pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Magnesium Supplementation on Polycystic Ovary Syndrome
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: DIETARY_SUPPLEMENT: Magnesium Oxide|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Feeding in Infants With Pierre Robin Syndrome
Status: RECRUITING
Conditions: Pierre Robin Syndrome
Interventions: BEHAVIORAL: systematic therapy|DEVICE: intermittent oro-esophageal tube feeding|DEVICE: gastric tube feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety and Tolerability of GS1-144 in Healthy Volunteers
Status: RECRUITING
Conditions: Vasomotor Symptoms|Adult Healthy Volunteers
Interventions: DRUG: GS1-144|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study of Atezolizumab and Trastuzumab in Combination With Capecitabine and Oxaliplatin in Patients With HER2 Positive Locally Advanced Resectable Gastric Cancer of Adenocarcinoma of Gastroesophageal Junction
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Atezolizumab|DRUG: Trastuzumab|DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: suPAR to Guide Antibiotics in Emergency Department
Status: UNKNOWN
Conditions: Sepsis
Interventions: DRUG: Meropenem|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Keratoconus With Advanced Corneal Crosslinking
Status: COMPLETED
Conditions: Keratoconus
Interventions: PROCEDURE: Corneal reshaping/crosslinking (CRXL)|PROCEDURE: Corneal Crosslinking (CXL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Long-term Effect on Oral Health Using a Powered Toothbrush in Individuals With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Oral Health|Quality of Life
Interventions: DEVICE: Powered toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hemodynamic Monitoring and Correlation Between Electrical Cardiometry and Esophageal Doppler in Patients Undergoing Major Abdominal Surgery
Status: COMPLETED
Conditions: Electrical Cardiometry VS Esophageal Doppler
Interventions: DIAGNOSTIC_TEST: Esophageal doppler
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial of Omalizumab in Participants With Chronic Rhinosinusitis With Nasal Polyps
Status: COMPLETED
Conditions: Nasal Polyps|Chronic Rhinosinusitis
Interventions: DRUG: Omalizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robotized Navigation Compared to Conventional Technique in Total Knee Replacement
Status: ACTIVE_NOT_RECRUITING
Conditions: Arthritis, Degenerative|Osteo Arthritis Knee
Interventions: PROCEDURE: Navio|PROCEDURE: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of Diet-microbiota Interactions in Irritable Bowel Syndrome
Status: RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: L-Histidine|DIETARY_SUPPLEMENT: High-FODMAP beverage|DIETARY_SUPPLEMENT: Low-FODMAP beverage|DIETARY_SUPPLEMENT: Lactobacillus acidophilus CL1285, L. casei LBC80R and L. rhamnosus CLR2.|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Efficacy and Safety of Sitagliptin and MK0431A in Comparison to a Commonly Used Medication in Patients With Type 2 Diabetes (0431-068)(COMPLETED)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Comparator: sitagliptin phosphate (sitagliptin)|DRUG: sitagliptin phosphate (+) metformin hydrochloride|DRUG: Comparator: pioglitazone|DRUG: Matching placebo to pioglitazone|DRUG: Matching placebo to sitagliptin|DRUG: Matching Placebo to Sita/Met FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Perioperative Use of Breztri Aerosphere to Relieve Cough After Lobectomy
Status: UNKNOWN
Conditions: Lung Cancer, Nonsmall Cell|Perioperative|Cough|Drug Effect|Drug Toxicity
Interventions: DRUG: Breztri Aerosphere|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Oxygen Delivery Devices for Reversal of Altitude-Induced Hypoxemia in Normal Subjects
Status: COMPLETED
Conditions: Hypoxemia|Hypobaric Hypoxemia
Interventions: DEVICE: Pulse-dose oxygen|DEVICE: Cylinder oxygen delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Health for Hearts United Collaborative
Status: ENROLLING_BY_INVITATION
Conditions: Cardiovascular Disease Risk Reduction
Interventions: BEHAVIORAL: Health for Hearts United Planning for Health|BEHAVIORAL: Health for Hearts United Preparing for Health|BEHAVIORAL: Health for Hearts United Delivery of Health|OTHER: Health for Hearts United Comparison Group Health Ministry Development
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Colesevelam as Add-on to Pioglitazone Therapy for Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Colesevelam|DRUG: Placebo|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Snooze Control: Sleep Duration & Glucose Metabolism
Status: COMPLETED
Conditions: Glucose Metabolism Disorders
Interventions: BEHAVIORAL: OGTT after deprived sleep first|BEHAVIORAL: OGTT after sufficient sleep first
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase I Clinical Trial to Investigate the Safety, Tolerability, and Pharmacokinetic Characteristics of TT-01025-CL in Healthy Subjects
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: TT-01025-CL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment With a Scheme With Low Doses of Bortezomib / Melphalan / Prednisone (MPV) in Patients With Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib|DRUG: Melphalan|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transdisciplinary Studies of CBT for Anxiety in Youth: Child Anxiety Treatment Study
Status: COMPLETED
Conditions: Generalized Anxiety Disorder|Separation Anxiety Disorder|Social Phobia
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Client Centered Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of KOVIR Capsule in the Combination Regimen With Background Treatment in COVID-19 Patients
Status: UNKNOWN
Conditions: COVID-19
Interventions: DIETARY_SUPPLEMENT: KOVIR capsule combined with background treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomised, Controlled Study to Assess Safety and Tolerance of Infant Formula With Prebiotics and Postbiotics in Healthy Infants.
Status: COMPLETED
Conditions: Healthy Term Infants
Interventions: OTHER: milk based infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Does Neurostimulation Improve Efficacy for Ultrasound-Guided Transperineal Pudendal Nerve Block In Children
Status: UNKNOWN
Conditions: Phimosis
Interventions: PROCEDURE: Pudendal nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serial FLT PET Imaging in Cancer Patients for Monitoring of Response to Therapy
Status: WITHDRAWN
Conditions: Histologically-confirmed Malignancies
Interventions: RADIATION: [18F] FLT|DEVICE: PET/CT scans
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Non Pharmacological Treatment in Alzheimer's Disease and Associated Disorders
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: OTHER: Bras A (EHPAD Training and stimulation)|OTHER: EHPAD Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Kinesio Taping Application for Dysmenorrhea
Status: UNKNOWN
Conditions: Dysmenorrhea
Interventions: OTHER: Kinesio taping|DRUG: NSAID's
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight
Status: RECRUITING
Conditions: 16P11.2 Deletion Syndrome|16p11.2 Duplications|1Q21.1 Deletion|1Q21.1 Microduplication Syndrome (Disorder)|ACTL6B|ADNP|AHDC1|ANK2|ANKRD11|ARID1B|ASH1L|BCL11A|CHAMP1|CHD2|CHD8|CSNK2A1|CTBP1|CTNNB1 Gene Mutation|CUL3|DDX3X|DNMT3A|DSCAM|DYRK1A|FOXP1|GRIN2A|GRIN2B|HIVEP2-Related Intellectual Disability|HNRNPH2|KATNAL2|KDM5B|KDM6B|KMT2C Gene Mutation|KMT2E|KMT5B|MBD5|MED13L|PACS1|PPP2R5D-Related Intellectual Disability|PTCHD1|REST|SCN2A Encephalopathy|SETBP1 Gene Mutation|SETD5|SMARCA4 Gene Mutation|SMARCC2|STXBP1 Encephalopathy With Epilepsy|SYNGAP1-Related Intellectual Disability|TBR1|ARHGEF9|HNRNPU|PPP3CA|PPP2R1A|SLC6A1|2p16.3 Deletions|5q35 Deletions|5q35 Duplications|7q11.23 Duplications|15Q13.3 Deletion Syndrome|16p11.2 Triplications|16P12.2 Microdeletion|16P13.11 Microdeletion Syndrome (Disorder)|17Q12 Microdeletion Syndrome (Disorder)|17Q12 Duplication Syndrome|17Q21.31 Deletion Syndrome|17q21.3 Duplications|ACTB|ADSL|AFF2|ALDH5A1|ANK3|ARX|ATRX Gene Mutation|AUTS2 Syndrome|BCKDK|BRSK2|CACNA1C|CAPRIN1|CASK|CASZ1|CHD3|CIC|CNOT3|CREBBP Gene Mutation|CSDE1|CTCF|DEAF1|DHCR7|DLG4|EBF3|EHMT1|EP300 Gene Mutation|GIGYF1|GRIN1|GRIN2D|IQSEC2-Related Syndromic Intellectual Disability|IRF2BPL|KANSL1|KCNB1|KDM3B|NEXMIF|KMT2A|MBOAT7|MEIS2|MYT1L|NAA15|NBEA|NCKAP1|NIPBL|NLGN2|NLGN3|NLGN4X|NR4A2|NRXN1|NRXN2|NSD1 Gene Mutation|PHF21A|PHF3|PHIP|POMGNT1|PSMD12|RELN|RERE|RFX3|RIMS1|RORB|SCN1A|SETD2 Gene Mutation|SHANK2|SIN3A|SLC9A6|SON|SOX5|SPAST|SRCAP|TAOK1|TANC2|TCF20|TLK2|TRIO|TRIP12|UPF3B|USP9X|VPS13B|WAC|WDFY3|ZBTB20|ZNF292|ZNF462|2Q37 Deletion Syndrome|9q34 Duplications|15q15 Deletions|15Q24 Deletion|NR3C2|SYNCRIP|2q34 Duplication|2q37.3 Deletion|6q16 Deletion|15q11.2 BP1-BP2 Deletion|16p13.3 Deletion|17Q11.2 Microduplication Syndrome (Disorder)|17p13.3|Xq28 Duplication|CLCN4|CSNK2B|DYNC1H1|EIF3F|GNB1|MED13|MEF2C|RALGAPB|SCN1B|YY1|Xp11.22 Duplication|PACS2|MAOA|MAOB|HNRNPC|HNRNPD|HNRNPK|HNRNPR|HNRNPUL2|5P Deletion Syndrome|TCF7L2 Gene Mutation|HECW2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Testing a Community-Friendly Risk Reduction Intervention for Injection Drug Users
Status: COMPLETED
Conditions: HIV|Opioid Dependence
Interventions: BEHAVIORAL: Community-friendly Health Recovery Program|BEHAVIORAL: Time-and-Attention-Matched Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Placebo Study to Assess the Inhalation Profile in Asthmatic Patients Using the Nexthaler® Dry Powder Inhaler (DPI) Device
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: Inhalation through Chiesi NEXThaler DPI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Transcranial Direct Current Stimulation as an Augmenting Intervention for Major Depression
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DEVICE: Transcranial Direct Current Stimulation|DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Romosozumab Versus Denosumab in GIOP: a 2-year Extension Study
Status: NOT_YET_RECRUITING
Conditions: Osteoporosis|Glucocorticoids Toxicity
Interventions: DRUG: Romosozumab|DRUG: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant TRastuzumab Deruxtecan for HER2-positive Gastroesophageal Cancer With Persistence of miNImal Residual Disease
Status: RECRUITING
Conditions: Gastric Cancer|HER2-positive Gastric Cancer
Interventions: DRUG: Experimental|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The RODEO Micro Mapping Catheter in Cryoablation Procedures
Status: UNKNOWN
Conditions: Atrial Fibrillation|Paroxysmal Atrial Fibrillation|Persistent Atrial Fibrillation|Arrhythmias, Cardiac|Cardiovascular Diseases|Heart Diseases
Interventions: DEVICE: Rodeo Micro Mapping Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utility of Amantadine Hydrochloride in the Treatment of Post-traumatic Irritability
Status: COMPLETED
Conditions: Irritable Mood|Aggression|Traumatic Brain Injury
Interventions: DRUG: Amantadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Insulin Detemir in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin detemir|DRUG: insulin NPH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Abuse Potential of Oxymorphone Compared to Other Mu Opioid Agonists.
Status: COMPLETED
Conditions: Opioid Use Disorder
Interventions: DRUG: Intravenous Challenge Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diaphragm Function After Reversal of Rocuronium-induced Neuromuscular Blockade With Sugammadex or Neostigmine in Children
Status: RECRUITING
Conditions: Neuromuscular Block, Residual
Interventions: DRUG: Sugammadex|DRUG: Neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Demonstrate the Efficacy (Including Inhibition of Structural Damage), Safety and Tolerability up to 2 Years of Secukinumab in Active Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: BIOLOGICAL: Secukinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Tolerability of Abrocitinib in Subjects With Moderate to Severe Chronic Hand Eczema Refractory to Corticosteroid Therapy
Status: NOT_YET_RECRUITING
Conditions: Chronic Hand Eczema
Interventions: DRUG: Abrocitinib 200 mg|DRUG: Abrocitinib 100 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Relapse Rates Between Standard Ureteroscopic Removal Of Ureteral Stone And Standard Removal With Additional Ureterorenic Clearing Of Non-Symptomatic Stones In The Kidney
Status: COMPLETED
Conditions: Ureteral Stones, Kidney Stones
Interventions: PROCEDURE: Symptomatic stone removal|PROCEDURE: Asymptomatic kidney stones and ureteral stone removed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Techniques for Breast Cancer-Related Lymphedema.
Status: COMPLETED
Conditions: Breast Cancer Lymphedema
Interventions: OTHER: Complex Physical Therapy plus Pressotherapy|OTHER: Kinesio Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Calcineurin Inhibitor-Free Interventions BMT CTN 1301 for Prevention of Graft-versus-Host Disease (BMT CTN 1301)
Status: COMPLETED
Conditions: Acute Leukemia|Myelodysplasia
Interventions: PROCEDURE: Unmanipulated Bone Marrow Graft with Tacrolimus/Methotrexate|PROCEDURE: Mobilized CD34-selected Peripheral Blood Stem Cell graft|PROCEDURE: Unmanipulated Bone Marrow Graft with Cyclophosphamide|DRUG: Cyclophosphamide|DRUG: Tacrolimus|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intermittent Preventive Treatment With Azithromycin-containing Regimens in Pregnant Women in Papua New Guinea
Status: COMPLETED
Conditions: Malaria in Pregnancy|Sexually Transmitted Infections|Anaemia
Interventions: DRUG: chloroquine, sulphadoxine pyrimethamine, LLIN|DRUG: azithromycin, sulphadoxine pyrimethamine, LLIN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Testing the Addition of an Anti-cancer Drug, Navtemadlin, to the Usual Treatments (Cytarabine and Idarubicin) in Patients With Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
Interventions: DRUG: Cytarabine|DRUG: Idarubicin Hydrochloride|DRUG: Navtemadlin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Intra-articular Dexamethasone and Dexamethasone Added to Bupivacaine in Interscalene Brachial Plexus
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: intraarticular dexamethasone|PROCEDURE: interscalene dexamethasone|PROCEDURE: serum phsyologic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Once Daily Versus Conventional Dosing of Asacol in the Maintenance of Quiescent Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Asacol (mesalamine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: The Effect of the GLP-1 Receptor Agonists on Blood Levels of Lipoprotein (a)
Status: UNKNOWN
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Liraglutide|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence Rates of USI, BO, DO and Their Clinical and Urodynamic Findings in Women With ≥Stage II Cystocele
Status: COMPLETED
Conditions: Lower Urinary Tract Symptom in Severe Cystocele Women
Interventions: DIAGNOSTIC_TEST: Pad test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anti-CEA CAR-T Cells to Treat Colorectal Liver Metastases
Status: RECRUITING
Conditions: Colorectal Cancer|Metastatic Liver Cancer
Interventions: DRUG: Anti-CEA CAR-T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Triclosan Coated Suture in Obstetrical Surgery
Status: COMPLETED
Conditions: Cesarean Section; Infection
Interventions: DRUG: Coated Vicryl+|DRUG: Vicryl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Controlled Trial to Test the Effect of a Smartphone Quit Smoking Intervention on Young Adult Smokers
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: BEHAVIORAL: Crush the Crave Application|BEHAVIORAL: On the Road to Quitting - Self Help
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: methotrexate|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Gastric Bypass for Type 2 Diabetes Mellitus With Body Mass Index (BMI) < 35
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: PROCEDURE: Gastric bypass for diabetic patients <35 BMI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Anlotinib in Patients With Medullary Thyroid Carcinoma(ALTER01031)
Status: COMPLETED
Conditions: Medullary Thyroid Carcinoma
Interventions: DRUG: Anlotinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Feedback Reports to Improve Acute Coronary Syndromes (ACS) Care
Status: COMPLETED
Conditions: Acute Coronary Syndromes
Interventions: BEHAVIORAL: Targeted Feedback Reports|BEHAVIORAL: Targeted Feedback Report
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Extended Release Tacrolimus vs. Twice-Daily Tacrolimus
Status: COMPLETED
Conditions: End Stage Renal Disease|Rejection of Renal Transplant
Interventions: DRUG: Tacrolimus|DRUG: Tacrolimus Extended Release Oral Tablet [Envarsus]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy and Topical Antifungal for Onychomycosis in Patients With Diabetes.
Status: ACTIVE_NOT_RECRUITING
Conditions: Dermatologic Disease|Onychomycosis of Toenail|Diabetic Foot|Diabetes Mellitus
Interventions: COMBINATION_PRODUCT: Photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalised Therapy for Metastatic ADPC Determined by Genetic Testing and Avatar Model Generation
Status: UNKNOWN
Conditions: Adenocarcinoma
Interventions: DRUG: Personalised treatment|DRUG: Treatment chosen per investigator´s judge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dabigatran Versus Conventional Treatment for Prevention of Silent Cerebral Infarct in Atrial Fibrillation Associated With Valvular Disease
Status: COMPLETED
Conditions: Atrial Fibrillation|Valve Heart Disease
Interventions: DRUG: Dabigatran|DRUG: Acetylsalicylic acid|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Bioavailability, Pharmacodynamics and Safety of SHR-1209 Administered by Single Subcutaneous Injection at Different Sites in Healthy Volunteers
Status: COMPLETED
Conditions: Hypercholesterolemia and Hyperlipidemia
Interventions: DRUG: SHR-1209
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of Cannabis for Essential Tremor
Status: COMPLETED
Conditions: Essential Tremor
Interventions: DRUG: CBD/THC|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Immunogenicity of ACI-24 Vaccine in Adults With Down Syndrome
Status: COMPLETED
Conditions: Down Syndrome
Interventions: BIOLOGICAL: ACI-24 low dose|BIOLOGICAL: ACI-24 high dose|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cabozantinib as a Targeted Strategy to Reverse Carfilzomib Resistance in Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma|Refractory Multiple Myeloma|Relapsed/Refractory Multiple Myeloma
Interventions: DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triple-branch Stent Graft Placement and Total-arch Replacement for the Treatment of Acute DeBakey I Aortic Dissection
Status: UNKNOWN
Conditions: Acute Aortic Dissection
Interventions: PROCEDURE: triple-branched stent graft|PROCEDURE: four-branched Dacron graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide
Status: RECRUITING
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: DRUG: Talquetamab|DRUG: Pomalidomide|DRUG: Teclistamab|DRUG: Elotuzumab|DRUG: Dexamethasone|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of Valproate as Adjunctive Treatment for Toxoplasma Gondii Infection in Early Course Schizophrenia
Status: COMPLETED
Conditions: Toxoplasmosis|Schizophrenia
Interventions: DRUG: Sodium Valproate treatment|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Haploidentical Hematopoietic Stem Cell Transplantation Using CAMPATH-1H
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute|Leukemia, Lymphoblastic, Acute
Interventions: PROCEDURE: Haploidentical hematopoietic stem cell transplantation|DRUG: Busulfan|DRUG: Cyclophosphamide|DRUG: CAMPATH-1H|DRUG: Cyclosporin A|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Music Listening to Shortening Time for Biophysical Profile
Status: COMPLETED
Conditions: Fetal Status, Nonreassuring
Interventions: DIAGNOSTIC_TEST: Trans abdominal ultrasound for assess biophysical profile
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Two Methods of Negative Pressure Wound Therapy
Status: COMPLETED
Conditions: Acute Wounds From Trauma|Dehiscence or Surgical Complications
Interventions: DEVICE: Gauze suction (G-SUC)|DEVICE: Vacuum Assisted Closure Device (VAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TransGrade Multimodal Neuromodulation of the Dorsal Root Ganglion Ensemble for Refractory Neuropathic Pain
Status: TERMINATED
Conditions: Neuropathic Pain|Pain, Chronic
Interventions: DEVICE: Dorsal Root Ganglion Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vibrating, Cold Device for Pediatric Intravenous (IV) Cannulation Pain Relief
Status: COMPLETED
Conditions: Pain|Anxiety
Interventions: DEVICE: Buzzy|DRUG: Topical Lidocaine 4% Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of 360° Virtual Reality Movies on Fear and Anxiety
Status: RECRUITING
Conditions: Fear|Anxiety|Breast Cancer|Lung Cancer|Prostate Cancer|Head and Neck Cancer|Brain Tumor
Interventions: OTHER: Questionnaire: SPIRIT|OTHER: Questionnaire: HADS|OTHER: Questionnaire: QSC-R23|OTHER: General questions|OTHER: Clinical data collected
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of 0417 Ointment in the Treatment of Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: 0417|DRUG: Vehicle of 0417 test product|DRUG: Tacrolimus Ointment 0.03%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ex Vivo Gene Therapy Clinical Trial for RDEB Using Genetically Corrected Autologous Skin Equivalent Grafts
Status: ACTIVE_NOT_RECRUITING
Conditions: Epidermolysis Bullosa Dystrophica, Recessive
Interventions: BIOLOGICAL: COL7A1-SIN retroviral vector engineered autologous tissue-engineered skin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Watchful Waiting Versus Open Tension-free Repair of Inguinal Hernia in Asymptomatic or Minimally Symptomatic Men
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: PROCEDURE: watchful waiting or tension-free hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study Evaluating The Benefit of Adding Rucaparib to Enzalutamide for Men With Metastatic Prostate Cancer That Has Become Resistant To Testosterone-Deprivation Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Prostate Adenocarcinoma|Stage IV Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: DRUG: Enzalutamide|DRUG: Rucaparib camsylate|DRUG: Placebo|DRUG: Leuprolide Acetate|DRUG: Goserelin Acetate|DRUG: Degarelix|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of PSMA-targeted 18F-DCFPyL PET/CT for the Detection of Clinically Significant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: 18F-DCFPyL Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Culturally Informed Family Based Treatment of Adolescents: A Randomized Trial
Status: COMPLETED
Conditions: Substance Use Disorders|Risk Behavior|Psychiatric Disorders|Family Dysfunction
Interventions: BEHAVIORAL: Family Therapy based on Structural Family Therapy|BEHAVIORAL: Group Therapy|BEHAVIORAL: Psychoeducational Sessions|BEHAVIORAL: Individual Adolescent Therapy Sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Vaccine Acceptance Through EHR Integrated Patient- and Provider-Facing Decision Support
Status: NOT_YET_RECRUITING
Conditions: Vaccine Hesitancy|Vaccine Refusal
Interventions: OTHER: LetsTalkShots (patient-facing CDS)|OTHER: LetsTalkShots (provider-facing CDS)|OTHER: Appointment Reminder Message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vasomotor Reactivity In Cerebral Small Vessel Disease And New Approach To Treat Lacunar Stroke
Status: COMPLETED
Conditions: Cerebrovascular Accident|Hypercholesterolemia
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Allogenic Mesenchymal Stem Cells for Patients With Chronic Graft Versus Host Disease
Status: UNKNOWN
Conditions: Chronic Graft Versus Host Disease
Interventions: BIOLOGICAL: Biological: mesenchymal stem cell|DRUG: Cyclosporine and Glucocorticoid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of CMNa Combined With Preoperatie Concurrent Chemoradiotherapy for Locally Advanced ESCC
Status: TERMINATED
Conditions: Esophageal Neoplasms
Interventions: DRUG: Sodium Glycididazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Glycemic Control and Skeletal Health Study
Status: COMPLETED
Conditions: Atherosclerosis|Cardiovascular Diseases|Hypercholesterolemia|Hypertension|Diabetes Mellitus|Coronary Disease
Interventions: DRUG: hypoglycemic agents, hydroxymethylglutaryl-CoA Reductase inhibitors, hypertensive agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Window of Opportunity Phase I Study of UGN-201 in Patients With Bladder Cancer Undergoing Radical Cystectomy Protocol #: 2021-0630
Status: SUSPENDED
Conditions: Bladder Cancer|Bladder
Interventions: DRUG: UGN-201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Trial of Intrasite Vancomycin Pharmacokinetics
Status: TERMINATED
Conditions: Surgical Site Infection
Interventions: DRUG: Intrasite Vancomycin|DRUG: IV Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Clinical Application of Near-infrared Whole Body Heat Shock Multimodal Technique in Treatment of Castration-resistant Prostate Cancer
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer (CRPC)
Interventions: DRUG: Immunotherapy|DRUG: Targeted therapy|DEVICE: Hyperthermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Technology Assisted Physical Activity Among Hospitalised Patients With Respiratory Disease
Status: COMPLETED
Conditions: Respiratory Disease
Interventions: DEVICE: Visual feedback of physical activity|DEVICE: No feedback of physical activity|DEVICE: Measurement of physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose Ranging Study of BMS-945429 in Subjects With Moderate to Severe Crohn's Disease
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: Placebo matching with BMS-945429|BIOLOGICAL: Placebo matching with BMS-945429|BIOLOGICAL: Placebo matching with BMS-945429|BIOLOGICAL: Placebo matching with BMS-945429|BIOLOGICAL: BMS-945429|BIOLOGICAL: BMS-945429|BIOLOGICAL: BMS-945429|BIOLOGICAL: BMS-945429|BIOLOGICAL: BMS-945429|BIOLOGICAL: BMS-945429|BIOLOGICAL: BMS-945429|BIOLOGICAL: BMS-945429|BIOLOGICAL: BMS-945429
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First Line Pembrolizumab, Plinabulin Plus Etoposide and Platinum (EP) for ES-SCLC
Status: NOT_YET_RECRUITING
Conditions: Small Cell Lung Cancer Extensive Stage
Interventions: DRUG: Pembrolizumab, Plinabulin plus Etoposide and Platinum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reactivating Specific Memories During Sleep in Conjunction With a Suppression Context
Status: RECRUITING
Conditions: Sleep|Consolidation
Interventions: BEHAVIORAL: Targeted memory reactivation (odors)|BEHAVIORAL: Targeted memory reactivation (sounds)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of 60-days Saccharomyces Boulardii and Superoxide Dismutase Supplementation in Obese Adults
Status: COMPLETED
Conditions: Obesity|Superoxide Dismutase
Interventions: DIETARY_SUPPLEMENT: Saccharomyces boulardii and SOD|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Spa Medicine on the Example of Comprehensive Therapy in the Spa Resort Przerzeczyn Zdroj
Status: COMPLETED
Conditions: Osteoarthritis|Degenerative Disc Disease
Interventions: PROCEDURE: Redon-sulfide baths|PROCEDURE: Partial Mud Baths|PROCEDURE: Kinesiotherapy|PROCEDURE: Terrain Therapy|PROCEDURE: Dry Massage|PROCEDURE: Laser Therapy|PROCEDURE: Low-frequency Magnetic Field|PROCEDURE: Ultrasonotherapy|PROCEDURE: Cryotherapy|PROCEDURE: Electrotherapy|PROCEDURE: Light Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Compare Post Prandial Blood Glucose Control of BioChaperone® Combo With Humalog® Mix25 and With Simultaneous Injections of Humalog® and Lantus® in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: BioChaperone® Combo|DRUG: Humalog® Mix25|DRUG: Humalog®|DRUG: Lantus®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventative Intervention for Cholera for 7 Days
Status: RECRUITING
Conditions: Cholera|Water-Related Diseases|Diarrhea Infectious
Interventions: BEHAVIORAL: PICHA7 mHealth program|OTHER: Standard Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Phase IIb, Multi-Center, Multinational, Double-Blind, Placebo-Controlled Study, With an Open Label Extension, to Evaluate Safety, Tolerability and Efficacy of PrimeC in Subjects With ALS
Status: ACTIVE_NOT_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis|ALS
Interventions: DRUG: PrimeC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antidepressant Treatment in Older Adults With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Citalopram (Celexa)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Lockdown Related Telemedicine for Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DEVICE: Hospital telemedicine management system|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Sotagliflozin Versus Placebo in Patients With Type 2 Diabetes Mellitus on Background of Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Sotagliflozin (SAR439954)|DRUG: Placebo|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Study to Assess the Efficacy and Safety of Nemonoxacin Malate in Treating Adult Patients With Community-acquired Pneumonia (CAP)
Status: COMPLETED
Conditions: Community-acquired Pneumonia
Interventions: DRUG: Levofloxacin 500 mg placebol|DRUG: Levofloxacin 500 mg placebol|DRUG: Nemonoxacin 3 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention and Management of Intravesical BCG-related Lower Urinary Tract Symptoms
Status: TERMINATED
Conditions: Lower Urinary Tract Symptoms|Bladder Carcinoma|BCG
Interventions: DRUG: Pentosan Polysulfate Na 100Mg Cap|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-64232025 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-64232025 IV|DRUG: JNJ-64232025 SC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trials Using HepatoKeeper Herbal Essentials to Treat Non-alcoholic Fatty Liver Disease and Metabolic Factors
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease|Liver Fibrosis|Liver Injury
Interventions: DRUG: Ganwei|DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency and Hybrid Fractional Laser for Vaginal Rejuvenation
Status: COMPLETED
Conditions: Vaginal Atrophy
Interventions: DEVICE: IntraGen RF|DEVICE: DiVA|DEVICE: Placebo (DIVA/IntraGen combined)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of HLX20, a Human Monoclonal Antibody Targeting PD-L1Protein in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: HLX20
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sodium Glucose Co-transporter (SGLT) Inhibitors in Nonobstructive Hypertrophic Cardiomyopathy
Status: NOT_YET_RECRUITING
Conditions: Hypertrophic Cardiomyopathy Without Obstruction
Interventions: DRUG: Sotagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Finding the Optimal Aim of Correction in Opening Wedge High Tibial Osteotomy
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee|Knee Pain Chronic|Arthralgia
Interventions: PROCEDURE: Procedure: HTO using PSI aiming at 55% correction|PROCEDURE: Procedure: HTO using PSI aiming at 62% correction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of KSO-0400 in BPH Patients With LUTS
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia (BPH)
Interventions: DRUG: KSO-0400|DRUG: KSO-0400|DRUG: Silodosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate Safety, Tolerability, and Efficacy of Orally Administered OPC-67683
Status: COMPLETED
Conditions: Tuberculosis, Multidrug-Resistant
Interventions: DRUG: Delamanid|DRUG: OBR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Efficacy and Safety of Multi-focal Scleral Contact Lens
Status: NOT_YET_RECRUITING
Conditions: High Myopia
Interventions: DEVICE: Multi-focal rigid scleral contact lens|DEVICE: Rigid gas permeable contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Fedratinib in Japanese Subjects With DIPSS (Dynamic International Prognostic Scoring System)- Intermediate or High-risk Primary Myelofibrosis (PMF), Post-polycythemia Vera Myelofibrosis (Post-PV MF), or Post-essential Thrombocythemia Myelofibrosis (Post-ET MF)
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Myelofibrosis
Interventions: DRUG: Fedratinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT