pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: SAGE for the Early Detection of Cognitive Impairment at Primary Care Provider Visits
Status: COMPLETED
Conditions: Cognitive Impairment
Interventions: OTHER: Self-Administered Gerocognitive Examination (SAGE) or Electronic Self-Administered Gerocognitive Examination (eSAGE)|OTHER: Informant Conversation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Population Pharmacokinetics Study of Tigecycline and Pharmacokinetics- Pharmacodynamics Index in Patients With Carbapenem Resistant Enterobacteriaceae Bloodstream Infection
Status: RECRUITING
Conditions: Carbapenem-resistant Enterobacteriaceae
Interventions: OTHER: Collect blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Low Carbohydrate Diet on Liver Fat Content and Mitochondrial Fluxes
Status: ACTIVE_NOT_RECRUITING
Conditions: Fatty Liver
Interventions: BEHAVIORAL: Low Carbohydrate Diet|BEHAVIORAL: Simple Calorie Restriction Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tipifarnib and Etoposide in Treating Older Patients With Newly Diagnosed, Previously Untreated Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome|Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Secondary Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: tipifarnib|DRUG: etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study on the Efficacy and Safety of VEC Intravenous Chemotherapy Combined With Conbercept Intravitreal Injection in the Treatment of Retinoblastoma
Status: UNKNOWN
Conditions: Retinoblastoma
Interventions: DRUG: Conbercept ophthalmic injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Very Low Dose Oral Anticoagulation and Thromboembolic and Bleeding Complications
Status: TERMINATED
Conditions: Mechanical Heart Valve Recipients
Interventions: DRUG: phenprocoumon|DRUG: phenprocoumon|DRUG: phenprocoumon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Oral BT-11 in Healthy Adult Male and Female Volunteers
Status: COMPLETED
Conditions: Normal Healthy Volunteers
Interventions: DRUG: Placebo|DRUG: BT-11
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Forecasting and Preventing Post-Bariatric Hypoglycaemia WP 2
Status: COMPLETED
Conditions: Post-bariatric Hypoglycaemia|Roux-en-Y Gastric Bypass
Interventions: OTHER: 15 g dextrose|OTHER: 5 g dextrose|OTHER: Protein bar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility Study of the RF Ablation Catheter to Ablate Lung Tumors
Status: TERMINATED
Conditions: Lung Cancer|Lung Cancer Metastatic|Lung Cancer, Non-small Cell
Interventions: DEVICE: Radio-frequency Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Comparing of Modified Wet Suction Technique and Dry Suction Technique for EUS-FNA of Solid Occupying Lesions
Status: UNKNOWN
Conditions: Pancreas Neoplasms|Lymphatic Metastasis|Neoplasm Metastases|Unknown Primary Neoplasm Metastasis|Infection|Inflammation|Sarcoid|Lymphadenopathy
Interventions: PROCEDURE: the first pass is made with 5ml suction technique|PROCEDURE: the first pass is made with modified wet suction technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Antimalarial Drugs to Rabies Vaccine for Post-exposure Prophylaxis.
Status: COMPLETED
Conditions: Rabies
Interventions: DRUG: Chloroquine|DRUG: Atovaquone and Proguanil|DRUG: Doxycycline|BIOLOGICAL: Rabies Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reduced Intra-operative Blood Loss in Pancreaticoduodenectomy for Pancreatic or Peri-ampullary Tumors; Monocentric Trial on Standard Open Versus Minimally Invasive Surgery
Status: WITHDRAWN
Conditions: Surgery|Pancreatic Tumour|Peri-ampullary Tumour|Blood Loss
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial Evaluating Both Tolerability and Improvement for Signs of Facial Photoaging, Discoloration, and Texture in Adult Females of All Skin Types by Combining a Placebo Moisturizer and Non-ablative Laser.
Status: RECRUITING
Conditions: Photoaging
Interventions: DEVICE: LaseMD Laser|DEVICE: Sciton Laser|DRUG: Phyto A+ Brightening Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Analgesic Efficacy of Erector Spinae Block in Comparison to Thoracic Epidural Anesthesia in Oesophageal Surgeries
Status: COMPLETED
Conditions: Analgesic Efficacy
Interventions: DEVICE: bilateral erector spinae block|DEVICE: Thoracic epidural anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PleuraSeal Post Market Study (Europe)
Status: COMPLETED
Conditions: Lung Disease|Pulmonary Lobectomy
Interventions: PROCEDURE: Standard Tissue Closure Techniques|DEVICE: PleuraSeal Lung Sealant System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Transmission of Artemisinin Resistant Parasites Before and After Conventional Artemisinin-combination Therapy
Status: RECRUITING
Conditions: Falciparum; Malaria
Interventions: DRUG: Artemether-lumefantrine|DRUG: Dihydroartemisinin-Piperaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy, Safety & Tolerability of Serlopitant for Pruritus (Itch) After Burn Injury
Status: TERMINATED
Conditions: Pruritus|Burns
Interventions: DRUG: Serlopitant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Complication of Pancreatic Fistula and Bleeding After Pancreaticoduodenectomy in Treatment Periampullary Cancer
Status: COMPLETED
Conditions: Periampullary Cancer|Pancreatic Fistula|Bleeding
Interventions: PROCEDURE: Pancreaticoduodenectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optimization of Preoperative Treatment in Locally Advanced Rectal Cancer
Status: RECRUITING
Conditions: Cancer, Rectum
Interventions: RADIATION: Short-course radiotherapy with neoadjuvant chemotherapy|RADIATION: Long-term chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effects of Omega-3 Fatty Acids on Heart Disease and Behavior
Status: COMPLETED
Conditions: Cardiovascular Diseases|Mood Disorders|Inflammation
Interventions: DIETARY_SUPPLEMENT: Fish Oil|DIETARY_SUPPLEMENT: Soybean Oil (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dexilant Treatment in Gastrointestinal Reflux Disease (GERD Related Non Cardiac Chest Pain
Status: WITHDRAWN
Conditions: Chest Pain|Gastrointestinal Reflux Disease
Interventions: DRUG: Dexilant|DRUG: Dexilant Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Melphalan and Dexamethasone Compared With High-Dose Melphalan Followed By Autologous Stem Cell Transplant in Treating Patients With Primary Systemic Amyloidosis
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: filgrastim|DRUG: dexamethasone|DRUG: melphalan|PROCEDURE: autologous hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Determine the Bioavailability of Oral Beta-Aminoisobutyric Acid (BAIBA) Ingestion
Status: COMPLETED
Conditions: Absorption; Chemicals
Interventions: DIETARY_SUPPLEMENT: Beta-Aminoisobutyric Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Trichuris Suis Ova (TSO) as Compared to Placebo
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: Trichuris suis ova (TSO)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Different Behaviour Change Techniques in MyPlan 2.0
Status: COMPLETED
Conditions: Disease, Chronic
Interventions: BEHAVIORAL: Action planning|BEHAVIORAL: Coping planning|BEHAVIORAL: Self-monitoring|BEHAVIORAL: Feedback and tips
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The First Failure Study
Status: TERMINATED
Conditions: HIV|HIV Infections
Interventions: DRUG: Darunavir, Ritonavir, Truvada|DRUG: Darunavir, Ritonavir and Etravirine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Urinary Tract Infection Rates Using a Controlled Aseptic Protocol for Catheter Insertion
Status: COMPLETED
Conditions: Urinary Tract Infections|Catheter Infection|Catheter-Related Infections
Interventions: DRUG: Catheter insertion with Povidone Iodine|PROCEDURE: Standard of care catheter insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Project THINK: Trajectories of Health, Ingestive Behaviors, and Neurocognition in Kids
Status: RECRUITING
Conditions: Pediatric Obesity|Binge-Eating Disorder
Interventions: BEHAVIORAL: Observational (not including MRI scanning)|BEHAVIORAL: Observational (including MRI scanning)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Long-term Efficacy and Safety of Monofocal Plate Haptic Intraocular Lens
Status: RECRUITING
Conditions: Lens Implantation, Intraocular|Cataract
Interventions: DEVICE: Acriva BB UDM 611
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MITO 35B: Olaparib Beyond Progression Compared to Platinum Chemotherapy After Secondary Cytoreductive Surgery in Recurrent Ovarian Cancer Patients.
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Olaparib|DRUG: Chemotherapy drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of the House Advancement Flap, Rhomboid Flap, and Y-V Anoplasty
Status: COMPLETED
Conditions: Anal Stenosis
Interventions: PROCEDURE: house advancement flap group|PROCEDURE: Rhomboid flap GROUP|PROCEDURE: Y-V anoplasty GROUP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Allopurinol on Markers of Mineral and Bone Metabolism
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Kidney Diseases|Osteodystrophy|Uric Acid Concentration, Serum, Quantitative Trait Locus 7
Interventions: DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Advancing People of Color in Clinical Trials Now: Involvement in Trials Using a Patient-Centered Website: A Community-Engaged Approach
Status: COMPLETED
Conditions: Recruitment
Interventions: BEHAVIORAL: Tailored Website|BEHAVIORAL: Standard Website
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Personalized GI Motility Responses to Diet
Status: RECRUITING
Conditions: Nutritional and Metabolic Diseases|Gastrointestinal Dysfunction|Cardiovascular Diseases|Dysbiosis
Interventions: OTHER: Whole grain rye bread|OTHER: Refined grain rye bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pain in Newborn Heel Blood Collection
Status: COMPLETED
Conditions: Infant, Newborn, Disease|Pain, Acute
Interventions: OTHER: White Noise|OTHER: Yakson Touch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fascia Iliaca Block for Post-Operative Pain Control After Total Hip Arthroplasty
Status: TERMINATED
Conditions: Osteoarthritis of the Hip
Interventions: DRUG: Ropivacaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine,Ketamine and Their Combination to Bupivicaine on Thoracic Epidural Analgesia
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Ketamine, bupivacine,dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Increased IV Hydration on Nulliparous Women Undergoing an Induction of Labor
Status: COMPLETED
Conditions: Labor; Forced or Induced, Affecting Fetus or Newborn
Interventions: DRUG: Intravenous normal saline administered at 250ml/hr|DRUG: Intravenous normal saline administered at 125ml/hr
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anesthetic Efficacy of Liposomal Prilocaine in Maxillary Infiltration Anesthesia
Status: COMPLETED
Conditions: Dental Anesthesia Efficacy
Interventions: DRUG: Prilocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety of a Single Dose of Moxidectin Compared With Ivermectin in Individuals Living in Onchocerciasis Endemic Areas and in Individuals Living in Onchocerciasis Endemic Areas With High Levels of Lymphatic Filariasis Co-endemicity Receiving Concomitant Albendazole
Status: ACTIVE_NOT_RECRUITING
Conditions: Onchocerciasis
Interventions: DRUG: Moxidectin|DRUG: Ivermectin|DRUG: Albendazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency and Pelvic Organ Prolapse
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse
Interventions: DEVICE: Non-ablative radiofrequency application|OTHER: Usual intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Liraglutide on the Cognitive Function in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: How Well Ethiopian Parents Assess and Manage Their Children's Postoperative Pain: Descriptive Correlational Study
Status: COMPLETED
Conditions: Parent|Pain|Ethiopia|Hospital
Interventions: PROCEDURE: This descriptive correlational study was conducted among 102 parents with children aged between 2 and 12 undergoing elective surgical procedures.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Loteprednol Etabonate Ophthalmic Ointment vs. Vehicle in the Treatment of Inflammation Following Cataract Surgery
Status: COMPLETED
Conditions: Ocular Inflammation
Interventions: DRUG: 0.5% Loteprednol Etabonate Ophthalmic Ointment|DRUG: Vehicle of Loteprednol Etabonate Ophthalmic Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PRevention Of Methamphetamine Use Among Postpartum Women Trial (PROMPT)
Status: RECRUITING
Conditions: Methamphetamine-dependence|Postpartum Abstinence
Interventions: DRUG: Progesterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Benign Paroxysmal Positional Vertigo (BPPV) in Nursing Homes: Treatment Efficacy and Impact on Balance, Gait and Falls
Status: UNKNOWN
Conditions: BPPV
Interventions: OTHER: repositioning maneuvers|OTHER: balance
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: the PrEsentation, Rationale and Impact of reperFUSION for Acute Coronary Syndromes in Cape Town and the Garden Route Health District - the PERFUSION Registry
Status: COMPLETED
Conditions: Acute Coronary Syndrome|ST Elevated Myocardial Infarction|Non ST Elevation Myocardial Infarction|Unstable Angina
Interventions: OTHER: No Intervention - Observational Registry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating Mass Spectrometry And Intraoperative MRI In The Advanced Multimodality Image Guided Operating Suite (Amigo) In Breast-Conserving Therapy
Status: COMPLETED
Conditions: Early Stage Breast Cancer|Breast Cancer Stage I|Breast Cancer Stage II
Interventions: PROCEDURE: Intra-operative Magnetic Resonance Imaging (MRI)|OTHER: Mass Spectrometer Analysis of Tissue Sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Cashew Nuts in the Human Diet: Measured Energy Value and Effects on Cardiovascular Disease Risk Factors
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: Base Diet|OTHER: Base Diet with Cashew Nuts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Individual PE vs Couples' CBT for Combat-Related Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: PTSD|Marital Relationship
Interventions: BEHAVIORAL: CBCT for PTSD|BEHAVIORAL: Prolonged Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personality, Defences, Central Sensitization, and Trauma in Women With Chronic Migraine, Fibromyalgia, and Vulvodynia
Status: RECRUITING
Conditions: Fibromyalgia|Chronic Migraine, Headache|Vulvodynia
Interventions: OTHER: Psychological self-reported measures assesment (questionnaire)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Testing of NBIA Genes: Analysis of Genetic Heterogeneity and Validation of Mitochondrial Markers for Assessing Causality of Sequence Variants.
Status: COMPLETED
Conditions: Neurodegeneration With Brain Iron Accumulation (NBIA)
Interventions: GENETIC: Establishment of mitochondrial markers|GENETIC: Sequencing tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Aerobic Exercises With Selected Phytoestrogens on Hot Flushes in Menopausal Women
Status: UNKNOWN
Conditions: Hot Flashes
Interventions: BEHAVIORAL: Aerobic excercise|DIETARY_SUPPLEMENT: soy products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma Multiforme|Glioblastoma|Glioblastoma Multiforme, Adult|Glioma|Brain Tumor|Brain Tumor, Recurrent|Neoplasms|Neoplasms, Nerve Tissue
Interventions: DRUG: Bevacizumab|DRUG: Microbubble|DEVICE: Low-Intensity Focused Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Tocilizumab Optimization Timing for CART19 Associated Cytokine Release Syndrome
Status: COMPLETED
Conditions: Lymphoblastic Leukemia, Acute, Childhood
Interventions: DRUG: Tocilizumab|DRUG: Tocilizumab|BIOLOGICAL: CART 19
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind Comparison of Concerta and Placebo in Adults With Attention Deficit Hyperactivity Disorder
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: methylphenidate HCl (Concerta)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Plazomicin Compared With Colistin in Patients With Infection Due to Carbapenem-Resistant Enterobacteriaceae (CRE)
Status: COMPLETED
Conditions: Bloodstream Infections (BSI) Due to CRE|Hospital-Acquired Bacterial Pneumonia (HABP) Due to CRE|Ventilator-Associated Bacterial Pneumonia (VABP) Due to CRE|Complicated Urinary Tract Infection (cUTI) Due to CRE|Acute Pyelonephritis (AP) Due to CRE
Interventions: DRUG: plazomicin|DRUG: colistin|DRUG: meropenem|DRUG: tigecycline|DRUG: antibiotic of Investigator's choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intra-abdominal Pressure on Peritoneal Perfusion During Laparoscopic Colorectal Surgery
Status: COMPLETED
Conditions: Laparoscopic Surgery|Pneumoperitoneum
Interventions: OTHER: Intra-abdominal pressure during laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sprifermin (AS902330) in Cartilage Injury Repair (CIR)
Status: TERMINATED
Conditions: Isolated Cartilage Injury of the Knee
Interventions: DRUG: Sprifermin (AS902330) 10 mcg|DRUG: Sprifermin (AS902330) 30 mcg|DRUG: Sprifermin (AS902330) 100 mcg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of PMG1015
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: PMG1015 Dose 1|DRUG: PMG1015 Dose 2|DRUG: PMG1015 Dose 3|DRUG: PMG1015 Dose 4|DRUG: PMG1015 Dose 5|DRUG: PMG1015 Dose 6|DRUG: Placebo|DRUG: PMG1015 Dose 7
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PVP Compared to TURP for the Treatment of Benign Hyperplasia of the Prostate
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DEVICE: GreenLight HPS (TM)laser system [Photoselective Vaporization of the prostate (PVP)]|PROCEDURE: Transurethral resection of the prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Necitumumab and Trastuzumab in Combination With Osimertinib for the Treatment of Refractory Epidermal Growth Factor Receptor (EGFR)-Mutated Stage IV Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Lung Non-Small Cell Carcinoma|Refractory Lung Non-Small Cell Carcinoma|Stage IV Lung Cancer American Joint Committee on Cancer (AJCC) v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: BIOLOGICAL: Necitumumab|DRUG: Osimertinib|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|BIOLOGICAL: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Risedronate - Parathyroid Hormone Trial in Male Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Risedronate|DRUG: Teriparatide|DRUG: Placebo Teriparatide|DRUG: placebo Risedronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RESTORES Trial: RESToration Of Rehabilitative Function With Epidural Spinal Stimulation
Status: RECRUITING
Conditions: Chronic Spinal Cord Injury
Interventions: DEVICE: RESToration Of Rehabilitative function with Epidural spinal Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Preference for Everolimus in Combination With Exemestane or Capecitabine in Combination With Bevacizumab
Status: COMPLETED
Conditions: Breast Cancer Recurrent|HER2/Neu-negative Carcinoma of Breast|Hormone Receptor Positive Malignant Neoplasm of Breast
Interventions: DRUG: Bevacizumab|DRUG: Capecitabine|DRUG: Everolimus|DRUG: Exemestane|OTHER: Patient questionaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Airway Pressure Release Ventilation as a Preventative Strategy
Status: WITHDRAWN
Conditions: Acute Respiratory Distress Syndrome|Acute Lung Injury|Respiratory Failure|Trauma
Interventions: DEVICE: Airway Pressure Release Ventilation|DEVICE: ARDSnet protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Aripiprazole in the Treatment of Children and Adolescents With Autistic Disorder (AD)
Status: COMPLETED
Conditions: Behavioral Symptoms|Autistic Disorder
Interventions: DRUG: Aripiprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aripiprazole and Effexor XR Drug Interaction Study
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Venlafaxine on Day -4 to day 14, Aripiprazole dosed starting on Day 1: 3 days at 10 mg, 4 days at 1 mg and 7 days at 20 mg.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Biofeedback Vs Electrical Stimulation in Treatment of Fecal Incontinence
Status: COMPLETED
Conditions: Fecal Incontinence|Encopresis|Fecal Soiling
Interventions: DEVICE: Biofeedback|DEVICE: Electrical stimulation|OTHER: Traditional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Axitinib Plus Toripalimab as Second-line Treatment in Hepatobiliary Malignant Tumors
Status: RECRUITING
Conditions: Hepatobiliary Neoplasm|Liver Neoplasm|Biliary Tract Neoplasms
Interventions: DRUG: axitinib plus toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of PRP and XLHA Prepared With RegenMatrix Medical Device To Treat Moderate to Severe Knee Osteoarthritis
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: COMBINATION_PRODUCT: Regen Matrix-PRP-XLHA|DEVICE: Hylan G-F 20|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin, Leucovorin, and Fluorouracil Before and After Radiation Therapy and Surgery in Treating Patients With Rectal Cancer That Can Be Removed by Surgery
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Leucovorin|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin|PROCEDURE: adjuvant therapy|PROCEDURE: neoadjuvant therapy|PROCEDURE: therapeutic conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of GSK3196165 Plus Methotrexate in Subjects With Active Moderate-Severe Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: GSK3196165|DRUG: MTX|DRUG: Folic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Novel Tissue Sealant, Prevention Prolonged Air Leak (PAL) After Lung Resection
Status: COMPLETED
Conditions: Prolonged Air Leak|Lung Resection
Interventions: DEVICE: Hemopatch|PROCEDURE: standard preventive measures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Optimizing(O) RIfapentine-based(RI) Regimen and shortENing(EN) the Treatment of Drug-sensitive Tuberculosis(T)
Status: RECRUITING
Conditions: Tuberculosis, Pulmonary
Interventions: OTHER: Short Regimen with Rifapentine 10mg/kg|COMBINATION_PRODUCT: Standardized Regimen|OTHER: Short Regimen with Rifapentine 15mg/kg|OTHER: Short Regimen with Rifapentine 20mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety, Tolerability, PK of TBAJ-876 in Healthy Adults
Status: COMPLETED
Conditions: Pulmonary Disease|Tuberculosis, Pulmonary|Tuberculosis|Multi Drug Resistant Tuberculosis|Drug Sensitive Tuberculosis|Drug-resistant Tuberculosis|Mycobacterium Tuberculosis Infection
Interventions: DRUG: TBAJ-876 10mg|DRUG: TBAJ-876 25mg|DRUG: TBAJ-876 50mg|DRUG: TBAJ-876 100mg|DRUG: TBAJ-876 200mg|DRUG: TBAJ-876 400mg|DRUG: TBAJ-876 Dose XXXmg for Food cohort|DRUG: TBAJ-876 XXXmg for Part 2|DRUG: Matching Placebo for TBAJ-876 tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Family Caregiver Role in Decreasing Delirium in Older Patients With Fractured Femur Using HELP Principles.
Status: RECRUITING
Conditions: Delirium|Femoral Fracture
Interventions: OTHER: Family caregiver application of HELP principles
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cross-linked Volume-stable Collagen Matrix Versus Connective Tissue Graft at Implant Site.
Status: ACTIVE_NOT_RECRUITING
Conditions: Edentulous Alveolar Ridge Atrophy|Soft Tissue Augmentation at Dental Implants
Interventions: DEVICE: VCMX|PROCEDURE: CTG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: D-CARE - The Dementia Care Study: A Pragmatic Clinical Trial of Health System-Based Versus Community-Based Dementia Care
Status: COMPLETED
Conditions: Dementia
Interventions: OTHER: Health System-based Dementia Care|OTHER: Community-based Dementia Care|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Evaluation Of Two Daily Disposable Contact Lenses And A Monthly Replacement Lens
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: narafilcon B contact lens|DEVICE: nelfilcon A contact lens|DEVICE: lotrafilcon B contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Myofascial Release on Pain, Disability and Electromyography of Erector Spinae in Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain|Disability|Motor Activity|Range of Motion
Interventions: OTHER: myofascial treatment|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Follow-up Study for Patients Previously Treated With a Juno CAR T-Cell Product
Status: TERMINATED
Conditions: Non Hodgkin Lymphoma|Multiple Myeloma|Chronic Lymphocytic Leukemia|Diffuse Large B Cell Lymphoma|Mantle Cell Lymphoma|Follicular Lymphoma
Interventions: GENETIC: JCAR017|GENETIC: JCARH125
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optic Nerve Sheath Diameter in Pediatric Patients
Status: UNKNOWN
Conditions: Optic Nerve Sheath Neoplasm|Intracranial Pressure Increase|Intubation Complication|Airway Complication of Anesthesia
Interventions: DIAGNOSTIC_TEST: Optic nerve sheath diameter measurement with linear ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of the ARTH-e Application on Adherence to Physical Exercises in Patients Suffering From KOA: RCT
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: OTHER: Application ARTH-e
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Metabolism and Pharmacokinetics of [14C] BEA 2180 BR Administered Orally Compared to [14C] BEA 2180 BR Administered Intravenously in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BEA 2180 BR oral|DRUG: BEA 2180 BR infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of QAW039 in Non-atopic Asthmatic Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: QAW039|DRUG: Placebo QAW039|DRUG: Fluticasone 250 mcg|DRUG: Fluticasone 100 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Bupropion Extended-Released 150 mg Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Abrika Bupropion 150 mg Extended-Released Tablet|DRUG: Wellbutrin SR® 150 mg Extended-Release Tablet, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of N-Acetylcysteine Efficacy to Reduce the Craving and to Prolong Abstinence Time of Coca Paste
Status: COMPLETED
Conditions: Cocaine-Related Disorders
Interventions: DRUG: N-Acetylcysteine|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metformin in Patients With Unruptured Vertebrobasilar Dissecting Aneurysms (METTLE)
Status: RECRUITING
Conditions: Dissecting Aneurysm of Cerebral Artery
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safe Babies: Parenting Action Plan ( PAP )
Status: RECRUITING
Conditions: Parenting|Motivational Interviewing|Maltreatment/Abuse
Interventions: BEHAVIORAL: Parenting Action Plan|BEHAVIORAL: Safe Kids Home Safety Checklist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Retarded Phosphatidylcholine Versus Mesalazin in Remission of Ulcerative Colitis.
Status: WITHDRAWN
Conditions: Ulcerative Colitis
Interventions: DRUG: retarded release phosphatidylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The Novel Electrolyzed Water Spray Treatment Mild Senile Groin Eczema, Neurodermatitis and Psoriasis
Status: COMPLETED
Conditions: Groin Infection|Neurodermatitis|Psoriasis|Eczema
Interventions: DEVICE: The novel electrolyzed water spray
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Intervention for Skill Acquisition Support in Autism Spectrum Disorder (ASD)
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: Floreo VR Building Social Connections|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Cabazitaxel in Refractory Metastatic Gastric or Gastroesophageal Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Adenocarcinoma|Gastroesophageal Adenocarcinoma|Distal Esophageal Adenocarcinoma
Interventions: DRUG: Cabazitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplementation of Galatonol 300 mg / Striatin 30 mg in Postpartum Lactating Mothers
Status: NOT_YET_RECRUITING
Conditions: Lactation Induced
Interventions: DRUG: Galatonol 300 mg/Striatin 30 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Two Different Single Doses of Prednisolone on Endodontic Inter-appointment Pain
Status: UNKNOWN
Conditions: Endodontics|Pain
Interventions: DRUG: Prednisolone|DRUG: lactose in capsules gelatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect on Pre-operative Anxiety of a Personalized Three-dimensional Kidney Model Prior to Nephron-sparing Surgery for Renal Tumor.
Status: WITHDRAWN
Conditions: Kidney Neoplasms|Carcinoma, Renal Cell
Interventions: OTHER: Anxiety, renal anatomy and surgery questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cell Phone Technology Targeting ART and Naltrexone Adherence and Alcohol Use
Status: COMPLETED
Conditions: HIV Infections|Alcohol Dependence
Interventions: OTHER: Informational group|BEHAVIORAL: Text Messaging CBT (TXT-CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Managing Anxiety From Cancer (MAC): Testing an Intervention for Anxiety in Older Adults With Cancer and Their Caregivers
Status: ACTIVE_NOT_RECRUITING
Conditions: Anxiety|Depression|Quality of Life
Interventions: BEHAVIORAL: Managing Anxiety from Cancer (MAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Physiology to Evaluate Procedural Result After PCI CTO
Status: RECRUITING
Conditions: Percutaneous Coronary Revascularisation|Complex Coronary Lesion
Interventions: DIAGNOSTIC_TEST: post-PCI Pd/Pa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety Study of Booster Vaccine With the COVID-19 Vaccine (Vero Cell), Inactivated, Omicron Strain
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: COVID-19 Vaccine (Vero Cell), Inactivated, Omicron Strain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Antibacterial Effect of Paradontax Toothpaste
Status: COMPLETED
Conditions: Plaque Induced Gingivitis|Plaque, Dental
Interventions: OTHER: Toothpaste; Paradontax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cataract Surgery: Femto LDV Z8 Versus Conventional
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Femto LDV Z8|DEVICE: Manual capsulorhexis&lens fragmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a Scale of Well-being at Work
Status: COMPLETED
Conditions: Adjustment Disorder
Interventions: OTHER: filling of Serenat at baseline (T1)|OTHER: Serenat at baseline T1 and 3 others questionnaires|OTHER: filling of Serenat, HADS, STAY-Y and BDI at baseline T1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Evaluation of a Single Vaccination With One of Three Ascending Dose Levels of a 4-Antigen Staphylococcus Aureus Vaccine (SA4Ag) in Healthy Adults Aged 18 to <65 Years
Status: COMPLETED
Conditions: Staphylococcal Infections
Interventions: BIOLOGICAL: SA4Ag vaccine low dose|PROCEDURE: Blood draw|PROCEDURE: Colonization swab sample|BIOLOGICAL: SA4Ag vaccine mid dose|PROCEDURE: Blood sample|PROCEDURE: Colonization swab sample|BIOLOGICAL: SA4Ag vaccine high dose|PROCEDURE: Blood draw|PROCEDURE: Colonization swab sample|BIOLOGICAL: Placebo|PROCEDURE: Blood draw|PROCEDURE: Colonization swab sample
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Penehyclidine and Postoperative Nausea and Vomiting After Bimaxillary Surgery
Status: COMPLETED
Conditions: Penehyclidine|Postoperative Nausea and Vomiting|Bimaxillar Surgery
Interventions: DRUG: Penehyclidine hydrochloride|OTHER: No penehyclidine hydrochloride
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Amphetamine-Enhanced Stroke Recovery
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Dextroamphetamine|OTHER: Physical Therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early-onset Alzheimer's Disease Phenotypes: Neuropsychology and Neural Networks
Status: UNKNOWN
Conditions: Alzheimer Disease, Early Onset|Alzheimer Disease|Alzheimer Disease, Late Onset|Dementia, Alzheimer Type|Logopenic Progressive Aphasia|Primary Progressive Aphasia|Visuospatial/Perceptual Abilities|Posterior Cortical Atrophy|Executive Dysfunction|Corticobasal Degeneration|Ideomotor Apraxia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study of Adding Raltegravir (MK-0518) to Antiretroviral Therapy in Patients With Low Level Viremia
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Raltegravir (MK-0518)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Silane Coupling on the Clinical Performance of Repaired Composite
Status: ACTIVE_NOT_RECRUITING
Conditions: Defective Composite Restorations
Interventions: PROCEDURE: composite restoration repair by traditional acid etch treatment procedure and adhesive.|PROCEDURE: Composite restoration repair by acid etching, silane solution application, and then adhesive.|PROCEDURE: Composite restoration repair by sandblasting first, then acid etching, silane solution application, and then adhesive.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Reparative Therapy in Ischemic Stroke COMplex Repair in Ischemic Stroke-Arm
Status: UNKNOWN
Conditions: Ischemic Stroke
Interventions: DRUG: Cerebrolysin infusion|OTHER: Placebo infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Early Swallowing and Speech Intervention for Head and Neck Cancer Patients Treated SURGically
Status: RECRUITING
Conditions: Dysphagia|Head and Neck Cancer
Interventions: BEHAVIORAL: ESSI-SURG|BEHAVIORAL: Standard-of-Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION