pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Bioimpedance Spectroscopy in Humans During Acute Fluid Volume Expansion With Different Crystalloid Solutions
Status: COMPLETED
Conditions: HEALTHY
Interventions: OTHER: Treatment with 0.9% normal saline|OTHER: Treatment with D5+ 0.45 saline|OTHER: Treatment with D5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Safety & Efficacy of Imatinib for the Treatment of SARS-COV-2 Induced Pneumonia
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Imatinib Mesylate|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methylene Blue in Severe Sepsis and Septic Shock
Status: UNKNOWN
Conditions: Severe Sepsis|Septic Shock
Interventions: DRUG: Intravenous methylene blue administration|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CD20-CD19 Compound CAR (cCAR) T Cells for Patients With Relapsed /Refractory B Cell Malignancies
Status: UNKNOWN
Conditions: B Cell Lymphoma|B Cell Leukemia
Interventions: BIOLOGICAL: CD20-CD19 cCAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Trial of High-dose Ascorbate for Pancreatic Cancer (PACMAN 2.1)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Neoplasms|Cancer of Pancreas|Cancer of the Pancreas|Neoplasms, Pancreatic|Pancreas Cancer|Pancreas Neoplasms|Adenocarcinoma
Interventions: DRUG: Gemcitabine|DRUG: nab-paclitaxel|DRUG: Pharmacological ascorbate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erythropoietin and Iron Supplementation for Patients With Chemotherapy-induced Anaemia
Status: UNKNOWN
Conditions: Chemotherapy-induced Anaemia
Interventions: DRUG: Erythropoietins (EPO)|DRUG: Aggressive iron dextran supplementation|DRUG: Erythropoietins (EPO)|DRUG: Sustained iron dextran supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ia/Ib Talazoparib + Tazemetostat for mCRPC
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Prostate Cancer|Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Talazoparib|DRUG: Tazemetostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Sleep Onset: the Power of Tactile Breath Pacer in Cognitive Behavioral Therapy for Insomnia
Status: NOT_YET_RECRUITING
Conditions: Primary Insomnia
Interventions: DEVICE: Moonbird|BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EBUS-TBNA vs EUS-B-FNA for Needle Aspiration of Mediastinal Lesions
Status: COMPLETED
Conditions: Mediastinum
Interventions: DEVICE: EBUS-TBNA|DEVICE: EUS-B-FNA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Investigating the Effect of Obicetrapib on Lipoprotein Metabolism
Status: ACTIVE_NOT_RECRUITING
Conditions: Lipid Metabolism
Interventions: DRUG: Obicetrapib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention Development and Pilot Study to Prevent Untreated Native Hawaiian and Pacific Islander Opioid Use Disorder
Status: UNKNOWN
Conditions: Opioid-use Disorder
Interventions: BEHAVIORAL: Treatment Seeking Intervention for Pacific Islanders with Opioid Use Disorders
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of CA-4948 in Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma
Status: RECRUITING
Conditions: Relapsed Hematologic Malignancy|Refractory Hematologic Malignancy|Relapsed Primary Central Nervous System Lymphoma|Refractory Primary Central Nervous System Lymphoma
Interventions: DRUG: Emavusertib|DRUG: ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sertraline and Cytosine Arabinoside in Adults With Relapsed and Refractory AML
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Sertraline|DRUG: Cytosine arabinoside|PROCEDURE: allogeneic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vibration on Muscle Properties, Physical Activity and Balance in Children With Cerebral Palsy
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Palsy, Spastic
Interventions: DEVICE: Vibration Platform|DEVICE: Placebo Platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Compare Pharmacokinetic (PK) Profiles of Naproxen Sodium, Diphenhydramine Hydrochloride, and Naproxen Sodium and Diphenhydramine Hydrochloride Combination
Status: COMPLETED
Conditions: Therapeutic Equivalence
Interventions: DRUG: BAY98-7111|DRUG: Naproxen Sodium (Aleve, BAYH6689)|DRUG: Diphenhydramine HCl|DRUG: BAY98-7111
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Health Coaching-Based Navigation at the Conclusion of Treatment for the Support of Black Breast Cancer Survivors
Status: RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions: BEHAVIORAL: Patient Navigation|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Enteral Nutrition and Glycemic Variability Neurological Intensive Care Unit Study
Status: TERMINATED
Conditions: Subarachnoid Hemorrhage|Intracranial Hemorrhage|Ischemic Strokes|Subdural Hematoma
Interventions: DIETARY_SUPPLEMENT: Glycerna|DIETARY_SUPPLEMENT: Jevity - Control Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Conservative vs Surgical Treatment for Proximal Humerus Fractures in the Elderly
Status: UNKNOWN
Conditions: Shoulder Fractures
Interventions: PROCEDURE: Osteosynthesis with locking plate|PROCEDURE: Sling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pilates Exercises Versus Pelvic Floor Muscle Exercises Among Elderly Women With Urinary Incontinence
Status: RECRUITING
Conditions: Urinary Incontinence
Interventions: OTHER: Shoulder bridge|OTHER: Clam shell|OTHER: Scissors|OTHER: Adductor squeeze|OTHER: Pelvic clock supine|OTHER: urine hold and tummy tuck in|OTHER: Bridging|OTHER: Split table top|DEVICE: Electrical muscle stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of RADPLAT and Tarceva in Locally Advanced Head and Neck Squamous Cell Carcinoma (SCCA)
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Erlotinib (Tarceva)|DRUG: Intra-arterial Cisplatin (PLAT)|RADIATION: Radiation Therapy (RAD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Ketamine Has no Preemptive Analgesic Effect in Patients Undergoing Colon Surgery.
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Prospective Clinical Study of Ruxolitinib and Etoposide Combined With DDGP Regimen (RUE-DDGP) in Induction Therapy of T/NK Cell Lymphoma-associated Hemophagocytic Syndrome.
Status: UNKNOWN
Conditions: Hemophagocytic Syndrome|T/NK-Cell Lymphoma
Interventions: DRUG: Ruxolitinib, Etoposide, Dexamethasone, Gemcitabine, Pegaspargase, cis-platinum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Progressive Pulmonary Fibrosis
Status: RECRUITING
Conditions: Progressive Pulmonary Fibrosis
Interventions: DRUG: BMS-986278|DRUG: BMS-986278 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of COVID-19 Pandemic on Adolescent and Young Adult Cancer Patients and Survivors
Status: RECRUITING
Conditions: COVID-19 Infection|Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Survey Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Targeted Busulfan, Fludarabine, Etoposide Conditioning Regimen for HSCT in Childhood and Adolescent ALL.
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Busulfan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Advances in Telephone-based Cognitive Screening Procedures
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis|Alzheimer's Disease|Lewy Body Dementia|Frontotemporal Degeneration|Cerebrovascular Disorders
Interventions: BEHAVIORAL: Telephone-based neuropsychological assessment - ALS|BEHAVIORAL: Telephone-based neuropsychological assessment - AD, LBD, FTD and CVD|BEHAVIORAL: Telephone-based and in-person cognitive screening - NIs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Hemocompatibility of the Direct Oral Anti-Coagulant Apixaban in Left Ventricular Assist Devices
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Apixaban|DRUG: Warfarin|DEVICE: LVAD implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Feasibility Evaluation of the Gentuity HF-OCT Imaging System With Vis-M Micro-Imaging Catheter
Status: RECRUITING
Conditions: Anatomy
Interventions: DEVICE: HF-OCT Imaging System with Vis-M Micro-Imaging Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effectiveness of an Intervention to Reduce Driving Under the Influence of Alcohol Among Drivers
Status: UNKNOWN
Conditions: Alcohol Consumption|Traffic Accident|Risk Perception of Driving After Alcohol Consumption
Interventions: BEHAVIORAL: Brief intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety Study of the Switch From Oral Selexipag to Intravenous Selexipag in Subjects With Stable Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: i.v. selexipag|DRUG: oral selexipag (Uptravi)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple-Dose PK Study to Evaluate the Comparative Bioavailability of PrimeC Tablets to Ciprofloxacin Tablets Co-administered With Celecoxib Capsules, in Healthy Adult Subject
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: PrimeC 748 mg|DRUG: Ciprofloxacin 750 MG|DRUG: Celecoxib 200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prehabilitation to Enhance Postoperative Functional Capacity Following Radical Cystectomy
Status: COMPLETED
Conditions: Bladder Cancer|Entire Ileal Conduit|Urinary Bladder Cancer
Interventions: OTHER: Prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Mitoxantrone Hydrochloride Liposome Injection in Chinese Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: Mitoxantrone Hydrochloride Liposome injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiotherapy for Wet AMD (STAR)
Status: ACTIVE_NOT_RECRUITING
Conditions: Neovascular (Wet) Age-related Macular Degeneration (AMD)
Interventions: RADIATION: Stereotactic radiotherapy (16 Gray or Sham)|DRUG: 0.5 mg ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Test the Effects of Adding 1 of 2 New Treatment Agents to Commonly Used Chemotherapy Combinations
Status: UNKNOWN
Conditions: Acute Myeloid Leukaemia|Myelodysplastic Syndrome
Interventions: DRUG: Arm A Mylotarg plus DA Versus CPX-351|DRUG: Arm B Vosaroxin and Decitabine|DRUG: Arm D Small molecule or Not|DRUG: Arm C DA V FLAG-Ida V DAC|DRUG: Arm E CPX-351 (200 V 300)|DRUG: Arm F DA V IDAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subventricular Zone (SVZ) and Temozolomide in Glioblastoma Multiforme
Status: RECRUITING
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Temozolomide|RADIATION: Subventricular Zone radiation|RADIATION: Neural Progenitor Cell Sparing radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Data on Oral Contraceptives Compliance in Non Stop Regimen
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Qlaira or Yaz (BSP products defined as Combined Oral Contraceptive) and Cerazette or Azalia (competitor's products defined as Progestogen Only Pill)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Nexavar/Placebo as Maintenance Therapy for Patients With Advanced Ovarian or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasms
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Cogane (PYM50028) in Early-stage Parkinson's Disease (CONFIDENT-PD)
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: PYM50028|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Emerging New Treatments for Infection Prevention in Total Joint Replacement
Status: ACTIVE_NOT_RECRUITING
Conditions: Periprosthetic Joint Infection|Draining Wound
Interventions: DRUG: Povidone-Iodine Lavage Solution|DRUG: Chlorhexidine Lavage Solution|DRUG: Topical Antibiotic|DRUG: Saline Lavage Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study on Decitabine Plus Carboplatin Versus Physician's Choice Chemotherapy in Recurrent, Platinum-resistant Ovarian Cancer.
Status: UNKNOWN
Conditions: Recurrent, Platinum-resistant Ovarian Cancer
Interventions: DRUG: Decitabine|DRUG: Carboplatin|DRUG: Pegylated Liposomal Doxorubicin|DRUG: Gemcitabine|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interaction Study to Evaluate the Effects of Mefenamic Acid on the Pharmacokinetics and Pharmacodynamics of Sotagliflozin in Healthy Male and Female Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Sotagliflozin (SAR439954)|DRUG: Mefenamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: SLS-005 (Trehalose Injection) in the Treatment of Alzheimer's Disease
Status: WITHDRAWN
Conditions: Alzheimer's Disease
Interventions: DRUG: SLS-005 - Once Weekly|DRUG: SLS-005 - Twice Weekly
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: F@ce 2.0 - Information and Communication Technology-based Rehabilitation Intervention After Stroke in Sweden
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Mobile phone supported and team based rehabilitation|BEHAVIORAL: Rehabilitation as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PD-1 Inhibitor Plus Anti-EGFR Therapy And Radiotherapy in Locally Advanced NPC Resistant to Induction Chemotherapy
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: COMBINATION_PRODUCT: Anti-EGFR and PD-1 inhibitor arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double Cord Versus Haploidentical (BMT CTN 1101)
Status: COMPLETED
Conditions: Acute Lymphocytic Leukemia|Acute Myelogenous Leukemia|Burkitt's Lymphoma|Follicular Lymphoma|Hodgkin Lymphoma|Mantle Cell Lymphoma|Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: Haploidentical Bone Marrow Transplant|BIOLOGICAL: Double Umbilical Cord Blood Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Vagal Dysfunction on Gastrointestinal and Inflammatory Pathways in HIV
Status: RECRUITING
Conditions: HIV|Non-HIV|Vagus Nerve Dysfunction
Interventions: DRUG: Pyridostigmine|DRUG: Placebos|PROCEDURE: non-invasive vagal nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Outcome in Subarachnoid Hemorrhage wIth Nadroparine
Status: RECRUITING
Conditions: Aneurysmal Subarachnoid Hemorrhage|Delayed Cerebral Ischemia
Interventions: DRUG: Nadroparin Injectable Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Zero-fluoroscopy Approach Versus Fluoroscopic Approach for the Ablation of Paroxysmal Supraventricular Tachycardia
Status: COMPLETED
Conditions: Paroxysmal Supraventricular Tachycardia
Interventions: DEVICE: Zero-fluoroscopic ablation|DEVICE: Conventional fluoroscopic ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Trial of Metformin for Glucose Intolerance or Increased BMI in Prostate Cancer Patients
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Metformin|BEHAVIORAL: Lifestyle Modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise Oncology Intervention in Fitness Capacity and Body Composition in Breast Cancer Survivals
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Exercise Oncology|Cancer Survivors|Fitness Capacity
Interventions: OTHER: Oncological physical exercise intervention|OTHER: Active Physical Activities intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bone Tissue Engineering Using Autologous Bone Repair Cell (BRC) Therapy for Sinus Floor Bone Augmentation
Status: COMPLETED
Conditions: Tooth Loss
Interventions: PROCEDURE: Sinus lift augmentation and dental implant|BIOLOGICAL: Aastrom BRCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Voriconazole With or Without Interferon Gamma in Treating Patients With Aspergillosis or Other Fungal Infections
Status: COMPLETED
Conditions: Infection|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: recombinant interferon gamma|DRUG: voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Random Clinical Trial (RCT) of the Impact of Electrocoagulation on Ovarian Reserve
Status: COMPLETED
Conditions: Ovarian Cyst
Interventions: PROCEDURE: Laparoscopic ovarian cystectomy using bipolar|PROCEDURE: Laparoscopic ovarian cystectomy using ultrasonic scalpel|PROCEDURE: Laparoscopic ovarian cystectomy using suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Tacrolimus in Refractory Rheumatoid Arthritis Patients for 6 Months and Long-term Treatment
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Tacrolimus|DRUG: MTX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open, Non-comparative, Multi-centre Post Marketing Clinical Follow-up Investigation to Evaluate Performance and Safety on Diabetic Foot Ulcer, DFU When Using Fast Gelling Dressing as Intended.
Status: COMPLETED
Conditions: Diabetic Foot Ulcers
Interventions: DEVICE: Fast gelling dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Guided Tissue Regeneration Membrane in the Healing of Apicomarginal Defects
Status: COMPLETED
Conditions: Apicomarginal Defects
Interventions: PROCEDURE: Peripical surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Auricular Acupressure Versus Intermittent Dietary Restriction in Children With Gastric Heat and Dampness Obstruction
Status: RECRUITING
Conditions: Obesity, Childhood
Interventions: OTHER: Auricular acupressure of traditional Chinese Medicine|BEHAVIORAL: Intermittent low carbohydrate diet|BEHAVIORAL: Health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Serologic Assay Validation, Proficiency Testing, Safety and Immunogenicity of Norovirus GI.1/GII.4 Bivalent Virus-Like Particle Vaccine
Status: COMPLETED
Conditions: Norovirus|Healthy Participants
Interventions: BIOLOGICAL: NoV GI.1/GII.4 Bivalent VLP Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Romidepsin in Treating Patients With Steroid-Refractory Graft-versus-Host Disease
Status: TERMINATED
Conditions: Graft Versus Host Disease
Interventions: DRUG: romidepsin|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fluphenazine Hydrochloride for Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Fluphenazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Consumption of Bread Types Made From Various Flours on Blood Glucose Fluctuations
Status: COMPLETED
Conditions: Obesity|Glycemic Index|Blood Glucose|Bread
Interventions: DIETARY_SUPPLEMENT: Bread consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: One Year Clinical Evaluation of Milled BioHPP (PEEK) Versus Zirconia Veneered Single Crowns (RCT-one-year Evaluation).
Status: UNKNOWN
Conditions: Carious Tooth
Interventions: OTHER: BioHPP PEEK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Electrode Aggregometry to Assess Platelet Function in Patients Undergoing Hip Joint Alloplasty With and Without Bone Cement
Status: COMPLETED
Conditions: Arthroplasty|Methylmethacrylate Embolism|Platelet Aggregation
Interventions: OTHER: Blood sample 1|OTHER: Blood sample 2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Resvent RXiBreeze™ PAP System to Treat Obstructive Sleep Apnea
Status: NOT_YET_RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: RXiBreeze PAP System, Model RXiBreeze 20A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Effects of Vitamin D in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Vitamin D Insufficiency
Interventions: DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of a Switch to Doravirine/Islatravir in Participants With HIV-1 (MK-8591A-017)
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infection
Interventions: DRUG: DOR/ISL|DRUG: ART
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Inflammation, Maldigestion and Symptoms Due to Commercial Milk and A2 Milk
Status: RECRUITING
Conditions: Lactose Intolerance
Interventions: OTHER: Milk containing A1 and A2 beta-casein|OTHER: Milk containing only A2 beta-casein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Treatment of Patients With Myelodysplastic Syndrome or Acute Myelocytic Leukemia With an Impending Hematological Relapse With Azacitidine (Vidaza)
Status: COMPLETED
Conditions: Acute Myelocytic Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrostimulation Therapies With Implementation of Multifractal Electromyographic Analysis
Status: UNKNOWN
Conditions: Temporomandibular Dysfunction (TMD)|Orofacial Pain
Interventions: COMBINATION_PRODUCT: Transcutaneus electrostimulation therapies|COMBINATION_PRODUCT: Percutaneus electrostimulation therapies|DIAGNOSTIC_TEST: Oclusal splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare Adjuvant Chemotherapy of Docetaxel/Capecitabine/Oxliplatin Versus Capecitabine/Oxaliplatin in Advanced Gastric Cancer at Stage IIIb and IV(KCSG ST15-08): TRIUMPH
Status: RECRUITING
Conditions: Gastric Cancer, Adjuvant Chemotherapy, XO
Interventions: DRUG: Docetaxel and capecitabine and oxaliplatin|DRUG: capecitabine and oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neo-Synalar Modified 48 Hour Patch Test
Status: COMPLETED
Conditions: Allergy
Interventions: DRUG: Neo-Synalar Cream|OTHER: Sodium Lauryl Sulfate Aqueous Solution (0.40%)|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Kinesiotaping and Physiotherapy in Grade 2 Osteoarthritis Following Degenerative Meniscal Tears
Status: COMPLETED
Conditions: Knee Osteoarthritis|Meniscus Tear
Interventions: DEVICE: Kinesiotaping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tiotropium and Salmeterol PK Study in COPD Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium+Salmeterol|DRUG: Salmeterol|DRUG: Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety Tolerability and Acceptability of Long Acting Injections of the Human Immunodeficiency Virus (HIV) Integrase Inhibitor, GSK1265744, in HIV Uninfected Men (ECLAIR)
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: 744 Tablet|DRUG: 744 LA Injection|DRUG: Placebo Tablet|DRUG: Placebo Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pragmatic Trial of Ambulatory Toxicity Management in Patients Receiving Adjuvant or Neo-adjuvant Chemotherapy for Early Stage Breast Cancer
Status: COMPLETED
Conditions: Early Stage Breast Cancer
Interventions: OTHER: Proactive Telephone Toxicity Management|OTHER: Control Arm|OTHER: PRO Sub-Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cholesterol-lowering Effects of nutraceuticaLs Versus Ezetimibe in Statin-intolerant Patients
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Ezetimibe|DIETARY_SUPPLEMENT: Nutraceuticals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Fish Oil in Critically Ill Cardiac Patients
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Fish oil emulsion|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Seaweed Derived Polyphenols on Inflammation and Oxidative Stress in Vivo - The SWAFAX Study
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Treatment capsule containing seaweed extract (treatment)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Efficacy and Safety of Using 3.0mg Liraglutide to Treat Weight Regain After Roux-en-Y Gastric Bypass Surgery
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Saxenda|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: An Intervention on Healthy Adults of Probiotics on Gut Flora Metabolisms of Choline
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: probiotics intervention|DIETARY_SUPPLEMENT: non-probiotic control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of the Braive Growth Modulation System for Progressive Pediatric Scoliosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Juvenile Idiopathic Scoliosis|Adolescent Idiopathic Scoliosis
Interventions: DEVICE: Braive™ Growth Modulation System (Braive™ GMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of CPX101 in Overweight and Obese Subjects Without Diabetes Mellitus
Status: RECRUITING
Conditions: Overweight and Obesity
Interventions: BIOLOGICAL: CPX101 or placebo 120mg Q2W|BIOLOGICAL: CPX101 or placebo 160mg Q4W|BIOLOGICAL: CPX101 or placebo 160mg Q2W|BIOLOGICAL: CPX101 or placebo 240mg Q4W|BIOLOGICAL: CPX101 or placebo 240mg Q2W
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety And Efficacy Study Of The Combination Of CpG 7909 And Herceptin In Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Carcinoma, Metastatic Breast
Interventions: DRUG: CPG 7909|DRUG: Herceptin®|DRUG: CPG 7909|DRUG: Herceptin®|DRUG: CPG 7909|DRUG: Herceptin®|DRUG: CPG 7909|DRUG: Herceptin®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Acupoint Stimulation on Postoperative Dizziness in Hemifacial Spasm Patients
Status: COMPLETED
Conditions: Transcutaneous Electrical Acupoint Stimulation|Hemifacial Spasm|Dizziness
Interventions: DEVICE: HANS 100B stimulator (4 conductors, 8 electrodes; Jisheng Co., Nanjing, China)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Empirical Versus Preemptive Antifungal Therapy
Status: COMPLETED
Conditions: Fungal Infection|Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: caspofungin acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Carbetocin Versus Oxytocin Infusion Plus Tranexamic Acid During Cesarean Section
Status: UNKNOWN
Conditions: Cesarean Section Complications
Interventions: DRUG: Carbetocin|DRUG: oxytocin|DRUG: TA|DRUG: placebo to carbetocin|DRUG: placebo to TA|DRUG: placebo to oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lymphatic Function in Patients With Fontan Circulation: Effect of Physical Training
Status: COMPLETED
Conditions: Univentricular Heart|Congenital Heart Disease|Lymphatic Abnormalities|Functional Capacity|Exercise Training|Quality of Life
Interventions: OTHER: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Endpoint Bioequivalence Study for Fluticasone Propionate and Salmeterol Xinafoate
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone / Salmeterol|DRUG: Placebo|DRUG: Advair Diskus 100/50
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prone Position Effects on Work of Breathing and Intrinsic PEEP in Children With Severe Acute Viral Bronchiolitis
Status: COMPLETED
Conditions: Severe Bronchiolitis
Interventions: PROCEDURE: Supine then Prone position|PROCEDURE: Prone then supine position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Frequency SARS for Neurogenic Bladder and Bowel Emptying
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DEVICE: Finetech-Brindley Sacral Anterior Roots Stimulation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Immunogenicity Evaluation of MTBVAC in Newborns in Sub-Saharan Africa
Status: RECRUITING
Conditions: Tuberculosis
Interventions: BIOLOGICAL: MTBVAC|BIOLOGICAL: BCG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Thoracic Extension Versus Thoracic Stabilization Exercises in Patients With Maigne's Thoracic Pain
Status: COMPLETED
Conditions: Thoracic
Interventions: OTHER: Conventional physical therapy treatment along with thoracic extension exercises|OTHER: Conventional physical therapy treatment along with thoracic stabilization exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carmustine Implants in Treating Patients With Brain Metastases
Status: COMPLETED
Conditions: Metastatic Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: polifeprosan 20 with carmustine implant|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of PRAX-944 in Participants With Essential Tremor
Status: COMPLETED
Conditions: Essential Tremor
Interventions: DRUG: Part A: 20 and 40 mg PRAX-944|DRUG: Part B: 120 mg PRAX-944|DRUG: Part B: 120 mg PRAX-944 and Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Goal-directed Fluid Therapy During Deep Inferior Epigastric Perforator (DIEP) Free Flap Breast Reconstruction
Status: RECRUITING
Conditions: Hypotension During Surgery
Interventions: DRUG: Plasma-lyte|DRUG: Norepinephrine|DRUG: Plasma-lyte|DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Prevalence of Sarcopenia in a Cohort of Haemodialysis Patients and Its Correlation With Mortality
Status: COMPLETED
Conditions: End-stage Kidney Disease|End-stage Renal Disease|Dialysis Dependent Chronic Kidney Disease|Sarcopenia
Interventions: DIAGNOSTIC_TEST: Hand grip function testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Ovarian, Fallopian Tube, or Peritoneal Cancer (GLORIOSA)
Status: RECRUITING
Conditions: Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Cancer
Interventions: DRUG: Mirvetuximab soravtansine plus Bevacizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of INtravenous FERRic Carboxymaltose Onmortality and Cardiovascular Morbidity, and Quality of Life in Iron Deficient Patients With Recent Myocardial infarCTion
Status: RECRUITING
Conditions: Myocardial Infarction, Acute
Interventions: DRUG: Ferinject|DRUG: Sodium Chloride 0.9% Inj
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Famotidine for Levodopa-induced Dyskinesia in PD
Status: COMPLETED
Conditions: Dyskinesia
Interventions: DRUG: Famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TH-SC01 in the Treatment of Radiation-induced Rectal Injury
Status: RECRUITING
Conditions: Rectal Injury
Interventions: BIOLOGICAL: TH-SC01(Umbilical cord mesenchymal stem cells)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Subcutaneous Abatacept in Rheumatoid Arthritis Assessing Inhibition of Structural Damage
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Subcutaneous Abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Levocarnitine and Vitamin B Complex in Treating PEG-Asparaginase or Inotuzumab Ozogamicin-Induced Hyperbilirubinemia in Patients With Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Hyperbilirubinemia
Interventions: DIETARY_SUPPLEMENT: Levocarnitine|DRUG: Vitamin B Complex
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vitamin A Palmitate Supplementation in Patients With Reticular Pseudodrusen (RPD) and Delayed Dark Adaptation
Status: COMPLETED
Conditions: Reticular Pseudodrusen (RPD)|Age-Related Macular Degeneration
Interventions: DRUG: Vitamin A Palmitate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Community Acquired Pneumonia in Older Adults
Status: COMPLETED
Conditions: Pneumonia|Aspiration Pneumonia
Interventions: DIAGNOSTIC_TEST: Videofluoroscopic Swallowing Study|DIAGNOSTIC_TEST: Nuclear medicine pulmonary aspiration study|DIAGNOSTIC_TEST: TOR-BSST and 3 oz Water Swallow|DIAGNOSTIC_TEST: Sputum Culture|DIAGNOSTIC_TEST: MeMed BV®|DIAGNOSTIC_TEST: Lung Ultrasound|DIAGNOSTIC_TEST: Respiratory Function Tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Anthracycline-based Chemotherapy on Peripheral Vascular Function
Status: COMPLETED
Conditions: Breast Cancer|Lymphoma|Chemotherapy Effect
Interventions: OTHER: Arterial blood pressure|OTHER: Vascular Ultrasound|OTHER: Venous blood sample|OTHER: Skin microcirculatory blood flow
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Role of Parecoxib Sodium for Postoperative Pain Management in Open Hepatectomy
Status: UNKNOWN
Conditions: Hepatic Hemangioma Located in the Right Liver|Laparotomy Surgery
Interventions: DRUG: Parecoxib Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Cell Suspension Grafting Using ReCell in Vitiligo and Piebaldism Patients
Status: UNKNOWN
Conditions: Piebaldism|Segmental Vitiligo
Interventions: PROCEDURE: ReCell epidermal cell suspension grafting|PROCEDURE: CO2 laser abrasion + UV-therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 16-Week Study of Pirenzepine or Placebo to Treat HIV-Associated Distal Sensory Polyneuropathy in Patients With HIV
Status: COMPLETED
Conditions: HIV Associated Polyneuropathy
Interventions: DRUG: WST-057|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancement of Circadian Rhythms in ICU Patients Through Light Intervention
Status: NOT_YET_RECRUITING
Conditions: Circadian Dysrhythmia
Interventions: DEVICE: Dynamic Light Therapy Device, LSA-1|DEVICE: Dynamic Light Therapy Device, LSA-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Topical Ophthalmic Steroids in a Modified Conjunctival Allergen Challenge (CAC) Model
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Prednisolone Acetate 1%|DRUG: Prednisolone Acetate 0.12%|DRUG: Loteprednol Etabonate 0.2%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hypoxia-altitude Testing to Predict Altitude Related Adverse Health Effects in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Hypoxia Altitude Simulation Test|High Altitude
Interventions: OTHER: hypoxia altitude simulation test (HAST) at 760m|PROCEDURE: High Altitude (3100m)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Internet-Based Interventions for Bipolar Disorder
Status: UNKNOWN
Conditions: Bipolar Disorder
Interventions: BEHAVIORAL: Moderated Discussion Board|BEHAVIORAL: Psychoeducation|BEHAVIORAL: Interactive Psychosocial Tools
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using A Novel Classification System in Intravenous GCs Therapy of TAO: A Multi-central, Randomized, Open, Superior Trial
Status: UNKNOWN
Conditions: Thyroid Associated Ophthalmopathy
Interventions: DRUG: Glucocorticoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Intervention in Orthopedic Trauma Patients
Status: RECRUITING
Conditions: Pain|Anxiety
Interventions: BEHAVIORAL: Preoperative mindfulness|BEHAVIORAL: Postoperative mindfulness|BEHAVIORAL: Mind wandering
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT