pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Portable Neuromodulation Stimulator (PoNS®) Therapy for Gait and Balance Deficits in Chronic Stroke Survivors: A Randomized Controlled Trial.
Status: RECRUITING
Conditions: Chronic Stroke Survivors
Interventions: DEVICE: Portable Neuromodulation Stimulator (PoNS)|DEVICE: Portable Neuromodulation Stimulator (PoNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dysport® In Migraine Without Aura Prophylaxis : DIMWAP Study
Status: COMPLETED
Conditions: Migraine Without Aura Prophylaxis
Interventions: DRUG: Botulinum Toxin type A (Dysport ® ) IM/SC 6-sites pericranial injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Open Versus Closed Reduction of Mandibular Sub-Condylar Fractures
Status: COMPLETED
Conditions: Mandibular Fractures
Interventions: PROCEDURE: Open Reduction & Internal Fixation|PROCEDURE: Closed Reduction & External Fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Approach in Inguinal Hernia Repair: Double Repair. A Prospective, Randomized, Controlled Clinical Trial
Status: UNKNOWN
Conditions: Hernia
Interventions: PROCEDURE: modified shouldice and double
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Direct vs Postoperative Ultrasound Guided Adductor Canal Nerve Block After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Osteoarthritis|Total Knee Arthroplasty|Nerve Block
Interventions: PROCEDURE: Intraoperative Block|PROCEDURE: Ultrasound Block|PROCEDURE: Intraoperative Placebo|PROCEDURE: Ultrasound Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Oral and Intestinal Microbiota in Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Psoriatic Arthritis|Periodontal Disease
Interventions: DRUG: doxycycline|DRUG: vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Mixed-methods Acceptability Study of ProACTive™ to Help Burns Patients Adjust to Changes to Appearance
Status: RECRUITING
Conditions: Burn Injuries|Burns|Emotional Distress|Adjustment
Interventions: OTHER: ProACTive™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PRAgmatic Trial in Atopic Dermatitis Testing Long-term Control Effectiveness of New Phototherapy Regimen During Winter Coupled With Oral Vitamin D Supplementation vs. Placebo
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Cholecalciferol|DRUG: Placebo of cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RN-Led Palliative and Supportive Care Intervention
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: OTHER: Palliative And supportive Care inTervention (PACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ET-blockade and Exercise-induced Vascular Adaptations in T2DM
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Bosentan|DRUG: Placebo|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination of Alemtuzumab and Rituximab at Low-doses in Refractory Chronic Graft-Versus-Host Disease
Status: COMPLETED
Conditions: Graft vs Host Disease
Interventions: DRUG: Alemtuzumab and rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Sphenopalatine Ganglion Block (SPGB) for Treatment of Postdural Puncture Headache (PDPH)
Status: TERMINATED
Conditions: Postdural Puncture Headache
Interventions: DRUG: 0.5% bupivacaine|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of AdCOVID in Healthy Adults (COVID-19 Vaccine Study)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: AdCOVID|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Zinc Bioavailability From Amaranth-enriched Maize Tortillas
Status: COMPLETED
Conditions: Nutritional Deficiency
Interventions: OTHER: Day 1: Maize Tortillas with 20% Amaranth|OTHER: Day 2 Maize Tortillas without 20% Amaranth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Trial of Cetuximab in Patients With Metastatic and/or Locally Advanced Soft Tissue and Bony Sarcomas
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: Cetuximab|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization of an Optically Pumped Magnetometer (OPM) Magnetoencephalography (MEG) Array
Status: RECRUITING
Conditions: Normal Physiology
Interventions: DEVICE: SQUID MEG|DEVICE: OPM MEG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Value of Potassium Magnesium Citrate in Preventing and Treating Hypertension in African Americans
Status: NOT_YET_RECRUITING
Conditions: Hypertension
Interventions: DRUG: KMgCit|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Maxillary Patient Specific Implants in Bimaxillary Orthognathic Surgery
Status: RECRUITING
Conditions: Retrognathia|Malocclusion, Angle Class II
Interventions: DEVICE: Patient-specific implants|DEVICE: Conventional mini-plates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Diagnosis and Treatment of Depression Based on Biological Evidence of Dopamine Reward Pathway
Status: UNKNOWN
Conditions: Diagnosis and Treatment of Depression
Interventions: DRUG: risperidone|DRUG: aripiprazole|DRUG: bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Humidity Under Continuous Positive Airway Pressure
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: RESMed S9 with humidifier H5i and heated tube Climate Line|DEVICE: CPAP without humidification|DEVICE: CPAP with heated humidification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Delayed Heterologous SARS-CoV-2 Vaccine Dosing (Boost) After Receipt of EUA Vaccines
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Ad26.COV2.S|BIOLOGICAL: BNT162b2|BIOLOGICAL: mRNA-1273|BIOLOGICAL: mRNA-1273.211|BIOLOGICAL: mRNA-1273.222|BIOLOGICAL: SARS-CoV-2 rS/M1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Postoperative Dexamethasone on Post-Cesarean Pain
Status: RECRUITING
Conditions: Post-Cesarean Pain|Cesarean Section Complications
Interventions: DRUG: Dexamethasone|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluate the Effects of Repeated Periods of Modified Fasting to Support Healthy Natural Weight Management and Prevention of Weight Gain
Status: COMPLETED
Conditions: Body Weight Changes
Interventions: DIETARY_SUPPLEMENT: Meal replacement shake|DIETARY_SUPPLEMENT: Multivitamin and mineral capsules|DIETARY_SUPPLEMENT: Fish oil with sesame lignans and olive extract softgel|DIETARY_SUPPLEMENT: Prebiotic Chewable tablet|DIETARY_SUPPLEMENT: Clove Extract and Maqui Berry extract capsule|DIETARY_SUPPLEMENT: .Whole Food Blend capsule|DIETARY_SUPPLEMENT: Turmeric extract capsule|DIETARY_SUPPLEMENT: European White Kidney Bean capsule|DIETARY_SUPPLEMENT: Saffron extract capsule|DIETARY_SUPPLEMENT: Ubiquinol with Fulvic acid complex softgel|DIETARY_SUPPLEMENT: Calcium with Hesperidin and gynostemma extract tablet|DIETARY_SUPPLEMENT: Multivitamin and mineral supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: MAKv1 Exoskeleton for TKA Patients: a Safety, Usability and Clinical Effects Trial of an Early Intervention
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: DEVICE: MAKv1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ixabepilone in Treating Patients With Recurrent or Persistent Leiomyosarcoma of the Uterus Previously Treated With Chemotherapy
Status: COMPLETED
Conditions: Recurrent Uterine Corpus Sarcoma|Uterine Corpus Leiomyosarcoma
Interventions: DRUG: Ixabepilone|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studyof Allogeneic Hematopoietic Stem Cell Transplantation From One Haplotype Mismatch Related Donor or From an Unrelated Donor in Elderly Patients
Status: COMPLETED
Conditions: Hematologic Neoplasms
Interventions: BIOLOGICAL: Allogeneic (Allo) hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multifocal Lens Centration and Its Effect on Visual Performance in a Presbyopic Population
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: Acuvue Oasys for Presbyopia|DEVICE: PureVision2 for Presbyopia|DEVICE: Biofinity Multifocal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: NeuroCardio Baby Research Outpatient Clinic: Study on the Neurodevelopment of Infants With Congenital Heart Disease in Brazil
Status: RECRUITING
Conditions: Congenital Heart Disease|Child Development|Early Intervention
Interventions: BEHAVIORAL: Remotely monitored parent-mediated hybrid home and clinic based multidisciplinary Early Intervention protocols.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of the Infections on Osteo-articular Prostheses by 6 Versus 12 Weeks of Antibiotherapy
Status: COMPLETED
Conditions: Prosthesis-related Infections
Interventions: OTHER: duration of antibiotic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy of Xiaopi Granules and Decoction in Triple-negative Breast Cancer: a Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Triple Negative Breast Neoplasms
Interventions: DRUG: Xiaopi granules|DRUG: Xiaopi decoction|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Venetoclax, Cladribine, Low Dose Cytarabine, and Azacitidine in Treating Patients With Previously Untreated Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Azacitidine|DRUG: Cladribine|DRUG: Cytarabine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Maintenance Therapy With Bevacizumab After Induction in Metastatic Colorectal Cancer (CRC)
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: 5-Fluorouracil, Folic acid, Capecitabine; Bevacizumab|DRUG: 5-Fluorouracil, Folic acid, Capecitabine; Bevacizumab|DRUG: 5-Fluorouracil, Folic acid, Capecitabine; Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Carbohydrate Intake > 44kCal Per Hour During Labour on the Rate of Instrumental Vaginal Delivery
Status: UNKNOWN
Conditions: Delivery Complication|Labor Long|Pregnancy Related
Interventions: DIETARY_SUPPLEMENT: carbohydrate oral intake|OTHER: free water only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of an Antiinflammatory Diet on Postprandial Gene Expression of Mononuclear Cells of Adult Obese Women
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: FAWGT diet|OTHER: Usual diet (UD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Nandrolone Decanoate and Leucine on Muscle Loss
Status: COMPLETED
Conditions: Muscle Atrophy
Interventions: BEHAVIORAL: Inactivity|DRUG: ND|DIETARY_SUPPLEMENT: Leu
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Dose-response Profiles of Uterotonics After Initial Carbetocin Administration - an Ex-vivo Study in Desensitized Human Myometrium
Status: RECRUITING
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Carbetocin|DRUG: Oxytocin|DRUG: Carbetocin|DRUG: Oxytocin|DRUG: Ergonovine|DRUG: Carboprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intubating Conditions During Rapid Sequence Induction in Elderly With Either Suxamethonium 1.0 mg/kg or Rocuronium 1.0 mg/kg
Status: COMPLETED
Conditions: Intubation Conditions
Interventions: DRUG: Suxamethonium|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Trauma-sensitive Yoga and Tai Chi on Mental Health
Status: SUSPENDED
Conditions: Mental Health Wellness 1
Interventions: BEHAVIORAL: Trauma-Sensitive Yoga + TAU|BEHAVIORAL: Chen Style Tai Chi + TAU|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Bifeprunox in Patients With Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Bifeprunox|DRUG: Placebo|DRUG: Quetiapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of MYOBLOC® Followed by Open-Label Multiple-Treatment With MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adult Subjects
Status: COMPLETED
Conditions: Sialorrhea
Interventions: DRUG: MYOBLOC|OTHER: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The PASTDUe Nutrition Ecosystem Project (PASTDUe)
Status: RECRUITING
Conditions: Diet, Healthy|Food|Nutrition|Intensive Care|Abdominal Trauma|Surgery|Intra-abdominal Infection|Sepsis|Ischemic Bowel|Vascular|Penetrating Abdominal Trauma|Enteral Feeding|Oral
Interventions: COMBINATION_PRODUCT: Nutrition Ecosystem pathway|OTHER: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Based Family Psychoeducation Intervention for Early Psychosis
Status: COMPLETED
Conditions: Psychotic Disorder
Interventions: BEHAVIORAL: Mindfulness-Based Family Psycho-Education (MBFBE)|BEHAVIORAL: Family Psycho-Education (FPE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bevacizumab and PEG-Interferon Alfa-2b in Treating Patients With Metastatic or Unresectable Carcinoid Tumors
Status: COMPLETED
Conditions: Metastatic Gastrointestinal Carcinoid Tumor|Recurrent Gastrointestinal Carcinoid Tumor|Regional Gastrointestinal Carcinoid Tumor
Interventions: BIOLOGICAL: PEG-interferon alfa-2b|BIOLOGICAL: bevacizumab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Fecal Microbiota Transplant Dosing for Mild to Moderate Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: BIOLOGICAL: Fecal Microbiota Transplantation (FMT), OpenBiome|OTHER: pretreatment antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Immunogenicity of Repeated rhC1INH Administration
Status: COMPLETED
Conditions: Genetic Disorders|Hereditary Angioedema
Interventions: DRUG: Recombinant Human C1 Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study Of Oral Glecaprevir/Pibrentasvir Tablet In Pediatric (12 Years and Older) And Adult Treatment-Naive Participants With Chronic Hepatitis C Genotypes 1 To 6 And Liver Cirrhosis
Status: COMPLETED
Conditions: Hepatitis C Virus (HCV)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cancer Chemoprevention by Metformin Hydrochloride in Oral Potentially Malignant Lesions
Status: UNKNOWN
Conditions: Oral Cancer
Interventions: DRUG: Metformin Hydrochloride 500 MG|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adaptation of the Friendship Bench Intervention for HIV-infected Perinatal Women in Lilongwe
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|Perinatal Depression
Interventions: BEHAVIORAL: Enhanced Friendship Bench|OTHER: Enhanced Standard Care (Control)|BEHAVIORAL: Adapted Friendship Bench
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Prevent Acute Kidney Injury After Cardiac Surgery Involving Cardiopulmonary Bypass
Status: UNKNOWN
Conditions: Acute Kidney Injury
Interventions: DRUG: ANG-3777|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Static Helical Screw Locking of Pertrochanteric Femur Fractures Using the TFN-A
Status: RECRUITING
Conditions: Pertrochanteric Fracture
Interventions: PROCEDURE: Dynamic Rotational Locking|PROCEDURE: Static Locking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Combination Chemotherapy in Treating Patients With Diffuse Large B-Cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Large B Cell Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: doxorubicin|DRUG: vincristine|DRUG: prednisone|DRUG: etoposide|DRUG: filgrastim|DRUG: pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Botanical PHY906 Plus Capecitabine for Advanced Unresectable Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Liver Cancer
Interventions: DRUG: PHY906|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Everolimus and Imatinib Mesylate in Treating Patients With Metastatic or Unresectable Kidney Cancer
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: DRUG: Everolimus|DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesia With Local Infiltration After Hip Fracture Of Intertrochanteric Type
Status: COMPLETED
Conditions: Hip Fracture of Intertrochanteric Type
Interventions: DRUG: Ropivacaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Body Acceptance Programs for Young Men
Status: ACTIVE_NOT_RECRUITING
Conditions: Body Image Disturbance|Eating Disorder Symptom|Eating Behavior|Dysmorphic Features|Dysmorphic Disorder, Body|Dysmorphia|Eating Disorders|Exercise, Compulsive
Interventions: BEHAVIORAL: Media Advocacy (MA)|BEHAVIORAL: More than Muscles (MTM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stereotactic Body Radiotherapy for Unresectable Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Localized Non-Resectable Adult Hepatocellular Carcinoma
Interventions: RADIATION: Stereotactic body radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Consultation for Type 2 Diabetes Patients in Real Life
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Specific consultation for physical activity counseling|BEHAVIORAL: Consultation for physical activity counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Early Parecoxib Usage to Decreases Narcotic Requirement and Length of Stay After Traumatic Rib Fracture
Status: TERMINATED
Conditions: Parecoxib|Rib Fractures
Interventions: DRUG: Parecoxib|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: QUILT-3.064: PD-L1 t-haNK In Subjects With Locally Advanced Or Metastatic Solid Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Solid Tumor|Metastatic Cancer|Solid Tumor
Interventions: BIOLOGICAL: PD-L1 t-haNK
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrated Telehealth After Stroke Care
Status: WITHDRAWN
Conditions: Blood Pressure|Stroke, Ischemic|Stroke Hemorrhagic
Interventions: BEHAVIORAL: Integrated Telehealth After Stroke Care|BEHAVIORAL: Usual post-stroke follow-up care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Capeox Regimen Combined With Sintilimab and Bevacizumab for Gastric Cancer
Status: RECRUITING
Conditions: Stomach Neoplasm
Interventions: COMBINATION_PRODUCT: Capeox regimen combined with Sintilimab and Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Education Techniques on the Acquisition of the Mothering Role
Status: UNKNOWN
Conditions: Gaining the Role of Motherhood in Primipara Pregnancy (Focus)
Interventions: BEHAVIORAL: Face to face education|BEHAVIORAL: Web based education|BEHAVIORAL: No education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Platform Trial for Gram Negative Bloodstream Infections
Status: RECRUITING
Conditions: Gram-negative Bacteremia
Interventions: OTHER: De-escalation VS No De-escalation|OTHER: Oral beta-lactams VS non beta-lactams|OTHER: Central vascular catheter retention VS Central vascular catheter replacement|OTHER: Cephalosporin VS Carbapenem for low risk AmpC organisms|OTHER: Routine follow-up blood culture VS No routine follow-up blood culture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glutamine Challenge as Predictor of Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt (TIPS)
Status: TERMINATED
Conditions: Refractory Ascites|Hepatic Hydrothorax|Hepatic Encephalopathy|Cirrhosis
Interventions: OTHER: Oral glutamine challenge|OTHER: Psychometric Tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Palmaris Longus Muscle and Dupuytren
Status: RECRUITING
Conditions: Dupuytren's Disease
Interventions: PROCEDURE: Non-invasive tests to determine the presence or absence of the palmaris longus tendon in both hands.|PROCEDURE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of LOW-molecular-weight Heparin in Reducing Radial Artery Occlusion Rate After Transradial Coronary Catheterization
Status: COMPLETED
Conditions: Arterial Occlusion
Interventions: DRUG: low molecular weight heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of ChAd63/MVA METRAP + RTS,S
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria
Interventions: BIOLOGICAL: RTS,S/AS01B|BIOLOGICAL: ChAd63 ME-TRAP|BIOLOGICAL: MVA ME-TRAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult Kidney Wilms Tumor|Beckwith-Wiedemann Syndrome|Childhood Kidney Wilms Tumor|Diffuse Hyperplastic Perilobar Nephroblastomatosis|Rhabdoid Tumor of the Kidney|Stage I Kidney Wilms Tumor|Stage II Kidney Wilms Tumor|Stage III Kidney Wilms Tumor|Stage IV Kidney Wilms Tumor|Stage V Kidney Wilms Tumor
Interventions: BIOLOGICAL: Dactinomycin|DRUG: Doxorubicin Hydrochloride|RADIATION: Radiation Therapy|PROCEDURE: Therapeutic Conventional Surgery|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Hemarthrosis in Tibial Tubercle Osteotomy by the Administration of Intravenous Tranexamic Acid
Status: COMPLETED
Conditions: Tibial Tubercle Osteotomy
Interventions: DRUG: Tranexamic Acid (TXA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomised Controlled Trial Assessing the Impact of Genital Herpes Suppressive Therapy on HIV Shedding
Status: COMPLETED
Conditions: Herpes Genitalis|HIV Infection
Interventions: DRUG: Valacyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Immune Response and Potential Booster for Patients Who Have Received HER2-pulsed DC1
Status: TERMINATED
Conditions: Breast Cancer|HER2-positive Breast Cancer|HER-2 Gene Amplification|HER2 Positive Breast Carcinoma|HER-2 Protein Overexpression|Breast Cancer, Male|Breast Cancer Female
Interventions: BIOLOGICAL: HER2 DC1 Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Neurodegeneration and Neuronal Fluctuations in Lewy Body Disease and Alzheimer's Disease
Status: RECRUITING
Conditions: Lewy Body Disease|Alzheimer Disease|Healthy
Interventions: DIAGNOSTIC_TEST: Magnetic Resonance Imaging|DIAGNOSTIC_TEST: Electroencephalography|DIAGNOSTIC_TEST: Electromyography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Annual Study to Investigate Inactivated Subunit Influenza Vaccine Due to New Virus Strains for the 08/09 Season.
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Trivalent influenza subunit vaccine Influvac
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized Control Trial of ZEPHYRx Gamified Incentive Spirometry Compared to Traditional Spirometry
Status: UNKNOWN
Conditions: Thoracic Surgery|Respiratory Therapy
Interventions: DEVICE: ZEPHYRx Respiratory Therapy (RT) System|DEVICE: Standard Incentive Spirometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pectoralis Block vs Paravertebral Nerve Blocks for Breast Surgery
Status: COMPLETED
Conditions: Breast Surgery
Interventions: DRUG: Pecs-2 block (single injection)|DRUG: Paravertebral block (single injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy Study for Epoetin Alfa in Anemic Patients With Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Group 2: Placebo|DRUG: Group 1: Epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Blood Stem Cell Transplantation
Status: COMPLETED
Conditions: Hodgkin's Disease
Interventions: PROCEDURE: Allogeneic Blood Stem Cell Transplantation|DRUG: Fludarabine|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity Study of Antibody Persistence and Booster Effect of DTaP-HB PRP~T Combined Vaccine in Filipino Infants
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Hepatitis B|Influenza
Interventions: BIOLOGICAL: DTaP-HB PRP~T Combined Vaccine|BIOLOGICAL: DTaP-HB-PRP~T vaccine|BIOLOGICAL: Oral Polio Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bortezomib in Treating Patients With Unresectable or Metastatic Gastric Cancer or Gastroesophageal Junction Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ziprasidone Versus Olanzapine In The Treatment Of Schizophrenia.
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Ziprasidone|DRUG: Olanzapine|PROCEDURE: Scales|PROCEDURE: measures of the body (Weight...)|PROCEDURE: Serum analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Vitamin D3 in Diabetic Kidney Disease
Status: COMPLETED
Conditions: Diabetes Mellitus|Chronic Kidney Disease|Diabetic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Equivalence of Three Products Containing Metronidazole Benzoate.
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: DRUG: Metronidazole benzoate|DRUG: Flagyl 125 mg/5 ml oral suspension|DRUG: Flagyl 400 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Penehyclidine Hydrochloride Inhalation and 3-year Outcome After Surgery
Status: COMPLETED
Conditions: Postoperative Complications|Long-term Outcome
Interventions: DRUG: Penehyclidine inhalation|DRUG: Placebo inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: FDG-PET As an Imaging Modality to Diagnose and Risk Stratify Subclinical, Imaging Negative Ici-Myocarditis
Status: NOT_YET_RECRUITING
Conditions: Subclinical Immune Checkpoint Inhibitor-Induced Myocarditis|Myocarditis|ICI-Myocarditis|Solid Malignant Tumor|Hematologic Malignancy|Subclinical Myocarditis|Subclinical ICI-myocarditis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Timing of Surgery and the Evolution of Postoperative Outcomes in Breast Cancer Patients Undergoing Surgical Intervention Following Recovery From SARS-CoV-2 Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|COVID-19|Postoperative Complications
Interventions: OTHER: Preoperative resolved COVID-19
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Surgical Innovation for Diabetes Treatment 2
Status: RECRUITING
Conditions: Enteroendocrine Physiological Changes in Superobese Patients Submitted to Two Different Bariatric Procedures|Determine Whether BPD With DS or SADI-S as Primary or Revisional Surgery is Superior Than the Other as First Choice for the Superobese|Determine Whether or Not Revision Surgery is as Effective as Primary Surgery and Understand the Physiological Mechanisms Inherent in These Putative Differences
Interventions: PROCEDURE: Single anastomosis duodeno-ileal bypass|PROCEDURE: Biliopancreatic diversion with duodenal switch|PROCEDURE: SADI-S as a revisional procedure|PROCEDURE: BPD-DS as a revisional procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CBT vs RTW Intervention for Patients With Common Subclinical Mental Illness in Primary Care
Status: COMPLETED
Conditions: Anxiety Disorders|Major Depression|Stress Disorders|Primary Insomnia
Interventions: BEHAVIORAL: Cognitive behavior therapy|BEHAVIORAL: Return to work
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Time Interval for Changing Closed System Suction Catheters, Effect on Ventilator Associated Pneumonia
Status: COMPLETED
Conditions: Pneumonia, Ventilator Associated|Closed System Suction Catheter
Interventions: DEVICE: Closed system suction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Treatment Plan for an Individual Patient With Pasireotide for Hyperinsulinemic Hypoglycemia
Status: COMPLETED
Conditions: Hyperinsulinemic Hypoglycemia|Post Gastrointestinal Tract Surgery Hypoglycaemia
Interventions: DRUG: Pasireotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Telepractice and Conventional Face-to-face Voice Therapy
Status: COMPLETED
Conditions: Dysphonia|Aged|Speech Therapy
Interventions: BEHAVIORAL: Vocal Training Via Telepractice|BEHAVIORAL: Vocal Training Via face-to face practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Treatment of Obstructed Defecation Syndrome
Status: UNKNOWN
Conditions: Sensation of Inadequate Defecation|Rectal Prolapse|Rectocele
Interventions: PROCEDURE: STARR|PROCEDURE: Laparoscopic Ventral Rectopexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Preoperative Ultrasound Guided Pectoralis Nerve Block Placement Versus Intra-operative Placement: A Prospective Randomized Trial
Status: TERMINATED
Conditions: Post-operative Pain
Interventions: DEVICE: On-Q|DRUG: Ultrasound guided pectoral nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0106 Cytarabine and Daunorubicin w/ or w/o Gemtuzumab Followed By HD Cytarabine and Either Gemtuzumab or Nothing in de Novo AML
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: gemtuzumab ozogamicin|OTHER: observation|DRUG: Cytosine arabinoside|DRUG: Daunomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of COVAC-2 in Adults
Status: COMPLETED
Conditions: Severe Acute Respiratory Syndrome Coronavirus 2
Interventions: BIOLOGICAL: COVAC-2|BIOLOGICAL: Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Effect Of Rifaximin on the Gut Microbiota and Metabolome in SIBO Using CapScan®
Status: RECRUITING
Conditions: Small Intestinal Bacterial Overgrowth
Interventions: DEVICE: CapScan collection capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: NBI Combined With MRI to Guide CTV Optimization in Eccentric Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma by AJCC V8 Stage
Interventions: RADIATION: CTV optimized IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TLC D-99 and Ifosfamide in Metastatic Soft Tissue Sarcoma Patients
Status: COMPLETED
Conditions: Sarcoma, Soft Tissue
Interventions: DRUG: combination of TLC D-99 and Ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trinity™ BIOLOX Delta™ CoC THR Multi-center Study
Status: UNKNOWN
Conditions: Osteoarthritis|Avascular Necrosis|Rheumatoid Arthritis|CDH
Interventions: DEVICE: Trinity CoC Total Hip System|DEVICE: Trinity Ceramic-on-Poly THR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine and Propofol in Mechanically Ventilated Patients by Using Salivary Alpha-amylase as a Stress Marker
Status: COMPLETED
Conditions: Dexmedetomidine|Propofol|Mechanical Ventilation|Salivary Alpha Amylase|Stress
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma
Status: TERMINATED
Conditions: High Grade Sarcoma|Metastatic Leiomyosarcoma|Metastatic Malignant Peripheral Nerve Sheath Tumor|Metastatic Synovial Sarcoma|Metastatic Undifferentiated Pleomorphic Sarcoma|Metastatic Unresectable Sarcoma|Myxofibrosarcoma|Recurrent Leiomyosarcoma|Recurrent Malignant Peripheral Nerve Sheath Tumor|Recurrent Synovial Sarcoma|Recurrent Undifferentiated Pleomorphic Sarcoma|Stage III Uterine Corpus Leiomyosarcoma AJCC v8|Stage IIIA Uterine Corpus Leiomyosarcoma AJCC v8|Stage IIIB Uterine Corpus Leiomyosarcoma AJCC v8|Stage IIIC Uterine Corpus Leiomyosarcoma AJCC v8|Stage IV Uterine Corpus Leiomyosarcoma AJCC v8|Stage IVA Uterine Corpus Leiomyosarcoma AJCC v8|Stage IVB Uterine Corpus Leiomyosarcoma AJCC v8|Unresectable Leiomyosarcoma
Interventions: DRUG: Pazopanib|DRUG: Pazopanib Hydrochloride|DRUG: Sapanisertib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Strength Training and Whole Body Vibration in Healthy Elderly
Status: WITHDRAWN
Conditions: Health Behavior
Interventions: BEHAVIORAL: Strength training group|BEHAVIORAL: Control group|BEHAVIORAL: Whole-body vibration training group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: HE4 in the Diagnostic Approach of Endometrial Cancer in Patients With Postmenopausal Bleeding
Status: UNKNOWN
Conditions: Endometrial Neoplasms|Postmenopause|Uterine Hemorrhage|Cancer Biomarker|CA 125 Antigen
Interventions: OTHER: Patients with Post menopausal bleeding|DIAGNOSTIC_TEST: CA125 and HE4 assays
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Core Stability Exercises on Foot Posture, Function and Limb Alignment in Flexible Flat Feet Patients
Status: NOT_YET_RECRUITING
Conditions: Flexible Flatfoot
Interventions: OTHER: Core stability exercises and Short foot exercises|OTHER: Conventional foot exercises and short foot exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Doses Amitriptyline & Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: DRUG: Amitryptiline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Theempowerment in Patients With Severe Breast Fibrosis Radio-induced Treated by Pravastatin : Benefit of e-PROs (Electronic " Patient Reported Outcome ") on Breast-related Quality of Life
Status: RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: e-PRO Intervention|DRUG: Pravastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multidisciplinary Approach Versus Conventional Approach in Colonic Preparation of Hospitalized Patients
Status: UNKNOWN
Conditions: Bowel Preparation for Colonoscopy
Interventions: BEHAVIORAL: Education|OTHER: Fiber free diet|DIETARY_SUPPLEMENT: Adjuvants|DRUG: Polyethylene glycol (PEG)|DRUG: Bisacodyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of VX-371 in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del-CFTR Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: VX-371 + HS|DRUG: Hypertonic saline|DRUG: Placebo|DRUG: Orkambi|DRUG: VX-371
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Single and Multiple Oral Doses of 40 mg Telmisartan/5 mg Amlodipine and 80 mg Telmisartan/5 mg Amlodipine in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Telmisartan low|DRUG: Telmisartan high|DRUG: amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of All-Trans-Retinoic Acid in Combination With Interferon-Alpha 2a in Children With Recurrent Neuroblastoma or Wilms' Tumor
Status: COMPLETED
Conditions: Nephroblastoma|Neuroblastoma
Interventions: DRUG: IFN-alpha with retinoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparing a Monthly Replacement Lens Versus a Daily Disposable Lens
Status: COMPLETED
Conditions: Myopia|Hyperopia
Interventions: DEVICE: Control Contact Lens|DEVICE: Test Contact Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Trial Between 3 Types of Insulin Infusion Protocols
Status: COMPLETED
Conditions: Hyperglycemia
Interventions: PROCEDURE: Glucommander-Guided Intravenous Insulin Infusion|PROCEDURE: Standard Intravenous Insulin Infusion|PROCEDURE: Simple Calculated Intravenous Insulin Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measuring Cerebral Blood Flow Using Pseudo-continuous Arterial Spin Labeling Perfusion Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Traumatic Brain Injury|Multiple Sclerosis|Alzheimer's Disease|Tumor
Interventions: DEVICE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Levomilnacipran ER (F2695 SR) in Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Levomilnacipran ER|DRUG: Levomilnacipran ER|DRUG: Levomilnacipran ER|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Chlamydia Vaccine CTH522 in Healthy Women Aged 18 to 45 Years
Status: COMPLETED
Conditions: Chlamydia Trachomatis
Interventions: BIOLOGICAL: CTH522-CAF01|BIOLOGICAL: CTH522-Al(OH)3|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION