pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: SCO2T (Servo vs. Servo)
Status: TERMINATED
Conditions: Premature Infant|Oxygen Therapy|Hypoxia|Hyperoxia|Obstetric Labor, Premature
Interventions: DEVICE: Servo control (closed-loop automatic control of the inspiratory fraction of oxygen (FiO2)) - Leoni plus CLAC|DEVICE: Servo control (closed-loop automatic control of the inspiratory fraction of oxygen (FiO2)) - IntellO2 OAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Body and Brain Exercise for Older Adults With Memory Complaints
Status: COMPLETED
Conditions: Cognitive Ability, General
Interventions: BEHAVIORAL: Multi-modal exercise|BEHAVIORAL: Mind-Motor Exercise|BEHAVIORAL: Balance and range of motion exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: B Vitamins in MTHFR Positive Patients With Major Depression: A Post Hoc Analysis of Findings
Status: COMPLETED
Conditions: Depression
Interventions: DIETARY_SUPPLEMENT: Enlyte|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Combination of Venetoclax and Obinutuzumab in People With Chronic Lymphocytic Leukemia (CLL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia (CLL)
Interventions: DRUG: Obinutuzumab|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of BI 10773 in Combination With Insulin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: BI 10773 placebo|DRUG: BI 10773 low dose|DRUG: BI 10773 high dose|DRUG: BI 10773 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Two Yogurt Formulations in Healthy Humans
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: L. Amylovorus|DIETARY_SUPPLEMENT: L. Fermentum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Pharmacokinetics of C3G and to Estimate Antioxidative Markers After Repeated Administration of Mulberry Fruit Extract
Status: COMPLETED
Conditions: Oxidative Stress
Interventions: OTHER: Mulberry fruit extract
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Access Anti-HAV and Access Anti-HAV IgM Assays EU Clinical Trial Protocol (HAV-EU-11-23)
Status: RECRUITING
Conditions: HAV
Interventions: DIAGNOSTIC_TEST: Access anti-HAV and Access anti-HAV IgM on the DxI 9000 Access Immunoassay Analyzer and CE-marked predicate assays|DIAGNOSTIC_TEST: Access anti-HAV on the DxI 9000 Access Immunoassay Analyzer and CE-marked predicate assays
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Belantamab Mafodotin as Pre- and Post-autologous Stem Cell Transplant and Maintenance for Multiple Myeloma
Status: RECRUITING
Conditions: Myeloma
Interventions: DRUG: Belantamab mafodotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cutaneous Anesthesia of the Lateral Femoral Cutaneous Nerve
Status: COMPLETED
Conditions: Nerve Block|Anesthesia, Local|Pain, Postoperative|Anatomical Distribution|Nervus Cutaneous Femoris Lateralis|Lateral Femoral Cutaneous Nerve
Interventions: DRUG: Ropivacaine Injection|DRUG: Ropivacaine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Immune Response of an H7N7 Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Influenza A Subtype H7N7 Infection
Interventions: BIOLOGICAL: Monovalent Influenza Subvirion Vaccine, H7N7
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Zaleplon 10 mg Capsules Under Non-Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Zaleplon 10 mg Capsules|DRUG: SONATA® 10 mg capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Continuous TAP Blocks - Pain & Plasma LA Levels
Status: TERMINATED
Conditions: Nerve Block|Pain, Postoperative
Interventions: PROCEDURE: TAP block|PROCEDURE: Sham TAP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Albumin-bound Paclitaxel Plus S-1 Versus SOX as First-line Treatment in Advanced or Recurrent Gastric Adenocarcinoma
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Albumin-bound Paclitaxel plus S-1|DRUG: Oxaliplatin plus S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of Different Prostate Surgeries on Urinary and Sexual Function
Status: COMPLETED
Conditions: Sexual Functions and Problems in the Adult
Interventions: PROCEDURE: Holmium laser enucleation of the prostate|PROCEDURE: Monopolar transurethral resection of the prostate|PROCEDURE: Bipolar transurethral resection of the prostate|PROCEDURE: Diagnostic cystoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Survival According to the Feeding Artery Obliteration by Chemoembolization for Unresectable Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Transarterial Chemoembolization
Interventions: PROCEDURE: Intermediate embolization|PROCEDURE: Complete embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Pharmacokinetic and Tolerance Study of 28-Day Regimens of Oral Ganciclovir
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Trial of PET/CT vs. CTSurveilance for Head and Neck Cancer
Status: TERMINATED
Conditions: Carcinoma, Squamous Cell of Head and Neck
Interventions: OTHER: PET/CT|OTHER: Computed Tomography (CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Platelet Transfusion During Neonatal Open Heart Surgery
Status: COMPLETED
Conditions: Cardiac Disease|Cardiac Surgery|Cardiopulmonary Bypass|Platelet Transfusion|Arrythmia, Cardiac|Mortality
Interventions: BIOLOGICAL: Platelet Transfusion|BIOLOGICAL: FFP and Cryoprecipitate|BIOLOGICAL: PRBC and cell saver Transfusion|BIOLOGICAL: Factor Concentrate (Bebulin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Internet-based vs Face-to-face Cognitive Behavioural Therapy for Obsessive-compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-compulsive Disorder
Interventions: BEHAVIORAL: Cognitive-behavioral therapy (face-to-face)|BEHAVIORAL: Internet-based Cognitive-behavioral therapy|BEHAVIORAL: Internet-based Cognitive-behavioral therapy without therapist support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Delirium in Patients Undergoing Radical Cystectomy
Status: COMPLETED
Conditions: Post-operative Delirium
Interventions: BEHAVIORAL: Assessments|PROCEDURE: Blood Draw|OTHER: Standardized Anesthetic Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effectiveness, Safety, Adherence, and Health-related Quality of Life in HIV-1 Infected Adults Receiving Bictegravir/ Emtricitabine/Tenofovir Alafenamide
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: DRUG: B/F/TAF
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of VITLS Compared to Traditional Inpatient Monitoring in Cardiac Shunt-Dependent Children
Status: COMPLETED
Conditions: Congenital Heart Disease|Desaturation of Blood
Interventions: DEVICE: VITLS Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Double-blind Randomized Controlled Trial of a Thickened Amino-acid-based Formula in Children Allergic to Cow's Milk and to Protein Hydrolysates
Status: COMPLETED
Conditions: Cow Milk Allergy
Interventions: DIETARY_SUPPLEMENT: Amino acid based formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Breast-Conserving Surgery and Whole-Breast Radiation Therapy With or Without Additional Radiation Therapy to the Tumor in Treating Women With Ductal Carcinoma in Situ (BONBIS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: partial breast irradiation|RADIATION: whole breast irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine, Vorinostat, and Radiation Therapy in Treating Patients With Nonmetastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer|Periampullary Adenocarcinoma
Interventions: DRUG: capecitabine|DRUG: vorinostat|RADIATION: Radiotherapy|PROCEDURE: Surgery to remove tumor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Response Study of Patients With Erythematous Rosacea
Status: COMPLETED
Conditions: Erythematous (Type One) Rosacea
Interventions: DRUG: V-101|OTHER: vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Histology From a Mesh Sponge and Traditional Esophageal Biopsies in Children and Adolescents With EoE
Status: UNKNOWN
Conditions: Eosinophilic Esophagitis
Interventions: DIAGNOSTIC_TEST: Using a swallowed expanding sponge (Cytosponge TM) to obtain sampling of the esophageal musosa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Reduced Intensity Conditioning Before Partially Matched Donor Stem Cell Transplant in Treating Patients With Advanced Cutaneous T Cell Lymphoma
Status: WITHDRAWN
Conditions: Cutaneous T-Cell Non-Hodgkin Lymphoma|Recurrent Mycosis Fungoides and Sezary Syndrome|Stage IIB Mycosis Fungoides and Sezary Syndrome|Stage IIIA Mycosis Fungoides and Sezary Syndrome|Stage IIIB Mycosis Fungoides and Sezary Syndrome|Stage IVA Mycosis Fungoides and Sezary Syndrome|Stage IVB Mycosis Fungoides and Sezary Syndrome
Interventions: DRUG: Fludarabine|RADIATION: Total-Body Irradiation|BIOLOGICAL: T Cell-Depleted Donor Lymphocyte Infusion|DRUG: Cyclophosphamide|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|PROCEDURE: Peripheral Blood Stem Cell Transplantation|DRUG: Mycophenolate mofetil|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antineoplaston Therapy in Treating Children With Low-Grade Astrocytoma
Status: COMPLETED
Conditions: Low Grade Astrocytomas
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of BI 409306 After a High Fat, High Caloric Meal and After a Single Oral Dose Given at Bed Time in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 409306
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Youth Opioid Recovery Support: A Developmentally-specific Intervention for Home Delivery of Extended Release Naltrexone
Status: COMPLETED
Conditions: Opioid-Related Disorders
Interventions: BEHAVIORAL: Youth Opioid Recovery Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Placebo-Controlled, Multidose, Study Comparing Generic Budesonide/Formoterol Fumarate Dihydrate to Symbicort® in Asthmatic Participants
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Generic Budesonide/Formoterol Fumarate Dihydrate|DRUG: Symbicort® (Budesonide/Formoterol Fumarate Dihydrate)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Casting of Displaced Pediatric Distal Forearm Fractures Non-inferior to Reduction in General Anesthesia?
Status: RECRUITING
Conditions: Distal Forearm Fracture|Distal Radius Fracture
Interventions: PROCEDURE: Non-surgical treatment|PROCEDURE: Surgical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nimotuzumab Plus Nab-paclitaxel and Cisplatin in Treating Patients With Advanced Esophageal Carcinoma
Status: WITHDRAWN
Conditions: Stage IV Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Nimotuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Mental Health Effects of a Mindfulness App in Parents of a Child With Medical Complexity
Status: COMPLETED
Conditions: Depression|Family Dynamics|Stress, Psychological|Chronic Illness|Parents
Interventions: BEHAVIORAL: mindfulness app
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Low-intensity Shockwave vs Radial Wave for Treatment of Erectile Dysfunction and Pelvic Pain
Status: RECRUITING
Conditions: Erectile Dysfunction Due to Arterial Insufficiency|Erectile Dysfunction|Erectile Dysfunction Due to Arterial Disease|Chronic Pelvic Pain Syndrome|Chronic Prostatitis|Erectile Dysfunction Following Radical Prostatectomy|Erectile Dysfunction Following Radiation Therapy
Interventions: DEVICE: Focused shockwave|DEVICE: Radial wave|DEVICE: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combretastatin A4 Phosphate in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: fosbretabulin disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The JET Study: a Phase I Trial of Cabazitaxel, Radiotherapy and Long-term Androgen Deprivation
Status: WITHDRAWN
Conditions: Prostatic Neoplasms
Interventions: DRUG: cabazitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cumulative Live Birth After Double Stimulation Protocol Versus Antagonist Protocol for Poor Ovarian Responders
Status: NOT_YET_RECRUITING
Conditions: Infertility
Interventions: PROCEDURE: Double Stimulation Protocol|PROCEDURE: Antagonist Stimulation Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zoledronic Acid in the Treatment of Breast Cancer With Minimal Residual Disease in the Bone Marrow
Status: TERMINATED
Conditions: Primary Breast Cancer
Interventions: DRUG: Zoledronic acid + Calcium/Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Prospective, Randomized, Double-Blind Clinical Trial Comparing Itraconazole Oral Solution in Cyclodextrin to Placebo in the Treatment of Aspergilloma
Status: COMPLETED
Conditions: Aspergillosis|Lung Diseases, Fungal
Interventions: DRUG: Itraconazole oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Flaxseed Supplement on Weight and Biochemical Factors in Overweight and Obese Subject
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: flaxseed|DIETARY_SUPPLEMENT: Placebo|BEHAVIORAL: Exercise recommendation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monitoring and Peer Support to Improve Treatment Adherence and Outcomes
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Obstructive Sleep Apnea
Interventions: OTHER: Peer support|OTHER: Online platform|OTHER: Respiratory Therapist support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Efficacy and Safety of Meloxicam Suppository (15mg Daily) and Tablet (15 mg Daily) Compared to Indomethacin Suppository (50 mg Daily) in Patients With Ankylosing Spondylitis
Status: COMPLETED
Conditions: Spondylitis, Ankylosing
Interventions: DRUG: Meloxicam suppository|DRUG: Meloxicam tablet|DRUG: Indomethacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Efficacy of Peroneal Transcutaneous NeuroModulation in Subjects With Parkinson's Disease and Essential Tremor
Status: COMPLETED
Conditions: Parkinson's Disease|Essential Tremor
Interventions: DEVICE: Peroneal electrical transcutaneous neuromodulation (peroneal eTNM®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Infant Formula Supports Adequate Growth in Healthy Infants
Status: UNKNOWN
Conditions: Infant Development
Interventions: OTHER: Formula A|OTHER: Formula B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Twice Daily Application of Coconut Oil in Reducing Water Loss From Skin of Premature Babies in First Week of Life
Status: COMPLETED
Conditions: Trans Epidermal Water Loss
Interventions: PROCEDURE: Coconut Oil Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Preparatory Education on Parental Stress and Attitudes in Parents of Children Entering Early Adolescence
Status: NOT_YET_RECRUITING
Conditions: Adolescent Development
Interventions: BEHAVIORAL: training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Pharmacokinetic Drug Interaction and Tolerance Study of Paracetamol and Nefopam
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: paracetamol 1000 mg per os, nefopam 60mg per os, paracetamol 1000 mg + nefopam 60 mg per os
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subtotal Versus Total Thyroidectomy for Graves' Disease
Status: COMPLETED
Conditions: Thyroid|Goiter
Interventions: PROCEDURE: Bilateral subtotal thyroidectomy|PROCEDURE: Total thyroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dual Attention in an EMDR Intervention
Status: ENROLLING_BY_INVITATION
Conditions: Trauma, Psychological|Traumatic Stress Disorder
Interventions: BEHAVIORAL: A comprehensive third-generation intervention EMDR + dual attention|BEHAVIORAL: A comprehensive third-generation intervention EMDR + fixed point|BEHAVIORAL: A comprehensive third-generation intervention EMDR + exposition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of Camrelizumab Combined With Famitinib for Adjuvant Treatment of Stage II-IIIA NSCLC.
Status: UNKNOWN
Conditions: NSCLC
Interventions: DRUG: Camrelizumab|DRUG: Famitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Circulating Biomarker Signatures for the Detection of Gastric Preneoplasia and Cancer
Status: RECRUITING
Conditions: Gastric Lesion|Gastric Precancerous Condition|Gastric Cancer
Interventions: PROCEDURE: Additional blood collection as part of routine care|PROCEDURE: Blood collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: EUS-FNA of Solid Pancreatic Mass: Comparison Between Negative Pressure and Slow-pull Technique
Status: COMPLETED
Conditions: Pancreatic Neoplasm
Interventions: PROCEDURE: Endoscopic ultrasound-guided fine needle aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase III Study of Human Papillomavirus (HPV)-16/18 Vaccine.
Status: COMPLETED
Conditions: Human Papilloma Virus Infection Type 16|Human Papilloma Virus Infection Type 18|Cervical Intraepithelial Neoplasia
Interventions: BIOLOGICAL: HPV-16/18 vaccine|BIOLOGICAL: HPV-16/18 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stem Cells and Secretomes for Infertility Therapy in Polycystic Ovary Syndrome (PCOS) Patients With Insulin Resistance.
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: BIOLOGICAL: UC-MSCs|BIOLOGICAL: Secretomes|BIOLOGICAL: UC-MSCs and Secretomes|BIOLOGICAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Micro-fragmented Adipose Tissue Injection for Knee Osteoarthritis.
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Microfragmented Adipose Tissue (Lipogems)|DRUG: Corticosteroid injection|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Triamcinolone Ketorolac (TriKe) Knee Trial
Status: RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Triamcinolone acetonide-Ketorolac-Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Primal Reflex Release Technique in Chronic Non-specific Low Back Pain
Status: UNKNOWN
Conditions: Chronic Non-specific Low Back Pain
Interventions: OTHER: Control group (conventional therapy)|OTHER: Primal Reflex release Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Triamcinolone Acetonide DuraPeel to Treat Hand Dermatitis
Status: COMPLETED
Conditions: Hand Dermatoses
Interventions: DRUG: Triamcinolone Acetonide (TAC) DuraPeel|DRUG: Placebo DuraPeel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Insulin-like Growth Factor (IGF)-Methotrexate Conjugate in the Treatment of Advanced Tumors Expressing IGF-1R
Status: COMPLETED
Conditions: Breast Cancer|Brain Cancer|Gastrointestinal Cancers|Genitourinary Cancers|Gynecologic Cancers|Head and Neck Cancers|Melanoma|Thoracic Cancers
Interventions: DRUG: IGF-Methotrexate conjugate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of PBK_L1704 for the Treatment of Moderate to Severe Acute Pain After Bunionectomy in South Korea
Status: UNKNOWN
Conditions: Acute Pain
Interventions: DRUG: PBK_L1704 0.35mg|DRUG: PBK_L1704 0.5mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment With Erythropoietin and Cognition During Hypoglycaemia
Status: COMPLETED
Conditions: Type 1 Diabetes|Hypoglycemia
Interventions: DRUG: Epoetin alfa|DRUG: Isotonic NaCl (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Efficacy and Safety of Tegaserod 6 mg Bid Given Orally to Chinese Patients With Chronic Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Tegaserod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Rituximab, Venetoclax, and Bortezomib for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Status: WITHDRAWN
Conditions: High Grade B-Cell Lymphoma, Not Otherwise Specified|Recurrent Burkitt Lymphoma|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements|Refractory Burkitt Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements
Interventions: DRUG: Bortezomib|BIOLOGICAL: Rituximab|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Children's Learning Centers Group FNI
Status: COMPLETED
Conditions: Relation, Mother-Child|Family Conflict|Emotional Disturbances|Behavior Problem|Development Delay
Interventions: BEHAVIORAL: Family Nurture Intervention (FNI)|BEHAVIORAL: Standard Children's Learning Center (CLC) Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Palliative Care Referral System (PCRS) for Cancer Patients With Advanced Disease
Status: RECRUITING
Conditions: Advanced Cancer
Interventions: OTHER: Palliative Care Referral System - PCRS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: To Determine the Metabolomics and Microbiome Changes After Cranberry Juice Consumption Among Young Women
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Cranberry juice|OTHER: Placebo juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Efficacy and Safety of Adapalene-Clindamycin Combination Gel in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: COMBINATION_PRODUCT: Adapalene-Clindamycin Combination Gel|DRUG: Adapalene Gel|DRUG: Clindamycin Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IVI-guided Versus Angiography-guided PCI in Patients With Diabetes Mellitus
Status: RECRUITING
Conditions: Diabetes
Interventions: PROCEDURE: Intravascular imaging-guided PCI|PROCEDURE: Angiography-guided PCI group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Efficiency of Artificial Intelligence for Surgical Neuropathology
Status: UNKNOWN
Conditions: Central Nervous System Neoplasms
Interventions: DIAGNOSTIC_TEST: Artificial Intelligence|DIAGNOSTIC_TEST: Practicing Pathologists|DIAGNOSTIC_TEST: Gold Standard
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Bridging the Health Disparities Gap in Decision-Making Among Limited English Proficient (LEP) Patients With Pelvic Floor Disorders
Status: RECRUITING
Conditions: Preferred Level of Involvement in Decision Making LEP Patients
Interventions: OTHER: Physician Awareness|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of NKX019, a CD19 CAR NK Cell Therapy, in Subjects With Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: NKX019|DRUG: Cyclophosphamide LD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of Herpes Simplex Candidate Vaccine (gD2t) With Adjuvant in HSV Seropositive / Seronegative Subjects
Status: COMPLETED
Conditions: Prophylaxis for Herpes Simplex
Interventions: BIOLOGICAL: Herpes simplex candidate vaccine- adjuvanted GSK 208141|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparative Study on Three Different Doses of Intrathecal Hyperbaric Prilocaine With Fentanyl for Optimal Dose to be Used in Elderly Patients Undergoing Day Case Lower Abdominal and Urologic Surgeries.
Status: COMPLETED
Conditions: Three Different Doses of Intrathecal Hyperbaric Prilocaine With Fentanyl
Interventions: DRUG: Pilocaine 2% (1.5 ml) and 25 ug fentany
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: YSPSL for Prevention of Delayed Graft Function Part B
Status: COMPLETED
Conditions: Kidney Diseases
Interventions: DRUG: YSPSL|DRUG: placebo|DRUG: YSPSL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Validation of a New Optimized Nighttime Providence Brace for Personalized Treatment of Adolescent Idiopathic Scoliosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Scoliosis|Idiopathic Scoliosis
Interventions: DEVICE: Immediate in-brace correction: Conventional Brace|DEVICE: Immediate in-brace correction: Optimized Brace|DEVICE: Long-term bracing: Conventional Brace|DEVICE: Long-term bracing: Optimized Brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Interactive Patient-Centered Consent for Research Using Medical Records
Status: COMPLETED
Conditions: Attitude to Computers|Attitude of Health Personnel|Researcher-Subject Relations|Trust|Communication Research
Interventions: BEHAVIORAL: Trust-Enhanced Messaging on E-Consent|BEHAVIORAL: Interactive features on E-Consent|BEHAVIORAL: Standard E-Consent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Continuous Bilateral QL Analgesia After Open Abdominal Surgery
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Colorectal surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Apremilast to Treat Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: Apremilast 30 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of 21-Days Intranasal Oxytocin on Patients With Post Traumatic Stress Disorder (PTSD)
Status: UNKNOWN
Conditions: PTSD
Interventions: DRUG: Oxytoine|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lymphoscintigraphy to Detect Early Metastases in Patients With Cancer of the Mouth or Throat
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: isosulfan blue|GENETIC: polymerase chain reaction|OTHER: immunohistochemistry staining method|PROCEDURE: lymphangiography|PROCEDURE: radionuclide imaging|PROCEDURE: sentinel lymph node biopsy|RADIATION: technetium Tc 99m sulfur colloid
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Tolerability Study of FolateImmune in Combination With Cytokines in Patients With Refractory or Metastatic Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: BIOLOGICAL: EC90 (KLH-FITC)|BIOLOGICAL: GPI-0100|DRUG: EC17 (Folate-FITC)|DRUG: Interleukin-2|DRUG: Interferon-alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fast Assessment of Surfactant Deficiency in Preterm Infants to Speed up Treatment
Status: NOT_YET_RECRUITING
Conditions: Surfactant Deficiency Syndrome Neonatal|Respiratory Distress Syndrome, Newborn|Bronchopulmonary Dysplasia
Interventions: DIAGNOSTIC_TEST: LS test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial of Levator Muscle Blocks Following Posterior Colporrhaphy Surgery to Reduce Post-operative Pain.
Status: UNKNOWN
Conditions: Post Operative Pain
Interventions: DRUG: Bupivacaine|DRUG: normal saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EFFECT OF DISTRACTION METHODS ON PAIN AND ANXIETY DURING INTRAMUSCULAR INJECTION IN CHILDREN
Status: COMPLETED
Conditions: Pain, Acute|Anxiety and Fear
Interventions: DEVICE: video game playing, kaleidoscope and virtual reality glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Pharmacokinetics Study of Single Ascending Doses of VV116 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: VV116 25mg Group|DRUG: VV116 200mg Group|DRUG: VV116 400mg Group|DRUG: VV116 800mg Group|DRUG: VV116 1200mg Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Community Scabies Treatment on Head Lice Prevalence in the Solomon Islands
Status: COMPLETED
Conditions: Scabies|Head Lice
Interventions: DRUG: Ivermectin|DRUG: Permethrin 5%|DRUG: Malathion Shampoo 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of GLP-1 on Renal Hemodynamics
Status: COMPLETED
Conditions: The GLP-1-mediated Gut-kidney Axis
Interventions: DRUG: Glucagon-Like Peptide 1|DRUG: saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stress Free UC Merced: The Effect of 8 Weeks of Mindfulness App Headspace on Stress in a Sample of University Employees
Status: UNKNOWN
Conditions: Stress|Psychological Distress
Interventions: BEHAVIORAL: Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a 9 Week Exercise Programme on Fitness and Quality of Life in Rectal Cancer Patients After Chemoradiotherapy and Before Surgery
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: OTHER: Supervised exercise in hospital
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Timing of Orthodontic Therapy and Regenerative Periodontal Surgery in Advanced Periodontitis Patients With Pathologic Tooth Migration
Status: COMPLETED
Conditions: Periodontitis|Tooth Migration|Intrabony Periodontal Defect
Interventions: PROCEDURE: ParS+Ortho 4W|PROCEDURE: ParS+Ortho 6M
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cholesterol Lowering Level of MK0653A+Simvastatin in Patients With Hypercholesterolemia and Atherosclerotic or Coronary Vascular Disease (0653A-806)(COMPLETED)
Status: COMPLETED
Conditions: Hypercholesterolemia|Atherosclerotic Disease|Coronary Disease
Interventions: DRUG: MK0653A , ezetimibe (+) simvastatin|DRUG: Comparator: atorvastatin|DRUG: Duration of Treatment: 6 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Study of Leuco-methylthioninium Bis(Hydromethanesulfonate) (LMTM) in Subjects With Alzheimer's Disease or Behavioral Variant Frontotemporal Dementia (bvFTD)
Status: TERMINATED
Conditions: Alzheimer's Disease|Behavioral Variant Frontotemporal Dementia
Interventions: DRUG: LMTM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD30biAb-AATC for CD30+ Malignancies
Status: NOT_YET_RECRUITING
Conditions: Hodgkin Disease|CD30-Positive Diffuse Large B-Cell Lymphoma|CD30+ Anaplastic Large Cell Lymphoma|CD30+ Pleomorphic Large T-Cell Cutaneous Lymphoma|CD30+ Immunoblastic Large T-Cell Cutaneous Lymphoma|Leukemia|Lymphoma
Interventions: DRUG: anti-CD30 Bispecific Antibody-armed anti-CD3-Activated Autologous T-cells (CD30 biAb-AATC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label Controlled Trial: Effectiveness of Balneotherapy in Palmoplantar Psoriasis and Contact Dermatitis.
Status: COMPLETED
Conditions: Psoriasis|Contact Dermatitis of Hand
Interventions: OTHER: salt water or tap water before UVA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expressive Writing Intervention Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Distress, Emotional
Interventions: OTHER: Expressive writing in response to vignette|OTHER: Expressive writing about events of the day|OTHER: Letter of Gratitude
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Amifostine and Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Drug/Agent Toxicity by Tissue/Organ|Leukemia
Interventions: DRUG: amifostine trihydrate|DRUG: cytarabine|DRUG: idarubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Acute Medium Chain Triglycerides (MCT) Intake in Young and Older Participants
Status: COMPLETED
Conditions: Ketonemia
Interventions: DIETARY_SUPPLEMENT: No MCT intake with breakfast, no lunch|DIETARY_SUPPLEMENT: No MCT intake with lunch, no breakfast|DIETARY_SUPPLEMENT: 10g of Betaquik|DIETARY_SUPPLEMENT: 10g of Betaquik with low-carbs breakfast|DIETARY_SUPPLEMENT: 20g of Betaquik|DIETARY_SUPPLEMENT: 10g of Betaquik with lunch, no breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Music Therapy Intervention on Pain and Anxiety in Adult Patients Undergoing Total Shoulder Arthroplasty
Status: COMPLETED
Conditions: Arthritis
Interventions: OTHER: Live Music Therapy|OTHER: Recorded Music Therapy|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Sublingual Sprayable Microemulsion of Vitamin D on Inflammatory Markers in COVID-19 Patients
Status: COMPLETED
Conditions: COVID-19|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D 25 (OH) 12000 IU in the form of a sublingual sprayable microemulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Biologcal Treatment on the Short-Term Complications of Surgery in Patients With Inflematory Bowel Disease.
Status: COMPLETED
Conditions: Ulcerative Colitis|Anti TNF Therapy|Ileal Pouch Anal Anastomosis (IPAA)
Interventions: DRUG: Anti-TNF Drug
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Imvotamab in Severe Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus|Lupus Erythematosus
Interventions: DRUG: Imvotamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Early Phase Study of NEI-01 in Patients With Solid Tumors or Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumor|Relapsed AML|Refractory AML
Interventions: DRUG: NEI-01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Immunogenicity of Stabilized CH505 TF chTrimer in Healthy, HIV-uninfected Adult Participants.
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections
Interventions: BIOLOGICAL: CH505 TF chTrimer|BIOLOGICAL: 3M-05-AF|BIOLOGICAL: Aluminum hydroxide suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluating a Physician Opinion Leader Intervention to Increase Utilization of Coaching/Therapy During Residency
Status: COMPLETED
Conditions: Workplace Culture|Help-Seeking Behavior|Social Stigma|Education, Medical, Continuing
Interventions: OTHER: Popular-Opinion Leader-led encouragement during training meetings and informal conversation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Lactoferrin Versus Intravenous Iron Sucrose in Treatment of Anemia
Status: NOT_YET_RECRUITING
Conditions: Iron Deficiency Anemia
Interventions: DRUG: Intravenous iron sucrose|DRUG: Lactoferrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study on the Efficacy of Transcranial Direct Current Stimulation (tDCS) in Post-stroke Motor Recovery
Status: UNKNOWN
Conditions: Stroke, Ischemic|Stroke Hemorrhagic
Interventions: DEVICE: Anodal transcranial direct current stimulation (A-tDCS)|DEVICE: Cathodal transcranial direct current stimulation (C-tDCS)|DEVICE: Sham stimulation (sham-tDCS)|BEHAVIORAL: Neuromotor training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunoregulatory T Lymphocytes Subtypes and Haematopoietic Stem Cell Transplantation (HSCT)
Status: COMPLETED
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation for Hematological Malignancies
Interventions: BIOLOGICAL: Recipients|BIOLOGICAL: Donors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation Of Fluoride Uptake By Dentine Following Silver Diamine Fluoride Under Resin Modified Glass Ionomer Restoration In Carious Primary Molars
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: Silver diamine fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Micronized dHACM Injectable for the Treatment of Plantar Fasciitis
Status: COMPLETED
Conditions: Fasciitis, Plantar
Interventions: OTHER: Micronized dHACM|DRUG: Saline Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Avelumab With Radiotherapy in Patients With Leptomeningeal Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Leptomeningeal Metastases|Leptomeningeal Disease
Interventions: DRUG: Avelumab|RADIATION: Whole Brain Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Oxytocin Versus Tranexamic Acid in Reducing Blood Loss During Abdominal Myomectomy.
Status: COMPLETED
Conditions: Myomectomy
Interventions: DRUG: Tranexamic Acid|DRUG: oxytocin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION