pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of the Safety of Brolucizumab 6 mg in Prefilled Syringe in Patients With Neovascular Age Related Macular Degeneration
Status: COMPLETED
Conditions: Neovascular Age Related Macular Degeneration
Interventions: DRUG: RTH258
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Teaching Skin Self-Examination to First-degree Relatives of Melanoma Patients Using Mobile App Technology
Status: WITHDRAWN
Conditions: Melanoma
Interventions: OTHER: Eviderma Smart Phone Teledermatology Application (Eviderma)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2, Single-Arm Study of Volociximab Monotherapy in Subjects With Platinum-Resistant Advanced Epithelial Ovarian Cancer or Primary Peritoneal Cancer
Status: TERMINATED
Conditions: Ovarian Cancer|Peritoneal Neoplasms
Interventions: DRUG: Volociximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rollover Study of Weekly Paclitaxel (BMS-181339) in Patients With Advanced or Recurrent Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Difference of Preoperative Related Parameters in Children With or Without Microcornea Within Less Than One Year Old
Status: COMPLETED
Conditions: Microcornea Within One Year of Age
Interventions: DEVICE: Collect ocular biological parameters including age, corneal diameter, eye axis, intraocular pressure, steep&flat axis of corneal curvature, corneal thickness, lens thickness, anterior chamber depth
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase III Trial of Primary Radio- or Chemotherapy in Malignant Astrocytoma of the Elderly
Status: COMPLETED
Conditions: Glioblastoma|Anaplastic Astrocytoma
Interventions: DRUG: Temozolomide|RADIATION: Radiotherapy of the partial brain.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 12-Week Study To Assess The Safety Of Fluticasone Propionate/Salmeterol 100/50 Hydrofluoroalkane (HFA) Versus Fluticasone Propionate 100 HFA In Children With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: fluticasone propionate|DRUG: fluticasone propionate/salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploration of New Nursing Models for Urological Surgery
Status: COMPLETED
Conditions: Urological Nursing
Interventions: PROCEDURE: high-quality nursing|PROCEDURE: Clinical Care Pathway|PROCEDURE: Roy Adaptation Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Pain Related to Bone Fracture
Status: RECRUITING
Conditions: Bone Fracture|Fresh Fracture
Interventions: DEVICE: Sustained Acoustic Device with 2.5% Diclofenac Patch|DRUG: 2.5% Diclofenac Patches
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Assessment of Myocardial Ischemia by Intracoronary Electrocardiogram
Status: COMPLETED
Conditions: Coronary Artery Disease|Stable Angina|Coronary Artery Stenosis|Ischemia
Interventions: DIAGNOSTIC_TEST: Functional Assessment of Myocardial Ischemia by icECG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Impact of Baby-friendly Hospital Initiative to Breastfeeding, Breastfeeding Counselling and Breastfeeding Attitudes
Status: COMPLETED
Conditions: Breastfeeding
Interventions: OTHER: Baby-friendly Hospital Initiative
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Infant Special Program for In Hospital Resuscitation Education in the Delivery Room
Status: COMPLETED
Conditions: Hypoxia, in Liveborn Infant|Neonatal Asphyxia|Neonatal Bradycardia
Interventions: OTHER: Educational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study Investigating the Effect of Montelukast in Patients With Seasonal Allergic Rhinitis (MK-0476-192)(COMPLETED)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: montelukast sodium|DRUG: Comparator: loratadine|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Burden of Anemia in Inflammatory Bowel Disease: Therapeutic Trial
Status: UNKNOWN
Conditions: Iron Deficiency Anemia|Inflammatory Bowel Diseases
Interventions: DRUG: Sucrosomial iron|DRUG: Ferric Gluconate|DRUG: Ferric carboxymaltose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimization of Intradialytic Hypotension Using Cardiography-Guided Intervention
Status: UNKNOWN
Conditions: Intradialytic Hypotension
Interventions: DEVICE: pressure stockings|DRUG: Midodrine|OTHER: pressure stockings and midodrine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy Versus Eplerenone: Treatment Trial for Chronic Central Serous Chorioretinopathy
Status: UNKNOWN
Conditions: Chronic Central Serous Chorioretinopathy
Interventions: DRUG: Eplerenone|OTHER: Photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effects of Ultrasound Versus Fluoroscopy for Sacroiliac Joint Injections
Status: COMPLETED
Conditions: Sacroiliitis
Interventions: PROCEDURE: Active comparator: Fluoroscopic Guided SIJ injection|PROCEDURE: Ultrasound Guided Sacroiliac Joint Injection|DEVICE: Havel's Inc. EchoStim (facet tip) 21 Gauge 4" needle|DEVICE: SonoSite S-nerve|DEVICE: iohexol|DRUG: triamcinolone/lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-Volume Study of a Treatment for Elevated IOP Due to Open-Angle Glaucoma or Ocular Hypertension
Status: TERMINATED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Anecortave Acetate Sterile Suspension, 6 mg/mL|DRUG: Anecortave Acetate Sterile Suspension, 3.75 mg/mL|DRUG: Anecortave Acetate Sterile Suspension, 96 mg/mL|DRUG: Anecortave Acetate Sterile Suspension, 60 mg/ML|OTHER: Anecortave Acetate Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Very Low Frequency Magnetic Fields in the Treatment of Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DEVICE: Very Low Frequency Magnetic Fields|DEVICE: Very Low Frequency Magnetic Fields
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Paediatric Resident Complex Care Curriculum RCT
Status: COMPLETED
Conditions: Complex Care|Medical Education|Pediatric Residents|Children With Medical Complexity
Interventions: OTHER: Complex Care Curriculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of Echogenic and Nonechogenic Needles in Ultrasound Guided Infraclavicular Brachial Plexus Block
Status: COMPLETED
Conditions: Upper Extremity Injury Trauma
Interventions: DEVICE: Echogenic needle - Pajunk sonoplex echogenic needle|DEVICE: Non Echogenic needle - Stimuplex Braun Nonechogenic needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase I Study of Umbilical Cord Blood Transplantation Followed by Third Party Thymus Transplantation
Status: TERMINATED
Conditions: Stem Cell Transplantation
Interventions: BIOLOGICAL: Thymic Transplantation for Recipients of UCB transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ⅰ/Ⅱ Study of SHR2554 in Combination With SHR1701 in Patients With Advanced Solid Tumors and B-cell Lymphomas
Status: RECRUITING
Conditions: Solid Tumor|Lymphoma
Interventions: DRUG: SHR2554+SHR1701|DRUG: SHR1701
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Administration of Surfactant Through an Instillation Device Infasurf® (Calfactant) in Neonates- A Pilot Study
Status: SUSPENDED
Conditions: RDS of Prematurity|Surfactant Protein B Deficiency|Chronic Lung Disease
Interventions: COMBINATION_PRODUCT: surfactant airway device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The NIH Exercise Therapy for Advanced Lung Disease Trials: Response and Adaptation to Aerobic Exercise in Patients With Interstitial Lung Disease
Status: COMPLETED
Conditions: Interstitial Lung Disease|Idiopathic Pulmonary Fibrosis|Interstitial Pneumonitis|Desquamative Interstitial Pneumonia
Interventions: OTHER: Aerobic Exercise Training (AET)|OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Efficacy of Local Infiltration Analgesia for Postoperative Pain Management After Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Primary Total Knee Arthroplasty
Interventions: PROCEDURE: Local infiltration analgesia with local anesthetic|PROCEDURE: Local infiltration analgesia without local anesthetic|DEVICE: Needle|DRUG: Solution with local anesthetic|DRUG: Solution without local anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gluten Sensitivity in Non-Celiac Patients
Status: COMPLETED
Conditions: Gluten Sensitivity
Interventions: DIETARY_SUPPLEMENT: gluten|DIETARY_SUPPLEMENT: rice starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Threonine Requirement in Adult Males With Crohn's Disease Using IAAO
Status: RECRUITING
Conditions: Crohn Disease|IBD
Interventions: OTHER: Dietary Intakes (Reference protein drinks (Scandishake, Solcarb, Beneprotein) and cookies)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Of Hepatic Impairment On AG-013736 Pharmacokinetics
Status: COMPLETED
Conditions: Hepatic Insufficiency
Interventions: DRUG: AG-013736|DRUG: AG-013736|DRUG: AG-013736
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk Factors for Shoulder Joint Motion Restriction
Status: UNKNOWN
Conditions: Breast Cancer Survivors
Interventions: OTHER: measurement of tissue stiffness (N/m)|OTHER: measurement of passive muscle tone (Hz)|OTHER: measurement of creep of tissue|OTHER: measurement of the range of shoulder joint motion|OTHER: measurement of skin temperature|OTHER: measurement of pain|OTHER: measurement of pain pressure threshold|OTHER: measurement of grip strength
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessing Screening Plus Brief Intervention's Resulting Efficacy (ASPIRE) to Stop Drug Use
Status: COMPLETED
Conditions: Drug Usage|Drug Abuse|Drug Dependence
Interventions: BEHAVIORAL: Standard Brief Intervention|BEHAVIORAL: Enhanced Brief Intervention|BEHAVIORAL: Control: Information and Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrapartum Epidural Catheter Displacement: Dressing Methods
Status: COMPLETED
Conditions: Analgesia, Obstetrical
Interventions: DEVICE: Tegaderm dressing + catheter support pad|DEVICE: Tegaderm dressing + Steri-strip dressing|DEVICE: Tegaderm dressing only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Docetaxel and Carboplatin With or Without Trastuzumab Before Surgery in Treating Women With Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: carboplatin|DRUG: docetaxel|BIOLOGICAL: trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Bimatoprost Solution in Treating Eyelash Loss or Hypotrichosis in Children
Status: COMPLETED
Conditions: Eyelash Hypotrichosis|Alopecia Areata
Interventions: DRUG: bimatoprost ophthalmic solution 0.03%|DRUG: Vehicle Sterile Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ciprofloxacin Dry Powder for Inhalation in Non-cystic Fibrosis Bronchiectasis (Non-CF BE)
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: DRUG: Ciprofloxacin DPI (BAYQ3939)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Docetaxel With Cisplatin and TS-ONE for Gastric Cancer With Peritoneal Carcinomatosis
Status: COMPLETED
Conditions: Gastric Cancer|Peritoneal Carcinomatosis
Interventions: DRUG: Intraperitoneal docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Spermotrend Food Supplement in the Treatment of Male Infertility
Status: COMPLETED
Conditions: Male Infertility|Benign Prostatic Hyperplasia|Spermatogenesis and Semen Disorders
Interventions: DIETARY_SUPPLEMENT: Spermotrend
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Dose Interferon Alfa in Treating Patients With Stage II or Stage III Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: interferon alfa-2b|OTHER: observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infant Formula in Infants and Children With Cow's Milk Allergy
Status: NOT_YET_RECRUITING
Conditions: Cow's Milk Allergy
Interventions: OTHER: Experimental Extensively Hydrolyzed Formula|OTHER: Placebo Extensively Hydrolyzed Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase I/II Study of U3-1402 in Subjects With Human Epidermal Growth Factor Receptor 3 (HER3) Positive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Patritumab Deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association Between EHG and Risk of Preterm Delivery in Women Hospitalized for Threatened Premature Delivery
Status: COMPLETED
Conditions: Preterm Birth
Interventions: OTHER: Electrical recording of uterine activity by EHG either directly at the emergency or at the hospitalization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: 68Ga-PSMA-11 PET/CT in Patients With Various Types of Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Positron-Emission Tomography
Interventions: DRUG: 68Ga-PSMA-11
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Regression of Liver Fibrosis by Tenofovir Alafenamide (TAF)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Hepatitis B
Interventions: DRUG: Tenofovir alafenamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Limit Physiologic Intestinal FDG Uptake Uptake on PET-CT Scans
Status: COMPLETED
Conditions: Intestinal FDG Uptake
Interventions: DRUG: Rifaximin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Growth Hormone Secretagogue MK-0677's Effect on Lean Body Mass in Chronic Kidney Disease Stage 4/5 Subjects
Status: WITHDRAWN
Conditions: Chronic Kidney Disease|Kidney Disease
Interventions: DRUG: MK-0677|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Subscapularis Indocyanine Green Perfusion Pilot Study
Status: COMPLETED
Conditions: Shoulder Pain|Shoulder Arthritis|Shoulder Arthroplasty
Interventions: PROCEDURE: Perfusion with Indocyanine green
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 3, Sciatic Nerve Block With EXPAREL for Subjects Undergoing Bunionectomy
Status: COMPLETED
Conditions: Bunionectomy|Hallux Valgus
Interventions: DRUG: Bupivacaine liposome injectable suspension 266 mg|DRUG: Bupivacaine HCl|DRUG: Bupivacaine liposome injectable suspension 133 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Association Between Temporomandibular Disorders and Sacroiliac Joint Dysfunction
Status: RECRUITING
Conditions: Temporomandibular Joint Disorders|Temporomandibular Disorder
Interventions: OTHER: Orofacial Manual Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Long-Term Safety and Efficacy of Bempedoic Acid (CLEAR Harmony OLE)
Status: COMPLETED
Conditions: Hypercholesterolemia|Atherosclerotic Cardiovascular Disease
Interventions: DRUG: bempedoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Immune Response and Safety of Prophylactic Vaccines in Patients Treated for Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: BIOLOGICAL: prophylactic vaccine (tetanus, diphtheria, pertussis, poliomyelitis, influenza, hepatitis A, hepatitis B, tick-borne encephalitis, meningococcal, pneumococcal)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Plaque Reduction Sesame Oil
Status: COMPLETED
Conditions: Dental Plaque|Gingivitis|Oral Microbial Colonization
Interventions: OTHER: sesame oil|OTHER: distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Urate Lowering Therapy of Febuxostat Compared to Allopurinol on Cardiovascular Risk in Patients With Gout
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: Febuxostat 80/120mg/day|DRUG: Allopurinol 100 up to 600mg/day|DRUG: Colchicine|DRUG: Naproxen|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Osteochondral Lesions Under 15mm2 of the Talus; is Iliac Crest Bone Marrow Aspirate Concentrate the Key to Success?
Status: UNKNOWN
Conditions: Osteochondral Lesion of Talus
Interventions: BIOLOGICAL: BMS + Bone Marrow Aspirate Concentrate|PROCEDURE: BMS alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Community-based Follow-up of Severely Malnourished Children
Status: COMPLETED
Conditions: Malnourished Children
Interventions: BEHAVIORAL: C-C|OTHER: C-SF|OTHER: As C-C with additional psychosocial stimulation (PS) (C-PS)|OTHER: As C-C but with both SF & PS (C-SF+PS)|OTHER: H-C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of IPGDP Regimen Chemotherapy in Patients With Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type
Status: UNKNOWN
Conditions: Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type
Interventions: OTHER: chemotherapy followed by radiotherapy|OTHER: radiotherapy followed by chemotherapy|DRUG: IPGDP regimen chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Peginterferon a-2a in Patients of Chronic Hepatitis B With Spontaneous Decline of HBV DNA
Status: COMPLETED
Conditions: Antiviral Treatment of Chronic Hepatitis B
Interventions: DRUG: Pegasys(Roche)|DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Ibuprofen on Inflammatory Responses in Patients Undergoing Surgery With General Anesthesia.
Status: TERMINATED
Conditions: Inflammatory Response
Interventions: DRUG: Ibuprofen|DRUG: Placebo/Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Injections of Botulinum Toxin A in Treatment of Patients With Detrusor Overactivity and Impaired Contractility
Status: COMPLETED
Conditions: Botulinum Toxins, Type A
Interventions: DRUG: Botulinum toxin A|DRUG: Botulinum toxin A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NOPHO-AML 2004 Study for Children With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Gemtuzumab ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CTLA-4 /PD-L1 Blockade Following Transarterial Chemoembolization (DEB-TACE) in Patients With Intermediate Stage of HCC (Hepatocellular Carcinoma) Using Durvalumab and Tremelimumab
Status: ACTIVE_NOT_RECRUITING
Conditions: Intermediate Stage of Hepatocellular Carcinoma|Hepatocellular Carcinoma
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab (Cohort A dose)|DRUG: Tremelimumab (Cohort B dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib/Adriamycine/Melfalan/Prednisone (VAMP)/Thalidomide/Cyclophosphamide/Dexamethasone (TaCyDex) or Bortezomib/Melfalan/Prednisone (V-MP)/TaCyDex) in Refractary or Relapsed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib|DRUG: Thalidomide|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neural Mechanisms of Change During the Treatment of Alcohol Use Disorders With Prazosin
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: Prazosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bempegaldesleukin (NKTR-214) With Radiation and Anti-PD-1 Immunotherapy for Head and Neck Squamous Cell Carcinoma
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DRUG: NKTR-214|DRUG: anti-PD-1 therapy|RADIATION: Palliative Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Age and Prior Immunity on Response to H1N1 Vaccines in Children
Status: WITHDRAWN
Conditions: 2009 H1N1 Influenza
Interventions: BIOLOGICAL: Live Attenuated H1N1 Influenza Vaccine|BIOLOGICAL: Influenza A (H1N1) 2009 Monovalent Vaccine|BIOLOGICAL: Influenza A (H1N1) 2009 Monovalent Vaccine/ Influenza A (H1N1) Monovalent Vaccine Live
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: THE ROLE OF CARDIAC MARKERS IN HYPOXIC ISCHEMIC ENCEPHALOPATHY IN LONG-TERM NEURODEVELOPMENTAL FOLLOW UP
Status: UNKNOWN
Conditions: Hypoxic-Ischemic Encephalopathy|Newborn Morbidity
Interventions: OTHER: no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pivotal Study of the Safety and Effectiveness of Arformoterol in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Arformoterol tartrate inhalation solution|DRUG: Arformoterol tartrate inhalation solution|DRUG: Arformoterol tartrate inhalation solution|DRUG: Salmeterol MDI|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravitreal VEGF-Trap Eye on Polypoidal Choroidal Vasculopathy
Status: COMPLETED
Conditions: Exudative Age-related Macular Degeneration|Polypoidal Choroidal Vasculopathy
Interventions: DRUG: aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Drug Interaction Between Teneligliptin and Empagliflozin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Teneligliptin|DRUG: Empagliflozin|DRUG: Teneligliptin and Empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission
Status: RECRUITING
Conditions: Acute HIV Infection
Interventions: BIOLOGICAL: VRC07-523LS|BIOLOGICAL: PGT121.414.LS|OTHER: Placebo|DRUG: ART
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Helicobacter Pylori Eradication, Anti-D and Danazol Combination in Steroid Dependant or Refractory Immune Thrombocytopenia (ITP)
Status: UNKNOWN
Conditions: Thrombocytopenia
Interventions: OTHER: Steroid refractory ITP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Pharmacokinetics and Safety of MK-8808 (MK-8808-002)
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: MK-8808|BIOLOGICAL: MabThera® (rituximab)|DRUG: Methotrexate|BIOLOGICAL: Rituxan® (rituximab)|DRUG: Methylprednisolone|DRUG: Acetaminophen|DRUG: Loratadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of IHAT in Iron Deficient Pre-menopausal Woman
Status: NOT_YET_RECRUITING
Conditions: Iron-deficiency
Interventions: DRUG: Low dose IHAT|DRUG: High Dose IHAT|DRUG: Carob flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of LED Phototherapy for Musculoligamentous Lesions
Status: COMPLETED
Conditions: Tendinopathy|Sprains and Strains|Muscle Spasm|Epicondylitis|Fasciitis
Interventions: DEVICE: Red and near infrared LED phototherapy device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Pharmacokinetics of Tinzaparin During Slow Low Efficient Daily Dialysis in Intensive Care Patients
Status: RECRUITING
Conditions: Acute Kidney Injury|Renal Replacement Therapy|Anticoagulants
Interventions: DRUG: Tinzaparin continuous infusion|DRUG: Tinzaparin bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Effectiveness of the Medtronic Resting Heart Bypass System in Heart Surgery Patients
Status: COMPLETED
Conditions: Coronary Artery Bypass Surgery|Cardiopulmonary Bypass
Interventions: DEVICE: Medtronic Resting Heart Bypass System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing the Efficacy and Safety of Octreotide Acetate in Patients With Acromegaly, With Micro or Macroadenomas
Status: TERMINATED
Conditions: Acromegaly
Interventions: DRUG: Octreotide acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study for T-1201 Injection 100 mg Kit in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: T-1201 Injection 100 mg Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Pharmacokinetics of Azithromycin Eye Drops in Healthy Volunteers
Status: UNKNOWN
Conditions: Bacterial Conjunctivitis
Interventions: DRUG: azithromycin eye drops by essex|DRUG: azithromycin eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Group Patient Education on Glycemic Control Among People Living With Type 2 Diabetes in Vietnam
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: OTHER: patient education and self-management intervention in a low-resource setting on diabetes knowledge and levels of blood glucose control|OTHER: Usual diabetes care alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of OLP-1002 Injections for Reducing Moderate to Severe Pain Due to Osteoarthritis in Hip and/or Knee Joint
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: OLP-1002
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liraglutide Treatment to Patients With Severe Renal Insufficiency
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|End-stage Renal Disease
Interventions: DRUG: Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reduced Intensive Idarubicin and Cytarabine Plus Venetoclax as First-line Treatment for Adults AML and MDS
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: idarubicin|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ambulatory vs Office BP Management Usual Care for Diagnosing and Managing Hypertension: A Pilot Study
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Amlodipine|DRUG: Chlorthalidone|DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Early Weight Bearing on Supracondylar Distal Femur Fractures in Elderly Patients
Status: COMPLETED
Conditions: Distal Femur Fractures
Interventions: OTHER: Non Weight bearing|OTHER: Early Weight Bearing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Immediate Release Tablet
Status: COMPLETED
Conditions: Invasive Aspergillosis
Interventions: DRUG: F901318 SDD|DRUG: F901318 IR|DRUG: F901318 IR Fasting|DRUG: F901318 IR Fed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Whether BI 456906 (Survodutide) Influences the Amount of Bupropion, Caffeine and Midazolam in the Blood in People With Overweight or Obesity
Status: NOT_YET_RECRUITING
Conditions: Overweight|Obesity
Interventions: DRUG: Survodutide|DRUG: Bupropion|DRUG: Caffeine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined T Cell Depleted Haploidentical Peripheral Blood Stem Cell and Unrelated Umbilical Cord Blood Transplantation in Patients With Hematologic Malignancies Using a Total Lymphoid Irradiation Based Preparative Regimen
Status: TERMINATED
Conditions: Hematological Malignancies
Interventions: DRUG: Cyclophosphamide|DRUG: Thiotepa|DRUG: Fludarabine|DRUG: Melphalan|DRUG: Mesna|BIOLOGICAL: G-CSF|DRUG: Mycophenolate mofetil|DRUG: Tacrolimus|DRUG: Methylprednisolone|RADIATION: Total lymphoid irradiation|BIOLOGICAL: Lymphocyte infusions|DEVICE: CliniMACS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization of Complex Pulse Shapes in Deep Brain Stimulation for Movement Disorders Using EEG and Local Field Potential Recordings
Status: COMPLETED
Conditions: Parkinson Disease|Essential Tremor
Interventions: DEVICE: Boston Scientific: Study tool computer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Intradialytic Continuous Versus Interval Aerobic Exercises on Quality of Life in Patients With Chronic Renal Failure.
Status: COMPLETED
Conditions: Chronic Kidney Diseases
Interventions: OTHER: low- to moderate-continuous intensity cycling exercises:|OTHER: moderate- to high-interval intensity cycling exercises|OTHER: hemodialysis sessions only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sustainability of Vitamin D Levels After Repletion With Ergocalciferol In Chronic Kidney Disease Stage 5D
Status: TERMINATED
Conditions: Vitamin D Deficiency|Renal Failure Chronic Requiring Hemodialysis
Interventions: DRUG: Ergocalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Venotrain UlcerteC Venous Compression Device in the Treatment of Venous Ulcers in Daily Practice
Status: ACTIVE_NOT_RECRUITING
Conditions: Venous Leg Ulcer
Interventions: OTHER: Patients with venous leg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PSB202 in Patients With Previously Treated-, Relapsed-, Indolent B-Cell Malignancies
Status: UNKNOWN
Conditions: Follicular Lymphoma|Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma|Waldenstrom Macroglobulinemia|Marginal Zone Lymphoma|Mantle Cell Lymphoma|Indolent Lymphoma|Refractory B-Cell Lymphoma|MALT Lymphoma
Interventions: DRUG: PSB202
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Intratumoral Injection of CAR-T Cells in the Treatment of Advanced Liver Tumors
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma , Cholangiocarcinoma
Interventions: BIOLOGICAL: anti-GPC3 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Constituents in Exhaled Breath and Room Air From Use of E-vapor Products and Conventional Cigarettes
Status: COMPLETED
Conditions: Second Hand Tobacco Smoke
Interventions: OTHER: JUUL|OTHER: VUSE Solo|OTHER: Conventional Cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Recormon (Epoetin Beta) in Anemic Patients With Non-Myeloid Malignancy
Status: TERMINATED
Conditions: Anemia
Interventions: DRUG: Epoetin Beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cytochrome P 450 3A4 Inhibition by Itraconazole on the Single Oral Dose Pharmacokinetics of Cilobradine
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cilobradine, low dose|DRUG: Cilobradine, high dose|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Infliximab Versus Methotrexate in the Treatment of Moderate to Severe Psoriasis (Study P04271AM2)(COMPLETED)
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: infliximab|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carfilzomib in Treating Patients With Multiple Myeloma in First Relapse or Refractory to First-Line Therapy
Status: TERMINATED
Conditions: Refractory Multiple Myeloma
Interventions: DRUG: carfilzomib|DRUG: dexamethasone|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Erythropoietin in Premature Infants on White Matter Lesions and Neurodevelopmental Outcome
Status: UNKNOWN
Conditions: Premature Infants|Intracranial Hemorrhages|Periventricular Leukomalacia|Cerebral Palsy
Interventions: DRUG: Erythropoietin|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Platelets Rich Plasma (APRP) Treatment Vs Saline Dressing for the Management of Diabetic Foot Ulcer
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: OTHER: Autologous Platelets Rich Plasma Treatment|OTHER: Conventional Saline dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Phosphorylated Metabolism Profile as Predictive Biomarker of Cognitive Decline in Memory Complaint.
Status: COMPLETED
Conditions: Memory Complaint|Alzheimer Disease|Phosphorylated Metabolism Profile|Magnetic Resonance Spectroscopy
Interventions: OTHER: Additional sequence performed during MRI scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Promoting Activity in Cancer Survivors
Status: COMPLETED
Conditions: Physical Activity|Breast Cancer
Interventions: BEHAVIORAL: Physical activity education|BEHAVIORAL: Facility access|BEHAVIORAL: Supervised exercise sessions|BEHAVIORAL: Self-monitoring (Fitbit)|BEHAVIORAL: Active living counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase III Study Comparing the Immunogenicity of 9-valent HPV Recombinant Vaccine and Gardasil-9
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Cancer|Genital Wart|CIN|VIN|Papillomavirus Infections
Interventions: BIOLOGICAL: Zerun HPV-9|BIOLOGICAL: GARDASIL ®9
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I/II Clinical Trial for Treatment of Aromatic L-amino Acid Decarboxylase (AADC) Deficiency Using AAV2-hAADC
Status: COMPLETED
Conditions: Aromatic L-amino Acid Decarboxylase (AADC) Deficiency
Interventions: DRUG: gene therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Bandage and Surgical Stent as Palatal Donor Site Dressing After Free Gingival Graft Surgery.
Status: COMPLETED
Conditions: Palate; Wound
Interventions: DEVICE: Laser Bandage|PROCEDURE: Hemostatic agent with surgical stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerability of Quinagolide in a Dose-titration Regimen in Oocyte Donors at Risk of Developing Ovarian Hyperstimulation Syndrome
Status: COMPLETED
Conditions: Ovarian Hyperstimulation Syndrome
Interventions: DRUG: Quinagolide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Elastography Evaluation of Myocardial Stiffness in Elderly Patients With Isolated Diastolic Heart Failure: New Diagnostic Tool?
Status: RECRUITING
Conditions: Cardiovascular Diseases in Old Age
Interventions: DIAGNOSTIC_TEST: SuperSonic image
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment Comparison for Undergraduate College Students With Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury|Concussion, Brain
Interventions: BEHAVIORAL: Dynamic Coaching Model|BEHAVIORAL: Apprenticeship Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cholecalciferol Supplementation in Strengthening Inspiratory Muscles in Cholecalciferol-Deficient Patients With Chronic Obstructive Pulmonary Disease
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease|Muscle Weakness
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol|OTHER: Laboratory Biomarker Analysis|DIETARY_SUPPLEMENT: Multivitamin|OTHER: Placebo|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Hemin to Prevent Post-ERCP (Endoscopic Retrograde Cholangiopancreatography) Acute Pancreatitis
Status: COMPLETED
Conditions: Post-ERCP Acute Pancreatitis
Interventions: DRUG: Hemin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PSMA-PET Imaging for Advanced ACC/SDC
Status: COMPLETED
Conditions: Salivary Gland Cancer|Adenoid Cystic Carcinoma|Salivary Duct Carcinoma
Interventions: DIAGNOSTIC_TEST: PSMA-PET/CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hypotension After Anesthetic Induction With Remimazolam in Elderly
Status: NOT_YET_RECRUITING
Conditions: Hypotension
Interventions: DRUG: Bolus of remimazolam|DRUG: Continuous infusion of remimazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Adherence to Lifestyle Changes for Age-related Macular Degeneration
Status: ACTIVE_NOT_RECRUITING
Conditions: Age-Related Macular Degeneration
Interventions: COMBINATION_PRODUCT: Standard lifestyle recommendations + dietary supplementation|COMBINATION_PRODUCT: Risk profiling|BEHAVIORAL: Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ablative Chemoembolization for Unresectable and Large Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Carcinoma, Hepatocellular
Interventions: PROCEDURE: Ablative chemoembolization (ACE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Validation of Tele-stethoscope System Digital
Status: COMPLETED
Conditions: Respiratory Disorder|Heart Disorder
Interventions: DEVICE: Heart and Respiratory Auscultation of an open real-time tele-stethoscopy system (EHAS-Fundatel digital stethoscope)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Pretreatment With Dydrogesterone Vs Combined Estradiol Valerate and Dydrogestrone on Clinical Pregnancy Outcome of ICSI in PCOS Patients"
Status: UNKNOWN
Conditions: PCOS|ICSI
Interventions: DRUG: dydrogesterone 20 mg /d (Duphaston, Abott Healthcare , Egypt)|DRUG: estradiol valerate 2 mg /d (white tablets of cycloprognova, Bayer Shering, Germany)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tactile and Kinesthetic Stimulation on Very Low Birth Weight Preterm Infants
Status: COMPLETED
Conditions: Preterm Birth
Interventions: BEHAVIORAL: Tactile stimulus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT