pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Randomized Study Comparing the Safety and Efficacy of Two Regimens of Oral Ganciclovir to Intravenous Ganciclovir Maintenance Therapy for Cytomegalovirus Retinitis in People With AIDS Who Have Received Prior Ganciclovir Therapy
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: An Open-label Study of Hydromorphone Oral Solution in Subjects Aged 28 Days to 16 Years for Postoperative Pain
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Hydromorphone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of the Hyperviscosity Syndrome in Waldenström Macroglobulinemia
Status: RECRUITING
Conditions: Hyperviscosity Syndrome|Waldenstrom Macroglobulinemia
Interventions: OTHER: fundoscopic picture|BIOLOGICAL: blood sample|PROCEDURE: bone marrow sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vaccine Therapy and Resiquimod in Treating Patients With Stage II-IV Melanoma That Has Been Removed By Surgery
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage IIA Melanoma|Stage IIB Melanoma|Stage IIC Melanoma|Stage IIIA Melanoma|Stage IIIB Melanoma|Stage IIIC Melanoma|Stage IV Melanoma
Interventions: DRUG: Montanide ISA 51 VG|BIOLOGICAL: MART-1 antigen|OTHER: laboratory biomarker analysis|BIOLOGICAL: Gag:267-274 peptide vaccine|DRUG: resiquimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VERU-111 in the Treatment of SARS-Cov-2 Infection by Assessing Its Effect on the Proportion of Patients Who Die on Study
Status: COMPLETED
Conditions: SARS-CoV Infection
Interventions: DRUG: VERU-111
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rejuvenated RBC and VO2 Max in Healthy Subjects
Status: TERMINATED
Conditions: Erythrocyte Transfusion
Interventions: BIOLOGICAL: Transfusion of rejuvenated and washed autolgous RBCs|BIOLOGICAL: Transfusion of washed autolgous RBCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Are Sleeping Disorders Associated With Visceral Hypersensitivity in Irritable Bowel Syndrome Patients ?
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: PROCEDURE: Barostat procedure|OTHER: Anxiety and Depression Evaluation|OTHER: Assessment of sleep quality
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Pilates &Home Exercise Programs on Muscle Strength in Paraplegic Patients
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Reformer Pilates|OTHER: Home Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TAP vs Caudal Block Using Dexmedetomidine/ Bupivacaine for Post Operative Analgesia
Status: COMPLETED
Conditions: Analgesia, Epidural
Interventions: DRUG: ultrasonography-guided TAP block|DRUG: Caudal epidural block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PET-MRI in Diagnosing Patients With Cancer, Cardiac Diseases, or Neurologic Diseases
Status: COMPLETED
Conditions: Cardiac Disease|Dementia|Inflammatory Disease|Fever of Unknown Origin|Vasculitis|Osteomyelitis|FDG Avid Cancers
Interventions: DEVICE: positron emission tomography|DEVICE: computed tomography|DEVICE: magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Pre-emptive Assessment of Self-care Peritoneal Dialysis (PD) Ability on PD Choice in Patients With Stage 5 Chronic Kidney Disease
Status: NOT_YET_RECRUITING
Conditions: Chronic Kidney Disease (CKD) Stage 5
Interventions: OTHER: Self-care PD ability assessment form|OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Epirubicin, Carboplatin, and Capecitabine in Treating Patients With Unresectable Locally Advanced, Metastatic, or Recurrent Solid Tumor
Status: COMPLETED
Conditions: Esophageal Cancer|Extrahepatic Bile Duct Cancer|Gastric Cancer|Head and Neck Cancer|Liver Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: capecitabine|DRUG: carboplatin|DRUG: epirubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Use of Norethindrone Acetate for Management of Bleeding Associated With the Etonogestrel Contraceptive Implant
Status: COMPLETED
Conditions: Etonogestrel Contraceptive Implant, Bothersome Bleeding
Interventions: DRUG: Norethindrone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Saccharomyces Boulardii CNCM I-745 on Intestinal Barrier Function
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: Indomethacin|DIETARY_SUPPLEMENT: S. boulardii CNCM I-745|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acute Kidney Injury - Biomarkers in Major Abdominal Surgery
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DIAGNOSTIC_TEST: Urinary Biomarkers (NGAL, DKK-3, IGFBP-7/TIMP-2, KIM-1)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Detecting Autologous Transfusion by Measuring Alterations in the Dynamics of Red Blood Cell Maturation and Recycling
Status: COMPLETED
Conditions: Blood Transfusion, Autologous|Blood Doping
Interventions: OTHER: Autologous Transfusion|OTHER: Control - Normal Saline (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Prilocaine 2% and Lidocaine 5% Hyperbaric Against Spinal Anesthesia in Post Cystoscopy Procedure
Status: NOT_YET_RECRUITING
Conditions: Anesthesia; Reaction|Anesthesia
Interventions: DRUG: Prilocaine 2%|DRUG: Hyperbaric Lidocaine 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Nituzumab (Taixinsheng ®） A Prospective, Randomized, Double-blind, Placebo-controlled, Multicenter Phase II Clinical Study on the Efficacy and Safety of Combined Induction Chemotherapy for Locally Advanced Nasopharyngeal Carcinomatreatment of Locally Advanced Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Nituzumab/placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cost Effectiveness of the EndoPhys Pressure Sensing Access System vs. Radial A-line for Intra-operative Blood Pressure Monitoring
Status: COMPLETED
Conditions: Cerebrovascular Disorders
Interventions: OTHER: EndoPhys Sheath and Radial Arterial Line|OTHER: EndoPhys Sheath
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nitrite-boosting Therapy for Improving Physiological Function in Patients With Chronic Kidney Disease
Status: RECRUITING
Conditions: Chronic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: Nitrate-rich beetroot juice|DIETARY_SUPPLEMENT: Nitrate-depleted beetroot juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Carotene and Retinol Efficacy Trial
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Beta Carotene and Retinol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Salvianolate Injection in Elderly Patients With Unstable Angina Pectoris
Status: UNKNOWN
Conditions: Unstable Angina
Interventions: DRUG: 0.9% Sodium Chloride Injection|DRUG: salvianolate injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intermittent Fasting Compared to Continuous Energy Restriction on Body Weight Loss
Status: NOT_YET_RECRUITING
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Intermittent energy restriction (IER) : 5:2 diet pattern|BEHAVIORAL: Continuous energy restricted (CER) group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Herbal-Based Medication vs. Placebo in Preventing Acute Otitis Media in Children at High Risk of Recurrence
Status: COMPLETED
Conditions: Acute Otitis Media
Interventions: DRUG: Herbal-based medication|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Meropenem vs Cefotaxime as Empirical Treatment of SBP
Status: UNKNOWN
Conditions: Spontaneous Bacterial Peritonitis
Interventions: DRUG: cefotaxime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Amino Acids and Sugar Alcohols on Gastric Emptying and Release of Satiation Peptides in Humans
Status: COMPLETED
Conditions: Endocrine System Diseases
Interventions: DIETARY_SUPPLEMENT: 0.52 g L-Tryptophan|DIETARY_SUPPLEMENT: 1.56 g L-Tryptophan|DIETARY_SUPPLEMENT: 1.56 g L-Leucine|DIETARY_SUPPLEMENT: 50 g Xylitol|DIETARY_SUPPLEMENT: 75 g Erythritol|DIETARY_SUPPLEMENT: 75 g Glucose|DIETARY_SUPPLEMENT: 300 mL tap water|OTHER: 50 mg 13C-sodium acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Mapping the MoA Behind GI Protection From Bif195
Status: COMPLETED
Conditions: Reduction of Small Intestinal Ulceration Risk
Interventions: DIETARY_SUPPLEMENT: Bif195|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Simulated In-House Usability Study of Eclipse Continuous Positive Airway Pressure (CPAP) Device
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Eclipse novel CPAP mask|DEVICE: Phillips Respironics Nuance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Asthma Collaboration to Reduce Childhood Asthma Disparities on the Navajo Nation
Status: ENROLLING_BY_INVITATION
Conditions: Asthma in Children
Interventions: BEHAVIORAL: Asthma Care Provider Training|BEHAVIORAL: School Staff Asthma Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Trial of SL1904B CAR-T Cells for Relapsed or Refractory Non-Hodgkin Lymphoma
Status: UNKNOWN
Conditions: Non-hodgkin's Lymphoma
Interventions: BIOLOGICAL: CD19 CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening of Microalbuminuria Using a Semi-quantitative UACR Test
Status: COMPLETED
Conditions: Diabetes|Microalbuminuria
Interventions: DIAGNOSTIC_TEST: semi-quantitative urine albumin-to-creatinine ratio test|DIAGNOSTIC_TEST: standard quantitative spot urine albumin-to-creatinine ratio
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NEOVIDEO : Impact of Monitoring Motor Activity by Video Analysis on the Sleep of Very Preterm Infants
Status: COMPLETED
Conditions: Infant Premature|Growth and Development|Neurologic Disorder|Sleep Fragmentation
Interventions: BEHAVIORAL: Access to video and movement curves
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Abbreviated 3 Cycles of Rituximab Plus CHOP(Cyclophosphamide, Adriamycin, Vincristine, and Prednisolone) Immunochemotherapy in Patients With Completely Excised LocalizedGastrointestinal CD(Cluster of Differentiation Antigen)20(+) Diffuse Large B-cell Lymphoma
Status: ENROLLING_BY_INVITATION
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Abb-R-CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mepolizumab and In-office Nasal Polypectomy in Patients With Chronic Rhinosinusitis (CRS). A Three Arm Study.
Status: NOT_YET_RECRUITING
Conditions: Rhinosinusitis Chronic|Polyp, Nasal
Interventions: DRUG: Mepolizumab|PROCEDURE: Polypeptomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expression of IL-8 Before and After Root Canal Treatment in Patients With Symptomatic Apical Periodontitis
Status: COMPLETED
Conditions: Apical Periodontitis
Interventions: PROCEDURE: Root canal instrumentation, 2.5% NaOCl irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Tetraspan 6 Percent (%) Combined With Sterofundin ISO Versus Albumin 5 Percent (%) Combined With Sodium Chloride (NaCL)
Status: TERMINATED
Conditions: Renal Insufficiency
Interventions: DRUG: HES 130/0.42 + electrolyte solution|DRUG: Albumin + electrolyte solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Embolization of the Middle Meningeal Artery for the Prevention of Chronic Subdural Hematoma Recurrence in High Risk Patients (EMPROTECT)
Status: UNKNOWN
Conditions: Chronic Subdural Hematoma|at Risk of Post-operative Recurrence|Burr-hole Surgery
Interventions: PROCEDURE: MMA embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does a Nasal Instillation of Miglustat Normalize the Nasal Potential Difference in Cystic Fibrosis Patients ?
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Miglustat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of HST 001 in Male Pattern Hair Loss
Status: COMPLETED
Conditions: Male Pattern Hair Loss
Interventions: BIOLOGICAL: HST 001|OTHER: Phosphate Buffered Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of E-cigarette Nicotine Concentration on Compensation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: OTHER: Electronic Cigarette Nicotine Concentration Order 1.8% 5% 1.8%|OTHER: Electronic Cigarette Nicotine Concentration Order 1.8% 5% 5%|OTHER: Electronic Cigarette Nicotine Concentration Order 5% 1.8% 1.8%|OTHER: Electronic Cigarette Nicotine Concentration Order 5% 1.8% 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Efficacy of Benzoyl Peroxide Regimens in Treatment of Unpleasant Foot Odor
Status: WITHDRAWN
Conditions: Benzoyl Peroxide|Foot Dermatoses
Interventions: DRUG: 2.5% benzoyl peroxide gel|DRUG: 5% benzoyl peroxide gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Topical CBD in Joint Arthritis
Status: UNKNOWN
Conditions: CBD|Hand Osteoarthritis
Interventions: DRUG: CBD|DRUG: Shea Butter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Diagnostic Adequacy of 25-gauge Fork-tip, Franseen and Reverse-bevel Type Needles in Endoscopic Ultrasound Guided Tissue Acquisition
Status: COMPLETED
Conditions: Biopsy, Needle
Interventions: DEVICE: Needle choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Imaging Biomarkers of Pancreatic Function and Disease
Status: ENROLLING_BY_INVITATION
Conditions: Pancreatitis|Diabetes Mellitus
Interventions: DIAGNOSTIC_TEST: Research MRI without administration of intravenous secretin|DIAGNOSTIC_TEST: Research MRI with administration of intravenous secretin|GENETIC: Genetic Sequencing|DIAGNOSTIC_TEST: Blood Tests|DIAGNOSTIC_TEST: Stool Tests|OTHER: Survey Completion|DIAGNOSTIC_TEST: Endoscopic pancreatic function tests (ePFTs)|DRUG: Secretin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Active Immunization of Patients With Carcinoma of Oral Cavity or Oropharynx With Autologous Dendritic Cells Transfected With DNA From Autologous Tumor
Status: TERMINATED
Conditions: Primary Advanced Carcinoma of the Oral Cavity or Oropharynx|Squamous Cell Carcinoma of the Head and Neck
Interventions: BIOLOGICAL: autologous monocyte-derived dendritic cells (DC) transfected with DNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of High-Grade Pre-Neoplastic Cervical Lesions (CIN 2/3)
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia|Cervical Dysplasia
Interventions: DRUG: 9-valent HPV vaccine|DRUG: Imiquimod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: VenaSeal Spectrum: Global Post-Market Randomized Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Venous Reflux
Interventions: DEVICE: VenaSeal™ Closure System|DEVICE: Endothermal Ablation (ETA)|PROCEDURE: Surgical Stripping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of VT Ablation Outcomes Using Remote MAGNETIC Navigation Versus Manual Approach in a Low LVEF Population
Status: TERMINATED
Conditions: Tachycardia, Ventricular
Interventions: DEVICE: catheter ablation using magnetic navigation|DEVICE: catheter ablation using manual navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Renal Cell Carcinoma and Stage IV Inferior Vena Cava Thrombus: Resection Without Thoracotomy
Status: COMPLETED
Conditions: Renal Cell Carcinoma Stage III
Interventions: PROCEDURE: Radical nephrectomy with inferior vena cava thrombectomy without thoracotomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Potential of CCX168 With Concomitant Medications
Status: COMPLETED
Conditions: Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis
Interventions: DRUG: CCX168|DRUG: Midazolam|DRUG: Celecoxib|DRUG: Itraconazole|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Alternative Diets During the Stabilization Phase on Children With Complicated SAM
Status: COMPLETED
Conditions: Severe Acute Malnutrition|Kwashiorkor|Nutritional Edema|Marasmus
Interventions: DIETARY_SUPPLEMENT: Standard F75|DIETARY_SUPPLEMENT: Alternative F75 with CMV|DIETARY_SUPPLEMENT: Alternative F75 without CMV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Versus Superficial Heating in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Microwave diathermy|OTHER: Superficial hyperthermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of 2 Multifocal Intraocular Lenses in Heidelberg
Status: RECRUITING
Conditions: Cataract
Interventions: DEVICE: intraocular lens implantation in cataract surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Yoga Pranayama Adjuvant to Treat Burden COVID-19
Status: UNKNOWN
Conditions: Coronavirus Infection|Cytokine Storm|Mental Disorder
Interventions: BEHAVIORAL: morning Yoga-based breathing support|BEHAVIORAL: pre_lunch Yoga-based breathing support|BEHAVIORAL: pre_dinner Yoga-based breathing support
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Antiemetic Efficacy and Safety of Dexamethasone in Obstetric Surgical Patients
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: dexamethasone|OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Histologic Evaluation of Tissue Following Lutronic System Exposure
Status: UNKNOWN
Conditions: Abdominoplasty
Interventions: DEVICE: Genius|DEVICE: eC02|DEVICE: PicoPlus|DEVICE: LaseMD|DEVICE: LaseMD Flex
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of Factors Favoring The Onset Of Novo Atrial Fibrillation In The Immediate Aftermath Of Coronary Artery Bypass Surgery
Status: COMPLETED
Conditions: Coronary Artery Bypass Graft With or Without ECC
Interventions: OTHER: Tissue samples from the right atrium|OTHER: Blood samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment With IFN After Curative Resection of HCC in HCV-Related Cirrhosis
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Hepatitis C Virus Infection|Liver Cirrhosis|Interferon Treatment|Hepatic Resection
Interventions: DRUG: Interferon alpha-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 24-hour Ambulatory Blood Pressure Monitoring in Patients With Blood Pressure Above Thresholds in General Practice
Status: UNKNOWN
Conditions: Hypertension|Blood Pressure Monitoring, Ambulatory|Primary Health Care
Interventions: DEVICE: 24-hour Ambulatory Blood Pressure Monitoring (ABPM)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of SD-101 in Combination With Localized Low-dose Radiation in Patients With Untreated Low-grade B-cell Lymphoma
Status: TERMINATED
Conditions: B-cell Lymphoma
Interventions: DRUG: SD-101|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Moderate Malnutrition in 6-24 Months Old Children
Status: COMPLETED
Conditions: Moderate Acute Malnutrition
Interventions: DIETARY_SUPPLEMENT: Ready-to-Use Therapeutic Food (RUTF)|DIETARY_SUPPLEMENT: CBS++|BEHAVIORAL: CCC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Pharmacology Study to Evaluate the Effect of GYM329 on Disuse Muscle Atrophy in Healthy Volunteer
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: GYM329|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Loop Diuretic Dosage in Patients With Acute Heart Failure and Renal Failure: Conventional Versus Carbohydrate Antigen 125-guided Therapy (IMPROVE-HF)
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: CA125 guided strategy|DRUG: CA125 guided strategy|DRUG: Conventional Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Whether Proton Pump Inhibitors, Administered Prior to or After Surgery, Can Reduce the Incidence and/or Severity of Difficulty Swallowing Foods and/or Liquids,Following Anterior Cervical Surgery
Status: WITHDRAWN
Conditions: Dysphagia|GERD|Degenerative Joint Disease
Interventions: DRUG: Esomeprazole|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Repetitive Transcranial Magnetic Stimulation With Precision Neuronavigation in Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease|Transcranial Magenetic Stimualtion|Supplementary Motor Area
Interventions: OTHER: transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Two Dosages of Diractin® in Osteoarthritis (OA)
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: ketoprofen in Diractin®|DRUG: ketoprofen in Diractin®|DRUG: Placebo|DRUG: celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Enteral Nutrition Feeding in Parkinson Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Intermittent Oro-esophageal Tube|DEVICE: Nasogastric tube|BEHAVIORAL: Comprehensive rehabilitation training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nal-IRI and 5-FU Compared to 5-FU in Patients With Cholangio- and Gallbladder Carcinoma Previously Treated With Gemcitabine-based Therapies
Status: COMPLETED
Conditions: Cholangiocarcinoma Non-resectable|Cholangiocarcinoma Metastatic|Cholangiocarcinoma of the Gallbladder|Cholangiocarcinoma Advanced
Interventions: DRUG: nal-IRI|DRUG: 5-FU|DRUG: leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY03003 in Patients With Early-stage Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Rotigotine, extended-release microspheres|DRUG: Placebo, extended-release microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biodistribution and Dosimetry of Serial PET Imaging With Ga-68 Labeled F(ab') 2- Trastuzumab
Status: COMPLETED
Conditions: Solid Tumors
Interventions: RADIATION: PET Imaging with Ga-68 Labeled F(ab') 2- Trastuzumab|RADIATION: PET Imaging with Ga-68 Labeled F(ab') 2- Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Safety and Effectiveness of Retrovir Plus HIVID Combined With Either Nevirapine or Invirase in the Treatment of HIV Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Saquinavir|DRUG: Nevirapine|DRUG: Zidovudine|DRUG: Zalcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Exercise Therapies for Patellofemoral Pain
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Quadriceps Exercise program|OTHER: Hip Exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Anti-PD-1 AK105 in Patients With Relapsed or Refractory Classic Hodgkin Lymphoma
Status: COMPLETED
Conditions: Hodgkin's Lymphoma
Interventions: BIOLOGICAL: AK105
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery in People With or Without Kidney Disease
Status: RECRUITING
Conditions: Intraoperative Ureter Visualization|Abdominolpelvic Surgery
Interventions: DRUG: pudexacianinium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Middle Meningeal Artery Embolization for Chronic Subdural Hematomas (STORMM)
Status: NOT_YET_RECRUITING
Conditions: Chronic Subdural Hematomas|Cerebral Compression Due to Injury
Interventions: RADIATION: MMA embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cohort Study for the Assessment of Long-term Impact of COVID-19 Among Mild COVID-19 Patients in Brazil
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19|Quality of Life|Disability Physical|Disabilities Mental
Interventions: OTHER: Patients with symptomatic COVID-19 disease not requiring hospitalization.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility and Efficacy of a Digital Neurotherapy Protocol for Management of Depression, Cognition, and Quality of Life in Cancer Survivors
Status: RECRUITING
Conditions: Depression|Cognition|Quality of Life
Interventions: BEHAVIORAL: Digital neurotherapy (DNT) Treatment|BEHAVIORAL: Wait list control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Transition to Adulthood Education Program on Family Quality of Life and Perceived Stress Level
Status: COMPLETED
Conditions: Intellectual Disability
Interventions: OTHER: Transition to Adulthood Education Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cervical Ripening in Obese Women: Efficacy of 25 mcg Versus 50 mcg of Misoprostol
Status: UNKNOWN
Conditions: Induction of Labor Affected Fetus / Newborn
Interventions: DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Morning Versus Evening Dosing of Antihypertensive Medications: A Pilot Study to Assess Feasibility and Efficacy
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Medication therapy management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: ADAPT Study: Long-term Safety Study of INZ-701 in Patients With ENPP1 Deficiency and ABCC6 Deficiency
Status: RECRUITING
Conditions: Gene Mutations|Pseudoxanthoma Elasticum|Arterial Calcification|Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency|Autosomal Recessive Hypophosphatemic Rickets Type 2
Interventions: DRUG: INZ-701
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability and Bioequivalence of Ezetimibe Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Hyperlipidemias
Interventions: DRUG: ezetimibe tablet|DRUG: ezetimibe tablet(Ezetrol ®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Durvalumab (MEDI4736) After Chemo-Radiation for Microsatellite Stable Stage II-IV Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DRUG: durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Soy Protein on Cholesterol Levels in Children Affected With Familial Hypercholesterolemia
Status: COMPLETED
Conditions: Heterozygous Familial Hypercholesterolemia
Interventions: BEHAVIORAL: Dietary counseling (fat modifed diet)|BEHAVIORAL: Dietary Counseling (fat modified + soy enriched diet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin Hydrochloride in Mitigating Side Effects of Radioactive Iodine Treatment in Patients With Differentiated Thyroid Cancer
Status: COMPLETED
Conditions: Thyroid
Interventions: DRUG: Metformin Hydrochloride|OTHER: Radioactive Iodine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preoperative Detection of Lymph Node Metastases in Pancreatic and Periampullary Carcinoma Using USPIO MRI
Status: TERMINATED
Conditions: Pancreatic Cancer|Periampullary Cancer
Interventions: DIAGNOSTIC_TEST: USPIO-enhanced MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized Study Using SM-030 Gel for Adults With Melasma
Status: RECRUITING
Conditions: Melasma
Interventions: DRUG: SM-030 gel 0.64%|DRUG: Placebo gel|DRUG: SM-030 gel 0.08%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Painful Chronicization After Knee Replacement Surgery : Exploratory Study of BDNF's Kinetics
Status: COMPLETED
Conditions: Total Knee Arthroplasty|Chronic Postoperative Pain
Interventions: DIAGNOSTIC_TEST: blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Interest of the Addition of Docetaxel to Standard Treatment in First-line Advanced HER2 Positive Gastroesophageal Adenocarcinoma in Selective Patients
Status: COMPLETED
Conditions: HER2-positive Gastric Cancer|Metastatic Cancer|Docetaxel|Trastuzumab
Interventions: DRUG: Taxane
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Dose Intravenous Ascorbic Acid in Severe Sepsis
Status: TERMINATED
Conditions: Sepsis
Interventions: DRUG: Ascorbic Acid|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Computer Aided Design and 3D Printing for Anesthesiology Management in a Pediatric Patient With Cleft Facial Defect
Status: RECRUITING
Conditions: Cleft Lip and Palate
Interventions: DEVICE: 3D obturator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Outcome of Coracoclavicular Ligament Repair Using Autogenous Gracilis Tendon in Endobutton System.
Status: UNKNOWN
Conditions: Acromioclavicular Joint Dislocation.
Interventions: PROCEDURE: Surgical treatment of acromioclavicular dislocation.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of Biological Activity of Enriched Serum Following TOTUM-448 Consumption
Status: COMPLETED
Conditions: NAFLD|MASLD|Mild Inflammatory Context
Interventions: DIETARY_SUPPLEMENT: TOTUM-448
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial to Evaluate the Characteristics of Patients Treated for Advanced Renal Cell Carcinoma With Nexavar ®
Status: COMPLETED
Conditions: Carcinoma, Renal Cell|Carcinoma, Renal Cell (Advanced)
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: OXXYNEA® GS: Study for Glycaemia Management
Status: RECRUITING
Conditions: Prediabetic State|Overweight
Interventions: DIETARY_SUPPLEMENT: Verum A|DIETARY_SUPPLEMENT: Verum B|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evidence Based Decision Making: Integrating Clinical Prediction Rules
Status: COMPLETED
Conditions: Strep Pharyngitis|Pneumonia
Interventions: OTHER: Integrated Clinical Prediction Rule (iCPR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: MRP Verses PNF On Pain, Foot Drop, Gait And Functional Mobility In Hemiplegic Patients.
Status: RECRUITING
Conditions: Stroke|Pain|Gait, Drop Foot|Foot Drop|Hemiplegia
Interventions: COMBINATION_PRODUCT: Motor Relearning Program with Electrical Muscle Stimulation (MRA + EMS)|COMBINATION_PRODUCT: Proprioceptive Neuromuscular Facilitation Technique with Electrical Muscle Stimulation (PNF + EMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Set-back Suture Versus Traditional Vertical Mattress Suture
Status: COMPLETED
Conditions: Basal Cell Carcinoma|Squamous Cell Carcinoma|Melanoma
Interventions: PROCEDURE: Set-back suture|PROCEDURE: Vertical mattress suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A 3-part Study to Evaluate Safety, Tolerability, Food Effect and Drug-drug Interactions of RXC007 in Healthy Volunteers
Status: COMPLETED
Conditions: Fibrosis|Inflammation|Idiopathic Pulmonary Fibrosis|Non-alcoholic Steatohepatitis|Liver Diseases|Kidney Diseases
Interventions: DRUG: RXC007|DRUG: RXC007 Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study for Desensitization of Chronic Kidney Disease in Adult Patients in Need of a Kidney Transplant Who Are Highly Sensitized to Human Leukocyte Antigen
Status: RECRUITING
Conditions: Chronic Kidney Disease (CKD)
Interventions: DRUG: REGN5459|DRUG: REGN5458
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin K as Additive Treatment in Osteoporosis
Status: UNKNOWN
Conditions: Post-menopausal Osteoporosis
Interventions: DRUG: Phylloquinone|DRUG: Menatetrenone (MK4)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Proof-of-Concept, Safety and Efficacy Study of SkinQ Glow Bright Wonder Mask in Healthy Human Subjects
Status: COMPLETED
Conditions: Healthy Human Volunteers With Visibly Tanned Skin
Interventions: OTHER: SkinQ Glow Bright Wonder Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Seventh Generation Bonding Agents as Short-Term Desensitizers Among Patients With Hypersensitivity
Status: COMPLETED
Conditions: Dentin Hypersensitivity
Interventions: DRUG: Single Bond Universal|DRUG: Bifluorid 12|DRUG: Xeno V+
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of 2 Medicines (Aztreonam and Avibactam) Compared to Best Available Therapy for Serious Gram-negative Infections
Status: RECRUITING
Conditions: Gram-negative Bacterial Infections
Interventions: DRUG: ATM-AVI|DRUG: BAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Digital Flow Enhancement in Raynaud's Phenomenon With an sGC (Soluble Guanylate Cyclase) Stimulator
Status: COMPLETED
Conditions: Raynaud Disease
Interventions: DRUG: Riociguat (Adempas, BAY63-2521)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Topical Penlac Nail Lacquer for Onychomycosis in Children
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DRUG: Ciclopirox|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study to Evaluate Marqibo® in the Treatment of Subjects ≥ 60 Years Old With Newly Diagnosed ALL
Status: TERMINATED
Conditions: Acute Lymphoblastic Leukemia (ALL)
Interventions: DRUG: Vincristine Sulfate Liposomes Injection (VSLI)|DRUG: Vincristine Sulfate Injection (VSI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sedation With Dexmedetomidine Versus Remifentanil in Urogynecological Surgery Under Spinal Anaesthesia
Status: UNKNOWN
Conditions: Vaginal Hysterectomy|Suburethral Slings
Interventions: DRUG: Dexmedetomidine|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Soy and Isoflavones Effect on Bone
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DIETARY_SUPPLEMENT: Soy Isolate|DIETARY_SUPPLEMENT: Control protein|DIETARY_SUPPLEMENT: Novasoy isoflavones|DIETARY_SUPPLEMENT: Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurobiology of Treatment Responses in MDD
Status: WITHDRAWN
Conditions: Major Depressive Disorder
Interventions: DRUG: Duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Postoperative Knee Strength Following Total Knee Replacement: A Double-Blinded Randomized Comparison Study
Status: COMPLETED
Conditions: Total Knee Replacement|Primary Knee Arthroplasty
Interventions: DRUG: Fentanyl|DRUG: Ropivacaine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Random Noise Stimulation in Food Addiction Treatment
Status: TERMINATED
Conditions: Overweight, Obesity and Other Hyperalimentation (E65-E68)
Interventions: DEVICE: Active tRNS|DEVICE: Sham tRNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study Assessing Blood Pressure and Other Outcomes Post-treatment in Patients With Primary Aldosteronism
Status: COMPLETED
Conditions: Primary Aldosteronism|Primary Aldosteronism Due to Aldosterone Producing Adenoma|Primary Aldosteronism Due to Adrenal Hyperplasia (Bilateral)
Interventions: PROCEDURE: Adrenalectomy|DRUG: Mineralocorticoid Receptor Antagonists
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sputum Microbiota and the Association With Clinical Parameters in Steady-state, Acute Exacerbation and Convalescence of Bronchiectasis
Status: UNKNOWN
Conditions: Bronchiectasis
Interventions: DRUG: Antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of IDP-120 Gel in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: IDP-120 Gel|DRUG: IDP 120 Component A Gel|DRUG: IDP 120 Component B Gel|DRUG: IDP 120 Vehicle Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Effectiveness and Parental Acceptance of Silver Diamine Fluoride in Preschool Children: A Non-randomized Trial
Status: COMPLETED
Conditions: Silver Diamine Fluoride
Interventions: DRUG: Silver Diamine Fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT