pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comprehensive Protocol for Treatment of Upper Limb Spasticity in Post-stroke Hemiplegic Patients
Status: COMPLETED
Conditions: Post-stroke Upper Limb Spasticity
Interventions: PROCEDURE: Low-frequency transcranial electrical stimulation; Paraspinous block; Dry needling of spastic upper limb muscles; Muscular functional electrical stimulation (FES)|PROCEDURE: SHAM Low-frequency transcranial electrical stimulation; Paraspinous block; Dry needling of spastic upper limb muscles; Muscular functional electrical stimulation (FES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Qualitative and Quantitative Study Which Aims to Determine the Specifics of the Announcement for the Diagnosis of Patients With Craniosynostosis and Their Parents to Better Support Them in Their Care
Status: COMPLETED
Conditions: Craniosynostosis
Interventions: OTHER: qualitative survey|OTHER: quantitative survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Remote Ischemic Preconditioning on Cognitive Function After Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Surgery
Interventions: PROCEDURE: Remote Ischemic Preconditioning|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CSD201204 An Actual Use Study of P12 Electronic Nicotine Delivery System Among U.S. Adult Smokers
Status: COMPLETED
Conditions: Smoking, Tobacco
Interventions: OTHER: P1213416|OTHER: P1213422|OTHER: P1213716|OTHER: P1213722|OTHER: P1211216|OTHER: P1211222|OTHER: P1213616|OTHER: P1213622|OTHER: P1213816|OTHER: P1213822|OTHER: P1211916|OTHER: P1211922
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dose Ranging Study of Lunsekimig Compared With Placebo-control in Adult Participants With Moderate-to-severe Asthma
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: Lunsekimig|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Adults and Adolescents With Angelman Syndrome (STARS)
Status: COMPLETED
Conditions: Angelman Syndrome
Interventions: DRUG: OV101 Regimen 1|DRUG: OV101 regimen 2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin and Lenalidomide in Treating Patients With Relapsed or Refractory T-Cell Lymphomas
Status: WITHDRAWN
Conditions: CD30-Positive Neoplastic Cells Present|Folliculotropic Mycosis Fungoides|Recurrent Mycosis Fungoides|Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma|Refractory Mycosis Fungoides|Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma|Sezary Syndrome
Interventions: DRUG: Brentuximab Vedotin|DRUG: Lenalidomide|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Etodolac-Lidocaine Patch in the Treatment of Acute Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Etoreat®(Etodolac-Lidocaine Topical Patch)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TJ-68 Clinical Trial in Patients With Amyotrophic Lateral Sclerosis (ALS) and Muscle Cramps
Status: ACTIVE_NOT_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis|Muscle Cramp
Interventions: DRUG: TJ-68|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Imaging Informed Radiation Dose Escalation to Sites of Recurrent Disease and De-escalation to Uninvolved Areas in Salvage Radiotherapy for Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Image-guided Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Two Adjuvanted Dose Levels of Panblok H7+MF59 Compared for Immunogenicity and Safety With an Unadjuvanted Dose of Panblok H7 in Participants 18 Years of Age and Older
Status: COMPLETED
Conditions: Influenza|Healthy Volunteers
Interventions: BIOLOGICAL: Panblok + MF59 Dose 1|BIOLOGICAL: Panblok + MF59 Dose 2|BIOLOGICAL: Unadjuvanted Panblok Dose 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficiency of Imatinib Treatment Maintenance or Interruption After 3 Years of Adjuvant Treatment in Patients With Gastrointestinal Stromal Tumours (GIST)
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors|Resected Gastrointestinal Stromal Tumors|Non-metastatic|High Risk of Recurrence|KIT Gene Mutation
Interventions: DRUG: Imatinib maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dose-staged Gamma Knife Radiosurgery Versus Microsurgical Resection
Status: RECRUITING
Conditions: Brain Metastases
Interventions: PROCEDURE: Microsurgical resection|PROCEDURE: Gamma Knife radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of ILB2109 and Toripalimab in Patients With Advanced Solid Malignancies
Status: RECRUITING
Conditions: Head and Neck Cancer|Cervical Cancer|Endometrial Cancer|Triple Negative Breast Cancer|Ovarian Cancer|Soft Tissue Sarcoma|Melanoma|Nasopharyngeal Carcinoma|Non Small Cell Lung Cancer|Classic Hodgkin Lymphoma
Interventions: DRUG: ILB-2109|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tyrosine Kinase Inhibitor Orelabrutinib (ICP-022) in Patients With r/r B-Cell Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Part 1：r/r B-cell Malignancies|Part 2：B-cell Malignancies
Interventions: DRUG: Orelabrutinib (ICP-022)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Covered Self-expandable Metal Stents for Palliation of Malignant Biliary Strictures: Evaluation of a New Type of Stent
Status: COMPLETED
Conditions: Malignant Biliary Strictures
Interventions: DEVICE: Endoscopic retrograde cholangiography (ERC) (ComVi biliary stent)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Delayed Dinner, Exercise and Glucose Metabolism
Status: RECRUITING
Conditions: Normal Dinner|Delayed Dinner|Exercise Plus Delayed Dinner
Interventions: BEHAVIORAL: Normal dinner|BEHAVIORAL: Delayed dinner consumption|BEHAVIORAL: Exercise with delayed dinner consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Biomarkers of Response to Taxotere in HRPC. ICORG 08-08, V2
Status: COMPLETED
Conditions: Metastatic Cancer|Prostate Cancer
Interventions: DRUG: docetaxel|GENETIC: RNA analysis|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: circulating tumor cell analysis|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of TMC278 in Human Immunodeficiency Virus Type 1 Infected Patients, Who Are Not Treated With Antiretroviral Medicines
Status: COMPLETED
Conditions: Human Immunodeficiency Virus Type 1
Interventions: DRUG: TMC278 25 mg|DRUG: TMC278 75 mg|DRUG: TMC278 150 mg|DRUG: Efavirenz|DRUG: Non-nucleoside reverse transcriptase inhibitor (NRTIs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Saxagliptin on Pre-Diabetes Mellitus and Obesity
Status: UNKNOWN
Conditions: Prediabetes
Interventions: DRUG: Saxagliptin|DRUG: saxagliptin|DRUG: metformin|OTHER: lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SARS-CoV-2-Neutralizing Monoclonal COVID-19 Antibody DZIF-10c by Inhalation
Status: COMPLETED
Conditions: SARS-CoV-2 Infection
Interventions: BIOLOGICAL: DZIF-10c|BIOLOGICAL: DZIF-10c|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Versus Interscalene Blocks for Shoulder Surgery
Status: COMPLETED
Conditions: Anesthesia, Local|Phrenic Nerve Paralysis|Upper Extremity Injury|Shoulder Injury
Interventions: PROCEDURE: Interscalene brachial plexus nerve block|PROCEDURE: Erector spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnesium Sulfate as an Adjuvant to Propofol During Consious Sedation in Colonoscopy
Status: NOT_YET_RECRUITING
Conditions: Magnesium|Intraoperative Analgesia
Interventions: DRUG: Magnesium Sulfate|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Metformin Plus TKI Use in Patients With Non-Small Cell Lung Carcinoma
Status: UNKNOWN
Conditions: Non-Small Cell Adenocarcinoma|Tyrosine Kinase Mutation|EGFR Gene Mutation
Interventions: DRUG: Metformin|DRUG: TKI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effects of Vortioxetine (Lu AA21004) on the Concentrations of Selected Neurotransmitters in Healthy Male Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Vortioxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Expanding Coverage of Severe Acute Malnutrition (SAM) Treatment in Kenya
Status: NOT_YET_RECRUITING
Conditions: Acute Malnutrition, Severe|Malnutrition, Child|Wasting
Interventions: BEHAVIORAL: SWITCH intervention package
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Computerized Cognitive Behavioral Therapy for Childhood Anxiety in Community Health Centers
Status: COMPLETED
Conditions: Generalized Anxiety Disorder|Social Phobia|Separation Anxiety Disorder
Interventions: BEHAVIORAL: Computerized Cognitive Behavioral Therapy|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 6 Month Study of Once Daily Ciclesonide Hydrofluoroalkane (HFA) Nasal Aerosol in The Treatment of Perennial Allergic Rhinitis (PAR) in Subjects 12 Years and Older
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: ciclesonide HFA 160 μg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Acetylcysteine for the Treatment of Acute Uncomplicated Rhinosinusitis
Status: COMPLETED
Conditions: Rhinosinusitis
Interventions: DRUG: acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Stage-matched Intervention Based on Transtheoretical Model of Change in Changing the Videogaming Behavior
Status: ENROLLING_BY_INVITATION
Conditions: Video Game Addiction
Interventions: BEHAVIORAL: Stage-matched interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Profile of BIA 6-512 in Healthy Elderly Subjects Versus Healthy Young Subjects
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: 200 mg BIA 6-512
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Japanese Single and Multiple Ascending Dose, Safety, Tolerability, Pharmacokinetic (PK) & Pharmacodynamic (PD) Study of AZD7687
Status: COMPLETED
Conditions: Type 2 Diabetes|Obesity
Interventions: DRUG: AZD7687
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Women After Severe Postpartum Haemorrhage
Status: COMPLETED
Conditions: Severe Postpartum Haemorrhage
Interventions: DRUG: Iron isomaltoside 1000|DRUG: Red blood cell transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Trial Protocol for the Inactivated Poliomyelitis Vaccine Made From Sabin Strains (IPV)
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: Inactivated Poliomyelitis Vaccine (Sabin strains)|BIOLOGICAL: Inactivated Poliomyelitis Vaccine (Sabin strains)|BIOLOGICAL: Inactivated Poliomyelitis Vaccine (Sabin strains)|BIOLOGICAL: Oral Poliomyelitis Vaccine|BIOLOGICAL: Inactivated Poliomyelitis Vaccine (Salk strains).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intravenous Metoclopramide for the Treatment of Post Concussive Headache: a Randomized Placebo Controlled Trial
Status: UNKNOWN
Conditions: Post Concussive Headache|Post Concussive Syndrome
Interventions: DRUG: metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Continuous Proximal Adductor Canal vs Continuous Femoral Nerve Block for Postoperative Pain Control and Rehabilitation Following Total Knee Arthroplasty
Status: WITHDRAWN
Conditions: Total Knee Arthroplasty
Interventions: PROCEDURE: Continuous proximal adductor canal block|PROCEDURE: Continuous femoral nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnosing Heart Failure With Preserved Ejection Fraction in Patients With Unexplained Dyspnea (Diagnose-HFpEF)
Status: ACTIVE_NOT_RECRUITING
Conditions: Dyspnea
Interventions: DIAGNOSTIC_TEST: Invasive hemodynamics of left ventricle via conductance catheter at rest, with exercise and with temporary vena cava occlusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dutasteride 0.5mg For The Treatment Of Chinese Patients With Benign Prostatic Hyperplasia (BPH)
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia|Prostatic Hyperplasia
Interventions: DRUG: Dutasteride 0.5mg capsule|DRUG: Dutasteride matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib Study of YY-20394 in Participants With B-cell Hematologic Malignancies
Status: COMPLETED
Conditions: Small Lymphocytic Lymphoma|Lymphoplasmacytic Lymphoma|Marginal Zone Lymphoma|Mantle Cell Lymphoma|Diffuse Large B Cell Lymphoma
Interventions: DRUG: YY-20394
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Two Intensive Walking Training Interventions in Community Dwelling Individuals With History of Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Motor Learning Walking Program|BEHAVIORAL: Body Weight Supported Treadmill Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Characteristics and Safety After Administration of NVP-2002
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: NVP-2002-R1+NVP-2002-R2|DRUG: NVP-2002
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cross-education for Proximal Humerus Fracture Rehabilitation
Status: TERMINATED
Conditions: Proximal Humerus Fractures (to be Managed Non-operatively)
Interventions: OTHER: Cross-education of strength-training|OTHER: Usual rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Study of a Mouthwash Based on Schinus Terebinthifolius to Treat Gingivitis in Children
Status: UNKNOWN
Conditions: Gingivitis|Plaque Accumulation
Interventions: BIOLOGICAL: Use of natural product (Schinus terebinthifolius)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Does a Seven Day Treatment With Dipyridamole Induce Protection Against Ischemia-Reperfusion Injury?
Status: COMPLETED
Conditions: Ischemia-Reperfusion Injury|Atherosclerosis
Interventions: DRUG: dipyridamole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Injectable Platelet Rich Fibrin With Connective Tissue Graft for the Treatment of Deep Gingival Recession Defects.
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: CAF+CTG+i-prf
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Delivering a Multi-disease Screening Tool to Migrant Populations
Status: RECRUITING
Conditions: Hiv|Hepatitis B|Hepatitis C|Tuberculosis|Chagas Disease|Schistosomiasis|Strongyloidiasis|Female Genital Mutilation Type I Status|Female Genital Mutilation Type II Status|Female Genital Mutilation Type III Status
Interventions: OTHER: Clinical decision support system for screening of migrants using the ISMiHealth software tool.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Dasatinib Versus Nilotinib for Treatment Naïve Chronic Myeloid Leukemia
Status: TERMINATED
Conditions: Chronic Myeloid Leukemia - Chronic Phase
Interventions: DRUG: Dasatinib 100 MG [Sprycel]|DRUG: Nilotinib 150mg oral capsule [Tasigna]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Topical Application of Lidacaine Spray Prior to IUD Insertion
Status: UNKNOWN
Conditions: Drug Usage
Interventions: DRUG: Lidocaine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Influence of Timing of Cabergoline Initiation on Prevention of OHSS
Status: UNKNOWN
Conditions: Ovarian Hyperstimulation Syndrome
Interventions: DRUG: Late Cabergoline 0.5mg|DRUG: Early Cabergoline 0.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety Study of Dapivirine (TMC120) Vaginal Microbicide Gel in Belgium
Status: COMPLETED
Conditions: HIV Infections|HIV-1
Interventions: DRUG: dapivirine (TMC120) vaginal gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Short-term Effect of a New Nordic Renal Diet on Phosphorus Homeostasis in CKD Stage 3-4
Status: COMPLETED
Conditions: Chronic Kidney Disease, Stage 3 (Moderate)
Interventions: DIETARY_SUPPLEMENT: New Nordic Renal Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Decision Support for Blood Transfusions to Improve Guideline Adherence
Status: RECRUITING
Conditions: Anemia|Thrombocytopenia|Coagulopathy, Mild|Hypofibrinogenemia
Interventions: BEHAVIORAL: Clinical Decision Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Group Psychoeducational Program for Mothers of Children With High Functional Pervasive Developmental Disorders
Status: UNKNOWN
Conditions: Pervasive Developmental Disorder
Interventions: OTHER: Family psychoeducational therapy plus TAU|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Investigation of a B12 Vitamin to Increase Energy and Focus
Status: COMPLETED
Conditions: B12 Deficiency Vitamin|Energy Supply; Deficiency|Mood
Interventions: DIETARY_SUPPLEMENT: Hype Bites Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase 1 Study of an Investigational Drug, ALN-AT3SC, in Healthy Volunteers and Hemophilia A or B Patients
Status: COMPLETED
Conditions: Hemophilia A|Hemophilia B
Interventions: DRUG: ALN-AT3SC|DRUG: Sterile Normal Saline (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of GTX-104 Compared With Oral Nimodipine in Patients With aSAH
Status: RECRUITING
Conditions: Aneurysmal Subarachnoid Hemorrhage (aSAH)
Interventions: DRUG: GTX-104|DRUG: Nimotop 30 MG Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Expression of FcγRIIa and Arterial Hemodynamics to Predict Recurrent Stroke in Intracranial Atherosclerosis
Status: RECRUITING
Conditions: Stroke|TIA|Ischemic Stroke|Ischemic
Interventions: DIAGNOSTIC_TEST: Medical Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EMBr Wave for the Reduction of Hot Flashes in Women With a History of Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Carcinoma|Breast Ductal Carcinoma In Situ|Breast Lobular Carcinoma In Situ|Hot Flashes
Interventions: DEVICE: EMBr Wave|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Research Study to Compare Two Types of Insulin: Insulin 287 and Insulin Glargine in People With Type 2 Diabetes Who Have Not Used Insulin Before
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin icodec|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Clostridium Difficile Infections Using Lactobacillus Plantarum 299v Strain
Status: UNKNOWN
Conditions: Clostridium Difficile
Interventions: DIETARY_SUPPLEMENT: Prevention of C. difficile infections using LP299v strain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Vaccine Responses to Influenza A H1N1/09 Immunization in High-risk Patients
Status: COMPLETED
Conditions: HIV Infection|Rheumatic Disease|Cancer|Transplant|Pediatrics
Interventions: BIOLOGICAL: Adjuvanted influenza A(H1N1) vaccines
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neuroprotective Effects of iTBS in PD
Status: RECRUITING
Conditions: Neuroprotection|Parkinson Disease|Intermittent Theta Burst Stimulation
Interventions: DEVICE: intermittent theta burst stimulation|DEVICE: sham iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation (FMT) as a Prophylaxis of Necrotizing Enterocolitis (NEC) - Clinical Study
Status: NOT_YET_RECRUITING
Conditions: Necrotizing Enterocolitis
Interventions: DRUG: Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Opioid Free Versus Opioid Based Anaesthesia for Free Flap Reconstruction Surgery of the Breast: A Phase III Multicentric Randomized Controlled Study.
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Scapulothoracic and Glenohumeral Stabilization Exercises in Boulderers
Status: UNKNOWN
Conditions: Sports Physical Therapy
Interventions: OTHER: Scapulothoracic and glenohumeral stabilization exercises|OTHER: Glenohumeral stability exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Carboplatin Plus Etoposide With or Without SHR-1316 in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC)
Status: UNKNOWN
Conditions: Extensive-stage Small Cell Lung Cancer
Interventions: DRUG: SHR-1316|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Trial of Voyager V1 in Combination With Cemiplimab in Cancer Patients
Status: RECRUITING
Conditions: Melanoma|Head and Neck Squamous Cell Carcinoma|Colo-rectal Cancer
Interventions: BIOLOGICAL: VV1|BIOLOGICAL: Cemiplimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Nutritional Solution to Improve Intestinal Permeability in Celiac Patients
Status: COMPLETED
Conditions: Celiac Disease
Interventions: DIETARY_SUPPLEMENT: Protalsafe|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Action of MOBIDERM® on Periarticular Edema After Total Knee Prosthesis - Randomized Controlled
Status: COMPLETED
Conditions: Edema|Arthroplasty, Replacement, Knee
Interventions: DEVICE: MOBIDERM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Efficacy and Safety of Sodium-glucose Cotransporter 2 Inhibitors in Patients With Acute Kidney Disease
Status: NOT_YET_RECRUITING
Conditions: Acute Kidney Injury
Interventions: DRUG: dapagliflozin|OTHER: Other anti-diabetic drug or no anti-diabetic drug|DRUG: empagliflozin|DRUG: canagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Concurrent TACE and Sorafenib in Patients With HCC and Extrahepatic Metastasis (COTSOM Study)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Metastasis
Interventions: PROCEDURE: Conventional Transarterial Chemoembolization (TACE)|DRUG: sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of Concurrent Radiotherapy in Elderly Patients With Esophageal Squamous Cell Carcinoma (ESO-Shanghai 15)
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma|Chemoradiotherapy|Survival
Interventions: DRUG: Paclitaxel plus carboplatin|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A SAD Study to Evaluate the Safety, Tolerability and PK/PD of iN1011-N17 in Healthy Volunteers
Status: COMPLETED
Conditions: Osteoarthritis|Pain|Post Herpetic Neuralgia|Neuropathic Pain|Chronic Pain|Nav 1.7
Interventions: DRUG: iN1011-N17|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Randomized Control Trial in Children With Moderate to Severe Atopic Dermatitis to Assess the Benefit of a Nurse-led One-to-one Education Program in Addition to Standard Care Compared to Standard Care Alone on the Long Term Control of Disease Severity at 6 Months
Status: TERMINATED
Conditions: Dermatitis, Atopic
Interventions: OTHER: Individual session therapeutic education|OTHER: Phone Call
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hormonal Mechanisms of Sleep Restriction - Axis Study in Older Men and Postmenopausal Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Sleep Restriction
Interventions: DRUG: Ketoconazole Pill (also known as nizoral)|DRUG: Ganirelix|DRUG: Dexamethasone Pill|DRUG: Dexamethasone injection|DRUG: Cosyntropin Injectable Product|DRUG: Recombinant Human Luteinizing Hormone (also known as luveris)|DRUG: Hydrocortisone Injection (also known as solu-cortef)|DRUG: Gonadorelin (also known as Lutrepulse)|DRUG: Corticorelin (also known as Acthrel)|DRUG: Placebo oral tablet|DRUG: Saline Solution|DRUG: Saline solution for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Exercise Training Versus Drug Therapy for Treating Depression in Older Adults
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Supervised Exercise|BEHAVIORAL: Home-Based Exercise|DRUG: Sertraline (Zoloft)|DRUG: Placebo Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: "Comparing Methotrexate Usage Techniques to Prevent Proliferative Vitreoretinopaty After Retinal Detachment Vitrectomy"
Status: RECRUITING
Conditions: Proliferative Vitreoretinopathy
Interventions: DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Phosphatidylserine Improves Cognitive Function in the Elderly
Status: UNKNOWN
Conditions: Aging
Interventions: DIETARY_SUPPLEMENT: Phosphatidylserine|DIETARY_SUPPLEMENT: Bean powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Quality of Life and Utilities Following Surgical Treatment of Stage I-IV Rectal Cancer
Status: RECRUITING
Conditions: Rectal Adenocarcinoma|Stage I Rectal Cancer AJCC v8|Stage II Rectal Cancer AJCC v8|Stage IIA Rectal Cancer AJCC v8|Stage IIB Rectal Cancer AJCC v8|Stage IIC Rectal Cancer AJCC v8|Stage III Rectal Cancer AJCC v8|Stage IIIA Rectal Cancer AJCC v8|Stage IIIB Rectal Cancer AJCC v8|Stage IIIC Rectal Cancer AJCC v8|Stage IV Rectal Cancer AJCC v8|Stage IVA Rectal Cancer AJCC v8|Stage IVB Rectal Cancer AJCC v8|Stage IVC Rectal Cancer AJCC v8
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Salud en Mis Manos - Breast and Cervical Cancer Prevention and Early Detection - Expansion 1
Status: COMPLETED
Conditions: Cervical Cancer|Breast Cancer
Interventions: BEHAVIORAL: Education|BEHAVIORAL: Navigation to clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: TRAUMEEL for Pain After Fracture of Neck of Femur
Status: WITHDRAWN
Conditions: Pain|Fracture of Neck of Femur
Interventions: DRUG: Traumeel S|DRUG: Placebo remedy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Daily Dystonia Practice - A Trial to Investigate NT 201, the Duration of Treatment Effect After One Injection Session and in Long-term Treatment in Cervical Dystonia
Status: COMPLETED
Conditions: Cervical Dystonia
Interventions: DRUG: NT 201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Natalizumab (BG00002, Tysabri®) in Russian Participants With Relapsing Remitting Multiple Sclerosis (RRMS)
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: BIOLOGICAL: BG00002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Drug-Drug Interaction Between Danoprevir Coadministered With Low-Dose Ritonavir and Tenofovir Disoproxil Fumarate or Atazanavir
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: atazanavir|DRUG: danoprevir|DRUG: ritonavir|DRUG: tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD7503 in Healthy Participants
Status: COMPLETED
Conditions: Safety|Tolerability|Pharmacokinetics|Healthy Participants
Interventions: DRUG: AZD7503|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Pathways to Improving Functional Capacity in Older Patients With Chronic Kidney Disease and Cardiovascular Disease
Status: WITHDRAWN
Conditions: Chronic Kidney Disease|Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Fish Oil and Bicarbonate|DIETARY_SUPPLEMENT: Fish Oil and Bicarbonate Placebo|DIETARY_SUPPLEMENT: Fish Oil Placebo and Bicarbonate|DIETARY_SUPPLEMENT: Fish Oil Placebo and Bicarbonate Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Oral High/Low-dose Cepharanthine Compared With Placebo in Non Hospitalized Adults With COVID-19
Status: COMPLETED
Conditions: Asymptomatic COVID-19
Interventions: DRUG: Cepharanthine|DRUG: Placebo|DRUG: Cepharanthine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduction of Spontaneous Prematurity by Antibiotic Treatment (Josamycin)
Status: COMPLETED
Conditions: Prematurity
Interventions: DRUG: Josamycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Hemiarthroplasty Versus Cephalo-medullary Fixation to Treat Unstable Intertrochanteric Femoral Fractures
Status: UNKNOWN
Conditions: Fracture of Femur
Interventions: PROCEDURE: Bipolar hemiarthroplasty , proximal femoral nail
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Noninvasive Ventilation Compared to Salbutamol
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: Bilevel|DRUG: Albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxytocin to Enhance Alcohol Behavioral Couple Therapy (ABCT)
Status: COMPLETED
Conditions: Alcohol Use Disorder|Couples
Interventions: DRUG: Oxytocin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine, Cisplatin, and Amifostine Following Surgery in Treating Patients With Locally Advanced Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer|Drug/Agent Toxicity by Tissue/Organ
Interventions: DRUG: amifostine trihydrate|DRUG: cisplatin|DRUG: gemcitabine hydrochloride|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavior Therapy (CBT) for Children With Functional Gastrointestinal Disorders
Status: COMPLETED
Conditions: Functional Gastrointestinal Disorders (FGID)|FGID According to the Rome III Criteria|Irritable Bowel Syndrome (IBS)|Functional Abdominal Pain|Functional Dyspepsia
Interventions: OTHER: Cognitive behavior therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy and SBRT for Metastatic Head and Neck Carcinomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma|Metastatic Squamous Cell Carcinoma
Interventions: RADIATION: SBRT|DRUG: Durvalumab|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Near Infrared Fluorescence Imaging for Bladder Cancer Detection
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: Hexaminolevulinate HCL|DEVICE: Near Infrared Fluorescence (NIRF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: MR Guided tDCS in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: OTHER: Anodal tDCS|OTHER: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerability and Safety of BDB-001 Injection in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BDB-001 injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab With or Without Lenalidomide in Treating Patients With Previously Untreated Follicular Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: BIOLOGICAL: Rituximab|DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Short-term Parent Mediated Social Training on Developmental Trajectories in Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Younger Sibling of Child With Autism Spectrum Disorder|Signs of Developmental Delay|Signs of Communication Delay|Signs of Social Delay
Interventions: BEHAVIORAL: Infant Achievements|BEHAVIORAL: Caregiver Education (CE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resistance Exercise Plus Vinegar Ingestion on Biomarkers in Healthy Adults
Status: RECRUITING
Conditions: LPS|Mood Disorders|Cognitive Change
Interventions: DIETARY_SUPPLEMENT: Vinegar liquid|DIETARY_SUPPLEMENT: vinegar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Safety and Immunogenicity Study of Eastern Equine Encephalitis (EEE) Vaccine
Status: COMPLETED
Conditions: Eastern Equine Encephalitis
Interventions: BIOLOGICAL: Inactivated, Dried, TSI-GSD 104, EEE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Detection of Colorectal Cancer in Patients With a Positive Fecal Immunochemical Test Using an Electronic Nose Device (AeoNoseTM)
Status: COMPLETED
Conditions: Colorectal Cancer|Polyps of Colon
Interventions: DEVICE: Aeonose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hypofractionated Online Adaptive Radiotherapy of Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: Moderate hypofractionated Radiation Treatment|RADIATION: Ultrafractionated Radiation Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anemia Studies in Chronic Kidney Disease: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor Daprodustat-Dialysis (ASCEND-D)
Status: COMPLETED
Conditions: Anaemia|Aspergillosis, Allergic Bronchopulmonary
Interventions: DRUG: Daprodustat|DRUG: rhEPO|DRUG: Placebo|DRUG: Iron therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OTX-14-001: A Phase 2 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Chronic Allergic Conjunctivitis
Status: COMPLETED
Conditions: Chronic Allergic Conjunctivitis
Interventions: DRUG: Dexamethasone|OTHER: Placebo Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Red Ginseng on Decrement of Body Fat
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Red Ginseng|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Study to Determine the Maximum Tolerate Dose (MTD) of BGT226 in Advanced Solid Tumors in Japan
Status: TERMINATED
Conditions: Cancer|Solid Tumor|Advanced Solid Tumor
Interventions: DRUG: BGT226
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Types of Matrix (Mucograft® and Mucoderm®) Associated With Coronally Advanced Flap
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: CAF|OTHER: MC|OTHER: XDM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic Versus Conventional or Endoscopic Nipple Sparing Mastectomy for Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer Female
Interventions: DEVICE: Robotic assisted nipple sparing mastectomy (R-NSM)|PROCEDURE: conventional nipple sparing mastectomy (C-NSM)|PROCEDURE: Endoscopic assisted nipple sparing mastectomy (E-NSM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of SMART Hall Technique vs. Conventional SS Crown in Primary Molars: A Randomized Clinical Trial
Status: RECRUITING
Conditions: Caries,Dental|Pain|Plaque, Dental|Gingival Bleeding
Interventions: PROCEDURE: SMART Hall Technique or procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simulation-based Training for Nurses and Arteriovenous Fistula Puncture in Chronic Hemodialysis Patients
Status: RECRUITING
Conditions: Nursing Caries|Arteriovenous Fistula|Simulation-based Training
Interventions: OTHER: simulation-based training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neoadjuvant Therapy for the Treatment of Gastroesophageal Junction and Gastric Cancers
Status: NOT_YET_RECRUITING
Conditions: Clinical Stage I Gastric Cancer AJCC v8|Clinical Stage II Gastric Cancer AJCC v8|Clinical Stage IIA Gastric Cancer AJCC v8|Clinical Stage IIB Gastric Cancer AJCC v8|Clinical Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage III Gastric Cancer AJCC v8|Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8|Gastric Adenocarcinoma|Pathologic Stage IB Gastric Cancer AJCC v8|Pathologic Stage IC Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage II Gastric Cancer AJCC v8|Pathologic Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IIA Gastric Cancer AJCC v8|Pathologic Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IIB Gastric Cancer AJCC v8|Pathologic Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage III Gastric Cancer AJCC v8|Pathologic Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IIIA Gastric Cancer AJCC v8|Pathologic Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IIIB Gastric Cancer AJCC v8|Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IIIC Gastric Cancer AJCC v8|Pathologic Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
Interventions: DRUG: Capecitabine|DRUG: Docetaxel|DRUG: Fluorouracil|DRUG: Leucovorin|DRUG: Oxaliplatin|RADIATION: Radiation Therapy|PROCEDURE: Surgical Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT