pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Development of 4D Flow MRI for Risk Stratification of Variceal Bleeding in Cirrhosis
Status: RECRUITING
Conditions: Cirrhosis, Liver|Gastroesophageal Varices
Interventions: OTHER: Ensure Plus®|OTHER: Pre-clinical validation contrast enhanced MRI|OTHER: Clinical validation MRI|OTHER: Pre-clinical validation contrast enhanced MRI + fasting
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fludarabine, Cyclophosphamide, and Thalidomide in Treating Patients With Angioimmunoblastic T-Cell Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: DRUG: cyclophosphamide|DRUG: fludarabine phosphate|DRUG: thalidomide|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study For Evaluating The Value Of A Multi Biomarker Approach In Metastatic GEP NETs
Status: COMPLETED
Conditions: Gastroenteropancreatic Neuroendocrine Tumors
Interventions: OTHER: This is a non-interventional study. Patients will be treated with any intervention deemed appropriate by the patient's physician.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ReActiv8 Implantable Neurostimulation System for Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DEVICE: ReActiv8 Implantable Stimulation System (Patient Appropriate Stimulation)|DEVICE: ReActiv8 Implantable Stimulation System (Low Stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine and Neurofeedback-Training: Effects on Neuroplasticity in Cocaine Addiction
Status: RECRUITING
Conditions: Cocaine Use Disorder|Cocaine Dependence
Interventions: DRUG: Ketamine|DRUG: Placebo|BEHAVIORAL: real-time fMRI neurofeedback training|BEHAVIORAL: sham real-time fMRI neurofeedback training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Cannabidiol for Opioid Withdrawal
Status: COMPLETED
Conditions: Opioid Withdrawal|Opioid Craving|Opioid Use Disorder
Interventions: DRUG: Epidiolex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine in Obturator Nerve Block as an Analgesic in Transurethral Surgeries
Status: COMPLETED
Conditions: Dexmedetomidine
Interventions: DRUG: Dexmedetomidine|DRUG: Bupivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Catheter Directed Therapy in Intermediate Risk Pulmonary Embolism Patients
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Embolism Subacute Massive
Interventions: PROCEDURE: Mechanical embolectomy: by hydromechanical defragmentation by pigtail|DEVICE: Suction embolectomy by the Penumbra Indigo aspiration system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Therapeutic Equivalence and Safety of TRETINOIN CREAM, 0.1% and RLD in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Tretinoin cream 0.1%|DRUG: RETIN-A® Cream|DRUG: Vehicle of the test product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigate a Varnish to Protect From Erosive Toothwear
Status: COMPLETED
Conditions: Tooth Erosion
Interventions: DRUG: Varnishes, Fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: GUT LINK: A Study of a Care Pathway Across Primary and GI Specialty Care
Status: RECRUITING
Conditions: Irritable Bowel Syndrome|GI Disorders
Interventions: BEHAVIORAL: GUT LINK SmartPath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Continuous Positive Airway Pressure (CPAP) in Heart Remodeling by Magnetic Resonance Imaging (MRI)
Status: TERMINATED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: CPAP|DEVICE: No treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Efficacy of TXA127 (Angiotensin 1-7) to Enhance Engraftment in Pediatric Patients Undergoing Single or Double Umbilical Cord Blood Transplantation
Status: WITHDRAWN
Conditions: Cord Blood Transplant|Hematologic Malignancy|Inherited Metabolic Disease
Interventions: DRUG: TXA127
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerance of an Extensively Hydrolyzed Protein Infant Formula Versus a Premature Infant Formula
Status: COMPLETED
Conditions: Feeding Intolerance
Interventions: OTHER: Marketed cow milk-based premature infant formula|OTHER: Marketed extensively hydrolyzed casein infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Enhanced Guidance for Endovascular Repair of Abdominal Aortic Aneurysm
Status: COMPLETED
Conditions: Aortic Aneurysm, Abdominal
Interventions: OTHER: Validation of the new rigid registration software|OTHER: Validation of the new elastic registration software
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Efficacy of Stabilized Chlorine Dioxide Rinse as a Chemical Adjuvant for Treatment of Per-implant Mucositis
Status: COMPLETED
Conditions: Peri-implant Mucositis
Interventions: DRUG: Stabilized chlorine dioxide oral rinse|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ib Trial of the KRAS G12C Inhibitor Adagrasib (MRTX849) in Combination With the PARP Inhibitor Olaparib in Patients With KRAS G12C Mutated Advanced Solid Tumors, With a Focus on Gynecological, Breast, Pancreatic and KEAP1 Mutated Non-small Cell Lung Cancers
Status: RECRUITING
Conditions: Advanced Solid Tumor|Non-small Cell Lung Cancers
Interventions: DRUG: Adagrasib|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study to Measure Vascular Parameters (Ancillary Study of ADEQUATE)
Status: UNKNOWN
Conditions: De Novo Transplant Disease
Interventions: DRUG: Tacrolimus targeted half-dose|DRUG: Tacrolimus targeted plain dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Supporting Transitions to Primary Care Among Under-resourced, Postpartum Women (STEP-UP)
Status: RECRUITING
Conditions: Gestational Diabetes Mellitus|Hypertension in Pregnancy|Dysglycemia
Interventions: BEHAVIORAL: OB Provider Clinical Decision Support (CDS)|BEHAVIORAL: Patient Education (OB Visit)|BEHAVIORAL: Text messaging|BEHAVIORAL: Patient Outreach|BEHAVIORAL: Primary Care Provider Clinical Decision Support (CDS)|BEHAVIORAL: Patient Education (Primary Care Visit)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Immediate Implant Placement Using Immediate Dentoalveolar Restoration Versus Ice Cream Cone Technique With Labial Plate Dehiscence
Status: NOT_YET_RECRUITING
Conditions: Immediate Implant
Interventions: PROCEDURE: Immediate Dentoalveolar Restoration|PROCEDURE: Ice cream cone technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Anti-TNF Monoclonal Antibody in Patients With Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: DRUG: Infliximab 5 mg/kg|DRUG: Infliximab 10 mg/kg|DRUG: Infliximab 20 mg/kg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Epacadostat and Pembrolizumab in Patients With GIST
Status: TERMINATED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Pembrolizumab|DRUG: Epacadostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, and Efficacy of Namilumab in Participants With Active Cardiac Sarcoidosis
Status: TERMINATED
Conditions: Sarcoidosis, Cardiac
Interventions: DRUG: Namilumab|DRUG: Placebo|DRUG: Open label Namilumab|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Lumretuzumab in Combination With Pertuzumab and Paclitaxel in Participants With Metastatic Breast Cancer Expressing Human Epidermal Growth Factor Receptor (HER) 3 and HER2 Protein
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Pertuzumab|DRUG: Lumretuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Cardiorespiratory Fitness on Firefighter Cardiovascular Health Under Exercise Conditions
Status: COMPLETED
Conditions: Cardiovascular Diseases|Post-Exercise Hypotension
Interventions: BEHAVIORAL: GEST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PVP-I Nasal Sprays and SARS-CoV-2 Nasopharyngeal Titers (for COVID-19)
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Povidone-Iodine 2%|DRUG: Povidone-Iodine 0.5%|DRUG: Isotonic saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Small Intestinal Submucosa Graft for Repair of Anterior Urethral Strictures
Status: ENROLLING_BY_INVITATION
Conditions: Urethral Stricture, Male
Interventions: PROCEDURE: Small intestinal submucosa (SIS) graft urethroplasty|PROCEDURE: Autologous oral bucal mucosa graft urethroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FIRM Ablation Versus Pulmonary Vein Isolation for the Treatment of Paroxysmal Atrial Fibrillation (PAF)
Status: TERMINATED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: FIRM-guided RF ablation|PROCEDURE: Conventional RF ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Patient Preference Between Cabazitaxel and Docetaxel in Metastatic Castrate-resistant Prostate Cancer
Status: UNKNOWN
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Taxotere|DRUG: Jevtana
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PREPP: Preventing Postpartum Depression
Status: COMPLETED
Conditions: Postpartum Depression (PPD)
Interventions: BEHAVIORAL: Practical Resources for Effective Postpartum Parenting (PREPP)|BEHAVIORAL: Enhanced Treatment As Usual (ETAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety, Pharmacokinetic and Clinical Activity Study of NUC-7738 in Patients With Advanced Solid Tumours and Lymphoma
Status: RECRUITING
Conditions: Advanced Cancer|Lymphoma|Solid Tumor
Interventions: DRUG: NUC-7738|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BROKEN-SWEDEHEART- Optimized Pharmacological Treatment for Broken Heart (Takotsubo) Syndrome.
Status: RECRUITING
Conditions: Takotsubo Syndrome
Interventions: DRUG: Adenosine|DRUG: Dipyridamole 200 mg|DRUG: Apixaban 5 mg Oral Tablet|OTHER: Care as recommended by the Taskforce on Takotsubo Syndrome of the Heart Failure Association of the European Society of Cardiology for takotsubo syndrome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Partially Hydrolyzed Guar Gum (PHGG) for Amelioration of Chronic Obstructive Pulmonary Disease (COPD)
Status: UNKNOWN
Conditions: COPD|Microbial Colonization|Respiratory Tract Disease
Interventions: DIETARY_SUPPLEMENT: Partially Hydrolyzed Guar Gum (PHGG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing CVD Risk in Caregivers: A Brief Behavioral Activation Intervention
Status: COMPLETED
Conditions: Depressive Symptoms|Inflammation
Interventions: BEHAVIORAL: Pleasant Events Program (PEP)|BEHAVIORAL: Information Support (IS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electrophysiological Effects of Potential QT Prolonging Drugs
Status: COMPLETED
Conditions: Drug-induced QT Prolongation|Pharmacokinetics|Pharmacodynamics
Interventions: DRUG: Clarithromycin|DRUG: Pimozide|DRUG: Placebo (Part 1)|DRUG: Moxifloxacin|DRUG: Cobicistat|DRUG: Moxifloxacin and Cobicistat|DRUG: Placebo (Part 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: 18F-DTBZ PET and Multi-modal MRI in the Patients With Vascular Parkinsonism
Status: COMPLETED
Conditions: Vascular Parkinsonism
Interventions: DRUG: 18F-DTBZ
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Anterior Approach of the Combined Lumbar and Sacral Plexuses Block for Analgesia of Lower Limb Surgeries
Status: RECRUITING
Conditions: Lower Limb Fracture
Interventions: PROCEDURE: one point combined Lumbar and sacral plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: AMG 386 (Trebananib) in Ovarian Cancer (TRINOVA-2)
Status: TERMINATED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cancer
Interventions: DRUG: AMG386 plus PLD|DRUG: Placebo plus PLD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Symptoms After Stent Placement for Urinary Tract Obstruction
Status: COMPLETED
Conditions: Ureteral Obstruction
Interventions: DRUG: Tamsulosin|DRUG: Tolterodine ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: In-hospital Versus After-discharge Complete Revascularization
Status: COMPLETED
Conditions: STEMI - ST Elevation Myocardial Infarction|Multivessel Coronary Artery Disease
Interventions: OTHER: In-hospital nonculprit-lesions percutaneous coronary intervention (PCI)|OTHER: After-discharge nonculprit-lesions percutaneous coronary intervention (PCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics of Glasdegib
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Glasdegib 100 mg single oral dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Testicular Proteins for Sperm Retrieval Prediction Protein1, Testis-Expressed Gene 101, and Lectin Galactoside-binding Protein in Predicting Surgical Sperm Retrieval in Men With Non-Obstructive Azoospermia
Status: RECRUITING
Conditions: Non-obstructive Azoospermia
Interventions: DIAGNOSTIC_TEST: Semen analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluate Anti-adhesive Effect and Safety of a Mixed Solid of Poloxamer, Gelatin and Chitosan(Mediclore®)
Status: UNKNOWN
Conditions: Gynecologic Disease
Interventions: DEVICE: Mediclore|DEVICE: Adept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Standardized Meditation Technique "Body-scan", in the Management of Anxiety in Hospitalized Parkinsonian Patients
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: OTHER: body-scan meditation|DIAGNOSTIC_TEST: Psychological evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 2 Midostaurin in Aggressive Systemic Mastocytosis and Mast Cell Leukemia
Status: COMPLETED
Conditions: Systemic Mastocytosis, Aggressive (ASM)|Leukemia, Mast Cell|Hematological Non-mast Cell Lineage Disease (AHNMD)
Interventions: DRUG: Midostaurin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adding Guided Self-Help Group Therapy to the Alli Weight Loss Program in Treating Binge Eating Disorder
Status: COMPLETED
Conditions: Overweight|Eating Disorders
Interventions: BEHAVIORAL: Emotion regulation group therapy|DRUG: Orlistat/alli program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Dexmedetomidine and Remifentanil Infusion During CABG
Status: COMPLETED
Conditions: Coronary Artery Bypass Graft|Hypokalemia|Cardiac Arrhythmia|Dexmedetomidine|Remifentanil
Interventions: DRUG: Dexmedetomidine infusion|DRUG: Remifentanil infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Intervention for Monitoring of Salt Intake in Hypertensive Patients
Status: UNKNOWN
Conditions: Hypertension|Salt; Excess
Interventions: BEHAVIORAL: Education|BEHAVIORAL: Reformulation|BEHAVIORAL: Environmental change|DEVICE: Salt meter|BEHAVIORAL: standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy Of Valdecoxib In Patients Following Bunion Surgery
Status: COMPLETED
Conditions: Pain, Post-surgical
Interventions: DRUG: valdecoxib|DRUG: valdecoxib/placebo|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab, Fludarabine, and Cyclophosphamide or Observation Alone in Treating Patients With Stage 0, Stage I, or Stage II Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HEAlth Dialogues for Patients With Mental Illness in Primary Care
Status: RECRUITING
Conditions: Mental Illness|Stress|Fatigue|Sleep Disorder|Depression|Diabetes|Myocardial Disease|Stroke|Death
Interventions: BEHAVIORAL: health dialogue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Converting From Ropinirole Immediate Release (IR) To Ropinirole Controlled-Release for RLS (Restless Legs Syndrome)
Status: COMPLETED
Conditions: Restless Legs Syndrome|Restless Legs Syndrome (RLS)
Interventions: DRUG: Ropinirole IR 1 mg|DRUG: Ropinirole IR 2 mg|DRUG: Ropinirole IR 1 mg Placebo|DRUG: Ropinirole IR 2 mg Placebo|DRUG: Ropinirole CR 2 mg|DRUG: Ropinirole CR 3 mg|DRUG: Ropinirole CR 2 mg Placebo|DRUG: Ropinirole CR 3 mg Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: BOOST: Breastfeeding Onset and Onward With Support Tools
Status: ACTIVE_NOT_RECRUITING
Conditions: Breastfeeding Duration
Interventions: BEHAVIORAL: WIC support + home-based individual support + Breastfeeding Incentives (SC+BFI)|BEHAVIORAL: WIC support + home-based individual support (SC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TAK-385 Phase I Absorption, Distribution, Metabolism, Excretion and Absolute Bioavailability Study
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: [14C]-TAK-385 Oral Solution|DRUG: TAK-385 Tablets|DRUG: [14C]-TAK-385 Solution for Intravenous Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: "EspaiJove.Net"- a School-based Intervention Program to Promote Mental Health in Adolescent Population
Status: COMPLETED
Conditions: Mental Health|Stigma, Social
Interventions: OTHER: "EspaiJove.net" mental health literacy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Increasing Risk Perception of Physical Activity Using Patient-targeted Feedback.
Status: COMPLETED
Conditions: Hypertension|Coronary Disease|Cardiac Diseases
Interventions: BEHAVIORAL: Patient-targeted individual physical-activity-feedback|DEVICE: Pedometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vvax001 Cancer Vaccine in Premalignant Cervical Lesions - Phase II
Status: RECRUITING
Conditions: CIN3|Cervical Intraepithelial Neoplasia|Cervical Intraepithelial Neoplasia Grade 3|HPV 16 Infection
Interventions: BIOLOGICAL: Vvax001 therapeutic cancer vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Market Study of Comprehensive Reverse Augmented Glenoid and Mini Humeral Tray in Total Shoulder Arthroplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Arthropathy of Shoulder Region|Grossly Deficient Rotator Cuff|Osteoarthritis of the Shoulder|Rheumatoid Arthritis Without Humeral Metaphyseal Defects|Post-Traumatic Arthritis
Interventions: DEVICE: Comprehensive Reverse Porous Augmented Glenoid|DEVICE: Comprehensive Mini Humeral Tray
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real Life Experience With Caduet In Patients With Cardiovascular Risk Factors
Status: TERMINATED
Conditions: Hypertension and Cardiovascular Risk Factors
Interventions: DRUG: CADUET (AMLODIPINE 5 mg/ATORVASTATIN 10 mg or 20 mg)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Peri-implant Mucositis on Incongruous Dental Prostheses Versus Congruous
Status: RECRUITING
Conditions: Bleeding of Subgingival Space
Interventions: OTHER: Changes in Probing Depth to non-surgical periodontal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study on Dialysis Modalities for End-stage Chronic Renal Failure Patients With Heparin-induced Thrombocytopenia
Status: NOT_YET_RECRUITING
Conditions: Dialysis; Complications|Heparin-induced Thrombocytopenia|Chronic Renal Failure
Interventions: PROCEDURE: Hydrolink NV membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cohera TissuGlu® Surgical Adhesive in the Management of Wound Drainage
Status: COMPLETED
Conditions: Abdominoplasty
Interventions: DEVICE: TissuGlu Surgical Adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Effectiveness of Amniotic Membrane and Duoderm Dressings in Pediatric Burns
Status: COMPLETED
Conditions: Burns
Interventions: COMBINATION_PRODUCT: amniotic membrane|COMBINATION_PRODUCT: duoderm dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating SKI-606 (Bosutinib) In Subjects With Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Neoplasm Metastasis
Interventions: DRUG: SKI-606 (Bosutinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sirolimus vs Corticosteroids in Treatment of Thyroid Eye Disease
Status: RECRUITING
Conditions: Thyroid-Associated Ophthalmopathy
Interventions: DRUG: Sirolimus 1 mg Oral Tablet|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Intravitreal Aflibercept Injections on Capillary Non-Perfusion
Status: COMPLETED
Conditions: Central Retinal Vein Occlusion|Proliferative Diabetic Retinopathy
Interventions: DRUG: Intravitreal Aflibercept Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics on Infantile Colic Symptoms
Status: RECRUITING
Conditions: Infantile Colic
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PDR001 in Combination With Platinum-doublet Chemotherapy and Other Immunology Agents in PD-L1 Unselected, Metastatic NSCLC Patients
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: PDR001|DRUG: Cisplatin|DRUG: Gemcitabine|DRUG: Pemetrexed|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Canakinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Early Palliative Care Intervention for High-Risk Patients in the Intensive Care Unit-A Pilot Study
Status: UNKNOWN
Conditions: End-of-life Care|Palliative Care|Intensive Care Unit
Interventions: OTHER: Pro-active palliative care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bone Marrow Transplantation in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: methotrexate|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: in vitro-treated bone marrow transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: 3D Printing to Improve Nasal Irrigation Outcome
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps|Chronic Rhinosinusitis Without Nasal Polyps
Interventions: OTHER: Irrigation head position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Muscle O2 Saturation and Hemoglobin Levels During Rehabilitation From Arthroscopic Surgery
Status: RECRUITING
Conditions: ACL Injury|Hip Injuries
Interventions: PROCEDURE: Physical Therapy|PROCEDURE: Monitored Work-out|DEVICE: Moxy Oxygen Sensor Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Small Phlebotomy Tubes in Reducing Blood Transfusions in Adult Medical Intensive Care Unit and Intermediate Care Unit Patients With Anemia
Status: RECRUITING
Conditions: Anemia
Interventions: DEVICE: Small Phlebotomy Tube Group|DEVICE: Standard Phlebotomy Tube Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Analysis of Volatile Organic Compounds by Electronic Noses in Hospitalised Patients for an Infection by SARS-COV-2 (COVID-19)
Status: COMPLETED
Conditions: COVID-19
Interventions: DEVICE: Volatile Organic Compounds analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Analgesic Use During the Therapy of Iatrogenic Pneumothorax Using Pleuralvent™ and Chest Tube
Status: RECRUITING
Conditions: Pneumothorax
Interventions: DEVICE: Pleuralvent™|PROCEDURE: Chest tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sodium Pertechnetate (99Tc) Injection Generator: 99mTc From Neutron-activation 99Mo v 99mTc From Fission 99Mo
Status: TERMINATED
Conditions: Cancer of Bone
Interventions: DRUG: 99mTc MDP Injection:neutron-bombardment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Studying Movement Control in Parkinson's Disease Using Closed Loop Deep Brain Stimulation
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: PROCEDURE: Deep Brain Stimulation applied through custom built external stimulator (Little et al., 2013, 2015)|PROCEDURE: closed-loop Deep Brain Stimulation applied through custom built external stimulator (Little et al., 2013, 2015)|PROCEDURE: Deep Brain Stimulation off|DEVICE: local field potentials and electroencephalography recordings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Durability of Double-gloving With Biogel® Surgical Gloves When Used by Clinicians/Surgeons
Status: COMPLETED
Conditions: Gloves, Surgical
Interventions: DEVICE: Biogel|DEVICE: Ansell|DEVICE: Cardinal|DEVICE: Medline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Randomized Phase II Study of Two Doses of Interferon Alfa-2a (IFN Alfa-2a) in Combination With Zidovudine (AZT) and Dideoxycytidine (ddC) Versus AZT and ddC Only in Patients With HIV Infection and Less Than 400 CD4 Cells/mm3
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Interferon alfa-2a|DRUG: Zidovudine|DRUG: Zalcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Treatment of Relapsed or Refractory Diffuse Large B Cell Lymphoma With Ociperlimab (BGB A1217) in Combination With Tislelizumab (BGB A317) or Rituximab
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed Diffuse Large B-cell Lymphoma|Refractory Diffuse Large B-cell Lymphoma
Interventions: DRUG: Ociperlimab|DRUG: Tislelizumab|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Large-Bore Mechanic Thrombectomy for the Treatment of Symptomatic Portomesenteric Vein Thrombosis
Status: NOT_YET_RECRUITING
Conditions: Thrombosis|Thrombectomy|Portal Vein
Interventions: DEVICE: Inari Triever Aspiration Catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mixed Reality Technique Combined With 3D Printing Navigational Template for Localizing Pulmonary Nodules
Status: UNKNOWN
Conditions: Video-assisted Thoracic Surgery|Lung Cancer|Pulmonary Nodule, Solitary|Pulmonary Nodule, Multiple
Interventions: DEVICE: Mixed Reality+ 3D printing guided localization|DEVICE: Computerized Tomography guided localization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlled Level EVERolimus in Acute Coronary Syndromes
Status: COMPLETED
Conditions: Acute Coronary Syndromes
Interventions: DRUG: Everolimus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pivotal RCT to Test Safety and Efficacy of Digital Therapeutics 'ANZEILAX' for Managing Generalized Anxiety Disorder
Status: RECRUITING
Conditions: Generalized Anxiety Disorder
Interventions: DEVICE: Software as a Medical device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Two Different Ventilation Strategies on Lung Ventilation: An Ultrasonographic Evaluation.
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: OTHER: Pressure Controlled Ventilation|OTHER: Volume Controlled Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Ohio Colorectal Cancer Prevention Initiative
Status: COMPLETED
Conditions: Lynch Syndrome|Colorectal Cancer
Interventions: GENETIC: LS tumor screening|GENETIC: Genetic testing|BEHAVIORAL: Genetic Counseling|OTHER: Biorepository|BEHAVIORAL: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Serratus Block Versus Paravertebral Block for Post Thoracotomy Pain Relief
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: PROCEDURE: Standard anesthesia in addition to serratus plane block|PROCEDURE: Standard anesthesia in addition to para-vertebral block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Value of Macrophage-Colony Stimulating Factor as a New Marker of Bone Lesions in Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: blood samples|BIOLOGICAL: Bone marow samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Radiation Therapy With or Without Thalidomide in Treating Patients With Brain Metastases
Status: COMPLETED
Conditions: Tumors Metastatic to Brain
Interventions: RADIATION: radiation therapy|DRUG: thalidomide|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Randomized, Placebo-Controlled, Crossover Study of Soy Protein Isolate for Hereditary Hemorrhagic Telangiectasia
Status: COMPLETED
Conditions: Hereditary Hemorrhagic Telangiectasia
Interventions: DRUG: soy protein isolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Abiraterone Acetate in Subjects With Metastatic Castration Resistant Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Castration Resistant Prostate Cancer
Interventions: DRUG: Abiraterone Acetate|DRUG: Placebo|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing ctDNA-based MRD Assessment in DLBCL, MCL, and FL Patients Undergoing CAR Therapy
Status: RECRUITING
Conditions: Follicular Lymphoma|Diffuse Large B Cell Lymphoma|Mantle Cell Lymphoma
Interventions: DEVICE: ClonoSEQ
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Investigate the Pharmacokinetics and ECG Effects of Linaprazan Glurate
Status: RECRUITING
Conditions: Pharmacokinetics|Cardiodynamic ECG|Safety, and Tolerability|GERD
Interventions: DRUG: Linaprazan glurate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: DS-3201b for Acute Myelogenous Leukemia (AML) or Acute Lymphocytic Leukemia (ALL)
Status: TERMINATED
Conditions: Leukemia, Myeloid, Acute|Leukemia, Lymphocytic, Acute
Interventions: DRUG: DS-3201b
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of the LVIS™ (Low-profile Visualized Intraluminal Support)Device
Status: COMPLETED
Conditions: Intracranial Aneurysms
Interventions: DEVICE: Low profile Visualized Intraluminal Device (LVIS and LVIS Jr.)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bariatric Embolization of Arteries for the Treatment of Nonalcoholic Steatohepatitis
Status: NOT_YET_RECRUITING
Conditions: Obesity|Weight Loss|Body Weight|Nonalcoholic Steatohepatitis|Nonalcoholic Fatty Liver Disease|NAFLD
Interventions: DEVICE: Embospheres Microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrical Impedance Tomography & Selective Stimulation of Vagus Nerve
Status: RECRUITING
Conditions: Vagus Nerve Diseases|Epilepsy|Vagus Nerve Autonomic Disorder
Interventions: DEVICE: Nerve cuff electrodes for spatially selective vagus nerve stimulation and electrical impedance tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combined Social Worker and Pharmacist Transitional Care Program
Status: COMPLETED
Conditions: Patient Admission|Patient Discharge
Interventions: BEHAVIORAL: Combined Social Worker and Pharmacist Program|BEHAVIORAL: No Intervention: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Antioxidant Effects of Pomegranate Juice Versus Placebo in Adults With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Pomegranate Juice|DIETARY_SUPPLEMENT: Placebo Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Remote Photoplethysmography to Assist Vital Signs Measure in Pediatrics
Status: NOT_YET_RECRUITING
Conditions: Using Remote Photoplethysmography for Physiological Parameters
Interventions: DEVICE: Remote photoplethysmography for physiological parameters
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial Of Misoprostol And Dinoprostone Vaginal Pessaries for Cervical Priming (TROMAD Study)
Status: COMPLETED
Conditions: Induction of Labour
Interventions: DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Insulin Glargine/Lixisenatide Fixed Ratio Combination in Patients With Type 2 Diabetes Insufficiently Controlled With Oral Antidiabetic Drug(s)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin glargine/Lixisenatide (HOE901/AVE0010)|DRUG: Insulin glargine (HOE901)|DRUG: Lixisenatide (AVE0010)|DRUG: Metformin|DRUG: SGLT2 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wearable Devices in the Recovery Phase of Acute Exacerbations of COPD (AECOPDs)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Chronic Obstructive Pulmonary Disease Exacerbation
Interventions: DEVICE: Biometric wearable devices
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dual Hypothermic Oxygenated Machine Perfusion in Liver Transplantation Using Allografts From Donors After Brain Death
Status: UNKNOWN
Conditions: Liver Cirrhosis|Liver Tumor|Liver Transplant Failure and Rejection
Interventions: PROCEDURE: Hypothermic oxygenated machine perfusion|PROCEDURE: Simple cold storage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CLearing Alzheimer's Disease Molecular Pathology Without Medications
Status: UNKNOWN
Conditions: Alzheimer Disease|Amyloid Plaque|Amyloidosis
Interventions: OTHER: 40 Hz multi-sensory (auditory + visual) stimulation and cognitive training|OTHER: Cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-PP) for Patients With Advanced Cancer.
Status: COMPLETED
Conditions: Ovarian|Melanoma|Renal|Prostate|Colorectal|Endometrial Carcinoma|Cervical Carcinoma|Testicular Cancer|Thyroid Cancer|Small Cell Lung Carcinoma|Mesothelioma|Breast Carcinoma|Esophageal Carcinoma|Gastric Cancer|Pancreatic Carcinoma|Neuroendocrine Cancer|Liver Cancer|Gallbladder Cancer|Biliary Tract Cancer|Anal Carcinoma|Bone Sarcomas|Soft Tissue Sarcomas|Carcinoma of Unknown Origin, Primary
Interventions: BIOLOGICAL: PSMA/PRAME|BIOLOGICAL: PSMA/PRAME
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Cryoablation and Radiofrequency Ablation in the Treatment of Supraventricular Tachycardia
Status: UNKNOWN
Conditions: Supraventricular Tachycardia|Atrioventricular Nodal Reentrant Tachycardia
Interventions: PROCEDURE: cryoablation|PROCEDURE: radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ovulation Incidence in Oral Contraceptive Users
Status: SUSPENDED
Conditions: Contraception|Ovulation
Interventions: DRUG: Ethinyl Estradiol, Norethindrone acetate, ferrous fumarate|DRUG: Norethindrone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Physician Optimised Post-partum Hypertension Treatment Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Pre-Eclampsia|Gestational Hypertension
Interventions: DEVICE: OMRON Evolv® blood pressure monitor (Blue-tooth® enabled) & Proprietary Smartphone POP-HT app®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Panitumumab (Vectibix®) in Cutaneous Squamous Cell Carcinoma (SCC)
Status: UNKNOWN
Conditions: Carcinoma, Squamous Cell
Interventions: DRUG: infusions of Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repair of Infective Wound Associated With Nerve Defect in the Finger Using A Bipedicled Nerve Flap
Status: COMPLETED
Conditions: Infection Wound|Disruption of Nerve Repair
Interventions: DEVICE: Nerve flap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gefitinib, Docetaxel, and Radiation Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: docetaxel|DRUG: gefitinib|OTHER: laboratory biomarker analysis|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Laser Photobiomodulation Therapy in Reducing Child Pain During Local Anesthesia Injection
Status: RECRUITING
Conditions: Local Anesthesia Injection Pain
Interventions: DEVICE: Photobiomodulation|DRUG: Benzocaine Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Carmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Retifanlimab|DRUG: Temozolomide|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total-Body Irradiation, Fludarabine, and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: mycophenolate mofetil|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT