pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Manual Therapy and Kinesio Taping on Temporomandibular Joint Dysfunction Following Oral Surgeries
Status: COMPLETED
Conditions: Temporomandibular Joint Dysfunction
Interventions: DEVICE: Kinesio tape|OTHER: Gauze pack|DEVICE: ice pack|PROCEDURE: Manual therapy|DRUG: Analgesic|DRUG: Proteolytic enzymes|DRUG: Mouth wash|DIETARY_SUPPLEMENT: Soft cold diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genetic Biomarkers in Saliva Samples From Patients With Ewing Sarcoma
Status: COMPLETED
Conditions: Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor (PNET)
Interventions: OTHER: laboratory biomarker analysis|OTHER: questionnaire administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Standard Surgery or Minimal-Access Surgery in Treating Patients With Bladder Cancer
Status: UNKNOWN
Conditions: Bladder Cancer
Interventions: OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment|PROCEDURE: robot-assisted laparoscopic surgery|PROCEDURE: therapeutic conventional surgery|PROCEDURE: therapeutic laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BrUOG 397: NEO Rad (LOW): Neoadjuvant Low Dose Stereotactic Body Radiotherapy, Ipilimumab and Nivolumab
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Ipilimumab|DRUG: Nivolumab|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STrategies for Anticoagulation in Patients With thRombocytopenia and Cancer-associated Thrombosis
Status: RECRUITING
Conditions: Cancer-associated Thrombosis|Thrombocytopenia
Interventions: BIOLOGICAL: Enoxaparin|BIOLOGICAL: Dalteparin|BIOLOGICAL: Tinzaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Safety and Efficacy of DBI-001 Gel, DBI-002 Gel, and Aqueous Gel in Subjects With Onychomycosis
Status: SUSPENDED
Conditions: Onychomycosis
Interventions: BIOLOGICAL: DBI-001|BIOLOGICAL: DBI-002|BIOLOGICAL: Aqueous Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of CTX-712 in Relapsed/Refractory Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: CTX-712
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Check the Safety and Effectiveness of Botanical Extract Standardized for Iron + Vitamin c and Botanical Extract Standardized for Iron in Adult Human Subjects With Anemia or Iron-deficiency Anemia
Status: NOT_YET_RECRUITING
Conditions: Anemia, Iron Deficiency
Interventions: DIETARY_SUPPLEMENT: placebo|DIETARY_SUPPLEMENT: Botanical Extract Standardized for Iron + Vitamin C|DIETARY_SUPPLEMENT: Botanical Extract Standardised for Iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PT003 MDI Cardiovascular Safety Study
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: PT005 MDI|DRUG: PT001 MDI|DRUG: PT003 MDI|DRUG: Formoterol Fumarate 12 μg (Foradil® Aerolizer®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Research Study to Assess the Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and Gingivitis.
Status: ACTIVE_NOT_RECRUITING
Conditions: Gingivitis|Plaque
Interventions: DRUG: manual Tooth Brush + Colgate Total TP (0.454% SnF, 1100 ppm F)|DRUG: manual toothbrush + Colgate dental cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2b Study of UGN-102 for Low Grade Intermediate Risk Non-Muscle-Invasive Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer|Urothelial Carcinoma|Urothelial Carcinoma Bladder
Interventions: DRUG: UGN-102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Vildagliptin in Combination With Pioglitazone in Drug Naive Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Single-center, Open-label, Pilot Study to Compare the Effectiveness and Safety of Diuretics Add-On Strategy in Chronic Heart Failure Patients (DIOS 1)
Status: WITHDRAWN
Conditions: Congestive Heart Failure
Interventions: DRUG: furosemide/no spironolactone|DRUG: metolazone/no spironolactone|DRUG: furosemid/spironolactone|DRUG: metolazone/spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spread and Scale of a Polypharmacy App
Status: UNKNOWN
Conditions: Polypharmacy|Deprescribing|Adverse Drug Event
Interventions: OTHER: MedReviewRx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Buccal Plate Expansion Technique Versus Guided Bone Regeneration Technique in Socket Preservation in the Aesthetic Zone.
Status: UNKNOWN
Conditions: Bone Resorption After Tooth Extraction
Interventions: PROCEDURE: Buccal plate expansion technique for dental socket preservation|PROCEDURE: Guided bone regeneration technique for post-extraction dental socket preservation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Ipomea Pes-caprae Ointment as an add-on Therapy in Patient With Jellyfish Dermatitis
Status: COMPLETED
Conditions: Jellyfish Dermatitis|Jellyfish Venoms
Interventions: DRUG: Ipomea pes-caprae ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Adolescent Idiopathic Scoliosis
Interventions: DEVICE: MID-C System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Savolitinib Combine With Durvalumab in EGFR Wild-type Locally Advanced or Metastatic NSCLC
Status: SUSPENDED
Conditions: Lung Cancer
Interventions: DRUG: Savolitinib|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Demonstrate the Therapeutic Clinical Equivalence of Two Mometasone Nasal Sprays
Status: UNKNOWN
Conditions: Nasal Obstruction|Sneezing|Itching
Interventions: DRUG: Mometasone furoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effect of Pulsed Magnetic Therapy Versus Phonophoresis in Discogenic Lumbar Radiculopathy Patients
Status: NOT_YET_RECRUITING
Conditions: Lumbar Radiculopathy
Interventions: OTHER: Pulsed electromagnetic therapy|OTHER: Ultrasound phonophoresis|OTHER: Conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Early Use of Rosuvastatin in Acute Coronary Syndromes: Targeting Platelet-Leukocyte Interactions
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Angioplasty, Transluminal, Percutaneous Coronary|Hydroxymethylglutaryl-CoA Reductase Inhibitors|Blood Platelets
Interventions: DRUG: rosuvastatin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of GX-188E DNA Therapeutic Vaccine Administered by Electroporation to Cervical Intraepithelial Neoplasia Grade 3
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia 3
Interventions: GENETIC: GX-188E administered by electroporation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AV Node Ablation and Pacemaker Therapy Compared to Drug Therapy for Atrial Fibrillation - Pilot Study
Status: TERMINATED
Conditions: Atrial Fibrillation|Heart Failure
Interventions: DRUG: FDA approved rate and rhythm control drugs|DEVICE: AV Node ablation and device implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cystatin SN Binds to Phytic Acid and Predicts Non-heme Iron Bioavailability
Status: COMPLETED
Conditions: Iron-deficiency|Iron Deficiency Anemia
Interventions: DIETARY_SUPPLEMENT: phytic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Remote Ischaemic Preconditioning for Heart Surgery (RIPHeart-Study)
Status: TERMINATED
Conditions: Myocardial Injury|Mortality
Interventions: PROCEDURE: Remote Ischemic Preconditioning|PROCEDURE: Control/sham procedure (blood pressure cuff)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Extraction-site, - Midline Incision vs Off-midline Incision-
Status: UNKNOWN
Conditions: Colon Cancer
Interventions: OTHER: midline incision or off-midline incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Project Insight: Feasibility of a Breast Cancer Screening Decision Support Tool
Status: COMPLETED
Conditions: Breast Cancer Screening|Oncology|Preventative Medicine|Mammography
Interventions: OTHER: Breast Cancer Screening Decision Support Tool|OTHER: National Cancer Institute Breast Cancer Screening PDQ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ocular Pathogen and Transcriptome Investigation Using Comprehensive Sequencing
Status: RECRUITING
Conditions: Uveitis|Infectious Disease
Interventions: DEVICE: Metagenomic Deep Sequencing (MDS)|DIAGNOSTIC_TEST: Standard of Care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Blinatumomab, Inotuzumab Ozogamicin, and Combination Chemotherapy as Frontline Therapy in Treating Patients With B Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: B Acute Lymphoblastic Leukemia|B Lymphoblastic Lymphoma
Interventions: BIOLOGICAL: Blinatumomab|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Dexamethasone|DRUG: Doxorubicin Hydrochloride|BIOLOGICAL: Inotuzumab Ozogamicin|OTHER: Laboratory Biomarker Analysis|DRUG: Mercaptopurine|DRUG: Methotrexate|BIOLOGICAL: Ofatumumab|DRUG: Prednisone|BIOLOGICAL: Rituximab|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effect of Nutritional Supplementation on Growth of Short and Lean Adolescents Boys
Status: COMPLETED
Conditions: Growth Problem|Low Weight|Short Stature
Interventions: DIETARY_SUPPLEMENT: Nutritional supplementation standardized formula|DIETARY_SUPPLEMENT: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multidetector Computed Tomography (MDCT) Evaluation of Obstructive Jaundice: A Cross-sectional Study From a Tertiary Hospital of Nepal
Status: COMPLETED
Conditions: Obstuctive Jaundice|Radiological Correlation of Obstructive Jaundice
Interventions: RADIATION: CT Scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Viral Load Analysis of the SARS-CoV-2 Virus in Nose Versus Mouth Sites
Status: ACTIVE_NOT_RECRUITING
Conditions: Sars-CoV-2 Infection
Interventions: DIAGNOSTIC_TEST: Nasal and mouth swab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Investigate the Effect of Formulation, Food, and Rabeprazole on the Pharmacokinetics (PK) of GDC-0853 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: GDC-0853|DRUG: Rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Fampridine on Working Memory in Healthy Subjects
Status: WITHDRAWN
Conditions: Working Memory
Interventions: DRUG: Fampridine SR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neuromodulation in the Elderly Depressed: a Brain Imaging Pilot Study
Status: RECRUITING
Conditions: Old Age|Depressive Disorder, Treatment-Resistant
Interventions: DEVICE: a Magstim Rapid2 Plus1 Magnetic Stimulator connected to a Brainsway H1 coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Canadian Study of the MicroVention Flow Re-Direction (FRED) Endoluminal Device Stent System in the Treatment of Intracranial Aneurysms
Status: WITHDRAWN
Conditions: Intracranial Aneurysms
Interventions: DEVICE: FRED
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Myofascial Pain Syndrome Treatment in Patients With Cancer in Palliative Care
Status: COMPLETED
Conditions: Myofascial Pain Syndromes|Cancer
Interventions: COMBINATION_PRODUCT: 1% lidocaine injection in trigger points
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Four and Eight Hours Dialysis Sessions in Thrice Weekly Hemodialysis
Status: COMPLETED
Conditions: End-Stage Renal Disease|Hemodialysis
Interventions: PROCEDURE: 4-hour thrice weekly in center hemodialysis|PROCEDURE: 8-hour thrice weekly in center hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anesthesia Depth Increases Delirium Incidence
Status: COMPLETED
Conditions: Delirium|Anesthesia Awareness
Interventions: DEVICE: BIS guidance of anesthesia|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness and Adherence of Modified Alternate-day Calorie Restriction (MACR) in Non-Alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: BEHAVIORAL: Calorie restriction (MACR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Clinical Study of MR13A9 in Hemodialysis Patients With Pruritus.
Status: COMPLETED
Conditions: Uremic Pruritus
Interventions: DRUG: MR13A9|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lisocabtagene Maraleucel (JCAR017) as Second-Line Therapy (TRANSCEND-PILOT-017006)
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|Lymphoma, Nonhodgkin|Lymphoma, B-Cell|Lymphoma, Large B-Cell, Diffuse
Interventions: BIOLOGICAL: lisocabtagene maraleucel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Child HCAHPS: Automated Day of Discharge Survey
Status: TERMINATED
Conditions: Inpatient Experience Survey Administration|Inpatient Experience Survey Response
Interventions: OTHER: Child HCAHPS: Automated day-of-discharge survey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Formal Letter of Invitation on Male Partner Involvement at Antenatal Care Clinic
Status: COMPLETED
Conditions: Male Reproductive Problem
Interventions: BEHAVIORAL: letter of invitation on MI in PMTCT service
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Implementing an Effective Diabetes Intervention Among Low-Income Immigrants
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Diabetes Self-Management Education and Support (DSMES) Videos|BEHAVIORAL: Community Health Worker Support (CHW)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: qQ-lab Daily-IBS for Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome (IBS)
Interventions: DIETARY_SUPPLEMENT: gQ-lab daily|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of SPSIPB on Postoperative Pain and Analgesic Consumption in Patients Undergoing VATS
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: OTHER: Serratus posterior superior intercostal plane block (SPSIPB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Tolerability and Efficacy of Rosuvastatin - Fenofibrate Combine Therapy in Korean Patients With Combined Hyperlipidemia
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: Lipid modification|DRUG: Lipid modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual Boosted Protease Inhibitor Regimens Without Any Additional Antiretroviral Therapy in HIV-1 Infected Patients (ANRS127)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Fosamprenavir|DRUG: Saquinavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fulvestrant in Treating Patients With Recurrent, Persistent, or Metastatic Endometrial Cancer
Status: UNKNOWN
Conditions: Recurrent Uterine Corpus Carcinoma|Stage III Uterine Corpus Cancer AJCC v7|Stage IV Uterine Corpus Cancer AJCC v7
Interventions: DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peer-Delivered Episodic Future Thinking for Returning Citizens
Status: RECRUITING
Conditions: Behavior, Health
Interventions: BEHAVIORAL: Elongating Time HOrizons for Reentry (ETHoR)|BEHAVIORAL: Standardized Episodic Thinking (SET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Omalizumab in Patients With Moderate to Severe Persistent Allergic Asthma Not Adequately Controlled Despite GINA (2009) Step 4 Therapy
Status: COMPLETED
Conditions: Persistent Allergic Asthma
Interventions: DRUG: Omalizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Inertial Sensors vs the Conventional Technique for the Execution of the Bone Resections in Primary TKA
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Total knee replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Navitoclax and Vistusertib in Treating Patients With Relapsed Small Cell Lung Cancer and Other Solid Tumors
Status: TERMINATED
Conditions: Metastatic Malignant Solid Neoplasm|Recurrent Lung Small Cell Carcinoma|Recurrent Malignant Solid Neoplasm|Refractory Malignant Solid Neoplasm|Stage III Lung Small Cell Carcinoma, by American Joint Committee on Cancer (AJCC) v7|Stage IIIA Lung Small Cell Carcinoma AJCC v7|Stage IIIB Lung Small Cell Carcinoma AJCC v7|Stage IV Lung Small Cell Carcinoma AJCC v7|Unresectable Solid Neoplasm
Interventions: BIOLOGICAL: Navitoclax|DRUG: Vistusertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety, Tolerability, and Pharmacokinetics of Lanadelumab Administered Intravenously in Healthy Adult Volunteer Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Lanadelumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Followed by FEC Versus Paclitaxel and RAD001 Followed by FEC In Women With Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: 5-Fluorouracil|DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: RAD001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Double Blinded Placebo-Controlled w/Semaglutide to Prevent Weight Gain After Liver Transplant
Status: RECRUITING
Conditions: NAFLD
Interventions: DRUG: Semaglutide Pen Injector|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 3M Oral Rinse Incidence and Patient Acceptance of Sloughing When Used With Sodium Lauryl Sulfate (SLS) Toothpastes
Status: TERMINATED
Conditions: Oral Mucosal Disorder
Interventions: DRUG: No SLS toothpaste|DRUG: Medium SLS toothpaste|DRUG: High SLS toothpaste|DEVICE: Anti-plaque
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Metformin/Rosuvastatin Combination Therapy With in Patients With Type 2 Diabetes and Dyslipidemia
Status: COMPLETED
Conditions: Type 2 Diabetes|Dyslipidemia
Interventions: DRUG: Metformin + Rosuvastatin|DRUG: Metformin + placebo|DRUG: placebo + Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Electroacupuncture Versus Solifenacin Succinate for Female Overactive Bladder
Status: RECRUITING
Conditions: Overactive Bladder
Interventions: DEVICE: electroacupuncture|DRUG: Solifenacin Succinate Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-density Activation Mapping of the Slow Pathwayto Guide Catheter Ablation in Patients With Typical Atrioventricular Nodal Reentrant Tachycardia
Status: COMPLETED
Conditions: Supraventricular Tachycardia|Atrioventricular Nodal Re Entrant Tachycardia
Interventions: DEVICE: Description of Slow pathway signals to facilitate ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effects of TRV130, at Therapeutic and Supra Therapeutic Doses, on QTc Intervals
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TRV130|DRUG: Moxifloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Leadership, Engagement, and Youth Activism Program With Mindfulness (LEAP)
Status: RECRUITING
Conditions: Adolescent Behavior|Mental Health Wellness 1
Interventions: BEHAVIORAL: Leadership, Engagement, and youth Activism Program with Mindfulness|BEHAVIORAL: EnvisionIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fludeoxyglucose F 18-PET/CT Scans in Patients Receiving Ultra Short-Term Dexamethasone For Lung Nodules
Status: COMPLETED
Conditions: Pulmonary Nodule
Interventions: DRUG: dexamethasone|PROCEDURE: PET/Computed Tomography (CT)|RADIATION: fludeoxyglucose (18F)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase I/II Trial of Antagonism of HER in GI Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer|Recurrent Colorectal Cancer
Interventions: DRUG: AZD8931|DRUG: Irinotecan|DRUG: Folinic Acid|DRUG: Fluorouracil|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of NHF and Nebulizer on Lung Function in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Nasal high flow (NHF)|DEVICE: Nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Pharmacokinetics of MK-7145 Following Single Dose Administration in Participants With Moderate Renal Insufficiency (MK-7145-018)
Status: WITHDRAWN
Conditions: Renal Insufficiency
Interventions: DRUG: MK-7145
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Revaccination With Subunit Influenza A/Vietnam/1203/2004 (H5N1) Vaccine
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza A/Vietnam/1203/2004 (H5N1; sanofi pasteur)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ketamine in Colorectal Surgery
Status: WITHDRAWN
Conditions: Acute Pain|Pain, Postoperative|Colorectal Surgery
Interventions: DRUG: Placebo|DRUG: Ketamine|DRUG: Acetaminophen|DRUG: Opioid|DRUG: Alvimopan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Safety and Efficacy of the dTMS Treatment for OCD
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: DEVICE: Active DTMS Treatment|DEVICE: Sham Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of New Computer-based Neuropsychological Tool: Visual Tests, Touch Responses
Status: RECRUITING
Conditions: Cerebral Neurological Illness
Interventions: DIAGNOSTIC_TEST: Railroad Test|DIAGNOSTIC_TEST: Swamp Test|DIAGNOSTIC_TEST: Presidents Recognition Test|DIAGNOSTIC_TEST: Judgment of Line Orientation|DIAGNOSTIC_TEST: Symbol Span subtest of the Wechsler Memory Scale-IV|DIAGNOSTIC_TEST: Information subtest of the Wechsler Adult Intelligence Scale-IV:|DIAGNOSTIC_TEST: Digit Span subtest of the Wechsler Adult Intelligence Scale-I|DIAGNOSTIC_TEST: Reading subtest of the Wide Range Achievement Test|DIAGNOSTIC_TEST: Symbol Digit Modalities Test:|DIAGNOSTIC_TEST: Dot Counting Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Continuous Norepinephrine Administration and Blood Pressure Stability During Anesthetic Induction
Status: COMPLETED
Conditions: Blood Pressure|Perioperative Hypotension
Interventions: OTHER: Continuous norepinephrine infusion via an infusion pump|OTHER: Manual bolus norepinephrine administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of Duvelisib in Participants With Refractory Indolent Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Indolent Non-Hodgkin Lymphoma
Interventions: DRUG: Duvelisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ambroxol as a Disease-modifying Treatment in GBA-PD
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease|GBA Gene Mutation
Interventions: DRUG: Ambroxol Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ivermectin Treatment of Persons With Onchocerciasis-associated Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: ivermectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Effects of Dibifree® on Regulation of Blood Sugar and HbA1c in Patients With Type II Diabetes
Status: COMPLETED
Conditions: Type II Diabetes
Interventions: DIETARY_SUPPLEMENT: Compound plant extracts|DIETARY_SUPPLEMENT: Indigestible dextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Pemetrexed, Carboplatin, and Bevacizumab as First-Line Therapy in Treating Older Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: carboplatin|DRUG: pemetrexed disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Neoadjuvant Chemotherapy Combined With Bevacizumab for Locally Advanced Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: PROCEDURE: FOLFIRI+beacizumab|PROCEDURE: CRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Natural Extract on the Post-prandial Blood Glucose Response After Bread Consumption: a Dose-response of Efficacy
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: no added fruit extract|DIETARY_SUPPLEMENT: fruit extract|DIETARY_SUPPLEMENT: fruit extract|DIETARY_SUPPLEMENT: fruit extract|DIETARY_SUPPLEMENT: fruit extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Investigational Scan (89Zr-DFO-GmAb PET/CT) Compared to Contrast-Enhanced CT for the Detection of Recurrent Clear Cell Renal Cell Cancer After Surgery Comparing Carbonic Anhydrase IX (CAIX) PET CT to Conventional PET CT for Post-Op Staging in Kidney Cancer
Status: RECRUITING
Conditions: Clear Cell Renal Cell Carcinoma|Sarcomatoid Renal Cell Carcinoma|Stage II Renal Cell Cancer|Stage III Renal Cell Cancer|Stage IV Renal Cell Cancer
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|OTHER: Questionnaire Administration|DRUG: Zirconium Zr 89 Girentuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: New Pre-Surgical Scoring System for Uterine Septum
Status: RECRUITING
Conditions: Septate Uterus
Interventions: DIAGNOSTIC_TEST: Shawki Septum Scoring System|DIAGNOSTIC_TEST: ESHRE ASRM Classification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Initiation of ARNi and SGLT2i in Patients With HFrEF
Status: RECRUITING
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: DRUG: Sacubitril-valsartan|DRUG: SGLT2 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Staying Active With Arthritis: RCT of Physical Activity for Older Adults With Osteoarthritis and Hypertension
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Hypertension
Interventions: BEHAVIORAL: STAR Intervention|BEHAVIORAL: Attention-Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assisting Smokers to Switch to an e-Cigarette by Accelerating Learning of Adaptive Habits Using D-cycloserine
Status: RECRUITING
Conditions: Smoking Cessation|Harm Reduction
Interventions: DRUG: d-cycloserine|OTHER: Juul e-cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VRC 313: A Trivalent Virus-like Particle (VLP) Encephalitis Vaccine (WEVEE) in Healthy Adults
Status: COMPLETED
Conditions: Venezuelan Equine Encephalitis|Western Equine Encephalitis|Eastern Equine Encephalitis|Alphavirus Infections
Interventions: BIOLOGICAL: VRC-WEVVLP073-00-VP|OTHER: VRC-GENMIX083-AL-VP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Use of Endotracheal Tube With Subglottic Suction in Rhinoplasty
Status: COMPLETED
Conditions: Rhinoplasty
Interventions: OTHER: Suction Above Cuff Endotracheal Tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Clinical Study for Evaluating The Safety And Efficacy Of Epodion®
Status: COMPLETED
Conditions: Chronic Kidney Disease (CKD)
Interventions: BIOLOGICAL: Recombinant Human Erythropoietin Alpha|BIOLOGICAL: Recombinant Human Erythropoietin Alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Skill-Based HIV Psychoeducation in IV-Drug Abuser for Reducing High-risk Behavior
Status: COMPLETED
Conditions: Addiction|Risk Reduction Behaviour
Interventions: BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Medications for Obstructive Sleep Apnea to Improve Cognition in Children With Down Syndrome
Status: RECRUITING
Conditions: Obstructive Sleep Apnea|Down Syndrome
Interventions: DRUG: Atomoxetine and Oxybutynin (ato-oxy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo-controlled Trial of F-627 in Women With Breast Cancer Receiving Myelotoxic Chemotherapy
Status: COMPLETED
Conditions: Breast Cancer|Neutropenia
Interventions: DRUG: F-627|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study, Prospective, of Volume, Composition and Bacteriology of the Recovered Blood of Multi-perforated Catheter Inserted in the Drapes Thickness of Incisional Sternal Area During Heart Surgery
Status: COMPLETED
Conditions: Heart Surgery
Interventions: PROCEDURE: heart surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of High Impact Exercise on Bone and Articular Cartilage in Post-menopausal Women
Status: UNKNOWN
Conditions: Osteoporosis, Postmenopausal|Osteoarthritis, Knee|BMD
Interventions: BEHAVIORAL: Hopping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of SMART101 in Pediatric and Adult Patients With Hematological Malignancies After T Cell Depleted Allo-HSCT
Status: RECRUITING
Conditions: Hematological Malignancies
Interventions: BIOLOGICAL: Allogeneic T cell progenitors, cultured ex-vivo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Interferon Gamma-1b in Hepatitis C Patients With Liver Fibrosis or Cirrhosis
Status: COMPLETED
Conditions: Liver Fibrosis|Cirrhosis
Interventions: DRUG: interferon gamma-1b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Different Dosages' Ge Gen Qin Lian Decoction in the Treatment of Type 2 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Dose-Response Relationship, Drug
Interventions: DRUG: High Dose GGQL Decoction|DRUG: Mild dose GGQL Decoction|DRUG: Low dose GGQL Decoction|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Nanocort in Acute Exacerbation of Relapsing-Remitting Multiple Sclerosis (MS)
Status: TERMINATED
Conditions: Acute Exacerbation of Remitting Relapsing Multiple Sclerosis|Clinically Isolated Syndrome
Interventions: DRUG: PEG-liposomal prednisolone sodium phosphate|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Effects of High Load Strength Training With and Without Tissue Specific Planter Facia Stretching With Planter Fasciitis
Status: RECRUITING
Conditions: Plantar Fascitis|Resistance Training|Muscle Stretching Exercises
Interventions: OTHER: high load strength training and Tissue-specific plantar fascia stretching exercise for 12 weeks|OTHER: high-load strength training with routine physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Chordate System S020 Acute Migraine Clinical Investigation
Status: TERMINATED
Conditions: Acute Migraine
Interventions: DEVICE: Chordate System S020 in treatment mode|DEVICE: Chordate System S020 in placebo mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of High Frequency Percussive Ventilation on Cerebral Tissue Oxygenation
Status: UNKNOWN
Conditions: Patients at the Intensive Care Unit (ICU)
Interventions: DEVICE: Near-Infrared Spectroscopy (NIRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Immunogenicity of Trivalent Split Influenza Vaccine Using the Strain Composition 2007/2008
Status: COMPLETED
Conditions: Seasonal Influenza|Vaccine
Interventions: BIOLOGICAL: trivalent split influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Efficacy and Safety of GP681 Versus Placebo for Postexposure Prophylaxis Against Influenza
Status: NOT_YET_RECRUITING
Conditions: Influenza
Interventions: DRUG: GP681 40mg|DRUG: GP681 Simulant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of CC-95251, a Monoclonal Antibody Directed Against SIRPα, in Participants With Advanced Solid and Hematologic Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoplasms
Interventions: DRUG: CC-95251|DRUG: Rituximab|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigational Scan (68Ga-FAPI-46 PET/CT) for the Imaging of Cancer-Associated Fibroblasts in Patients With Localized Pancreatic Ductal Adenocarcinoma
Status: RECRUITING
Conditions: Localized Pancreatic Adenocarcinoma|Resectable Pancreatic Ductal Adenocarcinoma|Stage 0 Pancreatic Cancer AJCC v8|Stage I Pancreatic Cancer AJCC v8|Stage IIA Pancreatic Cancer AJCC v8
Interventions: PROCEDURE: Computed Tomography|DRUG: Gallium Ga 68 FAPi-46|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Recombinant Human Growth Hormone (rhGH) on Abdominal Fat and Cardiovascular Risk in Obese Girls
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: recombinant human growth hormone (rhGH)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Contribution of F18-FDG PET/CT to the Early Assessment of Pazopanib Therapy Efficacy in Advanced Soft Tissue Sarcoma
Status: UNKNOWN
Conditions: Soft Tissue Sarcoma (STS)
Interventions: OTHER: F18-FGD PET/CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Validation of the European Oncology Quality of Life Toolkit
Status: NOT_YET_RECRUITING
Conditions: Cancer|Survivorship|Palliative Care
Interventions: OTHER: Administration of the EUonQoL-Kit - Active Treatment questionnaire|OTHER: Administration of the EUonQoL-Kit - Survivors questionnaire|OTHER: Administration of the EUonQoL-Kit - Palliative Care questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tiragolumab Plus Atezolizumab Versus Atezolizumab in the Treatment of Stage II Melanoma Patients Who Are ctDNA-positive Following Resection
Status: TERMINATED
Conditions: Stage II Melanoma
Interventions: DRUG: Atezolizumab|DRUG: Tiragolumab|DEVICE: Signatera Assay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PSMA-PET to Guide Prostatectomy
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: PSMA-PET and SOC MRI|DIAGNOSTIC_TEST: SOC MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunotherapy of Neuroblastoma Patients Using a Combination of Anti-GD2 and NK Cells
Status: UNKNOWN
Conditions: Neuroblastoma Recurrent
Interventions: BIOLOGICAL: Anti-GD2 in combination with NK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stellate Ganglion Destruction With Alcohol Versus Thermal Ablation for Chronic Post Mastectomy Pain
Status: RECRUITING
Conditions: Post-mastectomy Pain Syndrome
Interventions: DEVICE: thermal Radiofrequency neurolysis of Stellate ganglion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-30979754 (Decitabine) in Patients With Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: JNJ-30979754 15 mg/m2|DRUG: JNJ-30979754 20 mg/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the Physical Activity Program in Women With Post-menopausal Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal|Physical Activity
Interventions: OTHER: Physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Image Quality: Ultra-Low Dose Scanner Versus Standard Dose Conventional Scanner for Thoraco-abdominopelvic Scans
Status: NOT_YET_RECRUITING
Conditions: Imaging, Diagnostic|Lung Diseases|Abdomen Disease|Pelvis Disease|Bone Diseases
Interventions: RADIATION: Ultra-Low-Dose thoraco-abdominopelvic scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intervention Study to Enhance Patients' Pain Management After Cardiac Surgery
Status: COMPLETED
Conditions: Pain|Pain, Postoperative|Other Functional Disturbances Following Cardiac Surgery
Interventions: BEHAVIORAL: Pain Booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Deep Brain Therapy With Low-intensity Ultrasound for Generalized Chronic Pain
Status: RECRUITING
Conditions: Chronic Pain|Chronic Pain Syndrome|Widespread Chronic Pain
Interventions: DEVICE: Verum stimulation with Diadem prototype|DEVICE: Sham stimulation with Diadem prototype
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT