pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients
Status: COMPLETED
Conditions: Adenomatous Polyposis Coli
Interventions: DRUG: Erlotinib|DRUG: Sulindac|DRUG: Placebo A|DRUG: Placebo B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Cardiac Safety Study of an Investigational Drug to See How if Affects the Heart in People With Parkinson's Disease Complicated by Motor Fluctuations "OFF" Episodes
Status: COMPLETED
Conditions: Parkinson's Disease|Off Episodes of Parkinson Disease
Interventions: DRUG: APL-130277|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acetaminophen and Impaired Musculoskeletal Adaptations to Exercise Training
Status: COMPLETED
Conditions: Sarcopenia|Osteoporosis|Aging
Interventions: BEHAVIORAL: Resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study Evaluating the Effects of a High Viscosity Non-starch Polysaccharide (PolyGlycopleX® - PGX®) on Glycemic Control, Cardiometabolic Risk Factors and Weight Loss in Overweight and Obese Type II Diabetics
Status: TERMINATED
Conditions: Type II Diabetes Mellitus|Obesity
Interventions: DIETARY_SUPPLEMENT: PolyGlycopleX® - PGX®|DIETARY_SUPPLEMENT: Rice Flour (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture Combined With Hydroxychloroquine
Status: COMPLETED
Conditions: Primary Sjögren's Syndrome
Interventions: OTHER: Acupuncture combined with oral hydroxychloroquine sulfate tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BOSS Study: A Study of Fuzeon Using the Needle-Free Biojector 2000 in Patients With HIV-1 Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: enfuvirtide [Fuzeon]|DRUG: enfuvirtide [Fuzeon]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess CD19-targeted Immunotherapy T Cells in Patients With Relapsed or Refractory CD19+ B Cell Leukemia
Status: UNKNOWN
Conditions: Leukemia, B-Cell
Interventions: DRUG: anti-CD19-CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exercise With Wearable Walking Assist Robot in Various Environments
Status: COMPLETED
Conditions: Aging
Interventions: OTHER: Over-ground walking without GEMS-H|DEVICE: Over-ground walking with GEMS-H with resist mode|DEVICE: Stair ascent with GEMS-H with assist mode|DEVICE: Incline walking with GEMS-H with assist mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Compare Blood Sugar Level Between Lantus in the Morning and Other Insulins in Type 1 Diabetes Adolescents
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Lantus (insulin glargine [rDNA origin] injection)|DRUG: Humulin N|DRUG: Humulin L|DRUG: Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Robot-Assisted Gait Training In Addition To Conventional Rehabilitation Provide Better Outcomes In Children With Cerebral Palsy?
Status: COMPLETED
Conditions: Cerebral Palsy|Robotics
Interventions: OTHER: conventional therapy|OTHER: RoboGait®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplementation of VigantOL® Oil Versus Placebo as Add-on in Patients With Relapsing Remitting Multiple Sclerosis Receiving Rebif® Treatment
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: VigantOL oil plus interferon beta-1a (Rebif)|DRUG: Placebo plus interferon beta-1a (Rebif)|BIOLOGICAL: Interferon beta-1a (Rebif®) alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase-I Study of a Nanoparticle-based Peptide Vaccine Against Dengue Virus
Status: COMPLETED
Conditions: Dengue
Interventions: BIOLOGICAL: LD vehicle-GNP|BIOLOGICAL: LD PepGNP-Dengue|BIOLOGICAL: HD vehicle-GNP|BIOLOGICAL: HD PepGNP-Dengue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Best Management of Muscle Relaxation- Objective Monitoring
Status: COMPLETED
Conditions: Residual Paralysis, Post Anesthesia
Interventions: COMBINATION_PRODUCT: Protocol for Management of Muscle Relaxation With Rocuronium Using Objective Monitoring and Reversal With Neostigmine or Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics and Safety Study of Omecamtiv Mecarbil in Healthy Japanese Adults
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Omecamtiv mecarbil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Glass Ionomer Sealant Versus Resin Sealant for Pits and Fissures of the First Permanent Molars
Status: NOT_YET_RECRUITING
Conditions: Pits and Fissures Sealant
Interventions: OTHER: Glass ionomer sealant|OTHER: Resin based sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Endoplasmic Reticulum Stress on Metabolic Function
Status: COMPLETED
Conditions: Insulin Resistance|Diabetes|Obesity
Interventions: DRUG: tauroursodeoxycholic acid|OTHER: placebo|DRUG: sodium phenylbutyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intravenous (IV) Iron Preparation (VIT-45) in the Treatment of Restless Legs Syndrome (RLS)
Status: COMPLETED
Conditions: Restless Legs Syndrome (RLS)
Interventions: DRUG: Ferric Carboxymaltose (FCM)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain Control in Children Undergoing Laparoscopic Appendectomy: Peripheral Nerve Block Versus Local Anesthetic
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Bupivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Balloon-Expandable Edwards Valve and Self-Expandable CoreValve Evolut R or Evolut PRO System for the Treatment of Small, Severely Dysfunctional Surgical Aortic Bioprotheses. The 'LYTEN' Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Valve Stenosis|Regurgitation, Aortic|Prosthesis Failure
Interventions: PROCEDURE: TAVI_ViV procedure with Edwards valve|PROCEDURE: TAVI_ViV procedure with CoreValve system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Predict Weight Loss Response to Liraglutide (Saxenda®), From fMRI-based Determination of Food Cue Reactivity
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Saxenda®|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Exercise Counseling to Promote Workability
Status: UNKNOWN
Conditions: Physical Functioning|Musculoskeletal Pain|Quality of Life|Physical Activity
Interventions: BEHAVIORAL: Personalized Exercise Counseling (PEC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antiresorptive Drug Continuation Compared With Drug Holiday in Cancer Patients Needing Tooth Extraction
Status: COMPLETED
Conditions: Osteonecrosis Due to Drugs, Jaw
Interventions: OTHER: Continuation of antiresorptives in relation to tooth extraction (surgical tooth removal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study Evaluating the Role of Ultra-sound Guidance When Drawing Radial Arterial Blood Samples
Status: COMPLETED
Conditions: Radial Artery|Ultrasonography
Interventions: PROCEDURE: RAP palpation only|PROCEDURE: RAP with ultrasound guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Sabatolimab and Magrolimab-based Treatment in AML or Higher Risk MDS Participants
Status: WITHDRAWN
Conditions: Myelodysplastic Syndromes|Acute Myeloid Leukemia
Interventions: DRUG: Sabatolimab|DRUG: Magrolimab|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrapulmonary Pharmacokinetics of Antibiotics
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Telithromycin|DRUG: azithromycin|PROCEDURE: bronchoalveolar lavage|DRUG: Telithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Milk Plus Exercise: A Novel Strategy to Treat Diabetes.
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Skim Milk|BEHAVIORAL: High intensity interval training|OTHER: Placebo|DIETARY_SUPPLEMENT: Macronutrient isoenergetic control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Checkpoint Inhibitor Combinations Therapy as First Line for HCC Via IT
Status: RECRUITING
Conditions: Liver Cancer|Antibody
Interventions: DRUG: ipilimumab+pembrolizumab or ipilimumab+durvalumab, idarubicin, bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Flow Restriction Training in Patients With Weight Bearing Restrictions After Knee Surgery
Status: COMPLETED
Conditions: Cartilage, Articular|Tibial Meniscus Injuries
Interventions: OTHER: Physical therapy with BFR-LLST
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Melatonin and Diazepam for Prevention of Recurrent Simple Febrile Seizures
Status: COMPLETED
Conditions: Febrile Seizures
Interventions: DRUG: oral melatonin|DRUG: oral diazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Astaxanthin in Moderate to Severe Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Astaxanthin Oral Capsule|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of Remsima® in the Treatment of Inflammatory Bowel Diseases Among Saudi Arabia Patients
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Crohn Disease|Fistulizing Crohn's Disease|Ulcerative Colitis
Interventions: DRUG: Infliximab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acalabrutinib for GVHD Prophylaxis in Allogeneic Hematopoietic Stem Cell Transplantation in Lymphomas and Leukemia
Status: WITHDRAWN
Conditions: Lymphoma|Leukemia
Interventions: DRUG: Acalabrutinib, tacrolimus, methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells
Status: RECRUITING
Conditions: EGFR Gene Mutation|Glioblastoma|MGMT-Unmethylated Glioblastoma|Recurrent Glioblastoma
Interventions: BIOLOGICAL: E-SYNC T Cells|DRUG: Cyclophosphamide (non-investigational)|DRUG: Fludarabine (non-investigational)|PROCEDURE: Leukapheresis|PROCEDURE: Surgical resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulating Effects of Oil Palm Phenolics in Uncontrolled Insulin-treated Type 2 Diabetes Mellitus
Status: TERMINATED
Conditions: Uncontrolled Insulin-treated Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Oil Palm Phenolics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Relationships of Resistance Exercise, Walking, Myokine Secretion, Sarcopenia, Muscle Loss, Quality of Life, and Predictors in Cancer Patients Receiving Chemoradiotheray
Status: RECRUITING
Conditions: Cancer
Interventions: BEHAVIORAL: resistance exercise and walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Safety and Efficacy of HAIC+Tislelizumab+Regorafenib in Patients With Colorectal Liver Metastases
Status: RECRUITING
Conditions: Colorectal Liver Metastases
Interventions: DRUG: Tislelizumab|DRUG: Regorafenib|OTHER: HAIC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: [18F]FTC-146 PET/MRI in Healthy Volunteers and in CRPS and Sciatica
Status: COMPLETED
Conditions: Complex Regional Pain Syndrome|Sciatica
Interventions: DRUG: [18F]-FTC-146
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Acute Leg Cycling at Various Intensities on RLS Severity in Persons With MS
Status: WITHDRAWN
Conditions: Multiple Sclerosis|Restless Legs Syndrome
Interventions: BEHAVIORAL: Exercise Conditions|BEHAVIORAL: Exercise Conditions|BEHAVIORAL: Exercise Conditions|BEHAVIORAL: Exercise Conditions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CX-DZ-Ⅱ Intelligent Electroacupuncture Instrument for Neck Pain
Status: COMPLETED
Conditions: Acupuncture|Neck Pain
Interventions: DEVICE: intelligent electroacupuncture instrument|DEVICE: Hwato electroacupuncture instrument
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effectiveness of Sambiloto Herbs (Andrographis Paniculata) and Brisk Walking Exercise on Blood Glucose of Obese Patients
Status: NOT_YET_RECRUITING
Conditions: MeSH
Interventions: DIETARY_SUPPLEMENT: Herbal Medicine Sambiloto|BEHAVIORAL: Brisk Walking|COMBINATION_PRODUCT: Brisk Walking and Herbal Medicine Sambiloto
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing an Integrative, Recovery-Based, Post-Acute COVID-19 Syndrome (PACS) Psychotherapeutic Intervention
Status: ACTIVE_NOT_RECRUITING
Conditions: Long COVID
Interventions: BEHAVIORAL: Long COVID Coping and Recovery (LCCR) Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tacrolimus/Methotrexate Versus Cyclosporine/Methotrexate for Prophylaxis of Graft Versus Host Disease
Status: COMPLETED
Conditions: Graft vs Host Disease
Interventions: DRUG: Tacrolimus|DRUG: Cyclosporine|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combined Human Milk Oligosaccharides (HMOs) and Probiotics Intervention for Children With Autism
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder|Neurodevelopmental Disorders|Anxiety
Interventions: DIETARY_SUPPLEMENT: Experimental|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liberal Versus Restrictive Use of Dobutamine in Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Output, Low|Coronary Disease
Interventions: DRUG: Liberal dobutamine protocol|DRUG: Restrictive dobutamine protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuroathletic Training in Stroke Rehabilitation? A Single-blind Randomized Controlled Pilot Study on the Potentials of Neuroathletic Training on Balance Ability in Stroke Outpatient Rehabilitation
Status: COMPLETED
Conditions: Stroke|Balance Postural
Interventions: BEHAVIORAL: Neuroathletic training|BEHAVIORAL: Traditional movement therapy in outpatient rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: tDCS Applied to the OFC: Effects on Decision-Making and Impulse Control
Status: COMPLETED
Conditions: Impulsive Behavior|Suicidal Impulses
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Synaptic Imaging and Network Activity in Treatment Resistant Depression
Status: RECRUITING
Conditions: Depressive Disorder|Depressive Disorder, Major|Depressive Disorder, Treatment-Resistant|Bipolar Disorder|Bipolar Disorder I|Bipolar Disorder II|Mood Disorders|Anhedonia
Interventions: DRUG: Ketamine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Immunogenicity of MVC-COV1901 or MVC-COV1901(Beta) Against COVID-19
Status: COMPLETED
Conditions: COVID-19 Vaccine
Interventions: BIOLOGICAL: MVC-COV1901|BIOLOGICAL: MVC-COV1901(Beta)-15|BIOLOGICAL: MVC-COV1901(Beta)-25
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Estrogen and Hot Flashes on Mood in Postmenopausal Women
Status: TERMINATED
Conditions: Menopausal Depression
Interventions: DRUG: Estradiol|OTHER: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Knowledge About Fever After Consultation in the Pediatric Emergency Department
Status: COMPLETED
Conditions: Febrile Illness|Fever|Stress
Interventions: BEHAVIORAL: The Information brochure will be created on the basis of information given by the French pediatric network Courlygone and the French National Authority for Health.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Research Study of Bone Marrow Transplantation From Unrelated or Partially Matched Related Donors
Status: COMPLETED
Conditions: Hematological Malignancies
Interventions: RADIATION: Total Body Irradiation|DRUG: Cyclophosphamide|DRUG: Tacrolimus|DRUG: Mycophenolate mofetil|DRUG: Fludarabine|DRUG: Busulfan|GENETIC: Hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating 18F-FDG PET/CT With Liver SUVmax-based Criteria for Prognosis of Patients With Diffuse Large B-cell Lymphoma
Status: UNKNOWN
Conditions: Lymphoma, Large B-Cell, Diffuse
Interventions: DEVICE: 18F-FDG PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Preclinical Evaluation of Multimodal Therapeutic Strategies in Intestinal Irradiation and Inflammatory Bowel Disease From Organoids
Status: RECRUITING
Conditions: Radiation Enteritis|Inflammatory Bowel Diseases
Interventions: OTHER: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomised Trial Comparing Thermal Ablation With Adrenalectomy in the Treatment of Unilateral Asymmetric PA
Status: RECRUITING
Conditions: Primary Aldosteronism
Interventions: PROCEDURE: Thermal ablation of aldosterone producing adenoma.|PROCEDURE: Unilateral adrenalectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phenotypic Spectrum of CTCs in Tumors of the Female Reproductive System
Status: COMPLETED
Conditions: Breast Cancer|Ovarian Cancer|Endometrial Cancer
Interventions: OTHER: Taking 5 ml of venous blood at different time intervals|OTHER: Taking 5 ml EDTA-stabilized ascitic fluid sampled during laparoscopy if any
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Probiotics on Metabolic Syndrome ,Intestinal Microflora and SCFA.
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Probiotics 1|DIETARY_SUPPLEMENT: Probiotics 2|DIETARY_SUPPLEMENT: Probiotics 3|DIETARY_SUPPLEMENT: Probiotics 4|DIETARY_SUPPLEMENT: Probiotics 5|DIETARY_SUPPLEMENT: Placebo 1|DIETARY_SUPPLEMENT: Probiotics 6|DIETARY_SUPPLEMENT: Probiotics 7|DIETARY_SUPPLEMENT: Placebo 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Sodium Chloride or Its Substitute Salt Potassium Chloride on Vascular Function
Status: NOT_YET_RECRUITING
Conditions: Vascular Function|Healthy|Diabetes
Interventions: DIETARY_SUPPLEMENT: Soup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pre-Operative Window of Adjuvant Endocrine Therapy to Inform RT Decisions in Older Women With Early-Stage Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer Female
Interventions: DRUG: tamoxifen, letrozole, anastrozole, or exemestane|BEHAVIORAL: Patient reported outcomes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Photodynamic Therapy in Treatment of Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DEVICE: sham procedure|DEVICE: photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Incentive Designs to Increase Physical Activity Goal Adherence in a Wellness Program
Status: WITHDRAWN
Conditions: Physical Activity
Interventions: BEHAVIORAL: Active Rewards|BEHAVIORAL: Lottery 1|BEHAVIORAL: Lottery 2|BEHAVIORAL: Broadcasting winners|BEHAVIORAL: Active Rewards Doubled
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Open Label Randomized Study to Compare the Efficacy and Safety of Rituximab Plus Lenalidomide (CC-5013) Versus Rituximab Plus Chemotherapy Followed by Rituximab in Subjects With Previously Untreated Follicular Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Follicular Lymphoma
Interventions: DRUG: Rituximab|DRUG: Lenalidomide|DRUG: Rituximab - CHOP|DRUG: Rituximab - CVP|DRUG: Rituximab - Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Auricular Acupressure as an Adjunct Treatment for Neonatal Abstinence Syndrome (NAS)
Status: COMPLETED
Conditions: Neonatal Abstinence Syndrome|Withdrawal
Interventions: OTHER: Auricular acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leveraging Technological Advancements to Improve the Treatment of Trichotillomania
Status: RECRUITING
Conditions: Trichotillomania (Hair-Pulling Disorder)|Trichotillomania|Hair Pulling
Interventions: DEVICE: HabitAware Keen2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tissue Engineered Nasal Cartilage for Regeneration of Articular Cartilage
Status: COMPLETED
Conditions: Cartilage Lesion|Degenerative Lesion of Articular Cartilage of Knee
Interventions: BIOLOGICAL: Tissue engineered cartilage graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Interrogation of the Cardiomyopathy of Chronic Kidney Disease With advancEd caRdiac Imaging
Status: TERMINATED
Conditions: Chronic Kidney Diseases|Cardiomyopathies|Cardiovascular Diseases|Cardiac Disease
Interventions: DIAGNOSTIC_TEST: Cardiac MRI and contrast-enhanced cardiac CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Pilates Exercises on Patients With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: ( Traditional dietary advice )|OTHER: (Pilates exercises)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children From 6 Years to < 18 Years of Age With AAV.
Status: NOT_YET_RECRUITING
Conditions: Vasculitis
Interventions: DRUG: Avacopan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ED90 Determination of Carbetocin for the Prevention of Uterine Atony in Women Undergoing an Elective Cesarean Delivery
Status: UNKNOWN
Conditions: Postpartum Hemorrhage|Uterine Atony
Interventions: DRUG: Carbetocin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow Autograft in Limb Ischemia
Status: COMPLETED
Conditions: Peripheral Vascular Diseases
Interventions: PROCEDURE: Bone marrow harvest|PROCEDURE: Bone marrow harvest
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 24 Months Follow-up, Two Arm Study to Compare the Cardiovascular Profile in a Regimen With Everolimus + Mycophenolic Acid (MPA) Versus (vs.) a Regimen of CNI+MPA in Maintenance Renal Transplant Recipients
Status: COMPLETED
Conditions: Renal Transplant
Interventions: DRUG: Everolimus|DRUG: Tacrolimus|DRUG: Mycophenolic acid (MPA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Atorvastatin on the Nitrogen Oxide-system in Patients With Type 2 Diabetes and Nephropathy
Status: COMPLETED
Conditions: Nephropathy|Cardiovascular Diseases|Diabetes Mellitus
Interventions: DRUG: Atorvastatin|DRUG: Unikalk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AFAMOSI: Efficacy and Safety of Afatinib Followed by Osimertinib Compared to Osimertinib in Patients With EGFRmutated/T790M Mutation Negative Nonsquamous NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-squamous NSCLC
Interventions: DRUG: Afatinib|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Levobupivacaine and Ropivacaine in the Hip Fractures of the Elderly
Status: COMPLETED
Conditions: Hip Fractures
Interventions: DRUG: Levobupivacaine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual-light Antibacterial Photodynamic Therapy as an Adjunctive Treatment to Corticosteroid Treatment in OLP
Status: RECRUITING
Conditions: Oral Lichen Planus|Dental Plaque|Oral Bacterial Infection
Interventions: DEVICE: Lumoral treatment|OTHER: Standard oral hygiene self care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prebiotics and Stress Reduction in Women
Status: COMPLETED
Conditions: Stress, Psychological
Interventions: DIETARY_SUPPLEMENT: Relax+|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tumor Nutritional Therapy in the First-line Treatment of Stage IV NSCLC
Status: RECRUITING
Conditions: Long-Term Effects Secondary to Cancer Therapy
Interventions: DIETARY_SUPPLEMENT: Cancer nutritional treatment regimen (Spirulina Bifidobacterium Capsules, Fish Oil Grape Seed Blueberry Soft Capsules, Ganoderma Spore Oil Soft Capsules)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Ectoin Allergy Nasal Spray and Ectoin Allergy Eye Drops in the Treatment of Seasonal Allergic Rhinitis (SAR) in Children and Adolescents
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis|Seasonal Allergic Conjunctivitis
Interventions: DEVICE: ect4allergy Nasal Spray (ANS01) and Eye Drops (AAT01)|DEVICE: Placebo products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Standing in Minors Operated on for Idiopathic Scoliosis
Status: RECRUITING
Conditions: Idiopathic Scoliosis|ERAS
Interventions: PROCEDURE: anticipated bipedal standing position in the immediate post-operative phase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Clinical Trial to Evaluate the Safety and Efficacy of Retreatment With Intra-articular LBSA0103 Injections in the Patients With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of Knee
Interventions: DRUG: LBSA0103 (BDDE cross-linked sodium hyaluronate gel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib and Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: erlotinib hydrochloride|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gonadotropin-releasing Hormone (GnRH) Downregulation Versus Oral Anticonception Prior to ART in Postoperative Endometriosis Patients
Status: COMPLETED
Conditions: Endometriosis|Infertility
Interventions: DRUG: triptorelin|DRUG: ethinylestradiol + dienogest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Bedaquiline, Delamanid, Levofloxacin, Linezolid, and Clofazimine to Treat MDR-TB
Status: RECRUITING
Conditions: Tuberculosis, Multidrug-Resistant
Interventions: DRUG: Delamanid|DRUG: Levofloxacin|DRUG: Bedaquiline|DRUG: Clofazimine|DRUG: Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of Balloon Catheter Combined With Oxytocin Induction in Nulliparous Women With Estimated Fetal Weight ≥3500g at 39-40 Weeks of Gestation
Status: UNKNOWN
Conditions: Macrosomia, Fetal
Interventions: PROCEDURE: balloon catheter combined with oxytocin induction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Postoperative Pain After Using 3MIX-TATIN Versus Calcium Hydroxide Iodoform Paste In Necrotic Primary Molars Treated by Lesion Sterilization and Tissue Repair Therapy
Status: COMPLETED
Conditions: Necrotic Pulp|Postoperative Pain
Interventions: DRUG: Calcium Hydroxide, Iodoform, paste|DRUG: 3-mixtatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Cranberry Ingestion and Cycling Related Immunity and Inflammation
Status: COMPLETED
Conditions: Inflammatory Response|Metabolic Disturbance|Immune Suppression
Interventions: DIETARY_SUPPLEMENT: Cranberry Juice|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of GABAB Agonist on Visceral Hyperalgesia in NCCP patientsChinese?
Status: TERMINATED
Conditions: Non-Cardiac Chest Pain
Interventions: DRUG: Baclofen, Diltiazem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pregabalin and Analgesia After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Pain Postoperative
Interventions: DRUG: Pregabalin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Metabolic Responses of Dapagliflozin vs Sitagliptin in T2DM Patients Inadequately Controlled With Insulin Therapy
Status: COMPLETED
Conditions: Type 2 Diabetes|Ketonemia
Interventions: DRUG: Dapagliflozin 10 mg|DRUG: Sitagliptin 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Qingkailing Injection Versus Puerarin Injection on Withdrawal Rate of Corticosteroids in Patients With Active Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Puerarin injection 400 mg|DRUG: Qingkailing injection 40 ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Acute Promyelocytic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: arsenic trioxide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: tretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Omega Study: Evaluation of the Safety and Efficacy of the Omega System for the Treatment of BPH
Status: RECRUITING
Conditions: Benign Prostatic Hyperplasia|Lower Urinary Tract Symptoms
Interventions: DEVICE: Omega
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Valsartan 80 Mg-Referenced, Therapeutic Exploratory Clinical Study to Evaluate the Antihypertensive Efficacy of Fimasartan 30 mg During 24 Hours in Patients With Mild to Moderate Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Fimasartan|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Intake of Salmon and Bone Health
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DIETARY_SUPPLEMENT: Tailor-made salmon with high levels of vitamin D3 and K1|DIETARY_SUPPLEMENT: Tailor-made salmon with low levels of vitamin D3 and high K1|DIETARY_SUPPLEMENT: Tailor-made salmon with high levels of vitamin D3 and low K1|DIETARY_SUPPLEMENT: Supplement with vitamin D and Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of 'Samalochana' Program on Women Who Have Experienced Intimate Partner Violence (IPV)
Status: COMPLETED
Conditions: Domestic Violence|Intimate Partner Violence
Interventions: OTHER: Samalochana Counselling|OTHER: Wait list control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trivalent Salmonella Conjugate Vaccine (TSCV)
Status: RECRUITING
Conditions: Trivalent Salmonella Conjugate Vaccine (TSCV)
Interventions: DRUG: TSCV (Full-strength)|DRUG: TSCV (Half-strength)|DRUG: Typbar-TCV|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: 12 Weeks of Resistance Band Exercise Impacts on Adiposity, Hormones, and Blood Pressure in Postmenopausal Women
Status: COMPLETED
Conditions: Hypertension|Hormone Disturbance|Adiposity
Interventions: OTHER: Resistance band exercise intervention|OTHER: No exercise intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of the Early Activity of Ixekizumab (LY2439821) in Moderate-to-Severe Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Ixekizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reflexology on Seizure Frequency, Fatigue, Stress and Sleep Quality in Epilepsy Patients
Status: RECRUITING
Conditions: Reflexology|Epilepsy|Fatigue|Stress
Interventions: BEHAVIORAL: Reflexology Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PK and Safety of HCP1303 and Co-administration of HGP1201, HIP1402 Under Fed Condition in Healthy Male Volunteers
Status: COMPLETED
Conditions: Erectile Dysfunction|Prostatic Hyperplasia
Interventions: DRUG: HCP1303|DRUG: HGP1201|DRUG: HIP1402
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACOART RF CLOSURE:Radiofrequency for Varicose Veins of Lower Extremity in China
Status: COMPLETED
Conditions: Varicose Veins of Lower Limb
Interventions: DEVICE: ERA-C70,ERA-C30 and ERA-G5|DEVICE: ClosureFast™ and ClosureRFG™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Sulfasalazine and Oral Lichen Planus
Status: ACTIVE_NOT_RECRUITING
Conditions: Oral Lichen Planus|Topical Sulfasalazine|Corticosteroids
Interventions: DRUG: sulfasalazine 500 MG|DRUG: corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Rotator Cuff Function Restoration Balloon in Irreparable Rotator Cuff Tear
Status: UNKNOWN
Conditions: Rotator Cuff Tears
Interventions: DEVICE: Balloon implantation|PROCEDURE: Rotator cuff repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dental Pulp Regeneration by Autologous Tissue Transplantation
Status: UNKNOWN
Conditions: Dental Pulp Regeneration
Interventions: PROCEDURE: Autologous tissue transplantation|PROCEDURE: Root canal revascularization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intrapulmonary Percussive Ventilation for Children With Bronchiolitis on Non-Invasive Ventilation Support
Status: UNKNOWN
Conditions: Bronchiolitis
Interventions: DEVICE: Intrapulmonary Percussive Ventilation (Percussionaire Corp, Sandpoint, Idaho)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intracoronary Transplantation of Bone Marrow Derived Mononuclear Cells in Pediatric Cardiomyopathy
Status: COMPLETED
Conditions: Cardiomyopathy
Interventions: BIOLOGICAL: Mono Nuclear Cell (MNC) transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Effect of Adding Chronic Oral Azithromycin to Inhaled Tobramycin in People With Cystic Fibrosis (CF)
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: azithromycin|DRUG: placebo (for azithromycin)|DRUG: inhaled tobramycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contrast-enhanced Ultrasound Evaluation of Chemoembolization
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Chemoembolization, Therapeutic
Interventions: DRUG: Ultrasound contrast agent (Contrast-enhanced ultrasound)|DEVICE: Logiq E9 Scanner (Contrast-enhanced ultrasound)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dose Escalation/Dose Expansion Study of YBL-006 in Patients With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: YBL-006|DRUG: YBL-006|DRUG: YBL-006|DRUG: YBL-006|DRUG: YBL-006|DRUG: YBL-006|DRUG: YBL-006|DRUG: YBL-006
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Epothilone Plus Capecitabine Versus Capecitabine Alone in Patients With Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Metastases
Interventions: DRUG: Ixabepilone + Capecitabine|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Angiotensin (1-7) for the Treatment of COVID-19 in Hospitalized Patients
Status: WITHDRAWN
Conditions: Covid19
Interventions: DRUG: Angiotensin-(1-7)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of the Pregnane X Receptor (PXR) in Indole Signaling and Intestinal Permeability in Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases
Interventions: DIAGNOSTIC_TEST: Stool collection|DIAGNOSTIC_TEST: Biopsy collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: H1N1sw Vaccine in Adult Transplant Recipients
Status: TERMINATED
Conditions: Immunocompromised
Interventions: BIOLOGICAL: Focetria (2x H1N1 vaccine with MF59 adjuvants)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Drainage Fluid Biomarkers and Postoperative Gastrointestinal Dysfunction in Laparoscopic Colorectal Surgery
Status: RECRUITING
Conditions: Postoperative Gastrointestinal Dysfunction (POGD)
Interventions: OTHER: Biochemical testing of abdominal drainage fluid|OTHER: Cytological examination of abdominal drainage fluid|OTHER: Peripheral blood cytology tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Value of Early Post Operative Amino Acids in Critically Ill Obstetrics on Recovery Enhancement
Status: RECRUITING
Conditions: Malnutrition in Pregnancy|Malnutrition; Protein|Postpartum Disorder|Patient Satisfaction|Critical Illness
Interventions: DIETARY_SUPPLEMENT: Elemental amino-acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation and Treatment of Oral Soft Tissue Diseases
Status: COMPLETED
Conditions: Aphthous Stomatitis|Burning Mouth Syndrome|Lichen Planus|Mouth Disease|Temporomandibular Joint Disorder
Interventions: PROCEDURE: Electrocardiogram|PROCEDURE: Biopsies|PROCEDURE: Diagnostic imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Characterizing Stray Energy Injuries During Robotic Surgery
Status: COMPLETED
Conditions: Port-site Injury Caused by Stray Energy Transfer
Interventions: PROCEDURE: Laparoscopic robotic DaVinci assisted inguinal hernia repair|PROCEDURE: Standard laparoscopic inguinal hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Chemoradiotherapy With Sequential Ipilimumab and Nivolumab in Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: RADIATION: Chemoradiotherapy|DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT