pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of Web-based Education Given to Parents on Children's Internet Gaming Disorder
Status: RECRUITING
Conditions: Internet Gaming Disorder
Interventions: BEHAVIORAL: web-based "I know digital games" training for intervation grup|OTHER: The control group was not trained
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: 12-Week Study of Plecanatide for CIC (The National CIC3 Study)
Status: COMPLETED
Conditions: Chronic Idiopathic Constipation
Interventions: DRUG: Plecanatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Core Strength Training on Wushu C-level Difficulty Movements ,12 Weeks of Core Strength Training
Status: COMPLETED
Conditions: Experimental Myasthenia
Interventions: DEVICE: Wushu athletes in the experimental group used a Swiss ball for 12 weeks of core strength training|DEVICE: Wushu athletes in the experimental group used a balance board for 12 weeks of core strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Study of UTAA06 Injection in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Relapsed/Refractory Acute Myeloid Leukemia
Interventions: BIOLOGICAL: gdT cell injection targeting B7-H3 chimeric antigen receptor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Generalized Training Program for Caregivers on the ESDM: PEGASE
Status: UNKNOWN
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Parental coaching program at ESDM (P-ESDM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: How Astigmatism Influences Corneal Biomechanics and Intraocular Pressure
Status: COMPLETED
Conditions: Corneal Astigmatism|Intraocular Pressure|Cataract Senile
Interventions: DIAGNOSTIC_TEST: non-contact measurement of intraocular pressure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Placebo-controlled Evaluation of Cocculine® Efficacy in the Management of Nausea After Chemotherapy in Breast Cancer.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Cocculine®|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Squamous Cell Carcinoma of the Lung|Merkel Cell Carcinoma|Myxoid/Round Cell Liposarcoma
Interventions: BIOLOGICAL: CAR-GPC3 T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COPD Discharge Bundle Delivered Alone or Enhanced Through a Care Coordinator
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: OTHER: COPD discharge care bundle|OTHER: COPD discharge care bundle & coordinator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Selective Trunk Block vs Hybrid Interscalene Supraclavicular BPB for Anaesthesia of the Entire Upper Extremity
Status: WITHDRAWN
Conditions: Musculoskeletal Diseases or Conditions
Interventions: PROCEDURE: Selective Trunk Block|PROCEDURE: Interscalene-Supraclavicular Brachial Plexus Block (IS-SC BPB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Biolimus-eluting Biodegradable Polymer, Everolimus-eluting and Sirolimus-eluting Coronary Stents
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Promus Element, Boston Scientific Corporation|DEVICE: Nobori, Terumo Corporation (Japan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Dupilumab and Cemiplimab in Patients With Early-stage Resectable NSCLC
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: BIOLOGICAL: Dupilumab|BIOLOGICAL: Cemiplimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Impact of HCV Treatment by Last Generation Direct Antiviral Agents (DAA) on Antiviral Immunity and HIV DNA Reservoir in Coinfected HIV-HCV Patients
Status: UNKNOWN
Conditions: HIV Associated HCV
Interventions: OTHER: blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tissue Glue (Cyanoacrylate) Versus Conventional Suture in Kidney Donors
Status: COMPLETED
Conditions: Skin Closure of Surgical Incisions by Tissue Glue vs Suture
Interventions: PROCEDURE: Skin wound closure by tissue glue|PROCEDURE: Skin wound closure by conventional suture + dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of TKI258 in FGFR1 Amplified and Non-amplified Metastatic HER2 Negative Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: TKI258
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antidepressant Effects of TS-161 in Treatment-Resistant Depression
Status: COMPLETED
Conditions: Major Depressive Disorder|Treatment-Resistant Depression|Depression
Interventions: OTHER: Placebo|DRUG: TS-161 (50 - 100 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Broccoli Sprout Extracts Trial to See if NRF2 is Enhanced by Sulforaphane Treatment in Patients With COPD
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Sulforaphane 25|DIETARY_SUPPLEMENT: Sulforaphane 150|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of the RSV-F Vaccine in Older Adults Previously Treated With the Same Vaccine or Placebo in the Prior Year.
Status: COMPLETED
Conditions: Respiratory Syncytial Virus (RSV)
Interventions: BIOLOGICAL: RSV-F Vaccine|BIOLOGICAL: Phosphate Buffer Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efectivity of Non-invasive Neuromodulation in Parasympathic Nervous System and Vascular System
Status: NOT_YET_RECRUITING
Conditions: Hypertension
Interventions: DEVICE: Non-Invasive neuromodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Of Yoga Before vs After Eccentric Exercise On Delayed Onset Muscle Soreness
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Single bout of yoga before eccentric exercise|OTHER: Single bout of yoga after eccentric exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the Efficacy of a Medical Device in Treatment of Toenail Onychomycosis
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DEVICE: Excilor|DRUG: Loceryl 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postprandial Inflammation and Nuts (PIN) in Older Adults
Status: RECRUITING
Conditions: Healthy Aging|Overweight and Obesity
Interventions: BEHAVIORAL: monounsaturated fatty acids (MUFA) peanut meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Bioequivalence Study Of 80 Mg Atorvastatin Calcium Tablets Versus 80 Mg Lipitor® Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: High Dose IL-2 and Stereotactic Ablative Body Radiation Therapy for Metastatic Renal Cancer
Status: COMPLETED
Conditions: Metastatic Clear Cell Renal Cell Carcinoma
Interventions: DRUG: IL-2|RADIATION: Stereotactic Ablative Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization of Acute Myocardial Damage With Spectral Computed Tomography. (CADAMI-SPECTRAL)
Status: RECRUITING
Conditions: Myocarditis; Acute or Subacute|Takotsubo Cardiomyopathy|Infarction, Myocardial|Myocardial Injury
Interventions: DIAGNOSTIC_TEST: Spectral CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of ADG20 for the Treatment of Mild or Moderate COVID-19
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: ADG20|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TOSCARA Study: A Study of Subcutaneous Tocilizumab (RoActemra/Actemra) in Participants With Active Rheumatoid Arthritis Naïve to RoActemra/Actemra Treatment
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Sufantinib Combined With AG Versus AG First-line in the Treatment of LAPC or mPC
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Neoplasms
Interventions: DRUG: Sofantinib、abraxane、gemcitabine|DRUG: Abraxane combined with gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Bariatric Endoscopic Antral Myotomy (BEAM) as a Treatment for Obesity
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Weight Loss|Delayed Gastric Emptying Following Procedure|Obesity, Mild|Obesity, Morbid|Obesity; Excess Calories
Interventions: PROCEDURE: Bariatric Endoscopic Antral Myotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: a Chronobiological Treatment Combining Evening Melatonin and Morning Light Therapy in Idiopathic Hypersomnia: a Prospective, Double Bind, Randomized, Placebo-controlled -Trial
Status: NOT_YET_RECRUITING
Conditions: Idiopathic Hypersomnia
Interventions: COMBINATION_PRODUCT: - Melatonin - Active light ttherapy|COMBINATION_PRODUCT: - Placebo drug - Placebo light therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Resistance Mechanism of Enterobacteriaceae and Its Strategies
Status: RECRUITING
Conditions: Carbapenem-Resistant Enterobacteriaceae Infection
Interventions: DRUG: CAZ/AVI plus Aztreonam|OTHER: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Semaglutide to Reduce Myocardial Injury in PATIents With COVID-19
Status: UNKNOWN
Conditions: Covid19|Myocardial Injury
Interventions: DRUG: semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Contribution of a Smartphone Application to Acceptance and Commitment Therapy Group Treatment for Smoking Cessation
Status: COMPLETED
Conditions: Smoking
Interventions: BEHAVIORAL: ACT group treatment combined with smartphone application|BEHAVIORAL: ACT group treatment|BEHAVIORAL: Group based Behavioural Support Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: I-Scan For Colon Polyp Detection In HNPCC
Status: COMPLETED
Conditions: Hereditary Non-polyposis Colon Carcinoma|HNPCC|Lynch Syndrome
Interventions: OTHER: The use of I-scan in the detection of polyps in HNPCC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Dural Sinus Stenting of Low Grade Dural Arteriovenous Fistulae (DAVF) for Pulsatile Tinnitus Treatment
Status: NOT_YET_RECRUITING
Conditions: Pulsatile Tinnitus
Interventions: DEVICE: Venous stenting|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suprainguinal Fascia Iliaca (SIFI) Block Improves Analgesia Following Total Hip Arthroplasty
Status: TERMINATED
Conditions: Hip Osteoarthritis|Primary Total Hip Arthroplasty|Pain
Interventions: PROCEDURE: Suprainguinal fascia iliaca (SIFI) block|PROCEDURE: Sham block|DRUG: Ropivacaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nutritional Impact of Moringa Oleifera Leaf Supplementation in Mothers and Children
Status: COMPLETED
Conditions: Malnutrition|Wasting|Growth Failure
Interventions: DIETARY_SUPPLEMENT: Moringa oleifera (high dose)|DIETARY_SUPPLEMENT: Moringa oleifera (low dose)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Genetic Mutational Analysis of Saliva or Buccal Mucosa Samples From Patients With Embryonal or Alveolar Rhabdomyosarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Alveolar Rhabdomyosarcoma|Embryonal Rhabdomyosarcoma
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Laboratory Biomarker Analysis|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Paravalvular Leak After TAVI by Hemodynamic Measurements and Cardiac MRI
Status: ACTIVE_NOT_RECRUITING
Conditions: Transcatheter Aortic Valve Replacement|Hemodynamic Monitoring|Aortic Valve Insufficiency|Aortic Valve Stenosis|Heyde's Syndrome|Acquired Von Willebrand Disease
Interventions: PROCEDURE: cardiac MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Flavopiridol in Treating Patients With Chronic Lymphocytic Leukemia or Prolymphocytic Leukemia
Status: TERMINATED
Conditions: B-cell Chronic Lymphocytic Leukemia|Prolymphocytic Leukemia|Refractory Chronic Lymphocytic Leukemia
Interventions: DRUG: alvocidib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-Hospital Zone 1 Partial Resuscitative Endovascular Balloon Occlusion of the Aorta for Injured Patients With Exsanguinating Sub-diaphragmatic Haemorrhage
Status: COMPLETED
Conditions: Emergencies|Trauma Injury|Trauma, Multiple
Interventions: DEVICE: Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Retrospective Review of DEXTENZA 0.4 mg inseRt Following Corneal Transplant or Cataract Surgery
Status: COMPLETED
Conditions: Anterior Chamber Inflammation|Ocular Pain|Corneal Edema|Corneal Defect|Penetrating KeratoPlasty|Nuclear Cataract|Cortical Cataract|Cataract Senile
Interventions: DRUG: Dextenza 0.4Mg Ophthalmic Insert
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EMG-Based Hand-Wrist Control: Study B Mirrored
Status: COMPLETED
Conditions: Amputation|Amputation; Traumatic, Hand|Amputation, Congenital|Prosthesis User
Interventions: DEVICE: PSICON Measurement Apparatus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Novel Vaccine (EO2463) as Monotherapy and in Combination, for Treatment of Patients With Indolent Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Follicular Lymphoma|Marginal Zone Lymphoma
Interventions: BIOLOGICAL: EO2463|DRUG: lenalidomide|BIOLOGICAL: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HMPL004-6599 Phase I Dose-escalating Study
Status: TERMINATED
Conditions: Ulcerative Colitis|Crohn Disease
Interventions: DRUG: HMPL004-6599|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic Hand on Hand Functions in Strokes
Status: ACTIVE_NOT_RECRUITING
Conditions: CVA (Cerebrovascular Accident)
Interventions: OTHER: Robotic|OTHER: Mirror|OTHER: Traditional Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Action Observation Training for Upper Limb Recovery in Patients With Stroke
Status: COMPLETED
Conditions: Stroke Sequelae
Interventions: BEHAVIORAL: Action Observation Training|BEHAVIORAL: Task Oriented Training|BEHAVIORAL: Conventional Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dexmedetomidine Infusion as an Analgesic Adjuvant During Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: Dexmedetomidine|DRUG: Normal Saline Flush, 0.9% Injectable Solution_#1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-pectoral Breast Reconstruction With or Without Mesh
Status: RECRUITING
Conditions: Prepectoral Breast Reconstruction|TiLOOP Mesh
Interventions: PROCEDURE: prepectoral breast reconstruction|PROCEDURE: Tiloop Mesh implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-Marketing Feasibility Evaluation of the UriCap-RM - Urine Collection in Hospitalized Male Patients
Status: UNKNOWN
Conditions: Urinary Incontinence
Interventions: DEVICE: UriCap-RM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cost Study of Linezolid Versus Vancomycin Among Previously Hospitalized Patients
Status: COMPLETED
Conditions: Complicated Skin and Structure Infection|Nosocomial Pneumonia
Interventions: DRUG: Linezolid|DRUG: Vancomycin|DRUG: Linezolid|DRUG: Vancomycin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Retrospective Chart Review Study to Assess Characteristics, Treatment Outcomes and Resource Use of Adults Hospitalized for CAP and CSSTi Treated With Zinforo in Multiple Countries
Status: COMPLETED
Conditions: Community Acquired Pneumonia|Complicated Skin and Soft Tissue Infection
Interventions: DRUG: Zinforo (ceftaroline fosamil)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Topical 5%Potassium Hydroxide vs Liquid Nitrogen in the Treatment of Plane Warts
Status: COMPLETED
Conditions: Plan Warts
Interventions: DRUG: 5%potassium hydroxide|DRUG: Liquid nitrogen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auricular Stimulation vs. Relaxation for Pre-exam Anxiety
Status: COMPLETED
Conditions: Anxiety
Interventions: DEVICE: Auricular stimulation|BEHAVIORAL: Relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allopurinol for Renal Transplant Associated Hypertension in Children
Status: WITHDRAWN
Conditions: Hypertension|Renal Transplant
Interventions: DRUG: Placebo|DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Nicotinamide/Pterostilbene Supplement in ALS: The NO-ALS Extension Study
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DIETARY_SUPPLEMENT: EH301 (Nicotinamide Riboside/Pterostilbene)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Evaluating Safety and Efficacy of Fluticasone Furoate in People With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone furoate 50mcg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genomic Study of Cutis Tricolor
Status: NOT_YET_RECRUITING
Conditions: Pigmentary; Dermatosis
Interventions: BIOLOGICAL: Blood sample|BIOLOGICAL: Cutaneous biopsy|GENETIC: High troughput sequencing of human's exome
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: IV Acetaminophen for Post-Operative Pain Management in Enhanced Recovery After Surgery (ERAS) Population
Status: COMPLETED
Conditions: Abdominal Wall Hernia|Pancreatic Diseases|Bowel Disease|Gastric Disease
Interventions: DRUG: Acetaminophen Injectable Product|DRUG: Sodium Chloride 0.9%, Intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Panitumumab With or Without Trametinib in Treating Patients With Stage IV Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: EGFR NP_005219.2:p.S492R|KRAS Gene Mutation|MAP2K1 Gene Mutation|Metastatic Colorectal Adenocarcinoma|Refractory Colorectal Adenocarcinoma|Stage IV Colorectal Cancer AJCC v7|Stage IVA Colorectal Cancer AJCC v7|Stage IVB Colorectal Cancer AJCC v7
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Panitumumab|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of A0001 in Subjects With Friedreich's Ataxia
Status: COMPLETED
Conditions: Friedreich's Ataxia
Interventions: DRUG: alpha-tocopherolquinone (A0001)|DRUG: alpha-tocopherolquinone (A0001)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Health Assessment for My Plan: Initial Implementation Study (CHAMP Implementation Study)
Status: NOT_YET_RECRUITING
Conditions: Cancer|Older Adults
Interventions: OTHER: Self-reported online geriatric assessment (CHAMP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy as First-Line Therapy in Treating Older Patients With Metastatic Colorectal Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of 2 Blood Glucose Levels on Hospital Mortality in Patients Admitted in ICU
Status: UNKNOWN
Conditions: Hyperglycemia|Critically Ill Patients
Interventions: OTHER: Strict glycemic control|OTHER: Conventional glycemic control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of BEBT-607 Tablets in The Treatment of Advanced or Metastatic Solid Tumors With KRAS G12C Mutation
Status: RECRUITING
Conditions: Advanced or Metastatic Solid Tumor|KRAS G12C Mutation
Interventions: DRUG: BEBT-607Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Efficacy and Safety Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: CD07805/47 Gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Transcatheter Aortic Valve Implantation and Percutaneous Closure of the Left Atrial Appendage
Status: TERMINATED
Conditions: Aortic Valve Disorder
Interventions: DEVICE: Lotus or ACURATE neo Heart valve system (or subsequent CE marked iterations)|DEVICE: WATCHMAN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Administration of Recombinant Erythropoietin (RHEPO) in Transfusion Savings in Trauma Patients
Status: COMPLETED
Conditions: Trauma
Interventions: OTHER: recombinant erythropoietin injection|OTHER: placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Zonisamide SR Plus Bupropion SR Combination Therapy in Subjects With Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Zonisamide SR placebo/ bupropion SR placebo|DRUG: Zonisamide SR placebo/ bupropion SR 360 mg/day|DRUG: Zonisamide SR 120 mg/day/ bupropion SR placebo|DRUG: Zonisamide SR 360 mg/day/ bupropion SR placebo|DRUG: Zonisamide SR 120 mg/day/ bupropion SR 360 mg/day|DRUG: Zonisamide SR 360 mg/day/ bupropion SR 360 mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of a Compound Glutamine Capsule in the Prevention of Chemotherapy-induced Mucositis
Status: UNKNOWN
Conditions: Mucositis|Chemotherapeutic Toxicity
Interventions: DRUG: a compound glutamine capsule|DRUG: a compound glutamine capsule simulated placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive-Behavioural & Mindfulness-Based Online Programs for Female Sexual Dysfunction
Status: ACTIVE_NOT_RECRUITING
Conditions: Female Sexual Dysfunction
Interventions: BEHAVIORAL: Cognitive-Behavioural Therapy - Online (CBT-O)|BEHAVIORAL: Mindfulness-Based Therapy - Online (MBT-O)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Six-Week Study Evaluating The Efficacy And Safety Of Geodon In Patients With A Diagnosis Of Bipolar I Depression
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Geodon (Ziprasidone)|DRUG: Geodon (Ziprasidone)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Controlled Trial to Compare Single Versus Two Portal Knee Arthroscopy Techniques
Status: TERMINATED
Conditions: Injuries, Knee
Interventions: PROCEDURE: Single Portal Knee Arthroscopy|PROCEDURE: Two Portal Knee Arthroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimized Management of Comorbidity in Heart Failure With Preserved Ejection Fraction in the Elderly (>60 Years)
Status: UNKNOWN
Conditions: Heart Failure, Diastolic
Interventions: OTHER: Screening and treatment of comorbidities|OTHER: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Treatments for Lower Extremity Apophysitis
Status: UNKNOWN
Conditions: Osgood-Schlatter Syndrome|Sinding-Larsen and Johansson Syndrome|Sever's Disease|Apophysitis
Interventions: OTHER: Static Stretch|OTHER: Active Elongation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Immunogenicity of Ad26.RSV.FA2 Followed by Ad35.RSV.FA2 in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Respiratory Syncytial Viruses|Respiratory Tract Infections
Interventions: BIOLOGICAL: Ad26.RSV.FA2|BIOLOGICAL: Ad35.RSV.FA2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Trial for Patients With Metastatic Solid Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Cancer
Interventions: DRUG: Keytruda Injectable Product|DRUG: Yervoy Injectable Product|DRUG: Cytoxan|PROCEDURE: Cryosurgical freezing (cryosurgery)|DRUG: GM-CSF Injectable
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Oral Leukotriene in Long Term Therapy of Mild and Moderate Obstructive Sleep Apnea Syndrome in Children
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DRUG: budesonide (Aircort 50 nasal spray)|DRUG: montelukast (Singulair)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MultiSCRIPT-Cycle 1: Personalized Medicine in Multiple Sclerosis - Pragmatic Platform Trial Embedded Within the SMSC
Status: RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DIAGNOSTIC_TEST: serum Neurofilament Filament Light chain (sNfL) monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Safety and Tolerability of V114 and Prevnar 13™ in Healthy Infants (V114-031/PNEU-LINK)
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: V114|BIOLOGICAL: Prevnar 13™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Longitudinal Comparative Effectiveness of Bipolar Disorder Therapies
Status: TERMINATED
Conditions: Bipolar Disorder
Interventions: DRUG: Lithium Carbonate|DRUG: Lamotrigine|DRUG: Valproic Acid|DRUG: Oxcarbazepine|DRUG: Carbamazepine|DRUG: Ziprasidone|DRUG: Risperidone|DRUG: Quetiapine|DRUG: Olanzapine|DRUG: Aripiprazole|DRUG: Fluoxetine / Olanzapine|DRUG: Haloperidol|DRUG: Perphenazine|DRUG: Clozapine|DRUG: Asenapine|DRUG: Lurasidone|DRUG: Paliperidone|DRUG: Mirtazapine|DRUG: Bupropion|DRUG: Desvenlafaxine|DRUG: Duloxetine|DRUG: Venlafaxine|DRUG: Citalopram|DRUG: Escitalopram|DRUG: Fluoxetine|DRUG: Fluvoxamine|DRUG: Paroxetine|DRUG: Sertraline|DRUG: Vilazodone|DRUG: Doxepin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of NAT-FM Treatment for Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: TAU + multicomponent treatment NAT-FM|BEHAVIORAL: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Tablet Formulation of Dabigatran Etexilate Compared to Commercial Capsule Formulation Following Oral Administration in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: dabigatran etexilate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Usage of Simvastatin in Mild to Moderate Traumatic Brain Injury (TBI) Patients. Could it Make a Difference?
Status: NOT_YET_RECRUITING
Conditions: Traumatic Brain Injury
Interventions: DRUG: Simvastatin|DRUG: Placebo drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Androgen Deprivation Therapy Combined With Docetaxel for High Risk Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoadjuvant Therapy \ High Risk Prostate Cancer \ Docetaxel
Interventions: DRUG: Docetaxel injection|DRUG: Triptorelin Pamoate for Injectable Suspension|DRUG: Prednisone Acetate Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin A in Frequent and Chronic Tension-type Headache
Status: RECRUITING
Conditions: Tension-Type Headache
Interventions: DRUG: Botulinum Toxin Type A in saline water|DRUG: Isotone saline water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Long Haul COVID-19 and Vaccine Immunogenicity in Patients With Liver Disease
Status: RECRUITING
Conditions: COVID-19|Chronic Liver Failure|Cirrhosis, Liver|Portal Hypertension|Liver Transplant Disorder
Interventions: DIAGNOSTIC_TEST: COVID-19 serosurvey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of a Radiolabeled Antibody (7E11) in Patients With Progressive Hormone Refractory Prostate Cancer
Status: UNKNOWN
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: 177Lu-CYT-500
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Safety, Tolerability, Pharmacokinetics, Food Effect and Pharmacodynamics of Single and Multiple Ascending Doses of P7435 in Healthy, Overweight or Obese Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: P7435|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Study Evaluating Efruxifermin in Subjects With Non-invasively Diagnosed Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Nonalcoholic Fatty Liver Disease (NAFLD)/Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Status: RECRUITING
Conditions: NASH/MASH|NAFLD/MASLD
Interventions: DRUG: Efruxifermin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Probiotics PS128 in Movement Disorders
Status: UNKNOWN
Conditions: Rett Syndrome|Tourette Syndrome|Tic Disorders
Interventions: DIETARY_SUPPLEMENT: Probiotic-Lactobacillus plantarum PS128|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II, Open Label, Single Arm Study of SAR302503 In Myelofibrosis Patients Previously Treated With Ruxolitinib
Status: COMPLETED
Conditions: Hematopoietic Neoplasm
Interventions: DRUG: SAR302503
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Kinesio Taping on q Angle and Pes Planus in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Pes Planus
Interventions: OTHER: exercise|OTHER: exercise and taping|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Raltegravir Switch to Resolve Tenofovir Induced Proteinuria
Status: COMPLETED
Conditions: HIV Infections|Proteinuria
Interventions: DRUG: change from tenofovir to raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telescopic Dissection vs. Balloon Dissection During Laparoscopic TEP Inguinal Hernia Repair
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: PROCEDURE: Telescopic Dissection|DEVICE: Balloon Dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: autologous tumor cell vaccine|DRUG: therapeutic autologous dendritic cells|PROCEDURE: tumor cell-derivative vaccine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of the Pharmacokinetics and Safety of Recombinant Factor VIIa Fusion Protein (rVIIa-FP, CSL689) in Patients With Congenital Factor VII Deficiency
Status: COMPLETED
Conditions: Congenital Coagulation Factor VII Deficiency
Interventions: BIOLOGICAL: Eptacog alfa (activated) or pdFVII|BIOLOGICAL: CSL689
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of One-stop Hybrid Revascularization Versus Off-pump Coronary Artery Bypass for the Treatment of Multi-vessel Disease
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Minimally invasive direct coronary artery bypass|PROCEDURE: PCI-Drug eluting stents|PROCEDURE: Off-pump coronary artery bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VXM01 Plus Avelumab Combination Study in Progressive Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Glioblastoma
Interventions: BIOLOGICAL: VXM01|BIOLOGICAL: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Effect of Intensive Statin Therapy in STEMI Patients Before Emergency PCI
Status: UNKNOWN
Conditions: ST-elevation Myocardial Infarction|(STEMI)
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Influence of Tobacco Use on Cannabis Use
Status: SUSPENDED
Conditions: Cannabis Use|Tobacco Use
Interventions: BEHAVIORAL: 7 days of Tobacco Cessation|BEHAVIORAL: 21 days of Tobacco Cessation|DRUG: Cannabis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: To Compare the Pharmacokinetic Characteristics of the Fixed-dose Combination Compared to the Loose Combination
Status: RECRUITING
Conditions: FDC|Diabetes Mellitus, Type 2
Interventions: DRUG: DWC202213|DRUG: DWJ1563|DRUG: DWP16001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Acceptance and Commitment Therapy Self-Help for Carers of People With Multiple Sclerosis
Status: UNKNOWN
Conditions: Carer Stress Syndrome
Interventions: BEHAVIORAL: ACT Self-Help|BEHAVIORAL: ACT Self-Help with Telephone Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Evaluate the Safety, Tolerability, and Efficacy of TMC207 as Part of an Individualized Multi-drug Resistant Tuberculosis (MDR-TB) Treatment Regimen in Participants With Sputum Smear-positive Pulmonary MDR-TB.
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: TMC207|DRUG: Background Regimen (BR) for MDR-TB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amino Acid Supplementation in Recovery From Traumatic Brain Injury
Status: WITHDRAWN
Conditions: Traumatic Brain Injury
Interventions: DIETARY_SUPPLEMENT: Amino Acids|DIETARY_SUPPLEMENT: Placebo of inert compounds|DIETARY_SUPPLEMENT: Valine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of the Combined Intervention of Exercise, Fruit, and Vitamin Supplementation on Frailty in Older Adults
Status: NOT_YET_RECRUITING
Conditions: Frailty
Interventions: BEHAVIORAL: the combined intervention of exercise, fruit, and vitamin supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SMBG Protocols Predicting Glucose Levels in Senior Diabetes Mellitus With CAD
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Coronary Artery Disease
Interventions: BEHAVIORAL: SMBG|OTHER: CGMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Noninvasive Cardiac Imaging in Vasospastic Angina Korean Registry (NAVIGATOR)
Status: UNKNOWN
Conditions: Spasm
Interventions: DIAGNOSTIC_TEST: Spasm positive|DIAGNOSTIC_TEST: Spasm negative
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MTD Determination, Safety and Efficacy of the Decitabine-Genistein Drug Combination in Advanced Solid Tumors and Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: decitabine in combination with genistein
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Atezolizumab in Combination With Either Obinutuzumab Plus Bendamustine or Obinutuzumab Plus (+) Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) in Participants With Follicular Lymphoma (FL) or Rituximab + CHOP in Participants With Diffuse Large B-Cell Lymphoma (DLBCL)
Status: COMPLETED
Conditions: Diffuse Large B-Cell Lymphoma, Lymphoma Follicular
Interventions: DRUG: Atezolizumab|DRUG: Bendamustine|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Obinutuzumab|DRUG: Prednisone|DRUG: Vincristine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maternal Choline Supplementation and Cannabis Use During Pregnancy: Impact on Early Brain Development
Status: NOT_YET_RECRUITING
Conditions: Child Development|Cannabis Use
Interventions: DIETARY_SUPPLEMENT: Placebo|DRUG: Choline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DAPAgliflozin Sodium Water glucosE EffecTs in Patients at High Cardiovascular Risk
Status: RECRUITING
Conditions: Cardiovascular Risk Factor
Interventions: DRUG: Dapagliflozin 10 MG|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III, Study of Three Short Course Combo (Ambisome®, Miltefosine, Paromomycin) Compared With AmBisome for the Treatment of VL in Bangladesh
Status: COMPLETED
Conditions: Visceral Leishmaniasis
Interventions: DRUG: Liposomal amphotericin B|DRUG: liposomal amphotericin B + miltefosine|DRUG: liposomal amphotericin B + paromomycin|DRUG: Miltefosine + Paromomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Premedication With Melatonin on Postoperative Recovery From Bariatric Surgery
Status: COMPLETED
Conditions: Recovery From Bariatric Surgery
Interventions: DRUG: Melatonin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Effects of Vinpocetine in Healthy Adults and Patients With Epilepsy
Status: SUSPENDED
Conditions: Epilepsy
Interventions: DRUG: Vinpocetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of GC1118 (Recombinant Human Anti-EGFR Antibody) in Patients With Advanced Solid Cancer
Status: UNKNOWN
Conditions: Neoplasm Metastasis|Gastric Cancer|Colorectal Cancer
Interventions: BIOLOGICAL: GC1118
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study on HA380 Column Use in Critically Ill Patients Receiving Extracorporeal Support.
Status: NOT_YET_RECRUITING
Conditions: Acute Kidney Injury|ARDS|Inflammation|Extracorporeal Circulation; Complications
Interventions: DEVICE: HA 380
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT