pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pain, Discomfort, and Acceptance During Using Electrical Stimulation to Accelerate Orthodontic Teeth Movement
Status: COMPLETED
Conditions: Class II Malocclusion, Division 1
Interventions: DEVICE: Electrical stimulation|PROCEDURE: Traditional retraction of the front upper teeth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Tolerability of Duloxetine in Depressed Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Major Depressive Disorder|Idiopathic Parkinson Disease
Interventions: DRUG: Duloxetine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Antithrombotic Treatment for Prevention of Recurrent Ischemic Stroke in Intracranial Atherosclerotic Disease
Status: COMPLETED
Conditions: Ischemic Stroke|Intracranial Atherosclerotic Disease
Interventions: DRUG: Rivaroxaban 2.5 Mg Oral Tablet bid|DRUG: Acetylsalicyclic acid 81 mg tablet qd
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy With E6 T Cell Receptor (TCR) T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions
Status: TERMINATED
Conditions: Human Papillomavirus|HPV-16|High Grade Squamous Intraepithelial Lesion
Interventions: DRUG: Aldesleukin|BIOLOGICAL: E6 T Cell Receptor (TCR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative, Single-Center, Pediatric Taste Test Study of Omnicef Versus Amoxicillin Antibiotic Suspension Medications
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: cefdinir (Omnicef)|DRUG: amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Efficacy and Safety of Perioperative Chemotherapy Plus PD-1 Antibody in Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Camrelizumab|DRUG: Oxaliplatin|DRUG: S1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Soy Supplementation in Prostate Cancer Development
Status: COMPLETED
Conditions: Prostate Neoplasm
Interventions: DRUG: Soy Supplement|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Effects of Aerobic Exercise and Connective Tissue Massage in Postpartum Women
Status: NOT_YET_RECRUITING
Conditions: Postpartum Women
Interventions: OTHER: Aerobic exercise|OTHER: Connective tissue massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tobacco Cessation Interventions With Ohio Appalachian Smokers
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: BEHAVIORAL: Lay-led tobacco abstinence|BEHAVIORAL: Lay-led promotion of Ohio Quit Line
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Staged Consent Before Prostate Biopsy
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Meditation|PROCEDURE: Prostate Biopsy|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of Direct Peritoneal Resuscitation in High-risk Liver Transplant Recipients
Status: ACTIVE_NOT_RECRUITING
Conditions: End Stage Liver DIsease|Obesity|Acute Kidney Injury
Interventions: PROCEDURE: Direct Peritoneal Resuscitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Pemetrexed in Mesothelioma and Lung Cancer Patients With Fluid Around the Lungs or Abdomen
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Mesothelioma|Lung Neoplasms
Interventions: DRUG: pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of IL-11 (Neumega) in Von Willebrand Disease
Status: COMPLETED
Conditions: Von Willebrand Disease
Interventions: DRUG: recombinant interleukin-11|DRUG: recombinant interleukin-11|DRUG: recombinant interleukin-11
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Chimeric Antigen Receptor Modified T-cells Targeting NKG2D-Ligands
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome|Multiple Myeloma
Interventions: BIOLOGICAL: CM-CS1 T-cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Dental Occlusion on the Performance of High Level Rowers (IODPR)
Status: TERMINATED
Conditions: Dental Occlusion, Traumatic
Interventions: DEVICE: with artificial occlusal disturbance|DEVICE: without artificial occlusal disturbance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized Comparison of Transobturator Tape With the Plication of Urethral Ligaments in the Treatment of Stress Urinary Incontinence
Status: RECRUITING
Conditions: Stress Incontinence, Female
Interventions: PROCEDURE: transobturator tape operation (TOT)|PROCEDURE: urethral ligament plication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Addition of SNS-301 to Checkpoint Inhibitor Treatment in Metastatic/Recurrent SCCHN
Status: TERMINATED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: SNS-301|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Glucose Monitoring System (CGMS) in Type 2 Diabetic Patients Inadequately Controlled by Metformine Monotherapy; Analyze of Glycemic Profile Before and After Association of Glimepiride
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: GLIMEPIRIDE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial on 3D Printed Assistive Device for Continuous Ambulatory Peritoneal Dialysis
Status: UNKNOWN
Conditions: Renal Failure Chronic
Interventions: DEVICE: "Helping Hands" for CAPD bag exchange procedures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laser Acupuncture for Pain Prevention in Neonates
Status: COMPLETED
Conditions: Pain
Interventions: PROCEDURE: active laser acupuncture|PROCEDURE: placebo laser acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Virexxa (Sodium Cridanimod) w/Progestin Therapy in Pts w/Progesterone Receptor Neg Recurrent/Persistent Endometrial CA
Status: UNKNOWN
Conditions: Recurrent or Persistent Endometrial Carcinoma
Interventions: DRUG: Sodium cridanimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy in High-risk Ductal Carcinoma in Situ (DCIS)
Status: RECRUITING
Conditions: Carcinoma, Intraductal, Noninfiltrating
Interventions: DRUG: Pembrolizumab|BIOLOGICAL: Intralesional mRNA 2752
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Substrate Ablation and Remodelling in Non-paroxysmal Atrial Fibrillation (AF)
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Pulmonary vein isolation (PVI)|PROCEDURE: Pulmonary vein isolation + linear lesions|DRUG: Pharmacological Substrate modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of IVF Counseling on Psychosocial Well-Being
Status: COMPLETED
Conditions: Infertility|Psychological Distress|Infertility, Female|Depression, Anxiety|Nurse's Role
Interventions: BEHAVIORAL: Psychosocial Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ultrasound-guided Biofeedback for Transversus Abdominus Re-education in Non-specific Low Back Pain Patients
Status: COMPLETED
Conditions: Non-specific Low Back Pain (NSLBP)
Interventions: DEVICE: Real-time rehabilitative ultrasound imaging (RUSI)|OTHER: Tactile feedback (control intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Painless Local Anaesthesia With Bicarbonate Admixture
Status: COMPLETED
Conditions: Local Infiltration|Anesthesia
Interventions: DRUG: Lidocaine and sodium bicarbonate|DRUG: Lidocaine and sodium bicarbonate|DRUG: Lidocaine|DRUG: Sodium cloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reciprocating Medical Devices - a Study of a New Safety Device
Status: COMPLETED
Conditions: Osteoarthritis|Rheumatoid Arthritis|Trauma|Thyroid Nodule|Cancer
Interventions: DEVICE: Reciprocating Procedure Device (RPD) - AVANCA Re No. 1091001|DEVICE: conventional syringe - BD Ref 309604
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serplulimab Combined With FOLFIRI and Bevacizumab in the Treatment of Colon Cancer Peritoneal Metastases
Status: RECRUITING
Conditions: Unresectable Colon Cancer Peritoneal Metastases|PMMR/Ras/BRAF Wild-type
Interventions: DRUG: Serplulimab Combined With FOLFIRI and Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Fentanyl on Emergence Delirium (ED) on Children Undergoing Adeno-tonsilectomy at Kenyatta National Hospital (KNH)
Status: COMPLETED
Conditions: Emergence Delirium
Interventions: DRUG: Fentanyl|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 2 Dose-finding Study to Evaluate the Effects of BA058 in the Treatment of Postmenopausal Women With Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: teriparatide|DRUG: Placebo|DRUG: BA058 20 µg|DRUG: BA058 40 µg|DRUG: BA058 80 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Transfusion Triggers in Vascular Surgery Trial
Status: COMPLETED
Conditions: Atherosclerosis|Anemia|Aortic Aneurysm, Abdominal|Arterial Occlusive Diseases
Interventions: BIOLOGICAL: red blood cell transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Postural Changes on Plantar Pressure in Patients With Ankylosing Spondylitis
Status: UNKNOWN
Conditions: Ankylosing Spondylitis
Interventions: DIAGNOSTIC_TEST: Plantar pressure and gait
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Assess the Safety and Immunogenicity of M-001 Influenza Vaccine as a Primer to TIV in Elderly Volunteers
Status: COMPLETED
Conditions: Influenza|Healthy
Interventions: BIOLOGICAL: Two Multimeric-001 administrations followed by TIV|BIOLOGICAL: One administration of Multimeric-001 followed by TIV|BIOLOGICAL: One administration of adjuvanted M-001 followed by TIV|BIOLOGICAL: One administration of placebo followed by TIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of HIPEC Plus Apatinib and S-1 Conversion Therapy for Gastric Cancer With Positive Exfoliative Cancer Cells
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: paclitaxel apatinib S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immedaite vs Early Implant Placement in Aesthetic Area
Status: ACTIVE_NOT_RECRUITING
Conditions: Single Implant; Immediate Implant Treatment; Early Implant Treatment
Interventions: DEVICE: Implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Horticultural Therapy on Loneliness and Life Satisfaction in Elderly Adults Living in Nursing Home
Status: NOT_YET_RECRUITING
Conditions: Horticultural Therapy|Loneliness|Satisfaction, Personal|Aging
Interventions: OTHER: Horticultural Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Covid-19 Virtual Recovery Study
Status: COMPLETED
Conditions: Covid19
Interventions: BEHAVIORAL: Strength RMT|BEHAVIORAL: Strength RMT and nasal breathing|BEHAVIORAL: Endurance RMT|BEHAVIORAL: Endurance RMT and nasal breathing|BEHAVIORAL: Low dose RMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Niclosamide in Patients With COVID-19 With Gastrointestinal Infection
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: Niclosamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability and Pharmacokinetics of Guselkumab Following a Single Intravenous Administration in Healthy Japanese Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Guselkumab Dose 1|DRUG: Guselkumab Dose 2|DRUG: Guselkumab Dose 3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Pilot Study of Emapalumab for the Treatment of CAR T-Cell Therapy-Associated Prolonged Cytopenia
Status: NOT_YET_RECRUITING
Conditions: Cytopenia
Interventions: DRUG: Emapalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Explore Effectiveness of Sublingual Fentanyl Spray in Emergency Department Patients With Acute Pain
Status: WITHDRAWN
Conditions: Acute Pain
Interventions: DRUG: Morphine 6 mg|DRUG: Fentanyl 100 µg|DRUG: Fentanyl 200 µg|DRUG: Fentanyl 400 µg|DRUG: Placebo Sublingual Spray|DRUG: Intravenous Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the ViSiGiTM Calibration System
Status: UNKNOWN
Conditions: Enhance Delineation of the Stomach Anatomy and the Surgeon's Appreciation of the Extent of Gastric Volume to be Removed;|Increase the Safety Profile of the Patient (i.e., Reduce the Likelihood of Accidental Stapling of the Orogastric Tube or Bougie);|Reduce the Incidence of OR Contamination/Infection Transmission;|Streamline OR Workflow, Resulting in Reduced OR Time|Ensure Consistent and Reproducible Staple Lines.
Interventions: DEVICE: Utilization of ViSiGi calibration tube|DEVICE: Usual non suction Bougie
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Neutropenic Patients With Fever Who Are Suspected to Have A Gram Positive Infection
Status: COMPLETED
Conditions: Febrile Neutropenia
Interventions: DRUG: linezolid|DRUG: vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Identifying Ideal Reimbursement "Dose" to Reduce Clinical Trial-related Financial Toxicity
Status: ENROLLING_BY_INVITATION
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Reimbursement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Anthracycline-free Taxane Based Chemotherapy in Patients With HER2/Neu Negative Early Breast Cancer
Status: COMPLETED
Conditions: Primary Breast Cancer|Her2 Non-overexpressing
Interventions: DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: Docetaxel|DRUG: Cyclophosphamide|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of ChAdV63.HIVconsv and MVA.HIVconsv Candidate HIV-1 Vaccines in Recently HIV-1 Infected Individuals
Status: COMPLETED
Conditions: HIV
Interventions: BIOLOGICAL: 0-24 week prime/boost regimen|BIOLOGICAL: 0-8 week prime/boost regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DMT310-005 Topical in the Treatment of Acne Rosacea
Status: ACTIVE_NOT_RECRUITING
Conditions: Acne Rosacea
Interventions: DRUG: Topical Powder|DRUG: Placebo Topical Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Colonoscopy Adenoma Detection Yield
Status: UNKNOWN
Conditions: Adenoma Colon
Interventions: DEVICE: Standard Colonoscopy|DEVICE: Discovery aided colonoscopy|DEVICE: Discovery and G-EYE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Ledipasvir+Sofosbuvir and Sofosbuvir+Velpatasvir for Pts With Indolent Bcell Lymphoma Associated With HCV Infection
Status: COMPLETED
Conditions: Indolent B-cell Lymphoma|Hepatitis C
Interventions: DRUG: Ledipasvir+Sofosbuvir|DRUG: Sofosbuvir+Velpatasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety and Effectiveness of XenoSure Biological Patch in the Application of Cardiac Repair
Status: RECRUITING
Conditions: Heart Diseases
Interventions: PROCEDURE: Open heart surgery to address the heart disease|DEVICE: Close the defects with XenoSure Patch|DEVICE: Close the defects with Chest Polyester Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate ABP 938 and Aflibercept (Eylea®) in Participants With Chorioretinal Vascular Disease (CVD)
Status: COMPLETED
Conditions: Chorioretinal Vascular Disease
Interventions: DRUG: ABP 938|DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Near Normalisation of BG Improves the Potentiating Effect of GLP-1
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: glucagon-like peptide-1|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Potential Benefits of Itopride in the Management of Patients With Metabolic Associated Fatty Liver Disease (MAFLD)
Status: NOT_YET_RECRUITING
Conditions: Fatty Liver Disease|Fatty Liver
Interventions: DRUG: Itopride|DRUG: conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Jedi Grip Versus Double Operator Technique For Ultrasound Guided Infraclavicular Block
Status: COMPLETED
Conditions: Ultrasound|Nerve Block
Interventions: PROCEDURE: USG guided infraclavicular block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neural Enabled Prosthesis for Upper Limb Amputees
Status: RECRUITING
Conditions: Amputation Arm and Hand, Unilateral Right|Amputation Arm and Hand, Unilateral Left|Prosthesis User
Interventions: DEVICE: Neural Enabled Prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: An Open Label Study That Compares Varenicline to Transdermal Nicotine Patch for Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: varenicline (CP-526,555)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Effect on Gametocytes and Tolerability of the Addition of Artesunate to Amodiaquine in Colombia
Status: COMPLETED
Conditions: Malaria,Falciparum|Malaria|Antimalarials
Interventions: DRUG: Artesunate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Does N-Acetylcysteine Decrease Spontaneous Oxidation of Central Neural Dopamine in Parkinson's Disease?
Status: TERMINATED
Conditions: Parkinson Disease|Cerebrospinal Fluid
Interventions: DRUG: N-Acetylcysteine|PROCEDURE: Lumbar Puncture|RADIATION: Fluoroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Post-market Clinical Investigation of the Angio-Seal™ VIP VCD (ANGIO-SEAL CLOSE)
Status: RECRUITING
Conditions: Vascular Closure|Endovascular Procedure|Hemostasis|Peripheral Vascular Disease|Femoral Artery
Interventions: DEVICE: Closure of the femoral arterial puncture site
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Enhancing Innate Anti-Viral Resistance Through A Community-Based Intervention - Generation Xchange
Status: ENROLLING_BY_INVITATION
Conditions: Virus Infection, RNA
Interventions: BEHAVIORAL: GenX intergenerational mentoring program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: AMG 531 in Patients With Advanced Malignancy Receiving Treatment With Carboplatin
Status: COMPLETED
Conditions: Solid Tumors|Advanced Cancer
Interventions: DRUG: AMG 531|DRUG: Carboplatin|DRUG: Adriamycin|DRUG: Ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial Evaluating the Safety and Efficacy of the Use of Chitosan Gel in Patients With Chronic Wounds
Status: TERMINATED
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: ChitoCare gel|DEVICE: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics for Gout / Hyperuricemia: A Randomized, Intervention, Parallel Controlled, Multicenter Clinical Trial
Status: RECRUITING
Conditions: Gout|Hyperuricemia
Interventions: DIETARY_SUPPLEMENT: Probiotics|DRUG: uric-acid-lowering drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Elagolix Versus Placebo or Leuprorelin Acetate in Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Leuprorelin Acetate Depot|DRUG: Elagolix|DRUG: Placebo to Elagolix|DRUG: Placebo to Leuprorelin Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ivermectin to Prevent Hospitalizations in COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Ivermectin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Trial of the Efficacy and Safety of a New Formulation of Ibuprofen 800 mg Every 6 Hours in the Management of Postoperative Pain
Status: TERMINATED
Conditions: Postoperative Pain
Interventions: DRUG: Intravenous ibuprofen|DRUG: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Injection Regimens of Autologous Conditioned Plasma for Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Hyaluronan|BIOLOGICAL: Autologous conditioned plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Navicixizumab Monotherapy or in Combination in Patients With Select Advanced Solid Tumors
Status: RECRUITING
Conditions: Colorectal Cancer|Triple Negative Breast Cancer|Gastric Cancer|Ovarian Cancer
Interventions: BIOLOGICAL: navicixizumab+paclitaxel|BIOLOGICAL: navicixizumab+irinotecan|BIOLOGICAL: navicixizumab monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Gabapentin on Postoperative Opioid Analgesic Use and Pain in Adolescents Undergoing Tonsillectomy
Status: TERMINATED
Conditions: Pain, Postoperative
Interventions: DRUG: Gabapentin|DRUG: hydrocodone, acetaminophen and ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tinostamustine Conditioning and Autologous Stem Cell
Status: TERMINATED
Conditions: Multiple Myeloma in Relapse|Multiple Myeloma Progression|Multiple Myeloma With Failed Remission
Interventions: DRUG: Tinostamustine|PROCEDURE: Autologous Stem Cell Transplant (ASCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Electrical Impedance Tomography in Obese Patients Undergoing Robotic Assisted Radical Prostatectomy.
Status: UNKNOWN
Conditions: Obese
Interventions: DEVICE: Electrical Impedance Tomography|DEVICE: Peripheral arterial Saturation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Delay to Diagnosis in Digestive Cancerology by the General Practitioner Related to Covid-19 Pandemic Confinement
Status: COMPLETED
Conditions: Neoplasms, Colorectal|General Practitioner|Pandemic, COVID-19|Neoplasm, Liver|Neoplasms Pancreatic|Diagnosis|Advanced Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Balanced Lifestyle for Undergraduate Excellence - Mobile (Project BLUEM)
Status: COMPLETED
Conditions: Binge Drinking|Alcohol Drinking in College|Behavior, Drinking|Behavior and Behavior Mechanisms
Interventions: BEHAVIORAL: Brief Motivational Intervention+Substance-Free Activity Session|OTHER: Alcohol + Nutrition Education Session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Test of Chamber Pressure to Divers and Chamber Attendants
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Hyperbaric Oxygen (1.5 atm abs)|DRUG: Sham Chamber Session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Helping Individuals With Firearm Injuries
Status: COMPLETED
Conditions: Wounds, Gunshot
Interventions: BEHAVIORAL: Critical Time Intervention|OTHER: Treatment as Usual|BEHAVIORAL: Motivational Interviewing|OTHER: Multi-Agency Attention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hybrid Fractional Laser for Symptoms of Genitourinary Syndrome of Menopause
Status: COMPLETED
Conditions: Vaginal Atrophy|Sexual Dysfunction|Dyspareunia|Vaginal Dryness|Chronic UTI
Interventions: DEVICE: Hybrid Fractional Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study For Patients With EGFRm (Epidermal Growth Factor Receptor Mutant) Lung Cancer
Status: WITHDRAWN
Conditions: Advanced EGFRm (Del 19 or L858R +/- T790M) NSCLC
Interventions: DRUG: PF-06459988
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect Of Dual Treatment With L-Carnitine And Magnesium On Fatty Liver
Status: UNKNOWN
Conditions: Non Alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: "slim water"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Amniotic Membrane Over Pancreatic Anastomosis After Pancreaticoduodenenctomy to Preventing Pancreatic Fistula
Status: COMPLETED
Conditions: Post Operative Pancreatic Fistula|Pancreatic Resection|Biological Dressing
Interventions: PROCEDURE: Amniotic Membrane implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: mCIMT and Eye Patching for Neglect Rehabilitation Post Stroke: A Longitudinal Study of Separate and Combined Effects
Status: UNKNOWN
Conditions: Stroke|Hemispatial Neglect
Interventions: DEVICE: mCIMT combined with or without eye patching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity Pilot
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Depression|Alcohol-Related Disorders|Suicidal Ideation|Substance-Related Disorders|Mild Cognitive Impairment|Quality of Life
Interventions: BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Cognitive Behavioral Therapy Elements|DRUG: Psychotropic Drugs|OTHER: Care Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition on Arterial Wall Inflammation in Patients With Elevated Lipoprotein(a) (Lp(a))
Status: COMPLETED
Conditions: Subjects With Hyperlipidemia, Dyslipidemia
Interventions: DRUG: Evolocumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Atropine in Laparoscopic Gynaecological Surgery
Status: UNKNOWN
Conditions: Laparoscopic Surgery|Gynecology
Interventions: DRUG: Atropine|DRUG: Placebo|DRUG: Sevoflurane|DRUG: sugammadex|DRUG: Ketorolac|DRUG: Morphine PCA|DRUG: rocuronium|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the ReLeaf Analgesic Infusion Catheter & Wound Drain
Status: WITHDRAWN
Conditions: Low Back Pain
Interventions: DEVICE: ReLeaf catheter|DRUG: Ropivacaine|DRUG: Saline|DRUG: Morphine|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety and Effect of the Experimental Drugs ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 in Subjects With Chronic Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection
Interventions: DRUG: ABT-450/r/ABT-267, ABT-333|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation Combined With Oral Feeding on Dysphagia
Status: RECRUITING
Conditions: Stroke
Interventions: BEHAVIORAL: Comprehensive rehabilitation therapy|DEVICE: Intermittent Oro-esophageal Tube Feeding|DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess ARI-3037MO on Hepatic Fat Metabolism in Patients With Dysglycemia and Evidence of Hepatic Steatosis
Status: UNKNOWN
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: Placebo|DRUG: ARI-3037MO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation Effects on Pain, Edema, Paresthesia and Bone Regeneration After Maxillar Surgical Disjunction
Status: UNKNOWN
Conditions: Maxillary Diseases
Interventions: RADIATION: Photobiomodulation|RADIATION: Placebo Photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reintegration of Children From Institutions in Azerbaijan
Status: UNKNOWN
Conditions: Emotional Trauma|Child Mental Disorder|Child Maltreatment
Interventions: BEHAVIORAL: Usual Care|BEHAVIORAL: Family Strengthening|BEHAVIORAL: Mental Health Screening, Referral and Connection to Services|OTHER: Economic Empowerment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Study of Head and Neck Cancer Radiation Treatment With or Without Amifostine
Status: WITHDRAWN
Conditions: Oral Mucositis|Stomatitis
Interventions: DRUG: Amifostine|RADIATION: Amifostine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioavailability Study of Valacyclovir HCl Tablets, 1000 mg of Dr. Reddy's Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Valacyclovir Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Multicentre Study for the Acute Relief of Episodic and Chronic Cluster Headache.
Status: COMPLETED
Conditions: Cluster Headache
Interventions: DEVICE: gammaCore
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety and Efficacy of Adipose-derived Stem Cells to Treat Complex Perianal Fistulas in Patients Participating in the FATT-1 Randomized Controlled Trial
Status: COMPLETED
Conditions: Complex Perianal Fistula
Interventions: DRUG: ASCs|DRUG: Fibrin glue|DRUG: ASCs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Electrophysiology of the Human Pituitary Gland
Status: TERMINATED
Conditions: Pituitary Adenoma|Pituitary Tumor|Diabetes Insipidus Cranial Type|Endocrine; Deficiency
Interventions: PROCEDURE: Micro-electrode measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Long-term Follow-up Study With Darvadstrocel in the Treatment of Complex Perianal Fistula
Status: COMPLETED
Conditions: Crohn's Disease|Complex Perianal Fistula
Interventions: BIOLOGICAL: Darvadstrocel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Adipose Tissue Pre and Post Bariatric Surgery
Status: UNKNOWN
Conditions: Obesity
Interventions: PROCEDURE: Bariatric surgery|OTHER: Blood sampling|OTHER: Blood pressure|OTHER: Anthropometric measurements|OTHER: Body composition|OTHER: Resting metabolic rate|OTHER: Food intake|PROCEDURE: Adipose tissue biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hypofractionated Boost Before Chemoradiation for Patients With Stage II-III Non-small Cell Lung Cancer Unsuitable for Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Non-small Cell Lung Cancer|Stage IIA Non-small Cell Lung Cancer|Stage IIB Non-small Cell Lung Cancer|Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer
Interventions: RADIATION: hypofractionated radiation therapy|DRUG: cisplatin|DRUG: etoposide|RADIATION: 3-dimensional conformal radiation therapy|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of the Proceed Ventral Patch With and Without Laparoscopic Evaluation
Status: COMPLETED
Conditions: Umbilical Hernias|Ventral Hernias
Interventions: DEVICE: Proceed Ventral Patch placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical and Refractive Outcomes of Combined Glaucoma Surgery
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension|Filtering Surgery
Interventions: PROCEDURE: phacotrabeculectomy|PROCEDURE: ExPress antiglaucoma surgery combined with phacoemulsification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Registry-Based Clinical Trial of Pimozide in Patients With Neuromuscular Junction Transmission Dysfunction Due to ALS
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: DRUG: Pimozide 2 mg per day|DRUG: Pimozide 4 mg per day|DRUG: Placebo (Lactose tablet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of R935788 Tablets to Treat Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Fostamatinib disodium (R935788)|DRUG: Fostamatinib disodium (R935788)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retention of Bonded Amalgam Sealants Versus Resin-based Sealants
Status: COMPLETED
Conditions: Incipient Enamel Caries|Fissure, Dental
Interventions: PROCEDURE: Amalgam sealant|PROCEDURE: Resin based sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Trial for the Use of a Pulsed Electromagnetic Field Device to Assist Management of Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DEVICE: Pulsed Electromagnetic Frequency Device (Energy5)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Evaluation Of Bone Width Gain Following Split Crest Technique With Or Without Platelet Rich Fibrin( PRF)
Status: COMPLETED
Conditions: Ridge Deficiency
Interventions: PROCEDURE: Split Crest with PRF|PROCEDURE: Split Crest without PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Registry Based Randomized-Controlled Trial of an Upper Limb Exergaming Intervention for Children and Adolescents With Spinal Muscular Atrophy
Status: NOT_YET_RECRUITING
Conditions: Spinal Muscular Atrophy
Interventions: OTHER: Exergaming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of LY3023414 in Participants With Advanced Cancer
Status: COMPLETED
Conditions: Advanced Cancer|Metastatic Cancer|Non-Hodgkin's Lymphoma|Metastatic Breast Cancer|Malignant Mesothelioma|Non-small Cell Lung Cancer
Interventions: DRUG: LY3023414|DRUG: Midazolam|DRUG: Fulvestrant|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Abemaciclib|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficiency Study of Pioglitazone in Combination With Imatinib Mesylate to Treat Chronic Myelogenous Leukemia
Status: UNKNOWN
Conditions: Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Interventions: DRUG: Pioglitazone|DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Two Different Regimens of Mipomersen in Patients With Familial Hypercholesterolemia and Inadequately Controlled Low-Density Lipoprotein Cholesterol
Status: COMPLETED
Conditions: Hypercholesterolemia|Heterozygous Familial
Interventions: DRUG: mipomersen sodium 200 mg|DRUG: Placebo|DRUG: mipomersen sodium 70 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 4 Study of Regorafenib in Metastatic Colorectal Cancer - Does Educating Physicians Change Patient Outcomes?
Status: TERMINATED
Conditions: Physician Education
Interventions: DRUG: Regorafenib (Stivarga, BAY73-4506)|OTHER: iPAD application|OTHER: Bayer specialist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing Maintenance of Device Mastery With Turbohaler© vs. Spiromax© in Healthcare Professionals naïve to Both Devices
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: Training on BF Spiromax followed by SYMBICORT Turbohaler|DEVICE: Training on SYMBICORT Turbohaler followed by BF Spiromax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Psychometric Properties of Kinematic Parameters of Locomotion Measured by Inertial Measurement Units. Validation in Healthy Children and Children With Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: Analysis of walking|OTHER: Analysis of running|OTHER: Analysis of walking
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Brushing With Fluoride Toothpaste on Dental Plague Control for Elementary School Students
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: 1450ppm Fluoride toothpaste|OTHER: 1000Pppm Fluoride toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Exercising Together During Radiation Treatment
Status: COMPLETED
Conditions: Domestic Partnership|Prostate Carcinoma|Spouse
Interventions: BEHAVIORAL: Exercise Intervention|OTHER: Questionnaire Administration|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunoadsorption vs. Sham Treatment in Post COVID-19 Patients With Chronic Fatigue Syndrome
Status: RECRUITING
Conditions: Fatigue|Post-Acute COVID-19 Syndrome
Interventions: PROCEDURE: Immunoadsorption vs. sham immunoadsorption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sintilimab in Combination With Gemcitabine and Platinum-Based Chemotherapy as First-Line Therapy for Advanced or Metastatic Squamous NSCLC
Status: COMPLETED
Conditions: Squamous NSCLC
Interventions: DRUG: Sintilimab|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Placebo|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Response Prediction for Anti-angiogenic Treatment in Recurrent Glioblastoma
Status: COMPLETED
Conditions: Adult Glioblastoma|Magnetic Resonance Imaging|Bevacizimab
Interventions: DIAGNOSTIC_TEST: 3-Tesla conventional magnetic resonance imaging|DIAGNOSTIC_TEST: Advanced imaging without contrast use|DIAGNOSTIC_TEST: Dynamic susceptibility contrast-weighted imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Combination Medical Therapy Followed by BPA on Right Ventricular-PA Coupling and Hemodynamics in CTEPH
Status: NOT_YET_RECRUITING
Conditions: CTEPH
Interventions: DRUG: Macitentan Tablets|DRUG: Riociguat|DEVICE: balloon pulmonary angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT