pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Decrease Artery Occlusion by Distal Radial Arterial Cannulation in ACS Patients
Status: UNKNOWN
Conditions: Acute Coronary Syndrome|Procedural Complication
Interventions: PROCEDURE: distal TRA group|PROCEDURE: conventional TRA group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of CNDO 201Trichuris Suis Ova (TSO) for the Treatment of Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: TSO 2500|DRUG: TSO 7500
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ototoxicity of Artemether / Lumefantrine (Coartem) and Other Antimalarials
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: artemether/lumefantrine|DRUG: quinine|DRUG: atovaquone/proguanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Dynamic Full-field Optical Coherence Tomography for Structural and Microbiological Characterization of Endotracheal Tube Biofilm in Critically Ill Patients
Status: RECRUITING
Conditions: Healthcare Associated Infection|Critically Ill|Endotracheal Tube
Interventions: OTHER: •Dynamic Full-Field Optical Coherence Tomography analysis of endotracheal tube
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Contrast Enhanced Voiding Urosonography for Urodynamic Studies
Status: UNKNOWN
Conditions: Myelomeningocele|Neurogenic Bladder|Tethered Cord Syndrome|Bladder, Neurogenic|Urologic Diseases|Neurologic Dysfunction
Interventions: DRUG: Contrast Enhanced Voiding Urosonography with Urodynamic Testing|DIAGNOSTIC_TEST: Urodynamic Testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preventing T2DM After GDM With Immediate Postpartum Screening and Treatment
Status: NOT_YET_RECRUITING
Conditions: Gestational Diabetes|Type 2 Diabetes
Interventions: DRUG: Metformin Hydrochloride|OTHER: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spinal Anesthetic for Hip and Knee Replacement Surgery - Intrathecal Morphine or Hydromorphone
Status: WITHDRAWN
Conditions: Spinal Anesthesia
Interventions: PROCEDURE: spinal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Efficacy and Security of Darunavir/Ritonavir 900/100 mg Once a Day as an Antiretroviral Treatment Simplification Strategy
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Darunavir 900mg + ritonavir 100 mg once a day|DRUG: Darunavir 600mg + ritonavir 100mg twice day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tamoxifen in Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Tamoxifen|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumors: A Pilot Feasibility Study
Status: RECRUITING
Conditions: Pediatric Brain Tumor
Interventions: BEHAVIORAL: HIIT Exercise Program|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Medico-economic Interest of Single-use Ancillary Efficiency® in Fitting a GMK® Total Knee Arthroplasty (TKA)
Status: UNKNOWN
Conditions: Knee Arthropathy
Interventions: DEVICE: knee total arthroplasty with two types of ancillaries
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Immediate Effect of Mindfulness-Based Supportive Therapy on Palliating Suffering in Palliative Care Cancer Patients
Status: COMPLETED
Conditions: Cancer|Suffering
Interventions: OTHER: 30-minute Mindfulness-Based Supportive Therapy|OTHER: 30-minute supportive listening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial of a Group Self-management Support Program for Anxiety Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Panic Disorder|Agoraphobia|Social Anxiety Disorder|Generalized Anxiety Disorder
Interventions: BEHAVIORAL: Group self-management support program for anxiety disorders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Mandibular Exercises Effect on Pain Perception and Sensitivity in Mandibular Myofascial Pain
Status: COMPLETED
Conditions: Temporomandibular Disorders
Interventions: OTHER: Isometric mandibular exercises|OTHER: Isotonic mandibular exercises|BEHAVIORAL: Counseling group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Dexmedetomidine for Deep Sedation in Patients Undergoing Outpatient Hysteroscopic Surgery
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Placebo Comparator|DRUG: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bepotastine Besilate Nasal Sprays in the Treatment of Seasonal Allergic Rhinitis (SAR)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Bepotastine besilate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Investigate the Incidence of Reflux in Patients After Per-oral Endoscopic Myotomy in Achalasia Cardia Patients
Status: COMPLETED
Conditions: Achalasia Cardia|Gastroesophageal Reflux
Interventions: PROCEDURE: Peroral endoscopic myotomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: "Living Low - Training High" Methods and Physiological Responses in Well-trained Swimmers
Status: NOT_YET_RECRUITING
Conditions: Normobaric Hypoxia|Hypoventilation|Normoxia
Interventions: OTHER: Repeated sprint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Plasmonic Nanophotothermal Therapy of Atherosclerosis
Status: COMPLETED
Conditions: Stable Angina|Heart Failure|Atherosclerosis|Multivessel Coronary Artery Disease
Interventions: PROCEDURE: Transplantation of nanoparticles|PROCEDURE: Transplantation of iron-bearing nanoparticles|DEVICE: Stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Flaxseed as Maintenance Therapy for Ovarian Cancer Patients in Remission
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: DRUG: Omega Nutrition cold-milled flaxseeds
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hemoadsorption With CytoSorb® in Post-Cardiac Arrest Syndrome
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: DEVICE: CytoSorb® Hemoadsorption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adaptive Implementation to Optimize Delivery of Obesity Prevention Practices in Early Care and Education Settings
Status: RECRUITING
Conditions: Obesity, Childhood|Nutrition Aspect of Cancer
Interventions: BEHAVIORAL: Low Intensity|BEHAVIORAL: High Intensity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial Comparing Approaches to Shared Decision Making Skills Training for Clinicians
Status: COMPLETED
Conditions: Depression|Low Back Pain
Interventions: BEHAVIORAL: Webinar|BEHAVIORAL: DA viewing|BEHAVIORAL: SPI feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Outcome of Crisis Intervention for Subjects With Borderline Personality Disorder or Post-Traumatic Stress Disorder
Status: UNKNOWN
Conditions: Borderline Personality Disorder|Post-Traumatic Stress Disorders
Interventions: BEHAVIORAL: Crisis resolution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of People With Generalized Arterial Calcification of Infancy (GACI) or Autosomal Recessive Hypophosphatemic Rickets Type 2 (ARHR2)
Status: COMPLETED
Conditions: Generalized Arterial Calcification of Infancy|Autosomal Recessive Hypophosphatemic Rickets Type2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low and High Doses of Prophylactic Vitamin D in Prevention of Osteopenia of Prematurity
Status: COMPLETED
Conditions: Osteopenia of Prematurity
Interventions: DRUG: Low Dose Vitamin D|DRUG: High Dose Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Everolimus in Castrated Resistant Prostate Cancer(CRPC)Patients With PI3K-AKT-mTOR Signaling Pathway Deficiency
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: Everolimus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Restructuring in Managing Breakup Distress and Promoting Posttraumatic Growth Among Malaysian Young Adults
Status: NOT_YET_RECRUITING
Conditions: Breakup Distress|Posttraumatic Growth
Interventions: BEHAVIORAL: Cognitive restructuring|BEHAVIORAL: Supportive counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Goat Milk Infant Formula Comfort Study
Status: COMPLETED
Conditions: Gastrointestinal Diseases|Cow's Milk Intolerance
Interventions: DIETARY_SUPPLEMENT: Goat milk-based infant formula|DIETARY_SUPPLEMENT: Cow's milk-based infant formula with probiotic drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Acceptability of Collaborative Care for People With Musculoskeletal and Mental Problems
Status: RECRUITING
Conditions: Mental Disorder|Musculoskeletal Diseases
Interventions: OTHER: Collaborarive Care Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Aprepitant (MK-0869) in Pediatric Participants Undergoing Surgery (MK-0869-148)
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Aprepitant|DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of DITROPAN XL (Oxybutynin Chloride) Versus DETROL LA (Tolterodine Tartrate) in Treatment of Overactive Bladder
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DRUG: oxybutynin chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Reducing Anxiety of Children and Their Parents in the Pre-elective Surgery Process
Status: COMPLETED
Conditions: Preoperative Care|Child|Parent|Anxiety
Interventions: OTHER: Distract with play dough|OTHER: Distract with play kaleidoscope|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A FOUR SESSION ONLINE OCCUPATIONAL THERAPY GROUP TRANINIG FOR MOTHERS OF CHILDREN WITH FEEDING PROBLEMS
Status: COMPLETED
Conditions: Feeding and Eating Disorders|Child Behavior Problem|Feeding Behavior|Online Intervention|Occupational Therapy
Interventions: OTHER: Online Occupational Therapy Group Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dental Implant Approach for Crestal Sinus Elevation; A Novel Technique.
Status: COMPLETED
Conditions: Maxillary Sinus|Dental Implant|Maxillary Sinus Lift|Maxillary Sinus Elevation
Interventions: PROCEDURE: Dental Implant Approach for Crestal Sinus Elevation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Left Ventricular Ejection Fraction in Cardiac Arrest Survivors Treated With Extracorporeal Cardiopulmonary Resuscitation
Status: COMPLETED
Conditions: Out-of-Hospital Cardiac Arrest|Extracorporeal Cardiopulmonary Resuscitation
Interventions: OTHER: Collection of data from the patient's medical file
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: L-arginine and Vitamin D Adjunctive Therapy in Pulmonary Tuberculosis (TB)
Status: COMPLETED
Conditions: Smear Positive Pulmonary Tuberculosis
Interventions: DRUG: L-arginine|DRUG: Vitamin D|DRUG: Placebo L-arginine|DRUG: Placebo Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Oral NXC-736 in Adult Participants With Severe Alopecia Areata
Status: NOT_YET_RECRUITING
Conditions: Alopecia Areata
Interventions: DRUG: NXC736|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Slow-release Locally Administered 0.02% Hypochlorite Formulation
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: COMBINATION_PRODUCT: PerioTabs® brushing solution|COMBINATION_PRODUCT: Chlorhexidine 0.12 %
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cirmtuzumab Consolidation for Treatment of Patients With Detectable CLL on Venetoclax
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Cirmtuzumab|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proximal Molecular Effects of Concurrent Chemoradiotherapy on Head and Neck Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: BIOLOGICAL: the arachidonic acid and EGFR signaling pathways and their interaction in HNSCC tumorigenesis,
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of ISIS 678354 (AKCEA-APOCIII-LRx) in Participants With Hypertriglyceridemia and Established Cardiovascular Disease (CVD)
Status: COMPLETED
Conditions: Hypertriglyceridemia|Cardiovascular Diseases
Interventions: DRUG: ISIS 678354|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of SYHX1901 Tablet in Non-segmental Vitiligo Patients
Status: RECRUITING
Conditions: Non-segmental Vitiligo
Interventions: DRUG: SYHX1901|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Salivary Alpha Amylase as a Biomarker of Transdermal Vagus Nerve Stimulation
Status: COMPLETED
Conditions: No Condition Salivary Alpha Amylase
Interventions: OTHER: Transdermal Vagus Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vardenafil as add-on Therapy for Patients With Pulmonary Hypertension Treated With Inhaled Iloprost
Status: UNKNOWN
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Levitra
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Effects Using Light-Emitting Diode Therapy (LEDT) During a Resistance Exercise Protocol for Asthmatic Patients
Status: COMPLETED
Conditions: Resistance Training
Interventions: DEVICE: Light-Emitting Diode Therapy (LEDT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Treatment of Migraine With e-TNS
Status: COMPLETED
Conditions: Migraine
Interventions: DEVICE: CEFALY Active|DEVICE: CEFALY Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Eradication of Residual Disease by Preemptive Immunointervention After Allogeneic Hematopoietic Stem Cells Transplantation in Chronic Lymphocytic Leukemia
Status: UNKNOWN
Conditions: Chronic Lymphocytic Leukemia|Lymphocytic Lymphoma
Interventions: DRUG: Fludarabin (post-allograft immunosuppressive therapy modulation and DLI Mononuclear cells from allogenic blood)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sunitinib Malate in Treating Patients With Locally Recurrent, Locally Advanced, Unresectable, or Metastatic Urinary Tract Cancer
Status: UNKNOWN
Conditions: Bladder Cancer|Transitional Cell Cancer of the Renal Pelvis and Ureter|Urethral Cancer
Interventions: DRUG: sunitinib malate|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of Sunitinib In Combination With Docetaxel Vs Docetaxel In Patients With Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Sunitinib malate|DRUG: Taxotere
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Microneedling on Coverage of RT1 Gingival Recession in Thin Phenotype.
Status: NOT_YET_RECRUITING
Conditions: Gingival Recession, Localized
Interventions: PROCEDURE: microneedling followed by CAF procedures|PROCEDURE: CAF procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study to Evaluate the Efficacy and Safety of GC6101A in Subjects With Gastritis
Status: UNKNOWN
Conditions: Gastritis
Interventions: DRUG: GC6101A 37.5mg|DRUG: GC6101A 75mg|DRUG: GC6101A 150mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab (Avastin) and RAD001(Everolimus)in the Treatment of Advanced Clear Cell Renal Carcinoma
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: DRUG: bevacizumab|DRUG: RAD001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Timeliness of DTaP-IPV-Hib Vaccination Affect Development of Atopic Dermatitis Before 1 Year of Age?
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: RQ1a: Delayed vs. timely vaccination with the 1st dose of DTaP-IPV-Hib|BIOLOGICAL: RQ1b: Delayed vs. timely vaccination with the 2nd dose of DTaP-IPV-Hib|BIOLOGICAL: RQ2: Vaccination with DTaP-IPV-Hib compared to being unvaccinated
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cost Comparison of Cardiac Magnetic Resonance Imaging (MRI) Use in Emergency Department (ED) Patients With Chest Pain
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Chest Pain
Interventions: OTHER: Observation unit care, coupled with cardiac MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Cortisone Injection vs Trigger Point Dry Needling Fin the Treatment of Greater Trochanter Pain Syndrome: A Pilot Study
Status: COMPLETED
Conditions: Hip Injuries
Interventions: DRUG: Cortisone Injection|PROCEDURE: Trigger Point Dry Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dexmedetomidine and Dopamine on Renal Function After Major Surgery
Status: UNKNOWN
Conditions: Renal Function
Interventions: DRUG: Dexmedetomidine|DRUG: Dopamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating Efficacy and Safety of Gepotidacin Compared With Ceftriaxone Plus Azithromycin in the Treatment of Uncomplicated Urogenital Gonorrhea
Status: COMPLETED
Conditions: Gonorrhea
Interventions: DRUG: Gepotidacin|DRUG: Ceftriaxone|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study to Rule Out Myocardial Infarction by Cardiac Computed Tomography
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Myocardial Infarction|Unstable Angina Pectoris
Interventions: RADIATION: Cardiac Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: S0309, Repository: Blood/Bone Marrow From Pts. With Myeloma, WM, Amyloidosis, or MGUS.
Status: COMPLETED
Conditions: Multiple Myeloma|Smoldering Myeloma|Waldenstrom's Macroglobulinemia|Monoclonal Gammopathy of Undetermined Significance|Amyloidosis
Interventions: OTHER: biologic sample preservation procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adjuvant Cisplatin Plus Gemcitabine in Operable Cholangiocellular Carcinoma.
Status: COMPLETED
Conditions: Cholangiocellular Carcinoma
Interventions: DRUG: Cisplatin and Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Classification of the Sagittal Profile of the Spine in Asymptomatic Elderly Subjects
Status: UNKNOWN
Conditions: Aged|Asymptomatic Condition
Interventions: RADIATION: X-ray examination|OTHER: fall-risk assessment|OTHER: gait cycle analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study of Safety, Tolerability, and Pharmacokinetics of REGN2477 Alone and in Combination With REGN1033 in Healthy Postmenopausal Women and Healthy Adult Men
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: REGN1033|DRUG: REGN2477|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Napping, Sleep, Cognitive Decline and Risk of Alzheimer's Disease
Status: RECRUITING
Conditions: Sleep|Alzheimer Disease|Cognitive Impairment|Aging|CBT
Interventions: BEHAVIORAL: Sleep intervention|BEHAVIORAL: Placebo intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study Comparing GB241 And Rituximab in Patients With B-cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: B-Cell Lymphoma
Interventions: BIOLOGICAL: GB241|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Intensity Conditioning and Haploidentical Related Bone Marrow for Patients With Hematologic Diseases
Status: TERMINATED
Conditions: Acute Leukemias|Burkitt's Lymphoma|Chronic Myelogenous Leukemia
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|RADIATION: Total Body Irradiation|BIOLOGICAL: Haploidentical stem cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Propofol and Fentanyl Versus Midazolam and Fentanyl for Endoscopy Sedation in Cirrhotic Patients
Status: UNKNOWN
Conditions: Cirrhosis
Interventions: DRUG: Propofol|DRUG: Midazolam|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Initiation of Resuscitation While Attached to the Cord With Congenital Diaphragmatic Hernia
Status: WITHDRAWN
Conditions: Congenital Diaphragmatic Hernia
Interventions: PROCEDURE: Ventilatory support while attached to the cord|PROCEDURE: Immediate cord clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Non Bacterial Prostatitis: a Trial of TRUS Guided Injection of Betamethason
Status: UNKNOWN
Conditions: Chronic Non Bacterial Prostatitis
Interventions: DRUG: Betamethason Sodium Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Isthmic Spondylolisthesis Treated With Combined Approach: Clinical and Radiological Outcomes
Status: COMPLETED
Conditions: Isthmic Spondylolisthesis|Surgical Procedure, Unspecified
Interventions: PROCEDURE: Observational study evaluating the results of an intervention for isthmic spondylolisthesis: surgical procedure with double approach: Anterior lumbar Interbody Fusion then postero-lateral fusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Efficacy and Safety of Leronlimab for Patients With Severe or Critical Coronavirus Disease 2019 (COVID-19)
Status: UNKNOWN
Conditions: Coronavirus Disease 2019
Interventions: DRUG: Placebos|DRUG: Leronlimab (700mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Theory-Driven Manualized Approach to Improving New Learning and Memory in Healthy Aging and MCI
Status: NOT_YET_RECRUITING
Conditions: Aging
Interventions: BEHAVIORAL: STEM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Combined Biofeedback-virtual Reality System for Reduction of Fear of Hypoglycemia
Status: UNKNOWN
Conditions: Hypoglycemia|Type One Diabetes
Interventions: BEHAVIORAL: Psych-Educational session and virtual reality|BEHAVIORAL: Psych-Educational and BF sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Adductor Magnus Tenodesis in Patients With Recurrent Patellar Dislocation.
Status: COMPLETED
Conditions: Recurrent Patellar Dislocation|Patellar Instability|Patellofemoral Osteoarthritis
Interventions: PROCEDURE: Adductor magnus tenodesis for recurrent patellar dislocation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison of Quality of Life Between MAlone Procedure and Percutaneaous Endoscopic Caecostomy in Patients With Antegrade Colonic Enema
Status: COMPLETED
Conditions: Constipation Aggravated|Fecal Incontinence With Fecal Urgency
Interventions: PROCEDURE: Malone Procedure|PROCEDURE: Percutaneous endoscopic caecostomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tomivosertib in Relapsed or Refractory Acute Myeloid Leukemia (AML)
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Tomivosertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Pharmacokinetics Study of IDP-118 Lotion in Pediatric Participants With Plaque Psoriasis
Status: RECRUITING
Conditions: Psoriasis
Interventions: DRUG: IDP-118 Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Therapy and Therapeutic Exercise for Chemotherapy Induced Peripheral Neuropathy (CIPN)
Status: COMPLETED
Conditions: Colon Neoplasms|Colorectal Neoplasms
Interventions: BEHAVIORAL: Standard Care|OTHER: Ultrasound Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Modeling and Closed-loop Control of Depth of Anaesthesia
Status: RECRUITING
Conditions: The Focus is to Develop a Closed-loop Control System for Anaesthesia in Vitroretinal Surgery, Surgery Due to Expansive Processes in Head, and Long-term Sedation
Interventions: DRUG: Propofol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: One-year Mortality After Surgery and Low Bispectral Index
Status: COMPLETED
Conditions: General Anesthesia
Interventions: DEVICE: manual administration of iv anesthetics (propofol and remifentanil) using the Toolbox platform|DEVICE: closed-loop administration of iv anesthetics (propofol and remifentanil) using the Toolbox platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Versus Ketamine Versus Magnesium Sulfate for the Prevention of Emergence Agitation Following Sevoflurane Induced Anesthesia in Cardiac Catheterization in Pediatrics
Status: RECRUITING
Conditions: Anesthesia Emergence Delirium
Interventions: DRUG: Dexmedetomidine|DRUG: Ketamine|DRUG: Magnesium|OTHER: normal saline 0.9% NaCL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: I-FIGS Feasibility Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Liver Cancer|Hepatocellular Carcinoma|Liver Metastasis Colon Cancer
Interventions: PROCEDURE: Standard Liver Surgery|DIAGNOSTIC_TEST: Indocyanine Fluorescent Image Guided Surgery (I-FIGS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine for Preventing Depression in Patients Undergoing Treatment for Pancreatic or Head and Neck Cancers
Status: WITHDRAWN
Conditions: Head and Neck Cancer|Pancreatic Cancer|Depression
Interventions: DRUG: Ketamine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention of Parastomal Hernias With a Preformed Three-dimensional, Funnel-shaped Mesh
Status: NOT_YET_RECRUITING
Conditions: Parastomal Hernia
Interventions: PROCEDURE: Permanent colostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Primary CNS Lymphoma ( FTD )
Status: COMPLETED
Conditions: Primary CNS Lymphoma (PCNSL)
Interventions: DRUG: HD-MTX-Ara-C regimen|DRUG: FTD regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Allogeneic Mesenchymal Stem Cells in Patients With Rapidly Progressive Interstitial Lung Disease
Status: COMPLETED
Conditions: Idiopathic Interstitial Pneumonia|Interstitial Lung Disease|Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Bone marrow mesenchymal stem cells|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Tissucol/Tisseel Fibrin Sealant to Treat Inguinal Hernia
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: PROCEDURE: standardized Lichtenstein technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Walking Analysis After a Total Knee Arthroplasty With Kinematic Alignment Versus Mechanical Alignment
Status: RECRUITING
Conditions: Knee Arthroplasty, Total
Interventions: PROCEDURE: total knee arthroplasty with a kinetic alignment|PROCEDURE: total knee arthroplasty with a mechanical alignment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Cost-Effectiveness of a Tele-Rehabilitation Program in the Treatment of Chronic Musculoskeletal Pain
Status: UNKNOWN
Conditions: Chronic Pain
Interventions: OTHER: Internet-Based Pain Education and Exercise|OTHER: Online Booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Natural Cycle vs Programmed Cycle Frozen Embryo Transfer
Status: RECRUITING
Conditions: Infertility|Frozen Embryo Transfer|Preeclampsia and Eclampsia
Interventions: PROCEDURE: Natural Cycle|PROCEDURE: Artificial Cycle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Therapies Before Stem Cell Transplantation in Patients With Higher Risk MDS and Oligoblastic AML
Status: RECRUITING
Conditions: MDS|AML
Interventions: DRUG: CPX-351|DRUG: Daunorubicin|DRUG: Cytarabine|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: V710 Clinical Study in Healthy Male Japanese Subjects (V710-006) (COMPLETED)
Status: COMPLETED
Conditions: Staphylococcal Infection
Interventions: BIOLOGICAL: V710|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pain Neuroscience Education in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Pain, Chronic|Fibromyalgia
Interventions: OTHER: Pain neuroscience education|DRUG: Medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effectiveness of Different Conservative Treatment Protocols in Postprostatectomy Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence|Prostate Cancer|Urinary Incontinence,Stress|Urinary Incontinence Due to Urethral Sphincter Incompetence
Interventions: OTHER: First research arm|OTHER: Second research arm|OTHER: Third research arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Neurofeedback Training for Older Adults With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment, So Stated
Interventions: BEHAVIORAL: SMR neurofeedback training to MCI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pathogenesis of Acute Stress Induced (Tako-tsubo) Cardiomyopathy: Energy Shut-Down or Intense Inflammation?
Status: COMPLETED
Conditions: Tako-tsubo Cardiomyopathy
Interventions: PROCEDURE: Magnetic resonance imaging|BIOLOGICAL: Acute Inflammatory Activation study|RADIATION: PET CT|BEHAVIORAL: Psychological assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of the Lentiviral Vector in Gene Therapy of Beta-thalassemia Patients
Status: RECRUITING
Conditions: Transfusion-dependent Beta-Thalassemia
Interventions: GENETIC: KL003 cell injection Drug Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Direct Anterior Total Hip Arthroplasty (THA), in Versus Outpatients : A Prospective Monocentric Study in Rennes University Hospital.
Status: TERMINATED
Conditions: Direct Anterior Total Hip Arthroplasty
Interventions: PROCEDURE: Direct Anterior Total Hip Arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Servo-Ventilation on CO2 Regulation and Heart Rate Variability
Status: UNKNOWN
Conditions: Sleep Apnea, Mixed|Heart Failure
Interventions: DEVICE: BiPAP AutoSV Advanced System One|DEVICE: Dreamstation BiPaP AutoSV|DEVICE: ResMed S7 VPAP Adapt Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Sedation Versus Daily Interruption of Sedation in Mechanically Ventilated Patients
Status: COMPLETED
Conditions: Mechanical Ventilation
Interventions: PROCEDURE: Intermittent sedation|PROCEDURE: Daily interruption of sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Multiple Doses Intravitreal Microplasmin for Treatment of Patients With Vitreomacular Traction (MIVI-IIt)
Status: COMPLETED
Conditions: Vitreomacular Traction
Interventions: DRUG: ocriplasmin|DRUG: ocriplasmin|DRUG: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-GITR/Anti-PD1/Stereotactic Radiosurgery, in Recurrent Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: INCMGA00012|DRUG: INCAGN01876|DRUG: SRS|PROCEDURE: Brain surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Rosuvastatin and Enoxaparin Thromboprophylaxis Following Ovarian Cancer Surgery (O-STAT Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Enoxaparin|DRUG: Enoxaparin + Rosuvastatin|OTHER: Thromboprophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clozapine Versus Chlorpromazine for Treatment-Unresponsive Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Clozapine|DRUG: Chlorpromazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Mélisses Garden: Effect on Anxious State in Adult Patients Hospitalized in Psychiatry
Status: COMPLETED
Conditions: Psychiatric Decompensation
Interventions: OTHER: Usual care|BEHAVIORAL: Hortitherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: E.V.O.L.V.E. Trial™: EValuation Of Cinacalcet Hydrochloride (HCl) Therapy to Lower CardioVascular Events
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism|Chronic Kidney Disease
Interventions: DRUG: Cinacalcet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultraslow Full-power SWL Versus Slow Power-ramping SWL in Stones With High Attenuation Value
Status: COMPLETED
Conditions: Renal Stones
Interventions: PROCEDURE: SWL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Oral Mifepristone as Salvage Therapy in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Mifepristone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Tuohy Needle and Quincke Needle During S1 Transforaminal Epidural Injection
Status: RECRUITING
Conditions: S1 Transforaminal Epidural Block
Interventions: DEVICE: Tuohy needle group|DEVICE: Quincke needle group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Prevention of Diabetes Mellitus Type 2
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Nutritional and Metabolic Diseases|Liver Fat|Insulin Sensitivity
Interventions: BEHAVIORAL: Caloric restriction|BEHAVIORAL: no red meat|BEHAVIORAL: Increased fiber intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ledipasvir/Sofosbuvir in Adults With Chronic Hepatitis C Virus (HCV) Infection Who Are on Dialysis for End Stage Renal Disease
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: LDV/SOF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AWARE: Management of ADHD in Autism Spectrum Disorder
Status: RECRUITING
Conditions: ADHD|Autism Spectrum Disorder
Interventions: DRUG: Randomization to either Amphetamine (AMP) class of stimulant medication or Methylphenidate (MPH) class of stimulant medication|DRUG: Randomization to either Alpha 2 agonist class of medication or alternate class of stimulant.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effectiveness of Smartphone Application on the Serevity of Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: BEHAVIORAL: Smartphone Application with lifestyle modification Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Efficacy of Autogenous Dentin Graft in Mandibular Wisdom Tooth Extraction
Status: ACTIVE_NOT_RECRUITING
Conditions: Periodontal Pocket|Swelling Lips & Face|Trismus|Pain, Acute
Interventions: PROCEDURE: Autogenous dentin graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Pharmacokinetics, Tolerability, Safety of SB012 Intrarectally Applied in Active Ulcerative Colitis Patients
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: DRUG: SB012|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Optimal Intraoperative Supplemental Oxygen Administration During Minimally Invasive Esophagectomy
Status: UNKNOWN
Conditions: Oxygenation Index
Interventions: PROCEDURE: low supplemental oxygen concentration|PROCEDURE: high supplemental oxygen concentration (conventional)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Nyaditum Resae® Probiotic to Protect From Tuberculosis
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DIETARY_SUPPLEMENT: Nyaditum resae® 10e4|DIETARY_SUPPLEMENT: Nyaditum resae® 10e5|OTHER: Distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: p53MVA Vaccine and Gemcitabine Hydrochloride in Treating Patients With Recurrent Ovarian Epithelial Cancer
Status: COMPLETED
Conditions: Recurrent Ovarian Epithelial Cancer|Recurrent Fallopian Tube Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: BIOLOGICAL: modified vaccinia virus ankara vaccine expressing p53|DRUG: gemcitabine hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prenatal DHA and Neurofunctional Development
Status: COMPLETED
Conditions: Use and Dose of Prenatal DHA Supplementation
Interventions: DIETARY_SUPPLEMENT: DHA 200mg|DIETARY_SUPPLEMENT: DHA 800mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER