pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of Endoscopic Radiofrequency Ablation Versus Photodynamic Therapy for Inoperable Cholangiocarcinoma
Status: UNKNOWN
Conditions: Cholangiocarcinoma
Interventions: PROCEDURE: Self expanding metallic stent (SEMS)|PROCEDURE: Endoscopic radiofrequency ablation (ERFA)|PROCEDURE: Photodynamic therapy (PDT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serial Brain MRI in Hospitalized Preterm Infants
Status: RECRUITING
Conditions: Preterm Birth Complication
Interventions: BEHAVIORAL: SENSE-plus: The Supporting and Enhancing NICU Sensory Experiences 2nd Edition (SENSE II) program|BEHAVIORAL: SENSE: The Supporting and Enhancing NICU Sensory Experiences 2nd Edition (SENSE II) program|OTHER: Reference/ Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Current Treatment Outcomes in Japanese RCC Patients Treated With Avelumab Plus Axitinib as First-line Therapy: Retrospective Study (J-DART)
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: avelumab|DRUG: axitinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Laser Laryngeal Surgery
Status: COMPLETED
Conditions: Otorhinolaryngologic Surgical Procedures|Laser Therapy
Interventions: DEVICE: THRIVE|DEVICE: Endotracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Intrasaccular neCk Occlusion deVice Treatment of Intracranial Aneurysm in Acute Subarachnoid hemorRhAGE
Status: UNKNOWN
Conditions: Subarachnoid Hemorrhage|Subarachnoid Hemorrhage, Aneurysmal
Interventions: DEVICE: Neqstent or Contour
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of the Safety and Effectiveness of a Trifocal IOL
Status: ACTIVE_NOT_RECRUITING
Conditions: Eye Diseases|Postcataract Aphakia|Cataract|Lens Opacities
Interventions: DEVICE: FINEVISION HP IOL|DEVICE: Alcon AcrySof SN60AT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of a Clinical Pathway for Pelvic Fragility Fractures
Status: RECRUITING
Conditions: Pelvic Bone Injury|Sacral Fracture|Pelvic Fracture|Fragility Fracture
Interventions: OTHER: Clinical pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Refractory Systemic Lupus Erythematosus by Allogeneic Mesenchymal Stem Cells Derived From the Umbilical Cord
Status: UNKNOWN
Conditions: Lupus Erythematosus|Stem Cell Transplant
Interventions: BIOLOGICAL: mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bovine Colostrum as a Fortifier Added to Human Milk for Preterm Infants
Status: COMPLETED
Conditions: Growth|Necrotizing Enterocolitis|Late-Onset Sepsis|Feeding Intolerance
Interventions: DIETARY_SUPPLEMENT: Bovine Colostrum (BC) / intervention group|DIETARY_SUPPLEMENT: FM85 / control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Antioxidants and B Vitamins Supplements on Inflammation in Obese Diabetic Patients
Status: COMPLETED
Conditions: Diabetes|Obesity
Interventions: DIETARY_SUPPLEMENT: vitamins|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: S-adenosylmethionine (SAMe) in Patients With Primary Sclerosing Cholangitis (PSC)
Status: RECRUITING
Conditions: Primary Sclerosing Cholangitis (PSC)
Interventions: DIETARY_SUPPLEMENT: S-Adenosyl-L-methionine (SAMe)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Lavage vs Serial Needle Aspiration for Infected Joints
Status: WITHDRAWN
Conditions: Arthritis|Septic
Interventions: PROCEDURE: Surgical Lavage (Arthrotomy)|PROCEDURE: Arthrocentesis (Serial needle aspiration)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Modified Lateral Lumbar Interbody Fusion VS. Transforaminal Lumbar Interbody Fusion for Adult Degenerative Scoliosis
Status: UNKNOWN
Conditions: Degenerative Scoliosis|Minimally Invasive|Spinal Deformity
Interventions: PROCEDURE: Modified lateral lumbar interbody fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of 7-Valent Pneumococcal Conjugate Vaccine in Children Receiving Solid Organ Transplants
Status: COMPLETED
Conditions: Organ Transplant|Immunosuppression
Interventions: BIOLOGICAL: 7-valent pneumococcal conjugate vaccine|BIOLOGICAL: Pneumococcal 7-valent Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency Study of Traditional Chinese Medicine (TCM) Versus Western Medicine (WM) on Ischemic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: acupuncture, massage and basic TCM treatment|OTHER: rehabilitation and WM basic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial About Treatment of Mild to Moderate Persistent Alergic Rhinnitis With Test or Reference Mometasone (PUMA)
Status: COMPLETED
Conditions: Mild to Moderate Persistent Allergic Rhinitis
Interventions: DRUG: Mometasone furoate|DRUG: Mometasone furoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utility of a Supraaponeurotic Mesh as Prophylaxis of the Midline Eventration After an Oncological Colorrectal Resection
Status: UNKNOWN
Conditions: Eventration
Interventions: DEVICE: DynaMesh®-CICAT longitudinal measure 10x35 cm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Blood Pressure During ESD is Related With the Postoperative Bleeding
Status: UNKNOWN
Conditions: Gastrointestinal Disease|Gastrointestinal Bleeding
Interventions: DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of a Practice-oriented Recovery Program for Female Endurance Athletes With Relative Energy Deficiency
Status: COMPLETED
Conditions: Relative Energy Deficiency in Sport
Interventions: BEHAVIORAL: Nutritional behavioral intervention|BEHAVIORAL: Nutritional behavioral intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Sutureless Vs. Standard Biological Prostheses for Surgical Aortic Valve Replacement
Status: UNKNOWN
Conditions: Heart Valve Prosthesis|Aortic Stenosis|Hemodynamics
Interventions: DEVICE: Sutureless aortic bioprosthesis|DEVICE: Conventional stented sutured aortic prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nab-PTX, Ifosfamide and Cisplatin in the Treatment of Pediatric Extracranial Germ Cell Tumor.
Status: UNKNOWN
Conditions: Extracranial Germ Cell Tumor, Pediatric
Interventions: DRUG: albumin-bound paclitaxel (nab-PTX), ifosfamide and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PPIO-007 Correlation Analysis of Type II Diabetes Mellitus on Short-term and Long-term Outcomes of Patients With Esophageal Squamous Cell Cancer Undergoing Minimally Invasive Esophagectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma|Surgery
Interventions: OTHER: Whether there is type 2 diabetes mellitus before surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults
Status: RECRUITING
Conditions: B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
Interventions: PROCEDURE: Biospecimen Collection|BIOLOGICAL: Blinatumomab|PROCEDURE: Bone Marrow Aspiration and Biopsy|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Dasatinib|DRUG: Dexamethasone|DRUG: Doxorubicin Hydrochloride|PROCEDURE: Echocardiography|PROCEDURE: Electrocardiography|PROCEDURE: Lumbar Puncture|DRUG: Mesna|DRUG: Methotrexate|PROCEDURE: Multigated Acquisition Scan|DRUG: Ponatinib Hydrochloride|DRUG: Prednisone|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Mental Health at Work Among Hospital Professionals
Status: RECRUITING
Conditions: Mental Health Issue
Interventions: OTHER: Information session on mindfulness meditation and questionnaires|DEVICE: Mindfulness meditation experimentation, practice program, questionnaires, individual interview and focus group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Costs and Effects of Three Modes for Disease Management of Chronic Obstructive Pulmonary Disease in General Practice
Status: COMPLETED
Conditions: Lung Diseases, Obstructive
Interventions: BEHAVIORAL: an integrated self-management education program|BEHAVIORAL: regular practice nurse review (monitoring controls)|BEHAVIORAL: care at initiative of the patient (usual GP care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Balugrastim (Neugranin) in Breast Cancer Participants Receiving Doxorubicin/Docetaxel
Status: COMPLETED
Conditions: Chemotherapy-induced Neutropenia
Interventions: BIOLOGICAL: Balugrastim|DRUG: Pegfilgrastim|DRUG: Chemotherapy Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Veliparib in Treating Patients With Persistent or Recurrent Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: BRCA1 Mutation Carrier|BRCA2 Mutation Carrier|Ovarian Epithelial Tumor|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine Efficacy and Safety of Inhaled AeroLEF in the Treatment of Acute Post-op Pain in Adult Patients Undergoing Elective Orthopedic Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: AeroLEF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Hypotension Prediction Index for Blood Pressure Management
Status: COMPLETED
Conditions: Intraoperative Hypotension
Interventions: DEVICE: Acumen HPI-enabled EV1000 screen|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Efficacy and Safety of FB825 in Adult With Allergic Asthma
Status: RECRUITING
Conditions: Allergic Asthma
Interventions: BIOLOGICAL: FB825|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Uterotonic Prophylaxis Trial
Status: COMPLETED
Conditions: Hemorrhage
Interventions: DRUG: Methergine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Renal Blood Flow During Human Endotoxemia
Status: UNKNOWN
Conditions: Healthy|Type 2 Diabetes|Endotoxemia
Interventions: DRUG: Escherichia Coli Endotoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Checkpoint Blockade Immunotherapy Combined With Stereotactic Body Radiation in Advanced Metastatic Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Cancer
Interventions: DRUG: Checkpoint blockade immunotherapy|RADIATION: Checkpoint blockade immunotherapy plus SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Subcutaneous (SC) Bortezomib, Lenalidomide and Dexamethasone for Relapsed and/or Refractory Multiple Myeloma; Followed by SC Bortezomib Maintenance
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Wii Fit Rehabilitation in Patients With Chronic Ankle Instability a Randomized Control Study
Status: RECRUITING
Conditions: Instability, Joint
Interventions: DEVICE: Wii fit|OTHER: Strengthening, proprioceptive exercises.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Trial of WHT vs. PC-GE to Promote Non-Pharmacological Strategies to Treat Chronic Pain in Veterans
Status: UNKNOWN
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Whole Health Team (WHT) Intervention Arm, Primary Care Group Education (PC-GE) Intervention Arm, Usual Primary Care (UPC) Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Hybrid Effectiveness Implementation Trial Evaluating Behavioral Treatments for Insomnia for Socioeconomically Disadvantaged Adults in Primary Care
Status: RECRUITING
Conditions: Insomnia
Interventions: BEHAVIORAL: Tele-Brief Behavioral Treatment for Insomnia|BEHAVIORAL: Tele-Cognitive-Behavioral Therapy for Insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of ADL5859 in Participants With Neuropathic Pain Associated With Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Peripheral Neuropathy|Neuropathic Pain
Interventions: DRUG: ADL5859|DRUG: Duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Interferon Alpha Citizen by Sub-Lingual Way on the Humoral Immunizing Answer
Status: TERMINATED
Conditions: Influenza Infection
Interventions: DRUG: vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Sugammadex and Conventional Reversal on Lung Function in Laparoscopic Abdominal Surgery
Status: RECRUITING
Conditions: Atelectasis, Postoperative|Pulmonary Function; Newborn, Abnormal
Interventions: DRUG: Sugammadex|DRUG: Neostigmine and atropine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effects of Dabrafenib on the Single Dose Pharmacokinetics (PK) of Rosuvastatin and Midazolam
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Rosuvastatin10 mg tablet|DRUG: Midazolam 3 mg syrup|DRUG: Dabrafenib 75 mg capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sulforaphane in Broccoli Sprouts on Nrf2 Activation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DIETARY_SUPPLEMENT: Broccoli sprouts
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects On Dihydrotestosterone Regulated Gene Expression In Benign Prostatic Hyperplasia Or Prostate Cancer
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia|Prostate Cancer
Interventions: DRUG: Dutasteride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Doxycycline/UrsoDeoxyCholicAcid on Disease Progression in ATTR Amyloidosis
Status: COMPLETED
Conditions: Transthyretin Amyloidosis|Cardiomyopathy
Interventions: DRUG: Doxycycline|DRUG: Ursodeoxycholic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PAIN: A Project Assessing the Impact of a Novel Cannabinoid Product
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain
Interventions: DRUG: Cannabidiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Patient Derived Vascularized MicroTumor Model of Gastrointestinal Peritoneal Carcinomatosis
Status: RECRUITING
Conditions: Peritoneal Carcinomatosis|Gastrointestinal Peritoneal Carcinomatosis
Interventions: OTHER: Biospecimen Collection (Blood, Ascites/Peritoneal Wash Fluid and/or Tumor Samples)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Full Versus Fractional Dose of COVID-19 Vaccine Given as a Booster for the Prevention of COVID-19 in Adults in Mongolia.
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: Tozinameran - Standard Dose|BIOLOGICAL: Tozinameran - Fractional Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Methylene Blue and Postoperative Neurocognitive Disorders
Status: COMPLETED
Conditions: Postoperative Delirium|Postoperative Cognitive Dysfunction
Interventions: DRUG: Methylene Blue|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Galvus on Met Phase 4 Study : Study to Evaluate the Efficacy and Safety of Early Combination of Vildagliptin and Metformin in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: vildagliptin 50 mg bid plus metformin 1500mg (Galvus+Diabex)|DRUG: metformin 1500mg plus metformin 500mg or 1000mg (Diabex)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF)
Status: RECRUITING
Conditions: Ileal Pouch
Interventions: BIOLOGICAL: EXE-346|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Femoral Neck-shaft Angle in Sohag Population
Status: UNKNOWN
Conditions: Hip Abnormalities|Femur; Angulation|Urinary Stone|Lower Limb Arterial Embolus
Interventions: OTHER: Screening in picture archiving and communication system (PACS) .
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Irinotecan Plus Cisplatin vs Pemetrexed Plus Cisplatin as 2nd Line in NSCLC Stage IIIB/IV
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Irinotecan|DRUG: Cisplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2B Micronized DHACM vs. Saline in the Treatment of Knee Osteoarthritis
Status: TERMINATED
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Micronized DHACM 40 mg|BIOLOGICAL: Micronized DHACM 100 mg|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of FCSEMS and Plastic Stents
Status: COMPLETED
Conditions: Infected Pancreatic Necrosis|Acute Pancreatic Fluid Collection|Pancreatic and Peripancreatic Necrosis|Pancreatic Collection|Symptomatic Pancreatic Necrosis
Interventions: DEVICE: FCSEM Stent|DEVICE: Plastic Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transdermal Estrogen in Older Premenopausal Women With Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa|Osteoporosis
Interventions: DRUG: estradiol 0.045 mg/levonorgestrel 0.015mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous v Bolus Infusion of Cefazolin During Ventral Hernia Repair
Status: WITHDRAWN
Conditions: Surgical Site Infections
Interventions: PROCEDURE: Bolus infusion of Cefazolin|PROCEDURE: Continuous infusion of Cefazolin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics and Drug Interaction Study Between Rosuvastatin and Fenofibric Acid in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cresto 20mg|DRUG: Fenofibric acid 135mg|DRUG: Cresto 20mg, Fenofibric acid 135mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Tear Film Break-up Time After Instillation of Artificial Tears
Status: COMPLETED
Conditions: Keratoconjunctivitis Sicca
Interventions: DRUG: glycerin|DRUG: polyethylene glycol 400/propylene glycol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Different Dosing Schedules of GlaxoSmithkline (GSK) Biologicals' Herpes Zoster (HZ) Vaccine in Adults 50 Years of Age or Older
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Herpes zoster vaccine GSK1437173A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Safety and Tolerability of LB-P6 and LB-P8 in Healthy Participants
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Non-Alcoholic Steatohepatitis
Interventions: DRUG: LB-P6|DRUG: LB-P8|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine and IV Acetaminophen for the Prevention of Postoperative Delirium Following Cardiac Surgery
Status: COMPLETED
Conditions: Delirium
Interventions: DRUG: IV acetaminophen & IV propofol|DRUG: IV acetaminophen & IV dexmedetomidine|DRUG: IV propofol & placebo|DRUG: IV dexmedetomidine & placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicentre Randomised Clinical Trial of Laser Treatment Plus Intravitreal Triamcinolone for Diabetic Macular Oedema
Status: COMPLETED
Conditions: Diabetic Macular Oedema
Interventions: DRUG: Triamcinolone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study Investigating Everolimus and Dovitinib in Metastatic Clear Cell Renal Cancer
Status: COMPLETED
Conditions: Metastatic Clear Cell Renal Cancer
Interventions: DRUG: Dovitinib|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of Safety and ex Vivo Fluorescence of BLZ-100 in Adult Subjects With Solid Tumors Undergoing Surgery
Status: COMPLETED
Conditions: Tumors, Breast
Interventions: DRUG: BLZ-100
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Open Label, Multi Centre Phase IV Study of Adefovir Dipivoxil in Korean Patients With Chronic Hepatitis B (CHB)
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Adefor dipivoxil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selected De-escalation Radiotherapy for Postoperative Head and Neck Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Head and Neck Squamous Cell Carcinoma|Radiotherapy|Immunotherapy|Surgery
Interventions: COMBINATION_PRODUCT: induction therapy; surgery; radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-surgical Treatment of Peri-implant Mucositis
Status: COMPLETED
Conditions: Peri-implant Mucositis
Interventions: DRUG: Chlorhexidine|DEVICE: Air-powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inherited Cancer Early Diagnosis (ICED) Study
Status: RECRUITING
Conditions: Li Fraumeni Syndrome|Lynch Syndrome|Hereditary Diffuse Gastric Cancer|Cowden Syndrome|Peutz-Jeghers Syndrome|Familial Adenomatous Polyposis|SMAD4 Gene Mutation|MutYH-associated Polyposis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioequivalence Study of Ondansetron Tablets USP 8 mg Under Fed Condition
Status: COMPLETED
Conditions: Fed
Interventions: DRUG: Ondansetron Tablets USP 8 mg|DRUG: Ondansetron Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Empagliflozin in Patients With Refractory Diabetes Mellitus With Insulin Resistance
Status: UNKNOWN
Conditions: Insulin Resistance - Type A|Insulin Resistance - Type B|Lipoatrophic Diabetes Mellitus|Insulin Resistance Syndrome
Interventions: DRUG: Empagliflozin Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Dark Chocolate in Achalasia Patients
Status: UNKNOWN
Conditions: Achalasia
Interventions: DIETARY_SUPPLEMENT: dark chocolate|DIETARY_SUPPLEMENT: placebo chocolate with crossover to dark chocolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Iomab-B vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Leukemia, Acute Myeloid|Myeloid Leukemia, Acute|Leukemia, Myeloid, Acute|Acute Myelogenous Leukemia|Leukemia, Acute Myelogenous|Myelogenous Leukemia, Acute|AML|Bone Marrow Transplant
Interventions: DRUG: Iomab-B|DRUG: Conventional Care|PROCEDURE: HCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare 2 Botulinum Type A Toxins in the Treatment of Glabellar Frown Lines
Status: COMPLETED
Conditions: Frown Lines
Interventions: BIOLOGICAL: Botulinum toxin A "BoNT/A-DP"|BIOLOGICAL: Botulinum toxin A "Botox Cosmetics"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Long-term Safety of Oral Ozanimod in Chinese Participants With Moderately to Severely Active Ulcerative Colitis (UC)
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Ozanimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Cesamet™ for the Treatment of Pain in Patients With Chemotherapy-Induced Neuropathy
Status: COMPLETED
Conditions: Peripheral Neuropathy|Antineoplastic Combined Chemotherapy Protocols
Interventions: DRUG: Cesamet™ (nabilone)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Gastric Balloon in Morbid Obesity: Prospective Study
Status: UNKNOWN
Conditions: Morbid Obesity
Interventions: DEVICE: BMI more than 45 BMI|DEVICE: BMI less than 45 BMI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics in Subjects With Renal Impairment
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: cilengitide 2000mg|DRUG: cilengitide 2000mg|DRUG: cilengitide 2000mg|DRUG: cilengitide 1000mg|DRUG: cilengitide > 1000mg and up to 2000mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Dexmedetomidine and Laparoscopic Surgery
Status: COMPLETED
Conditions: Anesthesia Complication
Interventions: DRUG: Normal saline|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Detecting Metastases by PyL PET/CT in Subjects Starting Enzalutamide for Untreated Castration Resistant Prostate Cancer.
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Enzalutamide capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Transcutaneous Neuromodulation of the Post-tibial Nerve for Solifenacin 10 mg. Hyperactive Bladder Syndrome
Status: UNKNOWN
Conditions: Urinary Incontinence
Interventions: DRUG: Solifenacin Succinate|DEVICE: Neuro-Muscular Stimulators (NMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Southwest Hub for American Indian Youth Suicide Prevention Research
Status: RECRUITING
Conditions: Suicide|Surveillance|Mental Health|Substance Use|Depressive Symptoms
Interventions: BEHAVIORAL: New Hope (NH)|BEHAVIORAL: Elders Resilience (ER)|OTHER: Case Management (CM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Skin Cooling in Reducing Pain Associated With Non-invasive Treatments of Neurofibromatosis Type 1 Cutaneous Neurofibromas
Status: RECRUITING
Conditions: Neurofibromatosis 1
Interventions: DRUG: Deoxycholic Acid|DRUG: Polidocanol|DEVICE: 1064nm Nd:YAG laser|DEVICE: 755nm Alexandrite Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy & Safety of Nasal Influenza Immunisation in Children
Status: COMPLETED
Conditions: Influenza Vaccines Efficacy and Safety
Interventions: DRUG: Live attenuated influenza vaccine|PROCEDURE: Surveillance (nasal swabbing) during influenza season
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Oliceridine Analgesia on Postoperative Nause and Vomiting
Status: NOT_YET_RECRUITING
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Oliceridine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Endoscopic Large Caliber Drainage vs. Complete Necrosectomy for Treatment of Walled-off Pancreatic Necrosis
Status: WITHDRAWN
Conditions: Necrotizing Pancreatitis
Interventions: DEVICE: Double Pigtail Plastic Stent|DEVICE: AXIOS Metal Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Active Pregnancy Against COVID-19
Status: UNKNOWN
Conditions: Pregnancy Complications|Pregnancy, High Risk|Pregnancy Induced Hypertension|Newborn Morbidity|Fetal Growth Retardation|Fetus Disorder|Weight Gain, Maternal|Maternal-Fetal Relations
Interventions: OTHER: Exercise program|OTHER: Healthy lifestyle advise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Feel Breathe, Restriction Device Ventilatory Nasal (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Exercie oronasal breathing (ONB)|DEVICE: Exercie nasal breathing through the FB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Mini and Macro-esthetics Following En- Masse Retraction Versus Two Step Retraction
Status: UNKNOWN
Conditions: Bimaxillary Protrusion
Interventions: PROCEDURE: En-masse retraction|PROCEDURE: Two step Retraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcomes for Anesthesiologist-Led Care of Analgesic Protocol in Anorectal Surgery
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain
Interventions: DRUG: Multi-modal analgesia for Anes. Group|DRUG: Multi-modal analgesia for Surg. Group|PROCEDURE: Multi-modal analgesia during the surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders
Status: RECRUITING
Conditions: Periodic Fever, Aphthous Stomatitis, Pharyngitis, And Cervical Adenitis (Pfapa)|Obstructive Sleep Apnea|Tonsillitis|Tonsil Disorder|Sleep Disordered Breathing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1/2 Trial of ADI-270 in ccRCC
Status: NOT_YET_RECRUITING
Conditions: Clear Cell Renal Cell Carcinoma
Interventions: DRUG: ADI-270|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effects of 1592U89 Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Infants and Children
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Abacavir sulfate|DRUG: Lamivudine|DRUG: Stavudine|DRUG: Zidovudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Neuroimaging and Behavioral Assessments to Understand Late Talking
Status: RECRUITING
Conditions: Developmental Language Disorder|Language Delay|Language Development
Interventions: BEHAVIORAL: Intervention to address late talking
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 177Lutetium-octreotate Treatment Prediction Using Multimodality Imaging in Refractory NETs
Status: COMPLETED
Conditions: Gastroenteropancreatic Neuroendocrine Tumors
Interventions: DRUG: Intravenous injection of 177Lu-octreotate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Immediate Provisional Restorations on Bone Level Implants
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially
Interventions: DEVICE: Straumann® Bone Level SLActive Implant (4.1mm diameter)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pacifier Use During Phototherapy in Newborns With Hyperbilirubinemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Newborn Jaundice|Pacifier
Interventions: OTHER: Pacifier Use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness and Safety Study of the Iovera Device for the Temporary Reduction in the Appearance of Forehead Wrinkles
Status: COMPLETED
Conditions: Forehead Wrinkles
Interventions: DEVICE: iovera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Continuous Positive Airway Pressure (CPAP) on Cognitive and Functional Performance in Stroke Patients With Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Cerebrovascular Accident
Interventions: DEVICE: Nasal Continuous positive airway pressure - Tyco 420G
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SLS-002 (Intranasal Racemic Ketamine) in Adults With Major Depressive Disorder at Imminent Risk of Suicide
Status: COMPLETED
Conditions: Depressive Disorder, Major|Suicidal
Interventions: DRUG: SLS-002|DRUG: Placebo|OTHER: Standard of care|DEVICE: Intranasal device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Ruxolitinib and Erlotinib in Patients With EGFR-mutant Lung Adenocarcinoma With Acquired Resistance to Erlotinib
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Ruxolitinib|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Niraparib and Bevacizumab Maintenance Therapy in Platinum-sensitive Recurrent Ovarian Cancer Patients Previously Treated With a PARP Inhibitor
Status: UNKNOWN
Conditions: Platinum-sensitive Recurrent Ovarian Cancer Patients Previously Treated With a PARP Inhibitor
Interventions: DRUG: Niraparib-Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Homeopathic Remedy Kalium Bichromicum on Viscosity and Amount of Sputum Mechanically Ventilated ICU Patients.
Status: UNKNOWN
Conditions: Mechanically Ventilated ICU Patients
Interventions: DRUG: Kali bichromicum 10-60 (C30)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Trial of Multiple Dosing Regimens of ABT-719 for the Prevention of Acute Kidney Injury in Subjects Undergoing High Risk Cardiac Surgery
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: ABT-719|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Bifidobacterium Lactis and Inulin on Functional Constipation
Status: UNKNOWN
Conditions: Functional Constipation
Interventions: OTHER: B.lactis|OTHER: Inulin|OTHER: B.Lactis +Inulin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Chemotherapy Combination Cisplatin-Fluorouracil-Afatinib in Patients With Inoperable Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer|Gastroesophageal Junction Cancer
Interventions: DRUG: Cisplatin-5FU-Afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhanced Recovery After Laparoscopic Colorectal Surgery
Status: COMPLETED
Conditions: Rectal Cancer|Postoperative Pain
Interventions: DRUG: Bupivacaine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Shockwave Treatment for Greater Trochanteric Pain Syndrome
Status: COMPLETED
Conditions: Mobility Limitation|Trochanteric Syndrome|Gluteal Tendinitis|Bursitis Hip|Pain Syndrome
Interventions: DEVICE: Duolith SD1, STORZ Medical, Switzerland with F-SW applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pediatric Lupus Trial of Belimumab Plus Background Standard Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: belimumab 10mg/kg|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Axumin PET Scan in Germ Cell Tumor
Status: ACTIVE_NOT_RECRUITING
Conditions: Testis Cancer|Germ Cell Tumor|Testicular Cancer|Germ Cell Tumor of Testis|Germ Cell Tumor, Testicular, Childhood|Testicular Neoplasms|Testicular Germ Cell Tumor|Testicular Yolk Sac Tumor|Testicular Choriocarcinoma|Testicular Diseases|Germ Cell Cancer Metastatic|Germ Cell Neoplasm of Retroperitoneum|Germ Cell Cancer, Nos
Interventions: DRUG: Axumin PET scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Objective Structured Assessment of Technical Skills (OSATS) Evaluation of Shoulder Dystocia Management
Status: COMPLETED
Conditions: Shoulder Dystocia
Interventions: PROCEDURE: Hands-On Training|PROCEDURE: Demonstration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Pioglitazone on Stress Reactivity and Alcohol Craving
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: Pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics & Pharmacodynamics Study of Ropeginterferon Alfa-2b in Healthy Japanese and Caucasian Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ropeginterferon alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Tolvaptan to Reduce Urinary Supersaturation: a Pilot Proof of Principle Study
Status: COMPLETED
Conditions: Nephrolithiasis, Calcium Oxalate|Nephrolithiasis, Calcium Phosphate
Interventions: DRUG: Tolvaptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Belinostat and Yttrium Y 90 Ibritumomab Tiuxetan in Patients W/Relapsed Aggressive B-Cell NHL
Status: COMPLETED
Conditions: Anaplastic Large Cell Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Mantle Cell Lymphoma
Interventions: DRUG: belinostat|BIOLOGICAL: rituximab|RADIATION: yttrium Y 90 ibritumomab tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Trial of Ponatinib in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumor
Status: COMPLETED
Conditions: GIST
Interventions: DRUG: Ponatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of MAD as add-on Therapy in Comparison With Standard of Care in Children With ASD
Status: NOT_YET_RECRUITING
Conditions: Modified Atkins Diet|Autism Spectrum Disorder|Standard of Care
Interventions: DIETARY_SUPPLEMENT: Modified Atkin's Diet with standard of care|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Contact Monitoring of Subjects With an Optical Device: A Pilot Usability Study
Status: COMPLETED
Conditions: Usability
Interventions: DEVICE: Gili BioSensor System/ Gili Pro X BioSensor System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Oxaliplatin With FOLFOX4 in Patients With Normal and Abnormal Renal Function
Status: COMPLETED
Conditions: Gastrointestinal Cancer
Interventions: DRUG: Oxaliplatin (SR96669)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT