pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: German-funded Laparoscopic Approach to Cervical Cancer
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer
Interventions: PROCEDURE: Laparoscopic or robot-assisted radical/simple hysterectomy|PROCEDURE: Abdominal radical/simple hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Bevacizumab in Combination With Alternating Xeliri and Xelox in Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Bevacizumab plus alternating Xelox/Xeliri
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EVALUATION OF THE MACULAR, PERIPAPILLARY NERVE FIBER LAYER AND CHOROID THICKNESS CHANGES IN THE GESTATIONAL DIABETES MELLITUS, HEALTHY PREGNANT AND WOMEN VOLUNTEERS.
Status: COMPLETED
Conditions: Retinal Evaluation in Patients With GDM.
Interventions: OTHER: Pregnant volunteers with GDM
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral vs Intravenous Diltiazem for Rapid Atrial Fibrillation/Flutter Trial
Status: COMPLETED
Conditions: Atrial Fibrillation and Flutter
Interventions: DRUG: Diltiazem Oral Product|DRUG: Diltiazem Injectable Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of DOXIL/CAELYX in Patients With Advanced or Refractory Solid Malignancies Including Patients With Ovarian Cancer
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: DOXIL/CAELYX reference product (Treatment A)|DRUG: DOXIL/CAELYX test product (Treatment B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Using Octreotide to Enhance Liver Recovery After Hepatectomy
Status: TERMINATED
Conditions: Major Liver Resection
Interventions: DRUG: Octreotide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose-escalation, Safety, Pharmacokinetics Study of AVE8062 Combined With Bevacizumab in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms, Malignant
Interventions: DRUG: Ombrabulin (AVE8062)|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxepin Solution for Alleviation of Stubborn Breakthrough Pain Induced by Swallowing in Patients Receiving Radiotherapy for Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Swallowing-induced Pain
Interventions: DRUG: doxepin solution|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cerebral Blood Flow in Neonates During Thoracoscopic Surgeries
Status: UNKNOWN
Conditions: Tracheo Esophageal Fistula|Congenital Diaphragmatic Hernia
Interventions: DEVICE: cerebral oximetry ( INVOS 5100 )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Adult Protective Services Client Outcomes: A Stepped-Care Social and Mental Health Engagement Program
Status: RECRUITING
Conditions: Depression in Old Age
Interventions: BEHAVIORAL: Stepped-care social and mental health engagement|BEHAVIORAL: APS Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability, and Antiviral Activity of 24 or 48 Weeks of GS-9190 in Combination With Peginterferon Alfa 2a and Ribavirin for the Treatment of Genotype-1 Chronic HCV Infection
Status: COMPLETED
Conditions: HCV Infection
Interventions: DRUG: placebo|DRUG: GS-9190|DRUG: Peginterferon Alfa 2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/IIa Study on Chitin Microparticles in Subjects Suffering From Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Chitin microparticles by nasal route
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Development of Maternal Voice Recognition in Preterm Neonates
Status: COMPLETED
Conditions: Infant, Premature
Interventions: DEVICE: electroencephalogram (HR-EEG)|DEVICE: Near Infra Red Spectroscopy (NIRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ruxolitinib Prior to Transplant in Patients With Myelofibrosis
Status: TERMINATED
Conditions: Primary Myelofibrosis|Post Polycythemia Vera Myelofibrosis|Post Essential Thrombocythemia Myelofibrosis
Interventions: DRUG: Ruxolitinib Pre- Hematopoietic cell transplantation (HCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LOD vs Gn in Anovulatory PCOs Resistant to First Line Agents
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome|Anovulation
Interventions: PROCEDURE: Laparoscopic ovarian drilling|DRUG: Recombinant FSH (rFSH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effects of ALKS 4230 (Nemvaleukin Alfa) on Subjects With Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: ALKS 4230|DRUG: ALKS 4230 + pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Hydrogen Inhalation on Bronchiectasis: A Randomized, Multi-center, Double-blind Study
Status: UNKNOWN
Conditions: Bronchiectasis|Acute Exacerbation of Bronchiectasis|Oxidative Stress
Interventions: DEVICE: medical ultrasonic hydrogen/oxygen nebulizer (MUNHO)|DEVICE: Medical molecular mesh oxygen generator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed (ALIMTA) and Gefitinib (IRESSA®) in Never-Smoker and Adenocarcinoma Patients With Non-Small Cell Lung Cancer Previously Treated With Platinum-Based Chemotherapy
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: iressa|DRUG: alimta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Diastolic Cardiomyopathy (Aim3)
Status: COMPLETED
Conditions: Cardiomyopathy|Renal Impairment
Interventions: DRUG: Tadalafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy Study of AB002 (E-WE Thrombin) in End Stage Renal Disease Patients on Chronic Hemodialysis
Status: COMPLETED
Conditions: End Stage Renal Disease|Thrombosis
Interventions: DRUG: AB002 Dose 1|DRUG: AB002 Dose 2|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Aggressive hydraTion in Patients With ST -Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention to prevenT Contrast-Induced Nephropathy
Status: UNKNOWN
Conditions: ST Elevation Myocardial Infarction
Interventions: DRUG: Receiving hydration with a 1 mL/kg bolus of intravenous isotonic saline (0.9% sodium chloride)|DRUG: 3 mL/kg.hour bolus of intravenous isotonic saline (0.9% sodium chloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vitamin D Supplementation and Respiratory Index of Severity in Children (RISC) in Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Vitamin D3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ilium Mobilization in Patellofemoral Pain Syndrome Treatment
Status: RECRUITING
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: posterior ilium mobilization|OTHER: strengthening and stretching exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Explorative RVA of the Motor Development of Children With DCD <2y
Status: COMPLETED
Conditions: Developmental Coordination Disorder|Autism Spectrum Disorder
Interventions: DIAGNOSTIC_TEST: Movement Assessment Battery for Children 2(M-ABC-2)|DIAGNOSTIC_TEST: Developmental Coordination Disorder - Questionnaire (DCD-Q)|DIAGNOSTIC_TEST: Social Responsiveness Scale 2 (SRS-2)|OTHER: Retrospective Video Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multiple Ascending Dose (MAD) Study of IMT-002 in HLA-DQ8-positive Type 1 Diabetes
Status: COMPLETED
Conditions: Type1 Diabetes
Interventions: DRUG: 350mg BID (700mg total daily) IMT-002, D-methyldopa, active formulation in capsule or Placebo, microcrystalline cellulose in capsule|DRUG: 700mg BID (1400mg total daily) IMT-002, D-methyldopa, active formulation in capsule or Placebo, microcrystalline cellulose in capsule|DRUG: 1050mg QD (1050mg total daily) IMT-002, D-methyldopa, active formulation in capsule or Placebo, microcrystalline cellulose in capsule|DRUG: 1050mg BID (2100mg total daily) IMT-002, D-methyldopa, active formulation in capsule or Placebo, microcrystalline cellulose in capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Use of 5mg Finasteride Versus 200mg Spironolactone and Topical 5% Minoxidil in Treating Postmenopausal Female Androgenetic Alopecia
Status: WITHDRAWN
Conditions: Female Androgenetic Alopecia
Interventions: DRUG: 5% Minoxidil|DRUG: 200mg Spironolactone|DRUG: 5mg Finasteride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Model Informed preciSion doSIng tO iNdividualise and Optimize Pharmacotherapeutic Treatment
Status: NOT_YET_RECRUITING
Conditions: Pharmacokinetics|Area Under Curve|Tacrolimus|Immunosuppressive Agents|Mycophenolic Acid
Interventions: OTHER: venipuncture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Efficacy of Lenvatinib Combined With Denosumab in the Treatment of Patients With Predominant Bone Metastatic Radioiodine Refractory Differentiated Thyroid Carcinomas
Status: UNKNOWN
Conditions: Thyroid Cancer Metastatic
Interventions: DRUG: Lenvatinib + Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phenotyping of Idiopathic Pelvic Pain With Real-time Uterine Imaging and Relugolix-Combination Therapy Treatment
Status: NOT_YET_RECRUITING
Conditions: Pelvic Pain
Interventions: DRUG: Relugolix (40 mg) /estradiol (1 mg)/norethisterone acetate (0.5 mg) oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vaccination Trial of a Recombinant MVA-BN-WEV Vaccine in Healthy Adult Subjects
Status: COMPLETED
Conditions: Equine Encephalitis
Interventions: BIOLOGICAL: MVA-BN-WEV Dose 1|BIOLOGICAL: MVA-BN-WEV Dose 2|BIOLOGICAL: MVA-BN-WEV Dose 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Population Pharmacokinetic Modeling to Optimize the Dosage of the Piperacillin / Tazobactam Combination in Patients With Sepsis in Intensive Care
Status: RECRUITING
Conditions: Resuscitation Patients With Sepsis
Interventions: DRUG: pipéracilline/tazobactam
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Independent and Additive Effects Of Micronutrients With Metformin In Patients With PCOS
Status: COMPLETED
Conditions: PCOS
Interventions: DIETARY_SUPPLEMENT: Resveratrol|DRUG: Metformin|COMBINATION_PRODUCT: Acetyl-L-Carnitin, L Arginine, Co-Q10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nicotine Pharmacokinetics and Subjective Effects of Nicotine Pouch 1.0 Compared to Velo® Ice Cool and Zyn® Cool Mint Mini Dry in Healthy Smokers
Status: COMPLETED
Conditions: Smoking|Nicotine
Interventions: OTHER: NP-1|OTHER: NP-2|OTHER: NP-3|OTHER: NP-4|OTHER: Velo-NP|OTHER: Zyn-NP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Schroth Method on Pain, Body Awareness and Quality of Life in Adolescent Individuals With Idiopathic Scoliosis
Status: COMPLETED
Conditions: Scoliosis
Interventions: OTHER: exercise programme 1|OTHER: exercise programme 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Early Return-home After Colorectal Surgery Using a SENSIUM® Vital Parameter Monitoring Device
Status: RECRUITING
Conditions: Premature Exit After Colorectal Surgery
Interventions: DEVICE: SENSIUM Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase 2, Open-label, Single-arm Study on the Use of Metformin as Adjunctive Therapy in High-grade Glioma
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma, IDH-wildtype|Metformin|Malignancies
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Natural History, Pathogenesis, and Outcome of Autoinflammatory Diseases (NOMID/CAPS, DIRA, CANDLE, SAVI, NLRC4-MAS, Still'S-like Diseases, and Other Undifferentiated Autoinflammatory Diseases)
Status: RECRUITING
Conditions: NOMID|DIRA|NLRC4-MAS|SAVI|CANDLE
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Fate Of Calf Perforators After Endovenous Laser Ablation Of Saphenous Veins
Status: COMPLETED
Conditions: Venous Insufficiency
Interventions: PROCEDURE: Endovenous laser ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: South-seq: Deoxyribonucleic Acid (DNA) Sequencing for Newborn Nurseries in the South
Status: RECRUITING
Conditions: Whole Genome Sequencing
Interventions: BEHAVIORAL: Genetic Counselor|BEHAVIORAL: Trained Healthcare Provider
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Miltefosine for Brazilian Visceral Leishmaniasis
Status: TERMINATED
Conditions: Kala Azar
Interventions: DRUG: Miltefosine: initially 2.5 mg/kg/day for 28 days
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravaginal Electrical Nerve Stimulation in Women With Non-contracting Pelvic Floor
Status: COMPLETED
Conditions: Pelvic Floor|Muscle|Contraction|Electric Stimulation Therapy
Interventions: DEVICE: Intravaginal Electrical Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fludarabine or Chlorambucil as First-Line Therapy in Treating Older Patients With Previously Untreated Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Fludarabine|DRUG: Chlorambucil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetic Retina Exam Rate Does Not Increase With Phone Reminders in Non-HMO Population
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: BEHAVIORAL: phone call contact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: LOng-Term Fate of Moderate Aortic Regurgitation Left Untreated at the Time of Mitral Valve Surgery
Status: COMPLETED
Conditions: Aortic Regurgitation|Mitral Regurgitation
Interventions: PROCEDURE: Mitral valve surgery|PROCEDURE: Aortic valve surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Probiotics Lactobacillus in the Management of Attention Deficit Hyperactive Disorder
Status: COMPLETED
Conditions: Inattentive|Hyperactivity|Impulsivity
Interventions: DRUG: Probiotic Formula lacteal forte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Motivation To Quit Smoking In Smokers With Serious Mental Illness
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Long-Term Safety and Efficacy of Lanadelumab for Prevention of Acute Attacks of Non-histaminergic Angioedema With Normal C1-Inhibitor
Status: COMPLETED
Conditions: Angioedema
Interventions: DRUG: Lanadelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Retrograde Cholangiopancreatography (ERCP) With Cholangiopancreatoscopy Using a Thin Scope
Status: WITHDRAWN
Conditions: Disorders of the Pancreatobiliary System
Interventions: PROCEDURE: Endoscopic Retrograde Cholangiopancreatography (ERCP)with Cholangiopancreatoscopy using the thin scope
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effectiveness Pulmonary Telerehabilitation and Cognitive Telerehabilitation in COPD Patients
Status: COMPLETED
Conditions: Severe Chronic Obstructive Pulmonary Disease|Dyspnea|Muscle Weakness|Fatigue|Quality of Life|Muscle Strength|Motor Imagery|Functional Capacity|Muscle; Accessory|Respiratory Disease|Pulmonary Disease|COPD
Interventions: OTHER: Supervised Pulmonary Telerehabilitation|OTHER: Cognitive Telerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of ABT-493/ABT-530 in Adults With Chronic Hepatitis C Virus Genotype 4, 5, or 6 Infection (ENDURANCE-4)
Status: COMPLETED
Conditions: Hepatitis C Virus
Interventions: DRUG: ABT-493/ABT-530
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Family and Adolescent Motivational Incentives for Leveraging Youth
Status: COMPLETED
Conditions: Substance-Related Disorders
Interventions: BEHAVIORAL: Functional Family Therapy|BEHAVIORAL: Motivational Enhancement Tx/Cognitive Behavioral Tx|BEHAVIORAL: Contingency Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Keratin in Treating Radiation Dermatitis in Patients With Breast Cancer
Status: COMPLETED
Conditions: Breast Carcinoma|Radiation-Induced Dermatitis
Interventions: OTHER: Best Practice|OTHER: Quality-of-Life Assessment|DEVICE: Topical Keratin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Screening for Depression and Anxiety in Patients With Heart Disease
Status: COMPLETED
Conditions: Depression|Depressive Symptoms|Depressive Disorder|Anxiety|Anxiety Disorders|Panic Attacks|Heart Diseases|Collaboration
Interventions: BEHAVIORAL: Screening and counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study Of Eribulin (E7389) In Patients With Advanced Solid Tumors And Normal Or Reduced Hepatic Function As Per Child-Pugh System
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: E7389|DRUG: E7389|DRUG: E7389
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Electrical Stimulation Mediated Neuroplasticity: Lower Extremity CCNMES in Stroke
Status: COMPLETED
Conditions: Stroke|Hemiparesis|Footdrop
Interventions: DEVICE: Contralaterally Controlled Neuromuscular Electrical Stimulation|DEVICE: Cyclic Neuromuscular Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Adipokines and Fat Tissue in Psoriasis and Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriasis|Arthritic Psoriasis
Interventions: OTHER: bone densitometry|OTHER: questionnaires|OTHER: biological analyses
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing The Effect of Tadalafil 5 mg/Day to Sildenafil 25 mg/Day on Neutrophil-Lymphocyte and Platelet-Lymphocyte Ratios in Erectile Dysfunction Patients; and Comparison of Clinical Response
Status: UNKNOWN
Conditions: Erectile Dysfunction and Neutrophil Lymphocyte Ratio
Interventions: DRUG: Tadalafil 5mg/sildenafil 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Perconditioning in Patients With ST-segment Elevation Myocardial Infarction
Status: COMPLETED
Conditions: ST-segment Elevation Myocardial Infarction
Interventions: PROCEDURE: PPCI plus RIPC|PROCEDURE: PPCI only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medical Imaging and Thermal Treatment for Breast Tumors Using Harmonic Motion Imaging (HMI)
Status: RECRUITING
Conditions: Fibroadenoma|Breast Cancer Stage I
Interventions: PROCEDURE: Harmonic motion imaging guided focused ultrasound (HMIgFUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Combination of Telmisartan and Simvastatin in the Treatment of Hypertension and Hypercholesterolemia
Status: COMPLETED
Conditions: Hypertension|Dyslipidemias
Interventions: DRUG: telmisartan|DRUG: simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Parallel Group Study to Compare Sativex® With Placebo in the Treatment of Detrusor Overactivity in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Detrusor Overactivity|Multiple Sclerosis
Interventions: DRUG: Sativex®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Better Understanding Slow Language Impairment
Status: UNKNOWN
Conditions: Slow Language Impairment
Interventions: BEHAVIORAL: Evaluation of language skills and procedural learning of children with SLI and their controls. DNA sampling.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Dose-Finding Study of Topiramate (JNS019) in Participants With Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Topiramate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Timing of B and O Suppositories to Help Relieve Post-operative Bladder Spasms
Status: TERMINATED
Conditions: Overactive Bladder
Interventions: DRUG: Belladonna and Opium Suppository|PROCEDURE: Rectal Exam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Peri-Articular-Multimodal Drug and Oral Celecoxib in Management of Postoperative Pain of Total Knee Arthroplasty
Status: COMPLETED
Conditions: Postoperative Pain|Total Knee Arthroplasty
Interventions: DRUG: Multimodal Drug|DRUG: epinephrine|DRUG: celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: OPSCC N0 Nodal Control With Reduced IMRT
Status: TERMINATED
Conditions: Oropharyngeal Squamous Cell Carcinoma (OPSCCA)|HPV (Human Papillomavirus)-Associated
Interventions: RADIATION: 39.6 Gy radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radial Extracorporeal Shock Wave Treatment (rESWT) of Myofascial Pain Syndrome in Low Back Pain
Status: COMPLETED
Conditions: Myofascial Pain Syndromes|Low Back Pain|Lumbago
Interventions: DEVICE: Swiss DolorClast® CLASSIC applicator|DEVICE: Swiss DolorClast® CLASSIC placebo applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation/Expansion Study of MDK-703 in Patients With Advanced or Metastatic Solid Tumors
Status: TERMINATED
Conditions: Advanced or Metastatic Solid Tumors
Interventions: DRUG: MDK-703|DRUG: Checkpoint Inhibitor, Immune
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Pre-Loaded Betaine Supplementation on Thermoregulation and Exercise Metabolism in the Heat
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Betaine|DIETARY_SUPPLEMENT: BCAA Big 6|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Perioperative Imatinib Mesylate in Treating Patients With Locally Advanced Gastrointestinal Stromal Tumor
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumor
Interventions: DRUG: imatinib mesylate|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I BP Interferon (IFN) Beta-001
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Interferon beta-1a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TMTP1 Targeting Micro-metastasis LN in Laparoscopic SLN Detection in Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer|Sentinel Lymph Node
Interventions: PROCEDURE: ICG|PROCEDURE: ICG-CP|PROCEDURE: ICG-TMTP1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acupuncture on Craniomandibular Pain of Myofascial Origin.
Status: UNKNOWN
Conditions: Myofascial Pain|Craniofacial Pain
Interventions: DEVICE: real acupuncture|DEVICE: Placebo acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microperimetric Evaluation After Half-dose Photodynamic Therapy for Chronic Central Serous Chorioretinopathy
Status: COMPLETED
Conditions: Chronic Central Serous Chorioretinopathy
Interventions: PROCEDURE: half-dose photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Monoclonal Antibody Therapy in Treating Patients With Advanced Myeloid Cancer
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: BIOLOGICAL: filgrastim|DRUG: cytarabine|RADIATION: bismuth Bi213 monoclonal antibody M195
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Effectiveness of Bilateral Exablate Ablation of the Pallidothalamic Tract (PTT) for the Treatment of the Motor Complications of Parkinson's Disease (PD)
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DEVICE: Exablate 4000
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance Boosted Lopinavir Monotherapy Following Salvage Protease-inhibitor (PI) Based Regimen in HIV With Non-nucleoside Reverse Transcriptase Inhibitors (NNRTI) Based Regimen Failure
Status: COMPLETED
Conditions: HIV|AIDS|Lopinavir|Treatment Failure
Interventions: DRUG: Ritonavir-boosted lopinavir|DRUG: optimized background regimens (OBRs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Test Meal on Satiation Hormones in Obese and Normal Weight Adolescents
Status: COMPLETED
Conditions: Endocrine System Diseases
Interventions: DIETARY_SUPPLEMENT: test meal (500 kcal)|DIETARY_SUPPLEMENT: test meal (500 kcal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of GSK3915393 in Healthy Participants and to Evaluate the Interaction Between GSK3915393 and Grapefruit Juice and Itraconazole
Status: COMPLETED
Conditions: Celiac Disease|Coeliac Disease
Interventions: DRUG: GSK3915393 Capsules|DRUG: GSK3915393 Solution for Infusion|DRUG: Placebo capsules|DRUG: Itraconazole|OTHER: Water|OTHER: Grape fruit juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of TCIG vs ECIG in PLWH
Status: COMPLETED
Conditions: E Cigarette Use|Vaping|Smoking|Tobacco Smoking|Nicotine Use Disorder|Qt Interval, Variation in|HIV I Infection|Oxidative Stress|Inflammation
Interventions: OTHER: TCIG|OTHER: ECIG|OTHER: sham control
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: DAY101 vs. Standard of Care Chemotherapy in Pediatric Patients With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)
Status: RECRUITING
Conditions: Low-grade Glioma
Interventions: DRUG: Tovorafenib|DRUG: Chemotherapeutic Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quest to Analyze One Thousand Humans Meditating
Status: ENROLLING_BY_INVITATION
Conditions: Amyotrophic Lateral Sclerosis (ALS)|Angina, Stable|Anxiety|Asthma|Atrial Fibrillation|Cancer Brain|Cancer, Breast|Cancer Colon|Cancer, Lung|Cancer, Ovarian|Cancer Prostate|Cancer Skin|Throat Cancer|Lymphoma|Cancer, Thyroid|Cancer, Other|Cerebral Palsy|Chronic Fatigue Syndrome|Cluster Headache|Chronic Obstructive Pulmonary Disease (COPD)|Chronic Kidney Diseases|Crohn Disease|Deafness|Depression|Diabetes|Eczema|Epilepsy|Fibroids|Fibromyalgia|Heart Failure|Hypertension|Hyperthyroidism|Hypothyroidism|Irritable Bowel Syndrome (IBS)|Infertility|Lyme Disease|Macular Degeneration|Migraine|Multiple Allergies|Multiple Sclerosis|Osteoarthritis|Osteoporosis|Ovarian Cysts|Parkinson Disease|Phantom Limb Pain|Psoriasis|Post Traumatic Stress Disorder (PTSD)|Rheumatoid Arthritis|Sjogrens Disease|Spinal Cord Injury|Spinal Stenosis|Stroke|Tension Headache|Tinnitus|Ulcerative Colitis
Interventions: BEHAVIORAL: Advanced multi-component meditation practice
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Effects of NMRA-323511 Among Healthy Elderly and Adults With Agitation Associated With Dementia Due to Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer's Disease|Healthy Elderly
Interventions: DRUG: NMRA-323511|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Nilotinib in Patients With a Chronic Disease of the Graft Against the Host
Status: COMPLETED
Conditions: Graft Versus Host Disease
Interventions: DRUG: Imatinib Mesylate and Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supine Positioning for Graft Attachment After Descemet Membrane Endothelial Keratoplasty
Status: COMPLETED
Conditions: Fuchs' Endothelial Dystrophy
Interventions: BEHAVIORAL: Supine positioning: 5 days|BEHAVIORAL: Supine positioning: 1 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Balloon-Expandable Stent Versus Self-Expandable Stent for the Atherosclerotic ILIAC Arterial Disease
Status: COMPLETED
Conditions: Peripheral Artery Disease|Atherosclerosis
Interventions: DEVICE: Balloon expandable stent|DEVICE: Self expandable stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CSE for Labour Analgesia: A Comparison of Two Intrathecal Regimens
Status: COMPLETED
Conditions: Labor Pain
Interventions: DRUG: Bupivacaine-fentanyl|DRUG: Bupivacaine-fentanyl morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BIO 300 Oral Suspension in Previously Hospitalized Long COVID Patients
Status: RECRUITING
Conditions: COVID-19|Long COVID|Pulmonary Fibrosis|Post-acute Respiratory Complications of COVID-19
Interventions: DRUG: BIO 300 Oral Suspension|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STEMI Cool Pilot Trial to Assess Cooling as an Adjunctive Therapy to PCI In Patients With Acute MI (Phase A)
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: Cooling Procedure using the ZOLL Thermogard XP3 IVTM System|DEVICE: PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double-blind, Randomized Comparative Cross-sectional Study of Pharmacodynamics and Pharmacokinetics of Drugs GP40141
Status: RECRUITING
Conditions: Pharmacodynamics|Pharmacokinetics|Bioequivalence
Interventions: DRUG: GP40141|DRUG: Nplate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Kinesiotape on Balance in With Multiple Sclerosis
Status: UNKNOWN
Conditions: Individuals With Multiple Sclerosis|With Ataxia Symptoms|No Secondary Disease Affecting Balance
Interventions: OTHER: Kinesiotape
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Immunogenicity Study of Candidate HIV-1 Vaccine Given to Healthy Infants Born to HIV-1-infected Mothers
Status: UNKNOWN
Conditions: HIV-1|HIV Infections
Interventions: BIOLOGICAL: MVA.HIVA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Effect of Hydrogen Water in Oral Mucositis in Head and Neck Cancer Patients After Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer|Oral Mucositis|Pain|Quality of Life
Interventions: OTHER: hydrogen water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Randomized Trial of Two Regimens of Misoprostol for Second Trimester Termination for Intrauterine Fetal Death
Status: TERMINATED
Conditions: Labor Induction
Interventions: DRUG: Misoprostol|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Dosage of Ticagrelor in Korean Patients With AMI
Status: UNKNOWN
Conditions: Acute Myocardial Infarction|Ticagrelor
Interventions: DRUG: Clopidogrel 75 mg|DRUG: Ticagrelor 60mg|DRUG: Ticagrelor 45 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Milk Peptides on Postprandial Blood Glucose Profile
Status: COMPLETED
Conditions: Postprandial Hyperglycemia
Interventions: DIETARY_SUPPLEMENT: Low dose milk peptide|DIETARY_SUPPLEMENT: High Dose milk peptide|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Helicobacter Pylori Eradication Therapy for Epileptic Children
Status: COMPLETED
Conditions: Epilepsy, Generalized|Helicobacter Pylori Infection
Interventions: DRUG: Triple therapy for H. pylori infection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Otamixaban Versus Unfractionated Heparin (UFH) and Eptifibatide in Non-ST Elevation Acute Coronary Syndrome
Status: COMPLETED
Conditions: Coronary Disease
Interventions: DRUG: Otamixaban (XRP0673)|DRUG: unfractionated heparin|DRUG: eptifibatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of Two Iron Compounds for Treatment of Anemia in Hemodialysis Patients
Status: COMPLETED
Conditions: Anemia of Chronic Kidney Disease
Interventions: DRUG: Supplementation of ferric carboxymaltose|DRUG: Supplementation of iron sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tofacitinib for Reduction of Spinal Inflammation in Patients With Psoriatic ArthritiS PresenTing With Axial InvOlvement
Status: UNKNOWN
Conditions: Psoriatic Arthritis|Spondylitis|Sacroilitis
Interventions: DRUG: Tofacitinib 5 MG Oral Tablet [Xeljanz]|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: In Vivo Sun Protection Factor Determination
Status: COMPLETED
Conditions: Skin Care
Interventions: OTHER: Negative Control|OTHER: Positive Control|OTHER: Test Product A|OTHER: Test Product B|OTHER: Test Product C|OTHER: Test Product D|OTHER: Test Product E|OTHER: Test Product F|OTHER: Test Product G|OTHER: Test Product H
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chemotherapy and Rituximab With or Without Total-Body Irradiation and Peripheral Stem Cell Transplant in Treating Patients With Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: ifosfamide|DRUG: prednisone|DRUG: vincristine sulfate|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Axillary Brachial Plexus Block Using 0.25% Bupivacaine Versus Using 0.19%Bupivacaine in Pediatrics
Status: COMPLETED
Conditions: Acute Postoperative Pain|Motor Activity
Interventions: PROCEDURE: 0.25%Bupivacaine Axillary brachial plexus block|PROCEDURE: 0.19% Bupivacaine Axillary brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sentinel Node in Endometrial Cancer
Status: RECRUITING
Conditions: Endometrial Cancer
Interventions: DIAGNOSTIC_TEST: injection via TUMIR of the tracer [99mTc] Tc-albumin nanocoloid-ICG (6 mCi, 4 ml)|DIAGNOSTIC_TEST: injection via TUMIR of [99mTc] Tc-albumin nanocoloid (6mCi, 8ml).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study of Azacitidine Combined With Homoharringtonie Based Regimens in AML
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Homoharringtonine|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Double-Blind, Randomized, Controlled Study to Evaluate the Safety and Efficacy of RUT058-60
Status: TERMINATED
Conditions: Postoperative Wound Infection-deep|Post Operative Wound Infection
Interventions: DRUG: RUT058-60|DRUG: Sterile saline for irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Ixekizumab (LY2439821) in Participants With Active Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: Placebo|DRUG: Ixekizumab 80 mg Q4W|DRUG: Ixekizumab 80 mg Q2W
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose Dexmedetomidine and Postoperative Delirium After Cardiac Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiac Surgery|Cardiopulmonary Bypass|Dexmedetomidine|Delirium|Survival
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Inform and Reduce Pre-surgical Anxiety of the Child and His Parents: Interest of an Explanatory Movie.
Status: COMPLETED
Conditions: Anxiety Linked to the Surgery and / or Anesthesia
Interventions: OTHER: Movie
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial of YYD302 for Treatment of Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: YYD302 2ml|DRUG: YYD302 3ml|DRUG: Placebo 3ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ⅲ Trial of WBRT Versus Erlotinib Concurrent Whole-brain Radiation Therapy as ﬁrst-line Treatment for Patients With Multiple Brain Metastases From Non-small-cell Lung Cancer(ENTER): a Multicentre, Open-label, Randomised Study
Status: COMPLETED
Conditions: Multiple Brain Metastases|Non-small-cell Lung Cancer
Interventions: DRUG: Erlotinib|DRUG: WBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of an IGRA Test for the Diagnosis of Active and Latent Tuberculosis
Status: RECRUITING
Conditions: TUBERCULOSIS
Interventions: DIAGNOSTIC_TEST: test IGRA|DIAGNOSTIC_TEST: TEST QUATIFERON TB Gold Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Musculoskeletal Plasticity After Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: BEHAVIORAL: Single-session electrically induced exercise|BEHAVIORAL: Electrically-induced exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stress Echo 2020 - The International Stress Echo Study
Status: UNKNOWN
Conditions: Coronary Artery Disease|Heart Failure|Hypertrophic Cardiomyopathy|Aortic Valve Disease|Athletes Heart|Tetralogy of Fallot|Pulmonary Arterial Hypertension
Interventions: PROCEDURE: Left ventricular contractile reserve SE|PROCEDURE: B-lines SE|PROCEDURE: Left ventricular outflow tract gradient SE|PROCEDURE: Diastolic function SE|PROCEDURE: Mitral regurgitation SE|PROCEDURE: Pulmonary hemodynamics SE|PROCEDURE: Coronary flow reserve SE
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Flow Nasal Cannula Therapy in Bronchiolitis : Early vs Rescue
Status: UNKNOWN
Conditions: Bronchiolitis|Respiratory Syncytial Virus (RSV)
Interventions: DEVICE: Heated Humidified High Flow Nasal Cannula|DEVICE: Standard Therapy (Low Flow Nasal Cannula)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE