pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Associations Between Early Neonatal Neuroimaging, Hammersmith Infant Neurological Examination and General Movements
Status: COMPLETED
Conditions: Cerebral Palsy|Infant, Premature, Diseases|Infant Development|Neurologic Disorder|Development Delay|Infant Asphyxia|Infant, Small for Gestational Age|Infant, Newborn, Disease|Infant, Very Low Birth Weight
Interventions: DIAGNOSTIC_TEST: Measurements
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I Pilot Study of Liver-Directed Gene Therapy for Partial Ornithine Transcarbamylase Deficiency
Status: TERMINATED
Conditions: Ornithine Transcarbamylase Deficiency Disease
Interventions: GENETIC: recombinant adenovirus containing the ornithine transcarbamylase gene
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of a 6-Months Physical Conditioning Program in Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: BEHAVIORAL: Supervised aerobic training|BEHAVIORAL: Supervised strength training|BEHAVIORAL: Unsupervised training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abdominal Aortic Aneurysm Follow-up After Endovascular Repair by Non-invasive Vascular Elastography
Status: COMPLETED
Conditions: Aortic Aneurysm Abdominal|Endovascular Aneurysm Repair (EVAR)
Interventions: OTHER: QSE-LSME - SSWI Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ultrasound-guided Arterial Catheterization in Pediatric Patients
Status: COMPLETED
Conditions: Ultrasound|Arterial Catheterization|Child
Interventions: OTHER: Long-axis/in-plane US-guided arterial catheterization|OTHER: Short-axis/out-of-plane US-guided arterial catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose-ranging Study of an Investigational Yellow Fever Candidate Vaccine in Adults
Status: COMPLETED
Conditions: Yellow Fever (Healthy Volunteers)
Interventions: BIOLOGICAL: Yellow fever vaccine (produced on serum-free Vero cells), Dosage 1 vYF vaccine|BIOLOGICAL: Yellow fever vaccine (produced on serum-free Vero cells), Dosage 2 vYF vaccine|BIOLOGICAL: Yellow fever vaccine (produced on serum-free Vero cells), Dosage 3 vYF vaccine|BIOLOGICAL: Yellow fever vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Gardemont S.A Food Supplement on Upper Respiratory Illness
Status: UNKNOWN
Conditions: Respiratory Infections
Interventions: DIETARY_SUPPLEMENT: Gardemont Goldtrain Plus (GT+)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Learn if Odronextamab Combined With Lenalidomide is Safe and Works Better Than Rituximab Combined With Lenalidomide in Adult Participants With Follicular Lymphoma and Marginal Zone Lymphoma
Status: RECRUITING
Conditions: Relapsed/Refractory Follicular Lymphoma|Marginal Zone Lymphoma (MZL)
Interventions: DRUG: Odronextamab|DRUG: Lenalidomide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venous Thrombosis Prevention and Sleep Quality: A Comparison of the Kendall and the Recovery Health MAC Systems
Status: COMPLETED
Conditions: Deep Venous Thrombosis of Deep Femoral Vein
Interventions: DEVICE: RF Health MAC Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Study of Endovascular Interventional Surgical Instrument Control System and Related Consumables in Percutaneous Coronary Intervention
Status: NOT_YET_RECRUITING
Conditions: Percutaneous Coronary Intervention|Coronary Heart Disease|Robotic Surgical Procedures
Interventions: DEVICE: ALLVAS® robotic-assisted PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect on Quality of Life of Adapted Information in Pulmonary Rehabilitation in Chronic Respiratory Disease Patients
Status: COMPLETED
Conditions: Chronic Respiratory Disease
Interventions: OTHER: Adapted information arm|OTHER: Neutral information arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reduced-fluence Verteporfin Photodynamic Therapy Plus Ranibizumab for Choroidal Neovascularization in Pathologic Myopia
Status: COMPLETED
Conditions: Myopia, Degenerative
Interventions: DRUG: PDT standard fluence, ranibizumab|DRUG: PDT reduced fluence, ranibizumab|DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Oral Doses of BI135585 XX Administered as Tablet and as Solution in Healthy Volunteers
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo to BI 135585|DRUG: BI 135585
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: EFFECTIVENESS OF A PROGRAM OF DOMICILIARY EXERCISES AGAINST HABITUAL CLINICAL PRACTICE IN THE RECURRENCE OF ACUTE LOW BACK PAIN: RANDOMIZED CLINICAL TRIAL
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: OTHER: Standard of care (exercise)|OTHER: Domicilary exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the BiTE® Blinatumomab (MT103) in Adult Patients With Relapsed/Refractory B-Precursor Acute Lymphoblastic Leukemia (ALL)
Status: COMPLETED
Conditions: B-ALL
Interventions: BIOLOGICAL: Blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture in Herpes Zoster Neuralgia (ACUZoster)
Status: COMPLETED
Conditions: Herpes Zoster|Postherpetic Neuralgia|Pain
Interventions: DEVICE: Sham-laser acupuncture|DRUG: gabapentine|PROCEDURE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Reduction Internal Fixation of Calcaneus Fractures With and Without Bone Graft
Status: COMPLETED
Conditions: Calcaneus Fractures
Interventions: PROCEDURE: ORIF of Calcaneus with bone grafting|PROCEDURE: ORIF of Calcaneus without bone grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intestinal Inflammation in Ankylosing Spondylitis and the Effects of Adalimumab on Mucosal Healing
Status: COMPLETED
Conditions: Spondyloarthritis|Enterocolitis
Interventions: DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Open Hemorrohoidectomy Vs Transanal Hemorrhoidal Desarterialization in Hemorrhoids Grade III: The Effect on Symptoms
Status: COMPLETED
Conditions: Hemorrhoids Third Degree
Interventions: PROCEDURE: Open Hemorrhoidectomy|PROCEDURE: Transanal Hemorrhoidal Dearterialization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperosmolar Saline Irrigation Fluid in Arthroscopic Knee Surgery
Status: COMPLETED
Conditions: Arthroscopic Knee Surgery
Interventions: DRUG: Hyperosmolar Saline|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of a New Intermittent Pneumatic Compression Device to Treat Patients With Peripheral Arterial Disease (PAD) Stage II
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: AngioPress Intermittent pneumatic compression (IPC) Device|OTHER: Medications and Standard walking exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Addition to an Antiretroviral Treatment of a Probiotic
Status: COMPLETED
Conditions: HIV|Premature Aging
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Prebiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy in Combination With Chemoradiotherapy in Unresectable Locally Advanced Esophageal Cancer
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma|Unresectable Locally Advanced Esophageal Cancer
Interventions: DRUG: PD-1inhibitor|DRUG: nab-paclitaxel + cisplatin|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contrast-Enhanced Ultrasound Scan for the Estimation of Tissue Pressure in Patients With Breast Cancer
Status: RECRUITING
Conditions: Breast Carcinoma
Interventions: PROCEDURE: Ultrasonsgraphy|DRUG: Perflutren Lipid Microcpheres|PROCEDURE: Contrast - Enhanced Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Influence of Plasma Rich in Growth Factors (PRGF) on Healing of Medial Collateral Ligament (MCL) Tear
Status: WITHDRAWN
Conditions: MCL Tear
Interventions: BIOLOGICAL: Plasma Rich in Growth Factors (PRGF)|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Intraradicular Cryotherapy on Post-operative Pain and the Level of Substance P
Status: RECRUITING
Conditions: Post Operative Pain|Inflammation
Interventions: OTHER: cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravitreal Bevacizumab on Non -Age-Related Macular Degeneration (AMD) Related Choroidal Neovascularization (CNV)
Status: COMPLETED
Conditions: Choroidal Neovascularization
Interventions: DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Healthy Volunteer Safety Pharmacokinetics Study
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: PF03635659|DRUG: PF03635659|DRUG: PF03635659|DRUG: PF03635659|DRUG: PF03635659
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Hormone Replacement Therapy for Hot Flashes and/or Vaginal Symptoms in Postmenopausal Women Receiving Tamoxifen for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Hot Flashes|Menopausal Symptoms
Interventions: DRUG: conjugated estrogens|DRUG: medroxyprogesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Efficacy of Infliximab Induction Therapy for Patients With Palmoplantar Psoriasis (PPP)(Study P04555)(COMPLETED)
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Additional Effects of Using TENS and Interferential Currents for the Treatment of Individuals With Chronic Nonspecific Neck Pain.
Status: RECRUITING
Conditions: Neck Pain|Chronic Pain
Interventions: OTHER: Therapeutic exercise|OTHER: Therapeutic exercise group + high frequency TENS|OTHER: Therapeutic exercise group + Interferential
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Selenium on Serum Adiponectin, Homocystein and Malnutrition-inflammation Complex Syndrome in Hemodialysis Patients
Status: COMPLETED
Conditions: Oxidative Stress|Inflammation|Malnutrition
Interventions: DIETARY_SUPPLEMENT: Selenium Supplement|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improvements in Cognitive Skills of Older Adults Using Dynamic Visual Attention Training
Status: WITHDRAWN
Conditions: Age Related Cognitive Decline
Interventions: BEHAVIORAL: PATH neurotraining|BEHAVIORAL: Orientation Discrimination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Immune Nutrition Diet on 90-Day Outcomes in Patients Undergoing Radical Cystectomy
Status: UNKNOWN
Conditions: Bladder Cancer|Oncology|Infection|Complication|Muscle Invasive|Radical Cystectomy
Interventions: DRUG: Bio-tech and omega-3 plus|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Aripiprazole and Olanzapine in the Treatment of Patients With Acute Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole|DRUG: Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Seroprevalence of IgG Antibodies to SARS-CoV-2 (COVID-19) in Primary Health Care Workers and Their Household Contacts
Status: COMPLETED
Conditions: Covid19
Interventions: DIAGNOSTIC_TEST: Serological test for the detection of IgG anti-SARS-CoV-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Using a Novel Functional MRI Technique to Evaluate for Neurotoxicity
Status: COMPLETED
Conditions: Central Nervous System Lymphoma
Interventions: DIAGNOSTIC_TEST: Resting State fMRI (rsfMRI)|OTHER: Auditory Attention and Executive Functions Test|OTHER: Memory Test|OTHER: Motor Speed Test|OTHER: Self Reported Quality of Life Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Gastroesophageal Reflux Disease in Infants
Status: NOT_YET_RECRUITING
Conditions: Gastroesophageal Reflux|Infant, Newborn, Diseases
Interventions: DRUG: Protein pump inhibitor. Continuing nutrition containing cows' milk protein.|BEHAVIORAL: Mother or infant diet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Bariatric Surgery on Pharmacokinetic Study of Simvastatin and Carvedilol
Status: UNKNOWN
Conditions: Obesity|Bariatric Surgery|Roux-en Y Gastric Bypass
Interventions: PROCEDURE: Digestive biopsy|DRUG: Carvedilol 25mg|PROCEDURE: Serial blood sampling for PK analysis|DRUG: Metoprolol 100 mg for CYP2D6 phenotyping|DRUG: Simvastatin 40mg|DRUG: Midazolam 2 mg for CYP3A4 phenotyping|OTHER: Genotyping
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Parietal Peritoneum as a Substitute Graft for Venous Reconstruction in HPB Surgery
Status: UNKNOWN
Conditions: Safety|Availability|Venous Patency|Oncological Benefits|Morbidity
Interventions: PROCEDURE: venous reconstruction with the parietal peritoneum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Blood and Tissue Samples in Children With Newly Diagnosed Acute Lymphoblastic Leukemia
Status: UNKNOWN
Conditions: Leukemia|Lymphoma
Interventions: GENETIC: gene expression analysis|GENETIC: mutation analysis|GENETIC: polymorphism analysis|OTHER: biologic sample preservation procedure|OTHER: laboratory biomarker analysis|OTHER: pharmacogenomic studies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Echo-Focusing in Patients With Treatment-Resistant Neurologic and Psychiatric Indications (EF001)
Status: NOT_YET_RECRUITING
Conditions: Essential Tremor|Neurology
Interventions: DEVICE: Exablate Neuro Type 1.0 System with Echo Focusing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of the Safety and Pharmacokinetics of AGS-16M18 in Subjects With Advanced Renal Cell Cancer
Status: TERMINATED
Conditions: Carcinoma, Renal Cell|Kidney Neoplasms|Kidney Diseases
Interventions: BIOLOGICAL: AGS-16M18
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MOTION, Safinamide in Early Idiopathic Parkinson's Disease (IPD), as add-on to Dopamine Agonist (Extension of Trial 27918)
Status: TERMINATED
Conditions: Idiopathic Parkinson's Disease
Interventions: DRUG: Safinamide, MAO-B inhibitor|DRUG: Safinamide, MAO-B inhibitor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Exploratory Efficacy of CARTISTEM®, a Cell Therapy Product for Articular Cartilage Defects
Status: COMPLETED
Conditions: Degeneration Articular Cartilage Knee
Interventions: BIOLOGICAL: CARTISTEM®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of the Time of Day in the Effect of Caffeine on Maximal Fat Oxidation During Exercise in Women
Status: COMPLETED
Conditions: Dietary Supplement
Interventions: DIETARY_SUPPLEMENT: Acute caffeine supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of Immunomodulation With A Monoclonal Antibody Against CD40L in Combination With Transplanted Islet Cells in Adults With Brittle Type 1 Diabetes Mellitus (T1D)
Status: RECRUITING
Conditions: Diabetes Mellitus
Interventions: DRUG: AT-1501
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repeated Bone Marrow Transplantation in Treating Women With Advanced Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: CAF regimen|DRUG: carboplatin|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: fluorouracil|DRUG: ifosfamide|DRUG: melphalan|DRUG: paclitaxel|DRUG: thiotepa|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: samarium Sm 153 lexidronam pentasodium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Riboflavin on Moderate to Severe Plaque Type Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Riboflavin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Telmisartan With or Without Hydrochlorothiazide (HCTZ) Compared With Losartan With or Without HCTZ in Mild to Moderate Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan|DRUG: Losartan|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Bridging PK Profile of FB825 for Single Subcutaneous Administration in Healthy Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: FB825 or Placebo in subcutaneous route|DRUG: FB825 in intravenous route
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Shorter Course Radiation for the Treatment of Breast Cancer That Has Spread to Lymph Nodes
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: COMBINATION_PRODUCT: Adjuvant Hypofractionated Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study Investigating NNC0247-0829 for Weight Management in People With Overweight or Obesity
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DRUG: NNC0247-0829|DRUG: Placebo (NNC0247-0829)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of Exenatide Action on Vessel Function in Type 2 Diabetes and Prediabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Exenatide SC|DRUG: Exenatide IV|DRUG: Placebo SC|DRUG: Exendin-9|DRUG: Placebo IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dietary and Exercise Interventions in Preventing Cardiovascular Disease in Younger Survivors of Leukemia, Lymphoma, or Brain Tumors
Status: WITHDRAWN
Conditions: Childhood Brain Tumor|Childhood Hodgkin Lymphoma|Childhood Non-Hodgkin Lymphoma|Malignant Childhood Neoplasm
Interventions: BEHAVIORAL: Specimen Collection/Risk Factor Assessment -> Diet/Exercise -> Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adherence to the iFightDepression Online Self-help Tool for Mild and Moderate Depression
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: iFightDepression online self-help tool|BEHAVIORAL: Treatment as Usual|BEHAVIORAL: phone call
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Emotion Regulation Intervention to Sustain Physical Activity in Rural-dwelling Women and Men After Myocardial Infarction
Status: COMPLETED
Conditions: Cardiac Event|Emotions
Interventions: BEHAVIORAL: eMotion|BEHAVIORAL: Healthy Living Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Primary Peritoneal Carcinoma|Stage III Ovarian Cancer|Stage IV Ovarian Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Gemcitabine Hydrochloride|DRUG: Pegylated Liposomal Doxorubicin Hydrochloride|DRUG: Topotecan Hydrochloride|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stapler Versus Glue for Laparoscopic Groin Hernia Repair
Status: COMPLETED
Conditions: Inguinal Hernia|Recurrence|Pain
Interventions: PROCEDURE: Mesh fixation by staples|PROCEDURE: Mesh fixation by glue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of High-Intensity Interval Training on Physical Fitness, Skills, and Tactical Performance, 12 Weeks High-Intensity Interval Training
Status: RECRUITING
Conditions: Power, Personal
Interventions: BEHAVIORAL: Assigned Interventions|BEHAVIORAL: Random Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilocarpine in Treating Patients With Dry Mouth Caused by Opioids
Status: TERMINATED
Conditions: Oral Complications|Quality of Life
Interventions: DRUG: pilocarpine hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Etomidate on Postoperative Circadian Rhythm Changes of Salivary Cortisol in Children
Status: UNKNOWN
Conditions: Congenital Hydronephrosis|Congenital Choledochal Cyst|Fracture
Interventions: DRUG: etomidate|DRUG: midazolam|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Healthy Bones, Healthy Life: Habitual Physical Activity on Bone & Metabolic Health in Pediatric Cancer Survivors
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia, Pediatric|Pediatric ALL|Pediatric Lymphoma|Bone Loss|Metabolic Syndrome|Habitual Physical Activity|Precursor Cell Lymphoblastic Leukemia|Lymphoma|Leukemia|Lymphoid Leukemia|Pediatric|Osteoporosis|Osteoporosis Risk
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Simultaneous Versus Staged Resection for Initially Resectable Synchronous Rectal Cancer Liver-limited Metastasis
Status: COMPLETED
Conditions: Rectal Neoplasm With Metastasis to the Liver
Interventions: PROCEDURE: simultaneous resection of liver metastasis and the rectal primary tumor|PROCEDURE: staged resection of liver metastasis and the rectal primary tumor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Crossover Study to Assess the Effects of Dietary Fiber-containing Bars on Glucose and Insulin Responses
Status: COMPLETED
Conditions: Blood Glucose|Insulin Sensitivity|Dietary Fiber
Interventions: OTHER: Medium-fiber bar|OTHER: High-fiber bar|OTHER: Control bar (0 g fiber)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy Study of School-located Influenza Vaccination Clinics to Increase Influenza Vaccination Rates in Monroe County, New York
Status: COMPLETED
Conditions: Childhood Influenza Vaccination|School-located Influenza Vaccination
Interventions: OTHER: School-located Influenza Vaccination Clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy Study of Panitumumab+Irinotecan in Patients Wild-Type (WT) KRAS Metastatic Colorectal Cancer Refractory to Irinotecan Based Chemotherapy (SPECTRA)
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Panitumumab+irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FallsTalk Falls Prevention Program for Caregivers and Persons With Memory Loss or Dementia
Status: UNKNOWN
Conditions: Falls (Accidents) in Old Age
Interventions: BEHAVIORAL: FallsTalk-C|BEHAVIORAL: FallsTalk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hemoglobin Testing in Pregnant Patients
Status: NOT_YET_RECRUITING
Conditions: Post Partum Hemorrhage|Anemia of Pregnancy
Interventions: DEVICE: Masimo Root Radical 7 Pulse CO-Oximeter|DEVICE: HemoCue Hb 801
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MinSafeStart - Decision Aid Tool for Better Treatment of Nausea and Vomiting During Pregnancy
Status: COMPLETED
Conditions: Hyperemesis Gravidarum|Emesis|Emesis Pregnancy
Interventions: DEVICE: MinSafeStart app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy, Safety and Tolerability of ISIS 304801 in People With Partial Lipodystrophy With an Open-Label Extension
Status: COMPLETED
Conditions: Lipodystrophy
Interventions: DRUG: ISIS 304801|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Bright Light Therapy on Adolescent's Sleep Quality and Well-being
Status: COMPLETED
Conditions: Sleep Disturbance|Depression|Mood|Circadian Rhythms
Interventions: DEVICE: BWL classrooms (Experimental)|DEVICE: DWL classrooms (Comparison)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Tarceva, Temodar, and Radiation Therapy in Patients With Newly Diagnosed Brain Tumors
Status: COMPLETED
Conditions: Glioblastoma Multiforme|Gliosarcoma
Interventions: DRUG: Tarceva|DRUG: Temodar|PROCEDURE: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Intensity Physical Activity Leads to Improvement in Brachial-ankle Pulse Wave Velocity of Hemiplegics
Status: COMPLETED
Conditions: Hemiplegia|Motor Activity|Physical Activity
Interventions: BEHAVIORAL: Daily low intensity physical activity by the half squat|BEHAVIORAL: stretch exercise and usual activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: In Vitro Drug Sensitivity Testing of Fresh Human Samples
Status: NOT_YET_RECRUITING
Conditions: Myeloproliferative Disorders|Lymphoproliferative Disorders
Interventions: BIOLOGICAL: Blood collection for the evaluation of the anti-drugs sensitivity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Role of Systemic Inflammation in Increase of Cardio-vascular Risk in Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Questionnaires about food habits and tobacco|OTHER: Spirometry|OTHER: Carotid echography|OTHER: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dual-loop Target Controlled Infusion for Coadministration of Propofol and Remifentanil Guided by Narcotrend Index
Status: UNKNOWN
Conditions: Anesthesia
Interventions: DEVICE: Narcotrend|OTHER: experience
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal FT536 in Recurrent Ovarian, Fallopian Tube, and Primary Peritoneal Cancer
Status: RECRUITING
Conditions: Gynecologic Cancer|Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: FT536|DRUG: Fludarabine|DRUG: CY
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Unstable 31.A2 and 31.A3 Trochanteric Fractures. Randomised Comparison of the Proximal Femoral Nail PFN-A Short and the PFN-A Long.
Status: COMPLETED
Conditions: Unstable Proximal Femoral Fracture
Interventions: DEVICE: PFN-A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lot Consistency, Immuno, Safety of Meningococcal Vaccine GSK134612 Given With Fluarix™ to 18-55 Year-Old Adults
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Meningococcal vaccine GSK134612|BIOLOGICAL: Mencevax™ACWY|BIOLOGICAL: Fluarix™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Novel Combination Oral Agent to Treat Acne Vulgaris
Status: UNKNOWN
Conditions: ACNE VULGARIS
Interventions: DRUG: Doxycycline and S-equol|DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Care Planning for a Loved One With Dementia: Knowledge, Preparing for Decisions, and Emotions
Status: RECRUITING
Conditions: Dementia|Dementia Frontotemporal|Dementia Alzheimers|Dementia, Mild|Dementia Moderate|Dementia Severe|Caregiver Burnout|Caregiver Stress Syndrome
Interventions: OTHER: Video Intervention Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Treat-to-target Strategy Using Pan-enteric Capsule Endoscopy (PCE) in Paediatric Crohn's Disease (CD).
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Children, Only
Interventions: DEVICE: Pan-enteric Capsule Endoscopy (PCE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Community Based Intervention for Children With ADHD and ASD
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Attention Deficit-Hyperactivity Disorder|Executive Function
Interventions: BEHAVIORAL: Unstuck and on Target (UOT)|BEHAVIORAL: Parents and Teachers Supporting Students (PATSS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise and Nutrition Intervention in Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer|Malnutrition|Muscle Wasting|Fatigue
Interventions: BEHAVIORAL: combined exercise and nutrition intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Point-of-Care Computed Tomography (CT) Chronic Rhinosinusitis Study
Status: COMPLETED
Conditions: Chronic Rhinosinusitis
Interventions: PROCEDURE: Pre-treatment Sinus CT Scan|PROCEDURE: Post-treatment Sinus CT Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intravenous Ketamine Plus Neurocognitive Training for Depression
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Intravenous ketamine|BEHAVIORAL: Computer-based Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conventional or Hypofractionated Radiation Therapy in Treating Patients With Prostate Cancer
Status: RECRUITING
Conditions: Stage I Prostate Cancer AJCC v8|Stage II Prostate Cancer AJCC v8|Stage III Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8
Interventions: RADIATION: Hypofractionated Radiation Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen
Status: RECRUITING
Conditions: Acute Myelogenous Leukemia|Acute Lymphocytic Leukemia|Chronic Myelogenous Leukemia|Non-Hodgkin's Lymphoma|Hodgkin's Disease|Multiple Myeloma|Germ Cell Neoplasms|Myelodysplastic Syndromes|Chronic Lymphocytic Leukemia|Immunodeficiency Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Enhancing Psychological Skills and Well-being in Sport Through a Blended Intervention: a Controlled Study With Perform-UP Tennis
Status: COMPLETED
Conditions: Psychological Well-Being
Interventions: DEVICE: Promotion of mental training through mobile application Perform-UP Tennis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cell-free Fetal DNA Circulating in the Maternal Plasma as a Marker for Morbidly Adherent Placenta
Status: UNKNOWN
Conditions: Morbidly Adherent Placenta|Placenta Accreta|Placenta Increta|Placenta Percreta
Interventions: BIOLOGICAL: Women at high risk of MAP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chemotherapy, Filgrastim and Peripheral Stem Cell Transplantation in Patients With Chronic Myelogenous Leukemia
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: busulfan|DRUG: cyclophosphamide|DRUG: filgrastim|DRUG: recombinant interferon alfa|PROCEDURE: in vitro-treated peripheral blood stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Assessment of the Impact of N-acetylcysteine Supplementation on Physical Performance
Status: RECRUITING
Conditions: Skeletal Muscle Performance|Gene Polymorphisms
Interventions: DIETARY_SUPPLEMENT: N-acetylcysteine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome
Status: NOT_YET_RECRUITING
Conditions: Squamous Cell Carcinoma of the Oral Cavity|Squamous Cell Carcinoma of the Oropharynx|Squamous Cell Carcinoma of the Hypopharynx|Squamous Cell Carcinoma of the Larynx
Interventions: OTHER: data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TCHCCT-Zhong-Xing-Emergency-Department Ultrasound With IV Contrast in Acute Flank Pain
Status: UNKNOWN
Conditions: Acute Flank Pain
Interventions: DIAGNOSTIC_TEST: Ultrasound with IV contrast|DIAGNOSTIC_TEST: CT with IV contrast|DIAGNOSTIC_TEST: Ultrasound without IV contrast|DIAGNOSTIC_TEST: CT without IV contrast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A 24-month Phase 1 Pilot Study of AADvac1 in Patients With Non Fluent Primary Progressive Aphasia
Status: UNKNOWN
Conditions: Primary Progressive Nonfluent Aphasia
Interventions: DRUG: AADvac1 40 µg|DRUG: AADvac1 160 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The SITE Study - Dexamethasone Ophthalmic Insert In OR on Day of Surgery Versus In-office Post-Op Day 1
Status: UNKNOWN
Conditions: Cataract
Interventions: DRUG: Dexamethasone 0.4 MG [Dextenza]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temsirolimus Versus Sorafenib As Second-Line Therapy In Patients With Advanced RCC Who Have Failed First-Line Sunitinib
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Sorafenib|DRUG: temsirolimus (Torisel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study of the Efficacy and Safety of Anlotinib Combined With Penpulimab in Elderly Lung Cancer Patients
Status: RECRUITING
Conditions: Lung Cancer|Lung Carcinoma|Non Small Cell Lung Cancer|Non-small Cell Carcinoma|Lung Neoplasm
Interventions: DRUG: Anlotinib and Penpulimab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Compare the Efficacy and Safety of Pitavastatin and Pravastatin in Elderly Patients
Status: COMPLETED
Conditions: Hypercholesterolemia or Combined Dyslipidemia
Interventions: DRUG: Pitavastatin|DRUG: Pravastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Neuromuscular Warm-up on Injuries in Female Athletes
Status: COMPLETED
Conditions: Knee Injuries|Anterior Cruciate Ligament Injuries|Ankle Injuries|Lower Extremity Injuries
Interventions: OTHER: neuromuscular warm-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Metformin Induces a Dietary Restriction-like State in Human
Status: UNKNOWN
Conditions: Overweight Subjects|Metformin|Aging
Interventions: DRUG: metformin 0.85 twice daily for 6 months|BEHAVIORAL: Calorie restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of [177Lu] Lu-XT033 Injection in Patients With Metastatic Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Phase I:[177Lu]Lu-XT033 Injection|DRUG: Phase II:[177Lu]Lu-XT033 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Horizons Chronic Graft-Versus-Host-Disease Study
Status: RECRUITING
Conditions: Graft Vs Host Disease|Coping Skills|Quality of Life|Stem Cell Transplant Complications
Interventions: BEHAVIORAL: Horizons Group Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Primary Care Physicians' Use of Stop-Smoking Plans to Help Patients Who Are Smokers
Status: COMPLETED
Conditions: Tobacco Use Disorder|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BEHAVIORAL: smoking cessation intervention|OTHER: counseling intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Syndemics and Loss From the HIV Care Continuum in India - Intervention
Status: UNKNOWN
Conditions: HIV Infections
Interventions: BEHAVIORAL: Active outreach|BEHAVIORAL: Appointments|BEHAVIORAL: Financial support|BEHAVIORAL: Microenterprise|BEHAVIORAL: Enhanced counseling|BEHAVIORAL: Usual clinical care and counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Understanding Clinician Utilization of Corus CAD (Age/Sex/Gene Expression Score - ASGES) in Clinical Decision Making
Status: COMPLETED
Conditions: Coronary Artery Disease|Angina Pectoris|Chest Pain|Cardiovascular Diseases|Coronary Heart Disease|CAD|CVD|CHD
Interventions: DIAGNOSTIC_TEST: Corus CAD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiotherapy of Multiple Brain Metastases Using AGuIX®
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain Metastases, Adult|Radiotherapy
Interventions: DRUG: AGuIX®|RADIATION: Whole Brain Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telomere Disclosure and Impact on Psychological Distress and Health Behaviors
Status: COMPLETED
Conditions: Telomere Length, Mean Leukocyte
Interventions: OTHER: Telomere Disclosure Impact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of LY2157299 in Participants With Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: LY2157299|DRUG: Sorafenib|DRUG: Ramucirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Physiotherapy Plus Non-invasive Brain Stimulation Improve Motor Recovery in Children With Acquired Brain Injury?
Status: TERMINATED
Conditions: Acquired Brain Injury|Recovery of Function|Transcranial Electrical Stimulation
Interventions: DEVICE: active transcranial direct current stimulation (tDCS)|BEHAVIORAL: Physiotherapy|DEVICE: sham transcranial direct current stimulation (sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PK-PD Comparative Study of Lansoprazole Capsules and Lansoprazole Enteric-coated Capsules in Healthy Chinese Volunteers
Status: COMPLETED
Conditions: Effect of Drugs|Safety Issues
Interventions: DRUG: Lansoprazole Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Catastrophism in Fibromyalgia Patients Following Dry Needling Treatment
Status: COMPLETED
Conditions: Myofascial Pain Syndrome|Catastrophizing|Chronic Pain
Interventions: PROCEDURE: Dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT