pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of a New Radiotracer (64Cu-DOTA-AE105) for Diagnosing Aggressive Cancer With Positron Emission Tomography
Status: COMPLETED
Conditions: Breast Cancer|Prostate Cancer|Urinary Bladder Cancer
Interventions: OTHER: Injection of 64Cu-DOTA-AE105
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: External Ankle Supports - 3D Motion Analysis
Status: COMPLETED
Conditions: Chronic Ankle Instability
Interventions: DEVICE: Applying ankle support device (white non-elastic tape, kinesiotape (TM), soft brace (Malleotrain TM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Synbiotic on Postoperative Complications After Liver Transplantation
Status: UNKNOWN
Conditions: Liver Disease
Interventions: DIETARY_SUPPLEMENT: Synbiotic|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Narrow-band Imaging, Autofluorescence Imaging and Gastroesophageal Reflux Disease
Status: UNKNOWN
Conditions: Gastroesophageal Reflux Disease
Interventions: OTHER: symptom questionaire|PROCEDURE: pH monitoring|PROCEDURE: Tri-modal imaging endoscopy|DRUG: rabeprazole
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access
Status: RECRUITING
Conditions: End Stage Renal Disease (ESRD)|Kidney Failure|Chronic Renal Disease
Interventions: DEVICE: InnAVasc arteriovenous graft surgical implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Effect of Rifampicin on the Pharmacokinetics of Eribulin Mesylate in Participants With Advanced Solid Tumors
Status: COMPLETED
Conditions: Tumor
Interventions: DRUG: Eribulin mesylate|DRUG: Eribulin mesylate|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-finding of Multiple Dose of BT061 in Patients With Active Rheumatoid Arthritis Incompletely Controlled on Stable Methotrexate (MTX)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: BT061|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dyadic-Based Diagnosis, Care, and Prevention for HIV Discordant Couples in Tanzania
Status: COMPLETED
Conditions: HIV
Interventions: BEHAVIORAL: HIV Self-Testing|BEHAVIORAL: Immediate Access to ART for HIV infected couple members|BEHAVIORAL: Access to PrEP for HIV uninfected couple members
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Target Volume Delineation After NACT in LA-NPCarcinoma Patients Treated With NACT+ CCRT
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: RADIATION: Target Volume Delineation after NACT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness vs. Support Groups for Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: BEHAVIORAL: Mindfulness training|BEHAVIORAL: Psycho-educational support group for women with IBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Stimulation in Elderly Individuals at Risk to Develop Dementia (Allena-Mente).
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Healthy Subjects With Family History for Dementia
Interventions: OTHER: Cognitive stimulation|OTHER: Sanitary education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional and Neuroprotective Effects of Restoring Lower Limb Sensation After Diabetic Peripheral Neuropathy
Status: RECRUITING
Conditions: Lower Extremity Amputee|Diabetic Peripheral Neuropathy
Interventions: DEVICE: Implanted Multi contact stimulating electrode and intramuscular electromyography recording electrode
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Efficacy and Safety Trial to Evaluate the Effect of SCH 497079 on Weight in Obese and Overweight Participants (Study P05483)(COMPLETED)
Status: COMPLETED
Conditions: Obesity|Overweight|Body Weight
Interventions: DRUG: SCH 497079|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SMART Program for Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation|Stress
Interventions: OTHER: SMART Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Behavioral and Physiological Effects of Cocaine in Cocaine-dependent Participants Treated With Levodopa in Combination With Carbidopa and Entacapone (LCE)
Status: COMPLETED
Conditions: Cocaine Abuse
Interventions: DRUG: L-dopa / carbidopa / entacapone (LCE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Control Trial of Fluid Therapy for Pediatric Diabetic Ketoacidosis
Status: COMPLETED
Conditions: Cerebral Edema|Diabetic Ketoacidosis
Interventions: DRUG: 0.45% saline replacement fluid|DRUG: 0.9% saline replacement fluid|DRUG: 0.45% saline intravenous fluid|DRUG: 0.9% saline Intravenous fluid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Autologous Adipose Tissue-Derived Mesenchymal Progenitor Cells (MPCs) Therapy for Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Mesenchymal progenitor cells|BIOLOGICAL: Sodium Hyaluronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study of Prophylactic Gastrostomy in Head and Neck Cancer Patients Undergoing Chemoradiotherapy
Status: TERMINATED
Conditions: Carcinoma, Squamous Cell of Head and Neck
Interventions: PROCEDURE: prophylactic percutaneous gastrostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Type 2 Diabetes (T2D) Basal Insulin Users: The Mobile Study (MOBILE)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: Dexcom G6 CGM System|DEVICE: Blood glucose meter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Gastrografin in the Management of Fecal Impaction in Patients With Severe Chronic Constipation
Status: UNKNOWN
Conditions: Fecal Impaction
Interventions: DRUG: Gastrograﬁn|PROCEDURE: enemas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preemptive Analgesic Effects of Popliteal Sciatic Nerve Block in Patients With Bilateral Hallux Valgus Surgery
Status: UNKNOWN
Conditions: Pain, Postoperative|Preemptive Peripheral Nerve Block|Acute Pain
Interventions: DRUG: Ultrasound guided popliteal sciatic nerve block with 0.2% ropivcaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Blueberries on Immunity and Response to Flu Vaccination
Status: ACTIVE_NOT_RECRUITING
Conditions: Immune Response|Inflammation
Interventions: DIETARY_SUPPLEMENT: Blueberry powder group|DIETARY_SUPPLEMENT: Placebo powder group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Protecting the Corneal Endothelium During Cataract Surgery Using the Anterior Capsule
Status: COMPLETED
Conditions: Endothelial Cell Loss, Corneal
Interventions: PROCEDURE: Rhexis protection shield
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bovine Intestinal Alkaline Phosphatase (bIAP) Modulating Rheumatoid Arthritis
Status: COMPLETED
Conditions: Acute Rheumatoid Arthritis
Interventions: DRUG: s.c. injections of bovine intestinal Alkaline Phosphatase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Gemcitabine and Cisplatin With or Without Cetuximab in Urothelial Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: Gemcitabine,|DRUG: Cisplatin|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Brain Structure Related to Systemic Chemotherapy Treatment: A Prospective Study in Individuals Diagnosed With Non-small Cell Lung Cancer Utilizing High-resolution Structural Magnetic Resonance Imaging
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: OTHER: MRI Screening Form, MRI, Demographic / Medical Data form|OTHER: MRI Screening Form, MRI. Demographic / Medical Data
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fatty Liver in Obesity: Long-lifestyle Follow-up (FLiO)
Status: UNKNOWN
Conditions: Non-Alcoholic Fatty Liver Disease|Obese|Overweight
Interventions: OTHER: Control diet|OTHER: FLiO diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Lapatinib Plus Trastuzumab or Lapatinib Plus Capecitabine in Metastatic Breast Cancer
Status: WITHDRAWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Lapatinib plus trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intravenous Ibuprofen Compared to Intravenous Ketorolac for Pain Control Following Arthroscopic Knee Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: IV ibuprofen|DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dead Space in Mechanical Ventilation With Constant Expiratory Flow
Status: NOT_YET_RECRUITING
Conditions: Mechanical Ventilation|Artificial Respiration
Interventions: DEVICE: Flow-controlled ventilation (FCV)|DEVICE: Conventional volume-controlled ventilation (VCV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sorafenib Therapy Prior to Radiofrequency Ablation for Intermediate Sized Hepatocellular Cancer
Status: COMPLETED
Conditions: Hepatocellular Cancer
Interventions: DRUG: Sorafenib|PROCEDURE: radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2, Open-Label Study for Safety, Microbiology and PK of Single or Multiple Oral C16G2 Gel Doses
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: C16G2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity, Safety and Reactogenicity Study of GlaxoSmithKline (GSK) Biologicals' Hib-MenCY-TT (MenHibrix®) Vaccine Compared to Merck & Co, Inc. PedvaxHIB Vaccine in Healthy Infants and Toddlers 12 to 15 Months of Age
Status: COMPLETED
Conditions: Neisseria Meningitidis|Haemophilus Influenzae Type b
Interventions: BIOLOGICAL: Hib-MenCY-TT (MenHibrix®)|BIOLOGICAL: Pediarix®|BIOLOGICAL: Rotarix®|BIOLOGICAL: Prevnar 13®|BIOLOGICAL: PedvaxHIB®|BIOLOGICAL: Havrix®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ketone Pharmacokinetic Study in HFrEF
Status: COMPLETED
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: DIETARY_SUPPLEMENT: DeltaG (250 mg/kg)|DIETARY_SUPPLEMENT: DeltaG (500 mg/kg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: AR-42 in Treating Patients With Advanced or Relapsed Multiple Myeloma, Chronic Lymphocytic Leukemia, or Lymphoma
Status: COMPLETED
Conditions: Adult Nasal Type Extranodal NK/T-cell Lymphoma|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Cutaneous B-cell Non-Hodgkin Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Hepatosplenic T-cell Lymphoma|Intraocular Lymphoma|Nodal Marginal Zone B-cell Lymphoma|Peripheral T-cell Lymphoma|Post-transplant Lymphoproliferative Disorder|Prolymphocytic Leukemia|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Multiple Myeloma|Stage III Adult Burkitt Lymphoma|Stage III Adult Diffuse Large Cell Lymphoma|Stage III Adult Diffuse Mixed Cell Lymphoma|Stage III Adult Diffuse Small Cleaved Cell Lymphoma|Stage III Adult Hodgkin Lymphoma|Stage III Adult Immunoblastic Large Cell Lymphoma|Stage III Adult Lymphoblastic Lymphoma|Stage III Adult T-cell Leukemia/Lymphoma|Stage III Chronic Lymphocytic Leukemia|Stage III Cutaneous T-cell Non-Hodgkin Lymphoma|Stage III Grade 1 Follicular Lymphoma|Stage III Grade 2 Follicular Lymphoma|Stage III Grade 3 Follicular Lymphoma|Stage III Mantle Cell Lymphoma|Stage III Marginal Zone Lymphoma|Stage III Multiple Myeloma|Stage III Mycosis Fungoides/Sezary Syndrome|Stage III Small Lymphocytic Lymphoma|Stage IV Adult Burkitt Lymphoma|Stage IV Adult Diffuse Large Cell Lymphoma|Stage IV Adult Diffuse Mixed Cell Lymphoma|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma|Stage IV Adult Hodgkin Lymphoma|Stage IV Adult Immunoblastic Large Cell Lymphoma|Stage IV Adult Lymphoblastic Lymphoma|Stage IV Adult T-cell Leukemia/Lymphoma|Stage IV Chronic Lymphocytic Leukemia|Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma|Stage IV Grade 1 Follicular Lymphoma|Stage IV Grade 2 Follicular Lymphoma|Stage IV Grade 3 Follicular Lymphoma|Stage IV Mantle Cell Lymphoma|Stage IV Marginal Zone Lymphoma|Stage IV Mycosis Fungoides/Sezary Syndrome|Stage IV Small Lymphocytic Lymphoma|Testicular Lymphoma|Waldenstrom Macroglobulinemia
Interventions: OTHER: Pharmacodynamic Studies|OTHER: Fatigue Inventory|OTHER: Pharmacogenomic studies|DRUG: AR-42
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Tele-physical Therapy in Patients With Type 2 Diabetes Mellitus Following COVID-19 Infection.
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|COVID-19
Interventions: OTHER: Tele physical therapy|OTHER: Patient educationa and Conventional exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Trial On The Utility and Impact Of Computed Tomography and Serum CA-125 In the Management of Newly Diagnosed Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: OTHER: CA 125 and CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Omega3 Wound Fish Skin Graft in the Treatment of DFUs
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: Kerecis Omega3 Wound|DEVICE: Fibracol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conventional Endoscopic Techniques Versus EndoRotor® System for Necrosectomy of Walled of Necrosis
Status: RECRUITING
Conditions: Acute Pancreatitis|Necrosis; Pancreas, Acute (Infectious)
Interventions: DEVICE: EndoRotor® System (Interscope, Inc., Northbridge, MA USA),|PROCEDURE: Conventional endoscopic devices (according to standards of care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Ureteral Length Using Computed Tomography (CT)
Status: COMPLETED
Conditions: Ureteral Calculi|Hydronephrosis|Ureteral Obstruction
Interventions: DEVICE: Ureteral catheterization - Cook Urological Inc. open end ureteral catheter 5FR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Predictive algoRithm for EValuation and Intervention in SEpsis
Status: COMPLETED
Conditions: Sepsis|Septic Shock|Severe Sepsis
Interventions: OTHER: Severe Sepsis Prediction|OTHER: Severe Sepsis Detection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 68Ga-citrate PET/CT for the Diagnosis of Chronic Prosthetic Hip or Knee Infection
Status: RECRUITING
Conditions: Prosthetic Joint Infection
Interventions: DIAGNOSTIC_TEST: 68Ga-citrate PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Study of Allogeneic Adipovarian Active Protein in the Treatment of Severe Idiopathic Pulmonary Fibrosis
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Cell Free Fat Extract(CEFFE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Therapeutic Touch and Mother's Voice on Pain and Comfort Level During Nasal CPAP Application
Status: COMPLETED
Conditions: Preterm Infants|Nasal Continuous Positive Airway Pressure|Pain Management
Interventions: OTHER: Mother's Voice|OTHER: Therapeutic Touch|OTHER: Mother's Voice +Therapeutic Touch|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Of Pregabalin (Lyrica) In Patients With Painful Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathy, Painful
Interventions: DRUG: pregabalin (Lyrica)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Rehabilitation for Patients Receiving Radiation Therapy for Thoracic Cancers
Status: TERMINATED
Conditions: Lung Cancer|Esophageal Cancer|Thoracic Cancer|Hodgkin Lymphoma|Hodgkin Disease|Non-hodgkin Lymphoma|Sarcoma|Thymoma|Breast Cancer
Interventions: PROCEDURE: Home-based cardiac rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Popliteal Artery of Treatment With Balloon Angioplasty vs. SUPERA VERITAS Peripheral Stent System
Status: WITHDRAWN
Conditions: Peripheral Vascular Disease
Interventions: DEVICE: IDEV SUPERA Stent|DEVICE: Percutaneous Transluminal Angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease
Status: NOT_YET_RECRUITING
Conditions: Moderately to Severely Active Crohn Disease
Interventions: DRUG: Obefazimod|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Two Treatment Modules in Chinese Subjects With Moderate to Severe Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: Adalimumab|BIOLOGICAL: Placebo for adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RCT of Efficacy of Amoxicillin Over Ampicillin on Severe Pneumonia
Status: COMPLETED
Conditions: Treatment Failure|Lethargy|Altered Mental Status|Convulsion, Non-Epileptic|Hypoxia|Feeding; Difficult, Newborn
Interventions: DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Buckle Me Up!: A Digital Emergency Department Discharge Intervention for Child Car Safety
Status: COMPLETED
Conditions: Safety Issues|Injuries|Car Accident
Interventions: BEHAVIORAL: CIAS (Computer Intervention Authoring Software)|BEHAVIORAL: Standard Printed Discharge Instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Ease of Use and Correct Use Study of Placebo ELLIPTA® Inhaler in COPD Subjects
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Placebo|OTHER: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase II Trial of Adjuvant Cisplatin and Radiation With Pembrolizumab in Resected Head and Neck Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer
Interventions: DRUG: Pembrolizumab|PROCEDURE: Surgery|RADIATION: Radiation Therapy|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptance and Commitment Therapy (ACT) in Groups for Obsessive Compulsive Disorder: A Clinical Trial in Brazil
Status: ACTIVE_NOT_RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: OTHER: Group acceptance and commitment therapy (ACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SU-101 Compared With Procarbazine in Treating Patients With Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: leflunomide|DRUG: procarbazine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Epidural Electrical Stimulation to Restore Hemodynamic Stability and Trunk Control in People With Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DEVICE: ARC-IM Investigational System implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Fundamental Aspects of Prosthetics and Translocation of Mitral Valve Chordae
Status: ACTIVE_NOT_RECRUITING
Conditions: Degenerative Mitral Valve Disease
Interventions: PROCEDURE: Mitral valve chordae prosthesis|PROCEDURE: Mitral valve chordae translocation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Templates as Cognitive Aids in Emergency Airway Equipment Preparation: the Template Airway Trial
Status: RECRUITING
Conditions: Airway Management
Interventions: OTHER: Endotracheal Intubation|OTHER: Supraglottic Airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation in Older Persons With Knee Pain (Knee Pain and tDCS): Randomized Pilot Study
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exercise by Mechanical Hippotherapy Device on Postural Stability and Balance in Stroke
Status: COMPLETED
Conditions: Stroke|Gait, Hemiplegic|Balance, Postural
Interventions: OTHER: exercise by hippotherapy device|OTHER: conventional rehabilitation|OTHER: postural control exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: T1 Squamous Cell Carcinomas of the Lip
Status: ACTIVE_NOT_RECRUITING
Conditions: Lip|Lip Cancer|Lip SCC|Squamous Cell Carcinoma|Squamous Cell Carcinoma of the Lip|Surgery|Surgical Margin|Recurrence|Metastasis|Tumor Free Margins
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunization of Children Previously Primed With GSK Pneumococcal Vaccine GSK1024850A and of Unprimed Children in Nigeria
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Pneumococcal vaccine GSK1024850A|BIOLOGICAL: InfanrixTM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Narcotic Versus Non-narcotic Medication for Pain Management After Wrist/Hand Fractures
Status: UNKNOWN
Conditions: Distal Radius Fracture|Pain Management|Metacarpal Fracture
Interventions: DRUG: Hydrocodone 5Mg/Acetaminophen 500Mg Tab|DRUG: Acetaminophen 500Mg Tab|DRUG: Ibuprofen 600 mg tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Postoperative Compex Rehab NMES Use for Total Knee Arthroplasty Patients
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Compex Rehab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Pharmacokinetic and Efficacy Study of a 10% Triple Virally Reduced Intravenous Immune Globulin Solution in Patients With Primary Immunodeficiency (Hypo- or Agammaglobulinemia)
Status: COMPLETED
Conditions: Primary Immunodeficiency Diseases (PID)|Agammaglobulinemia|Hypogammaglobulinemia
Interventions: DRUG: Immune Globulin Intravenous (Human), 10% TVR (Triple Virally Reduced) Solution|DRUG: Gammagard S/D (Solvent/Detergent)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioural Therapy With Checklist for Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: BEHAVIORAL: behavioural therapy with written checklist form to complete|DRUG: Antimuscarinic drugs used in overactive bladder|BEHAVIORAL: behavioural therapy with written guideline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gold Sodium Thiomalate in Treating Patients With Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: gold sodium thiomalate|GENETIC: gene expression analysis|OTHER: fluorine F 18 fluorothymidine|OTHER: mass spectrometry|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: ExAblate Blood-Brain Barrier Disruption for Glioblastoma in Patients Undergoing Standard Chemotherapy
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DEVICE: BBB Disruption with Chemotherapy Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Balneotherapy and Peloid Therapy Impact Small Joint Diseases
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis|Hand Osteoarthritis|Foot Osteoarthritis
Interventions: OTHER: Regular rehababilitation|OTHER: Heat procedures|OTHER: Healing mud application|OTHER: Mineral water bath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Extension Study Of Tanezumab When Administered By Subcutaneous Injection To Patients With Osteoarthritis
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: BIOLOGICAL: Tanezumab|BIOLOGICAL: Tanezumab|BIOLOGICAL: Tanezumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Trial of Stannsoporfin in Neonates With Hyperbilirubinemia
Status: TERMINATED
Conditions: Hyperbilirubinemia, Neonatal
Interventions: DRUG: Stannsoporfin|OTHER: Placebo|OTHER: PhotoTherapy (as needed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of VF001-DP in Patients With Chronic Venous Leg Ulcers
Status: UNKNOWN
Conditions: Ulcer|Leg Ulcer|Varicose Ulcer|Pathologic Processes|Skin Ulcer|Skin Diseases|Vascular Diseases|Cardiovascular Diseases
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: VF001-DP LD|BIOLOGICAL: VF001-DP HD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of 2 Dietary Supplement Beverages Designed to Maintain Healthy Blood Pressure.
Status: NOT_YET_RECRUITING
Conditions: Safety Issues|Tolerance
Interventions: DIETARY_SUPPLEMENT: Treatment 1|DIETARY_SUPPLEMENT: Treatment 2|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Biological Therapies Following Peripheral Stem Cell Transplantation in Treating Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, or Advanced Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Lymphoma
Interventions: DRUG: aldesleukin|DRUG: filgrastim|DRUG: recombinant human stem cell factor|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ZYD1, Following Subcutaneous Administration in Healthy Volunteers
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ZYD1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proton Pump Inhibitor Preventing Upper Gastrointestinal Injury In Patients On Dual Antiplatelet Therapy After CABG
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastrointestinal Ulcer (Peptic) or Erosion|Anti-Platelet Therapy|Coronary Artery Bypass
Interventions: DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Glutamine and Traumatic Brain Injury
Status: NOT_YET_RECRUITING
Conditions: Brain Injuries, Traumatic
Interventions: DRUG: Glutamine|OTHER: Placcebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Saxagliptin Co-administered With Dapagliflozin in Combination With Metformin Compared to Sitagliptin in Combination With Metformin in Adult Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Therapy Alone
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Saxagliptin|DRUG: Dapagliflozin|DRUG: Sitagliptin|DRUG: Placebo matching with Saxagliptin|DRUG: Placebo matching with Dapagliflozin|DRUG: Placebo matching with Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Fish Oil Supplementation on Endothelial Function, Heart Rate Variability and Intimal Media Thickness of Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Omacor (omega-3-acid ethyl esters)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Photosensitivity in Dabrafenib or Vemurafenib Treated Metastatic Melanoma Patients - a Phase IIa/IIb Study
Status: TERMINATED
Conditions: Metastatic Melanoma (Carrying BRAF V600 Mutation)
Interventions: DRUG: Dabrafenib|DRUG: Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label, International, Multi-centre, Phase I/IIa Study of Lenalidomide (Revlimid) and Romidepsin (Istodax) for Relapsed /Refractory Hodgkin Lymphoma, Mature T-cell Lymphoma and Multiple Myeloma. (RId Study)
Status: TERMINATED
Conditions: Hodgkin's Lymphoma|Mature T-cell Lymphoma|Multiple Myeloma
Interventions: DRUG: lenalidomide (Revlimid) and romidepsin (Istodax)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction (DDI) Study for TD-9855
Status: COMPLETED
Conditions: Drug Drug Interaction (DDI)
Interventions: DRUG: TD-9855|DRUG: Fluvoxamine|DRUG: Itraconazole|DRUG: Caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Hyaluronic Acid on Perimplantitis
Status: COMPLETED
Conditions: Peri-Implantitis
Interventions: DRUG: Hyaluronic Acid|DRUG: Hydroxypropyl Guar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of TAS-118 Plus Oxaliplatin Versus S-1 Plus Cisplatin in Patients With Advanced Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: TAS-118 plus Oxaliplatin|DRUG: S-1 plus Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Brushing With Salvadorapersica (Miswak) Sticks on Salivary Streptococcus Mutants and Plaque Level in Children: A Clinical Trial
Status: COMPLETED
Conditions: Plaque, Dental
Interventions: COMBINATION_PRODUCT: brushing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of NCCL Asociated With Gingival Recession With B.O.P.T. Technique
Status: ACTIVE_NOT_RECRUITING
Conditions: Abfraction
Interventions: PROCEDURE: Treatment of the abfraction with BOPT technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of CDB-2914 Versus Placebo in the Prevention of Follicular Rupture Post-luteinizing Hormone (LH) Surge
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: CDB-2914 (ulipristal acetate)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose:
Clinical trial: The Effect of Noise Pollution on Lung Sound Recognition by Medical Students
Status: COMPLETED
Conditions: Lung Sound
Interventions: OTHER: Exposed group (EXP) - 35 students. EXP group will learn pathological and nonpathological sounds for 3 days.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SGLT2-Inhibitors for Sleep Apnea in Heart Failure
Status: WITHDRAWN
Conditions: Heart Failure|Sleep Disordered Breathing
Interventions: DRUG: Dapagliflozin|DEVICE: WatchPat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 3 Evaluation of Re-Injection of NX-1207 for the Treatment of Benign Prostatic Hyperplasia (BPH)(NX02-0022)
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia|BPH|Lower Urinary Tract Symptoms (LUTS)|LUTS
Interventions: DRUG: NX-1207
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Decitabine and Temozolomide in the Treatment of Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DRUG: Decitabine|DRUG: Temozolomide|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Trial of Duloxetine in Outpatients With Irritable Bowel Syndrome Symptoms and Co-Morbid Major Depression
Status: COMPLETED
Conditions: Major Depression|Irritable Bowel Syndrome
Interventions: DRUG: Duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Physiologic and Standard Sex Steroid Replacement Regimens in Women With Premature Ovarian Failure
Status: COMPLETED
Conditions: Premature Ovarian Failure
Interventions: DRUG: Ethinylestradiol / Norethisterone|DRUG: Estradiol / Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Long-Term Efficacy and Safety of LIB003 in CVD or High Risk for CVD Patients Needing Further LDL-C Reduction
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Risk Factor|Cardiovascular Diseases|Cardiovascular Stroke|Hypercholesterolemia
Interventions: DRUG: lerodalcibep|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Phenazopyridine for Pain Following Urodynamics
Status: NOT_YET_RECRUITING
Conditions: Pain After Urodynamic Testing
Interventions: DRUG: Phenazopyridine Hydrochloride 99.5 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study To Evaluate Whether Food Affects The Plasma Drug Levels Of A 35 mg Single Dose Of PF-04447943 Taken Orally In Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-04447943|DRUG: PF-04447943
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Study of the Effects of Probiotics Upon Infectious Episodes in Subject Aged More Than 60, During Winter.
Status: COMPLETED
Conditions: Infectious Episodes (ENT, Gastro-intestinal and Pulmonary)
Interventions: DIETARY_SUPPLEMENT: Lactobacillus helveticus R0052, Bifidobacterium bifidum R0071, Bifidobacterium infantis R0033|DIETARY_SUPPLEMENT: Starch of potato
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Investigation of the Effects of Family-Focused Therapy in the Early Period of Bipolar Disorder and Psychotic Disorder
Status: COMPLETED
Conditions: Mental Disorder in Adolescence|Bipolar Disorder|Psychosis|Family Relations
Interventions: BEHAVIORAL: Family-Focused Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Bivalirudin Versus Heparin in Neonatal and Pediatric ECMO
Status: COMPLETED
Conditions: Extracorporeal Membrane Oxygenation Complication|Pediatric ALL|Anticoagulants
Interventions: DRUG: Bivalirudin|DRUG: Unfractionated heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Engaging Church Health Ministries to Decrease Coronavirus Disease-19 Vaccine Hesitancy in Underserved Populations
Status: WITHDRAWN
Conditions: COVID-19
Interventions: BEHAVIORAL: Active Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: One-Month DAPT in CABG Patients
Status: NOT_YET_RECRUITING
Conditions: Chronic Coronary Disease
Interventions: DRUG: Ticagrelor 90 MG|DRUG: Ticagrelor placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cardiovascular Effects in Psoriasis Patients Treated With Adalimumab.
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Adalimumab 40 MG/0.8 ML Subcutaneous Solution [HUMIRA]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Emetine for Viral Outbreaks (EVOLVE)
Status: RECRUITING
Conditions: COVID-19
Interventions: DRUG: Emetine Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention Protocol for Automated Point-of-Care Surveillance of Outpatient Delays in Cancer Diagnosis
Status: WITHDRAWN
Conditions: Lung Cancer|Bladder Cancer|Colorectal Cancer|Hepatocellular Carcinoma|Breast Cancer
Interventions: BEHAVIORAL: Communication of Patients Lost to Follow-up to Providers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of TU-100 in Patients Undergoing Laparoscopic Colectomy
Status: COMPLETED
Conditions: Postoperative Ileus
Interventions: DRUG: Daikenchuto (TU-100)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Marginal Bone Loss Using Computer Guided Ridge Splitting Technique With Simultaneous Implant Placement.
Status: UNKNOWN
Conditions: Marginal Bone Loss|Computer Guided|Ridge Splitting
Interventions: DEVICE: Computer guided alveolar ridge splitting technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerance and Initial Efficacy of EGFRvIII CAR-T on Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: Recurrent Glioblastoma
Interventions: DRUG: Targeted Epidermal Growth Factor Receptor Variant III(EGFRvIII) autochimeric antigen receptor T cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Adding High Power Pain Threshold Ultrasound to Traditional Therapy on Axioappendicular Muscles Amplitude and Fatigue in Mechanical Neck Pain Randomized Clinical Trials
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: high power pain threshold ultrasound|OTHER: traditional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Dose Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HM15912 in Healthy Korean Subjects
Status: COMPLETED
Conditions: Pharmacology
Interventions: DRUG: HM15912|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LDL Receptor Under Ezetimibe and Simvastatin
Status: COMPLETED
Conditions: Healthy Men
Interventions: DRUG: ezetimibe|DRUG: simvastatin|DRUG: ezetimibe plus simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Oxygen Therapy on 6MWD in PAH and CTEPH Patients With Hypoxemia
Status: COMPLETED
Conditions: Oxygen Deficiency|Pulmonary Arterial Hypertension|CTEPH
Interventions: DRUG: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Naproxen for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Osteoarthritis, Hip
Interventions: DRUG: Fasinumab|DRUG: Naproxen|DRUG: Fasinumab-matching placebo|DRUG: Naproxen-matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT