Exit Survey
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination of Zanubrutinib, Rituximab and Venetoclax in Patients With Previously Untreated Follicular Lymphoma
Status: RECRUITING
Conditions: Ann Arbor Stage II Follicular Lymphoma|Grade 1 Follicular Lymphoma|Ann Arbor Stage III Follicular Lymphoma|Ann Arbor Stage IV Follicular Lymphoma|Grade 2 Follicular Lymphoma|Grade 3a Follicular Lymphoma
Interventions: DRUG: Zanubrutinib|BIOLOGICAL: Rituximab|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thalidomide in Treating Patients With Metastatic Neuroendocrine Tumors
Status: COMPLETED
Conditions: Gastrointestinal Carcinoid Tumor|Islet Cell Tumor|Lung Cancer|Neoplastic Syndrome
Interventions: DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Feasibility and Effectiveness of Inotuzumab Ozogamicin in B-Cell Acute Lymphoblastic Leukemia
Status: UNKNOWN
Conditions: Acute Lymphoid Leukemia
Interventions: DRUG: Inotuzumab Ozogamicin (IO)|DRUG: Inotuzumab Ozogamicin (IO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy of a Micro Coring Device for the Treatment of Scars of the Cytrellis Micro-Coring Device for the Treatment of Scars
Status: UNKNOWN
Conditions: Scars
Interventions: DEVICE: MCD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melphalan and Amifostine Followed By One or Two Autologous or Syngeneic Stem Cell Transplants and Maintenance Therapy in Treating Patients With Stage II-III Multiple Myeloma
Status: COMPLETED
Conditions: Refractory Multiple Myeloma|Stage II Multiple Myeloma|Stage III Multiple Myeloma
Interventions: DRUG: melphalan|DRUG: amifostine trihydrate|PROCEDURE: peripheral blood stem cell transplantation|GENETIC: fluorescence in situ hybridization|PROCEDURE: bone marrow ablation with stem cell support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Treatment Efficacy and Comfort of a Modified Positive Airway Pressure Device to Treat Obstructive Sleep Apnea.
Status: COMPLETED
Conditions: Obstructive Sleep Apnea (OSA)
Interventions: DEVICE: PAP device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of IMC-A12 in Participants With Tumors Who No Longer Respond to Treatment or For Whom No Treatment is Available
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: BIOLOGICAL: IMC-A12|BIOLOGICAL: IMC-A12|BIOLOGICAL: IMC-A12|BIOLOGICAL: IMC-A12|BIOLOGICAL: IMC-A12|BIOLOGICAL: IMC-A12
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization of MDR-TB Treatment Regimen Based on the Molecular Drug Susceptibility Results of Pyrazinamide
Status: UNKNOWN
Conditions: Multidrug Resistant Tuberculosis
Interventions: DRUG: Pyrazinamide containing regimen|DRUG: Regimen without Pyrazinamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph. I Temozolomide + O6-BG + Irinotecan in Treatment of Pts w Recurrent / Progressive Cerebral Anaplastic Gliomas
Status: COMPLETED
Conditions: Glioblastoma|Gliosarcoma
Interventions: DRUG: Temodar, O6-BG, and Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-center 12-week Study of HMS5552 in T2DM
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: HMS5552|DRUG: HMS5552|DRUG: HMS5552|DRUG: HMS5552|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Preconditioning and Postoperative Myocardial Ischemia
Status: COMPLETED
Conditions: Myocardial Ischemia|Inflammatory Response
Interventions: PROCEDURE: Remote ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Control Trial of Shang Ring Versus Forceps-guided Adult Male Circumcision in Southwestern Uganda.
Status: COMPLETED
Conditions: HIV
Interventions: PROCEDURE: Shang Ring Guided Circumcision|PROCEDURE: Forceps Guided Circumcision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Between Coartem® and Nevirapine, Efavirenz or Rifampicin in HIV Positive Ugandan Patients
Status: UNKNOWN
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: Lumefantrine-artemether and nevirapine|DRUG: lumefantrine-artemether and efavirenz|DRUG: Lumefantrine-artemether and rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atomoxetine in Veterans With Comorbid ADHD/PTSD
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder|Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Atomoxetine 80 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating and Comparing Two Surgical Methods for Treatment of Early Stage Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Breast Cancer|Breast Tumors|Cancer of Breast|Cancer of the Breast|Human Mammary Carcinoma|Neoplasms, Breast
Interventions: PROCEDURE: Remove tumor only|PROCEDURE: Removal of tumor and tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous EEG Randomized Trial in Adults
Status: COMPLETED
Conditions: EEG With Periodic Abnormalities|EEG With Abnormally Slow Frequencies|Coma|Outcome, Fatal
Interventions: DIAGNOSTIC_TEST: continuous EEG (cEEG)|DIAGNOSTIC_TEST: routine EEG (rEEG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Applicability of PBS® CIMMO Cement in Pulpotomies
Status: COMPLETED
Conditions: Pulpotomy
Interventions: DEVICE: formocresol and zinc oxide.|DEVICE: PBS CIMMO cement.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anlotinib Combined With Doxorubicin and Radiotherapy as Neoadjuvant Treatment for Soft Tissue Sarcoma
Status: RECRUITING
Conditions: Soft Tissue Sarcoma|Doxorubicin|Radiotherapy
Interventions: DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Plant-based Diets (Vegetarian and Vegan) on Endothelial Function and Atherogenic Parameters
Status: UNKNOWN
Conditions: Other Endothelial Dystrophy
Interventions: DEVICE: Endo-pat 2000|DEVICE: carotid intima media thickness Ultrasound|DEVICE: Dexa- Bone densitometer & Bone ultrasonometer System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety Study on Agilis NxT Introducer in AF Patients
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Left atrial catheter ablation guided by introducer using Agilis sheeth|PROCEDURE: Left atrial catheter ablation guided by introducer using Non-steerable sheeth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prognosticating Outcomes and Nudging Decisions With Electronic Records in the ICU Trial
Status: COMPLETED
Conditions: Critical Illness
Interventions: BEHAVIORAL: EHR-Based Intervention A|BEHAVIORAL: EHR-Based Intervention B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Psychological, Psychophysical and Epigenetic Determinants of Chronic Pain After Cytoreductive - Hyperthermic Intraoperative Chemotherapy
Status: COMPLETED
Conditions: Appendix Carcinoma|Carcinomatosis|Colorectal Carcinoma|Gastric Carcinoma|Malignant Peritoneal Neoplasm|Malignant Solid Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Pain Assessment|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Vaginal Microbiome on Vaginal Absorption of Exogenous Progesterone: a Pilot Study.
Status: COMPLETED
Conditions: Infertility, Female
Interventions: DIAGNOSTIC_TEST: MICROBIOME GENETIC ANALYSIS|DIAGNOSTIC_TEST: VAGINAL PH VALUE|DIAGNOSTIC_TEST: SERUM PROGESTERONE LEVELS|DIAGNOSTIC_TEST: SERUM OESTRADIOL LEVELS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study on the Effectiveness and Safety of OPTILENE® SILVER MESH ELASTIC in Prevention of Surgical Site Infection (SSI) and Incisional Hernia (IH)
Status: NOT_YET_RECRUITING
Conditions: Abdominal Aortic Aneurysm|Morbid Obesity
Interventions: DEVICE: Prophylactic mesh
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multi-CAR-T Cells Targeting B Cell Lymphomas
Status: UNKNOWN
Conditions: B Cell Lymphoma (BCL)
Interventions: BIOLOGICAL: 4SCAR19 and 4SCAR20/22/70/PSMA/13/79b/GD2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aromatherapy on Pain and Anxiety of the Patients Undergoing Prostate Biopsy
Status: COMPLETED
Conditions: Aromatherapy|Prostate Cancer|Anxiety
Interventions: OTHER: Aromatherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hyaluronic Acid and Octenidine Gel as an Adjunct to Non-surgical Periodontal Treatment
Status: NOT_YET_RECRUITING
Conditions: Periodontitis|Wound Heal|Periodontal Pocket|Periodontal Inflammation|Periodontal Attachment Loss
Interventions: COMBINATION_PRODUCT: Hyaluronic Acid (HA) and Octenidine gel|PROCEDURE: Non-surgical periodontal treatment (NSPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Rituximab in Children and Adolescents With Chronic Idiopathic Thrombocytopenic Purpura (ITP)
Status: COMPLETED
Conditions: Idiopathic Thrombocytopenic Purpura (ITP)|Immune Thrombocytopenic Purpura (ITP)
Interventions: DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatitis B in Cystic Fibrosis and Latent Tuberculosis Respectively
Status: WITHDRAWN
Conditions: Cystic Fibrosis|Hepatitis A|Hepatitis B|Tuberculosis
Interventions: BIOLOGICAL: Vaccination with vaccine against hepatitis A and B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Swiss Intravenous and Intra-arterial Thrombolysis for Treatment of Acute Ischemic Stroke Registry
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: PROCEDURE: Intravenous Thrombolysis|PROCEDURE: Intraarterial Thrombolysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Posiformin 2 % Eye Ointment in the Treatment of Blepharitis
Status: COMPLETED
Conditions: Blepharitis|Signs and Symptoms
Interventions: DRUG: Posiformin 2 %, bibrocathol|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of NGX-1998 for the Treatment of Postherpetic Neuralgia
Status: COMPLETED
Conditions: Postherpetic Neuralgia|Pain
Interventions: DRUG: NGX-1998|DRUG: Placebo Liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of the Zenflow Spring System
Status: ACTIVE_NOT_RECRUITING
Conditions: BPH (Benign Prostatic Hyperplasia)|Lower Urinary Tract Symptoms (LUTS)
Interventions: DEVICE: Zenflow Spring System|DEVICE: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Optimizing Treatment of Peginterferon Alpha in Chronic Hepatitis B Patients With Low Level HBsAg
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Peginterferon Alfa|DRUG: Nucleoside Analog (Substance)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastric Emptying After Infracolic or Supracolic Gastrojejunostomy Following Pancreaticoduodenectomy
Status: COMPLETED
Conditions: Postprocedural Gastric Stasis
Interventions: PROCEDURE: Infracolic gastrojejunal anastamosis|PROCEDURE: Supracolic gastrojejunal anastamosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multicomponent Strategy to Implement a Clinical Practice Guideline and Improve Health Outcomes in People With SLE
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BEHAVIORAL: Multicomponent intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Randomized Clinical Trial of Treatment for Temporomandibular Joint (TMJ) Disc Displacement
Status: COMPLETED
Conditions: Herniated Disk|Temporomandibular Disorders
Interventions: BEHAVIORAL: splint and joint mobilization self exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Breaking up Prolonged Sitting on Metabolic Flexibility
Status: COMPLETED
Conditions: Health Behavior
Interventions: BEHAVIORAL: Uninterrupted sitting|BEHAVIORAL: Sitting + 1 bout of activity|BEHAVIORAL: Sitting + microbursts of activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Unilateral or Bilateral Fixation in the Treatment of LFS
Status: COMPLETED
Conditions: Lumbar Foraminal Stenosis
Interventions: PROCEDURE: TLIF and unilateral pedicle screw fixation|PROCEDURE: TLIF and bilateral pedicle screw fixation|DEVICE: Pedicle screw and cage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of VVZ-149 Injections for the Treatment of Post-Operative Pain Following Abdominoplasty
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: VVZ-149 Injections|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vacuum Assisted Wound Closure and Permanent On-lay Mesh-mediated Fascial Traction in Patients With Open Abdomen
Status: NOT_YET_RECRUITING
Conditions: Open Abdomen|Temporary Abdominal Closure|Incisional Hernia
Interventions: PROCEDURE: Vacuum Assisted Wound Closure and Permanent On-lay Mesh-mediated fascial traction (VAWCPOM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VNP40101M and Cytarabine in Treating Patients With Hematologic Malignancies
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: cytarabine|DRUG: laromustine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Utility of Clinical Balance Measures in Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury|Acquired Brain Injury|Accidental Falls
Interventions: OTHER: Functional Gait Assessment|OTHER: mini-Balance Evaluation Systems Test|OTHER: Berg Balance Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vaccination Efficacy With Metformin in Older Adults
Status: COMPLETED
Conditions: Aging|Age-Related Immunodeficiency|Vaccine Response Impaired
Interventions: DRUG: Metformin Hydrochloride Extended-Release Tablets|BIOLOGICAL: Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE