pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of Caregiver Connections Via Technology in Dementia
Status: RECRUITING
Conditions: Caregiver Stress|Dementia|Alzheimer Disease|Lewy Body Dementia|Parkinson Disease Dementia|Frontotemporal Dementia
Interventions: BEHAVIORAL: Algorithm|BEHAVIORAL: Random Match
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Biological Basis of Individual Variation in Social Cooperation
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Intranasal Oxytocin (OT) 24 IU|DRUG: Intranasal Vasopressin (AVP)|DRUG: Intranasal Placebo|DRUG: Intranasal Vasopressin (AVP) 40 IU|DRUG: Lorazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II Study of Everolimus in Children and Adolescents With Refractory or Relapsed Rhabdomyosarcoma and Other Soft Tissue Sarcomas
Status: UNKNOWN
Conditions: Refractory or Relapsed RMS and Soft Tissue Sarcomas
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemoembolisation With CPT11 Loaded DC Bead With Cetuximab and 5FU/LV in First Line in Patients With KRAS Wildtype mCRC
Status: WITHDRAWN
Conditions: Liver Metastases|Colorectal Cancer
Interventions: DEVICE: DC Bead™|DRUG: Cetuximab|DRUG: 5 FU|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Micronized Progesterone vs Gonadotropin-releasing Hormone (GnRH) Antagonist in Freeze-all IVF Cycles.
Status: COMPLETED
Conditions: Infertility|IVF|Preimplantation Diagnosis
Interventions: DRUG: GnRh antagonist|DRUG: Micronized progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab and Imatinib Mesylate in Advanced Cancer
Status: COMPLETED
Conditions: Advanced Malignant Solid Neoplasm|C-KIT Tyrosine Kinase Protein Overexpression|Clinical Stage IV Cutaneous Melanoma AJCC v8|Metastatic Gastrointestinal Stromal Tumor|Metastatic Malignant Solid Neoplasm|Metastatic Melanoma|Pathologic Stage IV Cutaneous Melanoma AJCC v8|Unresectable Melanoma|Unresectable Solid Neoplasm
Interventions: DRUG: Imatinib Mesylate|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of Telemedicine for Patient With Lower Extremity Wounds
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Peripheral Artery Disease|Peripheral Vascular Diseases|Diabetic Foot|Diabetic Foot Ulcer|Diabetic Foot Infection|Diabetic Peripheral Neuropathy
Interventions: OTHER: Telemedicine specialty consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Hyperbaric Oxygen Therapy in Addition to Standard Growth Factor Support for Hematopoietic Progenitor/Stem Cell Mobilization
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Hyperbaric Oxygen Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of Neuro Lung Protective Ventilation
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Brain Injury|Traumatic Brain Injury|Intracerebral Hemorrhage|Stroke|Cerebral Edema|Anoxic Brain Injury
Interventions: PROCEDURE: Lung Protective Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Effectiveness of a Nutritional Supplement With Natural Mastiha in Inflammatory Bowel Diseases.
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases
Interventions: DIETARY_SUPPLEMENT: Mastiha|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Computer Assisted Learning (CAL) Module Use for Re-training of Blood Pressure Measurements by Physical Therapy Students
Status: COMPLETED
Conditions: Blood Pressure
Interventions: OTHER: Computer Assisted Learning (CAL) Module
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: HAIC Combine With Lenvatinib and PD-1 Inhibitors for Advanced HCC With PVTT
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Portal Vein Thrombosis
Interventions: PROCEDURE: HAIC|DRUG: Lenvatinib 1|DRUG: PD-1 Inhibitors|DRUG: Lenvatinib 2|DRUG: PD-1 inhibitors 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reliability of Polish-Version Overactive Bladder Syndrom Scores (OABSS)
Status: COMPLETED
Conditions: Overactive Bladder|Urinary Incontinence
Interventions: DIAGNOSTIC_TEST: Urodynamic Study|DIAGNOSTIC_TEST: OABSS questionnaire fulfilment|DIAGNOSTIC_TEST: UDI-6 questionnaire fulfilment|DIAGNOSTIC_TEST: IIQ-7 questionnaire fulfilment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Presence of SARS-CoV-2 (COVID-19) in Semen: Impact on Fertility Preservation in Male Oncological Patients ?
Status: COMPLETED
Conditions: Sperm Preservation in Oncological Patients|Fertility|Cryopreservation
Interventions: DIAGNOSTIC_TEST: SARS-CoV-2 research in nasopharyngeal swab, sperm and serologics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Early Intervention for Youth at High Risk for Bipolar Disorder
Status: RECRUITING
Conditions: Bipolar Disorder
Interventions: BEHAVIORAL: Interpersonal and Social Rhythm Therapy (IPSRT)|BEHAVIORAL: The Healthy Lifestyle Behavior Intervention (HL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Incisors' Position Following Anterior Segment Retraction
Status: COMPLETED
Conditions: Bimaxillary Protrusion
Interventions: OTHER: Power chain used for anterior segment retraction|OTHER: T-loop fabricated to perform anterior segment retraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Renal Denervation in Patients With Uncontrolled Hypertension - SYMPLICITY HTN-4
Status: COMPLETED
Conditions: Hypertension|Vascular Diseases|Cardiovascular Diseases
Interventions: DEVICE: Renal Denervation using the Symplicity Renal Denervation System|OTHER: Sham Renal Denervation|DEVICE: Renal Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of TMC435 in Treatment-naive, Genotype 1, Hepatitis C-infected Patients
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Placebo|DRUG: TMC435|DRUG: Peginterferon alfa-2a (pegIFN alfa-2a)|DRUG: Ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TBS Treatment for Treatment-Resistant Depression
Status: COMPLETED
Conditions: Major Depressive Disorder|Unipolar Depression
Interventions: PROCEDURE: Theta Burst Stimulation|PROCEDURE: Sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Comparing Intravenous and Oral Diclofenac and Pharmacokinetics
Status: UNKNOWN
Conditions: Pain Management|Limb Injury
Interventions: DRUG: Diclofenac Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate Safety And Tolerability Of Single And Multiple Ascending Doses Of PF- 06260414 In Healthy Western And Japanese Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06260414|DRUG: Placebo|DRUG: PF-06260414|DRUG: Placebo|DRUG: PF-06260414|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Isa-KRd vs KRd in Newly Diagnosed Multiple Myeloma Patients Eligible for Autologous Stem Cell Transplantation (IsKia TRIAL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib Lenalidomide Dexamethasone|DRUG: Isatuximab Carfilzomib Lenalidomide Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ombitasvir/ Paritaprevir / Ritonavir Plus Ribavirin in Management HCV and End-stage Kidney Disease
Status: COMPLETED
Conditions: End-stage Renal Disease|HCV Coinfection
Interventions: DRUG: Ombitasvir / Paritaprevir / Ritonavir /Ribavirin Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study Investigating Mim8 in Adults and Adolescents With Haemophilia A With or Without Inhibitors
Status: RECRUITING
Conditions: Haemophilia A|Haemophilia A With Inhibitors
Interventions: DRUG: NNC0365-3769 (Mim8)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of a Novel Malathion Formulation in the Treatment of Head Lice
Status: COMPLETED
Conditions: Lice Infestations
Interventions: DRUG: MALG|DRUG: Ovide (malathion) lotion 0.05%|DRUG: Permethrin 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Peri-articular Injection of Bupivacaine With and Without Epinephrine
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Peri-articular injection of marcaine/epinephrine|PROCEDURE: Peri-articular injection of marcaine alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Evaluation of the Fetal Lung by Functional Magnetic Resonance Imaging - Blood Oxygenation Level Dependent (MRI-BOLD), in Congenital Diaphragmatic and Parietal Malformations
Status: WITHDRAWN
Conditions: Congenital Diaphragmatic Hernia|Omphalocele|Gastroschisis
Interventions: DIAGNOSTIC_TEST: Functional magnetic resonance imaging - Blood Oxygenation Level Dependent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Trial on Hepatitis B Vaccine Activated-Dendritic Cells Combined With Anti-HBV Drugs in CHB
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: BIOLOGICAL: HPDC-T cells & Entecavir|DRUG: Entecavir|DRUG: HPDC-T cells & IFN-a-2a|DRUG: IFN-a-2a|DRUG: HPDC-T cells & Telbivudine|DRUG: Telbivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Ventilation in Patients With Interstitial Lung Disease - a Feasibility Study
Status: UNKNOWN
Conditions: Noninvasive Ventilation|Lung Diseases, Interstitial
Interventions: OTHER: non-invasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tacrolimus/Everolimus vs. Tacrolimus/MMF in Pediatric Heart Transplant Recipients Using the MATE Score
Status: ACTIVE_NOT_RECRUITING
Conditions: Pediatric Heart Transplantation|Immunosuppression|Chronic Kidney Diseases|Cardiac Allograft Vasculopathy|Heart Transplant Failure and Rejection|Post-transplant Lymphoproliferative Disorder|Heart Transplant Infection
Interventions: DRUG: Everolimus|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of ABBV-932 in Healthy Adult Participants, Participants With Generalized Anxiety Disorder (GAD) and Participants With Bipolar Disorder (BPD)
Status: RECRUITING
Conditions: Healthy Volunteers|Generalized Anxiety Disorder (GAD)|Bipolar Disorder (BPD)
Interventions: DRUG: ABBV-932|DRUG: Placebo for ABBV-932
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Safety and Efficacy of EB-203 in Patients With Neovascular Age-related Macular Degeneration
Status: RECRUITING
Conditions: Neovascular Age-related Macular Degeneration (nAMD)
Interventions: DRUG: EB-203
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Long Term Extension of Study NC19453 Evaluating Safety and Efficacy of RO4607381
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DRUG: dalcetrapib (RO4607381)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Access to Control of Diseases for Women
Status: COMPLETED
Conditions: Cardio-vascular Disease|Stroke Cancer|Breast Cancer|Oral Cancer|Cervical Cancer
Interventions: DIAGNOSTIC_TEST: Evaluation of social, cultural and behavioral factors|DIAGNOSTIC_TEST: Evaluation of the feasibility and acceptability of delivery of early detections services
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effect of Scapular Stabilization Exercise Training on Posture and Pain in Fibromyalgia Patients
Status: COMPLETED
Conditions: Fibromyalgia|Exercise, Compulsive|Pain|Postural; Defect
Interventions: OTHER: exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Chloroquine and Coartem for Treatment of Symptomatic Children With Plasmodium Falciparum in Guinea Bissau
Status: COMPLETED
Conditions: Malaria, Falciparum
Interventions: DRUG: Chloroquine|DRUG: Artemether-lumefantrine (Coartem)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tipifarnib and Radiation Therapy in Treating Young Patients With Brainstem Glioma
Status: COMPLETED
Conditions: Untreated Childhood Brain Stem Glioma
Interventions: RADIATION: radiation therapy|DRUG: tipifarnib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot and Feasibility Trial of a Group Mindfulness and Self-compassion Intervention for Young People Diagnosed With IBD
Status: UNKNOWN
Conditions: Inflammatory Bowel Diseases
Interventions: BEHAVIORAL: Mindfulness-based stress reduction (MBSR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Local-anesthetic Wound Infusion for Neck Dissection
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Cancer
Interventions: DRUG: 0.5% Lidocaine Hydrochloride|DRUG: 0.9% Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Bevacizumab (Avastin) in Combination With Capecitabine (Xeloda) in Elderly Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Bevacizumab|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Everolimus and Imatinib Mesylate in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia Who Are Not in Complete Cytogenetic Remission After Previous Imatinib Mesylate
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: everolimus|DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED
Conditions: Malignant Neoplasms of Brain
Interventions: BIOLOGICAL: tetanus toxoid|BIOLOGICAL: therapeutic autologous dendritic cells|BIOLOGICAL: therapeutic autologous lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate JCXH-211 as Monotherapy in Patients With Malignant Solid Tumors
Status: RECRUITING
Conditions: Cutaneous Tumor|Malignant Solid Tumor
Interventions: DRUG: JCXH-211 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Highest Dose of Uproleselan in Combination With Fludarabine and Cytarabine for Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Mixed Phenotype Acute Leukemia Relapsed or Refractory and That Expresses E-selectin Ligand on the Cell Membrane
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia Post Cytotoxic Therapy|Down Syndrome|Myelodysplastic Syndrome Post Cytotoxic Therapy|Recurrent Acute Myeloid Leukemia|Recurrent Mixed Phenotype Acute Leukemia|Recurrent Myelodysplastic Syndrome|Refractory Acute Myeloid Leukemia|Refractory Mixed Phenotype Acute Leukemia|Refractory Myelodysplastic Syndrome
Interventions: DRUG: Cytarabine|DRUG: Fludarabine|DRUG: Leucovorin|DRUG: Triple Intrathecal Chemotherapy|DRUG: Uproleselan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining the Role of Transrectal High Intensity Focused Ultrasound (HIFU) in Rectal Pelvic Cancer
Status: WITHDRAWN
Conditions: Rectal Cancer|Ovarian Cancer|Endometrial Cancer|Vaginal Cancer|Cervical Cancer
Interventions: DEVICE: Sonablate 500 (High Intensity Focused Ultrasound (HIFU))
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Development of an Intelligent POWER Rehabilitation Cluster Machine and Its Clinical Testing and Assessment
Status: UNKNOWN
Conditions: Frailty Syndrome|Intelligent POWER Rehabilitation Cluster Machine
Interventions: DEVICE: Intelligent POWER Rehabilitation Cluster Machine|OTHER: general physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extended Pouch Gastric Bypass vs One-anastomosis Gastric Bypass in Patients With BMI≥45
Status: NOT_YET_RECRUITING
Conditions: Bariatric Surgery Candidate
Interventions: PROCEDURE: Randomizing for EPGB procedure|PROCEDURE: Randomizing for OAGB procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: LapLAND Laparoscopic Lavage for Acute Non-Faeculant Diverticulitis
Status: UNKNOWN
Conditions: Diverticulitis
Interventions: PROCEDURE: Laparoscopic Washout|PROCEDURE: Hartmann's Procedure/ Primary Resection and Anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Gemtuzumab Ozogamycin for Patients Presenting an Acute Myeloid Leukemia (AML) With Intermediate Risk
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: gemtuzumab ozogamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Methotrexate Microemulsion in the Treatment of Plaque Psoriasis
Status: UNKNOWN
Conditions: Psoriasis|Methotrexate
Interventions: DRUG: topical methotrexate micoemulsion|DEVICE: Excimer light|DEVICE: Narrow band ultraviolet B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Treatment of Drug Abuse in Severe and Persistent Mental Illness (SPMI) Patients
Status: COMPLETED
Conditions: Schizophrenia|Mood Disorders|Substance Dependence
Interventions: BEHAVIORAL: Behavioral Treatment for Substance Abuse in SPMI (BTSAS)|BEHAVIORAL: Supportive Treatment in Addiction Recovery (STAR)|BEHAVIORAL: Critical Time Intervention (CTI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Ilioinguinal-iliohypogastric Block for Inguinal Hernia Repair
Status: UNKNOWN
Conditions: Inguinal Hernia
Interventions: DRUG: bupivacaine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Temporary Placement of a Phrenic Nerve Stimulator for Diaphragm Pacing
Status: COMPLETED
Conditions: Ventilator Induced Diaphragm Dysfunction
Interventions: DEVICE: Diaphragmatic Pacing Therapy DPTS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Breaking the Cycle IV: Military PTSD (MPTSD) Treatment Study
Status: COMPLETED
Conditions: PTSD|Anger|Aggression
Interventions: BEHAVIORAL: TARGET (Trauma Affect Regulation)|BEHAVIORAL: Prolonged Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of High-flow Nasal Oxygen Therapy and Facial Mask Ventilation on the Increase of the Oxygen Reserve Index During Anesthetic Induction
Status: COMPLETED
Conditions: Adult Patients 20 Years of Age or Older Who Are Planning to Undergo Surgery Under General Anesthesia
Interventions: PROCEDURE: High-flow nasal oxygen technique|PROCEDURE: Mask ventilation technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Delphinus SoftVue Prospective Case Collection - ARM 1
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DEVICE: Routine Full-Field Digital Mammography|DEVICE: Routine Digital Breast Tomosynthesis|DEVICE: Automated Whole Breast Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Albuterol Versus Xopenex in Treatment of Acute Asthma in the Emergency Department (ED)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: xopenex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of a 3D Spacer Mattress for Pressure Relieving in Cardiac Surgery and Evaluation of Its Efficacy
Status: COMPLETED
Conditions: Pressure Ulcer|Cardiac Surgery
Interventions: COMBINATION_PRODUCT: 3D spacer Fabric Based Mattress
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Investigate Dose-related Efficacy of LAS41004 in the Treatment of Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: LAS 41004|DRUG: LAS 41004|DRUG: LAS 41004|DRUG: LAS 41004|DRUG: LAS 41004|DRUG: LAS 41004 dosage 6|DRUG: Placebo|DRUG: Reference
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Parotid-gland Stem-cell Sparing Intensity-modulated Radiotherapy
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: RADIATION: Intensity-modulated Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cohort/Ethics Study of Patients With Severe Alcoholic Hepatitis Undergoing Early Liver Transplantation
Status: ENROLLING_BY_INVITATION
Conditions: Liver Diseases, Alcoholic|Alcohol-Related Disorders|Transplant; Failure, Liver|Transplant; Complication, Rejection|Liver Diseases|Hepatitis, Alcoholic|Alcohol-Induced Disorders
Interventions: PROCEDURE: liver transplant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cannabidiol (CBD) in Adults With ASD
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DRUG: Cannabidiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Early Childhood Caries Using Silver Diammine Fluoride and Sodium Fluoride Tricalciumphosphate and the Effects on Oral Health Related Quality of Life
Status: ENROLLING_BY_INVITATION
Conditions: Early Childhood Caries|Dental Caries in Children|Dental Caries Extending Into Dentin|Dental Caries|Behavior, Child|Quality of Life
Interventions: DRUG: Topical application of 38% Silver Diammine Fluoride Solution|DRUG: Topical application of 5% Sodium Fluoride with functional Tricalcium phosphate Varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Body Surface Gastric Mapping to Evaluate Patients With Upper Gastrointestinal Symptoms and Controls
Status: ENROLLING_BY_INVITATION
Conditions: Motility Disorder|Gastroparesis|Functional Dyspepsia|Cyclical Vomiting|Cannabinoid Hyperemesis Syndrome|Diabetic Gastroparesis
Interventions: DEVICE: Gastric Alimetry System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of PEG-rIL-29 (or PEG-IFN Lambda) in Subjects With Chronic Hepatitis C Virus Infection
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: PEGylated recombinant interleukin 29 (PEG-rIL-29)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Lipodystrophy on the Inflammatory State of Non-diabetic Dunnigan Reunion Island Subjects
Status: RECRUITING
Conditions: Lipodystrophy|Dunnigan Syndrome
Interventions: BIOLOGICAL: Bood and urine sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of MEK162 for Children With Low-Grade Gliomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Low-Grade Gliomas|Malignant Neoplasms, Brain|Soft Tissue Neoplasms
Interventions: DRUG: MEK162
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Interferon Alfa in Treating Patients With Low-Grade Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: recombinant interferon alfa|DRUG: chlorambucil|DRUG: dexamethasone|DRUG: idarubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation to Reduce Chronic Pelvic Pain in Endometriosis
Status: UNKNOWN
Conditions: Endometriosis
Interventions: DEVICE: tDCS : Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post IVIG Medication in Children With Immune Thrombocytopenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Acetaminophen and Diphenhydramine Only Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Belimumab in Patients With Active Lupus Nephritis
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: BIOLOGICAL: Placebo plus standard therapy|BIOLOGICAL: Belimumab 10 mg/kg plus standard therapy|DRUG: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Accuracy of the Neurological Prognosis at 6 Months of Traumatic Brain Injury Between Junior and Senior Doctors
Status: COMPLETED
Conditions: Prognosis of Neurological Outcome at 6 Months in Patients Undergoing Traumatic Brain Injury
Interventions: OTHER: Predict the outcome of the Glasgow Outcome Scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PROPEL - A Prospective Observational Patient Registry to Evaluate ENPP1 and ABCC6 Deficiency
Status: RECRUITING
Conditions: Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 Deficiency|ATP-Binding Cassette Subfamily C Member 6 Deficiency
Interventions: OTHER: No Intervention for this observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Silver Nitrate Application and Topical Corticosteroids for Hypergranulation Tissue
Status: UNKNOWN
Conditions: Hypergranulation Tissue; Gastrostomy Tube Site
Interventions: DRUG: Silver Nitrate|DRUG: Triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ecopipam Tablets to Study Tourette Syndrome in Children and Adolescents - Open Label Extension
Status: COMPLETED
Conditions: Tourette Syndrome in Children|Tourette Syndrome in Adolescence
Interventions: DRUG: Ecopipam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ML29255 Neoadjuvant Vemurafenib and Cobimetinib Melanoma
Status: WITHDRAWN
Conditions: Stage IIIB-C Melanoma
Interventions: DRUG: Vemurafenib and Cobimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Insulin Resistance in Non-alcoholic Fatty Liver Disease
Status: TERMINATED
Conditions: Fatty Liver
Interventions: DRUG: fenofibrate|DRUG: pioglitazone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Lucentis® Compared to Lucentis® Monotherapy
Status: TERMINATED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: E10030|DRUG: ranibizumab|DRUG: E10030 sham intravitreal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of 90Y-hMN14 to Treat Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: DRUG: hMN14 (labetuzumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Operative Atrial Fibrillation After Surgical Aortic Valve Replacement and the Influence of Statins
Status: RECRUITING
Conditions: Postoperative Atrial Fibrillation
Interventions: DRUG: Discontinuance of treatment with statins 7 to 14 days prior to surgery until 30 days postoperative|DRUG: No-intervention.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transurethral Versus Percutaneous Endoscopic Management of Bladder Stones in Boys
Status: COMPLETED
Conditions: Pediatric Bladder Stones
Interventions: PROCEDURE: Transurethral extraction of bladder stone(s)|PROCEDURE: percutaneous extraction of bladder stone(s)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Use of RIA to Harvest Bone Graft for Treatment of Non-unions and Fractures
Status: COMPLETED
Conditions: Orthopaedic Trauma Fractures and Non-unions
Interventions: DEVICE: Reamer-Irrigator-Aspirator (RIA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determining Whether There is a Change in Time Taken to Return to Homeostatic Temperature With Repeated Exposure to a Cold Stressor
Status: NOT_YET_RECRUITING
Conditions: Needle Phobia|Needle Fear|Injection Fear
Interventions: OTHER: Metal block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Endometrial Receptivity in Patients With Recurrent Implantation Failure as a Preparatory Step for PET
Status: UNKNOWN
Conditions: RIF , Endometrial Receptivity
Interventions: DIAGNOSTIC_TEST: endometrial biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INcobotulinumtoxina in ChIldren Upper and Lower Limb sPasticITy (INCIPIT)
Status: NOT_YET_RECRUITING
Conditions: Spastic Cerebral Palsy
Interventions: DRUG: IncobotulinumtoxinA 100 UNT [Xeomin]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Scar in the Control Excess of Mobility Induced by Annulus Removal on Inserting a Lumbar Disc Prosthesis
Status: RECRUITING
Conditions: Lumbar Disc Disease
Interventions: PROCEDURE: Anterior lumbar disc annulus removal versus replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intermittent Treatment With Sulfadoxine-pyrimethamine for Malaria Control in Infants
Status: COMPLETED
Conditions: Malaria|Anemia
Interventions: DRUG: Sulfadoxine (12.5 mg)/Pyrimethamine (250 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy and Surgery With or Without G-CSF in Treating Patients With Osteosarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: doxorubicin hydrochloride|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Expiratory Muscle Training in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DEVICE: EMST - Active Treatment|DEVICE: sham EMST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Treatment With 177Lu-DOTA0-Tyr3-Octreotate to Octreotide LAR in Patients With Inoperable, Progressive, Somatostatin Receptor Positive Midgut Carcinoid Tumours
Status: COMPLETED
Conditions: Carcinoid Tumor of the Small Bowel|Neuroendocrine Tumour
Interventions: DRUG: Octreotide LAR|DRUG: 177Lu-DOTA0-Tyr3-Octreotate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Are the Stone Density and Location Useful Parameters for Small Kidney Stones?
Status: COMPLETED
Conditions: Kidney Calculi|Kidney Stone
Interventions: PROCEDURE: Mini percutaneous nephrolithotomy|PROCEDURE: Retrograde intrarenal surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect and Underlying Immunological Mechanisms of Sublingual Immunotherapy in Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: sublingual immunotherapy drops|DRUG: Placebo drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An E-health Intervention for Patients With Peripheral Artery Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Intermittent Claudication
Interventions: DEVICE: A PAD-specific smartphone application (e-intervention) developed for patients with Peripheral Artery Disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NBI for Early Diagnosis of OPMD/OSCC
Status: NOT_YET_RECRUITING
Conditions: Oral Squamous Cell Carcinoma|Oral Potentially Malignant Disorder
Interventions: OTHER: Biopsy for diagnostical purposes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Comparison Study of the Bioavailability of a Capsule Formulation of LGD-6972 to an Oral Solution Formulation
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus (T2DM)
Interventions: DRUG: LGD-6972 Solution|DRUG: LGD-6972 Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Chemotherapy Before and After Surgery Versus After Surgery Alone for the Treatment of Gallbladder Cancer
Status: RECRUITING
Conditions: Stage II Gallbladder Cancer AJCC v8|Stage IIA Gallbladder Cancer AJCC v8|Stage IIB Gallbladder Cancer AJCC v8|Stage III Gallbladder Cancer AJCC v8|Stage IIIA Gallbladder Cancer AJCC v8|Stage IIIB Gallbladder Cancer AJCC v8
Interventions: DRUG: Cisplatin|DRUG: Gemcitabine Hydrochloride|PROCEDURE: Lymphadenectomy|PROCEDURE: Partial Hepatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of HT Concomitant With RT vs RT Alone in Patients With a Detectable PSA After Prostatectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Adenocarcinoma of Prostate
Interventions: DRUG: Degarelix|RADIATION: Pelvic Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TMC114-C226: An Early Access Program to Evaluate the Long-term Safety and Tolerability of TMC114 Combined With a Low Dose of Ritonavir (TMC114/r) With Other Antiretrovirals, for HIV-1 Infected Patients Who Have Failed Multiple Antiretroviral Regimens.
Status: APPROVED_FOR_MARKETING
Conditions: HIV Infections
Interventions: DRUG: TMC-114
Study Type: EXPANDED_ACCESS
Clinical trial: Treatment With Risperidone Long Acting Injectable (RLAI) in an Early Phase of Psychosis
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorders|Schizoaffective Disorder
Interventions: DRUG: risperidone long acting injectable
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of Repeat Doses of Inhaled Nemiralisib in Patients With APDS/PASLI
Status: COMPLETED
Conditions: Activated PI3K-delta Syndrome
Interventions: DRUG: Nemiralisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serum and Cellular Biomarkers for Aortic Valve Stenosis
Status: RECRUITING
Conditions: Calcific Aortic Valve Disease|Aortic Valve Stenosis|Aortic Valve, Calcification of
Interventions: DIAGNOSTIC_TEST: Echocardiography|DIAGNOSTIC_TEST: Computerized Tomography Aortic Valve Calcium Score|OTHER: Untargeted LC/MS and LC-MS/MS|OTHER: Targeted LC/MS and LC-MS/MS|DIAGNOSTIC_TEST: multiplex ELISA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of rhuMAb VEGF (Bevacizumab) in Combination With Chemotherapy in Patients With Previously Treated Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: rhuMAb VEGF (Bevacizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Plant Rich Diet on in People With Type 2 Diabetes and Obesity
Status: WITHDRAWN
Conditions: Type 2 Diabetes Mellitus in Obese
Interventions: OTHER: NDPR diet|OTHER: USDA healthy eating diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCTrial to Test Low Intensity Shockwave Treatment in Patients With Mild/Moderate Erectile Dysfunction
Status: UNKNOWN
Conditions: Erectile Dysfunction|Endothelial Dysfunction
Interventions: DEVICE: Treatment|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics in Special Needs Patients at High Risk for Tooth Decay: a Randomized Controlled Trial.
Status: NOT_YET_RECRUITING
Conditions: Tooth Decay|Intellectual Disability|Caries,Dental
Interventions: OTHER: Test Group|OTHER: Positive Control|OTHER: Negative Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective, Randomized Study for Predicting Human Cytomegalovirus (hCMV) Infection Based on Baseline hCMV Specific T-cell Response in Kidney Transplant
Status: COMPLETED
Conditions: CMV Infection|Kidney Transplantation
Interventions: OTHER: BIOMARKER- elispot test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial To Evaluate ANT-1207 In Participants With Primary Axillary Hyperhidrosis
Status: COMPLETED
Conditions: Hyperhidrosis
Interventions: BIOLOGICAL: Vehicle|BIOLOGICAL: ANT-1207
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of Dabigatran and Atorvastatin in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dabigatran|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Travel Direction, Body Position and Technique on the Ease of Getting an Occupied Wheelchair Over a Soft Surface
Status: COMPLETED
Conditions: Wheelchairs
Interventions: OTHER: Wheelchair forward direction|OTHER: Wheelchair backward direction|OTHER: Upright technique|OTHER: Wheelie technique|OTHER: Wheelchair occupant upright body position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Maternal and Perinatal Outcome in Women With History of Premature Labor in Previous Pregnancy
Status: COMPLETED
Conditions: Pregnancy|Vulvovaginitis|Uterine Cervicitis|Pregnancy Outcome
Interventions: OTHER: Active search of lower genital tract infections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Steps for PRosTAte Cancer Health and Survival (SPaRTACuS): Pilot Study of a Walking Intervention to Improve Health and Quality of Life in Prostate Cancer Patients
Status: COMPLETED
Conditions: Prostatic Neoplasm
Interventions: BEHAVIORAL: Walking Intervention|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Maintenance Apatinib Combined With Pemetrexed in Advanced Non-squamous Non-small Cell Lung Cancer Patients
Status: WITHDRAWN
Conditions: Advanced Non-squamous Non-small-cell Lung Cancer
Interventions: DRUG: Apatinib|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory P2 Trial to Evaluate Efficacy and Safety of Clotinab® (Abciximab) in Acute MI Patients
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: BIOLOGICAL: Abciximab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Vaccine Therapy With or Without Interleukin-12 in Treating Patients With Stage III or Stage IV Melanoma
Status: COMPLETED
Conditions: Intraocular Melanoma|Melanoma (Skin)
Interventions: BIOLOGICAL: gp100 antigen|BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: recombinant interleukin-12|BIOLOGICAL: tyrosinase peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study on Effect of Intestinal Microbiota Transplantation in Chronic Hepatitis B
Status: UNKNOWN
Conditions: Chronic Hepatitis b
Interventions: OTHER: intestinal microbiota transplant|DRUG: Antiviral Agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT