pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Prophylactic Treatment of Hepatic Dysplastic Nodules in HBsAg Positive Patients
Status: UNKNOWN
Conditions: Dysplastic Nodule of Liver|Chronic Hepatitis B
Interventions: PROCEDURE: minimally invasive ablation therapies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nanofat Versus Platelet Poor Plasma Gel for Infraorbital Rejuvenation
Status: COMPLETED
Conditions: Tear Trough Eyelid Deformity
Interventions: BIOLOGICAL: platelet poor plasma gel|BIOLOGICAL: nanofat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Short-term Compression Therapy After Thermal Ablation for Varicose Veins
Status: RECRUITING
Conditions: Varicose Veins
Interventions: DEVICE: elastic bandage|DEVICE: compression stocking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aramchol for HIV-associated Nonalcoholic Fatty Liver Disease and Lipodystrophy
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver Disease|HIV
Interventions: DRUG: Aramchol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Liposomal Doxorubicin in Treating Women With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: pegylated liposomal doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Perioperative Intravenous Fluid Utilization on Postoperative Outcomes
Status: COMPLETED
Conditions: Benign Neoplasm of Intestinal Tract|Primary Malignant Neoplasm of Intestinal Tract|Secondary Malignant Neoplasm of Intestinal Tract
Interventions: PROCEDURE: Normal fluid volume|PROCEDURE: Reduced fluid volume
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Using Clinical Guidelines on Kangaroo Care on Newborn and Maternal Outcomes
Status: COMPLETED
Conditions: Premature Infants
Interventions: OTHER: Kangaroo care based on kangaroo care guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized, Open-label, Multi-center, Phase III Study of Orelabrutinib in Combination With Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) vs. R-CHOP Alone in Patients With Treatment-naїve Mantle Cell Lymphoma
Status: RECRUITING
Conditions: Treatment-naїve Mantle Cell Lymphoma
Interventions: DRUG: Orelabrutinib and R-CHOP|DRUG: R-CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COmbination Therapy With Baloxavir and Oseltamivir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)
Status: RECRUITING
Conditions: Influenza
Interventions: DRUG: Baloxavir|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of AZD4547 in Combination With Fulvestrant vs. Fulvestrant Alone in ER+ Breast Cancer Patients
Status: COMPLETED
Conditions: FGFR Inhibition, Pharmacokinetics, Biomarkers|ER+ Breast Cancer
Interventions: DRUG: AZD4547|DRUG: Exemestane|DRUG: Placebo|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study of Topical Cannabinoids for Treatment of Aromatase Inhibitor-Associated Musculoskeletal Syndrome (AIMSS) in Adults With Hormone Receptor-Positive Breast Cancer (CanAroma)
Status: ACTIVE_NOT_RECRUITING
Conditions: Musculoskeletal Syndrome
Interventions: DRUG: CBD-dominant|DRUG: THC dominant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treating Severe Chronic Epstein-Barr Virus (EBV) Infection With EBV Specific Cytotoxic T Lymphocytes (CTLs)
Status: COMPLETED
Conditions: Epstein-Barr Virus Infections
Interventions: BIOLOGICAL: Intravenous injection of EBV specific CTLS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Rising Doses of BI 163538 XX
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo to BI 163538 XX|DRUG: BI 163538 XX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Anti-reflux Mucosectomy (ARMS) is a Useful Therapy for Refractory Gastroesophageal Reflux Disease (RGERD)
Status: UNKNOWN
Conditions: Refractory Gastroesophageal Reflux Disease
Interventions: PROCEDURE: anti-reflux mucosectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimisation Strategy for Emergency Tracheal Intubation
Status: RECRUITING
Conditions: Emergencies|Out-of-hospital Setting|Tracheal Intubation
Interventions: OTHER: Data patient|OTHER: Physical examination|PROCEDURE: Rapid sequence intubation (RSI) : Rocuronium /Bag-mask ventilation /GEB|PROCEDURE: Rapid sequence intubation (RSI) : Recommendations for emergency intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost 0.005% to Preservative Free Tafluprost Eye Drops
Status: COMPLETED
Conditions: Ocular Hypertension|Open-Angle Glaucoma
Interventions: DRUG: tafluprost
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Look at Tapentadol Oral Solution in Children and Adolescents in Pain
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Tapentadol oral solution 4 mg/mL|DRUG: Tapentadol oral solution 20 mg/mL|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: His Bundle Pacing in Bradycardia and Heart Failure
Status: RECRUITING
Conditions: Bradycardia|Heart Failure
Interventions: PROCEDURE: CRT-D Implantation|PROCEDURE: CRT-P Implantation|PROCEDURE: Dual Chamber Pacemaker Implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Tregalizumab on Allergen-induced Airway Responses and Airway Inflammation in Asthmatic Patients
Status: COMPLETED
Conditions: Allergy to House Dust Mite|Allergic Asthma
Interventions: DRUG: Tregalizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tabalumab (LY2127399) Using Two Different Injection Methods in Participants With Lupus
Status: TERMINATED
Conditions: Lupus Erythematosus, Systemic
Interventions: DRUG: Tabalumab Auto-Injector|DRUG: Tabalumab Prefilled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Adding Either an HIV Vaccine, Interleukin-2, or Both to a Patient's Anti-HIV Drug Combination
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: ALVAC(2)120(B,MN)GNP (vCP1452)|DRUG: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Modulated Auditory Stimulation on Interaural Auditory Perception
Status: COMPLETED
Conditions: Asymmetric Sensorineural Hearing Loss
Interventions: OTHER: Auditory intervention filter-modulated group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Outpatient Treatment of Uncomplicated Diverticulitis With Either Antibiotic or Nonantibiotic Treatment
Status: COMPLETED
Conditions: Uncomplicated Diverticular Disease
Interventions: OTHER: Nonantibiotic treatment of uncomplicated diverticulitis|OTHER: Antibiotic treatment of uncomplicated diverticulitis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Three Combined Probiotics Supplementation on Weight Loss in Obese/Overweight Children
Status: COMPLETED
Conditions: Obesity, Childhood
Interventions: OTHER: L. rhamnosus bv-77, B. animalis subsp. lactis CP-9 and L. salivarius AP-32 mix probiotics powder|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Promoting Widowed Elders Lifestyle After Loss
Status: COMPLETED
Conditions: Mood Disorders|Depression|Anxiety|Grief|Bereavement|Health Behavior
Interventions: BEHAVIORAL: Behavioral self-monitoring|BEHAVIORAL: Behavioral self-monitoring + Motivational interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Metformin Plus Tyrosine Kinase Inhibitors for Treatment of Patients With Non-small Cell Lung Cancer With EGFR Mutations
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Metformin Hydrochloride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: True Ileal Amino Acid Digestibility of Tenebrio Molitor Larvae in Women
Status: COMPLETED
Conditions: Malnutrition; Protein
Interventions: OTHER: 2H intrinsically-labeled T.molitor with 13-C labeled amino acid mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Effectiveness of Endoscopic Intestinal Re-Cellularization Therapy in Individuals With Type II Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus|Type2diabetes|Diabetes Mellitus, Type 2|Diabetes|Type 2 Diabetes
Interventions: DEVICE: ReCET Treatment|DEVICE: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Peginterferon Alfa-2b Combined With TDF in Patients With Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Peginterferon alfa-2b injection|DRUG: Peginterferon alfa-2b injection|DRUG: TDF|DRUG: Peginterferon alfa-2b injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety and Efficacy of MN-221 as an Adjunct to Standard Therapy in Subjects Experiencing an Acute Exacerbation of Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: MN-221|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Multimodal Approach for the Treatment of Primary Progressive Aphasia
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Progressive Aphasia
Interventions: DEVICE: Active tDCS|DEVICE: Placebo tDCS|BEHAVIORAL: Language training|BEHAVIORAL: Unstructured cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sleeve Versus Bypass in Older Patients: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Obesity, Morbid|Surgery|Elderly
Interventions: PROCEDURE: Sleeve Gastrectomy|PROCEDURE: Gastric Bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Feeding Position on Pulmonary Morbidity in Young Children
Status: UNKNOWN
Conditions: Pulmonary Diseases|Tonsillar Hypertrophy|Otitis Media|Dental Caries
Interventions: BEHAVIORAL: upright feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose:
Clinical trial: Zimmer Biomet Shoulder Arthroplasty PMCF
Status: RECRUITING
Conditions: Shoulder Fractures|Shoulder Arthritis|Shoulder Osteoarthritis|Shoulder Deformity|Shoulder Injuries|Shoulder Pain
Interventions: DEVICE: Alliance Glenoid|DEVICE: Identity Stem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Gastric Motility and Distention in Postoperative Gastrointestinal Surgery Using Bedside Gastric Ultrasound: Predicting Risk of Aspiration Pneumonia, Ileus, Return of Bowel Function
Status: COMPLETED
Conditions: Postoperative Ileus|Postoperative Nausea|Postoperative Complications|Postoperative Nausea and Vomiting|Postoperative Vomiting|Aspiration Vomitus
Interventions: DIAGNOSTIC_TEST: Bedside gastric ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunogenicity and Safety Study of GSK's MenABCWY Vaccine in Healthy Adolescents and Adults Previously Primed With MenACWY Vaccine
Status: COMPLETED
Conditions: Meningitis, Meningococcal
Interventions: COMBINATION_PRODUCT: MenABCWY vaccine|COMBINATION_PRODUCT: Placebo|BIOLOGICAL: MenACWY vaccine|COMBINATION_PRODUCT: MenB vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation
Status: RECRUITING
Conditions: Paroxysmal Atrial Fibrillation
Interventions: BEHAVIORAL: Self- Report Evaluation-Duke Activity Status Index|BEHAVIORAL: Self- Report Evaluation Atrial Fibrillation Effect on Quality of Life Questionnaire|DIAGNOSTIC_TEST: Cardiopulmonary exercise test (CPET)|DIAGNOSTIC_TEST: Transthoracic echocardiogram|DIAGNOSTIC_TEST: Ambulatory cardiac rhythm assessment|DIAGNOSTIC_TEST: Cardiovascular magnetic resonance (CMR)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Controlled Pilot Trial of Indomethacin in Acute Pancreatitis
Status: COMPLETED
Conditions: Acute Pancreatitis
Interventions: DRUG: Indomethacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Eight Week, Double-Blind Efficacy Study of Armodafinil Augmentation to Alleviate Fibromyalgia Fatigue
Status: COMPLETED
Conditions: Fibromyalgia, Primary
Interventions: DRUG: armodafinil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stimulation of Cingulo-opercular Alertness Network
Status: RECRUITING
Conditions: Lewy Body Disease|Lewy Body Variant of Alzheimer Disease|Lewy Body Dementia With Behavioral Disturbance
Interventions: DEVICE: HD-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biological Clock Dysfunction in Optic Nerve Hypoplasia
Status: COMPLETED
Conditions: Biological Clock Dysfunction|Optic Nerve Hypoplasia
Interventions: DIETARY_SUPPLEMENT: Melatonin|DIETARY_SUPPLEMENT: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Long-acting Injectable Risperidone in the Treatment of Patients With Schizophrenia or Schizoaffective Disorder
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Changes and Glycemic Control in T1D
Status: UNKNOWN
Conditions: Type1 Diabetes Mellitus|Life Style|Behavioral Changes|Self-Management
Interventions: DEVICE: e-device for step count (fit-bit)|BEHAVIORAL: e-messages for log book|BEHAVIORAL: e-messages for log book & fit-bit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of the Effects of Physical Therapy With and Without Magnetic Field Therapy in People With Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: OTHER: Group 1 (Physical Therapy+Magnetic Field Therapy)|OTHER: Group 2 (Physical Therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Smartphone Training for Attention Regulation for IBS
Status: RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: BEHAVIORAL: Mindfulness and Attention Training|BEHAVIORAL: Mindfulness training|BEHAVIORAL: Coping Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Non-Small Cell Lung Cancer (NSCLC) Patients Receiving Second-Line Nivolumab Monotherapy in Asia
Status: COMPLETED
Conditions: Lung Cancer|Non-Small Cell Lung Cancer
Interventions: BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study to Provide Adjuvant Treatment Following Neoadjuvant Treatment and Surgical Resection in Protocol TX05-03
Status: COMPLETED
Conditions: HER2-positive Breast Cancer|Early-stage Breast Cancer|Breast Cancer|Breast Neoplasms|Stage II Breast Cancer|Stage IIIA Breast Cancer
Interventions: BIOLOGICAL: TX05 (trastuzumab)|BIOLOGICAL: Herceptin (trastuzumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety and Efficacy of Onartuzumab And/or Bevacizumab in Combination With Paclitaxel in Participants With Metastatic, Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Onartuzumab|DRUG: Bevacizumab|DRUG: Paclitaxel|DRUG: Bevacizumab Placebo|DRUG: Onartuzumab Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Auditory Brainstem Implant (ABI) in Pediatric Non-Neurofibromatosis Type 2 Subjects
Status: TERMINATED
Conditions: Bilateral Hearing Loss for Causes Other Than Tumors
Interventions: DEVICE: Nucleus 24 (discontinued) and ABI541 Auditory Brainstem Implants (ABI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Roxadustat for Treatment of Anemia in Participants With Lower Risk Myelodysplastic Syndrome With Low Red Blood Cell Transfusion Burden
Status: TERMINATED
Conditions: Primary MDS (Very Low, Low or Intermediate IPSS-R With <5% Blasts)|Anemia
Interventions: DRUG: Roxadustat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Celecoxib in Treating Women With Metastatic or Recurrent Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: celecoxib|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Elaprase in Children and Adults With Hunter Syndrome (Mucopolysaccharidosis II) in India
Status: ACTIVE_NOT_RECRUITING
Conditions: Hunter Syndrome
Interventions: BIOLOGICAL: Elaprase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fabry Disease in High-risk Patients With Left Ventricular Hypertrophy: Prevalence and Implementation of a Clinical Score
Status: ACTIVE_NOT_RECRUITING
Conditions: Fabry Disease|Fabry Disease, Cardiac Variant|Lysosomal Storage Diseases|HCM - Hypertrophic Cardiomyopathy|Anderson Fabry Disease
Interventions: DIAGNOSTIC_TEST: blood sampling (alpha-Galactosidase & LysoGb3)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: HOPE-B: Trial of AMT-061 in Severe or Moderately Severe Hemophilia B Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemophilia B
Interventions: GENETIC: AAV5-hFIXco-Padua|BIOLOGICAL: Factor IX (FIX)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Administration of Probiotics in Cirrhotic Patients Listed for Liver Transplantation
Status: COMPLETED
Conditions: Liver Cirrhosis
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Blue and Amber Light Exposure in Patients With Rectal and Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Neoplasms|Rectal Neoplasms
Interventions: DEVICE: Blue light|DEVICE: Amber light|OTHER: Ambient White Light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DNA Methylation for Screening Uterine Cervical Lesions: A Case-control Study
Status: UNKNOWN
Conditions: DNA Methylation|Uterine Cervical Cancer|High Grade Squamous Intraepithelial Lesions|Low Grade Squamous Intraepithelial Lesions
Interventions: DIAGNOSTIC_TEST: DNA methylation|DIAGNOSTIC_TEST: high-risk HPV|DIAGNOSTIC_TEST: TCT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial to Evaluate DR-2021 in Women With Secondary Amenorrhea
Status: COMPLETED
Conditions: Amenorrhea
Interventions: DRUG: DR-2021a|DRUG: DR-2021b|DRUG: DR-2021c|DRUG: DR-2021d|DRUG: DR-2021e|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of WB-EMS and Specific Dietary Supplements on Cancer Patients
Status: UNKNOWN
Conditions: Cancer|Cancer Cachexia|Weight Loss|Muscle Loss|Muscle Weakness
Interventions: DIETARY_SUPPLEMENT: β-hydroxy-β-methylbutyrate (HMB)|DIETARY_SUPPLEMENT: L-carnitine (LC)|DIETARY_SUPPLEMENT: Eicosapentaenoic acid (EPA)|OTHER: Whole-Body Electromyostimulation (WB-EMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: PFNA vs Dual Mobility in Treatment of Unstable Trochanteric Fractures
Status: NOT_YET_RECRUITING
Conditions: Trochanteric Fractures
Interventions: DEVICE: Proximal Femoral Nail|COMBINATION_PRODUCT: Dual Mobility Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Controlled Human Malaria Infections to Evaluate Protection After Intravenous or Intramuscular Administration of PfSPZ Vaccine in Malaria-Naive Adults
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: PfSPZ Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase I Trial of High-Dose Ascorbate in Glioblastoma Multiforme
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma|GBM|Glioblastoma Multiforme
Interventions: DRUG: Ascorbate|DRUG: Temozolomide|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Biomarker With 18F-FDG PET for Treatment Optimization of Anti-EGFR Therapy in Patients With Metastatic Colorectal Cancer.
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: (Early) Imaging of response with [18F-]-FDG PET-CT and kinase activity profiles
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Viral Therapy In Treating Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Cancer or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Estrogen Receptor Negative|Estrogen Receptor Positive|Head and Neck Squamous Cell Carcinoma|HER2/Neu Negative|HER2/Neu Positive|Invasive Breast Carcinoma|Progesterone Receptor Negative|Progesterone Receptor Positive|Recurrent Head and Neck Carcinoma|Stage IV Breast Cancer|Triple-Negative Breast Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Oncolytic Measles Virus Encoding Thyroidal Sodium Iodide Symporter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Benefits of Therapy With Nifurtimox in Chagas Disease, a Parasitic Illness Mostly Transmitted to Humans by a Bug, Using Information From Patient Medical Records in Argentina
Status: COMPLETED
Conditions: Chagas' Disease
Interventions: DRUG: Lampit (Nifurtimox, BAYA2502)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study To Compare The Amount Of CP-690,550 That Is Absorbed Into The Blood Of Healthy Subjects Following Oral Administration Of Two Different Strength Tablets Of CP-690,550
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Treatment A|DRUG: Treatment B|DRUG: Treatment B|DRUG: Treatment A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Photobiomodulation (PBM) Therapy on Muscle Performance in Elderly Women
Status: COMPLETED
Conditions: Lasers|Resistance Training|Muscle Strength|Aged|Performance
Interventions: RADIATION: Active laser|RADIATION: Placebo laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Suberoylanilide Hydroxamic Acid (SAHA), Bevacizumab, Daily Temozolomide for Recurrent Malignant Gliomas
Status: COMPLETED
Conditions: Brain Tumor|Glioblastoma
Interventions: DRUG: Vorinostst/Bevacizumab/Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of "UroShield" Device Impact Upon Side Effects and Complications of Urinary Catheter Usage
Status: WITHDRAWN
Conditions: Infectious
Interventions: DEVICE: UroShield device|DEVICE: Sham UroShield device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Determine the Degree of Additional Reduction in CV Risk in Lowering LDL Below Minimum Target Levels
Status: COMPLETED
Conditions: Cardiovascular Disease|Cerebrovascular Accident|Coronary Heart Disease
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Retention of Sealants Placement Using Two Isolation Systems
Status: COMPLETED
Conditions: Retention|Time|Patient Preference
Interventions: DEVICE: Dryshield|DEVICE: Cotton roll isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sevoflurane's Effect on Mitral Valve Annular Velocity in Cardiac Surgery
Status: COMPLETED
Conditions: Valvular Heart Disease
Interventions: DRUG: Sevoflurane dosage titration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Growth Hormone Administration on Cardiovascular Risk in Cured Acromegalics With Growth Hormone Deficiency
Status: COMPLETED
Conditions: Acromegaly|Growth Hormone Deficiency|Pituitary Disease
Interventions: DRUG: Recombinant human growth hormone|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Manual Therapy on Laryngeal Function Following Total Thyroidectomy
Status: RECRUITING
Conditions: Total Thyroidectomy
Interventions: BEHAVIORAL: Anterior Neck Manual Therapy|BEHAVIORAL: Pain Neuroscience Education|BEHAVIORAL: Neck Stretches|BEHAVIORAL: Scar massage|BEHAVIORAL: Voice Exercises|BEHAVIORAL: Placebo Anterior Neck Manual Therapy|BEHAVIORAL: Placebo Pain Neuroscience Education|BEHAVIORAL: Placebo Neck Stretches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Immunogenicity Study of Trivalent P2-VP8 Subunit Rotavirus Vaccine in Adults, Toddlers and Infants
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Trivalent P2-VP8 Subunit Rotavirus Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clarithromycin Versus Azithromycin in Treatment of Mild COVID-19 Infection
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Clarithromycin 500mg|DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of ABBV-3373 in Participants With Moderate to Severe Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis (RA)
Interventions: DRUG: ABBV-3373|DRUG: Placebo for ABBV-3373|DRUG: Adalimumab|DRUG: Placebo for adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Nab-Paclitaxel and Ramucirumab as Second-line Treatment for Patients With Metastatic Gastroesophageal Cancer
Status: COMPLETED
Conditions: Gastroesophageal Cancer
Interventions: DRUG: nab-paclitaxel|BIOLOGICAL: ramucirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Concomitant and Non-Concomitant Administration of RotaTeq® (V260) and Inactivated Poliomyelitis Vaccine in Healthy Chinese Infants (V260-074)
Status: COMPLETED
Conditions: Prevention of Rotavirus Gastroenteritis in Infants and Children Caused by Serotypes G1, G2, G3, G4, and G9
Interventions: BIOLOGICAL: RotaTeq (V260)|BIOLOGICAL: IPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of MSB-CAR001 in Subjects 6 Weeks Post an Anterior Cruciate Ligament Reconstruction
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Injury|Osteoarthritis
Interventions: BIOLOGICAL: MSB-CAR001 Combined With Hyaluronan|DRUG: Hyaluronan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Danoprevir/r in Healthy Volunteers China
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Danoprevir|DRUG: Ritonavir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Calcium Gluconate With Diosmin, Cabergoline and Cabergoline With Diosmin
Status: COMPLETED
Conditions: Ovarian Hyperstimulation Syndrome
Interventions: DRUG: Calcium Gluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of UB-221 as an Add-on Therapy in CSU Patients
Status: COMPLETED
Conditions: Urticaria Chronic
Interventions: BIOLOGICAL: UB-221
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AVE0005 (VEGF Trap) in Patients With Recurrent Symptomatic Malignant Ascites
Status: COMPLETED
Conditions: Ovarian Neoplasms
Interventions: DRUG: Aflibercept (ziv-aflibercept, AVE0005, VEGF trap, ZALTRAP®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab to the Preparative Regimen of Etoposide and Total Body Irradiation in Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Etoposide|RADIATION: Total Body Irradiation|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Ankle Block in Ankle Fractures
Status: UNKNOWN
Conditions: Ankle Fractures|Anesthesia, Local
Interventions: DRUG: 40ml of Ropivacaine 0.5% Injectable Solution|DRUG: 40ml of Ringer's Lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Optical Coherence Tomography (OCT) Intravascular Ultrasound (IVUS) Dual Imaging
Status: TERMINATED
Conditions: Coronary Artery Disease (CAD)
Interventions: PROCEDURE: Optical Coherence Tomography (OCT)|PROCEDURE: Intravascular Ultrasound (IVUS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intracystic Injection of NanoPac® in Subjects With Mucinous Cystic Pancreatic Neoplasms
Status: COMPLETED
Conditions: Pancreatic Mucinous-Cystic Neoplasm
Interventions: DRUG: NanoPac®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-dose Study to Assess Pharmacokinetics of Solifenacin Succinate Suspension in Children and Adolescents
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: Solifenacin succinate suspension 2.5 mg|DRUG: Solifenacin succinate suspension 5 mg|DRUG: Solifenacin succinate suspension 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simple and Evidence-based Examination and Treatment of Shoulder Pain in General Practice
Status: RECRUITING
Conditions: Shoulder Pain|Frozen Shoulder|Rotator Cuff Tendinosis|Myalgia|Rotator Cuff Impingement Syndrome|Rotator Cuff Tear or Rupture, Not Specified as Traumatic
Interventions: OTHER: Evidence based treatment strategy|OTHER: Targeted patient information package|OTHER: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Airway Integrated Nasal Packing With Different Material
Status: COMPLETED
Conditions: Postoperative Respiratory Complications|Pain, Postoperative.
Interventions: PROCEDURE: Nasopore|PROCEDURE: airway integrated Nasopore|PROCEDURE: airway-integrated Vaseline gauze
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Left Atrial Appendage Excision on Procedure Outcome in Patients With Persistent and Long-standing Persistent Atrial Fibrillation Undergoing Surgical Ablation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DEVICE: Surgical ablation of the left atrium (PVI+Box lesions)|DEVICE: Surgical ablation of the left atrium (PVI+Box lesions) and left atrial appendage cutting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin as Adjunctive to Insulin Therapy Over 26 Weeks in Patients With T1DM (EASE-3)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Empagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Diagnostic Performance of an Algorithm and a High Definition Classical Iterative Algorithm Positron Emission Tomography (PET) to 18Fluoro-deoxy-glucose (18FDG) in the Evaluation of Axillary Lymph Node Invasion of Breast Tumors
Status: TERMINATED
Conditions: Breast Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Preoperative Oral Carbohydrate Administration in Thoracic Surgery Patients
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer|Fasting|Postoperative Pneumonia
Interventions: DIETARY_SUPPLEMENT: Oral carbohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: TEA, ESB and Paravertebral Block During Single-lung Ventilation for Lung Resection
Status: RECRUITING
Conditions: Lung Diseases|Pain, Acute
Interventions: PROCEDURE: erector spinae block|PROCEDURE: paravertebral block anesthesia|PROCEDURE: Thoracic epidural anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ranolazine for the Prevention of Atrial Fibrillation After Electrical Cardioversion
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: DRUG: Ranolazine|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Clinical Validation of Next Generation Sequencing (NGS) and Patient-Derived Tumor Organoids (PDO) Guided Therapy in Patients With Advanced/ Inoperable Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma|Colorectal Cancer
Interventions: OTHER: Patient-Derived Tumor Organoids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dasatinib in Combination With Revlimid (and Dexamethasone)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Dasatinib, 70 mg + Lenalidomide, 15 mg + Dexamethasone, 40 mg|DRUG: Dasatinib, 70 mg + Lenalidomide, 20 mg + Dexamethasone, 40 mg|DRUG: Dasatinib, 100 mg + Lenalidomide, 20 mg + Dexamethasone, 40 mg|DRUG: Dasatinib, 100 mg + Lenalidomide, 25 mg + Dexamethasone, 40 mg|DRUG: Dasatinib, 140 mg + Lenalidomide, 25 mg + Dexamethasone, 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Treatment Stratification Based on PET Scan Response to Chemotherapy in Patients With Diffuse Large B-cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B-cell Lymphoma|Follicular Grade 3B Lymphoma
Interventions: DRUG: R-MEGACHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac CAtheterization for Bypass Graft Patency Rate Optimization: the CABG-PRO Randomized-controlled Pilot Study
Status: UNKNOWN
Conditions: Coronary Artery Bypass Graft Surgery
Interventions: PROCEDURE: bypass graft angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Preliminary Efficacy of FAB117-HC in Patients With Acute Traumatic Spinal Cord Injury
Status: UNKNOWN
Conditions: Acute Traumatic Spinal Cord Injury
Interventions: DRUG: FAB117-HC|OTHER: Control group|DRUG: FAB117-HC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Effectiveness of ALBENDAZOLIVERMECTIN Coformulation vs ALBENDAZOLE for Treatment of Intestinal Worms
Status: TERMINATED
Conditions: Helminthes; Infestation, Intestinal
Interventions: COMBINATION_PRODUCT: Albendazole and Ivermectin fixed dose coformulation|DRUG: Albendazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Multiple Dosing Regimens of IV Conivaptan in Subjects With Euvolemic or Hypervolemic Hyponatremia
Status: COMPLETED
Conditions: Hyponatremia|Euvolemia|Hypervolemia
Interventions: DRUG: Conivaptan|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mitomycin C and Ifosfamide in Treating Patients With Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: ifosfamide|DRUG: mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Choroidal Thickness During Changes in Intraocular Pressure and Arterial Blood Pressure
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Phenylephrine|DRUG: Sodium-Nitroprusside|DEVICE: Suction Cup|DEVICE: Goldmann applanation tonometer|DEVICE: 1060nm Optical coherence tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Study of Maxillary and Mandibular Splints Used for the Treatment of Masticatory Muscle Parafunction (FEA)
Status: UNKNOWN
Conditions: Jaw, Edentulous|Mouth, Edentulous
Interventions: DEVICE: Occlusal splint
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Brisk Walking in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Brisk walking and balance training|BEHAVIORAL: Upper limb exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Eight-Week Study Evaluating the Efficacy of Two Fixed Doses (250 mg Twice Daily and 100 mg Twice Daily) of SSR149415 in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: DRUG: SSR149415
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperthermia Treatment in Conjunction With Mitomycin C Versus Bacillus Calmette-Guérin Immunotherapy (BCG) for Superficial Bladder Cancer
Status: TERMINATED
Conditions: Urinary Bladder Diseases|Urinary Bladder Neoplasms|Urinary Bladder Cancer|Malignant Tumor of Urinary Bladder|Urologic Diseases|Urologic Neoplasms|Neoplasms|Neoplasms by Site
Interventions: DEVICE: Synergo + MMC|DRUG: Bacillus Calmette-Guérin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Adherence and Safety of Orthopedic Treatment of Idiopathic Scoliosis in Adolescents Using Information and Communication Technologies
Status: UNKNOWN
Conditions: Scoliosis Idiopathic|Scoliosis; Adolescence|Brace
Interventions: DEVICE: Treatment as usual + APP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: The Effect of Information and Coping With Anxiety Training Given to Women Before Hysterectomy on Their Level of Anxiety
Status: COMPLETED
Conditions: Hysterectomy|Anxiety
Interventions: OTHER: Information and Coping with Anxiety Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant Anti-PD-1 Antibody SHR-1210 and Radiation in Resectable Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Esophageal Neoplasms|Esophageal Diseases
Interventions: RADIATION: 3-DCRT or IMRT radiation|DRUG: anti-PD-1 antibody SHR-1210
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microneedle Versus Fractional CO₂ Laser for Skin Aging Treatment With Stem Cell Secretome in Indonesian Adult Women
Status: COMPLETED
Conditions: Skin Aging|Transepidermal Water Loss
Interventions: DEVICE: Fractional CO₂ Laser|DEVICE: Microneedle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT