pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intraoperative Ultrasound in Patients Undergoing Transsphenoidal Surgery for Pituitary Adenoma
Status: COMPLETED
Conditions: Pituitary Adenoma
Interventions: DEVICE: Intraoperative ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Indocyanine Green Tracer Using in Laparoscopic Distal Gastrectomy for Early Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Early Gastric Cancer|Indocyanine Green|Lymph Node Dissection
Interventions: DRUG: Indocyanine Green
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Immunotherapy for Peanut Allergy (PMIT)
Status: COMPLETED
Conditions: Food Hypersensitivity
Interventions: BIOLOGICAL: Peanut OIT|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ubiquinone vs. Ubiquinol Supplementation
Status: NOT_YET_RECRUITING
Conditions: IVF
Interventions: DRUG: Ubiquinone 200 Mg Oral Capsule|DRUG: Ubiquinol 100 MG Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Decision Aid to Facilitate Shared Decision Making During Treatment in Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Visual Decision Aid and Shared Decision Making Model|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biosimilar Erythropoietin in Anaemia Treatment (Correction Phase Study)
Status: TERMINATED
Conditions: Renal Anaemia
Interventions: DRUG: EPIAO®|DRUG: EPREX®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-finding Study of LFB-R593, A Monoclonal Anti-RhD Antibody, in Healthy RhD Negative Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: polyclonal anti-D immunoglobulin|DRUG: monoclonal anti-D immunoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Protecting Native Families From COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: COVID-19 Symptom Monitoring System|BEHAVIORAL: Motivational Interviewing and COVID-19 Symptom Monitoring System|OTHER: Supportive Services
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Building a Behavioural Intervention Programme to Improve Self-Management of Diabetes
Status: UNKNOWN
Conditions: Diabetes
Interventions: BEHAVIORAL: Fast-forwarding in Cycle 1|BEHAVIORAL: Goal-Setting plus Weekly Nudge in Cycle 1|BEHAVIORAL: Fast-forwarding in Cycle 2|BEHAVIORAL: Goal-Setting plus Weekly Nudge in Cycle 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Blunt Fascial vs. Veress Needle Peritoneal Entry in Laparoscopic Gynecologic Surgery
Status: RECRUITING
Conditions: Laparoscopic Surgery
Interventions: PROCEDURE: Blunt fascial abdominal entry|PROCEDURE: Veress needle abdominal entry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Purpose of Study is to Evaluate the Safety, Pharmacokinetics and Anti-tumor Effects of CKD-702 in Patients With Advanced or Metastatic Non-small Cell Lung Cancer Who Failed to Standard Therapy
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: CKD-702
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Home Care Device for High-Risk Diabetic Patients
Status: UNKNOWN
Conditions: Diabetes|Neuropathic Limb|Elevated Temperature|Shear Pressure|Increased Temperatures
Interventions: DEVICE: TempTouchRM|DEVICE: Offloading
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of a Respiratory Muscle Warm-up Prior to Exercise in Patients With Chronic Obstructive Pulmonary Disease
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Inspiratory Warm Up|OTHER: Expiratory Warm Up|OTHER: Combination Warm Up|OTHER: Control Trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose:
Clinical trial: Augmented Infant Resuscitator (AIR): Transitioning a Novel Behavior Change Innovation to Drive Newborn Ventilation Skills Enhancement
Status: ACTIVE_NOT_RECRUITING
Conditions: Asphyxia Neonatorum|Birth Asphyxia|Perinatal Asphyxia
Interventions: DEVICE: Augmented Infant Resuscitator (AIR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Evaluate the Efficacy and Safety of Toripalimab in Combination With Axitinib Versus Sunitinib Monotherapy in Advanced Renal Cell Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Disease: Unresectable or Metastatic Renal Cell Carcinoma Focus of the Study:PFS Assessed by IRC Per RECIST 1.1
Interventions: COMBINATION_PRODUCT: Biological : Toripalimab Drug: Axitinib|DRUG: sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic, Pharmacokinetic, and Tolerability Study of a Liquid Form of Lubiprostone in Adult Subjects With Chronic Idiopathic Constipation
Status: COMPLETED
Conditions: Chronic Idiopathic Constipation
Interventions: DRUG: Lubiprostone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CIRCULATING MICRO-RNA (miRNA) AND AR-V7 MUTATIONAL STATUS IN METASTATIC CASTRATION-RESISTANT PROSTATE CANCER (CRPC): PRIMERA+ STUDY (PROSTATE CANCER INNOVATING MARKERS OF EXPECTED RESPONSE TO AGONIST LHRH+ ANDROGEN RECEPTOR INHIBITION
Status: UNKNOWN
Conditions: D011471|D064129|D035683|D009360|D014408
Interventions: DIAGNOSTIC_TEST: Periodic ARV7 and miRNA evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of a Recombinant Human Plasminogen Activator to Treat Acute Ischemic Stroke.
Status: COMPLETED
Conditions: Cerebrovascular Accident
Interventions: GENETIC: Recombinant Human Plasminogen Activator (HTUPA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AB801 Monotherapy and Combination Therapy in Participants With Advanced Malignancies
Status: RECRUITING
Conditions: Advanced Cancer
Interventions: DRUG: AB801|DRUG: Zimberelimab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: OLT1177 Gel|OTHER: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetic Retinopathy Sulodexide Study
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DRUG: sulodexide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis
Status: RECRUITING
Conditions: Colitis, Ulcerative
Interventions: DRUG: Ozanimod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Outcomes of Laparoscopic Repair of Paravaginal Defects
Status: COMPLETED
Conditions: Prolapse, Vaginal|Paravaginal Cystocele
Interventions: PROCEDURE: laparoscopic paravaginal repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SPD489 Adult Major Depressive Disorder (MDD) Open-label Safety and Tolerability Rollover Extension Study
Status: TERMINATED
Conditions: Major Depressive Disorder
Interventions: DRUG: SPD489 (Lisdexamfetamine dimesylate) + Antidepressant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myocardial Infarction Genes (MI-GENES) Study
Status: COMPLETED
Conditions: Coronary Artery Disease|Myocardial Infarction|Genomic Risk Communication
Interventions: OTHER: Genetic Risk Score
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pitolisant Effects on Affect and Cognition Exploratory Study (PEACE Study)
Status: COMPLETED
Conditions: Anhedonia|Cognitive Function
Interventions: DRUG: Pitolisant 17.8 MG [Wakix]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Improving the Safety of Oral Immunotherapy for Cow's Milk Allergy
Status: COMPLETED
Conditions: Food Allergy
Interventions: OTHER: SLIT to cow's milk|OTHER: Low dose OIT|OTHER: Conventional OIT to cow's milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Migration and Survival of All-polyethylene Tibial All Poly Components Compared to the Metal-backed Modular Components of the Triathlon CS Total Knee System. A Single Center RSA Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Arthritis
Interventions: DEVICE: Triathlon CS Knee System with all-polyethylene tibial components|DEVICE: Triathlon CS Knee System with metal-backed modular components
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Self-directed and Supervised Pulmonary Rehabilitation Approach on Cough and Sputum.
Status: COMPLETED
Conditions: COPD|Pulmonary Disease
Interventions: OTHER: Physiotherapy Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GPED Regimen for Relapsed/Refractory or Advanced ENKTCL
Status: UNKNOWN
Conditions: Extranodal NK/T-cell Lymphoma, Nasal Type
Interventions: DRUG: gemcitabin|DRUG: Pegaspargase|DRUG: Etoposide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endosonography-guided Gallbladder Drainage vs Non-endoscopic Treatment in Inoperable Acute Cholecystitis
Status: RECRUITING
Conditions: Cholecystitis, Acute
Interventions: PROCEDURE: Endoscopic treatment group (EUS-GBD group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research Study to Compare Semaglutide Tablets With Empagliflozin or Metformin Tablets in People With Type 2 Diabetes
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Semaglutide|DRUG: Empagliflozin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of BHT-3021 in Subjects With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes|Hypoglycemia
Interventions: DRUG: BHT-3021|DRUG: BHT-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bright Light Intervention to Reduce Students' Stress
Status: RECRUITING
Conditions: Psychological Stress|Physiological Stress|Sleep Disorders, Circadian Rhythm
Interventions: OTHER: Bright light intervention|OTHER: Reddish placebo light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica (KOMFORT)
Status: COMPLETED
Conditions: Pruritus|Notalgia Paresthetica
Interventions: DRUG: difelikefalin 2.0 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Vaccine (CDX-1401) With or Without a Biologic Drug (CDX-301) for the Treatment of Patients With Stage IIB-IV Melanoma
Status: COMPLETED
Conditions: Cutaneous Melanoma|Melanoma|Melanoma of Unknown Primary|Mucosal Melanoma|Ocular Melanoma|Stage IIB Cutaneous Melanoma AJCC v6 and v7|Stage IIC Cutaneous Melanoma AJCC v6 and v7|Stage III Cutaneous Melanoma AJCC v7|Stage IIIA Cutaneous Melanoma AJCC v7|Stage IIIB Cutaneous Melanoma AJCC v7|Stage IIIC Cutaneous Melanoma AJCC v7|Stage IV Cutaneous Melanoma AJCC v6 and v7
Interventions: BIOLOGICAL: DEC-205/NY-ESO-1 Fusion Protein CDX-1401|DRUG: Poly ICLC|BIOLOGICAL: Recombinant Flt3 Ligand
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Occupation-based Sleep Program for People With Insomnia
Status: COMPLETED
Conditions: Insomnia, Primary|Insomnia
Interventions: BEHAVIORAL: Occupation-based sleep intervention program|BEHAVIORAL: Insomnia Education Program at Integrated Mental Health Clinic (IMHC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strength Training Study for Survivors of Breast and Gynecologic Cancer
Status: COMPLETED
Conditions: Breast Cancer|Gynecologic Cancer|Ovarian Cancer|Uterine Cancer|Cervical Cancer
Interventions: BEHAVIORAL: Strength Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study for the Treatment of Diabetic Peripheral Neuropathic Pain
Status: COMPLETED
Conditions: Diabetic Neuropathies
Interventions: DRUG: Duloxetine hydrochloride - 40 mg|DRUG: placebo|DRUG: Duloxetine hydrochloride - 60 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies
Status: RECRUITING
Conditions: Hematologic Neoplasms
Interventions: DRUG: Mycophenolate Mofetil|PROCEDURE: Allogeneic HSCT|DRUG: Fludarabine|DRUG: Sirolimus|DRUG: Filgrastim|DRUG: Cyclophosphamide|DRUG: Mesna|PROCEDURE: Total Body Irradiation (TBI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Thyroid Cartilage Plane Block for Awake Intubation
Status: RECRUITING
Conditions: Superior Laryngeal Nerve Block
Interventions: BEHAVIORAL: Ultrasound-guided bilateral Thyroid Cartilage Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock
Status: RECRUITING
Conditions: Septic Shock|Sepsis|Pathologic Processes|Shock|Systemic Inflammatory Response Syndrome|Inflammation|Infections
Interventions: BIOLOGICAL: Allogeneic umbilical cord-derived human mesenchymal stromal cells|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sirolimus- and Paclitaxel-Eluting Stents for Small Vessels (ISAR-SMART-3)
Status: COMPLETED
Conditions: Coronary Disease
Interventions: DEVICE: Sirolimus-eluting stent (Cypher)|DEVICE: Paclitaxel-eluting stent (Taxus)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of L-arginine on Microcirculation, Myogenesis and Angiogenesis Associated With Aging, Sarcopenia and Diabetes
Status: COMPLETED
Conditions: Aging|Sarcopenia|Type 2 Diabetes|Microcirculation
Interventions: DIETARY_SUPPLEMENT: L-arginine|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexmedetomidine on Emergence Agitation and Postoperative Behavior Changes in Children
Status: UNKNOWN
Conditions: Emergence Agitation
Interventions: DRUG: Dexmedetomidine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Inhaled and Intravenous Milrinone in Patients With Severe Pulmonary Hypertension
Status: RECRUITING
Conditions: Pulmonary Hypertension Due to Left Heart Disease
Interventions: DRUG: Milrinone inhalation|DRUG: Milrinone infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Brief Mindfulness Intervention for Pain Before an In-clinic Orthopedic Procedure
Status: RECRUITING
Conditions: Pain|Chronic Pain|Acute Pain
Interventions: BEHAVIORAL: Mindful Pain Management|BEHAVIORAL: Pain Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gallium-68 PSMA-11 PET Imaging in Prostate Cancer Patients
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Ga-68 labeled PSMA-11|DEVICE: Positron emission tomography-computed tomography (PET/CT)|DEVICE: Positron emission tomography-magnetic resonance imaging (PET/MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Extended-release Tablets in Pediatric Subjects Aged 5 to 17 Years With Active, Mild to Moderate Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Low Dose Budesonide|DRUG: High Dose Budesonide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Usability Evaluation of Menai CPAP Masks
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Menai mask (full face)|DEVICE: Menai Standard mask (full face)|DEVICE: Menai mask (nasal)|DEVICE: Menai Standard mask (nasal)|DEVICE: Menai mask (pillows)|DEVICE: Menai Standard mask (pillows)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Stimulating Catheter for Lumbar Plexus
Status: COMPLETED
Conditions: Knee Arthritis Disease
Interventions: DEVICE: stimulong 100, pajunk, germany|DEVICE: plexolong 100, pajunk, germany
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy
Status: COMPLETED
Conditions: Schizophrenia|Impaired Cognition
Interventions: DRUG: EVP-6124|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rhomboid Intercostal and Subserratus Plane (RISS) Block on Postoperative Painafter Open Nephrectomy Surgery
Status: UNKNOWN
Conditions: Rhomboid Intercostal Block
Interventions: DRUG: Rhomboid Intercostal and Sub-Serratus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial Comparing Sequential Addition of Insulin Aspart Versus Further Dose Increase With Insulin Degludec/Liraglutide in Subjects With Type 2 Diabetes Mellitus, Previously Treated With Insulin Degludec/Liraglutide and Metformin and in Need of Further Intensification
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/liraglutide|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Time-efficient Inspiratory Muscle Strength Training for Lowering Systolic Blood Pressure
Status: RECRUITING
Conditions: Blood Pressure|Endothelial Dysfunction|Hypertension
Interventions: OTHER: Inspiratory muscle strength training|OTHER: Brisk walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Pharmacokinetics of MFGR1877S in Patients With Relapsed or Refractory t(4;14)-Positive Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: MFGR1877S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pegylated Interferon α-2b in Combination With Ruxolitinib for Treating Hydroxyurea-resistant/Intolerant PV
Status: RECRUITING
Conditions: Polycythemia Vera
Interventions: DRUG: Ruxolitinib|DRUG: Pegylated interferon α-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fibrosis Lessens After Metabolic Surgery
Status: RECRUITING
Conditions: Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD)|Non-Alcoholic Fatty Liver Disease|Metabolic Dysfunction-Associated Steatohepatitis (MASH)|Liver Fibrosis|Obesity
Interventions: PROCEDURE: Metabolic surgery|DRUG: Incretin-Based Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Of Paricalcitol and Cholecalciferol(Vitamin D3) in the Treatment Of Secondary Hyperparathyroidism in Patients After ROUX-EN-Y Gastric Bypass Surgery
Status: COMPLETED
Conditions: Gastric Bypass|Parathyroid Hormone
Interventions: DRUG: Paricalcitol|DRUG: Cholecalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study With Clinical Endpoints to Evaluate the Safety and Therapeutic Equivalence of Permethrin Cream 5% & Elimite™ in Subjects With Scabies
Status: COMPLETED
Conditions: Scabies
Interventions: DRUG: Permethrin Cream 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SugarFACT - Sugar Requirements For African Children Trial
Status: TERMINATED
Conditions: Hypoglycemia Non Diabetics|Emergencies|Pediatric ALL|Critical Illness
Interventions: DRUG: 10% dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound - Guided Paramedian Techniques in Spinal Anesthesia
Status: COMPLETED
Conditions: Anaesthesia
Interventions: PROCEDURE: pre-procedure ultrasound guided paramedian spinal|PROCEDURE: Conventional landmark guided midline spinal anaesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Super-Rehab: a Novel Approach to Reverse Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation|Overweight and Obesity
Interventions: BEHAVIORAL: Super Rehab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fructooligosaccharides in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant
Status: COMPLETED
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Recurrent Hematologic Malignancy
Interventions: OTHER: Fructooligosaccharide|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Preliminary Efficacy of the Treatment of Kidney Allografts With Curcumin-containing Preservation Solution
Status: UNKNOWN
Conditions: End Stage Renal Failure With Renal Transplant
Interventions: DEVICE: CDC solution|DEVICE: UW-solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: RCT on 3 Types of Hysterectomy
Status: RECRUITING
Conditions: Minimally Invasive Surgery
Interventions: PROCEDURE: vNOTES vs Vaginal Hysterectomy|PROCEDURE: vNOTES vs Laparoscopic Hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensiva 2.0: Improve the Communication Towards Families of Critically Ill Patients
Status: UNKNOWN
Conditions: Critical Illness|Stress Disorders, Traumatic, Acute|Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Enhanced communication by brochure, website and posters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial of Postoperative Whole Brain Radiation Therapy vs. Salvage Stereotactic Radiosurgery Therapy for Metastasis
Status: COMPLETED
Conditions: Brain Neoplasms|Neoplasm Metastasis
Interventions: DEVICE: Whole brain radiation therapy arm|DEVICE: Salvage stereotactic radiosurgery arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transplacental Aspirin Therapy for Early Onset Fetal Growth Restriction
Status: WITHDRAWN
Conditions: Fetal Growth Restriction|Fetal Growth Retardation|Intrauterine Growth Restriction|Intrauterine Growth Retardation
Interventions: DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Toripalimab Combined With Docetaxel or Nab-paclitaxel in Patients With Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer Stage IV
Interventions: DRUG: Toripalimab|DRUG: Docetaxel|DRUG: nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Instrumental Sealing of Arterial Puncture Site Closure Device Versus Manual Compression Trial
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: FemoSeal®|DEVICE: ExoSeal®|OTHER: Manual compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ICON-2: FMT and Bezlotoxumab Compared to FMT and Placebo for Patients With IBD and CDI
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammatory Bowel Diseases|Clostridium Difficile Infection
Interventions: DRUG: Bezlotoxumab|DRUG: Placebo|DRUG: Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Two Formulation of Pregabalin
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy|Fibromyalgia|Partial Seizure Disorder
Interventions: DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serelaxin To Lower Portal Pressure
Status: COMPLETED
Conditions: Liver Cirrhosis|Hypertension, Portal
Interventions: DRUG: Serelaxin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Zingiber Officinalis on Nausea and Vomiting in Patients Receiving Cisplatin Based Regimens
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: DIETARY_SUPPLEMENT: Ginger|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Milnacipran on Sleep Disturbance in Fibromyalgia
Status: COMPLETED
Conditions: Sleep Disorders|Fibromyalgia|Sleep
Interventions: DRUG: Milnacipran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving the Quality of Private Sector Health Care in West Bengal
Status: COMPLETED
Conditions: Myocardial Infarction|Diarrhea (Dysentery)|Asthma
Interventions: OTHER: Training|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Acetazolamide on Acute Mountain Sickness in Lowlanders Older Than 40 Years
Status: COMPLETED
Conditions: Acute Mountain Sickness
Interventions: DRUG: ACETAZOLAMIDE oral capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Safety and Preliminary Anti-tumor Activity of Debio 0123 as Monotherapy in Adult Participants With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: Debio 0123
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing (SIS.NET) to Standard Care in Patients Who Have Completed the Acute Phase of Treatment for Early Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: SIS.NET, Routine Follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rituximab and Galiximab in Treating Patients With Stage II, Stage III, or Stage IV Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: galiximab|BIOLOGICAL: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Mitochondrial-targeted Antioxidant on Mild Cognitive Impairment (MCI) Patients
Status: WITHDRAWN
Conditions: Alzheimer Disease, Early Onset|Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: MitoQ|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Semi-Factorial Cluster-Randomized Trial to Estimate the Effect Size of Community Mobilization and VCT Vans on the Adoption of Voluntary Counseling and Testing (VCT) Services in Andhra Pradesh, India: THE MCVCT STUDY
Status: WITHDRAWN
Conditions: HIV|AIDS|Epidemiology|Prevention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pembrolizumab With Combination Chemotherapy in Treating Participants With Locally Advanced or Metastatic Small Cell/Neuroendocrine Cancers of Urothelium or Prostate
Status: COMPLETED
Conditions: Bladder Small Cell Neuroendocrine Carcinoma|Castration-Resistant Prostate Carcinoma|Metastatic Bladder Urothelial Carcinoma|Metastatic Urethral Urothelial Carcinoma|Prostate Carcinoma Metastatic in the Bone|Prostate Neuroendocrine Neoplasm|Prostate Small Cell Carcinoma|Stage III Bladder Cancer AJCC v8|Stage III Prostate Cancer AJCC v8|Stage III Urethral Cancer AJCC v8|Stage IV Bladder Cancer AJCC v8|Stage IV Prostate Cancer AJCC v8|Stage IV Urethral Cancer AJCC v8|Stage IVA Bladder Cancer AJCC v8|Stage IVB Bladder Cancer AJCC v8|Ureter Small Cell Carcinoma|Urothelial Carcinoma
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Docetaxel|DRUG: Etoposide|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine Versus Propofol Effect on the Immune-mediatory Response for Abdominal Surgery
Status: UNKNOWN
Conditions: Major Abdominal Surgery
Interventions: DRUG: Ketamine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee
Status: RECRUITING
Conditions: Chondral Defect|Osteochondritis Dissecans (OCD)|Articular Cartilage Defect|Articular Cartilage Disorder of Knee
Interventions: BIOLOGICAL: MACI|PROCEDURE: microfracture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Vagus Nerve Stimulation as a Tool to Modulate Stomach-Brain Coupling in Depression
Status: ENROLLING_BY_INVITATION
Conditions: Depressive Disorder, Major
Interventions: DEVICE: Transcutaneous non-invasive vagus nerve stimulation (tVNS)|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Immunogenicity and Safety of Nonavalent Human Papillomavirus (HPV) Vaccine
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Papillomavirus Infection
Interventions: BIOLOGICAL: Nonavalent HPV study vaccine|BIOLOGICAL: GARDASIL® 9
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Does Visceral Manipulation Works in Treating Functional Dyspepsia?
Status: UNKNOWN
Conditions: Functional Dyspepsia
Interventions: PROCEDURE: Visceral Manipulation|DRUG: PPIs and/or Domperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Preemptive Therapy With CMV-specific T Cells Infusion to Prevent Refractory CMV Infection Post Transplantation
Status: COMPLETED
Conditions: CMV Infection
Interventions: BIOLOGICAL: Donor-derived CMVpp65-specific T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Slow Stroke Back Massage on Pain and Fatigue in Women With Fibromyalgia
Status: ENROLLING_BY_INVITATION
Conditions: Massage Intervention
Interventions: BEHAVIORAL: Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optical Tissue Identification for Myocardial Architecture
Status: ACTIVE_NOT_RECRUITING
Conditions: Ventricular Septal Defect|Complete Atrioventricular Canal|Tetralogy of Fallot With Pulmonary Stenosis
Interventions: DRUG: Fluorescite|DEVICE: Cellvizio 100 Series System with Confocal Miniprobes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Clinical Trial of Autologous CD7-CAR T Cells in the Treatment of High-risk Acute T-cell Leukemia / Lymphoma
Status: RECRUITING
Conditions: T Cell Lymphoma|T-cell Leukemia
Interventions: BIOLOGICAL: chimeric antigen receptor T cell treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lung UltrasouNd Guided Surfactant Therapy in Preterm Infants (LUNG Study)
Status: RECRUITING
Conditions: Respiratory Distress Syndrome, Newborn
Interventions: DIAGNOSTIC_TEST: Lung ultrasound score (LUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postconditioning in ST-elevation Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: PROCEDURE: Postconditioning|PROCEDURE: Control intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Olive Oil With Piroxicam Gel in Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Piroxicam|DIETARY_SUPPLEMENT: Olive Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Effects of Paricalcitol
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Paricalcitol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the 3-month Strut Coverage After Coronary Stenting by Optical Coherence Tomography; Cilotax and DESyne
Status: WITHDRAWN
Conditions: Patients in the Treatment of Subjects With All-comer Who Are to Undergo PCI
Interventions: DEVICE: Cilotax drug-eluting stents implantation|DEVICE: DESyne drug-eluting stents implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Unrestrictive Exercise Following Mid-Urethral Sling Surgery
Status: RECRUITING
Conditions: Stress Urinary Incontinence
Interventions: OTHER: No post-operative activity restrictions|OTHER: Standard post-operative activity restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bivalirudin in Elderly Patients With Acute ST-segment Elevation Myocardial Infarction
Status: UNKNOWN
Conditions: STEMI|Percutaneous Coronary Intervention|Aged
Interventions: DRUG: Bivalirudin|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Co-Axial Micro-Incision Versus Co-Axial Small Incision Cataract Surgery Using the Stellaris Enhancement System
Status: COMPLETED
Conditions: Cataract|Aphakia
Interventions: PROCEDURE: Coaxial Micro-Incision Cataract Surgery|PROCEDURE: Coaxial Small Incision Cataract Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oral Surgery in Patients Taking Direct Oral Anticoagulants
Status: COMPLETED
Conditions: Anticoagulants and Bleeding Disorders|Surgery|Postoperative Hemorrhage|Dentoalveolar Haemorrhage
Interventions: PROCEDURE: Oral surgical procedure followed by local hemostatic measures (insertion of gelatine sponge and wound suturing)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Efficacy/Safety of Symbicort® Turbuhaler®,Seretide™ Diskus™ 50/500 µg & Terbutaline Turbuhaler® 0.4 mg
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide/formoterol Turbuhaler|DRUG: Salmeterol/fluticasone Diskus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Control Study to Evaluate The Efficacy And Safety of Ozone-therapy in Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DEVICE: medical ozone therapy with humares|DRUG: conventional interferon-α
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tazemetostat for the Treatment of Moderate to Severe COVID-19 Infection
Status: WITHDRAWN
Conditions: COVID-19 Acute Respiratory Distress Syndrome|Cytokine Release Syndrome
Interventions: DRUG: Tazemetostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation Study of CART BP as a Wearable Cuffless Blood Pressure Monitor
Status: NOT_YET_RECRUITING
Conditions: Blood Pressure|Hypertension|Blood Pressure, High|Blood Pressure, Low|Hypotension
Interventions: DEVICE: CART BP|DEVICE: sphygmomanometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Electrical Stimulation to Accelerate Wound Healing
Status: COMPLETED
Conditions: Diabetes|Diabetic Foot Ulcer|Peripheral Neuropathy|Peripheral Arterial Disease
Interventions: DEVICE: Electrical Stimulation - Active|DEVICE: Electrical Stimulation - Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Efficacy and Safety of Benralizumab in Adult Patients With Mild to Moderate Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: Benralizumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Iressa as a First-Line Treatment in Chemonaive Patients With Inoperable Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Iressa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of Liposomal Cyclosporine A to Treat Bronchiolitis After Hematopoietic Transplant (BOSTON-4)
Status: TERMINATED
Conditions: Bronchiolitis Obliterans Syndrome (BOS)|GVHD, Chronic|Stem Cell Transplant Complications
Interventions: DRUG: Liposomal Cyclosporine A|DRUG: Liposomal Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Trial of Alprazolam 2 mg Tablets
Status: COMPLETED
Conditions: Anxiety Disorders
Interventions: DRUG: Alprazolam 2mg tablets|DRUG: Alprazolam 2 mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Investigate the Safety and Clinical Activity of Belantamab Mafodotin in Combination With Daratumumab, Lenalidomide and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Transplant Ineligible
Status: RECRUITING
Conditions: Multiple Myeloma|Neoplasms|Neoplasms, Plasma Cell|Gammopathy, Monoclonal|Paraproteinemias|Blood Protein Disorders|Haematologic Disease|Corneal Disease
Interventions: DRUG: Belantamab Mafodotin-Blmf|DRUG: Daratumumab|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Esomeprazole Na for Prevention of Rebleeding After Successful Endoscopic Therapy of a Bleeding Peptic Ulcer
Status: COMPLETED
Conditions: Bleeding Peptic Ulcer
Interventions: DRUG: Esomeprazole Na|DRUG: Cimetidine|DRUG: Esomeprazole Mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Regulation of Postprandial Nitric Oxide Bioavailability and Vascular Function By Dairy Milk
Status: COMPLETED
Conditions: Prediabetes
Interventions: OTHER: Glucose|OTHER: Glucose with Non-fat Milk|OTHER: Glucose with Whey Protein Isolate|OTHER: Glucose with Sodium Caseinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: EMISEP : Early Spinal Cord Lesions and Late Disability in Relapsing Remitting Multiple Sclerosis Patients
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: DEVICE: spinal cord MRI follow-up|OTHER: clinical follow-up|OTHER: brain MRI follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Yunzhi as Dietary Supplement in Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DIETARY_SUPPLEMENT: Yunzhi extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT