pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Procalcitonin and Postoperative Outcome After Open-heart Surgery
Status: COMPLETED
Conditions: Open Heart Surgery|Cardiopulmonary Bypass|Procalcitonin|C-reactive Protein|Lactate|Outcome|Postoperative Complications
Interventions: DIAGNOSTIC_TEST: Serum levels of Procalcitonin, C-reactive protein, lactate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transcutaneous Electrical Acupoint Stimulation on Symptoms Associated With Chemotherapy Induced Peripheral Neuropathy
Status: NOT_YET_RECRUITING
Conditions: Breast Neoplasms|Chemotherapy-induced Peripheral Neuropathy
Interventions: DEVICE: Transcutaneous Electrical Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Hybrid Rapid Maxillary Expander Assisted With Micro-osteo Perforation (MOPs) in Adult.
Status: NOT_YET_RECRUITING
Conditions: Maxillary Anomaly
Interventions: PROCEDURE: hybrid rapid maxillary expander assisted with Micro-osteo perforation (MOPs)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial Testing The Efficacy Of Crizotinib Versus Standard Chemotherapy Pemetrexed Plus Cisplatin Or Carboplatin In Patients With ALK Positive Non Squamous Cancer Of The Lung
Status: COMPLETED
Conditions: Non Squamous Lung Cancer
Interventions: DRUG: treatment|DRUG: treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Tumor Associated Cell-free DNA in Peritoneal Fluid Obtained by Culdocentesis
Status: TERMINATED
Conditions: Stage III Ovarian Cancer|Stage IV Ovarian Cancer
Interventions: PROCEDURE: Culdocentesis|PROCEDURE: Vaginal Swab|PROCEDURE: Chromopertubation|PROCEDURE: Blood collection|PROCEDURE: Tissue collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Post-operative Pain Control After Pediatric Adenotonsillectomy
Status: TERMINATED
Conditions: Recurrent Tonsillitis|Obstructive Sleep Apnea|Sleep Disordered Breathing|Adverse Reaction to Drug
Interventions: DRUG: Ibuprofen|DRUG: Hydrocodone-Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy of Mesalamine in the Long-term Prevention of Diverticulitis Flares
Status: COMPLETED
Conditions: Diverticular Disease
Interventions: DRUG: mesalamine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Worksite Wellness Randomized Controlled Trial
Status: COMPLETED
Conditions: Obesity|Overweight|Quality of Life
Interventions: BEHAVIORAL: The iDiet® (also called Healthy Weight for Living when used as a not-for-profit intervention) with Food|BEHAVIORAL: The iDiet® (also called Healthy Weight for Living when used as a not-for-profit intervention) with Voucher|BEHAVIORAL: Human Performance Institute©
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intra Muscular Electrotherapy Combined With Manipulative Therapy in Patients With Sacral Torsion
Status: RECRUITING
Conditions: Sacroiliac Joint Dysfunction
Interventions: PROCEDURE: Physical Agents|PROCEDURE: Manipulation|PROCEDURE: Core Stability Exercises|PROCEDURE: Intramusular electrotherapy|PROCEDURE: Soft tissue mobility
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Bev Plus DOF vs DOF in LAGC and Its Association With Circulating Tumor Cell
Status: COMPLETED
Conditions: Locally Advanced Gastric Carcinoma
Interventions: BIOLOGICAL: Bevacizumab|DRUG: docetaxel oxaliplatin 5-FU CF|PROCEDURE: Gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2b Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)
Status: RECRUITING
Conditions: Thyroid Eye Disease|Graves Orbitopathy|Endocrine System Diseases|Eye Diseases|Thyroid Associated Ophthalmopathy|Graves Ophthalmopathy|Thyroid Diseases|Orbital Diseases|Proptosis|IGF1R|Exophthalmos|Hashimoto
Interventions: DRUG: linsitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: WALANT Versus Axillary Brachial Plexus Block in Carpal Tunnel Release
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: BAX|PROCEDURE: Tourniquet|DRUG: Lidocaine|PROCEDURE: WALANT|DRUG: Lidocaine + Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Inspiratory Muscle Training on Shortness of Breath (Dyspnea) and Postural Control in Patients With COPD
Status: COMPLETED
Conditions: Copd|Inspiratory Muscle Weakness
Interventions: PROCEDURE: Inspiratory Muscle Strength Training|PROCEDURE: Inspiratory Muscle Endurance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label, Single Arm, Dose Escalation Phase 1 Trial of PRI-724 in Patients With HCV-induced Cirrhosis
Status: COMPLETED
Conditions: Hepatitis C Virus-infected Cirrhosis
Interventions: DRUG: PRI-724
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Valsalva Manœuvre in the Diagnosis of Left Ventricular Failure in Chronic Obstructive Pulmonary Disease Exacerbation
Status: COMPLETED
Conditions: Acute Heart Failure|COPD Exacerbation
Interventions: OTHER: Valsalva maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Group-based and Dual-task Focused Otago Exercises in Geriatric Individuals With Kinesiophobia
Status: COMPLETED
Conditions: Geriatric İndividual Health
Interventions: OTHER: Otago Exercise|OTHER: Dual Task Focused Otago Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Two Formulations of Propafenone 300 mg Film-coated Tablets in Healthy Adult Volunteers After a Single Oral Dose Administration Under Fasting Conditions
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Propafenone|DRUG: Rytmonorm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Low-Doses Of Isobaric Bupivacaine On Intraoperative Hemodynamics In Spinal Anesthesia During Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section|Hemodynamic Instability
Interventions: DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of Zostavax Vaccine in Patients Undergoing Living Donor Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Transplant
Interventions: BIOLOGICAL: Zostavax (Live attenuated herpes zoster vaccine)|BIOLOGICAL: Placebo vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Cytogam® on Time to Viral Load Reduction in Kidney or Kidney/Pancreas Transplant Recipients With Clinical CMV Disease
Status: COMPLETED
Conditions: Cytomegalovirus
Interventions: DRUG: CMV Immune globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of Everolimus in Preventing End-stage Renal Disease in Patients With Autosomal Dominant Polycystic Kidney Disease
Status: COMPLETED
Conditions: Autosomal Dominant Polycystic Kidney Disease
Interventions: DRUG: Placebo|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability Among Different Eutropin Formulations
Status: UNKNOWN
Conditions: Relative Bioavailability
Interventions: DRUG: Eutropin 4IU, Eutropin AQ 12IU, Eutropin Pen 36IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Repeated Subarachnoid Administrations of hUC-MSCs in Treating SCI
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: BIOLOGICAL: human umbilical cord mesenchymal stem cells (hUC-MSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: anastrozole|DRUG: everolimus|DRUG: exemestane|DRUG: goserelin acetate|DRUG: letrozole|DRUG: leuprolide acetate|DRUG: tamoxifen citrate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention Study on Molibdenum Biofortification Vegetables ( Nutri-Mo-Food )
Status: COMPLETED
Conditions: Healthy Diet
Interventions: DIETARY_SUPPLEMENT: Lettuce with no biofortification|DIETARY_SUPPLEMENT: Intervention Molibdenum group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Electro-clinical Features and Functional Connectivity Analysis in SYN1 Gene Mutation-related Epilepsy
Status: COMPLETED
Conditions: Epileptic Syndromes
Interventions: OTHER: Electro-clinical analysis of epileptic seizures|OTHER: Electro-encephalographic cases|OTHER: Clinical datas analysis|OTHER: Electro-encephalographic control
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose Adjusted vs. Fixed Dose Unilateral Laparoscopic Ovarian Drilling in PCOS Patients
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: PROCEDURE: ULOD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Cognitive Behavioral Therapy (CBT) or Sudarshan Kriya Yoga (SKY) for the Treatment of Anxiety and/or Depression in Inflammatory Bowel Disease (IBD)
Status: RECRUITING
Conditions: Crohn Disease
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Sudarshan Kriya Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pralatrexate + Romidepsin in Relapsed/Refractory Lymphoid Malignancies
Status: COMPLETED
Conditions: Lymphoid Malignancies|Multiple Myeloma|Lymphoma|Hodgkin Lymphoma|Non-hodgkin Lymphoma
Interventions: DRUG: Pralatrexate|DRUG: Romidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 19-week Cognition Study of Levetiracetam in Children With Partial Onset Seizures
Status: COMPLETED
Conditions: Epilepsy, Partial
Interventions: DRUG: Levetiracetam|OTHER: Placebo (PB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Adapted Physical Activity Program for Subjects Suffering From Haemophilia
Status: NOT_YET_RECRUITING
Conditions: Hemophilia|Sports Physical Therapy
Interventions: OTHER: AFA (Adapted Physical Activity)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: EFFICACY OF MIRROR THERAPY IN IMPROVING HAND FUNCTION POST FLEXOR TENDON REPAIR
Status: UNKNOWN
Conditions: Hand Tendon Injury
Interventions: OTHER: mirror therapy|OTHER: traditional physiotherapy protocol for flexor tendon repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors
Status: COMPLETED
Conditions: Recurrent Childhood Anaplastic Astrocytoma|Recurrent Childhood Brain Stem Glioma|Recurrent Childhood Ependymoma|Recurrent Childhood Giant Cell Glioblastoma|Recurrent Childhood Glioblastoma|Recurrent Childhood Gliosarcoma|Recurrent Childhood Medulloblastoma|Recurrent Childhood Oligodendroglioma
Interventions: DRUG: lapatinib ditosylate|PROCEDURE: therapeutic conventional surgery|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: positron emission tomography|PROCEDURE: magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avelumab With Hypofractionated Radiation Therapy in Adults With Isocitrate Dehydrogenase (IDH) Mutant Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma
Interventions: BIOLOGICAL: Avelumab|RADIATION: Hypofractionated radiation therapy (HFRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kinesiology Taping in Duchenne Muscular Dystrophy: Effects on Performance, Gait Characteristics, and Energy Consumption
Status: COMPLETED
Conditions: Performance|Energy|Gait|Duchenne Muscular Dystrophy
Interventions: DEVICE: Kinesiology Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BIOFREEDOM Stent Versus ORSIRO Stent: SORT OUT IX
Status: UNKNOWN
Conditions: Ischaemic Heart Disease
Interventions: DEVICE: Biofreedom|DEVICE: Orsiro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BIOFLOW-Dual Anti-Platelet Therapy
Status: UNKNOWN
Conditions: Percutaneous Intervention
Interventions: DEVICE: Orsiro Mission|DEVICE: Resolute Onyx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential vs. Monophasic Media Impact Trial (SuMMIT)
Status: COMPLETED
Conditions: Infertility
Interventions: OTHER: Comprehensive Chromosome Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Examine the Effect on Glucose Control and Safety/Tolerability of Exenatide Given Two Times a Day to Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: exenatide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging Synapses With [11C] UCB-J in the Human Brain
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: [11C]UCB-J radiotracer|DEVICE: PET-MR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Virtual Reality Training Versus Motor Imagery in Children With Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: Routine Physical Therapy+ Balance Training|OTHER: Virtual Reality+ Routine Physical Therapy|OTHER: Motor Imagery+ Routine Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Rotating vs. Fixed Platform of the COLUMBUS Knee Prosthesis
Status: COMPLETED
Conditions: Osteoarthritis|Rheumatoid Arthritis|Post-traumatic; Arthrosis
Interventions: DEVICE: Total Knee Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate in Patients With Severe Active Rheumatoid Arthritis, Comparing Tapering Versus Maintaining the Methotrexate Dosage
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Methotrexate (stable dose)|DRUG: Tocilizumab|DRUG: Methotrexate (tapering dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat and Isotretinoin in Treating Patients With Advanced Kidney Cancer
Status: TERMINATED
Conditions: Recurrent Renal Cell Cancer|Stage III Renal Cell Cancer|Stage IV Renal Cell Cancer
Interventions: DRUG: vorinostat|DRUG: isotretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Association of Proteinuria and Progression of Kidney Dysfunction in Sickle Cell Disease"Disease
Status: COMPLETED
Conditions: Change in Albumin to Creatinine Ratio and Glomerular Filtration Rate|Progression of Kidney Failure and or All-cause Mortality
Interventions: OTHER: no intervention study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Genetics in Predicting Risk of Bisphosphonate-Related Osteonecrosis of the Jaw in Patients With Cancer Receiving Zoledronic Acid
Status: WITHDRAWN
Conditions: Malignant Neoplasm|Musculoskeletal Complications
Interventions: DRUG: zoledronic acid|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Acute Health Effects Due to Ultrafine Particles From Candles and Cooking
Status: COMPLETED
Conditions: Candle Burning|Cooking|Lung Function Decreased|DNA Damage|Subjective Health|Asthma
Interventions: OTHER: Particles from candles|OTHER: Particles from cooking|OTHER: Clean Air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: This International Study Tests BI 690517 in Patients With Diabetic Kidney Disease. The Study Tests How 3 Different Doses of BI 690517 Are Taken up in the Body and How Well They Are Tolerated
Status: COMPLETED
Conditions: Diabetic Nephropathies
Interventions: DRUG: BI 690517|DRUG: Eplerenone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treat-to-target With Secukinumab in Axial Spondyloarthritis
Status: UNKNOWN
Conditions: Axial Spondyloarthritis|Ankylosing Spondylitis
Interventions: DRUG: Secukinumab 150 milligram [Cosentyx]
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management Of Pain After Cesarean Trial
Status: TERMINATED
Conditions: Pain, Postoperative|Opioid Use
Interventions: DRUG: Acetaminophen|DRUG: Placebo|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: e-Counseling Promotes Blood Pressure Reduction and Therapeutic Lifestyle Change in Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: e-Counseling plus Usual Care|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Somatic Acupressure for Symptom Cluster Management in Breast Cancer Patients
Status: COMPLETED
Conditions: Cancer
Interventions: OTHER: Somatic Acupressure|OTHER: Sham acupressure|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunonutrition Supplementation in Head and Neck Cancer Patients Undergoing Cancer Treatment Study
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: DIETARY_SUPPLEMENT: Immunonutrient-enriched oral nutrition supplementation|DIETARY_SUPPLEMENT: Standard medical nutrition therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Arterial Versus Venous Activated Clotting Time (ACT) Measurements During Atrial Fibrillation Ablations
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: OTHER: Venous ACT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Remineralization Effects of Hydroxyapatite Toothpaste
Status: COMPLETED
Conditions: Caries, Dental
Interventions: OTHER: Hydroxyapatite toothpaste|OTHER: Fluoridated toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improved Muscle Metabolism by Combination of Muscle Activation and Protein Substitution ( IMEMPRO )
Status: RECRUITING
Conditions: ICU Acquired Weakness|Muscle Atrophy|Energy Malnutrition Protein|Quality of Life|Morphological and Microscopic Findings|Metabolic Disturbance
Interventions: DIETARY_SUPPLEMENT: Dietary Supplement: additional substitution of protein|DEVICE: Neuromuscular electrical stimulation|OTHER: Early Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combined Effect of Continuous and Interval in Addition to Tadalafil Drug on Erectile Dysfunction
Status: UNKNOWN
Conditions: Erectile Dysfunction
Interventions: OTHER: Tadalafil 5Mg Tab + continuous and interval exercise|DRUG: Tadalafil 5Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: a-PRP Intrauterine Instillation in Women With Thin Endometrium
Status: RECRUITING
Conditions: Thin Endometrium
Interventions: PROCEDURE: PRP|OTHER: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of Roxadustat in Subjects With Different Degrees of Renal Function
Status: COMPLETED
Conditions: Normal Renal Function|Impaired Renal Function
Interventions: DRUG: Roxadustat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flavopiridol in Treating Patients With Previously Treated Chronic Lymphocytic Leukemia or Lymphocytic Lymphoma
Status: COMPLETED
Conditions: B-cell Chronic Lymphocytic Leukemia|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Waldenström Macroglobulinemia
Interventions: DRUG: alvocidib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postprandial Effects of Walnut Components Versus Whole Walnuts on Cardiovascular Disease (CVD) Risk Reduction
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Walnut "meat"|DIETARY_SUPPLEMENT: Walnut Oil|DIETARY_SUPPLEMENT: Walnut Skins|DIETARY_SUPPLEMENT: Whole walnut
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Developmental ORIgins of Healthy and Unhealthy AgeiNg: the Role of Maternal Obesity
Status: COMPLETED
Conditions: Maternal-Fetal Relations|Muscle Weakness|Insulin Resistance
Interventions: BEHAVIORAL: Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of ADGRE2 CAR-T in Patients With R/R AML
Status: NOT_YET_RECRUITING
Conditions: AML
Interventions: BIOLOGICAL: ADGRE2 CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ib Study of SUnitinib Alternating With REgorafenib in Patients With Metastatic and/or Unresectable GIST
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumor
Interventions: DRUG: Sunitinib|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy of a Cashew Apple Extract on Weight Management and Associated Metabolic Risk Factors in Overweight/Obese Volunteers
Status: UNKNOWN
Conditions: Weight Loss
Interventions: DIETARY_SUPPLEMENT: Cashew apple extract (Cashewin)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Functional MRI and DTI (Imaging Techniques) in Children With Epilepsy and Focal Brain Lesions
Status: COMPLETED
Conditions: Epilepsy
Interventions: PROCEDURE: Functional MRI, Diffusion Tensor Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Effectiveness of TARA Compared to Standard Treatment for Adolescents and Young Adults With Depression
Status: RECRUITING
Conditions: Depression in Adolescence|Depressive Disorder|Dysthymia and Chronic Depression
Interventions: BEHAVIORAL: Training for Awareness Resilience and Action (TARA)|OTHER: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iodine Supplement Strategies Between Routine Iodine Supplementation and Selective Iodine Supplementation
Status: COMPLETED
Conditions: Pregnancy Related|Iodine Deficiency
Interventions: DIETARY_SUPPLEMENT: Triferdine|DIETARY_SUPPLEMENT: Triferdine/Ferli-6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Rehabilitation for Survivors of Out-of-hospital Cardiac Arrest
Status: RECRUITING
Conditions: Cardiac Arrest|Heart Arrest|Cardiopulmonary Resuscitation|Return to Work|Return-to-work|Rehabilitation|Recovery of Function|Cardiac Rehabilitation
Interventions: OTHER: Individually tailored rehabilitation intervention|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gastrectomy Plus Prophylactic Cholecystectomy in Gastric Cancer Surgery
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: PROCEDURE: cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of an Oral Herbal Supplement on Skin Aging, Hydration, and Elasticity
Status: NOT_YET_RECRUITING
Conditions: Photoaging
Interventions: DIETARY_SUPPLEMENT: Oral herbal supplement|DIETARY_SUPPLEMENT: Oral placebo supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Synacthen Infusion on the Results of Adrenal Venous Sampling in Patient With Primary Aldosteronism
Status: UNKNOWN
Conditions: Primary Aldosteronism
Interventions: DRUG: Synacthen infusion during adrenal venous sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Antibacterial Properties of Silicon Incorporated With Quaternary Ammonium Polyethylenimine Nanoparticles
Status: UNKNOWN
Conditions: Carcinoma of Head and Neck
Interventions: DEVICE: polyethylenimine (PEI) nanoparticles.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study to Evaluate Barhemsys for the Prevention of Postoperative Nausea and Vomiting in the Bariatric Surgery Population
Status: NOT_YET_RECRUITING
Conditions: Post Operative Nausea and Vomiting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The (Cost)Effect of Smart Diaper Continence Care for People With Profound Intellectual and Multiple Disabilities
Status: UNKNOWN
Conditions: Incontinence
Interventions: DEVICE: Continence material with sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Trial With Zoledronic Acid for the Treatment of Paget's Disease of Bone, Including an Extended Observation Period
Status: COMPLETED
Conditions: Paget's Disease of Bone
Interventions: DRUG: zoledronic acid|DRUG: placebo to zoledronic acid|DRUG: Risedronate|DRUG: Placebo to risedronate|DRUG: Calcium and vitamin D supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-Articular Autologous Bone Marrow Mesenchymal Stem Cells Transplantation to Treat Mild to Moderate Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DRUG: Hyaluronic Acid|BIOLOGICAL: Autologous bone marrow-derived mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of the Dietary Approaches to Stop Hypertension(DASH) Sodium-restricted Diet in Diastolic Heart Failure
Status: COMPLETED
Conditions: Diastolic Heart Failure|Hypertensive Heart Disease
Interventions: BEHAVIORAL: DASH/sodium-restricted diet (SRD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Vedolizumab in People With Ulcerative Colitis and Crohn's Disease
Status: COMPLETED
Conditions: Ulcerative Colitis|Crohn Disease
Interventions: DRUG: Vedolizumab IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emotion Regulation Therapy for Clinical Worry and Rumination
Status: COMPLETED
Conditions: Anxiety Disorders and Symptoms|Depression, Anxiety|Generalized Anxiety Disorder|Emotional Dysfunction
Interventions: BEHAVIORAL: Emotion Regulation Therapy: 8-session version|BEHAVIORAL: Emotion Regulation Therapy: 16-session version
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of HW005 Ventricular Assist System for the Treatment of Advanced Heart Failure in Japan
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Implant of the HW005 Ventricular Assist System.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotine Pharmacokinetics and Pharmacodynamics, Safety and Tolerability of P3P
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: OTHER: P3P 1|OTHER: P3P 2|OTHER: P3P 3|OTHER: P3P 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Are the Continuous Glucose Monitoring Systems Able to Improve Long Term Glycaemic Control in Type 1 Diabetic Patients?
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Navigator®|DEVICE: Navigator®|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 3Mixtatin and MTA Vital Pulpotomy in Primary Molars
Status: NOT_YET_RECRUITING
Conditions: Pulp Disease, Dental|Deciduous Teeth
Interventions: DRUG: 3 mixtatin pulpotomy|DRUG: MTA pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of TPX-121 on Nasolabial Folds
Status: NOT_YET_RECRUITING
Conditions: Nasolabial Fold, Hypoplastic
Interventions: BIOLOGICAL: TPX-115(allogeneic fibroblasts)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adalimumab in the Treatment of Chronic Pouchitis
Status: COMPLETED
Conditions: Ulcerative Colitis|Pouchitis
Interventions: DRUG: Adalimumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LBP-EC01 in the Treatment of Acute Uncomplicated UTI Caused by Drug Resistant E. Coli (ELIMINATE Trial)
Status: RECRUITING
Conditions: Urinary Tract Infections
Interventions: DRUG: LBP-EC01 0.1 x IV dose|DRUG: LBP-EC01 0.01x IV Dose|DRUG: LBP-EC01 IV Infusion Dose|DRUG: Placebo|DRUG: LBP-EC01|DRUG: TMP/SMX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Outcome of Ortho MTA (BioMTA®) Cement vs AH Plus® Bioceramic Sealer (Dentsply).
Status: RECRUITING
Conditions: Endodontic Disease
Interventions: DEVICE: Ortho MTA cement|DEVICE: GP and AH Plus sealer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Secretin-Assisted Computed Tomography Scan and Magnetic Resonance Imaging in Improving Pancreatic Tumor Conspicuity
Status: WITHDRAWN
Conditions: Pancreas Cancer
Interventions: DRUG: Secretin Synthetic Human (RG1068)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: High Carbohydrate vs. High Fat Diets in the Treatment of Obesity (JBR 0512)
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Low calorie high carbohydrate diet|BEHAVIORAL: Low calorie high fat/protein diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-steroid Antiinflammatory Drugs to Heal Colles Fracture
Status: COMPLETED
Conditions: Colles Fracture
Interventions: DRUG: Tablets Ibumetin and placebo|DRUG: Tablets Ibumetin and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Training Effects on Cognition and Brain Function in Multiple Sclerosis: Project EXACT
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis|Cognitive Impairment
Interventions: BEHAVIORAL: Treadmill Walking Exercise Training|BEHAVIORAL: Stretching-and-Toning Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strategies to Reduce Antipsychotic-Associated Weight Gain in Youth
Status: COMPLETED
Conditions: Weight Gain
Interventions: DRUG: metformin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiochemotherapy With Panitumumab in the Localised Epidermoid Carcinoma of the Anus
Status: COMPLETED
Conditions: Epidermoid Carcinoma|Anus
Interventions: DRUG: radiochemotherapy|DRUG: Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation Of The Effectiveness And Safety Of Anidulafungin Compared To Caspofungin For The Treatment Of Deep Tissue Infection Due To Candida
Status: TERMINATED
Conditions: Candidiasis|Fungemia
Interventions: DRUG: Active anidulafungin|DRUG: Active Caspofungin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Expert Statements Concerning the Tapering of Oral Corticosteroids (OCS) for the Treatment of Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: OTHER: Brainstorming 1|OTHER: Ranking - Round 1|OTHER: Ranking - Round 2|OTHER: Ranking - Round 3
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acute Myeloid Leukemia T Cell Depletion to Improve Transplants in Adults With Acute Myeloid Leukemia (BMT CTN 0303)
Status: COMPLETED
Conditions: Leukemia, Myelocytic, Acute
Interventions: BIOLOGICAL: CD34+ selection with CliniMACS device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HORMA: Hormonal Regulators of Muscle and Metabolism in Aging
Status: COMPLETED
Conditions: Sarcopenia|Muscle Weakness|Frailty
Interventions: DRUG: Topical testosterone|DRUG: Recombinant human growth hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: BGP+ Stent as Bridging Stent in BEVAR
Status: ACTIVE_NOT_RECRUITING
Conditions: Thoracoabdominal Aortic Aneurysm, Without Mention of Rupture
Interventions: DEVICE: BGP+ Stent Graft System as bridging stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ondansetron Versus Palonosetron Antiemetic Regimen Prior to Highly Emetogenic Chemotherapy(HEC)
Status: COMPLETED
Conditions: Malignant Neoplasm
Interventions: DRUG: aprepitant|DRUG: palonosetron hydrochloride|DRUG: ondansetron|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anlotinib In Combination With RFA And TACE in Patients With Middle-advanced HCC
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Anlotinib|DEVICE: TACE+RFA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction Chemotherapy Plus Chemoradiation as First Line Treatment for Locally Advanced Cervical Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|RADIATION: Radiotherapy|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chimeric Antigen Receptor Modified T Cells Targeting BCMA for the Treatment of Relapsed/Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma|Relapsed/Refractory
Interventions: BIOLOGICAL: CAR-T treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Two Comparator, Controlled Phase 3 Study in Patients With and Without Evaporative Dry Eye
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: Omega 3|DRUG: Optive Advanced|DRUG: Optive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of TENS on Pain Threshold and Brain Activities in Healthy Adults
Status: UNKNOWN
Conditions: Transcutaneous Electrical Nerve Stimulation|Electroencephalography|Pressure Pain Threshold
Interventions: DEVICE: Acupuncture like TENS|DEVICE: Conventional TENS|DEVICE: Sham TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Application of Multi-modal Sentinel Lymph Node Staining Method in Breast Cancer Patients After Neoadjuvant Chemotherapy
Status: RECRUITING
Conditions: Sentinel Lymph Node Biopsy|Neoadjuvant Therapy|Breast Neoplasm
Interventions: DIAGNOSTIC_TEST: Identification rate of sentinel lymph node for each dual method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study of GRC 8200 in Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: GRC 8200
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of OROS Hydromorphone HCL vs Morphine in Cancer Pain Patients.
Status: COMPLETED
Conditions: Pain|Analgesics, Opioid
Interventions: DRUG: OROS hydromorphone HCL ; Morphine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Oral Rabeprazole vs. iv Omeprazole in Mild to Moderate Nonvariceal Upper Gastrointestinal Bleeding
Status: UNKNOWN
Conditions: Nonvariceal Upper Gastrointestinal Bleeding
Interventions: DRUG: Intravenous Omeprazole|DRUG: Oral Rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Inactivated and Live Attenuated Hepatitis A Vaccines
Status: COMPLETED
Conditions: Hepatitis A
Interventions: BIOLOGICAL: Attenuated Hepatitis A Vaccine, H2 Strain|BIOLOGICAL: Inactivated Hepatitis A Vaccine, Lu8 Strain|BIOLOGICAL: Group A Meningococcal Polysaccharide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Omega 3 Fatty Acids on Serum Irisin and Sirtuin-1 in Type 2 Diabetic Mellitus Patients Treated With Glimepiride
Status: COMPLETED
Conditions: Diabetic Patients
Interventions: DIETARY_SUPPLEMENT: Omega 3 fatty acids 1000 mg per day + glimepiride 2 mg or 3 mg oral|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pevonedistat and Decitabine in Treating Patients With High Risk Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Therapy-Related Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: Decitabine|OTHER: Laboratory Biomarker Analysis|DRUG: Pevonedistat|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Exposure of Simulated Hypoxia on Pulmonary Artery Pressure and Right Heart Function (Echo) Under Exercise
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DEVICE: Simulated Altitude (FiO2: 15.1%)|DEVICE: Shamed Hypoxia (FiO2: 20.9)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy Study of Two Choices of Phototherapy on Itching Skin Diseases
Status: COMPLETED
Conditions: Eczema|Psoriasis
Interventions: DEVICE: UVA / UVB phototherapy|DEVICE: UVB phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of HQK-1001 in Patients With Sickle Cell Disease
Status: TERMINATED
Conditions: Sickle Cell Disease|Sickle Cell Anemia|Sickle Cell Disorders|Hemoglobin S Disease|Sickling Disorder Due to Hemoglobin S
Interventions: DRUG: HQK-1001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Fascia Iliaca Compartment Block Versus Periarticular Infiltration
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Ropivacaine|DRUG: Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Periapical Radiography and Cone Beam Computed Tomography on Periapical Assessment Following Surgical Endodontic Treatment
Status: COMPLETED
Conditions: Periapical Diseases
Interventions: PROCEDURE: periapical surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cefiderocol Concentrations in the Lungs of Hospitalized Patients With Bacterial Pneumonia
Status: TERMINATED
Conditions: Bacterial Pneumonia
Interventions: DRUG: Cefiderocol|DRUG: Standard of Care Antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing At-risk Latina Women's Use of Genetic Counseling for Hereditary Breast and Ovarian Cancer
Status: COMPLETED
Conditions: Hereditary Breast and Ovarian Cancer
Interventions: BEHAVIORAL: Genetic Counseling and Testing YouTube Video
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING