pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Randomized Study of New Formulation Ophthalmic Cysteamine Hydrochloride for Corneal Cystine Accumulation in Patients With Cystinosis
Status: COMPLETED
Conditions: Cystinosis
Interventions: DRUG: cysteamine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Two Types of Acupuncture on Autonomic Nervous Activity and Quality of Life in Women With Dysmenorrhea.
Status: UNKNOWN
Conditions: Dysmenorrhea
Interventions: OTHER: Manual Acupuncture|DEVICE: Laser Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corrected QT (QTc) Study With Flucticasone Furoate and GW642444
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone furoate (200 mcg)/GW642444 (25mcg) combination|DRUG: Fluticasone furoate (400 mcg)/GW642444 (50mcg) combination|DRUG: Placebo Inhaler|DRUG: Moxifloxacin 400mg|DRUG: Moxifloxacin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Artery Denervation for Treatment of Pulmonary Arterial Hypertension
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: PROCEDURE: denervation|PROCEDURE: sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of the Efficacy of Sirolimus (Rapamune®) in the Treatment of Severe Arteriovenous Malformations
Status: RECRUITING
Conditions: Arteriovenous Malformations
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibuprofen Versus Mecillinam for Uncomplicated Cystitis
Status: COMPLETED
Conditions: Acute Cystitis (Excl in Pregnancy)
Interventions: DRUG: Ibuprofen|DRUG: Mecillinam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reinvigorating TNBC Response to Immunotherapy With Combination Myeloid Inhibition and Radiation
Status: RECRUITING
Conditions: TNBC - Triple-Negative Breast Cancer|Breast Cancer
Interventions: DRUG: Pembrolizumab|RADIATION: Radiation Therapy|DRUG: Axatilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotine Pharmacokinetics From Research Electronic Nicotine Delivery System S-TA-U001 in Smokers and E-Cigarette Users
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: DRUG: Research ENDS S-TA-U001|DRUG: Nicorette Inhalator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study for Assessing the Efficacy and Safety of Tetrahydrobiopterin in Radiation-Induced Skin Injury
Status: UNKNOWN
Conditions: Radiation-Induced Dermatitis
Interventions: DRUG: Tetrahydrobiopterin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Dexketoprofen and Paracetamol in the Treatment of Headache Caused by Acute Migraine Attack
Status: COMPLETED
Conditions: Acute Migraine
Interventions: DRUG: Paracetamol|DRUG: Dexketoprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thyroid Hormone Replacement for Subclinical Hypothyroidism
Status: COMPLETED
Conditions: Subclinical Hypothyroidism
Interventions: DRUG: Levothyroxine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Mavrilimumab in Subjects With Moderate-to-Severe Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Mavrilimumab 30 mg|BIOLOGICAL: Mavrilimumab 100 mg|BIOLOGICAL: Mavrilimumab 150 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Efficacy and Safety Study in Adults With ADHD Using CTx-1301.
Status: COMPLETED
Conditions: ADHD|ADHD - Combined Type|Attention Deficit Hyperactivity Disorder Combined|Attention Deficit Hyperactivity Disorder
Interventions: DRUG: CTx-1301 - Dexmethylphenidate 25mg|DRUG: CTx-1301 - Dexmethylphenidate 37.5mg|DRUG: CTx-1301 - Dexmethylphenidate 50mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Relation of Ankle Mobility and Achilles Tendon, Plantar Fascia and Iliotibial Band Mechanical Properties
Status: COMPLETED
Conditions: Mobility Limitation|Stiffness of Right Ankle, Not Elsewhere Classified|Stiffness of Left Ankle, Not Elsewhere Classified|Tone Increased, Muscle
Interventions: DIAGNOSTIC_TEST: myotonometric assessment|DIAGNOSTIC_TEST: Ankle mobility assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: CAR T Cell Receptor Immunotherapy for Patients With B-cell Lymphoma
Status: COMPLETED
Conditions: Primary Mediastinal B-cell Lymphoma|Diffuse, Large B-cell Lymphoma|Diffuse Large B-Cell Lymphoma Transformed From Follicular Lymphoma|Mantle Cell
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|BIOLOGICAL: Anti-cluster of differentiation 19 (CD19)-CAR PBL|DRUG: Aldesleukin|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Compression Time for Secure Stapling With a Linear Stapler in Laparoscopic Gastric Bypass Surgery
Status: UNKNOWN
Conditions: Bleeding of the Staple Line
Interventions: PROCEDURE: compression time of the laparoscopic linear stapler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Licarbazepine in the Treatment of Manic Episodes of Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Licarbazepine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Doses of Nebulized Magnesium Sulphate in Status Asthmaticus
Status: COMPLETED
Conditions: Status Asthmaticus
Interventions: DRUG: Magnesium Sulfate 500 mg/ml+ ventolin|DRUG: Ventolin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Dose Adjusted EPOCH-R, to Treat Mature B Cell Malignancies
Status: COMPLETED
Conditions: Diffuse Large B Cell Lymphoma|Post Transplant Lymphoproliferative Disorder|Primary Mediastinal (Thymic) Large B-cell Lymphoma
Interventions: DRUG: DA-EPOCH-R for DLBCL, PTLD, AND PMBCL|DRUG: Methotrexate|DRUG: Etoposide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Prednisone|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Myeloid Leukemia (CML) Philadelphia Chromosome Positive
Interventions: DRUG: Imatinib|DRUG: Nilotinib|DRUG: Bosutinib|DRUG: Dasatinib|DRUG: Asciminib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ICMR-Indiaclen Trial on Amoxycillin vs Cotrimoxazole for Non-Severe Pneumonia
Status: COMPLETED
Conditions: Non-Severe Pneumonia|Under-Fives|Children
Interventions: DRUG: Oral Co-trimoxazole (8mg/kg/day trimithoprim) twice a day for five days vs. oral amoxycillin (20 mg/kg/day) thrice a day for three days.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement of Anti-TB Drugs in Lung Tissue From Patients Having Surgery to Treat Tuberculosis
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: Rifampicin|DRUG: Isoniazid|DRUG: Pyrazinamide|DRUG: Kanamycin|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acceptability and Feasibility in the Context of the IMPROVE Trial in Kenya
Status: COMPLETED
Conditions: Malaria in Pregnancy|Adherence, Treatment
Interventions: DRUG: Monthly intermittent preventive treatment with dihydroartemisnin-piperaquine|DRUG: Monthly intermittent preventive treatment with sulfadoxine-pyrimethamine|DRUG: Monthly intermittent preventive treatment with dihydroartemisnin-piperaquine with targeted information transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Monoclonal Antibody Therapy and/or Vaccine Therapy in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: BCG vaccine|BIOLOGICAL: monoclonal antibody 105AD7 anti-idiotype vaccine|DRUG: alum adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osteopathy and Physiotherapy Compared to Physiotherapy Alone on Fatigue and Functional Status in Long COVID
Status: RECRUITING
Conditions: Covid19|SARS-CoV-2 Infection
Interventions: OTHER: Osteopathic Manipulative Treatment in addition to Physiotherapy|OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Iloprost for the Treatment of Persistent Pulmonary Hypertension in the Term and Near Term Infants.
Status: TERMINATED
Conditions: Pulmonary Hypertension
Interventions: DRUG: Inhaled Iloprost
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Real-Time, Remote Monitoring System for Home-Based HIV Testing
Status: COMPLETED
Conditions: HIV
Interventions: BEHAVIORAL: "Smart" home-based test for HIV|BEHAVIORAL: Home-based testing only|BEHAVIORAL: Reminder letters for clinic-based testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nebulized Magnesium Sulfate in Children With Moderate to Severe Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: DRUG: Magnesium Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: World Health Organization (WHO) , COVID19 Case Series of Post Covid 19 Rhino Orbito Cerebral Mucormycosis in Egypt
Status: COMPLETED
Conditions: Mucormycosis; Rhinocerebral (Etiology)|COVID-19
Interventions: PROCEDURE: debridment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Adenocarcinoma|Endometrial Mixed Cell Adenocarcinoma|Endometrial Serous Adenocarcinoma|Endometrial Undifferentiated Carcinoma|Endometrioid Adenocarcinoma|Stage IV Uterine Corpus Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspirate|PROCEDURE: Bone Marrow Biopsy|DRUG: Capivasertib|DRUG: Cediranib|DRUG: Cediranib Maleate|PROCEDURE: Computed Tomography|BIOLOGICAL: Durvalumab|PROCEDURE: Echocardiography|PROCEDURE: Multigated Acquisition Scan|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRP-HA Versus HA in Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: Hyaluronic acid (Synolis VA)|BIOLOGICAL: Cellular Matrix platelet-rich-plasma with hyaluronic acid (CM PRP-HA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Topical Formulations Containing Clindamycin and Clotrimazole in Patients With Vaginal Infections
Status: COMPLETED
Conditions: Vaginal Infections
Interventions: DRUG: ClinSupV3 -soft gelatin capsule|DRUG: ClinSupV3ER- Extended release tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of Dexanabinol in Patients With Advanced Solid Tumours
Status: COMPLETED
Conditions: Solid Tumour
Interventions: DRUG: Dexanabinol|OTHER: Cremophor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alleviating Burden of Chronic Musculoskeletal Pain in the Emergency Department
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain
Interventions: BEHAVIORAL: P.E.A.K. Rx|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Asthma Intervention Research (AIR) Trial
Status: COMPLETED
Conditions: Asthma
Interventions: PROCEDURE: Bronchial thermoplasty with the Alair System|DRUG: Conventional therapy with ICS+LABA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Adjunctive Therapies in Regenerative Treatment of Stage III Grade C Periodontitis
Status: COMPLETED
Conditions: Periodontitis|Lasers|Ozone|Wound Healing|Regeneration
Interventions: DEVICE: Control group|DEVICE: Antimicrobial photodynamic therapy (aPDT) group|DEVICE: LED photobiomodulation group|DEVICE: Topical ozone group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasonography Assessment of Peripheral Entheses in Axial Spondyloarthritis and in Healthy Subjects, Athletes or Not
Status: COMPLETED
Conditions: Peripheral Entheses
Interventions: BIOLOGICAL: BLOOD SAMPLES|DEVICE: Radiographs of the sacroiliac joints|DEVICE: Radiographs of heels|DEVICE: SCAN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Pharmacokinetics of Sancuso and IV Granisetron in Patients Aged 2 to 5 Years
Status: WITHDRAWN
Conditions: Chemotherapy Induced Nausea and Vomiting
Interventions: DRUG: Sancuso|DRUG: IV granisetron
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Multifactorial Intervention on Frailty
Status: COMPLETED
Conditions: Frail Elderly|Cognitive Impairment|Dependence
Interventions: OTHER: Multifactorial intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Severity of Fecal Incontinence and Manometric Values Using the Anopress® Device in Women
Status: COMPLETED
Conditions: Fecal Incontinence|Anal; Sphincter, Incontinence|Incontinence, Urge
Interventions: DIAGNOSTIC_TEST: Portable endoanal manometry|DIAGNOSTIC_TEST: Endoanal ultrasound|OTHER: Incontinence severity scale questionaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mechanisms of Resistance to Amivantamab in Patients With NSCLC With EGFR Exon 20 Insertion
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|EGFR Exon 20 Insertion Mutation
Interventions: PROCEDURE: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Compartive Evalution of the Efficiency of Maxillary Canine Retraction Using Power Chain Versus Burstone T-loop
Status: ACTIVE_NOT_RECRUITING
Conditions: Class I Malocclusion
Interventions: DEVICE: BURSTONE T-LOOP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cervical Block on Recurrent Laryngeal Nerve Monitoring During Thyroid Surgery
Status: UNKNOWN
Conditions: Thyroid Surgery
Interventions: DRUG: Intermediate cervical block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluating the Safety and Immunogenicity of a Live Attenuated West Nile Virus Vaccine for West Nile Encephalitis in Adults 50 to 65 Years of Age
Status: COMPLETED
Conditions: West Nile Virus
Interventions: BIOLOGICAL: WN/DEN4Δ30 Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of BMS-986393 a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: BMS-986393
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Epidemiology of Pediatric Germ Cell Tumors
Status: RECRUITING
Conditions: Germ Cell Tumor|Germinoma|Teratoma|Embryonal Carcinoma|Yolk Sac Tumor|Choriocarcinoma|Mixed Germ Cell Tumor|Late Effects|Pediatric Germ Cell Tumor
Interventions: OTHER: Questionnaire Administration|OTHER: Tumor Specimen Collection|OTHER: Germline DNA Samples|PROCEDURE: Blood Sample Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Testing Lenvatinib and Cetuximab in Patients With Advanced Head and Neck Squamous Cell Carcinoma and Cutaneous Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma|Cutaneous Squamous Cell Carcinoma|Head and Neck Cancer|Head and Neck Carcinoma
Interventions: DRUG: Lenvatinib Pill|DRUG: Lenvatinib Pill|DRUG: Lenvatinib Pill|DRUG: Cetuximab|DRUG: Lenvatinib Pill|DRUG: Lenvatinib Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Usefulness of Probe-based Confocal Laser Endo-microscopy in Delineation of Margin of Early Gastric Cancer for Endoscopic Submucosal Dissection
Status: COMPLETED
Conditions: Early Gastric Cancer
Interventions: DEVICE: Endoscopic submucosal dissection (ESD) with or without probe-based confocal laser endomicroscopy (pCLE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Cognitive Processing Therapy for Posttraumatic Stress Disorder Via Stellate Ganglion Block Treatment: A Pilot Trial
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder|Chronic Pain
Interventions: PROCEDURE: Stellate Ganglion Block Treatment|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Involvement of Reticulum Endoplasmic Stress in the Physiopathology of Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Metformin|DIETARY_SUPPLEMENT: Myo-inositol + folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vafseo Outcomes In-Center Experience
Status: NOT_YET_RECRUITING
Conditions: Anemia of Chronic Kidney Disease
Interventions: DRUG: Vadadustat|DRUG: Erythropoiesis Stimulating Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Study With PRAM of the Cardiovascular Response to the Positioning of the Extraglottic Device
Status: UNKNOWN
Conditions: Intubation Complication|Hemodynamic Instability
Interventions: DEVICE: airway management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess Relative Bioavailability and Food Effect of ABBV-668 Extended-Release Formulations in Adult Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: ABBV-668 IR|DRUG: ABBV-668 ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chronic Hypertension and Acetyl Salicylic Acid in Pregnancy
Status: RECRUITING
Conditions: Chronic Hypertension Complicating Pregnancy|Pre-Eclampsia|Intrauterine Growth Restriction|Aspirin|Perinatal Death|Placental Abruption
Interventions: DRUG: Aspirin 150 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Silq Urinary Catheter
Status: ACTIVE_NOT_RECRUITING
Conditions: Biofilm Formation|UTI
Interventions: DEVICE: Long-term indwelling Foley catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prediction Medical Device for Rheumatoid Arthritis (PREDIRA)
Status: UNKNOWN
Conditions: Arthritis, Rheumatoid
Interventions: DEVICE: SinnoTest®|OTHER: Biotherapy prescription without SinnoTest® software
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Measure the Maximun HR After ReConnect ® Supplementation vs. Placebo in CFS.
Status: COMPLETED
Conditions: Chronic Fatigue Syndrome
Interventions: DIETARY_SUPPLEMENT: ReConnect (NADH plus CoQ10)|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Modifications for the Treatment of Sarcopenic Obesity
Status: UNKNOWN
Conditions: Sarcopenic Obesity|Sarcopenia|Obesity
Interventions: DIETARY_SUPPLEMENT: Protein Drink/Diet|BEHAVIORAL: Exercise|DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Diabetes in Overweight/Obese Preadolescent Children
Status: COMPLETED
Conditions: Overweight Children With Type 2 Diabetes Risk
Interventions: BEHAVIORAL: lifestyle and psycho-educational program|OTHER: Exercise plus lifestyle and psycho-educational program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Flaxseed Flour in Appetite Sensations, Lipid Profile and Pressure Levels Among Overweighed and Obese Women
Status: COMPLETED
Conditions: Adult Women|Overweight|Obese
Interventions: DIETARY_SUPPLEMENT: Defatted flaxseed flour|DIETARY_SUPPLEMENT: Golden flaxseed flour|DIETARY_SUPPLEMENT: Whole brown flaxseed flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of CSJ148 in Stem Cell Transplant Patients
Status: COMPLETED
Conditions: HCMV
Interventions: BIOLOGICAL: CSJ148|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Psycho-educational Program on Climate Change Distress and Risk Perception Among Older Adults.
Status: COMPLETED
Conditions: Psycho-educational Programو Climate Change Distressو Risk Perception, Older Adults
Interventions: BEHAVIORAL: Psycho-educational Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cardiovascular Effects of Heated Tobacco Products (HTP)
Status: COMPLETED
Conditions: Heated Tobacco Products|Microcirculation|Thrombosis|Vascular Function|Blood Markers|Microvesicles|NETs
Interventions: OTHER: HTP inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Pharmacokinetics and Pharmacodynamics of Canagliflozin (JNJ-28431754) in Healthy Indian Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Canagliflozin (JNJ-28431754) 200 mg|DRUG: Canagliflozin (JNJ-28431754) 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Follow-up Study Investigating Long Term Treatment With Nintedanib in Patients With Progressive Fibrosing Interstitial Lung Disease (PF-ILD)
Status: COMPLETED
Conditions: Lung Diseases, Interstitial
Interventions: DRUG: Nintedanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of NIMV on the Health Status of Chronic Obstructive Pulmonary Disease (COPD )Patients
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: non-invasive mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Estradiol/Norethindrone Acetate Tablets, 1/0.5 mg Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Estradiol/Norethindrone acetate|DRUG: Activella®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Connected Rehabilitation: an Alternative to Conventional Cardiovascular Rehabilitation?
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: OTHER: Conventional CVR programme|OTHER: Connected CVR programme|OTHER: Follow-up visit M2|OTHER: Follow-up vsit M8
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimizing Pain During Office Intradetrussor Botox Injection
Status: COMPLETED
Conditions: Overactive Bladder|Overactive Detrusor|Overactive Bladder Syndrome|Overactivity; Behavior|Urge Incontinence
Interventions: DRUG: Bicarbonate protocol|DRUG: Standard protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Stimulation on Central Nervous System Excitability
Status: UNKNOWN
Conditions: Healthy
Interventions: DEVICE: anodal tsDCS|DEVICE: cathodal tsDCS|DEVICE: sham tsDCS|DEVICE: Gait training|DEVICE: High frequency rTMS|DEVICE: Low frequency rTMS|DEVICE: sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind, Placebo-controlled, Multicenter Clinical Trial to Evaluate the Clinical Efficacy and Safety of Yogliptin Tablets
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: placebo group|DRUG: Yogliptin 400mg group|DRUG: Yogliptin 200mg group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Bimatoprost 0.01% Alone Compared With Travoprost 0.004% and Timolol 0.5% in Subjects With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: bimatoprost 0.01%|DRUG: travatan 0.004%|DRUG: timolol 0.5%|DRUG: hypromellose 0.3%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Roxadustat in the Treatment of Anemia in Participants With ESRD on Stable Dialysis
Status: COMPLETED
Conditions: CKD Anemia in Stable Dialysis Patients
Interventions: DRUG: Epoetin Alfa|DRUG: Roxadustat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Memory in Mild Cognitive Impairment and Early Stage Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease|Mild Cognitive Impairment
Interventions: DEVICE: North Coast Medical Activadose II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proof-of-Concept Superiority Trial of Fosravuconazole Versus Itraconazole for Eumycetoma in Sudan
Status: COMPLETED
Conditions: Mycetoma
Interventions: DRUG: Fosravuconazole|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Nevirapine and Efavirenz for the Treatment of HIV-TB Co-infected Patients (ANRS 12146 CARINEMO)
Status: COMPLETED
Conditions: Tuberculosis|Aids|Hiv Infections
Interventions: DRUG: Nevirapine based therapy|DRUG: Efavirenz based therapy|DRUG: Rifampicin (RMP) Ethambutol (E) Isoniazid (H) Pyrazinamid (Z)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Metformin Activity in Addition to Conventional Treatment of Grade II or III Pulmonary Arterial Hypertension (PAH)
Status: WITHDRAWN
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Magnesium Oral Supplementation to Reduce Pain Inpatients With Severe Peripheral Arterial Occlusive Disease
Status: UNKNOWN
Conditions: Peripheral Arterial Disease
Interventions: DIETARY_SUPPLEMENT: Magnesium oxide|DIETARY_SUPPLEMENT: Fructose|DRUG: Oxycodone|DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study About the Effect of Doxycycline and Acetylcystein in the Treatment of CD-associated Fistulae
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: PROCEDURE: Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Arteriovenous Vascular (AV) ACCESS Trial
Status: RECRUITING
Conditions: End-Stage Kidney Disease|Hemodialysis Complication
Interventions: DEVICE: AV graft|PROCEDURE: surgical intervention for creation of a fistula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Intravenous Immunoglobulin Therapy for Severe 2019-nCoV Infected Pneumonia
Status: UNKNOWN
Conditions: 2019-nCoV
Interventions: DRUG: Intravenous Immunoglobulin|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunosuppression Management in Renal Transplant Recipients With Transplant Excellence Based on TruGraf Test
Status: UNKNOWN
Conditions: Kidney Transplant Rejection|Immunosuppression
Interventions: DIAGNOSTIC_TEST: TruGraf|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Maternal Role in Oral Feed Establishment in Preterm Neonates
Status: UNKNOWN
Conditions: Preterm Birth|Tube Feeding|Swallowing Disorder|Maternal Care Patterns
Interventions: OTHER: perioral sensory motor stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Real-time MRI Right Heart Catheterization Using Passive Catheters
Status: COMPLETED
Conditions: Caridovascular Disease|Congenital Heart Disease|Pulmonary Hypertension
Interventions: PROCEDURE: Cardiac Real-time MRI RHC (Right Heart Catheterization)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of 3 Ropivacaine Suprascapular Nerve Blocks in Subacute Adhesive Capsulitis: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Adhesive Capsulitis|Frozen Shoulder|Nerve Block
Interventions: DRUG: Ropivacaine Monohydrochloride|DRUG: Placebo - Concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of STI571 in the Treatment of Patients With Idiopathic Hypereosinophilic Syndrome (HES) and Eosinophilic Leukemias
Status: UNKNOWN
Conditions: Hypereosinophilic Syndrome|Chronic Eosinophilic Leukemia (CEL)|Myeloproliferative Disorders
Interventions: DRUG: STI571
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Clinical Study of Curcuvail® in Patients With Non-alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Fatty Liver Without Mention of Alcohol
Interventions: DRUG: Test Product: Curcuvail® 250mg capsule (Curcuma longa Extractcontaining 35% Curcuminoids)|DRUG: Placebo product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Retinal Oxygenation Estimation Trial With Mantis Photonics Hyperspectral Camera
Status: ENROLLING_BY_INVITATION
Conditions: Glaucoma Eye|Macular Degeneration|Macula Abnormality|Retinal Detachment
Interventions: DEVICE: Hyperspectral retinal image|DRUG: Mydriacyl Ophthalmic Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Suicide Prevention by Lithium - the Lithium Intervention Study
Status: TERMINATED
Conditions: Suicide|Depressive Disorders
Interventions: DRUG: lithium|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective, Non-randomized Multi-center, Controlled Physician-initiated Trial: Rotarex Belgium In-stent Occlusion
Status: COMPLETED
Conditions: Peripheral Vascular Disease
Interventions: DEVICE: Rotarex S
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility Study of XAF5 Gel for Reduction of Submental Fat
Status: SUSPENDED
Conditions: Excess Submental Fat ("Double Chin")
Interventions: DRUG: XAF5 Gel|DRUG: Placebo Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Siltuximab to Decrease Symptom Burden After Autologous Stem Cell Transplantation for Patients With Multiple Myeloma and AL Amyloidosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma|AL Amyloidosis
Interventions: DRUG: Siltuximab|BEHAVIORAL: The M.D. Anderson Symptom Inventory (MDASI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase IIb Study of AZD5462 in Patients With Chronic Heart Failure
Status: RECRUITING
Conditions: Chronic Heart Failure
Interventions: DRUG: AZD5462|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double-blind, Placebo-Controlled, Efficacy Study of a New Formulation of Phenylephrine HCL in the Common Cold
Status: TERMINATED
Conditions: Common Cold
Interventions: DRUG: New Formulation Phenylephrine HCl|DRUG: Marketed Phenylephrine HCl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RACE-CARS - RAndomized Cluster Evaluation of Cardiac ARrest Systems
Status: ENROLLING_BY_INVITATION
Conditions: Cardiac Arrest
Interventions: OTHER: Rapid cardiac arrest recognition that triggers immediate priority EMS/first responder dispatch by 911 operators|OTHER: Systematic bystander resuscitation instruction by 911 operators|OTHER: Comprehensive community training of lay people in CPR and AED use.|OTHER: Optimized first responder performance including earlier use of AEDs.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Fish Oil Supplementation During Pregnancy for Prevention of Asthma, Eczema and Allergies in Childhood
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma|Eczema|Allergy
Interventions: DIETARY_SUPPLEMENT: n-3 fatty acid|DIETARY_SUPPLEMENT: olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Objectively Diagnose and Monitor Treatment of Light Sensitivity
Status: RECRUITING
Conditions: Photophobia|Traumatic Brain Injury|Migraine
Interventions: DEVICE: Pupillography|DEVICE: Ocular Coherence Tomography (OCT)|DEVICE: Wrist-watch sensor device|DEVICE: Videography|DEVICE: Electrophysiology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Labial Mucosal Epithelium Grafting for Corneal Limbus Substitution
Status: RECRUITING
Conditions: Limbal Stem-cell Deficiency
Interventions: PROCEDURE: Labial mucosal epithelium grafting for corneal limbus substitution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Duloxetine - Warfarin Pharmacodynamic Study
Status: COMPLETED
Conditions: Anticoagulant Effect of Warfarin When Taken With Duloxetine.
Interventions: DRUG: Duloxetine|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Predictive Factors for the Effectiveness of the Ilioinguinal Iliohypogastric Nerve Block for Hernia Surgery
Status: RECRUITING
Conditions: Hernia Inguinal|Pain Postoperative|Regional Anesthesia
Interventions: OTHER: Ilioinguinal-Iliohypogastric nerve block|DRUG: Local anesthetic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Immunogenicity of a Sub-unit Protein CD40.RBDv Bivalent COVID-19 Vaccine, Adjuvanted or Not, as a Booster in Volunteers.
Status: RECRUITING
Conditions: COVID-19
Interventions: DRUG: CD40.RBDv vaccin (SARS-Cov2 Vaccin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Local Co-administration of Autologous ADIpose Derived Stromal Vascular Fraction With Microfat for Refractory Perianal CROHN's Fistulas.
Status: UNKNOWN
Conditions: Crohn Disease
Interventions: COMBINATION_PRODUCT: local co-administration of autologous ADIpose|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Weight Loss Diet Study: Low Carb vs Low Fat
Status: COMPLETED
Conditions: Obesity|Insulin Resistance
Interventions: BEHAVIORAL: Low-Carbohydrate Diet|BEHAVIORAL: Low-Fat Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Significance of Alveolar Recruitment Maneuver During Bariatric Surgery
Status: COMPLETED
Conditions: Obesity
Interventions: PROCEDURE: Anesthesia: alveolar recruitment maneuver|PROCEDURE: Anesthesia: standardized
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Is a Woolen Cap Effective in Maintaining Normothermia in Preterm Infants During Kangaroo Mother Care?
Status: COMPLETED
Conditions: Neonatal Temperature; Kangaroo Mother Care
Interventions: OTHER: Woolen cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Traveler's Diarrhea
Status: COMPLETED
Conditions: Diarrhea
Interventions: DIETARY_SUPPLEMENT: Probiotical|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing Autologous Peripheral Blood Stem Cell to Bone Marrow Transplantation for Recurrent Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: PROCEDURE: PBSCT|PROCEDURE: Bone Marrow Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real-World Efficacy of Evoke® Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy in Chronic Pain Patients (ULTRA).
Status: RECRUITING
Conditions: Pain|Chronic Pain|Neuropathic Pain
Interventions: DEVICE: Evoke
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Pilot Study on Budesonide/Formoterol Device-metered Dry Powder Inhaler
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Budesonide/Formoterol Batch 1|DRUG: Budesonide/Formoterol Batch 2|DRUG: Budesonide/Formoterol Batch 1 and charcoal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study Assessing a Range of Formulations of the Fixed Dose Combination Product Containing Dutasteride (0.5mg) and Tamsulosin Hydrochloride (0.2mg) to Find a Formulation Which is Bioequivalent to Harnal-D Tablets (Tamsulosin Hydrochloride, 0.2mg) in Healthy Male Subjects From North East Asia
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: DRUG: Dutasteride (0.5mg, fasted state)|DRUG: Dutasteride (0.5mg, fed state)|DRUG: Fixed dose combination capsule containing dutasteride 0.5mg and tamsulosin 0.2mg (fasted state)|DRUG: Fixed dose combination capsule containing dutasteride 0.5mg and tamsulosin 0.2mg (fasted state)|DRUG: Fixed dose combination capsule containing dutasteride 0.5mg and tamsulosin 0.2mg (fasted state)|DRUG: Fixed dose combination capsule containing dutasteride 0.5mg and tamsulosin 0.2mg (fed state)|DRUG: Harnal-D Tablets with water (fasted state)|DRUG: Harnal-D Tablets with water (fed state)|DRUG: Harnal-D tablets without water (fasted state)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO5545965 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: RO5545965|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Study of Amniotic Membrane Graft in the Management of Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot|Foot Ulcer; Diabetic
Interventions: DEVICE: Offloading|PROCEDURE: Dressing Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GvHD Prophylaxis in Unrelated Donor HCT: Randomized Trial Comparing PTCY Versus ATG
Status: RECRUITING
Conditions: Graft Vs Host Disease|Peripheral Blood Stem Cell Transplantation|AML|MDS|MDS/MPN|CMML
Interventions: DRUG: Cyclophosphamide|BIOLOGICAL: ATG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: RECOVER-VITAL: Platform Protocol, Appendix to Measure the Effects of Paxlovid on Long COVID Symptoms
Status: RECRUITING
Conditions: Long COVID-19|Long COVID
Interventions: DRUG: Paxlovid 25 day dosing|DRUG: Paxlovid 15 day dosing|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficiency of the PacePress to Prevent Hemorrhagic Complications in Patients Undergoing CIED Implantation.
Status: RECRUITING
Conditions: Hemorrhagic Complications|Hematoma|Hemorrhage|Pathologic Processes
Interventions: DEVICE: PacePress|DEVICE: standard compression band
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION