pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of Gene Polymorphisms and Normal Tissue Radiation Injury in Patients Treated for Breast, Prostate, Brain, Lung, and Head and Neck Cancers
Status: UNKNOWN
Conditions: Breast Cancer|Glioma|Prostate Cancer|Carcinoma, Squamous Cell|Carcinoma, Non-Small-Cell-Lung|Head and Neck Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Everolimus MICE-regimen in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: cytarabine|DRUG: etoposide|DRUG: everolimus|DRUG: idarubicin|DRUG: mitoxantrone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intern Health Study: 2020 Cohort Micro-Randomized Trial
Status: COMPLETED
Conditions: Telemedicine
Interventions: BEHAVIORAL: Intern Health Study competition-related mobile notification|BEHAVIORAL: Intern Health Study mobile app|BEHAVIORAL: Intern Health Study mobile app competition scoreboard and history
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant PD-1 Antibody Plus Apatinib or Chemotherapy for Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prometa Protocol for Alcohol Dependence
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: Flumazenil and Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACHAT-STUDY, Alternative Treatment of Chronic Globus Sensations
Status: COMPLETED
Conditions: Globus|Deglutition Disorders
Interventions: RADIATION: Beamer Ablation (Argon Plasma Coagulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Dose-finding Study for SAR442168 in Relapsing Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing Multiple Sclerosis
Interventions: DRUG: SAR442168|DRUG: Placebo|DRUG: Locally approved intravenous contrast medium for contrast enhanced magnetic resonance imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Utility of Nexium in Chronic Cough and Reflux Disease
Status: COMPLETED
Conditions: Cough|GERD
Interventions: DRUG: Esomeprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Community-Engaged Bidirectional Pandemic Crisis and Emergency Risk Communication With COVID-19 Vaccine Messages to Minority Populations
Status: COMPLETED
Conditions: Vaccine Preventable Disease
Interventions: OTHER: Educational, culturally appropriate COVID-19 messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preoperative Vitamin D for Post-thyroidectomy Hypocalcemia
Status: WITHDRAWN
Conditions: Hypocalcemia
Interventions: DRUG: Vitamin D|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Rheo-Erythrocrine Dysfunction as a Biomarker for RIC Treatment in Acute Ischemic Stroke
Status: COMPLETED
Conditions: Stroke, Acute|Ischemic Stroke|Cerebrovascular Disorders|Central Nervous System Diseases
Interventions: DEVICE: Remote Ischemic Conditioning|DEVICE: Sham Remote Ischemic Conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Predictors of Clinical and Radiological Response to Gamma-Knife Radiosurgery in the Treatment of Intermediate Ventral Nucleus of the Thalamus (VIM) Thalamotomy Tremor.
Status: UNKNOWN
Conditions: Severe Disabling Tremor
Interventions: DEVICE: gamma knife radiosurgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Study to Compare the Bioavailability of Two Clobetasol Propionate 0.05% Topical Foams
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Clobetasol Propionate 0.05% Foam-Reference Product|DRUG: Clobetasol Propionate 0.05% Foam-Test product
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Exploratory Efficacy Study of SF0166 in the Treatment of Neovascular Age-Related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: SF0166 Topical Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Zoledronic Acid in Men on Androgen Deprivation Therapy for Prostate Cancer With Preexisting Osteoporosis
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Dose the Saline Reduce the Mucus Production When Water Exchange Colonoscopy is Used?
Status: COMPLETED
Conditions: Colon Mucous|Colonoscopy
Interventions: OTHER: CO2|OTHER: Water|OTHER: 50% saline|OTHER: 25% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Safety and Immunogenicity Study to Assess TDV, a Live Attenuated Tetravalent Vaccine for Prevention of Dengue Fever
Status: COMPLETED
Conditions: Dengue Fever
Interventions: BIOLOGICAL: TDV - Low Dose|BIOLOGICAL: TDV - High Dose|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Chemotherapy and Pelvic Hypofractionated Radiation Followed by Surgery Cervical Cancer
Status: RECRUITING
Conditions: Cervix Cancer
Interventions: RADIATION: Standard radiotherapy|RADIATION: hypofractionated radiotherapy|PROCEDURE: Radical hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mcgrath Videolaryngoscope Versus Macintosh Laryngoscope in Patients With Manual In-line Stabilization
Status: UNKNOWN
Conditions: Anesthesia, General
Interventions: DEVICE: Group ML|DEVICE: Group DL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess BMS-986458 Alone and in Combination With Anti-lymphoma Agents in Relapsed/Refractory Non-Hodgkin Lymphomas
Status: RECRUITING
Conditions: Relapsed/Refractory Non-Hodgkin Lymphoma
Interventions: DRUG: BMS-986458|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Neratinib In Combination With Temsirolimus In Subjects With Solid Tumors
Status: COMPLETED
Conditions: Neoplasms|Malignant Carcinoma
Interventions: DRUG: Neratinib|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anal HPV Tests in Screening for Cell Changes in the Anus in Patients With HIV
Status: COMPLETED
Conditions: Anal Cancer|HIV Infection|Human Papilloma Virus Infection
Interventions: PROCEDURE: comparison of screening methods|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Phase I/II Trial of Bevacizumab, Pemetrexed and Erlotinib in Elderly Patients With Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Bevacizumab|DRUG: Erlotinib|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Bioavailability of Various Formulations of GDC-0134 in Healthy Female Participants of Non-Childbearing Potential
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: GDC-0134 F09 Formulation|DRUG: GDC-0134 F15 Formulation|DRUG: GDC-0134 F16 Formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epigenetic Biomarker for Advanced Osteosarcoma Using Famitinib and Camrelizumab
Status: UNKNOWN
Conditions: Drug Resistance to Famitinib and Camrelizumab|Biomarkers for Efficacy and Toxicity
Interventions: DIAGNOSTIC_TEST: 5hmc testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study Among Type 2 Diabetes Patients Investigating the Effects of Computerized Cognitive and Physical Activity Programs Combined or Single (DIASCOP)
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Physical activity|BEHAVIORAL: cognitive training|BEHAVIORAL: combined physical and cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics Study of Ianalumab in Chinese Participants With Autoimmune Diseases
Status: NOT_YET_RECRUITING
Conditions: Sjogren Disease|Systemic Lupus Erythematosus
Interventions: DRUG: ianalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Ocular Pharmacokinetics After 1 Drop of T1225 0.5, 1 and 1.5% in 48 Healthy Volunteers
Status: COMPLETED
Conditions: Eye Infections, Bacterial
Interventions: DRUG: Azithromycin (T1225)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Ventilator Trigger Sensitivity Adjustment Versus Threshold Inspiratory Muscle Training on Arterial Blood Gases
Status: RECRUITING
Conditions: Guillain-Barre Syndrome
Interventions: OTHER: Threshold inspiratory muscle trainer or ventilator pressure setting inspiratory muscle training techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Smartphone-based Aftercare for Inpatients With Anorexia Nervosa
Status: UNKNOWN
Conditions: Anorexia Nervosa
Interventions: BEHAVIORAL: Recovery Record aftercare|BEHAVIORAL: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Early Switching From Intravenous to Oral Antibiotics Therapy
Status: COMPLETED
Conditions: Skin and Subcutaneous Tissue Infection
Interventions: PROCEDURE: IV-to-PO conversion of antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early DHA Supplementation in Very Low Birth Weight Infants
Status: COMPLETED
Conditions: Prematurity
Interventions: OTHER: Low dose PUFA|OTHER: High dose PUFA|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Amantadine + rTMS as a Neurotherapeutic for Disordered Consciousness
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DEVICE: rTMS|DRUG: Amantadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Prostate Adenocarcinoma|Stage IVB Prostate Cancer AJCC v8
Interventions: BIOLOGICAL: Anti-STEAP1 CAR T-cells|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|PROCEDURE: Computed Tomography|DRUG: Cyclophosphamide|PROCEDURE: Echocardiography|DRUG: Enzalutamide|DRUG: Fludarabine|PROCEDURE: Leukapheresis|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Multigated Acquisition Scan|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Model for Predicting the Efficacy of Conversion Therapy for Patients With Colorectal Cancer Liver Metastases by the Detection of 5-hydroxymethylcytosine (5-hmC) in Plasma Cell-free DNA
Status: UNKNOWN
Conditions: Colorectal Cancer With Liver Metastases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Influence of Working Length Methods in the Performance of Pulpectomies in Primary Teeth
Status: UNKNOWN
Conditions: Endodontically Treated Teeth
Interventions: OTHER: Pulpectomies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pathophysiological Implications of the Incretin Hormones in Maturity Onset of Diabetes of the Young (MODY)
Status: COMPLETED
Conditions: Maturity-onset Diabetes of the Young
Interventions: OTHER: Oral Glucose Tolerance Test (OGTT)|OTHER: iso glycaemic intravenous (iv) glucose infusion (IIGI)|DIETARY_SUPPLEMENT: Meal test|OTHER: Sitagliptin|OTHER: Incretin effect on sulphonyl urea treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Advanced Gastrointestinal Cancer in a Phase I/II Trial With Modified Autologous MSC_apceth_101
Status: TERMINATED
Conditions: Advanced Gastrointestinal Cancer
Interventions: DRUG: MSC_apceth_101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Which Analgesia is Better for Proximal Femoral Fractures?
Status: UNKNOWN
Conditions: Proximal Femur Fracture
Interventions: PROCEDURE: Fascia iliaca block|PROCEDURE: combined LFCN block with PENG block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Magnesium Sulfate in Obese Preeclamptics
Status: COMPLETED
Conditions: Preeclampsia
Interventions: DRUG: Magnesium sulfate 4g loading dose, 1g/hr infusion|DRUG: Magnesium sulfate 6g loading dose, 2g/hr infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexpramipexole Dose-Ranging Biomarker Study in Subjects With Eosinophilic Asthma
Status: COMPLETED
Conditions: Eosinophilic Asthma|Asthma
Interventions: DRUG: Dexpramipexole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Dental Implants Placed in Preserved and Non-preserved Post-extraction Ridges
Status: WITHDRAWN
Conditions: Dental Implant Failed|Platelet-rich Fibrin|Alveolar Rege Preservation|Alveolar Bone Loss
Interventions: DEVICE: Dental implant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Remo-Wax® Oil (RWO) in Subjects With Isolated Itching of the External Ear Canal
Status: COMPLETED
Conditions: Itching
Interventions: DEVICE: Remo-Wax® Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Matuzumab in Combination With Pemetrexed for the Treatment of Advanced Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer|Non Small Cell Lung Carcinoma
Interventions: DRUG: Pemetrexed|DRUG: Matuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerability and Pharmacokinetics of Metformin and Metformin Extended Release (ER)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: metformin ER|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COM701 in Combination With BMS-986207 and Nivolumab in Subjects With Advanced Solid Tumors.
Status: COMPLETED
Conditions: Endometrial Neoplasms|Ovarian Cancer|Solid Tumor|Head and Neck Cancer
Interventions: DRUG: COM701 in combination with BMS-986207 and nivolumab.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Nonsurgical Periodontal Therapy Verses Oral Hygiene Instructions on Patients With Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: PROCEDURE: Nonsurgical periodontal therapy|PROCEDURE: Oral hygiene instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transumbilical Single Incision Versus Conventional Three Incisions Laparoscopic Appendicectomy
Status: COMPLETED
Conditions: Acute Appendicitis
Interventions: PROCEDURE: transumbilical single incision laparoscopic appendicectomy|PROCEDURE: conventional laparoscopic appendicectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Without Cerebral perfusıon Under Deep Hypothermic Circulatory Arrest (DHCA) (18 Deegres) the Comparison of the Undergoing Proximal Aortic Surgery Patients Preoperative and Postoperative Diffusion Magnetic Resonance Imaging's and Neuron Specific Enolase Enzyms Levels.
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Infarct|Neurological Morbidity|Neurological Complication
Interventions: PROCEDURE: DHCA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Use of FNA and FNB in the Optimization of EUS-assisted Tissue Sampling
Status: COMPLETED
Conditions: Neoplasms
Interventions: DEVICE: EUS-guided fine needle biopsy sampling (EUS-FNB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Shingrix in Patients With Rheumatic Diseases: a Double-blind Placebo-controlled RCT
Status: NOT_YET_RECRUITING
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: recombinant subunit herpes zoster vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Convenience, Safety and Efficacy of Follitropin Alfa Liquid Pen Compared With Follitropin Beta Liquid Pen
Status: COMPLETED
Conditions: Infertility|Ovulation Induction
Interventions: DRUG: Follitropin alfa liquid formulation|DRUG: Follitropin beta liquid formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Reactogenicity of GlaxoSmithKline (GSK) Biologicals' IPV Vaccine (PoliorixTM) in Toddlers
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: PoliorixTM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Specialized Healthcare Service for BPD Patients: Athens Trial
Status: RECRUITING
Conditions: Other Mental Conditions
Interventions: BEHAVIORAL: Specific Therapy Program for Personality Disorders|OTHER: Treatment As Usual (TAU) Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3305677 in Participants With Obesity Or Overweight
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DRUG: LY3305677|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Aldesleukin With or Without Vaccine Therapy in Treating Patients With Stage IV Melanoma
Status: COMPLETED
Conditions: Stage IV Melanoma
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: allogeneic large multivalent immunogen vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PACAP27 Headache Properties in Migraine Without Aura Patients
Status: COMPLETED
Conditions: Migraine Without Aura
Interventions: DRUG: PACAP27|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase II, Single-Center, Oral Panobinostat in Combination With Lenalidomide and Dexamethasone in Multiple Myeloma (MM)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Panobinostat|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative and Opioid Free Anesthesia
Status: TERMINATED
Conditions: Anesthesia|Opioid-Related Disorders
Interventions: DRUG: Dexmedetomidine|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on The Use of Autologous Bone Marrow Stem Cells in Amyotrophic Lateral Sclerosis (Extension CMN/ELA)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: PROCEDURE: Laminectomy and bone marrow stem cells transplantation|PROCEDURE: Intrathecal infusion of autologous bone marrow stem cells|PROCEDURE: Intrathecal infusion of placebo (saline solution).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan and Temozolomide in Treating Patients With Breast Cancer Who Have Received Previous Treatment for Brain Metastases
Status: COMPLETED
Conditions: Breast Cancer|Metastatic Cancer
Interventions: DRUG: irinotecan hydrochloride|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplantation for Patients With Hematologic Malignancies
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemias|Acute Myelocytic Leukemia|Chronic Myeloid Leukemia|Juvenile Myelomonocytic Leukemia|Myelodysplastic Syndrome|Hemoglobinuria, Paroxysmal|Non-Hodgkin Lymphoma
Interventions: PROCEDURE: Allogeneic Stem Cell Transplantation|DRUG: Chemotherapy and antibodies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of APL-1501 Extended Release Capsules Compared to APL-1202 Immediate Release Tablets in Healthy Volunteers
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: APL-1202|DRUG: APL-1501
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility/Acceptability of Attentional-Control Training in Survivors
Status: RECRUITING
Conditions: Pediatric Cancer|Pediatric ALL|Pediatric Brain Tumor|Attention Difficulties|Cognitive Deficit in Attention
Interventions: DEVICE: EndeavorRx|OTHER: Control video game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interscalene Block Versus Infraclavicular Block Plus Suprascapular Nerve Block
Status: COMPLETED
Conditions: Shoulder Injury
Interventions: PROCEDURE: Interscalene block|PROCEDURE: Infraclavicular-suprascapular block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetic and Safety Study of Travoprost 0.004% in Pediatric Glaucoma Patients
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: Travoprost ophthalmic solution, 0.004% (new formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Umbilical Cord/Placenta-Derived Mesenchymal Stem Cells to Treat Myelodysplastic Syndromes
Status: UNKNOWN
Conditions: Myelodysplastic Syndromes
Interventions: OTHER: Human umbilical cord-derived MSCs|OTHER: cyclosporine A (CsA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photoallergy Potential of Dapsone Gel in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: dapsone gel|DRUG: dapsone gel vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Dabigatran Etexilate (Pradaxa®) During Haemodialysis
Status: COMPLETED
Conditions: Cardiovascular Diseases|Kidney Failure, Chronic
Interventions: DRUG: Dabigatran etexilate|DRUG: Dabigatran etexilate|DRUG: Dabigatran etexilate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Bioavailability of Belumosudil (KD025) in Healthy Male Subjects
Status: COMPLETED
Conditions: Bioavailability
Interventions: DRUG: Belumosudil Tablet|DRUG: Belumosudil Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Recovery Profile After TIVA Between Remimazolam With Flumazenil and Propofol
Status: COMPLETED
Conditions: Anesthesia, Intravenous
Interventions: DRUG: remimazolam-based TIVA|DRUG: propofol-based TIVA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Measuring Wounds Found on the Outside of the Body Surface
Status: COMPLETED
Conditions: External Wounds Measured for Length by Width Using a Ruler
Interventions: DEVICE: "gold standard" LxW manual ruler measurement technique|DEVICE: WMMS ImageReview software's LxW measurement technique|DEVICE: WMMS ImageReview software's Visual External Wound Trace|DEVICE: WMMS ImageReview software's External Wound Trace Overlay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Mochudi Prevention Project ART Protocol
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: highly active antiretroviral therapy: Lopinavir/Ritonavir, Lamivudine, Zidovudine, Efavirenz, Tenofovir Disoproxil Fumarate, Emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Long-term Safety and Efficacy Outcome Study Comparing Children Previously Enrolled in Study ROPP-2008-01 for the Prevention of Retinopathy of Prematurity (ROP)
Status: COMPLETED
Conditions: Retinopathy of Prematurity (ROP)
Interventions: DRUG: rhIGF-1/rhIGFBP-3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flu-Bu-Mel Based Conditioning Regimen for Patients With Lymphoid Malignancies Undergoing Allo-HSCT
Status: RECRUITING
Conditions: Lymphoid Neoplasm
Interventions: DRUG: Flu-Bu-Mel-E
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Involving Subjects Over 70 Years of Age With Non Small-cell Lung Cancer of Stage IV and Comparing a "Classical" Strategy of Treatment Allocation, With an"Optimized" Strategy Allocating the Same Treatments
Status: COMPLETED
Conditions: Non Small-cell Lung Cancer
Interventions: PROCEDURE: Dual-agent therapy or docetaxel alone or best supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Investigate the Effectiveness of a Topical Cosmetic Formulation DA-OTC-002
Status: COMPLETED
Conditions: Hair Diseases|Alopecia|Hair Loss
Interventions: COMBINATION_PRODUCT: DA-OTC-002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Effects of Co-Administration of Alcohol on the Absorption of Oxycodone From a Proprietary Controlled-Release Formulation
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Test formulation administered with water|DRUG: Test formulation administered with 20% ethanol|DRUG: Test formulation administered with 40% ethanol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Billroth-II Modified Versus Roux-en-Y After Distal Gastrectomy for Gastric Cancer
Status: RECRUITING
Conditions: Gastric Cancer|Distal Gastrectomy
Interventions: PROCEDURE: Distal gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effects of Sedentary Behaviour and Moderate Exercise on Glucose Tolerance and Insulin Sensitivity
Status: TERMINATED
Conditions: Sedentary Lifestyle|Insulin Sensitivity|Glucose Metabolism
Interventions: OTHER: Activity/Moderate Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Chemotherapy and Biological Therapy in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: Recombinant Interferon Alfa|DRUG: Cytarabine|DRUG: Omacetaxine Mepesuccinate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FOLFOX Plus Regorafenib in Patients With Unresectable or Metastatic Esophagogastric Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: Regorafenib|DRUG: 5-Fluorouracil|DRUG: Leucovorin|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A U.S Post Approval Study Evaluating the SYNERGY XLV (MEGATRON) Stent System
Status: COMPLETED
Conditions: Atherosclerosis|Heart Diseases, Coronary|Coronary Artery Disease|Cardiovascular Diseases
Interventions: DEVICE: SYNERGY XLV (Megatron) Coronary Stent System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 4 Study to Assess the Effect of Bisoprolol on Glycemic Level in Type II Diabetic Subjects With Suboptimal Blood Pressure Control
Status: COMPLETED
Conditions: Hypertension|Diabetes Mellitus, Type II
Interventions: DRUG: Bisoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Transcutaneous Auricular Vagus Nerve Stimulation on Radiotherapy-Related Neuropathic Pain
Status: UNKNOWN
Conditions: Neuropathic Pain|Radiotherapy Side Effect
Interventions: DEVICE: Transcutaneous Auricular Vagus Nerve Stimulation(TaVNS)|DEVICE: Sham Transcutaneous Auricular Vagus Nerve Stimulation(SS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Range Finding Study of Fedovapagon in Men With Nocturia
Status: COMPLETED
Conditions: Nocturia
Interventions: DRUG: fedovapagon 1 mg|DRUG: fedovapagon 2 mg|DRUG: fedovapagon 4 mg|DRUG: Placebo ( sugar pill)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Immunogenicity & Safety of an Investigational Influenza Vaccine (H1N1) in Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GSK investigational vaccine GSK2340272A|BIOLOGICAL: GSK investigational vaccine GSK2340269A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Salicylic Acid Peels Combined With 4% Hydroquinone in the Treatment of Moderate to Severe Melasma in Hispanic Women
Status: COMPLETED
Conditions: Melasma
Interventions: DRUG: 20-30% Salicylic Acid peels to the right side of the face|DRUG: 20-30% Salicylic Acid peels to the left side of the face
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Marginal Periosteal Pedicle Flap - Platelet Rich Fibrin Barriers in Treating Periodontal Intrabony Defects
Status: COMPLETED
Conditions: Periodontal Pocket
Interventions: PROCEDURE: Regenerative therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Dose Finding Study of Remifentanil and Propofol for Lumbar Punctures in Children
Status: COMPLETED
Conditions: Hematologic Diseases|Neoplasms
Interventions: DRUG: Remifentanil|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Technology Enhanced Adolescent Mental Health (TEAM)
Status: RECRUITING
Conditions: Nonsuicidal Self Injury|Alcohol Abuse|Vagus Nerve Stimulation
Interventions: DEVICE: Non-invasive Transcutaneous Nerve Stimulation (tVNS)|DEVICE: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study: Safety of a Customized MRI System for Neonatal Imaging
Status: COMPLETED
Conditions: Safety of a Customized NICU MRI System
Interventions: DEVICE: GE OPTIMA MR430s with HDX/GE Electronics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Blood Flow Restriction Training on Middle-aged People With Multiple Sclerosis.
Status: COMPLETED
Conditions: Sclerosis, Multiple
Interventions: OTHER: Blood Flow Restriction training with Oclussion Cuff.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Chemo-Radiotherapy With Peripheral Blood Progenitor Cell Rescue for Children With Advanced Neuroblastoma and Sarcomas
Status: COMPLETED
Conditions: Neuroblastoma|Ewings Sarcoma|Non-rhabdomyosarcoma Soft Tissue Sarcoma
Interventions: DRUG: Vincristine|DRUG: Cyclophosphamide|DRUG: Adriamycin|DRUG: Etoposide (VP-16)|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Melphalan|DRUG: Ifosfamide|DRUG: G-CSF (granulocyte-colony stimulating factor)|DRUG: Mesna
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Home Care Planned According to Orem in Patients With Primary Brain Tumor and Their Caregivers
Status: COMPLETED
Conditions: Primary Brain Tumor|Caregiver Burden|Self Care
Interventions: OTHER: home care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Long Term Follow-Up of Rotator Cuff Tear Patients Treated With Integrated Complementary and Alternative Medicine
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: DRUG: Herbal medicine|PROCEDURE: Chuna manual medicine|PROCEDURE: Pharmacopuncture|PROCEDURE: Acupuncture|PROCEDURE: Electroacupuncture|PROCEDURE: Cupping|PROCEDURE: Herbal hot pack|PROCEDURE: Physical therapy|PROCEDURE: Other intervention(s)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Esthetic Outcomes of Immediately Placed Implants Receiving Immediate Provisionalization and Delayed Restoration
Status: COMPLETED
Conditions: Tooth Diseases|Tooth Extraction|Dental Implant
Interventions: DEVICE: Test (immediate restoration)|DEVICE: Control: delayed restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Endotracheal Tube Fixation Methods on Hemodynamic Parameters During Endotracheal Suction
Status: COMPLETED
Conditions: Cardiac Surgery
Interventions: OTHER: Effect on Endotracheal Tube Fixation Methods on Hemodynamic Parameters During Endotracheal Suction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cerebral and Peripheral Electrical Stimulation on Isometric Quadriceps Strength
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DEVICE: Cerebral stimulation|DEVICE: Peripheral stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Bone Cancer|Chondrosarcoma|Clear Cell Sarcoma of the Kidney|Metastatic Osteosarcoma|Ovarian Sarcoma|Recurrent Adult Soft Tissue Sarcoma|Recurrent Osteosarcoma|Recurrent Uterine Sarcoma|Stage III Adult Soft Tissue Sarcoma|Stage III Uterine Sarcoma|Stage IV Adult Soft Tissue Sarcoma|Stage IV Uterine Sarcoma
Interventions: DRUG: therapeutic angiotensin-(1-7)|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conjugate And Polysaccharide Vaccines Compared With Polysaccharide Vaccine In Hiv-Infected Adults
Status: UNKNOWN
Conditions: Pneumococcal Vaccines|HIV|HIV Infections
Interventions: BIOLOGICAL: Prevenar and Pneumo23
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Betadine Bladder Irrigations vs. Standard of Care Prior to Indwelling Catheter Removal
Status: TERMINATED
Conditions: Catheter; Infection (Indwelling Catheter)|Catheter Infection|Catheter-Related Infections|Catheter Bacteraemia|Urinary Tract Infections
Interventions: DRUG: Povidone-iodine irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess Efficacy of RXC004 +/- Nivolumab in Ring Finger Protein 43 (RNF43) or R-spondin (RSPO) Aberrated, Metastatic, Microsatellite Stable, Colorectal Cancer After Progression on Standard of Care (SOC)
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: RXC004|BIOLOGICAL: Nivolumab|BIOLOGICAL: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety, Tolerability, and Effect of a Human Monoclonal Antibody (VRC01) on Markers of HIV Persistence in HIV-Infected Adults Receiving Antiretroviral Therapy (ART)
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: VRC01|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Beta3 Agonist Treatment in Chronic Pulmonary Hypertension Secondary to Heart Failure
Status: UNKNOWN
Conditions: Pulmonary Hypertension|Mirabegron|Heart Failure|Pulmonary Vascular Resistance Abnormality
Interventions: DRUG: Mirabegron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Predicting Responses to Exhausting, Prolonged, And Repeated Exercise Demands (PREPARED) for Heat
Status: NOT_YET_RECRUITING
Conditions: Hyperthermia|Fatigue; Heat
Interventions: OTHER: 30/30 work/rest cycle|OTHER: 30/20 work/rest cycle|OTHER: 40/30 work/rest cycle|OTHER: 20/12 work/rest cycle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Does Axillary Nerve and Inferior Capsule Release Add Extra Benefit in Treating Patients With Adhesive Capsulitis
Status: RECRUITING
Conditions: Adhesive Capsulitis of Shoulder
Interventions: DRUG: steroid hydrodilatation|DRUG: axillary nerve injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Functional Capacities of Healthcare Workers With and Without Covid-19
Status: COMPLETED
Conditions: Covid19|Functional Capacity
Interventions: OTHER: 6 minute walk test|OTHER: 1 minute Sit to Stand Test|OTHER: Fatigue Severity Scale|OTHER: Medical Research Council (MRC) dyspnea scale|OTHER: SF-12|OTHER: Beck Depression Inventory|OTHER: Beck Anxiety Inventory|OTHER: 5 times sit to stand test|OTHER: 6 point Likert Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Efficacy and Safety of Zhigancao Tang Granule for HFpEF of Qi-Yin Dificiency
Status: UNKNOWN
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: Zhigancao Tang granule|DRUG: Zhigancao Tang placebo granule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of 1L Polyethylene Glycol Plus Ascorbic Acid With Prepackaged Low-Residue Diet for Bowel Preparation
Status: COMPLETED
Conditions: Colonoscopy|Colon Polyp|Bowel Preparation Solutions
Interventions: PROCEDURE: 1 L PEG with ascorbic acid with prepackaged, low residue diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lactobacillus Preparation on the Incidence of Diarrhea
Status: UNKNOWN
Conditions: Diarrhea|Death|Pneumonia
Interventions: DRUG: Lactobacillus casei variety rhamnosus granules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Rectal Microbicide Acceptability, Tolerability and Adherence
Status: COMPLETED
Conditions: HIV Prevention
Interventions: BEHAVIORAL: Placebo rectal insert|BEHAVIORAL: Placebo rectal suppository|BEHAVIORAL: Placebo rectal douche
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Occlusal Splint and Counseling to Temporomandibular Disorder
Status: UNKNOWN
Conditions: Temporomandibular Disorders|Stress Psychological|Musculoskeletal Diseases
Interventions: PROCEDURE: stabilizing appliance|PROCEDURE: Non-occluding splint, counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical & Radiographic Evaluation of Neo MTA Versus White MTA in Revascularization of Non-Vital Immature Permanent Teeth
Status: UNKNOWN
Conditions: Nonvital Tooth
Interventions: BIOLOGICAL: NeoMTA nusmile|BIOLOGICAL: White MTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Non-inferiority of Pamorelin® 11,25mg SC Injected Versus Pamorelin® 11,25mg IM Injected in Patients Suffering From Advanced Prostate Cancer (PAMOJECT)
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Triptorelin (Decapeptyl®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual-task Cycling System on Cognitive Function for the Elderly
Status: UNKNOWN
Conditions: Cognitive Impairment
Interventions: DEVICE: Dual-task Group|DEVICE: Cycling Group|DEVICE: Cognitive Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Mechanisms of Helium-Neon Laser on Melanocyte Regeneration in Skin Equivalent Vitiligo Model
Status: UNKNOWN
Conditions: Vitiligo
Interventions: PROCEDURE: foreskin from healthy adults
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC