pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of PVE Applied in Addition to Pilates on Premenstrual Symptoms, Pain, Sleep and QoL in Individuals With PMS
Status: RECRUITING
Conditions: Premenstrual Syndrome|Pelvic Floor Disorders|Quality of Life
Interventions: OTHER: Pilates|OTHER: Pelvic floor exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Entecavir Plus Tenofovir in Patients With Chronic Hepatitis B Who Failed Previous Treatment
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Entecavir|DRUG: Tenofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Board Game Project for Adolescents With Tourette Syndrome
Status: UNKNOWN
Conditions: Tourette Syndrome in Adolescence|Depression|Mental Health Issue|Social Adjustment
Interventions: BEHAVIORAL: board game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nivolumab With or Without Stereotactic Radiosurgery in Treating Patients With Recurrent, Advanced, or Metastatic Chordoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Chordoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab|RADIATION: Stereotactic Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of Anti-retroviral Combinations for Treatment Naive, HIV Infected Persons in Resource-limited Settings
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Atazanavir|DRUG: Didanosine (enteric-coated)|DRUG: Efavirenz|DRUG: Emtricitabine|DRUG: Emtricitabine/Tenofovir disoproxil fumarate|DRUG: Lamivudine/Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Protein Supplementation After Bariatric Surgery
Status: COMPLETED
Conditions: Protein Malnutrition
Interventions: DRUG: Resource Instant Protein 88|DRUG: Resource Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial of Plate Fixation Versus Tension Band Wire for Olecranon Fractures
Status: COMPLETED
Conditions: Displaced Olecranon Fractures
Interventions: PROCEDURE: Tension Band Wiring|PROCEDURE: Plate fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Canadian Orthopaedic Foot and Ankle Society Surgical Treatment of Ankle Arthritis Outcome Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Ankle Arthritis
Interventions: PROCEDURE: Ankle Arthroplasty|PROCEDURE: Ankle Arthrodesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atomoxetine for Treatment of Weight Gain in Olanzapine or Clozapine Patients
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Diet support group|BEHAVIORAL: Group counseling and exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carbon Ions Radiation Therapy for Resectable or Borderline Resectable Pancreas Adenocarcinoma
Status: UNKNOWN
Conditions: Cancer of Pancreas|Pancreas Adenocarcinoma|Resectable Pancreatic Cancer
Interventions: DRUG: Preoperative chemotherapy|RADIATION: Preoperative radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Recombinant Herpes Zoster Vaccine (CHO Cells) in Healthy Subjects Aged 18 Years and Above
Status: ACTIVE_NOT_RECRUITING
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Low Dose Recombinant Herpes Zoster Vaccine (CHO cells)|BIOLOGICAL: High Dose Recombinant Herpes Zoster Vaccine (CHO cells)|BIOLOGICAL: Low dose adjuvant|BIOLOGICAL: High dose adjuvant|BIOLOGICAL: Positive control|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The British Heart Foundation SENIOR-RITA Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: NSTEMI - Non-ST Segment Elevation MI
Interventions: PROCEDURE: Coronary Angiography|PROCEDURE: Coronary revascularisation|OTHER: Optimal Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: L-DEP/DEP Regimen and PD-1 Antibody as a Treatment for Relapse/Refractory EBV-HLH
Status: NOT_YET_RECRUITING
Conditions: Hemophagocytic Lymphohistiocytosis
Interventions: DRUG: L-DEP and PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypnosis for Pain in Black Women With Advanced Breast Cancer: A Feasibility Study
Status: WITHDRAWN
Conditions: Breast Cancer|Inflammatory Breast Cancer Stage IV|Inflammatory Breast Neoplasms|Triple Negative Breast Neoplasms|Neoplasm Metastasis
Interventions: BEHAVIORAL: Self-Administered Hypnosis|BEHAVIORAL: Self-Administered White Noise Hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Daily, Long-Term Intermittent Fasting for the Prevention of PSA-Recurrence in Patients With Localized Prostate Cancer After Radical Prostatectomy
Status: WITHDRAWN
Conditions: Stage I Prostate Cancer AJCC v8|Stage II Prostate Cancer AJCC v8|Stage IIA Prostate Cancer AJCC v8|Stage IIB Prostate Cancer AJCC v8|Stage IIC Prostate Cancer AJCC v8|Stage III Prostate Cancer AJCC v8|Stage IIIA Prostate Cancer AJCC v8|Stage IIIB Prostate Cancer AJCC v8|Stage IIIC Prostate Cancer AJCC v8
Interventions: OTHER: Food Diary|OTHER: Preventative Dietary Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of Isotonic Solutions Versus Hypotonic Solutions for Preventing Hospital Acquired Hyponatremia
Status: COMPLETED
Conditions: Hyponatremia
Interventions: DRUG: 0.3% Saline in 3.3% dextrose|DRUG: 0.45% Saline in 5% dextrose|DRUG: 0.9% Saline in 5% dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oncolytic Adenovirus(H101) Combined With PD-1 Inhibitors in Patients With Advanced Malignant Pleural Mesothelioma
Status: RECRUITING
Conditions: Malignant Pleural Mesothelioma, Advanced
Interventions: DRUG: Oncolytic Adenovirus H101|DRUG: Programmed death receptor-1 inhibitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Biology and Treatment Strategy of AML in Its Subgroups: Multicenter Randomized Trial by the German Acute Myeloid Leukemia Cooperative Group (AMLCG)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|DRUG: Thioguanine|DRUG: Daunorubicin|DRUG: Cyclophosphamide|DRUG: G-CSF|PROCEDURE: Autologous stem cell transplantation|PROCEDURE: Allogeneic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Validation of the Management Process for Renal Anemia in Maintenance Hemodialysis Patients
Status: RECRUITING
Conditions: Anemia of Chronic Kidney Disease
Interventions: OTHER: Guiding treatment|OTHER: empirical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Clinical Effect of Palliative Treatment on Patients With Terminal Cancer
Status: COMPLETED
Conditions: Multidisciplinary Collaborative|Palliative Care Model|Quality of Life
Interventions: OTHER: Health education|OTHER: Comfort care|OTHER: Pain care|OTHER: Dietary care|OTHER: Psychological and social support care|OTHER: routine nursing intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Adding Different Drugs for Preventing Cough Induced by Bronchoscopic Spraying of Local Anesthetics
Status: RECRUITING
Conditions: Lung Diseases|Total Intravenous Anesthesia|Bronchoscopic Interventions
Interventions: PROCEDURE: bronchoscopic insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of IKERVIS® Eye Drops Once Daily on the Quality of Vision in Dry Eye Disease Patients With Severe Keratitis
Status: COMPLETED
Conditions: Keratitis
Interventions: DRUG: 1mg/mL ciclosporin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Tislelizumab Plus Chemotherapy for Resectable Thoracic Oesophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma|Neoadjuvant Chemoimmunotherapy|Adjuvant Therapy
Interventions: DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The AT-REBOA Target Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemorrhage|Shock, Traumatic|Cardiac Arrest Due to Trauma|Polytrauma
Interventions: PROCEDURE: Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: eCEASE to Support Treatment for Parental Tobacco Use
Status: ACTIVE_NOT_RECRUITING
Conditions: Tobacco Smoking|Second Hand Tobacco Smoke|Smoking Cessation
Interventions: BEHAVIORAL: iEHR + Navigator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Occurrence of Dyskalemia With Treatment for Hypertension
Status: COMPLETED
Conditions: Hypertension|Potassium Imbalance
Interventions: DRUG: Fixed Dose Combination pill of Telmisartan 40mg and Amlodipine 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Umbilical Cord Mesenchymal Stem Cell Transfusion in Decompensated Liver Cirrhosis
Status: UNKNOWN
Conditions: Decompensated Liver Cirrhosis
Interventions: BIOLOGICAL: UC-MSC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Filtration of Subarachnoid Hemorrhage Via Spinal Catheter
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage
Interventions: DEVICE: Spinal catheter insertion with extracorporeal filtration of CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Periarticular Multi-Drug Regimen on Pain After Partial Hip Replacement
Status: UNKNOWN
Conditions: Femoral Neck Fracture
Interventions: DRUG: periarticular injection of multidrug regimen|DRUG: none of medication preoperatively and intraoperatively
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ORSIRO Stents Versus Xience PRIME Stents Assessed by Optical Coherence Tomography
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DRUG: ORSIRO|DEVICE: XIENCE PRIME DES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Molecular Description of PKD1 and PKD2 Mutation Negative Carriers in ADPKD
Status: COMPLETED
Conditions: Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Interventions: OTHER: Blood Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dose-escalation Study to Evaluate the Safety and Tolerability of GS030 in Subjects With Retinitis Pigmentosa
Status: RECRUITING
Conditions: Non-syndromic Retinitis Pigmentosa
Interventions: COMBINATION_PRODUCT: Gene therapy: GS030-DP AND Medical device: GS030-MD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Prophylactic Antibiotics for Urethral Bulking
Status: RECRUITING
Conditions: Stress Urinary Incontinence|Postoperative Urinary Tract Infection|Urethral Bulking
Interventions: OTHER: Prophylactic antibiotics|OTHER: No antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Speed of Functional Recovery (Constant Score) Between Two Different Approaches of Humeral Nailing in Humeral Fractures: Through the Rotator Cuff or Through the Rotator Interval Split (HUNAAP)
Status: UNKNOWN
Conditions: Humeral Upper Extremity Fracture|Humeral Diaphysis Fracture
Interventions: PROCEDURE: Humeral neailling in humeral fractures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety as Mono or Combination Therapies With Anti-diabetes Mellitus Drugs in Japanese Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type2 Diabetes|High Blood Sugar
Interventions: DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)
Status: SUSPENDED
Conditions: Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)
Interventions: DRUG: P1446A-05
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INB03 for the Treatment of Pulmonary Complications From COVID-19
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: INB03|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MRI/Ultrasound Fusion Guided Laser Ablation of Prostate Cancer
Status: RECRUITING
Conditions: Neoplasms Prostate|Cancer of the Prostate
Interventions: DEVICE: Image Fusion (MR/US) Software Registration Guided Laser Ablation of Prostate Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nimotuzumab in Combination With TPF(Cisplatin ,Fluorouracil and Docetaxel) for Head and Neck Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Chemotherapy|DRUG: Nimotuzumab and Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Viral TCR Gene Therapy
Status: WITHDRAWN
Conditions: Endocrine/Neuroendocrine|Non-Small Cell Lung Cancer|Breast Cancer|Gastrointestinal/Genitourinary Cancers|Ovarian Cancer
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Aldesleukin|BIOLOGICAL: Sleeping Beauty Transposed PBL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eletriptan for the Treatment of Migraine in Patients With Previous Poor Response or Tolerance to Oral Sumatriptan
Status: COMPLETED
Conditions: Migraine With or Without Aura
Interventions: DRUG: Placebo|DRUG: Eletriptan 40 mg|DRUG: Eletriptan 80 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Fish Oils on Inflammation and Insulin Resistance
Status: COMPLETED
Conditions: Metabolic Syndrome|Insulin Resistance
Interventions: DRUG: omega-3 fatty acid|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Adjunctive Ventricular Arrhythmia Suppression Trial (AVAST) Pilot
Status: COMPLETED
Conditions: Arrhythmia
Interventions: DRUG: Amiodarone Plus Ranolazine|DRUG: Amiodarone with Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Randomised Efficacy Study of Combination Antimalarials to Treat Uncomplicated Malaria
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Sulfadoxine-pyrimethamine|DRUG: Artesunate plus sulfadoxine-pyrimethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Effects of Intermittent Hypoxia on Restoring Hand Function Following SCI
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DRUG: Acute Intermittent Hypoxia (AIH)|OTHER: SHAM-Intermittent Room Air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management and Outcomes of Patients Admitted to Coronary Care Units, Depending on Degree of Frailty and Comorbidities
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocardial Infarction|Frailty
Interventions: DIAGNOSTIC_TEST: Clinical Frailty Scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 68Ga-FAPI PET/CT for the Detection of Adenoid Cystic Carcinoma(ACC)
Status: UNKNOWN
Conditions: 68Ga-FAPI PET/CT|Metastatic Adenoid Cystic Carcinoma
Interventions: DRUG: 68Ga-FAPI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetic, Safety, Tolerability and Immunogenicity Study of SB2 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: SB2|BIOLOGICAL: EU Remicade|BIOLOGICAL: US Remicade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Nilotinib 800 Mg And Imatinib 800 Mg For The Treatment Of Patients With Gastrointestinal Stromal Tumors (Gist) Refractory To Imatinib 400 Mg
Status: TERMINATED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Nilotinib|DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy People to Compare 2 Different Formulations of BI 1015550 Taken With or Without Food
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1015550 ICF|DRUG: BI 1015550 TF2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Initial Efficacy Study of Supporting Play, Exploration, & Early Development Intervention
Status: COMPLETED
Conditions: Infant, Premature, Diseases|Brain White Matter Disease Periventricular
Interventions: BEHAVIORAL: SPEEDI Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of PRP Injection After Arthroscopic Meniscal Repair in the Healing Process
Status: COMPLETED
Conditions: Knee Pain|Knee Injuries
Interventions: BIOLOGICAL: platelet rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analgesic Efficacy of Intravenous Acetaminophen After Video-assisted Thoracic Surgery
Status: COMPLETED
Conditions: Lung Tumor
Interventions: DRUG: IV Acetaminophen|DRUG: Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Feasibility Study of a Cognitive Behavioral Coping Skills (CBCS) Group Intervention for Hep C Therapy Patients
Status: COMPLETED
Conditions: Hepatitis C|Hepatitis C, Chronic
Interventions: BEHAVIORAL: Cognitive Behavior Coping Skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Modulation of Immune Receptors to Enhance the Response to Dendritic Cell Vaccination in Metastatic Melanoma
Status: TERMINATED
Conditions: Metastatic Melanoma
Interventions: BIOLOGICAL: Vaccination with RNA-transfected mature autologous DC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose:
Clinical trial: A Ph2b to Evaluate Clinical Efficacy and Safety of Tildacerfont in Adult CAH
Status: TERMINATED
Conditions: Congenital Adrenal Hyperplasia
Interventions: DRUG: Tildacerfont/Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sensitivity of Fecal Immunochemical Test (FIT) for Colorectal Cancer (CRC) Screening
Status: COMPLETED
Conditions: Colorectal Neoplasms Malignant|Colonoscopy|Early Detection of Cancer|Female|Mass Screening|Middle Aged|Occult Blood
Interventions: DIAGNOSTIC_TEST: Positive fecal immunochemical test (FIT)|DIAGNOSTIC_TEST: Negative fecal immunochemical test (FIT)|DIAGNOSTIC_TEST: Fecal immunochemical test (FIT) not performed
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate Efficacy, Safety and Tolerability of HM15211 in Subjects
Status: RECRUITING
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: HM15211|DRUG: Placebo of HM15211
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pediatric Lead Extractability and Survival Evaluation (PLEASE)
Status: TERMINATED
Conditions: Ventricular Tachycardia|Ventricular Fibrillation|Cardiomyopathy|Long QT Syndrome|Congenital Heart Disease
Interventions: DEVICE: ICD lead implant|DEVICE: Thin leads
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Sunscreen Based on Bioadhesive Nanoparticles
Status: COMPLETED
Conditions: Melanoma|UV Ray Skin Damage
Interventions: DRUG: Standard Sunscreen|DEVICE: BNP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Miravirsen in Combination With Telaprevir and Ribavirin in Null Responder to Pegylated-Interferon Alpha Plus Ribavirin Subjects With Chronic Hepatitis C Virus Infection
Status: UNKNOWN
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Miravirsen|DRUG: Telaprevir|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 6 Month Safety Study Of Ciclesonide Nasal Aerosol (Zetonna®) And Ciclesonide Nasal Spray (Omnaris®) In Subjects 12 Years And Older With Perennial Allergic Rhinitis (PAR)
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: ciclesonide nasal aerosol|DRUG: ciclesonide nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effectiveness of Two Different Dosages of Cortisone Compared to Placebo in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Progression of Rheumatoid Arthritis
Interventions: DRUG: Prednisolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Buffered Local Anesthesia in Dental Extraction.
Status: UNKNOWN
Conditions: Anesthesia, Local
Interventions: DRUG: sodium bicarbonate 8.4%|DRUG: 2%lidocaine with 1:80.000 epinphrine|DEVICE: Mixing pen (onset buffering system)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fixed Dose Spinal Bupivacaine for Cesarean Delivery
Status: COMPLETED
Conditions: Spinal Anesthesia|Cesarean Section
Interventions: DRUG: Fixed dose of 12.5mg bupivacaine|DRUG: Height-adjusted dose of bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Participants With Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: JNJ-68284528|DRUG: Lenalidomide|DRUG: Daratumumab|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Timing Matter? Supporting Play, Exploration, and Early Developmental Intervention
Status: ACTIVE_NOT_RECRUITING
Conditions: Preterm Infant|Cerebral Palsy
Interventions: BEHAVIORAL: Supporting Play Exploration and Developmental Intervention (SPEEDI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: dMR During First Line Treatment of Non Squamous Lung Cancer: Time Course and Prognostic and Predictive Impact.
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DEVICE: dMRT|DRUG: Bevacizumab|DRUG: paclitaxel and carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Irreversible Electroporation(IRE) For Unresectable Stomach Neoplasms
Status: COMPLETED
Conditions: Stomach Neoplasms
Interventions: PROCEDURE: Irreversible electroporation (IRE)|DEVICE: NanoKnife
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Learn How Well Linvoseltamab Works Compared to the Combination of Elotuzumab, Pomalidomide and Dexamethasone for Adult Participants With Relapsed/Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Relapsed Refractory Multiple Myeloma (RRMM)
Interventions: DRUG: Linvoseltamab|DRUG: Elotuzumab|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of Maintenance Systemic Therapy After Radiation for Oligometastatic Renal Cell Carcinoma (ASTROs)
Status: RECRUITING
Conditions: Oligometastatic Renal Cell Carcinoma
Interventions: DRUG: Pembrolizumab|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety of VB6-845 in Patients With Advanced Solid Tumours of Epithelial Origin
Status: TERMINATED
Conditions: Neoplasms, Glandular and Epithelial
Interventions: DRUG: VB6-845
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cabazitaxel and Abiraterone Acetate in Patients With Metastatic Castrate-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Cabazitaxel XRP6258|DRUG: Abiraterone acetate|DRUG: Prednisone 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety of Using Buprenorphine With Naloxone in a Buccal Film to Initiate Treatment of Opioid Dependent Subjects
Status: WITHDRAWN
Conditions: Opioid Dependence
Interventions: DRUG: BEMA Buprenorphine NX|DRUG: Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of DTaP-IPV-Hep B-PRP~T Combined Vaccine to CombAct-HIB® Concomitantly Given With Engerix B® Paediatric and OPV
Status: COMPLETED
Conditions: Hepatitis B|Polio|Diphtheria|Pertussis|Haemophilus Influenzae Type b
Interventions: BIOLOGICAL: DTaP-IPV-HB-PRP~T|BIOLOGICAL: CombAct-HIB®|BIOLOGICAL: Engerix B® Pediatric
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Oral Metformin for Treatment of ABCA4 Retinopathy
Status: RECRUITING
Conditions: ABCA4 Retinopathy|Stargardt Disease|Retinal Dystrophy|Retinal Degeneration
Interventions: DRUG: Metformin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Surufatinib Plus Sintilimab Combined With Chemotherapy in Gastric/Gastroesophageal Junction Adenocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer|Gastro Esophageal Junction Cancer
Interventions: DRUG: Surufatinib|DRUG: Sintilimab|DRUG: Oxaliplatin|DRUG: S1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scalp Blocks Effect on Postoperative Nausea & Vomiting After Craniotomy
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: PROCEDURE: Scalp block|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Erlotinib and Docetaxel in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) After Failure of One Chemotherapy Regimen
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Docetaxel and Erlotinib|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STOP-AUST: The Spot Sign and Tranexamic Acid On Preventing ICH Growth - AUStralasia Trial
Status: COMPLETED
Conditions: Intracerebral Haemorrhage|Stroke
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Cost Effectiveness of STEADI
Status: COMPLETED
Conditions: Accidental Fall
Interventions: BEHAVIORAL: Gait and balance assessment|BEHAVIORAL: Medication review|BEHAVIORAL: Comorbidity review|BEHAVIORAL: Fall history|BEHAVIORAL: Assessment of feet/footwear|BEHAVIORAL: Assessment of visual acuity|BEHAVIORAL: Home safety risk assessment|BEHAVIORAL: Vitamin D Deficiency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Be Sweet to Toddlers: Does Sugar Water Reduce Pain During Blood Work?
Status: TERMINATED
Conditions: Pain Due to Certain Specified Procedures
Interventions: DRUG: 24% sucrose|DRUG: Sterile water|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PECS I Block for Breast Subpectoral Implant Surgery
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Ropivacaine (PECS bloc)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Nursing Home Care Through Feedback On PerfoRMance Data
Status: COMPLETED
Conditions: Organizational Context
Interventions: OTHER: Initial face-to-face dissemination workshop|OTHER: Face-to-face goal setting workshop|OTHER: Virtual support workshops|OTHER: Face-to-face support workshops|OTHER: On-demand email and telephone support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Pulses Through the Gut Microbiome and Bioavailability of Bioactive Compounds
Status: RECRUITING
Conditions: Lifestyle-related Condition
Interventions: OTHER: Pulses diet|OTHER: Plant proteins diet|OTHER: Habitual diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Filgrastim Plus Chemotherapy Compared With Filgrastim Alone In Treating Women Undergoing Peripheral Stem Cell Transplantation For Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Filgrastim (G-CSF)|DRUG: Carmustine|DRUG: Cisplatin|DRUG: Cyclophosphamide (CTX)|DRUG: Etoposide|DRUG: Thiotepa|PROCEDURE: Peripheral Blood Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PTX-COVID19-B, an mRNA Humoral Vaccine, is Intended for Prevention of COVID-19 in a General Population. This Study is Designed to Evaluate Safety, Tolerability, and Immunogenicity of PTX-COVID19-B Vaccine in Healthy Seronegative Adults Aged 18-64
Status: COMPLETED
Conditions: Covid19 Vaccine
Interventions: BIOLOGICAL: PTX-COVID19-B|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Compare Bleeding Risk Between Cold and Hot Snaring Polypectomy for Small Colorectal Polyp: a Randomized Control Trial
Status: COMPLETED
Conditions: Colorectal Polyp
Interventions: DEVICE: Polypectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of HuCNS-SC Cells in Patients With Infantile or Late Infantile Neuronal Ceroid Lipofuscinosis (NCL)
Status: COMPLETED
Conditions: Neuronal Ceroid Lipofuscinosis
Interventions: PROCEDURE: Surgery to implant human CNS stem cells (HuCNS-SC)|DRUG: Medication to suppress the immune system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine as Adjuvant in Erector Spinae Plane Block After Shoulder Arthroscopy
Status: COMPLETED
Conditions: Arthroscopy|Erector Spinae Plane Block|Analgesia
Interventions: PROCEDURE: Erector Spinae Plane block without Dexmedetomidine group|PROCEDURE: Erector Spinae Plane block with Dexmedetomidine group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eyelash Prostheses Compared to 5.0% Lifitegrast BID for Dry Eye Disease.
Status: UNKNOWN
Conditions: Dry Eye
Interventions: DEVICE: Eyelash prostheses|DEVICE: 5.0% Lifitegrast Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azacytidine and Bortezomib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: DRUG: Vidaza|DRUG: Velcade
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stress Test in Detecting Heart Damage in Premenopausal Women With Stage I-III Breast Cancer
Status: COMPLETED
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Premenopausal|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions: BIOLOGICAL: Adenosine|PROCEDURE: Magnetic Resonance Imaging|DRUG: Regadenoson|PROCEDURE: Stress Management Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Supported Employment in Patient Aligned Care Teams
Status: COMPLETED
Conditions: Mental Disorder|Substance Use Disorders|Posttraumatic Stress Disorder|Major Depressive Disorder|Anxiety Disorder
Interventions: BEHAVIORAL: Individual Placement and Support (IPS)|OTHER: Treatment as Usual Vocational Rehabilitation/Transitional Work (TUA-VR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib in Combination With Temozolomide in Treating Relapsed/Recurrent/Refractory Pediatric Solid Tumors
Status: WITHDRAWN
Conditions: Glioma|Rhabdomyosarcoma|Osteosarcoma|Medulloblastoma|Neuroectodermal Tumor|Ependymoma|Ewing's Sarcoma|Wilms Tumor
Interventions: BIOLOGICAL: Erlotinib|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diarrhea and Bivalent Oral Polio Vaccine Immunity
Status: COMPLETED
Conditions: Seroimmunity|Diarrhea|Polio
Interventions: BIOLOGICAL: bivalent oral polio vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Medical Assistant Health Coaching in Primary Care for Patients With Chronic Conditions
Status: COMPLETED
Conditions: Diabetes|Hypertension|Hyperlipidemia
Interventions: BEHAVIORAL: Health coaching by medical assistants in primary care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Clasic Laryngeal Mask Airway(C-LMA) and I-gel Releated Regurgitation and Complications
Status: UNKNOWN
Conditions: Bladder Tumour|Prostate Hyperplasia
Interventions: DEVICE: i-gel|DEVICE: C-LMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Feasibility and Safety of Acupuncture in the Prevention of Late Irinotecan-related Diarrhea in Pediatric Patients
Status: COMPLETED
Conditions: Pediatric Cancer|Solid Tumor
Interventions: OTHER: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Explorative Psoriasis Biomarker Study
Status: UNKNOWN
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Guselkumab|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nebulized MgSO4 in Persistent Pulmonary Hypertension of Newborn
Status: COMPLETED
Conditions: Persistent Fetal Circulation|Persistent Pulmonary Hypertension of the Newborn|PPHN
Interventions: DRUG: Nebulized Magnesium Sulfate|DRUG: Intravenous Magnesium Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Coagulopathy in Patients Undergoing Cytoreductive Surgery and HIPEC Intraperitoneal Chemotherapy (HIPEC)
Status: COMPLETED
Conditions: Coagulation Disorder|Carcinomatosis
Interventions: DIAGNOSTIC_TEST: ROTEM parameters, platelet function assay (PFA-100), von Willebrand and Factor XIII
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety Study of JNJ-56021927 in Participants With Metastatic Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms, Castration-Resistant
Interventions: DRUG: JNJ-56021927
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Multiple Perforations of the Sinus Floor on Bone Formation After Sinus Floor Elevation
Status: RECRUITING
Conditions: Sinus Elevation|Dental Implant|Bone Formation
Interventions: PROCEDURE: perforation of the sinus floor|PROCEDURE: no perforation of the sinus floor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Temperature Management
Status: COMPLETED
Conditions: Hypothermia
Interventions: DEVICE: Intraoperative warming (Bair Hugger)|DEVICE: Pre- and intraoperative warming (HotDog)|DEVICE: Intraoperative warming (HotDog)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Celecoxib in Preventing the Damaging Effects of Sunburn in Healthy Volunteers
Status: COMPLETED
Conditions: No Evidence of Disease
Interventions: PROCEDURE: UV Light Therapy|OTHER: Placebo|DRUG: Celecoxib|PROCEDURE: Biopsy|OTHER: Imaging Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Adjunctive Biofeedback Intervention for Operation Iraqi Freedom/Operation Enduring Freedom (OIF-OEF) Post Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Post-traumatic Stress Disorder
Interventions: DEVICE: StressEraser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study of the Efficacy and Safety of Luliconazole Cream in Tinea Pedis (Athlete's Foot)
Status: COMPLETED
Conditions: Tinea Pedis
Interventions: DRUG: Luliconazole Cream 1% - 2 wks|DRUG: Placebo Comparator -2 wks|DRUG: Luliconazole Cream 1% - 4 wks|DRUG: Placebo Comparator - 4 wks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Death to Onchocerciasis and Lymphatic Filariasis (DOLF) Triple Drug Therapy for Lymphatic Filariasis
Status: COMPLETED
Conditions: Lymphatic Filariasis
Interventions: DRUG: 3 drug dose - IDA|DRUG: 2 drug dose - DA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Schroth Exercise Versus Functional Electrical Stimulation in Adolescent With Spinal Deformities
Status: COMPLETED
Conditions: Idiopathic Spinal Deformities
Interventions: OTHER: Schroth Exercise|OTHER: Functional Electrical Stimulation (physiotherapy techniques)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fast Magnetic Resonance Imaging as Compared to Computed Tomography Scan in Pediatric Orbital Cellulitis Imaging
Status: UNKNOWN
Conditions: Orbital Cellulitis
Interventions: DEVICE: Computed Tomography Scan|DEVICE: Fast Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Processing of Salient Emotional Stimuli as a Function of Tetrahydrocannabinol (THC) and Cannabidiol (CBD)
Status: COMPLETED
Conditions: Healthy Humans
Interventions: DRUG: tetrahydrocannabinol|DRUG: cannabidiol|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Sun Protection Factor 30 Persistence Between Inorganic and Organic Sunscreen in Swimmer
Status: UNKNOWN
Conditions: Sunscreen Persistence
Interventions: OTHER: Inorganic sunscreen|OTHER: Organic sunscreen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Temocillin Versus a Carbapenem as Initial Intravenous Treatment for ESBL Related Urinary Tract Infections
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DRUG: Temocillin|DRUG: meropenem or imipenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Study for the "Jockey Club E-Generation: Impact Extension Project for Chronic Knee Pain Management"
Status: RECRUITING
Conditions: Knee Discomfort|Knee Pain Chronic
Interventions: OTHER: 12-week intervention|OTHER: 12-week attention control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION