pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of TNFerade™ Biologic With 5-FU and Radiation Therapy for First-Line Treatment of Unresectable Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: GENETIC: TNFerade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 2-Chlorodeoxyadenosine and Cytarabine in Patients With Idiopathic Hypereosinophilic Syndrome (HES)
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: 2-CdA|DRUG: Ara-C|DRUG: G-CSF (Granulocyte colony-stimulating factor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Memantine Versus Donepezil in Early Stages of Alzheimer's Disease
Status: COMPLETED
Conditions: Dementia, Alzheimer Type
Interventions: DRUG: Memantine|DRUG: Donepezil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NBTXR3 and Radiation Therapy for the Treatment of Inoperable Recurrent Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Recurrent Lung Non-Small Cell Carcinoma|Stage I Lung Cancer AJCC v8|Stage IA1 Lung Cancer AJCC v8|Stage IA2 Lung Cancer AJCC v8|Stage IA3 Lung Cancer AJCC v8|Stage IB Lung Cancer AJCC v8|Stage II Lung Cancer AJCC v8|Stage IIA Lung Cancer AJCC v8|Stage IIB Lung Cancer AJCC v8|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Unresectable Lung Non-Small Cell Carcinoma
Interventions: OTHER: Hafnium Oxide-containing Nanoparticles NBTXR3|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy Study of Combination of Pembrolizumab and Lenalidomide, in Patients With Relapsed Non-Hodgkin and Hodgkin Lymphoma
Status: TERMINATED
Conditions: Relapsed Hodgkin Lymphoma|Relapsed Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial for Treating Painful Degenerative Disc Disease
Status: RECRUITING
Conditions: Degenerative Disc Disease
Interventions: BIOLOGICAL: Platelet-rich plasma (PRP), Platelet lysate (PL), and Platelet Poor Plasma (PPP)|OTHER: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Hypnosis in Reducing Pain and Other Side Effects in Women Undergoing Surgery for Breast Cancer
Status: COMPLETED
Conditions: Anxiety Disorder|Breast Cancer|Nausea and Vomiting|Pain
Interventions: OTHER: questionnaire administration|PROCEDURE: hypnotherapy|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Continuous Mobility Training in Prolonged Mechanical Ventilation
Status: COMPLETED
Conditions: Prolonged Mechanical Ventilation
Interventions: OTHER: Continuous Mobility Training|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Online Cognitive Training in PD, MS and Depressed Patients Treated With Electroconvulsive Therapy
Status: TERMINATED
Conditions: Idiopathic Parkinson's Disease|Multiple Sclerosis|Elderly Post Electric Convulsive Therapy
Interventions: BEHAVIORAL: Online cognitive training|BEHAVIORAL: Active control condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Combination Therapies in Lowering Blood Pressure in Black Africans
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Perindopril plus Amlodipine|DRUG: Perindopril plus Hydrochlorothiazide|DRUG: Amlodipine plus Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of HS-10353 in Participants With Postpartum Depression
Status: NOT_YET_RECRUITING
Conditions: Postpartum Depression
Interventions: DRUG: HS-10353 Capsules 30 mg, Oral, QN for 14 days|DRUG: HS-10353 Capsules 50 mg, Oral, QN for 14 days|DRUG: HS-10353 Capsules matching placebo, 30mg, Oral, QN for 14 days.|DRUG: HS-10353 Capsules matching placebo, 50mg, Oral, QN for 14 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NCCH2006/MK010 Trial (FORTUNE Trial)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced or Recurrent Solid Tumors|FGFR Gene Alterations
Interventions: DRUG: E7090
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine in Patients With Newly Diagnosed COVID-19 Compared to Standard of Care
Status: SUSPENDED
Conditions: COVID-19|Corona Virus Infection|SARS-CoV-2|2019-nCoV|2019 Novel Coronavirus
Interventions: DRUG: Hydroxychloroquine|DIETARY_SUPPLEMENT: Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Atazanavir and Nelfinavir, Each in Combination With 2 NRTIs, in Patients Who Have Failed Treatments Without a Protease Inhibitor
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: Atazanavir|DRUG: Nelfinavir mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of TLK199 HCl Liposomes for Injection in Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: TLK199 HCl Liposomes for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Combined Erector Spinae and Pecto-intercostal Fascial Plane Blocks Versus Thoracic Paravertebral Block in Perioperative Pain in Modified Radical Mastectomy
Status: COMPLETED
Conditions: Modified Radical Mastectomy
Interventions: DRUG: Bupivacaine Hydrochloride|DRUG: Dexamethasone phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chimeric Switch Receptor Modified T Cells for Patients With PD-L1+ Recurrent or Metastatic Malignant Tumors
Status: UNKNOWN
Conditions: Recurrent PD-L1+ Malignant Tumors|Metastatic PD-L1+ Malignant Tumors
Interventions: BIOLOGICAL: autologous CSR T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extended Delivery of Bupivacaine Study in Herniorrhaphy
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: Bupivacaine liposome injectable suspension|DRUG: Bupivacaine HCl without epinephrine via continuous infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Pharmacokinetics of and Effect on Systemic VEGF Levels in Age Related Macular Degeneration Patients
Status: UNKNOWN
Conditions: Age Related Macular Degeneration
Interventions: DRUG: Ranibizumab|DRUG: Bevacizumab|DRUG: Aflibercept|DRUG: Ranibizumab|DRUG: Bevacizumab|DRUG: Aflibercept|DRUG: Ranibizumab|DRUG: Bevacizumab|DRUG: Aflibercept|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prebiotics in the Prevention of Necrotizing Enterocolitis
Status: UNKNOWN
Conditions: Necrotizing Enterocolitis
Interventions: DIETARY_SUPPLEMENT: Galacto-oligosaccharide (GOS)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase Ib Study to Evaluate PRS-080 in Anemic Chronic Kidney Disease Patients
Status: UNKNOWN
Conditions: Anemia of Chronic Kidney Disease
Interventions: BIOLOGICAL: PRS-080#022-DP|BIOLOGICAL: PRS-080-Placebo#001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ability to Meet Enteral Nutritional Needs With a Peptide-based, High Protein Formula
Status: COMPLETED
Conditions: Enteral Feeding
Interventions: OTHER: Medical Food: Peptide-Based Enteral Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Stroke Volume Variation and Pleth Variability Index as Predictors of Fluid Responsiveness
Status: UNKNOWN
Conditions: Thyroidectomy|Fluid Responsiveness
Interventions: OTHER: HES 130/0.4 (VolulyteⓇ, Fresenius Kabi, Canada)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Somatosensory Assessment and Rehabilitation of Allodynia (SARA)
Status: COMPLETED
Conditions: Complex Regional Pain Syndrome|Peripheral Nerve Injuries|Hand Fractures
Interventions: OTHER: Somatosensory rehabilitation|OTHER: Usual treatment: physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Acceptability of Risk Stratification in the Fourth Trimester to Reduce Maternal Morbidity and Mortality
Status: COMPLETED
Conditions: Hypertensive Disorder of Pregnancy
Interventions: BEHAVIORAL: Remote blood pressure monitoring|DIAGNOSTIC_TEST: NT proBNP assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Effect of Topical Recombinant Human Vascular Endothelial Growth Factor for Induction of Healing of Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Foot Ulcer, Diabetic
Interventions: DRUG: placebo|DRUG: telbermin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Electroencephalographic Profiles During General Anesthesia: a Comparative Study of Remimazolam and Propofol
Status: UNKNOWN
Conditions: General Anesthesia|Electroencephalography|Laparoscopic Cholecystectomy|Remimazolam|Propofol
Interventions: DRUG: Remimazolam|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fecal Microbial Transplantation in Treatment of Irritable Bowel Syndrome; a Double Blinded Placebo Controlled Trial.
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: BIOLOGICAL: Fecal transplantation|OTHER: Placebo fecal transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dasotraline SEP360-105 Pediatric PK/PD Study
Status: COMPLETED
Conditions: Pediatric Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Dasotraline 1 mg, 2 mg, 4 mg, 8 mg, 12 mg, 16 mg, 20 mg, 24 mg, 28 mg, 32 mg once daily
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Retro-/Prospective, Non-interventional, Cohort Study in Adult Patients With Locally Advanced or Metastatic Tumors With a Neurotrophic Tyrosine Receptor Kinase (NTRK) Gene Fusion, Treated With Larotrectinib
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor, Adult|Locally Advanced Solid Tumor|Metastatic Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: POS vs FLU for First Line Treatment of Coccidioidomycosis (Study P04558Am1)(COMPLETED)
Status: COMPLETED
Conditions: Coccidioidomycosis
Interventions: DRUG: Posaconazole|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clofarabine and Low-Dose Total-Body Irradiation in Treating Patients With Acute Myeloid Leukemia Undergoing Donor Peripheral Blood Stem Cell Transplant
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Clofarabine|DRUG: Cyclosporine|OTHER: Laboratory Biomarker Analysis|DRUG: Mycophenolate Mofetil|PROCEDURE: Peripheral Blood Stem Cell Transplantation|OTHER: Pharmacological Study|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ISRT 20 Gy for Indolent Localized Gastrointestinal (GI)-Lymphoma
Status: RECRUITING
Conditions: Follicular Lymphoma (Gastric or Duodenal)|Marginal Zone Lymphoma (Gastric or Duodenal)
Interventions: RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Senolytics to Improve Osteoporosis Therapy
Status: RECRUITING
Conditions: Osteopenia, Osteoporosis
Interventions: DRUG: Dasatinib 100 Mg Oral Tablet|DIETARY_SUPPLEMENT: Quercetin 1.250 mg (oral)|DIETARY_SUPPLEMENT: Nicotinamide Riboside 1g (oral)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Moexipril HCl/Hydrochlorothiazide 15/25 mg Tablets Under Non-Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Moexipril HCl/hydrochlorothiazide 15/25 mg tablets|DRUG: UNIRETIC® 15/25 mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Perioperative Platelet Inhibition With Acetylsalicylic Acid in Patients With Resectable Tumors of the Pancreatic Head
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer Resectable
Interventions: DRUG: Acetylsalicylic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Internet-Based Cognitive Behavioral Therapy for Depressive Symptoms in Adolescents With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Depressive Symptoms
Interventions: BEHAVIORAL: CATCH-IT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor Lymphocyte Infusion (DLI) for Relapsed (Post Transplant) Leukemia
Status: COMPLETED
Conditions: Leukemia, Myeloid, Chronic|AML|MDS|Leukemia, Lymphocytic, Acute
Interventions: PROCEDURE: Donor Lymphocyte Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: mHealth to Improve Diet Quality Among Early Adolescents in SNAP-Ed in Hawaii
Status: RECRUITING
Conditions: Diet, Healthy
Interventions: BEHAVIORAL: HI-FLY Curriculum|BEHAVIORAL: HI-FLY Curriculum + PortionSize Ed app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Citrus Reticulate Unripe Fruit Extraction on Body Weight and Body Fat.
Status: RECRUITING
Conditions: Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: immature ponkan (Citrus reticulate) extract|DIETARY_SUPPLEMENT: placebo|BEHAVIORAL: time restricted feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ceritinib in Combination With Stereotactic Ablative Radiation Metastatic Lung Adenocarcinoma
Status: TERMINATED
Conditions: ALK-positive Non-small Cell Lung Cancer
Interventions: DRUG: Ceritinib|RADIATION: Stereotactic ablative body radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sildenafil for Chronic Obstructive Pulmonary Disease (COPD) Associated Pulmonary Hypertension
Status: WITHDRAWN
Conditions: COPD|Pulmonary Hypertension
Interventions: DRUG: sildenafil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Joint Hypermobility Syndrome on Delayed Onset of Muscle Soreness and Recovery Time
Status: UNKNOWN
Conditions: Hypermobility Syndrome
Interventions: OTHER: Eccentric Exercise for subjects with JHS|OTHER: Eccentric Exercise for Controls
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of SCT200 in Patients With Advanced Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: recombinant anti-EGFR monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TDF VS LAM + ADV in LAM + ADV Treated LAM-resistant CHB Patients With Undetectable Hepatitis B Virus DNA
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Lamivudine plus adefovir|DRUG: Tenofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study of NuCel® in Cervical Spine Fusion
Status: TERMINATED
Conditions: Spondylosis|Spinal Stenosis|Spondylolisthesis|Intervertebral Disc Disease|Intervertebral Disc Degeneration
Interventions: OTHER: NuCel with Allograft Bone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug Drug Interaction (DDI) Study of Pirtobrutinib (LOXO-305) and Different Formulations of Midazolam in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Midazolam Syrup|DRUG: Midazolam Solution|DRUG: Pirtobrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparison of Symbicort® pMDI 2 x 160/4.5 μg Bid and 2 x 80/4.5 μg Bid With Formoterol Turbuhaler® 2 x 4.5 μg Bid and Placebo in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Budesonide/formoterol pMDI|DRUG: Formoterol Turbuhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Tivozanib in Combination With Paclitaxel in Patients With Locally Recurrent or Metastatic Triple Negative Breast Cancer
Status: TERMINATED
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Tivozanib Hydrochloride|DRUG: paclitaxel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Interventions to Reduce Particulate Matter Exposure in Patients With COPD
Status: COMPLETED
Conditions: COPD
Interventions: BEHAVIORAL: Five active practices of living rules for responding to fine dust.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Symptoms Associated With Chemotherapy-Induced Peripheral Neuropathy
Status: RECRUITING
Conditions: Chemotherapy-induced Peripheral Neuropathy|Breast Cancer|Breast Cancer Female
Interventions: OTHER: European Organization for Research and Treatment of Cancer-Chemotherapy Induced Peripheral Neuropathy (EORTC-CIPN20) questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Frankincense Extract Gel on Non-Surgical Treatment of Chronic Periodontitis
Status: UNKNOWN
Conditions: Chronic Periodontitis
Interventions: PROCEDURE: scaling and root planing|PROCEDURE: Frankincense extract gel natural herbal product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Etomidate/Propofol Mixture or Propofol Monotherapy Use in Patients Undergoing General Anesthesia
Status: UNKNOWN
Conditions: Etomidate is Mixed With Propofol
Interventions: DRUG: Propofol 20 MG/ML|DRUG: Propofol 20 mg/ml , etomidate 2 mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Palliative Performance and Symptom Distress Scales in Older Patients With Advanced Ovarian Cancer
Status: TERMINATED
Conditions: Ovarian Cancer
Interventions: OTHER: Palliative Performance Scale version 2 (PPSv2)|OTHER: McCorkle Symptom Distress Scale (SDS)|OTHER: Geriatric Assessment|OTHER: Medical Records Abstraction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase II Study of Pertuzumab and Erlotinib for Metastatic or Unresectable Neuroendocrine Tumors
Status: TERMINATED
Conditions: Neuroendocrine Tumors|Carcinoid Tumors|Adrenal Gland Tumors|Neuroblastoma|Pancreatic Neuroendocrine Tumors|Multiple Endocrine Neoplasia
Interventions: DRUG: pertuzumab|DRUG: erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sirolimus in Children and Adolescents With Juvenile Nasopharyngeal Angiofibroma (JNA)
Status: RECRUITING
Conditions: Juvenile Nasopharyngeal Angiofibroma
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Taspoglutide Versus Placebo for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Plus Pioglitazone.
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: metformin|DRUG: pioglitazone|DRUG: placebo|DRUG: taspoglutide|DRUG: taspoglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Ketamine and Lithium Therapy in Bipolar Depression
Status: WITHDRAWN
Conditions: Bipolar Depression
Interventions: DRUG: Placebo|DRUG: Ketamine|DRUG: Ketamine/Lithium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Energy Drink Habituation Effects on Young Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Red Bull Energy Drink|DIETARY_SUPPLEMENT: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: AngioSafe Peripheral CTO Crossing System Study (RESTOR-1 Study)
Status: UNKNOWN
Conditions: Peripheral Artery Occlusion|Peripheral Arterial Disease
Interventions: DEVICE: AngioSafe Peripheral CTO Crossing System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Multicentre Study of the Safety and Efficacy Against COVID-19 of Nirmatrelvir/Ritonavir in the Adult Population
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: nirmatrelvir/ritonavir|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Herbal Nutraceutical Supplementation on Vasomotor Symptoms in Menopausal Women
Status: COMPLETED
Conditions: Vasomotor Symptoms|Postmenopausal Disorders
Interventions: DIETARY_SUPPLEMENT: JDS-HF 3.0|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation Prospectively the Level of Reduction in Cognitive Functions of Cancer Patients Who Are on Active Oncology Treatments and Use Cannabis. The Second Goal is to Identify High-risk Groups for Cognitive Impairment Due to Cannabis Use.
Status: COMPLETED
Conditions: 1- Cancer Patients During Chemotherapy Treatment|2- Use of Cannabis Comparing to Control Without Cannabis Use
Interventions: DRUG: cannabis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of HIFEM® Treatment of Urinary Incontinence in Women in Primary Care. A Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Urinary Incontinence|Quality of Life|Menopause|Mental Health Issue|Primary Health Care
Interventions: DEVICE: HIFEM- chair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of WM-A1-3389 in Participants With Advanced or Metastatic Solid Tumors and Non-Small Cell Lung Cancer (MK-3475-E90/KEYNOTE-E90)
Status: RECRUITING
Conditions: Advanced Solid Tumor|Metastatic Solid Tumor|Lung Cancer|Colorectal Cancer|Pancreatic Cancer|Cholangiocarcinoma|Head and Neck Cancer|Non Small Cell Lung Cancer
Interventions: BIOLOGICAL: WM-A1-3389|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Let-7a and miRNA-124 in Cases of Non-Hodgkin's Lymphoma and Acute Leukemia
Status: UNKNOWN
Conditions: Non Hodgkin Lymphoma and Acute Leukemia
Interventions: DIAGNOSTIC_TEST: real time pcr
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: One-year Clinical Evaluation of Bulk-fill Versus Conventional Incremental Posterior Restoration by FDI Criteria
Status: UNKNOWN
Conditions: Post Dental Restoration
Interventions: OTHER: bulk fill composite|OTHER: Nano resin composite (K Z350 xt)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: CoNCReTe-trial: Colles Fractures, Determining the Norm in Closed Reduction Techniques
Status: TERMINATED
Conditions: Colles' Fracture
Interventions: PROCEDURE: Manual Manipulation|PROCEDURE: Finger Trap Traction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of Physical Exercise at the Workplace (IRMA06) - Slaughterhouse Workers
Status: COMPLETED
Conditions: Musculoskeletal Disorders
Interventions: BEHAVIORAL: Strength training|BEHAVIORAL: Ergonomic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antihypertensive Efficacy and Safety of Candesartan/HCT 32/25 mg in Comparison With Individual Components and Placebo
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Candesartan cilexetil|DRUG: Hydrochlorothiazide|DRUG: Candesartan/HCT 32/25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Copeptin and Arterial Hypotension in Critically Ill Paediatric and Neonatal Intensive Care Patients
Status: COMPLETED
Conditions: Arterial Hypotension in Critically Ill Neonatal and Pediatric Patients
Interventions: DIAGNOSTIC_TEST: Copeptin in plasma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acetazolamide for the Prevention of High Altitude Illness: a Comparison of Dosing
Status: COMPLETED
Conditions: Prophylaxis of Acute Mountain Sickness
Interventions: DRUG: Low Dose Acetazolamide|DRUG: Normal Dose Acetazolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MORPHEE : Mechanisms of Cell Death Induced by Extracorporeal Photochemotherapy
Status: UNKNOWN
Conditions: Cutaneous T-Cell Lymphoma|Graft Vs Host Disease|Graft Rejection
Interventions: OTHER: Samples collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System
Status: RECRUITING
Conditions: Cancer|Cancer Central Nervous System|Cancer Thoracic|Cancer, Gastrointestinal|Cancer Gynecologic|Cancer, Genito-Urinary|Cancers Lymphatic|Cancer Head and Neck
Interventions: DEVICE: Registry - Observational
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Prostatic Tissue Concentration of Ertapenem After a Pre-operative Administration
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia (BPH) Requiring Surgical Resection
Interventions: DRUG: Ertapenem
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 3-year, Open-Label Study Evaluating Safety, Tolerability, and Efficacy of Lorecivivint in Subjects With Osteoarthritis of the Knee
Status: TERMINATED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Lorecivivint
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prostacyclin (PGI2) Pathway to Enhance Wound Healing in Diabetic Foot Ulcers
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Diabetic Foot
Interventions: DIAGNOSTIC_TEST: Microdialysis, current induced vasodilation|DIAGNOSTIC_TEST: Skin biopsy|DIAGNOSTIC_TEST: peri-ulcerated skin biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Inorganic Nitrate and eXercise Performance in Heart Failure (iNIX-HF)
Status: RECRUITING
Conditions: Heart Failure
Interventions: DRUG: KNO3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab Combination With SBRT and Concurrent Chemotherapy Treated Stage IV Oligometastatic Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer Metastatic
Interventions: DRUG: Camrelizumab|RADIATION: stereotactic body radiation therapy|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study to Assess Long-Term Safety and Tolerability of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: Xanomeline and Trospium Chloride Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Medication as a Potential Smoking Cessation Aid
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: DRUG: Levomilnacipran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A 12 Months Prospective Study Comparing Functional Outcome Scores in Hip Arthroscopic Labral Repair Versus Debridement
Status: RECRUITING
Conditions: Hip Injuries|Acetabular Labral Tear|Femoro Acetabular Impingement
Interventions: PROCEDURE: Arthroscopic Labral Repair|PROCEDURE: Arthroscopic Labral Debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Inflammation Reduction Trial - Inflammation Imaging Study
Status: COMPLETED
Conditions: Vascular Inflammation|Atherosclerotic Cardiovascular Disease
Interventions: DRUG: Low dose methotrexate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Integrated Distance Management Strategy for Patients With Cardiovascular Diseases in the Context of COVID-19
Status: UNKNOWN
Conditions: Angina Pectoris|Acute Coronary Syndrome|Coronary Syndrome|Coronary Artery Disease|Angioplasty|Stent Restenosis|Hypertension|Heart Failure, Systolic|Depression, Anxiety|Covid-19|Isolation, Social
Interventions: OTHER: Tele-medicine platform
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of a New Interface for NIV on Respiratory Drive
Status: UNKNOWN
Conditions: Acute Respiratory Failure
Interventions: DEVICE: High Flow Nasal Cannula (HFNC)|DEVICE: Continuous Positive Airway Pressure (CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Prognostic Biomarkers of Survival at 6 Months for Patients Treated With Bevacizumab Glioblastomas in First Relapse After Failure of Radiochemotherapy
Status: UNKNOWN
Conditions: Glioblastoma|Radiotherapy|Chemotherapy
Interventions: OTHER: Analysis of spectroscopic biomarkers of proliferation for six-month survival
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate Safety and Efficacy of Blanket Used to Prevent Anesthesia Induced Hypothermia
Status: COMPLETED
Conditions: Anesthesia Induced Hypothermia|Inadvertent Perioperative Hypothermia
Interventions: DEVICE: BARRIER® EasyWarm Active Self-Warming Blanket
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparative Study of Different Dosages of Vibrabot Capsule in the Treatment of Chronic Functional Constipation
Status: RECRUITING
Conditions: Chronic Functional Constipation
Interventions: DEVICE: Vibrabot capsules twice a week|DEVICE: Vibrabot capsules three times a week|DEVICE: Vibrabot capsules five times a week|DEVICE: Vibrabot capsules loading dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dairy and Non-Dairy Alternatives Comparative on Metabolic Outcomes
Status: COMPLETED
Conditions: Obesity|Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Dairy and plant-based dairy beverages and solids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy/Safety of Amlodipine Plus Losartan Versus Amlodipine in Patients With Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Amlodipine plus Losartan|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of MNI-672 SPECT for Detection/Exclusion of Cerebral B-amyloid in AD Subjects Compared to HVs.
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: [123I]MNI-672 SPECT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Effect of Praziquantel Treatment on Schistosoma Mansoni Morbidity and re-Infection Along Lake Victoria, Uganda
Status: COMPLETED
Conditions: Schistosomiasis|Malaria
Interventions: DRUG: praziquantel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CT Evaluating the Efficacy of Pre-incisional Local Analgesia With Ropivacaine + Dexamethasone in Pain Management After Tonsillectomy
Status: UNKNOWN
Conditions: Tonsillectomy
Interventions: DRUG: Oradexon|DRUG: Ropivacaine|DRUG: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Rimonabant for Treatment of Nonalcoholic Steatohepatitis (NASH) in Patients Without Diabetes
Status: TERMINATED
Conditions: Fatty Liver
Interventions: DRUG: Rimonabant|DRUG: Placebo (for Rimonabant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Assess the Influence of a Saw Palmetto Preparation in Patients With Benign Prostatic Hyperplasia (BPH) and Sexual Dysfunctions
Status: UNKNOWN
Conditions: Sexual Dysfunctions in Men With Benign Prostatic Hyperplasia
Interventions: DRUG: Saw palmetto berry extract
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ischaemic PReconditioning In Non Cardiac surgEry
Status: RECRUITING
Conditions: Myocardial Ischemia|Surgery
Interventions: OTHER: Remote ischemic preconditioning|OTHER: no ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Probiotics On Resistant Bacteria Colonization In Preterm Receiving Antibiotics
Status: COMPLETED
Conditions: Infant, Premature, Diseases
Interventions: DIETARY_SUPPLEMENT: Lactobacillus reuteri (biogai AB, Sweden)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Feasibility Study for Robotic Endomicroscopy to Better Define Resection Strategies (PERSEE)
Status: COMPLETED
Conditions: Cancer of Digestive System|Ovarian Cancer
Interventions: DEVICE: confocal laser endomicroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Peripheral Venous Catheter Insertion Using a Micro-guide in Neonatology
Status: RECRUITING
Conditions: Newborns|Neonatology|Intensive Care
Interventions: DEVICE: Insertion of peripheral venous catheter with micro-guide|OTHER: Classic insertion of peripheral venous catheter, without micro-guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety of Acamprosate for Alcohol Dependence in the Elderly: An Open-Label Study (SAFADIE)
Status: WITHDRAWN
Conditions: Alcohol Dependence
Interventions: DRUG: Acamprosate (Campral)|DRUG: Acamprosate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Impact of Donor Milk Pasteurized by HTST Treatment in Preterm Infants
Status: COMPLETED
Conditions: Late-Onset Neonatal Sepsis
Interventions: OTHER: donor milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mindfulness-based Social Work and Self-Care (MBSWSC)
Status: COMPLETED
Conditions: Stress|Burnout, Professional|Anxiety|Depression|Wellbeing
Interventions: BEHAVIORAL: MBSWSC|BEHAVIORAL: MBSC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioequivalence Study of Tretinoin Gel 0.05% to Brand Tretinoin Gel
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: Tretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Animal and Plant Proteins and Glucose Metabolism
Status: RECRUITING
Conditions: Metabolic Syndrome|Metabolic Syndrome, Protection Against|Glucose Metabolism Disorders
Interventions: OTHER: High animal protein isolate|OTHER: High animal protein whole food|OTHER: High plant protein isolate|OTHER: High plant protein whole food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of Glaucoma or Ocular Hypertension in Patients Within the United States
Status: COMPLETED
Conditions: Ocular Hypertension|Glaucoma
Interventions: DRUG: latanoprost 0.005%|DRUG: fixed combination latanoprost-timolol|DRUG: timolol 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioimpedance Analysis for Hemodialysis
Status: NOT_YET_RECRUITING
Conditions: Hemodialysis Complication
Interventions: DEVICE: Bioimpedance|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Controlled Trial Evaluating Avacopan in C3 Glomerulopathy
Status: COMPLETED
Conditions: C3 Glomerulopathy (C3G)
Interventions: DRUG: Avacopan|DRUG: Avacopan Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Total Neoadjuvant Therapy With Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Ultra Low Rectal Adenocarcinoma
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: DRUG: Envafolimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Venous Thrombotic Biological Profile of Different PCOS Phenotypes: French Cross-sectional Study
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome
Interventions: DIAGNOSTIC_TEST: Thrombotic profile
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Allogeneic Stem Cell Transplantation in Chronic Myeloid Leukemia Failing TKIs Therapy
Status: COMPLETED
Conditions: Leukemia|Myelogenous|Chronic|BCR-ABL Positive
Interventions: DRUG: Bosutinib|PROCEDURE: Bone Marrow Transplant|DRUG: Bone Marrow cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decitabine Followed by Donor Lymphocyte Infusion for Patients With Relapsed Acute Myeloblastic Leukemia(AML) After Allogeneic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Recurrent Adult Acute Myeloid Leukemia
Interventions: DRUG: Deciatbine(DAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UNIVERSAL 1: Pharmacokinetic Study of a Novel DTG/FTC/TAF Dose Ratio for Children
Status: NOT_YET_RECRUITING
Conditions: HIV Infection
Interventions: DRUG: dolutegravir (DTG)/emtricitabine (FTC)/tenofovir alafenamide (TAF) regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Microfragmented Adipose Tissue Loaded on Bovine Graft Versus Bovine Graft Only on Ridge Preservation.
Status: NOT_YET_RECRUITING
Conditions: Tooth Mobility
Interventions: PROCEDURE: microfragmented adipose tissue loaded on bovine graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunomodulation to Optimize Vascularized Composite Allograft Integration for Limb Loss Therapy
Status: RECRUITING
Conditions: Immunosuppression
Interventions: DRUG: Belatacept|PROCEDURE: Hand transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determine if Either of 2 Doses of Study Drug Given With a Low-dose of Cyclophosphamide After a Complete or Partial Response to a Platinum-based Second-line Therapy in Women With Recurrent Ovarian Carcinoma Results in a Longer Time to Progression When Compared to the First Time to Progression.
Status: WITHDRAWN
Conditions: Ovarian Cancer
Interventions: DRUG: Tucotuzumab celmoleukin (EMD 273066)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine if Atorvastatin Reduces Size and Stiffness of Muscle in the Left Ventricle of the Heart
Status: COMPLETED
Conditions: Hypertrophic Cardiomyopathy
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Elastography (MRE) as a Predictor of HCC Recurrence After Radiofrequency Ablation (RFA)
Status: COMPLETED
Conditions: Hepatic Fibrosis|Hepatocellular Carcinoma
Interventions: PROCEDURE: Magnetic resonance elastography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC