pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study to Evaluate Efficacy and Tolerability of Two Topical Regimens in Subjects With Moderate to Severe Facial Photodamage Who Have Received Cosmetic Injections
Status: COMPLETED
Conditions: Facial Photodamage
Interventions: OTHER: on-label facial injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1b/2 Platform Study of Select Immunotherapy Combinations in Participants With Advanced Non-small Cell Lung Cancer (NSCLC)
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: S095018|DRUG: S095024|DRUG: S095029|DRUG: S095018 Recommended Dose Expansion (RDE)|DRUG: S095024 RDE|DRUG: S095029 RDE|DRUG: Cemiplimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INvestigating the Lowest Threshold of Vascular bENefits From LDL Lowering With a PCSK9 InhibiTor in healthY Volunteers
Status: COMPLETED
Conditions: Atherosclerosis|Cardiovascular Diseases
Interventions: OTHER: Written Informed Consent|OTHER: Inclusion/Exclusion check|OTHER: Full Clinical Chemistry and Haematology Bloods|OTHER: Serum sample for systemic markers and lipid sub-fractions|OTHER: Pregnancy Test|OTHER: 12 Lead ECG|OTHER: Blood Pressure and Heart Rate|OTHER: Arterial Stiffness|OTHER: Central Haemodynamics|OTHER: Carotid Intima Media Thickness|OTHER: Forearm blood flow studies|OTHER: Concomitant medication check|OTHER: Medication compliance check (Pill count)|OTHER: Physical examination|OTHER: Medical history|OTHER: AE/SAE review & reporting|DRUG: Dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: DSM265 Prophylaxis of Plasmodium Falciparum Malaria
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DSM265|DRUG: Placebo|BIOLOGICAL: Sporozoites|BIOLOGICAL: Infective mosquito bite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Post-Operative Drainage Following Lymph Node Dissection
Status: COMPLETED
Conditions: Malignant Melanoma|Carcinoma, Squamous Cell
Interventions: DRUG: Fibrin Sealant (Tisseel) used in the Experimental Arm.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Temozolomide and Sunitinib Malate in Treating Patients With Stage III or Stage IV Malignant Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: DRUG: sunitinib malate|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Structural and Functional Imaging and Cognitive Functions in Ovarian Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cancer
Interventions: OTHER: Neuroimaging & Neuropsychological Evaluation|OTHER: Neuroimaging & Neuropsychological Evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Examining the Role of Genetics in Determining the Immune Response to an HIV Vaccine in HIV-Uninfected Adult Twins
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: HIV-1 DNA plasmid vaccine|BIOLOGICAL: HIV-1 recombinant Ad5 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Open-label Study Evaluating the Maintenance of Clinical Effect in Adult Schizophrenia Patients Switched From Risperidone Tablets to an Equivalent Dose of a Rapidly-dissolving Tablet Formulation of Risperdone
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Bacteriostatic Saline to Buffered Lidocaine for Ultrasound Guided Hip Joint Injection Local Anesthesia
Status: COMPLETED
Conditions: Hip Pain
Interventions: DRUG: bacteriostatic saline|DRUG: buffered lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Two Dose Levels of Certolizumab Pegol (CZP) in Subjects With Plaque Psoriasis (PSO)
Status: COMPLETED
Conditions: Psoriasis|Plaque Psoriasis
Interventions: BIOLOGICAL: Certolizumab Pegol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lamivudine Therapy in Patients With Prior Entecavir Treatment and Undetectable Viral Load
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Entecavir|DRUG: Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Youth Initiated Mentoring Approach for Juvenile Delinquents
Status: UNKNOWN
Conditions: Juvenile Delinquency|Youth Initiated Mentoring (YIM) Approach
Interventions: BEHAVIORAL: Halt-intervention|BEHAVIORAL: Youth Initiated Mentoring (YIM) approach
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Thoratec HeartMate II Left Ventricular Assist System (LVAS) for Bridge to Cardiac Transplantation
Status: COMPLETED
Conditions: Heart Failure, Congestive|Ventricular Dysfunction|Cardiomyopathies
Interventions: DEVICE: Thoratec HeartMate II Left Ventricular Assist System (LVAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetic Study of MT-3995 at a Low Dose in Subjects With Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: MT-3995|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of Sunitinib In Combination With Cisplatin And 5-Fluorouracil In Patients With Advanced Gastric Cancer
Status: COMPLETED
Conditions: Stomach Neoplasms
Interventions: DRUG: 5-fluorouracil|DRUG: cisplatin|DRUG: sunitinib malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EMPOWIR:Enhance the Metabolic Profile of Women With Insulin Resistance
Status: COMPLETED
Conditions: Hyperinsulinemia|Insulin Resistance|Obesity
Interventions: DRUG: metformin and rosiglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Moxibustion in Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: real moxibustion|DRUG: placebo gel|DRUG: diclofenac sodium gel|OTHER: sham moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Oral Ferric Iron To Treat Iron Deficiency Anaemia in Quiescent Ulcerative Colitis (AEGIS-1)
Status: COMPLETED
Conditions: Iron Deficiency Anaemia|Inflammatory Bowel Disease|Ulcerative Colitis
Interventions: DRUG: ST10-021|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Valproic Acid-Based 2-Agent Oral Regimens for Patients With Advanced Solid Tumor
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Dasatinib|DRUG: Erlotinib|DRUG: Lapatinib|DRUG: Lenalidomide|DRUG: Sorafenib|DRUG: Sunitinib|DRUG: Valproic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tramadol/Diclofenac Fixed-dose Combination Phase III Trial in Acute Pain After Third Molar Extraction
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Tramadol/Diclofenac 50/50|DRUG: Tramadol/Diclofenac 25/25|DRUG: Tramadol 50|DRUG: Diclofenac 50
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Innovative Strategies Which Improve the Clinical Handoff (I-SWITCH)
Status: COMPLETED
Conditions: Healthy
Interventions: BEHAVIORAL: Didactic|BEHAVIORAL: Didactic+Simulation|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evluation of Thyroid Functions in Hemodialysis Childern in Sohag University Hospital
Status: UNKNOWN
Conditions: Chronic Renal Failure
Interventions: DIAGNOSTIC_TEST: thyroid function tests|DIAGNOSTIC_TEST: complete blood count|DIAGNOSTIC_TEST: serum creatinine|DIAGNOSTIC_TEST: blood urea|DIAGNOSTIC_TEST: serum electrolyte|DIAGNOSTIC_TEST: serum calcium|DIAGNOSTIC_TEST: serum phosphorus|DIAGNOSTIC_TEST: parathyroid hormone level|DIAGNOSTIC_TEST: liver function test|DIAGNOSTIC_TEST: arterial blood gases|DIAGNOSTIC_TEST: complete urine analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intervention Study of Drugs in Patients Osteopenia and Osteoporosis
Status: UNKNOWN
Conditions: Osteoporosis|Osteopenia, Osteoporosis
Interventions: OTHER: Basic treatment group|OTHER: Basic treatment+ anti-osteoporosis drug group|OTHER: Basic treatment + non-drug treatment group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neurofeedback Treatment of Affective Instability in Premenstrual Dysphoric Disorder(PMDD)
Status: UNKNOWN
Conditions: Depression|Premenstrual Dysphoric Disorder (PMDD)
Interventions: OTHER: EEG NeuroFeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability, PK and PD of HLX01 in Patients With CD20-positive B-cell Lymphomas
Status: COMPLETED
Conditions: B-cell Lymphomas
Interventions: DRUG: HLX01
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 17-N-Allylamino-17-Demethoxygeldanamycin and Bortezomib in Treating Patients With Relapsed or Refractory Hematologic Cancer
Status: TERMINATED
Conditions: Adult Acute Basophilic Leukemia|Adult Acute Eosinophilic Leukemia|Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Nodal Marginal Zone B-cell Lymphoma|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Small Intestine Lymphoma|Splenic Marginal Zone Lymphoma|Waldenström Macroglobulinemia
Interventions: DRUG: tanespimycin|DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CleanHands Sensor Based System to Improve Hand Hygiene and Reduce Infection
Status: COMPLETED
Conditions: Hand Hygiene|Infection
Interventions: DEVICE: CleanHands System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound-assisted Bilateral Transversus Abdominis Plane Block for Open Prostatectomy
Status: COMPLETED
Conditions: Prostatectomy|Transversus Abdominis Plane Blockade|Pain
Interventions: PROCEDURE: Transversus abdominis plane blockade|PROCEDURE: Morphine-patient-controlled-analgesia-device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Artery DenerVation Clinical Study Using the Gradient Denervation System in Heart Failure Patients With Pulmonary Hypertension Group 2 (PreVail-PH2 Study)
Status: RECRUITING
Conditions: Group 2 Pulmonary Hypertension|Heart Failure
Interventions: DEVICE: Gradient Denervation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: G7 Dual Mobility With Vivacit-E or Longevity PMCF
Status: ENROLLING_BY_INVITATION
Conditions: Hip Osteoarthritis|Rheumatoid Arthritis|Joint Diseases|Avascular Necrosis|Dislocation, Hip|Femoral Neck Fractures|Trochanteric Fractures|Revision Surgeries
Interventions: DEVICE: G7 Dual Mobility with Vivacit-E bearing|DEVICE: G7 Dual Mobility Longevity bearing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Response to the Consumption of Lactobacillus GG and FOS in Patients With Recurrent Herpes Labialis
Status: COMPLETED
Conditions: Herpes Labialis
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Prebiotics|DIETARY_SUPPLEMENT: Prebiotics and Probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of GC1102 (Recombinant Hepatitis B Immunoglobulin) in Chronic Hepatitis B Patients
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: BIOLOGICAL: GC1102
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fc-Engineered Anti-CTLA-4 Monoclonal Antibody in Advanced Cancer
Status: RECRUITING
Conditions: Advanced Cancer|Angiosarcoma|Colorectal Cancer Without Liver Metastases|Endometrial Cancer|Fibrolamellar Carcinoma|Non-small-cell Lung Cancer|Ovarian Cancer|Prostate Cancer
Interventions: DRUG: Botensilimab|DRUG: Balstilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of GWP42004 as Add on to Metformin in the Treatment of Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: GWP42004|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bio Equivalency 20 Mgm Orfadin and 20 Mgm of Nitisonine
Status: UNKNOWN
Conditions: Hereditary Tyrosinemia, Type I
Interventions: DRUG: Nitisinone|DRUG: Orfadin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine With or Without Exatecan Mesylate in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: exatecan mesylate|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Different Types of Platelet Concentrate to Augment Bone Around Immediate Dental Implant
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Implant Failure Nos
Interventions: DRUG: Drug: Growth Factors (CGF)|DRUG: Drug: Growth Factors (PRGF)|PROCEDURE: Surgery: Dental Implant surgery|PROCEDURE: Tooth extraction|PROCEDURE: Xenogenic bone grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Treatment of Depressed Chronic Obstructive Pulmonary Disease Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Major Depression
Interventions: BEHAVIORAL: Treatment Adherence Intervention|BEHAVIORAL: Enhanced Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Supplementation With Immunonutrition and Its Impact on Surgical Outcome and Pain in Oral Cavity or Mandibular Tumours
Status: COMPLETED
Conditions: Immunonutrition|Surgical Outcome|Pain|Oral Cavity|Mandibular Tumor
Interventions: DIETARY_SUPPLEMENT: Standard feeding|DIETARY_SUPPLEMENT: Omega 3 and dipeptiven
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reminder Focused Positive Psychiatry in Adolescents With ADHD and PTSD
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: RFPP|BEHAVIORAL: TFCBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testosterone TRANSdermal Gel for Poor Ovarian Responders Trial
Status: TERMINATED
Conditions: Infertility|Poor Ovarian Response
Interventions: DRUG: Testosterone gel|DRUG: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Stage II or Stage IIIA Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: sargramostim|DRUG: busulfan|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: melphalan|DRUG: paclitaxel|DRUG: tamoxifen citrate|DRUG: thiotepa|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Forced Air Heating to Prevent Hypothermia During Endoscopic Retrograde Cholangiography
Status: RECRUITING
Conditions: Temperature Management During Sedation for Endoscopic Retrograde Cholangiography
Interventions: DEVICE: Forced Air Heating Temperature control "Twinwarm II"
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Diagnostic Validity of the Neurodynamic or Orthopedic Tension Tests
Status: COMPLETED
Conditions: Radiculopathy, Lumbosacral Region
Interventions: DIAGNOSTIC_TEST: Straight Leg Raise test (SLR) and Bragard test (B)|DIAGNOSTIC_TEST: Fajersztajn test (F) and Sicard test (S)|DIAGNOSTIC_TEST: Passive Neck Flexion test (PNF)and Kernig test (K)|DIAGNOSTIC_TEST: Slump test (ST) and Dejerine triad (DT)|DIAGNOSTIC_TEST: MRI scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quantification of Drugs and Their Degradation Products
Status: UNKNOWN
Conditions: Liver Insufficiency|Kidney Failure, Chronic|Obesity|Pregnancy|Breast Feeding, Exclusive|Sepsis|Multiple Organ Failure
Interventions: OTHER: additional blood withdrawals
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: An RCT to Evaluate the Effect of a New Skin Care Regimen on SBF in Those With Podoconiosis
Status: COMPLETED
Conditions: Non-filarial Elephantiasis
Interventions: OTHER: Current skin care regimen plus 2% glycerine added to soaking water|OTHER: Current skin care regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Epidural Fentanyl and Adrenalin During Childbirth
Status: COMPLETED
Conditions: Pregnancy|Pain
Interventions: DRUG: adrenalin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medical and Economical Impact of IGRAs Diagnosis of Latent Tuberculosis in HIV-infected Patients
Status: COMPLETED
Conditions: HIV|Tuberculosis|Latent Tuberculosis Infection
Interventions: OTHER: QTF-TB Gold and T-SPOT TB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Magnetic Field Modulation Pillow for Insomnia Clinical Trial
Status: COMPLETED
Conditions: Insomnia
Interventions: DEVICE: magnetic field modulation device|DEVICE: placebo device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadj ph 2 AI Plus Everolimus in Postmenopausal Women w/ ER Pos/HER2 Neg, Low Risk Score
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Adherence to Spinal Cord Injury Exercise Guidelines Using Smartphone Technology and E-coaching
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: BEHAVIORAL: Stage-I, Group 1: Self monitoring using Non-interactive App|BEHAVIORAL: Stage-I, Group 2: Self monitoring using Interactive App|BEHAVIORAL: Stage-II, Groups 1a/2a: E-Coaching 2x per month|BEHAVIORAL: Stage-II, Groups 1b/2b: E-Coaching 4x per month
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Set-up of a Platform for Personalized Diagnosis of Rare Kidney Diseases (NIKE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: DIAGNOSTIC_TEST: Conclusive genetic testing|DIAGNOSTIC_TEST: Genotype-phenotype correlation for personalized diagnosis|DIAGNOSTIC_TEST: Personalized study of variants of uncertain clinical significance (VUS) through functional studies on 3D organ-on-a-chip
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Aliya™ Pulsed Electric Fields (PEF) for Advanced Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Neoplasm Malignant
Interventions: DEVICE: Aliya Pulsed Electric Fields (PEF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detect V / CHEVENDO (Chemo vs. Endo)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: pertuzumab|DRUG: Trastuzumab|DRUG: Capecitabine|DRUG: Paclitaxel|DRUG: Vinorelbine|DRUG: Docetaxel|DRUG: Exemestane|DRUG: Letrozole|DRUG: Anastrozole|DRUG: Fulvestrant|DRUG: Ribociclib|DRUG: nab-Paclitaxel|DRUG: eribulin|DRUG: leuprorelin|DRUG: goserelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Thorough ECG Study in Subjects With Acne Vulgaris Treated With SB204
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: SB204 4%|DRUG: SB204 8% or 12%|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Flow-controlled Ventilation on Hemodynamic and Respiratory Parameters in Laparoscopic Surgeries
Status: ACTIVE_NOT_RECRUITING
Conditions: Laparoscopic Surgeries
Interventions: DEVICE: flow controlled ventilation|DEVICE: volume controlled ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PFN-A Augmentation for Intertrochanteric Femoral Fractures
Status: COMPLETED
Conditions: Intertrochanteric Fracture
Interventions: PROCEDURE: Cement augmentation|PROCEDURE: PFN-A Nail
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab in Patients With Early-Stage NK/T-cell Lymphoma, Nasal Type
Status: ACTIVE_NOT_RECRUITING
Conditions: NK/T-Cell Lymphoma of Nasal Cavity (Diagnosis)|NK/T-Cell Lymphoma of Nasopharynx (Diagnosis)
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Prospective Thinking in Early Recovery (BEAM)
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: BEHAVIORAL: High-Intensity Cue|BEHAVIORAL: Low-Intensity Cue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of the Suboccipital Inhibition Technique in Forward Head Posture.
Status: NOT_YET_RECRUITING
Conditions: Individuals With Forward Head Posture
Interventions: OTHER: Suboccipital Inhibition Technique|OTHER: Sham Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The STOP-HPV Trial 6: Single Arm Evaluation of the Maintenance of the STOP-HPV Bundle
Status: WITHDRAWN
Conditions: Vaccination|Immunization
Interventions: BEHAVIORAL: The STOP-HPV Trial 6: Maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Apatinib With CDK4/6 Inhibitor and Endocrine Therapy in HR+/ HER2- Advanced Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer Metastatic
Interventions: DRUG: Apatinib|DRUG: Dalpiciclib|DRUG: Fulvestrant/AI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduction of Nocturnal Hypoglycemia and Hyperglycemia in the Home Using Predictive Algorithms, Pump Suspension, and Insulin Dosing in Children and Young Adolescents
Status: COMPLETED
Conditions: Type 1 Diabetes|Hypoglycemia|Hyperglycemia|Artificial Pancreas
Interventions: DEVICE: Hyperglycemia Minimization Algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Intravenous Versus Inhalational Anesthesia in Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: DRUG: Isoflurane|DRUG: Remifentanil|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Bevacizumab Plus 5-Flurouracil (5-FU) Based Doublet Chemotherapy as Neoadjuvant Therapy for Participants With Previously Untreated Unresectable Liver-Only Metastases From Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: 5-FU based doublet chemotherapy|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fibrinogen Replacement to Prevent Intracranial Haemorrhage in Ischemic Stroke Patients After Thrombolysis (FibER)
Status: RECRUITING
Conditions: Intracranial Hemorrhages|Ischemic Stroke
Interventions: DRUG: fibrinogen infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Statin Therapy on Mortality in Patients With Ventilator Associated Pneumonia
Status: COMPLETED
Conditions: VAP - Ventilator Associated Pneumonia
Interventions: DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study to Evaluate the Duration of Effects on Simulated Car Driving and Cognitive Performance After a Single Dose of JNJ-42847922, Zolpidem and Placebo in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-42847922|DRUG: Zolpidem|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating the Safety, Absorption and Elimination of GLPG3312, a New Drug in the Treatment of Inflammatory Diseases
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG3312 IR|DRUG: Placebo|DRUG: GLPG3312 MR|DRUG: GLPG3312 FE MR|DRUG: GLPG3312 MR|DRUG: GLPG3312 MR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Open-label Study of TH-302 and Dexamethasone With or Without Bortezomib or Pomalidomide in Subjects With Relapsed/Refractory Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: TH-302|DRUG: TH-302 and Dexamethasone|DRUG: TH-302 Dose Escalation and Dexamethasone in Combination with Bortezomib|DRUG: TH-302 Dose Escalation and Dexamethasone in Combination with Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EndoVE endosCopic Treatment for Oesophageal and Gastric canceR
Status: COMPLETED
Conditions: Oesophageal Cancer|Oesophageal Disease|Gastric Cancer
Interventions: PROCEDURE: EndoVE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Therapies in Treating Patients With Advanced Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: monoclonal antibody 3F8|BIOLOGICAL: sargramostim|DRUG: carboplatin|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: isotretinoin|DRUG: thiotepa|DRUG: topotecan hydrochloride|DRUG: vincristine sulfate|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: conventional surgery|PROCEDURE: drug resistance inhibition treatment|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: syngeneic bone marrow transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Pre-Pregnancy Supplements
Status: COMPLETED
Conditions: Anemia
Interventions: DIETARY_SUPPLEMENT: Multivitamins, Folic Acid, and Iron|DIETARY_SUPPLEMENT: Folic Acid and Iron|DIETARY_SUPPLEMENT: Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Early Allogeneic Hematopoietic Cell Transplantation in Treating Patients With Relapsed or Refractory High-Grade Myeloid Neoplasms
Status: COMPLETED
Conditions: Blasts 10 Percent or More of Bone Marrow Nucleated Cells|Chronic Myelomonocytic Leukemia-2|High Grade Malignant Neoplasm|Myelodysplastic Syndrome|Myelodysplastic Syndrome With Excess Blasts-2|Myeloid Neoplasm|Previously Treated Myelodysplastic Syndrome|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Cladribine|DRUG: Cyclosporine|DRUG: Cytarabine|BIOLOGICAL: Filgrastim|DRUG: Fludarabine Phosphate|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan|DRUG: Mitoxantrone Hydrochloride|DRUG: Mycophenolate Mofetil|OTHER: Questionnaire Administration|DRUG: Sirolimus|RADIATION: Total-Body Irradiation|DRUG: Melphalan Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Supervision During a Community-based Exercise Intervention (Urban Training) in Patients With COPD
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease|Lung Diseases, Obstructive|Respiratory Tract Diseases
Interventions: BEHAVIORAL: Urban training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Clinical Study of Orelabrutinib in Combination With Rituximab (OR) for Primary Marginal Zone Lymphoma (MZL) That Failed or Not Suitable for Local Therapy
Status: RECRUITING
Conditions: Marginal Zone Lymphoma
Interventions: DRUG: Orelabrutinib in combination with rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sagittal Plane Shear Index for Planning Lumbar Stenosis Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Lumbar Spinal Stenosis|Spondylolisthesis
Interventions: DIAGNOSTIC_TEST: Sagittal plane shear index (SPSI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: NSAID Drug Interaction Study
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: lesinurad 400 mg|DRUG: naproxen 250 mg|DRUG: indomethacin 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy Trial Using Allogeneic Human Mesenchymal Stem Cells: The SIRONA Trial
Status: WITHDRAWN
Conditions: Metabolic Disease|Endothelial Dysfunction
Interventions: BIOLOGICAL: Peripheral Intravenous (IV) infusion of LMSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 1440nm Laser Assisted Selective Photothermolysis for Treatment of Axillary Hyperhidrosis
Status: COMPLETED
Conditions: Hyperhidrosis
Interventions: DEVICE: Nd:YAG 1440 nm laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Bioavailability Study of Extended-release and Immediate-release Trazodone in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Trazodone HCl|DRUG: Trazodone HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of a Computerized Medication Adherence System at Reducing Cardiovascular Disease Risk Factors
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: BEHAVIORAL: Medication Adherence System (MAS)|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of GeneXpert Mycobacterium Tuberculosis/ Rifampicin (MTB/RIF) Versus the Routine Methods for Detection of Mycobacterium Tuberculosis
Status: NOT_YET_RECRUITING
Conditions: Tuberculosis
Interventions: DIAGNOSTIC_TEST: GeneXpert MTB/RIF
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Person-Centered Care Applied to Patients With Dementia on Nutritional Status
Status: ACTIVE_NOT_RECRUITING
Conditions: Dementia
Interventions: BEHAVIORAL: Reminiscence Therapy|BEHAVIORAL: Montessori application|BEHAVIORAL: Environmental Layout|BEHAVIORAL: Application of contrast ergonomic special equipment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of the Pharmacokinetics (PK) and Pharmacodynamics (PD) Biosimilarity of Proposed Biosimilar Rapid-Acting Insulin Aspart (I004) and NovoLog After Single-Dose Subcutaneous Administration to Healthy Volunteers
Status: COMPLETED
Conditions: Pharmacokinetics|Pharmacodynamics
Interventions: DRUG: I004|DRUG: NovoLog
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Study of PF-04360365 In Patients With Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: PF-04360365 10 mg/kg|BIOLOGICAL: PF-04360365 7.5 mg/kg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Repetitive Transcranial Magnetic Stimulation
Status: NOT_YET_RECRUITING
Conditions: Stroke|Mirror Therapy|Transcranial Magnetic Stimulation
Interventions: DEVICE: transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Montelukast in Rhinitis and Sleep
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: montelukast|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sevelamer, Fetuin-A and Endothelial Dysfunction in CKD
Status: COMPLETED
Conditions: Vascular Diseases
Interventions: DRUG: Sevelamer (Renagel), calcium acetate (Phos-ex)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of a New Anti-cancer Immunotherapy in Patients With Non-operable and Progressing Metastatic Cutaneous Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: GSK Biologicals' 2241658A Antigen-Specific Cancer Immunotherapeutic (ASCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ONT-10 and Varlilumab to Treat Advanced Ovarian or Breast Cancer
Status: COMPLETED
Conditions: Advanced Breast Carcinoma|Advanced Ovarian Carcinoma
Interventions: BIOLOGICAL: ONT-10, Varlilumab combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Antihypertensives and Vascular, Endothelial and Cognitive Function Trial
Status: COMPLETED
Conditions: Cognitive Impairment|Hypertension|Aging
Interventions: DRUG: candesartan|DRUG: lisinopril|DRUG: hydrochlorothiazide|DRUG: nifedipine, long acting|DRUG: metoprolol, long-acting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Older Adult Acute Myeloid Leukemia Patients Aged 55 to 65 Years
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Daunorubicin|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Post Tooth Extraction Healing Using Different Xenograft Materials
Status: COMPLETED
Conditions: Alveolar Bone Loss
Interventions: DEVICE: Equimatrix®|DEVICE: Bio-Oss®|DEVICE: Endobon®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Copenhagen Acute Renal Complications After Transplantations Study Group
Status: COMPLETED
Conditions: Disorder Related to Lung Transplantation
Interventions: DRUG: Felodipine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Strategies for Combining the First Component of Sputnik V With Other Adenoviral or mRNA-based Vaccines.
Status: UNKNOWN
Conditions: COVID-19 Vaccines
Interventions: DRUG: Gam-COVID-Vac (rAd26) / Gam-COVID-Vac (rAd5)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Ciclesonide on Exercise Induced Bronchoconstriction
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: ciclesonide|DRUG: ciclesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2 Study of Combination Immunotherapy and Messenger Ribonucleic Acid (mRNA) Vaccine in Subjects With NSCLC
Status: COMPLETED
Conditions: Metastatic Non-small Cell Lung Cancer|NSCLC
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|BIOLOGICAL: BI 1361849|DEVICE: PharmaJet Tropis® device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zynrelef vs Exparel: The Battle of Postoperative Pain Control After Robotic Sleeve Gastrectomy
Status: NOT_YET_RECRUITING
Conditions: Post Operative Pain
Interventions: DRUG: Zynrelef|DRUG: Exparel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Linezolid Alone or Combined With Carbapenem Against Methicillin-resistant Staphylococcus Aureus (MRSA) in Ventilator-associated Pneumonia
Status: UNKNOWN
Conditions: Methicillin-resistant Staphylococcus Aureus|Pneumonia, Ventilator-Associated
Interventions: DRUG: Imipenem/cilastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Carvedilol in Cirrhosis Patients With Uncomplicated Ascites Without High Risk Esophageal Varices
Status: UNKNOWN
Conditions: Liver Cirrhosis
Interventions: DRUG: Carvedilol|DRUG: Standard Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Disc Replacement Versus Anterior Cervical Decompression and Fusion
Status: COMPLETED
Conditions: Cervical Degenerative Disc Disease
Interventions: DEVICE: Surgical treatment of cervical degenerative disc disease (CP ESP®)|DEVICE: Surgical treatment of cervical degenerative disc disease (Axelle®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Acute Effect of Beetroot Juice in Normal and Hypertensive Subjects
Status: COMPLETED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: Beetroot juice|DIETARY_SUPPLEMENT: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Initial Experience With a New Laparoscopic Based Robotically Assisted Surgical System for Cholecystectomy
Status: COMPLETED
Conditions: Biliary Colic|Cholecystitis
Interventions: DEVICE: Senhance Assisted Cholecystectomy|PROCEDURE: Laparoscopic Cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ibuprofen and Erector Spinae Plane Block After Laparoscopic Sleeve Gastrectomy
Status: WITHDRAWN
Conditions: Obesity
Interventions: OTHER: Group ESPB|OTHER: Group Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liposomal Doxorubicin Plus Gemcitabine Versus Oxaliplatin Plus Fluorouracil/Leucovorin for Hepatocellular Carcinoma
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Liposomal Doxorubicin+Gemcitabine|DRUG: FOLFOX4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Shunt vs ETV/CPC for PIH in Ugandan Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Hydrocephalus
Interventions: DEVICE: Chhabra Shunt Placement|PROCEDURE: ETV/CPC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Cognitive Functions and Quality of Life in Patients Undergoing Surgery for Supratentorial Brain Tumor
Status: UNKNOWN
Conditions: Brain Tumor
Interventions: DRUG: Propofol|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cognitive-Behavioral Treatment for Mild Alzheimer's Patients and Their Caregivers
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: BEHAVIORAL: Comprehensive, CBT-based, multi-component treatment|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT