pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Healing Study of Fractional Skin Resurfacing and Tissue Histopathology After Ellacor Treatment
Status: COMPLETED
Conditions: Wrinkle|Rhytides|Histopathology
Interventions: DEVICE: ellacor® Micro-Coring procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vital Signs Patch Early Feasibility and Usability Study v1.0
Status: COMPLETED
Conditions: Vital Signs
Interventions: DEVICE: VSP System - NEHB Configuration|DEVICE: VSP System - PAL Configuration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Fluzoparib±Apatinib Versus Chemotherapy Treatment of Physician's Choice in HER2-negative Metastatic Breast Cancer Patients With Germline BRCA Mutation
Status: RECRUITING
Conditions: Treatment in HER2-negative Metastatic Breast Cancer Patients With Germline BRCA Mutation
Interventions: DRUG: Fluzoparib; Apatinib|DRUG: Fluzoparib|DRUG: Physician's choice chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TheraT® Vectors (Vaccines) Combined With Chemotherapy to Treat HPV16 Head and Neck Cancers
Status: RECRUITING
Conditions: Human Papilloma Virus|HPV|HPV Positive Oropharyngeal Squamous Cell Carcinoma|Head and Neck Cancer
Interventions: DRUG: HB-201|DRUG: HB-202|DRUG: Carboplatin|DRUG: Paclitaxel|PROCEDURE: Transoral Robotic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telephone Counseling to Enhance the Quality and Safety of Romantic and Sexual Relationships in People Living and Aging With HIV
Status: UNKNOWN
Conditions: HIV Seropositivity
Interventions: BEHAVIORAL: Telephone-Administered Motivational Interviewing Plus Behavioral Skills Training|BEHAVIORAL: Telephone-Administered Coping Effectiveness Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Botox for Treatment of TMJ Disorder With Bruxism
Status: WITHDRAWN
Conditions: Temporomandibular Joint Disorders|Bruxism|Temporomandibular Joint Dysfunction Syndrome|Myofascial Pain Dysfunction Syndrome, Temporomandibular Joint
Interventions: DRUG: onabotulinumtoxinA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Physical Exercise And Cognitive Engagement Outcomes for Mild Neurocognitive Disorder
Status: TERMINATED
Conditions: Mild Cognitive Impairment|Memory Disorders|Mild Dementia|Impaired Cognition|Mild Cognitive Disorder|Amnestic Disorder|Dementia and Amnestic Conditions|Poor Short-term Memory|Memory Impairment|Mild Neurocognitive Disorder
Interventions: BEHAVIORAL: Computerized brain fitness training|BEHAVIORAL: Yoga|BEHAVIORAL: Wellness Education|BEHAVIORAL: Support Group (patient and partner)|BEHAVIORAL: Cognitive Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of HyQvia and Gammagard Liquid (Kiovig) in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
Status: COMPLETED
Conditions: Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Interventions: BIOLOGICAL: HYQVIA|BIOLOGICAL: 0.25% albumin placebo solution with rHuPH20|BIOLOGICAL: IGIV GAMMAGARD LIQUID/KIOVIG|BIOLOGICAL: IGIV GAMUNEX®-C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Irrigation With Antibiotic-containing Solutions on Postoperative Pain and Intra-canal Bacteria
Status: UNKNOWN
Conditions: Necrotic Pulp
Interventions: COMBINATION_PRODUCT: co-amoxiclav-clindamycin solution|COMBINATION_PRODUCT: MTAD|COMBINATION_PRODUCT: 2.5% sodium hypochlorite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Omega-3 Fatty Acids Supplementation on Endothelial Function and Inflammation
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DIETARY_SUPPLEMENT: Pro-Omega|DIETARY_SUPPLEMENT: Omega 3 Fatty Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Viracept in AIDS Patients With Mycobacterium Avium Complex Disease (MAC)
Status: COMPLETED
Conditions: Mycobacterium Avium-Intracellulare Infection|HIV Infections
Interventions: DRUG: Nelfinavir mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability Study of Topical Ciclosporin in a Psoriasis Plaque Test
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Ciclosporin 0.5% (Formulation 01B)|DRUG: Ciclosporin 1.5% (Formulation 02B)|DRUG: 0.1% betamethasone|DRUG: 0.005% calcipotriol|DRUG: Formulation 00B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The BH-Works Suicide Prevention Program for Sexual and Gender Minority Youth
Status: ENROLLING_BY_INVITATION
Conditions: Suicide|Engagement, Patient
Interventions: BEHAVIORAL: The Behavioral Health-Works Suicide Prevention Program for Sexual and Gender Minority Youth
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lifestyle Behavior Influences Among African American Patients With Stage 0-III Prostate Cancer Survivors and Their Partners
Status: RECRUITING
Conditions: Cancer Survivor|Partner|Spouse|Stage I Prostate Cancer AJCC v8|Stage II Prostate Cancer AJCC v8|Stage IIA Prostate Cancer AJCC v8|Stage IIB Prostate Cancer AJCC v8|Stage IIC Prostate Cancer AJCC v8|Stage III Prostate Cancer AJCC v8|Stage IIIA Prostate Cancer AJCC v8|Stage IIIB Prostate Cancer AJCC v8|Stage IIIC Prostate Cancer AJCC v8
Interventions: DEVICE: Accelerometer|OTHER: Ecological Momentary Assessment|OTHER: Questionnaire Administration|OTHER: Survey Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Infant Heart Surgery: Central Nervous System Sequelae of Circulatory Arrest
Status: COMPLETED
Conditions: Cardiovascular Diseases|Cerebral Anoxia|Cerebrovascular Disorders|Defect, Congenital Heart|Heart Diseases|Transposition of Great Vessels|Heart Septal Defects, Ventricular
Interventions: PROCEDURE: cardiac surgical procedures|PROCEDURE: cardiopulmonary bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison Trial of OPA-15406 Ointment in Adult Patients With Atopic DermatitisSyndrome
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: 1% OPA-15406|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Hydrogels vs Silicone Hydrogel Contact Lenses
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Pair 1 (ocufilcon D / ocufilcon D)|DEVICE: Pair 2 (ocufilcon D / enfilcon A)|DEVICE: Pair 3 (ocufilcon D / comfilcon A)|DEVICE: Pair 4 (methafilcon A / methafilcon A)|DEVICE: Pair 5 (methafilcon A / comfilcon A)|DEVICE: Pair 6 (omafilcon A / comfilcon A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Melody Transcatheter Pulmonary Valve Study: Post Approval Study of the Investigational Device Exemption Cohort
Status: COMPLETED
Conditions: Congenital Heart Defects|Dysfunctional Right Ventricular Outflow Tract Conduits
Interventions: DEVICE: Transcatheter Pulmonary Valve replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dry Pleurodesis With Talcum and Afatinib is Used to Treat Patients With Non-Small Cell Lung Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Afatinib|DRUG: Talcum powder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of IMC-A12 (Cixutumumab) With and Without Other Standard Chemotherapies in Participants With Lung Cancer Who Have Not Received Chemotherapy Before
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin|BIOLOGICAL: IMC-A12 (cixutumumab)|BIOLOGICAL: Cetuximab|BIOLOGICAL: IMC-A12 (cixutumumab)|BIOLOGICAL: Cetuximab|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MK0476 Study in Adult Patients With Acute Asthma (0476-322)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: montelukast sodium|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: REGN3918 in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate Its Long Term Safety, Efficacy and Tolerability.
Status: TERMINATED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: REGN3918
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety Study of Intramuscular Injections of 750 mg and 1000 mg Testosterone Undecanoate in Hypogonadal Men
Status: COMPLETED
Conditions: Hypogonadism|Primary Hypogonadism|Secondary Hypogonadism
Interventions: DRUG: Testosterone Undecanoate 750 mg|DRUG: Testosterone Undecanoate 1000 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TL011 in Severe, Active Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: TL011, anti CD20, for the treatment of rheumatoid arthritis|BIOLOGICAL: MabThera infusions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Potential for AZD5672 to Affect the Electrical Conduction Pathways in the Heart
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: AZD5672|DRUG: Moxifloxacin|DRUG: placebo|DRUG: AZD5672|DRUG: placebo|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Clinical Efficacy Between Dynamic Dip Screw and Cannulated Compression Screw for Fresh Femoral Neck Fracture
Status: COMPLETED
Conditions: Femoral Neck Fractures
Interventions: DEVICE: internal fixation implantation of dynamic hip screw|DEVICE: internal fixation implantation of cannulated compression screw
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a Novel Foot Offloading Device
Status: COMPLETED
Conditions: Plantar Fasciitis, Chronic|Heel Pain Syndrome|Fat Pad Syndrome
Interventions: DEVICE: PopSole™ Offloading Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Zanubrutinib, Rituximab and Combination Chemotherapy in Newly-diagnosed Aggressive B-cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: High Grade B-Cell Lymphoma, Not Otherwise Specified|High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements|Diffuse Large B Cell Lymphoma|B-cell Non Hodgkin Lymphoma|Mantle Cell Lymphoma
Interventions: DRUG: Zanubrutinib+R-CHOP; Zanubrutinib+R-DA-EPOCH; Zanubrutinib+R-HD MTX|DRUG: R-CHOP; R-DA-EPOCH; R-HD MTX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zanubrutinib Plus R-CHOP for Patients With Newly Diagnosed Untreated Non-GCB DLBCL
Status: RECRUITING
Conditions: Non-GCB/ABC Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Zanubrutinib|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Efficacy of YHD1044
Status: COMPLETED
Conditions: Premature Ejaculation
Interventions: DRUG: dapoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Qi Gong Training on Quality of Life in Patients With Systemic Lupus Erythematous (LuQi)
Status: COMPLETED
Conditions: Lupus Erythematosus, Systemic
Interventions: OTHER: Qi Gong
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Aripiprazole Oral Solution in the Treatment of Children and Adolescents With Autistic Disorder
Status: COMPLETED
Conditions: Autistic Disorder
Interventions: DRUG: Aripiprazole Oral Solution|DRUG: Placebo Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Developing and Implementing E-psychotherapy Program for Mental Health Challenges in Oncology and Palliative Care
Status: RECRUITING
Conditions: Mental Health Issue|Depression|Anxiety|Palliative Care|Oncology
Interventions: BEHAVIORAL: e-CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Dietary Factors on Physiological Subjective Stress Responses
Status: COMPLETED
Conditions: Chronic Stress
Interventions: DIETARY_SUPPLEMENT: Yogurt-like snacks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ticagrelor With Aspirin Dual Antiplatelet Therapy Combined With Intravenous Thrombolysis for Ischemic Stroke
Status: RECRUITING
Conditions: Ischemic Stroke, Acute
Interventions: DRUG: Early Dual Antiplatelet Therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Lung Ultrasound in Monitoring Fluid Resuscitation in Chest Trauma Patients
Status: COMPLETED
Conditions: Contusions Pulmonary|Lung Injury|Chest Trauma|Fluid Overload Pulmonary Edema
Interventions: OTHER: Chest examination with Ultrasound device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: eSET Plus Single Embryo Cryotransfer vs Double Embryo Transfer
Status: COMPLETED
Conditions: Infertility|Pregnancy, Multiple
Interventions: PROCEDURE: Elective single embryo transfer|PROCEDURE: Double embryo transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Study of the Bioavailability of Magnesium Administrated by Two ChronoMag Smart Tablet® 50 mg Versus Three Mag2® Tablets 100mg.
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Magnesium chloride (ChronoMag Smart Tablet®)|DRUG: Magnesium carbonate (Mag2® Tablet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vertebroplasty Compared With a Sham-procedure for Painful Acute Osteoporotic Vertebral Fractures
Status: COMPLETED
Conditions: Osteoporotic Fractures
Interventions: PROCEDURE: Percutaneous vertebroplasty|PROCEDURE: Lidocaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of ChulaCov19 BNA159 and ChulaCov19 BNA159.2 Vaccines as a Booster Dose in Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19, SARS CoV 2 Infection
Interventions: BIOLOGICAL: ChulaCov19 BNA159 vaccine (50 mcg)|BIOLOGICAL: Pfizer/BNT vaccine (30 mcg)|BIOLOGICAL: COMVIGEN (ChulaCov19 BNA159.2) vaccine (50 mcg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Splinting After Collagenase Injection
Status: COMPLETED
Conditions: Dupuytren Contracture|Dupuytren's Disease
Interventions: DRUG: Collagenase Clostridium Histolyticum 0.9 MG [Xiaflex]|COMBINATION_PRODUCT: Xiaflex + Hand-Based Custom Orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Door To Unloading With IMPELLA CP System in Acute Myocardial Infarction - Safety and Feasibility Study
Status: COMPLETED
Conditions: STEMI
Interventions: DEVICE: Impella unloading prior to PPCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Talc Instillation In Addition To Daily Drainage Through a Tunneled Pleural Catheter to Improve Rates of Outpatient Pleurodesis in Patients With Malignant Pleural Effusion
Status: TERMINATED
Conditions: Malignant Pleural Effusion
Interventions: DRUG: Talc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Dose Chemotherapy in Treating Patients Undergoing Stem Cell Transplant for Recurrent or Refractory Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|DRUG: carmustine|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: melphalan|PROCEDURE: autologous hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy|RADIATION: total-body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study To Investigate Effect Of A New Drug (PF-00446687) In Post-Menopausal Women Who Suffer From Sexual Dysfunction.
Status: COMPLETED
Conditions: Female Sexual Dysfunction
Interventions: DRUG: PF-00446687|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Neoadjuvant Toripalimab Combined With Temozolomide in Resectable Stage III Melanoma
Status: NOT_YET_RECRUITING
Conditions: Melanoma Stage III
Interventions: DRUG: Toripalimab combined with Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Modulation of Dyspeptic Symptom During Food Ingestion in Functional Dyspepsia Patients Cognitive Modulation
Status: COMPLETED
Conditions: Brain Imaging|Functional Dyspepsia|Food
Interventions: OTHER: Yogurt
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Alogliptin in Participants With Type 2 Diabetes in Japan
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Alogliptin|DRUG: Alogliptin|DRUG: Alogliptin|DRUG: Alogliptin|DRUG: Voglibose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thrombus Aspiration in Heavy Thrombus Burden Acute ST-elevation Myocardial Infarction
Status: SUSPENDED
Conditions: Coronary Artery Disease|Percutaneous Coronary Intervention|ST Elevation Myocardial Infarction
Interventions: PROCEDURE: Manual Thrombus Aspiration|PROCEDURE: Standard PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin Modulation of Startle Reactivity to Social Stimuli and Moral Decision Making
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Benefit of Self-monitoring of Anticoagulation Instrument
Status: COMPLETED
Conditions: Mechanical Prosthetic Heart Valve Implantation|Patient Self Monitoring of Oral Anticoagulent Therapy
Interventions: DEVICE: INRatio / Coaguchek XS|DEVICE: Conventional follow-up of anti-coagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Clinical Study to Determine the Effect of YM178 on the Pharmacokinetics of Warfarin in Healthy Subjects
Status: COMPLETED
Conditions: Overactive Bladder|Pharmacokinetics
Interventions: DRUG: warfarin|DRUG: YM178
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety of D-lactate Producing Probiotics
Status: COMPLETED
Conditions: Acidosis
Interventions: OTHER: Starter formula|OTHER: starter formula with D-lactate producing probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quillivant Oral Suspension (Quillivant XR) in the Treatment of Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Quillivant Oral Suspension XR|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Exposure Therapy in Agoraphobic Participants
Status: COMPLETED
Conditions: Panic Disorder|Agoraphobia
Interventions: BEHAVIORAL: Virtual Reality Exposure Therapy for agoraphobic participants|BEHAVIORAL: Standard exposure in vivo for agoraphobic participants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beneficial Effects of a Polyphenol Enriched Beverage on Type 2 Diabetes Prevention and on Cardiovascular Risk Profile of Men and Women With Insulin Resistance.
Status: COMPLETED
Conditions: Diabetes|Cardiovascular Disease
Interventions: OTHER: Uncontrolled nutritional intervention with a supplemental beverage|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Single Dose IV Hydrocortisone in Post Traumatic Stress Disorder (PTSD) Prevention
Status: UNKNOWN
Conditions: Post Traumatic Stress Disorder
Interventions: DRUG: Placebo|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vicriviroc in HIV-Treatment Experienced Subjects (Study P04889AM8)(COMPLETED)
Status: COMPLETED
Conditions: HIV Infections|Acquired Immunodeficiency Syndrome
Interventions: DRUG: Vicriviroc|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Factorial Trial of Antimicrobial Therapy and/or Catheter Change for Catheter Urinary Tract Infections.
Status: WITHDRAWN
Conditions: Urinary Tract Infections
Interventions: DRUG: Antimicrobial|DEVICE: Catheter change
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Staying Well Study: An Open Trial of Mindfulness-Based Cognitive Therapy for the Prevention of Perinatal Depression
Status: COMPLETED
Conditions: Pregnancy|Depression|Postpartum Depression
Interventions: BEHAVIORAL: MBCT-PD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sorafenib as Adjuvant Treatment in the Prevention Of Recurrence of Hepatocellular Carcinoma (STORM)
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Nexavar (Sorafenib, BAY43-9006)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Task-oriented Training for Patients With Pusher Syndrome
Status: NOT_YET_RECRUITING
Conditions: Pusher Syndrome
Interventions: PROCEDURE: experimental group: task-oriented training individualized by the gravity perception|PROCEDURE: control group: visual feedback treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Mediators of Physical Exercise and Carnosine Induced Effects in Patients With Preclinical and Early Stage Neurodegenerative Disease
Status: UNKNOWN
Conditions: Subjective Cognitive Impairment|Mild Cognitive Impairment|Parkinson Disease|Healthy Volunteers
Interventions: BEHAVIORAL: exercise|DIETARY_SUPPLEMENT: carnosine supplementation|BEHAVIORAL: stretching|DIETARY_SUPPLEMENT: supplementation with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Comparing Perioperative Stress Reduction vs. Standard of Care in Ovarian Cancer (PRESERVE)
Status: RECRUITING
Conditions: Ovarian Cancer|Ovarian Carcinoma|Stage II Ovary Cancer|Stage II Ovarian Cancer|Stage III Ovary Cancer|Stage III Ovarian Cancer|Stage IV Ovary Cancer|Stage IV Ovarian Cancer|Epithelial Ovarian Cancer|Fallopian Tube Cancer|Stage II Fallopian Tube Cancer|Stage III Fallopian Tube Cancer|Stage IV Fallopian Tube Cancer|Primary Peritoneal Carcinoma
Interventions: BEHAVIORAL: Mind-body resilience training|BEHAVIORAL: Music therapy|DRUG: Propranolol|DRUG: Etodolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Botulinum Toxin Type A Topical Gel for Lateral Canthal Lines
Status: COMPLETED
Conditions: Skin Aging
Interventions: BIOLOGICAL: Botulinum toxin type A|BIOLOGICAL: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diets in Symptom Relief and the Influence of Quality of Life in People With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: BEHAVIORAL: Low FODMAP diet|BEHAVIORAL: Conventional IBS diet group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Amygdala Retraining Program in Patients With Chronic Fatigue Syndrome, Chronic Fatigue and Fibromyalgia
Status: COMPLETED
Conditions: Chronic Fatigue Syndrome|Chronic Fatigue|Fibromyalgia
Interventions: BEHAVIORAL: Amygdala Retraining Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nurse-led Care Models in Swiss Nursing Homes: Improving Interprofessional Care for Better Resident Outcomes (INTERCARE)
Status: COMPLETED
Conditions: Hospitalisations
Interventions: OTHER: Implementation of a nurse-led model of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Preoperative Yoga and Meditation for Pediatric Idiopathic Scoliosis Surgery
Status: COMPLETED
Conditions: Juvenile and Adolescent Idiopathic Scoliosis
Interventions: OTHER: Yoga and Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A First-in-human, Dose Escalation and Dose Expansion Study of SAR445877 in Adult Participants With Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: SAR445877|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Granulocyte Colony-stimulating Factor for the Treatment of Recurrent Implantation Failure in IVF Patients
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: neupogen administration for women with recurrent IVF failure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Revascularization Versus Optimal Medical Therapy of Chronic Total Coronary Occlusions on Left Ventricular Ischemia Reduction
Status: RECRUITING
Conditions: Chronic Total Occlusion of Coronary Artery
Interventions: PROCEDURE: Percutaneous coronary intervention (PCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antithrombotic Therapy After Coronary Artery Bypass Grafting Combined With Coronary Endarterectomy
Status: RECRUITING
Conditions: Anticoagulation|Coronary Endarterectomy
Interventions: DRUG: Warfarin|DRUG: DAPT|OTHER: CE+CABG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Simplified Anti-Thrombotic Therapy for FFR
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: FFR|DRUG: Aspirin|DRUG: Clopidogrel|DRUG: Bivalirudin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Erlotinib Versus Oral Etoposide in Patients With Recurrent or Refractory Pediatric Ependymoma
Status: TERMINATED
Conditions: Recurrent or Refractory Pediatric Ependymoma
Interventions: DRUG: erlotinib|DRUG: etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Vorinostat in Combination With Etoposide in Pediatric Patients < 21 Years at Diagnosis With Refractory Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors|Relapsed/Refractory Sarcomas
Interventions: DRUG: Vorinostat and Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term Dual Anti Platelet Therapy in Patients With ACS Treated With the COMBO Dual-therapy Stent
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Treatment 90 days DAPT|DRUG: Treatment 360 days DAPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antenatal Micronutrient Supplementation and Infant Survival
Status: COMPLETED
Conditions: Infant Mortality|Preterm Birth|Low Birth Weight|Neonatal Mortality|Perinatal Mortality
Interventions: DIETARY_SUPPLEMENT: Iron (27 mg) - folic acid (600 ug)|DIETARY_SUPPLEMENT: Multiple micronutrient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Accuro and the Use of Real Time Ultra Sound With Acoustic Puncture Assisted Device to Confirm Epidural Space End Point
Status: UNKNOWN
Conditions: Two Different Techniques to Perform Epidural Using Ultrasound
Interventions: PROCEDURE: Accuro|PROCEDURE: APAD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Evaluating the Efficacy and Safety of Neihulizumab vs "Conventional Treatment" to Treat Sr-aGvHD
Status: WITHDRAWN
Conditions: Steroid-refractory aGvHD Subsequent to Allogeneic Hematopoietic Cell Transplantation
Interventions: BIOLOGICAL: Neihulizumab Treatment|BIOLOGICAL: Conventional Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combining Ipilimumab, Degarelix, and Radical Prostatectomy in Men With Newly Diagnosed Metastatic Castration Sensitive Prostate Cancer or Ipilimumab and Degarelix in Men With Biochemically Recurrent Castration Sensitive Prostate Cancer After Radical Prostatectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Castration Sensitive Prostate Cancer
Interventions: DRUG: Degarelix|DRUG: Ipilimumab|PROCEDURE: Radical Prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate or Delayed Provisionalization in Posterior Healed Sites
Status: COMPLETED
Conditions: Partial Edentulism
Interventions: PROCEDURE: Immediate provisionalization|PROCEDURE: Delayed provisionalization|DEVICE: NobelParallel CC implant|DEVICE: Dental crown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Effectiveness of ADX-N05 in the Treatment of Excessive Daytime Sleepiness
Status: COMPLETED
Conditions: Narcolepsy
Interventions: DRUG: ADX-N05|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sapropterin as a Treatment for Autistic Disorder
Status: COMPLETED
Conditions: Autistic Disorder
Interventions: DRUG: sapropterin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment With Botulinum Toxin Type A (BOTOX®) in Chinese Patients With Moderate to Severe Frown Lines
Status: COMPLETED
Conditions: Glabellar Rhytides
Interventions: BIOLOGICAL: botulinum toxin Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Confocal Laser Endomicroscopy VERification
Status: RECRUITING
Conditions: Lung Cancer|Lung Neoplasm Malignant|Carcinoma, Non-Small-Cell Lung|Neoplasm of Lung
Interventions: DEVICE: Neelde Based Confocal Laser Endomicroscopy|PROCEDURE: Conventional diagnostic bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intensive Versus Standard One Year Monitoring on Glycaemic Control After Initiating CSII in Children With DT1. DEEP Study
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1|Pediatric ALL
Interventions: BEHAVIORAL: Monitoring of the patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Potential Synergistic Effect of Combined Blood Flow Restriction Training and Betaine Supplementation on Skeletal Muscle
Status: COMPLETED
Conditions: Blood Flow Restriction Training|Betaine Supplementation
Interventions: DIETARY_SUPPLEMENT: Betaine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Alpelisib and Paclitaxel in PIK3CA-altered Gastric Cancer
Status: RECRUITING
Conditions: Solid Tumor|Stomach Cancer
Interventions: DRUG: Alpelisib|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga-PSMA PET/CT or PET/MRI in Evaluating Patients With Recurrent Prostate Cancer
Status: COMPLETED
Conditions: Recurrent Prostate Carcinoma
Interventions: PROCEDURE: Computed Tomography|DRUG: Gallium Ga 68-labeled PSMA Ligand Glu-urea-Lys(Ahx)|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Zerafil® (Omalizumab) in Participants With Uncontrolled Moderate to Severe Allergic Asthma
Status: COMPLETED
Conditions: Allergic Asthma|Uncontrolled Moderate to Severe
Interventions: BIOLOGICAL: Omalizumab (CinnaGen)|BIOLOGICAL: Omalizumab (Genentech, Inc., USA and Novartis Pharmaceuticals Corp, Switzerland)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Carvedilol Rapid Up-Titration in Patients With Heart Failure With Reduced Ejection Fraction
Status: UNKNOWN
Conditions: Heart Failure With Reduced Ejection Fraction HFrEF
Interventions: DRUG: Carvedilol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study to Evaluate KP405 in Healthy and Parkinson's Disease Patients
Status: NOT_YET_RECRUITING
Conditions: Safety Issues|Tolerance
Interventions: DRUG: KP405|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab Combining Bortezomib Versus Rituximab in Management of ITP
Status: UNKNOWN
Conditions: Immune Thrombocytopenia|Purpura, Thrombocytopenic, Idiopathic
Interventions: DRUG: Rituximab|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 506U78 in Treating Patients With Refractory Hematologic Cancer
Status: COMPLETED
Conditions: Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Lymphoblastic Lymphoma|T-cell Childhood Acute Lymphoblastic Leukemia
Interventions: DRUG: nelarabine|DRUG: methotrexate|DRUG: cytarabine|DRUG: therapeutic hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stretching the Posterior Capsule of the Shoulder in the Stability and the Throwing Performance in Handball Players
Status: COMPLETED
Conditions: Shoulder Injuries and Disorders
Interventions: OTHER: Experimental|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immunologic Determinants of Response to Pembrolizumab (MK-3475) in Advanced Melanoma (MK-3475-161/KEYNOTE-161)
Status: TERMINATED
Conditions: Advanced Melanoma
Interventions: BIOLOGICAL: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or Lymphomas
Status: COMPLETED
Conditions: Childhood Burkitt Lymphoma|Childhood Central Nervous System Germ Cell Tumor|Childhood Diffuse Large Cell Lymphoma|Childhood Grade III Lymphomatoid Granulomatosis|Childhood Immunoblastic Large Cell Lymphoma|Recurrent Childhood Brain Stem Glioma|Recurrent Childhood Cerebellar Astrocytoma|Recurrent Childhood Cerebral Astrocytoma|Recurrent Childhood Ependymoma|Recurrent Childhood Grade III Lymphomatoid Granulomatosis|Recurrent Childhood Large Cell Lymphoma|Recurrent Childhood Liver Cancer|Recurrent Childhood Lymphoblastic Lymphoma|Recurrent Childhood Malignant Germ Cell Tumor|Recurrent Childhood Medulloblastoma|Recurrent Childhood Rhabdomyosarcoma|Recurrent Childhood Small Noncleaved Cell Lymphoma|Recurrent Childhood Soft Tissue Sarcoma|Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor|Recurrent Childhood Visual Pathway Glioma|Recurrent Colon Cancer|Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Recurrent Melanoma|Recurrent Nasopharyngeal Cancer|Recurrent Neuroblastoma|Recurrent Osteosarcoma|Recurrent Wilms Tumor and Other Childhood Kidney Tumors|Recurrent/Refractory Childhood Hodgkin Lymphoma|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: irinotecan hydrochloride|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food Study of Valacyclovir Hydrochloride Tablets 1000 mg to Valtrex® Tablets 1000 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Valacyclovir Hydrochloride Tablets 1000 mg|DRUG: Valtrex® Tablets 1000 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of the ToFscan and TetraGraph During Recovery of Neuromuscular Function in the Post Anesthesia Care Unit
Status: COMPLETED
Conditions: Residual Neuromuscular Blockade
Interventions: DEVICE: TetraGraph (TG)|DEVICE: ToFscan (TS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety/PK Study of Gene Modified Donor T Cell Infusion in Children With Recurrent Hem Malignancies After Allo Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematologic Malignancy
Interventions: BIOLOGICAL: BPX-501 T cells|DRUG: rimiducid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Furosemide Treatment Before Blood Transfusion in Patients With Systolic Dysfunction
Status: WITHDRAWN
Conditions: Anemia Treatment Among Patients Suffering From Left Ventricular Systolic Dysfunction
Interventions: DRUG: furosemide|DRUG: placebo normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Italian Observation of Antiretroviral Treatment in Participants Taking Darunavir/ Cobicistat Plus Emtricitabine and Tenofovir Alafenamide Fumarate
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV)
Interventions: DRUG: D/C/F/TAF Fixed-Dose Combination (FDC)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BREATHE 5-OL: Tracleer (Bosentan) in Patients With Pulmonary Arterial Hypertension Related to Eisenmenger Physiology
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Tracleer®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Evaluate the Feasibility of Post-Hematopoietic Stem Cell Transplant Prophylaxis With Decitabine Combined With Filgrastim for Children and Young Adults With AML, MDS and Related Myeloid Malignancies
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes|Myeloid Malignancies|MDS|Inherited Bone Marrow Failure Syndrome|Myeloid Neoplasm|Aml
Interventions: DRUG: Decitabine|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of SPD485 in Children Aged 6-12 Diagnosed With ADHD
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Methylphenidate Transdermal System|DRUG: Placebo|DRUG: Concerta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ChonDux for Filling Full Thickness Cartilage Defects in the Femoral Condyle of the Knee
Status: TERMINATED
Conditions: Cartilage Defect
Interventions: DEVICE: ChonDux|DEVICE: ChonDux
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Tolerogenic Fibroblasts in Patients With Refractory Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting|Multiple Sclerosis
Interventions: BIOLOGICAL: Tolerogenic Fibroblasts
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acthar Gel in Participants With Pulmonary Sarcoidosis
Status: COMPLETED
Conditions: Sarcoidosis, Pulmonary
Interventions: DRUG: Acthar Gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate LB1148 for Return of Gastrointestinal Function and Adhesions in Subjects Undergoing Bowel Resection
Status: COMPLETED
Conditions: Ileus|Post-Operative Adhesions
Interventions: DRUG: LB1148|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Progressing Home Health Rehabilitation for Older Adults
Status: COMPLETED
Conditions: Older Adults|Physical Deconditioning
Interventions: BEHAVIORAL: Progressive Multi-Component (PMC)|BEHAVIORAL: Enhanced Usual Care (EUC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT