pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Blinatumomab, Methotrexate, Cytarabine, and Ponatinib in Treating Patients With Philadelphia Chromosome-Positive, or BCR-ABL Positive, or Relapsed/Refractory, Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Acute Lymphoblastic Leukemia|BCR-ABL1 Fusion Protein Expression|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Philadelphia Chromosome Positive|Recurrent Acute Lymphoblastic Leukemia|Refractory Acute Lymphoblastic Leukemia|t(9;22)
Interventions: BIOLOGICAL: Blinatumomab|DRUG: Cytarabine|DRUG: Methotrexate|DRUG: Ponatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Three Different Final Irrigants and Showing Their Effects on the Success of Revascularization
Status: UNKNOWN
Conditions: Post-operative Pain
Interventions: DRUG: Propolis|DRUG: Nano-propolis|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Prospective, Randomized, Multicenter, Comparative Study of the Efficacy of Imatinib Resumption Combined With Atezolizumab Versus Imatinib Resumption Alone in Patients With Unresectable Advanced Gastrointestinal Stromal Tumors (GIST) After Failure of Standard Treatments
Status: RECRUITING
Conditions: Unresectable Gastrointestinal Stromal Tumor (GIST)|Locally Advanced Gastrointestinal Stromal Tumor (GIST)|Metastatic Gastrointestinal Stromal Tumor
Interventions: DRUG: Atezolizumab 1200 mg|DRUG: Imatinib 400 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct-current Stimulation (tDCS) Efficacy in Refractory Cancer Pain.
Status: RECRUITING
Conditions: Cancer Pain|Refractory Pain
Interventions: DEVICE: Active Transcranial Direct Current Stimulation|DEVICE: Sham Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Modified Müller's Muscle-conjunctival Resection Internal Ptosis Repair Using Fibrin Glue
Status: UNKNOWN
Conditions: Ptosis, Eyelid|Ptosis; Eyelid, Congenital|Surgical Procedure, Unspecified
Interventions: DEVICE: Using of Tisseel fibrin glue|OTHER: Using sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Zip® Surgical Skin Closure Device vs. Staples for Skin Closure in Subjects Having Undergone Bilateral Knee Arthroplasty
Status: COMPLETED
Conditions: Arthroplasty, Knee Replacement|Wound Healing
Interventions: DEVICE: Zip Surgical Skin Closure|DEVICE: Steel Staples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Multi-Center, Single-Arm Study of the Veriset™ Hemostatic Patch in Controlling Bleeding in Soft Tissue
Status: COMPLETED
Conditions: Non-emergent, Soft Tissue Procedures, Performed Via an Open Approach
Interventions: DEVICE: Veriset™ Hemostatic Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Semi-blunt Needles: is Outcome Better?
Status: COMPLETED
Conditions: Chronic Hemodialysis Patients|Vascular Abord: Native Arterio-venous Fistula|Buttonhole Cannulation
Interventions: PROCEDURE: Buttonhole cannulation with semi-blunt needles
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Peripheral Neuropathy Symptoms on Temporomandibular Joint Functionality
Status: COMPLETED
Conditions: Diabete Type 2
Interventions: OTHER: Michigan Neuropathy Screening Instrument|OTHER: Numeric Pain Scale|OTHER: Mandibular Function Disorder Questionnaire|OTHER: Fonseca Anamnestic Index|OTHER: Ferrans&Powers Quality of Life Index Diabetes Version
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Weaning From Incubator To Crib
Status: RECRUITING
Conditions: Hypothermia, Newborn|Body Temperature Changes|Newborn Thermal Injury
Interventions: RADIATION: Weaning incubator (heat) at an lower postnatal weight
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of GSK Biologicals' Staphylococcal Investigational Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Infections, Staphylococcal
Interventions: BIOLOGICAL: Staphylococcal investigational vaccine GSK2392103A|BIOLOGICAL: Staphylococcal investigational vaccine GSK2392105A|BIOLOGICAL: Staphylococcal investigational vaccine GSK2392106A|BIOLOGICAL: Staphylococcal investigational vaccine GSK2392019A|DRUG: Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy, Safety and Immunogenicity of Inactivated SARS-CoV-2 Vaccines (Vero Cell) to Prevent COVID-19 in Healthy Adult Population In Peru Healthy Adult Population In Peru
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Inactivated SARS CoV 2 vaccine (Vero cell) Wuhan/Beijing/Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate Efficacy, Tolerability and Safety of ABY-035 in Patients With Active Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: BIOLOGICAL: ABY-035|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Rifaximin Vaginal Tablets in Bacterial Vaginosis
Status: TERMINATED
Conditions: BACTERIAL VAGINOSIS
Interventions: DRUG: RIFAXIMIN VAGINAL TABLET 25 MG|DRUG: RIFAXIMIN VAGINAL TABLET 100 MG|DRUG: PLACEBO VAGINAL TABLET|DRUG: METROGEL VAGINAL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of SHR-A1921 Combined Adebrelimab in HR-positive, HER2-negative Advanced Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced Breast Cancer|Hormone-receptor-positive Breast Cancer|Human Epidermal Growth Factor 2 Negative Carcinoma of Breast
Interventions: DRUG: SHR-A1921|DRUG: Adebrelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Multiple Protein and Molecular Biomarkers to Estimate Risk of Cancer in Gynecology Patients Presenting With a Pelvic Mass.
Status: COMPLETED
Conditions: Ovarian Neoplasms
Interventions: PROCEDURE: Pelvic imaging|PROCEDURE: Blood draw|PROCEDURE: Imaging guided biopsy, surgical biopsy or surgical excision
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: AZD8075 Single Ascending Dose Study
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: AZD8075|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Liraglutide as add-on to Metformin Compared to Either Liraglutide or Metformin Alone, or to a Combination of Metformin and a SU (Sulphonylurea) Agent in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide|DRUG: metformin|DRUG: placebo|DRUG: placebo|DRUG: glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Predicting Response to Chemotherapy in Samples From Young Patients With Osteosarcoma
Status: COMPLETED
Conditions: Localized Osteosarcoma|Metastatic Osteosarcoma|Osteoblastic Osteosarcoma|Recurrent Osteosarcoma
Interventions: OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Educational Program in Younger Women Who Have Recently Finished Treatment for Stage I or Stage II Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: BEHAVIORAL: Education Intervention|BEHAVIORAL: Nutrition Education Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Utility of Single-dose Oral Antibiotic Prophylaxis in Prevention of Surgical Site Infection in Dermatologic Surgery
Status: RECRUITING
Conditions: Surgical Site Infection
Interventions: DRUG: Cephalexin|OTHER: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of TissueGene-C to Degenerative Arthritis
Status: COMPLETED
Conditions: Degenerative Arthritis
Interventions: BIOLOGICAL: TissueGene-C|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial of Zesteem (Estradiol) in Healing of Split Thickness Skin Graft Donor Sites
Status: COMPLETED
Conditions: Burn|Trauma|Varicose Ulcer
Interventions: DRUG: estradiol (Zesteem)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Statins and Endothelial Function in Patients With Coarctation of the Aorta
Status: TERMINATED
Conditions: Coarctation of the Aorta
Interventions: DRUG: atorvastatin|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mobile Apps for Preschool Parents (MAPP) Study
Status: RECRUITING
Conditions: Obesity, Childhood|Nutrition, Healthy|Physical Inactivity|Sleep, Inadequate
Interventions: BEHAVIORAL: Children Eating Well (CHEW) mobile app|BEHAVIORAL: Beanstalk mobile app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Effect of Drug-Related Problems in Pulmonary Embolism
Status: COMPLETED
Conditions: Pulmonary Thromboembolisms
Interventions: BEHAVIORAL: Intervention Group: Group to which the clinical pharmacist makes recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Birinapant in Combination With Conatumumab in Subjects With Relapsed Ovarian Cancer
Status: COMPLETED
Conditions: Relapsed Epithelial Ovarian Cancer|Relapsed Primary Peritoneal Cancer|Relapsed Fallopian Tube Cancer
Interventions: DRUG: Birinapant|DRUG: Conatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing a Culturally Adapted Intervention for Latino Youth Transitioning to Adulthood
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Launching! to Adulthood (¡Iniciando! la Adultez) program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo Controlled Study to Assess the Efficacy and Safety of Rapamycin in Drug Resistant Epilepsy Associated With Tuberous Sclerosis Complex
Status: RECRUITING
Conditions: Tuberous Sclerosis Complex
Interventions: OTHER: Rapamycin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glycine and D-Cycloserine in Schizophrenia
Status: WITHDRAWN
Conditions: Schizophrenia
Interventions: DRUG: D-cycloserine|DRUG: Glycine|DRUG: Clozapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Pathologic Studies in Non-Hodgkin's Lymphoma Patients Receiving Antibody Treatment
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|Lymphomas: Non-Hodgkin|Lymphomas: Non-Hodgkin Cutaneous Lymphoma|Lymphomas: Non-Hodgkin Diffuse Large B-Cell|Lymphomas: Non-Hodgkin Follicular / Indolent B-Cell|Lymphomas: Non-Hodgkin Mantle Cell|Lymphomas: Non-Hodgkin Marginal Zone|Lymphomas: Non-Hodgkin Peripheral T-Cell|Lymphomas: Non-Hodgkin Waldenstr Macroglobulinemia
Interventions: DRUG: Rituximab|DRUG: Epratuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy of Cognitive Rehabilitation Using Virtual Reality and Computer-based Cognitive Stimulation on Cognitive Impairment Associated to Movement Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease|Huntington Disease
Interventions: DEVICE: Immersive Virtual Reality (Parkinson's disease)|DEVICE: Computer-based cognitive rehabilitation (Parkinson's disease)|DEVICE: Computer-based cognitive rehabilitation (Huntington's disease)|BEHAVIORAL: Music-therapy (Huntington's disease)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of a Statin + Erlotinib for Advanced Solid Malignancies With Focus on Squamous Cell Carcinomas and NSCLC
Status: COMPLETED
Conditions: Squamous Cell Carcinoma|Non-Small Cell Lung Cancer
Interventions: DRUG: Erlotinib + Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Different Airway Devices on Middle Ear Pressure in Pediatric Patients
Status: UNKNOWN
Conditions: Local Pressure Effects|Simple Ear
Interventions: DEVICE: Laryngeal mask classical application|DEVICE: I-gel laryngeal mask application|DEVICE: Cobra laryngeal mask application|DEVICE: Supreme laryngeal mask application|DEVICE: Proseal laryngeal mask application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PMCF of Rotarex®S & Aspirex®S Catheters in Treating Thrombotic Occlusion of Arteriovenous Graft
Status: COMPLETED
Conditions: Arteriovenous Graft Thrombosis
Interventions: DEVICE: Atherectomy/Thrombectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Effectiveness Metformin for Deceasing Proliferative Marker in Endometrial Cancer Cells
Status: COMPLETED
Conditions: Metformin|CA Endometrium
Interventions: DRUG: Metformin Hydrochloride 850 MG|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tiotropium/Salmeterol Inhalation Powder in COPD
Status: TERMINATED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium/Salmeterol|DRUG: Tiotropium/Salmeterol QD + Salmeterol|DRUG: Placebo|DRUG: Salmeterol|DRUG: Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Improvement in Pain and Function Following a Physiotherapy Program in Older Adults With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Therapeutic exercise|DEVICE: Dry needling|DEVICE: Sham dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compass - Randomised Controlled Trial of Primary HPV Testing for Cervical Screening in Australia
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer of the Cervix|Cervical Intraepithelial Neoplasia
Interventions: DEVICE: Molecular testing for HPV|DEVICE: Liquid Based Cytology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Self-Administered Transcranial Direct Current Stimulation for Pain in Older Adults With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy for Insomnia (CBTI) in GERD Patients With Insomnia
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: BEHAVIORAL: Web-based CBTI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells for the Treatment of Pouch Fistulas in Crohn's
Status: WITHDRAWN
Conditions: Crohn's Disease|Fistula|Anal Fistula|Pouch, Ileal|Pouches, Ileoanal
Interventions: DRUG: mesenchymal stem cells (MSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Study the Effects of Bobath Therapy With and Without EMG Biofeedback Therapy in Stroke Patients
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: EMG Biofeedback therapy and Bobath therapy|OTHER: Bobath therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Extension Study of GI198745 to Treat Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia|Prostatic Hyperplasia
Interventions: DRUG: GI198745 0.05mg|DRUG: GI198745 0.5mg|DRUG: GI198745 2.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of IDP-118 Lotion to Ultravate® in the Treatment of Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: IDP-118 Vehicle Lotion|DRUG: IDP-118 Vehicle Cream|DRUG: IDP-118 Lotion|DRUG: Ultravate Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tart Cherry Supplementation & Gut Microbiome and Inflammation
Status: COMPLETED
Conditions: Inflammation|Glucose Regulation|Sleep
Interventions: DIETARY_SUPPLEMENT: Tart cherry juice concentrate|DIETARY_SUPPLEMENT: Juice placebo|DIETARY_SUPPLEMENT: Freeze dried tart cherry powder|DIETARY_SUPPLEMENT: Capsule placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low-dose IL-2 Treatment on Behcet's Disease
Status: COMPLETED
Conditions: Behcet's Disease
Interventions: DRUG: Low-dose IL-2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Assess the Safety and Effectiveness of Anti-Ageing and Skin Brightening Gel
Status: COMPLETED
Conditions: Wrinkle|Pigment Skin|Aging
Interventions: OTHER: Placebo|OTHER: Anti-Ageing and Skin Brightening Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)
Status: RECRUITING
Conditions: Gastroesophageal Junction|Gastroesophageal Adenocarcinoma|Esophageal Neoplasms|Esophageal Cancer
Interventions: BIOLOGICAL: Ramucirumab|DRUG: Paclitaxel|BIOLOGICAL: MK-2870
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors
Status: RECRUITING
Conditions: Cervical Cancer|Colorectal Cancer|Esophageal Cancer|Gastric Cancer|Glioblastoma Multiforme|Cholangiocarcinoma|Hepatocellular Carcinoma|Head and Neck Squamous Cell Carcinoma|Nasopharyngeal Carcinoma|Non Small Cell Lung Cancer|Small Cell Lung Cancer|Epithelial Ovarian Cancer|Pancreatic Ductal Adenocarcinoma|Soft Tissue Sarcoma
Interventions: DRUG: 89Zr-DFO-girentuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Breast Cancer|Glioblastoma|Head and Neck Squamous Cell Carcinoma|Malignant Mesothelioma|Non-small Cell Lung Cancers|Sarcoma|Endometrial Cancer
Interventions: DRUG: PRT3645
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Three Different Minimally Invasive Techniques for Management of Enamel Opacities in Patients With Molar Incisor Hypomineralization "Randomized Controlled Clinical Trial"
Status: NOT_YET_RECRUITING
Conditions: Molar Incisor Hypomineralization
Interventions: DRUG: Resin infiltration|DRUG: Resin modified glass ionomer varnish|DRUG: Light cured giomer varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PDE-4 Inhibitor Roflumilast and Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: PCOS|Obesity
Interventions: DRUG: metformin|DRUG: metformin and roflumilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lactobacillus Paracasei PS23 on Improving Aging and Muscle Loss in the Elderly
Status: COMPLETED
Conditions: Elderly|Muscle Loss|Depression|Anxiety
Interventions: DIETARY_SUPPLEMENT: Probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Subarachnoidal Anesthesia: Dexmedetomidine vs Fentanyl Plus Hyperbaric Bupivacaine for Lower Abdomen Surgery
Status: COMPLETED
Conditions: Dexmedetomidine in Subarachnoidal Anesthesia
Interventions: DRUG: Dexmedetomidine and bupivacaine|DRUG: Fentanyl and bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Advancing Brain Outcomes in Pediatric Critically Ill Patients Sedated With Volatile AnEsthestic Agents
Status: RECRUITING
Conditions: Intensive Care Units, Pediatric|Anesthetics, Inhalation
Interventions: DRUG: Isoflurane Inhalant Product|DRUG: Sevoflurane inhalant product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Imaging With FAPI-PET/MRI in Breast Carcinoma-In-Situ for Detection of Occult Invasive Cancer
Status: NOT_YET_RECRUITING
Conditions: Carcinoma, Intraductal, Noninfiltrating
Interventions: DRUG: [68Ga]Ga-FAPI-46
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Hydroxyurea and Magnesium Pidolate for Treatment of Sickle Cell Disease
Status: COMPLETED
Conditions: Anemia, Sickle Cell
Interventions: DRUG: Magnesium Pidolate, Hydroxyurea
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance Treatment for Ovarian Carcinoma in Remission by an Antiangiogenic Treatment Strategy
Status: TERMINATED
Conditions: Ovarian Carcinoma
Interventions: DRUG: Cytophosphan, Celecoxib, Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of BCX7353 to Prevent Angioedema Attacks in Subjects With Hereditary Angioedema
Status: COMPLETED
Conditions: Hereditary Angioedema (HAE)
Interventions: DRUG: BCX7353|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: High-Density Spinal Cord Stimulation for the Treatment of Chronic Intractable Pain Patients
Status: TERMINATED
Conditions: Pain, Intractable
Interventions: DEVICE: Spinal Cord Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Motivation Project: Testing Intervention Components for the Smoker Who is Unwilling to Quit
Status: COMPLETED
Conditions: Smoking|Motivation|Smoking Cessation
Interventions: DRUG: Nicotine Mini-Lozenge|BEHAVIORAL: Behavioral Reduction Counseling|BEHAVIORAL: 5Rs Motivation Counseling|BEHAVIORAL: Behavioral Activation Counseling|OTHER: No Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ureteric Stent Tethers on Patient Symptoms and Urinary Infection
Status: TERMINATED
Conditions: Kidney Stone
Interventions: DEVICE: Double J-stent with a long tether|DEVICE: Double J-stent without a long tether
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Quinine Sulfate Capsules Under Fasting and Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Quinine Sulfate Capsules 324 mg|DRUG: Quinine Sulphate Tablets 300 mg|DRUG: Quinine Sulfate Capsules 324 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Doxycycline and Tauroursodeoxycholic Acid (Doxy/TUDCA) Plus Standard Supportive Therapy Versus Standard Supportive Therapy Alone in Cardiac Amyloidosis Caused by Transthyretin
Status: COMPLETED
Conditions: TTR Cardiac Amyloidosis
Interventions: DRUG: Doxycycline and tauroursodeoxycholic acid|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2a/b Study of the Efficacy and Safety of Subcutaneous Amlitelimab in Adults With Nonresponsive Celiac Disease
Status: NOT_YET_RECRUITING
Conditions: Coeliac Disease
Interventions: DRUG: Amlitelimab|DRUG: Placebo|DIETARY_SUPPLEMENT: SIGE|DIETARY_SUPPLEMENT: Gluten-free product (GFP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-protein Quantity and Quality RUTF in Improving Linear Growth Among Children With Severe Wasting
Status: COMPLETED
Conditions: Severe Wasting|Severe Acute Malnutrition
Interventions: DIETARY_SUPPLEMENT: High-protein RUTF|DIETARY_SUPPLEMENT: Standard RUTF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modified CD19 CAR-T in Patients With Relapsed or Refractory CD19+ B-cell Malignancies
Status: UNKNOWN
Conditions: Refractory B-Cell Non-Hodgkin Lymphoma|Refractory Leukemia
Interventions: BIOLOGICAL: Modified anti-CD19 CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Attenuation of Post-infarct LV Remodeling by Mechanical Unloading Using Impella-CP
Status: UNKNOWN
Conditions: Myocardial Infarction|Remodeling, Ventricular|Shock, Cardiogenic
Interventions: PROCEDURE: LV mechanical unloading by Impella-CP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2b Study of DU-176b, Prevention of Venous Thromboembolism in Patients After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Venous Thromboembolism|Deep Vein Thrombosis|Total Knee Arthroplasty
Interventions: DRUG: DU-176b|DRUG: DU-176b|DRUG: DU-176b|DRUG: DU-176b|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Efficacy of Fecal Microbiota Transplantation(FMT) in the Treatment of Depression
Status: NOT_YET_RECRUITING
Conditions: Depression
Interventions: DRUG: Fecal microbiota transplantation(FMT)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of TPIAT for Resectable Adenocarcinoma of the Pancreas Region at High Risk of Postoperative Fistula
Status: RECRUITING
Conditions: Adenocarcinoma of the Pancreas|Adenocarcinoma of the Duodenum|Ampullary Adenocarcinoma
Interventions: PROCEDURE: total pancreatectomy|BIOLOGICAL: intraportal islet autotransplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyaluronic Acid vs Platelet Rich Plasma: Effects on Clinical Outcomes and Intra-articular Biology for the Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: Platelet-rich Plasma (PRP)|BIOLOGICAL: Hyaluronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypercapnia and Gas Exchange Under the Avalanche Snow Model (HyperAvaSM)
Status: COMPLETED
Conditions: Accident Caused by Snow Avalanche
Interventions: OTHER: Breathing in the simulated avalanche snow.|DEVICE: air pocket
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Analgesic Effect Between Intrathecal Morphine and IV-fentanyl Patient Controlled Analgesia (ITM-IVPCA) and Epidural PCA (PCEA) in Patients Undergoing Gastrectomy -Randomized Allocation Study-
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: morphine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GPS (Giving Parents Support): Parent Navigation After NICU Discharge
Status: COMPLETED
Conditions: Premature Birth of Newborn|Family|Immature Newborn|Newborn Morbidity|Infant Newborn Disease
Interventions: BEHAVIORAL: Parent Navigator|BEHAVIORAL: Care Notebook
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Therapeutic Effects of Statins and Fibrates on Unstable Atherosclerotic Plaques
Status: WITHDRAWN
Conditions: Atherosclerosis
Interventions: DRUG: Atorvastatin|DRUG: Gemfibrozil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Two Simeticone Brands in Adults With Functional Dyspepsia
Status: COMPLETED
Conditions: Functional Dyspepsia
Interventions: DRUG: Imonogas|DRUG: Espumisan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: G-CSF in Preventing Neutropenia in Patients With Solid Tumors Who Are Receiving Chemotherapy
Status: COMPLETED
Conditions: Chemotherapeutic Agent Toxicity|Neutropenia|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Adding Computerized Executive Training on Balance, Motor Symptoms and Gait in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: REHACOM Software|OTHER: Designed Physical Therapy Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Hyponatremia in Preterm Infants on Diuretics
Status: TERMINATED
Conditions: Bronchopulmonary Dysplasia|Hyponatremia on Diuretics
Interventions: PROCEDURE: Sodium supplementation|PROCEDURE: Fluid restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Effectiveness of Oral Sucrolfate, Alginate and Hydrotalcide in Dispeptic Pain Treatment
Status: COMPLETED
Conditions: Dyspepsia
Interventions: DRUG: Alginate|DRUG: Sucralfate|DRUG: Hydrotalcite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Eltrombopag With or Without Hypomethylating Agent After Hypomethylating Agent Failure For Patients With Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Eltrombopag|DRUG: Hypomethylating Agent (HMA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation in Kidney Stone Patients
Status: NOT_YET_RECRUITING
Conditions: Kidney Stones
Interventions: DRUG: Microbial Transplant Therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparative Effects of Nebivolol and Metoprolol on Female Sexual Function
Status: COMPLETED
Conditions: Hypertension|Female Sexual Dysfunction
Interventions: DRUG: nebivolol and metoprolol succinate|DRUG: metoprolol succinate and nebivolol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Time-restricted Feeding as a Dietary Strategy Against Metabolic Disturbances in Humans
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Early Time-Restricted Feeding|BEHAVIORAL: Late Time-Restricted Feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Triple-Blind Placebo-Controlled Study to Evaluate the Effects of a Supplement on Lower Urinary Tract Symptoms in Men.
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms|Benign Prostatic Hyperplasia|Erectile Dysfunction
Interventions: DIETARY_SUPPLEMENT: ProstaThrive™ Supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hearing Results and Post Surgical Outcomes Using Amniotic Membrane Allograft vs. Fascia for Tympanoplasty
Status: WITHDRAWN
Conditions: Tympanic Membrane Perforation
Interventions: OTHER: Skye Barrier|OTHER: Fascia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Criteria for Liver Transplantation in Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Liver Cancer|Advanced Adult Hepatocellular Carcinoma|Cirrhosis, Liver|Unresectable Liver Cancer|Liver Transplant Disorder
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anti-inflammatory Effect of Curcumin, Homotaurine, Vitamin D3 on Human Vitreous in Patients With Diabetic Retinopathy
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: OTHER: curcumin, homotaurine, vitamin D3|OTHER: control
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: carDIo-ttranSSfOrm nucLEar Imaging Study
Status: RECRUITING
Conditions: Amyloidosis|Transthyretin Amyloid Cardiomyopathy
Interventions: DIAGNOSTIC_TEST: 99m-technetium pyrophosphate scintigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: TECH App Marijuana Use Intervention for Court-Involved Adolescents
Status: RECRUITING
Conditions: Cannabis Use|Adolescent
Interventions: BEHAVIORAL: Treatment as usual|BEHAVIORAL: Teen Empowerment through Computerized Health (TECH) app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Metformin HCl 750 mg ER Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Metformin HCl 750 mg Extender Release tablets, single dose|DRUG: GLUCOPHAGE® XR 750 mg tablets, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Hydroxychloroquine in Isolated Cutaneous Mastocytosis Patients or Indolent Systemic Mastocytosis With Associated Skin Involvement Patients
Status: UNKNOWN
Conditions: Mastocytosis
Interventions: DRUG: Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sonoelastography: Ultrasound Method to Measure Liver Fibrosis
Status: COMPLETED
Conditions: Chronic Liver Disease|Non-Alcoholic Fatty Liver Disease|Hepatitis C Virus (HCV) Coinfection|Hepatitis B Virus (HBV)|Drug-Induced Liver Injury
Interventions: DEVICE: Shear Wave Sonoelastography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Adding Lidocaine 10% to Phenol in Ultrasound Guided Superior Hypogastric Plexus Neurolysis in The Management of Pelvic Cancer Pain
Status: UNKNOWN
Conditions: Efficacy of Adding Lidocaine 10% to Phenol in Superior Hypogastric Plexus Neurolysis
Interventions: OTHER: Ultrasound Guided Superior Hypogastric Plexus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigation Into the Pathophysiology and Treatment of Varicose Veins
Status: COMPLETED
Conditions: Varicose Veins
Interventions: PROCEDURE: Chemical sclerotherapy|DRUG: 1% Sodium Tetradecyl Sulphate|DRUG: 3% Sodium Tetradecyl Sulphate|DRUG: 0.5% Polidocanol|DRUG: 3% Polidcanol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Se-Methyl-Seleno-L- Cysteine (MSC) in Treating Healthy Patients
Status: COMPLETED
Conditions: Healthy, no Evidence of Disease
Interventions: DRUG: Se-methyl-seleno-L-cysteine|OTHER: placebo|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Positronic Emission Tomography (PET) Imaging in Post Radiation Evaluation of Head and Neck Tumours (PET PREVENT Trial)
Status: COMPLETED
Conditions: Cancer of the Head and Neck
Interventions: OTHER: PET scan in addition to conventional CT imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: In-vivo Wear Behaviour of AS Coated Versus Uncoated Columbus® Total Knee Prosthesis
Status: RECRUITING
Conditions: Knee Arthritis|Knee Osteoarthritis|Primary Osteoarthritis of Knee Nos|Secondary Osteoarthritis of Knee Nos|Rheumatoid Arthritis of Knee|Instability, Joint|Osteonecrosis|Deformity Knee
Interventions: DEVICE: total knee prosthesis implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Different Preoperative Fasting Times in Pediatric Patients Undergoing Elective General Anaesthesia
Status: COMPLETED
Conditions: Pulmonary Aspiration of Gastric Contents
Interventions: PROCEDURE: Nasogastric aspiration for measurement of Residual Gastric Volume|PROCEDURE: Nasogastric Aspiration for Measurement of Gastric pH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Validation of Multidimensional Assessment of THYmic States (MATHYS): A Study in a Population of Bipolar Patients Treated With Olanzapine
Status: COMPLETED
Conditions: Bipolar Disorder I or II
Interventions: DRUG: olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluconazole Versus Micafungin for Candida Bloodstream Infection in Non-Neutropenic Patients
Status: WITHDRAWN
Conditions: Candidiasis|Sepsis
Interventions: DRUG: Fluconazole|DRUG: Micafungin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Trial Evaluates the Efficacy, Immunogenicity and Safety Profile of HPV Vaccine
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Papillomavirus Infection
Interventions: BIOLOGICAL: Recombinant Nonavalent (types 6/11/16/18/31/33/45/52/58) Human Papillomavirus (HPV) Vaccine (Escherichia coli)|BIOLOGICAL: Recombinant Quadrivalent Human Papillomavirus (Types 6,11,16,18) Vaccine (Saccharomyces cerevisiae)（GARDASIL®）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Compare the Pharmacokinetics (PK) of GSK2982772 Following Administration of Different Modified Release (MR) Formulations in Capsule and MR Tablet Formulations Relative to an Immediate Release (IR) Tablet Formulation and to Check the PK of MR Formulation in Capsule Following Repeat Doses
Status: COMPLETED
Conditions: Autoimmune Diseases
Interventions: DRUG: GSK2982772 Modified Release|DRUG: GSK2982772 Immediate Release
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Cervical Ultrasound and Echoscintigraphy for Preoperative Localization Diagnosis in Primary Hyperparathyroidism
Status: UNKNOWN
Conditions: Primary Hyperparathyroidism
Interventions: OTHER: cervical ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Microfragmented Adipose Tissue Compared to Corticosteroid Injection for the Treatment of Knee Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Osteoarthritis|Osteo Arthritis Knee
Interventions: DEVICE: Microfragmented Adipose Tissue|DRUG: Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Vitamin D Supplementation on Aerobic Fitness in Athletes
Status: COMPLETED
Conditions: Aerobic Fitness (VO2max)
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Study of Fecal Microbiota Transplantation in the Treatment of Antibiotic-associated Diarrhea
Status: COMPLETED
Conditions: Fecal Microbiota Transplantation|Antibiotic-associated Diarrhea
Interventions: PROCEDURE: Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antisense Oligonucleotide Treatment for PCARP Disease Due to Mutation in FLVCR1
Status: ENROLLING_BY_INVITATION
Conditions: Posterior Column Ataxia With Retinitis Pigmentosa
Interventions: DRUG: nL-FLVC-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Water for Reducing Pain in Negative Pressure Wound Therapy
Status: COMPLETED
Conditions: Treatment
Interventions: PROCEDURE: NPWT with cold water|PROCEDURE: NPWT with normal saline room temp|PROCEDURE: NPWT without other intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Circulatory Management and Acute Kidney Injury in Patients Undergoing Partial Nephrectomy
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: OTHER: Goal-directed circulatory management|OTHER: Routine circulatory management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: MUK Nine b: OPTIMUM Treatment Protocol
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Cyclophosphamide|DRUG: Bortezomib|DRUG: Lenalidomide|DRUG: Daratumumab|DRUG: Dexamethasone|DRUG: Melphalan|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of SinoFresh Nasal and Sinus Care Nasal Spray in Eliminating MRSA From the Nasal Cavity
Status: WITHDRAWN
Conditions: MRSA Infection
Interventions: DRUG: Sinofresh|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT