pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Impact of Subgingival Instrumentation on Psychological Distress and Mental Health Status in Bruxers With Periodontitis
Status: RECRUITING
Conditions: Periodontal Diseases|Bruxism|Periodontitis|Distress, Emotional
Interventions: OTHER: Subgingival instrumentation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Comparative Study(Open-Label) of MRA for Rheumatoid Arthritis(RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: MRA (Tocilizumab)|OTHER: current treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Chemotherapy and Systemic Chemotherapy Versus Systemic Chemotherapy After Curative Resection of Serosa-positive Gastric Cancer
Status: UNKNOWN
Conditions: Advanced Gastric Cancer With Serosal Invasion
Interventions: PROCEDURE: surgery|DRUG: adjuvant systemic chemotherapy|DRUG: Early postoperative intraperitoneal chemothgerapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QUALITE Study - A Study of Fuzeon (Enfuvirtide) in Treatment-Experienced Patients With Human Immunodeficiency Virus-1 (HIV-1) Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: ARV regimen|DRUG: enfuvirtide [Fuzeon]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motivational Interviewing to Support LDL-C Therapeutic Goals and Lipid-Lowering Therapy Compliance in Patients With Acute Coronary Syndromes: a Prospective Randomized Clinical Study
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: BEHAVIORAL: Motivational Interview
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Systemic Chemotherapy, Lenvatinib Plus Sintilimab for ICC With Distant Metastasis
Status: UNKNOWN
Conditions: ICC
Interventions: DRUG: Systemic Chemotherapy|DRUG: Lenvatinib|DRUG: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Bioavailability of XS004 (Dasatinib) Formulation G and SPRYCEL® (Dasatinib) in Healthy, Adult Subjects Under Fasting Conditions
Status: COMPLETED
Conditions: Biological Availability
Interventions: DRUG: Dasatinib ASD 100 mg|DRUG: Dasatinib 140 MG [Sprycel]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Supporting Elderly People With Cognitive Impairment During and After Hospital Stays- Intersectoral Care Management
Status: COMPLETED
Conditions: Dementia|Cognitive Impairment|Neurodegenerative Diseases
Interventions: BEHAVIORAL: Dementia Care Management (DCM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bacteriophage Therapy TP-102 in Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer|Pseudomonas Aeruginosa Infection|Staphylococcus Aureus Infection|Acinetobacter Infection
Interventions: BIOLOGICAL: TP-102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mode of Drainage Of Bilaterally Obstructed Kidneys
Status: UNKNOWN
Conditions: Obstructive Nephropathy
Interventions: PROCEDURE: unilateral drainage of Bilaterally Obstructed Kidneys|PROCEDURE: bilateral drainage of Bilaterally Obstructed Kidneys
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Radiation Therapy in Treating Patients With Newly Diagnosed Brain Metastases From Kidney Cancer, Melanoma, or Sarcoma
Status: COMPLETED
Conditions: Kidney Cancer|Melanoma (Skin)|Metastatic Cancer|Ovarian Cancer|Sarcoma
Interventions: RADIATION: stereotactic radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Trial of MitoQ for Raised Liver Enzymes Due to Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Mitoquinone mesylate (MitoQ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Nightmares in Posttraumatic Stress Disorder With Dronabinol
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: BX-1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suprachoroidal Injection of Triamcinolone Acetonide in Resistant Diabetic Macular Edema, CRVO, Pseudophakic Cystoid Macular Edema and Diabetic Macular Edema Following Pars Plana Vitrectomy
Status: NOT_YET_RECRUITING
Conditions: Retinal Edema
Interventions: DRUG: Triamcinolone Acetonide 40Mg/Ml Inj,Susp_#1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Precision Treatment of Recurrent/Metastatic Salivary Gland Carcinoma Guided by Molecular Typing
Status: RECRUITING
Conditions: Locally Advanced or Recurrent/Metastatic Salivary Gland Carcinoma|Neoadjuvant or Conversion Therapy|Precision Therapy
Interventions: DRUG: Vedolizumab|DRUG: larotinib or enttraitinib|DRUG: antiandrogen drug treatment|DRUG: ESG401|DRUG: small molecule multi-target tyrosine kinase inhibitors± Chemioterapy|DRUG: albumin paclitaxel with platinum
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Safety and Immune Response to the HIV-1 CH505 Transmitted/Founder gp120 Adjuvanted With GLA-SE in Healthy, HIV-exposed Uninfected Infants
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: CH505TF gp120|BIOLOGICAL: GLA-SE adjuvant|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of a Transdiagnostic, Emotion-focused Group Intervention for Young Adults With Substance Use Disorders
Status: COMPLETED
Conditions: Substance Use Disorders|Depression|Anxiety|Emotional Disorder|Suicidal Ideation|Suicidal and Self-injurious Behavior
Interventions: BEHAVIORAL: Unified Protocol (UP)|OTHER: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Mets - Capecitabine Plus Sunitinib and WBRT
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: sunitinib|DRUG: capecitabine|RADIATION: WBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Refining MDR-TB Treatment (T) Regimens (R) for Ultra(U) Short(S) Therapy(T)-PLUS
Status: ACTIVE_NOT_RECRUITING
Conditions: Multidrug Resistant Tuberculosis
Interventions: DRUG: Bedaquiline|DRUG: Pyrazinamide|DRUG: Linezolid|DRUG: Cycloserine|DRUG: Clofazimine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of FLACS USFREE Compared to Traditional Surgery Using Ultrasound.
Status: COMPLETED
Conditions: Senile Cataract|Cataract
Interventions: OTHER: FLACS USFREE|OTHER: Traditional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 24-week Arterial Stiffness Study With Fluticasone Furoate/Vilanterol in COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Fluticasone Furoate/Vilanterol|DRUG: Vilanterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Adenovirus Vector Engineered to Express hIL-12 in Combination With Activator Ligand to Treat Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: INXN-2001|DRUG: INXN-1001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plastibell Versus Conventional Dissection Techniques for Circumcision in Infants and Children
Status: UNKNOWN
Conditions: Circumcision, Male
Interventions: DEVICE: Plastibell|PROCEDURE: conventional sleeve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Active Surveillance for Low-risk Prostate Cancer - Evaluation of the Efficacy of Minimally Invasive Active Surveillance
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: MRI+targeted biopsies+Stockholm3-test|DIAGNOSTIC_TEST: PSA + systematic biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetics Study of MCI-186 in Subjects With Mild or Moderate Renal Impairment
Status: COMPLETED
Conditions: Renal Impairment|Healthy
Interventions: DRUG: MCI-186
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Trial Comparing Efficacy, Tolerability, and Safety of GZR101 Injection Once Daily (OD) and GZR33-70 Injection OD
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: GZR101 Injection|DRUG: GZR33 Injection|DRUG: Insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression
Status: NOT_YET_RECRUITING
Conditions: Suicide|Depressive Disorder, Treatment-Resistant|Ketamine|Molecular Mechanisms of Pharmacological Action|Neurotransmitter Agents|Excitatory Amino Acid Agents|Physiological Effects of Drugs|Depressive Disorder, Major|Depressive Disorder|Depression|Mental Disorders|Mood Disorders|Behavioral Symptoms
Interventions: DRUG: (2R,6R)-hydroxynorketamine (0.25 to 2.0 mg/kg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Electronic Cigarettes as a Harm Reduction Strategy Among People Living With HIV/AIDS
Status: ACTIVE_NOT_RECRUITING
Conditions: Nicotine Addiction
Interventions: OTHER: Nicotine patch and gum|BEHAVIORAL: Minnesota Nicotine Withdrawal Scale (MNWS)|BEHAVIORAL: ASSIST (the Alcohol, Smoking and Substance Involvement Screening)|BEHAVIORAL: Counseling|OTHER: NIDA Standardized Research E-cigarettes (SREC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Monitoring in Cancer Care: A Platform Study
Status: RECRUITING
Conditions: Head and Neck Carcinoma|Hematopoietic and Lymphoid Cell Neoplasm|Lung Carcinoma|Malignant Digestive System Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Computer-Assisted Intervention|PROCEDURE: Patient Monitoring|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mother's Recorded Voice Versus Dexmedetomidine on Postoperative Agitation
Status: COMPLETED
Conditions: Agitation, Emergence
Interventions: BEHAVIORAL: the mother's recorded voice|DRUG: Dexmedetomidine|OTHER: saline 0.9% placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Optimal Timing of Cord Clamping in Preterm Pregnancy Following Vaginal or Cesarean Delivery
Status: COMPLETED
Conditions: Preterm Birth
Interventions: OTHER: Clamp cord 20, 40 or 60 seconds following vaginal or cesarean delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neostigmine Reversal And Neuromuscular Recovery
Status: COMPLETED
Conditions: Residual Neuromuscular Block
Interventions: DRUG: Neostigmine Group|OTHER: No Neostigmine group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Non Absorbable Mesh Reinforcement of Midline Incision Closure in High Risk Patients, Onlay Versus Preperitoneal Position, a Comparative Clinical Trial
Status: COMPLETED
Conditions: Midline Incisions|High Risk Patients|Mesh Reinforcement|Incisional Hernia
Interventions: PROCEDURE: midline mesh reinforcement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Supraclavicular Versus Combined Block for Ulnar and Median Distribution Hand Surgery
Status: WITHDRAWN
Conditions: Hand Surgery (Ulnar or Median Distribution)|Peripheral Nerve Block
Interventions: PROCEDURE: Combined nerve block|PROCEDURE: Supraclavicular block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Selective Bilateral Laryngeal Reinnervation as a Secondary Treatment in Case of Bilateral Vocal Fold Paralysis
Status: UNKNOWN
Conditions: Bilateral Vocal Fold Paralysis
Interventions: PROCEDURE: Surgery for bilateral laryngeal reinnervation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Supplement for Joint: the OLE Study
Status: COMPLETED
Conditions: Knee Discomfort|Knee Pain
Interventions: DIETARY_SUPPLEMENT: Bonolive|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Sublingual Versus Oral Misoprostol Administration Following Mifepristone 200 mg for Abortion up to 63 Days Gestation
Status: COMPLETED
Conditions: Induced Abortion
Interventions: DRUG: Mifepristone, misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Culture-guided Antimicrobial Prophylaxis in Men Undergoing Prostate Biopsy.
Status: COMPLETED
Conditions: Complication|Infection|Prostate Cancer
Interventions: DRUG: Ciprofloxacin|DRUG: Trimethoprim/Sulfamethoxazole|DRUG: Fosfomycin|DRUG: Pivmecillinam/augmentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Relevance of T Lymphocytes Tumor Infiltrates CD8 and Foxp3 as Immune Prognostic Biomarker in Breast Cancer Treated by Neo Adjuvant Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: immunohistochemical detection of lymphocytes T CD8+/Foxp3 ratio
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Aquatic Exercise Versus Aerobic Exercise on Primary Dysmenorrhea and Quality of Life in Adolescent Females
Status: COMPLETED
Conditions: Dysmenorrhea Primary
Interventions: OTHER: Aquatic Exercise|OTHER: Aerobic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ATERO : A Randomised Study With Tranexamic Acid in Epistaxis of Rendu Osler Syndrome
Status: COMPLETED
Conditions: Telangiectasia, Hereditary Hemorrhagic|Osler-Rendu Disease
Interventions: DRUG: tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid to Improve Arthroscopic Visualization in Shoulder Surgery
Status: COMPLETED
Conditions: Rotator Cuff Injuries|Rotator Cuff Tears|Subacromial Impingement|Subacromial Impingement Syndrome
Interventions: DRUG: Epinephrine|DRUG: Tranexamic acid|DRUG: Epinephrine and Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 2/2 D-Cycloserine Augmentation of CBT for Pediatric OCD
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: D-Cycloserine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vinflunine in Patients With Locally Advanced or Metastatic Transitional Cell Carcinoma of the Urothelium
Status: COMPLETED
Conditions: Transitional Cell Carcinoma|Bladder Neoplasms|Kidney Neoplasms|Ureter Neoplasms|Bladder Cancer|Neoplasm, Bladder
Interventions: DRUG: vinflunine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Adjuvant Ipilimumab and Nivolumab in Subjects With High-risk Ocular Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma|Ocular Melanoma
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sintilimab Plus FOLFIRI as Salvage Therapy for Patients With Advanced Gastric Cancer
Status: RECRUITING
Conditions: Unresectable/Metastatic Gastric Cancer
Interventions: DRUG: Sintilimab+irinotecan+leucovorin folinate+fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S9902 Docetaxel Plus Carboplatin in Treating Patients With Metastatic or Recurrent Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: carboplatin|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CREATE-1: A Study to Assess the Efficacy and Safety of AXS-02 in Patients With CRPS-1
Status: UNKNOWN
Conditions: Complex Regional Pain Syndrome|Reflex Sympathetic Dystrophy
Interventions: DRUG: AXS-02 (oral zoledronate)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemo-proton Radiotherapy With or Without Resection and Spacer Insertion for Loco-regional Recurrence of Previous Irradiated Rectal Cancer
Status: UNKNOWN
Conditions: Previously Irradiated Recurrent Rectal Cancer
Interventions: RADIATION: Concurrent chemo-proton therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Acetilcysteine in 'Rescue' Therapy for Helicobacter Pylori Infection. Pilot Study
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Group A: NCA 600 mg+antibiotics|DRUG: Group B: antibiotic treatment (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Mindfulness Training Following Early Life Adversity
Status: COMPLETED
Conditions: Stress|Mindfulness|Early Life Adversity
Interventions: BEHAVIORAL: Mindfulness|BEHAVIORAL: Coping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study of the CardiAQ™ TMVI System (Transapical DS)
Status: TERMINATED
Conditions: Mitral Insufficiency|Heart Valve Disease|Cardiovascular Disease|Heart Disease
Interventions: DEVICE: CardiAQ TMVI System (Transapical DS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Increased Fruit and Vegetable Intake on Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: 5 portions fruit and vegetables/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Comparison of Two Daily Disposable Soft Contact Lenses
Status: COMPLETED
Conditions: Myopia|Refractive Errors
Interventions: DEVICE: verofilcon A contact lenses|DEVICE: somofilcon A contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High-flow Nasal Oxygen During Rigid Bronchoscopy Under General Anesthesia: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Foreign Bodies|Tumor|Stenosis Trachea|Bronchus Tumour
Interventions: DEVICE: Optiflow ™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Impact of a Telephone Reminiscence Program
Status: RECRUITING
Conditions: Mental Health|Loneliness|Social Isolation
Interventions: BEHAVIORAL: Telephone Reminiscence Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trial Looking at the Comparability of 2 Different Forms of Semaglutide
Status: COMPLETED
Conditions: Healthy Volunteers (Diabetes Mellitus, Type 2)
Interventions: DRUG: Semaglutide B, 1.34 mg/mL|DRUG: Semaglutide D, 1.0 mg/mL|DRUG: Semaglutide D, 1.0 mg/mL|DRUG: Semaglutide B, 1.34 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics of Margetuximab in Chinese Patients With HER2+ MBC
Status: COMPLETED
Conditions: HER2 Positive Metastatic Breast Cancer
Interventions: DRUG: Margetuximab Margetuximab-IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectivenness and Implementation of an Intervention to Improve Primary Care Patient Safety
Status: NOT_YET_RECRUITING
Conditions: Patient Safety
Interventions: BEHAVIORAL: SinergiAPS intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: OCT in Rare Chorioretinal Diseases
Status: RECRUITING
Conditions: Retinal Artery Occlusions|Polypoidal Choroidal Vasculopathy|Retinal Arterial Macroaneurysm|Juxtafoveal Telangiecasia|Central Serous Chorioretinopathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intracavitary Injection of hUMSCs in Acute Basal Ganglia Hematoma After Stereotactic Aspiration
Status: UNKNOWN
Conditions: Basal Ganglia Hematoma
Interventions: PROCEDURE: stereotactic surgery|BIOLOGICAL: hUMSCs|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Technique of Skin Stretching for Acute Burn Treatment and Scar Reconstruction
Status: COMPLETED
Conditions: Burns|Scars
Interventions: PROCEDURE: Split skin graft|PROCEDURE: skin stretching device|PROCEDURE: serial excision|PROCEDURE: skin stretching device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bleeding-Model Clinical Study
Status: COMPLETED
Conditions: Gingivitis
Interventions: DRUG: 0.454% stannous fluoride|DRUG: 0.76% sodium monofluorophosphate|DRUG: 0.454% stannous fluoride AM and 0.76% sodium monofluorophosphate PM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Psychotherapy and Case Management for Karen Refugees in Primary Care
Status: UNKNOWN
Conditions: Delivery of Intensive Behavioral Services to Refugees in Primary Care
Interventions: BEHAVIORAL: Intensive Psychotherapy and case management for refugee trauma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prediction for Coma Recovery With Comaweb
Status: UNKNOWN
Conditions: Brain Injury, Coma|Cardiac Arrest (CA)|Traumatic Brain Injury (TBI)|Aneurysmal Subarachnoid Hemorrhages (aSAH)
Interventions: OTHER: MRI sequence|OTHER: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Immune Memory Foll Pry Vaccination With DTPw-HBV/Hib Vaccine Formulation; Immuno & Reacto of Booster Dose at 15-18 Mths
Status: COMPLETED
Conditions: Hib Disease|Hepatitis B|Pertussis|Prophylaxis of Diphtheria|Tetanus
Interventions: BIOLOGICAL: Diphteria, tetanus, whole-cell pertussis, hepatitis B & Hib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of Minocycline for Reducing Symptom Burden in Colorectal Patients
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Minocycline|DRUG: Placebo|BEHAVIORAL: Questionnaires|BEHAVIORAL: Sensory Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immune Modulation by Enhanced vs Standard Prehabilitation Program Before Major Surgery
Status: COMPLETED
Conditions: Surgery|Immune System and Related Disorders|Preoperative Care|Gastrointestinal Disease|Urological Disease|Gynecologic Disease|Thoracic Diseases
Interventions: BEHAVIORAL: Physical Prehabilitation|BEHAVIORAL: Stress Reduction Prehabilitation|BEHAVIORAL: Cognitive Prehabilitation|BEHAVIORAL: Nutrition Prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Permanent Celiac Plexus Block: Comparison of Pain Score in Unilateral and Bilateral Posterior Percutaneous Approach
Status: COMPLETED
Conditions: Abdominal Cancer|Cancer Pain|Cancer of Pancreas
Interventions: DRUG: Unilateral Neurolytic Celiac Plexus Block with Absolute Alcohol|DRUG: Bilateral Neurolytic Celiac Plexus Block with Absolute Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving How People Living With Dementia Are Selected for Care Coordination
Status: COMPLETED
Conditions: Dementia
Interventions: BEHAVIORAL: Care coordination delivered based on perceived need|BEHAVIORAL: Care coordination delivered based on usual care (e.g. discharge from hospital)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: "Effect of Sonic Activation Assisted Irrigation and Apical Enlargement on Postoperative Endodontic Pain"
Status: UNKNOWN
Conditions: Postoperative Pain|Endodontically Treated Teeth
Interventions: PROCEDURE: Apical enlargement|PROCEDURE: Apical enlargement + Sonic Activation Assisted Irrigation|PROCEDURE: Non Apical enlargement|PROCEDURE: Non Apical enlargement + Sonic Activation Assisted Irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EEG Synchronized TMS Trial for Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy/Safety Study of Brisdelle™ (Formerly Known as Mesafem) in the Treatment of Vasomotor Symptoms (VMS)
Status: COMPLETED
Conditions: Postmenopausal Symptoms
Interventions: DRUG: Brisdelle (paroxetine mesylate)|DRUG: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Computer-Facilitated 5A's for Smoking Cessation in Primary Care
Status: COMPLETED
Conditions: Nicotine Addiction|Smoking Cessation
Interventions: OTHER: Computer Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Masitinib in Severe Indolent or Smoldering Systemic Mastocytosis Unresponsive to Optimal Symptomatic Treatment
Status: RECRUITING
Conditions: Indolent Systemic Mastocytosis
Interventions: DRUG: Masitinib|OTHER: Placebo|OTHER: Best Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Tredaptive on Serum Lipoproteins and Inflammatory Markers
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: nicotinic acid/laropiprant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study Investigating Safety, Tolerability and Pharmacokinetics of Ascending Doses of Lu AE04621 in Parkinson Disease Patients
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: 0.04 mg Lu AE04621|DRUG: 0.08 mg Lu AE04621|DRUG: 0.2 mg Lu AE04621|DRUG: 0.4 mg Lu AE04621|DRUG: 0.6 mg Lu AE04621|DRUG: 0.8 mg Lu AE04621|DRUG: 1.0 mg Lu AE04621|DRUG: 1.2 mg Lu AE04621
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Healthy Males to Assess the Bioavailability of 4 Different Fostamatinib Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fostamatinib|DRUG: Fostamatinib|DRUG: Fostamatinib|DRUG: Fostamatinib|DRUG: Fostamatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Failed on One Prior Anti-TNF Therapy (RESET)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The PreQ-20 TRIAL, a Prospective Cohort Study of Patients Undergoing Prepectoral Breast Reconstruction
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Quality of Life|Surgery--Complications
Interventions: PROCEDURE: Prepectoral reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Glucose Clamp Study of Wockhardt's Insulin Human Regular for Injection and Actrapid, in Healthy Subjects.
Status: COMPLETED
Conditions: Diabetes
Interventions: BIOLOGICAL: Wosulin R|BIOLOGICAL: Actrapid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Tapentadol Immediate-Release in the Treatment of Patients With Acute Pain From Bunionectomy
Status: COMPLETED
Conditions: Hallux Valgus
Interventions: DRUG: Tapentadol IR 50 mg|DRUG: Tapentadol IR 75 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Examining Tolerance to CNS Stimulants in ADHD
Status: COMPLETED
Conditions: Attention-deficit/Hyperactivity Disorder
Interventions: DRUG: Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FLUAD® vs. Fluzone® High-Dose Study
Status: COMPLETED
Conditions: Pain|Quality of Life|Injection Site Reaction|Side Effect of Drug|Adverse Drug Event
Interventions: BIOLOGICAL: FLUAD®|BIOLOGICAL: Fluzone® High-Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pembrolizumab With Talimogene Laherparepvec or Placebo in Unresected Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: Talimogene Laherparepvec|DRUG: Pembrolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase1 of Neratinib+Trastuzumab, Pertuzumab, Paclitaxel in Patients With Advanced Solid Tumors/HER2+
Status: TERMINATED
Conditions: Solid Tumor
Interventions: DRUG: Neratinib|DRUG: Paclitaxel|DRUG: Pertuzumab|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Duloxetine Compassionate Use in Patients Who Have Completed a Previous Neuroscience Duloxetine Clinical Trial
Status: NO_LONGER_AVAILABLE
Conditions: Major Depressive Disorder|Fibromyalgia|Diabetic Peripheral Neuropathic Pain|Generalized Anxiety Disorder
Interventions: DRUG: Duloxetine Hydrochloride
Study Type: EXPANDED_ACCESS
Clinical trial: Effects of Low and Moderate Fat Diets on Lipids, Inflammation and Vascular Reactivity in the Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome X|Dyslipidemias
Interventions: BEHAVIORAL: Moderate Fat and Moderate Carbohydrate Diet|BEHAVIORAL: Low Fat and High Carbohydrate Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Seroprevalence of SARS-Cov-2 Antibodies in Children
Status: COMPLETED
Conditions: COVID|Corona Virus Infection|Multisystem Inflammatory Syndrome in Children
Interventions: DIAGNOSTIC_TEST: Covid-19 Antibody testing (IgG and IgM)|OTHER: Blood Storage
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of AGN-210669 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patients With Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: AGN-210669|DRUG: bimatoprost|DRUG: bimatoprost vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of rhPTH(1-84) in Japanese Healthy Subjects Compared With Matched Caucasian Healthy Adult Subjects
Status: COMPLETED
Conditions: Hypoparathyroidism
Interventions: DRUG: rhPTH(1-84)|DRUG: rhPTH(1-84)|DRUG: rhPTH(1-84)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estradiol vs Lysteda in Treatment of Heavy Menstrual Bleeding
Status: UNKNOWN
Conditions: Menstrual Cycle and Uterine Bleeding Disorders
Interventions: DRUG: Estradiol|DRUG: Lysteda
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CD-NP in Subjects With Stable Chronic Heart Failure
Status: COMPLETED
Conditions: Stable Chronic Heart Failure
Interventions: DRUG: CD-NP|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stem Cells for the Treatment of Pouchitis
Status: WITHDRAWN
Conditions: Pouchitis|Crohn's Disease|Ulcerative Colitis Chronic|Inflammatory Bowel Diseases|Pouch, Ileal
Interventions: DRUG: Mesenchymal Stem Cells (MSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Menstrual Blood Stem Cells in Poor Ovarian Responders
Status: COMPLETED
Conditions: Poor Ovarian Response|Infertility, Female
Interventions: BIOLOGICAL: Autologous Menstrual Blood Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Daunorubicin and Cytarabine With or Without Uproleselan in Treating Older Adult Patients With Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy
Status: SUSPENDED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|DRUG: Daunorubicin|DRUG: Uproleselan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SCT200 Injection in Patients With Head and Neck Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Anti-EGFR monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Robotic Glove Hand Training in Patients After Median Nerve Transfer
Status: RECRUITING
Conditions: Median Nerve Injury
Interventions: OTHER: Robot Glove Hand Training|OTHER: Conventional Hand Rehabilitation Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Weight Gain and Dyslipidemia by Green Tea in Patients Initiating Therapy With Olanzapine
Status: WITHDRAWN
Conditions: Bipolar Disorder|Schizophrenia
Interventions: DIETARY_SUPPLEMENT: Green Tea|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Anxiety Disorder|Cognitive/Functional Effects|Colorectal Cancer|Depression|Fatigue|Psychosocial Effects of Cancer and Its Treatment|Sleep Disorders|Excercise
Interventions: BEHAVIORAL: exercise intervention|OTHER: counseling intervention|OTHER: educational intervention|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration|OTHER: study of socioeconomic and demographic variables|PROCEDURE: fatigue assessment and management|PROCEDURE: quality-of-life assessment|OTHER: Educational Intervention|OTHER: Fitness testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Role of Vitamin D in the Prevention and Treatment of Diseases Associated With Insulin Resistance
Status: COMPLETED
Conditions: Vitamin D-deficient|Insulin-resistant
Interventions: DIETARY_SUPPLEMENT: Vitamin D|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Hypofraction Radiotherapy for Limited-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Safety Issues|Efficacy, Self
Interventions: RADIATION: High-dose hypofraction Arm|RADIATION: Low-dose hypofraction Arm (Standard BED)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Single Dose Study Of PF-04360365 In Japanese Patients With Mild To Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: PF-04360365|BIOLOGICAL: PF-04360365|BIOLOGICAL: PF-04360365|BIOLOGICAL: PF-04360365|DRUG: Placebo|BIOLOGICAL: PF-04360365
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Comparison of Different Flowable Resin Composites
Status: ACTIVE_NOT_RECRUITING
Conditions: Tooth Diseases
Interventions: DEVICE: Constic|DEVICE: G-ænial Universal Flo|DEVICE: Tetric N-Flow (self-etch)|DEVICE: Tetric N-Flow (etch&rinse)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of IV Versus PO Acetaminophen Postoperatively for Opioid Consumption After Cesarean Section
Status: UNKNOWN
Conditions: Postoperative Pain|Cesarean Section|Acetaminophen
Interventions: DRUG: Acetaminophen|DRUG: Acetaminophen|DRUG: Placebos|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of Visual Dependence in PPPD Patients With the Aid of Virtual Reality.
Status: RECRUITING
Conditions: PPPD
Interventions: DEVICE: Optokinetic stimulation through Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Perfusion Imaging Evaluation for Ischemic Stroke on 6-24 Hours Undergoing Endovascular Thrombectomy
Status: RECRUITING
Conditions: Stroke, Acute Cerebral Infarction
Interventions: PROCEDURE: Endovascular Thrombectomy|PROCEDURE: Endovascular Thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Two Arthroscopic Rotator Cuff Repair Techniques: Knot-tying Versus Knotless Suture-bridge Technique
Status: COMPLETED
Conditions: Rotator Cuff Tears|Rotator Cuff Injuries
Interventions: PROCEDURE: Arthroscopic rotator cuff repair with knotless suture-bridge technique|PROCEDURE: Arthroscopic rotator cuff repair with knot-tying suture-bridge technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tai-Chi and Aerobic Exercise to Improve Emotional Symptom Cluster in Late-stage Lung Cancer Patients
Status: RECRUITING
Conditions: Advanced Lung Non-Small Cell Carcinoma
Interventions: BEHAVIORAL: Tai-Chi intervention|BEHAVIORAL: Aerobic exercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Postprandial Lipid Metabolism in Patients With Hypertriglyceridemia and Normo-lipidemic Controls: Medium Chain Fatty Acids (MCT) in Comparison to Long-chain, Saturated Fatty Acids (SFA) and Mono-unsaturated Fatty Acids (MUFA)
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: OTHER: MCT|OTHER: SFA|OTHER: MUFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: MRI Review of ACLR With and Without Lateral Extra-articular Tenodesis
Status: WITHDRAWN
Conditions: Ruptured Achilles Tendon
Interventions: DIAGNOSTIC_TEST: Anterior cruciate ligament Reconstruction (ACLR)|DIAGNOSTIC_TEST: ACLR with lateral extra-articular tenodesis (LET)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Single Intra-articular Injection of aMAT vs PRP in Patients With OA of the Knee
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: injection of autologous micro-fragmented adipose tissue (aMAT)|BIOLOGICAL: injection of Platelet-rich Plasma (PRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EFFECT OF SCALING ON SERUM hsCRP LEVELS AND PERIODONTAL PARAMETERS IN SYSTEMICALLY HEALTHY YOUNG WOMEN WITH GINGIVITIS
Status: NOT_YET_RECRUITING
Conditions: Gingivitis
Interventions: PROCEDURE: SCALING
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Clinic-based Versus Self-use of Medical Abortion Pills
Status: COMPLETED
Conditions: Induced Abortion|First Trimester Abortion|Misoprostol|Mifepristone
Interventions: BEHAVIORAL: Medical abortion pills sourced from pharmacies|BEHAVIORAL: Medical abortion pills sourced from health clinics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Effect of the AI500™ SINGLE-DOSE GEL Medical Device in Patients With Reduced Knee Function
Status: COMPLETED
Conditions: Pain, Acute|Pain, Chronic|Knee Injuries|Knee Osteoarthritis|Knee Arthritis|Knee Pain Swelling
Interventions: DEVICE: AI 500™ SINGLE-DOSE GEL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-finding Trial of HCD122 in Patients With Chronic Lymphocytic Leukemia (CLL) That is Relapsed or Non-responsive to Prior Fludaribine Therapy
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: HCD122
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT