pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Brief Trainings to Buffer Against Acute Stress Effects
Status: COMPLETED
Conditions: Stress
Interventions: BEHAVIORAL: Loving-Kindness meditation training|BEHAVIORAL: Breath Awareness meditation training|BEHAVIORAL: Gratitude|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: HIV Infection And Evolvement of Atherosclerotic Plaque
Status: UNKNOWN
Conditions: Coronary Artery Disease|Atherosclerosis, Coronary|Hiv|HIV Infections|Stable Chronic Angina
Interventions: RADIATION: Quantitative coronary angiography, intravascular imaging with percutaneous intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot Study of Immunization With HIV-1 Antigen Pulsed Allogenic Dendritic Cells in HIV-Infected Asymptomatic Patients With CD4+ T Cells > 350 Cells/mm3
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: Allogenic Dendritic Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Use of Static Ultrasound Guidance for Internal Jugular Vein Cannulation in Adult Cardiac Surgical Patients
Status: COMPLETED
Conditions: Adult Cardiac Surgical Patients
Interventions: PROCEDURE: landmark technique|DEVICE: Static Ultrasound technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Effect of a Deep Learning-based Bile Duct Scanning System on the Diagnostic Accuracy of Common Bile Duct Stones During Examination by Novice Ultrasound Endoscopists
Status: UNKNOWN
Conditions: Common Bile Duct Stones
Interventions: DEVICE: artificial intelligence assistance system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The LINFU® U.S. Registry in Patients With IPMN (Intraductal Papillary Mucinous Neoplasm of the Pancreas)
Status: NOT_YET_RECRUITING
Conditions: IPMN, Pancreatic|Pancreas Cancer|Pancreatic Cyst
Interventions: DIAGNOSTIC_TEST: LINFU®|DIAGNOSTIC_TEST: Standard imaging tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Intravitreal Ranibizumab Injection With Retinal Vein Occlusion (RVO)
Status: COMPLETED
Conditions: Macular Edema|Retinal Vein Occlusion
Interventions: DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Chidamide Combined With Cladribine in Refractory/Relapsed Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Chidamide|DRUG: Cladribine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Providing Optimal PEEP During Mechanical Ventilation for Obese Patients Using Esophageal Balloon
Status: TERMINATED
Conditions: Obesity, Morbid|Ventilator-Induced Lung Injury|Respiratory Failure
Interventions: DEVICE: Esophageal balloon|PROCEDURE: Intervention Spontaneous Breathing Trial (SBT) and Extubation|PROCEDURE: Control Spontaneous Breathing Trial and Extubation|PROCEDURE: Intervention Weaning after Tracheostomy|PROCEDURE: Control Weaning after Tracheostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Metabolic Effects of LCZ696 and Amlodipine in Obese Hypertensive Subjects
Status: COMPLETED
Conditions: Hypertension|Concurrent Obesity
Interventions: DRUG: LCZ696|DRUG: amlodipine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Early Genetic Identification of Obesity
Status: RECRUITING
Conditions: Obesity, Childhood|Hyperphagia|Retinopathy|Syndactyly|Polydactyly|Cognitive Impairment|Bardet-Biedl Syndrome|POMC Deficiency
Interventions: DIAGNOSTIC_TEST: Genetic testing via blood collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study for the Treatment of Persistent Allergic Rhinitis With Desloratadine (Study P04684)
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: 5-mg Desloratadine|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Remote Ischemic Preconditioning Improve Long-term Prognosis of Acute Myocardial Infarction Patients Without Emergency Reperfusion Therapy
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: OTHER: reported remote ischemic preconditioning (RIPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventive Effects of Ginseng Against Atherosclerosis
Status: COMPLETED
Conditions: Ischemic Stroke|Atherosclerosis
Interventions: DIETARY_SUPPLEMENT: Ginseng|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: POETIC Plerixafor as a Chemosensitizing Agent for Relapsed Acute Leukemia and MDS in Pediatric Patients
Status: COMPLETED
Conditions: Relapsed/Refractory AML|Relapsed/Refractory ALL|Secondary AML/MDS|Acute Leukemia of Ambiguous Lineage|AML|ALL
Interventions: DRUG: Plerixafor Dose Escalation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics in the Reduction of Antibiotic Associated Diarrhea
Status: TERMINATED
Conditions: Clostridium Difficile
Interventions: DIETARY_SUPPLEMENT: Florajen-3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Intramuscular Epinephrine as an Adjunctive Treatment for Severe Pediatric Asthma Exacerbation
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: IM epinephrine 1:1000|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Definition of Links Between Non-invasives Methods and Intracerebral EEG With Simultaneous Recordings.
Status: COMPLETED
Conditions: Epilepsy
Interventions: DEVICE: electroencephalogram|DEVICE: magnetoencephalogram
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cost-effectiveness of Forced Aerobic Exercise for Stroke Rehabilitation
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke|Cerebrovascular Disorders|Brain Diseases|Central Nervous System Diseases|Nervous System Diseases|Vascular Diseases|Cardiovascular Diseases
Interventions: BEHAVIORAL: Aerobic Exercise|BEHAVIORAL: Upper Extremity Repetitive Task Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Dupuytren's Disease With Minimal Invasive Surgery and VIVOSORB® Resorbable Implant Device
Status: ACTIVE_NOT_RECRUITING
Conditions: Dupuytren Contracture|Dupuytren Disease of Palm and Finger
Interventions: DEVICE: Vivosorb
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Local Anesthesia in Patients With Marginal Periodontitis Undergoing Scaling and Root Planning
Status: TERMINATED
Conditions: Pain and Discomfort During Scaling and Root Planning of Patients With|Periodontitis
Interventions: DRUG: Bupivacaine lozenge|DRUG: Lidocaine-adrenalin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Efficacy of an Experimental Occlusion Technology Dentifrice in Dentinal Hypersensitivity
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: OTHER: Stannous fluoride (SnF2)|OTHER: Sodium monofluorophosphate (SMFP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of DHA-NAT on Postprandial Lipidaemia in Healthy Male Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertriglyceridemia
Interventions: OTHER: DHA-NAT|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Local Injection of Steroid VS.Glucose 5% in Carpal Tunnel Syndrome
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: Dexamethasone|DRUG: Glucose Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Learning to PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia
Status: COMPLETED
Conditions: Lewy Body Disease|Parkinson Disease Dementia|Dementia With Lewy Bodies
Interventions: BEHAVIORAL: Peer mentor support and caregiver intervention|OTHER: Focus group to provide feedback on educational materials and mentoring program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Microfracture at Proximal Humerus Lateral to Footprint Could Enhance the Rotator Cuff Healing
Status: RECRUITING
Conditions: Rotator Cuff Tears|Micro Fracture
Interventions: PROCEDURE: Lateralised microfracture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Overall Performance of the Zalviso System™ (Sufentanil Sublingual Tablet System) 15 mcg
Status: COMPLETED
Conditions: Moderate-to-severe Acute Pain
Interventions: DRUG: Zalviso™ 15 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Personalized Dietary Intervention for the Control of Essential Hypertension
Status: UNKNOWN
Conditions: Essential Hypertension
Interventions: OTHER: PCFA interventional dietary counselling|OTHER: conventional DASH diet counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Safety, Tolerance, and Metabolism of Abacavir (1592U89, ABC) With Standard Zidovudine (ZDV) Therapy in Newborn Infants Born to HIV-1 Infected Women
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Abacavir sulfate|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of Multiple Oxygenation Targets With Different Oximeters in Chronic Obstructive Pulmonary Disease (COPD) and Non-COPD Patients- Impact on Oxygen Flows
Status: NOT_YET_RECRUITING
Conditions: COPD Exacerbation|Pneumonia|Hypoxemia|Respiratory Disease
Interventions: DEVICE: Masimo oximeter|DEVICE: Nellcor oximeter|DEVICE: Nonin oximeter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain Control in Septum and Sinus Surgery
Status: COMPLETED
Conditions: Post-operative Pain|Sinus Surgery
Interventions: DRUG: Acetaminophen 325 mg Oral Tablet|DRUG: Acetaminophen 650 mg Oral Tablet|DRUG: OxyCODONE 5 mg Oral Tablet|DRUG: Acetaminophen/Hydrocodone 325 mg/7.5 mg oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor-specific Allogeneic Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia (ALL)
Status: TERMINATED
Conditions: Acute Lymphoid Leukemia
Interventions: PROCEDURE: alloHCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAPSAICIN Trial: Assessing Capsaicin as a Chemopreventive Agent for Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: Capsaicin Supplement (Cayenne by Nature's Way)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Defining The Role Of Dialysate Magnesium In Arrhythmogenicity On Dialysis
Status: COMPLETED
Conditions: Chronic Kidney Disease|Arrhythmia
Interventions: DRUG: Dialysate Magnesium (Concentration)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Interest of Non Invasive Brain Stimulation During Physiotherapy at a Subacute Phase Post Stroke (Anodal Protocol): ReSTIM
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: anodal tDCS (device) Eldith DC-Stimulator|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Cervical Pessary Prevent Spontaneous Preterm Birth in Twin Pregnancies With Short Cervical Length?
Status: UNKNOWN
Conditions: Preterm Birth
Interventions: DEVICE: Cervical pessary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Hoodia on Blood Pressure and Heart Function
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Hoodia Gordonii|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Involvement of Breast Cancer Patients During Oncological Consultations
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: prompt-sheet|BEHAVIORAL: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cancer Loyalty Card Study 2 (CLOCS-2)
Status: RECRUITING
Conditions: Pancreatic Cancer|Colon Cancer|Oesophageal Cancer|Stomach Cancer|Liver Cancer|Bladder Cancer|Uterine Cancer|Vulvar Cancer|Ovarian Cancer|Endometrial Cancer
Interventions: OTHER: Cases & Controls
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Outcomes of Liver Transplantation in Low Weight Children After Reducing the Lateral Segment of a Living Donor, Adapting the Shape and Size of the Graft to the Needs of the Recipient
Status: COMPLETED
Conditions: Liver Transplantation|Low-weight Children|Hyper-reduced Liver Grafts
Interventions: PROCEDURE: Liver transplantation with hyper-reduced grafts
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HMPL-004 Maintenance Treatment in Subjects With Mild to Moderate Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: HMPL-004|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Community Health Azithromycin Trial in Burkina Faso
Status: COMPLETED
Conditions: Childhood Mortality
Interventions: DRUG: Azithromycin|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Location of Injection of Local Anesthetics in the Adductor Canal Block
Status: COMPLETED
Conditions: Anesthesia|Adductor Canal Block
Interventions: DRUG: lidocaine|DRUG: ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Middle Age muScle Krill Study
Status: RECRUITING
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Krill oil|DIETARY_SUPPLEMENT: Vegetable oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Underwater Versus Conventional Endoscopic Mucosal Resection in the Treatment of Non-pedunculated Colorectal Polyps
Status: RECRUITING
Conditions: Colorectal Polyp|Colorectal Neoplasms
Interventions: PROCEDURE: Endoscopic resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to See How Low Level Laser Light Affects Subcutaneous Fat Around the Hips and Waist
Status: WITHDRAWN
Conditions: Weight Loss
Interventions: DEVICE: Erchonia MLS|DEVICE: Placebo Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Sudy: Resectable Esophageal Adenocarcinoma and the Relevance of CTC
Status: COMPLETED
Conditions: Esophageal Adenocarcinoma
Interventions: PROCEDURE: Blood Test for CTC evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Ondansetron for Withdrawal Symptoms
Status: COMPLETED
Conditions: Substance Withdrawal Syndrome
Interventions: DRUG: Ondansetron and Placebo crossover
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ketamine, Amitriptyline and Their Combination on Histaminergic and Non-histaminergic Itch
Status: NOT_YET_RECRUITING
Conditions: Itch
Interventions: DRUG: Ketamine 0.5%|DRUG: Amitriptyline|DRUG: ketamine + amitriptyline|OTHER: Vehicle|OTHER: Histamine|OTHER: Cowhage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Determine Acute (After First Dose) and Chronic (After 28 Days) Effects of Empagliflozin (BI 10773) on Pre and Postprandial Glucose Homeostasis in Patients With Impaired Glucose Tolerance and Type 2 Diabetes Mellitus and Healthy Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: BI 10773
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Amount of EI-1071 in Blood in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: EI-1071|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Re-Purposing the Ordering of 'Routine' Laboratory Tests in Hospitalized Medical Patients (RePORT Study)
Status: RECRUITING
Conditions: Utilization, Health Care
Interventions: OTHER: Multimodal Intervention: Education|OTHER: Multimodal Intervention: Audit and Feedback|OTHER: Multimodal Intervention: Patient Engagement|OTHER: Multimodal Intervention: System Changes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Immunogenicity and Thrombotic Potential of Circulating Protamine-heparin Complexes in Cardiac Surgery Patients
Status: COMPLETED
Conditions: Thrombocytopenia|Antibodies Drug Specific
Interventions: DIAGNOSTIC_TEST: "ZYMUTEST™ HIA" immunoglobulin g ELISA (enzyme-linked immunosorbent assay )
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Challenge of Obtaining Qualitative Bacterial Cultures in Non-expectorating Cystic Fibrosis Patients
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: PROCEDURE: Nasal swab|PROCEDURE: Cough swab|PROCEDURE: Spontaneous expectorated sputum|PROCEDURE: Induced sputum|PROCEDURE: Bronchoalveolar lavage|OTHER: Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Iraq- Afghanistan War Lung Injury Using 19F MRI (DIAL1001006)
Status: COMPLETED
Conditions: Constrictive Bronchiolitis|Iraq-Afganistan War Lung Injury Syndrome
Interventions: DIAGNOSTIC_TEST: Perfluorinated Gas/Oxygen Mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: RAD001 Therapy of Angiomyolipomata in Patients With TS Complex and Sporadic LAM
Status: COMPLETED
Conditions: Tuberous Sclerosis|Lymphangioleiomyomatosis
Interventions: DRUG: RAD001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Aromatherapy on the Headache and Service Quality Among Nurses Working in Critical Care Nurses Units.
Status: UNKNOWN
Conditions: Headache, Migraine|Quality of Life
Interventions: DEVICE: Necklace with essential oil for the first 4 weeks|DEVICE: Necklace without essential oil for the first 4 weeks|OTHER: Washout|DEVICE: Necklace with essential oil for last 4 weeks|DEVICE: Necklace without essential oil for last 4 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Accuracy of Continuous Glucose Monitoring (CGM) in Patients With End Stage Renal Disease (ESRD) on Intermittent Hemodialysis (iHD).
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DEVICE: Continuous Glucose Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: eOSS-ATTR Study (eHealth Based Operative Support System in ATTR-CM)
Status: NOT_YET_RECRUITING
Conditions: Heart Failure|Amyloid Cardiomyopathy|ATTR Amyloidosis Wild Type|ATTR Gene Mutation
Interventions: PROCEDURE: mHealth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study for Naltrexone on the Abuse Potential of Methylphenidate
Status: COMPLETED
Conditions: Naltrexone|Methylphenidate Abuse
Interventions: DRUG: Placebo|DRUG: Methylphenidate 60 mg|DRUG: Treatment Phase Sequence 4213|DRUG: Treatment Phase Sequence 2134|DRUG: Treatment Phase Sequence 1342|DRUG: Treatment Phase Sequence 3421
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Preference Between a Prefilled Syringe or a Prefilled Pen Device for Administration of Pegfilgrastim
Status: ACTIVE_NOT_RECRUITING
Conditions: Patient Preference|Febrile Neutropenia, Drug-Induced|Patient Satisfaction
Interventions: DEVICE: PELGRAZ prefilled syringe or PELGRAZ prefilled pen
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Music on Satisfaction, Anxiety, and Hemodynamics During Spinal Anesthesia for Cesarean Delivery
Status: COMPLETED
Conditions: Anxiety|Hypotension
Interventions: OTHER: Pandora Music|OTHER: Mozart Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tourniquet Abstention on Pain Reduction in Venous Sampling in the Elderly People
Status: RECRUITING
Conditions: Venous Puncture
Interventions: PROCEDURE: Rubber tourniquet|PROCEDURE: Fabric tourniquet|PROCEDURE: Without tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigation of Brain Plasticity in Autism Spectrum Disorders
Status: UNKNOWN
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Neuropsychological Testing|GENETIC: (Optional) Saliva Collection|DEVICE: Sensory Testing|DEVICE: Electroencephalogram (EEG)|DEVICE: Transcranial Magnetic Stimulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Investigate the Safety and Effectiveness of Different Doses of Sprifermin in Participants With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Sprifermin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dynamic Respiratory Muscle Function in Late-Onset Pompe Disease
Status: COMPLETED
Conditions: Pompe Disease
Interventions: OTHER: Thoracic MRI|OTHER: Spirometry|OTHER: Inspiratory Load Compensation|OTHER: Maximal Inspiratory Pressure|OTHER: Resting Breathing Pattern|OTHER: Respiratory Muscle Endurance Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Genomic Effects of Glucocorticoids in Patients With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematous (SLE)
Interventions: DRUG: Solu-Medrol 1mg/kg|DRUG: Solu-Medrol 250 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Toxoplasmic Encephalitis in Patients With AIDS. Treatment and Prevention of Relapse
Status: COMPLETED
Conditions: Toxoplasmosis, Cerebral|HIV Infections
Interventions: DRUG: Pyrimethamine|DRUG: Clindamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Creatine Supplementation and Exercise on Bone Health
Status: COMPLETED
Conditions: Osteoporosis|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Creatine monohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oral SM-88 in Patients With Metastatic HR+/HER2- Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Metastatic Breast Cancer|Hormone Receptor Positive Breast Carcinoma
Interventions: DRUG: SM-88
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbrella Trial Testing Integrative Subtype Targeted Therapeutics in Estrogen Receptor Positive, HER2-Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|HER2-negative Breast Cancer|ER Positive Breast Cancer
Interventions: DRUG: Alpelisib|DRUG: Tamoxifen|DRUG: Zotatifin|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab, Gemcitabine, and Oxaliplatin Followed By Surgery or External-Beam Radiation Therapy and Capecitabine in Treating Patients With Locally Advanced, Nonmetastatic Pancreatic Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: capecitabine|DRUG: oxaliplatin|PROCEDURE: conventional surgery|RADIATION: radiation therapy|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefit of GnRH Agonist Before Frozen Embryo Transfer in Patients With Endometriosis and/or Adenomyosis
Status: RECRUITING
Conditions: Endometriosis|Adenomyosis|Infertility, Female
Interventions: DRUG: GnRH agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Hydrocortisone Administered for the Prevention of Pulmonary Bronchodysplasia (PREMILOC Trial) on the Determinants of Systemic Blood Pressure in Children (PREMILOCAP)
Status: RECRUITING
Conditions: Infant, Premature, Diseases
Interventions: DIAGNOSTIC_TEST: blood pressure measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A 12-Week Placebo-Controlled Study to Investigate the Efficacy, Safety, and Tolerability of RO7017773 in Participants Aged 15-45 Years With Autism Spectrum Disorder (ASD)
Status: COMPLETED
Conditions: Autism Spectrum Disorder (ASD)
Interventions: DRUG: Placebo|DRUG: RO7017773
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of tDAS Combined With Stabilization Exercises in Individuals With Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Transcranial Direct Current Stimulation|OTHER: Cervical Stabilization Exercises|OTHER: Sham-Transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assisted Promontofixation Using Glue Versus Promontofixation Using Threads (PROCOL)
Status: COMPLETED
Conditions: Prolapse
Interventions: PROCEDURE: Laparostopic promontofixation using surgical glue|PROCEDURE: Laparostopic promontofixation using threads
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Glossopharyngeal Nerve Block for Awake Intubation
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: DRUG: 2% Lidocaine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effectiveness of Chlorhexidine Bathing in the Neonatal Intensive Care Unit
Status: TERMINATED
Conditions: Infectious Disease Transmission
Interventions: OTHER: washcloths impregnated with 2% chlorhexidine gluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Non Invasive Electrical Stimulation Therapy on Gastroesophageal Reflux Disease (GERD) Symptoms - Proof of Concept Study
Status: UNKNOWN
Conditions: Gastroesophageal Reflux Disease
Interventions: DEVICE: TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stenting Versus Neurosurgical Treatment of Idiopathic Intracranial Hypertension.
Status: RECRUITING
Conditions: Pseudotumor Cerebri|Cerebrospinal Fluid|Transverse Sinuses
Interventions: PROCEDURE: venous sinus stenting|PROCEDURE: Neurosurgical internal ventricular shunt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of Imetelstat in Combination With Ruxolitinib in Participants With Myelofibrosis
Status: RECRUITING
Conditions: Myelofibrosis
Interventions: DRUG: Imetelstat|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of Vitamin D Supplementation on Salivary Biomarkers and Cariogenic Oral Microbiome
Status: RECRUITING
Conditions: Dental Caries|White Spot Lesion|Initial Caries|Incipient Enamel Caries
Interventions: DIETARY_SUPPLEMENT: Vitamin D supplements along with behavioral modification|COMBINATION_PRODUCT: Topical fluoride application and Vitamin D supplements along with behavioral modification|PROCEDURE: Topical fluoride application along with behavioral modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of High Dose PROton Therapy On Unresectable Primary Carcinoma Of Liver: Prospective Phase II Trial
Status: UNKNOWN
Conditions: Liver Neoplasm|Proton Therapy
Interventions: RADIATION: Proton arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dental Hygiene and Peri-Implant Tissues Homeostasis Ancillary Study
Status: COMPLETED
Conditions: Peri-Implantitis
Interventions: PROCEDURE: Peri-implantitis debridement|OTHER: Dental hygiene procedures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Wireless, Implantable Tibial Nerve Stimulator System for the Treatment of Refractory Lower Urinary Tract Symptoms in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DEVICE: StimRouter®, Self-activated and self-controlled neuromodulation device (Bioness Inc, CE0086).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Dose Clinical Trial to Study the Safety of ART-I02 in Patients With Arthritis
Status: UNKNOWN
Conditions: Arthritis, Rheumatoid|Osteo Arthritis
Interventions: GENETIC: ART-I02
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy
Status: RECRUITING
Conditions: Locally Advanced Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: volrustomig
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Attentional Bias Modification
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: Attention Bias Modification (ABM) for depression|BEHAVIORAL: Sham Attention Bias Modification (ABM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Anamorelin HCl for the Treatment of Malignancy Associated Weight Loss and Anorexia in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Cachexia; Cancer|Non Small Cell Lung Cancer
Interventions: DRUG: anamorelin HCl|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Observational Prospective Study.at the End of the Study the Patients Will be Classified According to PH,Serum Bicarbonate and Serum Sodium Into 6 Groups and Statistical Analysis Will be Performed Using Spss
Status: COMPLETED
Conditions: Liver Cirrhosis
Interventions: DIAGNOSTIC_TEST: arterial blood gases and serum electrolytes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Dupilumab in Patients With Atopic Keratoconjunctivitis (AKC)
Status: RECRUITING
Conditions: Atopic Keratoconjunctivitis
Interventions: DRUG: Dupilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Ventilation in ALS Patients With Mild Respiratory Involvement
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DEVICE: noninvasive positive pressure ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination of Brivanib With 5-Fluorouracil/Leucovorin (5FU/LV) and 5-Fluorouracil/Leucovorin/Irinotecan (FOLFIRI)
Status: COMPLETED
Conditions: Gastro-Intestinal Cancer
Interventions: DRUG: 5-FU|DRUG: Leucovorin|DRUG: 5-FU|DRUG: Irinotecan|DRUG: Brivanib|DRUG: Brivanib|DRUG: Brivanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of Empagliflozin in the US
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Empagliflozin|DRUG: DPP-4 inhibitor|DRUG: GLP-1 receptor agonist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Robot-Assisted Laparoscopic High-Intensity Focused Ultrasound and Radical Cystectomy for Thermal Ablation of Muscle Invasive Cells in Patients With Bladder Tumors
Status: WITHDRAWN
Conditions: Infiltrating Bladder Urothelial Carcinoma|Stage II Bladder Urothelial Carcinoma|Transitional Cell Carcinoma
Interventions: PROCEDURE: Biopsy|DEVICE: High-Intensity Focused Ultrasound Ablation|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Radical Cystectomy|DEVICE: Ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accuracy and Safety of Endobronchial Ultrasound (EBUS) in Suspected Non-malignant Mediastinal Lymphadenopathy
Status: UNKNOWN
Conditions: Mediastinal Lymphadenopathy
Interventions: PROCEDURE: EBUS with TBNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ST Elevation Myocardial Infarction Hemodynamic OutComes: Role of Non-Invasive Cardiac System (SHOCk-NICaS) Study
Status: RECRUITING
Conditions: ST Elevation Myocardial Infarction (STEMI) Patients
Interventions: DEVICE: Non-Invasive Cardiac System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Dose-finding Trial of OPC-34712 in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: OPC-34712|DRUG: OPC-34712|DRUG: OPC-34712|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for Treatment of Paroxysmal Atrial Fibrillation (PAF) by Pulsed Field Ablation (PFA) System With Irreversible Electroporation (IRE)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Pulsed Field Ablation (PFA) Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flotetuzumab for Relapsed Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Following Allogeneic Hematopoietic Cell Transplantation (Allo-HCT)
Status: TERMINATED
Conditions: Relapsed Acute Myeloid Leukemia
Interventions: DRUG: Flotetuzumab|PROCEDURE: Donor lymphocyte infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Nerve Denervation in Patients With Hypertension and Paroxysmal and Persistent Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Hypertension
Interventions: DEVICE: Symplicity Spyral™ Multi-Electrode Renal Denervation Catheter|DEVICE: Arctic Front Advance™ Cardiac Cryoablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3)
Status: RECRUITING
Conditions: Vulvar Diseases|HPV Infection|Vulvar HSIL|Pre-Cancerous Dysplasia|HPV Disease|VIN, Usual Type|VIN 2 of Usual Type|VIN 3 of Usual Type|Vin II|Vin III|VIN Grade 2|VIN Grade 3|High Grade Intraepithelial Neoplasia
Interventions: DRUG: Artesunate ointment|DRUG: Placebo ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Suturing Technique on Height of Interdental Papilla and Periodontal Healing
Status: UNKNOWN
Conditions: Gingival Papillary Blunting
Interventions: PROCEDURE: CISS|PROCEDURE: VIMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of YuWell YE660D Blood Pressure Monitor in General Population According to the ISO 81060-2:2018
Status: COMPLETED
Conditions: Blood Pressure
Interventions: DIAGNOSTIC_TEST: YuWell YE660D Electronic Sphygmomanometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intraoperative Nasal Insulin Effect on Plasma and CSF Insulin Concentration and Blood Glucose
Status: UNKNOWN
Conditions: Ischemic Heart Disease|Aortic Aneurysm
Interventions: DRUG: Humulin R|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Comparing Oral Calcitonin to Nasal Spray Calcitonin in Postmenopausal Osteoporotic Women
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: Oral Calcitonin Tablets|DRUG: Intranasal Calcitonin|DRUG: Placebo tablets and placebo intranasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Combined With Erlotinib, Tipifarnib, or Temsirolimus in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma
Status: COMPLETED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Tumor
Interventions: DRUG: sorafenib tosylate|DRUG: erlotinib hydrochloride|DRUG: tipifarnib|DRUG: temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Ranibizumab in Proliferative Diabetic Retinopathy (PDR) Requiring Vitrectomy
Status: UNKNOWN
Conditions: Proliferative Diabetic Retinopathy
Interventions: DRUG: Lucentis (ranibizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Precision Medical Research of Non-immune Fetal Hydrops (NIFH)-From Prenatal Diagnosis to Intrauterine Treatment
Status: UNKNOWN
Conditions: Fetal Hydrops
Interventions: PROCEDURE: intrauterine intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predicting Ventilator-associated Lower Respiratory Tract Infection Outcomes Using Sequenced-based Early Microbiological Response: A Multi-center Prospective Study
Status: RECRUITING
Conditions: Pneumonia, Ventilator-Associated|Respiratory Tract Infections|Prognosis
Interventions: PROCEDURE: bronchoscope
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PSMA-based 18F-DCFPyL PET/CT and PET/MRI Pilot Studies in Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Prostate Neoplasm
Interventions: DRUG: 18F-DCFPyL PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multiple Ascending Dose (MDX1105-01)
Status: COMPLETED
Conditions: Cancer, Multiple Indications
Interventions: BIOLOGICAL: Anti-PDL-1 antibody|BIOLOGICAL: Anti-PDL-1 antibody|BIOLOGICAL: Anti-PDL-1 antibody|BIOLOGICAL: Anti-PDL-1 antibody|BIOLOGICAL: Anti-PDL-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enabling Remote Access to Breathe Easier: A Novel Approach to Improve Symptom Management
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer, Nonsmall Cell|Lung Cancer Stage I|Lung Cancer Stage II|Lung Cancer Stage III
Interventions: OTHER: Breathe Easier Progressive Web Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness and Safety of Outpatient Treatment of Uncomplicated Acute Diverticulitis Without Antibiotics
Status: NOT_YET_RECRUITING
Conditions: Diverticulitis, Colonic
Interventions: DRUG: Antibiotic|OTHER: Non antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of BI 201335 (Faldaprevir) in Combination With Pegylated Interferon-alpha and Ribavirin in Treatment-Experienced Genotype 1 Hepatitis C Infected Patients (STARTverso 3)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: BI 201335|DRUG: Pegylated Interferon-alpha (IFN)|DRUG: Ribavirin (RBV)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Observational Study to Evaluate the Current Neuromuscular Monitoring Practice Used After Different Types of Surgery, for Which Neuromuscular Blocking Agents Were Used, With or Without Blocking Reversal (P06556)
Status: COMPLETED
Conditions: Neuromuscular Monitoring After Administration of Neuromuscular Blocking Agents in Different Types of Surgery
Interventions: OTHER: No neuromuscular blockade (NMB)-reversal agent used|DRUG: Sugammadex|DRUG: Other NMB-Reversal Agents Used in Routine Anesthesiology Practice
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p