pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study to Evaluate the Efficacy and Safety of CKD-352
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: CKD-352|DRUG: Diquafosol Sodium 3%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Neuroimaging of Postural Reconstruction
Status: COMPLETED
Conditions: Healthy
Interventions: RADIATION: SPECT : ECD-Tc99m - Neurolite, Bristol-Myers Squibb Medical Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of Corifolitropin Alfa in Oocyte Donors
Status: UNKNOWN
Conditions: Female Reproductive Problem|Infertility
Interventions: DRUG: Corifollitropin alfa|DRUG: Recombinant FSH|DRUG: HP-hMG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Effective Mydriasis in Premature Infants
Status: COMPLETED
Conditions: Retinopathy of Prematurity (ROP)
Interventions: DRUG: 1% phenylephrine and 0.2% cyclopentolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study in Subjects With Small Primary Choroidal Melanoma
Status: COMPLETED
Conditions: Uveal Melanoma|Ocular Melanoma|Choroidal Melanoma
Interventions: DRUG: Light-activated AU-011|DEVICE: Laser Activation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Melphalan Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients
Status: COMPLETED
Conditions: Hematologic Malignancies|Nonmalignant Diseases|Immunodeficiencies|Hemoglobinopathies|Genetic Inborn Errors of Metabolism|Fanconi's Anemia|Thalassemia|Sickle Cell Disease
Interventions: DRUG: Melphalan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact of Early Pulmonary Rehabilitation on Multidimensional Aspect of Dyspnea in COPD Patients After Exacerbation
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacological Profile of Different Quercetin Formulations
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DIETARY_SUPPLEMENT: Quercetin LipoMicel (250 mg)|DIETARY_SUPPLEMENT: Quercetin LipoMicel (500 mg)|DIETARY_SUPPLEMENT: Quercetin LipoMicel (1000 mg)|DIETARY_SUPPLEMENT: Regular/standard Quercetin (500 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening, Brief Intervention, and Referral to Treatment for Drug Use
Status: COMPLETED
Conditions: Drug Abuse
Interventions: BEHAVIORAL: Screening/motivational drug intervention|BEHAVIORAL: Motivational placebo intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Growth Charts and Nutritional Supplements on Child Growth in Zambia
Status: COMPLETED
Conditions: Stunting
Interventions: DIETARY_SUPPLEMENT: Lipid based nutrient Supplements (LNS):|DEVICE: Growth Charts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Feasibility and Effect of Resistance Training and Protein Supplementation in Patients With Advanced Gastroesophageal Cancer
Status: RECRUITING
Conditions: Gastro-esophageal Cancer
Interventions: BEHAVIORAL: Resistance training|DIETARY_SUPPLEMENT: Protein supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Health Promotion Comprehensive Education Intervention on the Frailty Levels of Elderly Family Caregivers
Status: COMPLETED
Conditions: Frailty|Caregiver Burden|Frail Elderly Syndrome
Interventions: OTHER: training intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Medial Collateral Ligament Reconstruction With Anteromedial Reinforcement for Medial and Anteromedial Rotatory Knee Instability
Status: RECRUITING
Conditions: Collateral Ligament, Knee; Sprain (Strain), Medial|Anterior Cruciate Ligament Injuries
Interventions: PROCEDURE: Medial Collateral Ligament Reconstruction With Anteromedial Reinforcement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ixiaro as Booster After Mouse-brain Derived Vaccines for Japanese Encephalitis
Status: COMPLETED
Conditions: Japanese Encephalitis
Interventions: BIOLOGICAL: Mouse brain derived japanese encephalitis vaccine (MB-JEV)|BIOLOGICAL: Primary and booster immunizations with MB-JEV|BIOLOGICAL: C) primary immunizations with Ixiaro|BIOLOGICAL: S) Ixiaro booster to MBJEV primed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Preemptive Pharmacogenetic-guided Metoprolol Management for PostoperativeAtrial Fibrillation in Cardiac Surgery
Status: COMPLETED
Conditions: Post-operative Atrial Fibrillation
Interventions: OTHER: Guided Metoprolol Management
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intermittent Fasting on Acute Subconcussive Head Impacts
Status: COMPLETED
Conditions: Sports Injury|Intermittent Fasting
Interventions: OTHER: Soccer Heading|OTHER: Intermittent Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: 64Cu-SAR-bisPSMA for Identification of Participants With Recurrence of Prostate Cancer (COBRA)
Status: COMPLETED
Conditions: Biochemical Recurrence of Malignant Neoplasm of Prostate
Interventions: DRUG: 64Cu-SAR-bisPSMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison Between the Imaging Consent Form and the Existing Narrative Consent Form
Status: COMPLETED
Conditions: Lumbar Radiculopathy
Interventions: PROCEDURE: Multimedia informed consent|PROCEDURE: Standard informed consent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of a Low-carbohydrate Tube Feed in Critically Ill Patients Under Insulin Therapy
Status: TERMINATED
Conditions: Aneurysmal Subarachnoid Hemorrhage
Interventions: OTHER: Diben 1.5 kcal HP|OTHER: Fresubin HP Energy Fibre (1.5 kcal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioavailability Study of SPARC1210 and Reference1210 in Subjects With Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: SPARC1210|DRUG: Reference1210
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PERMAD: Personalized Marker-driven Early Switch to Aflibercept in Patients With Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: BIOLOGICAL: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Citric Acid Passivation on Implant Abutments for the Prevention of Peri-implant Disease
Status: NOT_YET_RECRUITING
Conditions: Peri-Implantitis|Implant Infection|Microbial Disease
Interventions: PROCEDURE: Citric acid abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Study of Single-Dose Modified Release Glipizide in Healthy Volunteers
Status: RECRUITING
Conditions: Human Gastrointestinal Physiology Data
Interventions: DRUG: Glucotrol XL 5Mg Extended-Release Tablet|DRUG: Glipizide ER 5 MG 24 HR Extended Release Oral Tablet|DRUG: Rifaximin 200Mg Tab|DRUG: 13C6-Glipizide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetics And Relative Bioavailability Study Of Oxycodone in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Oxycodone|DRUG: Oxycodone|DRUG: Oxycodone|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 2 Study Investigating the Effect of EDP1815 in the Treatment of Mild to Moderate Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis|Plaque Psoriasis
Interventions: DRUG: EDP1815|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CT-guided Ablation of the Ganglion Impar for Pelvic Tumors: Comparethe Addition of Ketorolac or Dexamethasone
Status: COMPLETED
Conditions: Pain, Chronic
Interventions: PROCEDURE: ganglion impar block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Extension Study of GA-GCB ERT in Patients With Type 1 Gaucher Disease
Status: COMPLETED
Conditions: Gaucher Disease, Type 1
Interventions: BIOLOGICAL: VPRIV®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of tgAAC09, a Gag-PR-RT AAV HIV Vaccine
Status: COMPLETED
Conditions: HIV Infection
Interventions: BIOLOGICAL: tgAAC09
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Strengthening Neuro-Cognitive Skills for Success in School, Work and Beyond
Status: NOT_YET_RECRUITING
Conditions: TBI|Cognitive Dysfunction
Interventions: BEHAVIORAL: BrainStrong-GSR|BEHAVIORAL: BrainStrong-OPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omeprazole and Pantoprazole Antiplatelet Effect of Clopidogrel Clinical Trials(OPEN)
Status: UNKNOWN
Conditions: Acute Coronary Syndromes
Interventions: DRUG: omeprazole|DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bendamustine Plus Brentuximab Vedotin in HL and CD30+ PTCL in First Salvage Setting
Status: TERMINATED
Conditions: Lymphatic Diseases
Interventions: DRUG: Brentuximab Vedotin|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Level LASER Therapy With and Without Proprioceptive Stimulation Among Discogenic Lumbar Radiculopathy Patients
Status: RECRUITING
Conditions: Lumbar Radiculopathy
Interventions: OTHER: Low level laser therapy with proprioceptive stimulation|OTHER: Low level laser therapy without proprioceptive stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Baricitinib (LY3009104) in Participants With COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Baricitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: AIDS-Related Diffuse Large B-cell Lymphoma|AIDS-Related Non-Hodgkin Lymphoma|HIV Infection|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Grade 3b Follicular Lymphoma|Recurrent High Grade B-Cell Lymphoma|Recurrent Non-Hodgkin Lymphoma|Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma|Recurrent Transformed B-Cell Non-Hodgkin Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Grade 3b Follicular Lymphoma|Refractory High Grade B-Cell Lymphoma|Refractory Non-Hodgkin Lymphoma|Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma|Refractory Transformed B-Cell Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: Axicabtagene Ciloleucel|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arginase Inhibition in Ischemia-reperfusion Injury
Status: COMPLETED
Conditions: Coronary Artery Disease|Type 2 Diabetes Mellitus
Interventions: DRUG: N-hydroxy-nor-arginine|DRUG: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Electromyographic Analysis of Scapular Muscles During Closed Kinetic Chain Exercises
Status: COMPLETED
Conditions: Shoulder Pain|Shoulder Injuries|Activation, Patient
Interventions: DIAGNOSTIC_TEST: Superficial Electromyography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Understanding GRID Radiation Therapy Effects on Human Tumor Oxygenation and Interstitial Pressure to Increase Translation of Solid Tumor Therapy
Status: WITHDRAWN
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: 18F-MISO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Brain Oxygenation Monitoring in Patients Undergoing Coronary Artery Bypass Surgery
Status: TERMINATED
Conditions: Neurological Manifestations
Interventions: DEVICE: Optimizing hemodynamic and anesthetic parameters to improve cerebral perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Same-day ART Initiation Versus Standard of Care After Positive HIV-test Result in Rural Lesotho
Status: COMPLETED
Conditions: HIV Infection
Interventions: OTHER: Same-day ART initiation|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Single Oral Ascending Dose Study of BIA 9-1067 in Healthy Male Subjects
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: BIA 9-1067|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Trial on the Effects of Vitamin D Supplementation in Collegiate Swimmers and Divers
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Application of CO2 Insufflations in Colonoscopy Randomized Trial
Status: UNKNOWN
Conditions: Colorectal Neoplasm|Colorectal Cancer
Interventions: OTHER: CO2 insufflations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A JZP341 Study in Adult Participants With Advanced or Metastatic Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumor|Metastatic Solid Tumor
Interventions: DRUG: JZP341
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of a Test Troche Formulation of Fentanyl Citrate (400 mcg) Compared to Actiq® 400 mcg, Cephalon, Inc.
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Test fentanyl citrate 400 mcg troche|DRUG: Actiq 400 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DWP450 for Treating Moderate to Severe Glabellar Lines
Status: COMPLETED
Conditions: Moderate to Severe Glabellar Lines
Interventions: DRUG: DWP450|DRUG: Botox®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diversion to Treatment for Injection Drug Users Arrested for Possession of Heroin
Status: COMPLETED
Conditions: Cocaine-Related Disorders|HIV|Heroin Dependence
Interventions: DRUG: Methadone|DRUG: Buprenorphine|BEHAVIORAL: Employment-based drug abstinence reinforcement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Simulation-Based Training on Performance and Stress in the Clinical Setting
Status: UNKNOWN
Conditions: Spinal Puncture Complications|Simulation-based Training|Stress, Emotional
Interventions: OTHER: Simulation-based training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Comparison of the I-gel and Self-pressurised Air-Q Intubating Laryngeal Airway (Air-Q sp) in the Elderly Patients
Status: COMPLETED
Conditions: Supraglottic Airway Device
Interventions: DEVICE: Insertion of the i-gel|DEVICE: Insertion of the air-Q sp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Perioperative Protective Effects of Lidocaine
Status: TERMINATED
Conditions: Elective Surgical Procedure|Colorectal Surgery
Interventions: DRUG: lidocaine|DRUG: NaCl 0,9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis
Status: COMPLETED
Conditions: Pruritus|Atopic Dermatitis
Interventions: DRUG: difelikefalin 0.25 mg|DRUG: difelikefalin 0.5 mg|DRUG: difelikefalin 1.0 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Do AxoGuard Implants Decrease Shoulder Disability After Neck Dissections
Status: UNKNOWN
Conditions: Spinal Accessory Nerve Injury|Cervical Lymphadenopathy
Interventions: DEVICE: AxoGuard Nerve Cuff
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Effect of the Emotional Freedom Technique on Perceived Pain, Situational Anxiety, Cortisol and Satisfaction Levels in Mammography Screening.
Status: NOT_YET_RECRUITING
Conditions: Mammography Screening|Pain|Anxiety
Interventions: OTHER: Emotional Freedom Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Cosmetic Results, Quality of Life and Patient Satisfaction Achieved With Round-block and Retroglandular Oncoplastic Breast Conserving Surgeries
Status: RECRUITING
Conditions: Breast Cancer|Quality of Life|Patient Satisfaction
Interventions: PROCEDURE: Round-block Oncoplastic Breast Conserving Surgeries|PROCEDURE: Retroglandular Oncoplastic Breast Conserving Surgeries
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Proximity-incentive Strategy for Cervical Cancer Screening
Status: COMPLETED
Conditions: Cervical Cancer|Uterine Cervical Disease|Human Papilloma Virus
Interventions: BEHAVIORAL: Proximity-incentive strategy based on vaginal self-sampling for women 50 to 65 years who do not participate to cervical cancer screening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Gender-Enhanced Pre-Exposure Prophylaxis (PrEP) Information-Motivational Workshop for Young South African Women
Status: UNKNOWN
Conditions: HIV Infections
Interventions: BEHAVIORAL: Gender-Enhanced -- Masibambane|BEHAVIORAL: Individually accessed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ridaforolimus With Cetuximab: Adv Non-Small Cell Lung, Colorectal, Head & Neck Cancer
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Ridaforolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selenium in the Treatment of Arsenic Toxicity and Cancers
Status: COMPLETED
Conditions: Arsenical Melanosis|Arsenical Keratosis|Arsenical Cancers|Arsenicosis|Arsenic Exposure|Arsenic Toxicity|Arsenic Poisoning
Interventions: DRUG: sodium selenite|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of AZD3366 in Healthy Subjects, Japanese and Chinese Subjects
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: AZD3366|DRUG: Placebo|DRUG: Ticagrelor|DRUG: acetylsalicylic acid (ASA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Teens-Connect: Preventive Psycho-education for Transitioning Teens With Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: BEHAVIORAL: Teens-Connect|BEHAVIORAL: Planet D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Group Dialectical Behavior Therapy as add-on Treatment for Adults With Attention Deficit/Hyperactive Disorder
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Skill Training Group of the Dialectical Behavior Therapy|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enzalutamide, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV or Recurrent Endometrioid Endometrial Cancer
Status: COMPLETED
Conditions: Recurrent Endometrial Endometrioid Adenocarcinoma|Recurrent Uterine Corpus Carcinoma|Stage III Uterine Corpus Cancer AJCC v7|Stage IIIA Uterine Corpus Cancer AJCC v7|Stage IIIB Uterine Corpus Cancer AJCC v7|Stage IIIC Uterine Corpus Cancer AJCC v7|Stage IV Uterine Corpus Cancer AJCC v7|Stage IVA Uterine Corpus Cancer AJCC v7|Stage IVB Uterine Corpus Cancer AJCC v7
Interventions: DRUG: Carboplatin|DRUG: Enzalutamide|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Coffee Consumption on Metabolic Markers in Adults With Prediabetes and Obesity
Status: RECRUITING
Conditions: Prediabetes
Interventions: DIETARY_SUPPLEMENT: Coffee capsule|DIETARY_SUPPLEMENT: Corn starch capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of TAS0728 in Patients With Solid Tumors With HER2 or HER3 Abnormalities
Status: TERMINATED
Conditions: Advanced Solid Tumors With HER2 Abnormalities|Advanced Solid Tumors With HER3 Abnormalities
Interventions: DRUG: TAS0728
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics, Brain Structure and Psychological Variables
Status: COMPLETED
Conditions: Depressive Symptoms|Anxiety|Stress
Interventions: DIETARY_SUPPLEMENT: Vivomixx® powder|OTHER: Placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 2 Study of Radiprodil in Subjects With Drug-resistant Infantile Spasms (IS)
Status: TERMINATED
Conditions: Infantile Spasms (IS)
Interventions: DRUG: Radiprodil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Static Stretching Exercises and Ultrasound Elastography Evaluation
Status: COMPLETED
Conditions: Hamstring Muscle|Muscle Stretching Exercise|Elastography
Interventions: OTHER: Mulligan bent leg raise technique|OTHER: Static stretching exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of the Interventions Using Multiple Sensory Integrations on Preterm Infants' Stress-Related Outcomes
Status: COMPLETED
Conditions: Preterm Infants|Pain
Interventions: OTHER: Multiple Sensory Integrations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Remote Monitoring and Follow-up for Postpartum Hypertensive Disorders of Pregnancy
Status: COMPLETED
Conditions: Hypertensive Disorder of Pregnancy|Preeclampsia|Gestational Hypertension
Interventions: OTHER: QI project- usage of RPM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Gyn Onc Prehab Study
Status: COMPLETED
Conditions: Gynecologic Cancer|Ovarian Cancer|Endometrial Cancer|Cervical Cancer|Surgery|Treatment Adherence|Quality of Life
Interventions: OTHER: Unimodal|OTHER: Trimodal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Comparing Etanercept With Usual DMARD Therapy in Subjects With Rheumatoid Arthritis in the Asia Pacific Region
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Etanercept , Methotrexate|DRUG: Methotrexate; sulfasalazine; hydroxychloroquine;leflunomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Atorvastatin on Carotid Intima Media Thickness
Status: UNKNOWN
Conditions: Essential Hypertension|Hypercholesterolemia
Interventions: DRUG: Perindopril/Amlodipine and Perindopril/Amlodipine/Atorvastatin treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closed-loop System for Oxygen Delivery and Exercise in Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: COPD|Oxygen Therapy|Hypercapnia
Interventions: DEVICE: Automated settings on the oxygen delivery device|DEVICE: Manual settings with FreeO2 system in collection mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel
Status: RECRUITING
Conditions: Bowel; Stricture
Interventions: COMBINATION_PRODUCT: GIE Medical ProTractX3 TTS DCB|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Patients With Body Image Issues Treated With 2 Different Behavioral Interventions
Status: UNKNOWN
Conditions: Body Dysmorphic Disorders
Interventions: BEHAVIORAL: Crooked Mirror Externalization Therapy|BEHAVIORAL: Mirror Retraining Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PULSed Field ablAtion of coloRectal Polyps
Status: NOT_YET_RECRUITING
Conditions: Colon Polyp
Interventions: DEVICE: Irreversible Electroporation using EndoVE(Endoscopic Vacuum Electrode) and electrical pulses generated using ePORE(electroporation device)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neoadjuvant Chemoimmunotherapy in Stage IIIA- N2IIIB Non-small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Non-small Cell Lung Cancer Stage ⅢA|Non-small Cell Lung Cancer Stage IIIB
Interventions: OTHER: cycles of neoadjuvant therapy and duration of waiting for surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact of Group Commitment Contracts on Smoking Cessation and Weight Loss
Status: SUSPENDED
Conditions: Smoking Cessation|Weight Loss
Interventions: BEHAVIORAL: Group Commitment Contract|BEHAVIORAL: Individual Monetary Rewards|BEHAVIORAL: Individual Commitment Contract|OTHER: Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Open-Label Study to Evaluate the Safety, Tolerability, and PK of Aramchol in Subjects With Hepatic Impairment
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Aramchol free acid tablet 600mg, single dose|DRUG: Aramchol free acid tablet 300mg, bid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Work be Organized to Become More Health Promoting for Employees in Home Care Services?
Status: COMPLETED
Conditions: Occupational Exposure|Musculoskeletal Pain|Work-related Injury|Low Back Pain|Shoulder Pain|Neck Pain
Interventions: BEHAVIORAL: Goldilocks work principle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of the Effects of a 24-hour Cold and Heat Exposure on the Factors Influencing Food Intake
Status: RECRUITING
Conditions: Eating Habit|Cold Exposure|Heat
Interventions: OTHER: Heat exposure (32°C)|OTHER: Cold exposure (16°C)|OTHER: Thermoneutral exposure (24°C)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Cavosonstat (N91115) in CF Patients Who Are Heterozygous for F508del-CFTR and a Gating Mutation and Being Treated With Ivacaftor
Status: UNKNOWN
Conditions: Cystic Fibrosis
Interventions: DRUG: Cavosonstat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 3D-Printed Versus Laboratory-Fabricated Hyrax Expanders
Status: RECRUITING
Conditions: Maxillary Expansion
Interventions: DEVICE: 3D-Printed Hyrax Expander|DEVICE: Conventional Laboratory Fabricated Hyrax Expander
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Formative Study to Explore the Sensory Perceptions of Vaginal Product Users
Status: COMPLETED
Conditions: Microbicide Delivery System Acceptability
Interventions: OTHER: high volume gel|OTHER: low volume gel|OTHER: vaginal film
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dose-Escalation and Dose-Expansion Study to Evaluate the Safety and Tolerability of Anti-CD7 Allogeneic CAR T-Cells (WU-CART-007) in Patients With CD7+ Hematologic Malignancies
Status: RECRUITING
Conditions: T-Cell Non-Hodgkin Lymphoma|Acute Myeloid Leukemia|Angioimmunoblastic T-cell Lymphoma|Enteropathy-Associated T-Cell Lymphoma|Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma|Peripheral T Cell Lymphoma|Anaplastic Large Cell Lymphoma|Adult T Cell Leukemia|Adult T Cell Lymphoma|T Cell Prolymphocytic Leukemia|Extranodal NK/T-cell Lymphoma|Transformed Mycosis Fungoides|Sezary Syndrome|Primary Cutaneous Gamma-Delta T-Cell Lymphoma|Hepatosplenic T-cell Lymphoma
Interventions: BIOLOGICAL: WU-CART-007
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mometasone Furoate on Sleep Disturbances in Subjects With Seasonal Allergic Rhinitis (Study P04608) (COMPLETED)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Mometasone Furoate Nasal Spray (MFNS)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Standard Care vs. COrticosteroid for REtinal Vein Occlusion (SCORE) Study
Status: COMPLETED
Conditions: Macular Edema, Cystoid|Retinal Vein Occlusion
Interventions: OTHER: Standard Care|DRUG: intravitreal triamcinolone injection|DRUG: intravitreal triamcinolone injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Control Trial Examining Two Treatments for Problem Gambling
Status: WITHDRAWN
Conditions: Gambling, Pathological|Anger
Interventions: BEHAVIORAL: Emotion and Behaviour Regulation Treatment (EBRT)|BEHAVIORAL: Cognitive Behavioural Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Visual Attention in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DEVICE: Active anodal tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: JNJ-68284528|DRUG: Pomalidomide|DRUG: Bortezomib|DRUG: Dexamethasone|DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy for Adolescents With Social Anxiety Disorder
Status: UNKNOWN
Conditions: Social Anxiety Disorder
Interventions: BEHAVIORAL: Cool Kids Anxiety Program - Social Enhanced|BEHAVIORAL: Cool Kids Anxiety Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study on Suprapubic Catheterization Versus Transurethral Catheterization in Laparoscopic Surgery for Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer|Surgery
Interventions: DEVICE: Suprapubic catheterization using central venous catheter(CVC-2 7F)|DEVICE: Transurethral catheterization using Foley catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Fructose Ingestion and the Renin Angiotensin System in Humans
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: Fructose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: HIPEC and Systemic Chemotherapy Combined With Apatinib in Unresectable Peritoneal Metastases From Gastric Cancer
Status: TERMINATED
Conditions: Peritoneal Metastases From Gastric Cancer
Interventions: PROCEDURE: exploratory laparoscopy or laparotomy|PROCEDURE: HIPEC|DRUG: Systemic chemotherapy|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Esomeprazole on the Pharmacokinetics of Oral Treprostinil
Status: COMPLETED
Conditions: Hypertension, Pulmonary|Pulmonary Arterial Hypertension
Interventions: DRUG: Treprostinil diethanolamine|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Pilot Study of Octreotide, a Somatostatin Octapeptide Analog, for Gastrointestinal Hemorrhage in Hormone-Refractory Hereditary Hemorrhagic Telangiectasia and Senile Ectasia
Status: COMPLETED
Conditions: Hereditary Hemorrhagic Telangiectasia|Ectasia
Interventions: DRUG: octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Operative Hysteroscopy Versus Suction Curettage for Surgical Termination of Early Pregnancy Loss (Miscarriage)
Status: RECRUITING
Conditions: Early Pregnancy Loss|Intrauterine Adhesion
Interventions: PROCEDURE: Operative hysteroscopy (by tissue removal device)|PROCEDURE: Suction curettage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of PEEP on Arterial Oxygen Partial Pressure in Elderly Patients With Lithotomy Position Using LMA Supreme™
Status: COMPLETED
Conditions: Urinary Bladder Neoplasms|Prostatic Neoplasms
Interventions: OTHER: PEEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Trial of Stereotactic Body Radiotherapy Followed by Ipilimumab in Treating Patients With Stage IV Melanoma
Status: TERMINATED
Conditions: Recurrent Melanoma|Stage IV Skin Melanoma
Interventions: BIOLOGICAL: Ipilimumab|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Docetaxel With Radiation in Adults With Soft Tissue Sarcoma of the Extremities
Status: SUSPENDED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Gemcitabine|DRUG: Docetaxel|RADIATION: Radiation|PROCEDURE: Surgical Resection|OTHER: Blood draws
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cemented Marathon/Corail Versus Pinnacle/Corail
Status: UNKNOWN
Conditions: Arthritis of the Hip
Interventions: DEVICE: Pinnacle/Corail with collar|DEVICE: Marathon/Corail with collar|DEVICE: Pinnacle/Corail without collar|DEVICE: Marathon/Corail without collar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Electronic Training Program for Orienting and Interpreting [18F]Flutemetamol Positron Emission Tomography (PET) Images
Status: COMPLETED
Conditions: Alzheimer's Disease|Mild Cognitive Impairment
Interventions: DRUG: [18F]Flutemetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study to Determine the Feasibility of Fluconazole for Induction Treatment and Suppression of Relapse of Histoplasmosis in Patients With the Acquired Immunodeficiency Syndrome
Status: COMPLETED
Conditions: HIV Infections|Histoplasmosis
Interventions: DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Abdominal Cushion on PCNL in Prone Position
Status: UNKNOWN
Conditions: Kidney Stone
Interventions: DEVICE: Percutaneous Nephrolithotomy without an abdominal cushion|DEVICE: Percutaneous Nephrolithotomy with an 5 cm abdominal cushion|DEVICE: Percutaneous Nephrolithotomy with an 5 cm abdominal cushion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Progesterone Versus Vaginal Progesterone for Endometrial Preparation in Fresh Donated Oocytes Recipients
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: subcutaneous progesterone|DRUG: vaginal progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bread Replacement - Facing the Challenge to Improve Its Quality for Better Metabolic Health
Status: COMPLETED
Conditions: Bread|Hyperglycemia|Glycemic Control|PreDiabetes
Interventions: OTHER: Beta-glucan bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Suicide Prediction and Prevention for People at Risk for Opioid Use Disorder: Supplement to COMPUTE 2.0
Status: COMPLETED
Conditions: Opioid Use|Opioid-use Disorder|Suicide
Interventions: OTHER: OUD-CDS + Suicide Risk Model associated CDS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Revascularization in Patients Undergoing Transcatheter Aortic Valve Implantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease|Aortic Valve Stenosis|TAVI|PCI
Interventions: PROCEDURE: PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluorescent Aided Resection and Evaluation of Soft Tissue Sarcomas (FLARES)
Status: WITHDRAWN
Conditions: Soft Tissue Sarcoma|Soft Tissue Sarcoma Adult
Interventions: DRUG: Aminolevulinic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aortic Stenosis With COmplex PCI (ASCOP) Features Retrospective Registry on Contemporary Management and Outcomes
Status: COMPLETED
Conditions: Aortic Valve Stenosis|Transcatheter Aortic Valve Replacement|Angioplasty, Balloon, Coronary|Coronary Artery Disease
Interventions: PROCEDURE: Transcatheter aortic valve intervention (TAVI) and percutaneous coronary intervention (PCI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Value of Home Chlorhexidine Pre-Surgical Wash Before Spine Surgery
Status: COMPLETED
Conditions: Infection|Spinal Injuries
Interventions: DEVICE: Chlorhexidine Wipes|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of LY01008 and Bevacizumab Combined With Paclitaxel and Carboplatin for Treatment of Naïve Subjects With Metastatic or Recurrent Nonsquamous Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer|Non Small Cell Lung Cancer Metastatic|Non Small Cell Lung Cancer Recurrent
Interventions: DRUG: LY01008|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Henagliflozin Reducing Infarct Size After Priamry PCI in Patients With ST Segment Elevation Myocardial Infarction
Status: RECRUITING
Conditions: Myocardial Infarction|Heart Failure
Interventions: DRUG: Henagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Visual Performance of Two Monofocal Intraocular Lenses
Status: COMPLETED
Conditions: Catartact
Interventions: DEVICE: Implantation of CT LUCIA IOL|DEVICE: Implantation of Acrysof IQ SN60WF IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Before or After Surgery in Treating Patients With Colorectal Cancer With Liver Metastases That Could Be Removed By Surgery
Status: TERMINATED
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: PROCEDURE: Postoperative chemotherapy|PROCEDURE: Perioperative chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Management in Children and Young Adults With Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Me & You-Tech: A Socio-Ecological Solution to Teen Dating Violence for the Digital Age
Status: ENROLLING_BY_INVITATION
Conditions: Adolescent Behavior|Interpersonal Relations|Domestic Violence|Physical Violence
Interventions: BEHAVIORAL: Me & You - Tech
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Minimizing Light Exposure Intensity on Macular Function After Cataract Surgery in Patients With Early or Intermediate AMD
Status: COMPLETED
Conditions: Macular Degeneration, Age Related|Cataract
Interventions: DEVICE: NGenuity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION