pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Quality of Life and Survivorship Care in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
Status: COMPLETED
Conditions: Advanced Malignant Mesothelioma|Carcinoma of the Appendix|Ovarian Sarcoma|Ovarian Stromal Cancer|Pseudomyxoma Peritonei|Recurrent Colon Cancer|Recurrent Malignant Mesothelioma|Recurrent Ovarian Epithelial Cancer|Recurrent Ovarian Germ Cell Tumor|Stage III Colon Cancer|Stage III Ovarian Epithelial Cancer|Stage III Ovarian Germ Cell Tumor|Stage IV Colon Cancer|Stage IV Ovarian Epithelial Cancer|Stage IV Ovarian Germ Cell Tumor|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: BEHAVIORAL: HIPEC Orientation|BEHAVIORAL: Consultation with Survivorship Navigator|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Imatinib Mesylate in Treating Patients With Gastrointestinal Stromal Tumor That Has Been Completely Removed During Surgery
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumor
Interventions: DRUG: imatinib mesylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venous Ethanol for Ventricular Tachycardia
Status: RECRUITING
Conditions: Ventricular Tachycardia|Ischemic Cardiomyopathy
Interventions: DRUG: Venous ethanol|PROCEDURE: Catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 3rd/4th Line Placebo-controlled Trial of Sorafenib in Patients With Predominantly Non Squamous Non-Small Cell Lung Cancer (NSCLC).
Status: COMPLETED
Conditions: Carcinoma|Non-Small-Cell Lung
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of Esomeprazole and the Effect of Food on the Pharmacokinetics of Balovaptan in Healthy Volunteers
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: Balovaptan|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening for Lung Cancer in Current or Past Smokers With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Lung Cancer|Precancerous Condition
Interventions: OTHER: cytology and cytometry specimen collection procedure|OTHER: Chest x ray|PROCEDURE: Autofluorescence bronchoscopy|PROCEDURE: CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Pilot Study of a Novel 532nm KTP Laser for the Treatment of Fresh Surgical Scars
Status: COMPLETED
Conditions: Scar|Surgical Scar|Cicatrix|Cicatrix, Hypertrophic|Keloid
Interventions: DEVICE: 532nm KTP|DEVICE: 595nm PDL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of HRS-7535 Tablets in Obese Subjects .
Status: NOT_YET_RECRUITING
Conditions: Overweight and Obesity
Interventions: DRUG: HRS-7535;Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: STUDY TO ASSESS THE LONG-TERM SAFETY OF EXTINA (KETOCONAZOLE) FOAM, 2%
Status: COMPLETED
Conditions: Dermatitis, Seborrheic
Interventions: DRUG: Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lasers as an Alternative to Formocresol and Sodium Hypochlorite Medicaments in Pulpotomy Techniques
Status: COMPLETED
Conditions: Pulp Disease, Dental|Pulp Mummification
Interventions: DRUG: Formocresol|DRUG: Sodium Hypochlorite Solution|DEVICE: Diode laser|DEVICE: Er,Cr:YSGG laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Sub Study of the Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant in Patients With Presumed Nonalcoholic Steatohepatitis (NASH)
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis (NASH)
Interventions: OTHER: MRI-PDFF
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of NIVO Plus IPI and Guadecitabine or NIVO Plus IPI in Melanoma and NSCLC Resistant to Anti-PD1/PDL1
Status: NOT_YET_RECRUITING
Conditions: Melanoma|Non Small Cell Lung Cancer
Interventions: DRUG: Ipilimumab plus nivolumab plus guadecitabine|DRUG: Ipilimumab plus nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study to Evaluate MT-6548 in Hemodialysis Subjects Not Receiving ESAs With Anemia Associated With Chronic Kidney Disease in Japan
Status: COMPLETED
Conditions: Anemia; Hemodialysis Dependent Chronic Kidney Disease
Interventions: DRUG: MT-6548
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study To Evaluate Efficacy And Safety Of A Fixed Combination Therapy Of Amlodipine And Atorvastatin
Status: COMPLETED
Conditions: Hypertension|Hypercholesterolemia
Interventions: DRUG: Amlodipine 2.5mg/Atorvastatin 5mg|DRUG: Amlodipine 2.5mg/Atorvastatin 10mg|DRUG: Amlodipine 5mg/Atorvastatin 5mg|DRUG: Amlodipine 5mg/Atorvastatin 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-In-Human Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ALT-100
Status: COMPLETED
Conditions: ARDS, Human
Interventions: DRUG: ALT-100|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the Effects of GnRHa Add up to Routine Luteal Phase Support on Frozen Embryo Implantation in Frozen Embryo Transfer .
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: triptorelin 0.1|DRUG: E2|DRUG: Progesterone|DRUG: triptorelin 3.75mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concentration of Receptors With Affinity for Cannabidiol and Cannabinol and the Effect on Chronic Orofacial Pain of Muscle Origin
Status: ENROLLING_BY_INVITATION
Conditions: Myalgia|Muscle Pain|Orofacial Pain|Headache, Tension|Headaches Muscular
Interventions: DIAGNOSTIC_TEST: Blood CB1, CB2, TRPV-1 concentration measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gastric Volume After Drinking 175 ml of Ice Water Prior to Gastroscopy in Healthy Adult Patients
Status: COMPLETED
Conditions: Fasting|Perioperative Pulmonary Aspiration
Interventions: OTHER: Ice water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Confirmatory Efficacy of the Building a Strong Identity and Coping Skills Program
Status: NOT_YET_RECRUITING
Conditions: Chronic Stress|Anxiety|Depression
Interventions: BEHAVIORAL: Building a Strong Identity and Coping Skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neural Correlates of Ketamine's Anti-suicidal Effects in Bipolar Depression
Status: RECRUITING
Conditions: Bipolar Disorder (BD)|Suicidality
Interventions: DRUG: Intravenous Ketamine (IV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antihypertensive Therapy in Patients With Comorbidities
Status: UNKNOWN
Conditions: Adherence to Personalized EBM Antihypertensive Drug Prescriptions for Patients With Hypertension and Comorbidities in Everyday Clinical Practice
Interventions: DRUG: antihypertensive therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot Study of Empagliflozin in the Treatment of Acromegalic Cardiomyopathy
Status: UNKNOWN
Conditions: Acromegaly|Cardiomyopathies
Interventions: DRUG: Empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Chan-Chuang Qigong With Breathing Meditation on Quality of Life in Patients With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Quality of Life|Intraoperative Awareness
Interventions: OTHER: qigong
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ELEVATE Early LEvosimendan Vs Usual Care in Advanced Chronic hearT failurE
Status: TERMINATED
Conditions: Advanced Chronic Heart Failure
Interventions: DRUG: Diuretics|DRUG: Levosimendan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PTED Versus Radiofrequency Ablation for Lumbar Disc Herniation
Status: UNKNOWN
Conditions: Lumbar Disc Herniation|Chronic Low Back Pain
Interventions: PROCEDURE: Percutaneous transforaminal endoscopic discectomy|PROCEDURE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficiency of Newly Designed Prefabricated PMMA Crowns for Restoring Primary Teeth in Comparison to Stainless Steel and Zirconia Crowns
Status: COMPLETED
Conditions: Decay, Dental
Interventions: OTHER: PMMA crowns
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Feasibility, Potential Efficacy, and Experiences of Using a Group-based Acceptance and Commitment Therapy Among Older People With Chronic Low Back Pain
Status: RECRUITING
Conditions: Chronic Low-back Pain
Interventions: BEHAVIORAL: Acceptance and commitment therapy (ACT)|BEHAVIORAL: back exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study Comparing the Safety and Tolerance of SMOFlipid 20% in Long-term Treatment With Parenteral Nutrition
Status: COMPLETED
Conditions: Parenteral Nutrition
Interventions: DRUG: SMOF lipid and Intralipid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of DCVax-Direct in Solid Tumors
Status: UNKNOWN
Conditions: Locally Advanced Tumor|Metastatic Solid Tissue Tumors|Liver Cancer|Colorectal Cancer|Pancreatic Cancer|Melanoma
Interventions: BIOLOGICAL: DCVax-Direct
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Sativex® for Relief of Spasticity in Subjects With Multiple Sclerosis.
Status: COMPLETED
Conditions: Spasticity|Multiple Sclerosis
Interventions: DRUG: Sativex®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Endoscopic Submucosal Dissection Versus Laparoscopic Resection for Early Colorectal Neoplasms
Status: UNKNOWN
Conditions: Colorectal Neoplasms
Interventions: PROCEDURE: Endoscopic submucosal dissection|PROCEDURE: Laparoscopic resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotype Threat Effect on CPR Performance in Covid-19 Intensive Care Units: A Randomised Controlled Mannequin Study
Status: COMPLETED
Conditions: Stereotype-threat|COVID-19
Interventions: OTHER: stereotype threat manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Explore the Pharmacodynamic Changes When Transitioning From Rivaroxaban to Warfarin in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rivaroxaban|DRUG: Warfarin|DRUG: Vitamin K|DRUG: Vitamin K|DRUG: Warfarin|DRUG: Warfarin|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BIA 5-1058
Status: COMPLETED
Conditions: Cardiovascular Disease+Pulmonary Disease|Pulmonary Arterial Hypertension
Interventions: DRUG: BIA 5-1058|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin K2 (MK7) on Cardiovascular and Bone Disease in Dialysis Patients
Status: COMPLETED
Conditions: Vitamin K Supplementation|Endstage Renal Disease|Cardiovascular Disease|Bone Disease
Interventions: DIETARY_SUPPLEMENT: Vitamin K2 (MK7)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine as Steroid-Sparing Agent in Pulmonary Sarcoidosis (HySSAS).
Status: COMPLETED
Conditions: Pulmonary Sarcoidosis
Interventions: DRUG: Prednisone|DRUG: Hydroxychloroquine + Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Oral Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) Compared to Intravenous Imipenem-cilastatin in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)
Status: RECRUITING
Conditions: Urinary Tract Infection|Acute Pyelonephritis
Interventions: DRUG: TBP-PI-HBr|DRUG: Imipenem-cilastatin|DRUG: Dummy Infusion|DRUG: Dummy Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Surufatinib Plus Sintilimab Combined With Chemotherapy in the Treatment of Advanced Gastric Neuroendocrine Carcinoma
Status: RECRUITING
Conditions: Gastric Neuroendocrine Carcinoma
Interventions: DRUG: Sintilimab，Surufatinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Previously Placed Nephrostomy Tract (NT) Versus Single Stage Percutaneous Nephrolithotomy (PCNL)
Status: TERMINATED
Conditions: Urolithiasis
Interventions: PROCEDURE: NT 1 day before PCNL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lithium for Suicidal Behavior in Mood Disorders
Status: TERMINATED
Conditions: Depressive Disorder|Bipolar Disorder|Suicide|Suicide, Attempted
Interventions: DRUG: Lithium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Project FLUx COntact-CoVID-19 Faculty of Medicine Paris-Saclay
Status: COMPLETED
Conditions: Covid19
Interventions: OTHER: Antigenic tests (on saliva samples)|OTHER: Individual electronic sensor port|OTHER: Atmospheric measurements of CO2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Methods for Increasing Genetic Testing Uptake in Michigan
Status: RECRUITING
Conditions: Breast Cancer|Colorectal Cancer|Ovarian Cancer|Prostate Cancer|Pancreatic Cancer|Endometrial Cancer|History of Cancer
Interventions: OTHER: Publicly available genetic testing resources|BEHAVIORAL: Virtual genetics navigator|BEHAVIORAL: Motivational interviewing (MI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Trial to Assess the Efficacy and Safety of Inhaled AQ001S in the Management of Acute COVID-19 Symptoms
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: Drug, inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ImmunoCARE: Rapid, Accurate COVID Testing to Reduce Hospitalization of Immunocompromised Individuals
Status: ACTIVE_NOT_RECRUITING
Conditions: Immunodeficiency|Immunosuppression|HIV Infections|Graft Versus Host Disease|Leukemia|Lymphoma|Cancer|Multiple Myeloma|Transplant|Age-Related Immunodeficiency
Interventions: OTHER: Access to Cue Health COVID-19 Remote testing and treatment for COVID-19
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Value of Using Platelet Rich Plasma After Hysteroscopic Lysis of Severe Intrauterine Adhesions
Status: COMPLETED
Conditions: Intrauterine Adhesion
Interventions: BIOLOGICAL: Platelet Rich Plasma|DEVICE: Intrauterine Foley's Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Stepped-wedge Cluster Randomized Controlled Trial for Evaluating an Intervention in Patients With Stroke Tailored Education in Addition to Physiotherapist Treatment
Status: WITHDRAWN
Conditions: Stroke
Interventions: OTHER: Multimodal intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Synchronized Lifestyle Modification Program on Diabetic Neuropathy Taking Oral Hypoglycemics
Status: UNKNOWN
Conditions: Diabetic Neuropathies
Interventions: OTHER: SLP|OTHER: SLP along with Physiotherapy|OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Long-Term Smoking Abstinence Among Cervical Cancer Survivors (Project ACCESS)
Status: RECRUITING
Conditions: Smoking Cessation|Cervical Cancer|High Grade Cervical Dysplasia
Interventions: BEHAVIORAL: Smoking Cessation treatment delivered by Tobacco Free Florida Quitline|DRUG: Nicotine patch|DRUG: Nicotine Lozenge|BEHAVIORAL: Motivation and Problem Solving (MAPS) intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Implementation of Nurse-guided Web-based Cognitive Behavioral Therapy for Pain Management
Status: COMPLETED
Conditions: Chronic Musculoskeletal Pain
Interventions: BEHAVIORAL: Nurse-guided Web-based Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: XH001 Combination With Ipilimumab and Chemotherapy for Patients With Resected Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: XH001|DRUG: Ipilimumab Injection|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of PMcardio AI-assisted Clinical Assistant in Primary Care
Status: COMPLETED
Conditions: Cardiovascular Diseases|Medical Device|Primary Health Care|Electrocardiogram|Dyspnea|Chest Pain|Syncope|Breath Shortness|General Practitioner
Interventions: DEVICE: AI-assisted Clinical Assistant PMcardio
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study for Palliation of Pain in Bone Metastases by MR-HIFU
Status: COMPLETED
Conditions: Secondary Malignant Neoplasm of Bone
Interventions: DEVICE: High Intensity Focused Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Feasibility Study of Autologous Bone Marrow Cell Transplantation in Patients With Peripheral Arterial Occlusive Disease (PAOD)
Status: COMPLETED
Conditions: Arterial Occlusive Diseases
Interventions: PROCEDURE: intraarterial stem cell therapy|OTHER: Stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Ketamine in Patients Undergoing Hysteroscopic Endometrial Thermal Ablation Surgery
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Group A: Saline Group|DRUG: Group B: 1% Ketamine group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized, Double-Blind Phase 1 Safety and Tolerability Study of Pafuramidine Maleate (DB289) in Healthy Subjects
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: pafuramidine maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Cohort 2 Efficacy of Nasopharyngeal Ventilation With Endotracheal Tube for Surgery
Status: COMPLETED
Conditions: General Anesthesia With Endotracheal Intubation in Surgery
Interventions: OTHER: Mask then nasopharyngeal|OTHER: Nasopharyngeal then mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Study of Ceftaroline Fosamil/Avibactam in Adults With Augmented Renal Clearance
Status: COMPLETED
Conditions: Augmented Renal Clearance (ARC)|Systemic Inflammatory Response Syndrome (SIRS)
Interventions: DRUG: Ceftaroline fosamil/Avibactam (CXL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Prospective, Long-term, Observational Registry of Pediatric Patients With Inflammatory Bowel Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Crohn's Disease|Ulcerative Colitis|Indeterminate Colitis|Inflammatory Bowel Diseases
Interventions: BIOLOGICAL: Anti TNF therapy including infliximab|DRUG: No Biologics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lifestyle Coaching for Fatigue Mitigation in Emergency Medicine Residents
Status: RECRUITING
Conditions: Lifestyle, Healthy|Sleepiness|Alertness|Shift-Work Related Sleep Disturbance|Work Related Stress|Self Efficacy|Self-Compassion
Interventions: BEHAVIORAL: Personalized lifestyle coaching and educational handout|BEHAVIORAL: Handout
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Randomized Trial of Carotid Artery Stenting With and Without Cerebral Protection
Status: COMPLETED
Conditions: Carotid Artery Stenosis
Interventions: DEVICE: CAS with cerebral protection|DEVICE: CAS without cerebral protection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effisayil™ ON: A Study to Test Long-term Treatment With Spesolimab in People With Generalized Pustular Psoriasis Who Took Part in a Previous Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Generalized Pustular Psoriasis
Interventions: DRUG: Spesolimab|DRUG: Spesolimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Intravascular Injection Between Blunt and Sharp Needles During Cervical Transforaminal Epidural Block.
Status: COMPLETED
Conditions: Pain|Radicular; Neuropathic, Cervical
Interventions: PROCEDURE: block with Blunt-type block needle.|PROCEDURE: block with sharp-type block needle.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Study of BBI503 in Adult Patients With Advanced Urologic Malignancies
Status: WITHDRAWN
Conditions: Urologic Malignancies|Renal Cell Carcinoma|Urothelial Carcinoma
Interventions: DRUG: BBI503
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Vapocoolant Spray and EMLA Cream on Pain During Needle Electromyography
Status: COMPLETED
Conditions: Electrodiagnosis
Interventions: DEVICE: vapocoolant spray|DRUG: topical anesthetic cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Of The Mechanism Of Action Of CP-690,550 In The Skin Of Subjects With Moderate To Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: (CP-6890,550) Tofacitinib|DRUG: Placebo|DRUG: (CP-690,550) Tofacitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Outpatients With Severe Asthma and Moderate or Severe Major Depressive Disorder
Status: COMPLETED
Conditions: Severe Asthma|Moderate or Severe Major Depressive Disorder
Interventions: DRUG: Placebo|DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Apatinib Combine With Platinum-Based Doublet Chemotherapy for First-line Treatment of Advanced NSCLC
Status: UNKNOWN
Conditions: Lung Cancer|Non Small Cell Lung Cancer|Combination Chemotherapy|Apatinib
Interventions: DRUG: Apatinib|DRUG: AP or AC|DRUG: Apatinib 250mg|DRUG: Apatinib 500mg|DRUG: Apatinib 750mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Multiple-dose of Gamma-secretase Inhibitor in Healthy Male Japanese and Healthy Elderly Japanese
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BMS-708163|DRUG: BMS-708163|DRUG: BMS-708163|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Squamous Cell of Head and Neck|Oropharynx Squamous Cell Carcinoma
Interventions: DRUG: Nivolumab Injection|RADIATION: Radiotherapy (RT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zotarolimus and Everolimus-Eluting Stents ProsPectively Compared in Real World
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Endeavor Resolute Stent|DEVICE: Xience V Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Oxytocin in Autism to Improve Reciprocal Social Behaviors
Status: COMPLETED
Conditions: Autism Spectrum Disorders
Interventions: DRUG: Double blind phase Placebo Nasal Spray|DRUG: double Blind Oxytocin Nasal Spray|DRUG: Open Label intranasal oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Mindfulness Based Stress Reduction Intervention in Patients With Non-alcoholic Fatty Liver Disease
Status: WITHDRAWN
Conditions: Non-Alcoholic Fatty Liver Disease|Fatty Liver, Nonalcoholic|Obesity
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction (MBSR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Pathophysiology of Status Epilepticus and Dysimmune Encephalitis
Status: RECRUITING
Conditions: Status Epilepticus|Dysimmune Encephalopathy
Interventions: OTHER: Blood sampling, cerebrospinal fluid , post-mortem cerebral tissues (NA for the Group 3)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stimulating Fiber Intake Via Personalized Dietary Advice
Status: COMPLETED
Conditions: Dietary Habits|Dietary Fiber|Personalized Advice|Microbiota
Interventions: BEHAVIORAL: PDA|OTHER: Control (no intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Ischemic Postconditioning on Microvascular Obstruction in Reperfused Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: PROCEDURE: Primary angioplasty|PROCEDURE: Postconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Buprenorphine/Naloxone Dose on Experimental Stress Reactivity and Opioid Abstinence
Status: COMPLETED
Conditions: Heroin Dependence|Opioid Use Disorder
Interventions: DRUG: Extended release morphine|DRUG: Buprenorphine/Naloxone low dose|DRUG: Buprenorphine/Naloxone moderate dose|DRUG: Buprenorphine/Naloxone high dose|DRUG: Active stressor|DRUG: Placebo stressor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Botulinum Toxin A (Botox) in Tissue Expander Breast Reconstruction
Status: COMPLETED
Conditions: Breast Cancer|Pain, Postoperative|BRCA1 Mutation|BRCA2 Mutation|Breast Diseases|Neoplasms
Interventions: DRUG: Botulinum Toxin Type A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mobilization Immediate After Abdominal Surgery
Status: COMPLETED
Conditions: Respiratory Insufficiency|Postoperative Pulmonary Complications
Interventions: PROCEDURE: Mobilisation|PROCEDURE: Mobilisation and breathing exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Combination of Trastuzumab and Ixabepilone Versus Trastuzumab and Docetaxel in Patients With Advanced and/or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: ixabepilone|DRUG: docetaxel|DRUG: trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adapted Physical Activity to Promote Quality of Life, Well-being and Physical Activity Levels in Pregnant Women (WELL-DONE!Study)
Status: UNKNOWN
Conditions: Pregnant Women
Interventions: OTHER: Adapted physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Artificial Intelligence Algorithms for Discriminating Between COVID-19 and Influenza Pneumonitis Using Chest X-Rays
Status: UNKNOWN
Conditions: COVID-19|Pneumonia, Viral|Influenza With Pneumonia|Flu Symptom|Flu Like Illness|Pneumonia, Interstitial|Pneumonia, Ventilator-Associated|Pneumonia Atypical
Interventions: DIAGNOSTIC_TEST: Scanning Chest X-rays and performing AI algorithms on images
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of A Special Vessel Subtype in Bone Samples From Patients With Osteoporotic and Nonosteoporotic Fracture
Status: UNKNOWN
Conditions: Femoral Neck Fractures
Interventions: PROCEDURE: total hip arthroplasty or proximal femoral nails
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Functional Melatonin Replacement for Sleep Disruptions in Individuals With Tetraplegia
Status: COMPLETED
Conditions: Insomnia|Spinal Cord Injury|Tetraplegia|Sleep Disorders
Interventions: DRUG: Ramelteon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mediterranean Diet Interventions for Eating Behavior and Cognitive Performance Among Older Adults in the Community
Status: COMPLETED
Conditions: Healthy
Interventions: BEHAVIORAL: Mini-flipped Game-based Learning|BEHAVIORAL: Balanced diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of GDC-0919 and Atezolizumab Combination Treatment in Participants With Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: Atezolizumab|DRUG: GDC-0919
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Group Study of the Safety of and Immune Response to a Bird Flu Virus Vaccine (H5N1) in Healthy Adults
Status: COMPLETED
Conditions: Influenza|Virus Diseases
Interventions: BIOLOGICAL: H5N1 (6-2) AA ca Recombinant (A/Hong Kong/213/2003 x A/AnnArbor/6/60 ca)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Colloid Co-hydration and Vasoconstrictor Infusion for Prevention of Hypotension During Cesarean Section
Status: COMPLETED
Conditions: Hypotension Symptomatic|Vasoconstriction|Cesarean Section Complications|Obstetric Anesthesia Problems
Interventions: OTHER: phenylephrine infusion|OTHER: norepinephrine infusion|OTHER: placebo infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Total30 for Astigmatism Contact Lenses
Status: RECRUITING
Conditions: Contact Lens Complication|Astigmatism|Refractive Errors
Interventions: DEVICE: TOTAL30 for Astigmatism Contact Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Multiple Doses of AV-101 in Healthy Volunteers
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: AV-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: the Aorta Arch Stent Graft System Combined With the Endovascular Needle System in Situ Fenestration
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Dissection
Interventions: DEVICE: the Aorta Arch Stent Graft System combined with the Endovascular Needle System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Effectiveness of Virtual Reality-based Dispatcher Assisted Cardiopulmonary Resuscitation Training
Status: RECRUITING
Conditions: Cardiac Arrest
Interventions: BEHAVIORAL: HEROS VR CPR training program|BEHAVIORAL: Conventional HEROS CPR training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Examination of the Bronchoprotective Effect of Endothelin Receptor Blockade in Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: DRUG: Ambrisentan|DRUG: Bosentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HOPE TEAM - Clinical High Risk Group CBSST
Status: WITHDRAWN
Conditions: Prodromal Symptoms|Prodromal Stage|Prodromal States|Psychosis
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacies of Antimicrobial Susceptibility-Guided Versus Empirical Therapy for Rescue Treatment of Helicobacter Pylori Infection
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: two sensitive antibiotics(amoxicillin, clarithromycin, metronidazole, tinidazole, levofloxacin, furazolidone and tetracycline)|DRUG: one proton pump inhibitor, colloidal bismuth pectin|DRUG: two antibiotics based on personal medication history(amoxicillin,levofloxacin, furazolidone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between Preoperative Serum Asprosin Level and Postoperative Analgesic Consumption in Patients Undergoing Caesarean Section
Status: NOT_YET_RECRUITING
Conditions: Obstetric Pain|Cesarean Section|Postoperative Pain
Interventions: OTHER: Measurement Pain Threshold|OTHER: Measurement of Serum Asprosin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Artificial Intelligence to Personalize Prostate Cancer Treatment (the HypoElect Trial)
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Androgen Deprivation Therapy (ADT) - Goserelin|RADIATION: High-Dose-Rate Interstitial Brachytherapy (HDR BRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Platelet Rich Plasma (PRP) on Persistent Olfactory Dysfunction Related to COVID-19
Status: COMPLETED
Conditions: Anosmia|COVID-19
Interventions: DRUG: Platelet rich plasma (PRP)|OTHER: olfactory training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Emergency Suturing With Absorbable Versus Non-absorbable Suture Material in a Pediatric Population
Status: RECRUITING
Conditions: Wounds and Injuries
Interventions: DEVICE: Absorbable|DEVICE: Non absorbable
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Bioequivalence and Adhesion Properties Between Two Granisetron Transdermal Patches.
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Sancuso - Part 1|DRUG: Sancuso - Part 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: the Effect of Doctor-nurse-patient Cooperative Analgesic Linkage Program on Movement Evoked Pain
Status: UNKNOWN
Conditions: Pain, Postoperative|Anaplasia
Interventions: DRUG: Routine Dezocine injection|DRUG: Adjusted Dezocine injection|DRUG: Routine Dynastat or Flurbiprofen Axetil jinjection|DRUG: Adjusted Dynastat or Flurbiprofen Axetil jinjection|OTHER: postoperative rehabilitation|DRUG: normal analgesia pump administration|DRUG: adjusted analgesia pump administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Two Different Norepinephrine Bolus Doses for Management of Spinal Anesthesia-Induced Maternal Hypotension
Status: COMPLETED
Conditions: Spinal Anesthetic Toxicity|Hypotension Drug-Induced|Cesarean Section Complications
Interventions: DRUG: Noradrenaline Bitartrate|DRUG: Bupivacaine Hydrochloride|DRUG: Noradrenaline Bitartrate|DRUG: Bupivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ARC-AAT in Healthy Volunteer Subjects and Patients With Alpha-1 Antitrypsin Deficiency (AATD)
Status: TERMINATED
Conditions: Alpha-1 Antitrypsin Deficiency
Interventions: DRUG: ARC-AAT Injection|OTHER: Placebo|DRUG: Diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Mouthwashes in Reducing Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Viral Load in the Saliva
Status: COMPLETED
Conditions: Covid19|Coronavirus
Interventions: DRUG: Corsodyl® Alcohol free -0.2 % Chlorhexidine digluconate|DRUG: Colgate Peroxyl® -1.5% Hydrogen peroxide|OTHER: Oral-B® Gum & Enamel Care -Cetylpyridinium chloride|OTHER: No rinsing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study of Recombinant Coagulation Factor IX Fc Fusion Protein, BIIB029, in Previously Treated Pediatric Participants With Hemophilia B
Status: COMPLETED
Conditions: Hemophilia B
Interventions: DRUG: rFIXFc|DRUG: FIX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Macular Edema In Patients With Diabetic Retinopathy Undergoing Cataract Surgery
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DRUG: Aflibercept|DRUG: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Compare BMS-936558 to the Physician's Choice of Either Dacarbazine or Carboplatin and Paclitaxel in Advanced Melanoma Patients That Have Progressed Following Anti-CTLA-4 Therapy (CheckMate 037)
Status: COMPLETED
Conditions: Unresectable or Metastatic Melanoma
Interventions: BIOLOGICAL: BMS-936558|DRUG: Dacarbazine|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aerobic Exercises and Gross Motor Function in Spastic Cerebral Palsy
Status: COMPLETED
Conditions: Spastic Cerebral Palsy
Interventions: OTHER: Experimental( Group A ): Aerobic exercises|OTHER: Conventional( Group B): Conventional Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biweekly Follow-Up and At-Home Ultrasound Reduce Anxiety in Women With Recurrent Pregnancy Loss
Status: RECRUITING
Conditions: Recurrent Pregnancy Loss
Interventions: DEVICE: PulseNmore ES™|DEVICE: Standard Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Interleukin-2 in Treating Patients With Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: BIOLOGICAL: aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Preoperative Single Corticosteroid Flash on Morbidity After Colorectal Resection: Monocentric Prospective Pilot Study
Status: TERMINATED
Conditions: Elective Colorectal Surgery
Interventions: DRUG: injection of methylprednisolone at anesthetic induction|BIOLOGICAL: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Switch Study to Evaluate F/TAF in HIV-1 Infected Adults Who Are Virologically Suppressed on Regimens Containing ABC/3TC
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: F/TAF|DRUG: ABC/3TC|DRUG: ABC/3TC Placebo|DRUG: F/TAF Placebo|DRUG: 3rd ARV agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Extension Study Of Leuprolide Acetate (Lupron Depot) In The Treatment Of Central Precocious Puberty
Status: COMPLETED
Conditions: Precocious|Leuprolide Acetate|Luteinizing Hormone (LH)|Gonadotrophin-releasing Hormone Agonist (GnRHa)|Tanner Staging|Depot Formulation|Suppression of LH|Central Precocious Puberty (CPP)|Gonadotrophin-releasing Hormone (GnRH)|Lupron|GnRH Analog|Pediatrics Central Precocious Puberty
Interventions: DRUG: Leuprolide Acetate 3 Month Depot
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Cholesterol- and Cholestanol-Free Diet, Lovastatin, and Chenodeoxycholic Acid for Cerebrotendinous Xanthomatosis
Status: UNKNOWN
Conditions: Cerebrotendinous Xanthomatosis
Interventions: DRUG: chenodeoxycholic acid|DRUG: lovastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Based Stress Reduction for Psycho-socially Vulnerable Pregnant Women.
Status: RECRUITING
Conditions: Perinatal Mental Health|Pregnancy Related
Interventions: BEHAVIORAL: Prenatal mindfulness-based stress reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION