pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Repeated Controlled Human Hookworm Infection
Status: COMPLETED
Conditions: Necator Americanus Infection
Interventions: BIOLOGICAL: 50 Necator americanus L3 larvae|BIOLOGICAL: 100 Necator americanus L3 larvae|BIOLOGICAL: 150 Necator americanus L3 larvae
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Science-Based Treatment for Opioid-Dependent Adolescents
Status: UNKNOWN
Conditions: Opioid-Dependence Among Adolescents
Interventions: DRUG: buprenorphine|DRUG: naltrexone|PROCEDURE: behavior therapy|PROCEDURE: voucher-based contingency management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Cisplatin Plus Epirubicin Salvage Chemo in Refractory Germ Cell Tumors
Status: TERMINATED
Conditions: Germ Cell Tumor
Interventions: DRUG: Cisplatin plus Epirubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ashwagandha on Salivary Antioxidant and Serum c Reactive Protein in Chronic Generalized Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Ashwagandha|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Two Behavioral Approaches to Quitting Smoking in Mental Health Settings
Status: RECRUITING
Conditions: Tobacco Use Disorder|Mental Illness|Recurring Major Depressive Disorder|Bipolar Disorder|Schizophrenia|Schizoaffective Disorder|Persistent Depressive Disorder
Interventions: DEVICE: Quit on the Go App (formerly "Learn to Quit " App)|BEHAVIORAL: Brief advice|DRUG: Nicotine patch|BEHAVIORAL: Smartphone coaching|DRUG: Nicotine gum|DRUG: Nicotine Lozenges
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vactosertib With Nal-IRI/FL in Metastatic Pancreatic Ductal Adenocarcinoma.
Status: UNKNOWN
Conditions: Pancreas Cancer
Interventions: DRUG: Vactosertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Thymoquinone in Psoriasis Vulgaris
Status: NOT_YET_RECRUITING
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Topical thymoquinone Ointment|DRUG: topical placebo ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study Evaluating Efficacy, Safety and Pharmacokinetics of Pasireotide in Patients With Dumping Syndrome
Status: COMPLETED
Conditions: Dumping Syndrome
Interventions: DRUG: SOM230
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Oxaliplatin, Capecitabine, and Bevacizumab to Treat Older Patients With Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer|Neoplasm Metastasis
Interventions: DRUG: oxaliplatin, capecitabine, bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HDV-Interferon in the Treatment of Chronic Hepatitis C Nonresponders and Naive Hepatitis C Patients
Status: UNKNOWN
Conditions: Chronic Hepatitis C
Interventions: DRUG: Oral HDV-Interferon + ribavarin|DRUG: Injectable HDV-Interferon + ribavarin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ANTIBODY-LEVEL BASED ANALYSIS OF COVID-19 CONVALESCENT SERUM (ABACCuS)
Status: TERMINATED
Conditions: COVID-19|Severe Acute Respiratory Syndrome (SARS)|Coronavirus Infections
Interventions: BIOLOGICAL: COVID-19 convalescent plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics in Infants With Cyanotic Congenital Heart Disease
Status: COMPLETED
Conditions: Cyanotic Congenital Heart Disease
Interventions: DIETARY_SUPPLEMENT: Bifidobacterium infantis|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Interdisciplinary Interventions to Address Pain Management Among Head and Neck Cancer Patients
Status: RECRUITING
Conditions: Head and Neck Carcinoma
Interventions: OTHER: Best Practice|OTHER: Counseling|PROCEDURE: Electroencephalography|BEHAVIORAL: Neurofeedback|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long-Term Safety of Latanoprostene Bunod Ophthalmic Solution 0.024% in Japanese Subjects With OAG or OHT
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: Latanoprostene bunod
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Hormonal Therapy Combined With Chemoimmunotherapy
Status: TERMINATED
Conditions: HER2-positive Breast Cancer|ER-positive Breast Cancer
Interventions: DRUG: fulvestrant 500 mg|DRUG: Docetaxel|DRUG: Trastuzumab (H, 8mg/kg|DRUG: Pertuzumab (P, 840 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-ranging Study to Evaluate Efficacy and Safety of VX-150 in Subjects With Acute Pain Following Bunionectomy
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: VX-150|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Lower Leg Heating and Transcutaneous Electrical Nerve Stimulation on Exercise Capacity in Patients With PAD
Status: UNKNOWN
Conditions: Peripheral Arterial Disease
Interventions: BEHAVIORAL: Lower leg heating|BEHAVIORAL: Lower leg transcutaneous electrical nerve stimulation (TENS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gastric and Intestinal Satiation in Obese and Normal Weight Healthy People
Status: COMPLETED
Conditions: Endocrine System Diseases
Interventions: DIETARY_SUPPLEMENT: ensure plus|DIETARY_SUPPLEMENT: standardized test meal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Portable Continuous Positive Airways Pressure (CPAP) in Excessive Central Airway Collapse (ECAC) Study
Status: RECRUITING
Conditions: Excessive Central Airways Collapse|Respiratory Disease|Tracheobronchomalacia|Excessive Dynamic Airway Collapse
Interventions: DEVICE: Use of portable CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment With Pazopanib for Neoadjuvant Breast Cancer
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: doxorubicin + cyclophosphamide|DRUG: paclitaxel + pazopanib|PROCEDURE: surgery|DRUG: pazopanib monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Progesterone Suppression of Nocturnal LH Increases in Pubertal Girls
Status: COMPLETED
Conditions: Female Puberty
Interventions: DRUG: Progesterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: INSORB Versus Subcuticular Sutures at Cesarean Section
Status: TERMINATED
Conditions: Cesarean Section|Pregnancy
Interventions: COMBINATION_PRODUCT: Insorb absorbable staples|COMBINATION_PRODUCT: Absorbable sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lixisenatide for Restoration of Insulin Release in Subjects With Diabetes Mellitus Type 2
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Lixisenatide (AVE0010)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BCMA Chimeric Antigen Receptor Expressing T Cells Therapy for Relapsed/Refractory Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: Anti-BCMA CAR-T cells|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Immune inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Histological Study to Assess Safety and Efficacy of the TempSure Firm for Non-Invasive Lipolysis
Status: COMPLETED
Conditions: Non-invasive Lipolysis
Interventions: DEVICE: TempSure Firm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Contrast Enhanced Spectral Mammography to Predict Upgrade Rates of Biopsy Proven Atypical Ductal Hyperplasia
Status: TERMINATED
Conditions: Atypical Ductal Hyperplasia
Interventions: DEVICE: Contrast enhanced mammography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of PACK Health Support Program on Patient Reported Outcomes in Patients With Breast Cancer
Status: COMPLETED
Conditions: Breast Carcinoma|Breast Ductal Carcinoma In Situ|Invasive Breast Carcinoma|Recurrent Breast Carcinoma
Interventions: OTHER: Best Practice|OTHER: Medical Chart Review|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|PROCEDURE: Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vigorous Cool Room Treadmill Training
Status: COMPLETED
Conditions: Multiple Sclerosis|Rehabilitation|Gait Disorders, Neurologic|Neuronal Plasticity
Interventions: OTHER: Body-weight supported treadmill training in a room cooled to 16°C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Disulfiram and Metformin in Glioblastomas
Status: TERMINATED
Conditions: Glioblastoma
Interventions: DRUG: Disulfiram|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Aerobic Fitness or Muscle Mass Training to Improve Colorectal Cancer Outcome
Status: RECRUITING
Conditions: Colorectal Cancer|Chemotherapeutic Toxicity|Survivorship|Lifestyle
Interventions: BEHAVIORAL: Continuous aerobic and resistance exercise intervention|BEHAVIORAL: Continuous aerobic and aerobic interval exercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment for Post Acute COVID-19 Syndrome
Status: UNKNOWN
Conditions: Tinnitus, Subjective
Interventions: DRUG: Pimozide 1 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of 2141-V11 in People With Non-muscle Invasive Bladder Cancer That Did Not Respond to Standard Treatment
Status: RECRUITING
Conditions: Non-muscle Invasive Bladder Cancer
Interventions: DRUG: anti-CD40 antibody 2141-V11|DRUG: anti-CD40 antibody 2141-V11|DRUG: anti-CD40 antibody 2141-V11
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Non Significant Risk, Adhesive Wear Validation Study for the On Body Drug Delivery Device Component of the SQIN-01 Furosemide Infusor (Infusor Device)
Status: COMPLETED
Conditions: Healthy Volunteer Study
Interventions: OTHER: 3M 1529 Adhesive Tape
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Tilpisertib Fosmecarbil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: How Does Pianistic Musical Training Influence the Development of Alzheimer's Disease?
Status: NOT_YET_RECRUITING
Conditions: Dementia of Alzheimer Type|Dementia|Dementia, Vascular|Dementia, Mixed|Dementia Frontal|Dementia With Lewy Bodies|Cognitive Decline|Neurologic Disorder|Neurologic Dysfunction|Neurologic Deficits
Interventions: BEHAVIORAL: Music therapy based on piano learning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Drying Before Plastic Wrapping on Thermal Losses in Very Preterm Infants at Birth
Status: NOT_YET_RECRUITING
Conditions: Temperature Regulation; Disorder, Fetus or Newborn
Interventions: OTHER: Drying before wrapping|OTHER: No drying before wrapping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ra-223 in PSMA PET Optimally Selected Patients
Status: NOT_YET_RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Malignant Neoplasm in the Bone|Stage IVB Prostate Cancer AJCC v8
Interventions: DRUG: Radium-223|PROCEDURE: PSMA Positron Emission Tomography (PET) Scan|DRUG: Technetium Tc 99M Medronate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Plus Epacadostat, Pembrolizumab Monotherapy, and the EXTREME Regimen in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (KEYNOTE-669/ECHO-304)
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Epacadostat|DRUG: Cetuximab|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liner Ablation Using Contact-force in Atrial Fibrillation
Status: UNKNOWN
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: Pulmonary vein isolation|PROCEDURE: Contact force assisted left atrial linear ablation|PROCEDURE: left atrial linear ablation without contact force monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Screening for Cervical Cancer Among Women Living With HIV in the Dominican Republic
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Female Reproductive System Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Interview
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Multivessel TALENT
Status: RECRUITING
Conditions: Coronary Artery Disease|Myocardial Ischemia|Coronary Disease|Heart Diseases|Cardiovascular Diseases|Arterial Occlusive Diseases|Vascular Diseases
Interventions: DEVICE: SUPRAFLEX Cruz|DEVICE: SYNERGY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Immunogenicity of rVSVΔG-SEBOV-GP Vaccine in Adults With Good General Health
Status: ACTIVE_NOT_RECRUITING
Conditions: Ebola Sudan Virus Disease
Interventions: DRUG: rVSV∆G-SEBOV-GP Vaccine or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of SilOss® in Periodontal Surgery
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: BIOLOGICAL: Siloss® bone graft|BIOLOGICAL: Hydroxyapatitie Bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab Plus SurVaxM for Glioblastoma at First Recurrence
Status: COMPLETED
Conditions: Recurrent Glioblastoma
Interventions: DRUG: Pembrolizumab|DRUG: SurVaxM|DRUG: Sargramostim|DRUG: Montanide ISA 51
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Metformin Extended Release Compared With Mono Compound Tablets in Healthy Male and Female
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: metformin|DRUG: empagliflozin/metformin|DRUG: empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DEBlue Stent vs Cypher Stent in the Treatment of Advanced Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: DEBlue stent vs. Cypher stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Omnyx™ Integrated Digital Pathology System in the Primary Diagnosis of Surgical Pathology Specimens
Status: UNKNOWN
Conditions: Primary Diagnosis of Surgical Pathology Specimens
Interventions: OTHER: Omnyx™ IDP system|OTHER: Conventional light microscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate Efficacy and Safety of Abatacept in Participants of Pemphigus Vulgaris (PV)
Status: UNKNOWN
Conditions: Pemphigus Vulgaris
Interventions: DRUG: Abatacept Prefilled Syringe|DRUG: Mycophenolate Mofetil 500Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Estimating The Optimal Radiation Volume Of Postsurgical Radiation For Patients With Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: RADIATION: enlarge irradiation volume|RADIATION: Small volume radiation|DRUG: cisplatin|DRUG: fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double-balloon Colonoscopy to Increase Colonoscopy Completion Rate
Status: TERMINATED
Conditions: Colorectal Cancer|Colorectal Adenomas|Inflammatory Bowel Disease
Interventions: PROCEDURE: Fujinon EC-450BI5 double-balloon colonoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study on the Effects of Intravenous Dexmedetomidine on Pain in Patients Undergoing Elective Spinal Surgery
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: Dexmedetomidine|OTHER: Placebo Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plasma DNA and Vascular Remodelling in Patients With Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: PROCEDURE: micro- and macro-circulatory vascular remodelling measures not practice in routine care|PROCEDURE: Biological measures not practice in routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: High-dose Inhalations of Nitric Oxide in the Treatment of Pneumonia
Status: RECRUITING
Conditions: Nosocomial Pneumonia|Community-acquired Pneumonia
Interventions: DRUG: 200 ppm Nitric Oxide|DRUG: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conservative Management of Morbidly Adherent Anterior Situated Placenta
Status: COMPLETED
Conditions: Placenta Accreta
Interventions: PROCEDURE: Cervico- isthmic compression suture|PROCEDURE: Anterior wall uterine resection:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Transfusion Related Acute Gut Injury (TRAGI) in Extremely Low Gestational Age Neonates (ELGANs) Using iNO
Status: UNKNOWN
Conditions: Anemia
Interventions: DRUG: Inhaled Nitric Oxide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men and Women to Test if Taking Different Formulations of BI 730357 Tablets Influences the Amount of BI 730357 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 730357 (Test)|DRUG: BI 730357 (Reference)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid Use After Urogynecologic Procedures: Using a Predictive Calculator
Status: COMPLETED
Conditions: Post Operative Pain|Opioid Use|Prolapse Genital
Interventions: OTHER: Opioid calculator|OTHER: Standard opioid prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Valsartan/Hydrochlorothiazide Combination Therapy in Patients With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Valsartan/Hydrochlorothiazide|DRUG: HCTZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Efficacy and Safety of Venetoclax Combined With HAA Regimen in Newly Diagnosed Young AML.
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Venetoclax
Interventions: COMBINATION_PRODUCT: combination of venetoclax and HAA regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Iyengar Yoga Practice on Patients With Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis, Iyenagar Yoga, Yoga, EDSS
Interventions: OTHER: The effect of Iyengar yoga practice on patients with multiple sclerosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Sensitivity in NREM Parasomnia (NOCISOMNIE)
Status: WITHDRAWN
Conditions: NREM Parasomnia|Sleepwalking|Sleep Terror
Interventions: OTHER: Case Intervention|OTHER: Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: ExAblate Transcranial MR Guided Focused Ultrasound for the Treatment of Essential Tremors
Status: COMPLETED
Conditions: Essential Tremor
Interventions: DEVICE: Transcranial ExAblate|DEVICE: Sham Transcranial ExAblate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Monovalent Oral Poliovirus Vaccine Type 1 Intestinal and Humoral Immunity Study
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: mOPV1|BIOLOGICAL: bOPV|BIOLOGICAL: fIPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2849466 in Healthy Male Subjects
Status: COMPLETED
Conditions: Cachexia
Interventions: DRUG: GSK2849466|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Phase Ib/II Study of BY101298 , an Oral DNA-PK Inhibitor, Combined With Radiotherapy in Patients With Malignant Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor, Adult
Interventions: DRUG: BY101298 Capsules|RADIATION: palliative radiotherapy|DRUG: BY101298 Capsules|RADIATION: curative radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Stablor on Visceral Fat Loss in Patients With a Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Stablor|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect and Safety of Local Injection of Botulinum Toxin Type B Against Digital Ulcer in Systemic Sclerosis
Status: COMPLETED
Conditions: Systemic Sclerosis Patients With Digital Ulcers
Interventions: DRUG: Botulinum toxin type B (2500 units / vial)|DRUG: Physiological saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: This is a 6-month Observational Study. Patients Included Will be Those Referred With a Possible Diagnosis or an Established Diagnosis of Asthma. It Will Look at the Association of the Asthma Microbiome and Disease Characteristics, Severity and Treatment Response.
Status: NOT_YET_RECRUITING
Conditions: Asthma
Interventions: DRUG: Biologic Agent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial to Evaluate the Safety and Efficacy of ADX-629 in in Subjects With Elevated Ethanol Levels
Status: COMPLETED
Conditions: Ethanol Intoxication
Interventions: DRUG: ADX-629|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Effects of Testosterone Replacement Therapy in Aging Men With Androgen Deficiency
Status: COMPLETED
Conditions: Men With Low Testosterone Levels
Interventions: DRUG: Testosterone Enanthate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of exoASO-STAT6 (CDK-004) in Patients With Advanced Hepatocellular Carcinoma (HCC) and Patients With Liver Metastases From EIther Primary Gastric Cancer or Colorectal Cancer (CRC)
Status: TERMINATED
Conditions: Advanced Hepatocellular Carcinoma (HCC)|Gastric Cancer Metastatic to Liver|Colorectal Cancer Metastatic to Liver
Interventions: DRUG: CDK-004
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heading Off Peripheral Neuropathy With Exercise
Status: TERMINATED
Conditions: Peripheral Nervous System Disorders|Breast Neoplasms|Chemotherapy
Interventions: BEHAVIORAL: Aerobic/ Resistance Exercise Intervention|BEHAVIORAL: Attention control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PVP Iodine vs Chlorhexidine in Alcohol for Disinfection of the Surgical Site
Status: COMPLETED
Conditions: Surgical Site Infections
Interventions: DRUG: CHX disinfection|DRUG: PI Disinfection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Analgesic Efficacy of Anterior Femoral, Genicular and Adductor Canal Nerve Block
Status: RECRUITING
Conditions: Pain, Postoperative
Interventions: OTHER: ACB|OTHER: ACB + iPACK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Administering Multiple Oral Doses of GSK1292263 Alone and With Atorvastatin
Status: COMPLETED
Conditions: Dyslipidaemias|Dyslipidemias
Interventions: DRUG: 10mg atorvastatin|DRUG: 80mg atorvastatin|DRUG: GSK1292263 Placebo|DRUG: 100mg GSK1292263|DRUG: 300mg GSK1292263|DRUG: 800mg GSK1292263|DRUG: 10mg ezetimibe|OTHER: Washout
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Physical and Metabolic Abnormalities in HIV Infected and Uninfected Children and Youth
Status: COMPLETED
Conditions: HIV Infections|HIV-Associated Lipodystrophy Syndrome|HIV Lipodystrophy Syndrome|Lipodystrophy|Dyslipidemia|Osteoporosis|Osteopenia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Sleep2BWell Cluster-Randomized Trial
Status: NOT_YET_RECRUITING
Conditions: Blood Pressure|Sleep Health|Diet, Healthy|Physical Activity|Weight Loss
Interventions: BEHAVIORAL: Multidimensional Sleep Health Sessions|BEHAVIORAL: Healthy Diet Sessions|BEHAVIORAL: Physical Activity Sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Renal Impaired Subjects and Healthy Subjects
Status: COMPLETED
Conditions: Solid Tumours
Interventions: DRUG: selumetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Evaluating the Pharmacokinetics of the Potential Drug Interaction Between CYP2C9 Inhibitor and Substrate
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: pharmacokinetic (how the body absorbs and eliminates) interaction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Immunotherapy With Toripalimab Following Curative-intent Ablation for Recurrent Hepatocarcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Toripalimab|PROCEDURE: Thermal ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cornell University-Micronutrient Initiative Calcium Supplementation Study
Status: COMPLETED
Conditions: Preeclampsia
Interventions: DIETARY_SUPPLEMENT: Regimen A calcium and iron/folic acid|DIETARY_SUPPLEMENT: Regimen B calcium and iron/folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Cutera Excel V™ Laser With Green Genesis and Micro-Lens Array (MLA)Attachment
Status: COMPLETED
Conditions: Wrinkle|Rosacea|Scarring
Interventions: DEVICE: Excel V™ Laser With Green Genesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Non-inferiority Study of Unresectable Hepatocelluar Carcinoma Receiving Stereotactic Radiotherapy Combined With Hepatic Arterial Chemoembolization Compared With Conversion Hepatectomy
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma Non-resectable|Conversion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Validation of VI-RADS for the Detection of Detrusor Muscle Invasion
Status: UNKNOWN
Conditions: Bladder Cancer
Interventions: DIAGNOSTIC_TEST: multi parametric MRI|PROCEDURE: transurethral resection of bladder tumor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Oslo Study of Clonidine in Elderly Patients With Delirium
Status: TERMINATED
Conditions: Delirium
Interventions: DRUG: Clonidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Preliminary Efficacy of Atezolizumab (Anti-Programmed Death-Ligand 1 [PD-L1] Antibody) in Pediatric and Young Adult Participants With Solid Tumors
Status: TERMINATED
Conditions: Solid Tumor
Interventions: DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Acoustic Stimulation During Sleep Boost Slow Wave Sleep and Memory Performance?
Status: COMPLETED
Conditions: Healthy|Mild Cognitive Impairment|Alzheimer Disease
Interventions: OTHER: Closed loop acoustic stimulation|OTHER: Sham acoustic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ph Ib/IIa Study of Cabazitaxel Plus Bavituximab in Castration-resistant Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer|Prostatic Neoplasms
Interventions: DRUG: Cabazitaxel plus bavituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanisms Behind Severe Insulin Resistance During Pregnancy in Women With Glucose Metabolic Disorders (SIR-MET)
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Gestational Diabetes|Overweight and Obesity|Pregnancy in Diabetic|Insulin Resistance|Insulin Sensitivity|Pregnancy, High Risk
Interventions: OTHER: No interventions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analysis of Gut Microbiota in Patients With Brain Metastasis of Non-small Cell Lung Cancer Treated by Pembrolizumab Combined With Chemotherapy
Status: UNKNOWN
Conditions: Gut Microbiota|NSCLC|Pembrolizumab|Chemotherapy
Interventions: DRUG: Pembrolizumab Combined With Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Dose Study of LY2189265 in Subjects With Varying Degrees of Hepatic (Liver) Impairment
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY2189265
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EFFECT - EFFectiveness of ESPB (Erector Spinae Plane Block) in Laparoscopic Cοlectomies Trial
Status: UNKNOWN
Conditions: Pain, Postoperative|Acute Pain|Postoperative Complications|Pain|Ropivacaine|Analgesia|Regional Anesthesia|Analgesics|Anesthesia, Local|Colorectal Cancer|Perioperative Pain
Interventions: DRUG: Ropivacaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Effect of Rosuvastatin on Cisplatin-induced Nephrotoxicity and Ototoxicity
Status: UNKNOWN
Conditions: Cisplatin Adverse Reaction
Interventions: DRUG: Rosuvastatin 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Gastrointestinal Microbiome of Infants With GERD and PPI Therapy: a Pilot Study
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: PPI therapy|PROCEDURE: Stool sample|PROCEDURE: Stool sample|PROCEDURE: Stool sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Meta-analysis Comparing Toothbrushes on Plaque Removal and Gingival Health
Status: COMPLETED
Conditions: Gingivitis|Dental Plaque
Interventions: DEVICE: Oscillating-rotating electric toothbrush|DEVICE: Sonic electric toothbrush|DEVICE: Manual toothbrush
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Bioavailability Study of Two Test Products of Fixed Dose Combination Capsule of ASA (Acetylsalicylic Acid) and Pantoprazole (Each Capsule Contains ASA 100 mg and Pantoprazole 20 mg) Under Fasting Conditions
Status: COMPLETED
Conditions: Ulcers, Duodenal and Gastric
Interventions: DRUG: Test 1= ASA 100 mg and pantoprazole 20 mg capsule formulation one|DRUG: Test 2= ASA 100 mg and pantoprazole 20 mg capsule formulation two|DRUG: ASA 100 mg tablet|DRUG: Pantoprazole 20 mg gastro-resistant tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systematic Oral Nutritional Support in Hospitalized, Moderately Hypophagic Patients at Nutritional Risk
Status: UNKNOWN
Conditions: Nutritional Support
Interventions: DIETARY_SUPPLEMENT: Intensive nutritional counseling|OTHER: Dietary counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-in-Human PoC Study With BEN2293 in Patients With Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: BEN2293 (0.25% or 1.0% w/w) or matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Reactogenicity of GSK Biologicals' Inactivated Poliomyelitis Vaccine (IPV) (Poliorix) in Infants
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: Poliorix
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Valsartan Intensified Primary Care Reduction of Blood Pressure Study
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Valsartan and hydrochlorothiazide (HCTZ) - monotherapy|DRUG: Valsartan and amlodipine|DRUG: Usual care|DRUG: Valsartan|DRUG: Valsartan and hydrochlorothiazide (HCTZ) - combination arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Independent Housing and Support for People With Severe Mental Illness
Status: COMPLETED
Conditions: Severe Mental Disorder
Interventions: BEHAVIORAL: Independent Housing and Support (IHS)|BEHAVIORAL: Residential Care Settings and other Treatment as Usual (RCS/TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed/Refractory Hematologic Malignancies
Status: RECRUITING
Conditions: T Cell Lymphoma|B Cell Lymphoma|Acute Myeloid Leukemia
Interventions: BIOLOGICAL: CTX131
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Computer-based Cognitive Training for Executive Functions After Stroke
Status: UNKNOWN
Conditions: Stroke|Executive Dysfunction|Cognitive Impairment|Randomized Controlled Trial
Interventions: OTHER: CogniPlus|OTHER: Training As Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ZN-c3 and Niraparib in Subjects With Platinum-Resistant Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer|Platinum-resistant Ovarian Cancer|Primary Peritoneal Carcinoma|Fallopian Tube Cancer
Interventions: DRUG: ZN-c3|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacies of Hybrid and High-dose Dual Therapies for the First-line Anti-H Pylori Treatment
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Pariet|DRUG: Amolin|DRUG: Klaricid|DRUG: Flagyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: Paxalisib|DRUG: Metformin|OTHER: Ketogenic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study To Evaluate The Pharmacokinetics And Safety Of Three Modified Release And One Immediate Release Formulations Of Tofacitinib (CP-690,550) In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: tofacitinib (CP-690,550) modified-release formulation A|DRUG: tofacitinib (CP-690,550) modified-release formulation B1|DRUG: tofacitinib (CP-690,550) modified-release formulation A|DRUG: tofacitinib (CP-690,550) modified-release formulation B1|DRUG: tofacitinib (CP-690,550) modified-release formulation B2|DRUG: tofacitinib (CP-690,550) immediate-release formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: AFFECT Study for Patients With Intraventricular Hemorrhage, Subarachnoid Hemorrhage, Subdural Hematoma, and Ventriculitis
Status: RECRUITING
Conditions: Intraventricular Hemorrhage|Subarachnoid Hemorrhage|Subdural Hematoma|Ventriculitis
Interventions: DEVICE: IRRAflow with Active Fluid Exchange System|DEVICE: External Ventricular Drain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Iron Content of Ferritin in Serum and Urine of Children With High Serum Ferritin Levels
Status: TERMINATED
Conditions: Iron Overload
Interventions: DIAGNOSTIC_TEST: Serum Ferritin level|DIAGNOSTIC_TEST: Serum Ferritin iron content|DIAGNOSTIC_TEST: Urine Ferritin level|DIAGNOSTIC_TEST: Urine ferritin iron content
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Carotid Revascularization Versus Best Medical Treatment for Asymptomatic Carotid Stenosis
Status: RECRUITING
Conditions: Carotid Artery Stenting|Carotid Endarterectomy|Best Medical Treatment|Carotid Artery Stenosis Asymptomatic
Interventions: PROCEDURE: Carotid Revascularization|DRUG: Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Sodium Bicarbonate Supplementation in Athletes
Status: ACTIVE_NOT_RECRUITING
Conditions: Supplementation|Sport
Interventions: DIETARY_SUPPLEMENT: Sodium bicarbonate supplementation|DIETARY_SUPPLEMENT: Placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gastrointestinal Tolerance of Under-five Children With Severe Acute Malnutrition to ONS Compared to F-75/F-100
Status: COMPLETED
Conditions: Severe Acute Malnutrition
Interventions: OTHER: High Energy Oral Nutrition Supplement|OTHER: Standard Energy Oral Nutrition Supplement|OTHER: Formula-75/Formula-100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Microbiome-changing Interventions on Food Decision-making
Status: RECRUITING
Conditions: Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Inulin|BEHAVIORAL: Lifestyle intervention|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy Study of ABT-089 in Adults With Mild to Moderate Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: ABT-089|DRUG: ABT-089|DRUG: ABT-089|DRUG: ABT-089|DRUG: ABT-089|DRUG: ABT-089|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Cranberries in Women With Preterm Premature Rupture of Membranes
Status: UNKNOWN
Conditions: Fetal Membranes, Premature Rupture|Premature Birth
Interventions: DRUG: Cranberries - Vaccinium macrocarpon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Emotion Recognition Modification for Bipolar Disorder
Status: WITHDRAWN
Conditions: Bipolar Disorder
Interventions: OTHER: emotion recognition modification - sad>happy|OTHER: emotion recognition modification - sad>happy control|OTHER: emotion recognition modification - angry>happy|OTHER: emotion recognition modification - angry>happy control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Olverembatinib for FGFR1-rearranged Neoplasms
Status: RECRUITING
Conditions: Myeloproliferative Neoplasm|Acute Leukemia
Interventions: DRUG: Olverembatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Noninvasive Targeted Pulsed Electromagnetic Field (tPEMF) on Opioid Use, Pain, and Joint Function Following Total Knee Arthroplasty
Status: TERMINATED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Ivivi Torino II|DEVICE: Ivivi Torino II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT