pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Diagnostic Efficacy and Prognostic Value of 18F-FDG PET/CT (MR) in Pediatric Solid Blastoma
Status: COMPLETED
Conditions: 18F-FDG|Neuroblastoma|Hepatoblastoma|Wilms Tumor
Interventions: OTHER: Telephone follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Analgesic Effectiveness of Intravenous Ketamine and Fentanyl for Spinal Anesthesia is Sitting Position in Patients With Proximal Femur Fracture
Status: UNKNOWN
Conditions: Fracture of Proximal End of Femur
Interventions: DRUG: Ketamine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Cleviprex in Ventriculostomy Patients Requiring IV Antihypertensive Therapy
Status: WITHDRAWN
Conditions: Hypertension|Intracranial Hemorrhage|Subarachnoid Hemorrhage
Interventions: DRUG: Clevidipine butyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of VR Educational Program on Empathy and Attitudes Toward Dementia in Caregivers
Status: NOT_YET_RECRUITING
Conditions: Dementia|Caregiver Burden
Interventions: OTHER: The virtual reality educational modules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Stress-Busting Program for Caregivers of Patients With Neruological Diseases
Status: COMPLETED
Conditions: Psychological Adaptation|Parkinson's Disease|Neurological Disorders
Interventions: BEHAVIORAL: Stress Busting Program for family caregivers
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Prevention of Emotional Disorders in Women Undergoing Fertility Treatments
Status: NOT_YET_RECRUITING
Conditions: Infertility|Emotional Disorder|Anxiety Depression
Interventions: BEHAVIORAL: Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Sımulatıon Used in Vagınal Chıldbırth on Malpractıce Tendency And Perceptıons of Care Behavıors
Status: COMPLETED
Conditions: Behavior|Perceptions
Interventions: BEHAVIORAL: Simulation-based training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Use of Injectable-platelet-rich-fibrin (I-PRF) to Thicken Gingival Phenotype
Status: COMPLETED
Conditions: Periodontoclasia|Gingiva; Injury|Condition|Blood Clot|Gingiva Disorder
Interventions: OTHER: I-PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of the Anti-Cancer Drug Talazoparib to the Combination of Carboplatin and Paclitaxel for the Treatment of Advanced Cancer
Status: COMPLETED
Conditions: Advanced Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm|Unresectable Malignant Solid Neoplasm
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Talazoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Clinical Activity of Curaleish in the Topical Treatment of Cutaneous Leishmaniasis.
Status: WITHDRAWN
Conditions: Leishmaniasis, Cutaneous
Interventions: DRUG: Experimental topical (Curaleish Topical)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of Oral CP-690,550 As A Maintenance Therapy For Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Placebo|DRUG: CP690,550|DRUG: CP-690,550
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: (PGA) for Platinum-resistant/Refractory, Paclitaxel-Pretreated Recurrent Ovarian and Peritoneal Carcinoma
Status: TERMINATED
Conditions: Ovarian Carcinoma|Fallopian Tube Carcinoma|Peritoneal Carcinoma
Interventions: DRUG: Gemcitabine|DRUG: Bevacizumab|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Optimizing a mHealth Physical Activity Intervention With Mindful Awareness Lessons in Breast Cancer Survivors
Status: RECRUITING
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Core Intervention|BEHAVIORAL: E-Coach|BEHAVIORAL: Buddy|BEHAVIORAL: General Mindfulness Training|BEHAVIORAL: MVPA-Specific Mindfulness Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Incentives to Promote Smoking Cessation in Low SES Women
Status: TERMINATED
Conditions: Nicotine Dependence
Interventions: BEHAVIORAL: Brief Motivational Intervention|BEHAVIORAL: Contingency Management|BEHAVIORAL: Non-Contingent Reinforcement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating the Efficacy of Annual CHTC Retesting Among Male Couples at High Risk of HIV Infection
Status: ENROLLING_BY_INVITATION
Conditions: HIV Infections
Interventions: BEHAVIORAL: Couples HIV testing and counseling|BEHAVIORAL: Individual HIV testing and counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Examining Safety, Efficacy and Feasibility of Preoperative Propranolol in Patients With PDAC.
Status: RECRUITING
Conditions: Pancreatic Cancer|Surgery
Interventions: DRUG: Propranolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LS-PersAFone: Pulsed Field Ablation for Long-Standing Persistent Atrial Fibrillation
Status: RECRUITING
Conditions: Long-standing Persistent AF
Interventions: DEVICE: Farawave PFA catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: nSTRIDE APS Versus Hyaluronic Acid for Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: nSTRIDE APS|DEVICE: Synvisc-One
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tecnis ZLB00 & Symfony Intraocular Lens Combination Outcomes
Status: COMPLETED
Conditions: Cataract Bilateral|Presbyopia
Interventions: DEVICE: Tecnis ZLB00 & Symfony IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Sacituzumab Govitecan Combinations in First-line Treatment of Participants With Advanced or Metastatic Non-Small-Cell Lung Cancer (NSCLC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Sacituzumab Govitecan-hziy (SG)|DRUG: Pembrolizumab|DRUG: Carboplatin|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Oral Premalignant Lesions With 5-ALA PDT
Status: COMPLETED
Conditions: Leukoplakia|Erythroplakia
Interventions: DEVICE: PDL-585, ScleroPLUS laser|DRUG: 5-Aminolevulinic Acid (Levulan KerastickTM)|PROCEDURE: Fluorescence Diagnosis Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study With SCB-313 (Recombinant Human TRAIL-Trimer Fusion Protein) for Treatment of Peritoneal Malignancies
Status: COMPLETED
Conditions: Peritoneal Malignancies
Interventions: DRUG: SCB-313
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Assess the Agent Paclitaxel Coated PTCA Balloon Catheter for the Treatment of Subjects With In-Stent Restenosis (ISR) - Long Lesion Cohort
Status: NOT_YET_RECRUITING
Conditions: In-Stent Restenosis
Interventions: DEVICE: AGENT DCB 40 mm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Endoscopic Lumbar Discectomy Add by Annuloplasty and Nucleoplasty
Status: NOT_YET_RECRUITING
Conditions: Lumbar Disc Herniation
Interventions: PROCEDURE: PELDAN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Follow-up Study in Subjects With Silicone Gel-filled Breast Implants as Compared Both to Saline-filled Breast Implants and to National Norms
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Implant
Interventions: OTHER: NBIR - US National Breast Implant Registry|DEVICE: 410 Arm|DEVICE: BIFs - Breast Implant Follow-Up Study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of SERT Inhibition on the Subjective Response to Psilocybin in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Escitalopram|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Swipe Out Stroke (SOS): Feasibility of Using a Consumer Based Electronic Application to Improve Compliance With Weight Loss in Obese Minority Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Mobile Application|BEHAVIORAL: Food Journal|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Adult Angiosarcoma|Adult Desmoplastic Small Round Cell Tumor|Adult Epithelioid Sarcoma|Adult Extraskeletal Myxoid Chondrosarcoma|Adult Extraskeletal Osteosarcoma|Adult Fibrosarcoma|Adult Leiomyosarcoma|Adult Liposarcoma|Adult Malignant Mesenchymoma|Adult Malignant Peripheral Nerve Sheath Tumor|Adult Rhabdomyosarcoma|Adult Synovial Sarcoma|Adult Undifferentiated High Grade Pleomorphic Sarcoma of Bone|Childhood Angiosarcoma|Childhood Desmoplastic Small Round Cell Tumor|Childhood Epithelioid Sarcoma|Childhood Fibrosarcoma|Childhood Leiomyosarcoma|Childhood Liposarcoma|Childhood Malignant Mesenchymoma|Childhood Malignant Peripheral Nerve Sheath Tumor|Childhood Pleomorphic Rhabdomyosarcoma|Childhood Rhabdomyosarcoma With Mixed Embryonal and Alveolar Features|Childhood Synovial Sarcoma|Dermatofibrosarcoma Protuberans|Malignant Adult Hemangiopericytoma|Malignant Childhood Hemangiopericytoma|Metastatic Childhood Soft Tissue Sarcoma|Previously Treated Childhood Rhabdomyosarcoma|Recurrent Adult Soft Tissue Sarcoma|Recurrent Childhood Rhabdomyosarcoma|Recurrent Childhood Soft Tissue Sarcoma|Stage III Adult Soft Tissue Sarcoma|Stage IV Adult Soft Tissue Sarcoma|Untreated Childhood Rhabdomyosarcoma
Interventions: BIOLOGICAL: Cixutumumab|DRUG: Doxorubicin Hydrochloride|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine Iatrogenic Hyperinsulinemia's Contribution to Insulin Resistance and Endothelial Dysfunction in Type 1 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: OTHER: Standard Carb Diet|OTHER: Low Carb Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Of The Pharmacokinetics Of Antithrombin III In Neonates And Infants Undergoing CPB And ECMO Support
Status: COMPLETED
Conditions: Extracorporeal Membrane Oxygenation Complication|Cardiopulmonary Bypass
Interventions: DRUG: Antithrombin III
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Endoscopic Imaging Methods for the Evaluation of Blood Vessels in Gastrointestinal Cancers
Status: UNKNOWN
Conditions: Gastric Cancer|Colorectal Cancer|Gastrointestinal Neoplasms
Interventions: PROCEDURE: Magnification endoscopy with narrow band imaging|DEVICE: Probe based confocal laser endomicroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of AK120 (IL-4Rα) in Healthy Subjects and Subjects With Moderate- to- Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: AK120 or placebo- Part 1- Cohort 1|DRUG: AK120 or placebo- Part 1- Cohort 2|DRUG: AK120 or placebo- Part 1- Cohort 3|DRUG: AK120 or placebo- Part 1- Cohort 4|DRUG: AK120 or placebo- Part 1- Cohort 5|DRUG: AK120 or placebo- Part 2- Cohort 1|DRUG: AK120 or placebo- Part 2- Cohort 2|DRUG: AK120 or placebo- Part 2- Cohort 3|DRUG: AK120 or placebo- Part 2- Cohort 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: An Efficacy and Safety Study of Risperidone Long-Acting Microspheres in Participants With Schizophrenia, Schizophreniform or Schizoaffective Disorders
Status: COMPLETED
Conditions: Schizophrenia|Schizophreniform Disorder|Schizoaffective Disorder
Interventions: DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transplacental Transmission of COVID-19
Status: TERMINATED
Conditions: SARS-COV-2 Infection
Interventions: OTHER: Samples concern SARS-COV-2 + pregnant women at the time of childbirth|OTHER: Samples concern newborns of SARS-COV-2 + mothers at birth
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Dose Escalation Trial of Stereotactic Body Radiation Therapy (SBRT) in Combination With GC4419 in Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer|Stereotactic Body Radiation Therapy
Interventions: DRUG: GC4419|DRUG: Placebo|RADIATION: Stereotactic Radiation Therapy (SBRT) 50 Gy|RADIATION: Stereotactic Radiation Therapy (SBRT) 55 Gy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Avoid With Locoregional Analgesia Persistant Postoperative Pain In Children
Status: RECRUITING
Conditions: Persistent Postoperative Pain
Interventions: DRUG: Carbocaine|DRUG: Profofol and/or Suxaméthonium and/or Sévoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Femtosecond Laser-assisted Arcuate Incisions Versus Manual Arcuate Incisions Outcomes
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: femtosecond laser system arcuate corneal incision|OTHER: Manual LRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Volasertib Plus Induction Chemotherapy for Acute Myeloid Leukemia
Status: WITHDRAWN
Conditions: Leukemia, Myeloid, Acute|Leukemia, Monocytic, Acute|Leukemia, Myelomonocytic, Acute|Leukemia, Erythroblastic, Acute|Leukemia, Megakaryoblastic, Acute
Interventions: DRUG: Volasertib|DRUG: Idarubicin|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About the Study Medicine (Maplirpacept) in People With Advanced Non-Hodgkin Lymphoma or Multiple Myeloma in China
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Hodgkin Lymphoma|Multiple Myeloma
Interventions: DRUG: Maplirpacept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Versus Delayed Treatment of Unilateral Neglect After Stroke
Status: COMPLETED
Conditions: Spatial Neglect After Stroke
Interventions: PROCEDURE: Prism adaptation with optical shift of 10 degrees.|PROCEDURE: Prism adaptation optical shift of 0 degrees.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Magnetic Resonance Imaging (MRI) vs Molecular Breast Imaging (Tc-MBI) in Breast Cancer Patients
Status: TERMINATED
Conditions: Breast Cancer
Interventions: OTHER: Sestamibi (Tc-MBI) scan of the breast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Adrenal Cortical Function and Vitamin A Deficiency in Sepsis
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: Solumedrol 20mg|DRUG: Vitamin A 100,000 IU|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin Injection in Hypercontractile Esophagus
Status: COMPLETED
Conditions: Nutcracker Oesophagus
Interventions: DRUG: Esophageal endoscopic injection of botulinum toxin|OTHER: No injection of botulinum toxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Macroscopic on Site Evaluation (MOLSE) vs Standard Specimen Acquisition of Solid Lesions During EUS-FNB
Status: UNKNOWN
Conditions: Endoscopic Ultrasonography With Tissue Acquisition
Interventions: OTHER: MOSE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Analgesic Efficacy of Us Guided Fascia Iliaca Block Versus Caudal Block in Pediatric Graft Surgeries
Status: NOT_YET_RECRUITING
Conditions: Surgery
Interventions: DRUG: Fascia iliaca block|DRUG: Caudal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Verification of Alternative Do-it-yourself Equipment Respirators for the COVID-19 Personal Protective Equipment (PPE)
Status: UNKNOWN
Conditions: COVID
Interventions: DEVICE: FFP2|DEVICE: Facial mask|DEVICE: MFS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Personalized Therapy of Patients Suffering From Rare Genodermatoses
Status: RECRUITING
Conditions: Rare Diseases
Interventions: OTHER: If a targetable cytokine is increased in the lesional skin of a patient, this patient is treated with the respective antibody therapy (off-label use of approved drug).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Postoperative Chemoradiation in Patients With Node-positive Esophageal Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Esophageal Neoplasms
Interventions: DRUG: Paclitaxel|DRUG: Cisplatin|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Examination of the Impact of a Dynamic Flexion Orthosis (Dynaflex®Ottobock) or of a Back Bandage (Lumbo Sensa®Ottobock) on the Voluntary Activation of the Back Muscles in Patients With Specific Back Pain"
Status: UNKNOWN
Conditions: Back Pain
Interventions: DEVICE: Lumbo Sensa® bandage|DEVICE: Dynaflex® flexion orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-TRBC1 CAR-T Cell Therapy in Patients With TRBC1 Positive T Cell Malignancies
Status: SUSPENDED
Conditions: Peripheral T Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Anaplastic Lymphoma|Acute T Cell Leukemia|T-lymphoblastic Lymphoma
Interventions: DRUG: anti-TRBC1 CAR-T cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Hepatic Impairment on the Single Dose Pharmacokinetics (PK) of Intravenous TAK-954
Status: COMPLETED
Conditions: Hepatic Impairment|Healthy Volunteers
Interventions: DRUG: TAK-954
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Atrial Fibrillation (AF) and Electrocardiogram (EKG) Interpretation Project ECHO
Status: ENROLLING_BY_INVITATION
Conditions: Atrial Fibrillation
Interventions: OTHER: AF and EKG Interpretation Project ECHO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efavirenz to Dolutegravir Switch in Patients With CNS Toxicity
Status: UNKNOWN
Conditions: HIV
Interventions: DRUG: Dolutegravir, efavirenz, efavirenz/emtricitabine/tenofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validity of Using Connected Soles In Measuring Steps Number In the Older Subject, Hospitalized in Follow-up and Rehabilitative Care and Achieve Its Rehabilitation Objectives
Status: RECRUITING
Conditions: Patient Recovering Maximum Walking Capacity, Over 10 Meter
Interventions: DEVICE: Feetme Connected Soles
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effect of Rapeseed Oil and Sunflower Oil
Status: UNKNOWN
Conditions: Familial Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: rapeseed oil|DIETARY_SUPPLEMENT: sunflower oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Focused and Radial Shock-Wave Therapies in Hip Osteoarthritis.
Status: COMPLETED
Conditions: Hip Osteoarthritis
Interventions: DEVICE: Extracorporeal Shock Wave Therapy (ESWT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S0509 - AZD2171 in Treating Patients With Malignant Pleural Mesothelioma That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Advanced Malignant Mesothelioma|Epithelial Mesothelioma|Recurrent Malignant Mesothelioma|Sarcomatous Mesothelioma
Interventions: DRUG: cediranib maleate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Investigate the Pharmacological Effects, Drug Blood Levels and Safety of an Intrauterine System Releasing the Study Drug BAY1007626 in Comparison to Mirena and Jaydess in Healthy Young Women Treated for 90 Days to Determine the Drug Dose for Further Development
Status: TERMINATED
Conditions: Contraception
Interventions: DRUG: BAY1007626|DRUG: Jaydess|DRUG: Mirena
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Gender-Sex Hormone Interface With Craving & Stress-Related Changes in Smoking
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: Oxytocin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin as a Potential Adjunct to Misoprostol for Termination of Pregnancy
Status: ACTIVE_NOT_RECRUITING
Conditions: Abortion Early
Interventions: DRUG: Atorvastatin|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Liver and Fat Regulation in Overweight Adolescent Girls
Status: COMPLETED
Conditions: Hepatic Steatosis|Polycystic Ovarian Syndrome|Obesity
Interventions: DRUG: Byetta 5Mcg Pen Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Two Doses of SPD476 (Mesalazine) 2.4g and 4.8g Once Daily, With Reference to Asacol 0.8g Three Times Daily in Subjects With Acute, Mild to Moderate Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: SPD476 is a polymeric matrix formulation that displays both delayed- and extended-release of mesalazine|DRUG: Mesalazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Chemotherapy Protocols Combined With Intensity Modulated Radiation Therapy in Patients With Locally Advanced Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Drug-Related Side Effects and Adverse Reactions
Interventions: DRUG: Cisplatin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring the Acceptability and Efficacy of a Transdiagnostic Treatment for Misophonia
Status: COMPLETED
Conditions: Misophonia
Interventions: BEHAVIORAL: Unified Protocol for Transdiagnostic Treatment of Emotional Disorders|BEHAVIORAL: Revised Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1 Monoclonal Antibody Plus Apatinib Combined With SBRT in HCC With PVTT
Status: UNKNOWN
Conditions: HCC
Interventions: DRUG: Terepril monoclonal antibody; Apatinib|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-inflammatory Effect of Pre-operative Stimulation of the Cholinergic Anti-Inflammatory Pathway
Status: RECRUITING
Conditions: Postoperative Ileus
Interventions: PROCEDURE: Vagus stimulation|PROCEDURE: Sham stimulation|DRUG: Prucalopride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adaptive Symptom Care Using Fish-Based Nutritional Directives Post Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Fatigue|Depression|Pain|Sleep Disturbance|Stress|Survivorship|Breast Cancer|Dietary Habits
Interventions: BEHAVIORAL: Personalized Meal Plan|BEHAVIORAL: Dietary Omega-3LC intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Role of GABA and Neurosteroids in Premenstrual Dysphoric Disorder
Status: COMPLETED
Conditions: Premenstrual Dysphoric Disorder|Premenstrual Syndrome
Interventions: DRUG: fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eosinophil Induced Remodelling in Asthma
Status: COMPLETED
Conditions: Allergic Asthma|Airway Remodelling
Interventions: PROCEDURE: Bronchial challenge with allergen|OTHER: Co-culture formation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of Change in CYP3A Activity by Route of Administration Using Metabolic Markers in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Midazolam|DRUG: Clarithromycin|DIETARY_SUPPLEMENT: Grapefruit juice
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prevention And Treatment Of Chemotherapy-Induced Peripheral Neuropathy In Subjects With Advanced Colorectal Cancer
Status: TERMINATED
Conditions: Chemotherapy-Induced Peripheral Neuropathy
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: University Hospital of Ioannina COVID-19 (Coronavirus Disease 2019) Registry
Status: RECRUITING
Conditions: COVID-19 (Coronavirus Disease 2019)|COVID-19 Pandemic|COVID-19 Pneumonia|COVID-19 Respiratory Infection|COVID-19 Acute Respiratory Distress Syndrome|COVID-19-Associated Thromboembolism|COVID-19-Associated Pneumonia|COVID 19 Associated Coagulopathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Subtenon Block Combined With General Anesthesia for Vitreoretinal Surgery
Status: COMPLETED
Conditions: Subtenon Anesthesia
Interventions: DRUG: 2% lidocaine and 0.5% bupivacaine|DRUG: Sham subtenon block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ciclosporin to Reduce Reperfusion Injury in Primary PCI
Status: COMPLETED
Conditions: Myocardial Reperfusion Injury
Interventions: DRUG: Ciclosporin|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate and Short Term Outcomes for Using Drug Coated Balloons in Treating Coronary Bifurcation Lesions
Status: RECRUITING
Conditions: Ischemia; Heart|Stents
Interventions: DIAGNOSTIC_TEST: Coronary angiography plus percutenous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Birinapant and Intensity Modulated Re-Irradiation Therapy in Treating Patients With Locally Recurrent Head and Neck Squamous Cell Carcinoma
Status: TERMINATED
Conditions: Locally Recurrent Head and Neck Squamous Cell Carcinoma|Nasopharyngeal Squamous Cell Carcinoma|Sinonasal Squamous Cell Carcinoma
Interventions: DRUG: Birinapant|RADIATION: Intensity-Modulated Radiation Therapy|PROCEDURE: Tumor Biopsy|DIAGNOSTIC_TEST: PET Scan|DIAGNOSTIC_TEST: CT Scan|DIAGNOSTIC_TEST: MRI Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Dose Response of Korean White Ginseng in Metabolic Syndrome or Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: 1 gram of White Korean Ginseng|DIETARY_SUPPLEMENT: 3 grams of White Korean Ginseng|DIETARY_SUPPLEMENT: 6 grams of White Korean Ginseng|DIETARY_SUPPLEMENT: 3 grams of Wheat Bran Control|DIETARY_SUPPLEMENT: 500mg of Korean Red Ginseng
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FLO2 for Recovery After SCI
Status: COMPLETED
Conditions: Spinal Cord Injury (SCI)
Interventions: OTHER: Daily AIH Block|OTHER: Sham dAIH Block|OTHER: Respiratory Strength Training Block|OTHER: AIH + Strength Training Block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tuned Versus Untuned Ankle-foot Orthoses in Children and Adolescents With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: barefoot|OTHER: shoes only|OTHER: untuned AFO with shoes|OTHER: tuned AFO with shoes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IIb Study of PRO045 in Subjects With Duchenne Muscular Dystrophy
Status: TERMINATED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: PRO045, 0.15 mg/kg/week|DRUG: PRO045, 1.0 mg/kg/week|DRUG: PRO045, 3.0 mg/kg/week|DRUG: PRO045, 6.0 mg/kg/week|DRUG: PRO045, 9.0 mg/kg/week|DRUG: PRO045, selected dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Epidemiology of NAFLD in Children and Adolescents
Status: UNKNOWN
Conditions: Non-Alcoholic Fatty Liver Disease|Childhood Obesity
Interventions: DIAGNOSTIC_TEST: Vibration-Controlled Transient Elastography (VCTE) with Controlled Attenuation Parameter (CAP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anti-CD3 x Anti-Erbitux® Armed Activated T Cells (Phase Ib) for Gastrointestinal (GI Cancer)
Status: COMPLETED
Conditions: Colorectal Cancer|Cancer of Pancreas|Pancreatic Neoplasm|Malignant Neoplasm of Large Intestine|Malignant Tumor of Colon|Colon Carcinoma|Cancer of Colon|Pancreatic Cancer
Interventions: DRUG: FOLFOX6|BIOLOGICAL: EGFRBi armed ATC Infusions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glyburide vs Placebo as Prophylaxis Against Cerebral Edema in Patients Receiving Radiosurgery for Brain Metastases (RAD 1502/UAB 1593)
Status: TERMINATED
Conditions: Cerebral Edema|Brain Metastases
Interventions: DRUG: Glyburide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PPI Infusion Versus Oral Acid Pump Inhibitors for Bleeding Peptic Ulcers
Status: RECRUITING
Conditions: Upper GI Bleeding|Proton Pump Inhibitors
Interventions: DRUG: Vonoprazan|DRUG: esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency of XELOX Neoadjuvant Chemotherapy in Gastric Cancer
Status: TERMINATED
Conditions: Gastric Cancer
Interventions: DRUG: Capecitabine|DRUG: Oxaliplatin|PROCEDURE: D2 resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurobehavioral Mechanisms of Choice in Opioid Use Disorder
Status: RECRUITING
Conditions: Opioid Use Disorder
Interventions: DRUG: Oxycodone|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low Intensity Focused Ultrasound for Tobacco Use Disorder: High Resolution Targeting of the Human Insula
Status: RECRUITING
Conditions: Tobacco Use Disorder
Interventions: DEVICE: low intensity focused ultrasound (LIFU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cadonilimab Monotherapy as Neoadjuvant Therapy for Resectable II-IIIA Squamous Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Cadonilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gleevec Idiopathic Pulmonary Fibrosis (IPF) Study
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis|Lung Disease|Pulmonary Fibrosis
Interventions: DRUG: Imatinib Mesylate (Gleevec)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: ECT
Clinical trial: Analgesic Efficacy of US-Guided Interscalene Block Versus Supraclavicular Block for Ambulatory Arthroscopic Rotator Cuff Repair
Status: COMPLETED
Conditions: Shoulder Lesions
Interventions: PROCEDURE: arthroscopic shoulder surgery of rotary cuff (ISB)|PROCEDURE: arthroscopic shoulder surgery of rotary cuff (CSB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of GM-CSF Treatment in Recurrent Implantation Failure
Status: UNKNOWN
Conditions: Women With Recurrent Implantation Failure in IVF
Interventions: DRUG: GM-CSF group|DRUG: CONTROL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: JOTROL PK, Safety, and Food Effect Assessment
Status: COMPLETED
Conditions: Pharmacokinetics|Safety|Food-drug Interaction
Interventions: DRUG: 200 mg resveratrol as JOTROL|DRUG: 500 mg resveratrol as JOTROL|DRUG: 700 mg resveratrol as JOTROL|DRUG: 500 mg resveratrol as JOTROL administered to assess influence of food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Imvamune Vaccine for the Treatment of Non-melanoma Skin Cancer
Status: TERMINATED
Conditions: Non-melanoma Skin Cancer|Basal Cell Carcinoma|Squamous Cell Carcinoma
Interventions: BIOLOGICAL: Imvamune
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROACT: Can we Prevent Chemotherapy-related Heart Damage in Patients With Breast Cancer and Lymphoma?
Status: COMPLETED
Conditions: Breast Cancer|Non Hodgkin Lymphoma
Interventions: DRUG: Enalapril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Novel Breathing Behavior Modification Yoga Positioning Integrated Program on Weight Loss
Status: ACTIVE_NOT_RECRUITING
Conditions: Weight Loss|Metabolism
Interventions: OTHER: Deep breathing with Yoga positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Hypopressive Exercises on Postpartum Backache and Functional Disability
Status: NOT_YET_RECRUITING
Conditions: Low Back Pain
Interventions: COMBINATION_PRODUCT: Hypopressive Exercises and (heat therapy, medication, and progressive strength training)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of AIN457/Secukinumab in Patients With Rotator Cuff Tendinopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Tendinopathy
Interventions: DRUG: secukinumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Montelukast in Pediatric Allergic Asthma (0476-336)(COMPLETED)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: montelukast sodium|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety, Efficacy and Tolerability Study of SEP-225289
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: SEP-225289|DRUG: SEP-225289|DRUG: Venlafaxine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Proteome-based Immunotherapy of Brain Metastases From Breast Cancer
Status: UNKNOWN
Conditions: Neoplasm Metastasis
Interventions: BIOLOGICAL: Dendritic vaccine, allogeneic hematopoietic stem cells, cytotoxic lymphocytes|BIOLOGICAL: Dendritic vaccine, autologous hematopoietic stem cells, cytotoxic lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy in Treating Patients With Progressive or Recurrent Malignant Brain Tumors
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: PROCEDURE: surgical procedure|RADIATION: brachytherapy|RADIATION: intraoperative radiation therapy|RADIATION: iodine I 125
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Ensuring Patients' Informed Access to Noninvasive Prenatal Testing
Status: COMPLETED
Conditions: Genetic Disease|Genetic Syndrome|Prenatal Disorder|Prenatal Maternal Abnormality|Pregnancy Complications
Interventions: BEHAVIORAL: NEST|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Tebipenem Trial in Children With Shigellosis
Status: RECRUITING
Conditions: Shigellosis
Interventions: DRUG: Tebipenem Pivoxil|DRUG: Azithromycin|DRUG: Ceftriaxon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation Of A New Medication (GW642444) In Asthmatic Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: GW642444|DRUG: Placebo|DRUG: salmeterol 50mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Consumption of Ferric Hydroxide Adipate on Urinary Phosphorus Excretion.
Status: COMPLETED
Conditions: Healthy|Chronic Kidney Diseases
Interventions: DRUG: Calcium acetate|DIETARY_SUPPLEMENT: Iron Hydroxide Adipate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Erythropoietin Usage in Renal Function After Kidney Transplantation, in Early Phase, in Contrast to Placebo Group
Status: UNKNOWN
Conditions: Transplantation, Kidney
Interventions: DRUG: Erythropoietin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Enhancers and Inhibitors on Absorption From Iron Supplements
Status: COMPLETED
Conditions: Iron-deficiency|Iron Deficiency Anemia
Interventions: OTHER: Reference|OTHER: Ascorbic acid (AA) 500 mg|OTHER: Ascorbic acid (AA) 80 mg|OTHER: Coffee|OTHER: Breakfast|OTHER: Afternoon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study Evaluating Antibody Persistence and Safety, Tolerability and Immunogenicity of a Booster Dose of Novartis rMenB±OMV NZ Vaccine in Healthy UK Children Who Previously Received Three Doses of the Same Vaccine
Status: COMPLETED
Conditions: Meningococcal Disease
Interventions: BIOLOGICAL: rMenB|BIOLOGICAL: rMenB+OMV NZ
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Psychosocial Intervention Plus Early Palliative Care in the Reduction of Depression of Advanced Cancer Patients
Status: TERMINATED
Conditions: Neoplasms
Interventions: BEHAVIORAL: Brief Psychosocial Intervention|OTHER: Early Palliative Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate EMB 001 in Subjects With Cocaine Use Disorder
Status: COMPLETED
Conditions: Cocaine Use Disorder
Interventions: DRUG: EMB-001|DRUG: EMB-001 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ablation Verses Anti-arrhythmic Therapy for Reducing All Hospital Episodes From Recurrent Atrial Fibrillation
Status: COMPLETED
Conditions: Heart Failure|Recurrent Atrial Fibrillation
Interventions: PROCEDURE: AVATAR-AF ablation|DRUG: Anti-Arrhythmic therapy|PROCEDURE: Conventional AF ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Programmed Intermittent Bolus Infusion of Thoracic Paravertebral Block for Hepatectomy
Status: COMPLETED
Conditions: Paravertebral Block|Hepatectomy|Analgesia|Postoperative Recovery
Interventions: PROCEDURE: Paravertebral block-ropivacaine|PROCEDURE: Paravertebral block-saline|DRUG: patient controlled analgesia with morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Benefit of Nebulized Bronchodilators at Home in Severe Chronic Obstructive Pulmonary Disease and Very Severe Steady State
Status: COMPLETED
Conditions: Severe Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Atrovent + Bricanyl or Atrovent + Ventoline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: A Clinical Effectiveness Study Examining the Efficacy and Safety of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Age-related Macular Degeneration|Neovascular Age-related Macular Degeneration|Wet Macular Degeneration
Interventions: BIOLOGICAL: bevacizumab|BIOLOGICAL: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIV Self-Testing Africa (STAR) Malawi: General Population
Status: COMPLETED
Conditions: HIV
Interventions: DEVICE: OraQuick ADVANCE HIV I/II test kits, packaged for self-use (manufactured in Thailand)|OTHER: Home-based initiation of ARVs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC