pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety, Tolerability, Pharmacokinetics and Efficacy Study of HS-10380 in Patients With Schizophrenia
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: HS-10380|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation of the Bilateral Habenula for Treatment-Refractory Obsessive-Compulsive Disorder
Status: UNKNOWN
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Bilateral surgical implantation of DBS system to habenula
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ekstracorporal Shock Wave Therapy as a Treatment for Erectile Dysfunction in Men After Prostatectomy
Status: SUSPENDED
Conditions: Erectile Function
Interventions: PROCEDURE: Extracorporeal Shockwave Terapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of NOX66 and External Beam Radiotherapy in Patients With Metastatic Castration-resistant Prostate Cancer and Other Solid Tumors
Status: TERMINATED
Conditions: Metastatic Castration-resistant Prostate Cancer and Other Solid Tumors
Interventions: DRUG: NOX66|DRUG: NOX66|DRUG: NOX66|DRUG: NOX66|DRUG: NOX66|RADIATION: EBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET Biomarker Study for Antidepressant Response Prediction in Major Depressive Disorder
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: brain 18F-FDG PET-CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Remote Monitoring of Lung Cancer Patient-Reported Outcomes Using Moovcare®
Status: COMPLETED
Conditions: Lung Cancer|Neoplasms, Lung|Neoplasms, Pulmonary|Pulmonary Cancer|Pulmonary Neoplasms|Cancer of Lung
Interventions: DEVICE: Moovcare® use
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Erector Spinae Plane Block and Intravenous Analgesic in Nefrectomy
Status: COMPLETED
Conditions: Regional Anesthesia Morbidity|Nephrectomy
Interventions: PROCEDURE: erector spinea plane block administered preoperative open nephrectomy|PROCEDURE: intravenous analgesic ( 1 mg/kg tramadol + non-steroid antiinflamatuar paracetamol )drug + 10 mg.kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: ACOU085 for Hearing Loss Prevention in Testicular Cancer Patients Receiving Cisplatin
Status: RECRUITING
Conditions: Cisplatin-induced Hearing Loss
Interventions: DRUG: ACOU085 (bimokalner)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating the Feasibility and Compliance of Manual Lymphatic Drainage Comparing Indocyanine-Green (ICG) Guided vs. Traditional Guided in Patients Undergoing Axillary Node Dissection for the Treatment of Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: ICG-guided manual lymphatic drainage|PROCEDURE: Traditional manual lymphatic drainage|DRUG: Indocyanine green
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Tislelizumab (BGB-A317) Versus Placebo in Combination With Chemoradiotherapy in Participant With ESCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma (ESCC)
Interventions: DRUG: Tislelizumab|DRUG: Placebo|DRUG: Paclitaxel|DRUG: Cisplatin|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Timing of Umbilical Cord Clamping: One to Three Minutes vs. After Cessation of Cord Pulsation
Status: COMPLETED
Conditions: Umbilical Cord
Interventions: OTHER: CESSATION OF CORD PULSE|OTHER: CONTROL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Osteopathic Manipulative Treatment on Reduction of Pain in Complicated Newborns: RCT
Status: UNKNOWN
Conditions: Prematurity
Interventions: OTHER: osteopathic manipulative treatment|OTHER: sham therapy|OTHER: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Corticosteroid Injection in Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: Triamcinolone Acetonide|DRUG: lidocaine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medium Chain Triglycerides and Aerobic Exercise on Ketone Production in Women With or Without Prediabetes
Status: COMPLETED
Conditions: Prediabetic State
Interventions: DIETARY_SUPPLEMENT: MCT|DIETARY_SUPPLEMENT: MCT+ aerobic exercise|DIETARY_SUPPLEMENT: Aerobic exercise|DIETARY_SUPPLEMENT: Control day
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Objective Analysis of Caesarean Scar Pregnancy
Status: COMPLETED
Conditions: Caesarean Scar Pregnancy|Ultrasound Scoring System
Interventions: PROCEDURE: ultrasound-guided/hysteroscopic curettage|PROCEDURE: Procedure/Surgery: laparoscopic removal of the pregnancy lesion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Type 2 DIAbeTes With NAFLD: innOvative Biomarkers of Disease progressioN and clInical outComes
Status: NOT_YET_RECRUITING
Conditions: Metabolic Dysfunction-Associated Liver Disease
Interventions: DIAGNOSTIC_TEST: Non-invasive test for the screening of MASLD-related advanced fibrosis in patients with T2D.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Rate of Leg Curl to Leg Press During Isokinetic Testing
Status: COMPLETED
Conditions: Muscle Strain
Interventions: DEVICE: Isokinetic leg extension/-flexion on a legpress device|DEVICE: Isokinetic leg extension/-flexion on a legcurl device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 1-2 Study of Onapristone in Patients With Advanced Castration-resistant Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer|Metastatic Prostate Cancer|Androgen-independent Prostate Cancer|Recurrent Prostate Cancer
Interventions: DRUG: onapristone|DRUG: abiraterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Histological Comparison of Ridge Preservation Using Mineralized FDBA Alone Versus a Combined Mineralized-Demineralized Freeze Dried Bone Allograft
Status: COMPLETED
Conditions: Tooth Extraction
Interventions: DEVICE: Mineralized freeze-dried bone allograft alone|DEVICE: Combination of Mineralized and demineralized freeze-dried bone allograft alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Non-invasive Ventilation on the Oxygenation of Peripheral Muscle in Hypercapnic COPD Patients
Status: COMPLETED
Conditions: COPD|Hypercapnia
Interventions: DEVICE: non-invasive ventilation (NIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Ascending Dose Study of R4733 in Patients With Advanced Solid Tumors.
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: RG4733|DRUG: RG4733|DRUG: RG4733
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Bioequivalence of a Combined Formulated Tablet
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: Dolutegravir 50 mg/abacavir 600 mg/lamivudine 300 mg|DRUG: Dolutegravir 50 mg|DRUG: abacavir 600 mg/lamivudine 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hydroponic Cultivation in Systemic Nickel Allergy Syndrome
Status: COMPLETED
Conditions: Food Allergy|Food Hypersensitivity|Nickel Sensitivity
Interventions: OTHER: Datterino tomato purée from hydroponic technology|OTHER: Datterino tomato puree from conventional cultivation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Conduction System Pacing Optimized Therapy
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Left ventricular coronary sinus configuration|DEVICE: Conduction system pacing-only configuration|DEVICE: Conduction System Pacing Optimized Therapy (CSPOT) configuration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Yoga vs. Health Education for Chronic Pain in Persons Receiving Opioid Agonist Therapy
Status: COMPLETED
Conditions: Opioid-Related Disorders|Pain, Chronic
Interventions: BEHAVIORAL: hatha yoga|BEHAVIORAL: health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Beta-2 Adrenergic Stimulation and Muscle Glucose Uptake
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Clenbuterol Hydrochloride|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Technology and Family Thriving Study
Status: COMPLETED
Conditions: Alzheimer Disease|Dementia|Caregiver Burnout|Quality of Life|Mental Health Wellness 1|Loneliness|Family Relationship
Interventions: BEHAVIORAL: Virtual Reality|BEHAVIORAL: Video Chat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Empagliflozin on Fibrosis and Cirrhosis in Chronic Hepatitis B
Status: RECRUITING
Conditions: Chronic Hepatitis b|NAFLD|Cirrhosis|Fibrosis, Liver|Empagliflozin|SGLT2 Inhibitors
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Placebo pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative-effectiveness of a Healthy Lifestyle and Asthma Management Program, In-person vs. ONline
Status: NOT_YET_RECRUITING
Conditions: Overweight, Childhood|Obesity, Childhood|Asthma in Children
Interventions: BEHAVIORAL: CHAMPION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Southwest German Interventional Study in Acute Myocardial Infarction III
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: early percutaneous coronary intervention|DEVICE: late percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Acupuncture Therapy on Pain in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Pain, Neck
Interventions: OTHER: Acupuncture|OTHER: Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Cerebral Autoregulation During Surgery
Status: RECRUITING
Conditions: Hip Fractures|Hip Arthropathy|Surgery|Delirium
Interventions: OTHER: Blood pressure management according to cerebral autoregulation|OTHER: Blood pressure management according to usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Open Label Study of Long Term Treatment of Pediatric Treatment of Atopic Dermatitis With Pimecrolimus Cream 1% Within a Usual Clinical Setting
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Pimecrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes of Patients Bilaterally Implanted With the TECNIS® Symfony or TECNIS® Symfony Toric Extended Range of Vision IOL
Status: COMPLETED
Conditions: Cataract
Interventions: PROCEDURE: Cataract surgery with binocular implantation of either Symfony (ZXR00) or Symfony toric (ZXT) IOLs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monocyte Distribution Width (MDW) in the General Population of Emergency Department Patients With and Without Bacteremia
Status: ACTIVE_NOT_RECRUITING
Conditions: Bacteremia|Bacteremia Sepsis|Sepsis|Septic Shock|Severe Sepsis|Emergency Departments|Continuity of Patient Care
Interventions: DIAGNOSTIC_TEST: Monocyte Distribution Width (MDW) , observation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrasound Guided Posterior Quadratus Lumborum Block for Postoperative Analgesia in Gynecologic Surgery
Status: COMPLETED
Conditions: Post-operative Pain|Gynecologic Surgery|Regional Anesthesia
Interventions: DRUG: QL (quadratus lumborum) block administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Orally Administered DS107 in Adult Patients With Moderate to Severe Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DRUG: DS107|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Apatinib Combined With PD-1 in the Treatment of Recurrent or Metastatic Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Apatinib mesylate tablet|DRUG: PD-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Eczema by Specific Probiotic Strains
Status: WITHDRAWN
Conditions: Eczema|Atopic Dermatitis
Interventions: DIETARY_SUPPLEMENT: Ecologic ® Panda II|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Monosialic Gangliosides to Prevent Albumin-bound Paclitaxel Neurotoxicity
Status: COMPLETED
Conditions: Early Breast Cancer
Interventions: DRUG: monosialic gangliosides|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Economic Outcomes With the Use of SERI® Surgical Scaffold in Direct-to-implant Breast Reconstruction
Status: WITHDRAWN
Conditions: Breast Reconstruction
Interventions: DEVICE: Biodegradable (purified) surgical silk scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of a Mammography Decision Aid for Women Aged 75 and Older
Status: COMPLETED
Conditions: Breast Cancer Screening
Interventions: OTHER: Mammography decision aid|OTHER: Home safety pamphlet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Microembolic Detection in Acute Ischemic Stroke Patients With Atrial Fibrillation and Outcome
Status: COMPLETED
Conditions: Infarction, Brain|Embolism|Atrial Fibrillation
Interventions: OTHER: The presence and rate of MES measured by TCD monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability and Pharmacokinetics Study of AIR DNAse Administered by Inhalation to Healthy Adult Volunteers
Status: COMPLETED
Conditions: Cystic Fibrosis (CF)
Interventions: DRUG: AIR DNase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Panobinostat/Bortezomib/Dexamethasone in Relapsed or Relapsed-and-refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Panobinostat Capsules|DRUG: Bortezomib Injection|DRUG: Dexamethasone tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BrotherlyACT: A Culturally Congruent and Technology-Enhanced Youth Violence and Substance Use Intervention for Black Boys and Men
Status: RECRUITING
Conditions: Violence in Adolescence|Substance Use|Avoidance of Healthcare
Interventions: BEHAVIORAL: BrotherlyACT|OTHER: BrotherlyACT Waitlist Control Group (WCG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hypoglycaemia (Low Blood Sugar) in Adults With Diabetes and Adrenal Failure
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Adrenal Insufficiency|Diabetes Mellitus Type 2 - Insulin-Treated
Interventions: DEVICE: Continuous Glucose Monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot Comparative Bioavailability Study of Levodopa Administered Via Levodopa Cyclops™ Relative to INBRIJA®
Status: COMPLETED
Conditions: Parkinson|Parkinson Disease|Parkinson's Disease and Parkinsonism
Interventions: COMBINATION_PRODUCT: Levodopa Cyclops™|COMBINATION_PRODUCT: INBRIJA®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Project Arthritis Recovering Quality of Life Through Education - Hip
Status: UNKNOWN
Conditions: Hip Osteoarthritis
Interventions: BEHAVIORAL: Patients will be submitted to needle lavage, followed by the injection of 3mL of hylan and 1 mL of ropivacaine|BEHAVIORAL: Patients will be submitted to needle lavage, followed by the injection of 0,5mL triamcinolone (10mg) and 1 mL of ropivacaine,
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caregiver as Navigator: Develop Skills Online (CAN-DO)
Status: NOT_YET_RECRUITING
Conditions: Dementia
Interventions: OTHER: Caregiver as Navigator: Develop Skills Online (CAN-DO) program|OTHER: Healthy Living online course
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hold Relax Pectoral Stretch vs Inspiratory Muscle Training
Status: COMPLETED
Conditions: Pulmonary Function in Frail Elderly
Interventions: OTHER: Inspiratory Muscle Training|OTHER: Hold Relax Pectoral Stretch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Canagliflozin in Patients With Acute Decompansted Heart Failure
Status: COMPLETED
Conditions: Chronic Heart Failure|Acute Heart Failure|Diabetes Mellitus
Interventions: DRUG: Canagliflozin|DRUG: Empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Artificial Kidney Initiation in Kidney Injury
Status: COMPLETED
Conditions: Renal Replacement Therapy for Acute Kidney Injury in Intensive Care Unit
Interventions: PROCEDURE: Early RRT strategy|PROCEDURE: Delayed RRT strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of KETO5 XOGenius Beverage on Markers of Physiological and Neurocognitive Health
Status: RECRUITING
Conditions: Cardiovascular Diseases|Hypertension|Cognitive Decline|Diet|Healthy
Interventions: DIETARY_SUPPLEMENT: XO Genius
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study Comparing Veliparib Plus Carboplatin and Paclitaxel Versus Investigator's Choice of Standard Chemotherapy in Adults Receiving First Cytotoxic Chemotherapy for Metastatic or Advanced Non-Squamous Non-Small Cell Lung Cancer (NSCLC) and Who Are Current or Former Smokers
Status: COMPLETED
Conditions: Non-squamous Non-small Cell Lung Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Veliparib|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Percutaneous Needle Aponeurotomy
Status: RECRUITING
Conditions: Dupuytren Disease of Finger
Interventions: PROCEDURE: Percutaneous needle aponeurotomy|PROCEDURE: Open surgery with limited aponeurectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of a New Chemotherapy Agent to Treat Small Cell Lung Cancer
Status: TERMINATED
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: Sagopilone (BAY86-5302, ZK 219477)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PREemptive Analgesia With preGABAlin in HEART Surgery
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: Pregabalin 150mg|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Deep Neuromuscular Block and Moderate Neuromuscular Block on Quality of Recovery in Patients Undergoing Robotic Gastrectomy
Status: COMPLETED
Conditions: General Anesthesia
Interventions: DRUG: Deep neuromuscular blockade|DRUG: Moderate neuromuscular blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exploratory Study of Norepinephrine to Prevent Alopecia in Head and Neck Cancer Patients Treated With Radiotherapy
Status: TERMINATED
Conditions: Alopecia|Radiodermatitis
Interventions: DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dialectical Behavior Therapy vs Enhanced Usual Care for Suicidal and Self-harming Adolescents. 10 Year Follow-up
Status: COMPLETED
Conditions: Self-Harm, Deliberate|Borderline Personality Disorder
Interventions: BEHAVIORAL: Dialectical Behaviour Therapy for Adolescents (DBT-A)|BEHAVIORAL: Enhanced usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of Different Formulations of GlaxoSmithKline (GSK) Biologicals H7N1 Influenza Vaccine Administered to Adults 65 Years of Age and Older
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Investigational H7N1 vaccine GSK2789869A|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Promoting Neuroplastic Changes of Patients With TBI
Status: NOT_YET_RECRUITING
Conditions: Traumatic Brain Injury
Interventions: DEVICE: Motor relearning training with wearable ankle robot|DEVICE: Passive stretching with wearable ankle robot|DEVICE: Gamed-based active movement training with wearable ankle robot|DEVICE: Passive movement with limited wearable ankle robot|DEVICE: Active movement training with limited wearable ankle robot|DEVICE: Ankle torque and motion measurement with limited wearable ankle robot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic Evaluation of Antiplatelet Effect of Swallowing Versus Chewing Ticagrelor in Patients With Acute Coronary Syndrome
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Chewed ticagrelor|DRUG: Swallowed ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ADVANCE CRT - D: Antitachycardia Pacing (ATP) Delivery for Painless Implantable Cardioverter Defibrillator (ICD) Therapy
Status: COMPLETED
Conditions: Tachycardia, Ventricular|Ventricular Fibrillation
Interventions: DEVICE: Implantable Cardiac Defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Empowerment-based Program on Post-discharge Glycemic Control, and Foot Ulcer
Status: WITHDRAWN
Conditions: Diabetic Foot Ulcer
Interventions: BEHAVIORAL: individual empowerment-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Variability in Spinopelvic Parameters Among Patients Undergoing Total Hip Arthroplasty
Status: ENROLLING_BY_INVITATION
Conditions: Osteoarthritis, Hip
Interventions: DIAGNOSTIC_TEST: EOS X-Ray
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study To Determine The Effects Of Doses Of Relacatib On The Metabolism Of Acetaminophen, Ibuprofen And Atorvastatin
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Relacatib|DRUG: Acetaminophen|DRUG: Ibuprofen|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ultrasound and Exercises in Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Group I|OTHER: Group II|OTHER: Group III|OTHER: Group IV|OTHER: Group V
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Grazoprevir (MK-5172) and Elbasvir (MK-8742) Combination in Treatment-Naïve Hepatitis C Virus Participants (MK-5172-067)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Grazoprevir/Elbasvir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of FT011 in Systemic Sclerosis
Status: COMPLETED
Conditions: Scleroderma, Systemic|Scleroderma, Diffuse|Sclerosis, Systemic
Interventions: DRUG: FT011|DRUG: FT011|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peptide-based Immunization for Colon- and and Pancreas-carcinoma
Status: COMPLETED
Conditions: Colon Neoplasm|Colon Adenocarcinoma|Colon Cancer|Colo-rectal Cancer|Rectal Cancer|Rectal Neoplasms|Rectal Adenocarcinoma|Rectal Tumors|Pancreatic Cancer|Pancreas Cancer|Pancreatic Neoplasms|Pancreatic Adenocarcinoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Complementary and Alternative Medicine (CAM) for Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: Group Education and Stretching|PROCEDURE: Group Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxygen Nanobubble Drink Impact on Exercise in Pulmonary Fibrosis
Status: COMPLETED
Conditions: Pulmonary Fibrosis
Interventions: DIETARY_SUPPLEMENT: Oxygen Nanobubble|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Prolonged Apnea Supported by High Frequency Non-invasive Ventilation.
Status: UNKNOWN
Conditions: Non-invasive Ventilation|High-frequency Ventilation|Healthy Volunteer|Lung Diseases
Interventions: DEVICE: High-frequency non-invasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pharmacokinetic Study of Pyrotinib and Docetaxel in Combination With Trastuzumab in Patients With HER2 Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Docetaxel, trastuzumab|DRUG: Pyrotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Mindfulness-based Cognitive Therapy for Parents of Children With Food Allergies
Status: COMPLETED
Conditions: The Quality of Life of Parents of Children With Food Allergy
Interventions: BEHAVIORAL: Mindfulness-based cognitive therapy|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab With or Without Chemotherapy Before Surgery in Treating Patients With Stage I-IIIA Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Lung Non-Small Cell Carcinoma|Stage I Lung Cancer AJCC v8|Stage IA1 Lung Cancer AJCC v8|Stage IA2 Lung Cancer AJCC v8|Stage IA3 Lung Cancer AJCC v8|Stage IB Lung Cancer AJCC v8|Stage II Lung Cancer AJCC v8|Stage IIA Lung Cancer AJCC v8|Stage IIB Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8
Interventions: DRUG: Cisplatin|BIOLOGICAL: Pembrolizumab|DRUG: Pemetrexed|DRUG: Pemetrexed Disodium|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Different Intervals of Pulsed Dye Laser Sessions on Improvement of Surgical Scars
Status: WITHDRAWN
Conditions: Scar
Interventions: PROCEDURE: pulsed dye laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of CBX129801 in Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy
Interventions: DRUG: CBX129801
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: I.D.E.A.L.-I.C.U. (Initiation of Dialysis EArly Versus deLayed in Intensive Care Unit)
Status: TERMINATED
Conditions: Septic Shock|Acute Renal Failure (as Defined by the "Failure" Stage of the RIFLE Classification)
Interventions: PROCEDURE: Renal Remplacement Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pre-analytical Factors Affecting ctDNA Analysis in Early and Locally Advanced Breast Cancer
Status: RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Early Stage Breast Carcinoma|Locally Advanced Breast Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Electronic Health Record Review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study on the Clinical and Mechanism of Wenyang Huoxue Decoction in Treating Heart Failure After Myocardial Infarction
Status: UNKNOWN
Conditions: Heart Failure|Myocardial Infarction
Interventions: DRUG: Wenyang Huoxue Decoction|DRUG: Wenyang Huoxue placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VALOR: Vaginal Atrophy & Long-term Observation of Recovery
Status: RECRUITING
Conditions: Atrophic Vaginitis|Vaginal Atrophy|Genitourinary Syndrome of Menopause|Lichen Sclerosus of Vulva|Lichen Planus of Vulva|Lichen Simplex of Vulva (Disorder)
Interventions: DEVICE: 7-0940
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain Management After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Postoperative Pain|Knee Arthroplasty
Interventions: PROCEDURE: Epidural analgesia - Group E|PROCEDURE: Femoral blockade - Group F|PROCEDURE: Intraarticular infusion - Group I
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients
Status: RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Anorexia|Hematopoietic and Lymphoid Cell Neoplasm
Interventions: DRUG: Olanzapine|DRUG: Megestrol Acetate|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Test the Safety and Efficacy of Sitagliptin Compared to Glimepiride in Patients With Type 2 Diabetes on a Stable Dose of Metformin (0431-803)(COMPLETED)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus, Non Insulin Dependent|Diabetes Mellitus, Non-Insulin-Dependent
Interventions: DRUG: sitagliptin|DRUG: Comparator: glimepiride|DRUG: open-label metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vagus Nerve Stimulation to Augment Recovery From Minimally Conscious or Persistently Vegetative States After Traumatic Brain Injury
Status: WITHDRAWN
Conditions: Minimally Conscious States Due to Traumatic Brain Injury|Persistently Vegetative States Due to Traumatic Brain Injury
Interventions: DEVICE: Vagus nerve stimulation;|DEVICE: No stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Entecavir Consolidation on Post-TDF Treatment Durability
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: 0.5mg Baraclude(entecavir)|DRUG: 0.5mg Baraclude(entecavir)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Dexmedetomidine on Inflammatory Cytokines in Patients With Aneurysmal Subarachnoid Hemorrhage
Status: TERMINATED
Conditions: Subarachnoid Hemorrhage, Aneurysmal
Interventions: DRUG: Dexmedetomidine|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osteoporosis and Fragility Fractures Among SLE Patients. (FRAIL Trial)
Status: ACTIVE_NOT_RECRUITING
Conditions: Lupus Erythematosus, Systemic
Interventions: DIAGNOSTIC_TEST: DXA|DIAGNOSTIC_TEST: serum sample|DIAGNOSTIC_TEST: PROs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Tuohy Needle and Quincke Needle During Caudal Epidural Injection
Status: COMPLETED
Conditions: Caudal Epidural Block
Interventions: DEVICE: Tuohy needle group|DEVICE: Quincke needle group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Atypical Contact Lens Powers on Subjects With Astigmatism
Status: COMPLETED
Conditions: Astigmatism
Interventions: DEVICE: senofilcon A toric|DEVICE: galyfilcon A toric
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Biologic Association Between Metabolic Magnetic Resonance-positron Emission Tomograph (MR-PET) and Tissue Measures of Glycolysis in Brain Tumors of Infiltrating Glioblastoma Cells
Status: RECRUITING
Conditions: Glioblastoma Multiforme|Glycolytic Index|Epidermal Growth Factor Receptor
Interventions: DIAGNOSTIC_TEST: pH Measurement of in vivo tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Evaluation of ADCT to Accelerate Perioperative Rehabilitation of Pneumonectomy
Status: UNKNOWN
Conditions: Acupuncture Therapy|Pneumonectomy|Perioperative Period|Analgesia
Interventions: DEVICE: Acupuncture and Drug Compound Technology|OTHER: Routine perioperative management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Telephone-Delivered Behavioral Treatment to Improve the Quality of Life of Older Adults With HIV
Status: COMPLETED
Conditions: HIV Infections|Depression
Interventions: BEHAVIORAL: Telephone-administered coping improvement therapy|BEHAVIORAL: Telephone-administered supportive-expressive therapy|BEHAVIORAL: Individual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Exercise on Vitamin d in Obese
Status: COMPLETED
Conditions: Obesity|Vitamin D Deficiency
Interventions: OTHER: Endurance exercise|OTHER: Resistance exersises.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Fruquintinib Plus FOLFIRI/FOLFOX as Second-line Treatment in Patients With RAS-mutant Metastatic Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Fruquintinib|DRUG: FOLFIRI|DRUG: mFOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reverse Medical Barrel™ Device for Adjunctive Treatment for Wide-Neck, Intracranial, Bifurcating/Branching Aneurysms
Status: COMPLETED
Conditions: Intracranial Bifurcating Aneurysms
Interventions: DEVICE: BARREL VRD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Extended Release and Immediate Release Febuxostat in Participants With Gout and Moderate Renal Impairment
Status: COMPLETED
Conditions: Gout|Moderate Renal Impairment
Interventions: DRUG: Febuxostat IR|DRUG: Febuxostat XR|DRUG: Febuxostat placebo|DRUG: Colchicine|DRUG: Naproxen|DRUG: Lansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Clinical Trial Comparing the Use of Cetirizine to Replace Diphenhydramine in the Prevention of Reactions Related to Paclitaxel
Status: COMPLETED
Conditions: Breast Cancer|Lung Cancer|Ovarian Cancer|Oesophageal Cancer|Head Cancer Neck|Cervical Cancer|Endometrial Cancer
Interventions: DRUG: Diphenhydramine|DRUG: Cetirizine|DRUG: Lactose pill|DRUG: Sodium chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: ALL Adult Consortium Trial: Adult ALL Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Doxorubicin|DRUG: Cytarabine|DRUG: Methotrexate|DRUG: Vincristine|DRUG: Cyclophosphamide|DRUG: Methylprednisone|DRUG: Hydrocortisone Sodium Succinate|DRUG: Dexamethasone|DRUG: 6-MP|DRUG: PEG-Asparaginase|DRUG: Imatinib|DRUG: Etoposide|PROCEDURE: Radiation Therapy|DRUG: E. coli Asparaginase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intact Vagal Innervation and Glucagon-like Peptide-1 (GLP-1) Effects
Status: UNKNOWN
Conditions: Vagotomy, Truncal
Interventions: DRUG: GLP-1|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Insulin Resistance and Central Nervous System (CNS) Function in Type 2 Diabetes
Status: COMPLETED
Conditions: Insulin Resistance|Type 2 Diabetes Mellitus
Interventions: DRUG: pioglitazone|DRUG: nateglinide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Balance Training With TENS for Spastic Diplegic Cerebral Palsy
Status: NOT_YET_RECRUITING
Conditions: Diplegic Cerebral Palsy
Interventions: OTHER: balance training with TENS|OTHER: Balance training with placebo TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the Effect of Spray on Propofol Injection Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: ethyl chloride spray|DRUG: lidocaine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Continuous Endostar Intravenous Infusion Combined With Pemetrexed and Carboplatin in Advanced Non Small Cell Lung Cancer Patients
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Carboplatin|DRUG: Pemetrexed|DRUG: Endostar|DRUG: Centrum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quit4Health Intervention in Supporting Smoking Cessation and Preventing Smoking Initiation in Young Adults
Status: COMPLETED
Conditions: Cigarette Smoking|Current Smoker
Interventions: OTHER: Educational Intervention|OTHER: Questionnaire Administration|BEHAVIORAL: Smoking Cessation Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Knee Injections for the Clinical Management of Knee OsteoArthritis
Status: WITHDRAWN
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Arthrex Angel System used to prepare injection of Bone Marrow Concentrate (BMC)|OTHER: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spinal Cord Stimulation for Restoration of Arm and Hand Function in People With Subcortical Stroke
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke|Brain Diseases|Central Nervous System Diseases|Nervous System Diseases|Cardiovascular Diseases
Interventions: DEVICE: Epidural electrical stimulation (EES) of the cervical spinal cord
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Auditory Nerve Monitoring Using Intra-cochlear Stimulation in Subjects With Acoustic Neuroma
Status: COMPLETED
Conditions: Hearing Loss, Cochlear|Neurinoma of the Acoustic Nerve
Interventions: DEVICE: Neuristim|DEVICE: Cochlear implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Insomnia in Patients Undergoing Chemotherapy and Radiation Therapy for Head and Neck Cancer
Status: WITHDRAWN
Conditions: Fatigue|Head and Neck Cancer|Psychosocial Effects of Cancer and Its Treatment|Sleep Disorders
Interventions: OTHER: medical chart review|OTHER: questionnaire administration|PROCEDURE: fatigue assessment and management|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treating Self-criticism in Adolescents: a Study With Single-case Experimental Design
Status: COMPLETED
Conditions: Adolescent - Emotional Problem|Adolescent Problem Behavior|Nonsuicidal Self Injury|Depressive Symptoms|Anxiety|Self-Criticism
Interventions: BEHAVIORAL: Treating self-criticism
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy of Botulinum Toxin A Plus Oral Tadalafil 5 mg in Diabetic Men With Erectile Dysfunction
Status: RECRUITING
Conditions: Erectile Dysfunction With Diabetes Mellitus
Interventions: DRUG: Botulinum toxin A|DRUG: Tadalafil 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mifepristone in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: mifepristone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT