pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Tubeless NOSES Versus Laparoscopic Radical Resection for Rectosigmoid Cancers
Status: RECRUITING
Conditions: Tubeless NOSES|Traditional Laparoscopic Radical Resection|Rectosigmoid Cancers
Interventions: PROCEDURE: Tubeless NOSES|PROCEDURE: traditional laparoscopic radical resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Proprioceptive Neuromuscular Facilitation Training
Status: UNKNOWN
Conditions: Low Back Pain|Disability Physical
Interventions: OTHER: Proprioceptive Neuromuscular Facilitation Training|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Injectable Platelet-rich Fibrin on the En Masse Retraction of Maxillary Anterior Teeth
Status: RECRUITING
Conditions: Platelet-rich Fibrin
Interventions: BIOLOGICAL: injectable platelet rich fibrin(i-prf)|DRUG: Sham Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Performance and Usability of BALT Medical Devices: The EVIDENCE Post Marketing Clinical Follow-up Platform
Status: RECRUITING
Conditions: Intracranial Aneurysm|Brain Arterial Disease|Acute Ischemic Stroke|Peripheral Vascular Diseases|AVM - Cerebral Arteriovenous Malformation|AVM
Interventions: DEVICE: BALT medical devices
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Benefit of Rigourous AV Delay Optimization in Patients With a Dual Chamber Pacemaker
Status: COMPLETED
Conditions: Quality of Life|Pacemaker Ddd Permanent|Atrial Dysfunction
Interventions: DEVICE: AV optimization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of MIN-101 and Its Metabolites in Healthy Subjects to Compare MIN-101 in Poor and Extensive Metabolizers
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: MIN-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Compare the Efficacy and Safety of Beta-Glucan as Add-On to Statin in Subjects With Hyperlipidemia.
Status: COMPLETED
Conditions: Hyperlipidemias
Interventions: DRUG: CP105F|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mitochondria Oxidative Stress and Vascular Health Study
Status: RECRUITING
Conditions: Cardiovascular Diseases|Hypertension|Racism|Vascular Diseases
Interventions: DIETARY_SUPPLEMENT: MitoQ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Evaluation of Bepreve on the Measurement of Wheal and Flare Response From Histamine Skin Prick Testing
Status: COMPLETED
Conditions: Histamine Responsive Allergy Patients
Interventions: DRUG: Bepreve|DRUG: Refresh Tears
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Pirfenidone for the Reduction of Metabolic, Inflammatory and Fibrogenic Activity in Complicated Silicosis
Status: UNKNOWN
Conditions: Silicosis|Progressive Massive Fibrosis|Complicated Silicosis
Interventions: DRUG: Pirfenidone Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Rate of Anterior Segment Retraction Using Two Types of Mechanics
Status: COMPLETED
Conditions: Bimaxillary Protrusion
Interventions: OTHER: Friction Mechanics|OTHER: Frictionless Mechanics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Triple Therapy With Tegoprazan in H. Pylori Positive Patients
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Tegoprazan/Amoxicillin/Clarithromycin|DRUG: Lansoprazole/Amoxicillin/Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Assess the Safety and Activity of SRT501 Alone or in Combination With Bortezomib in Patients With Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: 5.0g SRT501|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study on Therapeutic Double-plasmid Hepatitis B Virus (HBV) DNA Vaccine in Patients With HBeAg-positive Chronic Hepatitis B
Status: UNKNOWN
Conditions: Chronic Hepatitis B Patients With HBeAg-positive
Interventions: BIOLOGICAL: HBV DNA Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation in a Multimodal Structured Curriculum of Laparoscopic Surgery
Status: COMPLETED
Conditions: Medical Education|Laparoscopic Surgery
Interventions: OTHER: Surgical Training Intervention|OTHER: Positive Control|OTHER: Negative Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study on Safety and Efficacy of Two Doses of Topiramate as Monotherapy in the Treatment of Newly Diagnosed or Recurrent Epilepsy
Status: COMPLETED
Conditions: Epilepsy|Seizures|Epilepsies, Partial|Epilepsy, Generalized|Epilepsy, Tonic-Clonic
Interventions: DRUG: topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Optical Coherence Tomography to Improve Outcome for Coronary Revascularisation Using Bioresorbable Vascular Scaffolds
Status: TERMINATED
Conditions: Coronary Occlusion
Interventions: OTHER: OCT-guided PCI|OTHER: Angiography-guided PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Clinical Referral to Activity Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Physical Inactivity|Cardiovascular Risk Factor|Obesity|Blood Pressure|PreDiabetes
Interventions: BEHAVIORAL: ActiveGOALSv2|BEHAVIORAL: PAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: IMM2902 in Patients With Advanced Solid Tumors Expressing HER2
Status: RECRUITING
Conditions: Advanced Solid Tumor|Advanced Lung Cancer|Advanced Gastric Carcinoma|Advanced Cholangiocarcinoma
Interventions: DRUG: IMM2902
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravesical Epirubicin Plus BCG to Prevent the Recurrence of Transitional Cell Carcinoma of Bladder
Status: COMPLETED
Conditions: Bladder Neoplasms
Interventions: DRUG: Trement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Investigate Effects of Repeated Administration of Itraconazole on Pharmacokinetics of JNJ-42847922 in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-42847922|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Novel Hyaluronic Acid Based Gel for Volume Deficiency in the Mid-face (FaceHyal)
Status: RECRUITING
Conditions: Volume Deficiency in the Mid-Face|Aging|Aesthetics
Interventions: DEVICE: IPN-21-SENSE|DEVICE: IPN-21-SENSE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Leakage With Nasal Prongs and Nasal Mask Interface in Newborns Receiving CPAP Treatment
Status: COMPLETED
Conditions: Respiration; Insufficient or Poor, Newborn|Infant,Premature
Interventions: DEVICE: Nasal mask interface|DEVICE: Nasal prongs interface
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Erlotinib After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: bevacizumab|DRUG: erlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Mitomycin C and Nasal Splint to Treat Nasal Synechiae
Status: COMPLETED
Conditions: Nasal Synechiae|Adhesions of Nasal Cavity|Nasal Adhesions|Tissue Adhesions
Interventions: DRUG: Mitomycin C|DEVICE: Teflon nasal septal splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Methods for Implementing Measurement-Based Care for Youth in Low-resource Environments
Status: RECRUITING
Conditions: Mental Health
Interventions: BEHAVIORAL: IMPACT Methods to Identify and Prioritize Determinants (Challenge I), Challenge and Match strategies to Prioritized Determinants (Challenge II)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Open-label, Phase 2trial of Sotorasib in KRAS G12C-mutant Non-small-cell Lung Cancer(NSCLC) Patients and a Translational Study to Find Acquired Resistance Mechanism to Sotorasib
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: sotorasib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Everolimus on the Pharmacokinetics of Tacrolimus in Renal Transplant Patients
Status: COMPLETED
Conditions: Drug Interaction Potentiation
Interventions: DRUG: Everolimus|DRUG: Mycophenolate mofetil|DRUG: Tacrolimus|DRUG: Methylprednisolone|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Video Discharge Instructions (VDI) as Adjuncts to Written Discharge Instructions in the Emergency Department
Status: COMPLETED
Conditions: Urinary Tract Infection|Head Injury|Laceration
Interventions: OTHER: Video discharge instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Sodium Hyaluronate In Relieving Nasal Symptoms Of Children With Seasonal Allergic Rhinitis
Status: UNKNOWN
Conditions: Seasonal Allergic Rhinitis
Interventions: OTHER: "Total nasal symptom score" (TNSS)|BEHAVIORAL: Paediatric Rhinoconjunctivitis Quality of Life Questionnaire" (PRQLQ)|DIAGNOSTIC_TEST: Nasal cytology|DIAGNOSTIC_TEST: anterior rhinomanometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Emotional Freedom Technique and Diaphragmatic Breathing on Post Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Emotional Freedom Techniques (EFT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ABSORB Clinical Investigation, Cohort B
Status: COMPLETED
Conditions: Coronary Disease|Coronary Artery Disease|Coronary Restenosis
Interventions: DEVICE: Bioabsorbable Everolimus Eluting Coronary Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of the Combination of Intravenous Alvespimycin (KOS-1022), Trastuzumab With or Without Paclitaxel in Patients With Advanced Solid Tumor Malignancies or Her2 Positive Metastatic Breast Cancer Who Have Previously Failed Trastuzumab Therapy
Status: COMPLETED
Conditions: Solid Tumor|Breast Cancer
Interventions: DRUG: Alvespimycin|DRUG: Trastuzumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Efficacy of the Addition of Omarigliptin (MK-3102) to Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin Therapy (MK-3102-024)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Omarigliptin|DRUG: Matching placebo to omarigliptin|DRUG: Glimepiride|DRUG: Matching placebo to glimepiride|DRUG: Insulin glargine|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Nitazoxanide in the Treatment of Chronic Hepatitis C Virus (HCV)
Status: COMPLETED
Conditions: Chronic Hepatitis c
Interventions: DRUG: Pegylated interferon alfa-2a|DRUG: Nitazoxanide|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Senolytic Agent Improve the Benefit of Platelet-Rich Plasma and Losartan
Status: ACTIVE_NOT_RECRUITING
Conditions: Femoroacetabular Impingement
Interventions: DRUG: Fisetin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Contraceptive Vaginal Rings on Primary Dysmenorrhea (P08257/MK-8175A/MK-8342B-057)
Status: COMPLETED
Conditions: Dysmenorrhea
Interventions: DRUG: Nomegestrol acetate contraceptive vaginal ring (NOMAC-CVR)|DRUG: Etonogestrel containing contraceptive vaginal ring (ENG-CVR)|DRUG: Placebo|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PET/CT Scanning for the Follow-up of Antibiotic Treatment of Infectious Osteoarthritis in the Diabetic Foot
Status: TERMINATED
Conditions: Diabetic Foot|Osteoarthritis
Interventions: PROCEDURE: Bone scintigraphy|PROCEDURE: Leukoscan|PROCEDURE: PET / CT|PROCEDURE: Bone biopsy|BIOLOGICAL: Bloodwork
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Genetic Determinants of Amitriptyline Efficiency for Pain Treatment - Part II
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: Amitriptyline|DRUG: Tolterodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Assess the Effect of Vildagliptin on Beta Cell Function in Drug Naive Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: vildagliptin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Topical 5-Fluorouracil Effervescent Powder in the Treatment of Vitiligo
Status: RECRUITING
Conditions: Vitiligo|Topical Fluorouracil|Effervescent Mixture
Interventions: DRUG: a new effervescent mixture 5-florouracil formula|DRUG: 5-Fluorouracil plain powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Micronutrient Supplementation (MMS) vs IFA Acceptability Crossover Trial
Status: NOT_YET_RECRUITING
Conditions: Pregnancy Related
Interventions: DIETARY_SUPPLEMENT: Iron Folic Acid Tablets with 60 mg of iron|DIETARY_SUPPLEMENT: Multiple Micronutrient Supplements with 60 mg of elemental iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Bioavailability of Metformin Between Medium Dose Linagliptin/Metformin Tablets and Medium Dose Glucophage Tablet Given With Linagliptin Tablet
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Metformin Single Tablet|DRUG: Linagliptin/Metformin Combo|DRUG: Linagliptin Single Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects Of Ciclesonide And Beclomethasone On Lens Opacification In Adult Subjects With Moderate To Severe Persistent Asthma
Status: COMPLETED
Conditions: Respiratory Tract Diseases|Respiratory Hypersensitivity|Asthma
Interventions: DRUG: ciclesonide (XRP1526)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NVT ALLEGRA TAVI System TF in Failing Surgical Aortic Bioprosthesis
Status: COMPLETED
Conditions: Transcatheter Aortic Valve Implantation
Interventions: DEVICE: Transcatheter Aortic Valve Implantation (TAVI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Superiority Effect of Orally Disintegrating Desmopressin Tablets to Placebo in Terms of Night Voids Reduction in Nocturia Adult Male Patients
Status: COMPLETED
Conditions: Nocturia
Interventions: DRUG: Desmopressin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Airtraq Versus Macintosh Laryngoscope for Endotracheal Intubation by First Year Resident
Status: UNKNOWN
Conditions: Intubation; Difficult or Failed|Intubation Complication
Interventions: DEVICE: Orotracheal intubation with either Macintosh laryngoscope versus Airtraq video laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Feasibility and Preliminary Efficacy of a Web-Based Self-Help Program for College Students
Status: COMPLETED
Conditions: Repetitive Negative Thinking
Interventions: BEHAVIORAL: RNT Focused Web- Based Self-Help Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Intervention Effects of rTMS on Children With Autism Spectrum Disorder
Status: RECRUITING
Conditions: Autism
Interventions: DEVICE: Applied high amplitude repeated transcranial magnetic stimulation|DEVICE: Applied low amplitude repeated transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: "Salvage Use" of Recombinant Factor VIIa After Inadequate Haemostasis in Complex Cardiac Surgery
Status: UNKNOWN
Conditions: Myocardial Ischemia|Blood Coagulation Disorders|Coronary Artery Disease|Heart Valve Diseases
Interventions: DRUG: Recombinant Activated Factor VII
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study Using Brain Stimulation and Behavioral Therapy to Increase Extent of Resection in Low-Grade Gliomas
Status: NOT_YET_RECRUITING
Conditions: Glioma|Glioma Intracranial|Gliomas Benign|Brain Tumor|Brain Cancer|Motor Cortex; Lesion
Interventions: DEVICE: RNS System Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Flotetuzumab in Primary Induction Failure (PIF) or Early Relapse (ER) Acute Myeloid Leukemia (AML)
Status: TERMINATED
Conditions: AML
Interventions: BIOLOGICAL: Flotetuzumab 3 ng/kg/day, 4 days on and 3 days off|BIOLOGICAL: Flotetuzumab 10 ng/kg/day, 4 days on and 3 days off|BIOLOGICAL: Flotetuzumab 30 ng/kg/day, 4 days on and 3 days off|BIOLOGICAL: Flotetuzumab 100 ng/kg/day, 4 days on and 3 days off|BIOLOGICAL: Flotetuzumab 300 ng/kg/day, 4 days on 3 days off, after one-step lead-in dose|BIOLOGICAL: Flotetuzumab 500 ng/kg/day, 4 days on 3 days off, after one-step lead-in dose|BIOLOGICAL: Flotetuzumab 500 ng/kg/day, continuous infusion, after multi-step lead-in dose|BIOLOGICAL: Flotetuzumab 700 ng/kg/day, 4 days on 3 days off, after multi-step lead-in dose|BIOLOGICAL: Flotetuzumab 700 ng/kg/day, continuous infusion, after multi-step lead-in dose|DRUG: Ruxolitinib|BIOLOGICAL: Flotetuzumab 300 ng/kg/day, continuous infusion, after multi-step lead-in dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Alexandrite Laser and Topical Therapy vs Topical Therapy Alone for Treatment of Melasma
Status: COMPLETED
Conditions: Melasma
Interventions: OTHER: 755nm Alexandrite Laser and Lytera Skin Brightening System (Non-Hydroquinone Topical Therapy)|OTHER: Lytera Skin Brightening System (Non-hydroquinone topical therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Smartwatch SAMSUNG to Monitor Sleep Quality: an Observational Prospective Study - SleepEx2 Protocol
Status: COMPLETED
Conditions: Insomnia|Sleep Initiation and Maintenance Disorders|Health Status|Wearable Electronic Devices|Sleep
Interventions: DEVICE: Wears the smartwatch during the sleep time to capture sleep characteristics and answer questionaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Thiazolidinediones Or Sulphonylureas and Cardiovascular Accidents.Intervention Trial
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus|Cardiovascular Disease
Interventions: DRUG: add-on pioglitazone|DRUG: add-on sulphonylurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hair Testing to Assess Consumption of Illicit Psychotropic Agents and Alcohol by Patients Treated With High-dose Buprenorphine and Methadone. Search for a Pharmacogenetic Contribution to Low Efficacy of Substitution Medications
Status: UNKNOWN
Conditions: Substance Abuse
Interventions: OTHER: hair and saliva samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Feasibility Study of Post-hospitalization Interventions to Improve Physical Function in Older Adults
Status: COMPLETED
Conditions: Aging
Interventions: DRUG: Placebo|DIETARY_SUPPLEMENT: Nutritional Supplement|BEHAVIORAL: In-home exercise|DRUG: Testosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Role of Acetaldehyde in the Development of Oral Cancer
Status: RECRUITING
Conditions: Alcohol-Related Carcinoma|Fanconi Anemia|Oral Cavity Carcinoma
Interventions: DRUG: Alcohol|PROCEDURE: Biospecimen Collection|PROCEDURE: Breath Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Efficacy and Tolerability of Rizatriptan for Treatment of Acute Migraine (0462-087)
Status: COMPLETED
Conditions: Acute Migraine
Interventions: DRUG: rizatriptan|DRUG: Comparator: Placebo|DRUG: Comparator: Sumatriptan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Relapse Prevention Study of Pimavanserin in Dementia-related Psychosis
Status: COMPLETED
Conditions: Dementia-related Psychosis
Interventions: DRUG: Placebo|DRUG: Pimavanserin 34 mg|DRUG: Pimavanserin 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RV Systolic and Diastolic Function and Contractile Reserve Under Acute Exercise and in Response to Chronic Exercise-based Rehabilitation
Status: UNKNOWN
Conditions: Pulmonary Hypertension|Right Heart Failure|Heart Failure|Contractility|RV-arterial Coupling
Interventions: OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Axitinib Monotherapy With Early Dynamic Contrast Enhanced Ultrasound Monitoring in Chemorefractory Third Line Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Axitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Regional Lung Ventilation Imaging Using 3T MR Imaging With Ultrashort Echo Time (UTE) Pulse Sequences
Status: COMPLETED
Conditions: Magnetic Resonance Imaging
Interventions: OTHER: Lung MRI examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of GSK Biologicals' Seasonal Influenza Vaccine in Children
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Quadrivalent seasonal influenza vaccine GSK2282512A|BIOLOGICAL: Fluarix™ VB|BIOLOGICAL: Fluarix™ YB|BIOLOGICAL: Quadrivalent seasonal influenza vaccine GSK2282512A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Local Anesthetic Infusion Pump Versus DepoFoam Bupivacaine for Pain Management
Status: WITHDRAWN
Conditions: Pain
Interventions: DRUG: Exparel|DRUG: Marcaine|DRUG: Marcaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Attributes for Optimal Treatment Outcome in Irritable Bowel Syndrome.
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: BEHAVIORAL: Cognitive Behavior Therapy(CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Of Quadratus Lumborum II Block For Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Morbid Obesity|High BMI
Interventions: DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BM-MNCs for Lower Extremity Compartment Syndrome Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Compartment Syndrome Traumatic Lower Extremity
Interventions: BIOLOGICAL: Intramuscular administration of autologous BM-MNCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of XPF-001 to Treat Pain Following Wisdom Tooth Extraction
Status: COMPLETED
Conditions: Dental Pain
Interventions: DRUG: XPF-001|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LaserEn: SOLTIVE™ Thulium Laser Fiber En Bloc Resection of Bladder Tumors
Status: UNKNOWN
Conditions: Bladder Cancer|Surgery
Interventions: PROCEDURE: SOLTIVE™ Thulium Laser Fiber En Bloc Resection of Bladder Tumors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Restenosis Treatment With Rapamycin Eluting Stent or Paclitaxel Eluting Balloon Catheter (RESTENOZA)
Status: UNKNOWN
Conditions: In-Stent Restenosis
Interventions: DEVICE: Rapamycin eluting stent implantation|DEVICE: Paclitaxel eluting balloon catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SPI-1005 for Prevention and Treatment of Tobramycin Induced Ototoxicity
Status: COMPLETED
Conditions: Ototoxicity
Interventions: DRUG: Placebo|DRUG: SPI-1005 Ebselen 200mg Capsule x1|DRUG: SPI-1005 Ebselen 200mg Capsule x2|DRUG: SPI-1005 Ebselen 200mg Capsule x3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Imatinib and Imatinib/Pegylated Interferon in Chronic Myeloid Leukemia
Status: COMPLETED
Conditions: Health Care Quality|Health Care Evaluation
Interventions: DRUG: imatinib and pegylated interferon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Avastin Followed by Maintenance Treatment With Avastin +/- Tarceva
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: erlotinib (Tarceva)|DRUG: bevacizumab (Avastin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of PAP on ISSHL Comorbided With OSA
Status: RECRUITING
Conditions: Sudden Hearing Loss|Obstructive Sleep Apnea
Interventions: DEVICE: non-invasive positive airway pressure|DRUG: Methylprednisolone Hemisuccinate|DRUG: Ginaton
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Dual Anti-HER2 Therapy in Patients With Small, Node-negative, HER2-positive Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: HER2-positive Breast Cancer
Interventions: DRUG: Pyrotinib|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Clinical Study Evaluating the Possible Efficacy of Duloxetine, Gabapentin and Lacosamide on Oxaliplatin-Induced Peripheral Neuropathy in Cancer Patients
Status: RECRUITING
Conditions: Oncology
Interventions: OTHER: Duloxetine|OTHER: Gabapentin|OTHER: Lacosamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Comparative Safety and Effectiveness of Dabigatran, Versus Rivaroxaban, and Apixaban Utilized in the Department of Defense Non-Valvular Atrial Fibrillation Patient Population: A Retrospective Database Analysis
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Dabigatran vs. Rivaroxaban|DRUG: Dabigatran vs. Apixaban
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vosaroxin for Intermediate 2 or High-risk MDS After Failure With Hypomethylating Agent-based Therapy
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: Vosaroxin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Axitinib With or Without Anti-OX40 Antibody PF-04518600 in Treating Patients With Metastatic Kidney Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Clear Cell Renal Cell Carcinoma|Metastatic Renal Cell Cancer|Recurrent Renal Cell Carcinoma|Stage IV Renal Cell Cancer
Interventions: BIOLOGICAL: Anti-OX40 Antibody PF-04518600|DRUG: Axitinib|OTHER: Laboratory Biomarker Analysis|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Torrent Pharmaceutical Ltd.'s Montelukast Sodium 10mg Tablet Under Fasted Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Torrent's Montelukast Sodium Tablets 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac and Cerebral Hemodynamics With Umbilical Cord Milking Compared With Early Cord Clamping
Status: COMPLETED
Conditions: Birth Asphyxia With Neurologic Involvement
Interventions: PROCEDURE: Umbilical Cord Milking|PROCEDURE: Early Cord Clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy, Safety and Pharmacokinetics Study of CPL500036 (PDE10A Inhibitor) in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: CPL500036 - low dose|DRUG: CPL500036 - high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does Endurance Improve With the Use of Passy-Muir Valve for Patients With Tracheostomy?
Status: ENROLLING_BY_INVITATION
Conditions: PMV|Exercise Endurance|Tracheostomy
Interventions: OTHER: Open Tracheostomy|DEVICE: PMV in place
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Tamoxifen With or Without Vorinostat for the Treatment of Estrogen Receptor Positive Breast Cancer
Status: TERMINATED
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Prognostic Stage IV Breast Cancer AJCC v8
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Tamoxifen|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole-body Electromyostimulation Versus Conventional Low-volume Strength Training in Overweight Individuals
Status: UNKNOWN
Conditions: Overweight and Obesity|Metabolic Syndrome
Interventions: OTHER: Control|OTHER: Standard Strength Training|OTHER: Low-volume Strength Training|OTHER: Whole-Body Electromyostimulation (WB-EMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ph3 Multicenter, 3wk RDBPC Efficacy, Safety & PK Study of Evening Dosed MPH HCl ER Capsules (HLD200) in Children 4-5 Yr With ADHD
Status: NOT_YET_RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: HLD200 methylphenidate hydrochloride capsules|DRUG: Placebo HLD200 capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bilateral Thoracoscopic Splanchnicectomy for Pain Relief in Patients With Unresectable Pancreatic Cancer
Status: WITHDRAWN
Conditions: Unresectable Pancreatic Cancer
Interventions: PROCEDURE: Bilateral Thoracoscopic Splanchnicectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combined Use of Raltitrexed and S-1 as Treatment for Patients With Metastasizing Colorectal Cancer
Status: UNKNOWN
Conditions: Metastatic Colon Cancer
Interventions: DRUG: Raltitrexed and S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PErsonalized Genomics for Prenatal Abnormalities Screening USing Maternal Blood
Status: ACTIVE_NOT_RECRUITING
Conditions: Prenatal Disorder|Aneuploidy
Interventions: DIAGNOSTIC_TEST: Traditional integrated prenatal screening|DIAGNOSTIC_TEST: Second-tier Non-invasive prenatal screening (NIPS)|DIAGNOSTIC_TEST: First-tier Non-invasive prenatal screening (NIPS)|DIAGNOSTIC_TEST: Invasive prenatal testing for fetal aneuploidy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: COPD AND ASSESSMENT OF RADIOLABELED AEROSOL DURING NONINVASIVE VENTILATION
Status: COMPLETED
Conditions: COPD
Interventions: OTHER: Noninvasive ventilation|DEVICE: Jet Nebulizer|DEVICE: Vibrating Mesh Nebulizer (VMN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Types of Resistant Starch
Status: COMPLETED
Conditions: Postprandial Hyperglycemia
Interventions: DIETARY_SUPPLEMENT: Resistant Starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Foam Roller Versus KT Tape on Delayed Onset Muscle Soreness
Status: ACTIVE_NOT_RECRUITING
Conditions: Delayed Onset Muscle Soreness
Interventions: OTHER: Foam Rolling|OTHER: Kinesio Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Effectiveness of Different Lifestyle Interventions for Health and Wellbeing
Status: COMPLETED
Conditions: Metabolic Syndrome Risk Factors|Overweight|Psychological Stress
Interventions: BEHAVIORAL: Wellbeing intervention (ACT)|BEHAVIORAL: Wellbeing intervention (Internet)|BEHAVIORAL: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: The Effectiveness of Clear Aligner and Traditional Fixed Appliances in Achieving Good Occlusion in Complex Orthodontic Cases
Status: COMPLETED
Conditions: Crowding, Tooth
Interventions: DEVICE: Clear aligners|DEVICE: Fixed appliances
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Safety and Efficacy of CAR-T/CAR-NK Cells in the Treatment of Recurrent Refractory or Unresectable Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Safety and Efficacy of Cellular Drugs, Objective Response Rate of Subjects, Etc
Interventions: BIOLOGICAL: CAR-T/CAR-NK cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Repeated Administrations of NurOwn® in ALS Patients
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: BIOLOGICAL: NurOwn® (MSC-NTF cells)|OTHER: Placebo|OTHER: Bone Marrow aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Trial of the Novel Tuberculosis Vaccine Candidate, H107e/CAF®10b
Status: RECRUITING
Conditions: Healthy
Interventions: BIOLOGICAL: H107e|BIOLOGICAL: CAF®10b|BIOLOGICAL: H107e/CAF®10b - low adjuvant dose|BIOLOGICAL: H107e/CAF®10b - full adjuvant dose|BIOLOGICAL: Low dose intranasal H107e|BIOLOGICAL: Full dose intranasal H107e|BIOLOGICAL: H107e/CAF®10b|BIOLOGICAL: i.m. placebo|BIOLOGICAL: BCG|BIOLOGICAL: i.d. placebo|BIOLOGICAL: Intranasal H107e
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Concurrent Docetaxel Plus Cisplatin or Cisplatin Alone With IMRT in High Risk Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Cisplatin 2|DRUG: Docetaxel|DRUG: Cisplatin 1|RADIATION: Intensity-modulated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Asoprisnil in the Treatment of Uterine Fibroids.
Status: COMPLETED
Conditions: Fibroid Uterus|Leiomyoma|Menorrhagia|Metrorrhagia|Uterine Fibroids
Interventions: DRUG: Asoprisnil|DRUG: Asoprisnil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Toripalimab for dMMR/MSI-H Gastric Cancer
Status: RECRUITING
Conditions: Gastric or Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: PD-1 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Clinical Evaluation of 18F-LY3546117 in Tumor Imaging
Status: UNKNOWN
Conditions: Neoplasms|Neoplasms Malignant
Interventions: DRUG: 18F-LY3546117 Injection|PROCEDURE: PET Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Omegaven in Patients With Rheumatoid Arthritis (ORA-Trial)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Omegaven (10% fish-oil emulsion; Fresenius-Kabi)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study Of Milnacipran In Patients With Fibromyalgia: Effects On 24 Hour Ambulatory Blood Pressure Monitoring
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Milnacipran hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metronidazole vs Azithromycin in Periodontal Surgery for Patients Positive to Porphyromonas Gingivalis
Status: UNKNOWN
Conditions: Periodontitis|Surgery
Interventions: OTHER: Azithromycin|OTHER: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The UBC Long-distance Triathlon Adaptation Study
Status: RECRUITING
Conditions: Healthy Participants
Interventions: OTHER: Individualized, periodized endurance training for ultra-endurance triathlon.|OTHER: Time-Aligned Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neoadjuvant Radiation Therapy and Capecitabine in Treating Patients With Stage III or Stage IV Colorectal Adenocarcinoma
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: capecitabine|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ZEN003694 in Combination With Enzalutamide in Patients With Metastatic Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Castration-Resistant Prostate Cancer
Interventions: DRUG: ZEN003694|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Uplifting Equitable Park Use and Promoting Physical Activity Among African American Families in Minnesota: A Culturally-Responsive, Community-Engaged Approach
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: BEHAVIORAL: NatureUplift|BEHAVIORAL: NatureUplift+Active
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Supplemental Intake of Omega-3 Polyunsaturated Fatty Acids on the Rate and Complexity of Spontaneously Occurring Ventricular and Supraventricular Arrhythmias in Patients With Implantable Cardioverter Defibrillator (ICD) - A Randomized Clinical Trial
Status: UNKNOWN
Conditions: Coronary Artery Disease|Arrhythmia
Interventions: DRUG: Eicosapentanoic acid (EPA) and Docosahexanoic acid (DHA).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Melphalan Flufenamide (Melflufen) and Dexamethasone for Patients With Immunoglobulin Light Chain (AL) Amyloidosis
Status: TERMINATED
Conditions: AL Amyloidosis
Interventions: DRUG: Melphalan-Flufenamide (Melflufen)|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 0.25% Desoximetasone Cream (Topoxy®) in the Treatment of Scalp Psoriasis
Status: UNKNOWN
Conditions: Scalp Psoriasis
Interventions: DRUG: 0.25% Desoximetasone cream (Topoxy®)|DRUG: 0.25% Desoximetasone cream (Topicorte®)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The IMPACT Study - Identification of Men With a Genetic Predisposition to ProstAte Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer|BRCA Mutation|Mismatch Repair Gene Mutation|Genetic Predisposition to Disease
Interventions: DIAGNOSTIC_TEST: PSA test|PROCEDURE: Prostate Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Cilostazol Endothelial Progenitor Cells and Collateral Formation in Peripheral Occlusive Artery Disease (PAOD)
Status: COMPLETED
Conditions: Peripheral Arterial Diseases
Interventions: DRUG: Cilostazol|DRUG: Dummy Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT