pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Phase I/II Trial of Intracerebral IL13-PE38QQR Infusions in Pediatric Patients With Recurrent Malignant Glioma
Status: WITHDRAWN
Conditions: Recurrent Malignant Glioma
Interventions: DRUG: IL13-PE38QQR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Physical Fatigue on Lower Limb Functional Performance Tests in a Healthy Population
Status: COMPLETED
Conditions: Physical Fatigue|Return to Sport|Injury Prevention|Functional Performance
Interventions: BEHAVIORAL: Physical Fatigue|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Effect Site Concentration of Remifentanil for Preventing Cough During Emergence Between Male and Female Patients With Thyroidectomy
Status: COMPLETED
Conditions: Patients Undergoing Thyroidectomy
Interventions: DRUG: up-and-down method to find out effective concentration of remifentanil for preventing cough during emergence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Progesterone in Threatened Abortion
Status: TERMINATED
Conditions: Threatened Abortion in First Trimester
Interventions: DRUG: Progesterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epiduo Pediatric Acne Study
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: adapalene/benzoyl peroxide|DRUG: Topical Gel Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: INVESTIGATION OF THE EFFECT OF SOLUTION-FOCUSED APPROACH TRAINING ON TRAUMATIC BIRTH PERCEPTION, VAGINAL BIRTH SELF-EFFICACY AND BIRTH TYPE PREFERENCE.
Status: RECRUITING
Conditions: Traumatic Birth|Self Efficacy|Perception, Self
Interventions: BEHAVIORAL: solution focused approach training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Understanding Community Considerations, Opinions, Values, Impacts, and Decisions for COVID-19
Status: COMPLETED
Conditions: Covid-19|Critical Illness|Attitude of Health Personnel|Attitude to Health|Health Behavior|Health Care Utilization
Interventions: BEHAVIORAL: Brief educational video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Investigation of a Physiotherapist and Nurse Practitioner Intervention for Chronic Low Back Disorders Delivered Through Telehealth
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: OTHER: NP face to face management of Chronic Low Back Pain|OTHER: PT face to face management of Chronic Low Back Pain|OTHER: Interprofessional Videoconferencing for Chronic Low Back Pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ASP2215 (Gilteritinib) by Itself, ASP2215 Combined With Azacitidine or Azacitidine by Itself to Treat Adult Patients Who Have Recently Been Diagnosed With Acute Myeloid Leukemia With a FLT3 Gene Mutation and Who Cannot Receive Standard Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia (AML)|Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) Mutation
Interventions: DRUG: gilteritinib|DRUG: azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Teleexercise for Rotator Cuff Syndrome: A Comparison
Status: COMPLETED
Conditions: Rotator Cuff Syndrome
Interventions: OTHER: Remote Monitoring of Participant Progress and Well-being via Video Calls|OTHER: Face-to-Face Clinic-based Monitoring of Participant Progress and Well-being
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Complications Associated With Primary Placement of Gastrostomy for Feeding
Status: COMPLETED
Conditions: Gastrostomy Tube
Interventions: PROCEDURE: Percutaneous endoscopic gastrostomy|PROCEDURE: Radiologically-inserted gastrostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized Controlled Trial of Electrical Stimulation to Treat Pelvic Floor Disorder
Status: RECRUITING
Conditions: Pelvic Organ Prolapse|Incontinence
Interventions: DEVICE: Electrical Stimulation|DEVICE: Biofeedback|OTHER: Pelvic Floor Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of LCI699 Compared to Placebo in Participants With Resistant Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: LCI699|DRUG: Eplerenone|DRUG: LCI699-matching Placebo|DRUG: Eplerenone-matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: I-scan With Magnification for the Detection of Gastric Intestinal Metaplasia
Status: UNKNOWN
Conditions: Gastric Intestinal Metaplasia
Interventions: DEVICE: I-scan with magnification|DEVICE: Standard endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Local Metabolism of the Gastric Tube Reconstruction After Esophagectomy
Status: COMPLETED
Conditions: Microdialysis|Ischemia|Anastomotic Leakage
Interventions: DEVICE: OnZurf Probe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: TMC435-TiDP16-C126 - Trial to Investigate the Effect of Severe Renal Impairment on the Pharmacokinetics and Safety of TMC435
Status: COMPLETED
Conditions: Hepatitis C Virus
Interventions: DRUG: TMC435
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effects of AT-527 in Non-Hospitalized Adult Patients With Mild or Moderate COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: AT-527|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Conventional Endoscopic Mucosal Resection vs Underwater Resection for Colorectal Non-pedunculated Colorectal Lesions
Status: COMPLETED
Conditions: Adenoma|Colorectal Neoplasms
Interventions: PROCEDURE: Conventional Endoscopic Mucosal Resection|PROCEDURE: Underwater Endoscopic Mucosal Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Epinephrine and Phenylephrine/Ketorolac With Regards to Pupil Size
Status: TERMINATED
Conditions: Cataract
Interventions: DRUG: Phenylephrine-ketorolac|DRUG: Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Value of the Laparoscopic Approach in the Surgical Management of Resectable Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Laparoscopy|PROCEDURE: Laparotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real-World Evaluation of Omarigliptin for Type 2 Diabetes Meliitus in Bangladesh
Status: NOT_YET_RECRUITING
Conditions: Type2diabetes
Interventions: DRUG: Omarigliptin|DRUG: Sulphonylureas|DRUG: Metformin|DRUG: Other DPP4-i|DRUG: Thiazolidinediones|DRUG: Alpha-Glucosidase Inhibitor|DRUG: Glucagon-Like Peptide-1|DRUG: Receptor Agonists (GLP1RA)|DRUG: SGLT2 inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Autologous T Cells to Express T-Cell Receptors (TCRs) in Subjects With Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Gynecologic Cancer|Colorectal Cancer|Pancreatic Cancer|Non-small Cell Lung Cancer|Cholangiocarcinoma|Ovarian Cancer|Endometrial Cancer|Ovarian Carcinoma|Ovary Neoplasm|Squamous Cell Lung Cancer|Adenocarcinoma of Lung|Adenosquamous Cell Lung Cancer
Interventions: BIOLOGICAL: Neoantigen specific TCR-T cell drug product|BIOLOGICAL: Aldesleukin (IL-2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healing of Bone/Soft Tissue to Different Abutment Biomaterials and the Impact on Marginal Bone Loss
Status: COMPLETED
Conditions: Bone Loss|Inflammation
Interventions: DEVICE: dental implants|DEVICE: Zirconia abutments|DEVICE: Titanium Abutments|DEVICE: cad-cam acrylic abutments|PROCEDURE: Subcrestal|DEVICE: platform-switch|PROCEDURE: one-time one-abutment|PROCEDURE: Torque 20 n/cm2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, Effectiveness and Absorption of Exodif™ Tablets in Clostridium Difficile-associated Diarrhea
Status: TERMINATED
Conditions: Enterocolitis, Pseudomembranous|Diarrhea|Clostridium Difficile
Interventions: DRUG: GT267-004 (tolevamer potassium sodium)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CLAIR -FO: Clinical Trial of Ophthalmic Insert Mydriasert® Versus Reference Treatment
Status: TERMINATED
Conditions: Retinal Anomalies|Premature Birth
Interventions: DRUG: Mydriasert®|DRUG: phenylephrine and tropicamide eyedrops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Bed up Head Elevated Position With Sniffing Position in Rapid Sequence Induction.
Status: UNKNOWN
Conditions: Endotracheal Intubation in Bed up Head Elevation Position in Rapid Sequence Induction
Interventions: OTHER: comparison between two different intubating position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of a Basal/Pre-Meal Insulin Strategy (Detemir/Aspart) on Insulin Secretion and Action in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Long-acting bedtime insulin detemir (Levemir)|DRUG: Insulin detemir and pre-meal insulin aspart.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurocognitive Outcome in Children Who Suffered From Idiopathic Increased Intracranial Hypertension (IIH)
Status: UNKNOWN
Conditions: Prospective Study , Questionaires
Interventions: BEHAVIORAL: neurocognitive tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Atrial Fibrillation Patient Preference Study
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: VKA: Warfarin (Waran)|DRUG: NOAC: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: NOAC: Dabigatran etexilate|DRUG: NOAC: Apixaban|DRUG: NOAC: Edoxaban|DRUG: NOAC: Lixiana
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Versus Low LMWH Dosages in Hospitalized Patients With Severe COVID-19 Pneumonia and Coagulopathy
Status: UNKNOWN
Conditions: COVID|Pneumonia, Viral|Coagulation Disorder
Interventions: DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of the Effects of Colgate Total Toothpaste as Compared to a Matching Placebo on Periodontal Disease and Systemic Inflammatory Markers
Status: COMPLETED
Conditions: Periodontal Disease|Systemic Inflammatory Markers
Interventions: DRUG: Triclosan Containing Toothpaste|DRUG: Triclosan Free Toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Haploidentical Hematopoietic Stem Cell Transplantation Using A Novel Clofarabine Containing Conditioning Regimen For Patients With Refractory Hematologic Malignancies
Status: COMPLETED
Conditions: Hematologic Malignancies
Interventions: DRUG: Clofarabine|PROCEDURE: Stem Cell Transplantation, Hematopoietic|OTHER: OKT3|DRUG: Thiotepa|DRUG: Melphalan|DRUG: Mycophenolate mofetil|DRUG: Rituximab|OTHER: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk
Status: RECRUITING
Conditions: Psychosis|Prodromal Schizophrenia|Prodromal Symptoms
Interventions: BEHAVIORAL: SCORES (Specific COgnitive Remediation with Support)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Electroacupuncture and Trancutaneous Electrical Nervous Stimulation (TENS) for Colonoscopy Analgesia
Status: COMPLETED
Conditions: Pain
Interventions: OTHER: Acupuncture|OTHER: Transcutaneous electrical stimulation|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DynaCleft® Effects on Soft Tissues and on Quality of Life for Incomplete Unilateral Cleft Lip Infants
Status: RECRUITING
Conditions: Cleft Lip and Palate
Interventions: OTHER: Comparator: Retrospective Group(Control)|DEVICE: Prospective Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Pilot Study Comparing NatrOVA Creme Rinse 1% and NIX Creme Rinse
Status: COMPLETED
Conditions: Pediculosis Capitis|Head Lice
Interventions: DRUG: NatrOVA Creme Rinse - 1%|DRUG: NIX Creme Rinse - 1% permethrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tissue Characterization and Primary Percutaneous Coronary Intervention Guidance Using Intravascular Ultrasound
Status: ACTIVE_NOT_RECRUITING
Conditions: ST Elevation Myocardial Infarction|Acute Myocardial Infarction|Coronary Artery Disease|Percutaneous Coronary Intervention|Intravascular Ultrasound|Thrombus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Examine Multiple Doses of TMC647055 in Combination With Telaprevir
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: TMC647055|DRUG: TMC647055|DRUG: TVR|DRUG: TVR|DRUG: TVR|DRUG: PegFN|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Operations and Pelvic Muscle Training in the Management of Apical Support Loss: The OPTIMAL Trial
Status: COMPLETED
Conditions: Pelvic Organ Prolapse (POP)
Interventions: PROCEDURE: SSLF|PROCEDURE: ULS|BEHAVIORAL: PMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Adjuvant Chemotherapy for Gastric Cancer
Status: COMPLETED
Conditions: Stomach Cancer
Interventions: DRUG: Mitomycin, doxifluridine and cisplatin|DRUG: Mitomycin and doxifluridine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of YM150 for Prevention of Venous Thromboembolism in Patients Undergoing Major Abdominal Surgery
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: YM150|PROCEDURE: mechanical prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: In-vivo Comparison of Different Levels of Femoral Rollback in a Primary Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Gonarthrosis
Interventions: DEVICE: ATTUNE® Knee System|DEVICE: PFC® SIGMA® Knee System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: The Effectiveness of Patient-tailored Treatment in Patients With (Sub)Acute Neck Pain
Status: COMPLETED
Conditions: Neck Pain|Acute Pain|Rehabilitation|Physical Therapy Modalities
Interventions: OTHER: patient-tailored therapy|OTHER: Non-patient tailored therapy: generalized exercise program|OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Periodontal Therapy on Systemic Inflammation
Status: COMPLETED
Conditions: Periodontal Disease|Cardiovascular Disease|Type 2 Diabetes|Obesity|Metabolic Syndrome
Interventions: PROCEDURE: metronidazole and amoxicillin|PROCEDURE: Two placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Healthy Volunteer Study to Compare Fezagepras (PBI-4050) With Sodium Phenylbutyrate
Status: TERMINATED
Conditions: Hyperammonemia
Interventions: DRUG: Fezagepras|DRUG: Sodium phenylbutyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of QL1101 and Avastin® Respectively Combined With Paclitaxel and Carboplatin in the First-line Treatment of Non-squamous Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-squamous Non-small Cell Lung Cancer
Interventions: DRUG: QL1101|DRUG: Avastin®|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antenatal Depression Help-seeking Trial in Eswatini
Status: RECRUITING
Conditions: Help-Seeking Behavior|Help-seeking Intention|Antenatal Depression
Interventions: BEHAVIORAL: Mommy ReachOut Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Topical Antibiotic Prophylaxis for Nasal Packing Post-ESBS
Status: WITHDRAWN
Conditions: Intracranial Pathology
Interventions: COMBINATION_PRODUCT: Antibiotic Irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Laparoscopic Hill and Laparoscopic Nissen Anti-Reflux Procedures
Status: COMPLETED
Conditions: Gastroesophageal Reflux|Esophageal Reflux|Gastroesophageal Reflux Disease|GERD
Interventions: PROCEDURE: Laparoscopic Hill Repair|PROCEDURE: Laparoscopic Nissen Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Peer-Supported Online Problem-Solving Program
Status: COMPLETED
Conditions: Problem-solving|Well-being|Peer Support|Online Mental Health Program
Interventions: OTHER: Moving Forward On Your Own|BEHAVIORAL: Moving Forward with Peer Support|BEHAVIORAL: Wait
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Investigate Atezolizumab and Chemotherapy Compared With Placebo and Chemotherapy in the Neoadjuvant Setting in Participants With Early Stage Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Triple-negative Breast Cancer
Interventions: DRUG: Atezolizumab (MPDL3280A), an engineered anti-PDL1 antibody|DRUG: Placebo|DRUG: Nab-paclitaxel|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Filgrastim|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Integration of Refugees Into Public Mental Health Care
Status: UNKNOWN
Conditions: Psychiatric Disorders From Chapters 3 and 4 of ICD10
Interventions: OTHER: "coordinated and peer supported mental health care"|BEHAVIORAL: "standard psychotherapeutic care in the public healthcare system"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Rosiglitazone on the Metabolic Phenotype of Impaired Glucose Tolerance in Youth
Status: COMPLETED
Conditions: Obesity|Impaired Glucose Tolerance|Type 2 Diabetes Mellitus
Interventions: DRUG: Rosiglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neurotropin Treatment of Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Placebo|DRUG: Neurotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rivastigmine Study in Adolescents With Down Syndrome
Status: COMPLETED
Conditions: Down Syndrome
Interventions: DRUG: Rivastigmine|OTHER: Liquid Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Are Superficial Parasternal Intercostal Plane (SPIP) Blocks With Bupivacaine and With or Without Transversus Abdominis Plane Block (TAP) Helpful for Post-operative Pain After Coronary Artery Bypass Grafting?
Status: UNKNOWN
Conditions: Post-operative Pain Management
Interventions: PROCEDURE: SPIP and TAP Block|PROCEDURE: SPIP Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DOAC in Chinese Patients With Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation|Stroke|Stroke, Acute|Brain Diseases|Major Adverse Cardiovascular Event|Arterial Thromboembolism|Venous Thromboembolism
Interventions: DIAGNOSTIC_TEST: Blood Tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of AMG 531 in Japanese Subjects With ITP
Status: COMPLETED
Conditions: Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)
Interventions: DRUG: Romiplostim (AMG-531)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of an Inhaled Glucocorticosteroid (ICS) on Endothelial Dysfunction in Cigarette Smokers
Status: COMPLETED
Conditions: Tobacco Abuse Smoke
Interventions: DRUG: Fluticasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Study to Evaluate the Effects of Ranibizumab (Lucentis) for Patients With Rubeosis and Neovascular Glaucoma
Status: COMPLETED
Conditions: Neovascular Glaucoma|Rubeosis
Interventions: DRUG: 0.5mg intraocular Ranibizumab (Lucentis)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NASH-FITTER: Nonalcoholic Steatohepatitis Fitness Intervention Treatment Targeting Endothelial Dysfunction Reversal
Status: WITHDRAWN
Conditions: Non-Alcoholic Fatty Liver Disease|Non Alcoholic Steatohepatitis|NASH - Nonalcoholic Steatohepatitis
Interventions: BEHAVIORAL: Moderate intensity aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Synergistic Treatment for Hepatocellular Carcinoma (HCC) Using Transcatheter Arterial Chemoembolization (TACE) With Anti-hepatitis B Virus (Anti-HBV) Therapy
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Transcatheter arterial chemoembolization (TACE)|DRUG: Telbivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Dobutamine on Postoperative Cardiac Function in Aortic Valve Replacement
Status: SUSPENDED
Conditions: Heart Failure
Interventions: DRUG: Dobutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Facial Emotion Recognition in Patients Who Committed Sexual Assault Against Children: an EEG Study
Status: NOT_YET_RECRUITING
Conditions: Child Sexual Abuse|Emotion Recognition
Interventions: OTHER: ROUTINE CARE|DEVICE: Facial emotion stimuli prensentation task with EEG recording and facial emotion recognition task
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Short-course Out-patient Pulmonary Rehabilitation and COPD Exacerbations
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Multimodal Wearable Device-based Study to Evaluate the Efficacy of an Exercise Prescription Intervention in IBD
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Bowel Diseases
Interventions: BEHAVIORAL: Exercise interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring Predictors of Symptoms Relapse After Discontinuation of Treatment in Overactive Bladder (OAB) Patients
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Tolterodine|DRUG: Tolterodine|DRUG: Tolterodine 6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Multifocal Intraocular Lens on Contrast Sensitivity in Primary Angle-Closure Patients
Status: COMPLETED
Conditions: Primary Angle Closure Glaucoma|Primary Angle Glaucoma Closure Suspect|Senile Cataract
Interventions: DIAGNOSTIC_TEST: Contrast sensitivity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plication of the Rectus Abdominis in Two Planes and in One Continuous Suture Plan
Status: COMPLETED
Conditions: Disorder of Abdomen
Interventions: PROCEDURE: Correction of diastasis of the rectus abdominis muscles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A New Intelligent Stocking for Quantification of Edema in the Lower Limbs
Status: RECRUITING
Conditions: Edema Leg
Interventions: DEVICE: Single volume measurement with ESD|DEVICE: Single volume measurement with WDV|DEVICE: Single circumference measurement with tape measure|DEVICE: Continuous volume measurement with ESD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Examining the Impact of a Self-compassion Intervention on Physical Activity Behaviour Among People With Prediabetes
Status: UNKNOWN
Conditions: PreDiabetes
Interventions: BEHAVIORAL: Control Group|BEHAVIORAL: Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hypochlorous Acid Mouthwash, Oral Bacteria, and Staphylococcus Aureus
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: OTHER: La Chlogen mouthwash|OTHER: water|OTHER: La Chlogen mouthwash and La Chlogen periodontal flosser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Remaxol® in Mechanical Jaundice of Non-malignant Origin
Status: COMPLETED
Conditions: Jaundice, Obstructive
Interventions: DRUG: Remaxol (succinate + methionine + inosine + nicotinamide)|DRUG: Ringer's Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Herceptin Followed by Chemotherapy in Treating Women With Metastatic Breast Cancer That Overexpresses HER2
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Herceptin™ (Her)|DRUG: Herceptin™ (Her) + chemo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Tracheal Pressure During CPAP
Status: COMPLETED
Conditions: Continuous Positive Airway Pressure|CPAP Ventilation
Interventions: DEVICE: Evone|DEVICE: Evita Infinity V500
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Focal Muscle Vibration on Bio-psychosocial Outcomes in Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DEVICE: Focal muscle vibration|PROCEDURE: Stretching|PROCEDURE: Strengthening|PROCEDURE: Positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrative Risk Reduction and Treatment for Teen Substance Use Problems and PTSD
Status: COMPLETED
Conditions: PTSD|Alcohol Use Disorders|Substance Use Disorders
Interventions: BEHAVIORAL: Risk Reduction through Family Therapy|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Local Ablative Therapy for Treatment of Oligoprogressive, EGFR-Mutated, Non-Small Cell Lung Cancer After Treatment With Osimertinib
Status: COMPLETED
Conditions: Lung Adenocarcinoma|Lung Neoplasms
Interventions: DRUG: osimertinib|OTHER: Local Ablative Therapy (LAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga-JH04 PET/CT in Patients With Various Types of Cancer
Status: RECRUITING
Conditions: Tumor
Interventions: DRUG: 68Ga-JH04|DRUG: 68Ga-FAPI/18F-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Adjuvant Chemotherapy for Biliary Tract Cancer After Curative Resection
Status: UNKNOWN
Conditions: Cholangiocarcinoma|Gall Bladder Carcinoma
Interventions: DRUG: Gemcitabine|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Corn Oil Plus Vitamin E and B6 on LIpids, PcSk9 and Endothelial Function
Status: UNKNOWN
Conditions: Atherosclerosis
Interventions: OTHER: Vitaminized corn oil|OTHER: Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cranberry for UTI Prevention in Residents of Long Term Care Facilities
Status: COMPLETED
Conditions: Urinary Tract Infection
Interventions: DIETARY_SUPPLEMENT: Once Daily Cranberry Capsule|DIETARY_SUPPLEMENT: Twice Daily Cranberry Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Guided Imagery for Military Sexual Trauma-Related Posttraumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Stress Disorder, Post Traumatic|Military Sexual Trauma
Interventions: BEHAVIORAL: Guided Imagery Audio|BEHAVIORAL: Music Audio
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Pioglitazone in Treating Subjects With Vascular Complications Associated With Type 2 Diabetes Mellitus.
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Pioglitazone and Metformin|DRUG: Glibenclamide and Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Preoperative for Patients Undergoing Laparoscopy for Suspected Appendicitis
Status: COMPLETED
Conditions: Suspected Appendicitis
Interventions: DRUG: dexamethasone phosphate|DRUG: Isotonic NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cisplatin, Irinotecan, and Bevacizumab, in Treating Patients With Small Cell Lung Cancer
Status: COMPLETED
Conditions: Extensive Stage Small Cell Lung Cancer
Interventions: DRUG: cisplatin|DRUG: irinotecan hydrochloride|BIOLOGICAL: bevacizumab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK and Safety Evaluation of Daptomycin in Children Ages 2-6 With Proven or Suspected Gram-positive Infections
Status: COMPLETED
Conditions: Gram Positive Infection|Concurrent Antibiotic Treatment
Interventions: DRUG: daptomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ultrasound Greater Occipital Nerve Block at C2 Level Compared to Landmark-based Greater Occipital Nerve Block
Status: COMPLETED
Conditions: Occipital Neuralgia|Cervicogenic Headache|Migraine Without Aura
Interventions: PROCEDURE: Ultrasound Guided Greater Occipital Nerve Block at C2|PROCEDURE: Landmark-Based Greater Occipital Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of Expanded Designs of a Multifocal IOL
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Tecnis Multifocal Intraocular Lens|DEVICE: Monofocal Intraocular Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Shared Decision-Making for the Promotion of Patient-Centered Imaging in the ED: Suspected Kidney Stones
Status: COMPLETED
Conditions: Shared Decision-making|Kidney Stone|Emergencies|Radiation Exposure|Communication
Interventions: BEHAVIORAL: Decision Aid|OTHER: Standardized Educational Material (informational pamphlet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Implementation of Metformin theraPy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD)
Status: RECRUITING
Conditions: Autosomal Dominant Polycystic Kidney Disease
Interventions: DRUG: Metformin XR|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Healthy Older People Everyday (HOPE) - Role of Healthy Diet on Muscle and Bone Health
Status: UNKNOWN
Conditions: Muscle Weakness|Bone Health|Cognitive Decline
Interventions: OTHER: Protein supplementation and regular physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Dobutamine and Regadenoson Stress Cardiac Magnetic Resonance (MR)
Status: TERMINATED
Conditions: Coronary Artery Disease|Asthma|Chronic Obstructive Pulmonary Disease (COPD)|Angina
Interventions: DRUG: Regadenoson|DRUG: Dobutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy Study of Treatment With Single Doses of CHF 4226 pMDI in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: CHF 4226 pMDI|DRUG: CHF 4226 pMDI|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real-Time Ultrasound-guidance Facilitates Paramedian Spinal Anaesthesia
Status: COMPLETED
Conditions: Wounds and Injuries
Interventions: PROCEDURE: Real-time Ultrasound-guided|PROCEDURE: Anatomical Landmark Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Oslo Sports Trauma Research Center (OSTRC) Injury Prevention Exercises Reducing Injuries Rate Among Athletes.
Status: UNKNOWN
Conditions: Sport Injury
Interventions: OTHER: The Oslo Sports Trauma Research Center (OSTRC) Injury Prevention Program|OTHER: Usual warm up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Retrospective Study Evaluating The Current Utilization Of Desvenlafaxine Succinate Sustained-Release (Pristiq) Among Psychiatrists And Primary Care Physicians In The Treatment Of Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: OTHER: Pristiq first-line treatment charts|OTHER: Pristiq second-line treatment charts|OTHER: SNRI or SSRI first-line treatment charts|OTHER: SNRI or SSRI second-line treatment charts
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of JYB1904 (an Anti-immunoglobulin E Antibody) in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JYB1904|DRUG: Omalizumab|DRUG: JYB1904 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Extension of Tocilizumab in Subjects With Generalized Myasthenia Gravis
Status: RECRUITING
Conditions: Myasthenia Gravis, Generalized
Interventions: DRUG: Tocilizumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FastWire REvascularisation of Extremities, (For LOWer Limbs) - Feasibility Study (FREEFLOW)
Status: COMPLETED
Conditions: Chronic Total Occlusion of Arteries of the Extremities
Interventions: DEVICE: FastWire System Device - Peripheral
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical Trial to Evaluate the Safety, Pharmacokinetics and Efficacy of CW002
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: CW 002|DRUG: CW 002|DRUG: CW 002
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Study of Long-term Baricitinib (LY3009104) Therapy in Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Baricitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy and Safety of a New Additional Treatment With Tislelizumab in Non-Small Cell Lung Cancer (NSCLC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Tislelizumab|DRUG: Cisplatin injection|DRUG: Paclitaxel injection|DRUG: Pemetrexed Disodium|DRUG: Placebos|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Electroacupuncture Compared With Transcutaneous Electric Nerve Stimulation for Functional Constipation
Status: COMPLETED
Conditions: Functional Constipation
Interventions: DEVICE: Electroacupuncture|DEVICE: TranscutaneousElectricNerveStimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Residual Paralysis and Reversal With Routine Neostigmine Versus Half-dose Sugammadex and Routine Neostigmine
Status: COMPLETED
Conditions: Neuromuscular Blockade|Sugammadex|Neostigmine|Complication of Anesthesia|Postoperative Residual Curarization|Rocuronium
Interventions: DRUG: Neostigmine|DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Idelalisib in Adults Receiving Ruxolitinib as Therapy for Primary, Post-Polycythemia Vera, or Post-Essential Thrombocythemia Myelofibrosis With Progressive or Relapsed Disease
Status: TERMINATED
Conditions: Myelofibrosis
Interventions: DRUG: Idelalisib|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EMD for Treatment of Proximal Class-II Furcation Involvements
Status: COMPLETED
Conditions: Generalized Aggressive Periodontitis
Interventions: PROCEDURE: Enamel matrix derivative proteins|PROCEDURE: Open Flap debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block (ESPB): in Patients Undergoing Surgery Through a Flank or Anterior Subcostal Incision.
Status: ENROLLING_BY_INVITATION
Conditions: Nephrectomy|Partial Nephrectomy|Incision Site Discomfort
Interventions: DRUG: Ropivacaine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Follow On Community Testing Study To Evaluate The Performance of the Lucira COVID-19 All-In-One Test Kit
Status: COMPLETED
Conditions: Covid19|Corona Virus Infection
Interventions: DEVICE: Lucira COVID-19 All-In-One test kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of a Chlorine Dioxide Spray on Dental Plaque and Respiratory Pathogens in Institutionalized Elders
Status: COMPLETED
Conditions: Oral Hygiene|Frail Elderly|Nursing Homes|Chlorhexidine
Interventions: OTHER: Oral spray (chlorhexidine spray, chlorine dioxide spray, sterile water spray)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PARASTOP - Paracetamol With Strong Opioids
Status: RECRUITING
Conditions: Cancer Pain|Cancer
Interventions: DRUG: Paracetamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Open-label, LOSARTAN Therapy on the Progression of Aortic Root Dilation in Patients With Marfan Syndrome
Status: UNKNOWN
Conditions: Marfan Syndrome
Interventions: DRUG: Losartan and Atenolol or Propranolol|DRUG: Atenolol or Propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Association Between CytochromeP4501A2 and CytochromeP4502E1 Gene Polymorphisms and Metabolism of Theophylline
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: theophylline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Positron-Emission-Tomography (PET) Study to Measure the Blockade of Dopamine Receptors (D2) in Specific Areas of the Brain in Relation to the Plasma Concentrations of Paliperidone Extended Release (ER) and Oral Risperidone in Schizophrenia Patients and Healthy Controls
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone ER|DRUG: Oral risperidone|OTHER: PET Scan|DRUG: Oral risperidone|DRUG: Oral risperidone|DRUG: Paliperidone ER|DRUG: Paliperidone ER|DRUG: Oral risperidone|DRUG: Paliperidone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Confirmatory Study of MT-2412 in Japanese Patients With Type 2 Diabetes (Add-on Study of Canagliflozin)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Teneligliptin|DRUG: Canagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT