pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Efficacy and Palatability of Developed Polyethylene Glycol-based Formula for Children With Functional Constipation
Status: NOT_YET_RECRUITING
Conditions: Functional Constipation
Interventions: DRUG: Local PEG4000|DRUG: Commercial PEG4000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Induced Physiological Ketosis in Asthenia and\or Decreased Tolerance to Physical and\or Mental Exertion
Status: NOT_YET_RECRUITING
Conditions: Patient Activation
Interventions: DIETARY_SUPPLEMENT: PanTrek
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Teprotumumab (RV 001) Treatment in Patients With Active Thyroid Eye Disease
Status: COMPLETED
Conditions: Thyroid Associated Ophthalmopathies|Thyroid-Associated Ophthalmopathy
Interventions: DRUG: teprotumumab|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Supplementing Intracytoplasmic Sperm Injection Handling Medium With Latrunculin B ( ICSI-LB)
Status: COMPLETED
Conditions: Infertility
Interventions: OTHER: Medium Supplemented with Latrunculin B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Carnosine and Cognitive Training in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: L-Carnosine|DRUG: Placebo|BEHAVIORAL: Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical Trial of 68Ga-NOTA-SNA002
Status: RECRUITING
Conditions: Solid Tumor|Positron-Emission Tomography(PET)
Interventions: DRUG: 68Ga-NOTA-SNA002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of AP Collagen Peptide on the Skin
Status: COMPLETED
Conditions: Dry Skin
Interventions: DIETARY_SUPPLEMENT: AP collagen peptide|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acupuncture for Aromatase Inhibitor Induced Joint Pain
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: Acupuncture|PROCEDURE: Sham Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transcranial Direct Current Stimulation (tDCS) and Task-Specific Practice for Post-stroke Neglect
Status: TERMINATED
Conditions: Stroke|Hemispatial Neglect
Interventions: DEVICE: tDCS|DEVICE: sham tDCS|BEHAVIORAL: Repetitive task-specific practice (RTP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of ARDS With Sivelestat Sodium
Status: UNKNOWN
Conditions: Acute Respiratory Distress Syndrome
Interventions: DRUG: Sivelestat sodium|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cultivated Autologous Oral Mucosal Epithelial Transplantation
Status: RECRUITING
Conditions: Limbal Stem Cell Deficiency
Interventions: BIOLOGICAL: Cultivated oral mucosal epithelial cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lavage of the Uterine Cavity for the Diagnosis of Ovarian and Tubal Carcinoma and Their Premalignant Changes.
Status: COMPLETED
Conditions: Ovarian Epithelial Cancer
Interventions: PROCEDURE: Lavage of the Cavum uteri and proximal fallopian tubes|PROCEDURE: Liquid-PAP smear
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy-Safety-Immunogenicity Study of CBT124&EU-sourced Avastin® in Stage 4 NSCLC
Status: UNKNOWN
Conditions: Non-Small Cell Lung Carcinoma
Interventions: BIOLOGICAL: CBT124|BIOLOGICAL: EU-sourced Avastin®|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metoclopramide vs Placebo for Prevention of Pneumonia in Acute Stroke
Status: COMPLETED
Conditions: Acute Stroke|Aspiration Pneumonia
Interventions: DRUG: Metoclopramide 10mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hypofractionated Image-Guided Radiation Therapy (IGRT) in Patients With Stage II-III Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: RADIATION: Radiation Therapy|RADIATION: Conventional radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interactions Between Cannabinoids and Cytochrome P450-Metabolized Drugs
Status: COMPLETED
Conditions: Drug-Interactions
Interventions: DRUG: Inje cocktail|DRUG: THC Cannabis extract|DRUG: THC/CBD Cannabis Extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Investigate the Safety, Tolerability, Pharmacokinetics of Single and Multiple Doses of Hepenofovir Fumarate Tablets in Healthy Volunteers.
Status: UNKNOWN
Conditions: Chronic Hepatitis b
Interventions: DRUG: Hepenofovir Fumarate Tablets Single Dose|DRUG: Placebo|DRUG: Hepenofovir Fumarate Tablets Dose4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Tumor Tissue Samples From Patients With Peripheral T-cell Lymphoma or Natural Killer Cell Neoplasms
Status: COMPLETED
Conditions: Lymphoma
Interventions: GENETIC: DNA analysis|GENETIC: cytogenetic analysis|GENETIC: gene mapping|GENETIC: mutation analysis|GENETIC: polymerase chain reaction|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety Study of Combigan and 0.5% Timoptic in Normal Tension Glaucoma
Status: UNKNOWN
Conditions: Normal Tension Glaucoma
Interventions: DRUG: Brimonidine/Timolol mixed combination|DRUG: Timolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recreational Futsal for Controlled Hypertension
Status: COMPLETED
Conditions: Hypertension,Essential|Hypertension|Blood Pressure Disorders|Blood Pressure
Interventions: OTHER: Recreational Futsal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Physostigmine on Cognitive Functioning in the Immediate Period After Sedation for Colonoscopy
Status: UNKNOWN
Conditions: Cognitive Dysfunction
Interventions: DRUG: Physostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Colchicine Randomized Double-Blind Controlled Crossover Study in Behcet's Disease
Status: COMPLETED
Conditions: Behcet's Syndrome
Interventions: DRUG: Colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Recombinant Factor XIII (rFXIII) in Healthy Japanese Volunteers
Status: COMPLETED
Conditions: Acquired Bleeding Disorder|Cardiac Surgery Requiring Cardiopulmonary Bypass|Healthy
Interventions: DRUG: catridecacog|DRUG: placebo|DRUG: catridecacog|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study in Healthy Subjects to Determine the Effect of Relacorilant on Exposure to Probe Substrates for Cytochrome P450s
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Midazolam hydrochloride|DRUG: Metoprolol tartrate|DRUG: Pioglitazone hydrochloride|DRUG: Tolbutamide|DRUG: Omeprazole|DRUG: Relacorilant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Global Study of the Efficacy and Safety of Midostaurin + Chemotherapy in Newly Diagnosed Patients With FLT3 Mutation Negative (FLT3-MN) Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: Midostaurin|DRUG: Placebo|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Antibiotics in Cystectomy With Diversion
Status: RECRUITING
Conditions: Muscle-Invasive Bladder Carcinoma|Radical Cystectomy|Ileal Conduit|Neobladder Diversion
Interventions: DRUG: Prophylactic antibiotics postoperatively.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Randomized Phase III Study Comparing Second-line Treatment With Chemotherapy Associated or Not to Erlotinib in NSCLC Patients With Secondary Resistance to TKI-EGFR
Status: TERMINATED
Conditions: NSCLC Patients With EGFR Activating Mutation
Interventions: DRUG: ERLOTINIB WITH CHEMOTHERAPY|DRUG: CHEMOTHERAPY ONLY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Structural and Functional Grey and White Matter Changes in Patients With Pain Disorders
Status: RECRUITING
Conditions: Central Post-stroke Pain
Interventions: DIAGNOSTIC_TEST: Quantitative sensory testing (QST)|DIAGNOSTIC_TEST: Magnetic resonance imaging (MRI)|OTHER: Clinical interview/exam|OTHER: Follow-up interview
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Effects of Ketoconazole Taken Orally Has on the PK Profiles of a Dose of GSK189075 in Healthy Volunteers
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Diabetes Mellitus, Type 2
Interventions: DRUG: ketoconazole|DRUG: GSK189075
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: β-adrenergic Blocker and a COX2 Inhibitor for Prevention of Colorectal Cancer Recurrence
Status: UNKNOWN
Conditions: Colorectal Neoplasms
Interventions: DRUG: Propranolol and Etodolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Probiotic Supplementation in Preventing Treatment-Related Diarrhea in Patients With Cancer Undergoing Chemotherapy
Status: WITHDRAWN
Conditions: Diarrhea|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DIETARY_SUPPLEMENT: Lactobacillus plantarum strain 299v|DIETARY_SUPPLEMENT: Lactobacillus acidophilus probiotic|DIETARY_SUPPLEMENT: placebo|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment|DIETARY_SUPPLEMENT: Bifidobacterium lactis probiotic supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Myofascial Trigger Point Release and Paced Breathing Training for Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: OTHER: Core stabilization exercises|OTHER: Core stabilization exercises and paced breathing training|OTHER: Myofascial trigger point release|OTHER: Myofascial trigger point release and paced breathing training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Alone or Sequentially Following Single Fraction Non-ablative Radiation to One of the Target Lesions, in Previously Treated Patients With Stage IV NSCLC
Status: COMPLETED
Conditions: Stage IV Non-Small Cell Lung Cancer
Interventions: DRUG: Pembrolizumab|RADIATION: Single Fraction Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BCI-assisted MI Intervention in Subacute Stroke
Status: COMPLETED
Conditions: Stroke|Motor Disorders
Interventions: OTHER: EEG-based BCI system for (hand) Motor Imagery training|OTHER: Motor Imagery training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Progesterone for Perimenopausal Night Sweats
Status: COMPLETED
Conditions: Hot Flushes|Night Sweats
Interventions: DRUG: Oral micronized progesterone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tissue Doppler Imaging (TDI) Versus Electrocardiography (ECG) Interventricular Pacing Delay Optimization in Cardiac Resynchronization Therapy (CRT)
Status: COMPLETED
Conditions: Heart Failure|Cardiac Resynchronization Therapy
Interventions: DEVICE: Interventricular pacing delay optimization by using Tissue Doppler-derived displacement curves|DEVICE: Electrocardiographic optimization of the interventricular pacing delay according to QRS width
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alveolar Microperforation for Inflammation-Enhanced Tooth Movement During Orthodontic Treatment
Status: COMPLETED
Conditions: Malocclusion
Interventions: DEVICE: Micro-osteoperforation|DRUG: Anesthestic|OTHER: Chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Risedronate, Cholecalciferol Combination Tablet in Patients With Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Risedronate/Cholecalciferol combination|DRUG: Risedronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EA Treatment With Different Waveform for Subacute BP:Study Protocol for a Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Bell Palsy
Interventions: OTHER: low-frequency continuous wave EA|OTHER: discontinuous wave EA|OTHER: dilatational wave EA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Radiation Plus TACE and Lenvatinib in Advanced HCC With PVTT
Status: WITHDRAWN
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: Lenvatinib|PROCEDURE: TACE|RADIATION: External beam radiation (RT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Vein (PV) Isolation Versus Box Isolation for the Treatment of Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Radiofrequency Ablation
Interventions: PROCEDURE: usual PV ablation|PROCEDURE: Box isolation of pulmonary veins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Oral Nutritional Supplements on the Nutritional Status of Elderly Patients
Status: COMPLETED
Conditions: Nutrition Disorders in Old Age|Nutritional Supplement Toxicity|Elderly Infection
Interventions: DIETARY_SUPPLEMENT: Nutridrink Multi Fibre
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of hUC-MSC Product (BX-U001) for the Treatment of COVID-19 With ARDS
Status: NOT_YET_RECRUITING
Conditions: COVID-19|ARDS|Acute Respiratory Distress Syndrome
Interventions: BIOLOGICAL: Human umbilical cord mesenchymal stem cells + best supportive care|OTHER: Placebo control + best supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Dry Needling as a Treatment of Shoulder Myofascial Pain Syndrome in Spinal Cord Injury Patients
Status: UNKNOWN
Conditions: Spinal Cord Injuries|Myofascial Pain Syndrome|Shoulder Pain|Puncture
Interventions: PROCEDURE: Dry needling in infraspinatus muscle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Coconut Nourish and Queen Garnet Plum to Improve Health in an Elderly Population
Status: TERMINATED
Conditions: Healthy Ageing
Interventions: OTHER: Treatment cookies|OTHER: Control cookies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Product Performance of a New Silicone Hydrogel Contact Lens
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: kalifilcon A|DEVICE: delefilcon A|DEVICE: senofilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Concept for Continuous Peripheral Nerve Block - Sciatic Nerve
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: lidocainhydrochlorid|DRUG: Isotonic Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study to Examine the Safety and Toleration of PEP005 Topical Gel in Patients With Actinic Keratoses on the Top of the Hand
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: PEP005 gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Caffeinated and Decaffeinated Coffee on Body Weight and Glucose Tolerance
Status: COMPLETED
Conditions: Overweight
Interventions: DIETARY_SUPPLEMENT: Decaffeinated coffee|DIETARY_SUPPLEMENT: Caffeinated coffee|DIETARY_SUPPLEMENT: No coffee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Dipeptidyl-4 Inhibitors in Reducing Stroke Severity, From HIRA Database
Status: NOT_YET_RECRUITING
Conditions: Cerebral Infarction|Infarction, Brain|Dipeptidyl-Peptidase IV Inhibitors
Interventions: DRUG: Dipeptidyl peptidase-4 inhibitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Resistance Training and Milk Supplementation
Status: COMPLETED
Conditions: Muscular Hypertrophy
Interventions: DIETARY_SUPPLEMENT: high protein milk|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ultrasound Assessment of Gastric Residual Volume in Children Scheduled for Elective Surgery After Clear Fluids Fasting for One Versus Two Hours: a Comparative Study
Status: COMPLETED
Conditions: Gastric Emptying
Interventions: DEVICE: gastric ultrasound|OTHER: the clear fluid intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Collect Blood Biomarker Samples From Participants With Chronic Hepatitis B (CHB) Who Received Treatment With Pegasys (Peginterferon Alfa-2a) ± Nucleoside/Nucleotide Analogue
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Peg-IFN alfa-2a
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Antioxidants on the Immune Response and Wound Healing in Critically Ill Patients
Status: COMPLETED
Conditions: Pressure Sores|Intensive Care
Interventions: DIETARY_SUPPLEMENT: Eicosapentanoic acid, docosahexaenoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of TLL-018 in Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: TLL-018|DRUG: TLL-018|DRUG: TLL-018|DRUG: Tofacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Pharmacodynamics of 3 Dosages of Estriol After Continuous Vaginal Administration for 21 Days
Status: COMPLETED
Conditions: Menopause
Interventions: DRUG: Estriol 0.125 mg/day|DRUG: Estriol 0.250 mg/day|DRUG: Estriol 0.500 mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Linked Color Imaging/Magnifying Blue Laser Imaging vs. White Light for Adenomas and Serrated Lesions in Proximal Colon
Status: UNKNOWN
Conditions: Colon Cancer
Interventions: DEVICE: LCI/BLI then white endoscopy|DEVICE: White endoscopy and then LCI/BLI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study
Status: RECRUITING
Conditions: Pleuropulmonary Blastoma|Cystic Nephroma|Ovarian Sertoli-Leydig Cell Tumors|Ocular Medulloepithelioma|Nasal Chondromesenchymal Hamartoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Quetiapine and Trazodone Treatment for Insomnia in Dually Diagnosed Veterans
Status: TERMINATED
Conditions: Insomnia|Mental Health Disorder|Substance Use Disorder
Interventions: DRUG: Quetiapine|DRUG: Trazodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulsed Electromagnetic Field Versus Treadmill Walking in Peripheral Arterial Disease
Status: UNKNOWN
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: pulsed electromagnetic field|OTHER: treadmill training|DRUG: Medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ketamine/Propofol vs Ketamine Alone for Pediatric Fracture Reduction
Status: COMPLETED
Conditions: Fractures
Interventions: DRUG: Ketamine only|DRUG: Ketamine - Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: French eCLIPs™ Efficacy and Safety Investigation
Status: RECRUITING
Conditions: Intracranial Aneurysm
Interventions: PROCEDURE: Implantation of an eCLIPs™ device|DEVICE: eCLIPs™ Electrolytic Bifurcation Systems
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Symbicort ® on GR in Sputum in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Lung Disease
Interventions: DRUG: Symbicort® total dose 400ug/12ug|DRUG: Symbicort® total dose 800ug/24ug|DRUG: Formoterol 24ug|DRUG: BUD total dose 800ug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Regimen Switch to Dolutegravir + Rilpivirine From Current Antiretroviral Regimen in Human Immunodeficiency Virus Type 1 Infected and Virologically Suppressed Adults (SWORD-2)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: DTG 50 mg|DRUG: RPV 25 mg|DRUG: CAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zoledronate in Preventing Osteoporosis and Bone Fractures in Patients With Locally Advanced Nonmetastatic Prostate Cancer Undergoing Radiation Therapy and Hormone Therapy
Status: COMPLETED
Conditions: Osteoporosis|Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: Calcium|DIETARY_SUPPLEMENT: Zoledronic acid|RADIATION: radiation therapy|DRUG: LHRH|DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Diversity and Inclusion in Research Underpinning Prevention and Therapy Trials
Status: RECRUITING
Conditions: Breast Cancer|Liver Cancer|Prostate Cancer
Interventions: BEHAVIORAL: Clinical trial match-list|BEHAVIORAL: Match-list intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Thyroid Hormone to Induce Non-Insulin Mediated Glucose Disposal in People With Insulin Receptor Mutations
Status: COMPLETED
Conditions: Insulin Resistance|Diabetes Mellitus|Abnormal Glucose Metabolism
Interventions: DRUG: Liothyronine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BP-C1 in Short-term Treatment of Thai Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: BP-C1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TMS in Treatment of Schizophrenia Negative Symptoms
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DEVICE: HR rTMS|DEVICE: sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Varying Bone Marrow-Derived Mesenchymal Stem Cells Concentrations' Impact on Rotator Cuff Repair Outcomes
Status: NOT_YET_RECRUITING
Conditions: Rotator Cuff Tears
Interventions: OTHER: Rotator cuff repair augmented with whole bone marrow|OTHER: Rotator cuff repair augmented with concentrated bone marrow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Initial Attack on Latent Metastasis Using TAS-102 for ct DNA Identified Colorectal Cancer Patients After Curative Resection
Status: RECRUITING
Conditions: Colorectal Neoplasms|Trifluridine and Tipiracil|Circulating Tumor DNA
Interventions: DRUG: trifluridine and tipiracil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single-shot Pectoral Plane(PECs) Block Versus Continuous Local Anaesthetic Infusion Analgesia or Both PECS Block and Local Anaesthetic Infusion After Breast Surgery: A Prospective Randomised, Double-blind Trial
Status: COMPLETED
Conditions: Breast Diseases|Anesthesia|Block
Interventions: PROCEDURE: Pectoral Plane Block|PROCEDURE: Local Anaesthetic Wound Infusion Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Cyclosporine (CsA) Versus Tacrolimus (Tacro) After Campath Induction in Kidney Transplantation
Status: COMPLETED
Conditions: Acute Graft Rejection|Chronic Allograft Nephropathy|Polyomavirus-related Transplant Nephropathy
Interventions: DRUG: cyclosporine or tacrolimus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison Study of Biofoam Porous Metal Versus Allograft to Treat Adult Acquired Flatfoot
Status: WITHDRAWN
Conditions: Adult Acquired Flatfoot
Interventions: DEVICE: Biofoam|OTHER: Iliac Crest Allograft with locked plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Efficacy of Topical BPR277 for the Treatment of Atopic Dermatitis and Netherton Syndrome
Status: COMPLETED
Conditions: Healthy Volunteers|Atopic Dermatitis|Netherton Syndrome
Interventions: DRUG: BPR277 ointment (controlled application)|DRUG: Placebo (Vehicle)|DRUG: BPR277 ointment|DRUG: Placebo (Vehicle)|DRUG: BPR277|DRUG: Placebo (Vehicle)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Dasatinib in Patients With Chronic Myeloid Leukemia
Status: TERMINATED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Dasatinib (Sprycel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ociperlimab Plus Tislelizumab Plus Chemoradiotherapy in Participants With Untreated Limited-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Limited Stage Small Cell Lung Cancer
Interventions: DRUG: Ociperlimab|DRUG: Tislelizumab|DRUG: Concurrent Chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Nexium (Esomeprazole) 40 mg Once Daily in Subjects With Symptoms of Gastroesophageal Reflux Disease (GORD) After Treatment With a Full Dose of Proton Pump Inhibitor (PPI)
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Esomeprazole 40 mg|PROCEDURE: Physical Exam|OTHER: Quality of Life Questionnaires|PROCEDURE: pregnancy test, if applicable
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote and In-person Supervised Exercise in Patients With Knee Osteoarthritis
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: OTHER: Remote supervised exercise group|OTHER: In-person supervised exercise group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of a Curriculum About Professionalism on Stress Response During a Critical Situation
Status: COMPLETED
Conditions: Professional Burnout|Professional Stress|Anesthesia|Medical Education|High Fidelity Simulation|Anxiety State
Interventions: OTHER: Professionalism curriculum
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tailored Medication Management Intervention
Status: COMPLETED
Conditions: Medication Non Adherence|Polypharmacy
Interventions: BEHAVIORAL: Medication Management Remote Intervention|BEHAVIORAL: Waitlist Control|BEHAVIORAL: Medication Management In-Person Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Invirase (Saquinavir)/Ritonavir in HIV-Infected Infants and Children.
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: ritonavir|DRUG: saquinavir [Invirase]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DBRPC Study to Evaluate the Efficacy and Safety of IQP-AE-103 in Overweight and Moderately Obese Subjects
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DIETARY_SUPPLEMENT: IQP-AE-103|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ambulatory Blood Pressure Monitoring (ABPM) Extension Study of Oral Testosterone Undecanoate in Hypogonadal Men
Status: COMPLETED
Conditions: Hypogonadism, Male
Interventions: DRUG: SOV2012-F1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Effectiveness of REAL INTELLIGENCE™ CORI™ in Unicondylar Knee Arthroplasty (UKA) Procedures
Status: RECRUITING
Conditions: Non-inflammatory Degenerative Joint Disease, Including Osteoarthritis|Avascular Necrosis|Requires Correction of Functional Deformity|Requires Treatment of Fractures That Were Unmanageable Using Other Techniques
Interventions: DEVICE: CORI|DEVICE: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FoCo: Evaluating a Training to Increase Attention and Awareness of Healthcare Professionals
Status: COMPLETED
Conditions: Attention|Self-compassion
Interventions: BEHAVIORAL: FoCo|BEHAVIORAL: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Primary Refractory Neuroblastoma in Bone Marrow
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: 3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Lung Small Cell Carcinoma|Metastatic Malignant Solid Neoplasm|Metastatic Neuroendocrine Carcinoma|Metastatic Pancreatic Adenocarcinoma|Stage III Lung Cancer AJCC v8|Stage III Pancreatic Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IV Pancreatic Cancer AJCC v8|Unresectable Lung Small Cell Carcinoma|Unresectable Malignant Solid Neoplasm|Unresectable Neuroendocrine Carcinoma|Unresectable Pancreatic Adenocarcinoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Elimusertib|DRUG: Irinotecan Hydrochloride|PROCEDURE: Magnetic Resonance Imaging|DRUG: Topotecan Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of an Oral Vaccine to Prevent Seasonal Influenza
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: VXA-A1.1 Oral Vaccine|BIOLOGICAL: VXA Placebo Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lidocaine Patch 5% Versus Celecoxib 200 mg in Chronic Axial Low Back Pain
Status: TERMINATED
Conditions: Chronic Low Back Pain
Interventions: DRUG: Lidoderm®|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Suvorexant to Reduce Symptoms of Nicotine Use
Status: RECRUITING
Conditions: Smoking Cessation
Interventions: DRUG: Suvorexant 20 mg|DRUG: Suvorexant 0mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Holofiber Socks and Bedding on Pain and Quality of Sleep in Subjects With Chronic Foot Pain
Status: TERMINATED
Conditions: Diabetic Neuropathy|Arthritis|Peripheral Arterial Disease|Plantar Fasciitis
Interventions: DEVICE: Holofiber fabric|DEVICE: PET fabric
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency in the Female Stress Urinary Incontinence
Status: RECRUITING
Conditions: Urinary Stress Incontinence
Interventions: DEVICE: Radiofrequency|DEVICE: Radiofrequency OFF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Rehabilitation Nursing Consultation for People With Asthma on Symptom Control and Quality of Life
Status: COMPLETED
Conditions: Asthma|Rehabilitation|Breathing, Mouth|Nursing Caries|Adult
Interventions: OTHER: Abdomino-diaphragmatic breathing|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Pelvic Adjuvant Radiation Therapy in Cancers of the Uterus.
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrioid Adenocarcinoma|Serous Carcinoma|Clear Cell Carcinoma|Carcinosarcoma|Dedifferentiated Carcinoma
Interventions: RADIATION: Image-guided adjuvant pelvic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Fludarabine Based Conditioning for Allogeneic Stem Cell Transplantation for Myelofibrosis
Status: COMPLETED
Conditions: Myelofibrosis
Interventions: DRUG: Fludarabine, Melphalan +/- ATG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Intervention of Time-restricted Eating in High-risk Populations of GDM
Status: NOT_YET_RECRUITING
Conditions: Gestational Diabetes Mellitus|Dietary Habits|Lifestyle Intervention|Randomized Controlled Study
Interventions: BEHAVIORAL: Time-limited eating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of the Influence of the Virtual Reality Headset on Pain and Anxiety During Oocyte Retrieval Under Local Anesthesia
Status: RECRUITING
Conditions: Oocyte Retrieval|Local Anaesthesia|Virtual Reality
Interventions: OTHER: VR+
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevalence of Sleep Disordered Breathing in a Lung Cancer Screening Cohort
Status: COMPLETED
Conditions: Sleep Apnea Hypopnea Syndrome|COPD|Emphysema|Lung Cancer
Interventions: OTHER: poligraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial Seizures
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: perampanel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Adrenal Androgens in Normal and Obese Girls After Suppression and Stimulation
Status: ACTIVE_NOT_RECRUITING
Conditions: Hyperandrogenemia|Polycystic Ovary Syndrome|Obesity
Interventions: DRUG: Dexamethasone|DRUG: Cortrosyn
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Non-Specific Endothelin-A Receptor Blockade on Ocular Blood Flow in Patients With Glaucoma
Status: COMPLETED
Conditions: Glaucoma|Blood Flow Velocity
Interventions: DRUG: bosentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Respiratory Variations of the Diameter of Superior Vena Cava for Predicting Fluid Responsiveness After Cardiac Surgery
Status: COMPLETED
Conditions: Transesophageal Echocardiography|Vena Cava Superior
Interventions: OTHER: Trans oesophageal echocardiography|OTHER: Trendelenburg test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nebulized Dexmedetomidine as a Premedication for Gastrointestinal Endoscopy in Pediatric Patients
Status: COMPLETED
Conditions: Pediatric|Sedation
Interventions: OTHER: a routine sedation protocol|DRUG: Nebulized with dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Obstructive Sleep Apnea With Long Range 3D Endoscopic Fourier Domain Optical Coherence Tomography (FDOCT)
Status: WITHDRAWN
Conditions: Sleep Apnea
Interventions: DEVICE: 3D endoscopic Fourier Domain OCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Prosthetic Femoropopliteal Bypass Versus Viabahn Endoprosthesis for Treatment of Symptomatic Femoral Artery Occlusion
Status: COMPLETED
Conditions: Atherosclerosis|Lower Extremity Ischemia|Claudication|Rest Pain
Interventions: PROCEDURE: Femoral-popliteal bypass|PROCEDURE: Stent-graft placement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Administration of Rapidly Generated Multivirus-specific Cytotoxic T-Lymphocytes (VIRAGE)
Status: COMPLETED
Conditions: Adenovirus Infection|Epstein-Barr Virus Infections|Cytomegalovirus Infections|Stem Cell Transplant
Interventions: BIOLOGICAL: Multi-virus Specific T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different End-tidal Carbon-dioxide Levels on Cerebral CO2 Vasoreactivity and the Stiffness of Systemic Arteries During Propofol Anesthesia
Status: COMPLETED
Conditions: Propofol-anaesthesia Via Target-controlled Infusion
Interventions: PROCEDURE: Partial pressure of CO2 at the end of an exhaled breath|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chronic Widespread Pain and White Blood Cell Activation
Status: COMPLETED
Conditions: Widespread Chronic Pain
Interventions: DRUG: Ketotifen Fumarate|DRUG: Placebo|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Indirect vs. Direct Pulp Capping in Deep Carious Mandibular Molars
Status: NOT_YET_RECRUITING
Conditions: Indirect Pulp Capping|Reversible Pulpitis
Interventions: PROCEDURE: INDIRECT AND DIRECT PULP CAPPING AFTER PARTIAL OR COMPLETE CARIES REMOVAL IN DEEPLY CARIOUS MATURE PERMANENT MANDIBULAR MOLARS WITH MODERATE PULPITIS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Iloprost in Subjects With Symptomatic Raynaud's Phenomenon Secondary to Systemic Sclerosis (Phase 2)
Status: COMPLETED
Conditions: Raynaud Phenomenon Secondary to Systemic Sclerosis
Interventions: DRUG: Placebo IV infusion|DRUG: Iloprost Injection, for intravenous use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imatinib and Rituximab in Treating Cutaneous Sclerosis in Patients With Chronic Graft-Versus-Host Disease
Status: COMPLETED
Conditions: Graft Versus Host Disease|Systemic Scleroderma
Interventions: DRUG: imatinib mesylate|BIOLOGICAL: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of a Zoster Vaccine in Healthy Adults >= 40 Years
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: One shot of the zoster vaccine|BIOLOGICAL: One shot of the varicella vaccine|BIOLOGICAL: one shot of placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Two Antiemetic Regimens in Patients Receiving Radiotherapy and Concomitant Weekly Cisplatin
Status: COMPLETED
Conditions: Nausea|Vomiting|Genital Neoplasms, Female
Interventions: DRUG: Fosaprepitant dimeglumine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intraoperative Methadone Administration for Improved Pain Control in Spinal Fusion Patients
Status: TERMINATED
Conditions: Pain, Postoperative
Interventions: DRUG: Methadone Hydrochloride|OTHER: Standard pain regimen|PROCEDURE: Spinal Fusion Surgery|DRUG: Dexamethasone|DRUG: Ketamine|DRUG: Remifentanil|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT