pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of Rapid Fluid Challenge Under Pulmonary Artery Catheter Monitoring on Physiological Indexes of Patients With Septic Shock
Status: UNKNOWN
Conditions: Septic Shock
Interventions: OTHER: fluid chanllenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iontophoretic Application of Terbinafine Gel to the Large Toe Nail
Status: COMPLETED
Conditions: Onychomycosis
Interventions: OTHER: Electrokinetic Transungual System (ETS) - Terbinafine Gel|OTHER: ETS-Terbinafine Gel|OTHER: ETS-Terbinafine Gel|OTHER: ETS-Terbinafine Gel|OTHER: ETS-Terbinafine Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of ATYR1923 (Efzofitimod) In Participants With Severe Pneumonia Related to COVID-19
Status: COMPLETED
Conditions: SARS-CoV-2 (COVID-19) Severe Pneumonia
Interventions: DRUG: Efzofitimod 1 mg/kg|DRUG: Efzofitimod 3 mg/kg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Lidocaine 4% Cream (LMX4) vs Placebo for Pain Due to Lumbar Puncture in Infants 0-60 Days of Age."
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Lidocaine Cream 4%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feature Detection Study for Validation of Hamamatsu NanoZoomer S360MD Digital Slide Scanner System
Status: COMPLETED
Conditions: Pathology
Interventions: DEVICE: Hamamatsu NanoZoomer S360MD Digital Slide Scanner System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Assessing Bryostatin in the Treatment of Moderately Severe to Severe Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Bryostatin 1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant And Adjuvant Abiraterone Acetate + Apalutamide Prostate Cancer Undergoing Prostatectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Apalutamide|DRUG: Leuprolide|DRUG: Prednisone|DRUG: Abiraterone Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Brain Nitrogen in Partial Ornithine Transcarbamylase Deficiency (OTCD) Using 1 H MRS, DTI, and fMRI
Status: COMPLETED
Conditions: Ornithine Transcarbamylase Deficiency
Interventions: OTHER: MRI scanning|BEHAVIORAL: Cognitive testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Safety and Pharmacokinetics of Repeated Dose of Micafungin as Antifungal Prophylaxis in Children and Adolescents Who Undergo Hematopoietic Stem Cell Transplant
Status: COMPLETED
Conditions: Fungal Infections
Interventions: DRUG: Micafungin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Compare Pharmacokinetics & Pharmacodynamics of Warfarin & Esmolol in the Absence & Presence of MEDI0382
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: MEDI0382|DRUG: Warfarin|DRUG: Esmolol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Electrical Nerve Stimulation and Exercise for Shoulder Pain
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: OTHER: Percutaneous Electrical Nerve Stimulation|OTHER: Placebo Percutaneous Electrical Nerve Stimulation|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of a Mobile HIV Prevention App to Increase HIV and Sexually Transmitted Infections (STI) Testing and PrEP Initiation Among Rural Men Who Have Sex With Men
Status: RECRUITING
Conditions: HIV Infections|STI|HIV Pre-exposure Prophylaxis
Interventions: BEHAVIORAL: Combine mobile app|BEHAVIORAL: Motivational interview|BEHAVIORAL: HIV/STI testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Aerobic Exercise on the Cerebral Arterial System, Cognitive, and Motor Function in Post-stroke Patients.
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: treadmill exercise|DEVICE: Cycle ergometer exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rotigotine Versus Placebo As Double Blind Study To Evaluate The Efficacy In Early Stage Idiopathic Parkinson's Disease Patients
Status: COMPLETED
Conditions: IDIOPATHIC PARKINSON'S DISEASE
Interventions: DRUG: Rotigotine|DRUG: Placebo Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Researching the Effect of Exercise on Cancer
Status: RECRUITING
Conditions: Breast Cancer|Prostate Cancer|Colorectal Cancer|Stage I Breast Cancer|Stage II Breast Cancer|Stage III Breast Cancer|Stage I Prostate Cancer|Stage II Prostate Cancer|Stage III Prostate Cancer|Stage I Colorectal Cancer|Stage II Colorectal Cancer|Stage III Colorectal Cancer
Interventions: OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, and Pharmacokinetics of EVT801 in Patients With Advanced Solid Tumours
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor, Adult
Interventions: DRUG: EVT801
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Intensive Chemotherapy Followed by RIC for Refractory and Relapse ALL
Status: UNKNOWN
Conditions: Lymphoblastic Leukemia, Acute, Adult
Interventions: DRUG: FACE-Flu/Bu/Cy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Telehealthcare Intervention on Glycemic Control in Children and Adolescents With Type 1 Diabetes
Status: UNKNOWN
Conditions: Type 1 Diabetes Mellitus
Interventions: BEHAVIORAL: Telemedicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Givinostat in Duchenne's Muscular Dystrophy Long-term Safety and Tolerability Study
Status: ENROLLING_BY_INVITATION
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Givinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quadratus Lumborum Block Type III Versus Type II Versus Transversus Abdominis Plane Block in Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section|Quadratus Lumborum Block|Transversus Abdominis Plane Block
Interventions: PROCEDURE: Quadratus lumborum block typen II|PROCEDURE: Quadratus lumborum block III|PROCEDURE: Transversus abdominis plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glycemic Responses and Sensory Characteristics of Whole Yellow Pea Flour Added to Novel Functional Foods
Status: COMPLETED
Conditions: Diabetes
Interventions: DIETARY_SUPPLEMENT: Whole wheat banana bread|DIETARY_SUPPLEMENT: Whole pea flour banana bread|DIETARY_SUPPLEMENT: Whole wheat biscotti|DIETARY_SUPPLEMENT: Whole pea flour biscotti|DIETARY_SUPPLEMENT: Whole wheat pasta|DIETARY_SUPPLEMENT: Whole pea pasta|DIETARY_SUPPLEMENT: White bread|DIETARY_SUPPLEMENT: Boiled yellow peas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture Effect on the Rate of Maturation in Post Term Pregnancies.
Status: COMPLETED
Conditions: Pregnancy Beyond 41 Week's Gestation
Interventions: OTHER: Acupuncture|OTHER: Placebo Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High Versus Low Dose of Magnesium Sulfate as Initial Tocolytic Agent for Preterm Labour in Symptomatic Placenta Previa.
Status: COMPLETED
Conditions: Placenta Previa Bleeding
Interventions: DRUG: Magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Specific Elastance in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients
Status: COMPLETED
Conditions: Acute Lung Injury|ARDS
Interventions: BEHAVIORAL: mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Positron Emission Tomography to Evaluate the Effects of Bevacizumab on Intra-tumoral Pharmacokinetics of 5-fluorouracil in Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Neoplasm Metastasis
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Finite Versus Continuous Nucleos(t)Ide Analogues for Chronic Hepatitis B
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Hepatitis b
Interventions: OTHER: Nuc Discontinuation|DRUG: Entecavir or Tenofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Denosumab in Current Users of Bisphosphonates for Glucocorticoid-induced Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Denosumab|DRUG: bisphosphonates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Trial to Compare Three Doses of Meloxicam and Placebo in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Meloxicam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Bioavailability of Aliskiren and Valsartan Combined as a Single Tablet vs. the Same Medications Given Separately to Healthy Subjects.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Aliskiren|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Intervention for Parents of Children With ASD
Status: NOT_YET_RECRUITING
Conditions: Mindfulness
Interventions: BEHAVIORAL: Ecological assessment and intervention|BEHAVIORAL: Audio-based Mindfulness intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of Hypotension Prediction Index to Reduce Intraoperative Hypotension in Major Thoracic Surgery
Status: COMPLETED
Conditions: Hypotension During Surgery
Interventions: DIAGNOSTIC_TEST: "Acumen IQ" guided hemodynamic optimization|DIAGNOSTIC_TEST: "Flotrac" guided hemodynamic optimization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Edrecolomab in Treating Patients With Stage II Colon Cancer
Status: COMPLETED
Conditions: Mucinous Adenocarcinoma of the Colon|Signet Ring Adenocarcinoma of the Colon|Stage IIA Colon Cancer|Stage IIB Colon Cancer|Stage IIC Colon Cancer
Interventions: BIOLOGICAL: edrecolomab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimetabolic 18F-Fluorodeoxyglucose (FDG) and 18F-Fluorocholine (FCH) Positron Emission Tomography (PET) as an Early Predictive Factor of Overall Survival in Patients With Advanced Hepatocellular Carcinoma Treated With Sorafenib
Status: TERMINATED
Conditions: Carcinoma, Hepatocellular
Interventions: OTHER: FDG Positron Emission Tomography|OTHER: FCH Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Assess the Effects and Safety of ZGN-1061 in Overweight and Obese Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Overweight and Obesity
Interventions: DRUG: ZGN-1061|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biweekly FOLFIRI in Advanced Gastric Cancer (AGC) With Failure of Prior Taxane, Fluoropyrimidine, and Cisplatin
Status: COMPLETED
Conditions: Advanced Gastric Cancer
Interventions: DRUG: oxaliplatin, 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of T.R.U.E. TEST® Fragrance Mix and Thimerosal Allergens:Bioequivalence of PVP Formulations
Status: COMPLETED
Conditions: Dermatitis, Contact
Interventions: BIOLOGICAL: TRUE Test allergens Fragrance Mix and Thimerosol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SBRT Combined With PD-1 Antibody and Chemotherapy in Oligometastatic Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: RADIATION: SBRT|DRUG: Camrelizumab|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Efficacy and Safety of Combination Treatment With Dutasteride and Tamsulosin With Tamsulosin Monotherapy, in Men With Moderate to Severe Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: DRUG: Dutasteride 0.5mg capsules|DRUG: Dutasteride placebo capsules|DRUG: Tamsulosin 0.2mg tablets|DRUG: Disintegrating placebo tamsulosin tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility and Safety Study of Vaccination With Poly-ICLC and Peptide-pulsed Dendritic Cells in Patients With Metastatic, Locally Advanced, Unresectable, or Recurrent Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: vacc. w/ Poly-ICLC & peptide-pulsed dendritic cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of GS-5423 and GS-2872 in Combination With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections
Interventions: DRUG: Teropavimab|DRUG: Zinlirvimab|DRUG: Lenacapavir Tablet|DRUG: Lenacapavir Injection|DRUG: Antiretroviral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing the Effect of Transpapillary Pancreas Duct Stent in Resection of the Pancreatic Tail
Status: COMPLETED
Conditions: Pancreas Cancer|Fistula
Interventions: PROCEDURE: stent|PROCEDURE: Distal pancreatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the CD40 Agonistic Monoclonal Antibody APX005M
Status: COMPLETED
Conditions: Cancer|NSCLC|Melanoma|Urothelial Carcinoma|MSI-H|Head and Neck Cancer
Interventions: DRUG: APX005M
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Clinical Study Patients With Androgenetic Alopecia (AGA)
Status: COMPLETED
Conditions: AGA
Interventions: DRUG: CU-40102 Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Driving Pressure Guided Ventilation Versus Conventional Lung Protective Strategy in Morbid Obese Patients Undergoing Laparoscopic Bariatric Surgery
Status: RECRUITING
Conditions: Driving Pressure
Interventions: PROCEDURE: driving pressure guided ventilation|PROCEDURE: Conventional protective lung strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Medication-based Analgesia in Humans- STUDY 2
Status: COMPLETED
Conditions: Pain|Cannabis|Opioid Use
Interventions: DRUG: Within-subject test of blinded study medications
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: High Oxygen Delivery to Preserve Exercise Capacity in Idiopathic Pulmonary Fibrosis Patients Treated With Nintedanib
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: OTHER: 60% Oxygen|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ursodeoxycolic Acid for the Prevention of Relapsing Complications After Gallstone Acute Pancreatitis
Status: NOT_YET_RECRUITING
Conditions: Acute Pancreatitis Due to Gallstones
Interventions: DRUG: Ursodeoxycholic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial Evaluating a 13-valent Pneumococcal Conjugate Vaccine Given With Diphtheria, Tetanus, and Acellular Pertussis Vaccine (DTaP) in Healthy Japanese Infants
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: BIOLOGICAL: 13-valent pneumococcal conjugate vaccine (13vPnC)|BIOLOGICAL: diphtheria, tetanus, and acellular pertussis vaccine (DTaP)|BIOLOGICAL: 7-valent pneumococcal conjugate vaccine (7vPnC)|BIOLOGICAL: DTaP|BIOLOGICAL: DTaP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Faecal Calprotectin to Predict Enteropathy of the Preterm Neonates
Status: COMPLETED
Conditions: Enteropathy, Necrotizing Enterocolitis
Interventions: OTHER: Collection of stool samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Efficacy, PK, and PD Characteristics of Orally Inhaled SB010 in Male Patients With Mild Asthma (Multiple Dose)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: SB010|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Afatinib vs Erlotinib as 2nd TKI After Failure to 1st TKI and Chemotherapy for Metastatic NSCLC
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Afatinib|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Efficacy and Safety of Palonosetron in Treatment of Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Laparoscopic Gynecologic, Abdominal, Other Surgery|General Anesthesia
Interventions: DRUG: Palonosetron|DRUG: placebo control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Choline Source, Gut Microbiota and Trimethylamine-N-oxide Response
Status: COMPLETED
Conditions: Metabolism
Interventions: OTHER: Water-soluble choline|OTHER: Fat-soluble choline|OTHER: No choline control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose-response Study of Sodium Nitroprusside in Children Requiring Controlled Hypotension in the Operating Room
Status: COMPLETED
Conditions: Hypotension
Interventions: DRUG: Nitroprusside|DRUG: Nitroprusside|DRUG: Nitroprusside|DRUG: Nitroprusside
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VITALYST Early Feasibility Study in High-Risk PCI Patients (VITALYST EFS)
Status: RECRUITING
Conditions: High-risk Percutaneous Coronary Intervention|Heart Disease, Coronary
Interventions: DEVICE: VITALYST System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Phase I-Ib/II Study of MBG453 as Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies
Status: TERMINATED
Conditions: Advanced Malignancies
Interventions: DRUG: MBG453|DRUG: PDR001|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Overfeeding Induced Fat-tissue Stimulation
Status: RECRUITING
Conditions: Lipid-induced Insulin Resistance
Interventions: BEHAVIORAL: High-fat overnutrition|BEHAVIORAL: Normocaloric macronutrient-balanced nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Safety and Performance of Centaflow
Status: UNKNOWN
Conditions: Fetal Growth Restriction
Interventions: DEVICE: Centaflow and Standard Care|DIAGNOSTIC_TEST: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors
Status: COMPLETED
Conditions: Deafness|Kidney Diseases|Kidney Neoplasms|Neoplasms|Retinal Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Intralesional Injection of Platelet Rich Plasma in the Treatment of Patients With Erosive Oral Lichen Planus
Status: COMPLETED
Conditions: Erosive Oral Lichen Planus
Interventions: BIOLOGICAL: Platelet rich plasma|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Favezelimab (MK-4280) as Monotherapy and in Combination With Pembrolizumab (MK-3475) With or Without Chemotherapy or Lenvatinib (MK-7902) AND Favezelimab/Pembrolizumab (MK-4280A) as Monotherapy in Adults With Advanced Solid Tumors (MK-4280-001)
Status: COMPLETED
Conditions: Neoplasms
Interventions: BIOLOGICAL: Favezelimab|BIOLOGICAL: Pembrolizumab|DRUG: Oxaliplatin|DRUG: Irinotecan|DRUG: Leucovorin (Calcium Folinate)|DRUG: Fluorouracil [5-FU]|BIOLOGICAL: Favezelimab/Pembrolizumab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen Therapy (HBO2) for Persistent Post-concussive Symptoms After Mild Traumatic Brain Injury (mTBI)
Status: COMPLETED
Conditions: Post-concussive Symptoms|Traumatic Brain Injury
Interventions: DRUG: hyperbaric oxygen|OTHER: sham hyperbaric air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Knee Osteoarthritis by Intra-articular Injection of Bone Marrow Mesenchymal Stem Cells
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Hyaluronic acid|BIOLOGICAL: 10 million Bone marrow mesenchimal stem cells|BIOLOGICAL: 100 million Bone marrow mesenchimal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bootle Blast: Understanding the Family Experience
Status: RECRUITING
Conditions: Cerebral Palsy|Developmental Coordination Disorder|Developmental Disability|Autism Spectrum Disorder|Spinal Cord Injuries|Stroke|Acquired Brain Injury|Motor Skills Disorders
Interventions: DEVICE: Bootle Blast Play Phase (B)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase II Trial Evaluating Irinotecan and Capecitabine Relapsed/Refractory Upper GI Tumours
Status: COMPLETED
Conditions: Upper Gastrointestinal Tumours
Interventions: DRUG: Irinotecan, Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Two Indirect Pulp Capping Agents for Permanent Teeth
Status: UNKNOWN
Conditions: Deep Caries
Interventions: DRUG: Silver diamine fluoride|DRUG: Mineral trioxide aggregate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of an Organizational Skills Intervention for Middle School Students With ADHD
Status: COMPLETED
Conditions: Attention-Deficit/Hyperactivity Disorder (ADHD)
Interventions: BEHAVIORAL: Homework, Organization, and Planning Skills (HOPS) Intervention|BEHAVIORAL: Homework Support Intervention (HSI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Glycemic Index Diet (With Canola Oil) for Type 2 Diabetics
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: low glycemic index diet with canola oil bread|DIETARY_SUPPLEMENT: High fiber diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Telemedicine in Collaboration Between a Psychogeriatric Unit and Nursing Homes
Status: WITHDRAWN
Conditions: Dementia|Behavioural Disorders
Interventions: BEHAVIORAL: Training in person centered care by supervision using video-conference
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of MK-3475 (Pembrolizumab) on the Breast Tumor Microenvironment in Triple Negative Breast Cancer
Status: RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Merck 3475 Pembrolizumab|RADIATION: Intraoperative radiation therapy (IORT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Isoflavones and Peritoneal Dialysis
Status: COMPLETED
Conditions: Peritoneal Dialysis
Interventions: DIETARY_SUPPLEMENT: soy isoflavone|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Evaluation of Contrast Sensitivity and Disability Glare in Refractive Surgery, a Sub-Study of: Initial Evaluation of Excimer Laser Keratorefractive Surgery in U.S. Army Personnel (WU # 2335-99)
Status: COMPLETED
Conditions: Myopia
Interventions: PROCEDURE: LASIK|PROCEDURE: PRK|BEHAVIORAL: Small target contrast sensitivity and disability glare
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Zevalin Before Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Refractory Non Hodgkin Lymphoma|Relapsed Non Hodgkin Lymphoma
Interventions: BIOLOGICAL: rituximab|BIOLOGICAL: ibritumomab tiuxetan|BIOLOGICAL: anti-thymocyte globulin|RADIATION: total nodal irradiation|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: allogeneic hematopoietic stem cell transplantation|DRUG: cyclosporine|DRUG: mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Maintenance of Effect After Long-term Treatment With Sativex® in Subjects With Symptoms of Spasticity Due to Multiple Sclerosis
Status: COMPLETED
Conditions: Spasticity|Multiple Sclerosis
Interventions: DRUG: Sativex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Atacicept in Subjects With Optic Neuritis
Status: TERMINATED
Conditions: Optic Neuritis
Interventions: DRUG: Atacicept|DRUG: Placebo matched to atacicept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intranasal Versus Intravenous Ketamine for Procedural Sedation in Children
Status: COMPLETED
Conditions: Bone Fractures
Interventions: DRUG: Ketamine and saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Prolonged Use of Dronedarone on Recurrence in Patients With Non-paroxysmal Atrial Fibrillation After Radiofrequency Ablation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: Dronedarone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Measurement of Patient Reported Gastrointestinal (GI) and Health-related Quality of Life (HRQL) Outcomes in Renal Transplant Recipients (MyLife)
Status: COMPLETED
Conditions: Renal Transplantation|Gastrointestinal Problems
Interventions: DRUG: Enteric-Coated Mycophenolate Sodium (EC-MPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy Using Methyl-5-Aminolevulinate Hydrochloride Cream in Determining Pain Threshold in Patients With Skin Cancer
Status: COMPLETED
Conditions: Basal Cell Carcinoma of the Skin|Pain|Recurrent Skin Cancer
Interventions: DRUG: methyl-5-aminolevulinate hydrochloride cream|DRUG: photodynamic therapy|PROCEDURE: laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of the Dermal Filler for Female Intimate Area Hydration and Atrophy of the Vagina.
Status: COMPLETED
Conditions: Vaginal Atrophy|Vulvovaginal Signs and Symptoms|Dyspareunia|Urinary Incontinence
Interventions: DEVICE: MMG-23-04-2019
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manual Therapy Versus Exercise on Knee Osteoarthritis
Status: TERMINATED
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Manual Therapy|BEHAVIORAL: Therapeutic Exercise|BEHAVIORAL: Video Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prehabilitation for Cardiac Surgery in Patients With Reduced Exercise Tolerance
Status: UNKNOWN
Conditions: Sarcopenia|Exercise Intolerance|Heart Failure|Peripheral Artery Disease
Interventions: DEVICE: Neuromuscular electrical stimulation (NMES)|DEVICE: Transcutaneous electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deviating the Esophagus in Atrial Fibrillation Ablation
Status: TERMINATED
Conditions: Esophageal Deviation|Atrial Fibrillation|Ablation
Interventions: DEVICE: esophageal deviation with IDE device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, and Pharmacokinetics of BGB-23339 in Healthy Japanese and Caucasian Subjects
Status: WITHDRAWN
Conditions: Healthy Volunteers
Interventions: DRUG: BGB-23339|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Cognitive Behavioral Therapy and Transcranial Current Stimulation (tDCS) on Chronic Lower Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain|Opioid Use, Unspecified
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Pain|DEVICE: Transcranial Direct Current Stimulation|DEVICE: Sham Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: During-exercise Physiological Effects of Nasal High-flow in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Nasal high-flow|OTHER: Sham nasal high-flow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Rovalpituzumab Tesirine (SC16LD6.5) for Third-Line and Later Treatment of Subjects With Relapsed or Refractory Delta-Like Protein 3-Expressing Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Rovalpituzumab tesirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exogenous Ketones and Glucose Tolerance
Status: COMPLETED
Conditions: Ketones|Dietary Supplements
Interventions: DIETARY_SUPPLEMENT: Ketone monoester|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Intervention on Progesterone Levels Before Euploid Embryo Transfer in Pregnancy Outcomes.
Status: COMPLETED
Conditions: Infertility|Progesterone|Frozen Embryo Transfer|Euploid Embryo Transfer|Pregnancy Outcome|Artificial Cycle|Ongoing Pregnancy
Interventions: DRUG: Low Progesterone|DRUG: Normal Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of Isatuximab in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Plasma Cell Myeloma
Interventions: DRUG: Isatuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Elution and Distal Protection During Percutaneous Coronary Intervention in ST Elevation Myocardial Infarction
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Distal protection and drug eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Theraband, Co-contraction and Isometric Exercises in Frozen Shoulder
Status: COMPLETED
Conditions: Frozen Shoulder
Interventions: OTHER: Theraband exercises|OTHER: Co-contraction exercises|OTHER: Isometric exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Validation of Wearable ECG Monitoring Patch, ATP-C120
Status: UNKNOWN
Conditions: Atrial Fibrillation New Onset
Interventions: DEVICE: wearable continuous ECG monitoring patch, ATP-C120
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Student Wellness Workshop Study
Status: COMPLETED
Conditions: Stress|Stress, Psychological|Stress Reaction|Adjustment|Adjustment, Social|Adjustment, Emotional
Interventions: BEHAVIORAL: YESplus workshop|BEHAVIORAL: WOW! workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Evaluation of Coagulation Factors and Point-of-care Devices During Veno-venous ECMO Therapy
Status: COMPLETED
Conditions: Extracorporeal Membrane Oxygenation Complication|Coagulation Factor Deficiency
Interventions: DIAGNOSTIC_TEST: Detailed coagulation monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hypofractionated Radiotherapy for the Treatment of Cervical or Endometrial Cancer
Status: RECRUITING
Conditions: Cervical Carcinoma|Endometrial Carcinoma
Interventions: RADIATION: Hypofractionated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COPE/Healthy Lifestyles for Teens: A School-Based RCT
Status: UNKNOWN
Conditions: Healthy Lifestyle Behaviors|Depressive/Anxiety Symptoms
Interventions: BEHAVIORAL: COPE/Healthy Lifestyles TEEN Program.|BEHAVIORAL: Healthy Teens Attention Control Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: SGLT2 Inhibition in Hemodialysis
Status: RECRUITING
Conditions: Kidney Failure|Hemodialysis|Diabetes Mellitus, Type 2|Chronic Kidney Disease|Left Ventricular Hypertrophy
Interventions: DRUG: Dapagliflozin 10 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of AK0529 in Chinese Infants Hospitalized With RSV
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: AK0529|DRUG: Matching placebo of AK0529
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety of Pedyphar Ointment in Diabetic Foot Ulcer Treatment
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: Pedyphar Ointment|DRUG: Panthenol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of EPA+DHA (SC401B) for Lowering Triglyceride Levels (≥ 500 mg/dL)
Status: WITHDRAWN
Conditions: Severe Hypertriglyceridemia
Interventions: DRUG: Placebo|DRUG: SC401B 2 capsules|DRUG: SC401B 4 capsules|DRUG: SC401B 6 capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Postoperative Adjuvant Chemotherapy With/Without Rh-endostatin on Non-small Cell Lung Cancer in PhaseⅠB
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Pemetrexed|DRUG: Docetaxel|DRUG: rh-Endostatin|DRUG: Cis-platinum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Risperidone and Olanzapine on Thinking
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorders
Interventions: DRUG: Risperidone|DRUG: Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Shape Regulation Mechanism of Yam Pill on Patients With Sarcopenia Based on Intestine-muscle-brain Axis
Status: NOT_YET_RECRUITING
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Yam pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 6 Months Adjuvant Temozolomide (TMZ) vs No Adjuvant TMZ in Newly Diagnosed MGMT Methylated Glioblastoma (GBM)
Status: WITHDRAWN
Conditions: MGMT-Methylated Glioblastoma
Interventions: OTHER: Delay of TMZ|OTHER: Standard of Care (SOC) Adjuvant TMZ (no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Does Salt Intake Improve Mood
Status: UNKNOWN
Conditions: Mood|Salt Intake
Interventions: DIETARY_SUPPLEMENT: Sodium Chloride|OTHER: Placebo capsule|DIETARY_SUPPLEMENT: Water|BIOLOGICAL: No water consumed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Harry Potter as a Novel Educational Paradigm to Improve Mental Wellness in Children: A Prospective Trial
Status: RECRUITING
Conditions: Suicidal Ideation|Suicidal and Self-injurious Behavior|Suicide Attempt
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy Curriculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combined Occipital and Supraorbital Transcutaneous Nerve Stimulation for Treatment of Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DEVICE: Relievion device- Treatment stimulation|DEVICE: Relievion Device- Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IV Versus IM Administration of Oxytocin for Postpartum Bleeding
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: IV Oxytocin + IM placebo|DRUG: IM Oxytocin + IV placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Isolated Hepatic Perfusion in Combination With Ipilimumab and Nivolumab in Patients With Uveal Melanoma Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Uveal Melanoma|Liver Metastases
Interventions: PROCEDURE: Isolated hepatic perfusion|DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Two-Way Crossover Fasted Bioequivalence Study of Nabumetone 750 mg Tablets in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nabumetone 750 mg tablets, single dose|DRUG: Nabumetone 750 mg tablets, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Piperacillin-Tazobactam Continuous Versus Intermittent Infusion for Pseudomonas Aeruginosa
Status: COMPLETED
Conditions: Pseudomonas Aeruginosa Infection
Interventions: DRUG: Piperacillin-Tazobactam continuous infusion|DRUG: Piperacillin-Tazobactam intermittent infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Combined Topical and Systemic Steroid Administrations on Better Early Postoperative Pain Management in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Total Knee Replacement
Interventions: DRUG: Dexamethasone|DRUG: Triamcinolone|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised Multi-centre Study to Compare the Long-term Performance of the Future Hip to 3 Other Implants in Primary Total Hip Replacement
Status: TERMINATED
Conditions: Osteoarthritis|Post-traumatic Arthritis|Collagen Disorders|Avascular Necrosis|Traumatic Femoral Fractures|Nonunion of Femoral Fractures|Congenital Hip Dysplasia|Slipped Capital Femoral Epiphysis|Perthes Disease
Interventions: DEVICE: European Hip|DEVICE: Zweymüller|DEVICE: CLS Spotorno
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduction in Arrhythmia Burden With Left Atrial Posterior Wall Ablation for Persistent AF
Status: WITHDRAWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Intracardiac Catheter Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Selective Vitamin D Receptor Activation on Clinical Outcomes in Septic Patients
Status: NOT_YET_RECRUITING
Conditions: Sepsis
Interventions: DRUG: Paricalcitol injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT