pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Compare Early Use of Vinorelbine and Maintenance Therapy for Patients With High Risk Rhabdomyosarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Alveolar Rhabdomyosarcoma|Botryoid-Type Embryonal Rhabdomyosarcoma|Embryonal Rhabdomyosarcoma|Metastatic Embryonal Rhabdomyosarcoma|Metastatic Rhabdomyosarcoma|Solid Alveolar Rhabdomyosarcoma|Spindle Cell Rhabdomyosarcoma|Spindle Cell/Sclerosing Rhabdomyosarcoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Bone Scan|PROCEDURE: Computed Tomography|DRUG: Cyclophosphamide|BIOLOGICAL: Dactinomycin|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|RADIATION: Radiation Therapy|DRUG: Vincristine Sulfate|DRUG: Vinorelbine Tartrate|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Part-time Patch Therapy for Treatment of Intermittent Exotropia
Status: UNKNOWN
Conditions: Intermittent Exotropia
Interventions: OTHER: patch therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abbreviated Protocol for Two-Stage Exchange
Status: COMPLETED
Conditions: Prosthetic Joint Infection
Interventions: COMBINATION_PRODUCT: VT-X7 Treatment System with Tobramycin Sulfate|DRUG: Standard of Care|PROCEDURE: Two-stage exchange arthroplasty|COMBINATION_PRODUCT: VT-X7 Treatment System with Vancomycin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: High-Intensity Aerobic Interval Training in Testicular Cancer Survivors
Status: COMPLETED
Conditions: Cardiovascular Diseases|Testicular Neoplasms
Interventions: BEHAVIORAL: High-intensity aerobic interval exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fibergraft Interbody Fusion Retrospective
Status: COMPLETED
Conditions: Degenerative Disc Disease|Degenerative Spondylolisthesis|Spinal Degeneration|Spinal Stenosis
Interventions: RADIATION: Computed Tomography (CT) Scan of the Lumbar Spine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Evaluation of MEBO Ointment and Topical Diltiazem Ointment in the Treatment of Acute Anal Fissure
Status: RECRUITING
Conditions: Anal Fissure
Interventions: DRUG: Diltiazem|DRUG: Mebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Strategies During Exposure to Pain in an Experimental Design
Status: COMPLETED
Conditions: Pain, Acute
Interventions: BEHAVIORAL: Exposure therapy (according to habituation approach)|BEHAVIORAL: Exposure therapy (according to inhibitory learning approach)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Deployment Capability and Accuracy of an Outside the Scope (OTS), Detachable Catheter System for Ablation of Peripheral Lung Lesions: An Ex-Vivo Human Lung Model Study
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DEVICE: Outside the Scope (OTS), Detachable Catheter System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BAL0891 in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|TNBC - Triple-Negative Breast Cancer|Gastric Cancer
Interventions: DRUG: BAL0891|COMBINATION_PRODUCT: Carboplatin|COMBINATION_PRODUCT: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraarticular Dextrose Prolotherapy for Symptomatic Knee Osteoarthritis
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DRUG: Placebo|DRUG: Dextrose prolotherapy (DPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DermACELL AWM® in Chronic Wagner Grade 3/4 Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer|Lower Extremity Wound
Interventions: OTHER: DermACELL AWM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Active Video Game-Based Exercise Training and Stability Training After AIS Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Adolescent Idiopathic Scoliosis|Spinal Fusion
Interventions: OTHER: Active Video Based Exercises|OTHER: Stabilization and Strengthening Exercises|OTHER: Waiting List-Spine protection principles training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Posturography-assisted Vestibular Retraining for Stable Unilateral Vestibular Deficit
Status: ACTIVE_NOT_RECRUITING
Conditions: Dizziness|Equilibrium; Disorder, Labyrinth|Inner Ear Injury|Inner Ear Disease
Interventions: DEVICE: Vestibular retraining with dynamic posturography|BEHAVIORAL: At-home rehabilitation exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Monovisc® Injection for Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Monovisc®|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Descriptive Study of Baseline Characteristics, Clinical Outcomes, and Treatment Patterns of HR+/HER2- Advanced or Metastatic Breast Cancer Patients Treated With Alpelisib Plus Fulvestrant Who Have Received Fulvestrant in Any Prior Line of Therapy
Status: COMPLETED
Conditions: HR+/HER2- Advanced or Metastatic Breast Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Sliding Hip Screw to Intra Medullary Nailing in the Treatment of Intertrochanteric Hip Fracture
Status: UNKNOWN
Conditions: Hip Fractures|Gait, Unsteady|Function
Interventions: DEVICE: TFNA IM Nail|DEVICE: Sliding hip screw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiological and Clinical Efficacy of a Hybrid Spinal Implant ("Topping Off"): a Mono-center, Prospective Clinical Trial
Status: COMPLETED
Conditions: Spine Surgery
Interventions: DEVICE: Dynesys DTO device (Zimmer Spine, Inc.)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Assess Effects of Self-Administered Nitrous Oxide (SANO) on Urodynamic Study (UDS) Parameters
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms
Interventions: DRUG: Self-Administered Nitrous Oxide|OTHER: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trial for the Treatment of Depression With Repetitive Transcranial Magnetic Stimulation (rTMS)
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DEVICE: Active Cervel Neurotech Multi-Coil Transcranial Magnetic Stimulator|DEVICE: Inactive Cervel Neurotech Multi-Coil Transcranial Magnetic Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: METHOD - Bone Marrow Derived Mononuclear Cells in Chronic Ischemic Disease
Status: TERMINATED
Conditions: Chronic Ischemic Heart Disease
Interventions: OTHER: intramyocardial injection of BM cells|OTHER: intramyocardial / intracoronary injection of BM cells|OTHER: Best medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Versus Transversus Abdominis Plane Block for Pain Control
Status: NOT_YET_RECRUITING
Conditions: Cesarean Section Complications
Interventions: PROCEDURE: Ultrasound-guided pain block|DEVICE: Ultrasound Machine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Kangaroo Mother Care Before Stabilisation Amongst Low Birth Weight Neonates in Africa
Status: COMPLETED
Conditions: Kangaroo Mother Care|Preterm Infant|Death; Neonatal|Hypothermia, Newborn
Interventions: OTHER: Kangaroo mother care|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Helping Veterans Quit Smoking by Improving Their Sleep
Status: TERMINATED
Conditions: Smoking
Interventions: BEHAVIORAL: Integrated Care|BEHAVIORAL: Cognitive-Behavioral Treatment for Insomnia|BEHAVIORAL: Desensitization Treatment for Insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study to Demonstrate the Safety and Feasibility of Plexisyl-AF in Patients Undergoing Coronary Artery Bypass Grafting (CABG)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Plexisyl-AF|OTHER: No Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Analgesic Efficacy of Inter Pleural Ropivacaine Road in Post Thoracotomy Pain for Oncologic Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Cancer
Interventions: DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetic Foot Ulcer Research Study
Status: RECRUITING
Conditions: Diabetic Foot Ulcer|Diabetic Foot Ulcer Neuropathic|Diabetic Foot Ulcer Ischemic
Interventions: DEVICE: Wound Dressing|DEVICE: NHS Standard Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Sensitivity to Different Chemotherapy Regimens in Platinum-Partial Sensitive Recurrent Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer
Interventions: DRUG: Doxorubicin Hydrochloride Liposome Injection+carboplatin|DRUG: paclitaxel +carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Confirmation Study of Oral Clofarabine for Adult Patients Previously Treated for Myelodysplastic Syndromes (MDS)
Status: COMPLETED
Conditions: Myelodysplastic Syndromes|Secondary Acute Myeloid Leukemia (AML)
Interventions: DRUG: Clofarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional and Neuroplastic Effects of HABIT-ILE in Children With Bilateral Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: BEHAVIORAL: Hand-Arm Bimanual Intensive Therapy Including Lower Extremities|BEHAVIORAL: Hand-Arm Bimanual Intensive Therapy Including Lower Extremities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trials of Ventilation Assisted Substance Elimination Via the Lung - Ethanol (VASEL - Ethanol)
Status: UNKNOWN
Conditions: Alcohol Intoxication
Interventions: DEVICE: ClearMateTM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predicting Response to Iron Supplementation in Patients With Active Inflammatory Bowel Disease
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases|Iron-deficiency|Iron Deficiency Anemia
Interventions: DRUG: Intravenous iron|DRUG: Ferric maltol|DRUG: Ferrous fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study of TQH2722 Injection in the Treatment of Moderate to Severe Atopic Dermatitis
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: TQH2722 injection 300mg-150mg|DRUG: TQH2722 injection 600mg-300mg|DRUG: TQH2722 injection 900mg-450mg|DRUG: TQH2722 injection matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Tipranavir Soft Elastic Capsules (SEDDS) and Ritonavir and Their Effects on Cytochrome P-450 (3A4) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TPV low 1|DRUG: TPV low 2|DRUG: TPV medium|DRUG: TPV high 1|DRUG: TPV high 2|DRUG: RTV low|DRUG: Ritonavir high|DRUG: Radiolabelled erythromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Length of Hospital Stay in Laparoscopic Transabdominal Preperitoneal Vs. Open Mesh Repair in Inguinal Hernia: A Randomised Controlled Trial
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: PROCEDURE: hospital stay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MP0250 DARPin® Protein Plus Osimertinib in Patients With EGFR-mutated NSCLC
Status: TERMINATED
Conditions: EGFR-mutated NSCLC (Disorder)
Interventions: COMBINATION_PRODUCT: MP0250 DARPin® drug candidate, Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Open-Label Study Evaluating the Effect Of GW786034 In Subjects With Ovarian Cancer
Status: COMPLETED
Conditions: Peritoneal Cancer|Ovarian Cancer|Neoplasms, Ovarian|Fallopian Tube Cancer
Interventions: DRUG: GW786034
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adult Study Oxytocin - Behavioral
Status: COMPLETED
Conditions: Schizophrenia|Oxytocin|Social Cognition|Psychotic Disorders
Interventions: DRUG: Oxytocin|DRUG: Saline Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Multi-center Study Evaluating the Validity, Reliability, and Responsiveness of a New Female-specific Angina Questionnaire in Women With Chronic Angina Treated With Ranolazine Extended-release Tablets (CVT 3041)
Status: COMPLETED
Conditions: Chronic Angina
Interventions: DRUG: Ranolazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Comparison of Subcuticular Suture Versus Surgical Staples for Closure of Pfannenstiel Skin Incisions
Status: COMPLETED
Conditions: Pain, Postoperative|Gynecologic Surgical Procedures|Obstetric Surgical Procedures
Interventions: PROCEDURE: Subcuticular Suture|PROCEDURE: Surgical Staples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Phase II Trial in Patients With T1c Operable, HER2-positive Breast Cancer According to TOP2A Status
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: FEC100|DRUG: Docetaxel|DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga-P16-093 and 68Ga-PSMA-11 PET/CT Imaging in the Same Group of Primary Prostate Cancer Patients
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: 68Ga-P16-093|DRUG: 68Ga-PSMA-11
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Determination of ED90 of Intrathecal Lidocaine for Adequate Anesthesia for Elective Cervical Cerclage Surgery
Status: TERMINATED
Conditions: Pregnancy|Surgery|Pain
Interventions: DRUG: Lidocaine Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: High Clopidogrel Dose Versus Prasugrel and Ticagrelor in High Reactive Stable Patients
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Clopidogrel|DRUG: Prasugrel|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dexmedetomidine on Stress Response and Postoperative Analgesia
Status: COMPLETED
Conditions: Restlessness|Pain
Interventions: DRUG: dexmedetomidine|DRUG: saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Iron Long-Term Labelling Study Switzerland
Status: UNKNOWN
Conditions: Iron Absorption
Interventions: DRUG: Eisensulfat LOMAPHARM 50 mg|DRUG: Ferinject(R)|DIETARY_SUPPLEMENT: iron fortified biscuits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Computerized Attention Training for Individuals With Acquired Brain Injury
Status: COMPLETED
Conditions: Acquired Brain Injury|Stroke|Hemispatial Neglect
Interventions: BEHAVIORAL: Tonic and Phasic Attention Training|BEHAVIORAL: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose:
Clinical trial: Bioequivalence Study of Solifenacin Succinate & Mirabegron From Mirfenacin MR 5/50 mg Extended Release Tablets (Hikma Pharma, Egypt) Versus Vesicare 5 mg FCT & Betmiga 50 mg Prolonged-Release Tablets (Astellas Pharma Europe B.V, the Netherlands / Astellas Pharma Europe B.V, the Netherlands)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Vesicare (Solifenacin Succinate 5 mg) & Betmiga (Mirabegron 50 mg) (Reference first dose)|DRUG: Mirfenacin MR (Solifenacin Succinate 5 mg & Mirabegron 50 mg) (Test)|DRUG: Vesicare (Solifenacin Succinate 5 mg) & Betmiga (Mirabegron 50 mg) (Reference second dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Motor Cortex Stimulation for Chronic Neuropathic Pain
Status: UNKNOWN
Conditions: Neuropathic Pain|Facial Pain|Post-stroke Pain|Brachial Plexus Avulsion|Phantom Limb Pain of the Upper Extremities
Interventions: DEVICE: Motor Cortex Stimulation using SJM EonC Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Reactogenicity of ADACEL® (TdcP Vaccine) in Children and Adolescents 7 to 19 Years of Age
Status: COMPLETED
Conditions: Pertussis|Diphtheria
Interventions: BIOLOGICAL: Tetanus and diphtheria toxoids and acellular pertussis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Behavioral and Subjective Efficacy of Ramelteon in Subjects With a History of Polydrug Abuse
Status: COMPLETED
Conditions: Drug Abuse
Interventions: DRUG: Ramelteon, triazolam, and placebo (56 possible combinations total)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D, Insulin Resistance, and Cardiovascular Disease
Status: COMPLETED
Conditions: Vitamin D Deficiency|Insulin Resistance|Type 2 Diabetes Mellitus|Cardiovascular Disease|Hypertension
Interventions: DRUG: Vitamin D3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Ambient Light Multiple Myeloma Study
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DEVICE: Circadian Effective Lighting|DEVICE: Circadian Ineffective Lightning (CIL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a High Protein Breakfast on Appetite and Sleep in Young Adults
Status: SUSPENDED
Conditions: Appetite and General Nutritional Disorders
Interventions: BEHAVIORAL: HP-Beverage Breakfast|BEHAVIORAL: HP-Solid Breakfast|BEHAVIORAL: Breakfast Skipping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COach2Quit TRIAL: Assessing a Prototype Personal Carbon Monoxide Monitor for Smoking Cessation
Status: COMPLETED
Conditions: Smoking|Smoking Cessation
Interventions: DEVICE: Individualized carbon monoxide (iCO) monitor|OTHER: COach2Quit smartphone application|BEHAVIORAL: Cessation counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Insulin Therapy Reduce Post-Operative Inflammatory Response After Curative Colorectal Cancer Resection: Randomization Controlled Trial
Status: UNKNOWN
Conditions: Colon Cancer
Interventions: DRUG: Hyper insulinemic euglycemic clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Treatment With ABT-199 (Venetoclax) and Purine Analogues in Relapsed/Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia, in Relapse|Acute Myeloid Leukemia Refractory
Interventions: DRUG: Venetoclax|DRUG: 6-mercaptopurine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Administration Method of Cognitive Screening in Older Individuals With Hearing Loss
Status: COMPLETED
Conditions: Hearing Loss, Sensorineural|Cognitive Impairment
Interventions: OTHER: Auditory amplified|OTHER: Visual|OTHER: Auditory unamplified
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Mitapivat (AG-348) in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Placebo for Treatment A|DRUG: Mitapivat 100 mg|DRUG: Placebo for Treatment B|DRUG: Mitapivat 300 mg|DRUG: Placebo for Treatment C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Chronic Kidney Disease(CDK) Progression in Type 1 Diabetes With Long Term Use of Sodium-Glucose-coTransporter Inhibitors Avoiding Kidney hypOxia
Status: NOT_YET_RECRUITING
Conditions: Nephropathy|Diabetic Nephropathies|Diabetes Mellitus, Type 1|Albuminuria|Diabetic Complications Renal|Diabetic Complications Cardiovascular|Hypoxia
Interventions: DRUG: Sotagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Venetoclax in Combination With Chemotherapy in Pediatric Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Leukemia of Ambiguous Lineage
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Venetoclax|DRUG: Cytarabine|DRUG: Idarubicin|DRUG: Intrathecal Triple Therapy|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Approach in Intensive Care Unit Consciousness Assessment: FIVE Score
Status: NOT_YET_RECRUITING
Conditions: Postoperative Intracranial Hematoma|Postoperative Intracranial Haemorrhage|Supratentorial Cancer|Infratentorial Neoplasms|Arnold Chiari Malformation|Subarachnoid Hemorrhage|Traumatic Brain Injury|Epilepsy, Temporal Lobe|Cerebrovascular Event|Intensive Care Neurological Disorder|Coma|Unconsciousness|Assessment, Self
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|NSCLC|Lung Cancer|Breast Cancer|Esophageal Cancer|SCLC|Small Cell Lung Cancer|NPC|Nasopharyngeal Cancer
Interventions: DRUG: BL-B01D1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Supplementation With Glutamine and Exercise in Women With HIV/AIDS
Status: COMPLETED
Conditions: Glutamine; Metabolic Disorder|Physical Activity
Interventions: DIETARY_SUPPLEMENT: Glutamine and exercise|DIETARY_SUPPLEMENT: Maltodextrin and exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Fatherhood Focused Family Violence Education Program
Status: COMPLETED
Conditions: Domestic Violence
Interventions: BEHAVIORAL: Fatherhood Focused FVEP (F3)|BEHAVIORAL: Family Violence Education Program (FVEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 3 Study of Zandelisib (ME-401) in Combination With Rituximab in Patients With iNHL - (COASTAL)
Status: TERMINATED
Conditions: Follicular Lymphoma (FL)|Non Hodgkin Lymphoma|Marginal Zone Lymphoma
Interventions: DRUG: Zandelisib|DRUG: Rituximab|DRUG: Bendamustine|DRUG: CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Two Patterns of Controlled Ovarian Hyperstimulation in Mid Follicular Phase or Early Luteal Phase for Egg Donors
Status: COMPLETED
Conditions: Stimulation in the Ovary
Interventions: PROCEDURE: Early luteal phase|PROCEDURE: Late follicular phase -COH-
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Mirror Therapy in Patients With Amputations of Lower Limbs of Vascular Origin
Status: COMPLETED
Conditions: Amputation|Phantom Pain Following Amputation of Lower Limb
Interventions: PROCEDURE: Mirror Therapy|DRUG: Gabapentin|PROCEDURE: Rehabilitation|OTHER: Local care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Short-course Radiation Combined With Adebrelimab and CAPEOX Neo-adjuvant Therapy for Organ-retention in Patients With MSS/pMMR Ultra Low Rectal Adenocarcinoma
Status: RECRUITING
Conditions: Rectal Adenocarcinoma
Interventions: DRUG: Adebrelimab|DRUG: Oxaliplatin|DRUG: Capecitabine|RADIATION: Short-course Radiation|PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incobotulinum Toxin for the Treatment of Trigeminal Neuralgia
Status: TERMINATED
Conditions: Trigeminal Neuralgia
Interventions: BIOLOGICAL: Incobotulinumtoxina|OTHER: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Ascending Dose Study of KW-2449 in Acute Leukemias, Myelodysplastic Syndromes, and Chronic Myelogenous Leukemia
Status: TERMINATED
Conditions: Acute Myelogenous Leukemia|Acute Lymphoblastic Leukemia|Myelodysplastic Syndromes|Chronic Myelogenous Leukemia
Interventions: DRUG: KW-2449
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Birth Control Pill vs Birth Control Patch Study
Status: COMPLETED
Conditions: Venous Thrombosis
Interventions: DRUG: Ethinyl estradiol and norgestimate|DRUG: Ethinyl estradiol and norelgestromin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Modeling of Intracerebral Vascularization After Extracorporeal Membrane Oxygenation in Children
Status: RECRUITING
Conditions: Extra Corporeal Membrane Oxygenation|Decanulated Alive
Interventions: OTHER: Magnetic Resonance Angiography (MRA) additional acquisition time|OTHER: Modeling cerebral vascularization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Demonstrate the Superior Efficacy of NYC 0462 Ointment Over That of the Placebo in the Treatment of Plaque Psoriasis
Status: WITHDRAWN
Conditions: Plaque Psoriasis
Interventions: DRUG: NYC 0462 Ointment|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Image-Guided Navigation During Breast Reconstruction in Patients With Breast Cancer
Status: WITHDRAWN
Conditions: Ductal Breast Carcinoma in Situ|Lobular Breast Carcinoma in Situ|Recurrent Breast Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer
Interventions: PROCEDURE: breast reconstruction|PROCEDURE: intraoperative imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Safety, Tolerability and Efficacy of Gene Therapy Drug for Late Onset Pompe Disease (LOPD)
Status: NOT_YET_RECRUITING
Conditions: Pompe Disease (Late-onset)
Interventions: GENETIC: CRG003 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Aloe Vera Toothpaste on Periodontal Parameters
Status: COMPLETED
Conditions: Gingivitis
Interventions: OTHER: Foramen Herbal Aloe toothpaste|OTHER: fluoride toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Tislelizumab Combined With Chemotherapy in the Treatment of Bone Metastases of Unknown Primary
Status: RECRUITING
Conditions: Cancer of Unknown Primary|Bone Cancer Metastatic|Tislelizumab|Gene Mutation-Related Cancer|Immune Evasion, Tumor|Chemotherapy Effect
Interventions: DRUG: Tislelizumab plus chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study to Evaluate Antimicrobial Effectiveness of ZuraPrep™
Status: TERMINATED
Conditions: Surgical Site Infection
Interventions: DRUG: Chloraprep|DRUG: ZuraPrep|DRUG: ZuraPrep Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Comparison of the Modified and Conventional Approach of Radial Artery Cannulation Under Short-axis Ultrasound Guidance in ICU Hypotensive Patients.
Status: UNKNOWN
Conditions: Radial Artery Catheterization
Interventions: PROCEDURE: The modified approach|PROCEDURE: The conventional approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Kinematic and Neuromuscular Deficiencies Phenotypes Associated With Patellofemoral Pain Syndrome
Status: RECRUITING
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: EOS Radiation|BEHAVIORAL: Semi-structured interview
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Open-Label Study of E7974 Administered on Days 1, 8, and 15 of a 28-Day Cycle and Days 1 and 8 of a 21-Day Cycle in Patients With Solid Malignancies
Status: COMPLETED
Conditions: Solid Tumor Malignancies, Cancer
Interventions: DRUG: E7974|DRUG: E7974
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Octreotide Long Acting Release (LAR) in Treatment Naïve Acromegalic Patients
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: Octreotide LAR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional MRI (fMRI) in CGRP Induced Migraine
Status: COMPLETED
Conditions: Migraine Without Aura
Interventions: DRUG: infusion of calcitonin gene related peptide (CGRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Nasal Irrigation With Chinese Herbal Medicine as an Adjunctive Treatment in Allergic Rhinitis
Status: COMPLETED
Conditions: Rhinitis, Allergic|Nasal Lavage|Medicine, Chinese Traditional
Interventions: DRUG: Szechwan Lovage Rhizome, Biod Magnolia Bud, Taiwan Angelica Root, Wild Mint Herb, Baikal Skullcap Root, and Borneol|DRUG: edible caramel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: F&P Toffee Full Face Mask Clinical Trial, NZ, 2020
Status: COMPLETED
Conditions: Positive Airway Pressure Therapy|Obstructive Sleep Apnea
Interventions: DEVICE: Toffee Full Face Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pegcetacoplan (APL-2) Therapy in Patients With Geographic Atrophy
Status: COMPLETED
Conditions: Geographic Atrophy
Interventions: DRUG: Pegcetacoplan|OTHER: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oxygen for Vascular Incisional Healing
Status: UNKNOWN
Conditions: Surgical Wound Healing|Lower Extremity|Revascularization|Incision
Interventions: DEVICE: EPIFLO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radicle Health1: A Study of Health and Wellness Formulations and Their Effects on Overall Health
Status: COMPLETED
Conditions: Sleep|Pain|Depression|Anxiety
Interventions: DIETARY_SUPPLEMENT: Placebo Control Form 1 Capsules|DIETARY_SUPPLEMENT: Health Active Study Product 1.1 Capsules|DIETARY_SUPPLEMENT: Health Active Study Product 1.2 Capsules|DIETARY_SUPPLEMENT: Health Active Study Product 1.3 Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effects of Health Education for Patients Received Minimally Invasive Lumbar Spinal Surgery
Status: UNKNOWN
Conditions: Low Back Pain|Lumbar Degenerative Disease
Interventions: BEHAVIORAL: Perioperative Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of RAS on Gait in PD Patients With DBS
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Rhythmic Auditory Stimulation (RAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 1.2% Atorvastatin and 1.2% Simvastatin in Treatment of Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: 1.2% Atorvastatin local drug delivery|DRUG: 1.2% simvastatin local drug delivery|DRUG: Placebo local drug delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Drug Eluting Stent and Covered Metal Stent in Malignant Biliary Obstruction (MIRA III)
Status: COMPLETED
Conditions: Biliary Neoplasms|Biliary Obstruction|Pancreatic Neoplasms
Interventions: DEVICE: Paclitaxel-eluting metal Stent|DEVICE: Covered Metal Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: HAIC Sequential TAE Combined With Tislelizumab and Surufatinib in Unresectable Intrahepatic Cholangiocarcinoma
Status: RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: HAIC+TAE|DRUG: Tislelizumab|DRUG: Surufatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Peer-Supported Psychosocial Skills Training in Individuals With Chronic Mental Disorder
Status: COMPLETED
Conditions: Chronic Mental Disorders|Peer Support|Psychosocial Skills Training|Functionality|Stigmatization|Insight
Interventions: OTHER: Peer practitioner training - Peer Education Supported Psychosocial Skills Education|OTHER: Peer Education Supported Psychosocial Skills Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A One-year Randomized Controlled Trial Evaluating the Impact of Pioglitazone Versus Linagliptin on Bone Turnover Markers
Status: UNKNOWN
Conditions: Osteoporosis|Diabetes Mellitus
Interventions: DRUG: Pioglitazone|DRUG: Linagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Low Voltage Pulsed Electromagnetic Fields (T-PEMF) in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: Transcranial low voltage pulsed electromagnetic fields (T-PEMF)|DEVICE: Placebo Transcranial low voltage electromagnetic fields
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Embolization of the Middle Meningeal Artery With ONYX™ Liquid Embolic System for Subacute and Chronic Subdural Hematoma
Status: RECRUITING
Conditions: Subdural Hematoma
Interventions: PROCEDURE: Surgical Management|DEVICE: Surgical Management + Treatment|OTHER: No Treatment|DEVICE: Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Imaging Analysis During Treatment With Bevacizumab in Patients With Recurrent Glioblastoma
Status: TERMINATED
Conditions: Glioblastoma
Interventions: DRUG: F-MISO|OTHER: Cerebral magnetic resonance imagery|DRUG: Bevacizumab|OTHER: Clinical examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of TAP Block on Time Required for First Analgesic Dose After Cesarean Cection Under Spinal Anesthesia
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Transversus abdominus plane block|DRUG: Transversus abdominus plane placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial to Evaluate Safety and Efficacy of Rivaroxaban (COVID-19)
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: Rivaroxaban|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-MD1003 in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: [14C]-MD1003
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Tolvaptan add-on Therapy to Overcome Loop Diuretic Resistance in Acute Heart Failure With Renal Dysfunction
Status: UNKNOWN
Conditions: Acute Heart Failure
Interventions: DRUG: Tolvaptan 15 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Vitamin D on Beta Cell Function and Insulin Sensitivity in Pre-diabetes and Diabetes Mellitus Type 2
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Glucose Intolerance|Vitamin D Deficiency
Interventions: DRUG: Vitamin D3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Chronic Hypnotic Use 2
Status: COMPLETED
Conditions: Chronic Insomnia
Interventions: DRUG: placebo|DRUG: Zolpidem CR|DRUG: Eszopiclone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Growth and Tolerance of Infants Fed Milk-Based Infant Formula
Status: COMPLETED
Conditions: Gastro-Intestinal Tolerance
Interventions: OTHER: Control Infant Formula|OTHER: Experimental Infant Formula|OTHER: Reference Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Paediatric Chronic Tracheostomy Care: An Evaluation of an Innovative Competency-based Education Program for Community Health Care Providers
Status: COMPLETED
Conditions: Evaluation of HomeCare RN Respiratory Education
Interventions: OTHER: Tracheostomy Training Course
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Characterization of BAM8-22 as a New Surrogate Model of Non-histaminergic Itch
Status: COMPLETED
Conditions: Itch
Interventions: DRUG: BAM8-22|DRUG: Histamine|DRUG: Cowhage (Mucuna Pruriens)|DRUG: Doxepin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clopidogrel Reloading in Clopidogrel Resistant Patients With ACS
Status: COMPLETED
Conditions: Clopidogrel Non-Responsiveness
Interventions: DRUG: clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Apathy in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DEVICE: High-Frequency Repetitive Transcranial Magnetic Stimulation|DEVICE: Sham Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Resveratrol to Prevent Post-ERCP Pancreatitis
Status: UNKNOWN
Conditions: Pancreatitis, Acute|Gastrointestinal Disease
Interventions: DRUG: Resveratrol|DRUG: Indomethacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Tosylate in Treating Patients With Malignant Mesothelioma.
Status: COMPLETED
Conditions: Epithelial Mesothelioma|Recurrent Malignant Mesothelioma|Sarcomatous Mesothelioma|Stage IA Malignant Mesothelioma|Stage IB Malignant Mesothelioma|Stage II Malignant Mesothelioma|Stage III Malignant Mesothelioma|Stage IV Malignant Mesothelioma
Interventions: DRUG: sorafenib tosylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Norepinephrine to Prevent Hypotension in Ceasrean Delivery
Status: COMPLETED
Conditions: Hypotension|Cesarean Section Complications
Interventions: DRUG: Norepinephrine bolus|DEVICE: cardiometry|DRUG: Norepinephrine infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Platelet Activation by Severe Aortic Stenosis and Its Correction by Transcatheter Aortic Valve Implantation
Status: COMPLETED
Conditions: Aortic Stenosis
Interventions: OTHER: test|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intranasal Insulin for Treatment of Alcohol Use Disorder
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: Regular Human Insulin then Placebo|DRUG: Placebo then Regular Human Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nonopioid Analgesia After Anterior Cruciate Ligament Reconstruction
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Injury
Interventions: DRUG: Celecoxib|DRUG: Hydrocodone-Acetaminophen|DRUG: Ketorolac|DRUG: Gabapentin|DRUG: Acetaminophen|DRUG: Diazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT