pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Oxytocin and the Processing of Social Stress-Associated Chemosignals
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of a Seven-day BASIS™ Supplementation on Menopausal Syndromes and Measurements of the Urinary Vitamin B3 and Estradiol Levels in Pre-, Peri- and Post-menopause
Status: COMPLETED
Conditions: Menopause
Interventions: DRUG: BASIS™ (Crystalline Nicotinamide Riboside 250mg and Pterostilbene 50mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Hyaluronic Acid ECM on Venous Ulcers
Status: SUSPENDED
Conditions: Venous Ulcers
Interventions: DEVICE: Hyalomatrix extra-cellular matrix|DEVICE: Mepilex wound dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect on Pain and Inflammation With DEXTENZA Treatment in Patients Undergoing Intravitreal Anti-VEGF Injections
Status: TERMINATED
Conditions: Neovascular Age-related Macular Degeneration|Diabetic Macular Edema|Retinal Vein Occlusion
Interventions: DRUG: Dextenza 0.4Mg Ophthalmic Insert|DRUG: Prednisolone Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Allow Access to Imatinib for Patients Who Are on Imatinib Treatment in a Novartis-sponsored Study and Are Benefiting From the Treatment as Judged by the Investigator
Status: ACTIVE_NOT_RECRUITING
Conditions: GIST and CML
Interventions: DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of MRA for Systemic Juvenile Idiopathic Arthritis (sJIA)
Status: COMPLETED
Conditions: Systemic Juvenile Idiopathic Arthritis
Interventions: DRUG: MRA(Tocilizumab)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluorescence Versus Intraoperative Cholangiography in the Visualization of Biliary Tree Anatomy
Status: COMPLETED
Conditions: Cholelithiasis|Gallbladder Polyps
Interventions: DEVICE: Fluorescence cholangiography (da Vinci surgical system)|OTHER: Virtual cholangiography|PROCEDURE: Conventional IOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dose Escalation Study of ALX-009 in Healthy Men and Cystic Fibrosis (CF) and Non-CF Bronchiectasis Patients
Status: TERMINATED
Conditions: Cystic Fibrosis|Bronchiectasis
Interventions: DRUG: ALX-009|DRUG: OSCN-|DRUG: bLF|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Pyrotinib Plus Capecitabine Versus Lapatinib Plus Capecitabine in Patients With HER2+Metastatic Breast Cancer Who Have Prior Received Anthracyclin, Taxane or Trastuzumab
Status: UNKNOWN
Conditions: HER2 Positive Metastatic Breast Cancer
Interventions: DRUG: pyrotinib|DRUG: Lapatinib|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of a New Therapeutic Strategy in the Treatment of Extended-Disease Small-Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Etoposide|DRUG: Carboplatin|DRUG: Bevacizumab|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial of IV Pamidronate for Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DRUG: Pamidronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Peripheral Blood Stem Cell Transplant Followed By Aldesleukin and Sargramostim in Treating Patients With Inflammatory Stage IIIB or Metastatic Stage IV Breast Cancer
Status: COMPLETED
Conditions: Estrogen Receptor-negative Breast Cancer|Estrogen Receptor-positive Breast Cancer|Inflammatory Breast Cancer|Male Breast Cancer|Progesterone Receptor-negative Breast Cancer|Progesterone Receptor-positive Breast Cancer|Stage IIIB Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: tamoxifen citrate|DRUG: busulfan|DRUG: thiotepa|DRUG: melphalan|BIOLOGICAL: aldesleukin|BIOLOGICAL: sargramostim|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studying the Incidence of Erectile Dysfunction in Patients Complaining of Congenital Penile Curvature
Status: COMPLETED
Conditions: To Assess Erectile Function in Patients Complaining of Congenital Penile Curvature
Interventions: DIAGNOSTIC_TEST: Penile Duplex Study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rhomboid Intercostal Block in Cardioverter Defibrillator Implantation (ICD)
Status: RECRUITING
Conditions: Anesthesia|Postoperative Pain|Arrhythmias, Cardiac
Interventions: DEVICE: ultrasound|PROCEDURE: parenteral local anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Immunoglobulin in De-novo CIDP (SIDEC)
Status: RECRUITING
Conditions: CIDP - Chronic Inflammatory Demyelinating Polyneuropathy
Interventions: BIOLOGICAL: Immunoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRaG Therapy in Combination With Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC) (NeoPRAG Study)
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: RADIATION: Radiotherapy|DRUG: Immunotherapy:Granulocyte macrophage-colony stimulating factor(GM-CSF)、Cadumilimab|DRUG: Chemotherapy:Albumin-bound paclitaxel、Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Efficacy of Bilateral Subthalamic Nucleus (SNT) Radiosurgery in Idiopathic Severe Parkinson's Disease Fulfilling Inclusion Criteria for STN Deep Brain Stimulation and Presenting With a Contraindication to Intracerebral Electrode Implantation.
Status: COMPLETED
Conditions: Parkinson's Disease|With Inclusion Criteria for STN Deep Brain Stimulation|Presenting a Contraindication to Intracerebral Electrode Implantati
Interventions: PROCEDURE: Gamma Knife radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Forehead and Frown Lines
Status: COMPLETED
Conditions: Facial Rhytides|Glabellar Frown Lines
Interventions: BIOLOGICAL: botulinum toxin Type A|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacity of rTMS in Alcohol Dependance
Status: COMPLETED
Conditions: Alcohol Dependance
Interventions: OTHER: rTMS (repetitive transcranial magnetic stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myrcludex B Plus Pegylated Interferon-alpha-2a in Patients With HBeAg Negative HBV/HDV Co-infection
Status: COMPLETED
Conditions: Chronic Hepatitis D Infection
Interventions: DRUG: PEG IFN alfa-2a|DRUG: Myrcludex B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ondansetron Use for Preventing Pruritus In Patients Undergoing Cesarean Section
Status: NOT_YET_RECRUITING
Conditions: Pruritus Caused by Drug
Interventions: DRUG: Ondansetron 8mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation of Low Risk Papillary Thyroid Microcarcinoma
Status: RECRUITING
Conditions: Papillary Thyroid Microcarcinoma|Thyroid Cancer
Interventions: PROCEDURE: RFA for PTMC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Internet and In-Person Brief Cognitive Behavioral Therapy of Insomnia
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: In-person Cognitive Behavioral Therapy of Insomnia|BEHAVIORAL: Internet Cognitive Behavioral Therapy of Insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Zinc Supplementation as an Adjuvant to Topical Corticosteroid in Oral Lichen Planus Patients
Status: UNKNOWN
Conditions: Oral Lichen Planus
Interventions: DRUG: Oral Zinc supplementation|DRUG: Oral placebo supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of 1 8F-FDHT PET/MRIScans in Women With Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer|Breast Carcinoma|Metastatic Breast Cancer|Metastatic Breast Carcinoma|Female Breast Cancer
Interventions: DIAGNOSTIC_TEST: 18F-FDG PET/CT|DIAGNOSTIC_TEST: [18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone PET Imaging|DRUG: 18F-FDHT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Quick-Wee Versus Bladder Stimulation System to Collect Midstream Urine From Pre-continent Infants
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: OTHER: bladder stimulation|OTHER: Quick wee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: L-Carnitine to Treat Fatigue in AIDS Patients
Status: COMPLETED
Conditions: HIV Infections|AIDS
Interventions: DRUG: L-carnitine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact Ureteral Sheath Design During Ureteroscopy
Status: COMPLETED
Conditions: Renal Stone|Nephrolithiasis|Urolithiasis
Interventions: DEVICE: Cook Flexor|DEVICE: Boston Scientific Navigator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Lowering PEEP: Weaning From High PEEP Setting
Status: COMPLETED
Conditions: Mechanical Ventilation Complication
Interventions: OTHER: decrease the positive end expiratory pressure (PEEP)|OTHER: mechanical features assessment|OTHER: shunt assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic, Safety/Tolerability Study of a Single SC Dose of PB1023 Injection in Subjects With Normal and Impaired Renal Function
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: PB1023 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study to Compare CMAB818 Injection and Lucentis® in Patients With Wet AMD
Status: COMPLETED
Conditions: Wet Age-related Macular Degeneration
Interventions: DRUG: CMAB818|DRUG: Lucentis®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bronchial Artery Embolization and Medical Measures in Non Severe Acute Hemoptysis of Mild-moderate Abundance
Status: COMPLETED
Conditions: Hemoptysis|Acute Disease
Interventions: OTHER: Medicals measures|OTHER: bronchial artery embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Chemotherapy Plus Bone Marrow Transplantation and Filgrastim in Treating Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: BIOLOGICAL: filgrastim|DRUG: busulfan|DRUG: etoposide|PROCEDURE: autologous bone marrow transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Retrieval Practice and Schizophrenia
Status: SUSPENDED
Conditions: Schizophrenia|Episodic Memory Deficits
Interventions: BEHAVIORAL: Retrieval practice effect using descriptive stories and free-call tests without feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Systolic Hypertension in the Elderly Program (SHEP) (Pilot Study)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Hypertension|Vascular Diseases
Interventions: DRUG: chlorthalidone|DRUG: reserpine|DRUG: hydralazine|DRUG: metoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With Primary Immune Thrombocytopenia
Status: NOT_YET_RECRUITING
Conditions: Primary Immune Thrombocytopenia (ITP)
Interventions: BIOLOGICAL: Efgartigimod IV|OTHER: Placebo IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Inspiratory Muscle Training on Posture in Chronic Obstructive Pulmonary Disease Patients
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Targeting Orexin to Treat Nicotine Dependence
Status: RECRUITING
Conditions: Nicotine Dependence
Interventions: DRUG: Suvorexant 20 mg|DRUG: Suvorexant 10 mg|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Determine the Safety, Tolerability, and Efficacy of MAU868 for the Prevention of BK Virus Infection in Kidney Transplant Recipients
Status: WITHDRAWN
Conditions: BK Virus Nephropathy
Interventions: BIOLOGICAL: MAU868|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nasal HFOV Versus Nasal CPAP to Reduce Post-extubation pCO2
Status: TERMINATED
Conditions: Respiratory Distress Syndrome, Newborn|Respiratory Tract Diseases
Interventions: DEVICE: nHFOV|DEVICE: nCPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of SPY Fluorescent Angiography to Reduce Ureteroenteric Stricture Rate Following Urinary Diversion
Status: ENROLLING_BY_INVITATION
Conditions: Ureteral Obstruction|Stricture Ureter
Interventions: DEVICE: SPY fluorescent angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Evaluation of Baofeikang Granule in Combined Pulmonary Fibrosis and Emphysema Treatment
Status: UNKNOWN
Conditions: Combined Pulmonary Fibrosis and Emphysema
Interventions: DRUG: Baofeikang Granule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Azacitidine Combined With Interferon in the Treatment of Post-transplant Recurrence
Status: UNKNOWN
Conditions: HSCT|Efficacy and Safety
Interventions: DRUG: Azacitidine combined with interferon preemptive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin Hydrochloride, Cisplatin, and Paclitaxel or Carboplatin and Paclitaxel in Treating Patients With Stage III-IV or Recurrent Endometrial Cancer
Status: COMPLETED
Conditions: Recurrent Uterine Corpus Carcinoma|Stage IIIA Uterine Corpus Cancer AJCC v7|Stage IIIB Uterine Corpus Cancer AJCC v7|Stage IIIC Uterine Corpus Cancer AJCC v7|Stage IVA Uterine Corpus Cancer AJCC v7|Stage IVB Uterine Corpus Cancer AJCC v7
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Doxorubicin Hydrochloride|BIOLOGICAL: Filgrastim|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|BIOLOGICAL: Pegfilgrastim|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of ASC-J9 Cream in Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: ASC-J9 cream|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Traditional Massage on Spasticity and Activity of Children(2 to 10 Years) With Cerebral Palsy
Status: UNKNOWN
Conditions: Cerebral Palsy, Spastic, Diplegic
Interventions: OTHER: Intervention Group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Safety, Tolerability and Pharmacokinetics Study in Adult Patients With Schizophrenia Following Administration of Aripiprazole IM Depot
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: aripiprazole IM depot|DRUG: aripiprazole tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Stable Isotope Study to Evaluate the Bioavailability of an Oat Protein-based Iron Delivery System
Status: COMPLETED
Conditions: Bioavailability
Interventions: OTHER: 54Fe SO4|OTHER: 57Fe Oat-1|OTHER: 58Fe Oat-2|OTHER: 54 FeSO4 + Acai puree with honey|OTHER: 57Fe Oat-1 + Acai puree with honey|OTHER: 58Fe Oat-2 + Acai puree with honey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Antenatal Breastmilk Expression From Week 34 of Gestation
Status: COMPLETED
Conditions: Breastmilk Expression|Collection, Breastmilk|Breastfeeding|Healthy
Interventions: BEHAVIORAL: Antenatal breastmilk expression|BEHAVIORAL: Breastfeeding consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Novel Determinants and Measures of Smokeless Tobacco Use: Study 2
Status: COMPLETED
Conditions: Tobacco Use Disorder|Nicotine Dependence
Interventions: OTHER: Low nicotine|OTHER: Medium nicotine|OTHER: High nicotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab for Nasopharyngeal Carcinoma Patients With Detectable Plasma Epstein-Barr Virus DNA
Status: TERMINATED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Everolimus Plus Rituximab for Relapsed/Refractory Diffuse Large B Cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Everolimus|DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation Assessment and Clinical Utility of the FilmArray® Respiratory Panel (RP) EZ in a CLIA-waived Setting
Status: COMPLETED
Conditions: Respiratory Tract Infections
Interventions: DEVICE: FilmArray RP EZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bladder Management in Patients With Multiple Sclerosis: Optimizing Practice Patterns
Status: COMPLETED
Conditions: Multiple Sclerosis|Urinary Bladder Diseases
Interventions: BEHAVIORAL: Systematic Screening and Education Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of CPL-2009-0031 in the Treatment of Patients With Uncontrolled Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Uncontrolled Type 2 Diabetes Mellitus
Interventions: DRUG: CPL-2009-0031 140 mg|DRUG: Sitagliptin 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Burch Urethropexy and Mid-urethral Sling Performed Concomitantly With a Sacral Colpopexy
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: PROCEDURE: Burch urethropexy|PROCEDURE: Synthetic mid-urethral sling (TVT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Losartan/Chlorthalidone vs Losartan/Hydrochlorothiazide in Essential Arterial Hypertension
Status: COMPLETED
Conditions: Essential Arterial Hypertension
Interventions: DRUG: Losartan/Chlorthalidone in fixed dose|DRUG: Losartan + hydrochlorothiazide in fixed dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Abuse Potential of Dronabinol in Recreational Cannabinoid Users
Status: COMPLETED
Conditions: Drug Abuse, Medication
Interventions: DRUG: Dronabinol 10 mg|DRUG: Dronabinol 30 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Demethylating Agent Azacitidine on Prevention of Acute Kidney Injury-chronic Kidney Disease Continuum
Status: UNKNOWN
Conditions: Acute Kidney Disease
Interventions: DRUG: Azacitidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Radiation Therapy Following Surgery in Treating Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: cisplatin|DRUG: paclitaxel|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Comparison of Two Daily Wear Frequent Replacement Silicone Hydrogel Soft Contact Lenses
Status: COMPLETED
Conditions: Refractive Errors|Ametropia
Interventions: DEVICE: Lehfilcon A contact lenses|DEVICE: Senofilcon A contact lenses|DEVICE: Comfilcon A contact lenses|DEVICE: Hydrogen peroxide-based cleaning and disinfecting solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nepafenac 0.3% Two Study
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Nepafenac Ophthalmic Suspension, 0.3%|DRUG: Nepafenac Ophthalmic Suspension, 0.1%|OTHER: Nepafenac Vehicle 0.3%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Association Between Hyponatremia and Osteoporosis in Patients With Epilepsy.
Status: COMPLETED
Conditions: Hyponatremia|Metabolic Bone Disease
Interventions: DRUG: Sodium chloride|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Ultrasound-guided Erector Spinae Plane Block and Transmuscular Quadratus Lumborum Block
Status: NOT_YET_RECRUITING
Conditions: Colo-rectal Cancer
Interventions: OTHER: nerve blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of D-allulose on Weight and Fat Loss and Insulin Resistance in Non-diabetic Obese Subjects
Status: UNKNOWN
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: D-allulose|DIETARY_SUPPLEMENT: erythritol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-Articular Catheter Total Knee Arthroplasty
Status: NOT_YET_RECRUITING
Conditions: Continuous Local Infiltration Analgesia|Intra-articular Catheter|Total Knee Arthroplasty
Interventions: DEVICE: Intra-articular catheter|OTHER: Routine Standard of Care Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Evaluating the Role of Oral Antibiotics in an Aim to Eradicate Carrier State of Carbapenem- Resistant Klebsiella Pneumonia (KPC).
Status: COMPLETED
Conditions: Klebsiella Pneumoniae Carbapenemase Resistant Associated Bacteremia or Pneumonia
Interventions: DRUG: Colistin (Polymyxin E) 100mg x 4/d|DRUG: both medications|DRUG: will not receive PO treatment|DRUG: PO Garamycin 80mg x 4/d
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zinc Intervention in Elderly for Prevention of Pneumonia
Status: COMPLETED
Conditions: Zinc Deficiency
Interventions: DRUG: Zinc gluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prebiotics and Immune Function in Middle Aged Humans
Status: COMPLETED
Conditions: Immune Function
Interventions: DIETARY_SUPPLEMENT: Prebiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Celecoxib Compared With No Treatment Before Surgery in Treating Patients With Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: celecoxib|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: First-in-man Study of Adult Patients Suffered From Alveolar Osteitis Treated Using Stomatological Tamponade Contipro
Status: COMPLETED
Conditions: Alveolar Osteitis
Interventions: DRUG: Stamatological tamponade Contipro
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: H-coil TMS to Reduce Pain: A Pilot Study Evaluating Relative Efficacy of the H1 vs H7 Coil
Status: TERMINATED
Conditions: Healthy|Chronic Pain|Opioid Use|Pain, Chronic
Interventions: DEVICE: Real rTMS to the mPFC using H7 Coil|DEVICE: Real rTMS to the dlPFC using H1 Coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Ultra Violet-C Light Evaluation as an Adjunct to Removing Multi-Drug Resistant Organisms (UVCLEAR-MDRO)
Status: COMPLETED
Conditions: Healthcare Associated Infection|Multidrug Resistant Organisms
Interventions: OTHER: UV-C light disinfection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combustion Derived Air Pollution and Vascular Function
Status: COMPLETED
Conditions: Endothelial Dysfunction
Interventions: PROCEDURE: Forearm Vascular Study|PROCEDURE: Badimon Chamber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: 3D Printed Scaffold Device for Ridge Preservation After Tooth Extraction
Status: COMPLETED
Conditions: Bone Resorption After Tooth Extraction
Interventions: DEVICE: PCL-TCP scaffold|DEVICE: Geistlich Bio-Gide collagen membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess PK, Safety and Tolerability in Healthy Subjects
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: QHRD106 Injection|DRUG: Human Urinary Kallidinogenase|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Escitalopram Treatment of Major Depression in Patients With Temporal Lobe Epilepsy
Status: COMPLETED
Conditions: Major Depression|Temporal Lobe Epilepsy
Interventions: DRUG: escitalopram|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Randomized, Double-Blind, Placebo-Controlled Study of Acellular and Whole-Cell Pertussis Vaccines
Status: COMPLETED
Conditions: Pertussis
Interventions: BIOLOGICAL: whole-cell pertussis vaccine|BIOLOGICAL: diphtheria-tetanus vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Transition to Cardiac Rehabilitation (T2CR) to Address Barriers of Multimorbidity and Frailty
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases|Cardiac Rehabilitation|Transition of Care
Interventions: BEHAVIORAL: T2CR Intervention|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigational Drug Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-801)
Status: COMPLETED
Conditions: Hypercholesterolemia|Coronary Disease
Interventions: DRUG: MK0653, ezetimibe|DRUG: Comparator: ezetimibe, placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Letrozole Plus Metronomic Capecitabine as First-line Treatment for Patients With Recurrent or Metastatic Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Metastasis Breast
Interventions: DRUG: letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of a New Drug, Nirogacestat, for Treating Desmoid Tumors That Cannot be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Desmoid Fibromatosis|Recurrent Desmoid Fibromatosis|Unresectable Desmoid Fibromatosis
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Nirogacestat|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Effects of Pressure-regulated Volume Control Mode in Patients With Diastolic Dysfunction Undergoing Radical Cystectomy
Status: COMPLETED
Conditions: Radical Cystectomy
Interventions: DEVICE: pressure regulated volume-controlled mode of ventilation|DEVICE: volume-controlled mode of ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Prevention of Acute Radiation Enteritis With Glutamine
Status: COMPLETED
Conditions: Acute Radiation Enteritis
Interventions: DIETARY_SUPPLEMENT: Glutamine|DIETARY_SUPPLEMENT: Whole protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Methadone in Post-Herpetic Neuralgia Pain
Status: COMPLETED
Conditions: Post-herpetic Neuralgia
Interventions: DRUG: Methadone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Isatuximab, Carfilzomib, and Pomalidomide for the Treatment of Relapsed or Refractory Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: DRUG: Carfilzomib|BIOLOGICAL: Isatuximab|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intestinal Ultrasound for the Evaluation of Pouchitis and Other Outcomes After Ileal Pouch-Anal Anastomosis
Status: RECRUITING
Conditions: Ulcerative Colitis|Pouchitis
Interventions: DIAGNOSTIC_TEST: Intestinal Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effectiveness and Mechanism of Character Strengths-based STEP Programme on Rehabilitation of Stroke Patients
Status: RECRUITING
Conditions: Stroke|Intervention|Rehabilitation|Depression
Interventions: OTHER: Character strengths-based structured treatment and education programme (CSSTEP)|OTHER: Structured treatment and education programme (STEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Antibacterial Effect of Miswak Toothpaste Compared to Fluoride Toothpaste
Status: UNKNOWN
Conditions: Caries
Interventions: OTHER: Miswak toothpaste|OTHER: Fluoride toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Gemifloxacin Versus Intravenous Cefotaxime in Treatment of Spontaneous Bacterial Peritonitis
Status: RECRUITING
Conditions: Spontaneous Bacterial Peritonitis
Interventions: DRUG: Cefotaxime|DRUG: Gemifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Involvement of Transverso-sacral- Neo- Articulations or of Transverso-iliac Articulations in Chronic Lumbago
Status: TERMINATED
Conditions: Subjects Suffering of Lateralized Lumbago on Side of the Malformation (Neo-articulation)
Interventions: DRUG: corticoid (altim® 1.5 ml)|DRUG: physiological solution (1.5 ml)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lifestyle-related Early Detection and Intervention for Older Adults & Elderly at Risk for Metabolic Syndrome
Status: UNKNOWN
Conditions: Metabolic Syndrome
Interventions: BEHAVIORAL: Standard care|BEHAVIORAL: Health-promotion application for self-management|DEVICE: Wearables and devices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Study: Combining Nutritional Supplements With Standard Antidepressant to Treat Depression.
Status: WITHDRAWN
Conditions: Depression
Interventions: DIETARY_SUPPLEMENT: L-tyrosine|DIETARY_SUPPLEMENT: L-Tryptophan|DRUG: deplin|OTHER: Placebo A|OTHER: Placebo B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study of Arzoxifene to Treat Korean Women With Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: arzoxifene|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Probiotic Strain Lactobacillus Paracasei K56 on Metabolic Symptom - a Pilot Study
Status: COMPLETED
Conditions: Obesity|Adiposity
Interventions: DIETARY_SUPPLEMENT: probiotic drink with Lactobacillus paracasei K56|DIETARY_SUPPLEMENT: maltodextrin|DIETARY_SUPPLEMENT: Probiotic powder E3|DIETARY_SUPPLEMENT: Probiotic powder E5|DIETARY_SUPPLEMENT: probiotic capsule E7|DIETARY_SUPPLEMENT: probiotic capsule E9|DIETARY_SUPPLEMENT: probiotic capsule E10|DIETARY_SUPPLEMENT: probiotic capsule E11
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ABOD2011 in Patients With Advanced Solid Tumors Progressed After Standard Systemic Therapy
Status: RECRUITING
Conditions: Patients With Advanced Solid Tumors
Interventions: BIOLOGICAL: human single chain IL-12 mRNA-single dose|BIOLOGICAL: human single chain IL-12 mRNA-multiple dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of PRP & DFDBA vs. DFDBA in Intrabony Periodontal Defects
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: OTHER: PRP combined with DFDBA|OTHER: DFDBA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Ambroxol Lozenge 20 mf in Relieving Pain of Sore Throat in Pat. With Acute/Viralpharyngitis
Status: COMPLETED
Conditions: Pharyngitis
Interventions: DRUG: Ambroxol hydrochloride (Mucoangin?)|DRUG: benzocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Submucosal Dissection Combine With Laparoscopic Regional Lymph Node Dissection for Early Gastric Cancer
Status: UNKNOWN
Conditions: Early Gastric Cancer
Interventions: PROCEDURE: ESD AND LRLD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of JNJ-39393406 on Event Related Potentials in Stable Schizophrenic Patients
Status: TERMINATED
Conditions: Schizophrenia|Alzheimer's Disease|Cognition Disorders
Interventions: DRUG: JNJ-39393406|DRUG: placebo|DRUG: JNJ-39393406|DRUG: JNJ-39393406|DRUG: JNJ-39393406|DRUG: JNJ-39393406
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Microcrystalline Titanium Dioxide With Covalently Linked Monovalent Silver Ions on Complications After Total Hysterectomy
Status: UNKNOWN
Conditions: Infection|Bleeding|Complication, Postoperative
Interventions: OTHER: TIAB: microcrystalline titanium dioxide with covalently linked monovalent silver ions|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Low Level Laser Therapy Effect on Treatment Outcomes of Bony Supported Distal Jet for Correction of Angle Class II Malocclusion (Randomized Clinical Trial)
Status: RECRUITING
Conditions: This Study Focus on the Effect of Low-Level Light Therapy on the Amount of Upper Molar Distalization
Interventions: RADIATION: low level laser therapy|DEVICE: bonny supported distal jet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Faecal Microbiota Transplantation in Patients With IBS
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: healthy feces microbiota
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Socioeconomic and Environmental Factors on the Natural History of Idiopathic Pulmonary Fibrosis
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis|Pulmonary Disease|Pulmonary Medicine
Interventions: DIAGNOSTIC_TEST: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study Comparing Standard Dose and High-dose Imatinib Mesylate in Patients With Chronic Phase Philadelphia Chromosome Positive (Ph+) Chronic Myelogenous Leukemia (CML)
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia
Interventions: DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dolutegravir Interactions With Artemisinin-based Combination Therapies
Status: COMPLETED
Conditions: Malaria|HIV
Interventions: DRUG: Dolutegravir 50mg od|DRUG: Artemether-lumefantrine combination|DRUG: Artesunate-amodiaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome of TAMIS Mucosal Resection in Patients With ODS
Status: COMPLETED
Conditions: Constipation, Impaction, and Bowel Obstruction|TAMIS Mucosectomy|Obstructed Defecation Syndrome
Interventions: PROCEDURE: TAMIS mucosectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MRX-2843 and Osimertinib for the Treatment of Advanced EGFR Mutant Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Advanced Lung Non-Small Cell Carcinoma|Metastatic Lung Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: DRUG: Flt3/MerTK Inhibitor MRX-2843|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Feasibility of the Individualized Positive Psychosocial Intervention (IPPI)
Status: ENROLLING_BY_INVITATION
Conditions: Dementia|Depression|Behavior
Interventions: BEHAVIORAL: Individualized Positive Psychosocial Interaction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Targeted Drug Combined With CHOP in the Treatment of Newly Diagnosed Peripheral T-cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: CHOP|DRUG: CHOP+X
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surviving Opioid Overdose With Naloxone Education and Resuscitation Trial (SOONER)
Status: WITHDRAWN
Conditions: Opioid Use|Opioid-Related Disorders|Opioid Withdrawal|Opioid Overdose|Education|Resusitation
Interventions: OTHER: SOONER Video & Kit|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase III Study of Two Different Schedules (Weekly and Tri-weekly) of Combination of Gemcitabine and Two Taxanes in MBC
Status: COMPLETED
Conditions: Metastatic Breast Cancer (MBC)
Interventions: DRUG: Gemcitabine|DRUG: Docetaxel|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BCAA in Patients Undergoing Gastric Cancer Surgery
Status: NOT_YET_RECRUITING
Conditions: Perioeprative Muscle Loss
Interventions: DIETARY_SUPPLEMENT: BCAA|OTHER: patient not administered BCAA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Positive Airway Pressure for the Treatment of Asthma
Status: COMPLETED
Conditions: Asthma|Sleep Apnea
Interventions: DEVICE: Bilevel PAP (4 weeks)|OTHER: Usual Care (4 weeks)|OTHER: Washout Period (4 weeks)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quit For Life (QFL): Smoking Cessation Among Chinese Smokers Living With HIV
Status: COMPLETED
Conditions: Smoking Cessation|HIV Infections
Interventions: BEHAVIORAL: Sessions with a trained counselor|OTHER: Cell phone messages|OTHER: Offered nicotine replacement therapy|OTHER: Self-help guide for quitting smoking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT