pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study to Evaluate the Pharmacokinetics (PK) and Safety/Tolerability of Long-Acting Oral LYN-005
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: LYN-005|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of NY-ESO-1 Overlapping Peptides in Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: BIOLOGICAL: NY-ESO-1 OLP4|BIOLOGICAL: NY-ESO-1 OLP4 + Montanide|BIOLOGICAL: NY-ESO-1 OLP4 + Montanide + Poly-ICLC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Nurse-led Family Intervention on Stress, Engagement With Patient's Care and Satisfaction Among Primary Caregivers of Chronic Liver Disease Patients Admitted in High Dependency Unit of ILBS, New Delhi
Status: UNKNOWN
Conditions: Family Members of the Patients
Interventions: OTHER: Nurse-led family intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exposure Therapy for Chronic PTSD: Efficacy and Mechanisms
Status: COMPLETED
Conditions: Combat Disorders|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Prolonged Exposure therapy for PTSD|BEHAVIORAL: Present centered therapy for PTSD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder for Bladder Cancer Treatment, MODERN Study
Status: RECRUITING
Conditions: Muscle Invasive Bladder Urothelial Carcinoma|Stage II Bladder Urothelial Carcinoma AJCC v6 and v7|Stage III Bladder Urothelial Carcinoma AJCC v6 and v7|Stage IV Bladder Urothelial Carcinoma AJCC v7
Interventions: PROCEDURE: Biospecimen Collection|OTHER: cfDNA or ctDNA Measurement|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Nivolumab|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|BIOLOGICAL: Relatlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ivosidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH1
Status: RECRUITING
Conditions: Clonal Cytopenia of Undetermined Significance
Interventions: DRUG: Ivosidenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Finding Study in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)(174007/P05805/MK-8777-003)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: MK-8777|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Activation for Independence in Older Veterans
Status: RECRUITING
Conditions: Functional Independence
Interventions: BEHAVIORAL: Behavioral Activation for Independence in Older Veterans (ACTIVaTE)|BEHAVIORAL: Attention control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the 3-in-1 Neuroguard IEP System for Carotid Artery Stenosis
Status: COMPLETED
Conditions: Carotid Artery Stenosis
Interventions: DEVICE: Neuroguard® IEP 3-in-1 Carotid Stent and Post-Dilation Balloon System with Integrated Embolic Protection (Neuroguard IEP System)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Block for Laparoscopic Appendicectomy in Children
Status: UNKNOWN
Conditions: Laparoscopic Appendectomy
Interventions: OTHER: TAP block with Ropivacaine|DRUG: Curare
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Docetaxel With a Phytochemical in Treating Patients With Hormone Independent Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: phytochemical|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Vitamin D in the Elderly
Status: COMPLETED
Conditions: Deficiency of Vitamin D3
Interventions: DIETARY_SUPPLEMENT: D3 2000 IU/day|DIETARY_SUPPLEMENT: D3 4000 IU/day|DIETARY_SUPPLEMENT: D3 50,000 IU weekly|DIETARY_SUPPLEMENT: vitamin D3 800 IU/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Comparison of Two Different Optical Biometric Systems
Status: RECRUITING
Conditions: Cataract|Presbyopia|Ocular Biometry|Intraocular Lens
Interventions: DEVICE: Argos (Alcon Laboratories, Inc.)|DEVICE: IOLMaster 500 (Carl Zeiss Meditec AG)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Behavior Change Communication About Improved Micronutrient Intake on Nutritional Status and Academic Performance of School Age Children in Meskan District, Gurage Zone, South Ethiopia
Status: UNKNOWN
Conditions: Child Nutrition Disorders
Interventions: BEHAVIORAL: BCC on Essential Nutrition and Hygiene Actions (ENHAs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Simvastatin in Chronic Obstructive Pulmonary Disease (COPD)
Status: UNKNOWN
Conditions: COPD|Emphysema
Interventions: DRUG: Simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Tart Cherry Juice Supplementation With Metabolic Syndrome Participants
Status: COMPLETED
Conditions: Metabolic Syndrome|Insulin Resistance|Hypertension
Interventions: DIETARY_SUPPLEMENT: Montmorency Tart Cherry Juice|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Relation Between Mixed Venous Oxygen Saturation and Cerebral Oxygen Saturation Measured by Absolute and Relative Near-infrared Spectroscopy During Off-pump Coronary Artery Bypass Grafting.
Status: COMPLETED
Conditions: Elective Off-pump Coronary Artery Bypass Grafting
Interventions: PROCEDURE: Relative and absolute cerebral oxygen saturation (rScO2) measurements.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: D2 Versus D1 Gastrectomy of Operable Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: PROCEDURE: Radical gastrectomy with D1 lymphadenectomy|PROCEDURE: Radical gastrectomy with D2 lymphadenectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Geriatric Assessment Intervention for Reducing Toxicity in Older Patients With Advanced Cancer
Status: COMPLETED
Conditions: Adult Solid Neoplasm|Toxicity|Lymphoma
Interventions: OTHER: Comprehensive Geriatric Assessment|OTHER: Quality-of-Life Assessment|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Nociception Level Monitoring During Remimazolam-based Total Intravenous Anesthesia on Intraoperative Opioid Requirements and Postoperative Pain
Status: RECRUITING
Conditions: Adult Patients Aged 19-64, Scheduled for Elective Arthroscopic Knee Surgery
Interventions: DEVICE: Analgesia Nociception Index monitor|DEVICE: Standard monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: ABY-035 in the Treatment of Subjects With Ankylosing Spondylitis
Status: TERMINATED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: ABY-035|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety And Efficacy Study Of Orally Administered DS102 In Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: DS102|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Efficacy and Safety of Enzyme Replacement Therapies Avalglucosidase Alfa and Alglucosidase Alfa Administered Every Other Week in Patients With Late-onset Pompe Disease Who Have Not Been Previously Treated for Pompe Disease
Status: COMPLETED
Conditions: Glycogen Storage Disease Type II;Pompe's Disease
Interventions: DRUG: Avalglucosidase alfa (GZ402666)|DRUG: Alglucosidase alfa (GZ419829)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy for Post-Traumatic Stress Disorder in Individuals With Severe Mental Illness
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Schizophrenia
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Damage Control Laparotomy
Status: COMPLETED
Conditions: Other Injury of Other Intra-abdominal Organs, Initial Encounter
Interventions: PROCEDURE: Definitive Closure Laparotomy|PROCEDURE: Damage Control Laparotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Church-based Intervention to Improve Physical Function in African Americans
Status: RECRUITING
Conditions: Physical Function|Multiple Chronic Conditions
Interventions: BEHAVIORAL: Keep it Movin'|BEHAVIORAL: Go 4 Life Self Guided Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Irritable Bowel Syndrome Evaluation and Treatment in Primary Care
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Bifidobacterium infantis|DRUG: Pancrelipase|DRUG: Nitazoxanide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Vitamin D3 for the Treatment of Psoriatic Patients With Vitamin D Deficiency and Insufficiency
Status: UNKNOWN
Conditions: Psoriasis Vulgaris|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety & Health Improvement: Enhancing Law Enforcement Departments
Status: COMPLETED
Conditions: Physical Activity|Nutrition|Health Promotion|Stress, Psychological|Cardiovascular Diseases|Cancer
Interventions: BEHAVIORAL: Behavioral: Team-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ganetespib and Ziv-Aflibercept in Refractory Gastrointestinal Carcinomas, Non-Squamous Non-Small Cell Lung Carcinomas, Urothelial Carcinomas, and Sarcomas
Status: TERMINATED
Conditions: Neoplasms
Interventions: DRUG: Ziv-Aflibercept|DRUG: Ganetespib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Extract of Green Tea on Obese Women and Obese Related Hormone Peptides
Status: UNKNOWN
Conditions: Diabetes Mellitus|Hyperlipidemia
Interventions: DRUG: EGCG(Epigallocatechin Gallate)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bipolar Study of Seroquel XR With Pramipexole Dihydrochloride
Status: COMPLETED
Conditions: Bipolar Depression
Interventions: DRUG: quetiapine (Seroquel) XR|DRUG: quetiapine (Seroquel) XR|DRUG: placebo|DRUG: pramipexole dihydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Intervention in Primary Health Care - the Björknäs Study
Status: COMPLETED
Conditions: Hypertension|Type 2 Diabetes|Obesity|Dyslipidemia
Interventions: BEHAVIORAL: Exercise and diet - based on DPS and DPP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Early Feasibility Study 2 of Outpatient Control-to-Range - Testing System Efficacy (France)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Diabetes Assistant (DiAs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kaleidoscope Virtual Reality Glasses Pain and Anxiety Levels in Venous Blood Collection Children
Status: NOT_YET_RECRUITING
Conditions: Child, Only
Interventions: OTHER: Kaleidoscope|OTHER: Virtual Reality|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Dapagliflozin 10 mg on Insulin Resistance in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BOTOX® Open-Label Treatment in Pediatric Lower Limb Spasticity
Status: COMPLETED
Conditions: Pediatrics|Muscle Spasticity|Cerebral Palsy
Interventions: BIOLOGICAL: Botulinum Toxin Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Healthy Volunteer Study of PBI-4050
Status: COMPLETED
Conditions: Fibrosis|Inflammation
Interventions: DRUG: PBI-4050/ Placebo|DRUG: PBI-4050/ Placebo|DRUG: PBI-4050/ Placebo|DRUG: PBI-4050/ Placebo|DRUG: PBI-4050/ Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MP1032 Treatment in Patients With Moderate to Severe COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: MP1032|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Heparin and Tocilizumab in Patients With Severe COVID-19 Infection
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Tocilizumab|DRUG: Heparin - Therapeutic dosage|DRUG: Heparin - Prophylactic dosage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer (NSCLC)|Colorectal Cancer (CRC)|Pancreatic Ductal Adenocarcinoma (PDAC)|Advanced Solid Tumors
Interventions: DRUG: RMC-9805|DRUG: RMC-6236
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Xeloda (Capecitabine) as First-Line Chemotherapy in Patients With Advanced or Metastatic Gastric Cancer.
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Oxaliplatin|DRUG: capecitabine [Xeloda]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Lumen- Apposing, Covered, Self-Expanding Metal Stent (Axios™) Versus Multiple Double Pigtail Stents
Status: TERMINATED
Conditions: Pancreatic Necrosis
Interventions: DEVICE: AXIOS™ stent|DEVICE: Double Pigtail Stents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Imaging of Breast Cancer With Indocyanine Green
Status: COMPLETED
Conditions: Invasive Ductal Carcinoma|Invasive Lobular Carcinoma|Ductal Carcinoma
Interventions: DRUG: Indocyanine Green
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Pregabalin Versus Placebo in the Treatment of Nerve Pain Associated With HIV Neuropathy
Status: COMPLETED
Conditions: HIV Infections|Peripheral Neuropathy
Interventions: DRUG: pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating the Efficacy of GON Blocks.
Status: COMPLETED
Conditions: Migraine|Chronic Migraine, Headache
Interventions: DRUG: Combined Depo-Medrone and Lidocaine|DRUG: Sodium Chloride 0.9% Inj
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dinner Time for Obesity and Prediabetes
Status: RECRUITING
Conditions: PreDiabetes|Obesity|Healthy
Interventions: BEHAVIORAL: Early Dinner|BEHAVIORAL: Late Dinner|DRUG: Early Dinner tracer|DRUG: Late Dinner tracer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: FOLFOX or CAPOX Perioperative Chemotherapy Versus Postoperative Chemotherapy for Locally Advanced Colon Cancer (OPTICAL)
Status: UNKNOWN
Conditions: Colon Cancer
Interventions: DRUG: Perioperative chemotherapy with mFOLFOX6 or CAPOX regimens|DRUG: Postoperative chemotherapy with mFOLFOX6 or CAPOX regimens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Double-blind, Placebo-controlled Study of AZD7442
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: AZD7442 300 mg IM(male)|BIOLOGICAL: AZD7442 600 mg IM (male)|BIOLOGICAL: AZD7442 300 mg IV (male and female)|BIOLOGICAL: AZD7442 1000 mg IV (male)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Does the Use of Continuous Glucose Monitoring (CGM) in the Immediate Postpartum Period in Women With Pregestational Diabetes Admitted to the Hospital Decrease Hypoglycemic Episodes
Status: RECRUITING
Conditions: Pregestational Diabetes
Interventions: DEVICE: CGM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparing 3 Antibiotic Regimes for Erythema Migrans in General Practice
Status: COMPLETED
Conditions: Erythema Migrans|Erythema Chronicum Migrans|Borreliosis|Lyme Disease|Early Lyme Disease
Interventions: DRUG: Doxycycline|DRUG: Phenoxymethylpenicillin|DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Demonstrate the Efficacy and Safety of Propranolol Oral Solution in Infants With Proliferating Infantile Hemangiomas Requiring Systemic Therapy
Status: COMPLETED
Conditions: Infantile Hemangioma
Interventions: DRUG: Propranolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Smoking and Ventricular Repolarization
Status: COMPLETED
Conditions: Sudden Cardiac Death|Prolonged QTc Interval
Interventions: OTHER: EC with nicotine|OTHER: EC without nicotine|OTHER: control|OTHER: TC with nicotine (own brand)|OTHER: research TC with very low level nicotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Radiation Therapy and Cisplatin With or Without Cetuximab in Treating Patients With Stage III or Stage IV Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: cetuximab|DRUG: cisplatin|RADIATION: Accelerated Fractionation by Concomitant Boost|RADIATION: Intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Noraxon myoRESEARCH™ Software Gait Analysis Evaluation and Orthotic Gait Correction in Reducing Diabetic Foot Ulceration Or Subsequent Amputation in Patients With a History of a Diabetic Foot Ulceration
Status: RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: Noraxon myoRESEARCH™ Software Gait Analysis Evaluation and Orthotic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Activity, Insulin Resistance and Function of Fat Tissue in the Offspring of Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Cardiovascular Diseases
Interventions: BEHAVIORAL: Physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Hip Fracture and Spinal Anaesthesia Injection Time
Status: NOT_YET_RECRUITING
Conditions: Hypotension|Hip Fractures|Anesthesia
Interventions: DRUG: Norepinephrine 1 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Postprandial Plasma Amino Acid Concentrations After Dairy Consumption
Status: COMPLETED
Conditions: Protein Digestion Kinetics
Interventions: OTHER: skimmed milk (UHT)|OTHER: skimmed milk (pasteurized)|OTHER: skimmed yoghurt|OTHER: full-fat milk (UHT)|OTHER: non-homogenized full-fat milk (pasteurized)|OTHER: full-fat cheese (semi-matured)|OTHER: whey protein|OTHER: micellar casein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioavailability of GDC-0134 and the Effect of Food and Proton Pump Inhibitor on Pharmacokinetics of GDC-0134 in Healthy Female Participants
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Reference capsule GDC-0134|DRUG: Prototype capsule GDC-0134|DRUG: rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microvascular Plug (MVP) for the Treatment of Pulmonary ArterioVenous Malformations (PAVMs)
Status: COMPLETED
Conditions: Pulmonary Arteriovenous Malformation
Interventions: DEVICE: Microvascular Plug (MVP)|DEVICE: Amplatzer Vascular Plug (AVP)|DEVICE: Detachable coils
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Characterize the Nicotine Uptake and Subjective Effects With Use of JUUL Electronic Nicotine Delivery Systems
Status: COMPLETED
Conditions: Electronic Cigarette Use|Tobacco Smoking
Interventions: OTHER: JUUL ENDS, Combustible cigarette, comparator e-cigarette, Nicorette gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Early Versus Very Early Postnatal Discharge on Hospital Readmissions in Newborns
Status: COMPLETED
Conditions: Hospital Readmission|Newborn Morbidity|Newborn Complication|Newborn
Interventions: OTHER: Time to discharge less than 24 hours|OTHER: Discharge time between 24 and 48 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate Effectiveness of Imiquimod 5% Cream in Superficial Basal Cell Carcinoma
Status: COMPLETED
Conditions: Basal Cell Carcinoma
Interventions: DRUG: imiquimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Indena's Virtiva® Plus Ginkgo Biloba Extract on Stress, and Cognitive Performance
Status: NOT_YET_RECRUITING
Conditions: Stress|Mood|Cognitive Change
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of FS VH S/D 4 S-apr for Flap Adherence in Rhytidectomy
Status: COMPLETED
Conditions: Face-lift|Facial Rhytidectomy
Interventions: BIOLOGICAL: FS VH S/D 4 s-apr
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess BMS-986460 in Participants With Metastatic Castration-resistant Prostate Cancer
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: BMS-986460
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 24-Week Efficacy & Safety Study of Brisdelle™ (Formerly Known as Mesafem) in the Treatment of Vasomotor Symptoms
Status: COMPLETED
Conditions: Hot Flashes
Interventions: DRUG: Brisdelle (paroxetine mesylate)|DRUG: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating of the Efficacy and Safety of Vardenafil in Subjects With Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Corrective Exercises and Postural Education on Forward Head Posture
Status: COMPLETED
Conditions: Musculoskeletal Deformity
Interventions: OTHER: Corrective Exercises|OTHER: Postural Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Thioldisulfide Balance in Cervical Preinvasive Lesions
Status: COMPLETED
Conditions: Oxidative Stress|Low Grade Squamous Intraepithelial Lesion|High-Grade Squamous Intraepithelial Lesions
Interventions: DIAGNOSTIC_TEST: Disulphide(μmol/L)|DIAGNOSTIC_TEST: Total Oxidant Capacity(μmolH2O2Equiv/L)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Letrozole With Lerociclib Versus Letrozole With Placebo Control in Patients With Advanced/Metastatic or Recurrent, Grade 1 or Grade 2 Endometrial Cancer
Status: WITHDRAWN
Conditions: Endometrial Carcinoma
Interventions: DRUG: Lerociclib|DRUG: Letrozole 2.5mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treadmill With Biofeedback on Gait Symmetry After Stroke
Status: UNKNOWN
Conditions: Stroke Syndrome
Interventions: OTHER: Treadmill with auditory feedback|OTHER: Treadmill with visual feedback|OTHER: Treadmill with auditory and visual feedback|OTHER: Treadmill training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Folfox+Irinotecan+Chemort In Esophageal Cancer
Status: RECRUITING
Conditions: Gastroesophageal Junction Adenocarcinoma|Esophagogastric Cancer
Interventions: DRUG: FOLFOX/ nal-IRI|DRUG: Paclitaxel|DRUG: Carboplatin|RADIATION: Proton Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Curcumin Therapy to Treat Vascular Dysfunction in Children and Young Adults With ADPKD
Status: COMPLETED
Conditions: Polycystic Kidney, Autosomal Dominant
Interventions: DRUG: Curcumin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iduronate-2-sulfatase Enzyme Replacement Therapy in Mucopolysaccharidosis II (MPS II)
Status: COMPLETED
Conditions: Mucopolysaccharidosis II
Interventions: BIOLOGICAL: Iduronate-2-sulfatase enzyme replacement therapy|BIOLOGICAL: iduronate-2-sulfatase enzyme replacement therapy|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Levodopa 250 mg and Carbidopa 25 mg With Regards to Reference Product
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Levodopa 250mg and Carbidopa 25mg Test Drug tablet|DRUG: Levodopa 250mg and Carbidopa 25mg Referent Product tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acetylsalicylic Acid Plus Intensive Blood Pressure Treatment in Patients With Unruptured Intracranial Aneurysms
Status: UNKNOWN
Conditions: Unruptured Intracranial Aneurysms
Interventions: DRUG: Acetylsalicylic acid|OTHER: intensive blood pressure control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 1 Study of Epetraborole Tablets
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Epetraborole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Laparoscopic Versus Open Liver Resection in the Treatment of Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Laparoscopic liver resection|PROCEDURE: Open liver resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhalation Intervention for Nausea in the Emergency Department
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: OTHER: Alcohol prep pad group|OTHER: Normal Saline prep pad
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Wound Contamination During Orthopaedic Surgery
Status: UNKNOWN
Conditions: Surgical Site Infection|Hip Fractures|Orthopedic Disorder|Implant Infection
Interventions: DEVICE: Conventional ventilation + instrumental tables with integrated laminar airflow|DEVICE: Conventional ventilation + standard instrumental tables|DEVICE: Laminar airflow ventilation + standard instrumental tables
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Induction Chemotherapy of TPX in Nomogram-predicted High Risk Locoregionally Advanced Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Docetaxel|DRUG: Cisplatin 1|DRUG: Xeloda|RADIATION: IMRT|DRUG: Cisplatin 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Necessity of a Second Transurethral Resection in High-risk Non-muscle-invasive Bladder Cancer Patients With Negative Urine Biomarker After Initial Transurethral Resection
Status: RECRUITING
Conditions: Non Muscle Invasive Bladder Cancer
Interventions: PROCEDURE: Urine biomarker -Guided without reTURBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Indwelling Urinary Catheterization Versus Clean Intermittent Catheterization for the Short-term Management of Hospitalized Patients With Transient Acute Urinary Retention
Status: COMPLETED
Conditions: Urinary Retention
Interventions: PROCEDURE: Indwelling urethral catheterization (Foley)|PROCEDURE: Clean intermittent catheterization (CIC)|DEVICE: Foley
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Immunogenicity of Influenza and COVID-19 Combination Vaccine
Status: COMPLETED
Conditions: SARS-CoV Infection|Covid19
Interventions: BIOLOGICAL: ICC Vaccine|BIOLOGICAL: qNIV Nanoparticle Vaccine2 in-clinic mixed with Matrix-M1 Adjuvant|BIOLOGICAL: SARS-CoV-2 rS Nanoparticle Vaccine in-clinic mixed with Matrix-M1 Adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: MARPE Effect With/Without MOP in Non-growing Patients
Status: COMPLETED
Conditions: Maxillary Transverse Deficiency
Interventions: PROCEDURE: MARPE with MOP|PROCEDURE: MARPE without MOP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Massage Therapy and Occlusal Splint Therapy on the Electromyographic Activity and Mandibular Range of Motion in Individuals With Temporomandibular Disorder
Status: COMPLETED
Conditions: Temporomandibular Disorder
Interventions: OTHER: Massage|OTHER: Occlusal splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy With or Without Cyclophosphamide in Treating Patients Undergoing Chemotherapy and Radiation Therapy for Stage I or Stage II Pancreatic Cancer That Can Be Removed by Surgery
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: GVAX pancreatic cancer vaccine|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hysteroscopic Cryomyolysis for the Treatment of Submucosal Leiomyomata
Status: COMPLETED
Conditions: Uterine Fibroids|Leiomyoma|Menorrhagia
Interventions: PROCEDURE: Cryoablation for the treatment of uterine fibroids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MDD POC Study GSK372475 Subjects Depressive Disease
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: DRUG: GSK372475|DRUG: Paroxetine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HostDx Sepsis in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections: a Multicenter Pilot Study
Status: COMPLETED
Conditions: Respiratory Tract Infections|Urinary Tract Infections|Skin and Soft Tissue Infections|Intraabdominal Infections|Sepsis
Interventions: DIAGNOSTIC_TEST: HostDx Sepsis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Selonsertib in Adults With Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Placebo|DRUG: Selonsertib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of External Cues Versus Internal Cues Messaging on Heart Rate Variability and Affect
Status: COMPLETED
Conditions: Dietetics|Diet, Healthy|Nutrition Therapy|Affect|Autonomic Nervous System
Interventions: OTHER: Internal Cues Nutrition Messaging|OTHER: External Cues Nutrition Messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long Term Predictors of Graft Patency After Coronary Artery Bypass Graft Surgery (Multi-slice CT Coronary Angiography Study Validated by Coronary Angiography)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: multi-slice CT coronary angiography and coronary angiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy of PD-1 Antibody Sintilimab on Early-stage Multiple Primary Lung Cancer With Ground Glass Density.
Status: UNKNOWN
Conditions: Multiple Primary Lung Cancers
Interventions: DRUG: PD-1 antibody Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Calcipotriol Versus Narrowband Ultraviolet B in Treatment of Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: Calcipotriol|DEVICE: Narrow Band UVB|DIAGNOSTIC_TEST: vitamin D3 level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Neoadjuvant Temozolomide in Melanoma Patients With Palpable Stage III or IV Disease Undergoing Complete Surgical Resection
Status: COMPLETED
Conditions: Melanoma|Skin Cancer|Cancer
Interventions: DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PUMP (Providing the Underprivileged With Manual Pumps): An RCT
Status: COMPLETED
Conditions: Breastfeeding, Exclusive
Interventions: OTHER: Pump|OTHER: Book
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of SHR-1210 in Combination With Apatinib in Advanced Non-Small Cell Lung Cancer(NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: BIOLOGICAL: SHR-1210|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes and Safety: A Registry Study of Ilaris (Canakinumab) Patients
Status: COMPLETED
Conditions: Cryopyrin-associated Periodic Syndromes (CAPS)|Familial Cold Autoinflam Syn (FCAS)|Muckle-wells Syn (MWS)|Neonatal Onset Multisystem Inflam Disease (NOMID)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Human Acellular Vessel (HAV) With ePTFE Grafts as Conduits for Hemodialysis
Status: COMPLETED
Conditions: Renal Failure|End Stage Renal Disease|Hemodialysis|Vascular Access
Interventions: BIOLOGICAL: Human Acellular Vessel (HAV)|DEVICE: ePTFE graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Mastectomy Shoulder Pain And Lymphedema Responses To Ga-As Laser Versus Microcurrent Electrical Stimulation
Status: COMPLETED
Conditions: Post Mastectomy Lymphedema
Interventions: OTHER: Ga-As Laser|OTHER: Microcurrent Electrical Stimulation|OTHER: traditional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The ARCTIC Trial: Aerosolized Inhaled Adenosine Treatment in Patients With Acute Respiratory Distress Syndrome (ARDS) Caused by COVID-19
Status: WITHDRAWN
Conditions: Acute Respiratory Distress
Interventions: DRUG: Adenosine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Re-hospitalisation After Transcatheter Aortic Valve Implantation
Status: RECRUITING
Conditions: Aortic Valve Disease|Aortic Valve Stenosis
Interventions: BEHAVIORAL: Intensified follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Prognostic Study on Acupuncture Intervention for Traumatic Spinal Cord Injury
Status: COMPLETED
Conditions: Traumatic Spinal Cord Injury
Interventions: OTHER: conventional rehabilitation treatment|OTHER: Acupuncture treatment rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Compared With Hormone Therapy in Treating Patients With Recurrent, Stage III, or Stage IV Endometrial Cancer
Status: TERMINATED
Conditions: Endometrial Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: doxorubicin hydrochloride|DRUG: megestrol acetate|DRUG: paclitaxel|DRUG: tamoxifen citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparative Study on the Effects of Epidural Dexmedetomidine on Heart Rate Variability During General Anesthesia in Patients Undergoing Gastrectomy
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: preemptive dexmedetomidine epidural bolus injection(1.5 mcg/kg)|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7566802 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Locally Advanced Solid Tumors|Recurrent Solid Tumors|Metastatic Solid Tumors
Interventions: DRUG: RO7566802|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of Usual Care vs. Usual Care Plus Community Intervention to Manage Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|NIDDM|Non-insulin Dependent Diabetes Mellitus
Interventions: BEHAVIORAL: Home Visits and Lifestyle Education Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Neoadjuvant Bintrafusp Alfa in Patients With Resectable Biliary Tract Cancer
Status: TERMINATED
Conditions: Biliary Tract Cancer|Cholangiocarcinoma
Interventions: DRUG: Bintrafusp alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Ovarian, Fallopian Tube, or Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: MUC1-KLH conjugate vaccine|BIOLOGICAL: MUC1-KLH vaccine/QS21|BIOLOGICAL: QS21
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: 3 Month Safety Study of Dymista Nasal Spray and Fluticasone Propionate in Children 4-11 Years of Age With Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Dymista Nasal Spray|DRUG: Fluticasone propionate nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Earlier Intraocular Pressure Control After Ahmed Glaucoma Valve Implantation for Glaucoma
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: glaucoma medications (Timolol, Brimonidine, Dorzolamide, Brinzolamide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a 28-day Fermented Milk Product Consumption Twice Daily as Compared to a Non-fermented Milk Product on Intestinal Gas Production in Healthy Subjects High Dihydrogen Producers
Status: COMPLETED
Conditions: Excessive Intestinal Gas Production
Interventions: OTHER: Milk product fermented by lactic bacteria or not fermented
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral and Pharmacologic Treatment of Binge Eating and Obesity: Acute Treatment
Status: COMPLETED
Conditions: Binge-eating Disorder|Obesity
Interventions: DRUG: NB medication (Naltrexone Bupropion combination)|BEHAVIORAL: Behavioral Weight Loss (BWL) counseling|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b/2 Study of OMP-59R5 (Tarextumab) in Combination With Etoposide and Platinum Therapy
Status: TERMINATED
Conditions: Stage IV Small Cell Lung Cancer
Interventions: DRUG: OMP-59R5|DRUG: Etoposide|DRUG: Placebo|DRUG: Cisplatin or Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Bleeding and Aspirin Use in Spine Surgery
Status: WITHDRAWN
Conditions: Hemorrhage|Thrombosis
Interventions: DRUG: Acetylsalicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION