pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Investigating the Effect of Interval Walking and Qigong on People With Knee Osteoarthritis: Pilot Study
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: BEHAVIORAL: Interval walking and Qigong exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Hemodialysis With Hemoperfusion：A Clinical Study
Status: COMPLETED
Conditions: Renal Dialysis|Hemoperfusion|Quality of Life
Interventions: DEVICE: hemoperfusion apparatus|DEVICE: low flux dialyzer|DEVICE: high flux dialyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Two Doses of 2',3'-Dideoxycytidine (ddC) in the Treatment of Children With Symptomatic HIV Infection Who Are Intolerant of AZT and/or Who Show Progressive Disease While on AZT
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zalcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Intermittent Levetricetam in Treatment of Febrile Convulsions
Status: NOT_YET_RECRUITING
Conditions: Febrile Convulsion
Interventions: DRUG: Levetiracetam|DRUG: Diazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effect of Different Concentrations of SPARC1102 on Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: SPARC1102 I|DRUG: SPARC1102 II|DRUG: SPARC1102 III|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bridge Occlusion Balloon in Lead Extraction Procedure
Status: COMPLETED
Conditions: C.Surgical Procedure; Cardiac|Cardiac Dysrhythmia|Disorder of Pacing Function
Interventions: DEVICE: Bridge Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: (Summit) A Study to Evaluate the Efficacy and Safety of CGT9486 Versus Placebo in Patients With Indolent or Smoldering Systemic Mastocytosis
Status: RECRUITING
Conditions: SSM|Mastocytosis, Indolent|Mastocytosis, Systemic|Mastocytosis
Interventions: DRUG: Bezuclastinib Tablets (Formulation A)|DRUG: Bezuclastinib Tablets (Formulation B)|DRUG: Placebo Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SCREENING FOR THE IMPLANTATION OF A SUBCUTANEOUS IMPLANTABLE AUTOMATIC DEFIBRILLATOR
Status: COMPLETED
Conditions: Sudden Cardiac Death|Implantable Defibrillator
Interventions: PROCEDURE: new screening procedure with small variations in electrode positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bergen Oral Respiratory Intervention Study
Status: ENROLLING_BY_INVITATION
Conditions: Periodontitis|Airway Obstruction|Lung Inflammation
Interventions: PROCEDURE: Periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Hope Placement Program on Dıagnosed Wıth MS
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: psychotherapeutic intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of Once Daily Topical Treatment With LEO 90100 Aerosol Foam in Adolescent Subjects With Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: LEO 90100
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of the Safety and Efficacy of FG-2216 in Subjects With Renal Anemia Not Requiring Dialysis and Not Receiving Recombinant Human Erythropoietin
Status: COMPLETED
Conditions: Renal Anemia
Interventions: DRUG: FG2216
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Vorinostat and Gemtuzumab Ozogamicin in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: gemtuzumab ozogamicin|DRUG: vorinostat|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Uralyt-U in Patients With Hyperuricemia
Status: UNKNOWN
Conditions: Uric Acid Stones|Hyperuricemia
Interventions: DRUG: Febuxostat|DRUG: Uralyt-U
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Two Methods of Expanding Stents Placed in Legs of Diabetics With Peripheral Vascular Disease
Status: COMPLETED
Conditions: PERIPHERAL VASCULAR DISEASE
Interventions: PROCEDURE: Conventional angioplasty balloon|PROCEDURE: cryoplasty balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects Of High Intensity Interval Training On Speed And Explosive Strength In Sprinters
Status: COMPLETED
Conditions: Sprinters
Interventions: OTHER: EFFECTS OF HIGH INTENSITY INTERVAL TRAINING IN SPRINTERS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Outcomes of Preoperative and Postoperative Rehabilitation in the Patients With HBP Malignancy
Status: COMPLETED
Conditions: Hepatic Neoplasms|Biliary Tract Neoplasms|Pancreatic Neoplasms
Interventions: BEHAVIORAL: Perioperative rehabilitation program|BEHAVIORAL: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pre-operative 5-Fluorouracil (5-FU) and Sorafenib With External Radiation in Locally Advanced Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DRUG: Sorafenib|DRUG: 5-Fluorouracil (5-FU)|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic BM-MSC's in Patients With Lumbar Facet Arthropathy
Status: RECRUITING
Conditions: Facet-Mediated Low Back Pain
Interventions: DRUG: BM-MSC injection|DRUG: DSMO Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Tolerability of CFT8634 in Locally Advanced or Metastatic SMARCB1-Perturbed Cancers, Including Synovial Sarcoma and SMARCB1-Null Tumors
Status: TERMINATED
Conditions: Synovial Sarcoma|Soft Tissue Sarcoma
Interventions: DRUG: CFT8634
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Exercise in OCD: Treatment Efficacy, Additive Benefits to CBT, and Cognitive Correlates of Change
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder|Cognition Disorders
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Cognitive Behavioural Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Plus Capecitabine (SorCape) in Previously Treated Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Sorafenib Plus Capecitabine (SorCape)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Trial to Evaluate the Efficacy and Safety of CKD-497
Status: COMPLETED
Conditions: Respiratory Infection
Interventions: DRUG: CKD-497 200mg|DRUG: CKD-497 300mg|DRUG: CKD-497 placebo|DRUG: Comparator|DRUG: Comparator placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Neuromodulation of the Prefrontal Cortex in Subjects With Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DEVICE: Active transcranial direct current stimulation (tDCS)|OTHER: Hypocaloric diet|OTHER: Sham transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Hypoalgesic Effects of Transcranial Direct Current (tDCS) in Healthy Subjects
Status: UNKNOWN
Conditions: Pain Modulation
Interventions: DEVICE: Sooma transcranial direct current stimulation device plus Brain training tools|DEVICE: Placebo Sooma transcranial direct current stimulation deviceplus Brain training tools|BEHAVIORAL: Brain training tools in isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Detroit Area Study of College Student Lifestyles
Status: COMPLETED
Conditions: Excessive Alcohol Consumption
Interventions: BEHAVIORAL: BASICS motivational interview|BEHAVIORAL: BASICS plus normative enhancement motivational interview|BEHAVIORAL: Self-directed: Information only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of Spironolactone Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Bioequivalence Study
Interventions: DRUG: Spironolactone Tablets (Test)|DRUG: Spironolactone Tablets (Reference)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ultrasound for Double Lumen Endotracheal Tube
Status: TERMINATED
Conditions: Lung Ultrasound
Interventions: DEVICE: Determination of tube position by ultrasound.|OTHER: Determination of tube position by auscultation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Evaluations and Laboratory Studies to Study the Disease Course in Patients With Cutaneous T-Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: GENETIC: gene rearrangement analysis|GENETIC: polymerase chain reaction|GENETIC: proteomic profiling|OTHER: flow cytometry|OTHER: immunohistochemistry staining method|PROCEDURE: biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Probiotics in Hospitalized Patients Study
Status: WITHDRAWN
Conditions: Antibiotic Associated Diarrhea|Clostridium Difficile Associated Diarrhea
Interventions: DIETARY_SUPPLEMENT: Go Live
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Clinical, Meibographic and Interferometric Evaluation of Phlyctenular Keratitis in Children - MEIBO-ROSACEE
Status: COMPLETED
Conditions: Ocular Rosacea|Keratoconjunctivitis|Meibomian Gland Dysfunction
Interventions: PROCEDURE: Ophthalmologic examination and meibographic and interferometric evaluation (Lipiview device)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Xiidra vs. Xiidra + Dextenza Treatment for Dry Eye Disease
Status: TERMINATED
Conditions: Dry Eye Syndromes
Interventions: DRUG: Lifitegrast 5% Ophthalmic Solution|DRUG: Dexamethasone Intracanalicular Insert, 0.4mg with Lifitegrast 5% Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Nintedanib Combined With Paclitaxel Chemotherapy for Patients With BRAF wt Metastatic Melanoma
Status: COMPLETED
Conditions: Cutaneous Malignant Melanoma
Interventions: DRUG: Nintedanib|DRUG: Nintedanib-Placebo|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study With Quadrivalent Recombinant Influenza Vaccine (RIV4) in Participants 9 Through 49 Years of Age.
Status: COMPLETED
Conditions: Influenza Immunization
Interventions: BIOLOGICAL: Quadrivalent Recombinant influenza vaccine (RIV4) season/2022-2023/NH
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lymphocytic Subsets and Cytokine Production With H. Pylori Infection
Status: COMPLETED
Conditions: Duodenal Ulcer|Gastric Ulcer|Dyspepsia
Interventions: PROCEDURE: immune response
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Exploratory, Phase 0 Study of Positron Emission Tomography (PET) Imaging Agent, F-18 RGD-K5
Status: COMPLETED
Conditions: Sarcoma|Melanoma|Lung Cancer|Breast Cancer|High Grade Gliomas
Interventions: DRUG: F-18 RGD-K5
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Psychiatric Symptoms in Employees Experiencing High Levels of Stress Before and After the Intake of Probiotics
Status: COMPLETED
Conditions: Probiotics
Interventions: DIETARY_SUPPLEMENT: PS128|DIETARY_SUPPLEMENT: PS23 live|DIETARY_SUPPLEMENT: PS23 heat-treated|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Panitumumab and Irinotecan for Malignant Gliomas
Status: TERMINATED
Conditions: Malignant Glioma of Brain
Interventions: DRUG: Irinotecan|DRUG: Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccination-Dendritic Cells With Peptides for Recurrent Malignant Gliomas
Status: COMPLETED
Conditions: Malignant Glioma
Interventions: BIOLOGICAL: Dendritic vaccine pulsed with multiple peptides|BIOLOGICAL: The first booster vaccine phase:|BIOLOGICAL: The second booster vaccine phase:
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lopinavir/Ritonavir in Combination With Saquinavir Mesylate or Lamivudine/Zidovudine to Explore Metabolic Toxicities in Antiretroviral HIV-Infected Subjects
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lopinavir/ritonavir|DRUG: Saquinavir mesylate|DRUG: Lamivudine/zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplant (FMT) in Pediatric Active Ulcerative Colitis and Pediatric Active Crohn's Colitis
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Ulcerative Colitis|Crohn Disease
Interventions: BIOLOGICAL: Fecal Microbiota Transplant (FMT)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Inspiratory Muscle Training in Patient With Stable Angina
Status: COMPLETED
Conditions: Angina, Stable
Interventions: DEVICE: Inspiratory muscle training with PowerBreathe (IMT Technologies Ltd., Birmingham,England)|DEVICE: Sham group with PowerBreathe (IMT Technologies Ltd., Birmingham, England)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Cholestyramine and Prednisolone as Adjunctive Therapy in Treatment of Overt Hyperthyroidism
Status: UNKNOWN
Conditions: Hyperthyroidism|Graves Disease
Interventions: DRUG: Cholestyramine Powder 4g|DRUG: Prednisolone|DRUG: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebral Blood Flow: Helmet vs Oronasal Mask During Continuous Positive Airway Pressure Ventilation
Status: NOT_YET_RECRUITING
Conditions: Ventilation Therapy
Interventions: DEVICE: Helmet Continuous Positive Airway Pressure|DEVICE: Oronasal Mask Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Acid Base Status During High Salt Intake
Status: COMPLETED
Conditions: Low Grade Metabolic Acidosis
Interventions: DIETARY_SUPPLEMENT: High NaCl + KHCO3|OTHER: Control: high NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hypo-mineralization of Primary and Permanent Teeth in a Group of Children With Stunted Growth.A Cross Sectional Study.
Status: UNKNOWN
Conditions: Short Stature|Hypomineralization Molar Incisor|Hypomineralization of Enamel
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cannabidiol to Reduce Anxiety Reactivity
Status: COMPLETED
Conditions: Social Anxiety|Social Anxiety Disorder
Interventions: DRUG: Cannabidiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Pirfenidone in Patient With Systemic Sclerosis-associated Interstitial Lung Disease
Status: UNKNOWN
Conditions: Systemic Sclerosis-associated Interstitial Lung Disease (Ssc-ild)
Interventions: DRUG: Pirfenidone|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Intravenous Lactated Ringer Solution Raise Measured Serum Lactate?
Status: COMPLETED
Conditions: Hyperlactatemia
Interventions: DRUG: Lactated Ringer Solution|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Anterior Tibial Knee Translation in Healthy Women With and Without Hormone Therapy
Status: NOT_YET_RECRUITING
Conditions: Women|Tibial Translation|Hormone
Interventions: OTHER: Questionnaire|OTHER: Beighton test|OTHER: Lachman Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Positron Emission Tomography (PET) Study to Evaluate Biodistribution of [11C]-GSK2256098 in Healthy Subjects and Idiopathic Pulmonary Arterial Hypertension (PAH) Patients
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: [11C]-GSK2256098 500 MBq
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Hemodynamic Effects of SGLT2i in Acute Decompensated Heart Failure
Status: TERMINATED
Conditions: Acute Decompensated Heart Failure
Interventions: DRUG: SGLT2i|OTHER: No SGLT2i
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension to Study MA21573, Evaluating Tocilizumab in Patients With Active Rheumatoid Arthritis and an Inadequate Response to Current Non-Biological DMARDs and/or Anti-tumor Necrosis Factor (TNF) Therapy
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab [RoActemra/Actemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Discomfort After Dental General Anesthesia
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DEVICE: Laryngeal mask airway|DEVICE: Nasotracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Resistance Training in Patients With Morbid Obesity
Status: COMPLETED
Conditions: Morbid Obesity|Obesity|Physical Activity|Metabolic Syndrome|Risk Factor, Cardiovascular
Interventions: OTHER: Behavioral
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Peppermint Oil as a Treatment for Children With Bladder and Bowel Dysfunction
Status: ENROLLING_BY_INVITATION
Conditions: Bladder and Bowel Dysfunction
Interventions: DIETARY_SUPPLEMENT: Peppermint Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine and Melatonin for Sleep Induction for EEG in Children
Status: COMPLETED
Conditions: Electroencephalography|Child|Dexmedetomidine|Melatonin|Sleep|Epilepsy
Interventions: DIAGNOSTIC_TEST: Electroencephalography|DIAGNOSTIC_TEST: Monitoring of vital functions|DRUG: Melatonin 0,1mg/kg oral syrup|DRUG: Dexmedetomidine 3 mcg/kg sublingually|DRUG: Dexmedetomidine 3 mcg/kg intranasally
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Multi-center, Randomized, Double-blind, Parallel-group, Placebo Controlled Phase III Study to Evaluate the Efficacy and Safety of LXI-15028 in Non-erosive Reflux Disease in Chinese Patients for 4 Weeks
Status: COMPLETED
Conditions: Non-erosive Reflux Disease
Interventions: DRUG: LXI-15028|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Monocentric Study to Assess the Concordance of Lung MRI Compared to Chest CT Scan to Assess the Extent and Severity of Bronchial and Parenchymal Pulmonary Lesions in Adult Patients With Primary Immune Deficiency (PID) .
Status: UNKNOWN
Conditions: Primary Immune Deficiency
Interventions: OTHER: MRI procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors
Status: RECRUITING
Conditions: Colorectal Cancer Not MSI-H or MMR-deficient|GIST|Oesophageal or Gastric Carcinoma|Biliary Tract Cancer|Hepatocellular Carcinoma|Soft-tissue Sarcoma|Thyroid Cancer|Gastro-enteropancreatic Neuroendocrine Tumor|Non-small Cell Lung Cancer|Solid Tumor, Adult|Urothelial Carcinoma|HPV-Related Carcinoma|Triple Negative Breast Cancer|Renal Carcinoma|Mesotheliomas Pleural
Interventions: DRUG: Phase 1 : Regorafenib|DRUG: Phase 1 : Avelumab|DRUG: Phase 2 : Regorafenib|DRUG: Phase 2 : Avelumab|DRUG: Phase 2: low-dose Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contrast Enhanced Sonothrombolysis and Sonolysis in Stroke - a Swedish Study (CE-5S)
Status: TERMINATED
Conditions: Ischemic Stroke
Interventions: DRUG: SonoVue|DRUG: Sodium chloride|PROCEDURE: Transcranial Ultrasound|PROCEDURE: Sham Transcranial Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Long-term Clinical Safety and Efficacy of Subcutaneously Administered C1-esterase Inhibitor in the Prevention of Hereditary Angioedema
Status: COMPLETED
Conditions: Hereditary Angioedema Types I and II
Interventions: BIOLOGICAL: C1-esterase inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Separate and Combined Extrapancreatic Effects of the Incretin Hormones
Status: COMPLETED
Conditions: Pancreatectomy; Hyperglycemia
Interventions: OTHER: Intravenous infusion|OTHER: Intravenous infusion|OTHER: Intravenous infusion|OTHER: Intravenous infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cell Therapy for Craniofacial Bone Defects
Status: COMPLETED
Conditions: Cleft Palate|Trauma
Interventions: BIOLOGICAL: Ixmyelocel-T|PROCEDURE: Autogenous Bone Grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EXCLAIM:Extended Prophylaxis for Venous ThromboEmbolism (VTE) in Acutely Ill Medical Patients With Prolonged Immobilization
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: enoxaparin sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Prevalence of Human Papillomavirus in Barrett Esophagus Compared With Controls
Status: COMPLETED
Conditions: Barrett Esophagus
Interventions: PROCEDURE: esophagus biopsies (pathologic and healthy zones)|PROCEDURE: esophagus biopsies (healthy zones)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Imaging Whole Coronary Artery With Intravascular Ultrasound (Ivus) And Imap For Plaque Tissue Composition In Patients With Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DEVICE: iMAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Low or High Ligation of the IMA With Apical Lymph Node Dissection in Rectal Cancer Laparoscopic Surgery
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: PROCEDURE: Low ligation with apical lymph node dissection|PROCEDURE: High ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Department of Defense PTSD Adaptive Platform Trial Intervention A - Fluoxetine
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder
Interventions: DRUG: Intervention A Fluoxetine Hydrochloride (HCl)|DRUG: Intervention A Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study With Two Different Doses of Desmopressin Orally Lyophilisate Tablet With Nocturnal Enuresis
Status: COMPLETED
Conditions: Nocturnal Enuresis
Interventions: DRUG: Desmopressin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Mitomycin C-based HIPEC After srHCC and PM of HCC
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Peritoneal Metastasis|Hyperthymic|HCC
Interventions: PROCEDURE: mitomycin C-based hyperthermic intraperitoneal chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Feasibility of a Multimodal Intervention Program to Optimize Treatment Outcomes in Ulcerative Colitis
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis
Interventions: BEHAVIORAL: Multimodal intervention program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase II Clinical Trial for Inactivated Vaccine (Vero Cell) Against EV71 in Chinese Children and Infants
Status: COMPLETED
Conditions: Immunogenicity|Safety
Interventions: BIOLOGICAL: 160U /0.5ml EV71 Vaccine|BIOLOGICAL: 320U /0.5ml EV71 vaccine|BIOLOGICAL: 640U /0.5ml EV71 vaccine|BIOLOGICAL: (without adjuvant) 640U /0.5ml|BIOLOGICAL: 0/0.5ml placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy Safety Study Comparing 2 Doses of NVP After Initiating Rifampin-containing TB Therapy
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: HAART containing nevirapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of DTaP-IPV-Hep B-PRP~T Combined Vaccine Compared to Infanrix®Hexa in Healthy Peruvian Infants
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Haemophilus Influenzae Type b|Hepatitis B
Interventions: BIOLOGICAL: DTaP IPV HB PRP~T vaccine|BIOLOGICAL: DTaP-HB-IPV and Haemophilus influenzae type b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the SONAS® Ultrasound Device for the Assessment of Bilateral Cerebral Perfusion in Subjects With Acute Stroke
Status: UNKNOWN
Conditions: Stroke, Acute
Interventions: DEVICE: SONAS® Ultrasound Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Paclitaxel or S1 Plus Cisplatin in Concurrent Chemoradiotherapy for Squamous Cell Carcinoma of Esophagus
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: OTHER: Paclitaxel plus Cisplatin with radiotherapy|OTHER: S1 plus Cisplatin with radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Protocol for Multiple Sclerosis Patients Who Participated in Genzyme-Sponsored Studies of Alemtuzumab
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: BIOLOGICAL: alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Low-Dose Isotretenion and Long-Pulsed 1064 ND-YAG Laser in the Treatment of Acne Erythema
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: COMBINATION_PRODUCT: Combined Low-Dose Isotretenion and Long-Pulsed 1064 ND-YAG Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Centanafadine Efficacy, Safety, and Tolerability in Adult Subjects With Binge Eating Disorder
Status: COMPLETED
Conditions: Binge-Eating Disorder
Interventions: DRUG: Centanafadine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PEMF Therapy to Treat Lingering Symptoms of Lyme Disease After Treatment With Antibiotics
Status: TERMINATED
Conditions: Lyme Disease|Lyme Neuroborreliosis|Lyme Arthritis|Unknown Origin Fever
Interventions: DEVICE: Scientific Consciousness Interface Operations (SCIO) Class II FDA approved medical device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of IDN-6556 in Post Orthotopic Liver Transplant for Chronic HCV
Status: COMPLETED
Conditions: Liver Fibrosis|Hepatic Fibrosis|Liver Cirrhosis|Hepatic Cirrhosis
Interventions: DRUG: IDN-6556|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess Safety and Efficacy of Myoblast Implantation Into Myocardium Post Myocardial Infarction
Status: UNKNOWN
Conditions: Congestive Heart Failure
Interventions: BIOLOGICAL: MyoCell|BIOLOGICAL: MyoCell|PROCEDURE: Hypothermosol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: QM-B and QM-C Hysterectomy for Early Cervical Cancer
Status: RECRUITING
Conditions: Uterine Cervical Neoplasms
Interventions: PROCEDURE: QM-C Hysterectomy|PROCEDURE: QM-B Hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Intra-coronary Nitrite in Acute Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction|Reperfusion Injury|Myocardial Ischemia|Cardiovascular Diseases
Interventions: DRUG: Sodium Nitrite|DRUG: Sodium Chloride Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 12 Week, Phase II Trial to Evaluate the Efficacy and Safety of WIN-34B in Patients With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: WIN-34B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Game-based Neurodevelopmental Assessment for Young Children
Status: RECRUITING
Conditions: Neurodevelopmental Disorders|Autism Spectrum Disorder|Attention Deficit Hyperactivity Disorder|Dyslexia|Specific Learning Disorder|Child Development
Interventions: DIAGNOSTIC_TEST: Tablet Game-based Assessment - YARN assessment service|DIAGNOSTIC_TEST: Adaptive Behavior Assessment System, Third Edition (ABAS-3)|OTHER: Demographic questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Milnacipran in the Treatment of Widespread, Non-Joint Pain in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Milnacipran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intermediate Cleft Rhinoplasty in Unilateral Cleft Lip Patients: Approaches and Outcomes
Status: RECRUITING
Conditions: Unilateral Cleft Lip
Interventions: PROCEDURE: intermediate cleft rhinoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Erlotinib After Completing Chemoradiotherapy in Locally Advanced Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: erlotinib hydrochloride|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effects of Dexpramipexole in Participants With Eosinophilic COPD
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Dexpramipexole Dihydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Intra-hepatic Administration of Therasphere® in Association With Intravenous Chemotherapy to Treat Cholangiocarcinoma
Status: COMPLETED
Conditions: Cholangiocarcinoma
Interventions: RADIATION: Therasphere® in association with Gemcitabine and Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antineoplaston Therapy in Treating Patients With Stage IV Adrenal Gland Cancer
Status: TERMINATED
Conditions: Stage IV Adrenocortical Carcinoma
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DEFINE - Evaluating Therapies for COVID-19
Status: RECRUITING
Conditions: COVID-19
Interventions: DRUG: Nafamostat Mesilate|DRUG: TD139|OTHER: Standard care|BIOLOGICAL: Allogeneic SARS-CoV-2 VSTs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Sports Supplements on Blood Flow
Status: COMPLETED
Conditions: Determine the Effects of Nitrosigine and Citrulline-malate on Flow-mediated Dilation Among Young Adults
Interventions: DIETARY_SUPPLEMENT: inositol-stabilized arginine silicate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Efficacy of Adjunctive Use of Ondansetron in Patients With Sepsis and Septic Shock
Status: RECRUITING
Conditions: Sepsis|Septic Shock
Interventions: DRUG: Ondansetron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BDPP Treatment for Mild Cognitive Impairment (MCI) and Prediabetes or Type 2 Diabetes Mellitus (T2DM)
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Alzheimer's Disease
Interventions: DRUG: grape seed polyphenolic extract, resveratrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing 61.2 Gy Radiotherapy Dose Versus 50.4 Gy Radiotherapy Dose for Locally Advanced Esophageal Carcinoma
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Biofeedback in Improving Continence After Anterior Resection
Status: COMPLETED
Conditions: Rectal Neoplasms|Fecal Incontinence|Aged
Interventions: BEHAVIORAL: Biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Effectiveness and Safety of Diluted RADIESSE® in the Treatment of Décolleté Wrinkles
Status: COMPLETED
Conditions: Décolleté Wrinkles
Interventions: DEVICE: Treatment with diluted Radiesse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Signatures of N-Ac for Non-Suicidal Self-Injury in Adolescents
Status: COMPLETED
Conditions: Self-Harm|Depression|Suicide
Interventions: DRUG: N-acetyl cysteine|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Volume Controlled Ventilation With 1:1 Inspiratory to Expiratory Ratio and Autoflow-volume Controlled Ventilation in Robot-assisted Laparoscopic Radical Prostatectomy With Steep Trendelenburg Position and Pneumoperitoneum
Status: COMPLETED
Conditions: Robot Assisted Laparoscopic Prostatectomy
Interventions: PROCEDURE: ventilation strategy 1|PROCEDURE: ventilation strategy 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ContriBution of Digital RemOte MoniToring to IMPROVing The Effectiveness of Treatment in Patients With Chronic Heart Failure With Low Ejection Fraction
Status: RECRUITING
Conditions: Chronic Heart Failure With Low Ejection Fraction
Interventions: DEVICE: Telebot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Establish the uSI Values and End-user Training Material That Will be Used to Guide Oxytocin Dosing Actions
Status: UNKNOWN
Conditions: Pregnancy Related|Labor Long|Fetal Distress
Interventions: DEVICE: uterine electromyography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of Splanchnic Vein Thrombosis With Rivaroxaban. A Pilot, Prospective Cohort Study
Status: UNKNOWN
Conditions: Portal Vein Thrombosis|Mesenteric Vein Thrombosis|Splenic Vein Thrombosis
Interventions: DRUG: rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Evaluation of a Portable Wedge Device for Calf Stretching to Alleviate Strain and Spasms
Status: ACTIVE_NOT_RECRUITING
Conditions: Spasm
Interventions: DIAGNOSTIC_TEST: Deep Friction massage|COMBINATION_PRODUCT: Therapeutic exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: High-Dose Melphalan Plus Peripheral Stem Cell Transplantation in Treating Patients With Primary Systemic Amyloidosis
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: filgrastim|DRUG: melphalan|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Pelvic Hypofractionated Radiotherapy in Endometrial Cancer
Status: RECRUITING
Conditions: Endometrial Cancer
Interventions: RADIATION: Hypofractionated Radiation|OTHER: Clinical Follow-Up and Assessments
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine and Sufentanil Effect in PCA on Pediatric Patients Undergoing Scoliosis Surgery
Status: UNKNOWN
Conditions: Dexmedetomidine
Interventions: DRUG: low dose of dexmedetomidine with sufentanil|DRUG: high dose of dexmedetomidine with sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Study of PLM60 for the Treatment of Cutaneous T Cell Lymphomas
Status: TERMINATED
Conditions: Relapsed Cutaneous T Cell Lymphom
Interventions: DRUG: Mitoxantrone HCL Liposome Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of TNX-832 (Sunol cH36) in Subjects With Acute Lung Injury/Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Sepsis|Acute Lung Injury|Acute Respiratory Distress Syndrome
Interventions: BIOLOGICAL: TNX-832|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PXD101 in Treating Patients With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma
Interventions: DRUG: belinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccination With Dendritic Cell/Tumor Fusions With Autologous Stem Cell Transplants in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: Dendritic Cell Tumor Fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Analgesia With Lidocaine or Extended-release Oxycodone for Neuropathic Pain Treatment in Multiple Sclerosis
Status: TERMINATED
Conditions: Neuropathic Pain|Chronic Pain|Multiple Sclerosis
Interventions: DRUG: Lidocaine patch 5%|DRUG: Extended-release oxycodone|DRUG: Placebo extended-release oxycodone pills|DRUG: Placebo lidocaine patches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Technology-augmented Self-monitoring Model Among Patients With Type 2 Diabetes and Hypertension
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Hypertension
Interventions: DEVICE: Technology-based self-management model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Efficacy and Safety of KH001 in Patients With Dentin Hypersensitivity
Status: RECRUITING
Conditions: Dentin Hypersensitivity
Interventions: DRUG: KH001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Zinc Supplementation to Improve Prognosis in Patients With Compensated Advanced Chronic Liver Disease.
Status: RECRUITING
Conditions: Advanced Chronic Liver Disease|Portal Hypertension|Hepatocellular Carcinoma
Interventions: DRUG: Zinc Acexamate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT