pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Manual Therapy, Kinesiotape and Strength Training in Soccer Players With Recurrent Ankle Sprains
Status: COMPLETED
Conditions: Ankle Sprains
Interventions: OTHER: Experimental|OTHER: Manual therapy group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Increasing Knowledge of Alcohol as a Risk Factor for Breast Cancer Among Women Attending Breast Screening Services
Status: COMPLETED
Conditions: Health Knowledge, Attitudes, Practice|Alcohol Consumption
Interventions: BEHAVIORAL: alcohol brief intervention|BEHAVIORAL: lifestyle health promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of IBI353 (Orismilast) in Chinese Healthy Adults
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: IBI353 (Orismilast)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Indirect Pulp Capping With Biodentine and TheraCal LC in Permanent Mature Molars
Status: UNKNOWN
Conditions: Deep Carious Lesions|Reversible Pulpitis|Indirect Pulp Capping
Interventions: DRUG: Indirect pulp capping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Dose-ranging Study of Oral RV3-BB Rotavirus Vaccine
Status: COMPLETED
Conditions: Rotavirus Infections
Interventions: BIOLOGICAL: RV3-BB|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial for 'Shen Qu Xiao Shi' Oral Liquid in the Treatments of Children's Functional Dyspepsia
Status: COMPLETED
Conditions: Dyspepsia
Interventions: DRUG: Shenqu Xiaoshi oral liquid|DRUG: Domperidone suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eplerenone, ACE Inhibition and Albuminuria
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: eplerenone|DRUG: fosinopril|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gradual Initiation of Sulfamethoxazole/Trimethoprim as Primary Pneumocystis Carinii Pneumonia Prophylaxis
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Sulfamethoxazole-Trimethoprim
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: IV Acetaminophen for Postoperative Analgesia
Status: TERMINATED
Conditions: Postoperative Pain|Postoperative Nausea|Postoperative Vomiting
Interventions: DRUG: IV Acetaminophen|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Thoracic Epidural Anesthesia With Different Block Level on Propofol Induction
Status: COMPLETED
Conditions: Target Controlled Infusion (TCI)|Thoracic Epidural Anesthesia|Block Level|Gastrointestinal Surgery
Interventions: DRUG: 1% lidocaine|DRUG: 2% lidocaine|DRUG: 0.9% normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Leflunomide in Treating Patients With Steroid Dependent Chronic Graft Versus Host Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Graft Versus Host Disease|Steroid Refractory Graft Versus Host Disease
Interventions: DRUG: Leflunomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calcinosis Reduction by Pyrophosphate in SSC
Status: NOT_YET_RECRUITING
Conditions: Systemic Sclerosis|Scleroderma
Interventions: DIETARY_SUPPLEMENT: Pyrophosphate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aesthetic Effect of Steri-Strip Orientation on Healing and Scar Appearance in Breast Surgery
Status: COMPLETED
Conditions: Scar|Breast Neoplasms|Breast Diseases|Surgical Wound
Interventions: DEVICE: Steri-strip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Biological Effects of Ultrasound Insonification of the Spleen
Status: UNKNOWN
Conditions: Healthy Volunteer
Interventions: DEVICE: Ultrasound|DEVICE: Sham Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Alternative Booster Vaccine Against Meningitis and Ear Infections
Status: COMPLETED
Conditions: Invasive Streptococcus Pneumoniae Disease
Interventions: BIOLOGICAL: 13-valent pneumococcal conjugate vaccine|BIOLOGICAL: 10-valent pneumococcal conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Test the Benefit and Safety of GM-CT-01 in Combination With 5-FU to Treat Bile Duct and Gall Bladder Cancer
Status: WITHDRAWN
Conditions: Cancer of the Bile Duct|Gallbladder Cancer
Interventions: DRUG: GM-CT-01|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Dexmedetomidine Versus Fentanyl With Bupivacaine in Children Undergoing Major Abdominal Cancer Surgery
Status: UNKNOWN
Conditions: Intrathecal Dexmedetomidine|Pediatric Cancer Surgery
Interventions: DRUG: Bupivacaine|DRUG: Fentanyl|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diffusion Weighted Magnetic Resonance in Imaging Younger Patients With Newly Diagnosed Bone or Soft Tissue Sarcomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcoma, Bone|Sarcoma, Soft Tissue|Osteosarcoma|Sarcoma, Ewing|Rhabdomyosarcoma|Non-rhabdomyosarcoma Soft-tissue Sarcoma
Interventions: PROCEDURE: Diffusion Weighted Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacodynamics, Safety and Pharmacokinetics After Oral Administration of BIBR 1048 MS in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBR 1048 MS dose 1|DRUG: BIBR 1048 MS dose 2|DRUG: BIBR 1048 MS dose 3|DRUG: BIBR 1048 MS dose 4|DRUG: BIBR 1048 MS dose 5|DRUG: Placebo to BIBR 1048 MS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between Neuropsychological Testing and MRI, PET and COBRE - Project 1: AIM 2 (GE-180)
Status: TERMINATED
Conditions: Alzheimer Disease|Parkinson Disease|Inflammation
Interventions: DRUG: GE180 PET Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CED With Irinotecan Liposome Injection Using Real Time Imaging in Children With Diffuse Intrinsic Pontine Glioma (DIPG) (PNOC 009)
Status: COMPLETED
Conditions: Diffuse Intrinsic Pontine Glioma
Interventions: DRUG: Convection Enhanced Delivery (CED) of Nanoliposomal irinotecan (nal-IRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Adaptive Deep Brain Stimulation for Obsessive-Compulsive Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Summit RC+S System with ECoG Paddles|OTHER: One Month Blinded Discontinuation Period:
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: School Adolescent Mood Project: Efficacy of IPT-AST in Schools
Status: ACTIVE_NOT_RECRUITING
Conditions: Depressive Symptoms
Interventions: BEHAVIORAL: Interpersonal Psychotherapy - Adolescent Skills Training|BEHAVIORAL: Services as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of SGLT2i on Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients
Status: UNKNOWN
Conditions: Diabetic Retinopathy
Interventions: DRUG: Dapagliflozin 10mg Tab plus another oral hypoglycemic agent|DRUG: Two oral hypoglycemic agents other than dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Gold Nanocrystals
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buprenorphine Maintenance for Cocaine Abusing Opioid Addicts - 1
Status: COMPLETED
Conditions: Cocaine-Related Disorders|Opioid-Related Disorders|Substance-Related Disorders
Interventions: DRUG: Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Topical Clobetasol for the Treatment of Toxic Epidermal Necrolysis
Status: WITHDRAWN
Conditions: Toxic Epidermal Necrolysis
Interventions: DRUG: Clobetasol 0.05% ointment|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eosinophilic Esophagitis Intervention Trial-1 Food vs. 4 Food Elimination Diet Followed by Swallowed Glucocorticoids
Status: COMPLETED
Conditions: Eosinophilic Esophagitis|Eosinophilic Gastrointestinal Disorders (EGIDs)
Interventions: OTHER: 1 Food Elimination Diet|OTHER: 4 Food Elimination Diet|OTHER: 4 Food Elimination Diet (post 1FED failure)|DRUG: Fluticasone Propionate, 800 mcg twice daily (post 4FED failure)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Modified Lee White Clotting Time Against Twenty Minute Whole Blood Clotting Test in Snakebite Victims
Status: COMPLETED
Conditions: Coagulation Defect|Snake Bites
Interventions: DIAGNOSTIC_TEST: 20'Whole Blood ClottingTest (WBCT)|DIAGNOSTIC_TEST: Modified Lee and White (MLW) Method Clotting Time
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MPP Narrow QRS:Pilot Study on Multipoint Pacing in Patients With QRS Beetwen 100 and 130 Msec
Status: UNKNOWN
Conditions: Heart Failure
Interventions: DEVICE: MultiPoint Pacing ON|DEVICE: Implantable cardioverter-defibrillator (ICD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Adding L-BAIBA to Exercising Adult Overweight and Obese Men and Women
Status: TERMINATED
Conditions: Obesity|Weight Loss|Weight, Body|Cardiometabolic Syndrome
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Monoclonal Antibody Therapy in Treating Patients With Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|PROCEDURE: radionuclide imaging|RADIATION: iodine I 131 monoclonal antibody F19
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: COVID-19 Anosmia Study
Status: COMPLETED
Conditions: Anosmia|Covid19
Interventions: DRUG: Omega-3 Fatty Acid Supplement|DRUG: Placebo/Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Web-based Education Provided According to the Health Promotion Model on Self - Management in Epilepsy Patients
Status: NOT_YET_RECRUITING
Conditions: Epilepsy
Interventions: OTHER: Education|OTHER: CONTROL GROUP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Secukinumab Treatment in Patients With Plaque Psoriasis and Coexisting Non-alcoholic Fatty Liver Disease (NAFLD)
Status: TERMINATED
Conditions: Plaque Psoriasis|Non-alcoholic Fatty Liver Disease
Interventions: BIOLOGICAL: Investigational Arm - secukinumab|BIOLOGICAL: Control Arm - placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Telemonitoring for IBD Goodness Examination in Russia
Status: ENROLLING_BY_INVITATION
Conditions: Inflammatory Bowel Diseases|Crohn Disease|Ulcerative Colitis
Interventions: OTHER: Telemonitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Everolimus and Letrozole as Preoperative Therapy of Primary Breast Cancer in Post-menopausal Women
Status: COMPLETED
Conditions: Breast Neoplasm
Interventions: DRUG: RAD001, Letrozole 2.5mg|DRUG: Letrozole 2.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Combined Liver and Right Lung Resection for Colorectal Metastases by Means of J-shaped Thoracophrenolaparotomy
Status: COMPLETED
Conditions: Colon Cancer Liver Metastasis|Multiple Pulmonary Nodules
Interventions: PROCEDURE: Surgery of liver and lung
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rapid Hepatitis C Elimination Trial- A Pilot Study of Daclatasvir/Asunaprevir/BMS-791325 With or Without Ribavirin To Treat Hepatitis C Virus
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: DCV/ASV/BMS-791325|DRUG: DCV/ASV/BMS-791325 + RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tandem Peripheral Blood Stem Cell (PBSC) Rescue for High Risk Solid Tumors
Status: UNKNOWN
Conditions: Ewing's Sarcoma|Soft Tissue Sarcoma|Hepatoblastoma|Hodgkin's Disease|Germ Cell Tumor
Interventions: DRUG: High-Dose Chemotherapy with Tandem PBSC Rescue.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Electrical Nerve Stimulation for Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Percutaneous Electrical Nerve Stimulation|PROCEDURE: Endoscopic surgery of the carpal tunnel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determination of Cannabinoid and Cannabinoid Metabolite Levels in Healthy Volunteers
Status: WITHDRAWN
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Happy Lane Hemp Extract/CBD soft gels (25 mg/capsule)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Glycemic Response to Three Oral Nutrition Supplements in Persons With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes
Interventions: OTHER: Boost Glucose Control (A)|OTHER: Boost Glucose Control (B)|OTHER: Boost Original
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Open Label Extension Study for Subjects That Complete Study MP-101-CL-001
Status: WITHDRAWN
Conditions: Short Bowel Syndrome|Short Gut Syndrome|SBS|Short Gut
Interventions: DRUG: 0.6 mL, MP-101 (10 mg/mL, Opium Tincture (OT)), USP (Deodorized)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of EUS-Guided Liver Biopsy With Percutaneous Liver Biopsy
Status: WITHDRAWN
Conditions: Fibrosis
Interventions: PROCEDURE: Endoscopic ultrasound-guided liver biopsy|PROCEDURE: Percutaneous liver biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Mediterranean Diet as an add-on Therapy for Induction of Remission in Patients With Active Crohn's Disease
Status: UNKNOWN
Conditions: Crohn's Disease
Interventions: BEHAVIORAL: Mediterranean diet|BEHAVIORAL: Low residue diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Nephure™, and the Reduction of Dietary Oxalate, in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Nephure Oxalate-reducing Enzyme|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Assisted Robotic vs Laparoscopic Sleeve Gastrectomy
Status: RECRUITING
Conditions: Post Operative Pain|Laparoscopic Sleeve Gastrectomy|Robotic Sleeve Gastrectomy|Obesity|Bariatric Surgery Candidate|Quality of Life
Interventions: PROCEDURE: Laparoscopic Sleeve Gastrectomy (LSG)|PROCEDURE: Robotic Sleeve Gastrectomy (RSG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of Suvorexant in Participants With Primary Insomnia - Study A (MK-4305-028)
Status: COMPLETED
Conditions: Primary Insomnia
Interventions: DRUG: Suvorexant High Dose (HD)|DRUG: Suvorexant Low Dose (LD)|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Low-level Laser Therapy (808nm) on Marker of Muscle Damage
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Low-level laser therapy (808nm) and exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Carbohydrate Counting Method With Mixed Meals
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: OTHER: Mixed meal 1|OTHER: Mixed meal 2|OTHER: Mixed meal 3|OTHER: Mixed meal 4|OTHER: Mixed meal 5|OTHER: Mixed meal 6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: High-dose Vitamin D Supplements in Older Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Vitamin D Deficiency|Cognitive Decline
Interventions: DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Energetic Resonance by Cutaneous Stimulation on Withdrawal Alcohol Symptoms.
Status: COMPLETED
Conditions: Alcohol Withdrawal Syndrome
Interventions: OTHER: Energetic Resonance by Cutaneous Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Diet on Mood, Cognition and Appetite
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: OTHER: High Fat Low Carbohydrate Diet|OTHER: Low fat High Carbohydrate Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy & Safety of Infliximab Monotherapy Vs Combination Therapy Vs AZA Monotherapy in Ulcerative Colitis (Part 1) Maintenance Vs Intermittent Therapy for Maintaining Remission (Part 2)(Study P04807)
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: BIOLOGICAL: Infliximab (IFX)|DRUG: Azathioprine (AZA)|DRUG: Placebo to Azathioprine|DRUG: Placebo infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Omega-3 Fatty Acids (Fish Oil) in Patients With Chronic Hepatitis C Infection
Status: WITHDRAWN
Conditions: Hepatitis C
Interventions: DIETARY_SUPPLEMENT: Omega-3 Fatty Acids|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Vibrations, Passive Motion and Thermotherapy for Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis|Knee Pain
Interventions: DEVICE: "Kineticure System" followed by sham|DEVICE: sham followed by "Kineticure System"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Tailored Bowel Preparation Strategy: A Randomized Controlled Study
Status: UNKNOWN
Conditions: Bowel Preparation|Colonoscopy
Interventions: DRUG: 2L Polyethylene Glycol (PEG)|DRUG: 4L Polyethylene Glycol (PEG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Arterial Function After Two Different Physical Exercise Intensities in Prehypertension
Status: ACTIVE_NOT_RECRUITING
Conditions: Prehypertension|Masked Hypertension
Interventions: BEHAVIORAL: Moderate intensity continuous training - session|BEHAVIORAL: High intensity interval training - session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized Double Blind, Placebo Controlled Balanced 4-Way Crossover Study To Assess The Efficacy Of Single Oral Doses
Status: COMPLETED
Conditions: Impotence
Interventions: DRUG: PF-00592379|DRUG: Sildenafil 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Recovery of Visual Acuity in People With Vestibular Deficits
Status: COMPLETED
Conditions: Vestibular Neuronitis|Vestibular Neuronitis, Bilateral|Vestibular Schwannoma
Interventions: OTHER: Control exercises|OTHER: gaze stabilization exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Study for Evaluating the Safety of MASCT-I in Advanced Soild Tumor
Status: UNKNOWN
Conditions: Advanced Gastric Cancer
Interventions: BIOLOGICAL: MASCT-I|DRUG: PD1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2a Study to Evaluate Suppression of Radiotherapy-induced Mucositis by TK112690
Status: ACTIVE_NOT_RECRUITING
Conditions: Mucositis
Interventions: DRUG: TK-112690|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Retinal Oxygenation and Retinal Vessel Diameters in Healthy Subjects and Patients With Diabetic Retinopathy or Retinal Vein Occlusion Between DVA and Oxymap
Status: COMPLETED
Conditions: Healthy Subjects|Diabetic Retinopathy|Retinal Vein Occlusion
Interventions: OTHER: Dynamic Vessel Analyzer|OTHER: Oxymap T1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical and Anti-inflammatory Effect of Curcumin Oral Gel as Adjuncts in Treatment of Periodontal Pocket
Status: UNKNOWN
Conditions: Chronic Periodontitis
Interventions: DRUG: curcumin Oral gel|PROCEDURE: subgingival scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of Color Correcting Lenses on Color Vision Deficiency
Status: COMPLETED
Conditions: Color Blindness|Color Vision Defects|Color Blindness, Green|Color Blindness, Red
Interventions: DEVICE: Experimental Group 1: Color Correcting Lenses|DEVICE: Placebo Group 1: Placebo Lenses|DEVICE: Placebo Group 1 Crosses over to become Experimental Group 2: Color Correcting Lenses|DEVICE: Experimental Group 1 Crosses over to become Placebo Group 2: Placebo Lenses|DEVICE: Color Correcting Lenses in Subjects with Normal Color Vision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Basket Trial of IDX-1197, a PARP Inhibitor, in Patients With HRR Mutated Solid Tumors (VASTUS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumors|Homologous Recombination Repair Gene Mutation|Homologous Recombination Deficiency
Interventions: DRUG: IDX-1197
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: in Vivo TICE (TransIntestinal Cholesterol Excretion)
Status: UNKNOWN
Conditions: Occlusion of Bile Duct With an External Bile Diversion.
Interventions: OTHER: Intravenous injection of deuterated cholesterol diluted in intralipid 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Transcranial Direct Current Stimulation for Cognitive Improvement in Parkinson's Patients (tDCS)
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: transcranial direct current stimulation|DEVICE: Sham (for transcranial direct current stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Continuous Versus Syncopated Dosing of CC-5013 for the Treatment of Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: CC-5013
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nasal Carbon Dioxide (CO2) in the Treatment of Mild Headache in People Who Experience Migraines
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Nasal CO2|DRUG: Inactive Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IRESSA Combined With Radiotherapy & Gemcitabine as First-Line Treatment in Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gefitinib|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prostatic Urethral Lift (PUL) Pre-/Post-Radiation Treatment for Prostate Cancer
Status: WITHDRAWN
Conditions: Benign Prostatic Hyperplasia (BPH)|Prostate Cancer
Interventions: DEVICE: Prostatic Urethral Lift (PUL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Wearable Vibration Therapy on Shoulder Functionality in Individuals Receiving Adjuvant Radiotherapy After Breast Cancer Surgery
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: MYOVOLT (MyovoltTM, Myovolt Limited, Christchurch, New Zealand ) wearable vibration therapy device|OTHER: Home based exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Orbit Study: A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Intrathecally Administered ION356 in Participants With Pelizaeus Merzbacher Disease (PMD)
Status: RECRUITING
Conditions: Pelizaeus-Merzbacher Disease
Interventions: DRUG: ION356
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Testofen Compared to Placebo on Long COVID Symptoms
Status: RECRUITING
Conditions: Long Covid19
Interventions: DRUG: Testofen|DRUG: Microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring Learning and Unlearning of Fear
Status: WITHDRAWN
Conditions: Healthy Individuals
Interventions: DRUG: d-Cycloserine|DRUG: Lactose pill|GENETIC: Saliva sample|OTHER: Functional neuroimaging (fMRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of MabThera/Rituxan (Rituximab) in Patients With Non-Bulky Follicular Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: rituximab [MabThera/Rituxan]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CTLA-4 and PD-1 Antibodies Expressing EGFR-CAR-T Cells for EGFR Positive Advanced Solid Tumor
Status: UNKNOWN
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: anti-CTLA-4/PD-1 expressing EGFR-CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Controlled Trial Comparing Water and Air Colonoscopy in a Community Based Setting
Status: COMPLETED
Conditions: Tubular Adenoma|Colon Cancer|Hyperplastic Polyp
Interventions: OTHER: Water Exchange Colonoscopy|OTHER: Air Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Assess the Safety, Tolerability and Pharmacokinetics (PK) of Multiple Ascending Doses of ASP7962 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers|Pharmacokinetics of ASP7962
Interventions: DRUG: ASP7962|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prevalence of Metabolic Syndrome in Obstructive Sleep Apnea (OSA) and Effect of Treatment With Continuous Positive Airway Pressure (Auto-CPAP) on Metabolic Syndrome
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Metabolic Syndrome
Interventions: DEVICE: AutoSet Spirit|DEVICE: Modified-AutoSet Spirit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COPD Aerosol Study Comparing the Efficacy of Nebulizers Versus Dry Powder Inhalers
Status: COMPLETED
Conditions: COPD Exacerbation
Interventions: DRUG: Formoterol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Delayed Educational Reminders in Acute Myocardial Infarction (MI)
Status: COMPLETED
Conditions: Acute Myocardial Infarction|STEMI
Interventions: BEHAVIORAL: Educational Reminder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Plantar Fasciitis, Operation or Conservative Treatment
Status: COMPLETED
Conditions: Plantar Fasciitis
Interventions: PROCEDURE: endoscopic surgery|DRUG: methylprednisolon|DRUG: lidokaine|BEHAVIORAL: Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drinkers' Intervention to Prevent Tuberculosis (DIPT Study)
Status: COMPLETED
Conditions: HIV/AIDS|Tuberculosis
Interventions: BEHAVIORAL: Incentives for negative EtG test|BEHAVIORAL: Incentives for positive IsoScreen test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Primary Stability of Immediate Implant Using Versah Versus Conventional Burs
Status: ACTIVE_NOT_RECRUITING
Conditions: Edentulous Alveolar Ridge
Interventions: PROCEDURE: Densah® burs|PROCEDURE: Conventional Burs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acute Diverticulitis and Advanced Colonic Neoplasia. When to Perform Colonoscopy (ADACOLON Study)
Status: COMPLETED
Conditions: Diverticulitis, Colonic|Colonic Neoplasms
Interventions: DIAGNOSTIC_TEST: Colonoscopy|DIAGNOSTIC_TEST: Fecal immunochemical and occult blood test|DIAGNOSTIC_TEST: Fecal calprotectin test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 1 Safety Study of Single and Repeated Doses of JSM6427 (Intravitreal Injection) to Treat AMD
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: JSM6427
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ABT-888 in Combination With Carboplatin and Gemcitabine in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: veliparib (ABT-888)|DRUG: carboplatin|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Effect and Safety of Autologous Umbilical Cord Blood Transfusion in the Treatment of Autism Spectrum Disorder
Status: RECRUITING
Conditions: Safety Issues;Effect of Drugs
Interventions: DRUG: 0.9% Sodium Chloride|BIOLOGICAL: Autologous Umbilical Cord Blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Target Temperature Management After Cardiac Arrest
Status: COMPLETED
Conditions: Out-of-hospital Cardiac Arrest
Interventions: PROCEDURE: Target temperature 36°C|PROCEDURE: Target Temperature 33°C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Upperlimb Sensorimotor Training in Hemiplegic Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Sensory training|OTHER: Motor training|OTHER: Conventional exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Analysis of Health Status of Сomorbid Adult Patients With COVID-19 Hospitalised in Fourth Wave of SARS-CoV-2 Infection
Status: COMPLETED
Conditions: COVID-19|Chronic Heart Failure|Diabetes Mellitus|Chronic Kidney Diseases|Ischemic Heart Disease|Arrythmia|Hypertensive Heart Disease|Overweight and Obesity|Oncology|Ischemic Stroke|Myocardial Infarction|Atrial Fibrillation|DVT|Stroke|Copd|Asthma|Pulmonary Embolism|Anemia|Myocarditis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Liraglutide Versus Insulin Mono-therapy in the Closed Loop Setting
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Closed loop with sensor and Insulin|DRUG: Closed loop with sensor, Insulin and Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interactive Guidance Therapy With Video Feed-back of Parent and Child With Autism Spectrum Disorder
Status: RECRUITING
Conditions: Autism Spectrum Disorders
Interventions: BEHAVIORAL: Baseline sessions TAU|BEHAVIORAL: Interactive guidance therapy|DIAGNOSTIC_TEST: Developmental and diagnostic assessments|BEHAVIORAL: Developmental assessment -Parental scales|BEHAVIORAL: Qualitative analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Safety and Effectiveness of HIFU Combined With REGOTORI for Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: PROCEDURE: high-intensity focused ultrasound therapy|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CARTOON: CoronAviRus (COVID-19) educaTional prOgram fOr childreN
Status: COMPLETED
Conditions: Covid19|Pediatric Psychiatric Disorder|Psychological Stress
Interventions: OTHER: Educational Program (CARTOON)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Open-Label, Multiple-Center, Phase IIa/IIb Clinical Trial to Evaluate the Efficacy, Safety and Tolerability of VG161 as Monotherapy and in Combination With Nivolumab for Treatment of Patients With Hepatocellular Carcinoma or Intrahepatic Cholangiocarcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Intrahepatic Cholangiocarcinoma
Interventions: DRUG: VG161|DRUG: Nivolumab Injection [Opdivo]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted Therapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myelogenous Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Chronic Myelomonocytic Leukemia|Recurrent Acute Lymphoblastic Leukemia|Recurrent Acute Myeloid Leukemia|Refractory Acute Lymphoblastic Leukemia|Refractory Acute Myeloid Leukemia
Interventions: OTHER: Antitumor Drug Screening Assay|DRUG: Dasatinib|DRUG: Idelalisib|OTHER: Laboratory Biomarker Analysis|DRUG: Pacritinib|OTHER: Pharmacological Study|DRUG: Ponatinib|DRUG: Ponatinib Hydrochloride|DRUG: Ruxolitinib|DRUG: Sorafenib|DRUG: Sorafenib Tosylate|DRUG: Sunitinib|DRUG: Sunitinib Malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rocking Motion: Physiologic Effect on the Surgical Stress Response
Status: COMPLETED
Conditions: Gastrointestinal Cancer
Interventions: PROCEDURE: Standard of Care|PROCEDURE: Rocking Chair Motion|BEHAVIORAL: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Three Novel Bi-treated Long Lasting Insecticidal Nets
Status: COMPLETED
Conditions: Malaria|Anaemia
Interventions: OTHER: Chlorfenapyr LLIN|OTHER: pyriproxyfen LLIN|OTHER: Piperonyl butoxide LLIN|OTHER: Standard LLIN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SGLT2 Inhibitor for Severe Tricuspid Regurgitation
Status: RECRUITING
Conditions: Tricuspid Regurgitation
Interventions: DRUG: Dapagliflozin Propanediol Hydrate 12.3 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shock Waves Therapy Combined With Leg Stretching in Patients With Plantar Fasciitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Plantar Fascitis
Interventions: OTHER: Real stretching|OTHER: Placebo stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Autologous Humanized Anti-CD19 and Anti-CD20 Dual Specific CAR-T Cells in Adult Patients With Diffuse Large B-cell Lymphoma
Status: RECRUITING
Conditions: Relapsed or Refractory DLBCL Patients With Either CD19 or CD20 Positive
Interventions: BIOLOGICAL: Autologous humanized anti-CD19 and anti-CD20 dual specific CAR-T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Canadian Trial of Bicalutamide in Patients Receiving Maintenance Avelumab for Metastatic Urothelial Cancer.
Status: WITHDRAWN
Conditions: Metastatic Urothelial Carcinoma
Interventions: DRUG: Bicalutamide 150 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Pelvic Floor Physical Therapy on Patients With 3rd and 4th Degree Obstetrical Lacerations
Status: UNKNOWN
Conditions: Obstetrical Lacerations|Obstetric; Injury Pelvic Floor
Interventions: BEHAVIORAL: Pelvic floor physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk Factors for Mortality in Cases of Obstructed Left Colonic Carcinoma
Status: COMPLETED
Conditions: Risk Factors for Mortality in Cases of Obstructed Left Colonic Carcinoma
Interventions: PROCEDURE: Resection|PROCEDURE: Stoma
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Acting Reversible Contraception
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: DMPA|DRUG: oral contraceptives|DRUG: Implanon®|DRUG: ParaGard®|DRUG: Mirena®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of SHR-1210, Gemcitabine and Cis-platinum by R/M NPC Subjects
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: BIOLOGICAL: SHR-1210|DRUG: Gemcitabine|DRUG: cis-platinum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptance and Commitment Therapy (ACT) in Early Psychosis Patients
Status: COMPLETED
Conditions: Acceptance and Commitment Therapy|Psychotic Disorders|Psychiatric Nursing
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Studying the Efficacy and Safety of IP2018 in Depressed, Erectile Dysfunction (ED) Patients
Status: UNKNOWN
Conditions: Erectile Dysfunction
Interventions: DRUG: IP2018|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Multimodal Neuroimaging Method for Diagnosis in Parkinsonian Syndromes
Status: COMPLETED
Conditions: Parkinson's Disease|Multiple System Atrophy
Interventions: OTHER: MRI acquisition|BEHAVIORAL: behavioral evaluations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Acupoint Stimulation Alleviates Postoperative Nausea and Vomiting
Status: UNKNOWN
Conditions: PONV
Interventions: DEVICE: transcutaneous electrical acupoint stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of Patient Preoperative Prep
Status: COMPLETED
Conditions: Surgical Skin Preparation
Interventions: DRUG: ZuraPrep|DRUG: ChloraPrep|DRUG: ZP Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Diagnostic Rest/Stress SPECT Results for Patients With Myocardial Ischemia and Infarction Using Myoview in Both Single and Dual Isotope Acquisition Approaches
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Technetium Tc99m Tetrofosmin injections|DRUG: Thallous Chloride T1-201
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Improvised Music to Enhance Intensive Interaction Version 1
Status: WITHDRAWN
Conditions: Child Development Disorders, Specific|Developmental Communication Disorders
Interventions: BEHAVIORAL: Intensive Interaction with Music|BEHAVIORAL: Standard Intensive Interaction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can tDCS Enhance Efficacy of Rehabilitative Intervention for Freezing of Gait in Parkinson's Disease?
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS|BEHAVIORAL: Rehabilitation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: