pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Examining Self-tracking Behaviors in a Mobile Intervention for Binge Eating and Weight Management
Status: COMPLETED
Conditions: Obesity|Binge Eating
Interventions: BEHAVIORAL: Track clinician-determined symptoms|BEHAVIORAL: Track clinician-determined and self-determined symptoms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Redesigning Systems to Improve Quality for Hospitalized Patients
Status: COMPLETED
Conditions: Interdisciplinary Communication|Interpersonal Relations|Adverse Event|Interprofessional Relations
Interventions: BEHAVIORAL: Advanced and Integrated MicroSystems (AIMS) interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Innovative Public-private Partnership to Target Subsidized Antimalarials in the Retail Sector
Status: COMPLETED
Conditions: Fever|Malaria
Interventions: OTHER: Free Malaria Rapid Diagnostic Test|OTHER: Conditional ACT voucher|OTHER: Malaria Rapid Diagnostic test for a charge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Anticholinergic Burden in Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder|Delusional Disorder|Psychotic Disorders
Interventions: DRUG: Benztropine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Cycling on Executive Control
Status: COMPLETED
Conditions: Physical Activity
Interventions: BEHAVIORAL: Sitting|BEHAVIORAL: Light-Intensity Cycling|BEHAVIORAL: Moderate-Intensity Cycling|BEHAVIORAL: High-Intensity Cycling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Proleukin in Combination With Rituxan in Patients With Low-Grade Non-Hodgkin's Lymphoma Who Have Previously Failed Rituxan Treatments
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: Recombinant Human Interleukin-2 and Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia
Status: RECRUITING
Conditions: Aging|Menopause|Hypoxia|Vasodilation
Interventions: DRUG: Placebo|DRUG: Propranolol|DRUG: Gemtesa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Investigate the Safety and Effectiveness of Aspheric Laser Refractive Surgery Treatments for Myopia
Status: COMPLETED
Conditions: Myopia|Astigmatism
Interventions: DEVICE: The Bausch & Lomb Zyoptix Tissue Saving Aspheric algorithm|DEVICE: The Bausch & Lomb Zyoptix Tissue Saving algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 4, Single-Blind, Randomized, Study to Compare the Tolerability and Efficacy of 0.1% Tazorac Cream When Used in Combination With Either Duac Gel or Acanya Gel for the Treatment of Facial Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Clindamycin 1%/Benzoyl Peroxide 5% and 0.1% tazarotene|DRUG: clindamycin phosphate 1.2%/benzoyl peroxide 2.5% and 0.1% tazarotene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: UFH is the Most Used Anticoagulant in Hemodialysis, Decreasing the Risk of Clot Formation in the Circuit.
Status: COMPLETED
Conditions: Hemodialysis Complication
Interventions: DRUG: Liquaemin|DRUG: Heptar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Plerixafor After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed High Grade Glioma
Status: COMPLETED
Conditions: Adult Ependymoblastoma|Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Adult Medulloblastoma|Adult Mixed Glioma|Adult Oligodendroglial Tumors|Adult Pineoblastoma|Adult Supratentorial Primitive Neuroectodermal Tumor (PNET)
Interventions: RADIATION: radiation therapy|DRUG: temozolomide|DRUG: plerixafor|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Association Between Pelvic Floor Muscle Function, Diastasis Recti and Postpartum Pelvic Girdle Pain - a Matched Case Control Study.
Status: COMPLETED
Conditions: Pelvic Girdle Pain|Diastasis Recti and Weakness of the Linea Alba|Pelvic Floor Disorders
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: GINECO-EN102b - BKM120 as Monotherapy in the Treatment of Initial or Recurrent Metastatic Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: DRUG: BKM120
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Achieving Rapid, Safe and Sustained Glucose Control in Adolescents With Suboptimally Controlled Type 1 Diabetes Using Advanced Hybrid Closed Loop Systems
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Tandem Control IQ
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exercise Training as an Intervention to Improve Muscle Function and Recovery Following Bed Rest in Older Adults With Type 2 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes|Muscular Atrophy|Sedentary Behavior|Exercise|Pre-diabetes
Interventions: BEHAVIORAL: Bed Rest Intervention|BEHAVIORAL: Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oxytocin Treatment of Schizophrenia
Status: COMPLETED
Conditions: Paranoia|Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: intranasal spray with oxytocin|OTHER: nasal spray without oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Orally-Administered AMXT 1501 Dicaprate in Normal Healthy Volunteers
Status: WITHDRAWN
Conditions: Neoplasms|Medication Toxicity|Tolerance
Interventions: DRUG: AMXT 1501|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Resveratrol Supplementation in Patients With Mitochondrial Myopathies and Skeletal Muscle Fatty Acid Oxidation Disorders
Status: COMPLETED
Conditions: Mitochondrial Myopathies|Fatty Acid Oxidation Defects
Interventions: DIETARY_SUPPLEMENT: Resveratrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MT2004-30: Tomotherapy for Solid Tumors
Status: TERMINATED
Conditions: Brain and Central Nervous System Tumors|Kidney Cancer|Liver Cancer|Retinoblastoma|Sarcoma
Interventions: BIOLOGICAL: filgrastim|DRUG: busulfan|DRUG: etoposide|DRUG: ifosfamide|DRUG: melphalan|DRUG: thiotepa|PROCEDURE: stem cell transplantation|RADIATION: tomotherapy|RADIATION: total marrow irradiation|DRUG: Mesna|RADIATION: Whole lung radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REperfusion With Cooling in CerebraL Acute IscheMia II
Status: WITHDRAWN
Conditions: Ischemic Stroke|Hypothermia
Interventions: PROCEDURE: Normothermia|PROCEDURE: Mild hypothermia|DEVICE: Trevo Pro Retriever (Stryker Corp.)|DEVICE: Zoll Thermogard XP technology with the Quattro catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mexiletine and Non Dystrophic Myotonias
Status: COMPLETED
Conditions: Non-dystrophic Myotonias|Paramyotonia Congenita|Myotonia Congenita
Interventions: DRUG: Mexiletine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Concentrations of Dextrose Prolotherapy Treatment in Knee Osteoartritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Prolotherapy|OTHER: Home based exercise program|OTHER: Hotpack therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of a 60 Minute Rapid Infusion Rituximab Protocol in Patients With B-cell Malignancies
Status: COMPLETED
Conditions: Indolent or Intermediate Grade B-cell Malignancy
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRIMUS 001: A Study Looking at Two Different Chemotherapy Regimens in Patients With Metastatic Pancreatic Cancer
Status: RECRUITING
Conditions: Neoplasms Pancreatic
Interventions: DRUG: FOLFOX-A|DRUG: Gemcitabe and Abraxane|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of ABBC1 in Volunteers Receiving the Influenza or Covid-19 Vaccine
Status: COMPLETED
Conditions: Immunity|Vaccine Reaction|Influenza|Covid19|Cytokine Storm|Immunologic Deficiency Syndromes
Interventions: DIETARY_SUPPLEMENT: ABBC1 Immunoessential|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Comparison of Mouth Rinse Containing Alcohol-free Chlorhexidine With a Cetylpyridinium Chloride in Periodontal Diseases
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: DRUG: cetylpyridinium chloride mouthwash|DRUG: Chlorhexidine mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Computer-aided Design/Computer-aided Manufacturing for Mild to Moderate Molar Incisor Hypomineralization Treatment
Status: UNKNOWN
Conditions: Molar Incisor Hypomineralization
Interventions: PROCEDURE: Indirect ceramic restoration|PROCEDURE: Direct restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paricalcitol and Gemcitabine in Treating Patients With Advanced Cancer
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: gemcitabine hydrochloride|DRUG: paricalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Formoterol vs Ipatropioum Bromide Plus Fenoterol in Children (5-<12 Years) With Acute Bronchial Obstruction
Status: COMPLETED
Conditions: Acute Bronchial Obstruction, Asthma
Interventions: DRUG: Formoterol fumerate|DRUG: fenoterol/ipratropium bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the GI Sleeve for the Treatment of Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DEVICE: EndoBarrier Gastrointestinal Liner|OTHER: Sham: endoscopy and standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pentostatin, Cyclophosphamide, Rituximab, and Mitoxantrone in Treating Patients With Chronic Lymphocytic Leukemia or Other Low-Grade B-Cell Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim|BIOLOGICAL: rituximab|BIOLOGICAL: sargramostim|DRUG: cyclophosphamide|DRUG: mitoxantrone hydrochloride|DRUG: pentostatin|GENETIC: fluorescence in situ hybridization|GENETIC: gene rearrangement analysis|GENETIC: polymerase chain reaction|GENETIC: protein expression analysis|OTHER: flow cytometry|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sputum-derived Cellular Targets After Xolair (Omalizumab)
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: Omalizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Exercise Effect of EX1 Exercise Program
Status: COMPLETED
Conditions: Aging
Interventions: DEVICE: Wearable Hip Assist Robot(EX1)|BEHAVIORAL: Exercise Program 1|BEHAVIORAL: Exercise Program 2|DEVICE: Without Wearable Hip Assist Robot(EX1)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Treatment of Orthostatic Hypotension
Status: TERMINATED
Conditions: Autonomic Nervous System Diseases|Orthostatic Hypotension|Dopamine Beta-Hydroxylase Deficiency|Orthostatic Intolerance
Interventions: DRUG: Droxidopa Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-caries Potential of a Sodium Monofluorophosphate and Calcium Sodium Phosphosilicate Dentifrice
Status: COMPLETED
Conditions: Caries
Interventions: DRUG: Calcium sodium phosphosilicate|DRUG: Sodium monoflurophosphate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Examine the Efficacy of a Hand Serum and Glove Combination.
Status: COMPLETED
Conditions: Skin Health|Dermatology|Skin Care
Interventions: OTHER: Hand Serum and Glove
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Tacrobell Capsule 1mg to Prograf Capsule 1mg
Status: COMPLETED
Conditions: Immunosuppression
Interventions: DRUG: Tacrobell capsule 1mg|DRUG: Prograf capsule 1mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preemptive Analgesia in Children Using Caudal Epidural Ropivacaine
Status: TERMINATED
Conditions: Inguinal Herniorrhaphy|Orchiopexy
Interventions: DRUG: Ropivacaine|DRUG: Ropivacaine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Subcutaneous Methylnaltrexone For Treatment Of Opioid-Induced Constipation In Patients With Advanced Illness
Status: COMPLETED
Conditions: Opioid-Induced Constipation
Interventions: DRUG: Methylnaltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of High-dose Spironolactone vs. Placebo Therapy in Acute Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Spironolactone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of LJM716 in Squamous Cell Carcinoma of Head and Neck, or HER2+ Breast Cancer or Gastric Cancer
Status: COMPLETED
Conditions: HER2 + Breast Cancer, HER2 + Gastric Cancer, Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma|HER2 + Breast Cancer|HER2 + Gastric Cancer|Squamous Cell Carcinoma of Head and Neck|Esophageal Squamous Cell Carcinoma
Interventions: DRUG: LJM716
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph II of a Novel Anti-angiogenic Agent in Combination With Chemotherapy for the Treatment of Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: CT-322|DRUG: Bevacizumab|DRUG: Bevacizumab placebo (ie saline solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Head-to-head Comparison of [68Ga]Ga-PSMA-D5 With [68Ga]Ga-PSMA-11 PET/CT in PCa Diagnosis, Recurrence, and Metastasis
Status: RECRUITING
Conditions: Prostate Cancer|PET/CT
Interventions: DRUG: [68Ga]Ga-PSMA-D5|DRUG: [68Ga]Ga-PSMA-11
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment With Xeomin Versus Botox in Children With Spastic Equine and Equinovarus Foot Deformation in Pediatric Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Spastic Paraplegia and Hemiparesis|Equine and Equinovarus Foot Deformation
Interventions: DRUG: Xeomin|DRUG: Botox®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mutation of K-RAS, CDKN2A, SMAD4 and TP53 in Pancreatic Cancer: Role of Liquid Biopsy in Preoperative Diagnosis
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DIAGNOSTIC_TEST: Liquid Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Extension Protocol to Evaluate Dose Comparisons of Leucine-Metformin Combinations in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Low Metformin|DRUG: Mid Metformin|DRUG: High Metformin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal GA for Lumbar Spine Surgery
Status: RECRUITING
Conditions: Lumbar Spine Fusion Surgery
Interventions: DRUG: dexmedetomidine, ketamine co-administration with sevoflurane for general anesthesia|DRUG: Conventional general anesthesia by administration of sevoflurane alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BLI850 vs an Active Control Bowel Preparation in Adult Subjects Undergoing Colonoscopy
Status: COMPLETED
Conditions: Colon Cancer
Interventions: DRUG: BLI850|DRUG: polyethylene glycol 3350 based bowel preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin, Paclitaxel, and Carboplatin in Treating Patients With Primary Stage III, Stage IV, or Recurrent Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: DRUG: carboplatin|DRUG: doxorubicin hydrochloride|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Socket Preservation Technique Using Bovine Bone, Platelet Rich Fibrin Or A Combination Of Both: A Clinical, Radiographic And Histological Assesment At 4 Months
Status: ENROLLING_BY_INVITATION
Conditions: Ridge Preservation|Post Extraction Alveolar Bone Resorption
Interventions: PROCEDURE: Socket preservation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Gastric Mucosal Ablation (GMA) of Class III Obesity
Status: RECRUITING
Conditions: Adiposity|Morbid|Obesity
Interventions: DEVICE: Hybrid Argonplasma coagulation (HAPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Paclitaxel With or Without Ramucirumab (LY3009806) in Participants With Gastric or Gastroesophageal Cancer
Status: COMPLETED
Conditions: Gastroesophageal Junction Adenocarcinoma|Gastric Adenocarcinoma
Interventions: DRUG: Ramucirumab|DRUG: Paclitaxel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Kinesio Taping Tension on the Pain Threshold and Tolerance
Status: COMPLETED
Conditions: PRESSURE PAIN THRESHOLD|PAIN TOLERANCE|KINESIOTAPING
Interventions: OTHER: PLACEBO|OTHER: 50% TENSION GROUP|OTHER: 75% TENSION GROUP|OTHER: 100% TENSION GROUP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Jejunal Ketogenesis and Type 2 Diabetes
Status: RECRUITING
Conditions: Obesity, Morbid|Diabetes Mellitus, Type 2|Intestines|Incretins
Interventions: OTHER: Glucemia following Mixed Meal Test|OTHER: Enteroscopy - mucosal ketogenic activity as well as glucose transport
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Blood Salvage in Orthotopic Liver Transplantation With HCC
Status: ENROLLING_BY_INVITATION
Conditions: Hepatocellular Carcinoma|Surgery
Interventions: PROCEDURE: Autotransfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Manual Therapy for Oral Health on Head and Neck Cancer Survivors
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Cancer|Trismus|Dysfunction
Interventions: OTHER: Manual Therapy|OTHER: Control motor exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Of Chitosan in Alveolar Ridge Preservation
Status: ACTIVE_NOT_RECRUITING
Conditions: Tooth Extraction Status Nos|Bone Augmentation
Interventions: PROCEDURE: extraction with chitosan particles as a replacement for bone graft with collagen membrane|PROCEDURE: extraction with placing of allograft particles with collagen membrane|PROCEDURE: tooth extraction only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Refractory Eustachian Tube Dysfunction: Are the Symptoms Related to Endolymphatic Hydrops
Status: WITHDRAWN
Conditions: Eustachian Tube Dysfunction|Endolymphatic Hydrops
Interventions: DRUG: Nasal steroid|PROCEDURE: Myringotomy tube placement|DRUG: Diuretic|DRUG: Antihistamine|BEHAVIORAL: Low salt diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnesium Supplementation for Hypomagnesemia in Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease|Hypomagnesemia
Interventions: DRUG: Mablet 360 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Neuromodulation Technologies in Early Recovery
Status: UNKNOWN
Conditions: Depression|Anxiety|Insomnia
Interventions: DEVICE: Nexalin Brain Stimulator|DEVICE: Fischer Wallace Stimulator|DEVICE: David Delight Stimulator|BEHAVIORAL: Relaxation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monotherapy Versus Placebo Over 7 Days-Non-Nucleoside Reverse Transcriptase Inhibitor-Experienced HIV1 Infected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: GW695634
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: TM vs TSV Implants Loaded Early vs Conventional in Anterior and Posterior Areas
Status: COMPLETED
Conditions: Partial Edentulism|Tooth Disease
Interventions: DEVICE: Trabecular metal dental implants (TM)|DEVICE: Tapered screw-vent implants (TSV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Dynamic Fluctuation of Donor Microbiota Affects the Prognosis of Fecal Microbiota Transplantation for C. Difficile Infection
Status: COMPLETED
Conditions: Clostridium Difficile Infection|Fecal Microbiota Transplantation
Interventions: PROCEDURE: Fecal microbiota transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sympathetic Modulation on Cerebral Vasospasm Secondary to Aneurysmal Subarachnoid Hemorrhage
Status: NOT_YET_RECRUITING
Conditions: Vasospasm, Cerebral|Aneurysmal Subarachnoid Hemorrhage
Interventions: DEVICE: Vectris trial leads and stimulation|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Response of Pathogens to the Respective or Combined Treatment of SRP and Local Minocycline in Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: minocycline|PROCEDURE: surface and root planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iron Absorption and Utilization in Adolescents Infected With Malaria Parasites, Hookworms or Schistosoma
Status: COMPLETED
Conditions: Malaria, Falciparum|Hookworm Infections|Schistosoma Haematobium
Interventions: DIETARY_SUPPLEMENT: Fe-57 orally, Fe-58 intravenously
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combined Pulmonary Rehabilitation and PMR for Long-Term COVID-19 Symptoms: A RCT
Status: RECRUITING
Conditions: Long Covid19|Pulmonary Rehabilitation|Progressive Muscle Relaxation
Interventions: OTHER: Pulmonary rehabilitation protocol|OTHER: Progressive muscle relaxation protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of the AVAPS AE Algorithm in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: COPD|OSA
Interventions: DEVICE: AVAPS-AE|DEVICE: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Open Label Trial of HIV Therapy With d4T (Stavudine), ddI (Didanosine), Nelfinavir and Hydroxyurea in Subjects With Recent HIV Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Hydroxyurea|DRUG: Nelfinavir mesylate|DRUG: Stavudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collective Motivational Interviewing (CMI) for Adolescents With Internet Gaming Disorder
Status: RECRUITING
Conditions: Internet Gaming Disorder
Interventions: BEHAVIORAL: Collective Motivational Interviewing plus Education Materials|OTHER: Control group (Education Materials)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation Intervention for Diabetic Patients
Status: COMPLETED
Conditions: Smoking|Type 2 Diabetes
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy|BEHAVIORAL: Standard smoking cessation intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dural Puncture Epidural Technique Versus Conventional Epidural Techmique
Status: COMPLETED
Conditions: Gynecologic Disease Requiring Laparoscopic Hysterectomy Under Neuraxial Anesthesia
Interventions: PROCEDURE: Conventional Epidural Technique|PROCEDURE: Dural Puncture Epidural Technique using pencil-point 25G Whitacre needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Remimazolam vs Desflurane for General Anesthesia for Ablation of Arrhythmia
Status: COMPLETED
Conditions: Remimazolam|Desflurane|Cryoablation|Arrhythmia|General Anesthesia
Interventions: DRUG: Remimazolam besylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Fermented Milk Containing Lactobacillus Casei Strain Shirota in Sarcopenia Elderly
Status: UNKNOWN
Conditions: Sarcopenia|Inflammation|Aging
Interventions: DIETARY_SUPPLEMENT: Yakult light 300
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Role of Oxytocin in Telling and Detecting Lies
Status: WITHDRAWN
Conditions: Dyssocial Behavior
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial Assessing Efficacy of Various Antimicrobial Techniques for Reducing Bacterial Load
Status: UNKNOWN
Conditions: Disease Due to Gram-positive Bacteria
Interventions: OTHER: Povidone-Iodine|OTHER: Antibiotic topical cream|OTHER: Chlorhexidine 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: IPD in RRMM Characterized With Genomic Abnormalities of Adverse Prognostic
Status: TERMINATED
Conditions: Multiple Myeloma|Relapsed and Refractory Multiple Myeloma|Genetic Condition
Interventions: DRUG: Ixazomib/Pomalidomide/Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Impact of Four Types of Meditation Practices for Relaxation in Cancer Survivors
Status: RECRUITING
Conditions: Hematopoietic and Lymphatic System Neoplasm|Malignant Solid Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Meditation Therapy|PROCEDURE: Meditation Therapy|PROCEDURE: Meditation Therapy|PROCEDURE: Meditation Therapy|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Teens Coping With Parental Military Deployment
Status: TERMINATED
Conditions: Emotional Distress|Behavior Problems
Interventions: BEHAVIORAL: Cognitive Behavioral Group Therapy|BEHAVIORAL: Nondirective supportive group therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bimanual Training in Children With Hemiplegia With Lower Limb and Postural Stimulation (HABIT & Leg)
Status: UNKNOWN
Conditions: Congenital Hemiplegia
Interventions: OTHER: "HABIT-ILE"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Get Going: Accelerometer-Based Intervention to Promote Physical Activity in Frail Older Adults
Status: UNKNOWN
Conditions: Coronary Artery Disease|Heart Failure
Interventions: BEHAVIORAL: Intervention|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bexsero™and Routine Infant Vaccines: Effect of Coadministration on the Safety of Immunization
Status: COMPLETED
Conditions: Meningococcal Infections
Interventions: BIOLOGICAL: 4CMenb|BIOLOGICAL: diphtheria,tetanus,pertussis+polio+Hepatitis B+HiB|BIOLOGICAL: conjugated pneumococcal vaccine|BIOLOGICAL: MMRV
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neoadjuvant Doxorubicin/Cyclophosphamide Followed by Docetaxel (AC-Doc) Versus Dose-Dense Doxorubicin and Docetaxel (ADoc) in Breast Cancer
Status: COMPLETED
Conditions: Primary Breast Cancer
Interventions: DRUG: Adriamycin (Doxorubicin), Docetaxel, Tamoxifen|DRUG: Adriamycin (Doxorubicin), Docetaxel, Tamoxifen, Cyclophosphamid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Pedicle Osteotomy for Stenosis Trial
Status: SUSPENDED
Conditions: Lumbar Spinal Stenosis|Spondylolisthesis, Grade 1|Neurogenic Claudication
Interventions: DEVICE: Pedicle Lengthening Osteotomy with Altum® Device|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Daily Undulating Periodization Methods With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Weight-Lifting Exercise Program
Interventions: OTHER: Periodized training with motor practice|OTHER: Simple Periodized Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate a Potassium Normalization Treatment Regimen Including Sodium Zirconium Cyclosilicate (ZS) Among Patients With S-K ≥5.8
Status: COMPLETED
Conditions: Hyperkalemia
Interventions: DRUG: Placebo|DRUG: Sodium Zirconium Cyclosilicate(ZS)|DRUG: Insulin|DRUG: Glucose|DRUG: Insulin|DRUG: Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Differentiating the Effects of Substance P and Beta-endorphin
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Aprepitant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Dexmedetomidine on Improving Intubating Conditions Without the Use of Muscle Relaxant
Status: COMPLETED
Conditions: Intubation|Muscle Relaxation|Dexmedetomidine
Interventions: DRUG: Precedex 200 MCG in 2 ML Injection|OTHER: C group:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Ex-vivo Modulatory Effect of Biological Drugs for Inflammatory Bowel Disease on the Mucosa and on Peripheral Blood Mononuclear Cells
Status: COMPLETED
Conditions: Inflammatory Bowel Disease
Interventions: BIOLOGICAL: Ex-vivo stimulation of cells with infliximab, golimumab, adalimumab, vedolizumab and ustekinumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Edaravone Dexborneol for Treatment of Hypertensive Intracerebral Hemorrhage
Status: UNKNOWN
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: Edaravone Dexborneol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Earplugs on Temporomandibular Joint
Status: COMPLETED
Conditions: Ear Protective Devices|Temporomandibular Joint Disorders|Physical Therapy Modalities
Interventions: DEVICE: Earplug|DEVICE: occlusal splint|OTHER: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Ventilatory Weaning Guided by a New Index
Status: COMPLETED
Conditions: Respiration, Artificial
Interventions: DEVICE: Timed Inspiratory Effort (TIE index)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) in People With Post Covid-19 Condition.
Status: RECRUITING
Conditions: Emotional Disorder|Post COVID-19 Condition|Anxiety Disorders|Depressive Disorder
Interventions: BEHAVIORAL: Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Chronic Renal Insufficiency
Status: COMPLETED
Conditions: Vitamin D Deficiency|Chronic Renal Insufficiency
Interventions: DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Alcon® Ex-PRESS® Glaucoma Filtration Device in Japanese Patients
Status: COMPLETED
Conditions: Glaucoma
Interventions: DEVICE: Ex-PRESS® Glaucoma Filtration Device, Model P50PL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BCMA-Specific CAR T-Cells Combined With a Gamma Secretase Inhibitor (JSMD194) to Treat Relapsed or Persistent Multiple Myeloma
Status: TERMINATED
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: BIOLOGICAL: BCMA-specific CAR-expressing T Lymphocytes|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Gamma-Secretase Inhibitor LY3039478|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacokinetic Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of "Allergovac Poliplus" in Polysensitized Patients With Allergic Rhinitis/Rhinoconjunctivitis, With or Without Asthma
Status: COMPLETED
Conditions: Rhinitis, Allergic|Rhinoconjunctivitis
Interventions: BIOLOGICAL: Allergen Immunotherapy (AIT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sleep and Pain Interventions in Fibromyalgia
Status: COMPLETED
Conditions: Insomnia|Fibromyalgia
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia (CBT-I)|BEHAVIORAL: Cognitive Behavioral Therapy for Pain (CBT-P)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Portal Flu Vaccine Reminders_RCT 5 (LADHS)
Status: COMPLETED
Conditions: Influenza|Respiratory Tract Infections
Interventions: BEHAVIORAL: Enhanced texts with Callback by a Person|BEHAVIORAL: Enhanced Bidirectional Texts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Graded Motor Imagery in Elbow Limitation
Status: COMPLETED
Conditions: Elbow Fracture|Limitation, Mobility|Pain, Postoperative|Upper Extremity Problem
Interventions: OTHER: Graded Motor Imagery|OTHER: Standard Rehabilitation|OTHER: Home Exercise Program|OTHER: Cold Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab With or Without Docetaxel in Treating Patients With Previously Treated Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: rhuMAB-VEGF|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suberoylanilide Hydroxamic Acid, Fluorouracil, Leucovorin, and Oxaliplatin in Treating Patients With Progressive Metastatic or Unresectable Colorectal Cancer or Other Solid Tumors
Status: COMPLETED
Conditions: Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage III Colon Cancer|Stage III Rectal Cancer|Stage IV Colon Cancer|Stage IV Rectal Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: oxaliplatin|DRUG: leucovorin calcium|DRUG: vorinostat|DRUG: fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Swaddling Method on Stress Level in Newborns Administration to Nasal CPAP
Status: COMPLETED
Conditions: Nursing Caries|Newborn Illness|Nurse's Role
Interventions: OTHER: nonpharmacologic intervention (swaddling)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Postprandial Glucodynamic Response to Insulin Glargine/Lixisenatide Fixed Ratio Combination in Japanese Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin glargine/ lixisenatide fixed-ratio combination HOE901/AVE0010|DRUG: Insulin glargine HOE901|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Penicillin Allergy Risk-Stratification and Delabeling of Low-Risk Patients
Status: WITHDRAWN
Conditions: Antibiotic Allergy
Interventions: OTHER: Physician-targeted CDS tool for PCN allergy delabeling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Cranberry and Agaves Extract on Microbiota and Intestinal Health
Status: COMPLETED
Conditions: Endotoxemia|Metabolic Syndrome|Glucose Metabolism Disorders|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Cranberry|DIETARY_SUPPLEMENT: Agaves|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Olmutinib Trial in T790M (+) NSCLC Patients Detected by Liquid Biopsy Using BALF Extracellular Vesicular DNA
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Olmutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Carbon Dioxide Pressure (tcPCO2) Monitoring for the Prediction of Extubation Failure in the ICU
Status: COMPLETED
Conditions: Ventilator Weaning
Interventions: PROCEDURE: tcPCO2 measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Hospice Advanced Dementia Symptom Management and Quality of Life Trial (HAS-QOL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Dementia
Interventions: BEHAVIORAL: Aliviado Dementia Care-Hospice Edition QAPI program|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Seaweed Iodine Delivered Via Food or Supplementation
Status: COMPLETED
Conditions: Iodine Deficiency
Interventions: DIETARY_SUPPLEMENT: Reformulated pizza|DIETARY_SUPPLEMENT: Control pizza|DIETARY_SUPPLEMENT: Seaweed capsule|DIETARY_SUPPLEMENT: Control capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Percutaneous Minimal Invasive Pedicular Screw and Rod Insertion in Circumferential Lumbar Fusion
Status: COMPLETED
Conditions: Degenerative Disc Disease
Interventions: OTHER: Pedicle screws|OTHER: Percutaneous stab incisions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Safety and Effectiveness of GP0112 for Cheek Augmentation and Correction of Midface Contour Deficiencies
Status: COMPLETED
Conditions: Cheek Wrinkles|Midface Contour Deficiencies
Interventions: DEVICE: GP0112|DEVICE: Restylane Lyft Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre- vs. Postoperative Thromboprophylaxis in Pancreatic Surgery
Status: RECRUITING
Conditions: Pancreas Cancer|Pancreas Neoplasm|Surgery|Thrombosis|Bleeding
Interventions: DRUG: enoxaparin/tinzaparin/dalteparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Utero-placental Vascularisation in Normal and Preeclamptic and Intra-uterine Growth Restriction Pregnancies
Status: UNKNOWN
Conditions: Preeclampsia|Intra-uterine Growth Restriction
Interventions: DEVICE: Doppler
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Arabinoxylan Oligosaccharides Consumption on Insulin Resistance in Patients With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Arabinoxylan oligosaccharides|DIETARY_SUPPLEMENT: Short chain fatty acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Trial Investigating the Effect of Salmon Bone Meal on Bone Mass Among Osteopenic Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteopenia|Osteopenia of the Elderly
Interventions: DIETARY_SUPPLEMENT: CalGo|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION