pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy of Estrogen-intrauterine Stent System After Intrauterine Adhesiolysis
Status: RECRUITING
Conditions: Intrauterine Adhesion
Interventions: DEVICE: Estrogen Intrauterine Stent System|DEVICE: Foley balloon combined with self-cross-link sodium hyaluronate gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation in Safety-net Environments (RISE) to Improve Outcomes in Vulnerable Patients With COPD
Status: RECRUITING
Conditions: COPD (Chronic Obstructive Pulmonary Disease)
Interventions: BEHAVIORAL: COPD Wellness|BEHAVIORAL: COPD Wellness Plus+|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: DPBRN Hygienists Internet Quality Improvement in Tobacco Cessation (HiQuit)
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: OTHER: Electronic Referral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short Course Neoadjuvant Chemo-radiotherapy Plus Toripalimab for Locally Advanced Resectble Squamous Cell Carcinoma of Esophagus
Status: RECRUITING
Conditions: Locally Advanced Esophageal Carcinoma
Interventions: DRUG: Neoadjuvant Chemotherapy|DRUG: Neoadjuvant Toripalimab|RADIATION: Short Course Neoadjuvant Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Comparing Carnoy's and GEWF Solutions for Lymph Node Clearing Technique in Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Neoplasms|Neoplasm Metastasis
Interventions: OTHER: Lymph node clearing technique with Carnoy solution|OTHER: Lymph node clearing technique with GEWF solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clamping vs. Free Drainage Before the Removal of Short-term Indwelling Urethral Catheters in Internal Medicine Patients.
Status: TERMINATED
Conditions: Complication of Urinary Catheter
Interventions: PROCEDURE: Clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pre-Emptive Analgesia in Dental Implant Surgery
Status: WITHDRAWN
Conditions: Pain, Postoperative
Interventions: DRUG: Ibuprofen 600 mg|DRUG: Local anesthetic Group 1|DRUG: Placebo oral capsule|DRUG: Local anesthetic Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Specific Manual Approach to the Suboccipital Area on Patients With Chronic Mechanical Neck Pain
Status: UNKNOWN
Conditions: Neck Pain
Interventions: OTHER: translational dorsal glide mobilization technique grade III|OTHER: pressure maintained suboccipital Inhibition technique|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel/Carboplatin Versus Docetaxel/Caelyx in Pretreated Patients With Ovarian Carcinoma
Status: TERMINATED
Conditions: Ovarian Cancer
Interventions: DRUG: Docetaxel|DRUG: Carboplatin|DRUG: Docetaxel|DRUG: Liposomal doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Eluting Stents Versus Bare Metal Stents for Treatment of Symptomatic Extracranial Vertebral Artery Stenosis
Status: COMPLETED
Conditions: Ischemic Stroke|Vertebral Artery Stenosis
Interventions: DEVICE: Drug eluting stent (DES)|DEVICE: Bare metal stent (BES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Physical Activity Intervention in Patients Before Planned Liver Resection for Cancer (APACHE)
Status: COMPLETED
Conditions: Primary Liver Cancer|Secondary Liver Cancer|Liver Metastases
Interventions: BEHAVIORAL: Interval training|OTHER: Standard Oncologic care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Morbidity and Mortality Associated With Dysphagia in Stroke Patients Based on Pharyngeal Residue Severity
Status: UNKNOWN
Conditions: Dysphagia Following Cerebral Infarction
Interventions: PROCEDURE: Fiberoptic endoscopic evaluation of swallowing (FEES)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Inspiratory Muscle Training and Behavioral Support to Alleviate Dyspnea and Promote Walking in Lung Cancer Survivors: A Pilot Study
Status: COMPLETED
Conditions: Lung Neoplasm
Interventions: BEHAVIORAL: Tele-rehabilitation|OTHER: Education only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Amprenavir/Ritonavir, Saquinavir/Ritonavir or Efavirenz in HIV-Infected Subjects Following Failure With Kaletra (ABT-378/Ritonavir) as Their First Protease Inhibitor Based HAART
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Amprenavir/ritonavir|DRUG: Saquinavir/ritonavir|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vatalanib and Everolimus in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Kidney Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: RAD001 (everolimus)|DRUG: PTK787 (vatalanib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Universal CAR-T Cells in Patients With Refractory Autoimmune Diseases of the Nervous System.
Status: NOT_YET_RECRUITING
Conditions: Neuromyelitis Optica Spectrum Disorders|Myasthenia Gravis, Generalized|Multiple Sclerosis|Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Interventions: DRUG: Universal BCMA CAR-T|DRUG: Universal CD19 CAR-T|DRUG: Universal BCMA CAR-T; Universal CD19 CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: KRT-232 in Combination With TL-895 for the Treatment of R/R MF and KRT-232 for the Treatment of JAKi Intolerant MF
Status: RECRUITING
Conditions: Myelofibrosis|Post-PV MF|Post-ET Myelofibrosis|Primary Myelofibrosis
Interventions: DRUG: KRT-232|DRUG: TL-895
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1a/1b Study of STK-012 Monotherapy and in Combination With Pembrolizumab in Patients With Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|Non Small Cell Lung Cancer|Head and Neck Squamous Cell Carcinoma|Malignant Melanoma|Renal Cell Carcinoma|Cervical Cancer|Microsatellite Instability High|Gastric Cancer|GastroEsophageal Cancer|Urothelial Carcinoma|Mismatch Repair Deficiency
Interventions: DRUG: STK-012|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: One Year, Open Label, Dose Escalation Long-term Safety Study in Multiple Sclerosis (MS) Subjects With Spasticity
Status: COMPLETED
Conditions: Multiple Sclerosis|Spasticity
Interventions: DRUG: arbaclofen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OSPREY is a Post-market, Global, Multicentre, Observational, Prospective Registry.
Status: RECRUITING
Conditions: Pancreatic Neoplasm|Digestive System Neoplasm|Neoplasms by Site|Neoplasms|Endocrine Gland Neoplasm|Digestive System Disease|Pancreatic Diseases|Endocrine System Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Residual Insulin Secretion in Patients With Type 1 Diabetes Under a Low Carbohydrate Diet or a Ketogenic Diet
Status: UNKNOWN
Conditions: Type1 Diabetes
Interventions: BEHAVIORAL: Low carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of YH16410 Versus Rosuvastatin and Telmisartan Monotherapies in Patients With Hypertension and Hyperlipidemia
Status: COMPLETED
Conditions: Hyperlipidemia|Hypertension
Interventions: DRUG: YH16410|DRUG: Rosuvastatin|DRUG: Telmisartan|DRUG: YH16410 placebo|DRUG: Rosuvastatin placebo|DRUG: Telmisartan placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety And Tolerability Study Of RN6G In Patients With Dry, Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Age-Related Maculopathy|Age-Related Maculopathies|Eye Diseases|Retinal Degeneration|Macular Degeneration
Interventions: BIOLOGICAL: RN6G|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Feasibility Study Testing a Sleep Intervention in Prostate Cancer Patients With Insomnia
Status: COMPLETED
Conditions: Cancer of Prostate|Insomnia
Interventions: BEHAVIORAL: 12-week aerobic exercise and cognitive-behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Consequences of Doing What Should Not be Done in Primary Care
Status: COMPLETED
Conditions: Overdose|Adverse Event
Interventions: DRUG: Benzodiazepines|DRUG: Non-steroidal anti-inflammatory drugs|DRUG: paracetamol|DRUG: Antimicrobial agent|DRUG: Lipid-lowering drug|DIAGNOSTIC_TEST: Prostate cancer|RADIATION: Lumbago|DRUG: Antimicrobial agent|DRUG: Mucolytic|DRUG: Ibuprofen and paracetamol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I, Open-Label, 2 Part Multicentre Study to Assess the Safety and Efficacy of Olaparib in Combination With Carboplatin in Patients With Advanced HER-2 Negative Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Olaparib|DRUG: Carboplatin|DRUG: Anthracycline|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Fixed Dentures in Head and Neck Cancer (IMFDHAC)
Status: COMPLETED
Conditions: Head and Neck Neoplasms|Dental Prosthesis|Dentures|Quality of Life
Interventions: DEVICE: Fixed prosthodontics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel/Cisplatin/Fluorouracil Followed by Paclitaxel/Cisplatin/Radiotherapy and Esophagectomy for Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: PROCEDURE: TP-HDFL,TP-CCRT, Esophagectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Health Education and Progressive Muscle Relaxation Exercise on Vasomotor Symptoms and Sleep Problems With Perimenopausal Women
Status: COMPLETED
Conditions: Vasomotor Symptoms|Hot Flashes|Sleep Problem
Interventions: BEHAVIORAL: progressive muscle relaxation exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Effectiveness Study of Constant-Load Versus Graded Aerobic Exercise in Obese Children With Bronchial Asthma
Status: COMPLETED
Conditions: Bronchial Asthma
Interventions: OTHER: Constant-load Aerobic Exercise|OTHER: Graded Aerobic exercise|OTHER: Respiratory Re-training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of LCZ696 in Japanese Patients With Chronic Heart Failure and Reduced Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure With Reduced Ejection Fraction (HF-rEF)
Interventions: DRUG: LCZ696|DRUG: Enalapril|DRUG: Placebo to LCZ696|DRUG: Placebo to Enalapril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Manual Lymphatic Drainage
Status: COMPLETED
Conditions: Venous Leg Ulcer|Venous Insufficiency|Lymphatic Disease
Interventions: OTHER: Manual Lymphatic drainage (MLD)|OTHER: Skin Care|OTHER: Exercise|OTHER: Shame Manual Lymphatic drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intradetrusor Triamcinolone Injection in the Management of Interstitial Cystitis/Bladder Pain Syndrome
Status: WITHDRAWN
Conditions: Interstitial Cystitis|Bladder Pain Syndrome
Interventions: PROCEDURE: 40mg Triamcinolone Injections in the Bladder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enteral L Citrulline Supplementation in Preterm Infants - Safety, Efficacy and Dosing
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia|Bronchopulmonary Dysplasia Associated Pulmonary Hypertension|Pulmonary Hypertension|Premature Birth|Chronic Lung Disease of Prematurity
Interventions: DIETARY_SUPPLEMENT: Enteral L-citrulline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery and Heated Chemotherapy for Adrenocortical Carcinoma
Status: COMPLETED
Conditions: Adrenocortical Carcinoma|Peritoneal Carcinomatosis
Interventions: DRUG: Cisplatin|PROCEDURE: Cytoreductive surgery|DRUG: sodium thiosulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methoclopramide for Gastroesophageal Reflux in Premature Infants
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: Metoclopramide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Women With Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: etoposide|DRUG: ifosfamide|DRUG: topotecan hydrochloride|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of Synchrony Between 4 NIV Ventilators
Status: COMPLETED
Conditions: Respiratoy Failure Requiring NIV Treatment
Interventions: DEVICE: V-PAP III ventilator|DEVICE: Stellar 150 ventilator|DEVICE: BiPAP vision ventilator|DEVICE: V60 ventilator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Pediatric FMP2.1/AS02A Trial in Mali
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria
Interventions: BIOLOGICAL: FMP2.1/AS02A|BIOLOGICAL: Rabies vaccine (RabAvert)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Digital Mental Health Care for COVID-19 High-Risk Populations - Phase 2
Status: NOT_YET_RECRUITING
Conditions: Stigma, Social|Help-Seeking Behavior
Interventions: OTHER: Adjusted Content Intervention|OTHER: Non-Adjusted Intervention Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of 3% Minoxidil Lotion for Beard Enhancement
Status: COMPLETED
Conditions: Beard Enhancement
Interventions: DRUG: 3 % Minoxidil lotion|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial Evaluating Control-IQ Technology in Adults With Type 2 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes Treated With Insulin
Interventions: DEVICE: t:slim X2 insulin pump with Control-IQ technology 1.5 and Dexcom G6 CGM|DEVICE: Standard Therapy plus continuous glucose monitoring (CGM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Augmented Reality Intervention on the Range of Motion, Muscle Strength, Function of Upper Extremity and Balance in Children With Spastic Hemiplegic Cerebral Palsy: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Spastic Hemiplegic Cerebral Palsy
Interventions: OTHER: Balance It|OTHER: Bubble Pop|OTHER: Scoop'd
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TD-1792 in Gram-positive Complicated Skin and Skin Structure Infection
Status: COMPLETED
Conditions: Staphylococcal Skin Infection
Interventions: DRUG: TD-1792|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Abdominal Aortic Aneurysm Exclusion (TALENT Abdominal)
Status: UNKNOWN
Conditions: Abdominal Aortic Aneurysm
Interventions: DEVICE: TALENT Enhanced LPS Endoluminal Stent-Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Locally Advanced Head and Neck Cancer Receiving Postoperative Radiotherapy
Status: WITHDRAWN
Conditions: Head and Neck Cancer
Interventions: DRUG: Placebo|DRUG: palifermin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Soy Protein/Effexor Hormone Therapy for Prostate Cancer
Status: TERMINATED
Conditions: Hot Flashes|Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: oral soy protein/isoflavones powder|DRUG: Venlafaxine|DIETARY_SUPPLEMENT: Placebo Powder|DRUG: Placebo Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility of the Combination of Chemotherapy (Carbo/Caelyx or Carbo/Doxorubicin) With Tocilizumab (mAb IL-6R) and Peg-Intron in Patients With Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: Recurrent Ovarian Cancer
Interventions: DRUG: tocilizumab and interferon alpha 2-b|DRUG: Carboplatin and Caelyx or doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atrial Appendage Micrograft Transplants to Assist Heart Repair After Cardiac Surgery
Status: RECRUITING
Conditions: Ischemic Heart Disease|Ischemic Cardiomyopathy|Heart Failure, Systolic|Heart Failure NYHA Class III|Heart Failure NYHA Class II|Heart Failure NYHA Class IV|Coronary Artery Disease
Interventions: PROCEDURE: Epicardial AAMs-patch transplantation|DIAGNOSTIC_TEST: RNA-stabilized whole blood sampling|DIAGNOSTIC_TEST: Plasma sampling|DIAGNOSTIC_TEST: Transthoracic echocardiography|DIAGNOSTIC_TEST: Late-gadolinium enhancement cardiac magnetic resonance imaging (LGE-CMRI)|OTHER: Symptom-scaling|OTHER: 6-minute walking test (6MWT)|DIAGNOSTIC_TEST: Blood sampling (NT-proBNP)|DIAGNOSTIC_TEST: Transesophageal echocardiography|PROCEDURE: Epicardial collagen-based patch transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TReAtmeNt of Small Coronary Vessels: MagicTouch Sirolimus Coated Balloon
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease|DCB
Interventions: DEVICE: sirolimus drug coated balloon (SCB)|DEVICE: paclitaxel releasing coronary balloon catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prophylaxis With Direct-acting Antivirals for Kidney Transplantation From HCV-Infected Donors to Uninfected Recipients
Status: RECRUITING
Conditions: HCV
Interventions: OTHER: Prophylaxis (P2W)|OTHER: Transmit and Treat (T&T)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Subcutaneous (SC) Belimumab in Pediatric Participants With Systemic Lupus Erythematosus (SLE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: COMBINATION_PRODUCT: Belimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of TSR-033 With an Anti-programmed Cell Death-1 Receptor (PD-1) in Participants With Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: TSR-033|DRUG: Dostarlimab|DRUG: mFOLFOX6|DRUG: FOLFIRI|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intravenous Acetaminophen in Patients Undergoing Thoracoscopic Surgery
Status: WITHDRAWN
Conditions: Post-thoracotomy Pain Syndrome
Interventions: DRUG: Ofiramev® (IV Acetaminophen)|DRUG: Placebo IV administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety Study of Fluconazole in Combination With Flucytosine for the Treatment of Early Cryptococcal Infection
Status: TERMINATED
Conditions: Cryptococcal Infection Disseminated
Interventions: DRUG: Flucytosine and fluconazole|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Refractive Results and Patient Satisfaction After Cataract Surgery
Status: UNKNOWN
Conditions: Cataract
Interventions: PROCEDURE: Cataract surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Single Dose of BI 1744 CL in Patients With Mild and Moderate Hepatic Impairment Compared to Subjects With Normal Hepatic Function
Status: COMPLETED
Conditions: Healthy|Liver Diseases
Interventions: DRUG: BI 1744 CL, low dose|DRUG: BI 1744 CL, high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Character Strengths Intervention Among Psychiatrically Hospitalized Youth
Status: COMPLETED
Conditions: Psychiatric Hospitalization|Mental Disorders|Child/Adolescent Problems
Interventions: BEHAVIORAL: Identifying and Using Signature Strengths|BEHAVIORAL: Identifying and Writing Down Coping Skills|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reproducibility of Virtual Exercise Assessments Versus Face-to-face Exercise Testing in Adults With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: PROCEDURE: One-Minute Sit-to-Stand Test|PROCEDURE: Chester Step Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Interactive Cancer Communication System (ICCS) Directed Physical Activity Enhancement for Colon Cancer Survivors
Status: COMPLETED
Conditions: Colon Cancer
Interventions: BEHAVIORAL: Survivorship CHESS|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Technical Modifications of Appendicular Stump Closure During Laparoscopic Appendectomy
Status: COMPLETED
Conditions: Acute Appendicitis
Interventions: PROCEDURE: Stapler appendectomy|PROCEDURE: Endoloop|PROCEDURE: Hem-O-Lock
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Centering Gender Affirming Resources in Higher Education
Status: RECRUITING
Conditions: Sexual Violence|Drinking Heavy
Interventions: BEHAVIORAL: Giving Information for Trauma Support and Safety (GIFTSS) Training|BEHAVIORAL: Centering gender Affirming Resources in higher Education (CARE) Learning Modules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combination Deferasirox and Deferiprone for Severe Iron Overload in Thalassemia
Status: COMPLETED
Conditions: Thalassemia Major With Severe Transfusional Iron Overload
Interventions: DRUG: Deferasirox and deferiprone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin for Preeclampsia Prevention in Pregnant Women With Type 1 Diabetes Mellitus
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1|Pregnancy in Diabetes
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Frequency of Eosinophilic Esophagitis in Patients With Heartburn That is Refractory to Proton Pump Inhibitors
Status: TERMINATED
Conditions: Gastroesophageal Reflux Disease|Eosinophilic Esophagitis
Interventions: DRUG: Treat with lansoprazole 30 mg BID for 2 weeks, endoscopic examination with esophageal biopsy for patients with persistent symptoms
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: oxLDL in Diabetes Mellitus Patients and Disease Periodontal
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus With Periodontal Disease
Interventions: PROCEDURE: Non-surgical periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of PROSTVAC-V (Vaccinia)/TRICOM and PROSTVAC-F (Fowlpox)/TRICOM With GM-CSF in Patients With PSA Progression After Local Therapy for Prostate Cancer
Status: COMPLETED
Conditions: Recurrent Prostate Carcinoma|Stage I Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer|Stage III Prostate Cancer
Interventions: DRUG: Bicalutamide|DRUG: Goserelin Acetate|BIOLOGICAL: Recombinant Fowlpox-PSA(L155)/TRICOM Vaccine|BIOLOGICAL: Recombinant Vaccinia-TRICOM Vaccine|BIOLOGICAL: Sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food Literacy and Physical Activity Intervention to Optimize Metabolic Health Among Women in Urban Uganda
Status: COMPLETED
Conditions: Abdominal Obesity
Interventions: BEHAVIORAL: Food literacy and physical activity promotion interactive group sessions + Developed health promotion intervention materials (booklet)|BEHAVIORAL: Developed health promotion intervention materials (booklet).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Single Dose of 1% Tropicamide and 10% Phenylephrine for Pupillary Dilation
Status: COMPLETED
Conditions: Eye Diseases
Interventions: DRUG: 1% tropicamide and 10% phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigational Trial to Evaluate Safety and Tolerability of Treprostinil in Children Diagnosed With PAH
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: preservative-free parenteral treprostinil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 131-I-TM-601 Study in Adults With Solid Tumors
Status: COMPLETED
Conditions: Breast Cancer|Non-Small Cell Lung Cancer|Melanoma|Colorectal Cancer|Pancreatic Cancer|Prostate Adenocarcinoma|Glioma|Primary Solid Tumors
Interventions: DRUG: 131-I-TM-601 (chlorotoxin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Thymosin Beta 4 Eye Drops vs. Vehicle in the Treatment of Severe Dry Eye
Status: COMPLETED
Conditions: Dry Eye|Sjogren's Syndrome|Graft vs. Host Disease
Interventions: DRUG: Thymosin Beta 4 eye drops|DRUG: Vehicle Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Incobotulinum Toxin A (Xeomin®) for Troublesome Sialorrhea in Parkinson's Disease (PD)/Parkinsonism
Status: COMPLETED
Conditions: Sialorrhea
Interventions: DRUG: Incobotulinum Toxin A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Effects of Hydroxychloroquine
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Hydroxychloroquine|OTHER: Hydroxychloroquine Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Influence of Nocturnal Food Intake in Eating Behavior of Night Workers
Status: COMPLETED
Conditions: Shift Work Type Circadian Rhythm Sleep Disorder
Interventions: OTHER: With Meal during night work|OTHER: Without Meal during night work|OTHER: Sleep night
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Enhancing Cognitive Control in Mild Cognitive Impairment Via Non-invasive Brain Stimulation
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: Transcranial alternating current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Efficacy of Oral-B New Product Sensi-Stop on Dentinal Hypersensitivity
Status: COMPLETED
Conditions: Tooth Sensitivity
Interventions: DEVICE: Prof applied oxalate|DEVICE: Self applied oxalate|DEVICE: Prof applied placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Central Nervous System Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|DRUG: carmustine|DRUG: cytarabine|DRUG: etoposide|DRUG: melphalan|DRUG: methotrexate|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Investigation on the Effect of Carnitine Supplement on Gut Microbiota and TMAO Production Capacity
Status: COMPLETED
Conditions: Dietary Exposure
Interventions: DIETARY_SUPPLEMENT: L-carnitine supplementation (500 mg per tablet per day, purchased from GNC company)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study in Patients With Atopic Eczema to Test How Effective BI 655130 is and How Well it is Tolerated
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: BI 655130|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Efficacy and Safety of Zolpidem Modified Release Formulation Versus Zolpidem in Insomnia Patients
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders|Primary Insomnia
Interventions: DRUG: Zolpidem MR|DRUG: Zolpidem IR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cellular Immuno-Therapy for COVID-19 Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Covid19
Interventions: BIOLOGICAL: Mesenchymal Stromal Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Evaluating Surufatinib Efficacy and Safety in Biliary Tract Carcinoma Patients
Status: UNKNOWN
Conditions: Biliary Tract Cancer
Interventions: DRUG: Surufatinib|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Time to Treatment and Disease-free Survival of Patients With High-risk Head-neck Cutaneous Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Squamous Cell|Skin Cancer|Carcinoma, Squamous Cell, Skin|Carcinoma, Squamous Cell of Head and Neck|Recurrence|Metastasis
Interventions: OTHER: Treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: New Hypo-Osmolar ORS (Recommended by WHO) for Routine Use in the Diarrhea Management- Surveillance Study for Adverse Effects
Status: COMPLETED
Conditions: Diarrhea|Dysentery
Interventions: DRUG: Hypo-osmolar ORS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EQQUAL-NM for the Promotion of Smoking Cessation in Sexual and Gender Minority Young Adults in New Mexico
Status: NOT_YET_RECRUITING
Conditions: Cigarette Smoking-Related Carcinoma
Interventions: BEHAVIORAL: Smartphone App-delivered Smoking Cessation Intervention|BEHAVIORAL: Smartphone App-delivered Smoking Cessation Intervention|OTHER: Health Promotion and Education|OTHER: Health Promotion and Education|OTHER: Biospecimen Collection|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: MesenchYmal STROMAL CELL Therapy in Patients With Chronic Myocardial Ischemia (MyStromalCell Trial)
Status: COMPLETED
Conditions: Chronic Ischemic Heart Disease
Interventions: BIOLOGICAL: MSC|BIOLOGICAL: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hybrid Versus Cemented TKA Using the NexGen LPS Prosthesis
Status: ACTIVE_NOT_RECRUITING
Conditions: Total Knee Arthroplasty
Interventions: PROCEDURE: Total knee arthroplasty|DEVICE: NEXGEN LPS total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Post-Surgical Symptoms: Gastric Sleeve With and Without Omentopexy "Comparing Post-Surgical Symptoms: Gastric Sleeve With and Without Omentopexy" Comparison of Postoperative Symptoms: Gastric Sleeve With and Without Omentopexy.
Status: COMPLETED
Conditions: Surgical Procedure, Unspecified
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of SynPhNe Physio-neuro Platform on Hand Motor Function Rehabilitation of Acute and Subacute Stroke Patients
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: SynPhNe physio-neuro platform
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Repeated Amiodarone Dosing Regimen Versus Standard Dosing Regimen in Atrial Fibrillation Patient With Rapid Ventricular Response
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: Amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Em-power: Maximizing Functional Independence for Children With Severe Cerebral Palsy
Status: NOT_YET_RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: Power wheelchair skills training using the IndieTrainer system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Hesperidin Therapy on COVID-19 Symptoms (HESPERIDIN)
Status: COMPLETED
Conditions: Covid19|Anosmia|Fever|Cough|Shortness of Breath|Sore Throat|Nausea|Vomiting|Headache|Muscle Weakness|Pain, Muscle|Pain, Chest|Pain, Joint|Pain, Abdominal|Pain|Irritable Mood|Confusion
Interventions: DRUG: Hesperidin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Neurodegenerative Diseases
Status: WITHDRAWN
Conditions: Mild Cognitive Impairment (MCI)|Alzheimer Disease (AD)|Dementia With Lewy Bodies (DLB)|Frontotemporal Lobar Degeneration (FTLD)|Parkinsons Disease With Dementia (PDD)|Transient Epileptic Amnesia (TEA)|Temporal Lobe Epilepsy (TLE)|Spinocerebellar Ataxias (SCA)|HIV Associated Neurocognitive Disorder (HAND)|Amyotrophic Lateral Sclerosis (ALS)|Primary Lateral Sclerosis (PLS)
Interventions: OTHER: Neuraceq
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Allogenic Islet Cell Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Allogenic islet cells (human, U. Chicago)|PROCEDURE: Intraportal infusion of islet cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Investigate the Dermal and Ocular Tolerance of a Developmental Cosmetic Facial Serum Formulation in Healthy Females With Sensitive Skin
Status: COMPLETED
Conditions: Skin Care
Interventions: OTHER: Developmental Serum|OTHER: Physiogel Calming Relief Anti-Redness Serum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Parasternal Blockade and Serum Lactate in Cardiac Surgery
Status: RECRUITING
Conditions: Elective Cardiac Surgery
Interventions: PROCEDURE: Parasternal block|PROCEDURE: Requirement of total dose regarding fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of Fish Oils to Prevent Atrial Mechanical Stunning and Atrial Remodeling Due to Atrial Arrhythmia
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DRUG: Fish oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nudge to Drive Transitions of Care
Status: COMPLETED
Conditions: Preeclampsia|Preeclampsia Severe|Gestational Hypertension|Hypertensive Disorder of Pregnancy|Superimposed Pre-Eclampsia
Interventions: BEHAVIORAL: Nudge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Randomised, Double Blind, Placebo and Active Controlled, Double Dummy,Parallel Group Study to Determine the Safety and Efficacy of Oxycodone/Naloxone Prolonged Release Tablets in Subjects With Moderate to Severe, Chronic Nonmalignant Pain
Status: COMPLETED
Conditions: Subjects With Moderate to Severe, Chronic Nonmalignant Pain
Interventions: DRUG: Oxycodone & naloxone combination, prolonged release|DRUG: placebo oxycodone / naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: An In-vitro Real-time System Based on Tissue Smears to Identify Malignancy During Hysteroscopic Procedure
Status: UNKNOWN
Conditions: Uterine Cervical Neoplasm|Uterine Neoplasms
Interventions: PROCEDURE: Hysteroscopy|DEVICE: Infrared Spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tiotropium+Olodaterol Fixed Dose Combination (FDC) in Chronic Obstructive Pulmonary Disease (OTEMTO 2)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: olodaterol|DRUG: tiotropium|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Imiquimod and Pembrolizumab in Treating Patients With Stage IIIB-IV Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Melanoma|Stage IIIB Cutaneous Melanoma AJCC v7|Stage IIIC Cutaneous Melanoma AJCC v7|Stage IV Cutaneous Melanoma AJCC v6 and v7
Interventions: DRUG: Imiquimod|PROCEDURE: Biopsy|BIOLOGICAL: Pembrolizumab|PROCEDURE: Computed Tomography|PROCEDURE: Positron Emission Tomography|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Rabeprazole on the Pharmacokinetics of Vadadustat
Status: COMPLETED
Conditions: Drug Interaction Potentiation|Pharmacokinetics
Interventions: DRUG: Vadadustat|DRUG: Rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Insulin Efsitora Alfa (LY3209590) Compared to Glargine in Adult Participants With Type 2 Diabetes Who Are Starting Basal Insulin for the First Time (QWINT-1)
Status: COMPLETED
Conditions: Type 2 Diabetes|T2D
Interventions: DRUG: Insulin Efsitora Alfa|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Naltrexone on Nocturnal Breathing Patterns at Altitude
Status: COMPLETED
Conditions: Altitude|Sleep Apnea, Central
Interventions: DRUG: Naltrexone Pill|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Trial of EP4 Receptor Antagonist, AAT-007 (RQ-07; CJ-023,423) in Advanced Solid Tumors
Status: WITHDRAWN
Conditions: Prostate Cancer|Non-Small Cell Lung Cancer|Breast Cancer
Interventions: DRUG: RQ-00000007|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Exercise Therapy and Self-management Support for Patients With Multimorbidity
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Osteoarthritis, Hip|Heart Failure|Coronary Heart Disease|Hypertension|Type2 Diabetes|Chronic Obstructive Pulmonary Disease|Depression
Interventions: BEHAVIORAL: Personalized exercise therapy and self-management support program|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Intervention and Assessment of Obesity-related Gene Methylation Levels in Overweight Women
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Dietary folate and hazelnut oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Patient-Centered Adherence Intervention After Acute Coronary Syndrome (ACS) Hospitalization
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: BEHAVIORAL: Intervention|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Correlation of Peritoneal Fluid CA-125 Levels With Postoperative Tumor Histology
Status: COMPLETED
Conditions: Endometrial Carcinoma
Interventions: DIAGNOSTIC_TEST: abdominal fluid CA-125 levels test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ganciclovir/Valganciclovir for Prevention of CMV Reactivation in Acute Injury of the Lung and Respiratory Failure
Status: COMPLETED
Conditions: Acute Lung Injury|Acute Respiratory Distress Syndrome|Respiratory Failure
Interventions: DRUG: IV Ganciclovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Blood Flow Restriction in Improving Muscle Strength of Patients With Hemophilic Knee Arthropathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemophilia
Interventions: OTHER: Blood flow restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Home-based vs. Clinic-based Rehabilitation on Sensorimotor, Cognition, Daily Function, and Participation
Status: COMPLETED
Conditions: Chronic Stroke
Interventions: BEHAVIORAL: bilateral training with and without mirror feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT