pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluate Breast Masses Using a New Method of Ultrasound Contrast to Detect Abnormal Blood Flow in Breasts
Status: WITHDRAWN
Conditions: Breast Cancer|Breast Abnormalities
Interventions: PROCEDURE: Ultrasound Imaging with Contrast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ACOART SCB BIF: Treatment of Coronary Bifurcation Lesion by Sirolimus Coated Balloon vs Paclitaxel Coated Balloon
Status: RECRUITING
Conditions: Coronary Bifurcation Lesions
Interventions: DEVICE: Sirolimus Coated Balloon Catheter|DEVICE: a Paclitaxel Coated Balloon Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic Predictors of Analgesic Efficacy of Propranolol for Treating Postoperative Pain
Status: TERMINATED
Conditions: Postoperative Pain
Interventions: DRUG: Propranolol PO|DRUG: IV-PCA morphine|DRUG: Placebo PO|PROCEDURE: Quantitative Sensory Testing (QST)|OTHER: Psychometric assessment|GENETIC: COMT-haplotypes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Observation of Use of Claritin (Loratadine) Tablet, RediTabs, and Dry Syrup in Children (Study P05834)(COMPLETED)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal|Rhinitis, Allergic, Perennial|Urticaria|Pruritus
Interventions: DRUG: loratadine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 68Ga-FAP-RGD PET/CT : Dosimetry and Preliminary Clinical Translational Studies
Status: RECRUITING
Conditions: Tumor
Interventions: DRUG: 68Ga-FAP-RGD|DRUG: 68Ga-FAP-RGD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pharmacokinetic Study of Nutri-PEITC Jelly in Head and Neck Cancer Survivors
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DIETARY_SUPPLEMENT: Nutri-PEITC jelly
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Drug Interactions Between Lopinavir/Ritonavir and Oral or Patch Contraceptives in HIV Infected Women
Status: COMPLETED
Conditions: HIV Infections|Pregnancy
Interventions: DRUG: Lopinavir/ritonavir|DRUG: Ortho Novum 1/35|DRUG: Ortho Evra
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multicenter Study Assessing the Efficacy and Safety of DE-126 Ophthalmic Solution 0.002% Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: DE-126 Ophthalmic Solution 0.002% QD|DRUG: Timolol Maleate Ophthalmic Solution 0.5% BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Albumin-bound Paclitaxel Plus Camrelizumab for Advanced Soft Tissue Sarcoma.
Status: RECRUITING
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Albumin-Bound Paclitaxel|DRUG: Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Biomarker Study of RL-007 in Subjects With Schizophrenia
Status: COMPLETED
Conditions: Cognitive Impairment|Schizophrenia
Interventions: DRUG: RL-007|DRUG: RL-007 Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Efficacy and Safety of SAR566658 Treatment in Patients With CA6 Positive Metastatic Triple Negative Breast Cancer
Status: TERMINATED
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: SAR566658 (ACT14884)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega Tots: A Randomized, Controlled Trial of Long-chain Polyunsaturated Fatty Acid Supplementation of Toddler Diets and Developmental Outcomes
Status: COMPLETED
Conditions: Preterm Birth|Child Development
Interventions: DRUG: Docosahexaenoic Acid + Arachidonic Acid (DHA+AA)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Evaluate the Oral Absorption of Nepadutant in Infants
Status: COMPLETED
Conditions: Infantile Colic|Infantile Functional Gastrointestinal Disorders
Interventions: DRUG: Nepadutant|DRUG: Nepadutant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Croup Dosing Study
Status: NOT_YET_RECRUITING
Conditions: Croup
Interventions: DRUG: 0.15 mg/kg dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety, Pharmacokinetics, and Pharmacodynamics of Multiple Doses of E2609 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: E2609|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Study Of Tanezumab In Osteoarthritis
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: BIOLOGICAL: tanezumab|BIOLOGICAL: tanezumab|BIOLOGICAL: tanezumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oblimersen, Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Treating Patients With Stage II, Stage III, or Stage IV Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: oblimersen sodium|BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: prednisone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Treatment of Postoperative Hypoparathyroidism Using Cultured Allogenic Parathyroid Cells
Status: UNKNOWN
Conditions: Postoperative Hypoparathyroidism
Interventions: BIOLOGICAL: Allogenic parathyroid cells|OTHER: Standard treatment according to the Clinical protocols
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Cabozantinib and Nivolumab in Refractory Metastatic Microsatellite Stable (MSS) Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Adenocarcinoma|Colon Cancer|Colon Adenocarcinoma|Rectum Cancer|Rectal Cancer|Rectal Adenocarcinoma|Colorectal Cancer
Interventions: DRUG: Cabozantinib|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of a Closed-incision Negative-pressure Therapy (Prevena®) on Bilateral Groin Incision
Status: UNKNOWN
Conditions: Bilateral Vascular Groin Surgery
Interventions: DEVICE: Closed-incision Negative-pressure Therapy - Dry dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GON-block in Chronic Migraine: a Randomized, Double- Blind, Placebo-controlled Study
Status: UNKNOWN
Conditions: Chronic Migraine
Interventions: DRUG: Betamethasone and local anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of Tolcapone for Cognition in Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: OTHER: Placebo|DRUG: Tolcapone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Immersive Virtual Reality Based Exersice in Post-mastectomy Lymphedema Patients
Status: NOT_YET_RECRUITING
Conditions: Lymphedema Arm
Interventions: PROCEDURE: immersive virtual reality|PROCEDURE: traditional physicaltherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Lactisole on the Responses to Glucose Solution
Status: UNKNOWN
Conditions: Blood Glucose|Appetite|Therapeutic Uses|Hormones
Interventions: OTHER: Lactisole|DIETARY_SUPPLEMENT: Lactisole|DIETARY_SUPPLEMENT: Lactisole|DIETARY_SUPPLEMENT: Lactisole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Graft Failure After Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Primary Graft Failure|Secondary Graft Failure
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|RADIATION: Total Body Irradiation|BIOLOGICAL: Hematopoietic stem cell infusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study for Upper Limb Motor Restoration in Chronic Stroke Patients Using Personalized Neuro-technologies
Status: COMPLETED
Conditions: Stroke, Cerebral
Interventions: DEVICE: Paretic upper limb functional electric stimulation through RehaStim|DEVICE: Non-invasive transcranial current stimulation through DC-Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Corticosteroid and Repeated Dextrose Hydro-dissection for Carpal Tunnel Syndrome Patients
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: Triamcinolone Acetonide|DRUG: Dextrose 5% in water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, and PK of Pacritinib
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: oral dose of 200 mg pacritinib twice daily (BID)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Apixaban for the Prevention of Thrombosis-related Events Following Knee Replacement Surgery
Status: COMPLETED
Conditions: Deep Vein Thrombosis|Pulmonary Embolism
Interventions: DRUG: Enoxaparin + Placebo|DRUG: Apixaban + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Safety and Efficacy of Adalimumab When Added to Inadequate Standard Anti-Rheumatic Therapy in Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 48-Week Study Of GW433908 And Ritonavir Or GW433908 Alone, Twice Daily In Pediatric Patients With HIV Infection
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus I
Interventions: DRUG: LEXIVA (GW433908)|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ixazomib (MLN9708) and Dexamethasone in High Risk Smoldering Multiple Myeloma: A Clinical and Correlative Pilot Study
Status: COMPLETED
Conditions: Multiple Myeloma|High Risk Smoldering Multiple Myeloma
Interventions: DRUG: Ixazomib (MLN9708)|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Post-Traumatic Stress Disorder (PTSD) in Sexually Abused Children
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Trauma-Focused CBT|BEHAVIORAL: Child-Centered Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Office Based Transperineal Laser Ablation for Benign Prostatic Hyperplasia HYPERPLASIA
Status: ACTIVE_NOT_RECRUITING
Conditions: Male Urogenital Diseases|Genital Diseases, Male|Prostatic Disease|Prostatic Hyperplasia
Interventions: DEVICE: SoracteLite(TM) TPLA for BPH
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of RNS60 Given by IV to Healthy Subjects
Status: COMPLETED
Conditions: Myocardial Infarct
Interventions: DRUG: RNS60|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Community Access, Retention in Care, and Engagement for Hepatitis C Treatment
Status: COMPLETED
Conditions: Hepatitis C
Interventions: BEHAVIORAL: PREP-C|BEHAVIORAL: Modified ECHO|BEHAVIORAL: Patient Telemedicine Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase I Multicenter, Randomized, Double-Blind Trial to Evaluate the Safety and Immunogenicity of Recombinant Vaccinia Virus Expressing the Envelope Glycoproteins of Human Immunodeficiency Virus
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: HIVAC-1e|BIOLOGICAL: gp160 Vaccine (MicroGeneSys)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Facilitated Tucking and White Noise on Stress and Sleep of Newborns in Nasal CPAP
Status: COMPLETED
Conditions: Newborn|Newborn Sleep|Newborn Stress
Interventions: OTHER: white noise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Molecular vs Conventional Microbiologic Diagnosis for Infections in Lung Transplantation
Status: RECRUITING
Conditions: Lung Transplant Infection|Molecular Diagnostic|Bacterial Infections|Pneumonia|Tracheobronchitis
Interventions: DIAGNOSTIC_TEST: BioFire Pneumonia Panel Plus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Reproducibility of a Fatigability Test Fitted to Patients With Spinal Muscular Atrophy
Status: NOT_YET_RECRUITING
Conditions: Spinal Amyotrophy|Infantile Spinal Muscular Atrophy|Juvenile Spinal Muscular Atrophy
Interventions: OTHER: Thumb test|OTHER: Grip test|OTHER: Quadriceps Intermittent Fatigue test (QIF test))
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors
Status: WITHDRAWN
Conditions: Brain Stem Neoplasms|Glioma|Pinealoma
Interventions: DRUG: IMC-A12|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aequalis Pyrocarbon IDE; Replacing the Humeral Head in Hemi-Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis|Avascular Necrosis|Traumatic Arthritis
Interventions: DEVICE: Aequalis Pyrocarbon Humeral Head
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Trastuzumab, Capecitabine y Oxaliplatine as Treatment Gastric Cancer Metastatic (HER2)Positive
Status: COMPLETED
Conditions: Stage IV Gastric Cancer With Metastasis
Interventions: DRUG: Trastuzumab|DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Segmentectomy Versus Lobectomy for Lung Adenocarcinoma ≤ 2cm
Status: RECRUITING
Conditions: Lung Adenocarcinoma
Interventions: PROCEDURE: Segmentectomy with systemic lymph node dissection|PROCEDURE: Lobectomy with hilar and mediastinal lymph node dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Palatability and Acceptability of Different Brensocatib Oral Liquid Formulations in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Brensocatib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-VEGF Instead of Intraoperative Fan-shaped Photocoagulation in BRVO Combined With Vitreous Hemorrhage
Status: UNKNOWN
Conditions: Anti-VEGF|Branch Retinal Vein Occlusion|Vitrectomy
Interventions: PROCEDURE: anti-VEGF|PROCEDURE: fan-shaped photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of IVX-A12 in Participants of 60 to 85 Years of Age
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: BIOLOGICAL: IVX-A12|BIOLOGICAL: IVX-A12|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Rescue Antenatal Steroids and Pulmonary Function Tests in Preterm Infants
Status: COMPLETED
Conditions: Respiratory Compliance|Functional Residual Capacity|Pulmonary Function Testing
Interventions: DRUG: betamethasone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: [68Ga]Ga-HBED-CC-exendin-4 and [68Ga]Ga-NOTA-exendin-4 PET/CT Imaging in the Same Group of Insulinoma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Insulinoma
Interventions: DRUG: [68Ga]Ga-HBED-CC-exendin-4|DRUG: [68Ga]Ga-NOTA-exendin-4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Early Versus Standard Central Line Removal on Growth of Very Low Birth Weight Premature Infants
Status: UNKNOWN
Conditions: Growth Failure|CLABSI - Central Line Associated Bloodstream Infection
Interventions: PROCEDURE: Central line removal at 100ml/kg/day.|PROCEDURE: Central line removal at 140ml/kg/day.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Curcumin on Liver Fat Content in Obese Subjects
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease|Insulin Resistance|Glucose Tolerance Impaired|Obesity, Abdominal
Interventions: DIETARY_SUPPLEMENT: Curcumin (Meriva®)|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Evidence-Based Primary Care for Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease|Chronic Kidney Insufficiency|Chronic Renal Diseases|Chronic Renal Insufficiency|Kidney Insufficiency, Chronic
Interventions: OTHER: Facilitated Clinical Decision Support|OTHER: Clinical Decision Support Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Titration Pressures in Sleep Apnea Patients Using ThermoSmart® Versus Conventional Humidification
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: Heated breathing tube (CPAP with ThermoSmart)|DEVICE: Non heated breathing tube (CPAP with conventional humidification)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of L19TNF in Previously Treated Patients With Advanced Stage or Metastatic Soft-tissue Sarcoma
Status: RECRUITING
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Dacarbazine|DRUG: onfekafusp alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Efficacy of RGT-61159 in Adults With Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC)
Status: RECRUITING
Conditions: Adenoid Cystic Carcinoma|Colorectal Cancer
Interventions: DRUG: RGT-61159
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Reversal of the Anticoagulant Effects of Milvexian by 4-Factor Prothrombin Complex Concentrate (4F-PCC) (Part 1) and Recombinant Human Factor VIIa (rFVIIa) (Part 2) in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Milvexian|BIOLOGICAL: 4-Factor Prothrombin Complex Concentrate (4F-PCC)|BIOLOGICAL: Recombinant Human Factor VIIa (rFVIIa)|BIOLOGICAL: Placebo matching to 4F-PCC|BIOLOGICAL: Placebo matching to rFVIIa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ivermectin/ Permethrin for Scabies
Status: COMPLETED
Conditions: Scabies
Interventions: DRUG: Ivermectin Tablets|DRUG: Permethrin Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of Rehabilitation Using the "Wii" on Upper Limb Kinematics in Chronic Stroke Patients.
Status: COMPLETED
Conditions: Post-stroke Hemiparetic Patients (at Least 6 Months Post Stroke)|Age Between 18-75 Years
Interventions: BEHAVIORAL: WII Rehabilitation|BEHAVIORAL: Traditional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Changes in Triglyceride and Other Lipids (Levels of Fats Found in Blood) When Taking Darunavir Compared to Atazanavir in HIV-infected Patients That Have Never Received Treatment
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: ritonavir|DRUG: ritonavir|DRUG: darunavir|DRUG: emtricitabine [FTC]/tenofovir [TDF]|DRUG: emtricitabine [FTC]/tenofovir [TDF]|DRUG: atazanavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Regulatory Function of Inhaled Asthma Medication Salbutamol on Thermogenesis
Status: NOT_YET_RECRUITING
Conditions: Effect of Asthma Medication Salbutamol on Obesity
Interventions: DRUG: Salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Tear Supplements on Contact Lens Comfort
Status: COMPLETED
Conditions: Dry Eye Syndromes|Meibomian Gland Dysfunction
Interventions: OTHER: Systane Balance eye drops|OTHER: Systane Contacts eye drops|OTHER: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cryospray to Reduce Pain During Venous Cannulation
Status: COMPLETED
Conditions: Catheterization|Anesthetics, Intravenous|Elective Surgical Procedures
Interventions: PROCEDURE: Saline spray|PROCEDURE: Cryospray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Anlotinib as Maintenance Treatment After First-line Chemotherapy in SCLC
Status: UNKNOWN
Conditions: Carcinoma|Lung Neoplasm|Small Cell Lung Cancer
Interventions: DRUG: Anlotinib Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Incorporation of Vitamin C Into Platelet Rich Fibrin Scaffold in Treatment of Intra-osseous Periodontal Defects
Status: UNKNOWN
Conditions: Periodontal Bone Loss
Interventions: COMBINATION_PRODUCT: combination of vitamin C and platelet rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: iACT With Pain: an ICT-delivered Intervention for Self-management of Chronic Pain
Status: UNKNOWN
Conditions: Chronic Pain
Interventions: BEHAVIORAL: iACTwithPain (ACT+compassion)|BEHAVIORAL: ACT-only intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Modified Stepping Trainings in Frailty Elderly With Physical Performance- a Prospective Randomized Controlled Trial
Status: COMPLETED
Conditions: Rehabilitation|Training|Respiratory Muscle Strength
Interventions: OTHER: modified stepping trainings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chronic Cannabis Smoking, Oxidative Stress and the Pulmonary Innate Immune Response
Status: RECRUITING
Conditions: Cannabis Smoking|Oxidative Stress
Interventions: PROCEDURE: Bronchoscopy|RADIATION: Chest X-ray|PROCEDURE: Venipuncture|PROCEDURE: Intravenous Catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Everolimus Plus Best Supportive Care vs Placebo Plus Best Supportive Care in the Treatment of Patients With Advanced Neuroendocrine Tumors (GI or Lung Origin)
Status: COMPLETED
Conditions: Advanced NET of GI Origin|Advanced NET of Lung Origin|Neuroendocrine Tumors
Interventions: DRUG: Everolimus|DRUG: Placebo|OTHER: Best suportive care (BSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strides for Life I: Increasing Physical Activity in Stage 1 Lung Cancer Patients
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BEHAVIORAL: Physical activity plus positive affect|BEHAVIORAL: Physical activity plus education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Biomarker-driven Therapeutic Strategy for Esophageal Cancer Chemoradiotherapy in Patients With Resectable Adenocarcinoma of the ESophagus and Esophagogastric Junction
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: OTHER: BIRC3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Diaphragm-releasing Techniques on the Lumbar Spine and Diaphragmatic Function in Healthy Women
Status: COMPLETED
Conditions: Healthy Individuals
Interventions: PROCEDURE: Diaphragm lift|PROCEDURE: Relaxation of the diaphragm pillars
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of MIK665, a Mcl-1 Inhibitor, in Patients With Refractory or Relapsed Lymphoma or Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma (MM), Lymphoma, Large B-Cell, Diffuse (DLBCL), Lymphoma
Interventions: DRUG: MIK665
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cervical Stability Training on Somatosensory Evoked Potential and Cervical Spine in Forward Head Posture
Status: UNKNOWN
Conditions: Forward Head Posture
Interventions: OTHER: cervical stability training|OTHER: traditional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Of Chocolate Balloon Dilatation Versus Plain Balloon Dilatation to Treat Arteriosclerosis Occlusive Disease of Lower Extremity
Status: RECRUITING
Conditions: Atherosclerosis|Ischemia
Interventions: DEVICE: chocolate balloon|DEVICE: plain balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Botulinum Toxin Type A for Injection(HengLi®) in Subjects With Post-stroke Upper Limb Spasticity
Status: COMPLETED
Conditions: Cerebrovascular Accident
Interventions: DRUG: Botulinum Toxin Type A for Injection|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SBRT and Oncolytic Virus Therapy Before Pembrolizumab for Metastatic TNBC and NSCLC
Status: COMPLETED
Conditions: Metastatic Non-small Cell Lung Cancer|Metastatic Triple-negative Breast Cancer
Interventions: BIOLOGICAL: ADV/HSV-tk|DRUG: Valacyclovir|RADIATION: SBRT|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Prosthetic Feet for the Geriatric Patients(CPF)
Status: UNKNOWN
Conditions: Amputation
Interventions: DEVICE: SACH prosthetic foot, 1M10 prosthetic foot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Erlotinib With or Without Investigational Drug (U3-1287) in Subjects With Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: NSCLC (Advanced Non-small Cell Lung Cancer)
Interventions: DRUG: U3-1287|DRUG: Erlotinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Safety and Efficacy Study of Abiraterone Acetate in Participants With Advanced Prostate Cancer Who Failed Androgen Deprivation and Docetaxel-Based Chemotherapy
Status: COMPLETED
Conditions: Prostate Neoplasms
Interventions: DRUG: Abiraterone acetate|DRUG: Glucocorticoid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Anemia|Fatigue|Fever|Lymphadenopathy|Lymphocytosis|Night Sweats|Recurrent Chronic Lymphocytic Leukemia|Recurrent Plasma Cell Myeloma|Refractory Chronic Lymphocytic Leukemia|Refractory Plasma Cell Myeloma|Splenomegaly|Thrombocytopenia|Weight Loss
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Metformin Hydrochloride|OTHER: Pharmacological Study|DRUG: Ritonavir|OTHER: Quality-of-Life|OTHER: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Moderate to Severe Glabellar Lines
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: BIOLOGICAL: botulinum toxin|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interferon-alpha2a Versus Cyclosporin A for Severe Ocular Behcet's Disease (INCYTOB)
Status: COMPLETED
Conditions: Behcet's Disease|Panuveitis|Posterior Uveitis|Retinal Vasculitis
Interventions: DRUG: Cyclosporin A|DRUG: Interferon-alpha2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Injection of Autologous Bone Marrow Aspirate in Patients With Degenerative Disc Disease.
Status: UNKNOWN
Conditions: Lumbar Disc Disease
Interventions: PROCEDURE: Autologous bone marrow aspirate injected intradiscal after microdiscectomy|PROCEDURE: Discectomy only
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Screening for Cancer in Patients With Unprovoked VTE
Status: UNKNOWN
Conditions: Venous Thromboembolic Disease|Respiratory Disease|Pulmonary Disease|Deep Venous Thrombosis|Pulmonary Embolism|Screening|Undefined
Interventions: DRUG: Fludeoxyglucose 18F
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy of Double Doses of Oral Esomeprazole in Preventing Rebleeding for Patients With Bleeding Peptic Ulcers
Status: COMPLETED
Conditions: Peptic Ulcer Bleeding
Interventions: DRUG: esomeprazole (Nexium®, AstraZeneca AB, Södertälje, Sweden)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Evaluation of IBI308 in Treatment of Patients With Relapsed/Refractory Classical Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Relapsed/Refractory Classical Hodgkin's Lymphoma
Interventions: DRUG: PD1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Pharmacokinetics, Pharmacodynamics, and Safety of Sargramostim Administered Subcutaneously, Intravenously, or by Inhalation
Status: COMPLETED
Conditions: Drug Kinetics|Drug Effects on Physiology
Interventions: BIOLOGICAL: sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Viral Kinetic Study With Viramidine in Therapy-Naive Patients With Chronic Hepatitis C
Status: TERMINATED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Viramidine|DRUG: Peginterferon alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess a Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Allografts
Status: WITHDRAWN
Conditions: Haematological Malignancy|Acute Leukemia|Myelodysplastic Syndromes|Hemoglobinopathy in Children|Bone Marrow Aplasia|Severe Combined Immunodeficiency
Interventions: OTHER: Physical activity program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Thermal Pulsation System (Lipiflow) Treatment for Ocular Surface Disease Due to Meibomian Gland Dysfunction
Status: COMPLETED
Conditions: Evaporative Dry Eye Disease
Interventions: DEVICE: Lipiflow® application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ascending Dose Study of OPC-108459 Intravenous Infusions in Patients With Paroxysmal and Persistent Atrial Fibrillation
Status: TERMINATED
Conditions: Atrial Fibrillation|Paroxysmal Atrial Fibrillation|Persistent Atrial Fibrillation
Interventions: DRUG: OPC-108459|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I, Healthy Subject, Safety, Tolerability and Pharmacokinetic Study of an M1 Agonist to Treat Cognitive Impairment
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: HTL0009936|DRUG: HTL0009936 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prebiotic Agave Derivated Metlin & Metlos in Infant Formula
Status: COMPLETED
Conditions: Healthy Term Babies
Interventions: DIETARY_SUPPLEMENT: Infant Formula|DIETARY_SUPPLEMENT: Exclusively breast milk|DIETARY_SUPPLEMENT: Metlin+metlos+Lactobacillus GG|DIETARY_SUPPLEMENT: Metlin + Lactobacillus GG|DIETARY_SUPPLEMENT: Metlos + lactobacillus GG|DIETARY_SUPPLEMENT: Lactobacillus GG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Endomysial Fibrosis, Muscular Inflammatory Response and Calcium Homeostasis Dysfunction in Duchenne Muscular Dystrophy
Status: UNKNOWN
Conditions: Duchenne Muscular Distrophy (DMD)
Interventions: OTHER: Muscle biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 3 Trial of E7777 in Combination With CHOP Compared With CHOP Alone for the First-Line Treatment of Peripheral T-cell Lymphoma
Status: WITHDRAWN
Conditions: Peripheral T-Cell Lymphoma
Interventions: DRUG: E7777
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ketamine in the Prevention of Hypoventilation in Patients Undergoing Deep Sedation Using Propofol and Fentanyl
Status: WITHDRAWN
Conditions: Hypercarbia
Interventions: DRUG: Ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study to Explore the Role of Gut Flora in Acne
Status: UNKNOWN
Conditions: Acne|Acne Vulgaris|Acne Keloidalis|Acne Keloid|Acne Conglobata|Acne Rosacea|Acne Inversa|Acne Cystic|Acne Pomade|Acne Indurata|Acne Papular|Acne Tropica|Acne Urticata|Acne Fulminans|Acne Follicular|Acne Tropicalis|Acne Detergicans|Acne Iodide|Acne Varioliformis
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intratumoral TriMix Injections in Early Breast Cancer Patients
Status: RECRUITING
Conditions: Breast Cancer Female|Early-stage Breast Cancer
Interventions: DRUG: Trimix|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: First-in-human Evaluation of [18F]CETO
Status: COMPLETED
Conditions: Primary Aldosteronism Due to Aldosterone Producing Adenoma|Primary Aldosteronism Due to Nodular Hyperplasia|Adrenal Cushing Syndrome|Non-Secretory Adrenal Adenoma|Adrenocortical Carcinoma
Interventions: DRUG: F18CETO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects with Narcolepsy Type 2
Status: RECRUITING
Conditions: Narcolepsy Type 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy of ONS to Reduce Postoperative Complications Associated With Pancreatic Surgery
Status: TERMINATED
Conditions: Pancreatic Cancer|Chronic Pancreatitis
Interventions: DIETARY_SUPPLEMENT: Ensure Surgical|OTHER: Nutrition counseling|OTHER: Low-intensity exercise therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REscue Stenting With CREDO® Heal for Recanalisation After Unsuccessful Thrombectomy (RECHRUT)
Status: RECRUITING
Conditions: Rescue Stenting
Interventions: DEVICE: Rescue stenting with CREDO heal Stent together with NeuroSpeed PTA Balloon Catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vaccine Therapy in Treating Patients With Stage IV Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: D1/3-MAGE-3-His fusion protein|BIOLOGICAL: SB-AS02B adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resonant Frequency rTMS: A Novel Approach to Target Circuit Modulation in Major Depressive Disorder
Status: ENROLLING_BY_INVITATION
Conditions: MDD|Depression
Interventions: DEVICE: Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antineoplaston Therapy in Treating Patients With Meningioma
Status: TERMINATED
Conditions: Meningioma
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Peripheral Nerve Stimulation for Restless Legs Syndrome
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DEVICE: Noctrix Health NPNS device v1.0 - Active|DEVICE: Noctrix Health NPNS device v1.0 - Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Phase II Study of Intensity Modulated Radiation Therapy (IMRT) in High Risk Abdominal Neuroblastoma
Status: TERMINATED
Conditions: Abdominal Neuroblastoma
Interventions: RADIATION: Intensity Modulated Radiation Therapy (IMRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Dysfunction in Patients With Hematological Diseases Referred to Stem Cell Transplant
Status: RECRUITING
Conditions: Hematologic Diseases|Chronic Myeloid Leukemia|Acute Myeloid Leukemia|Acute Lymphoid Leukemia|Myelodysplastic Syndromes|Non Hodgkin Lymphoma|Stem Cell Transplant Complications|Chronic Lymphocytic Leukemia
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Agile Development of Innovative, Interactive Hazard Recognition and Mitigation Tools/Learning E-platforms for Workers Involved in Disaster Rescue and Recovery
Status: NOT_YET_RECRUITING
Conditions: Work-related Illness
Interventions: BEHAVIORAL: Pocket Ark
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intranasal Dexmedetomidine vs Midazolam-ketamine Combination for Premedication of Pediatric Patients
Status: COMPLETED
Conditions: Premedication|Oculocardiac Reflex
Interventions: DRUG: Dexmedetomidine|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Remote Ischemic Conditioning, Bimanual Skill Learning, and Corticospinal Excitability
Status: RECRUITING
Conditions: Unilateral Cerebral Palsy|Hemiplegic Cerebral Palsy|Remote Ischemic Conditioning
Interventions: BEHAVIORAL: Remote Ischemic Conditioning (RIC)|BEHAVIORAL: Sham conditioning|BEHAVIORAL: Hand Arm Bimanual Intensive Therapy (HABIT)|BEHAVIORAL: Bimanual Cup Stacking Training|BEHAVIORAL: Balance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Pioglitazone and SES With type2 DM
Status: COMPLETED
Conditions: Coronary Artery Disease|Type 2 Diabetes Mellitus
Interventions: DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of Ezetimibe on Glucose Metabolism in Type 2 Diabetics With Hypercholesterolemia (P06541)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Ezetimibe|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PMCF-study Using Novosyn® Quick Suture Material in Ophthalmic Surgery
Status: WITHDRAWN
Conditions: Dacryocystorhinostomy|Ectropion|Entropion|Ptosis|Eyelid Tumor Resection|Blepharoplasty
Interventions: DEVICE: Novosyn® Quick|DEVICE: Vicryl® Rapid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Triamcinolone and Moxifloxacin Injection After Cataract Surgery
Status: COMPLETED
Conditions: Pharmacological Action
Interventions: DRUG: intra-vitreal triamcinolone-moxifloxacin injection after cataract surgery as a prophylactic measures against post-operative endophthalmitis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Effectiveness and Safety of ULTRACET® (Tramadol Hydrochloride/Acetaminophen) Versus ULTRAM® (Tramadol Hydrochloride) Versus Placebo in Patients With Pain After Oral Surgery
Status: COMPLETED
Conditions: Surgery, Oral|Pain, Postoperative
Interventions: DRUG: tramadol hydrochloride + acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Tremelimumab and Durvalumab in Combination or Alone in Treating Patients With Recurrent Malignant Glioma
Status: COMPLETED
Conditions: Malignant Glioma|Recurrent Glioblastoma
Interventions: BIOLOGICAL: Durvalumab|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Surgical Procedure|BIOLOGICAL: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT