pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Efficacy of the Transfusion of UCB in Patients With an ASD Depending on the Degree of HLA Compatibility.
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Autism
Interventions: BIOLOGICAL: ASD CB-MNC infusion low level HLA compatibility.|BIOLOGICAL: ASD CB-MNC infusion high level HLA compatibility.|OTHER: Standard therapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Chemotherapy De-escalation in Early-Stage HER2 Positive Breast Cancer
Status: SUSPENDED
Conditions: HER2-positive Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: Carboplatin|DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Trastuzumab emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study 08-114 Open-label Extension of Study 08-110 - A Multi-Center Study of Denufosol Tetrasodium Inhalation Solution in Patients With Cystic Fibrosis Lung Disease (P08642)
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DRUG: Denufosol tetrasodium Inhalation Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Aspirin Desensitization on Patients With Aspirin-exacerbated Respiratory Diseases
Status: COMPLETED
Conditions: Asthma, Aspirin-Induced
Interventions: DRUG: aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of EV-077 in Type 2 Diabetic Subjects
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DRUG: EV-077|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Arsenic Trioxide and Gemtuzumab Ozogamicin in Treating Patients With Advanced Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: arsenic trioxide|DRUG: gemtuzumab ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increased Femoral Anteversion and Physical Performance
Status: COMPLETED
Conditions: High Femoral Anteversion|Muscle Strength|Flexibility|Functional Performance|Functional Capacity
Interventions: OTHER: Sit and reach test|OTHER: Hand grip strength measurement|OTHER: Back-leg-chest muscle strength measurement|OTHER: Functional performance|OTHER: Functional capacity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adductor Canal Block Versus Femoral Nerve Block for Total Knee Arthroplasty
Status: COMPLETED
Conditions: Arthropathy of Knee
Interventions: PROCEDURE: Adductor Canal Nerve Block|DRUG: Femoral Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Blood, Hair and Lung Concentrations of Metals and Metalloids in Patients With Lung Cancer or Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Lung Cancer|Chronic Obstructive Pulmonary Disease|Emphysema|Lung Surgery
Interventions: PROCEDURE: Lung surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Paracetamol Oral Paediatric Suspension at 4.8% : Study of Acceptability and Safety.
Status: COMPLETED
Conditions: Fever|Pain
Interventions: DRUG: paracetamol 4.8% paediatric oral suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: EndoClot for Hemostasis and Preventing Post-procedure Bleeding After Endoscopic Mucosal Resection
Status: COMPLETED
Conditions: Endoscopic Hemostasis|Colonic Polyps
Interventions: PROCEDURE: Hemoclip|PROCEDURE: EndoClot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Based Approaches to Insomnia
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction|BEHAVIORAL: Mindfulness-Based Therapy for Insomnia|BEHAVIORAL: Wait-List + Behavioral Therapy for Insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Compare Visual Performance of Two Trifocal IOLs
Status: COMPLETED
Conditions: Cataract|Lens Opacities|Presbyopia
Interventions: DEVICE: IOL implantation experimental|DEVICE: IOL implantation active comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ENDOCUR - Modulation of Endotoxaemia Via Curcumin Intake in Healthy Overweight Adults
Status: COMPLETED
Conditions: Overweight
Interventions: DIETARY_SUPPLEMENT: BCM-95|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Combined Inhalational With Intravenous Amphotericin B Versus Intravenous Amphotericin B Alone for Pulmonary Mucormycosis
Status: COMPLETED
Conditions: Pulmonary Mucormycosis
Interventions: DRUG: Inhaled amp B deoxycholate+intravenous liposomal amp B|DRUG: Intravenous liposomal amphotericin B alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Bioequivalence of Ruxolitinib Extended Release (XR) Tablets With Ruxolitinib Immediate Release (IR) Tablets Administered Orally in Healthy Participants
Status: NOT_YET_RECRUITING
Conditions: Healthy Participants
Interventions: DRUG: Ruxolitinib IR|DRUG: Ruxolitinib XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wear Behavior of Milled Posterior Crowns Fabricated From the New Monolithic Zirconia 5Y-TZP/3Y-TZP Compared to Lithium Disilicate
Status: UNKNOWN
Conditions: Posterior Teeth|Worn Posterior Teeth|Endodontically Treated Teeth|Crowned Posterior Teeth
Interventions: OTHER: monolithic zirconia (5Y-TZP/3-YTZ) ZirCAD Prime.|OTHER: Lithium Dislicate IPS e.max crown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Concentrated Cross-disciplinary Group Intervention for Common Health Complaints (Including Post COVID-19 Fatigue)
Status: UNKNOWN
Conditions: Mixed Anxiety Depression|Diabetes Mellitus, Type 2|Low Back Pain|Chronic Obstructive Pulmonary Disease|COVID-19
Interventions: OTHER: Interdisciplincary concentrated group rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison Between Efficacy of Topical Sildenafil 2% and Topical Minoxidil 5% in Treatment of Androgenic Alopecia
Status: UNKNOWN
Conditions: Androgenic Alopecia
Interventions: DRUG: Sildenafil 2%|DRUG: Minoxidil 5 %
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Therapy to Improve Myocardial Function in Patients With Acute Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: PROCEDURE: Autologous bone marrow-derived stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recurrent Bacterial Vaginosis and Vaginal Acidifying Gel Trial
Status: COMPLETED
Conditions: Bacterial Vaginosis
Interventions: DRUG: Vaginal acidifying gel (RepHresh)|DRUG: Metronidazole control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Changes of ETT Cuff Pressures After Head and Neck Positions Placed for Adenotonsillectomy and Tonsillectomy in Children
Status: COMPLETED
Conditions: Endotracheal Tube Cuff Pressure|Adenotonsillectomy|Tonsillectomy|Position
Interventions: OTHER: Intracuff pressure measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Calcium Supplement Particle Size and Vitamin D Supplement on Calcium Retention in Adolescent Girls
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DIETARY_SUPPLEMENT: Small Particle Size Calcium Carbonate Supplement|DIETARY_SUPPLEMENT: Large Particle Size Calcium Carbonate Supplement|DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Calcium Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Evaluation of Taste Function In Multiple Myeloma Patients Undergoing Autologous Hematopoietic Cell Transplantation
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DIAGNOSTIC_TEST: Oral microbiota assessment|DIAGNOSTIC_TEST: Comprehensive chemical gustometry|DIAGNOSTIC_TEST: Measurement of salivary flow|BEHAVIORAL: Surveys assessing taste disturbances
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Real World Testing of a Brain-Computer Interface
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis|Brain Stem Stroke|Cerebral Palsy|Traumatic Brain Injury|Speech Disorders
Interventions: BEHAVIORAL: Speech generating device (SGD) evaluation including BCI access|BEHAVIORAL: Training and treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low-Level Laser Therapy for Plantar Fasciitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Plantar Fascitis
Interventions: DEVICE: Photobiomodulation Therapy (PBMT)|DEVICE: Sham-Photobiomodualtion Therapy (Sham-PBMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of Liver Diseases Using a Deep-Learning Approach Based on Ultrasound RF-Data
Status: RECRUITING
Conditions: Artificial Intelligence|Ultrasonography|Elasticity Imaging Techniques|Liver Diseases|Metastasis to Liver
Interventions: DEVICE: Collection of elastography data|DEVICE: Collection of ultrasonic raw data
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Extension Study to Evaluate the Immunogenicity and Safety of the Second Dose of GBS Trivalent Vaccine in Healthy Non-Pregnant Subjects.
Status: COMPLETED
Conditions: Bacterial Infection Due to Streptococcus, Group B|Streptococcus Agalactiae
Interventions: BIOLOGICAL: GBS Trivalent Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 1 Study To Evaluate Tolerability, Safety, And Pharmacokinetics Of Topical PF-06263276 In Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06263726|DRUG: PF-06263726|DRUG: PF-06263726|DRUG: Placebo|DRUG: PF-06263726|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treating Postmenopausal Dyspareunia Where it Hurts
Status: COMPLETED
Conditions: Dyspareunia
Interventions: DRUG: 50mcg estradiol cream|DRUG: 100mcg estradiol cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Fish Skin Extracellular Matrix (ECM) to Facilitate Chronic Wound Healing
Status: COMPLETED
Conditions: Pressure Ulcers|Venous Ulcers|Diabetic Ulcers|Chronic Ulcer of Foot|Trauma-related Wound
Interventions: DEVICE: Marigen Wound Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial With Subcutaneous Alemtuzumab and Oral Fludarabinephosphate for the Determination of Safety, Efficacy and Molecular Profiling for the Prediction of Response
Status: COMPLETED
Conditions: B-cell Chronic Lymphocytic Leukemia
Interventions: DRUG: Fludarabine phosphate|DRUG: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib, Obinutuzumab and Chlorambucil in Treatment naïve CLL
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Acalabrutinib|DRUG: Obinutuzumab|DRUG: Chlorambucil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Nitric Oxide Reduction in Patients With Cardiogenic Shock After a Heart Attack
Status: TERMINATED
Conditions: Shock, Cardiogenic
Interventions: DRUG: Tilarginine Acetate Injection intravenous infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: PErfusioN, OxyGen ConsUmptIon and ENergetics in ADPKD (PENGUIN)
Status: COMPLETED
Conditions: Polycystic Kidney Disease, Adult|Polycystic Kidney, Autosomal Dominant
Interventions: DRUG: Aminohippurate Sodium Inj 20%|DRUG: Iohexol Inj 300 milligrams per milliliter (MG/ML)|RADIATION: PET/CT Scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Zinc Sulfate in Preventing Loss of Sense of Taste in Patients Undergoing Radiation Therapy for Head and Neck Cancer
Status: COMPLETED
Conditions: Dysgeusia|Head and Neck Cancer|Oral Complications|Radiation Toxicity
Interventions: DIETARY_SUPPLEMENT: zinc sulfate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Retrospective Study Chimaera Long Nail in Adult Patient
Status: RECRUITING
Conditions: Pertrochanteric Fracture of Femur|Intertrochanteric Fracture of Femur|Subtrochanteric Fracture of Femur
Interventions: DEVICE: Chimaera Long Nail
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Validity and Reliability of the PROprioception Measurement Tool (PROMT)
Status: COMPLETED
Conditions: Child Development|Upper Motor Neurone Lesion|Cerebral Palsy|Proprioceptive Disorders
Interventions: OTHER: Proprioception measurement tool
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MCLA-128 With Trastuzumab/Chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer.
Status: COMPLETED
Conditions: Breast Cancer Metastatic
Interventions: DRUG: Zenocutuzumab|DRUG: Trastuzumab|DRUG: Vinorelbine|DRUG: Endocrine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Lymphoblastic Leukemia Therapies Informed by Genomic Analyses
Status: TERMINATED
Conditions: Leukemia, Acute Lymphoblastic
Interventions: OTHER: Acute Lymphobastic Leukemia (ALL) Treatment Options
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conventional Ultrasound Versus Remote Ultraportable ulTrasound in the Context of Viral Hepatitis
Status: NOT_YET_RECRUITING
Conditions: Hepatitis|Teleradiology
Interventions: DEVICE: TUP ultraportable US with teleradiology capacities|DEVICE: CUS conventional ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Body Fat as Determinant of Female Gonadal Dysfunction
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome|Hypothalamic Amenorrhea
Interventions: DIAGNOSTIC_TEST: Anthropometric and physical examination|DIAGNOSTIC_TEST: Indirect calorimetry, accelerometer and seven-day dietary recall|DIAGNOSTIC_TEST: Biochemical, hormonal and metabolic phenotyping|DIAGNOSTIC_TEST: Sonographic studies|DIAGNOSTIC_TEST: 24-hour Ambulatory blood pressure monitoring|PROCEDURE: Percutaneous biopsy|DIAGNOSTIC_TEST: Cardiovascular autonomic function studies|DIAGNOSTIC_TEST: Oral smear and feces specimen
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Japanese P III vs Voglibose and Placebo
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: BI 1356|DRUG: BI 1356|DRUG: voglibose placebo|DRUG: BI 1356 placebo|DRUG: voglibose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Robotic Bronchoscopy With Cone CT and Indocyanine Green to Aid Removal of Lung Lesions in Patients With Stage I Non-small Cell Lung Cancer or Lung Metastases, REPLACING Study
Status: WITHDRAWN
Conditions: Lung Non-Small Cell Carcinoma|Metastatic Malignant Neoplasm in the Lung|Stage I Lung Cancer AJCC v8
Interventions: PROCEDURE: Computed Tomography|DRUG: Indocyanine Green Solution|DEVICE: Therapeutic Bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Deep Tissue Injury Treatment With MIST Therapy Versus Standard Care: REVERSE DTI Study
Status: TERMINATED
Conditions: Wound of Skin
Interventions: DEVICE: MIST Therapy|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Female Patients With Signs of uRgE and Stress Urinary Incontinence Study of Propiverine Hydrochloride
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DRUG: Propiverine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STRETTA ,Radio Frequency Ablation (RFA) v/s Sham Therapy for the Treatment of Refractory GERD
Status: UNKNOWN
Conditions: GERD
Interventions: DEVICE: Radio Frequency Ablation (RFA) (Stretta Procedure)|PROCEDURE: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Transcranial Direct Current Stimulation on Upper Extremity of Children With Hemiparesis
Status: COMPLETED
Conditions: Cerebral Palsy Infantile
Interventions: DEVICE: Brain stimulator v3.0|OTHER: Sham Comparator: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interferon and Ribavirin Treatment in Patients With Hemoglobinopathies
Status: UNKNOWN
Conditions: Hemoglobinopathies
Interventions: DRUG: PEG-IFN alpha2a or PEG-IFN alpha2b and Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Desmoteplase in Acute Ischemic Stroke (DIAS)
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Desmoteplase|DRUG: Desmoteplase|DRUG: Desmoteplase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double-Blind, Placebo-Controlled, With PHX1149 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: PHX1149
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Application of "Heidelberg Triangle" Dissection in Pancreatoduodenectomy and Distal Pancreatectomy
Status: RECRUITING
Conditions: Pancreatoduodenectomy|Periampullary Carcinoma|Pancreatic Cancer
Interventions: PROCEDURE: TRIANGLE operation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Micafungin Versus Intravenous Itraconazole as Empirical Antifungal Therapy for Febrile Neutropenic Patients With Hematological Diseases
Status: COMPLETED
Conditions: Febrile Neutropenia|Hematological Diseases
Interventions: DRUG: Micafungin sodium|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnesium Administration in Liver Transplantation and Reperfusion Injury
Status: COMPLETED
Conditions: Living Donor Liver Transplantation|Reperfusion Injury
Interventions: DRUG: magnesium|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of a Botanical Drug Containing East Indian Sandalwood Oil (EISO) for the Treatment of Molluscum Contagiosum
Status: TERMINATED
Conditions: Molluscum Contagiosum
Interventions: DRUG: 10% East Indian sandalwood oil cream|DRUG: Placebo Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and Carboplatin Followed by Oral Capecitabine, Docetaxel and Radiation for Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Neoplasms
Interventions: DRUG: Capecitabine (Xeloda)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continues Positive Airway Pressure Treatment for Patients With Dilated Cardiomyopathy and Obstructive Sleep Apnea
Status: UNKNOWN
Conditions: Dilated Cardiomyopathy|Obstructive Sleep Apnea
Interventions: DEVICE: Continues Positive Airway Pressure (CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Study the Effect of Long Term Vitamin D Supplementation on Insulin Sensitivity
Status: COMPLETED
Conditions: Obesity|Insulin Resistance
Interventions: DRUG: Cholecalciferol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ELUVIA™ Drug-eluting Stent Versus Zilver® PTX® Stent
Status: COMPLETED
Conditions: Atherosclerosis of Native Arteries of the Extremities
Interventions: DEVICE: ELUVIA (Stent Implantation)|DEVICE: Zilver PTX (Stent Implantation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of the Additional Weight on the Reaching Behavior of Pre Term Infants With Low Birth Weight
Status: COMPLETED
Conditions: Preterm Infant|Infant Development|Low Birth Weight
Interventions: OTHER: Training with additional weight|OTHER: Training without additional weight
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: PROCEDURE: Automated recommendation at the start of the case|PROCEDURE: Automated notification at the start of surgery|PROCEDURE: Preoperative recommendations: by email|PROCEDURE: Automated notification at the end of surgery|DEVICE: Anesthesia Information Management System (AIMS)|DEVICE: Perioperative Data Warehouse (PDW)|PROCEDURE: General anesthesia|PROCEDURE: Elective surgery|DRUG: Propofol|DRUG: Sevoflurane|DRUG: Isoflurane|DRUG: Desflurane|DRUG: Scopolamine|DRUG: Droperidol|DRUG: Haloperidol|DRUG: Dexamethasone|DRUG: Promethazine|DRUG: Meclizine|DRUG: Aprepitant|DRUG: Metoclopramide|DRUG: Fentanyl|DRUG: Sufentanil|DRUG: Alfentanil|DRUG: Remifentanil|DRUG: Morphine|DRUG: Meperidine|DRUG: Hydromorphone|DRUG: Methadone|DRUG: Oxycodone|DRUG: Oxymorphone|DRUG: Hydrocodone|DRUG: Ketamine|DRUG: Ondansetron|DRUG: Granisetron|DRUG: Dolasetron mesylate|DRUG: Palonosetron|DRUG: Tropisetron|DRUG: Ramosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Gastroparesis in Cystic Fibrosis
Status: WITHDRAWN
Conditions: Gastroparesis
Interventions: DEVICE: 13^C Spirulina Platensis Gastric Emptying Breath Test (GEBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Curcumin and Yoga Therapy for Those at Risk for Alzheimer's Disease
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: DRUG: Curcumin|BEHAVIORAL: aerobic yoga|BEHAVIORAL: non aerobic yoga|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group-comparison Trial of Aripiprazole in the Treatment of Patients With Bipolar Disorder Experiencing a Manic or Mixed Episode
Status: COMPLETED
Conditions: Bipolar I Disorder
Interventions: DRUG: Aripiprazole|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine if Aquamin Modulates Inflammatory Biomarkers in the Blood of Osteoarthritis and Healthy Subjects
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: AquaCal|DIETARY_SUPPLEMENT: AquaPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Statistical Analysis Plan for the SANO-trial: Neoadjuvant Chemoradiotherapy Followed by Surgery Versus Active Surveillance for Oesophageal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophageal Cancer|Active Surveillance|Neoadjuvant Chemoradiotherapy|Surgical Oncology
Interventions: PROCEDURE: Active surveillance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of the Mindfulness-Based Stress Reduction Intervention for Black Women Living With HIV Supplement
Status: COMPLETED
Conditions: HIV Infections|Mild Cognitive Impairment
Interventions: BEHAVIORAL: Mindfulness|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Synchrony Study: Examining Music Training for Children With FASD
Status: RECRUITING
Conditions: Fetal Alcohol Spectrum Disorders
Interventions: BEHAVIORAL: Music listening|BEHAVIORAL: Piano training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Afatinib as Third- or Further-line Treatment for Patients With Stage IV Bronchial Adenocarcinoma, Harboring Wild-type EGFR, Expressing the Neurotensin - Neurotensin Receptor Complex
Status: WITHDRAWN
Conditions: SMALL CELL LUNG CARCINOMA
Interventions: DRUG: Afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extended (6-Week) Varenicline Preloading: Does it Facilitate Smoking Reduction and Cessation?
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Varenicline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Macintosh Versus GlideScope Versus C-MAC for Double Lumen Endotracheal Intubation
Status: COMPLETED
Conditions: Thoracic
Interventions: DEVICE: Intubation of the double lumen tube by Macintoch laryngoscope|DEVICE: Intubation of the double lumen tube by Glidescope videolaryngoscope|DEVICE: Intubation of the double lumen tube by C-MAC®(D) videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study Following People With Haemophilia A and B, With or Without Inhibitors, When on Usual Treatment (Explorer™6)
Status: COMPLETED
Conditions: Haemophilia A|Haemophilia A With Inhibitors|Haemophilia B|Haemophilia B With Inhibitors
Interventions: OTHER: No treatment given
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Magnesium for Peroral Endoscopic Myotomy
Status: COMPLETED
Conditions: Esophageal Spasm
Interventions: DRUG: Magnesium sulfate|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Use of Virtual Reality Mask During Blood and Skin Allergic Tests in 7 to 13 Children
Status: RECRUITING
Conditions: Virtual Reality|Children, Only|Pain, Procedural|Anxiety and Fear
Interventions: DEVICE: Virtual reality mask|OTHER: control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intravenous Milk Thistle (Silibinin-Legalon) for Hepatic Failure Induced by Amatoxin/Amanita Mushroom Poisoning
Status: TERMINATED
Conditions: Amatoxin Poisoning|Amanita Poisoning|Mushroom Poisoning|Liver Failure
Interventions: DRUG: Silibinin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Pharmacokinetics and Safety of BMS-663068 Administered in Subjects With Normal Renal Function and With Mild, Moderate, Severe and End Stage Renal Dysfunction (ESRD)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Oral BMS-663068 (pro-drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Research Study to Assess the Efficacy of Two Brushing Regimens
Status: NOT_YET_RECRUITING
Conditions: Dental Plaque|Gingivitis
Interventions: DRUG: Test Regimen|DRUG: Control Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib Plus Sintilimab in Patients With Immune Checkpoint Inhibitor Previously Treated Advanced Liver Cancer
Status: RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Sintilimab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing School Wide PBS in Middle Schools: The Foundation for Effective Prevention
Status: COMPLETED
Conditions: Substance Abuse|Mental Health
Interventions: BEHAVIORAL: Positive Behavior Supports in Middle Schools|BEHAVIORAL: Positive Behavior Supports in Middle Schools
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Endoscopy Assisted Probing Versus Simple Probing in Primary Congenital Nasolacrimal Duct Obstruction
Status: UNKNOWN
Conditions: Congenital Nasolacrimal Duct Obstruction
Interventions: PROCEDURE: Endoscopy Assisted Probing procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity and Sedentary Behavior Change; Impact on Lifestyle
Status: ACTIVE_NOT_RECRUITING
Conditions: Sedentary Lifestyle|Physical Activity
Interventions: BEHAVIORAL: Physical Activity Increase (GLB-MOD)|BEHAVIORAL: Sedentary Time Decrease (GLB-SED)|OTHER: 6-month delayed (DELAYED)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vaccine Therapy Using Melanoma Peptides for Cytotoxic T Cells and Helper T Cells in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: melanoma helper peptide vaccine|BIOLOGICAL: multi-epitope melanoma peptide vaccine|BIOLOGICAL: sargramostim|BIOLOGICAL: tetanus peptide melanoma vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics in Alzheimer's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease
Interventions: DIETARY_SUPPLEMENT: Low dose probiotics|DIETARY_SUPPLEMENT: Normal dose probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Loteprednol in Reducing Post-Intravitreal Injection Related Pain
Status: RECRUITING
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: Loteprednol Etabonate Ophthalmic Gel [Lotemax]|OTHER: Refresh Lubricant Eye Drops [Artificial Tears]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy With a Combination of Pegylated Liposomal Doxorubicin (Caelyx®) and Paclitaxel in Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Pegylated Liposomal Doxorubicin and docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydrocortisone Use After Etomidate in Intensive Care
Status: COMPLETED
Conditions: Patient Admitted in Reanimation
Interventions: DRUG: Hydrocortisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mid-term Outcomes of First MTP Arthroplasty With Primus™ FGT Implant.
Status: COMPLETED
Conditions: Hallux Limitus of Left Great Toe|Rheumatoid Arthritis|Arthritis of 1st Metatarsophalangeal Joint|Osteoarthritis|Bunion|Hallux Limitus of Right Great Toe
Interventions: DEVICE: Primus FGTI (Flexible Great toe Implant)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of an Oxymizer® During Daytime in Patients With Pulmonary Fibrosis (IPF)
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DEVICE: Oxymizer® compared to CNC|DEVICE: Oxymizer® compared to CNC|DEVICE: Oxymizer® compared to CNC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiographic and Clinical Outcomes of PureGen in Posterior Lumbar (PLIF) and Transforaminal Interbody Fusion (TLIF)
Status: TERMINATED
Conditions: Lumbar Degenerative Disc Disease
Interventions: BIOLOGICAL: PureGen Osteoprogenitor Cell Allograft
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tolerability and Acceptance of Two Oral Hydrocortisone Compounding Formulation for Pediatrics
Status: NOT_YET_RECRUITING
Conditions: Adrenal Insufficiency
Interventions: DRUG: 3D printed chewable formulation of hydrocortisone|DRUG: Oral suspension of hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thunderbeat Technology vs Standard Bipolar Electro Surgery in Laparoscopic Radical Hysterectomy and Pelvic Lymphadenectomy for Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: PROCEDURE: Thunderbeat technology|PROCEDURE: Standard bipolar electrosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Do Iron And Vitamin B12 Injections Given Together, Improve Hemoglobin In Patients On Hemodialysis?
Status: UNKNOWN
Conditions: Iron Deficiency Anemia|B12 Deficiency Anemia
Interventions: DRUG: Ferric carboxymaltose|DRUG: Hydroxycobalamin|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of AffloVest in At-Risk Respiratory Patients During COVID-19 Pandemic
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease|Chronic Cough|Covid19
Interventions: DEVICE: HCFWO|OTHER: Standard Care Plus Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Heated Intraperitoneal Chemotherapy Followed by Niraparib for Ovarian, Primary Peritoneal and Fallopian Tube Cancer
Status: RECRUITING
Conditions: Stage III Ovarian Cancer|Stage IV Ovarian Cancer|Stage III Primary Peritoneal Cancer|Stage IV Primary Peritoneal Cancer|Stage III Fallopian Tube Cancer|Stage IV Fallopian Tube Cancer
Interventions: DRUG: Cisplatin|OTHER: No treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Myocardial Protective Effect of Upper Limb Ischemic Preconditioning in Patients Undergoing Off-pump Coronary Artery Bypass Grafting
Status: UNKNOWN
Conditions: OPCABG
Interventions: OTHER: RIPC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: High Dose Rate Intracavitary Brachytherapy as the Sole Method of Radiation Therapy for Breast Carcinoma
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DEVICE: High Dose Intracavitary Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjusting Fluid Removal Based on Blood Volume in Hemodialysis: A Randomized Study
Status: COMPLETED
Conditions: Intradialytic Hypotension|End Stage Renal Failure on Dialysis
Interventions: DEVICE: BVM-UF biofeedback|DEVICE: Fresenius 5008 HD machine (Fresenius Medical Care, Bad Homburg, Germany)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Pharmacokinetics and Safety of Current Factor VIII Concentrate and Optivate® in Haemophilia A.
Status: COMPLETED
Conditions: Von Willebrand Disease
Interventions: BIOLOGICAL: Optivate® (Human Coagulation Factor VIII)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Optimal VAsopressor TitraTION in Patients 65 Years and Older
Status: ACTIVE_NOT_RECRUITING
Conditions: Vasopressors|Hypotension|Mean Arterial Pressure Targets|Usual Care
Interventions: BEHAVIORAL: MAP target 60-65 mmHg|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of PCV15 Vaccination Among PPSV23-experienced, Immunocompromised Elderly Veterans
Status: NOT_YET_RECRUITING
Conditions: Pneumococcal Vaccines|Immunosuppression
Interventions: DRUG: 15-valent pneumococcal conjugate vaccine|DRUG: 23-valent pneumococcal polysaccharide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-PD-1 Antibody Plus DEB-TACE for BCLC Stage A/B HCC
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sintilimab|DRUG: DEB-TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ranibizumab in Diabetic Vitrectomy. A Prospective, Randomised Controlled Trial of Ranibizumab Pre-treatment in Diabetic Vitrectomy - a Pilot Study
Status: COMPLETED
Conditions: Diabetic Retinopathy|Retinal Neovascularisation
Interventions: DRUG: Ranibizumab|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation of Right Atrial Strain With Pulmonary Hypertension, Right Ventricular Function And Outcome In Pediatric Patients
Status: RECRUITING
Conditions: Pulmonary Hypertension
Interventions: DIAGNOSTIC_TEST: Transthoracic and transesophageal echocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intraperitoneal Instillation of Levobupivacaine With Morphine Versus Levobupivacaine With Magnesium Sulfate for Postoperative Analgesia
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: intraperitoneal levobupivacaine and morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dexmedetomidine on Microcirculation in Septic Shock
Status: COMPLETED
Conditions: Septic Shock
Interventions: DRUG: Dexmedetomidine 0.7 Mcg/kg/h
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab Before Surgery for the Treatment of Regionally Metastatic Head and Neck Squamous Cell Cancer With an Unknown or Historic Primary Site
Status: TERMINATED
Conditions: Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck|Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck|Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8
Interventions: BIOLOGICAL: Atezolizumab|RADIATION: Radiation Therapy|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Mesothelin Antibody Drug Conjugate Anetumab Ravtansine for Mesothelin Expressing Lung Adenocarcinoma
Status: TERMINATED
Conditions: Lung Neoplasms
Interventions: DRUG: Anetumab Ravtansine|DEVICE: Blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating IBD With Inulin
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases
Interventions: DIETARY_SUPPLEMENT: Oligofructose-enriched Inulin OI|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Lidocaine in Open Lung Resection Surgery
Status: COMPLETED
Conditions: Lidocaine|Pain, Postoperative
Interventions: DRUG: Lidocaine Iv|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia With Inhibitors
Status: ACTIVE_NOT_RECRUITING
Conditions: Haemophilia A With Inhibitors|Haemophilia B With Inhibitors
Interventions: DRUG: Concizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RC18 Administered Subcutaneously to Subjects With IgA(Immunoglobulin A) Nephropathy
Status: COMPLETED
Conditions: IgA Nephropathy
Interventions: BIOLOGICAL: RC18 160mg|BIOLOGICAL: RC18 240mg|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PuraBond® and Pain Following Resection of Oral or Oropharyngeal Mucosal Lesions
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain|Hemorrhage|Hemostatics|Oropharynx|Oral Cavity
Interventions: OTHER: PuraBond
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Chronic Hip Pain by Application of Conventional Radiofrequency Thermocoagulation to the Articular Branches of the Femoral and Obturatory Nerve
Status: UNKNOWN
Conditions: Hip Pain Chronic
Interventions: PROCEDURE: Radiofrequency thermal coagulation of articular branches of femoral and obturator nerves
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Melatonin to Reduce Nocturnal Hypertension in Patients With Neurogenic Orthostatic Hypotension
Status: TERMINATED
Conditions: Hypotension, Orthostatic|Hypertension|Autonomic Nervous System Diseases
Interventions: DRUG: Yohimbine|DRUG: Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rectal Reconstruction in Treating Patients Who Are Undergoing Surgery for Rectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: PROCEDURE: 5 cm colon-J-pouch|PROCEDURE: side-to-end anastomosis|PROCEDURE: straight coloanal anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT