pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Impact of Maternal Supplementation With Dual Megadose of Vitamin A
Status: COMPLETED
Conditions: Hypovitaminosis|Vitamin A Deficiency
Interventions: DIETARY_SUPPLEMENT: vitamin A|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Alignment Comparison Between TruMatch™ Personalized Solutions and Conventional Total Knee Replacement Instrumentation
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: TruMatch™ Personalized Solutions|DEVICE: Total Knee Arthroplasty with Conventional Instrumentation.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FMT for MDRO Colonization in Solid Organ Transplant
Status: WITHDRAWN
Conditions: Infection Due to Resistant Organism
Interventions: BIOLOGICAL: OpenBiome Fecal Microbiota Transplantation retention enema
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Prazosin Versus Placebo Associated With Peg-Interferon Alpha 2b and Ribavirin in Chronic Hepatitis C With Genotype 1 or 4 and Severe Fibrosis
Status: UNKNOWN
Conditions: Hepatitis C, Chronic|Fibrosis
Interventions: DRUG: Peg-interferon alpha 2b (drug)|DRUG: Ribavirin (drug)|DRUG: Prazosin (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Telehealth Oncofertility Care Intervention in Adolescent and Young Adult Cancer Patients
Status: RECRUITING
Conditions: Cancer|Fertility Preservation
Interventions: BEHAVIORAL: Multi-component oncofertility care intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Drug-Drug Interaction Study to Evaluate Drug Transporter Interactions
Status: COMPLETED
Conditions: Hereditary Angioedema
Interventions: DRUG: BCX7353|DRUG: Digoxin|DRUG: BCX7353 + digoxin|DRUG: Rosuvastatin|DRUG: rosuvastatin + BCX7353|DRUG: Cyclosporine + BCX7353
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of BI201335 in Treatment-naive and Prior Relapser Patients With Chronic Hepatitis C Infection
Status: WITHDRAWN
Conditions: Hepatitis C, Chronic
Interventions: DRUG: PegIFN/RBV|DRUG: BI 201335|DRUG: BI 201335|DRUG: PegIFN/RBV|DRUG: BI 201335
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pain Trajectories After Surgery and Their Potential Relationship With Chronicity at 3 Months
Status: UNKNOWN
Conditions: Surgical Procedures, Operative|Pain|Chronic Pain
Interventions: OTHER: In hospital pain evaluation|OTHER: In hospital questionnaires|OTHER: Telephone contact at 3 months
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sustained Acoustic Medicine for Symptomatic Treatment of Knee Pain Related to Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Osteo Arthritis Knee|Arthritis
Interventions: DEVICE: Sustained Acoustic Device with 2.5% Diclofenac Patch|DEVICE: Sustained Acoustic Device with 0% Diclofenac Patch|DRUG: 2.5% Diclofenac Patches|OTHER: SAM Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of APG-1252 Plus Paclitaxel in Patients With Relapsed/Refractory Small Cell Lung Cancer
Status: TERMINATED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: APG-1252|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunization of Disease-Free Melanoma Patients With Different HLA-A2 Peptides
Status: TERMINATED
Conditions: Melanoma
Interventions: BIOLOGICAL: Immunological peptides and immunological adjuvants|BIOLOGICAL: HLA-A2 peptides|BIOLOGICAL: Montanide ISA51|BIOLOGICAL: IMP321
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does ESWT With BoNTA Treatment Improve Outcomes When Compared to Standard Management for Upper Limb Spasticity Patient.
Status: RECRUITING
Conditions: Spasticity, Muscle
Interventions: DEVICE: ESWT (extra-corporeal shock wave therapy)|DEVICE: Sham : The ESWT device (Storz Medical Duolith SD1),
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chloroquine and Post Malaria Anaemia Study
Status: COMPLETED
Conditions: Malaria Anaemia
Interventions: DRUG: Chloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Innovative Model of Patient-Centered ConTraception
Status: COMPLETED
Conditions: Contraception|Unintended Pregnancy
Interventions: BEHAVIORAL: CHOICE Project Structured Contraceptive Counseling|BEHAVIORAL: Contraceptive Education Session|DEVICE: Cost Support for IUDs and implants
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: RNASARC - Molecular Screening Program of Soft Tissue Sarcomas With Complex Genomic Profile to Detect NTRK1/2/3, ROS1 or ALK Gene Fusions.
Status: ACTIVE_NOT_RECRUITING
Conditions: Soft Tissue Sarcoma|Advanced Cancer|Metastatic Cancer
Interventions: GENETIC: Blood and tumor samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safety of a Quadrivalent Influenza Vaccine (VaxigripTetra™) in Subjects Aged 6 Months and Older in Vietnam
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Quadrivalent Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mobile Evidence-Based Smoking Cessation for Veterans Living With HIV (MESH)
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|Smoking
Interventions: DRUG: Bupropion|DRUG: Varenicline|BEHAVIORAL: Cognitive Behavioral Therapy|DRUG: Nicotine Replacement Therapy|BEHAVIORAL: Relapse Prevention Text Messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Learning to Resist the Urge: Inhibition Training in Abstinent Patients With Alcohol Use Disorders
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: BEHAVIORAL: Alc-IT (50/50) (morning)|BEHAVIORAL: Alc-IT (75/25) (morning)|BEHAVIORAL: Control-training (morning)|BEHAVIORAL: Alc-IT (50/50) (afternoon)|BEHAVIORAL: Alc-IT (75/25) (afternoon)|BEHAVIORAL: Control-training (afternoon)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Greater Occipital Nerve Pulsed Radiofrequency for the Treatment of Combined Migraine and Cervicogenic Headache (New Approach)
Status: COMPLETED
Conditions: Greater Occipital Nerve|Pulsed Radiofrequency
Interventions: PROCEDURE: proximal ultrasound-guided GON radiofrequency ablation|PROCEDURE: distal ultrasound-guided GON radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Web-based Sexual Violence Risk Reduction Program for Female College Students
Status: COMPLETED
Conditions: Sexual Violence
Interventions: BEHAVIORAL: RealConsent|BEHAVIORAL: Stress and Mood Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Ferric Carboxymaltose (FCM) Versus Standard of Care in Treating Iron Deficiency Anemia
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Ferric Carboxymaltose (FCM)|DRUG: Standard Medical Care (SMC) for the treatment of IDA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunosafety Study of Recombinant Human Insulins in Type 1 Diabetics
Status: TERMINATED
Conditions: Type I Diabetes
Interventions: BIOLOGICAL: Wosulin (N or 70/30 with R)|BIOLOGICAL: Novolin® (N or 70/30 with R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of mDOT for Immunosuppressant Adherence in Adolescent Kidney Transplant Recipients
Status: COMPLETED
Conditions: Medication Adherence|Kidney Transplant
Interventions: OTHER: mHealth Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of SHR-A1811 in First-line Treatment of Patients With Advanced or Metastatic Non-small Cell Lung Cancer With HER2 Mutations
Status: NOT_YET_RECRUITING
Conditions: Non-Small Cell Lung Cancer With HER2- Mutations
Interventions: DRUG: SHR-A1811|DRUG: Camrelizumab、Pemetrexed/ Paclitaxel、Carboplatin/ Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: mFOLFOX6+Bevacizumab+PD-1 Monoclonal Antibody in Local Advanced MSS CRC
Status: RECRUITING
Conditions: Colorectal Cancer|Immunotherapy
Interventions: DRUG: mFOLFOX6+Bevacizumab+PD-1 monoclonal antibody treatment combinations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Therapeutic Effects of Sapropterin Dihydrochloride on Neuropsychiatric Symptoms in Phenylketonuria (PKU) Patients
Status: COMPLETED
Conditions: Phenylketonuria
Interventions: DRUG: Sapropterin dihydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IntelliStent for Pulmonary Flow Adjustment in Congenital Heart Disease and Dilated Cardiomyopathy
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Arterial Hypertension|Dilated Cardiomyopathy|Congenital Heart Disease
Interventions: DEVICE: IntelliStent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GRACE: Evaluating Compression Stockings in Patients That Require Extended Duration Pharmacological Thromboprophylaxis
Status: RECRUITING
Conditions: Venous Thromboembolism|Surgery
Interventions: OTHER: Graduated compression stockings|OTHER: No Graduated compression stockings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Eltrombopag Plus rhTPO Versus Eltrombopag for ITP During the COVID-19 Pandemic (ELABORATE-19)
Status: UNKNOWN
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Eltrombopag|DRUG: rhTPO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate and Long-term Induction of Incretin Release by Artificial Sweeteners 2
Status: COMPLETED
Conditions: Diabetes|Pre-diabetes
Interventions: DIETARY_SUPPLEMENT: custom-made soft drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Small Intestinal Bacterial Overgrowth Obese
Status: COMPLETED
Conditions: Gastric Bypass|Blind Loop Syndrome|Bacterial Overgrowth Syndrome|Chromatography, Gas
Interventions: PROCEDURE: gas chromatography|PROCEDURE: Stool analysis for detection of malabsorption
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Role of 3 Tesla Diffusion Weighted Magnetic Resonance Imaging (DW-MRI) for Diagnosis Bladder Cancer Grade and Stage
Status: UNKNOWN
Conditions: Bladder Cancer|Diagnoses Disease|Magnetic Resonance Imaging|Apparent Diffusion Coefficient
Interventions: DIAGNOSTIC_TEST: Magnetic resonance imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Diagnostic Imaging Utilization Reports
Status: COMPLETED
Conditions: Diagnostic Imaging Utilization
Interventions: OTHER: Usual QCNL DI utilization report|OTHER: New DI utilization report|OTHER: Detailing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Initial Graft Tension and ACL Surgery
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Rupture
Interventions: PROCEDURE: Initial graft tension during ACL reconstruction surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the CD73 Inhibitor LY3475070 Alone or in Combination With Pembrolizumab in Participants With Advanced Cancer
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: LY3475070|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nintedanib (Vargatef®) Plus Docetaxel in Second Line of Treatment in Patients With Lung Cancer
Status: COMPLETED
Conditions: Lung Neoplasms
Interventions: DRUG: vargatef®|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating DVS-233 SR and Venlafaxine ER in Adult Outpatients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: DVS-233 SR|DRUG: Venlafaxine ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Probiotics as Adjunctive Migraine Prophylaxis
Status: RECRUITING
Conditions: Migraine|Episodic Migraine
Interventions: DIETARY_SUPPLEMENT: (Microbial cell preparation) probiotics|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Imaging Modality by Positron Emission Tomography Using 18F-X : Study of Microglial Activation in Amyotrophic Lateral Sclerosis
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis|Bulbar Disease|Spinal Disease
Interventions: RADIATION: 18F-X PET SCAN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of Reaching Task Following Selective Trunk Stability Exercise
Status: RECRUITING
Conditions: Cerebral Stroke|Hemiplegia, Spastic
Interventions: BEHAVIORAL: Abdominal drawing-in maneuver exercise|BEHAVIORAL: sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Dental Implants in The Upper Anterior Region
Status: NOT_YET_RECRUITING
Conditions: Teeth Loss|Alveolar Bone Resorption
Interventions: OTHER: Group A : ice cream cone technique|OTHER: Group B : the vestibular socket therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Novel "Pediatric-Inspired" Regimen With Reduced Myelosuppressive Drugs for Adults (Aged 18-60) With Newly Diagnosed Ph Negative Acute Lymphoblastic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia
Interventions: DRUG: Daunorubicin|DRUG: Vincristine|DRUG: Prednisone|DRUG: PEG-Asparaginase|DRUG: Methotrexate|DRUG: 6-MP (6-Mercaptopurine)|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Leucovorin|DRUG: Dexamethasone|OTHER: Blood draw|DEVICE: CT/PET scans
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expanded Activated Lymphocytes (EAL) as Adjuvant Therapy in Patients With HCC at High Risk of Recurrence After Radical Resection
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma (HCC)
Interventions: BIOLOGICAL: Expanded Activated Lymphocytes (EAL)|PROCEDURE: transarterial chemoembolization (TACE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bridge or Continue Coumadin for Device Surgery Randomized Controlled Trial
Status: TERMINATED
Conditions: Hematoma
Interventions: DRUG: low molecular weight heparin or unfractionated heparin|DRUG: Warfarin or coumadin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Monitoring of Allergic and Asthmatic Symptoms in Patients Taking Dietary Supplements Joalis Bambi Bronchi and Joalis Bambi Analerg
Status: UNKNOWN
Conditions: Children
Interventions: DIETARY_SUPPLEMENT: Joalis Bambi Analerg|DIETARY_SUPPLEMENT: Joalis Bambi Bronchi|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Phase I, Study to Evaluate the Safety and Tolerability of Intravenous EZN-2208 in Patients With Advanced Solid Tumors or Lymphoma (EZN-2208-01)
Status: COMPLETED
Conditions: Advanced Solid Tumors|Lymphoma
Interventions: DRUG: EZN-2208
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Study of the Effects of BMS-919373 on the Electrical Activity of the Heart Using Pacemakers
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: DRUG: BMS-919373|DRUG: Sotalol|DRUG: Placebo for BMS-919373
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Investigate How Common Pancreatic Exocrine Insufficiency (PEI) is in Patients With Type 2 Diabetes and Also to Investigate the Uptake of a Single Dose of EPANOVA® or OMACOR® in Patients With Different Degrees of PEI
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Exocrine Pancreatic Insufficiency
Interventions: DRUG: Epanova® (omega-3 carboxylic acids)|DRUG: Omacor® (omega-3-acid ethyl esters)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Bilateral Asymmetrical Limbs Proprioceptive Neuromuscular Facilitation on Multifidus Muscle in CLBP.
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Group A (PNF rhythmic initiation group )|OTHER: Group B (Swiss ball exercises)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutrition-support-team Based Intervention in Patients With Advanced Gastrointestinal Cancer
Status: UNKNOWN
Conditions: Malnutrition|Gastrointestinal Cancer|Nutrition Aspect of Cancer
Interventions: OTHER: NST group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Oral Pre-loads on Subsequent Energy Intake
Status: COMPLETED
Conditions: Energy Intake|Gastrointestinal Hormones|Glycemic Control|Appetite|Satiation
Interventions: DIETARY_SUPPLEMENT: Erythritol|DIETARY_SUPPLEMENT: Sucrose|DIETARY_SUPPLEMENT: Sucralose|DIETARY_SUPPLEMENT: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimal Bupivacaine Dose for Initiation of Labor Epidural Techniques
Status: COMPLETED
Conditions: Labor Pain|Analgesia
Interventions: DRUG: Bupivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Bioequivalence of Dapagliflozin/Metformin XR Fixed-dose Combination Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Bioequivalence|Fixed Dose Combination Tablets|Healthy Male and Female Subjects
Interventions: DRUG: dapagliflozin/metformin XR 5/500 mg test drug (Mount Vernon)|DRUG: dapagliflozin/metformin XR 5/500 mg reference drug (Humacao)|DRUG: dapagliflozin/metformin XR 10/1000 mg test drug (Mount Vernon)|DRUG: dapagliflozin/metformin XR 10/1000 mg reference drug (Humacao)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Inspiratory Flow Parameters of Easyhaler and Diskus Inhalers (SALIF)
Status: COMPLETED
Conditions: Asthma|Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Easyhaler type A|DEVICE: Easyhaler type B|DEVICE: Diskus inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: THE EFFECT OF COGNITIVE AWARENESS SUPPORT ON THE PSYCHOSOCIAL STATUS OF WOMEN TREATED FOR INFERTILITY
Status: COMPLETED
Conditions: Infertility|Infertility, Female
Interventions: BEHAVIORAL: Mindfulness based phone app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nab-paclitaxel Versus Topotecan As Second-Line Treatment for Patients With Extensive Stage Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Extensive Stage Small Cell Lung Cancer
Interventions: DRUG: nab-paclitaxel|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Bioinductive Implant for Tennis Elbow (Lateral Epicondylitis)
Status: RECRUITING
Conditions: Tennis Elbow|Lateral Epicondylitis
Interventions: BIOLOGICAL: Smith & Nephew Bioinductive Implant|PROCEDURE: Lateral Epicondylectomy|RADIATION: Ultrasound Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Shi's Traumatology Osteopathic Manipulative Treatment for Cervicogenic Dizziness
Status: RECRUITING
Conditions: Cervicogenic Dizziness
Interventions: OTHER: Shi's traumatology osteopathic manipulation|DRUG: Merislon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coronary Arteriogenetic Heparinized Exercise
Status: COMPLETED
Conditions: Refractory Angina|Chronic Stable Angina
Interventions: OTHER: Physical rehabilitation|DRUG: Heparin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Exercise on Tissue Beta-alanine Uptake and Carnosine Synthesis Rates
Status: UNKNOWN
Conditions: Exercise Training|Carnosine|Dietary Supplements
Interventions: DIETARY_SUPPLEMENT: Beta-alanine supplementation|OTHER: High intensity interval exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Relationship Between Serum Selenium Level and Glycemic Control in Pregnant Patients*
Status: NOT_YET_RECRUITING
Conditions: Gestational Diabetes|Pregnancy Related
Interventions: DIETARY_SUPPLEMENT: selenium+ diet|DIETARY_SUPPLEMENT: only diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of Intravenous Alpha-1 Antitrypsin in Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Alpha-1 Antitrypsin 40mg (AAT, Glassia®)|DRUG: Alpha-1 Antitrypsin 60mg (AAT, Glassia®)|DRUG: Alpha-1 Antitrypsin 80mg (AAT, Glassia®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2/3 Study of TLC590 for Postsurgical Pain Management
Status: NOT_YET_RECRUITING
Conditions: Postsurgical Pain Management
Interventions: DRUG: TLC590|DRUG: Bupivacain|DRUG: Ropivacaine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Whether BI 655130 (Spesolimab) Prevents Flare-ups in Patients With Generalized Pustular Psoriasis
Status: COMPLETED
Conditions: Generalized Pustular Psoriasis
Interventions: DRUG: Spesolimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nitazoxanide in Prevention of Secondary Spontaneous Peritonitis
Status: UNKNOWN
Conditions: Spontaneous Bacterial Peritonitis
Interventions: DRUG: Nitazoxanide|DRUG: Norfloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Ultrasound-guided Piriformis Muscle Corticosteroid Injection Versus Extracorporeal Shock Wave Therapy for Piriformis Syndrome: a Randomized Control Trial
Status: COMPLETED
Conditions: Piriformis Syndrome|Corticosteroid Injection|Extracorporeal Shockwave Therapy|Therapeutic Exercise
Interventions: PROCEDURE: Extracorporeal shockwave therapy (ESWT)|PROCEDURE: Ultrasound-guided piriformis steroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Influence of Aromatherapy and Music Therapy on Stress During the Management of Cerebral Arteriography
Status: NOT_YET_RECRUITING
Conditions: Patients Scheduled for Cerebral Arteriography for Diagnostic or Therapeutic Purposes
Interventions: OTHER: music therapy|OTHER: aromatherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long Term Monitoring for Risk of Sudden Death
Status: COMPLETED
Conditions: Inherited Cardiac Arrhythmias|Long QT Syndrome|Arrhythmogenic Right Ventricular Cardiomyopathy|Brugada Syndrome|Catecholaminergic Polymorphic Ventricular Tachycardia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diesel Exhaust and Vascular Function
Status: UNKNOWN
Conditions: Cardiovascular Effects
Interventions: OTHER: Diesel Exhaust|OTHER: Filtered Air|DRUG: Terazosin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Acceptability and Feasibility of a Bedtime Routine for Neonates
Status: RECRUITING
Conditions: Newborn
Interventions: OTHER: Baby Wash/Shampoo|OTHER: Daily Activities|OTHER: Body Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dinaciclib in Treating Patients With Stage IV Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Acral Lentiginous Melanoma|Cutaneous Nodular Melanoma|Lentigo Maligna Melanoma|Low-CSD Melanoma|Mucosal Melanoma|Recurrent Melanoma|Stage IV Cutaneous Melanoma AJCC v6 and v7
Interventions: DRUG: Dinaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Use of Teriparatide and Raloxifene in Postmenopausal Women With Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: teriparatide|DRUG: raloxifene|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Immune Response to Five Different Combinations of HIV Vaccines in Healthy, HIV-Uninfected Adults
Status: WITHDRAWN
Conditions: HIV Infections
Interventions: BIOLOGICAL: DNA-HIV-PT123|BIOLOGICAL: NYVAC-HIV-PT1|BIOLOGICAL: NYVAC-HIV-PT4|BIOLOGICAL: AIDSVAX B/E®|BIOLOGICAL: Placebo vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dabrafenib Alone and in Combination With Trametinib Before Surgery in Treating Patients With Locally or Regionally Advanced Melanoma That Can Be Removed By Surgery
Status: TERMINATED
Conditions: Recurrent Melanoma|Stage IIB Melanoma (Locally Advanced)|Stage IIC Melanoma (Locally Advanced)|Stage IIIA Melanoma|Stage IIIB Melanoma|Stage IIIC Melanoma|Stage IV Melanoma (Limited, Resectable)
Interventions: DRUG: dabrafenib|DRUG: trametinib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Prospective, Open, Multicenter Single-arm Clinical Studie of Docetaxel, Carboplatin Combined With Inetetamab and Pyrotinib in the Treatment of Local-advanced HER2-positive Breast Cancer
Status: RECRUITING
Conditions: Breast Neoplasm Female
Interventions: DRUG: Docetaxel|DRUG: Carboplatin|DRUG: Inetetamab|DRUG: Pyrotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Infant Placement on Iron Stores in Infancy: A Pilot Study
Status: UNKNOWN
Conditions: Iron Deficiency|Anemia
Interventions: PROCEDURE: perineum maintained|PROCEDURE: abdominal placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: FCN-159 in Adult Patients With Symptomatic, Inoperable Neurofibromatosis Type 1-Related Plexiform Neurofibromas
Status: RECRUITING
Conditions: Neurofibromatosis 1|Plexiform Neurofibroma|NF1
Interventions: DRUG: Test group (Group A): FCN-159 8 mg, orally, once daily;|DRUG: Control group (Group B): Placebo, orally, once daily;
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zoledronic Acid to Maintain Bone Mass After Denosumab Discontinuation
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Denosumab|DRUG: Zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FE-SaLiR: Function Improvement Exercise
Status: UNKNOWN
Conditions: Disability Physical|Cognitive Impairment
Interventions: BEHAVIORAL: Modified FE-SaLiR|BEHAVIORAL: Unmodified Chinese Medicine Exercise|BEHAVIORAL: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trial to Define the Safety and Tolerability of SGN-40, Rituximab, and Gemcitabine in Patients With DLBCL
Status: COMPLETED
Conditions: Lymphoma, Large B-Cell, Diffuse|Lymphoma, Non-Hodgkin
Interventions: DRUG: SGN-40|DRUG: rituximab|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Conversion Study to Assess Safety and Efficacy of a MR4 Based Immunosuppressive Regimen in Stable Kidney Recipients
Status: COMPLETED
Conditions: Transplantation
Interventions: DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization of Chest Tube Drainage Management
Status: COMPLETED
Conditions: Lung Diseases|Age >18 Years-old|Patient Who Received Thoracoscope Surgery
Interventions: DEVICE: Digital chest drainage system|DEVICE: Not use Digital chest drainage system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture Treatment for Active Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DEVICE: Acupuncture and moxibustion|DEVICE: Sham acupuncture and moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Intrathecal Morphine and Dexmedetomidine Analgesia
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Dexmedetomidine (Precedex)|DRUG: Bupivacaine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Modulation of Cognition and Brain Activity
Status: RECRUITING
Conditions: Nutrition, Healthy|Cognitive Change|Brain Activity
Interventions: OTHER: Dietary intervention: Standardized breakfast with varying amounts of macronutrients (in particular carbohydrate/protein ratios)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fulvestrant Combined Anastrozole Versus Anastrozole in Luminal A-like Postmenopausal ABC
Status: WITHDRAWN
Conditions: Carcinoma Breast Stage IV
Interventions: DRUG: Fulvestrant|DRUG: Anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Corticospinal Excitability Aspects of Itch and Pain
Status: NOT_YET_RECRUITING
Conditions: Itch|Pain
Interventions: OTHER: Hypertonic Saline|OTHER: Histamine|OTHER: Cowhage|DEVICE: Transcranial magnetic stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: TRK-100STP Clinical Study - Chronic Renal Failure (Primary Glomerular Disease/Nephrosclerosis)
Status: COMPLETED
Conditions: Chronic Renal Failure|Glomerular Disease|Nephrosclerosis
Interventions: DRUG: TRK-100STP high dose|DRUG: TRK-100STP low dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Pessary Versus Standard Management in Women With Increased Chance of Premature Birth
Status: COMPLETED
Conditions: Preterm Birth
Interventions: DEVICE: Vaginal pessary (CE0482, MED/CERT ISO 9003 / EN 46003)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Testing for the Presence of Authorship Bias in Peer Review
Status: COMPLETED
Conditions: Peer Review
Interventions: OTHER: Blinded manuscript|OTHER: Unblinded manuscript
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of NGM707 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Mesothelioma|Glioblastoma|Renal Cell Carcinoma|Non Small Cell Lung Cancer|Melanoma|Pancreatic Ductal Adenocarcinoma|Gastric Cancer|Squamous Cell Carcinoma of Head and Neck|Cholangiocarcinoma|Breast Cancer|Ovarian Cancer|Cervical Cancer|Endocervical Cancer|Colorectal Cancer|Esophageal Cancer
Interventions: DRUG: NGM707|DRUG: NGM707 plus pembrolizumab (KEYTRUDA®)|DRUG: NGM707 plus pembrolizumab (KEYTRUDA®)|DRUG: NGM707 plus pembrolizumab (KEYTRUDA®)|DRUG: NGM707 plus pembrolizumab (KEYTRUDA®)|DRUG: NGM707|DRUG: NGM707|DRUG: NGM707
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide or Observation in Treating Patients With Asymptomatic High-Risk Smoldering Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Light Chain Deposition Disease|Smoldering Multiple Myeloma
Interventions: OTHER: Clinical Observation|DRUG: Lenalidomide|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Activated CIK Armed With Bispecific Antibody for Advanced Liver Cancer
Status: UNKNOWN
Conditions: Advanced Liver Cancer
Interventions: BIOLOGICAL: Activated CIK|BIOLOGICAL: CIK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The De-novo Use of Eculizumab in Presensitized Patients Receiving Cardiac Transplantation
Status: COMPLETED
Conditions: Antibody-mediated Rejection|Hyperacute Rejection of Cardiac Transplant|Left Ventricular Dysfunction|Cardiac Allograft Vasculopathy|Heart Graft Dysfunction
Interventions: DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Neurophysiological Monitoring Detection of Cerebral Vasospasm in Aneurysmal Subarachnoid Hemorrhage Subjects
Status: TERMINATED
Conditions: Cerebral Vasospasm|SAH|Aneurysm
Interventions: OTHER: Neuro Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: P53 Gene Combined With Radio- and Chemo-therapy in Treatment of Unresectable Locally Advanced Head and Neck Cancer
Status: UNKNOWN
Conditions: Advanced Head and Neck Cancer
Interventions: DRUG: rAd-p53|RADIATION: radiation|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of 17ß-estradiol on Inflammatory-immune Responses in Post-menopausal Women According to Administration Route
Status: COMPLETED
Conditions: Postmenopausal
Interventions: DRUG: oestradiol|DRUG: oestradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Anesthetic Choice (Sevoflurane Versus Desflurane) on Airway Reflex Recovery in the Context of Antagonized Neuromuscular Block
Status: COMPLETED
Conditions: Airway Reflexes, Protective|Recovery After Neuromuscular Block|Anesthetic Recovery
Interventions: DRUG: Sevoflurane|DRUG: Desflurane|DRUG: Rocuronium|DRUG: Neostigmine|DRUG: Glycopyrrolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Blunts the Hypotensive Effect of Spinal Anesthesia in Geriatric Patients Undergoing Lower Limb Orthopedic Surgeries
Status: COMPLETED
Conditions: Hypotension
Interventions: DRUG: Dexamethasone phosphate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Coagulation Profiles Between Zoely and Minidoz: RCT
Status: TERMINATED
Conditions: Contraception|Hypercoagulability
Interventions: DRUG: 1.5 mg estradiol and 2.5 mg nomegestrol acetate|DRUG: 15 µg ethinylestradiol and 60 µg gestodene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Screening for Neurodevelopmental Disorders in Siblings of Children With Autism Diagnosed in Tertiary Centers
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder|Siblings|Neurodevelopmental Disorders
Interventions: DIAGNOSTIC_TEST: Step 1 - Screening ; Step 2 - Clinical interview
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: AZD5672 Absolute Bioavailability Study
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AZD5672|DRUG: AZD5672|DRUG: AZD5672
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Pain Management After Surgery When Using Nerve Blocks in the Pediatric Population
Status: NOT_YET_RECRUITING
Conditions: Anterior Cruciate Ligament (ACL) Tear|Sports Injuries in Children|Analgesia|Pain, Postoperative
Interventions: DRUG: Ropivacaine 0.2% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The MOTION Study - Treatment of LSS With the MILD Procedure
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Stenosis, Lumbar Region, With Neurogenic Claudication
Interventions: DEVICE: MILD Procedure|OTHER: Conventional Medical Management (CMM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Zimberelimab|DRUG: Domvanalimab|DRUG: Pembrolizumab|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Paclitaxel|DRUG: Nab-paclitaxel|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Bronchodilator Effects of Ipratropium/Levosalbutamol 20/50 mcg Fixed Dose Combination vs Salbutamol 100 mcg Inhaler Plus Ipratropium 20 mcg Inhalation Aerosol Free Combination in Patients With Stable COPD
Status: WITHDRAWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Ipratropium/Levosalbutamol 20/50 mcg Fixed Dose Combination (2 inhalations) via pMDI|DRUG: Salbutamol 100 mcg Inhaler (2 inhalations) + Ipratropium 20 mcg Inhalation Aerosol (2 inhalations) Free Combination via MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive BCI and Application Verification for Depressed People
Status: RECRUITING
Conditions: Depression|Major Depressive Disorder|Bipolar Depression
Interventions: DRUG: SSRI|DEVICE: rTMS|BEHAVIORAL: Neuro-Feedback|BEHAVIORAL: Game Regulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nerve Transfer for Finger Sensory Reconstruction With Dorsal Branch of the Digital Nerve
Status: COMPLETED
Conditions: Sensory Restoration of the Reconstructed Finger Pulps|Cold Intolerance of the Reconstructed Finger|Pain of the Reconstructed Finger
Interventions: PROCEDURE: Nerve transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Famitinib Plus Anti-PD1 Therapy for Advanced Urinary System Tumor, Advanced Gynecological Tumors
Status: UNKNOWN
Conditions: Renal Cell Carcinoma|Urothelial Carcinoma|Cervical Cancer|Ovarian Cancer Recurrent|Endometrial Cancer
Interventions: BIOLOGICAL: SHR-1210|DRUG: Famitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Services to Enhance Social Functioning in Adults With Autism Spectrum Disorders
Status: COMPLETED
Conditions: Autism|Autism Spectrum Disorder|Autistic Disorder|Asperger Syndrome|Pervasive Developmental Disorder
Interventions: BEHAVIORAL: Training to Understand and Navigate Emotions and Interactions (TUNE In)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study for the Efficacy Evaluation of a Food Supplement
Status: COMPLETED
Conditions: Spot Pigmented|Wrinkle
Interventions: OTHER: Mentha Suaveolens extract incorporated into a food supplement|OTHER: Placebo product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Joint Patient and Caregiver Intervention for Older African Americans With Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Joint Home-DM-BAT Intervention|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Conjoint Analysis of Patient Preferences in Joint Interventions
Status: SUSPENDED
Conditions: Arthritis|Femoroacetabular Impingement|Osteochondritis Dissecans|Hip Fractures|Ankle Fractures|Tibial Fractures
Interventions: OTHER: Decision tool|OTHER: Standard treatment information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Pain Education on Multidisciplinary Healthcare Students' Understanding of Chronic Pain
Status: COMPLETED
Conditions: Knowledge, Attitudes, Practice
Interventions: OTHER: Pain neuroscience education|OTHER: Red flag education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH