pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety of Parecoxib on Morphine Patient-controlled Epidural Analgesia (PCEA) After Gynecologic Surgery
Status: COMPLETED
Conditions: Benign Female Reproductive System Neoplasm
Interventions: DRUG: Parecoxib Sodium|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of Gene Therapy Drug in the Treatment of Primary Hypertriglyceridemic Patients With Recurrent Pancreatitis
Status: NOT_YET_RECRUITING
Conditions: Hypertriglyceridemia, Familial
Interventions: GENETIC: GC304
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement of Eye Blood Flow and Renal Function in Healthy and Diabetic Patients
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Captopril|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Normative Values for the German Version of the Montreal Cognitive Assessment (MoCA)
Status: COMPLETED
Conditions: Cognitive Impairment|Cognitive Decline|Cognition Disorders|Cognitive Symptom|Cognitive Change|Cognitive Deterioration|Cognitive Abnormality|Cognitive Impairment, Mild|Cognition Disorders in Old Age|Dementia|Dementia Alzheimers|Dementia, Alzheimer Type|Dementia, Mild|Dementia of Alzheimer Type
Interventions: DIAGNOSTIC_TEST: MoCA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Atrial FIbrillation Treatment With Cryoballoon in Heart failurE (AFICHE)
Status: UNKNOWN
Conditions: Atrial Fibrillation|Heart Failure, Systolic
Interventions: PROCEDURE: Cryoballoon ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficiency of the Chronic Pain Management Training Program
Status: COMPLETED
Conditions: Nursing Caries|Chronic Pain
Interventions: OTHER: chronic pain management education program|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Assess the Safety and Pharmacokinetics of Multiple Ascending Subcutaneous Doses of DS-2325a in Healthy Subjects
Status: COMPLETED
Conditions: Netherton Syndrome
Interventions: DRUG: DS-2325a|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Congenital Lung Anomalies (CLA) Swiss Database
Status: RECRUITING
Conditions: Congenital Lung Malformation|Congenital Lung Cyst|Sequestrum|Bronchogenic Cancer|Pleuropulmonary Blastoma|Acinar Dysplasia
Interventions: PROCEDURE: Malformations resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: National Bacterial Meningitis Study
Status: RECRUITING
Conditions: Meningitis|Children, Only|Pneumococcal Conjugate Vaccine|Meningococcal Vaccines|H. Influenzae Vaccine|Neonatal Infection|Antibiotic Treatment|Case Fatality Rate
Interventions: OTHER: observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Experimental Pain Reporting Accuracy and Clinical Post-operative Pain
Status: UNKNOWN
Conditions: Surgical Procedure, Unspecified|Pain, Postoperative|Ear, Nose, and Throat (ENT) Disease
Interventions: DEVICE: pain reporting accuracy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Manganese-Enhanced Magnetic Resonance Imaging of the Myocardium
Status: COMPLETED
Conditions: Ischemic Cardiomyopathy|Dilated Cardiomyopathy|Hypertrophic Cardiomyopathy
Interventions: OTHER: Mangafodipir trisodium
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Moringa Oleifera Mouthwash
Status: UNKNOWN
Conditions: Orthodontic Appliance Complication
Interventions: OTHER: Moringa Oleifera Mouthwash|OTHER: Placebo Mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Personalized Electroacupuncture Treatment for Chemotherapy-induced Nausea and Vomiting in Breast Cancer (PET)
Status: RECRUITING
Conditions: Cancer
Interventions: PROCEDURE: True acupuncture + standard antiemetic treatment|PROCEDURE: Sham acupuncture + standard antiemetic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Machine Learning Characterization of Solid Tumors
Status: RECRUITING
Conditions: Adenocarcinoma of Prostate|Radical Prostatectomy|Hepatocellular Carcinoma (HCC)|Glioma|Renal Cell Carcinoma (RCC)|Prostate Cancer
Interventions: DRUG: [18F]DCFPyL|RADIATION: PET/MRI scanner
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HPV Integration and Tumorigenesis of Uterine Cervical Adenocarcinoma
Status: UNKNOWN
Conditions: Cervical Adenocarcinoma|Human Papillomavirus|Genome-wide Association Study|Whole Exome Sequencing|Transcriptome|Metabolome|Tumorigenesis|Prognosis
Interventions: COMBINATION_PRODUCT: A multi-omics analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Recovery of Muscle Function After Deep Neuromuscular Block by Means of Diaphragm Ultrasonography
Status: UNKNOWN
Conditions: Post-operative Residual Curarization
Interventions: DRUG: Sugammadex|DEVICE: Diaphragm Ultrasonography|DRUG: Neostigmine|DRUG: Atropine|DEVICE: Neurumuscual monitoring|DRUG: Rocuronium|DRUG: Fentanyl|DRUG: Propofol|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate NBI-921352 as Adjunctive Therapy in Subjects With SCN8A Developmental and Epileptic Encephalopathy Syndrome (SCN8A-DEE)
Status: RECRUITING
Conditions: SCN8A Developmental and Epileptic Encephalopathy Syndrome
Interventions: DRUG: NBI-921352|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CBT for African Americans With Cognitive Impairment
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: BEHAVIORAL: Group-based Cognitive Behavioral Therapy (CBT)|BEHAVIORAL: Phone-based Cognitive Behavioral Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effects of Topical Herbal Medicine -Rhubarb Ointment on Rosacea
Status: UNKNOWN
Conditions: Rosacea|Chinese Herbal Medicine
Interventions: DRUG: dian dao san
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SMC021A - Absorption, Efficacy and Tolerance in Patients With Osteoarthritis. A Placebo-Controlled 14-Days Study
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Oral salmon calcitonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Single Dose Extended Release Naproxen Sodium (660 mg) Tablet Versus Naproxen Sodium (220 mg) Tablet Three Times Daily
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Naproxen Sodium ER (BAY117031), 20% HPMC|DRUG: Naproxen Sodium ER (BAY117031), 30% HPMC|DRUG: Naproxen Sodium ER (BAY117031), 40% HPMC|DRUG: Aleve (Naproxen Sodium, BAY117031)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Obesity-derived Cytokines on Protein Turnover and Carbohydrate Metabolism in Human Skeletal Muscle
Status: COMPLETED
Conditions: Obesity|Sarcopenia
Interventions: DRUG: Pioglitazone|DRUG: Insulin|DRUG: Octreotide|DRUG: Glucose|DRUG: Mixed Amino Acids|OTHER: [2H5]phenylalanine|OTHER: [1-13C]leucine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Oral Probiotic Supplementation on The Rate of Hospital Acquired Infection and Necrotizing Enterocolitis in Preterm Very Low Birth Weight Infants
Status: COMPLETED
Conditions: Nosocomial Infection|Necrotizing Enterocolitis
Interventions: BIOLOGICAL: probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of Rotarix TM in Taiwanese Infants Who Received Hepatitis B Immunoglobulin After Birth.
Status: COMPLETED
Conditions: Infections, Rotavirus
Interventions: BIOLOGICAL: Rotarix TM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Incorporating Mind-body Skills With Diabetes Education in Adolescents With Type 1 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 1 Diabetes|Adolescent Behavior
Interventions: BEHAVIORAL: Mind-body skills|BEHAVIORAL: Diabetes education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodialysis Infection Prevention Using Polysporin Ointment With Shower Technique in Satellite Centres Pilot Study
Status: UNKNOWN
Conditions: End Stage Renal Failure on Dialysis
Interventions: OTHER: Shower Technique Protocol|OTHER: Standard CVC Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Rapid Intermittent Compared With Slow Continuous Correction in Severe Hyponatremia Patients
Status: COMPLETED
Conditions: Hyponatremia Symptomatic
Interventions: DRUG: 3% hypertonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Activity and Cardiovascular Risk
Status: NOT_YET_RECRUITING
Conditions: Rheumatoid Arthritis|Chronic Kidney Diseases|Endothelial Dysfunction|Arterial Stiffness|Exercise
Interventions: OTHER: Training group|OTHER: Physical activity orientation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Variable PSV in Acute Lung Injury: Part I and Part II
Status: COMPLETED
Conditions: Acute Lung Injury (ALI)|Acute Distress Respiratory Syndrome (ARDS)
Interventions: OTHER: Noisy-PSV 1|OTHER: Noisy-PSV 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: D2 Dopamine Receptor Occupancy After Oral Dosing of Lu AF35700 in Healthy Men Using [11C]-PHNO as Tracer Compound
Status: COMPLETED
Conditions: Healthy Men
Interventions: DRUG: Part A: Lu AF35700|DRUG: Part B: Lu AF35700
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Cognitive Therapy and Exposure Therapy in Individuals With Hypochondriasis
Status: COMPLETED
Conditions: Hypochondriasis|Somatoform Disorders
Interventions: BEHAVIORAL: Psychotherapy (CT or ET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Faslodex Advanced Breast Cancer Local Chinese Study
Status: COMPLETED
Conditions: Advanced Breast Cancer
Interventions: DRUG: Fulvestrant|DRUG: Anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sex-related Differences in Sympathetic Vascular Transduction in the Setting of Hypoxemia
Status: RECRUITING
Conditions: Vasodilation|Hypoxia
Interventions: DRUG: Propranolol Pill|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Balanced and Sustainable Diet Application for Insulin Resistance and Inflammation Marker of Obese People
Status: COMPLETED
Conditions: Obesity|Insulin Resistance|Inflammation|Blood Glucose, High
Interventions: OTHER: balanced and sustainable diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Threat Reversal Abnormality in Patients With Anxiety Disorders
Status: NOT_YET_RECRUITING
Conditions: Anxiety Disorder|Anxiety State
Interventions: DEVICE: Active repetitive deep transcranial magnetic stimulation (dTMS)|DEVICE: Sham repetitive deep transcranial magnetic stimulation (dTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab, Cladribine, and Temsirolimus in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: cladribine|DRUG: temsirolimus|BIOLOGICAL: Filgrastim|BIOLOGICAL: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rose Geranium in Sesame Oil Nasal Spray for the Improvement of Nasal Vestibulitis Symptoms in Cancer Patients Receiving Chemotherapy
Status: COMPLETED
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm|Nasal Vestibulitis
Interventions: DRUG: Placebo Administration|OTHER: Questionnaire Administration|DRUG: Rose Geranium in Sesame Oil Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Inflammation in COPD and the Effect of Nicotinamide Riboside
Status: COMPLETED
Conditions: COPD
Interventions: DIETARY_SUPPLEMENT: Nicotinamide Riboside|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Apneic Oxygénation by Nasal Canula During Infants Airway Management Study
Status: UNKNOWN
Conditions: Infant Apnea|Surgical Procedure, Unspecified|Airway Management
Interventions: DEVICE: High Flow nasal Cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Analgesic Effect of Ketamine Vs Ketamine Magnesium Infusion and Their Effect on Postoperative Morphine Consumption
Status: COMPLETED
Conditions: Nephrectomy
Interventions: DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating The Safety And Pharmacokinetics Of Escalating Doses Of RO7297089 In Patients With Relapsed Or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Refractory Multiple Myeloma|Relapsed Multiple Myeloma
Interventions: DRUG: RO7297089
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Geniculate Artery Embolization for Osteoarthritis
Status: RECRUITING
Conditions: Osteo Arthritis Knee|Arthritis|Osteoarthritis|Osteoarthritis, Knee
Interventions: DEVICE: Geniculate Artery Embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: M6620 and Carboplatin With or Without Docetaxel in Treating Patients With Metastatic Castration-Resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Prostate Carcinoma|Stage IV Prostate Cancer AJCC v8
Interventions: DRUG: Berzosertib|DRUG: Carboplatin|DRUG: Docetaxel|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TTFields Together With Temozolomide and Radiotherapy in Patients With Newly Diagnosed GBM
Status: UNKNOWN
Conditions: Glioblastoma Multiforme
Interventions: DEVICE: NovoTTF-200A|RADIATION: Radiotherapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lower Extremity Elevation to Minimize Hemodynamic Instability During Induction of General Anesthesia
Status: NOT_YET_RECRUITING
Conditions: Post Induction Hypotension
Interventions: PROCEDURE: Group 1: LEE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Botulinum Toxin Injection Into Epicardial Fat Pads to Prevent Atrial Fibrillation in Patients Undergoing Cardiac Surgery
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: BIOLOGICAL: botulinum toxin injection|BIOLOGICAL: 0.9% normal saline injection|DEVICE: Implantable loop recorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib With Irinotecan in Metastatic Colorectal Cancer (mCRC) and K-RAS Mutation
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Nexavar (Sorafenib) and irinotecan (Campto)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidemiological Study of Seroprevalence Against the SARS-CoV-2 Virus (COVID-19)
Status: COMPLETED
Conditions: Coronavirus Infection|Prevalence
Interventions: BIOLOGICAL: Anti-SARS-CoV-2 IgT seropositivity
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effects of Active Release Technique (ART) on Pectoralis Minor Tightness in Post Mastectomy Women.
Status: COMPLETED
Conditions: Postgastrectomy Syndrome
Interventions: OTHER: active release group|OTHER: active control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chest Wall Muscle Stretching and Acute Effects in Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: PROCEDURE: Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Probiotic Lozenges on White Spot Lesion Development in Orthodontic Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: White Spot Lesion
Interventions: DIETARY_SUPPLEMENT: Biogaia L. reuteri Prodentis® lozenges|DIETARY_SUPPLEMENT: Hersheyland Ice Breakers Mints sugar free lozenges
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Orally Administered Trimethoprim-sulfamethoxazole and Metronidazole as Prophylaxis of Infection Following Elective Colorectal Surgery
Status: COMPLETED
Conditions: Infection Prophylaxis in Colo Rectal Surgery
Interventions: DRUG: trimethoprim-sulfamethoxazole + metronidazole|DRUG: cefuroxime and metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Apatinib Mesylate (YN968D1) 1,000mg in Gastric Cancer Patient Failed to Standard Treatment
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Apatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Music Based Intervention (MBI) on Pain Response and Neurodevelopment in Preterm Infants
Status: COMPLETED
Conditions: Preterm Birth|Pain
Interventions: OTHER: Music Based Intervention|OTHER: Sham Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endovascular Treatment of Acute Ischemic Stroke With Underlying Intracranial Artery Stenosis
Status: RECRUITING
Conditions: Large Vessel Occlusion|Intracranial Artery Occlusion With Cerebral Infarction|Endovascular Treatments|Acute Ischemic Stroke
Interventions: DEVICE: balloon dilatation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gastroesophageal Reflux Disease After Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Gastroesophageal Reflux|Obesity
Interventions: PROCEDURE: Sleeve Gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Phase III Trial of ZD4054 (Zibotentan) (Endothelin A Antagonist) and Docetaxel in Metastatic Hormone Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Docetaxel|DRUG: ZD4054|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acid-Base Balance, Metabolism and Minerals
Status: COMPLETED
Conditions: Acid-Base Balance Disorder|Metabolic Acidosis
Interventions: DIETARY_SUPPLEMENT: alkaline salt mixture|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Appetite Regulation by Human Chemosignals From Tears and Plasma
Status: COMPLETED
Conditions: Obesity
Interventions: BIOLOGICAL: Sniffing emotional tears|BIOLOGICAL: Sniffing trickled saline|BIOLOGICAL: Sniffing fasting plasma|BIOLOGICAL: Sniffing postprandial plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Abuse Potential of Sativex
Status: COMPLETED
Conditions: Evaluation of Abuse Potential of Sativex
Interventions: DRUG: Sativex|DRUG: Sativex|DRUG: Sativex|DRUG: Placebo|DRUG: Marinol|DRUG: Marinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of OPC-41061 in Subjects With Cardiac-induced Edema (Congestive Heart Failure)
Status: COMPLETED
Conditions: Cardiac Edema
Interventions: DRUG: OPC-41061 （Tolvaptan)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Restless Leg Syndrome (RLS) Augmentation With Ecopipam, a D1 Specific Antagonist
Status: UNKNOWN
Conditions: Restless Legs Syndrome|Augmentation
Interventions: DRUG: Ecopipam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gene Transfer Clinical Study in X-Linked Myotubular Myopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: X-Linked Myotubular Myopathy
Interventions: GENETIC: Resamirigene bilparvovec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TQB3616 Capsules in the Treatment of Dedifferentiated Liposarcoma
Status: NOT_YET_RECRUITING
Conditions: Dedifferentiated Liposarcoma
Interventions: DRUG: TQB3616 capsule|DRUG: TQB3616 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Different Regimens of Colon Preparations for Advanced Cleaning.
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: (Macrogol 4000 52,500 g + Sodium sulphate anhydrous 3,750 g + Simethicone 0,080 g) full dose|DRUG: (Macrogol 4000 52,500 g + Sodium sulphate anhydrous 3,750 g + Simethicone 0,080 g) split dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Twelve -Month Study Observing How Insulin-naïve Patients With Type 2 Diabetes Mellitus Manage Diabetes Using Toujeo® After Oral Antidiabetic Drug Failure, the Side Effect of Toujeo®, and The Cost.
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: Insulin glargine (U300)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Two Different Treatment Methods
Status: COMPLETED
Conditions: Subacromial Impingement Syndrome|Musculoskeletal Diseases|Musculoskeletal Injury|Musculoskeletal Pain|Weakness, Muscle
Interventions: OTHER: Kinesiotaping|OTHER: Mulligan Mobilization Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NATRELLE® 410 X-Style and L-Style Breast Implants Continued Access Study
Status: TERMINATED
Conditions: Breast Augmentation|Breast Reconstruction|Breast Implant Revision
Interventions: DEVICE: Anatomically shaped, silicone-filled breast implants with low height/projection or extra-full projection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Vitamins and HAART in HIV Disease Progression
Status: COMPLETED
Conditions: HIV Infections
Interventions: DIETARY_SUPPLEMENT: Multivitamins (including B, C and E)|DIETARY_SUPPLEMENT: Multivitamins B, C and E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Influence of Ventilation on Perioperative Neurocognitive Disorders
Status: WITHDRAWN
Conditions: Cognitive Dysfunction
Interventions: OTHER: Hyperventilation|OTHER: Hypoventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability of Atezolizumab (ATZ) in Combination With Radium-223 Dichloride (R-223-D) in Metastatic Castrate-Resistant Prostate Cancer (CRPC) Progressed Following Treatment With an Androgen Pathway Inhibitor
Status: COMPLETED
Conditions: Castrate-Resistant Prostate Cancer
Interventions: DRUG: Atezolizumab|DRUG: Radium-223 Dichloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of Coagulation FVIIa (Recombinant) in Congenital Hemophilia A or B Patients With Inhibitors
Status: COMPLETED
Conditions: Hemophilia A With Inhibitors|Hemophilia B With Inhibitors
Interventions: BIOLOGICAL: Coagulation Factor VIIa (Recombinant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vasodilation Effect of Inhalational Anesthetics
Status: COMPLETED
Conditions: General Anesthesia
Interventions: DRUG: Halothane|DRUG: Isoflurane|DRUG: Sevoflurane|DRUG: Desflurane|DRUG: Enflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Stereotactic Body Radiotherapy (SBRT) With or Without Pembrolizumab (MK-3475) in Adults With Unresected Stage I or II Non-Small Cell Lung Cancer (NSCLC) (MK-3475-867/KEYNOTE-867)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: RADIATION: Stereotactic Body Radiotherapy (SBRT)|BIOLOGICAL: Pembrolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Pirtobrutinib With Venetoclax In Relapsed-Refractory MCL (Mantle Cell Lymphoma) Patients
Status: RECRUITING
Conditions: Mantle Cell Lymphoma|Non Hodgkin Lymphoma|Hematologic Malignancy
Interventions: DRUG: Pirtobrutinib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cinobufacini Tablets Combined With Chemotherapeutic Protocol in Treatment of Diffuse Large B Cell Lymphoma
Status: UNKNOWN
Conditions: Diffuse, Large B-Cell, Lymphoma
Interventions: DRUG: vindesine|DRUG: cyclophosphamide|DRUG: Epirubicin|DRUG: prednisone tablets|DRUG: Cinobufacini Tablets|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Xylitol on Oral Microbiota in Children
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: DIETARY_SUPPLEMENT: xylitol|DIETARY_SUPPLEMENT: sorbitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Interventions for Chronic Pain and Opioid-Related Problems
Status: COMPLETED
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Mindfulness-Oriented Recovery Enhancement|BEHAVIORAL: Supportive Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Minocycline in the Treatment of Drug-resistant Epilepsy in NORSE Patients
Status: ENROLLING_BY_INVITATION
Conditions: Epileptic Seizures Related to Drugs
Interventions: DRUG: minocycline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regional Erector Spinae Analgesic Block vs Standard of Care Undergoing Percutaneous Nephrolithotomy
Status: TERMINATED
Conditions: Kidney Stone|Surgery
Interventions: DRUG: 4mg PF Dexamethasone|DRUG: Control Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect of Local Pressure on Muscle Activity and General Relaxation in Persons With Hypertonia Following Stroke
Status: WITHDRAWN
Conditions: Deep Pressure|Muscle Activity|General Relaxation|Stroke|Hypertonia, Muscle
Interventions: DEVICE: constant deep pressure applied by an air splint|DEVICE: intermittent deep pressure applied by an air splint|DEVICE: uninflated air splint|OTHER: contralateral movement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacokinetics (PK), Pharmacodynamics (PD) and Safety of 2-Week Treatment With Inhaled AZD7594 in Adolescents (12 to 17 Years) With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: AZD7594
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Mirror-Based Virtual Reality Systems and Recalibration Software on Upper Extremity Function in Individuals Experiencing Hemiparesis Post-Stroke
Status: COMPLETED
Conditions: Stroke|Hemiparesis
Interventions: DEVICE: Virtual reality gaming
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Clinical Impact of Surgical Correction of Tricuspid Insufficiency in Implantable LVAD Patients
Status: RECRUITING
Conditions: Tricuspid Regurgitation|Heart Failure NYHA Class III|Heart Failure NYHA Class IV
Interventions: DEVICE: Left ventricular assist device (LVAD)|PROCEDURE: Tricuspid Valve Repair (TVR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antimullerian Hormone Versus Antral Follicle Count for Determination of Gonadotrophin Dosing in IVF
Status: COMPLETED
Conditions: Infertility
Interventions: OTHER: Serum AMH measurement|OTHER: AFC measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Early Versus Delayed Switch in Medication in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Duloxetine Hydrochloride|DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat in Combination With Chemoradiation in Locally Advanced HPV Negative HNSCC
Status: NOT_YET_RECRUITING
Conditions: HPV-Related Squamous Cell Carcinoma|Squamous Cell Carcinoma of the Oral Cavity|Squamous Cell Carcinoma of the Larynx|Squamous Cell Carcinoma of the Oropharynx|Squamous Cell Carcinoma of the Hypopharynx
Interventions: DRUG: Cisplatin|RADIATION: Radiation therapy|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Adjuvant Sintilimab in Hepatocellular Carcinoma With Microvascular Invasion
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sintilimab (9 cycles)|DRUG: Sintilimab (18 cycles)|OTHER: Active surveillance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide as Immune Adjuvant in Patient's With Chronic Lymphocytic Leukemia (CLL)
Status: TERMINATED
Conditions: Hematologic Disorder
Interventions: DRUG: Lenalidomide|BIOLOGICAL: Influenza Vaccine|BIOLOGICAL: Pneumovax Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: 1st Line Durvalumab in PS 2 NSCLC Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: NSCLC Stage IV|NSCLC Stage IIIB
Interventions: DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Intracoronary Administration of Fasudil in the Primary PCI of ST-segment-Elevation Myocardial Infarction
Status: UNKNOWN
Conditions: ST Segment Elevation Myocardial Infarction
Interventions: DRUG: Fasudil Hydrochloride|DRUG: Placebo saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Supplement Derived From Palm Oil on Cholesterol Levels and Chinese Red Yeast Rice in the Blood
Status: WITHDRAWN
Conditions: Cholesterol Lowering
Interventions: DRUG: Sugar Pill|DRUG: Chinese Red Yeast Rice (CRYR)|DRUG: CRYR + TRF|DEVICE: Tocotrienol-enriched Fraction of Palm Oil (TRF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accommodating Variable-Resistance Training in Patients With Juvenile Idiopathic Arthritis
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: OTHER: Accommodating variable-resistance training|OTHER: Standard physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modulation of Muscle Protein Metabolism by Essential Amino Acids
Status: UNKNOWN
Conditions: Old Age
Interventions: DIETARY_SUPPLEMENT: 15g Mixed Essential Amino Acids|DIETARY_SUPPLEMENT: 3g Leucine|DIETARY_SUPPLEMENT: 15g Mixed Essential Amino Acid REFEED
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Hemostatic Powder in Preventing Bleeding After Gastric Endoscopic Submucosal Dissection in High-risk Patients: A Prospective Randomized Control Study
Status: COMPLETED
Conditions: High-risk Patients for Post-ESD Bleeding
Interventions: PROCEDURE: Endo-clot™ (EndoClot Plus, Unc., Santa Clara, CA, USA) group|PROCEDURE: Hemostatic forceps Only (Coagrasper®, Olympus, Japan) group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Mechanical Intervention on the Scalp Microbiome: Setting the Stage for the Future Management of Cicatricial Alopecias
Status: TERMINATED
Conditions: Lichen Planopilaris of Scalp|Alopecia Areata
Interventions: DEVICE: Venus Glow
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial for Near Infrared Endoventricular Illumination for Neuroprotection in Very Early Cases of Parkinson's Disease (Ev-NIRT)
Status: RECRUITING
Conditions: Very Early Stage of Parkinson's Disease
Interventions: DEVICE: Ev-NIRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INdians Followed for INtensive Lipid Lowering Treatment and Its safetY
Status: TERMINATED
Conditions: Hypercholesterolemia
Interventions: DRUG: ezetimibe|DRUG: Comparator: Simvastatin 20, 40 and 80 mg|DRUG: Comparator: Atorvastatin|DRUG: Comparator: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Trial of Lenvatinib for the Treatment of Anaplastic Thyroid Cancer (ATC)
Status: TERMINATED
Conditions: Thyroid Carcinoma, Anaplastic
Interventions: DRUG: Lenvatinib 24 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing Uptake of Bowel Screening
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Suggested deadline for return of screening test|BEHAVIORAL: Planning sheet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intrinsic Foot Muscle Strengthening Interventions for Older Adults
Status: RECRUITING
Conditions: Accidental Fall
Interventions: OTHER: Intrinsic foot muscle strengthening exercises|OTHER: Minimal footwear with prescribed walking|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Augmented Reality in Polypectomy Skills Acquisition in Simulation-based Endoscopy Training
Status: RECRUITING
Conditions: Colonic Polyp
Interventions: OTHER: Augmented reality-based curriculum|OTHER: Conventional Simulation Curriculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of HQK-1001 in Patients With Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease|Sickle Cell Anemia|Sickle Cell Disorders|Hemoglobin S Disease|Sickling Disorder Due to Hemoglobin S
Interventions: DRUG: HQK-1001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Dose and Metformin for Vascular Health in Adults With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DRUG: Low Intensity Exercise + Metformin|DRUG: High Intensity Exercise + Metformin|DRUG: Low Intensity Exercise + Placebo|DRUG: High Intensity Exercise + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Interferon Alfa in Treating Patients With Newly Diagnosed Chronic Myelogenous Leukemia
Status: UNKNOWN
Conditions: Leukemia
Interventions: BIOLOGICAL: recombinant interferon alfa|DRUG: cytarabine|DRUG: hydroxyurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Does a Preoperative Bowel Regimen Change Time to First Bowel Movement After Robotic Sacral Colpopexy
Status: COMPLETED
Conditions: Constipation|Post-Op Complication
Interventions: DRUG: Polyethylene Glycol Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of iLivTouch and FibroScan for the Assessment of Liver Fibrosis and Steatosis in Adult Patients in the US
Status: RECRUITING
Conditions: Liver Fibrosis|Fatty Liver
Interventions: DEVICE: iLivTouch|DEVICE: FibroScan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Probiotics on Lipid Management
Status: UNKNOWN
Conditions: Primary Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Lactobacillus paracasei dietary supplement|OTHER: Placebo controls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial to Evaluate the Safety and Efficacy of DR-2041(Synthetic Conjugated Estrogens, A) for Treatment of Vulvovaginal Atrophy
Status: COMPLETED
Conditions: Menopause
Interventions: DRUG: DR-2041a|DRUG: DR-2041b|OTHER: Placebo|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Triple Pre-rehabilitation on Radiotherapy for Head and Neck Cancer Patients
Status: COMPLETED
Conditions: Triple Pre-rehabilitation|Radiotherapy|Head and Neck Cancer
Interventions: OTHER: triple pre-rehabilitation|OTHER: triple rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Chronic Thoracic and Neck and Upper Extremity Pain
Status: COMPLETED
Conditions: Back Pain|Neck Pain
Interventions: DRUG: Xylocaine|DRUG: Xylocaine and Celestone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aricept to Improve Functional Tasks in Vascular Dementia
Status: UNKNOWN
Conditions: Stroke|Vascular Dementia|Memory Deficits
Interventions: DRUG: Donepezil and self-generated memory training|DRUG: Donepezil and experimenter-administered memory training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab Plus Docetaxel and Capecitabine For First Line Treatment of Her2-Positive Advanced Gastric Cancer
Status: COMPLETED
Conditions: Stomach Neoplasms|Neoplasms Metastasis|ERBB2 Gene Amplification
Interventions: DRUG: Trastuzumab|DRUG: Docetaxel|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fruquintinib Plus Capecitabine as Maintenance Treatment of RAS / BRAF Wild-type Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: fruquintinib plus capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Strain-counterstrain on Ankle Instability
Status: TERMINATED
Conditions: Other Instability, Ankle and Foot
Interventions: OTHER: Strain Counterstrain|OTHER: Sham strain counterstrain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Digital Health Pathway for Children With Medical Complexity Requiring Tracheostomy
Status: NOT_YET_RECRUITING
Conditions: Tracheostomy
Interventions: PROCEDURE: Digital health pathway for children with medical complexity requiring tracheostomy (DECIDE-T)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Protein Quantity Within the USDA Healthy Style Eating Pattern on Sleep
Status: COMPLETED
Conditions: Sleep|Body Composition
Interventions: OTHER: Normal protein|OTHER: High protien
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of 3 Thalidomide Doses for the Treatment of Relapsed Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Thalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT