pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety of Curosurf® in Patients Invasively Ventilated for Severe Bronchiolitis Under 12 Months of Age
Status: TERMINATED
Conditions: Bronchiolitis, Viral
Interventions: DRUG: Curosurf 80Mg/Ml Intratracheal Suspension|OTHER: Ambient Air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AlloLife - Life After Transplantation
Status: NOT_YET_RECRUITING
Conditions: Survivorship|Stem Cell Transplant Complications
Interventions: COMBINATION_PRODUCT: Technology supported, coordinated survivorship care using wearable devices, supportive patient-apps and cardio-oncology physician apps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hybrid Trial of Brief Cognitive-Behavioral Therapy for Health Anxiety in Primary Care
Status: ENROLLING_BY_INVITATION
Conditions: Illness Anxiety Disorder|Somatic Symptom Disorder|Health Anxiety
Interventions: BEHAVIORAL: Brief Cognitive-Behavioral Therapy for Health Anxiety|BEHAVIORAL: Referral to mental health provider
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Zevalin Versus Observation in Participants at Least 60 Years Old With Newly Diagnosed Diffuse Large B-cell Lymphoma in Positron Emission Tomography (PET)-Negative Complete Remission After Rituximab-Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) or R-CHOP-like Therapy
Status: TERMINATED
Conditions: Diffuse Large B-cell Lymphoma|Follicle Center Lymphoma
Interventions: DRUG: Zevalin|DRUG: Y-90-Zevalin|DRUG: Rituximab|DRUG: In-111 Zevalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Clinical Efficacy of Low-dose Ionizing Radiation in the Treatment of Osteoarthritis
Status: RECRUITING
Conditions: Arthrosis|Osteoarthritis
Interventions: RADIATION: low dose radiotherapy (0.5 Gy)|RADIATION: mock radiation treatment|RADIATION: low dose radiotherapy (1.0 Gy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of TAK-831 in Healthy Adult Asian Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-831|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Combination Chemotherapy With Ketoconazole in Treating Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Doxorubicin Hydrochloride|DRUG: Estramustine phosphate sodium|DRUG: Etoposide|DRUG: Ketoconazole|DRUG: Paclitaxel|DRUG: Vinblastine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PENG and LFCN Block Versus FIC Block for Multimodal Analgesia After Total Hip Replacement Surgery: a Retrospective Analysis Focused on Movement (Retro-PvF)
Status: NOT_YET_RECRUITING
Conditions: Regional Anesthesia Block|Regional Anesthesia|Total Hip Replacement Surgery|Total Hip Arthroplasty \(THA\)
Interventions: PROCEDURE: PENG + LFCN block|PROCEDURE: FIC block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HPV Message Testing and Social Media Campaign
Status: COMPLETED
Conditions: Vaccine|Human Papilloma Virus
Interventions: OTHER: Social Media Message about HPV and HPV vaccine|OTHER: Social media message about risk of electronic cigarettes.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pioglitazone Add-on Study in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Comparator: Sitagliptin|DRUG: Comparator: Placebo|DRUG: Comparator: Pioglitazone|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Effectiveness of Levofloxacin Compared With Lomefloxacin in the Treatment of Complicated Urinary Tract Infections
Status: COMPLETED
Conditions: Urinary Tract Infections|Bacterial Infections|Bacteriuria|Urologic Diseases
Interventions: DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-intensity Aquatic Exercise for Adults With Rheumatic Diseases
Status: COMPLETED
Conditions: Rheumatic Diseases
Interventions: OTHER: Group A: High intensity exercise training|OTHER: Group B: moderate intensity exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of CM-AT in Children With Autism With All Levels of FCT (The Blum Study)
Status: COMPLETED
Conditions: Autism
Interventions: DRUG: CM-AT|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Iressa in Patients With Relapsed or Refractory Acute Myelogenous Leukemia
Status: COMPLETED
Conditions: Myelogenous Leukemia, Acute
Interventions: DRUG: gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fondaparinux 1,5 mg for the Prevention of Venous Thromboembolism (VTE) in Medical Patients With Renal Insufficiency
Status: TERMINATED
Conditions: Medical Patients|Renal Insufficiency
Interventions: DRUG: fondaparinux
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Controlled Trial of Autologous Platelet Gel Treatment in Diabetic Foot Ulcers
Status: WITHDRAWN
Conditions: Diabetic Foot Ulcer
Interventions: PROCEDURE: Autologous Platelet Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Operational Feasibility of Appropriate Radical Cure of Plasmodium Vivax With Tafenoquine or Primaquine After Quantitative G6PD Testing in Brazil
Status: ACTIVE_NOT_RECRUITING
Conditions: Malaria, Vivax|G6PD Deficiency
Interventions: DRUG: Tafenoquine|DRUG: Primaquine|DRUG: Primaquine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Acute Migraine Factorial Study
Status: COMPLETED
Conditions: Migraine With or Without Aura
Interventions: DRUG: Naltrexone and Acetaminophen|DRUG: Naltrexone and Acetaminophen-High Dose|DRUG: Naltrexone Alone (regular dose)|DRUG: Acetaminophen Alone|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Optimization by Pharmacokinetic/Pharmacodynamic of Antibiotics to Improve Clinical Outcome of Carbapenem Resistant Klebsiella Pneumoniae Bloodstream Infections in Critically Ill Patients at Phramongkutklao Hospital
Status: RECRUITING
Conditions: Carbapenem Resistant Klebsiella Pneumoniae
Interventions: DRUG: Dose-adjustment by PKPD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Evaluate the Use of C1 Esterase Inhibitor (Human) in Patients With Acute Antibody-Mediated Rejection
Status: COMPLETED
Conditions: Graft Rejection
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: C1 Esterase Inhibitor (Human)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Elastographic Improvement of Vaginal Atrophy Treated by Erbium Yag Laser
Status: RECRUITING
Conditions: Vaginal Atrophy|Dyspareunia|Laser|Genitourinary Syndrome of Menopause (GSM)
Interventions: DEVICE: Fotona Dynamis Er:YAG Laser System|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 12-Week Study of Pristiq (Desvenlafaxine) Social Anxiety Disorder
Status: COMPLETED
Conditions: Social Anxiety Disorder
Interventions: DRUG: Pristiq|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Plasma Exchange, Rituximab and IV Ig for Severe Acute Exacerbation of IPF Admitted in ICU
Status: UNKNOWN
Conditions: Exacerbation of Idiopathic Pulmonary Fibrosis
Interventions: OTHER: Therapeutic plasma exchanges|OTHER: Conventional treatment of AE-IPF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Prophylactic Antiviral Efficacy in Patients Undergoing Chemotherapy: Entecavir Versus Lamivudine
Status: COMPLETED
Conditions: Malignancy|Hepatitis B
Interventions: DRUG: Entecavir|DRUG: Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Snack Types on Acute Glucose and Insulin Response
Status: RECRUITING
Conditions: Satiety
Interventions: OTHER: Pretzels|OTHER: Brazil nuts|OTHER: Potato chips|OTHER: Mixed nuts|OTHER: White bread|OTHER: Dried mango|OTHER: Mango fruit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Drainage in Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Acute Cholecystitis|Empyema of Gallbladder|Abscess of Gallbladder
Interventions: PROCEDURE: Laparoscopic cholecystectomy with drain insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Hippocampal Plasticity of Young Adults With Childhood Adversity
Status: COMPLETED
Conditions: Depression|Anxiety
Interventions: BEHAVIORAL: Stress Management Skill Building Program A|BEHAVIORAL: Stress Management Skill Building Program B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nonoperative Treatment of Dorsally Dislocated Distal Radius Fractures in Adults With an Individualized 3D Printed Brace.
Status: COMPLETED
Conditions: Dorsal Displacement
Interventions: DEVICE: Distal radius fracture brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Efficacy of Myofascial Induction as a Manual Therapy Technique in Patients With Anxiety
Status: COMPLETED
Conditions: Anxiety
Interventions: OTHER: Myofascial treatment|OTHER: Sham myofascial treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Biological Effects and Pharmacokinetics of BIIL 284 BS in Healthy Males
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIIL 284 oral solution|DRUG: BIIL 284 wetability improved formulation (WIF) tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Feasibility of Microwave Ablation Using Two Channel Microwave Generator and Two Antennas for Small Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: Microwave ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Aerobic Exercise on Metabolic Syndrome, Neurocognition and Empowerment in Individuals With Mental Disorders
Status: UNKNOWN
Conditions: Metabolic Syndrome|Mental Disorders
Interventions: BEHAVIORAL: Physical activity program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: EASE-SOT Pilot Study
Status: NOT_YET_RECRUITING
Conditions: Transplant;Failure,Kidney|Transplant; Failure, Heart|Transplant; Failure, Liver|Transplant; Failure, Pancreas|Transplant; Failure, Lung(S)
Interventions: OTHER: EASE-SOT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Study of Capacity-oriented Intervention to Promote Food Security and Diet Quality Among Hispanics/Latinos
Status: NOT_YET_RECRUITING
Conditions: Nutrition, Healthy|Knowledge, Attitudes, Practice|Self Efficacy
Interventions: BEHAVIORAL: Multi-level behavior-change intervention to strengthen food- and diet-related capital to promote food security and diet quality among low-income Hispanic/Latino adults
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The High Initial Dose of Monitored Vitamin D Supplementation in Preterm Infants.
Status: NOT_YET_RECRUITING
Conditions: Vitamin D Deficiency|Osteopenia of Prematurity|Nephrolithiasis|Metabolic Bone Disease|Late-Onset Neonatal Sepsis
Interventions: DIETARY_SUPPLEMENT: cholecalciferol/ Devikap|DIETARY_SUPPLEMENT: cholecalciferol/ Devikap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 1/2, Open-label, Dose-escalation Study of IONIS-STAT3Rx, Administered to Patients With Advanced Cancers
Status: COMPLETED
Conditions: Advanced Cancers|DLBCL|Lymphoma
Interventions: DRUG: IONIS-STAT3Rx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of GCF And Salivary Ferritin, ALP And MMP-8 Levels of Individuals With Different Periodontal Diseases
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: DIAGNOSTIC_TEST: GCF and saliva obtaining
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clofazimine- and Rifapentine-Containing Treatment Shortening Regimens in Drug-Susceptible Tuberculosis: The CLO-FAST Study
Status: COMPLETED
Conditions: HIV|Tuberculosis
Interventions: DRUG: Clofazimine (CFZ)|DRUG: Rifapentine (RPT)|DRUG: Isoniazid (INH)|DRUG: Pyrazinamide (PZA)|DRUG: Ethambutol (EMB)|DRUG: Rifampicin (RIF)|DIETARY_SUPPLEMENT: Pyridoxine (vitamin B6)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetes Prevention Program Feasibility Study of Breastfeeding
Status: COMPLETED
Conditions: Pregnancy|Overweight and Obesity
Interventions: BEHAVIORAL: Diabetes Prevention Program|BEHAVIORAL: Breastfeeding Education|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-Up Care With or Without CEA Assessments in Patients Who Have Undergone Surgery for Stage II or Stage III Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: PROCEDURE: Standard Monitoring CEA|PROCEDURE: Intensive Monitoring CEA|PROCEDURE: Standard Monitoring Imagery|PROCEDURE: Intensive Monitoring Imagery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fasted Bioavailability Study of Cilostazol Tablets, 50mg
Status: COMPLETED
Conditions: Therapeutic Equivalency, Healthy
Interventions: DRUG: Cilostazol 50 mg Tablets|DRUG: Cilostazol (Pletal®) 50 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Live Video Mind-body Treatment to Prevent Persistent Symptoms Following mTBI
Status: ACTIVE_NOT_RECRUITING
Conditions: MTBI - Mild Traumatic Brain Injury|Anxiety
Interventions: BEHAVIORAL: TOR-C 1|BEHAVIORAL: TOR-C 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Secukinumab in Chinese Subjects With Active PsA Compared to Placebo.
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: AIN457|OTHER: Secukinumab Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of an Acceptance-based Medication Adherence Therapy for Recent-onset Psychosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Early Psychosis|Psychotic Disorders
Interventions: BEHAVIORAL: AIM_AT|BEHAVIORAL: CPG|BEHAVIORAL: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluating Trifluridine/Tipiracil Based Chemoradiation in Locally Advanced Rectal Cancer - The Phase I/II TARC Trial
Status: TERMINATED
Conditions: Locally Advanced Rectal Cancer
Interventions: COMBINATION_PRODUCT: Trifluridine/tipiracil chemoradiation|COMBINATION_PRODUCT: Capecitabine based chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cataract and AMD in a Trial of a Multivitamin and Cocoa Extract
Status: UNKNOWN
Conditions: Cataract|Age Related Macular Degeneration
Interventions: DIETARY_SUPPLEMENT: Cocoa extract|DIETARY_SUPPLEMENT: Multivitamin|DIETARY_SUPPLEMENT: Cocoa extract placebo|DIETARY_SUPPLEMENT: Multivitamin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of DC Vaccination Against Glioblastoma
Status: UNKNOWN
Conditions: Glioma|Glioblastoma Multiforme|Neoplasms
Interventions: PROCEDURE: Surgery|DRUG: Chemotherapy|RADIATION: Radiotherapy|BIOLOGICAL: DC vaccination|DRUG: blank placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Essential Amino Acids and High Intensity Interval Training
Status: COMPLETED
Conditions: Cardiovascular Risk Factor|Obesity
Interventions: OTHER: High Intensity Interval Training|DIETARY_SUPPLEMENT: Essential Amino Acid|OTHER: High intensity interval training and essential amino acid supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Early Low Dose Steroid Therapy of Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Acute Lung Injury|Postoperative Complications
Interventions: DRUG: Methylprednisolone sodium succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anterior Ethmoidal Nerve Block in Prevention of Postoperative Agitation
Status: COMPLETED
Conditions: Postoperative Agitation: Impaired Awareness, Abnormal Cognitive Function, Confusion, and Verbal and Physical Agitation During Recovery From General Anesthesia|Deviated Nasal Septum|Chronic Rhinosinusitis (Diagnosis)|Nasal Polyps
Interventions: DRUG: Bupivacaine-epinephrine|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma
Status: ACTIVE_NOT_RECRUITING
Conditions: 1p/19q Co-deletion|Anaplastic Astrocytoma|Diffuse Astrocytoma|Glioma|IDH1 Gene Mutation|IDH2 Gene Mutation|Oligoastrocytoma|Oligodendroglioma|WHO Grade III Glioma
Interventions: RADIATION: IMRT (Intensity-Modulated Radiation Therapy)|RADIATION: Proton Beam Radiation Therapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1, First in Human Study to Investigate the Safety and Tolerability of PA401
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: PA401|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Circular Stapler-assisted Colostomy vs Hand-stitching Colostomy of Colorectal Cancer Patients
Status: TERMINATED
Conditions: Colorectal Carcinoma
Interventions: PROCEDURE: circular stapler-assisted colostomy|PROCEDURE: conventional hand-stitching colostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance and Accuracy of Healing Abutment With Scan Peg for Single Posterior Implant-supported Restorations
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Implants, Single-Tooth
Interventions: OTHER: Healing abutment with scan peg (Neoss implant system, Harrogate, England)|OTHER: Customized healing abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adipose-Derived Stromal Cells (ASC's) for Pressure Ulcers
Status: ENROLLING_BY_INVITATION
Conditions: Pressure Ulcer
Interventions: BIOLOGICAL: Adipose-derived stromal cells|DRUG: Adipose-derived stromal cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acute Resistance Exercise on Inhibitory Control
Status: UNKNOWN
Conditions: Exercise|Cognitive Function
Interventions: BEHAVIORAL: low-volume moderate-intensity group|BEHAVIORAL: moderate-volume moderate-intensity group|BEHAVIORAL: high-volume moderate-intensity group|BEHAVIORAL: moderate-volume low-intensity group|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Surgical Thoracic Outlet Decompression for Neurogenic Thoracic Outlet Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Neurogenic Thoracic Outlet Syndrome
Interventions: PROCEDURE: Thoracic outlet decompression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Attenuation of the Hemodynamic Response to Double-lumen Endotracheal Intubation With Nebulized Lidocaine
Status: NOT_YET_RECRUITING
Conditions: Lung Neoplasms
Interventions: DRUG: Lidocaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Exploratory Clinical Trials for the Feasibility, Primary Safety and Efficacy of Foldable Capsular Vitreous Body
Status: COMPLETED
Conditions: Retinal Detachment
Interventions: DEVICE: foldable capsular vitreous body(FCVB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intercalated Administration of PamCis With Gefitinib or Placebo as First Line Lung Adenocarcinoma in Never Smokers
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer|Adenocarcinoma
Interventions: DRUG: Gefitinib|DRUG: Placebo|DRUG: Pemetrexed plusCIsplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Remifentanil on the Bispectral Index in Women Undergoing Caesarean Delivery Under General Anaesthesia
Status: COMPLETED
Conditions: Intraoperative Awareness
Interventions: DRUG: remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Unilateral TAP Block vs Trocar Insertion Sites Infiltration Anesthesia in Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Biliary Disease
Interventions: DRUG: Transversus abdominis plane block|DRUG: local infiltration anesthesia|DRUG: Intravenous patient controlled analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Incubator Weaning of Moderately Preterm Infants
Status: COMPLETED
Conditions: Infant, Newborn|Infant, Moderate Preterm
Interventions: PROCEDURE: Weaning from an incubator at a lower weight (1600 grams)|PROCEDURE: Weaning from an incubator at a higher weight (1800 grams)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DAMP-Mediated Innate Immune Failure and Pneumonia After Trauma - the Harvard-Longwood (HALO) Campus Area Consortium
Status: TERMINATED
Conditions: Respiratory Failure
Interventions: OTHER: Normoxia with Normocarbia|OTHER: Normoxia with Hypercarbia|OTHER: Hyperoxia with Normocarbia|OTHER: Hyperoxia with Hypercarbia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Compare Efficacy, Safety, and Immunogenicity of Proposed Rituximab Biosimilar (DRL_RI) With MabThera® in LTB Follicular Lymphoma
Status: COMPLETED
Conditions: Follicular Lymphoma
Interventions: BIOLOGICAL: DRL_RI (Proposed rituximab biosimilar)|OTHER: MabThera®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FAPI PET for Lung Fibrosis
Status: RECRUITING
Conditions: Interstitial Lung Disease|Idiopathic Interstitial Pneumonias|Drug-Induced Pneumonitis|Hypersensitivity Pneumonitis|Radiation Pneumonitis|Pneumoconiosis|Pulmonary Fibrosis
Interventions: DRUG: 68Ga-FAPi-46|PROCEDURE: Computed Tomography|PROCEDURE: Positron Emission Tomography|PROCEDURE: High Resolution Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Performance and Acceptance of Optive Versus Hylocomod Eyedrops in Patients With Dry Eye Symptoms
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: A sterile solution containing sodium carboxymethylcellulose and glycerin, preserved with PURITE®|DRUG: Sodium hyaluronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of SSRI-Resistant Depression In Adolescents (TORDIA)
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Fluoxetine|DRUG: Venlafaxine|BEHAVIORAL: Cognitive Behavioral Therapy (CBT)|DRUG: Citalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of GN-037 Cream for Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: GN037|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study to Evaluate the Accuracy and Safety of the GlySure Continuous Intravascular Glucose Monitoring System Versus Intermittent Blood Glucose Monitoring
Status: COMPLETED
Conditions: Continuous Glucose Measurement
Interventions: DEVICE: Continuous Glucose Monitoring System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of High-dose Urso in Primary Sclerosing Cholangitis
Status: TERMINATED
Conditions: Primary Sclerosing Cholangitis
Interventions: DRUG: Ursodeoxycholic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects Of Oral Alfacalcidol On Maturation Of Dendritic Cells In Graves' Disease Patients
Status: COMPLETED
Conditions: Graves Disease
Interventions: DRUG: 1α-D3|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can Treatment With Bismuth Reduce Toxicity to Chemotherapy and Radiotherapy?
Status: COMPLETED
Conditions: Hematological Diseases|Hematological Malignancies|Blood Diseases|Malignant Lymphoma|Leukemia|Multiple Myeloma
Interventions: DRUG: Bismuth tablets|DRUG: Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transverses Abdominis Plane Block Versus Local Wound Infiltration in Total Abdominal Hysterectomy
Status: COMPLETED
Conditions: Pain
Interventions: PROCEDURE: Transverses Abdominis Plane Block|PROCEDURE: Local wound infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: IVUS-guided DES Implantation in Coronary Calcification
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Intravascular ultrasound|PROCEDURE: Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Wearable Technology and Smart Phone Applications Based Exercise Training in Patients With Type 2 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Wearable watch training group.|BEHAVIORAL: Mobile application training group.|BEHAVIORAL: Supervised exercise training group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Safety of GlaxoSmithKline (GSK) Vaccines' Quadrivalent Seasonal Influenza Vaccine, Fluarix Tetra When Administered According to the Approved Prescribing Information (PI) in Korea.
Status: COMPLETED
Conditions: Influenza, Human
Interventions: OTHER: Data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: REBOA in Life-threatening Postpartum Hemorrhage (PPH) in Uganda
Status: RECRUITING
Conditions: Post-partum Hemorrhage
Interventions: DEVICE: REBOA, Resuscitative Endovascular Occlusion of the Aorta|OTHER: National guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib and Pembrolizumab Combination Therapy In HPV-associated Recurrent Respiratory Papilloma Patients With Laryngeal, Tracheal, and/or Pulmonary Involvement
Status: NOT_YET_RECRUITING
Conditions: Human Papilloma Virus|Recurrent Respiratory Papillomatosis
Interventions: DRUG: Lenvatinib|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Submerged Versus Non-Submerged Healing of Implants Subjected To Contour Augmentation
Status: COMPLETED
Conditions: Tooth Loss
Interventions: PROCEDURE: Transmucosal Technique|PROCEDURE: Submerged Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Preoperative Dexamethasone for Quality of Recovery in VATS Lung Resection Patients
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Dexamethasone IV|DRUG: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Observational Study of Intra-operative Partial Irradiation of Invasive Ductal Breast Carcinomas With a Good Prognosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Invasive Breast Cancer|Breast-conserving Surgery
Interventions: PROCEDURE: tumorectomy with axillary dissection (sentinel lymph node)|RADIATION: per-operative partial irradiation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of IAM With an I-gel® on Ventilation Parameters in Simulated Pediatric OHCA
Status: COMPLETED
Conditions: Pediatric ALL|Cardiac Arrest|Cardiopulmonary Arrest|Resuscitation|Pediatric Emergency Medicine
Interventions: DEVICE: i-gel ® device|DEVICE: bag-valve-mask ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Fluid Retention Due to Superpotent Topical Corticosteroid
Status: UNKNOWN
Conditions: Bullous Pemphigoid
Interventions: PROCEDURE: Impedance analysis|DRUG: Clobetasol Propionate cream treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: cytarabine|DRUG: etoposide|DRUG: idarubicin|DRUG: mitoxantrone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: ID HBV Vaccination With Imiquimod in OBI
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: Imiquimod + ID HBVv|BIOLOGICAL: Aqueous + ID HBVv|BIOLOGICAL: Imiquimod + IM HBVv
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of TS-143 in Healthy Adult Male Subjects (Multiple-Dose Administration)
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: TS-143|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Role of Vitamin D3 Supplementation With Conventional Synthetic Disease Modifying Antirheumatic Drugs(csDMARD) in Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Augmentation of Cognitive Behavioral Therapy With Transcranial Direct Current Stimulation for Obsessive-Compulsive Disorder (OCD)
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: COMBINATION_PRODUCT: ERP combined with high-definition active tDCS|COMBINATION_PRODUCT: ERP combined with sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Versus Fluoroscopy Guided Superior Hypogastric Plexus Block in Cancer Bladder Patients
Status: UNKNOWN
Conditions: Pain, Chronic
Interventions: PROCEDURE: Fluoroscopy-guided superior hypogastric plexus block transdiscal approach|PROCEDURE: ultrasound-guided superior hypogastric plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Testing the Addition of a New Immunotherapy Drug, Atezolizumab (MPDL3280A), to the Usual Chemoradiation (CRT) Therapy Treatment for Limited Stage Small Cell Lung Cancer (LS-SCLC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Limited Stage Lung Small Cell Carcinoma|Stage I Lung Cancer AJCC v8|Stage II Lung Cancer AJCC v8|Stage III Lung Cancer AJCC v8
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|DRUG: Atezolizumab|PROCEDURE: Biospecimen Collection|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Etoposide|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magic Shave Powder Gold's Affects on the Occurrence of Pseudofolliculitis Barbae
Status: WITHDRAWN
Conditions: Pseudofolliculitis Barbae
Interventions: DRUG: Magic Shave Powder Gold|DEVICE: Traditional Shaving Methods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Patient Specific Intraoral Inverted-L Osteotomy Modified With Inferior Alveolar Nerve Relocation in Corrective Mandibular Surgery
Status: COMPLETED
Conditions: Class III Malocclusion
Interventions: PROCEDURE: patient specific inverted L mandibular osteotomy modified with inferior alveolar nerve relocation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bag Valve Mask vs Non-rebreather at Flush Rate
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: OTHER: Flush rate oxygen using a standard flowmeter (Precision Medical, 8MFA). See description for details. This is specific.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Myelodysplastic Syndromes (MDS) Event Free Survival With Iron Chelation Therapy Study
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Deferasirox|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MK4827 in Participants With Advanced Solid Tumors or Hematologic Malignancies (MK-4827-001 AM8)
Status: COMPLETED
Conditions: Solid Tumors|Chronic Lymphocytic Leukemia|T-cell-prolymphocytic Leukemia
Interventions: DRUG: MK-4827
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy Plus Xevinapant in Older Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma
Status: SUSPENDED
Conditions: Locally Advanced Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Xevinapant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing the Tolerable Upper Intake Level and Safety of Sugars From Fiber
Status: COMPLETED
Conditions: Gastrointestinal Tolerance
Interventions: OTHER: Sugars from Fiber|OTHER: Resistant Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: L-DEP as an Initial Treatment for EBV-HLH
Status: UNKNOWN
Conditions: Hemophagocytic Lymphohistiocytosis
Interventions: DRUG: Pegaspargase|DRUG: doxorubicin hydrochloride liposome injection|DRUG: etoposide|DRUG: methylprednisolone|DRUG: Etoposide|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Prednisone and Azithromycin in the Treatment of Patients With Cat Scratch Disease
Status: UNKNOWN
Conditions: Cat-scratch Disease|Bartonella Infections
Interventions: DRUG: prednison and azithromycin|DRUG: prednison, azithromycin|DRUG: prednison, Azenil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study: Darbepoetin Alfa for the Treatment of Anemia in Patients With Chronic Kidney Disease
Status: COMPLETED
Conditions: Anemia|Kidney Disease
Interventions: DRUG: Darbepoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Paracetamol With Caffeine to Treat Episodic Tension Type Headache
Status: TERMINATED
Conditions: Headache, Tension-Type
Interventions: DRUG: Placebo|DRUG: Experimental paracetamol + caffeine formulation|DRUG: ibuprofen marketed formulation|DRUG: Paracetamol marketed formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: tDCS in Post-COVID Syndrome: Comparison of Two Targets
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19|Post-COVID-19 Syndrome|Post COVID-19 Condition
Interventions: DEVICE: transcranial current direct stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Are Paraspinous Intramuscular Injections of Botulinum Toxin A (BoNT-A) Efficient in the Treatment of Chronic Low-back Pain (LBP)?
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: DRUG: Botox|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) of TAK-228 as Single Agent in Adult East Asian Participants With Advanced Nonhematological Malignancies
Status: TERMINATED
Conditions: Advanced Nonhematological Neoplasms
Interventions: DRUG: TAK-228
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of America
Status: COMPLETED
Conditions: Malaria|Plasmodium Falciparum Malaria
Interventions: BIOLOGICAL: Falciparum Malaria Protein 11 with AS02A adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Clinical Study of Improving the Thirst and Hypotension of Hemodialysis Patients
Status: UNKNOWN
Conditions: Intradialytic Hypotension
Interventions: DRUG: Ear pills|DRUG: Shengmai capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation in Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prepectoral vs Partial Subpectoral Two-Stage Implant-Based Breast Reconstruction
Status: WITHDRAWN
Conditions: Breast Reconstruction Following Mastectomy
Interventions: PROCEDURE: Prepectoral approach|PROCEDURE: Partial Subpectoral approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment and Comparison of Metabolic Changes in Non-psychotic Adults Taking Iloperidone or Olanzapine or Placebo
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: olanzapine|DRUG: iloperidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Prophylactic Biliary Stent in Reducing the Recurrence of Choledocholithiasis
Status: NOT_YET_RECRUITING
Conditions: Choledocholithiasis
Interventions: PROCEDURE: Group A - Stent exchange if cholecystectomy dated beyond 3 months|DIAGNOSTIC_TEST: Group B - Diagnostic EUS/MRCP/USG abdomen and LFT at 3 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Remineralizing and Antibacterial Effect of Natural Versus Synthetic Materials on Deep Carious Dentin
Status: COMPLETED
Conditions: Dentin Caries
Interventions: OTHER: hesperidine|OTHER: propolis|OTHER: silver diamine fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Safety and Effectiveness of Infliximab (Remicade) in Patients With Pancreatic Cancer Related Cachexia
Status: COMPLETED
Conditions: Cachexia|Pancreatic Neoplasms
Interventions: DRUG: Infliximab; Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Characterization of Medical Student Burnout Using Remote Physiologic Monitoring
Status: UNKNOWN
Conditions: Wellness|Burnout|Remote Monitoring
Interventions: DEVICE: WHOOP strap 4.0 (full data access)|DEVICE: WHOOP strap 4.0 (partial data access)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC