pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Single Dose, Single Administration Study of Technosphere Inhalation Powder in Diabetic Subjects With Mild or Moderate Kidney Disease Compared to Diabetic Subjects With Normal Kidney Function
Status: COMPLETED
Conditions: Mild Nephropathy|Moderate Nephropathy|Diabetes Mellitus
Interventions: DRUG: Technosphere Inhalation Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet-Rich Plasma Therapy for Shoulder Pain in Persons With Spinal Cord Injury
Status: COMPLETED
Conditions: Shoulder Pain|Rotator Cuff Tendinitis|Rotator Cuff Syndrome|Spinal Cord Injury
Interventions: BIOLOGICAL: Platelet-rich plasma (PRP) therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pulsed Electromagnetic Field and Heparin/Bupivacaine Instillations
Status: NOT_YET_RECRUITING
Conditions: Interstitial Cystitis|Chronic Interstitial Cystitis|Bladder Pain Syndrome
Interventions: DEVICE: Pulsed Electromagnetic Field (PEMF) Device|DEVICE: Sham Pulsed Electromagnetic Feild (PEMF) Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effects of Itraconazole and Rifampin on the Pharmacokinetics of ASC40 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ASC40|DRUG: Itraconazole|DRUG: rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resilience in East Asian Immigrants for Advance Care Planning Discussions
Status: NOT_YET_RECRUITING
Conditions: Neoplasms|Advance Care Planning
Interventions: BEHAVIORAL: Culturally Tailored Digital Resilience-Building
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Interleukin-2 Gargle in the Treatment of Oral Mucosa Lesion in Pemphigus Vulgaris
Status: UNKNOWN
Conditions: Pemphigus Vulgaris
Interventions: DRUG: recombinant human interleukin-2 (rhIL-2)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Booster Vaccination Against COVID-19
Status: COMPLETED
Conditions: COVID-19|Sars-CoV-2 Infection
Interventions: BIOLOGICAL: CoronaVac|BIOLOGICAL: Turkovac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Pentoxiphylline on Left Ventricular (LV) Systolic Function Indices and Circulating Biomarkers in Patients With Chronic Congestive Heart Failure (CHF)
Status: WITHDRAWN
Conditions: Congestive Heart Failure
Interventions: DRUG: Placebo|DRUG: Pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Medical Therapy for High-risk Intracranial or Extracranial Atherosclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Stroke|Transient Ischemic Attack
Interventions: DRUG: Intensive antiplatelet|DRUG: Standard antiplatelet|DRUG: Immediate high-intensity statin|DRUG: Delayed high-intensity statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Rising Single Dose Study of the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics of MK-8892 (MK-8892-001)
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: MK-8892|DRUG: Placebo for MK-8892
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Person-Centered Versus Measurement-Based Care in Mental Health
Status: COMPLETED
Conditions: Schizophrenia|Bipolar Disorder|Major Depression
Interventions: BEHAVIORAL: Person-Centered Care|BEHAVIORAL: Measurement-Based Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Zinc Finger Nuclease CCR5-modified Hematopoietic Stem/Progenitor Cells in HIV-1 Infected Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV
Interventions: GENETIC: SB-728mR-HSPC Infusion 3 days following busulfan conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility And Safety Of Transjugular Intrahepatic Portosystemic Shunt (TIPS) Creation Using A Radiofrequency Guidewire
Status: COMPLETED
Conditions: Portal Hypertension
Interventions: DEVICE: Radiofrequency wire (Powerwire)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Improving Visual Perception and Visuo-motor Learning With Neurofeedback of Brain Network Interaction.
Status: RECRUITING
Conditions: Healthy
Interventions: BEHAVIORAL: Auditory neurofeedback|BEHAVIORAL: Tactile neurofeedback|BEHAVIORAL: Auditory and tactile neurofeedback|BEHAVIORAL: Neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of A/H1N1-SOIV (Swine Flu) Vaccine With and Without Adjuvant in Non-Elderly and Elderly Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: MF59-eH1N1_f
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Village-based vs Clinic-based ART Care - a Cluster Randomized Controlled Trial in Lesotho
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: OTHER: Standard of Care|OTHER: Village-based ART refill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children
Status: RECRUITING
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: AZM Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Total Balanced Volume Replacement Regimen in Elderly Cardiac Surgery Patients
Status: COMPLETED
Conditions: Elderly|Cardiac Surgery
Interventions: DRUG: Balanced HES 130/0.42|DRUG: Balanced HES 130/0.42|DRUG: 6% HES 130/0.4 prepared in saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bergonie Institut Profiling : Fighting Cancer by Matching Molecular Alterations and Drugs in Early Phase Trials
Status: RECRUITING
Conditions: Solid Tumor|Hematological Malignancy
Interventions: PROCEDURE: Newly obtained biopsy and Blood samples collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study on the Mechanism of Prevotella Copri Promoting the Occurrence and Development of Atherosclerosis
Status: ENROLLING_BY_INVITATION
Conditions: Atherosclerosis
Interventions: BEHAVIORAL: KAP Popular Science Research|BEHAVIORAL: No KAP Popular Science Research
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Bifidobacterium Breve Bif195 for Small Intestinal Crohn's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Crohn Disease
Interventions: DIETARY_SUPPLEMENT: Bif195 capsules|DIETARY_SUPPLEMENT: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of TAK-935 as an Adjunctive Therapy in Adult Participants With Complex Regional Pain Syndrome (CRPS)
Status: COMPLETED
Conditions: Complex Regional Pain Syndrome
Interventions: DRUG: Soticlestat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Two Novel Nasal Strip Prototypes on Nasal Patency
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DEVICE: Marketed nasal strip|DEVICE: NexGen AB 2R11|DEVICE: NexGen JB Organic PET/PE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PENG Block vs. ESP Block for Pediatric Hip Surgery
Status: COMPLETED
Conditions: Hip Dysplasia|Hip Injuries|Hip Fractures|Hip Disease
Interventions: DRUG: Pericapsular nerve group block using 0.2% ropivacaine|DRUG: Erector Spinae Plane Block using 0.2% ropivacaine|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ctDNA-guided Surveillance for Stage III CRC, a Randomized Intervention Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer|Colo-rectal Cancer|ctDNA|Gastro-Intestinal Disorder|Colorectal Neoplasms|Gastrointestinal Cancer|Gastrointestinal Neoplasms|Digestive System Disease|Digestive System Neoplasm|Colonic Diseases|Colonic Neoplasms|Colonic Cancer|Rectal Diseases|Rectal Neoplasms|Rectal Cancer
Interventions: DIAGNOSTIC_TEST: ctDNA-analysis|OTHER: Intensified Follow-up Schedule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Iron Status and Human Metabolism
Status: COMPLETED
Conditions: Iron Deficiency
Interventions: DRUG: Ferric carboxymaltose|DRUG: Sodium chloride (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy Safety Study of Flu Vaccine in Immunodepression Patients
Status: COMPLETED
Conditions: Inflammatory Bowel Disease (IBD)
Interventions: DRUG: Vaccine|BIOLOGICAL: Vaccine anti-H1N1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of Two Formulations of AKB-6548 and the Food Effect of a New Tablet in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AKB-6548 tablet, reference formulation given in the fasted state|DRUG: AKB-6548 tablet, test formulation given in the fasted state.|DRUG: AKB-6548 tablet, test formulation given in the fed state
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bright Light Exposure in Critical Ill Patients
Status: RECRUITING
Conditions: Myocardial Ischemia|Critical Illness|Endothelial Dysfunction
Interventions: DEVICE: Day Light|DEVICE: Placebo light|DEVICE: ICU Intense Light|DEVICE: ICU Placebo light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prospective, Randomized, Multicenter Study to Assess the Safety and Effectiveness of the Orsiro Sirolimus-eluting Stent
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Abbott Laboratories Xience|DEVICE: Biotronik Orsiro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Precision Nudging Drives Wellness Visit Attendance at Scale
Status: COMPLETED
Conditions: Women's Health|Annual Visit|Well Visit|Health Behavior|Prevention
Interventions: OTHER: Precision nudging|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study on Reduced Antibiotic Treatment vs Broad Spectrum Betalactam in Patients With Bacteremia by Enterobacteriaceae
Status: COMPLETED
Conditions: Enterobacteriaceae Infections
Interventions: DRUG: Antipseudomonal beta-lactam antibiotic|DRUG: De-escalation(short-spectrum antibiotic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Tretinoin and Arsenic Trioxide for Patients With Newly Diagnosed Acute Promyelocytic Leukemia Followed by Risk-Adapted Postremission Therapy
Status: COMPLETED
Conditions: Acute Promyelocytic Leukemia
Interventions: DRUG: Tretinoin and Arsenic Trioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Dose or High-Dose Lenalidomide in Treating Younger Patients With Recurrent, Refractory, or Progressive Pilocytic Astrocytoma or Optic Pathway Glioma
Status: COMPLETED
Conditions: Neurofibromatosis Type 1|Recurrent Childhood Pilocytic Astrocytoma|Recurrent Childhood Visual Pathway Glioma
Interventions: DRUG: Lenalidomide|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of SMART [Spastic Muscle Palpation by Anatomic Landscape for BoNT-A (Botulinumtoxin-A) Injection to Reduce Muscle Tone] BoNT-A Therapy With Dysport® in Patients With Post-stroke Chronic Upper Limb Spasticity (ULS) in Real-life Setting.
Status: RECRUITING
Conditions: Post-Stroke Chronic Upper Limb Spasticity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase II Study of Durvalumab Treatment - Substudy A: In Patients Who Discontinued Prior Checkpoint Therapy Due to Immune Related Toxicity - Substudy B: For Continued Treatment (+/- Tremelimumab) of Patients Previously Enrolled to Completed CCTG Studies
Status: RECRUITING
Conditions: Cancer
Interventions: DRUG: Durvalumab|DRUG: Prednisone|DRUG: Prednisone|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Relapsed or Refractory Epstein-Barr Virus Positive T-cell Lymphoma With hNeo-T
Status: RECRUITING
Conditions: T-cell Lymphoma
Interventions: BIOLOGICAL: hNeo-T|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kadcyla And Neratinib for Interception of HER2+ Breast Cancer With Molecular Residual Disease
Status: RECRUITING
Conditions: Breast Cancer|HER2-positive Breast Cancer
Interventions: DRUG: Neratinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Örebro Multicenter Study on Operative Treatment of Cervical Radiculopathy
Status: RECRUITING
Conditions: Cervical Radiculopathy|Cervical Root Compression
Interventions: PROCEDURE: ACDF|PROCEDURE: PF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exenatide (Byetta ®) Regulation of Intestinal and Hepatic Lipoprotein Particle Production in Humans
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: exenatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An International Randomized Study to Compare SPIES Versus WLI
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DEVICE: SPIES+WLI assisted TURB|DEVICE: WLI assisted TURB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: SUPPLEMENTATION WITH BETA GLUCAN AND ADAPTATIVE RESPONSE.
Status: NOT_YET_RECRUITING
Conditions: Clinical Course
Interventions: DIETARY_SUPPLEMENT: BioNutri AR-1,
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Peptide Vaccine in Treating Patients With Advanced Pancreatic Cancer or Colorectal Cancer
Status: RECRUITING
Conditions: Metastatic Colorectal Adenocarcinoma|Metastatic Pancreatic Ductal Adenocarcinoma|Stage IV Colorectal Cancer AJCC v7|Stage IV Pancreatic Cancer AJCC v6 and v7|Stage IVA Colorectal Cancer AJCC v7|Stage IVB Colorectal Cancer AJCC v7
Interventions: DRUG: Imiquimod|BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Sotigalimab|BIOLOGICAL: Synthetic Tumor-Associated Peptide Vaccine Therapy|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CCTA Coronary Hemodynamics, Systemic Inflammation and Vulnerable Plaques (COHESIVE)
Status: UNKNOWN
Conditions: Coronary Artery Disease|Systemic Inflammatory Response|Chronic Coronary Syndrome|Atherosclerosis
Interventions: DIAGNOSTIC_TEST: Cardiac imaging tests|DIAGNOSTIC_TEST: Venous blood sample collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rifaximin for Preventing Relapse of Clostridium Associated Diarrhoea
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: DRUG: Rifaximin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Scientific Evaluation of Peer Education and STD Treatment to Reduce the Spread of HIV in Zimbabwe
Status: COMPLETED
Conditions: HIV Infections
Interventions: BEHAVIORAL: Peer education among commercial sex workers and clients|BEHAVIORAL: Condom distribution and promotion|PROCEDURE: Syndromic treatment of sexually transmitted infections|PROCEDURE: Systemic counselling for STI patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study of the Combination of SHR8554 Injection and SHR0410 Injection for the Treatment of Pain After Abdominal Surgery.
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: SHR8554 Injection and SHR0410 Injection|DRUG: SHR8554 Injection and SHR0410 Injection|DRUG: SHR8554 Injection and Placebo for SHR0410 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intermittent Hypoxia Elicits Prolonged Restoration of Motor Function in Human SCI
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: OTHER: Acute intermittent hypoxia|OTHER: Room air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Natural Resources for Reducing Stress
Status: ACTIVE_NOT_RECRUITING
Conditions: Distress, Emotional|COVID-19
Interventions: COMBINATION_PRODUCT: Balneotherapy plus complex|COMBINATION_PRODUCT: Combined nature resources treatment|OTHER: Nature therapy procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Does Disinfection of the Subcutaneous Tissue Reduce Contamination of the Operating Field With P. Acnes?
Status: UNKNOWN
Conditions: Surgical Incision
Interventions: PROCEDURE: subcutaneous tissue disinfection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating DVS-233 SR And Venlafaxine ER In Adult Outpatients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: DVS-233 SR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Extension Safety Study of PROCRIT in Patients With Anemia of Chronic Disease Due to Rheumatoid Arthritis
Status: WITHDRAWN
Conditions: Anemia|Rheumatoid Arthritis
Interventions: DRUG: Epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasopharyngeal Versus Laryngeal Mask Airway in Anaesthesia for Bilateral Blepharoplasty
Status: COMPLETED
Conditions: Injury Throat
Interventions: DEVICE: Nasopharyngeal airway or laryngeal mask airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Medroxyprogesterone Acetate With or Without Entinostat Before Surgery in Treating Patients With Endometrioid Endometrial Cancer
Status: COMPLETED
Conditions: FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma|FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma|FIGO Grade 3 Endometrial Endometrioid Adenocarcinoma
Interventions: DRUG: Entinostat|PROCEDURE: Hysterectomy|OTHER: Laboratory Biomarker Analysis|DRUG: Medroxyprogesterone Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Octreotide LAR as Maintenance Treatment for Patients With NEC
Status: UNKNOWN
Conditions: Gastro-entero-pancreatic Carcinoma|Esophageal Neuroendocrine Carcinoma
Interventions: DRUG: Octreotide lar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AMG 706 and Octreotide in Treating Patients With Low-Grade Neuroendocrine Tumors
Status: COMPLETED
Conditions: Gastrointestinal Carcinoid Tumor|Islet Cell Tumor|Neoplastic Syndrome
Interventions: DRUG: AMG 706|DRUG: octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decompressive Craniectomy in Patients With Cerebellar Infarction
Status: COMPLETED
Conditions: Cerebellar Stroke
Interventions: PROCEDURE: suboccipital decompressive craniectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Study of Safety and Tolerability of DCR HBVS
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: DCR-HBVS|DRUG: Placebo for DCR-HBVS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic, Safety and Immunogenicity Phase I Study of HLX04 Versus Avastin® in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Male Subjects
Interventions: DRUG: HLX04|DRUG: US-Avastin®|DRUG: EU-Avastin®|DRUG: CN-Avastin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IV Study of the Safety and Efficacy of Everolimus in Adult Patients With Progressive pNET in China
Status: COMPLETED
Conditions: Pancreatic Neuroendocrine Tumors
Interventions: DRUG: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Humans to Assess the Relative Bioavailability of One Fixed-dose Combination Tablet Empagliflozin/Metformin Versus Jardiance® Tablet and Glifage® Tablet Administered Together
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: FDC 12.5mg empagliflozin/850mg metformin|DRUG: Empagliflozin|DRUG: Glifage®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib and Vorinostat in Treating Patients With High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: bortezomib|DRUG: vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Celecoxib (Celebrex 200 mg) Combined With Joins in the Treatment of Degenerative Knee Osteoarthritis: a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DRUG: Celebrex with Joins or not
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Infectivity and Illness of Norwalk GI.1 Virus Lot 001-09NV in the Human Challenge Model
Status: COMPLETED
Conditions: Norovirus Infection
Interventions: BIOLOGICAL: Norwalk GI.1 Virus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of TUSP Versus TURP for Treatment of Benign Prostatic Hyperplasia in a Small Prostate Volume
Status: UNKNOWN
Conditions: Benign Prostatic Hyperplasia
Interventions: PROCEDURE: TUSP|PROCEDURE: TURP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Positional Release and Manual Pressure Technique in Chronic Low Back Pain
Status: RECRUITING
Conditions: Chronic Low-back Pain
Interventions: DEVICE: Positional Release Technique|DEVICE: Manual Pressure Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of SEP Exercises Versus SSMP With Tendon Loading & Resistance Exercise in Shoulder Pain.
Status: COMPLETED
Conditions: Subacromial Pain Syndrome
Interventions: BEHAVIORAL: Single exercise into pain (SEP) program|BEHAVIORAL: Shoulder Symptom Modification Procedure (SSMP)|BEHAVIORAL: Functional Rehabilitation Program|BEHAVIORAL: EPTL|BEHAVIORAL: HSR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S9716: Combination Chemotherapy in Treating Patients With Merkel Cell Cancer
Status: COMPLETED
Conditions: Neuroendocrine Carcinoma of the Skin
Interventions: DRUG: CMF regimen|DRUG: cyclophosphamide|DRUG: fluorouracil|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-MFBG Imaging for Evaluation of Neuroendocrine Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Tumors
Interventions: RADIATION: 18F-MFBG (meta-fluoro benzylguanidine)|DEVICE: Positron emission tomography (PET) imaging|OTHER: Blood draws
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Group Cognitive Behavioral Therapy for Psychological Sub-health
Status: RECRUITING
Conditions: Mental Suffering
Interventions: BEHAVIORAL: Group Cognitive Behavioral Therapy (GCBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Maytenus Ilicifolia in the Treatment of Dyspepsia
Status: TERMINATED
Conditions: Dyspepsia
Interventions: DRUG: Maytenus ilicifolia leaves infusion|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of ABI-007(Albumin-bound Paclitaxel) Plus Gemcitabine Versus Gemcitabine in Metastatic Adenocarcinoma of the Pancreas
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Albumin-bound paclitaxel (ABI-007)|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Smart Hearing Aid on Improving Psychosocial Well-being in Elderly
Status: COMPLETED
Conditions: Technology
Interventions: DEVICE: Experimental group intervention|DEVICE: Wait-list control group intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate Multiple Doses in Patients With Nasal Polyposis
Status: COMPLETED
Conditions: Nasal Polyposis
Interventions: DRUG: AK001 low dose|DRUG: AK001 high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Dose Study With BPL-003 in Healthy Subjects
Status: COMPLETED
Conditions: Pharmacokinetics in Healthy Adults
Interventions: DRUG: BPL-003|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health and Justice: A Continuum of Care for HIV and SU for Justice-Involved Young Adults (PHASE 2)
Status: COMPLETED
Conditions: HIV/AIDS|HIV Infections|Substance Use|Substance Abuse|Substance Use Disorders|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: Link2CARE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Optiflow vs. Convential Anesthesia During Pediatric Laryngeal Papilloma Removal
Status: WITHDRAWN
Conditions: Laryngeal Papilloma, Recurrent
Interventions: PROCEDURE: Transnasal humidified high-flow oxygen delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ClarVista HARMONI Toric Trial With Intraoperative Exchange
Status: COMPLETED
Conditions: Cataract|Corneal Astigmatism|Aphakia
Interventions: DEVICE: HARMONI® Modular Intraocular Lens System|PROCEDURE: Intraoperative optic exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Obinutuzumab in Combination With Chemotherapy in Participants With CD20+ B-Cell Follicular Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Bendamustine|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Fludarabine|DRUG: Obinutuzumab|DRUG: Prednisone|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)
Status: RECRUITING
Conditions: Prostate Cancer|Metastatic Castration-resistant Prostate Cancer|Castration Resistant Prostatic Cancer
Interventions: BIOLOGICAL: JANX007
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigational Study For the Treatment of Localized (T1c/T2a) Prostate Cancer With High Intensity Focused Ultrasound (HIFU) Using the Sonablate 500 (SB-500) System in Canada
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: DEVICE: Sonablate 500(SB-500)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dual Tasks on ADL in Stroke
Status: COMPLETED
Conditions: Stroke|Dual Task|Activity of Daily Living
Interventions: OTHER: Dual Task MC|OTHER: Dual Task MM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Local Anesthetic for Plateau Fractures
Status: NOT_YET_RECRUITING
Conditions: Tibial Plateau Fractures
Interventions: DRUG: Bupivacaine injection|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of The Mindfulness-based Childbirth and Parenting Program
Status: COMPLETED
Conditions: Pregnancy Related
Interventions: OTHER: Mindfulness-based Childbirth and Parenting Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical and Radiographic Evaluation of Alkasite Restorative Material Versus Glass Ionomer Cement
Status: NOT_YET_RECRUITING
Conditions: Tooth Decay
Interventions: OTHER: ALKASITE RESTORATIVE MATERIAL|OTHER: Glass Ionomer Cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interhospital Variability in Programmes to Prevent Axillary Lymphadenectomy Sequels in Breast Cancer Patients.
Status: COMPLETED
Conditions: Breast Cancer Lymphedema|Shoulder Injury
Interventions: OTHER: Fulfillment of a preventive programme|OTHER: No fulfillment of a preventive programme
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Study of Imatinib Mesylate to Treat Philadelphia-Positive Acute Lymphocytic Leukemia
Status: COMPLETED
Conditions: Philadelphia Chromosome Positive Acute Lymphocytic Leukemia
Interventions: DRUG: Imatinib Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Adding Bevacizumab to First Line Chemotherapy in Lung Cancer Patients With Stable Disease
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer Metastatic
Interventions: DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ianalumab Versus Placebo in Addition to First-line Corticosteroids in Primary Immune Thrombocytopenia (ITP)
Status: RECRUITING
Conditions: Primary Immune Thrombocytopenia (ITP)
Interventions: BIOLOGICAL: Ianalumab|DRUG: Placebo|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of a Mediterranean Diet in Patients With Endometriosis: a Feasibility Trial
Status: ENROLLING_BY_INVITATION
Conditions: Endometriosis
Interventions: BEHAVIORAL: Diet Modification to Adopt Mediterranean Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neuropsychological and Brain Medical Imaging Study in Patients With Brain Damage
Status: UNKNOWN
Conditions: Cerebrovascular Disorders|Brain Lesions|Degenerative Diseases|Developmental Pathology
Interventions: BEHAVIORAL: Neuropsychological testing|OTHER: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Determine the Efficacy of Topically Applied MTC896 Gel in Subjects With Acne Vulgaris
Status: UNKNOWN
Conditions: Acne Vulgaris
Interventions: DRUG: 0.375% (w/w) MTC896 Gel|DRUG: 0.75% (w/w) MTC896 Gel|DRUG: 1.5% (w/w) MTC896 Gel|DRUG: Vehicle Control Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Histopathologic and Lymphocyte Subpopulations Evaluation of the Upper Gastrointestinal Tract of Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: BEHAVIORAL: General variables|BEHAVIORAL: Clinical activity|PROCEDURE: Laboratory data|PROCEDURE: Endoscopic and histology data
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tension Band Versus Locking Plate Fixation for the Treatment of Patella Fractures
Status: RECRUITING
Conditions: Patella Fracture|Surgery|Orthopedic Disorder
Interventions: PROCEDURE: Tension band fixation|PROCEDURE: Plate fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of Multi-parameter Non-Invasive Glucose Sensors for for Blood Glucose Measurement
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DEVICE: Non-invasive glucose meter|DEVICE: EKF analyzer|DEVICE: Accu-Chek Guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Efficacy and Safety Study of Favipiravir for Treatment of Uncomplicated Influenza in Adults - T705US316
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: favipiravir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FGF19 in Obstructive Cholestasis: "Unveil the Signal"
Status: RECRUITING
Conditions: Cholestasis|Icterus|Cholangiocarcinoma|Pancreatic Neoplasms|Liver Metastasis Colon Cancer
Interventions: OTHER: Biospecimen sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Investigating the Pharmacokinetics, Pharmacodynamics and Safety of FE200486
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Degarelix|DRUG: Degarelix|DRUG: Degarelix|DRUG: Degarelix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of 177Lu Human Monoclonal Antibody 5B1 (MVT-1075) in Combination With a Blocking Dose of MVT-5873 as Radioimmunotherapy
Status: TERMINATED
Conditions: Pancreatic Carcinoma|Tumors That Express CA 19-9
Interventions: DRUG: MVT-1075|DRUG: MVT-5873
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Plasma Exchange Alone or in Combination With Ruxolitinib in COVID-19 Associated CRS
Status: COMPLETED
Conditions: Cytokine Release Syndrome|COVID19
Interventions: PROCEDURE: Therapeutic Plasma Exchange|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TAK-676 With Pembrolizumab After Radiation Therapy to Treat a Number of Cancers
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Triple Negative Breast Neoplasms|Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: Pembrolizumab|DRUG: TAK-676|RADIATION: Image-guided radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Assess the Safety and Immunogenicity of New Malaria Vaccine Candidates ChAd63 Pfs25-IMX313 and MVA Pfs25-IMX313
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: ChAd63 Pfs25-IMX313|BIOLOGICAL: MVA Pfs25-IMX313
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 9-valent CRM 197 Pneumococcal
Status: COMPLETED
Conditions: Pneumococcal Infection
Interventions: DRUG: Placebo|BIOLOGICAL: PNU-IMUNE®23|BIOLOGICAL: Nine-valent pneumococcal conjugate (PNCRM9)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of a fNIRS-based Personalized Multi-domain Intervention on Cognitive in Elderly Population With High Risk of Stroke
Status: NOT_YET_RECRUITING
Conditions: Cognitive Impairment|Stroke|Dementia
Interventions: BEHAVIORAL: Personalized multidomain intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Over-arousal as a Mechanism Between Alcohol and Intimate Partner Violence
Status: COMPLETED
Conditions: Domestic Violence|Alcohol Consumption
Interventions: DRUG: Alcohol beverage|DRUG: Placebo beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: African American Cancer Clinical Trial Decisions: Testing Tailored Messages
Status: COMPLETED
Conditions: Myeloma|Lymphoma|Leukemia
Interventions: BEHAVIORAL: EMR Tailoring|BEHAVIORAL: Survey Tailoring|BEHAVIORAL: Physician Involvement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Whole Body Electromyostimulation and Nutritional Therapy for Patients With Esophageal and Bronchial Carcinoma
Status: UNKNOWN
Conditions: Cancer of Esophagus|Cancer, Lung
Interventions: PROCEDURE: whole body electromyostimulation exercise|PROCEDURE: protein-rich nutrition therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial Study of an Exercise Program for Youth With Persistent Symptoms After Concussion
Status: TERMINATED
Conditions: Concussion|Sport-Related Concussion|Mild Traumatic Brain Injury
Interventions: OTHER: Active Rehabilitation|OTHER: Comprehensive Education Intervention (Standard Care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Twin SUBLIVAC® Grasses Clinical Efficacy Study
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal|Conjunctivitis, Allergic
Interventions: DRUG: SUBLIVAC® Grasses/Placebo treatment|DRUG: SUBLIVAC® Grasses treatment|DRUG: Placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recovery Strategies Based on Mindfulness and Physical Exercise on Levels of Stress and Inmunoglobulin A
Status: COMPLETED
Conditions: Mental Health Wellness
Interventions: BEHAVIORAL: Mindfulness-based intervention|BEHAVIORAL: Physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Optical Molecular Imaging for Percutaneous Biopsy of Hepatocellular Carcinoma Using Indocyanine Green
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: ICG|DEVICE: Optical molecular imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Clinical Trial to Investigate the Pharmacokinetics and Safety/Tolerability of CKD-387 Under Fed Condition
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: CKD-387|DRUG: D484
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptance and Commitment Therapy With Vestibular Rehabilitation for Chronic Dizziness
Status: COMPLETED
Conditions: Chronic Dizziness
Interventions: BEHAVIORAL: ACT with VR|BEHAVIORAL: self-treatment VR|OTHER: clinical management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IN.PACT BTK Randomized Study to Assess Safety and Efficacy of IN.PACT 014 vs. PTA
Status: COMPLETED
Conditions: Critical Limb Ischemia|Peripheral Arterial Disease
Interventions: DEVICE: DCB|DEVICE: PTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Lifestyle Intervention Targeting Enhanced Health and Function for Persons With Chronic SCI in Caregiver/Care-Receiver Relationships: Effects of Caregiver Co-Treatment
Status: COMPLETED
Conditions: Spinal Cord Injury|Cardiovascular Diseases|Obesity
Interventions: BEHAVIORAL: Spinal Cord Injury (SCI)|BEHAVIORAL: Caregiver Intervention(CCC)|BEHAVIORAL: Caregiver Control (CC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Rapid and Slow Glucose Fall on the Subsequent Glucose Production in People With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes|Blood Glucose, Low|Glucose Metabolism Disorders
Interventions: OTHER: Rapid lowering of plasma glucose|OTHER: Slow lowering of plasma glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Predictive Model for the Occurrence of Cerebral Vasospasm Complicating Subarachnoid Haemorrhage by Combined Analysis of the Kinetics of a Panel of Biomarkers.
Status: RECRUITING
Conditions: Cerebral Vasospasm
Interventions: OTHER: Samples collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC