pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Differentiated Thyroid Gland Carcinoma|Advanced Head and Neck Carcinoma|Advanced Hepatocellular Carcinoma|Advanced Kaposi Sarcoma|Advanced Lung Non-Small Cell Carcinoma|Advanced Lung Small Cell Carcinoma|Advanced Malignant Solid Neoplasm|Advanced Melanoma|Advanced Ovarian Carcinoma|Advanced Prostate Carcinoma|Advanced Renal Cell Carcinoma|Advanced Thyroid Gland Medullary Carcinoma|Advanced Triple-Negative Breast Carcinoma|Advanced Urothelial Carcinoma|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8|Castration-Resistant Prostate Carcinoma|Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|HIV Infection|Metastatic Differentiated Thyroid Gland Carcinoma|Metastatic Head and Neck Carcinoma|Metastatic Hepatocellular Carcinoma|Metastatic Kaposi Sarcoma|Metastatic Lung Non-Small Cell Carcinoma|Metastatic Lung Small Cell Carcinoma|Metastatic Malignant Solid Neoplasm|Metastatic Melanoma|Metastatic Ovarian Carcinoma|Metastatic Prostate Carcinoma|Metastatic Renal Cell Carcinoma|Metastatic Thyroid Gland Medullary Carcinoma|Metastatic Triple-Negative Breast Carcinoma|Metastatic Urothelial Carcinoma|Recurrent Differentiated Thyroid Gland Carcinoma|Recurrent Head and Neck Carcinoma|Recurrent Hepatocellular Carcinoma|Recurrent Kaposi Sarcoma|Recurrent Lung Non-Small Cell Carcinoma|Recurrent Lung Small Cell Carcinoma|Recurrent Malignant Solid Neoplasm|Recurrent Melanoma|Recurrent Ovarian Carcinoma|Recurrent Prostate Carcinoma|Recurrent Renal Cell Carcinoma|Recurrent Thyroid Gland Medullary Carcinoma|Recurrent Triple-Negative Breast Carcinoma|Recurrent Urothelial Carcinoma|Refractory Differentiated Thyroid Gland Carcinoma|Stage III Differentiated Thyroid Gland Carcinoma AJCC v8|Stage III Hepatocellular Carcinoma AJCC v8|Stage III Lung Cancer AJCC v8|Stage III Ovarian Cancer AJCC v8|Stage III Prostate Cancer AJCC v8|Stage III Renal Cell Cancer AJCC v8|Stage III Thyroid Gland Medullary Carcinoma AJCC v8|Stage IV Differentiated Thyroid Gland Carcinoma AJCC v8|Stage IV Hepatocellular Carcinoma AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IV Ovarian Cancer AJCC v8|Stage IV Prostate Cancer AJCC v8|Stage IV Renal Cell Cancer AJCC v8|Stage IV Thyroid Gland Medullary Carcinoma AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Cabozantinib S-malate|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesic Effect of Infraspinatus-teres Minor Inter-fascial Block in Patients Undergoing Shoulder Surgery
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: PROCEDURE: Infraspinatus-teres minor interfascial block|PROCEDURE: interscalene block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Infusion of Allogeneic CD19-Specific T Cells From Peripheral Blood
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: PROCEDURE: HSCT|GENETIC: DLI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety, Tolerability and Pharmacokinetics of of AZD6553 in Healthy Volunteers and Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: AZD6553|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Assessing AR-13503 Implant in Subjects With nAMD or DME
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration|Diabetic Macular Edema
Interventions: DRUG: AR-13503 Implant 10.6 Dose|DRUG: AR-13503 Implant 21.2 Dose|DRUG: AR-13503 42.4 Dose|DRUG: AR-13503 63.6 Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Proton Radiation for the Treatment of Locally Advanced Lung Cancer
Status: TERMINATED
Conditions: Locally Advanced Non-Small Cell Lung Cancer
Interventions: RADIATION: Proton Radiation Therapy|DRUG: Taxol|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-Dose Study of the Pharmacokinetics of Vibegron (MK-4618) in Adults With Hepatic Insufficiency (MK-4618-013)
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Vibegron
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trans-abdominal Fetal Pulse Oximetry
Status: TERMINATED
Conditions: Fetal Hypoxia|Fetal Distress|Fetal Acidemia|Fetal or Neonatal Effect of Complication of Labor
Interventions: DEVICE: Dual fetal oxygen sensors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Modified Duct-to-mucosa Pancreaticojejunostomy After Pancreaticoduodenectomy
Status: UNKNOWN
Conditions: Pancreatic Fistula
Interventions: PROCEDURE: Modified one-layer duct-to-mucosa Pancreaticojejunostomy|PROCEDURE: Invagination pancreaticojejunostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vaccination of High Risk Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer|Breast Neoplasms
Interventions: BIOLOGICAL: P10s-PADRE/ MONTANIDE™ ISA 51 VG|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Molnupiravir (MK-4482) in Hospitalized Adult Participants With COVID-19 (MK-4482-001)
Status: TERMINATED
Conditions: Coronavirus Disease (COVID-19)
Interventions: DRUG: Molnupiravir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of the Effects of Omega-3-acid Ethyl Esters on the Lipid and Lipoprotein Profile in the Blood
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: TAK-085|OTHER: Not treated with omega-3-acid ethyl esters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Safety and Pharmacokinetic Study of AG-881 in Healthy Male Participants Following Administration of a Single Oral Dose of [14C] AG-881 and Concomitant Intravenous Microdose of [13C315N3] AG-881
Status: COMPLETED
Conditions: Healthy Male Participants
Interventions: DRUG: AG-881|DRUG: [13C315N3]AG-881
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Docosahexaenoic Acid (DHA) To Prevent Development of Cognitive Dysfunction Due to Chemotherapy
Status: COMPLETED
Conditions: Cognitive Dysfunction
Interventions: DRUG: DHA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Effectiveness of Risperdal® Consta® Compared to Abilify® Over a Two-year Period in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorders
Interventions: DRUG: Abilify|DRUG: Risperidal Consta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of a H5N1 Influenza Vaccine (Vero Cell-Derived, Whole Virus) in Healthy Infants, Children and Adolescents
Status: COMPLETED
Conditions: Influenza, Avian
Interventions: BIOLOGICAL: H5N1 Influenza Vaccine (Whole Virion, Vero Cell-Derived, Inactivated), non-adjuvanted formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study of a Topical Gentamicin-Collagen Sponge Along With Systemic Antibiotic in Infected Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Foot Ulcer, Diabetic|Infection
Interventions: DRUG: Gentamicin collagen sponge|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A New Marker for Early Diagnosis of Pneumoperitoneum-Related Acute Kidney Injury: Insulin-Like Growth Factor-1 (IGF-1)
Status: COMPLETED
Conditions: Acute Kidney Injury (Nontraumatic)|Pneumoperitoneum
Interventions: DIAGNOSTIC_TEST: IGF-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PRORADIUM: Prospective Multi-centre Study of Prognostic Factors in mCRPC Patients Treated With Radium-223.
Status: UNKNOWN
Conditions: Advanced Prostate Cancer|Castration Resistant|Radium 223
Interventions: DRUG: Radium 223 55mBq/Kg every 4 weeks intravenously
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase III Clinical Trial to Assess Safety and Immunogenicity of a COVID-19 Vaccine Booster Dose in Immunosupressed Adults.
Status: COMPLETED
Conditions: SARS CoV 2 Infection
Interventions: BIOLOGICAL: PHH1-V
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Recombinant Influenza Vaccine Versus Standard Egg-Based Inactivated Influenza Vaccine in Adults 18-64 Years
Status: TERMINATED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: Fluzone Quadrivalent|BIOLOGICAL: Flublok Quadrivalent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Digital Single Session Intervention for Youth Mental Health
Status: RECRUITING
Conditions: Anxiety|Depression|Conduct Disorder|Stress
Interventions: BEHAVIORAL: Practicing the Opposite (PTO)|OTHER: Usual Clinical Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Micropulse Laser Trabeculoplasty as Adjunctive Treatment in Patients With Pseudoexfoliation Glaucoma
Status: COMPLETED
Conditions: Pseudoexfoliation Glaucoma|Primary Open-angle Glaucoma
Interventions: PROCEDURE: Micropulse laser trabeculoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Addition of Metformin to SGLT2 In Diabetic Patients With Heart Failure With Preserved Ejection Fraction
Status: NOT_YET_RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction|Diabete Type 2
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 11C Methionine PET for the Detection of Hyperfunctional Parathyroid Tissues
Status: UNKNOWN
Conditions: Primary Hyperparathyroidism
Interventions: RADIATION: 11C-Methionine PET/CT scanning|RADIATION: 18F-FDG PET/CT scanning|RADIATION: SPECT-CT scanning
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study to Assess Preliminary Efficacy, Safety and Tolerability of HH-120 Nasal Spray in COVID-19 Patients
Status: COMPLETED
Conditions: Coronavirus Disease 2019(COVID-19)
Interventions: BIOLOGICAL: HH-120 Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth of Healthy Term Infants Fed Formula Containing DHA-B
Status: COMPLETED
Conditions: Growth|Tolerance|Infant Development
Interventions: OTHER: infant formula with DHASCO|OTHER: infant formula with DHASCO-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Breath-Enhanced and T-Piece Nebulizers in Children With Acute Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: T-Piece Nebulizer|DEVICE: Breath-Enhanced Nebulizer|DRUG: Albuterol|PROCEDURE: Pre-Treatment Spirometry Measurement|PROCEDURE: Post-Treatment Spirometry Measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Non-invasive Neuromodulation in Patients With Long-COVID
Status: RECRUITING
Conditions: Long-COVID|Post-acute COVID-19 Syndrome
Interventions: DEVICE: Non-invasive neuromodulation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Concurrent Chemo-radiotherapy Combined With Recombinant Human Endostatin for Local Advanced Non-small Cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: RADIATION: radiotherapy combined with EP|DRUG: radiotherapy / EP combined with recombinant human endostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib on Metformin
Status: COMPLETED
Conditions: Drug-drug Interaction
Interventions: DRUG: Tucatinib|DRUG: Metformin|DRUG: Iohexol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency of PRGF-Endoret in Combination With a Bone Graft in Lateral Sinus Floor Elevation
Status: COMPLETED
Conditions: Sinus Floor Augmentation
Interventions: DEVICE: Bio-Oss|DEVICE: calcium phosphate ceramic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First-in-human Study to Learn How Safe the Study Drug BAY2965501 is, Find the Best Dose (Single Drug & Combination), How it Affects the Body, What Maximum Amount Can be Given, How it Moves Into, Through and Out of the Body, How it Acts on Different Tumors in Participants With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: BAY2965501|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Second Study of the Effect of Teriparatide on Hip Fracture Healing
Status: COMPLETED
Conditions: Femur Neck Fracture
Interventions: DRUG: Teriparatide|DRUG: Placebo|DIETARY_SUPPLEMENT: Calcium supplementation|DIETARY_SUPPLEMENT: Vitamin D supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Association of Mean Platelet Volume and Cardiovascular Disease in Children With End Stage Renal Disease.
Status: COMPLETED
Conditions: Cardiovascular Diseases|Carotid Intimal Media Thickness|Left Ventricular Hypertrophy|Mean Platelet Volume|End Stage Renal Disease|Hemodialysis Complication|Peritoneal Dialysis Complication|Children
Interventions: DIAGNOSTIC_TEST: Imaging|OTHER: Blood sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Platelet Rich Plasma Combined With Platelet Rich Fibrin in Management of Temporomandibular Joint Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis
Interventions: COMBINATION_PRODUCT: Prp with prf or prp or prf
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Digital Health Psychosocial Intervention for Adolescent Spine Surgery Preparation and Recovery
Status: ACTIVE_NOT_RECRUITING
Conditions: Juvenile; Scoliosis|Scoliosis Idiopathic|Scoliosis; Adolescence|Scoliosis;Congenital|Kyphosis|Spondylolisthesis
Interventions: BEHAVIORAL: CBT (SurgeryPal)|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy of Percutaneous Cryoablation for Renal Tumours < 4cm in Patients Who Are Not Candidates for Partial Nephrectomy
Status: COMPLETED
Conditions: Renal Tumors Less Than 4 cm
Interventions: DEVICE: Galil Medical patented 17G Cryoablation Needles
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Pharmacokinetic Behavior of Antiretroviral Drugs in Patients Infected by HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nevirapine|DRUG: Efavirenz|DRUG: Indinavir/ritonavir|DRUG: Nelfinavir|DRUG: Saquinavir/ritonavir|DRUG: Lopinavir/ritonavir|DRUG: Atazanavir|DRUG: Atazanavir/ritonavir|DRUG: Fos-amprenavir/ritonavir|DRUG: Tipranavir/ ritonavir|DRUG: Darunavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monitoring of Mobility of Parkinson's Patients for Therapeutic Purposes - Clinical Trial
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: Parkinson Holter|DIAGNOSTIC_TEST: Motor fluctuations diary|OTHER: Traditional clinical practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Safety and Immunogenicity of Three Consistency Lots and a High-Dose Lot of rVSV-ZEBOV-GP (V920 Ebola Vaccine) in Healthy Adults (V920-012)
Status: COMPLETED
Conditions: Prevention of Ebola Infection
Interventions: BIOLOGICAL: V920 Consistency Lot A|BIOLOGICAL: V920 Consistency Lot B|BIOLOGICAL: V920 Consistency Lot C|BIOLOGICAL: V920 High-dose Lot|BIOLOGICAL: Placebo to V920
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Kimchi Intake on Body Fat in Overweight Subjects
Status: NOT_YET_RECRUITING
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Kimchi|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lesinurad Monotherapy in Gout Subjects Intolerant to Xanthine Oxidase Inhibitors
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: lesinurad|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy or Intensity-Modulated Radiation Therapy in Treating Patients With Stage IIA-B Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage II Prostate Adenocarcinoma
Interventions: RADIATION: Intensity-Modulated Radiation Therapy (IMRT)|RADIATION: Stereotactic Body Radiation Therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Inflammatory Effects of Mango Polyphenolics in Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Intestinal Diseases|Ulcerative Colitis|Crohn Disease
Interventions: DRUG: Mango polyphenolics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Licorice and Hydrochlorothiazide on Plasma Potassium
Status: COMPLETED
Conditions: Hypokalemia
Interventions: DRUG: Hydrochlorothiazide|DIETARY_SUPPLEMENT: Licorice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Immunogenicity and Safety of a Booster Dose of DTaP-IPV-HB-PRP~T Combined Vaccine in Healthy Turkish Infants
Status: COMPLETED
Conditions: Diphtheria|Polio|Pertussis|Hepatitis B
Interventions: BIOLOGICAL: DTaP-IPV-HB-PRP~T vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Validation of Cognitive Screenings for the Hearing Impaired
Status: TERMINATED
Conditions: Dementia|Hearing Loss|Auditory Processing Disorder
Interventions: DIAGNOSTIC_TEST: Cognitive tests and hearing tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Pregnant-controlled Sacral Massage on Mothers' Labor Pain, Perception, Process and Midwives' Satisfaction
Status: NOT_YET_RECRUITING
Conditions: Labor Pain|Labor
Interventions: OTHER: massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of CC-90002 in Subjects With Acute Myeloid Leukemia (AML) and High-risk Myelodysplastic Syndrome (MDS)
Status: TERMINATED
Conditions: Leukemia, Myeloid, Acute|Myelodysplastic Syndromes
Interventions: DRUG: CC-90002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy Plus Carboplatin and Lobradimil in Treating Children With Newly Diagnosed Brain Stem Gliomas
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: carboplatin|DRUG: cereport|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Maple Syrup on Gut Microbiota Diversity and Metabolic Syndrome
Status: COMPLETED
Conditions: Overweight|Microbiota|Endotoxemia|Metabolic Syndrome|Non-Alcoholic Fatty Liver Disease|Insulin Resistance
Interventions: OTHER: Maple syrup|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Effects of ONO-2952 on Pain Perception Produced by Rectal Distention in Female Subjects With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)
Status: TERMINATED
Conditions: Irritable Bowel Syndrome (IBS)
Interventions: DRUG: ONO-2952|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Aerobic Training on the Health Parameters of Postmenopausal Women With Multimorbidity
Status: SUSPENDED
Conditions: Multimorbidity|Multiple Chronic Conditions|Hypertension|Dyslipidemias
Interventions: BEHAVIORAL: Aerobic training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: COST (COvid STudio) ACTION: Study for the Evaluation of Specific Antibodies Anti Covid-19 Linked to Covid-19 Infection, Symptoms and Genetic Expression of ACE2 Polymorphisms in Patients (COST ACTION)
Status: UNKNOWN
Conditions: COVID-19
Interventions: OTHER: BioMedomics COVID-19 IgM-IgG Rapid Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ebastine Versus Mebeverine in IBS Patients
Status: RECRUITING
Conditions: IBS - Irritable Bowel Syndrome|IBS
Interventions: DRUG: Ebastine|DRUG: Duspatalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Combination Therapies to Treat COVID-19 Infection
Status: WITHDRAWN
Conditions: COVID|COVID-19|Corona Virus Infection|Coronavirus Infection|Coronavirus Sars-Associated as Cause of Disease Classified Elsewhere|Coronavirus-19|SARS-CoV 2|SARS Pneumonia
Interventions: DRUG: hydroxychloroquine|DRUG: Azithromycin|DRUG: Ritonavir|DRUG: Lopinavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Increased-Dose Abiraterone Acetate in Patients With Castration Resistant Prostate Cancer
Status: COMPLETED
Conditions: Castration Resistant Prostate Cancer
Interventions: DRUG: Abiraterone Acetate|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pathogenesis of Hematologic Malignancies
Status: ENROLLING_BY_INVITATION
Conditions: Acute Leukemia|Lymphoproliferative Disorders|Myeloproliferative Disorders|Myelodysplastic Syndromes
Interventions: PROCEDURE: blood draw, bone marrow procedure, or tissue biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optimal Duration of Anticoagulation Therapy for Isolated Distal Deep Vein Thrombosis in Patients With Cancer Study
Status: COMPLETED
Conditions: Venous Thrombosis|Neoplasms|Anticoagulant
Interventions: DRUG: 12-month Edoxaban|DRUG: 3-month Edoxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psycho-educational Intervention Programme for Comprehensive Preparation for Retirement: Study Protocol
Status: NOT_YET_RECRUITING
Conditions: Aging|Adaptation|Psychosocial Factors|Psychology|Older People|Retirement
Interventions: BEHAVIORAL: Psychoeducational Programme|BEHAVIORAL: Education Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Rosuvastatin in HIV-Infected Subjects to Modulate Cardiovascular Risks
Status: COMPLETED
Conditions: HIV Infections|Heart Disease
Interventions: DRUG: Rosuvastatin 10 mg. daily for 96 weeks|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Camrelizumab Plus Apatinib and Chemotherapy as Neoadjuvant Therapy in Participants With Triple Negative Breast Cancer (TNBC)
Status: RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Camrelizumab|DRUG: Apatinib|DRUG: Nab-paclitaxel|DRUG: Epirubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiretrovirals Combined With Antibodies for HIV-1 Cure In Africa
Status: NOT_YET_RECRUITING
Conditions: HIV-1-infection
Interventions: DRUG: 3BNC117-LS|DRUG: 10-1074-LS|DRUG: Placebo for 3BNC117-LS|DRUG: Placebo for 10-1074-LS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Cetuximab (Erbitux®), Capecitabine and Radiotherapy in Neoadjuvant Treatment of Patients With Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: DRUG: cetuximab, capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomised, Parallel-group, Double-blind, Double-dummy Study to Compare the Effects of Lacidipine Versus Bendrofluazide on Markers of Platelet Activation and Haemorheological Factors in Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Lacidipine|DRUG: Bendrofluazide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Adult Growth Hormone Deficiency and Cardiovascular Risk
Status: TERMINATED
Conditions: Growth Hormone Deficiency
Interventions: PROCEDURE: Blood draws|DRUG: growth hormone releasing hormone (GHRH) & arginine|PROCEDURE: Carotid ultrasound|PROCEDURE: MRI|PROCEDURE: Endothelial cell biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Horizontal Ridge Augmentation With or Without Autogenous Block Grafts
Status: COMPLETED
Conditions: Bone Regeneration|Bone Transplantation|Bone Substitutes|Cone-beam Computed Tomography|Dental Implants
Interventions: PROCEDURE: Horizontal ridge augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Fentanyl on the Occurrence of Postoperative Nausea and Vomiting According to Time of Administration Around the End of Tonsillectomy With or Without Adenoidectomy
Status: COMPLETED
Conditions: Follicular Tonsillitis (Chronic)
Interventions: DRUG: fentanyl at 10-15 min before end of surgery|DRUG: fentanyl at end of surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dietary Strategy to Tackle Sarcopenia in Early Elderly Subjects (FOOP-Sarc)
Status: RECRUITING
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Refined olive oil (38.6 mg hydroxytyrosol and tyrosol/kg oil)|DIETARY_SUPPLEMENT: Virgin olive oil rich in phenolic compounds (156 mg hydroxytyrosol and tyrosol/kg oil)|DIETARY_SUPPLEMENT: Maltodextrin|DIETARY_SUPPLEMENT: Prebiotic (FOS and inulin)|OTHER: Nutritional and physical activity recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Haloperidol Prophylaxis in Cardiac Surgery for Patients at Risk for Delirium
Status: COMPLETED
Conditions: Postoperative Confusion
Interventions: DRUG: Haloperidol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy and Bone Marrow Transplantation in Treating Patients With Leukemia or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cytarabine|PROCEDURE: allogeneic bone marrow transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Novel Text-Messaging Bot in Patients Undergoing Joint Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Osteoarthritis, Hip
Interventions: OTHER: Automated Text Messaging (SMS) Bot (intervention group)|OTHER: Routine perioperative education & teaching (control group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinic Trial to Evaluate the Safety and Immunogenicity by Different Sequential Schedules of bOPV and IPV
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: 1-dose cIPV + 2-doses bOPV (Candy)|BIOLOGICAL: 1-dose sIPV + 2-doses bOPV (Candy)|BIOLOGICAL: 2-doses cIPV + 1-dose bOPV (Candy)|BIOLOGICAL: 2-doses sIPV + 1-dose bOPV (Candy)|BIOLOGICAL: 2-doses cIPV + 1-dose tOPV (Candy)|BIOLOGICAL: 2-doses sIPV + 1-dose tOPV (Candy)|BIOLOGICAL: 1-dose cIPV + 2-doses bOPV (Liquid)|BIOLOGICAL: 1-dose sIPV + 2-doses bOPV (Liquid)|BIOLOGICAL: 2-doses cIPV + 1-dose bOPV (Liquid)|BIOLOGICAL: 2-doses sIPV + 1-dose bOPV (Liquid)|BIOLOGICAL: 2-doses cIPV + 1-dose tOPV (Liquid)|BIOLOGICAL: 2-doses sIPV + 1-dose tOPV (Liquid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Rutin and Vitamin C Combination on Oxidative Stress, Insulin Sensitivity and Lipid Profile in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Rutin in combination with Vitamin C|DIETARY_SUPPLEMENT: Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Postoperative Drain Insertion Versus No Drain Insertion In Total Laparoscopic Hysterectomy
Status: UNKNOWN
Conditions: TOTAL ABDOMINAL HYSTERECTOMY
Interventions: PROCEDURE: SURGICAL DRAIN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Shoulder Stretching and Percussive Massage on Shoulder Rotation and Attack Speed in Female Volleyball Players
Status: COMPLETED
Conditions: Sports Physical Therapy
Interventions: DEVICE: The Percussive Massage Treatment|BEHAVIORAL: The Proprioceptive Neuromuscular Facilitation Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Unilateral Versus Bilateral Lower-Limb Plyometric Training in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Unilateral plyometric training|OTHER: Bilateral plyometric training|OTHER: Standard physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fibre and Gas in Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Inulin|DIETARY_SUPPLEMENT: Psyllium|DIETARY_SUPPLEMENT: Inulin and psyllium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of a Nutritional Technology for Vitamin D Absorption
Status: COMPLETED
Conditions: Nutrition, Healthy
Interventions: OTHER: Experimental Oil with Phospholipids|OTHER: Control Polyunsaturated Oil Blend
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study Of Dacomitinib (PF-00299804) In Advanced NSCLC Patients (Post Chemo Or Select First Line) To Evaluate Prophylactic Intervention On Derm And GI AEs And PRO
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Dacomitinib|DRUG: Dacomitinib|DRUG: Doxycycline|DRUG: Probiotic|DRUG: Alclometasone cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Goat Cheese Effect in Lipid Profile Change
Status: COMPLETED
Conditions: Obesity and Overweight
Interventions: DIETARY_SUPPLEMENT: Functional goat cheese|DIETARY_SUPPLEMENT: Control cheese
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Study Of BIIB118 (PF-05251749) In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Adult Subjects|Healthy Elderly Subjects
Interventions: DRUG: BIIB118|DRUG: Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sirolimus, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients At High Risk for Cholangiocarcinoma Recurrence After Liver Transplant or Surgery
Status: COMPLETED
Conditions: Hepatic Complication
Interventions: DRUG: Cisplatin|DRUG: Gemcitabine Hydrochloride|OTHER: Quality-of-Life Assessment|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Evaluate the Safety and Effectiveness of Once Weekly or Once Every Two Week Dosing of Epoetin Alfa in Anemic Patients With Low- or Intermediate-1 Risk Myelodysplastic Syndromes (MDS)
Status: WITHDRAWN
Conditions: Myelodysplastic Syndromes|Anemia
Interventions: DRUG: Epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Parotid-gland Sparing IMRT in Patients With Midline Tumour of the Head and Neck
Status: COMPLETED
Conditions: Oropharyngeal Squamous Cell Cancer|Hypopharyngeal Squamous Cell Cancer
Interventions: RADIATION: Intensity modulated radiotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Remote Ischemic Conditioning on Hand Use in Individuals With Spinal Cord Injury and Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Spinal Cord Injuries|Amyotrophic Lateral Sclerosis
Interventions: OTHER: Active Remote Ischemic Conditioning|OTHER: Sham Remote Ischemic Conditioning|OTHER: Isometric hand exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial to Determine the Efficacy and Safety of JCAR017 in Adult Participants With Aggressive B-Cell Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: JCAR017
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Soticlestat in Healthy Adults To Evaluate the Effect on QTc Interval
Status: WITHDRAWN
Conditions: Healthy Volunteers
Interventions: DRUG: Soticlestat|DRUG: Placebo|DRUG: Moxifloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: XKDCT080 in GCC-positive Recurrent or Refractory Solid Tumors With Single Center, Single Arm, and Dose Escalation
Status: RECRUITING
Conditions: Colon Cancer
Interventions: DRUG: Chimeric antigen receptor T cell preparation targeting GCC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Impairment and Cerebral Haemodynamics in Individuals With Symptomatic Peripheral Arterial Disease
Status: NOT_YET_RECRUITING
Conditions: Peripheral Arterial Disease|Cognitive Impairment
Interventions: DIAGNOSTIC_TEST: Cerebral haemodynamic testing using transcranial Doppler|DIAGNOSTIC_TEST: Ankle-brachial pressure index|DIAGNOSTIC_TEST: Six-minute walk test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Safety, Tolerability and Effectiveness of Hydroxychloroquine and Itraconazole in Platinum-resistant Epithelial Ovarian Cancer
Status: COMPLETED
Conditions: Platinum-resistant Epithelial Ovarian Cancer
Interventions: DRUG: Hydroxychloroquine|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiplatelet Secondary Prevention International Randomised Trial After INtracerebral haemorrhaGe (ASPIRING)-Pilot Phase
Status: ACTIVE_NOT_RECRUITING
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: Start antiplatelet monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intraoperative Fluid Management in Laparoscopic Bariatric Surgery
Status: COMPLETED
Conditions: Morbid Obesity|Acidosis|Intra-Abdominal Abscess|Hemorrhage|Reflux|Vomiting
Interventions: DRUG: Lactated Ringer's solution|DRUG: Lactated Ringer's solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impaired Gustatory Sensory Perception in Obese and Obese Diabetic Persons
Status: TERMINATED
Conditions: Obesity|Diabetes
Interventions: OTHER: Recording of GEP (Gustatory Evoked Potentials)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effectiveness of Oral Dexamethasone for Acute Bronchiolitis
Status: COMPLETED
Conditions: Bronchiolitis, Viral
Interventions: DRUG: dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Color Lights on the Internal Clock and Alertness in Humans
Status: UNKNOWN
Conditions: Light Flashing
Interventions: OTHER: Flickering light stimuli|OTHER: Constant light stimuli|OTHER: Dim light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cyclophosphamide Versus Mycophenolate Mofetil in Lupus Nephritis
Status: COMPLETED
Conditions: To Compare the Effects of Mycophenolate Mofetil With Cyclophosphamide in Neplaese Lupus Nephritis Patients
Interventions: DRUG: Cyclophosphamide|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Romidepsin CHOP vs CHOP in Patients With Untreated Peripheral T-Cell Lymphoma
Status: COMPLETED
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: Romidepsin + CHOP|DRUG: CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparisons of the Impact of Monotherapy With Mirabegron or Tolterodine Versus Combined Treatment With Mirabegron and Tolterodine on Autonomic Function and Bladder Blow Flow in Women With Overactive Bladder Syndrome: a Randomized Controlled Study
Status: RECRUITING
Conditions: Female Patients With Overactive Bladder Syndrome
Interventions: DRUG: tolterodine|DRUG: mirabegron|DRUG: tolterodine , mirabegron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Relationships Between Refractory Hypertension, Overweight/Obesity and Sleep Apnea Syndrome
Status: COMPLETED
Conditions: Refractory Hypertension
Interventions: DEVICE: nCPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Awake Prone Position to Reduce Ventilation Inhomogeneity in COVID-19 Acute Respiratory Failure
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: OTHER: physiological effects of awake prone position in COVID 19 patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Risk Stratification Oriented Treatment of Pediatric Ewing Sarcoma: a Prospective Multicenter Cohort Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Ewing Sarcoma|Risk Stratification
Interventions: DRUG: cyclophosphamide, adriamycin, vincristine，Ifosfamide，etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout
Status: RECRUITING
Conditions: Gout
Interventions: DRUG: Allopurinol|DRUG: Naproxen 250 MG|DRUG: Colchicine 0.6 mg|DRUG: Colchicine 1.2 mg|DRUG: Naproxen 500 Mg|DRUG: Prednisone 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does the Thrombin Generation Test Performed During the Pharmacokinetic Profile of the Substitutive Factor VIII Bring Benefits to the Personalized Treatment of Pediatric Patients and Adult Hemophilia A Patients Under Prophylaxis ?
Status: RECRUITING
Conditions: Hemophilia
Interventions: DEVICE: Chronometric method|DEVICE: Chromogenic method|DEVICE: Thrombin generation test (TGT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Exercise and Cognitive-psychosocial Functions in Men With Prostate Cancer Receiving Androgen Depletion Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MRgFUS and RFA for Treatment of Facet-joint Osteoarthritis Low Back Pain
Status: RECRUITING
Conditions: Chronic Low Back Pain|Facet Joint Syndrome
Interventions: PROCEDURE: MRgFUS ablation|PROCEDURE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of 5 Tablets of 100 mg Versus 2 Tablets of 250 mg TF3 of Tepotinib
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tepotinib 100 mg|DRUG: Tepotinib 250 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Specialized Addiction Treatment Versus Treatment as Usual for Young Patients With Cannabis Abuse and Psychosis
Status: COMPLETED
Conditions: Marijuana Abuse|Psychotic Disorders|Schizophrenia
Interventions: BEHAVIORAL: Cognitive behavioral therapy with motivational interviewing|BEHAVIORAL: Non-manualized standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT