pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM)
Status: COMPLETED
Conditions: Arrhythmia|Cardiovascular Diseases|Death, Sudden, Cardiac|Heart Diseases|Tachycardia, Ventricular|Ventricular Arrhythmia|Ventricular Fibrillation
Interventions: PROCEDURE: electrophysiology|PROCEDURE: electrocardiography, ambulatory|DRUG: imipramine|DRUG: mexiletine|DRUG: procainamide|DRUG: quinidine|DRUG: sotalol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Bioequivalence And Food Effect Study Comparing The Commercial Formulation Of Crizotinib To Its Clinical Study Formulations And Commercial Formulation With Or Without Food In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Family Help Program: Pediatric Recurrent Headache and Abdominal Pain
Status: COMPLETED
Conditions: Pediatric Recurrent Headache & Abdominal Pain
Interventions: BEHAVIORAL: FHP Pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Use of Risk Scores in Reducing Important Clinical Outcomes in Hospitalized Medical Ill Patients
Status: COMPLETED
Conditions: Prevention of Venous Thromboembolism
Interventions: OTHER: Application of Padua and IMPROVE Bleeding scores
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation the Neurocognitive Functions Among Children With Enlargement Adenoid and Tonsils, Before and After Tonsillectomy or Adenotonsillectomy
Status: UNKNOWN
Conditions: Child Neurocognitive Function
Interventions: DIAGNOSTIC_TEST: neuro trax system and a neurology test.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of AS1404 With Docetaxel in Patients With Hormone Refractory Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: AS1404 (DMXAA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial : Complications of in the Bag IOL Versus Optic Capture of IOL in Pediatric Cataract Surgery
Status: COMPLETED
Conditions: Posterior Capsule Opacification|Postoperative Complications
Interventions: PROCEDURE: cataract surgery|PROCEDURE: Intraocular lens implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Phase I Study With LEO 32731 and Midazolam in Healthy Male Subjects
Status: TERMINATED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Midazolam|DRUG: LEO 32731
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Immunogenicity Study of Na-GST-1 With or Without CpG
Status: COMPLETED
Conditions: Hookworm Infection|Hookworm Disease
Interventions: BIOLOGICAL: Na-GST-1/Alhydrogel®|BIOLOGICAL: CpG 10104
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Preventing Pelvic Floor Dysfunction With Pelvic Floor Exercises
Status: ACTIVE_NOT_RECRUITING
Conditions: Prevention Pelvic Muscle Dysfunction
Interventions: OTHER: Standard pelvic floor exercises|OTHER: Involuntary reflexive pelvic floor exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Umbilical Cord-Derived Mesenchymal Stem Cell (VCELL 1) for Male Patients With Sexual Deficiency
Status: RECRUITING
Conditions: Sexual Dysfunction Male
Interventions: BIOLOGICAL: Umbilical Cord-Derived Mesenchymal Stem Cell for Male Patients with Sexual Deficiency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trial To Assess The Safety And Tolerability Of Lucinactant For Inhalation In Preterm Neonates 26 to 28 Weeks PMA
Status: TERMINATED
Conditions: Respiratory Distress Syndrome
Interventions: COMBINATION_PRODUCT: Lucinactant for inhalation|DEVICE: nCPAP alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expiratory Muscle Training for Persons With Neurodegenerative Disease
Status: COMPLETED
Conditions: Parkinson's Disease|Multiple Sclerosis
Interventions: DEVICE: EMST|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Study Assessing the Efficacy and Safety of Anti-Spike SARS CoV-2 Monoclonal Antibodies for Prevention of SARS CoV-2 Infection Asymptomatic in Healthy Adults and Adolescents Who Are Household Contacts to an Individual With a Positive SARS-CoV-2 RT-PCR Assay
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: REGN10933 + REGN10987|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess the Photosensitisation and Photoallergy Potential of a Cosmetic Facial Product in Healthy Participants
Status: COMPLETED
Conditions: Skin Care
Interventions: OTHER: Facial micellar cleanser|OTHER: Saline Solution: Sodium Chloride (NaCl; 0.9%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: GlideSheath Slender® Versus Conventional 5Fr Arterial Sheath in Coronary Angiography Through the Distal Radial Artery
Status: COMPLETED
Conditions: Arterial Access|Coronary Angiography|Radial Artery Occlusion
Interventions: DEVICE: GlideSheath Slender 5Fr arterial sheath|DEVICE: Conventional 5Fr arterial sheath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Treatment Protocol for Hemiplegic Shoulder Pain
Status: COMPLETED
Conditions: Stroke|Hemiplegia|Shoulder Pain
Interventions: OTHER: Standard education/exercises for hemiplegic shoulder pain|OTHER: Three dimensional Scapular-Humeral Mobilizations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mobile Technology to Extend Clinic-based Counseling for HIV+s in Uganda
Status: COMPLETED
Conditions: Alcohol Use, Unspecified|HIV/AIDS
Interventions: BEHAVIORAL: In-person counseling session|BEHAVIORAL: Live phone call booster session|BEHAVIORAL: Technology (IVR or SMS) booster session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Ampligen in Patients With Post-COVID Conditions
Status: COMPLETED
Conditions: Post COVID-19 Condition|Long COVID
Interventions: DRUG: Rintatolimod|OTHER: Placebo / Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Developing and Testing Motherly App: a Smartphone Application to Promote Mothers' Mental Health
Status: WITHDRAWN
Conditions: Maternal Depression
Interventions: BEHAVIORAL: Motherly App|BEHAVIORAL: Educational App (Active Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study Assessing Idrabiotaparinux Sodium Injections Once-weekly in Pulmonary Embolism Therapeutic Approach
Status: COMPLETED
Conditions: Embolism|Thrombosis
Interventions: DRUG: Idrabiotaparinux sodium|DRUG: Warfarin|DRUG: Placebo (for idrabiotaparinux sodium)|DRUG: Avidin|DRUG: Placebo (for warfarin)|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Program evaLuating the Autoimmune Disease iNvEstigational Drug cT-p13 in AS Patients(PLANETAS)
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Taxotere in Combination With Exisulind in Non-Small Cell Lung Cancer (NSCLC) Patients
Status: COMPLETED
Conditions: NSCLC
Interventions: DRUG: Exisulind
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate PM01183 in Combination With Olaparib in Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Cancer|Ovarian Cancer|Endometrial Cancer|Breast Cancer
Interventions: DRUG: PM01183 + olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) Plus COPEGUS (Ribavirin) in Patients With Chronic Hepatitis C (CHC) Genotype 1 and Human Immunodeficiency Virus-1 (HIV-1) Co-infection
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Peginterferon alfa-2a|DRUG: Ribavirin|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Obesity With Prediabetes
Status: NOT_YET_RECRUITING
Conditions: Obesity|Pre-diabetes
Interventions: DEVICE: Acupuncture|DEVICE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Treatment Study of Certolizumab Pegol (CDP870) as Add-on Medication to Methotrexate in Japanese Rheumatoid Arthritis (RA) Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Certolizumab pegol|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Efficacy and Safety of Canagliflozin in Children and Adolescents (>=10 to <18 Years) With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Canagliflozin 100 mg|DRUG: Canagliflozin 300 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Activity of Masitinib (AB1010) in Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: masitinib (AB1010)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 90-Day Online Substance Use Program
Status: UNKNOWN
Conditions: Addictive Behavior|Alcohol Use Disorder|Alcohol Abuse|Drug Abuse|Drug Use Disorders
Interventions: BEHAVIORAL: Treatment - Workit Health Online Program|BEHAVIORAL: Control - Resource List
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Fixation for Distal Radius Fractures
Status: NOT_YET_RECRUITING
Conditions: Distal Radius Fracture
Interventions: DEVICE: Minimal invasive surgical fixation of distal radius Fractures
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterizing Chemo-Radiotherapy Treatment-Related Cardiac Changes
Status: COMPLETED
Conditions: Clinical Stage 0 Esophageal Adenocarcinoma AJCC V8|Clinical Stage 0 Esophageal Squamous Cell Carcinoma AJCC V8|Clinical Stage I Esophageal Adenocarcinoma AJCC V8|Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC V8|Clinical Stage II Esophageal Adenocarcinoma AJCC V8|Clinical Stage II Esophageal Squamous Cell Carcinoma AJCC V8|Clinical Stage IIA Esophageal Adenocarcinoma AJCC V8|Clinical Stage IIB Esophageal Adenocarcinoma AJCC V8|Clinical Stage III Esophageal Adenocarcinoma AJCC V8|Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC V8|Localized Esophageal Carcinoma|Localized Lung Carcinoma|Pathologic Stage 0 Esophageal Adenocarcinoma AJCC V8|Pathologic Stage 0 Esophageal Squamous Cell Carcinoma AJCC V8|Pathologic Stage I Esophageal Adenocarcinoma AJCC V8|Pathologic Stage I Esophageal Squamous Cell Carcinoma AJCC V8|Pathologic Stage IA Esophageal Adenocarcinoma AJCC V8|Pathologic Stage IA Esophageal Squamous Cell Carcinoma AJCC V8|Pathologic Stage IB Esophageal Adenocarcinoma AJCC V8|Pathologic Stage IB Esophageal Squamous Cell Carcinoma AJCC V8|Pathologic Stage IC Esophageal Adenocarcinoma AJCC V8|Pathologic Stage II Esophageal Adenocarcinoma AJCC V8|Pathologic Stage II Esophageal Squamous Cell Carcinoma AJCC V8|Pathologic Stage IIA Esophageal Adenocarcinoma AJCC V8|Pathologic Stage IIA Esophageal Squamous Cell Carcinoma AJCC V8|Pathologic Stage IIB Esophageal Adenocarcinoma AJCC V8|Pathologic Stage IIB Esophageal Squamous Cell Carcinoma AJCC V8|Pathologic Stage III Esophageal Adenocarcinoma AJCC V8|Pathologic Stage III Esophageal Squamous Cell Carcinoma AJCC V8|Pathologic Stage IIIA Esophageal Adenocarcinoma AJCC V8|Pathologic Stage IIIA Esophageal Squamous Cell Carcinoma AJCC V8|Pathologic Stage IIIB Esophageal Adenocarcinoma AJCC V8|Pathologic Stage IIIB Esophageal Squamous Cell Carcinoma AJCC V8|Postneoadjuvant Therapy Stage I Esophageal Adenocarcinoma AJCC V8|Postneoadjuvant Therapy Stage I Esophageal Squamous Cell Carcinoma AJCC V8|Postneoadjuvant Therapy Stage II Esophageal Adenocarcinoma AJCC V8|Postneoadjuvant Therapy Stage II Esophageal Squamous Cell Carcinoma AJCC V8|Postneoadjuvant Therapy Stage III Esophageal Adenocarcinoma AJCC V8|Postneoadjuvant Therapy Stage III Esophageal Squamous Cell Carcinoma AJCC V8|Postneoadjuvant Therapy Stage IIIA Esophageal Adenocarcinoma AJCC V8|Postneoadjuvant Therapy Stage IIIA Esophageal Squamous Cell Carcinoma AJCC V8|Postneoadjuvant Therapy Stage IIIB Esophageal Adenocarcinoma AJCC V8|Postneoadjuvant Therapy Stage IIIB Esophageal Squamous Cell Carcinoma AJCC V8|Stage 0 Lung Cancer AJCC V8|Stage I Lung Cancer AJCC V8|Stage IA1 Lung Cancer AJCC V8|Stage IA2 Lung Cancer AJCC V8|Stage IA3 Lung Cancer AJCC V8|Stage IB Lung Cancer AJCC V8|Stage II Lung Cancer AJCC V8|Stage IIA Lung Cancer AJCC V8|Stage IIB Lung Cancer AJCC V8|Stage III Lung Cancer AJCC V8|Stage IIIA Lung Cancer AJCC V8|Stage IIIB Lung Cancer AJCC V8|Stage IIIC Lung Cancer AJCC V8
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vaccine Therapy With or Without Recombinant Interleukin-12 Followed by Daclizumab in Treating Patients With Metastatic Melanoma
Status: TERMINATED
Conditions: Recurrent Melanoma|Stage IV Skin Melanoma
Interventions: BIOLOGICAL: NA17.A2 Peptide Vaccine|BIOLOGICAL: Recombinant MAGE-3.1 Antigen|BIOLOGICAL: Recombinant Interleukin-12|BIOLOGICAL: MART-1 Antigen|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab, Belantamab and Dexamethasone in Refractory Multiple Myeloma.
Status: WITHDRAWN
Conditions: Multiple Myeloma, Refractory
Interventions: DRUG: Pembrolizumab|DRUG: Belantamab mafodotin|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EEG Theta-Beta Ratio Neurofeedback-training
Status: COMPLETED
Conditions: Elevated EEG Theta/Beta Ratio
Interventions: OTHER: Neurofeedback|OTHER: Placebo Neurofeedback training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Learn About Novel Hormonal Therapies (NHTs) for Metastatic Castration-sensitive Prostate Cancer (mCSPC) in People Who Were in the Armed Forces
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms
Interventions: DRUG: Novel hormonal therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of OLX10212 in Patients With Neovascular Age-related Macular Degeneration
Status: RECRUITING
Conditions: Neovascular Age-related Macular Degeneration
Interventions: GENETIC: OLX10212 is a cell penetrating asymmetric small interference RNA (cp-asiRNA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Pertuzumab + Trastuzumab + Vinorelbine vs. Placebo + Trastuzumab + Docetaxel in Previously Untreated HER2-positive Metastatic Breast Cancer
Status: WITHDRAWN
Conditions: Advanced Breast Cancer|HER2-positive Breast Cancer
Interventions: DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Vinorelbine|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Abuse Liability of Reduced Nicotine Content Cigarettes in the Context of Concurrent E-Cigarette Use
Status: COMPLETED
Conditions: Nicotine Addiction|Cigarette Smoking
Interventions: DRUG: Smoking research cigarettes with e-cigarette|DRUG: Nicotine discrimination thresholds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: RFA for Flat Type High-grade and Medium-grade Intraepithelial Squamous Neoplasia
Status: TERMINATED
Conditions: Esophageal Squamous Cell Neoplasia (ESCN)
Interventions: DEVICE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Immunogenicity of Intranasal Nanoemulsion Adjuvanted Recombinant Anthrax Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Anthrax
Interventions: BIOLOGICAL: BW-1010: 50 µg - sprayer - IN|BIOLOGICAL: BW-1010: 50 µg - pipette - IN|BIOLOGICAL: BW-1010: 100 µg - sprayer - IN|BIOLOGICAL: BW-1010: 100 µg - pipette - IN|BIOLOGICAL: Saline (Placebo) - sprayer - IN|BIOLOGICAL: Saline (Placebo) - pipette - IN|BIOLOGICAL: BioThrax (positive control) - SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A First in Human Study Using 89Zr-cRGDY Ultrasmall Silica Particle Tracers for Malignant Brain Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain Cancer|Pituitary Adenoma
Interventions: DRUG: 89Zr-DFO-cRGDY-PEG-Cy5-C' dots PET Imaging|OTHER: Blood and Urine samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of AM-111 as Acute Sudden Sensorineural Hearing Loss Treatment
Status: TERMINATED
Conditions: Hearing Loss, Idiopathic Sudden Sensorineural
Interventions: DRUG: AM-111 0.4 mg/ml|DRUG: AM-111 0.8 mg/ml|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microcurrent Device (TIVIC Health)
Status: COMPLETED
Conditions: Chronic Rhinosinusitis
Interventions: DEVICE: Microcurrent TENS device|DEVICE: Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Exenatide Once Weekly in Adolescents With Type 2 Diabetes
Status: COMPLETED
Conditions: Children and Adolescent With Type 2 Diabetes
Interventions: DRUG: Exenatide Once Weekly|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of Indinavir Plus Ritonavir Plus Two NRTIs in HIV-Infected Patients Who Need Early Intervention Treatment
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Neonatal Cerebral Oxygenation and Changes in CPAP Flow Pressure - Evaluation With INVOS Oximeter
Status: COMPLETED
Conditions: Cerebral Oxygenation
Interventions: PROCEDURE: Cerebral NIRS Oximetry + CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Benzbromarone-Controlled, Double-Blind, Comparative Study of FYU-981 in Hyperuricemia With or Without Gout
Status: COMPLETED
Conditions: Hyperuricemia With or Without Gout
Interventions: DRUG: FYU-981|DRUG: Benzbromarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimising the Efficacy, Patient Perception and Uptake of an Exercise Programme in People in Intermittent Claudication
Status: COMPLETED
Conditions: Vascular Disease|Intermittent Claudication
Interventions: OTHER: Supervised exercise programme
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Inflammatory Markers Dynamics in Response to Extra-corporeal Membrane Oxygenator Decannulation
Status: UNKNOWN
Conditions: Inflammatory Markers Changes in Response to Extra-corporeal Membrane Oxygenator Decannulation
Interventions: DIAGNOSTIC_TEST: Inflammatory makers that will include Interleukins (IL); IL1, IL2, IL6 and TNF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Ikervis for DED Due to GVHD Post Allo-HSCT
Status: UNKNOWN
Conditions: Leukemia (Both ALL and AML)|MDS-EB-1
Interventions: DRUG: Cyclosporine Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Development of Ingestible Biosensors to Enhance PrEP Adherence in Substance Users (PrEPSteps)
Status: COMPLETED
Conditions: HIV Infections|Substance Use Disorders
Interventions: BEHAVIORAL: PrEPsteps|DEVICE: Digital pill|DRUG: Truvada
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of SHR-1918 in Patients With Hyperlipidemia
Status: NOT_YET_RECRUITING
Conditions: Hyperlipidemia
Interventions: DRUG: SHR-1918; SHR-1918 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of VB10.16 Alone or in Combination With Atezolizumab in Patients With Advanced Cervical Cancer.
Status: RECRUITING
Conditions: HPV-Related Cervical Carcinoma|HPV-Related Malignancy|Cervical Cancer
Interventions: BIOLOGICAL: VB10.16|DRUG: Atezolizumab Injection [Tecentriq]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effects of Music Interventions on Hospitalised People With Dementia
Status: UNKNOWN
Conditions: Dementia|Alzheimer's Disease|Dementia, Vascular|Lewy Body Disease
Interventions: PROCEDURE: Music Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Dose-dense Biweekly Docetaxel Combined With 5-fluorouracil as First-line Treatment in Advanced Gastric Cancer
Status: COMPLETED
Conditions: Gastric Adenocarcinoma
Interventions: DRUG: Docetaxel|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Description of the Evolution of a Cohort of Adolescents With Type 1 Diabetes Following Their Participation in Therapeutic Education Program Based on Social Cognitive Theory: Socio-cognitive Profile, Physiological Behaviour of Therapeutic Adherence and Quality of Life
Status: UNKNOWN
Conditions: Type 1 Pediatric Diabetes
Interventions: OTHER: therapeutic education program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: REducing Diabetic macrovascUlar Complications duE to Peripheral Arterial Disease- REDUCE-PAD
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2|Peripheral Arterial Disease
Interventions: BIOLOGICAL: MEI6570
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study
Status: RECRUITING
Conditions: Anal Basaloid Carcinoma|Anal Canal Cloacogenic Carcinoma|Anal Canal Squamous Cell Carcinoma|Anal Margin Squamous Cell Carcinoma|Stage I Anal Cancer AJCC v8|Stage IIA Anal Cancer AJCC v8
Interventions: DRUG: Capecitabine|DRUG: Fluorouracil|RADIATION: Intensity-Modulated Radiation Therapy|DRUG: Mitomycin|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sildenafil on Diffusion Capacity in Patients With PH and Parenchymal Lung Disease
Status: COMPLETED
Conditions: Diffuse Parenchymal Lung Disease|Pulmonary Hypertension
Interventions: DRUG: Oral sildenafil 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Outcome of Perioperative Immune Enhancing Nutrition in Patients Undergoing Radical Cystectomy
Status: COMPLETED
Conditions: Cancer, Bladder|Cystostomy; Complications
Interventions: DIETARY_SUPPLEMENT: Neo-mune powder (otsuka pharmaceutical)|DRUG: Dipeptiven solution (Fresenius Kabi pharmaceutical)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Atorvastatin on Endothelial Dysfunction and Albuminuria in Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease|Sickle Cell Nephropathy
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Netarsudil and Timolol on Retinal Blood Vessel Density and Visual Acuity
Status: WITHDRAWN
Conditions: OAG - Open-Angle Glaucoma|OHT - Ocular Hypertension
Interventions: OTHER: Netarsudil 0.02% QD|OTHER: Timolol maleate 0.5% BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: To Assess the Safety of Ciclesonide, Applied as a Nasal Spray at Three Dose Levels, in the Treatment of Perennial Allergic Rhinitis in Pediatrics (BY9010/M1-405)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial|Hay Fever
Interventions: DRUG: Ciclesonide nasal|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Diaphragm Stretching Technique on Nonspecific Low Back Pain
Status: NOT_YET_RECRUITING
Conditions: Nonspecific Low Back Pain
Interventions: OTHER: Placebo Technique|OTHER: Diaphragm Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Fruit and Vegetables in PKU
Status: COMPLETED
Conditions: Phenylketonurias
Interventions: OTHER: Phase B - Extra 1 Phe exchange from fruits/vegetables containing Phe from 76-100mg/100g|OTHER: Phase C - Extra 2 Phe exchanges from fruits/vegetables containing Phe from 76-100mg/100g|OTHER: Phase D - Extra 1 Phe exchange from milk or yoghurt|OTHER: Phase E - Extra 2 Phe exchanges from milk or yoghurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Investigation of a New Stoma Product for People With a Stoma
Status: COMPLETED
Conditions: Peristomal Skin Complication
Interventions: DEVICE: Non-Conformité Européene marked product|DEVICE: Conformité Européene marked competitor products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase IV Study to Evaluate the Efficacy of Lagricel® Ofteno PF Compared to Thealoz® Duo After Photorefractive Keratectomy (PRK)
Status: COMPLETED
Conditions: Photorefractive Keratectomy|Corneal De-epithelialization
Interventions: DRUG: Sodium Hyaluronate Ophthalmic 0.4%|DRUG: Trehalose 3% / Sodium Hyaluronate Ophthalmic 0.15%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab-Sacituzumab Govitecan Combination to Treat High-risk, Localized Bladder Cancer
Status: ENROLLING_BY_INVITATION
Conditions: Muscle-invasive Urothelial Carcinoma of the Bladder
Interventions: DRUG: Pembrolizumab 25 mg/1 ML Intravenous Solution [KEYTRUDA]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trauma and Trauma-Focused Therapy in the University of Kentucky SMART Clinic
Status: COMPLETED
Conditions: PTSD|Opioid-use Disorder|Substance Use Disorders
Interventions: BEHAVIORAL: Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure (COPE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Robotic-Assisted Versus Conventional Total Knee Arthroplasty(TKA)
Status: COMPLETED
Conditions: Arthritis|Knee Arthropathy|Robotics
Interventions: PROCEDURE: Robotic-assisted TKA|PROCEDURE: Conventional TKA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Intraperitoneal Pain Management Following Laparoscopic Cholecystectomy
Status: RECRUITING
Conditions: Post Operative Pain
Interventions: DRUG: Granisetron 1 Mg/mL Intravenous Solution|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect on Tumor Perfusion of a Chemotherapy Combining Gemcitabine and Vismodegib Before Surgery in Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Adenocarcinoma Resectable
Interventions: DRUG: gemcitabine|DRUG: Vismodegib|PROCEDURE: Neoadjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Fluorescein Sodium Dosage for the Detection of Gastric Intestinal Metaplasia
Status: UNKNOWN
Conditions: Gastric Intestinal Metaplasia
Interventions: DRUG: lower fluorescein sodium dosage 0.02ml/kg|DRUG: conventional fluorescein sodium dosage 0.1ml/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness and Cost-effectiveness of iCBT-I in Clinical Settings
Status: RECRUITING
Conditions: Chronic Insomnia
Interventions: BEHAVIORAL: internet-delivered cognitive-behavioral therapy for insomnia (iCBT-I)|OTHER: Care as usual (CAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bioequivalence Study of Lisinopril Tablets 40 mg Under Fasting Condition
Status: COMPLETED
Conditions: Fasting
Interventions: DRUG: Lisinopril Tablets 40 mg|DRUG: Lisinopril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Natural History Study of Infants With Adrenal Masses Found on Prenatal and/or Neonatal Imaging
Status: COMPLETED
Conditions: Adrenocortical Carcinoma|Localized Resectable Neuroblastoma|Precancerous Condition
Interventions: PROCEDURE: computed tomography|PROCEDURE: 3-Tesla magnetic resonance imaging|PROCEDURE: Abdominal Sonogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Pasteurized Akkermansia Muciniphila on Insulin Resistance in Otherwise Healthy Subjects With Dysglycaemia
Status: COMPLETED
Conditions: Metabolic Syndrome|Pre-diabetes|Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Pasteurized A. muciniphila|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Durvalumab as Maintenance Following Chemoradiation for Unresectable Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Empowerment Program for New Graduated Nurses
Status: ACTIVE_NOT_RECRUITING
Conditions: Empowerment
Interventions: OTHER: Training Program to be Developed for Empowering New Graduated Nurses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Rivaroxaban in the Prevention of Venous Thromboembolism in Glioma Patients
Status: RECRUITING
Conditions: Glioma, Malignant
Interventions: DRUG: Rivaroxaban 10 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Herbal Extract Granules Combined With Probiotics on Irritable Bowel Syndrome With Diarrhea
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Herbal extract granule and probiotics|DIETARY_SUPPLEMENT: Herbal extract granule and placebo probiotics|DIETARY_SUPPLEMENT: Placebo herbal extract granule and probiotics|DIETARY_SUPPLEMENT: Placebo herbal extract granule and placebo probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lessening the Impact of Fatigue in Inflammatory Rheumatic Diseases
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Lupus Erythematosus, Systemic|Axial Spondyloarthritis|Psoriatic Arthritis|Sjogren's Syndrome
Interventions: BEHAVIORAL: Usual Care|BEHAVIORAL: Cognitive behavioural approach|BEHAVIORAL: Personalised Exercise Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cerebellar rTMS Theta Burst for Postural Instability in Progressive Supranuclear Palsy
Status: COMPLETED
Conditions: Progressive Supranuclear Palsy|Fall|Gait, Rigid|Parkinsonism
Interventions: DEVICE: repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cells for the Improvement of Erectile and Cardiac Function in Aging Men
Status: WITHDRAWN
Conditions: Erectile Dysfunction|Cardiac Disease
Interventions: BIOLOGICAL: ARM 1: AdMSC: adipose stem cells|OTHER: ARM 2: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A 2 Year Trial of Patients With Type 2 Diabetes Focusing on Cardiovascular Diagnostics and Metabolic Control
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Combined lifestyle intervention and optimisation of pharmacological treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Comparing Use of Manual and Power Bone Marrow Aspiration and Biopsy Devices in Children
Status: COMPLETED
Conditions: Bone Marrow Aspiration and Biopsy Specimen Collection
Interventions: DEVICE: Manual bone marrow aspiration and biopsy device|DEVICE: Powered bone marrow aspiration and biopsy device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Open-label Study to Investigate the Safety, Tolerability, PK, and Pharmacodynamics of the AKT Inhibitor GSK690693
Status: TERMINATED
Conditions: Cancer
Interventions: DRUG: GSK690693
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Botulinum Toxin Type A to Treat Lower Urinary Symptoms Due to Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: BIOLOGICAL: botulinum toxin Type A|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cancer and Disorders of Cognitive Functions and Quality of Life: "Cognitive Rehabilitation in Patients Suffering From Cancer and Treated With Chemotherapy"
Status: COMPLETED
Conditions: Cancer
Interventions: OTHER: Cognitive exams|OTHER: standardized cognitive rehabilitation|OTHER: Standardized home exercise|OTHER: Follow up by phone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Oral Budesonide vs. Oral Mesalazine in Active Crohn's Disease (CD)
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: budesonide|DRUG: mesalazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HPV Self-sampling for Women Who do Not Attend Cervical Cancer Screening Programme
Status: RECRUITING
Conditions: Papillomavirus Infections|Early Detection of Cancer|Cervix Cancer|Self-Examination
Interventions: DEVICE: Directly mailed self-sampling kit to collect a vaginal sample|DEVICE: Mailed self-sampling kit to collect a vaginal sample after opt-in prodecure|DIAGNOSTIC_TEST: Standard of care - screening in a clinical setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Implementing Post Operative Enhanced Recovery on Perforated Peptic Ulcer Surgery Outcomes
Status: COMPLETED
Conditions: Emergent Surgery|Perforated Peptic Ulcer
Interventions: PROCEDURE: Post operative enhanced recovery elements
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of GC007F CAR-T Cell Immunotherapy for Relapsed or Refractory B- ALL
Status: COMPLETED
Conditions: B-cell Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: GC007F
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Two Treatment Regimens of Topical MOB015 in Adults With Distal Subungual Onychomycosis
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DRUG: MOB015
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Compared With Dexmedetomidine as an Adjuvant to Ropivacaine for Supraclavicular Brachial Plexus Block
Status: COMPLETED
Conditions: Brachial Plexus Block
Interventions: DRUG: Ropivacaine and Normal saline|DRUG: Ropivacaine and Dexamethasone|DRUG: Ropivacaine and Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Selinexor and Chemotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Recurrent Adult Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia
Interventions: DRUG: mitoxantrone hydrochloride|DRUG: etoposide|DRUG: cytarabine|DRUG: selinexor|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Application of Pulsed RF and Steroids to the DRG for PHN
Status: COMPLETED
Conditions: Postherpetic Neuralgia|Chronic Pain
Interventions: PROCEDURE: Epidural steroid|PROCEDURE: PRF plus steroids injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Immunoglobulin Plus Infliximab for the Early Regression of Coronary Artery Lesion in Kawasaki Disease
Status: WITHDRAWN
Conditions: Kawasaki Disease
Interventions: DRUG: IVIG|DRUG: Aspirin|DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Understanding and Optimizing Care for Young Adults With Type 1 and Type 2 Diabetes Mellitus Transitioning to Adult Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 1 Diabetes|Type 2 Diabetes
Interventions: OTHER: Diabetes Collaborative Care Model for Young Adults|OTHER: Usual Care Model
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluating the Management of Chronic Pelvic Girdle Pain
Status: COMPLETED
Conditions: Pelvic Girdle Pain
Interventions: DEVICE: customised pelvic support shorts|OTHER: Exercise|OTHER: advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Occupational Therapy Rehabilitation for Frail Elders With Dysphagia
Status: RECRUITING
Conditions: Dysphagia, Oropharyngeal|Deglutition Disorders
Interventions: BEHAVIORAL: ACT-ING program ( Activity-based skill- and strength training to improve ingestion)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Swallowable Cannabigerol Tablets for Sleep Quality In Veterans (Veterans Exploring Cannabigerol for Sleep)
Status: COMPLETED
Conditions: Sleep
Interventions: OTHER: Cannabigerol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate and Longterm Effects of Mulligan Mobilization With and Without Myofascial Release on Pain,Grip Strength and Function in Patients With Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: OTHER: mulligan mobilization|OTHER: myofascial release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Supervised Physical Therapy Versus Unsupervised Home Exercise After Surgery for Lumbar Disc Herniation
Status: COMPLETED
Conditions: Disk Herniated Lumbar|Physiotherapy|Surgery
Interventions: OTHER: No referral for rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PBMT Associated With MCE for Chronic Non- Specific Low Back Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Low Back Pain
Interventions: DEVICE: Placebo PBMT + MCE|DEVICE: Active PBMT + MCE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incidence, Course and Outcome of ABMR in Kidney Transplantation
Status: RECRUITING
Conditions: Antibody-mediated Rejection|Kidney Transplantation|Immunosuppression
Interventions: PROCEDURE: Kidney Transplantation|COMBINATION_PRODUCT: Immunosuppression|PROCEDURE: Nephrectomy (kidney donation)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I/II Study to Evaluate UC1010 Treatment in Premenstrual Dysphoric Disorder (PMDD)
Status: COMPLETED
Conditions: Premenstrual Dysphoric Disorder
Interventions: DRUG: UC1010|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT