pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Calligraphy Writing for Cognitive and Emotional Enhancement Among Older MCI People
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Calligraphy Training|BEHAVIORAL: iPad Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcranial Direct Current Stimulation Associated With Physical Exercise: a Metaplasticity Study
Status: UNKNOWN
Conditions: Metaplasticity|Healthy Subjects
Interventions: BEHAVIORAL: Physical exercise|DEVICE: tDCS|BEHAVIORAL: Rest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Reprometabolic Syndrome Mediates Subfertility in Obesity
Status: COMPLETED
Conditions: Obesity|Infertility|Hypogonadotropic Hypogonadotropism|Hyperinsulinemia
Interventions: DRUG: Insulin|DRUG: Intralipid|DRUG: Dextrose|DRUG: Heparin|DRUG: GnRH|PROCEDURE: Hyperinsulinemic Euglycemic Clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Hemofiltration and Mannitol Treatment on Cardiopulmonary-Bypass Induced Immunosuppression
Status: UNKNOWN
Conditions: Inflammation
Interventions: DRUG: i.v. mannitol|PROCEDURE: hemofiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Ultraviolet Light And Vitamin D In Subjects With Fat Malabsorption Or After Gastric Bypass Surgery
Status: COMPLETED
Conditions: Vitamin D Deficiency|Gastrointestinal Diseases
Interventions: DEVICE: Sperti Lamp
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Compare the Menstrual Bleeding Profile Among Jaydess® and Copper Intrauterine Device (IUD) Users. COLIBRI STUDY (Copper and Levonorgestrel IUD Barcelona Research Initiative).
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Levonorgestrel (13,5 mg) intrauterine device|DEVICE: Cooper (380mm2) intrauterine device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of TACE Combined With Camrelizumab Plus Rivoceranib (Apatinib) in Patients With Incurable Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: TACE+Camrelizumab+Apatinib mesylate|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INCAGN01876 in Combination With Immunotherapy in Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
Status: WITHDRAWN
Conditions: Metastatic Head and Neck Squamous Cell Carcinoma|Advanced Malignancies|Recurrent Head and Neck Squamous Cell Carcinoma
Interventions: BIOLOGICAL: INCAGN01876|BIOLOGICAL: retifanlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Boron Phenylalanine With or Without Mannitol in Treating Patients With Glioblastoma Multiforme
Status: TERMINATED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: boron phenylalanine|DRUG: mannitol|OTHER: biologic sample preservation procedure|RADIATION: radiation therapy treatment planning/simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus Placebo for Patients With High-risk Localized Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Prostate Adenocarcinoma
Interventions: DRUG: Relacorilant|DRUG: Enzalutamide|OTHER: Placebo (Sugar Pill)|OTHER: Androgen Deprivation Therapy|PROCEDURE: Radical Prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Decade of Sleeve Gastrectomy: Analysis of Short and Long-term Outcome of 562 Patients
Status: COMPLETED
Conditions: Morbid Obesity|Obesity|Diabetes|Dyslipidemia|Hypertension
Interventions: PROCEDURE: Laparoscopic sleeve gastrectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety and Efficacy of Ruxolitinib Phosphate Cream Applied Topically to Adults With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Ruxolitinib 0.15% Cream QD|DRUG: Ruxolitinib 0.5% Cream QD|DRUG: Ruxolitinib 1.5% Cream QD|DRUG: Ruxolitinib 1.5% Cream BID|DRUG: Triamcinolone 0.1% Cream BID|DRUG: Vehicle Cream BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exogenous Ketone Supplementation and Exercise Performance
Status: UNKNOWN
Conditions: Ketonemia|Ketosis
Interventions: BEHAVIORAL: 20 km time trial|BEHAVIORAL: Wingate test|DIETARY_SUPPLEMENT: Ketone/Caffeine|DIETARY_SUPPLEMENT: Ketone|DIETARY_SUPPLEMENT: Water Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Remote Coaching for Supporting the Implementation of Depression Care in Primary Care in Rural India
Status: COMPLETED
Conditions: Depression|Depressive Disorder|Psychological|Noncommunicable Diseases
Interventions: OTHER: Enhanced Implementation Support|OTHER: Routine Implementation Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Rapid Rehabilitation to Treat Lower Extremity Trauma
Status: RECRUITING
Conditions: Lower Limb Trauma
Interventions: BEHAVIORAL: Promis Physical Function Questionnaire|BEHAVIORAL: L Test|BEHAVIORAL: Narrowing Beam Walking Test|BEHAVIORAL: PEQ-A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of 3D185 Monotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Cholangiocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Cholangiocarcinoma,Adult
Interventions: DRUG: 3D185
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of Remimazolam in Patients Undergoing Bronchoscopy
Status: COMPLETED
Conditions: Bronchoscopy
Interventions: DRUG: Remimazolam|DRUG: Placebo|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet-rich Plasma Injections for Persistent Medial Knee Pain After Total Knee Arthroplasty
Status: WITHDRAWN
Conditions: Knee Pain Chronic|Pes Anserinus Bursitis|Status-Post Total Knee Arthroplasty
Interventions: BIOLOGICAL: Ultrasound-guided platelet rich plasma injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EuroPainClinics® Study II (Prospective Trial)
Status: COMPLETED
Conditions: Lumbar Spinal Stenosis
Interventions: OTHER: Epiduroscopy|DRUG: Hyaluronic Acid|DRUG: DepoMedrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Intervention Study on the Effect of Brazilian Spinach Supplementation on Health Outcomes Among Type 2 Diabetes Patients in Hospital Universiti Sains Malaysia
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Althernanthera Sissoo|BEHAVIORAL: Dietary Consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety/Tolerability, pk, Effects on Histology, Clinical Parameters of Givinostat in Children With DMD
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy (DMD)
Interventions: DRUG: Givinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Effectiveness of the CorPath 200 System in Percutaneous Coronary Interventions (PCI)
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Disease|Myocardial Ischemia|Heart Diseases|Cardiovascular Diseases|Arteriosclerosis|Arterial Occlusive Diseases|Vascular Diseases
Interventions: DEVICE: CorPath robotic-assisted PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-In-Human SAD and MAD Study to Evaluate the Safety, Tolerability, PK and PD of SC Administered ALTB-268 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: ALTB-268|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamins D3 and K2 in uOc and Insulin Serum Levels in Patients With Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Bone Loss|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Supplementation with Vitamin D3 y K2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparison of Robot-assisted Single Site and Laparoscopic Single-incision Cholecystectomy for Benign Gallbladder
Status: UNKNOWN
Conditions: Benign Gallbladder Disease
Interventions: DEVICE: Da Vinci Single Site Robot-Assisted Cholecystectomy|DEVICE: Single Incision Laparoscopic Cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Red Grape Polyphenol Oral Administration to Women Affected by Nickel-mediated Allergic Contact Dermatitis
Status: COMPLETED
Conditions: Allergic Contact Dermatitis
Interventions: DIETARY_SUPPLEMENT: NaturOx Group (A)|OTHER: Placebo Group (B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Aspiration Risk Assessment by Gastric Ultrasound in eMErgency Surgery and ANesThetic Decision-making: The ARGUMENT Study
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Aspiration|Emergency Surgery
Interventions: PROCEDURE: GUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study on Dravet Syndrome (DS) and Lennox-Gastaut Syndrome (LGS) in Children, Teenagers and Adults in Portugal
Status: NOT_YET_RECRUITING
Conditions: Dravet Syndrome (DS)|Lennox-Gastaut Syndrome (LGS)
Interventions: OTHER: No Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of a Hospital Discharge Clinic to Improve Care Coordination and Reduce Rehospitalization in Low Income Adults
Status: COMPLETED
Conditions: Patient Readmission
Interventions: OTHER: Northwestern Follow Up Care Coordination|OTHER: Federally Qualified Health Center
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Soluble Beta-1,3/1,6-Glucan Compared to Placebo on Chronic Leg Ulcers in Diabetes Patients
Status: COMPLETED
Conditions: Foot Ulcer
Interventions: DRUG: Soluble beta-1,3/1,6-glucan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Neostigmine/Glyco-pyrrolate 50 Mikrogram/kg or Sugammadex 2 mg/kg for Reversal of Neuromuscular Blockade in Elderly Patients
Status: RECRUITING
Conditions: Neuromuscular Blockade, Residual
Interventions: DRUG: neostigmine/glycopyrrolate|DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic (PK) and Safety Study of Meropenem in Young Infants With Intra-abdominal Infections
Status: COMPLETED
Conditions: Necrotizing Enterocolitis|Intra-abdominal Infection
Interventions: DRUG: meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Glycocalyx in Abdominal Aortic Aneurysm
Status: UNKNOWN
Conditions: Abdominal Aortic Aneurism|Surgery|Ischemic Reperfusion Injury
Interventions: OTHER: Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pain Levels and Opioid Usage in Three Nerve Block Cohorts in Primary TKA
Status: WITHDRAWN
Conditions: Knee Arthropathy
Interventions: OTHER: preop ACB, followed by Intra-articular block during TKA surgery|OTHER: preop ACB+IPACK block|OTHER: preop ACB+IPACK block, followed by Intra-articular block during TKA surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Botox Instead of Strabismus Surgery (BISS)
Status: COMPLETED
Conditions: Acquired Esotropia
Interventions: DRUG: Botulinum toxin type A|PROCEDURE: Strabismus surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Branched-chain Amino Acid Supplementation for Cirrhotic Patients With Sarcopenia
Status: ENROLLING_BY_INVITATION
Conditions: Sarcopenia|Cirrhosis of the Liver
Interventions: DRUG: Branched-chain amino acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Locally Advanced Pancreatic Cancer
Status: UNKNOWN
Conditions: Locally Advanced Pancreatic Cancer
Interventions: DRUG: Gemcitabine|DRUG: Gemcitabine, Oxaliplatin, 5-Fluorouracil, Leucovorin (GOFL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects With Heart Failure
Status: COMPLETED
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: DRUG: Omecamtiv Mecarbil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: fNIRS, Listening Effort, and Motivation
Status: NOT_YET_RECRUITING
Conditions: Hearing Loss
Interventions: DEVICE: Hearing aids (omnidirectional)|DEVICE: Hearing aids (directional)|OTHER: Unaided
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Breathing-based Leg Resistance Exercise Improves Wound Healing, Blood Sugar and Quality of Life for Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot|Resistance Exercise|Wound Healing|Hyperglycemia|Quality of Life
Interventions: BEHAVIORAL: leg resistance combined with breathing exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bioequivalence of Fluzoparib(SHR3162) Study on Healthy Chinese Adult Subjects
Status: COMPLETED
Conditions: Healthy Adult Subjects
Interventions: DRUG: Fluzoparib|DRUG: Fluzoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: 1HP Versus 3HR in the Treatment of Tuberculosis Infection in Vietnam
Status: NOT_YET_RECRUITING
Conditions: Tuberculosis Infection
Interventions: DRUG: Isoniazid|DRUG: Rifapentine|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of the AccuCinch® System for Left Ventricular Reshaping of the Mitral Apparatus to Reduce Functional Mitral Regurgitation and Improve Left Ventricular Function
Status: COMPLETED
Conditions: Severe Functional Mitral Regurgitation and Heart Failure
Interventions: DEVICE: GDS Accucinch System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Transversus Thoracic Muscle Plane Block on Post-sternotomy Pain
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: OTHER: transversus thoracic muscle plane block|OTHER: general anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy to Treat Musculoskeletal Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcoma, Ewing's|Rhabdomyosarcoma|Soft Tissue Sarcoma|Musculoskeletal Tumors
Interventions: RADIATION: image-guided radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Z650 in Treating Patients With Metastatic or Recurrent Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: Z650|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study for HLA Identical Living Donor Renal Transplant Recipients
Status: COMPLETED
Conditions: Renal Transplant
Interventions: DRUG: calcineurin inhibitor|DRUG: sirolimus|DRUG: mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mitoxantrone ± Cetuximab 2nd Line Androgen Independent Prostate Cancer (AIPC)
Status: COMPLETED
Conditions: Androgen-independent Prostate Cancer
Interventions: DRUG: cetuximab|DRUG: Mitoxantrone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Niacin/Laropiprant on Postprandial Lipoprotein Metabolism in Patients With Dyslipoproteinemia
Status: TERMINATED
Conditions: Hyperlipoproteinemia|Metabolic Syndrome
Interventions: DRUG: Niacin/ Laropiprant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Randomised Study: Metabolic and Functional Effects of Bariatric Surgery Accessed Using PET and MRI.
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: PROCEDURE: Bariatric surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Skin Preparation for Elective Foot and Ankle Surgery
Status: RECRUITING
Conditions: Microbial Colonization|Foot and Ankle Disorders
Interventions: DRUG: Hibiclens|DRUG: Isopropyl Alcohol 70% Topical Application Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Empagliflozin vs Linagliptin on Glycemic Outcomes,Renal Outcomes & Body Composition in Renal Transplant Recipients With Diabetes Mellitus
Status: RECRUITING
Conditions: Kidney Transplant; Complications|Diabetes Mellitus
Interventions: DRUG: Empagliflozin 25 MG|DRUG: Linagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Botulinum Type A Products in the Treatment of Blepharospasm
Status: COMPLETED
Conditions: Blepharospasm
Interventions: BIOLOGICAL: Botulinum Toxin Type A 900kDa|BIOLOGICAL: Botulinum Toxin Type A 150kDa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-flow Nasal Oxygenation During Deep Sedation in Pediatric Dental Patients
Status: RECRUITING
Conditions: Deep Sedation|Dental Treatment|Pediatric Patients
Interventions: DEVICE: High-flow nasal oxygenation device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: ACEI/CCB Versus ACEI/DIU Combination Antihypertensive Therapy in Chinese Hypertensive Patients (ACvAD)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: ACEI/CCB|DRUG: ACEI/DIU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Prospective Trial Comparing Polyethylene Glycol and Sodium Picosulphate With Magnesium Citrate
Status: COMPLETED
Conditions: Colorectal Cancer|Colon Adenoma
Interventions: DRUG: Polyethylene glycol|DRUG: Polyethylene glycol|DRUG: Sodium picosulphate with magnesium citrate|DRUG: Sodium picosulphate with magnesium citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Added Value of a Neuroendocrine Test Battery in the Response to Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment
Status: RECRUITING
Conditions: Major Depression
Interventions: PROCEDURE: Repetitive transcranial magnetic stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Study for Actinic Cheilitis Comparing Imiquimod 5% and Photodynamic Therapy
Status: COMPLETED
Conditions: Actinic Cheilitis
Interventions: DRUG: Imiquimod 5%|PROCEDURE: Photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Safety Extension Trial of Asenapine in Bipolar 1 Disorder Participants Who Completed Protocol P05691 (P05692)
Status: COMPLETED
Conditions: Bipolar I Disorder
Interventions: DRUG: asenapine|DRUG: asenapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Safety and Tolerability of Ezetimibe (SCH 58235, MK-0653) With Atovastatin (P02154, MK-0653-017)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Ezetimibe|DRUG: Atovastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Surgical Technique in Intramedullary Tibia Nailing, Using Trigen META Tibia Nails
Status: COMPLETED
Conditions: Tibial Fractures
Interventions: PROCEDURE: Semi-extended Surgical Technique|PROCEDURE: Standard Surgical Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Efficacy and Safety of Bevacizumab in Untreated Patients With Locally Advanced Cervical Cancer
Status: UNKNOWN
Conditions: Disease Free Survival
Interventions: DRUG: bevacizumab|DRUG: DDP|DRUG: Docetaxel|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RAPID-POP a Randomized Controlled Trial
Status: RECRUITING
Conditions: Myocardial Infarction, Acute
Interventions: PROCEDURE: Primary Percutaneous Coronary Intervention (PPCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Antioxidants on Prostate Tumors in Men Undergoing Radical Prostatectomy for Prostate Cancer
Status: COMPLETED
Conditions: Cancer of the Prostate|Prostate Cancer|Prostatic Neoplasms
Interventions: DIETARY_SUPPLEMENT: Lycopene, Vitamin D3, Selenium, Green Tea Extract, Vitamin E|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Proper Breakfast Times on Cognitive Function
Status: NOT_YET_RECRUITING
Conditions: Eating, Time Restricted|Cognitive Change|Blood Pressure|Nutrition, Healthy
Interventions: OTHER: breakfast 6.30 am|OTHER: breakfast 7.31 am
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ultrasound Guided Caudal Block Versus Quadratus Lumborum Block in Children
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Hernioraphy/Caudal block|PROCEDURE: Hernioraphy/Quadratus Lumborum block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of GR1802 Injection in Patients With Atopic Dermatitis
Status: NOT_YET_RECRUITING
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: GR1802 injection|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Palifermin for Patients Receiving Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Mucositis
Interventions: DRUG: Palifermin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Gabapentin Versus Placebo on Buprenorphine Detoxification of Opioid-dependent Individuals
Status: COMPLETED
Conditions: Opioid Dependence|Opioid Withdrawal|Opioid Detoxification
Interventions: DRUG: Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy, Safety, and Tolerability of MT-7117 in Subjects With Diffuse Cutaneous Systemic Sclerosis
Status: COMPLETED
Conditions: Diffuse Cutaneous Systemic Sclerosis
Interventions: DRUG: MT-7117|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post Spinal Hemodynamic Changes in Aortic Stenosis and Mitral Regurgitation by VIS Index and Echocardiography
Status: RECRUITING
Conditions: Severe Aortic Valve Stenosis|Severe Mitral Valve Regurgitation
Interventions: PROCEDURE: Cardiac valve replacement surgery under high spinal anesthesia combined with light general anesthesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Single Ascending and Repeated Dose Study of Oral ZF874 in Healthy Volunteers and PiXZ Subjects
Status: TERMINATED
Conditions: Alpha1 Anti-Trypsin Deficiency
Interventions: DRUG: ZF874|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TFBC Combined With UCBT in the Treatment of High-risk Malignant Hematological Diseases
Status: RECRUITING
Conditions: Hematopoietic Stem Cell Transplantation|Malignant Hematological Diseases
Interventions: PROCEDURE: Umbilical Cord Blood Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of 4% Nebulized Lignocaine vs. 10% Lignocaine Spray in Patients Undergoing Flexible Bronchoscopy
Status: COMPLETED
Conditions: Patients With Indication for Flexible Bronchoscopy
Interventions: DRUG: Nebulized Lignocaine|DRUG: Lignocaine spray|DRUG: Combined spray and nebulization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Letrozole in Preventing Recurrence of Endometrioma Following Laparoscopic Ovarian Cystectomy
Status: RECRUITING
Conditions: Endometriotic Cyst of Ovary
Interventions: DRUG: Letrozole|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pembrolizumab in Advanced Hepatocellular Carcinoma as Second-line Treatment After Failure of Sorafenib
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Effect of Levodopa-Carbidopa Intestinal Gel (LCIG) Therapy Relative to That of Optimized Medical Treatment (OMT) on Non-motor Symptoms (NMS) Associated With Advanced Parkinson's Disease (PD)
Status: COMPLETED
Conditions: Advanced Parkinson's Disease
Interventions: DRUG: Optimized Medical Treatment|DRUG: Levodopa-Carbidopa Intestinal Gel|DEVICE: Nasojejunal (NJ) tube|DEVICE: Percutaneous endoscopic gastrostomy with a jejunal (PEG-J) tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Clinical Trial of Recombinant Novel Coronavirus (COVID-19) Vaccine (Adenovirus Type 5 Vector) for Inhalation
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) for Inhalation|BIOLOGICAL: Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector)|BIOLOGICAL: Placebo for Inhalation|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Botulinum Toxin Type A to Treat Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: botulinum toxin Type A|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Polyethylene Wear, Migration and Clinical Outcome in Total Hip Replacement
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Hip|Osteoarthritis
Interventions: DEVICE: E-Poly liner|DEVICE: ArComXL liner|DEVICE: 32 mm femoral head|DEVICE: 36 mm femoral head
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of CoQ10 Plus Selenium Supplementation on Clinical Outcomes and Biochemical Markers in ME/CFS (CoSeME Study)
Status: COMPLETED
Conditions: Myalgic Encephalomyelitis
Interventions: DIETARY_SUPPLEMENT: CoQ10 plus Selenium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Monitoring of Patient Reported Outcomes to Improve the Efficacy of the Acute Phase Radiotherapy Review Process
Status: RECRUITING
Conditions: Prostate Cancer|Breast Cancer
Interventions: OTHER: Remote monitoring PROs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Topical Sirolimus in Cutaneous Lymphatic Malformations
Status: RECRUITING
Conditions: Vascular Malformations|Lymphatic Malformation
Interventions: DRUG: Topical 0.1% Sirolimus|DRUG: Topical Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double Blind RCT of Bicifadine SR in Outpatients With Chronic Neuropathic Pain Associated With Diabetes
Status: UNKNOWN
Conditions: Diabetic Peripheral Neuropathy
Interventions: DRUG: Bicifadine|DRUG: Bicifadine|DRUG: Bicifadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sympathetic Nerve Activity in Renal Failure
Status: WITHDRAWN
Conditions: Chronic Kidney Disease|Hypertension
Interventions: DRUG: Rilmenidine|DRUG: Nitrendipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of ElDOA and Post-Facilitation Stretching Technique on Pain and Disability in Patients With Text Neck Syndrome
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: ELDOA method|OTHER: Post-facilitation stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S0800, Nab-Paclitaxel, Doxorubicin, Cyclophosphamide, and Pegfilgrastim With or Without Bevacizumab in Treating Women With Inflammatory or Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: bevacizumab|BIOLOGICAL: pegfilgrastim|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: paclitaxel albumin-stabilized nanoparticle formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MEDI9253 in Combination With Durvalumab in Select Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: BIOLOGICAL: MEDI9253|BIOLOGICAL: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion
Status: RECRUITING
Conditions: Delirium|Pain, Back|Spinal Fusion|Thoracolumbar Interfascial Plane Block
Interventions: DRUG: Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine|DIAGNOSTIC_TEST: Blood Test|OTHER: 3D CAM Delirium Severity Scoring|OTHER: Generalized Anxiety Disorder 7-item (GAD-7) scale|OTHER: Numerical Rating Score (NRS)|OTHER: PROMIS-Pain Interference|OTHER: Oswestry Disability Index (ODI)|OTHER: Saint Louis University Mental Status Examination (SLUMs)|OTHER: Delirium Rating Scale-Revised-98 (DRS)|OTHER: Telephone Interview for Cognitive Status - Modified (TICS-M)|OTHER: Opioid Equivalents measured by Morphine Milligram Equivalents (MME)|OTHER: Patient Health Questionnaire depression scale (PHQ-8)|OTHER: Pain Catastrophizing|OTHER: Fear Avoidance Beliefs Questionnaire (FABQ)|OTHER: Opioid Side Effects and Likeability Questionnaire|OTHER: Daily Pain Trajectory|OTHER: Tampa Scale of Kinesiophobia|OTHER: Quality of Recovery 15
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Paracervical Block for Pain Control With Osmotic Dilator Placement
Status: TERMINATED
Conditions: Abortion Late|Pain
Interventions: PROCEDURE: Local anesthetic for tenaculum placement|PROCEDURE: Sham|PROCEDURE: Paracervical Block|PROCEDURE: Dilator Placement|BEHAVIORAL: Post-procedural assessment|DRUG: Preprocedural pain control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Iron Repletion in Chronic Cough and Iron Deficiency
Status: COMPLETED
Conditions: Cough|Laryngeal Disease|Bronchial Disease|Iron Deficiency
Interventions: DRUG: iron sulphate|DRUG: antiH1-histamine, proton pump inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Telmisartan Between Telmisartan 80 mg/Amlodipine 5 mg/Hydrochlorothiazide 12.5 mg (T80/A5/H12.5 mg) Fixed-dose Combination (FDC) Tablet and T80/H12.5 mg Tab and A5 mg (Encap A2.5 mg Tab x2) Concomitant Use
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Amlodipine 5mg capsule|DRUG: T80/H12.5 mg FDC tablet|DRUG: T80/A5/H12.5 mg FDC tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, And Immunogenicity Study Of ACC-001 In Japanese Subjects With Mild To Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: ACC-001|OTHER: QS-21|OTHER: QS-21
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Tissue Acquiring Techniques During EUS Guided Biopsies of Solid Tumors.
Status: TERMINATED
Conditions: Solid Tumor
Interventions: PROCEDURE: Endoscopic ultrasound guided fine needle biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Motor Task Performance Under Visual and Auditory Feedback Post Stroke: a Randomized Crossover Trial
Status: COMPLETED
Conditions: Ischemic Stroke|Upper Extremity Paresis
Interventions: DEVICE: SWORD|OTHER: Exercise with biofeedback|OTHER: exercise without biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Intra-Aortic Balloon Pump (IABP) in Coronary Artery Bypass Grafting (CABG) Operations in Patients With Severely Depressed Left Ventricular Function
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Artery Bypass Grafting
Interventions: PROCEDURE: IABP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Evaluation of Efficacy and Safety of Stylage® XL Lidocaïne for the Restoration and/or Augmentation of Facial Volume
Status: COMPLETED
Conditions: Aging|Healthy
Interventions: DEVICE: Stylage® XL Lidocaïne
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lung Volume Change Between Noninvasive Positive Pressure Ventilation by Nasal Pillow and High Flow Nasal Cannula
Status: UNKNOWN
Conditions: Respiratory Failure
Interventions: DEVICE: Nasal Pillow CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
Status: RECRUITING
Conditions: Type2Diabetes|ASCVD
Interventions: DRUG: SGLT2 inhibitor|DRUG: GLP-1 receptor agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Osimertinib Then Chemotherapy in EGFR-mutated Lung Cancer With Osimertinib Third-line Rechallenge
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Osimertinib First-Line|DRUG: Platinum + Pemetrexed Chemotherapy Second-Line|DRUG: Osimertinib Third-Line
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-escalation Study of Quarfloxin in Patients With Advanced Solid Tumors or Lymphomas
Status: TERMINATED
Conditions: Advanced Solid Tumors|Lymphoma
Interventions: DRUG: Quarfloxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Videogame for the Prevention of Doping and Supplement Abuse in Teenage Athletes
Status: UNKNOWN
Conditions: Doping in Sport|Performance Enhancing Product Use
Interventions: BEHAVIORAL: Videogame|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Analgesic Effect of Inhaled Lavender Essential Oil for Clipping of Tongue-ties
Status: COMPLETED
Conditions: Ankyloglossia
Interventions: DIETARY_SUPPLEMENT: Lavender essential oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of rhLactoferrin on Chronic Inflammation in the Elderly
Status: COMPLETED
Conditions: Inflammation|Cognitive Deterioration
Interventions: DRUG: rhLactoferrin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intranasal Neurostimulation in Ameliorating Symptoms of Neuropathic Corneal Pain
Status: TERMINATED
Conditions: Cornea
Interventions: DEVICE: TrueTear™ intranasal neurostimulator (ITN)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Pharmacokinetics and Safety of Remibrutinib in Participants With Hepatic Impairment Compared With Matched Healthy Participants
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Part 1; LOU064 (Remibrutinib)|DRUG: Part 2; LOU064 (Remibrutinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects on Cognitive Function of Levetiracetam (Keppra®) Compared to Carbamazepine (Tegretol®, Carmazepine®) as Monotherapy for Children With Partial Seizure; A Multicentric Randomized Controlled Study
Status: COMPLETED
Conditions: Focal Epilepsy
Interventions: DRUG: Levetiracetam|DRUG: Carabamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbiome-Tailored Food Products Based On Typical Mediterranean Diet Components
Status: COMPLETED
Conditions: Microbiota|Overweight and Obesity|Metabolic Complication
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: SuperFood
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Amlodipine for Myocardial Iron in Thalassemia
Status: COMPLETED
Conditions: Thalassemia
Interventions: DRUG: Standard Chelation|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Single Dose Daptomycin in Pediatric Patients With Gram-positive Infection for Which They Are Receiving Standard Antibiotics
Status: COMPLETED
Conditions: Gram-positive Bacterial Infections
Interventions: DRUG: daptomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Biofeedback on Postoperative Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Postoperative Pain
Interventions: BEHAVIORAL: Respiratory biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The BIOPRES Trial: Transrectal BIOpsies of the PRostate: End Versus Side-firing
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DEVICE: TRUS probe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: RCT of QPS vs General Information Sheet
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Neoplasm|Caregiver|Physician
Interventions: OTHER: Informational Intervention|OTHER: Informational Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open-label Study of Levetiracetam Intravenous Infusion in Children (4-16 Years Old) With Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study to Evaluate Long-term Clinical Outcomes of the GTS Cementless Femoral Stem
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Hip
Interventions: DEVICE: GTS cementless stem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Refinement and Assessment of New MRI Technologies for Thoracic/ Cardiovascular Exams
Status: COMPLETED
Conditions: Magnetic Resonance Imaging (MRI) of the Chest
Interventions: PROCEDURE: MRI -Clinical|PROCEDURE: MRI-Research
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD) and Efficacy of Repeat Doses of GSK2982772 in Subjects With Moderate to Severe Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: GSK2982772 60 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT