pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Evaluate Safety, Pharmacokinetics, and Pharmacodynamics of Escalating Doses of SAR438544 in Comparison to Placebo and Glucagon in Healthy Subjects and Type 1 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: SAR438544|DRUG: placebo|DRUG: r-glucagon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Comparing the Effect of Ligamentum Teres Cardiopexy on de Novo GERD Post LSG
Status: UNKNOWN
Conditions: GERD
Interventions: PROCEDURE: laparoscopic sleeve gastrectomy|PROCEDURE: ligamentum teres cardiopexy with sleeve gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Fibroblast Growth Factor-1 (FGF-1) for the Treatment of Coronary Heart Disease
Status: UNKNOWN
Conditions: Coronary Disease|Coronary Heart Disease|Myocardial Ischemia|Coronary Arteriosclerosis
Interventions: COMBINATION_PRODUCT: Human Recombinant Fibroblast Growth Factor-1 (FGF 1-141) - low dose|COMBINATION_PRODUCT: Human Recombinant Fibroblast Growth Factor-1 (FGF1-141) - high dose|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Examining Early Palliative Care in Newly Diagnosed Cancer Patients
Status: COMPLETED
Conditions: Cancer
Interventions: COMBINATION_PRODUCT: Palliative care|COMBINATION_PRODUCT: Standard oncological care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment for Acute Postoperative Voiding Dysfunction
Status: COMPLETED
Conditions: Urinary Retention
Interventions: DEVICE: PTNS Active Treatment|OTHER: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety and Quality of Life of Patients Using Biojector Versus Needles for Fuzeon Administration
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: DEVICE: Biojector
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sedation and Ease of Weaning From Mechanical Ventilation
Status: COMPLETED
Conditions: Respiratory Failure|Midazolam Overdose|Chronic Obstructive Pulmonary Disease|Weaning Failure
Interventions: DRUG: Daily interruption of midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib and Temsirolimus in Treating Patients With Recurrent Malignant Glioma
Status: COMPLETED
Conditions: Adult Anaplastic Astrocytoma|Adult Anaplastic Oligodendroglioma|Adult Diffuse Astrocytoma|Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Adult Mixed Glioma|Adult Pilocytic Astrocytoma|Adult Pineal Gland Astrocytoma|Adult Subependymal Giant Cell Astrocytoma|Recurrent Adult Brain Tumor
Interventions: DRUG: erlotinib|DRUG: temsirolimus|PROCEDURE: therapeutic conventional surgery|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Target Engagement for Oxytocin: Dose Ranging Study
Status: COMPLETED
Conditions: Schizophrenia Spectrum
Interventions: DRUG: Intranasal Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: CRLX101 Plus Bevacizumab in Advanced RCC
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: CRLX101 (Cerulean)|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: LASER Pilot Project
Status: RECRUITING
Conditions: Acquired Absence of Lower Limb|Scar Condition and Fibrosis of the Skin
Interventions: PROCEDURE: Fractional CO2 Laser Ablative Resurfacing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Guiding Sedation Level by Respiratory Effort Versus Usual Care in Mechanically Ventilated Patients: A Randomized Controlled Trial (EFFORT-GUIDE Trial 2)
Status: RECRUITING
Conditions: ARDS|Respiratory Effort|Mechanical Ventilation Complication|Sedation
Interventions: OTHER: The respiratory effort parameters guide sedative dosage.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of the Trifunctional Antibody Catumaxomab Administered Intra- and Postoperatively in Patients With Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Epithelial Ovarian Cancer
Interventions: DRUG: Catumaxomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pharmacokinetics and Safety Tolerability of Higher Doses of Rifampic
Status: COMPLETED
Conditions: Clinical Trial
Interventions: DRUG: Evaluation of high dose rifampicin in children
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Assessing the Value of an Antibiotic Protocol Guided by Serum Procalcitonin in Acute Exacerbations of Chronic Obstructive Pulmonary Disease in Intensive Care
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Antibiotic therapy randomization|OTHER: Serum PCT dosage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Application of Amiloride in the Treatment of Patient With Chronic Kidney Disease In Reducing Urinary PROtein
Status: COMPLETED
Conditions: Chronic Kidney Diseases
Interventions: DRUG: Amiloride|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development of a Novel Transdiagnostic Intervention for Anhedonia - R33 Phase
Status: COMPLETED
Conditions: Anhedonia
Interventions: BEHAVIORAL: Behavioral Activation|BEHAVIORAL: Mindfulness Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Mitoxantrone, Etoposide and Gemtuzumab Ozogamicin for Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Gemtuzumab ozogamicin|DRUG: Mitoxantrone|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MNK Inhibitor AUM001 in Combination With Either Pembrolizumab or Irinotecan to Treat Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Tinodasertib|DRUG: Pembrolizumab|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Sevoflurane With Propofol Sedation in ESRF Patients
Status: UNKNOWN
Conditions: Sevoflurane|Kidney Diseases|Procedural Hypotension
Interventions: DRUG: Sevoflurane inhalant product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects on Mortality and Clinical Course of a Patient's Choice Model for Opioid Maintenance Treatment for Opioid Dependence - Evaluation of a System Enabling a Large Expansion of Treatment Providers and Treatment Access
Status: NOT_YET_RECRUITING
Conditions: Opioid Dependence|Overdose
Interventions: DRUG: Opioid maintenance treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Diagnosis and Early Treatment of Alzheimer's Disease Based on Senile Plaque Imaging
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment|Biomarker|Diagnosis|Treatment
Interventions: DRUG: Huperzine A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Caudal Block Versus Ultrasound Guided Ilioinguinal/Iliohypogastric Block in Pediatric Patient
Status: COMPLETED
Conditions: Surgery
Interventions: PROCEDURE: inguinal hernia surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Experimental AD4-H5-VTN Vaccine in Healthy Volunteers
Status: COMPLETED
Conditions: H5N1 Influenza
Interventions: BIOLOGICAL: Ad4-H5-VTN vaccination-tonsillar route|BIOLOGICAL: Ad4-H5-vaccination-oral route
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect Of E-Mobıle Traınıng Gıven Postnatal Perıod On Postnatal Comfort And Breastfeedıng Self-Effıcıency
Status: NOT_YET_RECRUITING
Conditions: Breastfeeding
Interventions: DEVICE: mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Quality of Life Study With Adalimumab in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Adalimumab|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot: Insulin Sensitivity/Management in Hyperglycemic Patients in Perioperative Period ESRD/Non-ESRD
Status: TERMINATED
Conditions: End-Stage Renal Disease|Diabetes Mellitus
Interventions: DRUG: IV Novolin R human insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ALK21-018: Effects of Medisorb® Naltrexone (VIVITROL®) on Alcohol Craving in Treatment-seeking, Alcohol-dependent Adults
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: VIVITROL 380 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Methylprednisolone or Methotrexate in the Maintenance Treatment of Nasal Polyposis
Status: COMPLETED
Conditions: Nasal Polyposis
Interventions: DRUG: Emthexate|DRUG: Prednol|DRUG: Mometasone Furoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Adipiplon, Placebo and an Active Control in Primary Insomniacs
Status: TERMINATED
Conditions: Primary Insomnia
Interventions: DRUG: Adipiplon|DRUG: Placebo|DRUG: Ambien CR|DRUG: Adipiplon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Scapular Stabilization Exercises on the Upper Extremity in Patients With Chronic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Bobath+Scapular Stabilization Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Observational Trial to Evaluate Quality of Life After Stereotactic Ablative Radiation Therapy in Patients With Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Cancer|Quality of Life|Stereotactic Body Radiation Therapy|Observational
Interventions: OTHER: observational
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Phase III Clinical Study of Herombopag for the Treatment of Thrombocytopenia in Chronic Liver Disease Patients Undergoing Elective Invasive Surgery
Status: RECRUITING
Conditions: Thrombocytopenia in Chronic Liver Disease Patients Undergoing Elective Invasive Surgery
Interventions: DRUG: Herombopag tablets|DRUG: Herombopag placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alkaline Water and Salivary Bacterial Count
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Caries
Interventions: DRUG: Alkaline water (FLO water- Bottled drinking water- the Egyption Saudi Company for natural water- made in Egypt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Rituximab and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Recurrent Primary CNS Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|RADIATION: yttrium Y 90 ibritumomab tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Yttrium-90 (Y90) Radioembolization for the Treatment of Early Stage Renal Cell Carcinoma, The RENEGADE Trial
Status: NOT_YET_RECRUITING
Conditions: Stage I Renal Cell Cancer|Stage II Renal Cell Cancer
Interventions: PROCEDURE: Angiogram|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|RADIATION: Radioembolization|PROCEDURE: Single Photon Emission Computed Tomography|OTHER: Survey Administration|RADIATION: Yttrium Y 90 Glass Microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Daptomycin During Cardiopulmonary Bypass Surgery
Status: COMPLETED
Conditions: Late Effects of Surgery|Staphylococcus Aureus|Surgical Site Infection
Interventions: DRUG: daptomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Therapeutic Drug Monitoring-baSed adalimuMab De-escalatiOn in nOn-infecTious cHronic Uveitis
Status: NOT_YET_RECRUITING
Conditions: Uveitis|Chronic Disease
Interventions: DIAGNOSTIC_TEST: Blood sample|DRUG: Adalimumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Olfactory Disfunction and Co-ultraPEALut
Status: COMPLETED
Conditions: Anosmia|Covid19|Hyposmia|Parosmia|Treatment Compliance
Interventions: COMBINATION_PRODUCT: co-ultraPEALut|PROCEDURE: Olfactory Rehab|DRUG: PEA-LUT 1 sachet|DRUG: PEA-LUT 2 sachet day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of a Caspase Inhibitor in Patients Undergoing Liver Transplantation
Status: COMPLETED
Conditions: Liver Transplantation|Hepatitis|Cholestasis|Carcinoma, Hepatocellular
Interventions: DRUG: IDN-6556|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Chronic Pain and Social Vulnerability: Prevalence and Predictive Factors of the Social Vulnerability in Evaluation and Treatment of the Pain Center (CETD)
Status: UNKNOWN
Conditions: Chronic Pain
Interventions: OTHER: Questionnaire EPICES (Evaluation of the Precariousness and the Disparities of Health for the Centers of Examination of Health).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of FTY720 in Patients Who Receive a Kidney Transplant
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: FTY720 5 mg + reduced-dose Neoral (RDN) + corticosteroids|DRUG: FTY720 2.5 mg + full dose Neoral (FDN) + corticosteroids|DRUG: MMF 2 g + full-dose Neoral (FDN) + corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Effectiveness of Rehabilitation Nursing for Acute Stroke
Status: COMPLETED
Conditions: Acute Ischemic Stroke|Nursing
Interventions: BEHAVIORAL: The modified Barthel Index-based rehabilitation nursing program|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Salvage Cryotherapy for Recurrent Prostate Cancer After Radiation Therapy
Status: RECRUITING
Conditions: Prostate Cancer|Cryotherapy|Recurrent Prostate Cancer
Interventions: PROCEDURE: Salvage cryoablation of the prostate (SCAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EEG - Guided Anesthetic Care and Postoperative Delirium
Status: COMPLETED
Conditions: Delirium|Emergence Delirium|Anesthesia, General|Electroencephalography|Laparoscopy|Surgical Procedures, Operative
Interventions: DEVICE: Anesthetic "depth" management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Examine the Effects of Minocycline Extended-Release Tablets on Sperm Production in Human Males.
Status: COMPLETED
Conditions: Human Volunteer
Interventions: DRUG: minocycline extended release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Evaluation of Mouth Wash(Glister Mouth Wash): Pilot Study
Status: COMPLETED
Conditions: Oral Hygiene|Gingival Index|Cetylpyridinium Chloride
Interventions: OTHER: mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Performance and Long-term Safety of FlowOx2.0™, Multiple Sclerosis, Spasticity and Pain
Status: ENROLLING_BY_INVITATION
Conditions: Multiple Sclerosis|Spasticity, Muscle|Pain
Interventions: DEVICE: FlowOx 2.0
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Occlusal Caries Using Silver Modified Atraumatic Restorative Treatment Versus Atraumatic Restorative Treatment
Status: UNKNOWN
Conditions: Occlusal Caries
Interventions: DRUG: Silver modified atraumatic restorative treatment|OTHER: Atraumatic restorative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eat2beNICE Vitamins and Nutrients as Supplementation for Impulsivity, Irritability, and Compulsivity
Status: UNKNOWN
Conditions: Impulsive Behavior
Interventions: OTHER: broad-spectrum micronutrient|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and Tocilizumab for Relapsed Hematological Malignancy Post-allogeneic Transplant
Status: TERMINATED
Conditions: Acute Leukemia|Chronic Leukemia|Lymphoma|Myelodysplastic Syndromes
Interventions: DRUG: Nivolumab (.25 mg/kg)|DRUG: Tocilizumab|DRUG: Nivolumab (.5 mg/kg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Quadrivalent Influenza Vaccine GSK2282512A When Administered to Children 6 to 35 Months of Age
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Quadrivalent influenza GSK2282512A vaccine|BIOLOGICAL: Fluarix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pain Perception: on Relationships Between Dental Anxiety and Olfaction
Status: COMPLETED
Conditions: Dental Anxiety|Dental Pain|Essential Oil
Interventions: OTHER: Aromatherapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Double-blind, Placebo Controlled, Multi-center Study to Evaluate the Safety, Tolerability and Potential Effects of the Dietary Supplement Violet™ Molecular Iodine (I2) on Breast Health in Women With Cyclic Breast Discomfort and Tenderness
Status: COMPLETED
Conditions: Fibrocystic Breast Condition (FBC)
Interventions: DIETARY_SUPPLEMENT: Violet™ Molecular Iodine (I2)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Progesterone and Cervical Pessary in Twins
Status: UNKNOWN
Conditions: Preterm Birth|Twin Pregnancy With Antenatal Problem
Interventions: DEVICE: Arabin Pessary|DRUG: Vaginal Progesterone|OTHER: Arabin Pessary and Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Restoration of Cognitive Function With TDCS and Training in Serious Mental Illness
Status: COMPLETED
Conditions: Schizophrenia|Bipolar Disorder|Schizo Affective Disorder
Interventions: DEVICE: TDCS|DEVICE: Sham Stimulation|BEHAVIORAL: Cognitive Remediation|BEHAVIORAL: Bridging Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tramadol Versus Placebo and Morphine in the Management of Post-Operative Pain Abdominoplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain Management
Interventions: DRUG: Tramadol|DRUG: Morphine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Employee Health Promotion Course on Health Promotion in the Work Place.
Status: ACTIVE_NOT_RECRUITING
Conditions: Lifestyle Risk Reduction|Health Knowledge, Attitudes, Practice|Empowerment
Interventions: BEHAVIORAL: Health Promotion Training for Women Employees
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Normative Brain Volume Profiles From Multicenter Fetal MRI
Status: NOT_YET_RECRUITING
Conditions: Cortical Development Malformation|Multiparametric Magnetic Resonnance Imaging|Brain Cortical Thickness|Prenatal Diagnosis|Fetal Development
Interventions: OTHER: Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Safety and Efficacy of Ruxolitinib Cream for Non-Sclerotic Chronic Cutaneous Graft-Versus-Host Disease
Status: COMPLETED
Conditions: Non-sclerotic Cutaneous Chronic Graft-versus-host Disease
Interventions: DRUG: topical ruxolitinib 1.5% cream|OTHER: Topical vehicle/moisturizer cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study Of Intravenous Metronidazole For Intrabdominal Infection
Status: COMPLETED
Conditions: Intra-abdominal Infections
Interventions: DRUG: Metronidazole|DRUG: Ceftriaxone sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Spirulina on Postprandial Glycemic Responses and Arterial Blood Pressure
Status: COMPLETED
Conditions: Potential Abnormality of Glucose Tolerance|Appetitive Behavior|Blood Pressure
Interventions: OTHER: Glucose as reference food|OTHER: Beverage containing 4g spirulina|OTHER: Beverage containing 6g spirulina|OTHER: Beverage containing 8g spirulina
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study of Galiximab + Rituximab Versus Rituximab + Placebo in Follicular Non-Hodgkin's Lymphoma (NHL)
Status: TERMINATED
Conditions: Lymphoma, Non-Hodgkin's
Interventions: DRUG: Galiximab in combination with rituximab|DRUG: Rituximab in combination with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oligoantigenic Diet and Core Symptomatology of Children With Attention-Deficit /Hyperactivity Disorder (ADHD).
Status: NOT_YET_RECRUITING
Conditions: Attention Deficit Disorder
Interventions: DIETARY_SUPPLEMENT: oligoantigenic diet|OTHER: Food regimen without food restrictions.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ultrasonography for Prediction of Difficult Intubation and Prediction of Endotracheal Tube Size
Status: UNKNOWN
Conditions: Intubation; Difficult or Failed
Interventions: DEVICE: Ultrasonography|DRUG: Sevoflurane|DRUG: intravenous midazolam|DRUG: Propofol|DRUG: fentanyl and rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioavailability of BIBR 953 ZW After Oral Administration of BIBR 1048 MS in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBR 1048 MS Capsule E|DRUG: BIBR 1048 MS Capsule F|DRUG: BIBR 1048 MS Capsule G|DRUG: BIBR 1048 MS Tablet H|DRUG: BIBR 1048 MS Drinking solution|DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemoradiotherapy Combination With Anlotinib for Unresectable Stage III NSCLC Patients
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Anlotinib|OTHER: Concurrent Chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incretin and CRTd.
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Heart Failure
Interventions: DRUG: Incretin Effect|DEVICE: Cardiac Resynchronization therapy defibrillator device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Curative Effect and Mechanism of Transcutaneous Auricular Vagus Nerve Stimulation on Non-motor Symptoms of PD
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Transcutaneous auricular vagus nerve stimulation (real stimulation)|DEVICE: Transcutaneous auricular vagus nerve stimulation (sham stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultra-Brief Versus Brief Hands Only CPR Video Training With and Without Psychomotor Skill Practice
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: BEHAVIORAL: No training, assessed within 60 mins|BEHAVIORAL: Ultra-brief video; assessed in 60 mins|BEHAVIORAL: Brief video; assessed in 60 mins|BEHAVIORAL: Brief video + hands-on; ass'd in 60 mins|BEHAVIORAL: Ultra-brief video; assessed at 2 months|BEHAVIORAL: Brief video; assessed 2 months later|BEHAVIORAL: Brief video + hands-on; ass'd 2 ms later
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Application of Perioperative Remote Ischemic Conditioning in Patients Undergoing Hepatectomy
Status: COMPLETED
Conditions: Hepatic Hemangioma|Liver Cancer|Hepatolithiasis|Hepatectomy
Interventions: DEVICE: Sham-Remote Ischemic Conditioning|DEVICE: Remote Ischemic Conditioning Once Daily|DEVICE: Remote Ischemic Conditioning Twice Daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness Research for Eliminating Disparities
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Engagement and Counseling for Latinos (ECLA-F)|BEHAVIORAL: Engagement and Counseling for Latinos (ECLA-T)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Administration of Oral Carbohydrate Drink and Postoperative Insulin Resistance
Status: COMPLETED
Conditions: Insulin Resistance|Inflammatory Response|Exaggerated Well-Being|Length of Stay
Interventions: DIETARY_SUPPLEMENT: preoperative nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of RENEWAL 4 AVT
Status: COMPLETED
Conditions: Heart Failure|Tachycardia|Atrial Fibrillation|Atrial Flutter|Ventricular Fibrillation
Interventions: DEVICE: CRT-D
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 5 Fractions of Pelvic SABR With Intra Prostatic SABR
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: RADIATION: Pelvic SABR with intra-prostatic SABR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Furosemide Stress Test Predicting Early Graft Function in Kidney Transplantation
Status: RECRUITING
Conditions: Kidney Function|Kidney Transplant; Complications|Delayed Graft Function
Interventions: DRUG: Furosemide Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BIP48 (Peginterferon Alfa 2b 48kDa) Compared With Pegasys® (Peginterferon 2a 40kDa) for Treatment of Chronic Hepatitis C
Status: UNKNOWN
Conditions: Chronic Hepatitis C
Interventions: DRUG: BIP 48 (Peginterferon alfa 2b 48kDA)|DRUG: Peginterferon alfa 2a 40kDA|DRUG: BIP 48 (Peginterferon alfa 2b 48kDA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab Combined With Chemotherapy and Stereotactic Body Radiotherapy (SBRT) in Patients With Oligometastatic Non-small Cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Durvalumab|DRUG: the first line chemotherapy for metastatic NSCLC|RADIATION: stereotactic body radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-flow Nasal Oxygenation Versus Standard Oxygenation for Gastrointestinal Endoscopy With Sedation in Obese Patients
Status: NOT_YET_RECRUITING
Conditions: Prevention of Intraoperative Hypoxia
Interventions: DEVICE: High flow nasal cannula (HFNO)|DEVICE: nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Resistance Training on Pain, Function and Work Ability in Patients With Moderate to Severe Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: BEHAVIORAL: High-intensity resistance training|BEHAVIORAL: General physical activity|BEHAVIORAL: Multidisciplinary rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Phase 3, Randomized Trial of Sequencial Chemoradiotherapy With or Without Toripalimab (PD-1 Antibody) in Newly Diagnosed Early-Stage Extranodal Natural Killer/T Cell Lymphoma, Nasal Type (ENKTL)
Status: RECRUITING
Conditions: NK/T Cell Lymphoma Nos
Interventions: DRUG: Toripalimab|DRUG: Pegaspargase|DRUG: Gemcitabine|DRUG: Oxaliplatin|RADIATION: Definitive intensity-modulated radiotherapy (IMRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Ultrasound in the Diagnosis of Acute Thoracic Syndrome in Vaso-occlusive Sickle Cell Crisis
Status: RECRUITING
Conditions: Sickle-Cell Disease Nos With Crisis
Interventions: DIAGNOSTIC_TEST: pulmonary ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetics and Adhesion of Lidocaine Topical System 1.8% Under Conditions of Heat and Exercise
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lidocaine topical system 1.8%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase I Study of Episcleral Celecoxib for Treatment of Macular Edema and Inflammatory Disorders of the Posterior Pole
Status: ACTIVE_NOT_RECRUITING
Conditions: Macula Edema|Radiation Retinopathy|Branch Retinal Vein Occlusion|Epiretinal Membrane|Central Serous Retinopathy With Pit of Optic Disc|Commotio Retinae|Vitritis
Interventions: DRUG: Episcleral Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of EP-101 ( (SUN101) in Subjects With Moderate to Severe Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Placebo|DRUG: EP-101 12.5 mcg|DRUG: EP-101 25 mcg|DRUG: EP-101 50 mcg|DRUG: EP-101 100 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HFAC Stimulation (30-50 Kilohertz) in Healthy Volunteers (High Frequency Alternating Current Stimulation)
Status: UNKNOWN
Conditions: Healthy|Nerve Block|Pain
Interventions: OTHER: High-frequency alternating current stimulation|OTHER: Sham current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Pruritus
Interventions: DRUG: CR845 0.25 mg Oral Tablet|DRUG: CR845 0.5 mg Oral Tablet|DRUG: CR845 1 mg Oral Tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Liagure Safety in Thyroidectomy With Conventional Thyroidectomy
Status: NOT_YET_RECRUITING
Conditions: Ligature; Hemorrhage|Recurrent Laryngeal Nerve Injuries|Hypocalcemia
Interventions: DEVICE: liagsure device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Once-Daily Atomoxetine Hydrochloride in Adults With ADHD Over an Extended Period of Time (6 Months)
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: Atomoxetine Hydrochloride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study: Plant Based Diet to Patients With Rheumatoid Arthritis
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Intervention with 100% plant-based diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: More Singing, Less Swinging - Is Singing Related to Improved Postural Control?
Status: UNKNOWN
Conditions: Healthy Aging|Balance; Distorted|Singing
Interventions: BEHAVIORAL: Balance Conditions|BEHAVIORAL: Singing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Enteral Feeding and Splanchnic NIRS Values in Infants With Neonatal Encephalopathy (NE)
Status: COMPLETED
Conditions: Neonatal Encephalopathy
Interventions: PROCEDURE: Enteral Feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sofosbuvir/Ledipasvir and Nitazoxanide for Treatment of COVID-19
Status: COMPLETED
Conditions: COVID
Interventions: DRUG: Sofosbuvir and Ledipasvir|DRUG: Nitazoxanide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Effective Methods for Referral for Smoking Cessation Counseling and High Blood Pressure Follow-up
Status: COMPLETED
Conditions: Hypertension|Smoking Cessation
Interventions: BEHAVIORAL: Referral to primary care physician for hypertension control|BEHAVIORAL: Referral to smoking quit line
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Cetuximab Standard or Dose Escalation in First Line Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Dose escalation of cetuximab|DRUG: Standard first line treatment with cetuximab + Folfiri
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ED50 and ED95 of Remifentanil for Intubation Without NOL Variation
Status: COMPLETED
Conditions: Intubation; Difficult or Failed
Interventions: DRUG: Remifentanil dose 0.5 ug/kg|DRUG: Remifentanil dose 1 ug/kg|DRUG: Remifentanil dose 1.5 ug/kg|DRUG: Remifentanil dose 2 ug/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep Thermography for Diagnosis of Obstructive Sleep Apnea (TERMOAPNEA)
Status: COMPLETED
Conditions: Obstructive Sleep Apnea (OSA)
Interventions: OTHER: Therapeutic decision PSG|OTHER: Therapeutic decision Infrared thermgraphy system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Biopsy Forceps Versus Cold Snare for the Resection of Small Colonic Polyps
Status: COMPLETED
Conditions: Colonic Polyps
Interventions: DEVICE: Jumbo cold forceps polypectomy|DEVICE: Cold snare polypectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Exercise Program on Serum Matrix Metalloproteinases and Functional Status in Women With Postmenopausal Osteoporosis
Status: COMPLETED
Conditions: Influence of Specifically Designed Exercise Program on Serum Matrix Metalloproteinases and Functional Status in Women With Postmenopausal Osteoporosis
Interventions: OTHER: exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vit D3 and Omega 3 in Chemo Induced Neuropathy
Status: UNKNOWN
Conditions: Cancer|Neuropathy
Interventions: DRUG: mammalian Omega 3 Fatty acids|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Efficacy and Safety of Injection With HARA as Compared to Restylane® Lidocaine in Temporary Correction of Nasolabial Folds
Status: UNKNOWN
Conditions: Nasolabial FOLD
Interventions: DEVICE: HARA Filler(Hyaluronic acid Filler)|DEVICE: Restylane® Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Fibrin on Root Coverage of Gingival Recessions
Status: COMPLETED
Conditions: Gingival Recession
Interventions: OTHER: Platelet rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telemedical Assistance in Automatic Titration of Oxygen for Intensive Care Patients
Status: RECRUITING
Conditions: Obesity Hypoventilation Syndrome (OHS)|Chronic Obstructive Lung Disease|Interstitial Lung Disease|Pneumonia
Interventions: DEVICE: PHASE 1 Lowenstein medical BiLevel Prisma 25ST device: withount oxygen support.|DEVICE: PHASE 2. Continous/Bilevel positive airway presure with additional oxygen support by Devilbiss 525 KS oxygen concentrator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Genetic Carbohydrate Maldigestion as a Model to Study Food Hypersensitivity
Status: NOT_YET_RECRUITING
Conditions: Irritable Bowel Syndrome (IBS)|Sucrase Isomaltase Deficiency
Interventions: OTHER: Stool and saliva sample collection|OTHER: Questionnaire completion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preventing Propofol Injection Pain: Prospective Randomized Trial Comparing Propofol Versus Fospropofol
Status: COMPLETED
Conditions: Complication of Injection|Pain
Interventions: DRUG: Fospropofol|DRUG: Propofol/Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Motivational Strategies in Batterer Intervention Programs for Offenders With Alcohol/Drug Abuse Problems (IMP-ADAPs)
Status: RECRUITING
Conditions: Intimate Partner Violence Against Women|Alcohol Abuse|Drug Abuse
Interventions: BEHAVIORAL: SBIP+ ADAPs-IMP|BEHAVIORAL: SBIP+IMP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study Evaluating JCPyV-specific T Cell Therapy for PML
Status: NOT_YET_RECRUITING
Conditions: Progressive Multifocal Leukoencephalopathy
Interventions: BIOLOGICAL: CE-VST01-JC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Treatment of Cryoinsufflation in Treatment of Hidradenitis Suppurativa
Status: TERMINATED
Conditions: Hidradenitis Suppurativa
Interventions: OTHER: Cryoinsufflation|OTHER: Deroofing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acids in Treating Patients With Advanced Prostate Cancer
Status: WITHDRAWN
Conditions: Stage III Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: omega-3 fatty acid|OTHER: bone scan|OTHER: dual x-ray absorptometry|OTHER: laboratory biomarker analysis|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acetazolamide Challenge With Perfusion in the Prediction of Cerebral Vasospasm
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage, Aneurysmal|Vasospasm, Cerebral
Interventions: DRUG: Acetazolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study to Compare the Antiviral and Immunologic Effects of Stavudine ( d4T ) Versus Placebo in Subjects With Evidence of Recent HIV Infection.
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Stavudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Transjugular Intrahepatic Portosystemic Shunt (TIPS) for Prevention of Variceal Rebleeding in Cirrhotic Patients With Portal Vein Thrombosis
Status: COMPLETED
Conditions: Decompensated Cirrhosis|Portal Vein Thrombosis|Bleeding Varices
Interventions: PROCEDURE: Transjugular intrahepatic portosystemic shunt (TIPS)|PROCEDURE: ET+NSBB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact on Linkage to HIV Care With Point of Care CD4 Testing and Home-based HIV Testing in Kenya
Status: COMPLETED
Conditions: HIV
Interventions: DEVICE: Point of care CD4 device (Alere PIMA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pilot Study of Neuromodulation for Enhancement of Emotion Regulation in Bipolar Mood Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Bipolar Disorder|Transcranial Magnetic Stimulation
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Service Development: Assessing Non-attendance Rates in Outpatient Clinics
Status: COMPLETED
Conditions: Asthma|Sleep Apnea Syndromes|Tuberculosis|COPD
Interventions: BEHAVIORAL: Telephone reminder call
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH