pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intermittent Checkpoint Inhibitor Therapy In Patients With Advanced Urothelial Carcinoma
Status: COMPLETED
Conditions: Urothelial Carcinoma
Interventions: DRUG: Pembrolizumab|DRUG: Atezolizumab|DRUG: Durvalumab|DRUG: Nivolumab|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Validation of a Postoperative Re-fracture Risk Model for Osteoporotic Spinal Fractures
Status: RECRUITING
Conditions: Osteoporosis Fracture|Osteoporosis Vertebral|Compression Fracture|Perform PVP / PKP Treatment
Interventions: PROCEDURE: PVP/PKP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Analgesic Effects of Expectation and Deep Brain Stimulation in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Pain
Interventions: BEHAVIORAL: Suggestions|DEVICE: Deep brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Safety and Efficacy Study of Obinutuzumab Alone or in Combination With Chemotherapy in Participants With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Bendamustine|DRUG: Chlorambucil|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Dose-dense Chemotherapy (ddEC-ddP) for Neoadjuvant Chemotherapy of HER2-negative Breast Cancer
Status: RECRUITING
Conditions: HER2-negative Breast Cancer|Neoadjuvant Chemotherapy
Interventions: DRUG: Epirubicin|DRUG: Cyclophosphamid|DRUG: Docetaxel|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The MULTINUTRIENT Maize Project: Results of Human Feeding Trial
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: β-carotene biofortified maize|OTHER: β-carotene supplemented maize|OTHER: Normal (non biofortified) maize without added β-carotene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of Composite Restorations Using Two-steps Universal Adhesive in Non-carious Cervical Lesion (NCCL)
Status: RECRUITING
Conditions: Non-carious Cervical Lesion
Interventions: OTHER: bonding strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Management for Degenerative Spinal Conditions
Status: COMPLETED
Conditions: Spinal Degenerative Disorder
Interventions: BEHAVIORAL: CBPT|OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Innovative Robotic Gait Trainer Use to Enable Walking in Children With Cerebral Palsy GMFCS III and IV
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: DEVICE: Robotic Gait Training|BEHAVIORAL: Functional Clinical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Prevention of Radial Artery Occlusion: Comparison of Three HEmostatiC Methods in Transradial Intervention
Status: UNKNOWN
Conditions: Occlusion of Artery|Radial Artery Injury|Complication
Interventions: PROCEDURE: Patent Hemostasis arm|PROCEDURE: ULTRA arm|DEVICE: Hemostatic disc arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Anrotinib in Combination With Capecitabine in Advanced Triple Negative Breast Cancer
Status: UNKNOWN
Conditions: Metastatic Triple-Negative Breast Cancer
Interventions: DRUG: Anlotinib|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ASTX727 in People With Malignant Peripheral Nerve Sheath Tumors (MPNST)
Status: RECRUITING
Conditions: Malignant Peripheral Nerve Sheath Tumors (MPNST)
Interventions: DRUG: ASTX727
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pembrolizumab With or Without Carboplatin and Paclitaxel on Immune Response in Patients With Recurrent or Stage IIIB-IV Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-Small Cell Lung Carcinoma|Stage IIIB Non-Small Cell Lung Cancer|Stage IV Non-Small Cell Lung Cancer
Interventions: DRUG: Carboplatin|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|BIOLOGICAL: Pembrolizumab|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osimertinib, Surgery, and Radiation Therapy in Treating Patients With Stage IIIB or IV Non-small Cell Lung Cancer With EGFR Mutations, NORTHSTAR Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Non-Small Cell Carcinoma|Recurrent Lung Non-Small Cell Carcinoma|Stage IIIB Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: DRUG: Osimertinib|RADIATION: Radiation Therapy|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CIK-Cells in Relapsing Patients With Acute Leukemia or Myelodysplastic Syndromes After SCT.
Status: UNKNOWN
Conditions: Myelodysplastic Syndromes|Acute Leukemia
Interventions: DRUG: CIK-Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Respiratory Physiotherapy Treatments in Postcovid-19 Patients.
Status: COMPLETED
Conditions: COVID-19|Respiratory Distress Syndrome
Interventions: DEVICE: PowerBreathe and PEP Therosold tools
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation
Status: TERMINATED
Conditions: Opioid-Induced Constipation
Interventions: DRUG: CB-5945|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Nerve Stimulation for Back Pain in the Emergency Department (TENS-ED)
Status: COMPLETED
Conditions: Back Pain|Muscle Pain|Acute Pain|Lower Back Pain|Lower Back Pain Mechanical
Interventions: DEVICE: Transcutaneous Electrical Nerve Stimulation (TENS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Computer Guided Surgery (vs) Conventional Model Surgery in Treatment of Skeletal Open Bite
Status: UNKNOWN
Conditions: Apertognathia
Interventions: PROCEDURE: Computer guided surgery|PROCEDURE: Conventional model surgery|DEVICE: 2D cephalometric radiograph|DEVICE: 3D computerized tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trametinib or Combination Chemotherapy in Treating Patients With Refractory or Advanced Biliary or Gallbladder Cancer or That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Adult Cholangiocarcinoma|Advanced Adult Hepatocellular Carcinoma|BCLC Stage C Adult Hepatocellular Carcinoma|BCLC Stage D Adult Hepatocellular Carcinoma|Hilar Cholangiocarcinoma|Localized Non-Resectable Adult Liver Carcinoma|Recurrent Adult Liver Carcinoma|Recurrent Childhood Liver Cancer|Recurrent Extrahepatic Bile Duct Carcinoma|Recurrent Gallbladder Carcinoma|Stage II Gallbladder Cancer|Stage III Childhood Hepatocellular Carcinoma|Stage IIIA Gallbladder Cancer|Stage IIIB Gallbladder Cancer|Stage IV Childhood Hepatocellular Carcinoma|Stage IV Distal Bile Duct Cancer|Stage IVA Gallbladder Cancer|Stage IVB Gallbladder Cancer|Unresectable Extrahepatic Bile Duct Carcinoma
Interventions: DRUG: Capecitabine|DRUG: Fluorouracil|OTHER: Laboratory Biomarker Analysis|DRUG: Leucovorin Calcium|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-in-human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HM12470
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: BIOLOGICAL: HM12470|BIOLOGICAL: Active comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DEFENDOR: A Multicenter Prospective Observational Post-registration stuDy of Extimia® (INN: empEgfilrastim) to Evaluate Efficacy and saFEty in patieNts With soliD tumORs
Status: UNKNOWN
Conditions: Patients With Solid Tumours Who Receive Myelosupressive Therapy
Interventions: DRUG: Empegfilgrastim
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Safety, Tolerability and Pharmacokinetic Study of ZSP1273 in Healthy Volunteers.
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: ZSP1273 100 mg|DRUG: Placebo 100 mg|DRUG: ZSP1273 200 mg|DRUG: Placebo 200 mg|DRUG: ZSP1273 400 mg|DRUG: Placebo 400 mg|DRUG: ZSP1273 600 mg|DRUG: Placebo 600 mg|DRUG: ZSP1273 900 mg|DRUG: Placebo 900 mg|DRUG: ZSP1273 1200 mg|DRUG: Placebo 1200 mg|DRUG: ZSP1273|DRUG: Placebo|DRUG: ZSP1273 Low Dose|DRUG: Placebo|DRUG: ZSP1273 Median Dose|DRUG: Placebo|DRUG: ZSP1273 High Dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Botulinum Toxin Injection on Sensation and Postural Control in Children With Hemiplegic Cerebral Palsy
Status: UNKNOWN
Conditions: Cerebral Palsy|Hemiplegic Cerebral Palsy
Interventions: DRUG: Botulinum toxin type-A (Onabotulinum toxin type-A)|OTHER: Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin ER 750 mg Tablets, Fasting
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Glucophage® XR 750 mg Tablets|DRUG: Metformin ER 750 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MMEPT for Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: RRTBIMS|BEHAVIORAL: Multimedia Multicultural Educational Program for TBI (MMEPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of IFNa Kinoid in Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: IFN-K
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Normal Saline Versus Lactated Ringer's Solution for Acute Pancreatitis Resuscitation
Status: RECRUITING
Conditions: Acute Pancreatitis
Interventions: DRUG: Lactated Ringer Solution|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neo-TACE-HAIC for BCLC B Stage HCC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: neo-TACE-HAIC+Surgery|PROCEDURE: Surgery alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Anti-CD20/CD30 CAR-T Cells in Subjects With Relapsed/Refractory Lymphoma
Status: RECRUITING
Conditions: Relapsed/Refractory Lymphoma
Interventions: GENETIC: anti-CD20/CD30-CAR-T cells|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension to Study of Effects of Pomegranate Extract on Rising PSA Levels After Primary Therapy for Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: pomegranate extract|DIETARY_SUPPLEMENT: pomegranate juice|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Application of Large Volume Acute Normovolemic Hemodilution in Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Surgery|Acute Normovolemic Hemodilution
Interventions: PROCEDURE: Large volume Acute Normovolemic Hemodilution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Docetaxel + Oxaliplatin + S-1 in Potentially Operable Gastric or Gastroesophageal Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: DOCETAXEL|DRUG: S-1|DRUG: OXALIPLATIN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MIND-Matosinhos: Multiple Interventions to Prevent Cognitive Decline
Status: UNKNOWN
Conditions: Cognitive Dysfunction|Cognition Disorder|Memory Disorders|Cognitive Impairment|Neurocognitive Disorders
Interventions: BEHAVIORAL: Cognitive training|BEHAVIORAL: Physical exercise|BEHAVIORAL: Nutrition education|BEHAVIORAL: Capacitation to deal with cognitive decline|OTHER: Diagnosis and correction of hearing impairment|BEHAVIORAL: Cognitive training|BEHAVIORAL: Physical exercise|BEHAVIORAL: Nutrition education|BEHAVIORAL: Capacitation to deal with cognitive decline|BEHAVIORAL: Diagnosis and correction of hearing impairment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ribociclib-endocrine Combination Therapy Versus Chemotherapy as 1st Line in Visceral mBC
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Ribociclib|OTHER: Mono-chemotherapy|OTHER: Endocrine-Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exemestane As Treatment In Neoadjuvant Setting For Operable Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: exemestane (Aromasin®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parents Matter!: Interventions to Promote Effective Parent-Child Communication
Status: COMPLETED
Conditions: HIV Infections|Sexually Transmitted Diseases|Pregnancy
Interventions: BEHAVIORAL: Full Parent communication intervention|BEHAVIORAL: Brief Parent Communication Intervention|BEHAVIORAL: Control Parent Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Milnacipran and Neurocognition, Pain and Fatigue in Fibromyalgia : A 13-week Randomized, Placebo Controlled Cross Over Trial
Status: COMPLETED
Conditions: Fibromyalgia|Neurocognition
Interventions: DRUG: Milnacipran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Plasma Exchange to Alleviate Hyperinflammatory Condition During Severe Covid-19 Infections
Status: UNKNOWN
Conditions: Intensive Care Units|ARDS, Human|Covid19
Interventions: OTHER: Therapeutic plasma exchange : 3 sessions in 3 consecutive days (day 1 to day 3)|OTHER: Usual treatments in intensive care unit according to the current state of knowledge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-GD2 4th Generation CART Cells Targeting Refractory and/or Recurrent Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma|Effects of Immunotherapy
Interventions: BIOLOGICAL: Anti-GD2 CART
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ethyl Chloride Vapocoolant as Anesthesia for Arterial Punctures
Status: COMPLETED
Conditions: Anesthesia|Pain
Interventions: DRUG: Ethyl chloride|DRUG: Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SIL-TEP vs TEP for Inguinal Hernia Repair in Day Surgery
Status: UNKNOWN
Conditions: Hernia, Inguinal
Interventions: PROCEDURE: SIL-TEP Inguinal Hernia Repair|PROCEDURE: TEP Inguinal Hernia Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Order of Treatment in Lumbar Spinal Stenosis
Status: WITHDRAWN
Conditions: Lumbar Spinal Stenosis
Interventions: OTHER: physical therapy|PROCEDURE: lumbar interlaminar epidural steroid injection|DRUG: epidural steroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eryaspase With Modified FOLFIRINOX in Advanced Pancreatic Ductal Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Pancreatic Ductal Adenocarcinoma|Metastatic Pancreatic Ductal Adenocarcinoma
Interventions: BIOLOGICAL: Eryaspase|DRUG: FOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRE- MISTIC: MRI and Cine Imaging to Improve Staging of Tumors In the Colon
Status: NOT_YET_RECRUITING
Conditions: Colon Cancer
Interventions: DIAGNOSTIC_TEST: MRI and CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lumbar Stenosis Outcomes Research (LUSTOR)
Status: COMPLETED
Conditions: Lumbar Spinal Stenosis
Interventions: DRUG: Pregabalin|DRUG: Diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Regular, Musical and Electric Toothbrushes in Plaque Removal in Children
Status: COMPLETED
Conditions: Children, Adult|Plaque
Interventions: DEVICE: Regular Toothbrush|DEVICE: Musical toothbrush|DEVICE: Electric toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Study of Depigoid Vaccine Dermatophagoides Pteronyssinus or 50% Dermatophagoides Pteronyssinus / 50% Dermatophagoides Farinae (500 DPP/ml), to Treat Allergic Rhinitis or Rhinoconjunctivitis With or Without Asthma
Status: TERMINATED
Conditions: Allergic Rhinitis|Rhinoconjunctivitis|Mild Persistent Asthma|Mild Intermittent Asthma
Interventions: BIOLOGICAL: Depigoid® (500 DPP/ml)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate Taste and Relative Bioavailability of Two Microsphere Formulations of Crizotinib in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Treatment A|DRUG: Treatment B|DRUG: Treatment C|DRUG: Treatment D|DRUG: Treatment E|DRUG: Treatment F|DRUG: Treatment G|DRUG: Treatment H
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Naloxone and Methylnaltrexone on Esophageal Sensitivity in Health
Status: COMPLETED
Conditions: Endogenous and Esophageal Sensitivity
Interventions: DRUG: Naloxone|DRUG: Methylnaltrexone Bromide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mechanism of Action of Galiximab in Subjects With Previously Untreated Follicular Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Lymphoma, Non-Hodgkin's
Interventions: DRUG: Galiximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebral and Peripheral Near Infrared Spectroscopy Monitoring in Low and High Flow Anaesthesia in Pediatric
Status: RECRUITING
Conditions: Child, Only|Inhalation; Vapor|Anesthesia|Cerebral Oxygenation|Cerebral Hypoxia|Peripheral Oxygenation
Interventions: DEVICE: NIRS ,Ventilation parameters|DEVICE: Oxygen concentration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: WJMSCs Anti-inflammatory Therapy in Acute Myocardial Infarction
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: BIOLOGICAL: Intravenous infusion placebo|BIOLOGICAL: Intravenous infusion WJMSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide Plus ICE in the Treatment of Refractory and Relapsed DLBCL
Status: UNKNOWN
Conditions: Diffuse Large B-Cell Lymphoma Refractory
Interventions: DRUG: Lenalidomide|DRUG: Ifosfamide|DRUG: Carboplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Insulin Glargine Versus Regular Insulin Based Regimens in Glycemic Control After Acute Stroke
Status: UNKNOWN
Conditions: Acute Stroke|Hyperglycemia
Interventions: DRUG: Insulin Glargine|DRUG: Regular Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Limits of the Social Benefit Motive Among High-risk Patients: a Field Experiment on Influenza Vaccination Behaviour
Status: COMPLETED
Conditions: Influenza Vaccine|Behavioral Intervention|Self-benefit|Social-benefit
Interventions: BEHAVIORAL: Self-benefit message|BEHAVIORAL: Other-benefit message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Total Marrow and Lymphoid Irradiation as Conditioning Regimen Before Hematopoietic Cell Transplantation in Patients With Myelodysplastic Syndrome or Acute Leukemia
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|High Risk Myelodysplastic Syndrome|Myelodysplastic Syndrome
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Fludarabine Phosphate|BIOLOGICAL: Granulocyte Colony-Stimulating Factor|PROCEDURE: Hematopoietic Cell Transplantation|PROCEDURE: Intensity-Modulated Radiation Therapy|DRUG: Mycophenolate Mofetil|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter, Randomized, Controlled Study of the Effect of Lotemax on Initiation of Dry Eye Treatment With Restasis
Status: COMPLETED
Conditions: Dry Eye Disease|Keratoconjunctivitis Sicca
Interventions: DRUG: Lotemax|DRUG: Restasis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Ex-vivo Examination of Excisions of Skin Tumors by Confocal Optical Coherence Tomography (LC-OCT) With Integrated Dermoscopy and Comparison With Histology (DERMOCTAV)
Status: UNKNOWN
Conditions: Cutaneous Tumor|Optical Coherence Tomography|Basal Cell Carcinoma|Squamous Cell Carcinoma|Melanoma
Interventions: PROCEDURE: Confocal optical coherence tomography - OCTAVE
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hyaluronic Acid Gels for Upper Lid Retraction in Active Stage Thyroid Eye Disease
Status: TERMINATED
Conditions: Thyroid Eye Disease
Interventions: DRUG: Hyaluronic Acid Gel injection|DRUG: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Surgical Pain Outcomes
Status: ACTIVE_NOT_RECRUITING
Conditions: Post Surgical Pain|Surgery
Interventions: OTHER: Self-directed mindfulness utilizing a multi-sensor EEG-supported device with neurofeedback-assisted and technology-supported meditation|OTHER: Provider-directed mindfulness|OTHER: Conventional Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Montmorency Cherry Supplementation, Sleep, and Inflammation
Status: ACTIVE_NOT_RECRUITING
Conditions: Insomnia Chronic|Inflammation
Interventions: DIETARY_SUPPLEMENT: Montmorency cherry supplement|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab + Guadecitabine in Patients With Checkpoint Inhibitor Refractory or Resistant Urothelial Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Urothelial Carcinoma
Interventions: DRUG: Atezolizumab|DRUG: Guadecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluating PRO-240 Ophthalmic Solution Compared to Optive®
Status: NOT_YET_RECRUITING
Conditions: Dry Eye Disease|Dry Eye Sensation|Ocular Surface Disease
Interventions: DRUG: PRO-240|DRUG: Optive®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: mHealth Smartphone App and Postpartum Glucose Intolerance for Patients With GDM
Status: RECRUITING
Conditions: Gestational Diabetes|PreDiabetes|Pregnancy Related|Pregnancy, High Risk
Interventions: BEHAVIORAL: Malama App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of Surrounding Electroacupuncture in the Treatment of Acute Lateral Ankle Sprain
Status: RECRUITING
Conditions: Electroacupuncture
Interventions: OTHER: electroacupuncture combined with surrounding acupuncture|OTHER: sham electroacupuncture|OTHER: ice compress combined with brake rest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Galunisertib (LY2157299) in Combination With Nivolumab in Advanced Refractory Solid Tumors and in Recurrent or Refractory NSCLC, or Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Solid Tumor|Non-Small Cell Lung Cancer Recurrent|Hepatocellular Carcinoma Recurrent
Interventions: DRUG: Galunisertib|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avatrombopag for the Treatment of Thrombocytopenia in Adults Scheduled for a Surgical Procedure
Status: TERMINATED
Conditions: Thrombocytopenia
Interventions: DRUG: Avatrombopag 60 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Early Multimodal Physiotherapy in Patients With Reverse Shoulder Prosthesis
Status: NOT_YET_RECRUITING
Conditions: Shoulder Fractures|Prosthesis User
Interventions: OTHER: REMOVE|OTHER: CONTROL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity & Safety of GSK's Avian Flu Vaccine 1557484A Given to Adults Aged ≥18 Years
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: A/turkey H5N1 vaccine|BIOLOGICAL: Influenza A (H5N1) Virus Monovalent Vaccine, Adjuvanted (A/Indonesia)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Effects of a Computerized Training Program Coupled With Cognitive Behavioral Therapy (CBT) for OCD.
Status: UNKNOWN
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Personalized Computer Program|BEHAVIORAL: CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Clinical Trial to Evaluate the Safety and Efficacy of Plasmid DNA Therapeutic Vaccine(GX-188E)
Status: UNKNOWN
Conditions: Cervical Intraepithelial Neoplasia
Interventions: BIOLOGICAL: GX-188E|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protective Analgesia for Postoperative Pain Relief Following Day Case Oral Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Wisdom Tooth
Interventions: DRUG: Brufen retard|DRUG: ibuprofen|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improving Adherence Healthy Lifestyle With a Smartphone Application Based After Surgery in Cancer Patients
Status: COMPLETED
Conditions: Secondary Prevention
Interventions: OTHER: health education for lymphedema prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Therapeutic Efficacy of APD-209 Eye Drops in Treatment of Epidemic Keratoconjunctivitis (EKC)
Status: COMPLETED
Conditions: Viral Conjunctivitis
Interventions: DRUG: APD-209 Eye drops|DRUG: APD-209 Placebo Eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pazopanib, Irinotecan and Cetuximab in Combination to Treat 2nd Line Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Neoplasms, Colorectal
Interventions: DRUG: Pazopanib|DRUG: Cetuximab|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the Anti-COVID-19 Antibody SA55 for Injection in Patients With Hematological Disorders Who Are Persistently Positive for COVID-19
Status: RECRUITING
Conditions: Hematological Disorders|COVID-19
Interventions: BIOLOGICAL: Anti-COVID-19 Antibody SA55 for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intradermal Ipilimumab and Nivolumab in High Risk Stage II Melanoma
Status: NOT_YET_RECRUITING
Conditions: Melanoma
Interventions: DRUG: Ipilimumab|DRUG: Nivolumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dabigatran in Patients With Atrial Fibrillation and Mitral Biological Prostheses
Status: UNKNOWN
Conditions: Mitral Valve Stenosis and Insufficiency|Atrial Fibrillation
Interventions: DRUG: Dabigatran Etexilate|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Leukemia, Lymphocytic|Leukemia, B-cell|Small Lymphocytic Lymphoma
Interventions: DRUG: Pirtobrutinib|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Crizotinib in Lobular Breast, Diffuse Gastric and Triple Negative Lobular Breast Cancer or CDH1-mutated Solid Tumours
Status: ACTIVE_NOT_RECRUITING
Conditions: Lobular Breast Carcinoma|Gastric Cancer|Triple Negative Breast Cancer|CDH1 Gene Mutation
Interventions: DRUG: Crizotinib Oral Capsule [Xalkori]|DRUG: Fulvestrant 50 MG/ML Prefilled Syringe [Faslodex or generic]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effects of Different Exercise Programs on Injury Risk and Sports Performance in Adolescent Basketball Players
Status: COMPLETED
Conditions: Sport Injury
Interventions: OTHER: Routine Exercise Program|OTHER: Core Stability Exercise Program|OTHER: Body Weight Neuromuscular Warm-Up Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Test-Retest Reproducibility of 18F-DCFPyL PET/CT in the Evaluation of Patients With Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: 18F-DCFPyL Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Romosozumab Versus Denosumab for Osteoporosis in Long-term Glucocorticoid Users
Status: COMPLETED
Conditions: Glucocorticoid-induced Osteoporosis
Interventions: DRUG: Romosozumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Cost Savings for Transtibial Amputees Wearing the Controlled Energy Storage and Return (CESR) Foot
Status: COMPLETED
Conditions: Transtibial Amputation
Interventions: DEVICE: CESR Prosthetic Foot|DEVICE: typical prosthetic foot|DEVICE: standardized prosthetic foot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab Combined With Pemetrexed and Carboplatin for the Study of EGFR-mutated Lung Squamous NSCLC Treatment
Status: UNKNOWN
Conditions: Lung Cancer Stage II
Interventions: DRUG: Camrelizumab+ pemetrexed + platinum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Voluven® for the Prevention of Hypotension During Spinal Anesthesia for Cesarean Section
Status: COMPLETED
Conditions: Hypotension
Interventions: DRUG: HES 130/0.4 (6%) in sodium chloride (solution for infusion)|DRUG: Ringer's Lactate solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Trial of Docosahexaenoic Acid Supplementation During Pregnancy to Prevent Deep Placentation Disorders
Status: UNKNOWN
Conditions: Premature Birth|Preeclampsia|Fetal Growth Retardation|Stillbirth
Interventions: DIETARY_SUPPLEMENT: Docosahexaenoic acid (DHA)|DIETARY_SUPPLEMENT: Placebo (for Docosahexaenoic acid (DHA))
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Posterior Capsule Opacification Development With Two Different Intraocular Lenses
Status: COMPLETED
Conditions: Posterior Capsule Opacification|Cataract
Interventions: DEVICE: HOYA iMics Y-60H|DEVICE: PhysIOL microAY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Seprafilm® Adhesion Barrier and Cesarean Delivery
Status: COMPLETED
Conditions: Adhesions|Cesarean Section|Delivery, Obstetric
Interventions: DEVICE: modified sodium hyaluronic acid and carboxymethylcellulose|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study to Evaluate the Combination of Rituximab and DepoCyte® in the C5R Chemotherapy Protocol in Patients Between the Ages of 18 and 60 Years With Primary Cerebral Non-Hodgkin Lymphoma and Systemic Diffuse Large B-cell Lymphoma With Neuromeningeal Invasion at Diagnosis
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|Diffuse Large B-cell Lymphoma
Interventions: DRUG: Rituximab|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Imovax Polio in Chinese Infants and Children
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: Inactivated Poliomyelitis vaccine|BIOLOGICAL: Inactivated Poliomyelitis vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Long-term Effect of Daily Jarlsberg Cheese Intake in Patient With Osteopenia
Status: NOT_YET_RECRUITING
Conditions: Osteopenia|Osteoporosis
Interventions: DIETARY_SUPPLEMENT: Jarlsberg cheese
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Individualized Therapy on Hyperphosphatemia in Maintenance Hemodialysis Patients
Status: COMPLETED
Conditions: Hyperphosphatemia|End-stage Renal Disease
Interventions: OTHER: enhanced individualised therapy|OTHER: non-enhanced individualised therapy|OTHER: regular intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK Study to Evaluate the Effect of PLC on Healthy Chinese Subjects by Multiple-doses
Status: COMPLETED
Conditions: Peripheral Arterial Diseases
Interventions: DRUG: Propionyl-L-Carnitine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging Study of 18F-FAC PET Scans to Assess Standard Treatment in People With Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer|Pancreatic Ductal Adenocarcinoma
Interventions: DIAGNOSTIC_TEST: PET Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study of Anetumab Ravtansine in Adults With Solid Tumors Who Have Been Treated in Previous Bayer-sponsored Anetumab Ravtansine Studies
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: BAY94-9343 (Anetumab ravtansine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Pharmacokinetic and Bioavailability of Envarsus® vs. Advagraf® in Liver Transplant Recipients
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DRUG: Treatment 2 weeks Envarsus followed by 2 weeks Advagraf|DRUG: Treatment 2 weeks Advagraf followed by 2 weeks Envarsus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Prospective Personalized Immune and Target Identification Trial
Status: RECRUITING
Conditions: Central Nervous System Neoplasms|Pediatric Cancer|GEN1 Gene Mutation|Tumor, Brain
Interventions: DEVICE: FoundationOneHeme
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 6-Month Extension Trial of Asenapine With Olanzapine in Negative Symptom Patients Who Completed the Protocol 25543 (25544)(P05777)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: asenapine|DRUG: olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Korean Red Ginseng Extract on Blood Flow in Healthy Adults
Status: RECRUITING
Conditions: Cardiovascular Diseases|Blood Pressure Disorders|Vasodilation|Platelet Aggregation
Interventions: DIETARY_SUPPLEMENT: Korean Red Ginseng Extract Powder 120 mg/tablet|DIETARY_SUPPLEMENT: Korean Red Ginseng Extract Powder 500 mg/tablet|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pre-Emptive Analgesia in Ano-Rectal Surgery
Status: COMPLETED
Conditions: Hemorrhoids|Fissure in Ano|Rectal Fistula|Anal Condyloma
Interventions: DRUG: Gabapentin|DRUG: Ketamine|DRUG: Acetaminophen|DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Risk Factors of Chinese Kidney Transplant Recipients DSA Based on MPA Immunosuppressive Regimen
Status: UNKNOWN
Conditions: Kidney Transplant Recipients
Interventions: DRUG: Mycophenolate Mofetil Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Innovating CBT-I for Cancer Survivors: An Optimization Trial
Status: NOT_YET_RECRUITING
Conditions: Cancer Survivorship|Insomnia
Interventions: BEHAVIORAL: Survivorship Sleep Program with Individual Delivery + No Booster Sessions|BEHAVIORAL: Survivorship Sleep Program with Group Delivery + No Booster Sessions|BEHAVIORAL: Survivorship Sleep Program with Individual Delivery + 3 Booster Sessions|BEHAVIORAL: Survivorship Sleep Program with Group Delivery + 3 Booster Sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: GMVs in Primary Care: An RCT of Group-Based Versus Individual Appointments to Reduce HbA1c in Older People
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus (T2DM)
Interventions: BEHAVIORAL: Group Appointments|BEHAVIORAL: Individual Appointments (IAs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare COREG CR to COREG CR Fixed-dose Combination in Patients With High Blood Pressure
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: SK&F-105517 (COREG CR FDC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1 Knockout EBV-CTLs for Advanced Stage Epstein-Barr Virus (EBV) Associated Malignancies
Status: UNKNOWN
Conditions: Stage IV Gastric Carcinoma|Stage IV Nasopharyngeal Carcinoma|T-Cell Lymphoma Stage IV|Stage IV Adult Hodgkin Lymphoma|Stage IV Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beta-Blocker in Chronic Obstructive Pulmonary Disease (COPD) Study
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: bronchodilator response
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multiphase Optimization Trial of Incentives for Veterans to Encourage Walking
Status: COMPLETED
Conditions: Sedentary Behavior|Exercise|Walking|Motivation|Hypertension|Depression|Body Mass Index
Interventions: BEHAVIORAL: Walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bioequivalence Study for Benzyl Alcohol Lotion 5%.
Status: COMPLETED
Conditions: Head Lice
Interventions: DRUG: Benzyl Alcohol Lotion 5%|DRUG: Ulesfia (benzyl alcohol lotion) 5%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reolysin in Combination With FOLFOX6 and Bevacizumab or FOLFOX6 and Bevacizumab Alone in Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Folfox plus Bevacizumab and reolysin|DRUG: Folfox plus Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decreasing REcurrent Pain and Anxiety in Medical Procedures With a Pediatric Population: Trial
Status: WITHDRAWN
Conditions: Pain|Burns|Child|Anxiety
Interventions: DEVICE: VR distraction via Oculus Rift|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psilocybin-assisted Therapy for Alcohol Use Disorder
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder|Alcohol Dependence|Depression|Anxiety
Interventions: DRUG: Psilocybin|DRUG: Niacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Neoadjuvant Combination Immunotherapy for Stage III Melanoma
Status: RECRUITING
Conditions: Cutaneous Melanoma
Interventions: DRUG: Pembrolizumab|DRUG: Talimogene Laherparepvec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER