pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Double-Blind Pharmacokinetic Interaction Study Evaluating the Effect of a Single IV Infusion of GGF2 or Placebo on Midazolam Pharmacokinetics in Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: OTHER: Placebo|DRUG: GGF2|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Liraglutide on Hippocampal Structure and Function in Aging Adults With Prediabetes
Status: COMPLETED
Conditions: Insulin Resistance|Dementia
Interventions: DRUG: Liraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Microbiota in Urine and Urothelium Can be a Factor for Induction of Urinary Bladder Cancer. The Study Will Examine Urine and Bladder Cancer Tissues From Male Patients and Urine of Controls Using Whole Genomic Sequencing Techniques and 16S rRNA. The Aim is to Elucidate Role of Microbiota in Bladder
Status: ACTIVE_NOT_RECRUITING
Conditions: Urinary Bladder Neoplasms|Microtia
Interventions: OTHER: Urine samples and tissue samples: Samples will be collected in clean leak-proof containers without disinfectant or detergent residue and with tight-fitting leak-proof lids and preserved in a refrigera
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Semaglutide as an Adjunct to Dieting in the Treatment of Type 2 Diabetes
Status: RECRUITING
Conditions: Type2 Diabetes
Interventions: DRUG: Semaglutide, 1.34 mg/mL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect on Periodontal Markers by Bleaching Intracoronal Technique
Status: COMPLETED
Conditions: Discolored Teeth
Interventions: OTHER: Hydrogen Peroxide 35% (Opalescence Endo - Ultradent, USA)|OTHER: carbamide peroxide 37% (Whiteness Superendo, FGM, Brazil).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Lavender Oil Inhalation on Pain, Anxiety and Sleep Quality After Coronary Artery Bypass Graft
Status: UNKNOWN
Conditions: Coronary Artery Bypass Graft Surgery
Interventions: OTHER: Lavender oil inhalation will be performed by placing two drops of 2% lavender oil on a 5x5 cm sterile gauze cloth and asking the patient to smell it for three to five minutes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Using Smart Phone Application for Enhancing Adherence to Home Exercise
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: strengthening exercise program for lower-extremity muscles (knee extensor and hip abductor muscles)|OTHER: "My Dear Knee" smart phone application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Sotatercept for the Treatment of Anemia in low-or Intermediate-1 Risk Myelodysplastic Syndromes (MDS) or Non-proliferative Chronic Myelomonocytic Leukemia (CMML)
Status: COMPLETED
Conditions: Anemia|Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia|Low to Intermediate-1 MDS|Myelodysplastic Syndromes (MDS)|Chronic Myelomonocytic Leukemia (CMML)
Interventions: DRUG: Sotatercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Potassium Infusion for Conversion of Atrial Fibrillation/-Flutter
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DRUG: Potassium chloride|DRUG: Glucose 50 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Visceral Manifold Study for the Repair of Thoracoabdominal Aortic Aneurysms
Status: TERMINATED
Conditions: Thoracoabdominal Aortic Aneurysm
Interventions: DEVICE: Thoracoabdominal Aortic Aneurysm Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apixaban in Preventing Secondary Cancer Related Venous Thrombosis in Cancer Patients Who Have Completed Anticoagulation Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Vein Thrombosis|Deep Vein Thrombosis|Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm|Pulmonary Embolism|Splanchnic Vein Thrombosis
Interventions: DRUG: Apixaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of an Investigational Drug, ALN-AAT, in Healthy Adult Subjects and Patients With ZZ Type Alpha-1 Antitrypsin Deficiency Liver Disease
Status: TERMINATED
Conditions: Antitrypsin Deficiency Liver Disease
Interventions: DRUG: ALN-AAT|DRUG: Sterile Normal Saline (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Neurobiology of Suicide
Status: RECRUITING
Conditions: Healthy Volunteers|Depression
Interventions: DEVICE: Magnetic Resonance Imaging scanner, 3T|DEVICE: NeurOptics PLRTM-3000 Pupillometer|DEVICE: Experimental Anxiety Devices|DEVICE: Magnetic Resonance Imaging scanner, 7T|DRUG: Ketamine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Four Mini-screws Supported Hyrax for Maxillary Expansion in Early Adulthood
Status: ACTIVE_NOT_RECRUITING
Conditions: Transverse Maxillary Deficiency
Interventions: DEVICE: Hybrid hyrax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate Ad35-GRIN/ENV HIV Vaccine in Healthy Adult Volunteers
Status: COMPLETED
Conditions: HIV|HIV Infections
Interventions: BIOLOGICAL: Ad35-GRIN/ENV|BIOLOGICAL: Ad35-GRIN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Study of Ramucirumab (LY3009806) in Participants With Gastric or Gastroesophageal Junction (GEJ) Cancer
Status: COMPLETED
Conditions: Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Ramucirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane (TAP) Block Using Liposomal Bupivacaine in Metabolic and Bariatric Surgery Patients
Status: RECRUITING
Conditions: Morbid Obesity|Bariatric Surgery Candidate
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Study the Safety and Efficacy of Autologous Bone Marrow Stem Cells in Patients With Spinal Cord Injury
Status: UNKNOWN
Conditions: Spinal Cord Injury
Interventions: OTHER: Bone marrow derived stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Adjuvant Topotecan and Cisplatin With Concurrent Radiation Therapy for Advanced Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DRUG: Topotecan|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multisensorial IMmersive Experiences (MIME) in Disorders of Consciousness
Status: ACTIVE_NOT_RECRUITING
Conditions: Disorder of Consciousness|Acquired Brain Injury
Interventions: OTHER: MIME|OTHER: MIME + tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind, Study to Explore the Effect of GED-0301 in Subjects With Active Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: DRUG: GED-0301|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAR-20/19-T Cells in Patients With Relapsed/Refractory B Cell ALL
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia, in Relapse|Acute Lymphoblastic Leukemia With Failed Remission|Acute Lymphoblastic Leukemia Recurrent|Acute Lymphoblastic Leukemia Not Having Achieved Remission|Acute Lymphoblastic Leukemia, Pediatric|Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: CAR-20/19-T cells (5 x 10^5 CAR-20/19-T cells/kg)|BIOLOGICAL: CAR-20/19-T cells (1 x10^6 CAR-20/19-T cells/kg)|BIOLOGICAL: CAR-20/19-T cells (2.5 x10^6 CAR-20/19-T cells/kg)|BIOLOGICAL: CAR-20/19-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reproductive Health Survivorship Care Plan Pilot
Status: COMPLETED
Conditions: Breast Cancer|Hot Flashes|Vaginal Dryness|Estrogen Deprivation Symptoms
Interventions: BEHAVIORAL: Text message management prompts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Decitabine in Maintenance Therapy of Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
Status: RECRUITING
Conditions: Cutaneous Melanoma, Stage II
Interventions: PROCEDURE: Wide Local Excision = 1cm Margin|PROCEDURE: Wide Local Excision = 2cm Margin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of TL-FVP-t vs. SOC in Patients With Mild to Moderate COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Favipiravir|DRUG: Standard of care (SOC)|DRUG: standard concomitant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Dietary Supplement on Lipoprotein Lipids and Inflammatory Markers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: 300 mg/day of dietary supplement containing carrageenan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study
Status: RECRUITING
Conditions: Tuberous Sclerosis Complex|Epilepsy
Interventions: DRUG: Sirolimus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Partial Versus Complete Pulpotomy Using Three Different Materials in Primary Molars: a Clinical Study
Status: COMPLETED
Conditions: Decayed Primary Molars
Interventions: DRUG: Formocresol|DRUG: MTA|DRUG: TheraCal|PROCEDURE: pulpotomy|PROCEDURE: partial pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intensive Versus Standard Treatment for Spinal Anesthesia-induced Hypotension
Status: COMPLETED
Conditions: Outcome
Interventions: DRUG: Alpha-Agonist|OTHER: α-adrenergic receptor agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Safety and Efficacy of Osmotic Release Oral Syytem (OROS) Hydromorphone Hydrochloride (HCl) With Morphine Sustain Release (SR) in Participants With Cancer Pain
Status: TERMINATED
Conditions: Cancer Pain
Interventions: DRUG: Hydromprphone Hydrochloride (HCl) OROS|DRUG: Morphine Sustain Release (SR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of ABI-007 Plus Capecitabine as First-line Chemotherapy for Advanced Gastric Cancer Patients
Status: UNKNOWN
Conditions: Gastric Adenocarcinoma
Interventions: DRUG: nanoparticle Albumin-Bound paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate ABT-450 With Ritonavir (ABT-450/r) and ABT-267 in Japanese Adults With Chronic Hepatitis C Virus Infection
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection
Interventions: DRUG: ABT-450/ritonavir, ABT-267
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Postoperative Ketorolac on Bone Healing After Joint Fusion
Status: UNKNOWN
Conditions: Ketorolac|Joint Fusion
Interventions: PROCEDURE: great toe (1st metatarsophalangeal joint) fusion|DRUG: IV Ketorolac|DRUG: Ketorolac Pill|DRUG: 5/325mg Oxycodone-Acetaminophen|DRUG: Aspirin 81Mg Ec Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dose/ Schedule Finding Trial of Romiplostim for Chemotherapy-Induced Thrombocytopenia (CIT) in Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Lung Cancer|Chemotherapy-Induced Thrombocytopenia|Non-Small Cell Lung Cancer|Cancer|Lung Neoplasms|Oncology|Solid Tumors|Thrombocytopenia
Interventions: BIOLOGICAL: Romiplostim|DRUG: Placebo|DRUG: Gemcitabine|DRUG: Carboplatin|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Creatine Supplementation in Women With Knee Osteoarthritis and Fibromyalgia
Status: COMPLETED
Conditions: Knee Osteoarthritis|Fibromyalgia
Interventions: DIETARY_SUPPLEMENT: Creatine supplementation|DIETARY_SUPPLEMENT: Dextrose supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bronchial Trans-epithelial Transport in Patients With Idiopathic Multiple Dilations of the Bronchi
Status: COMPLETED
Conditions: Idiopathic Dilation of the Bronchi
Interventions: OTHER: bronchial ddp test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of Inactivated Varicella Zoster Virus (VZV) Vaccine in Adults With Autoimmune Disease (V212-009)
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: V212|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Berries, Bugs, and the Blues
Status: ACTIVE_NOT_RECRUITING
Conditions: Depressive Symptoms
Interventions: OTHER: Freeze-dried Blueberry Powder|OTHER: Placebo Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Vanoxerine for the Conversion of Subjects With Recent Onset Atrial Fibrillation or Flutter to Normal Sinus Rhythm
Status: TERMINATED
Conditions: Atrial Fibrillation or Flutter
Interventions: DRUG: Vanoxerine HCl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Increased Egg Consumption Have Cognitive and Neural Benefits in Food Insecure, At-risk Adolescents?
Status: COMPLETED
Conditions: Adolescents With Food Insecurity
Interventions: OTHER: Increased Egg Consumption|OTHER: Typical diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison Atomoxetine Hydrochloride and Comparator in Pediatric Outpatients With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Atomoxetine Hydrochloride|DRUG: Methylphenidate Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability and Food Effect of Sodium Valproate Minitablets in Healthy Subjects.
Status: COMPLETED
Conditions: Food-drug Interaction
Interventions: DRUG: Sodium valproate|DRUG: Sodium valproate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Patients With Refractory Dermatomyositis Using [18F] FAPI-74 PET/MRI Imaging
Status: NOT_YET_RECRUITING
Conditions: Refractory Dermatomyostitis
Interventions: DRUG: [18F]-FAPI-74
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NEXUS Study for the Treatment of de Novo Native Coronary Artery Lesions
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: CYPHER NxT SES ON BX SONIC OTW STENT DELIVERY SYSTEM (SDS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study on Safety and Efficacy of Stenting for Chronic Middle Cerebral Artery Occlusion With Limb Dysfunction
Status: COMPLETED
Conditions: Chronic Middle Cerebral Artery Occlusion|Stenting Treatment|Modified Rankin Scale|National Institutes of Health Stroke Scale
Interventions: PROCEDURE: Middle Cerebral Artery Stent Implantation|DRUG: standard treatment with aspirin.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repeat or Single Quadratus Lumborum Block for the Reduction of Opioid Prescriptions After Surgery in Retroperitoneal Sarcoma Patients ("RESQU-SARC" Trial)
Status: ACTIVE_NOT_RECRUITING
Conditions: Retroperitoneal Sarcoma
Interventions: DRUG: Liposomal Bupivacaine|DRUG: Quadratus Lumborum Block|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Safety and Effectiveness of rhTSH in Radioiodine Treatment for Patients With Differentiated Thyroid Cancer.
Status: ACTIVE_NOT_RECRUITING
Conditions: Differentiated Thyroid Cancer
Interventions: DRUG: Recombinant Human Thyroid Stimulating Hormone for Injection(rhTSH)|OTHER: radioactive iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Ability of Functional Magnetic Resonance Imaging (fMRI) to Detect and Characterize the Effects of Two Marketed Centrally Active Drugs, Placebo, and RO4917523 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: RO4917523|DRUG: escitalopram|DRUG: methylphenidate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Role of Hemostatic Powder (Endo-clotTM) in Success and Prevention of Bleeding Within Gastric Cancer Patients With Bleeding
Status: UNKNOWN
Conditions: Bleeding at Gastric Cancer
Interventions: DRUG: Endo-Clot(TM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Colorectal Cancer Patients (Stage IIIC) With Either Regorafenib or Standard of Care (No Treatment) After Adjuvant FOLFOX
Status: TERMINATED
Conditions: Colorectal Neoplasms|Adenocarcinoma of the Colon|Adenocarcinoma of the Rectum
Interventions: DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Music Intervention for Preoperative Anxiety and Acute Pain Among Mastectomy Patients
Status: COMPLETED
Conditions: Breast Cancer|Mastectomy|Pain, Postoperative
Interventions: OTHER: Music intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Automated Insulin Delivery in Adults With Advanced Kidney Disease
Status: NOT_YET_RECRUITING
Conditions: Chronic Kidney Diseases|Diabetes Mellitus
Interventions: DEVICE: Medtronic 780G System|DEVICE: Continuous Glucose Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Issue and Metabolic Characterization of Arrhythmogenic Cardiomyopathies by Hybrid PET-MRI Imaging, Impact of the Observed Profiles on the Phenotype and on the Evolution of Cardiomyopathy
Status: NOT_YET_RECRUITING
Conditions: Arrhythmogenic Cardiomyopathies
Interventions: OTHER: Biocollection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Early Postoperative Showering After Coronary Artery Bypass Grafting Using Bilateral Internal Thoracic Artery
Status: RECRUITING
Conditions: Wounds and Injuries|Wound Infection
Interventions: BEHAVIORAL: Early shower
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Confirmatory Study of K-237
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: K-237 0.3-0.4mg/kg (once daily)|DRUG: Placebo 0.3-0.4mg/kg (once daily)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of FTY720 on Pulmonary Function in Patients With Moderate Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: FTY720|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Theory Based Integrated Program on Medication Adherence Among Community Dwelling Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Medication Adherence|Medication Compliance
Interventions: BEHAVIORAL: The theory based integrated program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Efficacy of PanCytoVir™ for the Treatment of Non-Hospitalized Patients With COVID-19 Infection
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: PanCytoVir™ (probenecid)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessing Colonic Folate Absorption & Metabolism
Status: ACTIVE_NOT_RECRUITING
Conditions: Folate
Interventions: DIETARY_SUPPLEMENT: Folic Acid supplementation|DIETARY_SUPPLEMENT: Adult Multivitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Exergame Balance Training for Patients With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: OTHER: Low complexity Exergaming group|OTHER: Moderate complexity Exergaming group|OTHER: High complexity Exergaming group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resistance Exercise and Knee Osteoarthritis Pain, Functional Impairment and Cartilage Turnover
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: normal activities and clinical care|OTHER: Concentric Focused Resistance Exercise|OTHER: Eccentric Focused Resistance Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Study of ATrial Strain and Voltage by High Density Mapping in Young Patients With Atrial Fibrillation.
Status: NOT_YET_RECRUITING
Conditions: Paroxysmal Atrial Fibrillation|Persistent Atrial Fibrillation|Catheter Ablation|Atrial Cardiomyopathy
Interventions: DIAGNOSTIC_TEST: MRI (with injection of contrast product)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Soy Based Dietary Supplements on Cardiometabolic Risk Factors.
Status: COMPLETED
Conditions: Obesity|Cardiovascular Risk Factors
Interventions: DIETARY_SUPPLEMENT: Luna Rich X|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Reliv Now
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of TAP Block for Postoperative Pain Control After Varicocele Operations.
Status: COMPLETED
Conditions: Varicocele
Interventions: PROCEDURE: TAP block group (Group T)|PROCEDURE: spinal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Acute Effectiveness of Additional Drugs to the Standard Treatment of Depression
Status: COMPLETED
Conditions: Bipolar Disorder|Depressive Disorder
Interventions: DRUG: buproprion (Wellbutrin)|DRUG: sertraline (Zoloft)|DRUG: venlafaxine (Effexor)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Glucose Transporter Type I Deficiency (G1D) Registry
Status: RECRUITING
Conditions: GLUT1 Deficiency Syndrome|Glucose Transporter Type 1 Deficiency Syndrome|Glucose Transporter type1 (GLUT-1) Deficiency|GLUT-1 Deficiency Syndrome
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Erector Spinae Plane Block (ESPB) Versus Quadratus Lumborum Block (QLB) for Postoperative Analgesia After Caesarean Section
Status: COMPLETED
Conditions: Pain, Post Operative|Cesarean Section Complications|Anesthesia, Local|Obstetric Anesthesia Problems
Interventions: PROCEDURE: ESPB
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: On-site Supportive Communication Training in Doctor-patient Communication
Status: COMPLETED
Conditions: Communication Programs|Communication, Manual|Communication Research|Oncology|Doctor Patient Relation|Job Stress|Burnout|Satisfaction, Patient|Efficacy, Self
Interventions: BEHAVIORAL: On-site supportive communication training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study on the Biobehavioral Mechanisms of Baclofen and Alcohol Drinking
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: Baclofen|DRUG: Cyproheptadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Weekly Topotecan in Combination With Carboplatin in Two Different Schedules for Refractory and/or Advanced Solid Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Topotecan|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Eye and Body Training on the Injury Rate of Concussions in Female Soccer Players
Status: NOT_YET_RECRUITING
Conditions: Concussion, Brain|Musculoskeletal Pain
Interventions: OTHER: Training recommendation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Adjuvanted Hepatitis B Vaccine to Double Dose of Engerix™-B in Pre- /Haemodialysis Patients Aged ≥15 Years
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: Hepatitis B adjuvanted vaccine|BIOLOGICAL: Engerix-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Capecitabine and Lapatinib Ditosylate With or Without Cixutumumab in Treating Patients With Previously Treated HER2-Positive Stage IIIB-IV Breast Cancer
Status: COMPLETED
Conditions: HER2 Positive Breast Carcinoma|Recurrent Breast Carcinoma|Stage IIIB Breast Cancer AJCC v7|Stage IIIC Breast Cancer AJCC v7|Stage IV Breast Cancer AJCC v6 and v7
Interventions: DRUG: Capecitabine|BIOLOGICAL: Cixutumumab|DRUG: Lapatinib Ditosylate|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration
Status: NOT_YET_RECRUITING
Conditions: THC|Cannabis|Cannabis Use|Cannabis Smoking|Tobacco Use|Vaping
Interventions: DRUG: Cannabis|DRUG: Nicotine|DEVICE: Pax Loose Leaf Vaporizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Assess Gonorrhoeae Immune Responses Induced by a N. Meningitidis Vaccine
Status: COMPLETED
Conditions: Neisseria Gonorrhoeae Infection
Interventions: BIOLOGICAL: Meningococcal Group B Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Voclosporin to Treat Active Noninfectious Uveitis
Status: COMPLETED
Conditions: Noninfectious Uveitis
Interventions: DRUG: LX211
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Normovolemic Hemodilution in Off-pump CABG
Status: UNKNOWN
Conditions: Acute Normovolemic Hemodilution|Off-Pump Coronary Artery Bypass Surgery
Interventions: PROCEDURE: Acute normovolemic hemodilution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mentholyptus Drops on the Palatability of PEG-Electrolyte Solution
Status: COMPLETED
Conditions: Colon Cancer
Interventions: OTHER: PEG solution (Fortrans®) and Mentholyptus Drops (Halls®)|OTHER: PEG solution (Fortrans®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Simufilam 100 mg for Mild-to-Moderate Alzheimer's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: Simufilam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guıded Adductor Canal Block vs Perıcapsular Nerve Group Block in Knee Artroplasty
Status: RECRUITING
Conditions: Knee Disease|Knee Osteoarthritis|Knee Arthropathy
Interventions: DRUG: Adductor canal block|DRUG: PENG block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Orofacial Pain and PropRANOlol
Status: COMPLETED
Conditions: Temporomandibular Disorders
Interventions: DRUG: Propranolol ER|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Versus Late Upper Extremity Mobilization After Meshed / Sheet Split Thickness Skin Autograft on Wound Healing in Adult Burn Patients
Status: NOT_YET_RECRUITING
Conditions: Burns
Interventions: PROCEDURE: Early Mobilization|PROCEDURE: Late Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventive Sodium Lactate and Traumatic Brain Injury
Status: COMPLETED
Conditions: Head Trauma
Interventions: DRUG: half molar sodium lactate|DRUG: isotonic sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitively Enriched Walking Program
Status: RECRUITING
Conditions: Healthy Aging|Cognitive Decline|Physical Inactivity
Interventions: BEHAVIORAL: Cognitively enriched walking program|BEHAVIORAL: walking program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Digital Breast Tomosynthesis + Standard 2- Dimensional Mammography in Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: 2-dimensional mammogram|DEVICE: digital breast tomosynthesis (DBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Diagnosing and Targeting Mechanisms of Diuretic Resistance in Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Increased Intravenous Bolus Loop Diuretic Dose (Bumetanide or Furosemide)|DRUG: IV Chlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Cognitive Behavioural Therapy and Exercise on Stress and Cognitive Deficits in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Cognitive Deficits|Stress, Psychological
Interventions: BEHAVIORAL: Cognitive Behavioural Therapy|BEHAVIORAL: Aerobic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Precise Positioning and Intelligent Operation of Surgical Robots to Reconstruct Cruciate Ligaments
Status: UNKNOWN
Conditions: Cruciate Ligament Rupture
Interventions: DEVICE: Arthroscopic surgical robot|DEVICE: Conventional arthroscopic cruciate ligament reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ioflupane I123 (DaTSCAN) and Positron Emission Tomography-computed Tomography Fludeoxyglucose (PET-CT FDG) to Assess Brain Function of Parkinson Patients With Different Genetic Characteristics
Status: UNKNOWN
Conditions: Parkinson Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Dose of Erythropoietin Analogue After Cardiac Arrest
Status: COMPLETED
Conditions: Comatose Survivors of Cardiac Arrest
Interventions: DRUG: EPOETINE ALPHA|OTHER: Control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Potential Interaction Between Telaprevir and Methadone, at Steady-State
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Telaprevir|DRUG: Methadone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigate the Effect of Neramexane Mesylate IR Tablet on Driving Fitness and Capability to Operate Machines in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Neramexane mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Dexmedetomidine Combined With Ropivacaine for Postoperative Continuous Femoral Nerve Block
Status: SUSPENDED
Conditions: Elderly|Knee Arthroplasty|Nerve Block|Dexmedetomidine|Postoperative Delirium|Long-term Outcome
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reactogenicity, Safety, and Immunogenicity of a Live Monovalent H5N2 Influenza Vaccine
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: LAIV H5N2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intravenous (IV) Solutions for Dehydration in Children With Gastroenteritis
Status: TERMINATED
Conditions: Dehydration|Gastroenteritis
Interventions: DRUG: multiple electrolyte solution|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Celecoxib as Add-on Therapy to Risperidone Versus Risperidone Alone in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Celecoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mandibular Vertical Height Augmentation in Segmental Defects Using Combined Vascularized and Non-Vascularized Fibula Flap
Status: UNKNOWN
Conditions: Mandibular Reconstruction Using Free Fibula Flap
Interventions: PROCEDURE: Mandibular vertical height augmentation in segmental defects using combined vascularized and non-vascularized fibula flap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block vs. Usual Care for ED Patients With Mechanical Back Pain
Status: COMPLETED
Conditions: Back Pain
Interventions: PROCEDURE: Erector Spinae plane block using 20 ml of bupivicaine 0.25%|DRUG: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tocotrienols in Parkinson's Disease (PD)
Status: RECRUITING
Conditions: Neuro-Degenerative Disease|Parkinson Disease
Interventions: DRUG: Tocovid Suprabio (HOV-12020)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 24-hour Mifepristone and Buccal Versus Mifepristone and Vaginal Misoprostol for Cervical Preparation for D&E
Status: COMPLETED
Conditions: Abortion, Second Trimester
Interventions: DRUG: Vaginal Misoprostol|DRUG: Buccal Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody Therapy Against Chronic Herpes Simplex Virus 1 Infection
Status: TERMINATED
Conditions: Herpes Labialis
Interventions: DRUG: HDIT101 (blinded therapy)|DRUG: Placebo (blinded therapy)|BEHAVIORAL: Photo documentation of orolabial herpes lesions|BEHAVIORAL: Completion of questionnaires (patient-reported outcomes)|PROCEDURE: 28-day swabbing of orolabial region|PROCEDURE: Blood drawings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effectiveness of SPAir-Q Among Different Age Groups
Status: NOT_YET_RECRUITING
Conditions: Oropharyngeal Leak Pressure (OLP)|LMA Insertion Time|Ease of LMA Placement|Maneuvers Required for Successful Ventilation|Gastric Insufflation|Fiberoptic View Grading|Ventilation Problems|Post Operative Complications|Post Operative Complications at the First and Twenty-fourth Hour Related to SP Air-Q
Interventions: OTHER: Group 1 will include patients aged 18-40 years|OTHER: Group 2 will include patients aged 40-64 years|OTHER: Group 3 will include patients aged 65-85 years
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety And Efficacy of BIBF 1120 in Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Pulmonary Fibrosis
Interventions: DRUG: low dose BIBF1120 once daily|DRUG: low dose BIBF 1120 twice daily|DRUG: intermediate dose BIBF 1120 twice daily|DRUG: high dose BIBF 1120 twice daily|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Myofascial Release Technique On Respiratory Parameters in Subjects With Short Hamstring Muscle
Status: COMPLETED
Conditions: Hamstring Contractures
Interventions: OTHER: Myofascial Release Technique|OTHER: Sham-Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Feasibility of Outpatient Daily High Dose Cytarabine as Consolidation Therapy for Older Patients With Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Cytosine Arabinoside
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effıcıency Of Hybrıd Based Sımulatıon Method In Breastfeedıng Educatıon
Status: ACTIVE_NOT_RECRUITING
Conditions: Breastfeeding|Training Group, Sensitivity|High Fidelity Simulation Training|Medical Simulation|Standardized Patient
Interventions: OTHER: hiybrid simulation|OTHER: control grup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PRISM for Depression and Anxiety in Young Adults With Cancer
Status: NOT_YET_RECRUITING
Conditions: Cancer Diagnosis|Non-Metastatic Neoplasm|Anxiety|Anxiety Disorders|Depression|Depressive Disorder|Depression, Anxiety
Interventions: BEHAVIORAL: Promoting Resilience in Stress Management Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial of Standard Versus Goal-Directed Perioperative Fluid Management (GDT) for Patients Undergoing Liver Resection
Status: COMPLETED
Conditions: Liver Cancer
Interventions: PROCEDURE: Standard fluid management|DEVICE: Goal directed fluid therapy with the Edwards EV1000 system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Implantation of the Cochlear™ Nucleus® Hybrid S Round Window (S-RW) in Adults
Status: COMPLETED
Conditions: Sensorineural Hearing Loss
Interventions: DEVICE: Hybrid SRW cochlear implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Effectiveness of the Laminar Left Atrial Appendage Closure System
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: Left Atrial Appendage Closure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 2-Year Post-Approval Study to Investigate the Scandinavian Total Ankle Replacement System (STAR) Ankle Under Actual Conditions of Use
Status: COMPLETED
Conditions: Primary Arthrosis|Post Traumatic Arthritis|Rheumatoid Arthritis|Osteoarthritis
Interventions: DEVICE: Scandinavian Total Ankle Replacement System (STAR Ankle)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Suprainguinal Fascia Iliaca Compartment Block for Analgesia After Total Hip Arthroplasty
Status: COMPLETED
Conditions: Arthritis of Hip
Interventions: DRUG: 0.5% Ropivacaine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Steroid Injections Given at the "Level of MRI Pathology" Versus at the "Level of Clinical Symptoms" to See if One is More Effective Than the Other.
Status: WITHDRAWN
Conditions: Radiculopathy|Spinal Stenosis|Intervertebral Disc Displacement
Interventions: PROCEDURE: Transforaminal Epidural Steroid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: DIAGNOSTIC