pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: GW572016 With Docetaxel and Trastuzumab for the Treatment Of Untreated ErbB2 Over-Expressing Metastatic Breast Cancer
Status: TERMINATED
Conditions: Neoplasms, Breast
Interventions: DRUG: lapatinib, docetaxel, trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ALS-008176 in Healthy Japanese Adult Participants
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: ALS-008176 (250 mg)|DRUG: ALS-008176 (500 mg)|DRUG: ALS-008176 (750 mg)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: The Optimal Treatment Duration for Inspiratory Muscle Strengthening Exercises in Stroke Patients
Status: COMPLETED
Conditions: Stroke, Complication|Respiratory Complication
Interventions: OTHER: inspiratory muscle training|OTHER: sham intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Biphasic Insulin Aspart 50 and 70 in Japanese Healthy Volunteers
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: biphasic insulin aspart 50|DRUG: biphasic insulin aspart 70
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetics Informatics Trial (GIFT) of Warfarin to Prevent DVT
Status: COMPLETED
Conditions: Thromboembolism
Interventions: GENETIC: Pharmacogenetic|DRUG: Target INR 1.8
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Study of Skeletal Muscle Blood Flow in Becker Muscular Dystrophy
Status: TERMINATED
Conditions: Muscular Dystrophy
Interventions: DRUG: Tadalafil 20 MG|OTHER: beetroot juice extract
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized, Double Blind, 2 Way Crossover Study of CSII With, Versus Without, Pretreatment With Human Hyaluronidase
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Sham Injection|DRUG: Recombinant human hyaluronidase PH20|DRUG: Insulin aspart|DRUG: Insulin lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Poor Ovarian Responders Undergoing IVF Using Luteal Ovarian Stimulation Versus Follicular Ovarian Stimulation
Status: COMPLETED
Conditions: Fertilization in Vitro
Interventions: OTHER: luteal ovarian stimulation|OTHER: follicular ovarian stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Botanical Plant Extract on Gut Health, Immunity and Metabolic Disorders in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Low dose response efficacy of plant extracts|DIETARY_SUPPLEMENT: Middle dose response efficacy of plant extracts|DIETARY_SUPPLEMENT: High Dose response efficacy of plant extracts|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dapagliflozin on IAH in T1DM
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Hypoglycemia|Hypoglycemia Unawareness
Interventions: DRUG: Dapagliflozin|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of a Proliferation Saturation Index to Determine Personalized Radiotherapy for HPV + Oropharyngeal Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Oropharyngeal Cancer
Interventions: RADIATION: Radiotherapy fractionation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Intravenous Lipid Emulsions in Home Parenteral Nutrition Patients
Status: COMPLETED
Conditions: Home Parenteral Nutrition
Interventions: DRUG: SMOFlipid20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intensive Aerobic and Resistance Exercise Program (IAREP)
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes Mellitus|Cognitive Impairment|Non-insulin-dependent Diabetes Mellitus|Cognitive Dysfunction
Interventions: OTHER: Intensive Aerobic and Resistance Exercise Program (IAREP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Therapeutic Exercise Compared to Femoral Nerve Mobilisation in Knee Tendinosis
Status: NOT_YET_RECRUITING
Conditions: Chronic Patellar Tendinopathy
Interventions: PROCEDURE: THERAPEUTIC EXERCISE AND MOBILISATION OF THE FEMORAL NERVE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Systemic Transthyretin Amyloidosis: Carpal Tunnel Syndrome in a Portuguese Population
Status: RECRUITING
Conditions: Transthyretin Amyloidosis|Carpal Tunnel Syndrome
Interventions: DIAGNOSTIC_TEST: Synovial biopsy and Cardiac scintigraphy with [99mTc]Tc-DPD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Switching to Aripiprazole on Heart Health in Overweight and Obese Patients With Schizophrenia
Status: COMPLETED
Conditions: Overweight|Hyperlipidemia|Cardiovascular Diseases
Interventions: DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Selective Cerebrovascular Distribution With FDCT in the Angiosuite
Status: COMPLETED
Conditions: Ischemic Stroke|Intracranial Aneurysm|Intracranial Arterial Diseases|Cerebral Hypoxia|Intracranial Vascular Disorder
Interventions: DIAGNOSTIC_TEST: Intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison Between IV Propofol and Propofol/ Fentanyl Anesthesia on Patients Stress Response
Status: UNKNOWN
Conditions: Stress
Interventions: DRUG: Propofol|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: TEC4Home Stroke - Feasibility of Home Telemonitoring Technology in Managing Hypertension Among Stroke/TIA Patients
Status: COMPLETED
Conditions: Hypertension|Stroke|Blood Pressure, High|Systolic Hypertension|Transient Ischemic Attack|Cerebrovascular Accident
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Outcomes Post Kidney Biopsy - Randomized Clinical Evaluation of Efficacy of Desmopressin
Status: RECRUITING
Conditions: Kidney Biopsy
Interventions: DRUG: Desmopressin|DRUG: intravenous infusion NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Potential for Oral Diindolylmethane (DIM) Supplementation to Increase the Production of the BRCA1 Protein in BRCA1 Mutation Carriers
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DIETARY_SUPPLEMENT: Diindolylmethane (DIM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intervention Study of Face Mask and Hand Sanitizer to Reduce Influenza Transmission
Status: COMPLETED
Conditions: Influenza
Interventions: BEHAVIORAL: Ear Loop Procedure Mask|BEHAVIORAL: 62% Ethyl Alcohol Hand Sanitizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Manual Diaphragm Release on Stepping Reaction Time in Chronic Obstructive Pulmonary Disease
Status: RECRUITING
Conditions: Respiratory Disease
Interventions: OTHER: Manual Diaphragm Release Technique|OTHER: Breathing Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prodrome-Based Early Intervention With Antipsychotics vs. Benzodiazepines in First-Episode Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Psychoses
Interventions: DRUG: antipsychotics vs. Lorazepam (Drugs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of Superiority of POSToperative Pharmaceutical Support on Patients' Knowledge of Their IMPlant
Status: UNKNOWN
Conditions: Health Education, Joint Prosthesis, Breast Implants
Interventions: OTHER: New pharmaceutical support (NPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of YM178 in Patients With Symptomatic Overactive Bladder
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: YM178|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Vertebroplasty Associated With Radiotherapy for Spine Metastases (EVAR)
Status: COMPLETED
Conditions: Osseous Spine Metastases
Interventions: PROCEDURE: injection of orthopaedic cement into vertebral bodies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mifamurtide Combined With Post-operative Chemotherapy for Newly Diagnosed High Risk Osteosarcoma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteosarcoma
Interventions: DRUG: Mifamurtide|COMBINATION_PRODUCT: EI or M-API regimen depending on patient age
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identifying Patients With Suspicion of Infection in the ED Who Have Low Disease Severity Using MR-proADM - Pilot Study
Status: COMPLETED
Conditions: Patients Presenting With Suspicion of Infection to the ED
Interventions: OTHER: MR-proADM guided
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Probiotic Supplementation and Exercise Performance in the Heat
Status: RECRUITING
Conditions: Acute Exercise|Probiotics
Interventions: DIETARY_SUPPLEMENT: Probiotic bacteria|OTHER: Placebo Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: EFFECTİVENESS OF PULSED ULTRASOUND TREATMENT ON PATIENTS WITH BELL'S PALSY
Status: COMPLETED
Conditions: Bell Palsy
Interventions: DEVICE: Therapeutic Pulsed Ultrasound|DEVICE: Sham Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CompariSon of Manual Aspiration With Rheolytic Thrombectomy in Patients Undergoing Primary PCI. The SMART-PCI Trial
Status: COMPLETED
Conditions: ST-segment Elevation Myocardial Infarction|Thrombus
Interventions: PROCEDURE: Manual Thrombectomy|PROCEDURE: AngioJet Rheolytic Thrombectomy (RT) System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endovenous Ablation With and Without Polidocanol Endovenous Microfoam Treatment for Patients With Great Saphenous Vein Incompetence and Visible Varicosities
Status: COMPLETED
Conditions: Great Saphenous Vein Incompetence|Visible Varicosities
Interventions: DRUG: endovenous ablation+polidocanol injectable microfoam 0.125%|DRUG: Endovenous ablation+polidocanol injectable microfoam 1.0%|DRUG: Endovenous ablation+polidocanol injectable foam 2.0%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Food Literacy Intervention - is a "Train the Trainer" Approach Feasible and Effective?
Status: NOT_YET_RECRUITING
Conditions: Lifestyle Risk Reduction|Health Behavior|Food Habits
Interventions: BEHAVIORAL: Lay-led FL workshops|BEHAVIORAL: Expert-led workshops
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: DSC-MRI in Measuring rCBV for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma
Status: RECRUITING
Conditions: Gliosarcoma|Recurrent Glioblastoma
Interventions: DIAGNOSTIC_TEST: Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Research Study of Treatment for Winter Depression With Different Colors of Light
Status: COMPLETED
Conditions: Seasonal Affective Disorder
Interventions: DEVICE: Blue Light Box 467 nm|DEVICE: Red Light Box 657 nm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Carboplatin With Either Paclitaxel Poliglumex or Paclitaxel in Treating Women With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|DRUG: paclitaxel poliglumex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pelvic Nodes Ultra-Hypo vs Conventionally Fractionated IMRT With HDR Boost in Prostate Cancer.
Status: RECRUITING
Conditions: Prostate Cancer|Node; Prostate|Radiotherapy Side Effect
Interventions: RADIATION: Report and compare changes in a non-inferiority analysis of the International Prostate Symptom Score (I-PSS)|RADIATION: Report and compare changes in a non-inferiority analysis of the expanded prostate cancer index composite" (EPIC-26):|RADIATION: Report and compare changes in a non-inferiority analysis of the Sexual Health Inventory for Men (SHIM)|RADIATION: Report and compare changes in a non-inferiority analysis of the toxicities reported according to the Common Terminology Criteria for Adverse Events (CTCAE)|RADIATION: Report and compare the biochemical disease free survival (bDFS)|RADIATION: Report and compare the disease free survival (DFS)|RADIATION: Report and compare the metastase free survival (MFS)|RADIATION: Report and compare the overall survival (OS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of an Inactivated Enterovirus Type 71 Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Infection; Viral, Enterovirus
Interventions: BIOLOGICAL: Inactivated Enterovirus Type 71 Vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of GLP-1 RAs on Weight and Metabolic Indicators in Obese Patients
Status: UNKNOWN
Conditions: Obesity
Interventions: DRUG: Liraglutide|DRUG: Exenatide|DRUG: Exenatide Microspheres for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II/III Clinical Study on Inhibitory Effects of E0167 on Recurrence of Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Menatetrenone|DRUG: Menatetrenone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Contrast-enhanced vs. B-mode Ultrasound-guided Percutaneous Biopsy of Retroperitoneal Tumors
Status: COMPLETED
Conditions: Retroperitoneal Neoplasms
Interventions: PROCEDURE: CEUS-guided percutaneous biopsy|PROCEDURE: B-mode US-guided percutaneous biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Interest of the Xylocaine® and Ketamine on the Management of Acute and Chronic Ain After Colectomy by Laparoscopy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Xylocaine|DRUG: Ketamine|DRUG: isotonic saline serum intravenous administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Celecoxib vs. Acetaminophen/Codeine/Caffeine for Post-operative Analgesia in Rhinoplasty.
Status: UNKNOWN
Conditions: Pain, Postoperative|Surgery--Complications|Opioid Analgesic Adverse Reaction|Opioid Use
Interventions: DRUG: Celecoxib 200mg|DRUG: Acetaminophen, Codeine Drug Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate SSD8432/Ritonavir in Adults With COVID-19
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: SSD8432 750mg|DRUG: SSD8432 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of FSGM Cloud-based Remote Intervention for Insulin-dEpendent Diabetic Patients (FRIEND)
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: OTHER: Intervention by medical staff based on a cloud system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nurse-Provided Care or Standard Care in Treating Patients With Pancreatic Cancer
Status: COMPLETED
Conditions: Fatigue|Nausea and Vomiting|Pain|Pancreatic Cancer
Interventions: OTHER: medical chart review|OTHER: questionnaire administration|PROCEDURE: fatigue assessment and management|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: MSI-78 Topical Cream vs. Oral Ofloxacin in the Treatment of Infected Diabetic Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcers
Interventions: DRUG: ofloxacin|DRUG: MSI-78
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extraordinarily Fun Training Project in Compulsory Secondary Education - Sexually Transmitted Infections
Status: NOT_YET_RECRUITING
Conditions: Chlamydia Infections|Gonorrhea|Syphilis Infection|Human Immunodeficiency Virus (HIV)|Human Papillomavirus (HPV)|Gender Equity
Interventions: BEHAVIORAL: Participatory teaching group|BEHAVIORAL: Sham control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Implementation Trial of Predictive Modeling to Enhance Diagnosis and Improve Treatment in Pediatric Septic Shock
Status: COMPLETED
Conditions: Sepsis|Septic Shock|Emergencies
Interventions: OTHER: Septic Shock Clinical Decision Support|OTHER: Clinical Diagnosis Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Tamoxifen Citrate or Z-Endoxifen Hydrochloride in Treating Patients With Locally Advanced or Metastatic, Estrogen Receptor-Positive, HER2-Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Breast Carcinoma|Stage III Breast Cancer AJCC v7|Stage IIIA Breast Cancer AJCC v7|Stage IIIB Breast Cancer AJCC v7|Stage IIIC Breast Cancer AJCC v7|Stage IV Breast Cancer AJCC v6 and v7
Interventions: DRUG: Endoxifen Hydrochloride|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Tamoxifen Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serotonin Transporter Inhibitor Escitalopram in Pulmonary Hypertension
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation With rTMS in Dysphagic Patients With Stroke
Status: COMPLETED
Conditions: Transcranial Magnetic Stimulation
Interventions: DEVICE: repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glucose Metabolism Effects of Vitamin D Supplementation in Prediabetes
Status: COMPLETED
Conditions: Prediabetic State|Overweight|Obese
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Vitamin D 80
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Adding Dexmedetomidine or Tramadol to Paracetamol- An Effort to Attenuate Catheter Related Bladder Discomfort
Status: RECRUITING
Conditions: Percutaneous Nephrolithotripsy (PCNL)
Interventions: DRUG: Dexmedetomidine 0.5 mic/kg|DRUG: Tramadol 1mg/kg|DRUG: Paracetamol 10mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Cardiac Insufficiency BIsoprolol Study in Japanese Patients With Chronic Heart Failure (CIBIS-J)
Status: UNKNOWN
Conditions: Chronic Heart Failure
Interventions: DRUG: Bisoprolol|DRUG: Carvedilol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet-rich Plasma vs. Whole Blood for Gluteus Medius Tendinopathy
Status: TERMINATED
Conditions: Tendinopathy|Hip Pain
Interventions: BIOLOGICAL: PRP|BIOLOGICAL: Whole Blood|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tibial Nerve Stimulation for Faecal Incontinence
Status: UNKNOWN
Conditions: Fecal Incontinence
Interventions: PROCEDURE: Percutaneous posterior tibial nerve stimulation|PROCEDURE: Transcutaneous tibial nerve stimulation|PROCEDURE: Sham transcutaneous tibial nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robotics as a Useful Tool to Improve the Hydration of the Elderly
Status: RECRUITING
Conditions: Dehydration|Daily Fluid Intake|Urinary Infections
Interventions: DEVICE: humanoid robot|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: R-DHAP vs POLA-R-DHAP Followed by Autologous Transplant as First Salvage Treatment in Patient With Relapsed or Refractory Diffuse Large B Cell Lymphoma
Status: WITHDRAWN
Conditions: Diffuse Large B Cell Lymphoma Refractory|Diffuse Large B-cell Lymphoma Recurrent
Interventions: DRUG: R-DHAP|DRUG: Pola-R-DHAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Jinghua Weikang Capsule Containing Quadruple Therapy for IgAN With Helicobacter Pylori Infection
Status: ENROLLING_BY_INVITATION
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: JWC containing quadruple therapy|DRUG: Bismuth-containing quadruple therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measuring Sleep Quality With Puki in Hemodialysis Patients Performing Progressive Muscle Relaxant Exercises
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: BEHAVIORAL: Progressive Muscle Relaxation Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fecal Microbiota Transplantation in Crohn's Disease as Relay After Anti-TNF Withdrawal
Status: RECRUITING
Conditions: Crohn Disease
Interventions: DRUG: Fecal Microbiota Transplantation (FMT)|DRUG: Sham-transplantation (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Safety of NIPOX in Peritoneal Carcinomatosis of CRC
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Oxaliplatin|DRUG: LV5FU or Folfiri|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Wound Healing Efficacies of Different Adhesive Bandages
Status: COMPLETED
Conditions: Wound Healing
Interventions: DEVICE: Marketed Adhesive Bandage #1|DEVICE: Marketed Bandage #2|DEVICE: Non-Marketed Bandage #1|DEVICE: Non-Marketed Bandage #2|DEVICE: Non-Marketed Adhesive Bandage #3|DEVICE: Non-Marketed Adhesive Bandage #4|DEVICE: Non-Marketed Adhesive Bandage #5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Strong Teens for Healthy Schools Change Club: A Civic Engagement Approach to Improving Physical Activity and Healthy Eating Environments
Status: RECRUITING
Conditions: Cardiovascular Diseases|Nutrition|Physical Activity
Interventions: BEHAVIORAL: STHS Intervention|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Poractant Alfa (Curosurf®)) -- Effect in Adult Patients Diagnosed With 2019 Novel Coronavirus (SARS-COV-19; (Covid-19)) Acute Respiratory Distress Syndrome (ARDS)
Status: TERMINATED
Conditions: Acute Respiratory Distress Syndrome
Interventions: DRUG: CUROSURF® (poractant alfa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and AVD in Early-stage Unfavorable Classical Hodgkin Lymphoma
Status: COMPLETED
Conditions: Classical Hodgkin Lymphoma
Interventions: DRUG: Nivolumab|DRUG: Adriamycin|DRUG: Vinblastine|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: tES With Random Noise Stimulation Applied to Children With Brain Injury
Status: COMPLETED
Conditions: Brain Injury|Motor Skills Disorders
Interventions: DEVICE: Transcranial Random Noise Stimulation|OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of BI 695500 in Patients With Moderately to Severely Active Rheumatoid Arthritis
Status: TERMINATED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: BI 695500
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical Application of Vac Dressings In Obese Patients to Reduce Wound Complications
Status: TERMINATED
Conditions: Wound Infection, Surgical|Obesity|Postoperative Complications
Interventions: DEVICE: Prevena|DEVICE: Standard Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab Plus Modified FOLFOX6 Regimen as the Salvage Treatment in Metastatic Breast Cancer (MBC) Patients
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Avastin + mFOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weight Loss in Obese Children and Adolescents and Its Effect on Improvement of Destructive Changes in Blood Vessels
Status: UNKNOWN
Conditions: Obesity
Interventions: BEHAVIORAL: low fat and polysaccharide rich diet|BEHAVIORAL: specific physical training program for obese children
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Initiation of Colon Cancer Screening in Veterans or "Start Screening Now"
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: BEHAVIORAL: Stepped CRCS Interventions|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Comparison Efficiency of Oral Etoricoxib Versus Intravenous Fentanyl on Post Operative Pain in Curettage Under TIVA
Status: COMPLETED
Conditions: Abnormal Uterine Bleeding
Interventions: PROCEDURE: fractional curettage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Treatment With Zolpidem: Nightly and Intermittent Dosing
Status: COMPLETED
Conditions: Insomnia|Primary Insomnia|Psychophysiologic Insomnia
Interventions: DRUG: Zolpidem|DRUG: Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cytotoxic T-Lymphocytes for the Prophylaxis of Cytomegalovirus After Allogeneic Stem Cell Transplant
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: BIOLOGICAL: CMV CTL infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of AZD2014 in TSC1/2 Mutated or TSC1/2 Null GC Patients as Second-line Chemotherapy
Status: TERMINATED
Conditions: Cancer of Stomach
Interventions: DRUG: AZD2014
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PBM Effects on Health and Well-being in Humans
Status: NOT_YET_RECRUITING
Conditions: Sleep Deprivation|Circadian Rhythm Disorders
Interventions: DEVICE: PBM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Genetic Information to Inform Treatment and Screening for Prostate Cancer, GIFTS Study
Status: ENROLLING_BY_INVITATION
Conditions: Prostate Carcinoma
Interventions: BEHAVIORAL: Questionnaire|PROCEDURE: Biospecimen Collection|DIAGNOSTIC_TEST: Genetic Testing|OTHER: Genetic Counseling|OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Oral and Nasal Tube Feeding on Stroke-related Dysphagia
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Intermittent Oro-esophageal Tube Feeding|DEVICE: Nasogastric Tube Feeding|BEHAVIORAL: comprehensive rehabilitation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET With Respiratory Gating Technique in Evaluation of Response and Normal Tissue Effect in Thoracic Cancer
Status: UNKNOWN
Conditions: To Correlate RPM Respiratory-gating Methods Analyses, Treatment Response, and Normal Tissue Metabolic Effect.|Application in Clinical Outcomes and Prediction of Prognosis.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study With LJPC-401 for the Treatment of Myocardial Iron Overload in Patients With Transfusion-Dependent Beta Thalassemia
Status: TERMINATED
Conditions: Beta-Thalassemia
Interventions: DRUG: LJPC-401|DRUG: LJPC-401
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Patients With Atherosclerotic Disease With Paclitaxel-associated to LDL Like Nanoparticles
Status: UNKNOWN
Conditions: Coronary Artery Disease|Atherosclerosis|Inflammation
Interventions: DRUG: LDE-Paclitaxel|DRUG: LDE-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Icotinib and Gemcitabine as First-line Treatment in Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: icotinib|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of Anifrolumab in Adult Patients With Active Proliferative Lupus Nephritis
Status: RECRUITING
Conditions: Lupus Nephritis
Interventions: DRUG: Anifrolumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of 'R' (Electro-kinetic Beverage) on Insomnia, Fatigue, and Depression in Breast Cancer Patients Having Adjuvant Chemo
Status: TERMINATED
Conditions: Breast Cancer
Interventions: OTHER: 'R' (Electro-kinetically altered beverage)|OTHER: Placebo (water)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Study of Immunogenicity and Safety of Flu-ID Vaccine Versus Flu-IM Vaccine
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Flu-ID 15μg|BIOLOGICAL: Inactivated adjuvanted Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioavailability Investigations of Thyronajod Mite Tablets of Dosage Strengths 50 μg Levothyrox-ine/75 μg Iodine, and 100 μg Levothyroxine/75 μg Iodine vs. a Levothyroxine Drinking-Solution: A Randomised Cross Over Study in Healthy Male Individuals. Currently: 50 μg/ 75 μg Tablets
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: levothyroxine|DRUG: levothyroxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: L-arginine for Knee Osteoarthritis Patients
Status: RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: DIETARY_SUPPLEMENT: L-arginine tablet|DIETARY_SUPPLEMENT: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic Versus Laparoscopy NOSE for Stage I-III Left-sided Colon Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: PROCEDURE: Colectomy with NOSE procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Radiation and Gene Therapy Before Nivolumab for Metastatic Non-Small Cell Lung Carcinoma and Uveal Melanoma
Status: TERMINATED
Conditions: Lung Squamous Cell Carcinoma Stage IV|Nonsquamous Nonsmall Cell Neoplasm of Lung|Metastatic Uveal Melanoma
Interventions: BIOLOGICAL: ADV/HSV-tk|DRUG: Valacyclovir|RADIATION: SBRT|DRUG: nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pain Neuroscience Education and Standard Rehabilitation Regime in Patients of Carpal Tunnel Syndrome
Status: RECRUITING
Conditions: Wrist Injuries|Carpal Tunnel Syndrome
Interventions: OTHER: Pain Neuroscience education and standard rehabilitation regime|OTHER: standard Rehabilitation regime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Time-Restricted Eating on Metabolic Homeostasis, Inflammation and Oxidative Stress in Metabolic Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Metabolic Syndrome|Overweight or Obesity|PreDiabetes|Weight Loss|Quality of Life
Interventions: BEHAVIORAL: Time-Restricted Eating
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Technology Assisted Treatment for Trichotillomania
Status: NOT_YET_RECRUITING
Conditions: Trichotillomania
Interventions: BEHAVIORAL: Device and app system designed for participant to self-administer Habit Reversal Training and Stimulus Control|BEHAVIORAL: Reminder bracelet and journaling app control condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MIN PLAN VS CBT for Suicide Prevention
Status: RECRUITING
Conditions: Suicide Risk
Interventions: BEHAVIORAL: Young Adults Culturally Adapted Manual Assisted Psychological Therapy (YA-CMAP)|DEVICE: Min Plan Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Fentanyl on the Rate of Anesthesia
Status: COMPLETED
Conditions: Painful Irreversible Pulpitis
Interventions: DRUG: Lidocaine with Epinephrine+ Normal saline|DRUG: Lidocaine with Epinephrine + fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene
Status: ACTIVE_NOT_RECRUITING
Conditions: X-Linked Retinitis Pigmentosa
Interventions: BIOLOGICAL: Genetic: AAV5-hRKp.RPGR|BIOLOGICAL: Genetic: AAV5-hRKp.RPGR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Observational, Multicentre, 2 Year Study Evaluating the Use of Eylea (Aflibercept) for the Treatment of Neovascular (Wet) Age-related Macular Degeneration in UK NHS Opthalmology Clinics
Status: TERMINATED
Conditions: Wet Age-related Macular Degeneration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Severe Decrease of Growth Velocity in Children With Anorexia Nervosa.Therapeutic Trial of Growth Hormone
Status: COMPLETED
Conditions: Anorexia Nervosa|Interruption of Growth|Delayed Puberty|Osteopenia With Failure of Acquisition of Bone Mass
Interventions: DRUG: SOMATROPINE* : Norditropine® simplexx®|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of RoActemra/Actemra (Tocilizumab) Plus DMARDs in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab [RoActemra/Actemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Belatacept With Early Steroid Withdrawal rATG and Everolimus in Renal Transplantation (BETTER Trial)
Status: UNKNOWN
Conditions: Kidney Transplant Rejection
Interventions: DRUG: Belatacept|DRUG: Everolimus|DRUG: mycophenolate mofetil|DRUG: corticosteroids|DRUG: rabbit antithymocyte globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Follow-up Study of Children Previously Primed With GSK Pneumococcal Vaccine (GSK1024850A) and of Unprimed Children
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Pneumococcal vaccine GSK1024850A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cabergoline for Lactation Inhibition After Second-Trimester Abortion or Loss
Status: COMPLETED
Conditions: Lactation Suppressed
Interventions: DRUG: Cabergoline 1 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Enamel Demineralization by Use of K18-smooth Surface Sealant
Status: COMPLETED
Conditions: Dental Caries
Interventions: DEVICE: UDMA-K18 smooth surface sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of LY3457263 Alone and in Combination With Dulaglutide (LY2189265) in Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY3457263|DRUG: Placebo|DRUG: Dulaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Piperacillin/Tazobactam Versus Carbapenems in Non-bacteremic UTI Due to -ESBL-producing Enterobacteriaceae
Status: UNKNOWN
Conditions: Urinary Tract Infections|Enterobacteriaceae Infections|Infection Due to ESBL Bacteria|Carbapenem|Escherichia Coli Infection|Klebsiella Pneumoniae Infection|Clinical Trial|Drug Resistance, Bacterial
Interventions: DRUG: Meropenem|DRUG: Ertapenem 1000 MG|DRUG: Piperacillin, Tazobactam 4-0.5G Solution for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Antiresorptive Efficacy Discontinuation of Denosumab
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoporosis, Postmenopausal|Osteoporosis
Interventions: DRUG: denosumab|DRUG: alendronate|DRUG: raloxifene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Air Q Laryngeal Airway Versus the AmbuAura Gain as a Conduit for Endotracheal Intubation
Status: NOT_YET_RECRUITING
Conditions: Difficult Intubation
Interventions: DEVICE: cook ®Airway Exchanger Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Central Glutathione Levels in Women With Late Life Depression: a Cross Sectional Pilot Feasibility Study
Status: WITHDRAWN
Conditions: Female, Late Life Depression
Interventions: OTHER: A 3 Tesla MRI scanner (Siemens, Erlangen Germany), will be used to measure levels of GSH in the brain.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison Study Between Nellcor Respiration Rate Technology (RRoxi) and Masimo Acoustic Respiration Rate (RRa)
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Radical-7|DEVICE: Nellcor™ Bedside Respiratory Patient Monitoring System|DEVICE: Capnostream 20p
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Evaluate the Use of the Foundation Pain Index and the Nutritional Supplement BioPlete™ in Adults With Chronic Pain
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DIETARY_SUPPLEMENT: BioPlete™ Advanced Formula|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: INO-3107 With Electroporation (EP) in Participants With HPV-6- and/or HPV-11-Associated Recurrent Respiratory Papillomatosis (RRP)
Status: COMPLETED
Conditions: Respiratory Papillomatosis
Interventions: DRUG: INO-3107|DEVICE: CELLECTRA™ 2000
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Triathlon - A New Total Knee Prosthesis System - Triathlon PA vs. Triathlon Pressfit
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee
Interventions: DEVICE: Triathlon PA|DEVICE: Triathlon Pressfit
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determining the Impact of a Physiotherapist-Led Primary Care Model for Hip and Knee Pain - A Pilot Trial
Status: RECRUITING
Conditions: Hip Osteoarthritis|Knee Osteoarthritis
Interventions: OTHER: Physiotherapist-led primary care model for hip and knee pain|OTHER: Usual physician-led primary care model for hip and knee pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT