pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intramyocardial Haemorrhage in Patients With Primary STEMI
Status: COMPLETED
Conditions: Myocardial Infarction|STEMI|Myocardial Necrosis|Myocardial Injury
Interventions: DRUG: Pharmaco-invasive strategy|PROCEDURE: Primary PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 1 Study to Compare the Safety, Pharmacokinetic Profiles of CJ-30056 and Lipitor/Glucophage XR
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Atorvastatin 20mg and Metformin XR 500mg (Reference)|DRUG: CJ-30056 20/500mg (Test)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two Recovery Strategies at Work, Based on Mindfulness and Physical Exercise, on Levels of Stress and Biological Measures
Status: WITHDRAWN
Conditions: Mental Health Wellness
Interventions: BEHAVIORAL: Mindfulness-based intervention|BEHAVIORAL: Physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Finding Study of CC-96673 in Participants With Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: CC-96673
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Low-Dose Cyclophosphamide in Treating Patients With Recurrent Ovarian Epithelial or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Primary Peritoneal Carcinoma|Recurrent Ovarian Carcinoma|Stage IV Ovarian Cancer
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Cyclophosphamide|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 0.05% CsA and 0.1% FK506 Eye Drops in Ocular GVHD Treatment
Status: COMPLETED
Conditions: Graft Versus Host Disease in Eye
Interventions: DRUG: Cyclosporine|DRUG: tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetic, and Efficacy Study of SPD489 in Preschool Children With Attention-deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: DRUG: SPD489
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Arrhythmias and Sudden Death in Patients Affected With Laminopathies
Status: UNKNOWN
Conditions: Cardiomyopathy Associated With Myopathy and Sudden Death
Interventions: DEVICE: Electrophysiological Study and ECG holter monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study Assessing the Safety and Tolerability of LY03020 in Chinese Healthy Subjects
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia|Alzheimer's Disease Psychosis
Interventions: DRUG: LY03020|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect on Pain Control of Treatment With Fentanyl, Administered Through the Skin, Compared With Placebo in Patients With Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis|Arthritis
Interventions: DRUG: fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Impact of Immunosuppressive Regimens on Polyomavirus-related Transplant Nephropathy
Status: COMPLETED
Conditions: Polyomavirus Infections
Interventions: DRUG: Ciclosporin and Mycophenolate-mofetil|DRUG: Tacrolimus and Mycophenolate-mofetil|DRUG: Tacrolimus and Mycophenolate-mofetil with change from Mycophenolate-mofetil to Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation in Different Doses on Strength Capacities and Functional Performance
Status: COMPLETED
Conditions: Low Level Laser Therapy|Performance|Sport
Interventions: OTHER: Photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Ibuprofen and Pseudoephedrine Comparative Pharmacokinetic Study
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Test Nurofen Cold and Flu®, Ibuprofen and pseudoephedrine liquid capsules|DRUG: Comparator 1 Nurofen Cold and Flu®, ibuprofen and pseudoephedrine tablets|DRUG: Comparator 2 Nurofen Immedia 200 mg Weichkapseln, ibuprofen liquid capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Partners for Better Health in Adolescent Type 2 Diabetes: The Buddy Study
Status: COMPLETED
Conditions: Obesity|Diabetes Mellitus, Type 2|Abnormal Glucose Metabolism|Type 2 Diabetes
Interventions: BEHAVIORAL: Assignment of a Lay Patient Partner
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Severe Influenza A Infection
Status: COMPLETED
Conditions: Influenza, Human
Interventions: DRUG: Celecoxib|DRUG: Oseltamivir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New Treatment for Alcohol and Nicotine Dependence
Status: UNKNOWN
Conditions: Alcohol Dependence|Nicotine Dependence
Interventions: DRUG: Topiramate with brief behavioral enhancement therapy|DRUG: Placebo with brief behavioral enhancement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laser Vaginal Treatment for GSM
Status: RECRUITING
Conditions: Menopausal Urethral Atrophy|Vulvar Atrophy
Interventions: PROCEDURE: laser vaginal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Bendamustine in Combination With Ofatumumab, Carboplatin and Etoposide
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Bendamustine|DRUG: Ofatumumab|DRUG: Carboplatin|DRUG: Etoposide|PROCEDURE: CT Scan|PROCEDURE: PET Scan|GENETIC: Stem Cell Transplant (STC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phone Breastfeeding Support for Premature Babies
Status: UNKNOWN
Conditions: Preterm Birth|Breastfeeding
Interventions: BEHAVIORAL: Telephone Breastfeeding Support Program|BEHAVIORAL: Sending a breastfeeding guide for premature babies to the phone of mothers in addition to the routine discharge procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Study of PEG-Paclitaxel In Patients With Advanced Solid Tumors & Lymphomas
Status: TERMINATED
Conditions: Neoplasm|Lymphomas|Neoplasm Metastasis
Interventions: DRUG: PEG-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Efficacy Study of CombiflexOmega Versus SmofKabiven in Patients With Parenteral Nutrition
Status: COMPLETED
Conditions: Parent
Interventions: DRUG: CombiflexOmega|DRUG: SmofKabiven
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Versus Triamcinolone Treatment in Carpal Tunnel Syndrome
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: Dexmedetomidine|DRUG: Triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Digital Therapeutic to Improve Insomnia in Multiple Sclerosis: A Randomized Controlled Trial.
Status: RECRUITING
Conditions: Multiple Sclerosis|Insomnia
Interventions: BEHAVIORAL: Digital Cognitive Behavioral Therapy for Insomnia (dCBT-I)|BEHAVIORAL: Digital patient education about insomnia (PE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial for Treatment of Aromatic L-amino Acid Decarboxylase (AADC) Deficiency Using AAV2-hAADC - An Expansion
Status: COMPLETED
Conditions: Aromatic Amino Acid Decarboxylase Deficiency
Interventions: DRUG: AAV2-hAADC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Oral L-Arginine on Chronic Hypertension in Pregnancy
Status: COMPLETED
Conditions: Hypertension in Pregnancy
Interventions: DRUG: L-Arginine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of TRO19622 as add-on Therapy to Riluzole Versus Placebo in Treatment of Patients Suffering From ALS
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Olesoxime|DRUG: Placebo Comparator|DRUG: Riluzole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Young Adults With Life Threatening Cow's Milk Allergy: Risks of Decrease Bone Mineralization and Methods of Calcium Supplementation
Status: UNKNOWN
Conditions: Bone Mineral Density in Cow's Milk Allergic Patients
Interventions: DIETARY_SUPPLEMENT: Experimental|BEHAVIORAL: Active comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Promoting Self Care to Prevent Urinary Incontinence (UI): A Four-Year Follow-up
Status: COMPLETED
Conditions: Urinary Incontinence|Bladder Control
Interventions: BEHAVIORAL: Bladder Health Class consisting of 6 weekly group sessions|BEHAVIORAL: Practice PFMT and BT|BEHAVIORAL: Clinic examination for pelvic muscle function|BEHAVIORAL: Record keeping in 3-day voiding diary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: M-PART in Head and Neck Cancer Patients Treated With KeraStat Cream for Acute Radiation Dermatitis
Status: NOT_YET_RECRUITING
Conditions: Radiation Dermatitis
Interventions: DEVICE: KeraStat cream|DEVICE: M-PART Assessments via MyCap|OTHER: Clinical Assessments|OTHER: Feedback phone interview
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study in Healthy Participants to Assess the Pharmacokinetics and Safety of a Supratherapeutic Dose of PCI-32765 (Ibrutinib) Capsule and Solution Formulations Administered With Food
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Treatment A: PCI-32765|DRUG: Treatment B: PCI-32765
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GSK2982772 Study in Subjects With Ulcerative Colitis
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: DRUG: GSK2982772|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis (LIMBER-313)
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelofibrosis|Primary Myelofibrosis|Post Essential Thrombocythemia Myelofibrosis|Post Polycythemia Vera Myelofibrosis
Interventions: DRUG: parsaclisib|DRUG: ruxolitinib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Arm, Prospective, Multicenter Clinical Study of TACE With Adebrelimab and Bevacizumab for Unresectable Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Adebrelimab|Hepatocellular Carcinoma|Transformation|Bevacizumab|TACE
Interventions: DRUG: TACE with adebrelimab and bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of WBV in Children With Hemiparetic CP
Status: COMPLETED
Conditions: Cerebral Palsy|Whole Body Vibration|Spastic Hemiplegia|Motor Performance
Interventions: OTHER: Whole-Body Vibration|OTHER: Conventional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Calcineurin Inhibitor-Sparing Immunosuppression Regimen in Pediatric Liver Transplantation
Status: TERMINATED
Conditions: End-stage Liver Disease|Renal Insufficiency|Renal Failure
Interventions: DRUG: mycophenolate mofetil|OTHER: placebo medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assess the Oral Bioavailability of a New ABT-263 Formulation in Subjects With Cancer
Status: COMPLETED
Conditions: Lymphoid Malignancy|Solid Tumors
Interventions: DRUG: ABT-263|DRUG: ABT-263|DRUG: ABT-263|DRUG: ABT-263
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bifidobacterium Animalis Subsp. Lactis for Lowering the Risk of Common Infections in Hospitalized Children
Status: COMPLETED
Conditions: Gastrointestinal Tract Infections|Respiratory Tract Infections
Interventions: DIETARY_SUPPLEMENT: Bifidobacterium animalis subsp. lactis
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: Study on the Efficacy and Safety of Low-dose CTX as Maintenance Therapy for MM Unsuitable for Transplantation
Status: RECRUITING
Conditions: Newly Diagnosed Multiple Myeloma
Interventions: DRUG: Cyclophosphamide|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Medical Research Study to Evaluate the Effects of ACT-246475 in Adults With Coronary Artery Disease
Status: COMPLETED
Conditions: Stable Coronary Artery Disease
Interventions: DRUG: Selatogrel|DRUG: Placebo|DRUG: Selatogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic Drug Interaction Between Cilostazol and Statins
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cilostazol|DRUG: Simvastatin|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Japanese Phase 1 Study of GSK2585823
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: GSK2585823|DRUG: Benzoyl peroxide 3%|DRUG: Benzoyl peroxide 5%|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Meditation and Opioid Consumption in Total Joint Replacement Patients Undergo Primary Total Hip and Knee Replacement
Status: COMPLETED
Conditions: Arthropathy of Knee|Osteo Arthritis Knee|Osteonecrosis|Meditation|Knee Osteoarthritis|Knee Disease|Knee Injuries|Opioid Use|Opioid Dependence|Opioid Use Disorder
Interventions: BEHAVIORAL: Mindful meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Tourniquet Use on Physical Function and Performance in Primary Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Non-tourniquet assisted TKA|PROCEDURE: Tourniquet assisted TKA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Natural Progesterone for the Treatment of Recurrent Glioblastoma
Status: RECRUITING
Conditions: Gliosarcoma|Recurrent Glioblastoma
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|BIOLOGICAL: Therapeutic Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of 72-hour and 120-hour Infusion of Rigosertib in Acute Myeloid Leukemia (AML) and Acute Lymphoid Leukemia (ALL)
Status: COMPLETED
Conditions: Acute Myelocytic Leukemia|Acute Lymphocytic Leukemia|Myeloproliferative Disease|Chronic Myeloid Leukemia
Interventions: DRUG: rigosertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Pilot Study of Newly Developed Ostomy Tapes and How They Adhere to the Skin
Status: COMPLETED
Conditions: Stoma Site Leakage
Interventions: DEVICE: Test product A|DEVICE: Test product B|DEVICE: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of Probiotics for the Therapy of Acute Pharyngotonsillitis in Adult Patients
Status: COMPLETED
Conditions: Throat Pain
Interventions: DRUG: Placebo|DRUG: Probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Function/Fitness and Psychosocial Health in Improving Health-Related Quality of Life in Patients With Stage I-IV Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Smoking|Lung Neoplasms
Interventions: OTHER: Integrated Fitness Assessment|PROCEDURE: Psychosocial Assessment and Care|PROCEDURE: Quality-of-Life Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rezvilutamide in Patients With Biochemical Recurrence After Radical Prostatectomy for Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Biochemical Recurrence
Interventions: DRUG: Rezvilutamide|DRUG: Androgen deprivation therapy (ADT)|RADIATION: SRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Linagliptin Inpatient Trial
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Linagliptin|DRUG: Basal Bolus|DRUG: Linagliptin|DRUG: Linagliptin + 50% Glargine dose on discharge|DRUG: Linagliptin + 80% Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S1200: Acupuncture, Sham Acupuncture, or Wait List for Joint Symptoms Related to Aromatase Inhibitors in Pts W/Early-Stage Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Pain
Interventions: PROCEDURE: acupuncture therapy|PROCEDURE: sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Investigational Immuno-therapy Study of Nivolumab, or Nivolumab in Combination With Ipilimumab, or Placebo in Patients With Extensive-Stage Disease Small Cell Lung Cancer (ED-SCLC) After Completion of Platinum-based Chemotherapy
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Seminal Plasma Insemination on Pregnancy Rates After IVF-ET
Status: COMPLETED
Conditions: Effect on Implantation and Pregnancy Rates
Interventions: PROCEDURE: seminal plasma insemination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Elastography of the Liver in Cystic Fibrosis Patients. Diagnostic and Prognostic Aspects
Status: COMPLETED
Conditions: Cystic Fibrosis|Liver Fibrosis
Interventions: DEVICE: Fibroscan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Gabapentin to Improve Patient Tolerance in Endoscopic Retrograde Cholangiopancreatography (ERCP)
Status: COMPLETED
Conditions: Conscious Sedation
Interventions: DRUG: Gabapentin|OTHER: Standard sedation regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aromatherapy With Lavender as Anxiolysis Prior to Cataracts Surgery
Status: WITHDRAWN
Conditions: Aromatherapy|Anxiety
Interventions: OTHER: Lavender Aromatherapy|OTHER: Non-scented Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Coenzyme Q10 and Clomiphene Citrate (CC) for Ovulation Induction in Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Coenzyme Q10|DRUG: clomiphene citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Evaluation of Kefir Drink on Antifatigue and Exercise Exercise Performance-2
Status: COMPLETED
Conditions: Exercise Performance|Fatigue
Interventions: DIETARY_SUPPLEMENT: Kefir|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Vitamin D as an add-on Therapy With Pegylated Interferon and Ribavirin for Chronic Hepatitis c
Status: UNKNOWN
Conditions: Chronic Hepatitis c
Interventions: DRUG: vitamin D +pegylated interferon + ribavirin|DRUG: pegylated interferon + ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Supplementation to Enhance Recovery Pilot Study
Status: COMPLETED
Conditions: Malignant Neoplasms of Urinary Tract
Interventions: DRUG: Arginine recovery supplement|DIETARY_SUPPLEMENT: Omega-3 Fatty Acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pilot Study of Evidence-based Guided Self-help for the Treatment of Binge Eating
Status: RECRUITING
Conditions: Binge-Eating Disorder|Binge Eating
Interventions: BEHAVIORAL: Cognitive behavioral therapy guided self help (CBTgsh)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: First-line Treatment of PCNSL With the Combination of Orelabrutinib, Rituximab, and Methotrexate (ORM Regimen)
Status: COMPLETED
Conditions: Primary Central Nervous System Lymphoma
Interventions: DRUG: ORM regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of TV-1380 as Treatment for Facilitation of Abstinence in Cocaine-Dependent Subjects
Status: COMPLETED
Conditions: Cocaine Addiction
Interventions: DRUG: TV-1380 150 mg|DRUG: TV-1380 300 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Horizontal Augmentation With Deproteinized Bovine Bone Mineral Alone or in Combination With Particulate Autogenous Bone
Status: ACTIVE_NOT_RECRUITING
Conditions: Edentulous Jaw
Interventions: PROCEDURE: Lateral ridge augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BIOCLEAN FIRST CARE EX in Combination With Biofinity Lens
Status: COMPLETED
Conditions: Myopia
Interventions: OTHER: Bioclean First Care EX / comfilcon A|OTHER: Aosept Clearcare / comfilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Bisoprolol Administration to Prevent Anthracycline-induced Cardiotoxicity
Status: COMPLETED
Conditions: Cardiomyopathies|Chemotherapy Effect|Diastolic Dysfunction|Systolic Dysfunction
Interventions: DRUG: Bisoprolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Botox or Botox With Esophageal Dilation in Patients With Achalasia
Status: ENROLLING_BY_INVITATION
Conditions: Achalasia
Interventions: DRUG: Botulinum toxin type A|DEVICE: Endoscope balloon dilator|OTHER: Patient reported outcomes|DIAGNOSTIC_TEST: Barium esophagram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ASSURE WCD Clinical Evaluation - Conversion Efficacy Study
Status: COMPLETED
Conditions: Death, Sudden, Cardiac
Interventions: DEVICE: Defibrillation using the ASSURE wearable cardioverter defibrillator therapy delivered via a waveform delivery test system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Simple Perioperative Measures Improve Quality of Recovery Following Ambulatory Laparoscopic Surgery in Females?
Status: COMPLETED
Conditions: Quality of Recovery
Interventions: OTHER: ProvideXtra® Fresenius Kabi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Valproic Acid and Carnitine in Patients With Spinal Muscular Atrophy
Status: COMPLETED
Conditions: Spinal Muscular Atrophy
Interventions: DRUG: Valproic Acid and Levocarnitine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Phase II Study to Compare the Potential Long-Lasting Positive Effect of Decidual Stromal Cells to the Best Available Treatment in Graft Versus Host Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Graft Vs Host Disease
Interventions: OTHER: Drug or biologic - anti-thymocyte globulin (ATG), extracorporeal photopheresis (ECP), mTOR inhibitors (everolimus or sirolimus), vedolizumab, ruxolitinib.|BIOLOGICAL: Decidual Stromal Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesothelin-Specific T-Cells (FH-TCR-Tᴍsʟɴ) for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma
Status: RECRUITING
Conditions: Metastatic Pancreatic Ductal Adenocarcinoma|Stage IV Pancreatic Cancer AJCC v8
Interventions: BIOLOGICAL: Autologous Mesothelin-specific TCR-T Cells|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficiency of Word Prediction Software to Text Input Speed for Tetraplegia
Status: COMPLETED
Conditions: Settings Word Prediction Software|Rehabilitation Program
Interventions: OTHER: Rehabilitation program|OTHER: Self - Training at home
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Aromatherapy for Facial Aesthetics in Alleviating Signs of Aging: Pilot Study
Status: NOT_YET_RECRUITING
Conditions: Aging Well
Interventions: COMBINATION_PRODUCT: Geranium (Pelargonium graveolens) essential oil (EO) diluted to 1% in All.me Beauty® Gel Sérum Biocompatível|OTHER: Gel Sérum Biocompatível All.me Beauty®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Evaluate ZADAXIN's® (Thymalfasin) Ability to Enhance Immune Response to the H1N1sw Influenza Vaccine
Status: COMPLETED
Conditions: END STAGE RENAL DISEASE
Interventions: BIOLOGICAL: MF59 adjuvanted H1N1 influenza monovalent vaccine|DRUG: Thymosin alpha 1|DRUG: Thymosin alpha 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant HAIC of TACE Plus Donafenib in BCLC B Stage HCC: a Multi-center Randomized Controlled Trial.
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: HAIC|PROCEDURE: TACE|DRUG: FOLFOX|DRUG: cTACE or DEB-TACE|DRUG: Donafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Dexamethasone vs Dexamethasone Plus Magnesium Sulphate for Pain Relief in Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: dexamethasone|DRUG: magnesium sulphate|DRUG: Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Potential DDIs When the Daclatasvir/Asunaprevir/BMS-791325 Three Drug Antiviral Combination Tablet (FDC) is Coadministered With a Cocktail of Cytochrome P450 (CYP) Probe Substrates and Transporter Probe Substrates (Digoxin and Pravastatin) in Healthy Subjects
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Cocktail|DRUG: DCV 3DAA FDC|DRUG: BMS-791325
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy of Adding Lower Extremity Weights on Balance in Children With Ataxic Cerebral Palsy
Status: UNKNOWN
Conditions: Ataxic Cerebral Palsy
Interventions: OTHER: adding lower extremity weights|OTHER: traditional physical therapy group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality, Ice Application and Self-injection and Self-test Fair, Pain and State Anxiety
Status: COMPLETED
Conditions: Injection Site Irritation|Fear of Pain
Interventions: DEVICE: motivational video production through virtual reality glasses|OTHER: Ice Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Bivalirudin|DRUG: Unfractionated heparin|DEVICE: Bare metal stent|DEVICE: Paclitaxel-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Effects of Sprinkled Format REDUCOSE in a Carbohydrate-rich, Mixed Meal on Post-prandial Glycemia
Status: COMPLETED
Conditions: Dietary Supplement
Interventions: DIETARY_SUPPLEMENT: Dietary Supplement: Sprinkled Format REDUCOSE.|OTHER: Reference control|OTHER: Active comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety and Drug Detection Study of Dapivirine Vaginal Ring and Oral TRUVADA® in Breastfeeding Mother-Infant Pairs
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Dapivirine (DPV) Vaginal Ring (VR)-004|DRUG: Truvada Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Two Analgesic Methods for Pain Relief Following Surgical Abortion
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: Paracetamol|DRUG: lornoxicam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Local Only Anesthesia Versus Sedation in Patients Undergoing Bilateral Carpal Tunnel Release
Status: COMPLETED
Conditions: Bilateral Carpal Tunnel Syndrome (Diagnosis)
Interventions: PROCEDURE: Local only anesthesia vs Local with sedation anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First in Human Study in Healthy Volunteers Followed With Dosing in Participants With Lung or Liver Fibrosis
Status: COMPLETED
Conditions: Fibrosis
Interventions: DRUG: BLD-2660
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optilume BPH Catheter System in Benign Prostatic Hyperplasia (BPH)
Status: NOT_YET_RECRUITING
Conditions: Benign Prostatic Hyperplasia
Interventions: DEVICE: Optilume Catheter System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radical Prostatectomy and Perioperative Fluid Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Standard therapy|PROCEDURE: Maximization of cardiac stroke volume with fluid infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Rebif® Compared With Avonex® in the Treatment of Relapsing-remitting Multiple Sclerosis (MS)
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Rebif®|DRUG: Avonex®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Clinical Effect of TCM Sniffing Therapy Combined With Electroacupuncture in PSCI
Status: RECRUITING
Conditions: Stroke
Interventions: DIETARY_SUPPLEMENT: control|OTHER: Electronuchal acupuncture group treatment|OTHER: Smell therapy group treatment|OTHER: Electronuchal acupuncture combined with smell and inhalation therapy group treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Arbaclofen Placarbil in Subjects With Spasticity Due to Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Arbaclofen placarbil 15 mg BID|DRUG: Placebo|DRUG: Arbaclofen placarbil 30 mg BID|DRUG: Arbaclofen placarbil 45 mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human Granulocyte Monocyte - Colony Stimulating Factor (GM CSF) for Prevention of Pneumonia in Patients With Cirrhosis
Status: UNKNOWN
Conditions: Cirrhosis
Interventions: DRUG: GMCSF|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Focussed Echocardiography to Detect Preoperative Hypovolemia and Left Ventricular Dysfunction as a Predictor of Post-Induction Hypotension
Status: UNKNOWN
Conditions: Hypotension
Interventions: OTHER: Pre operative Focus assessed Transthoracic echocardiographic assessment.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact of Intraoperative Systemic Lidocaine Infusion on Chronic Postoperative Pain After Video-assisted Thoracic Surgery (VATS)
Status: COMPLETED
Conditions: Lung Cancer(Primary, Metastatic)|Benign Lung Mass Requiring Operation
Interventions: DRUG: Systemic intravenous lidocaine infusion|DRUG: Normal saline infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bacterial Load Reduction by GentleWave and EdgePro Irrigation Systems in Mandibular Necrotic Molars
Status: NOT_YET_RECRUITING
Conditions: Pulp Necroses
Interventions: DEVICE: GentleWave|DEVICE: EdgePro laser irrigation|DEVICE: Irrisafe passive ultrasonic irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label, Phase I/IIa Study of VAC-3S in HIV-1 Patients Who Showed an Immune Response to VAC-3S During IVVAC-3S/P1
Status: UNKNOWN
Conditions: HIV
Interventions: BIOLOGICAL: VAC-3S
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual Versus Triple Protease Inhibitor Combinations, Including Ritonavir, in HIV Infected People
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Fosamprenavir|DRUG: Lopinavir/Ritonavir|DRUG: Ritonavir|DRUG: Tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastric Content After 6 vs 4 Hours of Preoperative Fasting in Children
Status: RECRUITING
Conditions: Pulmonary Aspiration of Gastric Contents
Interventions: PROCEDURE: Preoperative fasting instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of TQB2303 in Patients With Aggressive CD20 Positive Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Non-hodgkin's Lymphoma
Interventions: DRUG: TQB2303|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lurbinectedin With or Without Avelumab in Small Cell Carcinoma of the Bladder (LASER)
Status: RECRUITING
Conditions: Small Cell Carcinoma of the Bladder|High Grade Neuroendocrine Tumors of the Urinary Tract
Interventions: DRUG: Lurbinectedin|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Efficacy and Safety of Cobimetinib Plus Atezolizumab in Participants With Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Cobimetinib|DRUG: Atezolizumab|DRUG: Atezolizumab Cohort 7
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib, Pomalidomide, Dexamethasone For Systemic AL Amyloidosis
Status: RECRUITING
Conditions: Systemic Amyloidosis
Interventions: DRUG: Bortezomib|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of INTRA Spine Non Fusion Technique in the Treatment of Lumbar Degenerative Disease
Status: ENROLLING_BY_INVITATION
Conditions: Lumbar Degenerative Disease
Interventions: OTHER: Non-fusion group|OTHER: Fusion group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Substitution of 5-FU (Fluorouracil) by Capecitabine in Scheme of Chemo-radiotherapy in Patients With Squamous Cell Carcinoma of the Anal Canal.
Status: COMPLETED
Conditions: Anal Canal Cancer.
Interventions: DRUG: Capecitabine|DRUG: Mitomycins|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Glofitamab Plus Polatuzumab-R-CHP for Patients With High-risk Diffuse Large B-cell Lymphoma
Status: RECRUITING
Conditions: Lymphoma|Lymphoma, Large B-Cell, Diffuse
Interventions: DRUG: Glofitamab|DRUG: Polatuzumab|DRUG: Rituximab|DRUG: Doxorubicin Hydrochloride|DRUG: Cyclophosphamide|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chlorhexidine Gluconate Solution at 0.125% vs Placebo for the Healing of Grade IIB Ulcers of Diabetic Foot
Status: UNKNOWN
Conditions: Diabetic Foot
Interventions: DRUG: Chlorhexidine gluconate at 0.125%|DRUG: Placebo Comparator with physiological saline sterile solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dynamic Individualized rTMS Based on fNIRS
Status: UNKNOWN
Conditions: Stroke|Rehabilitation|Repetitive Transcranial Magnetic Stimulation|Functional Near-infrared Spectroscopy
Interventions: OTHER: Individualized rTMS strategy|OTHER: Traditional rTMS strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nicotinamide Treatment for Lupus-associated Skin Lesions in Lupus Erythematosus
Status: UNKNOWN
Conditions: Cutaneous Lupus Erythematosus|Systemic Lupus Erythematosus Rash
Interventions: DRUG: nicotinamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stabilizing Training in Degenerative Disc Disease
Status: COMPLETED
Conditions: Degenerative Disc Disease|Protrusion|Extrusion of Migrated Disc|Hernia
Interventions: BEHAVIORAL: Stabilizing training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Remodeling Around Implants With Two Different Surfaces Placed in Horizontally Augmented Bone
Status: UNKNOWN
Conditions: Dental Implantation|Bone Remodeling
Interventions: DEVICE: Implant insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Clinical Efficacy of Intravenous Application of Hemostatic Drugs in Improving the Clarity of Vision Under Endoscope, Perioperative Bleeding Volume and Anti-inflammatory Effect of Spinal Endoscopic Lumbar Fusion
Status: NOT_YET_RECRUITING
Conditions: Lumbar Spondylolisthesis|Arthrosis; Spine
Interventions: DRUG: Caroxime sodium sulfonate|DRUG: Desmopressin|DRUG: 0.9% Sodium Chloride Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Serratus Plane Block After Minimally Invasive Mitral Valve Repair
Status: RECRUITING
Conditions: Minimal Invasive Cardiac Surgery|Minimal Invasive Cardiac Surgery Mitral Valve Surgery|Serratus Anterior Plane Block
Interventions: DRUG: Continous SAPB (Ropivacain)|OTHER: institutional standard of care pain medication protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ultrasound Guidance Versus Electrical Stimulation for Perineural Catheter Insertion
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: perineural mepivicaine catheter placed via ultrasound or electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Irofulven in Patients With Hormone-refractory Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Irofulven|DRUG: Prednisone|DRUG: Mitoxantrone|DRUG: Capecitabine|DRUG: Irofulven
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Baseball Suturing on Isthmocele and Residual Myometrial Thickness After Cesarean
Status: COMPLETED
Conditions: Isthmocele|Cesarean Section Complications
Interventions: PROCEDURE: Uterine closure with "Baseball" suture technique|PROCEDURE: Single Layer Continuous Locked
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Whole Grain on Gut Microbiome and Metabolic Health
Status: UNKNOWN
Conditions: Metabolic Disease|Injury of Gastrointestinal Tract
Interventions: OTHER: Whole grain|OTHER: Refined grain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Irbesartan and Amlodipine Combination in Controlling Blood Pressure
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: IRBESARTAN (SR47436)|DRUG: Amlodipine|DRUG: Irbesartan / Amlodipine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT