pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Inspiration Point-A Digital Pulmonary Rehabilitation Tool Management Interventions
Status: COMPLETED
Conditions: COPD
Interventions: OTHER: Usual Care Pulmonary Rehabilitation Program|OTHER: Pulmonary Rehabilitation Software-Based Home Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of High Dose Atorvastatin in Patients With Surgical Aortic Stenosis
Status: UNKNOWN
Conditions: Aortic Valve Stenosis|Ventricular Hypertrophy
Interventions: DRUG: Atorvastatin 80 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: LUNAR IIIb Study Comparing Rosuvastatin and Atorvastatin in Subjects With Acute Coronary Syndromes
Status: COMPLETED
Conditions: Acute Coronary Syndromes
Interventions: DRUG: rosuvastatin calcium|DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flumazenil Reversal of Oral Triazolam
Status: COMPLETED
Conditions: Dental Anxiety
Interventions: DRUG: Flumazenil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transvaginal Natural Orifice Endoscopic Surgery for Extremely Obese Patients With Early-stage Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Cancer|Extreme Obesity
Interventions: PROCEDURE: Transvaginal natural orifice endoscopic surgery for endometrial cancer staging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Opioid-Free Shoulder Arthroplasty
Status: COMPLETED
Conditions: Opioid Use|Shoulder Osteoarthritis|Avascular Necrosis|Rotator Cuff Tear|Arthritis;Inflammatory
Interventions: DRUG: Gabapentin|DRUG: Celecoxib|DRUG: toradol|DRUG: acetaminophen|DRUG: regional block|DRUG: propofol|DRUG: IV lidocaine|DRUG: rocuronium|DRUG: vecuronium|DRUG: sevoflurane|DRUG: desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of DHA Supplementation on Cognitive Performance and Growth in Chinese Children
Status: UNKNOWN
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Vitamins + DHA supplement (Vitamins A,D, E and algal oil)|DIETARY_SUPPLEMENT: Vitamins supplement (Vitamins A,D, E and corn oil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Recombinant Human Hyaluronidase in Treating Lymphedema in Patients With Cancer
Status: TERMINATED
Conditions: Lymphedema|Malignant Neoplasm
Interventions: BIOLOGICAL: recombinant human hyaluronidase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of an Aerobic Exercise Intervention on Core Symptoms, Executive Functioning, and Quality of Life in Children With Attention Deficit Hyperactivity Disorder
Status: RECRUITING
Conditions: ADHD
Interventions: BEHAVIORAL: aerobics exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sound Quality Comparisons With Different Hearing Aid Couplings and Venting Systems
Status: COMPLETED
Conditions: Hearing Loss, Sensorineural
Interventions: DEVICE: Audeo P90 hearing aid with custom earmolds using dynamic venting|DEVICE: Audeo P90 hearing aid with Open domes|DEVICE: Audeo P90 hearing aid with Vented domes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Arimoclomol in Inclusion Body Myositis (IBM)
Status: COMPLETED
Conditions: Inclusion Body Myositis
Interventions: DRUG: Arimoclomol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Mechanisms of Acquired Resistance to Panitumumab
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: BIOLOGICAL: Panitumumab|BIOLOGICAL: Ganitumab|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Loss Prevention With Zoledronic Acid or Denosumab in Critically Ill Adults
Status: RECRUITING
Conditions: Critical Illness|Osteoporosis
Interventions: DRUG: Denosumab 60 MG/ML|DRUG: Zoledronic Acid 5Mg/Bag 100Ml Inj|DRUG: Sodium Chloride 0.9% Intravenous|DRUG: Sodium Chloride 0.9% Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perceptual-Cognitive Training After a Mild Traumatic Brain Injury: Towards a Sensitive Marker for Recovery
Status: COMPLETED
Conditions: Brain Concussion|Post-Concussion Symptoms|Concussion
Interventions: OTHER: 3D-MOT Neurotracker|OTHER: Visual Attention Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study to Assess an Adapted Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Transplantation
Status: COMPLETED
Conditions: Haematological Malignancy|Acute Leukemia|Myelodysplastic Syndromes|Hemoglobinopathy in Children|Bone Marrow Aplasia|Severe Combined Immunodeficiency
Interventions: OTHER: Physical activity program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type Fibromatosis
Status: COMPLETED
Conditions: Desmoid Tumor
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glibenclamide Advantage in Treating Edema After Intracerebral Hemorrhage
Status: COMPLETED
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: Glibenclamide Tablets|OTHER: Standard management for ICH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Trial Of Maraviroc Versus Emtricitabine/Tenofovir Both With Darunavir/Ritonavir In Antiretroviral-Naive Patients Infected With CCR5 Tropic HIV 1
Status: TERMINATED
Conditions: HIV-1
Interventions: DRUG: Maraviroc|DRUG: Emtricitabine/tenofovir|DRUG: darunavir/ritonavir 800/100 mg|DRUG: placebo for emtricitabine/tenofovir|DRUG: placebo for maraviroc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Abituzumab in Combination With Cetuximab and FOLFIRI in Patients With Metastatic Colorectal Cancer.
Status: WITHDRAWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: abituzumab|COMBINATION_PRODUCT: Placebo + Cetuximab + FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Xenon Combined With Intraoperative Thoracic Epidural Analgesia
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Xenon|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Erector Spinae Plane Block vs. iPACK Block With Adductor Canal Block for Total Knee Arthroplasty
Status: RECRUITING
Conditions: Knee Osteoarthritis|Knee Pain Chronic|Knee Arthritis
Interventions: DRUG: Control Test - spinal anesthesia|DRUG: Ropivacaine 0.2% Injectable Solution ESPB|DRUG: Ropivacaine 0.2% Injectable Solution iPACK+ACB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Estimate How Much Tafamidis Created In Different Ways Can Be Measured in Blood Samples
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Tafamidis|DRUG: Tafamidis|DRUG: Tafamidis|DRUG: Tafamidis|DRUG: Tafamidis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 1B/2A Trial of NADUNOLIMAB in Combination With Azacitidine (With/Without Venetoclax) in Patients With Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML)
Status: NOT_YET_RECRUITING
Conditions: Myelodysplastic Syndrome(MDS)|Acute Myelogenous Leukemia (AML)
Interventions: DRUG: Nadunolimab|DRUG: Azacitidine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tepilta® Versus Oxetacaine, Antacids and Placebo
Status: TERMINATED
Conditions: Radiation-induced Oesophagitis
Interventions: DRUG: oxetacaine, aluminium and magnesium hydroxide|DRUG: oxetacaine|DRUG: magnesium and aluminium hydroxide|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Caffeine and Neurologic Recovery Following Surgery and General Anesthesia
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Caffeine Citrate|DRUG: Dextrose Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of an Antibody Against Zika Virus (Tyzivumab) in Humans
Status: COMPLETED
Conditions: Treatment of Acute Zika Virus Infection
Interventions: DRUG: Tyzivumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Actigraphic Measurement of a Neurosurgical Procedure
Status: COMPLETED
Conditions: Sleep Disorders|Circadian Rhythm|Pain|Rehabilitation|Mood Lability
Interventions: PROCEDURE: Re-section of a large left anterior cranial fossa meningioma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Beta2-mimetic and Central Nervous System
Status: COMPLETED
Conditions: Adrenergic Beta-2 Agonist Effect|Albuterol Effect
Interventions: DRUG: Salbutamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low-level Light Therapy on Treatment of Venous Ulcers Assesed by Nursing Outcome Classification (NOC)
Status: COMPLETED
Conditions: Venous Ulcer|Low-Level Light Therapy
Interventions: PROCEDURE: Low-level Light Therapy|COMBINATION_PRODUCT: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Consciousness by Brain-computer Interface in Severely Brain Damaged Patients
Status: COMPLETED
Conditions: Traumatic Brain Injury With Prolonged Loss of Consciousness|Stroke|Brain Hypoxia
Interventions: OTHER: Clinical evaluation of consciousness by the Coma Recovery Scale Revised (CRS-R)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Evaluation of the Utility of the ExSpiron Respiratory Variation Monitor During Upper GI Endoscopy
Status: COMPLETED
Conditions: Biliary Tract Diseases|Stomach Neoplasms|Carcinoma, Pancreatic Ductal|Barrett Esophagus
Interventions: DEVICE: ExSpiron Respiratory Variation Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Accuracy of Maxillary Obturator Bulb in Maxillectomy Defects
Status: COMPLETED
Conditions: Maxillary Obturators
Interventions: DEVICE: Maxillary Obturator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: GENETIC: fluorescence in situ hybridization|GENETIC: gene expression analysis|GENETIC: microarray analysis|GENETIC: mutation analysis|GENETIC: protein analysis|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: microscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Etidronate in Sodium Hypochlorite Versus Sodium Hypochlorite on the Intensity of Postoperative Pain
Status: UNKNOWN
Conditions: Necrotic Pulp
Interventions: COMBINATION_PRODUCT: etidronate in sodium hypochlorite|COMBINATION_PRODUCT: sodium hypochlorite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib in Treating Patients With Refractory Metastatic Cutaneous Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Melanoma|Recurrent Cutaneous Melanoma|Stage IV Cutaneous Melanoma AJCC v6 and v7
Interventions: DRUG: Ibrutinib|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacogenomic Study|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 3 of 4)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: COMBINATION_PRODUCT: PRT064445/Enoxaparin|COMBINATION_PRODUCT: Placebo/Enoxaparin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Efficacy and Safety of Enhanced Recovery After Surgery （ERAS）in Gastrointestinal Cancer
Status: COMPLETED
Conditions: Enhanced Recovery After Surgery|Gastrointestinal Cancer
Interventions: PROCEDURE: Enhanced Recovery After Surgery （ERAS）
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel-coated Balloons in Femoral Indication to Defeat Restenosis
Status: COMPLETED
Conditions: Peripheral Artery Disease
Interventions: DEVICE: Percutaneous transluminal angioplasty (PTA)|COMBINATION_PRODUCT: DCB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ripasudil 0.4% Eye Drops in Fuchs Endothelial Corneal Dystrophy
Status: UNKNOWN
Conditions: Fuchs' Endothelial Dystrophy|Fuchs Dystrophy|Corneal Endothelial Dystrophy|Corneal Endothelial Cell Loss|Cornea Guttata
Interventions: DRUG: Ripasudil eye drops|DRUG: Optive eye drops|PROCEDURE: Descemetorhexis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Individualized and Standardized Acupuncture Treatment for Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis Knee
Interventions: PROCEDURE: Standardized Acupuncture|PROCEDURE: sham acupuncture|PROCEDURE: Individualized Acupuncture|OTHER: Waiting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Application Time of 38% Silver Diamine Fluoride Solution on Arresting Dental Caries in Preschool Childre
Status: COMPLETED
Conditions: Early Childhood Caries
Interventions: OTHER: 3-second SDF application|OTHER: 5-second SDF application|OTHER: 10-second SDF application|OTHER: 15-second SDF application|OTHER: 30-second SDF application|OTHER: 45-second SDF application|OTHER: 60-second SDF application|OTHER: 120-second SDF application|OTHER: 180-second SDF application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1b/2a Study of ABI-H0731 in Patients With Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: ABI-H0731|DRUG: Placebo for ABI-H0731|DRUG: Entecavir|DRUG: Tenofovir Disoproxil Fumarate|DRUG: Pegasys
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Renal Biomarkers in AKI and COVID-19
Status: COMPLETED
Conditions: Coronavirus Infection|Covid19|SARS (Severe Acute Respiratory Syndrome)|AKI
Interventions: DIAGNOSTIC_TEST: urinary NGAL, TIMP-2, IGFBP7, IL-6, viral load and metabolomic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of DWJ1609 for Bowel Cleansing Before Colonoscopy;
Status: NOT_YET_RECRUITING
Conditions: Colonoscopy
Interventions: DRUG: DWJ1609|DRUG: DWC202304
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of the Paradise™ Renal Denervation System in Patients With Hypertension (RADIANCE-HTN DUO)
Status: RECRUITING
Conditions: Hypertension|Vascular Diseases|Cardiovascular Diseases
Interventions: DEVICE: Paradise™ (PRDS-001) Renal Denervation Ultrasound System|DEVICE: Renal Angiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Outcomes of Cannabinoid (CBD) Roll-on Topical Stick in Primary Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Pain, Joint|Pain, Postoperative|Total Knee Arthroplasty
Interventions: DRUG: CBD|DRUG: Mineral Oil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of Photobiomodulation (PBM) Therapy in People With Oral Graft-Versus-Host Disease (GVHD) After Stem Cell Transplant
Status: RECRUITING
Conditions: Graft-Versus-Host Disease|GVHD|Undefined
Interventions: DEVICE: Photobiomodulation Therapy|OTHER: Placebo sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Musculoskeletal Pain and Its Impact on Quality of Life and Functional Exercise Capacity in Patients With Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: OTHER: Evaluation of musculoskeletal pain prevalence|OTHER: Evaluation of quality of life|OTHER: Evaluation of functional exercise capacity|OTHER: Evaluation of physical activity level
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Selinexor for Treatment of Light Chain Amyloidosis With Relapsed/Refractory Disease
Status: WITHDRAWN
Conditions: Amyloid|Amyloidosis|AL Amyloidosis
Interventions: DRUG: Selinexor|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemoprevention of Cancer in the Lower Female Genital Tract: The Antineoplastic Activity of the Fungicide Ciclopirox.
Status: WITHDRAWN
Conditions: Vulvar Cancer
Interventions: DRUG: Ciclopirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: TAE and MWA Combination Therapy in Early-stage Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma|Hepatoma|Liver Cancer, Adult|Liver Cell Carcinoma|Liver Cell Carcinoma, Adult
Interventions: DEVICE: Transarterial embolization|PROCEDURE: Microwave Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of a Silicone Hydrogel Contact Lens Following Six Nights of Extended Wear
Status: COMPLETED
Conditions: Refractive Errors
Interventions: DEVICE: LID011121 contact lens|DEVICE: Comfilcon A contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ST- Depression on Electrocardiogram During Caesarean Section in Regional Anaesthesia in Women With Preeclampsia
Status: COMPLETED
Conditions: Preeclampsia
Interventions: DRUG: oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Evaluation of Deposits on Contact Lenses Worn Extended Wear
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: balafilcon A contact lens (PureVision)|DEVICE: etafilcon A contact lens (Acuvue2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: The Impact of Lorazepam on Cognition in APOE e4 Carriers
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: lorazepam|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Renal Denervation in Patients With Heart Failure With Normal LV Ejection Fraction
Status: UNKNOWN
Conditions: Heart Failure, Diastolic|Hypertension
Interventions: PROCEDURE: Renal denervation + medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Integrative Medicine at Home (IM@HOME) Program in People With Cancer
Status: RECRUITING
Conditions: Head and Neck Cancer|Head and Neck Tumor|Thoracic Tumor|Thoracic Cancer|Gynecologic Cancer|Gynecologic Tumor|Melanoma|Ovarian Cancer
Interventions: BEHAVIORAL: IM@Home|BEHAVIORAL: Enhanced usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Timing Progesterone Luteal Support on Embryo Transfer
Status: COMPLETED
Conditions: Progesterone Luteal Support in ICSI|Embryo Transfer
Interventions: DRUG: Progesterone 100 IM/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Systemic Pharmacokinetics of AGN-232411 in Healthy Participants and Participants With Dry Eye
Status: COMPLETED
Conditions: Healthy Volunteers|Dry Eye Syndromes
Interventions: DRUG: AGN-232411|DRUG: AGN-232411 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib/II Clinical Trial of M701 in the Treatment of Malignant Pleural Effusions Caused by NSCLC
Status: NOT_YET_RECRUITING
Conditions: Malignant Pleural Effusions|NSCLC Stage IV
Interventions: DRUG: M701 pleural infusion|PROCEDURE: Pleural drainage|DRUG: Cisplatin pleural infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Hemostatic Matrix and Bipolar Coagulation in Surgical Treatment of Endometriomas
Status: COMPLETED
Conditions: Ovarian Reserve|Endometrioma
Interventions: PROCEDURE: Bipolar electrocautery for ovarian hemostasis|PROCEDURE: hemostatic matrix (FloSeal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation of the Temporal Cortex in Survivors of Childhood Acute Lymphoblastic Leukemia (ALL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Transcranial Direct Current Stimulation|Executive Dysfunction
Interventions: DEVICE: Anodal tDCS treatment|DEVICE: Cathodal tDCS treatment|DEVICE: Sham treatment|OTHER: NIH Toolbox List Sorting Working Memory Test|OTHER: NIH Toolbox Flanker Inhibitory Control and Attention Test|OTHER: Grooved Peg Board Test|OTHER: Buschke Selective Reminding Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DISulfiram for COvid-19 (DISCO) Trial
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: Disulfiram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Microbiota in Kidney Donation and Transplantation
Status: RECRUITING
Conditions: Kidney Diseases|Kidney Transplant Failure and Rejection|Urinary Tract Infections
Interventions: OTHER: Pre-operative assessment - blood, urine, & faecal sample|OTHER: Post-operative day 3 assessment - blood, urine, & faecal sample|OTHER: Post-operative week 4-6 assessment - blood, urine, & faecal sample|OTHER: Post-operative 3 month assessment - blood, urine, & faecal sample|OTHER: Pre-operative 6 month assessment - blood, urine, & faecal sample|OTHER: Post-operative month 12 recipient assessment - blood, urine, & faecal sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A 26-week Trial Comparing Efficacy and Safety of Insulin Degludec/Insulin Aspart BID and Insulin Degludec OD Plus Insulin Aspart in Subjects With Type 2 Diabetes Mellitus Treated With Basal Insulin in Need of Treatment Intensification With Mealtime Insulin
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/insulin aspart|DRUG: insulin degludec|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Pharmacokinetics, Safety, and Tolerability of BMT101 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Hypertrophic Scar
Interventions: DRUG: BMT101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Danish ICD-study in Patients With Coronary Artery Disease Resuscitated From Ventricular Fibrillation
Status: RECRUITING
Conditions: Coronary Artery Disease|Acute Myocardial Infarction|Ventricular Fibrillation|Ventricular Tachycardia, Sustained|Out-Of-Hospital Cardiac Arrest
Interventions: DEVICE: Implantable cardioverter defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Establishment and Application of Early Postoperative Activity Plan for Patients After Hemi-laminectomy for Lumbar Spinal Tumor Resection
Status: UNKNOWN
Conditions: Tumor of Spinal Cord
Interventions: OTHER: Postoperative rehabilitation nursing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Impact of Community-based Wellness Programs on The Triple Aim
Status: RECRUITING
Conditions: Spina Bifida|Cerebral Palsy|Spinal Cord Injury|Traumatic Brain Injury
Interventions: OTHER: Wellness Programs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Surveillance Tool to Screen for Unmet Palliative Needs Among Patients in the Final Year of Life
Status: ENROLLING_BY_INVITATION
Conditions: Palliative Therapy|Implementation Science|Screening|Terminal Care
Interventions: OTHER: modified Hospital One-year Mortality Risk (mHOMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Gait Perturbations to Improve Balance Post-stroke
Status: COMPLETED
Conditions: Hemiparesis;Poststroke/CVA
Interventions: DEVICE: Gait training with perturbations|DEVICE: Gait training without perturbation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Preventive Education on Reducing Urinary Bisphenol-A Levels in Adolescents
Status: COMPLETED
Conditions: Adolescent Behavior|Bisphenol A|Urine
Interventions: BEHAVIORAL: Plastic-free diet program|BEHAVIORAL: Plastic-free diet education program|BEHAVIORAL: BPA exposure feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 24 Week Efficacy and Safety Study of Empagliflozin (BI 10773) in Hypertensive Black/African American Patients With Type 2 Diabetes Mellitus and Hypertension
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Hypertension
Interventions: DRUG: Empagliflozin low dose|DRUG: placebo|DRUG: Empagliflozin high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Randomized Controlled Study of Pulse Magnetotherapy Combined Medication in Anxiety Combined With Insomnia
Status: RECRUITING
Conditions: Anxiety Disorder|Insomnia
Interventions: DEVICE: Pulse magnetic therapy|DRUG: Selective serotonin reuptake inhibitors （SSRI）|DEVICE: Shame magnetic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Premedication by Clonidine Intranasal in Pediatric Surgery
Status: UNKNOWN
Conditions: Child Preschool
Interventions: DRUG: Clonidine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Immunogenicity of an Oral HIV Vaccine in Healthy, HIV-uninfected Adults
Status: TERMINATED
Conditions: Healthy Volunteer|HIV Vaccine
Interventions: BIOLOGICAL: Ad4-mgag|BIOLOGICAL: Ad4-EnvC150|OTHER: Placebo Comparator|BIOLOGICAL: AIDSVAX B/E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety & Effectiveness on Vascular Structure and Function of ACZ885 in Atherosclerosis and Either T2DM or IGT Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Atherosclerosis|Prediabetic State
Interventions: DRUG: ACZ885|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imatinib Mesylate in Treating Patients With Locally Recurrent or Metastatic Dermatofibrosarcoma Protuberans
Status: COMPLETED
Conditions: Adult Fibrosarcoma|Dermatofibrosarcoma Protuberans|Recurrent Adult Soft Tissue Sarcoma|Stage IV Adult Soft Tissue Sarcoma
Interventions: DRUG: imatinib mesylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Rate of En-masse Retraction in Orthodontic Patients With Maxillary Protrusion
Status: COMPLETED
Conditions: Bimaxillary Protrusion
Interventions: PROCEDURE: Power chain and Crimpable hook for En-Masse Retraction|PROCEDURE: T- Loop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Somatuline Depot (Lanreotide) Injection to Treat Carcinoid Syndrome
Status: COMPLETED
Conditions: Carcinoid Syndrome
Interventions: DRUG: Lanreotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Hip Strengthening on Dynamic Knee Stability, Disability and Gait in Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: OTHER: hip strengthening|OTHER: quadriceps strengthening, stretch hamstring,cuff muscles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using SystemCHANGE™ to Enhance Medication Adherence in Older Adult Stroke Survivors
Status: COMPLETED
Conditions: Stroke, Ischemic
Interventions: BEHAVIORAL: SystemCHANGE™|BEHAVIORAL: Attention-Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: An Efficacy and Safety Study of INM-176 for the Treatment of Patients With Alzheimer Type Dementia
Status: COMPLETED
Conditions: Alzheimer Type Dementia
Interventions: DRUG: Aricept|DRUG: INM-176
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Relief After Corneal Collagen Cross-Linking
Status: NOT_YET_RECRUITING
Conditions: Provide Evidence-based Recommendations for Clinicians to Optimize Pain Control After CXL
Interventions: DRUG: Gabapentin|DRUG: Targin|DRUG: NSAID|DRUG: Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prospective Evaluation of Open Irrigated Ablation Catheters With High Resolution Mapping to Treat Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: Boston Scientific Open Irrigated Ablation Catheters
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CHOP/Rituximab Followed by Maintenance PEG Intron in Treatment of Indolent/Follicular Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkins Lymphoma
Interventions: DRUG: CHOP/Rituximab|DRUG: PEG INTRON
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial on Use of Coloshield in Transanal and Anal Surgery
Status: UNKNOWN
Conditions: Fistula-in-ano|Rectal Polyp|Rectal Adenoma|Hemorrhoids|Anal Fissure
Interventions: DEVICE: Coloshield|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Oncobax®-AK in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Carcinoma, Renal Cell|Carcinoma, Non-Small-Cell Lung
Interventions: OTHER: Live Bacterial Product - Akkermansia muciniphila
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Steroids and Cross-linking for Ulcer Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Keratitis Bacterial
Interventions: DRUG: Moxifloxacin Ophthalmic|DRUG: Difluprednate Ophthalmic|DRUG: Riboflavin Ophthalmic|OTHER: Topical Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Ovarian Function Damage by a GnRH Analogue During Chemotherapy in Hodgkin Lymphoma Patients
Status: COMPLETED
Conditions: Hodgkin Lymphoma|Hodgkin Disease
Interventions: DRUG: triptorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does the Order in Which Vaccines Are Administered Affect Pain Response?
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Pentacel (DPTaP+Hib)|DRUG: Prevnar (conjugated pneumococcal vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evidence-based Intervention for Improved Head Impact Safety in Youth Football - Aim 1 and Aim 3
Status: COMPLETED
Conditions: Head Injury|Sport Injury
Interventions: BEHAVIORAL: On-field activity group - Aim 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing the Effect of Different Intracanal Dressing on Failed Root Canal Treated Cases on Periapical Healing
Status: ACTIVE_NOT_RECRUITING
Conditions: Periapical Disease
Interventions: DRUG: nanocurcumin gel|DRUG: Curcumin Gel|DRUG: Ciprofloxacin 500 mg +ibuprofen 400mg|DRUG: Metapaste [calcium hydroxide paste (control group)]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose Study of the Effect of Formoterol Fumarate in Combination With Mometasone Furoate Inhaled Via a Pressurized Metered Dose Inhaler (pMDI) in Children Aged 5-11 Years Old With Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Mometasone furoate/formoterol fumarate (MFF)|DRUG: Formoterol fumarate 12 μg pMDI (F12M)|DRUG: Formoterol fumarate 12 μg DPI (F12D)|DRUG: Placebo to F12D|DRUG: Placebo to F12M/MFF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: iTBS Can Increase Frontal Dopamine Release in PET Dopamine Imaging.
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DEVICE: Theta burst stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Abiraterone Acetate Combined With Dutasteride for Metastatic Castrate Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Abiraterone acetate|DRUG: Dutasteride|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: International Rapid-onset Obesity With Hypothalamic Dysfunction, Hypoventilation & Autonomic Dysregulation (ROHHAD) Registry
Status: RECRUITING
Conditions: ROHHAD|Rapid-Onset Obesity With Hypothalamic Dysfunction, Hypoventilation & Autonomic Dysregulation
Interventions: GENETIC: ROHHAD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Examining the Effects of Vivo on Physical Function and Glycemic Level in Sedentary Older With Prediabetes.
Status: RECRUITING
Conditions: PreDiabetes|Older Adult|Muscle Loss|Muscle Weakness
Interventions: BEHAVIORAL: Vivo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Chemoradiation in Combination With Tislelizumab as First Line Treatment in Participants With Advanced Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: RADIATION: Intensity-modulated radiotherapy (IMRT)|DRUG: Tislelizumab|DRUG: Cisplatin|DRUG: Nab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of Porous Silica in Men
Status: COMPLETED
Conditions: Safety Issues
Interventions: DIETARY_SUPPLEMENT: Porous silica|DIETARY_SUPPLEMENT: Placebo (microcrystalline cellulose)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Acupuncture as an Adjunctive Therapy to the Pharmacological Treatment in Patients With Chronic Pain in Osteoarthritis of the Knee: a Three Armed Randomized Placebo Controlled Trial
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: FERINJECT for Correction of Anaemia in IBD Patients, FER-IBD-COR
Status: COMPLETED
Conditions: Inflammatory Bowel Disease|Anemia|Iron Deficiency|Iron-Deficiency Anemia|Crohn's Disease|Ulcerative Colitis
Interventions: DRUG: Ferric carboxymaltose|DRUG: Iron Sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Cervical Conization for Persistent Infection or Integration of HPV
Status: NOT_YET_RECRUITING
Conditions: Human Papilloma Virus Infection|Human Papilloma Virus Integration|Cervical Intraepithelial Neoplasia|Cervical Cancer|Cervical Conization
Interventions: PROCEDURE: diagnostic cervical conization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Exploration the Mechanism of Ba-Duan-Jin in the Treatment of Fibromyalgia Based on Brain-gut Axis
Status: RECRUITING
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: Ba-Duan-Jin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II Trial of Tirelizumab Combined With R2-ICE Regimen in the Treatment of rrDLBCL/HGBL
Status: UNKNOWN
Conditions: Age Range ≥16 Years, Gender Unlimited|Histopathology Confirmed Diffuse Large B-cell Lymphoma or High-grade B-cell Lymphoma|Received Prior First-line Chemotherapy for DLBCL or HGBL, Failed to Reach CR for Four Cycles, or Relapsed|At Least One Positive Lesion According to the 2014 Lugano Criteria for Hodgkin's and Non-Hodgkin's Lymphoma|ECOG Physical Status Score is 0-3|The Researchers Judged That Life Expectancy Was at Least Three Months|Understand and Voluntarily Sign Written Informed Consent
Interventions: DRUG: TR2-ICE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the "Pupillary Pain Index" in Neurological Prognosis After Cardiac Arrest
Status: UNKNOWN
Conditions: Cardiac Arrest|Post-Anoxic Coma|Anoxic Brain Injury
Interventions: DIAGNOSTIC_TEST: Pupillary pain index (PPI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial of TQC3721 Suspension for Inhalation
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: TQC3721 suspension for inhalation|DRUG: TQC3721 suspension placebo for inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple-ascending-dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Pomalidomide (CC-4047) in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pomalidomide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Long-term Outcomes of Surgical and Nonsurgical Management of Sciatica Secondary to a Lumbar Disc Herniation or Spinal Stenosis
Status: COMPLETED
Conditions: Lumbar Disc Herniation|Lumbar Spinal Stenosis
Interventions: PROCEDURE: Low back pain surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of the Safety of Adalimumab in Rheumatoid Arthritis Patients Showing Rapid Progression of Structural Damage of the Joints, Who Have no Prior History of Treatment With Disease-modifying Anti-rheumatic Drugs or Biological Agents
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BP Limb Length of 60cm vs 100cm in Roux-en-Y Gastric Bypass
Status: UNKNOWN
Conditions: Osteopenia
Interventions: PROCEDURE: biliopancreatic limb length of 60cm.|PROCEDURE: biliopancreatic limb length of 100cm.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Mogamulizumab + MEDI4736 (Durvalumab) and Mogamulizumab + Tremelimumab in Subjects w/ Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: BIOLOGICAL: mogamulizumab|BIOLOGICAL: MEDI4736 (Durvalumab)|BIOLOGICAL: tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement of the Performance and Safety of RTR+Membrane in Guided Tissue Regeneration (GTR) in Dental Surgical Procedures
Status: RECRUITING
Conditions: Guided Bone Regeneration
Interventions: PROCEDURE: Preserving alveolar bone volume after tooth extraction|PROCEDURE: Alveolar crest reconstruction|PROCEDURE: Covering bone defects during immediate implant placement.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nicotine Patch as an Analgesic Adjuvant After Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: nicotine patch|DRUG: nicotine patch|DRUG: placebo|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT