pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effectiveness of Mirror Therapy in Stroke Patients With Unilateral Neglect - A Randomized Controlled Trial
Status: COMPLETED
Conditions: Hemispatial Neglect
Interventions: OTHER: Mirror therapy|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neural Inhibition as a Mechanism of Nicotine Dependence Among Persons With Schizophrenia
Status: COMPLETED
Conditions: Smoking|Nicotine Dependence|Schizophrenia|Schizophreniform Disorders|Schizoaffective Disorder|Psychosis
Interventions: DRUG: Nicotine patch|OTHER: placebo|BEHAVIORAL: smoking cessation group therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Additional Effect of Subthreshold Micropulse Laser to Intravitreous Injection of Bevacizumab on Diabetic Macular Edema
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Macular Edema
Interventions: COMBINATION_PRODUCT: Intravitreal bevacizumab injection with subthreshold micropulse laser|DRUG: Intravitreal bevacizumab injection alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Toxicity Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer (Phase 1a)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-muscle Invasive Bladder Cancer
Interventions: BIOLOGICAL: TARA-002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fetal Tracheal Occlusion in Severe Diaphragmatic Hernia: a Randomized Trial
Status: UNKNOWN
Conditions: Congenital Diaphragmatic Hernia|Congenital Abnormality
Interventions: PROCEDURE: Fetal tracheal occlusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EPI-7386 in Combination With Enzalutamide Compared With Enzalutamide Alone in Subjects With mCRPC
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Enzalutamide|DRUG: EPI-7386 with Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Anti-CD4 Monoclonal Antibody (mAb)-Fragment for the Imaging of Chronic Inflammation in Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Polyarthritis|Rheumatism|Autoimmune Disease|Inflammation
Interventions: RADIATION: Fab-fragment of Anti-human CD4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Non-Surgical Treatment of Peri-Implantitis With Ultrasonic Carbon Tip
Status: RECRUITING
Conditions: Peri-Implantitis|Alveolar Bone Loss
Interventions: PROCEDURE: Ultrasonic Carbon Tip|PROCEDURE: Titanium Curette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Taste Three New Types Of Crizotinib Formulation In Comparison Of An Oral Solution And To Measure The Amount Of Crizotinib In The Body After These Formulations Are Orally Given, Relative To Capsule Formulation
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Crizotinib prototype microsphere 0.529 mg/mg|DRUG: crizotinib prototype microsphere 0.470 mg/mg|DRUG: crizotinib prototype microsphere 0.420 mg/mg|DRUG: crizotinib oral solution|DRUG: crizotinib prototype microsphere 0.529 mg/mg|DRUG: crizotinib prototype microsphere 0.470 mg/mg|DRUG: crizotinib prototype microsphere 0.420 mg/mg|DRUG: crizotinib capsule|DRUG: crizotinib oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Caffeine Ingestion in Prevention of Postoperative Ileus After Caesarean Section.
Status: COMPLETED
Conditions: Postoperative Ileus|Cesarean Section Complications|Caffeine
Interventions: DIETARY_SUPPLEMENT: Nescafe Gold ® coffee|DIETARY_SUPPLEMENT: Nescafe Gold DECAF® coffee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Total Lymphoid Irradiation Pre-HSCT in Severe Congenital Neutropenia
Status: NOT_YET_RECRUITING
Conditions: Severe Congenital Neutropenia|GATA2 Deficiency
Interventions: OTHER: conditioning with TLI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study Looking at the Use of Glibenclamide and metfoRmin Versus stAndard Care in gEstational diabeteS
Status: COMPLETED
Conditions: Pregnancy|Gestational Diabetes
Interventions: DRUG: Glibenclamide|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-ascending Dose Phase 1 Clinical Trial to Evaluate the Safety and PK of DA-5207 TDS in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DA-5207|DRUG: Donepezil Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dose-Finding Study of WS6788A and LSN03-016011/A Enterotoxigenic E. Coli ETEC Challenge Strains That Express CS17
Status: COMPLETED
Conditions: Travelers' Diarrhea
Interventions: BIOLOGICAL: CFA/I and CS17 challenge strain
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Sensor-equipped Ultrathin Pressure Microcatheter Versus Pressure Wire for FFR Measurement
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Disease|Myocardial Ischemia
Interventions: DEVICE: TruePhysioTM Microcatheter|DEVICE: Pressure Wire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Wuling San on Breast Cancer-related Lymphedema
Status: UNKNOWN
Conditions: Breast Cancer|Lymphedema
Interventions: DRUG: Wuling San|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Abdominal Massage on Excretory Activity and Pulmonary Function Tests in Patients After Surgery
Status: COMPLETED
Conditions: Intraabdominal Pressure
Interventions: OTHER: Abdominal massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Functional Performance and Acceptability Study of Synthetic Nitrile, and Latex Graphene, Compared to Standard Latex Male Condom
Status: COMPLETED
Conditions: Functional Performance
Interventions: DEVICE: Synthetic nitrite Condom|DEVICE: Latex and graphene Condom|DEVICE: Standard latex condom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Trial Comparing the Efficacy and Safety of Lacosamide (LCM) to Carbamazepine Controlled-Release (CBZ-CR); Initial Monotherapy in Epilepsy; Subjects Aged 16 and Older
Status: COMPLETED
Conditions: Epilepsy|Monotherapy
Interventions: DRUG: Lacosamide|DRUG: Carbamazepine-Controlled Release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Intravenous 6β-Naltrexol (AIKO-150) in Opioid-Dependent Subjects
Status: COMPLETED
Conditions: Opiate Addiction
Interventions: DRUG: 6β-Naltrexol escalating doses from 0.05-0.5 mg IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Optimal Programming to Improve Mechanical Indices, Symptoms and Exercise in Cardiac Resynchronization Therapy.
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: A|DEVICE: B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diet Induced Ketosis for Brain Injury - A Feasibility Study
Status: COMPLETED
Conditions: Brain Injuries|Traumatic Brain Injury|Subarachnoid Hemorrhage|Stroke|Anoxic Brain Injury|Neuroinfections
Interventions: OTHER: Ketogenic diet with added MCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized, Controlled, Multi-Center, Study Evaluating AutoloGel Therapy for Complete Closure of Wagner Grade 1-4 Diabetic Foot Ulcers, Venous Leg Ulcers and Stage II-IV Pressure Ulcers
Status: WITHDRAWN
Conditions: Impaired Wound Healing
Interventions: DEVICE: AutoloGel|OTHER: Usual and Customary Care (UCC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab in Combination With Chemotherapy for FGFR2-positive Metastatic Gastric Cancer
Status: RECRUITING
Conditions: Metastatic Gastric Cancer|PD-L1 Gene Amplification|FGFR2 Amplification
Interventions: DRUG: Nivolumab|DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of 2 Types of Cervical Specimens in Patients With a Pathological Screening Smear
Status: UNKNOWN
Conditions: Cervical Cancer|Pathological Screening Smear
Interventions: DEVICE: Cytobrush|DEVICE: Kevorkian curette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single Ascending Dose, First-in-Human Study on Safety, Tolerability and Pharmacokinetics of BAY1161116
Status: TERMINATED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: BAY1161116|DRUG: Placebo|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Treatment of High riSk proLiferative Diabetic retinopathY With Intravitreal Aflibercept injectioN
Status: UNKNOWN
Conditions: Proliferative Diabetic Retinopathy
Interventions: DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Obstructive Sleep Apnea Patients Treated With Mandibular Advancement Device
Status: NOT_YET_RECRUITING
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: MANDIBULAR ADVANCEMENT DEVICE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation Research Study: IQ2, NcIQ and IQ101
Status: COMPLETED
Conditions: Heart Failure|Dyspnea|Hypertension|Pacemaker|Trauma
Interventions: DEVICE: Noninvasive Hemodynamic Patient Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Yoga for Psychological Distress in Gynecologic, Gastrointestinal, or Thoracic Cancer
Status: COMPLETED
Conditions: Gynecologic Cancer|Adjustment|Gastrointestinal Cancer|Thoracic Cancer
Interventions: BEHAVIORAL: Stilling the Waters of Uncertainty: A yoga program for women with gynecologic, gastrointestinal (GI), or thoracic cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Color Dental Alteration Caused by Endodontic Treatment
Status: WITHDRAWN
Conditions: Endodontically Treated Teeth|Tooth Discoloration|Root Canal Infection
Interventions: PROCEDURE: endodontic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Stroll Safe Outdoor Fall Prevention Program
Status: COMPLETED
Conditions: Accidental Fall|Injury Prevention|Healthy Aging
Interventions: BEHAVIORAL: Outdoor Fall prevention brochure|BEHAVIORAL: Stroll Safe outdoor fall prevention program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Radial Forearm Versus the Ulnar Forearm Free Flap
Status: TERMINATED
Conditions: Free Tissue Flaps
Interventions: PROCEDURE: Radial Forearm Free Flap|PROCEDURE: Ulnar Forearm Free Flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy Planning by Multi-parametric PET/MRI Imaging in Patients With Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: DRUG: 68Ga-NODAGA-E[c(RGDyK)]2|DEVICE: PET/MRI scan instead of only MRI|DRUG: 68Ga-NODAGA-E[c(RGDyK)]2|DEVICE: PET/MRI scan instead of only MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Drug Interactions Between Paracetamol and Setrons in Pain Management
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: paracetamol /droperidol|DRUG: paracetamol / ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Robotic, Endoscopic and Traditional Open Surgery in Thyroidectomy
Status: UNKNOWN
Conditions: Endoscopy|Robotics|Thyroidectomy|Papillary Thyroid Carcinoma
Interventions: PROCEDURE: conventional open surgery|PROCEDURE: endoscopic thyroidectomy|DEVICE: robotic thyroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib Before and After Stem Cell Transplant in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Diffuse Large B-Cell Lymphoma Activated B-Cell Type|Refractory Diffuse Large B-Cell Lymphoma Activated B-Cell Type
Interventions: PROCEDURE: Autologous Bone Marrow Transplantation|PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Carmustine|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Etoposide|DRUG: Ibrutinib|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan|OTHER: Pharmacogenomic Study|OTHER: Placebo Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Preconditioning in Head and Neck Cancer Reconstruction - A Randomized Controlled Trial
Status: COMPLETED
Conditions: Head and Neck Neoplasms
Interventions: PROCEDURE: Remote ischemic preconditioning|PROCEDURE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Evaluation of a Steroid-Coated Sinus Stent When Used Following Functional Endoscopic Sinus Surgery in Patients With Chronic Sinusitis
Status: COMPLETED
Conditions: Chronic Sinusitis
Interventions: DEVICE: Sinus Stent with drug coating|DEVICE: Non Coated Sinus Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ERAS-007 in Patients With Advanced Gastrointestinal Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Cancer|Metastatic Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: ERAS-007|DRUG: Encorafenib|DRUG: Cetuximab|DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Mydriatic Microdrops for Retinopathy Of Prematurity Screening
Status: COMPLETED
Conditions: Retinopathy of Prematurity
Interventions: DRUG: Microdrop administration of phenylephrine 1.67% and tropicamide 0.33%|DRUG: Standard drop administration of phenylephrine 1.67% and tropicamide 0.33%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Amlodipine-Benazepril 10mg-20mg Capsules in Healthy Subjects Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Amlodipine-benazepril 10 mg-20 mg capsules|DRUG: Lotrel® 10 mg-20 mg capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: The Kaia Hip and Knee Pain Intervention for Self-management of the Pain in Patients With Osteoarthritis.
Status: COMPLETED
Conditions: Knee Osteoarthritis|Hip Osteoarthritis
Interventions: BEHAVIORAL: Kaia hip and knee pain application|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurexan - a Clinical Trial in Short-Term Insomnia Patients
Status: RECRUITING
Conditions: Insomnia|Stress Reaction
Interventions: DRUG: Neurexan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Carrimycin Tablets in HLH Patients With Carbapenem-resistant Infections
Status: NOT_YET_RECRUITING
Conditions: Carbapenem Resistant Bacterial Infection|Hemophagocytic Lymphohistiocytoses
Interventions: DRUG: Carrimycin tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics-based Mycophenolate Mofetil Dosing for GVHD Prevention
Status: COMPLETED
Conditions: Allogeneic Blood and Marrow Transplantation (BMT)|Graft Versus Host Disease
Interventions: DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Instillation of Gemcitabine in Patients With Superficial Bladder Cancer
Status: TERMINATED
Conditions: Bladder Neoplasms
Interventions: DRUG: Gemcitabine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of ICA-17043 (With or Without Hydroxyurea) in Patients With Sickle Cell Anemia.
Status: COMPLETED
Conditions: Sickle Cell Disease|Sickle Cell Anemia
Interventions: DRUG: Low Dose ICA-17043|DRUG: High dose ICA-17043|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Avonex Treatment in Multiple Sclerosis Patients With Neutralizing Antibodies to Interferon Beta Therapy
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: low immunogenic interferon-beta-1a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eplerenone for the Treatment of Central Serous Chorioretinopathy
Status: COMPLETED
Conditions: Central Serous Chorioretinopathy
Interventions: DRUG: 25mg Eplerenone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The LYMPH Trial - Surgical Versus Conservative Complex Physical Decongestion Therapy for Chronic Breast Cancer-Related Lymphedema
Status: RECRUITING
Conditions: Lymphedema, Breast Cancer
Interventions: PROCEDURE: Surgical Intervention|PROCEDURE: Conservative Complex Physical Decongestion Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study To Identify Predictive Biological Markers In Blood And Cyst Fluid Aspirates From Patients With Pancreatic Cyst Lesions
Status: RECRUITING
Conditions: Pancreatic Cystic Lesions
Interventions: OTHER: Pancreatic Cyst Aspiration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Restless Legs Syndrome With Iron Deficiency or Anaemia in the 3rd Trimester of Pregnancy
Status: COMPLETED
Conditions: Restless Leg Syndrome|Iron Deficiency Anemia
Interventions: DRUG: ferric carboxymaltose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of EMLA Cream Assisted Loco-sedation for Office-based Andrology Procedures
Status: RECRUITING
Conditions: Scrotum Disease|Hydrocele Male|Spermatocele|Scrotal Hematocele|Local Anesthesia
Interventions: DRUG: Eutectic mixture of local anesthetics (EMLA; Astra Pharmaceutical Products Inc., Westborough, MA)|OTHER: Control cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Therapy of the Neck Muscles for Treating the Post-dural Puncture Headache After Cesarean Delivery.
Status: RECRUITING
Conditions: Tecar Therapy Efficacy in the Treatment of PDPH
Interventions: PROCEDURE: Capacitive-Resistive Radiofrequency therapy of the neck muscles
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Radiation Therapy, Paclitaxel, and Cisplatin in Treating Patients With Cancer of the Cervix
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DRUG: cisplatin|DRUG: paclitaxel|RADIATION: brachytherapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strategies to Optimize Antiretroviral Therapy Services for Maternal & Child Health: the MCH-ART Study
Status: COMPLETED
Conditions: HIV
Interventions: OTHER: MCH-focused ART services
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Ceftaroline Fosamil Versus Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections
Status: COMPLETED
Conditions: Complicated Skin and Soft Tissue Infection
Interventions: DRUG: Ceftaroline fosamil|DRUG: Vancomycin|DRUG: Aztreonam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kaolin-based Hemostatic Gauze in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Total Blood Loss|Arthropathy of Knee Joint
Interventions: DRUG: Tranexamic acid injection|DEVICE: apply the QCG|DEVICE: apply surgical gauze
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effect of of Albuterol Sulfate Inhalation Aerosol, eq 90 mcg Base (Sun Pharmaceuticals Industries Limited)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Zero-dose|DRUG: 90 mcg of PROAIR® HFA|DRUG: 180 mcg of 90 mcg of PROAIR® HFA|DRUG: 90 mcg of albuterol sulfate inhalation aerosol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Effects of AIR645 on Allergen-Induced Airway Responses in Subjects With Mild Atopic Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: AIR645|DRUG: Physiologic saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of APG-1252 Plus Osimertinib(AZD9291) in EGFR TKI Resistant NSCLC Patients
Status: RECRUITING
Conditions: EGFR Positive Non-small Cell Lung Cancer
Interventions: DRUG: APG-1252|DRUG: Osimertinib Mesylate Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplementation of Vitamin D3 in Patients With Inflammatory Bowel Diseases and Hypovitaminosis D
Status: COMPLETED
Conditions: Crohn's Disease (CD)|Ulcerative Colitis (UC)
Interventions: DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Long Biliopancreatic Limb Versus Long Alimentary Limb in Superobesity, a Randomized Study
Status: UNKNOWN
Conditions: Severe Obesity
Interventions: PROCEDURE: Distal gastrojejunal bypass|PROCEDURE: RYGB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Vitamin E δ-Tocotrienol Administered to Subjects With Resectable Pancreatic Exocrine Neoplasia
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: DRUG: Vitamin E δ-Tocotrienol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Augmenting Mindfulness Training Through Experience-driven Neurofeedback
Status: COMPLETED
Conditions: Stress
Interventions: BEHAVIORAL: EEG-no RTNF|BEHAVIORAL: EEG-RTNF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sensory Training on Activity Limitation, Functional Use of Hand and Quality of Life After Wrist Surgery
Status: UNKNOWN
Conditions: Proprioception
Interventions: PROCEDURE: Sensory Training|OTHER: classical hand therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PEGPH20, Gemicitabine and Nab-Paclitaxel for Pancreatic Ductal Adenocarcinoma
Status: TERMINATED
Conditions: Adenocarcinoma
Interventions: DRUG: PEGPH20|DRUG: Gemcitabine|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Adalimumab and Infliximab Treatment of Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Infliximab|DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Sonography in Elbow Trauma
Status: RECRUITING
Conditions: Elbow Fracture|Radial Head Fracture|Elbow Sprain|Coronoid Process Fracture|Distal Humerus Fracture
Interventions: DEVICE: POCUS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Optoacoustic Characterization of Postprandial Intestinal Blood Flow
Status: COMPLETED
Conditions: Digestive System Disease|Inflammatory Bowel Diseases
Interventions: DIAGNOSTIC_TEST: Multispectral optoacoustic tomography (MSOT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Compare Pharmacokinetics, Pharmacodynamics and Safety of UI059 and UIC202201 in Healthy Subjects
Status: COMPLETED
Conditions: GERD
Interventions: DRUG: UI059|DRUG: UIC202201
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zanubrutinib and Eltrombopag as Second-line Treatment in Adults With Primary Immune Thrombocytopenia
Status: NOT_YET_RECRUITING
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Zanubrutinib|DRUG: Eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant WX-0593 in Resectable ALK-positive or ROS1-positive Non-small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Non-Small Cell Lung Cancer(NSCLC)
Interventions: DRUG: WX-0593 Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunologic Effect of Low Dose Versus High Dose Vitamin D3 in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Vitamin D Deficiency
Interventions: DRUG: Cholecalciferol|DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 2 Doses of Ferrlecit Versus Oral Iron to Treat Iron-deficiency Anemia in Peritoneal Dialysis Patients.
Status: COMPLETED
Conditions: Iron Deficiency Anemia
Interventions: DRUG: Sodium Ferric Gluconate Complex|DRUG: Sodium Ferric Gluconate Complex|DRUG: Oral Iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of the EEG-neurofeedback on Cognitive Function
Status: ACTIVE_NOT_RECRUITING
Conditions: Cognitive Function|Executive Function
Interventions: BEHAVIORAL: electroencephalography-based neurofeedback (EEG-NFB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Early Diagnosis of Pulmonary Nodule Based on Multi-dimension Messages
Status: RECRUITING
Conditions: Pulmonary Nodule, Solitary|Lung; Node
Interventions: DIAGNOSTIC_TEST: The serum, plasma, urine, faeces, peripheral blood mononuclear cell (PBMC), exhaled breath condensate and the clinical characteristics are collected.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Role of Low-intensity Shock Wave Therapy in Penile Rehabilitation Post Nerve Sparing Radical Cysto-prostatectomy
Status: UNKNOWN
Conditions: Bladder Cancer
Interventions: DEVICE: LI-ESWT group|DRUG: PDE-5 inhibitors group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: T-cell Depleted Hematopoietic Stem Cell Boosts Without Conditioning for Poor Marrow Graft Function Following Allogeneic Hematopoietic Stem Cell Transplantation
Status: TERMINATED
Conditions: Hematopoietic Stem Cell Transplant|Poor Marrow Graft Function
Interventions: PROCEDURE: Donor peripheral blood progenitor cells: stimulation, harvesting, isolation and T-cell depletion|DEVICE: CliniMACS Cell Selection System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Reduction of Fasting Glycaemia With Insulin Glargine Improves First and Second Phase Insulin Secretion in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ZIPS Study - Zip Incision Approximation vs. STAPLE
Status: WITHDRAWN
Conditions: Arthroplasty, Replacement, Knee
Interventions: DEVICE: Zip Surgical Skin Closure|DEVICE: Steel Staples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Faecal Microbiota Transplantation for Liver Cirrhosis
Status: RECRUITING
Conditions: Liver Cirrhosis
Interventions: BIOLOGICAL: Faecal microbiota transplantation|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EGFR-TKI With Chemotherapy in NSCLC Patients With Both EGFR Mutation and BIM Deletion Polymorphism
Status: UNKNOWN
Conditions: Non-Small-Cell Lung Cancer
Interventions: DRUG: EGFR-TKI|DRUG: Chemotherapy（pemetrexed/gemcitabine）|DRUG: Chemotherapy（carboplatin）
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chinese Medicine Treatment of Adolescent Sleep Disorders and Sleeping Pills Withdrawal
Status: RECRUITING
Conditions: Traditional Chinese Medicine|Sleep Disorder
Interventions: DRUG: Suanzaoren Decoction and Huanglian Wendan Decoction|DRUG: Zolpidem
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Lenalidomide in Patients With Relapsed or Recurrent Adult T-cell Leukemia-lymphoma
Status: COMPLETED
Conditions: Adult T-Cell Leukemia-Lymphoma
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antegrade Versus Retrograde IV for Blood Draws
Status: COMPLETED
Conditions: There is no Focus on Any Specific Condition
Interventions: PROCEDURE: Peripheral intravenous catheter placement|OTHER: Blood draw|DEVICE: Peripheral intravenous catheter|DRUG: To keep open (TKO) infusion of 0.9% normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chemopreventive Action of Mesalazine on Colorectal Cancer: a Pilot Study for an "in Vivo" Evaluation of the Molecular Effects on β-catenin Signaling Pathway.
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Mesalazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real-world Study for Patients With Advanced Hepatobiliary Tumors
Status: RECRUITING
Conditions: Objective Response Rate|Progression-free Survival|Overall Survival|Disease Control Rate|Duration of Response|Five-year Survival Rate|Quality of Life
Interventions: DRUG: Precision oncology including targeted therapy and immunotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety Study of Polidocanol Injectable Foam for the Treatment of Saphenofemoral Junction (SFJ) Incompetence
Status: COMPLETED
Conditions: Varicose Veins
Interventions: DRUG: Polidocanol injectable foam (PEM)|DRUG: Placebo Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Oral Glucose in Neonates
Status: UNKNOWN
Conditions: Pain
Interventions: OTHER: 30% glucose|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Frequent Interruptions of Prolonged Sitting on Self-perceived Levels of Energy, Mood, Food Cravings and Cognitive Function
Status: COMPLETED
Conditions: Mood|Energy|Food Cravings|Cognitive Function
Interventions: BEHAVIORAL: physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Increasing Lung Transplant Availability Using Normothermic Ex Vivo Lung Perfusion (EVLP) at a Dedicated EVLP Facility
Status: COMPLETED
Conditions: Lung Diseases
Interventions: DEVICE: Centralized Lung Evaluation System|PROCEDURE: Lung Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biofeedback Training and Physical Therapy Program Improves Visual-motor Integration in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Hemiplegic Cerebral Palsy
Interventions: OTHER: physical therapy program|DEVICE: E-Link Upper Limb Exerciser|COMBINATION_PRODUCT: physical therapy program and E-Link Upper Limb Exerciser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Direct Factor Xa Inhibitor Rivaroxaban in Patients With Acute Symptomatic Pulmonary Embolism - The EINSTEIN PE Study
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Enoxaparin overlapping with and followed by VKA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Back2School - CBT Intervention for School Absenteeism
Status: COMPLETED
Conditions: Anxiety Symptoms|Depressive Symptoms|Behavioral Problem|School Absenteeism
Interventions: BEHAVIORAL: Back2School|OTHER: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DNA and RNA Viruses of the Blood Virome of Allogeneic Hematopoietic Stem Cell Transplant Recipients
Status: COMPLETED
Conditions: Hematopietic Stem Cell Transplantation|Blood Virome|RNA Virus Infections|DNA Virus Infections
Interventions: DIAGNOSTIC_TEST: Real time PCR and RT-PCR for DNA and RNA viral species
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Plantar Fasciitis Treatment: Influence of the Possible Presence of Subchondral Bone Edema
Status: RECRUITING
Conditions: Fasciitis, Plantar
Interventions: DEVICE: THEAL (Mectronic, Bergamo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate of Single and Multiple Oral Doses of GM-1020 in Patients With MDD
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: GM-1020
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MRI Biomarkers of Effective Tissue Reperfusion After Thrombectomy of an Acute Proximal Occlusion of the Anterior Circulation
Status: RECRUITING
Conditions: Ischemic Stroke, Acute
Interventions: DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Long Term Safety Trial of z102 and Prednisone in Patients With Moderate to Severe Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Prednisolone-Dipyridamole|DRUG: Prednisone|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Wet Age-Related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: Ranibizumab|BIOLOGICAL: Aflibercept Injection (EYLEA, VEGF Trap-Eye, BAY86-5321)|BIOLOGICAL: Aflibercept Injection (EYLEA, VEGF Trap-Eye, BAY86-5321)|BIOLOGICAL: Aflibercept Injection (EYLEA, VEGF Trap-Eye, BAY86-5321)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Vitamin D for the Prevention of Acute Respiratory Infections in Children
Status: COMPLETED
Conditions: Acute Respiratory Tract Infections
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TLR8 Agonist VTX-2337 and Cetuximab in Treating Patients With Locally Advanced, Recurrent, or Metastatic Squamous Cell Cancer of Head and Neck
Status: COMPLETED
Conditions: Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma|Recurrent Metastatic Squamous Neck Cancer With Occult Primary|Recurrent Salivary Gland Cancer|Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Nasopharynx|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Recurrent Verrucous Carcinoma of the Larynx|Recurrent Verrucous Carcinoma of the Oral Cavity|Salivary Gland Squamous Cell Carcinoma|Stage III Salivary Gland Cancer|Stage III Squamous Cell Carcinoma of the Hypopharynx|Stage III Squamous Cell Carcinoma of the Larynx|Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage III Squamous Cell Carcinoma of the Nasopharynx|Stage III Squamous Cell Carcinoma of the Oropharynx|Stage III Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage III Verrucous Carcinoma of the Larynx|Stage III Verrucous Carcinoma of the Oral Cavity|Stage IV Salivary Gland Cancer|Stage IVA Squamous Cell Carcinoma of the Larynx|Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVA Squamous Cell Carcinoma of the Oropharynx|Stage IVA Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVA Verrucous Carcinoma of the Larynx|Stage IVA Verrucous Carcinoma of the Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Larynx|Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Oropharynx|Stage IVB Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVB Verrucous Carcinoma of the Larynx|Stage IVB Verrucous Carcinoma of the Oral Cavity|Stage IVC Squamous Cell Carcinoma of the Larynx|Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVC Squamous Cell Carcinoma of the Oropharynx|Stage IVC Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVC Verrucous Carcinoma of the Larynx|Stage IVC Verrucous Carcinoma of the Oral Cavity|Tongue Cancer
Interventions: DRUG: TLR8 agonist VTX-2337|BIOLOGICAL: cetuximab|OTHER: laboratory biomarker analysis|OTHER: pharmacogenomic studies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Prophylaxis and Nausea and Vomiting in Cesarean Section Under Regional Anesthesia.
Status: UNKNOWN
Conditions: Intraoperative Nausea-retching-vomiting Episodes|Nausea Scores Will be Evaluated on the Verbal Analog Scale (VAS)
Interventions: DRUG: Antibiotic prophylaxis timing (before skin incision and after cord clamping) for caesarean section
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 480 Biomedical Bioresorbable Scaffold System in the Treatment of de Novo Superficial Femoral Artery (SFA) Lesions
Status: COMPLETED
Conditions: Superficial Femoral Artery Lesions|Atherosclerosis of Femoral Artery
Interventions: DEVICE: 480 Biomedical Bioresorbable Scaffold System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Volume-based Enteral Feeding Improve Nutrient Delivery in Hospitalized Critically Ill Children?
Status: RECRUITING
Conditions: Enteral Feeding
Interventions: PROCEDURE: Volume-based EN|PROCEDURE: Rate-based EN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Levosimendan or Placebo on Exercise in Advanced Chronic Heart Failure
Status: UNKNOWN
Conditions: Heart Failure
Interventions: DRUG: Levosimendan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: Rocatinlimab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Texture and Colour Enhancement Imaging in Improving Detection and Miss Rate of Premalignant Lesions
Status: NOT_YET_RECRUITING
Conditions: Adenoma|Sessile Serrated Adenoma
Interventions: PROCEDURE: TXI (Group A)|PROCEDURE: TXI followed by WLI (Group B)|PROCEDURE: WLI (Group C)|PROCEDURE: WLI followed by TXI (Group D)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: TURKAPNE - The Turkish Sleep Apnea Database: A National, Multicenter, Observational, Prospective Cohort Study
Status: RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Positive Airway Pressure (PAP)|DEVICE: Intraoral device (IOD)|PROCEDURE: Uvuloplasty|OTHER: Conservative treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High-definition Transcranial Direct Current Stimulation for Facilitating Hand Function Recovery After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: HD-tDCS group|DEVICE: Conventional tDCS group|DEVICE: Sham HD-tDCS group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT