pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Characterizing the Inflammation Around Dental Implants
Status: ENROLLING_BY_INVITATION
Conditions: Peri-Implantitis|Peri-implant Mucositis|Implant Site Reaction|Implant Site Infection|Hypersensitivity|Implant Site Rash|Implant Infection
Interventions: DIAGNOSTIC_TEST: Clinical examination of a dental implant|DIAGNOSTIC_TEST: Radiological Examination|DIAGNOSTIC_TEST: Peri-implant crevicular fluid sample collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Matched Unrelated vs. Haploidentical Donor for Allogeneic Stem Cell Transplantation in Patients With Acute Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia in Remission|Acute Lymphoblastic Leukemia in Remission|Myelodysplastic Syndromes
Interventions: DRUG: Allogeneic Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAXUS PERSEUS Small Vessel
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Percutaneous Coronary Intervention (PCI) with paclitaxel-eluting stent (TAXUS Element) implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vesical Imaging-Reporting and Data System (VI-RADS) Followed by Photodynamic Trans-urethral Resection of Bladder Tumours (PDD-TURBT) to Avoid Secondary Resections (Re-TURBT) in Non-Muscle Invasive Bladder Cancers (NMIBCs)
Status: NOT_YET_RECRUITING
Conditions: Non-muscle-invasive Bladder Cancer|Non-Muscle Invasive Bladder Urothelial Carcinoma|High Risk Non-Muscle Invasive Bladder Urothelial Carcinoma
Interventions: DRUG: PDD-TURBT with hexaminolevulinate (Hexvix®)|DEVICE: Power Led Saphira (TM) from KARL STORZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Immunogenicity Trial of a Respiratory Syncytial Virus Vaccine, LYB005 in Healthy Adults
Status: NOT_YET_RECRUITING
Conditions: Respiratory Syncytial Virus (RSV)|RSV Infection
Interventions: BIOLOGICAL: LYB005 low dose without adjuvant|BIOLOGICAL: LYB005 middle dose without adjuvant|BIOLOGICAL: LYB005 high dose without adjuvant|BIOLOGICAL: LYB005 low dose with adjuvant|BIOLOGICAL: LYB005 middle dose with adjuvant|BIOLOGICAL: LYB005 high dose with adjuvant|BIOLOGICAL: Placebo|BIOLOGICAL: Positive control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Project INSPIRE: INtervention Support Groups: Peers Inspiring Resilience and Empowerment
Status: TERMINATED
Conditions: Domestic Violence
Interventions: BEHAVIORAL: (INSPIRE) INtervention Support groups: Peers Inspiring Resilience and Empowerment.|BEHAVIORAL: Traditional Domestic Violence Support Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Positive Psychological Group Psychotherapy and Auricular Acupressure on Withdrawal Symptoms
Status: RECRUITING
Conditions: Gambling
Interventions: BEHAVIORAL: group counseling|DEVICE: auricular acupressure|DEVICE: placebo acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Use of Zarzio® in Post-autologous Stem Cell Transplantation Procedure
Status: COMPLETED
Conditions: Multiple Myeloma|Non-hodgkin Lymphoma|Hodgkin Lymphoma
Interventions: DRUG: Filgrastim Prefilled Syringe [Zarzio®]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetic Interaction Study of Dapoxetine 30mg and Mirodenafil 100mg
Status: COMPLETED
Conditions: Drug Interaction Potentiation
Interventions: DRUG: Dapoxetine 30mg|DRUG: Mirodenafil 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Clinical Trial to Evaluate the Immunogenicity and Safety of SCTV01E in Population Aged ≥18 Years Previously Fully Vaccinated With mRNA COVID-19 Vaccine
Status: UNKNOWN
Conditions: COVID-19|Sars-CoV-2 Infection
Interventions: BIOLOGICAL: SCTV01E|BIOLOGICAL: Comirnaty|BIOLOGICAL: SCTV01E|BIOLOGICAL: Comirnaty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Auditory and Visual Noise as Possible Non-pharmacological Treatment of ADHD in School Children
Status: RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder|Neurodevelopmental Disorders
Interventions: DEVICE: Auditory noise stimulation|DEVICE: Visual noise stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROMISS: Simvastatin Prevents the Contrast Induced Acute Renal Failure in Patients With Renal Insufficiency Undergoing Coronary Angiography
Status: COMPLETED
Conditions: Kidney Failure
Interventions: DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Expressive Writing for the Management of Stress in Cancer Survivors
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: BEHAVIORAL: Behavioral Intervention|BEHAVIORAL: Behavioral Intervention|BEHAVIORAL: Behavioral Intervention|BEHAVIORAL: Behavioral Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using Adalimumab Serum Concentration to Choose a Subsequent Biological DMARD in Rheumatoid Arthritis Patients Failing Adalimumab Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DIAGNOSTIC_TEST: Adalimumab trough concentration|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MethaCholine Bronchoprovocation Study (MeCIS)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: fluticasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Combination Therapies to Reduce Carriage of SARS-Cov-2 and Improve Outcome of COVID-19 in Ivory Coast: a Phase Randomized IIb Trial
Status: UNKNOWN
Conditions: COVID-19|COVID-19 Drug Treatment|Severe Acute Respiratory Syndrome Coronavirus 2
Interventions: DRUG: Lopinavir/Ritonavir 200 MG-50 MG Oral Tablet|DRUG: Telmisartan 40Mg Oral Tablet|DRUG: Atorvastatin 20 Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study in Relapsing-remitting Multiple Sclerosis (RRMS) Patients Receiving Betaferon or Rebif
Status: COMPLETED
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: DRUG: Betaferon/Betaseron|DRUG: Rebif|DRUG: Betaferon/Betaseron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects Of KC On Exclusively Breastfeeding And Baby's Growth And Development According To Attachment Theory
Status: COMPLETED
Conditions: Breastfeeding, Exclusive|Growth Acceleration|Development, Infant|Attachment
Interventions: OTHER: Kangaroo Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Low-Level Laser Therapy in Carpal Tunnel Syndrome
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: treatment with low-level laser therapy|DEVICE: treatment with conventional light diodes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Borderline Resectable Pancreatic Cancer: Gemcitabine/Docetaxel and Oxaliplatin Based Chemo/RT
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine, Docetaxel, 5FU, Oxaliplatin|BIOLOGICAL: Alpha-interferon|RADIATION: Abdominal/pelvic radiation therapy|PROCEDURE: Pancreaticoduodenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Portable Colposcopy and HPV Genotypes Among HIV+ Women
Status: TERMINATED
Conditions: Cervical Cancer|Human Papillomavirus|Human Immunodeficiency Virus
Interventions: DEVICE: Portable colposcopy (Cerviscope)|DEVICE: Conventional colposcopy (Wallach Zoomscope)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Accuracy of Needle Placement Into The Subacromial Space of The Shoulder
Status: COMPLETED
Conditions: Rotator Cuff Tendonitis
Interventions: PROCEDURE: Injection of Subacromial Bursa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of CWP-0403 Compared to Sitagliptin in Patients With Type 2 Diabetes Mellitus Insufficiently Controlled With Metformin Alone
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Anagliptin|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Active Idiopathic Inflammatory Myopathy
Status: ENROLLING_BY_INVITATION
Conditions: Myositis|Active Idiopathic Inflammatory Myopathy|Dermatomyositis|Polymyositis|Immune-Mediated Necrotizing Myopathy|Antisynthetase Syndrome
Interventions: BIOLOGICAL: EFG PH20 SC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of ThermaWedge™ Device and Achilles Tendon Stretching for the Treatment of Plantar Fasciopathy
Status: COMPLETED
Conditions: Plantar Fasciitis|Plantar Fasciopathy
Interventions: DEVICE: ThermaWedge TM|OTHER: Achilles Tendon Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Artemisia Dracunculus on Glucose Intolerance, Insulin Sensitivity and Insulin Secretion
Status: COMPLETED
Conditions: Glucose Intolerance
Interventions: DIETARY_SUPPLEMENT: Artemisia dracunculus|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Avelumab With or Without Cetuximab in Treating Patients With Advanced Skin Squamous Cell Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Skin Squamous Cell Carcinoma|Metastatic Skin Cancer
Interventions: DRUG: Avelumab|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of IV VIS410 Plus Oseltamivir Versus Oseltamivir in Hospitalized Adults With Influenza A
Status: COMPLETED
Conditions: Influenza A
Interventions: DRUG: Low dose of VIS410|DRUG: High dose of VIS410|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Precision Care for Major Depressive Disorder
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Disorder|Depression|Depressive Disorder, Major
Interventions: DRUG: Pramipexole|DRUG: Methylphenidate|DRUG: Phenelzine|BEHAVIORAL: Mindfulness-based Stress Sensitivity Therapy (MBSST)|BEHAVIORAL: Complicated Grief Treatment (CGT)|OTHER: Care as usual (CAU) plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using E-Nose Technology to Measure Response to Treatment in People With Malignant Pleural Mesothelioma
Status: RECRUITING
Conditions: Malignant Pleural Mesothelioma
Interventions: DIAGNOSTIC_TEST: E-Nose testing|DIAGNOSTIC_TEST: Research blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)
Status: NOT_YET_RECRUITING
Conditions: Myelodysplastic Syndrome
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|DRUG: Decitabine and Cedazuridine|DRUG: Enasidenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Prosthetic Feet for People With Syme's Amputation (XF Symes Study)
Status: COMPLETED
Conditions: Amputation|Artificial Limb
Interventions: DEVICE: Crossover foot|DEVICE: Energy Storing Foot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Curcumin in Paclitaxel Induced PN
Status: NOT_YET_RECRUITING
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: DIETARY_SUPPLEMENT: Curcumin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 1 Safety Study of Single and Multi-Dose Topically Applied OLT1177 Gel in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: OLT1177 Gel|DRUG: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adoptive Cell Transfer of Autologous Tumor Infiltrating Lymphocytes and High-Dose Interleukin 2 in Select Solid Tumors
Status: RECRUITING
Conditions: Metastatic Melanoma|Locally Advanced Refractory/Recurrent Melanoma|Metastatic Head and Neck Cancer|Locally Advanced Refractory/Recurrent Head and Neck Cancer
Interventions: BIOLOGICAL: Autologous Tumor Infiltrating Lymphocytes|BIOLOGICAL: High-Dose Interleukin 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Effectiveness of Liquid Certolizumab Pegol in the Treatment of Signs and Symptoms of Rheumatoid Arthritis and in Prevention of Joint Damage in Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Certolizumab Pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Dose of Antivenom for Daboia Siamensis Envenomings
Status: SUSPENDED
Conditions: Daboia Siamensis Envenoming
Interventions: BIOLOGICAL: lyophilized BPI viper antivenom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Fecal Microbiota Transfer on Progression of Parkinson Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease
Interventions: BIOLOGICAL: Fecal Microbiota Transfer provided by Human Biome Institute
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Gum Health Gel in Post Extraction Sockets
Status: RECRUITING
Conditions: Impacted Third Molar Tooth
Interventions: PROCEDURE: Gum Health gel|PROCEDURE: Gel foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Reanimator Muller in Patients With Chest Tube
Status: UNKNOWN
Conditions: Mechanical Ventilation Complication
Interventions: DEVICE: Reanimator group|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Cross-over Study for Normal Pressure Hydrocephalus
Status: COMPLETED
Conditions: Normal Pressure Hydrocephalus
Interventions: DEVICE: MIETHKE proGAV® / MIETHKE proSA®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cleanoze® Irrigation Device With Powder Preparation Versus Conventional Irrigation Method for Chronic Rhinitis
Status: COMPLETED
Conditions: Rhinitis
Interventions: DRUG: Cleanoze®|DRUG: Saline (Syringe irrigation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rRp450-Phase I Trial in Liver Metastases and Primary Liver Tumors
Status: TERMINATED
Conditions: Liver Metastases|Primary Liver Cancers
Interventions: BIOLOGICAL: administration of rRp450 into the hepatic artery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Galeo® in Patients With Postprandial Distress Syndrome Subtype in Functional Dyspepsia
Status: COMPLETED
Conditions: Dyspepsia
Interventions: DRUG: Dihydroxydibutylether group|DRUG: Control group placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Identifying and Addressing Barriers to Retention in the Cervical Cancer Treatment Cascade Among Women With HIV in South Africa: Part 2
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer|Hiv
Interventions: BEHAVIORAL: Retention in cervical cancer care intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sodium Bicarbonate on Prevention of Acute Kidney Injury in High Risk Patients Undergoing Off-pump Coronary Artery Bypass (OPCAB)
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: sodium bicarbonate|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A First-in-Human Study to Evaluate JCXH-105, an srRNA-based Herpes Zoster Vaccine
Status: ACTIVE_NOT_RECRUITING
Conditions: Herpes Zoster (HZ)|Shingles|Infectious Disease
Interventions: BIOLOGICAL: JCXH-105|BIOLOGICAL: Active Control (Shingrix)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Adductor-canal-block Versus Peri-articular Infiltration on Outcome After Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Osteoarthritis,Knee
Interventions: DRUG: single adductor-canal-block|DRUG: periarticular infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3454738 in the Treatment of Adult Participants With Moderate-to-Severe Atopic Dermatitis
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: LY3454738|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dilated Versus Non-Dilated Wavefront Corrections for Patients With Down Syndrome
Status: RECRUITING
Conditions: Down Syndrome|Refractive Errors
Interventions: DEVICE: Dilated Refraction|DEVICE: Non-Dilated Refraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Therapy Selection Based on Tumor Tissue Kinase Activity Profiles for Patients With Advanced Solid Malignancies, an Exploratory Study
Status: TERMINATED
Conditions: Advanced Solid Tumors|Inoperable|Metastasis
Interventions: DRUG: desatinib or sunitinib or erlotinib or everolimus or lapatinib or sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Will Hydroxychloroquine Impede or Prevent COVID-19
Status: TERMINATED
Conditions: COVID-19|Coronavirus|Coronavirus Infections|SARS-CoV 2
Interventions: DRUG: Hydroxychloroquine - Daily Dosing|DRUG: Hydroxychloroquine - Weekly Dosing|OTHER: Placebo oral tablet|DIAGNOSTIC_TEST: Monitoring Visit - Baseline|DIAGNOSTIC_TEST: Monitoring Visit - Week 4|DIAGNOSTIC_TEST: Monitoring Visit - Week 8|OTHER: Weekly Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Saturated Fat on Large Low-density Lipoprotein (LDL) and High-density Lipoprotein (HDL)
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DIETARY_SUPPLEMENT: Saturated Fat Diet|DIETARY_SUPPLEMENT: Saturated Fat Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prevention of Wound Complications After Cesarean Delivery in Obese Women Utilizing Negative Pressure Wound Therapy
Status: TERMINATED
Conditions: Surgical Wound Dehiscence|Wound Infection
Interventions: PROCEDURE: Negative pressure wound closure|PROCEDURE: Standard wound closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Safety, Tolerability, & Pharmacokinetics of K-285 Compared With Indomethacin Capsule in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: K-285|DRUG: Indomethacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Resilience to Sleep Deprivation and Changes in Sleep Architecture in Shoonya Meditators
Status: RECRUITING
Conditions: Sleep|Sleep Deprivation|Cognitive Change
Interventions: BEHAVIORAL: Nap Practitioners|BEHAVIORAL: Shoonya Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Negative Pressure Wound Therapy vs Standard Care Dressing
Status: WITHDRAWN
Conditions: Negative-Pressure Wound Therapy
Interventions: DEVICE: Negative pressure wound therapy|OTHER: standard care dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Omitting Drains After Repair of Peptic Ulcer Perforations
Status: RECRUITING
Conditions: Peptic Ulcer Perforations
Interventions: OTHER: Omitting of usage of intraabdominal drains after repair of peptic ulcer perforations|OTHER: Using intraabdominal drains
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: United for Health: Type 2 Diabetes Prevention in Latino Teens
Status: COMPLETED
Conditions: Prediabetic State|Insulin Resistance|Type2 Diabetes|Stress|Adolescent Development|Family Research
Interventions: BEHAVIORAL: CookingMatters|BEHAVIORAL: Parent Education|BEHAVIORAL: Physical Activity|BEHAVIORAL: Health Education|BEHAVIORAL: Mindfulness-based Stress Reduction|BEHAVIORAL: Brief Mindfulness Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of InFat™ Product on Stool Biochemistry and Stool Characteristics in Formula-fed Term Infants in China
Status: COMPLETED
Conditions: Health Behavior|Personal Satisfaction
Interventions: OTHER: InFat™ based infant formula|OTHER: Standard vegetable oil based infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Multimodal Analgesia on Pain With Insertion of Levonorgestrel-releasing IUD
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Diazepam|DRUG: Lidocaine|OTHER: Placebo pill|OTHER: Placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of an Online Safety Tool for Canadian Women Experiencing Intimate Partner Violence
Status: COMPLETED
Conditions: Domestic Violence
Interventions: BEHAVIORAL: Setting Priorities for Safety|BEHAVIORAL: Danger Assessment|BEHAVIORAL: Personalized Action Plan|BEHAVIORAL: General risk and safety information|BEHAVIORAL: Basic Emergency Safety Plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Multicenter, Randomized, Open, Parallel-designed Study to Evaluate the Efficacy and Safety of HRS-5635 Injection Alone or in Combination With Other Agents in Patients Treated for Chronic Hepatitis B
Status: RECRUITING
Conditions: Chronic Hepatitis B
Interventions: DRUG: HRS-5635 Injection|DRUG: HRS-5635 Injection|DRUG: HRS-5635 Injection|DRUG: HRS-5635 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Adenosine on Sinus and Atrioventricular Nodal Conduction in the Pediatric Transplanted Heart
Status: COMPLETED
Conditions: Sinus Bradycardia|Atrioventricular Block
Interventions: DRUG: Adenosine|PROCEDURE: Cardiac catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Collaborative Management in Pediatrics (CMP) Training Program Among Pediatric Resident Doctors and Their Patients With Asthma or Obesity
Status: COMPLETED
Conditions: Education|Asthma|Obesity
Interventions: BEHAVIORAL: Collaborative Management in Pediatrics (CMP) Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Functional Evaluation of a Standard and a High-flexion Knee Prosthesis Using Thigh-calf Contact Force Measurements
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee
Interventions: PROCEDURE: Total Knee Arthroplasty (TKA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Evaluation of Tolerance and Safety of Early Enteral Nutrition in Children After Percutaneous Endoscopic Gastrostomy Placement
Status: UNKNOWN
Conditions: Enteral Nutritional Support
Interventions: DIETARY_SUPPLEMENT: Resumption of feeding 3 hours after PEG placement|DIETARY_SUPPLEMENT: Resumption of feeding 8 hours after PEG placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: J-pouch Versus Side-to-end Coloanal Anastomosis After Preoperative Radiotherapy and Total Mesorectal Excision for Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: PROCEDURE: j-pouch coloanal anastomosis|PROCEDURE: side-to-end coloanal anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Post Market Clinical Follow Up Study for ReliaTack™ Articulating Reloadable Fixation Device With Deep Purchase Tacks
Status: COMPLETED
Conditions: Inguinal Hernia|Ventral Hernia
Interventions: DEVICE: ReliaTack™ Articulating Reloadable Fixation Device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Selinexor Combined With R-GDP Regimen for TP53-altered R/R DLBCL
Status: NOT_YET_RECRUITING
Conditions: Relapsed or Refractory B-cell Lymphoma
Interventions: DRUG: SR-GDP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study, Looking at How Ryzodeg® (Insulin Degludec/Insulin Aspart) Works in People With Type 2 Diabetes in Local Clinical Practice
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Degludec/Insulin Aspart
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Surgical Specification and Efficacy Evaluation of Total Laparoscopic Left Liver Resection
Status: UNKNOWN
Conditions: Laparoscopic Hepatectomy|Hepatocellular Carcinoma
Interventions: PROCEDURE: laparoscopic hepatectomy|PROCEDURE: open liver resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of the Impact of Vitamin A on Maternal Mortality
Status: COMPLETED
Conditions: Vitamin A Deficiency|Maternal Mortality|Maternal Morbidity
Interventions: DIETARY_SUPPLEMENT: Vitamin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Lemborexant on the Ability to Sleep During Daytime
Status: RECRUITING
Conditions: Shift-Work Sleep Disorder
Interventions: DRUG: Lemborexant 5 MG [Dayvigo]|OTHER: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ARRY-371797 in Patients With LMNA-Related Dilated Cardiomyopathy
Status: COMPLETED
Conditions: LMNA-Related Dilated Cardiomyopathy
Interventions: DRUG: ARRY-371797, p38 inhibitor; oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Implantable Microneuromodulator for the Treatment of Chronic Shoulder Pain in Chronic Post-Stroke Subjects
Status: COMPLETED
Conditions: Shoulder Pain Chronic
Interventions: DEVICE: Battery Powered Microneuromodulator (BBPM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility Study of Umbilical Cord Blood Cells for Infants With Hypoplastic Left Heart Syndrome
Status: TERMINATED
Conditions: Hypoplastic Left Heart Syndrome
Interventions: BIOLOGICAL: Autologous Umbilical Cord Blood|BIOLOGICAL: Autologous Umbilical Cord Blood
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Adult Participants With Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: Troriluzole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Laparoscopic-assisted Transversus Abdominus Plane (TAP) Block Compared to Ultrasound-guided TAP Block in Minimally Invasive Gynecologic Surgeries: A Prospective, Randomized Control Trial.
Status: COMPLETED
Conditions: the Efficacy of Analgesia of Laparoscopic TAP Block in Minimally Invasive Gynecology Surgeries
Interventions: DRUG: TAP block with liposomal bupivacaine and bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Intrapulmonary Percussive Ventilation (IPV) on Gastro-oesophageal Reflux (GOR).
Status: COMPLETED
Conditions: Gastro-oesophageal Reflux
Interventions: OTHER: sitting position
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib, Paclitaxel, and Carboplatin in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Ciliary Body and Choroid Melanoma, Medium/Large Size|Extraocular Extension Melanoma|Iris Melanoma|Recurrent Intraocular Melanoma|Recurrent Melanoma|Stage IV Melanoma
Interventions: DRUG: carboplatin|DRUG: paclitaxel|DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imatinib Mesylate in Treating Patients With Persistent or Recurrent Ovarian Epithelial or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Primary Peritoneal Cavity Cancer|Recurrent Ovarian Epithelial Cancer
Interventions: DRUG: imatinib mesylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Macrophages, Portal Hypertension, and Liver Function During AbbVie Treatment of Chronic Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C
Interventions: PROCEDURE: Functional Hepatic Nitrogen Clearance (FHNC)|PROCEDURE: Galactose Elimination Capacity (GEC)|PROCEDURE: Liver vein catheterization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Liver Test Study of Using JKB-122 in Hepatitis C Virus (HCV)-Positive Patients Nonresponsive to Prior Interferon Based Therapies
Status: TERMINATED
Conditions: Chronic Hepatitis C
Interventions: DRUG: JKB-122 5mg|DRUG: JKB-122 15mg|DRUG: JKB-122 35mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Use of the Usual Chemotherapy Before and After Surgery for Removable Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Adenosquamous Carcinoma|Resectable Pancreatic Adenocarcinoma|Pancreatic Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Irinotecan Hydrochloride|DRUG: Leucovorin Calcium|DRUG: Fluorouracil|PROCEDURE: Resection|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Clinical Trial Comparing Surgisis AFP to Advancement Flap for the Repair of Anal Fistulas
Status: COMPLETED
Conditions: Anal Fistula
Interventions: DEVICE: Surgisis Biodesign Anal Fistula Plug (Surgisis® AFP)|DEVICE: Flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurofeedback and Computerized Cognitive Training in Different Settings for Children and Adolescents With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Neurofeedback training|BEHAVIORAL: Computerized cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Korea Transradial Coronary Intervention Prospective Registry (KOTRI)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Transradial coronary angiography and intervention|PROCEDURE: Transfemoral coronary angiography and intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Effectiveness of Epoetin Alfa on Hemoglobin Levels and Blood Transfusions in Cancer Patients Receiving Chemotherapy
Status: COMPLETED
Conditions: Anemia|Neoplasms
Interventions: DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nitrofurantoin and Urinary Tract Infections (UTIs)
Status: TERMINATED
Conditions: Urinary Tract Infections
Interventions: DRUG: Nitrofurantoin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tandospirone Citrate in the Treatment of Patients With Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: Usual dose treatment of Tandospirone|DRUG: Comparative high dose of tandospirone treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Z Shaped and Conventional Sulcular Incisions on Healing and Interproximal Bone Loss in Implant Surgery
Status: UNKNOWN
Conditions: Bone Loss|Healing Surgical Wounds
Interventions: PROCEDURE: Z shaped incision|PROCEDURE: H shaped incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity Study of an Inactivated H5N1 Influenza Vaccine (Whole Virion, Vero Cell Derived)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Whole virion, Vero cell-derived influenza vaccine containing H5N1 HA antigen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Evaluation of Percutaneous Ommaya Capsule Injection of Autologous Bi-dimensional Specific T Cells in the Treatment of Glioma and in Combination With Pemetrexed in the Treatment of Brain/Meningeal Metastases
Status: UNKNOWN
Conditions: Glioma|Brain Metastases
Interventions: BIOLOGICAL: Autologous progenitor expansion -T|DRUG: pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of the Efficacy and Safety of Izokibep in the Treatment of Non-anterior Uveitis
Status: COMPLETED
Conditions: Uveitis
Interventions: DRUG: Izokibep|DRUG: Prednisone/Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gamma-Amino Butyric Acid (GABA)-A Alpha2/3 Study
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Merck L-830982|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Perfusion Index, T Wave Amplitude, Systolic Blood Pressure and Heart Rate
Status: UNKNOWN
Conditions: Injections, Intravenous
Interventions: DRUG: Epinephrine|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Repeated Insult Patch Test of Personal Lubricants
Status: COMPLETED
Conditions: Erythema|Edema
Interventions: DEVICE: Experimental: Novel lubricant Miami Fragrance|DEVICE: Experimental: Novel lubricant Miami no Fragrance|DEVICE: KY Liquid lubricant|DEVICE: Astroglide Gel lubricant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Prophylactic Double Thermal Ablation After Endoscopic Mucosal Resection of Large Non-Pedunculated Colorectal Polyps
Status: RECRUITING
Conditions: Colorectal Cancer|Polyp of Colon
Interventions: PROCEDURE: Hybrid Argon Plasma Coagulation (h-APC)|PROCEDURE: Snare tip soft coagulation (STSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fibrinogen Early In Severe Trauma studY Junior
Status: UNKNOWN
Conditions: Trauma|Hemorrhage|Coagulopathy|Pediatrics
Interventions: DRUG: Fibrinogen Concentrate|DRUG: Cryoprecipitate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Simvastatin and Albumin Paclitaxel in Treating ES-SCLC Patients Relapsed From 1st Chemotherapy
Status: UNKNOWN
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Albumin Paclitaxel|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Mechanism of Online Peer Companion Intervention on Children With Autism Spectrum Disorders
Status: RECRUITING
Conditions: Autism Spectrum Disorders
Interventions: BEHAVIORAL: Online Peer Companion Intervention|BEHAVIORAL: Wait-List
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regulation of Branched-chain Amino Acid Metabolism in Pre-Diabetes
Status: COMPLETED
Conditions: Branched-chain Amino Acid Metabolism|Insulin Sensitivity
Interventions: OTHER: Pre-Diabetes Group - 6-mo Aerobic and Resistance combined exercise training|OTHER: GBP Group - Non-diabetics intending to undergo Gastric Bypass surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Evaluation of the 3 Allergens: Methyldibromoglutharonitrile, Parthenolide and Goldnatriumthiosulphate
Status: COMPLETED
Conditions: Allergic Contact Dermatitis
Interventions: DRUG: Goldnatriomthiosulphate, MDBGN, parthenolide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prophylactic Urethral Stenting With Memokath After Prostate Implantation for Prostate Adenocarcinoma
Status: COMPLETED
Conditions: Prostate Cancer|Post-Brachytherapy Bladder Outlet Obstruction
Interventions: DEVICE: Memokath 028SW Urethral Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sodium Benzoate and/or N-Acetylcysteine Added to TAU in Patients With Early Schizophrenia Spectrum Disorder.
Status: COMPLETED
Conditions: Schizophrenia|Schizophreniform Disorders|Schizoaffective Disorder
Interventions: DRUG: Sodium Benzoate|DRUG: N-Acetylcysteine|DRUG: Placebo|DRUG: Sodium Benzoate Plus N-Acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Transcranial Magnetic Stimulation (TMS) for Treatment of Auditory Hallucinations
Status: COMPLETED
Conditions: Auditory Hallucinations
Interventions: DEVICE: Transcranial magnetic stimulation|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rhomboid Intercostal and Subserratus / Paravertebral Block
Status: NOT_YET_RECRUITING
Conditions: Analgesia|Thoracic|Anesthesia
Interventions: PROCEDURE: PARAVERTEBRAL BLOCK|PROCEDURE: RHOMBOID INTERCOSTAL AND SUBSERRATUS PLANE BLOCK|PROCEDURE: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Dental Biofilm Control During Orthodontic Treatment
Status: RECRUITING
Conditions: Gingivitis|Malocclusion
Interventions: DEVICE: fixed metal orthodontic appliance|DEVICE: fixed non-metal orthodontic appliance|PROCEDURE: oral hygiene|DRUG: Chlorhexidine mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The DPP-4 Inhibitor Vildagliptin as Adjunct in Major Depressive Disorder Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Vildagliptin 50 MG|DRUG: Escitalopram 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pre- and Postoperative Chemotherapy Including Bevacizumab in Potentially Curable Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Tomography (PET) Imaging Study to Evaluate Enzyme Availability in the Central Nervous System Before and After CC-97489 Administration in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: CC-97489|DRUG: [18F]T-401|DRUG: [11C]MK-3168
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Trial of Anterograde Single Balloon Versus Spirus Enteroscopy
Status: TERMINATED
Conditions: Gastrointestinal Hemorrhage|Inflammatory Bowel Disease|Gastrointestinal Neoplasms
Interventions: PROCEDURE: Single Balloon|PROCEDURE: Spirus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate Concurrent VRP-HER2 Vaccination and Pembrolizumab for Patients With Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|HER2+ Breast Cancer
Interventions: BIOLOGICAL: VRP-HER2|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT