pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Neuropsycatric Disorders Among Children With Systemic Lupus Erythematosus in Sohag University Hospital
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DIAGNOSTIC_TEST: Anti Phospholipid antibodies|RADIATION: EEG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Augmented Effects of Virtual-reality Cycling Training on Upper Limb Motor Functions by NIBS in Patients With CP
Status: UNKNOWN
Conditions: Cerebral Palsy
Interventions: DEVICE: Virtual cycling training|DEVICE: Repetitive transcranial magnetic stimulation|DEVICE: Transcranial electric stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Education in Preventing Nausea and Vomiting in Cancer Patients Receiving Chemotherapy
Status: COMPLETED
Conditions: Nausea and Vomiting|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose:
Clinical trial: The Effect of Chlorhexidine on the Oral Microbiome and Saliva in Dental Erosion
Status: NOT_YET_RECRUITING
Conditions: Dental Erosion
Interventions: COMBINATION_PRODUCT: Chlorhexidine mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetics and Safety of Single-Dose Telbivudine in Children and Adolescents With Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: LDT600 (Telbivudine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Identification of Biomarkers for Early Detection of Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: GENETIC: protein expression analysis|OTHER: laboratory biomarker analysis|OTHER: mass spectrometry|OTHER: surface-enhanced laser desorption/ionization-time of flight mass spectrometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Healthy Relationships Program for 2SLGBTQIA+ Youth
Status: COMPLETED
Conditions: Adolescent Development
Interventions: BEHAVIORAL: Healthy Relationships Program (HRP) for 2SLGBTQIA+ Youth|BEHAVIORAL: Standard GSA Programming
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Influence of Probiotics on Body Weight and Composition
Status: WITHDRAWN
Conditions: Healthy|Overweight
Interventions: DIETARY_SUPPLEMENT: Probiotic|BEHAVIORAL: Behavioral lifestyle intervention|OTHER: Placebo|OTHER: Blood Test|DIETARY_SUPPLEMENT: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pembrolizumab in Treating Patients With EGFR Mutant, Tyrosine Kinase Inhibitor Naive Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Stage IIIA Non-Small Cell Lung Cancer|Stage IIIB Non-Small Cell Lung Cancer|Stage IV Non-Small Cell Lung Cancer
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Sildenafil Treatment in Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Posterior Retroperitoneoscopic Adrenalectomy: A Comparative Study
Status: COMPLETED
Conditions: Adrenal Mass|Adrenal Disease|Pheochromocytoma|Cushing Syndrome
Interventions: PROCEDURE: Posterior retroperitoneoscopic adrenalectomy|PROCEDURE: Transperitoneal laparoscopic adrenalectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Chronocort Versus Standard Hydrocortisone Replacement Therapy in Participants Aged 16 Years and Over With Congenital Adrenal Hyperplasia
Status: COMPLETED
Conditions: Congenital Adrenal Hyperplasia
Interventions: DRUG: Chronocort|DRUG: Cortef
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROphylaxis in NOn Major Orthopaedic Surgery
Status: TERMINATED
Conditions: Non-major Orthopaedic Surgery
Interventions: DRUG: Rivaroxaban|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Masseter Muscle Thickness in Gasser Ganglion Radiofrequency Treatment
Status: NOT_YET_RECRUITING
Conditions: Trigeminal Neuralgia|Gasserian Ganglion; Lesion
Interventions: PROCEDURE: Gasserian Ganglion Radiofrequency Thermocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Assessment of Synaptic Density in Progressive MS
Status: UNKNOWN
Conditions: Primary Progressive Multiple Sclerosis|Secondary Progressive Multiple Sclerosis|Relapsing Multiple Sclerosis|Multiple Sclerosis
Interventions: DRUG: [F-18]SDM-8
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Left Atrial Function Analysis for Patients With Persistent Atrial Fibrillation Undergoing Pulmonary Vein Isolation
Status: UNKNOWN
Conditions: Persistent Atrial Fibrillation|Catheter Ablation
Interventions: DIAGNOSTIC_TEST: LA pressure, voltage map, strain, scar-map, blood sampling|PROCEDURE: pulmonary vein isolation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: REMINISCENCES and EMOTIONS : Reminiscence Triggered by Virtual Reality for Older Adults With Mood Disorders
Status: COMPLETED
Conditions: Alzheimer Disease|Mood Disorders|Virtual Reality
Interventions: PROCEDURE: virtual reality session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vitamin E, Selenium, and Soy Protein in Preventing Cancer in Patients With High-Grade Prostate Neoplasia
Status: COMPLETED
Conditions: Precancerous/Nonmalignant Condition|Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: selenium|DIETARY_SUPPLEMENT: soy protein isolate|DIETARY_SUPPLEMENT: vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Remifentanil on ED95 of Remimazolam for Loss of Consciousness in Adult Patients
Status: UNKNOWN
Conditions: Remimazolam
Interventions: DRUG: Remimazolam|DRUG: remifantanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Comparison of Two Injection Locations in Obese Patients Having Lower Leg/Foot Surgery
Status: COMPLETED
Conditions: Strain of Muscle and/or Tendon of Lower Leg|Fracture of Lower Leg|Crushing Injury of Lower Leg|Fracture Malunion - Ankle and/ or Foot|Complete Tear, Ankle and/or Foot Ligament|Pathological Fracture - Ankle and/or Foot|Loose Body in Joint of Ankle and/or Foot
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Multiple BI 1356 Doses of on the Multiple-dose Pharmacokinetics of a Combination of Ethinylestradiol and Levonorgestrel in Healthy Female Premenopausal Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Microgynon®|DRUG: BI 1356
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Tosylate With or Without Recombinant Interferon Alfa-2b in Treating Patients With Metastatic Kidney Cancer
Status: COMPLETED
Conditions: Clear Cell Renal Cell Carcinoma|Recurrent Renal Cell Carcinoma|Stage IV Renal Cell Cancer
Interventions: DRUG: Sorafenib Tosylate|BIOLOGICAL: Recombinant Interferon Alfa-2b|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lung Ultrasound Score and Inferior Vena Cava Diameter Compared to Pulse Pressure Variation
Status: RECRUITING
Conditions: Sepsis|Critical Illness
Interventions: DRUG: normal Saline|DEVICE: lung ultrasound|DEVICE: inferior vena cava measurements|DIAGNOSTIC_TEST: passive leg raising test (PLRT)|DEVICE: pulse pressure variation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Sucrose to Relieve Pain During Eye Exams in Infants
Status: TERMINATED
Conditions: Apnea of Prematurity|Retinopathy of Prematurity|Pain
Interventions: DIETARY_SUPPLEMENT: sucrose solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Cytoreduction and Intraperitoneal Chemotherapy Versus Systemic Chemotherapy in Colorectal Peritoneal Carcinomatosis
Status: COMPLETED
Conditions: Colorectal Peritoneal Carcinomatosis
Interventions: DRUG: Systemic chemotherapy alone (oxaliplatin, 5-fluorouracil, isovorin)|PROCEDURE: Cytoreductive surgery (CRS) plus postoperative intraperitoneal chemotherapy (5-fluorouracil, isovorin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga-DOTA-MGS5 PET/CT in Patients With Advanced Neuroendocrine Tumours
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: 68Ga-DOTA-MGS5
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the ZyMōt Sperm Selection Method and Its Effect on Embryo Ploidy.
Status: RECRUITING
Conditions: Infertility, Male|Sperm Count, Low
Interventions: DEVICE: Sperm capacitation through the ZyMōt®Sperm Separation Device®|PROCEDURE: Swim-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Combining mFOLFOX6 With Tivozanib or Bevacizumab in Patients With Metastatic Colorectal Cancer as First Line Therapy
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Tivozanib|DRUG: Bevacizumab|DRUG: mFOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sitagliptin vs. Pioglitazone as add-on Treatments in Patients With Type 2 Diabetes Uncontrolled on the Full-dose Metformin Plus Sulfonylurea
Status: COMPLETED
Conditions: Uncontrolled Type 2 Diabetes Mellitus
Interventions: DRUG: Sitagliptin 100mg|DRUG: Pioglitazone 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resistance Training in Elderly
Status: COMPLETED
Conditions: Sarcopenia|Atrophy|Aging
Interventions: DIETARY_SUPPLEMENT: protein drink|BEHAVIORAL: Resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: In-Vivo Assessment of Silver Biomaterial Nano-Toxicity 32 Ppm
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 32ppm Silver Particle|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Safety and Efficacy of Strategy to Prevent Drug-Induced Nephrotoxicity in High-Risk Patients
Status: TERMINATED
Conditions: Health Care Associated Pneumonia|Osteomyelitis/Septic Arthritis|Endocarditis|Bacteremia|Acute Bacterial Skin and Skin Structure Infections
Interventions: DRUG: Vancomycin|DRUG: Ceftaroline|DRUG: Daptomycin|DRUG: Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Toripalimab Plus Lenvatinib and Gemcitabine-based Chemotherapy in 1L Treatment of Advanced ICC: a Phase III Study
Status: NOT_YET_RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Toripalimab|DRUG: Lenvatinib mesylate capsules|DRUG: Placebo IV|DRUG: Oral placebo|DRUG: Oxaliplatin for injection|DRUG: Gemcitabine hydrochloride|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Single and Multiple Doses of SoftOx Biofilm Eradicator (SBE) in Chronic Leg Wounds
Status: COMPLETED
Conditions: Chronic Leg Ulcer|Venous Leg Ulcer
Interventions: DRUG: SoftOx Biofilm Eradicator (Groups 1 to 7)|DEVICE: Sterile isotonic saline (Groups 1 to 4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Erector Spinal Block Improve Quality of Recovery After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Postoperative Recovery
Interventions: OTHER: local anesthetic injection|OTHER: Standard perioperative and postoperative analgesia protocol.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Study With GFT505 (80mg) Versus Placebo in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type II Diabetes Mellitus
Interventions: DRUG: GFT505 80mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Kinesio Taping® in Paretic Tibialis Anterior Muscle During Patient Gait and Balance After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Kinesio Taping|DEVICE: Kinesio Taping Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lactoferrin Effect on Kidney and Heart of Rhabdomyolysis Rats
Status: NOT_YET_RECRUITING
Conditions: Rhabdomyolysis
Interventions: DRUG: Lactoferrin|DIAGNOSTIC_TEST: iron|DIAGNOSTIC_TEST: MDA, TAC, and GSH|DIAGNOSTIC_TEST: Nrf2|DIAGNOSTIC_TEST: AMPK|DIAGNOSTIC_TEST: HO-1|DRUG: glycerin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mycophenolate Mofetil for Reducing Cardiovascular Risk in Renal Transplant Recipients
Status: TERMINATED
Conditions: Kidney Transplantation|Cardiovascular Diseases
Interventions: DRUG: mycophenolate mofetil|OTHER: standard immunosuppression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Nafamostat Mesilate in Prolonging Filter Patency With Patients on Continuous Renal Replacement Therapy
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: Anticoagulation with nafamostat mesilate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: autologous dendritic cell-adenovirus CCL21 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suvorexant and Sleep/Delirium in ICU Patients
Status: RECRUITING
Conditions: Insomnia|Sleep Fragmentation|Sleep Initiation and Maintenance Disorders|Postoperative Delirium
Interventions: DRUG: Suvorexant 20 mg|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microperimetry and Optical Coherence Tomography (OCT) With Lucentis for Diabetic Macular Edema (DME)
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Economic Outcomes in Laparoscopic Sleeve Gastrectomy Versus Roux-en-Y Gastric Bypass Surgery
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: PROCEDURE: Gastric Sleeve Resection|PROCEDURE: Roux-en-Y Gastric Bypass
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase IIa Study of ALLN-346 (Engineered Urate Oxidase) in Subjects With Hyperuricemia, Gout and Chronic Kidney Disease
Status: TERMINATED
Conditions: Hyperuricemia|Gout|Chronic Kidney Diseases
Interventions: DRUG: ALLN-346|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dentine Tubule Occlusion Assessment in a Modified in Situ Model
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: DEVICE: Stannous fluoride|OTHER: Sodium monofluorophosphate|OTHER: Mineral water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Gum Chewing or Walking on Bowel Prep Quality and Patient Satisfaction Before Colonoscopy
Status: NOT_YET_RECRUITING
Conditions: Colonoscopy|Bowel Preparation
Interventions: OTHER: Chewing Gum|OTHER: Walking Exercise|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Alogliptin Combined With Pioglitazone in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Alogliptin and pioglitazone|DRUG: Alogliptin and pioglitazone|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Safety of GSI 136 in Young and Elderly Japanese Males
Status: COMPLETED
Conditions: Alzheimer Disease|Healthy
Interventions: DRUG: GSI 136|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Alisporivir Triple Therapy in Chronic Hepatitis C Genotype 1 Treatment-naïve Participants
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Alisporivir|DRUG: Peginterferon alfa-2a|DRUG: Ribavirin|DRUG: ALV Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fibrosis in Renal Allografts
Status: UNKNOWN
Conditions: Kidney Failure, Chronic|Transplantation|Immunosuppression|Interstitial Fibrosis
Interventions: DRUG: sirolimus|DRUG: cyclosporine|DRUG: daclizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Effectiveness and Safety of Sublingual Immunotherapy in Children With Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: BIOLOGICAL: sublingual allergen extract|BIOLOGICAL: sublingual allergen extract|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunomodulation Therapy for Urinary Tract Infections
Status: COMPLETED
Conditions: Spinal Cord Injuries|Urinary Tract Infections
Interventions: DRUG: Uro-Vaxom|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Evaluation of Safety and Efficacy of Anecortave Acetate Versus Placebo in Patients With Subfoveal CNV Due to Exudative AMD
Status: COMPLETED
Conditions: Macular Degeneration|Maculopathy, Age-Related
Interventions: DRUG: anecortave acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Intervention to Motivate Standing &Walking in Gastrointestinal Cancer Surgical Patients
Status: COMPLETED
Conditions: Gastrointestinal Neoplasms
Interventions: BEHAVIORAL: Education/Daily Planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does a Novel Needle Over Catheter Device Improve First Pass Success and Decrease Complications
Status: NOT_YET_RECRUITING
Conditions: Vascular Access Device Complications|Catheterization, Peripheral
Interventions: DEVICE: Osprey IV|OTHER: Historical Controls
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measuring Cowpea Consumption in Young Children and Pregnant Women in Ghana
Status: COMPLETED
Conditions: Dietary Exposure
Interventions: DIETARY_SUPPLEMENT: cowpea variety #1|DIETARY_SUPPLEMENT: cowpea variety #2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Systemic Ketamine for the Improvement of Post-Operative Analgesia at the Alcohol-Dependent Patient
Status: SUSPENDED
Conditions: Alcoholic Patient|Carcinological Surgery ORL
Interventions: DRUG: ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hypoalgesic Effect of Neural Mobilization
Status: COMPLETED
Conditions: Cervicobrachial Neuralgia
Interventions: PROCEDURE: Cervical Lateral Glide neural mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Polyphenol-rich Cocoa Extract on Peripheral Blood Mononuclear Cells Gene Expression
Status: COMPLETED
Conditions: Cardiovascular Function|Gene Expression
Interventions: DIETARY_SUPPLEMENT: Polyphenol-rich cocoa extract|DIETARY_SUPPLEMENT: Chocolate cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Squire's Quest! II: Implementation Intentions and Children's Fruit, Juice, and Vegetable (FJV) Consumption
Status: COMPLETED
Conditions: Obesity|Cancer
Interventions: BEHAVIORAL: simple goal setting|BEHAVIORAL: goal setting plus action intentions|BEHAVIORAL: goal setting plus coping intentions|BEHAVIORAL: goal setting plus action intentions plus coping intentions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Efficacy of Lithium Carbonate in Spinal Cord Injury Patients With Neuropathic Pain
Status: COMPLETED
Conditions: Neuropathic Pain|Neuralgia|Spinal Cord Injuries
Interventions: DRUG: Lithium Carbonate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sonography in an Unselected Population of Acute Admitted Patients With Respiratory Symptoms
Status: COMPLETED
Conditions: Dyspnoea|Chest Pain|Cough
Interventions: OTHER: Focused Sonography of the heart, lungs and deep veins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Operative Versus Non-Operative Treatment for Atraumatic Rotator Cuff Tears
Status: ACTIVE_NOT_RECRUITING
Conditions: Rotator Cuff Tear
Interventions: PROCEDURE: Operative|PROCEDURE: Non-Operative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid 10-Minute Liver MRI Protocol in Patients With Suspected Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Underlying Liver Disease|Hepatitis|Fibrosis of Liver|Cirrhosis With Suspicion of Liver Cancer|Lesion on a Prior Ultrasound, CT or Outside MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fetal Middle Cerebral Artery Doppler in Preterm Births Receiving Magnesium Sulfate for Neuroprotection
Status: COMPLETED
Conditions: Preterm Birth
Interventions: DRUG: Magnesium Sulfate|OTHER: 0.9% sodium chloride solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: AC-1204 26-Week Long Term Efficacy Response Trial With Optional Open-label Ext
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: AC-1204|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Perioperative TEAS on Postoperative Pain and Agitation in Pediatric Adenoidectomy and Tonsillectomy
Status: UNKNOWN
Conditions: the Effect of TEAS on the Children' Pain and Agitation
Interventions: OTHER: transcutaneous electrical acupoint stimulation(TEAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prospective, Multicenter, Multidisciplinary, Controlled Clinical Investigation Evaluating the Safety and Efficacy of PerClot® Polysaccharide Hemostatic System
Status: COMPLETED
Conditions: Blood Loss, Surgical
Interventions: DEVICE: PerClot Polysaccharide Hemostatic System|DEVICE: Arista AH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cycloserine in the Treatment of Sleep Apnea
Status: TERMINATED
Conditions: Sleep Apnea Syndromes
Interventions: DRUG: Cycloserine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Epoetin Beta (NeoRecormon) in Participants With Solid Tumors or Hematologic Malignancies
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Epoetin beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Training Program for Parents of Babies in Their First Year of Life to Achieve Motor Milestones
Status: COMPLETED
Conditions: Term|Healthy|Motor Delay|Development, Infant
Interventions: OTHER: Training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Perioperative Glucocorticoid Replacement on Prognosis of Surgical Patients With Sellar Lesions
Status: UNKNOWN
Conditions: Pituitary Neoplasms|Craniopharyngiomas
Interventions: DRUG: Hydrocortisone|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab, Cisplatin, Radiation Therapy, and Fluorouracil in Treating Patients With Stage IIB, Stage III, Stage IVA, or Stage IVB Nasopharyngeal Cancer
Status: COMPLETED
Conditions: Stage II Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7|Stage III Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7|Stage III Nasopharyngeal Undifferentiated Carcinoma AJCC v7|Stage IV Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7|Stage IV Nasopharyngeal Undifferentiated Carcinoma AJCC v7
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|BIOLOGICAL: Bevacizumab|DRUG: Cisplatin|DRUG: Fluorouracil|RADIATION: Intensity-Modulated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double-blind, Placebo, Controlled Cross Over Design Topical Morphine for Analgesia in Pediatric Procedures
Status: WITHDRAWN
Conditions: Pain
Interventions: DRUG: Topic Morphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Ramelteon in Elderly Subjects With Chronic Insomnia.
Status: COMPLETED
Conditions: Chronic Insomnia
Interventions: DRUG: Ramelteon and Placebo (9 possible combinations total)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate EuHZV in Healthy Adults Aged 50 to 69 Years
Status: RECRUITING
Conditions: Varicella Zoster Virus Infection|Herpes Zoster
Interventions: BIOLOGICAL: EuHZV|BIOLOGICAL: Shingrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Fasting Study of Chlorpheniramine Polistirex and Hydrocodone Polistirex Capsules and Tussionex® Pennkinetic® Extended Release Oral Suspension
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Chlorpheniramine polistirex equivalent to 8 mg of chlorpheniramine maleate and hydrocodone polistirex equivalent to 10 mg of hydrocodone bitartrate capsule|DRUG: 5 mL chlorpheniramine (8 mg/5 mL)/hydrocodone (10 mg/5 mL) extended release oral suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Lemborexant Treatment of Insomnia Linked to Epilepsy
Status: RECRUITING
Conditions: Epilepsy|Sleep
Interventions: DRUG: Lemborexant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Comparison of Immediate and Controlled Release Formulations of Ecopipam
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ecopipam immediate release form|DRUG: 90 mg controlled release form|DRUG: 180 mg controlled release form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Visilizumab in Subjects With Intravenous Steroid-Refractory Ulcerative Colitis
Status: WITHDRAWN
Conditions: Intravenous Steroid-Refractory Ulcerative Colitis
Interventions: DRUG: Visilizumab (HuM291; Nuvion®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: COVID-OUT: Early Outpatient Treatment for SARS-CoV-2 Infection (COVID-19)
Status: COMPLETED
Conditions: Covid19|SARS-CoV Infection
Interventions: DRUG: Metformin|DRUG: Placebo|DRUG: Fluvoxamine|DRUG: Ivermectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lotto to Link Study: A Prospective, Interventional, Randomized Study of Conditional Incentives
Status: COMPLETED
Conditions: Incentives|HIV Infections|ART
Interventions: OTHER: Conditional lottery incentive|OTHER: Optimized ART linkage package
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Metformin Treatment in Adolescent Patients With PCOS: A Long-term, Winning Metabolic Choice.
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Community Level Interventions for Pre-eclampsia
Status: COMPLETED
Conditions: Pre-eclampsia|Hypertension, Pregnancy Induced
Interventions: BEHAVIORAL: Community Engagement|DEVICE: PIERS on the Move mHealth decision aid|DRUG: Magnesium Sulfate|DRUG: Methyldopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: AVIATION Study: A Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy Study of TERN-201 in Patients With Non-Cirrhotic Non-Alcoholic Steatohepatitis
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: TERN-201|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Japan Early Diabetes Intervention Study
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: BEHAVIORAL: Standard lifestyle guidance|DRUG: Lifestyle guidance and monotherapy with acarbose|DRUG: Lifestyle guidance and monotherapy with metformin|DRUG: Lifestyle guidance and monotherapy with gliclazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Specific Cervicograph for Women Attempting at Vaginal Delivery After Cesarean Section
Status: COMPLETED
Conditions: Attempted Vaginal Delivery After a Cesarean Section
Interventions: DIAGNOSTIC_TEST: specific cervicograph
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Neoadjuvant of Axitinib Plus PD-1 to Improve Disease Free Survival of Patients With Renal Cell Carcinoma
Status: RECRUITING
Conditions: Renal Cell Carcinoma|Neoadjuvant
Interventions: DRUG: Axitinib plus Toripalimab|PROCEDURE: nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brief Cognitive Behavioral Therapy for Chronic Pain to Improve Functioning Among Veterans
Status: RECRUITING
Conditions: Musculoskeletal Pain|Pain
Interventions: BEHAVIORAL: Brief CBT for Chronic Pain|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Teleoperation Experimental Comparison With Able-bodied Subjects
Status: COMPLETED
Conditions: Amputation; Traumatic, Arm, Upper
Interventions: DEVICE: Semi-autonomous myoelectric control algorithm|DEVICE: Standard-of-care myoelectric control algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Postoperative Pain Control Using ON-Q Painbuster Pump
Status: COMPLETED
Conditions: Post Operative Analgesia
Interventions: DRUG: levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation on Safety, Feasibility and Usability of the ABLE Exoskeleton Device With Spinal Cord Injured Patients in a Hospital Setting
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DEVICE: ABLE Exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhanced Child Friendly Space Interventions for Children
Status: COMPLETED
Conditions: Psychosocial Stressors|Child, Only|Mental Health Wellness 1|Child Development
Interventions: BEHAVIORAL: Child Friendly Space
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparing the Pharmacokinetic and Safety of QL1203 and Vectibix® in Healthy Males.
Status: UNKNOWN
Conditions: Healthy Males
Interventions: DRUG: QL1203|DRUG: Vectibix®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effects of Glucodia™ on Glucose Parameters, Triglycerides and Body Weight
Status: COMPLETED
Conditions: Glucose Parameters|Triglycerides|Body Weight
Interventions: DIETARY_SUPPLEMENT: Glucodia™|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Safety and Efficacy of a Novel Glucagon Formulation in Type 1 Diabetic Patients Following Insulin-induced Hypoglycemia
Status: COMPLETED
Conditions: Hypoglycemia
Interventions: DRUG: Nasal Glucagon 1 mg|DRUG: Nasal Glucagon 2 mg|DRUG: SC Glucagon|DRUG: Nasal Glucagon 3 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Neuropathic Pain Following Spinal Cord Injury - a rTMS Approach
Status: NOT_YET_RECRUITING
Conditions: Neuropathic Pain
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Laparoscopic Splenectomy and Azygoportal Disconnection on the Immune Function for Cirrhosis Patients
Status: RECRUITING
Conditions: Cirrhosis, Liver|Splenectomy; Status
Interventions: PROCEDURE: Laparoscopic splenectomy and azygoportal disconnection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CIVETTA: Correlating Inflammatory Values of FEno, SympToms, SpuTum and Lung Function in Asthma
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma
Interventions: DRUG: Salbutamol|DRUG: Fluticason either Beclometasone or Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cochicine Treatment for Post- Operative Pericardial Effusion
Status: COMPLETED
Conditions: Pericardial Effusion
Interventions: DRUG: Colchicines|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab, Lenalidomide, and Bortezomib in Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Rituximab|DRUG: Bortezomib|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Safety, Tolerability and Pharmacokinetic Study of NCTX in Healthy Volunteers
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: NCTX (PEGylated Liposomal Iodixanol Injection)|DRUG: Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of AROSOD-1 in Adult Participants With Amyotrophic Lateral Sclerosis (ALS)
Status: WITHDRAWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: ARO-SOD1 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Sunitinib Malate in Patients With Newly Diagnosed Prostate Cancer Prior to Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer|Prostatectomy
Interventions: DRUG: Sunitinib Malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cannabidiol (CBD) on the Brain
Status: ACTIVE_NOT_RECRUITING
Conditions: CBD|Fear|Inhibition
Interventions: DRUG: Cannabidiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sirolimus+Abatacept+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to Calcineurin Inhibitors
Status: NOT_YET_RECRUITING
Conditions: Acute Leukemia|Myelodysplastic Syndromes|Severe Aplastic Anemia
Interventions: DRUG: Sirolimus|DRUG: Abatacept|DRUG: MMF|DRUG: ATG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Application of a Simplified Method of Complete Denture Fabrication for Severely Resorbed Mandibular Ridges
Status: UNKNOWN
Conditions: Edentulous Mouth|Edentulous Jaw
Interventions: PROCEDURE: Denture fabrication technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Providing Mental Health Precision Treatment
Status: ENROLLING_BY_INVITATION
Conditions: Depression|Addiction|Anxiety|Sleep Disturbance
Interventions: BEHAVIORAL: Enhanced Feedback + Standard Feedback|DEVICE: Headspace app + Standard Feedback|DEVICE: Headspace app + Enhanced Feedback + Standard Feedback|DEVICE: SilverCloud + Standard Feedback|DEVICE: SilverCloud app +Enhanced Feedback +Standard Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic nHCM
Status: RECRUITING
Conditions: Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy
Interventions: DRUG: Aficamten|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Restoring Metabolic and Reproductive Health With Sleep in PCOS Study, CPAP Trial
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome|Obstructive Sleep Apnea
Interventions: DEVICE: Continuous Positive Airway Pressure Device (CPAP)|OTHER: Delayed Continuous Positive Airway Pressure Device (CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Two Treatments in the Treatment of Acne Vulgaris on the Face
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Adapalene and Benzoyl Peroxide Topical Gel|DRUG: Epiduo Topical Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Modulation of Neuroinflammation in Age-Related Memory Disorders
Status: COMPLETED
Conditions: Memory Loss|Inflammation
Interventions: DIETARY_SUPPLEMENT: 650 mg of Cocoapro flavanols|DIETARY_SUPPLEMENT: 0 mg of Cocoapro flavanols
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I Study of Surface-Controlled Water Soluble Curcumin (THERACURMIN CR-011L)
Status: COMPLETED
Conditions: Advanced Cancers
Interventions: DRUG: Surface-Controlled Water Soluble Curcumin|DRUG: Surface-Controlled Water Soluble Curcumin MTD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Safety and Efficacy of Bimiralisib Gel in Participants Suffering From Actinic Keratosis
Status: RECRUITING
Conditions: Actinic Keratosis
Interventions: DRUG: Bimiralisib|DRUG: Bimiralisib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of CF-DNA in Patients With Gastrointestinal Stromal Tumors (GIST)
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: OTHER: Blood will be withdrawn at baseline and in intervals of 3 months for a total period of 2 years
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bevacizumab Plus Vinorelbine in Treating Patients With Stage IV Breast Cancer
Status: COMPLETED
Conditions: Male Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: vinorelbine tartrate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT