pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of Oral Activated Charcoal on Antimalarial Drug's Ability to Kill Parasites in Malian Children With Malaria
Status: COMPLETED
Conditions: Malaria|Severe Malaria
Interventions: DRUG: Actidose Aqua|DRUG: Artesunate|DRUG: Amodiaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label, Multi-Center, Two-Part, Ph1 Study to Characterize the PKs of an Intravenous Micro-Dose of [14C]-Tazemetostat (EPZ 6438) and the ADME of an Oral [14C]-Labeled Dose of Tazemetostat in Subjects With B-Cell Lymphomas or Adv Solid Tumors
Status: COMPLETED
Conditions: Diffuse Large B Cell Lymphoma|Primary Mediastinal Lymphoma|Mantle-Cell Lymphoma|Follicular Lymphoma|Marginal Zone Lymphoma|Advanced Solid Tumors
Interventions: DRUG: Tazemetostat and [14C] Tazemetostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Progesterone Reduces Wakefulness in Sleep EEG and Has no Effect on Cognition in Healthy Postmenopausal Women
Status: COMPLETED
Conditions: Healthy|Postmenopausal
Interventions: DRUG: progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of Apatinib Plus CIK as the Third Line Therapy for Advanced Lung Adenocarcinoma Patients With Wild-Type EGFR
Status: ACTIVE_NOT_RECRUITING
Conditions: Adenocarcinoma of Lung
Interventions: BIOLOGICAL: Cytokine-Induced Killer Cells|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Calcifediol (Hy.D 25 SD/S) and Vitamin D3 on Muscle Strength in a Frail Elderly Population
Status: COMPLETED
Conditions: Deficiency, Vitamin D|Elderly, Frail
Interventions: DIETARY_SUPPLEMENT: Calcifediol 10ug/day|DIETARY_SUPPLEMENT: Vitamin D3 20ug/day|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation for the Treatment of Post-knee Arthroplasty Chronic Pain.
Status: RECRUITING
Conditions: Chronic Post-surgical Pain|Chronic Post Operative Pain|Chronic Knee Pain
Interventions: PROCEDURE: Radiofrequency ablation of peripheral nerves.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cabazitaxel and Prednisone in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer
Status: TERMINATED
Conditions: Hormone-Resistant Prostate Cancer|Stage IV Prostate Adenocarcinoma
Interventions: DRUG: Cabazitaxel|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron in Congestive Heart Failure
Status: TERMINATED
Conditions: Heart Failure|Iron Deficiency|Anemia
Interventions: DRUG: ferric carboxymaltose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enfortumab Vedotin and Pembrolizumab Combined With Radiotherapy in Muscle Invasive Bladder Cancer
Status: NOT_YET_RECRUITING
Conditions: Bladder Cancer|Muscle-Invasive Bladder Carcinoma|Stage II Bladder Cancer AJCC v8|Stage IIIA Bladder Cancer AJCC v8
Interventions: DRUG: Enfortumab Vedotin|BIOLOGICAL: Pembrolizumab|RADIATION: Intensity Modulated Radiation Therapy (IMRT)|PROCEDURE: Transurethral Resection of Bladder Tumor|PROCEDURE: Cystoscopy (CS)|PROCEDURE: Computed Tomography (CT)|PROCEDURE: Magnetic Resonance Imaging (MRI)|PROCEDURE: Positron Emission Tomography (PET)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery in Treating Patients With Liver Metastasis From a Gastrointestinal Stromal Tumor
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumor|Metastatic Cancer
Interventions: PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research Evaluating Sports ConcUssion Events - Rapid Assessment of Concussion and Evidence for Return
Status: COMPLETED
Conditions: Concussion, Brain|Motor Vehicle Accident
Interventions: DIAGNOSTIC_TEST: Clinical assessment (SCAT5)|DIAGNOSTIC_TEST: ImPACT|BEHAVIORAL: CANTAB|DIAGNOSTIC_TEST: I-PAS/Dx100|BIOLOGICAL: Saliva sample|OTHER: fMRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Transversus Abdominis Plane Block With Compound Lidocaine on Pain After Gynecological Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Normal saline|DRUG: Ropivacaine|DRUG: Compound lidocaine at low concentration|DRUG: Compound lidocaine at high concentration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Drug Interaction Study of GBT440 With Caffeine, S-warfarin, Omeprazole, and Midazolam in Healthy Subjects
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: GBT440
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Tools for Predicting Capillary Leak Shock During Dengue Fever
Status: UNKNOWN
Conditions: Dengue Fever|Children|Adults
Interventions: OTHER: For each routine sample, an additional tube will be collected to measure the osmotic pressure in the blood and urine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: TPO-RAs Combined With Anti-CD20 Antibody in the Treatment of Adult Immune Thrombocytopenia With Autoantibodies
Status: RECRUITING
Conditions: Immune Thrombocytopenia (ITP)|Autoantibodies|Evan Syndrome|Connective Tissue Diseases
Interventions: DRUG: Combined use of TPO-RAs with low-dose anti-CD20 antibody|DRUG: The best available therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CA-4948 in Combination With FOLFOX/PD-1 Inhibitor +/- Trastuzumab for Untreated Unresectable Gastric and Esophageal Cancer
Status: RECRUITING
Conditions: Gastric Cancer|Esophageal Cancer|Stomach Cancer|Esophagus Cancer|Gastroesophageal Junction Cancer
Interventions: DRUG: CA-4948|BIOLOGICAL: Nivolumab|BIOLOGICAL: Pembrolizumab|DRUG: Trastuzumab|DRUG: mFOLFOX7
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention Study to Improve Life and Care for People With Dementia and Their Caregivers in Primary Care
Status: UNKNOWN
Conditions: Dementia
Interventions: OTHER: Implementation of Dementia Care Manager
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Development and Usability Testing of a Progressive WebApp for Women With Heart Disease
Status: UNKNOWN
Conditions: Pain|Cardiac Ischemia|Women|Pain, Chronic
Interventions: BEHAVIORAL: at heart (changed from HEARTPA♀N during usability testing)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: EHR-Based and Fax-Based Referral to a Tobacco Quitline: A Comparative Study
Status: COMPLETED
Conditions: Tobacco Use Cessation|Tobacco Smoking
Interventions: BEHAVIORAL: Tobacco quitline EHR referral|BEHAVIORAL: Tobacco quitline Fax referral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictive and Diagnostic Value of Tau and Beta-amyloid Markers in the Dementia of Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease|Parkinson-Dementia Syndrome
Interventions: OTHER: [F18]-FDDNP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Postoperative Fatigue and Nausea Related to Choice of Anaesthetic Regimens
Status: COMPLETED
Conditions: Fatigue|Nausea
Interventions: DRUG: Propofol|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Early Enteral Nutrition Feeding Process Assisted by Gastrointestinal Ultrasonography
Status: UNKNOWN
Conditions: Critical Illness|Acute Gastrointestinal Injury
Interventions: OTHER: Implement nutrition therapy according a procedure assisted by gastrointestinal ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Small Bowel Cleansing for Capsule Endoscopy in Pediatric Patients
Status: UNKNOWN
Conditions: Capsule Endoscopy
Interventions: BEHAVIORAL: DIET|DRUG: polyethylene glycol 4000 solution with simethicon|DRUG: simethicon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: VNP40101M and Temozolomide in Treating Patients With Progressive or Relapsed Malignant Glioma
Status: TERMINATED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: CLORETAZINE|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incentives to Decrease Opioid Use - Pilot
Status: COMPLETED
Conditions: Substance-Related Disorders|Opioid-Related Disorders|Behavior Therapy
Interventions: BEHAVIORAL: App + Inputs Contingency Management|BEHAVIORAL: App + Outcomes Contingency Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study With Blinatumomab in Pediatric and Adolescent Patients With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: Blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen Therapy for Post-Concussion Syndrome
Status: RECRUITING
Conditions: Post-Concussion Syndrome
Interventions: DEVICE: Hyperbaric Oxygen Treatment|OTHER: Placebo gas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Weekly Docetaxel Plus Cisplatin Followed by Gemcitabine vs. Gemcitabine Plus Cisplatin Followed by Weekly Docetaxel in the Treatment of Advanced Non-Small-Cell Lung Cancer
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Taxotere, Cisplatin, Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Purpose of This Study is to Evaluate the Efficacy and Safety of Sintilimab in Combination With Xelox as Neoadjuvant Therapy for Patients With Resectable Locally Advanced Gastric or Gastroesophageal Adenocarcinoma.
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Sintilimab|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Azacitidine for the Treatment of Relapsed or Refractory T-cell Large Granular Lymphocytic Leukemia
Status: RECRUITING
Conditions: T-Cell Large Granular Lymphocyte Leukemia
Interventions: DRUG: Oral Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2 Positive Breast Cancer
Interventions: DRUG: Tucatinib|DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Combination product: Trastuzumab + Pertuzumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Upfront and Maintenance Obinutuzumab in Mantle Cell Lymphoma Treated by DHAP and MRD Driven Maintenance
Status: ACTIVE_NOT_RECRUITING
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Obinutuzumab|DRUG: Dexamethasone|DRUG: Aracytine|DRUG: Cisplatinum|DRUG: Etoposide|DRUG: Melphalan|DRUG: Carmustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Mixed Grain on Blood Glucose and Insulin in Healthy Male
Status: COMPLETED
Conditions: Healthy People|Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Mixed grain 1|DIETARY_SUPPLEMENT: Mixed grain 2|DIETARY_SUPPLEMENT: White rice|OTHER: Glucose solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Lotemax Ophthalmic Suspension 0.5%
Status: COMPLETED
Conditions: Conjunctivitis, Seasonal Allergic|Conjunctivitis, Giant Papillary|Inflammation
Interventions: DRUG: Loteprednol Etabonate|DRUG: Prednisolone Acetate 1% Oph Susp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Tolerability Study of Doripenem Compared With Meropenem in Children Hospitalized With Complicated Intra-abdominal Infections
Status: TERMINATED
Conditions: Abscess, Intra-Abdominal|Abdominal Abscess|Abdomen, Acute|Abdominal Pain|Appendicitis|Rupture|Infection|Intestinal Perforation|Peritonitis|Ileus
Interventions: DRUG: Doripenem|DRUG: Meropenem placebo|DRUG: Meropenem|DRUG: Doripenem placebo|DRUG: Amoxicillin/clavulanate potassium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enteral vs. Oral Nutrition After Pancreatoduodenectomy
Status: RECRUITING
Conditions: Pancreaticoduodenectomy|Malnutrition|Postoperative Complications
Interventions: DIETARY_SUPPLEMENT: Early enteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Identifying Risk Factors (RF) for Early Haemodialysis Arteriovenous Fistula Failure (eAVFF)
Status: COMPLETED
Conditions: Arteriovenous Fistula|Hemodialysis|End Stage Chronic Renal Failure
Interventions: OTHER: Identification of predictive factors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison of the Effectiveness and Safety of Topiramate and Phenytoin in Patients With New Onset Epilepsy Requiring Rapid Initiation of Antiepileptic Drug Treatment
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: topiramate, phenytoin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Arresting Vertical Transmission of Hepatitis B Virus
Status: COMPLETED
Conditions: Hepatitis B|Vertical Transmission of Infectious Disease
Interventions: DRUG: Tenofovir Disoproxil Fumarate|BIOLOGICAL: Monovalent HBV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: HIFU Treatment of Cutaneous Neurofibromas in Neurofibromatosis Type 1: Safety and Efficacy
Status: ACTIVE_NOT_RECRUITING
Conditions: Cutaneous Neurofibroma
Interventions: DEVICE: TOOsonix System ONE-M
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Power Thulium Vaporization vs Transurethral Resection of the Prostate for Treatment of BPH
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: PROCEDURE: M-TURP|PROCEDURE: THUVAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics Similarity of CBP-201 in Healthy Adult Chinese Subjects
Status: COMPLETED
Conditions: Healthy Adult Subjects
Interventions: BIOLOGICAL: Test drug (T1): CBP-201 injection (pre-filled syringe, 150 mg/1 mL)|BIOLOGICAL: Test drug (T2): CBP-201 injection (pre-filled syringe, 300 mg/2 mL)|BIOLOGICAL: Reference drug (R): CBP-201 injection (vial, 150 mg/1 mL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Rollover Study for Patients Who Received Tremelimumab in Other Protocols, to Allow the Patients Access to Tremelimumab Until This Agent Becomes Commercially Available or Development is Discontinued.
Status: COMPLETED
Conditions: Colorectal Neoplasms|Melanoma|Prostatic Neoplasms|Renal Cell Carcinoma|Neoplasms|Patients Who Have/Have Had Melanoma and Other Tumors
Interventions: DRUG: CP-675,206 (Tremelimumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Combination of Adductor Canal Block and Periarticular Injection. A Novel Technique for Patients Undergoing Total Knee Replacement (ACB PAI)
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Bupivacaine|DRUG: Morphine|DRUG: Methylprednisolone|DRUG: Cefazolin|DRUG: Normal saline|DRUG: Midazolam|DRUG: Propofol|DRUG: Dexamethasone|DEVICE: 8 MHz. Chiba needle, 22 G / 4 inches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Glidescope Videolaryngoscope and Macintosh Laryngoscope in Children
Status: COMPLETED
Conditions: Anesthesiology|Pediatrics
Interventions: DEVICE: Endotracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: LMA® Gastro Airway Versus Gastro-Laryngeal Tube in Endoscopic Retrograde Cholangiopancreatography
Status: COMPLETED
Conditions: Supraglottic Airway Efficiency|Airway Complication of Anesthesia|Airway Aspiration|Complication of Anesthesia|Esophagus Injury|Endoscopic Ergonomics|ERCP Airway Management
Interventions: DEVICE: Comparison of LMA Gastro Airway® and Gastro-Laryngeal Tube in patients who will undergo biliopancreatic procedures.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Walking Apnea at High Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function
Status: RECRUITING
Conditions: Pain|Hypoxia|Hypercapnia|Apnea
Interventions: OTHER: Voluntary apnoea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CART-123 FOR Relapsed/Refractory Acute Myelocytic Leukemia（AML）
Status: UNKNOWN
Conditions: Leukemia, Myeloid, Acute
Interventions: BIOLOGICAL: CART-123 cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Two Treatments for the Treatment of Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: roflumilast cream 0.3%|DRUG: Zoryve|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention Trial to Reduce Mental Health Disparities in Latina Immigrant Women
Status: COMPLETED
Conditions: Stress|Depression|Anxiety
Interventions: BEHAVIORAL: Amigas Latinas Motivando el Alma (ALMA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Chlorohexidine Gel on Tissue Healing Following Surgical Exposure of Dental Implants
Status: UNKNOWN
Conditions: Implant Infection|Bone Loss
Interventions: DRUG: Corsodyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of Systolic Heart Failure Treatment of IvabRadine Hemisulfate Sustained-release Tablets （FIRST）
Status: UNKNOWN
Conditions: Chronic Systolic Heart Failure
Interventions: DRUG: IvabRadine hemisulfate Sustained-release Tablets|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Hepatitis C Virus (HCV) Polymerase Inhibitor Pro-Drug in Combination With PEGASYS With or Without COPEGUS in Patients With Chronic Hepatitis C (CHC) Genotype 1 Infection.
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Copegus|DRUG: PEGASYS|DRUG: RO5024048 1500mg|DRUG: RO5024048 3000mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Therapeutic Ablation Versus Cardioversion for AF
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation|Cardiac Arrhythmia
Interventions: PROCEDURE: DC Cardioversion|PROCEDURE: Pulmonary vein isolation|DEVICE: Implantable loop recorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Remifentanil for Preventing Propofol Injection Pain in Elderly Patients
Status: COMPLETED
Conditions: Drug Usage
Interventions: DRUG: Remifentanil|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Single Dose Escalation Study In Healthy Volunteers To Determine The Pharmacokinetics, Safety And Tolerability Of PF-05089771 In Healthy Volunteers
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: PF-05089771|DRUG: PF-05089771|DRUG: PF-05089771|DRUG: PF-05089771|DRUG: PF-05089771|DRUG: PF-05089771
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Physiological Effect of High Flow Oxygen Therapy
Status: UNKNOWN
Conditions: High-flow Nasal Cannula|Non-invasive Positive Pressure Ventilation|Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: HFNC|DEVICE: NPPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Meditation in Bone Marrow Transplantation
Status: COMPLETED
Conditions: Hematologic Malignancy|Bone Marrow Transplantation|Stem Cell Transplantation
Interventions: BEHAVIORAL: Mindfulness training|BEHAVIORAL: Nurse education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: nTMS for Motor Mapping of Rolandic Lesions
Status: COMPLETED
Conditions: Glioma|Brain Metastases
Interventions: PROCEDURE: nTMS data available for the surgeon|PROCEDURE: nTMS data not available for the surgeon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Dose Ranging Study of Celivarone With Amiodarone as Calibrator for the Prevention of Implantable Cardioverter Defibrillator (ICD) Interventions or Death
Status: COMPLETED
Conditions: Arrhythmia Prophylaxis|Ventricular Arrhythmia
Interventions: DRUG: Celivarone|DRUG: Amiodarone|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Efficacy of Tor Kinase Inhibitor in Liver Cancer Patients
Status: COMPLETED
Conditions: Cancer|Advanced Hepatocellular Carcinoma
Interventions: DRUG: AZD8055
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxycycline Treatment in Mild Thyroid-Associated Ophthalmopathy
Status: UNKNOWN
Conditions: Graves Ophthalmopathy|Graves Disease|Thyroid-associated Ophthalmopathy|Thyroid Diseases|Endocrine System Diseases|Eye Diseases, Hereditary|Hyperthyroidism|Autoimmune Diseases|Immune System Diseases
Interventions: DRUG: Doxycycline hyclate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of THR-1442 Compared to Dapagliflozin as Add-on Therapy to Metformin in T2DM
Status: UNKNOWN
Conditions: T2DM
Interventions: DRUG: THR-1442 and Dapagliflozin placebo|DRUG: Dapagliflozin 10mg and THR1442 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Avutometinib (VS-6766) +Defactinib With Gemcitabine and Nab-paclitaxel in Patients With Pancreatic Cancer
Status: RECRUITING
Conditions: KRAS Activating Mutation|Metastatic Cancer|Pancreas Cancer|Neoplasms Pancreatic|Malignant Neoplasm of Pancreas
Interventions: DRUG: avutometinib (VS-6766) and defactinib in combination with gemcitabine and nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Cyclophosphamide Followed by Vaccine Therapy in Treating Patients With Relapsed Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: KGEL vaccine|BIOLOGICAL: Filgrastim|BIOLOGICAL: Rituximab|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Northwest Coalition for Primary Care Practice Support
Status: COMPLETED
Conditions: Cardiovascular Disease|Essential Hypertension|Nicotine Dependence|Hyperlipidemia
Interventions: OTHER: Coaching|OTHER: Educational Outreach|OTHER: Site Visits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Clinical Study to Evaluate the Long-Term Efficacy and Tolerability of a Daily Anti-Aging Daily Serum
Status: COMPLETED
Conditions: Photoaging|Wrinkle
Interventions: OTHER: Cleansing Lotion|OTHER: Facial Moisturizer|OTHER: Sunscreen SPF 40+
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Transcranial Stimulation and Motor Training in Stroke Rehabilitation
Status: UNKNOWN
Conditions: Stroke|Cerebral Infarction|Cerebrovascular Disorders|Brain Diseases
Interventions: DEVICE: Anodal tDCS|OTHER: Motor Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Long Term Safety and Efficacy of Albiglutide in Combination With Oral Monotherapy Antihyperglycemic Medications in Japanese Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Albiglutide|DRUG: Sulfonylurea|DRUG: Biguanide|DRUG: Glinide|DRUG: Thiazolidinedione|DRUG: Alpha-glucosidase inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azacitidine With Carboplatin and Paclitaxel for Newly Diagnosed Ovarian Cancer
Status: WITHDRAWN
Conditions: Ovarian Cancer
Interventions: DRUG: Azacitidine|DRUG: Azacitidine|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of a New Trans-epithelial Photorefractive Keratectomy (Streamlight PRK) Compared to Conventional PRK Procedures
Status: COMPLETED
Conditions: Myopia ≤ -6 Diopters or Myopic Astigmatism ≤ -4 Diopters
Interventions: PROCEDURE: Photorefractive keratectomy (PRK)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot, Opened, Randomized Clinical Trial to Assess the Efficacy of Duloxetine in the Treatment of Fibromialgy in Patients With Infection by HIV 1+
Status: COMPLETED
Conditions: Fibromyalgia|HIV-1 Infection
Interventions: DRUG: Duloxetine 60 mg, QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercises on Total Body Health in Children With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Bone Density Increased
Interventions: OTHER: Exercise therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety and Tolerability of Cendakimab in Chinese Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Cendakimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Performing Peripheral Pulmonary Lesion Biopsy Using Robotic Bronchoscopy-Guided Cryoprobe
Status: COMPLETED
Conditions: Bronchi--Diseases|Lung Diseases, Obstructive|Lesions Mass
Interventions: DEVICE: Cryoprobe biopsy|PROCEDURE: Forceps biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Micronutrients and Life Skills Education on the Health and Nutrition of Adolescent and Young Women in Pakistan
Status: UNKNOWN
Conditions: Adolescents|Anemia|Pregnancy|Empowerment
Interventions: DIETARY_SUPPLEMENT: Multiple micronutrients (UNIMMAP composition)|BEHAVIORAL: Life skills based education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immunometabolic Mechanisms of Blood Flow Restriction (BFR) Training After Anterior Cruciate Ligament Reconstruction
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: DEVICE: AirBand|DEVICE: uninflated AirBand
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of AVE5026 in the Prevention of Venous Thromboembolism in Cancer Patients Undergoing Chemotherapy
Status: COMPLETED
Conditions: Venous Thromboembolism|Cancer
Interventions: DRUG: Semuloparin sodium|DRUG: Placebo (for semuloparin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High-sensitivity Troponin T in Acute Myocardial Infarction After Cardiac Valvular Surgery
Status: UNKNOWN
Conditions: Acute Myocardial Infarction|Disorder; Heart, Functional, Postoperative, Cardiac Surgery|Myocardial Infarction|Heart Valve Diseases
Interventions: OTHER: Serum levels of high-sensitivity troponin T|OTHER: Twelve-lead ECGs|OTHER: Transthoracic echocardiography (TTE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Signature of the Host Response to a Respiratory Viral Infection, in the Prediction of Bronchiolitis Obliterans
Status: RECRUITING
Conditions: Allogeneic Hematopoietic Stem Cell Recipients|Acute Respiratory Infection|Parainfluenza Virus (PIV)
Interventions: OTHER: samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Physical Exercise in the Quality of Life and Physical Fitness of Elderly Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Physical Activity|Physical Fitness|Quality of Life
Interventions: OTHER: Short intervention protocol|OTHER: Long intervention protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Carboplatin and Paclitaxel With or Without Bevacizumab in Treating Patients With Newly Diagnosed Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cavity Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: carboplatin|DRUG: paclitaxel|OTHER: questionnaire administration|OTHER: study of socioeconomic and demographic variables|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of SEP-363856 in Acutely Psychotic Adults With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: SEP-363856|DRUG: Placebo - Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Controlled Trial of Kangaroo Mother Care in Increasing the Rate of Weight Gain Among Neonates
Status: COMPLETED
Conditions: Low Birth Weight Among Neonates
Interventions: PROCEDURE: Kangaroo Mother Care|PROCEDURE: Conventional Mother Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Proximal Femoral Nail Antirotation (PFNA) Versus PFNA Augmentation
Status: COMPLETED
Conditions: Hip Fractures|Closed Fracture of Hip
Interventions: DEVICE: PFNA Augmentation (Synthes)|DEVICE: PFNA (Synthes)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation to Improve Speech in Aphasia
Status: COMPLETED
Conditions: Aphasia|Cerebrovascular Stroke
Interventions: DEVICE: Transcranial Magnetic Stimulation, Repetitive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Therapy in Cervical Cancer
Status: NOT_YET_RECRUITING
Conditions: Uterine Cervical Neoplasms
Interventions: DRUG: Disitamab Vedotin and Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bidirectional MyoKinetic Implanted Interface for Natural Control of Artificial Limbs
Status: RECRUITING
Conditions: Upper Limb Amputation at the Wrist
Interventions: DEVICE: Magnetic markers implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Pupillometry and Somatosensory Evoked Potential in Cardiac Arrest
Status: UNKNOWN
Conditions: Cardiac Arrest|Cardiopulmonary Arrest With Successful Resuscitation|Resuscitation
Interventions: DIAGNOSTIC_TEST: Somatosensory Evoked Potentials|DIAGNOSTIC_TEST: Automated Pupillometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Cetuximab in Squamous Cell Carcinoma of the Skin Expressing EGFR
Status: COMPLETED
Conditions: Skin Diseases|Carcinoma, Squamous Cell
Interventions: DRUG: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of the COVID-19 (SARS-CoV-2 Disease) on Psychopathology
Status: COMPLETED
Conditions: Psychosis;Schizophrenic|Personality Disorders|Mood Disorders|Anxiety Disorders|Post Traumatic Stress Disorder
Interventions: OTHER: Psychometric scale administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dasatinib in Treating Patients With Locally Advanced or Metastatic Mucosal Melanoma, Acral Melanoma, or Vulvovaginal Melanoma That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: DRUG: dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measuring the Effects of Rhopressa on Episcleral and Retinal Blood Flow in Ocular Hypertension and Glaucoma Suspects
Status: COMPLETED
Conditions: Ocular Hypertension|Suspect Glaucoma
Interventions: DRUG: Netarsudil ophthalmic solution 0.02% one drop nightly for 1-2 weeks
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Optimal Width of Gastric Conduit for Minimally Invasive Esophagectomy: Wide or Narrow?
Status: UNKNOWN
Conditions: Anastomotic Leakage
Interventions: PROCEDURE: Narrowed Gastric Conduit|PROCEDURE: Widened Gastric Conduit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of a Software Application for Patients Hospitalized After Suicidal Ideation or Suicide Attempts
Status: COMPLETED
Conditions: Suicide, Attempted|Suicidal Ideation
Interventions: DEVICE: Software Application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Saccharin and Acesulfame Potassium Consumption and Glucose Homeostasis in Older Adults With Prediabetes
Status: RECRUITING
Conditions: Continuous Glucose Monitoring|Oral Glucose Tolerance|Insulin Sensitivity|Inflammatory Markers
Interventions: OTHER: Non-Nutritive Sweetener Intake and impact on glucose homeostasis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Moxibustion Reduces Symptoms and Improves Quality of Life in Patients With Allergic Rhinitis
Status: RECRUITING
Conditions: Allergic Rhinitis
Interventions: BEHAVIORAL: Ordinary moxibustion volume group|BEHAVIORAL: First group of heavy moxibustion|BEHAVIORAL: Second groups of heavy moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: QYHJ Granules Versus Xeloda in Metastatic Pancreatic Cancer
Status: UNKNOWN
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Xeloda|DRUG: QYHJ Granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Mycoprotein Effect on Glycaemic Control in South Asians
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: Test food containing different types of dietary protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Efficacy of Blue Fenugreek Kale Extract (BFKE) on Skin
Status: COMPLETED
Conditions: Skin Health
Interventions: OTHER: Blue fenugreek kale extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Probiotics on Oral Health
Status: COMPLETED
Conditions: Periodontal Health|Dental Plaque Accumulation
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ear Acupuncture for Acute Sore Throat in Patients Unable to Take Non-steroidal Anti-inflammatory Agents (NSAIDs)
Status: TERMINATED
Conditions: Acute Sore Throat
Interventions: DEVICE: Ear Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Combination of Terbutaline and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia
Status: UNKNOWN
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Terbutaline|DRUG: Danazol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Escalating Single Doses of TAK-137 in Healthy Participants
Status: COMPLETED
Conditions: Dose Finding Study
Interventions: DRUG: TAK-137|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Extension Study of GDC-0853 in Participants With Moderate to Severe Active Systemic Lupus Erythematosus
Status: TERMINATED
Conditions: Lupus Erythematosus, Systemic
Interventions: DRUG: GDC-0853
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ontario ICU Clinical Best Practices Demonstration Project
Status: COMPLETED
Conditions: Ventilator Acquired Pneumonia|Catheter Related Blood Stream Infections|Pressure Ulcer Prophylaxis|DVT Prophylaxis|Restrictive Blood Transfusion Strategy|Daily Spontaeous Breathing Trials
Interventions: BEHAVIORAL: Focused knowledge translation strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: ECT
Clinical trial: Effect of Three Silicon Based Food Supplements on the Urinary Excretion of Aluminum and Other Metals (SILIAL)
Status: COMPLETED
Conditions: Aluminium Overload|Biological Availability
Interventions: DIETARY_SUPPLEMENT: ORGONO Living Silica Acacia Gum-MMST Powder|DIETARY_SUPPLEMENT: ORGONO Living Silica Malto-OSA Powder|DIETARY_SUPPLEMENT: ORGONO Living Silica Collagen Booster|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: DANish DELIrium Study On Neurointensive Care Patients
Status: COMPLETED
Conditions: Acquired Brain Injuries|Delirium|Acute Brain Injury
Interventions: OTHER: intervention bundle (sedation, pain, mobilization and sleep)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intrathecal Morphine Compared to Conventional Medical Management for Pain Control and Opioid-related Side Effects
Status: TERMINATED
Conditions: Chronic Pain
Interventions: DEVICE: SynchroMed Infusion System and Intrathecal Morphine Sulfate|OTHER: Conventional Medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selinexor、Venetoclax and Azactidine in the Treatment of ND AML Patients Who Are Not Eligible for Intense Chemotherapy
Status: RECRUITING
Conditions: Acute Myeloid Leukemia, Adult
Interventions: DRUG: Selinexor|DRUG: Venetoclax|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Newly Diagnosed Mature B-ALL, Burkitt's Lymphoma and Other High-grade Lymphoma in Adults
Status: COMPLETED
Conditions: Burkitt's Lymphoma|Burkitt's Leukemia|Mediastinal Neoplasms|Lymphoblastic Lymphoma|Large Cell Anaplastic Lymphoma
Interventions: DRUG: Adriamycin|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Dexamethasone/Prednisolone|DRUG: VP16|DRUG: Ifosfamide|DRUG: Methotrexate|DRUG: G-CSF|DRUG: Rituximab|DRUG: Vincristine/Vindesine|PROCEDURE: Irradiation (in specific conditions)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Benefits of NIRAF Detection for Identifying Parathyroid Glands During Total Thyroidectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Postoperative Hypoparathyroidism|Thyroid Disease|Thyroid Neoplasms|Thyroid Cancer
Interventions: DEVICE: NIRAF Detection Technology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Allogeneic Hematopoietic Stem Cell Transplantation for High-Risk Hematologic Malignancies Using One Haploidentical Donor
Status: COMPLETED
Conditions: Hematopoietic/Lymphoid Cancer
Interventions: RADIATION: Total-Body Irradiation (TBI)|BIOLOGICAL: Donor Lymphocyte Infusion (DLI)|DRUG: Cyclophosphamide|PROCEDURE: Allogeneic hematopoietic stem cell transplantation (HSCT)|DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT