pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Fluzone® Quadrivalent, Fluzone® Intradermal Quadrivalent, and Fluzone® High-Dose, Influenza Vaccines in Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluzone Quadrivalent vaccine, 2015-2016 formulation, No Preservative|BIOLOGICAL: Fluzone Intradermal Quadrivalent vaccine, 2015-2016 formulation|BIOLOGICAL: Fluzone Quadrivalent vaccine, 2015-2016 formulation, No Preservative|BIOLOGICAL: Fluzone High-Dose vaccine, 2015-2016 formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intrapartum Hydration
Status: COMPLETED
Conditions: Labor Stage, First|Labor Stage, Second
Interventions: OTHER: 0.9% Saline with glucose 5%|OTHER: Ringer lactate|OTHER: Ringer lactate - Controls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Study of Hylan G-F 20 to Preserve Cartilage in Osteoarthritis of the Knee
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DRUG: intra-articular injection of Hylan G-F 20
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Effects of ELDOA Versus Post Facilitation Stretching Technique in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Elongation Longitudinaux Avec Decoaption Osteo Articulaire|OTHER: Post Facilitation Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Magnetic Spinal Cord Stimulation for Freezing of Gait in Parkinson's Disease
Status: UNKNOWN
Conditions: Gait Disorders, Neurologic
Interventions: DEVICE: Non-invasive magnetic stimulation of the spinal cord|OTHER: Coil will not be connected to the stimulation device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of NGR-hTNF in Combination With Cisplatin in Solid Tumor
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: NGR-hTNF|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Multimodal Perioperative Analgesia With Periarticular Drug Injection in Total Knee Arthroplasty(TKA)
Status: COMPLETED
Conditions: Osteoarthritis,Knee
Interventions: DRUG: Ropivacaine|DRUG: Toradol|DRUG: Clonidine|DRUG: Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Endogenous Lactate in Brain Preservation and Counterregulatory Defenses Against Hypoglycemia
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Hypoglycemia Unawareness
Interventions: BEHAVIORAL: High intensity exercise|BEHAVIORAL: Lay down comfortably
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Piloting a Reinforcement Learning Tool for Individually Tailoring Just-in-time Adaptive Interventions
Status: NOT_YET_RECRUITING
Conditions: Overweight and Obesity|Overweight|Obesity
Interventions: BEHAVIORAL: ADAPT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Post Market Clinical Follow up Study With the Cervical Disc Prothesis MOVE®-C
Status: RECRUITING
Conditions: Discopathy|Herniated Cervical Disc|Stenoses, Spinal|Radiculopathy
Interventions: DEVICE: MOVE®-C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrauterine Lidocaine for Laminaria
Status: COMPLETED
Conditions: Abortion, Induced|Pain Management
Interventions: DRUG: Lidocaine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral and Intravenous Diltiazem Protocol for Emergency Department Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DRUG: Oral|DRUG: Intravenous drug
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Flow Restriction in Improving Muscle Strength of Patients With Hemophilic Ankle Arthropathy
Status: RECRUITING
Conditions: Hemophilia
Interventions: OTHER: Blood flow restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pancreas Cancer Surveillance Using an Abbreviated MRI
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreas Cancer
Interventions: DIAGNOSTIC_TEST: Abbreviated PB MRI|GENETIC: Gene mutation test|DIAGNOSTIC_TEST: Conventional follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Optimizing the Prehospital Use of Stroke Systems of Care-Reacting to Changing Paradigms-Implementation (OPUS-i)
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: OTHER: OPUS-i algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bryostatin 1 and Interleukin-2 in Treating Patients With Refractory Solid Tumors or Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Small Intestine Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: aldesleukin|DRUG: bryostatin 1
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Utility of Shanfield Implantation Technique During Creation of Mitrofanoff Procedure in Pediatric Age Group
Status: RECRUITING
Conditions: Bladder Dysfunction
Interventions: PROCEDURE: Shanfield implantation technique in Mitroffanof procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tegoprazan-containing Sequential for H. Pylori
Status: RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Tegoprazan-containing sequential H. pylori eradication therapy|DRUG: Esomeprazole-containing sequential H. pylori eradication therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mental Fatigue on the Cerebral Oxygenation During Endurance Exercise
Status: UNKNOWN
Conditions: Mental Fatigue|Near Infrared Spectroscopy|NIRS|Condition|Cerebral Heamodynamics
Interventions: BEHAVIORAL: Time to Exhaustion cycling test|BEHAVIORAL: Go/NoGo task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Nopales (Opuntia Spp.) on Lipoprotein Profile and Oxidative Stress in Moderately Hypercholesterolemic Adults
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: BEHAVIORAL: Food supplementation: nopales|BEHAVIORAL: Food supplementation: cucumber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Rehabilitation in Patients With Progressive Supranuclear Palsy
Status: COMPLETED
Conditions: Progressive Supranuclear Palsy
Interventions: OTHER: MIRT|OTHER: MIRT+Lokomat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AZD0486 as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL
Status: NOT_YET_RECRUITING
Conditions: B-cell Non-Hodgkin Lymphoma|Follicular Lymphoma (FL)|Diffuse Large B-Cell Lymphoma (DLBCL)
Interventions: DRUG: AZD0486
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexamethasone on Postoperative Inflammatory Factors
Status: UNKNOWN
Conditions: Inflammation
Interventions: DRUG: Dexamethasone Injection|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: AcoArt Litos PCB Below-the-knee Global Trial
Status: NOT_YET_RECRUITING
Conditions: Chronic Limb-Threatening Ischemia
Interventions: DEVICE: PCB|DEVICE: PTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: QuitAdvisorMD: A Point-of-care Tool for Brief Smoking Cessation Interventions
Status: UNKNOWN
Conditions: Smoking|Tobacco Use Disorder
Interventions: OTHER: QuitAdvisorMD Software Algorithm|BEHAVIORAL: Standard Smoking Cessation Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: RBX7455 Before Surgery for the Treatment of Operable Breast Cancer
Status: TERMINATED
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Breast Adenocarcinoma|Invasive Breast Carcinoma|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Triple-Negative Breast Carcinoma
Interventions: DRUG: Microbiota-based Formulation RBX7455
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Stereotactic Ablative Body Radiotherapy (SABR) for Early-Stage Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Breast Cancer Female|Breast Adenocarcinoma
Interventions: OTHER: Standard of Care Schedule Variation: SABR|PROCEDURE: Breast-conserving Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Intravenous Trappsol Cyclo (HPBCD) in Niemann-Pick Type C Patients
Status: COMPLETED
Conditions: Niemann-Pick Disease, Type C1
Interventions: DRUG: Hydroxypropyl-beta-cyclodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-center, Prospective Study for Mechanism and Risk Factors of Tracheal Tube-related Tongue Injury
Status: RECRUITING
Conditions: Tracheal Tube-related Tongue Injury
Interventions: DEVICE: Tracheal tube-tongue pressure is measured using a computerized occlusal analysis system based on T-Scan® technique, suitable for multi-point real-time monitoring of intraoral pressure.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Effect Observation for Electrical Pudendal Nerve Stimulation in Treating Urethral Pain Syndrome
Status: COMPLETED
Conditions: Pelvic Pain Syndrome
Interventions: PROCEDURE: Electrical pudendal nerve stimulation|PROCEDURE: Intravesical instillation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial in Adult Subjects With Spinocerebellar Ataxia
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinocerebellar Ataxias|Spinocerebellar Ataxia Genotype Type 1|Spinocerebellar Ataxia Genotype Type 2|Spinocerebellar Ataxia Genotype Type 3|Spinocerebellar Ataxia Genotype Type 6|Spinocerebellar Ataxia Genotype Type 7|Spinocerebellar Ataxia Genotype Type 8|Spinocerebellar Ataxia Genotype Type 10
Interventions: DRUG: Troriluzole|DRUG: Placebo|DRUG: Troriluzole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Long-Term Safety Study of Certolizumab Pegol (CZP) for Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Certolizumab Pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SUpPress SSI - Single Use Negative Pressure Wound Therapy (NPWT) to Reduce Surgical Site Infections
Status: COMPLETED
Conditions: Surgical Site Infection|Obesity|Diabetes|Cesarean Section Complications
Interventions: DEVICE: Negative Pressure Wound Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigation of Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Efficacy of Oral Danirixin in Symptomatic COPD Subjects With Mild to Moderate Airflow Limitation at Risk for Exacerbations
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Danirixin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cervical Arthroplasty Cost Effectiveness Study (CACES)
Status: RECRUITING
Conditions: Radiculopathy, Cervical|Myelopathy Cervical|Myelopathy, Compressive|Radiculopathy, Cervical Region|Radiculopathy; in Spondylosis|Radiculopathy; in Intervertebral Disc Disorder|Myelopathy Neurological|Myelopathy Due to Spondylosis|Cervical Disc Disease|Cervical Disc Herniation|Cervical Disc Degeneration|Cervical Disc Disorder With Myelopathy|Cervical Disc Prolapse With Myelopathy|Cervical Spondylosis|Cervical Fusion|Cervical Disc Disorder With Radiculopathy|Cervical Disc Prolapse With Radiculopathy|Fusion of Spine|Disc Prolapse Cervical
Interventions: PROCEDURE: ACDF|PROCEDURE: ACDA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A 16 Week Comparative Study of Fenofibrate Versus Ezetimibe as Add-on Therapy to Atorvastatin
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: fenofibrate|DRUG: ezetimibe|DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Non Small Cell Lung Cancer Trial of Durvalumab and Tremelimumab in Advanced Epidermal Growth Factor Receptor (EGFR) Mutant Disease.
Status: ACTIVE_NOT_RECRUITING
Conditions: EGFR Mutant Advanced Non Small Cell Lung Cancer
Interventions: DRUG: Tremelimumab|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Orthosis Versus Cast Immobilization for Partially Unstable Weber B Ankle Fractures
Status: RECRUITING
Conditions: Ankle Fractures
Interventions: DEVICE: Functional orthosis|DEVICE: Cast immobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Worksite Program to Prevent Weight Gain Among Bus Drivers
Status: COMPLETED
Conditions: Obesity|Cardiovascular Diseases|Heart Diseases
Interventions: BEHAVIORAL: Healthful eating and food choices behavior change programs and changes in worksite food availability and prices|BEHAVIORAL: Physical Activity|BEHAVIORAL: Environment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Aging, Aged Garlic, Vascular Function and Muscle Oxygenation
Status: COMPLETED
Conditions: Aging|Hypertension|Dyslipidemias|Abdominal Obesity
Interventions: DIETARY_SUPPLEMENT: Aged Garlic Extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I, First-In Human Study to Evaluate Safety and Tolerability of EuRSV in Healthy Adults Aged Between 19 Years and 80 Years
Status: RECRUITING
Conditions: Respiratory Syncytial Virus Infections|Respiratory Syncytial Virus (RSV)
Interventions: BIOLOGICAL: EuRSV|OTHER: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: IVF Hyper-responders: Oocyte Vitrification Compared With Embryo Freezing
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: oocyte vitrification|PROCEDURE: embryo freezing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin and Brain Responses in Maternal Addiction
Status: TERMINATED
Conditions: Maternal Behavior|Maternal Addiction
Interventions: DRUG: Oxytocin|DRUG: Placebos|PROCEDURE: Functional MRI scanning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety Study of ADV-specific T-cells in Paediatric Patients Post Allo-HSCT
Status: COMPLETED
Conditions: ADV Infection Post Allo-HSCT
Interventions: BIOLOGICAL: Cytovir-ADV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenetic Study of CellCept (Mycophenolate Mofetil) in Kidney Transplant Patients.
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: mycophenolate mofetil [CellCept]|DRUG: mycophenolate mofetil [CellCept]|DRUG: Cyclosporine or tacrolimus|DRUG: Cyclosporine or tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab in Combination With Tremelimumab in Subjects With Advanced Rare Solid Tumors
Status: RECRUITING
Conditions: Cancer|Rare Disease
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SMART Use of Medication for the Treatment of Adolescent Severe Obesity
Status: ACTIVE_NOT_RECRUITING
Conditions: Adolescent Obesity
Interventions: BEHAVIORAL: Lifestyle Modification Therapy (LSMT)|DRUG: Phentermine Pill|DRUG: Topiramate Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Measurement of the Partial Pressure of Oxygen in Cutaneous Tumors Using Electron Paramagnetic Resonance (EPR) Oximetry
Status: RECRUITING
Conditions: Skin Lesion|Skin Cancer|Skin Melanoma|Tumor Skin
Interventions: OTHER: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prevention of the Progression of Coronary Calcification With Use of Spironolactone in Peritoneal Dialysis Patients
Status: COMPLETED
Conditions: Coronary Artery Calcification|Vascular Calcification
Interventions: DRUG: Spironolactone 25Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pharmacokinetic Study of the Relative Bioavailability of Paliperidone ER Formulations With Different Release Profiles and a Comparison to Paliperidone IR
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tibial Nerve Versus Sciatic Nerve Block
Status: COMPLETED
Conditions: Post Operative Analgesia
Interventions: PROCEDURE: Selective Tibial Nerve block|PROCEDURE: Sciatic Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Dexamethasone Prevention for Patients of Ovarian Hyperstimulation Syndrome
Status: UNKNOWN
Conditions: Ovarian Hyperstimulation Syndrome
Interventions: DRUG: bromocriptine|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real World Outcomes Study of Hepatic Encephalopathy Patients' Experience on Rifaximin (PROSPER)
Status: COMPLETED
Conditions: Hepatic Encephalopathy
Interventions: OTHER: Prospective Phase Rifaximin-α 550mg|OTHER: Prospective Phase No Rifaximin-α 550mg|OTHER: Retrospective Phase
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Efficacy and Safety of Trastuzumab in Combination With Capecitabine and Oxaliplatin as First-line Chemotherapy for Inoperable, Locally Advanced or Recurrent and/or Metastatic Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Trastuzumab+Capecitabine+Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single and Multi-Dose Study, Pharmacokinetics of Oxycodone and PF614 Co-Administered With Nafamostat (PF614-MPAR-102)
Status: NOT_YET_RECRUITING
Conditions: Pharmacokinetics
Interventions: DRUG: PF614 capsule|DRUG: Nafamostat Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Dose Safety, Tolerability, PK Study of AL001 in Alzheimer's Disease Patients & Healthy Adult Subjects
Status: COMPLETED
Conditions: Alzheimer's Disease|Healthy Non-elderly and Elderly Adults
Interventions: DRUG: AL 001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Op Rotator Cuff Pain Study With Subacromial Bupivacaine Infusion
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: DRUG: 0.5% bupivacaine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Food for Thought: Virtual Home-Based Family Interventions to Improve Nutrition Behaviors
Status: COMPLETED
Conditions: Behavior, Health|Obesity, Childhood
Interventions: BEHAVIORAL: Healthier Families, COVID Edition|BEHAVIORAL: Teaching Kitchen Outreach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of a CSE With ADIM in Chronic Non-specific Low Back Pain With Lumbar Instability Using Telerehabilitation.
Status: RECRUITING
Conditions: Chronic Low-back Pain|Lumbar Instability
Interventions: OTHER: 7-week Core stabilization exercise with abdominal drawing-in maneuver technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CPAP or BiPAP for Motion Mitigation During Radiotherapy
Status: RECRUITING
Conditions: Radiotherapy Side Effect|NSCLC|Esophageal Cancer|Malignant Lymphoma
Interventions: DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparing and Combining Bortezomib and Mycophenolate in SSc Pulmonary Fibrosis
Status: COMPLETED
Conditions: Lung Diseases, Interstitial|Systemic Sclerosis|Scleroderma
Interventions: DRUG: Bortezomib|DRUG: Placebo|DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PF-06438179 (Infliximab-Pfizer) and Infliximab in Combination With Methotrexate in Subjects With Active Rheumatoid Arthritis (REFLECTIONS B537-02).
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: PF-06438179|BIOLOGICAL: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Prophylactic Hemoclips in the Endoscopic Resection of Large Pedunculated Polyps
Status: TERMINATED
Conditions: Postpolypectomy Bleeding
Interventions: DEVICE: Hemoclip|DEVICE: Conventional Polipectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Anesthesia Techniques in Symptomatic Mandibular Molars With Irreversible Pulpitis
Status: COMPLETED
Conditions: Anesthesia, Dental
Interventions: DEVICE: Inferior Alveolar Nerve Block Group|DEVICE: Intraligamentary Injection Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Precision Study Measuring Potassium (K) in Capillary Specimens
Status: RECRUITING
Conditions: Precision of Potassium (K) Test in Capillary Whole Blood
Interventions: DIAGNOSTIC_TEST: Fingerstick blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Dietary Counseling During Pregnancy on Infant Birthweight in Mangochi , Malawi
Status: COMPLETED
Conditions: Maternal Exposure During Pregnancy
Interventions: BEHAVIORAL: Community based dietary counselling|BEHAVIORAL: Community based antenatal counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Renin-Angiotensin and Fibrinolysis in Humans: Effect of Long-Term PDE5 Inhibition on Glucose Homeostasis
Status: TERMINATED
Conditions: Impaired Glucose Tolerance
Interventions: DRUG: Sildenafil|DRUG: Placebo|DIAGNOSTIC_TEST: Hyperglycemic clamp|DIAGNOSTIC_TEST: Euglycemic clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of PF-05082566 In Combination With Mogamulizumab In Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced/Metastatic Solid Tumors
Interventions: DRUG: PF-05082566|DRUG: KW-0761
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Hypersensitivity Using Diode Laser and Desensitising Agent on Fluorosed and Non-fluorosed Teeth
Status: COMPLETED
Conditions: Fluorosis, Dental|Non-Fluoride Enamel Opacities|Dentin Sensitivity
Interventions: PROCEDURE: Fluorosed Group|PROCEDURE: Non Flourosed Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cytokine Adsorption in Severe, Refractory Septic Shock
Status: COMPLETED
Conditions: Septic Shock|Cytokine Storm
Interventions: DEVICE: Cytokine Adsorption|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multimodality Treatment Approach to Patients With Inflammatory Cancer of the Breast and Locally Advanced Non-Inflammatory Stage III Breast Cancer and Stage IV Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Neoplasm Metastasis
Interventions: PROCEDURE: high dose melphalan and autologous bone marrow transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Vitality in Infants Via Azithromycin for Neonates Trial
Status: NOT_YET_RECRUITING
Conditions: Neonatal Death|Infectious Disease|Nutritional Deficiency
Interventions: DRUG: Azithromycin at Baseline|DRUG: Azithromycin at Day 21|OTHER: Placebo at Baseline|OTHER: Placebo at Day 21
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Macrocomposition on Nonalcoholic Fatty Liver Disease (NAFLD) in Bariatric Surgery Candidates
Status: COMPLETED
Conditions: Morbid Obesity|Non-alcoholic Fatty Liver Disease
Interventions: OTHER: low carbohydrate diet|OTHER: low-fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Dupilumab in Patients With Nasal Polyposis And Chronic Symptoms Of Sinusitis
Status: COMPLETED
Conditions: Nasal Polyps
Interventions: DRUG: Placebo (for dupilumab)|DRUG: Dupilumab|DRUG: Mometasone furoate nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Pyridoxal 5' -Phosphate in the Treatment of Tardive Dyskinesia
Status: TERMINATED
Conditions: Tardive Dyskinesia
Interventions: DRUG: Pyridoxal 5'-Phosphate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Zinc and/or Probiotic Supplementation of Rotavirus and Oral Polio Virus Vaccines
Status: COMPLETED
Conditions: Immunity to Oral Rotavirus Vaccine|Immunity to Oral Polio Vaccine|Shedding of Oral Rotavirus Vaccine
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Zinc|DIETARY_SUPPLEMENT: Probiotic placebo|DIETARY_SUPPLEMENT: Zinc placebo|BIOLOGICAL: Rotavirus vaccine|BIOLOGICAL: Oral polio vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Temsirolimus in Treating Patients With Metastatic Solid Tumor or Lymphoma That Cannot Be Removed By Surgery Who Have Different Levels of Liver Function
Status: COMPLETED
Conditions: Hepatic Complications|Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: temsirolimus|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Immunogenicity Trial With an Adjuvanted Tuberculosis(TB) Subunit Vaccine
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: 50 microgram antigen (Ag85B + ESAT-6)|BIOLOGICAL: 50 microgram antigen (Ag85B + ESAT-6) + 100 nmol KLK + 4 nmol ODN1a|BIOLOGICAL: 50 microgram antigen (Ag85B + ESAT-6) + 500 nmol KLK + 20 nmol ODN1a
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Remineralizing Effect of Different Silver-containing Agents on Initial Caries Lesions in Primary Teeth in Children
Status: RECRUITING
Conditions: White Spot Lesion of Tooth
Interventions: DRUG: NSF|DRUG: SDF+KI|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risperidone or Cognitive-Behavioral Therapy for Improving Medication Treatment for Obsessive-compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: Risperidone|BEHAVIORAL: Exposure/ritual prevention therapy (EX/RP)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Palliative Treatment of Ulcerated Cutaneous Metastases: Trial Between Electrochemotherapy and Radiotherapy
Status: WITHDRAWN
Conditions: Ulcerated Cutaneous Metastases
Interventions: DRUG: Electrochemotherapy|RADIATION: Radiotherapy|DRUG: Bleomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cost-utility of Two Strategies of Perineal Reconstruction After Abdominoperineal Resection for Anorectal Carcinoma
Status: UNKNOWN
Conditions: Abdominoperineal Resection
Interventions: PROCEDURE: Biological mesh|PROCEDURE: Primary perineal wound closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PVSRIPO for Recurrent Glioblastoma (GBM)
Status: COMPLETED
Conditions: GBM|Glioblastoma|Glioma|Malignant Glioma
Interventions: BIOLOGICAL: Recombinant nonpathogenic polio-rhinovirus chimera (PVSRIPO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spacing of TNF-blocker Injections in Rheumatoid Arthritis Study
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: progressive spacing of TNF-blocker injections|DRUG: DMARD maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Combination Olanzapine+Lithium or Chlorpromazine+Lithium in Treatment of First Manic Episode With Psychotic Features
Status: COMPLETED
Conditions: Bipolar Disorder|Schizoaffective Disorder
Interventions: DRUG: Olanzapine|DRUG: Lithium|DRUG: Chlorpromazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Three Doses of Aclidinium Bromide Compared to Placebo and to an Active Comparator in Chronic Obstructive Pulmonary Disease (COPD) Patients.
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Aclidinium bromide 100 μg bid|DRUG: Aclidinium bromide 200 μg bid|DRUG: Aclidininum bromide 400 μg bid|DRUG: Placebo|DRUG: Formoterol 12 μg bid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Postoperative Cognitive-related Adverse Reactions and Brain Metabolomic Characteristics in Elderly Patients
Status: RECRUITING
Conditions: POCD - Postoperative Cognitive Dysfunction
Interventions: OTHER: Collecting clinical data, EGG，Brain Metabolomic Characteristics(with Magnetic Resonance Spectroscopy), blood gas data and blood sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of Whole Body Hyperthermia for Advanced Cancer
Status: RECRUITING
Conditions: Advanced Cancer|Pancreatic Cancer Metastatic
Interventions: DEVICE: Whole body hyperthermia|DRUG: Standard of Care (SOC) chemotherapy according to the NCCN guidelines.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Effect of Food on ABT-143 Bioavailability
Status: COMPLETED
Conditions: Pharmacokinetic Variables
Interventions: DRUG: ABT-143 ( rosuvastatin calcium and fenofibric acid )|DRUG: ABT-143 (rosuvastatin calcium and fenofibric acid )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: YKL-40 in Serum Samples From Patients With Newly Diagnosed Stage III-IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer Receiving Chemotherapy
Status: TERMINATED
Conditions: Fallopian Tube Adenocarcinoma|Fallopian Tube Clear Cell Adenocarcinoma|Fallopian Tube Endometrioid Adenocarcinoma|Fallopian Tube Mucinous Adenocarcinoma|Fallopian Tube Serous Adenocarcinoma|Fallopian Tube Transitional Cell Carcinoma|Malignant Ovarian Brenner Tumor|Malignant Ovarian Clear Cell Tumor|Malignant Ovarian Endometrioid Tumor|Malignant Ovarian Mixed Epithelial Tumor|Malignant Ovarian Mucinous Tumor|Malignant Ovarian Neoplasm|Malignant Ovarian Serous Tumor|Malignant Ovarian Transitional Cell Tumor|Ovarian Adenocarcinoma|Primary Peritoneal Serous Adenocarcinoma|Stage IIIA Fallopian Tube Cancer|Stage IIIA Ovarian Cancer|Stage IIIA Primary Peritoneal Cancer|Stage IIIB Fallopian Tube Cancer|Stage IIIB Ovarian Cancer|Stage IIIB Primary Peritoneal Cancer|Stage IIIC Fallopian Tube Cancer|Stage IIIC Ovarian Cancer|Stage IIIC Primary Peritoneal Cancer|Stage IV Fallopian Tube Cancer|Stage IV Ovarian Cancer|Stage IV Primary Peritoneal Cancer|Undifferentiated Fallopian Tube Carcinoma|Undifferentiated Ovarian Carcinoma
Interventions: OTHER: Cytology Specimen Collection Procedure|OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioavailability Study of Tranylcypromine 10mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: To Determine the Bioavailability of Tranylcypromine
Interventions: DRUG: Tranylcypromine|DRUG: Parnate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Safety and Pharmacokinetic Study of PF-06700841 in Japanese Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06700841|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Increasing the Accessibility of a Falls Prevention Intervention for Community Dwelling Older Adults With Low Vision
Status: COMPLETED
Conditions: Low Vision|Fall
Interventions: BEHAVIORAL: Original SAFE Intervention|BEHAVIORAL: Adapted SAFE Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Treatment BI 1744 CL (5 and 10 mcg) Versus Placebo on Exercise Endurance Time During Constant Work Rate Cycle Ergometry II
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Olodaterol (BI 1744)|DRUG: Olodaterol (BI 1744)|DRUG: Placebo|DRUG: Olodaterol (BI1744)|DRUG: Olodaterol (BI 1744) placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Acute Undifferentiated Leukemia|Childhood T Acute Lymphoblastic Leukemia
Interventions: DRUG: Asparaginase|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Biopsy|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Daunorubicin Hydrochloride|DRUG: Dexamethasone|PROCEDURE: Echocardiography|DRUG: Etoposide|BIOLOGICAL: Filgrastim|OTHER: Laboratory Biomarker Analysis|DRUG: Lestaurtinib|DRUG: Leucovorin Calcium|DRUG: Mercaptopurine|DRUG: Methotrexate|DRUG: Methylprednisolone|PROCEDURE: Multigated Acquisition Scan|DRUG: Pegaspargase|OTHER: Pharmacological Study|DRUG: Prednisone|DRUG: Therapeutic Hydrocortisone|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Study of Tesevatinib in Subjects With NSCLC and Brain or Leptomeningeal Metastases
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer|Leptomeningeal Metastases|Brain Metastases
Interventions: DRUG: Tesevatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of CK0801 (a New Drug) in Patients With Bone Marrow Failure Syndrome (BMF)
Status: ACTIVE_NOT_RECRUITING
Conditions: Bone Marrow Disease
Interventions: BIOLOGICAL: CK0801
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate EB-001 in Reducing Musculoskeletal Pain
Status: COMPLETED
Conditions: Musculoskeletal Pain
Interventions: DRUG: Placebo|DRUG: EB-001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omega-3 and Exercise in Rheumatoid Arthritis People
Status: ACTIVE_NOT_RECRUITING
Conditions: Arthritis, Rheumatoid
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Omega-3|DIETARY_SUPPLEMENT: Aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 2 Trial of Almonertinib With Concurrent Radiotherapy in The Treatment of Local Advanced EGFR-mutant NSCLC
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer|Stage III NSCLC|EGFR Activating Mutation
Interventions: DRUG: Almonertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Levodopa-Carbidopa on Visual Function in Patients With Recent-Onset Nonarteritic Anterior Ischemic Optic Neuropathy
Status: COMPLETED
Conditions: Nonarteritic Anterior Ischemic Optic Neuropathy
Interventions: DRUG: levodopa-carbidopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficiency of Ritalin in Multiple Sclerosis (MS) Patients
Status: UNKNOWN
Conditions: Relapsing Remitting Multiple Sclerosis|Multiple Sclerosis, Chronic Progressive
Interventions: DRUG: Ritalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: ECT
Clinical trial: A First in Human (FIH) Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DR10624
Status: RECRUITING
Conditions: Healthy, Obesity, Metabolically
Interventions: DRUG: DR10624 for injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ultrasound-guided Location of Laryngeal Mask With Air Leakage Test
Status: UNKNOWN
Conditions: Laryngeal Mask
Interventions: DEVICE: ultrasound|DIAGNOSTIC_TEST: air leakage test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Fasting Study of Paroxetine Hydrochloride Tablets 40 mg and Paxil® Tablets 40 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Paroxetine hydrochloride 40 mg tablet|DRUG: Paxil® 40 mg Table
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Prospective, Randomised Long-term Follow-up of Operative Versus Non-operative Treatment of Gr. 3 Acromioclavicular Dislocation
Status: COMPLETED
Conditions: Acromioclavicular Joint|Dislocation|Surgical Procedures, Operative
Interventions: PROCEDURE: Non-surgical group|PROCEDURE: Surgical group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induced Tolerogenic Dendritic Cells as Modulators of Allergic Asthma
Status: COMPLETED
Conditions: Asthma|Allergies
Interventions: BIOLOGICAL: Bronchoscopy, Segmental Allergen Challenge and Bronchoalveolar Lavage|PROCEDURE: Phlebotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Narrow Band Imaging in the Characterization of Residual Neoplasia After Endoscopic Piecemeal Mucosal Resection
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DEVICE: WLE|DEVICE: NBI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Lavare Cycle in Patients Receiving HeartWare Left Ventricular Assist Device
Status: TERMINATED
Conditions: Thromboembolism|Hemolysis|Stroke
Interventions: DEVICE: Lavare On|DEVICE: Lavare Off
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: KSD-101 Therapy for EBV-associated Nasopharyngeal Carcinoma: an Exploratory Clinical Trial
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: BIOLOGICAL: KSD-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Novel Nasoalveolar Molding Techniques on Parents' Satisfaction and Short Term Treatment Outcomes in Unilateral Cleft Lip and Palate Infants: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Cleft Lip and Palate
Interventions: DEVICE: Modified Nasoalveolar molding|DEVICE: Taping|DEVICE: CAD/NAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulsed Radiofrequency of Suprascapular Nerve and Shoulder Joint for Chronic Shoulder Pain
Status: UNKNOWN
Conditions: Chronic Shoulder Pain
Interventions: DRUG: licocain|OTHER: pulsed radiofrequency stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT