pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: KeraStat Skin Therapy in Treating Radiation Dermatitis in Patients With Newly Diagnosed Stage 0-IIIA Breast Cancer
Status: WITHDRAWN
Conditions: Ductal Breast Carcinoma in Situ|Skin Reactions Secondary to Radiation Therapy|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage IIIA Breast Cancer
Interventions: PROCEDURE: dermatologic complications management/prevention|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase II Study of 610 in Participants With Severe Eosinophilic Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: DRUG: 610 100mg|DRUG: 610 300mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stent vs. Indomethacin for Preventing Post-ERCP Pancreatitis
Status: COMPLETED
Conditions: Post-ERCP Pancreatitis
Interventions: OTHER: Indomethacin 100 mg rectally immediately after ERCP, NO prophylactic pancreatic stent placement|OTHER: Indomethacin 100 mg rectally immediately after ERCP AND prophylactic pancreatic stent placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of EF5 to Measure the Oxygen Level in Tumor Cells of Patients Undergoing Surgery or Biopsy for Newly Diagnosed Supratentorial Malignant Glioma
Status: TERMINATED
Conditions: Adult Anaplastic Astrocytoma|Adult Anaplastic Ependymoma|Adult Anaplastic Oligodendroglioma|Adult Diffuse Astrocytoma|Adult Ependymoma|Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Adult Mixed Glioma|Adult Myxopapillary Ependymoma|Adult Oligodendroglioma|Adult Pilocytic Astrocytoma|Adult Pineal Gland Astrocytoma|Adult Subependymoma
Interventions: DRUG: etanidazole|PROCEDURE: conventional surgery|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Transplantation of Autologous Oral Mucosal Epithelial Stem Cell Sheet for Treating Limbal Stem Cell Deficiency Disease
Status: UNKNOWN
Conditions: Limbal Stem Cell Deficiency
Interventions: OTHER: cultured autologous oral mucosal epithelial cell sheet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Inactivated SARS-CoV-2 Vaccine in Immune-related Myopathy (Myasthenia Gravis and Inflammatory Myopathy) Patients ：a Prospective Observational Study
Status: UNKNOWN
Conditions: Covid19|Myopathy
Interventions: OTHER: no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of ST-100 (Vezocolmitide) Ophthalmic Solution 60 μg/ml Ophthalmic Solution in Subjects Diagnosed With Dry Eye Disease (DED)
Status: RECRUITING
Conditions: Dry Eye Disease
Interventions: DRUG: ST-100 (vezocolmitide)|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Low Dose Oral Interferon Alpha in Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Respiratory Tract Diseases|Lung Diseases|Lung Diseases, Interstitial|Pulmonary Fibrosis
Interventions: DRUG: Interferon alpha oral lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab (MK-3475) in Patients With Recurrent Malignant Glioma With a Hypermutator Phenotype
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioma|Recurrent Malignant Glioma
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety & Efficacy Study of Treatment With AP1189 in Rheumatoid Arthritis Patients naïve to DMARD Treatment
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: 100 mg AP1189|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CArotenoid in hypoChOlesterolemia
Status: RECRUITING
Conditions: Primary Intestinal Hypocholesterolemia|Abetalipoproteinemia|Chylomicron Retention Disease
Interventions: BIOLOGICAL: Characterization of carotenoid status and plasma levels of oxidative stress markers in patients (case group only)|OTHER: Characterization, evaluation and comparison of macular pigment density
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Single-arm, Phase Ⅱ Clinical Trial of Anlotinib Hydrochloride Combined With Irinotecan or Docetaxel for Second Line Treatment of Nonsensitive Relapsed Small-cell Lung Cancer
Status: RECRUITING
Conditions: Relapsed Small Cell Lung Cancer|Anlotinib
Interventions: DRUG: anlotinib hydrochloride combined with irinotecan or docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Outcomes in Cardiac Surgery Patients Who Receive Sugammadex vs. Placebo
Status: RECRUITING
Conditions: Surgery
Interventions: DRUG: Sugammadex|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: XCHT for Irinotecan-Induced Gut Toxicities (Randomized Controlled Trial)
Status: RECRUITING
Conditions: Xiao Chai Hu Tang|Irinotecan-induced Diarrhea
Interventions: DRUG: Xiao Chai Hu Tang (XCHT)|DRUG: Placebo|DRUG: Irinotecan regimen|OTHER: Raloxifene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Itraconazole on the Pharmacokinetics of Bardoxolone Methyl in Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Bardoxolone methyl capsules 10 mg|DRUG: Itraconazole capsules 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET Imaging of Peripheral Benzodiazepine Receptors in Patients With Neurocysticercosis Using [F-18]FB
Status: COMPLETED
Conditions: Neurocysticercosis|Healthy
Interventions: DRUG: [F-18]FBR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Relacorilant on the Pharmacokinetics of the Sensitive P-glycoprotein Substrate Dabigatran Etexilate in Healthy Participants
Status: COMPLETED
Conditions: Cushing Syndrome|Neoplasms
Interventions: DRUG: Dabigatran Etexilate|DRUG: Relacorilant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preparing Family Caregivers to Make Medical Decisions for Their Loved Ones
Status: COMPLETED
Conditions: Neoplasms|Heart Failure|Kidney Diseases|Lung Diseases
Interventions: BEHAVIORAL: Making Your Wishes Known|BEHAVIORAL: Standard advance care planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Macrolides on Asthma Control
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adoptive Transfer of iNKT Cells for Treating Patients With Relapsed/Advanced HCC
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: iNKT cells|DRUG: IL-2|DRUG: Tegafur
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electronic Spectacles Versus Low Dose Atropine in Young Myopes
Status: NOT_YET_RECRUITING
Conditions: Myopia
Interventions: DEVICE: eSpectacle Clinical prototype (CP1) device|DRUG: 0.01% atropine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aspirin Discontinuation in High-Risk Pregnant Women of Preeclampsia
Status: RECRUITING
Conditions: Preeclampsia|Perinatal Haemorrhage
Interventions: DRUG: aspirin discontinuation|DRUG: aspirin continuation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Posterior Scleral Reinforcement on Controlling Myopia in Adults With High Myopia
Status: UNKNOWN
Conditions: High Myopia|Posterior Scleral Reinforcement|Adults|Axial Elongation|Myopia Progression
Interventions: PROCEDURE: Posterior scleral reinforcement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing the Primary Prevention of Type-2 Diabetes in Primary Health Care
Status: COMPLETED
Conditions: Interprofessional Relations|Primary Health Care/Organization & Administration|Diabetes Mellitus, Type 2/Prevention & Control|Primary Prevention/Methods|Risk Reduction Behavior|Randomized Controlled Trial|Life Style
Interventions: BEHAVIORAL: Healthy lifestyle prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cutaneous Microcirculation After Extracorporeal Shock Wave Therapy
Status: COMPLETED
Conditions: Burn Injury|Acute Wound|Chronic Wound|Burn Scar|Flap Disorder
Interventions: DEVICE: Extracorporeal Shock Wave Therapy (Device Name: PiezoWave)|DEVICE: Repetitive Extracorporeal Shock Wave Therapy (Device Name: PiezoWave)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study on the Effects of Inhalation of Volatile Oil of Cang-Ai Via the Nose on Patients With Depression
Status: NOT_YET_RECRUITING
Conditions: Depressive Disorder|Mental Disorder in Adolescence
Interventions: DRUG: Volatile Oil of Cang-Ai|DRUG: Bergamot essential oils
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study With Blinatumomab in Patients With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (ALL)
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: Blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted Extinction of Drug Cues During Sleep - Olfactory Cue Reactivity Task
Status: COMPLETED
Conditions: Heavy Drinking
Interventions: OTHER: Non-Alcoholic Odour|OTHER: Alcoholic Odour|OTHER: Non-Alcoholic Images|OTHER: Alcoholic Images
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Continuous Positive Airway Pressure Treatment of Obstructive Sleep Apnea to Prevent Cardiovascular Disease
Status: UNKNOWN
Conditions: Sleep Apnea|Cardiovascular Disease
Interventions: DEVICE: Continuous Positive Airway Pressure (CPAP)|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Anti PD-1 Antibody With Radiation Therapy in Patients With HER2-negative Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Cohort A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics Study of New Formulation of Bimatoprost in Patients With Alopecia
Status: COMPLETED
Conditions: Alopecia|Alopecia, Androgenetic|Baldness
Interventions: DRUG: bimatoprost Formulation A|DRUG: bimatoprost Formulation B|DRUG: bimatoprost Formulation C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Vacuum Assisted Closure (VAC) Device in Postoperative Management of Pelvic and Acetabular Fractures
Status: COMPLETED
Conditions: Pelvic Fractures|Acetabular Fractures|Hip Fractures
Interventions: DEVICE: VAC device|OTHER: Gauze dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Eteplirsen to Treat Early Stage Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy (DMD)
Interventions: DRUG: eteplirsen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simultaneous Dental Implant in Free Vascularized Bone Flaps for Jaw Reconstruction
Status: UNKNOWN
Conditions: Mandibular Reconstruction|Dental Implant|Free Tissue Flaps|Jaw Neoplasms
Interventions: PROCEDURE: Simultaneous dental implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ISM6331 in Participants With Advanced/Metastatic Malignant Mesothelioma or Other Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Malignant Mesothelioma|Metastatic Malignant Solid Tumor|Advanced Solid Tumor
Interventions: DRUG: ISM6331
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Verbal Intelligent Tutor Instruction in Neurosurgical Simulation
Status: NOT_YET_RECRUITING
Conditions: Surgical Education
Interventions: BEHAVIORAL: Experimental Group - Verbal expert instructor feedback in AI's words|BEHAVIORAL: Experimental Group - Verbal expert instructor feedback in expert's own words
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effects of Dexmedetomidine on Postoperative Renal Function in Valvular Heart Surgery
Status: UNKNOWN
Conditions: Acute Kidney Injury
Interventions: DRUG: dexmedetomidine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Rocuronium Plus Sugammadex Versus Succinylcholine Alone in Participants Undergoing Short Surgical Procedures (19.4.319)(P05700 AM2)(COMPLETED)
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: DRUG: rocuronium|DRUG: sugammadex|DRUG: succinylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Family Meal Duration and Children's Eating Behavior
Status: COMPLETED
Conditions: Feeding Behavior|Eating|Child Behavior|Family Relations
Interventions: BEHAVIORAL: Longer meal duration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: CRLX101 in Combination With Bevacizumab for Recurrent Ovarian/Tubal/Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: DRUG: CRLX101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study to Observe & Describe Clinical Outcomes of Alglucosidase Alfa Treatment in Patients ≤6 Months of Age With Infantile-onset Pompe Disease (IOPD)
Status: RECRUITING
Conditions: Glycogen Storage Disease Type II
Interventions: DRUG: Alglucosidase alfa GZ419829
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Clinical Efficacy of Resveratrol in Improving Metabolic and Skeletal Muscle Function in Patients With Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure Chronic
Interventions: DRUG: Resveratrol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Study of IMMU-132 Alone or in Combination With Carboplatin in Patients With Triple-Negative Breast Cancer
Status: WITHDRAWN
Conditions: Triple-negative Breast Cancer
Interventions: DRUG: IMMU-132 infusion is administered to participants in one arm for the study|DRUG: IMMU-132 plus Carboplatin infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Outcomes Between the Use of Silverlon® Dressing and AQUACEL® AG Dressing Post Cardiac Device Implant
Status: COMPLETED
Conditions: Infections|Wounds and Injuries
Interventions: DEVICE: Silverlon®|DEVICE: AQUACEL® AG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Three-Group Study to Examine the Efficacy of the Air up® Drinking System at Improving Hydration and Associated Health Outcomes
Status: COMPLETED
Conditions: Water Intake
Interventions: DIETARY_SUPPLEMENT: Air Up® Peach Pod|DIETARY_SUPPLEMENT: Air Up® Orangeade Pod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Systemic Probiotics in the Periodontal Treatment
Status: UNKNOWN
Conditions: Periodontitis
Interventions: PROCEDURE: Scaling and root planing|DRUG: Metronidazole and Amoxicillin placebos|DRUG: Metronidazole|DRUG: Amoxicillin|DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Probiotic placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Inhaled Carbon Monoxide to Treat Acute Respiratory Distress Syndrome (ARDS)
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome (ARDS)
Interventions: DRUG: Inhaled Carbon Monoxide at 100ppm (4 participants)|DRUG: Placebo for Inhaled Carbon Monoxide at 100ppm (2 participants)|DRUG: Inhaled Carbon Monoxide at 200ppm (4 participants)|DRUG: Placebo for Inhaled Carbon Monoxide at 200ppm (2 participants)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: TC-5619 as Augmentation Therapy to Improve Cognition in Outpatients With Cognitive Dysfunction in Schizophrenia
Status: COMPLETED
Conditions: Cognitive Dysfunction|Schizophrenia
Interventions: DRUG: TC-5619|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of UP-CAT With and Without Visual Feedback in Children With CP
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: upper limb children action-observation training (UPCAT)|OTHER: upper limb children action-observation training (UP-CAT) with visual feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Atorvastatin in Pelvic Pain Relief in Women With Endometriosis
Status: UNKNOWN
Conditions: Endometriosis|Pain
Interventions: DRUG: oral contraceptive (Mercilon)|DRUG: atorvastatin + oral contraceptive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictive Factors of Good Pulmonary Penetration of Antibiotics : AntiBiotics Dosage in Broncho-Alveolar Lavage
Status: COMPLETED
Conditions: Antibiotics|Pneumonia
Interventions: BIOLOGICAL: measure of intra-alveolar antibiotic concentration in µg/ml|PROCEDURE: broncho-alveolar lavage (BAL)|BIOLOGICAL: blood test to measure plasmatic antibiotic concentration in µg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Evaluation of the Safety and Efficacy of LIPO-102 for the Reduction of Subcutaneous Abdominal Adiposity
Status: COMPLETED
Conditions: Subcutaneous Abdominal Adiposity
Interventions: DRUG: LIPO-102|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Left Bundle Branch Pacing Versus Right Ventricular Pacing in Patients With Atrioventricular Block
Status: RECRUITING
Conditions: AVB - Atrioventricular Block
Interventions: PROCEDURE: left bundle branch pacing (LBBP)|PROCEDURE: Right ventricular pacing (RVP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2 Study With Panzem in Patients With Relapsed or Plateau Phase Multiple Myeloma
Status: COMPLETED
Conditions: Relapsed Multiple Myeloma|Plateau Phase Multiple Myeloma
Interventions: DRUG: 2-methoxyestradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MK0431 in Patients With Type 2 Diabetes (0431-010)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type II
Interventions: DRUG: MK0431, sitagliptin phosphate / Duration of Treatment: 21 Weeks|DRUG: Comparator: placebo (unspecified) / Duration of Treatment: 21 Weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Rituximab in Treating Patients With Relapsed Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: CHOP regimen|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: prednisone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate Safety And Tolerability Of GSK256066 In Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK256066|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesic Efficacy of Tetracaine Hydrochloride Gel
Status: COMPLETED
Conditions: Hysteroscopy
Interventions: DRUG: Tetracaine hydrochloride gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TAP Blocks vs. IV Lidocaine for Kidney Transplants
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: PROCEDURE: Transversus Abdominis Plane Block|DRUG: Intravenous Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Sleeve Gastrectomy Surgery and External Oblique Intercostal Block
Status: COMPLETED
Conditions: Anesthesia|Regional Anesthesia|Morbid Obesity|Postoperative Pain
Interventions: PROCEDURE: Bilateral ultrasound guided external oblique intercostal block (EOIB)|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Outcomes of FoundationOne Directed Therapy in Cancer of Unknown Primary
Status: COMPLETED
Conditions: Neoplasms, Unknown Primary|CUP|Metastatic Disease|Poorly Differentiated Adenocarcinoma|Poorly Differentiated Carcinoma|Squamous Carcinoma Poorly Differentiated
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial to Evaluate Safety and Immunogenicity of GSK Biologicals' Influenza Vaccine GSK2584786A in Healthy Children
Status: TERMINATED
Conditions: Influenza|Influenza Vaccines
Interventions: BIOLOGICAL: GSK Bio's influenza vaccine GSK2584786A, different formulations|BIOLOGICAL: GSK Bio's influenza vaccine GSK2321138A|BIOLOGICAL: Fluarix™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of Ferric Carboxymaltose to Treat Iron Deficiency in Asians With Heart Failure
Status: COMPLETED
Conditions: Heart Failure|Anemia|Iron Deficiency
Interventions: DRUG: Ferric Carboxymaltose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fractional Laser as Treatment Option for Various Pigment Disorders (Fractional-3)
Status: COMPLETED
Conditions: Pigmentation Disorder
Interventions: DEVICE: Fraxel Restore, Solta Medical Inc. (Non-ablative fractional laser)|DRUG: Modified Kligman's formula (Triple topical therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Abdominal Massage on Palliative Care Patients
Status: COMPLETED
Conditions: Constipation|Abdominal Pain|Palliative Care
Interventions: OTHER: Abdominal massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acute Exposure of Simulated Hypoxia on Heart Rate and Ventilation During Exercise
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DEVICE: Simulated Altitude: (FiO2: 15.1)|DEVICE: Shamed Hypoxia (FiO2: 20.9)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prolonged Exposure for Post Traumatic Stress Disorder (PTSD) With/Without Yohimbine
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: DRUG: Yohimbine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Freeze All on Oocyte Maturatin by Gonadotropin Agonist Versus Human Chorionic Gonadotroipin
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: Agonist (decapeptyl )|DRUG: HCG ( eg. Choriomon )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Yield of Transbronchial Cryobiopsy in Diagnosis of Interstitial Lung Diseases
Status: UNKNOWN
Conditions: Interstitial Lung Disease
Interventions: OTHER: Transbronchial lung cryobiopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Determining the Effects of Risperdal Consta in Patients With Psychotic Disorders and Incomplete Adherence
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Depot Risperidone Microsphere (Consta)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Rural OPTIFAST Intervention for Partial Remission of Type 2 Diabetes in Adults With Obesity
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Obesity
Interventions: DIETARY_SUPPLEMENT: OPTIFAST dietary supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 1% vs. 2 % Lignocaine for Flexible Bronchoscopy
Status: COMPLETED
Conditions: Bronchopulmonary Diseases
Interventions: DRUG: Lignocaine 1% concentration solution|DRUG: Lignocaine 2% concentration solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Implant System for Fixation of Cranial Bone Flaps After Craniotomy for Brain Surgery
Status: COMPLETED
Conditions: Skull Fixation After Craniotomy for Neurosurgical Procedures
Interventions: DEVICE: Skull Grip bone fixation|DEVICE: sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Silicone Hydrogel Contact Lens Wearers to Hydrogel Contact Lens Wearers and Non-lens Wearers
Status: COMPLETED
Conditions: Myopia
Interventions: OTHER: Control|DEVICE: Test Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Tocilizumab Drug Levels to Optimize Treatment in RA
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tocilizumab|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pexelizumab in Patients Undergoing Coronary Artery Bypass Grafting With Cardiopulmonary Bypass (PRIMO-CABG II)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: pexelizumab in conjunction with CABG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intravenous Lidocaine on Pain After Tonsillectomy
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: Intravenous lidocaine injection|DRUG: Intravenous normal saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Prostate Cancer Recurrence With PSMA PET Positive Unilateral Pelvic Lesion(s)
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: PROCEDURE: Salvage Lymphnode dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TWICE-IRI: Optimization of Second-line Therapy With Aflibercept, Irinotecan (Day 1 or Day 1,3), 5-Fluorouracile and Folinic Acid in Patients With Metastatic Colorectal Cancer. A Randomized Phase III Study.
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer Colorectal|Metastasis
Interventions: DRUG: Aflibercept-FOLFIRI|DRUG: Aflibercept-mFOLFIRI3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Of High-Intensity Focused Ultrasound On Abdominal Skin Laxity Post Sleeve Gastrectomy
Status: COMPLETED
Conditions: Skin Laxity|Gastrostomy
Interventions: DEVICE: High intensity focused ultrasound|OTHER: topical firming creams
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Reduction in Sebum (Skin Oil) Induced by Clascoterone Cream 1% in Acne Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Acne Vulgaris
Interventions: DRUG: Winlevi (clascoterone) 1% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Life of Very Preterm Children With Dysexecutive Disorders at Elementary School Age During the Confinement-deconfinement Period of Covid-19 Pandemic
Status: COMPLETED
Conditions: Very Preterm Children With Dysexecutive Disorders
Interventions: OTHER: Patient Quality of life assessment|OTHER: Control group Quality of life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Interactive Voice Response for COVID-19 Vaccination Training in the Democratic Republic of the Congo
Status: COMPLETED
Conditions: COVID-19 Vaccine Knowledge|COVID-19 Vaccine Beliefs
Interventions: BEHAVIORAL: COVID-19 Vaccine IVR Training|BEHAVIORAL: Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S0117 Gemtuzumab Ozogamicin Plus Cytarabine in Treating Patients With Relapsed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: cytarabine|DRUG: gemtuzumab ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rezafungin for Treatment of Pneumocystis Pneumonia in HIV Adults
Status: RECRUITING
Conditions: Pneumocystis Pneumonia
Interventions: DRUG: Co-Trimoxazole|DRUG: Rezafungin Acetate / Co Trimoxazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Normal Values in Ano-rectal 3D High Resolution Manometry
Status: COMPLETED
Conditions: Anorectal Disorder|Fecal Incontinence|Constipation
Interventions: PROCEDURE: Anorectal 3D-high resolution manometry|PROCEDURE: Anorectal radial endosonography (rotative 360° probe)|PROCEDURE: Dynamic anorectal endosonography (sagittal and radial)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bioequivalence Study of Two Formulations of Etoricoxib Tablets 120 mg in Healthy Volunteers Under Fasting Conditions
Status: UNKNOWN
Conditions: Bioequivalence
Interventions: DRUG: Etoricoxib film-coated tablet 120 mg|DRUG: Arcoxia® film-coated tablet 120 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase 1 SAD and MAD Study of the Safety, Tolerability and PK of 7HP349 in Normal Healthy Male Subjects
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: 7HP349 Single Ascending Dose|DRUG: 7HP349 Multiple Ascending Dose|DRUG: Placebo Single Ascending Dose|DRUG: Placebo Multiple Ascending Dose|DRUG: 7HP349 Food Effect
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Novel Treatment Combinations in Participants With Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Neoplasms
Interventions: DRUG: Niraparib|BIOLOGICAL: TSR-042|BIOLOGICAL: Bevacizumab|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Trial to Assess the Safety and Tolerability of Influenza Virus Vaccine, CAIV-T in Healthy Children and Adolescents Ages 6 to Less Than 18 Years.
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Cold-adapted influenza vaccine trivalent (CAIV-T)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Capecitabine in Treating Patients With Advanced or Recurrent Squamous Cell Carcinoma of the Skin
Status: TERMINATED
Conditions: Squamous Cell Carcinoma of the Skin|Recurrent Skin Cancer
Interventions: DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interferon-α Prevents Leukemia Relapse of AML Patients After Transplantation
Status: WITHDRAWN
Conditions: Interferon-A-2B|Relapse|Prevention|Hematopietic Stem Cell Transplantation
Interventions: DRUG: Interferon-alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Efficacy and Safety of Faster Insulin Aspart (Fiasp®) Compared to Conventional Insulin Aspart (NovoLog®) as Correction Bolus
Status: UNKNOWN
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Faster Insulin Aspart (Fiasp®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SMILDA - Symbicort®Turbuhaler® Allergan Challenge Study in Allergic Patients With Mild Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: formoterol|DRUG: budesonide/formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of CAbozantinib in Combination With AtezolizumaB for Muscle-Invasive BladdEr Cancer
Status: RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: Cabozantinib|DRUG: Atezolizumab|PROCEDURE: Cystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dolastatin 10 in Treating Patients With Indolent Lymphoma, Waldenstrom's Macroglobulinemia, or Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: DRUG: dolastatin 10
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise to Improve Balance in Older Adults With Hearing Impairment - a Proof-of-concept Study
Status: UNKNOWN
Conditions: Hearing Loss|Gait, Unsteady|Balance; Distorted|Old Age; Debility
Interventions: OTHER: Virtual reality exercise|OTHER: Vestibular rehabilitation exercise|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sym004 in Subjects With Stage IV Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Part 1: Sym004 6 mg/kg + Cisplatin/Gemcitabine|DRUG: Part 1: Sym004 6 mg/kg + Cisplatin/Pemetrexed|DRUG: Part 1: Sym004 6 mg/kg + Carboplatin/Paclitaxel|DRUG: Part 1: Sym004 6/12 mg/kg + Carboplatin/Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pemetrexed Versus Gefitinib in Patients With Locally Advanced or Metastatic Non Small Cell Lung Cancer Who Have Previously Received Platinum-Based Chemotherapy Without Epidermal Growth Factor Receptor (EGFR) Mutations
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Pemetrexed (Alimta)|DRUG: Gefitinib (IRESSA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DCE-MRI and DWI for Detection and Diagnosis of Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|BIRADS 3|BIRADS 4|BIRADS 5
Interventions: PROCEDURE: DCE-MRI and DWI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Removing Barriers: Community Partnering for Innovative Solutions to the Opioid Crisis
Status: RECRUITING
Conditions: Opioid Use Disorder|Alcohol Use Disorder|Health Risk Behaviors|Criminal Behavior|Housing Problems|Overdose of Opiate
Interventions: BEHAVIORAL: Removing Barriers to Recovery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SERENDEM : MD1003 in Patients Suffering From Demyelinating Neuropathies, an Open Label Pilot Study
Status: COMPLETED
Conditions: Chronic Inflammatory Demyelinating Polyneuropathy|Peripheral Neuropathy|Charcot-Marie-Tooth Disease|Charcot-Marie-Tooth Disease Type 1A|Charcot-Marie-Tooth Disease, Type 1B|Anti-MAG Neuropathy
Interventions: DRUG: MD1003
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Omega 3 on Periodontitis in Postmenopausal Women
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DIETARY_SUPPLEMENT: Omega 3 fatty acids|PROCEDURE: scaling and root planing|OTHER: placebo soft gelatin capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Pharmacokinetic and Mass Balance of Single Dose [14C] AZD9291 in Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AZD9291
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: PARTNER: Panitumumab Added to Regimen for Treatment of Head aNd Neck Cancer Evaluation of Response
Status: COMPLETED
Conditions: Metastatic or Recurrent Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: Cisplatin|DRUG: Panitumumab|DRUG: Docetaxel|DRUG: Cisplatin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Indocyanine Green Tracer Using in Laparoscopic Gastrectomy With Lymph Node Dissection
Status: COMPLETED
Conditions: Stomach Neoplasms|Indocyanine Green
Interventions: DRUG: Indocyanine Green Tracer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Partial Brain RT, Temozolomide, Chloroquine, and TTF Therapy for the Treatment of Newly Diagnosed Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma|Gliosarcoma
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|RADIATION: Intensity-Modulated Radiation Therapy (IMRT)|DRUG: Temozolomide|DRUG: Chloroquine|PROCEDURE: Tumor Treating Fields Therapy (TTF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Amigo Robotic System for Ablation of the Cavo-Tricuspid Isthmus
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DEVICE: Amigo™ Robotic Catheter Manipulation|DEVICE: Manual Catheter Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Iontophoretic Application of Terbinafine Gel in Subjects With Onychomycosis
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DRUG: Terbinafine Hydrochloride|OTHER: Purified Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immune System Stimulation by Probiotic Food Supplementation
Status: COMPLETED
Conditions: Flu Symptom
Interventions: DIETARY_SUPPLEMENT: Weiquan Yogurt with probiotics|DIETARY_SUPPLEMENT: Weiquan Yogurt without probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oral Branched-chain Amino Acid Supplementation for Decompensated Cirrhotic Patients
Status: RECRUITING
Conditions: Decompensated Cirrhosis and Ascites
Interventions: DRUG: Branched-chain amino acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance Output With Haptics - Evaluating Athlete Response and Unrealized Potential
Status: NOT_YET_RECRUITING
Conditions: Muscle Strength|Muscle Weakness
Interventions: DEVICE: VICTORY PATCH|DEVICE: Sham Patch without VTT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Confirmatory Study of OPC-12759 Ophthalmic Suspension
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: OPC-12759 Ophthalmic suspension|DRUG: Hyalein Mini Ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Efficacy and Safety of JETi® in Arterial Occlusions in FEM-POP and Prox BTK-Lesions (JETART)
Status: NOT_YET_RECRUITING
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: JETi 6F and 8F Thrombectomy system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular and Cognitive Fatigue During a 24 Hour Treadmill Running Exercise
Status: COMPLETED
Conditions: Healthy
Interventions: PROCEDURE: running during 24 hours without sleep|OTHER: no sleeping
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: IPACK Study in Total Knee Arthroplasty Patients
Status: COMPLETED
Conditions: Knee Replacement Arthroplasty
Interventions: DRUG: Standard of Care (ACB, SA, peri-op pain management)|DRUG: IPACK and multi-modal analgesic regimen|PROCEDURE: Periarticular Local Anesthetic Infiltration|DRUG: IV Dexamethasone 8mg at the end of surgery as standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of a New Supplement for Hair and Nails - in Vitro, Clinical, Subjective and Instrumental Study
Status: COMPLETED
Conditions: Hair Loss|Nails, Ingrown
Interventions: DIETARY_SUPPLEMENT: A power supplement with biotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT