pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Comparison of Single Incision Laparoscopic Cholecystectomy and Three Port Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Gallbladder Disease
Interventions: PROCEDURE: SILS cholecystectomy|PROCEDURE: TPCL cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Work of Breathing Under Extreme Hypercapnia Induced by Ventilation Insufficiency
Status: UNKNOWN
Conditions: Accident Caused by Snow Avalanche
Interventions: OTHER: extreme hypercapnia induced by ventilation insufficiency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Olaparib and Pembrolizumab in People With Triple Negative Breast Cancer (TNBC) or Hormone Receptor-positive HER2-negative Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Olaparib|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real World Study: Genotype 1 Chronic Hepatitis C Virus Treatment and Evaluation of Real World SVR and PRO
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: ombitasvir, paritaprevir/r, dasabuvir + ribavirin|DRUG: ombitasvir, paritaprevir/r, dasabuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SACRED A Prospective Research Study to Reduce Stroke in Children With Sickle Cell Anemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Sickle Cell Anemia
Interventions: DRUG: Hydroxyurea|PROCEDURE: TCD examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ciprofol Versus Propofol for Anesthesia Induction in Cardiac Surgery: A Randomized Double-blind Controlled Clinical Trial
Status: RECRUITING
Conditions: Anesthesia
Interventions: DRUG: Drug: ciprofol injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: ALT-801 in Healthy Overweight and Obese Volunteers to Study Safety and Tolerability
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: ALT-801|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Induction Technique on Postoperative Pain and Agitation
Status: COMPLETED
Conditions: Hernia, Inguinal|Cryptorchidism
Interventions: DRUG: Sevofluorane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Amphotericin B Liposome for Injection in Patients With Persistent Neutropenia and Fever
Status: UNKNOWN
Conditions: Neutropenia and Fever
Interventions: DRUG: Amphotericin B liposomes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety Study of Tung's Acupuncture for Polycystic Ovarian Syndrome
Status: COMPLETED
Conditions: Polycystic Ovarian Syndrome
Interventions: OTHER: Tung's acupuncture|DRUG: Cyproterone acetate/ethinylestradiol (CPA/EE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Adherence to Growth Hormone Therapy (GHT) With Norditropin® on Near Final Height in Patients With Growth Hormone Deficiency (GHD) and Born Small for Gestational Age (SGA)
Status: ENROLLING_BY_INVITATION
Conditions: Growth Hormone Deficiency in Children|Born Small for Gestational Age
Interventions: DRUG: Norditropin® FlexPro®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SexHealth Mobile: Integrating a Mobile Clinic and a Point-of-care Contraception Counseling and Access
Status: COMPLETED
Conditions: Contraceptive Usage|Contraception
Interventions: BEHAVIORAL: SexHealth Mobile
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: This is an Extension Study of the Roche P-trials to Investigate Safety and Effectiveness of Ocrelizumab in Participants With Multiple Sclerosis (MS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis
Interventions: DRUG: Ocrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protective Antibody Level After COVID-19 Vaccination Among Patients Under Hemodialysis
Status: COMPLETED
Conditions: Covid19|Vaccine Reaction|Hemolysis|End-stage Renal Disease
Interventions: DIAGNOSTIC_TEST: Elecsys Anti-SARS-CoV-2 S (Roche Diagnostics GmbH, Mannheim, Germany), 2) ACCESS SARS-CoV-2 IgG II (Beckman Coulter, Inc. USA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Alleviation of Cedar Pollen Induced Allergic Symptoms by Orally Taken Superfine Beta-1,3-Glucan
Status: TERMINATED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: beta-1,3-glucan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Combination Rucaparib With Nivolumab in Small Cell Lung Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Small Cell Lung Cancer
Interventions: COMBINATION_PRODUCT: Rucaparib and Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Albumin-bound Paclitaxel (Abraxane) in Combination With Carboplatin and Herceptin in Patients With Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Albumin-bound paclitaxel|DRUG: Carboplatin|DRUG: Herceptin®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Efficacy of Vitamins A and D and γ-oryzanol-fortified Canola Oil in Adults With Type 2 Diabetes
Status: UNKNOWN
Conditions: Diabetes
Interventions: DIETARY_SUPPLEMENT: fortified canola oil with vitamins A and D and γ-oryzanol|DIETARY_SUPPLEMENT: Active comparator|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Probiotic on the Plaque pH. A Randomized Double Blind Interventional Study
Status: COMPLETED
Conditions: Plaque Ph Lowering After Use of Probiotics|Caries|Gingivitis
Interventions: DIETARY_SUPPLEMENT: consumption of lozenges
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Development and Testing of a Smartphone Application to Reduce Substance Use and Sexual Risk Among Homeless Young Adults
Status: COMPLETED
Conditions: Alcohol Use|Marijuana Use|Sexual Behavior
Interventions: BEHAVIORAL: OnTrack|BEHAVIORAL: Treatment as Usual|BEHAVIORAL: Brief Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Counseling Coupled With FMT in the Treatment of Obesity and NAFLD - the DIFTOB Study
Status: ACTIVE_NOT_RECRUITING
Conditions: NAFLD|Fecal Microbiota|Gut Microbiota|Obesity|Dietary Habits|Diet|Fecal Microbiota Transplantation|Glucose Metabolism Disorders|Nutrition, Healthy
Interventions: OTHER: FMT and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized Trial of IUD Versus Hormonal Contraception in HIV-infected Women in Zambia
Status: COMPLETED
Conditions: Pregnancy|HIV Infection
Interventions: DEVICE: Copper T Intrauterine Contraceptive Device|DRUG: Hormonal Contraception
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Analysis of the Psychometric Properties of Kinematic Parameters of Locomotion Measured by Inertial Units. Validation in Healthy Volunteers and Stroke Patients
Status: RECRUITING
Conditions: Cerebral Vascular Accident
Interventions: OTHER: Analysis of the walk|OTHER: Analysis of the race|OTHER: Unipodal and bipodal jumps on flat ground
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MyVoice:Rheum Decision Aid for Women With Rheumatic Diseases
Status: COMPLETED
Conditions: Rheumatic Diseases|Physician-Patient Relations|Contraception
Interventions: OTHER: MyVoice:Rheum|OTHER: Pamphlet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Linking Somatic Mutation Rate With Baseline Exposure in East Palestine
Status: NOT_YET_RECRUITING
Conditions: Somatic Mutation
Interventions: OTHER: Survey|OTHER: Biological specimen collection|OTHER: Communications about study updates and future research opportunities|OTHER: Qualitative interview
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: MEDITOXIN® Treatment in Subject With Benign Masseteric Hypertrophy
Status: COMPLETED
Conditions: Masseter Muscle Hypertrophy
Interventions: DRUG: Meditoxin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the VIPUN Balloon Catheter 0.2 in Critically Ill Patients
Status: COMPLETED
Conditions: Critical Illness|Intolerance; Nutritional|Delayed Gastric Emptying|Gastric Motor Dysfunction
Interventions: DEVICE: VIPUN Balloon Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Randomized Placebo-controlled Phase 2 Study of Decitabine With or Without Eltrombopag in AML Patients
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Eltrombopag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Vascularized Knee Transplantation
Status: UNKNOWN
Conditions: Osteitis|Limb Salvage|Joint Deformities, Acquired|Skin Transplantation|Bone Transplantation
Interventions: PROCEDURE: knee joint transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of a Pharmacist-physician Intervention Model to Reduce High-risk Drug Use by Hospitalised Elderly Patients
Status: COMPLETED
Conditions: Potentially Inappropriate Medication Use
Interventions: PROCEDURE: Pharmacist-physician intervention to reduce high-risk medication use by elderly inpatients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Robotic Versus Open Pyeloplasty
Status: TERMINATED
Conditions: Pediatric Urology|Ureteropelvic Junction Obstruction
Interventions: PROCEDURE: Open Pyeloplasty (OP)|DEVICE: Robotic-Assisted Laparoscopic Pyeloplasty (RALP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Different Approaches of Spinal Anesthesia in Patients Undergoing Cesarean Section
Status: RECRUITING
Conditions: Post-Dural Puncture Headache|Hypotension|Spinal Shock|Hematoma|Bradycardia|Meningitis|Respiratory Failure
Interventions: PROCEDURE: Midline Approach|PROCEDURE: Paramedian Approach|PROCEDURE: Taylors approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Use of Transexamic Acid in Hip Replacement
Status: UNKNOWN
Conditions: Bleeding|Transfusion Related Complication
Interventions: DRUG: Tranexamic Acid (IV)|DRUG: Tranexamic Acid (Topical)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Esketamine on Recovery of Consciousness After Propofol Anesthesia
Status: RECRUITING
Conditions: Post-anesthesia Recovery
Interventions: DRUG: Esketamine|DRUG: Esketamine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Pilot Study of Treatment for BCC Using the Multiplex 595/1064 nm Laser
Status: COMPLETED
Conditions: Nodular Basal Cell Carcinoma|Superficial Basal Cell Carcinoma
Interventions: DEVICE: 595/1064 multiplex laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STIMULATE Study: Anemia Correction and Health-related Quality of Life (HRQoL) Outcomes in Elderly Chronic Kidney Disease (CKD) Patients
Status: TERMINATED
Conditions: Anemia|Chronic Kidney Disease
Interventions: DRUG: Darbepoetin alfa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study to Evaluate Rosacea
Status: WITHDRAWN
Conditions: Papulopustular Rosacea
Interventions: DRUG: AIV001|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Efficacy And Safety Of Intramuscular Levosulpiride In Patients With Agitation Of Schizophrenia
Status: COMPLETED
Conditions: Agitation
Interventions: DRUG: Intramuscular Haloperidol|DRUG: Intramuscular Levosulpiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Opioid Effects on Swallowing and Esophageal Sphincter Pressure
Status: COMPLETED
Conditions: Opioid Induced Pharyngeal and Esophageal Dysfunction
Interventions: DRUG: naloxone|DRUG: remifentanil|DRUG: Sodium Chloride|DRUG: metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Stem Cells Cultured on a Scaffold for the Treatment of Aneurysmal Bone Cysts (ABC)
Status: UNKNOWN
Conditions: Aneurysmal Bone Cyst
Interventions: BIOLOGICAL: MSC-PLGA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: an On-demand Program to EmpoweR Active Self-management (OPERAS)
Status: UNKNOWN
Conditions: Joint Disease|Rheumatoid Arthritis
Interventions: BEHAVIORAL: Education, Fitbit/self-management app, physiotherapist counselling.|BEHAVIORAL: Same intervention with a 6 month delay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Testing the Effectiveness of a Betel Nut Cessation Program
Status: COMPLETED
Conditions: Betel Nut Chewer|Tobacco Cessation
Interventions: BEHAVIORAL: Betel Nut Cessation Social Support|BEHAVIORAL: Betel Nut Cessation Booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 1-2, XIAP Antisense AEG35156 With Weekly Paclitaxel in Patients With Advanced Breast Cancer
Status: TERMINATED
Conditions: Human Mammary Carcinoma
Interventions: DRUG: AEG35156
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Immunotherapy Combination BN-Brachyury Vaccine, M7824, N-803 and Epacadostat (QuEST1)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Prostate Cancer|Prostate Cancer|Prostate Neoplasm|Advanced Solid Tumor|Solid Tumor
Interventions: BIOLOGICAL: M7824|DRUG: N-803|BIOLOGICAL: MVA-BN-Brachyury|BIOLOGICAL: FPV-Brachyury|DRUG: Epacadostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Dose Proton/Photon RT + Surgery of Sarcomas of the Thoracic, Lumbar Spine/Sacrum
Status: COMPLETED
Conditions: Mesenchymal Tumor
Interventions: RADIATION: Proton Beam Radiation|RADIATION: Photon Beam Radiation|RADIATION: Interoperative radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-interventional Study for Real-world Data of Afatinib Treatment in First-line Setting and of Subsequent Therapies for Patients With Advanced Epidermal Growth Factor Receptor (EGFR) Mutation-positive Lung Adenocarcinoma
Status: COMPLETED
Conditions: Non-squamous, Non-Small Cell Lung Cancer
Interventions: DRUG: afatinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: THE IMPROVE TRIAL: Improving Pain Management and Outcomes With Various Strategies of Patient-Controlled Analgesia (PCA)
Status: TERMINATED
Conditions: Sickle Cell Disease
Interventions: OTHER: High Demand / Low Infusion|OTHER: PCA Dosing Plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sublingual L-GSH Supplementation in Male Subjects With Smoking Habit and/or Hypertension
Status: COMPLETED
Conditions: Health Subjects With Cardiovascular Risk Factors
Interventions: DIETARY_SUPPLEMENT: L-GSH|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-operative Lite Run Study
Status: COMPLETED
Conditions: Cerebral Palsy|Neurologic Disorder|Chromosome Abnormality|Spina Bifida
Interventions: DEVICE: Lite Run Gait Trainer|OTHER: Usual Treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Study to Investigate the Pharmacokinetic Profile of ALXN2050 Modified Release Prototype Formulations and Immediate Release Reference Tablet in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: ALXN2050 MR Prototype Tablet|DRUG: ALXN2050 Immediate Release (IR) Tablet|DRUG: ALXN2050 MR Prototype Mini-Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Topical Bromfenac Versus Placebo to Treat Ocular Inflammation After Cataract Surgery
Status: COMPLETED
Conditions: Postoperative Complications|Cataract
Interventions: DRUG: Bromfenac|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety, Dose Tolerance, Pharmacokinetics, and Pharmacodynamics Study of CPX-POM in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumor
Interventions: DRUG: CPX-POM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Empagliflozin Added to Automated Insulin Delivery (AID) Systems in Adults With Type 1 Diabetes With Sub-optimal Glycemic Outcomes
Status: RECRUITING
Conditions: Type 1 Diabetes
Interventions: DRUG: Empagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S-1, Oxaliplatin, and Irinotecan for Advanced Gastrointestinal Cancer
Status: COMPLETED
Conditions: Gastrointestinal Neoplasms
Interventions: DRUG: OIS (Oxaliplatin, Irinotecan, S-1)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir Co-Administered With Sofosbuvir With and Without Ribavirin in Treatment-Naive HCV Genotype 1-Infected Adults
Status: COMPLETED
Conditions: Chronic Hepatitis C Virus (HCV Infection Genotype 1)
Interventions: DRUG: ombitasvir/paritaprevir/ritonavir, dasabuvir|DRUG: sofosbuvir (SOF)|DRUG: ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Capmatinib + Spartalizumab in Advanced Oesogastric Adenocarcinoma
Status: SUSPENDED
Conditions: Oesophageal Adenocarcinoma|Gastric Adenocarcinoma
Interventions: DRUG: Capmatinib|DRUG: Spartalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy, Safety and Tolerability of AKB-9778 Ophthalmic Solution as and Adjunct to Latanoprost in Patients With Ocular Hypertension or Open Angle Glaucoma
Status: COMPLETED
Conditions: Ocular Hypertension|Primary Open Angle Glaucoma
Interventions: DRUG: Latanoprost ophthalmic solution|DRUG: AKB-9778 4%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for CKD
Status: RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: BIOLOGICAL: AlloRx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apokyn for Motor IMProvement of Morning AKinesia Trial (AM IMPAKT)
Status: COMPLETED
Conditions: Parkinson's Disease|Motor Symptoms|Akinesia|Hypomobility|Delayed Levodopa Onset
Interventions: DRUG: APOKYN|DRUG: L-dopa|DRUG: Trimethobenzamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurocognitive Robot-assisted Rehabilitation of Hand Function After Stroke
Status: COMPLETED
Conditions: Stroke|Upper Extremity Paresis
Interventions: DEVICE: robot-assisted neurocognitive therapy of hand function|OTHER: Conventional neurocognitive rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dress for Success: Can Just Dressing for the Gym Help Going to the Gym?
Status: COMPLETED
Conditions: Healthy
Interventions: BEHAVIORAL: Take and send a selfie|BEHAVIORAL: Workout gears|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal Samples
Status: RECRUITING
Conditions: Barrett Esophagus|Barretts Esophagus With Dysplasia|Barrett's Esophagus Without Dysplasia|Esophageal Adenocarcinoma
Interventions: DEVICE: Cytosponge Procedure|DIAGNOSTIC_TEST: Endoscopic Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study of Improving Gait Parameters When Using a Cane in "Light Touch" Condition in Elderly People With and Without Walking Difficulties
Status: UNKNOWN
Conditions: Disorders of Balance
Interventions: OTHER: postural task|OTHER: walk task
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparison Of The 3M TM S Surgical Skin Closure System To The Standard Vicryl Suture Closure of Sternotomy Incisions During Cardiac Surgery
Status: COMPLETED
Conditions: Wound Infection
Interventions: PROCEDURE: Vicryl Suture|DEVICE: 3M TM S Surgical Skin Closure System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cell Transplantation for Refractory Primary Biliary Cholangitis
Status: UNKNOWN
Conditions: Primary Biliary Cirrhosis
Interventions: PROCEDURE: mesenchymal stem cell transplantation or placebo infusion via peripheral vein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Multiple Doses of Canakinumab (ACZ885) in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Canakinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 1 Study of ANAVEX3-71
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ANAVEX3-71|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of RTXM83 Plus CHOP Chemotherapy Versus a Rituximab Plus CHOP Therapy in Patients With Non Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B-cell Lymphoma
Interventions: BIOLOGICAL: RTXM83|BIOLOGICAL: Mabthera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence, Predictors and Management of Gastroesophageal Reflux After Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: PROCEDURE: patients with GERD after LSG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Modified-free Gingival Graft for Treatment of Localized Gingival Recession Defects
Status: COMPLETED
Conditions: Gingival Recession, Localized
Interventions: PROCEDURE: Mucogingival surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: How Body Awareness Promotes Mental Health During Yoga and Physical Exercise
Status: COMPLETED
Conditions: Negative Thoughts|Mild Depression|Stress
Interventions: BEHAVIORAL: Gentle Yoga Intervention|BEHAVIORAL: Rigorous Yoga Intervention|BEHAVIORAL: Physical Exercise Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of the Safety and Efficacy of Fixed Dose OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder (the Pyxis Trial)
Status: COMPLETED
Conditions: Depressive Disorder|Depression|Depressive Disorder, Major|Mood Disorders|Mental Disorders
Interventions: DRUG: OPC-34712 + ADT|DRUG: Placebo + ADT|DRUG: Placebo + ADT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study in Parkinson's Disease Patients With Dyskinesia With Combinations of JM-010 and Its Individual Components
Status: TERMINATED
Conditions: Dyskinesias|Parkinson Disease
Interventions: DRUG: Part 1, JM-010 component Group A|DRUG: Part 1, JM-010 component Group B|DRUG: Part 1, JM-010 component Group C|DRUG: Part 1, Placebo Group|DRUG: Part 2, JM-010 combination Group A|DRUG: Part 2, JM-010 combination Group B|DRUG: Part 2, JM-010 component Group C|DRUG: Part 2, Placebo Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Efficacy of AZD1236 in Patients With Cystic Fibrosis
Status: WITHDRAWN
Conditions: Cystic Fibrosis
Interventions: DRUG: AZD1236|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Kinesio Taping in Women With Primary Dysmenorrhea
Status: UNKNOWN
Conditions: Primary Dysmenorrhea
Interventions: OTHER: Kinesio tape application|OTHER: Sham Kinesio tape application|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Regorafenib on Digoxin and Rosuvastatin in Patients With Advanced Solid Malignant Tumors.
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Digoxin|DRUG: Rosuvastatin|DRUG: Regorafenib (Stivarga, BAY73-4506)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of Enzalutamide in Patients With Localized Prostate Cancer Undergoing Active Surveillance
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Enzalutamide|OTHER: Active Surveillance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-Exposure Prophylaxis to Prevent HIV-1 Acquisition Within HIV-1 Discordant Couples
Status: COMPLETED
Conditions: HIV-1 Infections|HIV Infections
Interventions: DRUG: Tenofovir Disoproxil Fumarate (TDF)|DRUG: Emtricitabine/Tenofovir Disoproxil Fumarate (FTC/TDF)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of SRD441 Ointment in Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: OTHER: Vehicle ointment|DRUG: Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of a Cortivazol (ALTIM®) Infiltration of Posterior Epidural Space at L3-L4 Stage Versus an Epidural Infiltration of Cortivazol (ALTIM®) on Contact With Disco Radicular Conflict in Discal Sciatica
Status: UNKNOWN
Conditions: Discal Sciatica
Interventions: PROCEDURE: Non target epidural infiltration done at L3-L4 stage|PROCEDURE: Epidural infiltration on contact of disco radicular conflict
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Eribulin in the Treatment of Advanced Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Eribulin|DRUG: Trastuzumab|DRUG: pertuzumab|DRUG: Pyrotinib|DRUG: Pembrolizumab|DRUG: Camerlizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Duration of Ropivacaine Combined With Dexmedetomidine or Dexamethasone on Paravertebral Block
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Dexmedetomidine Group|DRUG: dexamethasone group|DRUG: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Interleukin-1 in the Regulation of Muscle Derived Interleukin-6 During Exercise
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: IL-1Ra|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Proof of Concept Anti-ageing Clinical Study in Healthy Subjects
Status: COMPLETED
Conditions: Skin Aging
Interventions: OTHER: Test product (Moisturising cream)|OTHER: Positive control (Commercial market place moisturising cream)|OTHER: No treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Double-blind, Randomized, Controlled, Roll-over Retreatment Study of the Safety and Pain Associated With Injections of PN40082, RV001 With Topical Anesthetic or RV001 for Lip Augmentation
Status: TERMINATED
Conditions: Lip Augmentation
Interventions: DEVICE: PN40082
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: C-TPF in Patients With Newly Diagnosed Locally Advanced Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Head and Neck Neoplasms
Interventions: DRUG: Cetuximab|DRUG: Docetaxel|DRUG: Cisplatin|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mass Spectrometry-based Proteomics in Microvascular Inflammation Diagnosis in Kidney Transplantation.
Status: RECRUITING
Conditions: Kidney Transplantation|Graft Rejection|Humoral Immunity|Proteomics
Interventions: DIAGNOSTIC_TEST: Mass spectrometry-based proteomics of FFPE biopsies and urine samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial of M4344 and Niraparib in Patients With Poly (ADP-ribose) Polymerase (PARP) Resistant Recurrent Ovarian Cancer
Status: WITHDRAWN
Conditions: Ovarian Cancer Recurrent
Interventions: DRUG: M4344+Niraparib|DRUG: M4344+Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calcium-41 (41Ca) Chloride Aqueous Solution in Diagnosing Patients With Prostate Cancer and Bone Metastasis
Status: TERMINATED
Conditions: Metastatic Cancer|Prostate Cancer
Interventions: DRUG: 41 Ca
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Early Use of Vasopressin in Post-Fontan Management
Status: COMPLETED
Conditions: Circulatory Perfusion Disorder|Congenital Heart Disease|Single-ventricle
Interventions: DRUG: Vasopressin, Arginine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Emotional Freedom Technique on Breastfeeding Success and Self-Efficacy
Status: RECRUITING
Conditions: Breastfeeding|Self Efficacy|Cesarean Delivery Affecting Fetus|First Birth
Interventions: OTHER: emotional freedom technique experimental group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Drug to Drug Interaction Study With ASP1941 and Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ASP1941|DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Activity and Balanced Eating to Reduce Comorbidities and Symptoms of MS
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Behavioral Intervention for Physical Activity in Multiple Sclerosis (BIPAMS)|BEHAVIORAL: BIPAMS + Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ciclesonide on Small Airways in Patients With Stable Asthma (18 to 60 y) (BY9010/M1-131)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Ciclesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Electroacupuncture Frequency-related Effects on Non-specific Low Back Pain in Older Adults.
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: PROCEDURE: Electroacupuncture|DEVICE: Needle|DEVICE: Adhesive Moxa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CopenHeartRFA - Integrated Rehabilitation of Patients Treated for Atrial Fibrillation With Radio Frequency Ablation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: BEHAVIORAL: Rehabilitation|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Eltrombopag Combined With Cyclosporine as First Line Therapy in Patients With Severe Acquired Aplastic Anemia
Status: COMPLETED
Conditions: Severe Aplastic Anemia
Interventions: DRUG: eltrombopag|DRUG: Cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of The Efficacy And Safety Of Pregabalin Compared To Placebo For Treatment Of Post-Surgical Pain From Hysterectomy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: pregabalin (Lyrica)|DRUG: pregabalin (Lyrica)|DRUG: matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Bioavailability Study of Two Different PEG-rhGH Preparations.
Status: NOT_YET_RECRUITING
Conditions: Pediatric Growth Hormone Deficiency (PGHD)
Interventions: DRUG: PEG-rhGH with new preparation (T)|DRUG: PEG-rhGH with present preparation (R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: AnGiographic Performance With A Sirolimus-elutiNG Balloon in the TrEatment of De Novo CoronaRy Artery Disease
Status: RECRUITING
Conditions: Coronary Restenosis
Interventions: DEVICE: Magic Touch SCB by Concept Medical Inc.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ILX-295501 in Treating Patients With Stage III or Stage IV Ovarian Cancer That Has Not Responded to Previous Treatment
Status: WITHDRAWN
Conditions: Fallopian Tube Cancer|Metastatic Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: ILX-295501
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Aminocamptothecin in Treating Patients With Refractory or Recurrent Hodgkin's Disease or Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: aminocamptothecin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prognostic Influence of Light Rheography Measurement of Patients With Secondary Raynaud Syndrome With Ulcers on Hands
Status: UNKNOWN
Conditions: Raynaud's Phenomenon|Skin Necrosis
Interventions: DRUG: Tracleer|DRUG: Prostavasin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of the Prevalence of Iron Deficiency in Patients With Chronic Renal Failure But Non-Dialysis (CARENFER IRC-ND)
Status: UNKNOWN
Conditions: Chronic Kidney Diseases
Interventions: DIAGNOSTIC_TEST: Iron status testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Physical Therapy vs Surgical Decompression for Lumbar Spinal Stenosis
Status: RECRUITING
Conditions: Spinal Stenosis
Interventions: PROCEDURE: surgery|BEHAVIORAL: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Lipid Soluble Opioids for Gynecologic Laparoscopic Surgery Postoperative Patient-controlled Analgesia
Status: COMPLETED
Conditions: Post Operative Pain Management
Interventions: DRUG: Sufentanil (R30730, brand name Sufenta)|DRUG: Sufentanil (R30730, brand name Sufenta) + Morphine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating the Effects of a Novel Mindfulness Approach on Frequency and Duration of Meditation and Self-Reported Stress and Mood in Generally Healthy Adults
Status: COMPLETED
Conditions: Health Knowledge, Attitudes, Practice
Interventions: OTHER: Meditation with guided tea consumption|OTHER: Breathing meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of Bariatric Surgery on Heart Disease Compared to Standard Care
Status: NOT_YET_RECRUITING
Conditions: Obesity, Morbid|Bariatric Surgery Candidate|Heart Diseases
Interventions: PROCEDURE: Bariatric surgery|PROCEDURE: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Initiating and Maintaining Physical Activity in Depressed Individuals
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: BA (brief advice)|BEHAVIORAL: SHE (supervised and home-based exercise)|BEHAVIORAL: HE (health education)|BEHAVIORAL: CBEX (cognitive-behavioral sessions focused on increasing and maintaining exercise)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 26 Weeks' Dietary Supplementation With DHA- and EPA-enriched Oils on Cerebral Blood Flow in Healthy Adults
Status: COMPLETED
Conditions: Neurovascular Coupling
Interventions: DIETARY_SUPPLEMENT: Olive oil Placebo|DIETARY_SUPPLEMENT: EPA-rich|DIETARY_SUPPLEMENT: DHA-rich
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Investigate How JNJ-39758979 May Affect the Plasma Levels of Methotrexate in Rheumatoid Arthritis Participants
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: JNJ-39758979 / MTX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topiramate for Alcohol and Cocaine Dependence
Status: COMPLETED
Conditions: Alcoholism|Cocaine Dependence
Interventions: DRUG: Topiramate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Citalopram for Children With Autism and Repetitive Behavior (STAART Study 1)
Status: COMPLETED
Conditions: Autistic Disorder
Interventions: DRUG: citalopram hydrobromide|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Lesion Preparation With Non-compliant Balloons Before Implantation Of Bioresorbable Scaffolds
Status: COMPLETED
Conditions: Coronary Artery Disease|Angina, Unstable|Angina, Stable
Interventions: DEVICE: OPN strategy|DEVICE: standard strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CoROnary SinuS Reducer implantatiOn for ischemiA reDuction
Status: COMPLETED
Conditions: Refractory Angina Pectoris
Interventions: DEVICE: Coronary Sinus Reducer device|OTHER: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Vitamin B6 and B12 in the Treatment of Movement Disorders Induced by Antipsychotics
Status: UNKNOWN
Conditions: Schizophrenia|Drug Induced Movement Disorder, Unspecified|Oxidative Stress
Interventions: DRUG: Pyridoxine|DRUG: Cobalamin|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of T0903131 (INT131) Besylate to Treat Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type II
Interventions: DRUG: T0903131 Besylate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ezetimibe on Oxidized Low-density Lipoprotein (LDL) Cholesterol
Status: COMPLETED
Conditions: Coronary Artery Disease|Diabetes
Interventions: DRUG: ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT