pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Resuscitation With Plasma in Surgical and Trauma Patients With Septic Shock
Status: TERMINATED
Conditions: Septic Shock
Interventions: DRUG: Plasma|DRUG: Balanced crystalloids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Online Training Tools in Pediatric Resuscitation
Status: ACTIVE_NOT_RECRUITING
Conditions: Family-centered Care in Pediatric Resuscitation
Interventions: OTHER: FACETS: Pediatric Resuscitation|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: XIENCE V® Everolimus Eluting Coronary Stent System USA Post-Approval Study (XIENCE V® USA-Phase 1)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: XIENCE V® Everolimus Eluting Coronary Stent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CEUS Targeted Biopsies Compared to mpMRI Targeted and Systematic Biopsies for the Detection of Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer|Prostatic Neoplasms
Interventions: OTHER: CEUS and targeted biopsies|OTHER: MRI and targeted biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Family Access to Dentist Study
Status: COMPLETED
Conditions: Dental Caries
Interventions: BEHAVIORAL: Standard letter|BEHAVIORAL: Intervention letter|BEHAVIORAL: Reduced intervention letter|BEHAVIORAL: DIG|BEHAVIORAL: Reduced DIG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Application of Celiac Plexus Block in Postoperative Analgesia of Upper Abdominal Surgery
Status: COMPLETED
Conditions: Pain, Postoperative|Nerve Block
Interventions: PROCEDURE: Celiac plexus block|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RBG: Regular, Bare, Gel: Does Type of Nail Polish Affect Bacterial Counts After Surgical Scrubbing?
Status: COMPLETED
Conditions: Bacterial Infections|Surgical Site Infection|Contaminated Medical or Biological Substances
Interventions: OTHER: Nail polish application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Two Non-diffractive Enhanced Monofocal Intraocular Lenses
Status: RECRUITING
Conditions: Cataract
Interventions: DEVICE: Evolux|DEVICE: Tecnis Eyhance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized, Controlled Study of IFX-1 in Patients With Severe COVID-19 Pneumonia
Status: COMPLETED
Conditions: Severe COVID-19 Pneumonia
Interventions: DRUG: IFX-1 + BSC|DRUG: BSC|DRUG: IFX-1 + SOC|DRUG: Placebo + SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of VB-201 in Patients With Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: VB-201 80mg|DRUG: VB-201 160mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventive Osteopathic Treatment of Plagiocephaly
Status: COMPLETED
Conditions: Positilonal Deformation of the Skull|Head Turn Preference|Axial Hypertony
Interventions: PROCEDURE: manual therapy/osteopathy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Spinal Mobilizations on Neck Pain and Sympathetic Nervous System Activity in People With Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Neck passive mobilizations|OTHER: Manual contact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Activation, Counseling and Exercise - Acute Leukemia (PACE-AL)
Status: COMPLETED
Conditions: Acute Leukemia
Interventions: OTHER: Exercise based multimodal intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Efficacy and Safety of Entelon Tab. 150mg in Patients With Osteoarthritis of Knee
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Enteron tab. 150mg(vitis vinifera extract 150mg) : twice daily for 12 weeks|DRUG: Celebrex cap. (celecoxib 200mg) : once daily, for 12 weeks|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Manipulation or Microdiscectomy For Sciatica? A Prospective Randomized Controlled Trial.
Status: COMPLETED
Conditions: Sciatica|Intervertebral Disk Displacement
Interventions: PROCEDURE: Spinal Manipulation, Microdiscectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Chemomechanical Caries Removal Using Papain Gel
Status: COMPLETED
Conditions: Dental Caries
Interventions: PROCEDURE: Chemomechanical Caries Removal|PROCEDURE: Conventional method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: External Negative Pressure Dressing System vs. Traditional Wound Dressing for Cesarean Section Incision in Obese Women.
Status: COMPLETED
Conditions: Wound Dehiscence
Interventions: DEVICE: External negative pressure dressing system (Yuwell 7E-A portable suction unit)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Management of Intraoperative Fluids in Ambulatory Surgery
Status: UNKNOWN
Conditions: Anesthesia, General|Fluid Therapy|Ambulatory Surgical Procedures
Interventions: OTHER: Fluid therapy protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dendritic Cell (DC) Vaccine for Malignant Glioma and Glioblastoma
Status: COMPLETED
Conditions: Malignant Glioma|Glioblastoma Multiforme|Anaplastic Astrocytoma|High Grade Glioma
Interventions: BIOLOGICAL: Dendritic Cell Vaccine|BIOLOGICAL: Tumor Lysate|DRUG: Imiquimod|PROCEDURE: Leukapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visceral Manipulation in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: OTHER: Active Visceral Manipulation|OTHER: Standard care physiotherapy|OTHER: Placebo Visceral Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Polyphenol-containing Beverages on the Immune System and on Muscular Growth Factors
Status: COMPLETED
Conditions: Food Sensitivity
Interventions: OTHER: non-alcoholic Pilsner|OTHER: non-alcoholic wheat beer|OTHER: apple spritzer|OTHER: lemonade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Treatment of Suspected Cholelithiasis With Nitroglycerin
Status: UNKNOWN
Conditions: COLIC|BILIARY TRACT DISEASES
Interventions: DRUG: sublingual nitroglycerine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Portable Scalp Cooling System for the Improvement of Chemotherapy-Induced Hair Loss in Patients With Metastatic Breast Cancer
Status: WITHDRAWN
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Metastatic Breast Carcinoma
Interventions: DEVICE: Cold Cap Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oral Absorbent and Probiotics in CKD Patients With PAD on Gut Microbiota, IncRNA, Metabolome, and Vascular Function
Status: RECRUITING
Conditions: CKD|PAD - Peripheral Arterial Disease
Interventions: DIETARY_SUPPLEMENT: Active bamboo charcoal|DIETARY_SUPPLEMENT: probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bioequivalence of An Oral Mercaptopurine Suspension 100 Mg / 5 Ml Versus Tablet in Healthy Male Subjects Under Fasting Conditions
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Mercaptopurine 20mg/ml oral suspension|DRUG: Mercaptopurine 50mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and/or Hormone Therapy With or Without Zoledronate in Treating Women With Stage II or Stage III Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Metastatic Cancer
Interventions: DRUG: zoledronic acid|PROCEDURE: adjuvant therapy|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eating, Sleeping, Consoling for Neonatal Withdrawal (ESC-NOW): a Function-Based Assessment and Management Approach
Status: ACTIVE_NOT_RECRUITING
Conditions: Neonatal Opiate Withdrawal Syndrome
Interventions: OTHER: Finnegan Neonatal Abstinence Scoring Tool|OTHER: Eat, Sleep, Console (ESC) care tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Research of Laser Ablation for the Treatment of Lower Anogenital Tracts' Precancerous Lesions
Status: RECRUITING
Conditions: Squamous Intraepithelial Lesions|Laser Burn
Interventions: PROCEDURE: laser ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diazepam Buccal Film (DBF) - Diastat Rectal Gel (DRG) Crossover Study
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Diazepam Buccal Film|DRUG: Diastat® Rectal Gel (Valeant Pharmaceuticals USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2a Study of IMM-1-104 in Participants With Previously Treated, RAS-Mutant, Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|Pancreatic Adenocarcinoma|Malignant Melanoma (Cutaneous)|Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: IMM-1-104 Monotherapy (Treatment Group A)|DRUG: IMM-1-104 + modified Gemcitabine/nab-Paclitaxel (Treatment Group B)|DRUG: IMM-1-104 + modified FOLFIRINOX (Treatment Group C)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating Efficacy and Safety of Biphasic Insulin Aspart 50 Twice Daily Versus Biphasic Human Insulin 50 Twice Daily Both in Combination With Metformin in Chinese Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 50|DRUG: biphasic human insulin 50
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The PACT (Patient Activation Through Conversations) Study
Status: RECRUITING
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Patient Activation through Conversations (PACT) Program|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Antibody Persistence, Boostability & Safety in Previously Primed Subjects.
Status: COMPLETED
Conditions: Haemophilus Influenzae Type b|Tetanus|Whole Cell Pertussis|Hepatitis B|Diphtheria
Interventions: BIOLOGICAL: DTPw-HBV/Hib-MenAC conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial Involving Treatment of BB2603 in Subjects With Distal Subungual Onychomycosis of the Toenail
Status: COMPLETED
Conditions: Distal Subungual Onychomycosis|Fungal Infection|Fungus, Nail
Interventions: DRUG: BB2603-1|DRUG: BB2603-3|DRUG: BB2603-10|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Phase II Study of the Combination of GSK2118436 and GSK1120212 in Patients With Metastatic Melanoma Which is Refractory or Resistant to BRAF Inhibitor
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: GSK2118436|DRUG: GSK1120212
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of 2-octylcyanoacrylate With Full-thickness Skin Grafts
Status: COMPLETED
Conditions: Wound Closure Techniques
Interventions: PROCEDURE: Wound Closure with 2-octylcyanoacrylate|PROCEDURE: Wound Closure with 5-0 Vicryl Sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oral Contraceptive Pill Compared With Vitamin E in Women With Migraine
Status: RECRUITING
Conditions: Migraine|Migraine;Menstrual
Interventions: DRUG: Ethinylestradiol/levonorgestrel|DRUG: Vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Feasibility Study Evaluating the Performance of Focused Multipolar Stimulation in Adult Cochlear Implant Recipients
Status: RECRUITING
Conditions: Hearing Impairment
Interventions: DEVICE: Focused stimulation strategy|DEVICE: ACE stimulation strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Different Formulations of Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: Bimatoprost 0.03% Formulation B Ophthalmic Solution|DRUG: Bimatoprost 0.03% Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bacterial Vaginosis; A Randomized Trial to Reduce Recurrence
Status: COMPLETED
Conditions: Bacterial Vaginosis
Interventions: OTHER: hygienic information plus 62% ethyl alcohol in emollient gel|OTHER: hygienic information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Cryopreserved Amniotic Membranes in the Care of Resistant Vascular Ulcers
Status: TERMINATED
Conditions: Resistant Vascular Ulcers
Interventions: PROCEDURE: amniotic membranes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of Sustainable Eating Pattern to Limit Malnutrition in Older Adults
Status: NOT_YET_RECRUITING
Conditions: Malnutrition|Sarcopenia
Interventions: OTHER: Nutrition intervention (dietary protocol)|OTHER: Hospital standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavior of Valve Leaflets Following Aortic Valve Implant
Status: COMPLETED
Conditions: Aortic-valve Replacement
Interventions: DIAGNOSTIC_TEST: 4D Cardiac CT Scan|DEVICE: LivaNova Bioprothetic Aortic Valve Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of Endovascular Cooling Device in Patients With Hypothermic Cardiopulmonary Resuscitation
Status: UNKNOWN
Conditions: Cardiac Arrest
Interventions: DEVICE: ICY catheter, Thermoguard device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Low Flow Anesthesia on Postoperative Emergence Agitation in Rhinoplasty
Status: COMPLETED
Conditions: Emergence Agitation|Anesthetics|Rhinoplasty
Interventions: OTHER: : Conventional flow Anesthesia|OTHER: Low Flow Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Dural Puncture Epidural Versus Epidural Anesthesia for Cesarean Delivery
Status: COMPLETED
Conditions: Pain Levels
Interventions: DEVICE: 25G Dural Puncture Epidural|DEVICE: Standard Epidural
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open Label, Phase II Trial of Continuous Low-Irradiance Photodynamic Therapy (CLIPT) Using Verteporfin (Visudyne®) for the Treatment of Cutaneous Metastases of Breast Cancer
Status: UNKNOWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Verteporfin|DEVICE: Continuous Low-Irradiance Photodynamic Therapy (CLIPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Soy Protein on Post- Breast Cancer Surgery Pain
Status: TERMINATED
Conditions: Pain|Chronic Disease|Breast Cancer
Interventions: DIETARY_SUPPLEMENT: Isolated soy protein|DIETARY_SUPPLEMENT: Isolated milk protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Antineoplaston Therapy in Treating Adults With Residual/Recurrent/Progressive Glioblastoma Multiforme
Status: COMPLETED
Conditions: Glioblastoma Multiforme of the Brain
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of NGM831 as Monotherapy and in Combination With Pembrolizumab or Pembrolizumab and NGM438 in Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Pancreatic Cancer|Breast Cancer|Gastric Cancer|Non-small Cell Lung Cancer|Cervical Cancer|Endocervical Cancer|Squamous Cell Carcinoma of Head and Neck|Bladder Urothelial Cancer|Colorectal Carcinoma|Esophageal Cancer|Ovarian Cancer|Renal Cell Carcinoma|Prostate Cancer|Melanoma|Mesothelioma|Cholangiocarcinoma
Interventions: DRUG: NGM831|DRUG: NGM831 plus pembrolizumab (KEYTRUDA®)|DRUG: NGM831 and NGM438 plus pembrolizumab (KEYTRUDA®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Discontinuing Contact Precautions for Extended-spectrum β-lactamase Enterobacteriaceae in a Geriatric Unit
Status: RECRUITING
Conditions: Infection, Hospital
Interventions: OTHER: Discontinuation of contact precautions for ESBLE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Oral Administration of Methylene Blue MMX Tablets on Double Stranded DNA
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: PROCEDURE: standard white light colonoscopy-equivalent to placebo|DRUG: Methylene Blue MMX tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Safety and Efficacy of AZD4547 Combination With Tislelizumab in Patients With mUC
Status: RECRUITING
Conditions: Urothelial Carcinoma
Interventions: DRUG: AZD4547|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of the Safety and Efficacy of UK-500,001 in Adult Patients With COPD
Status: TERMINATED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: UK-500,001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Metformin Hydrochloride Extended-Release Tablets USP 750 mg Under Fed Condition
Status: COMPLETED
Conditions: Fasting
Interventions: DRUG: Metformin Hydrochloride Extended-Release Tablets USP 750|DRUG: GLUCOPHAGE®XR tablet 750 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telepharmacy on Patients With Arterial Hypertension
Status: RECRUITING
Conditions: Hypertension
Interventions: OTHER: Pharmaceutical care via telepharmacy and usual care|OTHER: Pharmaceutical care in-person and usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Omadacycline Tissue Penetration in Diabetic Patients With Wound Infections and Healthy Volunteers Via In Vivo Microdialysis
Status: COMPLETED
Conditions: Diabetes|Wound Infection|Healthy Volunteers
Interventions: DRUG: Omadacycline|PROCEDURE: Microdialysis Catheter Insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Letrozole add-on in the Treatment of Cesarean Scar Pregnancy
Status: COMPLETED
Conditions: Cesarean Scar Pregnancy
Interventions: DRUG: MTX monotherapy|DRUG: MTX + letrozole add-on
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STATE Trial: SusTained Attention Training to Enhance Sleep
Status: COMPLETED
Conditions: Insomnia
Interventions: OTHER: Computerized Plasticity-Based Adaptive Cognitive Training|OTHER: Commercially available computerized training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The GENPET Study - An Imaging Study of FCH-PET-CT in Men With Prostate Cancer and a DNA Repair Gene Mutation.
Status: RECRUITING
Conditions: Prostate Cancer|BRCA Mutation|Mismatch Repair Gene Mutation|ATM Gene Mutation|HOXB13 Germline Mutation|CHEK2 Gene Mutation|PALB2 Gene Mutation
Interventions: OTHER: MRI pelvis or CT imaging under clinical management for Pr Ca|OTHER: Whole body bone scan imaging|OTHER: PET-CT imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Postoperative Pain Management in Patients Undergoing Laparoscopic Colorectal Surgery Under Enhanced Recovery After Surgery (ERAS) Program, Laparoscopic Colorectal Surgery Without ERAS and Open Colorectal Surgery
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: Celecoxib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Azithromycin in Treatment of Bronchiectasis
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: DRUG: Azithromycin|DRUG: Placebo for Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-CAR T Cell Therapy for Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: Muc1/CLL1/CD33/CD38/CD56/CD123-specific gene-engineered T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Of New Onset Postoperative Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation New Onset
Interventions: DEVICE: CorMatrix ECM for Pericardial Closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Pharmacokinetics of an Oral Contraceptive When Co-administered With GSK2248761 in Healthy Adult Female Subjects.
Status: TERMINATED
Conditions: Infection, Human Immunodeficiency Virus|HIV Infections
Interventions: DRUG: YASMIN|DRUG: GSK2248761|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: tislelizUMaB in canceR Patients With molEcuLar residuaL Disease
Status: NOT_YET_RECRUITING
Conditions: Cancer|Lung Cancer|Colo-rectal Cancer|Pancreas Cancer|Soft Tissue Sarcoma
Interventions: DRUG: Tislelizumab|OTHER: Blood sampling|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S0348 Vaccine Therapy in Treating Patients With Stage IIIB or Stage IV Breast Cancer in Remission
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: recombinant modified vaccinia Ankara-5T4 vaccine|PROCEDURE: adjuvant therapy|PROCEDURE: recombinant viral vaccine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIPEC as Neoadjuvant Treatment for Resectable Pancreatic Adenocarcinoma
Status: WITHDRAWN
Conditions: Pancreatic Neoplasms|Pancreatic Adenocarcinoma
Interventions: PROCEDURE: Hyperthermic intraperitoneal chemotherapy|PROCEDURE: Open pancreaticoduodenectomy|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TA-8995 With Single, Escalating Doses in Healthy Subjects
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: TA-8995|DRUG: TA-8995|DRUG: TA-8995|DRUG: TA-8995|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Daclatasvir and Asunaprevir With Chronic HCV Genotype 1b Infection and Chronic Renal Failure
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Daclatasvir plus Asunaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of OPB-31121 in Patients With Progressive Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: OPB-31121|DRUG: OPB-31121 phase2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter, Open-label, Clinical and Pharmacokinetic Study of PM060184 in Combination With Gemcitabine in Selected Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Gemcitabine plus PM060184
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Relationship Between Treatment With Bach´s Flower Remedy and Spiritual Well-Being of People With Common Mental Disorder
Status: COMPLETED
Conditions: Mental Disorders|Personal Well Being
Interventions: OTHER: Bach´s Flower Remedy|OTHER: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study: Lipoic Acid and Omega-3 Fatty Acids for Alzheimer's Prevention
Status: COMPLETED
Conditions: Treated Hypertension
Interventions: DRUG: Lipoic Acid plus Omega-3 Fatty Acids|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The WORLD (Weight Optimization: Revamping Lifestyles Using the Dietary Guidelines) Study - Developing, Implementing, and Testing an Education Program
Status: COMPLETED
Conditions: Obesity|Cardiovascular Disease
Interventions: BEHAVIORAL: Moderate-fat|BEHAVIORAL: Lower-fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Difference in the Mechanism of Action Between Two Brands of Dexamfetamine in Adults With ADHD
Status: RECRUITING
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Dexamfetamine|DRUG: Dexamfetamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Suprazygomatic Block in Cleft Palate Surgery in Children
Status: COMPLETED
Conditions: Cleft Palate
Interventions: DRUG: Bupivacaine|DRUG: Dexmedetomidine|DRUG: paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Temsirolimus + Sorafenib in Advanced Hepatocellular Carcinoma (HCC)
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Temsirolimus + Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Implementation of a Food and Nutritional Support Strategy Adapted to Dependent Elderly Subjects
Status: COMPLETED
Conditions: Nutrition|Elderly
Interventions: DIETARY_SUPPLEMENT: population living at home with meals on wheels|DIETARY_SUPPLEMENT: population living in an EHPAD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Relative Bioavailability of Pimasertib in Cancer Patients
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Pimasertib Capsule (Part A)|DRUG: Pimasertib Tablet (Part A)|DRUG: Pimasertib Tablet (Part A)|DRUG: Pimasertib Capsule (Part A)|DRUG: Pimasertib Capsule (Part B and trial extension phase)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Etanercept and Methotrexate in Patients to Induce Remission in Early Arthritis (EMPIRE)
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Inflammatory Arthritis
Interventions: DRUG: Etanercept (ETN)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Baduanjin Sequential Therapy and Cardiac Function of AMI With Reduced EF After PCI
Status: UNKNOWN
Conditions: AMI
Interventions: BEHAVIORAL: Baduanjin sequential therapy|BEHAVIORAL: Aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SweetMama: Testing of a Novel Technology for Diabetes Education and Support to Pregnant Women
Status: COMPLETED
Conditions: Diabetes Mellitus in Pregnancy
Interventions: BEHAVIORAL: SweetMama Focus Groups|BEHAVIORAL: SweetMama Individual Testing|BEHAVIORAL: SweetMama Feasibility Testing - Pilot Randomized Trial
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Joint Loading vs Normal Physiotherapy Care in Degenerative Knees (V1)
Status: UNKNOWN
Conditions: Osteo Arthritis Knee
Interventions: PROCEDURE: Knee Loading protocol|PROCEDURE: Routine Physiotherapy Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of MyStar DoseCoach to Routine Titration in Adult Patients With Type 2 Diabetes Mellitus Using Toujeo
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin glargine (U300)|DEVICE: MyStar DoseCoach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CIPHER Study: Pilot Study to Study the Role of ctDNA in Triple Negative and HER2 Positive Early Stage
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer, Early-Onset
Interventions: DRUG: Neoadjuvant chemotherapy administered before surgical extraction of a tumor|OTHER: Observational
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of LY3502970 in Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY3502970|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Concave Supra-arch Branched Stent-Graft System for Endovascular Treatment of Aortic Arch Diseases
Status: NOT_YET_RECRUITING
Conditions: Aortic Arch Aneurysm|Penetrating Aortic Ulcer
Interventions: DEVICE: Concave Supra-arch Branched Stent-Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Omalizumab (Xolair) in Subjects With Moderate to Severe Persistent Asthma (EXTRA)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: omalizumab (Xolair)|DRUG: placebo|DRUG: corticosteroids|DRUG: long-acting beta-agonists
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Walking Ability in Patients With Peripheral Artery Occlusive Disease
Status: TERMINATED
Conditions: Peripheral Arterial Disease
Interventions: DRUG: Placebo|DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HFNC Flow Titration and Effort of Breathing in the PICU
Status: COMPLETED
Conditions: High Flow Nasal Cannula
Interventions: DEVICE: Fisher & Paykel high flow nasal cannula|DEVICE: Vapotherm high flow nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Consequences of Anti-interleukin 6 Immunotherapy Treatment for Rheumatoid Arthritis on Periodontium
Status: TERMINATED
Conditions: Rheumatoid Arthritis|Periodontitis
Interventions: OTHER: oral exam and
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Immunotherapy With BHT-3009 Alone or Combined With Atorvastatin in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: BHT-3009-01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Omega 3 Fats on Sperm Quality and Sexual Function
Status: TERMINATED
Conditions: Infertility
Interventions: DRUG: omega 3 fats|DRUG: folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gluten-free Diet in Women With Autoimmune Thyroiditis
Status: COMPLETED
Conditions: Autoimmune Thyroiditis
Interventions: OTHER: Gluten-free diet|OTHER: Gluten capsules supplementation|OTHER: Placebo capsules supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Efficacy and Safety of RPH-104 in Adult Subjects With Schnitzler Syndrome
Status: NOT_YET_RECRUITING
Conditions: Schnitzler Syndrome|Urticarial Vasculitis With Monoclonal Immunoglobulin M Component, Schnitzler (Disorder)
Interventions: BIOLOGICAL: 80 mg RPH-104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Deep Brain Stimulation in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: 1 : S-C1-C2|DEVICE: 2 : S-C2-C1|DEVICE: 3 : C1 - S - C2|DEVICE: 4 : C1 -C2 - S|DEVICE: 5 : C2 - S - C1|DEVICE: 6 : C2 - C1 - S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Oral Contraceptives for Treating Premenstrual Dysphoric Disorder in Bipolar Disorder
Status: RECRUITING
Conditions: Premenstrual Dysphoric Disorder|Bipolar Disorder
Interventions: DRUG: Yaz|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Palliative Care in Patients With Metastatic Upper Gastrointestinal Cancers Treated With First-line Chemotherapy
Status: COMPLETED
Conditions: Gastric Cancer|Pancreas Cancer|Bile Duct Cancer|Gastroesophageal Cancer|Esophageal Cancer
Interventions: BEHAVIORAL: Early Palliative Care visit|OTHER: EORTC-QLQ-C30 questionnaire|OTHER: HADS score
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Korean Red Ginseng and Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Korean red ginseng|DIETARY_SUPPLEMENT: starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transdermal Absorption of Dimercaptopropane-1-Sulfonate (DMPS) and Effect on Urinary Mercury Excretion
Status: COMPLETED
Conditions: Toxicity
Interventions: DRUG: transdermal DMPS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Respiratory Muscle Training in Individuals With Long-term Post-COVID-19 Symptoms
Status: COMPLETED
Conditions: Covid19|Post-acute COVID-19 Syndrome
Interventions: OTHER: Inspiratory + expiratory muscle training group|OTHER: Inspiratory + expiratory muscle training sham group|OTHER: Exercise training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Flexible Band vs Rigid Ring for Degenerative Mitral Valve Disease
Status: COMPLETED
Conditions: Mitral Regurgitation
Interventions: PROCEDURE: Mitral valve repair|DEVICE: Ring annuloplasty with posterior band|DEVICE: Ring annuloplasty with complete ring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Debritom - Micro Water Jet Technology and Wound Healing
Status: TERMINATED
Conditions: Diabetic Foot Ulcer|Non-healing Wound|Non-Healing Ulcer of Skin|Venous Leg Ulcer|Venous Ulcer
Interventions: DEVICE: Debritom
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Randomized Study of Cyclophosphamide With or Without Antithymocyte Globulin Before Bone Marrow Transplantation in Patients With Aplastic Anemia
Status: COMPLETED
Conditions: Aplastic Anemia
Interventions: DRUG: Anti-thymocyte globulin|DRUG: Cyclophosphamide|PROCEDURE: Bone marrow transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Saroglitazar Magnesium in the Treatment of Non-Alcoholic Steatohepatitis
Status: COMPLETED
Conditions: Non Alcoholic Steatohepatitis
Interventions: DRUG: Saroglitazar Magnesium 2mg|DRUG: Saroglitazar Magnesium 4mg|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Fluvastatin 40 mg (b.i.d.) in the Prevention of the Development of Vasculopathy of the Graft in de Novo Renal Transplant Patients Transplant
Status: COMPLETED
Conditions: Graft Vasculopathy
Interventions: DRUG: Fluvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of NeoThermo-Radio-chemotherapy for LA Rectal Cancer Before Laparoscopic TME: Prospective Phase II Trial
Status: TERMINATED
Conditions: Locally Advanced Rectal Cancer
Interventions: RADIATION: Hyperthermia with concurrent chemo-radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Radiofrequency and Balloon Compression in the Treatment of Idiopathic Trigeminal Neuralgia
Status: TERMINATED
Conditions: Trigeminal Neuralgia
Interventions: PROCEDURE: Balloon Compression Rhizotomy|PROCEDURE: Radiofrequency Thermal Coagulation Rhizotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fear to Fall Reduction in Geriatric Patients Who Suffered Previous Falls
Status: UNKNOWN
Conditions: Geriatric Disorder
Interventions: OTHER: Physiotherapy intervention|BEHAVIORAL: Cognitive-behavioural Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Effect of Tegaserod (2 mg Tid and 6 mg Tid) on Dyspeptic Symptoms in Diabetic Patients With Symptoms of Diabetic Gastropathy
Status: TERMINATED
Conditions: Diabetic Gastropathy
Interventions: DRUG: Tegaserod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: WEGENT - Comparison of Methotrexate or Azathioprine as Maintenance Therapy for ANCA-Associated Vasculitides
Status: UNKNOWN
Conditions: Systemic Wegener's Granulomatosis
Interventions: DRUG: Azathioprine: 2 mg/kg/day|DRUG: methotrexate 0.3 mg/kg/week, to a maximum and optimal dose of 25 mg/week
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Letrozole or Combined Clomiphene Citrate Metformin as a First Line Treatment in Women With Polycystic Ovarian Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Letrozole|DRUG: Clomiphene|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Intraoperative Methadone Prevent Postoperative Pain in Bariatric Surgery?
Status: COMPLETED
Conditions: Pain, Postoperative|Chronic Pain
Interventions: DRUG: Use of Intraoperative Intravenous Methadone|DRUG: Use of Intraoperative Intravenous Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cryoablation Combined With Sintilimab Plus Lenvatinib in Patients With Immune Checkpoint Inhibitor Previously Treated Advanced Biliary Tract Cancer （CASTLE-08）
Status: RECRUITING
Conditions: Advanced Biliary Tract Cancer
Interventions: DRUG: Sintilimab|DRUG: Lenvatinib|PROCEDURE: Cryoablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EMAGINE 2.0 - Electromagnetic Field Ischemic Stroke - Novel Subacute Treatment
Status: NOT_YET_RECRUITING
Conditions: Ischemic Stroke
Interventions: DEVICE: BQ 3.0 system|DEVICE: BQ 3.0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does the Use of Intrathecal Morphine Increase the Length of Hospital Stay in Fast Track Orthopedic Procedures?
Status: COMPLETED
Conditions: Arthropathy of Knee|Arthropathy of Hip
Interventions: DRUG: Intrathecal Morphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PD 0332991 and Anastrozole for Stage 2 or 3 Estrogen Receptor Positive and HER2 Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Neoplasms
Interventions: DRUG: PD0332991|DRUG: Anastrozole|DRUG: Goserelin|PROCEDURE: Surgery (standard of care)|PROCEDURE: Tumor biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT