pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Phase 1 Study of Pegilodecakin (LY3500518) in Participants With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma|Prostate Cancer|Ovarian Cancer|Renal Cell Carcinoma|Colorectal Carcinoma|Pancreatic Carcinoma|Non-small Cell Lung Carcinoma|Solid Tumors|Breast Cancer
Interventions: DRUG: Pegilodecakin|DRUG: Paclitaxel or Docetaxel and Carboplatin or Cisplatin|DRUG: FOLFOX (Oxaliplatin/Leucovorin/5-Fluorouracil)|DRUG: gemcitabine/nab-paclitaxel|DRUG: Capecitabine|DRUG: Pazopanib|DRUG: Pembrolizumab|DRUG: Paclitaxel|DRUG: nivolumab|DRUG: Gemcitabine/carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment Effects After Direct Acting Antiviral in Chronic Hepatitis c Virus Patients
Status: UNKNOWN
Conditions: Chronic Hepatitis c
Interventions: DRUG: Sofosbuvir , daclatasvir|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Arm Retraction on the Supraclavicular Approach for Subclavian Vein Catheterization
Status: COMPLETED
Conditions: Subclavian Venous Catheterization
Interventions: PROCEDURE: arm retraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Effect of Coleus Forskohlii Extract on the Risk Factors of Metabolic Syndrome
Status: UNKNOWN
Conditions: Metabolic Syndrome|Obesity
Interventions: DIETARY_SUPPLEMENT: Coleus forskohlii extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Online Emotional Response to Completing a Childhood Maltreatment Self-report Scale
Status: COMPLETED
Conditions: Stress, Psychological|Stress, Emotional
Interventions: BEHAVIORAL: Maltreatment and Abuse Chronology of Exposure Scale as a stress challenge|BEHAVIORAL: Standardized Maths and Verbal Questions such as the ones used in SATs|BEHAVIORAL: Chronology of Perceived Discrimination Scale (CPDS)|BEHAVIORAL: International Personality Item Pool (IPIP-NEO)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nivolumab Plus Chemoradiotherapy in Patients With Muscle-invasive Bladder Cancer (MIBC) Not Undergoing Cystectomy
Status: UNKNOWN
Conditions: Bladder Cancer
Interventions: BIOLOGICAL: Nivolumab|OTHER: chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ferric Carboxymaltose With or Without Phosphate Substitution for the Treatment of Iron Deficiency or Iron Deficiency Anemia
Status: COMPLETED
Conditions: Anemia|Iron-deficiency|Hypophosphatemia
Interventions: DRUG: Verum|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Monitored vs Standard Supplementation of Vitamin D in Preterm Infants
Status: COMPLETED
Conditions: Vitamin D Deficiency|Osteopenia|Nephrolithiasis|Drug Overdose
Interventions: DIETARY_SUPPLEMENT: monitored vit D supplementation|DIETARY_SUPPLEMENT: standard vit D supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioavailability of Lacidipine and Telmisartan Fixed Dose Combination Tablets Relative to Separate Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lacidipine and Telmisartan fixed dose combination (FDC) tablet|DRUG: Lacidipine|DRUG: Telmisartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In Vivo Characterization of Macrophages in Pediatric Patients With Malignant Brain Tumors Using Ferumoxytol-enhanced MRI
Status: WITHDRAWN
Conditions: Childhood Brain Neoplasm
Interventions: DIAGNOSTIC_TEST: Diagnostic (ferumoxytol-enhanced MRI)|PROCEDURE: Surgery|DRUG: Ferumoxytol|OTHER: Tissue Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cost-effectiveness and Safety of the CADScorSystem in Patients With Symptoms Suggestive of Stable Coronary Artery Disease.
Status: COMPLETED
Conditions: Angina, Stable
Interventions: DEVICE: CADScor®System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Evaluation of the Magnesium Absorption Kinetics in Human Plasma Upon Oral Intake of Magnesium-based Products
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Dietary supplementation with Microencapsulated Magnesium|DIETARY_SUPPLEMENT: Dietary supplementation with Magnesium Oxide|DIETARY_SUPPLEMENT: Dietary supplementation with Magnesium Citrate|DIETARY_SUPPLEMENT: Dietary supplementation with Magnesium Bisglycinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Collaborative Initial Glaucoma Treatment Study (CIGTS)
Status: UNKNOWN
Conditions: Open-Angle Glaucoma
Interventions: DRUG: Beta Blocker|PROCEDURE: Trabeculectomy|PROCEDURE: Argon Laser Trabeculoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effects of Zinc Di-(Dibutyryl Lisinate) on Skin Health and the Skin Microbiome in Photoaged Skin
Status: NOT_YET_RECRUITING
Conditions: Photoaging
Interventions: OTHER: Topical Vehicle + Zinc Di-(dibutyryl lisinate)|OTHER: Topical Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Does Improved Ability to Achieve Single Leg Stance Lead to a More Efficient Gait Pattern in Adults With Acquired Brain Injury?
Status: COMPLETED
Conditions: Acquired Brain Injury
Interventions: OTHER: single leg stance treatment|OTHER: Usual physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Clinical Trial Comparing Oncological Results and Functional Recovery Between Laparoscopic and Open Method for the Treatment of Advanced Rectal Cancer After Concurrent Chemoradiation Therapy (CCRT)
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: PROCEDURE: Laparoscopic surgery|PROCEDURE: Traditional open surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anticoagulant Treatments and Percutaneous Coronary Angioplasty
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DRUG: clopidogrel + aspirin|DRUG: heparin + clopidogrel + aspirin|DRUG: enoxaparin + clopidogrel + aspirin|DRUG: bivalirudin + clopidogrel + aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Hepatitis C Treatment for Indolent Lymphoma (OPTImaL) Study
Status: TERMINATED
Conditions: Liver Disease
Interventions: DRUG: sofosbuvir/ledipasvir|DRUG: sofosbuvir|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vortioxetine for the Treatment of Major Depression and Co-morbidities After Traumatic Brain Injury (TBI)
Status: WITHDRAWN
Conditions: TBI|Major Depression
Interventions: DRUG: Vortioxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IIa L-serine Trial for eAD
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DRUG: L-Serine|OTHER: Placebo Gummy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Cognitive Behavioural Therapy for Psychosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Psychotic Disorders|Schizophrenia
Interventions: BEHAVIORAL: Virtual Cognitive Behavioural Therapy for Psychosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Trial of Intra-Tumoral Injection of NIS Measles Virus in Combination With Atezolizumab
Status: TERMINATED
Conditions: Recurrent Non-Small Cell Lung Cancer
Interventions: BIOLOGICAL: MV-NIS|BIOLOGICAL: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double-Blind, Placebo-Controlled Study to Evaluate 3 Doses of a Novel Tetracycline in the Treatment of Facial Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: 50 mg P005672-HCl|DRUG: Placebo|DRUG: 100 mg P005672-HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Hall Technique and Atraumatic Restorative Treatment for Management of Caries in the Primary Dentition
Status: COMPLETED
Conditions: Primary Dental Caries
Interventions: OTHER: Hall technique|OTHER: Atraumatic restorative treatment|OTHER: Conventional restorative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effects of Silymarin in Patients With B-thalassemia Major
Status: UNKNOWN
Conditions: Beta-thalassemia Major|Iron Overload
Interventions: DRUG: Silymarin (LEGALON)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Physical Therapy Intervention in Cervical Angina Patients at Jerash University Office Employees, "Randomized Clinical Trail".
Status: NOT_YET_RECRUITING
Conditions: Cervical Radiculopathy
Interventions: OTHER: Manual physiotherapy intervention( cervical traction, suboccipital release, muscle energy technique)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Study of Conservative Treatment of Granulomatous Lobular Mastitis Combined With Psychiatric Disorders
Status: ENROLLING_BY_INVITATION
Conditions: Breast Diseases|Mastitis Granulomatous|Psychiatric Disorder
Interventions: DRUG: conservative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Patient -Ventilator Interaction in Chronic Respiratory Failure
Status: COMPLETED
Conditions: Chronic Hypercapnic Respiratory Failure|Obesity Hypoventilation Syndrome|Neuromuscular Disease|Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Surface parasternal electromyography (EMG) set up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of Insulin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Human Insulin Inhalation Powder|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thrombolysis Treated With TNK-tPA in Acute Ischemic Stroke Patients （3T Stroke-II）
Status: UNKNOWN
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Alteplase|DRUG: Tenecteplase|DRUG: Tenecteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PicoWay™ 730 Resolve Fusion for Benign Pigmented Lesions and Wrinkles
Status: COMPLETED
Conditions: Benign Pigmented Lesions|Facial Wrinkles
Interventions: DEVICE: PicoWay™ 532nm fractional handpiece|DEVICE: PicoWay™ 730nm wavelength|DEVICE: PicoWay™ 1064nm fractional handpiece
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Three Different Doses of VAC52416 (ExPEC10V) in Adults Aged 60 to 85 Years in Stable Health
Status: ACTIVE_NOT_RECRUITING
Conditions: Extraintestinal Pathogenic Escherichia Coli Prevention
Interventions: BIOLOGICAL: ExPEC10V|BIOLOGICAL: ExPEC4V|BIOLOGICAL: Prevnar 13|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Carbon Ion Radiation Therapy for Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer|Cancer
Interventions: RADIATION: Carbon Ion|DRUG: Gemcitabine + Cisplatin|DRUG: Gemcitabine + Capecitabine|DRUG: Gemcitabine + Erlotinib|DRUG: Gemcitabine|RADIATION: Photon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endocrown Restoring First Permanent Molar in Children
Status: COMPLETED
Conditions: Comparing Different Types of Restorations for Restoring Endodontically Treated Permanent First Molar in Children
Interventions: OTHER: restoration for endodontically treated molar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Use of MRI in the Assessment of Suspected Scaphoid Fracture With Negative Findings on the Initial Plain Radiography
Status: UNKNOWN
Conditions: Scaphoid Fracture
Interventions: PROCEDURE: Wrist Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Dupilumab 300 mg Every Other Week After Endoscopic Sinus Surgery in Patients With Allergic Fungal Rhinosinusitis (AFRS) on a Background Therapy With Intranasal Corticosteroid Spray
Status: WITHDRAWN
Conditions: Allergic Fungal Rhinosinusitis (AFRS)|Chronic Rhinosinusitis (CRS)|Asthma|Nasal Polyps
Interventions: DRUG: Dupilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Financial Coaching and Lifestyle Intervention for Diabetes Prevention in Low-income Families
Status: RECRUITING
Conditions: Weight Loss
Interventions: BEHAVIORAL: Financial coaching using TrustPlus|BEHAVIORAL: Brighter Bites|BEHAVIORAL: Noom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparative Safety and Bioequivalence of Two Treatments in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: Adapalene and Benzoyl Peroxide Gel|DRUG: Adapalene and Benzoyl Peroxide Gel (Reference)|DRUG: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Study Comparing Naproxen Sodium Extended Release and Naprelan
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Naproxen Sodium, (BAY H6689)|DRUG: Naprelan, (BAY H6689)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Phase II Study to Evaluate Safety of 101-PGC-005 ('005) for Moderate to Severe COVID-19 Disease Along With Standard of Care
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: 101-PGC-005 ('005) + SOC|DRUG: Placebo + SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peer Recovery Support Services for Individuals in Recovery Residences on MOUD
Status: RECRUITING
Conditions: Opioid Use Disorder|Substance Use Disorder
Interventions: BEHAVIORAL: Treatment as Usual (TAU) (Arm 1)|BEHAVIORAL: Peer Recovery Support Services (PRSS) + TAU (experimental- Arm 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stimulus Intensity in Left Ventricular Leads
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: OTHER: LV stimulus intensity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of GSK Biologicals' Pandemic Influenza (H1N1) Candidate Vaccine in Children Aged 10 to Less Than 18 Years
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GSK Biologicals' Influenza investigational vaccine GSK2340274A|BIOLOGICAL: GSK Biologicals' Influenza investigational vaccine GSK2340273A|BIOLOGICAL: Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Early Convalescent Plasma Therapy for High-risk Patients With COVID-19 in Primary Care (the CoV-Early Study)
Status: TERMINATED
Conditions: Covid19
Interventions: BIOLOGICAL: ConvP|BIOLOGICAL: FFP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study, Called DEAR, to Learn More About Treatment With Darolutamide, Enzalutamide and Apalutamide in Men With Non-metastatic Castration-resistant Prostate Cancer in Real World Settings
Status: COMPLETED
Conditions: Non-metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Darolutamide (Nubeqa, BAY1841788)|DRUG: Enzalutamide|DRUG: Apalutamide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Truncal Ultrasound Guided Regional Anesthesia for Implantation and Revision of Automatic Implantable Cardioverter Defibrillators (AICDs) and Pacemakers in Pediatric Patients
Status: UNKNOWN
Conditions: Analgesia After Pacemaker|AICDS Implantation Pediatrics
Interventions: DRUG: LA group|DRUG: B Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Social Determinants of Health to Increase Cancer Screening
Status: RECRUITING
Conditions: Lung Cancer
Interventions: BEHAVIORAL: Social determinants of health screening assessment and referral process|BEHAVIORAL: Current practice - Community-based lunch cancer screening (LungTalk)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Investigation of the Pharmacokinetics of NNC172-2021, at Two Different Dose Levels, in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A|Haemophilia B|Healthy
Interventions: DRUG: NNC172-2021|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antiviral Agent HARVONI® for the Treatment of HCV-associated Indolent B-Cell Lymphoma
Status: UNKNOWN
Conditions: Indolent Lymphoma
Interventions: DRUG: Ledipasvir and sofosbuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of IBI308 and Paclitaxel/Albumin Paclitaxel for SCLC Patients Who Failed Etoposide Chemotherapy
Status: UNKNOWN
Conditions: Extensive-Stage Small Cell Lung Cancer
Interventions: DRUG: Paclitaxel/Albumin-Bound Paclitaxel|DRUG: IBI308
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With COPEGUS (Ribavirin) in Interferon-Naive Patients With Chronic Hepatitis C Infection (CHC).
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: ribavirin [Copegus]|DRUG: ribavirin [Copegus]|DRUG: peginterferon alfa-2a (PEG-IFN alfa-2a) [Pegasys]|DRUG: peginterferon alfa-2a (PEG-IFN alfa-2a) [Pegasys]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Structured Exercise in Patients With Knee Osteoarthritis
Status: RECRUITING
Conditions: Osteoarthritis, Knee|Physical Inactivity
Interventions: DEVICE: Nordic walking or inspiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Positive Airway Pressure (PAP) in Children With Obstructive Sleep Apnea (OSA)
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: PAP therapy|DEVICE: Sham PAP therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Collagen Scaffold Loaded With Umbilical Cord Derived Mesenchymal Stem Cells in Infertile Women With Thin Endometrium or Endometrial Scarring
Status: COMPLETED
Conditions: Infertility, Female|Endometrium
Interventions: PROCEDURE: UC-MSCs therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy of Anti-secretory Versus Oral Immunoglobulins for Reducing the Episodes of Diarrhea in Children
Status: UNKNOWN
Conditions: Diarrhea
Interventions: DRUG: Racecadotril|DRUG: DiaResQ Children's Powder for Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Myocardial Reperfusion After Primary PCI in Patients With High Platelet Reactivity Treated by Cangrelor or Not
Status: COMPLETED
Conditions: ST-elevation Myocardial Infarction
Interventions: DRUG: cangrelor perfusion during PCI|PROCEDURE: standard PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Manual Lymph Drainage During Hospitalization on Swelling, Function and Pain in Patients After Total Knee Replacement
Status: TERMINATED
Conditions: Total Knee Replacement
Interventions: PROCEDURE: Lymphatic massage and individual physiotherapy|PROCEDURE: individual physiotherapy only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Physical Therapy Modalities in Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Low-level laser therapy|OTHER: Ultrasound treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sexual Health and Rehabilitation Online (SHAREonline)
Status: NOT_YET_RECRUITING
Conditions: Cancer Survivorship|Sexual Function Disturbances
Interventions: BEHAVIORAL: Group Session|BEHAVIORAL: Coaching Call|BEHAVIORAL: Educational Materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Clinical Impact of Non-Invasive Hemodynamic Monitoring to Optimize Perioperative Care
Status: TERMINATED
Conditions: Hemodynamic Monitoring
Interventions: DEVICE: invasive Hemodynamic monitoring via Clearsight/Nexfin Systems from Edwards Lifesciences|DEVICE: No Hemodynamic Monitored Guided Assesment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral Vinorelbine in Combination With Trastuzumab for Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Trastuzumab|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Efficacy and Safety Study of Intra-articular CNTX-4975-05 (Capsaicin) vs Placebo in Subjects With OA Knee Pain
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: CNTX-4975-05|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GLPG0259 in Methotrexate-refractory Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: GLPG0259 oral capsule|DRUG: Placebo|DRUG: GLPG0259 (Part B)|DRUG: Placebo (Part B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate E1 Wear, Clinical Performance of E1 Liner in THA in Korean Patient Population
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis|Avascular Necrosis|Traumatic Arthritis|Rheumatoid Arthritis|Legg-perthes Disease
Interventions: DEVICE: E1-Hip Bearing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Tazarotene Cream 0.1% Compared With Adapalene Gel 0.3% in the Treatment of Moderate to Severe Facial Acne Vulgaris
Status: TERMINATED
Conditions: Acne Vulgaris
Interventions: DRUG: Tazarotene Cream 0.1%|DRUG: Adapalene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation With Post-transplant Cyclophosphamide in Patients With Acquired Refractory Aplastic Anemia or in Relapse After Immunosuppression
Status: RECRUITING
Conditions: Refractory Idiopathic Aplastic Anemia|Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation
Interventions: OTHER: Allogenic transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Assessment of the Adjuvant Role of Dietary Supplementation of Antibiotic-tolerant Probiotics in Standard Therapy for the Eradication of Helicobacter Pylori Infection.
Status: RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DIETARY_SUPPLEMENT: IBSA Probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effects of Traditional Chinese Medicine in Topical Use on Upper Extremities Fracture
Status: UNKNOWN
Conditions: Bone Fractures|Traditional Chinese Medicine|Chinese Herbal Medicine
Interventions: OTHER: Ru-Yih-Jin- Huang-Saan(RYJHS), Wan-Yin-Gao-Jia-Jean-Wey(WYGJJW), placebo ( topical agent without therapeutic effects)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An uMbrella Study of BIomarker-driven Targeted Therapy In Patients With Platinum-resistant Recurrent OvariaN Cancer(AMBITION)
Status: UNKNOWN
Conditions: Platinum-resistant Recurrent Ovarian Cancer
Interventions: DRUG: olaparib+cediranib combination therapy|DRUG: durvalumab + olaparib combination therapy|DRUG: durvalumab + chemotherapy treatment|DRUG: durvalumab + tremelimumab + chemotherapy treatment|DRUG: durvalumab + tremelimumab + paclitaxel treatment|DRUG: durvalumab +chemotherapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alpha-lipoic Acid/L-acetyl Carnitine for Progressive Supranuclear Palsy
Status: COMPLETED
Conditions: Progressive Supranuclear Palsy
Interventions: DRUG: alpha-lipoic acid and L-acetyl carnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Glyceryl-Trinitrate Patch and Parecoxib (Valdecoxib) for the Prevention of Pancreatitis After Endoscopic Retrograde Cholangiopancreatography (ERCP)
Status: TERMINATED
Conditions: ERCP|Pancreatitis
Interventions: DRUG: Glyceryl - trinitrate|DRUG: Valdecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Prospective Phase II Efficacy and Safety Study of Anlotinib in Metastatic or Locally Advanced Pheochromocytoma/ Paraganglioma : Open-label Single-arm, Exploratory Trial
Status: UNKNOWN
Conditions: Advanced or Metastatic Paraganglioma/ Pheochromocytoma
Interventions: DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Higher Doses of Remifentanil on Postoperative Pain in Patients Undergoing Thyroidectomy
Status: UNKNOWN
Conditions: Nodular Goiter
Interventions: DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spatiotemporal Stereotactic Body Radiation Therapy for the Treatment of Patients With Polymetastatic Solid Tumors
Status: RECRUITING
Conditions: Metastatic Malignant Solid Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block as Pain Management After Lumbar Fusion Surgery
Status: COMPLETED
Conditions: Spondylolisthesis|Lumbar Disc Herniation|Lumbar Spinal Stenosis|Lumbar Disc Disease|Lumbar Spondylolisthesis|Lumbar Spondylosis|Lumbar Spine Disease|Lumbar Radiculitis|Spinal Fusion|Fusion of Spine|Spondylosis Lumbosacral Region
Interventions: DRUG: Ropivacaine Hydrochloride Injection|DRUG: Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Esthetic, Clinical and Radiographic Outcomes of Immediate and Delayed Implant Placement
Status: RECRUITING
Conditions: Jaw, Edentulous, Partially|Acquired Absence of Single Tooth
Interventions: PROCEDURE: Type 1 implant placement|PROCEDURE: Type 3 implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of XZP-3287 in Combination With Fulvestrant in Patients With Advanced Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Breast Cancer
Interventions: DRUG: XZP-3287+Fulvestrant|DRUG: Placebo + Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psilocybin in Cancer Pain Study
Status: NOT_YET_RECRUITING
Conditions: Opioid-Related Disorders|Pain Management|Pain Management and Care|Advanced Cancer|Advanced Cancers
Interventions: DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utilization of a 3D Printed Customized Knee Extender and At-Home Rehabilitation Program on Patient Outcomes Following ACL Surgery
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Injuries|Anterior Cruciate Ligament Tear|Anterior Cruciate Ligament Rupture
Interventions: DEVICE: 3D printed knee extender device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate Safety and Efficacy of Elamipretide Primary Mitochondrial Myopathy Followed by Open-Label Extension
Status: TERMINATED
Conditions: Primary Mitochondrial Myopathy
Interventions: COMBINATION_PRODUCT: elamipretide|COMBINATION_PRODUCT: placebo comparator|COMBINATION_PRODUCT: elamipretide open label treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrinsic Respiratory Rate Assessment During Mechanical Ventilation to Accelerate Spontaneous Breathing and Extubation
Status: NOT_YET_RECRUITING
Conditions: Reverse Triggering|Patient Ventilator Dyssynchrony
Interventions: OTHER: brief test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Beraprost in Lowering Pulmonary Arterial Pressure in Children
Status: COMPLETED
Conditions: Pediatric Pulmonary Hypertension
Interventions: DRUG: Beraprost Sodium|DRUG: Sildenafil Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Functional Pillow on Neck Pain, Disability, Quality of Sleep and Life
Status: COMPLETED
Conditions: Neck Pain|Posterior Cervical Pain|Sleep Disorders
Interventions: DEVICE: Functional pillow|DEVICE: Placebo general pillow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Chinese Version of the American Shoulder and Elbow Surgeons Standardized Shoulder Assessment Form Questionnaire, Patient Self-report Section: A Cross-cultural Adaptation and Validation Study
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: DIAGNOSTIC_TEST: The Chinese version of the American Shoulder and Elbow Surgeons standardized shoulder assessment form questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Heavy Strength Training in Head and Neck Cancer Survivors
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Neoplasms|Head and Neck Cancer|Head and Neck Squamous Cell Carcinoma|Head and Neck Carcinoma
Interventions: OTHER: Experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Probiotic Bladder Instillation for Prevention of Catheter Associated UTIs in Chronically Catheterized Patients
Status: WITHDRAWN
Conditions: Urinary Tract Infections
Interventions: BIOLOGICAL: Femdophilus probiotic|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Digital Biofeedback System Versus Conventional Home-based Rehabilitation After Total Hip Replacement
Status: COMPLETED
Conditions: Hip Osteoarthritis|Hip Arthrosis
Interventions: DEVICE: Digital biofeedback system|OTHER: Conventional home-based rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Dexmedetomidine on Patient Discomfort in Laparoscopic Cholecystectomy Under Spinal Anesthesia.
Status: UNKNOWN
Conditions: Shoulder Pain
Interventions: DRUG: Dexmedetomidine|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alemtuzumab With or Without Methotrexate and Mercaptopurine in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Recurrent Childhood Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: alemtuzumab|DRUG: methotrexate|DRUG: mercaptopurine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Demineralized Whole-tooth vs Demineralized Particulate Dentin Grafts in Alveolar Ridge Preservation
Status: UNKNOWN
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: Alveolar ridge preservation using whole-tooth dentin graft|PROCEDURE: Alveolar ridge preservation using particulate dentin graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of HGP1910 and HCP1903 in Patients With Primary Hypercholesterolemia
Status: COMPLETED
Conditions: Primary Hypercholesterolemia
Interventions: DRUG: HGP1910|DRUG: HCP1903|DRUG: HGP1909|DRUG: HGP1911
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Response Patterns to the Electrical Stimulation of Epidural Catheters With Varying Pulse Widths in Term Pregnant Women
Status: TERMINATED
Conditions: Labor Pain
Interventions: DEVICE: Nerve stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Stage III Ovarian Epithelial Cancer or Gastrointestinal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Gastric Cancer|Gastrointestinal Carcinoid Tumor|Gastrointestinal Stromal Tumor|Ovarian Cancer|Peritoneal Cavity Cancer|Small Intestine Cancer
Interventions: DRUG: carboplatin|DRUG: cisplatin|DRUG: floxuridine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Prescription for Health Equity: A Healthcare Provider-based Produce Prescription Program for People With Prediabetes and Type 2 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Pre Diabetes|Diabetes Mellitus, Type 2
Interventions: OTHER: Produce Prescription Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase I, Multicenter, Open-Label, Multi-Part, Dose-escalation Study of RAD1901 in Postmenopausal Women With Advanced Estrogen Receptor Positive and HER2-Negative Breast Cancer
Status: COMPLETED
Conditions: Advanced ER+, HER2-Negative Breast Cancer
Interventions: DRUG: Elacestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Marijuana Approach Bias Retraining and Neural Response in Youth
Status: COMPLETED
Conditions: Alcohol Approach/Avoidance Task|Sham Approach/Avoidance Task
Interventions: BEHAVIORAL: Marijuana Approach Avoidance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of KER-050 to Treat Anemia Due to Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes
Status: RECRUITING
Conditions: Myelodysplastic Syndromes|Cytopenia
Interventions: DRUG: KER-050
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Cytotoxic and Genotoxic Effect of Toothpastes With Different Forms of Fluoride on the Buccal Mucosa
Status: RECRUITING
Conditions: DNA Damage
Interventions: OTHER: Toothpaste without fluoride|OTHER: Toothpaste with sodium fluoride|OTHER: Toothpaste with sodium monofluorophosphate|OTHER: Toothpaste with amine fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Acute Uncomplicated Seasonal Influenza A in Adult Subjects
Status: COMPLETED
Conditions: Influenza A
Interventions: DRUG: VX-787 300 mg|DRUG: VX-787 600 mg|DRUG: Oseltamivir 75 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Drug Interaction Study of Valproic Acid and Paliperidone Extended-Release (ER) in Patients With Schizophrenia, Bipolar I Disorder, or Schizoaffective Disorder
Status: COMPLETED
Conditions: Schizophrenia|Bipolar Disorder|Psychotic Disorders
Interventions: DRUG: divalproex sodium ER/paliperidone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Use Quantitative Microradiography to Predict the Periprosthetic Bone Loss in Distal Femur After Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Periprosthetic Bone Loss in Total Knee Replacement
Interventions: RADIATION: dual energy x-ray absorptiometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 5 Years of Adjuvant Imatinib in Patients With Gastrointestinal Stromal Tumor With a High Risk
Status: RECRUITING
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Imatinib Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of 1,550 and 755 Laser in a Split-face Trial
Status: COMPLETED
Conditions: Acne Scars - Mixed Atrophic and Hypertrophic
Interventions: DEVICE: 1,550 fracionated photothermolysis laser|DEVICE: 755 picosecond laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Of 2 Doses Of Temsirolimus (Torisel) In Patients With Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: temsirolimus|DRUG: temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcome and Future Liver Remnant Regenerative Response in Laparoscopic Versus Open ALPPS
Status: RECRUITING
Conditions: Liver Cancer
Interventions: PROCEDURE: Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of LASIK Versus PRK in Asians With Mild and Moderate Myopia
Status: COMPLETED
Conditions: Myopia
Interventions: PROCEDURE: Laser in Situ Keratomileusis (LASIK)|PROCEDURE: Photorefractive Keratectomy (PRK)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Surgery Without Neoadjuvant Chemoradiotherapy Compared With Neoadjuvant Chemoradiotherapy for Rectal Cancer With Negative Circumferential Resection Margin Based on MRI Assessment, a Perspective Multicenter Randomized Controlled Trial
Status: UNKNOWN
Conditions: Circumferential Resection Margin|Intraoperative Perforation of Rectum|Local Recurrence of Malignant Tumor of Rectum|Disease-free Survival|Overal Survival
Interventions: OTHER: neoadjuvant chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Catheter Ablation vs. Medical Therapy in Congested Hearts With AF
Status: TERMINATED
Conditions: Congestive Heart Failure|Left Ventricular Failure|Atrial Fibrillation
Interventions: DEVICE: Catheter Ablation|DRUG: FDA approved anti arrhythmic drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Twenty-Four-Month Clinical Comparison of Two Bulk-Fill and Microhybrid Composite Restorations
Status: COMPLETED
Conditions: Dental Restoration Failure of Marginal Integrity
Interventions: OTHER: Bulk-Fill and Microhybrid Composite Resins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Catheter-related Infections Using Antibiotic-coated Versus Conventional Catheters in Children
Status: TERMINATED
Conditions: Infection Prevention
Interventions: DEVICE: Antibiotic-impregnated Catheters (M/R)|DEVICE: Non-impregnated Catheters (C/S)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Aumolertinib Combined With Anlotinib as 1st Line Treatment in Advanced Lung Cancer EGFR Mutation With TP53 Co-Mutation
Status: NOT_YET_RECRUITING
Conditions: Aumolertinib|Anlotinib|TP53|NSCLC|EGFR Activating Mutation
Interventions: DRUG: Aumolertinib,Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Creatine Supplementation on Muscle Mass and Function Among Older Women Subjected to Resistance Training
Status: COMPLETED
Conditions: Muscle Weakness
Interventions: OTHER: Resistance exercise training|DRUG: Creatine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Tonsillar Pillar Closure on Postoperative Pain and Bleeding Risk After Tonsillectomy
Status: COMPLETED
Conditions: Hemorrhage|Pain
Interventions: PROCEDURE: suture one tonsillar fossa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT