pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of a Pembrolizumab-based Organ Preservation Strategy for Locally Advanced Larynx Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma of Larynx
Interventions: DRUG: carboplatin AUC of 6, paclitaxel 175 mg/m2, and pembrolizumab 200 mg, i.v. on day 1, every 21 days for 3 cycles|RADIATION: Concurrent radio-immunotherapy: radiation therapy given concurrently with pembrolizumab 200 mg i.v. on day 1, every 21 days for 3 cycles.|DRUG: Consolidation immunotherapy: pembrolizumab 200 mg i.v. on day 1, every 21 days for 11 doses.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Establish The Benefits Of Using Various Starting Doses Of Atorvastatin On Achievement Of Cholesterol Targets (ACTFAST)
Status: COMPLETED
Conditions: Coronary Arteriosclerosis|Diabetes Mellitus, Type 2|Cerebrovascular Accident|Dyslipidemia|Peripheral Vascular Disease
Interventions: DRUG: Atorvastatin (Lipitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunization With the MAGE-3.A1 Peptide Mixed With the Adjuvant CpG 7909 in Patients With Metastatic Melanoma
Status: TERMINATED
Conditions: Malignant Melanoma
Interventions: BIOLOGICAL: MAGE-3.A1 peptide and CpG 7909
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomised, Single Centre, Double-blind, Two-period, Cross-over Trial in Healthy Subjects Investigating the Bioequivalence Between Subcutaneous Injections of Semaglutide Produced by Two Manufacturing Processes
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fibrinogen as an Alternative to FFP in Aortic Surgery.
Status: COMPLETED
Conditions: Coagulopathy in Patients Having Thoraco-Abdominal Aneurysm Repair
Interventions: BIOLOGICAL: Fibrinogen concentrate|BIOLOGICAL: Fresh Frozen Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Pharmacokinetics and Pharmacodynamics of LY2963016 to Lantus in Healthy Participants
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: LY2963016|DRUG: Lantus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: The Long-Term Treatment of Drug Addiction and Unemployment
Status: COMPLETED
Conditions: Substance Abuse, Intravenous
Interventions: BEHAVIORAL: Abstinence-contingent wage supplements|BEHAVIORAL: Individual Placement and Support (IPS) supported employment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness
Status: COMPLETED
Conditions: Bacteremia|Intensive Care|Critically Ill|Sepsis|Mortality|Antimicrobial
Interventions: OTHER: 7 days of adequate antibiotic treatment|OTHER: 14 days of adequate antibiotic treatment.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypoglycemia Requiring Emergency Services Intervention: Patient Characteristics, Outcome and Cardiovascular Risk Profile
Status: COMPLETED
Conditions: Diabetes Mellitus|Hypoglycemia
Interventions: BEHAVIORAL: Structured nurse led intervention programme|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Early MOtion Total Ankle Artroplasty
Status: RECRUITING
Conditions: Ankle Osteoarthritis|Ankle - Recurrent Dislocation|Cartilage Disease|Ankle Arthropathy
Interventions: PROCEDURE: early mobilizzation of the ankle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial
Status: RECRUITING
Conditions: Intracerebral Haemorrhage (ICH)|Hypertension
Interventions: DRUG: telmisartan 20mg, amlodipine 2.5mg, and indapamide 1.25mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Physician-Initiated Observational Study of The Contact Detection System (CDS) in Patients Undergoing Radiofrequency Ablation Using the Niobe™ Remote Magnetic Navigation System
Status: COMPLETED
Conditions: Atrial Fibrillation|Catheter Ablation
Interventions: DEVICE: CDS box connection of the Niobe™ Remote Magnetic Navigation System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Percutaneous Bilateral Versus Unilateral Metal Stent for Hilar Cholangiocarcinoma
Status: UNKNOWN
Conditions: Hilar Cholangiocarcinoma
Interventions: PROCEDURE: bilateral metal stent insertion|PROCEDURE: unilateral metal stent insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptance and Commitment Therapy in the Treatment of Obesity: Pilot.
Status: WITHDRAWN
Conditions: Obesity, Acceptance and Commitment Therapy, Weight Management Service
Interventions: BEHAVIORAL: Acceptance and commitment therapy|BEHAVIORAL: Treatment as usual (dietetic intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Masayang Pamilya Feasibility Study
Status: COMPLETED
Conditions: Parent-Child Relations|Child Maltreatment|Child Behavior Problem|Parenting
Interventions: BEHAVIORAL: Masayang Pamilya Para Sa Batang Pilipino Program (MaPa Kids)|BEHAVIORAL: Masayang Pamilya Para Sa Tinedyer Pilipino Program (MaPa Teens)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Anti-1-amino-3-[18F]Fluorocyclobutyl-1-carboxylic Acid (Anti-[18F](FACBC)Positron Emission Tomography (PET-CT) of the Breast
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: FACBC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study of the Effect of Dietary Fat Type and Amount on Vitamin D3 Absorption
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: cholecalciferol|DIETARY_SUPPLEMENT: cholecalciferol|DIETARY_SUPPLEMENT: cholecalciferol|DIETARY_SUPPLEMENT: cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Ocular Hypertension
Interventions: DRUG: brimonidine/timolol fixed combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Tribulus Terrestris on Sexual Function in Post-menopausal Women
Status: COMPLETED
Conditions: Sexual Functions and Problems in the Adult
Interventions: DRUG: Placebo|DRUG: Tribulus terrestris
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Guidance Videos to Increase Engagement and Decrease Anxiety in Patients Undergoing Pleural Tap
Status: UNKNOWN
Conditions: Pleural Effusion|Pleural Effusion, Malignant|Pleural Pleurisy Effusion
Interventions: OTHER: Personalized training video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Clinical Study of Pitavastatin Treatment for Group of Mild to Moderate Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer Disease|Hypercholesterolemia
Interventions: DRUG: Pitavastatin|DRUG: cholesterol-lowering medicine other than statin(e.g.,Ezetimibe,Colestimide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Renal Impairment on the Pharmacokinetics of Oral Treprostinil
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension|Renal Dysfunction
Interventions: DRUG: UT-15C SR (treprostinil diethanolamine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser-Mediated Photodynamic Therapy of Acne Vulgaris and Rosacea
Status: COMPLETED
Conditions: Acne Vulgaris and Rosacea
Interventions: DEVICE: Long-pulsed dye laser (Candela) and PDT (methylaminolevulinate)|DEVICE: Long-pulsed dye laser|DEVICE: Long-pulsed dye laser assisted fotodynamic therapy (methylaminolevulinate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose:
Clinical trial: MAGE-A3 Protein + AS15 as Consolidation for Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: recMAGE-A3 Protein + AS15 Adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Castration on the Pharmacokinetics of Zolpidem After Single Dose Administration In Men With Prostate Cancer Undergoing Androgen Deprivation Therapy Compared to Normal Healthy Females
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Zolpidem
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Maintenance at Initial Treatment With Sequential Anti-Inflammation Reliever Therapy
Status: NOT_YET_RECRUITING
Conditions: Bronchial Asthma
Interventions: DRUG: Maintenance at initial treatment sequential as-needed therapy with inhaled budesonide-formoterol(Symbicort 160/4.5) ®）|DRUG: as-needed therapy with inhaled budesonide-formoterol (Symbicort 160/4.5) ®）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CalFitness Smartphone-Delivered Physical Activity Intervention With Messaging
Status: COMPLETED
Conditions: Sedentary Lifestyle|Physical Activity
Interventions: BEHAVIORAL: Step Goal Delivery by Smartphone|BEHAVIORAL: Message Delivery by Smartphone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple-Dose Study to Evaluate Skin Irritation and Sensitization of Teriparatide Administered Transdermally in Healthy Postmenopausal Women
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: LY333334|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation Versus Long-term Nicotine Replacement Among High-risk Smokers
Status: COMPLETED
Conditions: Smoking|Pulmonary Disease, Chronic Obstructive|Tobacco Use Disorder
Interventions: OTHER: Standard Smoking Cessation|OTHER: Extended Nicotine Replacement Therapy|DRUG: Nicotine replacement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telemedicine Program in Type 1 Diabetes and CSII
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: OTHER: Group 2a. Telemedicine program|OTHER: Group 1a. Control|OTHER: Group 1b.Telemedicine program|OTHER: Group 2b. Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess Safety, Reactogenicity & Immunogenicity of 2 Doses of GSK's Oral Human Rotavirus Vaccine in Pre-Term Infants
Status: COMPLETED
Conditions: Infections, Rotavirus
Interventions: BIOLOGICAL: Rotarix™|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neurofeedback for Obsessive-Compulsive Disorder (OCD)
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: neurofeedback|BEHAVIORAL: control feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Sirolimus With Cyclosporine in a Calcineurin Inhibitor (CNI)-Free Regimen in Kidney Transplant Recipients
Status: TERMINATED
Conditions: Kidney Transplant
Interventions: DRUG: sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Human Albumin Supplementation on Kidney Dysfunction After Liver Transplantation
Status: NOT_YET_RECRUITING
Conditions: Liver Transplantation|Acute Kidney Injury
Interventions: DRUG: Albumin administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Application of Tranexamic Acid to Reduce Post-operative Bleeding in Coronary Artery Bypass Surgery
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Tranexamic Acid|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Controlled Trial of an Incentive-based Physical Activity Program Targeting Both Children and Adults (FIT-FAM)
Status: COMPLETED
Conditions: Physical Activity
Interventions: DEVICE: Fitbit|BEHAVIORAL: Incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Chemotherapy With XELOX (Oxaliplatin + Capecitabine) and Bevacizumab in Combination With Adebrelimab in First-line Treatment of Microsatellite Stable (MSS) Initially Unresectable Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Adebrelimab|DRUG: Oxaliplatin|DRUG: Capecitabine|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TPM Regimen (Thalidomide, Prednisone and Methotrexate) in LGLL
Status: RECRUITING
Conditions: T-LGL Leukemia|Clpd-Nk
Interventions: DRUG: thalidomide + prednisone + methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetic Macular Edema and Diabetic Retinopathy Screening (TeleMed) With Automated Retinal Photography
Status: UNKNOWN
Conditions: Mild Nonproliferative Diabetic Retinopathy|Moderate Nonproliferative Diabetic Retinopathy|Severe Nonproliferative Diabetic Retinopathy|Proliferative Diabetic Retinopathy|Diabetic Macular Edema
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mercaptopurine Therapy in Ulcerative Colitis
Status: UNKNOWN
Conditions: Colitis, Ulcerative
Interventions: DRUG: Mercaptopurine (Purinethol)|DRUG: Placebo|DRUG: Mesalamine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy of EEG-guided Magnetic Resonant Therapy in War Veterans With Posttraumatic Stress Disorder
Status: TERMINATED
Conditions: Post-Traumatic Stress Disorders
Interventions: DEVICE: individualized Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Blood Carboxyhemoglobin Levels on Total Antioxidant (Tas), Total Oxidant(Tos), Hypoxia Inducible Factor-1a (hif1a) During Low-flow and Normal-flow Anesthesia
Status: COMPLETED
Conditions: Carbon Monoxide Exposure
Interventions: PROCEDURE: low-flow anesthesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Active You: Feasibility of a Unique Physical Activity Program to Prevent Diabetes and Heart Disease
Status: COMPLETED
Conditions: Cardiovascular Risk Factor|Prediabetes|Overweight and Obesity|Sedentary Behavior
Interventions: BEHAVIORAL: The Physical Activity for The Heart (PATH) intervention|BEHAVIORAL: Be Active Your Way Booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Drinking Beetroot Juice on Exercise Performance in Patients With Fibrotic Interstitial Lung Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Interstitial Lung Disease
Interventions: DIETARY_SUPPLEMENT: concentrated beetroot juice (400mg of nitrate per serving)|DIETARY_SUPPLEMENT: concentrated beetroot juice (trace amounts of nitrate per serving)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: WATCHMAN Left Atrial Appendage System for Embolic PROTECTion in Patients With Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Stroke
Interventions: DEVICE: WATCHMAN Left Atrial Appendage Closure Technology|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cabozantinib (XL-184) Monotherapy for Advanced Cholangiocarcinoma
Status: COMPLETED
Conditions: Bile Duct Cancer|Intrahepatic Cholangiocarcinoma|Cholangiocarcinoma of the Extrahepatic Bile Duct
Interventions: DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cervix Cytological Screening - Comparison of Tampon Self-Test and the Routine Smear.
Status: COMPLETED
Conditions: Uterine Cervical Dysplasia|Uterine Cervical Neoplasms
Interventions: PROCEDURE: Regular Tampax used in 3 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: SCREENING
Clinical trial: Fulvestrant Plus Abemaciclib in Women With Advanced Low Grade Serous Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Neoplasms of Female Genital Organs
Interventions: DRUG: Fulvestrant|DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Forced Oscillometry in Infants With Bronchopulmonary Dysplasia
Status: RECRUITING
Conditions: Infant, Premature, Diseases|Bronchopulmonary Dysplasia|Respiratory Distress Syndrome
Interventions: DEVICE: Non-invasive forced airway oscillometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intra-Anally Administered Artesunate in Patients With High-Grade Anal Intraepithelial Neoplasia (AIN 2/3)
Status: COMPLETED
Conditions: HPV-Related Anal Intraepithelial Neoplasia|AIN2/3|Artesunate|Alternative Treatment|Anal Dysplasia|Precancerous Conditions|Human Papilloma Virus
Interventions: DRUG: Artesunate Suppositories
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Randomised Multicenter Phase 3b Study to Determine the Confirmed Rate of Molecular Response ≥ 4 Log (MR4) at Two Years
Status: TERMINATED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Imatinib|DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Plasma Infusion Therapy for Congenital Thrombotic Thrombocytopenic Purpura
Status: WITHDRAWN
Conditions: Purpura, Thrombotic Thrombocytopenic
Interventions: DRUG: Octaplas infusion and placebo (group 1)|DRUG: Octaplas infusion and placebo (group 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Wilm's Tumor 1 (WT1) Peptide Vaccine for High Risk Hematologic Malignancy
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Acute Myeloid Leukemia (AML)|Chronic Myeloid Leukemia (CML)
Interventions: DRUG: WT1 Peptide Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ischemic Postconditioning in STEMI Patients Treated With Primary PCI
Status: RECRUITING
Conditions: ST Segment Elevation Myocardial Infarction
Interventions: PROCEDURE: Ischemic postconditioning|PROCEDURE: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Bridge™ Device to Treat Opioid Withdrawal Symptoms
Status: ENROLLING_BY_INVITATION
Conditions: Opioid Use Disorder
Interventions: DEVICE: Bridge™ active device|DEVICE: Bridge™ sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the echOpen Device to Detect Pyelocaliceal Dilation and Hepatic Steatosis
Status: COMPLETED
Conditions: Hepatic Steatosis|Fatty Liver|Hydronephrosis
Interventions: DEVICE: EchOpen ultra-portable ultrasound device|DEVICE: Ultrasound device routinely used in the department|PROCEDURE: Ultrasound examination by an independent referent radiologist
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Trial to Evaluate the Effects of Rotigotine Transdermal Patch on Early Morning Motor Impairment and Sleep Disorders Idiopathic Parkinson's Disease
Status: COMPLETED
Conditions: IDIOPATHIC PARKINSON'S DISEASE
Interventions: DRUG: Rotigotine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Evorpacept (ALX148) With Enfortumab Vedotin for Subjects With Urothelial Carcinoma (ASPEN-07)
Status: RECRUITING
Conditions: Bladder Cancer|Urothelial Carcinoma
Interventions: DRUG: Evorpacept|DRUG: Enfortumab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of GRA in Patients With Type 1
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 1 Diabetes
Interventions: DRUG: REMD-477|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: CardioPulmonary Resuscitation With Argon (CPAr) Trial
Status: RECRUITING
Conditions: Cardiac Arrest, Out-Of-Hospital|Cardiac Arrest With Successful Resuscitation
Interventions: OTHER: Noble gas Argon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Postoperative Nausea and Vomiting After Bariatric Surgery
Status: UNKNOWN
Conditions: Bariatric Surgery Candidate|Postoperative Nausea and Vomiting|Morbid Obesity
Interventions: DIETARY_SUPPLEMENT: Bariatric Full Liquid Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Significance of Impedance Cardiography and Early Repolarization Pattern in ECG in Congestive Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure|Chronic Heart Failure|Right Ventricular Failure|Heart Failure
Interventions: DIAGNOSTIC_TEST: Impedance cardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Conventional Total Hip Arthroplasty vs Mako Robotic-arm Assisted Total Hip Arthroplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Hip|Osteoarthritis|Surgery
Interventions: DEVICE: CO THA|DEVICE: Mako THA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Royal Jelly Supplementation in Chronic Kidney Disease
Status: NOT_YET_RECRUITING
Conditions: Kidney Failure, Chronic|Oxidative Stress|Hemodialysis
Interventions: DIETARY_SUPPLEMENT: Real Jelly|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Internet-delivered Interventions for Stress, Anxiety and Depression in the Workplace
Status: WITHDRAWN
Conditions: Depression|Anxiety|Stress
Interventions: BEHAVIORAL: Space from Depression|BEHAVIORAL: Space from Anxiety|BEHAVIORAL: Space from Stress|BEHAVIORAL: Face-to-face counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Recombinant Hepatitis E Vaccine
Status: COMPLETED
Conditions: Hepatitis E
Interventions: BIOLOGICAL: hepatitis E vaccine|BIOLOGICAL: Hepatitis B vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Proton Radiation for Stage II/III Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Breast Neoplasm|Breast Tumor|Cancer of the Breast
Interventions: RADIATION: Proton Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cystoinflation to Prevent Bladder Injury in Obstetrics and Gynaecology Surgery
Status: COMPLETED
Conditions: Bladder Injury|Complications; Cesarean Section|Adhesions Pelvic
Interventions: PROCEDURE: Cystoinflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Effectiveness of Epoetin Alfa in AIDS Patients With Anemia Caused Both by Their Disease and by AZT (Zidovudine, an Antiviral Drug) Given as Treatment for Their Disease
Status: COMPLETED
Conditions: Anemia|Acquired Immunodeficiency Syndrome
Interventions: DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of GSK2849330 in Subjects With Advanced Her3-Positive Solid Tumors
Status: COMPLETED
Conditions: Cancer|Neoplasms
Interventions: BIOLOGICAL: GSK2849330
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Valsartan on Lipid Subfractions in Hypertensive Patients With Metabolic Syndrome
Status: COMPLETED
Conditions: Hypertension|Metabolic Syndrome
Interventions: DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability Study of Nadolol (1 x 80 mg) Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: High Blood Pressure|Migraine Headaches|Chest Pain
Interventions: DRUG: Nadolol (1 x 80 mg) Tablets (Invamed, Inc)|DRUG: Corgard (1 x 80 mg) Tablets (Bristol Laboratories)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cangrelor to Clopidogrel or Prasugrel Transition Study
Status: COMPLETED
Conditions: Coronary Artery Disease (CAD)
Interventions: DRUG: Cangrelor|DRUG: Clopidogrel|DRUG: Prasugrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating The Efficacy Of A Mind-Body Intervention In Overcoming Opioid Addiction
Status: COMPLETED
Conditions: Opioid Use|Opioid-use Disorder|Substance Use Disorders
Interventions: BEHAVIORAL: Sky Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Patient Perception Between Two Emergency Treatments of Symptomatic Irreversible Pulpitis.
Status: COMPLETED
Conditions: Irreversible Pulpitis
Interventions: PROCEDURE: Pulpotomy|PROCEDURE: Pulpectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study to Test the Benefit of a New Kind of Anti-cancer Treatment in Patients With Melanoma, After Surgical Removal of Their Tumor
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: GSK 2132231A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: F573 for Injection for the Treatment of Liver Injury/Failure
Status: RECRUITING
Conditions: Acute Liver Failure|Acute-On-Chronic Liver Failure
Interventions: DRUG: F573 for injection|DRUG: Sterilizing water for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab in Treating Patients With Bladder Cancer Undergoing Radical Cystectomy
Status: COMPLETED
Conditions: Stage I Bladder Cancer AJCC v8|Stage II Bladder Cancer AJCC v8|Stage III Bladder Cancer AJCC v8|Stage IIIA Bladder Cancer AJCC v8|Stage IIIB Bladder Cancer AJCC v8
Interventions: BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prediction of Postsurgical Symptomatic Outcomes With Preoperative Pessary Use
Status: COMPLETED
Conditions: Vaginal Vault Prolapse|Pelvic Organ Prolapse|Uterine Prolapse|Pelvic Floor Prolapse
Interventions: DEVICE: Preoperative Pessary Use
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy of a 5-day, 10- mg PBF-680 Oral Administration on Late Asthmatic Responses (LAR) in Mild to Moderate Asthmatic Patients.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: PBF-680|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Probiotic Potential of Lactobacillus Strains in the Upper Respiratory Tract After Nasal Spray Application
Status: UNKNOWN
Conditions: Healthy Volunteers|Chronic Rhinosinusitis (Diagnosis)|Probiotics|Sprays|Nasal Disease
Interventions: OTHER: Probiotic nasal spray|OTHER: Placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Determine the Correct Dose of Amikacin Which is Delivered Directly to the Lungs of Ventilated Patients as an Aerosol Via an Investigational Device Called the Pulmonary Delivery Device System (PDDS)
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Amikacin (BAY41-6551)|DRUG: Amikacin (BAY41-6551)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy for the Treatment of Seasonal Affective Disorder (SAD)
Status: COMPLETED
Conditions: Seasonal Affective Disorder|Depression
Interventions: BEHAVIORAL: Light Therapy|BEHAVIORAL: Cognitive behavioral therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Total Neoadjuvant Therapy Versus Standard Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: RADIATION: Radiotherapy|DRUG: consolidation chemotherapy|PROCEDURE: TME or APR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Continuous Saphenous Nerve Block for Total Knee Arthroplasty
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: continuous saphenous nerve block|PROCEDURE: Saline boluses in nerve catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultraslow SWL Versus Slow SWL for Ureteric Stones With High Attenuation Value
Status: COMPLETED
Conditions: Ureteric Stone
Interventions: PROCEDURE: SWL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Daily Sinus Irrigation on Nasal Symptoms in Continuous Positive Airway Pressure (CPAP) Users - A Pilot Study
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: NeilMed nose and sinus irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Drainage After Flexible Ureterorenoscopy; Prospective Assessment of Perioperative Outcomes and Health-Related Quality of Life Through a Randomized Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Stones, Kidney
Interventions: PROCEDURE: Flexible ureteroscopy for renal calculi less than 20 mm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigation of Tendoncel, a Novel Topical Platelet Lysate Gel, in the Treatment of Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: BIOLOGICAL: Tendoncel|OTHER: Placebo control gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Integrity of Down Inhibitor Bundle at Patients Suffering of Neuropathic Pain
Status: COMPLETED
Conditions: Healthy Volunteers|Patients Suffering of Peripheral Neuropathic Pain
Interventions: OTHER: Neuropathic pain
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial Evaluating Dovitinib Combined With Fulvestrant, in Postmenopausal Patients With HER2- and HR+ Breast Cancer
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Dovitinib|DRUG: Fulvestrant|DRUG: Dovitinib Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Adjuvant Hormonal Therapy in Surgically Treated Prostate Cancer Patients at High Risk for Recurrence
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Flutamide|DRUG: Leuprolide Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Finding Trial of Polyethylene Glycol 3350 Laxative Plus Electrolytes for the Treatment of Constipation (Protocol P07515)
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: PEG 3350 laxative plus electrolytes (PEG + E)/Macrogol (Movicol®, BAY81-8430)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plethysmographic Waveform for Monitoring the Quality of Cardiopulmonary Resuscitation
Status: COMPLETED
Conditions: Cardiopulmonary Arrest|Cardiopulmonary Resuscitation|Return of Spontaneous Circulation|Pulse Oximeter Plethysmographic Waveform
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Open-Label, Placebo-Controlled, Parallel Group Study in Healthy Volunteers to Evaluate the Effects of Two Single MT 400 or Naproxen Sodium Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: MT400
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prediabetes Intervention With Tea
Status: ENROLLING_BY_INVITATION
Conditions: Diabetes Mellitus, Type 2|Pre Diabetes
Interventions: OTHER: Olive Leaf Tea|BEHAVIORAL: Lifestyle behavior change program (LBC)|OTHER: Placebo tea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Screening for Colorectal Cancer in Average and High Risk Population
Status: COMPLETED
Conditions: Colorectal Neoplasms|Colorectal Cancer|Adenomatous Polyp of Colon
Interventions: DIAGNOSTIC_TEST: FIT|PROCEDURE: Precolonoscopy cleansing regimen|PROCEDURE: Conventional Colonoscopy|DIAGNOSTIC_TEST: Histopathological examinations of screen-detected lesions|DRUG: Tribenoside 400 mg + lidocaine 40 mg suppositories|DRUG: Diltiazem hydrochloride 2%/Nitroglycerin rectal ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: RCT of AttraX® Putty vs. Autograft in Instrumented Posterolateral Spinal Fusion
Status: COMPLETED
Conditions: Spinal Deformity|Spinal Instability|Instrumented Spinal Fusion
Interventions: DEVICE: AttraX® Putty|OTHER: Autologous bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Assess The Effect Of Linezolid On QTc Interval
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: DRUG: Placebo|DRUG: Linezolid 900 mg|DRUG: Linezolid 1200 mg|DRUG: Placebo|DRUG: Linezolid 600 mg|DRUG: Linezolid 1200 mg|DRUG: Moxifloxacin 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Double-Blind, Multicenter, Study Comparing the Efficacy and Safety of OMS103HP With Vehicle Irrigation Solution in Subjects Undergoing Meniscectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: OMS103HP|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Idelalisib in Japanese Participants With Relapsed or Refractory Indolent B-Cell Non-Hodgkin Lymphomas (iNHL) or Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Indolent Non-Hodgkin Lymphoma|Follicular Lymphoma|Small Lymphocytic Lymphoma|Lymphoplasmacytic Lymphoma (With or Without Waldenstrom Macroglobulinemia)|Marginal Zone Lymphoma
Interventions: DRUG: Idelalisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A One-year, Open Label Study to Investigate the Safety and the Effect of Enteric-coated Mycophenolate Sodium (EC-MPS) in Combination With Cyclosporine Microemulsion in de Novo Kidney Transplant Recipients.
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Enteric-Coated Mycophenolate sodium (EC-MPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety of MB-CART2019.1 in Lymphoma Patients (MB-CART2019.1 Lymphoma / DALY 1)
Status: COMPLETED
Conditions: B-cell Non Hodgkin Lymphoma
Interventions: BIOLOGICAL: MB-CART2019.1 Dose level 1|BIOLOGICAL: MB-CART2019.1 Dose level 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arsenic Trioxide and Ascorbic Acid Combined With Bortezomib, Thalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma or Plasma Cell Leukemia
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DIETARY_SUPPLEMENT: ascorbic acid|DRUG: arsenic trioxide|DRUG: bortezomib|DRUG: dexamethasone|DRUG: thalidomide|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COlchicine in Cardiac Surgery
Status: COMPLETED
Conditions: Colchicine Adverse Reaction|Atrial Fibrillation New Onset
Interventions: DRUG: Colchicine Pill|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Translational Study Investigating Possible Molecular prEdictors of Resistance to First-Line pazopanIb
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Safety and Imaging Study of AI-700 in Patients With Suspected Coronary Artery Disease Undergoing Coronary Angiography
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: AI-700 contrast-enhanced echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Evaluation of Fiber Reinforced Resin Composite Base Versus Incremental Packing of Nanohybrid Resin Composite
Status: COMPLETED
Conditions: Caries Class II
Interventions: DRUG: EverX Posterior|DRUG: Resins, Composite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of AMV564 in Patients With AML
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: AMV564|COMBINATION_PRODUCT: AMV564 in combination with pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Magnetic Therapy on Pain Relief in Postoperation Patients
Status: UNKNOWN
Conditions: Surgical Patients|Hospitalized Patients
Interventions: OTHER: Static magnet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Diagnosis of Cervical Lesions in Women With Unhealthy Looking Cervix
Status: WITHDRAWN
Conditions: Cervical Dysplasia
Interventions: PROCEDURE: 3- Cervical Pap smears|PROCEDURE: Colposcopic examination|PROCEDURE: Office hysteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of IV Fluid Loading and Ondansetron in Reduction of PONV After LC
Status: COMPLETED
Conditions: Postoperative Nausea|Postoperative Vomiting|Postoperative Nausea and Vomiting
Interventions: OTHER: Fluid loading|DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Target Attainment of TDM-guided Infusion of Piperacillin/Tazobactam and Cefepim in Critically Ill Patients
Status: COMPLETED
Conditions: Critical Illness|Antibiotic Toxicity|Sepsis|Septic Shock
Interventions: OTHER: dosage of concentration of piperacillin and cefepim
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Pembrolizumab Plus Fulvestrant in Hormone Receptor Positive, HER-2 Negative Advanced/Metastatic Breast Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The DASH Diet for Adults With Uncontrolled Asthma
Status: COMPLETED
Conditions: Asthma|Hypertension
Interventions: BEHAVIORAL: Dietary Approaches to Stop Hypertension dietary pattern
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Metabolic Outcomes in Patients Receiving Tyrosine Kinase Inhibitor (TKI) Therapy With Dasatinib or Nilotinib
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia (CML)
Interventions: DRUG: dasatinib|DRUG: nilotinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Combination Therapy Strategy to Prevent Anti-PD-1 Therapy Resistance in Metastatic Ovarian Cancer Patients
Status: SUSPENDED
Conditions: Ovarian Cancer Stage IV|Ovarian Cancer Stage III|Ovarian Cancer Stage 3
Interventions: BIOLOGICAL: NY-ESO-1 Peptide vaccine|DRUG: Toripalimab-tpzi
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT