pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of the Purified Vero Rabies Vaccine - Serum Free in Comparison With the Reference Purified Vero Rabies Vaccine
Status: COMPLETED
Conditions: Rabies|Rabies Virus
Interventions: BIOLOGICAL: Purified inactivated rabies vaccine, serum free|BIOLOGICAL: Purified inactivated rabies vaccine, serum free|BIOLOGICAL: Purified Vero Rabies Vaccine|BIOLOGICAL: Purified Vero Rabies Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Gamification-Augmented Home-Based Exercise for Peripheral Artery Disease
Status: COMPLETED
Conditions: Peripheral Artery Disease
Interventions: BEHAVIORAL: Gamification and Social Incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Evaluation of a 1-Piece Intraocular Lens
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Tecnis ZCB00 IOL (control)|DEVICE: Toric Intraocular lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Cerebral Monitoring on Neurologic Outcome in Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Surgical Procedures
Interventions: PROCEDURE: If any intraoperative EEG abnormality and/or asymmetry is detected a cerebral CT scan will be performed in the immediate postoperative period
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Medico-economic Evaluation of the Therapeutic Drug Monitoring of Anti-TNF-α Agents in Inflammatory Bowel Diseases
Status: COMPLETED
Conditions: Crohn's Disease|Ulcerative Colitis
Interventions: OTHER: Immuno monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Testing the Combination of Pevonedistat With Chemotherapy for Bile Duct Cancer of the Liver
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Cholangiocarcinoma|Metastatic Hepatocellular Carcinoma|Stage III Hepatocellular Carcinoma AJCC v8|Stage III Intrahepatic Cholangiocarcinoma AJCC v8|Stage IIIA Hepatocellular Carcinoma AJCC v8|Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8|Stage IIIB Hepatocellular Carcinoma AJCC v8|Stage IIIB Intrahepatic Cholangiocarcinoma AJCC v8|Stage IV Hepatocellular Carcinoma AJCC v8|Stage IV Intrahepatic Cholangiocarcinoma AJCC v8|Stage IVA Hepatocellular Carcinoma AJCC v8|Stage IVB Hepatocellular Carcinoma AJCC v8|Unresectable Cholangiocarcinoma|Unresectable Hepatocellular Carcinoma|Unresectable Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Pevonedistat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Staphylococcus Aureus Colonization of the Posterior Nasal Cavity in Patients Undergoing Otorhinolaryngologic Surgery
Status: COMPLETED
Conditions: Staphylococcal Infections
Interventions: OTHER: Staphylococcus aureus carriage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Oncotool for Cancer Medications
Status: COMPLETED
Conditions: Cancer|Cancer, Treatment-Related|Medication Adherence|Communication|Tyrosine Kinase Inhibitor
Interventions: BEHAVIORAL: Oncotool Intervention (symptom reporting + TKI education)|BEHAVIORAL: Oncotool Control (health information)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Randomized Placebo-controlled Study With Vitamin K2 in Asymptomatic Calcified Carotid Stenosis
Status: UNKNOWN
Conditions: Carotid Disease|Atherosclerosis
Interventions: DRUG: Vitamin K2 (Menaquinone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MRI Guided SBRT for Localized Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: SBRT to whole prostate|RADIATION: IMRT followed by mpMRI guided SBRT boost with SIB to intraprostatic lesions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PREOPERATIVE GONADOTROPINE-RELEASING HORMONE AGONIST THERAPY BEFORE SURGERY FOR UTERİN FIBROIDS
Status: UNKNOWN
Conditions: Uterine Fibroid|Gonadotropin-Releasing Hormone-Dependent Precocious Puberty
Interventions: DRUG: PREOPERATİVE GnRHa THERAPY (LEUPROLIDE ACETATE) BEFORE SURGERY FOR UTERİN FIBROIDS|DRUG: NO GnRHa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Water Soluble Oral Contrast (Gastrografin) on Postoperative Ileus After Colorectal Surgery
Status: COMPLETED
Conditions: Postoperative Ileus
Interventions: DRUG: Gastrografin|DRUG: physiological serum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-term Assessment of Physical Activity, Range of Motion, and Functional Status Following Elective Orthopedic Surgery in Hemophilia Patients With Inhibitors
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A With Inhibitors|Haemophilia B With Inhibitors
Interventions: DRUG: eptacog alfa (activated)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Longitudinal Study of Quality of Life and Activity in Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Lupus Erythematosus
Interventions: OTHER: Questionnaire about quality of life and satisfaction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Placebo-Controlled Study of Mometasone Furoate Nasal Spray (MFNS) 200 mcg QD in the Treatment of Seasonal Allergic Rhinitis (Study P05106)(COMPLETED)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Mometasone furoate nasal spray|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-randomized Prospective Comparison Between SASI Bipartition and RYGB
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity, Morbid|Metabolic Syndrome|Bariatric Surgery Candidate|Postoperative Complications
Interventions: PROCEDURE: SASI Bipartition|PROCEDURE: Gastric bypass
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Local Compression Seroma DIminution Objective (CLODIS)
Status: UNKNOWN
Conditions: Breast Cancer|Mastectomy|Seroma
Interventions: DEVICE: Compression by chest bandage urgo K2®|PROCEDURE: punctures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TAR-200 in Combination With Cetrelimab and Cetrelimab Alone in Participants With Muscle-Invasive Urothelial Carcinoma of the Bladder
Status: RECRUITING
Conditions: Urinary Bladder Neoplasms
Interventions: DRUG: TAR-200|BIOLOGICAL: Cetrelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment and Prevention of Acute Lung Injury (ALI) in Patients With COVID-19 Infection
Status: TERMINATED
Conditions: Acute Lung Injury
Interventions: DRUG: VIB7734|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Follow-up Study With Levetiracetam in Children (4-17 Years Old) Suffering From Absence Seizures
Status: COMPLETED
Conditions: Absence Seizures
Interventions: DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Incidence of Hyperfibrinolysis During Vaginal Delivery and Cesarean Section
Status: RECRUITING
Conditions: Hyperfibrinolysis|Cesarean Section Complications|Coagulation Defect; Bleeding|Peripartum Haemorrhage
Interventions: DIAGNOSTIC_TEST: Coagulation tests (TEG, Levels of F1, F2, hs-D-dimer, Plasminogen, PAI 1+2), SpHb before discharge
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy of Pulmonary Rehabilitation Exercise in Home Care for the Non-invasive Ventilator-dependent Elderly With COPD
Status: COMPLETED
Conditions: Pulmonary Disease
Interventions: OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Expanded Treatment Protocol for Adults With FLT3-ITD Mutated Relapsed or Refractory Acute Myeloid Leukemia (AML) to Receive Quizartinib
Status: NO_LONGER_AVAILABLE
Conditions: Acute Myeloid Leukemia With Gene Mutations
Interventions: DRUG: Quizartinib Dihydrochloride
Study Type: EXPANDED_ACCESS
Clinical trial: The Effect of Heat Therapy on Shoulder Pain and Physiologic Parameters After Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Cholecystectomy|Nursing Caries|Shoulder Pain
Interventions: OTHER: Heat Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using Transcranial Alternating Current Stimulation to Improve Executive Function in 22q11.2 Deletion Syndrome
Status: RECRUITING
Conditions: 22Q11 Deletion Syndrome|tACS
Interventions: DEVICE: at-home tACS using Starstim-Home tES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Auricular Acupressure Integrated With Mobile Device for Weight Reduction
Status: COMPLETED
Conditions: Obesity|Weight Loss|Mobile Application|Ear Acupressure
Interventions: OTHER: Auricular acupressure plus smartphone App|OTHER: Auricular acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Indocyanine Green Fluorescence Imaging, Sentinel Lymph Node Mapping in Patients With Vulvar Cancer
Status: UNKNOWN
Conditions: Vulvar Cancer
Interventions: OTHER: Sentinel lymph node mapping with indocyanine green fluorescence imaging in vulvar cancer (FIGO Stage IB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study of OurRelationship.dk, a Web-based Self-help-Program for Couples With High Levels of Conflict or Distress
Status: UNKNOWN
Conditions: Relationship Distress|Marital Conflict|Family Relationship
Interventions: BEHAVIORAL: The online self-help Program OurRelationship developed by prof. Brian Doss and prof. Andrew Christensen.|BEHAVIORAL: The off line self-help course "Pas på Parforholdet".
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Additives to Prevent Post Spinal Shivering in Transurethral Prostatectomy
Status: UNKNOWN
Conditions: Anesthesia
Interventions: DRUG: Drug:dexamethasone in group Dexamethasone,fentanyl in group Fentanyl,normal saline 0.9%in group Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Efficacy and Safety of VVZ-149 Injections for the Treatment of Postoperative Pain Following Bunionectomy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: VVZ-149 Injections|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Respiratory Biofeedback Device and Reduction of Dental Anxiety Associated With Local Anesthesia in Children
Status: COMPLETED
Conditions: Anxiety
Interventions: DEVICE: RESPeRATE™|BEHAVIORAL: Tell, Show and Do technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improvement of Support to Caregivers of Cancer Patients in Basic Palliative Care at Home
Status: UNKNOWN
Conditions: Palliative Care
Interventions: BEHAVIORAL: The Carer Support Needs Assessment Tool (CSNAT) intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dose-escalation Study of Safety of PBCAR19B in Participants With CD19-expressing Malignancies
Status: COMPLETED
Conditions: CD19 Expressing Malignancies|Hematologic Malignancy
Interventions: GENETIC: PBCAR19B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MEDI4736 (Anti PD-L1) Combined With Gefitinib in Subjects With Non-Small Cell Lung Cancer(NSCLC).
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Gefitinib|DRUG: MEDI4736
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Evaluation of Probiotic Product on Bowel Habits in Healthy Subjects
Status: COMPLETED
Conditions: Constipation
Interventions: DIETARY_SUPPLEMENT: Fermented milk containing Lactobacillus casei strain Shirota|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Systemic Pharmacokinetics, Metabolism and Excretion Routes of YM178 in Man, After Administration of Radio-labeled YM178
Status: COMPLETED
Conditions: Metabolic Processes
Interventions: DRUG: 14C-labeled YM178
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Early Postoperative Complications in Patients Undergoing Bariatric Surgery
Status: RECRUITING
Conditions: Bariatric Surgery Candidate|Complication,Postoperative
Interventions: PROCEDURE: Sleeve gastrectomy, Roux-en-Y gastric bypass, mini-gastric bypass, SADIS, intragastric balloon insertion, and gastric band placement are bariatric surgeries.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Initial Study of Insomnia/Nightmare Group Treatment for Posttraumatic Stress Disorder (PTSD)
Status: UNKNOWN
Conditions: Insomnia|Nightmares|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Cognitive-Behavioral Insomnia and Nightmare Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telephone vs. Voice Over IP Speech Comprehension in Hearing Aided Subjects.
Status: TERMINATED
Conditions: Hearing-Impairment
Interventions: DEVICE: Conventional acoustic telephony|DEVICE: Conventional bluetooth telephony|DEVICE: VoIP acoustic telephony|DEVICE: VoIP bluetooth telephony
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Assess the Excretion Balance and Pharmacokinetics of a Single Oral Dose of [14C]GW856553 in Healthy Adult Males
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GW856553
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the ECG Effects of Telaglenastat in Healthy Adult Subjects
Status: COMPLETED
Conditions: Cardiac Safety
Interventions: DRUG: telaglenastat|OTHER: telaglenastat placebo|OTHER: moxifloxicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pantoprazole in Cisplatin Nephrotoxicity
Status: RECRUITING
Conditions: Oncology
Interventions: DRUG: Pantoprazole low dose|DRUG: Pantoprazole high dose|OTHER: Standard hydration|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Iron Absorption From Iron-enriched Aspergillus Oryzae
Status: COMPLETED
Conditions: Iron-deficiency|Absorption; Iron|Anemia, Iron Deficiency|Bioavailability|Serum Iron
Interventions: DIETARY_SUPPLEMENT: Ferrous sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High-flow Nasal Oxygenation During Preoxygenation and Atelectasis
Status: RECRUITING
Conditions: Anesthesia, General|Pulmonary Atelectasis
Interventions: OTHER: high-flow nasal oxygen|OTHER: facemask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Eccentric Training in Hypoxia With Creatine on Metabolic Control and VO2max in Patients With Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: hypoxia|BEHAVIORAL: normoxia|DIETARY_SUPPLEMENT: creatine supplementation|DIETARY_SUPPLEMENT: no creatine supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zein Nanoparticles for Glycemic Control
Status: COMPLETED
Conditions: PreDiabetes|Overweight and Obesity|Adult ALL
Interventions: DIETARY_SUPPLEMENT: Zein nanocapsules|DIETARY_SUPPLEMENT: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Calcium Channel Blockers and Adenosine in the Emergency Management of SVT
Status: COMPLETED
Conditions: Supraventricular Tachycardia
Interventions: DRUG: Calcium Channel Blocker & Adenosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Hypertonic Saline Solution (NACL 3%+NAHCO3) on Nasal Inflammation in Children With AR. RinASol- Pilot Study
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: hypertonic saline solution (NACL 3%+NAHCO3)|OTHER: Saline Solution (NACL 0,9%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Effect of PTH134 at Increasing Doses in Healthy Postmenopausal Subjects
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: PTH134
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tebentafusp in HLA-A*0201 Positive Previously Untreated Metastatic Uveal Melanoma
Status: NOT_YET_RECRUITING
Conditions: Uveal Melanoma
Interventions: DRUG: Tebentafusp
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Brentuximab Vedotin Combined With RCHOP or RCHP in Front-line Treatment of Patients With Diffuse Large B-cell Lymphoma (DLBCL)
Status: TERMINATED
Conditions: Lymphoma, B-cell|Lymphoma, Large B-cell, Diffuse
Interventions: DRUG: brentuximab vedotin|DRUG: brentuximab vedotin|DRUG: rituximab|DRUG: vincristine|DRUG: cyclophosphamide|DRUG: prednisone|DRUG: doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality to Improve Social Perspective Taking
Status: COMPLETED
Conditions: Conduct Disorder|Child|Adolescent|Attention Deficit and Disruptive Behavior Disorders|Child Behavior Disorders|Virtual Reality|Social Perception|Magnetic Resonance Imaging
Interventions: DEVICE: Virtual reality perspective taking training|DEVICE: Virtual reality control perspective
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of INS50589 Intravenous Infusion in Subjects Undergoing Coronary Artery Bypass Grafting (CABG) Involving Cardiopulmonary Bypass
Status: TERMINATED
Conditions: Coronary Disease
Interventions: DRUG: INS50589 Intravenous Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: CABAzitaxel With or Without Prednisone in Patients With Metastatic CAstration REsistant Prostate Cancer Progressed During or After a Previous Docetaxel-based Chemotherapy
Status: UNKNOWN
Conditions: Prostate Cancer|Castration-resistant Prostate Cancer
Interventions: DRUG: Cabazitaxel|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Supernormal Oxygen Delivery for Patients With Severe Burns
Status: UNKNOWN
Conditions: Burn Surgery|Dobutamine
Interventions: DRUG: Dobutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Testosterone Therapy in Men With Alzheimer's Disease and Low Testosterone
Status: COMPLETED
Conditions: Alzheimer's Disease|Hypogonadism
Interventions: DRUG: AndroGel (Solvay Pharmaceuticals)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Arteriovenous Fistula Simulation Study (ShuntSimulationStudy)
Status: COMPLETED
Conditions: Kidney Failure, Chronic|Arteriovenous Fistulae
Interventions: DEVICE: AVF-simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Motor Coordination and Grip Strength of the Dominant and Non-dominant Hand and Wrist in Post-stroke Patients.
Status: COMPLETED
Conditions: Stroke
Interventions: PROCEDURE: hand motor coordination in a sitting positin|PROCEDURE: hand motor coordination in a supine position
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Terbinafine Treatment of Axial Spondyloarthropathy
Status: WITHDRAWN
Conditions: Ankylosing Spondylitis|Axial Spondyloarthritis|Psoriatic Spondylitis|Spondylitis Secondary to Inflammatory Bowel Disease|Axial Spondyloarthopathy
Interventions: DRUG: Terbinafine Tablets|DIAGNOSTIC_TEST: Laboratory Testing|DIAGNOSTIC_TEST: Laboratory Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Indocyanine Green Cholangiography and Methylene Blue to Detect Postoperative Biliary Fistula After Hepatectomy
Status: UNKNOWN
Conditions: Liver Disease
Interventions: PROCEDURE: indocyanine green fluorescent cholangiography|DRUG: methylene blue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of PK After Administration of HCP1201 and Co-administration of Metformin SR 750mg and Rosuvastatin 20mg
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: HCP1201 750/20mg|DRUG: Metformin SR 750mg|DRUG: Rosuvastatin 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Glipizide to Treat High Blood Sugar in People With Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer|Pancreatic Carcinoma|Pancreatic Ductal Adenocarcinoma|Pancreatic Cancer Metastatic|Metastatic Pancreatic Cancer|Metastatic Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Glipizide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Timing of Estrogen Support During the Luteal Phase of in Vitro Fertilization (IVF)/Intracytoplasmic Sperm Injection (ICSI) Cycle
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: estradiol tablet|DRUG: estradiol tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing the Dose of Flucytosine for the Treatment of Cryptococcal Meningitis
Status: RECRUITING
Conditions: Cryptococcal Meningitis
Interventions: DRUG: AMBITION trial control|DRUG: Flucytosine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab After Autologous Stem Cell Transplant for Relapsed B-cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Diffuse Large Cell Lymphoma|Mantle Cell Lymphoma|Transformed Lymphoma|Other Subtypes of B-cell Lymphoma|Lymphoma
Interventions: DRUG: Rituximab 375 mg/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Isoflurane on Tissue Doppler Imaging of Mitral Annulus During Cardiac Surgery
Status: COMPLETED
Conditions: Valvular Heart Disease|Ischemic Heart Disease
Interventions: DRUG: Isoflurane 1.0 MAC|DRUG: Isoflurane 1.5 MAC|DRUG: Isoflurane 2.0 MAC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Immunogenicity, Safety and Tolerability of MEDI3506 in Health Chinese Participants
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: BIOLOGICAL: MEDI3506|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Metformin Versus Acarbose Treatment in Infertile Overweight Women With Polycystic Ovary Syndrome (PCOS)
Status: COMPLETED
Conditions: PCO
Interventions: DRUG: Metformin|DRUG: Acarbose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparing Cytokines, Toxins Adsorbing oXiris Filter to ST150 Filter During CRRT in Patients With Septic Shock
Status: COMPLETED
Conditions: Septic Shock|Acute Kidney Injury
Interventions: DEVICE: oXiris
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Radiotherapy After Complete Resection of Liver Metastases in Patient With Digestive Neuroendocrine Tumor
Status: TERMINATED
Conditions: Digestive Neuroendocrine Tumors|Metabolic Radiotherapy|Resection|Liver Metastases
Interventions: DRUG: In111-Pentetréotide|OTHER: simple monitoring without active therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of TASC C and D Aortoiliac Lesions
Status: RECRUITING
Conditions: Peripheral Arterial Disease|Aortoiliac Occlusive Disease|Leriche Syndrome|Peripheral Vascular Disease
Interventions: PROCEDURE: Open surgery|PROCEDURE: Hybrid repair|PROCEDURE: Endovascular repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Study on the Efficacy of OliNano SEAL and Curodont D' Senz in Treatment of Dentin Hypersensitivity
Status: COMPLETED
Conditions: Dentin Hypersensitivity
Interventions: DRUG: Olinanoseal|DRUG: Curodont D'senz
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Chinese Domestic Surgical Robot System in Urological Telesurgery
Status: RECRUITING
Conditions: Renal Cell Carcinoma|Adrenal Tumor|Nonfunctioning Kidney|Renal Pelvis Carcinoma|Ureteral Tumor|Bladder Cancer|Prostate Cancer|Pelvic Tumor|Renal Cyst|Duplex Kidney|Renal Calculi|Ureteral Calculi|Ureteropelvic Junction Obstruction|Penile Cancer
Interventions: DEVICE: telesurgery by domestic surgical robot
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mindfulness for Pain and Suicide
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain|Suicidal Ideation|Suicide, Attempted|Opioid Use
Interventions: BEHAVIORAL: Mindfulness-Based Cognitive Therapy (MBCT)|BEHAVIORAL: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PDGFR Inhibitor Crenolanib in Children/Young Adults With Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade Glioma
Status: COMPLETED
Conditions: Diffuse Intrinsic Pontine Glioma|Progressive or Refractory High-Grade Glioma
Interventions: DRUG: Crenolanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influenza Vaccine in HIV Infected Children
Status: COMPLETED
Conditions: Influenza With Pneumonia, Influenza Virus Identified
Interventions: BIOLOGICAL: Trivalent sub-unit influenza vaccine|BIOLOGICAL: Saline, 0.5ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Grapiprant (ARY-007) and Pembrolizumab in Patients With Advanced or Metastatic Post-PD-1/L1 NSCLC Adenocarcinoma
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer Adenocarcinoma
Interventions: DRUG: grapiprant and pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIPEC and Systemic Chemotherapy in Unresectable Peritoneal Metastases From Colorectal Cancer
Status: TERMINATED
Conditions: Peritoneal Metastases From Colorectal Cancer
Interventions: PROCEDURE: exploratory laparoscopy or laparotomy|PROCEDURE: HIPEC|DRUG: Systemic chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Efficacy of Enbrel Administered by Sofusa DoseConnect for Rheumatoid Arthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DEVICE: Sofusa DoseConnect|DRUG: Enbrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polatuzumab Vedotin in Combination With Chemotherapy in Subjects With Richter's Transformation
Status: RECRUITING
Conditions: Richter Syndrome|Chronic Lymphocytic Leukemia
Interventions: DRUG: Polatuzumab Vedotin|DRUG: Rituximab|DRUG: Etoposide|DRUG: Prednisone|DRUG: Cyclophosphamide|DRUG: Hydroxydaunomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Metabolic Changes in the Transformation Malignant Precancerous Skin Lesions
Status: RECRUITING
Conditions: Cutaneous Squamous Cell Carcinoma|Basal Cell Carcinomas
Interventions: OTHER: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Low-dose Percutaneous Electrical Stimulation in Patients With Erectile Dysfunction.
Status: ACTIVE_NOT_RECRUITING
Conditions: Pudendal Nerve Injury|Erectile Dysfunction|Electric Stimulation
Interventions: OTHER: Low Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adrenal Responsiveness During the Perioperative Period in Children Undergoing Congenital Cardiac Surgery
Status: COMPLETED
Conditions: Adrenal Cortex Diseases|Infant Morbidity
Interventions: DRUG: Cosyntropin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of First-line Single-agent Panitumumab in Frail Elderly Patients With Advanced Wild Type K-RAS Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Speckle Contrast Imaging for Cutaneous Microvascular Dysfunction Detection in Systemic Sclerosis.
Status: COMPLETED
Conditions: Raynaud Disease|Scleroderma, Systemic
Interventions: PROCEDURE: laser speckle contrast imaging|PROCEDURE: Cooling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: 131I-L19SIP Radioimmunotherapy Combined With Radiochemotherapy in Patients With Locally-advanced Non Small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: OTHER: 131I-L19SIP Radioimmunotherapy (RIT) in Combination With External Beam Radiotherapy (EBRT) and Concurrent Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Different Ways of Steroid Administration After Total Knee Implantation
Status: RECRUITING
Conditions: Total Knee Replacement
Interventions: DRUG: Dexamethasone Sodium Phosphate 4 mg/ml intravenous|DRUG: Dexamethasone Sodium Phosphate 4 mg/ml intra-articular
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study for Therapy of Locally Advanced or Metastatic Non Small Cell Lung Cancer (NSCLC) With Cisplatin / Docetaxel or Oxaliplatin / Docetaxel
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Cisplatin|DRUG: Oxaliplatin|DRUG: Docetaxel|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ability of Beta-glucan Supplementation to Augment Immune Function
Status: COMPLETED
Conditions: Cold|Cold Symptom|Flu|Flu Symptom|Supplement|Stress|Gastrointestinal Tolerance
Interventions: DIETARY_SUPPLEMENT: Beta-Glucan|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Initial Stay Times and Heat Mitigation Controls for Uncompensable Occupational Heat Stress - Part I
Status: COMPLETED
Conditions: Core Temperature|Heat Stress, Exertional|Heat Fatigue|Exercise
Interventions: OTHER: Simulated work in the heat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma
Status: RECRUITING
Conditions: WHO Grade 3 Glioma|WHO Grade 4 Glioma
Interventions: PROCEDURE: Computed Tomography|OTHER: Electronic Health Record Review|DRUG: Ga 68 PSMA-11|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Clinical and Subjective Performance of Three Different MPDS With Silicon Hydrogel Lenses
Status: COMPLETED
Conditions: Adverse Reaction to Contact Lens Solution
Interventions: DEVICE: Contact lens care solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Antineoplaston Therapy in Treating Patients With Recurrent or Refractory Waldenstrom's Macroglobulinemia
Status: WITHDRAWN
Conditions: Waldenstrom Macroglobulinemia
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Titanium Platelet-rich Fibrin in Sinus Floor Elevation Through Flapless Transcrestal Approach
Status: COMPLETED
Conditions: Sinus Floor Elevation
Interventions: OTHER: Flapless transcrestal sinus lift approach with TPRF|OTHER: Flapless transcrestal sinus lift approach with PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: N-acetyl Cysteine in Post-reperfusion Pulmonary Injury in Chronic Thromboembolic Pulmonary Hypertension.
Status: UNKNOWN
Conditions: Chronic Thromboembolic Pulmonary Hypertension
Interventions: DRUG: N-acetyl cysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Three Doses of TCH346 in Patients With Early Parkinson's Disease to Evaluate Safety and Efficacy
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: TCH346 (dibenz[b,f]oxepin-10-ylmethyl-prop-2-ynyl-amine, hydrogen maleate salt)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Vitamin K Supplementation Study in Healthy Volunteers (Aim 2B)
Status: TERMINATED
Conditions: Vitamin K Status
Interventions: GENETIC: Phase I, Buccal Swab Collection for DNA Isolation|DIETARY_SUPPLEMENT: Phase II, Vitamin K (Vitacost) Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low-Dose Dobutamine Tc-99m-Mibi Gated SPECT to Predict Left Ventricular Remodelling in Patients Reperfused in the Acute Phase of MI
Status: COMPLETED
Conditions: Ischemic Heart Disease|Myocardial Infarction
Interventions: PROCEDURE: Low-dose dobutamine Tc-99-m-mibi gated SPECT imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Phase Pre-Clinical and Initial Clinical Research on Epicatechin (Part 2)
Status: COMPLETED
Conditions: Pre-diabetes
Interventions: DRUG: epicatechin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Pharmacodynamics and Safety of LY01005 in Patients With Prostate Cancer Compared to ZOLADEX®
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: LY01005|DRUG: ZOLADEX® 3.6 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-dose Radiotherapy Combined With Durvalumab, Chemotherapy(EP) in the Treatment of ES-SCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer|Extensive-stage Small-cell Lung Cancer|Durvalumab
Interventions: RADIATION: Low-dose radiotherapy|DRUG: Durvalumab|DRUG: Etoposide, and cisplatin/carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Approval Pharmacokinetic Study of Loratadine in Japanese Pediatric and Adult Patients (Study P05539)
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: loratadine|DRUG: loratadine|DRUG: loratadine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Erector Spinae Plane (ESP) and Transversus Abdominis Plane (TAP) Block in Inguinal Hernia
Status: COMPLETED
Conditions: Inguinal Hernia|Postoperative Pain|Anesthesia, Local|Anesthesia Complication
Interventions: PROCEDURE: ESP block|PROCEDURE: TAP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intralesional Cemiplimab for Adult Patients With Cutaneous Squamous Cell Carcinoma or Basal Cell Carcinoma
Status: RECRUITING
Conditions: Cutaneous Squamous Cell Carcinoma|Basal Cell Carcinoma
Interventions: DRUG: Cemiplimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vericiguat on Peripheral Vascular Function, Patient Health Status and Inflammation
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure|Heart Failure With Reduced Ejection Fraction (HFrEF)
Interventions: DRUG: Vericiguat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Analgesic Effects of Cheek Acupuncture for Acute Gouty Arthritis
Status: COMPLETED
Conditions: Acute Gout Arthritis|Acupuncture|Acute Pain
Interventions: OTHER: cheek acupuncture|DRUG: Etoricoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ramucirumab Use in Combination With Paclitaxel in Gastric or Gastroesophageal Junction Adenocarcinoma; Temporary Authorization for Use (ATU) in France
Status: NO_LONGER_AVAILABLE
Conditions: Gastric Cancer|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Ramucirumab|DRUG: Paclitaxel
Study Type: EXPANDED_ACCESS
Clinical trial: An Efficacy Study of Trabectedin in the Treatment of Participants With Specific Subtypes of Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Dexamethasone|DRUG: Trabectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of Endoscopic Assessment of Gastroesophageal Reflux and Barretts Esophagus
Status: COMPLETED
Conditions: Barrett's Esophagus
Interventions: DEVICE: Sedated Endoscopy|DEVICE: Transnasal Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Modified Story Memory Technique (mSMT) in Persons With TBI
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: Group Memory retraining exercises|BEHAVIORAL: Placebo controlled group memory exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gamified Digital Intervention to Enhance the Efficacy of Exposure Therapy for OCD
Status: NOT_YET_RECRUITING
Conditions: Experimental Video Games|Behavioral Assessment
Interventions: DEVICE: Gamified Digital Intervention - Feasibility Analysis on MoM|DEVICE: Gamified Digital Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments
Status: COMPLETED
Conditions: Vestibulodynia|Temporomandibular Disorder|Fibromyalgia Syndrome|Irritable Bowel Syndrome|Migraines|Tension Headache|Endometriosis|Interstitial Cystitis|Back Pain|Chronic Fatigue Syndrome
Interventions: DRUG: 5% lidocaine/5 mg/ml 0.02% estradiol compound cream|DRUG: Nortriptyline|DRUG: Placebo cream|DRUG: Placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating B Cell Levels In Infants Potentially Exposed To Ocrelizumab During Pregnancy
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis|Clinically Isolated Syndrome
Interventions: DRUG: Ocrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Infant Mortality Reduction by the Mass Administration of Azithromycin
Status: RECRUITING
Conditions: Child Mortality
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Timing of Surgery and Chemotherapy in Treating Patients With Newly Diagnosed Advanced Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Oral BG00012 in Relapsing-Remitting Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: BG00012|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT