pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: HIV, Buprenorphine, and the Criminal Justice System
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|Acquired Immunodeficiency Syndrome|Opiate Addiction|Drug Dependence
Interventions: DRUG: Buprenorphine/naloxone|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Hemorrhoidoplasty Versus Open Surgical Hemorrhoidectomy in Second and Third Degree Piles
Status: NOT_YET_RECRUITING
Conditions: Hemorrhoids
Interventions: PROCEDURE: laser hemorrhoidoplasty|PROCEDURE: open surgical hemorrhoidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRecision Interventions for SMoking in the SCCS
Status: COMPLETED
Conditions: Tobacco Use Cessation
Interventions: DRUG: Nicotine patch|DRUG: Varenicline|GENETIC: Nicotine metabolism|GENETIC: Genetically-informed lung cancer risk score|BEHAVIORAL: NCI "Clearing the Air"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Study of Dronabinol and BRENDA for the Treatment of Cannabis Withdrawal
Status: COMPLETED
Conditions: Marijuana Dependence
Interventions: DRUG: Dronabinol|BEHAVIORAL: BRENDA therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bispectral Index and Emergence Agitation in Spinal Surgeries
Status: RECRUITING
Conditions: Anesthesia Recovery Periods|Anesthesia Complication|Electroencephalography
Interventions: OTHER: In the study, bispectral index monitoring and follow-up will be applied to both groups.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stand-alone Totally Thoracoscopic Left Atrial Appendage Occlusion Using AtriClip® Device in Non-valvular Atrial Fibrillation.
Status: RECRUITING
Conditions: Stroke Prevention|Atrial Fibrillation|Safety Issues
Interventions: DEVICE: AtriClip™ LAA Exclusion System|DRUG: Oral anticoagulation therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ribavirin for Patients With Recurrent/Metastatic (R/M) Human Papillomavirus (HPV)-Related Malignancies
Status: COMPLETED
Conditions: Human Papillomavirus (HPV)-Related Malignancies|Recurrent/Metastatic (R/M) Human Papillomavirus (HPV)-Related Malignancies
Interventions: DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Dense Temozolomide + Lapatinib for Recurrent Ependymoma
Status: COMPLETED
Conditions: Brain Tumors|Spinal Cord Tumors
Interventions: DRUG: Temozolomide|DRUG: Lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Distribution and Dynamic Behavior of TH-SC01 Cells in Vivo in Patients With Perianal Fistula
Status: RECRUITING
Conditions: Anal Fistula|Complex Perianal Fistulas|Crohn's Disease
Interventions: BIOLOGICAL: Mesenchymal Stem Cells (MSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Early Goal Directed Therapy in Colorectal Surgery: a Feasibility Study
Status: COMPLETED
Conditions: Perioperative/Postoperative Complications|C.Surgical Procedure; Digestive System
Interventions: DRUG: Dobutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ramucirumab (LY3009806) in Participants With Advanced Liver Cancer
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: BIOLOGICAL: Ramucirumab|DRUG: FOLFOX4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NKG2D-CAR-NK92 Cells Immunotherapy for Solid Tumors
Status: RECRUITING
Conditions: Relapsed/Refractory Solid Tumors
Interventions: BIOLOGICAL: NKG2D-CAR-NK92 cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerance of Cellularised LG002 Versus Uncellularised LG002 in the Treatment of Severe Burns Injuries
Status: TERMINATED
Conditions: Burns
Interventions: DRUG: Dermal substrate cellularised LG002 (10x10cm)|DEVICE: Dermal substrate uncellularised LG002 (10x10 cm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Mogamulizumab in Advanced-stage, Relapsed/Refractory Cutaneous T-cell Lymphomas
Status: RECRUITING
Conditions: Cutaneous T Cell Lymphoma|Fungoides Mycosis Sezary Syndrome
Interventions: DRUG: Pembrolizumab|DRUG: Mogamulizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiotherapy Versus Conventional Radiotherapy in Medically-Inoperable Non-Small Lung Cancer Patients
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: RADIATION: Stereotactic Body Radiotherapy (SBRT)|RADIATION: Conventional Radiotherapy (CRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Preoperative Long Period Octreotide Combined With Postoperative Short Period Octreotide on the Complications After Pancreatectomy. A Prospective, Multicenter Clinical Trial
Status: UNKNOWN
Conditions: Pancreatic Diseases
Interventions: DRUG: Preoperative Long Period Octreotide Combined With Postoperative Short Period Octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacist-led Intervention to Enhance Medication Adherence in Post-acute Coronary Syndrome Patients in Vietnam
Status: UNKNOWN
Conditions: Acute Coronary Syndrome|Medication Adherence
Interventions: BEHAVIORAL: Pharmacist-delivered multifaceted intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Evaluation of Cardiac Output Estimation Based on Pulse Wave Transit Time
Status: COMPLETED
Conditions: Myocardial Infarction|Myocardial Ischemia
Interventions: DEVICE: Pulmonary Artery Catheter (PAC)|DEVICE: Endotracheal Cardiac Output Monitor (ECOM)|DEVICE: Estimated Continuous Cardiac Output (esCCO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Sacral Neuromodulation With InterStim® Therapy for Intractable Urinary Voiding Dysfunctions (SOUNDS): an Observational Study
Status: COMPLETED
Conditions: Urinary Incontinence|Over Active Bladder|Urinary Retention
Interventions: DEVICE: Sacral Nerve Modulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Chymosin on the Intestinal Absorption of Calcium
Status: COMPLETED
Conditions: Osteoporosis|Osteopenia
Interventions: DIETARY_SUPPLEMENT: Drug A Chymosin|DIETARY_SUPPLEMENT: Drug B: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hyperbaric Oxygen and Orthopedic Comprehensive Treatment for Traumatic Incomplete Spinal Cord Injury in the Plateau
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: PROCEDURE: control group|OTHER: hyperbaric oxygen group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib, Liposomal Doxorubicin Hydrochloride, Dexamethasone, and Cyclophosphamide in Treating Patients With Multiple Myeloma That Relapsed After Autologous Stem Cell Transplant
Status: TERMINATED
Conditions: Refractory Multiple Myeloma
Interventions: DRUG: liposomal doxorubicin|DRUG: bortezomib|DRUG: dexamethasone|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three Good Things (3GT) - Intervention for Transitional Care Patients
Status: TERMINATED
Conditions: Positive Thinking|Psychology, Positive|Resilience, Psychological
Interventions: BEHAVIORAL: Three Good Things (3GT) Positive Psychology journaling activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: pBFS Guided 20min Inter-session Interval rTMS Treatment for MDD
Status: NOT_YET_RECRUITING
Conditions: Moderate Depression|Major Depressive Disorder|Severe Depression
Interventions: DEVICE: active rTMS: 20min inter-session interval|DEVICE: active rTMS: 50min inter-session interval|DEVICE: sham rTMS: 20min inter-session interval|DEVICE: sham rTMS: 50min inter-session interval
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hydration Status Assessment Through Body Composition Monitoring in Patients With Acute Myocardial Infarction
Status: UNKNOWN
Conditions: Dehydration|Acute Myocardial Infarction|Renal Artery Stenosis
Interventions: DEVICE: Body Composition Monitoring|PROCEDURE: Coronarography|PROCEDURE: Primary Percutaneous Coronary Intervention|PROCEDURE: Renal Angiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunogenicity and Safety Study of NBP615 in Healthy Female
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: BIOLOGICAL: NBP615|BIOLOGICAL: Gardasil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: User-centred Assistive System for Arm Functions in Neuromuscular Subjects
Status: COMPLETED
Conditions: Muscular Dystrophies|Muscular Dystrophy, Duchenne|Muscular Dystrophy, Becker|Muscular Dystrophy, Limb-Girdle Type 2
Interventions: DEVICE: Assistive device (Armon Ayura) test|DEVICE: Assistive device (Jaeco Wrex) test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate Efficacy and Safety of BGE-117 in Moderately to Severely Anemic Older Individuals After Major Hip Surgery
Status: WITHDRAWN
Conditions: Acute Posthemorrhagic Anemia
Interventions: DRUG: BGE-117, 4mg|DIETARY_SUPPLEMENT: Ferrous Sulfate|OTHER: Matching Placebo|DRUG: BGE-117, 12mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Ophthalmology Treatment Study II
Status: RECRUITING
Conditions: Retinal Disease|Age-Related Macular Degeneration|Retinitis Pigmentosa|Stargardt Disease|Optic Neuropathy|Nonarteritic Ischemic Optic Neuropathy|Optic Atrophy|Optic Nerve Disease|Glaucoma|Leber Hereditary Optic Neuropathy|Blindness|Vision Loss Night|Vision Loss Partial|Vision, Low|Retinopathy|Maculopathy|Macular Degeneration|Retina Atrophy
Interventions: PROCEDURE: Arm 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transurethral Ventral Wall of Urethra-preserving Enucleation of Prostate
Status: UNKNOWN
Conditions: Benign Prostatic Hyperplasia
Interventions: PROCEDURE: transurethral ventral wall of urethra-preserving enucleation of prostate|PROCEDURE: transurethral prostatic resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of XH-S004 in Healthy Volunteers
Status: NOT_YET_RECRUITING
Conditions: Healthy Adults
Interventions: DRUG: XH-S004 tablet|DRUG: XH-S004 placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of PF-07224826, as a Single Agent or in Combination With Endocrine Therapy in Participants With Breast Cancer and Other Advanced Solid Tumors.
Status: WITHDRAWN
Conditions: Breast Cancer|Ovarian Cancer|Liposarcoma|Non-small Cell Lung Cancer (NSCLC)|Endometrial|Solid Tumors
Interventions: DRUG: PF-07224826|COMBINATION_PRODUCT: Fulvestrant|DRUG: PF-07224826|COMBINATION_PRODUCT: Fulvestrant|DRUG: PF-07224826|COMBINATION_PRODUCT: Fulvestrant|DRUG: PF-07224826|COMBINATION_PRODUCT: Fulvestrant|DRUG: PF-07224826|COMBINATION_PRODUCT: Fulvestrant|DRUG: PF-07224826|COMBINATION_PRODUCT: Fulvestrant|DRUG: PF-07224826|COMBINATION_PRODUCT: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Classification for the Assessment and Grading of Unexpected Events in Pediatric Surgery: The Clavien-Madadi Classification
Status: UNKNOWN
Conditions: Complication of Surgical Procedure|Complication of Anesthesia|Complication,Postoperative|Complication of Medical Care
Interventions: DIAGNOSTIC_TEST: Novel severity grading system of unexpected events in pediatric surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low Pain Prediction in Cesarean Section Patients
Status: TERMINATED
Conditions: Scheduled Cesarean Sections|Postoperative Pain Management|Side Effects
Interventions: DRUG: duramorph|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Safety, Tolerability, Pharmacokinetics and the Food Effect on PK of ASC10 Tablets in Healthy Subjects
Status: COMPLETED
Conditions: SARS CoV 2 Infection
Interventions: DRUG: ASC10|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Observational Study to Characterize Biomarkers and Disease Progression in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome
Status: RECRUITING
Conditions: Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Studying DNA in Samples From Younger Patients With Down Syndrome and Acute Myeloid Leukemia Treated on COG-AAML0431 Clinical Trial
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: gene mapping|GENETIC: microarray analysis|GENETIC: mutation analysis|GENETIC: nucleic acid sequencing|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Discharge and Outpatient Care After Chemotherapy in Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: OTHER: medical chart review|OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Tauroursodeoxycholic Acid for Hepatobiliary Disease in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: tauroursodeoxycholic acid|DRUG: ursodiol
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Therapeutic Exploratory Clinical Study to Evaluate the Antihypertensive Efficacy of Fimasartan (BR-A-657•K) During 24 Hours in Patients With Mild to Moderate Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Fimasartan 60 mg group|DRUG: Fimasartan 120 mg group|DRUG: Reference (Valsartan 80 mg) group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Web-Based Tailored Nursing Intervention to Increase Walking in Patients After an Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: BEHAVIORAL: TAVIEenM@RCHE|BEHAVIORAL: Publicly available websites
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized Controlled Trial Evaluating an Online Intervention in Increasing Seasonal Influenza Vaccination Among Community Dwelling People Aged ≥65 Years
Status: COMPLETED
Conditions: Vaccination Refusal
Interventions: BEHAVIORAL: online health promotion video|BEHAVIORAL: Control (same online health promotion video)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Motexafin Gadolinium and Docetaxel for Advanced Solid Tumors
Status: COMPLETED
Conditions: Breast Neoplasms|Ovarian Neoplasms|Prostatic Neoplasms|Lung Neoplasms
Interventions: DRUG: Motexafin Gadolinium Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Antibiotic Pretreatment on the Efficacy of WMT in the Treatment of Irritable Bowel Syndrome
Status: NOT_YET_RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Ornidazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesia in Patients Undergoing Percutaneous Nephrolithotomy
Status: RECRUITING
Conditions: Postoperative Analgesia
Interventions: DRUG: Intravenous lidocaine infusion|OTHER: Erector spinae plane block (ESPB)|OTHER: Intravenous infusion of normal saline|OTHER: ESPB with normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: The Branch-based Intraoperative Stent System in the Treatment of Stanford A Aortic Dissection（BROAD）
Status: ENROLLING_BY_INVITATION
Conditions: Aortic Dissection|Aneurysm, Dissecting|Aneurysm|Vascular Diseases|Cardiovascular Diseases
Interventions: DEVICE: PerMed Stent Graft System In Surgical Operation|DEVICE: Endovastec CRONUS® Intraoperative stent system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Live Feedback to Increase Adherence in Adolescents With Patellofemoral Pain
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome|Musculoskeletal Disorders|Joint Diseases
Interventions: OTHER: Feedback on TUT|OTHER: No feedback on TUT|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Linking Education, Produce Provision, and Community Referrals to Improve Diabetes Care (LINK)
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Nutrition Poor|Food Deprivation
Interventions: BEHAVIORAL: Mid-Ohio Food Farmacy|BEHAVIORAL: Mid-Ohio Food Farmacy + Cooking for Diabetes|BEHAVIORAL: Mid-Ohio Food Farmacy + Health Impact Ohio Pathways Hub|BEHAVIORAL: Mid-Ohio Food Farmacy + Cooking for Diabetes + Health Impact Ohio Pathways Hub
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Setmelanotide in Pediatric Participants With Rare Genetic Diseases of Obesity
Status: ACTIVE_NOT_RECRUITING
Conditions: Bardet-Biedl Syndrome|POMC Deficiency Obesity|PCSK1 Deficiency Obesity|LEPR Deficiency Obesity
Interventions: DRUG: Setmelanotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Examination of Inguinal Lymph Node Used to Evaluate the Effect of Acupuncture on Knee Osteoarthritis
Status: ENROLLING_BY_INVITATION
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Acupuncture treatment|DEVICE: False Needle treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impacts of Clean Cookstoves and Empowerment Training on Women's Health in Refugee Settings
Status: COMPLETED
Conditions: Gender-based Violence|Adherence|Mental Health Wellness 1|Empowerment|Food Insecurity|Relationship, Family
Interventions: DEVICE: Inyenyeri clean cookstove and fuel system|BEHAVIORAL: I-ACT (Individual, Agency-Centered Training) workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: TPO-RA in Primary Immune Thrombocytopenia (ITP) in Patients Older Than 14 Years
Status: RECRUITING
Conditions: Primary Immune Thrombocytopenic Purpura
Interventions: DRUG: TPO-RA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Botulinum Toxin Type A in Subjects With Postherpetic Neuralgia
Status: COMPLETED
Conditions: Postherpetic Neuralgia
Interventions: DRUG: Botulinum Toxin Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Tai Chi Chuan as Rehabilitation Program for Mild Cognitive Impairment in Type 2 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Cognitive Dysfunction
Interventions: BEHAVIORAL: Tai Chi Chuan|BEHAVIORAL: Fitness Walking|BEHAVIORAL: Standard Diabetic Care Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Chemotherapy With Bevacizumab for Colorectal Carcinomatosis French Part of the Main Bev-IP Study
Status: WITHDRAWN
Conditions: Colorectal Carcinomatosis
Interventions: PROCEDURE: Cytoreductive surgery combined with HIPEC|DRUG: bevacizumab and HIPEC (Oxaliplatin 360 mg/m2).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Music and Progressive Relaxation Exercise on Fatigue and Sleep in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Fatigue|Sleep
Interventions: OTHER: Progressive relaxation exercise|OTHER: Listening to music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Selected Lysosomal Enzyme Activities and the Oxidant-antioxidant Balance in Hyperbaric Oxygen Condition.
Status: COMPLETED
Conditions: Hyperbaric Oxygenation|Oxygen Toxicity|Antioxidants|Oxidative Stress
Interventions: PROCEDURE: Hyperbaric Oxygen Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Trial of Two Mask Systems in Preventing SARS CoV-2 in Healthcare Workers (HCW)
Status: UNKNOWN
Conditions: SARS CoV-2 Infection|Influenza -Like Illness
Interventions: DEVICE: Acteev™ Masks|DEVICE: Comparison Masks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Laparoscopic Augmented Reality for Identification of Liver Lesions - a Pre-clinical Randomized Cross-over Trial
Status: UNKNOWN
Conditions: Laparoscopy|Augmented Reality|Orientation, Spatial|Liver
Interventions: OTHER: Method A|OTHER: Method B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy Study of Etanercept (Enbrel) on the Response Rate of HIV-infected Subjects
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Etanercept (Enbrel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab in Preventing Lung Cancer in Patients With Stage I-II Non-Small Cell Lung Cancer or High-Risk Pulmonary Nodules, the IMPRINT-Lung Study
Status: RECRUITING
Conditions: Lung Non-Small Cell Carcinoma|Stage I Lung Cancer AJCC v8|Stage IA1 Lung Cancer AJCC v8|Stage IA2 Lung Cancer AJCC v8|Stage IA3 Lung Cancer AJCC v8|Stage IB Lung Cancer AJCC v8|Stage II Lung Cancer AJCC v8|Stage IIA Lung Cancer AJCC v8|Stage IIB Lung Cancer AJCC v8
Interventions: BIOLOGICAL: Pembrolizumab|OTHER: Quality-of-Life Assessment|PROCEDURE: Computed Tomography|PROCEDURE: Biospecimen Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Upfront Systematic Tumour BRCA Testing in Patients With High Grade Serous or Endometrioid Ovarian, Fallopian Tube or Primary Peritoneal Cancer (HGSEC): The t-BRCA Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Serous Ovarian Tumor|Endometrioid Carcinoma Ovary|Fallopian Tube Cancer|Primary Peritoneal Carcinoma
Interventions: GENETIC: Somatic and Germline BRCA1/2 Testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Enhancing Cognitive Training Through Exercise Following a First Schizophrenia Episode
Status: COMPLETED
Conditions: Schizophrenia|Schizophreniform Disorder|Schizoaffective Disorder
Interventions: BEHAVIORAL: Cognitive Training|BEHAVIORAL: Aerobic Exercise|BEHAVIORAL: Case management and supportive psychotherapy|BEHAVIORAL: Individual Placement and Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mapping the Target for the MRgFUS Treatment of Tremor
Status: COMPLETED
Conditions: Tremor, Essential|Parkinson's Disease
Interventions: OTHER: Automatic DRT/VIM target-recognition method using MR-SISET and ML approaches|OTHER: Routine clinical MRI protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Safety, Tolerability, PK and PD of SAD or MAD of APX-115 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy|Safety
Interventions: DRUG: SAD: APX-115|DRUG: SAD: Placebo|DRUG: MAD: APX-115|DRUG: MAD: Placebo|OTHER: Food effect: fasted and fed|OTHER: Metabolic probe with or without APX-115
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Osteogenic Action of a Biphasic Bioceramic With Statin in a Third Molar Extraction Model
Status: RECRUITING
Conditions: Bone Loss|Regenerative Inflammation
Interventions: COMBINATION_PRODUCT: Biphasic bioceramic of tricalcium phosphate and hydroxyapatite with simvastatin|OTHER: Bovine Hydroxyapatite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alleviating Trunk Low Back Pain, With an Active Medical Device Study (ATLAS)
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DEVICE: wearing ATLAS device during evaluation at 4th day|OTHER: wearing ATLAS device during evaluation at 5th day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Feasibility of Cryobiopsy From the Bile Duct - CRYLEO
Status: RECRUITING
Conditions: Neoplasms, Bile Duct
Interventions: DEVICE: 1.1mm flexible Cryoprobe SU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Oral Hyaluronic Acid (A+ HA(tm), TOP Pharm.) in Knee Osteoarthritis: Clinical Trial
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: A+ HA(tm)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Chemoprotective Activity of P218 in PfSPZ Challenge Model
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: P218 (1000 mg) Oral Capsules|DRUG: Placebo Oral Capsules|DRUG: P218 (100 mg) Oral Capsules|BIOLOGICAL: PfSPZ Challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Program of Physical Activity, Nutrition and Supportive to Improve the Quality of Life of Breast Cancer Survivors
Status: RECRUITING
Conditions: Quality of Life|Breast Cancer
Interventions: BEHAVIORAL: ADA|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Self-ligating Brackets Plus Minor Surgery in Treating Crowded Cases of Malocclusion
Status: COMPLETED
Conditions: Malocclusion of Anterior Teeth
Interventions: DEVICE: Self-Ligating Brackets|DEVICE: Traditionally-Ligated Brackets|PROCEDURE: Corticotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of PXT3003 in Charcot-Marie-Tooth Type 1A
Status: UNKNOWN
Conditions: Charcot-Marie-Tooth Type 1A
Interventions: DRUG: PXT3003|DRUG: PXT3003 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Placebo-Controlled Cross Over Trial of Chlorzoxazone Intake
Status: COMPLETED
Conditions: Alcohol Abuse
Interventions: DRUG: Parafon Forte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dawneo Neoblazar® Transcatheter Tricuspid Valve Edge-to Edge Repair System Pivotal Clinical Trial in Patients With Severe Tricuspid Regurgitation
Status: UNKNOWN
Conditions: Tricuspid Regurgitation
Interventions: DEVICE: Neoblazar® Transcatheter Tricuspid Valve Edge-to Edge Repair System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo Controlled Double-blind Dose Ranging Study of the Efficacy and Safety of SSR149744C 50, 100, 200 or 300 mg OD With Amiodarone as Calibrator for the Maintenance of Sinus Rhythm in Patients With Recent Atrial Fibrillation/Flutter
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DRUG: CELIVARONE (SSR149744C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Increasing Physical Activity for Adults With Multiple Sclerosis (MS)
Status: RECRUITING
Conditions: Multiple Sclerosis (MS)|Fatigue|Physical Inactivity
Interventions: OTHER: ExerciseRx intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyaluronan in the Treatment of Residual Pockets in Periodontitis Patients.
Status: COMPLETED
Conditions: Periodontitis
Interventions: OTHER: HY containing gel; GUM® Afta Clear Gel, Sunstar|OTHER: saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Pacemaker Algorithm in Promotion of the Intrinsic Heart Activity.
Status: UNKNOWN
Conditions: Bradycardia; Sick Sinus Syndrome, AV Block
Interventions: DEVICE: Vitatron C50 D Model C50A2 of Vitatron C60 DR model C60A2|PROCEDURE: Required pacemaker setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: NeuroQore rTMS (Monophasic vs. Biphasic) for Major Depressive Disorder: A Randomized Controlled Pilot Trial
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DEVICE: NeuroQore rTMS Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the SUNRISE© Device With Ventilatory Polygraphy for the Diagnosis of Obstructive Sleep Apnea Hypopnea Syndrome: Collection of Preliminary Data
Status: RECRUITING
Conditions: Obstructive Sleep Apnea Hypopnea Syndrome
Interventions: DIAGNOSTIC_TEST: SUNRISE© device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gastric Volume After Water or Jelly Ingestion
Status: COMPLETED
Conditions: Fasting|Surgery|Ultrasound Therapy; Complications|Aspiration Pneumonia Due to Regurgitated Food
Interventions: OTHER: water ingestion|DIETARY_SUPPLEMENT: jelly ingestion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nerve Transfers Plus Electrical Stimulation to Improve Hand Function in Cervical Spinal Cord Injury
Status: NOT_YET_RECRUITING
Conditions: Cervical Spinal Cord Injury|Cervical Spinal Cord Paralysis|Tetraplegia|Tetraplegia/Tetraparesis|Tetraplegic Spinal Paralysis
Interventions: DEVICE: Brief intraoperative electrical stimulation|DEVICE: Temporary Postoperative Peripheral Nerve Stimulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of the Influence of Early Preoperative Consultation on Satisfaction and the Average Length of Stay of Patients Who Underwent Total Hip Arthroplasty
Status: WITHDRAWN
Conditions: Orthopedic Surgery
Interventions: PROCEDURE: medical consultation 8 days before surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Treatment of Central Sleep Apnoea in Patients With Heart Failure With Nasal High Flow Therapy (nHFT)
Status: TERMINATED
Conditions: Central Sleep Apnea|Cheyne-Stokes Respiration
Interventions: DEVICE: Nasal high flow oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Lavage With Alcohol - Chlorhexidine for Chemical Matricectomy
Status: UNKNOWN
Conditions: Ingrown Toenail
Interventions: DRUG: 70% alcohol|DRUG: 70% alcohol - 0.5% clorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Functional Assessment and Immediate Rehabilitation of ED Admitted Elderly With Reduced Functional Performance
Status: COMPLETED
Conditions: Functionally-Impaired Elderly
Interventions: OTHER: Funct. assessment+fast rehabilitation|OTHER: Funct. assessment+usual rehabilitation|OTHER: usual assessment+fast rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Animal-assisted Placebo-induced Analgesia
Status: COMPLETED
Conditions: Pain|Relations, Researcher-Subject
Interventions: OTHER: Placebo (PL)|OTHER: Dog only (DO)|OTHER: Animal-assisted placebo (AAPL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Photobiomodulation, Cryotherapy Combined With Compression, and Massage for Recovery
Status: RECRUITING
Conditions: Laser|Muscle; Fatigue, Heart|Muscle Damage
Interventions: OTHER: Photobiomodulation; Cryotherapy, Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Investigating the Effect of Whole-fruit Coffee Extract on Exercise Performance
Status: COMPLETED
Conditions: Caffine and Endurance Performance
Interventions: DIETARY_SUPPLEMENT: CoffeeBerry Supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preliminary Investigation of a Smart Compression Therapy Prototype
Status: COMPLETED
Conditions: Venous Leg Ulcer|Venous Insufficiency of Leg
Interventions: DEVICE: Compression Therapy System Prototype|DEVICE: Standard Compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Alleviates Postoperative Delirium After Brain Tumor Resections
Status: COMPLETED
Conditions: Dexmedetomidine|Postoperative Delirium
Interventions: DRUG: Dexmedetomidine|DRUG: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Gentle Yoga and Dietary Counseling in Improving Physical Function and Quality of Life in Stage I-II Endometrial Cancer Survivors
Status: COMPLETED
Conditions: Obesity|Endometrial Carcinoma
Interventions: PROCEDURE: Gentle yoga therapy|OTHER: counseling intervention|OTHER: educational intervention|OTHER: quality-of-life assessment|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adaptated Physical Activity During Chemotherapy: Evaluation of the Psychological, Physiological and Biological Impact
Status: TERMINATED
Conditions: Cancer
Interventions: OTHER: questionnaires every 6 weeks (T0, T1, T2, T3 and T4)|OTHER: 6-minute walk test) every 6 weeks (T0, T1, T2, T3 and T4)|OTHER: leptin level with a blood test every 12 weeks (T0, T2 and T4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: "DOES MYOBLOC™ IMPROVE FUNCTIONAL HAND USE IN YOUNG CHILDREN WITH A HYPERTONIC UPPER EXTREMITY?"
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DRUG: Botulinum Toxin type B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-01-70
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Alcon Investigational Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation (TMS) in Binge Eating Disorder (BED)
Status: COMPLETED
Conditions: Binge-Eating Disorder
Interventions: DEVICE: MagVenture MagPro R30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality in Rehabilitation of Executive Functions in Children With Attention Deficit Hyperactivity Disorder.
Status: RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Parental Guidance|BEHAVIORAL: Virtual Reality Game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melatonin Use in Patients With Climacterious Symptoms in the Perimenopause
Status: RECRUITING
Conditions: Perimenopausal Disorder
Interventions: DRUG: Melatonin 3 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sodium Benzoate in the Management of Hyperammonemia in Infants, Children and Adolescent With Chronic Liver Disease.
Status: COMPLETED
Conditions: Chronic Liver Disease
Interventions: DRUG: Sodium Benzoate|OTHER: Powdered table sugar as palcebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Eculizumab in Shiga-toxin Related Hemolytic and Uremic Syndrome Pediatric Patients - ECULISHU
Status: COMPLETED
Conditions: Hemolytic Uremic Syndrome of Childhood
Interventions: DRUG: Eculizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Left Ventricular Function and Remodelling During Permanent Pacing
Status: UNKNOWN
Conditions: Sick Sinus Syndrome|AV-Block
Interventions: DEVICE: AAI vs. DDD vs. BIV pacing in different patients groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Nigella Sativa Oil and Sesame Oil in Preventing Phlebitis
Status: RECRUITING
Conditions: Phlebitis|Peripheral Venous Catheterization
Interventions: OTHER: sesame oil application|OTHER: nigella sativa oil application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cast Immobilization Versus Functional Therapy for Acute, Severe Lateral Ankle Sprains
Status: UNKNOWN
Conditions: Ankle Sprain
Interventions: PROCEDURE: Below knee plaster casting|PROCEDURE: Functional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of Pre-operative Chemo/RT Using Xeloda and External Beam RT Followed by Definite Surgery in Patients With Localized Rectal CA
Status: COMPLETED
Conditions: Rectal Neoplasms
Interventions: DRUG: Chemotherapy, radiation therapy & surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Prognostic Accuracy of ABC ( Age, Blood Urea Nitrogen , Co-morbidities ) and Horibe Pre-endoscopy Scoring Systems in Patients With Upper Gastrointestinal Bleeding in Sohag University Hospital .
Status: RECRUITING
Conditions: Upper GI Bleeding
Interventions: DIAGNOSTIC_TEST: history taking , vital signs and labaratory investigations
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Low-frequency rTMS in Aphasia
Status: UNKNOWN
Conditions: Aphasia
Interventions: DEVICE: rTMS over right frontal target|DEVICE: rTMS over right temporal target
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Antithrombotic Treatments After Aortic Valve Replacement. Rivaroxaban: A New Antithrombotic Treatment for Patients With Mechanical Prosthetic Aortic Heart Valve.
Status: TERMINATED
Conditions: Aortic Valve Disease|Heart Valve Prosthesis Implantation|Anticoagulants
Interventions: DRUG: Rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Direct Comparison of Ga-68-DOTATATE and Ga-68-DOTATOC
Status: NOT_YET_RECRUITING
Conditions: Meningioma
Interventions: DRUG: Ga-68- DOTATATE|DRUG: Ga-68-DOTATOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Language and Music, Speech and the Human Beatbox: Theoretical Issues for Research in General and Applied Linguistics
Status: COMPLETED
Conditions: Language
Interventions: OTHER: Nasofibroscopy|OTHER: Electroglottography|OTHER: Air flow measurement + acoustic signal recording|OTHER: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Polyclonal Antilymphocyte Globulin (ATG) & Intestinal Immune Barrier After Kidney Transplantation
Status: UNKNOWN
Conditions: Disorder Related to Renal Transplantation
Interventions: OTHER: Blood and fecal sample.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Open-label vs Double-blind Treatment in IBS
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Placebo Effect|Placebos|Peppermint Oil
Interventions: DRUG: placebo|DIETARY_SUPPLEMENT: peppermint oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: 25-Hydroxyvitamin D Pharmacokinetic Study
Status: COMPLETED
Conditions: Vitamin D Deficiency|Fat Malabsorption
Interventions: DRUG: Calcifediol|DRUG: Calciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Avoiding Health Disparities When Collecting Patient Contextual Data for Clinical Care and Pragmatic Research
Status: COMPLETED
Conditions: Communication
Interventions: BEHAVIORAL: Facilitated Enrollment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH