pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Metal Bare Stent With 125 Iodine （125I）Seeds for the Treatment of Malignant Central Airway Stenosis
Status: UNKNOWN
Conditions: Malignant Airway Obstruction
Interventions: PROCEDURE: stent implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Permanent Internal Mammary Artery Occlusion on Extracardiac Coronary Collateral Supply
Status: COMPLETED
Conditions: Circulation, Collateral|Coronary Artery Disease|Internal Mammary-Coronary Artery Anastomosis|Ischemia
Interventions: DEVICE: Amplatzer vascular plug
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of TAF in Patients With Suboptimal Response to Other Nucleos(t)Ides
Status: UNKNOWN
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Tenofovir Alafenamide 25 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Overnight Upper Airway Infiltration in Spinal Cord Injury
Status: RECRUITING
Conditions: Obstructive Sleep Apnea|Spinal Cord Injuries
Interventions: OTHER: Pre-polysomnography mesurement|OTHER: Polysomnography measure|OTHER: Post-polysomnography measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Effect of rTMS on Attention in Adults Diagnosed With Attention-Deficit Hyperactivity Disorder (ADHD)
Status: UNKNOWN
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DEVICE: rTMS|DEVICE: shamTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Accumulative Effects of Talus Mobilization
Status: COMPLETED
Conditions: Ankle Sprains|Ankle Fractures|Ankle Dislocations|Ankle Bruises|Achilles Tendon Rupture
Interventions: OTHER: joint mobilization|OTHER: manual contact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Analysis of Lateralization of Language in Epileptic Children by Near-infrared Spectroscopy (NIRS)
Status: TERMINATED
Conditions: Epilepsy
Interventions: DEVICE: NIRS|DEVICE: fMRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Modulatory Effect of Low-intensity Priming Intermittent Theta Burst Stimulation on Motor Cortex Poststroke: a Concurrent TMS-EEG Study
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: Transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cataract on Photoentrainment of the Circadian Rhythm in Humans
Status: COMPLETED
Conditions: Cataract
Interventions: PROCEDURE: Yellow Intra Ocular Lens (IOL)|PROCEDURE: Conventional Intra Ocular Lens (IOL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nal-IRI(Nanoliposomal Irinotecan) Plus 5-FU/LV in Metastatic Biliary Tract Cancer
Status: COMPLETED
Conditions: Metastatic Biliary Tract Cancer
Interventions: DRUG: Onivyde|DRUG: 5-FU/LV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Additional Effect of Cranial Base Release on Cervical Range and Proprioception in Patients With Mechanical Neck Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Neck Pain
Interventions: PROCEDURE: Conventional Physical Therapy|PROCEDURE: Natural Apophyseal glides|PROCEDURE: Cranial Base Release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sildenafil on the Microcirculatory Blood Flow and Endothelial Progenitor Cells in Systemic Sclerosis
Status: COMPLETED
Conditions: Scleroderma, Systemic|Scleroderma, Diffuse|Scleroderma, Limited|Raynaud Phenomenon
Interventions: DRUG: Sildenafil citrate|DRUG: Placebo (Sugar pill)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relma-cel for Moderate to Severe Active Systemic Lupus Erythematosus
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Relma-cel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Use of Takepron on the Prevention of Recurrence of Gastric/Duodenal Ulcer in Patients Receiving Non-steroidal Anti-inflammatory Drugs
Status: COMPLETED
Conditions: Gastric or Duodenal Ulcers
Interventions: DRUG: Lansoprazole
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improving Mobility and Function Following Transfemoral Amputation: A Novel Approach to Reverse Volumetric Muscle Loss
Status: RECRUITING
Conditions: Traumatic Amputation of Lower Extremity
Interventions: OTHER: Ischemic Preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cannabidiol for Reduction of Brain Neuroinflammation
Status: RECRUITING
Conditions: Back Pain|Depressive Symptoms
Interventions: DRUG: CBD|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase II Trial of Sutent (Sunitinib; SU011248) for Recurrent Anaplastic Astrocytoma and Glioblastoma
Status: COMPLETED
Conditions: Anaplastic Astrocytoma|Glioblastoma
Interventions: DRUG: Sunitinib Malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery
Status: RECRUITING
Conditions: Malignant Brain Neoplasm|Malignant Glioma
Interventions: PROCEDURE: Near-Infrared Fluorescence Imaging|BIOLOGICAL: Panitumumab|DRUG: Panitumumab-IRDye800|DEVICE: POINPOINT-IR9000
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Reducing Insulin, Growth Hormones, and Tumors
Status: TERMINATED
Conditions: Diet Modification|Lung Cancer
Interventions: BEHAVIORAL: Special Diet Therapy (low-carb)|BEHAVIORAL: Special Diet Therapy (low-fat)|BEHAVIORAL: Special Diet Therapy (USDA control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fecal Microbiota Transplantation (FMT) in Treatment of Severe and Enduring Anorexia Nervosa
Status: WITHDRAWN
Conditions: Anorexia Nervosa
Interventions: BIOLOGICAL: Fecal Microbiota Transplantation (FMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Aptis PRUJ Prosthesis for the Treatment of Patients With Proximal Radial Ulna Joint Disorders.
Status: NOT_YET_RECRUITING
Conditions: Arthritis|Unstable Radial Head|Proximal Radioulnar Joint Instability|Decreased Motion at the Proximal Radioulnar Joint and/or the Radio-humeral Joint
Interventions: DEVICE: Aptis PRUJ Prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Should Colon or Non-colon Originated Lesions be Distinguished?
Status: UNKNOWN
Conditions: Acute Lower Gastrointestinal Dysfunction
Interventions: OTHER: Colon originated: Neostigmin, Colonoscopy decompression, Surgery|OTHER: Non-colon originated: Neostigmin, Colonoscopy decompression
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CXCR4 Modified Anti-BCMA CAR T Cells for Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: CXCR4 modified anti-BCMA CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefit of Allogeneic Haematopoietic Stem Cells in Cutaneous T-cell Lymphomas Epidermotropic With Advanced Stage and Poor Prognosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Epidermotropic T-cell Lymphomas
Interventions: PROCEDURE: HSCT|OTHER: Standard Care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Myoelectric Biofeedback on Upper Limb Function in Post-stroke Patients
Status: NOT_YET_RECRUITING
Conditions: Biofeedback|Rehabilitation|Cerebral Infarction
Interventions: DEVICE: Observation Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Application of 3D Visualization and 3D Printing in the Hepatobiliary and Pancreatic Surgery
Status: UNKNOWN
Conditions: Liver Diseases|Pancreatic Diseases|Biliary Tract Diseases
Interventions: OTHER: 3D visualization and 3D printing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fasting Mimicking Diet Program to ImpRovE ChemoTherapy in Hormone Receptor Postive (HR+), HER2- Breast Cancer
Status: SUSPENDED
Conditions: Fasting Mimicking Diet|HER2-negative Breast Cancer|Hormone Receptor-positive Breast Cancer|Pathological Complete Response|Objective Response Rate|Neoadjuvant Chemotherapy
Interventions: OTHER: Fasting Mimicking diet program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subgingival Clamp Versus Retraction Cord in Cervical Lesions in Term of Technique Sensitivity and Gingival Health
Status: UNKNOWN
Conditions: Gingival Retraction
Interventions: DEVICE: retraction cord|DEVICE: subgingival clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Athlete's Heart or Arrhythmogenic Right Ventricular Cardiomyopathy: Contribution of Exercise Cardiovascular Magnetic Resonance (CMR)
Status: RECRUITING
Conditions: Arrhythmogenic Right Ventricular Cardiomyopathy
Interventions: OTHER: Cardiac exercises and tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: PD1 Integrated Anti-PSMA CART in Treating Patients With Castrate-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Castrate-Resistant Prostate Cancer
Interventions: DRUG: PD1-PSMA-CART cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing New Prothesis PROPRIO-FOOT® Versus Usual Prothesis Tasks Tibial Amputees
Status: COMPLETED
Conditions: Lower Limb Amputation at Ankle (Injury)
Interventions: DEVICE: propriofoot prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of an Automated Telephone Intervention on Glycosylated Hemoglobin (HbA1c) in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: automated telephone intervention vs. usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Non-nutritive Sucking on Transition to Oral Feeding in Infants With Asphyxia
Status: COMPLETED
Conditions: Swallowing Disorder|Perinatal Asphyxia|Feeding; Difficult, Newborn|Feeding Disorder of Infancy or Early Childhood|Hypoxic-Ischemic Encephalopathy|Speech Therapy
Interventions: OTHER: Non-Nutritive Sucking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Bulk-Fill Composite Using With Adhesives With or Without Chlorhexidine
Status: ACTIVE_NOT_RECRUITING
Conditions: Class II Dental Caries
Interventions: OTHER: Class II Cavity Restorations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety APT-1011 in Adult Subjects With Eosinophilic Esophagitis (EoE) (FLUTE-2)
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: APT-1011|DRUG: Placebo oral tablet|PROCEDURE: Esophagogastroduodenoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Natriuretic Effects, Safety, Tolerability and Pharmacokinetics of BAY94-8862
Status: COMPLETED
Conditions: Clinical Pharmacology
Interventions: DRUG: Finerenone (BAY 94-8862) PEG solution|DRUG: Finerenone (BAY 94-8862) immediate release tablet|DRUG: Eplerenone (Inspra®)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Bone Marrow Derived Adult Stem Cells for Chronic Heart Failure
Status: COMPLETED
Conditions: Chronic Ischaemic Heart Failure
Interventions: DRUG: Granulocyte-colony stimulating factor|PROCEDURE: Percutaneous intracoronary injection|PROCEDURE: Percutaneous intramyocardial injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hamburg Edoxaban for Anticoagulation in COVID-19 Study
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Anticoagulation Agents (Edoxaban and/or high dose LMWH)|DRUG: Low dose Low molecular weight heparin or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study for the Validity of a Content-based Information Provision Tool Aimed at Improving the Hospitalization Experience of Liver Transplant Patients
Status: NOT_YET_RECRUITING
Conditions: Liver Transplantation|Inpatients
Interventions: OTHER: Consolidating content on a single website and providing access to it via QR codes in a brochure format
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Generic Imatinib (Carcemia®) Compared to Glivec® in Real-Life Management of Chronic Phase of Chronic Myeloid Leukemia
Status: RECRUITING
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Carcemia|DRUG: Glivec
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Epsom Salt Compresses to Relieve Perineal for Postpartum Care: A Clinical Trial
Status: RECRUITING
Conditions: Perineal Injury|Pain
Interventions: DRUG: Epsom salt|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Epidural Anesthesia on Blood Flow in Arterial Anastomosis of Free Flap
Status: COMPLETED
Conditions: Free Tissue Flaps
Interventions: OTHER: Epidural anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Zonisamide for the Treatment of Obstructive Sleep Apnea in Overweight/Obese Patients
Status: COMPLETED
Conditions: Sleep Apnea|Obstructive Sleep Apnea|Obesity
Interventions: DRUG: Zonisamide|DRUG: Placebo|DEVICE: nCPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Benefiber-Added, Reduced-Osmolarity WHO-ORS in the Treatment of Cholera in Adults
Status: COMPLETED
Conditions: Cholera
Interventions: OTHER: Benefiber|OTHER: Benefiber with ORS|OTHER: Benefiber with ORS|OTHER: Benefiber with ORS|OTHER: the reduced-osmolarity WHO-ORS without added Benefiber|OTHER: the reduced-osmolarity WHO-ORS without added Benefiber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Pulsed Inhaled Nitric Oxide vs Placebo in Subjects With Mild or Moderate COVID-19
Status: TERMINATED
Conditions: COVID-19|Coronavirus|Coronavirus Infection
Interventions: COMBINATION_PRODUCT: INOpulse|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Anxiolytic Effects of Riluzole on Subjects With Social Anxiety Disorder
Status: COMPLETED
Conditions: Social Anxiety Disorder|Performance Anxiety
Interventions: DRUG: BHV-0223|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Efficacy of Probiotics for the Treatment of Alcohol Use Disorder Among Adult Males
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DIETARY_SUPPLEMENT: Lactobacillus sp. probiotic|BEHAVIORAL: Acceptance and commitment therapy|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Zinc Sulphate vs. Zinc Amino Acid Chelate
Status: COMPLETED
Conditions: Diarrhea|Acute Respiratory Infection
Interventions: DIETARY_SUPPLEMENT: Zinc sulfate as dietary supplementation|DIETARY_SUPPLEMENT: Zinc amino acid chelate as dietary supplementation|DIETARY_SUPPLEMENT: Milk without fortification without zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Semi-inmersive Virtual Reality on Upper Limb in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Treatment Adherence|Upper Extremity Paresis
Interventions: OTHER: Conventional therapy|OTHER: semi-inversive tech
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chiropractic and Exercise for Seniors With Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: PROCEDURE: Chiropractic Manual treatment + home exercise ( procedure+behavior)|PROCEDURE: Supervised rehabilitative exercise + home exercise|BEHAVIORAL: Home exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Two Protocols for Corporal Decolonization in Patients Colonized by Methicillin Resistant Staphylococcus Aureus (MRSA)
Status: TERMINATED
Conditions: MRSA - Methicillin Resistant Staphylococcus Aureus Infection|MRSA Colonization
Interventions: DRUG: Mupirocin + Chlorhexidin|DEVICE: Prontoderm MRSA Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Program to Evaluate Riastap® and FIBTEM® for the Early Control and Treatment of Postpartum Hemorrhage (PERFECT PPH)
Status: WITHDRAWN
Conditions: Postpartum Hemorrhage
Interventions: DRUG: fibrinogen concentrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IV Interchangeability Study of a Liquid Pentavalent Combination Vaccine
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Hepatitis B|Haemophilus Influenzae Type B
Interventions: BIOLOGICAL: Shan 5|BIOLOGICAL: Easy Five
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Influence of Hyaluronic Acid on Bacillus Calmette-Guérin Local Side Effects
Status: COMPLETED
Conditions: Poisoning by BCG Vaccine
Interventions: DRUG: Hyaluronic Acid|DRUG: BCG (Immucist®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Inspiratory Muscle Training in Esophageal Resection
Status: COMPLETED
Conditions: Esophageal Resection Candidates
Interventions: OTHER: Inspiratory Muscle Training (IMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity, Safety, and Tolerability of MF59-Adjuvanted Versus Non-Adjuvanted Influenza Vaccines in Patients With HIV-1 Infection
Status: COMPLETED
Conditions: H1N1 Influenza Virus|Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Interventions: BIOLOGICAL: Focetria®|BIOLOGICAL: Begrivac®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Oral AMXT 1501 Dicaprate in Combination With IV DFMO
Status: SUSPENDED
Conditions: Cancer|Solid Tumor|Solid Carcinoma|Advanced Cancer|DIPG Brain Tumor|Ovary Cancer|Breast Cancer|Papillary Thyroid Cancer|Head and Neck Cancer|Gastric Cancer|Nsclc|Mesotheliomas Pleural|Mesothelioma Peritoneum|Esophageal Cancer|Diffuse Midline Glioma, H3 K27M-Mutant|Endometrial Cancer|Cervical Cancer|Melanoma|Colorectal Cancer|Glioma, Malignant
Interventions: DRUG: AMXT1501|DRUG: DFMO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transposition of Dynamic MRI Data From Healthy Subjects to an in Vitro Swallowing Simulator
Status: COMPLETED
Conditions: Imaging Data Collection From Dynamic Swallowing MRI in Healthy Volunteers|Create Operating Algorithms|Apply the Imaging Data of MRI to a Swallowing Simulator
Interventions: OTHER: Real-time MRI of swallowing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Assessment of a Novel Fixed-dose Combination (FDC) Drug VR-AD-1005 for the Treatment of Acute Watery Diarrhea in Cholera
Status: RECRUITING
Conditions: Cholera
Interventions: DRUG: VR-AD-1005|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Bridging Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia|Cervical Cancer|Vaginal Intraepithelial Neoplasia|Vulvar Intraepithelial Neoplasia|Persistent Infection
Interventions: PROCEDURE: 3 doses of HPV 16/18 bivalent vaccine|PROCEDURE: 2 doses of HPV 16/18 bivalent vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Emotional Support for Women Experiencing PPROM
Status: NOT_YET_RECRUITING
Conditions: Fetal Membranes, Premature Rupture|Preterm Birth Complication
Interventions: BEHAVIORAL: Psychological intervention along Cognitive Behavioural Therapy principles
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Neoplasms|Neoplasm Metastasis
Interventions: DRUG: Imlunestrant|DRUG: Exemestane|DRUG: Fulvestrant|DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Supplementation of Conjugated Linoleic Acid on Body Fat Reduction
Status: COMPLETED
Conditions: Obesity|Adiposity
Interventions: DIETARY_SUPPLEMENT: Conjugated linoleic acid group|DIETARY_SUPPLEMENT: Sunflower oil group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sarcopenia in Head and Neck Cancer Patients Treated With Curative Hadrontherapy
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: OTHER: questionnaires QLQ-FA12, Mini Nutritional Assessment Short Form, Nutritional Risk Screening, diet questionnaire of frequency, ,body mass index measurement|DIAGNOSTIC_TEST: blood biomarkers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Smoking Cessation Program in the Preadmission Clinic
Status: UNKNOWN
Conditions: Smoking
Interventions: BEHAVIORAL: Smoking counseling|DRUG: varenicline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Management of ACL Reconstruction
Status: ENROLLING_BY_INVITATION
Conditions: Anterior Cruciate Ligament Rupture
Interventions: PROCEDURE: Adductor Canal Nerve Block|DRUG: Ropivacaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intravitreal Vascular Endothelial Growth Factor Trap-eye in Patients With Polyploidal Choroidal Vasculopathy
Status: COMPLETED
Conditions: Polypoidal Choroidal Vasculopathy Without Active Polyp
Interventions: DRUG: aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nerve-Sparing Radical Prostatectomy With or Without Nerve Grafting Followed by Standard Therapy for Erectile Dysfunction in Treating Patients With Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Alprostadil (E1)|DRUG: Papaverine|DRUG: Phentolamine mesylate|DRUG: Sildenafil citrate|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Integrating Community Health Workers Into the Care of Children With Type 1 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 1 Diabetes Mellitus|Psychosocial Problem|Compliance, Patient|Diabetes Mellitus
Interventions: OTHER: Community Health Worker added to diabetes team
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sapphire 3 CTO Study
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Coronary Disease|Myocardial Ischemia|Heart Diseases|Arteriosclerosis|Cardiovascular Diseases|Chronic Total Occlusion|Chronic Total Occlusion of Coronary Artery
Interventions: DEVICE: Sapphire 3 Coronary Dilatation Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Inhaled Glucocorticosteroids/Long-Acting Bronchodilator Drugs in Subjects With Asthma That Have Been Taking Inhaled Glucocorticosteroids (Study P04705AM1)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Mometasone furoate/formoterol (MF/F) MDI|DRUG: Fluticasone propionate/salmeterol (F/SC) DPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Esophageal Protocol for Detection of Neoplasia in the Digestive Tract
Status: COMPLETED
Conditions: Barrett Esophagus|Esophageal Adenocarcinoma
Interventions: DRUG: GI heptapeptide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating Sensory-Adapted Dental Care in Children With Sensory Processing Disorders
Status: RECRUITING
Conditions: Sensory Processing Disorder
Interventions: BEHAVIORAL: Sensory-Adapted Dental Environment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparison of the I-gel and the Self-pressurised Air-Q Intubating Laryngeal Airway in Children
Status: COMPLETED
Conditions: General Anesthesia|Supraglottic Airway Devices
Interventions: DEVICE: Insertion of I-gel|DEVICE: Insertion of air-Q
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study of VESIcare® In Overactive Bladder (OAB) Subjects to Evaluate Symptom Bother and Health Related Quality of Life
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: Placebo|DRUG: Solifenacin Succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Bioavailability of Dexamethasone in Healthy Subjects
Status: COMPLETED
Conditions: Dexamethasone Administration|Intranasal Administration|Inflammation|Intravenous Drug Usage|Healthy Subjects
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Biomarkers in Predicting Response in Patients With Graft-Versus-Host Disease Undergoing Extracorporeal Photophoresis
Status: TERMINATED
Conditions: Graft Versus Host Disease (GVHD)
Interventions: PROCEDURE: extracorporeal photopheresis|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Oncaspar® + Dexamethasone in Patients With Relapsed or Refractory T-Cell Lymphoma
Status: TERMINATED
Conditions: T-Cell Lymphoma|Relapsed T-Cell Lymphoma|Refractory T-Cell Lymphoma
Interventions: DRUG: PEG-L-asparaginase|DRUG: Dexamethasone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the OsciPulse Rapid Cycling Compression Device Effects on Venous Blood Flow
Status: COMPLETED
Conditions: Venous Thromboses|Venous Stasis
Interventions: DEVICE: OsciPulse system|DEVICE: Reference Therapy 1|DEVICE: Refence Therapy 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase I Study of Safety and Pharmacokinetics of Nevirapine in HIV-1 Infected Pregnant Women and Neonates Born to HIV-1 Infected Mothers
Status: COMPLETED
Conditions: HIV Infections|Pregnancy
Interventions: DRUG: Nevirapine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Tolerability of ALTH12 Versus Mesalamine Enema in Subjects With Left-Sided Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: mesalamine|DRUG: ALTH12-1:4|DRUG: ALTH12-2:4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HAIC Combined With Adebrelimab Plus Apatinib as the First-line Treatment for HCC in BCLC Stage C: An Open-label, Single-arm, Phase II Study
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Hepatic arterial infusion chemotherapy(HAIC) combined with adebrelimab plus apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictive Ability of PEEP Induced Changes in CVP to Predict Volume Responsiveness in Mechanically Ventilated Patients After Major Abdominal Surgery
Status: UNKNOWN
Conditions: Surgery|Critical Illness|Cardiac Output, Low
Interventions: PROCEDURE: PEEP increase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Prospective Study of Outcome After Therapy for Acromegaly
Status: ACTIVE_NOT_RECRUITING
Conditions: Acromegaly
Interventions: PROCEDURE: Surgery for acromegaly|DRUG: Medications for acromegaly|DIAGNOSTIC_TEST: Total body magnetic resonance imaging|PROCEDURE: Adipose Tissue Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analysis of Chronic Neuropathic Pain Markers in Patients Treated With Oxaliplatin
Status: COMPLETED
Conditions: Digestive Cancer|Gynecological Cancer
Interventions: DEVICE: Thermotest|DEVICE: von Frey hairs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Training Physicians to Differentiate the Paris Classification Using Artificial Colon Polyp Images
Status: NOT_YET_RECRUITING
Conditions: Colonic Polyp|Colon Adenoma
Interventions: OTHER: Lutetia Training Plattform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Open, Qualitative, Prospective, Multicenter Trial of a Novel Transanal Irrigation System in Spinal Cord Injured Patients.
Status: COMPLETED
Conditions: Neurogenic Bowel
Interventions: DEVICE: Navina Smart
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: AkLief Evaluation in Acne-induced Post-Inflammatory Hyperpigmentation
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Trifarotene Cream|DRUG: Trifarotene Vehicle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Increasing Adherence to Pulmonary Rehabilitation After COPD Related Hospitalizations (Study 2)
Status: ACTIVE_NOT_RECRUITING
Conditions: COPD Exacerbation
Interventions: BEHAVIORAL: Intervention- Home-based Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of CT125A Cells for Treatment of Relapsed/Refractory CD5+ Hematopoietic Malignancies
Status: UNKNOWN
Conditions: CD5+ Relapsed/Refractory Hematopoietic Malignancies|Chronic Lymphocytic Leukemia (CLL)|Mantle Cell Lymphoma (MCL)|Diffuse Large B-cell Lymphoma (DLBCL)|Follicular Lymphoma (FL)|Peripheral T-cell Lymphomas (PTCL)
Interventions: BIOLOGICAL: CT125A cells|DRUG: Cyclophosphamide, fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Bioactive Silica Graft Plus Platelet Rich Fibrin and Only Platelet Rich Fibrin Graft in Intrabony Defects With Diabetes
Status: COMPLETED
Conditions: Intrabony Periodontal Defect
Interventions: PROCEDURE: Conventional Flap Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ticagrelor on Fractional Flow Reserve
Status: COMPLETED
Conditions: Fractional Flow Reserve
Interventions: DRUG: Ticagrelor|DRUG: Prasugrel or Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Foot Cream for the Care of Dry and Cracked Skin
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: OTHER: L-Arginin containing foot cream|OTHER: Urea-containing foot cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Diabetic Peripheral Neuropathic Pain
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: DRUG: LY3016859|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, and Formoterol Delivered by BGF MDI HFO Compared With BGF MDI HFA
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Treatment A (BGF MDI HFO with oral activated charcoal)|DRUG: Treatment B (BGF MDI HFA with oral activated charcoal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMC
Status: RECRUITING
Conditions: HIV-Associated Malignant Neoplasm|HIV Infections|Cancer|AIDS Related Lymphoma|AIDS-related Kaposi Sarcoma|AIDS-Related Malignancy|Anal Cancer|HPV-Related Malignancy
Interventions: OTHER: Non-Interventional|OTHER: Non-Interventional Follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Administration of Protein C Concentrates in Adult Critically Ill Septic Patients
Status: TERMINATED
Conditions: Sepsis
Interventions: DRUG: Protein C concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Intra-articular Injection, ENKO1, in Patients With Symptomatic Knee Osteoarthritis.
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: ENKO 1|DEVICE: Durolane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Linear Growth Study (0476-097)(COMPLETED)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: MK0476, montelukast sodium / Duration of Treatment : 56 Weeks|DRUG: Comparator : beclomethasone dipropionate / Duration of Treatment : 56 Weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Targeting Aging and Promoting Longevity With Exogenous Nucleotides (TALENTs)
Status: COMPLETED
Conditions: Aging
Interventions: DIETARY_SUPPLEMENT: dietary nucleotides|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Regional Non-comparative Prospective Study of the Impact of Gamma Knife Radiosurgery on Tremor in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DEVICE: Thalamotomy by gamma Knife radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IDA+BUCY vs BUCY Conditioning Regimen for Intermediate-risk AML Undergoing Auto-HSCT
Status: COMPLETED
Conditions: Autologous Hematopoietic Stem Cell Transplantation|Acute Myeloid Leukemia|Conditioning
Interventions: DRUG: Idarubicin（IDA）|DRUG: Busulfan (BU)|DRUG: Cyclophosphamide (CY)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mature Vinegar Prophylaxis Against Recurrent Calcium Oxalate Nephrolithiasis
Status: UNKNOWN
Conditions: Nephrolithiasis
Interventions: DIETARY_SUPPLEMENT: mature vinegar|DIETARY_SUPPLEMENT: placebo (water)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Antimicrobial Stewardship in Community Hospitals
Status: COMPLETED
Conditions: Antibiotic Stewardship in Community Hospitals
Interventions: OTHER: Antimicrobial restriction|OTHER: Post-antimicrobial prescription review
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prevention Of Sudden Cardiac Death After Myocardial Infarction by Defibrillator Implantation
Status: RECRUITING
Conditions: Sudden Cardiac Death|Myocardial Infarction
Interventions: DEVICE: Implantable cardioverter-defibrillator (ICD)|DRUG: Optimal Medical Therapy (OMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of On-Couch CBCT Image Quality
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Cancer|Thoracic Cancer|Abdominal Cancer|Pelvic Cancer
Interventions: DEVICE: HyperSight Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Investigation of Administration of MCT/ω-3 Fatty Acids is Towards Anti-inflammatory Related Fatty Acid Profile in Preterm Neonates.
Status: COMPLETED
Conditions: Premature Birth
Interventions: DIETARY_SUPPLEMENT: MCT/ω-3 fatty acids|DIETARY_SUPPLEMENT: soybean oil-based IVFE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Quetiapine Prolong, Escitalopram and Hypothalamic-pituitary-adrenocortical (HPA) Axis Activity in Depressed Patients
Status: COMPLETED
Conditions: Major Depression
Interventions: DRUG: quetiapine|DRUG: escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double-blinded, Placebo-controlled, Evaluating the Treatment With LB-102 in Patients With Acute Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: LB-102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Evaluating Maintenance Chemotherapy for Metastatic Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Conventional chemotherapy|DRUG: Maintenance chemotherapy 1|DRUG: Maintenance chemotherapy 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Assessment of Azyter® Eye Drops (T1225) in Patients With Blepharitis
Status: COMPLETED
Conditions: Blepharitis
Interventions: DRUG: Azithromycin|DRUG: Povidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Egito Association in the Treatment of Type II Diabetes Mellitus and Hypertension
Status: WITHDRAWN
Conditions: Hypertension Associated|Type II Diabetes Mellitus
Interventions: DRUG: Egito|DRUG: Empagliflozin + telmisartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of Novel MSLN CAR-T Cell Therapy in Patients With MSLN-positive Advanced Refractory Solid Tumors
Status: WITHDRAWN
Conditions: Mesothelin-positive Advanced Refractory Solid Tumors
Interventions: BIOLOGICAL: Anti-mesothelin CAR-T cells|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 10-week Study Evaluating the Efficacy and Safety of PD 0332334 in Patients With Generalized Anxiety Disorder (1)
Status: TERMINATED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: PD 0332334|DRUG: PD 0332334|DRUG: PD 0332334|DRUG: Paroxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SBRT Sequential CapeOX Regimen Combined With Bevacizumab and Sintilimab in First-line Treatment of mCRC
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: COMBINATION_PRODUCT: SBRT Sequential CapeOX Regimen Combined With Bevacizumab and Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Education for Activity and Nutrition for a Leaner You
Status: COMPLETED
Conditions: Body Weight Changes|Overweight
Interventions: BEHAVIORAL: Group weight loss program|OTHER: Group weight loss program plus use of the Senseware Armband|DEVICE: Use of the senseware armband alone program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Does Whole Blood Adsorber During CPB Reduce Vasoactive Drugs Postoperatively in Endocarditis Patients Undergoing Valve Surgery?
Status: COMPLETED
Conditions: Infective Endocarditis
Interventions: DEVICE: CytoSorb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE