pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Respiratory Sinus Arrhythmia Pacing Post-CABG Surgery in Patients With HFrEF
Status: NOT_YET_RECRUITING
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: DEVICE: Atrial pacing with respiratory sinus arrhythmia (RSA) variability|DEVICE: Monotonic right atrial overdrive pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of FSME-IMMUN NEW in Healthy Children and Adolescents Aged 1 to 15 Years
Status: COMPLETED
Conditions: Tick-borne Encephalitis
Interventions: BIOLOGICAL: FSME-IMMUN NEW 0.25 ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study Comparing ETS6103 With Amitriptyline in the Treatment of Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: ETS6103 (low dose)|DRUG: ETS6103 (high dose)|DRUG: Amitriptyline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prucalopride for Postoperative Ileus in Patients Undergoing Robot-assisted Laparoscopic Radical Cystectomy
Status: UNKNOWN
Conditions: Postoperative Ileus|Bladder Cancer
Interventions: DRUG: Prucalopride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mobilization for Post Partum Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain, Mechanical
Interventions: PROCEDURE: mobilization (manual therapy)|PROCEDURE: Placebo mobilization|DEVICE: Ultrasound and infrared devices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of RBT-9 on Progression of COVID-19 in High-Risk Individuals (The PREVENT Study)
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: RBT-9 (90 mg)|DRUG: 0.9% sodium chloride (normal saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Discharge ALERT: Quality Improvement Initiative
Status: COMPLETED
Conditions: Pulmonary Embolism|Deep Vein Thrombosis|Prophylaxis|Venous Thromboembolism|Prevention
Interventions: BEHAVIORAL: Alert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Using Sitagliptin as a Treatment to Prevent New Onset Diabetes After Kidney Transplantation
Status: TERMINATED
Conditions: Type 2 Diabetes|End Stage Renal Disease
Interventions: DRUG: Placebo|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Simulated Standard Versus Modified Jaw Thrust I-gel Insertion Technique in Novice Anesthesiologists
Status: COMPLETED
Conditions: Training Group, Sensitivity|Igel
Interventions: DEVICE: I-gel with standard insertion technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prasugrel Versus Ticagrelor in Patients With CYP2C19 Loss-of-function: a Validation Study
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Prasugrel|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Donepezil Hydrochloride (Aricept) in Vascular Dementia
Status: COMPLETED
Conditions: Vascular Dementia
Interventions: DRUG: donepezil hydrochloride (Aricept)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: F-CaST for Individuals With Substance Use Disorder
Status: COMPLETED
Conditions: Substance Use Disorders
Interventions: OTHER: Functional Cognitive and Sensory Treatment (F-CaST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Assess the Efficacy and Safety of Eutropin in Prader-Willi Syndrome
Status: COMPLETED
Conditions: Prader-Willi Syndrome
Interventions: DRUG: Eutropin|DRUG: Genotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of Machine Learning Models for the Prediction of Complications After Colonic, Colorectal and Small Intestine Anastomosis in Psychiatric and Non-psychiatric Patient Collectives (P-Study)
Status: RECRUITING
Conditions: Postoperative Complications|Psychosomatic Disorder|Psychiatric Disorder|Cancer|Diverticulitis|Morbus Crohn|Colitis Ulcerosa|Anastomotic Leak|Anastomotic Complication|Small Intestine Anastomotic Leak
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ketamine in the Treatment of Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Ketamine|DRUG: Saline|PROCEDURE: Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ursodiol for Treating Parenteral Nutrition Associated Cholestasis in Neonates
Status: COMPLETED
Conditions: Cholestasis
Interventions: DRUG: Ursodiol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing a Horizontal Ultrasound Technique With a Palpation Technique for Localising the Cricothyroid Membrane
Status: COMPLETED
Conditions: Airway Identification
Interventions: OTHER: ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Automated Prize-based Contingency Management to Increase Counseling Attendance in Opiate-Replacement-Therapy Patients
Status: COMPLETED
Conditions: Opiate-Replacement Therapy
Interventions: DEVICE: Automated Contingency Management (ACM) software
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Omega-3 Fatty Acid Therapy in Preventing Gastrointestinal Bleeding in Patients With CF-LVAD
Status: TERMINATED
Conditions: Heart Failure|Gastrointestinal Bleeding
Interventions: DRUG: Omega 3 fatty acids|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cisplatin, Interferon Alfa, Surgery, and Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Malignant Mesothelioma
Interventions: BIOLOGICAL: recombinant interferon alfa|DRUG: cisplatin|PROCEDURE: surgical procedure|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ⅱ Clinical Study of Sanhuangjingshimingwan in Wet( Neovascular)Age-related Macular Degeneration(wAMD) Subjects
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: DRUG: Sanhuangjingshimingwan|DRUG: Sanhuangjingshimingwan Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stopping Antibiotics After 3 Days for the Treatment of High-risk FEbrile Neutropenia
Status: RECRUITING
Conditions: Neutropenia, Febrile
Interventions: OTHER: Comparison short vs extended EBAT treatment group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical and Immunological Efficiency of Bacterial Vaccines at Adult Patients With Bronchopulmonary Pathology
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Asthma|Pneumococcal Infections
Interventions: BIOLOGICAL: Prevenar-13|BIOLOGICAL: Pneumo-23
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Two Oral Formulations of LX4211 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: 300 mg LX4211 (150 mg tablets)|DRUG: 300 mg LX4211 (50 mg tablets)|DRUG: 300 mg LX4211 (liquid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study Evaluating the Performance of Nanotite Osseotite Implants When Placed by Graduate Student Programs
Status: COMPLETED
Conditions: Tooth Disease|Partial Edentulism
Interventions: DEVICE: Nanotite dental implant|DEVICE: Osseotite dental implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole-body Vibration on Mucus Clearance, the Quality of Life, and Exercise Capacity for Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: COPD
Interventions: DEVICE: A vertical vibration platform PowerVibe Zen Pro 5900|DEVICE: HFCWO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Shared Listening to Personalized Music on Symptoms of Behavioral Disorders in the Elderly With Advanced Dementia
Status: UNKNOWN
Conditions: Dementia
Interventions: COMBINATION_PRODUCT: 2gether app used by trained personal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mycophenolate Mofetil 250 mg Capsules Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Mycophenolate Mofetil|DRUG: CellCept®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of AxoGuard® Nerve Cap and Neurectomy for Treatment of Symptomatic Neuroma & Prevention of Recurrent Neuroma Pain
Status: COMPLETED
Conditions: Symptomatic Neuroma|Morton's Neuroma|Chronic Nerve Pain
Interventions: DEVICE: AxoGuard® Nerve Cap|PROCEDURE: Standard Neurectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Tissue Oxygen Saturation and Blood Transfusion in Cardiac Surgery
Status: COMPLETED
Conditions: Blood Transfusion|Cardiac Surgery
Interventions: PROCEDURE: Brain tissue oxygen saturation monitoring|PROCEDURE: Transfusion according to the anesthesiologist's judgement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of a Theory Based Educational Intervention on Medication Adherence to and Removes of Related Barriers in Patients With Bipolar Disorder
Status: COMPLETED
Conditions: Patients With Bipolar Disorders
Interventions: BEHAVIORAL: Multifaceted intervention|BEHAVIORAL: Routine counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sukalmena InAge: Nutritional-culinary Programme to Promote Adherence to a Healthy Dietary Pattern.
Status: COMPLETED
Conditions: Obesity|Healthy Aging|Cognitive Impairment
Interventions: BEHAVIORAL: Mediterranean diet-based nutritional education intervention|BEHAVIORAL: Mediterranean diet-based culinary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Epidural Steroid Use in Patients With Continous Epidural Block in PHN Patients.
Status: UNKNOWN
Conditions: Neuralgia,Postherpetic
Interventions: DRUG: Dexamethasone|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Histrelin Subdermal Implant in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Adenocarcinoma of the Prostate
Interventions: DRUG: Histrelin hydrogel implant|DRUG: Zoladex goserelin implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flavonoid Effect on Activation and Stimulation of Thrombocytes, hsCRP and Lipid Profile
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Green tea|DIETARY_SUPPLEMENT: 70% dark chocolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BNT162b2 Messenger Ribonucleic Acid (mRNA) Covid-19 Vaccine in Cancer Patients on Active Treatment
Status: UNKNOWN
Conditions: Neoplasms|Cancer, Treatment-Related
Interventions: BIOLOGICAL: BNT162b2 mRNA Covid-19 Vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CSDM: A Trial to Improve Communication and Shared Decision Making Using a Web-Based Tool
Status: COMPLETED
Conditions: Intervention Compliance|Usability|Acceptability
Interventions: OTHER: CSDM Web-Based Tool Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Tolerability of Inhaled Hypertonic Saline in Infants With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: inhaled 7% hypertonic saline (HS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development, Validation and Evaluation of an Adult and Pediatric Eosinophilic Esophagitis Activity Index
Status: UNKNOWN
Conditions: Deglutition Disorders|Esophageal Diseases|Eosinophilia
Interventions: OTHER: assessment of disease activity using the EEsAI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analgesic and Subjective Effects of Terpenes
Status: RECRUITING
Conditions: Pain|Abuse, Drug
Interventions: DRUG: Low THC|DRUG: High THC|DRUG: Low Myrcene|DRUG: High Myrcene|DRUG: Low Beta-Caryophyllene|DRUG: High Beta-Caryophyllene|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Deep Brain Stimulation (DBS) of the Pedunculopontine Nucleus (PPN)
Status: ENROLLING_BY_INVITATION
Conditions: Parkinson Disease
Interventions: DEVICE: STN-PPN DBS Surgery|PROCEDURE: Deep Brain Stimulation Surgery (DBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TARGET Post-Approval Study
Status: COMPLETED
Conditions: Complex Regional Pain Syndrome (CRPS)
Interventions: DEVICE: Dorsal Root Ganglion (DRG) Stimulation (Axium™ Neurostimulator System)|DEVICE: Dorsal Root Ganglion (DRG) Stimulation (Proclaim™ Neurostimulator System)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Doxorubicin Plus Dual Checkpoint Blockade for Soft Tissue Sarcomas
Status: RECRUITING
Conditions: Metastatic Soft Tissue Sarcoma|Advanced Soft Tissue Sarcoma
Interventions: DRUG: Balstilimab|DRUG: Zalifrelimab|DRUG: Doxorubicin|DRUG: Botensilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Smartphone-based Screening Tool (Picterus Jaundice Pro) for Neonatal Jaundice in Dark Skin Newborns
Status: COMPLETED
Conditions: Jaundice, Neonatal
Interventions: DEVICE: Picterus Jaundice Pro
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: An Exploratory Study of 18F-Labeled Hydroxyphenethylguanidines in Heart Failure Patients
Status: COMPLETED
Conditions: Cardiomyopathy
Interventions: DRUG: [18F]4F-MHPG|DRUG: [18F]3F-PHPG|DRUG: [13N]ammonia|DRUG: [11C]HED
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CAM in Post Surgical Management in Cardiothoracic Surgery
Status: UNKNOWN
Conditions: Patients Undergoing Open Heart Surgery|Patients Undergoing Lung Surgery
Interventions: OTHER: Acupuncture, homeopathy, osteopathy- and reflexology|DRUG: Homeopathic placebo medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Pharmacokinetics Study of IDP-122 Lotion in Pediatric Participants With Plaque Psoriasis
Status: RECRUITING
Conditions: Psoriasis
Interventions: DRUG: IDP-122 Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy and Safety of ADL5859 in Subjects With Acute Dental Pain After Third Molar Extraction
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Placebo|DRUG: ADL5859 30 mg|DRUG: ADL5859 100 mg|DRUG: ADL5859 200 mg|DRUG: ibuprofen 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study on the Efficacy and Safety of Xuanfei Baidu Granule in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Status: RECRUITING
Conditions: Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Xuanfei Baidu granule|DRUG: Xuanfei Baidu granule Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BackToBasic: Infliximab in Chronic Low Back Pain and Modic Changes
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Biosimilar Infliximab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Photobiomodulation on Superficial Sensitivity and Muscle Activity of Individuals With Myelomeningocele
Status: UNKNOWN
Conditions: Myelomeningocele Without Hydrocephalus|Sensory Defect|Motor Activity
Interventions: DEVICE: Low level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Melatonin and Metformin Loaded Nanoparticles in the Treatment of Periodontal Intra-bony Defects
Status: ENROLLING_BY_INVITATION
Conditions: Bone Loss in Jaw
Interventions: DRUG: Melatonin gel|DRUG: Metformin and melatonin gel|DRUG: placebo gel|PROCEDURE: scaling and root planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HOLT-ED: Holter-monitoring in End-stage Renal Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Failure, Chronic|Arrhythmias, Cardiac|Heart Diseases|Cardiovascular Diseases|Kidney Diseases|Renal Insufficiency, Chronic|Renal Insufficiency
Interventions: DEVICE: Holter-monitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetic Interaction Between Trospium With an Inhibitor of OCT1 and of P-gp in Subjects Genotyped for OCT1
Status: COMPLETED
Conditions: Pharmacokinetics|Inhibition Enzyme|Drug Interaction Potentiation
Interventions: DRUG: intravenous infusion of 2 mg trospium chloride|DRUG: oral administration of 30 mg trospium chloride|DRUG: oral administration of 300 mg ranitidine|DRUG: oral administration of 500 mg clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of a Fibrin Sealant for the Prevention of Lymphocele After Lymphadenectomy
Status: COMPLETED
Conditions: Lymphocele
Interventions: BIOLOGICAL: Fibrin sealant hemipelvis|BIOLOGICAL: Control hemipelvis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Gingest on Symptoms of Dyspepsia
Status: COMPLETED
Conditions: Dyspepsia|Epigastric Fullness|Bloating|Epigastric Pain
Interventions: DIETARY_SUPPLEMENT: Gingest powdered extract obtained from Ginger rhizomes|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of an Immediate Preoperative Chemotherapy Before Resection fo Colorectal Cancer
Status: TERMINATED
Conditions: Patients With Colorectal Cancer With Unresectable Synchronous Metastasis in Whom Resection of the Primitive Tumour is Indicated
Interventions: DRUG: Oxaliplatin|DRUG: Folinic Acid|DRUG: Fluorouracile
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Safety and Efficacy of RP-L201 in Subjects With Leukocyte Adhesion Deficiency-I
Status: COMPLETED
Conditions: Leukocyte Adhesion Defect - Type I
Interventions: BIOLOGICAL: RP-L201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: G-CSF and Pegfilgrastim in Treating Neutropenia in Patients Undergoing Radiation Therapy and Chemotherapy for Limited Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Filgrastim|DRUG: Pegfilgrastim|DRUG: Etoposide|DRUG: Cisplatin|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity Safety Study of Wockhardt's Recombinant Insulin Analogue in Type 1 Diabetic Patients
Status: WITHDRAWN
Conditions: Type I Diabetes
Interventions: BIOLOGICAL: Wockhardt's Insulin Analogue (Recomb)|BIOLOGICAL: Lantus®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenetic Trial of Tacrolimus After Pediatric Transplantation
Status: COMPLETED
Conditions: Heart Transplantation|Liver Transplantation|Kidney Transplantation
Interventions: DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Snack Foods and Their Impact on the Immune Response Following Influenza Vaccination
Status: RECRUITING
Conditions: Immune Response
Interventions: DIETARY_SUPPLEMENT: Intervention snack|DIETARY_SUPPLEMENT: Control snack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment for Malignant Ovarian Cancer: Laparoscopy vs Laparotomy
Status: UNKNOWN
Conditions: Ovarian Cancer
Interventions: PROCEDURE: Laparoscopy|PROCEDURE: Laparotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acoustic Cough Monitoring for the Management of Patients With Known Respiratory Disease
Status: RECRUITING
Conditions: Cough|COPD|GERD|Asthma|Tuberculosis|Non-Tuberculous Mycobacterial Pneumonia|COVID-19 Pneumonia
Interventions: DEVICE: Hyfe Cough Tracker|DEVICE: Hyfe Air
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adoptive TKC Transfer Combined With Chemotherapy for Advanced Non-small Cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: Advanced Non-small Cell Lung Cancer|Chemotherapy
Interventions: DRUG: Chemotherapy|BIOLOGICAL: Adoptive TKC transfer therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sintilimab in Combination With S-1/Oxaliplatin With Nab-paclitaxel Intraperitoneal Infusion for Untreated Advanced Gastric Cancer With Malignant Ascites
Status: RECRUITING
Conditions: Gastric Cancer|Peritoneal Metastases|Ascites, Malignant
Interventions: DRUG: Sintilimab in Combination With S-1/oxaliplatin With nab-paclitaxel intraperitoneal infusion|OTHER: Blood samples, tumor biopsy specimens, ascites, and feces samples will be collected
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prognostic Value of Combined Approach Based on KEAP1/NFE2L2 Mutations and Pre-therapeutic FDG-PET/CT Radiomic Analysis in Advanced Non-small-cell Lung Cancer PDL1 ≥ 50% Treated With Pembrolizumab (PEMBROMIC)
Status: RECRUITING
Conditions: Lung Cancer Stage III|Lung Cancer Stage IV
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: RP72 Monotherapy and in Combination With Gemcitabine in Patients With Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer|Pancreatic Cancer Non-resectable|Pancreatic Cancer Metastatic
Interventions: DRUG: RP72|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Nordic DeltaCon Trial for Displaced Proximal Humeral Fractures in Elderly
Status: ACTIVE_NOT_RECRUITING
Conditions: Proximal Humeral Fracture
Interventions: PROCEDURE: Operative treatment with Reversed Total Shoulder Prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mifepristone Versus Misoprostol for Cervical Preparation Prior to Surgical Abortion Between 11 to 15 Weeks
Status: TERMINATED
Conditions: Induced Abortion|Abortion Techniques|Mifepristone|Misoprostol
Interventions: DRUG: Mifepristone|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-contrast Enhanced Cardiac Magnetic Resonance Imaging in the Diagnosis and Classification of Pulmonary Hypertension
Status: ENROLLING_BY_INVITATION
Conditions: Pulmonary Hypertension|Elevated Mean Pulmonary Arterial Pressure|Normal Mean Pulmonary Arterial Pressure
Interventions: OTHER: Cardiac MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Rituximab and Dexamethasone in Treating Patients With Recurrent or Refractory Indolent Non-Hodgkin's Lymphoma
Status: WITHDRAWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Use of Short Text Messages to Promote Medication Adherence in Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension|Adherence, Treatment
Interventions: OTHER: Educational short message texts|OTHER: Adherence short message texts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Chronic Pain Diagnosis and Treatment in Torture Survivors
Status: RECRUITING
Conditions: Pain|Pain, Chronic
Interventions: OTHER: Pain Evaluation and BPISF|OTHER: Surveys, a fingerstick blood sample, EMAs, and a digital wearable device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: COMMETS- Combination MCI Metabolic Syndrome
Status: RECRUITING
Conditions: Alzheimer Disease|Mild Cognitive Impairment|Metabolic Syndrome
Interventions: DRUG: Semaglutide|DRUG: Intranasal insulin|OTHER: Semaglutide placebo|OTHER: Intranasal insulin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lung Collapse With Bronchial Blocker
Status: COMPLETED
Conditions: Video-assisted Thoracoscopic Surgery|Lung Isolation Device|One-lung Ventilation|Double Lumen Endotracheal Tube|Bronchial Blocker
Interventions: DEVICE: Lung isolation device|DEVICE: Lung isolation device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose:
Clinical trial: Efficacy and Safety of Deferasirox in Patients With Chronic Anemia and Transfusional Hemosiderosis
Status: COMPLETED
Conditions: Chronic Anemia|Transfusional Hemosiderosis
Interventions: DRUG: Deferasirox (ICL670)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Extension Study of Pramipexole in the Treatment of Children and Adolescents With Tourette Syndrome
Status: TERMINATED
Conditions: Tourette Syndrome
Interventions: DRUG: pramipexole 0.125 mg BID|DRUG: pramipexole 0.0625 mg QD|DRUG: pramipexole 0.125 mg TID|DRUG: pramipexole 0.25 mg BID|DRUG: pramipexole 0.0625 mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence Study of Gastrointestinal Risk Factors in Patients With Osteoarthritis (OA), Rheumatoid Arthritis (RA) and Ankylosing Spondylitis (AS).
Status: COMPLETED
Conditions: Osteoarthritis (OA)|Rheumatoid Arthritis (RA)|Ankylosing Spondylitis (AS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TachoComb S Versus Standard Surgical Treatment in Surgical Resection of Renal Tumour (TC-015-IN)
Status: COMPLETED
Conditions: Surgical Resection of Superficial Renal Tumour
Interventions: PROCEDURE: Fibrinogen (human) + thrombin (human) (TachoSil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ulipristal Acetate Versus GnRH Analogue and Myometrial Preservation
Status: UNKNOWN
Conditions: Fibroid
Interventions: DRUG: ulipristal acetate|DRUG: Leuprolide acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carboplatin, Temozolomide, and Filgrastim in Treating Patients With Newly Diagnosed or Recurrent High-Grade Glioma
Status: WITHDRAWN
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Anabolic Steroids for Nutritional Rehabilitation of Critically Ill Patients
Status: TERMINATED
Conditions: Malnutrition|Critical Illness
Interventions: DRUG: Nandrolone (anabolic steroid)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Diabetes Equity and Advancing Care Study
Status: RECRUITING
Conditions: Diabetes|Diabetes Mellitus|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Diabetes Self-Management Training (DSMT)|BEHAVIORAL: Remote Glucose Monitoring (RGM)|BEHAVIORAL: Community Health Worker tailored support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fundal Block in Pre-menopausal Women to Reduce Pain During Outpatient-based Endometrial Ablation (FUNDAL-PAIN)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain
Interventions: DRUG: Xylocaine 1 % and Normal Saline|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Internet-delivered Treatment for Transgender Individuals With Co-occurring Mental Health Problems
Status: COMPLETED
Conditions: Gender Dysphoria|Emotion Regulation|Internet Delivered Treatment
Interventions: BEHAVIORAL: IERGD|OTHER: IER SUPPORT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbiome Development in the Early Healing of Osseointegrated Implants
Status: COMPLETED
Conditions: Microbiota|Dental Implants
Interventions: OTHER: Dental implant surface
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Therapeutic Effect of Different Exercise Intensities on Weight Loss in Obese Children
Status: NOT_YET_RECRUITING
Conditions: Weight Loss|Obese Children and Adolescents
Interventions: BEHAVIORAL: high-intensity interval training|BEHAVIORAL: moderate intensity continuous training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Applying Best Clinical Practices to Patients at High Risk of Respiratory Complications
Status: ACTIVE_NOT_RECRUITING
Conditions: Respiratory Complication|Obstructive Sleep Apnea
Interventions: DRUG: Sugammadex 100 MG/ML [Bridion]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Efficacy and Safety Study of Dapirolizumab Pegol (DZP) in Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus (SLE)
Interventions: DRUG: Placebo|DRUG: Dapirolizumab pegol (DZP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of PR Oxycodone/Naloxone and PR Oxycodone After Cardiac Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Opioid Related Disorders
Interventions: DRUG: Oxycodone|DRUG: Prolonged-release oxycodone/naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Versus Midazolam-Fentanyl for Analgesia and Sedation
Status: RECRUITING
Conditions: Valvular Cardiac Surgeries
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Goal Directed Sedation on Microcirculation in Septic Shock
Status: UNKNOWN
Conditions: Septic Shock
Interventions: DRUG: Dexmedetomidine for sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Copanlisib Plus Venetoclax in R/R DLBCL
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B Cell Lymphoma|Relapsed Diffuse Large B-Cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Copanlisib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Pharmacokinetics of Extended Duration High-dose Cefixime for the Decreased Susceptibility of Neisseria Gonorrhoeae: A Phase I Pilot Study
Status: COMPLETED
Conditions: Gonorrhoea
Interventions: DRUG: Cefixime
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Abdominal Muscle Activation Training, Using Pressure Biofeedback in Comparison With Surface Electromyography
Status: RECRUITING
Conditions: Low Back Pain
Interventions: PROCEDURE: Abdominal activation using pressure biofeedback|PROCEDURE: Abdominal activation using SEMG biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Weekly Dosing of SCH 727965 in Patients With Advanced Cancer (Study P04629AM6)
Status: COMPLETED
Conditions: Solid Tumors|Lymphoma, Non-Hodgkin|Multiple Myeloma|Leukemia, Lymphocytic, Chronic. B-Cell
Interventions: DRUG: SCH 727965
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Preemptive Analgesia With Flurbiprofen Axetil on Perioperative Sleep Quality and Postoperative Pain in Patients Undergoing Sevoflurane Inhalation.
Status: UNKNOWN
Conditions: Flurbiprofen Axetil|Preemptive Analgesia|Postoperative Pain|Perioperative Sleep Quality|Postoperative Inflammatory Markers
Interventions: DRUG: Flurbiprofen axetil preoperatively|DRUG: Flurbiprofen axetil postoperatively
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy of Atherectomy Plus Drug-coated Balloon Versus Drug-coated Balloon for Complex Femoropopliteal Artery Disease
Status: RECRUITING
Conditions: Femoropopliteal Artery Disease
Interventions: PROCEDURE: Combination therapy of atherectomy and DCB|PROCEDURE: DCB alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Fecal Microbiota Transplantation for Constipation in Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DRUG: Healthy donor-derived FMT capsule|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rhomboid Intercostal and Subserratus Plane Block
Status: COMPLETED
Conditions: Postoperative Pain|Regional Anesthesia Morbidity
Interventions: PROCEDURE: Control group|PROCEDURE: Rhomboid intercostal and subserratus plane block group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Strict Volume Control in Hypertensive Hemodialysis Patients on Cardiac Structure and Chronic Inflammation
Status: COMPLETED
Conditions: End-stage Renal Disease
Interventions: PROCEDURE: strict volume control policy|PROCEDURE: antihypertensive drugs administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Empagliflozin on Macrovascular and Microvascular Circulation and on Endothelium Function
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Empagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HBsAg Loss/Seroconversion in Low Replicative Chronic Hepatitis B Virus(HBV) Infection Patients
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: peginterferon alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of a Late-Life Schizophrenia Integrated Care Pathway to Treat Acute Psychotic Symptoms
Status: UNKNOWN
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: OTHER: Late-life Schizophrenia ICP|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anal Dysplasia in Patients With Inflammatory Bowel Disease and Healthy Controls
Status: COMPLETED
Conditions: Anal Squamous Intraepithelial Lesion (ASIL)|HPV DNA
Interventions: PROCEDURE: Anal Pap smear and HPV DNA testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: The Clinical Significance of Portal Hypertension After Cardiac Surgery: a Multicenter Prospective Observational Study
Status: COMPLETED
Conditions: Surgery--Complications|Congestive Heart Failure|Right Heart Failure|Anesthesia|Venous Congestion
Interventions: DIAGNOSTIC_TEST: Doppler assessment of portal vein flow
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rheumatology-based Adaptive Intervention for Social Determinants and Health Equity
Status: RECRUITING
Conditions: Rheumatoid Arthritis|Palindromic Arthritis|Juvenile Rheumatoid Arthritis|Ankylosing Spondylitis|Sacroiliitis|Psoriatic Arthritis|Mixed Connective Tissue Disease|Lupus|Enteropathic Arthropathies|Systemic Sclerosis|Sjogren's Syndrome|Sicca Syndrome|Inflammatory Arthritis|Undifferentiated Connective Tissue Diseases
Interventions: OTHER: Resource sheets|OTHER: Community Resource Specialist|OTHER: Nurse Navigator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Implantation of Porous Titanium Prosthesis in Laryngeal Surgery
Status: UNKNOWN
Conditions: Vocal Cord Paralysis
Interventions: DEVICE: Vocal fold medialization (thyroplasty) prosthesis by insertion of a new implant allowing very easy and quick setting
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microsoft Kinect, Gait Function,Hemineglect, Vestibulo-ocular Training
Status: COMPLETED
Conditions: Hemiplegic Gait
Interventions: OTHER: vestibuloocular training|OTHER: regular exercise training for hemiplegic patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Cholecystectomy - Fundus First and Harmonic Ace Compared With Conventional Technique
Status: COMPLETED
Conditions: Cholecystectomy
Interventions: PROCEDURE: Laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study of JNJ-28431754 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: JNJ 28431754 300 mg/placebo|DRUG: JNJ 28431754 100 mg/placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Periodontal Care on Rhematoid Arthritis in Uganda
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Periodontal Diseases
Interventions: PROCEDURE: Scaling and polishing|OTHER: oral hygiene instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Ilioinguinal Neurectomy During Open Tension-Free Inguinal Hernia Repair
Status: COMPLETED
Conditions: Ilioinguinal Nerve Section|Pain Prevention|Hernioplasty
Interventions: PROCEDURE: ilioinguinal nerve section
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Biochemical Markers of Growth Response to Growth Hormone Treatment in Children With Idiopathic Short Stature
Status: COMPLETED
Conditions: Idiopathic Short Stature
Interventions: DRUG: Somatotropin growth hormone recombinant human
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Characterize The Pharmacokinetics Of Oxycodone In Healthy Volunteers
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Oxycodone|DRUG: Oxycodone|DRUG: Oxycodone|DRUG: Oxycodone|DRUG: Oxycodone|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Analysis of Gait Before and After Botulinum Toxin Treatment in Patients With Focal Dystonia
Status: COMPLETED
Conditions: Cervical Dystonia, Primary|Blepharospasm
Interventions: OTHER: Treadmill|DRUG: Botulinum Toxin injection|DIAGNOSTIC_TEST: Severity scale of the disease
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of the Program on the Health Perceptions and Responsibilities of Immigrant Men on Utiling Healthcare Services
Status: COMPLETED
Conditions: Health Care Utilization|Men
Interventions: BEHAVIORAL: Increasising Health Awareness Program for Immigrant Men
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Double-blind, Placebo-controlled Clinical Trial of Fluvoxamine for Symptomatic Individuals With COVID-19 Infection
Status: COMPLETED
Conditions: COVID 19|Coronavirus
Interventions: DRUG: Fluvoxamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT