pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clinical Study Evaluating Safety and Efficacy of Fluticasone Furoate and Fluticasone Propionate in People With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone furoate 50mcg|DRUG: Fluticasone propionate 100mcg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: β-alanine Supplementation in Adults With Overweight/Obesity
Status: COMPLETED
Conditions: Prediabetes|Hyperglycemia|Overweight or Obesity
Interventions: DIETARY_SUPPLEMENT: Beta-alanine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase 1/2 Study of Vascular Disrupting Agent NPI-2358 + Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: docetaxel|DRUG: NPI-2358 + docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nondependent Lung Ventilation and Fluid Responsiveness
Status: UNKNOWN
Conditions: Lung Disease|Undergoing Thoracosocpic Surgery
Interventions: PROCEDURE: High Frequency Positive Pressure Ventilation|PROCEDURE: Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Education Regarding Living Donor Transplant Among Kidney Transplant Candidates
Status: COMPLETED
Conditions: Kidney Transplant|Living-Donor Kidney Transplant|Chronic Kidney Disease|End-stage Renal Disease
Interventions: BEHAVIORAL: Intensive initial education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Association Between Conditioned Pain Modulation and Pain Catastrophizing in Chronic Low Back Pain
Status: COMPLETED
Conditions: Catastrophizing Pain|Pain, Somatic|Chronic Low Back Pain
Interventions: DIAGNOSTIC_TEST: PPT measurement|DIAGNOSTIC_TEST: Pain catastrophizing scale|PROCEDURE: Cold Pressor Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Defining Neurobiological Links Between Substance Use and Mental Illness
Status: RECRUITING
Conditions: Major Depressive Disorder|Substance Use Disorder|Normal Physiology
Interventions: OTHER: Placebo Nicotine Patch|DRUG: Nicotine Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Influence of IQPAS-119 on Post-Marathon Susceptibility to Infections and Others
Status: COMPLETED
Conditions: Upper Respiratory Tract Symptoms
Interventions: DIETARY_SUPPLEMENT: IQP-AS-119|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Progesterone Rise in Agonist Versus Antagonist in Vitro Fertilization (IVF) Cycles
Status: UNKNOWN
Conditions: Pregnancy Outcome After In Vitro Fertilization (IVF)
Interventions: OTHER: In vitro fertilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Hemostatic and Hemodynamic Effects of Adrenaline During Endoscopic Sinus Surgery
Status: UNKNOWN
Conditions: Chronic Sinusitis
Interventions: DRUG: 1% lidocaine with 1:100,000 adrenaline|DRUG: 1% lidocaine with 1:200,000 adrenaline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effect of Tacrosolv in Patients With Allergic Rhinoconjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis|Allergic Rhinitis
Interventions: DRUG: Eye Drops, Solution in Single-Dose Container
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postural and Anthropometric Properties of Foot and Ankle of Patients With DMD
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy|Ambulation Difficulty|Posture Disorders in Children|Ambulation Disorder, Neurologic
Interventions: OTHER: foot posture index, north star ambulation assessment, timed performance tests, 6 minute walk test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ologen (OculusGen)-Glaucoma MMC Control in Pakistan
Status: COMPLETED
Conditions: Glaucoma|Trabeculectomy
Interventions: DEVICE: ologen collagen matrix in glaucoma filtering surgery|DRUG: MMC in glaucoma filtering surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of 177Lu-FAP-2286 in Advanced Solid Tumors (LuMIERE)
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: 68Ga-FAP-2286|DRUG: 177Lu-FAP-2286
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Inhalation Therapy on Children's Fear and Anxiety Levels and Physiological Parameters
Status: RECRUITING
Conditions: Anxiety and Fear
Interventions: BEHAVIORAL: Fish-shaped nebulizer and fish-shaped toy|DEVICE: Silent nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Onvansertib in Combination With FOLFIRI and Bevacizumab for Second Line Treatment of Metastatic Colorectal Cancer Patients With a Kras Mutation
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer|KRAS Gene Mutation
Interventions: DRUG: Onvansertib|BIOLOGICAL: Bevacizumab|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MabThera/Rituxan (Rituximab) Alone and in Combination With Roferon-A in Patients With Follicular or Other CD20+ Low-Grade (Indolent) Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: rituximab|DRUG: interferon-a-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systemic Cross-talk Between Brain, Gut, and Peripheral Tissues in Glucose Homeostasis: Effects of Exercise Training
Status: COMPLETED
Conditions: Obesity|Insulin Resistance|Type2 Diabetes|Exercise Training
Interventions: BEHAVIORAL: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment of REfractory Overactive BLadder With the AXonics Sacral Neuromodulation System (RELAX-OAB)
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DEVICE: Axonics Sacral Neuromodulation (SNM) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Breathing Exercise With Pinwheel on the Quality of Life in Children With Cystic Fibrosis Disease
Status: COMPLETED
Conditions: Nursing Caries|Breathing Exercise
Interventions: DEVICE: Pinwheel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Effectiviness of Two Different Bupivacaine Concentrations of the Pericapsular Nerve Group (PENG) Block
Status: RECRUITING
Conditions: Hip Fractures|Postoperative Pain
Interventions: PROCEDURE: Pericapsular nerve group block 0,25%|PROCEDURE: Pericapsular nerve group block 0,16%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Sublingual Immunotherapy in Children Allergic to House Dust Mites
Status: UNKNOWN
Conditions: Bronchial Asthma|Allergic Rhinitis
Interventions: DRUG: sublingual house dust mites allergen extract|DRUG: placebo in sublingual applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel in Hormone Refractory Prostate Cancer (HRPC)[Weekly or 3weekly TAX + Prednisone in HRPC]
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy, Rituximab, and Ixazomib Citrate in Treating Patients With Non-Hodgkin Lymphoma
Status: UNKNOWN
Conditions: Adult Burkitt Lymphoma|B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Burkitt Lymphoma|Diffuse Large B-Cell Lymphoma|MYC Gene Mutation|Plasmablastic Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide|DRUG: Ixazomib Citrate|OTHER: Laboratory Biomarker Analysis|DRUG: Methotrexate|DRUG: Prednisone|BIOLOGICAL: Rituximab|DRUG: Therapeutic Hydrocortisone|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FOLFOX Chemotherapy Regimen (5-FU, Leucovorin, Oxaliplatin) in Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: 5-FU|DRUG: Cetuximab|DRUG: Dasatinib|DRUG: Leucovorin|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Preschool Outcomes by Addressing Maternal Depression in Head Start
Status: RECRUITING
Conditions: Maternal Depression
Interventions: BEHAVIORAL: Problem-solving education (PSE)|BEHAVIORAL: Engagement sessions|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cytokine Inhibition in Chronic Fatigue Syndrome Patients
Status: COMPLETED
Conditions: Chronic Fatigue Syndrome
Interventions: DRUG: Anakinra|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Kneehab in Strengthening Quadriceps in Rehabilitation Post Anterior Cruciate Ligament (ACL) Reconstruction
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: DEVICE: Kneehab|DEVICE: Poli-Stim|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aminosalicylic Acid Withdrawal Study in Long Standing Inactive Ulcerative Colitis
Status: COMPLETED
Conditions: Colitis, Ulcerative|Aminosalicylic Acid
Interventions: DRUG: Mesalazine|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Peri-implantitis and Peri-implant Mucositis
Status: RECRUITING
Conditions: Atherosclerosis|Endothelial Dysfunction|Peri-Implantitis|Peri-implant Mucositis
Interventions: PROCEDURE: Non-surgical periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Teen Video Study to Reduce Risky Driving and Sexual Behavior in Adolescents
Status: COMPLETED
Conditions: Pregnancy|Sexually Transmitted Infections|Automobile Accidents
Interventions: BEHAVIORAL: Seventeen Days|BEHAVIORAL: Driving Skills for Life
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Femoral and Obturatory Nerve Joint Branches Conventional Radiofrequency Thermocoagulation ,Intraarticular Steroid Injection and Pericapsular Nerve Group (PENG) Block in Chronic Hip Pain
Status: RECRUITING
Conditions: Chronic Hip Pain
Interventions: PROCEDURE: radiofrequency thermocoagulation to the articular branches of the femoral and obturatory nerves|PROCEDURE: intraairticular steroid injection|PROCEDURE: pericapsular nerve group (PENG) block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MAAS Method (Minimal-flow Auto-control Anesthesia System) for the Administration of Desflurane and Sevoflurane
Status: RECRUITING
Conditions: Anesthesia|Sevoflurane|Desflurane|Low Flow Anesthesia
Interventions: PROCEDURE: Sevoflurane uptake and supply|PROCEDURE: Washout phase|PROCEDURE: Desflurane uptake and supply|PROCEDURE: Final phase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Outcomes of Virtual Reality Based Serious Gaming and Lecture Based Training for Advanced Life Support
Status: COMPLETED
Conditions: Advanced Cardiac Life Support
Interventions: OTHER: ALS VR (VR based serious gaming module for advanced life support training)|OTHER: Lecture based training for advanced life support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Brainwave Entrainment During Emergence
Status: NOT_YET_RECRUITING
Conditions: Anesthesia, General
Interventions: OTHER: Binaural sound|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Relative Bioavailability Study of Nirmatrelvir/Ritonavir 4 Different Fixed Dose Combination Tablets Relative to the Commercial Tablets in Healthy Participants
Status: COMPLETED
Conditions: Biological Availability|Healthy Participants
Interventions: DRUG: Nirmatrelvir/ ritonavir|DRUG: Nirmatrelvir/ritonavir|DRUG: Nirmatrelvir/ritonavir|DRUG: Nirmatrelvir/ ritonavir|DRUG: Nirmatrelvir/ ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: PREVENTION OF PERINATAL DEPRESSION BY EPDS DURING THE FIRST PRENATAL CONSULTATION AT MATERNITY DEPARTMENT
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripartum Depression (PPD)
Interventions: DIAGNOSTIC_TEST: The Edinburgh Postnatal Depression Scale (EPDS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: HMB and Exercise-induced Muscle Damage
Status: RECRUITING
Conditions: Supplementation|Sport|Sports Nutrition|Muscle Damage|Recovery
Interventions: DIETARY_SUPPLEMENT: HMB supplementation|DIETARY_SUPPLEMENT: Placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ability of Caregivers to Provide Ventilation With the SAVe Resuscitator in a Model
Status: COMPLETED
Conditions: Pre-hospital Ventilation
Interventions: PROCEDURE: Hold mask|PROCEDURE: Strap Mask|PROCEDURE: Airway
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IMPase in Treatment-resistant Depression
Status: RECRUITING
Conditions: Depressive Disorder, Treatment-Resistant
Interventions: DRUG: Ebselen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Stress Doses of Hydrocortisone on Coagulation Dysfunction in Patients With Septic Shock
Status: COMPLETED
Conditions: Coagulation Dysfunction in Septic Shock|Hemodynamic Improvement Induced by Hydrocortisone
Interventions: DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study of Cyclophosphamide Treatment for Idiopathic Retroperitoneal Fibrosis
Status: UNKNOWN
Conditions: Idiopathic Retroperitoneal Fibrosis
Interventions: DRUG: Cyclophosphamide and glucocorticoids|DRUG: Glucocorticoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pain Regression in Patients With Myofascial Facial Pain Using Dextrose, Local Anaesthesia and Saline.
Status: UNKNOWN
Conditions: Myofascial Pain Syndrome
Interventions: OTHER: Dextrose Prolotherapy|OTHER: Local Anaesthesia|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination OZURDEX® & EyLea® vs. OZURDEX® Monotherapy in IncompLete-Responders wIth Diabetic Macular Edema
Status: WITHDRAWN
Conditions: Diabetic Macular Edema
Interventions: DRUG: OZURDEX|BIOLOGICAL: Eylea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Syncope Trial to Understand Tilt Testing or ECG Recording Tenth Prevention of Syncope Trial
Status: RECRUITING
Conditions: Syncope
Interventions: DIAGNOSTIC_TEST: Diagnostic Test: Head Up Tilt Table (HUT)|DEVICE: Device: Implantable Loop Recorder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of Mindful Exercise on Back Pain in Older Patients With Primary Osteoporosis
Status: RECRUITING
Conditions: Older People|Primary Osteoporosis|Back Pain
Interventions: OTHER: Mindful exercise|OTHER: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety, Tolerability and Efficacy of R2R01 Combined With SOC as Compared to SOC Alone in Outpatients With Worsening Heart Failure (WHF)
Status: RECRUITING
Conditions: Heart Failure|Worsening Heart Failure (WHF)
Interventions: DRUG: Placebo|DRUG: R2R01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Retrospective Analysis of the Effects of Perioperative Osteoanabolic Treatment on Patients With Spinal (Fusion) Surgery.
Status: COMPLETED
Conditions: Spinal (Fusion) Surgery
Interventions: OTHER: Data collection (Laboratory tests, Radiologic diagnostics, Patient data taken from existing medical charts)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact on the Time to Diagnosis of Serious Postoperative Complications by a Controlled Connected Medical Device
Status: UNKNOWN
Conditions: Medical Device
Interventions: DEVICE: Active "SMART ANGEL" solution|DEVICE: Inactive "SMART ANGEL" solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Improving Pancreatic Cancer Care by the Use of Computational Science and Technology
Status: RECRUITING
Conditions: Pancreatic Cancer|Pancreatic Cyst|Pancreatic Adenocarcinoma|Pancreatic Diseases|Pancreas Adenocarcinoma|Pancreas Cyst
Interventions: OTHER: No interventions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Pneumococcal Vaccine Schedules in Ho Chi Minh City, Vietnam
Status: COMPLETED
Conditions: Pneumococcal Vaccines
Interventions: BIOLOGICAL: PCV10|BIOLOGICAL: PCV13
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Photosensitivity Proof of Concept Trial
Status: COMPLETED
Conditions: Photosensitive Epilepsy
Interventions: DRUG: carbamazepine 400mg|DRUG: levetiracetam 1000mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Uterine Artery Embolization With Microspheres in Patients With Leiomyoma.
Status: COMPLETED
Conditions: Uterine Leiomyoma
Interventions: DEVICE: Uterine Embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ThiPhiSA: New Pathways to Prevention From Community TB Screening in South Africa
Status: RECRUITING
Conditions: Tuberculosis|HIV I Infection
Interventions: OTHER: Community-delivered TB preventive therapy (TPT) - 3 months weekly isoniazid plus rifapentine (3HP)|OTHER: Clinic-link TPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nutritional Intervention for Children With ASD and/or ADHD
Status: COMPLETED
Conditions: ADHD|ASD|Probiotics|Microbiota
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II/III Study of SEP-190 (Eszopiclone) in Patients With Primary Insomnia (Study 190-126)
Status: COMPLETED
Conditions: Primary Insomnia
Interventions: DRUG: Eszopiclone 1 mg|DRUG: Eszopiclone 2 mg|DRUG: Eszopiclone 3 mg|DRUG: Placebo|DRUG: Zolpidem Tartrate 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Automatic Defibrillator Implantation Trial - Reduce Inappropriate Therapy
Status: COMPLETED
Conditions: Primary Prevention of Sudden Cardiac Arrest
Interventions: DEVICE: Standard ICD programming|DEVICE: High rate cutoff|DEVICE: Long delay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Creon® on Pancreatic Exocrine Insufficiency in Subjects With Diabetes Mellitus Type 2
Status: WITHDRAWN
Conditions: Exocrine Pancreatic Insufficiency in Subjects With Diabetes Mellitus Type 2
Interventions: DRUG: Creon|DRUG: Creon 25000 matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Study to Evaluate the Effect of Treatment With Fentanyl Buccal Tablets on Pain Anxiety Symptoms When Used for the Management of Breakthrough Pain
Status: TERMINATED
Conditions: Pain|Chronic Pain|Breakthrough Pain
Interventions: DRUG: Fentanyl Buccal Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Output Changes in Cesarean Section
Status: UNKNOWN
Conditions: Cardiac Output,Low|Hemodynamic Instability|Obstetrical Complication of Anesthesia
Interventions: DRUG: Norepinephrine|DRUG: Phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Whole Body Vibration in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: OTHER: whole body vibration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Binge Eating in Obese Patients in Primary Care
Status: COMPLETED
Conditions: Obesity|Binge Eating
Interventions: DRUG: Sibutramine|DRUG: Placebo|BEHAVIORAL: Self-help CBT + Sibutramine|BEHAVIORAL: Self-help CBT + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction (DDI) Study to Assess ODM-201 as a Victim of CYP3A4 Inhibition or Induction
Status: COMPLETED
Conditions: Biological Availability
Interventions: DRUG: BAY1841788 (ODM-201)|DRUG: Itraconazole|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: "In Vivo" Comparison in Human Carotid Atherosclerosis: Plaque Neovascularization
Status: COMPLETED
Conditions: Carotid Artery Disease|Plaque Neovascularization
Interventions: OTHER: Contrast enhanced ultrasound of the carotid plaque|OTHER: Dynamic contrast-enhanced carotid plaque MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Robotic Versus Laparoscopic Techniques for Revisional Bariatric Surgery
Status: NOT_YET_RECRUITING
Conditions: Bariatric Surgery|Robotic Surgery
Interventions: PROCEDURE: Robotic bariatric surgery - revisional|PROCEDURE: Laparoscopic bariatric surgery - revisional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Citrate Pharmacokinetics in Critically Ill Liver Failure Patients Receiving CRRT
Status: COMPLETED
Conditions: Citrate Toxicity|Regional Citrate Anticoagulation|Liver Failure, Acute|Liver Failure, Acute on Chronic|Pharmacokinetic|Continuous Renal Replacement Therapy
Interventions: DIAGNOSTIC_TEST: Pharmacokinetic study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hydratation Status at Initiation of Peritoneal Dialysis: Study of the Role of Peritoneal Permeability
Status: UNKNOWN
Conditions: Fluid Overload|Peritoneal Hyperpermeability|Peritoneal Dialysis|Chronic Kidney Disease
Interventions: BIOLOGICAL: modified Peritoneal Equilibration test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A 10-Week, Open-Label, Flexible Dose Adaptive Study Evaluating the Efficacy of Vortioxetine in Subjects With Panic Disorder
Status: COMPLETED
Conditions: Panic Disorder
Interventions: DRUG: Vortioxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PIPAC Nab-pac for Stomach, Pancreas, Breast and Ovarian Cancer
Status: COMPLETED
Conditions: Peritoneal Carcinomatosis|Ovarian Cancer Stage IIIB|Ovarian Cancer Stage IIIC|Ovarian Cancer Stage IV|Breast Cancer Stage IIIB|Breast Cancer Stage IIIc|Breast Cancer Stage IV|Stomach Cancer Stage III|Stomach Cancer Stage IV With Metastases|Pancreas Cancer, Stage III|Pancreas Cancer, Stage IV
Interventions: DRUG: PIPAC with Abraxane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Whey Protein Intervention on Body Composition and Muscle Function in the Elderly With Sacropenia
Status: UNKNOWN
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: protein supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Surgery and Oxaliplatin or Mitomycin C in Treating Patients With Tumors of the Appendix
Status: COMPLETED
Conditions: Carcinoma of the Appendix|Primary Peritoneal Cavity Cancer
Interventions: DRUG: mitomycin C|DRUG: oxaliplatin|PROCEDURE: therapeutic conventional surgery|OTHER: quality-of-life assessment|DRUG: hyperthermic intraperitoneal chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Curve Progression and the Need for Bracing in Adolescent Idiopathic Scoliosis With Calcium + Vitamin D Supplementation
Status: RECRUITING
Conditions: Scoliosis|Spinal Curvatures|Spinal Diseases|Bone Health|Vitamin D
Interventions: DIETARY_SUPPLEMENT: Ca500mg|DIETARY_SUPPLEMENT: VitD800IU|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Turmeric Extract in Patients With Arthrosis.
Status: COMPLETED
Conditions: Arthralgia|Stiffness of Unspecified Joint, Not Elsewhere Classified|Disturbance of Activity and Attention|Quality of Life
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Turmeric
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Cognitive-Behavioral Therapy For Obsessive-Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder (OCD)
Interventions: BEHAVIORAL: Intensive Cognitive Behavioral Therapy (CBT)|BEHAVIORAL: Waitlist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Luteinizing Hormone (LH) Supplementation Following Gonadotropin-releasing Hormone (GnRH) Antagonist Administration in Advanced Reproductive Ageing Women Undergoing IVF and Embryo Transfer (IVF/ET)
Status: COMPLETED
Conditions: Pregnancy Result Rape
Interventions: DRUG: Leuveris|DRUG: Leuveris
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotic Supplement in Alleviating Functional Gastrointestinal Symptoms
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Probiotic (Active high)|DIETARY_SUPPLEMENT: Probiotic (Active low)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mental Practice and Therapeutic Exercise in Young Nulliparous Women
Status: RECRUITING
Conditions: Therapeutic Exercise|Motor Imagery|Action Observation
Interventions: BEHAVIORAL: Motor Imagery plus therapeutic exercise|BEHAVIORAL: Action observation plus therapeutic exercise|BEHAVIORAL: Sham action observation plus therapeutic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Phase II Trial of ZD1839 (IRESSA) in Patients With Malignant Mesothelioma
Status: COMPLETED
Conditions: Mesothelioma
Interventions: DRUG: ZD1839
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Bazedoxifene/Conjugated Estrogens Combinations In Postmenopausal Women
Status: COMPLETED
Conditions: Endometrial Hyperplasia|Osteoporosis
Interventions: DRUG: Bazedoxifene/Conjugated Estrogen|DRUG: Bazedoxifene/Conjugated Estrogen|DRUG: CE 0.45 mg/MPA 1.5mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Citrate Versus Heparin in Continuous Renal Replacement Therapy :
Status: COMPLETED
Conditions: Acute Kidney Injury|Citrate|Cytokines|Hemodynamic Responses
Interventions: PROCEDURE: Regional citrate anticoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study Of Sunitinib In Combination With Folfox In Patients With Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: sunitinib + mFOLFOX6|DRUG: sunitinib + mFOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Developmental Effects of NICU Positioning
Status: COMPLETED
Conditions: Premature Birth of Newborn
Interventions: DEVICE: Dandle Roo/Dandle Wrap|OTHER: Traditional NICU Positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Study on the Metoprolol Optimal Dosing Pathway of Metoprolol Application in Chinese Patients With Acute Coronary Syndrome
Status: UNKNOWN
Conditions: ACS - Acute Coronary Syndrome
Interventions: DRUG: Metoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ambulatory Surgery After Hepatectomy: Monitoring by Domomedicine Connected Tools and a Dedicated Nurse.
Status: NOT_YET_RECRUITING
Conditions: Liver Tumor|Hepatectomy
Interventions: OTHER: Domomedicine and dedicated nursing care for a close and secure monitoring after an ambulatory hepatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effectiveness of Bilateral Ultrasound-Guided Erector Spinae Plane Block
Status: COMPLETED
Conditions: Erector Spinae Plane Block
Interventions: DRUG: Bilateral Ultrasound-Guided Erector Spinae Plane Block|DRUG: Morphine Consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Autologous T-Cells Expressing a Second Generation CAR for Treatment of T-Cell Malignancies Expressing CD5 Antigen
Status: RECRUITING
Conditions: T-cell Acute Lymphoblastic Lymphoma|T-non-Hodgkin Lymphoma|T-cell Acute Lymphoblastic Leukemia
Interventions: GENETIC: Autologous CD5.CAR/28zeta CAR T cells|GENETIC: Allogeneic CD5.CAR/28zeta CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Glycaemic Fluctuation and Oxidative Stress Between Two Short-term Therapies for Type 2 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: insulin lispro|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bupivacaine Liposome Plus Bupivacaine or Ropivacaine for Pericapsular Nerve Group Block in Hip Arthroplasty (PENG)
Status: NOT_YET_RECRUITING
Conditions: Femoral Neck Fractures|Femur Head Necrosis|Hip Fractures
Interventions: DRUG: Liposomal bupivacaine plus bupivacaine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hormonal Ablation, Imatinib Mesylate and Docetaxel for Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Docetaxel|DRUG: Imatinib Mesylate|DRUG: Leuprolide|DRUG: Goserelin Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oral Administration of 9-cis β Carotene Rich Powder of the Alga Dunaliella Bardawil
Status: ACTIVE_NOT_RECRUITING
Conditions: Retinitis Pigmentosa
Interventions: DIETARY_SUPPLEMENT: Alga Dunaliella Bardawil|OTHER: Placebo (starch)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chorioamnionitis: Observation of at Risk Infants vs Standard Care
Status: WITHDRAWN
Conditions: Chorioamnionitis|Early Onset Neonatal Sepsis|Sepsis of the Newborn
Interventions: OTHER: Clinical observation|OTHER: Standard management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Research of the Key Technology and Standardization of Minimal Invasive Treatment for Hepatolithiasis
Status: UNKNOWN
Conditions: Biliary Stones
Interventions: PROCEDURE: Laparoscopic operation|PROCEDURE: Open operation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telephone Counseling: Men With Prostate Cancer & Partners
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Telephone Interpersonal Counseling|BEHAVIORAL: Telephone delivered education only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of Aspiration Risk Assessment in Stroke Units
Status: TERMINATED
Conditions: Stroke, Acute
Interventions: DIAGNOSTIC_TEST: Daniels Water Swallow Test|DIAGNOSTIC_TEST: Flexible Endoscopic Evaluation of Swallowing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Phase I Study of Cell Therapies for the Treatment of Patients With Relapsed or Refractory AML or High-risk MDS
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: SPRX002|BIOLOGICAL: ARC-T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Alpelisb and Tucatinib in Patients With PIK3CA-Mutant HER2+ Metastatic Breast Cancer.
Status: RECRUITING
Conditions: HER2-positive Metastatic Breast Cancer
Interventions: DRUG: Alpelisib|DRUG: Tucatinib|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells in the Treatment of Subjects With Advance Chronic Obstructive Pulmonary Disease (COPD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BIOLOGICAL: Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tibial Tunnel Placement for ACL Reconstruction
Status: UNKNOWN
Conditions: Complete Tear, Knee, Anterior Cruciate Ligament|Rupture of Anterior Cruciate Ligament
Interventions: PROCEDURE: ACL Reconstruction: Anterior Tunnel|PROCEDURE: ACL Reconstruction: Posterior Tunnel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electrolyte Balance Effects of Sterofundin Versus Normal Saline in Diabetic Ketoacidosis
Status: RECRUITING
Conditions: Treatment Diabetic Ketoacidosis, Electrolyte Balance Effects
Interventions: OTHER: Sterofundin fluid therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Efficacy of the LYMPHA in the Prevention of Lymphedema Following Axillary Dissection for Breast Cancer
Status: UNKNOWN
Conditions: Lymphedema, Breast Cancer
Interventions: PROCEDURE: LYMPHA(LYmphatic Microsurgical Preventive Healing Approach) technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Oral Probiotics on Oral Homeostasis
Status: COMPLETED
Conditions: Gingivitis
Interventions: DIETARY_SUPPLEMENT: Probiotic tablet|DIETARY_SUPPLEMENT: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pioglitazone on Pancreatic Steatosis and Bone Health
Status: COMPLETED
Conditions: Obesity|Type 2 Diabetes
Interventions: DRUG: pioglitazone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ticagrelor Versus Clopidogrel in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type-2 Diabetes Mellitus|Coronary Artery Disease
Interventions: DRUG: Ticagrelor + Aspirin|DRUG: Clopidogrel + Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life Assessment in Daily Clinical Oncology Practice for Patients With Advanced Renal Cell Carcinoma
Status: UNKNOWN
Conditions: Renal Carcinoma Metastatic|Kidney Neoplasms|Renal Cancer
Interventions: OTHER: Electronic PRO in daily clinical practice
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: COLUMBIA-1: Novel Oncology Therapies in Combination With Chemotherapy and Bevacizumab as First- Line Therapy in MSS-CRC
Status: TERMINATED
Conditions: Metastatic Microsatellite-stable Colorectal Cancer
Interventions: DRUG: Durvalumab|DRUG: Oleclumab|DRUG: FOLFOX|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effectiveness of Dry Needling and Ischemic Compression on Tension Type Headache
Status: COMPLETED
Conditions: Tension-Type Headache
Interventions: OTHER: Dry Needling and Ischemic Compression Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Videocapsule Endoscopy in Lynch Syndrome
Status: RECRUITING
Conditions: Lynch Syndrome|Lynch Syndrome I|Lynch Syndrome II|MLH1 Gene Mutation|MSH2 Gene Mutation|MSH6 Gene Mutation|PMS2 Gene Mutation|Small Bowel Adenocarcinoma
Interventions: DEVICE: Video capsule endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Role of Hypertonic Saline Versus Mannitol in the Management of Raised Intracranial Pressure in Patients With ALF
Status: COMPLETED
Conditions: Acute Liver Failure
Interventions: DRUG: Mannitol|DRUG: 3% hypertonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lesion Dosimetry With 124-Iodine in Metastatic Thyroid Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Thyroid Cancer
Interventions: RADIATION: 131 I-iodine (131-I), 124 I-iodine (124-I)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide-Bortezomib-Dexamethasone (CyBorD) With Daratumumab (DARA)
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Cyclophosphamide|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Laparoscopic Sleeve Gastrectomy Lead to Barrett's Esophagus, 5-year Esophagogastroduodenoscopy Findings: A Retrospective Cohort Study
Status: COMPLETED
Conditions: Barrett Esophagus
Interventions: DIAGNOSTIC_TEST: Laparoscopic Sleeve Gastrectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Postoperative CCRT Followed by Immunotherapy in High-Risk LA HNSCC
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Anti-PD-1 monoclonal antibody|OTHER: Postoperative CCRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Study To Evaluate The Efficacy And Safety Of PH-797804 In Adults With Moderate To Severe Chronic Obstructive Pulmonary Disease (COPD).
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: PH-797804|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Botox as a Treatment for Interstitial Cystitis in Women
Status: COMPLETED
Conditions: Painful Bladder Syndrome|Interstitial Cystitis
Interventions: DRUG: Botox|OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Using Fecal Microbiota Transplants in Anorexia Nervosa
Status: RECRUITING
Conditions: Anorexia Nervosa|Microbiome Dysbiosis
Interventions: BIOLOGICAL: Fecal Microbiome Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sleep and Nocturnal Melatonin in Adults With Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DEVICE: One-night polysomnographic recordings
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer
Status: RECRUITING
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Ifinatamab deruxtecan|DRUG: Topotecan|DRUG: Amrubicin|DRUG: Lurbinectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT