pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Learn About the Study Medicine (Called Ritlecitinib) For the Potential Treatment of Severe Alopecia Areata (AA) In Children 6 To Less Than 12 Years of Age
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: Ritlecitinib 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Chemotherapy Combined With Apatinib and PD-1 Antibody
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: PD-1 antibody, paclitaxel or irinotecan, Apatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bowman-Birk Inhibitor Concentrate in Preventing Cancer in Healthy Men
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: OTHER: placebo|DRUG: Bowman-Birk inhibitor concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Colloid Versus Crystalloid on Coagulation in Elective Urological Surgery
Status: COMPLETED
Conditions: Disorders of Coagulation
Interventions: DRUG: Lactated Ringer|DRUG: Hydroxyethylstarch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Single Incision Laparoscopic Colorectal Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Laparoscopic Colorectal Surgery
Interventions: PROCEDURE: single incision laparoscopic surgery|PROCEDURE: conventional laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Best Parameters for Imaging Agent Injection and Scanning Methods in Computed Tomography Angiography
Status: COMPLETED
Conditions: Enhancement of Aorta and Pulmonary Artery|Radiation Exposure
Interventions: DIAGNOSTIC_TEST: Different contrast media injection methods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Physiologic and Functional Adaptations of Insulin Sensitive Tissues
Status: ENROLLING_BY_INVITATION
Conditions: Diabetes|Insulin Resistance|Obesity|Bariatric Surgery Candidate|Roux-en-y Gastric Bypass|Liver Diseases
Interventions: OTHER: Endoscopy biopsy|OTHER: Surgical biopsy|OTHER: Mixed-meal tolerance test|OTHER: Excised Liver Tissue Sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low Frequency TMS on DLPFC and OFC in OCD Patients
Status: COMPLETED
Conditions: Psychiatric Disorder
Interventions: PROCEDURE: Repetitive trans-magnetic stimulation (rTMS) on DLPFC|PROCEDURE: Repetitive trans-magnetic stimulation (rTMS) on OFC|PROCEDURE: Sham repetitive trans-magnetic stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cone Beam CT Guided Electromagnetic Navigational Bronchoscopy
Status: COMPLETED
Conditions: Lung Nodule|Lung Mass|Lesion of the Lung
Interventions: PROCEDURE: Cone Beam CT with Embo Guide to creat 3D Overlay and CT Augmented Fluoroscopy to guide Electromagnetic Navigational Bronchoscopy instead of Standard Fluroscopic guidance using the C-Arm
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating Efficacy and Safety of 1-year of DAPT After Genoss DES Sirolimus-eluting Stent Implantation in Patients
Status: RECRUITING
Conditions: Coronary Artery Disease|Percutaneous Coronary Intervention|Dual Antiplatelet Therapy
Interventions: DEVICE: Genoss DES stent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Adjunctive Ganaxolone Treatment in Children and Young Adults With CDKL5 Deficiency Disorder
Status: COMPLETED
Conditions: CDKL5 Deficiency Disorder
Interventions: DRUG: ganaxolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of CP-751,871 In Combination With Sunitinib In Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced Cancer|Advanced Solid Tumors
Interventions: DRUG: CP-751,871|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patients Undergoing Laparoscopic Colorectal Surgery Walk Out From Operating Room After Surgery ( WOFOR-C1 )
Status: RECRUITING
Conditions: Enhanced Recovery After Surgery
Interventions: BEHAVIORAL: walk out from operating room
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Escitalopram Versus Placebo in the Treatment of Depressive Syndrome in Alzheimer's Disease, Vascular Dementia, and Mixed Vascular and Alzheimer's Dementia
Status: UNKNOWN
Conditions: Depressive Syndrome
Interventions: DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Intracorporeal Anastomosis in Laparoscopic Left Colectomy. Cohort Comparative Study
Status: UNKNOWN
Conditions: Colon Cancer
Interventions: PROCEDURE: Extracorporeal left hemicolectomy anastomosis|PROCEDURE: Intracorporeal left hemicolectomy anastomosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Hypopressive Breathing and Noble Technique on DRA in Postpartum Women.
Status: COMPLETED
Conditions: Diastasis Recti Abdominis
Interventions: OTHER: hypopressive breathing|OTHER: noble technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Wide Spectrum Micronutrients Supplementation in Patients With Cancer Related Fatigue During Adjuvant Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Fatigue|Breast Cancer
Interventions: DIETARY_SUPPLEMENT: APPOPRTAL®|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Supporting Young Women's Reproductive Health by Harnessing Prosociality Among Drug Shopkeepers
Status: RECRUITING
Conditions: Hiv|Contraception
Interventions: BEHAVIORAL: Harnessing prosocial and social image motivations for behavior change
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Esomeprazole In Patients With Gastric Acid Hypersecretory States Including Idiopathic Hypersecretion and Zollinger-Ellison Syndrome
Status: COMPLETED
Conditions: Zollinger-Ellison Syndrome
Interventions: DRUG: Esomeprazole magnesium (Nexium)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Botulinum Toxin A in Preventing Scar Formation and Initial Exploration of "Optimal Concentration"
Status: ACTIVE_NOT_RECRUITING
Conditions: Scar
Interventions: DRUG: Botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The BCI 602 BONEBRIDGE Post-Market Clinical Follow-up Study
Status: COMPLETED
Conditions: Hearing Loss|Hearing Loss, Conductive|Hearing Loss, Mixed|Hearing Loss, Unilateral|Hearing Loss, Bilateral|Hearing Loss, Sensorineural
Interventions: DEVICE: Bone Conduction Implant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Development of the Wearable Arm Volume Measurement Device and Mobile Application
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer Related Lymphedema
Interventions: DEVICE: Mobile application and an arm volume measurement device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Development of a Model to Predict Progression-Free Survival After Erlotinib in Patients With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: GENETIC: gene mapping|GENETIC: polymorphism analysis|OTHER: diagnostic laboratory biomarker analysis|OTHER: immunohistochemistry staining method
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Dynamic Fluid Responsiveness by EIT and Transpulmonary Thermodilution in Postoperative of CABG Patients
Status: UNKNOWN
Conditions: Coronary Artery Bypass Grafting|Fluid Therapy|Stroke Volume|Hemodynamic Monitoring
Interventions: DIAGNOSTIC_TEST: Passive Leg Raising (PLR) and PEEP increment (PEEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Wound Problems Wound Dressing in Patients With Colorectal Cancer Surgery
Status: COMPLETED
Conditions: Colorectal Cancer|Surgery|Surgery--Complications|Surgical Site Infection|Wound Complication
Interventions: DEVICE: pNBYT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Dexamethasone on Pain After Total Knee Replacement Surgery
Status: TERMINATED
Conditions: Arthroplasty, Knee Replacement|Pain, Postoperative
Interventions: DRUG: Dexamethasone|DRUG: Sodium Chloride, (24)NaCl 0,9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxytocin vs Prostaglandins for Labor Induction of Women With an Unfavorable Cervix After 24h of Cervical Ripening
Status: RECRUITING
Conditions: Cervical Ripening|Unfavorable Cervix
Interventions: DRUG: Prostaglandins|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial on the Efficacy of Prontosan Wound Irrigation Solution and Prontosan Wound Gel
Status: COMPLETED
Conditions: Venous Leg Ulcer
Interventions: DEVICE: Prontosan Wound Irrigation Solution and Prontosan Wound Gel|DEVICE: Normal Saline and Placebo Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treprostinil Therapy For Patients With Interstitial Lung Disease And Severe Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension|Interstitial Lung Disease|Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Treprostinil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of DRM02 in Subjects With Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: DRM02|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrscalene Block Versus Pericapsular Nerve Group Block for Arthroscopic Shoulder Surgery
Status: RECRUITING
Conditions: Rotator Cuff|Bankert Repair
Interventions: DIAGNOSTIC_TEST: Interscalene versus PENG Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Heterologous Prime-boost Study to Evaluate Immunogenicity and Safety of mRNA-1273 With MVC-COV1901 in Adults
Status: COMPLETED
Conditions: Covid19 Vaccine
Interventions: BIOLOGICAL: Homologous boost schedule|BIOLOGICAL: Heterologous boost schedule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparative Study Between Lysine Clonixinate+Cyclobenzaprine and Caffeine+Carisoprodol+Sodium Diclofenac+Paracetamol
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: DRUG: Tandrilax|DRUG: Dolamin Flex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Robot-assisted vs. Open Nipple-sparing Mastectomy With Immediate Breast Reconstruction
Status: RECRUITING
Conditions: Breast Cancer Patients in Stage 0-3A in Preoperative Evaluation
Interventions: PROCEDURE: robot assisted nipple sparing mastectomy(RNSM)|PROCEDURE: Conventional nipple sparing mastectomy(CNSM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Esophageal Dysfunction Associated With Opioids: Clinical Response and Manometric Findings After Opioid Discontinuation
Status: RECRUITING
Conditions: Opioid Use
Interventions: DRUG: The intervention involves the discontinuation of the opioid.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comprehensive HIV Prevention Package for MSM in Port Elizabeth
Status: COMPLETED
Conditions: HIV
Interventions: BEHAVIORAL: Condom choices|BEHAVIORAL: Condom-compatible lubricant choices|BEHAVIORAL: Couples HIV counseling and testing (CVCT)|DRUG: Emtricitabine/Tenofovir Disoproxil Fumarate (FTC/TDF)|OTHER: HIV Testing|OTHER: Linkage to care|PROCEDURE: Post-exposure prophylaxis (PEP)|BEHAVIORAL: Risk-reduction counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies
Status: RECRUITING
Conditions: Acute Leukemia|Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Adult Diffuse Large Cell Lymphoma|Anaplastic Large Cell Lymphoma|Burkitt Lymphoma|Chronic Myeloid Leukemia, BCR-ABL1 Positive|Chronic Myelomonocytic Leukemia|Hodgkin Lymphoma|Lymphoblastic Lymphoma|Lymphoplasmacytic Lymphoma|Mantle Cell Lymphoma|Mixed Phenotype Acute Leukemia|Myelodysplastic Syndrome|Prolymphocytic Leukemia|Refractory Chronic Lymphocytic Leukemia|Refractory Follicular Lymphoma|Refractory Marginal Zone Lymphoma|Refractory Small Lymphocytic Lymphoma
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Cyclophosphamide|DRUG: Cyclosporine|BIOLOGICAL: Filgrastim|DRUG: Fludarabine|DRUG: Mycophenolate Mofetil|DRUG: Mycophenolate Sodium|RADIATION: Total-Body Irradiation|DRUG: Treosulfan|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Echocardiography|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Idelalisib (GS1101, CAL101) + Ofatumumab in Previously Untreated CLL/SLL
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Idelalisib|DRUG: Ofatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy and Interleukin-12 With Either Alum or Sargramostim After Surgery in Treating Patients With Melanoma
Status: COMPLETED
Conditions: Intraocular Melanoma|Melanoma (Skin)
Interventions: BIOLOGICAL: MART-1 antigen|BIOLOGICAL: gp100 antigen|BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: recombinant interleukin-12|BIOLOGICAL: sargramostim|BIOLOGICAL: tyrosinase peptide|DRUG: alum adjuvant|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin Evaluation on Atrial Fibrillation Patients Followed Cox Maze IV Procedure
Status: RECRUITING
Conditions: Atrial Fibrillation Recurrence|Cox Maze IV|Atrial Fibrillation|Patients With or Without Heart Failure and Diabetes
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Recovery of Ventilation After Anesthesia for Laparoscopic Nephrectomy
Status: COMPLETED
Conditions: Ventilatory Depression|Postoperative Respiratory Complication
Interventions: OTHER: Oxygen gas -Conservative|OTHER: Oxygen gas -Liberal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effects of Epicatechin-rich Cocoa on Collagen Synthesis
Status: COMPLETED
Conditions: Collagen Synthesis
Interventions: OTHER: Epicatechin-rich cocoa dose response|OTHER: Epicatechin-rich cocoa vs placebo on performance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Labor Induction After Failed Induction With Dinoprostone.
Status: COMPLETED
Conditions: Induction of Labor Affected Fetus / Newborn
Interventions: DRUG: Dinoprostone|DEVICE: Cervical ripening balloon.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Impact of Maintaining Hemoglobin Levels Using Epoetin Alfa in Patients With Metastatic Breast Cancer Receiving Chemotherapy
Status: COMPLETED
Conditions: Anemia|Breast Neoplasms|Quality of Life
Interventions: DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Treatment Of Steroid-Refractory Acute Graft-versus-host Disease With Mesenchymal Stromal Cells Versus Best Available Therapy
Status: RECRUITING
Conditions: Steroid-refractory Acute Graft-versus-host Disease
Interventions: BIOLOGICAL: MC0518|BIOLOGICAL: BAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve)
Status: WITHDRAWN
Conditions: Thymidine Kinase 2 Deficiency
Interventions: DRUG: MT1621
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ASKB589 in Combination With CAPOX and PD-1 Inhibitor in Patients With Advanced or Metastatic GC/GEJ Adenocarcinoma
Status: RECRUITING
Conditions: Gastroesophageal Junction Adenocarcinoma|Gastric Adenocarcinoma
Interventions: DRUG: ASKB589|DRUG: Oxaliplatin|DRUG: Capecitabine|DRUG: Tislelizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sodium Alginate on Appetite Sensation
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DIETARY_SUPPLEMENT: Alginate|DIETARY_SUPPLEMENT: Alginate|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Child Protective Outcomes Among Ultra-poor Families in Burkina Faso
Status: COMPLETED
Conditions: Child Abuse|Child Maltreatment
Interventions: BEHAVIORAL: Trickle Up|BEHAVIORAL: Trickle Up Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stem Cells and Stromal Vascular Fraction for Temporomandibular Joint Disease
Status: UNKNOWN
Conditions: Temporomandibular Joint Disorders|Temporomandibular Disorder|Temporomandibular Joint Osteoarthritis|Temporomandibular Joint Pain|Temporomandibular Joint Effusion
Interventions: BIOLOGICAL: Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-PD-1 and CapOx for the First-line Treatment of dMMR Esophagogastric Cancer (AuspiCiOus)
Status: RECRUITING
Conditions: Gastric Adenocarcinoma|Esophageal Adenocarcinoma
Interventions: DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Retifanlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cocaine Opioid Oxytocin Option - Limited
Status: COMPLETED
Conditions: Opioid Use Disorder|Cocaine Use Disorder
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients
Status: RECRUITING
Conditions: Psoriatic Arthritis
Interventions: DRUG: Guselkumab|DRUG: Golimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Nasal and Forehead Oximetry in Critically Ill Patients at Risk for Decreased Peripheral Perfusion
Status: COMPLETED
Conditions: Hypotension|Pressure Ulcer
Interventions: DEVICE: Nasal alar oxygen sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study To Understand Fall Reduction and Vitamin D in You
Status: TERMINATED
Conditions: Vitamin D Deficiency|Falls
Interventions: DIETARY_SUPPLEMENT: 200 IU/d cholecalciferol|DIETARY_SUPPLEMENT: 1000 IU/d cholecalciferol|DIETARY_SUPPLEMENT: 2000 IU/d cholecalciferol|DIETARY_SUPPLEMENT: 4000 IU/d cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: First-in-Human Dose Escalation Study of XMT-1536 in Cancers Likely to Express NaPi2b
Status: COMPLETED
Conditions: Platinum Resistant Ovarian Cancer|Non Small Cell Lung Cancer Metastatic
Interventions: DRUG: upifitamab rilsodotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of SAR125844 Single Agent Administered as Slow Intravenous Infusion in Adult Patients With Advanced Malignant Solid Tumors
Status: COMPLETED
Conditions: Malignant Solid Tumors
Interventions: DRUG: SAR125844
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder
Status: RECRUITING
Conditions: Opioid Use Disorder
Interventions: DRUG: Sublingual buprenorphine with naloxone|DRUG: Injectable subcutaneous buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Postoperative Radiotherapy and Concurrent Chemotherapy Effectiveness in Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer|Toxicity Due to Radiotherapy
Interventions: RADIATION: Radiation|DRUG: cisplatin（DDP） weekly|DRUG: docetaxel plus cisplatin|DRUG: docetaxel plus cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Bowel Preparation Using 2 Liter Polyethylene Glycol Regimen Plus Elobixibat Versus 4-Liter Polyethylene Glycol Regimen
Status: RECRUITING
Conditions: Bowel Preparation Solution|Colonoscopy
Interventions: DRUG: 2-Liter polyethylene glycol plus elobixibat|DRUG: 4-Liter polyethylene glycol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Melatonin as a Circadian Clock Regulator, Neuromodulator and Myelo-protector in Adjuvant Breast Cancer Chemotherapy
Status: COMPLETED
Conditions: Sleep Disorders, Circadian Rhythm|Depression|Genotoxicity|Pain
Interventions: DRUG: Melatonin 20 MG Oral Capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ending Sexual Harassment - Teaching Of Principal Investigators
Status: ENROLLING_BY_INVITATION
Conditions: Sexual Harassment
Interventions: BEHAVIORAL: E-STOP online educational program (treatment condition)|BEHAVIORAL: E-STOP online educational program (control condition)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: R&D Supporting Pilot Study for the Assessment of the Safety and Effectiveness of the ProVATE (ProTIPI) Vaginal Pessary
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse
Interventions: DEVICE: ProVATE vaginal pessary
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azathioprine Based on Endoscopy After Clinical Remission in Moderate to Severe Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: Azathioprine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Mirikizumab in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Mirikizumab Prefilled Syringe|DRUG: Mirikizumab Autoinjector
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Implantation of Endobronchial Valves Versus Intrabronchial Valves in Patients With Severe Heterogeneous Emphysema
Status: COMPLETED
Conditions: Pulmonary Emphysema
Interventions: DEVICE: EBV implantation|DEVICE: IBV implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dendritic Cell Vaccination to Prevent Hepatocellular Carcinoma Recurrence After Liver Resection-phase II Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: Autologous Dendritic Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Mydriatic Eye Drops in Retinopathy of Prematurity Examinations
Status: COMPLETED
Conditions: Retinopathy of Prematurity|Mydriasis|Neonatal Disease|Analgesic Adverse Reaction
Interventions: DEVICE: NIRS(INVOS 5100; Covidien Somanetics, Troy, MI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acarbose and Older Adults With Postprandial Hypotension
Status: COMPLETED
Conditions: Other Specified Hypotension|Syncope
Interventions: DRUG: Acarbose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ondansetron's Opposite Effect on Postoperative Analgesia of Acetaminophen
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: ondansetron|DRUG: isotonic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Micronutrient Supplementation and Fish Oil + Micronutrient Supplementation in the Treatment of Environmental Enteropathy
Status: COMPLETED
Conditions: Environmental Enteropathy
Interventions: DIETARY_SUPPLEMENT: Fish oil and Micronutrient Supplementation|DIETARY_SUPPLEMENT: Micronutrient Supplement|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Elbasvir/Grazoprevir Fixed-Dose Combination for 8 Weeks in G1b Treatment-Naïve, HCV-Infected Patients
Status: COMPLETED
Conditions: Chronic HCV Hepatitis
Interventions: DRUG: Elbasvir 50 MG / Grazoprevir 100 MG Oral Tablet [Zepatier]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic-assisted Total Gastrectomy Versus Open Total Gastrectomy With Splenic Hilum Lymph Nodes Dissection
Status: UNKNOWN
Conditions: Gastric Cancer|Splenic Hilum Lymph Nodes Dissection|Total Gastrectomy
Interventions: PROCEDURE: Laparoscopic-assisted total gastrectomy|PROCEDURE: Open total gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoluminale Obliteration Der Stammvene Mit Dem 1470nm Laser Versus VNUS Closure Fast
Status: UNKNOWN
Conditions: Venous Insufficiency
Interventions: PROCEDURE: Laser|PROCEDURE: Radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Penetrating the Classroom Social Network for Children With Language Impairment Via Peer Mediated Intervention
Status: COMPLETED
Conditions: Peer Influence
Interventions: BEHAVIORAL: Peer-mediated pivotal response training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting the Gut-brain Axis to Facilitate Weight Loss in High Fat Diet Consumers
Status: ACTIVE_NOT_RECRUITING
Conditions: Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: RiduZone (90% OEA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Placebo Controlled Efficacy and Safety Study of CD2475/101 40 mg Tablets vs. Placebo and Doxycycline 100 mg Capsules Once Daily in the Treatment of Inflammatory Lesions of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: CD2475/101 40 mg|DRUG: Doxycycline 100 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Too Much of a Good Thing? Impact of Initial Prescription Size in Post-cesarean Section Pain Management
Status: UNKNOWN
Conditions: Post Operative Pain
Interventions: DRUG: Oxycodone oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Nevirapine Compared to ZDV + 3TC Administered in Labor and Again at Postdelivery in HIV Positive Women
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nevirapine|DRUG: Zidovudine (ZDV)|DRUG: Lamivudine (3TC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Human Central Nervous System Stem Cells (HuCNS-SC) in Patients With Thoracic Spinal Cord Injury
Status: COMPLETED
Conditions: Thoracic Spinal Cord Injury|Spinal Cord Injury|Spinal Cord Injury Thoracic|Spinal Cord Trauma
Interventions: BIOLOGICAL: HuCNS-SC cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Needle-free Disposable-syringe Jet Injector (DSJI) ID Dose-sparing of Pandemic A H1N1 Influenza Vaccine
Status: UNKNOWN
Conditions: Influenza
Interventions: BIOLOGICAL: 2012 trivalent influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Brief Behavioral Therapy in Improving Sleep Disorders in Patients With Stage I-III Breast Cancer Undergoing Chemotherapy
Status: COMPLETED
Conditions: Sleep Disorder|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: BEHAVIORAL: Brief Behavioral Therapy|BEHAVIORAL: Telephone-Based Intervention|OTHER: Educational Intervention|BEHAVIORAL: Telephone-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing Ticagrelor Versus Clopidogrel on Microcirculation
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feedback in the Consultation - a Dialogue-based Tool in Personalised Care Planning Using Systematic Patient Involvement
Status: COMPLETED
Conditions: Melanoma|Quality of Life
Interventions: BEHAVIORAL: Feedback in the consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Akt Inhibitor MK2206 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer
Status: COMPLETED
Conditions: Recurrent Squamous Cell Carcinoma of the Nasopharynx|Stage IV Squamous Cell Carcinoma of the Nasopharynx
Interventions: DRUG: Akt inhibitor MK2206
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety of Shortened Infusion Times for dIfferent Oncological Immunotherapie
Status: RECRUITING
Conditions: Oncology|Infusion Reaction
Interventions: DRUG: Nivolumab|DRUG: Pembrolizumab|DRUG: Ipilimumab|DRUG: Durvalumab|DRUG: Atezolizumab|DRUG: Bevacizumab|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Acute Effect of Cycling Practice in Lumbar and Thigh Muscles
Status: COMPLETED
Conditions: Physical Endurance|Muscle Fatigue|Musculoskeletal Pain|Muscle Tightness
Interventions: OTHER: 3 hours Road Cycling Time Trial|OTHER: 3 hours Mountain Biking Time Trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Remote Asthma Management Using an Integrated Artificial Intelligence-assisted EHR Dashboard and Mobile Device Compared With Usual Asthma Care to Treat 6-17 Year Old Patients
Status: ENROLLING_BY_INVITATION
Conditions: Asthma in Children
Interventions: DEVICE: AsthmaTuner|OTHER: Asthma-Guidance and Prediction System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of All-trans Retinoic Acid With Chemotherapy Based on Paclitaxel and Cisplatin As First-line Treatment of Patients With Advanced Non-small Cell Lung Cancer and Expression of RAR-alfa and RAR-beta as Response Biomarker
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: atRA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Called FINE-REAL to Learn More About the Use of the Drug Finerenone in a Routine Medical Care Setting
Status: RECRUITING
Conditions: Chronic Kidney Disease|Type 2 Diabetes Mellitus
Interventions: DRUG: Kerendia (Finerenone, BAY94-8862)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I Multicenter Clinical Trial to Evaluate the Safety and Immunogenicity of Immuno-AG Recombinant HIV gp160 in Asymptomatic HIV Seropositive Individuals
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: gp160 Vaccine (Immuno-AG)|BIOLOGICAL: Hepatitis B Vaccine (Recombinant)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of SH-1028 Tablets Versus Gefitinib in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: SH-1028 tablets|DRUG: Placebo SH-1028 tablets|DRUG: Gefitinib|DRUG: Placebo Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Culturally Sensitive Cognitive Behavioural Therapy for the Survivors of Intimate Partner Violence (IPV)
Status: COMPLETED
Conditions: Mental Abuse of Adult|Emotional Abuse|Domestic Violence
Interventions: OTHER: CS-CBT|OTHER: CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SMET12 and Toripalimab Combined Chemotherapy in Patients With EGFR Positive Advanced Non-small Cell Lung Cancer (NSCLC)
Status: NOT_YET_RECRUITING
Conditions: EGFR Positive Non-small Cell Lung Cancer
Interventions: DRUG: SMET12|DRUG: SMET12|DRUG: SMET12
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Placebo and an Active Comparator in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis|Moderate to Severe Chronic Plaque Psoriasis|Psoriatic Arthritis
Interventions: DRUG: Bimekizumab|DRUG: Ustekinumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treat Autosomal Dominant Polycystic Kidney Disease With Oral Ketone Ester?
Status: NOT_YET_RECRUITING
Conditions: ADPKD
Interventions: DIETARY_SUPPLEMENT: Ketone ester
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study For Patients With NSCLC EGFR Mutations (Del 19 or L858R +/- T790M)
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: PF-06747775|DRUG: Palbociclib|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impacts of Mitochondrial-targeted Antioxidant on Peripheral Artery Disease Patients
Status: RECRUITING
Conditions: Peripheral Arterial Disease|Peripheral Artery Disease
Interventions: DIETARY_SUPPLEMENT: MitoQ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency of GDS Method for Lumbar Stabilization for Non-Specific Low Back Pain in Primary Care
Status: COMPLETED
Conditions: Low Back Pain
Interventions: BEHAVIORAL: GDS Method (muscular chains physical therapy method)|BEHAVIORAL: Conventional Physical Therapy in Primary Health Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Inspiratory Muscle Training and Respiratory Physiotherapy on Pulmonary Functions, Respiratory Muscle Strength and Functional Capacity in Patients With Robotic Heart Surgery
Status: COMPLETED
Conditions: Robotic Surgical Procedures|Heart Diseases
Interventions: OTHER: Standard respiratory physiotherapy|OTHER: Standard respiratory physiotherapy and inspiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Spencer's Muscle Energy Technique and Post-facilitation Stretch in Patients With Adhesive Capsulitis
Status: COMPLETED
Conditions: Frozen Shoulder
Interventions: OTHER: Spencer's MET with conventional therapy|OTHER: Post-Facilitation Stretch with conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of a Minor Ailment Service in Community Pharmacy Practice
Status: COMPLETED
Conditions: Acne|Bites|Burns|Cold|Cold Sore Mouth|Constipation|Cough|Dental Trauma|Dermatitis|Diarrhea|Dry Eye|Dysmenorrhea|Flatulence|Foot Fungal Infection|Hemorrhoids|Headache|Heartburn|Hyperhidrosis|Mouth Ulcer|Musculoskeletal Pain|Nasal Congestion|Rash|Red Eye|Sleep Disorder|Soft Tissue Injuries|Sore Throat|Stress Disorder, Acute|Temperature Regulation Disorder|Vaginal Candidiasis|Varicose Veins|Vomiting
Interventions: OTHER: Minor ailment service
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097, Paclitaxel, and Carboplatin Before Surgery in Treating Patients With Stage II or Stage III Triple-Negative Breast Cancer
Status: TERMINATED
Conditions: Estrogen Receptor Negative|HER2/Neu Negative|Progesterone Receptor Negative|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Triple-Negative Breast Carcinoma
Interventions: DRUG: Carboplatin|DRUG: Gamma-Secretase Inhibitor RO4929097|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|OTHER: Pharmacological Study|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Celecoxib in Decreasing the Damaging Effects of Sunburn in Healthy Volunteers
Status: COMPLETED
Conditions: No Evidence of Disease
Interventions: DRUG: Celecoxib|OTHER: Laboratory Biomarker Analysis|PROCEDURE: UV Light Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Impact of Pre-emptive Home Delivery of ORS + Zinc on Treatment for Child Diarrhea
Status: NOT_YET_RECRUITING
Conditions: Diarrhea Toddler
Interventions: BEHAVIORAL: Community Sensitization + Household visit + Information + Free pre-emptive distribution of ORS+Zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Circadian Variations of Prostaglandin in Sleep Apnea
Status: COMPLETED
Conditions: Sleep Apnea|Continuous Positive Airway Pressure|Prostaglandins|Circadian Variations
Interventions: DEVICE: CPAP treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lintuzumab (SGN-33) in Combination With Low Dose Cytarabine in Patients 60+ Years With AML
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Lintuzumab (SGN-33)|DRUG: Low dose cytarabine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Whole-body Vibration Without Visual Feedback on Postural Steadiness in Unilateral Trans-femoral Traumatic Amputees
Status: COMPLETED
Conditions: Amputation; Traumatic, Leg, Lower
Interventions: DEVICE: Whole-body vibration plus conservative care|OTHER: conservative care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Second Infusion (Early Reinfusion) of Tisagenlecleucel in Children and Young Adults With B-Cell Acute Lymphoblastic Leukemia(B-ALL)
Status: RECRUITING
Conditions: B-cell Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: Tisagenlecleucel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TRARO (Traumeel® S in Rotator Cuff Syndrome)-Study
Status: COMPLETED
Conditions: Rotator Cuff Syndrome|Shoulder Bursitis
Interventions: DRUG: Traumeel S inj|DRUG: Fortecortin/Dexamethasone 8 mg/2 ml inj|DRUG: Saline inj
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zemaira in Subjects With Emphysema Due to Alpha1-Proteinase Inhibitor Deficiency
Status: COMPLETED
Conditions: Alpha1-proteinase Inhibitor Deficiency|Emphysema
Interventions: BIOLOGICAL: Alpha1-proteinase inhibitor|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Implanted Microstimulators for Decreasing Spasticity and Improving Motion Following Spinal Cord Injury
Status: TERMINATED
Conditions: Spinal Cord Injury at C5-C7 Level With Incomplete Lesion
Interventions: DEVICE: Radio Frequency Microstimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Saffron on Mild to Moderate Generalized Anxiety Disorder (GAD)
Status: UNKNOWN
Conditions: Patients With Mild to Moderate GAD
Interventions: DIETARY_SUPPLEMENT: Saffron|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT