pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Combination Chemotherapy in Treating Children With Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: sargramostim|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Jaktinib for the Treatment of Ruxolitinib Intolerance of Myelofibrosis
Status: COMPLETED
Conditions: Primary Myelofibrosis (PMF)|Post-polycythemia Vera Myelofibrosis(Post-PV MF)|Post-essential Thrombocythemia Myelofibrosis(Post-ET MF)
Interventions: DRUG: Jaktinib hydrochloride tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Kinesiology Tape Wrapping for Paronychia Induced by Epidermal Growth Factor Receptor Inhibitors
Status: COMPLETED
Conditions: Paronychia|Epidermal Growth Factor Receptor Inhibitor
Interventions: COMBINATION_PRODUCT: Kinesiology tape wrapping|DRUG: Conventional treatment including silver nitrate cauterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of the Treatment of Central Serous Chorioretinopathy With Ketoconazole
Status: COMPLETED
Conditions: Chronic Central Serous Chorioretinopathy
Interventions: DRUG: ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label, Phase II Study of Stomatitis Prevention With a Steroid-based Mouthwash in Post-menopausal Women With Estrogen-receptor-positive (ER+), Human Epidermal Growth Factor Receptor 2 (HER2)- Metastatic or Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Advanced Breast Cancer
Interventions: DRUG: Dexamethasone based mouthwash|DRUG: Everolimus|DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects on the Airway Lumen of Talsaclidine in Combination With Propranolol in Comparison to the Effects of the Monosubstances in Healthy Elderly Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Propranolol|DRUG: Talsaclidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcatheter Arterial Chemoembolization With KMG Microsphere Treating Advance-stage Hepatocellular Carinomas
Status: UNKNOWN
Conditions: Carcinoma, Hepatocellular
Interventions: PROCEDURE: Therapeutic Chemoembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PROPOSE Quality - PReOtact in Postmenopausal OStEoporosis - Quality of Life Study (FP-004-DE)
Status: COMPLETED
Conditions: Postmenopause|Osteoporosis
Interventions: DRUG: Parathyroid hormone (PTH) (Preotact)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Primary vs. Secondary Anastomosis for Hinchey Stage III-IV Diverticulitis a Prospective Randomized Trial
Status: COMPLETED
Conditions: Peritonitis
Interventions: PROCEDURE: Hartmann intervention|PROCEDURE: Protected anastomosis resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Absorption, Metabolism, and Excretion (AME) Study of [14C]EDP-938 in Healthy Male Subjects
Status: COMPLETED
Conditions: Respiratory Syncytial Virus (RSV)
Interventions: DRUG: EDP-938
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lymphocyte Depletion and Change in Lymphocyte Functionality
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphocyte Depletion
Interventions: RADIATION: SBRT with additional treatment planning dose optimization|RADIATION: SBRT with standard of care planning only|DIAGNOSTIC_TEST: Blood Draws
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of a Multi-level Clinic and Family Asthma Intervention With a Randomized Control Trial
Status: COMPLETED
Conditions: Infantile Asthma
Interventions: BEHAVIORAL: CALMA plus|BEHAVIORAL: CALMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Aspirin Resistance in Women With Migraine
Status: WITHDRAWN
Conditions: Episodic Migraine|Chronic Migraine
Interventions: DRUG: Aspirin (acetylsalicylic acid)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Trial of a New Formulation of KRX-0502 (Ferric Citrate) in Patients With End-Stage Renal Disease
Status: COMPLETED
Conditions: Hyperphosphatemia|End-stage Renal Disease|Renal Failure Chronic Requiring Hemodialysis
Interventions: DRUG: ferric citrate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Inclisiran Combined With Statins on the Morphology of Coronary Vulnerable Plaques
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DRUG: Inclisiran sodium|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Monolithic CAD/CAM Single Tooth Ceramic Crowns
Status: COMPLETED
Conditions: Crowns (MeSH Unique ID: D003442), Single Tooth|Dental Porcelain (MeSH Unique ID: D003776)
Interventions: OTHER: Zirconium-reinforced glass ceramics(ZRGC),Lithium disilicate glass ceramics(LGC), Resin infiltrated glass ceramics(RIGC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Preference for Pegfilgrastim (Neulasta®) Application Forms
Status: COMPLETED
Conditions: Non Hodgkin Lymphoma|Breast Cancer
Interventions: DEVICE: On-body injector|DEVICE: Pre-filled syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ropivacaine Plus Magnesium Sulphate Infiltration
Status: COMPLETED
Conditions: Thyroid Diseases|Parathyroid Diseases|Postoperative Pain|Anesthesia, Local
Interventions: DRUG: Placebo Comparator: N/S 0.9%|DRUG: Ropivacaine 10%|DRUG: Ropivacaine 10% plus magnesium sulphate 10mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Antibiotic or Not in Non-purulent Exacerbations of COPD: a Trial of Security and Efficacy
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Formulation for Angelman Syndrome
Status: COMPLETED
Conditions: Angelman Syndrome
Interventions: DIETARY_SUPPLEMENT: Nutritional Formulation Containing Exogenous Ketones|DIETARY_SUPPLEMENT: Placebo Formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Trial of Carfilzomib, Lenalidomide, Dexamethasone Versus Lenalidomide Alone After Stem-cell Transplant for Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: Carfilzomib|DRUG: Dexamethasone|DRUG: Lenalidomide (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cocaine/Crack and Reduction of Compulsion With Biperiden
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: Biperiden|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bromelin, a Compound Prepared With Ananas Comocus Extract and Honey, for Acute Cough
Status: UNKNOWN
Conditions: Cough, Acute
Interventions: DRUG: Bromelin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Ex-vivo Evaluation of the Reactivity of the Immune Infiltrate of Cancers to Treatments With Monoclonal Antibodies Targeting the Immunomodulatory Pathways
Status: UNKNOWN
Conditions: Cancer
Interventions: PROCEDURE: Tissue sampling|PROCEDURE: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Repeated Treatments of QLT091001 in Subjects With Leber Congenital Amaurosis or Retinitis Pigmentosa (Extension of Study RET IRD 01)
Status: COMPLETED
Conditions: LCA (Leber Congenital Amaurosis)|RP (Retinitis Pigmentosa)
Interventions: DRUG: QLT091001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Persistence and Booster Study of GSK Biologicals' Meningococcal Vaccine (GSK134612) in Healthy Children
Status: COMPLETED
Conditions: Infections, Meningococcal|Meningococcal Vaccines
Interventions: BIOLOGICAL: Nimenrix (GSK134612 vaccine)|BIOLOGICAL: Menjugate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Oral Etrasimod Versus Placebo for the Treatment of Moderately to Severely Active Ulcerative Colitis in Adult Japanese Participants (ELEVATE UC 40 JAPAN)
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Etrasimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenetic and Pharmacokinetics of Naproxen and Associated Naproxen-esomeprazole
Status: COMPLETED
Conditions: Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant|Poor Metabolizer Due to Cytochrome p450 CYP2C19 Variant
Interventions: DRUG: Naproxen|DRUG: Naproxen-esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of a Probiotic Strain on Level of Markers of Inflammation in an Elderly Population
Status: COMPLETED
Conditions: Inflammation
Interventions: DIETARY_SUPPLEMENT: Experimental: Bif-038 arm, high dose|DIETARY_SUPPLEMENT: Experimental: Bif-038 arm, low dose|DIETARY_SUPPLEMENT: Placebo Comparator: Placebo arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Response of Continuous Recombinant Antithrombin Infusion in Postcardiotomy ECMO Patients
Status: WITHDRAWN
Conditions: Antithrombin Deficiency Type 2
Interventions: DRUG: ATryn continuous infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ultrasound Guided Blocks of the Iliohypogastric and Ilioinguinal Nerves in Persistent Postherniorrhaphy Pain Patients
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: lidocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Comparing Mini-Incision Versus 2-Incision Approach for Total Hip Replacement
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Mini Incision Approach|PROCEDURE: 2 Incision Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Combination Chemotherapy With or Without Surgery & Chemoradiotherapy in Patients With Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Malignant Mesothelioma
Interventions: DRUG: Cisplatin|DRUG: Methotrexate|DRUG: Vinorelbine ditartrate|PROCEDURE: Adjuvant therapy|PROCEDURE: Conventional surgery|PROCEDURE: Neoadjuvant Therapy|RADIATION: 3-dimensional conformal radiation therapy|RADIATION: Intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Imaging of Core Muscles Activity in Multiparous Women With Vaginal Laxity: A Cross-Sectional Study
Status: COMPLETED
Conditions: Vaginal Laxity
Interventions: OTHER: Evaluating sexual function, quality of life and pelvic floor muscle strength, as well as thickness and force (strength) of voluntary contractions of the core muscles
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Single Dose Of Compound SB-681323 Compared To Prednisolone On A Protein That Is an Indicator For Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Prednisolone|DRUG: SB-681323
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MYREPTIC-N® or MY-REPT® in Stable Patients After Kidney Transplant Recipients
Status: RECRUITING
Conditions: Kidney Transplant
Interventions: DRUG: Myreptic-N Tablet|DRUG: Mycophenolate mofetil Tablet/Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation in Laryngeal Dystonia and Voice Tremor
Status: RECRUITING
Conditions: Laryngeal Dystonia|Spasmodic Dysphonia|Tremor|Dystonia
Interventions: PROCEDURE: Deep Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Non-Interventional Study on the Tolerability and Efficacy of IVIG
Status: COMPLETED
Conditions: Primary and Secondary Immunodeficiency and Other Conditions Requiring Regular Administration of Octagam 5% or 10% IVIG
Interventions: BIOLOGICAL: Octagam IVIG 5% or 10%|BIOLOGICAL: Panzyga
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: hsCRP & CH Indices in Patients With Coronary Artery Disease With and Without Apical Periodontitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Apical Periodontitis|Coronary Artery Disease
Interventions: PROCEDURE: Endodontic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Integrative Cardiac Rehabilitation Employing Smartphone Technology (iCREST)
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: BEHAVIORAL: Traditional Centre-based Cardiac Rehabilitation (CBCR) group|BEHAVIORAL: I-CREST group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Commerical DHA Supplementation
Status: TERMINATED
Conditions: Randomized Clinical Trial|Docosahexaenoic Acid|Pregnancy
Interventions: DIETARY_SUPPLEMENT: Expecta 200mg DHA|DIETARY_SUPPLEMENT: Promise 275mg DHA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Open-label Prospective Cohort Trial of Curcumin Plus Tyrosine Kinase Inhibitors (TKI) for EGFR -Mutant Advanced NSCLC
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DIETARY_SUPPLEMENT: CurcuVIVA™|DRUG: Tyrosine Kinase Inhibitor gefitinib (Iressa)|DRUG: Tyrosine Kinase Inhibitor erlotinib (Tarceva)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A MAajor RAdiation-based PCI Study in STEMI and NSTEMI
Status: NOT_YET_RECRUITING
Conditions: Myocardial Infarction (MI)|Radiation Toxicity|Coronary Stenosis|Coronary Thrombosis|Coronary Artery Calcification|Coronary Occlusion|Coronary Syndrome|Coronary Artery Disease
Interventions: DEVICE: Non Complex PCI|DEVICE: Complex PCI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study to Evaluate the Efficacy of TQA3038 Injection in Patients With Chronic Hepatitis B
Status: NOT_YET_RECRUITING
Conditions: Hepatitis B, Chronic
Interventions: DRUG: TQA3038 injection/placebo|DRUG: Nucleotide drugs Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Feasibility of Dexmedetomidine for Awake Fiberoptic Nasal Intubation
Status: UNKNOWN
Conditions: Awake Fiberoptic Nasal Intubation
Interventions: DRUG: dexmedetomidine|DRUG: Normal Saline 0.9%|DRUG: propofol 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Biofeedback in the Treatment of Tic Disorder
Status: SUSPENDED
Conditions: Tic Disorders
Interventions: DRUG: Drug Aripiprazole|DEVICE: biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dumping Syndrome and Esophageal Atresia
Status: UNKNOWN
Conditions: Oesophageal Atresia|Dumping Syndrome
Interventions: DEVICE: Glycemic Holter|RADIATION: gastric emptying scintigraphy|DEVICE: Holter ECG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Empowering Young Parents: Building Healthy Relationships Study
Status: NOT_YET_RECRUITING
Conditions: Gender-based Violence|Intimate Partner Violence
Interventions: BEHAVIORAL: Safe Dates for Young Parents (SDYP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: TAIZ -Monocytes for the Induction of Donor Specific Tolerance in Renal Allograft Recipients (Cadaver Kidney)
Status: UNKNOWN
Conditions: Renal Transplantation
Interventions: DRUG: TAIZ
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Study of 18F-mFBG for Imaging Myocardial Sympathetic Innervation
Status: RECRUITING
Conditions: Cardiovascular Diseases
Interventions: DRUG: 18F-mFBG for intravenous administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mindful Movement for Physical Activity and Wellbeing in Older Adults- A Hybrid Effectiveness-Implementation Study
Status: COMPLETED
Conditions: Physical Inactivty|Wellbeing|Mindfulness
Interventions: BEHAVIORAL: Mindful Movement|OTHER: Keys to Health & Wellbeing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Multi-Center, Double-Masked, Randomized, Vehicle-Controlled, Parallel-Group Clinical Trial Evaluating the Safety of Reproxalap Ophthalmic Solution in Subjects With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: Reproxalap Ophthalmic Solution (0.25%)|DRUG: Placebo Comparator|DRUG: Reproxalap Ophthalmic Solution (0.25%)|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Markers of Neuroplasticity During Exercise in People With Incomplete Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DRUG: escitalopram oxalate|DRUG: Cyproheptadine|DRUG: sugar pill|OTHER: Graded intensity exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Insulin Resistance in Multiple System Atrophy
Status: UNKNOWN
Conditions: Multiple System Atrophy
Interventions: BIOLOGICAL: Homeostasis Model Assessment of insulin resistance (HOMA)|BEHAVIORAL: MOntreal Cognitive Assessment (MoCA)|BEHAVIORAL: Clinical characteristics of AMS patients|PROCEDURE: Brain Magnetic Resonance Imaging (MRI)|BIOLOGICAL: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase I, Open-label, Study of Pazopanib in Combination With Epirubicin or Doxorubicin for Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: Doxorubicin|DRUG: Pazopanib (GW786034)|DRUG: Epirubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Quality of Life and Tolerance of Patients Treated With Vectorized Internal Radiotherapy (RIV) for a Neuro Endocrine Tumor (NET) in the Auvergne-Rhône-Alpes Region.
Status: RECRUITING
Conditions: Metastatic Neuroendocrine Tumour
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PEG3350 in ACLF With Hepatic Encephalopathy
Status: UNKNOWN
Conditions: Hepatic Encephalopathy|Acute-On-Chronic Liver Failure
Interventions: DRUG: PEG-3350 with Electolytes|DRUG: Lactulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Natural Orifice Translumenal Endoscopic Surgery (NOTES) Cystgastrostomy for the Treatment of Pancreatic Pseudocysts
Status: TERMINATED
Conditions: Pancreatic Pseudocyst
Interventions: PROCEDURE: Pancreatic Pseudocystgastrostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of a Modified Cystoscopy Method to Reduce Pain Perception
Status: COMPLETED
Conditions: Hematuria|Bladder Cancer|Bladder Disease
Interventions: BEHAVIORAL: Modified Cystoscopy|BEHAVIORAL: Routine Cystoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Safety and Performance of Ialuxid Gel in Treatment of Acne Vulgaris, and Folliculitis
Status: COMPLETED
Conditions: Acne Vulgaris|Folliculitis
Interventions: DEVICE: Ialuxid gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerability and Acceptability of Fibersol-2 in Children
Status: COMPLETED
Conditions: Diarrhea
Interventions: COMBINATION_PRODUCT: Fibersol-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CD19 Targeted CAR T Cell Therapy in Patients With Relapsed/ Refractory B Cell Acute Lymphoblastic Leukaemia (ALL)
Status: UNKNOWN
Conditions: Relapsed B Cell Acute Lymphoblastic Leukemia (ALL)|Refractory B Cell Acute Lymphoblastic Leukemia (ALL)
Interventions: BIOLOGICAL: CD19 CAR engineered autologous T-cells|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Mesna
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RELAX: Reducing Length of Antibiotics for Children With Ear Infections
Status: NOT_YET_RECRUITING
Conditions: Acute Otitis Media|Pediatric Infectious Disease|Ear Infection
Interventions: OTHER: High Intensity Intervention|OTHER: Low Intensity Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ticagrelore Alone Post PCI
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DRUG: aspirin 80 mg and clopidogrel 75 mg daily|DRUG: Ticagrelor 90 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Grape Seed Extract on Blood Pressure
Status: COMPLETED
Conditions: Elevated Blood Pressure
Interventions: DIETARY_SUPPLEMENT: Grape seed extract|DIETARY_SUPPLEMENT: Microcrystalline cellulose (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study In Healthy Volunteers To Assess The Safety, Tolerability, And Relative Oral Bioavailability Of Three Formulations Of PH-797804
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PH-797804 material sparing tablet|DRUG: PH-797804 Phase2b/3 with sodium lauryl sulphate|DRUG: PH-797804 Phase2b/3 with sodium lauryl sulphate|DRUG: PH-797804 material sparing tablet|DRUG: PH-797804 material sparing tablet|DRUG: PH-797804 Phase2b/3 without sodium lauryl sulphate|DRUG: PH-797804 Phase2b/3 without sodium lauryl sulphate|DRUG: PH-797804 material sparing tablet|DRUG: PH-797804 Phase2b/3 without sodium lauryl sulphate|DRUG: PH-797804 Phase2b/3 with sodium lauryl sulphate|DRUG: PH-797804 Phase2b/3 with sodium lauryl sulphate|DRUG: PH-797804 Phase2b/3 without sodium lauryl sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose Range Study of Anamorelin in Patients With Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: anamorelin HCl|DRUG: anamorelin HCl|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peritoneal Ropivacaine Infiltration on Postoperative Pain in Children Affected
Status: COMPLETED
Conditions: Testicular|Colic
Interventions: DRUG: intraperitoneal infiltration of ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Daily Average Requirement of Iodine in Lactating Women
Status: UNKNOWN
Conditions: Healthy|Iodine Deficiency
Interventions: DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: Iodide (150 μg/day)|DIETARY_SUPPLEMENT: Iodine (300 μg/day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized Phase III Clinical Trial of Daunoxome Versus Combination Chemotherapy With Adriamycin/Bleomycin/Vincristine (ABV) in the Treatment of HIV-Associated Kaposi's Sarcoma.
Status: COMPLETED
Conditions: Sarcoma, Kaposi|HIV Infections
Interventions: DRUG: Daunorubicin (liposomal)|DRUG: Bleomycin sulfate|DRUG: Vincristine sulfate|DRUG: Doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Methylene Blue and Microcirculation in Septic Shock
Status: UNKNOWN
Conditions: Septic Shock
Interventions: DRUG: Methylene Blue|DRUG: Norepinephrine infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Follow-up After Hiatal Hernia Repair by Tension-free Mesh Closure or Simple Suturing
Status: COMPLETED
Conditions: GERD|Hiatal Hernia|Dysphagia, Esophageal|Quality of Life
Interventions: PROCEDURE: simple suturing|PROCEDURE: mesh
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot Study Assessing Impulsivity in Patients With Huntington's Disease on Xenazine (Tetrabenazine)
Status: UNKNOWN
Conditions: Huntington's Disease
Interventions: DRUG: Tetrabenazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of Gefitinib in Adjuvant Chemotherapy for Lung Adenocarcinoma
Status: UNKNOWN
Conditions: NSCLC|EGFR
Interventions: DRUG: Gefitinib|DRUG: Vinorelbine|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Meningococcal Groups A and C and Haemophilus b Conjugate Vaccine in Infants 2 to 5 Months of Age
Status: UNKNOWN
Conditions: Meningitis|Meningococcal Meningitis|Meningococcal Infections
Interventions: BIOLOGICAL: Meningococcal Groups A and C and Haemophilus b Conjugate Vaccine (adjuvant-free)|BIOLOGICAL: Meningococcal Groups A and C and Haemophilus b Conjugate Vaccine(adjuvant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Find a Suitable Dose of BI 765883 and to Test Whether it Helps People With Advanced Pancreatic Cancer When Taken Alone or Together With Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: BI 765883|DRUG: gemcitabine|DRUG: nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Diet and Physical Activity on Incidence of Type 2 Diabetes
Status: COMPLETED
Conditions: Pre-diabetes|Obesity
Interventions: BEHAVIORAL: High protein/ high intensity physical activity (HP-HI)|BEHAVIORAL: High protein / moderate intensity physical activity (HP-MI)|BEHAVIORAL: Moderate protein/ high intensity physical activity (MP-HI)|BEHAVIORAL: Moderate protein/ moderate intensity physical activity (MP-MI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Travoprost Five Day Posology Study
Status: COMPLETED
Conditions: Open-angle Glaucoma (OAG)|Ocular Hypertension
Interventions: DRUG: Travoprost 0.004%|DRUG: Travoprost Vehicle|DRUG: Travoprost (Groups A, B and C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine if Taking OTC Non-Steroidal Anti-Inflammatory Affects Eye Pressure in Patients Using Glaucoma Drops
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: ibuprofen, latanoprost, brimonidine|DRUG: Ibuprofen, brimonidine, latanoprost|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FLOT Combined With PD-1 in the First-line Treatment of Patients With Advanced Gastric Cancer and Peritoneal Metastasis
Status: UNKNOWN
Conditions: Chemotherapy|Gastric Cancer
Interventions: DRUG: FLOT(Docetaxel+oxaliplatin+leucovorin+5-FU), Treprizumab, Tiggio capsule (S-1)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Chinese Herbal Compound TJAOA101 in Therapy of Diminished Ovarian Reserve
Status: NOT_YET_RECRUITING
Conditions: Diminished Ovarian Reserve
Interventions: DRUG: TJAOA101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endostar Continued Pumping Into Vein Combining With Gemcitabine-Carboplatin to Treat Non-Small Cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Gemcitabine,Carboplatin,Endostar|DRUG: Gemcitabine(G) Carboplatin(C) Endostar|DRUG: Gemcitabine(G) Carboplatin(C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-field MR Imaging in Migraine and Epilepsy
Status: NOT_YET_RECRUITING
Conditions: Migraine|Epilepsy
Interventions: DIAGNOSTIC_TEST: Structural MRI|DIAGNOSTIC_TEST: Quantitative MRI|DIAGNOSTIC_TEST: Diffusion MRI|DIAGNOSTIC_TEST: fMRI|DIAGNOSTIC_TEST: MR Spectroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Temsirolimus in Treating Patients With Refractory or Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Primary Peritoneal Cavity Cancer|Recurrent Ovarian Epithelial Cancer
Interventions: DRUG: temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketoprofen Lysine Salt as Mouthwash in Acute Phlogosis of the Pharyngeal Cavity Versus Benzidamine Hydrochloride
Status: COMPLETED
Conditions: Pharyngitis
Interventions: DRUG: Benzidamine hydrochloride|DRUG: Ketoprofen lysine salt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Trial Evaluating the Efficacy of a Chlorhexidine-Impregnated Sponge (BIOPATCH®) to Reduce Catheter-Related Bloodstream Infections in Hemodialysis Patients
Status: COMPLETED
Conditions: Catheter Related Bloodstream Infection
Interventions: DEVICE: Chlorhexidine-impregnated foam dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Kedrion IVIG 10% to Treat Subjects With Primary Immunodeficiency (PID)
Status: COMPLETED
Conditions: Primary Immunodeficiency|Agammaglobulinemia|Hypogammaglobulinemia|Antibody Deficiency
Interventions: BIOLOGICAL: Kedrion IVIG 10%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered Malignancies
Status: AVAILABLE
Conditions: Pancreatic Cancer|Small Bowel Cancer|Colorectal Cancer|Melanoma|Non Small Cell Lung Cancer|Thyroid Cancer|Bladder Cancer|Head and Neck Cancer|Gastric Cancer|Esophageal Cancer|Cholangiocarcinoma|Ovarian Cancer|Hepatocellular Carcinoma|Glioblastoma|MAPK Gene Mutation|KRAS Activating Mutation|BRAF Gene Mutation|NRAS Gene Mutation|HRAS Gene Mutation|MEK Mutation|ERK Mutation
Interventions: DRUG: Ulixertinib (BVD-523)
Study Type: EXPANDED_ACCESS
Clinical trial: Induced-T Cell Like NK Cells for B Cell Malignancies
Status: UNKNOWN
Conditions: B Cell Leukemia|B Cell Lymphoma|B-cell Acute Lymphoblastic Leukemia|B-cell Lymphoma Recurrent|B-cell Lymphoma Refractory
Interventions: BIOLOGICAL: CAR-ITNK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing the PathKeeper System for Pedicle Screw Positioning in Spine Surgery With Traditional Care
Status: NOT_YET_RECRUITING
Conditions: Scoliosis|Scoliosis; Adolescence|Scoliosis Kyphosis|Scoliosis Lumbar Region|Scoliosis Thoracic Region|Pathologic Fracture
Interventions: DEVICE: Medical Device - PKS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Osteopathic Manual Techniques on the Diaphragm Muscle and Its Repercussions
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: OTHER: Intervention Protocol in Diaphragm|OTHER: Sham technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy Study of Early Versus Late Oseltamivir Administration for Treating and Preventing Influenza
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: Oseltamivir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Antibiotics in Cerebrospinal Fluid Following Intravenous Injection
Status: WITHDRAWN
Conditions: Neurosurgery
Interventions: DRUG: Vancomycin|DRUG: Teicoplanin|DRUG: Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Online Remote Behavioural Intervention for Tics (ORBIT)
Status: COMPLETED
Conditions: Tic Disorders|Tourette Syndrome
Interventions: BEHAVIORAL: Exposure Response Prevention for tics|OTHER: Psychoeducation for tics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cervical I/F Cage for Anterior Cervical Fusion
Status: COMPLETED
Conditions: Cervical Intervertebral Disc Degeneration
Interventions: DEVICE: Cervical I/F Cage|DEVICE: Autograft or allograft with a plate, or autograft alone.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study Evaluating a Combination of Oregovomab and Niraparib in Adult Women With Platinum Sensitive Recurrent Ovarian Cancer.
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Ovarian Cancer|Recurrent Epithelial Cancer of Ovary|Recurrent Epithelial Ovarian Cancer|Recurrent Fallopian Tube Cancer|Peritoneal Cancer|Recurrent Carcinoma of Ovary|Adenocarcinoma of Ovary
Interventions: BIOLOGICAL: Oregovomab|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Russian Prospective Multicenter Registry Study of Intravenous Thrombolytic Therapy for Acute Ischemic Stroke
Status: UNKNOWN
Conditions: The Aim the Study is to Collect and Analyze Data on Patients With Acute Ischemic Stroke During Intravenous Thrombolytic Therapy With Alteplase
Interventions: DRUG: Revelisa
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gingival Recession (RT1) Treatment With Different Gingival Augmentation Surgeries
Status: RECRUITING
Conditions: Gingival Recession
Interventions: PROCEDURE: Connective tissue graft|PROCEDURE: Free gingival graft|PROCEDURE: Non surgical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accessory Joint and Neural Mobilizations in Shoulder After Breast Cancer Surgery. Randomized Clinical Trial.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: Accessory joint mobilization|OTHER: Nerve mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Upadacitinib in Adolescent and Adult Patients With Moderate to Severe Atopic Dermatitis (Eczema)
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: Placebo for Upadacitinib|DRUG: Upadacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Chemotherapy Plus Radiation Therapy in Treating Women With Early-Stage Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: CMF regimen|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: epirubicin hydrochloride|DRUG: fluorouracil|DRUG: methotrexate|DRUG: mitomycin C|DRUG: mitoxantrone hydrochloride|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Delayed Loading Following Repair of a Ruptured Achilles Tendon
Status: COMPLETED
Conditions: Achilles Tendon Rupture
Interventions: OTHER: Rehabilitation (physiotheraphy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Lactobacillus Coryniformis CECT5711 on Immune Response to Influenza Vaccination in Adults Over 65.
Status: COMPLETED
Conditions: Influenza Vaccination|Immune Response|Probiotics
Interventions: DIETARY_SUPPLEMENT: Lactobacillus coryniformis K8 CECT5711|OTHER: Control placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Understanding the Effect of Metformin on Corus CAD (or ASGES)
Status: COMPLETED
Conditions: Coronary Artery Disease|Angina Pectoris|Chest Pain|Cardiovascular Diseases|Coronary Heart Disease|CAD|CVD|CHD
Interventions: DIAGNOSTIC_TEST: Corus CAD (ASGES)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Involvement of Fatty Acids in Retinopathy of Prematurity: Relationship Between Retinopathy of Prematurity and the Rate of Expression of Transplacental Fatty Acid Receptors.
Status: RECRUITING
Conditions: Prematurity|Retinopathy
Interventions: BIOLOGICAL: Maternal blood sampling|BIOLOGICAL: Umbilical cord blood sampling|BIOLOGICAL: Placenta sampling|OTHER: Data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The TriggerHappy Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Trigger Finger|Trigger Thumb|Minimally Invasive Surgery
Interventions: PROCEDURE: Proximal phalangeal level|DRUG: Volar to the MCP-joint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-based Mobile Health Application for Patients With Liver Cirrhosis (ReLiver-N App)
Status: RECRUITING
Conditions: Mobile Health|Liver Cirrhosis|Patient Activation
Interventions: BEHAVIORAL: ReLiver-N App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose-Ranging Study for Prolonged Postoperative Analgesia in Subject Undergoing Total Knee Arthroplasty
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Bupivacaine HCl|DRUG: SKY0402
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Clinical Study to Evaluate the Long-term Efficacy and Safety of Repeat Treatment of YVOIRE Contour Injected Into the Anteromedial Malar Region in Subjects Who Have Completed the LG-HACL014 Study
Status: COMPLETED
Conditions: Normal, Healthy Adults With Moderate, Severe, or Very Severe Volume Loss of Anteromedial Malar Region Who Have Completed the LG-HACL014 Study
Interventions: DEVICE: YVOIRE contour
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LN-144 in People With Metastatic Melanoma to the Brain
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Melanoma
Interventions: BIOLOGICAL: Lifileucel (LN-144)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cartography of Social Cognition Network and Their Alterations in Patients With Epilepsy
Status: NOT_YET_RECRUITING
Conditions: Epilepsy|Drug Resistant Epilepsy
Interventions: RADIATION: MRI 3T and MRI 7T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of the Safety, Tolerability, and Effects of Cobimetinib and GDC-0994 in Patients With Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer, Metastatic Colorectal Cancer, Metastatic Non Small Cell Lung Cancer, Metastatic Cancers, Melanoma
Interventions: DRUG: Cobimetinib|DRUG: GDC-0994
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Dexlansoprazole MR and Lansoprazole on Healing of Erosive Esophagitis
Status: COMPLETED
Conditions: Esophagitis, Reflux|Esophagitis, Peptic
Interventions: DRUG: Dexlansoprazole MR|DRUG: Dexlansoprazole MR|DRUG: Lansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cutaneous Sensory Block Area of the Subcostal Ultrasound-Guided Transversus Abdominis Plane Block
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Ultrasound-guided subcostal transversus abdominis plane block (US-TAP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Incidence of Chemotherapy-Induced Nausea and Vomiting Associated With Docetaxel-Cyclophosphamide in Early Breast Cancer.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Aprepitant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification of C7; Evaluations of 2 Sonographic Methods Using a Transverse and a Sagittal Scan.
Status: COMPLETED
Conditions: Breastcancer
Interventions: DEVICE: Ultrasound sagittal scan|DEVICE: Ultrasound transverse scan|PROCEDURE: Fluoroscopic technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Using Electronic Health Information to Learn About Rivaroxaban Compared to Warfarin in Participants With Non-valvular Atrial Fibrillation (NVAF) and Diabetes
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Warfarin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p