pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of Insulin Glargine and Regular Insulin Versus NPH and Regular Insulin in the Treatment of T1DM
Status: COMPLETED
Conditions: To Assess the Glycemic Control of Insulin Glargine in Combination With Regular Insulin in Type 1 Diabetes in Children
Interventions: DRUG: Glargine and regular insulin versus NPH and regular insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Mindfulness Intervention to the Timing of Labor Admission, Uncertainty and Anxiety
Status: COMPLETED
Conditions: Anxiety|Uncertain Viability of Pregnancy
Interventions: BEHAVIORAL: Mindfulness training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Psychoeducation on Motivation to Change in Traumatized Alcoholics
Status: COMPLETED
Conditions: Alcoholic Intoxication, Chronic
Interventions: BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 3D Geplante Osteosynthesen Mit Patientenspezifischen Zielvorrichtungen
Status: TERMINATED
Conditions: Fracture of Humerus|Fracture of Ulna Radius|Fracture of Clavicle|Fracture of Hand|Fracture of Pelvis|Fracture of Femur|Fracture of Tibia Fibula|Fracture of Skull
Interventions: DEVICE: fracture fixation with patient specific guides|DEVICE: standard procedure of fracture fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Effectiveness of NXN-188 for the Acute Treatment of Migraine Attacks With Aura
Status: UNKNOWN
Conditions: Migraine With Aura
Interventions: DRUG: NXN-188|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylaxis of Magnesium-rich Mineral Water to Prevent Hypomagnesemia Induced by an Anti-EGFR (OPTIMAG)
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer|Metastatic Head and Neck Cancer
Interventions: OTHER: Magnesium-rich mineral water (Rozana)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cognitive Ability Training in Seniors
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: Verum tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N-acetylcysteine (NAC) for Improving Cognitive Dysfunction in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: N-acetylcysteine (NAC)|DRUG: Inactive placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Posterior Versus Lateral Transversus Abdominis Plan Block for Prolonged Postoperative Analgesic Effect in Children
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: PROCEDURE: postoperative analgesia for lower abdominal surgery in children
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: HFCWO in Prolonged Mechanical Ventilation Patients
Status: COMPLETED
Conditions: Chronic Ventilator Dependency
Interventions: DEVICE: HFCWO (Hill-Rom Vest™ Airway Clearance System)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Intervention for Polycystic Ovary Syndrome: Pulse-Based Diet and Exercise
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Metabolic Syndrome
Interventions: OTHER: Pulse-based diet|OTHER: TLC diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2127399 in Participants With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus|Connective Tissue Disease|Autoimmune Disease
Interventions: DRUG: LY2127399|DRUG: Placebo every 2 weeks|DRUG: Placebo every 4 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nevirapine Study for the Prevention of Maternal-Infant HIV Transmission in Uganda
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nevirapine|DRUG: HIV immune globulin solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability Study of 2 Dose Level of Arikayce™ in Patients With Bronchiectasis and Chronic Infection Due to Pseudomonas Aeruginosa.
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: DRUG: 280 mg Arikayce™|DRUG: Matching Placebo for Cohort 1|DRUG: 560 mg Arikayce™|DRUG: Matching Placebo for Cohort 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the H-Coil Transcranial Magnetic Stimulation (TMS) Device in the Treatment of Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Depression
Interventions: DEVICE: H1 -coil TMS device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Coadministration of Sotorasib on the Pharmacokinetics of Rosuvastatin in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Rosuvastatin|DRUG: Sotorasib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Rostafuroxin in the Treatment of Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Rostafuroxin|DRUG: Rostafuroxin|DRUG: Rostafuroxin|DRUG: Rostafuroxin|DRUG: Rostafuroxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cluster Randomized Controlled Screening Trial for NPC
Status: ACTIVE_NOT_RECRUITING
Conditions: Nasopharyngeal Cancer|Screening|Morality
Interventions: DIAGNOSTIC_TEST: Experimental: Screening with EBV VCA/EBNA1-IgA testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Clinical Trial to Evaluate the Safety and Efficacy of "AG1904" in Acute Bronchitis
Status: COMPLETED
Conditions: Acute Bronchitis
Interventions: DRUG: AGS (Experimental)|DRUG: AGU (Active Comparator)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pharmacodynamics and Safety of DGAT2i and ACCi Coadministered in Participants With Sponsor-defined Presumed Non Alcoholic Steatohepatitis
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis|Nonalcoholic Fatty Liver Disease
Interventions: DRUG: PF-06865571|DRUG: PF-05221304|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Study of Non-Invasive Assessment of Hepatic And Myocardial Iron Through T2* Magnet Resonance Imaging (MRI) In Patients With Iron Overload
Status: COMPLETED
Conditions: Hematological Diseases
Interventions: PROCEDURE: Liver Biopsy and MRI T2* MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Role of Inflammatory Markers and Doppler Parameters in Late-Onset Fetal Growth Restriction: A Machine Learning Approach
Status: ACTIVE_NOT_RECRUITING
Conditions: Fetal Growth Restriction|Inflammatory Response
Interventions: DIAGNOSTIC_TEST: Ultrasound measurement|DIAGNOSTIC_TEST: Laboratory Tests and Inflammatory Markers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Recombinant Asparaginase in Infants With Previously Untreated Acute Lymphoid Leukemia (ALL)
Status: COMPLETED
Conditions: Acute Lymphoid Leukemia
Interventions: DRUG: recombinant asparaginase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Contact Aspiration Versus Stent Retriever for Acute Basilar Artery Occlusion
Status: RECRUITING
Conditions: Basilar Artery Occlusion|Endovascular Treatment
Interventions: PROCEDURE: Contact aspiration Thrombectomy|PROCEDURE: Stent retriever thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incisional Hernia Repair Long-term Outcomes
Status: COMPLETED
Conditions: Incisional Hernia
Interventions: PROCEDURE: Laparoscopic incisional ventral hernia repair|PROCEDURE: Open incisional ventral hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptance and Commitment Therapy as a New Treatment for Adults With Insomnia Disorder
Status: COMPLETED
Conditions: Insomnia Chronic
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy plus Sleep Restriction|BEHAVIORAL: Cognitive Behavioral Therapy including Sleep Restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Rupatadine 5, 10 and 20 mg in Chronic Idiopathic Urticaria
Status: TERMINATED
Conditions: URTICARIA
Interventions: DRUG: Rupatadine Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CD19 CAR T Cells in Patients With Relapsed or Refractory CD19 Positive B-cell Lymphoma
Status: COMPLETED
Conditions: Lymphomas Non-Hodgkin's B-Cell|Relapse
Interventions: BIOLOGICAL: CD19 CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Letetresgene Autoleucel Engineered T Cells Alone and in Combination With Pembrolizumab in NY-ESO-1 Positive Multiple Myeloma
Status: TERMINATED
Conditions: Neoplasms
Interventions: DRUG: Letetresgene autoleucel|DRUG: Letetresgene autoleucel with pembrolizumab|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Oral Fampridine-Sustained Release (SR) for the Treatment of Spasticity Resulting From Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury|Muscle Spasticity
Interventions: DRUG: Fampridine-SR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Recipients With Limited Bimodal Benefit: HA or CROS
Status: UNKNOWN
Conditions: Cochlear Implant|Hearing Disability|Hearing Disorders and Deafness
Interventions: DEVICE: Naida Hearing Aid|DEVICE: Naida Contralateral Routing of Sound Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Cinacalcet in Pediatric Patients With Secondary Hyperparathyroidism (SHPT) and Chronic Kidney Disease (CKD) on Dialysis
Status: TERMINATED
Conditions: Chronic Kidney Disease, Secondary Hyperparathyroidism
Interventions: DRUG: Cinacalcet HCl|DIETARY_SUPPLEMENT: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aspirin for Exercise in Multiple Sclerosis (ASPIRE)
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Aspirin 650mg Oral Capsule|DRUG: Acetaminophen Tablet 650mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bortezomib, Rituximab, and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Relapsed or Refractory Low-Grade, Follicular, or Mantle Cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: bortezomib|RADIATION: yttrium Y 90 ibritumomab tiuxetan|RADIATION: Indium 111 ibritumomab tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 17-Alpha-Hydroxyprogesterone Caproate in Pregnant Women With Placenta Previa
Status: UNKNOWN
Conditions: Placenta Previa
Interventions: DRUG: 17-OHPC|DRUG: placebo to 17-OHPC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Seven vs. 14 Days Treatment for Male Urinary Tract Infection
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: OTHER: Longer therapy duration|OTHER: Shorter therapy duration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of Mechanism of Chronic Insomnia Disorder Using Acupuncture Based on Changes of Brain GABA and fMRI
Status: UNKNOWN
Conditions: Insomnia Disorder
Interventions: PROCEDURE: ture acupuncture|PROCEDURE: sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Escitalopram Treatment for BPSD in Alzheimer's Disease in Comparison to Risperidone
Status: COMPLETED
Conditions: Agitation|Psychosis|Alzheimer's Disease
Interventions: DRUG: Escitalopram|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nitrous Oxide- Suicidal Ideation
Status: ENROLLING_BY_INVITATION
Conditions: Major Depressive Disorder|Depression|Mood Disorders|Suicidal Ideation
Interventions: DRUG: Nitrous Oxide|DRUG: Placebo gas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Adolescents With CBT and OBH
Status: TERMINATED
Conditions: Anxiety Disorders|Depressive Disorder|Substance Use Disorders
Interventions: BEHAVIORAL: Outdoor Behavioral Healthcare (OBH)|BEHAVIORAL: Cognitive Behavioral Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: RELAXaHEAD for Headache Patients (Phase III)
Status: RECRUITING
Conditions: Migraine
Interventions: BEHAVIORAL: RELAXaHEAD Smartphone App Version 1|BEHAVIORAL: RELAXaHEAD Smartphone App Version 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A 2 Part Study Examining Doses Of GSK961081 In Healthy Volunteers And Then In COPD Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK961081
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: CRISIS2: A Phase 2 Study of the Safety and Antiviral Activity of Brequinar in Non-hospitalized Pts With COVID-19
Status: COMPLETED
Conditions: COVID-19 Infection
Interventions: DRUG: Brequinar|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROBE Parallel 6-week Treatment Comparing Telmisartan/Hydrochlorothiazide (HCT) (40/12.5 or 80/12.5) With Losartan/HCT (50/12.5) Using Ambulatory Blood Pressure Monitoring (ABPM)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan & Hydrochlorothiazide|DRUG: Losartan & Hydrochlorothiazide|PROCEDURE: ABPM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Oxytocin Receptor Immunoreactivity in Placentas Obtained From Women Having Cesarean and Natural Birth
Status: COMPLETED
Conditions: Healthy Mothers Who Have Had Both Vaginal and Cesarean Deliveries
Interventions: OTHER: The delivery being performed via cesarean section surgery rather than natural childbirth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Testing the Feasibility of Using Ropivacaine in Spinal Anesthesia for Patients With Lower Back Surgery
Status: NOT_YET_RECRUITING
Conditions: Anesthesia, Spinal|Neurosurgery|Ropivacaine|Bupivacaine
Interventions: DRUG: Spinal anesthesia for lumbar surgery: ropivacaine|DRUG: Spinal anesthesia for lumbar surgery: bupivacaine|DRUG: General anesthesia for lumbar surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Chili Pepper Extract on Weight and Fat Loss and Metabolism Increase
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DIETARY_SUPPLEMENT: Chronic consumption of chili pepper extract|DIETARY_SUPPLEMENT: Chronic consumption of matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Different Weekly Frequency of Modified Pilates Method Exercises in the Treatment of Chronic Nonspecific Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DEVICE: Pilates 1|DEVICE: Pilates 2|DEVICE: Pilates 3|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: General Anesthesia Versus Awake Surgery in Resection of Gliomas and Metastases of Motor Areas
Status: RECRUITING
Conditions: Gliomas Benign|Glioma, Malignant|Metastases to Brain
Interventions: PROCEDURE: Tumor resection in awake patient|PROCEDURE: Tumor resection in asleep patient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of Pneumococcal Vaccines in Ataxia-telangiectasia Patients
Status: UNKNOWN
Conditions: Ataxia Telangiectasia
Interventions: BIOLOGICAL: Prevenar® (7-valent pneumococcal conjugate vaccine)|BIOLOGICAL: Pneumovax® (pneumococcal polysaccharide vaccine)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sym004 Versus Futuximab or Modotuximab in Patients With mCRC
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer|Colorectal Cancer Metastatic|Carcinoma
Interventions: DRUG: Sym004|DRUG: Futuximab|DRUG: Modotuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of V0251 in Acute Vertigo
Status: COMPLETED
Conditions: Acute Vertigo
Interventions: DRUG: V0251|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effect of Short-term Fasting on T Cell Metabolism, Function, and Phenotype in Obesity
Status: NOT_YET_RECRUITING
Conditions: Obesity|Fasting|T-Cell Dysfunction
Interventions: OTHER: Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: First-in-Human Single Ascending Dose of SHR0302
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: SHR0302|DRUG: SHR0302 placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Beta-thalassemia and Microparticles
Status: COMPLETED
Conditions: Thalassemia Major (TM)|Thalassemia Intermedia (TI)|Microparticles (MP)Originating From Platelets, Endothelial Cells and Monocytes
Interventions: OTHER: Physiopathology|OTHER: Physiopathology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Clinical and Radiological Evaluation of Meniscal Healing After Percutaneous Intra-meniscal Injection of Platelet-rich Plasma (PRP)
Status: COMPLETED
Conditions: Meniscus Lesion
Interventions: PROCEDURE: Intra-meniscal injection of platelet-rich plasma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial of SHR-1701 in Combination With Famitinib in Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Solid Tumor
Interventions: BIOLOGICAL: SHR-1701|DRUG: Famitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Safety and Preliminary Efficacy of DCC-2036 in Patients With Leukemias (Ph+ CML With T315I Mutation)
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: DCC-2036
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Trial of GEN1042 in Japanese Subjects With Malignant Solid Tumors
Status: RECRUITING
Conditions: Malignant Solid Tumor
Interventions: BIOLOGICAL: GEN1042|DRUG: Pembrolizumab|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of ACE-031 (ActRIIB-IgG1)in Healthy Postmenopausal Volunteers
Status: COMPLETED
Conditions: Muscle Loss
Interventions: BIOLOGICAL: ACE-031
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Graft-Versus-Host Disease in Patients Undergoing Bone Marrow Transplantation
Status: COMPLETED
Conditions: Cancer
Interventions: BIOLOGICAL: graft versus host disease prophylaxis/therapy|PROCEDURE: allogeneic bone marrow transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Almonertinib Plus Microwave Ablation in Advanced Non-small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced Non Small Cell Lung Cancer
Interventions: COMBINATION_PRODUCT: Almonertinib plus microwave ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protein and Magnesium in Ulcerative Colitis
Status: UNKNOWN
Conditions: Inflammatory Bowel Diseases|Colitis, Ulcerative|Magnesium Deficiency|Nutritional Deficiency|Protein Deficiency
Interventions: DIETARY_SUPPLEMENT: Magnesium acetate mixture (30 mmol/ml)|DIETARY_SUPPLEMENT: High-protein diet (2 g/kg/day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DN-101 in Combination With Docetaxel in Androgen-Independent Prostate Cancer (AIPC) (AIPC Study of Calcitriol Enhancing Taxotere [ASCENT-2])
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: calcitriol|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cangrelor Versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition.
Status: TERMINATED
Conditions: Atherosclerosis|Acute Coronary Syndrome (ACS)
Interventions: DRUG: Cangrelor|DRUG: clopidogrel|DRUG: Placebo bolus & placebo infusion|DRUG: Placebo capsules - end of PCI|DRUG: Placebo capsules - end of infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aumolertinib Adjuvant Therapy of Resectable Stage I EGFRm+ NSCLC With High-grade Patterns
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Aumolertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of TLK286 Administered Weekly in Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-small-cell Lung
Interventions: DRUG: TLK286
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1 Antibody Adjuvant Therapy for GC Patients With MSI-H After D2 Radical Surgery
Status: NOT_YET_RECRUITING
Conditions: MSI-H|PD-1 Immunotherapy|Gastric Cancer|Adjuvant Therapy
Interventions: DRUG: SOX|DRUG: XELOX|OTHER: Observation|DRUG: PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Depression in Parkinson's Disease Trial
Status: COMPLETED
Conditions: Parkinson Disease|Depression
Interventions: DRUG: paroxetine|DRUG: Nortriptyline|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pivotal Study of the Al-Sense Study Protocol
Status: COMPLETED
Conditions: Amniotic Fluid Leakage
Interventions: DEVICE: AL-SENSE Diagnostic Absorbent Panty liner|DEVICE: AL-SENSE Diagnostic Absorbent Panty liner
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A (FRONTIER 4)
Status: RECRUITING
Conditions: Haemophilia A|Haemophilia A With Inhibitors
Interventions: DRUG: Mim8
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rebif® Versus Copaxone® in the Treatment of Relapsing Remitting Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: DRUG: Rebif®|DRUG: Copaxone®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tissue-nonspecific Alkaline Phosphatase in Phosphate and Pyrophosphate Homeostasis.
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: OTHER: Blood samples|OTHER: Urinary samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Study Between Autogenous Bone Block and Tent Pole Technique for Augmentation of Atrophic Anterior Maxilla
Status: RECRUITING
Conditions: Bone Atrophy, Alveolar
Interventions: PROCEDURE: tent pole technique|PROCEDURE: Autogenous bone block technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Interference With Cognitive Control by Transcranial Direct Current Stimulation
Status: COMPLETED
Conditions: Depression
Interventions: DEVICE: Cathodal transcranial direct current stimulation (tDCS)|DEVICE: Sham transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate Safety, Pharmacokinetics and Anti-Tumor Activity of RO7300490, as Single Agent or in Combination With Atezolizumab in Participants With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: RO7300490|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Yoghurt Containing Four Probiotic Lactobacillus Strains on Bacterial Vaginosis
Status: COMPLETED
Conditions: Bacterial Vaginosis
Interventions: OTHER: probiotic yoghurt|OTHER: chemically acidified milk|DRUG: Arilin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acute Transcranial Direct Current Stimulation in Patients With Systemic Autoimmune Myopathies
Status: RECRUITING
Conditions: Myopathy|Neurologic Manifestations|ElectroPhys: Myopathy
Interventions: OTHER: Transcranial direct current stimulation session.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: An Exploratory Study of Atezolizumab and Bevacizumab in Hepatocellular Carcinoma and Non-Small Cell Lung Cancer With Liver Metastases (INTEGRATE)
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Non-small Cell Lung Cancer Metastatic|Liver Metastases
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Friction Massage: Symptomatic
Status: COMPLETED
Conditions: Tendinopathy
Interventions: OTHER: DFM: Mean pressure|OTHER: DFM: Mean pressure - 25%|OTHER: DFM: Mean pressure + 25%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparative Pharmacokinetics Study of Clopidogrel and Aspirin Fixed-dose Combination Versus Separate Combination
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Clopidogrel|DRUG: Fixed dose combination of clopidogrel/Aspirin|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research on the Brain Mechanism of taVNS in Regulating PD Motor Symptoms
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Transcutaneous auricular vagus nerve stimulation (active）|DEVICE: Transcutaneous auricular vagus nerve stimulation (sham）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Inherited Factor VII Deficiency
Status: COMPLETED
Conditions: Factor VII Deficiency
Interventions: DRUG: plasma derived Factor VII|DRUG: recombinant FVIIa|DRUG: Fresh Frozen Plasma|DRUG: Activated Prothrombin Complex Concentrates|DRUG: Virus Inactivated plasma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Chimeric Antigen Receptor T Lymphocytes for Patients With Intermediate and Advanced Tumors
Status: UNKNOWN
Conditions: Melanoma|Non-small Cell Lung Cancer|Head and Neck Squamous Cell Carcinoma
Interventions: BIOLOGICAL: AMT-116 CAR-T cells|BIOLOGICAL: AMT-253 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Trial of Stribild for Antiretroviral (ARV)-naïve HIV-2 Infected Adults in Dakar, Senegal
Status: COMPLETED
Conditions: HIV-2 Infection
Interventions: DRUG: Stribild (Elvitegravir/Cobicistat/Emtricitabine/Tenofovir DF) 1 tablet daily X 48 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of ThermaCare Heat Wraps and Ibuprofen as an Adjunct to Physical Therapy for Neck Pain
Status: COMPLETED
Conditions: Heat|Pain
Interventions: DEVICE: thermacare heat wraps|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation in Hemodialysis Patients
Status: COMPLETED
Conditions: Complication of Dialysis|Chronic Kidney Disease|Muscle Loss|End Stage Renal Disease
Interventions: DIETARY_SUPPLEMENT: HMB|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: A Study Using Rapid Acting Intramuscular Olanzapine in Agitated Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: olanzapine-RAIM|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of the Misoprostol Vaginal Priming Insert (MVPI) Prior to Hysteroscopy
Status: COMPLETED
Conditions: Cervical Priming
Interventions: DRUG: misoprostol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Therapy for Vasculogenesis in Patients With Severe Myocardial Ischemia
Status: COMPLETED
Conditions: Myocardial Ischemia|Coronary Heart Disease
Interventions: BIOLOGICAL: stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addressing Palliative Care Needs Among Intensive Care Unit Family Members
Status: COMPLETED
Conditions: Critical Illness|Family Members|Psychological Distress|Informal Caregivers|Palliative Care
Interventions: BEHAVIORAL: Needs-focused mobile app|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing Aloe Vera Gel and Rosemary Oil in Pressure Injury Prevention
Status: RECRUITING
Conditions: Pressure Injury
Interventions: COMBINATION_PRODUCT: Aloe Vera rosemary tropical application|COMBINATION_PRODUCT: aloevera tropical application|COMBINATION_PRODUCT: rosemary tropicalapplication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study on the Application of Hyperspectral Imaging Technique in the Treatment of IMN by TAC
Status: NOT_YET_RECRUITING
Conditions: Idiopathic Membranous Nephropathy|Tacrolimus|Hyperspectral Imaging
Interventions: DRUG: Tacrolimus for the treatment of IMN
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Non-Comparative Study of Fluconazole in Patients With Serious Mycoses and Who Cannot Be Treated With Conventional Antifungal Therapy
Status: COMPLETED
Conditions: Candidiasis|Mycoses|HIV Infections
Interventions: DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Amsterdam UMC Clinical Trial With a Native-like HIV-1 Envelope Vaccine
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: BIOLOGICAL: ConM SOSIP.v7 gp140, adjuvanted with MPLA liposomes|BIOLOGICAL: ConM SOSIP.v7 gp140, adjuvanted with MPLA liposomes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Possible Protective Role of Ketotifen Against Oxaliplatin Induced Peripheral Neuropathy
Status: RECRUITING
Conditions: Neuropathy;Peripheral
Interventions: DRUG: Placebo tablets|DRUG: Ketotifen Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Remote Monitoring With Health-Coaching for Lifestyle Changes in Patients With Lung Cancer Related Fatigue
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lung Non-Small Cell Carcinoma|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: OTHER: Exercise Counseling|OTHER: Exercise Intervention|OTHER: Internet-Based Intervention|OTHER: Interview|OTHER: Medical Device Usage and Evaluation|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Redox Regulation of Satellite Cells and Skeletal Muscle Healing
Status: COMPLETED
Conditions: Satellite Cells|Redox Status|Exercise-induced Muscle Trauma|Aseptic Inflammation
Interventions: DIETARY_SUPPLEMENT: N-Acetylcysteine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Endobiliary Radiofrequency Ablation With S-1 for Unresectable Cholangiocarcinoma
Status: COMPLETED
Conditions: Cholangiocarcinoma
Interventions: DEVICE: radiofrequency ablation|DRUG: S-1|DEVICE: Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects on Pes Planus Exercise Training Mixed With Play on Pre-school Children
Status: COMPLETED
Conditions: Pes Planus|Flat Foot|Femoral Anteversion
Interventions: BEHAVIORAL: Exercise Training Mixed With Play|OTHER: Controlled
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QoL After Complex Endovascular Aortic Repair
Status: RECRUITING
Conditions: Quality of Life|Aortic Aneurysm|Aortic Aneurysm, Abdominal
Interventions: PROCEDURE: Standard Endovascular aneurysm repair (sEVAR)|PROCEDURE: Complex Endovascular Aneurysm Repair (cEVAR)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gliadel Wafer, Temozolomide and Radiation Therapy for Newly Diagnosed GBM
Status: TERMINATED
Conditions: Glioblastoma Multiforme|High-Grade Glioma
Interventions: DRUG: Gliadel wafer|DRUG: Temozolomide|RADIATION: External Beam Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic of GSK1070806 After a Single Intravenous Dose in Healthy Male and Female Caucasian, Chinese and Japanese Participants Aged 18 to 65 Years of Age Inclusive
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: GSK1070806|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Shift-and-persist and Cardiometabolic Markers Among Women in Puerto Rico
Status: COMPLETED
Conditions: Psychological Distress|Cardiometabolic Syndrome
Interventions: BEHAVIORAL: Mindfulness-based Stress reduction program: Virtual|BEHAVIORAL: Home exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Perineural Versus Systemic Dexamethasone to Prolong Regional Anesthesia in Front Foot Surgery
Status: COMPLETED
Conditions: Pain Management After Surgery
Interventions: DRUG: Dexamethasone|DRUG: isotonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Trial of SyB L-0501 in Combination With Rituximab to Patients With Aggressive B-cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Diffuse Large B-Cell Lymphoma|Mantle Cell Lymphoma|Follicular Lymphoma
Interventions: DRUG: SyB L-0501|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate GSK Biologicals' GSK2197870A Vaccine Given as Primary Course in Infants
Status: COMPLETED
Conditions: Neisseria Meningitidis|Haemophilus Influenzae Type b
Interventions: BIOLOGICAL: GSK2197870A|BIOLOGICAL: Prevenar™|BIOLOGICAL: Menitorix™|BIOLOGICAL: Pediacel™|BIOLOGICAL: Menjugate™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Surveillance vs. Anticoagulation for Low-risk Patients With Isolated Subsegmental Pulmonary Embolism
Status: RECRUITING
Conditions: Pulmonary Embolism|Embolism|Embolism and Thrombosis|Lung Diseases|Cardiovascular Diseases|Respiratory Tract Diseases|Venous Thromboembolism|Anticoagulant-induced Bleeding|Bleeding
Interventions: DRUG: Rivaroxaban|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Hyperpure Chlorine Dioxide and Sodium Hypochlorite Irrigants in Endodontic Retreament in RCT
Status: ENROLLING_BY_INVITATION
Conditions: Persistent Infection|Periapical Lesion
Interventions: OTHER: endodontic desinfection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of JMT103 in the Treatment of Postmenopausal Women With Osteoporosis
Status: UNKNOWN
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: JMT103|DRUG: Denosumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Collaborative and Adaptive Recommender for Personalized DIEt Management
Status: COMPLETED
Conditions: Diet Habit|Sleep|Life Style, Healthy|Physical Activity
Interventions: DEVICE: Mobile app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Thyme Honey in The Management of Oral Aphthous Ulcers
Status: NOT_YET_RECRUITING
Conditions: Aphthous Stomatitis (Major) (Minor)|Treatment Compliance
Interventions: OTHER: Thyme honey|DRUG: Kenalog
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing the Efficacy and Safety of DE-127 Ophthalmic Solution in Subjects With Mild or Moderate Myopia (APPLE)
Status: COMPLETED
Conditions: Myopia
Interventions: DRUG: DE-127 Ophthalmic Solution low dose|DRUG: DE-127 Ophthalmic Solution medium dose|DRUG: DE-127 Ophthalmic Solution high dose|DRUG: Placebo Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interactive Care Plan for the Monitoring of Symptoms and Recovery in Patients With Stage 0-III Breast Cancer
Status: COMPLETED
Conditions: Anatomic Stage 0 Breast Cancer AJCC v8|Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Training in HFpEF-PH
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Hypertension Due to Left Heart Disease|Heart Failure With Preserved Ejection Fraction
Interventions: OTHER: Exercise rehabilitation|OTHER: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Gain Information How Well Dexpanthenol Dermal Spray Helps the Face Skin to Recover After Cosmetic Lasering
Status: COMPLETED
Conditions: Erythema|Skin Recovery
Interventions: DRUG: BAY207543 (Bepanthol, Bepantol® Derma Spray)|OTHER: Semisolid vaseline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Post Market Clinical Follow-up (PMCF) Study of the A.L.P.S. Proximal Humerus Plating System
Status: RECRUITING
Conditions: Osteoarthritis|Rheumatoid Arthritis|Post-Traumatic Arthritis|Psoriatic Arthritis|Proximal Humeral Fracture
Interventions: DEVICE: A.L.P.S. Proximal Humerus Plating System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Passive and Active ROM Exercises Following TKA
Status: COMPLETED
Conditions: Osteoarthritis|Total Knee Arthroplasty
Interventions: OTHER: continuous passive motion (CPM)|OTHER: controlled active motion (CAM I)|OTHER: controlled active motion (CAM II)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of the Effect of Lactulose on Post Caesarean Section Constipation
Status: UNKNOWN
Conditions: Constipation|Abdominal Pain|Nausea|Vomiting
Interventions: DRUG: Lactulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT