pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Lateral Suspension Versus Sacral Colpopexy POP
Status: NOT_YET_RECRUITING
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Laparoscopic repair of anterior and apical pelvic organ prolapse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Zonisamide in Early Parkinson Disease
Status: WITHDRAWN
Conditions: Parkinson Disease
Interventions: DRUG: Zonisamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised Trial With Irinotecan, Cetuximab and Everolimus (ICE)Compared to Capecitabine and Oxaliplatin (CapOx) for Patients With Gemcitabin Resistant Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: Everolimus, Cetuximab, Irinotecan|DRUG: Capecitabine, Oxaliplatine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kneeling Posture With a Kneeling Stool During Cardiopulmonary Resuscitation in Hospital
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: DEVICE: Chest compression with a step stool|DEVICE: Chest compression with a kneeling stool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dialysis Catheter Placement in Patients With Thoracic Central Venous Occlusion
Status: COMPLETED
Conditions: Central Venous Catheter Thrombosis
Interventions: PROCEDURE: inside-out-access technique with inside-out access device (Surfacer (R))|PROCEDURE: access technique including Sharp recanalization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Guided Written Disclosure Protocol on Psychological Distress and Positive Functioning in Persons With Skin Diseases: a Randomized-controlled Trial
Status: COMPLETED
Conditions: Psychological Distress|Emotional Stress|Skin Diseases|Disclosure
Interventions: BEHAVIORAL: Guided Written Disclosure Protocol Group|BEHAVIORAL: Active Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate Safety/Efficacy of a Single Preop Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery
Status: COMPLETED
Conditions: Post-surgical Pain
Interventions: DRUG: AYX1 Injection 660 mg/6 mL|DRUG: Placebo Injection 6 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Valsalva Assist Device to Treat SVT
Status: COMPLETED
Conditions: SVT|Vagal Bradycardia|Emergencies
Interventions: OTHER: Standard Care|DEVICE: Valsalva Assist Device (VAD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ovarian Reserve Following Bilateral Salpingectomy Versus Tubal Ligation During Cesarean Section
Status: UNKNOWN
Conditions: Ovarian Reserve
Interventions: PROCEDURE: Bilateral salpingectomy|PROCEDURE: Tubal ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib, Bortezomib and Rituximab-CHOP for the Treatment of Elderly Patients With CD20+ DLBCL, IPI ≥ 2
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Ibrutinib and Bortezomib + R-CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Study the Effect of Vytorin on Intracellular Lipid and Inflammation in Obese Subjects
Status: COMPLETED
Conditions: Inflammation
Interventions: DRUG: Vytorin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Palliative Treatment With Liposomal Doxorubicin Plus Cisplatin for Patients With Malignant Pleural Mesothelioma
Status: UNKNOWN
Conditions: Malignant Pleural Mesothelioma
Interventions: DRUG: Liposomal doxorubicin|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment With Metformin in Chinese Children With Alport Syndrome
Status: NOT_YET_RECRUITING
Conditions: Alport Syndrome|Metformin
Interventions: DRUG: Metformin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metformin to Augment Strength Training Effective Response in Seniors (MASTERS)
Status: COMPLETED
Conditions: Aging
Interventions: BEHAVIORAL: Progressive Resistance Training|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevention of Menstrual Migraines: Using Frovatriptan or Placebo During Hormone Free Intervals
Status: COMPLETED
Conditions: Migraines|Bleeding|Spotting
Interventions: DRUG: frovatriptan|DRUG: frovatriptan|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Myofascial Chain Release Techniques on Shoulder Joint Range of Motion in Breast Cancer Survivors
Status: RECRUITING
Conditions: Breast Cancer Survivors
Interventions: OTHER: conventional physiotherapy|OTHER: Manual lymphatic drainage|OTHER: Myofascial relasing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aciclovir Versus Placebo for HSV-2 Meningitis
Status: NOT_YET_RECRUITING
Conditions: Herpes Simplex 2|Meningitis, Viral
Interventions: DRUG: Acyclovir 50 MG/ML|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patients' Quality of Life After Pilonidal Cyst Operations.
Status: ENROLLING_BY_INVITATION
Conditions: Pilonidal Cyst|Pain Postoperative|Quality of Life
Interventions: PROCEDURE: Minimally invasive pit-picking surgery|PROCEDURE: Radical surgical excision without suturing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of CR011-vcMMAE in Subjects With Unresectable Stage III or Stage IV Melanoma
Status: COMPLETED
Conditions: Unresectable Stage III or Stage IV Melanoma
Interventions: DRUG: CR011-vcMMAE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Varenicline for Smoking Cessation in Heavy Drinking Smokers
Status: COMPLETED
Conditions: Nicotine Dependence|Smoking|Heavy Drinking
Interventions: DRUG: Extended Varenicline Pretreatment|DRUG: Short-term Varenicline Pretreatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exacerbation Study
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Indacaterol 150 µg|DRUG: Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Infusion on Intraoperative Propofol,Fentanyl Requirements in Spine Surgery for Pediatric Cancer Patients
Status: UNKNOWN
Conditions: Spine Cancer|Anesthesia
Interventions: DRUG: Precedex Injectable Product|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: AVE7688 in Patients With Mild to Moderate Blood Pressure
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: AVE7688|DRUG: Losartan-potassium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Irinotecan HCI for Recurrent Anaplastic Astrocytomas, Mixed Malignant Gliomas, and Oligodendrogliomas
Status: TERMINATED
Conditions: Astrocytoma|Glioma|Oligodendroglioma
Interventions: DRUG: Irinotecan Hydrochloride (HCI) Treatment|DRUG: Continued Irinotecan Hydrochloride (HCI) Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: EEG as Predictor of HD-tDCS Effectiveness in Long COVID-19
Status: UNKNOWN
Conditions: Coronavirus COVID-19|Respiratory Infection
Interventions: DEVICE: Experimental group|DEVICE: Sham Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Risk-ADAPTed Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation|Allogeneic Stem Cell Transplantation|Hematologic Malignancies
Interventions: DRUG: Fludarabine|DRUG: Melphalan|RADIATION: Total Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD19-CART in the Treatment of R/R CD19 Positive Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Non Hodgkin Lymphoma
Interventions: BIOLOGICAL: CD19 CAR-T cells infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiemetic Prophylaxis for Postdischarge Nausea and Vomiting After Hip Arthroscopy
Status: COMPLETED
Conditions: Nausea and Vomiting, Postoperative
Interventions: DRUG: Ondansetron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of 3D Anal Fistula Models on Patient Understanding and Decision Making
Status: COMPLETED
Conditions: Fistula in Ano|Ano Fistula
Interventions: OTHER: Explanation with 3D printed fistula model|OTHER: Standard explanation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Observational Prospective Study on Patients Treated With Norditropin®
Status: COMPLETED
Conditions: Growth Hormone Disorder|Growth Hormone Deficiency in Children|Adult Growth Hormone Deficiency|Genetic Disorder|Turner Syndrome|Foetal Growth Problem|Small for Gestational Age|Chronic Kidney Disease|Chronic Renal Insufficiency|Noonan Syndrome
Interventions: DRUG: somatropin|DRUG: somatropin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of the Extracorporeal Liver Assist Device (ELAD®) In Patients With Fulminant Hepatic Failure (FHF)
Status: WITHDRAWN
Conditions: Fulminant Hepatic Failure
Interventions: OTHER: Standard of Care|DEVICE: ELAD®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biliary Cannulation During Endoscopic Retrograde Cholangiopancreatography: Precut Versus Conventional Cannulation
Status: COMPLETED
Conditions: Jaundice, Obstructive
Interventions: PROCEDURE: conventional ERCP|PROCEDURE: Precut ERCP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Laser Therapy Prevents Mucositis Oral in Chemotherapy for Bone Marrow Transplantation?
Status: UNKNOWN
Conditions: Oral Mucositis|Effects of Chemotherapy|Malignant Neoplasm of Bone Marrow
Interventions: DEVICE: Low level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PK Comparisons of Bepotastine Besilate 10 mg and Bepotastine Salicylate 9.64 mg
Status: COMPLETED
Conditions: Allergic Rhinitis|Urticaria|Pruritus
Interventions: DRUG: Test-Bepotastine salicylate 9.64 mg|DRUG: Reference-bepotastine besilate 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of the Effect of tDCS on Cannabis Craving
Status: UNKNOWN
Conditions: Addiction to Cannabis
Interventions: OTHER: Neuromodulation by tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate and Compare the Efficacy and Pharmacokinetics of MK-0873 for the Treatment of Plaque Psoriasis (MK-0873-022)
Status: COMPLETED
Conditions: Psoriasis|Plaque Psoriasis
Interventions: DRUG: MK-0873 2% Cream|DRUG: MK-0873 vehicle (placebo) Cream|DRUG: Calcitriol Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Treatment Versus Expectant Management of PDA in Preterm Infants
Status: COMPLETED
Conditions: Patent Ductus Arteriosus
Interventions: DRUG: Ibuprofen|DRUG: Paracetamol|OTHER: Expectant Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Umbilical Cord Mesenchymal Stem Cells for the Treatment of Severe Viral Pneumonian
Status: UNKNOWN
Conditions: Severe Pneumonia
Interventions: BIOLOGICAL: Human umbilical cord mesenchymal stem cells|PROCEDURE: Routine treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Measuring the Impact of Dietary Supplementation With a New Baking Product on Gut Microbiota and Cholesterol Metabolism
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: PreBIOil|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: CD19 CAR and PD-1 Knockout Engineered T Cells for CD19 Positive Malignant B-cell Derived Leukemia and Lymphoma
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia|Burkitt Lymphoma
Interventions: BIOLOGICAL: CD19 CAR and PD-1 knock out engineered T-cells|BIOLOGICAL: CD19 CAR T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Efficacy of SelK2 to Prevent Blood Clots in Patients Undergoing Total Knee Replacement
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: SelK2|BIOLOGICAL: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Upper Third Molar Extraction on Distalization Carriere Motion Appliance :A Prospective Clinical Study
Status: UNKNOWN
Conditions: Class II Malocclusion
Interventions: DEVICE: carriere motion appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.
Status: RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: [177Lu]Lu-DOTA-TATE|DRUG: [68Ga]Ga-DOTA-TATE|OTHER: Temozolomide|OTHER: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Epigenetic Age on Clinic-biological Presentation and Prognosis in Myeloproliferative Neoplasms Epigenetic Age in Myeloproliferative Neoplasms (EpiC)
Status: RECRUITING
Conditions: Myeloproliferative Neoplasm
Interventions: BIOLOGICAL: Assessment of the epigenetic age
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cumulative Pregnancy Rate With Lower and Higher Gonadotropin Dose During IVF Among Poor Responders
Status: UNKNOWN
Conditions: Infertility|Ovarian Dysfunction
Interventions: DRUG: Follitropin Alfa|DRUG: Follitropin delta|DRUG: human menopausal gonadotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Exercises to Improve Leg Function After Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries|Paraplegia|Paraparesis
Interventions: DEVICE: Robotic body weight supported treadmill training|OTHER: Harness-supported multimodal balance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PTFE Covered Stents Versus Naked Stents in the TIPS (Transjugular Intra-hepatic Porto-systemic Shunt)
Status: COMPLETED
Conditions: Cirrhotic Portal Hypertension
Interventions: DEVICE: Naked Stents: Wallstent® (Boston Scientific), Luminexx® (Bard), Zilver® (Cook), Palmaz Genesis® and Smart Control® (Cordis)|DEVICE: PTFE Covered Stents: Fluency® (Bard), Advanta V12® (Atrium) and Viatorr® (Gore)|PROCEDURE: Transjugular intrahepatic portosystemic shunt (TIPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Applying PET/MR in Neuroendocrine Tumors - Imaging Dynamic Processes in Both Modalities
Status: UNKNOWN
Conditions: Neuroendocrine Tumors
Interventions: DIAGNOSTIC_TEST: PET/MR scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: In and ex Vivo Mitochondrial Function of the Heart
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Diabetic Cardiomyopathies
Interventions: DIAGNOSTIC_TEST: 31P-MRS scan and cardiac MRI scan|DIAGNOSTIC_TEST: Atrial biopsy for high-resolution respirometry|DIAGNOSTIC_TEST: Blood analysis|DIAGNOSTIC_TEST: Body composition|DIAGNOSTIC_TEST: Indirect Calorimetry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Method of Assessment of Driving Ability in Patients Suffering From Wakefulness Pathologies.
Status: COMPLETED
Conditions: Cirrhosis
Interventions: DRUG: L-carnitine|DRUG: Lactulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: AIMSPRO in Established Diffuse Cutaneous Systemic Sclerosis
Status: UNKNOWN
Conditions: Systemic Sclerosis
Interventions: DRUG: Hyperimmune caprine serum|DRUG: Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Heart Rate Variability in Response to Metformin Challenge
Status: COMPLETED
Conditions: Fibromyalgia|Mitochondrial Diseases|Movement Disorders|Diabetes Mellitus, Type 2
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Sitagliptin on Polycystic Ovarian Syndrome Patients
Status: NOT_YET_RECRUITING
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Sitagliptin 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Symptomatic Remission in Schizophrenia With Long Acting Risperidone Microspheres
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AZD2171 in Treating Patients With Recurrent Ovarian, Peritoneal, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Primary Peritoneal Serous Adenocarcinoma|Recurrent Ovarian Epithelial Cancer|Stage I Ovarian Epithelial Cancer|Stage II Ovarian Epithelial Cancer
Interventions: DRUG: cediranib maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding and Overcoming the Racial/Ethnic Inequalities in COVID-19 Vaccination Acceptance
Status: COMPLETED
Conditions: Vaccine Refusal
Interventions: BEHAVIORAL: Trust boost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemolysis During Pulsed-field and Radiofrequency Ablation
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Hemolysis|Pulsed-field Ablation
Interventions: DEVICE: Pulsed-field ablation|DEVICE: Radiofrequency ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exploring Occupancy of Dopamine D3 Receptor by Buspirone in Humans Using PET
Status: COMPLETED
Conditions: Smoking Cessation|Tobacco Use Cessation
Interventions: DRUG: Buspirone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Beta Glucan's Effect on Pembrolizumab Immunologic Response in Stage III-IV Melanoma
Status: RECRUITING
Conditions: Melanoma Stage III|Melanoma Stage IV
Interventions: DIETARY_SUPPLEMENT: Beta-Glucan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of a Vaginal Pessary (pHyph) in Vulvovaginal Candidiasis
Status: COMPLETED
Conditions: Vulvovaginal Candidiasis
Interventions: DEVICE: pHyph, Gedea pessary
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Pharmacokinetics and Efficacy of Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) in Previously Treated Subjects With Severe Hemophilia A
Status: COMPLETED
Conditions: Severe Hemophilia A
Interventions: DRUG: Factor VIII (rFVIIIFc)|DRUG: Advate®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of HSD3B1 (1245C) Gene Mutation on Treatment of Stage I-III Breast Cancer
Status: RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Breast Adenocarcinoma|Invasive Breast Carcinoma of No Special Type
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Letrozole|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LEICeSter Tendon Extracorporeal Shockwave Studies
Status: RECRUITING
Conditions: Tendinopathy
Interventions: DEVICE: Extra-Corporeal Shockwave Therapy (ESWT)|OTHER: structured rehabilitation programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: E-cigarettes, Nicotine Inhaler, and Blood Vessel Function
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: OTHER: e-cig with nicotine|OTHER: e-cig without nicotine|OTHER: nicotine inhaler|OTHER: sham control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Tolerability, Safety, and PK Characteristics of SIM1910-09 in Healthy Chinese Volunteers
Status: COMPLETED
Conditions: Acute Ischemic Stroke|Cerebral Edema
Interventions: DRUG: SIM1910-09|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relapsed Malignant Blood Cancer After Allogeneic Hematopoietic Stem Cell Transplantation
Status: TERMINATED
Conditions: Chronic Myelogenous Leukemia|Acute Myelogenous Leukemia|Acute Lymphoblastic Leukemia|Hodgkins Lymphoma|Non-Hodgkins Lymphoma
Interventions: BIOLOGICAL: Allogeneic stem cell transplant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Expanded Treatment Protocol (ETP) of Midostaurin (PKC412) in Patients 18 Years of Age or Older With Newly-diagnosed FLT3-mutated Acute Myeloid Leukemia (AML)
Status: NO_LONGER_AVAILABLE
Conditions: FLT3-mutated Acute Myeloid Leukemia
Interventions: DRUG: Midostaurin
Study Type: EXPANDED_ACCESS
Clinical trial: Potential Impact of Polycystic Ovarian Syndrome on Protein Modifications and Accumulation
Status: COMPLETED
Conditions: Polycystic Ovarian Syndrome (PCOS)|Insulin Resistance|Overweight|Obese
Interventions: BEHAVIORAL: Aerobic Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Remote Delivered Lifestyle Therapeutics Program
Status: COMPLETED
Conditions: Body Weight Changes|Weight Loss|Healthy Diet|Obesity
Interventions: BEHAVIORAL: Video Conferencing Health Coaching with devices|BEHAVIORAL: Video Conferencing Health Coaching with no devices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of AMG 570 in Subjects With Active Systemic Lupus Erythematosus (SLE)
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus (SLE)
Interventions: DRUG: Rozibafusp Alfa|DRUG: Placebo for Rozibafusp Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study Evaluating NTX100 Neuromodulation System for Medication-Refractory Primary RLS
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DEVICE: NTX100 Neuromodulation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kappa Opioid Receptor Antagonism for the Tx of AUD and Comorbid PTSD
Status: TERMINATED
Conditions: Post Traumatic Stress Disorder|Alcohol Abuse
Interventions: DRUG: 2mg Buprenex and 380mg Vivitrol|DRUG: Placebo (SL pill qd, IM injection q4weeks)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Pharmacological and Electric Modulation of NMDA Pathway on the Cognitive Flexibility and Volitional Movement Preparation in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease With Dementia
Interventions: DIETARY_SUPPLEMENT: Sarcosine Capsule|DIETARY_SUPPLEMENT: Placebo Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Explore the Therapeutic Effect of Eluxadoline in Treating Irritable Bowel Syndrome With Diarrhea in Children
Status: RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Eluxadoline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transversalis Fascia Plane Block in Pediatric Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain, Postoperative|Regional Anesthesia|Parental Satisfaction
Interventions: PROCEDURE: Transversalis Fascia Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ultraviolet B (UVB) Light Therapy in the Treatment of Skin Conditions With Altered Dermal Matrix
Status: COMPLETED
Conditions: Keloid|Scleroderma, Localized|Acne Keloidalis|Scars|Granuloma Annulare
Interventions: PROCEDURE: UVB Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combined Effects of mHealth Psychoeducational and Benson Relaxation Technique Among Female Informal Caregivers of Cancer Patients in Bangladesh
Status: NOT_YET_RECRUITING
Conditions: Caregiver Burden
Interventions: OTHER: Benson relaxation technique and mHealth psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Randomized, Placebo-Controlled Trial to Examine the Efficacy of Oral Donepezil in Subjects With MCI
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: donezepil (Aricept)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Methylene Blue Spray for Identification of Recurrent Laryngeal Nerve and Parathyroid Gland
Status: COMPLETED
Conditions: Methylene Blue|Recurrent Laryngeal Nerve Injuries|Parathyroid Gland
Interventions: DIAGNOSTIC_TEST: methylene blue identification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Analysis of Clinical Effect of Subanesthetic Dose of Esketamine Combined With Hip Capsule Peripheral Nerve Block in Elderly Patients Undergoing Total Hip Arthroplasty
Status: COMPLETED
Conditions: Total Hip Arthroplasty
Interventions: DRUG: esketamine sub-anesthetic,|DRUG: esketamine sub-anesthetic|DRUG: esketamine sub-anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OASIS-6 : The Safety and Efficacy of Fondaparinux Versus Control Therapy in Patients With ST Segment Elevation Acute Myocardial Infarction
Status: COMPLETED
Conditions: Thromboembolism
Interventions: DRUG: fondaparinux - UFH not indicated|OTHER: Control - UFH not indicated|DRUG: Fondaparinux - UFH indicated|DRUG: Control - UFH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysing the Effect of Empagliflozin on Reduction of Tissue Sodium Content in Patients With Chronic Heart Failure
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: DRUG: Empagliflozin 10mg|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Exercise Therapy Protocols in Patients With Bruxism
Status: RECRUITING
Conditions: Bruxism
Interventions: OTHER: Mandibular Exercise|OTHER: Mandibular Exercise and Postural Exercise Group|OTHER: Occlusal Splint Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study to Investigate Safety and Tolerability of Shorter Infusion of Fabrazyme
Status: RECRUITING
Conditions: Fabry's Disease
Interventions: DRUG: AGALSIDASE BETA (GZ419828)|DRUG: Acetaminophen|DRUG: Diphenhydramine|DRUG: Dexamethasone|DRUG: Montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Expanded Access Study of Abiraterone Acetate in Patients With Advanced Prostate Cancer Who Have Completed Clinical Study COU-AA-001
Status: COMPLETED
Conditions: Prostate Neoplasms
Interventions: DRUG: Abiraterone acetate|DRUG: Glucocorticoid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Boceprevir and Telaprevir on Dolutegravir Pharmacokinetics in Healthy Adult Subjects (ING115697).
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: DTG|DRUG: BCV|DRUG: TVR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study To Evaluate The Efficacy, Safety, Pharmacokinetics, And Pharmacodynamics Of Satralizumab In Participants With Thyroid Eye Disease (SatraGO-2)
Status: RECRUITING
Conditions: Thyroid Eye Disease
Interventions: DRUG: Satralizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML
Status: RECRUITING
Conditions: AML, Childhood|Aml|Acute Myeloid Leukemia, Pediatric|Acute Myeloid Leukemia
Interventions: DRUG: Rabbit Anti thymocyte globulin|DRUG: Busulfan|DRUG: Fludarabine|DRUG: Thiotepa|DRUG: Melphalan|BIOLOGICAL: TCR alpha beta / CD19+ depleted haploidentical hematopoietic progenitor cell graft|BIOLOGICAL: memory-like natural killer cells|BIOLOGICAL: IL-2|DRUG: Plerixafor|BIOLOGICAL: Granulocyte Colony-Stimulating Factor|DEVICE: CliniMACS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a Nutrition Screening Tool
Status: COMPLETED
Conditions: Adenocarcinoma of the Gastroesophageal Junction|Cervical Cancer|Endometrial Cancer|Esophageal Cancer|Fallopian Tube Cancer|Gastric Cancer|Ovarian Cancer|Sarcoma|Vaginal Cancer|Vulvar Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Effectiveness of Spa Treatment in Swieradow Zdroj With Special Regard to the Action of Radon Waters
Status: COMPLETED
Conditions: Osteoarthritis|Degenerative Disc Disease
Interventions: RADIATION: Radon therapeutic baths and inhalations|PROCEDURE: Kinesiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Tolerability of AMG 986 in Healthy Volunteers and Heart Failure Patients
Status: TERMINATED
Conditions: Heart Failure|Healthy Volunteer
Interventions: DRUG: AMG 986 IV|DRUG: AMG 986 PO|DRUG: Placebo PO|DRUG: Placebo IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Diet on the Microbiota / Endoccanabinoidome Axis in Response to Physical Activity
Status: COMPLETED
Conditions: Diet Habit|Microbial Colonization|Activity, Motor
Interventions: OTHER: 3 maximal aerobic tests
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of the Efficacy and Safety of Risankizumab in Participants With Moderately to Severely Active Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: placebo for risankizumab|DRUG: risankizumab IV|DRUG: risankizumab SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Protocol: Phytomedicine-AMARGOL®, Clinical Trial for Efficacy Proof on Therapeutics
Status: COMPLETED
Conditions: Digestive System Disorders
Interventions: DRUG: AMARGOL®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Alpha Lipoic Acid on Clinical and Electrophysiological Recovery in Carpal Tunnel Syndrome Undergoing Surgical Release
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: alpha lipoic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Comparison of the Efficacy of Once and Twice Daily Colchicine Dosage in Pediatric Patients With FMF
Status: COMPLETED
Conditions: Familial Mediterranean Fever
Interventions: DRUG: colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Automatic External Defibrillation Monitoring in Cardiac Arrest
Status: COMPLETED
Conditions: Death, Sudden, Cardiac|Ventricular Fibrillation|Tachycardia, Ventricular
Interventions: DEVICE: Defibrillation of pulseless VT/VF by AECD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Usability of the Neuro-trigger Artificial Eye Blinking Stimulation Device in Patients With Paralysis of the Facial Nerve.
Status: RECRUITING
Conditions: Paralysis|Paralysis; Eye|Paralysis; Bell
Interventions: DEVICE: Neurotrigger Basic. eye blinking stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EURopean Trial In Atrial Fibrillation(AF) or Flutter (AFL) Patients Receiving Dronedarone for the maIntenance of Sinus Rhythm (EURIDIS)
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DRUG: Dronedarone (SR33589)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Transdiagnostic, Self-guided Internet Intervention ("Velibra") for Waitlist Patients With Anxiety Disorders
Status: RECRUITING
Conditions: Panic Disorder With Agoraphobia|Panic Disorder Without Agoraphobia|Generalized Anxiety Disorder|Social Anxiety Disorder
Interventions: BEHAVIORAL: Velibra
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Assess the Safety and Pharmacokinetics of SRT2379 in Normal Healthy Male Volunteers
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: SRT2379|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Non-invasive Acupuncture-like Transcutaneous Electrical Nerve Stimulation (Altens) to Help Alleviate Xerostomia After Radiation Therapy for Cancers of the Head and Neck
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: RADIATION: Acupuncture-Like Transcutaneous Electrical Stimulation (ALTENS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Pharmacokinetic Study With Multiple Ascending Doses of ORM-12741
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ORM-12741|DRUG: Placebo for ORM-12741
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AFRICA: Atorvastatin Plus Fenofibric Acid (TriLipix) in the Reduction of Intermediate Coronary Atherosclerosis
Status: TERMINATED
Conditions: Coronary Atherosclerosis
Interventions: DRUG: Placebo|DRUG: TriLipix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Multidisciplinary Approach to Breast Cancer Through the Study of Altered Transcriptomic and Immune Accompanied by the Identification of Extractable Markers From the Radiodiagnostic Bioimaging
Status: RECRUITING
Conditions: Breast Cancer Patients
Interventions: OTHER: surgery for breast cancer and imaging test evaluations
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of CM310 in Subjects With Moderate to Severe Asthma
Status: RECRUITING
Conditions: Moderate to Severe Asthma
Interventions: DRUG: CM310|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare Anti-inflammatory Dentifrices
Status: COMPLETED
Conditions: Gingivitis
Interventions: DRUG: Triclosan/Copolymer/fluoride toothpaste|DRUG: Sodium monofluorophosphate toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Erector Spina Plan Block Application Time on Postoperative Anxiety
Status: UNKNOWN
Conditions: Recovery of Postoperative
Interventions: OTHER: preoperative erector spina plane block|OTHER: intraoperative erector spina plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Randomized Controlled Open Label Trial to Assess the Safety and Efficacy of the OptiVein IV Catheter in an Oncologic Population
Status: TERMINATED
Conditions: Intravenous Injections
Interventions: DEVICE: Insertion of OptiVein IV catheter|DEVICE: Insertion of Vasofix Certo IV catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cardiac Magnetic Resonance for Asymptomatic Type 2 Diabetics With Cardiovascular High Risk (CATCH) - Pilot Study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: Cardiac Magnetic Resonance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intravitreal Aflibercept Injection for Symptomatic Macular Edema From Retinal Artery Macroaneurysms
Status: UNKNOWN
Conditions: Macular Edema|Retinal Artery Macroaneurysm
Interventions: DRUG: aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum
Status: RECRUITING
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: Bictegravir (BIC)|DRUG: Tenofovir alafenamide (TAF)|DRUG: Cabotegravir (CAB)|DRUG: Dolutegravir (DTG)|DRUG: Atazanavir/ritonavir (ATV/r)|DRUG: Darunavir/ritonavir (DRV/r)|DRUG: Lopinavir/ritonavir (LPV/r)|DRUG: Cobicistat|DRUG: Ritonavir|DRUG: First-Line TB Treatment|DRUG: Second-Line TB Treatment|DRUG: Doravirine (DOR)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Predictive Value of Combining AccuIMR and AccuFFR in Patients With STEMI
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute ST Segment Elevation Myocardial Infarction|Prognosis
Interventions: DIAGNOSTIC_TEST: AccuIMR and AccuFFR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Lifestyle Education About Nutrition for Diabetes (Legend) Study
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Very low-carbohydrate diet|BEHAVIORAL: Moderate-carbohydrate plate-method diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Letrozole and Imatinib Mesylate in Treating Postmenopausal Participants With Estrogen or Progesterone Positive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Estrogen Receptor Positive|KIT Positive|PDGFR Positive|Postmenopausal|Progesterone Receptor Positive|Prognostic Stage IV Breast Cancer AJCC v8
Interventions: DRUG: Imatinib Mesylate|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mirena® ± Metformin as Fertility-preserving Treatment for Young Asian Women With Early Endometrial Cancer
Status: UNKNOWN
Conditions: Endometrial Cancer
Interventions: DRUG: Metformin|DEVICE: Mirena®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABT-450/Ritonavir/ ABT-267 (ABT-450/r/ABT-267) and ABT-333 Co-Administered With Ribavirin (RBV) in Treatment Naïve and Treatment Experienced Asian Adults With Genotype 1b Chronic Hepatitis C Virus (HCV) Infection and Compensated Cirrhosis
Status: COMPLETED
Conditions: Chronic Hepatitis C Virus (HCV)
Interventions: DRUG: ABT-450/r/ABT-267|DRUG: ABT-333|DRUG: ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decitabine Combined With Gemcitabine in First-line Treatment of AdvancedPancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: Decitabine|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of EEG- Microstate Neurofeedback on Attention and Impulsivity in Adult Attention-deficit/Hyperactivity Disorder (ADHD) and Neurotypical Controls
Status: RECRUITING
Conditions: ADHD|Healthy
Interventions: DEVICE: Neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE