pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Multidisciplinary Health Educational Program Based on Centered People Care Model in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: OTHER: Education program based on 10 monthly lectures|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HEART to HAART: Smartphone Intervention to Improve HAART Adherence for Drug Users
Status: COMPLETED
Conditions: HIV|Drug Use Disorders
Interventions: BEHAVIORAL: HEART to HAART|BEHAVIORAL: adherence counseling with the addition of smartphone control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Buccal Misoprostol During Cesarean Section for Preventing Postpartum Hemorrhage
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Misoprostol|DRUG: Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Myofacial Release Technique and Sciatic Nerve Slider Technique in Sciatica
Status: RECRUITING
Conditions: Sciatic Neuropathy|Sciatica|Range of Motion
Interventions: OTHER: Myofacial release technique and sciatic nerve slider technique|OTHER: Myofacial release technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of HEC83518 Tablets
Status: UNKNOWN
Conditions: Insomnia
Interventions: OTHER: Food|DRUG: HEC83518|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Shock Wave Therapy for Sural Myofascial Pain Associated to Chronic Heel Pain
Status: COMPLETED
Conditions: Tendinopathy
Interventions: OTHER: Shock wave therapy on plantar fascia extended to the gastrocnemius-soleus trigger points|OTHER: Shock wave therapy on plantar fascia only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adipose-derived Mesenchymal Stem Cells in Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis|Hip Osteoarthritis|Glenohumeral Osteoarthritis|Osteoarthritis
Interventions: BIOLOGICAL: Intra-articular injection of ADMSC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Motor Imagery and Action Observation Training on Neck Reposition Sense in Patients With Chronic Neck Pain
Status: UNKNOWN
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Action Observation|BEHAVIORAL: Motor Imagery|BEHAVIORAL: Placebo Action Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukaemia
Interventions: DRUG: VP16|RADIATION: TBI|DRUG: Thiotepa|DRUG: Treosulfan|DRUG: Fludarabine|DRUG: Busulfan|DRUG: ATG Thymoglobulin|DRUG: Cyclophosphamide|DRUG: Grafalon
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CEST- Glucose Enhanced MRI for Metastatic Brain Tumours
Status: TERMINATED
Conditions: Brain Neoplasms, Malignant|Metastasis
Interventions: PROCEDURE: Magnetic resonance imaging|DRUG: Gadovist (Gadobutrol)|DRUG: 50% dextrose solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Laparoscopic Cholecystectomy in Children. Risk Factors for Conversion. A Prospective Study .
Status: NOT_YET_RECRUITING
Conditions: Laparoscopic Cholecystectomy in Children
Interventions: PROCEDURE: laparscopic Cholecystectomy in children
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacodynamics and Safety Study of DSP-9632P in Patients With Levodopa-Induced Dyskinesia in Parkinson's Disease
Status: COMPLETED
Conditions: Levodopa-induced Dyskinesia|Parkinson's Disease
Interventions: DRUG: DSP-9632P 27.5 mg|DRUG: DSP-9632P 82.5 mg|DRUG: Placebo|DRUG: DSP-9632P 55.0 mg|DRUG: Levodopa formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Simvastatin Gel With Perforated Resorbable Membranes in Treatment of Intrabony Defects in Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Simvastatin|OTHER: EDTA|DEVICE: Occlusive membrane|DEVICE: Modified perforated membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Distal Radius Fractures in Children Younger Than 11 Years Old.
Status: COMPLETED
Conditions: Bone Fractures|Radius Fractures|Closed Fractures
Interventions: PROCEDURE: Partial reduction with overriding position|PROCEDURE: Closed anatomic reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromodulatory Treatments for Pain Management in TBI
Status: COMPLETED
Conditions: Chronic Pain|Traumatic Brain Injury|Posttraumatic Stress Disorder
Interventions: DEVICE: Mindfulness|DEVICE: Neurofeedback|DEVICE: Relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of StemEx®, to Treat Subjects With High Risk Hematologic Malignancies, Following Myeloablative Therapy
Status: COMPLETED
Conditions: Hematologic Malignancies|Acute Myeloid Leukemia|Lymphoid Leukemia|Chronic Myeloid Leukemia|Hodgkin's Disease|Non-Hodgkin's Lymphoma|Myelodysplastic Syndromes
Interventions: DRUG: StemEx®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Dual Targeted CD19/BCMA FASTCART GC012F in Relapsed/ Refractory Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: GC012F injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Prophylactic Glycerin Suppositories for Feeding Intolerance in Very Low Birth Weight Preterm Infants: a Randomized Trial
Status: TERMINATED
Conditions: Infant, Very Low Birth Weight
Interventions: DRUG: Glycerin suppositories
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized Open-Label Study of INCB047986 in Subjects With Primary Myelodysplastic Syndrome (MDS)
Status: TERMINATED
Conditions: MDS (Myelodysplastic Syndrome)
Interventions: DRUG: INCB047986
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an Intervention With EVOO and Physical Activity in Patients With Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Lupus Erythematosus, Systemic
Interventions: DIETARY_SUPPLEMENT: Extra Virgin Olive Oil (EVOO)|BEHAVIORAL: Physical Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Study of ZetaFuse™ Bone Graft for the Treatment of Cervical Degenerative Disc Disease
Status: RECRUITING
Conditions: Radiculopathy, Cervical|Myelopathy Cervical|Neurological Abnormality|Disc Disease|Disc Degeneration
Interventions: DEVICE: Cervical Fusion (ZetaFuse™ Bone Graft)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Assessing the Effectiveness of a Pharmacist-delivered Smoking Cessation Program in the State of Qatar
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Pharmacist delivered smoking cessation program|OTHER: Control arm (i.e: regular care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Remifentanil Compared to Lidocaine on the Incidence of Coughing During Emergence of Anesthesia
Status: COMPLETED
Conditions: Cough|Anesthesia|Extubation
Interventions: DRUG: Remifentanil|DRUG: Remifentanil|DRUG: lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating Gefitinib (IRESSA®) in Subjects With Solid Malignancies That Are Locally Advanced, Recurrent or Metastatic
Status: COMPLETED
Conditions: Tumors
Interventions: DRUG: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DHEA Replacement in Adrenalectomized/Hypoadrenal Patients
Status: COMPLETED
Conditions: Aging|Dehydroepiandosterone Replacement|DHEA Replacement
Interventions: PROCEDURE: DHEA Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Chronic Postconcussive Headache: A Placebo-Controlled Treatment Trial of Prazosin
Status: COMPLETED
Conditions: Posttraumatic Headache|Combat Disorders|Post Concussion Syndrome|Headache|Mild Traumatic Brain Injury|Posttraumatic Migraine
Interventions: DRUG: prazosin hydrochloride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prochlorperazine Versus Acetaminophen, Aspirin, and Caffeine for the Treatment of Acute Migraine
Status: TERMINATED
Conditions: Migraine Headaches
Interventions: DRUG: Aspirin, Acetaminophen, Caffeine pills|DRUG: Prochlorperazine 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety And Tolerability Of PF-06743649 In Gout Subjects.
Status: TERMINATED
Conditions: Gout
Interventions: DRUG: PF-06743649|OTHER: Placebo|DRUG: PF-06743649|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Salivary Gland Hypofunction With Neuro- Electrostimulation
Status: UNKNOWN
Conditions: Xerostomia|Polypharmacy|Sjögren's Syndrome
Interventions: DEVICE: Automatic neuro-electrostimulation by "Saliwell Crown"|DEVICE: Patient-regulated neuro-electrostimulation by "Saliwell Crown"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acupressure Applied to Menopausal Women on Menopausal Symptoms and Quality of Life
Status: COMPLETED
Conditions: Menopausal Symptom|Quality of Life
Interventions: OTHER: Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized Trial to Evaluated the Suppressive Effect of Acyclovir on Rapidly Cleared HSV-2 Reactivation
Status: COMPLETED
Conditions: Genital Herpes
Interventions: DRUG: acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Doses of Vitamin D on Cancer-related Cognitive Impairment in Patients With Gastrointestinal Tumors
Status: UNKNOWN
Conditions: Gastrointestinal Neoplasms|Cognitive Impairment
Interventions: DRUG: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Determination In-vivo KUF for Diacap Pro Hemodialyser
Status: COMPLETED
Conditions: Kidney Failure,Chronic|Renal Insufficiency,Chronic|Kidney Disease, End-Stage|Kidney Insufficiency
Interventions: DEVICE: Diacap Pro High-Flux
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Saquinavir/Ritonavir in Liver-Impaired Patients With HIV Infection.
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Ritonavir|DRUG: saquinavir [Invirase]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NeoAdjuvant Therapy With Trastuzumab-deruxtecan Versus Chemotherapy+Trastuzumab+Pertuzumab in HER2+ Early Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: HER2-positive Early Breast Cancer
Interventions: DRUG: Trastuzumab deruxtecan|DRUG: Standard-of-Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Amcenestrant in Female Hepatic Impaired Participants as Compared to Participants With Normal Hepatic Function
Status: TERMINATED
Conditions: Hepatic Function Abnormal
Interventions: DRUG: amcenestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Glass Carbomer Performance
Status: COMPLETED
Conditions: Dental Caries
Interventions: OTHER: Restoration of cavities using glass carbomer material (GCP Dental)|OTHER: Restoration of cavities using nanocomposite resin (Tokuyama Estelite Posterior)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy and Multimodal Therapy in Treating Sleep Disturbance in Patients With Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm|Sleep Disorder
Interventions: OTHER: Counseling|DRUG: Methylphenidate Hydrochloride|PROCEDURE: Phototherapy|OTHER: Placebo Administration|OTHER: Quality-of-Life Assessment|PROCEDURE: Sham Intervention|DRUG: Therapeutic Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Mirror Neurons Stimulation on Motor Skill Rehabilitation in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Children With Spastic Diplegia, Between the Ages of 2 to 10 Years|Gross Motor Function Classification System (GMFCS) Level I,II and III
Interventions: PROCEDURE: The mirror neurons stimulation based VCD program|PROCEDURE: The conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Mobile Communication on Congenital Ectopia Lentis Follow-up Adherence
Status: RECRUITING
Conditions: Ectopia Lentis
Interventions: OTHER: smartphone application service and phone reminder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effectiveness of Using Jiu-Jitsu for Coping With Medical Violence in Healthcare Workers
Status: COMPLETED
Conditions: Educational Problems|Workplace Violence|Nursing
Interventions: BEHAVIORAL: Hospital Jujutsu Group, HJJ Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Myeloid Mutations Register in R/R CML
Status: UNKNOWN
Conditions: Chronic Myeloid Leukaemia Recurrent|Chronic Myeloid Leukemia, in Relapse
Interventions: DIAGNOSTIC_TEST: Myeloid mutations measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Remifentanil Target Controlled Infusion Versus Standard of Care for Conscious Sedation During EBUS-TBNA
Status: COMPLETED
Conditions: Lung Cancer|Lung; Node|Sedation Complication|Endoscopy
Interventions: DRUG: Remifentanil TCI|DRUG: Midazolam injection|DRUG: Fentanyl|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Patient's Pretreatment Expectations About Post-Lyme Symptoms
Status: RECRUITING
Conditions: Erythema Migrans
Interventions: DRUG: Antibiotics (preferentially oral doxycycline 100 mg bid)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness and Tolerability of Phentermine in Patients Under Bariatric Surgery
Status: COMPLETED
Conditions: Obesity|Morbid Obesity|Bariatric Surgery|Non-alcoholic Fatty Liver|Weight Loss
Interventions: DRUG: Phentermine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biliary or Digestive Protection by Room Air Interposition for Thermal Ablation of Central Hepatic Tumors
Status: COMPLETED
Conditions: Radiology, Interventional|Liver Neoplasm|Carcinoma, Hepatocellular (RENI)|Neoplasm Metastasis|Ablation Techniques|Radiofrequency Ablation|Microwaves
Interventions: PROCEDURE: Thermal Ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Examine the Effects of Esomeprazole on the Pharmacokinetics of Orally Administered Lapatinib in Subjects With Metastatic ErbB2 Positive Breast Cancer
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: lapatinib|DRUG: lapatinib plus esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing and Calibration of Non-Invasive Optical Imaging Technology for Functional Brain Imaging
Status: SUSPENDED
Conditions: Cognition
Interventions: BEHAVIORAL: Behavioral measures|DEVICE: fNIRS Devices &amp; Application|OTHER: Physiological measures
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Perioperative Multimodal Analgesia Protocol for Supratentorial Craniotomy
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain|Analgesia|Supratentorial Brain Tumor
Interventions: DRUG: Dexmedetomidine|DRUG: Normal saline|OTHER: Local analgesic techniques|OTHER: no Local analgesic techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neural Mechanisms of Music Intervention Chronic Arm Hemiparesis Following Stroke: A Single Case Series EEG Study
Status: RECRUITING
Conditions: Stroke|Hemiparesis|Home-based
Interventions: BEHAVIORAL: Therapeutic Instrumental Music Performance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transcranial Direct Current Stimulation, Improve Functional Motor Recovery, Affected Arm
Status: TERMINATED
Conditions: Brain Infarction|Brain Ischemia
Interventions: DEVICE: t DC stimulation|DEVICE: tDCStimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of T89 in the Prevention and Treatment of Adults With Acute Mountain Sickness (AMS)
Status: COMPLETED
Conditions: Acute Mountain Sickness (AMS)
Interventions: DRUG: T89 capsule|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Video Education on Daily Life Quality and Wound Care in Total Hip Arthroplasty Patients
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Hip
Interventions: OTHER: GROUP GIVEN VIDEO TRAINING
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase II Randomized, Double-Blind, Two-Period Cross-Over Study to Evaluate the Pharmacokinetics, Safety and Tolerability of a Liquid Formulation of Palizvizumab (MEDI-493, Synagis)
Status: COMPLETED
Conditions: -Unhealthy Children With a History of Prematurity
Interventions: DRUG: MEDI-493
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Sulfasalazine in Treating Painful Neuropathy
Status: TERMINATED
Conditions: Painful Neuropathy
Interventions: DRUG: Sulfasalazine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Utility of Commercially Available Sleep Trackers for Physician-Patient Communication
Status: UNKNOWN
Conditions: Insomnia
Interventions: BEHAVIORAL: SleepLife Application w/FitBit|BEHAVIORAL: FitBit w/Minimal to No SleepLife App.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ocriplasmin for Vitreomacular Traction/Symptomatic Vitreomacular Adhesion
Status: COMPLETED
Conditions: Vitreomacular Traction|Vitreomacular Adhesion
Interventions: DRUG: Ocriplasmin 0.125 mg in a 0.1 mL volume
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Utility of Postpartum Antibiotics in Chorioamnionitis
Status: TERMINATED
Conditions: The Primary Outcome of This Study Will be the Rate of Endometritis
Interventions: DRUG: Postpartum Antibiotics|DRUG: No postpartum antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin Injection in Epicardial Fat Pads To Treat Atrial Fibrillation After Cardiac Surgery
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation|Indications for CABG
Interventions: BIOLOGICAL: botulinum toxin injection|BIOLOGICAL: 0.9% normal saline injection|DEVICE: Implantable loop recorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacodynamics Pre-surgical Study of LEE011 in Early Breast Cancer Patients (MONALEESA-1)
Status: TERMINATED
Conditions: Early Breast Cancer
Interventions: DRUG: LEE011 (ribociclib)|DRUG: letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Topical Antioxidants in Dry Eye Disease and Diabetic Retinopathy
Status: UNKNOWN
Conditions: Dry Eye Syndromes|Diabetic Retinopathy|Oxidative Stress|Tear Film Deficiency
Interventions: DRUG: VisuXL®|DRUG: Lagricel PF®|DRUG: Humylub PF®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recombinant Streptokinase Versus Urokinase in Pulmonary Embolism in China (RESUPEC)
Status: COMPLETED
Conditions: Pulmonary Embolism|Pulmonary Thromboembolism
Interventions: DRUG: Recombinant Streptokinase|DRUG: Urokinase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 15-Day Repeated-Dose Study With SB-649868 And Its Interaction With CYP3A4 Isoenzyme In Healthy Male Subjects.
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: DRUG: SB-649868|DRUG: Placebo|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of Analgesic Effect and Postoperative Recovery of SAPB Combined With ESPB and TPB After Thoracoscopic Surgery
Status: UNKNOWN
Conditions: Thoracoscopic Surgery|Nerve Block
Interventions: PROCEDURE: erector spinal plane combined with serratus anterior plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of the Safety, Tolerability and Pharmacokinetics of HMPL-523
Status: COMPLETED
Conditions: Rheumatoid Arthritis (RA)
Interventions: DRUG: HMPL-523|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cholestasis Prevention: Efficacy of IV Fish Oil
Status: COMPLETED
Conditions: Cholestasis|Parenteral Nutrition
Interventions: DRUG: Omegaven|DRUG: Intralipid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Onercept in the Treatment and Re-Treatment of Subjects With Moderate to Severe Plaque Psoriasis
Status: TERMINATED
Conditions: Arthritis, Psoriatic
Interventions: DRUG: Onercept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ovarian Tissue Cryopreservation and Subsequent Auto-Transplantation for Female Cancer Patients
Status: RECRUITING
Conditions: Neoplasms
Interventions: PROCEDURE: Ovarian tissue freezing and subsequent auto-transplantation after thawing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acute Oral Ketones or Carbohydrate Supplement Modify Heart Function in Heart Failure?
Status: NOT_YET_RECRUITING
Conditions: Heart Failure
Interventions: DIETARY_SUPPLEMENT: exogenous ketone salt supplement|DIETARY_SUPPLEMENT: exogenous carbohydrate supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Exploratory Study on the Therapeutic Effect Prediction Model of Advanced BTC Immunotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Biliary Tract Cancer|Immune Checkpoint Inhibitor|Predictive Cancer Model
Interventions: DRUG: Immune Checkpoint Inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Concomitant Milrinone and Esmolol Treatment in Patients With Acute Myocardial Infarction
Status: WITHDRAWN
Conditions: Myocardial Reperfusion Injury
Interventions: DRUG: Milrinone|DRUG: Esmolol|DRUG: Saline Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Investigation Evaluating Wound Closure With OptiPulse™ Versus SOC in the Treatment of Non-Healing DFU's
Status: RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: OptiPulse™|DEVICE: Standard of Care offloading device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Flurbiprofen Spray for Mucosal Graft Harvesting at the Palatal Area
Status: COMPLETED
Conditions: Surgery, Oral
Interventions: DRUG: Flurbiprofen|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interrupting Sitting Time During Postprandial State
Status: COMPLETED
Conditions: Sedentary Behavior
Interventions: BEHAVIORAL: 3-min Exercise Per 30 Min|BEHAVIORAL: 3-min Exercise Per 15 Min
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Evaluation Study of BAT5906 and Lucentis® in Patients With Macular Degeneration
Status: ACTIVE_NOT_RECRUITING
Conditions: Neovascular (Wet) Age-related Macular Degeneration
Interventions: DRUG: BAT5906 injection|DRUG: Lucentis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Metformin on Patients With Osteoarthritis
Status: RECRUITING
Conditions: Osteoarthritis
Interventions: DRUG: Metformin hydrochloride sustained release tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BVD-523 Plus Nab-paclitaxel and Gemcitabine in Patients With Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer|Cancer of Pancreas|Cancer of the Pancreas|Pancreas Cancer
Interventions: DRUG: BVD-523|DRUG: Nab-paclitaxel|DRUG: Gemcitabine|PROCEDURE: Tumor biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of Pit Crew Resuscitation Model on the Training of Advanced Life Support: a Randomized Controlled Study
Status: COMPLETED
Conditions: Advanced Cardiac Life Support
Interventions: OTHER: The pit crew model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Advanced Cognitive Stimulation Therapy Hong Kong (ACST-HK)
Status: UNKNOWN
Conditions: Dementia|Dementia, Vascular|Dementia, Mixed|Dementia With Lewy Bodies|Dementia Frontal|Dementia Severe|Dementia Moderate|Dementia of Alzheimer Type
Interventions: OTHER: Advanced Cognitive Stimulation Therapy Hong Kong
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clopidogrel Reloading in Patients With NSTEACS Undergoing Percutaneous Coronary Intervention on Chronic Clopidogrel Therapy
Status: UNKNOWN
Conditions: Acute Coronary Syndrome|Myocardial Infarction
Interventions: DRUG: Clopidogrel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Immune Profile Selection By Fraction of ctDNA in Patients With Advanced NSCLC Treated With Immunotherapy
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Objective Testing of Tear Film Stability
Status: COMPLETED
Conditions: Contact Lens Solutions
Interventions: DEVICE: Opti-Free® RepleniSH® MPDS|DEVICE: ReNu MultiPlus®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Cross-sectional Study of Lipoprotein(a) Levels in Patients With Documented History of Atherosclerotic Cardiovascular Disease (ASCVD)
Status: COMPLETED
Conditions: Atherosclerotic Cardiovascular Disease
Interventions: OTHER: Lp(a) Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: GW873140 In Combination With Combivir In HIV Infected Subjects
Status: TERMINATED
Conditions: Infection, Human Immunodeficiency Virus I|HIV Infection
Interventions: DRUG: GW873140|DRUG: Combivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ETOS: Minimal Hepatic Encephalopathy in Childhood and Young Adult: epidemiOlogical Study and Pilot Interventional Study
Status: UNKNOWN
Conditions: Hepatic Encephalopathy
Interventions: DIETARY_SUPPLEMENT: probiotic VSL#3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Insulin Detemir for the Treatment of Insulin Dependent Type 1 or Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin detemir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Antibiotic Therapy in Severe Alcoholic Hepatitis Treated With Prednisolone
Status: COMPLETED
Conditions: Alcoholic Hepatitis|Alcoholic Liver Disease
Interventions: DRUG: Amoxicillin|DRUG: Placebo|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation Among Patients Infected by HIV 1 in Virological Failure Owing to Lack of Compliance, of the Benefit in Terms of Compliance of an Optimised Antiretroviral Treatment With Enfuvirtide (Fuzeon) Associated With Two Active Molecules
Status: TERMINATED
Conditions: HIV1 Infection|HIV Infections
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Probiotics and Vitamin D Supplementation on Sport Performance in MMA Athletes.
Status: UNKNOWN
Conditions: Gut Microbiome|Sport Performance
Interventions: COMBINATION_PRODUCT: Probiotic and vitamin D|DIETARY_SUPPLEMENT: placebo and vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Displaced Femoral Neck Fracture in Elderly Patient. Should Cement be Used for Hip Hemiarthroplasty ?
Status: COMPLETED
Conditions: Femoral Neck Fractures
Interventions: PROCEDURE: hemiarthroplasty for displaced femoral neck fractures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pola-R2 in Newly Diagnosed Non-fit Elderly DLBCL Patients
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Polatuzumab Vedotin, Rituximab, Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Find Out How Much Mirabegron Gets Into the Body After Dosing With a Tablet Formulation
Status: COMPLETED
Conditions: Pharmacokinetics of Mirabegron|Bioavailability|Healthy Subjects
Interventions: DRUG: mirabegron OCAS|DRUG: mirabegron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of Thermal Outcome and Safety of Nuera Tight RF System
Status: COMPLETED
Conditions: To Verify Tissue Heating and Temperature Stability and Safety Throughout RF Treatment Duration Applied on the Face
Interventions: DEVICE: NuEra Tight RF system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Hot Water Therapy for the Treatment of Menopause-related Hot Flashes
Status: RECRUITING
Conditions: Menopause|Menopause Related Conditions|Menopause Syndrome
Interventions: BEHAVIORAL: Hot water therapy|BEHAVIORAL: Warm water immersion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Omega-3 Phospholipids on Perceptual-cognitive Training
Status: COMPLETED
Conditions: Cognition - Other
Interventions: DIETARY_SUPPLEMENT: Omega-3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Docetaxel and Erlotinib in Treating Patients With Advanced Non-Small Cell Lung Cancer or Other Solid Tumors
Status: COMPLETED
Conditions: Lung Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: docetaxel|DRUG: erlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Difference Histamine Concentration (1, 5 and 10 mg/ml) for Skin Prick Test Positive Control
Status: COMPLETED
Conditions: Immediate Hypersensitivity
Interventions: PROCEDURE: SPT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Efficacy and Safety Study of Reslizumab Subcutaneous in Patients With Oral Corticosteroid Dependent Asthma and Elevated Blood Eosinophils
Status: COMPLETED
Conditions: Asthma|Elevated Blood Eosinophils|Oral Corticosteroid Dependence
Interventions: DRUG: Reslizumab|DRUG: Placebo|DRUG: Non-Oral Corticosteroid (non-OCS) Asthma Medication|DRUG: Oral Corticosteroid (OCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Default Dosing Settings for Opioid Prescriptions to Adolescents and Young Adults After Tonsillectomy
Status: COMPLETED
Conditions: Tonsillectomy
Interventions: BEHAVIORAL: Default setting intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Serial Daily Diaphragm Ultrasounds in Ventilated Patients
Status: COMPLETED
Conditions: Muscle Atrophy or Weakness|Ventilator-associated Lung Injury
Interventions: PROCEDURE: Ventilation- mandatory|PROCEDURE: Ventilation- voluntary mode only|PROCEDURE: Voluntary with preceding mandatory
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ramadan Fasting in Patients With Corticotrope Deficiency Treated Either by Hydrocortisone or by Prednisolone
Status: COMPLETED
Conditions: Corticotropin Deficiency|Fasting
Interventions: DRUG: Hydrocortisone|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Atopic Dermatitis Biomarker Identification Trial in Omalizumab Usage
Status: COMPLETED
Conditions: Atopic Dermatitis|Atopic Eczema
Interventions: DRUG: Omalizumab (Xolair®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: Physical Activity, Motor Competence, Pulmonary Function, and Quality of Life in Children With Severe Spinal Disease
Status: UNKNOWN
Conditions: Scoliosis; Idiopathic, Infantile|Scoliosis; Juvenile|Scoliosis Neuromuscular|Scoliosis in Neurofibromatosis|Scoliosis; Congenital, Postural|Scoliosis in Skeletal Dysplasia|Scoliosis Associated With Other Conditions|Scoliosis; Congenital, Due to Bony Malformation|Scoliosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1 Study to Evaluate Safety and Tolerability of Single and Multiple Ascending Doses of XEN-101
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: XEN-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prostate Capsule Sparing Cystectomy and Nerve-sparing Radical Cystoprostatectomy in Men With Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer|Transitional Cell Carcinoma of the Bladder
Interventions: PROCEDURE: Prostate capsule sparing cystectomy|PROCEDURE: Nerve sparing cystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VIDEO-TRAINING-SESSION ON METERED DOSE INHALER SKILLS AMONG INDIVIDUALS WITH COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: VIDEO-TRAINING-SESSION ABOUT MDI USE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Headache Inducing Effect of NN414 in Migraine Patients
Status: RECRUITING
Conditions: Headache, Migraine
Interventions: DRUG: NN414|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Chemo-free BRCA-targeted Neoadjuvant Strategy
Status: WITHDRAWN
Conditions: TNBC - Triple-Negative Breast Cancer|BRCA1 Mutation|BRCA2 Mutation
Interventions: DRUG: olaparib|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cortical Enhancement of Posture, Movement Planning, and Execution of Upright Reaching Following Stroke
Status: COMPLETED
Conditions: Stroke|Upper Extremity Paresis
Interventions: OTHER: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impacts of the 10 Steps for Healthy Feeding in Infants: a Randomized Field Trial
Status: COMPLETED
Conditions: Anemia|Breast Feeding, Exclusive|Overweight and Obesity
Interventions: BEHAVIORAL: Dietary Advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Improving Stroke Motor Control With Non-invasive Brain Stimulation and Functional Electrical Stimulation
Status: RECRUITING
Conditions: Stroke|Rehabilitation|Hand
Interventions: DEVICE: transcranial direct current stimulation and electrical stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hearing Impairment, Cognitive Therapy and Coping
Status: UNKNOWN
Conditions: Hearing Loss|Tinnitus|Stress, Psychological|Mental Fatigue
Interventions: BEHAVIORAL: 8-session CBTcourse|BEHAVIORAL: 8 session cognitive behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Fluzoparib Plus Irinotecan as Second-line Treatment in Patients With Homologous Recombination Deficiency (HRD) Metastatic Colorectal Cancer.
Status: NOT_YET_RECRUITING
Conditions: Homologous Recombination Deficiency Alterations Metastatic Colorectal Cancer
Interventions: DRUG: Fluzoparib|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Better Sleep in Psychiatric Care - Bipolar
Status: ENROLLING_BY_INVITATION
Conditions: Sleep Problem|Bipolar Disorder
Interventions: BEHAVIORAL: Adjusted group CBT-i for Bipolar disorder|OTHER: Sleep lectures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anakinra to Treat Patients With Neonatal Onset Multisystem Inflammatory Disease
Status: TERMINATED
Conditions: Nervous System Malformations|Arthropathy, Neurogenic|Urticaria|Papilledema
Interventions: DRUG: anakinra
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Homeopathic Drug Proving Trial
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Homeopathic drug C12|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Calcineurin Inhibitor at Patients With Hemoblastosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Myeloblastic Leukemia|Biphenotypic Acute Leukemia|Malignant Lymphoma|Myelodysplastic Syndromes|Juvenile Myelomonocytic Leukemia
Interventions: COMBINATION_PRODUCT: GVHD prevention: post-transplantation cyclophosphamide, abatacept, vedolizumab, calcineurin inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fire Fighter Fatigue Management Program: Operation Healthy Sleep
Status: COMPLETED
Conditions: Shift-Work Sleep Disorder|Insomnia|Restless Leg Syndrome|Obstructive Sleep Apnea|Impaired Driving|Injuries
Interventions: OTHER: Sleep disorders education and screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of XTMAB-16 in Patients With Pulmonary Sarcoidosis
Status: RECRUITING
Conditions: Pulmonary Sarcoidosis
Interventions: DRUG: XTMAB-16 or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT