pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Acupressure on Postoperative Ileus in Patients With Colorectal Cancer Surgery
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: OTHER: Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Biodentine and Mineral Trioxide Aggregate in Revascularization of Non Vital Immature Anterior Teeth
Status: COMPLETED
Conditions: Pulp Necrosis
Interventions: DRUG: Biodentine|DRUG: Mineral Trioxide Aggregate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dasatinib Plus Quercetin for Accelerated Aging in Mental Disorders
Status: RECRUITING
Conditions: Schizophrenia|Treatment Resistant Depression|Aging, Premature
Interventions: DRUG: Dasatinib + quercetin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Response to and Safety of an 8-Day Course of Phenoptin™ Treatment in Subjects With Phenylketonuria
Status: COMPLETED
Conditions: Phenylketonurias
Interventions: DRUG: sapropterin dihydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adipose Derived SVF for Aero-digestive & Enterocutaneous Fistulae
Status: WITHDRAWN
Conditions: Tracheoesopharyngeal Fistula|Bronchoesophageal Fistula|Tracheoesophageal Fistula
Interventions: DRUG: SVF (Stromal Vascular Fraction)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigate the Effect of Tart Montmorency Cherry Juice (Prunus Cerasus) on Cerebral Blood Flow and Cognitive Function
Status: COMPLETED
Conditions: Cognitive Decline
Interventions: OTHER: Placebo|DIETARY_SUPPLEMENT: 60mL tart Montmorency cherry juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Study of Oral Vinorelbine in Subjects With Non-Hematologic Malignancies
Status: UNKNOWN
Conditions: Nonhematologic Malignancies
Interventions: DRUG: vinorelbine tartrate|DRUG: vinorelbine tartrate|DRUG: vinorelbine tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scapular Blackburn Stabilization Versus PNF in Impingement Syndrome
Status: NOT_YET_RECRUITING
Conditions: Impingement Syndrome
Interventions: OTHER: scapular Blackburn stabilization plus exercise|OTHER: PNF plus Exercise|OTHER: exercise only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of NIO752 in Early Alzheimer's Disease Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease|Mild Cognitive Impairment
Interventions: DRUG: NIO752|DRUG: NIO752|DRUG: Matching placebo|DRUG: NIO752
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sublobar Resection Versus Lobectomy for cT1N0M0 Non-small-cell Lung Cancer
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: PROCEDURE: sublobar resection|PROCEDURE: lobectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Bilateral Plane Block in Total Laparoscopic Hysterectomy : A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Block
Interventions: DRUG: Bupivacaina 0.5%|DRUG: placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect Site Controlled, Reaction Time Safeguarded, Patient Maintained Sedation With Propofol in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Propofol|DEVICE: Patient maintained sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of OT-551 Eye Drops to Prevent or Delay Progression of Nuclear Cataracts Following Vitreous Removal
Status: TERMINATED
Conditions: Epiretinal Membrane|Macular Hole
Interventions: DRUG: OT-551 ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Parallel Study Between BMP-2 and Autologous Bone Graft After Ilizarow Treatment
Status: COMPLETED
Conditions: Bone Degenerative Changes|Osteoarthritis|Degenerative Disorder of Bone
Interventions: DRUG: Bone Morphogenetic Protein 2|PROCEDURE: Autologous bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Structural and Functional Networks in ALS: An Insight Into Pseudobulbar Affect
Status: NOT_YET_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis|Pseudobulbar Affect
Interventions: OTHER: Diffusion Kurtosis Imaging (DKI)|OTHER: Resting State Magnetoencephalography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Umbilical Cord Mesenchymal Stem Cells in the Treatment of Moderate/Severe Chronic Graft-versus-host Disease
Status: UNKNOWN
Conditions: Graft Vs Host Disease
Interventions: BIOLOGICAL: Umbilical Cord Mesenchymal Stem Cell Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: European Multicenter Study on Surgical Management of Advanced Thyroid Cancer
Status: RECRUITING
Conditions: Thyroid Carcinoma|Thyroid Cancer|Thyroid Neoplasms|Thyroid Cancer, Papillary|Thyroid Cancer, Follicular|Thyroid Medullary Carcinoma|Anaplastic Thyroid Cancer
Interventions: PROCEDURE: Thyroidectomy with or without lymphadenectomy or multivisceral resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Refitting Multifocal Contact Lens Wearers With a Different Multifocal Contact Lens
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: Lens 1|DEVICE: Lens 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TTField in Combination With Temozolomide and Tislelizumab in The Treatment of Newly Diagnosed Glioblastoma.
Status: RECRUITING
Conditions: Glioblastoma Multiforme
Interventions: DEVICE: Tumor Treating Fields|DRUG: Tislelizumab|DRUG: Temozolomide (TMZ)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety of ViaDerm-hPTH(1-34) Compared to Forteo SC in Postmenopausal Women With Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Teriparatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Value of Liquid Potassium Magnesium Citrate in Controlling Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Potassium chloride powder|DRUG: Potassium magnesium Citrate (KMgCit)|DRUG: Potassium citrate powder|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Dosing Regimens of Temozolomide in Patients With Progressive or Recurrent Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: Temozolomide in both arms|DRUG: Temozolomide in both arms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RPL554 Drug Administered by Metered Dose Inhaler to Treat Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Part A: RPL554|DRUG: Placebos|DRUG: Part B: RPL554
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection
Status: TERMINATED
Conditions: HSIL, High-Grade Squamous Intraepithelial Lesions|Human Papilloma Virus Infection|HIV Infection|Anal Cancer|Anus Neoplasm
Interventions: DRUG: Topical ABI-1968 cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LinkPositively+ A Mobile Health App Delivered Intervention to Improve HIV Care Outcomes Among Black Women Affected by Mental Health and Violence
Status: RECRUITING
Conditions: HIV/AIDS|Mental Health Issue
Interventions: BEHAVIORAL: LPP+: Mindfulness Meditation Delivered|BEHAVIORAL: LP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Determine the Role of Prokinetics in Feed Intolerance in Critically Ill Cirrhosis
Status: COMPLETED
Conditions: Cirrhosis
Interventions: DRUG: Metaclopramide|DRUG: Erythromycin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mifepristone and Misoprostol Versus Misoprostol Alone in the Medical Management of Missed Miscarriage
Status: COMPLETED
Conditions: Missed Miscarriage
Interventions: DRUG: Mifepristone, Oral, 200 Mg|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of LUM001 in the Treatment of Cholestatic Liver Disease in Patients With Alagille Syndrome
Status: COMPLETED
Conditions: Alagille Syndrome
Interventions: DRUG: LUM001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: In Vitro Activation of Dormant Follicles for Patients With Primary Ovarian Insufficiency
Status: UNKNOWN
Conditions: in Vitro Activation|Dormant Follicle|Primary Ovarian Insufficiency|Ovarian Resistance Syndrome
Interventions: PROCEDURE: Ovariotomy|PROCEDURE: Activate dormant follicles|PROCEDURE: Ovary tissue transplantation|PROCEDURE: Ovarian superficial cut
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of a Single Dose of ALXN1210 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ALXN1210|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase I Study to Evaluate BFPET as a Potential Myocardial Perfusion Imaging(MPI) Agent for PET
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: BFPET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bariatric Surgery and Consequences for Mother and Baby in Pregnancy
Status: COMPLETED
Conditions: Hypoglycemia Non-Diabetic|Gastric Bypass Status Complicating Pregnancy, Birth, or Puerperium
Interventions: DIAGNOSTIC_TEST: Mixed meal test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neoadjuvant Chemotherapy for Resectable Cancer of the Pancreatic Head
Status: COMPLETED
Conditions: Cancer of the Pancreatic Head
Interventions: DRUG: Gemcitabine / Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Manual Therapy and Scapular Exercise for the Pectoralis Minor in Individuals With Shoulder Pain
Status: COMPLETED
Conditions: Shoulder Pain|Shoulder Impingement|Scapular Dyskinesis
Interventions: PROCEDURE: pectoralis minor intervention group|PROCEDURE: shoulder strengthening group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Concurrent Hookah and Alcohol Consumption on Smoking Topography and Toxicant Exposure
Status: COMPLETED
Conditions: Alcohol Use, Unspecified|Hookah Smoking
Interventions: OTHER: Active alcohol consumption|OTHER: Placebo consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multiomics After Headache Provocation of People Who Are Unable to Have Headache
Status: COMPLETED
Conditions: Headache|Healthy
Interventions: DRUG: Isosorbide Mononitrate 60 MG Extended Release Oral Tablet [Imdur]|OTHER: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ascending Dose Study of Genome Editing by Zinc Finger Nuclease Therapeutic SB-FIX in Subjects With Severe Hemophilia B
Status: TERMINATED
Conditions: Hemophilia B
Interventions: BIOLOGICAL: SB-FIX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Probiotic Lactobacillus Reuteri Prodentis Consumption on Gingival Crevicular Fluid Inflammatory Response and Metagenomic Profiles of Oral Microbiome in Orthodontic Patients.
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Subjects With Fixed Orthodontics
Interventions: DIETARY_SUPPLEMENT: BioGaia Probiotic Lozenges
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Safety and Tolerability of Valproic Acid in Healthy Volunteers (Part 1)
Status: COMPLETED
Conditions: Shock,Hemorrhagic
Interventions: DRUG: Valproic Acid|DRUG: Isotonic saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Basal Bolus vs. Sliding Scale for Treatment of Diabetic Patients in Medical Wards
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Insulin, regular - act rapid|DRUG: Insulin glulisine, Insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anatomical and Physiological Characterisation of the Gut Endocrine Cells in Healthy and in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: PROCEDURE: Double-balloon enteroscopy (DBE) with biopsy retrieval
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of LEE011, BYL719 and Letrozole in Advanced ER+ Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: LEE011|DRUG: Letrozole|DRUG: BYL719
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Evaluation of Topical AL-60371 Otic Suspension, 0.3% in the Treatment of Acute Otitis Externa
Status: COMPLETED
Conditions: Acute Otitis Externa
Interventions: DRUG: AL-60371, 0.3% otic suspension|DRUG: AL-60371 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Modulating Brain Activity to Improve Goal-directed Physical Activity in Older Adults
Status: COMPLETED
Conditions: Aging
Interventions: DEVICE: Transcranial direct current stimulation (tDCS)|DEVICE: Sham stimulation|BEHAVIORAL: Behavioral intervention to increase physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ramucirumab in Participants With Gastric, Esophageal, and Gastroesophageal Cancer
Status: COMPLETED
Conditions: Stomach Cancer|Esophageal Cancer
Interventions: BIOLOGICAL: Ramucirumab|DRUG: Placebo|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adopting the MRD Strategy to Optimize Post-operation Adjuvant Therapies for Early Stage Breast Cancer
Status: RECRUITING
Conditions: Early-stage Breast Cancer
Interventions: OTHER: The MRD strategy for high risk or MRD+ TNBC patients|OTHER: The MRD strategy for high risk or MRD+ HER2+ patients|OTHER: The MRD strategy for high risk or MRD+ ER+ patients|OTHER: The MRD strategy for low risk and MRD- TNBC patients|OTHER: The MRD strategy for low risk and MRD- HER2+ patients|OTHER: The MRD strategy for low risk and MRD- ER+ patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulation of SERCA2a of Intra-Myocytic Calcium Trafficking in Cardiomyopathy Secondary to Duchenne Muscular Dystrophy
Status: NOT_YET_RECRUITING
Conditions: DMD-Associated Dilated Cardiomyopathy
Interventions: GENETIC: SRD-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blackcurrants Modify Gut Microbiota and Reduce Osteoporosis and CVD Risk
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis|Gut Microbiota|Cardiovascular Diseases
Interventions: DRUG: blackcurrant (BC) extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of a Mixed Chinese Herbal Formula on Atopic Dermatitis
Status: NOT_YET_RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: Chinese herbal formula (CHF)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Assess Safety and Efficacy of Lenvatinib (18 mg vs. 14 mg) in Combination With Everolimus in Participants With Renal Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: DRUG: lenvatinib|DRUG: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Insertion of Sheath Before Angiography or Angioplasty
Status: TERMINATED
Conditions: Radial|Angioplasty|Angiography|Ultrasound|Randomized
Interventions: DIAGNOSTIC_TEST: Ultrasound guided sheath insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Abbott Vascular Medical Device Registry
Status: RECRUITING
Conditions: Acute Myocardial Infarction|Restenoses, Coronary|Coronary Artery Lesions|Venous Embolism|Arterial Embolism
Interventions: DEVICE: Coronary and peripheral stents|DEVICE: Pacing catheters|DEVICE: Vascular plugs|DEVICE: Measurement and imaging (FFR and OCT)|DEVICE: Peripheral dilatation catheters|DEVICE: Coronary dilatation catheters|DEVICE: Coronary and peripheral guidewires|DEVICE: Vessel closure/compression devices|DEVICE: Vascular access introducers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Project to Improve the Diagnosis and Prognosis of Myocardial Injury Associated to Non Cardiac Surgery
Status: COMPLETED
Conditions: Myocardium; Injury
Interventions: DIAGNOSTIC_TEST: Troponin|DRUG: Acetylsalicylic acid|DRUG: Statin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: UB-621, a New Type of Anti-herpes Simplex Virus (HSV) Monoclonal Antibody for the Use in the Treatment of Adult Recurrent HSV-2 Infections of the Genitals
Status: NOT_YET_RECRUITING
Conditions: Recurrent Genital Herpes
Interventions: BIOLOGICAL: UB-621
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Folfirinox for Resectable Pancreatic Adenocarcinoma - A Phase II Study
Status: TERMINATED
Conditions: Pancreatic Adenocarcinoma|Poorly Differentiated Malignant Neoplasm|Resectable Pancreatic Cancer|Stage IA Pancreatic Cancer|Stage IB Pancreatic Cancer|Stage IIA Pancreatic Cancer|Stage IIB Pancreatic Cancer|Stage III Pancreatic Cancer|Undifferentiated Pancreatic Carcinoma
Interventions: DRUG: Irinotecan Hydrochloride|DRUG: Oxaliplatin|DRUG: Leucovorin Calcium|DRUG: Fluorouracil|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protocol GELLC-7: Ibrutinib Followed by Ibrutinib Consolidation in Combination With Ofatumumab
Status: UNKNOWN
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Ibrutinib 140 MG Oral Capsule [Imbruvica]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Interventions to Teach Melanoma Patients Skin Self-examination
Status: COMPLETED
Conditions: Melanoma
Interventions: BEHAVIORAL: In-person counseling|BEHAVIORAL: Workbook|BEHAVIORAL: Tablet Computer-Based Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Fibroids and Infertility - a Study of the Significance of Removal of Fibroids With Regard to Endometrial Receptivity
Status: RECRUITING
Conditions: Leiomyoma, Uterine
Interventions: PROCEDURE: Transcervical resection of fibroids|PROCEDURE: Myomectomy per laparoscopy or laparotomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radial Versus Femoral Access For Thrombectomy in Patients With Acute Basilar Artery Occlusion
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: PROCEDURE: endovascular recanalization via radial approach|PROCEDURE: endovascular recanalization via femoral approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dosing Strategies for Automated Mandatory Intermittent Boluses Technique for Epidural Labour Analgesia
Status: WITHDRAWN
Conditions: Primigravida in Labour Pains
Interventions: DRUG: Bupivacaine-Fentanyl Mixture|DRUG: Bupivacaine-Fentanyl Mixture|DRUG: Bupivacaine-Fentanyl Mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Psychomotor Vigilance Testing in the Assessment of Pediatric Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Pediatric Obstructive Sleep Apnea
Interventions: DEVICE: Psychomotor Vigilance Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Post-operative Ovarian Adhesion Study in Women With Endometriosis
Status: UNKNOWN
Conditions: Endometriosis
Interventions: DEVICE: Anti-adhesive gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of SenL-T7 CAR T Cells in the Treatment of Relapsed and Refractory CD7+ T-cell Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: SenL-T7 CAR T Cells for CD7+ T-cell Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma
Interventions: BIOLOGICAL: Senl-T7
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Image Guided Hypofractionated Radiation Therapy, Nelfinavir Mesylate, Pembrolizumab, Nivolumab and Atezolizumab in Treating Patients With Advanced Melanoma, Lung, or Kidney Cancer
Status: TERMINATED
Conditions: Metastatic Kidney Carcinoma|Recurrent Lung Non-Small Cell Carcinoma|Stage IV Cutaneous Melanoma AJCC v6 and v7|Stage IV Renal Cell Cancer AJCC v7|Stage IV Lung Non-Small Cell Cancer AJCC v7
Interventions: DRUG: Atezolizumab|RADIATION: Hypofractionated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|DRUG: Nelfinavir Mesylate|BIOLOGICAL: Nivolumab|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regorafenib and PD-1 Antibody in Combination With Radiotherapy for pMMR/MSS Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer Metastatic|MSS
Interventions: DRUG: Regorafenib and PD-1 antibody in Combination with Radiotherapy|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of AI R&D Tool in Adult Glioma and Other Primary Brain Tumours (PEAR-GLIO)
Status: RECRUITING
Conditions: Brain Tumor|Glioma, Malignant|Ependymoma|Oligodendroglioma|Glioblastoma
Interventions: PROCEDURE: Resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ISCHEMIA-Chronic Kidney Disease Trial
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Artery Disease|Heart Diseases|Myocardial Ischemia|Kidney Disease|End Stage Renal Failure on Dialysis
Interventions: PROCEDURE: Cardiac Catheterization|PROCEDURE: Coronary Artery Bypass Graft Surgery|PROCEDURE: Percutaneous Coronary Intervention|BEHAVIORAL: Lifestyle|DRUG: Medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MFR Versus PFS Techniques on Pain,Range of Motion And Disability in Chronic Non Specific Low Back Pain.
Status: COMPLETED
Conditions: Chronic Non Specific Low Back Pain
Interventions: OTHER: Myofascial Release technique|OTHER: Post facilitation stretch .
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selective Internal Radiation Therapy (SIRT) Versus Transarterial Chemoembolisation (TACE) for the Treatment of Hepatocellular Carcinoma (HCC).
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: DEB TACE|PROCEDURE: SIRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CMV Glycoprotein B Vaccine in Allograft Recipients
Status: UNKNOWN
Conditions: Cytomegalovirus Infections
Interventions: BIOLOGICAL: CMV gB vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: IMAGE-HF Project I-A: Cardiac Imaging in Ischemic Heart Failure (AIMI-HF)
Status: COMPLETED
Conditions: Heart Failure|Coronary Artery Disease|Ischemic Cardiomyopathy
Interventions: OTHER: Advanced cardiac imaging|OTHER: Standard Cardiac Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Metabolic Effects of Melatonin in Patients Treated With Second Generation Antipsychotics
Status: COMPLETED
Conditions: Second Generation Antipsychotic Induced Metabolic Adverse Effects
Interventions: DRUG: Melatonin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Avelumab in Combination With Axitinib In Non-Small Cell Lung Cancer (NSCLC) or Urothelial Cancer (Javelin Medley VEGF)
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer|Urothelial Cancer
Interventions: DRUG: Avelumab (MSB0010718C)|DRUG: Axitinib (AG-013736)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lithium Therapeutic Drug Monitoring; Once Daily Vs Twice Daily Dosing and the Impact of Kidney Function
Status: UNKNOWN
Conditions: Bipolar Disorder|Major Depressive Disorder
Interventions: DIAGNOSTIC_TEST: Lithium level|DIAGNOSTIC_TEST: Serum Creatinine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Receptor Radionuclide Therapy With 177Lu-DOTATOC
Status: RECRUITING
Conditions: Neuroendocrine Tumors|Paraganglioma|Pheochromocytoma
Interventions: DRUG: 177Lu-DOTATOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of MK0991 (Caspofungin) in Japanese Patients With Deep-seated Candida or Aspergillus Infections (0991-062)(COMPLETED)
Status: COMPLETED
Conditions: Fungal Infection
Interventions: DRUG: caspofungin acetate|DRUG: Comparator: Micafungin sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early EMDR Following Covid-19 Critical Illness: A Feasibility Trial
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder|Intensive Care Psychiatric Disorder|Anxiety Disorders|Depression|Critical Care|COVID
Interventions: OTHER: Eye Movement Desensitisation and Reprocessing Recent traumatic Event Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study Using Eye Lipid Mobilizer (ELM) With Heat and Vibration To Treat Evaporative Dry Eye Disease
Status: COMPLETED
Conditions: Evaporative Dry Eye Disease|Meibomian Gland Dysfunction
Interventions: DEVICE: ELM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
Status: RECRUITING
Conditions: Solid Tumors
Interventions: DRUG: INCB161734|DRUG: Cetuximab|DRUG: Retifanlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Efficacy in Adult Subjects With ITP
Status: COMPLETED
Conditions: Immune Thrombocytopenic Purpura
Interventions: DRUG: BMS-986004 75 mg IV|DRUG: BMS-986004 225 mg IV|DRUG: BMS-986004 675 mg IV|DRUG: BMS-986004 1500 mg IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quercetin Phytosome® Chronic Fatigue Symptoms
Status: COMPLETED
Conditions: Chronic Fatigue Symptoms|Sleep|Physical Performance|Body Composition
Interventions: DIETARY_SUPPLEMENT: Quercetin group|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intraluminal Endosonography for Examination of the Structural Changes of the Stomach in Gastroparetic Patients
Status: COMPLETED
Conditions: Idiopathic Gastroparesis|Diabetic Gastroparesis
Interventions: PROCEDURE: Endoscopic Ultrasound Fine Needle Aspiration (EUS-FNA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate Efficacy and Safety of LIB003 in Patients on Lipid-Lowering Therapy Needing Additional LDL-C Reduction
Status: COMPLETED
Conditions: LDL Cholesterol
Interventions: BIOLOGICAL: LIB003
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acyclovir for Herpes Infections Involving the Central Nervous System in Neonates
Status: COMPLETED
Conditions: Herpes Simplex
Interventions: DRUG: Acyclovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcranial Direct Current Stimulation (tDCS) on Motor Function in Schizophrenia Patients and Individuals at Risk for Psychotic Onset
Status: RECRUITING
Conditions: Schizophrenia|Psychosis|Parkinsonism|Dyskinesias
Interventions: DEVICE: Transcranial direct current stimulation device (Soterix Medical, New York, NY)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Local Anaesthesia Versus Local Anaesthesia and Conscious Sedation for Hernioplasty
Status: UNKNOWN
Conditions: Inguinal Hernia|Anesthesia, Local|Conscious Sedation
Interventions: DRUG: Midazolam|DRUG: Intravenous Normal Saline|DRUG: Bupivocaine|DRUG: Lignocaine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Four-week Clinical Trial Investigating Efficacy and Safety of Cannabidiol as a Treatment for Acutely Ill Schizophrenic Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: Cannabidiol|DRUG: Olanzapine|DRUG: Placebo Cannabidiol|DRUG: Placebo Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Acupressure at Sanyinjiao Point on Primary Dysmenorrhea Among University Students.
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Dysmenorrhea|Acupuncture
Interventions: OTHER: acupressure at Sanyinjiao point
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Accuracy and Reliability of Measurements Made on CBCT and IOS Images With Their made-on Plaster Models.
Status: COMPLETED
Conditions: Malocclusion
Interventions: DIAGNOSTIC_TEST: Plaster models|DIAGNOSTIC_TEST: CBCT images|DIAGNOSTIC_TEST: IOS images
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dual Modulation of Sigma-1 and NMDA Receptors in the Treatment of Schizophrenia
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: S1RA plus NMDAE|DRUG: S1RA plus Placebo Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of AZD2171 co-Administered With Fixed Multiple Oral Doses of ZD1839 in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Advanced Tumor
Interventions: DRUG: AZD2171|DRUG: ZD1839
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioavailability of Diclofenac Sodium 50 mg Enteric-Coated Tablets Under Non-Fasting Conditions
Status: COMPLETED
Conditions: Inflammation
Interventions: DRUG: Diclofenac Sodium 50 mg Tablets Under Fasting Conditions (Geneva Pharmaceuticals, Inc)|DRUG: Diclofenac Sodium 50 mg Tablets Under Fed Conditions (Geneva Pharmaceuticals, Inc)|DRUG: Voltaren 50 mg Tablets Under Fed Conditions (Geigy Pharmaceuticals)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Audio-vestibular Evaluation of Children and Young Adults With Osteogenesis Imperfecta
Status: RECRUITING
Conditions: Osteogenesis Imperfecta
Interventions: DIAGNOSTIC_TEST: Vestibular Assessment|DIAGNOSTIC_TEST: Petrous bone Computed Tomography (CT)|DIAGNOSTIC_TEST: Magnetic Resonance Imaging (MRI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tumor-specific T Cells in Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: PROCEDURE: Bone marrow aspiration from the iliac crest|DEVICE: Illinois bone marrow aspiration neddle
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination With Sintilimab and XELOX+Bevacizumab as 1st Line Therapy in RAS-mutant Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer Stage IV
Interventions: DRUG: Sintilimab Injection|DRUG: Control Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protective Effects of Oral L-Arginine CI-AKI
Status: UNKNOWN
Conditions: Contrast Induced AKI
Interventions: DIETARY_SUPPLEMENT: L-arginine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Testing Implementation Strategies to Improve Delivery of PrEP for Pregnant and Postpartum Women in Kenya
Status: COMPLETED
Conditions: Pre-Exposure Prophylaxis|HIV Infections|Pregnancy Related
Interventions: OTHER: PrEP Optimization Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Moxibustion for Knee Osteoarthritis
Status: COMPLETED
Conditions: Idiopathic Osteoarthritis
Interventions: OTHER: Moxibustion treatment plus usual care|OTHER: Usual care alone group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19
Status: COMPLETED
Conditions: COVID|Covid-19|Coronavirus|Coronavirus Infection|Severe Acute Respiratory Syndrome|Severe Acute Respiratory Syndrome Coronavirus 2|Sars-CoV2|Ards|Acute Respiratory Distress Syndrome
Interventions: DRUG: APL-9|OTHER: Vehicle Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Menstrual Blood Proteomic Profile in Women With Endometriosis (PROTEO-ENDO) Study
Status: RECRUITING
Conditions: Endometriosis|Endometriosis Ovary|Endometriosis-related Pain
Interventions: DIAGNOSTIC_TEST: Peripheral blood sample|DIAGNOSTIC_TEST: Menstrual Blood sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Bioequivalence Study Between the Proposed and Current Talazoparib Capsule Formulation and Food Effect Study for the Proposed Talazoparib Capsule Formulation in Participants With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors|Solid Tumors|Ovarian Cancer|Breast Cancer|Prostate Cancer|NSCLC|Pancreatic Cancer|Colorectal Cancer
Interventions: DRUG: TALZENNA capsule|DRUG: Talazoparib soft gel capsule|DRUG: Talazoparib soft gel capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Prevention and Treatment of Postoperative Metastasis of Lung Cancer by Fuzheng Quxie Recipe
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Fuzheng Quxie Recipe|DRUG: Fuzhengquye Fang Recipe simulant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase IV, Two-part, Open-label Study Assessing the Pharmacokinetics, Safety and Pharmacodynamics of Spironolactone Oral Suspension in Pediatric Patients
Status: NOT_YET_RECRUITING
Conditions: Edema Due to Heart Failure or Cirrhosis
Interventions: DRUG: Spironolactone Oral Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Priming Before Induction Termination of Pregnancy
Status: COMPLETED
Conditions: Abortion, Induced|Abortion, Second Trimester
Interventions: DRUG: Addition of misoprostol 25 mcg 12 hours before induction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of ALIC/NAcc-DBS for Treatment-refractory OCD
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: deep brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Safety and Efficacy of Therapeutic HSV-2 Vaccine
Status: COMPLETED
Conditions: Genital Herpes Simplex Type 2
Interventions: BIOLOGICAL: GEN-003 Vaccine (30μg of each antigen)|BIOLOGICAL: GEN-003 Vaccine (60μg of each antigen)|BIOLOGICAL: Matrix-M2 Adjuvant (25μg)|BIOLOGICAL: Matrix-M2 Adjuvant (50μg)|BIOLOGICAL: Matrix-M2 Adjuvant (75μg)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label, Randomized Study in a Pediatric Population in a JEV (Japanese Encephalitis Virus)-Endemic Country
Status: COMPLETED
Conditions: Japanese Encephalitis
Interventions: BIOLOGICAL: IXIARO|BIOLOGICAL: IXIARO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of SHP655 (rADAMTS13) in Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: TAK-755|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Reflexology and Knee Massage With Black Cumin Oil on Pain and Fatigue
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: COMBINATION_PRODUCT: Knee Massage With Black Cumin Oil Group:|COMBINATION_PRODUCT: Foot Reflexology Group With Black Cumin Oil|COMBINATION_PRODUCT: placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vivo Prediabetes Study: Online, Live, and Interactive Strength Training for Older Adults With Prediabetes
Status: COMPLETED
Conditions: PreDiabetes|Older Adults|Muscle Loss|Muscle Weakness
Interventions: BEHAVIORAL: Vivo workout
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pregabalin as an add-on Therapy to Carbamazepine in Trigeminal Neuralgia Patients
Status: RECRUITING
Conditions: Trigeminal Neuralgia
Interventions: DRUG: Pregabalin and Carbamazepine|DRUG: Carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Enzalutamide in Indian Patients With Progressive Metastatic Castration-Resistant Prostate Cancer (mCRPC) Previously Treated With Docetaxel-Based Chemotherapy
Status: COMPLETED
Conditions: Metastatic Castration Resistant Prostate Cancer
Interventions: DRUG: Enzalutamide|DRUG: Androgen deprivation therapy (ADT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of AP707 in Patients With Chronic Back Pain
Status: RECRUITING
Conditions: Pain|Pain Syndrome|Pain, Chronic|Chronic Pain|Chronic Pain Syndrome|Back Pain|Lower Back Pain|Lower Back Pain Chronic
Interventions: DRUG: Adezunap (AP707)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Tailored Treatment in Elderly Patients With Newly Diagnosed Primary Lymphoma of Central Nervous System
Status: RECRUITING
Conditions: Primary Central Nervous System Lymphoma
Interventions: DRUG: Rituximab|DRUG: Methotrexate|DRUG: Procarbazine|DRUG: Lenalidomide|RADIATION: Radiotherapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aerobic Interval and Moderate Continuous Exercise Training on Ventricular Functions
Status: COMPLETED
Conditions: Healthy|High Intensity Interval Training|Exercise Training
Interventions: BEHAVIORAL: High intensity-interval training (HIIT)|BEHAVIORAL: Moderate intensity-continuous (MICT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The ROSE Scale-up Study: Informing a Decision About ROSE as Universal PPD Prevention
Status: RECRUITING
Conditions: Postpartum Depression
Interventions: BEHAVIORAL: ROSE (Reach Out, Stay Strong, Essentials for mothers of newborns)|BEHAVIORAL: Enhanced Care as Usual (CAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION