pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: G-CSF and AMD3100 to Mobilize Stem Cells in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AMD 3100 (Mozobil plerixafor)|DRUG: Granulocyte colony-stimulating factor (G-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Localized Radiation Therapy or Recombinant Interferon Beta and Avelumab With or Without Cellular Adoptive Immunotherapy in Treating Patients With Metastatic Merkel Cell Carcinoma
Status: TERMINATED
Conditions: Merkel Cell Polyomavirus Infection|Stage IV Merkel Cell Carcinoma AJCC v7
Interventions: DRUG: Avelumab|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: MCPyV TAg-specific Polyclonal Autologous CD8-positive T Cells|RADIATION: Radiation Therapy|BIOLOGICAL: Recombinant Interferon Beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EMG Guided Botulinum Toxin Type A Injections for Refractory High Tone Pelvic Floor Dysfunction
Status: COMPLETED
Conditions: High Tone Pelvic Floor Dysfunction
Interventions: OTHER: EMG Guidance of Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Traditional Cigarettes, Electronic and IQOS Cigarettes on Oxidative Stress.
Status: COMPLETED
Conditions: Oxidative Stress Induction|Endothelial Dysfunction|Platelet Activation
Interventions: BEHAVIORAL: Smoke
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nocipoint Therapy Versus Standard Physical Therapy Using Electrical Stimulation in Treating Pain From TMJ Disorder
Status: UNKNOWN
Conditions: Temporomandibular Joint Disorders
Interventions: PROCEDURE: Nocipoint Therapy|PROCEDURE: Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Pharmacokinetics of ABT-199 in Combination With Bendamustine/Rituximab (BR) in Subjects With Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: ABT-199|DRUG: Rituximab|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 12-week Study to Evaluate the Efficacy and Safety of Umeclidinium Compared With Tiotropium in Subjects With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Umeclidinium|DRUG: Umeclidinium matching placebo|DRUG: Tiotropium|DRUG: Tiotropium matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Progressive Resistance Training in Head and Neck Cancer Patients During Concomitant Chemoradiotherapy
Status: TERMINATED
Conditions: Head and Neck Neoplasms|Weight Loss
Interventions: BEHAVIORAL: Progressive Resistance Training|BEHAVIORAL: physical activity|BEHAVIORAL: Diet diary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ADJUST: A Study on MDT Prognostication
Status: COMPLETED
Conditions: Terminal Illness
Interventions: OTHER: Advice from the PiPS-B14 prognostic tool|OTHER: Advice from another clinician
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study of the Variations of Albumin Level for Patients With Unresecable Stage IIIc or Stage IV Melanoma Treated by Anti BRAF and Anti MEK
Status: COMPLETED
Conditions: Unresecable Stage IIIc or IV Melanoma
Interventions: DRUG: dabrafenib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of the Healthy Workplace Participatory Program With Peer-led Teams in Public Sector Healthcare Facilities
Status: UNKNOWN
Conditions: Work-Related Condition|Burnout, Caregiver|Work-related Injury|Musculoskeletal Pain
Interventions: OTHER: CPH-NEW Healthy Workplace Participatory Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Liraglutide, Empagliflozin and Linagliptin on the Cognitive Function in T2DM Patients With Mild Cognitive Impairment: a Multicenter, Randomized, Parallel Controlled Clinical Trial
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus|Mild Cognitive Impairment
Interventions: DRUG: Liraglutide|DRUG: Empagliflozin|DRUG: Linagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oblimersen and Doxorubicin in Treating Patients With Advanced Hepatocellular Carcinoma (Liver Cancer)
Status: COMPLETED
Conditions: Liver Cancer
Interventions: BIOLOGICAL: oblimersen sodium|DRUG: doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the NoseFrida Compared With Bulb Suction at Relieving Objective Signs of Nasal Obstruction and Reducing Return Visits in Pediatric Patients Presenting to the Emergency Department
Status: WITHDRAWN
Conditions: Upper Respiratory Tract Infections|Nasal Suction|Return Emergency Department Visits
Interventions: DEVICE: Bulb suction|DEVICE: NoseFrida
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin-paclitaxel With Retifanlimab or Placebo in Participants With Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (POD1UM-303/InterAACT 2).
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma of the Anal Canal
Interventions: DRUG: carboplatin|DRUG: paclitaxel|DRUG: retifanlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of Intensity-Modulated Proton Therapy (IMPT) for Small Cell Lung Cancer
Status: RECRUITING
Conditions: Small-cell Lung Cancer
Interventions: RADIATION: Proton-beam Therapy for Small Cell Lung Cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATAQ EASY: Artesunate + Amodiaquine Fixed Dose Combination in the Treatment of Uncomplicated Plasmodium Falciparum Malaria
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Artesunate + Amodiaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Determine How Consumption of Dairy Fat Fractions Rich in Phospholipids and Proteins Influence Inflammation in the Fed State-Phase 1
Status: ACTIVE_NOT_RECRUITING
Conditions: Metabolic Syndrome|Obesity
Interventions: DIETARY_SUPPLEMENT: Dairy fat|DIETARY_SUPPLEMENT: Dairy fat + MFGM|DIETARY_SUPPLEMENT: Palm fat|DIETARY_SUPPLEMENT: Palm fat + MFGM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Aspirin for the Treatment of Nonalcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver|Nonalcoholic Steatohepatitis
Interventions: DRUG: Aspirin 81 mg|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of SGN-CD33A in AML Patients
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Acute Myeloid Leukemia|Acute Promyelocytic Leukemia
Interventions: DRUG: HMA|DRUG: SGN-CD33A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane (TAP) Block After Kidney Transplantation
Status: WITHDRAWN
Conditions: Transplantation, Kidney
Interventions: PROCEDURE: Transversus abdominis plane (TAP) block|PROCEDURE: Sham TAP block with normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atelectasis Frequency in Different Ventilation Modes
Status: RECRUITING
Conditions: Pulmonary Atelectasis|Mechanical Ventilation Complication|General Anesthesia|Lung Ultrasound
Interventions: PROCEDURE: Volume controlled ventilation (VCV) mode|PROCEDURE: Pressure controlled ventilation (PCV) mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Performance Evaluation of Urine DNA Methylation Testing for the Detection of Urothelial Carcinoma in Patients With Hematuria
Status: NOT_YET_RECRUITING
Conditions: Hematuria|Urothelial Carcinoma|Bladder Cancer|Ureter Cancer|Renal Pelvis Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Controlled Trial of Renal Denervation for Resistant Hypertension
Status: UNKNOWN
Conditions: Hypertension
Interventions: DEVICE: Radiofrequency ablation catheter|DRUG: Amlodipine, losartan potassium and hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-center Study on the Efficacy and Safety of AI-assisted Navigation System for Biliopancreatic EUS
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: OTHER: Artificial intelligence assistant system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Comparison of Collagenase With Antibiotic Ointment of Minor Partial Thickness Burns
Status: TERMINATED
Conditions: Burn, Partial Thickness
Interventions: DRUG: Collagenase Santyl|DRUG: Bacitracin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the 2-Way Interaction Between Multiple Doses of Epanova™ and a Single Dose of Rosuvastatin (Crestor®)
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DRUG: rosuvastatin 40 mg tablet|DRUG: Epanova™ QD (2 x 1 g capsules)|DRUG: Multiple doses of 4 g Epanova™ with single of rosuvastatin 40 mg dose|DRUG: Multiple (20) oral doses of 2 g Vascepa® every 12 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of S (+) - Ibuprofen in Osteoarthritis Pain
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: S (+) - Ibuprofen|DRUG: Ibuvix® - ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Aerobic Exercises and Laughter Yoga Compared With Yoga in Anxiety/Depression Levels in Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer Survivors
Interventions: OTHER: Online exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating the Clinical Value of Traditional Chinese Medicine in the Adjuvant Therapy of Triple-negative Breast Cancer
Status: UNKNOWN
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Traditional Chinese Medicine Formulation|DRUG: Placebo Formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ixekizumab (LY2439821) in Chinese Participants With Radiographic Axial Spondyloarthritis
Status: COMPLETED
Conditions: Spondyloarthritis
Interventions: DRUG: Ixekizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bronchial Washing Beforeand After Endobronchial Biopsy and Bronchial Brushing
Status: COMPLETED
Conditions: Lung Cancer
Interventions: PROCEDURE: Bronchial washing before endobronchial biopsy and brushing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Investigate Safety, Tolerability and PK Following Single and Multiple Ascending Doses of AZD7295 in Japanese
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: AZD7295|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Bioavailability of Oral Sodium Oligo-mannurarate (GV-971) in Healthy Chinese Male Subjects
Status: COMPLETED
Conditions: Bioavailability
Interventions: DRUG: GV-971|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Measuring Diaphragm Electrical Activity in Neonates Using a Smaller Inter-electrode Distance
Status: RECRUITING
Conditions: Respiratory Distress Syndrome, Newborn|Infant, Premature
Interventions: DEVICE: NVR 4mm Edi catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Treatment of Cannabis Use Disorder Among Adults With Comorbid Attention-Deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Cannabis Use Disorder|Attention-deficit/Hyperactivity Disorder
Interventions: DRUG: Adderall-XR|DRUG: Matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Desmoplastic Small Round Cell Tumor|Ewing Sarcoma of Bone or Soft Tissue|Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Interventions: DRUG: vincristine|DRUG: doxorubicin|DRUG: cyclophosphamide|DRUG: ifosfamide|DRUG: etoposide|DRUG: temozolomide|DRUG: temsirolimus|DRUG: bevacizumab|DRUG: sorafenib|PROCEDURE: surgery|RADIATION: radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Volasertib in Combination With Azacitidine in Japanese Patients With Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia
Status: COMPLETED
Conditions: Myelodysplastic Syndromes|Leukemia, Myelomonocytic, Chronic
Interventions: DRUG: Azacitidine|DRUG: Volasertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Astegolimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Fibrotic Scars With Rapid Acoustic Pulse (RAP) Device
Status: UNKNOWN
Conditions: Scars, Hypertrophic
Interventions: DEVICE: Treatment of hypertrophic scars (Soliton's Rapid Acoustic Pulse (RAP) Device)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Outcomes With Microprocessor Knee Utilization in a K2 Population
Status: ACTIVE_NOT_RECRUITING
Conditions: Lower Limb Amputation Above Knee (Injury)|Congenital Amputation of Lower Limb|Lower Limb Amputation Knee
Interventions: DEVICE: Kenevo or C-Leg 4|DEVICE: Non microprocessor controlled knee (NMPK)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Eculizumab in Refractory Generalized Myasthenia Gravis (REGAIN Study)
Status: COMPLETED
Conditions: Refractory Generalized Myasthenia Gravis
Interventions: BIOLOGICAL: Eculizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Psychotherapy on Quality of Life and Recurrence of Events in Patients With Recurrent Vasovagal Syncope: A Randomized Pilot Study
Status: COMPLETED
Conditions: Syncope
Interventions: PROCEDURE: Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of GSKBiologicals' Hib-MenCY-TT Vaccine vs Licensed Hib Conjugate or Meningococcal Vaccine
Status: COMPLETED
Conditions: Haemophilus Influenzae Type b|Neisseria Meningitidis
Interventions: BIOLOGICAL: GSK Biologicals' Haemophilus influenza type b and Neisseria meningitidis serogroups C and Y-tetanus toxoid conjugate vaccine 792014 vaccine|BIOLOGICAL: ActHIB|BIOLOGICAL: Pediarix|BIOLOGICAL: Prevnar|BIOLOGICAL: Menomune
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Serum Calcium to Phosphorous (Ca/P) Ratio in the Diagnosis of Ca-P Metabolism Disorders: a Multicentre Study
Status: COMPLETED
Conditions: Phosphorus and Calcium Disorders|Parathyroid Diseases|Hyperparathyroidism|Hypoparathyroidism
Interventions: OTHER: No intervention is provided
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination of Strength and Sensorimotor Training
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: OTHER: Sensorimotor training first, followed by strength exercises|OTHER: Strength exercises and sensorimotor exercises alternated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lithium Versus Divalproex for Treating Pediatric Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Lithium|DRUG: sodium divalproex|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Investigative Study of the Safety and Efficacy of Long-term Administration of Aripiprazole in Combination With Mood Stabilizer for the Treatment of Patients With Bipolar Disorder Experiencing a Manic or Mixed Episode
Status: COMPLETED
Conditions: Bipolar I Disorder
Interventions: DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Nociceptive Processing Evoked by Heat Homeostatically Regulated: A Contact-heat Evoked Potentials Study
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Homeostatic Plasticity|DRUG: Topical alone (Capsaicin 8% Patch)|OTHER: Placebo Patch|OTHER: Homeostatic Plasticity (Sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Er,Cr:YSGG Laser in Partial Pupotomy
Status: COMPLETED
Conditions: Laser|Tooth|Pulpotomy
Interventions: PROCEDURE: Partial pulpotomy with laser+MTA|PROCEDURE: Partial pulpotomy with MTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development The Potentiality of β-1,3/1,6-D-Glucan (Polysaccharide Peptide) From Mycelia Extract of Indonesia's Ganoderma Lucidum as Adjuvant Therapy in Patients With Cardiometabolic Syndrome
Status: UNKNOWN
Conditions: Cardiometabolic Syndrome
Interventions: DRUG: β-1,3/1,6-D-Glucan From Mycelia Extract of Indonesia's Ganoderma Lucidum Group|DRUG: Placebo Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of Intravenous vs Oral Acetaminophen for Treatment of Fever in Healthy Adult Males
Status: COMPLETED
Conditions: Fever
Interventions: DRUG: Intravenous acetaminophen plus oral placebo|DRUG: Oral acetaminophen plus IV placebo|BIOLOGICAL: Reference standard endotoxin (RSE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Efficacy of Pembrolizumab Combined With MWA for Advanced NSCLC
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Pembrolizumab|PROCEDURE: microwave ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab, Cyclophosphamide, and an Allogeneic GM-CSF-secreting Breast Tumor Vaccine for the Treatment of HER-2/Neu-Overexpressing Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: BIOLOGICAL: Allogeneic GM-CSF-secreting breast cancer vaccine|DRUG: Trastuzumab|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-1 - 4
Status: WITHDRAWN
Conditions: Heroin Dependence|Opioid-Related Disorders
Interventions: DRUG: Opioid-Related Disorders
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Lapatinib and WBRT for Patients With Brain Metastases From Lung or Breast Tumors
Status: COMPLETED
Conditions: Brain Metastases|Lung Tumors|Breast Tumors
Interventions: DRUG: Lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States
Status: RECRUITING
Conditions: Cirrhosis|Cirrhosis, Liver|Cirrhosis Early|Cirrhosis Due to Hepatitis B|Cirrhosis Advanced|Cirrhosis Infectious|Cirrhosis Alcoholic|Cirrhosis, Biliary|Cirrhosis Cryptogenic|Cirrhosis Due to Hepatitis C|Cirrhosis Due to Primary Sclerosing Cholangitis
Interventions: DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effectiveness of Two Programs for Pain Management and Cognitive Health in Older Black Adults
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain|Physical Activity|Older Adults|Mild Cognitive Impairment
Interventions: BEHAVIORAL: MBCT+w|BEHAVIORAL: ALED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Masks Used by Pregnant Women on Vital Signs and Non Stress Test During The COVID-19
Status: COMPLETED
Conditions: Covid-19|Pregnant|Fetus|Mask
Interventions: BEHAVIORAL: Single surgical mask group, Double surgical mask group, N95 mask group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study Evaluating the Safety of FXR-450 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: FXR 450|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: To Check Effectiveness of Medistus Antivirus Lozenges for Cough
Status: COMPLETED
Conditions: Throat Infection|Pharyngitis|Sore Throat
Interventions: DEVICE: Medistus Antivirus Lozenges
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Laparoscopic Guided Transversus Abdominis Plane (TAP) Block in Sleeve Gastrectomy Procedure.
Status: COMPLETED
Conditions: Obesity, Morbid|Postoperative Pain|Postoperative Nausea and Vomiting
Interventions: PROCEDURE: Transversus abdominis plane block|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Dose Escalation of Stereotactic Radiosurgical Boost for Locally Advanced Esophageal Cancer
Status: TERMINATED
Conditions: Esophageal Neoplasms|Carcinoma, Squamous Cell|Adenocarcinoma|Esophageal Cancer
Interventions: DRUG: Capecitabine (Xeloda)|DRUG: [18-F] Fluorodeoxyglucose (FDG)|DRUG: 5-Fluorouracil (5-FU)|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of SPSIPB on Postoperative Pain in Patients Undergoing Shoulder Surgery
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: OTHER: Serratus posterior superior intercostal plane block (SPSIPB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Osteoplasty in Conjunction With Surgical Treatment of Mandibular Grade III Furcation Defects (FURC-III-OST)
Status: WITHDRAWN
Conditions: Furcation Defects|Periodontal Diseases
Interventions: PROCEDURE: Open flap debridement with osteoplasty|PROCEDURE: Open flap debridement without osteoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-Ranging, Cross-over Study of the Safety and Efficacy of ABT-089 in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention-Deficit/Hyperactivity Disorder
Interventions: DRUG: ABT-089|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep & Stress in Healthcare Providers After Defined Music Intervention Measure by 7-Tesla fMRI & Actigraphy
Status: COMPLETED
Conditions: Stress, Psychological|Burnout, Professional|Sleep Deprivation|Music Therapy
Interventions: OTHER: Music Therapy, prescribed|OTHER: Music Therapy, self-selected
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Influence of Helicobacter Pylori Eradication on Gastric Pathology: a Long-term, Prospective Cohort Study
Status: NOT_YET_RECRUITING
Conditions: Helicobacter Pylori|the Operative Link on Gastric Intestinal Metaplasia|Operative Link on Gastric Intestinal Assessment
Interventions: DEVICE: biopsy|DRUG: H. pylori eradication
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of the Safety and Efficacy of Anacetrapib (MK-0859) Among Participants With Hypercholesterolemia When Added to Ongoing Statin Therapy (MK-0859-022)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Anacetrapib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mid-to Long-Term Outcomes in Chronic Myeloid Leukemia (CML) Patients With Complete Cytogenetic Response After Imatinib as First Line Therapy
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia
Interventions: OTHER: HRQOL Survey Packet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial of YH14755 in Subjects With Dyslipidemia and Type II Diabetes
Status: COMPLETED
Conditions: Dyslipidemia|Type II Diabetes
Interventions: DRUG: YH14755|DRUG: Metformin|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glycaemic Responses to Carbohydrate-rich Meals (GlyCarb)
Status: ENROLLING_BY_INVITATION
Conditions: Glycaemia
Interventions: OTHER: A meal delivering 75 g of carbohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Limbal Relaxing Incision Versus Toric Intraocular Lens for Corneal Astigmatism During Cataract Surgery.
Status: UNKNOWN
Conditions: Astigmatism|Cataract
Interventions: PROCEDURE: Limbal Relaxing Incisions|DEVICE: Toric Intraocular Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Dynamic Taping in Preventing Muscle Fatigue
Status: COMPLETED
Conditions: Fatigue; Muscle, Heart|Shoulder Pain|Sport Injury
Interventions: DEVICE: Sham tape|DEVICE: Dynamic tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PEG-Interferon Alfa-2b and Thalidomide in Treating Patients With Recurrent or Metastatic Melanoma
Status: COMPLETED
Conditions: Intraocular Melanoma|Melanoma (Skin)
Interventions: BIOLOGICAL: PEG-interferon alfa-2b|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Niraparib in Combination With Trastuzumab in Metastatic HER2+ Breast Cancer
Status: RECRUITING
Conditions: Metastatic Breast Cancer|HER2 Positive Breast Carcinoma
Interventions: DRUG: Niraparib|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Survival Prolongation by Rationale Innovative Genomics
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer Metastatic|Non-small Cell Lung Cancer Stage IIIB
Interventions: DRUG: Avelumab|DRUG: Axitinib|DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pre- and Probiotics on P-cresol Plasma Levels in Patients Bearing a Kidney Allograft
Status: UNKNOWN
Conditions: Renal Insufficiency, Chronic
Interventions: DIETARY_SUPPLEMENT: CONTROL|DIETARY_SUPPLEMENT: SYNBIOTIC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Project Phoenix: Pilot Intervention for Smokers Who Are Not Ready to Quit Smoking
Status: COMPLETED
Conditions: Smoking Cessation|Motivation
Interventions: BEHAVIORAL: Phoenix|BEHAVIORAL: NRT order button|BEHAVIORAL: Factoid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prognostic Value of Myocardial Fibrosis Quantified Using CMR in Patient With Dilated Cardiomyopathy
Status: COMPLETED
Conditions: Cardiomyopathy, Dilated
Interventions: OTHER: CMR using T1 mapping technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunotherapy After Chemotherapy for Patients With Hormone Refractory Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: docetaxel|DRUG: IL2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of Visual Outcomes With Tecnis One-Piece Multifocal Intraocular Lenses Compared With Patients Previously Implanted With Crystalens Aspheric Optic (AO)
Status: COMPLETED
Conditions: To Collect Information About Visual Outcomes and Participant Satisfaction
Interventions: DEVICE: Tecnis one-piece MF IOL|DEVICE: Crystalens AO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calibration and Evaluation of an Audio Pulse Oximeter Sensor (AudioOx) at Ascent and Descent From Simulated Altitude
Status: COMPLETED
Conditions: Blood Oxygen Saturation Level|Heart Rate
Interventions: OTHER: Normobaric hypoxia chamber
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect Of DAAs on miRNA-122 And Insulin Resistance In Chronic HCV Patients
Status: UNKNOWN
Conditions: Chronic Hepatitis c
Interventions: DIAGNOSTIC_TEST: A)microribonucleic acid-122(miRNA-122), B) Hepatitis C virus Real Time Polymerase chain Reaction (HCV RT-PCR)|DIAGNOSTIC_TEST: A)fasting serum glucose, B)Fasting serum insulin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Temperature-Sensitive Liposomal Doxorubicin and Hyperthermia in Treating Women With Locally Recurrent Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim|DRUG: lyso-thermosensitive liposomal doxorubicin(Thermodox)|PROCEDURE: hyperthermia treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Communication Technology in Disseminating HIV Prevention Training to Non-governmental Organizations
Status: COMPLETED
Conditions: HIV Infections
Interventions: BEHAVIORAL: Face-to-face training|BEHAVIORAL: Distance training|BEHAVIORAL: Popular Opinion Leader (POL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Single Dose Escalation and Multiple Dose Escalation Trial of an Intravenous Formulation of MRX-4
Status: COMPLETED
Conditions: Safety
Interventions: DRUG: Single intravenous doses of MRX-4|DRUG: Single intravenous doses of placebo|DRUG: Multiple intravenous doses of MRX-4|DRUG: Multiple intravenous doses of placebo|DRUG: Single dose of intravenous and oral MRX-4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Infrapatellar Strap and Elastic Band Iin Athletes With Patellofemoral Pain Syndrome
Status: UNKNOWN
Conditions: Recruitment
Interventions: DEVICE: Infrapatellar strap|OTHER: Elastic band
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Examination of Transcranial Focused Ultrasound on Brain Activity in Adults
Status: NOT_YET_RECRUITING
Conditions: Impulsive Behavior
Interventions: DEVICE: tFUS|DEVICE: Sham tFUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving Hemodialysis
Status: RECRUITING
Conditions: Secondary Hyperparathyroidism
Interventions: DRUG: Etelcalcetide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Influenza H9 Vaccine in Humans
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: H9N2 whole virus vaccine, IM, 1.5microg|BIOLOGICAL: H9N2 whole virus vaccine, IM, 5microg|BIOLOGICAL: H9N2 whole virus vaccine vaccine, IM, 15microg|BIOLOGICAL: H9N2 whole virus vaccine, IM, 45microg|BIOLOGICAL: H9N2 whole virus vaccine, alum, IM, 1.5microg|BIOLOGICAL: H9N2 whole virus, alum, IM, 5microg|BIOLOGICAL: H9N2 vaccine, whole virus, alum, IM, 15 microg|BIOLOGICAL: H9N2 vaccine, whole virus, alum, IM, 45microg|BIOLOGICAL: H9N2 virosome vaccine, IM, 1.5microg|BIOLOGICAL: H9N2 virosomal vaccine, IM, 5microg|BIOLOGICAL: H9N2 virosomal vaccine, IM, 15microg|BIOLOGICAL: H9N2 virosomal vaccine, IM, 45microg|BIOLOGICAL: H9N2 whole virus vaccine, ID, 5microg|BIOLOGICAL: H9N2 whole virus vaccine, ID, 15microg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect on Envelope of Motion in Asymptomatic Bruxers
Status: RECRUITING
Conditions: Tooth Wear|Bruxism
Interventions: DRUG: Botulinum toxin type A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Telephone Follow-up Procedure on the Quality of Life in Psychogenic Non-epileptic Seizures
Status: UNKNOWN
Conditions: Psychogenic Non Epileptic Seizure
Interventions: OTHER: Telephone follow-up device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Camrelizumab Plus Famitinib as Treatment in Patient With Advanced or Metastatic Pulmonary Sarcomatoid Carcinoma
Status: RECRUITING
Conditions: Sarcomatoid Carcinoma of Lung
Interventions: DRUG: Camrelizumab|DRUG: Famitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epilepsy Adherence in Children and Technology (eACT)
Status: COMPLETED
Conditions: Epilepsy
Interventions: BEHAVIORAL: Education microlearning sessions|BEHAVIORAL: Automated digital reminders|BEHAVIORAL: Problem-solving mHealth module|BEHAVIORAL: Individualized Adherence Feedback Report
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin and Etoposide) for Previously Untreated Aggressive Lung Cancer That Has Spread
Status: COMPLETED
Conditions: Extensive Stage Lung Small Cell Carcinoma|Malignant Solid Neoplasm|Metastatic Malignant Neoplasm in the Brain
Interventions: BIOLOGICAL: Atezolizumab|DRUG: Carboplatin|DRUG: Entinostat|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: M-TAPA vs Intraperitoneal Bupivacain vs Intraperitoneal Bupivacain +Dexmedetomidin
Status: NOT_YET_RECRUITING
Conditions: Regional Anesthesia Morbidity
Interventions: PROCEDURE: application for postoperative analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of JAB-21822 in Adult Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation in China
Status: ACTIVE_NOT_RECRUITING
Conditions: NSCLC|Solid Tumor
Interventions: DRUG: JAB-21822|DRUG: JAB-21822|DRUG: JAB-21822
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing Adherence to Pulmonary Rehabilitation After COPD Related Hospitalizations (Pilot Study)
Status: COMPLETED
Conditions: COPD Exacerbation
Interventions: BEHAVIORAL: Intervention- Home-based Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study to Evaluate the Efficacy and Safety of MGL-3196 (Resmetirom) in Patients With NASH and Fibrosis
Status: ACTIVE_NOT_RECRUITING
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: MGL-3196|DRUG: Placebo|PROCEDURE: Liver Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Different Forms of Creatine
Status: COMPLETED
Conditions: Nutritional Supplements
Interventions: DIETARY_SUPPLEMENT: Creatine nitrate, low dose|DIETARY_SUPPLEMENT: Creatine nitrate, high dose|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: ROSA Total Knee Investigational Testing Authorization Study
Status: TERMINATED
Conditions: Knee Pain|Chronic Osteoarthritis|Avascular Necrosis of Femoral Condyle|Moderate Varus, Valgus or Flexion Deformities|Rheumatoid Arthritis
Interventions: DEVICE: PERSONA Total Knee
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Remediation and Sheltered Employment in Schizophrenia
Status: COMPLETED
Conditions: Chronic Schizophrenia
Interventions: BEHAVIORAL: RECOS (COgnitive REmediation for Schizophrenia)|BEHAVIORAL: TAU (Treatment As Usual)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of GSK3228836 in Participants With Chronic Hepatitis B (CHB)
Status: COMPLETED
Conditions: Hepatitis B
Interventions: DRUG: GSK3228836|DRUG: Placebo|DRUG: Nucleos(t)ide therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Donor Regulatory T Cells in Treating Patients With Visceral Acute Graft-versus-Host Disease After Stem Cell Transplant
Status: WITHDRAWN
Conditions: Graft Versus Host Disease
Interventions: BIOLOGICAL: donor regulatory T lymphocytes|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Bioequivalence Study on Two Gliclazide 80mg Tablet Formulations
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BF-Gliclazide Tablet 80mg|DRUG: Diamicron 80mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of Platelet Rich Fibrin / Biphasic Calcium Phosphate Effect Versus Autogenous Bone Graft on Reconstruction of Alveolar Cleft
Status: UNKNOWN
Conditions: Alveolar Ridge Abnormality
Interventions: OTHER: PRF/ BCP|OTHER: Autogenous bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azithromycin to Improve Latency in Exam Indicated Cerclage Control Trial
Status: RECRUITING
Conditions: Preterm Birth|Obstetric Labor, Premature|Obstetric Labor Complications|Pregnancy Complications|Physiological Effects of Drugs|Uterine Cervical Incompetence|Anti-Bacterial Agents|Azithromycin|Cefazolin
Interventions: DRUG: Azithromycin 1 gram IV|DRUG: Cefazolin and indomethacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dianatal Obstetric Gel (Cross-linked Polyacrylic Acid) on Outcomes in Vaginal Delivery
Status: UNKNOWN
Conditions: Labor, First Stage|Labor, Second Stage
Interventions: DEVICE: Dianatal Obstetric Gel (Cross-linked polyacrylic acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tiradentes Association in the Treatment of Acute Pain
Status: WITHDRAWN
Conditions: Acute Pain
Interventions: DRUG: TIRADENTES ASSOCIATION|DRUG: DIPYRONE|DRUG: TRAMADOL|OTHER: TIRADENTES ASSOCIATION PLACEBO|OTHER: DIPYRONE PLACEBO|OTHER: TRAMADOL PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Moving Mindfully for Freezing of Gait
Status: COMPLETED
Conditions: Parkinson Disease|Mindfulness
Interventions: BEHAVIORAL: Mindfulness Based Walking Therapy (MBWT)|OTHER: Freezing of Gait (FOG) Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Neurobehavioral Measurement of Substance Users in Outpatient Treatment Setting
Status: COMPLETED
Conditions: Cocaine Dependence|Cocaine Use Disorder|Opiate Dependence|Opioid-use Disorder|Cannabis Dependence
Interventions: BEHAVIORAL: Four-Session Mind Freedom Plan|BEHAVIORAL: Treatment as usual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Evaluating Doxercalciferol Replacement Therapy in Kidney Transplant Recipients
Status: COMPLETED
Conditions: Chronic Kidney Disease|Kidney Transplantation
Interventions: DRUG: Doxercalciferol|DRUG: placebo|DRUG: 25-OH Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Education and Counseling for Abstinence From Tobacco After Pregnancy
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases
Interventions: BEHAVIORAL: Motivational Interviewing Telephone Counseling|BEHAVIORAL: Educational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION