pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Multicenter Trial Comparing One-step Partial Caries Removal to Complete Caries Removal for the Treatment of Deep Carious Lesions in Permanent Teeth. (DECAT : DEep CAries Treatment).
Status: UNKNOWN
Conditions: Deep Caries
Interventions: PROCEDURE: A one-step partial caries removal procedure for the treatment of deep carious lesions in posterior permanent teeth.|PROCEDURE: A complete caries removal procedure for the treatment of deep carious lesions in posterior permanent teeth.|DEVICE: The application of an antibacterial dental adhesive (ClearfilTM SE Protect, Kuraray Dental).|DEVICE: The application of a conventional dental adhesive (ClearfilTM SE Bond, Kuraray Dental)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S0508: Thalidomide and Temozolomide in Treating Patients With Stage IV Melanoma That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: DRUG: temozolomide|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Potential of Orbactiv (Oritavancin) Co-Administered With Warfarin in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Single-Dose IV Oritavancin Diphosphate and Warfarin|DRUG: Single-Dose IV Oritavancin Diphosphate and Warfarin 24 hour post dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining the Efficacy of Fecal Microbiota Transplantation (FMT) and Dietary Fiber in Patients With Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis|Inflammatory Bowel Diseases
Interventions: DRUG: Fecal Microbiota Transplantation|DIETARY_SUPPLEMENT: Psyllium Husk Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of SAB-301 in Healthy Adults
Status: COMPLETED
Conditions: Middle East Respiratory Syndrome Coronavirus
Interventions: BIOLOGICAL: SAB-301|OTHER: Normal (9%) Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Janus Kinase-STAT Inhibition to Reduce APOL1 Associated Kidney Disease
Status: RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: DRUG: Baricitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Effect of Methotrexate (MTX) Dose on Clinical Outcome and Ultrasonographic Signs in Subjects With Moderately to Severely Active Rheumatoid Arthritis (RA) Treated With Adalimumab (MUSICA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Adalimumab|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Using Liquid Biopsy in Newly Diagnosed Patients With High Grade Adenocarcinoma of Ovarian Origin, Fallopian Tubes or Primary Peritoneal
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer
Interventions: OTHER: Diagnostic Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Novel Helmet Design in Patients With Seizures
Status: COMPLETED
Conditions: Drug Resistant Epilepsy|Drop Seizures|Generalized Tonic Clonic Seizure|Complex Partial Seizure|Fall Due to Seizure
Interventions: DEVICE: Hövding inflatable helmet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Better Evidence for Selecting Transplant Fluids
Status: COMPLETED
Conditions: End Stage Kidney Disease|Delayed Graft Function|Kidney Transplant; Complications
Interventions: DRUG: Plasma-Lyte 148 (approx. pH 7.4) IV Infusion|DRUG: 0.9% SODIUM CHLORIDE 9g/L injection BP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Nutritional Strategies or Manual Therapies in Women With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: Mediterranean-diet enriched with a higher dose of tryptophan and magnesium|OTHER: Isocaloric diet|OTHER: Manual therapy|OTHER: Placebo therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Dose Regimen of Intravenous Unfractionated Heparin and Low Molecular Weight Heparin in Critical Ill Patients Versus Critical Ill COVID-19 Patients Using Anti-Xa Levels.
Status: COMPLETED
Conditions: COVID-19|Deep Vein Thrombosis|Anticoagulants and Bleeding Disorders|Critical Illness
Interventions: DRUG: Enoxaparin|DRUG: Heparin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multiple Burrhole Therapy With Erythropoietin for Unstable Moyamoya
Status: COMPLETED
Conditions: Ischemic Attack|Ischemic Stroke|Moyamoya Disease|Burr Hole|Angiogenesis
Interventions: DRUG: erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Gender-Affirming Hormone Therapy Among Transgender Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Transgender Women|HIV/AIDS|Cardiovascular Diseases|Metabolic Disease|Coagulopathy
Interventions: OTHER: Abdominal MR Imaging|OTHER: Cardiac MRI/MRS|OTHER: Oral Glucose Tolerance Testing|OTHER: Whole Body, Lumbar Spine, and Hip DEXA Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Relative Bioavailability and Pharmacodynamics of HSK7653 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HSK7653(5mg)|DRUG: HSK7653(25mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MBCT vs HEP in Patients With Late-Life Depression
Status: NOT_YET_RECRUITING
Conditions: Depression in Old Age|Cognitive Decline
Interventions: BEHAVIORAL: Mindfulness-Based Cognitive Therapy|BEHAVIORAL: Health Enhancement Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pioglitazone and Losartan Provides Additional Renoprotection
Status: COMPLETED
Conditions: Type 2 Diabetes|Diabetic Nephropathy
Interventions: DRUG: pioglitazone+losartan|DRUG: losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Assessment of Radiation-induced Heart Injury in Left-sided Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Heart Injuries|Radiation Toxicity
Interventions: RADIATION: free-breathing|RADIATION: deep inspiratory breath-holding
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Classification and Treatment of Myofascial Headache: a Cross-sectional Study and Randomized Controlled Trial.
Status: RECRUITING
Conditions: Tension-Type Headache|Cervicogenic Headache|Myofascial Headache
Interventions: OTHER: Dry Needling|OTHER: Manual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health Benefits of Functional Meat (With n-3 Fatty Acids and Rosemary Extract) on Low Risk for Cardiovascular Disease People
Status: COMPLETED
Conditions: Low Risk for Cardiovascular Disease
Interventions: OTHER: Functional Meet|OTHER: Control Meat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Screening for Abdominal Aortic Aneurysm and Abdominal Aortic Atherosclerosis by Hand-Held Ultrasonography
Status: COMPLETED
Conditions: Hypertension|Abdominal Aortic Aneurysm|Atheromatosis
Interventions: DEVICE: Ultrasound (Trademark:VScan; Manufacturer:General Electrics)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Well-being in Students and Teachers Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Prosocial Behavior|Community Sense|Optimism|Anxiety|Social Competence|Self-Compassion|Stress, Psychological|Burnout, Professional|Efficacy, Self|Self Awareness
Interventions: BEHAVIORAL: Mindfulness-based social and emotional learning (MBSEL) program for educators|BEHAVIORAL: Mindfulness-based social and emotional learning (MBSEL) program for students
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of The Effect of 980nm Diode Laser Intracanal Irradiation on Levels of Interleukin-8 Expression
Status: COMPLETED
Conditions: Endodontically Treated Teeth
Interventions: DEVICE: Intracanal Diode laser irradiation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of CHF6297 in Healthy Subjects and Patients With COPD
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: CHF6297 (Part 1 - SAD)|DRUG: Placebo (Part 1 - SAD)|DRUG: CHF6297 (Part 2 - MAD)|DRUG: Placebo (Part 2 - MAD)|DRUG: CHF6297 (Part 3)|DRUG: Placebo (Part 3)|DRUG: CHF6297 (Part 4)|DRUG: Placebo (Part 4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About How Itraconazole and Carbamazepine Affect the Level of BAY2927088 in the Blood When These Drugs Are Taken Together by Healthy Participants
Status: COMPLETED
Conditions: Advanced Non-small Cell Lung Cancer|EGFR Mutation|HER2 Mutation|Healthy Volunteers
Interventions: DRUG: BAY2927088|DRUG: Itraconazole|DRUG: Carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treatment of Exercise-Induced Pulmonary Vascular Dysfunction After Pulmonary Thromboendarterectomy or Balloon Pulmonary Angioplasty
Status: RECRUITING
Conditions: Chronic Thromboembolic Disease (CTED)|Exercise Intolerance Post PEA Surgery
Interventions: DRUG: Adempas
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Furocyst in Patients With Poly Cystic Ovary Syndrome
Status: COMPLETED
Conditions: Poly Cystic Ovary Syndrome
Interventions: DIETARY_SUPPLEMENT: Fenugreek seeds extract 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Administration of Oxygen to Cluster Headache Patients
Status: COMPLETED
Conditions: Cluster Headache Attacks
Interventions: DEVICE: Open Hudson Mask|DEVICE: Cluster headache mask with 3 L reservoir|DEVICE: Mask 3|DEVICE: Carnét oxygen demand valve|DEVICE: Carnét oxygen demand valve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Axillary Vein Access Versus Cephalic Venous Cutdown for Implantation of Cardiac Electronic Devices.
Status: COMPLETED
Conditions: Pacemaker|Implantable Cardioverter-defibrillator
Interventions: DEVICE: Ultrasound-guided axillary vein access|DEVICE: Cephalic vein access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Terlipressin Infusion During Whipple Procedure: Effect on Blood Loss and Transfusion Needs
Status: COMPLETED
Conditions: Terlipressin|Blood Loss
Interventions: DRUG: Terlipressin|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GTI-2040 and Capecitabine in Treating Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Male Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: BIOLOGICAL: GTI-2040|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Attempt to Reduce Community-Acquired Methicillin-Resistant Staphylococcus Aureus (MRSA) Infection in Soldiers
Status: COMPLETED
Conditions: Community-Acquired MRSA Infections|Abscesses|Cellulitis|Folliculitis
Interventions: DRUG: Mupirocin (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The Effect of a Meatless,Keto Restrictive Diet on Body Composition,Strength Capacity,Oxidative Stress,Immune Response
Status: COMPLETED
Conditions: Body Weight|Oxidative Stress|Trimethylamine N-oxide|Immunologic Factors|Glucose Metabolism Disorders|Insulin Resistance|Insulin Sensitivity|Insulin Tolerance|Carbohydrate Metabolism Disorder|Lipid Metabolism Disorders|Body Fat Disorder|Ketosis|Ketoses, Metabolic|Somatic Disorders
Interventions: OTHER: Meatless, restrictive ketogenic diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Aerobic Training and Combined in Inflammatory Markers in Patients With Adolescent Idiopathic Scoliosis
Status: COMPLETED
Conditions: Scoliosis|Adolescent Scoliosis
Interventions: OTHER: aerobic exercise|OTHER: combined exercise|DEVICE: treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cadonilimab Combined With Chemotherapy as First or Second Line Treatment in Recurrent or Metastatic Triple Negative Breast Cancer
Status: RECRUITING
Conditions: Triple-negative Breast Cancer|Cadonilimab
Interventions: DRUG: Cadonilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Impact of a Closed-loop Controlled Grasping Neuroprosthesis in Post-stroke Patients (PREHENSTROKE)
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Functional electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating a National Person-Centered Training Program to Strengthen the Dementia Care Workforce
Status: RECRUITING
Conditions: Aging|Knowledge, Attitudes, Practice|Long-Term Care|Dementia
Interventions: BEHAVIORAL: essentiALZ|BEHAVIORAL: Project ECHO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Cross-sectional, Observational Multicenter Study to Assess the Reasons for Choosing the 3-year Hormonal IUD and Level of IUDs Knowledge Among Women Aged 18 to 29 Years
Status: COMPLETED
Conditions: Intrauterine Devices, Medicated
Interventions: DRUG: Levonorgestrel (Jaydess, Skyla, BAY86-5028)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ventilation Tube Insertion for Unilateral Menière's Disease
Status: UNKNOWN
Conditions: Meniere Disease
Interventions: PROCEDURE: Transmyringeal ventilation tube insertion|PROCEDURE: Sham-treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Auditory Stimulation During Sleep on Brain Networks in Schizophrenia
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia
Interventions: OTHER: Closed loop auditory stimulation during sleep
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tipifarnib in Treating Patients With Relapsed or Refractory Lymphoma
Status: COMPLETED
Conditions: Anaplastic Large Cell Lymphoma|Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue|Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma|Nodal Marginal Zone Lymphoma|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult T-Cell Leukemia/Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Non-Hodgkin Lymphoma|Recurrent Small Lymphocytic Lymphoma|Splenic Marginal Zone Lymphoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Tipifarnib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tacrolimus During the Implantation and the Effect on Ischemia-reperfusion Injury in Liver Transplantation
Status: COMPLETED
Conditions: Ischemia Reperfusion Injury
Interventions: DRUG: Tacrolimus|OTHER: Saline solution 0.9% (250mL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-operative Nausea Vomiting in Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: ramosetron, ondansetron, dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GOLD Stage I Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Mild Chronic Obstructive Pulmonary Disease|Respiratory Symptoms|Physical Activity
Interventions: DRUG: Combination ipratropium/salbutamol or placebo (nebulization)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of a Combined Group-individual Schema Therapy for Borderline Personality Disorder
Status: COMPLETED
Conditions: Borderline Personality Disorder|Randomized Controlled Trial
Interventions: BEHAVIORAL: Group Schema therapy|BEHAVIORAL: Individual Schema therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Procalcitonin Guided Antibiotic Therapy
Status: WITHDRAWN
Conditions: Intra-Abdominal Infections
Interventions: OTHER: Procalcitonin-guided antibiotic treatment|OTHER: Standard of Care Antibiotic Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Renin-angiotensin-aldosterone System (RAAS) Blockade and Contrast Induced Nephropathy
Status: COMPLETED
Conditions: Radiographic Contrast Agent Nephropathy
Interventions: PROCEDURE: stop angiotensin converting enzyme inhibitor or angiotensin receptor blocker (ACE-I/ARB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Helping Children With Trauma
Status: TERMINATED
Conditions: Trauma|Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: Trauma Systems Therapy (TST)|BEHAVIORAL: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Carum Carvi on Thyroid Hormones and TSH Level
Status: UNKNOWN
Conditions: Thyroid Cancer Patients
Interventions: DRUG: Carum Cravi|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing Outpatient to Inpatient Cervical Ripening Using Dilapan-S®
Status: COMPLETED
Conditions: Labor, Induced|Cervix Uteri-Diseases
Interventions: DEVICE: Outpatient Dilapan-S|DEVICE: Inpatient Dilapan-S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Xeomin vs Botox for Treatment of Overactive Bladder Syndrome
Status: RECRUITING
Conditions: Overactive Bladder Syndrome
Interventions: DRUG: Xeomin 100 UNT Injection|DRUG: Botox 100 UNT Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pre-Exercise Nutrition Strategies on Body Temperature and Thermoregulatory Responses
Status: COMPLETED
Conditions: Impaired Thermoregulation
Interventions: OTHER: Carbohydrate Beverage|OTHER: Placebo Beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Standard- Versus Reduced-dose Tacrolimus Combined With Generic Mycophenolate Mofetil in De Novo Renal Transplantation
Status: COMPLETED
Conditions: Disorder Related to Renal Transplantation
Interventions: DRUG: Tacrolimus(reduced), Mycophenolate mofetil(standard)|DRUG: Tacrolimus(standard), Mycophenolate mofetil(reduced)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Asimadoline for the Treatment of Subjects With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Asimadoline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Diquafosol Tetrasodium Ophthalmic Solution, 2% Versus Placebo in Dry Eye Subjects (P08634)
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: diquafosol tetrasodium Ophthalmic Solution, 2%|DRUG: Non-preserved saline solution (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Transplantation of Cultured Fibroblast on Amniotic Membrane in Patients With Epidermolysis Bullosa
Status: COMPLETED
Conditions: Epidermolysis Bullosa With Mitten Hands
Interventions: BIOLOGICAL: Cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multilevel Intervention for Preventing Men's Use of Violence in Urban South Africa (Sonke CHANGE Trial)
Status: UNKNOWN
Conditions: Domestic Violence|Sexual Assault and Rape|Masculinity
Interventions: OTHER: Sonke CHANGE intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intracellular Counter-regulatory Mechanisms Following Low Blood Glucose
Status: COMPLETED
Conditions: Diabetes Mellitus Type I|Hypoglycemia
Interventions: DRUG: Insulin (Insuman Rapid)|DRUG: Glucose|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Brain Metastases Study: Radiotherapy Fractionation Schemes in the Treatment of Brain Metastases
Status: COMPLETED
Conditions: Neoplasm Metastasis|Brain Neoplasms
Interventions: PROCEDURE: Radiotherapy, dose fractionation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Pulmonary Ultrasound to Predict Evolution Towards Bronchopulmonary Dysplasia in Premature Infants at Gestational Age Less Than or Equal to 34 Weeks of Gestation
Status: UNKNOWN
Conditions: Bronchopulmonary Dysplasia
Interventions: OTHER: Pulmonary ultrasounds
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Different Endoscopic Gastric Cancer Risk Assessments
Status: RECRUITING
Conditions: Gastric Cancer Screening
Interventions: PROCEDURE: Kimura-Takemoto classification|PROCEDURE: EGGIM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Study of a Hand-held Device Plus Mobile App Versus Standard Eye Care Devices in Measuring Refractive Error of the Eye
Status: COMPLETED
Conditions: Refractive Errors|Astigmatism
Interventions: DEVICE: Hand-held device supported by a mobile application|DEVICE: Phoropter|DEVICE: Autorefractor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Oxytocin Dosage to Decrease Induction Duration
Status: COMPLETED
Conditions: Obesity|Labor, Induced|Oxytocin
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety/Efficacy Study: OPA-6566 Ophthalmic Solution in Subjects With Primary Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Primary Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: OPA-6566|DRUG: Placebo|DRUG: Latanoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Health Disparities During Pregnancy Through Vitamin D Supplementation
Status: COMPLETED
Conditions: Vitamin D3 Deficiency
Interventions: DRUG: Vitamin D3 4000 IU in gummy form|DRUG: Placebo gummy vitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intramedullary Bone Grafting for Open Tibial Shaft Fractures
Status: RECRUITING
Conditions: Tibial Fractures|Nonunion of Fracture|Delayed Union of Fracture
Interventions: PROCEDURE: Intramedullary Bone Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Oral Tramadol Versus Diclofenac For Pain Relief Before Outpatient Hysteroscopy:
Status: UNKNOWN
Conditions: Pain, Procedure
Interventions: DRUG: Tramadol|DRUG: Diclofenac|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effect of Preoperative Immunonutrition in Upper Digestive Tract
Status: UNKNOWN
Conditions: Immunonutrition|Gastric Cancer|Esophageal Cancer|Pancreas Cancer|Surgery--Complications
Interventions: DIETARY_SUPPLEMENT: Immunonutrition|DIETARY_SUPPLEMENT: Standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia
Status: RECRUITING
Conditions: Hypoxic-Ischemic Encephalopathy
Interventions: DRUG: RLS-0071|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab Combined With Apatinib and Oxaliplatin Plus S1 as Neoadjuvant Therapy for Borrmann IV、Large Borrmann III Type and Bulky N Positive Advanced Gastric Cancer
Status: RECRUITING
Conditions: Immunotherapy|Gastrict Cancer
Interventions: DRUG: Tislelizumab|DRUG: Apatinib Mesylate|DRUG: oxaliplatin|DRUG: Tegafur
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INNOVATION Study - Telmisartan (Micardis) in Incipient Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathies
Interventions: DRUG: Telmisartan capsule 40 mg|DRUG: Placebo|DRUG: Telmisartan capsule 80 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide After Allo-Hematopoietic Cell Transplant (HCT) in Acute Myelogenous Leukemia (AML) and Myelodysplastic Syndromes (MDS) Subjects With Minimal Residual Disease
Status: TERMINATED
Conditions: Leukemia, Myeloid|Myelodysplastic Syndromes
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Viral Infections and Airway Microbiome in Young Children With Cystic Fibrosis
Status: ENROLLING_BY_INVITATION
Conditions: Cystic Fibrosis in Children|Respiratory Bacterial Infection|Respiratory Viral Infection|Inflammation Lungs|Respiratory Morbidity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety and Efficacy of CCX168 in Subjects With ANCA-Associated Vasculitis
Status: COMPLETED
Conditions: Vasculitis
Interventions: DRUG: Placebo|DRUG: CCX168
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 124I-MIBG Tracer Evaluation of Myocardial Sympathetic Denervation and Assessment of Neuroendocrine Tumors.
Status: UNKNOWN
Conditions: Parkinson Disease|Neuroendocrine Tumors
Interventions: OTHER: MIBG label with I123 or I124|DEVICE: SPECT imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Periareolar Approach in Minimally Invasive Cardiac Surgery
Status: UNKNOWN
Conditions: Periareolar Minimally Invasive Cardiac Surgery
Interventions: PROCEDURE: Periareolar Approach in Minimally Invasive Cardiac Surgery (PAMI Technique)|PROCEDURE: inframammary approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Carboplatin Followed by Paclitaxel in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: gemcitabine hydrochloride|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Vitamin D Supplementation to Meticillin Resistant Staphylococcus Aureus (MRSA) Carriers
Status: COMPLETED
Conditions: Methicillin Resistant Staphylococcus Aureus|Vitamin D3 Deficiency
Interventions: DRUG: Cholecalciferol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Enamel Matrix Proteins on Clinical Attachment Level and Alveolar Bone in Periodontal Maintenance Patients
Status: COMPLETED
Conditions: Periodontal Bone Loss
Interventions: DRUG: Enamel Matrix Proteins Derivative|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Lumbar Interbody Fusion vs. Multidisciplinary Rehabilitation (LIFEHAB) Trial
Status: RECRUITING
Conditions: Chronic Low-back Pain
Interventions: PROCEDURE: Lumbar Interbody Fusion|BEHAVIORAL: Multidisciplinary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Inhaled Glutathione in Cystic Fibrosis Patients
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: reduced glutathione sodium salt|DRUG: 0.9% normal saline (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of Predictive Factors of Postoperative Pain After Oral Surgery From Phenotypic Parameters Easily Accessible Preoperatively (PHEDOPO)
Status: UNKNOWN
Conditions: Pain, Postoperative|Anxiety, Dental
Interventions: OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safety Study of DWP-450 (Botulinum Purified Neurotoxin, Type A) Injection to Treat Glabellar Lines
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: BIOLOGICAL: Botulinum purified neurotoxin, Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cediranib Maleate With or Without Dasatinib in Patients With HRPC-Resistant to Treatment With Docetaxel
Status: COMPLETED
Conditions: Hormone Refractory Prostate Cancer|Recurrent Prostate Cancer
Interventions: DRUG: cediranib maleate|DRUG: dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Physician Consideration of ePRO's, From Patients With Gout, Rheumatoid Arthritis, Sjogren's Syndrome or Systemic Lupus, on the Frequency of Therapeutic Adjustments
Status: RECRUITING
Conditions: Gout|Rheumatoid Arthritis|Sjogren's Syndrome|Systemic Lupus Erythematosus
Interventions: BEHAVIORAL: Therapeutic management following access by the physician to his patient's ePROs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Compare the Bioavailability of Two Tramadol Hydrochloride Tablet Products (50 mg and 200 mg, Respectively) at Steady-state Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy Subjects|Pharmacokinetics|Bioavailability
Interventions: DRUG: Tramadol HCl|DRUG: Tramadol HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Comorbid Spasticity and Urinary Incontinence in Residents of a Long-Term Care Facility
Status: COMPLETED
Conditions: Spasticity, Muscle|Muscular Diseases|Musculoskeletal Disease|Muscle Hypertonia|Muscle Spasticity|Neuromuscular Manifestations|Signs and Symptoms|Nervous System Diseases|Neurologic Manifestations
Interventions: DIAGNOSTIC_TEST: Neurological Examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Active Rehabilitation After Arthroscopic Rotator Cuff Repair
Status: COMPLETED
Conditions: Full Thickness Rotator Cuff Tear
Interventions: OTHER: early isometric loading after rotator cuff surgery|OTHER: passive motion after rotator cuff surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Comparison of Efficacy and Safety of Two Teriparatide Formulations: Osteofortil and Forteo
Status: UNKNOWN
Conditions: Postmenopausal Osteoporosis With Pathological Fracture
Interventions: DRUG: Teriparatide (rDNA origin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Calcium on Tasigna Pharmacokinetics (PK) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nilotinib Hydrochloride|DIETARY_SUPPLEMENT: calcium carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Neurohumoral Mechanism of Deferent Frequency Transcutaneous Electrical Acupoint Stimulation(TEAS)
Status: UNKNOWN
Conditions: Hypotension
Interventions: DEVICE: TEAS (transcutaneous electrical acupoint stimulation)|DEVICE: TEAS (transcutaneous electrical acupoint stimulation)|DEVICE: fake stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Fluorescent Tumor Marking Agent, Tozuleristide, for Imaging Oral Cavity Squamous Cell Cancer and High-Grade Oral Cavity Dysplasia During Surgery
Status: RECRUITING
Conditions: Oral Cavity Squamous Cell Carcinoma|Stage I Lip and Oral Cavity Cancer AJCC v8|Stage II Lip and Oral Cavity Cancer AJCC v8|Stage III Lip and Oral Cavity Cancer AJCC v8|Stage IVA Lip and Oral Cavity Cancer AJCC v8
Interventions: PROCEDURE: Near Infrared Imaging|PROCEDURE: Therapeutic Conventional Surgery|DRUG: Tozuleristide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lp-PLA2 and Coronary Atherosclerosis in Humans
Status: COMPLETED
Conditions: Coronary Atherosclerosis|Endothelial Dysfunction
Interventions: OTHER: Blood sampling from the Coronary Sinus and Aorta|PROCEDURE: Intravascular Ultrasound of the coronary artery.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Study on Mesenchymal Stem Cells Used in the Reconstruction Surgery of the Supraspinatus Muscle Lesions
Status: UNKNOWN
Conditions: Rotator Cuff Tear
Interventions: BIOLOGICAL: mesenchymal stem cells|PROCEDURE: without mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Effects of Endobronchial Valve Implantation on Cardiac Function and Skeletal Muscle Function
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: PROCEDURE: Lung volume reduction surgery with endobronchial valve implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Study Neladenoson Bialanate Over 20 Weeks in Patients With Chronic Heart Failure With Reduced Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Neladenoson bialanate (BAY1067197)|DRUG: Neladenoson bialanate (BAY1067197)|DRUG: Neladenoson bialanate (BAY1067197)|DRUG: Neladenoson bialanate (BAY1067197)|DRUG: Neladenoson bialanate (BAY1067197)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sarcopenia And Balance In Postmenopausal Osteoporosis
Status: UNKNOWN
Conditions: Osteoporosis, Postmenopausal|Balance; Distorted|Sarcopenia
Interventions: DIAGNOSTIC_TEST: Berg Balance Scale|DIAGNOSTIC_TEST: Timed Up and Go Test|DIAGNOSTIC_TEST: Jamar hand dynamometer|DIAGNOSTIC_TEST: Calf circumference
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of the Pathogenesis and Molecular Mechanism of "YURE" in Internal Intractable Diseases
Status: UNKNOWN
Conditions: Stroke
Interventions: DRUG: Chinese herbs formula|DRUG: Mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Pharmacodynamic Properties of NN1218 in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: Faster-acting insulin aspart|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Effects of Prunus Cerasus and Apocynum Venetum On Sleep and Anxiety in Adults With Insomnia
Status: COMPLETED
Conditions: Insomnia
Interventions: OTHER: Sip2Sleep: Montmorency Cherry and Apocynum Venetum
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Harvesting Health Program in Improving Diet and Physical Activity Level in Cancer Survivors
Status: COMPLETED
Conditions: Cancer Survivor
Interventions: OTHER: education|OTHER: nutrition intervention|BEHAVIORAL: exercise intervention|OTHER: questionnaire administration|OTHER: laboratory biomarker analysis|OTHER: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SHR1459 in Combination With YY-20394 in Recurrent and Refractory B-cell Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Recurrent and Refractory B-cell Non-Hodgkin's Lymphoma
Interventions: DRUG: SHR1459 ；YY-20394|DRUG: SHR1459 ；YY-20394|DRUG: Gemcitabine-Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Medical Treatment and Prognosis of Postural Orthostatic Tachycardia Syndrome (POTS)
Status: COMPLETED
Conditions: Postural Orthostatic Tachycardia Syndrome
Interventions: DRUG: Propranolol|DRUG: Bisoprolol|DRUG: Propranolol+pyridostigmine|DRUG: Bisoprolol+pyridostgmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood-pressure Measuring in Patients Carrying a Left Ventricular Assist Device
Status: COMPLETED
Conditions: Left Ventricular Assist Device
Interventions: DEVICE: Blood-pressure measuring (Nellcor™ Adult SpO2 Sensor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Rivaroxaban and Apixaban in Comparison to Warfarin in Left Ventricular Clot- Clinical Trial
Status: RECRUITING
Conditions: Left Ventricular Thrombus
Interventions: DRUG: Warfarin|DRUG: Rivaroxaban 20 MG Oral Tablet|DRUG: Apixaban 5mg or 2.5mg oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of a Self-Guided Mindfulness Mobile Application to Improve Pain Outcomes in Individuals With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteo Arthritis Knee|Pain
Interventions: DEVICE: Intervention -- "Headspace" mindfulness application|DEVICE: Control -- "My Water Balance" application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Shared Decision Making for Prostate Cancer Screening: a Practice-Based Randomized Controlled Trial
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: OTHER: You Decide|OTHER: Reducing Your Risks in the Crash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Stool DNA-based SDC2 Methylation Test for the Early Detection of Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer|Advanced Colorectal Neoplasm|Advanced Adenomas|Non-neoplastic Polyps|Non-advanced Adenomas
Interventions: DEVICE: EarlyTect® CRC test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fasting Comparative Bioavailability Study of 2 Meloxicam 15 mg Tablets in Healthy Volunteers Under Fasting Condition
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Reumoxicam® 15 mg tablets (PJSC "Farmak", Ukraine)|DRUG: Movalis 15 mg tablets ("Boehringer Ingelheim Ellas A.E.", Greece)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Assessment of a New Closed-loop Algorithm in Type 1 Diabetes (Saddle Point Model Predictive Control : SP-MPC) (PPA)
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: OTHER: open-loop night|OTHER: closed-loop night
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Protein Supplemented Very Low Calorie Meals on Weight Loss
Status: UNKNOWN
Conditions: Obesity|Sarcopenic Obesity
Interventions: OTHER: Protein supplemented very low calorie diet program|OTHER: Conventional low calorie diet program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imagery Enhanced Cognitive Bias Modification for Chronic Worry
Status: SUSPENDED
Conditions: Excessive Worry
Interventions: BEHAVIORAL: Standard cognitive bias modification|BEHAVIORAL: Imagery enhanced cognitive bias modification|BEHAVIORAL: Neutral Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Xiyanping Injection for the Treatment of New Coronavirus Infected Pneumonia
Status: UNKNOWN
Conditions: 2019 Novel Coronavirus Pneumonia
Interventions: DRUG: Xiyanping injection|DRUG: Lopinavir / ritonavir, alpha-interferon nebulization,Abidor Hydrochloride
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lopinavir/ Ritonavir, Ribavirin and IFN-beta Combination for nCoV Treatment
Status: COMPLETED
Conditions: Novel Coronavirus Infection
Interventions: DRUG: Lopinavir/ritonavir|DRUG: Ribavirin|DRUG: Interferon Beta-1B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT