pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Dihydrotestosterone (DHT) on Prostate Tissue [Short Title: DHT-3]
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dihydrotestosterone (DHT) gel (0.7%)|DRUG: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exoskeleton-assisted Upper Limb Rehabilitation After Stroke
Status: COMPLETED
Conditions: Stroke|Upper Extremity Dysfunction
Interventions: DEVICE: Exoskeleton robot for upper extremity|OTHER: Conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short Structured Psychological Intervention for Adults With ADHD - a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: BEHAVIORAL: Short ADHD Intervention|OTHER: Self-help material with limited therapist support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiological Outcomes of Medacta Shoulder System FR
Status: RECRUITING
Conditions: Primary Osteoarthritis|Secondary Osteoarthritis|Rotator Cuff Tear Arthropathy|Rheumatoid Arthritis Shoulder|Avascular Necrosis|Fracture|Revision of Shoulder Arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Eliminating Monitor Overuse Trial (EMO Trial)
Status: RECRUITING
Conditions: Bronchiolitis Acute Viral
Interventions: BEHAVIORAL: Educational Outreach|BEHAVIORAL: Audit & Feedback (unit level)|BEHAVIORAL: Audit & Feedback (real time, individual-level)|BEHAVIORAL: Clinical Pathway Integrated into Electronic Health Record
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Compare Different Intubating Doses of Zemuron in Pediatric and Adolescent Subjects Under General Anesthesia
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Rocuronium bromide (Zemuron)|DRUG: Rocuronium bromide (Zemuron)|DRUG: Rocuronium bromide (Zemuron)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quetiapine for Primary Insomnia Patients : A Randomized Controlled Trial
Status: COMPLETED
Conditions: Primary Insomnia
Interventions: DRUG: Quetiapine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Absorption and Elimination of Radiolabeled Daprodustat
Status: COMPLETED
Conditions: Anaemia
Interventions: DRUG: [14C]-GSK1278863 solution for IV infusion|DRUG: [14C]-GSK1278863 oral solution|DRUG: Daprodustat 6 mg oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring HIFU as a Treatment for Rectal and Other Pelvic Cancers
Status: UNKNOWN
Conditions: Rectal Cancer|Rectal Neoplasms|Pelvic Cancer|Endometrial Cancer|Cervical Cancer
Interventions: DEVICE: High Intensity Focused Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome Measures of Modified Constraint Induced Movement Therapy Versus Dual Task Training on Upper Extremity and Cognitive Functions in Patients With Hemiparesis
Status: COMPLETED
Conditions: Hemiparesis
Interventions: OTHER: Modified Constraint Induced Movement therapy|OTHER: Dual task training in the form of cognitive - motor task|OTHER: Conventional physiotherapy rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Interactive Opioid Risk Education Program (STOMP) for Parents
Status: COMPLETED
Conditions: Pain, Postoperative|Medication Adherence|Opioid Use|Knowledge, Attitudes, Practice|Risk Reduction Behavior
Interventions: BEHAVIORAL: Educational Intervention|BEHAVIORAL: Nudge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Hyperbaric OxygeN Therapy on brEast Cancer Patients With Late Radiation toxicitY - UMBRELLA HONEY Trial
Status: COMPLETED
Conditions: Breast Cancer|Radiation Toxicity
Interventions: DRUG: Hyperbaric oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Computer Interface: Neuroprosthetic Control of a Motorized Exoskeleton
Status: RECRUITING
Conditions: Traumatic Tetraplegia With Cervical Cord Injury
Interventions: DEVICE: Brain-computer interface (BCI) platform including two implanted remotely powered ElectroCorticoGraph (ECoG) recording devices and an exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intercostobrachial Nerve Sparing to Reduce Post-Surgical Pain
Status: UNKNOWN
Conditions: Post-surgical Pain|Pain, Chronic|Intercostal Pain|Breast Cancer
Interventions: OTHER: ICBN preservation surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Application of Indocyanine-Green(ICG) Fluorescence Imaging in Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Indocyanine-Green(ICG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trospium Chloride XR in Obese Female Patients With Overactive Bladder
Status: COMPLETED
Conditions: Obesity|Overactive Bladder|Incontinence
Interventions: DRUG: Trospium Chloride, Extended Release (XR)|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MVA to Improve the Pregnancy Outcome in Aged Infertility Women With Assisted Reproductive Technology
Status: RECRUITING
Conditions: Infertility, Female|IVF|Reproductive Disorder|Oocyte
Interventions: DIETARY_SUPPLEMENT: Mevalproic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Newly Reported (0-90°) Versus (0-30°) Biplanar Fluoroscopic Puncture Technique in PCNL
Status: COMPLETED
Conditions: Nephrolithotomy, Percutaneous|Kidney Stone|PCNL
Interventions: PROCEDURE: 0-30° Biplanar Fluoroscopic Puncture Techniques for Percutaneous Nephrolithotomy|PROCEDURE: New 0-90° Fluoroscopic Puncture Techniques for Percutaneous Nephrolithotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: (GluEsk) Glutamate and Esketamine
Status: NOT_YET_RECRUITING
Conditions: Depression
Interventions: DRUG: Esketamine nasal spray|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Maternal Metabolic and Molecular Changes Induced by Preconception Weight Loss and Their Effects on Birth Outcomes
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity; Familial|Pregnancy Related
Interventions: DIETARY_SUPPLEMENT: Very-low energy Diet (VLED)|OTHER: Standard of care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Shotblocker in Spinal Needle Related Pain
Status: COMPLETED
Conditions: Needle Phobia|Spinal Anesthesia|Pain
Interventions: PROCEDURE: Shotblocker|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Two Skeletally Anchored Force Mechanics for Skeletal Class II Correction in Growing Patients
Status: UNKNOWN
Conditions: Malocclusion
Interventions: PROCEDURE: Miniplates in mandibular symphysis & infrazygomatic|PROCEDURE: Miniplates in external oblique ridge & anterior maxillary region
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability Study and Food Effect Study of TT-00420 (Tinengotinib) Capsule and Tablet Formulations in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TT-00420 Capsule|DRUG: TT-00420 Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Influence of Anesthetic Temperature on Cephalad Sensory Blockade With Spinal Anesthesia
Status: COMPLETED
Conditions: Cesarean Delivery
Interventions: DRUG: bupivacaine/fentanyl/morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Careful Ventilation in Acute Respiratory Distress Syndrome (COVID-19 and Non-COVID-19)
Status: RECRUITING
Conditions: ARDS
Interventions: OTHER: Respiratory Mechanics|OTHER: Standard Ventilation Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Decision-Aid for Renal Therapy Pilot Trial
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic|Kidney Failure, Chronic
Interventions: BEHAVIORAL: DART|BEHAVIORAL: Choosing a Treatment for Kidney Failure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of EPA and Vitamin E on Leptin, Adiponectin and Enzymatic Antioxidants in Type 2 DM
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: EPA, Vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Biodistribution of 11C-PIB PET in Alzheimer's Disease, Frontotemporal Dementia, and Cognitively Normal Elderly
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: RADIATION: 11C-PIB PET Scan|RADIATION: FDG-PET Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)
Status: RECRUITING
Conditions: Neurofibromatosis 1|Plexiform Neurofibromas
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SU5416 and Doxorubicin in Treating Patients With Stage IIIB or Stage IV Inflammatory Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: doxorubicin hydrochloride|DRUG: semaxanib|PROCEDURE: conventional surgery|RADIATION: radiation therapy|DRUG: tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Higher Per Daily Treatment-Dose Radiation Therapy or Standard Per Daily Treatment Radiation Therapy in Treating Patients With Early-Stage Breast Cancer That Was Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: Standard fractionation whole breast irradiation|RADIATION: Hypofractionated whole breast irradiation|RADIATION: Concurrent boost|RADIATION: Sequential boost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of Allogeneic Umbilical Cord Blood-derived Mesenchymal Stem Cell in Patients With RDEB
Status: COMPLETED
Conditions: Recessive Dystrophic Epidermolysis Bullosa
Interventions: DRUG: Human Umbilical Cord Blood-derived Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of LJM716 and Cetuximab in Head and Neck Squamous Cell Carcinoma Patients
Status: WITHDRAWN
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: BIOLOGICAL: LJM716|BIOLOGICAL: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise and Disease Progression in Amyotrophic Lateral Sclerosis Patients
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: OTHER: standard care|OTHER: moderate exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety and Efficacy of AZD5718 in Participants With Proteinuric Chronic Kidney Disease
Status: TERMINATED
Conditions: Chronic Kidney Disease
Interventions: DRUG: AZD5718|DRUG: Dapagliflozin 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FASST - Fetal Alcohol Spectrum Stimulant Trial
Status: RECRUITING
Conditions: Fetal Alcohol Spectrum Disorders
Interventions: DRUG: Methylphenidate Hydrochloride|DRUG: Placebo|DRUG: Methylphenidate hydrochloride|DRUG: Methylphenidate Hydrochloride 18 MG|DRUG: Dexamphetamine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Follow-up Study to Test Long-term Treatment With BI 1015550 in People With Pulmonary Fibrosis Who Took Part in a Previous Study With BI 1015550
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis|Progressive Pulmonary Fibrosis
Interventions: DRUG: BI 1015550
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating Patient Characteristics of Intermediate Stage Hepatocellular Carcinoma Patients Treated With Nexavar and Their Distribution to Different Treatment Groups as Well as Determining Effectiveness and Safety
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comorbidity Management in Rheumatic Disease.
Status: NOT_YET_RECRUITING
Conditions: Rheumatoid Arthritis|Comorbidities and Coexisting Conditions
Interventions: OTHER: Primary Care Rheumatology Family Physician Consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: COVID-19, Patients' Evolution and the Influence of the Pandemic on Health Care and Outcomes in Chronic Diseases
Status: RECRUITING
Conditions: COVID-19 Pandemic|Pulmonary Disease, Chronic Obstructive|Heart Failure, Congestive|Depressive Symptoms
Interventions: OTHER: No interventions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pain and Anxiety Levels of Sleeperone Electronic Anesthesia System in Pediatric Patients
Status: COMPLETED
Conditions: Dental Anxiety|Pain
Interventions: OTHER: Children's Fear Survey Schedule-Dental Subscale (CFSS-DS) scale|OTHER: Face Image Scale (FIS) scoring system|OTHER: Visual Analogue Scale (VAS)|OTHER: pulse rate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Optimal Endotracheal Cuff Pressure During Hospitalization in Intensive Care Units Using AnapnoGuard 100 System
Status: COMPLETED
Conditions: Ventilator Associated Pneumonia
Interventions: DEVICE: AnapnoGuard 100
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Shigella CVD 30000: Study of Responses to Vaccination With Shigella Vaccine
Status: COMPLETED
Conditions: Shigella
Interventions: BIOLOGICAL: SF2a-TT15 Shigella Vaccine|OTHER: Placebo|BIOLOGICAL: S. flexneri 2a strain 2457T Challenge Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ADCC Mediated B-Cell dEpletion and BAFF-R Blockade
Status: ACTIVE_NOT_RECRUITING
Conditions: Autoimmune Hepatitis
Interventions: BIOLOGICAL: VAY736|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The ROAMM-EHR Study
Status: RECRUITING
Conditions: Peripheral Arterial Disease|Chronic Limb-Threatening Ischemia
Interventions: BEHAVIORAL: Actionable remotely generated health data|BEHAVIORAL: Non-Actionable remotely generated health data
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combining CES Alpha-Stim and InterX for Optimized Rehabilitation Following Extremity Immobilization
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DEVICE: NIN|DEVICE: Sham CES|DEVICE: CES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Hyperpolarized (HP) 13C Pyruvate Magnetic Resonance Imaging (MRI) for Response Monitoring to Neoadjuvant Abiraterone
Status: NOT_YET_RECRUITING
Conditions: High Risk Prostate Carcinoma|Prostate Cancer
Interventions: DRUG: Abiraterone acetate|DRUG: Prednisone|DRUG: Hyperpolarized [1-13C] pyruvate (HP 13C)|PROCEDURE: Magnetic Resonance Imaging (MRI)|PROCEDURE: Non-investigational radical prostatectomy (RP)|PROCEDURE: Prostate-Specific Membrane Antigen (PSMA) Positron Emission Tomography (PET) PET/Computerized tomography (CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Data Visualization of Kidney and Prostate Tumors Using Routine Pre-Operative Imaging, 3D Printed, and 3D Virtual Reality Models
Status: COMPLETED
Conditions: Pleural Effusion
Interventions: DIAGNOSTIC_TEST: Routine CT|DIAGNOSTIC_TEST: Routine imaging CT with a 3D printed model|DIAGNOSTIC_TEST: Routine imaging MRI with a 3D printed model|DIAGNOSTIC_TEST: Routine MRI|DIAGNOSTIC_TEST: Routine imaging CT with a VR model|DIAGNOSTIC_TEST: Routine imaging MRI with a VR model
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Therapeutic Efficacy of Quercetin Versus Its Encapsulated Nanoparticle on Tongue Squamous Cell Carcinoma Cell Line
Status: UNKNOWN
Conditions: Oral Cancer
Interventions: DRUG: Quercetin 3,3',4',5,6-Pentahydroxyflavone, 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one|DRUG: Quercetin-encapsulated PLGA-PEG nanoparticles (Nano-QUT)|DRUG: Doxorubicin chemotherapeutic drug as a positive control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Wound Drains for the Prevention Of Surgical sITe infectION
Status: COMPLETED
Conditions: Surgical Site Infection|Gynecologic Cancer|Wound Drain
Interventions: PROCEDURE: Surgical drain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lowering Food Insecurity and Improving Diabetes With Financial Incentives
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Monthly Unconditional Financial Incentive|BEHAVIORAL: Weekly Food Purchasing Financial Incentive|BEHAVIORAL: Glycemic Control Financial Incentive|BEHAVIORAL: Diabetes Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effects of Playing Live Music in Music Therapy/Occupational Therapy Co-treatment on Unilateral Spatial Neglect
Status: COMPLETED
Conditions: Unilateral Spatial Neglect (USN)
Interventions: BEHAVIORAL: Music Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of AT-02 in Healthy Volunteers and Subjects With Systemic Amyloidosis
Status: RECRUITING
Conditions: Amyloidosis; Systemic
Interventions: DRUG: AT-02|OTHER: AT-02 (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Surufatinib in Combination With Gemcitabine in Pediatric, Adolescent, and Young Adult Patients With Recurrent or Refractory Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor|Lymphoma|Osteosarcoma|Ewing Sarcoma|Rhabdomyosarcoma|Non-rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)
Interventions: DRUG: Surufatinib in combination with Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stabilometry Changes After Dry Needling in Flexor Digitoum Brevis
Status: COMPLETED
Conditions: Healthy|Foot|Dry Needling
Interventions: OTHER: Bilateral dry needling in latent trigger points of the Flexor digitorum Brevis Muscle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Arrhythmia Radioablation for Ventricular Tachycardia (StAR-VT)
Status: ENROLLING_BY_INVITATION
Conditions: Ventricular Tachycardia|Arrhythmia|Arrhythmic Storm|Radiation Toxicity
Interventions: RADIATION: stereotactic body radiotherapy, 20 Gy in 1 fraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kinesio Taping in Sit to Stand Movement fo Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Kinesio taping|OTHER: Without taping
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ropivacaine During Popliteal Nerve Block in Foot and Ankle Surgery
Status: UNKNOWN
Conditions: Popliteal Nerve Block|Foot Surgery|Ankle Surgery
Interventions: DRUG: Ropivacaine 0.5% Injectable Solution|DRUG: Ropivacaine 0.25% Injectable Solution|DRUG: Percocet Pill|DRUG: Norco Pill|PROCEDURE: Foot/Ankle Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Compound Betamethasone Injection Combined With Ropivacaine in Ultrasound-guided Intercostal Nerve Block for Chronic Post-thoracotomy Pain
Status: UNKNOWN
Conditions: Nerve Block
Interventions: OTHER: intercostal nerve block|OTHER: lateral intercostal nerve block|DRUG: ropivacaine + compound betamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Efficacy and Safety of BIVV009 (Sutimlimab) in Participants With Primary Cold Agglutinin Disease Without A Recent History of Blood Transfusion
Status: COMPLETED
Conditions: Cold Agglutinin Disease
Interventions: DRUG: sutimlimab (BIVV009)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Proton-chemotherapy for Locally Advanced Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: RADIATION: Proton, Gemcitabine, Erlotinib, Capecitabine|RADIATION: Proton Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Wound Infiltration With Extended-release Bupivacaine Before Laparoscopic or Robotic Hysterectomy
Status: COMPLETED
Conditions: Pain, Postoperative|Surgical Procedure, Unspecified
Interventions: DRUG: Liposomal Bupivacaine|DRUG: Bupivacaine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Determine Safety & Efficacy Of Autologous Human Platelet Lysate in Androgenetic Alopecia After Hair Transplant
Status: UNKNOWN
Conditions: Androgenetic Alopecia
Interventions: BIOLOGICAL: Autologous Human Platelet Lysate|BIOLOGICAL: Autologous Human Platelet Lysate|OTHER: Standard hair follicle transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of the Ulcerative Colitis Diet for Induction of Remission
Status: TERMINATED
Conditions: Ulcerative Colitis (UC)
Interventions: OTHER: Ulcerative Colitis Diet|DRUG: Antibiotic cocktail
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptance of a Partially Hydrolyzed Formula
Status: COMPLETED
Conditions: Fussy Infant (Baby)
Interventions: OTHER: Infant Formula - Partially hydrolyzed protein|OTHER: Infant Formula - Intact protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigating Predictors of Treatment Response in Treatment-Resistant Depression (TRD) With Interleaved TMS/fMRI
Status: COMPLETED
Conditions: Major Depressive Disorder|Depression
Interventions: DEVICE: repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pressure Enabled Delivery of SD-101 With Checkpoint Blockade for Primary Liver Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma|Intrahepatic Cholangiocarcinoma
Interventions: DRUG: SD-101|BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive of Proximal Humerus Fractures With Internal Fixation Improves Shoulder Function in Older Patients
Status: COMPLETED
Conditions: Humerus Fractures
Interventions: DEVICE: locking compression plate group|DEVICE: conventional locking plate group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FR901228 in Treating Patients With Myelodysplastic Syndrome, Acute Myeloid Leukemia, or Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: DRUG: romidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Clinical Re-evaluation of Removing Blood Stasis Therapy in Treating Acute Cerebral Hemorrhage Safety and Efficacy
Status: UNKNOWN
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: ICH-1(herbal medicine with Hirudo, Tabanus)|DRUG: placebo|DRUG: ICH-2(herbal medicine without Hirudo, Tabanus)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of PFC tDCS on Cognitive Control, Attention Lapses and Coordinated Neural Activity in the Theta and Alpha Bands
Status: RECRUITING
Conditions: Healthy
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sustainable Intervention of Supplementation to Improve Kid's Growth Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Birth Length|Linear Growth|Micronutrients|Dietary Intakes
Interventions: DIETARY_SUPPLEMENT: Micronutrient Enriched Crackers (MECs)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of DEB-BACE Combined With PD-1 Inhibitors in Stage II/III NSCLC With Standard Treatment Failure
Status: NOT_YET_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: PROCEDURE: Drug-eluting beads bronchial arterial chemoembolization|DRUG: Programmed Cell Death Protein 1 Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Polydiuretic Therapy for HFpEF, a Randomised Controlled Trial
Status: RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: Low dose combination polydiuretic therapy|DRUG: Comparator monotherapy empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Understanding Circadian Responses to Light in Persons With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Alzheimer Disease
Interventions: DEVICE: Lighting Intervention Blue light|DEVICE: Lighting Intervention Green light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Predictors of Normal Tissue Response From the Microenvironment in Radiotherapy for Prostate and Head-and-neck Cancer
Status: UNKNOWN
Conditions: Prostate Cancer|Head and Neck Cancer
Interventions: RADIATION: External beam radiotherapy for prostate cancer|RADIATION: External beam radiotherapy for head and neck cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: AV2 Antiviral Spray Versus Placebo in Human Papillomavirus Cervix Infections
Status: UNKNOWN
Conditions: Genital Human Papilloma Virus Infection
Interventions: DRUG: topical application cervical spray|DRUG: topical spray on the cervix|PROCEDURE: cervical swab with Cervex-Brush-Combi at T0|PROCEDURE: cervical swab with Cervex-Brush-Combi at T1|PROCEDURE: cervical swab with Cervex-Brush-Combi at T0|PROCEDURE: cervical swab with Cervex-Brush-Combi at T1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Database Study to Estimate the Risk of Multiple Sclerosis Following Vaccination With Arepanrix™ in Manitoba, Canada
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: Exposed to Arepanrix™ Cohort|OTHER: Unexposed to Arepanrix™ Cohort
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pioglitazone vs Vitamin E vs Placebo for Treatment of Non-Diabetic Patients With Nonalcoholic Steatohepatitis (PIVENS)
Status: COMPLETED
Conditions: Liver Diseases
Interventions: DRUG: Pioglitazone|DIETARY_SUPPLEMENT: Vitamin E|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thalidomide/Dexamethasone Treatment And PET Evaluation In Organ Involvemenet of Cardiac Amyloidosis
Status: UNKNOWN
Conditions: Cardiac Amyloidosis
Interventions: DRUG: Thalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Weight-based Versus External Ear-size Based Technique for Selection of Laryngeal Mask Airway in Pediatric Surgical Patients.
Status: COMPLETED
Conditions: Laryngeal Masks|Minors|Child|Pediatrics
Interventions: DEVICE: Ear Size Based Method (Ambu® AuraOnce™ Laryngeal Mask Airway)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Light-Emitting Diode (LED) Light for Seasonal Affective Disorder (SAD) Treatment
Status: UNKNOWN
Conditions: Seasonal Affective Disorder
Interventions: DEVICE: light exposure from LED source at narrow 468 nm or broader 400-700 nm wavelength
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dynamic Flex Cast With Neurodevelopmental Treatment on Gross Motor Functions in Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Dynamic flex cast with neurodevelopmental treatment|OTHER: Rigid Ankle foot Orthosis with neurodevelopmental treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicentre Study To Assess Changes In Bone Mineral Density Of The Switch From Protease Inhibitors To Dolutegravir In HIV-1-Infected Subjects With Low Bone Mineral Density
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Dolutegravir, 50mg every 24 hours|DRUG: Protease Inhibitor/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ABT-384 in Elderly Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ABT-384|DRUG: Matching placebo to ABT-384
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Axitinib in Patients With Metastatic Renal Cell Cancer Unsuitable for Nephrectomy
Status: COMPLETED
Conditions: Clear-cell Metastatic Renal Cell Carcinoma
Interventions: DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Augmenting Single-session Behavioral Activation (BA) With Delta-beta Transcranial Alternating Current Stimulation (tACS) for the Treatment of Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: Delta-beta cross-frequency transcranial alternating current stimulation via the NeuroConn DC-STIMULATOR MC|BEHAVIORAL: Single-session behavioral activation|DEVICE: Active sham cross-frequency transcranial alternating current stimulation via the NeuroConn DC-STIMULATOR MC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Financially Sustainable Remote Treatment for Alcohol Abuse: Feasibility
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: BEHAVIORAL: Contingency management: Contingent incentives|BEHAVIORAL: Contingency management: Noncontingent incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Maternal Vitamin A or Beta-Carotene Supplementation on Maternal and Infant Mortality in Bangladesh
Status: COMPLETED
Conditions: Vitamin A Deficiency|Maternal Mortality|Infant Mortality
Interventions: DIETARY_SUPPLEMENT: Vitamin A or Beta-Carotene Supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Behavioral Therapy for Anxiety and Depression in COPD
Status: COMPLETED
Conditions: Anxiety|Depression|Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Cognitive behavioral therapy|BEHAVIORAL: Minimal Telephone Contact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of NV-101 for Safety and Efficacy in Pediatric Dental Patients Undergoing Procedures
Status: COMPLETED
Conditions: Anesthesia, Dental
Interventions: DRUG: Phentolamine Mesylate (NV-101)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of R-CHOP vs R-CHOP/R-DHAP in Untreated MCL
Status: UNKNOWN
Conditions: Lymphoma, Mantle-Cell
Interventions: DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|DRUG: Cisplatinum|DRUG: Ara-C|DRUG: Dexamethasone|DRUG: BCNU|DRUG: Melphalan|DRUG: Etoposide|DRUG: G-CSF|PROCEDURE: chemotherapy: R-CHOP|PROCEDURE: chemotherapy: R-DHAP|PROCEDURE: chemotherapy: Dexa-BEAM|PROCEDURE: stem cell harvest|PROCEDURE: total body irradiation|PROCEDURE: high-dose chemotherapy: Cyclophosphamide|PROCEDURE: high-dose chemotherapy: Ara-C /Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin K2 Over Osteocalcin, Leptin, Cytokines, and Cardiovascular Risk in Young Adults With Overweight and Obesity
Status: COMPLETED
Conditions: Overweight and Obesity|Cardiometabolic Risk Factors
Interventions: DIETARY_SUPPLEMENT: Vitamin K2|OTHER: Cornstarch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Telemedicine Versus Traditional Practice in a University Health Center
Status: TERMINATED
Conditions: Health Service Research on Telemedicine
Interventions: OTHER: Traditional versus Telemedicine office visit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Relationship Between Myocardial Blush Grade and T-P-e Interval and QRS Width: Impact on In-Hospital Outcome After Successful Primary Percutaneous Coronary Intervention
Status: NOT_YET_RECRUITING
Conditions: Myocardial Infarction
Interventions: PROCEDURE: primary percutaneous intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Tele-spirometry in Primary Care - Randomized Clinical Trial Cluster: the Effectiveness of Telemedicine in Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: OTHER: telemonitoring|OTHER: Spirometry (baseline)|OTHER: Spirometry (20 - 22weeks)|OTHER: Teleconsultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Allopregnanolone for Mild Cognitive Impairment Due to Alzheimer's Disease or Mild AD
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Alzheimer Disease
Interventions: DRUG: Allopregnanolone injection (intravenous solution)|DRUG: Placebo injection (intravenous solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of a Robot-assisted Intervention for the Management of Care-induced Pain in Dementia
Status: COMPLETED
Conditions: Moderate to Severe Dementia
Interventions: BEHAVIORAL: A : Systemic evaluation of the pain and mediation with the PARO therapeutic robot|BEHAVIORAL: B : Systemic evaluation of the pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Monoclonal Antibody CT-011 in Combination With Rituximab in Patients With Relapsed Follicular Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: CT-011|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Omega-3 Trial to Prevent and Treat Diabetic Kidney Disease
Status: COMPLETED
Conditions: Diabetes
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DRUG: Omega-3 fatty acids (fish oil)|DIETARY_SUPPLEMENT: Vitamin D placebo|DIETARY_SUPPLEMENT: Fish oil placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Descemet Membrane Endothelial Keratoplasty Combined With Intraocular Lens Exchange: Sequential Versus Combined Surgery
Status: UNKNOWN
Conditions: Pseudophakic Bullous Keratopathy|Anterior Chamber Intraocular Lens
Interventions: PROCEDURE: Descemet membrane endothelial keratoplasty DMEK|PROCEDURE: IOL exchange|PROCEDURE: iridoplasty|PROCEDURE: Inferior peripheral iridectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Couple-Based Treatment for Alcohol Use Disorders and Post-Traumatic Stress Disorder
Status: COMPLETED
Conditions: Alcohol-related Disorders|Post-traumatic Stress Disorder
Interventions: BEHAVIORAL: Couple-Based Treatment for Alcohol Use Disorders and PTSD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Interplay Between Deciding and Acting With Mild Cognitive Impairment
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Reaching Movements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Closing the Loop in Adults With Sub-optimally Controlled Type 1 Diabetes Under Free Living Conditions
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Florence D2A or similar closed loop glucose control system|DEVICE: CSII with real-time CGM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azithromycin in Patients With CF, Infected With Burkholderia Cepacia Complex
Status: UNKNOWN
Conditions: Cystic Fibrosis
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of New Magnetic Resonance Imaging (MRI) Pulse Sequences for Imaging Hyperpolarised Xenon in Lung, Heart and Brain in Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: Hyperpolarised Xenon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate a Modified RNA Vaccine Against Influenza in Adults 18 Years of Age or Older
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: Quadrivalent influenza modRNA vaccine|BIOLOGICAL: Quadrivalent influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Normative Database of Healthy Subject Vascular Density Using Spectralis Heidelberg® Optical Coherence Tomography Angiography
Status: RECRUITING
Conditions: Optical Coherence Tomography|Optical Coherence Tomography Angiography
Interventions: OTHER: Optical coherence tomography angiography|OTHER: ophthalmological exam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cardiac Stem/Progenitor Cell Infusion in Univentricular Physiology (APOLLON Trial)
Status: UNKNOWN
Conditions: Hypoplastic Left Heart Syndrome|Single Ventricle
Interventions: GENETIC: Autologous cardiac stem cells (JRM-001)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of [177Lu]Lu-FF58 in Patients With Advanced Solid Tumors.
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma|Gastroesophageal Adenocarcinoma|Glioblastoma Multiforme
Interventions: DRUG: 68Ga-FF58|DRUG: 177Lu-FF58
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Piperacillin-tazobactam and Temocillin as Carbapenem-alternatives for the Treatment of Severe Infections Due to Extended-spectrum Beta-lactamase-Producing Gram-negative Enterobacteriaceae in the Intensive Care Unit
Status: RECRUITING
Conditions: Sepsis|Septic Shock
Interventions: DRUG: Piperacillin/tazobactam or temocillin|DRUG: Meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Sonographically Versus Fluorescence-guided Resection of Contrast-enhancing Gliomas and Brain Metastases
Status: RECRUITING
Conditions: Gliomas, Malignant|Metastases to Brain
Interventions: DEVICE: Ultrasound guided brain tumor resection|DEVICE: 5-aminolevulinic acid fluorescence-guided brain tumor resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT