pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Phase Ib/II Study Of JS015 Combination Therapy in Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: JS015|BIOLOGICAL: Toripalimab|BIOLOGICAL: Paclitaxel|DRUG: Irinotecan|DRUG: Capecitabine|DRUG: Oxaliplatin|BIOLOGICAL: Bevacizumab|DRUG: Fluorouracil|DRUG: Leucovorin|DRUG: Gemcitabine|DRUG: Albumin-Bound Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Effectiveness of Acupuncture as a Treatment in Patients Diagnosed With CFS.
Status: UNKNOWN
Conditions: Chronic Fatigue Syndrome.|Muscular Diseases.|Cognitive Impairment|Sleep Disturbances|Pain.
Interventions: DEVICE: Acupuncture.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PRINT Trial (Platelet Rich Injection vs Needle Tenotomy)
Status: UNKNOWN
Conditions: Lateral Epicondylitis|Tendinosis|Elbow, Tennis|Elbows Tendonitis
Interventions: PROCEDURE: Percutaneous Needle Tenotomy|PROCEDURE: PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Validation of a Mobile Phone Based on EPRO Tool in Subjects With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: SLE|Lupus Erythematosus, Systemic|Systemic Lupus Erythematosus
Interventions: OTHER: No Medical Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ErythroPOietin Alfa to Prevent Mortality and Reduce Severe Disability in Critically Ill TRAUMA Patients
Status: RECRUITING
Conditions: Trauma|Traumatic Injury|Traumatic Brain Injury|Wounds and Injuries|Penetrating Injury|Blunt Injury|Major Trauma|Multiple Trauma
Interventions: DRUG: Epoetin Alfa 40000 UNT/ML|DRUG: Sodium Chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Estrogen-progestin Therapy in Continuous Regimen Versus Combination Estrogen-progestin Therapy in Continuous Regimen Plus Levonorgestrel-releasing Intrauterine System (LNG-IUS)
Status: UNKNOWN
Conditions: Adenomyosis|Chronic Pelvic Pain
Interventions: DRUG: LNG-IUS 13,5 mg Levonorgestrel|DRUG: Levonorgestrel 0,10 mg+ ethinylestradiol 0,02 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Covered Metallic Stents for First-Line Treatment of Benign Bile Duct Strictures
Status: COMPLETED
Conditions: Common Bile Duct Stricture
Interventions: DEVICE: Fully covered Metallic Stent|DEVICE: Plastic Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Resveratrol in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Trans-resveratrol extract from Polygonum Cuspidatum|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of MBP8298 in Subjects With Secondary Progressive Multiple Sclerosis
Status: TERMINATED
Conditions: Multiple Sclerosis, Secondary Progressive
Interventions: DRUG: MBP8298
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tabetri on Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: Tabetri capsule|DIETARY_SUPPLEMENT: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dexmedetomidine in TAP Block for Inguinal Hernia Repair
Status: UNKNOWN
Conditions: Inguinal Hernia|Analgesia|Pain, Acute|Pain, Chronic|Pain, Neuropathic
Interventions: OTHER: local anesthetic and dexmedetomidine|OTHER: local anesthetic and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Stimulator of the Salivary Vibration of the Parotid Glands
Status: COMPLETED
Conditions: Saliva Stimulated
Interventions: DEVICE: PHYSICAL VIBRATION OF THE PAROTID GLANDS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MBM-01 (Tempol) for the Treatment of Ataxia Telangiectasia
Status: UNKNOWN
Conditions: Ataxia Telangiectasia Louis-Bar|Ataxia Telangiectasia in Children|Ataxia Telangiectasia
Interventions: DRUG: MBM-01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension of EMDR vs. PC For Motor Vehicle Accident Trauma
Status: UNKNOWN
Conditions: Trauma, Psychological|Motor Vehicle Accident
Interventions: BEHAVIORAL: EMDR-based Flash technique|BEHAVIORAL: PC-based Flash technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine for Prevention of Bird Flu
Status: COMPLETED
Conditions: Influenza, Human
Interventions: DRUG: Monovalent Influenza Subunit Virion (H5N1) Vaccine, A/Indonesia/05/2005|DRUG: VRC-AViDNA036-00-VP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: EXTEND Exercise Trial
Status: COMPLETED
Conditions: Non-metastatic, Hormone naïve Prostate Cancer
Interventions: DRUG: Enzalutamide|DRUG: Androgen deprivation therapy|BEHAVIORAL: Supervised exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of a Food is Medicine Community Health Worker Program for Pregnant Women
Status: RECRUITING
Conditions: Pre-Eclampsia|Obesity|Gestational Diabetes|Gestational Hypertension
Interventions: OTHER: Women's Health Delaware Food Farmacy|OTHER: Usual Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low VW Activity in Adolescent HMB
Status: ACTIVE_NOT_RECRUITING
Conditions: Von Willebrand Factor Deficiency
Interventions: OTHER: Genetic Analysis|OTHER: Medical Record Data Abstraction|OTHER: Pictorial Blood Assessment Chart (PBAC) score|OTHER: Complete Bleeding Symptom ISTH Bleeding Assessment Tool
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bosentan in Patients With Inoperable Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: bosentan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Exablate Model 4000 Type 1.0/1.1 Following the Treatment of Neuropathic Pain
Status: COMPLETED
Conditions: Peripheral Neuropathy|Neuropathic Pain
Interventions: DEVICE: Exablate treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of X0002 Spray in Subjects With Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: X0002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ventricular Tachycardia Ablation Strategies in Patients With Ischemic Cardiomyopathy
Status: WITHDRAWN
Conditions: Ventricular Tachycardia
Interventions: PROCEDURE: Endocardial ablation|PROCEDURE: Endocardial- Epicardial ablation|DRUG: Antiarrhythmic medications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Adductor Canal Catheter and Intraarticular Catheter Following Primary Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Acute Pain|Regional Anesthesia Morbidity
Interventions: PROCEDURE: Adductor Canal Catheter|PROCEDURE: Intraarticular Catheter|DRUG: Ropivicaine|DRUG: Bupivicaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Probiotics and Health-related Quality of Life in Individuals With Seasonal Allergies
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Probiotic mixture|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pilot Study of Pre- and Post-surgery Chemotherapy With mFOLFIRINOX in Localized, Resectable Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: 5 Fluorouracil|DRUG: Leucovorin|DRUG: Irinotecan|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Inactivity and Insulin Resistance in Skeletal Muscle.
Status: WITHDRAWN
Conditions: Metabolic Syndrome X|Insulin Resistance|Hypertension|Hypercholesterolemia|Obesity
Interventions: BEHAVIORAL: Exercise|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Reduced Dasatinib (70 mg Daily) as First-line Treatment for Newly Diagnosed CML-CP
Status: UNKNOWN
Conditions: Dasatinib|BCR-ABL|Chronic Myeloid Leukemia
Interventions: DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FT596 With Rituximab as Relapse Prevention After Autologous HSCT for NHL
Status: COMPLETED
Conditions: NHL|Non Hodgkin Lymphoma|Diffuse Large B Cell Lymphoma|High-grade B-cell Lymphoma
Interventions: DRUG: FT596|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Preoperative Injection of Mitomycin-C vs. Intraoperative Injection of Mitomycin-C vs. Topical Application of Mitomycin-C (Conventional Use) in Trabeculectomy
Status: TERMINATED
Conditions: Glaucoma Open-Angle Primary|Glaucoma|Open Angle Glaucoma|Glaucoma, Open-Angle
Interventions: DRUG: Mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Continuous Quadratus Lumborum Block Versus Continuous Paravertebral Block In Radical Cystectomy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: US guided Quadratus Lumborum block|PROCEDURE: US guided Paravertebral block.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electrophysiology of Brain Activity During Electrode Implantation in Patients Treated With Deep Brain Stimulation
Status: UNKNOWN
Conditions: Parkinson Disease|Obsessive-Compulsive Disorder|Epilepsy|Depression
Interventions: OTHER: electrophysiological data from DBS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of a 6% Hydrogen Peroxide Tooth Bleaching Agent
Status: COMPLETED
Conditions: Tooth Bleaching
Interventions: OTHER: 6% hydrogen peroxide|OTHER: 35% hydrogen peroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Cryotherapy's Analgesic Impact in Anti-aromatase-induced Arthralgia
Status: RECRUITING
Conditions: Breast Cancer|Aromatase Inhibitors
Interventions: OTHER: Whole-body cryotherapy|OTHER: Placebo cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mini-pool Intravenous Immunoglobulin (MP-IVIG) in Guillain-Barré Syndrome
Status: UNKNOWN
Conditions: Guillain-Barre Syndrome
Interventions: OTHER: Mini-pool Intravenous Immunoglobulin (MP-IVIG)|OTHER: plasma exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peritonitis Prevention After Insertion of Peritoneal Dialysis Catheter.
Status: RECRUITING
Conditions: Peritoneal Dialysis-associated Peritonitis|Peritoneal Dialysis Catheter Infection|Peritoneal Dialysis Complication
Interventions: DRUG: Cefazolin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of TAK-438 Compared to AG-1749 (Lansoprazole) in the Treatment of Gastric Ulcer
Status: COMPLETED
Conditions: Gastric Ulcer
Interventions: DRUG: TAK-438|DRUG: Placebo|DRUG: Lansoprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Prolonged Exposure Therapy Versus Clinical Standard to Reduce Posttraumatic Stress Post Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries|PTSD|Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: Brief Prolonged Exposure Therapy|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brief Mindfulness and Nutrition-Based Interventions for Chronic Pain: Strategies to Ease Pain
Status: WITHDRAWN
Conditions: Opioid Use|Chronic Pain
Interventions: BEHAVIORAL: Brief Mindfulness-Based Intervention (BMBI)|BEHAVIORAL: Control/Nutrition Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep as a Model to Understand and Manipulate Cortical Activity in Order to Promote Functional Recovery After Stroke
Status: COMPLETED
Conditions: Hemispatial Neglect
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS)|DEVICE: Transcranial Alternating Current Stimulation (tACS)|DEVICE: sham Transcranial Magnetic Stimulation (TMS)|DEVICE: sham Transcranial Alternating Current Stimulation (tACS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetics and Pharmacodynamics of Biologic Drugs in Obese Patients With Arthritis
Status: NOT_YET_RECRUITING
Conditions: Juvenile Idiopathic Arthritis|Rheumatoid Arthritis|Obesity
Interventions: DRUG: Etanercept Optimal dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase I Study of Nilontinib and Cetuximab in Patients With Solid Tumors
Status: TERMINATED
Conditions: Colorectal Cancer|Head and Neck Cancer
Interventions: DRUG: Nilotinib + Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Race and Preference for Knee Replacement: A Patient-Centered Intervention
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BEHAVIORAL: DA/MI Intervention|BEHAVIORAL: an educational program (an NIH-developed booklet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nature-Based Sound Application For Hemodialysis Patients
Status: COMPLETED
Conditions: Chronic Kidney Failure|Hemodialysis Patients|Fatigue|Patient Comfort|Nature Sounds
Interventions: OTHER: Nature sound listening|OTHER: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PK/PD of Oral and Vaporized Delta-9-Tetrahydrocannabinol (THC) in Older Adults
Status: RECRUITING
Conditions: Pain, Tolerance|Oral vs Vaporized THC|Abuse Liability
Interventions: DRUG: Dronabinol 5 MG|DRUG: Dronabinol 10 MG|DRUG: 2mg Purified THC in an ethanolic solution|DRUG: 4mg Purified THC in an ethanolic solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Perianal Abscess Recurrence and Fistula Formation: Antibiotics Following Incision and Drainage Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Perianal Abscess|Perianal Fistula
Interventions: DRUG: Antibiotic 1 arm (amoxicillin + clavulanic acid)|DRUG: Antibiotic 2 arm (ciprofloxacin + metronidazole)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Test the Benefit of Vitamin B5 in Patients With Melanoma
Status: RECRUITING
Conditions: Melanoma (Skin)
Interventions: DIETARY_SUPPLEMENT: C-PAN|BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-based HIFST for Older Adults to Prevent Functional Decline
Status: COMPLETED
Conditions: Mobility Limitation|Fall Injury|Slip and Fall
Interventions: BEHAVIORAL: high-intensity functional strength training|BEHAVIORAL: Lower extremity stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Tricuspid Valve Percutaneous Repair System in the Treatment of Severe Secondary Tricuspid Disorders
Status: COMPLETED
Conditions: Tricuspid Regurgitation
Interventions: PROCEDURE: Tricuspid valve|OTHER: Best medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Sunflower Seed Oil Massage on Neonatal Mortality and Morbidity in Nepal
Status: COMPLETED
Conditions: Neonatal Mortality|Neonatal Sepsis
Interventions: OTHER: Sunflower seed oil|OTHER: Mustard seed oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Two Ways of Applying Homework Assignments in the Treatment of Adjustment Disorders
Status: COMPLETED
Conditions: Adjustment Disorders
Interventions: BEHAVIORAL: Cognitive Behavioral Treatment approach supported by virtual reality and positive psychology strategies.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative subQ Pain Control for Spinal Fusion Surgery
Status: COMPLETED
Conditions: Spine Fusion|Surgery|Pain, Postoperative
Interventions: DRUG: 0.25% Marcaine at 2ml/hr and pain medications|DEVICE: Placement of OnQ Drug pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evolution of Oropharyngeal and Rectal Microbiota After Severe Traumatic Brain Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Traumatic Brain Injury|Multiple Trauma
Interventions: PROCEDURE: Oropharyngeal swab|PROCEDURE: Rectal swab|PROCEDURE: Disability rating scale (DRS-F)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 1 Study to Investigate OD-07656 in Healthy Adult Participants
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases|Blau Syndrome|Crohn Disease|Ulcerative Colitis|Spondyloarthritis
Interventions: DRUG: OD-07656
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Efficacy of Sacral Erector Spinae Plane Block for Postoperative Analgesia in Pediatric Rectal Biopsies
Status: COMPLETED
Conditions: Analgesia|Pain, Acute
Interventions: PROCEDURE: Sacral Erector Spinae Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Diaphragmatic Stimulation and Inspiratory Muscle Training in Patients With COPD Exacerbated
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Transcutaneous electrical diaphragmatic stimulation (TEDS)|OTHER: Inspiratory Muscle Training (IMT)|OTHER: Conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Teeth Extraction on Inflammation Marker's Levels in Patients Who Undergoing Cardiac Surgery
Status: UNKNOWN
Conditions: Inflammation Gum|Cardiac Surgery
Interventions: PROCEDURE: Tooth extractions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Huaier Granule in Combination With Nilaparil in Therapy Patients With Stage III/IV BRCA Wild-type Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Huaier granule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Insulin Intensification Therapies in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Lispro Premix|DRUG: Insulin Glargine|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Iron vs. Oral Iron Supplementation for Postpartum Anemia
Status: COMPLETED
Conditions: Anemia, Iron Deficiency|Delivery Complication
Interventions: DRUG: Ferrous sulfate|DRUG: Iron dextran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ß-Cell Function and Glycemic Control in Newly Diagnosed Type 2 Diabetic Patients With Moderate Hyperglycemia
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DRUG: Insulin|DRUG: Metformin|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tacrolimus Versus Mycophenolate for Autoimmune Hepatitis Patients With Incomplete Response on First Line Therapy
Status: UNKNOWN
Conditions: Autoimmune Hepatitis
Interventions: DRUG: Mycophenolate Mofetil|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Narrative Writing Duration and Post-writing Processing Instructions on PTSD
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: BEHAVIORAL: Narrative Writing: Trauma-Assigned|BEHAVIORAL: Narrative Writing: Trauma-Spontaneous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Telerehabilitation-Based Motor Imagery Training on Pain in People With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Pain
Interventions: BEHAVIORAL: Telerehabilitation-based motor imagery training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Neuromuscular Electrical Stimulation on Critically Ill Patients With Mechanical Ventilation
Status: UNKNOWN
Conditions: Respiratory Insufficiency Requiring Mechanical Ventilation
Interventions: BEHAVIORAL: Neuromuscular Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bimatoprost 0.03% Versus Travoprost 0.004% in Patients Currently on Latanoprost 0.005%
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: bimatoprost 0.03% eye drops|DRUG: travoprost 0.004% eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does Dapagliflozin Regress Left Ventricular Hypertrophy In Patients With Type 2 Diabetes?
Status: COMPLETED
Conditions: Type 2 Diabetes|Left Ventricular Hypertrophy
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Range Evaluation of Norovirus Challenge Pool (GII.4, CIN-1)
Status: COMPLETED
Conditions: Norovirus Infections
Interventions: BIOLOGICAL: Norovirus challenge pool (GII.4, CIN-1)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Feasibility Aquatic Physical Exercise to Reduce Falls in Institutionalized Elderly
Status: COMPLETED
Conditions: Age Problems|Cognitive Impairment|Elderly|Postural Balance|Strength
Interventions: OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ruxolitinib in Combination With Nilotinib in Patients With Chronic Phase CML
Status: WITHDRAWN
Conditions: Leukemia, Chronic Myeloid
Interventions: DRUG: Nilotinib|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Safety Study of Buprenorphine (CAM2038) in Adult Outpatients With Opioid Use Disorder
Status: COMPLETED
Conditions: Opioid Use Disorder
Interventions: DRUG: CAM2038 q1w or q4w exposure to SL BPN/NX|DRUG: CAM2038 q1w or q4w new to BPN treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adherence to Treatment, Safety and Tolerability Study of the Medical Information Device #1 (MIND1) in Subjects With Schizophrenia or Bipolar I Disorder
Status: WITHDRAWN
Conditions: Bipolar 1 Disorder|Schizophrenia|Mental Disorder|Nervous System Diseases
Interventions: DRUG: Aripiprazole|DEVICE: Ingestible Event Marker (IEM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intramuscular Dexmedetomidine as Premedication
Status: UNKNOWN
Conditions: Laryngoscopy|Preanesthetic Medication
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acceptability and Feasibility of Combination Treatment for Cervical Precancer Among South African Women Living With HIV
Status: RECRUITING
Conditions: Cervical Cancer|CIN2|CIN3|Human Immunodeficiency Virus|Human Papillomavirus
Interventions: DRUG: 5 Fluorouracil (5 FU) Cream|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Multiple Dose Study of PF-04950615 (RN316) in Subjects on High Doses of Statins
Status: COMPLETED
Conditions: Hypercholesterolemia|Dyslipidemia
Interventions: BIOLOGICAL: Placebo|DRUG: Statin|BIOLOGICAL: PF-04950615 (RN316)|DRUG: Statin|BIOLOGICAL: PF-04950615 (RN316)|DRUG: Statin|BIOLOGICAL: PF-04950615 (RN316)|DRUG: Satin|BIOLOGICAL: PF-04950615 (RN316)|DRUG: Statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DANISH.MRD: Danish Assessment of Minimal Residual Disease by Liquid Biopsies
Status: RECRUITING
Conditions: Colorectal Neoplasms|Colorectal Cancer|Colorectal Adenocarcinoma|Colorectal Cancer Stage I|Colorectal Cancer Stage II|Colorectal Cancer Stage III
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Laser Therapy for Diabetic Peripheral Neuropathic Pain
Status: WITHDRAWN
Conditions: Diabetic Peripheral Neuropathy
Interventions: DEVICE: Laser treatment|DEVICE: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Laparoscopic Non Anatomical Liver Resection in Hepatic Pathology
Status: NOT_YET_RECRUITING
Conditions: Laparoscopic Liver Resection
Interventions: PROCEDURE: Laparoscopic liver resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Single Dose Administration of GR2002 Injection in Chinese Health Volunteers
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: GR2002 injection|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nitrous Oxide Treatment for Tinnitus
Status: COMPLETED
Conditions: Tinnitus
Interventions: DRUG: Nitrous oxide gas for inhalation|DRUG: Placebo gas for inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Mixed-Method Evaluation of the Impact of Social Risk Screening on Uptake of Social Assistance
Status: COMPLETED
Conditions: Low-income Populations|Social Determinants of Health
Interventions: BEHAVIORAL: Social Risk Screening Tool|OTHER: Electronic Resource Map
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PILONIDAL SINUS: CONVENTIONAL CARE VERSUS NEGATIVE PRESSURE THERAPY.
Status: UNKNOWN
Conditions: Pilonidal Sinus|Wound Heal
Interventions: DEVICE: Negative pressure therapy|OTHER: Conventional wound care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protein Balance in Protein Supplemented Elderly Patients: Acute Study With Protein-tracer-techniques
Status: WITHDRAWN
Conditions: Elderly
Interventions: DIETARY_SUPPLEMENT: Whey protein high in leucin|DIETARY_SUPPLEMENT: Whey protein normal in leucin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comprehensive Study of Clinically Staged Pediatric Hodgkin's Disease: Chemotherapy for All Patients; Supplementary Low Dose Involved Field Irradiation for Selected Patients (CCG 5942)
Status: COMPLETED
Conditions: Pediatric|Hodgkin's Disease
Interventions: DRUG: COPP/ABV|DRUG: COPP/ABV|DRUG: intensive chemo with concurrent growth factor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral TGF-beta Receptor I Inhibitor Vactosertib in SOC Chemoradiotherapy for Esophageal Adenocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Adenocarcinoma Esophagus|Locally Advanced Adenocarcinoma|Siewert Type I Adenocarcinoma of Esophagogastric Junction|Siewert Type II Adenocarcinoma of Esophagogastric Junction
Interventions: DRUG: Vactosertib|DRUG: Standard of Care Chemotherapy|RADIATION: Concurrent Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Triggers in Double Ovarian Stimulation (DuoStim).
Status: UNKNOWN
Conditions: IVF|LOW OVARIAN RESPONSE
Interventions: DRUG: Triptorelin acetate (a-GnRH)|DRUG: Ovitrelle® (hCG)|DRUG: Decapeptyl 0.1 mg® (a-GnRH) and Ovitrelle® (hCG) used together
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Extensive Clinical Target Volumes in Postoperative Radiotherapy for Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: RADIATION: radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Consumption of Date Fruit and Nipple Stimulation in Late Pregnancy
Status: COMPLETED
Conditions: Augmentation|Induction|Labor|Stimulation, Self
Interventions: OTHER: Date Fruit group|OTHER: Nipple group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ensartinib in Combination With Bevacizumab in ALK-positive NSCLC Patients With TP53 Mutation
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Ensartinib|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 16 Week Study Evaluating Levetiracetam in the Treatment of Post Herpetic Neuralgia (PHN)
Status: COMPLETED
Conditions: Neuralgia, Postherpetic
Interventions: DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Neoadjuvant Pembrolizumab Plus Chemotherapy for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Pembrolizumab|DRUG: Carboplatin or Cisplatin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Catheter Ablation Versus Antiarrhythmic Drugs for Outflow Tract Ventricular ARrhythmias
Status: UNKNOWN
Conditions: Ventricular Tachycardia|Ventricular Premature Complexes
Interventions: DRUG: antiarrhythmic drugs (Flecainide or Propafenone or Sotalol)|PROCEDURE: Catheter Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Application of MT in Subjects With Overweight/Metabolic Abnormality---RCT
Status: COMPLETED
Conditions: Overweight|Metabolic Abnormality
Interventions: DEVICE: Mobile physical activity promotion tool|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial of SHR-1210 (an Anti-PD-1 Inhibitor) in Combination With Hypofraction Radiotherapy in Patients With NSCLC
Status: UNKNOWN
Conditions: Non-Small-Cell Lung Cancer
Interventions: DRUG: SHR-1210
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Switching From Epzicom to Truvada
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: emtricitabine (FTC)/tenofovir disoproxil fumarate (TDF)|DRUG: abacavir (ABC)/lamivudine (3TC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics and Safety of K-808 (Pemafibrate) in Subjects With Primary Biliary Cholangitis With Compensated Cirrhosis and Without Cirrhosis.
Status: NOT_YET_RECRUITING
Conditions: Primary Biliary Cholangitis|Compensated Cirrhosis
Interventions: DRUG: K-808
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MR-Guided High-Intensity Focused Ultrasound in Conjunction With Radiation Therapy for the Treatment of Locally Advanced Cervical Cancer
Status: WITHDRAWN
Conditions: Locally Advanced Cervical Cancer
Interventions: DEVICE: Sonalleve Magnetic Resonance-guided High Intensity Focused Ultrasound (MR-HIFU)|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Near-Infrared Spectroscopy and Virtual Reality Relaxation Programs for Pain Management in Patients With Cancer
Status: RECRUITING
Conditions: Breast Carcinoma|Kidney Carcinoma|Malignant Solid Neoplasm|Malignant Thoracic Neoplasm
Interventions: PROCEDURE: Functional Near-Infrared Spectroscopy|OTHER: Questionnaire Administration|OTHER: Virtual Technology Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Four Quadrants Transverse Abdominus Plane (4Q-TAP) Block With Plain and Liposomal Bupivacaine vs. Thoracic Epidermal Analgesia (TEA) in Patients Undergoing Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) on an Enhanced Recovery Pathway
Status: COMPLETED
Conditions: Peritoneal Cancer
Interventions: DRUG: Local Anesthetic Solution|DRUG: Bupivacaine HCl|DRUG: Liposomal Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Food for Special Dietary Use - Spread Enriched With 5-hydroxytryptophan, Theanine and Gamma-aminobutyric Acid on Psychophysiological Functions of Subjects Without Meaningful Organic and Cognitive Pathology
Status: COMPLETED
Conditions: Cognitive Change|Memory; Disturbance, Mild|Emotional Regulation|Concentration Ability Impaired
Interventions: DIETARY_SUPPLEMENT: Food for special dietary use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 3D Ultrasound-guided Labor Epidural Analgesia in the Morbid Obese Parturient
Status: TERMINATED
Conditions: Obesity, Morbid|Pregnancy|Pain
Interventions: DEVICE: Rivanna Accuro 3D Ultrasound Device|OTHER: Palpation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of VX-809 Alone and in Combination With VX-770 in Cystic Fibrosis (CF) Patients Homozygous or Heterozygous for the F508del-CFTR Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Lumacaftor|DRUG: Ivacaftor|DRUG: Lumacaftor Placebo|DRUG: Ivacaftor Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DNA Sequencing-Based Monitoring of Minimal Residual Disease to Predict Clinical Relapse in Aggressive B-cell Non-Hodgkin Lymphomas
Status: ACTIVE_NOT_RECRUITING
Conditions: B-cell Non-Hodgkin Lymphoma|Aggressive
Interventions: OTHER: collected at pre-treatment tumor biopsy|OTHER: Peripheral blood tests|DEVICE: PET/CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CRF1 Antagonist GSK561679 in Alcoholism
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: GSK561679|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With HIV-Associated Non-Hodgkin or Hodgkin Lymphoma
Status: WITHDRAWN
Conditions: Adult Nasal Type Extranodal NK/T-cell Lymphoma|AIDS-related Diffuse Large Cell Lymphoma|AIDS-related Diffuse Mixed Cell Lymphoma|AIDS-related Diffuse Small Cleaved Cell Lymphoma|AIDS-related Immunoblastic Large Cell Lymphoma|AIDS-related Lymphoblastic Lymphoma|AIDS-related Peripheral/Systemic Lymphoma|AIDS-related Small Noncleaved Cell Lymphoma|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Cutaneous B-cell Non-Hodgkin Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Hepatosplenic T-cell Lymphoma|HIV-associated Hodgkin Lymphoma|Intraocular Lymphoma|Nodal Marginal Zone B-cell Lymphoma|Noncutaneous Extranodal Lymphoma|Peripheral T-cell Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Refractory Hairy Cell Leukemia|Small Intestine Lymphoma|Splenic Marginal Zone Lymphoma|Stage I AIDS-related Lymphoma|Stage II AIDS-related Lymphoma|Stage III AIDS-related Lymphoma|Stage IV AIDS-related Lymphoma|T-cell Large Granular Lymphocyte Leukemia|Testicular Lymphoma|Waldenström Macroglobulinemia
Interventions: DRUG: carmustine|DRUG: cytarabine|DRUG: melphalan|DRUG: etoposide|DRUG: O6-benzylguanine|PROCEDURE: autologous hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 12 Week Study of Anti-Viral Effect of Oral UT-231B in Non-cirrhotic Hepatitis C Patients who have Failed Interferon-based Therapy.
Status: UNKNOWN
Conditions: Hepatitis C
Interventions: DRUG: UT-231B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and Carboplatin With Or Without Sorafenib In The First-Line Treatment Of Patients With Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Sorafenib|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Colon Delivered Vitamin B2 on Gut Microbiota and Related Health Biomarkers in Healthy Older Adults
Status: RECRUITING
Conditions: Quality of Life
Interventions: DIETARY_SUPPLEMENT: Riboflavin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pyrotinib Maleate, CDK4/6 Inhibitor and Letrozole in Combination for Stage II-III TPBC: a Phase II Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Pyrotinib maleate, SHR6390, letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Assessment of the Aria CV System in Patients With WHO Groups 2 and 3 Pulmonary Hypertension
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DEVICE: Aria CV Acute PH System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TREND-HD - A Trial of Ethyl-EPA (Miraxion™) in Treating Mild to Moderate Huntington's Disease
Status: COMPLETED
Conditions: Huntington Disease
Interventions: DRUG: Ethyl-EPA (Miraxion™)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study to Investigate the Impact of Diamyd in Patients Newly Diagnosed With Type 1 Diabetes (EU)
Status: TERMINATED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: rhGAD65|DRUG: rhGAD65|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of AZD8233 in Participants With Dyslipidemia.
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: Part A:Placebo|DRUG: Part A:AZD8233|DRUG: Part B:Placebo|DRUG: Part B:AZD8233|DRUG: Part C: Placebo|DRUG: Part C: AZD8233
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Cranial Electrotherapy Stimulation on Anxiety of Patients After COVID-19
Status: COMPLETED
Conditions: POST-Covid 19|Anxiety
Interventions: DEVICE: Application of CES via ear clips|DEVICE: Sham: No application of CES via ear clips
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Mindfulness Based Relapse Prevention for Chronic Users of Benzodiazepines
Status: COMPLETED
Conditions: Benzodiazepine Dependence
Interventions: BEHAVIORAL: Mindfulness-Based Relapse Prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE