pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Alternative Sensory Presentation Formats in Asymptomatic Carotid Stenosis
Status: WITHDRAWN
Conditions: Carotid Stenosis
Interventions: OTHER: Video|OTHER: Video|OTHER: Video|OTHER: Video|OTHER: Video|OTHER: Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: EFFECTIVENESS: Hopewell Hospitalist: A Video Game Intervention to Increase Advance Care Planning by Hospitalists
Status: TERMINATED
Conditions: Advance Care Planning
Interventions: BEHAVIORAL: Hopewell Hospitalist Video Game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Apatinib With Albumin-bound Paclitaxel in Patients With Platinum-resistant Recurrent Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer
Interventions: DRUG: albumin-bound paclitaxel|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Oral and Subcutaneous Vaccination Using a 2nd Generation (E1/E2B/E3-Deleted) Adenovirus Platform in Healthy Volunteers in USA
Status: UNKNOWN
Conditions: Covid19
Interventions: BIOLOGICAL: hAd5-S-Fusion+N-ETSD (Suspension for injection)|DRUG: hAd5-SFusion+ N-ETSD (Oral capsule)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of THDB0206 Compared to Insulin Lispro Injection in Participants With Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: THDB0206 Injection|DRUG: Insulin Lispro Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treadmill Therapy and Brain Injuries
Status: COMPLETED
Conditions: Cerebral Stroke|Hemiplegia|Moderate to Severe Functional Impairments
Interventions: OTHER: Treadmill therapy and conventional walking therapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AML-02: Omacetaxine With Standard-of-Care Induction With Cytarabine & Idarubicin in Newly-Diagnosed AML Patients
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|DRUG: Idarubicin|DRUG: Omacetaxine mepesuccinate|DRUG: Omacetaxine mepesuccinate|DRUG: Omacetaxine mepesuccinate|DRUG: Omacetaxine mepesuccinate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Safety and Effectiveness Study of a New High Repetition Rate Excimer Laser Using LASIK for the Correction of Ammetropia and Presbyopia
Status: UNKNOWN
Conditions: Myopia|Hyperopia|Presbyopia
Interventions: PROCEDURE: Proscan|PROCEDURE: Zyoptix|PROCEDURE: Supracor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of 2 Ribociclib Doses in Combination With Aromatase Inhibitors in Women With HR+, HER2- Advanced Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Ribociclib|DRUG: Anastrozole|DRUG: Letrozole|DRUG: Goserelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Intravenous Imipenem/Cilastatin/XNW4107 in Comparison With Meropenem in Hospitalized Adults With cUTI Including AP (EudraCT no. 2022-000061-40)
Status: NOT_YET_RECRUITING
Conditions: Complicated Urinary Tract Infection Including Acute Pyelonephritis
Interventions: DRUG: Combination of Imipenem/Cilastatin and XNW4107|DRUG: Meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opioid Free Anesthesia in Thoracic Surgery
Status: COMPLETED
Conditions: Thoracic Surgery|Analgesics, Opioid|Anesthesia, Conduction
Interventions: DRUG: Opioid Anesthesia|DRUG: Opioid Free Anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dynamic Muscular Electrical Stimulation Following Anterior Cruciate Ligament Reconstruction in Military Academy Cadets
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Injuries
Interventions: DEVICE: KneeStim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Salbutamol vs Long-acting Muscarinic Antagonists
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Salbutamol|DRUG: LAMA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cryoablation Combined With Tislelizumab Plus Lenvatinib in 1L Treatment of Advanced HCC (CASTLE-10)
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Cryoablation|DRUG: Tislelizumab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single-Dose Subcutaneous Administration of MEDI-528
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: MEDI-528 0.3 mg/kg|BIOLOGICAL: MEDI-528 1 mg/kg|BIOLOGICAL: MEDI-528 3 mg/kg|BIOLOGICAL: MEDI-528 9 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Models of Primary Osteoporosis Screening in Male Veterans
Status: RECRUITING
Conditions: Osteoporosis|Osteopenia|Osteoporotic Fracture
Interventions: BEHAVIORAL: Bone Health Service Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Effect of Different Left Lateral Table Tilt for Elective Cesarean Delivery Under Spinal Anesthesia
Status: COMPLETED
Conditions: Elective Cesarean Section|Spinal Anesthesia
Interventions: DEVICE: 15° and 30° wedge sponges
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Osimertinib and Tegavivint as First-Line Therapy for the Treatment of Metastatic EGFR-Mutant Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Metastatic Lung Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: DRUG: Osimertinib|DRUG: Tegavivint
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Innovative Continuum of Care to Promote Exclusive Breastfeeding
Status: ENROLLING_BY_INVITATION
Conditions: Breastfeeding
Interventions: BEHAVIORAL: Continuum of support on breastfeeding.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Intralesional Injection of Pentoxifylline, Platelet-Rich Plasma, and Combined Pentoxifylline With Platelet-Rich Plasma in Patients With Atrophic Acne Scars
Status: RECRUITING
Conditions: Atrophic Acne Scar
Interventions: DRUG: Pentoxifylline|DRUG: platelet rich plasma|DRUG: combined pentoxifylline and platelet rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypertonic Versus Isotonic Saline Irrigations for Chronic Rhinosinusitis
Status: WITHDRAWN
Conditions: Chronic Rhinosinusitis (Diagnosis)
Interventions: DRUG: Isotonic saline|DRUG: Hypertonic Nasal Wash|DRUG: Fluticasone Propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial of Acupuncture for Knee Osteoarthritis With Differential Functional Status of Acupoints
Status: COMPLETED
Conditions: Acupuncture|Knee Osteoarthritis|Randomized Controlled Trial
Interventions: OTHER: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of THC and Alcohol on Driving Performance
Status: WITHDRAWN
Conditions: Cannabis|Alcohol Drinking|Accident, Traffic
Interventions: DRUG: THC 0|DRUG: THC 5|DRUG: THC 10|OTHER: BAC 0|OTHER: BAC .025|OTHER: BAC .049
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact of Intravenous Anaesthesia on Angiogenesis in Patients With Breast Cancer (TIVA/TCI-BC)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Lidocaine|DRUG: Sevoflurane|DRUG: TIVA-TCI|DRUG: Acetaminophen|DRUG: Tramadol|DRUG: Neostigmine|DRUG: Atropine|DEVICE: BIS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Changes in Blood Flow in the Application of Magnetic Tape in Patients With Low Back Pain. RCT
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DIAGNOSTIC_TEST: Tape application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Compare the Solifenacin/Tamsulosin Combination Therapy With Tamsulosin Monotherapy for LUTS Due to BPH
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms|Benign Prostatic Hyperplasia
Interventions: DRUG: Tamsulosin 0.2mg + Solifenacin 5mg|DRUG: Tamsulosin 0.2mg + Placebo(Solifenacin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Heartrate Variability During Conventional and Variable Pressure Support Mechanical Ventilation
Status: UNKNOWN
Conditions: Mechanical Ventilation Complication
Interventions: PROCEDURE: Variable-PS|PROCEDURE: SPN-CPAP/PS|PROCEDURE: Variable-PS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rotigotine Effect on Nocturnal Hypokinesia Compares to Placebo Control: A Quantitative Assessment by Wearable Sensors
Status: UNKNOWN
Conditions: Nocturnal Hypokinesia
Interventions: DRUG: Rotigotine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Teeth Whitening Product Offerings in Adults
Status: COMPLETED
Conditions: Tooth Discoloration
Interventions: OTHER: Hydrogen peroxide teeth whitening gel|DEVICE: GLO Brilliant Teeth Whitening Device|DEVICE: GLO Lit Teeth Whitening Device|DEVICE: GLO Science Professional Teeth Whitening Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention of Suxiao Jiuxin Pill on Instability of Vulnerable Plaque in Acute Myocardial Infarction
Status: NOT_YET_RECRUITING
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Suxiao Jiuxin Pills|DRUG: The placebo of Suxiao Jiuxin Pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Digital Mental Health Service for Non-Treatment Seeking Young Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression|Anxiety|Suicidal Ideation
Interventions: BEHAVIORAL: Adaptive messaging intervention|BEHAVIORAL: Non-personalized messaging intervention|BEHAVIORAL: Coaching|BEHAVIORAL: Psychoeducational links
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Electroacupuncture on P6 Acupoint on Hypertensive Patients.
Status: UNKNOWN
Conditions: Hypertension
Interventions: PROCEDURE: Acupuncture|PROCEDURE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parent Intervention to Prevent Disordered Eating in Children With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Disordered Eating|Children, Only|Eating Disorders|Parents
Interventions: BEHAVIORAL: Parental psychoeducational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Role of 68Gallium PSMA-11 in Enhancing Diagnosis of Primary and Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Prostate Cancer Metastatic
Interventions: DRUG: 68Ga PSMA-11 injection|PROCEDURE: Positron Emission Tomography/Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fu-zheng-qu-zhuo Oral Liquid Improves Renal Function in Patients of CKD Stage 3 and 4
Status: COMPLETED
Conditions: Stage 3 Chronic Kidney Disease|Stage 4 Chronic Kidney Disease
Interventions: DRUG: Fu-zheng-qu-zhuo (FZQZ) oral liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intranasal Oxytocin on Emphatic Abilities in Patients With Post Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: DRUG: syntocinon nasal spray|DRUG: placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise for Adolescents Following Sport-Related Concussion: A Randomized Control Trial
Status: UNKNOWN
Conditions: Sport-related Concussion|Concussion|Mild Traumatic Brain Injury (MTBI)
Interventions: BEHAVIORAL: Active Rehabilitation Program|BEHAVIORAL: Treatment-as-usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Fish Oil Supplementation and a Montelukast on EIB and Airway Inflammation in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: Active Montelukast + Fish Oil Placebo|OTHER: Active Fish Oil + Montelukast Placebo|OTHER: Active Montelukast + Active Fish Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Interest on Cervical Ultrasound Exploration for Association With Difficult Intubation
Status: COMPLETED
Conditions: Intubation; Difficult
Interventions: PROCEDURE: Ultrasound cervical exploration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy Study of BCD-066 Compared to Aranesp® for Anemia Treatment in Chronic Kidney Disease Patients
Status: COMPLETED
Conditions: Chronic Kidney Disease|End Stage Renal Failure on Dialysis|Anemia
Interventions: DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bortezomib, Lenalidomide, and Dexamethasone in Treating Patients With Multiple Myeloma Undergoing Stem Cell Transplant
Status: TERMINATED
Conditions: Refractory Plasma Cell Myeloma
Interventions: DRUG: Bortezomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Urethral Catheter Immobilization Device to Reduce Catheter-Related Discomfort
Status: WITHDRAWN
Conditions: Urinary Catheter-Related Discomfort
Interventions: DEVICE: Urethral catheter immobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hernia Belt in Laparoscopic Inguinal Hernia Repair
Status: RECRUITING
Conditions: Hernia, Inguinal|Recurrence|Seroma Following Procedure|Pain, Postoperative|Quality of Life
Interventions: PROCEDURE: Hernia belt compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamic Treatment Regiments for Glucocorticoid Tapering
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: 15-day taper prednisone|DRUG: 150-day taper prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Reduction in Spinal-induced Hypotension With Ondansetron in Parturients Undergoing Caesarean Section
Status: COMPLETED
Conditions: Hypotension
Interventions: DRUG: Ondansetron|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study of Boceprevir for the Treatment of Genotype 6 HCV
Status: UNKNOWN
Conditions: Chronic Hepatitis C
Interventions: DRUG: Victrelis® (boceprevir) 800mg by mouth, TID (200 mg tablets)|DRUG: Peg-Intron® (peginterferon-α-2b), 1.5ug/kg sc injection|DRUG: Rebetol® (ribavirin), 1000/1200mg by mouth daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Early Enteral Nutrition in Severe Stroke
Status: TERMINATED
Conditions: Severe Stroke|Acute Stroke|Dysphagia
Interventions: OTHER: Initial enteral feeding|DRUG: metoclopramide or mosapride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Risk Factors for Cut-out After Internal Fixation of Trochanteric Fractures in Elderly Subjects.
Status: COMPLETED
Conditions: Proximal Femoral Fracture
Interventions: OTHER: Analysis of associated factors for cut-out in internal fixation of extracapsular proximal femoral fracture.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study of Hydroxytyrosol (HT) in Mitochondrial Diseases
Status: RECRUITING
Conditions: Mitochondrial Diseases
Interventions: DIETARY_SUPPLEMENT: hydroxytyrosol (HT) intake|DIETARY_SUPPLEMENT: hydroxytyrosol (HT) intake and withdraw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Infliximab Biosimilar in the Treatment of Resistant Hidradenitis Suppurativa
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: BIOLOGICAL: Infliximab-dyyb biosimilar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Links Between Motor Abilities and Language Ability Deficits in Patients With Post-stroke Aphasia
Status: RECRUITING
Conditions: Stroke|Aphasia
Interventions: OTHER: Syntactic comprehension battery (BCS)|OTHER: Montreal Cognitive Assessment (MOCA)|OTHER: Purdue Pegboard Test|OTHER: The Box and Block Test (BBT)|OTHER: Motor training with a tool|OTHER: Motor training with a hand|OTHER: on/off effect of tool motor training|OTHER: linguistic tasks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Examining the Feasibility of Prolonged Ketone Supplement Drink Consumption in Adults With Type 2 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes|Hyperglycemia|Ketosis
Interventions: DIETARY_SUPPLEMENT: D-β-hydroxybutyric acid with R-1,3-butanediol|OTHER: Inert placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: 4-Week Lead-In With Nitazoxanide Followed by 36 Weeks Nitazoxanide and Peginterferon Alfa-2a in Chronic Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Nitazoxanide|BIOLOGICAL: Peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chiropractic Treatment With Counseling Versus Counseling Alone for Promoting Smoking Cessation
Status: TERMINATED
Conditions: Smoking
Interventions: BEHAVIORAL: Counseling|PROCEDURE: Chiropractic adjustment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A DRF Study to Evaluate Safety, Tolerability, PK, and Activity of Oradoxel Monotherapy in Subjects w Adv. Malignancies
Status: UNKNOWN
Conditions: Solid Tumor
Interventions: DRUG: Oradoxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Creating Homestead Agriculture for Nutrition and Gender Equity (CHANGE) in Burkina Faso
Status: COMPLETED
Conditions: Anemia|Growth Retardation
Interventions: OTHER: Enhanced-Homestead Food Production Program (old)|BEHAVIORAL: WASH/malaria behavior change|DIETARY_SUPPLEMENT: LNS distribution|OTHER: Enhanced-Homestead Food Production Program (new)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study With MYL-1401H and Neulasta
Status: COMPLETED
Conditions: Breast Neoplasms|Chemotherapy-Induced Febrile Neutropenia
Interventions: BIOLOGICAL: MYL-1401H|BIOLOGICAL: Neulasta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Magnesium Sulphate Pre-exposure on Oxytocin-induced Contractility in Desensitized Human Myometrium - an in Vitro Study
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Oxytocin|DRUG: Magnesium Sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Volunteers Investigating How Quickly and to What Extent BAY1817080 is Taken up, Distributed, Broken Down and Eliminated From the Body, as Well as the Difference Between 2 Different Types of Tablets of BAY1817080 and the Difference Between Oral Dose and Dose in the Vein
Status: COMPLETED
Conditions: Biological Availability
Interventions: DRUG: BAY1817080 - Formulation A|DRUG: BAY1817080 - Formulation B|DRUG: [13C715N]-BAY 181708 stable isotope label (SIL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Therapeutic Effects of Peroneal Nerve Functional Electrical Stimulation for Lower Extremity in Patients With Sub-acute Post-stroke Hemiplegia
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: WA group|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Effectiveness of Shiatsu on Fatigue in Patients With Axial Spondyloarthritis
Status: RECRUITING
Conditions: Spondyloarthritis
Interventions: PROCEDURE: SHIATSU|PROCEDURE: DUMMY SHIATSU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Tailoring Of Platelet Inhibition to Avoid Stent Thrombosis
Status: COMPLETED
Conditions: Coronary Artery Disease|Myocardial Infarction|Stent Thrombosis|Heart Diseases|Acute Coronary Syndrome
Interventions: DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safety and Efficacy of Radio Frequency for the Treatment of Mild to Severe Inflammatory Acne
Status: RECRUITING
Conditions: Inflammatory Acne Vulgaris
Interventions: DEVICE: Morpheus8 Applicator Radiofrequency device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GEN2 Directed Cancer Immunotherapy Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma|Metastatic Cancer
Interventions: DRUG: GEN2 (HSV-Thymidine Kinase-m2 and hGM-CSF Genes)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy And Safety Of Tofacitinib In Psoriatic Arthritis: Comparator Study
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: Tofacitinib 5 mg BID|DRUG: Tofacitinib 10 mg BID|DRUG: Adalimumab|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Natural History and Muscle Fatigability of Patients With Congenital Myopathies.
Status: RECRUITING
Conditions: Central Core Disease|Multi-Minicore Disease|Nemaline Myopathy|Centronuclear Myopathy
Interventions: OTHER: Natural history and non therapeutical therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sirolimus and Gold Sodium Thiomalate in Treating Patients With Advanced Squamous Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Recurrent Non-small Cell Lung Cancer|Squamous Cell Lung Cancer|Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: sirolimus|DRUG: gold sodium thiomalate|OTHER: pharmacological study|GENETIC: RNA analysis|GENETIC: polymerase chain reaction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pharmacodynamics and Pharmacokinetics of Biphasic Insulin Aspart 30 and Insulin Glargine and Insulin Glulisine Therapy in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 30|DRUG: insulin glargine|DRUG: insulin glulisine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydrophobic Tubes for the Treament of Lower and Upper Limb Lymphedema
Status: NOT_YET_RECRUITING
Conditions: Lymphedema of Leg
Interventions: PROCEDURE: implantation of hydrophobic tubes for edema fluid drainage|DEVICE: Best Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Three Local Block Techniques for Diabetic Foot Surgery
Status: UNKNOWN
Conditions: Anesthesia, Regional
Interventions: PROCEDURE: sciatic nerve block|PROCEDURE: ankle block|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation and Diagnosis of the Chromosome Variation in Donated/Abandoned Blastocyst
Status: RECRUITING
Conditions: Chromosome Translocation|Genetic Disorders in Pregnancy|Recurrent Miscarriage
Interventions: DIAGNOSTIC_TEST: NGS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cohort Follow-up of Patients With Renal or Craniocervical Fibromuscular Dysplasia
Status: COMPLETED
Conditions: Fibromuscular Dysplasia
Interventions: OTHER: Abdominal and supra-aortic trunks vascular imaging|GENETIC: Blood sampling (genetic)|OTHER: Blood sampling (biomarkers)|OTHER: Urine sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Enteral Nutrition Supplemented With Prebiotics on Colonic Microbiota in the Critically Ill Patients
Status: UNKNOWN
Conditions: Diarrhoea
Interventions: DIETARY_SUPPLEMENT: Prebiotics-free enteral formula|DIETARY_SUPPLEMENT: Prebiotics containing enteral formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: This Study Tests Different Doses of BI 1015550 in Patients With Idiopathic Pulmonary Fibrosis (IPF). The Study Tests How BI 1015550 is Taken up by the Body and How Well it is Tolerated.
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: BI 1015550|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Baclofen for Treatment of Muscle Spasms in Patients With Cirrhosis: A Pilot Study
Status: COMPLETED
Conditions: Muscle Cramps|Cirrhosis
Interventions: DRUG: Baclofen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention in Recipients With Primary IgA Nephropathy of Recurrence After Kidney Transplantation: ATG-F Versus Basiliximab as Induction Immunosuppressive Treatment
Status: TERMINATED
Conditions: Glomerulonephritis|IgAN
Interventions: DRUG: ATG-F|DRUG: Simulect
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Neoadjuvant Chemotherapy (NAC) Alone or in Combination With Immunotherapy Vaccine PRGN-2009 in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal (Head and Neck) Cancer
Status: RECRUITING
Conditions: Squamous Cell Carcinoma of the Head and Neck|Oropharynx|Human Papillomavirus Viruses|Drug Therapy|Cancer Vaccine
Interventions: DRUG: Docetaxel|DRUG: Cisplatin|DRUG: PRGN-2009
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Multi-Intervention Trial to Inhibit Precancerous Gastric Lesions in Lingu, Shandong Province
Status: COMPLETED
Conditions: Precancerous Gastric Lesions
Interventions: DRUG: Amoxicillin/omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vitamin D and Carboxy PTH Fragments in Coronary Calcification
Status: WITHDRAWN
Conditions: Coronary Calcification|Endstage Renal Disease|Parathyroid Hormone
Interventions: DRUG: Doxercalciferol administration|DRUG: Doxercalciferol administered by 1-84-7-84
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Digital Knee Osteoarthritis Mindset Intervention
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BEHAVIORAL: Mindset intervention|OTHER: Active comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Theory-based Health Behaviour Change Intervention in Patients of Metabolic Syndrome With Chronic Kidney Disease
Status: NOT_YET_RECRUITING
Conditions: Chronic Kidney Diseases|Metabolic Syndrome
Interventions: BEHAVIORAL: Theory-based health behaviour change interventio
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of the GLP-1 Analogue Exenatide on Type 2 Diabetes in CNS and Heart During Hyperglycemia Assessed by PET
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Byetta, Exenatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pembrolizumab Plus Amurubicin in Patients With Refractory Small-cell Lung Cancer
Status: UNKNOWN
Conditions: Small Cell Lung Cancer Extensive Stage
Interventions: DRUG: Pembrolizumab plus amurubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stability of Angle Fracture Fixation With (K) Shaped Titanium Miniplates Versus Two Miniplates
Status: UNKNOWN
Conditions: Mandible Fracture
Interventions: PROCEDURE: fixation of angle fracture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of AS1409 in Patients With Either Metastatic Renal Cell Carcinoma or Metastatic Malignant Melanoma
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma|Metastatic Malignant Melanoma
Interventions: DRUG: AS1409
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of XP12B in Women With Menorrhagia
Status: COMPLETED
Conditions: Menorrhagia|Heavy Menstrual Bleeding
Interventions: DRUG: Tranexamic acid tablets (XP12B)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Efficacy and Safety of CaReSR-1S to Repair Cartilage Defects of the Knee
Status: UNKNOWN
Conditions: Cartilage Defects
Interventions: DEVICE: CaReSR-1S|DEVICE: Microfracture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Steroids for Corneal Ulcers Trial
Status: COMPLETED
Conditions: Corneal Ulcer|Eye Infections, Bacterial
Interventions: DRUG: Antibiotics|DRUG: Topical corticosteroid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Clinical Study on the Safety and Efficacy of CAR-T in the Treatment of Relapsed / Refractory Non Hodgkin's Lymphoma
Status: RECRUITING
Conditions: Non-hodgkin's Lymphoma
Interventions: BIOLOGICAL: Auto CAR-T|DRUG: Cyclophosphamide,Fludarabine|PROCEDURE: Leukapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Severe Left Diaphragmatic Hernia (CDH)
Status: RECRUITING
Conditions: Congenital Diaphragmatic Hernia
Interventions: DEVICE: 11540KE and Balt Goldbal 2 balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Multimodal Intervention on Function in Older Frail People With Diabetes in Latinamerican
Status: ACTIVE_NOT_RECRUITING
Conditions: Frailty Syndrome|Frail Elderly Syndrome|Diabetes Mellitus, Type 2
Interventions: OTHER: Multimodal intervention|OTHER: Usual care group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Group Prenatal Care Intervention to Address Maternal and Child Non-Communicable Disease (NCD) Risk in American Samoa
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Group Prenatal Care (GPNC)|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pandemic Influenza A (H1N1)Candidate Vaccines
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: pandemic vaccine 1|BIOLOGICAL: pandemic vaccine 2|BIOLOGICAL: pandemic vaccine 5|BIOLOGICAL: pandemic vaccine 6|BIOLOGICAL: pandemic vaccine 9|BIOLOGICAL: pandemic vaccine 10|BIOLOGICAL: pandmeic vaccine 11|BIOLOGICAL: pandmeic vaccine 12|BIOLOGICAL: pandmic vaccine 13|BIOLOGICAL: placebo group 14
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Effect on Glucose Control and Safety of AC2993 in Patients With Type 2 Diabetes Treated With Metformin, Sulfonylurea, or Metformin and Sulfonylurea Combination
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: AC2993
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Terlipressin for Refractory Septic Shock
Status: RECRUITING
Conditions: Septic Shock|Refractory Shock|Norepinephrine Adverse Reaction
Interventions: DRUG: Terlipressin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Study: Ligasure Versus Conventional Hemorrhoidectomy in III and IV Degree Hemorrhoids.
Status: COMPLETED
Conditions: Hemorrhoidectomy|Hemorrhoids Third Degree|Hemorrhoids Fourth Degree|Operative Time|Pain, Postoperative|Wound Healing|Return to Work
Interventions: PROCEDURE: Hemorrhoidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Multiple Doses of MT-8554 in Female Subjects Experiencing Vasomotor Symptoms
Status: COMPLETED
Conditions: Vasomotor Symptoms
Interventions: DRUG: MT-8554 low dose|DRUG: MT-8554 middle dose|DRUG: MT-8554 high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Registry For Children, Adolescents And Adults With Osteosarcoma And Biologically Related Bone Sarcomas
Status: NOT_YET_RECRUITING
Conditions: Osteosarcoma|Bone Tumor|Bone Sarcoma|High Grade Sarcoma|Osteoblastic Osteosarcoma|Chondroblastic Osteosarcoma|Fibroblastic Osteosarcoma|Conventional Osteosarcoma|Conventional Central Osteosarcoma of Bone|Low Grade Central Osteosarcoma|Osseous Sarcoma|Osseous Tumor|Small Cell Osteosarcoma|Telangiectatic Osteosarcoma|Undifferentiated Pleomorphic Sarcoma|Parosteal Osteosarcoma|Periosteal Osteosarcoma|Extraskeletal Osteosarcoma|Recurrent Osteosarcoma|High Grade Surface Osteosarcoma|Osseous Angiosarcoma|Osseous Fibrosarcoma|Osseous Leiomyosarcoma|Osseous Dedifferentiated Chondrosarcoma|Osseous Mesenchymal Chondrosarcoma|Clear Cell Osteosarcoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate Benefits & Safety of Endourage Formula C™ Oral Drops in People With Post-Acute COVID-19 Syndrome.
Status: COMPLETED
Conditions: Covid 19
Interventions: DIETARY_SUPPLEMENT: Targeted Wellness Formula C™ Sublingual Drops - 1200mg - 30 mL (Formula C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Irbesartan and Atenolol in Hypertensive Heart Disease
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Irbesartan|DRUG: Atenolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MagnetOs Flex Matrix Compared to Cell Based Allografts in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion
Status: NOT_YET_RECRUITING
Conditions: Degenerative Disc Disease|Spine Fusion|Leg Pain and/or Back Pain
Interventions: DEVICE: MagnetOs Flex Matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Semi-replicate Crossover Bioequivalence Study of Dirithromycin of (Abdi İbrahim İlaç San. Ve Tic. A. Ş., Turkey) in Healthy Subjects Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DIRITHROMYCIN 500 MG ENTERIC COATED TABLET|DRUG: DYNABAC 250 MG ENTERIC COATED TABLET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of Monovalent Type 2 Oral Poliovirus Vaccine
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: mOPV2 at 6 and 7 weeks of age|BIOLOGICAL: mOPV2 at 6 and 8 weeks of age|BIOLOGICAL: mOPV2 at 6 and 10 weeks of age|BIOLOGICAL: IPV at 6 weeks of age
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: UARK 2005-05, Coagulation-Related Effects of Velcade Treatment in Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: MULTIPLE MYELOMA
Interventions: DRUG: Velcade
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Perspective Study of the Antiviral Efficacy and Safety of Switching to TAF Treatment in CHB Adults With Suboptimal Response (SOR) and Intolerant to Entecavir
Status: UNKNOWN
Conditions: HBV
Interventions: DRUG: Tenofovir Alafenamide (TAF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias
Status: ACTIVE_NOT_RECRUITING
Conditions: Congenital Hemolytic Anemia|Sickle Cell Disease
Interventions: PROCEDURE: Peripheral blood hematopoietic progenitor cell (PBPC) transplant|DRUG: Alemtuzumab|PROCEDURE: Peripheral blood hematopoietic progenitor cell Apheresis|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Usefulness of Ultrasound Guided Technique Insertion of Radial Artery Catheter in Neonates and Infants
Status: COMPLETED
Conditions: Catheterization, Peripheral
Interventions: PROCEDURE: Radial arterial cannulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effect of Benzydamine Hydrochloride to Postoperative Sore Throat in Pediatric Patients
Status: COMPLETED
Conditions: Intubation Complication
Interventions: DRUG: Benzydamine Hydrochloride|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Topo-pachimetric Accelerated Epi-On Cross-linking Compared to Dresden Protocol Using Riboflavin With Vitamin E TPGS
Status: COMPLETED
Conditions: Keratoconus
Interventions: OTHER: accelerated custom-fast CXL|OTHER: Standard CXL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy and Safety of Ezetimibe or Statin Monotherapy to Co-Administration of Both
Status: COMPLETED
Conditions: Cholesterol, LDL
Interventions: DRUG: Ezetimibe and Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Airflow in the Lungs Using Helium MRI
Status: ACTIVE_NOT_RECRUITING
Conditions: COPD|Healthy|Constrictive Bronchitis
Interventions: DRUG: hyperpolarized helium MRI of the chest
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of 3 Techniques for Ultrasound-guided Femoral Nerve Catheter Insertion
Status: COMPLETED
Conditions: Total Knee Replacement Surgery
Interventions: PROCEDURE: ultrasound guidance alone|PROCEDURE: ultrasound guidance and needle stimulation|PROCEDURE: ultrasound guidance and catheter stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Stem Cell Therapy for Type 1 Diabetes Mellitus
Status: UNKNOWN
Conditions: Type 1 Diabetes Mellitus
Interventions: BIOLOGICAL: autologous bone marrow mononuclear cells and umbilical cord mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trancutaneous Abdominal Stimulation on Bowel Function.
Status: UNKNOWN
Conditions: Spinal Cord Injuries|Constipation
Interventions: DEVICE: Non-invasive, surface electrical stimulation device, DS5 Digitimer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Study of Revlimid®, Velcade® Dexamethasone and Doxil® (RVDD)for Newly Diagnosed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: Bortezomib|DRUG: Dexamethasone|DRUG: Doxil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Dysfunction in Traumatic Brain Injury
Status: COMPLETED
Conditions: Trauma, Head|Cardiac Complication
Interventions: DIAGNOSTIC_TEST: Electrocardiogram|DIAGNOSTIC_TEST: Transthoracic Echocardiogram|DIAGNOSTIC_TEST: Cardiac enzyme - Troponin I Levels
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p