pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Double Blind Placebo Controlled Study of Outpatient Intravenous Ketamine for the Treatment of CRPS
Status: COMPLETED
Conditions: Complex Regional Pain Syndrome
Interventions: DRUG: Ketamine|OTHER: IV NSS|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Recombinant Interleukin 21 in Combination With Sorafenib for Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: rIL-21 only|DRUG: rIL-21 + sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Roaccutane on Ca, P, PTH and Vitamin D Metabolites in the Treatment of Sever Acne
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: isotretinoin (Roaccutane)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment for Insomnia During Pregnancy
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: BEHAVIORAL: Arousal Based Therapy for Insomnia|BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TEAM-Project: Trial on the Effect of Anesthetics on Morbidity and Mortality
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Inhalational anesthetic|DRUG: Intravenous anesthetic, propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Safety, Pharmacokinetics and Efficacy of EDO-S101, in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Small-cell Lung Cancer|Soft Tissue Sarcoma|Triple-negative Breast Cancer|Ovarian Cancer|Endometrial Cancer
Interventions: DRUG: Tinostamustine (EDO-S101)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of 60-minute Versus 90-minute Sessions in Treating PTSD Using Prolonged Exposure
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|PTSD
Interventions: BEHAVIORAL: Prolonged Exposure Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 24-hour Lung Function in Subjects With Moderate to Very Severe COPD After Treatment With PT003 and Placebo MDI
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: GFF MDI (PT003)|DRUG: Placebo MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Tolerability of Switching Subjects on Chronic ATC Opioid Therapy to Buprenorphine HCl Buccal Film
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Buprenorphine|DRUG: Placebo film|DRUG: Oxycodone|DRUG: Morphine sulfate|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of Autologous Serum Eye-drops as Tears in Patients With Recalcitrant Dry Eye
Status: COMPLETED
Conditions: Xerophthalmia
Interventions: DRUG: Autologous serum eyedrops
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Baclofen for the Treatment of Cocaine Dependence - 1
Status: COMPLETED
Conditions: Cocaine-Related Disorders
Interventions: DRUG: Baclofen|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy
Status: RECRUITING
Conditions: Obstructive Sleep Apnea of Adult|Preeclampsia|Obstetrical Complications
Interventions: DEVICE: Continuous Positive Airway Pressure|OTHER: Sleep Advice Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Success of Prophylactic Enteral Nutrition in Therapeutic Intensification With Autograft of Autologous Hematopoietic Cells in Hematology
Status: COMPLETED
Conditions: Lymphoma|Myeloma
Interventions: DIETARY_SUPPLEMENT: Enteral Nutrition
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact of Air Travel on Passenger Cognitive Functions
Status: UNKNOWN
Conditions: Air Travel
Interventions: DRUG: Citicoline|DRUG: Cytochrome C6|DRUG: Sodium Chloride Oral Product|DRUG: Potassium Chloride Oral Product|DRUG: Sodium Citrate Oral Product|DRUG: Dextrose Oral Tablet, Chewable|DRUG: Domperidone Oral Product|DRUG: Simethicone|DRUG: Acetylsalicylic acid|DRUG: Magnesium hydroxide|DRUG: Probiotic Formula|DRUG: Melatonin 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ovarian Endometrioma Ablation Using Plasma Energy Versus Cystectomy
Status: UNKNOWN
Conditions: Ovarian Endometrioma
Interventions: PROCEDURE: Ablation using the PlasmaJet system|PROCEDURE: Cystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topiramate to Reduce Heavy Drinking in HIV-Positive Heavy Drinkers
Status: TERMINATED
Conditions: Heavy Drinking|HIV|Alcohol Dependence
Interventions: DRUG: Topiramate|BEHAVIORAL: Medical Management|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Glucose Monitor Use in Pregnancy
Status: RECRUITING
Conditions: Type 2 Diabetes Treated With Insulin|Pregnancy, High Risk
Interventions: DEVICE: Continuous Glucose Monitor|DEVICE: Routine Capillary Blood Glucose Monitoring (Fingerstick Glucose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: GENe EXpression After Regional or General ANesthesia in Patients Undergoing Breast Cancer Surgery
Status: UNKNOWN
Conditions: Breast Cancer Female
Interventions: PROCEDURE: General anesthesia|PROCEDURE: Regional anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Exploratory, Double-Blind, Placebo-Controlled Study of the Medical Food Vayarin in Children With Autism Spectrum Disorder (ASD)
Status: COMPLETED
Conditions: Autistic Disorder
Interventions: OTHER: Medical Food : Vayarin_005|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Role of Lung Ultrasound in Confirmation of Correct Double Lumen Endotracheal Tube Placement in Thoracic Surgeries
Status: COMPLETED
Conditions: Diagnostic Accuracy
Interventions: DIAGNOSTIC_TEST: Lung auscultation|DEVICE: Fiberoptic bronchoscopy|DEVICE: Lung Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Aolanti Weikang Tablets in Healthy Volunteers
Status: COMPLETED
Conditions: Functional Dyspepsia
Interventions: DRUG: Aolanti Weikang tablets|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy, Bone Marrow Transplantation, and Radiation Therapy in Treating Infants With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: filgrastim|DRUG: asparaginase|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: dexamethasone|DRUG: etoposide|DRUG: leucovorin calcium|DRUG: mercaptopurine|DRUG: mesna|DRUG: methotrexate|DRUG: methylprednisolone|DRUG: pegaspargase|DRUG: prednisone|DRUG: therapeutic hydrocortisone|DRUG: vincristine sulfate|PROCEDURE: allogeneic bone marrow transplantation|RADIATION: low-LET cobalt-60 gamma ray therapy|RADIATION: low-LET photon therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of the Japanese Encephalitis Vaccine IC51
Status: COMPLETED
Conditions: Japanese Encephalitis
Interventions: BIOLOGICAL: Japanese Encephalitis purified inactivated vaccine (IC51)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Amway Uric Acid Lowering Product on Hyperuricemia
Status: RECRUITING
Conditions: Hyperuricemia
Interventions: DIETARY_SUPPLEMENT: Study Product A (High-dose 2X)|DIETARY_SUPPLEMENT: Study Product B (Low-dose X)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of LY3471851 in Adults With Systemic Lupus Erythematosus (SLE)
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: LY3471851|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Effect-site Concentration of Remifentanil for Preventing Cough Against Endotracheal Tube During Anesthetic Emergence According to Anesthetics (Sevoflurane, Desflurane, and Propofol)
Status: COMPLETED
Conditions: Female Patients Undergoing Thyroidectomy
Interventions: DRUG: up-and-down method to find out effective concentration of remifentanil for preventing cough
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effects of an Intermittent Reduced Calorie Diet on Crohn's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammatory Bowel Diseases|Crohn Disease|Diet Modification
Interventions: OTHER: Intermittent Reduced Calorie Diet (IRCD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Effects of Korean Adapted APD in Automated Peritoneal Dialysis Patients
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic
Interventions: PROCEDURE: KAPD-C|PROCEDURE: KAPD-A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of IW-1973 on the Exercise Capacity of Patients With Heart Failure With Preserved Ejection Fraction (HFpEF)
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: IW-1973|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endodontic Treatment of Primary Teeth With Guedes-Pinto Paste Without Antibiotic
Status: COMPLETED
Conditions: Pulp Disorder
Interventions: DRUG: Endodontic treatment using Guedes-Pinto Paste|DRUG: Endodontic using Guedes-Pinto Paste without antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: WES of NF2-associated in Comparison to Sporadic Vestibular Schwannomas - Correlation With Clinical Data
Status: COMPLETED
Conditions: Neurofibromatosis Type 2|Vestibular Schwannoma|Acoustic Neuroma
Interventions: DIAGNOSTIC_TEST: Whole exome sequencing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Amniotic Fluid Sludge in Cerclage Patients as an Indicator for Increased Risk of Preterm Delivery and Neonatal Outcome.
Status: COMPLETED
Conditions: High Risk Pregnancy|Incompetent Cervix|Cerclage|Amniotic Fluid Sludge|Gestation Age at Delivery.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pemetrexed and Cisplatin Treatment Before Surgery in Non Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-Small-Cell Lung Cancer
Interventions: DRUG: pemetrexed|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib With Concurrent Brain Radiotherapy and Secondary Brain Radiotherapy After Recurrence With Erlotinib in NSCLC Non-increased-intracranial-pressure Symptomatic Brain Metastases
Status: UNKNOWN
Conditions: Non-small-cell Lung Cancer|Brain Metastases
Interventions: DRUG: Erlotinib|RADIATION: concurrent brain radiotherapy|RADIATION: secondary brain radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: As Study of the Pharmacokinetics of Paliperidone Extended-release and Risperidone Immediate-release Formulations
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Paliperidone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of GHX02 in the Treatment of Acute Bronchitis
Status: UNKNOWN
Conditions: Acute Bronchitis
Interventions: DRUG: GHX02|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Clinical Effect of Daily Next Science™ Acne Gel (NAG) on Mild to Moderate Facial Acne
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Next Science Acne Gel|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Tafamidis on Transthyretin Stabilization, Safety, Tolerability and Efficacy in Transthyretin Amyloid Polyneuropathy Patients
Status: UNKNOWN
Conditions: Transthyretin Amyloidosis
Interventions: DRUG: Tafamidis Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability and Pharmacokinetics of Single Ascending Oral Doses of J147
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: J147|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: INCB106385 Alone or in Combination With Immunotherapy in Advanced Solid Tumors
Status: COMPLETED
Conditions: Ovarian Cancer|Bladder Cancer|Non Small Cell Lung Cancer|Squamous Cell Carcinoma of Head and Neck|Triple Negative Breast Cancer|Castration Resistant Prostate Cancer|Colorectal Cancer|Gastric/ Gastroesophageal Junction|Hepatocellular Carcinoma|Pancreatic Ductal Adenocarcinoma|Squamous Carcinoma of the Anal Canal
Interventions: DRUG: INCB106385|DRUG: INCMGA00012
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasotracheal Intubation in Critically Ill.
Status: RECRUITING
Conditions: Tracheal Intubation Morbidity|Critical Care
Interventions: DEVICE: nasotracheal intubation|DEVICE: orotracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of 2 Formulations of an Intramuscular A/H5N1 Pandemic Influenza Vaccine in Children
Status: COMPLETED
Conditions: Influenza|Orthomyxoviridae Infections|Influenza A Virus Infection
Interventions: BIOLOGICAL: A/H5N1 Inactivated, split-virion pandemic influenza vaccine|BIOLOGICAL: A/H5N1 Inactivated, split virion pandemic influenza vaccine|BIOLOGICAL: A/H5N1 Inactivated, split virion pandemic influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Peri-Operative Morbidity and Quality of Life After Coronary Artery Bypass Graft (CABG)
Status: COMPLETED
Conditions: Coronary Artery Bypass Graft Surgery
Interventions: PROCEDURE: Regulating Mean Arterial Pressure during cardiopulmonary bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Safety and Immunogenicity of SCTV01C in Healthy Population Aged ≥18 Years Previously Vaccinated With Inactivated COVID-19 Vaccine.
Status: UNKNOWN
Conditions: COVID-19|SARS-CoV-2 Infection
Interventions: BIOLOGICAL: SCTV01C|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prazosin for Alcohol Use Disorder With Withdrawal Symptoms
Status: RECRUITING
Conditions: Alcohol Withdrawal
Interventions: DRUG: Prazosin|BEHAVIORAL: 12-Step Facilitation with Relapse Prevention and Contingency Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Evacetrapib (LY2484595) in Participants With Hepatic (Liver) Impairment
Status: COMPLETED
Conditions: Hepatic Insufficiency
Interventions: DRUG: Evacetrapib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Intralipid Infusion in Patients With Recurrent Implantation Failure
Status: UNKNOWN
Conditions: Subfertility
Interventions: DRUG: Intralipid 20%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: European Association of Cardiovascular Imaging Multiple and Mixed Valvular Disease Study
Status: RECRUITING
Conditions: Heart Valve Diseases|Multiple Valve Disease, Unspecified|Aortic Valve Disease|Aortic Valve Stenosis|Aortic Valve Insufficiency|Mitral Valve Disease|Mitral Valve Stenosis|Mitral Valve Insufficiency and Aortic Valve Insufficiency|Mitral Valve Insufficiency|Aortic Valve Stenosis With Insufficiency|Mitral Valve Disease Mixed|Tricuspid Valve Insufficiency|Tricuspid Valve Disease|Tricuspid Stenosis
Interventions: OTHER: Intervention not provided
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Nebulization Positions in Asthmatic Children
Status: COMPLETED
Conditions: Asthma Attack|Asthma in Children|Asthma Acute|Asthma
Interventions: OTHER: A Randomized Controlled Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Initiating Early Control of Migraine Pain and Associated Symptoms
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: AXS-07 (MoSEIC meloxicam and rizatriptan)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Clinical Usefulness of [F-18]Florastamin PET/CT Imaging Diagnosis Compared to MRI Diagnosis
Status: RECRUITING
Conditions: High Risk Prostate Carcinoma
Interventions: DRUG: [F-18]Florastamin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety Study of UT-15C SR (Oral Treprostinil) in Patients Undergoing a Lower Limb Endovascular Procedure
Status: COMPLETED
Conditions: Critical Limb Ischemia
Interventions: DRUG: treprostinil dienthanolmine sustained release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Food on Pharmacokinetics of MY008211A Tablets in Healthy Adult Subjects
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: MY008211A tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RaGuS Trial by Postoperative Patients
Status: UNKNOWN
Conditions: Vasoplegic Syndrome|Sirs Due to Noninfectious Process Without Organ Dysfunction|Orthostatic Hypotension
Interventions: DRUG: Midodrine Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PENG Block for Traumatic Hip Fracture in the Emergency Department
Status: COMPLETED
Conditions: Hip Fractures|Acute Pain|Emergency Department
Interventions: PROCEDURE: Ultrasound-guided Pericapsular Nerve Group (PENG) Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Prandial High Resolution Impedance- Manometry
Status: COMPLETED
Conditions: Gastro-esophageal Reflux
Interventions: OTHER: Correlating the number of reflux episodes detected on 1-h post prandial esophageal high resolution manometry combined and those detected on ambulatory 24-h pH-impedance monitoring performed on PPI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Ascorbic Acid and Grape Seed Extract in Oxidative Stress Induced by on Pump Heart Surgery
Status: UNKNOWN
Conditions: CABG-Induced Oxidative Stress
Interventions: DRUG: GSE|DRUG: Vit C (Ascorbic Acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Washed Microbiota Transplantation for Chronic Constipation in Adults
Status: RECRUITING
Conditions: Constipation
Interventions: DRUG: High-dose washed microbiota suspension|DRUG: Low-dose washed microbiota suspension|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose Laxative Improves Performance and Feasibility of Computed Tomography Colonography (CTC)
Status: COMPLETED
Conditions: Gastrointestinal Complication
Interventions: DRUG: Bisacodyl & PEG-CS|DRUG: Iopamidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examining the Impact of Sirolimus on Ketamine's Antidepressant Effects
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Ketamine|DRUG: sirolimus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Health and Nutrition Survey on Shenzhen Children
Status: COMPLETED
Conditions: Nutrition Disorder, Child|Nutrition Disorders in Adolescence|Nutritional Deficiency|Nutrition, Healthy|Nutritional Stunting|Nutritional and Metabolic Diseases|Nutritional Imbalance|Development, Child|Development, Adolescent|Growth Disorders|Growth; Stunting, Nutritional
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Controlled Double Blind Trial of Short vs Long Acting Dihydrocodeine in Chronic Non-malignant Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Dihydrocodeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Psychosocial Benefits of Gratitude Journals
Status: COMPLETED
Conditions: Happiness
Interventions: BEHAVIORAL: Reflective Interpersonal Gratitude|BEHAVIORAL: Reflective-Behavioral Gratitude|BEHAVIORAL: Neutral Control Journal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Magnesium on the Recovery Time of Neuromuscular Blockade With Sugammadex
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: DRUG: Magnesium Sulfate|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Albumin Interferon Alfa-2b With Ribavirin Compared to Peg-IFN Alfa-2a With Ribavirin in IFN Naive Patients Geno2/3
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: albumin interferon alfa-2b|DRUG: peginterferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Undiagnosed Diabetes in a Dental Setting
Status: COMPLETED
Conditions: Prediabetic State|Type 2 Diabetes Mellitus With Oral Complications|Periodontal Pocket|Tooth Loss
Interventions: BEHAVIORAL: Enhanced intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safety, Pharmacokinetics and Efficacy of KBSA301 in Severe Pneumonia (S. Aureus)
Status: COMPLETED
Conditions: Pneumonia Due to Staphylococcus Aureus
Interventions: DRUG: KBSA301|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Postrhinoplasty Taping on Postoperative Edema and Nasal Draping
Status: COMPLETED
Conditions: Nasal Deformity|Edema|Rhinoplasty
Interventions: PROCEDURE: Postrhinoplasty taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial to Compare Efficacy and Safety of CRT VS Neo-CRT in Patients Who Achieved CCR for Esophageal Cancer
Status: UNKNOWN
Conditions: Stage II Esophageal Cancer|Stage III Esophageal Cancer
Interventions: RADIATION: Definitive Radiochemotherapy|PROCEDURE: Neoadjuvant Radiochemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tacrolimus and Mycophenolate Mofetil (MMF) in GVHD Prophylactic Regimen Compared to Tacrolimus and Methotrexate (MTX
Status: COMPLETED
Conditions: Mucositis|Graft-versus-host Disease
Interventions: DRUG: Tac+MTX|DRUG: TAC + MMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimalization of Nephroprotection Using Agents Inhibiting Renin-Angiotensin-Aldosterone System
Status: COMPLETED
Conditions: Chronic Kidney Disease|Proteinuria
Interventions: DRUG: Spironolactone (Spironol) 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Clinical Study of CD3-CD20 Bisspecific Antibody Based Therapy Combined With CD19-CAR T Cells in the Treatment of Relapsed Refractory B-cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: B-cell Non-Hodgkin Lymphoma
Interventions: DRUG: Bispecific antibody-based combined with CAR-T cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VenaSeal Sapheon Closure System Pivotal Study (VeClose)
Status: COMPLETED
Conditions: Great Saphenous Vein (GSV) With Venous Reflux Disease
Interventions: DEVICE: VenaSeal SCS|DEVICE: ClosureFast Radiofrequency Ablation (RFA)|DEVICE: Roll-in (VenaSeal SCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Therapeutics and Endothelial Dysfunction in T1DM Patients
Status: COMPLETED
Conditions: Endothelial Dysfunction|Diabetes Mellitus, Type 1|Biomarkers|Endothelial Progenitor Cells|SGLT 2 Inhibitors|Incretins|Glucose Excursions|FMD|FPF|Arterial Stiffness
Interventions: DRUG: Semaglutide Pen Injector [Ozempic]|DRUG: Empagliflozin 10 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: One Year Clinical Performance of Self Adhesive Giomer Containing Flowable Composite in Restoring Class V Cavities
Status: UNKNOWN
Conditions: Class V Dental Caries|Composite Resin and Self Adhesive Flowable Composite
Interventions: OTHER: (FIT SA F03, SHOFU, USA)|OTHER: (Neo Spectra™ ST, Dentsply, Sirona, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REgiStry-based Cardiovascular qUality improvEment Research
Status: RECRUITING
Conditions: Percutaneous Coronary Intervention|Heart Failure|Cardiometabolic Syndrome|Structural Heart Abnormality
Interventions: BEHAVIORAL: Cardiac rehabilitation|OTHER: Active post-market surveillance of devices|OTHER: Multi-omics approach to precision medicine|OTHER: The prescription pattern analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis in the Treatment of Thoracoabdominal and Pararenal Aortic Aneurysms
Status: RECRUITING
Conditions: Thoracoabdominal Aortic Aneurysm
Interventions: DEVICE: GORE EXCLUDER Thoracoabdominal Branch Endoprosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Daily Intake of 0.5 L of Water Saturated With Molecular Hydrogen for 21 Days in COVID-19 Patients Treated in Ambulatory Care
Status: UNKNOWN
Conditions: SARS-CoV-2|Covid19|AMBULATORY CARE
Interventions: DIETARY_SUPPLEMENT: MOLECULAR HYDROGEN|DIETARY_SUPPLEMENT: PLACEBO MAGNESIUM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Very Low Nicotine Content Cigarettes in a Complex Marketplace
Status: COMPLETED
Conditions: Tobacco Smoking|Nicotine Dependence
Interventions: DRUG: Very Low Nicotine Content Cigarettes|DRUG: Normal Nicotine Content Cigarettes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effectiveness of Nasal Corticosteroids Versus Placebo in Nasal Obstruction in Patients With Nasal Septal Deviation
Status: COMPLETED
Conditions: Nasal Obstruction
Interventions: DRUG: Triamcinolone Acetonide|DRUG: Ayr saline nasal mist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maternal Haemodynamic Changes After Crystalloid Co-loading and Phenylephrine Versus Phenylephrine Alone During Spinal Anaesthesia for Elective Caesarean Delivery
Status: COMPLETED
Conditions: Maternal Haemodynamic Stability
Interventions: DRUG: Phenylephrine infusion|DRUG: Phenylephrine infusion and Ringer-Acetate bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Can a Novel Manual Therapy Technique Help Relieve Stress? Assessing Effects of Primal Reflex Release on the Body's Stress Response
Status: NOT_YET_RECRUITING
Conditions: Psychological Stress
Interventions: OTHER: Primal Reflex Release Technique (PRRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bunionectomy Trial With GRT6005
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: GRT6005|DRUG: Morphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancement of the Haemostatic Effect of Platelets in the Presence of High Normal Concentrations of Von Willebrand Factor
Status: RECRUITING
Conditions: Bleeding
Interventions: DRUG: Wilate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose Pharmacokinetics and Pharmacodynamics of Bupivacaine Following Transversus Abdominis Plane (TAP) Block in Neonates
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Validation of a Test System for Development of Medications for Alcoholism
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: Naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Opioid and Duloxetine for Postoperative Pain Control After Total Knee Arthroplasty: RCT
Status: UNKNOWN
Conditions: Total Knee Arthroplasty|Osteoarthritis, Knee
Interventions: DRUG: Duloxetine vs. Opioid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Dry Needling on Patients With Knee Pain
Status: RECRUITING
Conditions: Patellofemoral Pain Syndrome|Anterior Knee Pain Syndrome
Interventions: PROCEDURE: Dry Needling|PROCEDURE: Sham Dry Needling|OTHER: Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neural and Immune Correlates of CIPN and Possible Analgesic Effect of Non-invasive Motor Cortex Stimulation
Status: NOT_YET_RECRUITING
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: DEVICE: transcranial direct current stimulation Soterix REMOTE 1x1 miniCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Influence of the Brownie Breast Shield on the Dynamics of Milk Removal
Status: COMPLETED
Conditions: Lactation
Interventions: DEVICE: PersonalFit - Breast shield|DEVICE: Brownie - Breast shield
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Efficiency of Ultrasound-Guided Lavage and Subacromial Bursa Injection in Calcific Tendinitis
Status: COMPLETED
Conditions: Calcific Tendinitis|Calcific Tendinitis of Shoulder|Shoulder Pain
Interventions: PROCEDURE: Ultrasound Guided Lavage|PROCEDURE: Ultrasound Guided Subacromial Bursa Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Targeting Sympathetic Overactivity in Heart Failure Patients With Statins
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Performance of Two Different Restorative Materials in Restoring Class II Cavities of Primary Molars
Status: RECRUITING
Conditions: Dental Caries Class II
Interventions: PROCEDURE: restoration of proximal cavities of primary molars with flowable giomer|PROCEDURE: restoration of proximal cavities of primary molars with highly viscous glass ionomer cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Estrogen and Platelet Rich Plasma in Treatment of Atrophic Vaginitis
Status: RECRUITING
Conditions: Atrophic Vaginitis|Postmenopausal Atrophic Vaginitis
Interventions: DRUG: Conjugated Estrogens vaginal cream 0,625mg|COMBINATION_PRODUCT: platelet rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Combination Clindamycin Phosphate/Tretinoin Gel Alone Versus With Benzoyl Peroxide Foaming Cloths for Facial Acne
Status: UNKNOWN
Conditions: Acne Vulgaris
Interventions: DRUG: clindamycin phosphate 1.2%/tretinoin 0.025% gel alone|DRUG: clindamycin phosphate 1.2%/tretinoin 0.025% gel plus benzoyl peroxide 6% foaming cloths
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Mometasone Nasal Spray, Nasonex Nasal Spray, Nasonex Nasal Spray Suspension, & Placebo for Treatment of Seasonal Allergies for Safety, Efficacy, & Superiority in 1520 Male & Female Volunteers
Status: COMPLETED
Conditions: Treatment of the Signs and Symptoms of Seasonal Allergic Rhinitis
Interventions: DRUG: Mometasone Furoate Monohydrate Nasal Spray, 50 μg/act.|DRUG: Nasonex® Nasal Spray, 50 μg/actuation|DRUG: Nasonex® Nasal Spray Suspnsn, 50 μg/actuation|DRUG: Placebo Nasal Spray, 50 μL/actuation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DTaP-IPV/Hib Vaccine Primary & Booster Vaccinations Versus Co-administration of DTaP-IPV and Hib Vaccine in Japanese Infants
Status: COMPLETED
Conditions: Tetanus|Diphtheria|Pertussis|Poliomyelitis|Bacterial Meningitis
Interventions: BIOLOGICAL: DTaP-IPV/Hib Combined vaccine|BIOLOGICAL: DTaP-IPV vaccine and Hib vaccine|BIOLOGICAL: DTaP-IPV/Hib Combined vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: High-Dose Vitamin D Induction in Optic Neuritis
Status: TERMINATED
Conditions: Optic Neuritis
Interventions: DRUG: Vitamin D3|DRUG: Placebo/Standard of Care Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self-Management Interventions After an ICD Shock
Status: NOT_YET_RECRUITING
Conditions: Implantable Defibrillator User|Stress Reaction|Ptsd|Stress Management|Social Cognitive Theory
Interventions: BEHAVIORAL: Self-Paced Self-Management (SPSM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effect of Multiple Doses of Tradipitant on CYP3A4 Using Midazolam as a Substrate in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: tradipitant|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Applying Wolbachia to Eliminate Dengue
Status: TERMINATED
Conditions: Dengue|Zika Virus Infection|Chikungunya Fever
Interventions: BIOLOGICAL: Wolbachia-infected Aedes aegypti mosquitoes|OTHER: standard practice dengue control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Puerto Rico Cuidalos Parent-adolescent Program
Status: COMPLETED
Conditions: HIV/AIDS and Infections|Sexually Transmitted Diseases|Pregnancy Prevention
Interventions: BEHAVIORAL: Parental Communication intervention|BEHAVIORAL: Health promotion control condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Study in Healthy Volunteers of a New Paediatric Formulation of Valacyclovir
Status: COMPLETED
Conditions: Varicella Zoster Virus Infection|Herpes Simplex Virus Infection
Interventions: DRUG: valacyclovir tablet|DRUG: valacyclovir oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: In Vivo Clinical and Radiological Effects of Platelet-rich Plasma on Interstitial Supraspinatus Lesion: Randomized Study
Status: UNKNOWN
Conditions: Supraspinatis Interstitial Partial-thickness Tears|Platelet-rich Plasma (PRP)
Interventions: PROCEDURE: PRP infiltraiton|PROCEDURE: Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Efficacy of IMB-1018972 in Patients With Non-obstructive Hypertrophic Cardiomyopathy Trial
Status: COMPLETED
Conditions: Non-obstructive Hypertrophic Cardiomyopathy
Interventions: DRUG: IMB-1018972|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of N-Acetylcysteine on Peritoneal Membrane Function in Chronic Peritoneal Dialysis Patients
Status: UNKNOWN
Conditions: ESRD|Peritoneal Dialysis
Interventions: DRUG: Oral N-Acetylcysteine 1200 mg x 2/day for 4 weeks.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Autologous Non-hematopoietic Peripheral Blood Stem Cells Therapy in Healthy Adult Volunteers.
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Nebulization of autologous non-hematopoietic peripheral blood stem cells (NHPBSC).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptability of an Out-patient Regimen of Medical Abortion With Mifepristone and 800 Mcg Misoprostol Administered at 78-84 Days Gestation
Status: COMPLETED
Conditions: Medical Abortion
Interventions: DRUG: Misoprostol|DRUG: Mifepristone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Posterior Fixation Alone and Combined With Articular Process Fusion in Thoracolumbar Burst Fractures
Status: UNKNOWN
Conditions: Thoracolumbar Burst Fracture
Interventions: PROCEDURE: Fixation Combined With Fusion|PROCEDURE: Fixation Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess How Food Affects the Safety and Pharmacokinetics of Galicaftor and Navocaftor
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Galicaftor|DRUG: Navocaftor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cerebral Blood Flow-guided Early Rehabilitation Intervention After Stroke: a Pilot Randomized Trial (STAND-OP)
Status: COMPLETED
Conditions: Acute Stroke
Interventions: OTHER: Early Mobilization|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychotherapeutic Augmentation of Brain Stimulation Effects
Status: COMPLETED
Conditions: Depression Chronic|Depression, Unipolar|Treatment Resistant Depression
Interventions: BEHAVIORAL: EffEKTiv 2.0 group CBT as continuation treatment after ECT in depressed patients|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zambia Common Elements Treatment Approach Pilot Study
Status: TERMINATED
Conditions: Alcohol Use Disorder|Depression|Post-traumatic Stress Disorder|HIV/AIDS|Substance Use Disorders
Interventions: BEHAVIORAL: Brief Intervention|BEHAVIORAL: Common Elements Treatment Approach (CETA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Classical Turkish Music for Pregnant Women With Preeclampsia
Status: NOT_YET_RECRUITING
Conditions: Pre-Eclampsia
Interventions: OTHER: Experimental group: Listenning to the Turkish Classical Music to pregnant women diagnosed with preeclampsia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE