pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Brivaracetam to Reduce Neuropathic Pain in Chronic Spinal Cord Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DRUG: Brivaracetam|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Sourdough Bread Consumption on Long-term Energy Intake: A Pilot Study of Feasibility
Status: RECRUITING
Conditions: Appetite Regulation|Energy Intake|Body Weight Changes|Eating Behavior|Overweight and Obesity
Interventions: OTHER: Dietary Intervention with Brown Bread|OTHER: Dietary Intervention with Sourdough Bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Lactobacillus Plantarum PS128 on the Parkinsonian Symptoms in Parkinson's Disease.
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DIETARY_SUPPLEMENT: PS128|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of GR68755 (Alosetron Hydrochloride) to Treat Severe Diarrhea-Predominant Irritable Bowel Syndrome (IBS)
Status: COMPLETED
Conditions: Irritable Colon
Interventions: DRUG: GR68755 (Alosetron hydrochloride) 1 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REnal reCOVery After ECMO for Cardiogenic Shock (RECOVECMO)
Status: COMPLETED
Conditions: Cardiogenic Shock|Renal Replacement Therapy|Venoarterial Extracorporeal Membrane Oxygenation
Interventions: OTHER: standard of care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hypertonic Saline 75% vs Mannitol 20%
Status: COMPLETED
Conditions: Brain Tumor|Tumor, Brain|Brain Neoplasm|Neoplasm, Supratentorial|Tumor, Supratentorial
Interventions: DRUG: Administration of Hypertonic Solution 7.5% vs Mannitol 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Acitretin in Preventing Skin Cancers in Patients With Previously Treated Skin Cancers Who Have Undergone Organ Transplantation
Status: COMPLETED
Conditions: Non-melanomatous Skin Cancer
Interventions: DRUG: acitretin|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Comparison of Elemental Liquid Diet and Standard Semi-solid Diet on Gastric Emptying
Status: COMPLETED
Conditions: Gastric Emptying
Interventions: OTHER: Elemental liquid diet|OTHER: Standard semi-solid diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: D-cycloserine for Relapse Prevention Following Intravenous Ketamine in Treatment-resistant Depression
Status: UNKNOWN
Conditions: Treatment Resistant Depression
Interventions: DRUG: Ketamine|DRUG: D-cycloserine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Renal Sympathetic Denervation Prevents Atrial Fibrillation in Patients With Hypertensive Heart Disease: a Pilot Study
Status: COMPLETED
Conditions: Hypertension|Hypertensive Heart Disease|Atrial Fibrillation|Autonomic Imbalance
Interventions: DEVICE: Renal denervation|DRUG: Medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Three-Dimensional Printed Customized Titanium Mesh for Mandibular Augmentation
Status: COMPLETED
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: 3D customized Titanium Mesh (Study)|PROCEDURE: Conventional ridge augmentation (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Common Meals on Appetite and Satiety
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: OTHER: lean steak and potatoes|OTHER: lentil and sweet potato chili|OTHER: macaroni and cheese|OTHER: fish tacos|OTHER: chicken and pea fried rice|OTHER: pita and hummus|OTHER: creamy pork pasta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Erythropoietin Effect on Ischemic_ Reperfusion Injury in Coronary Artery Bypass Graft Surgery
Status: COMPLETED
Conditions: Myocardial Ischemic Reperfusion Injury
Interventions: DRUG: normal saline|DRUG: erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: EUS-CNB Versus EUS-SINK for Diagnosis of Upper Gastrointestinal (UGI) Subepithelial Tumors
Status: TERMINATED
Conditions: Esophageal Subepithelial Lesions
Interventions: DEVICE: 22-gauge Procore needle (ProCore, Cook Medical Inc., Winston-Salem, NC)|DEVICE: conventional needle-knife sphincterotome (Microknife XL; Boston Scientific Inc, Natick, Mass)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Inotuzumab Ozogamicin in Treating Patients With Relapsed or Refractory CD22 Positive Acute Lymphoblastic Leukemia
Status: TERMINATED
Conditions: CD22 Positive|Recurrent Acute Lymphoblastic Leukemia|Refractory Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: Inotuzumab Ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Knee Arthroplasty and Clinical Findings
Status: COMPLETED
Conditions: Orthopedic Disorder|Arthropathy of Knee|Pain, Joint|Proprioception|Radiography
Interventions: PROCEDURE: Total Knee Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aerobic and Strengthening Exercise for Acute Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: OTHER: Gross Motor Function|OTHER: Knee extension strength|OTHER: Hand grip strength|OTHER: Flexibility|OTHER: Ankle range of motion|OTHER: Aerobic capacity|OTHER: Body composition and vital signs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Huperzine A in Treatment of Moderate to Severe TBI
Status: TERMINATED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Huperzine A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient
Status: COMPLETED
Conditions: Diabetic Ketoacidosis|Heart Disease, Ischemic|Stroke|GastroIntestinal Bleeding|Acute Kidney Injury|Heart Failure|Trauma|Septic Shock|Respiratory Failure|Pneumonia|Intracerebral Hemorrhage|Head Injury|Liver Diseases
Interventions: OTHER: relaxing music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Modified Docetaxel, Cisplatin, and Fluorouracil (mDCF) in Unresectable or Metastatic Gastric and Gastroesophageal Junction Adenocarcinoma
Status: COMPLETED
Conditions: Gastroesophageal Junction Adenocarcinoma|Gastric Cancer
Interventions: DRUG: Docetaxel, Leucovorin, Fluorouracil, Cisplatin|DRUG: Docetaxel, Cisplatin, Fluorouracil, Neulasta, or Neupogen|DRUG: Docetaxel, Leukvorin, Flurouracil, Cisplatin, Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Channel Interaction in Cochlear Implant and Speech Understanding in Noise
Status: COMPLETED
Conditions: Cochlear Implants
Interventions: OTHER: speech audiometry in noise|OTHER: Psychophysical tuning curves in forward masking|OTHER: Electrically-evoked Auditory Brainstem Response (EABR)|OTHER: Tonal audiometry|OTHER: Auditory canal examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Mirikizumab (LY3074828) in Children and Teenagers With Ulcerative Colitis (UC)
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Mirikizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Respiratory Outcomes After Early Vitamin D Supplementation in Infants Born Extremely Preterm
Status: RECRUITING
Conditions: Prematurity; Extreme
Interventions: DIETARY_SUPPLEMENT: Vitamin D supplementation|OTHER: No additional vitamin D supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nasal Carbon Dioxide (CO2) in the Symptomatic Treatment of Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Nasal CO2|DRUG: Inactive Placebo Gas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study to Compare the Safety and Effectiveness of NovoMix® 30 and Levemir™ for the Treatment of Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 30|DRUG: insulin detemir
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized, Double-blind, Dose-range-finding, Phase 2 Study of Linaclotide Administered to Patients With Irritable Bowel Syndrome With Constipation (IBS-C)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Constipation
Interventions: DRUG: Linaclotide Acetate|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Safety and Immunogenicity of a Prophylactic Plasmid DNA
Status: RECRUITING
Conditions: COVID-19
Interventions: DRUG: COVIGENIX VAX- 002
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Compare the Safety, Pharmacokinetics and Pharmacodynamics of HIP2105 to RLD2104 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: HIP2105|DRUG: RLD2104
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection
Status: RECRUITING
Conditions: Liver Cancer|Esophageal Cancer|Colorectal Cancer|Lung Adenocarcinoma|Control|Pancreas Cancer|Biliary Cancer
Interventions: DIAGNOSTIC_TEST: TEG indices
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Initial Experience With a Novel Single-Balloon Enteroscopy System in Children With IBD
Status: UNKNOWN
Conditions: Inflammatory Bowel Diseases|Colitis, Ulcerative|Crohn Disease
Interventions: DEVICE: NaviAid™ AB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Reducing Depressive Symptoms in Physically Ill Youth
Status: COMPLETED
Conditions: Inflammatory Bowel Disease|Depression
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Supportive Non-directive Therapy (SNDT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial
Status: RECRUITING
Conditions: Neurofibromatosis 1|Noonan Syndrome|Legius Syndrome|Cardiofaciocutaneous Syndrome|Costello Syndrome
Interventions: BEHAVIORAL: Waitlist|BEHAVIORAL: ACT Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Thoracic Spinal Anesthesia in Awake Breast Surgery
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: spinal group|OTHER: paravertebral group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: EEG and SEP Evaluation for Good and Poor Neurological Prognosis After Cardiac Arrest
Status: COMPLETED
Conditions: Neurological Prognosis Cardiac Arrest
Interventions: DIAGNOSTIC_TEST: Neurophysiological Prognosis|DIAGNOSTIC_TEST: Multimodal Prognosis for poor early neurological outcome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Open Label Extension to SRE Studies in United Kingdom and Czech Republic Only
Status: COMPLETED
Conditions: Bone Metastases in Men With Hormone-Refractory Prostate Cancer|Bone Metastases in Subjects With Advanced Breast Cancer|Bone Metastases in Subjects With Advanced Cancer or Multiple Myeloma
Interventions: DRUG: amg 162
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunevasion of Human Papillomavirus (HPV) in Vulvar Intraepithelial Neoplasia 2/3 and Anogenital Warts and Efficiency and Mechanisms of Imiquimod Treatment
Status: COMPLETED
Conditions: HPV
Interventions: DRUG: Imiquimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of 18F-ALF-NOTA-PRGD2 PET/CT Scan to Predict the Efficacy and Adverse Events of Apatinib in Malignancies.
Status: COMPLETED
Conditions: Malignancies|Stomach Cancer|Non-small Cell Lung Cancer|Esophageal Cancer|Breast Cancer|Ovary Cancer|Cervical Cancer
Interventions: DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis
Status: RECRUITING
Conditions: Systemic Sclerosis|Diffuse Sclerosis Systemic|Interstitial Lung Disease|Pulmonary Hypertension
Interventions: DRUG: Cyclophosphamide|DRUG: Mesna|DRUG: Rituximab|DRUG: Alemtuzumab|DRUG: Thiotepa|DRUG: GM-CSF|DRUG: Intravenous immunoglobulin|RADIATION: Total Body Irradiation|DRUG: Anti Thymocyte Globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Agaricus Blazei (Murrill) ss. Heinemann (Sun Mushroom)
Status: COMPLETED
Conditions: Hepatitis C|Nutritional Status|Hepatitis, Viral, Human
Interventions: DIETARY_SUPPLEMENT: Agaricus blazei (Murrill) ss. Heinemann (sun mushroom)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Single-task Versus Dual-task Training on balancePERFORMANCE
Status: COMPLETED
Conditions: Balance Impairment
Interventions: OTHER: single task balance training|OTHER: dual task balance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TAK-438 - Safety, Blood Levels & Effects of Repeated Doses
Status: COMPLETED
Conditions: Erosive Esophagitis(EE)|Gastroesophageal Reflux Disease (GERD)
Interventions: DRUG: TAK-438|DRUG: TAK-438 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 3 Study of Siltuximab or Placebo in Combination With Velcade and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: Placebo, Velcade and dexamethasone|BIOLOGICAL: Siltuximab, Velcade and dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: e-Mobile Tablet for People With Chronic Conditions
Status: COMPLETED
Conditions: Fibromyalgia|Multiple Sclerosis|Osteoarthritis|Sjögren's Syndrome|Parkinson's Disease
Interventions: BEHAVIORAL: Computer Tablet Group|BEHAVIORAL: Paper and Pencil Group|BEHAVIORAL: Contact Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Misoprostol Vaginal Insert (MVI) 100, 150, 200 mcg for Cervical Ripening and Induction of Labor
Status: COMPLETED
Conditions: Cervical Ripening|Induction of Labor
Interventions: DRUG: MVI 100|DRUG: MVI 150|DRUG: MVI 200
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Penn State TXT2STAYQUIT Study- a Texting Study to Help Hospitalized Smokers Stay Quit
Status: TERMINATED
Conditions: Nicotine Dependence, Cigarettes
Interventions: BEHAVIORAL: Motivational Text Messages|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Efficacy, Pharmacokinetics, and Safety of Repeat Subcutaneous Doses of FB825 in Adults With Moderate-to-Severe Atopic Dermatitis
Status: NOT_YET_RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: FB825|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IGFBP-2 Vaccine and Combination Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Undergoing Surgery
Status: TERMINATED
Conditions: Stage III Fallopian Tube Cancer|Stage III Ovarian Cancer|Stage III Primary Peritoneal Cancer|Stage IIIA Fallopian Tube Cancer|Stage IIIA Ovarian Cancer|Stage IIIA Primary Peritoneal Cancer|Stage IIIB Fallopian Tube Cancer|Stage IIIB Ovarian Cancer|Stage IIIB Primary Peritoneal Cancer|Stage IIIC Fallopian Tube Cancer|Stage IIIC Ovarian Cancer|Stage IIIC Primary Peritoneal Cancer|Stage IV Fallopian Tube Cancer|Stage IV Ovarian Cancer|Stage IV Primary Peritoneal Cancer
Interventions: DRUG: Carboplatin|PROCEDURE: Gynecological Surgical Procedure|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|BIOLOGICAL: pUMVC3-hIGFBP-2 Multi-Epitope Plasmid DNA Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Contact Lens Drug Delivery System (TCL-DDS) in Patients With Recurrent Cystoid Macular Edema
Status: RECRUITING
Conditions: Cystoid Macular Edema
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Infraclavicular and Interscalen Block on Oxygenitaon of the Forearm
Status: COMPLETED
Conditions: Upper Extremity Fracture
Interventions: PROCEDURE: Infraclavicular Block|PROCEDURE: Interscalen Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Physiological and Thermoregulatory Responses of Body Cooling During Cycling in a Hot Environment
Status: COMPLETED
Conditions: Hyperthermia
Interventions: OTHER: Forearm coolng|OTHER: Wet-towel cooling|OTHER: mist-fan|OTHER: passive cooling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Delish Study: Diabetes Education to Lower Insulin, Sugars, and Hunger
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Carbohydrate-restricted diet|BEHAVIORAL: Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: INtegrating DEPrEssioN and Diabetes treatmENT (INDEPENDENT) Study
Status: COMPLETED
Conditions: Diabetes|Depression|Cardiovascular Risk Factor
Interventions: BEHAVIORAL: Patient Education and Behavioral Activation|BEHAVIORAL: Supporting Self-Care (care coordinators)|OTHER: Psychiatrist and Diabetologist Reviews|OTHER: Decision-support Electronic Health Record System|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Retinal Changes in Vitamin D Deficiency
Status: COMPLETED
Conditions: Pediatric Disorder|Vitamin D Deficiency|Retinal Disease|Choroidal Disease|Optic Nerve Diseases
Interventions: DIETARY_SUPPLEMENT: Vitamin D deficiency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of DAC Combined With HAAG Regimen in Newly Diagnosed AML Patients Older Than 60
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|Induction Chemotherapy
Interventions: DRUG: Decitabine, Homoharringtonine, Aclarubicin, Cytarabine and G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance Evaluation of an Advanced Algorithm With CGM in Adults, Adolescents, and Pediatrics
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Type2 Diabetes Mellitus
Interventions: DEVICE: Guardian™ Sensor (3) connected to a Guardian™ Connect Transmitter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PD-1 Antibody, Chidamide, Lenalidomide and Etoposide for Relapsed or Refractory NK/T Cell Lymphoma
Status: UNKNOWN
Conditions: NK/T Cell Lymphoma
Interventions: DRUG: PD-1 Antibody, chidamide, lenalidomide and etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Electrical Stimulation Via the Peroneal Nerve Reduces Muscle Soreness Following Intermittent Exercise
Status: COMPLETED
Conditions: Delayed Onset Muscle Soreness
Interventions: OTHER: control|DEVICE: graduated compression socks|DEVICE: neuromuscular electrical stimulation device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL)
Status: RECRUITING
Conditions: B-Cell Non-Hodgkin's Lymphoma (NHL)|Lymphoma, Non-Hodgkins|Lymphomas Non-Hodgkin's B-Cell|Non-Hodgkin Lymphoma|Non-Hodgkin's Lymphoma|Large B-Cell Lymphoma|Lymphoma, Non-Hodgkin's, Adult|Lymphoma|Refractory Non-Hodgkin Lymphoma|Relapsed Non-Hodgkin Lymphoma|Lymphoma, Non-Hodgkin|HIV Associated Lymphoma|CNS Lymphoma|High-grade B-cell Lymphoma|Refractory B-Cell Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: EB103
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Antibiotics After Functional Endoscopic Sinus Surgery: a Randomized, Double-blind Placebo Controlled Trial
Status: COMPLETED
Conditions: Sinusitis
Interventions: DRUG: Amoxicillin-Potassium Clavulanate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wound Healing of Incisional Wounds for Bilateral Hernia Repair
Status: WITHDRAWN
Conditions: Wound Healing
Interventions: DRUG: Dermabond|DRUG: Hydrogen Peroxide Oxygen producing gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tolvaptan/Ultrafiltration in the Treatment of Acute Heart Failure
Status: COMPLETED
Conditions: Acute Decompensated Heart Failure
Interventions: DRUG: loop diuretic|DRUG: tolvaptan|PROCEDURE: ultrafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Intranasal Ketamine for the Treatment of Obsessive-Compulsive Disorder
Status: TERMINATED
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: Ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Letrozole and Trilostane for Medical Abortion
Status: TERMINATED
Conditions: Medical Abortion, Complete or Unspecified, Without Complication
Interventions: DRUG: Letrozole|DRUG: Trilostane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Two Osteopathic Techniques for the Hamstring's Stretching Capacity in Basketball Female Players
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: OTHER: Simulated technique|OTHER: Muscle energy technique|OTHER: 4th ventricle technique and muscular energy technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Monolithic Zirconia With CAD/CAM Titanium Abutments: A 5-year Prospective Case Series Study
Status: NOT_YET_RECRUITING
Conditions: Edentulous Alveolar Ridge
Interventions: DEVICE: Astra Tech Osseospeed EV® dental implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability, and Efficacy of Lecanemab in Subjects With Early Alzheimer's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer's Disease
Interventions: DRUG: Lecanemab 2.5 mg/kg|DRUG: Lecanemab 5.0 mg/kg|DRUG: Lecanemab 10 mg/kg|DRUG: Lecanemab 5.0 mg/kg|DRUG: Lecanemab 10 mg/kg|DRUG: Placebo|DRUG: Lecanemab 10 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Pharmacokinetics and Drug Interaction Liability of Kratom, an Opioid-like Natural Product
Status: COMPLETED
Conditions: Interaction Drug Food
Interventions: DRUG: Midazolam HCl|DRUG: Dextromethorphan HBr|DIETARY_SUPPLEMENT: Kratom
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: RAS Peptide Profiles in Patients With Arterial Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Perindopril|DRUG: Olmesartan|DRUG: Amlodipine|DRUG: Hydrochlorothiazide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: RCT of Cast or Functional Ankle Orthosis After Ankle Fracture Surgery
Status: COMPLETED
Conditions: Ankle Fracture|Postoperative Treatment
Interventions: DEVICE: 2-week casting followed by 4-week bracing|DEVICE: 6-week casting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 64Cu-SAR-BBN for Identification of Participants With Recurrence of Prostate Cancer (SABRE)
Status: COMPLETED
Conditions: Biochemical Recurrence of Malignant Neoplasm of Prostate
Interventions: DRUG: 64Cu-SAR-BBN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tramadol Extended-Release (ER) for Posttraumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: DRUG: Tramadol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cross-over Study to Evaluate the Safety and Efficacy of Night Closed-loop Control Using the MD-Logic Automated Insulin Delivery System Compared to Sensor Augmented Pump Therapy in Poorly Controlled Patients With Type 1 Diabetes
Status: WITHDRAWN
Conditions: Type 1 Diabetes
Interventions: DEVICE: MD- Logic Closed Loop System|DEVICE: sensor augmented pump therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Clinical Trial of Tenoten for Children Liquid Dosage Form Therapy in Infants With Sequelae of Perinatal Brain Injury
Status: COMPLETED
Conditions: Sequelae of Perinatal Brain Injury
Interventions: DRUG: Tenoten for children|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Apatinib Combined With Chemotherapy in the Treatment of Soft Tissue Sarcoma
Status: UNKNOWN
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Apatinib Mesylate, Pirarubicin, Ifosfamide|DRUG: Apatinib Mesylate|DRUG: Pirarubicin, Ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ART0380 in Patients With Biologically Selected Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|Recurrent Endometrial Cancer|Metastatic Cancer
Interventions: DRUG: ART0380
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Prebiotics and/or Probiotics on Uremic Toxins and Inflammation Markers in Peritoneal Dialysis Patients
Status: UNKNOWN
Conditions: End Stage Renal Failure on Dialysis
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Prebiotic|DIETARY_SUPPLEMENT: Symbiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tissue Sample Collection From Patients With Soft Tissue Sarcoma of the Arms, Hands, Legs, or Feet Treated on Clinial Trial CRUK-VORTEX
Status: UNKNOWN
Conditions: Sarcoma
Interventions: GENETIC: microarray analysis|GENETIC: molecular diagnostic method|OTHER: biologic sample preservation procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: S0702: Osteonecrosis of the Jaw in Patients With Cancer Receiving Zoledronic Acid for Bone Metastases
Status: COMPLETED
Conditions: Breast Cancer|Lung Cancer|Metastatic Cancer|Multiple Myeloma|Plasma Cell Neoplasm|Prostate Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: PROCEDURE: assessment of therapy complications
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Repurposed Drugs to Improve Haematological Responses in Myelodysplastic Syndromes
Status: RECRUITING
Conditions: Myelodysplastic Syndromes (MDS)
Interventions: DRUG: Sodium Valproate, Bezafibrate, Medroxyprogesterone|DRUG: Danazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ib Study of Safety, Tolerability and Pharmacokinetics of Elpida Once Weekly in Healthy Volunteers
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: Elpida|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: On the Safety, Tolerability, and Efficacy of UTAA09 Injection in the Treatment of Lymphoma
Status: RECRUITING
Conditions: Recurrent or Refractory B-cell Non Hodgkin's Lymphoma
Interventions: BIOLOGICAL: UTAA09 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Comparison of Patellofemoral Pain Syndrome Outcomes After Blood Flow Restriction Therapy
Status: TERMINATED
Conditions: Patellofemoral Pain Syndrome|Anterior Knee Pain Syndrome
Interventions: DEVICE: Blood Flow Restriction Cuff|PROCEDURE: Sham and standard of Care Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enzalutamide With or Without Radium Ra 223 Dichloride in Patients With Metastatic, Castration-Resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Prostate Carcinoma Metastatic in the Bone|Stage IV Prostate Cancer
Interventions: DRUG: Enzalutamide|OTHER: Laboratory Biomarker Analysis|RADIATION: Radium Ra 223 Dichloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Application of EBUS and EUS in Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: PROCEDURE: EUS-B-FNA followed by EBUS-TBNA|PROCEDURE: EBUS-TBNA followed by EUS-B-FNA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: PRObiotic VSL#3® for Maintenance of Clinical and Endoscopic REMission in Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: VSL#3®|DRUG: Mesalamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Metabolic Cost of Medicine Ball Training
Status: COMPLETED
Conditions: Body Composition|Physical Fitness|Energy Expenditure|Resting Metabolic Rate
Interventions: BEHAVIORAL: MB-TB|BEHAVIORAL: MB-NTB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Prehabilitation Care for Women With Advanced Ovarian Cancer Receiving Neoadjuvant Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer|Stage III Ovarian Cancer|Stage IV Ovarian Cancer|Primary Peritoneal Carcinoma|Fallopian Tube Carcinoma|Fallopian Tube Cancer
Interventions: OTHER: Prehabilitation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Alternative Dosing for CRLX101(NLG207) Alone, With Avastin and With mFOLFOX6 in Advanced Solid Tumors
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: CRLX101|DRUG: Bevacizumab|DRUG: mFOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety And Efficacy of the Transradial Coronary in Comparison With the Transfemoral Coronary Intervention
Status: UNKNOWN
Conditions: Free Rate of Cardiac or Cerebrovascular Events|Transradial-transfemoral Coronary Interventions Comparison
Interventions: PROCEDURE: Transradial Coronary Intervention|PROCEDURE: Transfemoral Coronary Intervention|DEVICE: Coronary Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lapatinib Combined With Paclitaxel For Patients With First-Line ErbB2-Amplified Metastatic Breast Cancer
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: Lapatinib oral tablets|DRUG: Paclitaxel infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of a HABIT-ILE Intervention at Home for Chronic Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: BEHAVIORAL: Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) implemented at the patient home|BEHAVIORAL: Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE)|BEHAVIORAL: Follow-up Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) at the patient's home|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Durvalumab With Consolidative Radiochemotherapy and Ablative Stereotactic Radiotherapy in Oligometastatic ES-SCLC
Status: RECRUITING
Conditions: Extensive-stage Small-cell Lung Cancer
Interventions: RADIATION: Thoracic Radiochemotherapy|DRUG: durvalumab|RADIATION: Stereotactic radiotherapy of further tumor locations|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Selective Laser Trabeculoplasty Versus Travoprost on Circardian Intraocular Pressure
Status: COMPLETED
Conditions: Intraocular Pressure
Interventions: DEVICE: Selective laser trabeculoplasty|DRUG: Travoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial to Describe the Safety, Tolerability, and Immunogenicity of Trumenba When Administered to Immunocompromised Participants ≥10 Years of Age
Status: COMPLETED
Conditions: Meningococcal Vaccine
Interventions: BIOLOGICAL: Trumenba
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Immunochemotherapy for LAOSCC
Status: RECRUITING
Conditions: Oral Squamous Cell Carcinoma|Locally Advanced Head and Neck Carcinoma
Interventions: DRUG: albumin paclitaxel, cispatin, tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate Efficacy and Safety of Rivaroxaban 15mg and 20mg in Patients With Non-valvular Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation|Anticoagulant Adverse Reaction
Interventions: DRUG: Rivaroxaban 20 MG|DRUG: Rivaroxaban 15 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT of the Clinical and Cost Effectiveness of Cognitive Behaviour Therapy (CBT) Delivered Remotely Versus Treatment as Usual in Adolescents and Young Adults With Depression Who Repeatedly Self-harm
Status: COMPLETED
Conditions: Depression and Self-Harm
Interventions: BEHAVIORAL: Problem solving cognitive behaviour therapy (PS CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Rivoceranib Plus Best Supportive Care Compared to Placebo Plus Best Supportive Care in Participants With Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer|Gastric Adenocarcinoma
Interventions: DRUG: Rivoceranib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dressing Versus Glue (2-Octyl Cyanoacrylate) for Coverage of the Skin Incision After Closure During Cesarean Delivery
Status: WITHDRAWN
Conditions: Pregnant Women|Cesarean Section
Interventions: DEVICE: 2-octyl cyanoacrylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Clinical Study of Asciminib in Previously Treated Indian Patients With Ph+ CML-CP Without T315I Mutation and in Patients With Ph+ CML-CP With T315I Mutation
Status: NOT_YET_RECRUITING
Conditions: Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase
Interventions: DRUG: Asciminib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics ，Pharmacodynamics of Oral SHR2150 in Healthy Subjects
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: SHR2150；Placebo|DRUG: SHR2150；Placebo|DRUG: SHR2150；Placebo|DRUG: SHR2150；Placebo|DRUG: SHR2150；Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Clinical Effects of Hard and Soft Tissue Grafting With Dental Implants
Status: COMPLETED
Conditions: Dental Implants
Interventions: DEVICE: Dental Implant &ADMG|DEVICE: Dental implant & ADMG & BDX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incidence of Urinary Retention in Patients Undergoing Unilateral Total Knee Arthroplasty- Comparison Between Continuous Epidural Analgesia and Single Shot Femoral Nerve Block- a Randomized Controlled Study (UriKANE)
Status: COMPLETED
Conditions: Acute Pain|Urinary Retention|Post Operative Pain
Interventions: PROCEDURE: Femoral Nerve Block|PROCEDURE: Epidural
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Bendamustine Plus Rituximab Versus CHOP Plus Rituximab
Status: COMPLETED
Conditions: Non-Hodgkin Lymphomas|Follicular Lymphomas|Immunocytomas|Lymphocytic Lymphomas|Marginal Zone Lymphomas
Interventions: DRUG: Bendamustine|DRUG: Standard chemotherapy CHOP + Ritiximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Extensive Clinical Target Volumes in Postoperative Radiotherapy Concurrent With Chemotherapy for Esophageal Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Syndrome, Bile Acids, Hepatocellular Carcinoma and Cholangiocarcinoma
Status: COMPLETED
Conditions: Morbid Obesity|Vertical Sleeve Gastrectomy|Metabolic Syndrome|Hepatocellular Carcinoma|Cholangiocarcinoma|Disorder of Bile Acid and Cholesterol Metabolism
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Remediation of Age-related Cognitive Decline: Vortioxetine and Cognitive Training
Status: COMPLETED
Conditions: Age-related Cognitive Decline
Interventions: DRUG: Vortioxetine 10 mg|BEHAVIORAL: Cognitive training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-arterial Thrombolysis for Severe Recent Central Retinal Vein Occlusion
Status: COMPLETED
Conditions: Central Retinal Vein Occlusion
Interventions: DRUG: Tissue Plasminogen Activator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Purified Anthocyanins Supplementation in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus，Type 2
Interventions: DIETARY_SUPPLEMENT: Anthocyanin|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Subjects With Newly Diagnosed High Grade Glioma Receiving Standard of Care
Status: WITHDRAWN
Conditions: Newly Diagnosed High Grade Glioma (HGG)
Interventions: BIOLOGICAL: Toca 511|DRUG: Toca FC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the Distal Radial Approach
Status: UNKNOWN
Conditions: Vascular Access Complication|Coronary Artery Disease
Interventions: PROCEDURE: distal radial artery approach|PROCEDURE: conventional radial artery approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combined Physical and Psychological Intervention in Carpal Tunnel Syndrome Patients With Nociplastic Pain
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome|Pain, Chronic
Interventions: OTHER: Combined physical and psychological intervention|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of NGR-hTNF as Single Agent in Patients Affected by Advanced or Metastatic Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: NGR-hTNF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of New Intermittent Single-use Catheter
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DEVICE: Investigational device - newly developed intermittent catheter|DEVICE: Comparator device #1 - SpeediCath Eve|DEVICE: Comparator device #2 - SpeediCath Compact Plus Female
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION