pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Volumetric Intensity Modulated Arc Therapy vs. Conventional Radiotherapy for Cancer Pain
Status: COMPLETED
Conditions: Neoplasm Metastasis|Pain|Radiotherapy Side Effect|Quality of Life
Interventions: RADIATION: Volumetric Intensity-Modulated Arc Therapy|RADIATION: Conventional Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Serratus Plane Block Versus Thoracic Epidural for Post Thoracotomy Pain
Status: COMPLETED
Conditions: Ultrasound Guided Serratus Plane Block|Thoracic Epidural|Post Thoracotomy Pain
Interventions: PROCEDURE: Serratus anterior block|PROCEDURE: thoracic epidural
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Long-term Oral Staphylococcus Albicans Tablets in Patients With Bronchiectasis
Status: RECRUITING
Conditions: Bronchiectasis
Interventions: DRUG: Staphylococcus and Neisseria Tablets|OTHER: On-demand treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breath, Stress and Health: a Biocultural Study of Hatha Yoga Practice
Status: COMPLETED
Conditions: Stress, Physiological|Stress, Psychological
Interventions: OTHER: High Dose Yoga|OTHER: Medium Dose Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SR-T100 Gel Efficacy & Safety Study for Vulva Pre-cancerous Lesions & Cutaneous Condyloma
Status: COMPLETED
Conditions: Vulvar Intraepithelial Neoplasia|Genital Warts
Interventions: DRUG: SR-T100 gel with 2.3% of SM in Solanum undatum plant extract
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Beneficial Value of PET/CT in the Follow-up of Stage III Non-small Cell Lung Cancer Patients
Status: RECRUITING
Conditions: Stage III Non-small Cell Lung Cancer
Interventions: DIAGNOSTIC_TEST: 18F FDG PET/CT|DIAGNOSTIC_TEST: CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Implant-Abutment Interface Design on Bone and Soft Tissue Levels Around Implants Placed Using Different Transcrestal Sinus Floor Elevation
Status: COMPLETED
Conditions: Tooth Loss
Interventions: DEVICE: Anorganic Bovine Bone Graft Material|DEVICE: Collagen Membrane|DEVICE: Shelta Platform Switching Premium Implants|DEVICE: Shelta Platform Matching Premium Implants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Mavacamten in Participants With HFpEF and Elevation of NT-proBNP With or Without Elevation of cTnT
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: mavacamten
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Postoperative Laxative on Bowel Function After Colonic Surgery
Status: COMPLETED
Conditions: Colonic Cancer
Interventions: DRUG: Magnesia|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy, Safety, and Pharmacokinetics (PK) Study of Ulimorelin in Patients With Enteral Feeding Intolerance (EFI): The PROMOTE Trial
Status: COMPLETED
Conditions: Enteral Feeding Intolerance (EFI)
Interventions: DRUG: Ulimorelin|DRUG: Metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess dHER2+AS15 Cancer Vaccine Given in Combination With Lapatinib to Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: BIOLOGICAL: dHER2 + AS15 ASCI|DRUG: Lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evoluation of Nurses' Skill Training on the Intramuscular Injection With Z Technique in Ventrogluteal Region
Status: ENROLLING_BY_INVITATION
Conditions: Injections
Interventions: OTHER: EDUCATION|OTHER: APPLIED EDUCATION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Feasibility of Partners in Care Program for Caregivers of Patients With Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: BEHAVIORAL: Telephone-Based Intervention|OTHER: Behavioral, Psychological or Informational Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Caffeine, With and Without Biperiden, in the Detoxification of Cocaine Dependent Patients
Status: COMPLETED
Conditions: Cocaine Related Disorders
Interventions: DRUG: Caffeine|DRUG: Biperiden|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Dexmedetomidine Transdermal Systems for Postoperative Analgesia Following Abdominoplasty
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: DMTS Patch|DRUG: Placebo Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Post-operative Effect on Formation of Oedema After Total Knee Arthroplasty With or Without the Use of a Nerve Stimulator (the gekoTM Device)
Status: UNKNOWN
Conditions: Osteoarthritis, Knee|Edema Leg|Joint Diseases|Rehabilitation
Interventions: DEVICE: gekoTM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Plantar Fasciosis Treatment Using Coblation
Status: COMPLETED
Conditions: Plantar Fasciitis
Interventions: DEVICE: ArthroCare TOPAZ™ MicroDebrider™ using Coblation|PROCEDURE: Surgical Fasciotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation (FMT) in Recipients After Allogeneic Hematopoietic Cell Transplantation (HCT)
Status: TERMINATED
Conditions: Allogeneic Hematopoietic Cell Transplantation (HCT)
Interventions: DRUG: FMT|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: "Neutral Head Position" and "Head-lift Position" for Orotracheal Intubation With "Trachway" Intubating Stylet in Adults
Status: COMPLETED
Conditions: Intubation; Difficult
Interventions: PROCEDURE: Head-lift position|DEVICE: 7cm high pillow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab in Treating Patients With Unresectable Nonmetastatic Liver Cancer
Status: COMPLETED
Conditions: Adult Primary Hepatocellular Carcinoma|Localized Unresectable Adult Primary Liver Cancer|Recurrent Adult Primary Liver Cancer
Interventions: BIOLOGICAL: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Efficiency of Modern CT Scanners in Oncologic Scans
Status: UNKNOWN
Conditions: Neoplasms|Neoplasm Metastasis|Metastatic Cancer
Interventions: DIAGNOSTIC_TEST: Scan at CT scanner 1|DIAGNOSTIC_TEST: Scan at CT scanner 2|DIAGNOSTIC_TEST: Scan at CT scanner 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Bioequivalence Study of CT-L01 Compared to Co-administration (ALO 12.5 mg and MET XR 500 mg) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CT-L01 12.5/500 mg|DRUG: Alogliptin Benzoate 12.5 mg|DRUG: Metformin HCl XR 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EverolimuS-ElUtinG BioresorbAble VasculaR Scaffolds vErsus EVerolimus-Eluting Stents in Patients With Diabetes Mellitus
Status: TERMINATED
Conditions: Coronary Artery Disease|Diabetes Mellitus
Interventions: DEVICE: Absorb GT1|DEVICE: Promus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of the Protease Inhibitor Nelfinavir and Concurrent Radiation and Temozolomide in Patients With WHO Grade IV Glioma
Status: COMPLETED
Conditions: Glioma
Interventions: DRUG: Nelfinavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: gemcitabine hydrochloride|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Adaptive Messaging to Support Depression Self-Management
Status: NOT_YET_RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: Adaptive Messaging Intervention|BEHAVIORAL: Non-Adaptive Messaging Intervention|BEHAVIORAL: Psychoeducation-Only Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Elevate Apical and Posterior Prolapse Repair System Compared to Native Tissue Repair for Pelvic Organ Prolapse
Status: TERMINATED
Conditions: Pelvic Organ Prolapse
Interventions: DEVICE: Elevate Apical and Posterior|PROCEDURE: Native Tissue Repair for pelvic organ prolapse
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Safety & Efficacy of ZS (Sodium Zirconium Cyclosilicate)10g qd to Extend Study ZS-004 in Hyperkalemia.
Status: COMPLETED
Conditions: Hyperkalemia
Interventions: DRUG: Sodium Zirconium Cyclosilicate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TReating Incontinence for Underlying Mental and Physical Health
Status: RECRUITING
Conditions: Urinary Incontinence, Urge|Urinary Incontinence|Overactive Bladder|Incontinence, Urge|Incontinence, Urinary|Incontinence
Interventions: DRUG: Tolterodine Tartrate ER|DRUG: Mirabegron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Shiga Toxin Producing Escherichia Coli (STEC) Volume Expansion
Status: WITHDRAWN
Conditions: Hemolytic-Uremic Syndrome
Interventions: DRUG: D5-0.9%NS|DRUG: Routine home oral rehydration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Detection and Classification of Colon Polyps
Status: COMPLETED
Conditions: Colon Polyps
Interventions: PROCEDURE: Polp removal and identification|PROCEDURE: colon polyp removal|PROCEDURE: ETMI colonoscope (ETMI scope is a FDA approved device)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of LY2140023 in Schizophrenia Comparing LY2140023, Olanzapine, and Placebo
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: LY2140023|DRUG: olanzapine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oral Administration of 9-cis Rich Powder of the Alga Dunaliella Bardawil on Visual Functions in Adolescent Patients With Retinitis Pigmentosa
Status: NOT_YET_RECRUITING
Conditions: Retinitis Pigmentosa
Interventions: DIETARY_SUPPLEMENT: Alga Dunaliella Bardawil powder|DIETARY_SUPPLEMENT: Placebo:Starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan in Combination With Cisplatin in Pediatric Patients With Unfavorable Prognosis Gliomas
Status: COMPLETED
Conditions: Pediatric High Risk Gliomas
Interventions: DRUG: Combination of two marketed drugs (irinotecan and cisplatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between HHcy and Contrast-induced Nephropathy in Hypertensive Patients After Coronary Artery Diagnosis and Treatment
Status: COMPLETED
Conditions: Homocysteine|Coronary Disease|Angioplasty,Balloon,Coronary|Contrast Media|Nephropathy|Hypertension
Interventions: DRUG: Enalapril Maleate Tablets(as the program-based antihypertension)|DRUG: Enalapril Maleate and Folic Acid tablets(as the program-based antihypertension)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality and Fear of Falling in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson|Parkinson Disease|Parkinson's Disease and Parkinsonism
Interventions: DIAGNOSTIC_TEST: Virtual reality|DIAGNOSTIC_TEST: Electroencephalogram|DIAGNOSTIC_TEST: Electromyography|DIAGNOSTIC_TEST: Motion Capture system|DIAGNOSTIC_TEST: Polar H10 Heart Sensor|DIAGNOSTIC_TEST: Inertial measurement Unite
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Digital Mental Health and Wellness Intervention for Adults: A Randomized Control Trial of COMET
Status: UNKNOWN
Conditions: Depressive Symptoms|Anxiety
Interventions: OTHER: Common Elements Toolbox- Adult version (COMET-A)|OTHER: Self-awareness Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Calcitriol, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Advanced Solid Tumors That Cannot Be Removed by Surgery
Status: TERMINATED
Conditions: Adult Solid Neoplasm
Interventions: DIETARY_SUPPLEMENT: Calcitriol|DRUG: Cisplatin|DRUG: Gemcitabine Hydrochloride|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Dose Lymph Node Intensity Modulated Radiation Therapy and Hypofractionated Prostate (SIB)
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreous Pegaptanib Sodium Injection in Patients With Exudative Age-Related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: pegaptanib sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide Gene
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Non-Hodgkin's Lymphoma|Myelodysplastic Syndrome|Chronic Myeloid Leukemia
Interventions: BIOLOGICAL: Allodepleted T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closed-loop for People Living With Cystic Fibrosis Related Diabetes
Status: RECRUITING
Conditions: Cystic Fibrosis-related Diabetes
Interventions: DEVICE: CamAPS FX|OTHER: Standard insulin therapy with CGM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Life of Patients With Psoriasis Treated With Methotrexate: Prospective, Randomized, Double-blind, Parallel Group Study.
Status: UNKNOWN
Conditions: Severe Plaque Type Psoriasis
Interventions: DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trametinib in Patients With Advanced Neurofibromatosis Type 1 (NF1)-Mutant Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Helicobacter Rescue Therapy With High-dose Esomeprazole and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy
Status: COMPLETED
Conditions: Gastritis|Dyspepsia|Helicobacter Pylori Infection|Gastric Cancer|Peptic Ulcer
Interventions: DRUG: Esomeprazole|DRUG: Amoxicillin|DRUG: Bismuth|DRUG: Esomeprazole|DRUG: Tetracycline|DRUG: Furazolidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Somatostatin Analogue SOM230 (Pasireotide) in Healthy Male Volunteers
Status: COMPLETED
Conditions: Hyperglycemia
Interventions: DRUG: pasireotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laryngeal Mask Airway as a Bridge for Intubation of Obese Patients for Sleeve Gastrectomy
Status: COMPLETED
Conditions: Bariatric Surgery Candidate
Interventions: DEVICE: Laryngeal mask airway|DEVICE: face mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of PROCHYMAL® Adult Human Stem Cells for Treatment-resistant Moderate-to-severe Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Prochymal®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ictal SPECT With Intra-arterial Injection
Status: WITHDRAWN
Conditions: Epilepsy
Interventions: PROCEDURE: intra-arterial injection of tracer|DRUG: 99m-Technetium Ethyl Cysteinate Dimer|DEVICE: intra-arterial catheter|DEVICE: pressure injector
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Pembrolizumab (MK-3475) Subcutaneous (SC) Versus Pembrolizumab Intravenous (IV) Administered With Platinum Doublet Chemotherapy in Participants With Metastatic Squamous or Nonsquamous Non-Small Cell Lung Cancer (NSCLC) (MK-3475-A86)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: BIOLOGICAL: Pembrolizumab SC|BIOLOGICAL: Pembrolizumab IV|DRUG: Paclitaxel|DRUG: Nab-Paclitaxel|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Immediate Skin-to-Skin Contact After Vaginal Birth in Vigorous Late-Preterm Neonates
Status: TERMINATED
Conditions: Safety Issues
Interventions: OTHER: Skin Group|OTHER: Warmer Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Characterization of LV Strain Patterns in Mildly Elevated PCWP and PAH.
Status: COMPLETED
Conditions: Hypertension, Pulmonary Artery|Ventricular Dysfunction, Left
Interventions: DRUG: sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SB17170 Phase1 Trial in Healthy Volunteer
Status: COMPLETED
Conditions: Safety Issues|Tolerability|Pharmacokinetics|Pharmacodynamics
Interventions: DRUG: SB17170|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Defining the Electrocardiographic Effect of Propofol on the Ajmaline Provocation Drug Challenge: A Prospective Trial
Status: UNKNOWN
Conditions: Brugada Syndrome|Channelopathies|Ventricular Fibrillation|Cardiac Death
Interventions: DRUG: Ajmaline
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Lithium and Valproate in Treating High-Risk Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Lithium|DRUG: Valproic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial Testing the Safety and Tolerability of Chemoradiation Followed by Chemotherapy + Dostarlimab for Stage IIIC, Node Positive, Endometrial Cancer
Status: RECRUITING
Conditions: Endometrial Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Dostarlimab|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation and Adebrelimab in Prostate Cancer With Imaging-measurable Disease (RAPID)
Status: RECRUITING
Conditions: Prostate Cancer Metastatic|Castration-resistant Prostate Cancer
Interventions: RADIATION: Stereotactic body radiotherapy|DRUG: Adebrelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tagraxofusp and Decitabine for the Treatment of Chronic Myelomonocytic Leukemia
Status: RECRUITING
Conditions: Chronic Myelomonocytic Leukemia|Chronic Myelomonocytic Leukemia-1|Chronic Myelomonocytic Leukemia-2|Myelodysplastic/Myeloproliferative Neoplasm
Interventions: DRUG: Decitabine|BIOLOGICAL: Tagraxofusp-erzs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supporting Caregivers of Persons With Dementia: A Pilot Study
Status: COMPLETED
Conditions: Alzheimer Disease|Dementia
Interventions: BEHAVIORAL: Education Control|BEHAVIORAL: Environmental Skill Building
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate The Effects Of a Multivitamin/Mineral With Ginko In Subjects With Age Associated Memory Impairment
Status: COMPLETED
Conditions: Age-Related Memory Disorders
Interventions: DIETARY_SUPPLEMENT: Multivitamin/Multimineral/Ginkgo (BAY 81-2775)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Mechanical Ventilation Guided by Transpulmonary Pressure on Gas Exchange During Robotic Surgery: a Pilot Study
Status: COMPLETED
Conditions: Artificial Respiration|Surgery|Atelectasis
Interventions: PROCEDURE: Transpulmonary pressure driven ventilation strategy|PROCEDURE: Conventional ventilation strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Surgeons' Satisfaction With Two Types of Tinted Chlorhexidine Applicators (Chloraprep® and Nex Clorex 2%)
Status: UNKNOWN
Conditions: Satisfaction|Product Quality
Interventions: OTHER: Surgical tinted Chloraprep® applicators|OTHER: Surgical tinted Nex Clorex 2% applicators
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Z650 in Advanced Esophageal Squamous Cell Carcinoma With EGFR Over Expression or Gene Amplification
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Z650
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Knee Biofeedback Rehabilitation Interface for Game-based Home Therapy for Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: OTHER: KneeBright Group|OTHER: Standard Rehabilitation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CMP-001 and Pre-operative Stereotactic Body Radiation Therapy (SBRT) in Early Stage Triple Negative Breast Cancer (TNBC)
Status: RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: RADIATION: stereotactic body radiotherapy|DRUG: CMP-001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Velaglucerase Alfa (VPRIV) in Chinese Children, Teenagers, and Adults With Type 1 Gaucher Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Gaucher Disease
Interventions: DRUG: Velaglucerase Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nurse Practitioner (NP-led) Care Upon Mood in People With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Nurse's Role
Interventions: OTHER: Nurse Practitioner (NP) Led Care Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nasotracheal Intubation in Children for Outpatient Dental Surgery
Status: COMPLETED
Conditions: Nasotracheal Intubation
Interventions: DEVICE: Direct laryngoscopy and fiberoptic bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Efficacy of Two Supraglottic Airway Devices: I-gel and the Self-pressurized Air-q in Elderly Patients
Status: COMPLETED
Conditions: Supraglottic Airway Devices
Interventions: DEVICE: I-gel|DEVICE: Self-pressurized air-Q
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Viome's Precision Nutrition Program Towards Reducing HbA1c
Status: RECRUITING
Conditions: Diabetes
Interventions: DIETARY_SUPPLEMENT: Viome's Precision Nutrition Program (VPNP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of the MALT1 Inhibitor JNJ-67856633 and Ibrutinib in Combination in B-cell NHL and CLL
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell|Lymphoma, Non-Hodgkin
Interventions: DRUG: JNJ-67856633|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electronic Monitoring of Medication Adherence in Moderate to Severe Asthma Patients
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: Electronic sensor and OW education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Combining Yoga to TENS on Diabetic Glaucoma
Status: UNKNOWN
Conditions: Diabetes Mellitus|Glaucoma
Interventions: DEVICE: active TENS|DEVICE: sham TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Healthy Volunteer Solid Oral Dose and Multiple Ascending Dose Evaluation of CTP-656
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CTP-656|DRUG: Placebo for CTP-656|DRUG: Kalydeco
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I/II Randomized Study of Hydroxyurea With or Without Clotrimazole in Patients With Sickle Cell Anemia
Status: COMPLETED
Conditions: Sickle Cell Anemia
Interventions: DRUG: clotrimazole|DRUG: hydroxyurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of BL-M02D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumors or Other Solid Tumors
Status: RECRUITING
Conditions: Locally Advanced or Metastatic Digestive Tract Tumors|Solid Tumor
Interventions: DRUG: BL-M02D1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Technical Feasibility Study of Ultrasound Muscle Imaging in Antenatal Ultrasound
Status: NOT_YET_RECRUITING
Conditions: Arthrogryposis Multiplex Congenita (AMC)
Interventions: DIAGNOSTIC_TEST: ultrasound muscle imaging technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Assessing the Role of "Statin" Therapy and Perioperative Inflammatory Response in Patients Undergoing Major Orthopedic Surgery
Status: COMPLETED
Conditions: Perioperative Inflammatory Response
Interventions: DRUG: Simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Vilazodone in Adolescent Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Placebo|DRUG: Vilazodone|DRUG: Vilazodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radical Prostatectomy Without Prostate Biopsy Following PSMA PET/CT Based on Diagnostic Model
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: 18F-PSMA-1007 PET/CT based on diagnostic model
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Expanded Natural Killer Cells Following Haploidentical HSCT for AML/MDS
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: OTHER: NK-DLI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melatonin fOr CHronic bAck Pain (The MOCHA Trial)
Status: NOT_YET_RECRUITING
Conditions: Back Pain Lower Back Chronic|Insomnia
Interventions: DRUG: Melatonin 10 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endovascular Stenting Treatment for Patients With Internal Jugular Vein Stenosis
Status: UNKNOWN
Conditions: Stent Stenosis|Intracranial Hypertension|Headache|Tinnitus|Papilledema|Visual Impairment
Interventions: PROCEDURE: Venous stenting for internal jugular vein stenosis|PROCEDURE: One-month routine medical treatment followed by venous stenting for internal jugular vein stenosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Research Study to Evaluate Safety, Tolerability, and Pharmacokinetics of WVE-006 in Healthy Participants With Wild-type AAT Expression (RestorAATion-1)
Status: RECRUITING
Conditions: Alpha-1 Antitrypsin Deficiency
Interventions: DRUG: WVE-006
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Early Testosterone Gel Administration on Physical Performance in the Critically Ill
Status: RECRUITING
Conditions: Critical Illness
Interventions: DRUG: Androgel Topical Product|DRUG: Placebo|DIAGNOSTIC_TEST: Physical performance|DIAGNOSTIC_TEST: Muscle strength|DIAGNOSTIC_TEST: Muscular mass|DIAGNOSTIC_TEST: Test: Functional status|DIAGNOSTIC_TEST: Oxygen muscular consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Relief for Birth Control Implants Insertion
Status: UNKNOWN
Conditions: Contraception|Lidocaine
Interventions: DRUG: Lidocaine Injectable Product|DRUG: Lidocaine Topical Cream [LMX]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Non Invasive Ventilation in Abdominal Postoperative Period
Status: UNKNOWN
Conditions: Surgery|Trauma to the Abdomen|Acute Respiratory Failure
Interventions: OTHER: Non Invasive ventilation (facial mask and NIV ventilator)|OTHER: Standard oxygen therapy with facial mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Acalabrutinib Versus Chlorambucil Plus Rituximab in Adult Subjects With Previously Untreated Chronic Lymphocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Untreated Chronic Lymphocytic Leukemia
Interventions: DRUG: Acalabrutinib|DRUG: Rituximab|DRUG: Chlorambucil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Interventional Study Assessing the Clinical and Operational Effectiveness of Transitioning From Mircera to Daprodustat for the Treatment of Anemia in End Stage Kidney Disease
Status: COMPLETED
Conditions: Anemia|Renal Insufficiency, Chronic|Renal Anemia
Interventions: DRUG: Daprodustat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Experimental Validation of the Long-term Accuracy of Blood Pressure Measurement Using a Smartwatch
Status: ENROLLING_BY_INVITATION
Conditions: Hypertension|Blood Pressure
Interventions: OTHER: Long-term non-invasive Blood pressure monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Linagliptin (BI 1356) on 24h-glucose Control and Various Biomarkers in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo (linagliptin)|DRUG: Placebo (linagliptin)|DRUG: Sitagliptin|DRUG: Placebo (sitagliptin)|DRUG: Placebo (sitagliptin)|DRUG: Linagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Use of RAD001 as Monotherapy in the Treatment of Neurofibromatosis 1 Related Internal Plexiform Neurofibromas
Status: COMPLETED
Conditions: Neurofibromatosis Type 1|Plexiform Neurofibroma|Neurofibromatoses
Interventions: DRUG: RAD001: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypoxia-based Dose Escalation With Radiochemotherapy in Head and Neck Cancer
Status: UNKNOWN
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: RADIATION: radiochemotherapy with 70 Gy|RADIATION: radiochemotherapy with 77 Gy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mind Your Heart-II
Status: RECRUITING
Conditions: Heart Failure|Cognitive Impairment
Interventions: BEHAVIORAL: Mindfulness Training + Enhanced Usual Care|OTHER: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Valproic Acid (VPA) for Acute Kidney Injury (AKI) in Liver Transplant Patients
Status: WITHDRAWN
Conditions: Acute Kidney Injury|Ischemia Reperfusion Injury
Interventions: DRUG: Valproic acid|DRUG: Isotonic saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Techniques for Placement of Perineural Femoral Catheters.
Status: UNKNOWN
Conditions: Postoperative Pain|Anterior Cruciate Ligament Reconstruction
Interventions: PROCEDURE: Placement of a femoral catheter with the hydrolocalization technique|PROCEDURE: Placement of a femoral neurostimulating catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enoxaparin Metabolism in Reconstructive Surgery Patients
Status: COMPLETED
Conditions: Venous Thromboembolism|Deep Venous Thrombosis|Pulmonary Embolus|Reconstructive Surgery
Interventions: DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of the Effect of Differing Platelet Transfusion Times in Neonates
Status: COMPLETED
Conditions: Thrombocytopenia
Interventions: PROCEDURE: Short platelet transfusion|PROCEDURE: Long platelet transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Community Collaboration to Combat COVID-19 (C-FORWARD)
Status: COMPLETED
Conditions: Coronavirus Infection
Interventions: BEHAVIORAL: Fixed site standard of care testing|BEHAVIORAL: Community-based, mobile van testing|BEHAVIORAL: Self-collected, home-based testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study to Evaluate the Drug-drug Interaction Effect of Omeprazole on the Pharmacokinetics (PK) of AMG 510 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: AMG 510|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Brentuximab Vedotin for Systemic Sclerosis
Status: COMPLETED
Conditions: Diffuse Cutaneous Systemic Sclerosis|Scleroderma|dcSSc
Interventions: BIOLOGICAL: Brentuximab Vedotin|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominus Plane Catheters for Open Inguinal Hernia Repair
Status: COMPLETED
Conditions: Post-Operative Pain
Interventions: PROCEDURE: Transversus Abdominis Plane Block|PROCEDURE: Sham Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanical Dilatation of the Cervix at Elective Caesarean Section to Reduce Post-Operative Blood Loss
Status: COMPLETED
Conditions: Post Operative Hemorrhage
Interventions: PROCEDURE: mechanical dilatation of the cervix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PD-1 Blockade With JS001 Plus Neoadjuvant Chemotherapy for Gastric/Gastroesophageal Junction Cancer
Status: RECRUITING
Conditions: Stomach Neoplasms
Interventions: DRUG: Toripalimab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spontaneous Intracranial Hypotension Treatment "SIHT"
Status: COMPLETED
Conditions: Spontaneous Intracranial Hypotension
Interventions: PROCEDURE: 24 hours Trendelenburg position|PROCEDURE: 24 hours bed rest|PROCEDURE: EBP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Menthol Mouth Rinsing and Performance Responses of Elite Football Referees in the Heat
Status: NOT_YET_RECRUITING
Conditions: Exercise Induced Hyperthermia|Performance Demands of Exercising in the Heat
Interventions: OTHER: Menthol solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Motivational Interviewing in Adolescents With Epilepsy
Status: ENROLLING_BY_INVITATION
Conditions: Pediatric ALL
Interventions: OTHER: The Motivational Interviewing Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Epidural Catheter With or Without Adductor Canal Nerve Block for Postoperative Analgesia Following Total Knee Arthroplasty
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee|Nerve Block
Interventions: DEVICE: Adductor Canal Nerve Block Catheter|DEVICE: Adductor Canal Nerve Block Sham Catheter|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Adjunctive Pimavanserin for the Treatment of Schizophrenia (ENHANCE-1)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Pimavanserin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of HLX208 in Advanced Anaplastic Thyroid Cancer (ATC) With BRAF V600 Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: Anaplastic Thyroid Cancer|ATC
Interventions: DRUG: HLX208
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of The Effects of Nebivolol in Comparison to Atenolol on Wall Shear Stress and Rupture Prone Coronary Plaques
Status: COMPLETED
Conditions: Atherosclerosis|Endothelial Function
Interventions: DRUG: Nebivolol|DRUG: Atenolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regorafenib Plus Pembrolizumab in First Line Systemic Treatment of HCC
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Regorafenib(Stivarga, BAY73-4506)|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind, Placebo-controlled, Sequential Single and Multiple Ascending Doses of YG1699
Status: COMPLETED
Conditions: Diabete Mellitus
Interventions: DRUG: YG1699|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Whole-body Vibration in the Frail Elderly
Status: UNKNOWN
Conditions: Sarcopenia;|Osteoporosis
Interventions: PROCEDURE: WBV training|PROCEDURE: PRT training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Persistence of GlaxoSmithKline (GSK) Biologicals' Havrix® in Healthy Adult Subjects Vaccinated at Infancy Under the Hepatitis A Universal Mass Vaccination (UMV) Program in Israel
Status: WITHDRAWN
Conditions: Hepatitis A
Interventions: BIOLOGICAL: Havrix®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Open Label Study of R788 in the Treatment of Persistent/Chronic Immune Thrombocytopenic Purpura (ITP)
Status: COMPLETED
Conditions: Immune Thrombocytopenic Purpura
Interventions: DRUG: Fostamatinib Disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Xa Activity of Enoxaparin for Prevention of Venous Thromboembolism in Severe Nephrotic Syndrome.
Status: TERMINATED
Conditions: Nephrotic Syndrome
Interventions: DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Early Rehabilitation of COPD Patients in ICU
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease|Acute Respiratory Failure
Interventions: OTHER: No specific intervention, standard therapy serving as a control group, passive mobilization of the legs|OTHER: Electrical stimulation of the thigh|OTHER: Cycloergometer training|OTHER: Electrical stimulation of the thigh and cycloergometer training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Metabolomics to Differentiate the Antihypertensive Effect of Acupuncture From Sham Acupuncture in Hypertensives
Status: COMPLETED
Conditions: Hypertension,Essential
Interventions: DEVICE: Acupuncture|DEVICE: Sham Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial to Assess the Efficacy and Safety of LEO 152020 in Adult Patients With Cholinergic Urticaria
Status: COMPLETED
Conditions: Cholinergic Urticaria
Interventions: DRUG: LEO 152020|DRUG: LEO 152020 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT