pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: NeoVas Bioresorbable Coronary Scaffold Randomized Controlled Trial
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: NeoVas BCS|DEVICE: XIENCE PRIME EECSS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination Neoadjuvant Chemotherapy With or Without Apatinib for HER2 Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Apatinib|DRUG: Paclitaxel|DRUG: Cisplatin|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Existential Group Treatment for Older Adults (75+) With Psychological Distress in Primary Care
Status: RECRUITING
Conditions: Psychological Distress
Interventions: BEHAVIORAL: Existential group treatment|BEHAVIORAL: Supportive telephone calls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Gamma Tocopherol Supplementation on Neutrophil Response to 20,000 EU of Clinical Center Reference Endotoxin in Normal Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: gamma tocopherol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of UCB0022 in Study Participants With Advanced Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: OTHER: Placebo|DRUG: UCB0022
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: XENITH: Rivaroxaban for Pulmonary Embolism Managed With Catheter Directed Thrombolysis
Status: TERMINATED
Conditions: Pulmonary Embolism|Venous Thrombosis
Interventions: DRUG: rivaroxaban|DRUG: warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating DVS-233 SR to Treat Vasomotor Systems Associated With Menopause
Status: COMPLETED
Conditions: Menopause|Hot Flashes|Sleep Disorders
Interventions: DRUG: DVS-233 SR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Recombinant Omicron-Delta COVID-19 Vaccine (CHO Cell)
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Recombinant Omicron-Delta COVID-19 Vaccine (CHO Cell)|BIOLOGICAL: Inactivated COVID-19 vaccine (Vero Cell)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy Parecoxib and Ketorolac as Preemptive Analgesia in Spine Fusion
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Parecoxib|DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Learn About How Safe BAY3018250 is and What Happens to it in Healthy Japanese Men and Adult Participants Aged 18 to 55 Years
Status: NOT_YET_RECRUITING
Conditions: Acute Venous and Arterial Thrombotic and Thromboembolic Events|Healthy Volunteers
Interventions: DRUG: BAY3018250 Dose 1|DRUG: Placebo|DRUG: Placebo|DRUG: BAY3018250 Dose 2 infusion|DRUG: BAY3018250 Dose 2 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: AZD8186 First Time In Patient Ascending Dose Study
Status: COMPLETED
Conditions: Advanced Castrate-resistant Prostate Cancer CRPC|Squamous Non-Small Cell Lung Cancer sqNSCLC|Triple Negative Breast Cancer TNBC
Interventions: DRUG: Part A: AZD8186 monotherapy|DRUG: Part B: AZD8186 monotherapy|DRUG: Part C1: Abiraterone acetate combination with AZD8186|DRUG: Part D1: AZD2014 combination with AZD8186|DRUG: Part D2 AZD2014 combination with AZD8186|DRUG: Part C2: Abiraterone acetate combination with AZD8186
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Versus Secondary Metal Stent Implantation in PTBD
Status: COMPLETED
Conditions: Bile Duct Obstruction|Extrahepatic Cholestasis
Interventions: DEVICE: Percutaneous transhepatic implantation of self-expandable metal stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT Mesenchymal Stem Cells Versus Hyaluronic Acid in OA Knee):
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: Autologous Mesenchymal Stem Cells Treatment (MSCs)|DRUG: Hyaluronic acid (HA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Insulin Intensification of Biphasic Insulin Aspart 30 and Insulin Analogues (Insulin Glargine and Insulin Aspart) in Insulin naïve Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 30|DRUG: insulin glargine|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Electrotherapy Techniques to Treat Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DEVICE: Sham Transcutaneous nerve stimulation|DEVICE: Transcutaneous nerve stimulation|DEVICE: Interferential currents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Trial: Multi-dosing the BCG Vaccine for Fibromyalgia
Status: WITHDRAWN
Conditions: Fibromyalgia
Interventions: BIOLOGICAL: Bacillus Calmette Guerin Vaccine|BIOLOGICAL: Saline Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesia in Knee Arthroscopic Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Dexamethasone|DRUG: Dexmedetomidine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 3D Printed Titanium Mesh vs Guided Autogenous Graft
Status: UNKNOWN
Conditions: Orbital Floor (Blow-Out) Open Fracture|Enophthalmos Traumatic
Interventions: DEVICE: orbital floor recontriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Non-invasive Assessment of Blood Pressure in Bariatric Surgery
Status: COMPLETED
Conditions: Bariatric Surgery|Arterial Blood Pressure
Interventions: PROCEDURE: baseline alert 1|PROCEDURE: Anti-Trendelenburg-position (ATB)|PROCEDURE: ATB in narcosis|PROCEDURE: baseline in narcosis 1|PROCEDURE: passive leg raising|PROCEDURE: volume bolus substitution|PROCEDURE: baseline in narcosis 2|PROCEDURE: start capnoperitoneum|PROCEDURE: ATB plus capnoperitoneum|PROCEDURE: ATB plus capnoperitoneum plus volume bolus substitution|PROCEDURE: ATB loss of capnoperitoneum|PROCEDURE: baseline|PROCEDURE: baseline alert 2|PROCEDURE: torso position rising 30° at the beginning|PROCEDURE: torso position rising 30° at the end
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Neuro-linguistic Programming on Schoolchildren's Performance
Status: COMPLETED
Conditions: Academic Skill Disorder|Child Behavior
Interventions: BEHAVIORAL: Neuro-linguistic program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Hemodiafiltration Plus MCOs on Uremic Toxins Removal
Status: UNKNOWN
Conditions: Hemodiafiltration|Chronic Kidney Disease Requiring Chronic Dialysis
Interventions: OTHER: Theranova 400 membrane|OTHER: FxCordiax 120 membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Pomalidomide in Myelofibrosis With Myeloid Metaplasia
Status: COMPLETED
Conditions: Myelofibrosis With Myeloid Metaplasia|Myeloid Metaplasia|Myelofibrosis
Interventions: DRUG: Pomalidomide|DRUG: Prednisone|DRUG: Placebo to pomalidomide|DRUG: Placebo to prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Tolerability of ALN-APP in Patients With EOAD
Status: RECRUITING
Conditions: Early-Onset Alzheimer Disease
Interventions: DRUG: ALN-APP|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Of Intensive Cervical Traction On Depression, Insomnia, Quality of Life In Patients With Cervical Radiculopathy
Status: COMPLETED
Conditions: Cervical Radiculopathy
Interventions: DEVICE: intensive Cervical Traction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ecological Momentary Intervention of Implementation Intentions Delivered by Text Message to Reduce Cigarette Smoking
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: BEHAVIORAL: Ecological Momentary Implementation Intentions Intervention (EMI-II)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Outcome of Delayed or Standard Prograf Together With Induction Therapy Followed by Conversion to Advagraf in Donation After Cardiac (or Circulatory) Death (DCD) Kidney Transplant Recipients
Status: COMPLETED
Conditions: Kidney Transplant
Interventions: DRUG: Tacrolimus immediate-release formulation|DRUG: Tacrolimus prolonged-release formulation|DRUG: Induction therapy|DRUG: Mycophenolic acid drugs|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Assessment of the Use of Anti-Adhesion Agents to Prevent Pelvic Postoperative Adhesions
Status: COMPLETED
Conditions: Tissue Adhesion|Gynecologic Surgery
Interventions: DEVICE: PROTAHERE Absorbable Adhesion Barrier|DEVICE: Hyalobarrier Gel|OTHER: No treatment|DEVICE: Seprafilm Adhesion Barrier|DEVICE: Gynecare Interceed (TC7) Absorbable Adhesion Barrier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pyrotinib in Combination With Neoadjuvant Chemotherapy in HR+/HER2-, HER4 High Expression Breast Cancer Patients: A Phase II Trial
Status: RECRUITING
Conditions: Breast Cancer|Hormone-receptor Positive Breast Cancer
Interventions: DRUG: Pyrotinib|DRUG: Epirubicin|DRUG: Doxorubicin Hydrochloride Liposome Injection|DRUG: Cyclophosphamide|DRUG: Docetaxel|DRUG: Nab paclitaxel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Large Retained Products of Conception (> 4 cm): Need for an Standardized Procedure.
Status: COMPLETED
Conditions: Placenta, Retained|Placenta; Retention, Fragments, Complicating Puerperium, Without Hemorrhage|Placenta; Retention, Fragments, Complicating Puerperium (Delayed Hemorrhage)|Pregnancy Related|Hysteroscopy / Methods|Retrospective Studies|Vacuum Curettage
Interventions: PROCEDURE: kind of surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 18 to 75 Years of Age Treated With Subcutaneous (SC) Injections of ABBV-154 for Moderately to Severely Active Rheumatoid Arthritis (RA)
Status: TERMINATED
Conditions: Rheumatoid Arthritis (RA)
Interventions: DRUG: ABBV-154|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regular vs. Clear Liquid Diet for Mild to Moderate Acute Pancreatitis
Status: RECRUITING
Conditions: Pancreatitis|Diet, Food, and Nutrition|Diet|Pancreatic Disease|Enteral Nutrition
Interventions: OTHER: Regular diet|OTHER: Clear Liquid Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of St. John's Wort on the Oral Contraceptive Hormone Levonorgestrel
Status: COMPLETED
Conditions: Contraception
Interventions: DIETARY_SUPPLEMENT: Placebo Control (Placebo Herb)|DIETARY_SUPPLEMENT: St. John's Wort|DRUG: Levonorgestrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Viscous Fiber on Postprandial Kalemic Response in Hemodialysis Patients
Status: UNKNOWN
Conditions: Hyperkalemia|Chronic Kidney Disease Requiring Chronic Dialysis
Interventions: DIAGNOSTIC_TEST: Kalemic Response to Orange Juice|DIETARY_SUPPLEMENT: Kalemic Response to Orange Juice with Fiber
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prehab Intervention in Patients Awaiting Total Knee Arthroplasty (TKA)
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Prehab intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oral Niacinamide on Plasma Phosphorus Levels in Peritoneal Dialysis Patients
Status: COMPLETED
Conditions: Hyperphosphatemia
Interventions: DRUG: Niacinamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Nutrilite Memory Builder on the Improvement of Cognitive Function
Status: RECRUITING
Conditions: Cognitive Function
Interventions: DIETARY_SUPPLEMENT: Study product group (Nutrilite Memory Builder)|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Compare the Effects of Lercanidipine Hydrochloride Tablet (Zanidip®) and Felodipine Sustained-Release Tablet for Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Zanidip|DRUG: Felodipine sustained-release tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Effects of the Medial Longitudinal Arch Slope of a Plantar Orthosis
Status: NOT_YET_RECRUITING
Conditions: Pronated Left Foot|Pronated Right Foot
Interventions: DEVICE: Plantar orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: VEGF Trap in Treating Patients With Recurrent, Locally Advanced, or Metastatic Cancer of the Urothelium
Status: COMPLETED
Conditions: Adenocarcinoma of the Bladder|Distal Urethral Cancer|Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter|Proximal Urethral Cancer|Recurrent Bladder Cancer|Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter|Recurrent Urethral Cancer|Squamous Cell Carcinoma of the Bladder|Stage III Bladder Cancer|Stage III Urethral Cancer|Stage IV Bladder Cancer|Transitional Cell Carcinoma of the Bladder|Urethral Cancer Associated With Invasive Bladder Cancer
Interventions: BIOLOGICAL: ziv-aflibercept|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Study in Diabetic Foot Ulcers (DFU), to Evaluate Safety of 0.03% DSC127 Topical Gel in Chronic Use
Status: TERMINATED
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: 0.03% DSC127 topical gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Isoflavone Supplementation Associated With Physical Exercise in the Health Parameters of Postmenopausal Women
Status: COMPLETED
Conditions: Bloodpressure
Interventions: OTHER: exercise|OTHER: isoflavone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Minimally Invasive Surgery Versus Abdominal Surgery in Patients With Early Stage Cervical Cancer
Status: UNKNOWN
Conditions: Uterine Cervical Neoplasm
Interventions: PROCEDURE: minimally invasive surgery|PROCEDURE: open abdominal surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of CAZ-AVI in the Treatment of Infections Due to Carbapenem-resistant G- Pathogens in Chinese Adults
Status: COMPLETED
Conditions: Urinary Tract Infection|Acute Pyelonephritis|Hospital Acquired Pneumonia|Ventilator-associated Pneumonia|Bacteremia|Intra-abdominal Infection
Interventions: DRUG: Zavicefta, Ceftazidime-Avibactam|DRUG: Best Available Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of VPM1002 in Comparison to BCG in Prevention of Tb Infection in Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Mycobacterium Tuberculosis Infection
Interventions: BIOLOGICAL: VPM1002|BIOLOGICAL: BCG SII
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Canagliflozin in Advanced CKD
Status: RECRUITING
Conditions: ESRD|CKD Stage 4|CKD Stage 5
Interventions: DRUG: Invokana 300 mg and 100 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Doses of BIIB063 in Healthy Volunteers
Status: TERMINATED
Conditions: Healthy
Interventions: BIOLOGICAL: BIIB063|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SORD-BILL Vs Conventional Options During Sacral Colpopexy for POP
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: PKS BILL-PKS PlasmaSORD Versus Conventional surgical techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Techniques of Subcutaneous Administration of Fluids Enabled by Human Recombinant Hyaluronidase
Status: COMPLETED
Conditions: Dehydration
Interventions: DRUG: hylenex-facilitated subcutaneous Lactated Ringer's infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Trial of Pivanex and Docetaxel Vs Docetaxel Monotherapy in Patients With Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Pivanex|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Antibody Response of Influenza Vaccination Following Concomitant Exposure to Bimekizumab in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Bimekizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of the Mentor Becker Expander/Breast Implant in Subjects Who Are Undergoing Primary Breast Reconstruction
Status: TERMINATED
Conditions: Breast Reconstruction
Interventions: DEVICE: Mentor Smooth Becker 50 Expander/Breast Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical Site Infiltration of Exparel vs TAP Block With Exparel in Patients Undergoing Laparotomy Via Midline Incision
Status: UNKNOWN
Conditions: Postoperative Pain|Postoperative Nausea and Vomiting|Opioid Use
Interventions: PROCEDURE: TAP Block|PROCEDURE: Surgical Site Infiltration|DRUG: Exparel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of RO5190591 (Danoprevir) in Combination With Pegasys and Copegus in Treatment-Naive Patients With Chronic Hepatitis C Genotype 1 Virus Infection
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Copegus|DRUG: Pegasys|DRUG: Placebo|DRUG: Placebo|DRUG: RO5190591 (Danoprevir)|DRUG: RO5190591 (Danoprevir)|DRUG: RO5190591 (Danoprevir)|DRUG: RO5190591 (Danoprevir)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Body Mass Index and Smartphone Overuse on Cervical Myofascial Pain: A Cross-sectional Study
Status: COMPLETED
Conditions: Cervical Myofascial Pain Syndrome|Smartphone Addiction|Body Weight|Obesity
Interventions: DIAGNOSTIC_TEST: Pain Pressure Threshold (PPT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study to Evaluate the Efficacy and Satisfaction of the Skinceuticals Skin Care Product (CE FERULIC) for Skin Repair Post Fraxel Laser Treatment
Status: NOT_YET_RECRUITING
Conditions: Photo-damaging
Interventions: OTHER: Skinceuticals skin care product(CE)|OTHER: fraxel laser therapy|OTHER: 0.9% normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Change of Gut Microbiome and Symptom After H.Pylori Eradication Therapy in Patients With Functional Dyspepsia
Status: UNKNOWN
Conditions: Dyspepsia
Interventions: DRUG: Tegoprazan 50mg bid + amoxicillin 1000mg bid + clarithromycin 500mg bid for 10 days
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Expectation, Medication and Placebo on Objective and Self-rated Performance During the QbTest
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Paclitaxel (Albumin Bound),Bleomycin And Cisplatin Or Carboplatin for Recurrent Or Metastatic Squamous Cell Carcinoma Of The Head And Neck
Status: RECRUITING
Conditions: Squamous Cell Carcinoma Of The Head And Neck
Interventions: DRUG: PaclitaxelPaclitaxel (Albumin Bound),Bleomycin combined with Cisplatin or Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QUILT-3.067: NANT Triple Negative Breast Cancer (TNBC) Vaccine: Molecularly Informed Integrated Immunotherapy in Subjects With TNBC Who Have Progressed on or After Standard-of-care Therapy.
Status: TERMINATED
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Aldoxorubicin HCl|BIOLOGICAL: N-803|BIOLOGICAL: ETBX-011|BIOLOGICAL: ETBX-051|BIOLOGICAL: ETBX-061|BIOLOGICAL: GI-4000|BIOLOGICAL: GI-6207|BIOLOGICAL: GI-6301|BIOLOGICAL: haNK for Infusion|BIOLOGICAL: avelumab|BIOLOGICAL: bevacizumab|DRUG: Capecitabine|DRUG: Cisplatin|DRUG: Cyclophosphamide|DRUG: 5-Fluorouracil|DRUG: Leucovorin|DRUG: nab-Paclitaxel|PROCEDURE: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Valproate for Mood Swings and Alcohol Use Following Head Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury (TBI)|Alcoholism
Interventions: DRUG: divalproex sodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reverse Innovation in Western Health Care: the ReMotion Prosthetic Knee.
Status: COMPLETED
Conditions: Lower Limb Amputation Above Knee (Injury)|Lower Limb Amputation Knee
Interventions: DEVICE: ReMotion Knee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Evaluating Safety and Efficacy of C-CAR039 Treatment in NHL Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Hodgkin's B-cell Lymphoma
Interventions: BIOLOGICAL: Prizloncabtagene Autoleucel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute High-risk Abdominal Surgery Study - an Optimized Perioperative Course
Status: COMPLETED
Conditions: Perforated Viscus|Intestinal Obstruction
Interventions: PROCEDURE: AHA (Acute Highrisk Abdominalsurgery): Optimized Course
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety and Efficacy of Imidafenacin in Patients With Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: imidafenacin, KRP-197/ONO-8025|DRUG: imidafenacin, KRP-197/ONO-8025
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Utility of Residual Hearing in the Cochlear Implant Ear
Status: RECRUITING
Conditions: Hearing Loss, Sensorineural|Hearing Loss|Hearing Loss, Bilateral
Interventions: DEVICE: Electrocochleography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Aclaris Therapeutics, Inc. (ATI)-450 in Patients With Moderate-severe Novel Coronavirus Disease 2019 (COVID-19)
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: ATI-450|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Feeding With Ginger Extract in Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome
Interventions: DIETARY_SUPPLEMENT: ginger|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Valbenazine for the Treatment of Trichotillomania in Adults
Status: RECRUITING
Conditions: Trichotillomania (Hair-Pulling Disorder)
Interventions: DRUG: Valbenazine Oral Capsule|OTHER: Placebo Oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mind Body Balance for Pediatric Migraine
Status: RECRUITING
Conditions: Headache|Headache Disorders|Headache, Migraine|Migraine|Migraine Disorders|Migraine With Aura|Migraine Without Aura|Chronic Migraine
Interventions: BEHAVIORAL: 40 minute session|BEHAVIORAL: 20 minute session|BEHAVIORAL: home practice e-health|BEHAVIORAL: home practice handout|BEHAVIORAL: phone call
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of SPARC1104
Status: COMPLETED
Conditions: Spasticity
Interventions: DRUG: SPARC1104 modified dose regimen I|DRUG: SPARC1104 modified dose regimen II|DRUG: SPARC1104 modified dose regimen III
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Selinexor Plus Combination Chemotherapy in Treating Patients With Advanced B Cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Diffuse Large B-Cell Lymphoma|Recurrent B-Cell Non-Hodgkin Lymphoma|Recurrent Extranodal Marginal Zone Lymphoma|Recurrent Follicular Lymphoma|Recurrent Indolent Adult Non-Hodgkin Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Waldenstrom Macroglobulinemia|Refractory B-Cell Non-Hodgkin Lymphoma|Refractory Extranodal Marginal Zone Lymphoma|Refractory Follicular Lymphoma|Refractory Mantle Cell Lymphoma|Stage III Non-Hodgkin Lymphoma|Stage IV Non-Hodgkin Lymphoma|Transformed Recurrent Non-Hodgkin Lymphoma
Interventions: DRUG: Selinexor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total-Body Irradiation and Cyclophosphamide in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer and Other Diseases
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Myelodysplastic Syndromes
Interventions: DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: methotrexate|DRUG: mycophenolate mofetil|DRUG: sirolimus|DRUG: tacrolimus|OTHER: pharmacological study|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: total-body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Oral PEG 3350 on Electrolyte Balance
Status: COMPLETED
Conditions: Chronic Constipation
Interventions: DRUG: PEG 3350 plus electrolytes|DRUG: PEG 3350 without electrolytes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Metabolic Health in Patients With Diastolic Dysfunction
Status: COMPLETED
Conditions: Obesity|Heart Failure, Diastolic|Metabolic Syndrome
Interventions: BEHAVIORAL: High intensity exercise|DIETARY_SUPPLEMENT: Omega-3 fish oil|BEHAVIORAL: Yoga|DIETARY_SUPPLEMENT: olive oil capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Treatment of Manual Therapy and Therapeutic Exercise in Patients With Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain, Mechanical|Musculoskeletal Manipulations|Exercise Training
Interventions: OTHER: Exercise protocol|OTHER: Manual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-PD-1 Antibody in the Treatment of Patients With Malignant Melanoma of the Female Genital Tract
Status: UNKNOWN
Conditions: Malignant Melanoma
Interventions: DRUG: Camrelizumab for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yoga Versus Yoga Plus Mindfulness on Perceived Stress and Mindful Attention Awareness in a Chiropractic College Setting
Status: COMPLETED
Conditions: Occupational Stress
Interventions: BEHAVIORAL: Physical-Based Yoga Practice|BEHAVIORAL: Mindfulness-Based Yoga Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Turoctocog Alfa for Prophylaxis and Treatment of Bleeding Episodes in Previously Treated Chinese Patients With Haemophilia A
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A
Interventions: DRUG: turoctocog alfa|DRUG: turoctocog alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Diet and Exercise on Circadian Glycemia
Status: COMPLETED
Conditions: Glucose Intolerance
Interventions: COMBINATION_PRODUCT: Dietary manipulation (25% carbohydrate diet) and behavioral (exercise)|COMBINATION_PRODUCT: Dietary manipulation (25% carbohydrate diet) and behavioral (sedentary)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Combining Imatinib Mesylate (Gleevec) With Sorafenib in Patients With Androgen-independent Prostate Cancer (AIPC)
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Gleevec + Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of ASP1585 on Pharmacokinetics of Atorvastatin in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy|Pharmacokinetics of Atorvastatin
Interventions: DRUG: ASP1585|DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Music Therapy on Infants With Neonatal Abstinence Syndrome
Status: RECRUITING
Conditions: NAS
Interventions: BEHAVIORAL: Song of Kin|OTHER: Gato box|OTHER: Ocean disc|OTHER: Contingent singing|OTHER: Tonal Vocal holding|OTHER: Muted shaker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate How Well Ravagalimab (ABBV-323) Works and How Safe it is in Participants With Moderate to Severe Ulcerative Colitis Who Failed Prior Therapy
Status: COMPLETED
Conditions: Ulcerative Colitis (UC)
Interventions: DRUG: Ravagalimab 600 mg|DRUG: Ravagalimab 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing AZD1775 in Advanced Solid Tumors That Have a Mutation Called SETD2
Status: ACTIVE_NOT_RECRUITING
Conditions: Clear Cell Renal Cell Carcinoma|Locally Advanced Clear Cell Renal Cell Carcinoma|Locally Advanced Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm|Metastatic Renal Cell Carcinoma|Stage III Renal Cell Cancer AJCC v8|Stage IV Renal Cell Cancer AJCC v8
Interventions: DRUG: Adavosertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction Therapy With Intercalated Tyrosine Kinase Inhibitor (TKI) and Chemotherapy in NSCLC With Activating Epidermal Growth Factor Receptor (EGFR) Mutation in Stages II-IIIB
Status: TERMINATED
Conditions: Non-squamous Non-small Cell Lung Cancer Stage II|Non-squamous Non-small Cell Lung Cancer Stage IIIA|Non-squamous Non-small Cell Lung Cancer Stage IIIB|Activating EGFR Mutation|NSCLC
Interventions: DRUG: Gefitinib|DRUG: docetaxel|DRUG: cisplatin|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Continuous Positive Airway Pressure (CPAP) Treatment on Glucose Control in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Type 2 Diabetes
Interventions: DEVICE: active CPAP Therapy|DEVICE: sham CPAP therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Fexofenadine HCl 180 mg, Desloratadine 5 mg and Placebo in Suppression of Wheal and Flare Induced by Histamine
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Fexofenadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effects of tDCS on Illness Awareness in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: OTHER: Active TDCS|OTHER: Sham TDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Natural Treatments for the Management of Emotional Dysregulation in Youth With Non-verbal Learning Disability (NVLD) and/or Autism Spectrum Disorders (ASD)
Status: RECRUITING
Conditions: Non-verbal Learning Disorder|Autism Spectrum Disorder|Autism
Interventions: DRUG: Open-label Treatment with Omega-3 Fatty Acids + Inositol|DRUG: Open-label Treatment with N-acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome and Treatment Quality Study of Tolvaptan to Treat Hyponatremia in Patients With Heart Failure
Status: TERMINATED
Conditions: Heart Failure With Hyponatremia
Interventions: DRUG: Tolvaptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Management After Transnasal Transsphenoidal Surgery for Pituitary Adenomas
Status: UNKNOWN
Conditions: Pituitary Adenoma|Surgery|Pain
Interventions: DRUG: NSAID|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy With or Without Chemotherapy in Reducing Mouth Dryness in Patients With Nasopharyngeal Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Oral Complications of Radiation Therapy|Radiation Toxicity
Interventions: DRUG: cisplatin|DRUG: fluorouracil|RADIATION: Intensity modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin for the Treatment of Nonalcoholic Fatty Liver Disease (NAFLD)
Status: TERMINATED
Conditions: Fatty Liver
Interventions: DRUG: Glucophage (Metformin)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paracervical Injection for Headache in the Emergency Department
Status: TERMINATED
Conditions: Headache Disorders, Primary|Pain Management|Emergency Department
Interventions: DRUG: Paracervical injection|DRUG: prochlorperazine and diphenhydramine.(Standard Treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Safety and Effectiveness of Anlotinib for Neoadjuvant Treatment of PPGL
Status: RECRUITING
Conditions: Pheochromocytoma|Paraganglioma
Interventions: DRUG: Anlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Power Doppler Ultrasound (PDUS) to Measure Response of Secukinumab Treatment in Patients With Active Psoriatic Arthritis (PsA)
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: AIN457 (secukinumab)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Unblinded Study of TAK-438 (20 mg) for Prevention of Recurrence of Gastric or Duodenal Ulcer During Long-Term Non-Steroid Anti-Inflammatory Drug (NSAID) Therapy
Status: COMPLETED
Conditions: Gastric Ulcer|Duodenal Ulcer
Interventions: DRUG: TAK-438
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Continuous Non-invasive Blood Pressure Measurement in C-section
Status: COMPLETED
Conditions: Cesarean Delivery Affecting Newborn|Cesarean Delivery Affecting Fetus|Cesarean Section Complications
Interventions: DEVICE: ClearSight
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Ultrasound-Guided Adductor Canal Block and Surgeon-Performed Block for Pain Management After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthrosis Knee Arthroplasty Analgesia Pain Management
Interventions: PROCEDURE: Adductor canal block by surgeon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dalpiciclib Combined With Letrozole in HR+/HER2 - Gynecologic Solid Tumors
Status: RECRUITING
Conditions: Recurrent Ovarian Carcinoma
Interventions: DRUG: Dalpiciclib plus letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ocular Hygiene on Scleral Lens Wear
Status: UNKNOWN
Conditions: Scleral Contact Lenses
Interventions: DRUG: Ringers Solution|DRUG: Placebo - Concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ambulatory Liver Fat Monitoring in Patients With Non-alcoholic Fatty Liver Disease
Status: RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: BEHAVIORAL: Ambulatory monitoring of liver fat|BEHAVIORAL: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Viveve Treatment and Cryogen-Only Treatment Versus Sham Treatment for Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: Viveve - Active|DEVICE: Viveve - Cryogen-Alone|DEVICE: Viveve - Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Arrest in Residential Areas With Mobile First-responder Activation
Status: RECRUITING
Conditions: Out-Of-Hospital Cardiac Arrest
Interventions: DEVICE: Automated External Defibrillator (AED)|OTHER: Training in cardiopulmonary resuscitation and AED use|OTHER: Activation of citizen responders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Language and Lewy Body Diseases: Sentence Comprehension Problems and Modifying Noninvasive Brain Stimulation Treatment
Status: RECRUITING
Conditions: Lewy Body Disease|Healthy Aging
Interventions: DEVICE: transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Osteopathic Manipulative Treatment and Migraine Headaches
Status: UNKNOWN
Conditions: Chronic Migraine|Migraine Disorders|Headache Disorders|Headache, Migraine
Interventions: PROCEDURE: Osteopathic Manipulative Therapy (OMT)|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy and SBRT Study in Borderline Resectable Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer|Pancreatic Carcinoma Non-resectable
Interventions: DRUG: mFOLFIRINOX|BIOLOGICAL: Algenpantucel-L Immunotherapy|RADIATION: SBRT|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Adaptations to Exercise In Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Gait, Unsteady|Aerobic Exercise
Interventions: OTHER: Aerobic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Upper Trunk Block Versus Costoclavicular Block For Arthroscopic Shoulder Surgery
Status: RECRUITING
Conditions: Shoulder Pain|Phrenic Nerve Paralysis
Interventions: PROCEDURE: Upper trunk block|PROCEDURE: Costoclavicular block|PROCEDURE: Diaphragmatic function assessment|PROCEDURE: Cervical plexus blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: BTL-9000 Low Level Laser Therapy for the Waist Circumferential Reduction
Status: COMPLETED
Conditions: Circumferential Reduction|Waist Circumferential Reduction
Interventions: DEVICE: BTL-9000 LLLT|DEVICE: sham BTL-9000 LLLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study: the Antibacterial Effect of Insoluble Antibacterial Nanoparticles (IABN) Incorporated in Dental Materials for Root Canal Treatment
Status: UNKNOWN
Conditions: Endodontic Treatment|Irreversible Pulpitis|Health Pulp|Infected Pulp
Interventions: DEVICE: IABN|DEVICE: IABN|DEVICE: IABN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT