pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: ESPB Combined With Intercostal Nerve Block in VATs
Status: UNKNOWN
Conditions: Video Assisted Thoracoscopic Surgery
Interventions: PROCEDURE: ESPB and Intercostal nerve block|PROCEDURE: Intercostal nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Persistent Atrial Fibrillation Without the Evidence of Low-voltage Areas
Status: ACTIVE_NOT_RECRUITING
Conditions: Persistent Atrial Fibrillation|Catheter Ablation|Low Voltage Areas
Interventions: DEVICE: Catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Cuff Brachytherapy Followed by Chemotherapy in Patients With Endometrioid Cancer
Status: COMPLETED
Conditions: Endometrial Cancer|Papillary Serous|Clear Cell Endometrial Cancer
Interventions: RADIATION: Vaginal Cuff Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Daily Zinc Supplementation to Infants Born With Low Birth Weight on Death and Severe Disease
Status: COMPLETED
Conditions: Pneumonia|Diarrhea|Meningitis|Sepsis|Death
Interventions: DRUG: Oral zinc gluconate (5 mg elemental)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Safety and Efficacy of Levoketoconazole in the Treatment of Endogenous Cushing's Syndrome.
Status: COMPLETED
Conditions: Endogenous Cushing's Syndrome
Interventions: DRUG: Levoketoconazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Efficacy and Safety of LIV-GAMMA SN Inj.10% in Primary Immune Thrombocytopenia (ITP)
Status: COMPLETED
Conditions: Immune Thrombocytopenia
Interventions: BIOLOGICAL: LIV-GAMMA SN Inj.10%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of TPF as First-line Chemotherapy in Patients With Metastatic Esophageal Cancer.
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: Taxotere|DRUG: 5-FU|DRUG: Briplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Antidepressant Efficacy of a Combination Herbal Drug Preparation (NEURAPAS Balance)
Status: TERMINATED
Conditions: Depressive Disorder
Interventions: DRUG: Neurapas® balance (Herbal combination out of hypericum, valerian, passionflower)|DRUG: film-coated sugar-pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CBTI-CS: A Novel Cognitive-Behavioral Treatment for Insomnia in Cancer Survivors
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: CBTI-CS|BEHAVIORAL: Sleep Hygiene|BEHAVIORAL: CBTI-CS via Telehealth
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rheumatoid Arthritis and Treatment of Periodontitis: a Randomized Clinical Trial.
Status: COMPLETED
Conditions: Periodontitis|Arthritis, Rheumatoid
Interventions: PROCEDURE: Immediate non-surgical periodontal treatment and oral hygiene instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Post Intravitreal Injection Topical NSAID vs. Patching
Status: UNKNOWN
Conditions: Neovascular Age-related Macular Degeneration|Diabetic Macular Edema|Retinal Vein Occlusion
Interventions: DRUG: nepafenac 0.3% suspension (Ilevro; Alcon, Fort Worth, TX)|DRUG: Theratears tear drop, (Akron, Ann 111 Arbor, MI)|OTHER: patching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evolution of Total Energy Expenditure and Its Various Components in Active Rheumatoid Arthritis (RA)Treated With Anti-TNF Agents and Comparison With Healthy Subjects
Status: UNKNOWN
Conditions: Active Rheumatoid Arthritis
Interventions: BEHAVIORAL: Energy metabolism of patients suffering from RA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Open-Label Extension Treatment With Etanercept (TNFR:Fc) for Participating Patients in Etanercept (TNFR:Fc) Clinical Trial 016.0012
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Assessment of Graft Fibrosis After Living Donor Liver Transplantation
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DIAGNOSTIC_TEST: Fibro-α score = (1.35 (numeric constant) +AFP (IU ml-1) × 0.009584 + aspartate aminotransferase (AST)/alanine aminotransferase(ALT) × 0.243 - platelet count (×109 l-1) × 0.001624).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Chemotherapy in Treating Patients With Advanced Stomach, Gastroesophageal, or Esophageal Cancer
Status: COMPLETED
Conditions: Stomach Neoplasms|Esophageal Neoplasms
Interventions: DRUG: Irinotecan|DRUG: Trastuzumab|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Antioxidants in Unexplained Oligohydramnios,A Randomized Trial
Status: COMPLETED
Conditions: Oilgohydramnios
Interventions: DRUG: anti oxidant omega 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study In Healthy Subjects Of Single Doses of PF-05230901 Injected Under The Skin
Status: TERMINATED
Conditions: Cachexia
Interventions: DRUG: PF-05230901|DRUG: PF-05230901
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Detecting Absence Seizures Using Hyperventilation and Eye Movement Recordings
Status: RECRUITING
Conditions: Absence Epilepsy, Childhood|Absence Seizures|Absence Epilepsy|Epilepsy in Children|Staring|Seizures
Interventions: DEVICE: Eysz Hyperventilation Recorder
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Proof of Concept Trial of Vamorolone in Pediatric Ulcerative Colitis
Status: WITHDRAWN
Conditions: Pediatric Ulcerative Colitis
Interventions: DRUG: Vamorolone 4% suspension for oral dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Post-TIPS Hepatic Encephalopathy by Administration of Rifaximin and Lactulose
Status: UNKNOWN
Conditions: Hepatic Encephalopathy|Cirrhosis, Liver|Portal Hypertension|Liver Diseases|Pathological Processes
Interventions: DRUG: Rifaximin 550 milligram Oral Tablet [XIFAXAN]|DRUG: Placebo oral tablet|DRUG: Lactulose 667 milligram/milliliter Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pivotal IDE Study of the BRYAN(R) Cervical Disc Prosthesis in the Treatment of DDD Versus ACDF
Status: COMPLETED
Conditions: Radiculopathy|Myelopathy|Cervical Degenerative Disc Disease
Interventions: DEVICE: ATLANTIS™ Cervical Plate System and allograft|DEVICE: BRYAN Cervical Disc Prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics of BAL8728 After a Single Dose of Pyridinylmethyl-14C-Labeled Isavuconazonium Sulfate in Healthy Male Subjects
Status: COMPLETED
Conditions: Pharmacokinetics of 14C-labeled Isavuconazonium Sulfate|Healthy Subjects
Interventions: DRUG: Pyridinylmethyl-14C-labeled isavuconazonium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Preventing ICU Subsyndromal Delirium Conversion to Delirium With Haloperidol
Status: COMPLETED
Conditions: Subsyndromal Delirium
Interventions: DRUG: Haloperidol decanoate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin Infections
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: DRUG: IV Vancomycin plus IV Aztreonam|DRUG: Ceftaroline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proteomic Guided First-line Precision Treatment of Renal Clear Cell Carcinoma
Status: RECRUITING
Conditions: Kidney Cancer|Renal Cell Carcinoma|Renal Clear Cell Carcinoma
Interventions: DRUG: Anlotinib, Everolimus and Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First in Human Study in Healthy Volunteers of Antimicrobial Peptide PL-18 Vaginal Suppositories
Status: RECRUITING
Conditions: Colpomycosis|Bacterial Vaginosis|Mixede Vaginitis
Interventions: DRUG: Dose 1 to 5 of Antimicrobial Peptide PL-18 Vaginal Suppositories|DRUG: Placebo dose 1 to 5 of Antimicrobial Peptide PL-18 Vaginal Suppositories
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: STem cElls Mobilization in Acute Myocardial Infarction Outcome Trial
Status: TERMINATED
Conditions: Anterior Acute Myocardial Infarction|Left Ventricular Systolic Dysfunction
Interventions: DRUG: G-CSF administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimised MultiSite Pacing Vector Study
Status: UNKNOWN
Conditions: Heart Failure|Left Bundle-Branch Block|Systolic Dysfunction
Interventions: DEVICE: Optimised MultiSite Pacing|DEVICE: Standard biventricular pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous T Cells Targeting HPV16 HPV18 & Survivin in Patients With R/R HPV-related Oropharyngeal Cancers
Status: NOT_YET_RECRUITING
Conditions: Oropharyngeal Cancer|Human Papilloma Virus|Head and Neck Cancer|Head and Neck Squamous Cell Carcinoma|Oropharyngeal Squamous Cell Carcinoma|Oropharyngeal Cancer, Metastatic|Head and Neck Cancer Metastatic|HPV-Related Squamous Cell Carcinoma|HPV-Related Mucosal Head and Neck Squamous Cell Carcinoma|Relapsed Oropharyngeal SCC|Refractory Oropharyngeal Squamous Cell Carcinoma
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|BIOLOGICAL: NEXI-003 T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Intra-abdominal Ropivacaine 0.5% Spray on Postoperative Analgesia in Laparoscopic Surgery.
Status: UNKNOWN
Conditions: Pain, Acute
Interventions: DRUG: Ropivacaïne 0,5% for appendectomy or cholecystectomy surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Statin in Hip Fracture
Status: TERMINATED
Conditions: Hip Fracture
Interventions: DRUG: Rosuvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-level Antimicrobial Surface Coating for a Healthier Environment
Status: COMPLETED
Conditions: Hospital Acquired Infections
Interventions: COMBINATION_PRODUCT: Regular Patient privacy curtain|COMBINATION_PRODUCT: Antimicrobial Coated curtains
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: BIIB023 Long-Term Extension Study in Subjects With Lupus Nephritis
Status: TERMINATED
Conditions: Lupus Nephritis
Interventions: BIOLOGICAL: BIIB023|DRUG: mycophenolate mofetil|DRUG: oral corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Immunoglobulin Intravenous (Human) 10% (NewGam) in Primary Immune Thrombocytopenia
Status: COMPLETED
Conditions: Primary Thrombocytopenia
Interventions: DRUG: NewGam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Chemotherapy With Gemcitabine and Cisplatin Compared to Standard of Care After Curative Intent Resection of Biliary Tract Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cholangiocarcinoma|Gall Bladder Carcinoma
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tree Nuts Allergies: Does a Single Nut Allergy Necessitate the Dietary Eviction of Other Tree Nuts?
Status: COMPLETED
Conditions: Nut Allergy in Children
Interventions: OTHER: Oral food challenges to multiple nuts
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Web-Based Education on ERAS Protocols Applied in Gynecological and Obstetric Surgery
Status: NOT_YET_RECRUITING
Conditions: ERAS
Interventions: OTHER: Web-Based Training on ERAS Protocols Applied in Gynecological and Obstetric Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Fimasartan Alone or Combined With HCTZ in Mexican Patients With Essential Hypertension
Status: COMPLETED
Conditions: Hypertension, Essential
Interventions: DRUG: Fimasartan|DRUG: Fimasartan; Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuing the Conversation: Using Narrative Communication to Support Hypertension Self-management in African American Veterans
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: CTC Intervention|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Analysis of Vital, Facial and Muscular Responses Front to Music or Message in Coma, Vegetative State or Sedated Patients
Status: COMPLETED
Conditions: Consciousness Disorders|Communication|Intensive Care
Interventions: OTHER: Music and voice message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Green Coffee Extract Supplementation on Leptin, Ghrelin, Adiponectin,Anthropometric Measurements, Lipid Profile in Breast Cancer Survivors
Status: UNKNOWN
Conditions: Breast Cancer Survivors
Interventions: DIETARY_SUPPLEMENT: green coffee|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study to Evaluate ISV-305 Compared to Vehicle in Blepharitis Subjects
Status: COMPLETED
Conditions: Active, Symptomatic Blepharitis
Interventions: DRUG: ISV-305|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antigen-Lipid-Driven Monoclonal Gammopathies Targeting Epicardial Fat
Status: WITHDRAWN
Conditions: Monoclonal Gammopathies|Overweight|Obesity
Interventions: DRUG: Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Care as a Preventive Measure of VAP; Miswak Versus Chlorhexidine and Toothbrush.
Status: COMPLETED
Conditions: Ventilator Associated Pneumonia
Interventions: PROCEDURE: Oral care in mechanically ventilated patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of 0.5mg Dutasteride and 0.4mg Tamsulosin Combination Once Daily for Six Months for Benign Prostatic Hyperplasia
Status: TERMINATED
Conditions: Prostatic Hyperplasia
Interventions: DRUG: Dutasteride/Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a 4% Hydroquinone Cream for the Treatment of Melasma
Status: COMPLETED
Conditions: Facial Melasma
Interventions: DRUG: Hydroquinone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Care-based Facilitated Access to a Web Based Brief Intervention to Reduce Alcohol Consumption
Status: COMPLETED
Conditions: Hazardous Drinking
Interventions: BEHAVIORAL: Face-to-Face Brief Intervention|BEHAVIORAL: Online Brief Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxygen Extraction-guided Transfusion
Status: RECRUITING
Conditions: Blood Transfusion
Interventions: OTHER: Individualized red blood cell transfusion strategy|OTHER: European guidelines red blood cell transfusion strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Doxapram Therapy in Preterm Infants (DOXA Trial)
Status: RECRUITING
Conditions: Apnea of Prematurity|Respiratory Insufficiency
Interventions: DRUG: Doxapram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sitagliptin on Incretin Effect in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Placebo tablet|DRUG: Sitagliptin tablet|DRUG: Saline infusion|DRUG: Exendin(9-39) infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Annovera™ Drug-Drug Interaction Study
Status: COMPLETED
Conditions: Women|Contraception
Interventions: DRUG: Segesterone Acetate and Ethinyl Estradiol|DRUG: Rifampin|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Thoracic Manipulation Techniques to Improve Neck Pain in Dentistry Students
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Thoracic Spine Thrust in Seated Position|OTHER: Thoracic Spine Thrust in Supine Position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prehabilitation With Resistance-exercise Training for Breast Cancer Neoadjuvant Therapy
Status: NOT_YET_RECRUITING
Conditions: Prehabilitation|Breast Cancer|Postmenopause|Resistance Training
Interventions: OTHER: Prehabilitation with resistance-exercise training|OTHER: Usual care program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of PAD and TAD in Newly Diagnosed Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib,Pirarubicin,Dexamethasone|DRUG: Thalidomide,Pirarubicin,Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of Intra-Operative MRI-Based Guidance for Laser Ablation of Epidural Metastasis
Status: COMPLETED
Conditions: Spinal Tumor
Interventions: PROCEDURE: Magnetic Resonance Imaging (MRI)|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bioavailability of Vagantin® Coated Tablets Relative to an Oral Methantheline Bromide Solution
Status: COMPLETED
Conditions: Neurogenic Bladder
Interventions: PROCEDURE: blood sampling|DRUG: Vagantin®|DRUG: methantheline solution|PROCEDURE: Measurement of salivation|PROCEDURE: Measurement of accommodation|PROCEDURE: Pupillometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Alendronate to Prevent and Treat Osteoporosis in Cystic Fibrosis Patients
Status: COMPLETED
Conditions: Cystic Fibrosis|Osteoporosis|Bone Diseases, Metabolic
Interventions: DRUG: Alendronate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Automated Oxygen Administration -Rethinking Interventions Alleviating Dyspnea in Patients With COPD
Status: COMPLETED
Conditions: COPD|Hypoxia|Closed-Loop Communication|Dyspnea|Anxiety|Depression
Interventions: DEVICE: O2matic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of SeV-G(NP) HIV Vaccine Administered Intranasally and Ad35-GRIN HIV Vaccine Given Intramuscularly in Prime-Boost Regimens in HIV-Uninfected Volunteers
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: SeV-G(NP) (0.2mL, 2x10^7 CIU)|BIOLOGICAL: SeV-G(NP) (0.2mL, 2x10^8 CIU)|BIOLOGICAL: Ad35-GRIN (0.5mL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of HABIT-ILE on the Body Function and Structures of Children With Cerebral Palsy
Status: UNKNOWN
Conditions: Cerebral Palsy
Interventions: BEHAVIORAL: HABIT-ILE|BEHAVIORAL: Conventional intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Evaluating Bioequivalence of Test and Reference Vadadustat 450 MG and 150 MG Tablets and to Determine Food Effect on the 450 MG Tablet
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: vadadustat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GENetic Education Risk Assessment and TEsting Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Candidates for Hereditary Pancreatic Cancer Testing
Interventions: OTHER: Doxy.me genetic education +/- Color Genomics genetic education|OTHER: Color Genomics genetic education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: C1q/TNF-related Protein 9 (CTRP 9) Level in Preeclamptic Obese and Non-obese Pregnancies
Status: COMPLETED
Conditions: Pre-Eclampsia|Obesity; Endocrine
Interventions: DIAGNOSTIC_TEST: Blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of the TNF-alpha Inhibiton on Hemodynamic Parameters in Resistant Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: BIOLOGICAL: Infliximab|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-mode Stroke Rehabilitation System: Development and Validation of Clinical Efficacy
Status: COMPLETED
Conditions: Stroke|Cerebrovascular Disorders|Central Nervous System Diseases
Interventions: BEHAVIORAL: Digital Action Observation Therapy (Digital AOT)|BEHAVIORAL: Digital Mirror Therapy (Digital MT)|BEHAVIORAL: Conventional Occupational Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Dose-Ranging Clinical Trial of Topical Creams Containing API 31510 for the Treatment of Superficial Basal Cell Carcinoma
Status: COMPLETED
Conditions: Superficial Basal Cell Carcinoma
Interventions: DRUG: API 31510 3% Topical Cream|DRUG: API 31510 1.5% Topical Cream|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Balance Training by BBS on Gait Parameters and Balance in Patients With RLAS
Status: COMPLETED
Conditions: Ankle Sprains
Interventions: DEVICE: Biodex Balance System|OTHER: specific physical therapy exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Using Spectrally Encoded Confocal Microscopy (SECM) to Image the Esophagus
Status: ACTIVE_NOT_RECRUITING
Conditions: Eosinophilic Esophagitis
Interventions: DEVICE: SECM Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Performance of the Pantera Lux Balloon Versus the Orsiro Stent in Patients With In-stent Restenosis.
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Restenosis
Interventions: DEVICE: Percutaneous coronary intervention|DEVICE: Percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Effects of Lion's Breath Technique With Chest Percussion Therapy in Pneumonia Patients
Status: COMPLETED
Conditions: Pneumonia
Interventions: OTHER: Lion's Breath Technique|OTHER: Chest Percussion Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Volume Replacement With HES 130/0.4 Versus Ringer's Lactate (RL) Regarding Their Effects on Inflammatory Biomarkers (Cytokines and Matrix Metalloproteinases) Responses to Major Abdominal Surgery.
Status: COMPLETED
Conditions: Postoperative Inflammation
Interventions: OTHER: Ringer's Lactate|OTHER: HES 130/0.4 and Ringer's Lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: PH 1 Biomarker Study of Nivolumab and Ipilimumab and Nivolumab in Combination With Ipilimumab in Advanced Melanoma
Status: COMPLETED
Conditions: Advanced Melanoma|Metastatic Melanoma
Interventions: BIOLOGICAL: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Development of a Multifunctional Rehabilitation Device for Persons With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: Multifunctional RehabilitationDevice (MRD)|DEVICE: existing standard rehabilitation device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Upper Limb Biofeedback Rehabilitation System (RAPAELⓇ Smart Glove Digital Treatment System) Training for Stroke Recovery
Status: UNKNOWN
Conditions: Stroke|Cerebral Vascular Accident
Interventions: DEVICE: RAPAELⓇ Smart Glove digital treatment system|BEHAVIORAL: Additional occupational therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD) Study
Status: RECRUITING
Conditions: Alzheimer Disease, Early Onset|Mild Cognitive Impairment
Interventions: DRUG: Dasatinib + Quercetin|OTHER: Placebo Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PEEP Guided by Esophageal Balloon Measurement and Its Effect on Recruitment Maneuver
Status: UNKNOWN
Conditions: ARDS
Interventions: OTHER: PEEP guided by Esophageal pressure + Recruitment maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Injectable Anticoagulants on Research for a Circulating Lupus-type Anticoagulant
Status: COMPLETED
Conditions: Antiphospholipid Syndrome|Anticoagulant Drugs
Interventions: DIAGNOSTIC_TEST: Lupus anticoagulant testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Saline Flush to Reduce the Amount of Residual Air Inside a Stentgraft Delivery System
Status: COMPLETED
Conditions: Aortic Aneurysm|Aortic Aneurysm, Thoracic|Aortic Diseases|Aortic Arch Aneurysm|Stroke
Interventions: PROCEDURE: Increased saline flush volume
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A 6-week Study to Evaluate the Safety and Efficacy of Methylphenidate HCl ERCT in 4-5 Year Old Children With ADHD
Status: WITHDRAWN
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Methylphenidate Hydrochloride (HCl) Extended Release Chewable Tablet (ERCT)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-intensity Laser Therapy Improves Pain, Health Status and Quality of Life in Women With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DEVICE: traditional exercise therapy only|DEVICE: HILT alongside traditional exercise therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Psyllium vs. Wheat Dextrin on Glycemic Control and Inflammatory Markets in Diabetes Mellitus 2
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Psyllium|DIETARY_SUPPLEMENT: Wheat Dextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Group- Versus Individual-Mindfulness-Based Cognitive Therapy: a Randomized Trial
Status: COMPLETED
Conditions: Depressive Symptoms
Interventions: BEHAVIORAL: Group-Mindfulness-Based Cognitive Therapy|BEHAVIORAL: Individual-Mindfulness-Based Cognitive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Patent Foramen Ovale Closure Improve Exercise Capacity & Prevent Blood Flow Through Intrapulmonary Shunt
Status: ENROLLING_BY_INVITATION
Conditions: Patent Foramen Ovale
Interventions: OTHER: PFO Closure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mithramycin for Lung, Esophagus, and Other Chest Cancers
Status: TERMINATED
Conditions: Lung Cancer|Esophageal Cancer|Mesothelioma|Gastrointestinal Neoplasms|Breast Cancer
Interventions: DRUG: Mithramycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Danish Non-vitamin K Antagonist Oral Anticoagulation Study in Patients With Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DRUG: Dabigatran Etexilate Oral Capsule|DRUG: Rivaroxaban Oral Tablet|DRUG: Edoxaban Oral Tablet|DRUG: Apixaban Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Norethisterone Enanthate on Recurrent Bacterial Vaginosis
Status: COMPLETED
Conditions: Bacterial Vaginosis|HIV
Interventions: DRUG: Norethisterone enantate|DEVICE: Condoms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Multiple Electrolytes Injection Ⅱ and Saline on Hyperchloremia in Patients With Aneurysmal Subarachnoid Hemorrhage:a Pilot Study
Status: COMPLETED
Conditions: Aneurysmal Subarachnoid Hemorrhage|Hyperchloremia
Interventions: DRUG: maintenance fluid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PAZOFOS: Phase Ib and Phase II Trial of Pazopanib +/- Fosbretabulin in Advanced Recurrent Ovarian Cancer
Status: TERMINATED
Conditions: Ovarian Neoplasms|Neoplasms, Ovarian|Ovarian Cancer
Interventions: DRUG: Pazopanib|DRUG: Fosbretabulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of In-line Microfilters on Systemic Inflammation in Adult Critically Ill Patients
Status: COMPLETED
Conditions: Systemic Inflammation
Interventions: DEVICE: In-line microfilter (Supor IV Filter; Pall Corporation, Port Washington, New York)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study To Investigate GW274150 Or Prednisolone In Rheumatoid Arthritis Taken Repeatedly For 28 Days.
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: GW274150|DRUG: Prednisolone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CTS-1027 in Interferon-Naive Hepatitis C Patients
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: ribavirin|DRUG: CTS-1027|DRUG: Placebo for ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opsens Optowire for Fractional Flow Reserve - The O2 Pilot Study
Status: COMPLETED
Conditions: Stable Angina|Unstable Angina Pectoris|Chest Pain|Ischemia
Interventions: DEVICE: Fractional flow reserve measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ultrasound and Pelvic Floor Muscle Training
Status: UNKNOWN
Conditions: Urinary Incontinence,Stress|Ultrasound|Elastography|Contraction; Pelvic|Urethral Hypermobility
Interventions: DIAGNOSTIC_TEST: perineal ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: T2DM (Type 2 Diabetes Mellitus)
Interventions: DRUG: HTD1801|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Allogenic Bone-Marrow Mesenchymal Stromal Cell Product StromaForte in Aging Frailty Patients
Status: RECRUITING
Conditions: Aging Frailty
Interventions: BIOLOGICAL: StromaForte
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Using a Video vs. a Text to Improve Secure Communication During a Crisis in Anesthesia
Status: NOT_YET_RECRUITING
Conditions: Simulation|Education|Communication
Interventions: OTHER: Video group|OTHER: Text group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Use of MMC During PRK and Its Effect on Postoperative Topical Steroid Requirements
Status: UNKNOWN
Conditions: Corneal Opacity
Interventions: DRUG: Mitomycin-C|DRUG: Fluorometholone 1% topical ocular steroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study for Fluticasone Propionate 250 mcg/Salmeterol Xinafoate 50 mcg Inhalation Powder in Healthy Volunteers
Status: ACTIVE_NOT_RECRUITING
Conditions: Bioequivalence
Interventions: DRUG: Fluticasone propionate 250 mcg and salmeterol xinafoate 50 mcg/Respirent Pharmaceuticals|DRUG: ADVAIR DISKUS® 250/50
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Surgical Septal Myectomy vs Percutaneous Transluminal Alcohol Septal Ablation in Patients With Hypertrophic Obstructive Cardiomyopathy
Status: RECRUITING
Conditions: Hypertrophic Cardiomyopathy
Interventions: PROCEDURE: Alcohol Septal Ablation|PROCEDURE: Surgical Septal Myectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Quizartinib in Japanese Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Quizartinib|DRUG: Cytarabine|DRUG: Idarubicin|DRUG: Daunorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FMT in Obesity: RYGB vs. LEAN vs. Autologous FMT
Status: RECRUITING
Conditions: Morbid Obesity|Metabolic Syndrome|Diabetes|PreDiabetes|Insulin Resistance
Interventions: PROCEDURE: Fecal microbiota transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Spinal Stimulation: Safety and Feasibility for Upper Limb Function in Children With Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Biostim-5 transcutaneous spinal stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Point of Care Ultrasound in Obstetric Triage
Status: RECRUITING
Conditions: Ultrasound|Fetal Monitoring
Interventions: OTHER: Continuous Fetal Monitoring|OTHER: Point of Care Handheld Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Safety and Efficacy Study Evaluating Dimebon (Latrepirdine) in Patients With Moderate to Severe Alzheimer's Disease
Status: TERMINATED
Conditions: Moderate to Severe Alzheimer
Interventions: DRUG: Dimebon (latrepirdine)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Venous Catheter Insertion Depth in Neonates
Status: COMPLETED
Conditions: Central Venous Catheterization
Interventions: DEVICE: UVC|DEVICE: UVC|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Optimal Technique for Determination of Renal Function of Critically Ill Patients
Status: COMPLETED
Conditions: Renal Function|Critical Illness
Interventions: PROCEDURE: Measurement of inulin clearance
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating the Safety of Long Term Dosing of Romiplostim (Formerly AMG 531) in Thrombocytopenic Subjects With Myelodysplastic Syndromes (MDS)
Status: COMPLETED
Conditions: Hematology|MDS|Myelodysplastic Syndromes|Thrombocytopenia
Interventions: DRUG: Romiplostim (formerly AMG 531)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This Study in Healthy Men Tests How Different Doses of BI 1323495 Are Taken up in the Body and How Well They Are Tolerated.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1323495|DRUG: BI 1323495|DRUG: BI 1323495|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Breast Cancer Study of Stereotactic Body Radiation Therapy (SBRT) Combined Neoadjuvant Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: SHR-1316 at a dose 20mg/kg q3w|DRUG: SHR6390 at a dose of 150mg orally, daily|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Augmentation of Meniscal Repair With Marrow Stimulation Techniques (Microfractures)
Status: COMPLETED
Conditions: Meniscus Lesion
Interventions: PROCEDURE: with microfractures|PROCEDURE: without microfractures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Screening for Atrial Fibrillation With Prolonged Continuous Single-lead ECG Devices in High-risk Patients
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DIAGNOSTIC_TEST: Prolonged continuous single-lead ECG monitor|DIAGNOSTIC_TEST: Intermittent ECG monitor|DIAGNOSTIC_TEST: Routine practice
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Purpose of This Research Study is to See if Combining Gemcitabine, Cisplatin and Durvalumab Chemotherapy Treatments With a Direct Tumor Therapy Yittrium-90 (Y-90) Will Work Better Together to Shrink Tumors and Control Cancer
Status: RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Induction Chemotherapy Triplet Therapy|RADIATION: Concurrent Y-90 treatment|DRUG: Consolidation Doublet Therapy:
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron and the Breast-Fed Infant: Iron Status and Two Regimens of Iron Supplementation
Status: COMPLETED
Conditions: Iron Deficiency
Interventions: DIETARY_SUPPLEMENT: Fer-In-Sol (ferrous sulfate)|DIETARY_SUPPLEMENT: Iron fortified cereal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Long-term Stability and Survival Rates of a Novel Oticon Medical Bone Conduction Device Implant
Status: COMPLETED
Conditions: Deafness|Hearing Loss|Hearing Loss, Conductive|Hearing Disorders|Ear Diseases|Otorhinolaryngologic Diseases
Interventions: DEVICE: Bone anchored hearing implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of LipoprotEin(a) in CardiovascuLar Diseases and Premature Acute Coronary Syndromes - (RELACS) Study
Status: RECRUITING
Conditions: Acute Coronary Syndrome|Lipoprotein Disorder|Acute Myocardial Infarction|Cardiovascular Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Does Oral Sildenafil (Viagra) Decrease Mean Pulmonary Artery Pressure After Cardiac Surgery?
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: Sildenafil|DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Constitutive IL7R (C7R) Modified Banked Allogeneic CD30.CAR EBVSTS for CD30-Positive Lymphomas
Status: NOT_YET_RECRUITING
Conditions: CD30-Positive Diffuse Large B-Cell Lymphoma|Anaplastic Large Cell Lymphoma, T Cell and Null Cell Type|Anaplastic Large Cell Lymphoma, ALK-Positive|Peripheral T-cell Lymphoma|Anaplastic Large Cell Lymphoma, ALK-negative|Non-Hodgkin Lymphoma|Hodgkin Lymphoma
Interventions: BIOLOGICAL: C7R.CD30.CAR-EBVST cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT