pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of the Effect of a Nasal Allergen Challenge With Dermatophagoides Farinae Extract on Nasal Airway Inflammation in Allergic Individuals, Comparing E-cigarette Users to Cigarette Smokers and Non-smokers.
Status: TERMINATED
Conditions: Healthy Participants|Tobacco Smokers
Interventions: BIOLOGICAL: Der f
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Intermittent Pressure in Patients With PAD
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Active Intermittent Negative Pressure (INP)|DEVICE: Placebo Intermittent Negative Pressure (INP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Contrast-enhanced Ultrasound Imaging for the Early Estimate of Bevacizumab Effect on Colorectal Cancer Liver Metastases
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DEVICE: real-time contrast-enhanced ultrasound imaging (CEUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Celecoxib Effects on Amlodipine in Subjects With Existing Hypertension Requiring Antihypertensives
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: OE 10 mg amlodipine besylate tablet|DRUG: OE 200 mg celecoxib capsule|DRUG: Matched placebo for OE amlodipine besylate tablet|DRUG: Matched placebo for OE celecoxib capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of the Effect of Timing of Cholecystectomy During Initial Admission for Mild Gallstone Pancreatitis
Status: COMPLETED
Conditions: Pancreatitis
Interventions: PROCEDURE: Early cholecystectomy with IOC|PROCEDURE: Late cholecystectomy with IOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of STA-4783 in Combination With Weekly Paclitaxel for Treatment of Patients With Soft Tissue Sarcomas
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: STA-4783
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Tocilizumab for Severe RP-ILD Secondary to Systemic Diseases
Status: UNKNOWN
Conditions: Rapid Progressive Interstitial Lung Diseases
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Analysis and Oncological Outcomes in HoLERT vs TURBT
Status: RECRUITING
Conditions: Bladder Urothelial Carcinoma|Bladder Cancer
Interventions: PROCEDURE: Monopolar Transurethral resection of bladder tumor|PROCEDURE: Holmium Laser resection of bladder tumor (HoLEBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gefitinib and PEG-Interferon Alfa-2a in Treating Patients With Unresectable or Metastatic Skin Cancer
Status: UNKNOWN
Conditions: Non-melanomatous Skin Cancer
Interventions: BIOLOGICAL: PEG-interferon alfa-2a|DRUG: gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Problem Management Plus in Pregnant Women With HIV in Kenya
Status: RECRUITING
Conditions: Human Immunodeficiency Virus
Interventions: BEHAVIORAL: In-Person Program Management Plus (PM+)|BEHAVIORAL: Mobile Program Management Plus (mHealth PM+)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Baricitinib in Sjogren's Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Sjogren's Syndrome
Interventions: DRUG: Baricitinib|DRUG: Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Cetuximab in Patients With Advanced or Metastatic Biliary Tract Cancer: A Multicenter Phase II Study
Status: COMPLETED
Conditions: Time to Progression
Interventions: DRUG: gemcitabine + cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidural Morphine for Analgesia After Traumatic Vaginal Delivery
Status: WITHDRAWN
Conditions: Traumatic Vaginal Delivery
Interventions: DRUG: Morphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Direct Pulp Capping With MTA and Calcium Hydroxide.
Status: COMPLETED
Conditions: Reversible Pulpitis
Interventions: PROCEDURE: Direct Pulp Capping with Ca(OH)2|PROCEDURE: Direct Pulp Capping With MTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of "Pick'n Roll" Single-incision Laparoscopic Cholecystectomy Technique, and Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Cholelithiasis
Interventions: PROCEDURE: Four port laparoscopic cholecystectomy|PROCEDURE: SILC-Pick'n roll-Beginning (group I)|PROCEDURE: SILC-Pick'n roll-Experienced (group II)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smoking Prevention Through Social Connections Among Adolescents - ASPIRE
Status: COMPLETED
Conditions: Tobacco Use Behavior
Interventions: BEHAVIORAL: Surveys|BEHAVIORAL: ASPIRE|BEHAVIORAL: GSA-ASPIRE-Network
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Remediation for Neuropsychological Impairment in Compulsive Hoarding
Status: COMPLETED
Conditions: Hoarding Disorder|Attentional Impairment
Interventions: BEHAVIORAL: Cognitive Remediation|BEHAVIORAL: Control (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Electroacupuncture and Auricular Acupuncture for Persistent Insomnia
Status: COMPLETED
Conditions: Insomnia
Interventions: PROCEDURE: Acupuncture plus auricular acupuncture|PROCEDURE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incidence of Patellar Crepitus in Removal and Non-removal of Fibrosynovial Tissue at Superior Pole of Patella
Status: UNKNOWN
Conditions: Removal of Fibrosynovial Tissue|Non-removal of Fibrosynovial Tissue|Patellar Non-resurfacing
Interventions: PROCEDURE: Removal of fibrosynovial tissue|PROCEDURE: Non-removal of fibrosynovial tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DRUG: Semaglutide|DRUG: Placebo (semaglutide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of N-Acetylcysteine in the Treatment of Repetitive and Self-Injurious Behaviors in Cornelia de Lange Syndrome
Status: NOT_YET_RECRUITING
Conditions: Cornelia de Lange Syndrome
Interventions: DRUG: N-acetyl cysteine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Azacitidine 300 mg Film-Coated Tablets in Adult Patients With Acute Myeloid Leukaemia (AML)
Status: RECRUITING
Conditions: Acute Myeloid Leukaemia
Interventions: DRUG: Azacitidine|DRUG: Onureg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Immunotherapy of CD8+NKG2D+ AKT Cell With Chemotherapy to Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: BIOLOGICAL: CD8+NKG2D+ AKT Cell|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of [11C]Acetate-PET in LAM and TSC
Status: RECRUITING
Conditions: Lymphangioleiomyomatosis|Tuberous Sclerosis Complex
Interventions: DRUG: [11C]acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: tACS Intervention for Methamphetamine Addiction
Status: COMPLETED
Conditions: Methamphetamine-dependence
Interventions: DEVICE: transcranial alternating current stimulation|DEVICE: sham tACS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Copanlisib in Combination With Romidepsin in Patients With Relapsed or Refractory Mature T-cell Lymphoma
Status: WITHDRAWN
Conditions: Lymphoma, T-Cell
Interventions: DRUG: Copanlisib|DRUG: Romidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Rapid Recognition of Corticosteroid Resistant or Sensitive Sepsis
Status: RECRUITING
Conditions: Sepsis
Interventions: DRUG: Administration procedures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bendamustine Combined With Rituximab for Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: bendamustine|DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mavrilimumab in Severe COVID-19 Pneumonia and Hyper-inflammation (COMBAT-19)
Status: UNKNOWN
Conditions: Covid-19|Acute Respiratory Failure|ARDS, Human|Sars-CoV2|Viral Pneumonia
Interventions: DRUG: Mavrilimumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PRO95780 in Combination With Cetuximab and Irinotecan Chemotherapy or the FOLFIRI Regimen With Bevacizumab in Patients With Previously Treated Metastatic Colorectal Cancer (APM4187g)
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: bevacizumab|DRUG: cetuximab|DRUG: FOLFIRI regimen|DRUG: irinotecan|DRUG: PRO95780
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Noninvasive Hemoglobin, Comparison of PVI to Standard Methods, and Validation of Clinical Efficacy of ORI
Status: COMPLETED
Conditions: Surgery
Interventions: DEVICE: Masimo Pulse CO-Oximeter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mesenchymal Stem Cells for the Treatment of Rectovaginal Fistulas in Participants With Crohn's Disease
Status: UNKNOWN
Conditions: Rectovaginal Fistula|Crohn Disease|Crohn Disease of Vulva|Rectolabial; Fistula
Interventions: DRUG: Mesenchymal Stem Cells|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Trial of ZM008 as Single Agent and in Combination With Pembrolizumab in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Esophageal Cancer|Head and Neck Squamous Cell Carcinoma|Pancreas Adenocarcinoma|Biliary Tract Cancer|Prostate Cancer|Urothelial Carcinoma|Colorectal Cancer|Triple Negative Breast Cancer|High Grade Ovarian Serous Adenocarcinoma|Diffuse Large B Cell Lymphoma
Interventions: BIOLOGICAL: ZM008
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intra-Tympanic Steroid With PRP Combination in Sensorineural Hearing Loss and Tinnitus.
Status: COMPLETED
Conditions: Sensorineural Hearing Loss|Tinnitus
Interventions: DRUG: Combination Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain, Psychological, and Endocannabinoid Responses to Yoga in Breast Cancer Survivors With Chemotherapy-induced Neuropathic Pain
Status: COMPLETED
Conditions: Breast Cancer|Chemotherapy-induced Peripheral Neuropathy|Neuropathic Pain
Interventions: BEHAVIORAL: Aerobic exercise|BEHAVIORAL: Iyengar yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Follow-up of Patients After Knee Arthrodesis With an Intramedullary Nail
Status: COMPLETED
Conditions: Knee Arthrodesis With Intramedullary Nail
Interventions: PROCEDURE: History taken and clinical examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Galunisertib (LY2157299) Plus Stereotactic Body Radiotherapy (SBRT) in Advanced Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: ADVANCED HEPATOCELLULAR CARCINOMA (HCC)
Interventions: DRUG: Galunisertib 150mg by mouth twice a day|RADIATION: Stereotactic Body Radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radium Ra 223 With Enzalutamide Compared to Enzalutamide Alone in Men With Metastatic Castration Refractory Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Radium Ra 223 Dichloride|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bisphosphonates for the Treatment of Seropositive Musculoskeletal Complaints
Status: UNKNOWN
Conditions: Seropositive Muskuloskeletal Complaints
Interventions: DRUG: Zoledronic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fish Collagen Peptide Food Supplement on Weight and Body Composition
Status: COMPLETED
Conditions: Weight Management|Food Complement
Interventions: DIETARY_SUPPLEMENT: Placebo supplement|DIETARY_SUPPLEMENT: Naticol supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-closure of Alveoli After Avulsion of Wisdom Teeth
Status: COMPLETED
Conditions: Wisdom Tooth Avulsion
Interventions: PROCEDURE: Suturing of lower alveoli|PROCEDURE: Non suturing of lower alveoli
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Early Mobilization on Length of Stay, Recovery and Readmission Rate of Patients After CABG or AVR/MVR Surgery
Status: COMPLETED
Conditions: Coronary Artery Disease|Aortic Valve Disease|Mitral Valve Disease
Interventions: PROCEDURE: Intensive early mobilization techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Natural Killer(NK) Cell Combined With Programmed Death-1(PD-1) Antibody as Second Line Therapy for Advanced Driver Mutation Negative Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: COMBINATION_PRODUCT: NK cell and PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real-time Intraoperative Breast Cancer Visualization for Margin Assessment
Status: RECRUITING
Conditions: Breast Cancer|Cancer of the Breast
Interventions: DRUG: LS301|DEVICE: Cancer Vision Goggles and standard fluorescence imaging systems|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Enhancing the Benefits of Blueberry Polyphenols With Protein
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DIETARY_SUPPLEMENT: Blueberries|DIETARY_SUPPLEMENT: Blueberries and Whey Protein|DIETARY_SUPPLEMENT: Blueberries and Pea Protein|DIETARY_SUPPLEMENT: Blueberries and Hemp Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate Efficacy/Safety of 4 Doses of CHF5259 Via Dry Powder Inhaler (DPI) in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: CHF5259 or Placebo administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation on Using Personal Face Masks With Spectacles Versus Contact Lenses
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: somofilcon A Daily Disposable Contact Lens|DEVICE: Single Vision Spectacle for Vision Correction|OTHER: Personal Facemask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Immunoglobulins as Effective Treatment in Sydenham's Chorea
Status: COMPLETED
Conditions: Sydenham Chorea|Post Streptococcal Movement Disorder
Interventions: BIOLOGICAL: Intravenous immunoglobulin|DRUG: standard interventions penicillin VK and haloperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Online Mindful Self-Compassion Training for Medical Students: An Exploratory Feasibility Study
Status: NOT_YET_RECRUITING
Conditions: Self-Compassion
Interventions: BEHAVIORAL: Self-compassion intervention (Self-Compassion for Healthcare Communities course)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Fluvastatin on Proinflammatory and Prothrombotic Markers in Antiphospholipid Syndrome Patients
Status: COMPLETED
Conditions: Antiphospholipid Syndrome
Interventions: DRUG: Fluvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Interdental Brush Dipped in 0.2% Hyaluronic Acid Gel on Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: DEVICE: Interdental brush+HA|DEVICE: Interdental brush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TQB2450 Solution for Injection (TQB2450)+Paclitaxel+Cisplatin ± Anlotinib in the Treatment of Esophageal Cancer.
Status: UNKNOWN
Conditions: Esophageal Neoplasms
Interventions: DRUG: Paclitaxel + Cisplatin + TQB2450 injection+ Anlotinib|DRUG: Paclitaxel + Cisplatin + TQB2450 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selective Unilateral Spinal Anesthesia Versus Selective Sensory Spinal Anesthesia for Knee Arthroscopy Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: hypobaric levobupivacaine with fentanyl|DRUG: hyperbaric bupivacaine 0,5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Diagnostic of Hepatic Fibrosis With the in Severe Obese Patients Candidates to Bariatric Surgery
Status: COMPLETED
Conditions: Steatosis|Obesity|Fibrosis, Liver
Interventions: DEVICE: Evaluation of the Diagnostic of Hepatic Fibrosis With the XL Probe of the Fibroscan Versus Biopsies in Severe Obese Patients Candidates to Bariatric Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: E3-Hormone Refractory Prostrate Cancer Taxotere Combination
Status: COMPLETED
Conditions: Prostate Cancer|Metastatic|Hormone Refractory
Interventions: DRUG: Zactima (vandetanib)|DRUG: Docetaxel|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The CareWell-programme for Community-dwelling Frail Elderly Persons.
Status: COMPLETED
Conditions: Overall Functioning|Incremental Cost-effectiveness Ratio
Interventions: OTHER: The CareWell programme
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of TILs in Treatment of Patients With Advanced or Metastatic Refractory Gynecological Cancer
Status: NOT_YET_RECRUITING
Conditions: Tumor Infiltrating Lymphocytes
Interventions: BIOLOGICAL: Autologous tumor-infiltrating lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sodium Glucose Co-transporter 2 Inhibitors on Left Atrial Remodeling
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: Sodium Glucose Co-transporter 2 (SGLT2) Inhibitor|DRUG: Rhythm control and anticoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of TAK-875 in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: TAK-875|DRUG: TAK-875|DRUG: TAK-875|DRUG: TAK-875|DRUG: TAK-875|DRUG: Glimepiride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Progressive Resistance Strength Training (PRT) in Hospitalised Elderly Patients
Status: COMPLETED
Conditions: Medical Diseases|Neurological Diseases|Chronical Obstructive Lung Diseases
Interventions: OTHER: Progressive Resistance strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Monoclonal Antibody Therapy in Treating Patients With Metastatic Cancer of the Pancreas
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: HLA Screening in Reducing the Risk of Antiepileptic Drug-induced Cutaneous Adverse Reactions
Status: UNKNOWN
Conditions: Epilepsy|Neuropathy|Psychiatric Illness|Blepharospasm
Interventions: DIAGNOSTIC_TEST: HLA screening before commencing aromatic AEDs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Cervical Lordosis Rehabilitation for Nerve Root Function and Pain in Cervical Spondylotic Radiculopathy
Status: COMPLETED
Conditions: Cervical Lordosis Rehabilitation
Interventions: OTHER: Stretching exercises|OTHER: Two way traction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Third Party Donor Derived CMVpp65 Specific T-cells for The Treatment of CMV Infection or Persistent CMV Viremia After Allogeneic Hematopoietic Stem Cell Transplantation
Status: COMPLETED
Conditions: CMV Infection|Persistent CMV Viremia
Interventions: BIOLOGICAL: CMVpp65 Specific T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Compare the Outcome of Localised Varicosity Compression for 24 Hours and 5 Days After Foam Sclerotherapy to Truncal Varices
Status: COMPLETED
Conditions: Varicose Veins
Interventions: DEVICE: Compression bandaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of NV1FGF in Patients With Severe Peripheral Artery Occlusive Disease
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DRUG: XRP0038 (NV1FGF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Improving Patient Understanding in Preoperative Informed Consent Process of Trauma Patients Using a Mixed Reality Viewer
Status: RECRUITING
Conditions: Distal Radius Fractures|Ankle Fractures|Proximal Humeral Fracture
Interventions: DEVICE: Mixed Reality Viewer|DEVICE: X-ray or CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intersession Processes in Psychotherapeutic Treatments Using an Ecological Momentary Assessment Approach (ISA-Bell)
Status: RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: Cognitive Behavioural Therapy (CBT)|OTHER: Ecological Momentary Assessment (EMA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Phase II Clinical Trial on the Efficacy of Axitinib as a Monotherapy or in Combination With Lomustine for the Treatment of Patients With Recurrent Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: axitinib|DRUG: Axitinib plus Lomustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3BNC117 and 10-1074 in HIV-infected Individuals
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV)
Interventions: DRUG: 3BNC117|DRUG: 10-1074|OTHER: Analytical treatment interruption|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Interventional Extension to Investigate Recurrence of Vulvovaginal Candidiasis and Candida Colonization
Status: COMPLETED
Conditions: Candidiasis, Vulvovaginal|Yeast Infection|Mycoses|Moniliasis, Vulvovaginal|Vaginitis, Monilial
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of PHN-010 in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Lung Cancer|Colon Cancer|Endometrial Cancer|Ovarian Cancer|Cervical Cancer|Advanced Solid Tumor|Advanced Cancer
Interventions: DRUG: PHN-010
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron Reduction for the Treatment of Diabetes and Nonalcoholic Fatty Liver Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Iron|Diabetes|Nonalcoholic Fatty Liver
Interventions: PROCEDURE: Blood Donation|PROCEDURE: Sham Blood Donation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Inebilizumab Efficacy and Safety in IgG4- Related Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: IgG4 Related Disease
Interventions: DRUG: Inebilizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Upper Extremity Exoskeleton to Target Unwanted Joint Synergies During Repetitive Training in Stroke Survivors
Status: RECRUITING
Conditions: Acute Stroke
Interventions: OTHER: SA controller|OTHER: TA controller|OTHER: SA controller early testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic Testing for Men With Metastatic Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Prostate Carcinoma|Stage IV Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Genetic Counseling|OTHER: Genetic Testing|OTHER: Laboratory Biomarker Analysis|BEHAVIORAL: Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EDG004 Treatment of Adult Patients With Generalized Anxiety Disorder (GAD)
Status: COMPLETED
Conditions: Generalized Anxiety Disorder (GAD)
Interventions: DRUG: Extended-release lorazepam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Use of Tenapanor as Core Therapy in the Treatment of Hyperphosphatemia
Status: COMPLETED
Conditions: Chronic Kidney Disease Requiring Chronic Dialysis|Hyperphosphatemia
Interventions: DRUG: Tenapanor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Blenderized Enteral Tube Feeds on Pediatric Upper Gastrointestinal Tract Physiology
Status: RECRUITING
Conditions: Enteral Feeding Intolerance
Interventions: OTHER: Elecare Jr|OTHER: Nourish|OTHER: Real Foods Blends
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Aerobic Blood Flow Restriction
Status: ACTIVE_NOT_RECRUITING
Conditions: Occlusion of Artery|Aerobic Exercise
Interventions: DEVICE: Blood flow restriction Running on Treadmill|OTHER: Running on Treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Mepolizumab in Severe Bilateral Nasal Polyps
Status: COMPLETED
Conditions: Nasal Polyps
Interventions: DRUG: Mepolizumab|DRUG: Placebo|DRUG: Mometasone furoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, and Efficacy of BGE-175 in Hospitalized Adults With Coronavirus Disease 2019 (COVID-19) That Are Not in Respiratory Failure
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: BGE-175|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of IMT on Exercise Capacity, Dyspnea and Lung Functions in LTx
Status: COMPLETED
Conditions: Lung Transplant|Inspiratory Muscle Training
Interventions: OTHER: inspiratory muscle training|OTHER: Pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Reading to Preterm Infants on Baby and Parents' Well Being
Status: COMPLETED
Conditions: Parental Infant Bonding|Cardio-respiratory Stability in Preterm NICU Infants
Interventions: OTHER: Parental Reading Aloud
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adrenal Artery Ablation for Uncontrolled Hypertension
Status: UNKNOWN
Conditions: Uncontrolled Hypertension
Interventions: PROCEDURE: Selective endovascular chemical ablation of adrenal gland|DRUG: Traditional triple antihypertensive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Postoperative Outcomes Provided by a Continuous Preperitoneal Infusion Versus Ultrasound Guided Rectus Sheath Block for Midline Emergency Laparotomy
Status: COMPLETED
Conditions: Abdominal Pain
Interventions: PROCEDURE: an ultrasound guided rectus sheath block|PROCEDURE: multiholed catheter|PROCEDURE: an ultrasound guided rectus sheath block &multiholed catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Antecedent Metabolic Health and Metformin Aging Study
Status: RECRUITING
Conditions: Aging|Insulin Sensitivity|Chronic Disease|Mitochondria|Insulin Resistance
Interventions: DRUG: Metformin|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Family-mismatched/Haploidentical Donors Versus Matched Unrelated Donors
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Transplants from 8/8-matched Unrelated donors|DRUG: Transplants from family-mismatched/haploidentical donors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficiency of Stent-based Diverting Technique Versus Ileostomy in Rectal Cancer Patients
Status: RECRUITING
Conditions: Rectal Neoplasms
Interventions: PROCEDURE: Stent-based Diverting Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intercostal Nerve Cryoablation for Postoperative Pain Management
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DEVICE: Intercostal Nerve Cryoablation|DRUG: Bupivacaine liposomal injectable suspension|DRUG: Patient-controlled analgesia (PCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of nanOss Bioactive 3D in the Posterolateral Spine
Status: COMPLETED
Conditions: Degenerative Disc Disease|Spinal Stenosis|Spondylolisthesis
Interventions: DEVICE: nanOss Bioactive 3D BVF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Disease-based Treatment Study for Diagnosed Osteoarthritis Utilizing Adipose-derived Regenerative Cells
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Osteoarthritis|Hip Osteoarthritis|Ankle Osteoarthritis|Shoulder Osteoarthritis|Wrist Osteoarthritis
Interventions: DEVICE: Adipose-derived regenerative cells
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Evaluation of Remimazolam for Endoscopic Ultrasound-guided Fine Needle Aspiration/Biopsy
Status: UNKNOWN
Conditions: Endoscopic Ultrasonography-guided Fine Needle Aspiration|Sedation Complication|Remimazolam
Interventions: DRUG: Remimazolam Injection|DRUG: Propofol Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ICU Diaries and Its Effects After the Unit Discharge
Status: UNKNOWN
Conditions: Post Intensive Care Unit Syndrome|Intensive Care Unit Syndrome|PTSD|Anxiety Symptoms|Depressive Symptoms
Interventions: DEVICE: ICU Diaries
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase III Study to Evaluate the Efficacy and Safety of AK111 in Subjects With Active Ankylosing Spondylitis
Status: RECRUITING
Conditions: Ankylosing Spondylitis
Interventions: DRUG: AK111|DRUG: Placebo+AK111
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Measure the Effect of Tolterodine Extended Release on the Thickness of the Bladder Wall in Patients With Overactive Bladder
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DRUG: Tolterodine ER|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Improving Implementation of Lung Cancer Screening in Diverse Populations II
Status: COMPLETED
Conditions: Early Detection of Cancer|Lung Cancer
Interventions: OTHER: CAQ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prognostic Value of the Selvester QRS Score for Perioperative Myocardial Injury Following Non-cardiac Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiac Ischemia|Cardiac Arrhythmia|Perioperative Injury|Perioperative Complication
Interventions: DIAGNOSTIC_TEST: Selvester QRS Score with Preoperative ECG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Non-interventional Observation of Practical Implementation, Efficacy and Safety of Continuous Infusion With KOGENATE Bayer in Surgery
Status: COMPLETED
Conditions: Hemophilia A
Interventions: BIOLOGICAL: Recombinant Factor VIII (Kogenate FS, BAY14-2222)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Controlled Trial of Aliskiren in the Prevention of Major Cardiovascular Events in Elderly People
Status: TERMINATED
Conditions: Cardiovascular Events
Interventions: DRUG: Aliskiren|DRUG: Amlodipine|DRUG: Hydrochlorothiazide (HCTZ)|DRUG: Placebo for Aliskiren|DRUG: Placebo for Amlodipine|DRUG: Placebo for Hydrochlorothiazide (HCTZ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Choosing Opioid Management for Pain and Analyzing Acute Chest Syndrome (ACS) Rates Equally
Status: COMPLETED
Conditions: Pain|Sickle Cell Disease
Interventions: DRUG: Morphine|DRUG: Nubain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET Acetate for Castrate-Resistant Prostate Cancer on Chemotherapy
Status: COMPLETED
Conditions: Castrate Resistant Prostate Cancer|Prostate Cancer
Interventions: RADIATION: PET Acetate scan|DRUG: Carbon-11 labeled Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: International Substudy Enigma2 on Postoperative Cognitive Disorders
Status: TERMINATED
Conditions: Anesthesia|Delirium, Dementia, Amnestic, Cognitive Disorders
Interventions: DRUG: Nitrous Oxide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Repetitive Transcranial Magnetic Stimulation on Patients With Dysphagia in Stroke Observed Based on Functional Near-infrared Spectroscopic
Status: COMPLETED
Conditions: Stroke|Deglutition Disorders
Interventions: OTHER: routine swallowing rehabilitation|DEVICE: real repetitive transcranial magnetic stimulation|DEVICE: sham repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Selective Androgen Receptor Modulator for Symptom Management in Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: LY2452473|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Central Sensitisation and Postoperative Pain
Status: UNKNOWN
Conditions: Thoracotomy|Hyperalgesia|Hyperalgesia, Secondary|Central Sensitisation|Electroencephalography|Persistent Postsurgical Pain|Humans
Interventions: OTHER: electroencephalography (EEG)|OTHER: questionnaires|OTHER: high frequency electrical stimulation of the forearm skin (HFS)|OTHER: cutaneous mechanical pinprick stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Accelerated Atherosclerosis in High Risk Population Groups: An Assessment by Magnetic Resonance Imaging
Status: TERMINATED
Conditions: Atherosclerosis
Interventions: DRUG: Statin therapy|BEHAVIORAL: Lifestyle modification
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Efficacy / Safety of Etanercept + Methotrexate Compared to Usual Treatment in Moderate RA Subjects
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: etanercept (EnbrelTM)|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Analgesic Effects of Paracetamol/Codeine and Ibuprofen on Pain After Third Molar Surgery
Status: COMPLETED
Conditions: To Control Pain After Third Molar Surgery
Interventions: DRUG: paracetamol 500 mg plus codeine 30 mg preoperative administration|DRUG: ibuprofen 400 mg preoperative administration|DRUG: Placebo oral tablet preoperative administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for Moderate Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: Flexsure Capsules|DIETARY_SUPPLEMENT: Placebo Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CBD Effects on Forehead Split Scar Healing
Status: NOT_YET_RECRUITING
Conditions: Forehead; Wound
Interventions: BIOLOGICAL: Group 1 cannabidiol (CBD) oil with silicone ointment|BIOLOGICAL: Group 2 cannabidiol (CBD) oil with silicone ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Poziotinib in Patients With Epidermal Growth Factor Receptor (EGFR) or Human Epidermal Growth Factor Receptor 2 (HER2) Activating Mutations in Advanced Malignancies
Status: TERMINATED
Conditions: Breast Cancer|Colorectal Cancer|Solid Tumor|Glioblastome Multiforme
Interventions: DRUG: Poziotinib Hydrochloride|DRUG: Loperamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized PRRT of Neuroendocrine Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Tumors|Carcinoid Tumor|Carcinoma, Neuroendocrine
Interventions: DRUG: 177Lu-Octreotate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auto-PAP for Pulmonary Hypertension Treatment in Decompensated HF Patients With Sleep Apnea.
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Hypertension, Pulmonary|Heart Failure
Interventions: DEVICE: AirSense™ 10 AutoSet|OTHER: Standard Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia
Status: COMPLETED
Conditions: Homozygous Familial Hypercholesterolemia (HoFH)
Interventions: DRUG: Rosuvastatin 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Gel Aromatherapy on Pain for Patients With De Quervain Disease
Status: RECRUITING
Conditions: De Quervain Disease
Interventions: DRUG: Diclofenac gel|DRUG: Aromatherapy gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: International Registry for Patients With Castleman Disease
Status: RECRUITING
Conditions: Castleman Disease|Castleman's Disease|Giant Lymph Node Hyperplasia|Angiofollicular Lymph Hyperplasia|Angiofollicular Lymph Node Hyperplasia|Angiofollicular Lymphoid Hyperplasia|GLNH|Hyperplasia, Giant Lymph Node|Lymph Node Hyperplasia, Giant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antibiotic Treatment of Recurrent Episodes of Asthma in Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Childhood Asthma With Acute Exacerbation
Interventions: DRUG: Azithromycin|OTHER: Placebo mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT