pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Innovative Technologies in Restoring Gait and Balance Funtions in Ischemic Stroke Patients at the Inpatient Stage
Status: UNKNOWN
Conditions: Ischemic Stroke, Acute
Interventions: DEVICE: technologies of robotic mechanotherapy with FES|DEVICE: biofeedback virtual reality technologies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: StaphVAX Immunogenicity in Orthopedic Implant Patients
Status: COMPLETED
Conditions: Staphylococcal Infections|Joint Prosthesis
Interventions: BIOLOGICAL: S. aureus Type 5 & 8 Capsular Polysaccharide Conjugate|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Docosahexaenoic Acid (DHA) Replacement for Treatment in Spinocerebellar Ataxia 38
Status: COMPLETED
Conditions: SCA38
Interventions: DIETARY_SUPPLEMENT: DHA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Discontinuation of Steroid Treatment in Negative FDG-PET/CT Patients With Idiopathic Retroperitoneal Fibrosis
Status: RECRUITING
Conditions: Idiopathic Retroperitoneal Fibrosis
Interventions: DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EEG Recordings and Analysis in Parkinson's Patients: Towards Adaptive Deep Brain Stimulation by Machine Learning
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: OTHER: electroencephalogram (EEG) of control and parkinsonian subjects during the preparation and execution of movements
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BFR and Muscle Mitochondrial Oxidative Capacity
Status: COMPLETED
Conditions: Mitochondria|Strength|Hypertrophy
Interventions: BEHAVIORAL: Low Load Resistance Exercise|BEHAVIORAL: Low Load Resistance Exercise + BFR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of GLYX-13 on Learning and Memory in Healthy Individuals and Those With Psychiatric Illness
Status: TERMINATED
Conditions: Psychiatric Illness|Healthy
Interventions: DRUG: GLYX-13|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study to Compare the Efficacy and Safety of Gemigliptin and Vildagliptin as Add-on Therapy to Metformin in People With Type 2 Diabetes Inadequately Controlled With Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: GEMIGLIPTIN LS15-0444|DRUG: vildagliptin|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Rosuvastatin and Olmesartan on the Progression of Coronary Atherosclerotic Disease
Status: UNKNOWN
Conditions: Coronary Syndrome
Interventions: DRUG: Rosuvastatin|DRUG: Olmesartan|DRUG: Combination|DRUG: Placebo of Rosuvastatin|DRUG: Placebo of Olmesartan|DRUG: Placebo of Rosuvastatin/Olmesartan(Combination)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Uncontrolled Study of BAY73-4506 in Previously Untreated Patients With Metastatic or Unresectable RCC
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Regorafenib (Stivarga, BAY73-4506)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sub-Vastus Versus Mid-Vastus Arthrotomy for Total Knee Arthroplasty: a Randomized Clinical Trial
Status: COMPLETED
Conditions: Tricompartmental Gonarthrosis
Interventions: PROCEDURE: Sub-Vastus arthrotomy|PROCEDURE: Mid - Vastus arthrotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics Study of Tolvaptan in Pediatric Congestive Heart Failure (CHF) Patients With Volume Overload
Status: COMPLETED
Conditions: Pediatric Congestive Heart Failure (CHF) Patients With Volume Overload
Interventions: DRUG: Tolvaptan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Measure the Effectiveness of an Intervention Package Aiming to Decrease Perinatal Mortality and Increase Institution-based Obstetric Care Among Indigenous Populations in Guatemala
Status: UNKNOWN
Conditions: ¨Maternal Morbidity¨|¨Perinatal Mortality¨
Interventions: OTHER: package of 3 interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The OPUS YOUNG Trial. Early Intervention Versus Treatment as Usual for Adolescents With First-episode Psychosis
Status: RECRUITING
Conditions: Schizophrenia|Schizotypal Disorder|Delusional Disorder|Acute and Transient Psychotic Disorder, Unspecified|Schizoaffective Disorder|Non-Organic Psychosis|Depression Severe|Substance Induced Psychoses
Interventions: BEHAVIORAL: OPUS YOUNG|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: uPAR-PET/MRI in Glioblastoma Multiforme
Status: UNKNOWN
Conditions: Glioblastoma Multiforme
Interventions: DRUG: One injection of 68Ga-NOTA-AE105|DEVICE: PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Femtosecond Laser-assisted Astigmatism Treatment
Status: UNKNOWN
Conditions: Age Related Cataracts|Astigmatism
Interventions: DEVICE: Femtosecond Laser guided Arcuate Keratotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Re-STOP DVT: Reload of High Dose Atorvastatin for Preventing Deep Vein Thrombosis in Statin Users
Status: UNKNOWN
Conditions: Thrombosis|Prevention|Surgery
Interventions: DRUG: High dose Atorvastatin+enoxaparin|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Efficacy of a Mobile Epilepsy Education Application
Status: RECRUITING
Conditions: Epilepsy|Epilepsy in Children|Anxiety|Knowledge, Attitudes, Practice
Interventions: OTHER: Mobile Epilepsy Education Package|OTHER: Standard care consisting of epilepsy education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SPOON: Sustained Program for Improving Nutrition - Colombia
Status: UNKNOWN
Conditions: Exclusive Breast Feeding|Child Obesity|Malnutrition, Child
Interventions: DIETARY_SUPPLEMENT: Micronutrients|BEHAVIORAL: SPOON Group Counseling|BEHAVIORAL: Interpersonal Counseling|DIETARY_SUPPLEMENT: SQ-LNS|BEHAVIORAL: Standard Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Ambrisentan Sotagliflozin and Prevention of Renal Injury; a Randomized Evaluation
Status: NOT_YET_RECRUITING
Conditions: Type 1 Diabetes Mellitus With Diabetic Nephropathy
Interventions: DRUG: Sotagliflozin|DRUG: Ambrisentan|DRUG: Ambrisentan and Sotagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Effectiveness of Antioxidant Supplementation in Tinnitus
Status: COMPLETED
Conditions: Tinnitus
Interventions: DIETARY_SUPPLEMENT: Antioxidants|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability and Practicability of Envarsus Versus Advagraf in Liver Transplant Recipients
Status: ACTIVE_NOT_RECRUITING
Conditions: Prophylaxis Against Liver Transplant Rejection
Interventions: DRUG: Tacrolimus Pill|DRUG: Tacrolimus capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sotatercept on Central Cardiopulmonary Performance and Peripheral Oxygen Transport During Exercise in Pulmonary Arterial Hypertension
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Sotatercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Medical Honey for Wound Treatment in Intensive Care. (MICARéa) Randomized, Controlled, Single-center Pilot Study.
Status: NOT_YET_RECRUITING
Conditions: Wound Heal|Critical Illness
Interventions: DEVICE: medical honey Activon® 25g Tube|DEVICE: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Paroxysmal Nocturnal Haemoglobinuria Patients With rVA576
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions: DRUG: rVA576|OTHER: Standard of care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety and Tolerability of NCX 4251 for the Treatment of Acute Exacerbations of Blepharitis
Status: COMPLETED
Conditions: Blepharitis
Interventions: DRUG: Fluticasone Propionate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 64CuATSM and Hypoxia in Stage IV Non-small Cell Lung Cancer With Carboplatin, Paclitaxel, and Bevacizumab
Status: WITHDRAWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: 64Cu-ATSM PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastroesophageal Reflux Treatment in Scleroderma
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease|Systemic Sclerosis|Scleroderma
Interventions: DRUG: Alginic acid|DRUG: placebo (for domperidone)|DRUG: Domperidone|DRUG: placebo (of alginic acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation for Severe Obsessive Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: PROCEDURE: Deep Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Linking Brain to Behaviour Research in SCI
Status: COMPLETED
Conditions: Cervical Spinal Cord Injury
Interventions: OTHER: ToCUEST featuring a 'variable practice' approach.|OTHER: ToCUEST featuring a 'constant practice' approach.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind, Controlled Study of the Safety and Performance of the NIRx™ Paclitaxel-Coated Conformer Coronary Stent
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: NIRx(TM) Paclitaxel-Coated Conformer Coronary Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Safety Evaluation of Teneligliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Empaglyflozin 25 mg and Metformin
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: Teneligliptin (as Teneligliptin Hydrobromide) 20 Mg Oral Tablet|DRUG: Teneligliptin Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Luveris® (Lutropin Alfa for Injection) in Women With Hypogonadotropic Hypogonadism (Luteinizing Hormone [LH] Less Than [<] 1.2 International Unit Per Liter [IU/L])
Status: TERMINATED
Conditions: Hypogonadotropic Hypogonadism
Interventions: DRUG: Luveris® 75 IU|DRUG: Luveris® 25 IU|DRUG: Placebo|DRUG: Recombinant human follicle stimulating hormone (r-hFSH)|DRUG: Recombinant human chorionic gonadotropin (r-hCG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesia by Single or Dual Acupoints Stimulation After Radical Mastectomy
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: acupoint stimulation|DEVICE: no stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of R935788 Tablets to Treat Rheumatoid Arthritis (Taski-3)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Fostamatinib disodium (R935788)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting Pathways in Polycystic Ovary Syndrome (PCOS) Using Metformin (MET)
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Trial to Evaluate the Safety and Efficacy of Neuromodulation Using High Intensity Focused Ultrasound 'ExAblate 4000 Type 2.1' in Patients With Psychostimulant Use Disorder(PUD)
Status: NOT_YET_RECRUITING
Conditions: Psychostimulant Use Disorder(PUD)
Interventions: DEVICE: ExAblate 4000 Type 2.1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Point-of-care Lung Ultrasound for the Management of Childhood Lower Respiratory Infections
Status: NOT_YET_RECRUITING
Conditions: Lower Respiratory Infection|LRTI|Pneumonia|Bronchiolitis
Interventions: DIAGNOSTIC_TEST: Point-of-care lung ultrasound|DIAGNOSTIC_TEST: Chest X-ray (digital images)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Chitosan as Irrigating Solution for Pulpectomy in Non-Vital Primary Teeth
Status: COMPLETED
Conditions: Pulpal Necrosis
Interventions: PROCEDURE: Sodium hypochlorite irrigating solution|PROCEDURE: one minute NaOCL+Chitosan|PROCEDURE: Three minute NaOCL+Chitosan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chlorhexidine Intracanal Medicament in Periodontal Healing in Concomitant Endo Perio Lesion With Communication
Status: COMPLETED
Conditions: Periodontal Pocket|Tooth,Non Vital
Interventions: PROCEDURE: open flap debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TOT, TVT And Burch Colpo-Suspension for Treatment of Female Mixed Urinary Incontinence
Status: COMPLETED
Conditions: Treatment
Interventions: PROCEDURE: TOT|PROCEDURE: TVT|PROCEDURE: Burch Colposuspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of 50% Nitrous Oxide Inhalation on Pain and Anxiety Induced by Lumbar Puncture: a Double-blind Randomized Controlled Trial
Status: UNKNOWN
Conditions: Lumbar Puncture
Interventions: DRUG: 50:50 mixture of nitrous oxide/oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clonidine to Prevent Delirium After Electroconvulsive Therapy.
Status: RECRUITING
Conditions: Major Depressive Disorder|Catatonia|Bipolar Disorder|Delirium Postseizure
Interventions: DRUG: Clonidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Allogeneic Stem Cell Transplantation in Pediatric Patients With Malignant and Non-malignant High-risk Diseases
Status: TERMINATED
Conditions: Malignant and Non-malignant High Risk Diseases
Interventions: OTHER: Hematopoietic stem cell product from haploidentical or unrelated donor CD3/CD19 depleted with CliniMACS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monitored Anesthesia Care: Dexmedetomidine-Ketamine Versus Dexmedetomidine- Propofol For Chronic Subdural Hematoma
Status: COMPLETED
Conditions: Conscious Sedation
Interventions: DRUG: dexmedetomidine- ketamine|DRUG: dexmedetomidine- propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RECOVER I Impella RECOVER LP/LD 5.0 Support System Safety and Feasibility Study
Status: COMPLETED
Conditions: Cardiac Surgery
Interventions: DEVICE: IMPELLA LP/LD 5.0
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Bromhexine and Hydroxychloroquine for Treatment of COVID-19 Pneumonia
Status: UNKNOWN
Conditions: Covid-19
Interventions: DRUG: Bromhexine Oral Tablet and/or hydroxychloroquine tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sunitinib in Sarcomas of the Central Nervous System
Status: TERMINATED
Conditions: Gliosarcoma|Central Nervous System Sarcoma
Interventions: DRUG: Sunitinib|DEVICE: wGT3x-BT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
Status: RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Lasofoxifene in combination with abemaciclib|DRUG: Fulvestrant in combination with abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Oxycodone/Naloxone Controlled-release Tablets (OXN) Compared to Placebo in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Oxycodone/Naloxone Controlled-release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in People With Overweight or Obesity to Test How Well Different Doses of BI 1820237 Are Tolerated When Given Alone or in Combination With Either Semaglutide or BI 456906
Status: COMPLETED
Conditions: Healthy|Obesity
Interventions: DRUG: BI 1820237|DRUG: semaglutide|DRUG: Placebo|DRUG: BI 456906
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Pilates on Posture and Physical Fitness Parameters in 5-6 Years Old Children
Status: COMPLETED
Conditions: Posture|Physical Fitness
Interventions: OTHER: Pilates exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Plasma Exchange Therapy vs Standard Medical Therapy in Severe Alcoholic Hepatitis With High Discriminant Function
Status: RECRUITING
Conditions: Alcoholic Hepatitis
Interventions: BIOLOGICAL: Plasma Exchange|OTHER: Standard Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Very Early and Rapid Lowering Cholesterol With Evolocumab on Left Ventricular Remodeling in Patients With Anterior STEMI Undergoing Primary PCI
Status: RECRUITING
Conditions: ST Elevation Myocardial Infarction (STEMI)
Interventions: DRUG: Rosuvastatin 20 mg|DRUG: Evolocumab 140 mg/1 ml Subcutaneous Solution [REPATHA]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anaesthetic Depth and Short Term Delirium Post Cardiac Surgery Intervention
Status: NOT_YET_RECRUITING
Conditions: Post-operative Delirium|Anaesthetic Depth
Interventions: DRUG: General anesthesia with propofol or sevoflurane|BEHAVIORAL: CAM-ICU (Confusion Assesment Method ICU) at day 3 post-operative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Preoperative PRRT Versus Surgical Cytoreduction in Metastatic Pancreatic Neuroendocrine Tumors to the Liver
Status: RECRUITING
Conditions: Pancreatic Neuroendocrine Tumor|Pancreas Cancer
Interventions: PROCEDURE: cytoreductive surgery|DRUG: Lutathera - a small molecule used in Peptide Receptor Radionuclide Therapy (PRRT)|PROCEDURE: Peptide receptor radionuclide therapy (PRRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Antioxidant on Endurance Performance in Healthy Men
Status: COMPLETED
Conditions: Exercise Tolerance
Interventions: DIETARY_SUPPLEMENT: Oligomerized litchi fruit extract|DIETARY_SUPPLEMENT: VItamin C + Vitamin E mixture|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First-line Treatment of P53 Mutation With PD-L1 Expression in DLBCL With Anti-PD-1 Mab and R-CHOP
Status: NOT_YET_RECRUITING
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Sintilimab|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endovenous Sildenafil Early Management in Newborns Pulmonary Hypertension
Status: UNKNOWN
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Sildenafil Injectable Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Biodentine Partial Pulpotomy of Pulpally Exposed Primary Molars
Status: WITHDRAWN
Conditions: Pulpotomy|Tooth, Deciduous
Interventions: PROCEDURE: partial pulpotomy with biodentine|PROCEDURE: Formocresol pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation and Computer-based Training for the Traumatic Brain Injury Rehabilitation
Status: UNKNOWN
Conditions: Traumatic Brain Injury
Interventions: DEVICE: anodal tDCS|DEVICE: Computer-assisted training|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of Auricular Acupressure in Treating Estazolam-dependent Insomnia
Status: NOT_YET_RECRUITING
Conditions: Estazolam-dependent Insomnia
Interventions: DRUG: Conventional dosage reduction|PROCEDURE: Auricular acupressure|PROCEDURE: Sham auricular acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Performance of Two Toric Silicone Hydrogel Contact Lenses
Status: COMPLETED
Conditions: Astigmatism
Interventions: DEVICE: fanfilcon A toric lens|DEVICE: senofilcon A toric lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Inhaled Nitric Oxide in Vascular Mechanics and Right Ventricular Function
Status: RECRUITING
Conditions: Collapsed Lung|Hemodynamic Stability
Interventions: PROCEDURE: Alveolar recruitment maneuver|DRUG: Nitric Oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Gene Sequencing in Guiding Treatment Recommendations Patients With Metastatic or Recurrent Solid Tumors
Status: COMPLETED
Conditions: Recurrent Breast Cancer|Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IV Breast Cancer|Stage IVA Colon Cancer|Stage IVA Rectal Cancer|Stage IVB Colon Cancer|Stage IVB Rectal Cancer
Interventions: OTHER: cytology specimen collection procedure|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Thoracic Paravertebral Block in Pain Management After Renal Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Paravertebral blockade (PVB)|DRUG: Sopodorm|DRUG: Propofol WZF|DRUG: Nimbex|DRUG: Fentanyl WZF|DRUG: Sevorane|DEVICE: Intubation|DRUG: Oxynorm|DRUG: Paracetamol Kabi|DRUG: Ketonal|DRUG: Bupivacaine WZF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Effects of Krill Oil and Fish Oil Supplementation on Muscle Function in Older Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Fish oil|DIETARY_SUPPLEMENT: Kril oil|DIETARY_SUPPLEMENT: Vegetable oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Ramdicivir and Baricitinib for the Treatment of Severe COVID 19 Patients
Status: UNKNOWN
Conditions: Covid19|Covid-19 ARDS
Interventions: DRUG: Remdesivir|DRUG: Baricitinib|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Oxazolidinone to Treat Pneumonia
Status: COMPLETED
Conditions: Community-Acquired Pneumonia (CAP)
Interventions: DRUG: Radezolid|DRUG: Radezolid|DRUG: Radezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nitrous Oxide for PTSD
Status: TERMINATED
Conditions: PTSD
Interventions: DRUG: Nitrous Oxide|DRUG: Midazolam|DRUG: Nitrogen|DRUG: Oxygen|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RFD Versus Cervical Medial Branch Blocks in Chronic Degenerative Neck Pain
Status: UNKNOWN
Conditions: Facet Joint Arthritis|Pain|Radiofrequency Denervation
Interventions: PROCEDURE: Radio Frequency Denervation|PROCEDURE: Local Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SU011248 for Platinum-Refractory Urothelial Cancer Evaluation Trial
Status: COMPLETED
Conditions: Urothelial Cancer|Bladder Cancer|Adult
Interventions: DRUG: SU011248|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Prucalopride in Male Subjects With Chronic Constipation.
Status: COMPLETED
Conditions: Male Subjects With Chronic Constipation
Interventions: DRUG: Placebo|DRUG: Prucalopride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Trial of Afatinib (Giotrif) in Treatment-naive (1st Line) or Chemotherapy Pre-treated Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Harboring EGFR Mutation(s)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravascular Lithotripsy and/or Mechanical Debulking for Severely Calcified Coronary Artery Lesions
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Myocardial Infarction
Interventions: DEVICE: Intravascular Lithotripsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Therapy for Patients With Untreated Metastatic Pancreatic Ductal Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Untreated Metastatic Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Nivolumab|DRUG: Albumin-bound paclitaxel|DRUG: Paricalcitol|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heated Saline in Cervical Balloon for Labor Induction, a RCT
Status: RECRUITING
Conditions: Cervical Ripening|Induction of Labor|Unfavorable Cervix|Mechanical Method
Interventions: DEVICE: Warm group|DEVICE: Room temperature group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telmisartan as an Adjunctive Treatment for Metabolic Problems in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Telmisartan|DRUG: Placebo|DRUG: Clozapine|DRUG: Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of Enantone (Leuprorelin) in Central Precocious Puberty (CPP) Among Chinese Participants
Status: COMPLETED
Conditions: Central Precocious Puberty
Interventions: DRUG: Enantone|DRUG: GnRH agonist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Retrospective Chart Review and Historical Comparison of Capmatinib vs. Standard of Care for German Adult Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Harboring METex14 Mutations
Status: COMPLETED
Conditions: Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring METex14 Mutations
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: State-dependent Interoception, Value-based Decision-making, and Introspection
Status: RECRUITING
Conditions: Stress|Pain|Emotions|Craving|Frustration
Interventions: OTHER: Pain|OTHER: Stress|BEHAVIORAL: Craving|BEHAVIORAL: Frustration|BEHAVIORAL: Negative valence emotion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness-Implementation Cluster RCT to Improve Community-dwelling Early Dementia Patients by Music Intervention
Status: COMPLETED
Conditions: Dementia
Interventions: BEHAVIORAL: Music-with-movement|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Second-line Treatment in Advanced Colorectal Cancer With Chemotherapy With Bevacizumab or Cetuximab
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: irinotecan liposome (II)|DRUG: fluorouracil|DRUG: cetuximab|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Oral NRC-2694-A in Combination With Paclitaxel in Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma, Who Progressed on or After Immune Checkpoint Inhibitor Therapy
Status: RECRUITING
Conditions: Carcinoma|Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: NRC-2694-A|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Cyanoacrylate Adhesives to Sutures in the Palate After Connective Tissue Graft
Status: UNKNOWN
Conditions: Wound Closure
Interventions: DEVICE: n-butyl cyanoacrylate and 2-octyl cyanoacrylate|DEVICE: 5-0 Polytetrafluoroethylene (PTFE) suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Implant Component Materials on Peri-implant Soft Tissue Horst Response.
Status: COMPLETED
Conditions: Dental Implants|Soft Tissue Inflammation|Immunohistochemistry|Dental Implants, Single-Tooth|Histology|Dental Implantation
Interventions: DEVICE: Experimental healing abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Mirror Therapy Versus Fine Motor Activities on Hand Function in Chronic Stroke Patients.
Status: COMPLETED
Conditions: Stroke, Ischemic|Acute Pain|Weakness, Muscle
Interventions: OTHER: fine motor activities|OTHER: conventional therapy and mirror therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Pain-treatment Techniques After Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section|Pain Management|Neuropathic Pain
Interventions: PROCEDURE: TAP (transversus abdominis plane block)|PROCEDURE: QL (quadratus lumborum block)|DRUG: Bupivacaine|DEVICE: Needle|DRUG: Paracetamol|DRUG: Metamizol|DRUG: Ketoprofen|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Proprioceptive Exercises Program in Patients With Carpometacarpal Joint Osteoarthritis
Status: COMPLETED
Conditions: Thumb Osteoarthritis
Interventions: OTHER: Proprioception exercises|OTHER: Joint protection program|OTHER: Thumb orthosis|OTHER: Manual distraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Surgical Intervention to Treat Epilepsy
Status: COMPLETED
Conditions: Epilepsy|Epilepsy, Temporal Lobe|Seizures
Interventions: PROCEDURE: anteromesial temporal resection|DRUG: antiepileptic drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Itolizumab in Subjects Hospitalized With COVID-19
Status: WITHDRAWN
Conditions: Coronavirus
Interventions: BIOLOGICAL: EQ001|BIOLOGICAL: EQ001 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-74856665 in Participants With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia
Interventions: DRUG: JNJ-74856665|DRUG: AZA|DRUG: VEN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TreatIng Microalbuminuria Over 24 Weeks in Subjects With or Without Type 2 Diabetes or HYpertension
Status: TERMINATED
Conditions: Albuminuria
Interventions: DRUG: Dapagliflozin 10Mg Tab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Augmentation of Anterior Cruciate Ligament Reconstruction Using Mesenchymal Stem Cells and Collagen Matrix Carrier
Status: RECRUITING
Conditions: ACL Tear
Interventions: PROCEDURE: ACL reconstruction|PROCEDURE: Mesenchymal stem cell implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MCLENA-1: A Clinical Trial for the Assessment of Lenalidomide in Amnestic MCI Patients
Status: RECRUITING
Conditions: Cognitive Impairment, Mild|Cognitive Dysfunction|Amyloid Plaque|Neurodegeneration|Inflammation, Brain
Interventions: DRUG: Lenalidomide 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating The Safety Of Xyntha In Usual Care Settings
Status: TERMINATED
Conditions: Hemophilia A
Interventions: BIOLOGICAL: Moroctocog alfa(AF-CC)|PROCEDURE: Blood draw for laboratory testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Different Strategies to Prevent Propofol Induced Pain During Infusion
Status: UNKNOWN
Conditions: Induction of Total Intravenous General Anesthesia
Interventions: DRUG: kétamine 20mg|DRUG: ephedrine 3mg|DRUG: lidocaine 40mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Bendamustine + Obinutuzumab Induction With Obinutuzumab Maintenance in Untreated Mantle Cell Lymphoma
Status: TERMINATED
Conditions: Mantle Cell Lymphoma|Non-hodgkin Lymphoma|Non Hodgkin Lymphoma
Interventions: DRUG: Bendamustine|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparator Study of Fluticasone Propionate Nasal Spray Verses (vs) Cetirizine in the Treatment of Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial and Seasonal
Interventions: DRUG: FPNS|DRUG: FPNS Placebo|DRUG: Cetirizine|DRUG: Cetirizine Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of ARCT-810 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Ornithine Transcarbamylase Deficiency
Interventions: BIOLOGICAL: ARCT-810|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer
Status: RECRUITING
Conditions: Advanced Solid Tumor|Metastatic Cancer
Interventions: DRUG: AU-007|DRUG: Aldesleukin|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI in Transcatheter Aortic Valve Replacement Patients
Status: RECRUITING
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: Self-expanding valve (Medtronic Evolut FX)|DEVICE: Balloon-expanding valve (Edwards Sapien 3 Ultra)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Feasibility of Functional Electrical Stimulation for The Treatment of Premature Ejaculation
Status: UNKNOWN
Conditions: Premature Ejaculation
Interventions: DEVICE: Functional TENS stimulation|DEVICE: Non-Functional TENS stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Optimizing PrEP Regimens for Pregnant Women in Sub-Saharan Africa (O-PrEP Study) - Stage 1
Status: RECRUITING
Conditions: HIV|Prevention|Pregnancy
Interventions: DRUG: FTC/TDF 200mg/300mg|DRUG: FTC/TDF 300mg/450mg|DRUG: FTC/TDF 400mg/600mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Electrophysiologically Guided PAcing Site Selection Study
Status: COMPLETED
Conditions: Sinus Arrhythmia|Atrial Fibrillation
Interventions: PROCEDURE: IAS pacing - study group|PROCEDURE: IAS pacing control group|PROCEDURE: Pacing RAA study group|PROCEDURE: Pacing RAA control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study of Low Level Laser Therapy for Body Contouring
Status: COMPLETED
Conditions: Body Contouring
Interventions: DEVICE: Erchonia ML Scanner (MLS)|DEVICE: Sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Neuroinflammation in Parkinson's Disease Using 18F-NOS PET/CT
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease|Healthy Volunteer
Interventions: DRUG: [18F]NOS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Myofascial Release and Joint Mobilization Therapy in Non-Specific Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: OTHER: Joint mobilization|OTHER: Myofascial Release|OTHER: Joint mobilization & Myofascial Release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanism of Action of Focal Extracorporeal Shock Waves as a Treatment of Upper Limb Stroke Spasticity: a Pilot Study
Status: RECRUITING
Conditions: Stroke|Hemiparesis|Hemiplegia|Spasticity as Sequela of Stroke|Upper Limb Hypertonia
Interventions: OTHER: Extracorporeal Shockwave Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Study of Efficacy and Safety of Mexidol® in Stroke Therapy (MIR)
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DRUG: Mexidol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Dose-response Effects of High Intensity Functional Training on Metabolic Syndrome Risk Factors
Status: COMPLETED
Conditions: Metabolic Syndrome|Atherogenic Dyslipidemia|Insulin Resistance|Endothelial Dysfunction
Interventions: BEHAVIORAL: HIFT 1x/week|BEHAVIORAL: HIFT 2x/week|BEHAVIORAL: HIFT 3x/week
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label, Randomized Study Evaluating Treatment With Venlafaxine Extended-Release Plus Dialogues Time to Talk Program
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Venlafaxine ER|BEHAVIORAL: Dialogues Time to Talk Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine-Ketamine Infusion in Breast Surgeries
Status: COMPLETED
Conditions: Total Intravenous Anesthesia
Interventions: DRUG: Placebos|DRUG: Dexmedetomidine +Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness and Cost-effectiveness of PelviSense, a Novel Biofeedback Device for Stress Urinary Incontinence in Women
Status: NOT_YET_RECRUITING
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: PelviSense-assisted pelvic floor muscle training group|OTHER: Active comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Kinesiotaping and Manipulation Therapies in Drooling Management Among Children With Oral Dysphagia
Status: UNKNOWN
Conditions: Drooling
Interventions: OTHER: kinesiotaping therapy|OTHER: oral motor manipulation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methodological Validation of Ibuprofen Verses Placebo for Post Operative Pain After Third Molar Extraction Surgery
Status: COMPLETED
Conditions: Dental Pain
Interventions: DRUG: Placebo|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nursing Students' Attitudes Towards Artificial Intelligence and Exam Anxiety Levels
Status: COMPLETED
Conditions: Nurse's Role|Anxiety|Educational Problems
Interventions: BEHAVIORAL: Experimental Group (Educational content; ChatGPT and Google Bard training)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE