pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Wrist-Worn Nerve Stimulator for Remediating Persistent Post-Concussive Symptoms in Adolescents
Status: RECRUITING
Conditions: Concussion, Brain
Interventions: DEVICE: Apollo Neuro
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Preemptive Analgesia On The Comfort Of Patient and Doctor, in Cystoscopy
Status: UNKNOWN
Conditions: Bladder Cancer|Benign Prostate Hyperplasia|Hematuria|Pain|Lower Urinary Tract Symptoms
Interventions: DRUG: Diclofenac Sodium|DEVICE: Cystoscopy|DRUG: Lubricant Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Influence of Residual Astigmatism on Visual Acuity in Patients Undergoing Cataract Surgery With Trifocal Intraocular Lens Implantation
Status: UNKNOWN
Conditions: Cataract After|Astigmatism|IOL|Visual Acuity
Interventions: OTHER: Kind of trifocal IOL
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Monitoring Neuromuscular Blockade the Flexor Hallucis Compared to the Adductor Pollicis
Status: COMPLETED
Conditions: Observation of Neuromuscular Block|Flexor Hallucis|Adductor Pollicis
Interventions: DEVICE: Monitoring Neuromuscular Blockade the Flexor Hallucis|DEVICE: Monitoring Neuromuscular Blockade adductor of the thumb.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Extension Study of Pimavanserin in Adult Subjects With Neuropsychiatric Symptoms Related to Neurodegenerative Disease
Status: COMPLETED
Conditions: Neuropsychiatric Symptoms Related to Neurodegenerative Disease
Interventions: DRUG: Pimavanserin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Arrhythmia and ECG Abnormalities in Patients With COVID-19
Status: COMPLETED
Conditions: Arrhythmia|SARS-CoV-2 Infection
Interventions: DIAGNOSTIC_TEST: ECG data analysis|DRUG: Treatment data collect|BIOLOGICAL: Biological check-up data collect|OTHER: Collection of clinical events of interest
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Semaglutide Effects in Obese Youth With Prediabetes/New Onset Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus|Impaired Glucose Tolerance|Non-Alcoholic Fatty Liver Disease|Obesity, Childhood
Interventions: DRUG: Semaglutide Pen Injector|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postpartum Women's Dexmedetomidine Sedation
Status: COMPLETED
Conditions: Cesarean Section
Interventions: DRUG: Dexmedetomidine 01|DRUG: Dexmetomidine 02
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Shockwave Therapy on Cervical Myofascial Syndrome in Lactating Women
Status: COMPLETED
Conditions: Cervical Myofascial Pain Syndrome
Interventions: DEVICE: Shockwave
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Xience in Coronary arEry Disease aLL-comers After stENTing Using the PRIME Platform (EXCELLENT-PRIME Registry)
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: XIENCE PRIMETM everolimus-eluting coronary stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Nitrate and Cardiovascular Health
Status: COMPLETED
Conditions: no Medications
Interventions: DIETARY_SUPPLEMENT: Dietary nitrate|DIETARY_SUPPLEMENT: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Efficacy and Safety of LXH254 Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: DRUG: LXH254|DRUG: LTT462|DRUG: Trametinib|DRUG: Ribociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analyzing Genetic Factors Involved in Blood Pressure Changes Due to Salt and Potassium Intake (The GenSalt Study)
Status: COMPLETED
Conditions: Blood Pressure
Interventions: BEHAVIORAL: Low Sodium Diet|BEHAVIORAL: High Sodium Diet|DIETARY_SUPPLEMENT: Potassium Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Repetitive Transcranial Magnetic Stimulation in Essential Tremors Patients
Status: COMPLETED
Conditions: Essential Tremor
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation|DEVICE: Sham Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of CD19 Targeted CAR-T Therapy for Refractory Autoimmune Disease
Status: RECRUITING
Conditions: SLE (Systemic Lupus)|Sjogren's Syndrome|Systemic Scleroderma|Dermatomyositis|Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Interventions: BIOLOGICAL: CD19 targeted CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Caudal Epidural Block and Ultrasound Guided Transversus Abdominis Plane Block for Post Operative Analgesia in Children Undergoing Infraumblical Surgeries
Status: UNKNOWN
Conditions: Post Operative Analgesia in Children Undergoing Infraumblical Surgeries
Interventions: DRUG: Caudal Epidural Block using 0.25% plain bupivacaine dose 1 ml / kg and Ultrasound Guided Transversus Abdominis Plane Block using 0.25% plain bupivacaine dose 0.5 ml / kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Palomid 529 a Dual TORC1/2 Inhibitor of the PI3K/Akt/mTOR Pathway for Advanced Neovascular Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: Palomid 529
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ESTIMation of the ABiLity of Prophylactic Central Compartment Neck Dissection to Modify Outcomes in Low-risk Differentiated Thyroid Cancer
Status: RECRUITING
Conditions: Thyroid Cancer
Interventions: PROCEDURE: total thyroidectomy with bilateral prophylactic central compartment (level VI) neck dissection|PROCEDURE: total thyroidectomy alone without neck dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Prevention of Anal Cancer
Status: COMPLETED
Conditions: Human Papillomavirus|Cancer
Interventions: PROCEDURE: Participants asked questions about recent experiences of anal intercourse in the last six months.|PROCEDURE: High Resolution Anoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial to Evaluate the Effect of Nilotinib on the PK/PD of Meformin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Metformin|DRUG: Metformin + Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrated Supported Biopsychosocial Self-Management for Back Related Leg Pain
Status: COMPLETED
Conditions: Low Back Pain|Sciatica|Back Related Leg Pain|Pain, Chronic|Intervertebral Disc Displacement
Interventions: BEHAVIORAL: Supported Biopsychosocial Self-Management (SBSM)|DRUG: Medical Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Oral Probiotics to Reduce Vaginal Group B Streptococcal Colonization in Late Pregnancy
Status: COMPLETED
Conditions: Vaginal Infection|Pregnancy Complications|Neonatal Sepsis|GBS
Interventions: DIETARY_SUPPLEMENT: Astarte® (HSO Health Care GmbH, Vienna, Austria)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Red Cell Lysis Buffer Application Versus Conventional Sample Processing in EUS-FNB
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Diseases
Interventions: PROCEDURE: Red cell lysis buffer (RCLB) application|PROCEDURE: Conventional processing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part II
Status: WITHDRAWN
Conditions: Hypothermia
Interventions: PROCEDURE: Thermoregulation-standard care|PROCEDURE: Thermoregulation with plastic bag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Test the Effects of Tolterodine Tartrate in Patients With Overactive Bladder (0000-107)
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: tolterodine tartrate|DRUG: Comparator: Placebo to tolterodine tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effectiveness of Hypochlorous Acid and Chlorhexidine as a Post-surgical Antimicrobial Agent
Status: COMPLETED
Conditions: Periodontal Diseases|Chronic Periodontitis|Microbial Colonization
Interventions: OTHER: Mouthwash|OTHER: Chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of @neWorld: A Virtual Community for Children With Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Psychosocial Effects of Cancer and Its Treatment|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: PROCEDURE: complementary or alternative medicine procedure|PROCEDURE: management of therapy complications|PROCEDURE: psychosocial assessment and care
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Clinical and Radiographic Evaluation of the Synergistic Effect of Nano Silver Particles and Calcium Hydroxide Versus Triple Antibiotic Paste as Antibacterial Agents for Lesion Sterilization and Tissue Repair (LSTR) in Necrotic Primary Molars
Status: NOT_YET_RECRUITING
Conditions: Root Canal Infection
Interventions: OTHER: Nano silver particles and calcium hydroxide|OTHER: TAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Ranging Study of an Ophthalamic Solution in Patients With Loss of Visual Function Due to Age-Related Nuclear Cataract
Status: UNKNOWN
Conditions: Nuclear Cataract
Interventions: DRUG: LiquiTears|DRUG: C-KAD Ophthalmic Solution|DRUG: C-KAD Ophthalmic Solution|DRUG: C-KAD Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Ovasave, an Autologous Cell Therapy, in Patients With Active Crohn's Disease
Status: TERMINATED
Conditions: Crohn Disease
Interventions: DRUG: Ovasave|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liposomal Bupivacaine Pharmacokinetic Study After Median Sternotomy Incision Infiltration in a Pediatric Cardiac Surgery
Status: TERMINATED
Conditions: Cardiac Conditions
Interventions: DRUG: Bupivacaine liposome
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of BAT8009
Status: RECRUITING
Conditions: Locally Advanced/Metastatic Solid Tumours
Interventions: DRUG: BAT8009 for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eradication Efficacy and Safety of Two Rescue Treatments for Helicobacter Pylori Infection
Status: UNKNOWN
Conditions: H. Pylori Infection
Interventions: DRUG: esomeprazole plus amoxicillin|DRUG: amoxicillin, furazolidone, bismuth potassium citrate , esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib Pharmacodynamic Study of Neoadjuvant Paricalcitol in Resectable Pancreatic Cancer A Phase Ib Pharmacodynamic Study of Neoadjuvant Paricalcitol in Resectable Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: Paricalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amyloidosis Typing Using Mass Spectrometry-based Proteomics: a New Accurate Tool for Difficult Typing
Status: COMPLETED
Conditions: Amyloidosis
Interventions: DIAGNOSTIC_TEST: Amyloidosis typing using mass spectrometry-based proteomics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Image-Guided Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Shoulder, Arm, Hip, or Leg
Status: COMPLETED
Conditions: Lymphedema|Musculoskeletal Complications|Radiation Fibrosis|Radiation Toxicity|Sarcoma
Interventions: DRUG: Chemotherapy|RADIATION: Radiation therapy|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ginkgo Biloba: Antidepressant-Induced Sexual Dysfunction
Status: COMPLETED
Conditions: Hypoactive Sexual Desire Disorder|Sexual Dysfunctions, Psychological
Interventions: DRUG: Ginkgo Biloba|BEHAVIORAL: Sex Therapy (genital focus)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Open Label Study Evaluating JUVÉDERM® VOLBELLA With Lidocaine Treatment for the Correction of Skin Depressions in the Infra-orbital Area
Status: COMPLETED
Conditions: Infra-orbital Skin Depressions
Interventions: DEVICE: VOLBELLA® with lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of 3% LTX-109 for Nasal Decolonisation of Staphylococcus
Status: COMPLETED
Conditions: Nasal Decolonization of Staphylococcus Aureus
Interventions: DRUG: LTX-109 gel, 3% w/w|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating the Long-term Safety and Efficacy of Deferiprone in Patients With Friedreich's Ataxia
Status: COMPLETED
Conditions: Friedreich's Ataxia
Interventions: DRUG: Deferiprone oral solution 100mg/mL|DRUG: Deferiprone oral solution 100 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: norUrsodeoxycholic Acid vs Placebo in PSC
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Sclerosing Cholangitis
Interventions: DRUG: norUrsodeoxycholic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Voriconazole Versus Oral Steroids in Allergic Bronchopulmonary Aspergillosis
Status: COMPLETED
Conditions: Allergic Bronchopulmonary Aspergillosis
Interventions: DRUG: Prednisolone|DRUG: Voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Diclofenac for Retinal Photocoagulation in Diabetic Retinopathy
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: potassium diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Immediate Effects of Ankle Mobilization on Dorsiflexion Range of Motion in Women With Patellofemoral Pain.
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Manual Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of OASIS Ultra on Critical Sized Wound Healing
Status: COMPLETED
Conditions: Traumatic Wound|Infective Wound|Iatrogenic Critical Sized Wound Defects|Wound Healing
Interventions: DEVICE: OASIS Ultra|DEVICE: Wound VAC Standard Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis|IBD
Interventions: DRUG: Brazikumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Equity Report Cards to Mitigate Disparities in Emergency Medical Services (EMS) Care for Injured Children
Status: NOT_YET_RECRUITING
Conditions: Pain, Acute
Interventions: OTHER: Equity Report Cards
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cardiovascular Diseases and Diabetes Prevention Programme in Metabolic Syndrome (CDPP)
Status: NOT_YET_RECRUITING
Conditions: Metabolic Syndrome
Interventions: DRUG: Berberine|BEHAVIORAL: Healthy lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Evaluation of Effectiveness Between Empirical and Guided Therapy for Unexplained Non-Cardiac Chest Pain
Status: COMPLETED
Conditions: Non Cardiac Chest Pain
Interventions: DRUG: Empirical therapy group|DRUG: Guided therapy group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Masked, Placebo-Controlled Two Cross Over Study Comparing the Effects of Moxaverine and Placebo on Ocular Blood Flow
Status: COMPLETED
Conditions: Ischemia
Interventions: DRUG: Moxaverine|DRUG: physiological saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of FSH on Endothelial Function (FEND)
Status: UNKNOWN
Conditions: Change in Flow Mediated Dilation
Interventions: DRUG: Follicle Stimulating Hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intensive Lipid-lowering in Patients With STEMI and NSTEMI (Germany on Target)
Status: NOT_YET_RECRUITING
Conditions: ST Elevation Myocardial Infarction|Non-ST Elevation Myocardial Infarction|LDL-cholesterol
Interventions: DRUG: statins, ezetimibe, bempedoic acid, evolocumab, alirocumab, inclisiran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Creatine Supplementation on Physical Performance in Vegan Subjects
Status: RECRUITING
Conditions: Deficiency; Diet
Interventions: DIETARY_SUPPLEMENT: Creatine Supplementation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MEN1611 With Cetuximab in Metastatic Colorectal Cancer (C-PRECISE-01)
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: MEN1611|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness Of Low Extra-Corporeal Shock Wave Versus Acetylcholine Iontophoresis On Type2 Diabetic Neuropathy
Status: NOT_YET_RECRUITING
Conditions: Diabetic Nephropathy
Interventions: DEVICE: Low-intensity extracorporeal shock wave
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Carmustine Implants and O(6)-Benzylguanine in Treating Children With Recurrent Malignant Glioma
Status: TERMINATED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: O6-benzylguanine|DRUG: polifeprosan 20 with carmustine implant|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Pharmacogenetics to Predict Drug Interactions in Kidney Transplant Recipients
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Tacrolimus + Ketoconazole, Then Tacrolimus alone|DRUG: Tacrolimus alone, Then Tacrolimus + Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Text Message Intervention to Promote Health Behaviors in Cardiac Risk Conditions
Status: COMPLETED
Conditions: Hyperlipemia|Hypertension|Type2 Diabetes
Interventions: BEHAVIORAL: Text Message Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of TVB-2640 in Subjects With Nonalcoholic Steatohepatitis (NASH)
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver Disease
Interventions: DRUG: TVB-2640|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Andecaliximab in Participants With Fibrodysplasia Ossificans Progressiva (FOP)
Status: NOT_YET_RECRUITING
Conditions: Fibrodysplasia Ossificans Progressiva
Interventions: DRUG: Andecaliximab|DRUG: Placebo|DRUG: Andecaliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Follow-up Study to Examine the Presence of Anti-human Growth Hormone Antibodies Following a Study (FE 999905 CS07) of Zomacton in Children With Growth Hormone Deficiency
Status: COMPLETED
Conditions: Idiopathic Growth Hormone Deficiency
Interventions: PROCEDURE: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: An Open Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other Immunodeficiencies
Status: COMPLETED
Conditions: Herpes Simplex|HIV Infections
Interventions: DRUG: Foscarnet sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Curcuminoids in the Treatment of Oral Lichen Planus
Status: COMPLETED
Conditions: Oral Lichen Planus
Interventions: DRUG: Curcuminoids|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurally Adjusted Ventilatory Assist (NAVA) vs. Pressure Support in Pediatric Acute Respiratory Failure
Status: UNKNOWN
Conditions: Pediatric Acute Respiratory Failure
Interventions: PROCEDURE: Non invasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Trial of G-CSF Alone Versus Intermediate-dose Ara-C Plus G-CSF Mobilization in Multiple Myeloma Patients.
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: G-CSF (filgrastim)|DRUG: Cytosine arabinoside + G-CSF (filgrastim)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Optimal Dosing Conditions for GLP-1 Analogue NNC0113-0987 When Administered Orally in Healthy Male Subjects
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: NNC0113-0987
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Transvaginal vs. Conventional Laparoscopic Cholecystectomy on the Postoperative Course
Status: TERMINATED
Conditions: Cholecystolithiasis|Surgery|Pain
Interventions: PROCEDURE: TV NOTES cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Insulin Therapy Augmented by Real Time Sensor IN Type 1 Children and Adolescents (START-IN!)
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: monitor Paradigm 754 VEO, MINILINK Real Time, Medtronic, CE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of HIP2101 in Patients With Acute or Chronic Gastritis
Status: COMPLETED
Conditions: Gastritis
Interventions: DRUG: HIP2101|DRUG: RLD2101|DRUG: HPP2101|DRUG: HPP2102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Saffron Mouth Rinse in Periodontitis Patients With Renal Disease
Status: RECRUITING
Conditions: Periodontal Diseases|Periodontal Pocket|Periodontal Inflammation
Interventions: OTHER: Saffron|OTHER: chlorhexidine mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 1MoreStep: An Intervention to Increase HIV Care Engagement and Reduce Intimate Partner Violence Among Black Women Living With HIV
Status: RECRUITING
Conditions: Violence, Domestic|HIV|Stigma, Social|Engagement, Patient|Medication Adherence
Interventions: BEHAVIORAL: 1MoreStep|BEHAVIORAL: 1MoreStepControl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Neural Markers and Rehabilitation of Executive Functioning in Veterans With Traumatic Brain Injury and Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Traumatic Brain Injury|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Cognitive Rehabilitation Intervention|BEHAVIORAL: Cognitive Rehabilitation Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Mucosal Tissue Thickness on Soft and Hard Tissue Changes Around Implants
Status: UNKNOWN
Conditions: Post-osseointegration Biological Failure of Dental Implant|Alveolar Bone Loss
Interventions: DEVICE: Dentsply Astra Tech Implant System EV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Pilot Trial of Transnasal Nicotine in Parkinson Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Nicotine Nasal Spray 10 MG/ML (0.5 MG/SPRAY)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Steady-State Study of Extended Phenytoin Sodium Capsules 100 mg and Dilantin® Kapseals® 100 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Extended Phenytoin Sodium Capsules 100 mg|DRUG: Dilantin® Kapseals® 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Autologous and Allogenic Transplantation With Campath-1H for T-Cell Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: DRUG: Campath-1H|DRUG: G-CSF|DRUG: GM-CSF|DRUG: BCNU|DRUG: Stem Cell Transplant|DRUG: Preparative Regimen for Allogenic Stem Cell Transplantation|DRUG: Cytarabine|DRUG: Etoposide|DRUG: Melphalan|DRUG: Campath|DRUG: Fludarabine|DRUG: Cyclophosphamide|RADIATION: Low dose total body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)
Status: RECRUITING
Conditions: Pediatric Solid Tumor|Osteosarcoma|Rhabdomyosarcoma|Neuroblastoma|Ewing Sarcoma|Wilms Tumor|Adrenocortical Cancer|Desmoplastic Small Round Cell Tumor|Germ Cell Cancer|Rhabdoid Tumor|Clear Cell Sarcoma|Hepatoblastoma|Melanoma|Carcinoma|Malignant Peripheral Nerve Sheath Tumors|Soft Tissue Sarcoma
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: MESNA|DRUG: B7-H3 CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Values Clarification and Attitude Transformation Workshops on Abortion and Family Planning Service Provision and Client Experience
Status: COMPLETED
Conditions: Abortion|Contraception
Interventions: BEHAVIORAL: Values Clarification and Attitudes Transformation (VCAT) Workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Proficiency Based Training in Surgery - Employing An Arthroscopic Bankart Repair
Status: COMPLETED
Conditions: Study Focus: Simulation and Proficiency Based Training
Interventions: BEHAVIORAL: Group B - Simulation Training|BEHAVIORAL: Group C - Proficiency Based Progression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: sEphB4-HSA Before Surgery in Treating Patients With Bladder Cancer, Prostate Cancer, or Kidney Cancer
Status: TERMINATED
Conditions: Infiltrating Bladder Urothelial Carcinoma|Recurrent Bladder Carcinoma|Stage I Prostate Cancer|Stage I Renal Cell Cancer|Stage II Bladder Urothelial Carcinoma|Stage II Renal Cell Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer|Stage III Prostate Cancer|Stage III Renal Cell Cancer
Interventions: OTHER: Cytology Specimen Collection Procedure|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Radical Cystectomy|BIOLOGICAL: Recombinant EphB4-HSA Fusion Protein|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Biomarker ResearcH Study of Palbociclib Combined With Endocrine Therapy in Estrogen Receptor Positive/HER2 Negative Breast CAncer (NeoRHEA)
Status: COMPLETED
Conditions: Breast Cancer Female
Interventions: DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Look at Similarity Between Semaglutide Versions in Different Injection Tools
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Semaglutide, 0.5 mg/mL|DRUG: Semaglutide, 1.0 mg/mL|DRUG: Semaglutide, 1.34 mg/mL|DRUG: Semaglutide, 2.0 mg/mL|DEVICE: DV3372, 0.5 mg/mL|DEVICE: DV3372, 1.0 mg/mL|DEVICE: PDS290|DEVICE: NovoPen®4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metacarpophalangeal Joint Prostheses in Hand Surgery.
Status: RECRUITING
Conditions: Osteoarthritis Metacarpophalangeal Joint|Rheumatoid Arthritis Metacarpophalangeal Joint
Interventions: PROCEDURE: Metacarpophalangeal joint prostheses|PROCEDURE: Metacarpophalangeal joint prostheses
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Diclofenac Sodium Gel (DSG) in Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Diclofenac Sodium Gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Loupe-Assisted Varicocelectomy With Nitroglycerin Instillation and Microscopic Varicocelectomy
Status: COMPLETED
Conditions: Varicocele
Interventions: PROCEDURE: subinguinal loupe-assisted varicocelectomy (LV)|PROCEDURE: subinguinal microscopic varicocelectomy (MV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypoalgesic Effect of Neural Mobilization Versus Ibuprofen Pharmacologic Treatment
Status: COMPLETED
Conditions: Cervicobrachial Neuralgia
Interventions: PROCEDURE: Median Nerve Neural Mobilization|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact Evaluation of a School-Based Sexuality and HIV Prevention Education Activity in South Africa
Status: COMPLETED
Conditions: HSV-2 Infection|HIV Infections|Pregnancy Related
Interventions: BEHAVIORAL: School-based sexuality and HIV prevention scripted lesson plans
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Transfemoral Powered Foot and Physical Therapy Study
Status: RECRUITING
Conditions: Lower Extremity Problem|Prosthesis User
Interventions: BEHAVIORAL: Powered device with physical therapy|BEHAVIORAL: Powered device with standard of practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Anaplastic Astrocytoma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: carmustine|DRUG: cisplatin|DRUG: etoposide|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ib Study of PI3(Phosphoinositol 3)-Kinase Inhibitor Copanlisib With MEK (Mitogen-activated Protein Kinase) Inhibitor Refametinib (BAY86-9766) in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Copanlisib + Refametinib (BAY86-9766)|DRUG: Copanlisib + Refametinib (BAY86-9766)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Melatonin on Elevated Liver Enzymes During Statins Treatment
Status: COMPLETED
Conditions: Hepatopathy
Interventions: DRUG: Melatonin 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sildenafil Citrate for the Management of Asymmetrical Intrauterine Growth Restriction
Status: UNKNOWN
Conditions: Intrauterine Growth Restriction
Interventions: DRUG: Sildenafil citrate|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Local Changes of Skin Characteristics After an Application of a Topical Product With a Warming or Cooling Effect
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Axanova hot gel|OTHER: Axanova activ gel|OTHER: Perskindol Dolo Gel|OTHER: Perskindol Classic Gel|OTHER: Perskindol Cool Kühl-Gel|OTHER: Dolor-X Hot Gel|OTHER: Dolor-X Classic Gel|OTHER: Dolor-X Cool Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: JAK Inhibitor Before Donor Stem Cell Transplant in Treating Patients With Primary or Secondary Myelofibrosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Myelofibrosis|Secondary Myelofibrosis
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Busulfan|DRUG: Cyclophosphamide|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan|DRUG: Methotrexate|DRUG: Mycophenolate Mofetil|DRUG: Ruxolitinib|DRUG: Tacrolimus|RADIATION: Total-Body Irradiation|PROCEDURE: Umbilical Cord Blood Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Immunogenicity and Reactogenicity of a Pneumococcal Conjugate Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Streptococcus Pneumoniae
Interventions: BIOLOGICAL: pneumococcal conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neurobiology of Bulimia Nervosa
Status: COMPLETED
Conditions: Bulimia Nervosa
Interventions: DRUG: Estradiol|DRUG: Micronized progesterone|DRUG: Leuprolide Acetate|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of the Safety and Efficacy of Balstilimab for the Treatment of Relapsed/Refractory Lymphomas (IMMONC0001)
Status: RECRUITING
Conditions: Lymphoma
Interventions: DRUG: Balstilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging Methods for the Diagnosis of Non-melanoma Skin Cancer and Its Precursors
Status: COMPLETED
Conditions: Non-melanoma Skin Cancer
Interventions: DEVICE: optical coherence tomography, in vivo reflectance confocal microscopy, 3D total body photography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pioglitazone Hydrochloride in Preventing Head and Neck Cancer in Patients With Oral Leukoplakia
Status: COMPLETED
Conditions: Head and Neck Cancer|Oral Leukoplakia
Interventions: DRUG: pioglitazone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study in Patients With Trichotillomania
Status: COMPLETED
Conditions: Trichotillomania
Interventions: DRUG: SXC-2023|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Population-based Brest Stroke Registry
Status: RECRUITING
Conditions: Cerebral (CVAs)|Ischemic Cerebrovascular Accident|Stroke|Brain Ischemia|Brain Hemorrhage|Ischemic Stroke|Hemorrhagic Stroke|Cerebrovascular Disorders|Transient Ischemic Attack (TIA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy & Safety of 980nm Diode Laser vs. Cryotherapy for Plantar Warts
Status: COMPLETED
Conditions: Warts of Foot
Interventions: OTHER: Liquid nitrogen sprayed|OTHER: 980nm diode laser applied
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Negative Pressure Wound Therapy With the Engenex™-Pump and Bio-Dome™ Dressing, an Evaluation
Status: COMPLETED
Conditions: Wounds
Interventions: DEVICE: Engenex™ pump and Bio-Dome™ Wound Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pelvic Floor Disorder Assessment of Knowledge and Symptoms: an Educational Model in Spanish-Speaking Women
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|Urinary Incontinence|Patient Education
Interventions: OTHER: Educational Intervention with video
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Combined Access Closed Tympanomastoidectomy: Microsurgery Allied to Endoscopy
Status: UNKNOWN
Conditions: Cholesteatoma|Chronic Otitis Media
Interventions: PROCEDURE: combined access tympanomastoidectomy|PROCEDURE: standard closed tympanomastoidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Immunotherapy With Avelumab and Pepinemab As Second Line For Patients With Metastatic Pancreatic Adenocarcinoma
Status: RECRUITING
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: Avelumab and Pepinemab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Pharmacokinetics Study of Complarate (Tocilizumab Biosimilar Solution) and Actemra® in Healthy Volunteers
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: Complarate|BIOLOGICAL: Actemra®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Clinical Study in Adult Patients With Purulent-inflammatory Processes of the Skin and Soft Tissues, Phase I-II of the Wound Process
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot Infections|Chronic Venous Insufficiency
Interventions: DRUG: Foscelantan|DRUG: Povidon-iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plan Block, Ultrasound or Laparoscopic?
Status: COMPLETED
Conditions: Bupivacaine|Anesthetics, Local|Anesthetics|Peripheral Nervous System Agents
Interventions: DRUG: bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Aranesp and Neulasta in Patients With Sarcoma Receiving Adriamycin and Ifosfamide
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: Aranesp (darbepoetin alfa)|DRUG: Neulasta (pegfilgrastim)|DRUG: Adriamycin|DRUG: Ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: IVPCA in the Management of Pain Following Major Intracranial Surgery
Status: COMPLETED
Conditions: Intracranial Surgery
Interventions: DRUG: PCA fentanyl|DRUG: PRN fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Soluble Vascular Endothelial Growth Factor Receptor 2 as Predictor of Benefit From Bevacizumab Beyond Progression in Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: chemotherapy plus bevacizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Timing of Postoperative Drain Removal Following Parotidectomy - a Prospective Randomized Controlled Study
Status: UNKNOWN
Conditions: Parotidectomy
Interventions: OTHER: Early Drain Removal|OTHER: Late Drain Removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life in Patients With Obstructive Sleep Apnea: The Role of CPAP Associated to Psychological Support
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea|Depressive Symptoms
Interventions: BEHAVIORAL: CPAP and Psychological support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Desvenlafaxine for Treatment of Hot Flashes in Women With Breast Cancer Taking Tamoxifen
Status: TERMINATED
Conditions: Hot Flashes|Breast Neoplasms
Interventions: DRUG: Desvenlafaxine succinate 100mg|DRUG: Desvenlafaxine succinate 50mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antineoplaston Therapy in Treating Patients With Soft Tissue Sarcoma
Status: TERMINATED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perinatal Handwashing Intervention in Bangladesh
Status: COMPLETED
Conditions: Sepsis|Umbilical Cord|Infection
Interventions: BEHAVIORAL: Perinatal Handwashing Promotion|BEHAVIORAL: Neonatal Health Promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION