pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Nutritarian Study to Evaluate the Effectiveness of Lifestyle Changes in Chronic Disease Prevention, Especially Cancer
Status: COMPLETED
Conditions: Chronic Disease|Cancer|Cardiovascular Diseases|Diabetes Mellitus|Lifestyle-related Condition|Mental Health Wellness 1|Sleep|Nutritional and Metabolic Disease|Nutrition Related Cancer|Nutritional Imbalance|Thyroid
Interventions: OTHER: Nutritarian Diet-style
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Could Music be an Alternative to Sedation in Patients Treated Total Knee Arthroplasty With Regional Anesthesia?
Status: COMPLETED
Conditions: Anxiety|Surgery|Drug Toxicity|Anesthesia|Pain
Interventions: OTHER: Music therapy|DRUG: Sedation with midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Benefit of One Month Zopiclone Intake on Adaptative Servoventilation Compliance
Status: TERMINATED
Conditions: Sleep Apnea, Central|Ventricular Dysfunction
Interventions: DRUG: Zopiclone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Side Effects of Morphine and Hydromorphone Patient-Controlled Analgesia (PCA)
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: Morphine PCA|DRUG: Hydromorphone PCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methods of T Cell Depletion Trial (MoTD)
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Chronic Myelomonocytic Leukemia|Myelodysplastic Syndromes|Non Hodgkin Lymphoma|Hodgkin Lymphoma|Multiple Myeloma|Chronic Myelogenous Leukemia|Myelofibrosis
Interventions: DRUG: Thymoglobulin|DRUG: Cyclophosphamide|DRUG: Cyclosporine|DRUG: Sirolimus|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Empagliflozin in Chinese Female and Male Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: BI10773|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo|DRUG: BI10773
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Ph II Trial of Carboplatin and Pemetrexed With or Without AZD1775 for Untreated Lung Cancer
Status: TERMINATED
Conditions: Previously Untreated Stage IV Non-Squamous Non Small Cell Lung Cancer
Interventions: DRUG: AZD1775|DRUG: AZD1775 Matching Placebo|DRUG: pemetrexed|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biolab Zolpidem Orodispersible 1.0 mg, 1.75 mg and 3.5 mg to Treat Maintenance Insomnia Disorder.
Status: UNKNOWN
Conditions: Insomnia Disorder
Interventions: DRUG: Zolpidem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Study to Assess the Efficacy of a Dietary Ingredient in Patients With Herniated Lumbar Disc Compression
Status: COMPLETED
Conditions: Herniated Disc
Interventions: DIETARY_SUPPLEMENT: Dietary supplement GVG 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CB-5339 in Acute Myeloid Leukemia or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Acute Myeloid Leukemia, in Relapse|Myelodysplastic Syndromes
Interventions: DRUG: CB-5339
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Bioflex Crowns Endocrowns Compared to Ready-Made Zirconia Crowns on Pulpotomized Primary Molars
Status: ENROLLING_BY_INVITATION
Conditions: Primary Teeth
Interventions: PROCEDURE: treatment option for primary second molar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib in Combination With R-miniCHOP in Older Adults With Untreated Diffuse Large B-Cell Lymphoma
Status: RECRUITING
Conditions: Large B-cell Lymphoma|Diffuse Large B Cell Lymphoma
Interventions: DRUG: R-miniCHOP + Acalabrutinib|DRUG: R-miniCHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using AR Dental Care Training on Periodontal Status, Blood Sugar Control and QoL in Patients With Type 2 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus Type 2 With Periodontal Disease
Interventions: DEVICE: AR Dental Care Training System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Adjuvants for Bupivacaine in Brachial Plexus Block in Pediatrics
Status: NOT_YET_RECRUITING
Conditions: Upper Limb Injury
Interventions: DRUG: magnesium sulfate.|DRUG: clonidine.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Anti-CD19 CAR-T Cells Treating Leukemia Children
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia, Pediatric|Acute Lymphoblastic Leukemia, in Relapse|Refractory Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: Murine autologous anti-CD19 chimeric antigen receptor T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Ablation Guided by Ibutilide Use in Chronic Atrial Fibrillation
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation
Interventions: DRUG: Ibutilide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Patient-Clinic-Community Integration to Prevent Obesity Among Rural Preschool Children
Status: COMPLETED
Conditions: Pediatric Obesity|Preventive Medicine|Mentoring|Food Supply
Interventions: BEHAVIORAL: Patient Reported Outcome Well Child Visit|BEHAVIORAL: Patient Reported Outcome Well Child Visit + Food Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Thorough EKG Safety Study of TA-1790 (Avanafil)
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: moxifloxacin|DRUG: avanafil|DRUG: avanafil|DRUG: sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oseltamivir Randomised Controlled Efficacy Trial
Status: COMPLETED
Conditions: Influenza|Pneumonia|Lower Respiratory Tract Infection|Upper Respiratory Tract Infection|Viral Shedding
Interventions: DRUG: Oseltamivir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Intensity Training in Patients With Spinal and Bulbar Muscular Atrophy
Status: COMPLETED
Conditions: Spinal and Bulbar Muscular Atrophy|Healthy Subjects
Interventions: OTHER: Supervised high intensity training|OTHER: Optional training|OTHER: Control period|OTHER: Unsupervised High intensity training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transcranial Alternating Current Stimulation in Cerebral Palsy (BOOSTTACS)
Status: NOT_YET_RECRUITING
Conditions: Cerebral Palsy
Interventions: DEVICE: transcranial Alternating Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lu-DOTATATE Treatment in Patients With 68Ga-DOTATATE Somatostatin Receptor Positive Neuroendocrine Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Tumors
Interventions: DRUG: Lutetium-177 Octreotate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Long-Term Safety of MOA-728 in Participants With Opioid-Induced Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: N-methylnaltrexone bromide (MOA-728)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Booster Injection of Pentaxim™ Vaccine Administered With Dengue Vaccine in Healthy Toddlers
Status: COMPLETED
Conditions: Dengue|Dengue Hemorrhagic Fever
Interventions: BIOLOGICAL: Live, attenuated, recombinant dengue serotype 1, 2, 3, and 4 virus|BIOLOGICAL: DTaP IPV//Hib vaccine|BIOLOGICAL: Placebo|BIOLOGICAL: Measles, mumps, and rubella vaccine|BIOLOGICAL: Pneumococcal vaccine|BIOLOGICAL: Live, attenuated, recombinant dengue serotype 1, 2, 3, and 4 virus|BIOLOGICAL: DTaP IPV//Hib vaccine|BIOLOGICAL: Placebo|BIOLOGICAL: Measles, mumps, and rubella vaccine|BIOLOGICAL: Pneumococcal vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Relapse Prevention for Suicidal Dually Diagnosed Youths
Status: COMPLETED
Conditions: Suicide, Attempted|Suicide, Ideation|Depression|Substance Abuse
Interventions: BEHAVIORAL: CBT-RP (relapse prevention) + Enhanced TAU|BEHAVIORAL: Enhanced TAU Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of 2-Week Nightly Moderate Hypoxia on Glucose Tolerance in Individuals With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DEVICE: Hypoxico Altitude Training Systems
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cholecalciferol Supplementation on Disease Activity and Quality of Life of Systemic Lupus Erythematosus Patients .
Status: COMPLETED
Conditions: Lupus Erythematosus, Systemic|Cholecalciferol Supplementation|Disease Activity|Quality of Life
Interventions: DRUG: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: INvestigating the Value of Early Sleep Therapy
Status: NOT_YET_RECRUITING
Conditions: Acute Insomnia (Disorder)
Interventions: BEHAVIORAL: Sleep Restriction Therapy (SRT)|BEHAVIORAL: Sleep Hygiene Education (SHE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Innate Immunity Stimulation Via TLR9 in Early AD
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Alzheimer Dementia
Interventions: DRUG: CpG1018|DRUG: CpG1018|DRUG: CpG1018|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ToAST:Investigating the Effect of Bronchial Thermoplasty on Cough in Patients With Severe Asthma
Status: UNKNOWN
Conditions: Asthma Chronic, Cough
Interventions: OTHER: Inhaled capsaicin cough challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Nitrate Supplementation on Blood Pressure and Microvascular Function of Resistant Hypertensive Patients
Status: RECRUITING
Conditions: Arterial Hypertension|Resistant Hypertension|Microvascular Function|Nitrate Supplementation
Interventions: DIETARY_SUPPLEMENT: Beetroot extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain After PRP Revascularization and Endodontic Treatment of Non-vital Mandibular Molars With Apical Periodontitis
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: PROCEDURE: Platelet rich plasma PRP|PROCEDURE: root canal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin A for Herpes Labialis
Status: TERMINATED
Conditions: Herpes Labialis
Interventions: DRUG: onabotulinumtoxinA|OTHER: Bacteriostatic normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect Of Modafinil And Pioglitazone On The Pharmacokinetics Of Palbociclib (PD-0332991)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Palbociclib alone|DRUG: Palbociclib plus Modafinil|DRUG: Palbociclib alone|DRUG: Palbociclib plus pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chinese Herbal Medicine Formula Combined With Inhaled Corticosteroids for the Treatment of Mild to Persistent Asthma in Children
Status: UNKNOWN
Conditions: Childhood Asthma
Interventions: DRUG: CM (Ma-Hsing-Kan-Shih-Tang in combination with Liu-Jun-Zi-Tang)|DRUG: 10% CM (Ma-Hsing-Kan-Shih-Tang in combination with Liu-Jun-Zi-Tang)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Same-day Cervical Preparation Before Dilation and Evacuation
Status: COMPLETED
Conditions: Cervical Dilation Prior to Dilation and Evacuation
Interventions: DEVICE: Same-Day Dilapan-S|DEVICE: Overnight Dilapan-S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Erlotinib Combined With Gemcitabine in Treating Patients With Newly Diagnosed Locally Advanced or Metastatic Pancreatic Cancer or Other Solid Tumors
Status: COMPLETED
Conditions: Pancreatic Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: erlotinib hydrochloride|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of GlaxoSmithkline (GSK) Biologicals' Investigational Vaccine GSK2838504A When Administered to Chronic Obstructive Pulmonary Disease (COPD) Patients With Persistent Airflow Obstruction.
Status: COMPLETED
Conditions: Respiratory Disorders
Interventions: BIOLOGICAL: NTHi-10-AS01E|DRUG: NaCl Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acalabrutinib Maintenance for the Treatment of Patients With Large B-cell Lymphoma
Status: RECRUITING
Conditions: Diffuse Large B-Cell Lymphoma|High-grade B-cell Lymphoma|Transformed Lymphoma|Secondary Central Nervous System Lymphoma
Interventions: DRUG: Acalabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-Expandable Esophageal Radiation Stent:a Randomized Controlled Trial in Patients With Advanced Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: PROCEDURE: Esophageal stent placement|PROCEDURE: dysphagia scores|PROCEDURE: complications of therapy|PROCEDURE: survival time of therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Mini Implant Facilitated Micro-osteoperforations on the Alignment of Mandibular Anterior Crowding
Status: COMPLETED
Conditions: Tooth Position Anomalies
Interventions: PROCEDURE: Micro-osteoperforation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Simvastatin Withdrawal on Ocular Endothelial Function
Status: WITHDRAWN
Conditions: Healthy
Interventions: DEVICE: Dynamic Vessel Analyzer (DVA)|DEVICE: Laser Doppler Velocimetry (LDV)|DRUG: Simvastatin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Azilsartan Medoxomil in Participants With Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Azilsartan medoxomil and olmesartan|DRUG: Azilsartan medoxomil and olmesartan|DRUG: Azilsartan medoxomil and olmesartan|DRUG: Olmesartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Systemic Pharmacokinetics of Levobupivacaine and Ropivacaine During Continuous Epidural Infusion
Status: COMPLETED
Conditions: Anesthesia|Surgery
Interventions: DRUG: local anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Vutiglabridin in Early Parkinson's Disease Patients
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DRUG: Vutiglabridin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation Supports for Improving Identification and Delivery of School-based Mental Health Supports for Middle Schools Students
Status: RECRUITING
Conditions: Mental Health Issue
Interventions: BEHAVIORAL: EIS Only|BEHAVIORAL: EIS + ECHO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of 24-week Dietary Intake of Food Supplements on Hair
Status: ENROLLING_BY_INVITATION
Conditions: Hair Thinning|Hair Loss
Interventions: DIETARY_SUPPLEMENT: Investigational product 1 (CPMSM)|DIETARY_SUPPLEMENT: Investigational product 2 (HC+)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dapagliflozin on VT in Patients With Heart Failure.
Status: NOT_YET_RECRUITING
Conditions: Heart Failure
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Positioning the Trunk and Upper Limb to Improve the Coordination of the Hand Movement After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: PROCEDURE: hand motor coordination in a sitting positin|PROCEDURE: hand motor coordination in a supine position with the upper extremity positioned perpendicularly to the trunk|PROCEDURE: hand motor coordination in a supine position with adduction in the humeral joint, elbow flexion in the intermediate position
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Study of the BioVac Direct Suction Device in Upper Gastrointestinal Bleeding
Status: TERMINATED
Conditions: Gastrointestinal Hemorrhage
Interventions: DEVICE: BioVac Direct Suction Device|DEVICE: Standard Endoscopy Suction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Cardioprotective Benefits of Carvedilol-CR or Valsartan Added to Lisinopril
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Carvedilol CR|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation and Expansion Study of SYH2043 in Patients With Advanced Malignant Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Malignant Tumors
Interventions: DRUG: SYH2043
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Natural History of Severe Allergic Inflammation and Reactions
Status: COMPLETED
Conditions: PGM3 Deficiency|Eosinophilic and/or Atopic Dermatitis|OSMR Deficiency|Primary Localized Cutaneous Amyloidosis|Hereditary Alpha-tryptasemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Food Effect on the Eradication Rate of H. Pylori With Triple Therapy With Esomeprazole
Status: WITHDRAWN
Conditions: Helicobacter Pylori Infection
Interventions: OTHER: Food effect|DRUG: Esomeprazole|DRUG: Amoxicillin|DRUG: Clarythromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autopsy and Photon Counting Computed Tomography to Evaluate Thromboses Related to Central Venous Catheters
Status: NOT_YET_RECRUITING
Conditions: Central Venous Catheter Thrombosis
Interventions: DIAGNOSTIC_TEST: Diseased patients with an indwelling central venous catheter who is referred to autopsy|RADIATION: Living patients with an indwelling central venous catheter referred to a CT scan without iv contrast
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating XPERIENCE™ Advanced Surgical Irrigation
Status: RECRUITING
Conditions: Hip Osteoarthritis|Hip Arthritis|Knee Osteoarthritis|Knee Arthritis
Interventions: DEVICE: XPERIENCE Advanced Surgical Irrigation|DEVICE: Dilute Betadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Image-guided Identification of Response to Neoadjuvant Chemoradiotherapy in Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Cancer|Esophageal Adenocarcinoma|Esophageal Squamous Cell Carcinoma|Esophageal Neoplasms
Interventions: DIAGNOSTIC_TEST: MRI|DIAGNOSTIC_TEST: PET-CT|DIAGNOSTIC_TEST: Endoscopy|DIAGNOSTIC_TEST: Blood samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bariatric Surgeries and Glucose Homeostasis During a Mixed Meal Test
Status: COMPLETED
Conditions: Obesity
Interventions: PROCEDURE: Roux-en-Y-gastric bypass|PROCEDURE: laparoscopic adjustable gastric banding|PROCEDURE: laparoscopic sleeve gastrectomy|OTHER: diet treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Self-Management Skills Training Given to Nursing Students According to Peer Education Module on Problematic Internet Use and Academic Procrastination Behavior
Status: COMPLETED
Conditions: Problem Behavior|Problematic Internet Use|Academic Procrastination Behavior
Interventions: OTHER: Self Management Skills Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Randomized Controlled Trial to Compare the Glycemic Control, With or Without the Connected Solution, of Adult Type 2 Diabetic Participants on Basal Insulin in Taiwan
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: COMBINATION_PRODUCT: Connected Solution with H2S app which connects with blood glucose meter (BGM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors
Status: RECRUITING
Conditions: Clear Cell Renal Cell Carcinoma|Solid Tumors
Interventions: DRUG: AB521|DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Epcoritamab in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter's Syndrome
Status: RECRUITING
Conditions: Relapsed/Refractory Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma|Richter's Syndrome
Interventions: BIOLOGICAL: Epcoritamab|BIOLOGICAL: Epcoritamab|DRUG: rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone|DRUG: Venetoclax|BIOLOGICAL: Epcoritamab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pilates-based Therapeutic Exercises on the Postural Control
Status: COMPLETED
Conditions: Motor Disorders
Interventions: OTHER: Pelvis Retroverted|OTHER: Pelvis in Neutral Position|OTHER: Aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Effects of Treadmill Training With Post-stroke Functional Electrical Stimulation
Status: UNKNOWN
Conditions: Stroke
Interventions: OTHER: treadmill gait training with gait facilitators|OTHER: treadmill gait training not-associated with gait facilitators
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-IRA Functional Evaluation With AccuFFRangio in NSTE-ACS
Status: UNKNOWN
Conditions: Non ST Segment Elevation Acute Coronary Syndrome|Coronary Artery Disease|Percutaneous Coronary Intervention
Interventions: OTHER: AccuFFRangio-guided strategy|OTHER: Angiography-guided strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Marizomib for Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial, and Spinal Cord Ependymoma
Status: TERMINATED
Conditions: Anaplastic Ependymoma|Ependymoma|Ependymomas
Interventions: DRUG: Marizomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remission Through Early Monitored Insulin Therapy - Duration Month
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Glargine|DRUG: Lispro|DEVICE: Dexcom G6
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Vinorelbine Plus Capecitabine Combined With Trastuzumab for HER2 Positive Patients Following Neoadjuvant Chemotherapy
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Vinorelbine|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Silver Diamine Fluoride Versus Sodium Fluoride Varnish With Parental Behavior Modification in Arresting Early Childhood Caries
Status: COMPLETED
Conditions: Early Childhood Caries
Interventions: DRUG: Sodium Fluoride Varnish (5%)|BEHAVIORAL: Motivational Interviewing|DRUG: SDF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of ON-tDCS on Memory Function Improvement and Related Circuits in Stable Depression Patients
Status: RECRUITING
Conditions: Depression
Interventions: DEVICE: Active ON-tDCS|DEVICE: Sham ON-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Assessing the Effectiveness of Use of Guided Imagery for Treatment of Pain and Symptom Management in Women With Post-mastectomy Pain Syndrome
Status: COMPLETED
Conditions: Pain Syndrome|Pain|Symptom Management
Interventions: OTHER: The Intervention Group|OTHER: The Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Simeox Airway Clearance Therapy in Children With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis in Children|Airway Clearance Impairment
Interventions: DEVICE: Simeox|OTHER: CCPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute and Chronic Toxicity of Some Synthetic Cannabinoids in Assiut Psychiatric Hospitals
Status: UNKNOWN
Conditions: Epidemiologic Data of Some Synthetic Cannibinoids Toxicity in Patients Presenting at Assiut University Hospital, Psychiatric Hospital of Ministry of Health)|Proportion of Acute and Chronic Abusers of Synthetic Cannibinoids Among Cases of Illicit Drugs Abuser in Studied Sites
Interventions: BEHAVIORAL: causes of abuse synthetic cannibinoids
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pulses of Vincristine and Dexamethasone in BFM Protocols for Children With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: vincristine|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of PC945 on Aspergillus Fumigatus Lung Infection in Patients With Cystic Fibrosis
Status: TERMINATED
Conditions: Aspergillosis|Cystic Fibrosis
Interventions: DRUG: PC945
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Segmental Spinal Anesthesia for Small-incision Cholecystectomy in a Field Hospital
Status: COMPLETED
Conditions: Gall Stones (& [Calculus - Gall Bladder])|Anesthesia
Interventions: PROCEDURE: segmental spinal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of GlaxoSmithKline Biologicals' GSK2202083A Vaccine in Healthy Infants at 3, 5 and 11 Months of Age.
Status: TERMINATED
Conditions: Tetanus|Poliomyelitis|Neisseria Meningitidis|Haemophilus Influenzae Type b|Diphtheria|Acellular Pertussis|Hepatitis B
Interventions: BIOLOGICAL: GSK2202083A vaccine|BIOLOGICAL: Infanrix hexa|BIOLOGICAL: Menjugate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intervention Mapping to Adapt a Mindfulness-based Intervention for Adults With Diabetes and Emotional Distress
Status: COMPLETED
Conditions: Type 2 Diabetes|Stress
Interventions: BEHAVIORAL: Integrated MBSR/DSME intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AQUACEL® Ag+ Extra™ and Cutimed™ Sorbact® Dressing in the Management of Venous Leg Ulcers Over a 12-week Period
Status: COMPLETED
Conditions: Venous Leg Ulcer|Diabetic Foot
Interventions: DEVICE: AQUACEL® Ag+ Extra™|DEVICE: Cutimed® Sorbact®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zepatier For Treatment Of Hepatitis C-Negative Patients Who Receive Heart Transplants From Hepatitis C-Positive Donors (HCV)
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Zepatier
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PAD. ICORG 05-01, V11
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: Bortezomib|DRUG: Doxorubicin|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Potential Usefulness of 18F-AlF-FAPI PET/CT in Patients With Gastrointestinal Tumors and Compared With 18F-FDG PET/CT
Status: UNKNOWN
Conditions: Gastric Cancer|Pancreatic Cancer|Liver Cancer
Interventions: DIAGNOSTIC_TEST: 18F-FDG, 18F-AlF-FAPI PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Role of Epithelial Barrier Integrity in Biologic Treatment Response of Severe Asthmatics With/Out Chronic Rhinosinusitis With Nasal Polyps (CRSwNP).
Status: RECRUITING
Conditions: Severe Eosinophilic Asthma w/wo CRSwNP
Interventions: DRUG: Mepolizumab 100 MG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiation Stent Versus Self-expanding Metallic Stents (SEMS) for Palliative Treatment of Malignant Biliary Stricture
Status: COMPLETED
Conditions: Cholangiocellular Carcinoma|Pancreatic Cancer|Gallbladder Cancer|Metastatic Carcinoma
Interventions: DEVICE: self-expandable 125I radioactive seeds-loaded-stent|DEVICE: self-expandable biliary nitinol alloys stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain Intensity Associated With the Use of Different Nickel Titanium Instrumentation Systems
Status: COMPLETED
Conditions: Pain, Postoperative|Endodontically Treated Teeth
Interventions: DEVICE: Group 1: single file rotary motion|DEVICE: Group 2: multiple file rotary motion|DEVICE: Group 3: single file reciprocal motion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Assessment of Cognitive Function After Surgery in Two Types of Anesthesia in Patients Operated for Breast Cancer
Status: COMPLETED
Conditions: Patients With Breast Cancer and Breast Surgery Requiring
Interventions: OTHER: hypnosedation|OTHER: general anesthésia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized,Double Blind, Placebo Controlled Study to Assess Efficacy,Safety and Tolerability of BGG492 in Migraine Prevention
Status: WITHDRAWN
Conditions: Patients With Migraine Equal of /More Than 3 and Equal of/ Less Than 12 Migraine Attacks/4 Weeks for Each of the Last 6 Months Preceding the Screening
Interventions: DRUG: BGG492|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pixantrone + Rituximab With Gemcitabine + Rituximab in Patients With Aggressive B-cell Non-Hodgkin Lymphoma or Follicular Grade 3 Lymphoma Who Have Relapsed After Therapy and Are Not Eligible for Stem Cell Transplant
Status: COMPLETED
Conditions: Diffuse Large B-cell Lymphoma|de Novo DLBCL|DLBCL Transformed From Indolent Lymphoma|Follicular Grade 3 Lymphoma
Interventions: DRUG: Pixantrone + Rituximab|DRUG: Gemcitabine + Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fuzhenghuayu for Patients With PBC Who Had An Inadequate Response to Ursodeoxycholic Acid
Status: UNKNOWN
Conditions: Primary Biliary Cirrhosis
Interventions: DRUG: Fuzhenghuayu|DRUG: UDCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Intratumoral MVR-C5252 (C5252) in Patients With Recurrent or Progressive Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor|Glioblastoma|Glioblastoma Multiforme|Glioblastoma Multiforme of Brain
Interventions: BIOLOGICAL: C5252
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasability and Clinical Impact Study of Non Pharmacological Interventions in Management of Chronic Pain
Status: COMPLETED
Conditions: Chronic Pain|Slackline|Mindfulness|Adapted Physical Activity|Self-hypnosis|Qi Gong
Interventions: OTHER: a systematic proposal for non pharmacological interventions targeting the subject's empowerment among slackline, mindfulness, adapted physical activity, self-hypnosis, and Qi Gong
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Intraoperative Intravenous Lidocaine Infusion and Transversus Abdominis Plane (TAP) Block for Post-operative Analgesia Following Laproscopic Cholecystectomy
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: Lidocaine IV|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ginkgo Leaf Extract and Armillariella Mellea Powder Oral Solution for the Treatment of Motoric Cognitive Risk Syndrome
Status: RECRUITING
Conditions: Motoric Cognitive Risk Syndrome|Mild Cognitive Impairment|Aging|Locomotive Syndrome
Interventions: DRUG: Ginkgo Leaf Extract and Armillariella Mellea Powder Oral Solution|DRUG: Simulation of Ginkgo Leaf Extract and Armillariella Mellea Powder Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Bioactive Bulk Fill Composite Versus High Viscosity Glass Ionomer Restorations for Carious Lesions
Status: UNKNOWN
Conditions: Secondary Dental Caries
Interventions: OTHER: Predicta Bioactive bulk fil composite restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluating Impact of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Parathyroidectomy
Status: RECRUITING
Conditions: Parathyroid Adenoma|Parathyroid Neoplasms|Parathyroid Cancer|Hypercalcemia|Primary Hyperparathyroidism
Interventions: DEVICE: PTeye
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Exercise Intervention Prior to CRS-HIPEC: Feasibility & Impact
Status: TERMINATED
Conditions: Colon Cancer|Ovarian Cancer|GI Cancer|Gynecologic Cancer
Interventions: BEHAVIORAL: Home-based Exercise Program Prior to CRS-HIPEC|BEHAVIORAL: Exercise Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypoalgesic Effect of Electrical Current and Cervical Manipulation
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: Application of TENS|DEVICE: CJM|DEVICE: Placebo TENS|DEVICE: Placebo CJM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Intermittent Theta Burst Stimulation in MCI and Early AD
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Alzheimer Disease|Cognitive Decline
Interventions: DEVICE: intermittent theta burst stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of EEG With Respect to the Change of Depth of Anesthesia During General Anesthesia
Status: UNKNOWN
Conditions: Anesthesia
Interventions: DEVICE: Electroencephalography|DRUG: Propofol|DRUG: Rocuronium bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluate the Effects of Patupilone on the Pharmacokinetics of Midazolam and Omeprazole in Patients With Advanced Malignancies (Extension)
Status: WITHDRAWN
Conditions: Solid Tumors
Interventions: DRUG: Patupilone|DRUG: Patupilone + Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Senicapoc in Alzheimer's Disease
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Alzheimer Disease
Interventions: DRUG: Senicapoc|OTHER: Placebo Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Depletion of Serum Amyloid P Component to Enhance the Immune Response to DNA Vaccination
Status: COMPLETED
Conditions: HIV
Interventions: BIOLOGICAL: pSG2.HIVconsv DNA vaccine|BIOLOGICAL: ChAdV63.HIVconsv booster vaccine|BIOLOGICAL: MVA.HIVconsv booster vaccine|DRUG: CPHPC|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Outcome Following Antidepressant Treatment on Possible Endo-Phenotypes for Major Depression
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Escitalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Accountability for Cancer Care Through Undoing Racism and Equity
Status: COMPLETED
Conditions: Breast Cancer|Lung Cancer
Interventions: OTHER: ACCURE Navigator|OTHER: Usual Care by Cancer Center Care Team
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluating an Intervention to Prevent Overdoses in Rural and Urban Counties
Status: RECRUITING
Conditions: Opiate Overdose|Fentanyl Overdose|Harm Reduction
Interventions: BEHAVIORAL: Fentanyl Test Strips
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Evaluate Safety & Immunogenicity of DelNS1-2019-nCoV-RBD-OPT1 for COVID-19 in Healthy Adults Received 2 Doses of BNT162b2
Status: UNKNOWN
Conditions: Covid19
Interventions: BIOLOGICAL: DelNS1-2019-nCoV-RBD-OPT1|BIOLOGICAL: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Bimatoprost 0.03% in Patients Who Are Low-Responders to Latanoprost
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Bimatoprost 0.03%, Latanoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Measuring Dietary Iron Absorption From Edible Insects and Assessing the Effect of Chitin Content on Iron Bioavailability (Study 2)
Status: UNKNOWN
Conditions: Iron-deficiency
Interventions: OTHER: Bread and butter|OTHER: X.gideon|OTHER: X.gideon with ascorbic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: An Open-Label Exploratory Study of ABBV-CLS-7262 Subjects With Vanishing White Matter Disease
Status: RECRUITING
Conditions: Vanishing White Matter Disease
Interventions: DRUG: ABBV-CLS-7262
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Action Feedback and Engagement (SAFE) Loop
Status: ENROLLING_BY_INVITATION
Conditions: Medication Errors|Patient Safety
Interventions: BEHAVIORAL: Safety Action Feedback and Engagement (SAFE) Loop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: VNS Therapy Automatic Magnet Mode Outcomes Study in Epilepsy Patients Exhibiting Ictal Tachycardia (E-37)
Status: COMPLETED
Conditions: Epilepsy
Interventions: DEVICE: M106 VNS Therapy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computerized DBT Skills Training for Suicidal and Heavy Episodic Drinkers
Status: COMPLETED
Conditions: Suicidal Ideation|Alcohol Drinking
Interventions: BEHAVIORAL: Computerized Dialectical Behavior Therapy Skills Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Piloting Acute Care to Primary Care Linkage of Safety Net Patients
Status: TERMINATED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Motivational Interviewing|DRUG: FDA-Approved Anti-Anxiety Medications|BEHAVIORAL: Standard Care Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of GMX1777 in Combination With Temozolomide for the Treatment of Metastatic Melanoma
Status: TERMINATED
Conditions: Metastatic Melanoma
Interventions: DRUG: Obatoclax Mesylate|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT