pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: IN10018 in Combination With Pegylated Liposomal Doxorubicin (PLD) vs. Placebo in Combination With PLD for the Treatment of Platinum-resistant Recurrent Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer Recurrent
Interventions: DRUG: IN10018|DRUG: Placebo of IN10018|DRUG: Pegylated Liposomal Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Single Versus Double Incision to Repair Distal Bicep Tendon Ruptures
Status: COMPLETED
Conditions: Distal Bicep Tendon Rupture
Interventions: PROCEDURE: Distal bicep tendon reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Barotrauma in Hyperbaric Oxygen Therapy
Status: RECRUITING
Conditions: Barotrauma
Interventions: DRUG: Pseudoephedrine Pill|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Performance Comparison of Several Different Contact Lenses
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: senofilcon A|DEVICE: lotrafilcon B|DEVICE: balafilcon A|DEVICE: methafilcon A|DEVICE: vifilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Health Determinants in Older Adults Living at Home
Status: RECRUITING
Conditions: Frailty|Vision and Hearing Loss|Cognitive Function, Social 1|Mental Health Issue|Social Functioning|Alcohol Use, Unspecified|Healthy Aging
Interventions: BEHAVIORAL: Health promoting assessment of older adults living at home
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigate the Safety/Tolerability and Efficacy of Bilastine 20mg in Korean Patients With Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Bilastine|DRUG: Desloratadine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: QUILT-3.013: Study of Ad5 [E1-, E2b-]-HER2/Neu Vaccine (ETBX-021) in Subjects With Unresectable Locally Advanced or Metastatic HER2-Expressing Breast Cancer
Status: UNKNOWN
Conditions: Cancer
Interventions: BIOLOGICAL: ETBX-021
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Topical Sinonasal Budesonide Irrigation on Hypothalamic-Pituitary-Adrenal Axis Function
Status: TERMINATED
Conditions: Chronic Rhinosinusitis
Interventions: DRUG: Budesonide irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between Serum Levels of Angiogenin, bFGF, VEGF and Ocular Involvement in Patients With Behçet's Disease
Status: COMPLETED
Conditions: Behçet's Disease
Interventions: OTHER: serum levels of angiogenin, bFGF, VEGF
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vitamin D for Sickle-cell Respiratory Complications
Status: COMPLETED
Conditions: Sickle Cell Disease|Vitamin D Deficiency|Acute Chest Syndrome|Asthma|Respiratory Infections
Interventions: DRUG: Experimental: Vitamin D3 100,000 IU|DRUG: Active Comparator: Vitamin D3 12,000 IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Mesenchymal Stem Cell Transplantation in Tibial Closed Diaphyseal Fractures
Status: COMPLETED
Conditions: Tibial Fracture
Interventions: BIOLOGICAL: Mesenchymal stem cell injection|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Partnership for Research on Ebola VACcinations
Status: COMPLETED
Conditions: Ebola Virus Disease
Interventions: BIOLOGICAL: Ad26.ZEBOV|BIOLOGICAL: MVA-BN-Filo|BIOLOGICAL: rVSVΔG-ZEBOV-GP|BIOLOGICAL: Placebo|BIOLOGICAL: rVSV boost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Universal 4SCAR7U Targeting CD7-positive Malignancies
Status: RECRUITING
Conditions: T-cell Acute Lymphoblastic Leukemia|T-cell Acute Lymphoblastic Lymphoma|Acute Myeloid Leukemia|NK Cell Lymphoma
Interventions: BIOLOGICAL: Universal CD7-specific CAR gene-engineered T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plastic Hat Trial to Prevent Hypothermia in Preterm Newborns in the Delivery Room
Status: COMPLETED
Conditions: Hypothermia
Interventions: OTHER: placement of plastic cap during delivery room stabilization|OTHER: placement of routine cap during delivery room stabilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Monthly Replacement Orthokeratology for Myopia Control in Young Children
Status: UNKNOWN
Conditions: Myopic Progression
Interventions: DEVICE: orthokeratology|DEVICE: Menicon Progent A+B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cyclo-Ergometry in the Patient With Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Coronavirus
Interventions: OTHER: Bed cyclo-ergonometry|OTHER: Bed mobility activities (turning, pelvic elevation and sitting), standing, transfers and walking.|OTHER: Progressive upper and lower limb strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ADAM17 and Vascular Function in Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Phosphatidylserine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Linking Altered Central Pain Processing and Genetic Polymorphism to Drug Efficacy in Chronic Low Back Pain (Predictio)
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Oxycodone 15mg|DRUG: Clobazam|DRUG: Imipramine|DRUG: Tolterodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study of the Combination of Anlotinib and Aumolertinib in the First-line Treatment of Advanced NSCLC With EGFR 21L858R Mutation
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor
Interventions: DRUG: Combined therapy of anlotinib and aumolertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Chlamydia Vaccine CTH522
Status: COMPLETED
Conditions: Trachoma
Interventions: BIOLOGICAL: CTH522-CAF01 IM|BIOLOGICAL: CTH522-CAF09b IM|BIOLOGICAL: CTH522 ID|BIOLOGICAL: CTH522 TO|BIOLOGICAL: Placebo (Saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reducing Self-Stigma Among Individuals With History of Childhood Maltreatment
Status: RECRUITING
Conditions: Stigma, Social|Child Abuse|Child Neglect|Help-Seeking Behavior
Interventions: BEHAVIORAL: Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Phase II Study of Regorafenib Continuous Dosing of Regorafenib in Patients With GISTs
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors (GISTs)
Interventions: DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Apnea in Late Preterm and Term Infants
Status: WITHDRAWN
Conditions: Apnea
Interventions: DRUG: Caffeine citrate|DEVICE: Home monitor|OTHER: Continued inpatient monitoring until apnea resolution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Luteal Phase Ovarian Stimulation With Follitropin Delta and Dydrogesterone
Status: RECRUITING
Conditions: Oocyte Donors|Oocyte Donation
Interventions: DRUG: Follitropin delta (Rekovelle)|DRUG: Duphaston|DRUG: GnRH agonist (Gonapeptyl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of L-cysteine in Prevention of Cluster Headache
Status: COMPLETED
Conditions: Cluster Headache
Interventions: DRUG: Acetium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanism of Action of Transcranial Direct Current Stimulation in Neurofibromatosis Type 1
Status: COMPLETED
Conditions: Neurofibromatosis 1
Interventions: OTHER: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase IV Study, of the Efficacy, Safety, and Acceptability of Moviprep® Versus Colopeg® in Colonoscopy Preparation
Status: COMPLETED
Conditions: Gastrointestinal Diseases
Interventions: DRUG: MOVIPREP|DRUG: COLOPEG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thrice-weekly Versus Thrice-daily Oral Ferrous Fumarate Treatment in Adult Patients With Iron Deficiency Anemia
Status: COMPLETED
Conditions: Iron Deficiency Anemia
Interventions: DRUG: Ferrous Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebral Autoregulation Guiding Blood Pressure Management After Revascularization
Status: NOT_YET_RECRUITING
Conditions: Ischemic Stroke|Revascularization|Blood Pressure|Cerebrovascular Insufficiency|Cerebral Autoregulation|Individuation|Hemorrhagic Transformation Due to Acute Stroke
Interventions: DRUG: Hypotensive Drugs and/or Vasoactive Drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid-induced Bowel Dysfunction Pivotal Assessment of Lubiprostone
Status: COMPLETED
Conditions: Opioid-Induced Bowel Dysfunction
Interventions: DRUG: Lubiprostone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transdermal Neuromodulation for Management of Chronic Pelvic Pain in Women
Status: COMPLETED
Conditions: Pelvic Pain Syndrome
Interventions: DEVICE: Percutaneous Posterior Tibial Nerve Stimulation|DEVICE: Placebo Percutaneous Posterior Tibial Nerve Stimulation|BEHAVIORAL: Home instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Disease Activity in Adult Participants With Axial Spondyloarthritis Who Receive Upadacitinib in a Real-world Setting
Status: RECRUITING
Conditions: Axial Spondylarthritis (r-axSpA)
Interventions: DRUG: Upadacitinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase Ib/III Clinical Study to Evaluate the Efficacy and Safety of IBI318 in Combination With Paclitaxel Versus Placebo in Combination With Paclitaxel in Patients With Small Cell Lung Cancer Who Have Failed First-line or Above Chemotherapies
Status: COMPLETED
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: paclitaxel|DRUG: IBI318
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Extension Study for Patients Who Have Previously Participated and Have Benefited From Iniparib in a Clinical Trial
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Iniparib (SAR240550/BSI-201)|DRUG: Carboplatin|DRUG: Doxorubicin HCL liposome injection|DRUG: Gemcitabine|DRUG: Irinotecan|DRUG: Paclitaxel|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Investigate the Long-term Safety of the Drug Macitentan in Patients With Pulmonary Hypertension Who Were Previously Treated With Macitentan in Clinical Studies.
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension|Chronic Thromboembolic Pulmonary Hypertension
Interventions: DRUG: macitentan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthy Relationships Training Study: A Comparison of Interventions to Reduce Dating Violence on College Campuses
Status: COMPLETED
Conditions: Dating Violence
Interventions: BEHAVIORAL: Mindfulness-Based Skills Training (MBST)|BEHAVIORAL: Psychoeducational
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An fMRI Study of Treatment Optimization Comparing Two Disease Modifying Therapies Used to Treat Relapsing Remitting Multiple Sclerosis
Status: TERMINATED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: Glatiramer acetate, (Copaxone®)|DRUG: IFN-β-1a, (Avonex®)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Outcomes of Non-surgical Versus Surgical Treatment of Shoulder Fractures With Different Shoulder Replacements
Status: ACTIVE_NOT_RECRUITING
Conditions: Proximal Humeral Fracture|Humeral Head Fracture
Interventions: PROCEDURE: Non-operative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Melatonin in the Prophylaxis of Coronavirus Disease 2019 (COVID-19) Among Healthcare Workers.
Status: COMPLETED
Conditions: Covid19|SARS-CoV 2|Coronavirus Infection
Interventions: DRUG: Melatonin 2mg|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors
Status: RECRUITING
Conditions: Metastatic Melanoma|Squamous Cell Carcinoma of the Head and Neck|Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Lifileucel|BIOLOGICAL: LN-145|DRUG: Pembrolizumab|BIOLOGICAL: LN-145-S1|DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene Therapy for the Treatment of Brain Tumors
Status: COMPLETED
Conditions: Brain Neoplasm|Neoplasm Metastasis
Interventions: DRUG: Cytovene (Ganciclovir Sodium)|DEVICE: G1TKSVNa.53 Producer Cell Line
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Exendin (9-39) on Glucose Requirements to Maintain Euglycemia
Status: TERMINATED
Conditions: Congenital Hyperinsulinism
Interventions: DRUG: Exendin (9-39)|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Fibrosis During Severe COVID-19 Pneumonia
Status: ACTIVE_NOT_RECRUITING
Conditions: Severe Acute Respiratory Syndrome Coronavirus 2|Acute Respiratory Distress Syndrome|Pulmonary Fibrosis
Interventions: DIAGNOSTIC_TEST: Aminoterminal type III peptide of procollagen|DIAGNOSTIC_TEST: Lung computed tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Platform Study to Evaluate the Efficacy and Safety of Anti-malarial Agents in Patients With Uncomplicated Plasmodium Falciparum Malaria
Status: RECRUITING
Conditions: Uncomplicated Plasmodium Falciparum Malaria
Interventions: DRUG: INE963|DRUG: KAE609 (Cipargamin)|DRUG: SoC (Coartem)|DRUG: KLU156
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of IGNX001
Status: NOT_YET_RECRUITING
Conditions: Peanut Allergy
Interventions: DRUG: IGNX001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MOPEXE and RE in Treating Dysmenorrhea
Status: COMPLETED
Conditions: Dysmenorrhea|Gynecologic Disease
Interventions: OTHER: MOPEX Exercise|OTHER: Relaxation Exercise|OTHER: Combine Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dalteparin vs Unfractionated Heparin For The Prevention Of Venous Thromboembolism (VTE) In Hospitalized Acutely Ill Medical Patients
Status: TERMINATED
Conditions: Venous Thromboembolism
Interventions: DRUG: Dalteparin (Fragmin)|DRUG: Unfractionated heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Intranasal vs Intravenous Dexmedetomidine for EEG Sedation of Children With Behavior Disorders.
Status: COMPLETED
Conditions: Sedation Complication
Interventions: DRUG: dexmedetomidine (IV)|DRUG: dexmedetomidine (IN)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Resection And Partial LIver Transplantation With Delayed Hepatectomy for Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: RAPID procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Technology/Digital Media Use and Children's Word Learning Development
Status: WITHDRAWN
Conditions: Healthy
Interventions: BEHAVIORAL: Modality - 3D-2D|BEHAVIORAL: Modality - 2D-3D|BEHAVIORAL: Modality - 2D-2D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Tolerability Study of Suprachoroidal Injection of CLS-AX Following Anti-VEGF Therapy in Neovascular AMD
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: CLS-AX|DRUG: Anti-VEGF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diclofenac vs. Ropivacaine for Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section
Interventions: DRUG: Ropivacaine, Diclofenac, Water for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Understanding Food Choices in Saudi Arabia- Taxes
Status: COMPLETED
Conditions: Diet, Healthy
Interventions: BEHAVIORAL: Implicit Tax|BEHAVIORAL: Explicit Tiered Tax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: XIENCE V® Everolimus Eluting Coronary Stent System India Post-marketing Single-arm Study
Status: COMPLETED
Conditions: Coronary Disease|Coronary Artery Disease|Coronary Restenosis
Interventions: DEVICE: XIENCE V® Everolimus Eluting Coronary Stent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Open-label Study to Evaluate the Absorption, Metabolism, and Excretion of [14C]-Telotristat Etiprate in Males
Status: COMPLETED
Conditions: Carcinoid Syndrome
Interventions: DRUG: 500 mg [14C]-LX1606
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Video Based Directly Observed Therapy for Latent TB
Status: WITHDRAWN
Conditions: Latent Tuberculosis
Interventions: DRUG: Rifapentine 600 mg orally|DRUG: Isoniazid 900 mg orally|DRUG: Pyridoxine 50 mg orally
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effectiveness of Rt-CGM to Improve Glycemic Control and Pregnancy Outcome in Patients With GDM
Status: RECRUITING
Conditions: Cgm|Gestational Diabetes|Pregnancy Complications|Blood Glucose|GDM
Interventions: DEVICE: Dexcom G6 Continuous Glucose Monitoring System|DEVICE: self-monitored blood glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Micro Ribonucleic Acid (miRNA) Markers of Hydrocephalus in Intraventricular Hemorrhage (IVH)
Status: TERMINATED
Conditions: Intraventricular Hemorrhage|Spina Bifida
Interventions: GENETIC: collection of CSF and blood
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: AQ4N in Combination With Radiotherapy and Temozolomide in Subjects With Newly Diagnosed Glioblastoma Multiforme
Status: UNKNOWN
Conditions: Glioblastoma Multiforme
Interventions: DRUG: AQ4N|DRUG: Temozolomide|PROCEDURE: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Transcranial Direct Current Stimulation (tDCS) on Motor and Cognitive Functions in Idiopathic Fallers
Status: UNKNOWN
Conditions: Elderly Idiopathic Fallers
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Helicobacter Pylori Eradication Therapy in Portugal
Status: RECRUITING
Conditions: Helicobacter Pylori|Gut Microbiota|Immunology
Interventions: DRUG: H. pylori eradication scheme A|DRUG: H. pylori eradication scheme B|DRUG: H. pylori eradication scheme C|DRUG: H. pylori eradication scheme D|DRUG: H. pylori eradication scheme E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Fascial Release Technique in Patients With Rotator Cuff Repair
Status: COMPLETED
Conditions: Arthroscopic Rotator Cuff Repair
Interventions: OTHER: conventional physiotherapy|OTHER: fascial release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sodium-glucose Cotransporter-2 Inhibitor in Cellular Senescence in Patients With Cardiovascular Diseases or Type 2 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus|Cellular Senescence|Sodium-Glucose Transporter 2 Inhibitors
Interventions: DRUG: SGLT2 inhibitor|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NKI Therapy Compared to Usual Care of Recurrent Esophagogastric Anastomotic Strictures
Status: TERMINATED
Conditions: Esophageal Stricture|Anastomotic Stenosis|Dilation of Esophagus Due to Disease
Interventions: PROCEDURE: NKI followed by EBD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subretinal Transplantation of Retinal Pigment Epitheliums in Treatment of Age-related Macular Degeneration Diseases
Status: UNKNOWN
Conditions: Dry Age-related Macular Degeneration
Interventions: BIOLOGICAL: retinal pigment epithelium transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Washed Microbiota Transplantation Alleviates Diabetic Gastrointestinal Motility Disorders: an Efficacy and Safety Study
Status: NOT_YET_RECRUITING
Conditions: Diabetic Gastroparesis|Diabetic Gastropathy|Diabetic Gastroenteropathy|Diabetic Gastroparesis Associated With Type 2 Diabetes Mellitus
Interventions: OTHER: Washing Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Project OASIS: Optimizing Approaches to Select Implementation Strategies
Status: ENROLLING_BY_INVITATION
Conditions: Cirrhosis|Hepatocellular Carcinoma
Interventions: BEHAVIORAL: OASIS DA training|BEHAVIORAL: Current DA Tool training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: [68Ga]Ga-PentixaFor-PET Imaging for Staging of Marginal Zone Lymphoma
Status: RECRUITING
Conditions: Marginal Zone Lymphoma
Interventions: DRUG: [68Ga]Ga-PentixaFor|DRUG: [18F]Fluorodeoxyglucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Potential of Carnosine Supplementation in Optimising Cardiometabolic Health
Status: UNKNOWN
Conditions: Poor Glycemic Control|Cardiovascular Risk Factors|Cognitive Function 1, Social
Interventions: DIETARY_SUPPLEMENT: carnosine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vascular Access in Hematological Patients - PICC Versus CVC
Status: COMPLETED
Conditions: Vascular Access Complication
Interventions: DEVICE: Centrally inserted central catheters (CICCs)|DEVICE: Peripherally inserted central catheters (PICCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Harmonic Scalpel and Ligasure Devices in Laparoscopic Morbid Obesity Surgery
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: DEVICE: Harmonic scapel|DEVICE: Ligasure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study of the Effect of Pneumococcal Conjugate Vaccine (PCV) on Immunogenicity of Pentacel™
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Haemophilus Infection|Pertussis|Polio
Interventions: BIOLOGICAL: Pentacel™: HCPDT-IPV//PRP-T Vaccine and Prevnar®|BIOLOGICAL: Pentacel™: HCPDT-IPV//PRP-T Vaccine and Prevnar®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparing the Efficacy of Nab-PH+Pyrrolitinib and TCbHP in the Neoadjuvant Treatment of HER2 Positive BC
Status: RECRUITING
Conditions: Breast Cancer|HER2-positive Breast Cancer
Interventions: DRUG: Albumin paclitaxel+trastuzumab+pyrrolitinib|DRUG: Docetaxel+Carboplatin+trastuzumab+Parstuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug-Drug Interaction (DDI) Study of Orforglipron With Carbamazepine in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Orforglipron|DRUG: Carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Staccato Prochlorperazine in Migraine (in Clinic)
Status: COMPLETED
Conditions: Migraine Headache, With or Without Aura
Interventions: DRUG: Staccato Placebo|DRUG: Staccato Prochlorperazine 5 mg|DRUG: Staccato Prochlorperazine 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Patching Versus Atropine for Amblyopia in 7 to < 13 Year Olds
Status: COMPLETED
Conditions: Amblyopia
Interventions: DRUG: Atropine|DEVICE: Patching|PROCEDURE: Near activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Near INfrared Spectroscopy in Aortic valvE ReplacemenT
Status: COMPLETED
Conditions: Aortic Valve Stenosis|Transcatheter Aortic Valve Implantation|Eligibility for Both Anaesthetic Methods
Interventions: PROCEDURE: General anaesthesia|PROCEDURE: Sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Abraxane as Maintenance Treatment After Abraxane Plus Carboplatin in 1st Line Stage IIIB / IV Squamous Cell Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Squamous Cell Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Abraxane (Induction)|DRUG: Carboplatin (Induction)|DRUG: Abraxane (Maintenance)|OTHER: Best Supportive Care (Maintenance)|DRUG: Abraxane (Induction)|DRUG: Carboplatin (Induction)|OTHER: Best Supportive Care (Maintenance)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pre-meal Serving of Dairy and Dairy Alternatives on Post-meal Satiety and Glycaemia in Healthy Young Adults
Status: COMPLETED
Conditions: Obesity|Type 2 Diabetes Mellitus
Interventions: OTHER: Dairy-based greek yogurt|OTHER: Dairy-based cheddar cheese|OTHER: Plant-based yogurt|OTHER: Plant-based cheese
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study of Bortezomib and Revlimid™ for Patients Relapsing or Progressing on Total Therapy II
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: CC-5013 (Revlimid™)|DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of an Emollient Containing Postbiotic Saccharomyces and Lactobacillus on Pediatric Atopic Dermatitis
Status: NOT_YET_RECRUITING
Conditions: Atopic Dermatitis|Eczema|Emollient
Interventions: OTHER: Treatment with an Emollient Containing Postbiotic Saccharomyces and Lactobacillus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention Study to Improve Maternal Handwashing
Status: WITHDRAWN
Conditions: Infection|Neonatal
Interventions: BEHAVIORAL: Clinic|BEHAVIORAL: Clinic + home|BEHAVIORAL: Clinic + home + handwashing device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: European Management Platform for Childhood Interstitial Lung Diseases - chILD-EU Register and Biobank
Status: RECRUITING
Conditions: Lung Diseases, Interstitial|Pulmonary Alveolar Proteinosis|Pulmonary Eosinophilia|Pulmonary Fibrosis|Respiratory Distress Syndrome, Newborn|Child
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Correlation Between Blood omega3 and ADHD
Status: UNKNOWN
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: PROCEDURE: blood test|DIETARY_SUPPLEMENT: omega3 capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The IM ABLE Study: A Study of Warriors & Veterans Following Neuromusculoskeletal Injury of the Lower Limb
Status: UNKNOWN
Conditions: Limb Salvage|Braces|Lower Extremity
Interventions: DEVICE: Advanced orthotic brace|DEVICE: Conventional orthotic brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LEO 80185 in the Treatment of Psoriasis Vulgaris on the Non-scalp Regions of the Body (Trunk and/or Limbs)
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Calcipotriol plus betamethasone|DRUG: Betamethasone-17,21-dipropionate|DRUG: Calcipotriene|DRUG: Topical suspension vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of EM and SM+ Maneuvers in Patients With BPPV
Status: COMPLETED
Conditions: BPPV
Interventions: PROCEDURE: Epley Maneuver|PROCEDURE: SemontPLUS maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib and Low Dose Cytarabine in Older Patients With Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Ascending Dose Study in Healthy Participants and Multiple Ascending Dose Study of CNTO 7160 in Participants With Asthma and Participants With Atopic Dermatitis
Status: COMPLETED
Conditions: Asthma|Atopic Dermatitis|Healthy
Interventions: DRUG: Part 1: CNTO 7160|DRUG: Part 2 (Asthma): CNTO 7160|DRUG: Part 2 (Atopic Dermatitis): CNTO 7160|DRUG: Part 1 and Part 2: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Effects of Raloxifene Treatment on Bone Quality
Status: COMPLETED
Conditions: Osteoporosis, Post-Menopausal
Interventions: DRUG: Raloxifene|DRUG: Raloxifene|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Auriculotherapy During Medication Abortion
Status: COMPLETED
Conditions: Abortion Early
Interventions: DEVICE: Auriculotherapy with needles|DEVICE: Auriculotherapy with beads|DEVICE: Placebo Adhesive disks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Virtual Intervention to Improve Medication Adherence in Pediatric Cancer: MedSupport
Status: COMPLETED
Conditions: Medication Adherence
Interventions: BEHAVIORAL: Patient participation|OTHER: Clinician barrier reports
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Mechanical Bone Stimulation and Adenosine 5'-Triphosphate (ATP) Release in Humans
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DEVICE: Juvent 1000 Vibration Platform
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose-reduced Versus Standard Conditioning in MDS/sAML
Status: TERMINATED
Conditions: Myelodysplastic Syndromes|Secondary Acute Myeloid Leukemia
Interventions: OTHER: Reduced Intensity Conditioning|OTHER: Myeloablative conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of No-option CLI by G-CSF-mobilized PB-MNC
Status: UNKNOWN
Conditions: PAD|Critical Limb Ischemia|Atherosclerotic Ischemic Disease
Interventions: PROCEDURE: PB-MNC therapy|DRUG: No-PB-MNC therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug Interaction Study of Valproic Acid and Single-dose Paliperidone Extended-Release (ER) in Healthy Men
Status: COMPLETED
Conditions: Schizophrenia|Epilepsy
Interventions: DRUG: paliperidone ER|DRUG: divalproex sodium ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Study of the Safety and Immune Response of a Meningococcal Vaccine Administered to Healthy Children
Status: COMPLETED
Conditions: Prevention of Meningococcal Disease
Interventions: BIOLOGICAL: MenACWY-CRM Vaccine|BIOLOGICAL: MenACWY-PS Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Evaluation on Performance and Oxydative Stress in Patient With Iron deficIency and Stable Heart Failure Study
Status: COMPLETED
Conditions: Chronic Heart Failure (CHF)|Iron Deficiency
Interventions: DRUG: Iron Sucrose IV|DRUG: Ferric polymaltose hydroxide complex IM|OTHER: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Pancreatic Enzyme Supplementation in Critically Ill Patients on Enteral Feeding
Status: RECRUITING
Conditions: Critically Ill|Enteral Feeding|Exocrine Pancreatic Insufficiency
Interventions: DRUG: Exocrine Pancreatic Enzyme|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: In Vivo Efficacy of Artemether-Lumefantrine and Artesunate-Amodiaquine for Uncomplicated P. Falciparum Malaria
Status: COMPLETED
Conditions: MALARIA, FALCIPARUM
Interventions: DRUG: artemether-lumefantrine (AL)|DRUG: artesunate-amodiaquine (ASAQ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the In SHAPE Fitness Intervention for Adults With Serious Mental Illness
Status: COMPLETED
Conditions: Schizophrenia|Bipolar Disorder|Schizoaffective Disorder|Major Depressive Disorder
Interventions: BEHAVIORAL: In SHAPE Lifestyles|BEHAVIORAL: Health Club Membership and Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Falls Among the Older Patients Treated for Cancer in Normandy's Outclinics: Screening and Prevention
Status: NOT_YET_RECRUITING
Conditions: Aged Patients Treated for Cancer in Outclinics
Interventions: DIAGNOSTIC_TEST: screening risk for falling and identifiy the risk level low-intermediate-high|DIAGNOSTIC_TEST: 3 mnth-follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effectiveness of Nintendo Wii Fit and Inspiratory Muscle Training in Older Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure|Older People
Interventions: DEVICE: Nintendo Wii Fit|DEVICE: Threshold IMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fermented Milk and Fermented Rice on the Appearance of Respiratory and Gastrointestinal Symptoms
Status: COMPLETED
Conditions: Gastrointestinal Infections|Respiratory Infections
Interventions: DIETARY_SUPPLEMENT: fermented milk|DIETARY_SUPPLEMENT: fermented rice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Prophylactic Decompressive Craniectomy for Poor-grade Aneurysmal Subarachnoid Hemorrhage
Status: UNKNOWN
Conditions: Subarachnoid Hemorrhage, Aneurysmal
Interventions: PROCEDURE: Decompressive craniectomy|PROCEDURE: Best medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Focal Muscular Vibration to Treat Upper Limb Spasticity in Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: FMV_flex|DEVICE: FMV_ext
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Evaluation of an Algorithm for Vascular Access Management
Status: RECRUITING
Conditions: Peripheral Venous Access
Interventions: OTHER: Implementation of the A-DIVA Scale|OTHER: Implementation of the algorithm composed of the A-DIVA Scale and the new decision-making tree (the A-DIVA Tool) in the centers
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Psidii Guava's Extract For COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Extract Psidii guava|COMBINATION_PRODUCT: Standard therapy for Covid-19 patient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Inhaled Nitric Oxide and Oxygen in Participants Reactivity During Acute Pulmonary Vasodilator Testing
Status: COMPLETED
Conditions: Idiopathic Pulmonary Arterial Hypertension|Cardiomyopathy
Interventions: DRUG: Nitric Oxide for inhalation|DRUG: Oxygen|DRUG: Nitric Oxide plus Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Long-term Study of Asenapine in Participants With Residual Subtype, Receiving Multiple or/and High Dose Drugs, or Treatment Refractory Schizophrenia (P06238)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Asenapine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of TAR-302-5018 in Subjects With Neurogenic Detrusor Overactivity Resulting From Spinal Cord Injury
Status: COMPLETED
Conditions: Neurogenic Detrusor Overactivity
Interventions: DRUG: Trospium-Releasing Intravesical System (TAR-302-5018)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Innovative Virtually Supervised Exercise for Dialysis Patients
Status: COMPLETED
Conditions: Diabetes|Chronic Kidney Failure|Hemodialysis Complication
Interventions: OTHER: Sensor-based interactive exercise (game-based exercise)|OTHER: Non-technology foot and ankle exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ultrasound-guided Ipsilateral Transverse Abdominis Plane and Ilioinguinal Iliohypogastric Nerve Block.
Status: COMPLETED
Conditions: Liver Cirrhosis
Interventions: DEVICE: Us guided nerve blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Leflunomide Plus Low Dose Corticosteroid in Immunoglobulin A (IgA) Nephropathy With Renal Insufficiency
Status: UNKNOWN
Conditions: Glomerulonephritis, IGA|Renal Insufficiency, Chronic
Interventions: DRUG: Leflunomide 20 mg+prednisone 0.5mg/kg/d
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Response of Gut Microbiota and Cardiometabolic Biomarkers to Consumption of Walnuts
Status: WITHDRAWN
Conditions: Healthy|Normal Weight|Overweight|Obese
Interventions: OTHER: Walnut|OTHER: Nut-Free
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Pelvic Floor Muscle Training Applied With the Telerehabilitation Method in the Postpartum Period
Status: COMPLETED
Conditions: Pelvic Floor Disorders|Postpartum Disorder|Quality of Life|Mothers
Interventions: OTHER: Pelvic floor muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Lapaquistat Acetate in Subjects With Hypercholesterolemia
Status: TERMINATED
Conditions: Hypercholesterolemia
Interventions: DRUG: Lapaquistat acetate|DRUG: Lapaquistat acetate|DRUG: Lapaquistat acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetes Footcare Companion App for Patients and Carers
Status: COMPLETED
Conditions: Diabetes Mellitus Foot Ulcer|Diabetes Mellitus, Type 2|Diabetic Foot|Diabetic Foot Infection|Ulcer Foot|Ulcer, Leg
Interventions: OTHER: Conversational Agent/Chatbot App
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intravenous Heparin as an Adjunct for the Treatment of Anaphylactic Reactions in an Emergency Department
Status: WITHDRAWN
Conditions: Anaphylaxis
Interventions: DRUG: Intravenous heparin|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT