pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Tezepelumab on Airway Structure and Function in Patients With Uncontrolled Moderate-to-severe Asthma
Status: RECRUITING
Conditions: Asthma
Interventions: BIOLOGICAL: Tezepelumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Learning Optical Coherence Tomography (OCT) and OCT Angiography (OCTA) in NVC
Status: COMPLETED
Conditions: Macular Degeneration Choroidal Neovascularization
Interventions: DIAGNOSTIC_TEST: Diagnostic test: using artificial intelligence to evaluate the changes OCT and OCTA parameter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Collect Imaging Data for the Validation of the Intelligent Ultrasound's ScanNav Anatomy Peripheral Nerve Block (PNB) - US v1.0
Status: COMPLETED
Conditions: Ultrasound Imaging of Anatomical Structures
Interventions: DEVICE: Ultrasound scans
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quetiapine in Co-Morbid Depressive and Anxiety Disorders
Status: COMPLETED
Conditions: Major Depressive Disorder|Dysthymic Disorder|Anxiety Disorders|Generalized Anxiety Disorder|Social Anxiety Disorder|Panic Disorder|Post-traumatic Stress Disorder
Interventions: DRUG: Quetiapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Treatment With Abatacept to Promote Remission During Peanut Oral Immunotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Peanut Allergy
Interventions: DRUG: Abatacept|DRUG: Placebo|OTHER: Peanut oral immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Group and Mobile Care for Gestational Diabetes
Status: COMPLETED
Conditions: Gestational Diabetes
Interventions: OTHER: GlucoseMama application with blood sugar monitoring and carb monitoring.|OTHER: Group prenatal care for GDM.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: IM Olanzapine Versus Haloperidol or Midazolam
Status: TERMINATED
Conditions: Acute Agitation, Behavioural Emergency
Interventions: DRUG: Olanzapine|DRUG: Haloperidol|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacist-led Transitions of Care in the Outpatient Oncology Infusion Center for Patients With Solid Tumor
Status: COMPLETED
Conditions: Malignant Solid Neoplasm
Interventions: OTHER: Medical Chart Review|OTHER: Educational Intervention|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: SARS-CoV-2 and Acetylsalicylic Acid (SARA)
Status: COMPLETED
Conditions: SARS-CoV2 Infection|Covid19
Interventions: DRUG: Low-dose acetylsalicylic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neuropsychological Functioning in Children With Attention-Deficit/Hyperactivity Disorder.
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Atomoxetine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BPPV With CRP: Single Versus Multiple Cycles
Status: UNKNOWN
Conditions: Benign Paroxysmal Positional Vertigo (BPPV)
Interventions: PROCEDURE: Canalith repositioning procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Early Passive and Active Mobilization Protocols in Flexor Tendon Repair Rehabilitation of the Hand
Status: COMPLETED
Conditions: Tendon Injuries
Interventions: PROCEDURE: early active mobilization|PROCEDURE: early passive mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REsynchronization Comparison In LBBB and Normal or Mildly Reduced VENTricular Function With CRT (REINVENT-CRT)
Status: COMPLETED
Conditions: Left Ventricular Ejection Fraction|Heart Failure (HF)|Left Bundle-Branch Block
Interventions: DEVICE: LB-CRT|DEVICE: BIV-CRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: A New Approach in Laser Surgery Using the Regenerative Solution in Children Diagnosed With Vascular Pathology
Status: COMPLETED
Conditions: Vascular Diseases|Vascular Malformation|Capillary Malformation-Arteriovenous Malformation|Port-Wine Stain|Sturge-Weber Syndrome|Vascular Tumor
Interventions: DRUG: Haemoblock|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics of Empagliflozin (BI 10773) in Patients With Impaired Liver Function
Status: COMPLETED
Conditions: Hepatic Insufficiency|Healthy
Interventions: DRUG: BI 10773
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 177Lu-DTPA-Omburtamab Radioimmunotherapy for Recurrent or Refractory Medulloblastoma
Status: TERMINATED
Conditions: Medulloblastoma, Childhood
Interventions: DRUG: 177Lu-DTPA-omburtamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound for Prediction of Empty Stomach in Infants
Status: COMPLETED
Conditions: Children, Only|Pulmonary Aspiration|Anesthesia|Fasting
Interventions: OTHER: Group 1 (Patients who recorded as Grade 0)|OTHER: Group 2 ( Patients who recorded as Grade 1)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pediatric ADVAIR DISKUS Versus Oral Montelukast Chewable Tablets
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: montelukast (5mg QD)|DRUG: Salmeterol/Fluticasone propionate Inhalation Powder (50/100mcg BID)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Moderate vs Deep Neuromuscular Block on Biotrauma During Laparoscopy
Status: COMPLETED
Conditions: Pneumoperitoneum
Interventions: DRUG: Deep neuromuscular block|DRUG: Moderate neuromuscular block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Methylene Blue Versus Vasopressin Analogue for Treatment of Septic Shock in Preterm Neonate
Status: UNKNOWN
Conditions: Neonatal Sepsis|Refractory Shock
Interventions: DRUG: Methylene Blue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic oHCM (SEQUOIA-HCM)
Status: COMPLETED
Conditions: Obstructive Hypertrophic Cardiomyopathy (oHCM)
Interventions: DRUG: CK-3773274 (5 mg, 10 mg, 15 mg and 20 mg)|DRUG: Placebo to match CK-3773274
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-term Safety Study for Long-acting Injectable Risperidone in Schizophrenia or Schizoaffective Disorder Patients.
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Results of Arthroscopic Suturing of the Medial Meniscus Using the Fast Fix and FiberStitch Systems
Status: UNKNOWN
Conditions: Meniscus; Detachment, Current Injury|Detachment|Medial Mensical Tear|Medial Meniscus Knee Injury
Interventions: PROCEDURE: Medial Meniscus Arthroscopic Reconstruction Using the Fast Fix|PROCEDURE: Medial Meniscus Arthroscopic Reconstruction Using the Fiber Stitch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Dysport Reconstitution at 1.5 mL and 2.5 mL for the Treatment of Moderate to Severe Glabellar Lines
Status: COMPLETED
Conditions: Glabellar Lines|Wrinkles
Interventions: DEVICE: Dysport reconstituted at 1.5 mL (0.05 mL/injection)|DEVICE: Dysport reconstituted at 2.5 mL (0.08 mL/injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of NP002 in Subjects With Idiopathic Parkinson's Disease to Treat Dyskinesias Due to Levodopa Therapy
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: nicotine|OTHER: placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Synergistic Anti-tumor Effect of ChangTai Keli for Colon Cancer Patients
Status: UNKNOWN
Conditions: Colon Cancer
Interventions: DRUG: mFOLFOX6|DRUG: XELOX|DRUG: Placebo ChangTai Keli|DRUG: ChangTai Keli
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Safety of Axiom Worldwide DRX9000 Axial Decompression System for Treatment of Low Back Pain
Status: WITHDRAWN
Conditions: Low Back Pain
Interventions: DEVICE: DRX9000™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Zanubrutinib in Patients With Indolent B-cell Lymphomas
Status: RECRUITING
Conditions: Follicular Lymphoma|Marginal Zone Lymphoma|B-Cell Lymphoma
Interventions: DRUG: Zanubrutinib|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Of Resistance Training And Core Strengthening Exercises Vitamin D In Postmenopausal Women With Low Back Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Menopausal|Pain, Low Back
Interventions: DIAGNOSTIC_TEST: Resistance Training and Core Strengthening Exercises Group|DIAGNOSTIC_TEST: Resistance Training and Core Strengthening Exercises Group Plus Vitamin D Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Effect of Lansoprazole on Infants With Gastroesophageal Reflux Disease.
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Lansoprazole|DRUG: Lansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Factors Influencing the COVID-19 Vaccine Immune Response According to Age and Presence or Not of a Past History of COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: BIOLOGICAL: COVID-19 vaccine Pfizer (2 doses)|BIOLOGICAL: COVID-19 vaccine Pfizer (1 dose)|BIOLOGICAL: COVID-19 mRNA Vaccine Moderna (2 doses)|BIOLOGICAL: COVID-19 mRNA Vaccine Moderna (1 dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Prospective Evaluation of Pancreatic Function in Pancreas Transplant Recipients
Status: COMPLETED
Conditions: Transplant|Diabetes
Interventions: PROCEDURE: Oral glucose tolerance test|PROCEDURE: IV Glucose Tolerance Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Performance Of Class I Composite Restorations After Cavity Finishing By Air Abrasion Versus Diamond Stone
Status: NOT_YET_RECRUITING
Conditions: Abrasion, Dental|Class I Dental Caries
Interventions: OTHER: Bioactive Glass Air Abrasion Particles.|OTHER: Diamond Stone.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Ischemic Conditioning in Individuals With Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Ischemic conditioning group|DEVICE: Sham group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Etoposide, Carboplatin, and Bleomycin in Treating Young Patients Undergoing Surgery For Malignant Germ Cell Tumors
Status: UNKNOWN
Conditions: Brain and Central Nervous System Tumors|Childhood Germ Cell Tumor|Extragonadal Germ Cell Tumor|Ovarian Cancer
Interventions: BIOLOGICAL: bleomycin sulfate|DRUG: carboplatin|DRUG: etoposide|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Energy Technique and Static Stretching on Pain Intensity and Functional Disability in Patients With Mechanical Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: DEVICE: Muscle Enery Techniques|DEVICE: Static Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simulated Driving Study in Restless Legs Syndrome
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: XP13512|DRUG: Diphenhydramine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: New Mexico Honey Wound Treatment Research Study
Status: UNKNOWN
Conditions: Community-acquired Methicillin-resistant Staphylococcus Aureus Infection
Interventions: DRUG: New Mexico Honey|DRUG: Bactrim DS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety And Tolerability Of Escalating Intravenous Doses Of PF-05231023 In Adult Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: PF-05231023|DRUG: PF-05231023|DRUG: PF-05231023|DRUG: PF-05231023|DRUG: PF-05231023|DRUG: PF-05231023|DRUG: PF-05231023|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post Market Clinical Follow-Up Study on the Performance and Safety of Lyoplant®
Status: ENROLLING_BY_INVITATION
Conditions: Tumor, Cerebral Ventricle|Tumor, Cerebellar|Aneurysm Cerebral|Trauma, Brain
Interventions: DEVICE: Lyoplant®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: R-5780-01 In Combination With PD-1 Checkpoint Inhibitors (Checkpoint Protein on Immune Cells Called T Cells) in Patients With Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor, Adult|Solid Tumor|Melanoma|Basal Cell Cancer|Squamous Cell Cancer|Adenoma
Interventions: DRUG: R-5780
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: sargramostim|DRUG: busulfan|DRUG: etoposide|DRUG: fludarabine phosphate|DRUG: prednisone|DRUG: tacrolimus|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: umbilical cord blood transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compression Garments in the Community With POTS
Status: RECRUITING
Conditions: Postural Orthostatic Tachycardia Syndrome
Interventions: OTHER: Waist-High Compression Tights|OTHER: Abdominal Compression Garments|DRUG: Medications that modulate heart rate and blood pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Of CP-690,550 On The Pharmacokinetics Of Metformin In Healthy Volunteers
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Metformin/CP-690,550
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Iron Supplementation on Pediatric Vaccine Response
Status: COMPLETED
Conditions: Iron-deficiency|Iron Deficiency Anemia|Vaccination|Pediatric ALL
Interventions: DIETARY_SUPPLEMENT: Iron syrup|DIETARY_SUPPLEMENT: Multivitamin syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Total Versus Robotic Assisted Unicompartmental Knee Replacement
Status: NOT_YET_RECRUITING
Conditions: Osteo Arthritis Knee|Arthritis Knee|Arthropathy of Knee
Interventions: DEVICE: MAKO™ Partial Knee Arthroplasty|DEVICE: Triathlon (Stryker) Total Knee Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liposome Entrapped Paclitaxel Easy to Use (LEP-ETU) in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Neoplasm
Interventions: DRUG: Liposome Entrapped Paclitaxel Easy to Use
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study About the Role of COX-2 Inhibitor in Liver Cirrhosis With Biliary Atresia
Status: COMPLETED
Conditions: Biliary Atresia, Kasai Portoenterostomy Status
Interventions: DRUG: Meloxicam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acetylcysteine, Theophylline, and a Combination of Both in the Prophylaxis of Contrast-Induced Nephropathy
Status: COMPLETED
Conditions: Contrast Induced Nephropathy|Kidney Diseases|Renal Failure|Adverse Effects
Interventions: DRUG: Acetylcysteine|DRUG: Theophylline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Minimally Invasive Techniques for Treating Large Proximal Ureteral Stones
Status: COMPLETED
Conditions: Endourology
Interventions: PROCEDURE: transperitoneal laparoscopic ureterolithotomy (T-LUL)/ retrograde flexible ureteroscopy (R-URS) /Antegrade mini-percutaneous flexible ureteroscopy (A-URS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Angiogenesis and Blood Perfusion Effect of HGF Gene Therapy in PAD Patients
Status: RECRUITING
Conditions: Peripheral Artery Disease
Interventions: DRUG: NL003|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Dendritic Cell Vaccine in Patients With Soft Tissue Sarcoma
Status: UNKNOWN
Conditions: Sarcoma|Neoplasms, Connective and Soft Tissue
Interventions: BIOLOGICAL: Autologous dendritic cell vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of an Abdominal Hypopressive Technique Program on Pelvic Floor Muscles and Urinary Incontinence in Women
Status: COMPLETED
Conditions: Mild Pelvic Floor Dysfunction
Interventions: OTHER: Abdominal hypopressive technique
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Gammaglobulin for Sickle Cell Pain Crises
Status: RECRUITING
Conditions: Sickle Cell Disease|Pain
Interventions: DRUG: Immune Globulin Intravenous|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of an Online Program to Help Parents Talk With Their Tween Children About Health, Gender, Body-Image, and Relationships
Status: RECRUITING
Conditions: Parenting|Parent-Child Relations|Communication
Interventions: BEHAVIORAL: Media Aware Parent - Tween|BEHAVIORAL: Active Control Resource
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Laying-on-of-hands for Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease|Pain Crisis Recurrent|Anemia|Infection|Death
Interventions: BEHAVIORAL: laying-on-of-hands
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Stress Reduction Program in Patients With Malignant Brain Tumors and Their Family Caregivers
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Psychosocial Effects of Cancer and Its Treatment
Interventions: BEHAVIORAL: exercise intervention|OTHER: educational intervention|OTHER: physiologic testing|OTHER: management of therapy complications|BEHAVIORAL: mind-body intervention procedure|PROCEDURE: Measurement of stress-related hormones
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trial to Evaluate the Safety and Immunogenicity of PPV23 Vaccine Revaccinated in 60-70 Years Old
Status: COMPLETED
Conditions: Vaccination
Interventions: BIOLOGICAL: 23-valent pneumococcal polysaccharide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Modulation of the Intestinal Flora With the Probiotic VIVOMIXX™ in Pregnant Women at Risk of Metabolic Complications
Status: UNKNOWN
Conditions: Gestational Diabetes Mellitus in Pregnancy, Diet- Controlled|Exercise Addiction|High-Risk Pregnancy|Dietary Modification
Interventions: DIETARY_SUPPLEMENT: Probiotic VIVOMIXX™|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention of Cognitive Decline in Alzheimer's Disease by Ingested Interferon Alpha
Status: UNKNOWN
Conditions: Memory Disorders|Alzheimer's Disease
Interventions: DRUG: Aricept|DRUG: IFN-alpha2A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate TMI-358 in the Treatment of Distal Subungual Onychomycosis
Status: TERMINATED
Conditions: Distal Subungual Onychomycosis
Interventions: DRUG: TMI-358|DRUG: MMI-467
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Anti-Malarials in Incomplete Lupus Erythematosus
Status: ACTIVE_NOT_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Subjective Comparison of Pre-Lens Tear Film Stability With Daily Disposable Contact Lenses
Status: COMPLETED
Conditions: Myopia|Hyperopia|Refractive Error
Interventions: DEVICE: Nelfilcon A contact lenses|DEVICE: Omafilcon A contact lenses|DEVICE: Etafilcon A contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Subanesthetic Isoflurane/Sevoflurane in 60% Oxygen on Clinical In-vitro Experimental Sepsis
Status: UNKNOWN
Conditions: Sepsis
Interventions: DRUG: oxygen|DRUG: Sevoflurane|DRUG: Isoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Compare the Pharmacokinetics and Safety of Ramucirumab Injection With Cyramza ® in Healthy Male Volunteers
Status: COMPLETED
Conditions: Gastric Cancer|Non-small Cell Lung Cancer|Colo-rectal Cancer
Interventions: DRUG: Ramucirumab Injection|DRUG: Ramucirumab Injection [Cyramza]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Topical Antibiotic Prophylaxis in Inguinal Hernia Repair
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: DRUG: Gentamicin and cefazolin|DRUG: Cefazolin|DRUG: Gentamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Dapagliflozin Effect on FunctiOnal Mitral Regurgitation and Myocardial Remodeling
Status: RECRUITING
Conditions: Functional Mitral Regurgitation
Interventions: DRUG: Dapagliflozin|OTHER: guideline-directed medical therapy (GDMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy in Treating Patients With Newly Diagnosed Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: chlorambucil|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: fludarabine phosphate|DRUG: prednisolone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Outcomes in Arthroscopic "Inlay"Bristow Surgery With Screw Fixation vs Suture-button Fixation
Status: COMPLETED
Conditions: Shoulder; Dislocation, Chronic
Interventions: PROCEDURE: Bristow surgery fixed by the screw|PROCEDURE: Bristow surgery fixed by the suture button
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Growth and Safety of Two Partially-hydrolyzed Feeding Systems for Preterm Infants
Status: RECRUITING
Conditions: Pre-term Infant
Interventions: OTHER: Preterm formulas with HMO|OTHER: Preterm formulas without HMO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nivolumab in Treating Patients With High-Risk Kidney Cancer Before Surgery
Status: TERMINATED
Conditions: Clear Cell Renal Cell Carcinoma|Metastatic Renal Cell Carcinoma|Stage I Renal Cell Cancer AJCC v6 and v7|Stage II Renal Cell Cancer AJCC v7|Stage III Renal Cell Cancer AJCC v7|Stage IV Renal Cell Cancer AJCC v7
Interventions: PROCEDURE: Metastasectomy|PROCEDURE: Nephrectomy|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib Plus PD-1 Antibody vs TACE for Intermediate-stage HCC Beyond Up-to-seven Criteria
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Lenvatinib|DRUG: PD-1 antibody|PROCEDURE: TACE|DRUG: TACE Drug Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial for Application of Laparoscopic Total Gastrectomy With Lymph Node Dissection for Gastric Cancer (KLASS-06)
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: PROCEDURE: Radical total gastrectomy with D2 (D2 - #10) lymph node dissection by laparoscopic approach|PROCEDURE: Radical total gastrectomy with D2 (D2 - #10) lymph node dissection by open conventional approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Assessment of Arterial Dynamic Elastance in ICU Patients, Dependent on Inotropic or Vasopressor Drugs.
Status: UNKNOWN
Conditions: Sepsis|Cardiac Failure Acute
Interventions: DIAGNOSTIC_TEST: dobutamine|DIAGNOSTIC_TEST: norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Investigation of Cannabis for Chronic Pain and Palliative Care
Status: WITHDRAWN
Conditions: Chronic Pain
Interventions: DRUG: Smoked Cannabis High CBD/low THC|DRUG: Smoked Placebo Cannabis Low CBD/low THC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sepsis Electronic Prompting for Timely Intervention and Care for Inpatients
Status: ENROLLING_BY_INVITATION
Conditions: Sepsis|Electronic Health Records|Clinical Decision Support Systems
Interventions: OTHER: Nurse SIRS alert|OTHER: Prescribing clinician SIRS alert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Belatacept Therapy for the Failing Renal Allograft
Status: COMPLETED
Conditions: Failing Renal Allograft
Interventions: DRUG: Belatacept|DRUG: Calcineurin inhibitor therapy|DRUG: Mycophenolate mofetil|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Steroid Administration for Articular Fractures of the Elbow (SAFE Trial)
Status: TERMINATED
Conditions: Elbow Fracture
Interventions: DRUG: Glucocorticoids|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Endoscopic Urethral Procedures Applied After Radical Prostatectomy on Urinary Incontinence
Status: COMPLETED
Conditions: Prostate Cancer|Incontinence
Interventions: PROCEDURE: endoscopic surgical intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Progressive Neck Motor Control Exercises on Temporomandibular Joint Dysfunction
Status: NOT_YET_RECRUITING
Conditions: Temporomandibular Joint Dysfunction Syndrome
Interventions: OTHER: Progressive neck motor control exercise therapy|OTHER: Patient education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HCV Related Hepatocellular Carcinoma Recurrence After Directly Acting Antivirals: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Hepatitis C|Neoplasm Recurrence|Treatment Complication
Interventions: DRUG: Velpatasvir/Sofosbuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Feasibility Study Comparing Enteral vs Parenteral Nutritional Outcomes in Autologous Stem Cell Transplant Patients
Status: UNKNOWN
Conditions: Malignant Hematologic Neoplasm
Interventions: PROCEDURE: Parenteral Nutrition/Enteral Nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preference Study Between NovoFine® Autocover™ and a NovoFine® 8 mm Needle
Status: COMPLETED
Conditions: Diabetes|Healthcare Professionals|Delivery Systems
Interventions: DEVICE: NovoFine® needle 8 mm|DEVICE: autocover needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Sedation Strategies on Hospital LOS and ICU LOS in Patients Cardiac Surgery
Status: COMPLETED
Conditions: Sedation Complication
Interventions: DRUG: Propofol injection|DRUG: Dexmedetomidine injection|DRUG: Dexmedetomidine and Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study on a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Compared to a Meningococcal Reference Vaccine, and When Given Alone or With Two Other Vaccines in Healthy Adolescents
Status: COMPLETED
Conditions: Meningococcal Immunisation|Healthy Volunteers
Interventions: BIOLOGICAL: Meningococcal Polysaccharide (Serogroups A, C, Y, and W) Tetanus Toxoid Conjugate Vaccine (MenACYW Conjugate vaccine)|BIOLOGICAL: Meningococcal group A, C, W-135, and Y conjugate vaccine|BIOLOGICAL: Human Papillomavirus 9-valent Vaccine (9vHPV)|BIOLOGICAL: Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed Combined with Inactivated Poliomyelitis Vaccine (Tdap-IPV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Fexofenadine Hydrochloride Orally Disintegrated Tablets 30 mg Under Fasting Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fexofenadine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lacosamide IV and EEG/EKG (LIVE) Study
Status: TERMINATED
Conditions: Focal Epilepsy
Interventions: DRUG: Lacosamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Harnessing Alternative Resources to Aid Kenyans With Acute Illness
Status: UNKNOWN
Conditions: Cardiorespiratory Failure
Interventions: DEVICE: Nurse-performed Focused cardiac ultrasound (FoCUS)|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Optimization of a Tool for Predicting Postoperative Clinical Evolution After Lumbar Surgery
Status: COMPLETED
Conditions: Spine Disease|Spinal Fusion|Surgery|Spine Degeneration
Interventions: DIAGNOSTIC_TEST: SuMO Patient
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Methadone-Dolutegravir (DTG - GSK1349572) Drug Interaction Study.
Status: COMPLETED
Conditions: Infections, Human Immunodeficiency Virus and Hepatitis
Interventions: DRUG: Dolutegravir|DRUG: Methadone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: MK-8189 Safety and Tolerability in Participants With Alzheimer's Disease With or Without Symptoms of Agitation-Aggression and/or Psychosis (MK-8189-017)
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: MK-8189|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Simultaneous Lengthening of Bilateral Femora and Tibiae in Achondroplastic Patients
Status: COMPLETED
Conditions: SHOX Gene With Short Stature
Interventions: PROCEDURE: Lengthening over nail
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: N-3 Fatty Acids for the Prevention of Atrial Fibrillation in Patients With Acute Heart Failure
Status: UNKNOWN
Conditions: Acute Heart Failure|Acute Myocardial Infarction
Interventions: DRUG: Epadel, Eicosapentaenoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Cognitive Fatigue on Heart Rate Variability and Skin Conductance
Status: RECRUITING
Conditions: Cognitive Fatigue|Mental Fatigue|Behavioral Performance|Heart Rate Variability|Skin Conductance
Interventions: OTHER: Baseline|OTHER: Fatigue Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Benefit of Octagam 5%® in Subjects With Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)
Status: UNKNOWN
Conditions: Pediatric Acute-Onset Neuropsychiatric Syndrome|Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections
Interventions: BIOLOGICAL: IVIG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Engagement With an Adaptive Mobile Health Smoking Cessation Intervention
Status: COMPLETED
Conditions: Tobacco Use Cessation
Interventions: BEHAVIORAL: Brief telephone advice plus tailored text messages|DRUG: Mailed nicotine replacement therapy|BEHAVIORAL: Proactive telephone coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of PDRN in Post-operative Scars
Status: COMPLETED
Conditions: Scar
Interventions: PROCEDURE: Polydeoxyribonucleotide (PDRN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Active Controlled Trial of CHF5993 Pressurized Metered-dose Inhaler ( pMDI) vs Symbicort®Turbuhaler® in Patients With Chronic Obstructive Pulmonary Disease ( COPD)
Status: COMPLETED
Conditions: COPD (Chronic Obstructive Pulmonary Disease)
Interventions: DRUG: CHF 5993 100/6/12.5 µg|DRUG: 160 µg budesonide + 4.5 µg formoterol fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of SCT800 in Prophylaxis Therapy on Previous Treated Patients With Severe Hemophilia A
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: Recombinant Human Coagulation FVIII
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Changes of Masticatory / Swallowing Functions and Oropharyngeal Muscle Mass on Sonography After Comprehensive Swallowing Training and Tongue - Pressure Resistance Training in Stroke Patients With Dysphagia
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: swallowing therapy|OTHER: IOPI therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of the Effect of Laser on Reversing Chronic Radiation Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Radiation Dermatitis
Interventions: DEVICE: Fractional CO2 laser treatment|OTHER: No treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerability Study of Panosyl Isomaltooligosaccharides (PIMO), in Subjects With Chronic Idiopathic Constipation (CIC)
Status: COMPLETED
Conditions: Constipation Chronic Idiopathic
Interventions: DIETARY_SUPPLEMENT: MHS 1031|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Risedronate in Preventing Bone Loss in Premenopausal Women Receiving Chemotherapy for Primary Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Osteoporosis
Interventions: DIETARY_SUPPLEMENT: calcium carbonate|DIETARY_SUPPLEMENT: vitamin D|DRUG: risedronate sodium|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Compare the Safety and Efficacy of Dapagliflozin Plus Metformin Versus Sitagliptin Plus Metformin for Treatment of Diabetes in Patients With Compensated and Stable Decompensated Cirrhosis
Status: NOT_YET_RECRUITING
Conditions: Compensated Cirrhosis|Decompensated Cirrhosis
Interventions: DRUG: Metformin|DRUG: Sitagliptin|DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conversion to Sirolimus: Effects in Cytomegalovirus Infection Recurrence
Status: UNKNOWN
Conditions: Cytomegalovirus Infections
Interventions: DRUG: Drug conversion to sirolimus|DRUG: Maintenance of the current regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: MR/TRUS Fusion Guided Prostate Biopsy - An Improved Way to Detect and Quantify Prostate Cancer
Status: RECRUITING
Conditions: Prostate Disease|Elevated Prostate Specific Antigen|Family History of Prostate Cancer|Positive Digital Rectal Exam|Prostate Cancer
Interventions: OTHER: Prostate Biopsy|OTHER: MR US Fusion Guided Prostate Biopsy|DEVICE: MR/TRUS Fusion Guided Prostate Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of a Zeaxanthin Intervention on Visuomotor Function
Status: COMPLETED
Conditions: Behavior and Behavior Mechanisms
Interventions: DIETARY_SUPPLEMENT: zeaxanthin|DIETARY_SUPPLEMENT: combinatory supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Written Document to Assist Family During Decision of Withholding and Withdrawing Life-sustaining Therapies in the Intensive Care Unit
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: OTHER: Explaining withholding and withdrawing life-sustaining therapies along with a written document|OTHER: Explaining withholding and withdrawing life-sustaining therapies following standard procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: QR-Bromocriptine as an Adjunct to Insulin and Metformin in the Treatment of Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: QR-bromocriptine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Immunogenicity of an HIV Vaccine (gp145 C.6980) in Healthy, HIV-Uninfected Adults in the United States
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: gp145 C.6980 Vaccine|BIOLOGICAL: Placebo|BIOLOGICAL: Aluminum Hydroxide Adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Addition of Dexmedetomidine During Ultrasound Guided Bilateral Single Shot Erector Spinae Plane Block in Patients Undergoing Posterior Lumbar Interbody Fusion Under General Anesthesia
Status: COMPLETED
Conditions: Double Level Lumbar Spondylolisthesis (L3-L5)|Posterior Lumbar Interbody Fusion (PLIF)|Lumbar Fixation Surgery
Interventions: DRUG: Ultrasound Guided Bilateral single shot Erector Spinae Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Low-dose Buprenorphine Initiation for Opioid Use Disorder
Status: RECRUITING
Conditions: Opioid Use Disorder
Interventions: DRUG: buprenorphine-naloxone|DRUG: buprenorphine-naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of Evinacumab in Pediatric Patients With Homozygous Familial Hypercholesterolemia
Status: COMPLETED
Conditions: Homozygous Familial Hypercholesterolemia
Interventions: DRUG: Evinacumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trametinib Combined With Everolimus and Lenvatinib for Recurrent/Refractory Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor, Adult|Hepatocellular Carcinoma
Interventions: DRUG: Combination of three inhibitors Trametinib, Everolimus and Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Output Measurement in Pediatric Intensive Care Unit by Metabolic Monitor (Fick Method) (PEDIA-FICK-ICU)
Status: RECRUITING
Conditions: Intensive Care Units, Pediatric
Interventions: DIAGNOSTIC_TEST: Fick's method|DIAGNOSTIC_TEST: Echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trial to Evaluate the Time Point of Anti-VEGF Pretreatment of PDR Based on Intraoperative FFA
Status: RECRUITING
Conditions: The Condition of Fundus Neovascularization
Interventions: OTHER: Time
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC