pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Intraoperative Colonic Irrigation Versus Stent Placement in Obstructive Left-Sided Colonic Cancer
Status: TERMINATED
Conditions: Colon Neoplasm|Colorectal Surgery|Intestinal Obstruction
Interventions: PROCEDURE: intraoperative colon lavage with primary anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study Comparing The Safety, Tolerability and Efficacy of Trizivir VS Combivir & Atazanavir In Subjects With HIV
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus I|HIV Infection
Interventions: DRUG: Trizivir|DRUG: atazanavir|DRUG: Combivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: GnRH Analogue for Ovarian Function Preservation in Hematopoietic Stem Cell Transplantation Patients
Status: COMPLETED
Conditions: Amenorrhea|Premature Ovarian Failure|Ovarian Function Insufficiency
Interventions: DRUG: Leuprolide Acetate|BEHAVIORAL: Questionnaire|PROCEDURE: Hematopoietic Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Engaging Men in Weight Loss With a Game-based mHealth and Neurotraining Program
Status: RECRUITING
Conditions: Obesity|Weight Loss
Interventions: BEHAVIORAL: Gamified behavioral weight loss treatment|BEHAVIORAL: mHealth behavioral weight loss treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Mesenchymal Stem Cells for the Treatment of Medically Refractory Ulcerative Colitis (UC)
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: DRUG: Remestemcel-L|DRUG: Remestemcel-L|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Additive Intra-ocular Pressure Reduction Effect of Fixed Combination of Maleate Timolol 0.5%/Dorzolamide 2% on Monotherapy With Latanoprost in Patients With Elevated Intra-ocular Pressure
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: latanoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Near-Infrared Spectroscopy (fNIRS) Assessing Neural Activity During Virtual Reality Walking Intervention
Status: NOT_YET_RECRUITING
Conditions: Traumatic Brain Injury
Interventions: DEVICE: Motek C-Mill™ treadmill|OTHER: training session with and without VR wearing the fNIRS cap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Single Cell Immune and Non-immune Correlates of Response to Neoadjuvant Abemaciclib
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Letrozole|DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Glossopharyngeal Nerve Block on Pharyngeal Dysphagia Induced by Gastroesophageal Reflux Disease
Status: WITHDRAWN
Conditions: Dysphagia
Interventions: BEHAVIORAL: Rehabilitation therapy|PROCEDURE: Glossopharyngeal Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Home-based Occupational Therapy Tele-rehabilitation for Outpatients After Hip Fracture Surgery
Status: COMPLETED
Conditions: Telerehabilitation
Interventions: BEHAVIORAL: Caspar Telerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Low-dose Adjunctive alTeplase During prIMary PCI
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Alteplase|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sugar-Free Chewing Gum Containing Tulsi Extract on Salivary Streptococcus Mutans in a Group of Children
Status: COMPLETED
Conditions: Dental Caries in Children
Interventions: DIETARY_SUPPLEMENT: Tulsi Gum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Short Course Terlipressin for Control of Acute Variceal Bleeding
Status: COMPLETED
Conditions: Hemorrhage|Esophageal Varices|Portal Hypertension
Interventions: DRUG: Terlipressin|DRUG: Terlipressin & then Dummy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Into the Future Cardiovascular Disease (CVD) Risk of Phenylketonuria (PKU) Patients on a Low Phenylalanine Treatment Diet (LPD).
Status: UNKNOWN
Conditions: Phenylketonurias|Cardiovascular Diseases
Interventions: DIAGNOSTIC_TEST: Carotid intima media thickness measurement (CIMT)|DIAGNOSTIC_TEST: Pulse Wave Velocity measurement|DIAGNOSTIC_TEST: Ankle-brachial pressure index (ABPI)|OTHER: Diet questionnaire and diet diary|OTHER: Routine blood samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mean Arterial Pressure Reduction Anesthesia Induction Using Propofol Bolus or Tritiated Target-infusion
Status: UNKNOWN
Conditions: Hypotension on Induction|Hypnotic Intoxication
Interventions: DRUG: Propofol|DRUG: Propofol Injection [Diprivan]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Emails Promoting COVID-19 Vaccination Among Healthcare Workers
Status: COMPLETED
Conditions: Vaccination Refusal|Communication
Interventions: BEHAVIORAL: Social Proof|BEHAVIORAL: Reframing|BEHAVIORAL: Scarcity Message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Prophylactic Preoperative HIPEC in Advanced Gastric Cancer at High Risk of Peritoneal Recurrence
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: COMBINATION_PRODUCT: FLOT + HIPEC + Surgery|COMBINATION_PRODUCT: FLOT + Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety of Rabies Vaccine, Administered With Two Different Simulated Post Exposure Schedules
Status: COMPLETED
Conditions: Rabies
Interventions: BIOLOGICAL: Purified Chick Embryo Cell Inactivated Rabies Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Individual Reminiscence Therapy in the Elderly People With Neurocognitive Disorders
Status: COMPLETED
Conditions: Dementia|Neurocognitive Disorders|Cognitive Impairment|Cognitive Dysfunction|Cognitive Decline
Interventions: OTHER: Reminiscence therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adipose Dysfunction, Imaging, Physiology, and Outcomes With Sodium Glucose Cotransporter 2 Inhibitor (SGLT2i) for Sleep Apnea: The ADIPOSA Study
Status: RECRUITING
Conditions: Sleep Apnea
Interventions: DRUG: Bexagliflozin 20 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Infectious Complications After Cystectomy: A Prospective Observational Study
Status: RECRUITING
Conditions: Bladder Cancer|Infections|Infection, Bacterial|Infection, Hospital|Infection Wound|Urinary Tract Infections|Urinary Bladder Diseases|Urinary Tract Disease
Interventions: PROCEDURE: Cystectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Conversion From Cyclosporine to Tacrolimus on the Changes of Cardiovascular Risk Profiles and Serum Metabolites in Renal Transplant Recipients
Status: UNKNOWN
Conditions: CYCLOSPORINE/TACROLIMUS
Interventions: DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-angiogenesis Agent AG-013736 in Patients With Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Neoplasms|Carcinoma, Non-small Cell Lung
Interventions: DRUG: axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clozapine-induced Hypersalivation - Feasibility Trial
Status: COMPLETED
Conditions: Sialorrhea
Interventions: DRUG: Hyoscine|DRUG: Glycopyrrolate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epidemiology and Diagnosis of Haemoptysis: a Multicenter Study
Status: COMPLETED
Conditions: Lung Cancer|Tuberculosis|Bronchiectasis|Pneumonia|Acute Bronchitis|Chronic Obstructive Pulmonary Disease|Cryptogenic Haemoptysis
Interventions: OTHER: Chest X-ray|OTHER: computed tomography of the chest|PROCEDURE: Bronchoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Lumasiran in Infants and Young Children With Primary Hyperoxaluria Type 1
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Hyperoxaluria|Primary Hyperoxaluria Type 1 (PH1)
Interventions: DRUG: Lumasiran
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Concurrent Ultra-Low-Dose Total-Skin Electron Beam Therapy and Brentuximab Vedotin Given Quarterly Over 12 Months for Patients With Mycosis Fungoides
Status: RECRUITING
Conditions: Mycosis Fungoides
Interventions: DRUG: Brentuximab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of LPPRP in the Treatment of Chondromalacia Patella
Status: COMPLETED
Conditions: Chondromalacia Patellae
Interventions: BEHAVIORAL: Exercise|BIOLOGICAL: LP-PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pivotal Study in HER2 Negative, Locally Recurrent or Metastatic Breast Cancer
Status: TERMINATED
Conditions: Metastatic Breast Cancer|Locally Recurrent Breast Cancer
Interventions: DRUG: Eribulin|DRUG: Balixafortide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stabilization of Fresh Unilateral Unstable Pertrochanteric Hip Fracture
Status: UNKNOWN
Conditions: Unilateral Unstable Hip
Interventions: DEVICE: Endovis BA2 nail|DEVICE: Dynamic Hip Screw (DHS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RCT Protocol for 'OverThinking': A Mobile EMI for Reducing Experiential Avoidance
Status: NOT_YET_RECRUITING
Conditions: Depression|Anxiety|Rumination
Interventions: BEHAVIORAL: OverThinking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Genetic Factors and Interrelationships for Sexual Orientation, Susceptibility to HIV and Kaposi's Sarcoma, Alcoholism and Psychological Traits, and Histocompatibility Antigens
Status: COMPLETED
Conditions: Alcoholism|HIV Infection|Homosexuality|Kaposi's Sarcoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prolonged Release Pirfenidone Versus Placebo in Compensated Cirrhosis.
Status: COMPLETED
Conditions: Liver Fibrosis|Cirrhosis, Liver|Chronic Liver Disease
Interventions: DRUG: Pirfenidone 1200 mg|DRUG: Pirfenidone 1800 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Hydrochloride in Treating Patients With Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Duct Cell Adenocarcinoma of the Pancreas|Stage III Pancreatic Cancer|Stage IV Pancreatic Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: fluorouracil|RADIATION: radiation therapy|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Valvuloplasty Scoring Balloon Catheter First-in-Man Study
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: AngioScore's Valvuloplasty Scoring Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Favipiravir 200 mg Film Tablet (ATABAY, Turkey) Under Fasting Conditions
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: FAVICOVIR 200 mg Film Tablet|DRUG: AVIGAN 200 mg Film Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Strategies for Electrical Isolation of Pulmonic Veins for Curative Treatment of Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Pulmonary Vein Isolation (Radiofrequency Catheter Ablation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antihypertensive Effectiveness of the Associations of Hydrochlorothiazide and Amiloride and Hydrochlorothiazide and Enalapril
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Amiloride 2,5/d or Enalapril/d 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Immunogenicity, Safety, and Tolerability of VARIVAX™ Manufactured With a New Process (V210-062)
Status: WITHDRAWN
Conditions: Varicella
Interventions: BIOLOGICAL: VARIVAX™ VEP|BIOLOGICAL: VARIVAX™ 2007 Process|BIOLOGICAL: M-M-R™ II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Comparing Etanercept and Methotrexate vs. Methotrexate Alone in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Etanercept|DRUG: Methotrexate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Steroid Combination Compared With Individual Administration in the in the Treatment of Ocular Inflammation and Infection
Status: WITHDRAWN
Conditions: Ocular Inflammation|Infection Associated Blepharitis|Keratitis|Conjunctivitis, Bacterial
Interventions: DRUG: azithromycin 1.5%/Loteprednol 0,5% + placebo|DRUG: azithromycin 1.5% + Loteprednol 0,5% (separately)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pyronaridine-artesunate and Artemether-lumefantrine for the Treatment of Paediatric Malaria
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Pyronaridine-artesunate|DRUG: Artemether-lumefantrine combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intra-vaginal Conjugated Estrogen Cream on Ring Pessary Use for Pelvic Organ Prolapse
Status: UNKNOWN
Conditions: Pelvic Floor Prolapse
Interventions: DRUG: Vaginal Cream with Applicator [Dose Form]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Supraclavicular Brachial Plexus Block, Volume Comparison of Local Anaesthetics and Diaphragmatic Motility.
Status: UNKNOWN
Conditions: Sucessful Block With Less Hemidiaphragmatic Paresis in Distal Upper Arm Fracture
Interventions: PROCEDURE: ultra sound guided supraclavicular brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Midline Catheter Versus Long Peripheral Intravenous Catheter in Hospitalized Adult Patients
Status: RECRUITING
Conditions: Vascular Access Devices
Interventions: DEVICE: PowerGlide Pro Midline catheter.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Novel Role of Alpha Lipoic Acid in Comparison With Selenium in Mitochondrial Resuscitation and miRNA-126 Expression in Hemodialysis Patients
Status: COMPLETED
Conditions: Antioxidative Stress|End Stage Renal Disease on Dialysis
Interventions: DRUG: Alpha lipoic acid|DRUG: Selenium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Bioavailability of Risankizumab Following Subcutaneous Dosing in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: risankizumab|DRUG: risankizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Overlooked Population at Risk for AIN.
Status: COMPLETED
Conditions: High Grade Cervical Dysplasia|Cervical Cancer
Interventions: PROCEDURE: Screening Anal Pap Smear - No High Resolution Anoscopy|PROCEDURE: Screening Anal Pap Smear - With High Resolution Anoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Straining Techniques on Women and Newborn
Status: COMPLETED
Conditions: Prolonged Second Stage of Labor|Other Specified Trauma to Perineum and Vulva During Delivery|Newborn; Vitality
Interventions: OTHER: Straining types
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: HiFIT Study : Hip Fracture: Iron and Tranexamic Acid
Status: TERMINATED
Conditions: Hip Fractures Pathologic|Anemia
Interventions: DRUG: Iron Isomaltoside 1000|DRUG: Tranexamic Acid|DRUG: Placebos iron isomaltoside 1000|DRUG: Placebos tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Investigate the Efficacy and Safety of Sitravatinib in Combination With Tislelizumab in Participants With Esophageal Squamous Cell Carcinoma
Status: TERMINATED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Sitravatinib|DRUG: Tislelizumab|DRUG: Docetaxel|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Imaging for Diagnostic of Amyotrophic Lateral Sclerosis
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis With Dementia
Interventions: DIAGNOSTIC_TEST: Whole Body MRI and ENMG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Does Deep Neuromuscular Blockade Improve Operating Conditions During Total Hip Replacements?
Status: COMPLETED
Conditions: Arthropathy of Hip
Interventions: DRUG: Vecuronium 0.1 mg/kg|DRUG: Vecuronium 0.2mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of a Ready Made Plastic Stent With Apically Repositioned Flap in Augmentation of the Peri Implant Soft Tissue
Status: COMPLETED
Conditions: Loss of Keratinized Gingiva Around Dental Implants
Interventions: DEVICE: ready made plastic stent application|PROCEDURE: simple interrupted sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial Measuring the Effect of Decision Aids on Patients' Satisfaction, Conflict of Decision-making and Clinical Outcome
Status: SUSPENDED
Conditions: Trapeziometacarpal Arthrosis|Carpal Tunnel Syndrome|Cubital Tunnel Syndrome|Distal Radius Fractures|Trigger Finger
Interventions: BEHAVIORAL: Decision Aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Clinical Outcomes in Ziemer Femtosecond Versus Conventional Phacoemulsification Surgery
Status: UNKNOWN
Conditions: Visual Outcomes
Interventions: PROCEDURE: Femtosecond laser assisted cataract surgery|PROCEDURE: Conventional phacoemulsification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Determine Biomarkers of Response to a Gamma Secretase Inhibitor
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: MK0752|DRUG: Comparator: MK0752.|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Trial to Examine Effects of Atomoxetine in the Treatment of Negative Symptoms in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Atomoxetine (Strattera)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Combination of Benazepril Plus Hydrochlorothiazide in Chinese Patients With Mild to Moderate Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Benazepril plus hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Pharmacokinetics and Pharmacodynamics of RO7234292 (RG6042) in CSF and Plasma, and Safety and Tolerability Following Intrathecal Administration in Patients With Huntington's Disease
Status: COMPLETED
Conditions: Huntingtons Disease
Interventions: DRUG: RO7234292 (RG6042)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Infective Risk, Efficacy of Bacterial Prophylaxis and Validation of Sepsis Scores NEWS (National Early Warning Score) and qSOFA (Quick Sequential Organ Failure Assessment) in Patient With Acute Myeloid Leukemia Treated With Intensive Chemotherapy
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultra-protective Pulmonary Ventilation Supported by Low Flow ECCO2R for Severe ARDS
Status: TERMINATED
Conditions: Respiratory Distress Syndrome, Adult
Interventions: DEVICE: Prismalung|OTHER: Ultra-protective ventilation|OTHER: Conventional Lung Protective Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention on Modifiable Lifestyle Risk Factors for Dementia Prevention
Status: COMPLETED
Conditions: Risk Behavior|Cognitive Decline
Interventions: BEHAVIORAL: Cognitive Engagement Group|BEHAVIORAL: Physical Activity Group|BEHAVIORAL: Diet Group|BEHAVIORAL: Multimodal group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mobile Application to Improve Nutritional Counseling Provided by Primary Care Physicians for Hypertension.
Status: COMPLETED
Conditions: Hypertension
Interventions: OTHER: telehealth|OTHER: nutritional counseling|DEVICE: smartphone (mobile app)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Data Acquisition Study for a Communication Device for Pediatric Patients With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DEVICE: Dynavox Maestro|DEVICE: Experimental App
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Microcrystalline Titanium Dioxide With Covalently Linked Monovalent Silver Ions on Complications After Total Hysterectomy ( ISTIAB-0)
Status: UNKNOWN
Conditions: Infection|Bleeding|Complication, Postoperative
Interventions: DRUG: TIAB: microcrystalline titanium dioxide with covalently linked monovalent silver ions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Lefamulin to Moxifloxacin for the Treatment of Adults With Pneumonia
Status: COMPLETED
Conditions: Community Acquired Pneumonia
Interventions: DRUG: lefamulin|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Inflammasome in Inflammatory Macrophage in Mycobacterium Avium Complex-lung Disease and Mycobacterium Abscessus-lung Disease
Status: UNKNOWN
Conditions: To Investigate the Inflammasome Response of Inflammatory and Resting Macrophage|To Compare the Difference of Inflammasome Response of Inflammatory Macrophage|To Study the Diagnostic Aid From Immunological Markers in Inflammasome Response
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Study Investigating Nic's Keto Diet on Cardiovascular Health in Healthy Adults With Mildly Elevated LDL Levels
Status: COMPLETED
Conditions: Ketogenic Dieting|Healthy
Interventions: OTHER: Nic's Keto Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: mTBI Mechanisms of Action of HBO2 for Persistent Post-Concussive Symptoms
Status: COMPLETED
Conditions: Traumatic Brain Injury With Brief Loss of Consciousness|Post-Concussion Syndrome
Interventions: DRUG: Hyperbaric oxygen (HBO2) at 1.5 atms|DRUG: Sham control 1.2 atms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: What is the Dose Response of Varying Meal Content of Fat on Postprandial Glycaemia in Children With T1DM?
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: OTHER: Test drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of USP Methylene Blue on Cognitive and fMRI Brain Activity
Status: COMPLETED
Conditions: Brain Activity
Interventions: DRUG: Methylene Blue (USP grade, 280mg oral)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: CD 70 CAR T for Patients With CD70 Positive Malignant Hematologic Diseases
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Non-hodgkin's Lymphoma|Multiple Myeloma
Interventions: BIOLOGICAL: CD70 CAR T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modification of Chronic Inflammation by Inhaled Carbon Monoxide in Patients With Stable Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: carbon monoxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Rollover Study to Provide Continued Treatment With GSK2118436 to Subjects With BRAF Mutation-Positive Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: GSK2118436|DRUG: GSK1120212|DRUG: Other approved anti-cancer agent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: APatinib Plus Chemotherapy vErsus Chemotherapy As First-line Treatment for Advanced NSCLC
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Apatinib|DRUG: Pemetrexed|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Evidence to the Consumption of Lactobacillus GG and FOS Consumption in Patients With Herpes Labialis
Status: COMPLETED
Conditions: Herpes Labialis
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Prebiotics and Probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Transversus Abdominis Plane Block for Analgesia After Abdominoplasty
Status: COMPLETED
Conditions: Abdominoplasty|Transversus Abdominis Plane (TAP) Block
Interventions: PROCEDURE: TAP Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Innate Host Immune Response to C. Glabrata Clinical Isolates Resistant to Echinocandins: Impact on the Management of Candidemia in High-risk Patients
Status: UNKNOWN
Conditions: Candidemia of C. Glabrata
Interventions: OTHER: in vitro evaluation of epithelial immune response during C. glabrata infection|OTHER: study of the impact of resistance phenotype acquisition on the virulence of C. glabrata isolates
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Novel Therapeutic Target for Alzheimer's Disease in Men and Women 50-85 Years of Age.
Status: UNKNOWN
Conditions: Mild Cognitive Impairment|Mild Alzheimer's Disease
Interventions: DRUG: Dabigatran|DRUG: Placebo - Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intranasal Steroid as Medical Therapy For Sleep-Disordered Breathing in Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Sleep Disorder; Breathing-Related|Snoring|Obstructive Sleep Apnea of Child|Sleep Disorders in Children|Tonsillar Hypertrophy|Adenoidal Disorder
Interventions: DRUG: Mometasone Furoate 50mcg Nasal Spray|DRUG: Sodium Chloride 0.9 % Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2a Study to Evaluate the Efficacy and Safety of MEDI9929 in Adults With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: MEDI9929|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Assess the Safety and Preliminary Efficacy of HCR040 in Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome
Interventions: DRUG: HCR040 (Phase 1)|DRUG: Placebo (Phase 2)|DRUG: HCR040 (Phase 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NHLBI DIR LAMPOON Study: Intentional Laceration of the Anterior Mitral Leaflet to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Implantation
Status: COMPLETED
Conditions: Mitral Valve Failure
Interventions: DEVICE: Edwards SAPIEN 3 transcatheter heart valve|DEVICE: ASHI INTECC Astato XS 20
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Role of Intra-articular Injections of Platelet Rich Plasma (PRP) in Patients With Rheumatoid Arthritis.
Status: UNKNOWN
Conditions: RA - Rheumatoid Arthritis
Interventions: PROCEDURE: PRP intra articular injection|PROCEDURE: NACL intra articular injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet-based Interacting Together Everyday, Recovery After Childhood TBI (I-InTERACT)--RRTC
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: Internet-based Interacting Together Everyday: Recovery After Childhood TBI (I-InTERACT)|BEHAVIORAL: Internet-based-Interacting Together Everyday, Recovery after Childhood TBI Express (I-InTERACT Express)|BEHAVIORAL: Internet Resources Comparison (IRC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Individualized Stepwise Treatment Mode of Adolescent Idiopathic Scoliosis
Status: RECRUITING
Conditions: Adolescent Scoliosis
Interventions: PROCEDURE: Conventional treatment|BEHAVIORAL: intervention treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-Modality Therapy for Untreated Patients With Resectable or Marginally Resectable Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: OTHER: Multi-Modality; IORT, Surgery, Radiation, Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TQ-B3525 Tablets Combined With Osimertinib Mesylate Tablets in the Treatment of Advanced Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Nonsmall-cell Lung Cancer
Interventions: DRUG: TQ-B3525 Tablets, Osimertinib Mesylate Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Postoperative Ocular Surface Changes and Intervention Effect After PPV in MGD Dry Eye Patients
Status: COMPLETED
Conditions: Meibomian Gland Dysfunction of Unspecified Eye, Unspecified Eyelid
Interventions: DRUG: Routine preoperative and postoperative anti-infection therapy|DRUG: artificial tear therapy|PROCEDURE: Cleaning, hot compresses and massage of the meibomian gland
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Local Analgesia for Postoperative Analgesia in Posterior Thoracolumbar Operation
Status: COMPLETED
Conditions: Pain
Interventions: OTHER: local|OTHER: intravenous|DRUG: 0.33% ropivacaine 250ml|DRUG: flurbiprofen axetil 150mg,palonosetron 0.5mg,pentazocine 240mg.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contrast Enhanced Endoscopic Ultrasound in Pancreas Lesions
Status: RECRUITING
Conditions: Pancreatitis|Pancreas Cancer|Pancreas Cyst
Interventions: DRUG: EUS enhanced with contrast to evaluate pancreas
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Coaching Program to Address Burnout, Wellness and Professional Development in Early Career Pediatric Surgeons
Status: COMPLETED
Conditions: Well-Being, Psychological|Surgical Residents|Burnout, Professional
Interventions: BEHAVIORAL: Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Goal Directed Haemodynamic Treatment for Patients With Proximal Femoral Fracture
Status: TERMINATED
Conditions: Femoral Fracture
Interventions: OTHER: Goal directed haemodynamic treatment|OTHER: Routine fluid treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Performance of a Bausch & Lomb Multipurpose Solution and Alcon OptiFree Replenish Multipurpose Solution
Status: COMPLETED
Conditions: Adverse Effect of Contact Lens Solution
Interventions: DEVICE: Bausch & Lomb Multipurpose Solution|DEVICE: Alcon OptiFree Replenish Multipurpose Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Evaluate Recombinant Human Follicle Stimulating Hormone-CTP Fusion Protein Injection or Placebo Combined With Chorionic Gonadotropin for Injection
Status: NOT_YET_RECRUITING
Conditions: Idiopathic Hypogonadotropic Hypogonadism
Interventions: DRUG: recombinant human follicle-stimulating hormone-CTP Fusion protein injection|DRUG: recombinant human follicle-stimulating hormone-CTP Fusion protein injection Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Effect of TC-6499 on Gastric Emptying Time in Diabetic Subjects With Gastroparesis
Status: COMPLETED
Conditions: Gastroparesis
Interventions: DRUG: TC-6499|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Empagliflozin and Dulaglutide on MAFLD in Patients With T2D
Status: NOT_YET_RECRUITING
Conditions: Metabolic-associated Fatty Liver Disease|Type 2 Diabetes
Interventions: DRUG: Empagliflozin|DRUG: Dulaglutide|DRUG: Empagliflozin and Dulaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Mamma Mia" for Perinatal Health and Wellness
Status: ACTIVE_NOT_RECRUITING
Conditions: Perinatal Depression
Interventions: DEVICE: Mamma Mia|OTHER: Mamma Mia Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pembrolizumab and Palliative Radiation Therapy in Treating Patients With Metastatic Esophagus, Stomach, or Gastroesophageal Junction Cancer
Status: COMPLETED
Conditions: Gastric Adenocarcinoma|Gastric Squamous Cell Carcinoma|Gastroesophageal Junction Adenocarcinoma|Metastatic Malignant Neoplasm in the Stomach|Stage IV Esophageal Adenocarcinoma AJCC v7|Stage IV Esophageal Squamous Cell Carcinoma AJCC v7
Interventions: RADIATION: External Beam Radiation Therapy|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Desmopressin Response in the Young
Status: COMPLETED
Conditions: Primary Nocturnal Enuresis
Interventions: DRUG: desmopressin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metered Cryospray for the Treatment of Patients With Chronic Obstructive Pulmonary Disease With Chronic Bronchitis
Status: ACTIVE_NOT_RECRUITING
Conditions: COPD|Chronic Bronchitis
Interventions: DEVICE: RejuvenAir System|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Prophylaxis for Elective Cesarean Section
Status: COMPLETED
Conditions: Infection of Cesarian Section Wound Following Delivery
Interventions: DRUG: ceftriaxone 1gm for intravenous infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: McKenzie Exercises for Chronic Neck Pain: Stabilization vs. Non-Stabilization
Status: COMPLETED
Conditions: Neck Pain|Cervical Pain
Interventions: OTHER: Mckenzie exercise for neck|OTHER: Stabilization exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer
Status: RECRUITING
Conditions: Clinical Stage IV Gastric Cancer AJCC v8|Clinical Stage IVA Gastric Cancer AJCC v8|Clinical Stage IVB Gastric Cancer AJCC v8|Malignant Uterine Neoplasm|Metastatic Appendix Carcinoma|Metastatic Colorectal Carcinoma|Metastatic Gastric Carcinoma|Metastatic Malignant Neoplasm in the Peritoneum|Metastatic Malignant Solid Neoplasm|Metastatic Ovarian Carcinoma|Pathologic Stage IV Gastric Cancer AJCC v8|Peritoneal Carcinomatosis|Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8|Stage IV Appendix Carcinoma AJCC v8|Stage IV Colorectal Cancer AJCC v8|Stage IV Ovarian Cancer AJCC v8|Stage IV Uterine Corpus Cancer AJCC v8|Stage IVA Appendix Carcinoma AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVA Ovarian Cancer AJCC v8|Stage IVA Uterine Corpus Cancer AJCC v8|Stage IVB Appendix Carcinoma AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVB Ovarian Cancer AJCC v8|Stage IVB Uterine Corpus Cancer AJCC v8|Stage IVC Appendix Carcinoma AJCC v8|Stage IVC Colorectal Cancer AJCC v8
Interventions: PROCEDURE: Biopsy|DRUG: Cisplatin|DRUG: Doxorubicin|DRUG: Fluorouracil|DEVICE: Intraperitoneal Chemotherapy|DRUG: Irinotecan|DRUG: Leucovorin|DRUG: Mitomycin|DRUG: Oxaliplatin|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PA21 Phase II Clinical Study in Hemodialysis Patients With Hyperphosphatemia
Status: COMPLETED
Conditions: Chronic Kidney Disease Requiring Hemodialysis
Interventions: DRUG: PA21|DRUG: PA21|DRUG: PA21|DRUG: PA21|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Management of Palmar-plantar Erythrodysesthesia (PPE) in Patients With Metastatic Ovarian or Breast Cancer Treated With Caelyx (Study P05020)
Status: COMPLETED
Conditions: Ovarian Neoplasms|Breast Neoplasms|Paresthesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Yogurt With Probiotics in Adults With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Lactobacillus acidophilus 207, Bifidobacterium lactis B420/205|DIETARY_SUPPLEMENT: Lactobacillus bulgaricus and Streptococcus thermophillus|DIETARY_SUPPLEMENT: No culture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Effectiveness of a New Pleural Catheter for Symptomatic, Recurrent, MPEs Versus Approved Pleural Catheter
Status: COMPLETED
Conditions: Malignant Pleural Effusion
Interventions: DEVICE: Active Comparator: Approved Uncoated PleurX Indwelling Pleural Catheter|DEVICE: Experimental: Silver Nitrate Coated Indwelling Pleural Catheter (SNCIPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Metabolomic Study of All-age Cardiomyopathy
Status: UNKNOWN
Conditions: Dilated Cardiomyopathy|Hypertrophic Cardiomyopathy|Arrhythmogenic Right Ventricular Cardiomyopathy|Left Ventricular Non-compaction|Restrictive Cardiomyopathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Human Albumin for the Treatment of Ascites in Patients With Hepatic Cirrhosis
Status: COMPLETED
Conditions: Liver Cirrhosis|Ascites
Interventions: DRUG: Diuretics plus human albumin|DRUG: Diuretics (standard medical treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Mechanisms of Antipsychotic-induced Insulin Resistance
Status: COMPLETED
Conditions: Adverse Effect of Other Antipsychotics and Neuroleptics|Insulin Resistance
Interventions: DRUG: olanzapine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Lutein Supplementation on Oxidative Stress and Inflammation in Healthy Nonsmokers
Status: UNKNOWN
Conditions: Oxidative Stress in Healthy Subjects
Interventions: DRUG: Lutein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Melatonin in Lumbar Laminectomy
Status: UNKNOWN
Conditions: Pain and Anxiety in Patients Undergoing Surgery for Lumbar Laminectomy.
Interventions: DIETARY_SUPPLEMENT: 5 mg melatonin|DIETARY_SUPPLEMENT: 10 mg melatonin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT