pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Safety and Efficacy of BCD-020 Comparing to MabThera in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide and Doxorubicin Hydrochloride Liposome in Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
Status: TERMINATED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: DRUG: Lenalidomide|DRUG: liposomal doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Stage III or Stage IV Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Adenocarcinoma|Endometrial Clear Cell Adenocarcinoma|Endometrial Serous Adenocarcinoma|Stage III Uterine Corpus Cancer|Stage IV Uterine Corpus Cancer
Interventions: DRUG: Doxorubicin Hydrochloride|DRUG: Cisplatin|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Intensity Focused Ultrasound Focal Ablation in Treating Patients With Progressive Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer|Sexual Dysfunction
Interventions: OTHER: laboratory biomarker analysis|OTHER: questionnaire administration|PROCEDURE: assessment of therapy complications|PROCEDURE: high-intensity focused ultrasound ablation|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peginesatide for Maintenance Treatment of Anemia in Participants on Hemodialysis
Status: COMPLETED
Conditions: Anemia|Chronic Kidney Disease|Chronic Renal Failure
Interventions: DRUG: peginesatide|DRUG: peginesatide|DRUG: peginesatide|DRUG: peginesatide|DRUG: peginesatide|DRUG: peginesatide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Potential Effects of Omega 3 Supplementation on Cardiomyocytes Membranes for Patients With Coronary Atherosclerosis?
Status: UNKNOWN
Conditions: Coronary Atherosclerosis
Interventions: DIETARY_SUPPLEMENT: Omega 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Saypha® VOLUME Lidocaine for Midface Augmentation
Status: ACTIVE_NOT_RECRUITING
Conditions: Moderate to Severe Midface Volume Deficit
Interventions: COMBINATION_PRODUCT: saypha® VOLUME Lidocaine|COMBINATION_PRODUCT: Juvéderm® Voluma™ XC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Controlled, Clinical Trial of Biofeedback and Anal Injections as First Treatment of Fecal Incontinence
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: PROCEDURE: 1. Anal injection|PROCEDURE: 2. Biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Systemic, Pancoronary and Local Coronary Vulnerability
Status: COMPLETED
Conditions: Coronary Stenosis|Acute Coronary Syndrome|Acute Myocardial Infarction|Atheromatous Plaques|Atheroscleroses, Coronary|Non-ST Elevation Myocardial Infarction (nSTEMI)
Interventions: DIAGNOSTIC_TEST: Cardiac imaging tests|DIAGNOSTIC_TEST: Venous blood sample collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cardiovascular Effects of GLP-1 Receptor Activation
Status: COMPLETED
Conditions: Obesity|PreDiabetes
Interventions: DRUG: Liraglutide|DRUG: Sitagliptin|OTHER: hypocaloric diet|DRUG: Placebos|DRUG: Exendin (9-39)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Olaparib and Durvalumab With Carboplatin, Etoposide, and/or Radiation Therapy for the Treatment of Extensive-Stage Small Cell Lung Cancer, PRIO Trial
Status: RECRUITING
Conditions: Extensive Stage Lung Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: DRUG: Carboplatin|BIOLOGICAL: Durvalumab|DRUG: Etoposide|DRUG: Olaparib|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Control Trial Testing Connective Tissue Grafts vs. Allograft on Dental Implants
Status: COMPLETED
Conditions: Dental Implant Soft Tissue Defects in the Anterior Maxilla
Interventions: PROCEDURE: Soft Tissue Grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Observation of the Performance of Artis Dialysis System, ArtiSet PrePost and Ultra HDF Line in Treatments of Patients With End-Stage Renal Disease (ESRD)
Status: COMPLETED
Conditions: End-Stage Renal Disease
Interventions: DEVICE: Artis Dialysis System, ArtiSet PrePost and Ultra HDF Line|DEVICE: AK200 Ultra S, extracorporeal circulation conduct of blood purification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Morning-only Bowel Preparation for Afternoon Colonoscopy.
Status: COMPLETED
Conditions: Colon Cancer
Interventions: DRUG: Polyethylene Glycol afternoon|DRUG: Polyethylene Glycol morning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Long-Term Safety and Efficacy of ABT-335, in Combination With Three Different Statins in Subjects With Mixed Dyslipidemia.
Status: COMPLETED
Conditions: Dyslipidemia|Coronary Heart Disease|Mixed Dyslipidemia
Interventions: DRUG: ABT-335 and rosuvastatin calcium|DRUG: ABT-335 and atorvastatin calcium|DRUG: ABT-335 and simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Safety and Efficacy of Platelet Rich Plasma Injection for Atrophic Rhinitis
Status: COMPLETED
Conditions: Atrophic Rhinitis
Interventions: DEVICE: Plasma rich platelet injection|DEVICE: Saline nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin Using as a Possible Prophylaxis of Postoperative Atrial Fibrillation After Cardiac Surgery
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Cardiac surgery|PROCEDURE: Cardiac surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Melatonin for Sleep in Children With Autism
Status: COMPLETED
Conditions: Autistic Disorder|Insomnia
Interventions: DRUG: supplemental liquid melatonin|DRUG: flavored liquid or liquid supplemental melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Avastin Versus Intravitreal Avastin and Triamcinolone in Central Retinal Vein Occlusion(CRVO)
Status: UNKNOWN
Conditions: Retinovascular Disease
Interventions: DRUG: Avastin (Bevacizumab) and triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone and Oxygen Support Strategies in ICU Patients With Covid-19 Pneumonia
Status: UNKNOWN
Conditions: Acute Hypoxemic Respiratory Failure|COVID-19
Interventions: DRUG: Dexamethasone injection|DRUG: placebo|PROCEDURE: conventional oxygen|PROCEDURE: CPAP|PROCEDURE: HFNO|PROCEDURE: mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Participants With Major Depressive Disorder (MDD) With Anhedonia and Inadequate Response to Current Antidepressant Therapy Including a Selective Serotonin Reuptake Inhibitor (SSRI) or Serotonin Norepinephrine Reuptake Inhibitor (SNRI)
Status: RECRUITING
Conditions: Depressive Disorder, Major
Interventions: OTHER: No Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Safety/Efficacy of AmBisome Loading Dose Regimen Versus Standard AmBisome Regimen for Initial Treatment
Status: COMPLETED
Conditions: Invasive Aspergillosis|Other Fungal Infections
Interventions: DRUG: AmBisome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pharmacologic Study of Oseltamivir in Healthy Volunteers
Status: COMPLETED
Conditions: Avian Influenza A Virus
Interventions: DRUG: oseltamivir|DRUG: probenecid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Skin Safety Study to Evaluate the Sensitizing Potential in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: M518101|DRUG: M518101 Vehicle|OTHER: Sodium lauryl sulfate|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Comparison of Three Treatments for Pneumocystis Pneumonia in AIDS Patients
Status: TERMINATED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Trimetrexate glucuronate|DRUG: Methylprednisolone|DRUG: Pentamidine isethionate|DRUG: Sulfamethoxazole-Trimethoprim|DRUG: Leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Long-Term Multicenter Evaluation of the E1® Tibial Bearing
Status: UNKNOWN
Conditions: Osteoarthritis of the Knee|Traumatic Arthritis of the Knee
Interventions: PROCEDURE: Total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Avastin (Bevacizumab) and Irinotecan Versus Temozolomide Radiochemistry in Patients With Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: bevacizumab [Avastin]|DRUG: irinotecan|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rubidium-82 Position Emission Computed Tomography (PET) Versus Gated, Rest / Stress Technetium 99-m SPECT
Status: COMPLETED
Conditions: Coronary Artery Disease|Myocardial Ischemia|Heart Disease
Interventions: OTHER: SPECT imaging|OTHER: PET imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Right Atrial Fibrosis in Pulmonary Hypertension
Status: COMPLETED
Conditions: Pulmonary Hypertension|Chronic Thromboembolic Pulmonary Hypertension|Pulmonary Arterial Hypertension
Interventions: DIAGNOSTIC_TEST: cardiac magnetic resonance imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of New Antibiotic Regimen for the Treatment of Uncomplicated Cellulitis in Emergency Department Patients
Status: COMPLETED
Conditions: Cellulitis
Interventions: DRUG: trimethoprim-sulfamethoxazole|DRUG: Cephalexin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Parvovirus H-1 (ParvOryx) in Patients With Progressive Primary or Recurrent Glioblastoma Multiforme.
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: H-1PV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI and Cardio-Pulmonary Exercise Testing in Evaluating Exercise Intolerance in Patients With Stage I-III Breast Cancer After Chemotherapy Treatment
Status: COMPLETED
Conditions: Healthy Subject|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: OTHER: Cardiopulmonary Exercise Testing|DEVICE: Magnetic Resonance Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Selegiline Patch for Treatment of Nicotine Dependence
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: DRUG: Selegiline|OTHER: matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Precision Dosing of Tyrosine Kinase Inhibitors in CML Patients
Status: COMPLETED
Conditions: CML, Chronic Phase|CML (Chronic Myelogenous Leukemia|CML - Philadelphia Chromosome|Chronic Myeloid Leukemia|Chronic Myeloid Leukemia, Chronic Phase
Interventions: DRUG: Bosutinib|DRUG: Dasatinib|DRUG: Imatinib|DRUG: Nilotinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Test-Drive Strategy for the Prescription of Prosthetic Feet for People With Leg Amputations
Status: COMPLETED
Conditions: Amputation
Interventions: DEVICE: Prosthetic Foot Emulator|DEVICE: Commercially available prosthetic feet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Hepatic Arterial Infusion of Gemcitabine-oxaliplatin for Second-line Therapy in Non-metastatic Unresectable Intra-hepatic Cholangiocarcinoma
Status: RECRUITING
Conditions: Cholangiocarcinoma Non-resectable|Non-metastatic
Interventions: DRUG: Gemcitabine-Oxaliplatin Regimen|PROCEDURE: Hepatic intra arterial chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prediction of Relapse in Schizophrenia/Schizoaffective Disorder With Smartphones and On-body Sensors
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DEVICE: schizophrenia/schizoaffective disorder.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Second-Line Chemotherapy Combined With Endostatin for Recurrent/Metastatic HN Epithelial Tumors
Status: UNKNOWN
Conditions: Head and Neck Neoplasms
Interventions: DRUG: second-line chemotherapy|DRUG: Recombinant human endostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Trial of AZD1775 and Gemcitabine (+Radiation) for Unresectable Adenocarcinoma of the Pancreas
Status: COMPLETED
Conditions: Adenocarcinoma of the Pancreas
Interventions: DRUG: MK-1775|DRUG: Gemcitabine|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Study to Investigate Systemic Exposure in Adult and Pediatric Atopic Dermatitis Patients Treated 8.5 Days With Pimecrolimus Cream 1% Under Occlusion
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Pimecrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravascular ULTRAsound-Guided PCI in Patients With ST-Elevation Myocardial Infarction
Status: NOT_YET_RECRUITING
Conditions: STEMI|Intravascular Imaging|IVUS
Interventions: DEVICE: IVUS imaging for primary PCI guidance
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HFIT Versus TENS Study for Chronic Low Back and Knee Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain|Knee Pain Chronic|Back Pain, Low
Interventions: DEVICE: HFIT|DEVICE: TENS|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Dose-Escalation, Positron Emission Tomography Study to Assess the Safety, Pharmacokinetics, Dosimetry and Biodistribution of GEH200521 (18F) Injection Co-Administered With GEH200520 Injection in Healthy Volunteers
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: GEH200520 Injection and GEH200521 (18F) Injection|DIAGNOSTIC_TEST: Static - PET/CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Restylane Defyne Compared to Restylane for Correction of Moderate to Severe Nasolabial Folds
Status: COMPLETED
Conditions: Nasolabial Folds in Chinese Population
Interventions: DEVICE: Restylane Defyne|DEVICE: Restylane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Evaluate the Safety and Efficacy of Ariva® Silver Wintergreen in Reducing Cigarette Craving in Smokers
Status: COMPLETED
Conditions: Tobacco Use Disorder|Smoking
Interventions: OTHER: Ariva® Silver Wintergreen|OTHER: Silver Wintergreen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Scleroderma: Cyclophosphamide or Transplantation
Status: COMPLETED
Conditions: Scleroderma, Systemic|Sclerosis|Autoimmune Disease
Interventions: BIOLOGICAL: mHSCT|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Advanced Diagnostics for Enhanced QUality of Antibiotic Prescription in Respiratory Tract Infections in Emergency Rooms
Status: COMPLETED
Conditions: Community-acquired Acute Lower Respiratory Infection
Interventions: DEVICE: BioFire FilmArray Respiratory Panel 2.1 plus (RP2.1plus)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Implementation of Innovative Food Prescription Programs in Older Adults
Status: NOT_YET_RECRUITING
Conditions: Food Preferences|Food Habits
Interventions: OTHER: Produce Prescription Delivery|OTHER: Healthy Meal Kit Delivery|OTHER: Produce Prescription Mobile Market
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: LymphBridge: Surgical Evaluation for Breast Cancer-Associated Lymphedema (BioBridge)
Status: RECRUITING
Conditions: Lymphedema|Edema
Interventions: DEVICE: BioBridge® Collagen Matrix|PROCEDURE: Vascularized Lymph Node Transfer (VLNT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Femoral Nerve Catheter and Adductor Canal Block With Steroid Adjuvant in Total Knee Replacement (TKR)
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: PROCEDURE: adductor canal block|PROCEDURE: femoral nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Sulfonylurea
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Lixisenatide (AVE0010)|DRUG: Placebo|DEVICE: Pen auto-injector|DRUG: Sulfonylurea|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Autogenic Inhibition and Reciprocal Inhibition in Amateur Football Players With Shin Splints.
Status: RECRUITING
Conditions: Shin Splint
Interventions: OTHER: Heating Therapy|OTHER: Manual Soft tissue Release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Immunogenicity, and Lot-to-Lot Consistency of H5N1 Subunit Influenza Virus Vaccine in Healthy Adult Subjects ≥18 Years of Age
Status: COMPLETED
Conditions: Avian Influenza
Interventions: BIOLOGICAL: aH5N1c|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Fresh RX: NHS 2020
Status: RECRUITING
Conditions: Premature Birth|Birth Weight|Post Partum Depression|Health Care Utilization|Nutrition Deficiency Due to Insufficient Food|Housing Problems|Fetal Complications|Food Deprivation
Interventions: BEHAVIORAL: FreshRx Nourishing Healthy Starts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacogenetics of Cannabinoid Response
Status: COMPLETED
Conditions: COMT Gene Polymorphism
Interventions: DRUG: delta 9 tetrahydrocannabinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Determine Dose, Safety, Tolerability, Drug Levels, and Efficacy of CC-220 Monotherapy, and in Combination With Other Treatments in Participants With Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: CC-220|DRUG: Dexamethasone|DRUG: Daratumumab|DRUG: Bortezomib|DRUG: Carfilzomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Holistic Wellbeing in COPD: Communication About Sexuality (COSY)
Status: RECRUITING
Conditions: Chronic Disease|Lung Diseases, Obstructive|Respiratory Disease
Interventions: OTHER: Communication intervention about sexuality in people with COPD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Valve Performance of the SAPIEN 3 Ultra RESILIA Valve: A Prospective Registry With Central Echocardiography Analysis.
Status: NOT_YET_RECRUITING
Conditions: Aortic Valve Stenosis|Transcatheter Aortic Valve Replacement
Interventions: PROCEDURE: SAPIEN 3 Ultra RESILIA Valve
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vocal Cord Responses During Hyperventilation in Normal Individuals and in Mild and Severe Asthmatics.
Status: RECRUITING
Conditions: Hyperventilation|Larynx|Asthma
Interventions: OTHER: Acute Hyperventilation|OTHER: Chronic hyperventilation|DRUG: Effects of anticholinergic medication
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: International Consortium for Multimodality Phenotyping in Adults With Non-compaction
Status: RECRUITING
Conditions: Non-Compaction Cardiomyopathy
Interventions: DIAGNOSTIC_TEST: Echocardiography|DIAGNOSTIC_TEST: Magnetic resonance imaging (MRI)|DIAGNOSTIC_TEST: Computed tomography (CT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Group Versus Individual Physiotherapy for Urinary Incontinence in Aging Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Urinary Incontinence|Urinary Stress Incontinence
Interventions: BEHAVIORAL: Group physiotherapy|BEHAVIORAL: Individual one-on-one physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Pharmacokinetics of Escalating Doses of DCDT2980S in Patients With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia And DCDT2980S in Combination With Rituximab in Patients With Relapsed or Refractory B-Cell Non Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma, Chronic Lymphocytic Leukemia
Interventions: DRUG: DCDT2980S|DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flavopiridol and Vorinostat in Treating Patients With Relapsed or Refractory Acute Leukemia or Chronic Myelogenous Leukemia or Refractory Anemia
Status: COMPLETED
Conditions: Blastic Phase Chronic Myelogenous Leukemia|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Refractory Anemia With Excess Blasts|Relapsing Chronic Myelogenous Leukemia|Untreated Adult Acute Lymphoblastic Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: alvocidib|DRUG: vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Real-world Firebird 2 Versus Cypher Sirolimus-eluting Stent in Treating Patients With Coronary Artery Disease
Status: WITHDRAWN
Conditions: Coronary Artery Stenosis
Interventions: DEVICE: Firebird 2 SES|DEVICE: Cypher SES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron Isomaltoside Compared With Iron Sucrosein Peritoneal Dialysis Patients
Status: TERMINATED
Conditions: Iron Deficiency Anemia Treatment
Interventions: DRUG: Iron Isomaltoside|DRUG: Iron sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Proton Pump Inhibitor and Mosapride on Acid Pocket in Gastroesophageal Reflux Disease
Status: UNKNOWN
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Administration of study drug (esomeprazole, mosapride)|DRUG: Administration of study drug (esomeprazole, placebo tablet)|PROCEDURE: upper endoscopy, scintigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of the Contribution of Fractional Exhaled Nitric Oxide as a Prognostic Marker of Response to Anti-PD-L1 Immunotherapy in Non-small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Metastatic Non-small Cell Lung Cancer
Interventions: OTHER: Measurement of FeNO
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate SAGE-217 in Participants With Moderate to Severe Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depression
Interventions: DRUG: SAGE-217|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimising Operational Use of Artemether-lumefantrine Comparing 3 Day Versus 5 Day
Status: COMPLETED
Conditions: Plasmodium Falciparum Infection
Interventions: DRUG: Artemether-lumefantrine 3 days|DRUG: Artemether-lumefantrine 5 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health, Fitness, and Quality of Life in Adolescent Girls With Turner Syndrome
Status: COMPLETED
Conditions: Turner Syndrome|Turner Syndrome Mosaicism, 45, X/46, XX or XY|Turner Syndrome Mosaicism 46,X,I(X)(Q10)/45,X|Turner Syndrome Karyotype 46,X With Abnormal Sex Chromosome , Except I(Xq)
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Efficacy and Safety of Agalsidase Beta in Heterozygous Females for Fabry Disease
Status: UNKNOWN
Conditions: Fabry Disease
Interventions: DRUG: recombinant alpha-galactosidase A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bright Start Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: Written Educational Material on BLT|BEHAVIORAL: Enhanced BLT Encouragement and Adherence Promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Esketamine Combined With Remimazolam on Postoperative Sleep Disturbance and Anxiety in Patients
Status: RECRUITING
Conditions: Sleep Disturbance
Interventions: DRUG: Esketamine|DRUG: Remimazolam|DRUG: Esketamine and remimazolam|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Drug Levels of Orally Administered BMS-986368 in Healthy Participants, Healthy Elderly Participants, and Healthy Participants of Japanese Ethnicity
Status: RECRUITING
Conditions: Healthy Participants
Interventions: DRUG: BMS-986368
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Spinal Ketorolac on Mechanical Hypersensitivity After a Total Hip Replacement
Status: TERMINATED
Conditions: Hip Arthroplasty
Interventions: DRUG: ketorolac tromethamine opthalmic solution|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact on Antibiotic Prescriptions of a Bundle Intervention Conducted by Medical Representatives in General Practitioner Facilities, Based on Operational Demonstration of an Internet Decision Support Tool: Antibioclic
Status: COMPLETED
Conditions: Antibiotic Resistance
Interventions: OTHER: Visit to GPs to promote good antibiotic prescription with the help internet tool for decision: ANTIBIOCLIC|OTHER: Visit to GPs to promote good antibiotic prescription without presentation of the internet tool for decision support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: BBR 2778 for Relapsed, Aggressive Non-Hodgkin's Lymphoma (NHL)
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: pixantrone, cyclophosphamide, vincristine, rituximab, prednisone|DRUG: Vinorelbine, Oxalplatin, Ifosfasmide, Etoposide, Mitoxatrone, Gemcitabine or Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Response of Neuropathic And Non-Neuropathic POTS Patients To Adrenoreceptor Agonist And Antagonist
Status: TERMINATED
Conditions: Postural Orthostatic Tachycardia Syndrome|Orthostatic Intolerance
Interventions: DRUG: Droxidopa|DRUG: Atenolol|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Prebiotics on Gut Microbiome in Patients Undergoing HSCT
Status: COMPLETED
Conditions: Multiple Myeloma|Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Non Hodgkin Lymphoma|Acute Lymphocytic Leukemia|Hodgkin Lymphoma|Hodgkin Disease|Myelofibrosis|Myelodysplastic Syndromes|Myeloproliferative Neoplasm|Sickle Cell Disease|Mantle Cell Lymphoma
Interventions: OTHER: Pre-biotic foods/drinks
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Core Stabilization Exercises on Balance and Quality of Life in Chronic Period in Individuals With Lumbar Disc Herniation
Status: COMPLETED
Conditions: Lumbar Disc Herniation|Balance; Distorted
Interventions: OTHER: exercise treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Baclofen for the Treatment of Alcohol Drinkers
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: Baclofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet Inhibition of Ticagrelor Versus Clopidogrel in Type 2 Diabetic Patients After Elective Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Coronary Artery Disease|Diabetes Mellitus, Type 2
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Type I-Polarized Autologous Dendritic Cell Vaccine With Tumor Blood Vessel Antigen-Derived Peptides in Metastatic Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer|Metastatic Breast Cancer
Interventions: BIOLOGICAL: tumor blood vessel antigen peptide-pulsed alpha-type-1 polarized dendritic cell vaccine|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ketorolac Buccal Infiltration on Success Rate of Inferior Alveolar Nerve Block
Status: COMPLETED
Conditions: Failed Mechanical Induction
Interventions: DRUG: Ketorolac Tromethamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of MEDI9929 (AMG 157) in Adult Subjects With Inadequately Controlled, Severe Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Placebo|DRUG: MEDI9929 70 mg|DRUG: MEDI9929 210 mg|DRUG: MEDI9929 280 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Various Combinations of Avelumab as Therapy in Locally Advanced or Metastatic Urothelial Carcinoma (JAVELIN Bladder Medley)
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced or Metastatic Urothelial Carcinoma
Interventions: DRUG: Avelumab|DRUG: Sacituzumab Govitecan|DRUG: M6223|DRUG: NKTR-255
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Effect of Strengthening Referral of Sick Children From the Private Health Sector and Its Impact on Referral Uptake in Uganda.
Status: UNKNOWN
Conditions: Malaria
Interventions: BEHAVIORAL: Strenghtened referral of children
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Gaze Stabilization Exercises on Dizziness, Balance and Quality of Life in Cervical Spondylosis Patients
Status: COMPLETED
Conditions: Dizziness|Balance; Distorted|Cervical Spondylosis
Interventions: OTHER: gaze stabilization exercises|OTHER: neck isometrics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RT001 in Patients With Progressive Supranuclear Palsy (PSP) PROGRESSIVE SUPRANUCLEAR PALSY
Status: UNKNOWN
Conditions: Progressive Supranuclear Palsy
Interventions: DRUG: RT001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy and Combination Chemotherapy in Treating Patients With Stage II or Stage III Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: cisplatin|DRUG: gemcitabine hydrochloride|DRUG: paclitaxel|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of QL0911 in Adult Patients With Chronic Primary Immune Thrombocytopenia
Status: COMPLETED
Conditions: Primary Immune Thrombocytopenia
Interventions: DRUG: QL0911|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Investigate Palbociclib (PD-0332991) Pharmacokinetics In Healthy Subjects Of Japanese Descent Relative To Healthy Non-Asian Subjects, And To Determine If Changes In Palbociclib Dose Result In Proportional Changes In Palbociclib Plasma Exposure In Japanese Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Palbociclib 75mg|DRUG: Palbociclib 125mg|DRUG: Palbociclib 100mg|DRUG: Palbociclib|DRUG: Palbociclib 125mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized Trial of DOTS Versus Enhanced DOTS for Community Control of Tuberculosis
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: Isoniazid|DRUG: Pyrazinamide|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: WellPATH-PREVENT: A Mobile Intervention for Middle-Aged and Older Adults Hospitalized for Suicidal Ideation or Attempt
Status: RECRUITING
Conditions: Suicide, Attempted|Suicidal Ideation|Depression
Interventions: BEHAVIORAL: WellPATH-PREVENT|BEHAVIORAL: Optimized WellPATH-PREVENT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Open Label Placebo to Reduce Prescription Opioid Use
Status: RECRUITING
Conditions: Acute Pain
Interventions: DIETARY_SUPPLEMENT: Open Placebo|OTHER: Opioid medication as part of standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effect of Therapeutic Massage on Sleep Quality and Stress Levels in Women With Breast Cancer
Status: COMPLETED
Conditions: Sleep Disturbance|Anxiety
Interventions: OTHER: Therapeutic massage|OTHER: Sham massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Automated MEdical Record Driven Implantable CArdioverter-defibrillator Heart Failure Trial (AMERICA-HF)
Status: TERMINATED
Conditions: Heart Failure
Interventions: OTHER: Automated HF/EP Referral|OTHER: Placebo (Registry Arm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Naldemedine (S-297995) for the Treatment of Opioid-Induced Bowel Dysfunction in Subjects With Chronic Pain
Status: COMPLETED
Conditions: Opioid Induced Bowel Dysfunction
Interventions: DRUG: Naldemedine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tuberculosis and Human Immunodeficiency Virus (HIV) Immune Reconstitution Syndrome Trial (THIRST)
Status: COMPLETED
Conditions: HIV|Tuberculosis
Interventions: DRUG: Fixed dose combination zidovudine/lamivudine/abacavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ivermectin and Doxycycline in Combination or IVE Alone in Patients With COVID-19 Infection.
Status: COMPLETED
Conditions: COVID-19 Patients
Interventions: DRUG: Ivermectin + Doxycycline + Placebo|DRUG: Ivermectin + Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Bioequivalence Study of Acyclovir 800 mg Tablet in Healthy Thai Volunteers Under Fasting Conditions
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteer
Interventions: DRUG: Acyclovir 800 mg Tablet|DRUG: Zovirax™ 800 mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Pilates in Patients With Post- -COVID-19 Syndrome: Controlled and Randomized Clinical Trial
Status: RECRUITING
Conditions: COVID-19
Interventions: PROCEDURE: Pilates Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Biofeedback Treatment in Constipated Patients With Idiopathic Parkinson's Disease
Status: COMPLETED
Conditions: Idiopathic Parkinson's Disease|Constipation
Interventions: OTHER: biofeedback therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nab-Sirolimus and Pazopanib Hydrochloride in Treating Patients With Advanced Nonadipocytic Soft Tissue Sarcomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Soft Tissue Sarcoma|Locally Advanced Soft Tissue Sarcoma|Metastatic Soft Tissue Sarcoma
Interventions: DRUG: Sirolimus Albumin-bound Nanoparticles|DRUG: Pazopanib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Poly-unsaturated Fatty Acids and Developmental Dyslexia
Status: RECRUITING
Conditions: Dyslexia, Developmental
Interventions: DIETARY_SUPPLEMENT: Poly-unsaturated fatty acids supplementation|BEHAVIORAL: Neuropsychological intervention|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Coagulation in Acute Aortic Dissection
Status: RECRUITING
Conditions: Acute Aortic Dissection|Coagulation Disorder
Interventions: PROCEDURE: Individualized HDR-approach|PROCEDURE: Conventional ACT-approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Estimation of the Result of the MitraClip Technique: Interest of the Ratio of Mean Arterial Pressure (MAP) to Pressure of the Mean Left Atrium (POG) (MitraPOG)
Status: UNKNOWN
Conditions: Mitral Insufficiency|Mitraclip
Interventions: PROCEDURE: Monitoring of the pressure of the middle left atrium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Zolpidem on CPAP Acclimatization in OSA
Status: NOT_YET_RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Zolpidem|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of EPOCH II Versus EPOCH II and Immunotherapy in Lymphomas
Status: COMPLETED
Conditions: Hodgkin's Disease|Non Hodgkin's Lymphoma
Interventions: PROCEDURE: PBSC|DRUG: IL-2|DRUG: EPOCH II
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Huperzine-A to Help With Mental Problems and the Inability to Care for Onself in Patients With Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia|Dementia
Interventions: DRUG: Huperzine A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritional Intervention IN Nash NON-ALCOHOLIC (NAFLD).
Status: ACTIVE_NOT_RECRUITING
Conditions: Steatohepatitis, Nonalcoholic|Steatosis|Liver Diseases|Steatohepatitis
Interventions: BEHAVIORAL: NUTRITIONAL EDUCATIONAL INTERVENTION IN FATTY LIVER DISEASE NON-ALCOHOLIC (NAFLD).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Henagliflozin on Cardiac Function in Type 2 Diabetes Patients With Chronic Heart Failure (HERO-HF)
Status: RECRUITING
Conditions: Heart Failure
Interventions: DRUG: Henagliflozin 10 mg|DRUG: blank control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study on Adjuvant Chemotherapy and Adjuvant Chemo-Immunotherapy in Colon Carcinoma Dukes C
Status: COMPLETED
Conditions: Colon Cancer Stage III
Interventions: DRUG: 5-fluorouracil, levamisol, interferon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Speed-based Training on Spasticity and Balance
Status: UNKNOWN
Conditions: Stroke|Spasticity, Muscle|Balance; Distorted
Interventions: OTHER: Speed-based relearning training|OTHER: Neurodevelopmental Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clairleafᵀᴹ: A Study to Test Long-term Treatment With BI 1291583 in People With Bronchiectasis Who Took Part in a Previous Study With This Medicine
Status: RECRUITING
Conditions: Bronchiectasis
Interventions: DRUG: BI 1291583|DRUG: Placebo matching BI 1291583
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT