pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Lesion Progression of Approximal Caries After Resin Infiltration
Status: WITHDRAWN
Conditions: Proximal Caries
Interventions: DEVICE: Duraphat|DEVICE: Icon approximal caries infiltration kit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraosseous Local Anesthesia System in Children With Molar Incisor Hypomineralization
Status: NOT_YET_RECRUITING
Conditions: Molar Incisor Hypomineralization|Hypersensitivity|Composite Restoration
Interventions: DRUG: (%4 articaine with 1:200 000 adrenaline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Caregiver-involved Group-based NDBIs Intervention for Autistic Preschoolers
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Group-based Naturalistic Developmental Behavioral Intervention|BEHAVIORAL: One-on-one Naturalistic Developmental Behavioral Intervention|BEHAVIORAL: ASD Diagnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Intrathecal Hydromorphone for Pediatric Idiopathic Scoliosis Repair
Status: RECRUITING
Conditions: Pain Control
Interventions: DRUG: Hydromorphone 2.5 mcg/kg|DRUG: Hydromorphone 2.75 mcg/kg|DRUG: Hydromorphone 3 mcg/kg|DRUG: Hydromorphone 3.25 mcg/kg|DRUG: Hydromorphone 3.5 mcg/kg|DRUG: Hydromorphone 4 mcg/kg|DRUG: Hydromorphone 4.5 mcg/kg|DRUG: Hydromorphone 5 mcg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Socioemotional Intervention for Children With Autism Spectrum Disorder in Hong Kong and Mainland China
Status: UNKNOWN
Conditions: Autism Spectrum Disorder
Interventions: OTHER: Intervention on socioemotional functioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of AEYE-DS Software Device for Automated Detection of Diabetic Retinopathy From Digital Funduscopic Images
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetic Retinopathy
Interventions: DEVICE: AEYE-DS Software
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multicentre, Randomised Phase III Study of the Efficacy and Safety of Hetrombopag Olamine in Idiopathic Thrombocytopenic Purpura (ITP) Patient
Status: COMPLETED
Conditions: Idiopathic Thrombocytopenic Purpura
Interventions: DRUG: Hetrombopag Olamine|DRUG: matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigational Test of a New Sleep Supplement
Status: COMPLETED
Conditions: Sleep|Mood|Cognitive Performance
Interventions: DIETARY_SUPPLEMENT: Proprietary Spearmint Extract Blend|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Endoscopic Gastric Mucosal Devitalization (GMD) as a Primary Obesity Therapy - Part 2
Status: COMPLETED
Conditions: Obesity|Obesity, Morbid|Obesity; Endocrine|Bariatric Surgery Candidate
Interventions: PROCEDURE: Gastric mucosal devitalization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Palm Tocotrienols on Skin Biophysical Properties
Status: TERMINATED
Conditions: Wrinkle
Interventions: OTHER: Facial cream with 2% palm tocotrienols extract|OTHER: Base cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Drug Levels of MYK-224 Administered in Single and Multiple Doses in Healthy Adult Japanese Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: MYK-224|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Albuterol and Dynamic Hyperinflation in Idiopathic Pulmonary Arterial Hypertension
Status: WITHDRAWN
Conditions: Idiopathic Pulmonary Arterial Hypertension.
Interventions: DRUG: Albuterol.|DRUG: Normal saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Versus Standard Dose Dexamethasone for Reduction of Swelling in Patients With Primary or Metastatic Brain Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Brain Neoplasm|Metastatic Malignant Neoplasm in the Brain|Recurrent Malignant Brain Neoplasm
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Characterize the Safety, PK and Biological Activity of CC-930 in Idiopathic Pulmonary Fibrosis (IPF)
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis|Pulmonary Fibrosis|Fibrosis|Interstitial Lung Disease|Lung Diseases, Interstitial
Interventions: DRUG: CC-930|OTHER: Placebo|DRUG: CC-930|DRUG: CC-930
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gefitinib With or Without Tamoxifen in Treating Patients With Tamoxifen-Resistant Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: gefitinib|DRUG: tamoxifen citrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Personalised Pharmacological Approach to the Tapering of Corticosteroid Doses in Systemic Lupus Patients Treated With Prednisone
Status: COMPLETED
Conditions: Lupus Erythematosus, Systemic
Interventions: OTHER: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Obstructive Pulmonary Disease by Infusion of Allogenic Mesenchymal Stem Cells
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: UMC119-06-05
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Plitidepsin (Aplidin®) in Combination With Cytarabine in Patients With Relapsed/Refractory Leukemia
Status: TERMINATED
Conditions: Relapsed/Refractory Leukemia
Interventions: DRUG: Plitidepsin plus Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Non-Operating Room Anesthesia (NORA) Safety Video on Clinician Anxiety and Perceived Self-Efficacy
Status: COMPLETED
Conditions: Anxiety|Self Efficacy
Interventions: BEHAVIORAL: Video
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Impact Of Clinical Pharmacists Medication Reconciliation Upon Patients Admission To Reduce Medication Discrepancies.
Status: COMPLETED
Conditions: Medication Reconcilitation Upon Hospital Admission
Interventions: OTHER: medication reconciliation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: EINSTEIN Junior: Oral Rivaroxaban in Children With Venous Thrombosis
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation Therapy in Patients With Head and Neck Cancer Post-Radiotherapy
Status: COMPLETED
Conditions: Head and Neck Cancer|Head and Neck Neoplasms|Xerostomia
Interventions: DEVICE: Energy density photobiomodulation (7.5)|DEVICE: Sham placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Efficacy of Twice Daily Application of Topical BioLexa in Adult Healthy Subjects and Patients With Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: BioLexa- Cohort 1|DRUG: BioLexa- Cohort 2|DRUG: Placebo|DRUG: Gentamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Constraint Therapy and Bimanual Therapy for Children With Unilateral Brain Injury
Status: UNKNOWN
Conditions: Hemiplegia|Cerebral Palsy
Interventions: BEHAVIORAL: Bimanual hand therapy|BEHAVIORAL: Constraint therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Study of a New Taxane and Capecitabine in Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Cancer
Interventions: DRUG: larotaxel|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opiates Prescribing for Knee Arthroscopies and ACL Reconstruction
Status: COMPLETED
Conditions: Knee Injuries|ACL Injury
Interventions: OTHER: Group 1-Knee Arthroscopy|OTHER: Group 2-Knee Arthroscopy|OTHER: Group 1-ACL reconstruction|OTHER: Group 2-ACL reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Dentinal Hypersensitivity
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: DEVICE: Experimental Oral Rinse 1|DEVICE: Experimental Oral Rinse 2|OTHER: Placebo Oral Rinse|DRUG: Standard fluoride toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab Monotherapy for EBV-HLH and CAEBV
Status: UNKNOWN
Conditions: Secondary Hemophagocytic Lymphohistiocytosis|Chronic Active Epstein-Barr Virus Infection
Interventions: DRUG: Rituximab Monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Memantine on Radiotherapy-related Cognitive Impairment
Status: RECRUITING
Conditions: Cognitive Impairment
Interventions: DRUG: Memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: UCB Proof of Concept Study in Patients With Primary Sjögren's Syndrome
Status: TERMINATED
Conditions: Primary Sjögren's Syndrome
Interventions: DRUG: UCB5857|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Evaluate MR-guided Laser Ablation of Focal Lesions in Patients With Medically Refractory Partial Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: PROCEDURE: Laser ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spectroscopic MRI, Proton Therapy, and Avastin for Recurrent Glioblastoma
Status: RECRUITING
Conditions: Recurrent Glioblastoma
Interventions: RADIATION: Intensity Modulated Proton Therapy (IMPT)|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Altura Abdominal Aortic Aneurysm (AAA) Endograft Safety and Feasibility Study
Status: UNKNOWN
Conditions: Abdominal Aortic Aneurysms
Interventions: DEVICE: Altura Medical Abdominal Aortic Aneurysm Stent-Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preimplantation Genetic Diagnosis (PGD) by Array Comparative Genome Hybridization (CGH) and Blastocyst Biopsy
Status: TERMINATED
Conditions: Infertility|Miscarriage
Interventions: GENETIC: Preimplantation Genetic Diagnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAMPSIITE™ RGX-121 Gene Therapy in Subjects With MPS II (Hunter Syndrome)
Status: ACTIVE_NOT_RECRUITING
Conditions: Mucopolysaccharidosis Type II (MPS II)
Interventions: GENETIC: RGX-121
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Cardiac Effects of Padsevonil in Healthy Study Participants
Status: TERMINATED
Conditions: Healthy Study Participants
Interventions: DRUG: Padsevonil|DRUG: Moxifloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Leucine Supplementation in Young Subjects Undergoing Resistance Training
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Leucine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Effect of Trabeculectomy & Ex-PRESS Glaucoma Drainage Implant on the Corneal Biomechanical Properties
Status: COMPLETED
Conditions: Glaucoma Eye
Interventions: PROCEDURE: Ex-Press mini shunt insertion|PROCEDURE: Trabeculectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient-centered Self-administered Acupressure for Fatigue Management in Chinese Advanced Cancer Patients
Status: COMPLETED
Conditions: Advanced Cancer|Acupressure
Interventions: BEHAVIORAL: Self-administered acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fluorescent Cholangiography vs White Light for Bile Ducts Identification
Status: COMPLETED
Conditions: Cholecystitis|Cholelithiasis
Interventions: PROCEDURE: Laparoscopic cholecystectomy with Xenon light|PROCEDURE: Laparoscopic cholecystectomy (fluorescent cholangiography)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Establish Bioequivalence of ReFacto AF (BDDrFVIII) With Advate (FLrFVIII) in Hemophilia A
Status: COMPLETED
Conditions: Hemophilia A
Interventions: GENETIC: ReFacto AF|GENETIC: B-Domain deleted Recombinant Factor VIII|GENETIC: BDDrFVIII
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Evaluation and Validation of Metabolic Markers for the Assessment of CYP3A Activity and Prediction of DDI
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Midazolam|DRUG: itraconazole|DRUG: rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial Evaluating the Effectiveness of Contrave in Patients Who Have Weight Recidivism Following Bariatric Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: DRUG: Contrave 8Mg-90Mg Extended-Release Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First in Human Study to Assess Safety of VIS649 in Healthy Subjects
Status: COMPLETED
Conditions: Immunoglobulin A Nephropathy|IgAN - IgA Nephropathy|IgA Nephropathy
Interventions: BIOLOGICAL: VIS649|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Acetium Lozenges in Intervention for Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Acetium Lozenge|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Efficacy and Safety of Pulsed Radiofrequency Combined With Continuous Radiofrequency for the Trigeminal Neuralgia
Status: COMPLETED
Conditions: Trigeminal Neuralgia
Interventions: PROCEDURE: High-voltage pulsed radiofrequency|PROCEDURE: Low-temperature continuous radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STA-21 Topical Efficacy on Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Topical application of STA-21 ointment for treatment of psoriasis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of MPB-2043 Enhanced MRI for Nodal Staging in Head and Neck Squamous Cell Carcinomas
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma|Lymph Node Metastasis
Interventions: DRUG: MPB-2043 of 0.5 mg/kg|DRUG: MPB-2043 of 1.0 mg/kg|DRUG: MPB-2043 of 2.0 mg/kg|DRUG: MPB-2043 of 3.0 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: An Analysis of Dermabond vs. Non-Absorbable Sutures in Skin Closure for Brow Ptosis Procedures
Status: COMPLETED
Conditions: Brow Ptosis|Surgical Wound
Interventions: DEVICE: Dermabond|OTHER: Non-Absorbable Sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Respiratory and Autonomic Plasticity Following Intermittent Hypoxia
Status: COMPLETED
Conditions: Sleep Apnea Syndromes
Interventions: DRUG: Antioxidant cocktail
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Optimized PEEP on Mechanical Ventilation During Robot Assisted Laparoscopic Prostatectomy
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DEVICE: conventional PEEP|DEVICE: optimized PEEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of MK-8189 in Participants With an Acute Episode of Schizophrenia (MK-8189-008)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: MK-8189|DRUG: Risperidone|DRUG: Placebo to MK-8189|DRUG: Placebo to risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare Elbow mNT-BBAVF With Wrist RCAVF for Hemodialysis Access
Status: UNKNOWN
Conditions: End Stage Renal Disease on Dialysis
Interventions: PROCEDURE: mNT-BBAVF|PROCEDURE: RCAVF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Merck Carotid Atherosclerosis Trial (MK-0000-111)(COMPLETED)
Status: COMPLETED
Conditions: Carotid Atherosclerosis
Interventions: DRUG: Atorvastatin/niacin extended-release|DRUG: Atorvastatin|DRUG: Simvastatin|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Azithromycin for Uncomplicated Severe Acute Malnutrition in Burkina Faso (Pilot)
Status: COMPLETED
Conditions: Uncomplicated Severe Acute Malnutrition
Interventions: DRUG: Azithromycin|DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact Evaluation of Use of MATCH AI Predictive Modelling for Identification of Hotspots for TB Active Case Finding
Status: RECRUITING
Conditions: Tuberculosis
Interventions: OTHER: Camps site selection for active case finding for TB using MATCH-AI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: CaboCHECK - Cabozantinib in Adult Patients With Advanced Renal Cell Carcinoma Following Prior Systemic Check Point Inhibition Therapy: a Retrospective, Non-interventional Study
Status: TERMINATED
Conditions: Advanced Renal Cell Carcinoma (All Subtypes)|Metastatic Renal Cell Carcinoma (All Subtypes)
Interventions: OTHER: Documentation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sleep and Inflammatory Resolution Pathway
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammatory Response|Inflammation|Sleep|Sleep Restriction
Interventions: DRUG: Aspirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Visual Outcomes After Myopic LASIK
Status: COMPLETED
Conditions: Myopia|Astigmatism|Myopic Astigmatism
Interventions: PROCEDURE: Conventional LASIK|PROCEDURE: Wavefront-guided LASIK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Ewing's Sarcoma or Primitive Neuroectodermal Tumor
Status: COMPLETED
Conditions: Neutropenia|Sarcoma
Interventions: BIOLOGICAL: filgrastim|DRUG: amifostine trihydrate|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: ifosfamide|DRUG: topotecan hydrochloride|DRUG: vincristine sulfate|PROCEDURE: conventional surgery|RADIATION: low-LET cobalt-60 gamma ray therapy|RADIATION: low-LET electron therapy|RADIATION: low-LET photon therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NSPT on Calprotectin and Periostin Levels
Status: RECRUITING
Conditions: Chronic Periodontitis|Cardiovascular Diseases|Periodontal Inflammation
Interventions: PROCEDURE: Non Surgical Periodontal Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Ibuprofen Delay Ovulation in Natural Cycle-IVF?
Status: UNKNOWN
Conditions: Ovulation|Ovulation Inhibition|Ovulation Inhibition/Drug Effects|Pregnancy|Fertilization in Vitro/Methods
Interventions: DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Studies of Traditional Chinese Medicine Clinical Efficacy Evaluation Index
Status: COMPLETED
Conditions: Coronary Heart Disease|Stable Angina Pectoris
Interventions: DRUG: Louxiangdan Tongxin granules|DRUG: TCM granules placebo|DRUG: Chixiangshen Tongxin granules|DRUG: TCM granule placebo plus western basis treatment|DRUG: Western basis treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Evaluation of the Effect of CGF in Promoting Mechanical-stretch Induced in Vivo Skin Regeneration
Status: UNKNOWN
Conditions: Scar
Interventions: PROCEDURE: CGF injection|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CH-EUS in Diagnosis of Inoperable Bile Duct Tumors
Status: UNKNOWN
Conditions: Inoperable Disease|Bile Duct Cancer
Interventions: PROCEDURE: Endoscopic ultrasound with fine needle biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Art Therapy on Brain Connectivity in Recent Post-Stroke Aphasia
Status: RECRUITING
Conditions: Ischemic or Hemorrhagic Stroke
Interventions: OTHER: Art therapy and standard orthophonic rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VACuum-Assisted Closure for Necrotizing Soft Tissue infecTIONs
Status: NOT_YET_RECRUITING
Conditions: Necrotising Soft Tissue Infections
Interventions: OTHER: Negative pressure wound therapy (NPWT)|OTHER: Conventional dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ONC-392 Plus Lutetium Lu 177 Vipivotide Tetraxetan in Patients With mCRPC
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: ONC-392|DRUG: lutetium Lu 177 vipivotide tetraxetan, IV infusion, Q6W for up to 6 doses.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetics (PK) Study to Investigate the Effect of Rifampin on PK of Vemurafenib (Zelboraf)
Status: COMPLETED
Conditions: Malignant Melanoma, Neoplasms
Interventions: DRUG: Rifampin|DRUG: Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Blood Flow Through IPAVA and PFO Related to Breath-hold and SCUBA Diving-induced Pulmonary Hypertension?
Status: COMPLETED
Conditions: Patent Foramen Ovale|Intrapulmonary Arteriovenous Anastamosis
Interventions: DRUG: Sildenafil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy, Safety and Tolerability of Secukinumab in Patients With Rheumatoid Arthritis Taking Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: secukinumab (AIN457)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics and Tolerability of Tacrolimus in Kidney Transplant Recipients.
Status: UNKNOWN
Conditions: Kidney Transplant
Interventions: DRUG: tacrolimus tablet|DRUG: tacrolimus capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of One Dosage of Paliperidone Extended Release (ER) in Treating Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone ER|DRUG: Placebo|DRUG: Paliperidone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Access HIV Ag/Ab Combo Assay - European Union (EU) Clinical Trial Protocol
Status: COMPLETED
Conditions: HIV I Infection|HIV-2 Infection
Interventions: DIAGNOSTIC_TEST: Access HIV_blood donor|DIAGNOSTIC_TEST: Access HIV_Hospitalized patient|DIAGNOSTIC_TEST: Access HIV_known HIV-1 antibody positives|DIAGNOSTIC_TEST: Access HIV_known HIV-2 antibody positives|DIAGNOSTIC_TEST: Access HIV_known HIV-1 p24 Ag positive|DIAGNOSTIC_TEST: Access HIV_Canada's requirements_Blood donor|DIAGNOSTIC_TEST: Access HIV_Canada's requirements_HIV positive|DIAGNOSTIC_TEST: Access HIV_Canada's requirements_P24 Positive
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Study Comparing Ferric Carboxymaltose to Iron Sucrose to Treat Fe Deficiency in the Surgically Critically Ill
Status: WITHDRAWN
Conditions: ICU Anemia|Functional Iron Deficiency
Interventions: DRUG: Ferric carboxymaltose|DRUG: Iron sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carfilzomib Thalidomide and Dexamethasone in Patients With Relapsed and/or Refractory Multiple Myeloma
Status: UNKNOWN
Conditions: Relapsed and/or Refractory Multiple Myeloma
Interventions: DRUG: Carfilzomib, Thalidomide and Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Coadministered Erythromycin on the Pharmacokinetics and Safety of Padsevonil
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Padsevonil (UCB0942)|DRUG: Erythromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fish Oil Supplementation in Women With Gestational Diabetes
Status: UNKNOWN
Conditions: Fetal Macrosomia|Congenital Abnormality|Other Respiratory Problems After Birth
Interventions: DIETARY_SUPPLEMENT: Fish oil, Ocean plus|DIETARY_SUPPLEMENT: Sunflower Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Effectiveness of Existing Anti vascUlar Endothelial Growth Factor (Anti VEGF) in Patients With Wet Age-related Macular Degeneration (wAMD) (AURA)
Status: COMPLETED
Conditions: Ophthalmology, Macular Degeneration
Interventions: DRUG: Ranibizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ozone Therapy for the Home Oral Hygiene of the Pregnant Woman.
Status: UNKNOWN
Conditions: Pregnancy Gingivitis|Ozone
Interventions: DEVICE: Ozonated water delivering device effects on the oral health of pregnant women|BEHAVIORAL: Oral hygiene instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Mid-Transverse Process to Pleura (MTP) Block and Intrathecal Morphine in Idiopathic Scoliosis Patients Undergoing Posterior Spinal Fusion
Status: RECRUITING
Conditions: Mid-Transverse Process Block|Intrathecal Morphine|Idiopathic Scoliosis|Posterior Spinal Fusion
Interventions: DEVICE: Ultrasound-Guided Mid-Transverse Process to Pleura (MTP) Block|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ph 1 ADI-PEG 20 Plus Doxorubicin; Patients With HER2 Negative Metastatic Breast Cancer
Status: COMPLETED
Conditions: HER2 Negative Metastatic Breast Cancer
Interventions: DRUG: ADI-PEG 20
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of Lingual Frenotomy in Newborns With Simultaneous Lip Tie for the Relief of Breastfeeding Pain.
Status: COMPLETED
Conditions: Ankyloglossia|Breast Feeding|Enlarged Labial Frenum
Interventions: PROCEDURE: Lingual Frenotomy|PROCEDURE: Labial Frenotomy|PROCEDURE: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sirolimus-Eluting Stent Versus Standard Stent in Diabetic
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Drug eluting stent|DEVICE: Bare metal stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Efficacy and Safety of Ivonescimab Combined With Irinotecan Liposome as Second-line Regimen for ES-SCLC
Status: NOT_YET_RECRUITING
Conditions: Extensive-stage Small-cell Lung Cancer
Interventions: DRUG: ivonescimab|DRUG: irinotecan liposome
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The S.M.A.R.T. Project: Stress Management and Resilience Training for Teens
Status: COMPLETED
Conditions: Depression Mild|Resilience, Psychological|Adolescent Behavior
Interventions: BEHAVIORAL: MFY|BEHAVIORAL: HLG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of the CYP2C19 Polymorphism in Helicobacter Pylori Eradication
Status: COMPLETED
Conditions: CYP2C19 Polymorphism|H.Pylori Infection|Therapy
Interventions: DRUG: amoxicillin clarithromycin omeprazole 1|DRUG: amoxicillin clarithromycin omeprazole 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of Low Power Laser Therapy on Muscle Performance Isokinetic Pre-exercise in Individuals With Diabetes Mellitus Type II
Status: SUSPENDED
Conditions: Diabetes Mellitus Non-insulin-dependent
Interventions: OTHER: Low level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RF Applications for Residual LAA Leaks
Status: UNKNOWN
Conditions: Left Atrial Appendage Thrombosis|Stroke, Ischemic|Atrial Fibrillation
Interventions: PROCEDURE: Radiofrequency Energy Applications
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Inferiority Trial Comparing Eurofarma's Experimental Product Saccharomyces Boulardii Versus Floratil® in the Prevention of Antibiotic-Associated Diarrhea
Status: WITHDRAWN
Conditions: Antibiotics
Interventions: OTHER: Probiotic|OTHER: Probiotic|OTHER: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Safety and Efficacy of BOL-303242-X Ophthalmic Suspension in Dry Eye Syndrome
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DRUG: 0.3% BOL-303242-X ophthalmic suspension|DRUG: 2% BOL-303242-X ophthalmic suspension|DRUG: Placebo Comparator: Vehicle|DRUG: 1% BOL-303242-X ophthalmic suspension|DRUG: 2% BOL-303242-X ophthalmic suspension AM|DRUG: 2% BOL-303242-X ophthalmic suspension PM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development of a Marker of Adherence for Tracking Consumption of Nutrient Supplements
Status: COMPLETED
Conditions: Adherence, Treatment
Interventions: DIETARY_SUPPLEMENT: lipid-based nutrient supplement containing adherence markers|DIETARY_SUPPLEMENT: lipid-based nutrient supplement containing or not containing adherence markers|DIETARY_SUPPLEMENT: lipid-based nutrient supplement not containing adherence markers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Effect of Intraaricular Knee Injections of Hyaluronic Acid (HA) on Bone and Cartilaginous Debris, as a Therapeutic Indicator
Status: UNKNOWN
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Sodium hyaluronate (hyaluronic acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: ECT
Clinical trial: Novel MRI Techniques for the Characterization and Treatment Assessment of High Grade Brain Lesions
Status: COMPLETED
Conditions: Brain Neoplasm|Lymphoma|Metastatic Malignant Neoplasm in the Brain|Recurrent Malignant Brain Neoplasm
Interventions: DRUG: Gadobenate Dimeglumine|DRUG: Gadobutrol|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Information and Communication Technology Based Centralized Clinical Trial Monitoring System for Insulin Dose Adjustment
Status: COMPLETED
Conditions: Diabetes Mellitus|Insulin Hypoglycemia|Insulin-dependent Diabetes Mellitus
Interventions: DEVICE: Algorithm-based feedback messages|DEVICE: Personal Health Record
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FKBP5 Methylation and Childhood Emotional Abuse in Complex Posttraumatic Stress Disorder: Investigating the Relationship and Its Predictive Role in Therapy Outcome
Status: COMPLETED
Conditions: Borderline Personality Disorder|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Dialectical behavioral therapy for the treatment of posttraumatic stress disorder (DBT-PTSD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tau PET Imaging With 18F-AV-1451 in Subjects With MAPT Mutations
Status: COMPLETED
Conditions: Frontotemporal Lobar Degeneration (FTLD)|Frontotemporal Dementia (FTD)|Tauopathies
Interventions: DRUG: 18F-AV-1451
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Intraoperative Clonidine for Prevention of Postoperative Agitation in Pedriatic Anesthesia With Sevoflurane.
Status: COMPLETED
Conditions: Is an Only Child
Interventions: DRUG: Clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Influence of Low Frequency Repetitive Transcranial Stimulation (r-TMS) on Motor and Cognitive Measurements in Patients With Asymmetric Parkinson's Disease
Status: UNKNOWN
Conditions: UPDRS
Interventions: DEVICE: repetitive transcranial stimulation (r-TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ondansetron vs Ondansetron Plus Dexamethasone for Relieving Intrathecal Morphine Side Effects After C-section
Status: COMPLETED
Conditions: Pruritus|Cesarean Section
Interventions: DRUG: Ondansetron (Zofran)|DRUG: Dexamethasone (Decadron)|OTHER: Spinal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: LEVANT 2 Safety Registry
Status: COMPLETED
Conditions: Peripheral Artery Disease|Femoropopliteal Artery Occlusion|Femoropopliteal Stenosis
Interventions: DEVICE: Lutonix Drug Coated Balloon|DEVICE: Standard PTA Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of a Medication Adherence Smartphone Application on Medication Adherence in Chronic Illness
Status: COMPLETED
Conditions: Medication Adherence|Self Efficacy
Interventions: BEHAVIORAL: Medisafe smartphone mobile application|BEHAVIORAL: Printed medication list
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Acceptance, Safety, and Efficacy of MadaJet Versus Needle Injection for Sperm Retrieval in Patients With Azoospermia
Status: COMPLETED
Conditions: Male Infertility
Interventions: PROCEDURE: Madajet|PROCEDURE: Needle injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors
Status: COMPLETED
Conditions: Retinoblastoma|Clear Cell Sarcoma|Renal Cell Carcinoma|Rhabdoid Tumor|Wilms Tumor|Hepatoblastoma|Neuroblastoma|Germ Cell Tumors|Ewings Sarcoma|Non-rhabdomyosarcoma Soft Tissue Sarcoma|Osteosarcoma|Rhabdomyosarcoma
Interventions: DRUG: Simvastatin|DRUG: Cyclophosphamide|DRUG: Topotecan|DRUG: Myeloid growth factor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adductor Canal Block and Multimodal Local Infiltration Analgesia in Patients Receiving Total Knee Arthroplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Arthroplasty, Replacement, Knee|Analgesia|Rehabilitation
Interventions: OTHER: Pain scores (numerical rating scale at rest and motion)|OTHER: Secondary outcomes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tarceva (Erlotinib) in First Line in Patients With Locally Advanced or Metastatic Lung Adenocarcinoma With EGFR Mutations
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: erlotinib [Tarceva]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of a Biological Mesh (StratticeTM) for the Prevention of Parastomal Hernia After Colorectal Surgery With Colostomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Parastomal Hernia|Terminal Colostomy
Interventions: DEVICE: strattice|PROCEDURE: No strattice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Manufacturing Transfer Study Comparing the Bioequivalence of a Single Oral Dose of Claritin-D 12-Hour Extended Release Tablet From 2 Different Manufactuers Under Fed Conditions in Healthy Adult Subjects
Status: COMPLETED
Conditions: Clinical Pharmacology
Interventions: DRUG: Loratadine + Pseudoephedrine sulfate (Claritin-D, BAY818725) (Manufacturer-SAG)|DRUG: Loratadine + Pseudoephedrine sulfate (Claritin-D, BAY818725) (Manufacturer-Heist)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Understanding the Effects of Quantitatively-Prescribing Passive-Dynamic Ankle-Foot Orthosis Bending Stiffness for Individuals Post-Stroke
Status: COMPLETED
Conditions: Gait, Hemiplegic
Interventions: DEVICE: Ankle Orthotic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Deep Neuromuscular Blockade in Strabismus Surgery
Status: NOT_YET_RECRUITING
Conditions: Strabismus
Interventions: OTHER: moderate to deep neuromuscular blockade|OTHER: shallow to minimal neuromuscular blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Vital Signs to Identify, Target, and Assess Level (VITAL) Care Study III
Status: COMPLETED
Conditions: Cardiac Arrest|Renal Failure|Respiration Failure|Myocardial Infarction|Severe Sepsis
Interventions: DEVICE: Automatic RR Measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial of Multiple-doses of Aripiprazole in Adults With Schizophrenia or Bipolar 1 Disorder
Status: COMPLETED
Conditions: Schizophrenia|Bipolar I Disorder
Interventions: DRUG: Aripiprazole|DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Generic Leflunomide 20 mg Film-coated Tablets and Reference Product Under Fasting Conditions
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteer
Interventions: DRUG: Leflunomide 20 mg Film-coated Tablet|DRUG: ARAVA® 20 mg Film-coated Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of COVID-19 Outbreak on the Alcohol Consumption in Patients With Alcohol-related Liver Disease (ICoLD)
Status: UNKNOWN
Conditions: Alcohol-related Liver Disease|Alcohol Dependence|Alcohol Withdrawal|Addiction, Alcohol
Interventions: DIAGNOSTIC_TEST: Study questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Response-based Treatment of High-risk Neuroblastoma
Status: UNKNOWN
Conditions: Newly Diagnosed High Risk Neuroblastoma
Interventions: DRUG: Cisplatin|DRUG: Doxorubicin|DRUG: Etoposide|DRUG: Cyclophosphamide|DRUG: Ifosfamide|DRUG: Carboplatin|PROCEDURE: Tandem HDCT/auto-SCT|RADIATION: Radiotherapy|DRUG: Interleukin-2|DRUG: Isotretinoin|RADIATION: MIBG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT