pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Central and Peripheral 24-h Blood Pressure Before and After 3 Month of CPAP Treatment in Obstructive Sleep Apnea
Status: UNKNOWN
Conditions: Chronic Kidney Disease|Obstructive Sleep Apnea
Interventions: DEVICE: CPAP - continuous airway pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Perioperative Sivelstat Administration for Liver Resection
Status: COMPLETED
Conditions: Liver Diseases
Interventions: DRUG: sivelstat|DRUG: glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Facilitated-tucking and ShotBlocker on Pain Caused by Vaccination in Healthy Infants
Status: RECRUITING
Conditions: Procedural Pain|Pain, Acute|Nursing Caries
Interventions: OTHER: Facilitated tucking position|DEVICE: ShotBlocker|COMBINATION_PRODUCT: Combined facilitated tucking and ShotBlocker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open-Label, FIH Study Evaluating the Safety, Tolerability, and Efficacy of VCTX211 Combination Product in Subjects With T1D
Status: RECRUITING
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 1|Glucose Metabolism Disorders|Metabolic Disease|Endocrine System Diseases|Autoimmune Diseases|Immune System Diseases
Interventions: COMBINATION_PRODUCT: VCTX211
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: KickStart30: A 30-Day Intervention for Patients With Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Chronic Pain|Stress|Psychological|Healthy|Rheumatoid Arthritis
Interventions: BEHAVIORAL: Wellness Element 1 - Exercise|BEHAVIORAL: Wellness Element 2 - Mindfulness|BEHAVIORAL: Wellness Element 3 - Sleep Hygiene|BEHAVIORAL: Wellness Element 4 - Social Connectedness|BEHAVIORAL: Wellness Element 5 - Nutrition|BEHAVIORAL: Wellness Element 6 - Wellness Exercises|BEHAVIORAL: Wellness Element 7 - Motivational Messages
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Unattended Home Polysomnography and Comparison to In-laboratory Polysomnography in Pediatric Patients
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: Portable sleep monitor|OTHER: In-laboratory Polysomnography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase I Trial Of IMRT Using A Contralateral Esophagus Sparing Technique (CEST) In Locally Advanced Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Carcinoma|Small Cell Lung Carcinoma
Interventions: RADIATION: Contralateral Esophageal Sparing Technique (CEST)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Tramadol Orally Versus an Optimized Dose of Intravenous Tramadol for Postoperative Pain Relief in Ambulatory Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Tramadol per os (Tradonal Odis® orodispersible tablets)|DRUG: Tramadol IV (Tradonal® IV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-nasal Naloxone for Treatment of Impaired Awareness of Hypoglycemia
Status: TERMINATED
Conditions: Hypoglycemia Unawareness|Type 1 Diabetes
Interventions: DRUG: intra-nasal naloxone|DRUG: Intra-nasal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Fasting and Calorie-Restricted Diets on Dopamine and Serotonin Levels Among Obese Women With BED and FA
Status: UNKNOWN
Conditions: Eating Disorders|Intermittent Fasting|Obesity
Interventions: BEHAVIORAL: caloric reduced -intermitted fasting diet|BEHAVIORAL: Daily calorie restriction|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Safety and Performance of a Lumbar Belt
Status: RECRUITING
Conditions: Low Back Pain
Interventions: DEVICE: LumbarBelt SOFT 300|OTHER: Control group LumbarBelt SOFT 300|DEVICE: LumbarBelt MID 500|OTHER: Control group LumbarBelt MID 500
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quality Of Recovery After Pericapsular Nerve Group (PENG) Block For Hip Hemiarthroplasty Under Spinal Anesthesia
Status: RECRUITING
Conditions: Hip Hemiarthroplasty
Interventions: PROCEDURE: Pericapsular Nerve Group (PENG) Block|PROCEDURE: elective hip hemiarthroplasty without receiving a PENG block.|DRUG: bupivacaine 0.5% injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of AG-120 (Ivosidenib) vs. Placebo in Combination With Azacitidine in Participants With Previously Untreated Acute Myeloid Leukemia With an IDH1 Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: Newly Diagnosed Acute Myeloid Leukemia (AML)|Untreated AML|AML Arising From Myelodysplastic Syndrome (MDS)|Leukemia, Myeloid, Acute
Interventions: DRUG: AG-120|DRUG: Placebo|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-escalating Trial With UniCAR02-T Cells and PSMA Target Module (TMpPSMA) in Patients With Progressive Disease After Standard Systemic Therapy in Cancers With Positive PSMA Marker
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Cyclophosphamide (Non-IMP)|DRUG: Fludarabine (Non-IMP)|DRUG: UniCAR02-T-pPSMA|DRUG: UniCAR02-T (IMP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Anesthetic Infusion and Sternotomy
Status: TERMINATED
Conditions: Hyperalgesia|Pain
Interventions: DRUG: Local anesthetic (Ropivacaine)|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Aspirin + Ketamine as Adjunct to Oral Antidepressant Therapy for Depression
Status: COMPLETED
Conditions: Treatment Resistant Depression|Major Depressive Disorder|Analgesia|Ketamine|Peripheral Nervous System Agents|Central Nervous System Depressants|Neurotransmitter Agents|Anti-Inflammatory Agents|Physiological Effects of Drugs|Sensory System Agents|Analgesics, Non-Narcotic|Anti-Inflammatory Agents, Non-Steroidal|Depressive Symptoms
Interventions: DRUG: VTS-K
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: StatStrip Lactate, Hemoglobin, and Hematocrit Meter in Whole Blood
Status: TERMINATED
Conditions: Sepsis|Anemia|Bleeding|Erythrocytosis
Interventions: DIAGNOSTIC_TEST: Lactate, Hemoglobin, Hematocrit
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lithium and Acetate for Canavan Disease
Status: WITHDRAWN
Conditions: Canavan Disease|Infantile|Deficiency Disease|Aspartoacylase|Leukodystrophy, Spongiform
Interventions: DRUG: Lithium Gluconate (drug) Glyceryl Triacetate GTA (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of JY09 on Pharmacokinetics of Metformin , Rosuvastatin , and Digoxin and the QT Interval Study in Overweight Chinese Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Overweight
Interventions: DRUG: Exendin-4 Fc fusion protein (JY09) injection|DRUG: Metformin Hydrochloride tablet|DRUG: Rosuvastatin calcium tablets|DRUG: Digoxin tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect and Mechanism of Social Interaction Treatment on ASD Children
Status: UNKNOWN
Conditions: ASD
Interventions: DEVICE: Social interaction treatment|DEVICE: Neuronal cognition treatment|OTHER: Routine treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain Control in AIS Using Liposomal Bupivacaine vs. 0.25% Bupivacaine With Epinephrine
Status: NOT_YET_RECRUITING
Conditions: Post Operative Pain|Spinal Fusion
Interventions: DRUG: Bupivacaine liposome injectable suspension|DRUG: Bupivacaine Hydrochloride and Epinephrine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Continuous Positive Airway Pressure (CPAP) on Hypertension and Cardiovascular Morbidity-Mortality in Patients With Sleep Apnea and no Daytime Sleepiness
Status: COMPLETED
Conditions: Sleep Apnea|Hypertension|Cardiovascular Diseases
Interventions: DEVICE: CPAP (Continuous Positive Airway Pressure)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of MBI 226 for the Prevention of Central Venous Catheter-Related Bloodstream Infections
Status: COMPLETED
Conditions: Sepsis|Bacteremia|Fungemia
Interventions: DRUG: MBI 226
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: CPAP vs AutoCPAP for Treatment of Obstructive Sleep Apnea (OSA) in the Postoperative Setting
Status: TERMINATED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Autoadjusting CPAP (VPAP Auto)|DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NEPH-ROSIS (NEPHrology in CirRhOSIS) Pilot Trial: A Trial to Treat Acute Kidney Injury Among Hospitalized Cirrhosis Patients
Status: RECRUITING
Conditions: Acute Kidney Injury|Cirrhosis|Portal Hypertension|Hepatorenal Syndrome|Acute Tubule Necrosis|Prerenal Failure
Interventions: DRUG: MAP-Target Algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Manual vs Instrument-assisted Manipulation on Electromyographic Activity and Sympathetic Nervous System
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Manual Manipulation|OTHER: Instrument-assisted Manipulation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Network Neurofeedback Using 7-Tesla MRI to Reduce Rumination Levels in Depression
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: Siemens 7T MRI|DEVICE: Sham Neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implant-supported Rehabilitation With SPAL Technique or Soft Tissue Augmentation
Status: RECRUITING
Conditions: Dehiscence|Alveolar Ridge Enlargement|Bone Loss, Alveolar
Interventions: PROCEDURE: Sub-Periosteal Peri-implant Augmented Layer technique|PROCEDURE: Soft tissue augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Naltrexone and Scopolamine Utilized in the Treatment of Major Depression
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Scopolamine and naltrexone|DRUG: placebo arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of Combination of Selinexor, Pomalidomide, and Dexamethasone (SPd) Versus Elotuzumab, Pomalidomide, and Dexamethasone (EloPd) in Subject With Previously Treated Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Selinexor|DRUG: Elotuzumab|DRUG: Pomalidomide|DRUG: Dexamethasone Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nitrate, Exercise and Vascular Function in Midlife Women
Status: NOT_YET_RECRUITING
Conditions: Healthy|Menopause|Hypertension|Inflammation
Interventions: DIETARY_SUPPLEMENT: Nitrate group|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Platelet Acetyl Coenzyme A Carboxylase Phosphorylation in Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease|Acute Coronary Syndrome|Coronary Thrombosis
Interventions: DIAGNOSTIC_TEST: Platelet Acetyl Coenzyme A Carboxylase analysis in CAD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Evaluation of the Effects of Home-based Functional Exercise on Patients With ACL
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Rupture|Rehabilitation
Interventions: BEHAVIORAL: Wechat application reminder intervention|BEHAVIORAL: routine guidance during discharge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: High-intensity Inspiratory Muscle Training in Patients With Asthma
Status: RECRUITING
Conditions: Asthma
Interventions: OTHER: High Intensity Inspiratory Muscle Training Group (H-IMT)|OTHER: Low Intensity Inspiratory Muscle Training Group (L-IMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Efficacy and Safety of Steroid Withdrawal With Tacrolimus and MMF With Induction in Children After Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: tacrolimus|DRUG: mycophenolate mofetil|DRUG: daclizumab|DRUG: steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Pharmacokinetics and Safety of HCP1306 and Co-administration of HGP0816, HGP1404 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Primary Hypercholesterolemia
Interventions: DRUG: HGP0816|DRUG: HGP1404|DRUG: HCP1306
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kinetics of Retinol and TBS Among Lactating Senegalese Women Living in an Urban Setting and the Relationship Between Their TBS and Those of Their Infants
Status: NOT_YET_RECRUITING
Conditions: Vitamin A
Interventions: OTHER: Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Physiotherapy Intervention in Climacteric Women With Dyspareunia
Status: COMPLETED
Conditions: Dyspareunia
Interventions: OTHER: superficial heat pelvic floor muscle|OTHER: superficial heat low back|OTHER: Pelvic Floor Muscle Training|OTHER: Manual therapy in iliopsoas, diaphragm and piriformis|OTHER: Intra Vaginal Manual therapy|OTHER: Electromyographic biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Guiding Hypertension Management Using Different Blood Pressure Monitoring Strategies
Status: UNKNOWN
Conditions: Hypertension
Interventions: DEVICE: uAOBP|DEVICE: Home BP|DEVICE: CBP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Anticariogenic Effect of Moringa Oleifera Mouthwash Compared to Chlorhexidine Mouthwash
Status: NOT_YET_RECRUITING
Conditions: Plaque, Dental|Antimicrobial|Mouthwash|Cytotoxicity
Interventions: DRUG: Moringa Oleifera|DRUG: Chlorhexidine mouthwash|DRUG: Base formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Evaluating Pain Outcomes of Caudal vs Ilioinguinal Nerve Block in Children Undergoing Hernia Repair
Status: UNKNOWN
Conditions: Hernia, Inguinal|Pain, Postoperative
Interventions: PROCEDURE: Ilioinguinal/iliohypogastric nerve block|PROCEDURE: Caudal-epidural nerve block|DRUG: Acetaminophen|DRUG: Sevoflurane|DRUG: Remifentanil|DRUG: Propofol|DRUG: Morphine|DRUG: Ondansetron|DRUG: Dexamethasone|DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Lertal® as an add-on to Standard Therapy for Allergic Rhinoconjunctivitis in Pediatrics
Status: COMPLETED
Conditions: Allergic Rhinoconjunctivitis
Interventions: DIETARY_SUPPLEMENT: Lertal® + standard therapy|OTHER: Placebo + standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Effect of Specialised Palliative Care on Symptoms, Survival, Economical Factors and Satisfaction
Status: COMPLETED
Conditions: Metastatic Cancer
Interventions: OTHER: Specialised palliative care (SPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Medico-economic Evaluation of Preoperative Cerebral Oximetry Monitoring During Carotid Endarterectomy
Status: TERMINATED
Conditions: Internal Carotid Stenosis
Interventions: OTHER: cerebral oximetry monitoring using INVOS™ and hemodynamic optimisation|OTHER: standard cerebral monitoring and hemodynamic optimisation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Compare the Bioavailability (BA) of Dexlansoprazole Delayed-release Capsules
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: 30 mg dexlansoprazole capsules manufactured at TOB|DRUG: 30 mg dexlansoprazole capsules manufactured at TPC|DRUG: 60 mg dexlansoprazole capsules manufactured at TOB|DRUG: 60 mg dexlansoprazole capsules manufactured at TPC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Telepalliation - Digital Platform for Patients in Palliation and Their Relatives
Status: RECRUITING
Conditions: Cancer|Heart Failure|Chronic Obstructive Pulmonary Disease|Neurological Diseases
Interventions: OTHER: Telepalliation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Iron and Zinc Supplementation on B-carotene Bioavailability in Healthy Males
Status: COMPLETED
Conditions: Bioavailability
Interventions: DIETARY_SUPPLEMENT: Control beta-carotene supplement plus Placebo|DIETARY_SUPPLEMENT: Control beta-carotene supplement plus iron Supplement|DIETARY_SUPPLEMENT: Control beta-carotene supplement plus zinc Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sitagliptin in Prevention of Type 2 Diabetes Mellitus
Status: WITHDRAWN
Conditions: Type 2 Diabetes
Interventions: DRUG: Sitagliptin|OTHER: life style modification at base line
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of SyB L-0501 to Treat Relapsed/Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: DRUG: SyB L-0501
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin for the Prophylaxis of Acute GVHD in Patients Undergoing Matched Sibling Allogeneic Transplantation
Status: COMPLETED
Conditions: Graft vs Host Disease
Interventions: DRUG: Atorvastatin calcium (Lipitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Aqueous Extract(Tea) of Euphorbia Hirta (Dudhiya) in Improving Sleep Quality
Status: COMPLETED
Conditions: Poor Sleep Quality
Interventions: OTHER: Euphorbia hirta (Dudhiya)|OTHER: PBO(Combined powder of Terminalia arjuna and Terminalia bellerica)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Injection of Human Placenta Mesenchymal Stem Cells Derived Exosomes for Treatment of Complex Anal Fistula
Status: RECRUITING
Conditions: Fistula Perianal
Interventions: OTHER: placenta-MSCs derived exosomes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Kinetic Study of Lp(a) and PCSK9 in Humans
Status: COMPLETED
Conditions: Cholesterol; Metabolic Disorder|Lipoproteinemia
Interventions: OTHER: infusion of tracer [5,5,5-2H3] -L-leucine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Auricular Acupuncture to Facilitate Outpatient Opioid Weaning
Status: TERMINATED
Conditions: Narcotic Addiction
Interventions: PROCEDURE: NADA Protocol|OTHER: Medication management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Air-polishing in the Treatment of Peri-implantitis
Status: ENROLLING_BY_INVITATION
Conditions: Peri-Implantitis
Interventions: PROCEDURE: Air-polishing|PROCEDURE: Mechanical decontamination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of UMSCs Derived Exosomes on Dry Eye in Patients With cGVHD
Status: UNKNOWN
Conditions: Dry Eye
Interventions: DRUG: Umbilical Mesenchymal Stem Cells derived Exosomes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole-Brain Radiation Therapy and Pemetrexed in Treating Patients With Brain Metastases From Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer|Metastatic Cancer
Interventions: DRUG: pemetrexed disodium|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Point-of-use Water Treatment Technologies to Prevent Stunting Among Children in South Africa
Status: UNKNOWN
Conditions: Diarrhoea;Infectious;Presumed|Diarrhea, Infantile|Diarrhea Tropical|Environmental Exposure|Enteropathy|Malnutrition, Child
Interventions: DEVICE: Silver-impregnated ceramic tablet|DEVICE: Silver-impregnated ceramic water filter|DEVICE: Safe-storage water container
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Adjuvant Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Versus no HIPEC in Locally Advanced Colorectal Cancer (APEC Study)
Status: UNKNOWN
Conditions: Locally Advanced Colorectal Cancer
Interventions: DRUG: Standard adjuvant systemic chemotherapy|PROCEDURE: Hyperthermic intraperitoneal chemotherapy (HIPEC) with raltitrexed|PROCEDURE: Hyperthermic intraperitoneal chemotherapy (HIPEC) with oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Free Mucogingival Graft for Isolated Root Coverage
Status: RECRUITING
Conditions: Free Mucogingival Grafts|Gingival Recession|Root Coverage|Periodontal Plastic Surgery
Interventions: PROCEDURE: Buccal muco-gingival tissue graft|PROCEDURE: Palatal connective tissue graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketotifen for Children With Functional Dyspepsia in Association With Duodenal Eosinophilia
Status: ACTIVE_NOT_RECRUITING
Conditions: Functional Dyspepsia
Interventions: DRUG: Ketotifen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Preoperative Transdermal Buprenorphine Patch in Reducing Postoperative Opioids Consumption in Patients Undergoing Total Knee Arthroplasties - A Randomised Controlled Trial.
Status: RECRUITING
Conditions: Patients Aged Between 18 and 65years Undergoing Total Knee Arthroplasty
Interventions: DRUG: Buprenorphine patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effectiveness of Combined Hyperthermia and External Beam Radiation (EBRT) Versus EBRT Alone in Treating Patients With Painful Bone Metastases
Status: UNKNOWN
Conditions: All Type of Cancers With Bony Metastasis
Interventions: OTHER: Hyperthermia|RADIATION: External-beam radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fibrin Based Adhesive for the Prevention of Surgical Complications in the Kidney Transplantation
Status: COMPLETED
Conditions: Vascular Postoperative Complications|Urological System Complication of Procedure|Lymphocele|Postoperative Infection
Interventions: BIOLOGICAL: Fibrin Glue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Optimizing Periconceptional and Prenatal Folic Acid Supplementation
Status: COMPLETED
Conditions: Pregnancy
Interventions: DRUG: PregVit® contains 1.1 mg of folic acid|DRUG: PregVit-folic 5® contains 5 mg of folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of the CUE1 in People With Parkinson's Disease and Related Disorders
Status: NOT_YET_RECRUITING
Conditions: Parkinson's Disease and Parkinsonism|Progressive Supranuclear Palsy|Tremor|Dystonia|Multiple System Atrophy|Corticobasal Degeneration|Vascular Parkinsonism
Interventions: DEVICE: CUE1 non-invasive device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Phase II Trial on Short Term Darolutamide Concomitant to Radiation Therapy for Patients With Intermediate Unfavorable Risk Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Association of darolutamide and EBRT|DRUG: Association of ADT and EBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improve Timely Referral Flow and Compliance of Diabetic Retinopathy Patients
Status: COMPLETED
Conditions: Diabetes|Diabetic Retinopathy
Interventions: BEHAVIORAL: Structured Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Short Message Service (SMS) Impact on Patient Compliance Receiving Long Term Lipid Lowering Therapy With Statins
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: OTHER: No intervention|BEHAVIORAL: Short Message Service (SMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficiency of Combined Rehabilitation Programs Including Resistance and Endurance Exercises on Functional Capacities, Quality of Life and Daily Level of Activities in Hemodialysis Patients
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Hemodialysis|Physical Rehabilitation
Interventions: OTHER: Combined rehabilitation during hemodialysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Placebo-controlled Study of L. Reuteri NCIMB 30351 in GI Functional Disorders and Food Allergy in Newborns
Status: COMPLETED
Conditions: Infantile Colic|Constipation|Infantile Diarrhea|Gastro Esophageal Reflux
Interventions: DIETARY_SUPPLEMENT: Lactobacillus Reuteri|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Respiratory-gated Stereotactic Body Radiation Therapy for Adenocarcinoma of the Pancreas or Periampullary Region
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: RADIATION: Stereotactic Body Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Cognitive Behavioral Approach-Based Stress Coping Skills Training Program on Stress Perception, Resilience and Compassion Fatigue
Status: RECRUITING
Conditions: Stress Perception, Psychological Resilience, Compassion Fatigue
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: T.R. Mobile Mental Health Support System produced by the Ministry of Health
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 3 Study of TAK-438 10 mg in the Treatment of Non-Erosive Gastroesophageal Reflux Disease (NERD)
Status: COMPLETED
Conditions: Non-erosive Gastroesophageal Reflux Disease
Interventions: DRUG: Placebo|DRUG: TAK-438 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SMOFLipid in Patients Who Are Intralipid Intolerant
Status: WITHDRAWN
Conditions: Home Parenteral Nutrition|Short Bowel Syndrome
Interventions: DRUG: SMOFLipid|DRUG: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine Tolerability of Single Increasing Dose of BIBN 4096 BS in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBN 4096 BS - in single rising doses|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Lavender Essential Oil Chest Wraps in Infants With Bronchiolitis
Status: RECRUITING
Conditions: Bronchiolitis
Interventions: DRUG: Lavender essential oil 10%, diluted in 90% olive oil|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AU409 for the Treatment of Advanced Primary Liver Cancers or Solid Tumor With Liver Metastatic Disease
Status: RECRUITING
Conditions: Advanced Cholangiocarcinoma|Advanced Hepatocellular Carcinoma|Advanced Malignant Solid Neoplasm|Metastatic Malignant Neoplasm in the Liver|Refractory Malignant Solid Neoplasm|Stage III Hepatocellular Carcinoma AJCC v8|Stage IV Hepatocellular Carcinoma AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: RNA Transcription Modulator AU-409
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Albuminuria Lowering Effect of Dapagliflozin, Spironolactone and Their Combination in Adult Patients with Alport Syndrome (COMBINE-ALPORT)
Status: RECRUITING
Conditions: Alport Syndrome|Thin Basement Membrane Disease|Alport Nephropathy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Denileukin Diftitox Used in Treating Patients With Advanced Refractory Ovarian Cancer, Primary Peritoneal Carcinoma, or Epithelial Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Clear Cell Cystadenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mixed Epithelial Carcinoma|Ovarian Mucinous Cystadenocarcinoma|Ovarian Serous Cystadenocarcinoma|Ovarian Undifferentiated Adenocarcinoma|Peritoneal Cavity Cancer|Recurrent Ovarian Epithelial Cancer|Stage III Ovarian Epithelial Cancer|Stage IV Ovarian Epithelial Cancer
Interventions: BIOLOGICAL: denileukin diftitox|PROCEDURE: intraperitoneal administration|OTHER: laboratory biomarker analysis|OTHER: enzyme-linked immunosorbent assay|OTHER: flow cytometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Finding Pediatric and Adult Trial With Sugammadex (Org 25969, MK-8616, SCH 900616) (19.4.306) (MK-8616-034) (P05961)
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Sugammadex 0.5 mg/kg|DRUG: Sugammadex 1 mg/kg|DRUG: Sugammadex 2 mg/kg|DRUG: Sugammadex 4 mg/kg|DRUG: Placebo|DRUG: Rocuronium bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study With Paliperidone ER Extended-Release (ER) Tablets in Geriatric Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: paliperidone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: MeDiGes Study: Metformine Use in Gestational Diabetes
Status: UNKNOWN
Conditions: Diabetes, Gestational|Perinatal Disorder|Puerperal Disorder
Interventions: DRUG: Metformin|DRUG: Insulin Detemir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of On-treatment ctDNA Changes in Chemo-refractory Colorectal Cancer Patients
Status: RECRUITING
Conditions: Unresectable Locally Advanced Colorectal Cancer|Metastatic Colorectal Cancer|Candidate for Third-line or Subsequent Lines of Therapy
Interventions: OTHER: Blood Sample Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Early Prediction of Therapeutic Response to Targeted Therapy in Stage IIIB/IV or Recurrent Lung Cancer Patients
Status: COMPLETED
Conditions: Cancer|Non Small Cell Lung Cancer
Interventions: RADIATION: PET Imaging|DRUG: Erlotinib|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized Study Comparing Two Dosing Schedules for Hypofractionated Image-Guided Radiation Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma|Ovarian Cancer|Sarcoma|Bone|CNS-Spinal CD/MEMBR, NOS|Lymph Nodes|Soft Tissue
Interventions: RADIATION: IGIMRT using a single dose of 24 Gy|RADIATION: IGIMRT 27 Gy in 3 fractions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-Finding Study of MK-1602 in the Treatment of Acute Migraine (MK-1602-006)
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: MK-1602|DRUG: Placebo-matching MK-1602|DRUG: Rescue medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Zoledronic Acid in the Treatment of Bone Metastases-related Pain in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Effects of Monochromatic Infrared Energy in Rehabilitation of Adolescents With Patellofemoral Pain Syndrome
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Monochromatic infrared energy|OTHER: Traditional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of pCLE and EB in Gastric Lesion Diagnosis
Status: RECRUITING
Conditions: Low Grade Intraepithelial Neoplasia|High Grade Intraepithelial Neoplasia|Early Gastric Cancer|Gastric Intraepithelial Neoplasia
Interventions: DEVICE: pCLE-gastr
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Exploratory Study of the Effect of Treatment Interruption on Safety of Exenatide in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: exenatide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Assessments of Potassium Nitrate in Polycarboxylate Versus Mineral Trioxide Aggregate as Pulpotomy Biomaterials in Immature Mandibular First Permanent Molars
Status: UNKNOWN
Conditions: Pulpotomy of Immature Lower First Molar(Apexegenesis)
Interventions: COMBINATION_PRODUCT: Potassium Nitrate in Polycarboxylate cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Submucosal Injection EMR vs. Underwater EMR for Colorectal Polyps
Status: COMPLETED
Conditions: Colonic Polyps|Rectal Polyps
Interventions: PROCEDURE: Submucosal Injection EMR|PROCEDURE: Underwater EMR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Effect of Preventive Use of Tylenol on Fever After Removal of Drainage Tube in Lumbar Fusion Surgery
Status: COMPLETED
Conditions: Lumbar Spinal Stenosis|Lumbar Disc Herniation|Lumbar Radiculopathy
Interventions: DRUG: Tylenol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Long-term Safety of Alpha1-Proteinase Inhibitor (Human) in Japanese Subjects With Alpha1 Antitrypsin Deficiency (GTI1401-OLE)
Status: COMPLETED
Conditions: Alpha1-Antitrypsin Deficiency
Interventions: BIOLOGICAL: Alpha-1 MP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy, Safety, Tolerability, and Pharmacokinetics of BIIB033 in Participants With Relapsing Forms of Multiple Sclerosis When Used Concurrently With Avonex
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: BIIB033|OTHER: Placebo|DRUG: Avonex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Benefits of a Multimodal Physiotherapy Programme in Fighter Pilots With Flight-related Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Cervical supervised exercises with laser-guided feedback (ELGF)|OTHER: Interferential current electro massage (ICE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: 18F-fluoride (18F-NaF) PET for Identifying Coronary Atherosclerotic Plaques
Status: COMPLETED
Conditions: Coronary Artery Disease|Atherosclerotic Plaque
Interventions: OTHER: 18F-NaF PET and coronary CTA imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Two-Stage Study to Assess the Efficacy and Safety of 12 Weeks of Treatment With PEP03 in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: UNKNOWN
Conditions: COPD
Interventions: DRUG: PEP03
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability, PK and PD of ABX1100
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: ABX1100 injection for IV infusion|DRUG: Placebo injection for IV infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Myocardial Ischemia: Troponin Monitoring,Cost-effectiveness, Insights Into Pathophysiology
Status: COMPLETED
Conditions: Myocardial Ischemia|Myocardial Injury|Morality
Interventions: OTHER: High sensitive Troponin T monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Validation of a Low-cost Platelet-Rich Plasma (PRP)
Status: ACTIVE_NOT_RECRUITING
Conditions: Platelet-Rich Plasma (PRP)|Knee Osteoarthritis (OA)
Interventions: PROCEDURE: Intra-Articular knee injection of LC-PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medical Treatment for Gastroesophageal Reflux Disease (GERD) in Preterm Infants
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: Metaclopramide|DRUG: Ranitidine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Angiotensin II Blockade and Inflammation in Obesity
Status: COMPLETED
Conditions: Overweight|Obese|Prehypertension|Hypertension
Interventions: DRUG: Olmesartan medoxomil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Effect of Aprepitant in Children and Adolescents Receiving AML Remission Induction Chemotherapy
Status: UNKNOWN
Conditions: Chemotherapy Induced Vomiting|Acute Myeloid Leukemia
Interventions: DRUG: Aprepitant|DRUG: Ondansetron|DRUG: Metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Intraoperative Physiologic Changes of Patients Under Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Cytoreductive Surgery; Prospective Observational Study
Status: COMPLETED
Conditions: Peritoneal Surface Malignancies
Interventions: DRUG: HIPEC cytoreductive surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Lumbal Lordosis and Thoracic Kyphosis Angles on Muscle Activations
Status: RECRUITING
Conditions: Low Back Pain, Postural
Interventions: OTHER: Thoracic kyphosis- Lumbal Lordosis angle measurement|OTHER: Back Muscle Endurance Test - Sorenson Test|OTHER: Surface EMG activation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination PET With 18F-fluorodeoxyglucose (18F-FDG) and 18 F-choline in Patient With HCC
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: PET-TDM with 18F-FDG + PET-TDM with 18F-fluorocholine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Assess Perfusion and Patient Satisfaction in Nipple-Areola Mastectomy With Immediate Reconstruction
Status: COMPLETED
Conditions: Ductal Carcinoma in Situ - Category|Breast Cancer|Prophylactic Mastectomy
Interventions: PROCEDURE: Inframammary Fold Incision or Lateral Radial Incision|PROCEDURE: Lateral Radial Incision|PROCEDURE: Inframammary Fold Incision|DEVICE: Laser-assisted fluorescence angiography|DRUG: Indocyanine Green
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Therapeutic Effect of Telitacicept on Lupus Erythematosus Complicated With Thrombocytopenia
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Telitacicept|DRUG: conventional therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Cannabidiol (CBD; GWP42003-P) for Infantile Spasms (GWPCARE7)
Status: COMPLETED
Conditions: Infantile Spasms
Interventions: DRUG: GWP42003-P
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Stereognosis in Completely Edentulous Patient With Maxillary Tori
Status: COMPLETED
Conditions: Torus Palatinus and Torus Mandibularis
Interventions: OTHER: oral stereognostic test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Evaluation of the Toffee Nasal Pillows Mask for the Treatment of Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Toffee Nasal Pillows Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT