pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Programm Interest 'Bouge' to Improve the Daily Physical Activity at the Pregnant Women.
Status: UNKNOWN
Conditions: Physical Activity|Pregnant|Mobile Health Apps
Interventions: DEVICE: Smartphone application "placebo"|DEVICE: Smartphone equipped with application "bouge" = Coach group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Adalimumab (Humira) on Vascular Abnormalities in Rheumatoid Arthritis. A Pilot Study.
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Comparison of Polyethylene Glycol Loxenatide and Gliclazide on the Brain Function in T2DM Patients
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus|Cognitive Function Abnormal
Interventions: DRUG: loxenatide Group|DRUG: Gliclazide Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrated Smart Speaker Promoting Positive Parenting Among Caregivers of Youth With Challenging Behaviors
Status: RECRUITING
Conditions: Oppositional Defiant Disorder|Conduct Disorder
Interventions: BEHAVIORAL: FamilyNet smart speaker/mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial in Antiaggregated Patients With Proximal Femur Fracture Evaluating a Strategy to Shorten Time Until Surgery
Status: COMPLETED
Conditions: Femur Fracture
Interventions: DIAGNOSTIC_TEST: Platelet function assay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pharmacokinetics and Pharmacodynamics of MTR105 in Hypotensive Cardiac Surgery Patients
Status: WITHDRAWN
Conditions: Hypotension|Cardiopulmonary Bypass
Interventions: DRUG: MTR105
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of GangTrainer GT1, Lokomat and Conventional Physiotherapy
Status: SUSPENDED
Conditions: Stroke, Acute
Interventions: DEVICE: GangTrainer GT1|DEVICE: Lokomat|OTHER: Conventional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Pharmacokinetics of ASP1941 and the Effect on Glucose Concentrations in Male and Female Young and Elderly Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteers|Pharmacokinetics of ASP1941
Interventions: DRUG: ASP1941|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Daily Living Skills Intervention for Adolescents With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Surviving and Thriving in the Real World|BEHAVIORAL: Program for the Education and Enrichment of Relational Skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Monthly Darbepoetin Alfa Dosing for Correction of Anemia in Non-dialysis Chronic Kidney Disease
Status: COMPLETED
Conditions: Anemia|Chronic Kidney Disease
Interventions: DRUG: darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Negative Pressure Wound Therapy for High Risk Laparotomy Wounds. A Randomized Prospective Clinical Trial.
Status: TERMINATED
Conditions: Surgical Wound|Wound Dehiscence, Surgical|Surgical Site Infection|Dehiscence of Internal Surgical Wound
Interventions: DEVICE: Prophylactic negative pressure wound dressing after laparotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PS-341 and Combination Chemotherapy in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: bortezomib|DRUG: paclitaxel|DRUG: carboplatin|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 6-week Study to Evaluate the Efficacy and Safety of Lurasidone HCL in Acutely Psychotic Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Lurasidone HCL 160 mg|DRUG: Quetiapine XR 600 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bone and Inflammatory Outcomes - Nutrition and Exercise Trials
Status: RECRUITING
Conditions: Healthy|Bone|Inflammation
Interventions: BEHAVIORAL: High-Intensity Exercise|DIETARY_SUPPLEMENT: Carbohydrate (Maltodextrin powder mixed with water)|DIETARY_SUPPLEMENT: Skim Milk|DIETARY_SUPPLEMENT: Greek yogurt|DIETARY_SUPPLEMENT: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Targeted Health Coaching to Improve Physical Activity Post-Structured Cardiac Rehabilitation
Status: COMPLETED
Conditions: Cardiac Rehabilitation|Health Coaching|Physical Activity
Interventions: BEHAVIORAL: Targeted Health Coaching Group|BEHAVIORAL: Standard Care Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized, Double-blind, Placebo-controlled Cannabis Extract x Placebo for Cocaine Addicts
Status: RECRUITING
Conditions: Cocaine Dependence
Interventions: DRUG: Cannabis Extract Oil SR Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Study to Evaluate Efficacy and Safety of Imotun Capsule in Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Imotun capsule|DRUG: Imotun capsule placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does ESPB Improve Postoperative Quality of Recovery After VATS
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Ropivacaine Injection|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transabdominal Preperitoneal Inguinal Hernia Repair
Status: RECRUITING
Conditions: Hernia, Inguinal|Laparoscopy
Interventions: PROCEDURE: Robotic TAPP|PROCEDURE: Laparoscopic TAPP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Derived Exosomes in the Treatment of Melasma and Its Percutaneous Penetration
Status: RECRUITING
Conditions: Melasma
Interventions: PROCEDURE: 1565 nm non-ablative fractional laser combined with normal saline|PROCEDURE: microneedles combined with hUCMSC-Exos|PROCEDURE: 1565 nm non-ablative fractional laser combined with hUCMSC-Exos|PROCEDURE: PBASM combined with hUCMSC-Exos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ambisome and Management of Culture-negative Neutropenic Fever Unresponsive to Antibiotics
Status: TERMINATED
Conditions: Febrile Neutropenia
Interventions: DRUG: Liposomal amphotericin B (AmBisome®)|DRUG: Liposomal amphotericin B (AmBisome®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Urology of Virginia Case Series
Status: COMPLETED
Conditions: Prostate Cancer|Cancer of the PROSTATE|Prostatic Neoplasm
Interventions: DEVICE: Ultrasound guided prostate exam using SOC ultrasound system|DEVICE: mpMRI guided prostate examination using PI-RADS v2|DEVICE: High-resolution micro-ultrasound guided prostate biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Remote Prescribed and Monitored Exercise Program After Pulmonary Rehabilitation in Individuals With Chronic Lung Disease
Status: UNKNOWN
Conditions: Pulmonary Disease, Chronic Obstructive|Rehabilitation
Interventions: OTHER: Remote Exercise Prescription|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Autonomic Neural Regulation Therapy to Enhance Myocardial Function in Heart Failure (ANTHEM-HF) Study
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DEVICE: Vagus Nerve Stimulation (VNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Nasal Surgery at the Time of Le Fort I Osteotomy: A Prospective, Single-blind, Randomized Trial
Status: UNKNOWN
Conditions: Surgical Procedure, Unspecified
Interventions: PROCEDURE: Septoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment With Recombinant Human Growth Hormone (GH) in Children With Short Stature Secondary to a Long Term Corticoid Therapy
Status: TERMINATED
Conditions: Endocrine System Diseases
Interventions: DRUG: Somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Radial and Femoral Approach in Primary Percutaneous Coronary Intervention (PCI)
Status: COMPLETED
Conditions: ST Elevation Myocardial Infarction
Interventions: PROCEDURE: Access site in primary PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Efficacy and Safety of Stivant (AryoGen Bevacizumab) Versus Avastin in Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Bevacizumab + FOLFIRI-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bilateral Thoracic Paravertebral Blocks in Obese and Non-obese Patients Undergoing Reduction Mammaplasty
Status: COMPLETED
Conditions: Pain, Postoperative|Obesity|Thoracic Paravertebral Blocks|Ultrasound|Performance
Interventions: PROCEDURE: Bilateral Thoracic paravertebral block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Effect of Inositol Supplementation in Overweight Children on Basal Insulin and Body Weight
Status: UNKNOWN
Conditions: Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Inofolic Combi|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain and Glycemic Responses to Sweet Soft Drinks
Status: COMPLETED
Conditions: Normal Physiological Response to Sweet Drinks
Interventions: OTHER: Water (reference)|OTHER: Sucrose|OTHER: Sucralose|OTHER: Stevia|OTHER: Monk fruit|OTHER: Allulose + stevia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pericapsular Nerve Group Block for Positional Pain and Postoperative Analgesia in Hip Fractures
Status: UNKNOWN
Conditions: Pertrochanteric Fracture|Pain, Postoperative
Interventions: PROCEDURE: Pericapsular nerve group blockade|DRUG: Midazolam Ketamine arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression
Status: RECRUITING
Conditions: Opioid Use|Lumbar Spinal Stenosis|Pain, Postoperative|Pain, Back
Interventions: DRUG: Depo-Medrol 40Mg/Ml Suspension for Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Hyperphagia Behavioral Symptoms in Children and Adults Diagnosed With Prader-Willi Syndrome
Status: COMPLETED
Conditions: Hyperphagia in Prader-Willi Syndrome
Interventions: DRUG: FE 992097|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Cryoballoon Pulmonary Vein Isolation vs. Cryoballoon Pulmonary Vein Isolation With Additional Right Atrial Linear Ablation for Persistent Atrial Fibrillation (CRARAL Trial)
Status: ACTIVE_NOT_RECRUITING
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: Cryoballoon PV isolation group|PROCEDURE: Cryoballoon PV isolation with Additional RA linear ablation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Different Alveolar Ridge Preservation Techniques
Status: UNKNOWN
Conditions: Loss of Teeth Due to Extraction
Interventions: DEVICE: dense polytetrafluoroethylene (dPTFE) membrane Cytoplast|DEVICE: human amniotic-tissue derived membrane BioXclude|PROCEDURE: Ridge Preservation with overlay graft|PROCEDURE: Ridge Preservation without overlay graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Preparation on Bacterial Colonization of the Pharyngeal Mucosa in Surgery of Head and Neck Cancer
Status: COMPLETED
Conditions: Bacterial Infection
Interventions: DRUG: Chlorhexidine|DEVICE: NaCl 0.9 %
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate Clinical Research From Commerical Oral Care Products
Status: COMPLETED
Conditions: Gingival Diseases
Interventions: DRUG: Fluoride|DRUG: Triclosan/Fluoride|DRUG: Chlorhexidine Gluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Genicular Artery Embolisation for Knee Osteoarthritis II
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Genicular Artery Embolisation|PROCEDURE: Genicular Artery Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of Seroprevalence of Anti-SARS-CoV2 Among Children of Hospital Workers in AP-HP
Status: COMPLETED
Conditions: SARS-CoV2
Interventions: BIOLOGICAL: Serology SARS-CoV2|BEHAVIORAL: Data collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Neurophysiological Effect of Mindfulness-Based Stress Reduction (MBSR) Training on Emotional Regulation
Status: UNKNOWN
Conditions: Mindfulness-based Stress Reduction
Interventions: BEHAVIORAL: Mindfulness-based Stress Reduction(MBSR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-IH [In Hospital] Trial
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: PROCEDURE: Therapeutic Hypothermia|PROCEDURE: Therapeutic Normothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy Plus QS21 in Treating Patients With Advanced Pancreatic or Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Pancreatic Cancer
Interventions: BIOLOGICAL: QS21|BIOLOGICAL: ras peptide cancer vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: Ocrelizumab for Psychosis by Autoimmunity
Status: RECRUITING
Conditions: Schizo-Affective Type of Psychosis|Schizophrenia
Interventions: BEHAVIORAL: Psychosis and cognitive assessments|BEHAVIORAL: Physical and neuro-cognitive evaluations|DIAGNOSTIC_TEST: Safety labs and electrocardiogram|BIOLOGICAL: Ocrelizumab infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Safety and Efficacy of the Drug Larotrectinib for the Treatment of Tumors With NTRK-fusion in Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumors Harboring NTRK Fusion
Interventions: DRUG: Larotrectinib (Vitrakvi, BAY2757556)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Corneal Collagen Cross-Linking in Eyes With Keratoconus
Status: COMPLETED
Conditions: Keratoconus
Interventions: DRUG: riboflavin solution|DRUG: placebo solution|DEVICE: KXL System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mobilization of Stem Cells With Plerixafor, Chemotherapy and G-CSF in Multiple Myeloma or Non-Hodgkin's Lymphoma Patients
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|Multiple Myeloma
Interventions: DRUG: G-CSF and plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of ACZONE™ (Dapsone) Gel, 5% As a Treatment For Tarceva® (Erlotinib)Related Rash
Status: TERMINATED
Conditions: Rash|Non-small-Cell Lung Cancer
Interventions: DRUG: ACZONE (dapsone) Gel, 5%|DRUG: Vehicle Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Phase II/III Study to Evaluate the Immunogenicity and Safety and Efficacy of SWIM816 Vaccines for SARS-CoV-2
Status: NOT_YET_RECRUITING
Conditions: Immunogenicity|Safety
Interventions: BIOLOGICAL: Phase II:SWIM816;SARS-Cov-2;|BIOLOGICAL: Phase II:SW-BIC-213;SARS-Cov-2;|BIOLOGICAL: PhaseIII:SWIM816;SARS-Cov-2;|BIOLOGICAL: PhaseIII:Pfizer(Pfizer Bivalent vaccine);SARS-Cov-2；
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of Single Tufted Brush in the Management of Peri-implant Mucositis
Status: UNKNOWN
Conditions: Dental Implant
Interventions: DEVICE: single tufted brush with IDB|DEVICE: interdental brushes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multi-dose Acetaminophen for Patients Undergoing General Anesthesia
Status: TERMINATED
Conditions: Recovery Following Cholecystectomy
Interventions: DRUG: Acetaminophen|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics (PK) and Safety of a Single Intravenous (IV) Dose of MK-3866 in Participants With Impaired Renal Function and in Healthy Controls (MK-3866-005)
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: MK-3866
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Amount of Drug in the Blood After a Single Tablet EC905 Containing Solifenacin and Tamsulosin is Taken by Healthy Males Compared to Separate Tablets of Solifenacin and Tamsulosin
Status: COMPLETED
Conditions: EC905|Pharmacokinetics|Healthy Subjects
Interventions: DRUG: EC905|DRUG: solifenacin|DRUG: tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Attaining and Maintaining Wellness in Obsessive-compulsive Disorder
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: BEHAVIORAL: Monthly Booster Sessions of EX/RP|PROCEDURE: Visits with MD and independent evaluators
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intranasal Steroids and Oxymetazoline in Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Fluticasone furoate|DRUG: Placebo Fluticasone furoate|DRUG: Oxymetazoline|DRUG: Placebo Oxymetazoline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Vertebroplasty vs. Sham for Osteoporotic Vertebral Compression Fractures Focusing on Pain and Economy.
Status: RECRUITING
Conditions: Osteoporotic Fractures|Vertebral Fracture
Interventions: PROCEDURE: Vertebroplasty|PROCEDURE: Sham Vertebroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Muscle Reflex Inhibition in Hypoxic Exercise
Status: NOT_YET_RECRUITING
Conditions: Dyspnea|Muscle Strain
Interventions: DRUG: Fentanyl|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Advancing Chemical and Genomic Strategies for Relapsed/Refractory T-ALL and ETP-ALL
Status: RECRUITING
Conditions: T Acute Lymphoblastic Leukemia|Early T Acute Lymphoblastic Leukemia|T-lymphoblastic Lymphoma|Etp All
Interventions: OTHER: bone marrow and/or peripheral blood samples withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Feto-Endoscopic Tracheal Occlusion (FETO) for Left Congenital Diaphragmatic Hernia
Status: RECRUITING
Conditions: Congenital Diaphragmatic Hernia|Pulmonary Hypoplasia|Pulmonary; Hypertension
Interventions: DEVICE: Fetal Tracheal Occlusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer|Small-cell Lung Cancer|Non Small Cell Lung Cancer
Interventions: DRUG: Carboplatin|DRUG: Pemetrexed|DRUG: Paclitaxel|DRUG: Nab paclitaxel|DRUG: Docetaxel|DRUG: Gemcitabine|DRUG: Etoposide|DRUG: Irinotecan|DRUG: Topotecan|DRUG: Lurbinectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Myocardial Deformation and Coronary Artery Tortuosity in Patients With Hypertrophic Cardiomyopathy
Status: COMPLETED
Conditions: Myocardial Deformation|Coronary Artery Anomaly|Hypertrophic Cardiomyopathy|Genetic Mutation|Prognosis
Interventions: OTHER: no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Retrospective, Observational, Monocenter, Study to Describe the Utilization and Overall Safety and Performance of POLYSITE®/SEESITE® Implantable Ports
Status: COMPLETED
Conditions: Venous System|Venous Access|Chemotherapy|Antibiotics|Antiviral|Parenteral Nutrition|Transfusion Blood
Interventions: DEVICE: Central Veinous access devices' insertion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Pragmatic Shoulder Technique VS Traditional Physical Therapy
Status: COMPLETED
Conditions: Shoulder Pain|Shoulder Impingement|Shoulder Injuries|Frozen Shoulder|Shoulder Capsulitis
Interventions: OTHER: set of pragmatic shoulder technique|OTHER: traditional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploit the Neural Source and the Feasibility of Transcranial Direct Current Stimulation for Freezing of Gait in Parkinson's Disease and Multiple System Atrophy
Status: UNKNOWN
Conditions: Parkinson's Disease|Multiple System Atrophy
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CLamp vs Off Clamp Kidney During Partial Nephrectomy
Status: UNKNOWN
Conditions: Nephrectomy|Kidney Neoplasm|Glomerular Filtration Rate
Interventions: PROCEDURE: Clamp Robotic partial nephrectomy|PROCEDURE: Clampless Robotic partial nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation-Free Heart Catheterization Using MRI
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Coarctation|Cardiomyopathy|Atrial Septal Defect|Aortic Stenosis|Post Heart Transplant Catheter Procedure|Patent Ductus Arteriosus
Interventions: PROCEDURE: MRI guided cardiac catheterization|DEVICE: Magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Preventing Malnutrition and Restoring Nutritional Status in Hospitalized Children
Status: COMPLETED
Conditions: Nutrition Disorders
Interventions: PROCEDURE: Access to a Computerized Clinical Decision Support System (CCDDS)|BEHAVIORAL: Education of Healthcare workers|OTHER: Local assistance by a dietician
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Closure of Muscular Ventricular Septal Defects (VSDs) With the AMPLATZER Muscular VSD (MuVSD) Occluder - Post Approval Study
Status: COMPLETED
Conditions: Ventricular Septal Defects
Interventions: DEVICE: Muscular VSD Occluder device implantation (AMPLATZER Muscular VSD Occluder)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and PCSK9 Inhibitor for pMMR/MSS Locally Advanced Mid-low Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Rectal Cancer
Interventions: COMBINATION_PRODUCT: Long-course chemoradiation and PD-1 inhibitor, with PCSK9 inhibitor|COMBINATION_PRODUCT: Long-course chemoradiation and PD-1 inhibitor, without PCSK9 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Concomitant Use of ACell MicroMatrix® and ACell Cytal™ to Standard of Care in Stage 3 or 4 Pressure Injuries
Status: COMPLETED
Conditions: Pressure Ulcers Stage III|Pressure Ulcer, Stage IV|Pressure Ulcer
Interventions: DEVICE: MicroMatrix® and Cytal™ Wound Matrix 2-Layer|DEVICE: MicroMatrix® and Cytal™ Wound Matrix 2-Layer plus NPWT|DEVICE: Negative Pressure Wound Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Different Volumes in Erector Spinae Plane Block in Single Level Lumbar Spine Fixation
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: Bupivacaine 0.25% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Typhoid Vaccine in Testing Response to Immune Stress in Patients With Stage I-IIIA Breast Cancer
Status: COMPLETED
Conditions: Cognitive Side Effects of Cancer Therapy|Depression|Recurrent Breast Carcinoma|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage IIIA Breast Cancer
Interventions: BIOLOGICAL: typhoid vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Feasibility and Effects of KOL-webben in Patients With COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: BEHAVIORAL: KOLwebben
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of the Euploid Rate of Blastocyst Between PPOS and GnRH Antagonist Protocol in Women With PCOS Undergoing PGT-A
Status: NOT_YET_RECRUITING
Conditions: Preimplantation Genetic Testing|Progestin-primed Ovarian Stimulation|Polycystic Ovarian Syndrome|GnRH Antagonist
Interventions: DRUG: GnRH antagonist|DRUG: MPA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR)
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Solid Tumor|Metastatic Solid Tumor
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: ACE2016|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Drug Absorption Into the Blood After Administration of 3 Doses of AZD5718
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Treatment A|DRUG: Treatment B|DRUG: Treatment C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Challenges in IC (and Male CPPS)
Status: COMPLETED
Conditions: Chronic Prostatitis With Chronic Pelvic Pain Syndrome|Chronic Bacterial Prostatitis|Asymptomatic Inflammatory Prostatitis|Painful Bladder Syndrome|Cystitis, Interstitial
Interventions: GENETIC: Genomic and proteomic biomarker discovery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EXCOR Active Driving System for the EXCOR Pediatric VAD IDE Study
Status: RECRUITING
Conditions: Heart Failure|Transplant; Failure, Heart|Congenital Heart Disease
Interventions: DEVICE: EXCOR Active Driving System for Pediatric VAD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Awareness Detection and Communication in Disorders of Consciousness
Status: RECRUITING
Conditions: Disorder of Consciousness|Paralysis|Motor Neuron Disease|Stroke|Physical Disability
Interventions: OTHER: Motor imagery based EEG-BCI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of Electrophysiological Effects of Dabigatran Etexilate as Single Dose on the QT Interval in Healthy Female and Male Subjects.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dabigatran etexilate low|DRUG: Dabigatran etexilate high|DRUG: Moxifloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparing Intravitreal Aflibercept Monotherapy vs Aflibercept Combined With Reduced Fluence PDT in PCV Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Polypoidal Choroidal Vasculopathy
Interventions: DRUG: Aflibercept + reduced fluence photodynamic therapy (RF-PDT)|DRUG: Aflibercept + sham reduced fluence photodynamic therapy (RF-PDT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy for Diabetic Neuropathic Pain
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: BEHAVIORAL: CBT plus standard pharmaceutical care (CBT/SC)|BEHAVIORAL: Diabetic Education plus standard pharmaceutical care (ED/SC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Plus Bevacizumab and Chemotherapy for Non-Squamous NSCLC Patients
Status: RECRUITING
Conditions: Non-squamous NSCLC
Interventions: BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Bevacizumab|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Carboplatin|DIETARY_SUPPLEMENT: Folic acid 350-1000 μg|DIETARY_SUPPLEMENT: Vitamin B12 1000 μg|DRUG: Dexamethasone 4 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Comeback Study
Status: COMPLETED
Conditions: Chronic Fatigue Syndrome|Myalgic Encephalomyelitis
Interventions: BIOLOGICAL: Preprocessed thawed donor FMT|BIOLOGICAL: Preprocessed thawed autologous FMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab in Treating Patients With Intermediate or High-Risk Smoldering Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoldering Plasma Cell Myeloma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shaeer's Vein Ligation-I: Internal Pudendal Vein Sub-Gluteal Ligation For Veno Occlusive Erectile Dysfunction
Status: NOT_YET_RECRUITING
Conditions: Erectile Dysfunction
Interventions: PROCEDURE: Shaeer-I|PROCEDURE: PPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of BioNIR Drug Eluting Stent System in Coronary Stenosis
Status: COMPLETED
Conditions: Coronary Artery Stenosis
Interventions: DEVICE: BioNIR|DEVICE: Resolute
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Musical Auditory Training on Subjects With Tinnitus Disorder
Status: RECRUITING
Conditions: Tinnitus
Interventions: BEHAVIORAL: Treinamento Auditivo Musical|BEHAVIORAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Idasanutlin and Selinexor Therapy for Children With Progressive/Relapsed AT/RT or Extra-CNS Malignant Rhabdoid Tumors
Status: WITHDRAWN
Conditions: Rhabdoid Tumor|Atypical Teratoid/Rhabdoid Tumor|Atypical Teratoid/Rhabdoid Tumor of CNS|CNS Tumor
Interventions: DRUG: Idasanutlin|DRUG: Idasanutlin|DRUG: Selinexor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Delayed Small-Bowel Anastomosis in Patients With Postoperative Peritonitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Postoperative Peritonitis|Anastomotic Leakage|Intestinal Perforation Small
Interventions: PROCEDURE: Primary anastomosis|PROCEDURE: Delayed anastomosis|PROCEDURE: Enterostomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nocturnal Oxygenation and Sleep-related Breathing Disorders During the First Night of a Stay at 2500m of High Altitude in Patients With Precapillary Pulmonary Hypertension
Status: COMPLETED
Conditions: High Altitude Pulmonary Hypertension|Sleep
Interventions: PROCEDURE: Nocturnal rest (sleep study)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Interferential Current and Therapeutic Exercise Program in Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Interferential Current and Therapeutic Exercise Program|OTHER: Therapeutic Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy, Radiation Therapy and Surgery in Treating Patients With Cancer of the Esophagus
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: cisplatin|DRUG: paclitaxel|PROCEDURE: surgical procedure|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Absence of Residual Vein Thrombosis Permits to Withdrawn Oral Anticoagulants
Status: COMPLETED
Conditions: Deep Vein Thrombosis
Interventions: DRUG: warfarin accordingly INR value
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examination of Pirfenidone (Esbriet®) Therapy in Coal Workers' Pneumoconiosis With Pulmonary Fibrosis
Status: COMPLETED
Conditions: Coal Workers' Pneumoconiosis (Complicated)
Interventions: DRUG: Pirfenidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adrenocorticotropic Hormone (ACTH) Treatment of Nephrotic Range Proteinuria in Diabetic Nephropathy (NRDN)
Status: COMPLETED
Conditions: Diabetic Nephropathy|Nephrotic Syndrome
Interventions: DRUG: ACTH|DRUG: ACTH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-term Safety Extension Study of Delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD) in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Spasticity
Interventions: DRUG: GW-1000-02
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of an Investigational Influenza (H1N1 Influenza Virus) Vaccine in Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GSK2340272A|BIOLOGICAL: GSK2340269A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Genetic Determinants of the Hypokalemic and Hyperglycemic Effect of Albuterol Inhalation
Status: UNKNOWN
Conditions: Hyperkalemia|Chronic Renal Failure
Interventions: DRUG: Albuterol (1,200 μg) through metered-dose inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-omics Study on the Pathogenesis of Malignant Transformation of Adenomyosis
Status: UNKNOWN
Conditions: Adenomyosis|Endometrial Cancer|Ectopic Endometrial Tissue|Eutopic Endometrium|Genomics|Transcriptomics
Interventions: GENETIC: whole exome sequencing and RNA-sequencing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Relative Bioavailability Study
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PD-0332991|DRUG: PD-0332991|DRUG: PD-0332991|DRUG: PD-0332991
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Of Ranpirnase(Onconase®) To Pemetrexed Plus Carboplatin In Patients With Non-Squamous Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Ranpirnase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Quetiapine XR on Cognition, Mood and Anxiety Symptoms in SSRI-Resistant Unipolar Depression
Status: COMPLETED
Conditions: Unipolar Depression
Interventions: DRUG: Quetiapine XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacokinetic (PK) Comparability of 2 Fixed Subcutaneous (SC) Doses of Aducanumab (BIIB037) With a Single, Weight-Based Intravenous (IV) Dose in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: BIOLOGICAL: Aducanumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resectoscopic Treatment of Atypical Endometrial Polyps in Fertile Women
Status: COMPLETED
Conditions: Atypical Endometrial Polyps|Atypical Endometrial Hyperplasia
Interventions: DEVICE: Levonorgestrel intrauterine device (IUD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risankizumab Versus Secukinumab for Participants With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: risankizumab|DRUG: secukinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Niraparib in Platinum-Sensitive Castration-Resistant Prostate Cancer With DNA Repair Defects
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Adenocarcinoma
Interventions: DRUG: Niraparib Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Food Supplement on Cognitive and Neuropsychological Functioning in Older Adults.
Status: COMPLETED
Conditions: Cognitive Decline|Neurophysiologic Abnormality
Interventions: DIETARY_SUPPLEMENT: Vitis vinifera extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Topo-Pachymetric Customized Accelerated Epi-On Vs Accelerated Epi-Off Corneal Cross Linking in Keratoconus Management
Status: NOT_YET_RECRUITING
Conditions: Amount of Corneal Flattening (Kmax Flattening)|Change in the Endothelial Cell Count
Interventions: PROCEDURE: Corneal cross linking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TMS as a Tool for the Evaluation of Neuromodulatory Effects of Transcutaneous Vagus Nerve Stimulation
Status: COMPLETED
Conditions: Epilepsy
Interventions: PROCEDURE: actual tVNS|PROCEDURE: sham tVNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A mGlu2/3 Agonist in the Treatment of PTSD
Status: TERMINATED
Conditions: Post-traumatic Stress Disorder
Interventions: DRUG: Pomaglumetad Methionil 160mg|DRUG: Pomaglumetad Methionil 40mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Clinical Activity of HCV-796 in Treatment-Naive and Non-Responder Subjects
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Peg-Intron|DRUG: REBETOL|DRUG: HCV 796|DRUG: Peg-Intron|DRUG: REBETOL|DRUG: HCV 796|DRUG: Peg-Intron|DRUG: REBETOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Investigating Safety, Pharmacokinetics and Pharmacodynamics of Concizumab Administered Subcutaneously to Haemophilia A Subjects
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A
Interventions: DRUG: Concizumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Cerebral Protection With Filters vs. Flow Reversal on Cerebral Embolization After Carotid Artery Stenting
Status: TERMINATED
Conditions: Carotid Artery Disease|Stroke
Interventions: PROCEDURE: Carotid filter|PROCEDURE: Carotid reversal of flow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Lidocaine to Reduce Propofol Consumption During Gastroscopy.
Status: COMPLETED
Conditions: Diagnostic Gastroscopy
Interventions: DRUG: Lidocaine 2% Injectable Solution|DRUG: Saline administration as placebo|DRUG: Propofol injection|PROCEDURE: gastroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Atrioventricular Junction Ablation and Biventricular Pacing for Atrial Fibrillation and Heart Failure
Status: UNKNOWN
Conditions: Permanent Atrial Fibrillation
Interventions: PROCEDURE: AV junction ablation|DEVICE: CRT|DRUG: Optimized drug therapy|DEVICE: ICD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of ARQ 621 in Adult Patients With Metastatic Solid Tumors and Hematologic Malignancies
Status: COMPLETED
Conditions: Metastatic Solid Tumors, Refractory/Relapsed Hematologic Malignancies
Interventions: DRUG: ARQ 621
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT