pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: ADVANCE Study: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) + Adefovir Dipivoxil in Patients With Hbe(-) Chronic Hepatitis B
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: adefovir dipivoxil|DRUG: peginterferon alfa-2a [Pegasys]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investıgatıon of The Effıciency of Pulsed Electromagnetıc Field Therapy and Stretching Exercises
Status: COMPLETED
Conditions: Muscle Injury|Pulsed Electromagnetic Therapy|Muscle Stretching Exercise
Interventions: OTHER: Exercise|DEVICE: Pulsed Electromagnetic Field Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Administration or Nasal Feeding of Huzhangxiefei Decoction for Treatment in Sepsis Induced Acute Lung Injury
Status: UNKNOWN
Conditions: Acute Lung Injury|Sepsis
Interventions: DRUG: Huzhangxiefei Decoction|DRUG: 10% Huzhangxiefei Decoction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Feeding Source on the Gut Microbiome and Time to Full Feeds in Neonates With Congenital Gastrointestinal Pathologies
Status: RECRUITING
Conditions: Gastrointestinal Complication|Intestinal Obstruction|Gastroschisis|Hirschsprung Disease|Omphalocele|Midgut Volvulus
Interventions: DIETARY_SUPPLEMENT: Standard of Care|DIETARY_SUPPLEMENT: Exclusive Human Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Omega-3 Fatty Acids in Treating Women With Newly Diagnosed Ductal Carcinoma In Situ and/or Atypical Ductal Hyperplasia
Status: COMPLETED
Conditions: Breast Cancer|Precancerous Condition
Interventions: DIETARY_SUPPLEMENT: omega-3 fatty acid|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Chemoimmunotherapy for the Treatment of Men With Neuroendocrine or Aggressive Variant Metastatic Prostate Cancer
Status: RECRUITING
Conditions: Metastatic Prostate Neuroendocrine Carcinoma|Metastatic Prostate Cancer
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|DRUG: Carboplatin|DRUG: Cabazitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association of the Arteriovenous Difference in Carbon Dioxide and Its Relation to the Difference in Arteriovenous Oxygen Content With the Occurrence of Postoperative Complication
Status: COMPLETED
Conditions: Surgery--Complications
Interventions: PROCEDURE: patient having to undergo a high risk programmed digestive surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Non-inferiority Study Comparing Two Filgrastim Preparations in Breast Cancer
Status: COMPLETED
Conditions: Neutropenia in Breast Cancer
Interventions: DRUG: Filgrastim (Eurofarma)|DRUG: Filgrastim (Granulokine, Amgen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Analgesic Efficacy of Different Doses of Sucrose During Blood Sampling in Preterm Infants
Status: UNKNOWN
Conditions: Pain
Interventions: DIETARY_SUPPLEMENT: sucrose 24%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Perceptual Distortions in Acute Neck Pain
Status: COMPLETED
Conditions: Neck Pain, Posterior|Pain, Acute
Interventions: OTHER: Saline injection|OTHER: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Acarbose on Abnormal Glucose Regulation in Patients With Coronary Artery Disease (AAA Trial)
Status: UNKNOWN
Conditions: Diabetes Mellitus|Impaired Glucose Tolerance|Coronary Artery Disease
Interventions: DRUG: acarbose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Effect of Left Tilting in Cesarean Delivery
Status: UNKNOWN
Conditions: Cesarean Section Complications|Spinal Anesthetic Complications
Interventions: OTHER: left lateral tilting in 15 degrees|OTHER: left lateral tilting in 30 degrees|OTHER: supine position
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Body Mass Index on Thoracic Paravertebral Block Analgesia
Status: COMPLETED
Conditions: Pain, Postoperative|Acute Pain|Thoracic Paravertebral Block|Body Mass Index|Thoracic Surgery, Video-Assisted
Interventions: PROCEDURE: Thoracic Paravertebral Block
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Insomnia in Patients With Low Back Pain
Status: COMPLETED
Conditions: Primary Insomnia
Interventions: DRUG: Eszopiclone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Selinexor Treatment for Multiple Myeloma Patients Who Are Refractory to Lenalidomide-containing Therapy.
Status: RECRUITING
Conditions: Refractory Multiple Myeloma
Interventions: DRUG: Selinexor|DRUG: Lenalidomide|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: THE USE OF N-ACETYLCYSTEINE ATTENUATING CISPLATIN-INDUCED TOXICITIES BY OXIDATIVE STRESS
Status: UNKNOWN
Conditions: Head and Neck Neoplasms
Interventions: DRUG: N-acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Effectiveness of BM-MSC vs AT-MSC in the Treatment of SCI Patients.
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: BIOLOGICAL: Autologous Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Optimal Timing of Carbon Dioxide Insufflation During Colonoscopy in Unsedated Patients
Status: COMPLETED
Conditions: Outpatients
Interventions: PROCEDURE: Insufflation with CO2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pilot Study of Femring Estrogen Supplementation During Depo-Provera Initiation
Status: COMPLETED
Conditions: Metrorrhagia
Interventions: DRUG: Femring®|DRUG: DepoProvera ®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of C-type Natriuretic Peptide on Human Forearm Blood Vessels
Status: WITHDRAWN
Conditions: Ischaemia-reperfusion (IR) Injury
Interventions: DRUG: C-type natriuretic peptide (CNP)|DRUG: Saline|DRUG: Acetylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Standard Therapy Using Tacrolimus, Mycophenolate Mofetil and Prednisone For Chronic Lung Transplant Rejection (BOS)
Status: WITHDRAWN
Conditions: Disorder Related to Lung Transplantation|Chronic Rejection of Lung Transplant|Decreased Immunologic Activity
Interventions: DRUG: Assigned Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Laser Therapy on Tension-type Cephalea and Orofacial Pain in Post-covid-19 Patients
Status: UNKNOWN
Conditions: Tension-Type Headache|Orofacial Pain|COVID-19
Interventions: RADIATION: Photobimodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-treatment With Methylene Blue Prevent Peri-operative Reduced Systemic Vascular Resistance
Status: UNKNOWN
Conditions: Obstructive Jaundice
Interventions: DRUG: Methylene Blue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Chemotherapy Plus Sargramostim in Treating Patients With Refractory Myeloid Cancer
Status: COMPLETED
Conditions: Accelerated Phase Chronic Myelogenous Leukemia|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Blastic Phase Chronic Myelogenous Leukemia|Chronic Myelomonocytic Leukemia|Chronic Phase Chronic Myelogenous Leukemia|Paroxysmal Nocturnal Hemoglobinuria|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Myeloid Leukemia|Refractory Anemia|Refractory Anemia With Ringed Sideroblasts|Relapsing Chronic Myelogenous Leukemia|Thrombocytopenia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: bryostatin 1|BIOLOGICAL: sargramostim|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bladder Instillations Versus Onabotulinumtoxin A for Treatment of Interstitial Cystitis/Bladder Pain Syndrome
Status: COMPLETED
Conditions: Interstitial Cystitis|Bladder Pain Syndrome
Interventions: DRUG: Heparin & Alkalinized Lidocaine Bladder Instillation|DRUG: Onabotulinum Toxin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects Of DBS Of Subthalamıc Nucleus On Functionality In Patıents With Parkinson's Disease: Short-Term Results
Status: UNKNOWN
Conditions: Parkinson Disease|Surgery|Respiration; Decreased|Muscle Weakness
Interventions: DEVICE: MIP and MEP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Omega-3 Fatty Acids (Lovaza) for Second Generation Antipsychotic-Associated Hypertriglyceridemia
Status: COMPLETED
Conditions: High Triglycerides|Hypercholesterolemia|Schizophrenia|Schizoaffective Disorder|Bipolar Disorder
Interventions: DRUG: Lovaza
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Brief Cognitive Task Intervention for NHS Staff Affected by COVID-19 Trauma (GAINS-2 Study)
Status: COMPLETED
Conditions: Intrusive Memories of Traumatic Event(s)
Interventions: BEHAVIORAL: Brief digital imagery-competing task|BEHAVIORAL: Brief digital music-listening task|OTHER: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Endobronchial Ultrasound Sampling for Molecular Markers for NSCLC
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer|Non Small Cell Lung Cancer|Circulating Tumor Cell
Interventions: PROCEDURE: Endobronchial ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Tension Versus Tension- Free Foley Balloon for Cervical Ripening
Status: ACTIVE_NOT_RECRUITING
Conditions: Induced Vaginal Delivery
Interventions: OTHER: Placement of Foley balloon for cervical ripening with tension.|OTHER: Placement of Foley balloon for cervical ripening without tension.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomised Trial of ATRA in a Novel Drug Combination for Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: ATRA|DRUG: Gemcitabine|DRUG: nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peng Block or Suprascapular Nerve Block for Postoperative Analgesia in Shoulder Artroscopy ?
Status: RECRUITING
Conditions: Orthopedic Disorder|Shoulder Pain|Surgery|Analgesia
Interventions: PROCEDURE: Pericapsular nerve block|PROCEDURE: Suprascapular nerve block|DRUG: Bupivacaine and prilocaine hydrochloride|DRUG: Bupivacaine and prilocaine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Naturalistic Trial of Nudging Clinicians in the Norwegian Sickness Absence Clinic. The NSAC Nudge Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Musculoskeletal Disorder|Anxiety Disorders|Depression|Fatigue|Pain|Occupational Exposure|Work Related Stress|Workplace Bullying|Employment|Sickness Absence|Return to Work
Interventions: OTHER: NSAC health only|OTHER: NSAC health + MBW
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Lowering Dietary Carbohydrates on Health, Exercise Performance and Wellbeing-related Outcomes
Status: COMPLETED
Conditions: Obesity|Diet Modification
Interventions: BEHAVIORAL: Ketogenic diet|BEHAVIORAL: Exercise HIIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of Blinded Tapering for Hypnotic Discontinuation
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypnotic Dependence Among Those With Insomnia
Interventions: BEHAVIORAL: Hypnotic Medication Open-Label Taper|BEHAVIORAL: Hypnotic Medication Blinded Taper
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Balance Control and Recovery in Diabetes Peripheral Neuropathy
Status: RECRUITING
Conditions: Diabetic Peripheral Neuropathy|Diabetic Peripheral Neuropathy Type 2|Diabetic Peripheral Neuropathy Type 2 - Uncontrolled|Healthy Aging
Interventions: BEHAVIORAL: sit-to-stand|BEHAVIORAL: stand to sit|BEHAVIORAL: standing perturbation|OTHER: MRI of sciatic nerve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Demonstrate the Safety and Efficacy of Siplizumab in the Treatment of Hidradenitis Suppurativa
Status: NOT_YET_RECRUITING
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Siplizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fistulotomy Versus Fistulotomy With Marsupialization
Status: COMPLETED
Conditions: Fistula in Ano
Interventions: PROCEDURE: standard fistulotomy|PROCEDURE: fistulotomy with marsupialization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Doxorubicin/Cyclophosphamide Followed by Eribulin Chemotherapy (ACE) in Operable HER2-negative Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Eribulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Radiotherapy on Oligometastatic Cancer
Status: RECRUITING
Conditions: Metastasis|Metastatic Breast Cancer|Metastatic Prostate Cancer|Metastatic Colorectal Cancer|Metastatic Lung Cancer
Interventions: DIAGNOSTIC_TEST: To propose a diagnostic test to determine the viability of Stereotactic ABlative Radiotherapy (SABR).|DIAGNOSTIC_TEST: To propose a diagnostic test to determine the effectiveness of SABR.|DIAGNOSTIC_TEST: To propose a diagnostic test for Oligometastatic Cancer (OC).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Apidra Compared to Humalog in Decreasing Post-Prandial Hyperglycemia
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Apidra|DRUG: Humalog|DRUG: Novolog
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Raltegravir in Patients With End Stage Liver Disease and in Transplant Recipients
Status: COMPLETED
Conditions: HIV Infection|Liver Failure|Evidence of Liver Transplantation
Interventions: DRUG: Raltegravir potassium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients With PD1-high mRNA Expressing Tumors
Status: RECRUITING
Conditions: MSI-H Colorectal Cancer|Melanoma|Anal Carcinoma|Mesothelioma|Triple Negative Breast Cancer|Lung Adenocarcinoma|Cholangiocarcinoma|Cervical Carcinoma|Kidney Clear Cell Carcinoma|Stomach Adenocarcinoma|Esophageal Adenocarcinoma|Uterine Adenocarcinoma|Head and Neck Squamous Cell Carcinoma|Sarcoma|Lung Squamous Cell Carcinoma|Urothelial Carcinoma|Thyroid Carcinoma|Hepatocellular Carcinoma|Uveal Melanoma|HER2-positive Breast Cancer|Pancreatic Adenocarcinoma|Squamous Esophageal Carcinoma|Epithelial Ovarian Cancer|Uterine Carcinosarcoma|Small Cell Lung Cancer|Hormone Receptor Positive / HER2-negative Breast Cancer|Lung Adenocarcinoma EGFR-mutated/ ALK Traslocation|Colorectal Adenocarcinoma|Prostate Adenocarcinoma|Carcinoma of Unknown Primary|Other Histology
Interventions: DRUG: Spartalizumab|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resynchronization for Ambulatory Heart Failure Trial - LV Endocardial
Status: TERMINATED
Conditions: Heart Failure, Left Ventricular Dysfunction
Interventions: DEVICE: Conventional CRT|DEVICE: LV endocardial CRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Computer-assisted Template-based Implant Placement Using Conventional or Digital Impression
Status: UNKNOWN
Conditions: Dental Implant Failure
Interventions: PROCEDURE: Conventional impressions|PROCEDURE: Digital impressions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ciclosporin in the Management of Chronic or Recurrent Erythema Nodosum Leprosum
Status: COMPLETED
Conditions: Leprosy
Interventions: DRUG: prednisolone|DRUG: ciclosporin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SCIPA Full-On :Intensive Exercise Program After Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DEVICE: Therastride Treadmill System|DEVICE: FES-assisted cycling|OTHER: Trunk and upper and lower limb exercises|OTHER: Upper body strength and fitness program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STARZ-TX2 Clinical Study: Study of Thoracic Aortic Aneurysm Repair With the Zenith TX2 Endovascular Graft
Status: COMPLETED
Conditions: Thoracic Aortic Aneurysm
Interventions: DEVICE: Endovascular repair|PROCEDURE: Surgical
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intracoronary Administration of OmniMSC-AMI for Acute ST-segment Elevation Myocardial Infarction Patients
Status: RECRUITING
Conditions: Safety Issues
Interventions: BIOLOGICAL: OmniMSC-AMI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temperature Sensitive Release of PGE2 and Diminished Energy Requirements in Synovial Tissue With Postoperative Cryotherapy - A Prospective Randomised Study After Knee Arthroscopy
Status: COMPLETED
Conditions: Knee Arthroscopy|Meniscus|Inflammation|Hydrops|Cooling
Interventions: DEVICE: Cooling and compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prehabilitation and Coronary Artery Bypass Grafting
Status: COMPLETED
Conditions: Coronary Artery Bypass Graft
Interventions: OTHER: Resistant training (Prehabilitation)|OTHER: Active Comparator: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects Of Anticholinergic Burden On Daily Living Activities In Elderly Patients
Status: NOT_YET_RECRUITING
Conditions: Anticholinergic Syndrome|Anticholinergic Adverse Reaction|Antispasmodic Adverse Reaction|Antiarrhythmic Drug Adverse Reaction|Antiparkinsonism Drugs Causing Adverse Effects in Therapeutic Use|Psychotropic Agents Causing Adverse Effects in Therapeutic Use
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Effects of Cerefolin NAC on Inflammation Blood Markers in Older Individuals With Memory Complaints
Status: COMPLETED
Conditions: Subjective Memory Loss in Older Persons
Interventions: OTHER: Cerefolin NAC (a medical food)|OTHER: Cerefolin NAC placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PROMISE Study: An Evaluation of an Implantable Continuous Glucose Sensor up to 180 Days
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DEVICE: Continuous Glucose Monitoring System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Rebalancing Thoraco Abdominal Heart Disease in Infants (RTAC)
Status: COMPLETED
Conditions: Infants With Heart Disease|Respiratory Therapy|Techniques
Interventions: PROCEDURE: Thoracoabdominal rebalancing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mask Adhesive Institutional Study
Status: TERMINATED
Conditions: Respiratory Failure|Covid19
Interventions: DEVICE: Mask with Mask Adhesive/Arm 1|DEVICE: Mask without Mask Adhesive / Arm 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Effect of Chlorhexidine Mouthwash After Periodontal Surgery
Status: UNKNOWN
Conditions: Periodontal Diseases|Periodontitis|Dental Plaque
Interventions: DRUG: Chlorhexidine 0.2%, Corsodyl|DRUG: Chlorhexidine 0.2%, Curasept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AZD0530 and Gemcitabine in Locally Advanced/Metastatic Pancreatic Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: AZD0530|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Surgery in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: doxorubicin hydrochloride|DRUG: ifosfamide|DRUG: leucovorin calcium|DRUG: methotrexate|DRUG: trimetrexate glucuronate|PROCEDURE: surgical procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of AL2846 Versus Zoledronic Acid in Subjects With Advanced Non-Small Cell Lung Cancer With Bone Metastasis
Status: UNKNOWN
Conditions: Bone Metastatic Non-small Cell Lung Cancer
Interventions: DRUG: AL2846|DRUG: Zoledronic Acid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence and Effect of Lifestyle Modification on Clinical Outcomes and Cost-effectiveness Ratio for Sarcopenia
Status: UNKNOWN
Conditions: Sarcopenia
Interventions: BEHAVIORAL: nutritional intervention|BEHAVIORAL: resistance training program|BEHAVIORAL: lifestyle modification project|BEHAVIORAL: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Interventional, Confirmative, Post Marketing Clinical Followup (PMCF) Study to Evaluate Performance and Safety of Ophthalmic Solutions Used to Relieve Dry Eyes Like Symptoms in Glaucoma Patients.
Status: RECRUITING
Conditions: Opthalomology/Dry Eye
Interventions: DEVICE: Afomill Refreshing Soothing, Afomill Anti-redness Eye Drops, Iridil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pilot Study of a Suprachoroidal Retinal Prosthesis
Status: COMPLETED
Conditions: Retinitis Pigmentosa|Choroideremia
Interventions: DEVICE: Prototype wide view suprachoroidal retinal prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BioFLO for Respiratory Recovery in SCI
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: OTHER: Acute Intermittent Hypoxia (AIH)|OTHER: Acute Intermittent Hypercapnic-Hypoxia (AIHH)|OTHER: Sham AIH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Timeliness of Immunization and Compliance Assessment Study
Status: COMPLETED
Conditions: Vaccinations
Interventions: BEHAVIORAL: Standard Compliance-linked incentives|BEHAVIORAL: Intelligent Compliance-linked incentives|OTHER: Record keeping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Post Operative Hemodynamic Function After Anesthetic Induction With Etomidate for Cardiac Surgery With ECC
Status: COMPLETED
Conditions: Cardiac Surgery
Interventions: DRUG: etomidate|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Microneedle Patch for Psoriatic Plaques
Status: UNKNOWN
Conditions: Psoriasis|Administration, Topical
Interventions: DEVICE: Microneedle HA patch|DEVICE: Patch|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Tenofovir Disoproxil Fumarate Versus Adefovir Dipivoxil for the Treatment of HBeAg-Negative Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: TDF|DRUG: ADV|DRUG: TDF placebo|DRUG: ADV placebo|DRUG: FTC/TDF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Open Label Comparison of Ezetimibe, Niacin, and Colestipol as Adjunct Therapy in Lipid Reduction
Status: COMPLETED
Conditions: Hyperlipidemia|Hypercholesterolemia
Interventions: DRUG: Niacin|DRUG: Colestipol|DRUG: Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Vitamin C on opioïd Consumption After an Emergency Department Visit for Acute Musculoskeletal Pain
Status: RECRUITING
Conditions: Pain, Acute
Interventions: DIETARY_SUPPLEMENT: Vitamin C|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Role of Subcutaneous Negative Pressure Suction Drain Placed for Ten Days on Wound Healing in Obese Patients Undergoing Midline Laparotomies
Status: COMPLETED
Conditions: Postoperative Wound Healing
Interventions: PROCEDURE: Subcutaneous negative suction drain for 10 days|PROCEDURE: No subcutaneous drain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Protein Intake and Exercise-induced Muscle Damage
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: whey protein supplement|DIETARY_SUPPLEMENT: mixed plant-based protein supplement|OTHER: e-health application|DIETARY_SUPPLEMENT: isocaloric carbohydrate control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Transfusion of Older Stored Red Cells
Status: TERMINATED
Conditions: Sickle Cell Disease|Thalassemia
Interventions: PROCEDURE: Transfusion|BIOLOGICAL: Blood|PROCEDURE: Chelation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Culturally-Specific Video Text Cessation Intervention With AA Quitline Callers
Status: COMPLETED
Conditions: Tobacco Use Cessation
Interventions: BEHAVIORAL: Path2Quit - culturally specific text message intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Natural Ingredient to Improve the Swallowing Response of Patients With Oropharyngeal Dysphagia
Status: COMPLETED
Conditions: Dysphagia
Interventions: OTHER: cinnamon extract|OTHER: lemon extract|OTHER: lemon extract plus eucalyptus extract|OTHER: Thicken Up clear: TUC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of a Capsule-Conjugate Vaccine to Prevent Campylobacter-Caused Diarrhea
Status: COMPLETED
Conditions: Campylobacter Infection
Interventions: BIOLOGICAL: Capsule-Conjugate Campylobacter Vaccine (CJCV1)|DRUG: Alhydrogel®, aluminum hydroxide adjuvant (alum)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lifestyle Intervention for Improving Insulin Resistance and Concern for Health
Status: RECRUITING
Conditions: Insulin Sensitivity|Apathy
Interventions: OTHER: Diet without soy|OTHER: Diet with soy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: External Beam Radiation Therapy and Brachytherapy With Chemotherapy and Immunotherapy for the Treatment of Stage IVB Cervical Cancer
Status: NOT_YET_RECRUITING
Conditions: Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Cervical Squamous Cell Carcinoma|Stage IVB Cervical Cancer American Joint Committee on Cancer (AJCC) v8
Interventions: BIOLOGICAL: Bevacizumab|PROCEDURE: Biospecimen Collection|RADIATION: Brachytherapy|DRUG: Cisplatin|RADIATION: External Beam Radiation Therapy|DRUG: Paclitaxel|BIOLOGICAL: Pembrolizumab|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cotrimoxazole Versus Vancomycin for Invasive Methicillin-resistant Staphylococcus Aureus Infections
Status: COMPLETED
Conditions: Staphylococcal Infections|Meningitis|Sepsis|Pneumonia
Interventions: DRUG: Cotrimoxazole|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotine Substitute Prescribed at Hourly Intake or ad Libitum for Heavy Smokers Willing to Quit
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Nasal Spray Nicotine Substitute (Experimental)|DRUG: Nasal Spray Nicotine Substitute (ad libitum)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tipifarnib in Treating Patients With Anemia or Neutropenia and Large Granular Lymphocyte Leukemia
Status: TERMINATED
Conditions: Stage III Chronic Lymphocytic Leukemia|Stage IV Chronic Lymphocytic Leukemia|T-cell Large Granular Lymphocyte Leukemia
Interventions: DRUG: tipifarnib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness and Safety of Tapentadol (CG5503) Extended Release (ER) in Patients With Moderate to Severe Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: tapentadol (CG5503) ER|DRUG: oxycodone CR|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Addition of Paclitaxel to High-Dose Combination Chemotherapy in Treating Patients With High-Risk Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: mesna|DRUG: paclitaxel|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety and Immune Response of Novartis MenACWY-CRM Conjugate Vaccine When Given to Healthy Toddlers
Status: COMPLETED
Conditions: Meningococcal Infections
Interventions: BIOLOGICAL: MenACWY-CRM + MMRV|BIOLOGICAL: MMRV|BIOLOGICAL: MenACWY-CRM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Enzymatic Versus (vs) Autolytic Debridement of Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcers
Interventions: DRUG: Santyl|DRUG: Tegaderm Hydrogel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mass Balance Recovery, Pharmacokinetics and Metabolite Profile and Identification of [14C]AZD7594
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Intravenous Infusion|DRUG: Inhaled dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers Predicting Successful Tacrolimus Withdrawal and Everolimus (Zortress) Monotherapy Early After Liver Transplantation
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DRUG: Tacrolimus Withdrawal and Everolimus Monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suprachoroidal Visco-buckling for the Treatment of Rhegmatogenous Retinal Detachment
Status: RECRUITING
Conditions: Retinal Detachment With Break
Interventions: PROCEDURE: Pars plana vitrectomy, laser or cryo retinopexy and intraocular gas tamponade|DEVICE: Suprachoroidal viscobuckle with 2.3% Sodium hyaluronate (Healon 5 Ophthalmic viscoelastic device)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zinc Absorption From Zinc Citrate, Zinc Gluconate and Zinc Oxide
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: zinc citrate|DIETARY_SUPPLEMENT: Zinc Gluconate|DIETARY_SUPPLEMENT: Zinc oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Serum Serotonin and Pruritus After Intrathecal Morphine in Cesarean Section
Status: COMPLETED
Conditions: Pruritus
Interventions: DRUG: Morphine 100 μg|DRUG: Morphine 200 μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Intravascular Fluid Resuscitation and Whole Blood Viscosity for Colon Surgery
Status: UNKNOWN
Conditions: Colon Surgery
Interventions: DRUG: Intravenous Crystalloid|DRUG: Intravenous HES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Empagliflozin in GSD1b Patients With Neutropenia
Status: NOT_YET_RECRUITING
Conditions: Glucose 6 Phosphatase Deficiency
Interventions: DRUG: Empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuronal and Behavioral Effects of Implicit Priming in Obese Individuals
Status: COMPLETED
Conditions: Feeding Behavior|Obesity|Overweight
Interventions: BEHAVIORAL: Active Implicit Priming|BEHAVIORAL: Control Implicit Priming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Atezolizumab Compared With Docetaxel in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Failed Platinum-Containing Therapy
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: Atezolizumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CHIMERIC ANTIGEN RECEPTOR TREATMENT TARGETING CD70 (SEVENTY)
Status: NOT_YET_RECRUITING
Conditions: Leukemia, Myeloid, Acute|Leukemia, B-cell|Leukemia, T-Cell|Lymphoma
Interventions: BIOLOGICAL: Treatment Arm A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Peri-surgical Results at Short and Mean Terms of the GORE ® Excluder Iliac Branch Endoprosthesis
Status: TERMINATED
Conditions: Iliac Aneurysm
Interventions: DEVICE: ILIAC ENDOPROSTHESIS GORE EXCLUDER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phenotypic and Genotypic Characterization of Patients With Dysmetabolism in Greenland
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Obesity, Morbid|Obstructive Sleep Apnea|MODY|Diabetic Retinopathy|Diabetic Neuropathies
Interventions: GENETIC: Whole genome sequencing|DIAGNOSTIC_TEST: VAGUS|DIAGNOSTIC_TEST: NightOwl|DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Atopic Dermatitis (AD) Internet Survey
Status: WITHDRAWN
Conditions: Atopic Dermatitis
Interventions: BEHAVIORAL: Weekly Internet survey|DRUG: Topical Triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Darunavir and Rilpivirine Interactions With Levonorgestrel Implant
Status: UNKNOWN
Conditions: HIV-1-infection|Contraception
Interventions: DRUG: Levonorgestrel two rod sub-dermal implant|DRUG: Rilpivirine|DRUG: Darunavir+Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient-Assisted Compression in 3D - Impact on Image Quality and Workflow
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: Patient-Assisted Compression (PAC)|DEVICE: Technologist-Controlled (TC) Compression
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Improving Emotion Regulation at the End of Breast Cancer Treatment
Status: COMPLETED
Conditions: Breast Cancer|Emotional Disturbances|Emotional Dysfunction|Anxiety Depression|Fear of Cancer
Interventions: BEHAVIORAL: Cognitive-Behavioral Group Therapy and Hypnosis|BEHAVIORAL: Cognitive-Behavioral Group Therapy and Hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating Myocardial Ischemia in Chest Pain Using Exercise CMR
Status: RECRUITING
Conditions: Ischemic Heart Disease|Coronary Artery Disease|Cardiovascular Diseases|Myocardial Ischemia|Coronary Heart Disease|Microvascular Coronary Artery Disease
Interventions: OTHER: Cardiovascular Magnetic Resonance Imaging with Exercise Bike|PROCEDURE: Cardiac Catheterization|OTHER: Retinal Photography (Optional)|DIAGNOSTIC_TEST: I123 MIBG Scintigraphy (Optional)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Postoperative Concurrent Chemoradiotherapy Combined With Endostar for High-risk Early Stage Cervical Cancer
Status: RECRUITING
Conditions: Uterine Cervical Neoplasms
Interventions: COMBINATION_PRODUCT: Chemoradiotherapy+ Endostar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation of Orthodontic Mini-implants by a 635nm Diode Laser
Status: COMPLETED
Conditions: Malocclusion, Angle Class II
Interventions: PROCEDURE: Irradiation of implants with 635nm laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation for the Evaluation of Efficacy and Safety of Two Medical Devices for Onychomycosis Treatment
Status: NOT_YET_RECRUITING
Conditions: Onychomycosis
Interventions: DEVICE: Forte|DEVICE: Active Cover Light|DRUG: Loceryl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Arm Study of Ipilimumab Monotherapy in Patients With Previously Treated Unresectable Stage III or IV Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: ipilimumab (MDX-010, BMS-734016)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ficlatuzumab With High Dose Cytarabine in Relapsed and Refractory AML
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Relapsed Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Ficlatuzumab|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Non-interventional Study to Describe the Dupilumab Long-term Treatment, Safety and Patient Reported Outcomes in Chronic Nodular Prurigo (Prurigo Nodularis) in Clinical Routine
Status: RECRUITING
Conditions: Prurigo Nodularis
Interventions: DRUG: Dupilumab SAR231893 (REGN668)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Examination of Trunk and Lower Extremity Biomechanics in Children With LUTD.
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms|Posture Disorders in Children|Muscle Weakness Condition|Urinary Incontinence in Children|Lower Extremity Problem
Interventions: OTHER: The same evaluation methods were used for both groups.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Epidural Labor Analgesia With Esketamine on the Incidence of Postpartum Depression in Parturients
Status: RECRUITING
Conditions: Postpartum Depression
Interventions: DRUG: Esketamine|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peer Intervention to Link Overdose Survivors to Treatment (PILOT)
Status: COMPLETED
Conditions: Opioid Overdose
Interventions: BEHAVIORAL: Peer Intervention to Link Overdose Survivors to Treatment (PILOT) Peer|BEHAVIORAL: Treatment As Usual Peer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE Trial
Status: RECRUITING
Conditions: Glioblastoma, IDH-Wildtype
Interventions: PROCEDURE: Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging|OTHER: Fluciclovine F18|DRUG: Gadolinium-Chelate|PROCEDURE: Magnetic Resonance Spectroscopy|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Postoperative Chemotherapy With/Without Radiotherapy and Immunotherapy for Colorectal Liver Metastases With High Risk of Locally Recurrence
Status: RECRUITING
Conditions: Radiotherapy|Immunotherapy|Liver Metastases|Colorectal Cancer
Interventions: RADIATION: SBRT|DRUG: Chemotherapy|DRUG: PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Neuromuscular Electrical Stimulation Improve the Absolute Walking Distance in Patients With Intermittent Claudication Compared to Best Available Treatment?
Status: COMPLETED
Conditions: Intermittent Claudication|Peripheral Vascular Diseases
Interventions: DEVICE: NMES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE