pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparing Manipulation, Rehabilitation and Combination of the Two in the Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Full Kinetic Chain Manipulative Therapy|OTHER: Full Kinetic Chain Rehabilitation|OTHER: Full Kinetic Chain Manipulative Therapy with Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy of N-acetylcysteine (NAC) in the Treatment of the Common Cold and Cough
Status: COMPLETED
Conditions: Common Cold Associated With Cough
Interventions: DRUG: N-acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CONTAIN COVID-19: Convalescent Plasma to Limit COVID-19 Complications in Hospitalized Patients
Status: COMPLETED
Conditions: COVID-19|Coronavirus|Coronavirus Infection
Interventions: BIOLOGICAL: Convalescent Plasma|OTHER: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Bronchitol in Bronchiectasis
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: DRUG: Mannitol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of HB0017 in Patients With Moderate to Severe Plaque Psoriasis
Status: RECRUITING
Conditions: Psoriasis
Interventions: BIOLOGICAL: HB0017 Q4W|BIOLOGICAL: HB0017 Q8W|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ABR-217620 in Patients With Advanced Non-Small Cell Lung Cancer, Renal Clear Cell Carcinoma or Pancreatic Cancer
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma|Renal Cell Carcinoma|Pancreatic Cancer
Interventions: DRUG: ABR-217620
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Immunogenicity and Safety of CSL's 2012/2013 Formulation of Enzira® Vaccine in Healthy Volunteers
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: CSL Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study on the Effects of Soy Protein on Blood Lipids in Men and Women With Mild to Moderate Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Soy protein; 25 grams/day|DIETARY_SUPPLEMENT: Control protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Fecal Microbial Transplantation Treatment in Adults With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: Fecal Microbial Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Tolerability of PF-05089771 Will be Investigated in Healthy Subjects Over a 14 Day Dosing Period.
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: PF-05089771|DRUG: PF-05089771|DRUG: PF-05089771|DRUG: PF-05089771
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Serum and Urine Titanium Levels in Children With Early Onset Scoliosis Treated With Growth-Sparing Instrumentation
Status: COMPLETED
Conditions: Early-Onset Scoliosis Deformity of Spine
Interventions: COMBINATION_PRODUCT: Growth-sparing instrumentation and titanium levels
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diagnosing Frontotemporal Lobar Degeneration
Status: UNKNOWN
Conditions: Corticobasal Syndrome|Progressive Supranuclear Palsy|Behavioral Variant Frontotemporal Dementia|Semantic Dementia|Progressive Nonfluent Aphasia|Amyotrophic Lateral Sclerosis and/or Frontotemporal Dementia
Interventions: OTHER: Observational Study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study in Healthy Adults Evaluating PF-07202954
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease|Liver Fibrosis
Interventions: DRUG: PF-07202954 Repeat Dose|DRUG: PF-07202954 Single Dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Pharmacokinetics of PEP005 (Ingenol Mebutate) Gel, 0.05%, When Applied in a Maximal Use Setting to the Dorsal Aspect of the Forearm in Patients With Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: PEP005 (ingenol mebutate) Gel, 0.05%|DRUG: Vehicle Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Routine Cervical Dilatation at the Non-labour Caesarean Section and Its Influence on Postoperative Pain
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: PROCEDURE: Cervical dilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Kinetics of Nasal Cytokine Responses to Mechanical Stimulation
Status: COMPLETED
Conditions: Allergic Rhinitis Due to Grass Pollen|Allergic Asthma
Interventions: OTHER: Nasal Secretion Sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cause-effect Relationships Between Brain Networks and Bimanual Coordination in Older Adults
Status: UNKNOWN
Conditions: Healthy Aging|Healthy
Interventions: DEVICE: HD-tACS|DEVICE: sham HD-tACS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pemetrexed Plus Oxaliplatin as Adjuvant Chemotherapy for Radically Resected Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Pemetrexed/Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tooth Autotransplantation and Bone Dimension Changes
Status: UNKNOWN
Conditions: Bone Loss, Alveolar|Tooth Loss|Bone Atrophy, Alveolar
Interventions: PROCEDURE: AUTOTRANSPLANTATION TOOTH
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Management of Breathlessness in Patients With Lung Cancer
Status: COMPLETED
Conditions: Breathlessness|Dyspnea|Lung Cancer
Interventions: BEHAVIORAL: Cognitive Behavioral Intervention for Breathlessness
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Feasibility of an eHealth Intervention for Pregnant Women on Diet, Physical Activity and Knowledge Related to Pregnancy
Status: ACTIVE_NOT_RECRUITING
Conditions: Pregnancy Related
Interventions: BEHAVIORAL: App intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MEN1703 (SEL24) to Treat Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma (JASPIS-01)
Status: NOT_YET_RECRUITING
Conditions: Non-Hodgkin Lymphoma, B-cell
Interventions: DRUG: MEN1703|DRUG: Glofitamab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Active Drug Comparative Trial to Evaluate the Antiviral Activity and Safety in Chronic Hepatitis B Patients
Status: UNKNOWN
Conditions: Hepatitis B, Chronic
Interventions: DRUG: EntecaBell ODT. 0.5mg|DRUG: Baraclude Tab. 0.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Adenosine to Determine the Electrophysiological Mechanism of Premature Ventricular Contractions
Status: RECRUITING
Conditions: Premature Ventricular Contraction (PVC)
Interventions: DRUG: Adenosine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Duration of Music Interventions and Pain Tolerance (DOMINANT)
Status: RECRUITING
Conditions: Pain, Acute
Interventions: OTHER: Listening to music for 1 minute|OTHER: Listening to music for 5 minutes|OTHER: Listening to music for 20 minutes|OTHER: Not listening to music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ankle Robotics After Stroke
Status: RECRUITING
Conditions: Foot Drop|Stroke|Hemiparesis
Interventions: DEVICE: PTR Physical Therapy while wearing Robot group (Phase II)|OTHER: Physical Therapy Only (Phase II)|DEVICE: Cross over group for Physical Therapy n Sub-Acute group. (Phase II)|DEVICE: Chronic Stroke Subjects to receive robotic gait training therapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Teenage/Young Adults (TYA) and Paediatric Patients With ALK Positive Cancers
Status: RECRUITING
Conditions: Solid Tumor|Haematological Malignancy|Malignant Neoplasm|Lymphoproliferative Disorders|Neoplasms by Histologic Type|Neoplasms by Site|Cancer|Anaplastic Large Cell Lymphoma|Lymphoma|Renal Cell Carcinoma|Neuroblastoma
Interventions: DRUG: Alectinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The International Polycap Study 3 (TIPS-3)
Status: COMPLETED
Conditions: Cardiovascular Disease|Fractures|Cancers
Interventions: DRUG: Polycap|DRUG: Aspirin|DRUG: Vitamin D|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Trial:the Effect of Liquid Food on the Intake of Energy and Protein in Malignant Hematologic Patients
Status: COMPLETED
Conditions: Hematological Disease|Delayed Gastric Emptying|Malignant Disease
Interventions: OTHER: dietary counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Long-term Safety of the Combination Product QVA149A Against Placebo and Standard of Care Treatment in Chronic Obstructive Pulmonary Disease Patients With Moderate to Severe Airflow Limitation
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: QVA149|DRUG: Tiotropium|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Combination of Immunotherapy and Neoadjuvant Chemoradiotherapy in MSS Locally Advanced Rectal Cancer
Status: UNKNOWN
Conditions: Locally Advanced Rectal Cancer
Interventions: DRUG: PD-1 antibody|DRUG: Capecitabine|DRUG: Irinotecan|RADIATION: Neoadjuvant Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PEEP Incremental and Decremental Alveolar Recruitment of Critically Ill Corona Virus Disease-19 (COVID-19) Patients
Status: COMPLETED
Conditions: COVID-19|Virus; Pneumonia|Atelectasis
Interventions: PROCEDURE: alveolar recruitment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of the Safety and Efficacy of Ustekinumab (CNTO 1275) in Patients With Moderate to Severe Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Placebo; Ustekinumab (CNTO 1275) 45 or 90 mg|DRUG: Ustekinumab (CNTO 1275) 45 mg|DRUG: Ustekinumab (CNTO 1275) 90 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Eggplant Extract on Lipid Profile During Fasting and Postprandial Period
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: Eggplant extract|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Sunflower Syndrome With ZX008 (Fenfluramine Hydrochloride) in Children and Young Adults (Ages 4-25).
Status: ACTIVE_NOT_RECRUITING
Conditions: Photosensitive Epilepsy
Interventions: DRUG: Fenfluramine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dyadic Intervention for Psychological Distress of Patients With Colorectal Cancer and Their Spouses
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: OTHER: 6-week dyadic intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pain Study to Assess Local Anesthetic Efficacy and Safety of CTY-5339 on Gingival Mucosal Tissue in Normal Volunteers
Status: COMPLETED
Conditions: No Disease State or Condition
Interventions: COMBINATION_PRODUCT: One spray CTY-5339-A|DEVICE: One spray CTY-5339-CB|DEVICE: One spray CTY-5339-P
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Bevacizumab to Treat Kaposi's Sarcoma in HIV-Positive and HIV-Negative Patients
Status: COMPLETED
Conditions: Kaposi's Sarcoma|HIV Infections|HIV Seronegativity
Interventions: BIOLOGICAL: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hardware Wound Healing In Surgical Treatment Of Sacrococcygeal Pilonidal Sinus Disease
Status: COMPLETED
Conditions: Sacrococcygeal Pilonidal Sinus Disease
Interventions: DEVICE: Hardware wound healing|DEVICE: Usual Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Fetal Endoscopic Surgery for Spina Bifida
Status: RECRUITING
Conditions: Neural Tube Defects|Spina Bifida, Open|Myelomeningocele|Fetal Disease|Hydrocephalus|Chiari Malformation Type 2|Congenital Abnormality|Surgery; Maternal, Uterus or Pelvic Organs, Affecting Fetus
Interventions: PROCEDURE: Fetoscopic repair of spina bifida
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melphalan on Disease Burden Measured by Next Generation Sequencing Before AHCT (Autologous Hematopoietic Cell Transplant) for Multiple Myeloma
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: Evomela|DEVICE: Next Generation Sequencing|DRUG: Prochlorperazine|DRUG: Acetaminophen|DRUG: Diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Safety of ABT-308 in Healthy Volunteers and Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: ABT-308|DRUG: ABT-308|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of LDRT Plus Concurrent Partial SBRT and Tislelizumab in Patients With Bulky Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: Tislelizumab|RADIATION: Low Dose Radiotherapy|RADIATION: Stereotactic Ablative Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of 7 Botulinum Antitoxin Serotypes Derived From Horses
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Botulinum Antitoxin Heptavalent (A B C D E F G) - (EQUINE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Target Engagement and Response to Oxytocin
Status: ACTIVE_NOT_RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: Oxytocin nasal spray|BEHAVIORAL: Social Cognition Skills Training|BEHAVIORAL: Health Management|DRUG: Placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Motivation in Return to Work After Work Disability
Status: ACTIVE_NOT_RECRUITING
Conditions: Motivation|Quality of Life|Communication|Health Behavior
Interventions: OTHER: MI|OTHER: CAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Evaluate the Efficacy and Safety of Oral Sumatriptan for the Acute Treatment of Migraine in Children and Adolescents
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: Sumatriptan 25 mg|DRUG: Sumatriptan 50 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cryoanalgesia to Prevent Acute and Chronic Pain Following Surgery: A Randomized, Double-Masked, Sham-Controlled Study
Status: COMPLETED
Conditions: Mastectomy|Upper Limb Amputation Below Elbow|Upper Limb Amputation Above Elbow|Lower Limb Amputation Below Knee|Lower Limb Amputation Above Knee|Knee Arthropathy|Shoulder Arthroplasty|Rotator Cuff Repair|Video-Assisted Thoracoscopic Surgery (VATS)|Skin Grafting
Interventions: DEVICE: Cryoneurolysis (active)|DEVICE: Sham cryoneurolysis procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Reduced Daily Step Count and Anabolic Interventions on Muscle Protein Metabolism in Older Persons
Status: COMPLETED
Conditions: Older Adults|Muscle Protein Synthetic Response to Protein|Reduced Physical Activity
Interventions: OTHER: step-reduction|OTHER: step-reduction plus resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assess Efficacy, Immune Response & Safety of 2 Doses of Oral Live Attenuated HRV Vaccine in Healthy Infants
Status: COMPLETED
Conditions: Infections, Rotavirus
Interventions: BIOLOGICAL: Rotarix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Dose-Finding Study of MK0974 in Acute Migraine (MK0974-004)
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Comparator: Placebo|DRUG: MK0974|DRUG: MK0974|DRUG: MK0974|DRUG: MK0974|DRUG: MK0974|DRUG: MK0974|DRUG: MK0974|DRUG: Rizatriptan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy for Un-biopsied Early- Stage Non Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: RADIATION: Group 1: Peripherally Located Tumors|RADIATION: Group 2: Peripherally Located Chest Wall Adjacent Tumors|RADIATION: Group 3: Centrally Located Tumors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prognostic Value of Biomarkers Associated With Endothelial Progenitor Cells Mobilization in Acute Coronary Syndromes
Status: COMPLETED
Conditions: Acute Coronary Syndromes
Interventions: OTHER: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Toujeo Insulin in Type 2 Diabetes Patients Inadequately Control With Their Basal Insulin Treatment
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: insulin glargine (U300)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Type 2 Diabetes Intervention by Gut Microbiota-directed Diet -a Open Labelled RCT
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Quantitative Renal Uptake Using TC99m DMSA in Hypertensive &/or Diabetic Patients.
Status: UNKNOWN
Conditions: Diabetes Mellitus|Hypertension
Interventions: DIAGNOSTIC_TEST: DMSA scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Zanamivir Treatment of Vascular Permeability in Dengue (ZAP-DENGUE)
Status: RECRUITING
Conditions: Dengue Fever
Interventions: DRUG: Zanamivir|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Local Liver Treatment for Multi-organ Colorectal Cancer Metastases
Status: RECRUITING
Conditions: Metastatic Colorectal Carcinoma|Multi-organ Metastatic Colorectal Cancer|Metastatic Malignant Neoplasm in the Liver
Interventions: PROCEDURE: Radical local Surgery|DRUG: Systemic therapy|OTHER: Interventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Fructose Corn Syrup
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver Disease|Obesity
Interventions: BEHAVIORAL: High fructose corn syrup diet|BEHAVIORAL: Standard diet (low in high fructose corn syrup)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: TRA for Preventing Symptomatic Urinary Tract Infection Among High-risk Elderly Residing in Nursing Homes
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DRUG: Concentrated herbal extract granules TRA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study Comparing Superior Capsule Reconstruction Using Different Graft for Irreparable Rotator Cuff Tear
Status: UNKNOWN
Conditions: Rotator Cuff Tears
Interventions: PROCEDURE: fascia lata allograft|PROCEDURE: human dermal allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Holmium Laser Enucleation of Prostate(HOLEP) vs Greenlight(XPS) Laser Photoselective Vapo-Enucleation of Prostate(PVEP)
Status: COMPLETED
Conditions: Benign Prostate Hyperplasia
Interventions: PROCEDURE: HOLEP|PROCEDURE: PVEP-XPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CM326 in Patients With Chronic Rhinosinusitis With Nasal Polyps
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps
Interventions: DRUG: CM326|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Effects of Laser Acupuncture Therapy for OAB Women.
Status: UNKNOWN
Conditions: Overactive Bladder
Interventions: DEVICE: Verum laser acupuncture|DEVICE: Sham laser acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation for Improving Gait Training in Stroke
Status: COMPLETED
Conditions: Stroke|Cerebral Vascular Accident
Interventions: DEVICE: transcranial direct current stim (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MELATOX: Evaluation of Percutaneous Dissolvement of Melatonin When Used as Sunscreen; a Randomized, Placebo Controlled, Double-blind Crossover Study on Healthy Volunteers.
Status: COMPLETED
Conditions: Solar Skin Damage
Interventions: DRUG: Melatonin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Antithrombin Enhancement May Improve Anticoagulation Efficiency in Infants Undergoing Cardiopulmonary Bypass for Cardiac Surgery
Status: COMPLETED
Conditions: Cardiopulmonary Bypass
Interventions: DRUG: Antithrombin III|OTHER: Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Refractory Patellar Tendinopathy With Mesenquimal Trunk Cells. Comparative Study With PRP.
Status: UNKNOWN
Conditions: Patellar Tendinopathy
Interventions: PROCEDURE: mesenchymal stem cells|PROCEDURE: Pure platelet-rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reaching Better Health Study: A Website to Improve Type 2 Diabetes Self-Management
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Health & Wellness Website|OTHER: Control Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Metformin for the Prevention of Oral Cancer in Patients With Oral Premalignant Lesions
Status: TERMINATED
Conditions: Erythroplakia|Leukoplakia|Oral Cavity Carcinoma|Proliferative Verrucous Leukoplakia
Interventions: DRUG: Metformin|PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cyanophyta Aphanizomenon Flos-aquae, and Adipose Stroma Vascular Fraction, in Heart Failure Patient
Status: RECRUITING
Conditions: Congestive Heart Failure Chronic
Interventions: DIETARY_SUPPLEMENT: Water-soluble Extract of the Cyanophyta Aphanizomenon Flos-aquae (AFA),|PROCEDURE: Infiltrtion of SVf
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Obturator and Femoral Nerve Block in Patients With Hip Fracture
Status: UNKNOWN
Conditions: Hip Fractures
Interventions: DRUG: Bupivacaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine Post-Exposure Prophylaxis for Coronavirus Disease (COVID-19) Among Health-Care Workers
Status: UNKNOWN
Conditions: Coronavirus Disease 2019 (COVID-19)|Post-Exposure Prophylaxis
Interventions: DRUG: Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Anlotinib Plus Pemetrexed or Pemetrexed for Previously Untreated Elderly (>=70) or PS=2 Non-squamous NSCLC
Status: UNKNOWN
Conditions: Advanced Non-squamous NSCLC
Interventions: DRUG: Anlotinib plus Pemetrexed|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemocoagulation and Lipoperoxidation in Women Using Combined Oral Contraceptives, Correction by Antioxidants
Status: UNKNOWN
Conditions: Polycystic Ovarian Syndrome|Hyperandrogenism|Menstrual Irregularities
Interventions: DRUG: 20 mcg ethinylestradiol /3 mg drospirenone|DRUG: 20 mcg ethinylestradiol/3 mg drospirenone and Selmevit|DRUG: 30 mcg ethinylestradiol/3 mg drospirenone|DRUG: 30 mcg ethinylestradiol/3 mg drospirenone and Selmevit|DRUG: 35 mcg ethinylestradiol/2 mg cyproterone|DRUG: 35 mcg ethinylestradiol/2 mg cyproterone and Selmevit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: RCT Comparing Standard Cannula Delivered FS, UGFS and ClariVein® in the Management of SVI
Status: WITHDRAWN
Conditions: Superficial Venous Insufficiency, Varicose Veins
Interventions: DRUG: Sodium Tetradecyl Sulphate (STS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pathways Project: Kidney Supportive Care
Status: COMPLETED
Conditions: Kidney Diseases|Chronic Kidney Diseases|End Stage Renal Disease|End Stage Renal Disease on Dialysis|Chronic Kidney Disease Requiring Chronic Dialysis
Interventions: BEHAVIORAL: IHI Breakthrough Collaborative Model
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: JS001sc or JS001 Plus Chemotherapy is Indicated for Relapsed or Metastatic First-Line Non-Squamous Non Small Cell Lung Cancer（NSCLC）
Status: RECRUITING
Conditions: Recurrent Metastatic Non-Squamous Non Small Cell Lung Cancer
Interventions: DRUG: Arm1: JS001sc (360mg Subcutaneous injection) and pemetrexed/platinum-containing chemotherapy|DRUG: Arm 2: JS001 (240mg intravenous infusion) and pemetrexed/platinum-containing chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of ASP1585 in Chronic Kidney Disease Patients With Hyperphosphatemia on Hemodialysis
Status: COMPLETED
Conditions: Hyperphosphatemia|Chronic Kidney Disease
Interventions: DRUG: ASP1585|DRUG: Placebo|DRUG: Sevelamer hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Rg3-enriched Korean Red Ginseng and American Ginseng in the Management of Hypertension in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2|Hypertension
Interventions: DIETARY_SUPPLEMENT: Ginseng|DIETARY_SUPPLEMENT: Wheat Bran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Germicidal Light
Status: WITHDRAWN
Conditions: Bacterial Transmission|S.Aureus Transmission|Operating Room Exposure to S. Aureus|90-day Postoperative Surgical Site Infections, Superficial and Deep
Interventions: DEVICE: Germicidal lighting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Using Head-mounted, Eye-tracking to Compare Looking, Manual Exploration and Social Interaction During Active Locomotion
Status: RECRUITING
Conditions: Young Children With Motor Disabilities
Interventions: BEHAVIORAL: Ride-On Cars Training with Different Postures|BEHAVIORAL: Conventional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extending Omalizumab Treatment Intervals in Patients With Chronic Spontaneous Urticaria
Status: RECRUITING
Conditions: Chronic Spontaneous Urticaria|Chronic Urticaria, Idiopathic
Interventions: DRUG: omalizumab 300 mg every four weeks|DRUG: omalizumab 300 mg every six weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2801653 in Advanced Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: LY2801653|DRUG: Cetuximab|DRUG: Cisplatin|DRUG: Gemcitabine|DRUG: Ramucirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of High-dose Naloxone Following Third Molar Extraction
Status: COMPLETED
Conditions: Healthy Subjects|Hyperalgesia|Inflammations, Endodontic|Pain, Acute|Sensitization, Central
Interventions: DRUG: Naloxone|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hormone Function in Men Treated for Pain With Opioids or Placebo
Status: COMPLETED
Conditions: Chronic Pain|Osteoarthritis
Interventions: DRUG: MS Contin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CD200 Activation Receptor Ligand (CD200AR-L) and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: Treatment with hP1A8
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Hot Flushes in Asian Women With Ultra-low Dose Estradiol Patch
Status: COMPLETED
Conditions: Hot Flashes
Interventions: DRUG: Menostar (estradiol transdermal delivery system)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Titrated Oral Misoprostol Compared to Vaginal Dinoprostone for Induction of Labor
Status: UNKNOWN
Conditions: Medical Induction of Labor Affecting Fetus
Interventions: DRUG: Misotac® Sigma Pharmaceutical Industries|DRUG: Dinoprostone 3 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Pre-deployment Retraction in Decreasing Biopsy Clip Migration During Stereotactic Breast Biopsies
Status: COMPLETED
Conditions: Breast Biopsy
Interventions: DEVICE: 5mm retraction of clip deployment apparatus.|DEVICE: No retraction of clip deployment apparatus.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neuro 1 vs. Neuro 2 Sound Processors
Status: COMPLETED
Conditions: Hearing Loss, Sensorineural|Cochlear Hearing Loss
Interventions: DEVICE: Neuro 1 & Neuro 2|DEVICE: Neuro 2 & Neuro 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ultrasound-assisted Spinal Anaesthesia in Patients With Difficult Anatomical Landmarks
Status: COMPLETED
Conditions: Spinal Anesthesia
Interventions: PROCEDURE: Ultrasound guidance|PROCEDURE: Manual palpation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine With or Without Dalteparin in Treating Patients With Unresectable or Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer|Thromboembolism
Interventions: DRUG: dalteparin|DRUG: gemcitabine hydrochloride|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Integrative Manual Therapy in Babies With Deformational Plagiocephaly and Congenital Muscular Torticollis
Status: UNKNOWN
Conditions: Plagiocephaly, Nonsynostotic|Plagiocephaly, Positional|Congenital Muscular Torticollis
Interventions: PROCEDURE: Pediatric Integrative Manual Therapy and educational therapy|PROCEDURE: Stretching and educational therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of tDCS on Impulsiveness Among People Suffering From Borderline Personality Disorder
Status: UNKNOWN
Conditions: Borderline Personality Disorder|Impulsive Behavior
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention Study on Break Activities and Workers´ Psychological and Physiological Health & Performance
Status: COMPLETED
Conditions: Exposure to Nature During Lunch Breaks|Relaxation Exercises During Lunch Breaks
Interventions: BEHAVIORAL: Park walk during lunch break|BEHAVIORAL: Relaxation during lunch break
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oral Midazolam for Sedation in Esophagogastroduodenoscopy(EGD)
Status: UNKNOWN
Conditions: Conscious Sedation Failure During Procedure
Interventions: DRUG: Oral midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of Resisted Versus Balance Exercises on Cognitive And Motor Function In Patients With Mild Cognitive Impairment
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: OTHER: RESISTED EXERCISES|OTHER: BALANCE EXERCISES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: No-preparation Resin Bonded Bridges for the Replacement of Single Missing Teeth
Status: UNKNOWN
Conditions: Missing Teeth
Interventions: DEVICE: RBBs with no or minimal preparation of their abutment teeth|DEVICE: RBBs with routine tooth preparation of their abutment teeth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Paclitaxel/Cisplatin and Cisplatin/5-fluorouracil in Neo-CRT for ESCC
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma|Chemoradiation
Interventions: DRUG: neoadjuvant chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MDX-1106 in Patients With Selected Refractory or Relapsed Malignancies
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Colorectal Cancer|Malignant Melanoma|Renal Cancer|Prostate Cancer
Interventions: BIOLOGICAL: MDX-1106
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adapted Dialectical Behaviour Therapy for Adolescents With Deliberate Self-Harm: A Pre-post Observational Study
Status: COMPLETED
Conditions: Deliberate Self Harm|Borderline Personality Disorder
Interventions: BEHAVIORAL: A-DBT-A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Safety of Alpha1-Proteinase Inhibitor in Subjects With Alpha1 Antitrypsin Deficiency
Status: ENROLLING_BY_INVITATION
Conditions: Pulmonary Emphysema in Alpha-1 Antitrypsin Deficiency
Interventions: BIOLOGICAL: Alpha-1 MP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 64Cu-ATSM PET/CT in Rectum Cancer (TEP 64Cu-ATSM-Rectum)
Status: ACTIVE_NOT_RECRUITING
Conditions: Rectal Cancer
Interventions: DRUG: 64Cu-ATSM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: OCT-Angiography and Adaptive Optics in Patients With Memory Impairment
Status: RECRUITING
Conditions: Amnesia|Alzheimer Disease|Lewy Body Disease|Parkinsons Disease With Dementia
Interventions: PROCEDURE: Ophthalmological exam|PROCEDURE: Blood pressure measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of S-1 in Combination With Gemcitabine as First-Line Treatment in Patients With Advanced Biliary Tract Cancer
Status: COMPLETED
Conditions: Advanced Biliary Tract Cancer(BTC)
Interventions: DRUG: S-1/Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Ketoconazole Shampoo, 2% and Ketoconazole 2% Shampoo (RS) in the Treatment of Tinea Versicolor.
Status: COMPLETED
Conditions: Tinea Versicolor
Interventions: DRUG: Ketoconazole Shampoo, 2%|DRUG: Ketoconazole Shampoo, 2% (Reference Standard)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Safety and Efficacy Study of Isolagen Therapy in Treatment of Restrictive Burn Scars
Status: WITHDRAWN
Conditions: Restrictive Burn Scars of Joint Area
Interventions: BIOLOGICAL: Autologous Human Fibroblasts (Isolagen TherapyTM)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HTL0039732 in Participants With Advanced Solid Tumours
Status: RECRUITING
Conditions: Neoplasms|Prostatic Neoplasms, Castration-Resistant|Stomach Neoplasms|Esophageal Neoplasms|Head and Neck Neoplasms|Colorectal Neoplasms|Pancreatic Neoplasms|Lung Neoplasms|Urinary Bladder Neoplasms|Mesothelioma, Malignant|Uterine Cervical Neoplasms|Kidney Neoplasms|Sarcoma|Pheochromocytomas
Interventions: DRUG: HTL0039732 Capsules|DRUG: HTL0039732 Capsules and atezolizumab infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug to Drug Interaction Study of KBP-5074 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy|Drug Drug Interaction
Interventions: DRUG: Itraconazole|DRUG: Rifampin|DRUG: KBP-5074
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Osteochondral Allograft in the Surgical Treatment of Basal Joint Arthritis
Status: RECRUITING
Conditions: Basal Joint Arthritis
Interventions: PROCEDURE: Osteochondral Allograft|PROCEDURE: Ligament Reconstruction Tendon Interposition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single and Multiple Ascending Doses Clinical Pharmacology Study With KAR5585
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: KAR5585 Capsules|DRUG: Placebo Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Antibiotic Management Duration Following Surgery for Intravenous Drug Abuse (IVDA) Endocarditis (OPTIMAL)
Status: ENROLLING_BY_INVITATION
Conditions: Endocarditis
Interventions: DRUG: Amoxycillin, Cefalexin, Dicloxacillin, Linezolid, Levofloxacin, Rifampicin|DRUG: Ampicillin, Oxacillin, Vancomycin, Daptomycin, Ceftriaxone, Cefepime, Ceftaroline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-TNF Therapy and Nerve Conduction Studies in Ankylosing Spondylitis
Status: COMPLETED
Conditions: Anti - TNF Therapy|Ankylosing Spondylitis|Neuropathy
Interventions: DRUG: Anti-TNF agents|DRUG: Conventional therapy users for the last 5 years
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Therapeutic Strategies in Patients With Non-squamous Non-small Cell Lung Cancer With Brain Metastases
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer Metastatic|Non-small Cell Lung Cancer|Adenocarcinoma of Lung Metastatic to Brain|Cerebral Metastases
Interventions: DRUG: Cisplatin|DRUG: Pemetrexed|DRUG: Bevacizumab|RADIATION: Cerebral Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ATS 3f(r) Aortic Bioprosthesis Model 1000 Post Approval Study
Status: TERMINATED
Conditions: Heart Valve Diseases
Interventions: DEVICE: ATS 3f Aortic Bioprosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter National Randomized Controlled Open Label Study Assessing Interest of Non Invasive Ventilation in out-of Hospital Setting During Acute Respiratory Failure in Chronic Obstructive Pulmonary Disease Patients. VeNIS BPCO
Status: UNKNOWN
Conditions: Acute Respiratory Failure|Exacerbation of COPD|Non Invasive Positive Pressure Ventilation|Out of Hospital Setting
Interventions: OTHER: Non invasive ventilation|OTHER: conventional medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT