pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparative Effect of Scapular Stabilization vs Thoracic Extension Exercises in Young Adults With Text Neck Syndrome.
Status: RECRUITING
Conditions: Neck Syndrome|Forward Head Posture
Interventions: OTHER: Scapular stabilization exercises|OTHER: Thoracic extension exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin Efficacy and Action in NASH
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Study to Compare Efficacy, Safety and Tolerability of Hydroxychloroquine Combined With Azithromycin Compared to Hydroxychloroquine Combined With Camostat Mesylate and to "no Treatment" in SARS CoV 2 Virus
Status: UNKNOWN
Conditions: COVID - 19
Interventions: DRUG: hydroxychloroquine in combination with camostat mesylate|DRUG: Hydroxychloroquine in combination of Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-inferiority Trial of Two Snake Antivenoms in CAR (PAVES)
Status: WITHDRAWN
Conditions: Snake Bites
Interventions: BIOLOGICAL: FAV-Africa|BIOLOGICAL: EchiTabPlus-ICP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Positive Airway Pressure to Improve Milder Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Lung Diseases|Sleep Apnea Syndromes|Hypertension
Interventions: DEVICE: Continuous Positive Airway Pressure (CPAP) Treatment|DEVICE: Sham CPAP device - CPAP device with pressure delivered <1 cm H20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy of Paclitaxel and Carboplatin With or Without Anthracycline as Aneo Adjuvant Treatment in Advanced Endometrial Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Endometrial Carcinoma
Interventions: DRUG: Paclitaxel/epirubcin/carboplatin|DRUG: Paclitaxel/carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate the Efficacy, Safety and Tolerability of E2027 (Hereinafter Referred to as Irsenontrine) in Participants With Dementia With Lewy Bodies
Status: COMPLETED
Conditions: Dementia With Lewy Bodies
Interventions: DRUG: Irsenontrine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase IIb Study to Evaluate a Long-Acting Intramuscular Regimen for Maintenance of Virologic Suppression (Following Induction With an Oral Regimen of GSK1265744 and Abacavir/Lamivudine) in Human Immunodeficiency Virus Type 1 (HIV-1) Infected, Antiretroviral Therapy-Naive Adult Subjects
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus|HIV Infections
Interventions: DRUG: CAB Oral Tablets|DRUG: CAB LA|DRUG: ABC/3TC Oral tablets|DRUG: RPV Oral Tablets|OTHER: HAART|DRUG: RPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Agitated Saline, Albumin, or Propofol-albumin Mixture for Enhanced Contrast in TEE Examinations
Status: COMPLETED
Conditions: Transesophageal Echocardiography Contrast Agents
Interventions: DRUG: normal saline|DRUG: human albumin|DRUG: human albumin and propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Family-Based Behavioral Medical Nutrition Therapy Education in Children and Adolescents With Type 1 Diabetes
Status: COMPLETED
Conditions: Type1diabetes
Interventions: OTHER: Medical nutrition therapy and carbohydrate counting education|OTHER: Medical nutrition therapy and carbohydrate counting education|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Pilot Trial of Alpha Lipoic Acid (ALA) for Weight Loss in Schizophrenia
Status: COMPLETED
Conditions: Obesity|Weight Loss|Schizophrenia
Interventions: DIETARY_SUPPLEMENT: Alpha Lipoic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 28-Day Repeated Topical Study to Evaluate the Safety and Activity of 5 Escalating Dose Levels of SAR366234 and One Dose of Latanoprost in Patients With Open Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open Angle Glaucoma -Ocular Hypertension
Interventions: DRUG: Latanoprost|DRUG: SAR366234
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sitagliptin Prophylaxis for Glucocorticoid-Induced Impairment of Glucose Metabolism in Males With the Metabolic Syndrome
Status: COMPLETED
Conditions: Diabetes Mellitus|Steroid Diabetes|Glucocorticoid-induced Diabetes|Beta-cell Function
Interventions: DRUG: Sitagliptin 100 mg|DRUG: Prednisolone 30 mg|DRUG: Sitagliptin-placebo|DRUG: Prednisolone-placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Membrane Phospholipid and Energy Metabolism in Subjects at High Risk of Psychotic Transition
Status: RECRUITING
Conditions: Patients With Ultra High Risk of Psychotic Transition
Interventions: DIAGNOSTIC_TEST: Cerebral MRI with Phosphorus 31 Magnetic Resonance Spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison in Efficacy and Safety Between Interferon Alfacon-1 Alone and Concomitant Dosing With Ribavirin for the Treatment of Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Interferon alfacon-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Ventilator Safety in Patients on Pressure-Support Ventilation
Status: COMPLETED
Conditions: Acute Respiratory Failure|Mechanical Ventilation Complication|Ventilator-Induced Lung Injury
Interventions: DEVICE: Viasys Avea Ventilator|DEVICE: Philips Respironics NM3 device|DEVICE: Servo U ventilator|DEVICE: Vyaire SmartCath adult nasogastric tube with Esophageal balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Switching Therapy From Lamivudine to Telbivudine Versus Continued Lamivudine in Adults With Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Lamivudine|DRUG: Telbivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Outcome of Moderate Severity in OPC Poisoning Patients When Treated With Pralidoxime
Status: RECRUITING
Conditions: Organophosphorus Poisoning
Interventions: DRUG: Pralidoxime|DRUG: Atropine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of MRG-106 in Patients With Mycosis Fungoides (MF), CLL, DLBCL or ATLL
Status: COMPLETED
Conditions: Cutaneous T-cell Lymphoma (CTCL)|Mycosis Fungoides (MF)|Chronic Lymphocytic Leukemia (CLL)|Diffuse Large B-Cell Lymphoma (DLBCL), ABC Subtype|Adult T-Cell Leukemia/Lymphoma (ATLL)
Interventions: DRUG: Cobomarsen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intramuscular Injection of Mesenchymal Stem Cell for Treatment of Children With Idiopathic Dilated Cardiomyopathy
Status: UNKNOWN
Conditions: Dilated Cardiomyopathy
Interventions: BIOLOGICAL: umbilical cord mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Great Auricular Nerve Block for Children Undergoing Tympanomastoid Surgery
Status: COMPLETED
Conditions: Tympanomastoid Surgery|Cochlear Implant|Mastoidectomy|Cholesteatoma
Interventions: DRUG: 0.25% Bupivacaine + Clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Glycemic Control Achieved With 2 Different Needles
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Delivery Systems
Interventions: DEVICE: NovoFine® needle 6 mm|DEVICE: Ultra-Fine needle 12.7 mm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of MDX-1401 in Patients With CD30-positive Refractory/Relapsed Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Hodgkin's Lymphomas
Interventions: BIOLOGICAL: MDX-1401
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Lung Avoidance for Individualized Radiotherapy (FLAIR): A Randomized, Double-Blind Clinical Trial
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Concurrent platinum-based chemotherapy|RADIATION: Standard Radiotherapy, 60 Gy in 30 fractions.|RADIATION: Functional Lung Avoidance Radiotherapy, 60 Gy in 30 fractions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: VISN Collaborative for Improving Hypertension Management With ATHENA-HTN
Status: COMPLETED
Conditions: Hypertension
Interventions: OTHER: ATHENA-CDS-HTN plus Guideline Link|OTHER: Guideline Link Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Biomimetic Stent and Vascular Functions Study
Status: RECRUITING
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Bio-MIMICS 3D Stent|DEVICE: Innova Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ABT-751 in Treating Children With Neuroblastoma That Has Relapsed or Not Responded to Previous Treatment
Status: COMPLETED
Conditions: Disseminated Neuroblastoma|Recurrent Neuroblastoma
Interventions: DRUG: ABT-751|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Size of the Gastric Remnant as Determinant for Delayed Gastric Emptying After Whipple Resection.
Status: TERMINATED
Conditions: 50 % Reduction of Delayed Gastric Emptying
Interventions: PROCEDURE: Subtotal gastrectomy as an adjunct to traditional whipple procedure.|PROCEDURE: Conventional whipple procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of HLX04-O in Subjects With wAMD
Status: COMPLETED
Conditions: Age Related Macular Degeneration
Interventions: DRUG: recombinant anti-vascular endothelial growth factor (VEGF) humanized monoclonal antibody ophthalmic injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Study of Different Trigger Modes of Antagonist Regimen in Patients With Low Ovarian Reserve
Status: UNKNOWN
Conditions: Poor Ovarian Response
Interventions: DRUG: Ovidrel|DRUG: Troprilin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CPI-613 and Fluorouracil in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Mucinous Adenocarcinoma of the Colon|Mucinous Adenocarcinoma of the Rectum|Recurrent Colon Cancer|Recurrent Rectal Cancer|Signet Ring Adenocarcinoma of the Colon|Signet Ring Adenocarcinoma of the Rectum|Stage IIIA Colon Cancer|Stage IIIA Rectal Cancer|Stage IIIB Colon Cancer|Stage IIIB Rectal Cancer|Stage IIIC Colon Cancer|Stage IIIC Rectal Cancer|Stage IVA Colon Cancer|Stage IVA Rectal Cancer|Stage IVB Colon Cancer|Stage IVB Rectal Cancer
Interventions: DRUG: 6,8-bis(benzylthio)octanoic acid|DRUG: fluorouracil|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sepsis in Neutropenic Patients: Autologous Stem Cell Transplantation as Model: a Transcriptomic Approach
Status: UNKNOWN
Conditions: Sepsis in Neutropenic Patients
Interventions: BIOLOGICAL: blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Mobic® Ampoules in the Initiation of Treatment of Painful Exacerbations of Osteoarthritis, Rheumatoid Arthritis and Other Similar Painful Inflammatory Conditions
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Meloxicam
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Central Jugular Vein Catheter Lumen Holder Design and Ergonomic Use
Status: NOT_YET_RECRUITING
Conditions: Central Venous Catheterization
Interventions: OTHER: Central Jugular Vein Catheter Lumen Holder Apparatus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: MBCT and CBT for Youth at High Risk for Mood and Psychotic Disorders: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Mood Disorders|Prodromal Symptoms|Bipolar Disorder|Parents|Clinical High Risk
Interventions: BEHAVIORAL: cognitive behavioral therapy|BEHAVIORAL: mindfulness-based cognitive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study to Evaluate Efficacy and Safety of Lenzilumab in Patients With COVID-19
Status: UNKNOWN
Conditions: Coronavirus Disease 2019 (COVID-19) Pneumonia
Interventions: BIOLOGICAL: Lenzilumab|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab at Low dosE for neuromyelitiS optiCa spectrUm disordEr (RESCUE)
Status: COMPLETED
Conditions: Neuromyelitis Optica Spectrum Disorder
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Saline Pre-hydration in Patients Undergoing Outpatient Colonoscopy
Status: COMPLETED
Conditions: Colonic Diseases
Interventions: DRUG: Infusion of 1 litre of normal saline before colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Function of Nutrition Rich Vegan Drink on Inflammatory Bowel Disease
Status: UNKNOWN
Conditions: Recovery
Interventions: DIETARY_SUPPLEMENT: Vegan drink|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of a Multi-component Physical Training in Hyper-fragile Elders: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Multimodal Intervention|Fragility|Other Metabolic Diseases|Physical Activity|Patient Fall|Dietary Modification
Interventions: OTHER: Control Intervention|OTHER: Multimodal Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FMISO PET Study of Glioblastoma
Status: COMPLETED
Conditions: Recurrent Glioblastoma
Interventions: DEVICE: FMISO PET|DEVICE: MRI|DRUG: Bevacizumab|DRUG: CCNU
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Cohort Study to Determine the Incidence of Dengue Fever and to Build Capacity for Dengue Vaccine Trials in Dengue-endemic Regions of South Asia
Status: COMPLETED
Conditions: Dengue
Interventions: PROCEDURE: Blood sample collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Effectiveness of Night Orthosis in Treating Women With Symptomatic Osteoarthritis in the Interphalangeal Joint of the Dominant Hand
Status: COMPLETED
Conditions: Hand Injuries
Interventions: DEVICE: Orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Lot Consistency Study of Trivalent Hemagglutinin Nanoparticle Influenza Vaccine
Status: NOT_YET_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: tNIV 1 and Matrix-M Adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Ashwagandha: Effects on Stress, Inflammation and Immune Cell Activation
Status: COMPLETED
Conditions: Inflammation|Cancer|Autoimmune Diseases
Interventions: DIETARY_SUPPLEMENT: Ashwagandha
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation Of Deep Anterior Lamellar Keratoplasty By Anterior Segment Ocular Coherence Tomography
Status: NOT_YET_RECRUITING
Conditions: Keratoconus|Cornea|Corneal Opacity
Interventions: PROCEDURE: deep anterior lamellar keratoplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Oral HBI-8000 in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)
Status: COMPLETED
Conditions: Peripheral T-Cell Lymphoma (PTCL)
Interventions: DRUG: HBI-8000
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a Non-invasive Hemoglobin Measurement Device in Pregnancy and Postpartum in Kenya, Pakistan, and Zambia
Status: ACTIVE_NOT_RECRUITING
Conditions: Pregnancy, High Risk
Interventions: DEVICE: Masimo Total Hemoglobin SpHb® Continuous Non-invasive Hemoglobin Monitoring Device|DIAGNOSTIC_TEST: Complete Blood Count
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness, Safety, and Tolerability Study of Oxymorphone Immediate Release (IR) Oral Liquid in Post Surgical Pediatric Subjects
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: oxymorphone HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep Apnea, Neurocognitive Decline and Brain Imaging in Patients With Subjective or Mild Cognitive Impairment
Status: RECRUITING
Conditions: Obstructive Sleep Apnea|Mild Cognitive Impairment|Subjective Cognitive Impairment
Interventions: DEVICE: Continuous Positive Airway Pressure or other management for OSA per clinical indications.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose-Ranging Study Of GSK233705B In Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK233705 12.5mcg|DRUG: GSK233705 25mcg|DRUG: GSK233705 50mcg|DRUG: GSK233705 100mcg|DRUG: GSK233705 200mcg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Novel BET Inhibitor PLX51107 for Steroid-Refractory Acute GVHD
Status: TERMINATED
Conditions: Acute Graft Versus Host Disease|Steroid Refractory Graft Versus Host Disease
Interventions: DRUG: BRD4 Inhibitor PLX51107
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety, Pharmacokinetics, and Pharmacodynamics of DNL343 in Participants With Amyotrophic Lateral Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: DNL343|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PGL5001 Proof of Concept Study in Inflammatory Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: PGL5001|DRUG: Placebo|DRUG: PGL5001|DRUG: Placebo|DRUG: PGL5001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrapleural Bevacizumab Injection for Malignant Effusion in Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Malignant Pleural Effusion
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Lubiprostone in Adults With Mixed or Unsubtyped Irritable Bowel Syndrome
Status: TERMINATED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Lubiprostone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiotherapy Followed by Durvalumab With or Without Tremelimumab for Liver Cancer After Progression on PD-1 Inhibition
Status: RECRUITING
Conditions: Advanced Hepatocellular Carcinoma|Stage III Hepatocellular Carcinoma AJCC v8|Stage IIIA Hepatocellular Carcinoma AJCC v8|Stage IIIB Hepatocellular Carcinoma AJCC v8|Stage IV Hepatocellular Carcinoma AJCC v8|Stage IVA Hepatocellular Carcinoma AJCC v8|Stage IVB Hepatocellular Carcinoma AJCC v8
Interventions: BIOLOGICAL: Durvalumab|RADIATION: Hypofractionated Radiation Therapy|BIOLOGICAL: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evolution of PET Fixation With FDG at the End of Antibiotic Treatment of Infective Endocarditis on Valvular Prosthesis
Status: NOT_YET_RECRUITING
Conditions: Prosthetic Valve Endocarditis
Interventions: RADIATION: FDG-PET at the end of treatment for IE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Permanent Resin Restorations Fabricated by Three Dimension Printer
Status: UNKNOWN
Conditions: Three-Dimensional Printing, Computer-Aided Design, Dental
Interventions: OTHER: Formlabs Permanent CB Resin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase III of COVID-19 Vaccine EuCorVac-19 in Healthy Adults Aged 18 Years and Older
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: EuCorVac-19|BIOLOGICAL: ChAdOx1 nCoV-19
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients With Esophageal and Gastric Cancer That Has Spread to a Limited Number of Other Places in the Body
Status: RECRUITING
Conditions: Clinical Stage IV Esophageal Adenocarcinoma AJCC v8|Clinical Stage IV Gastric Cancer AJCC v8|Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8|Clinical Stage IVA Gastric Cancer AJCC v8|Clinical Stage IVB Esophageal Adenocarcinoma AJCC v8|Clinical Stage IVB Gastric Cancer AJCC v8|Metastatic Esophageal Adenocarcinoma|Metastatic Gastric Adenocarcinoma|Oligometastatic Esophageal Adenocarcinoma|Oligometastatic Gastric Adenocarcinoma|Pathologic Stage IV Esophageal Adenocarcinoma AJCC v8|Pathologic Stage IV Gastric Cancer AJCC v8|Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8|Pathologic Stage IVB Esophageal Adenocarcinoma AJCC v8
Interventions: DRUG: Capecitabine|DRUG: Fluorouracil|DRUG: Leucovorin|DRUG: Leucovorin Calcium|DRUG: Oxaliplatin|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Quality of Life in Nursing Home Residents: A Cluster Randomized Clinical Trial of Efficacy
Status: COMPLETED
Conditions: Quality of Life
Interventions: BEHAVIORAL: Communication|BEHAVIORAL: Systematic Pain Assessment and Treatment|BEHAVIORAL: Medication Review|BEHAVIORAL: Occupational therapy|BEHAVIORAL: Safety
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Low Level Laser Therapy to Reduce Body Circumference in Obese Individuals
Status: COMPLETED
Conditions: Obesity
Interventions: DEVICE: Erchonia Obesity Laser|DEVICE: Placebo Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sublingual Fentanyl for the Management of Breakthrough Pain
Status: TERMINATED
Conditions: Advanced Cancers
Interventions: DRUG: Fentanyl Sublingual Spray (FSS)|BEHAVIORAL: Questionnaires|BEHAVIORAL: Mental Ability Tests|BEHAVIORAL: Study Diary
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of Three Doses of PT001 in Japanese Subjects With Moderate to Severe COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Glycopyrronium MDI 28.8 micrograms|DRUG: Glycopyrronium MDI 14.4 micrograms|DRUG: Glycopyrronium MDI 7.2 micrograms|DRUG: Placebo MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Intensity Extracorporeal Shockwave Therapy (LI-ESWT) by 'Renova' for Patients With Erectile Dysfunction
Status: COMPLETED
Conditions: Vasculogenic Erectile Dysfunction
Interventions: DEVICE: Shockwave system|DEVICE: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Strategies to Accelerate Evidence-Based Psychotherapy (EBP) Implementation in Military Settings
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Targeted Assessment and Context-Tailored Implementation of Change Strategies (TACTICS)|BEHAVIORAL: Prolonged exposure training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Multispectral Digital Colposcope With Probe for Detection of Cervical Intraepithelial Neoplasia
Status: UNKNOWN
Conditions: Carcinoma in Situ of Uterine Cervix|Cervical Intraepithelial Neoplasias|High Grade Cervical Intraepithelial Neoplasia
Interventions: DEVICE: Multispectral Digital Colposcope with probe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cisplatin, CPT-11 and Celecoxib With Radiation Therapy and Surgery for Operable Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: Cisplatin|DRUG: Irinotecan|DRUG: Celecoxib|PROCEDURE: Radiation Therapy|PROCEDURE: Esophagectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Fermented Food Intervention Among Locally Advanced Rectal Cancer Patients (The FEED Trial)
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: OTHER: FEED-FF|OTHER: Standard of Care (SUC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Human Volunteer Study Investigating Single Oral Doses of GSK598809 in Otherwise Healthy Smokers
Status: COMPLETED
Conditions: Substance Dependence
Interventions: DRUG: GSK598809|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Collaborative Power Mobility Innovative Learning OpporTunity (CoPILOT) - A Pilot Study of a New Training Approach (Phase 2)
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: CoPILOT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Remdesivir (GS-5734™) Treatment of Coronavirus Disease 2019 (COVID-19) in an Outpatient Setting
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: RDV|DRUG: Placebo to Match RDV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test How Well Multiple Doses of BI 765423 Are Tolerated by Healthy Men
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: BI 765423|DRUG: Placebo matching BI 765423
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effects of a Theanine Formulation on Stress, Burnout, Mood, and Sleep in Individuals Who Report Occasional Moderate or High Levels of Stress
Status: TERMINATED
Conditions: Stress
Interventions: DIETARY_SUPPLEMENT: Theanine Formulation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Refractory Obsessive Compulsive Disorder With rTMS
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: DEVICE: refractory transcranial magnetic stimulation (rTMS)|DEVICE: Sham condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Flavanol-rich Cocoa on Digestive and Cerebrovascular Health in the Colombian Adults
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers
Interventions: OTHER: Commercial cocoa|OTHER: High flavonols Cocoa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Right Lateral Positioning of Postoperative Pediatric Cardiac Surgery
Status: UNKNOWN
Conditions: Heart Defects, Congenital
Interventions: PROCEDURE: Right lateral position (2 hours)|PROCEDURE: Left lateral position (30 minutes)|PROCEDURE: Supine position (30 minutes)|PROCEDURE: Left lateral position (2 hours)|PROCEDURE: Supine position (2 hours)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using Immersive Virtual Reality for Children's Lower Limb Rehabilitation
Status: COMPLETED
Conditions: Virtual Reality|Physical Rehabilitation|Lower Limb Injury|Paediatric
Interventions: DEVICE: Immersive Virtual Reality Lower Limb and Knee Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Brain Controlled Spinal Cord Stimulation In Participants With Spinal Cord Injury For Lower Limb Rehabilitation
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries|Paraplegia
Interventions: DEVICE: ARC-BSI Lumbar system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Controlled Trial of an Intervention for Preschool Children With Autism: TEACCH
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: TEACCH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of Manidipine Versus Amlodipine and the Combination of Manidipine Plus Delapril Versus Amlodipine Plus Delapril on Intraglomerular Pressure in Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: amlodipine 10 mg|DRUG: manidipine 20 mg|DRUG: amlodipine 5 mg + delapril 30 mg|DRUG: manidipine 10 mg + delapril 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Sirolimus Versus Mycophenolate Liver Transplant Recipients With Recurrent Hepatitis C Virus (HCV)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Mycophenolate to sirolimus switch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: N-3 Polyunsaturated Fatty Acids Prevent Postoperative Recurrence of Crohn's Disease
Status: UNKNOWN
Conditions: Inflammatory Bowel Diseases|Crohn Disease|Polyunsaturated Acid Lipidosis
Interventions: DRUG: azathioprine|DRUG: infliximab|DRUG: N-3 Polyunsaturated Fatty Acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Aim of This Study is to Examine the Effect of Intravenously Administered Tranexamic Acid (TXA) on the Visual Clarity, Perioperative Hemorrhage, Duration and Early Postoperative Course of Shoulder Arthroscopy in Beach Chair Position.
Status: COMPLETED
Conditions: Rotator Cuff Tears|Hemorrhage, Surgical|Shoulder Injuries
Interventions: DRUG: Tranexamic Acid Injectable Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dopaminergic Therapy for Frontotemporal Dementia Patients
Status: UNKNOWN
Conditions: Frontotemporal Dementia|Dementia|Aphasia, Primary Progressive|Pick Disease of the Brain|Brain Diseases|Central Nervous System Diseases|Nervous System Diseases|Neurocognitive Disorders|Mental Disorders|Neurodegenerative Diseases|Frontotemporal Lobar Degeneration|TDP-43 Proteinopathies|Proteostasis Deficiencies|Metabolic Disease|Aphasia|Speech Disorders|Language Disorders|Communication Disorders|Neurobehavioral Manifestations|Neurologic Manifestations
Interventions: DRUG: Rotigotine 4Mg/24Hrs Patch|DRUG: Rotigotine 6Mg/24Hrs Patch|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Puressentiel Protective Nasal Spray in Allergic Rhinitis
Status: UNKNOWN
Conditions: Allergic Rhinitis Due to Grass Pollen|Allergic Inflammation
Interventions: DEVICE: Puressentiel protective nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Reducing Suicidal Ideation Through Treatment of Nightmares-Post Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder|Suicidal Ideation|Nightmares
Interventions: DRUG: Prazosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Therapeutic Equivalence Study of Two Oxiconazole Nitrate Topical Cream Treatments for Patients With Tinea Pedis
Status: COMPLETED
Conditions: Tinea Pedis
Interventions: DRUG: Oxiconazole Nitrate Cream 1%|DRUG: Oxiconazole Nitrate Cream 1% (Oxistat®)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Contezolid Acefosamil and Contezolid Compared to Linezolid Administered Intravenously and Orally to Adults With Moderate or Severe Diabetic Foot Infections (DFI)
Status: RECRUITING
Conditions: Diabetic Foot Infection
Interventions: DRUG: contezolid acefosamil (IV)/contezolid (PO)|DRUG: Linezolid (IV and PO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of ISV-303 to DuraSite Vehicle in Cataract Surgery Subjects
Status: COMPLETED
Conditions: Ocular Inflammation
Interventions: DRUG: ISV-303|OTHER: DuraSite Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of IVB102 Injection in Subjects With X-linked Retinoschisis
Status: RECRUITING
Conditions: Retinoschisis|Retinal Disease|Retinal Degeneration|Eye Diseases
Interventions: GENETIC: IVB102 Injection|GENETIC: IVB102 Injection|GENETIC: IVB102 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of (Balance, Resistance, Aerobic and Cognitive Exercises) & (Balance Resistance Exercise)
Status: COMPLETED
Conditions: Elderly Population
Interventions: OTHER: Balance, Resistance, Aerobic, Cognition Exercises (BRACE)|OTHER: Balance Resistance Exercise (BRE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Water Oxygenation and Brain Activity
Status: COMPLETED
Conditions: Muscle Damage
Interventions: DIETARY_SUPPLEMENT: Control Unmodified Placebo Water|DIETARY_SUPPLEMENT: Electrokinetically modified water (EMW)|DIETARY_SUPPLEMENT: Electrokinetically modified water (EMW)|DIETARY_SUPPLEMENT: Control Unmodified Placebo Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Liposome Vitamin C on the Absorption and Metabolism of the Human Body.
Status: COMPLETED
Conditions: Vitamin C Deficiency
Interventions: DIETARY_SUPPLEMENT: vitamin C without liposome|DIETARY_SUPPLEMENT: liposomal process A vitamin C|DIETARY_SUPPLEMENT: liposomal process B vitamin C (Double Nutri™)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation (DBS) for Early Stage Parkinson's Disease (PD)
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DEVICE: B-STN DBS|DRUG: Optimal drug therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Patient-Driven Transfusion Thresholds in Hematological Disorders: A Pilot Study
Status: WITHDRAWN
Conditions: Anemia|Aplastic Anemia|Bone Marrow Failure|Hematopoietic and Lymphoid Cell Neoplasm|Leukemia|Myelodysplastic Syndrome
Interventions: PROCEDURE: Red Blood Cell Transfusions (RBCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multiple Ascending Dose Study of MEDI7247 in Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer Squamous (NSCLC-Sq)|Head and Neck Squamous Cell Carcinoma (HNSCC)|Small Cell Lung Cancer (SCLC)|Pancreatic Ductal Adenocarcinoma (PDAC)|Colorectal Cancer (CRC)|Metastatic Castration-resistant Prostate Cancer (mCRPC)
Interventions: DRUG: MEDI7247
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spices Inhibit the Formation and Absorption of Malondialdehyde From Hamburger Meat
Status: COMPLETED
Conditions: NIDDM
Interventions: OTHER: Hamburger meat patty with salt|OTHER: Hamburger meat patty with spice blend
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ESS505 Pre-hysterectomy Protocol
Status: COMPLETED
Conditions: Contraception
Interventions: DEVICE: ESS505 (Essure, BAY1454033)|DEVICE: ESS305 (Essure, BAY1454032)|DEVICE: ESS505-A (Essure, BAY1454033)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Testing the Addition of the Drug Relugolix to the Usual Radiation Therapy for Advanced-Stage Prostate Cancer
Status: RECRUITING
Conditions: Oligometastatic Prostate Carcinoma|Prostate Adenocarcinoma|Stage IVB Prostate Cancer AJCC v8
Interventions: DRUG: Placebo Administration|OTHER: Quality-of-Life Assessment|DRUG: Relugolix|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Phase IIa Efficacy and Safety Study of Radium-223 Dichloride With Abiraterone Acetate or Enzalutamide in Metastatic Castration-resistant Prostate Cancer (CRPC)
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Radium-223 dichloride (Xofigo, BAY88-8223)|DRUG: Abiraterone acetate|DRUG: Prednisone|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Efficacy of Brief Behavior Change Counseling on Lifestyle in Hypertensive and Diabetics Participants
Status: UNKNOWN
Conditions: Hypertension|Diabetes|Life Style
Interventions: BEHAVIORAL: BBCC+5A's+GS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A French Multicenter Observational Retrospective Study of Rare Primary Liver Cancers
Status: RECRUITING
Conditions: Hepatocholangiocarcinoma|Fibrolamellar Carcinoma|Hepatic Epithelioid Hemangioendothelioma|Hepatoblastoma|Hepatic Neuroendocrine Carcinoma|Hepatic Carcinosarcomas|Hepatic Cystadenoma|Hepatic Leiomyosarcomas|Hepatic Angiosarcomas|Cholangiocarcinoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Cycled Light on Premature Infants and Mothers
Status: UNKNOWN
Conditions: Preterm Infant Development|Retinopathy of Prematurity|Sleep Quality|Quality of Life
Interventions: BEHAVIORAL: Cycled light Experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beta-Blocker Influences on Inflammatory and Neural Responses to Stress
Status: RECRUITING
Conditions: Cardiovascular Disease
Interventions: DRUG: Propranolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Efficacy, and Pharmacokinetics (PK) of Daptomycin (MK-3009) in Japanese Pediatric Subjects With Complicated Skin and Soft Tissue Infections (cSSTI) and Bacteremia (MK-3009-029)
Status: COMPLETED
Conditions: Bacteremia|Soft Tissue Infections|Skin Diseases, Infectious
Interventions: DRUG: Daptomycin for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COREG MR Versus TOPROL-XL On The Lipid Profile Of Normolipidemic Or Mildly Dyslipidemic Patients With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Carvedilol Phosphate modified release formulation|DRUG: metoprolol succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Testing Patient Decision Tools Related to the Risks and Benefits of Weight Loss Surgery
Status: COMPLETED
Conditions: Obesity, Morbid|Obesity|Decision Aids|Bariatric Surgery
Interventions: OTHER: Video Decision Aid|OTHER: Booklet Decision Aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Clinical Trial to Evaluate the Effectiveness of an Acne Serum in Improving Facial Acne and Post-Acne Pigmentation
Status: COMPLETED
Conditions: Acne
Interventions: OTHER: Rael Miracle Clear Complete Acne Serum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Can B12 and Folate Levels Predict HPV Penetration in Patients With ASCUS?
Status: COMPLETED
Conditions: ASC-US|Human Papilloma Virus
Interventions: DIETARY_SUPPLEMENT: Vitamin B12 and folate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC