pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Prospective Randomized Endovascular Therapy in Multiple Sclerosis - PREMiSE
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DEVICE: Selective Venography followed by therapeutic balloon angioplasty|OTHER: Control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: In-utero Hematopoietic Stem Cell Transplantation for the Treatment of Fetuses With Bart's Hydrops Fetalis Syndrome
Status: RECRUITING
Conditions: Haemoglobin Barts Hydrops
Interventions: PROCEDURE: in-utero HSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of HEC93077 in Chinese Healthy Subjects and HUA Patients With Single or Multiple Dosing
Status: RECRUITING
Conditions: Gout
Interventions: DRUG: HEC93077|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Decitabine Alone or in Combination With Venetoclax, Gilteritinib, Enasidenib, or Ivosidenib as Maintenance Therapy for the Treatment of Acute Myeloid Leukemia in Remission
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Decitabine and Cedazuridine|DRUG: Enasidenib|DRUG: Gilteritinib|DRUG: Ivosidenib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Eluting Balloon for Prevention of Constrictive Remodeling
Status: TERMINATED
Conditions: Coronary Disease|Diabetes Mellitus
Interventions: DEVICE: Paclitaxel coated balloon catheter|DEVICE: uncoated balloon catheter "sprinter legend"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corneal Collagen Crosslinking and Intacs for Keratoconus and Ectasia
Status: ACTIVE_NOT_RECRUITING
Conditions: Keratoconus|Corneal Ectasia
Interventions: DRUG: Riboflavin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PINS Stimulator System for Deep Brain Stimulation of the Nucleus Accumbens to Treat Severe Opioid Addiction
Status: UNKNOWN
Conditions: Opioid Addiction
Interventions: DEVICE: Deep brain stimulation：PINS Stimulation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Genosvid Diagnostic Test for Early Detection of COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: OTHER: exhaled breath sampling|OTHER: exhaled breath sampling|OTHER: exhaled breath sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial Evaluating Combined Chemotherapy in Patients With Metastatic Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: Gemcitabine - Trastuzumab - Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Of Antidepressants On Sexual Functioning In Adults
Status: COMPLETED
Conditions: Major Depressive Disorder (MDD)
Interventions: DRUG: Extended-release Bupropion Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the MBio Combined Syphilis/HIV Point-of-Care Diagnostic Test
Status: COMPLETED
Conditions: HIV|Syphilis
Interventions: DEVICE: MBIO POC combined HIV syphilis test ( SnapEsi)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pemetrexed Plus a Comparator Versus a Combination of 2 Comparators in First-Line Treatment of Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emergency Ketamine Treatment of Suicidal Ideation
Status: UNKNOWN
Conditions: Depression|Suicidal Ideation|Suicidal Impulses
Interventions: DRUG: Intranasal Ketamine|DRUG: Intranasal Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Bioequivalence Study Of Xanax Extended Release Tablets From Two Different Manufacturing Sites
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Xanax XR tablets 3 mg (sourced from Caugus)|DRUG: Xanax XR tablets 3 mg (sourced from Barceloneta)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nutraceutical on Hyperuricemia
Status: COMPLETED
Conditions: Hyperuricemia
Interventions: DRUG: Uricemin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COgNitive FuncTional Therapy+ for Chronic Low Back paIn
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: BEHAVIORAL: Cognitive Functional Therapy+ pathway|BEHAVIORAL: Interdisciplinary pain management pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot of a Prebiotic and Probiotic Trial in Young Infants With Severe Acute Malnutrition
Status: COMPLETED
Conditions: Severe Acute Malnutrition
Interventions: OTHER: Bifidobacterium infantis|OTHER: Bifidobacterium infantis with prebiotic Lacto-N-neotetraose [LNnT]|OTHER: Placebo (Lactose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: GP2013 Treatment in Patients With Active Rheumatoid Arthritis, Previously Treated With Rituxan® or MabThera®
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: GP2013 - A Proposed biosimilar rituximab|BIOLOGICAL: Originator rituximab - Rituxan ® or MabThera ®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Human Convalescent Plasma for High Risk Children Exposed or Infected With SARS-CoV-2 (COVID-19)
Status: COMPLETED
Conditions: SARS-CoV-2 Infection
Interventions: BIOLOGICAL: Anti-SARS-CoV-2 Human Convalescent Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Neostigmine and Glycopyrrolate
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injuries|Constipation|Fecal Incontinence|Neurogenic Bowel
Interventions: DRUG: Combination of Neostigmine and Glycopyrrolate|DEVICE: I-Box by Dynatronics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carotid Artery Corrected Flow Time Measured by Ultrasonography as a Predictor of Hypotension After Induction of General Anesthesia
Status: WITHDRAWN
Conditions: General Anesthesia Induction for Elective Surgery
Interventions: PROCEDURE: ultrasonographic measurement of corrected flow time(FTc) in carotid artery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Overcoming Stigma and Improving Outcomes for SUDs Through Education, Engagement, and Empowerment
Status: COMPLETED
Conditions: Opioid Use Disorder
Interventions: BEHAVIORAL: Overcoming and Addressing Stigma in Substance Use Disorders (OASIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Alvocidib, Cytarabine, and Mitoxantrone Hydrochloride or Cytarabine and Daunorubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Secondary Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: alvocidib|DRUG: daunorubicin hydrochloride|DRUG: mitoxantrone hydrochloride|DRUG: cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Migraine Inducing Effects and Changes in Brain Haemodynamics of PGI2
Status: UNKNOWN
Conditions: Headache|Migraine|Vasodilatation
Interventions: DRUG: Prostacyclin, PGI2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study To Evaluate The Safety, Tolerability And Plasma Drug Levels Following A Single Dose Of PF-04995274 In Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-04995274|DRUG: PF-04995274|DRUG: PF-04995274|DRUG: PF-04995274
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Probiotics In Colorectal Cancer Patients
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: PROCEDURE: Probiotics (La1, BB536)|BIOLOGICAL: probiotics (La1, BB536)|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Enteral Nutrition in Nasopharyngeal Carcinoma Survivors With Swallowing Disorders
Status: NOT_YET_RECRUITING
Conditions: Dysphagia
Interventions: DEVICE: Nasogastric Tube Feeding|DEVICE: Intermittent Oral-esophageal Tube Feeding|BEHAVIORAL: comprehensive rehabilitation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose-finding Study of Four Dosage Levels of an H7N9 Influenza Vaccine in Adults Between Ages of 18 Years and 65 Years
Status: COMPLETED
Conditions: H7N9 Influenza
Interventions: BIOLOGICAL: H7N9c low dose with adjuvant|BIOLOGICAL: H7N9c medium dose with adjuvant|BIOLOGICAL: H7N9c high dose with adjuvant|BIOLOGICAL: H7N9c high dose without adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Rib Raising for Post-operative Ileus
Status: COMPLETED
Conditions: Intestinal Pseudo-Obstruction|Manipulation, Osteopathic|Postoperative Care|Postoperative Nausea and Vomiting|Postoperative Complications|Osteopathic Medicine
Interventions: PROCEDURE: Rib raising and lumbar release|PROCEDURE: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Albuterol SPIROMAX® in Adult and Adolescent Patients With Exercise-Induced Bronchoconstriction (EIB)
Status: COMPLETED
Conditions: Exercise-Induced Bronchoconstriction (EIB)
Interventions: DRUG: Albuterol Spiromax|DRUG: Placebo Spiromax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II/III Trial to Evaluate the Efficacy and Safety of QL1706 in Patients With Nasopharyngeal Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: QL1706|DRUG: Carrelizumab|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Retigabine Extended Release (XR) Formulation in Healthy Adult Japanese and Caucasian Subjects
Status: WITHDRAWN
Conditions: Epilepsy, Partial
Interventions: DRUG: Retigabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: 40Hz tACS in Treating Cognitive Function and Modulating Neurophysiology of Patients With Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: DEVICE: active tACS|DEVICE: sham tACS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Autism of Aripiprazole and Risperidone Treatment (BAART)
Status: COMPLETED
Conditions: Autistic Disorder
Interventions: DRUG: Aripiprazole|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Vital Capacity
Status: TERMINATED
Conditions: Respiration Disorders|Neuromuscular Disease
Interventions: DEVICE: measures of assisted vital capacity by a mechanical insufflation/exsufflation (Cough Assist®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficiency of Everolimus for the Treatment of Kidney Transplanted Patients Presenting a Missing Self-induced NK-mediated Rejection
Status: RECRUITING
Conditions: Kidney Transplant Failure and Rejection
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SHR-1701 Combined With Fluzoparib in Lung Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: SHR-1701 Combined With Fluazopalil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sentinel Node Biopsy in Breast Cancer: Omission of Axillary Clearance After Macrometastases. A Randomized Trial.
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: Omission of axillary clearance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pan-European Study on Minimally Invasive Versus Open Pancreatoduodenectomy in High-volume Centers
Status: COMPLETED
Conditions: Pancreatic Neoplasms|Pancreas Cyst|Pancreas Cancer
Interventions: PROCEDURE: Minimally invasive pancreatoduodenectomy|PROCEDURE: Open pancreatoduodenectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Left Atrial Appendage Occlusion Versus New Oral Anticoagulants for Stroke Prevention in Patients With Non-valvular Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DEVICE: left atrial appendage occlusion|DRUG: New oral anticoagulants
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison of Patients Receiving a Total Knee Replacement With Robotic Assistance or With Conventional Instrumentation
Status: WITHDRAWN
Conditions: Arthritis|Osteoarthritis|Knee|Joint Diseases|Musculoskeletal Diseases|Rheumatic Diseases
Interventions: DEVICE: NAVIO/CORI Surgical System|PROCEDURE: Non-robotic conventional instrumentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Change-a Multi-center Chronic Thromboembolic Pulmonary Hypertension （CTEPH） Database in China
Status: RECRUITING
Conditions: Chronic Thromboembolic Pulmonary Hypertension
Interventions: PROCEDURE: pulmonary endarterectomy or balloon pulmonary angioplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Social Cognition in Patient With Type 1 or Type 2 Narcolepsy Versus Patients With Idiopathic Hypersomnia
Status: RECRUITING
Conditions: Narcolepsy|Social Cognition
Interventions: OTHER: Questionary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Temozolomide Versus Dacarbazine in Stage IV Metastatic Melanoma (Study P03267)
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Temozolomide|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Vinorelbine and Cisplatin and Concurrent Radiotherapy After Induction Chemotherapy in Locally Advanced NSCLC.
Status: COMPLETED
Conditions: Lung Neoplasm
Interventions: DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2a Study to Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of AG011 in Ulcerative Colitis
Status: COMPLETED
Conditions: Moderately Active Ulcerative Colitis
Interventions: BIOLOGICAL: AG011|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OPTIMISER Registry - A Prospective Cohort Study to Describe the OPTIMal Management and Outcomes of PatIents PreSEnting With Acute MyocaRdial Infarction
Status: RECRUITING
Conditions: Myocardial Infarction|Myocardial Ischemia|STEMI|NSTEMI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Symptomatic Treatment of Acute Gastroenteritis
Status: COMPLETED
Conditions: Gastroenteritis|Vomiting|Acute Gastroenteritis
Interventions: DRUG: Ondansetron|DRUG: Domperidone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microbiota Modification for Immuno-oncology in Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: EXL01
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microvascular Dysfunction in Nonischemic Cardiomyopathy: Insights From CMR Assessment of Coronary Flow Reserve
Status: TERMINATED
Conditions: Hypertrophic Cardiomyopathy|Non-ischemic Dilated Cardiomyopathy|Microvascular Ischaemia of Myocardium
Interventions: DRUG: Regadenoson|DRUG: Adenosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing the Hemodiafiltration On-line and Conventional Hemodialysis in Terms of Cost-benefit
Status: COMPLETED
Conditions: Chronic Renal Failure|Hemodialysis
Interventions: DEVICE: conventional hemodialysis|DEVICE: hemodiafiltration On-line
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention for Reducing Psychiatric Symptoms and Metabolic Variables in Patients With Diabetes Mellitus (DM)
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Problem Solving Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Periodontal Therapy on Mental Health Parameters
Status: RECRUITING
Conditions: Periodontitis|Depression
Interventions: PROCEDURE: Standard periodontal therapy (steps 1 & 2)|PROCEDURE: supragingival debridement with anesthesia (step 1)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Evaluation of the Ivory Dentin Graft Device
Status: COMPLETED
Conditions: Deficiency of Alveolar Ridge (Disorder)|Alveolar Bone Grafting|Mandibular Prosthesis User
Interventions: DEVICE: Graft Matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pazopanib and Everolimus in PI3KCA Mutation Positive/PTEN Loss Patients
Status: COMPLETED
Conditions: Advanced Cancers|Solid Tumors
Interventions: DRUG: Pazopanib|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reverse Total Shoulder Arthroplasty Versus Open Reduction Internal Fixation of 3&4 Part Proximal Humerus Fractures
Status: TERMINATED
Conditions: Closed Fracture Proximal Humerus, Four Part
Interventions: PROCEDURE: Fracture repair|PROCEDURE: Fracture repair with joint replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AURA-LV: Aurinia Urinary Protein Reduction Active - Lupus With Voclosporin (AURA-LV)
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: DRUG: Voclosporin High Dose|DRUG: Voclosporin Low Dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study for Validating the Equivalence of Bloomlife MFM-Pro to Clinical Standard-of-care for Antepartum Fetal Monitoring
Status: COMPLETED
Conditions: Fetal Monitoring
Interventions: DEVICE: Bloomlife MFM-Pro
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Probiotic on Gut Microbiome and Bacterial Translocation in Healthy Asian Volunteers
Status: UNKNOWN
Conditions: Dysbiosis
Interventions: DRUG: Colonic lavage with polyethylene glycol|DIETARY_SUPPLEMENT: Probiotic|DRUG: Antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-modal Neuroimaging in Children With Cerebral Palsy or Brachial Plexus Birth Palsy
Status: UNKNOWN
Conditions: Cerebral Palsy|Brachial Plexus; Injury, Newborn
Interventions: DEVICE: Magnetoencephalography (MEG)|DEVICE: Electroencephalography (EEG)|DEVICE: Transcranial Magnetic Stimulation (TMS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Statins To Treat Adult Cystic Fibrosis
Status: WITHDRAWN
Conditions: Cystic Fibrosis|Systemic Inflammation
Interventions: DRUG: Simvastatin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Adverse Events and Change in Disease Activity When Intravenous (IV) Infusion of ABBV-927 is Administered in Combination With IV Modified FOLFIRINOX (mFFX) With or Without IV Budigalimab Compared to mFFX in Adult Participants With Untreated Pancreatic Cancer Metastasis
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: ABBV-927|DRUG: Budiglimab|DRUG: modified FOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasonic Versus Monopolar Energy-based Surgical Device in Colpotomy
Status: COMPLETED
Conditions: Gynecologic Diseases
Interventions: PROCEDURE: Laparoscopic colpotomy by ultrasonic ESD|PROCEDURE: Laparoscopic colpotomy by monopolar ESD|DEVICE: Monopolar ESD|DEVICE: Ultrasonic ESD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Hemodynamic Effects of Two Colloid Therapies in Post-operative Patients Undergoing Pancreaticoduodenectomy
Status: COMPLETED
Conditions: Pancreaticoduodenectomy
Interventions: DRUG: 6% hydroxyethyl starch 130/0.4|DRUG: Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1/2a Study of 23ME-00610 in Patients With Advanced Solid Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor|Clear Cell Renal Cell Carcinoma|Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma|Neuroendocrine Tumors|MSI-H Cancer|Cancer With A High Tumor Mutational Burden|Extensive-stage Small-cell Lung Cancer
Interventions: DRUG: 23ME-00610
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study: Postoperative Pain Reduction by Pre Emptive N-Acetylcysteine
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Acetyl cysteine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Bone Marrow Harvest and Transplant for Sensorineural Hearing Loss
Status: SUSPENDED
Conditions: Sensorineural Hearing Loss
Interventions: GENETIC: Autologous Bone Marrow Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retinal Laser by Multi-spot Photocoagulator and Driving Eligibility
Status: COMPLETED
Conditions: Proliferative Diabetic Retinopathy
Interventions: PROCEDURE: Pan retinal Photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy Study of Fluzone® Vaccine Combined With Different Doses of JVRS-100 Adjuvant
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluzone vaccine with JVRS-100 adjuvant|BIOLOGICAL: Fluzone vaccine|BIOLOGICAL: Fluzone vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy Study of NuCel® in Patients Undergoing Fusion of the Lumbar Spine
Status: COMPLETED
Conditions: Intervertebral Disc Disease|Intervertebral Disc Degeneration|Spondylosis|Spondylolisthesis|Spinal Stenosis
Interventions: OTHER: NuCel with Autograft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prazosin for Alcohol Dependence and Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Alcohol Abuse|Posttraumatic Stress Disorder
Interventions: DRUG: Prazosin|DRUG: Placebo medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of Transcranial Direct Current Stimulation (tDCS) of the Primary Motor Cortex (M1) or the Prefrontal Cortex Combined With Aerobic Activity for Alleviation of Fibromyalgia Symptoms.
Status: NOT_YET_RECRUITING
Conditions: Fibromyalgia|Electric Shock
Interventions: DEVICE: Direct Stimulation Prefrontal Cortex|DEVICE: Shame cortex stimulation|DEVICE: Direct Stimulation to Motor Cortex|BEHAVIORAL: erobic physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Effectiveness Study of the Tixel Device, (Fractional Peri-orbital Wrinkles Treatment ) Compared With Laser
Status: TERMINATED
Conditions: Wrinkle
Interventions: DEVICE: Tixel|DEVICE: Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of Live Attenuated Vaccine Against Varicella Without Gelatin
Status: COMPLETED
Conditions: Chickenpox|Zoster
Interventions: BIOLOGICAL: vaccine without gelatin|BIOLOGICAL: vaccine with gelatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 3 Trial of Autologous Dendritic Cell Immunotherapy Plus Standard Treatment of Advanced Renal Cell Carcinoma
Status: TERMINATED
Conditions: Advanced Renal Cell Carcinoma|Renal Cell Carcinoma|Metastatic Renal Cell Carcinoma
Interventions: DRUG: Standard Treatment|BIOLOGICAL: AGS-003
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abdominal Hernia in Cirrhotic Patients: Surgery or Conservative Treatment?
Status: COMPLETED
Conditions: Liver Cirrhosis|Hernia|Ascites|Surgery
Interventions: PROCEDURE: Elective Hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Flibanserin for the Treatment of Hypoactive Sexual Desire Disorder in Postmenopausal Women
Status: COMPLETED
Conditions: Sexual Dysfunctions, Psychological
Interventions: DRUG: flibanserin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: UARK 89-001 Phase II Study of Intensive "TOTAL THERAPY" For Untreated or Minimally Treated Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: VAD|DRUG: High-Dose cyclophosphamide|PROCEDURE: Hemopoietic stem cell procurement|DRUG: EDAP|PROCEDURE: Autologous Hemopoietic Stem Cell Transplant 1|PROCEDURE: Autologous Hemopoietic Stem Cell Transplant 2|DRUG: Maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fetoscopic Endoluminal Tracheal Occlusion
Status: RECRUITING
Conditions: Congenital Diaphragmatic Hernia
Interventions: DEVICE: Fetoscopic Endoluminal Tracheal Occlusion (FETO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Choice and Outcomes for ESRD: Evidence From the First Year of a Nationwide Randomized Evaluation
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: OTHER: Payment adjustment for home dialysis and transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Safety and Efficacy Study of Intravenous E5564 in Patients With Severe Sepsis
Status: COMPLETED
Conditions: Sepsis|Shock, Septic|Sepsis Syndrome|Septicemia|Infection
Interventions: DRUG: E5564
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of SHR-1210 in Combination With Pemetrexed and Carboplatin in Subjects With Non-squamous NSCLC
Status: COMPLETED
Conditions: Lung Neoplasms|Carcinoma, Non-Small-Cell Lung|Respiratory Tract Neoplasms|Thoracic Neoplasms|Lung Diseases|Respiratory Tract Disease|Neoplasms by Site|Neoplasm, Bronchial|Carcinoma, Bronchogenic
Interventions: BIOLOGICAL: SHR-1210|DRUG: Carboplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Repetitive Transcranial Magnetic Stimulation in Cancer Patients With Chemotherapy-Induced Peripheral Neuropathy
Status: UNKNOWN
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: DEVICE: Real repetitive transcranial magnetic stimulation|DEVICE: Sham repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: EWOC-1 Trial: Carboplatin +/- Paclitaxel in Vulnerable Elderly Patients With Stage III-IV Advanced Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Paclitaxel + Carboplatin every 3 weeks|DRUG: Carboplatin monotherapy every 3 weeks|DRUG: Weekly Paclitaxel and Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study in Subjects With Mild to Moderate Psoriasis.
Status: UNKNOWN
Conditions: Mild to Moderate Psoriasis
Interventions: DRUG: AKP02/AKVANO cutaneous spray (calcipotriol 50 μg/g + betamethasone 0.5 mg/g/ AKVANO)|DRUG: Enstilar Topical Product (calcipotriol 50 μg/g + betamethasone 0.5 mg/g)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Herceptin® (Trastuzumab) in Combination With Arimidex® (Anastrozole) an Aromatase Inhibitor Compared to Arimidex® Alone in Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: trastuzumab (Herceptin®)|DRUG: anastrazole (Arimidex®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and Operability of Using the New Tissue Containment System During Laprascopic Hysterectomy
Status: UNKNOWN
Conditions: Gynecologic Surgery
Interventions: DEVICE: the new tissue containment system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A 6-month, Randomized, Open-label, Patient OutComes, Safety and Tolerability Study of Fingolimod (FTY720) 0.5 mg/Day vs. Comparator in Patients With Relapsing Forms of Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing Forms of Multiple Sclerosis
Interventions: DRUG: Fingolimod|DRUG: Standard MS DMTs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-Based Lymphedema Care Program (HBLCP) in Improving Lymphedema Self-Care in Head and Neck Cancer Survivors
Status: TERMINATED
Conditions: Head and Neck Cancer|Lymphedema
Interventions: BEHAVIORAL: Home-based Lymphedema Care Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Androgen Deprivation Therapy and Vorinostat Followed by Radical Prostatectomy in Treating Patients With Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Adenocarcinoma|Stage I Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer|Stage III Prostate Cancer
Interventions: DRUG: Bicalutamide|DRUG: Goserelin Acetate|OTHER: Laboratory Biomarker Analysis|DRUG: Leuprolide Acetate|PROCEDURE: Therapeutic Conventional Surgery|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood-Brain Barrier Disruption (BBBD) for Liquid Biopsy in Subjects With GlioBlastoma Brain Tumors
Status: RECRUITING
Conditions: Glioblastoma|Glioma|Liquid Biopsy
Interventions: DEVICE: Focused Ultrasound (Exablate Model 4000)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase I Study to Evaluate the Safety and Pharmacokinetics of CT-P41 and EU-approved Prolia in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Male Subjects
Interventions: BIOLOGICAL: CT-P41|BIOLOGICAL: EU-approved Prolia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Modelling of Energy Expenditure From Heart Rate, Accelerometry and Other Physiological Parameters
Status: COMPLETED
Conditions: Computer Simulation|Energy Expenditure|Energy Metabolism
Interventions: DEVICE: calorimetric chamber|DEVICE: Free living conditions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vinorelbine-ifosfamide Versus Gefitinib for EGFR Gene Mutation Negative Non-small Cell Lung Cancer Patients
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer|Effects of Chemotherapy
Interventions: DRUG: Gefitinib group|DRUG: Vinorelbine, Ifosfamide, Mesna
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of Dry Needling Treatment in Patients Diagnosed With Greater Trochanteric Pain Syndrome
Status: RECRUITING
Conditions: Greater Trochanteric Pain Syndrome
Interventions: OTHER: Dry needling group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Methylnaltrexone (Relistor) on Digestion and Tolerance to Tube Feeding in Patients Treated With Opiates
Status: WITHDRAWN
Conditions: Tube Feeding
Interventions: DRUG: Methylnaltrexone|DRUG: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Antidepressant on Postsynaptic Signal Transduction in Serotonergic System of Depressed Patients
Status: UNKNOWN
Conditions: Depression
Interventions: DRUG: antidepressant response|DRUG: antidepressant non-response
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Myoinositol Treatment of Spermatozoa on in Vitro Fertilization Outcome
Status: COMPLETED
Conditions: Couple Sterility
Interventions: DIETARY_SUPPLEMENT: Myo-inositol|OTHER: untreated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Application of Two Anti-angiogenesis Drugs Combined With Chemotherapy in Advanced Colorectal Cancer Under the Background of Precision Medical
Status: UNKNOWN
Conditions: Colorectal Neoplasms
Interventions: DRUG: Two Anti-angiogenesis Drugs（Endostar and Thalidomide）|DRUG: Pure chemotherapy（Xelox）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Calypso Guided High Precision Stereotactic Ablative Radiosurgery for Lung TUmours Using Real-Time Tumour Tracking & Respiratory Gating
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer Stage I|Lung Cancer Stage II|Lung Cancer, Nonsmall Cell|Lung Cancer Recurrent|Lung Cancer Stage IV
Interventions: DEVICE: Real-Time Position Transponder Beacons
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BRAF Inhibitor, LGX818, Utilizing a Pulsatile Schedule in Patients With Stage IV or Unresectable Stage III Melanoma Characterized by a BRAFV600 Mutation
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: LGX818
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating 111In-Panitumumab for Nodal Staging in Head and Neck Cancer
Status: SUSPENDED
Conditions: Head and Neck Cancer
Interventions: DRUG: 111I-n panitumumab|PROCEDURE: Single photon emission computed tomography/computed tomography (SPECT/CT) scans
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant
Status: RECRUITING
Conditions: Obesity|Malignant Neoplasm
Interventions: OTHER: Interview|OTHER: Media Intervention|OTHER: Questionnaire Administration|OTHER: Scale Device|BEHAVIORAL: Telephone-Based Intervention|OTHER: Text Message
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prospective Multicenter Cohort Study Evaluating the Incidence and Risk Factors for Problem Gambling Among Young Adults With First-episode Psychosis
Status: RECRUITING
Conditions: Gambling Disorder|Psychotic Disorders
Interventions: DRUG: Dopamine partial agonists|OTHER: Psychiatric comorbidities|OTHER: Sex|OTHER: Gender|OTHER: Socioeconomic status|OTHER: Gambling history
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Three Different Doses of Intrathecal Morphine for Analgesia After Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section|Spinal Anesthesia|Postoperative Analgesia
Interventions: DRUG: 80 mcg intrathecal morphine|DRUG: 120 mcg intrathecal morphine|DRUG: 160 mcg intrathecal morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Long-Acting Mesalamine on Post-Infective Irritable Bowel Syndrome- A Pilot Study
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Mesalamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of SBRT/Olaparib Followed by Pembrolizumab/Olaparib in Gastric Cancers
Status: RECRUITING
Conditions: Gastric Cancer|GastroEsophageal Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Olaparib|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine and 5-year Outcome in Elderly Patients After Surgery
Status: COMPLETED
Conditions: Aged|Operative|Delirium|Dexmedetomidine|Mortality|Long-term Survivors
Interventions: DRUG: dexmedetomidine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Saline Eustress in Plant Food (ESEPF)
Status: COMPLETED
Conditions: Healthy Diet
Interventions: DIETARY_SUPPLEMENT: Placebo comparator: Control group. To the control group was assigned lettuce without any change in salinity but with the same characteristic of eustress lettuce (soil, water, harvesting time).|DIETARY_SUPPLEMENT: Experimental: Eustress group. To the intervention Eustress group was assigned the eustress lettuce.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Statin Adjunct Therapy Among ART-treated Adults in Sub-Saharan Africa: Atorvastatin and Rosuvastatin Equivalence Trial
Status: UNKNOWN
Conditions: HIV Infection
Interventions: DRUG: ART, Atorvastatin|DRUG: ART, Rosuvastatin|DRUG: ART, No statin|DRUG: Healthy-HIV-negative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maximum Tolerated Dose, Safety and Efficacy of Docetaxel / Cisplatin + STI571
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Docetaxel, Cisplatin and STI571|DRUG: Docetaxel|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Intermittent Pneumoperitoneum Scheme of Work Breaks in Complex Laparoscopic Surgery
Status: COMPLETED
Conditions: Stress Physiology|Staff Work Load|Artificial Pneumoperitoneum|Anuria
Interventions: BEHAVIORAL: IPP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Hepatitis B Vaccine for Non-responders
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: HBVaxPro|BIOLOGICAL: HBAI20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assess the Influence of a High-fat Meal on the Relative Bioavailability Of Two Formulations of Risedronate
Status: COMPLETED
Conditions: Bioavailability
Interventions: DRUG: Risedronate|DRUG: Risedronate|DRUG: Risedronate|DRUG: Risedronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Treatment of Keloid Scar by Autologous Platelet Rich Plasma Obtained With RgenKit-BCT
Status: COMPLETED
Conditions: Keloid
Interventions: DEVICE: Autologous Platelet Rich Plasma obtained with RegenKit®-BCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT