pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The NORDSTEN Studies/ The Spinal Stenosis Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Lumbar Spinal Stenosis
Interventions: PROCEDURE: Bilateral laminotomy (BL)|PROCEDURE: Unilateral laminotomy with crossover (UL)|PROCEDURE: Spinous Process Osteotomy (SPO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Comparison of LMA (Laryngeal Mask Airway) Supreme and LMA Proseal in Infants Below 10kg
Status: COMPLETED
Conditions: Laryngeal Mask Airway
Interventions: DEVICE: LMA Supreme|DEVICE: LMA Proseal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Autologous Peripheral Blood Stem Cell Transplantation With In Vivo Purging as an Alternate Stem Cell Transplantation Program for Pts w/AML in 1st & 2nd Complete Remission w/no HLA Matched Related Donor
Status: COMPLETED
Conditions: Leukemia, Monocytic, Acute
Interventions: DRUG: Autologous peripheral Bld Stem Cell Transplantation with In Vivo Purging as an alternate stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study on Modified Delta-shaped Gastroduodenostomy in Totally Laparoscopic Surgery for Distal Gastric Cancer
Status: UNKNOWN
Conditions: Stomach Neoplasms
Interventions: PROCEDURE: Totally laparoscopic distal gastrectomy|PROCEDURE: Laparoscopy-assisted distal gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Reliance on Historical Blood Eosinophil Counts on ICS Prescribing by GOLD 2019 Thresholds in COPD
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Blood Eosinophil counts - comparing historical with stable state
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating the Safety, Efficacy and Tolerability of BIO89-100 in Subjects With Biopsy-confirmed Nonalcoholic Steatohepatitis (NASH)
Status: ACTIVE_NOT_RECRUITING
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: BIO89-100|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antisense102: Pilot Immunotherapy for Newly Diagnosed Malignant Glioma
Status: COMPLETED
Conditions: Malignant Glioma|Neoplasms
Interventions: DRUG: IGF-1R/AS ODN; Surgery with tissue harvest and implantation 20 diffusion chambers in the rectus sheath with IGF-1R/AS ODN within 24 hours of craniotomy, implanted for 48 hours.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Theta-burst Stimulation (TBS) in Patients With Major Depression
Status: COMPLETED
Conditions: Depression
Interventions: DEVICE: Thetaburst Stimulation|DEVICE: High frequency rTMS|DEVICE: Placebo Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Survival With Olanzapine in Patients With Locally Advanced or Metastatic Upper Gastrointestinal and Lung Cancer
Status: RECRUITING
Conditions: Advanced Cancer|Olanzapine|Progression Free Survival
Interventions: DRUG: Olanzapine 2.5 MG|DRUG: Standard anti-tumor treatment|DIETARY_SUPPLEMENT: Nutritional advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Darolutamide + Consolidation Radiotherapy in Advanced Prostate Cancer Detected by PSMA
Status: RECRUITING
Conditions: Advanced Prostate Carcinoma|Cancer of Prostate|PSA|Castrate Resistant Prostate Cancer
Interventions: DRUG: Darolutamide|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Validation of "Ready-to-Use" Inhalable Forms of Hydroxychloroquine for Treatment of COVID-19
Status: UNKNOWN
Conditions: Covid19|Hydroxychloroquine Adverse Reaction
Interventions: DRUG: inhalable hydroxychloroquine (HCQ)|DRUG: supportive and symptomatic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Learn What Happens to Different Medicinal Forms of BAY2328065 When They Enter the Body and How Safe They Are in Healthy Male and Female Participants
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: BAY2328065|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving TRansitions ANd OutcomeS for Heart FailurE Patients in Home Health CaRe (I-TRANSFER-HF): A Type 1 Hybrid Effectiveness- Implementation Trial
Status: RECRUITING
Conditions: Heart Failure
Interventions: OTHER: I-TRANSFER-HF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: CareToy - A Modular Smart System for Infants' Rehabilitation at Home Based on Mechatronic Toys
Status: COMPLETED
Conditions: Preterms at Risk for Developmental Disorders
Interventions: DEVICE: CareToy|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of High-Dose Quadrivalent Influenza Vaccine (Efluelda®) Versus Standard-Dose (QIV-SD), in Subjects 65 Years of Age and Older on Innate Immunity, Including Gene Expression
Status: COMPLETED
Conditions: Vaccine Reaction
Interventions: BIOLOGICAL: Experimental arm : High-Dose Quadrivalent Influenza Vaccine (Efluelda)|BIOLOGICAL: Active Comparator: Standard-Dose Quadrivalent Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Feasibility Study of Neurofeedback for Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DEVICE: Active Neurofeedback|DEVICE: Sham neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Clinical Study of LCB01-0371 to Evaluate the EBA, Safety and PK
Status: COMPLETED
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: LCB01-0371 800mg, QD|DRUG: LCB01-0371 400mg, BID|DRUG: LCB01-0371 800mg, BID|DRUG: Tubes 3~5Tablet, QD|DRUG: Zyvox 600mg, BID|DRUG: LCB01-0371 1200mg, QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAR-T Cell Immunotherapy in CD19 Positive Relapsed or Refractory Leukemia and Lymphoma
Status: UNKNOWN
Conditions: Acute Lymphocytic Leukemia|Chronic Lymphocytic Leukemia|Follicular Lymphoma|Mantle Cell Lymphoma|B-cell Prolymphocytic Leukemia|Diffuse Large Cell Lymphoma
Interventions: BIOLOGICAL: PCAR-019 (anti-CD19 CAR-T cells)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening for Risk Factors of Prediabetes Among Adult Patients at Sohag University Hospital
Status: RECRUITING
Conditions: PreDiabetes
Interventions: DIAGNOSTIC_TEST: HbA1c|DIAGNOSTIC_TEST: lipid profile|DIAGNOSTIC_TEST: CBC|DIAGNOSTIC_TEST: Alb/cr ratio|DIAGNOSTIC_TEST: serum creatinine .|DIAGNOSTIC_TEST: CRP|DIAGNOSTIC_TEST: urine analysis|DIAGNOSTIC_TEST: ECG|DIAGNOSTIC_TEST: fundus examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Epidural Analgesia on the Parameter ANI During Childbirth
Status: TERMINATED
Conditions: Labor Pain
Interventions: DRUG: NaCl 0.9%|DRUG: Sufentanil|DRUG: lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Oxycodone/Naloxone controlled-release|DRUG: Oxycodone HCl controlled-release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sodium Intake on Brain Natriuretic Peptide Levels in Patients With Heart Failure
Status: COMPLETED
Conditions: Diet, Sodium-Restricted|Heart Failure, Systolic|Natriuretic Peptide, Brain|Clinical Trial
Interventions: OTHER: Severe sodium restriction|OTHER: Moderate sodium restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Infant Feeding on Newborn Metabolomic Profile
Status: COMPLETED
Conditions: Formula Feeding of Healthy Full Term Infants|Breast Feeding of Healthy Full Term Infants
Interventions: OTHER: Infant formula with GOS, beta-palmitate, acidified milk|OTHER: Standard infant formula without functional ingredients|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Alpha-blocker Plus Diuretic Combination Therapy as Second-line Treatment for Nocturia in Men
Status: COMPLETED
Conditions: Nocturia
Interventions: DRUG: combination therapy of terazosin and hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib Plus Venetoclax in Subjects With Treatment-naive Chronic Lymphocytic Leukemia /Small Lymphocytic Lymphoma (CLL/SLL)
Status: COMPLETED
Conditions: Leukemia|Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: ibrutinib|DRUG: venetoclax|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fentanyl Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Spinal Anesthesia ; Peritoneal Symptomatic Effects
Status: RECRUITING
Conditions: Dexmedetomidine|Fentanyl
Interventions: DRUG: Dexmedetomidine Injection [Precedex]|DRUG: Fentanyl HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TRPV Expression in Subjects With Sensitive Skin
Status: UNKNOWN
Conditions: Sensitive Skin
Interventions: PROCEDURE: Skin biopsy|PROCEDURE: Oral mucosa specimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of GSK3196165 Versus Placebo and Tofacitinib in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: BIOLOGICAL: GSK3196165 (Otilimab)|DRUG: Tofacitinib 5 mg|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Operative Adjuvant Concurrent Chemoradiotherapy For High Risk Oral Cavity Squamous Cell Carcinoma Patients
Status: COMPLETED
Conditions: Oral Cavity|Squamous Cell Carcinoma
Interventions: DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics, Safety, and Antiviral Activity of JNJ-63623872 in Combination With Oseltamivir in Adult, and Elderly Hospitalized Participants With Influenza A Infection
Status: COMPLETED
Conditions: Influenza A Virus
Interventions: DRUG: JNJ-63623872|DRUG: Placebo|DRUG: Oseltamivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Direct Oral Anticoagulants for Prevention of lEft ventRIcular Thrombus After Anterior Acute Myocardial InFarction - APERITIF
Status: COMPLETED
Conditions: Myocardial Infarction, Acute|Left Ventricular Thrombus
Interventions: DRUG: Rivaroxaban 2.5 MG [Xarelto]|DRUG: DAPT strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Vaginal Cleansing With Povidone Iodine and the Risk of Post Cesarean Endometritis
Status: UNKNOWN
Conditions: Infection; Cesarean Section
Interventions: DRUG: 10% povidone iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study of the Effects of Mirabegron on Symptoms in Patients With Interstitial Cystitis
Status: TERMINATED
Conditions: Cystitis, Interstitial
Interventions: DRUG: Mirabegron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment Patterns and Key Healthcare Resource Use in Acute Myeloid Leukemia (AML) With or Without FMS-like Tyrosine Kinase-3 (FLT3) Mutation Study Based on Retrospective Chart Review
Status: COMPLETED
Conditions: Acute Myeloid Leukemia (AML)
Interventions: OTHER: Treatment patterns among AML patients|OTHER: AML-related healthcare resources
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Return to Work: Promoting Health and Productivity in Workers With Common Mental Disorders
Status: COMPLETED
Conditions: Adjustment Disorders|Anxiety Disorders|Depression
Interventions: OTHER: Acceptance and Commitment Therapy (ACT)|OTHER: workplace intervention (WPI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Gabapentin on Kidney Function Following Laparoscopic Sleeve Gastrectomy(LSG)
Status: NOT_YET_RECRUITING
Conditions: Acute Kidney Injury|Bariatric Surgery Candidate|Gabapentin
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Phase I/II Trial Investigating the Safety, Tolerability, Pharmacokinetics, Immune and Clinical Activity of SX-682 in Combination With BinTrafusp Alfa (M7824 or TGF-beta "Trap"/PD-L1) With CV301 TRICOM in Advanced Solid Tumors (STAT)
Status: COMPLETED
Conditions: Metastatic Cancer|Solid Tumors
Interventions: DRUG: SX-682|DRUG: M7824|BIOLOGICAL: MVA-BN-CV301|BIOLOGICAL: recombinant fowlpox viral (FPV)-CV301
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heart/Mediastinal Ratio Study for Potential Equivalence of Heart/Mediastinal Ratios at One and Two Hours to the Traditional Heart/Mediastinal Ratio Obtained at Four Hours
Status: UNKNOWN
Conditions: Neuroendocrine Tumor
Interventions: OTHER: Standard of care diagnostic MIBG scan for neuroendocrine tumor diagnosis.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TQB2928 Injection Combined Anlotinib Hydrochloride Capsule in Recurrent/Metastatic Osteosarcoma and Other Solid Tumors
Status: RECRUITING
Conditions: Osteosarcoma|Other Solid Tumors
Interventions: DRUG: 1200mg of TQB2928 injection+Anlotinib|DRUG: 1800mg of TQB2928 injection+Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does tDCS Improve Motor Learning in Children With DCD?
Status: COMPLETED
Conditions: Developmental Coordination Disorder
Interventions: DEVICE: Transcrainial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pazopanib Versus Temsirolimus in Poor-Risk Clear-Cell Renal Cell Carcinoma (RCC)
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: DRUG: Pazopanib|DRUG: Temsirolimus|BEHAVIORAL: Quality of Life Assessment|DRUG: Benadryl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role Of Nitazoxanide, Interferon Alfa And Ribavirin In Treatment Of Hepatitis C Infected Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Hepatitis C, Chronic|DIABETES MELLITUS Type 2
Interventions: DRUG: nitazoxanide|DRUG: conventional interferon alfa|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Oral Dose Study of F901318
Status: COMPLETED
Conditions: Invasive Aspergillosis
Interventions: DRUG: F901318 safety|DRUG: F901318 tolerability|DRUG: F901318 pharmacokinetics|OTHER: Placebo safety|OTHER: Placebo tolerability|OTHER: Placebo pharmacokinetics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Binaural Sound for Remimazolam Maintenance
Status: RECRUITING
Conditions: General Anesthesia|Prostate Cancer Stage|Uterine Myoma
Interventions: PROCEDURE: Binaural sound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Utility of ChatGPT in Pre-vasectomy Counselling in an Office-based Setting
Status: RECRUITING
Conditions: Vasectomy|Contraception
Interventions: OTHER: ChatGPT Language Model
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Qurevo Plus Ribavirin Based Therapy for Hepatitis C With or Without Cirrhosis in Haemodialysis Patients
Status: UNKNOWN
Conditions: Chronic Hepatitis c
Interventions: DRUG: Ombitasvir, Paritaprevir and Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Ranibizumab With Mitomycin C During Trabeculectomy
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Ranibizumab|DRUG: Ranibizumab and MMC|DRUG: MMC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PREVAIL-J - Transfemoral & Transapical Placement of Aortic Balloon Expandable Transcatheter Valves Trial (Japan)
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: Transcatheter aortic valve implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iloprost in Preventing Lung Cancer in Former Smokers
Status: COMPLETED
Conditions: Lung Carcinoma
Interventions: DRUG: Iloprost|OTHER: Placebo Administration|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Selenium Supplementation on Influenza Vaccination
Status: COMPLETED
Conditions: Selenium Supplementation|Influenza Vaccination
Interventions: DIETARY_SUPPLEMENT: Selenium Supplementation|BIOLOGICAL: Influenza vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: FEIBA to Optimize Postcardiopulmonary Bypass Hemostasis in Pediatric Cardiac Patients
Status: WITHDRAWN
Conditions: Cardiac Disease
Interventions: DRUG: FEIBA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled NAC in Treatment of IPF
Status: WITHDRAWN
Conditions: Idiopathic Pulmonary Fibrosis (IPF)
Interventions: DRUG: N-acetyl cysteine then Placebo|DRUG: Placebo then N-acetyl cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hidradenitis Suppurativa Study of Izokibep
Status: ACTIVE_NOT_RECRUITING
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Placebo|DRUG: Izokibep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Suvorexant (Belsomra) for the Treatment of Bipolar Depression With Insomnia
Status: WITHDRAWN
Conditions: Bipolar Disorder|Insomnia
Interventions: DRUG: Suvorexant (Belsomra)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EOTA With Or Without Mechanical Traction For Patients With Lumbar Spondylosis
Status: COMPLETED
Conditions: Lumbar Spondylosis
Interventions: OTHER: Extension Oriented Treatment Approach|OTHER: EOTA+ Traction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post Operative Pain and Oral Health Related Quality of Life Following Pulpotomy VS Extraction of Permanent First Molar
Status: NOT_YET_RECRUITING
Conditions: Irreversible Pulpitis
Interventions: PROCEDURE: MTA pulpotomy|PROCEDURE: Extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of Water Method During Insertion Phase of Flexible Sigmoidoscopy in Training
Status: COMPLETED
Conditions: Colorectal Cancer Screening
Interventions: DIAGNOSTIC_TEST: Water method group|DIAGNOSTIC_TEST: Air insufflation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: UCDCC#270: Avelumab and Stereotactic Ablative Radiotherapy in Non-responding and Progressing NSCLC Patients
Status: COMPLETED
Conditions: Metastatic Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Avelumab|RADIATION: Stereotactic ablative radiotherapy (SAR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xiyanping Injection Combined With Azithromycin VS Azithromycin for Children With pneumoniaProtozoal Pneumonia
Status: UNKNOWN
Conditions: Mycoplasma Pneumoniae Pneumonia
Interventions: DRUG: Azithromycin plus Xiyanping injection|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epidural Loading Prior to Catheter Insertion
Status: WITHDRAWN
Conditions: Administration Methods of Labor Analgesia
Interventions: PROCEDURE: Epidural loading dose|DEVICE: Epidural catheter|DEVICE: Epidural needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improving Quality of Life After Prostate Brachytherapy: a Comparison of HDR and LDR Brachytherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: HDR|RADIATION: LDR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How a Medicine That Reduces Stomach Acid Affects the Level of Sisunatovir in the Blood of Healthy Adults.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Sisunatovir|DRUG: Rabeprazole 40 mg|DRUG: Sisunatovir suspension|DRUG: Rabeprazole 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Restylane Perlane Lidocaine for Correction of Midface Volume Deficit and/or Midface Contour Deficiency
Status: COMPLETED
Conditions: Midface Volume Deficit
Interventions: DEVICE: Restylane Perlane Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effects of XXS on Oxidative Stress in Patients With Mild or Moderate Hyperlipidemia
Status: COMPLETED
Conditions: Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: XXS|DIETARY_SUPPLEMENT: non-XXS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: P6 Acupressure Before Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Postoperative Complications|Postoperative Nausea and Vomiting
Interventions: DEVICE: Acupressure Wrist Band|DEVICE: Placebo Acupressure Wrist Band
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Multiple Rising Doses of BI 425809 Tablets for 12 Days to Young and Elderly Healthy Male and Female Volunteers and Comparison of Pharmacokinetics of a Single Oral Dose of BI 425809 (Morning Versus Evening)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 425809|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Drug Excretion in Breast Milk
Status: RECRUITING
Conditions: Postpartum|Lactation|Drugs in Breast Milk|Mammary Drug Transporters|BCRP|OCT1
Interventions: DRUG: Cimetidine 200 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Changes in the Diameter of Retinal Vessels After Remote Ischemic Conditioning in Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Retinal Ischemia|Diabetes Complications|Ischemia|Diabetes Mellitus, Type 1
Interventions: OTHER: Remote Ischemic Conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: DL-3-n-butylphthalide Treatment in Patients With Mild to Moderate Alzheimer's Disease Already Receiving Donepezil
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: DL-3-n-butylphthalide|DRUG: Donepezil
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of T-DXd vs. CDK4/6i-based ET as First-line Therapy of HR-positive and HER2-low/Ultralow Advanced Breast Cancer Patients Classified as Non-luminal Subtype
Status: NOT_YET_RECRUITING
Conditions: Advanced Breast Cancer|Advanced Breast Carcinoma|Hormone Receptor Positive Breast Carcinoma
Interventions: DRUG: Trastuzumab deruxtecan (T-DXd, DS-8201a)|DRUG: CDK4/6i plus ET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Guselkumab for the Treatment of Palmoplantar-non-Pustular Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Guselkumab 100 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PET/CT Scan as a Tool to Rationalize the Treatment of of Advanced NSCLC Patients Undergoing First Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer Metastatic|Non-small Cell Lung Cancer Stage IIIB
Interventions: PROCEDURE: PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diffusion Tensor (Magnetic Resonance) Imaging and Tractography in Herniation of the Cervical Spine
Status: COMPLETED
Conditions: Cervical Spine Herniation
Interventions: OTHER: MRI-Diffusion Tensor Imaging and Tractrography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Post Operative Pain After Sonic Activation and Different Irrigation Needles During Root Canal Treatment
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DEVICE: Open ended needle irrigation|DEVICE: side vented needle irrigation|DEVICE: Sonic activation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: BUN/Cr-based Hydration Therapy to Improve Outcomes for Dehydrated Patients With Acute Ischemic Stroke.
Status: COMPLETED
Conditions: Stroke|Dehydration
Interventions: OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Meaningful Activity Intervention for Persons With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Daily Enhancement Meaningful Activity (DEMA)|BEHAVIORAL: Information Support (IS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Palbociclib in Combination With Fulvestrant or Letrozole in Patients With ER+, HER2- Advanced Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Palbociclib|DRUG: Fulvestrant|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon
Status: COMPLETED
Conditions: Breast Cancer|Chronic Myeloproliferative Disorders|Gestational Trophoblastic Tumor|Graft Versus Host Disease|Kidney Cancer|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Neuroblastoma|Ovarian Cancer|Testicular Germ Cell Tumor
Interventions: DRUG: beclomethasone dipropionate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Theophylline in the Treatment of Bronchiectasis
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: DRUG: Theophylline|DRUG: Placebo(for Theophylline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Computer-aided and Mental Trainings Induced Plasticity of Sensorimotor Cortex in Patients Born Without Upper Limbs
Status: UNKNOWN
Conditions: Amelia of Upper Limb
Interventions: BEHAVIORAL: Mental trainings|BEHAVIORAL: Computer-aided trainings|BEHAVIORAL: Computer-aided and mental trainings|OTHER: No trainings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Risk Factors for Recurrence After Pelvic Reconstruction
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: DEVICE: herniamesh|DEVICE: biological graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Diffuse Large B Cell Non-Hodgkin's Lymphoma in the Vulnerable/Frail Elderly. A Multicentric Randomized Phase II Trial
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim|BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: liposome-encapsulated doxorubicin citrate|DRUG: prednisone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myeloid Derived Suppressor Cells Clinical Assay in Finding Kidney Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Subject|Metastatic Renal Cell Cancer|Recurrent Renal Cell Carcinoma|Stage I Renal Cell Cancer|Stage II Renal Cell Cancer|Stage III Renal Cell Cancer
Interventions: PROCEDURE: Computed Tomography|OTHER: Cytology Specimen Collection Procedure|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Magnetic Resonance Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: GPS: Adaptation Trial of an HIV Prevention Counselling Program for HIV-positive and HIV-negative Gay and Bisexual Men
Status: COMPLETED
Conditions: HIV/AIDS|Sexually Transmitted Infection|Health Behavior
Interventions: BEHAVIORAL: GPS program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Vitis Vinifera Seed Extract on Venous Reflux Time in Varicose Vein
Status: RECRUITING
Conditions: Varicose Veins of Lower Limb
Interventions: DRUG: Vitis Vinifera seed extract medication plus therapeutic lifestyle change|BEHAVIORAL: Therapeutic lifestyle change only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Remimazolam and Propofol on Hemodynamic Stability in Prone Position
Status: RECRUITING
Conditions: Hemodynamic Instability
Interventions: DRUG: Remimazolam|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Parent-Child Interaction and Emotion Development Therapy in Treating Preschool Children With Depression
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Parent Child Interaction Therapy-Emotion Development (PCIT-ED)|BEHAVIORAL: Developmental Education Parenting Intervention (DEPI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Session of Anodal Cerebellar vs Cerebral Transcranial Direct Current Stimulation in Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Anodal tDCS cerebellar stimulation group|OTHER: Anodal tDCS cerebral (M1) stimulation group|OTHER: sham group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I, Open Label, Single-Dose, Four Way Crossover Study to Compare the PK of NP101 With Oral Imitrex® (50mg) in Migraine Subjects During an Acute Migraine Attack and During a Non-Migraine Period
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: Sumatriptan succinate|DRUG: NP101 Study Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Insulin Aspart Versus Glibenclamide in Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin aspart|DRUG: glibenclamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Basiliximab in Treating Patients With Newly Diagnosed Glioblastoma Multiforme Undergoing Targeted Immunotherapy and Temozolomide-Caused Lymphopenia
Status: COMPLETED
Conditions: Malignant Neoplasms Brain
Interventions: BIOLOGICAL: RNA-loaded dendritic cell vaccine|DRUG: basiliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irinotecan/Cisplatin, Potentially Curative Surgery With or Without Floxuridine, Followed by Capecitabine for Stomach and Gastro-esophageal Junction (GEJ) Cancers
Status: TERMINATED
Conditions: Gastric Cancer|Gastric Adenocarcinoma|Esophageal Cancer
Interventions: DRUG: Irinotecan|DRUG: Cisplatin|PROCEDURE: Surgery|DRUG: Floxuridine|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Differential Efficacy of Supportive and Interpretative Psychodynamic Techniques for Dependent and Self-critical Depressive Patients
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: OTHER: psychodynamic techniques.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Gut Microbiota Mediated Health Outcomes of Whole Wheat and Its Major Bioactive Components
Status: ACTIVE_NOT_RECRUITING
Conditions: PreDiabetes|Dysbiosis|Endotoxemia|Inflammation
Interventions: OTHER: Whole Wheat Bread|OTHER: White Bread (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Preoperative Tamsulosin to Prevent Postoperative Urinary Retention After Surgery For Pelvic Floor Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Urinary Retention
Interventions: DRUG: Tamsulosin 0.4Mg Capsule|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of a Bilateral TAP Block and Preperitoneal Instillation of Local Anesthetic for a Total Extraperitoneal (TEP) Repair
Status: COMPLETED
Conditions: Bilateral Inguinal Hernia Repair
Interventions: PROCEDURE: Transversus abdominis plane block (TAP BLOCK)|PROCEDURE: Instillation of surgical site with local anesthetic.|PROCEDURE: Opioid IV medications (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An ED-based RCT of Lethal Means Counseling for Parents of At-Risk Youth
Status: COMPLETED
Conditions: Suicidal and Self-injurious Behavior
Interventions: BEHAVIORAL: Safety Study Lethal Means Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Oral Rehydration Solution With Zinc and Prebiotics in Acute Diarrhea
Status: COMPLETED
Conditions: Diarrhea
Interventions: DIETARY_SUPPLEMENT: hypotonic oral rehydration solution|DIETARY_SUPPLEMENT: Hypotonic oral rehydration solution with Zn and prebiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Individually Tailored Digital Service to Promote Healthy and Sustainable Behaviors and Well-being
Status: NOT_YET_RECRUITING
Conditions: Well-being
Interventions: BEHAVIORAL: LongLife Active- Basic|BEHAVIORAL: LongLife Active- Standard|BEHAVIORAL: LongLife Active- Premium
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Staphylococcus Aureus Decolonization Study
Status: COMPLETED
Conditions: Staphylococcal Skin Infections|Abscesses|Furunculosis|Staphylococcus Aureus|MRSA Infection
Interventions: DRUG: 2% Mupirocin Ointment|DRUG: 4% Chlorhexidine liquid soap|BEHAVIORAL: Hygiene protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasonographic Evaluation of the Connective Tissue Grafts Obtained With Two Different Methods in Root Coverage
Status: COMPLETED
Conditions: Gingival Recession, Localized
Interventions: PROCEDURE: subepithelial connective tissue graft|PROCEDURE: de- epithelize gingival graft|DIAGNOSTIC_TEST: ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Premedication to Reduce Discomfort With Screening Mammography
Status: COMPLETED
Conditions: Breast Pain
Interventions: DRUG: 1000 mg acetaminophen|DRUG: 800 mg ibuprofen|DRUG: 1 oz 4% lidocaine gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of Bimatoprost in the Treatment of Primary Open Angle Glaucoma and Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: Bimatoprost 0.03%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Progesterone Versus Vaginal Progesterone Gel for Luteal Phase Support in Patients Undergoing In-Vitro Fertilization (IVF)
Status: COMPLETED
Conditions: In Vitro Fertilization
Interventions: DRUG: Progesterone|DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing MitoQ on Lower Urinary Tract Symptoms in Older Women With Metabolic Syndrome
Status: RECRUITING
Conditions: Lower Urinary Tract Symptoms|Overactive Bladder Syndrome
Interventions: DRUG: MitoQ (mitoquinol mesylate)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real-World Registry Assessing the Clinical Use of the Lutonix 035 Drug Coated Balloon Catheter
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Peripheral Vascular Diseases|Arterial Occlusive Diseases
Interventions: DEVICE: PTA (Lutonix® 035 DCB Catheter)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperspectral Retinal Observations for the Cross-sectional Detection of Alzheimer's Disease
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease, Early Onset|Cognitive Impairment|Cognitive Decline
Interventions: PROCEDURE: non-invasive hyperspectral retinoscopy|PROCEDURE: blood sample|DIAGNOSTIC_TEST: Test of cognitive ability on tablet computer with CoGNIT software
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Plyometric and Strength Training of Quadriceps and Hamstrings in Football Players
Status: COMPLETED
Conditions: Football Players
Interventions: OTHER: plyometric exercises|OTHER: strenghtening of quadriceps and hamstring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuropsychological and Neurophysiological Effects of Cognitive Stimulation in Patients With Alzheimer's Disease and Mild Cognitive Impairment
Status: UNKNOWN
Conditions: Alzheimer Disease
Interventions: OTHER: Cognitive Stimulation (CS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Ocular Safety After Repeated Instillations of T1225 1% or 1.5% Eye Drops in Healthy Volunteers
Status: COMPLETED
Conditions: Eye Infections, Bacterial
Interventions: DRUG: Azithromycin (T1225)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Role of Multidetector Computerized Tomography (MDCT) in Diagnosis of Non Traumatic Acute Abdomen in Pediatric Age Group.
Status: UNKNOWN
Conditions: Acute Abdomen in Children
Interventions: DEVICE: Multidetector Computerized Tomography (MDCT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analysis of the Enteric Nervous System Using Colonic Biopsies
Status: COMPLETED
Conditions: Parkinson's Disease|Multiple System Atrophy|Progressive Supranuclear Palsy
Interventions: PROCEDURE: colonoscopy or rectosigmoidoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Adherence to Guidelines for Antibiotic Use in Respiratory Infections at Hospitals
Status: COMPLETED
Conditions: Pneumonia|Chronic Bronchitis|COPD
Interventions: BEHAVIORAL: Professional education|BEHAVIORAL: Implementation of a Critical Care Pathway|BEHAVIORAL: Professional audit and feedback|BEHAVIORAL: Process analysis and redesign
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: ECT
Clinical trial: Stellate Ganglion Blockade in Post-Menopausal Women
Status: SUSPENDED
Conditions: Hot Flashes|Hot Flushes|Vasomotor Symptoms
Interventions: DRUG: Stellate Ganglion Block Injection with Bupivicaine|DRUG: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: P20 Extending Sleep to Reverse Metabolic Syndrome in Middle-Aged Adults: Acceptability and Feasibility of a Sleep Intervention
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: BEHAVIORAL: Sleep Intervention|BEHAVIORAL: Week 2 Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER