pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effectiveness of a Structured Physical Rehabilitation Program for Chinese Patients With Depressive Disorders
Status: COMPLETED
Conditions: Depressive Disorders
Interventions: OTHER: Exercise Intervention -- Physical Rehabilitation Program|OTHER: Wait List Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of Thoracolumbar Spinal Fusion Graft
Status: ACTIVE_NOT_RECRUITING
Conditions: Lumbar Degenerative Disc Disease
Interventions: PROCEDURE: BMAC & Allograft|PROCEDURE: Iliac Crest Bone Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: GIP Effects at Insulin Induced Hypoglycemia in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: Glucose-dependent Insulinotropic polypeptide|OTHER: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ultrasound-guided Botulinum Toxin Injection on Cricopharyngeal Muscle Dysfunction
Status: NOT_YET_RECRUITING
Conditions: Cricopharyngeal Achalasia
Interventions: DRUG: botulinum toxin type A|PROCEDURE: Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Enbrel (Etanercept) Plus Methotrexate Versus Enbrel Alone in Active Rheumatoid Arthritis Despite Current Methotrexate Therapy
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Methotrexate plus ENBREL or ENBREL alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide Versus Dolutegravir + Emtricitabine/Tenofovir Alafenamide in Human Immunodeficiency Virus (HIV-1) Infected, Antiretroviral Treatment-Naive Adults
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: DTG|DRUG: F/TAF|DRUG: B/F/TAF|DRUG: DTG Placebo|DRUG: F/TAF Placebo|DRUG: B/F/TAF Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on Better Cognitive Functioning Through Braintraining on the Internet
Status: COMPLETED
Conditions: Depression|Late Life Mood Disorder|Impaired Cognition|Alteration in Mood|Alteration in Cognition
Interventions: BEHAVIORAL: Online cognitive training 1|BEHAVIORAL: Online cognitive training 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Reduction Using NEurostimulation Study
Status: RECRUITING
Conditions: End Stage Kidney Disease|Chronic Pain
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Second Comparative Study of Specular Microscopes for Endothelial and Corneal Cell Measurements
Status: COMPLETED
Conditions: Corneal Endothelial Cell Loss
Interventions: DEVICE: Topcon Specular Microscope SP-1P|DEVICE: Konan Specular Microscope CELLCHEK XL
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SUTURE-CLOSURE OMENTOPEXY VERSUS OMENTOPEXY ALONE IN REPAIR OF PERFORATED PEPTIC ULCER
Status: RECRUITING
Conditions: Perforated Peptic Ulcer
Interventions: PROCEDURE: SUTURE-CLOSURE OMENTOPEXY IN REPAIR OF PERFORATED PEPTIC ULCER|PROCEDURE: OMENTOPEXY ALONE IN REPAIR OF PERFORATED PEPTIC ULCER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultraviolet Light Therapy Using Methoxsalen With or Without Bexarotene in Treating Patients With Mycosis Fungoides
Status: TERMINATED
Conditions: Lymphoma
Interventions: DRUG: bexarotene|DRUG: methoxypsoralen|PROCEDURE: UV light therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the ZoMaxx™ Drug-Eluting Stent System in Coronary Arteries
Status: COMPLETED
Conditions: Coronary Disease|Coronary Artery Disease|Coronary Restenosis
Interventions: DEVICE: ZoMaxx™ Drug-Eluting Coronary Stent System|DEVICE: TAXUS™ EXPRESS2™ Paclitaxel Eluting Coronary Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Verapamil vs Steroid to Prevent Keloid Recurrence
Status: TERMINATED
Conditions: Keloid Scars
Interventions: DRUG: Verapamil|DRUG: Kenalog 10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Exercise and Weight Loss on Cardiovascular Health
Status: COMPLETED
Conditions: Cardiovascular Disease|Obesity
Interventions: BEHAVIORAL: Behavioral weight loss intervention|BEHAVIORAL: Diet Plus Moderate Exercise|BEHAVIORAL: Diet Plus High Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Coronary Atherosclerosis T1-Weighted Characterization (CATCH)
Status: RECRUITING
Conditions: Coronary Atherosclerosis
Interventions: DEVICE: Cardiac MRI|DRUG: Contrast|DRUG: Beta blocker
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nebulized Fentanyl in Patients With Mild to Moderate Interstitial Lung Disease and Chronic Dyspnea
Status: COMPLETED
Conditions: Interstitial Lung Disease
Interventions: DRUG: Fentanyl Citrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fetal Scalp Stimulation Versus Fetal Blood Sampling in Labour
Status: TERMINATED
Conditions: Intrapartum Fetal Distress
Interventions: DIAGNOSTIC_TEST: Fetal Blood Sampling (FBS)|DIAGNOSTIC_TEST: digital Fetal Scalp Stimulation (dFSS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Intrathecal Atropine to Prevent Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea
Interventions: DRUG: Intrathecal atropine|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Alveolar Bone Preservation Using Photobiomodulation Combined With Grafting With Scaffold Biomaterial
Status: COMPLETED
Conditions: Extracting Own Teeth|Bone Substitutes
Interventions: PROCEDURE: extraction|RADIATION: low level laser therapy|BIOLOGICAL: Plenum® OSShp and Plenum® Guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Hansoh (HS)-10502 in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Ovarian Cancer|Breast Cancer|Pancreatic Cancer|Prostatic Cancer|Colorectal Cancer
Interventions: DRUG: HS-10502
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Safety Study With Adalimumab in Chinese Subjects With Mild Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: adalimumab|BIOLOGICAL: adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combining Stellate Ganglion and T2 and T3 Radiofrequency Ablation on Post-mastectomy Complex Regional Pain Syndrome
Status: RECRUITING
Conditions: Stellate Ganglion|Radiofrequency Ablation|Complex Regional Pain Syndromes|Mastectomy
Interventions: PROCEDURE: Radiofrequency stellate ganglion block using ultrasound guidance (SGB)|PROCEDURE: Radiofrequency thoracic (T2, T3) paravertebral block under fluoroscopic guidance (TPVB)|PROCEDURE: Combined radiofrequency of stellate ganglion block plus thoracic T2, T3 paravertebral block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Dose-dense Doxorubicin and Cyclophosphamide Followed by Paclitaxel With Bevacizumab in Operable Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Paclitaxel|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomised Phase II, Cetuximab in Combination With 5FU and Cisplatin or Carboplatin Versus Cetuximab in Combination With Paclitaxel and Carboplatin for Treatment of Patients With Metastatic Squamous Cell Carcinoma of the Head and Neck
Status: UNKNOWN
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antepartum Betamethasone Treatment for Prevention of Respiratory Distress in Infants Born by Elective Cesarean Section
Status: TERMINATED
Conditions: Respiratory Distress Syndrome, Newborn
Interventions: DRUG: Betamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Low Level Laser Therapy to Treat Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DEVICE: Erchonia MLS|DEVICE: Placebo Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Most Closely HLA-Matched CTLs for Relapsed Epstein Barr Virus(EBV)-Associated Diseases
Status: COMPLETED
Conditions: Hodgkin Lymphoma|Non-Hodgkin Lymphoma|Lymphoproliferative Disorder|Nasopharyngeal Carcinoma|Leiomyosarcoma|Severe Chronic Active EBV (SCAEBV)
Interventions: BIOLOGICAL: LMP specific T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: WallFlex Biliary Fully Covered (FC) Chronic Pancreatitis Study
Status: COMPLETED
Conditions: Biliary Stricture
Interventions: DEVICE: WallFlex™ Biliary RX Fully Covered Stent System RMV|DEVICE: Commercially available Plastic Stent Per Investigator preference
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Lifestyle Intervention for Improving Functional Health Outcomes Using N-of-1 Tent-Umbrella-Bucket Design
Status: COMPLETED
Conditions: Health, Subjective|Gastrointestinal Dysfunction|Cardiovascular Risk Factor|Autoimmune Diseases|Dental Diseases|Hormone Disturbance|Neurocognitive Dysfunction
Interventions: DIETARY_SUPPLEMENT: Supplements and/or medical foods|BEHAVIORAL: Behavioral change support program|OTHER: Food plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mechanisms of Panic Disorders Treatment
Status: UNKNOWN
Conditions: Panic Disorder|Agoraphobia|Panic Attacks
Interventions: BEHAVIORAL: Cognitive Behavioural Therapy (CBT)|BEHAVIORAL: Cognitive Behavioural Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Markers of Esophageal Function in Adults
Status: ENROLLING_BY_INVITATION
Conditions: Dysphagia
Interventions: OTHER: Clinical measure questionnaires|DIAGNOSTIC_TEST: EESG|DIAGNOSTIC_TEST: MESG|DIAGNOSTIC_TEST: High resolution manometry (HRM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Preoperative Nutritional Intervention in Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Malnutrition
Interventions: DIETARY_SUPPLEMENT: Nutritional Supplement|BEHAVIORAL: Preoperative Dietitian Consult|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deslorelin Combined With Low-Dose Add-Back Estradiol and Testosterone in Preventing Breast Cancer in Premenopausal Women Who Are at High Risk for This Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: brca1 Mutation Carrier|brca2 Mutation Carrier|Breast Cancer
Interventions: BIOLOGICAL: therapeutic estradiol|DRUG: deslorelin|DRUG: therapeutic testosterone|PROCEDURE: therapeutic conventional surgery|OTHER: active surveillance|PROCEDURE: quality-of-life assessment|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Post-market Clinical Follow-up Study of Alcon PRECISION1™ Spherical and PRECISION1™ for Astigmatism Soft Contact Lenses
Status: NOT_YET_RECRUITING
Conditions: Refractive Errors
Interventions: DEVICE: Verofilcon A spherical soft contact lenses|DEVICE: Verofilcon A toric soft contact lenses
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cetuximab and Envafolimab Plus mFOLFOXIRI as First-line Treatment for RAS/BRAF Wild-type, MSS, Unresectable Left-side Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Cetuximab + Envafolimab + mFOLFOXIRI|DRUG: Cetuximab + mFOLFOX6/FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Patient Position on Computerized Tomography Guided Celiac Trunk Neurolysis
Status: COMPLETED
Conditions: Upper Abdominal Malignancy
Interventions: DEVICE: Double needle celiac neurolysis (DNCN)|DEVICE: Single needle celiac neurolysis (SNCN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Diabetic Self-care Education at Primary Health Care in Saudi Arabia: A Pragmatic Randomized Trial in Tabuk
Status: COMPLETED
Conditions: Self-care|Preventive Care|Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Diabetic care Information, education, and communication intervention will be delivered by relevant and trained health animators working in chronic care clinic.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, PK Profile, and Symptom Response of a 7-Day Dosing With 25 mg or 50 mg Daily of REL-1017 in MDD
Status: COMPLETED
Conditions: Depressive Disorder, Major|Depressive Disorder, Treatment-Resistant
Interventions: DRUG: REL-1017|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ovariopexy for Adhesion Prevention After Laparoscopic Removal of Endometriosis of the Pelvic Side Wall or the Ovary
Status: COMPLETED
Conditions: Endometriosis|Adhesion|Surgery
Interventions: PROCEDURE: ovariopexy|PROCEDURE: placebo operation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Low Voltage-Directed Catheter Ablation for Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation - Symptomatic
Interventions: PROCEDURE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dietary Supplement for Mood Symptoms in Early Postpartum: A Double Blind Randomized Placebo Controlled Trial
Status: COMPLETED
Conditions: Postpartum Blues|Healthy
Interventions: DIETARY_SUPPLEMENT: Motherwell|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of Selexipag in Healthy Male Participant
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Selexipag matrix tablet|DRUG: Selexipag encapsulated pellets|DRUG: Selexipag Immediate-release (IR) tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triamcinolone Acetonide in Patients With Serous Pigment Epithelial Detachment
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: PROCEDURE: Subtenon injection of 40 mg triamcinolone acetonide|PROCEDURE: Intravitreal injection of 4 mg triamcinolone acetonide|DIAGNOSTIC_TEST: Visometry|DIAGNOSTIC_TEST: Fluorescent angiography|DIAGNOSTIC_TEST: Refractometry|DIAGNOSTIC_TEST: Slit lamp examination|DIAGNOSTIC_TEST: Ophthalmoscopy|DIAGNOSTIC_TEST: OKT|DIAGNOSTIC_TEST: IOP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Thrombo-embolic Complications After Endovascular Treatment of Unruptured Intracranial Aneurysms
Status: COMPLETED
Conditions: Unruptured Intracranial Aneurysms
Interventions: OTHER: diffusion-weighted MRI and clinical examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigation of Huatuo Zaizao Pill in Treating Phlegm and Blood-stasis Blocking Collaterals Pattern of Ischemic Stroke Patients: Study Protocol for a Randomized Controlled Trial
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: DRUG: HuaTuo Zaizao pill|OTHER: basic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Human Trial to Evaluate the Efficacy and Safety of Fermented Turmeric in Subjects Showing Mild Hepatic Injury
Status: COMPLETED
Conditions: Mild Hepatic Injury
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Fermented turmeric
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Use of Belladonna and Opium Suppository in the Treatment of Postoperative Stent Pain
Status: COMPLETED
Conditions: Nephrolithiasis
Interventions: DRUG: Belladonna and Opium|OTHER: Placebo suppository
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Sofosbuvir and Daclatasvir Combo in COIVD-19 Patients in Egypt
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Sofosbuvir 400 MG/ Daclatasvir 60mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Safety and Efficacy of Travacom in Patients With Uncontrolled Intraocular Pressure
Status: COMPLETED
Conditions: Uncontrolled Intraocular Pressure
Interventions: DRUG: Travacom
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of an Intermediate CPB in Neck Surgeries.
Status: RECRUITING
Conditions: Anesthesia|Thyroid|Neck|Bupivacaine
Interventions: PROCEDURE: Cervical Plexus Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Double Blinded Comparison of Ceftazidime and Meropenem in Severe Melioidosis
Status: UNKNOWN
Conditions: Melioidosis
Interventions: DRUG: Meropenem|DRUG: Ceftazidime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Drug up Titration by Nurses Specialized in Heart Failure (HF) Patients
Status: COMPLETED
Conditions: Heart Failure
Interventions: OTHER: Heart Failure (HF) nurse up-titration|OTHER: Heart Failure (HF) cardiologist up-titration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: BAY94-8862 Dose Finding Trial in Subjects With Chronic Heart Failure and Mild (Part A) or Moderate (Part B) Chronic Kidney Disease
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: BAY94-8862|DRUG: BAY94-8862|DRUG: BAY94-8862|DRUG: BAY94-8862|DRUG: Placebo|DRUG: Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Study of ONO-4819CD for Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: Rivenprost (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of Patients With Chronic Hepatitis C Undergoing Treatment With PegIntron and Rebetol in Clinical Practice in Belgium (Study P05494)(WITHDRAWN)
Status: WITHDRAWN
Conditions: Hepatitis C, Chronic|Hepatitis C
Interventions: BIOLOGICAL: PegIntron (peginterferon alfa-2b; SCH 54031)|DRUG: Rebetol (ribavirin; SCH 18908)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Basket Study of Pyrotinib Maleate for HER2-Postive Solid Tumor
Status: UNKNOWN
Conditions: Solid Tumor|HER2 Gene Mutation|HER-2 Gene Amplification|HER-2 Protein Overexpression
Interventions: DRUG: Pyrotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Elective Clipping of Colonic Diverticula
Status: COMPLETED
Conditions: Diverticular Disease
Interventions: PROCEDURE: Endoscopic clipping of diverticula|PROCEDURE: Follow-up colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Examination of Idiopathic Hypogonadotropic Hypogonadism (IHH)and Kallmann Syndrome (KS)
Status: COMPLETED
Conditions: Kallmann Syndrome|Hypogonadotropic Hypogonadism|GnRH Deficiency
Interventions: DRUG: gonadotropin releasing hormone (GnRH)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of GLP-1 on Glucose Uptake in the Brain and Heart in Healthy Men
Status: COMPLETED
Conditions: Type 2 Diabetes|Stroke|Myocardial Infarction
Interventions: DRUG: glucagon-like-peptide-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Evolution of Quality of Life in Relation to Naso-sinus Symptomatology Under Treatment With CFTE Modulators in Children Aged 6 to 11 Years With Cystic Fibrosis With Compatible Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: Cystic Fibrosis
Interventions: DRUG: CFTR modulators
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Shockwave Therapy Versus LIPUS on Mandibular Fracture Bone Healing
Status: COMPLETED
Conditions: Mandibular Fractures
Interventions: PROCEDURE: inter maxillary fixation with shockwave therapy|PROCEDURE: Inter maxillary fixation and exposure to low intensity pulsed|PROCEDURE: Inter maxillary fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CMV IGG Antibodies in Semen as a Predictor for Blood Testis Barrier Damage
Status: UNKNOWN
Conditions: Male Infertility
Interventions: DIAGNOSTIC_TEST: Blood test (CMV IGG, Anti sperm antibody, Testosterone levels)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 1 Study of the Combination of Rogaratinib With Copanlisib in Patients With Fibroblast Growth Factor Receptor (FGFR)-Positive, Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Advanced or Metastatic Solid Tumor
Interventions: DRUG: Rogaratinib (BAY1163877)|DRUG: Copanlisib (BAY80-6946)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive and Behavioral Effects of Sleep Restriction in Adolescents With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Healthy Sleep Duration|BEHAVIORAL: Shortened Sleep Duration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: CBPR Strategies to Increase Colorectal Cancer Screening in Ohio Appalachia
Status: COMPLETED
Conditions: Colon Cancer|Rectal Cancer
Interventions: BEHAVIORAL: "Get Behind your health"|BEHAVIORAL: Peaches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Efficacy and Safety of Palonosetron in Preventing the Gastrointestinal Reactions Induced by 3-day Highly Emetogenic Chemotherapy
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Palonosetron|DRUG: Granisetron|DRUG: Dexamethasone|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial Comparing C-Brace to Knee Ankle Foot Orthosis (KAFO)/Stance Control Orthosis (SCO)
Status: COMPLETED
Conditions: Pareses, Lower Extremity
Interventions: DEVICE: C-Brace|DEVICE: KAFO/SCO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Evaluating 3-year Disease Free Survival in Patients With Locally Advanced Rectal Cancer Treated With Chemoradiation Plus Induction or Consolidation Chemotherapy and Total Mesorectal Excision or Non-operative Management
Status: ACTIVE_NOT_RECRUITING
Conditions: Rectal Cancer
Interventions: DRUG: Oxaliplatin (OXAL)|DRUG: 5-Fluorouracil (5-FU)|DRUG: Leucovorin|DRUG: Capecitabine (Xeloda®)|RADIATION: intensity modulated radiotherapy (IMRT)|BEHAVIORAL: Quality of Life Questionnaires|PROCEDURE: DRE-Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Desflurane and Its Effect on Postoperative Morbidity and Mortality in Patients Undergoing Thoracic Surgery
Status: COMPLETED
Conditions: Thoracic Surgery
Interventions: DRUG: Desflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Four Reconstructions After Total Gastrectomy
Status: UNKNOWN
Conditions: Gastric Cancer|Nutrition
Interventions: PROCEDURE: R-Y reconstruction after total gastrectomy|PROCEDURE: P-Y reconstruction after total gastrectomy|PROCEDURE: Pouch reconstruction after total gastrectomy|PROCEDURE: P-I reconstruction after total gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Temporally Feathered Radiation Therapy (TFRT) for Head and Neck Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: RADIATION: Temporally Feathered Radiation Therapy (TFRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Spironolactone Combined With Captopril and Carvedilol for the Treatment of Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: spironolactone captopril carvedilol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Light Therapy to Treat Cancer-related Side Effects
Status: RECRUITING
Conditions: Breast Cancer|Circadian Rhythms|Fatigue|Sleep Disturbance|Cognitive Impairment|Inflammatory Response|Depression
Interventions: DEVICE: Light Glasses (Experimental)|DEVICE: Light Glasses (Comparison)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Icotinib Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors
Status: COMPLETED
Conditions: Vestibular Schwannoma|Neurofibromatosis Type 2
Interventions: DRUG: Icotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease
Status: RECRUITING
Conditions: Early Alzheimer's Disease
Interventions: DRUG: CT1812|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dipyridamole for Immune Activation in HIV
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Dipyridamole|DRUG: Placebo, then Dipyridamole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CD19 T-CAR for Treatment of Children and Young Adults With r/r B-ALL
Status: ACTIVE_NOT_RECRUITING
Conditions: B-cell Acute Lymphoblastic Leukemia|Acute Lymphocytic Leukemia, Pediatric
Interventions: BIOLOGICAL: Chimeric Antigen Receptor T-Cell Therapy|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Tocilizumab|DRUG: Cytarabine|DRUG: Etoposide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microsurgical Clipping and Endovascular Embolization Comparative Prospective Randomized Trial
Status: NOT_YET_RECRUITING
Conditions: Ruptured Cerebral Aneurysm|Unruptured Cerebral Aneurysm
Interventions: PROCEDURE: Microsurgical clipping|PROCEDURE: Endovascular embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-erythroid Effects of Erythropoietin on Cognitive Function and Exercise Capacity in Humans
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Erythropoietin (Epoetin beta)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Acral Lentiginous Melanoma|Central Nervous System Melanoma|Clinical Stage IV Cutaneous Melanoma AJCC v8|Leptomeningeal Neoplasm|Melanocytoma|Metastatic Lung Non-Small Cell Carcinoma|Metastatic Melanoma|Metastatic Mucosal Melanoma|Metastatic Uveal Melanoma|Stage IV Lung Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Lumbar Puncture|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Nivolumab|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cost-efficacy Between ART and Composite Resin Restorations in Primary Molars
Status: UNKNOWN
Conditions: Dental Caries
Interventions: PROCEDURE: ART using Fuji IX|PROCEDURE: Conventional Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduction of Oxalate and Inflammation by Hemodiafiltration vs. Hemodialysis
Status: COMPLETED
Conditions: Chronic Kidney Disease Requiring Chronic Dialysis
Interventions: PROCEDURE: Hemodialysis|PROCEDURE: Hemodiafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multicentre Radial Artery Patency Study: Results of Patency Beyond 5 Years After Coronary Artery Bypass Surgery
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Radial Artery and Saphenous Vein Grafts Randomized to either right coronary or left circumflex coronary artery territories
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Frequency of Total Body Water Measurements by Bioelectrical Impedance Analysis to Prevent Intradialytic Hypotension
Status: COMPLETED
Conditions: Intradialytic Hypotension|End Stage Renal Disease on Dialysis
Interventions: DEVICE: Bioelectrical Impedance Analysis (BIA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessing Accuracy of Clinical Diagnosis and Lesion Location in Acute Neurological Deficits - How Good Are Neurologists?
Status: UNKNOWN
Conditions: Stroke Syndrome|Stroke Hemorrhagic|Stroke, Acute|Strokes Thrombotic|Emergencies|Diagnostic Self Evaluation
Interventions: OTHER: No study specific interventions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Dose Camptothecin-11 (CPT-11) in Recurrent Unresectable Malignant Glioma
Status: COMPLETED
Conditions: Malignant Glioma
Interventions: DRUG: Irinotecan (Camptosar, CPT-11)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Participants With Untreated Extensive-Stage Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: Tiragolumab|DRUG: Atezolizumab|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Tiragolumab Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Orthodontic Patient Experience of Intraoral Scans Versus Alginate Impressions
Status: COMPLETED
Conditions: Orthodontic Patient Experience
Interventions: PROCEDURE: Intraoral scan|PROCEDURE: Alginate impressions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mini S Feasibility Study With Shockwave Medical Mini S Peripheral IVL System
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Shockwave Medical Mini S Peripheral IVL Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: CF101 Therapy in Patients With Moderate-to-severe Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: CF101 2mg|DRUG: CF101 3mg|DRUG: Apremilast 30mg|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised Study of Consolidation CTRT Versus Observation After First Line Chemotherapy in Advanced Gallbladder Cancer
Status: UNKNOWN
Conditions: Gallbladder Cancer Unresectable
Interventions: RADIATION: chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Home-based Inspiratory Muscle Training in Patients With IPF
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis|IPF
Interventions: DEVICE: Inspiratory Muscle Training (IMT)|DEVICE: Sham IMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Zhen Qi Shen Capsule Combined With Yu Yi Kang on Breast Cancer and Lung Cancer Patients With Chemotherapy
Status: UNKNOWN
Conditions: Breast Cancer|Lung Cancer
Interventions: DIETARY_SUPPLEMENT: zhen qishen capsule and Oral Supplement of Yuyikang|DIETARY_SUPPLEMENT: zhen qishen capsule placebo and Oral Supplement of Yuyikang placebo|RADIATION: chemotherapy|OTHER: nutrition education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antioxidant Supplementation in Pregnant Women With Low Antioxidant Status
Status: COMPLETED
Conditions: Preeclampsia
Interventions: DRUG: Vitamin C 1000mg and E 400IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The ELDORADO (Eligard®, Docetaxel and Radiotherapy) Study
Status: UNKNOWN
Conditions: Prostatic Neoplasms
Interventions: DRUG: Docetaxel|DRUG: Leuprolide Acetate (Eligard®)|RADIATION: Intensity-Modulated Radiotherapy|RADIATION: Intensity-Modulated Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Folic Acid and Creatine as Therapeutic Approaches for Lowering Blood Arsenic
Status: COMPLETED
Conditions: High Blood Arsenic Due to Chronic Arsenic Exposure
Interventions: OTHER: Placebo|DIETARY_SUPPLEMENT: folic acid|DIETARY_SUPPLEMENT: folic acid|DIETARY_SUPPLEMENT: creatine|DIETARY_SUPPLEMENT: creatine + folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Thyroid Hormone for Remyelination in Multiple Sclerosis (MS): A Safety and Dose Finding Study
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Liothyronine sodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Solution for the Treatment of Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Cyclosporine 5% solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Overcoming Barriers to HIV/AIDS Care and ART Initiation
Status: COMPLETED
Conditions: Engagement in HIV Care
Interventions: BEHAVIORAL: Expedited CD4 testing|BEHAVIORAL: Supplemental peer counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Re-invitation to Screening Colonoscopy: a Randomized Study
Status: UNKNOWN
Conditions: Colorectal Cancer|Screening|Patient Participation
Interventions: BEHAVIORAL: Re-invitation letter|BEHAVIORAL: Invitation to educational meeting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of an Oral Anti-TNF Antibody in Patients With Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: AVX 470|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib/II Clinical Study of GH21 Capsules Combined With Osimertinib Mesylate Tablets in Patients With NSCLC
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer With EGFR Mutation
Interventions: DRUG: GH21|DRUG: Tagrisso
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monitoring of Anti-SARS-CoV-2 (COVID 19) and Encapsulated Vaccination Patients With Thalassemic and Falcemic Syndromes
Status: ACTIVE_NOT_RECRUITING
Conditions: SARS-CoV-2 Infection, Thalasemmie, SCD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Hemodynamic Effect of Dexmedetomidine in Scheduled Outpatient Surgery
Status: RECRUITING
Conditions: Anesthesia|Dexmedetomidine|Hemodynamics|Ambulatory Care
Interventions: DRUG: Dexmedetomidine|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: RElevance of UltraSonography for Assessing Salivary Gland Involvement in Systemic Sclerosis (SSc)
Status: COMPLETED
Conditions: Systemic Sclerosis
Interventions: DIAGNOSTIC_TEST: Minor Salivary gland Biopsy|DIAGNOSTIC_TEST: ARFI|DIAGNOSTIC_TEST: MSG US
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Determinants of Bone and Muscle Quality and Strength in Obesity With and Without Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 2|Obesity|Body Weight|Bone Diseases, Metabolic|Fractures, Bone|Osteoporotic Fractures|Osteoporosis|Quality of Life|Fall|Musculoskeletal Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inhaled Nebulised S(+)-Ketamine for Postoperative Analgesia
Status: WITHDRAWN
Conditions: Pain, Postoperative
Interventions: DRUG: Ketamine first AB|DRUG: Placebo first BA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate a Contact Lens Lubricating and Rewetting Drop
Status: COMPLETED
Conditions: Dry Eye
Interventions: DEVICE: Lubricating and Rewetting Drops|DEVICE: AMO Blink Contacts Lubricant Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Revefenacin Peak Inspiratory Flow Rate (PIFR) Study in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease, COPD|Low Peak Inspiratory Flow Rate (PIFR)
Interventions: DRUG: Revefenacin|COMBINATION_PRODUCT: Spiriva Handihaler®|DRUG: Placebo for Revefenacin|DRUG: Placebo for Spiriva Handihaler®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of BMN 110 in Pediatric Patients < 5 Years of Age With Mucopolysaccharidosis IVA (Morquio A Syndrome)
Status: COMPLETED
Conditions: Mucopolysaccharidosis IVA|Morquio A Syndrome|MPS IVA
Interventions: DRUG: BMN 110
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction Therapy for Lupus Nephritis With no Added Oral Steroids: A Trial Comparing Oral Corticosteroids Plus Mycophenolate Mofetil (MMF) Versus Obinutuzumab and MMF
Status: RECRUITING
Conditions: Lupus Nephritis|Systemic Lupus Erythematosus (SLE)
Interventions: DRUG: Obinutuzumab administration|DRUG: Administration of Methylprednisolone + Prednisone + Mycophenolate mofetil|DRUG: Administration of methylprednisolone, paracetamol and dexchlorpheniramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Alopecia Areata (AA) With Dupilumab in Patients With and Without Atopic Dermatitis (AD)
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: Dupilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
Status: RECRUITING
Conditions: Obesity|Overweight
Interventions: DRUG: LY3305677|DRUG: LY3841136|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: L Rhamnosus ATCC 53103 & L Reuteri DSM 29063 Compared With L Rhamnosus ATCC 53103 for Preventing AAD in Children
Status: UNKNOWN
Conditions: Antibiotic-associated Diarrhea
Interventions: DIETARY_SUPPLEMENT: Lactobacillus rhamnosus ATCC 53103 & Lactobacillus reuteri DSM 29063|DIETARY_SUPPLEMENT: L rhamnosus ATCC 53103
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Subjective Well-being and Tolerability of Quetiapine XR to Risperidone
Status: COMPLETED
Conditions: Schizophrenic Disorders
Interventions: DRUG: Quetiapine XR|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT