pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Mobile Behavioral Parent Training for Childhood ADHD: Pilot Trial
Status: NOT_YET_RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Mobile Behavioral Parent Training (mBPT)|BEHAVIORAL: Just-in-time intervention: Parenting Strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Variable Effects of Anti-diabetics on Stress Hyperglycemia Ratio
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Sitagliptin/metformin ( 50/500mg) Oral Tablet|DRUG: Empagliflozin/metformin(10/500mg) Oral Tablet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A New System for GERD Diagnosis and Treatment
Status: UNKNOWN
Conditions: GERD
Interventions: PROCEDURE: Stretta|PROCEDURE: Laparoscopic Nissen fundoplication|DRUG: Probiotic Agent|DRUG: PPI|DRUG: Prokinetic Motility Agents|DRUG: Neuromodulators
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of an Exercise Program and Education Through a Mobile Application for the Management of Patients With Hand Osteoarthritis and Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis - Hand Joint|Osteoarthritis Hand|Pain|Mobility Limitation|Stiffness of Hand, Not Elsewhere Classified
Interventions: OTHER: Smartphone Application|OTHER: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trail for Post Laparoscopic Pain
Status: UNKNOWN
Conditions: Shoulder Pain
Interventions: PROCEDURE: Combined maneuver|PROCEDURE: Intraperitoneal infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neurotronic Ablation of Arteries for the Treatment of Type 2 Diabetes Mellitus and Its Comorbidities
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus With Circulatory Complciation
Interventions: DEVICE: The Neurotronic arterial ablation catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influenza Virus Challenge Study to Test Monoclonal Antibody TCN-032 as a Treatment for Influenza
Status: UNKNOWN
Conditions: Influenza
Interventions: BIOLOGICAL: TCN-032|BIOLOGICAL: Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: tDCS in Post-stroke Neglect Rehabilitation
Status: RECRUITING
Conditions: Stroke|Neglect, Hemispatial
Interventions: DEVICE: Transcranial direct current stimulation|PROCEDURE: Neuropsychological rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Ruminococcus Torques Strain Bacterium in Healthy Adults.
Status: COMPLETED
Conditions: Overweight|Healthy
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: Ruminococcus torques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Improvement of the Selenium Supply in a Vegan Diet by Different Selenium Sources
Status: RECRUITING
Conditions: Diet, Vegan|Selenium
Interventions: DIETARY_SUPPLEMENT: selenium supplement|DIETARY_SUPPLEMENT: Brazil nut|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Analysis Using the Collagen Matrix and Autogenous Graft: Clinical Course, Aesthetic Results
Status: ACTIVE_NOT_RECRUITING
Conditions: Soft Tissue Atrophy
Interventions: PROCEDURE: Soft tissue augmentation with CTG|PROCEDURE: Soft tissue augmentation with CM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nateglinide: a Double Blind Add-on Study With Pioglitazone for Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Diabetes Mellitus, Type II
Interventions: DRUG: nateglinide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of Adaptive Radiotherapy Boost for HNSCC
Status: RECRUITING
Conditions: Squamous Cell Carcinoma|Head and Neck Cancer
Interventions: RADIATION: Intensity-modulated radiotherapy|OTHER: Magnetic Resonance Guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance Fedratinib to Prevent Post-Transplant Relapse in Myeloproliferative Neoplasms
Status: RECRUITING
Conditions: Myeloproliferative Neoplasm
Interventions: DRUG: Fedratinib Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole-Body Hyperthermia Plus Chemotherapy in Treating Patients With Advanced Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: carboplatin|DRUG: etoposide|DRUG: ifosfamide|PROCEDURE: hyperthermia treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Andecaliximab as Add-On Therapy to a Tumor Necrosis Factor Inhibitor and Methotrexate Regimen in Adults With Moderately to Severely Active Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Andecaliximab|DRUG: Placebo|DRUG: Methotrexate|DRUG: TNF Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pulsed Short Wave in Females With Knee Osteoarthritis
Status: COMPLETED
Conditions: Chronic Diseases|Knee Osteoarthritis
Interventions: DEVICE: Pulsed short wave
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application of Transcranial Direct Current Stimulation (tDCS) in Patients With Chronic Pain After Spinal Cord Injury
Status: TERMINATED
Conditions: Spinal Cord Injury
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-operative Pain Management in Children With Supracondylar Humerus Fractures
Status: ENROLLING_BY_INVITATION
Conditions: Supracondylar Humerus Fracture
Interventions: DRUG: Ibuprofen|DRUG: Hydrocodone/acetaminophen|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Speed of Robotic Leg Movements and Orthostatic Hypotension in Subacute SCI
Status: RECRUITING
Conditions: Spinal Cord Injuries|Orthostatic Hypotension
Interventions: DEVICE: ErigoPro
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Disease Management Training and Telephone Counseling Service for Elderly Patients With Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: BEHAVIORAL: Online education and Phone Counseling Service
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gemcitabine, Bevacizumab, and Abdominal Radiation Therapy in Treating Patients With Localized Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: gemcitabine|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double Blind, Parallel Group, Placebo Controlled, Multi-Center Study of the Efficacy and Safety of Cetirizine HCl Syrup vs. Loratadine Syrup vs. Placebo in Treatment of Children With Seasonal Allergic Rhinitis (SAR)
Status: COMPLETED
Conditions: Allergic Rhinitis|Hay Fever|SAR|Rhinitis, Allergic, Seasonal
Interventions: DRUG: Cetirizine|DRUG: Loratadine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quality-Assured Follow-up of Quiescent Neovascular Age -Related maculaR dEgeneration by Non-medical Practitioners
Status: UNKNOWN
Conditions: AMD
Interventions: DIAGNOSTIC_TEST: OCT|DIAGNOSTIC_TEST: Visual Acuity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pre-operative SABR With and Without Caloric Restriction for Early Stage Breast Cancer
Status: RECRUITING
Conditions: Anatomic Stage 0 Breast Cancer AJCC v8|Anatomic Stage 1 Breast Cancer AJCC v8|Anatomic Stage 2 Breast Cancer AJCC v8|Anatomic Stage 3 Breast Cancer AJCC v8|Breast Ductal Carcinoma in Situ|Invasive Breast Carcinoma|Triple Negative Breast Carcinoma
Interventions: OTHER: Best Practice|RADIATION: Stereotactic Body Radiation Therapy|PROCEDURE: Resection|PROCEDURE: Sentinel Lymph Node Biopsy|OTHER: Dietary Intervention|OTHER: Questionnaire Administration|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Pemetrexed and Gemcitabine for Patients With a New Diagnosis of Extensive-Stage Small Cell Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Small Cell
Interventions: DRUG: pemetrexed and gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Constitution of a Biological Cohort Following Bone Marrow Sampling From MDS or AML Patients and Age-matched Healthy Donors
Status: TERMINATED
Conditions: Myelodysplastic Syndromes|Acute Myeloid Leukemia|Cardio-vascular Surgery
Interventions: OTHER: Bone marrow analyses
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Body Surface Area-based vs Concentration-based Dosing of Cisplatin for Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Women With Advanced Ovarian Cancer
Status: RECRUITING
Conditions: FIGO Stage III Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Carcinoma
Interventions: DRUG: Cisplatin 100 mg/m2|DRUG: Cisplatin 40 mg/l
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Up-Down Determination of the ED90 of Metaraminol to Treat Hypotension During Cesarean Section
Status: COMPLETED
Conditions: Hypotension
Interventions: DRUG: Metaraminol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Neovascular AMD: Artificial Intelligence in Real-world Setting
Status: RECRUITING
Conditions: Exudative Macular Degeneration
Interventions: DRUG: anti-VEGF agent|DRUG: anti-VEGF agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Personality-targeted Interventions for Adolescent Alcohol Misuse
Status: COMPLETED
Conditions: Alcohol Abuse|Drug Abuse|Depression|Panic Disorder|Conduct Disorder
Interventions: BEHAVIORAL: PRE-Venture: Personality Risk Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ipilimumab With Lymphodepletion Plus Adoptive Cell Transfer and High Dose IL-2 in Melanoma Mets Pts
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Melanoma
Interventions: DRUG: Ipilimumab|PROCEDURE: Tumor Infiltrating Lymphocytes (TIL)|DRUG: Administration of Lymphodepletion|DRUG: Cyclophosphamide as Part of Lymphodepletion|DRUG: Fludarabine as Part of Lymphodepletion|DRUG: High Dose IL-2|BIOLOGICAL: Adoptive Cell Therapy with TIL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TCM Syndrome Differentiation Treatment on Discharged Elderly Patients With CAP
Status: UNKNOWN
Conditions: Community-acquired Pneumonia
Interventions: DRUG: Traditional Chinese medicine granules|DRUG: Traditional Chinese medicine granules placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Placebo and Active Comparator Controlled Dose Response Study of Rivoglitazone in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Rivoglitazone HCl|DRUG: rivoglitazone HCl|DRUG: rivoglitazone HCl|DRUG: pioglitazone HCl|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Lactococcus Lactis Probiotic Bacteria for the Treatment of Chronic Rhinosinusitis
Status: COMPLETED
Conditions: Chronic Rhinosinusitis
Interventions: OTHER: Topical probiotic treatment with Lactococcus lactis W136|OTHER: Saline irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Extract of Gelidium Elegans
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Exract of Gelidium elegans|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Celecoxib in Postoperative Analgesia for Radius Fracture Surgery
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Celecoxib 100 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Actis Total Hip System 2 Year Follow-up
Status: COMPLETED
Conditions: Osteoarthritis|Traumatic Arthritis|Rheumatoid Arthritis|Congenital Hip Dysplasia|Avascular Necrosis of the Femoral Head|Acute Traumatic Fracture of the Femoral Head or Neck|Certain Cases of Ankylosis|Non-union of Femoral Neck Fractures|Certain High Sub-Capital & Femoral Neck Fractures in Elderly
Interventions: DEVICE: Actis Total Hip System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cadonilimab (PD-1/CTLA-4 Bi-specific Antibody) and Chemoradiotherapy in Locoregionally-advanced Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma|Nasopharyngeal Cancer
Interventions: DRUG: Cadonilimab|DRUG: Gemcitabine|DRUG: Cisplatin|RADIATION: Intensity-modulated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of 1 Cycle of Adjuvant BEP Chemotherapy in High Risk, Stage 1 Non-seminomatous Germ Cell Testis Tumours
Status: UNKNOWN
Conditions: Stage I Testicular Non-Seminomatous Germ Cell Tumor
Interventions: DRUG: BEP(500)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Confirm the Safety and Efficacy of CJ-12420 in Patients With Erosive Esophagitis
Status: COMPLETED
Conditions: Erosive Esophagitis
Interventions: DRUG: CJ-12420 100mg QD|DRUG: Esomeprazole 40mg|DRUG: CJ-12420 50mg QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of Antioxidants Astaxanthin as an Adjuvant Therapy for Community Acquired Pneumonia Patients.
Status: RECRUITING
Conditions: Community-acquired Pneumonia
Interventions: DRUG: Astaxanthin Oral Capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of KRX-0502 (Ferric Citrate, Administered Without Food, in Treating Iron-deficiency Anemia
Status: COMPLETED
Conditions: Anemia of Chronic Kidney Disease
Interventions: DRUG: KRX-0502
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combining Noninvasive Brain Stimulation and Cognitive Training on Tobacco Craving
Status: UNKNOWN
Conditions: Tobacco Use Disorder
Interventions: BEHAVIORAL: Cognitive training|DEVICE: Noninvasive brain stimulation (active)|DEVICE: Noninvasive brain stimulation (sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 3 Study of Pembrolizumab + Epacadostat or Placebo in Subjects With Unresectable or Metastatic Melanoma (Keynote-252 / ECHO-301)
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: pembrolizumab + epacadostat|DRUG: pembrolizumab + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thol'Impilo: Bringing People Into Care
Status: COMPLETED
Conditions: HIV
Interventions: OTHER: Point of care CD4 testing|BEHAVIORAL: Care Facilitation|OTHER: Transport support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Controlled-Release Oxycodone For Postoperative Analgesia After Video-Assisted Thoracic Surgery
Status: TERMINATED
Conditions: Anesthesia Recovery Period|Pain, Postoperative
Interventions: DRUG: Morphine|DRUG: oxycodone|PROCEDURE: Paravertebral block|DRUG: Propofol|DRUG: Remifentanil|DRUG: Paracetamol|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SUPER Study; SUPERvised Exercise or Angioplasty for Intermittent Claudication Due to an Iliac Artery Obstruction.
Status: TERMINATED
Conditions: Intermittent Claudication|Peripheral Arterial Disease
Interventions: PROCEDURE: Percutaneous Transluminal Angioplasty|OTHER: Supervised Exercise Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigator Initiated Study to Assess the Efficacy of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease Following Laser-assisted in Situ Keratomileusis (LASIK)
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: OC-01 (varenicline 0.6mg/ml) nasal spray|DRUG: Placebo (vehicle) nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Marketing Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of Ipragliflozin in Combination With GLP-1 Receptor Agonists in Japanese Patients With Type 2 Diabetes Mellitus (T2DM)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Ipragliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiopulmonary Adaptation of Short Term Exposure to High Altitude in Fontan Patients: Swiss Fontan & ALtitude COllaboratioN (FALCON) Study
Status: COMPLETED
Conditions: Fontan Procedure|Altitude
Interventions: OTHER: High altitude exposition
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: BL-B01D1|DRUG: Irinotecan|DRUG: paclitaxel|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Intravenous Lipotecan® (TLC388 HCl for Injection) in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: Lipotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CellMist™ Autologous Cells to Treat Deep Second-Degree Burns
Status: UNKNOWN
Conditions: Burns|Burns Second Degree|Burns Deep Second Degree
Interventions: DEVICE: CellMist™ System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety,Tolerability,and Pharmacokinetics of Multiple-Ascending Dose JS1-1-01 in Healty Subjects.
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: JS1-1-01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Apremilast to Treat Subjects With Active Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondyloarthritis
Interventions: DRUG: Apremilast tablet 20 mg|DRUG: Apremilast tablet 30 mg BID|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Acupuncture in Prevention of Chemotherapy Induced Peripheral Neuropathy - a Pilot Study
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: OTHER: Verum acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Nicotinic Cholinergic System and Cognitive Aging
Status: COMPLETED
Conditions: Healthy Aging
Interventions: DRUG: Nicotine patch, oral mecamylamine, placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Apalutamide in Participants With Severe Hepatic Impairment Compared With Participants With Normal Hepatic Function
Status: RECRUITING
Conditions: Hepatic Impairment
Interventions: DRUG: Apalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NUTRACORE, Glycaemic Index and Appetite
Status: COMPLETED
Conditions: Hyperglycemia|Hyperglycemia, Postprandial|Appetitive Behavior|Hyperinsulinism|Consumer Preference
Interventions: DIETARY_SUPPLEMENT: Same intervention for both groups: glycaemic index assessment of 3 biscuits recipes|DIETARY_SUPPLEMENT: Crossover: Recipe 4 before recipe 5|DIETARY_SUPPLEMENT: Crossover: Recipe 5 before recipe 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Right Ventricular Septal Pacing for the Prevention of Left Ventricular Dysfunction in Patients With Atrio-Ventricular Block
Status: UNKNOWN
Conditions: Atrio-Ventricular Block
Interventions: DEVICE: Pacemaker Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Food Intake and Drug-drug Interactions of E7090 When Co-administered With Rabeprazole or Rifampin in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: E7090|DRUG: Rabeprazole 20 mg|DRUG: Rifampin 600 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DORADO-EX: Long-Term Safety Extension Study to the Phase 3 DORADO Study (Protocol DAR-311) of Darusentan in Resistant Hypertension
Status: TERMINATED
Conditions: Hypertension
Interventions: DRUG: Darusentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Nystatin Prophylaxis to Prevent Systemic Fungal Infection in Very Low Birth Weight Preterm Infants
Status: COMPLETED
Conditions: Fungal Infections Systemic
Interventions: DRUG: Nystatin Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigation of Compliance With Ventilator-Associated Pneumonia Prevention Methods and Incidence of Ventilator-Associated Pneumonia in Intensive Care Units
Status: UNKNOWN
Conditions: The Incidence of Ventilator-associated Pneumonia and Rate of Compliance With Survey Criteria
Interventions: OTHER: ventilator-associated pneumonia-developed group followed by mechanical ventilation|OTHER: not ventilator-associated pneumonia-developed group followed by mechanical ventilation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of Tapentadol Oral Solution for Pain After Surgery in Children From Newborn to Less Than 2 Years Old
Status: TERMINATED
Conditions: Moderate to Severe Acute Postoperative Pain
Interventions: DRUG: Tapentadol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Norditropin NordiFlex® Device Compared to the Device Previously Used by Patients or Parents
Status: COMPLETED
Conditions: Growth Hormone Disorder|Growth Hormone Deficiency in Children|Foetal Growth Problem|Small for Gestational Age|Genetic Disorder|Turner Syndrome|Chronic Kidney Disease|Chronic Renal Insufficiency|Delivery Systems
Interventions: DEVICE: Norditropin NordiFlex®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Implants Placed in Consolidated Graft With Different Bone Drills.
Status: RECRUITING
Conditions: Implant Complication|Bone Graft; Mechanical Complications
Interventions: PROCEDURE: Dental implants placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sympathetic Dysfunction on Muscle Spindle in Fibromyalgia
Status: NOT_YET_RECRUITING
Conditions: Fibromyalgia
Interventions: DIAGNOSTIC_TEST: sympathetic stimulation maneuver (mental arithmetic test, cold pressure test)|DRUG: Pregabalin 150mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: B-cell Chronic Lymphoid Malignancies Markers
Status: UNKNOWN
Conditions: Chronic Lymphocytic Leukemia|Marginal Zone Lymphoma|Lymphoplasmacytic Lymphoma/Waldenström Macroglobulinemia|Mantle Cell Lymphoma|Hairy Cell Leukemia|Follicular Lymphoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Global Study of MK-2060 (Anti-Factor XI Monoclonal Antibody) in Participants With End Stage Renal Disease Receiving Hemodialysis (FXI Hemodialysis Study) (MK-2060-007)
Status: ACTIVE_NOT_RECRUITING
Conditions: End-Stage Renal Disease|End-Stage Kidney Disease|Kidney Failure, Chronic
Interventions: DRUG: MK-2060|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Essure® Micro-inserts in Women With Hydrosalpinx Prior to In Vitro Fertilization: A Prospective, Multicenter, International Feasibility Study
Status: COMPLETED
Conditions: Women Who Suffer From Hydrosalpinx That is Causing Infertility and Whom Want a Safer Way of Treamtent
Interventions: DEVICE: Essure Micro Insert
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: RCT of Progesterone to Prevent Preterm Birth in Nulliparous Women With a Short Cervix
Status: TERMINATED
Conditions: Preterm Delivery|Cervical Length
Interventions: DRUG: 17 alpha-hydroxyprogesterone caproate|OTHER: Placebo Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Adult Pulmonary Langerhans Cell Histiocytosis: a National Registry-based Prospective Cohort Study
Status: RECRUITING
Conditions: Histiocytosis|Histiocytosis, Langerhans-Cell|Histiocytosis Pulmonary
Interventions: OTHER: Standard of care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Pulsatile Gonadotropin Releasing Hormone Pump Treatment in Patients With Idiopathic Hypogonadotropic Hypogonadism
Status: UNKNOWN
Conditions: Idiopathic Hypogonadotropic Hypogonadism
Interventions: DRUG: Pulsatile Gonadotropin Releasing Hormone|DRUG: Human chorionic gonadotropin|DRUG: Urinary Follicle-Stimulating Hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trauma Acute Pain Treatment With Methoxyflurane Vaporized (PENTHROX®): Efficacy and Safety Study (MEDITA)
Status: COMPLETED
Conditions: Acute Traumatic Pain
Interventions: COMBINATION_PRODUCT: Methoxyflurane and Penthrox inhaler|DRUG: Morphine|DRUG: Paracetamol|DRUG: Ketoprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin, Fludarabine, Cytarabine and Rituximab in Richter's Syndrome, Refractory CLL and PLL
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Cytarabine|DRUG: Fludarabine|DRUG: Oxaliplatin|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-term Extension Study of TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis(ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: TCH346
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Seroquel in Acute Mania: Study to Investigate if Valproate Add-On Therapy is Superior to Quetiapine Monotherapy in Acutely Manic Patients
Status: TERMINATED
Conditions: Bipolar Disorder
Interventions: DRUG: Quetiapine fumarate|DRUG: sodium valproate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Substance Use Interventions for Truant Adolescents
Status: COMPLETED
Conditions: Adolescent Problem Behavior|Truancy; Unsocialized|Marijuana Abuse|Truancy; Socialized|Substance Abuse|Alcohol Abuse
Interventions: BEHAVIORAL: Motivational + Family Check-up (MET+FCU)|OTHER: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Project AdaPT: An Adaptive Physiotherapy Intervention Augmented With a Healthy Mind Training Program for People With Chronic Low Back Pain
Status: COMPLETED
Conditions: Back Pain Lower Back Chronic|Disability Physical
Interventions: BEHAVIORAL: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cocoa Flavanols on Vascular Function
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DIETARY_SUPPLEMENT: Cocoa Flavanols|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Povidone-Iodine Versus Chlorhexidine Gluconate Solutions in Reducing Microbial Contamination in Spinal Surgery Wounds During Intraoperative Soaking.
Status: RECRUITING
Conditions: Spine Infection
Interventions: DRUG: Povidone-iodine solution; chlorhexidine gluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Hypertonic Saline and Mannitol on Brain Relaxation During Supratentorial Tumors Resection
Status: UNKNOWN
Conditions: Brain Tumor - Metastatic|Brain Tumor, Adult: Glioblastoma
Interventions: DRUG: %3 HS bolus|DRUG: %3 HS infusion 20 ml/h|DRUG: 20% mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SPYRAL AFFIRM Global Study of RDN with the Symplicity Spyral RDN System in Subjects with Uncontrolled HTN
Status: RECRUITING
Conditions: Hypertension|Vascular Diseases|Cardiovascular Diseases|Chronic Kidney Diseases|Diabetes Mellitus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apatinib Combined With POF for Second-line Treatment of Gastric Adenocarcinoma
Status: UNKNOWN
Conditions: Gastric Adenocarcinoma
Interventions: DRUG: Apatinib|DRUG: POF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tadalafil Effect + Chemotherapy in Resectable Gastric/GEJ Cancer
Status: RECRUITING
Conditions: Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Tadalafil 20 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Brexpiprazole Orally Disintegrating Tablets (ODT) 2mg
Status: COMPLETED
Conditions: Healthy Adult Male
Interventions: DRUG: Brexpiprazole ODT 2mg with water|DRUG: Brexpiprazole ODT 2mg without water|DRUG: Brexpiprazole conventional tablet 2mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic Administartion to Mothers of Preterm Infants to Prevent Necrotizing Enterocolitis and Sepsis
Status: TERMINATED
Conditions: Necrotizing Enterocolitis|Sepsis
Interventions: DRUG: Probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hypofractionated Radiation Therapy for Patients With Breast Cancer Receiving Regional Nodal Irradiation
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: Hypofractionated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Economic Impact of Guidelines for Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease|Health Economics
Interventions: DRUG: Disease management of gastroesophageal reflux disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Pericapsular Nerve Group Block vs Interscalene Block for Shoulder Arthroscopy
Status: RECRUITING
Conditions: Anesthesia|Regional Anesthesia Morbidity|Shoulder Pain|Arthroscopy
Interventions: PROCEDURE: Ultrasound-guided PENG or ISBP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exubera vs Lispro in a Lantus-based Regimen for Improved Glycemic Control in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Insulin Lispro|DRUG: Exubera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alcohol and Tobacco Consumption in Patients With Head and Neck or Lung Cancer : Interest of an Addiction Treatment
Status: COMPLETED
Conditions: Upper Aerodigestive Tract Neoplasms|Lung Cancer
Interventions: PROCEDURE: integrated addiction treatment program|PROCEDURE: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy (Induction of Response/Remission) and Safety Study in Patients With Moderate to Severe Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: DRUG: Sargramostim (Leukine)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Concurrent C225, Cisplatin and Radiation in Stage IV Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: cetuximab C225|DRUG: cisplatin|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Efficacy and Safety of HH-003 Injection in Subjects With Chronic Hepatitis Delta Virus Infection
Status: RECRUITING
Conditions: Chronic Hepatitis Delta Virus Infection
Interventions: BIOLOGICAL: HH-003(20mg/kg)|BIOLOGICAL: HH-003(10mg/kg)|DRUG: TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Meditation and Insomnia in Alzheimer Disease Caregivers
Status: COMPLETED
Conditions: Insomnia Chronic
Interventions: BEHAVIORAL: CBT-I|BEHAVIORAL: MAP-I
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Routine Pregnancy Screening for Women on Opioid Substitution Therapy
Status: TERMINATED
Conditions: Substance Use Disorders|Prenatal Care|Pregnancy Outcome
Interventions: OTHER: Monthly Pregnancy Screening|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Assessment of the Interest of the Atalante Device for Patients With Manual Wheelchairs
Status: COMPLETED
Conditions: Complete Motor Paraplegia
Interventions: DEVICE: Test with Atalante exoskeleton in "continuous walk" type
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Trial of Vitamin D Supplementation for the Prevention of Influenza and Other Respiratory Infections (ViDiFlu)
Status: COMPLETED
Conditions: Respiratory Tract Infections|Influenza
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol (Vitamin D/Vigantol oil)|DIETARY_SUPPLEMENT: Miglyol oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dose-response Effect of Dietary Nitrate on Muscle Function in Older Individuals
Status: COMPLETED
Conditions: Aging|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Beet root juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Shockwave on Abdominal Adiposity and Lipid Profile
Status: COMPLETED
Conditions: Obesity, Abdominal
Interventions: OTHER: Extracorporeal Shockwave therapy|OTHER: Balanced low-calorie diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostics for the Treatment of Progressive Mucosal Lesions of the Oral Cavity: a Prospective Study
Status: WITHDRAWN
Conditions: Chromosomal Instability|Low Grade Dysplasia Oral Cavity|Loss of Heterozygostiy|Fluorescence In Situ Hybridization
Interventions: PROCEDURE: surgery|OTHER: follow up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of the Investigational GSK Biologicals' GSK3277511A Vaccine in Adults.
Status: COMPLETED
Conditions: Respiratory Disorders
Interventions: BIOLOGICAL: Formulation 1 (plain): NTHi/Mcat vaccine GSK3277513A|BIOLOGICAL: Formulation 2 (adjuvanted): NTHi/Mcat vaccine GSK3277513A|BIOLOGICAL: Formulation 3 (adjuvanted): NTHi/Mcat vaccine GSK3339036A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: HEC73543 Versus Salvage Chemotherapy in R/R FLT3-ITD AML
Status: RECRUITING
Conditions: Leukemia, Acute Myeloid (AML)
Interventions: DRUG: Clifutinib|DRUG: LoDAC|DRUG: Azacitidine|DRUG: Decitabine|DRUG: Ara-C±IDA|DRUG: FLAG-IDA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Approach to Radiotherapy in Locally Advanced Lung Cancer Concomitant Navelbine®
Status: RECRUITING
Conditions: NSCLC
Interventions: RADIATION: Escalated: Inhomogeneous dose plan|RADIATION: Standard: Homogeneous dose plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Tranexamic Acid in Reducing Blood Loss During Cytoreductive Surgery and HIPEC
Status: COMPLETED
Conditions: Cytoreductive Surgery
Interventions: DRUG: tranexamic Acid infusion|DRUG: saline infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effect of Terlipressin on Cerebral Oxygen Saturation During Liver Transplantation
Status: COMPLETED
Conditions: Terlipressin Adverse Reaction|Liver Transplantation
Interventions: DRUG: Terlipressin|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ivosidenib + mFOLFIRINOX in Patients With Resectable Pancreatic Adenocarcinoma
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma|Resectable Pancreatic Cancer
Interventions: DRUG: Ivosidenib|DRUG: mFOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Occipital Blocks for Acute Migraine
Status: COMPLETED
Conditions: Chronic Migraine, Headache|Episodic Migraine
Interventions: DRUG: Lidocaine 4% Topical Application Cream [LMX 4]|DRUG: Lidocaine Hydrochloride 2 mg/mL Injectable Solution|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Observational Trial to Evaluate Quality of Life After Neoadjuvant or Definitive Chemoradiation in Patients With Esophageal Cancer
Status: RECRUITING
Conditions: Quality of Life|Chemoradiation|Esophageal Cancer
Interventions: OTHER: EORTC QLQ C30|OTHER: EORTC QLQ OES-18|OTHER: EORTC OG-25
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose Escalation Study of Nelfinavir Plus MLN9708 in Patients With Advanced Solid Tumors or Lymphoma
Status: WITHDRAWN
Conditions: Neoplasms|Lymphoma
Interventions: DRUG: MLN9708|DRUG: Nelfinavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of the Gut Sweet Taste Receptor in the Secretion of Satiation Peptides
Status: COMPLETED
Conditions: Taste Disorder, Secondary, Sweet
Interventions: DIETARY_SUPPLEMENT: lactisole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Bile Acids on Satiety, Cell Function and Body Weight in Patients With Obesity and Abnormal Satiety Phenotype
Status: ENROLLING_BY_INVITATION
Conditions: Obesity|Healthy
Interventions: DIETARY_SUPPLEMENT: Ileocolonic-release conjugated bile acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Nutritional Supplement Effect on HDL Function
Status: COMPLETED
Conditions: HDL
Interventions: DIETARY_SUPPLEMENT: CardioLux™HDL|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Epidural Anesthesia /Analgesia Versus PCA for Laparoscopic Complex Ventral Hernia Repair: A Randomized Controlled Trial
Status: WITHDRAWN
Conditions: Analgesia
Interventions: DEVICE: Epidural Catheter for Analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT