pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Nursing Led Interdisciplinary Intervention in Prevention of Girl Child Mortality and Maltreatment
Status: COMPLETED
Conditions: Abuse Neglect Social|Deprivation, Maltreatment Syndrome (Infant or Child)
Interventions: BEHAVIORAL: Family Counselling and safeguarding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Collection of Sequential Samples From Patients With Malignant Myeloid Hemopathy for the Study of Treatment Resistance
Status: NOT_YET_RECRUITING
Conditions: Hematologic Cancer
Interventions: OTHER: experimental:Acute leukemia/myelodysplastic or myeloproliferative disease
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Serelaxin Versus Standard of Care in Acute Heart Failure (AHF) Patients
Status: TERMINATED
Conditions: Acute Heart Failure (AHF)
Interventions: DRUG: Serelaxin|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture at the Sphenopalatine Ganglion in the Treatment of Moderate-to-severe Seasonal Allergic Rhinitis
Status: RECRUITING
Conditions: Seasonal Allergic Rhinitis
Interventions: OTHER: Acupuncture group|OTHER: Placebo acupuncture group|OTHER: Rescue medication group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Partnership-Project - Reinforcing Partnership Between Cancer Patient, General Practitioner and Oncologist During Chemotherapy
Status: COMPLETED
Conditions: Cancer
Interventions: OTHER: Shared video consultation between patient, general practitioner and oncologist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Mindfulness Oriented Recovery Enhancement for Chronic Pain and Opioid Relapse
Status: COMPLETED
Conditions: Opioid Use|Chronic Pain
Interventions: BEHAVIORAL: Mindfulness Oriented Recovery Enhancement|OTHER: Methadone Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Total Neoadjuvant Therapy Combined With Tislelizumab for Local Advanced of Middle and Low Rectal Cancer
Status: RECRUITING
Conditions: Locally Advanced Rectal Cancer
Interventions: COMBINATION_PRODUCT: Long-course chemoradiation, with Tislelizumab (PD-1 inhibitor)|COMBINATION_PRODUCT: Long-course chemoradiation, without Tislelizumab (PD-1 inhibitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EPIgenetics and in Vivo Resistance of Chronic Myeloid Leukemia Stem Cells to Tyrosine Kinase Inhibitors
Status: RECRUITING
Conditions: Chronic Myeloid Leukemia (CML)|Chronic Phase
Interventions: BIOLOGICAL: Collection of blood and bone marrow
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Clinical Effect Between Endoscopic and Microscopic Ear Surgery of Cholesteatoma: A Multicenter Retrospective Observational Study
Status: COMPLETED
Conditions: Endoscopy; Microscopy; Ear Surgery; Cholesteatoma; Clinical Effect
Interventions: PROCEDURE: endoscopic ear surgery|PROCEDURE: microscopic ear surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Postoperative Pain After Gallbladder Retrieval From Umbilical and Epigastric Ports.
Status: COMPLETED
Conditions: Cholelithiasis
Interventions: PROCEDURE: Laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Medical Economic Evaluation and of Quality of Life of the Kidney Living Donors.
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: PROCEDURE: open donor nephrectomy|PROCEDURE: standard and hand-assisted laparoscopic donor nephrectomy|PROCEDURE: laparoscopic robotic-assisted nephrectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Telmisartan 80 mg/HCTZ 12.5 mg and Telmisartan 40 mg/HCTZ 12.5 mg in Patients With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan 40 mg/HCTZ 12.5 mg|DRUG: Telmisartan 40 mg|DRUG: Telmisartan 80 mg/HCTZ 12.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Electrical Stimulation-Assisted Walking: Reduction of Secondary Complications Due to Spinal Cord Injury
Status: UNKNOWN
Conditions: Spinal Cord Injury
Interventions: DEVICE: Compex Motion Stimulator|DEVICE: Compex Motion Stimulator|OTHER: Conventional Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suitability of a Low Dose Lipopolysaccharide (LPS) Inhalation as a Challenge Model
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LPS challenge with nebulized LPS|DRUG: fluticasone propionate (FP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Cariprazine for Bipolar I Disorder
Status: COMPLETED
Conditions: Mania|Bipolar I Disorder
Interventions: DRUG: Cariprazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Anti-gravity Treadmill Training on Knee Osteoarthritis in Geriatric Population.
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: DEVICE: Anti gravity treadmill training|PROCEDURE: Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MitraClip® and Hemodynamic Effects of Relevant Iatrogenic Atrial Septum Defect Closure
Status: UNKNOWN
Conditions: Mitral Valve Insufficiency|Heart Septal Defects, Atrial
Interventions: DEVICE: Figulla Flex Occluder (Occlutech)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Periodontal Condition in Pregnancy and Low Birth Delivery Incidence
Status: COMPLETED
Conditions: Pregnancy|Birth Weight|Periodontal Diseases
Interventions: OTHER: collection of periodontal records|OTHER: pregnancy parameters|OTHER: Initial Periodontal Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Individualized Exercise Guidance on Pregnancy Outcome
Status: COMPLETED
Conditions: Pregnancy Outcome|Gestational Weight Gain|Mediation|Macrosomia, Fetal
Interventions: BEHAVIORAL: Individualized exercise guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Contact Force Guided Ablation Versus Conventional Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Improving Outcome After Pulmonary Vein Isolation
Interventions: OTHER: Pulmonary vein isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Administered Via the Sofusa® DoseConnect™ in Patients With Relapsed/Refractory Cutaneous T-cell Lymphoma.
Status: RECRUITING
Conditions: Mycosis Fungoides
Interventions: COMBINATION_PRODUCT: Pembrolizumab administered using the Sofusa® DoseConnect™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Multicentre, Randomized, Controlled, Cross-over Study on the Safety and Performance of the Biologic Fusion Option of DialogiQ Compared to Haemodialysis Without Biologic Fusion in Hypotension Prone Patients on Maintenance Haemodialysis
Status: RECRUITING
Conditions: Renal Dialysis
Interventions: DEVICE: BioLogic Fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CTH120 First-in-Human Study: Single and Multiple Ascending Doses and Potential Food Interaction
Status: RECRUITING
Conditions: Fragile X Syndrome
Interventions: DRUG: CTH120|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ascorbic Acid for Prevention of Colistin-Associated Nephrotoxicity
Status: UNKNOWN
Conditions: Drug Safety
Interventions: DRUG: Colistin|DRUG: Colistin + Ascorbic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Role of Uterotonics in Reducing Intraoperative Blood Loss in Patients With PASD Undergoing Cesarean Hysterectomy
Status: RECRUITING
Conditions: Placenta Accreta Spectrum
Interventions: DRUG: oxytocin|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of Preheated and Repeated Preheated Versus Conventional Bulk Fill Resin Composite
Status: COMPLETED
Conditions: Dental Leakage
Interventions: OTHER: preheated conventional bulk-fill resin composite, X-tra fill (VOCO, GERMANY) at 68◦C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the Influence of Prophylactic and Empirical Anti-fungal Treatment in Severe Sepsis Patients With Perforations
Status: COMPLETED
Conditions: Intra-abdominal Perforation
Interventions: DRUG: fluconazole and caspofungin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Preoperative Oral Tramadol on Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis
Status: COMPLETED
Conditions: Symptomatic Irreversible Pulpitis
Interventions: DRUG: TraMADol 50 Mg Oral Tablet|DRUG: Tramadol 100 MG Oral Tablet|DRUG: Ibuprofen 600Mg Tab|DRUG: ibuprofen 600 mg/acetaminophen 1000 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Exploration for Pharmacodynamics and Pharmacokinetics of YH4808 New Formulation in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: YH4808 NF 100|DRUG: YH4808 OF 200|DRUG: YH4808 NF 200|DRUG: YH4808 NF 400
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Tolerability and Risk of Adverse Events With a Probiotic Supplement
Status: COMPLETED
Conditions: Healthy Individuals
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: High dose F. prausnitzii and D. piger|DIETARY_SUPPLEMENT: Low dose F. prausnitzii and D. piger
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Miltefosine (Long Course) for Bolivian Mucosal Leishmaniasis
Status: COMPLETED
Conditions: Leishmaniasis
Interventions: DRUG: miltefosine: 2.5 mg/kg/day for 42 days
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Ocular Graft-versus-Host Disease (GVHD) With Topical Loteprednol Etabonate 0.5%
Status: COMPLETED
Conditions: Dry Eyes
Interventions: DRUG: Lotemax|DRUG: Restasis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Open-label Single Dose Randomized, Parallel Group Study Followed by Single-blind Repeat Dosing, to Compare the Relative Bioavailability of GSK2212836.
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: GSK2212836|DRUG: GSK2212836
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin Hydrochloride, Cyclophosphamide, Docetaxel, and S-1 Before Surgery in Treating Women With Stage II or Stage III Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: cyclophosphamide|DRUG: docetaxel|DRUG: doxorubicin hydrochloride|DRUG: tegafur-gimeracil-oteracil potassium|PROCEDURE: neoadjuvant therapy|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Citric Acid Demineralization on Autogenous Bone Blocks Consolidation in Humans
Status: COMPLETED
Conditions: Alveolar Bone Atrophy|Bone Resorption
Interventions: PROCEDURE: Control|PROCEDURE: Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of REPotrectinib With or Without Fulvestrant in Patients With Hormone Receptor-positive Human Epidermal Growth Factor 2-negative Metastatic Invasive LObular Carcinoma Who Received a Prior Endocrine Therapy in Combination With Cyclin-dependent Kinase 4 and 6 Inhibitor (REPLOT Trial)
Status: RECRUITING
Conditions: Hormone Receptor-positive Human Epidermal Growth Factor 2-negative|Metastatic Invasive LObular Carcinoma
Interventions: DRUG: Fulvestrant|DRUG: Repotrectinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Accuracy of Rapid Molecular Tests for Group A Streptococcal Pharyngitis Using Saliva Samples
Status: RECRUITING
Conditions: Streptococcal Pharyngitis
Interventions: DIAGNOSTIC_TEST: Index test: Abbott ID NOW STREP A 2|DIAGNOSTIC_TEST: Reference standard test: Composite of culture and PCR-based tests based on a throat swab|DIAGNOSTIC_TEST: Comparator test: Rapid antigen detection test (usual care)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Evaluate the Efficacy and Safety of TG-1000 Compared With Placebo in Adult Patients With Acute Uncomplicated Influenza Virus Infection
Status: COMPLETED
Conditions: Influenza Virus Infection
Interventions: DRUG: TG-1000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Applied Forces During Neonatal Intubation
Status: COMPLETED
Conditions: Intubation|Training|Neonate|Manikin
Interventions: PROCEDURE: Intubation with traditional laryngoscope|PROCEDURE: Intubation with a straight blade video laryngoscope|PROCEDURE: Intubation with a hyper-angulated video laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Fatty Acid Levels and Growth in Infants Fed Amino Acid Based (AA) Formulas
Status: WITHDRAWN
Conditions: Cow's Milk Allergy|Intolerance to Extensively Hydrolyzed Formulas|Intolerance to Breast Milk
Interventions: OTHER: Amino Acid-based Formula with high DHA and ARA|OTHER: Amino Acid-based Formula with lower DHA and ARA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Assess the Efficacy and Safety of AXS-02 in Subjects With Knee OA Associated With Bone Marrow Lesions
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DRUG: AXS-02|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Norovirus Challenge Study
Status: COMPLETED
Conditions: Norovirus Infections
Interventions: BIOLOGICAL: VXA-G1.1-NN|OTHER: Placebo Tablets|BIOLOGICAL: Norovirus GI.1 Norwalk Virus Inoculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: SaCoVLM™ Video Laryngeal Mask Versus LMA Supreme
Status: RECRUITING
Conditions: Anesthesia|Airway
Interventions: DEVICE: SaCoVLM™ video laryngeal mask|DEVICE: LMA Supreme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adjunctive Withania Somnifera (Ashwagandha) for Persistent Symptoms in People With Schizophrenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: WSE|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Rivaroxaban in Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Anemia|Sickle Cell-Beta0-Thalassemia
Interventions: DRUG: rivaroxaban|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post Operative Pain Management for ACL Reconstruction
Status: ENROLLING_BY_INVITATION
Conditions: Pain, Postoperative
Interventions: DRUG: Bupivacaine HCl 0.5% Injectable Solution|DRUG: Dexamethasone|PROCEDURE: Infiltration between Popliteal Artery and Capsule of the knee (iPACK)|DRUG: Percocet 5Mg-325Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Vitamin B3 Derivative to Treat Mitochondrial Myopathy
Status: RECRUITING
Conditions: Mitochondrial Myopathy
Interventions: DIETARY_SUPPLEMENT: Nicotinamide Riboside|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Clinical Study of PET Scanning in Evaluation of Vaccine Reactogenicity
Status: COMPLETED
Conditions: Positron-Emission Tomography|Immunization Reaction
Interventions: BIOLOGICAL: Immunization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Aprepitant or Ondansetron in Treating Nausea and Vomiting Caused By Opioids in Patients With Cancer
Status: WITHDRAWN
Conditions: Myeloproliferative Disorders|Leukemia|Lymphoma|Lymphoproliferative Disorder|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Nausea and Vomiting|Solid Tumor
Interventions: DRUG: aprepitant|DRUG: ondansetron hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Application of Preoperative Axillary Lymph Node Marking With Nano-Carbon in Breast Cancer Patients Before Neoadjuvant Chemotherapy
Status: UNKNOWN
Conditions: Breast Cancer|Neoadjuvant Therapy|Sentinel Lymph Node Biopsy
Interventions: DRUG: carbon dye
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TPI 287 in Patients With Refractory or Recurrent Neuroblastoma or Medulloblastoma
Status: COMPLETED
Conditions: Neuroblastoma|Medulloblastoma|Relapse
Interventions: DRUG: TPI 287
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Insulin Peglispro With Insulin Glargine as Basal Insulin Treatment
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin Peglispro|DRUG: Insulin Glargine|DRUG: Oral Antihyperglycemic Medications (OAMs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Extracorporeal Magnetic Stimulation, Pelvic Floor Muscle Exercise, and Combination of Both in Management of Post Radical Prostatectomy Urinary Incontinence
Status: RECRUITING
Conditions: Post Radical Prostatectomy Urinary Incontinence
Interventions: DEVICE: Extracorporeal electromagnetic stimulation|BEHAVIORAL: Pelvic floor exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GVM±R in Patients With Relapsed or Refractory Aggressive NHL.
Status: RECRUITING
Conditions: Peripheral T Cell Lymphoma|Diffuse Large B-cell Lymphoma
Interventions: DRUG: GVM±R regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ability Of ([18F]-AV-45) PET Scan to Distinguish Alzheimer's Disease Subjects From Cognitively Normal Individuals
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: florbetapir F 18|DRUG: [11C]-PIB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Trial of Trilaciclib, Pembrolizumab, Gemcitabine and Carboplatin in Metastatic Triple-Negative Breast Cancer
Status: RECRUITING
Conditions: Metastatic Triple-Negative Breast Cancer
Interventions: DRUG: Trilaciclib|DRUG: Pembrolizumab|DRUG: Gemcitabine|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Study Evaluating the Effect of Givinostat in Patients With Chronic Myeloproliferative Neoplasms
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Myeloproliferative Neoplasms
Interventions: DRUG: givinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of THE-630 in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)
Status: TERMINATED
Conditions: Gastrointestinal Stromal Tumors (GIST)|Neoplasms, Connective Tissue|Neoplasms, Connective and Soft Tissue|Neoplasms by Histologic Type|Neoplasms|Gastrointestinal Neoplasms|Digestive System Neoplasm|Digestive System Disease|Gastrointestinal Diseases
Interventions: DRUG: THE-630
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Compare the Pharmacokinetic Characteristics of CKD-395 0.5/1000 mg in Healthy Male Volunteers
Status: COMPLETED
Conditions: Diabetes Mellitus, Type II
Interventions: DRUG: Duvie Tab. 0.5mg, Glucophage XR Tab. 1000mg|DRUG: CKD-395 0.5/1000mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Pariet to Prevent Gastric and Duodenal Ulcer Associated With Low-aspirin in Korean Participants With a History of Gastric and Duodenal Ulcer
Status: COMPLETED
Conditions: Stomach Ulcer|Duodenal Ulcer
Interventions: DRUG: Pariet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Cohort Study on the Prognosis of Neonatal KCNQ2 Gene-associated Epileptic Encephalopathy
Status: RECRUITING
Conditions: Seizures|Seizure Disorder|Seizure Newborn|Seizures, Generalized|Epileptic Encephalopathy|Epileptic Encephalopathy, Neonatal-onset|Epileptic Encephalopathy, Infant-onset|KCNQ2
Interventions: GENETIC: KCNQ2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Etco2 Levels on the End-tidal Concentration of Sevoflurane
Status: COMPLETED
Conditions: End-tidal Sevoflurane|End-tidal Carbon Dioxide|Minimum Alveolar Concentration
Interventions: PROCEDURE: low etco2|PROCEDURE: normal etco2|PROCEDURE: high etco2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacological vs Surgical Treatment for Mixed Incontinence
Status: WITHDRAWN
Conditions: Mixed Urinary Incontinence|Urinary Incontinence, Stress|Urinary Incontinence, Urge
Interventions: DRUG: Tolterodine|PROCEDURE: tension free vaginal tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TCR Modified T Cells MDG1011 in High Risk Myeloid and Lymphoid Neoplasms
Status: TERMINATED
Conditions: Safety|Tolerability|Feasibility|Treatment Efficacy
Interventions: DRUG: MDG1011|OTHER: Investigator Choice therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerance and Pharmacokinetics of Raltegravir-Containing Antiretroviral Therapy in Infants, Children Infected With HIV and TB
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: Raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Selective Inhibition of Cholesterol Absorption With Ezetimibe on Intestinal Cholesterol Homeostasis in Dyslipidemic Men With Insulin-resistance - a Pilot Study
Status: COMPLETED
Conditions: Metabolic Syndrome X
Interventions: DRUG: Ezetimibe|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VCRC Tissue Repository
Status: RECRUITING
Conditions: Aortitis|Cutaneous Vasculitis|Eosinophilic Granulomatosis With Polyangiitis|Giant Cell Arteritis|Granulomatosis With Polyangiitis (Wegener's)|Henoch-Schonlein Purpura|IgA Vasculitis|Microscopic Polyangiitis|Polyarteritis Nodosa|Takayasu Arteritis|Churg-Strauss Syndrome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The PUPIL Study - Automated, Quantitative Pupil Assessment Using Binocular OCT
Status: COMPLETED
Conditions: Healthy Volunteers|Relative Afferent Pupil Defect|Pupil Anomaly
Interventions: DEVICE: Binocular OCT prototype|DEVICE: Konan RAPDx
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study in Hormone Receptor-positive Metastatic Breast Carcinoma Patients to Test a New Schedule of Efti (IMP321, Eftilagimod Alpha) as Adjunctive to a Weekly Treatment Regimen of Paclitaxel
Status: WITHDRAWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Eftilagimod Alpha|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Engaging Mobile Prism Adaptation Treatment at Home
Status: ACTIVE_NOT_RECRUITING
Conditions: Spatial Neglect
Interventions: BEHAVIORAL: Prism Adaptation - 15-degree prism goggles|OTHER: Prism Adaptation - 5-degree prism goggles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Osteoporosis Prevention With Low Dose Alendronate
Status: COMPLETED
Conditions: Osteopenia
Interventions: DRUG: alendronate|DIETARY_SUPPLEMENT: Calcium/Vitamin D|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: NightCAP: Reducing Hypnotic Drug Use and Improving Night-time Care
Status: UNKNOWN
Conditions: Dementia
Interventions: BEHAVIORAL: Hypnotic Medication Review|BEHAVIORAL: Structured Sleep Hygiene|BEHAVIORAL: Night Time Care Activities Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Photobiomodulation as a Preventive Treatment for Diabetic Foot
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot
Interventions: DEVICE: Photobiomodulation|DEVICE: Simulation of Photobiomodulation|BEHAVIORAL: Therapeutic education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Clinical Trial Using Amniotic Membrane in Robotic Assisted Laparoscopic Prostatectomy
Status: COMPLETED
Conditions: Pudendal Nerve
Interventions: PROCEDURE: Robotic Assisted Laparoscopic Prostatectomy|OTHER: Application of Absorbable Hemostat|OTHER: Application of dehydrated human amniotic membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LC Bead LUMI Radio-Opaque Embolic Beads to Detect and Characterize the Vascularity of Hepatic Tumors
Status: TERMINATED
Conditions: Hepatic Cancer|Liver Neoplasms|Hepatocellular Cancer|Liver Cancer
Interventions: PROCEDURE: Transarterial embolization (TAE)|DEVICE: LC Bead LUMI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: SHOrt-term Glycemic Control for Reducing Post-SURGical Complications
Status: NOT_YET_RECRUITING
Conditions: Diabetes|Uncontrolled Diabtetes
Interventions: OTHER: Short-term glycemic control group|OTHER: Standard-of-care group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Conditioning on Myocardial Damage in STEMI
Status: COMPLETED
Conditions: ST-elevation Myocardial Infarction
Interventions: DEVICE: Combined intrahospital pre- and postconditioning|DEVICE: Postconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of BBI-4000 Gel in Patients With Axillary Hyperhidrosis
Status: COMPLETED
Conditions: Primary Axillary Hyperhidrosis
Interventions: DRUG: Sofpironium Bromide Gel, 5%|DRUG: Sofpironium Bromide Gel, 15%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed Plus Cisplatin Bi-Weekly, in Patients With Urothelial Cancer (Metastatic, Locally Advanced or Non-Resectable)
Status: COMPLETED
Conditions: Urologic Neoplasms
Interventions: DRUG: pemetrexed|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability and Efficacy of TMC435 Along With Pegylated Interferon Alpha-2a (Pegasys) and Ribavirin (Copegus) Triple Therapy in Chronic Hepatitis C Genotype-1 Infected Patients Co-infected With Human Immunodeficiency Virus-Type 1
Status: COMPLETED
Conditions: Hepatitis C Virus Genotype-1
Interventions: DRUG: TMC435|DRUG: Pegylated interferon alpha-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Infraclavicular Brachial Plexus Block Using Levo-bupivacaine Alone or Combined With Dexmedetomidine for Hand and Forearm Surgeries
Status: COMPLETED
Conditions: Acquired Deformity of Elbow|Forearm|Hand|Wrist
Interventions: DRUG: Levobupivacaine(chirocaine) plus dexmedetomidine(precedex)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: COVID-19 Prevention Trial: Effect of Prophylactic Use of TAFFIX™ on Infection Rate by SARS-CoV-2 Virus (COVID-19).
Status: COMPLETED
Conditions: COVID-19|Upper Respiratory Tract Infections
Interventions: DEVICE: TaffiX™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Economic Evaluation of a Multistage Shared Decision-making Program for Type 2 Diabetes: a Pilot Study
Status: ENROLLING_BY_INVITATION
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: multistage shared decision-making program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Axial Ablation Versus Terminal Interruption of the Reflux Source
Status: UNKNOWN
Conditions: Venous Ulcer
Interventions: PROCEDURE: Terminal Interruption of the Reflux Source|PROCEDURE: Axial Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Relapse Prevention of Treatment-Resistant Depression
Status: COMPLETED
Conditions: Treatment Resistant Depression
Interventions: DRUG: Olanzapine and Fluoxetine combination (OFC)|DRUG: Fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of VIRAZOLE® in Hospitalized Adult Participants With Respiratory Distress Due to COVID-19
Status: COMPLETED
Conditions: COVID19
Interventions: DRUG: 50 mg/mL Virazole|DRUG: 100 mg/mL Virazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of TX Regimen as First-line Treatment for Asian Elderly Patients With Advanced Adenocarcinoma of Lung
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: erlotinib in combination with capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Connecting Healthy Women: Examining the Effect of an Intervention From the Effect of Being Reachable
Status: COMPLETED
Conditions: Contraception|Sexually Transmitted Infections|Cervical Cancer
Interventions: BEHAVIORAL: Community health worker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of the Panax Ginseng + Associations to Ginkgo Biloba in the Treatment of Cognitive Function Disorders
Status: WITHDRAWN
Conditions: Memory Deficit
Interventions: DRUG: Panax Ginseng + Ginkgo Biloba + Polyminerals + Multivitamin|DRUG: Ginkgo Biloba (Tebonin®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter, Randomized, Open Label, Parallel Study to Evaluate the Efficacy & Safety of IVF-M HP Inj. vs. Menopur® Inj.
Status: COMPLETED
Conditions: Infertility, Female
Interventions: DRUG: IVF-M HP Inj.|DRUG: Menopur® Inj.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin A Single Blind Split-Face Randomized Pilot Study
Status: COMPLETED
Conditions: Facial Rhytids
Interventions: DRUG: onabotulinumtoxinA|DRUG: abobotulinumtoxinA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bortezomib and Paclitaxel in Treating Patients With Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: bortezomib|DRUG: paclitaxel|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Versus Ketamine Versus Midazolam in Endoscopic Procedures
Status: COMPLETED
Conditions: Sedation and Analgesia
Interventions: DRUG: Dexmedetomidine|DRUG: Ketamine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetic Characteristics Evaluation on DA414
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: DRUG: DA414 Granules|DRUG: DA414 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of an Electronic Reminder System on Direct Oral Anticoagulant and Oral Diabetes Medication Adherence
Status: UNKNOWN
Conditions: Anticoagulant Drugs|Diabetes Mellitus, Type 2
Interventions: DEVICE: Electronic medicine reminder system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Change in Disease State and Adverse Events in Adult Participants With Polymyalgia Rheumatica (PMR) Dependent on Glucocorticoid Treatment, Receiving Subcutaneous Injections of ABBV-154
Status: TERMINATED
Conditions: Polymyalgia Rheumatica
Interventions: DRUG: ABBV-154|DRUG: Placebo|DRUG: Glucocorticoid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Aerosolized Liposomal 9-Nitro-20 (S)- Camptothecin (L9NC)
Status: COMPLETED
Conditions: Lung Diseases|Cancer
Interventions: DRUG: Liposomal 9-Nitrocamptothecin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study of Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy Previously Enrolled in PIONEER
Status: COMPLETED
Conditions: Hypertrophic Cardiomyopathy
Interventions: DRUG: mavacamten
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Crossover Bioequivalence Study of Intravenously Administered ATI0918 and DOXIL/CAELYX in Patients With Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer|Malignant Female Reproductive System Neoplasm|Cancer|Ovarian Tumor|Ovarian Epithelial Cancer Recurrent
Interventions: DRUG: DOXIL/CAELYX|DRUG: ATI-0918
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MK0782 + Low-Dose Aspirin 7-Day Erosion Endoscopy Study (0782-001)
Status: COMPLETED
Conditions: Stomach Ulcer|Duodenal Ulcer
Interventions: DRUG: MK0782
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Norfloxacin With Itopride Versus Norfloxacin in Secondary Prophylaxis of Spontaneous Bacterial Peritonitis
Status: RECRUITING
Conditions: Spontaneous Bacterial Peritonitis
Interventions: DRUG: Norfloxacin|DRUG: Itopride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neuromuscular Electrical Stimulation Superimposed or Not on Voluntary Contraction After Reconstruction of the Anterior Cruciate Ligament: a Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Anterior Cruciate Ligament Reconstruction Rehabilitation|Anterior Cruciate Ligament Reconstruction
Interventions: DEVICE: Neuromuscular electrical stimulation|DEVICE: Neuromuscular electrical stimulation with superimposed voluntary contraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Liposomal Bupivacaine Post Septorhinoplasty
Status: ENROLLING_BY_INVITATION
Conditions: Rhinoplasty|Pain Management
Interventions: DRUG: Liposomal Bupivacaine|DRUG: 0.25% bupivacaine with 1:200,000 epinephrine|OTHER: Placebo - Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of BMS-224818 (Belatacept) in Patients Who Have Undergone a Kidney Transplant and Are Currently on Stable Cyclosporine or Tacrolimus Regimen With or Without Corticosteroids
Status: COMPLETED
Conditions: Renal Transplant
Interventions: DRUG: Belatacept|DRUG: Cyclosporine A|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Acute Bronchitis With Pelargonium Sidoides Extract
Status: ENROLLING_BY_INVITATION
Conditions: Acute Bronchitis
Interventions: OTHER: Pelargonium sidoides extract EPs® 7630|OTHER: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Retina Robotically Aligned OCT Study
Status: NOT_YET_RECRUITING
Conditions: Retinal Disease
Interventions: DEVICE: Peripheral retina robotically aligned optical coherence tomography (OCT) system|OTHER: Likert Scales
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Boston Scientific's Cryoballoon in the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: Boston Scientific Cardiac Cryoablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Degradation of the Glycocalyx in Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage
Status: UNKNOWN
Conditions: Aneurysmal Subarachnoid Hemorrhage
Interventions: OTHER: Glycocalyx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lipiodol Localization for Ground-glass-opacity Minimal Surgery
Status: COMPLETED
Conditions: Pulmonary Lesion With Ground-glass-opacity
Interventions: PROCEDURE: Lipiodol|PROCEDURE: Hookwire|DRUG: Lipiodol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bendamustine Study in Classical Hodgkin Lymphoma Patients Over 60 Treated by Prednisone, Vinblastine and Doxorubicin
Status: COMPLETED
Conditions: Classical Hodgkin Lymphoma
Interventions: DRUG: Bendamustine|DRUG: Prednisone|DRUG: Vinblastine|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dislocated Unstable Distal Both-Bone Forearm Fractures in Children
Status: UNKNOWN
Conditions: Fracture|Forearm|Distal|Child|Treatment
Interventions: PROCEDURE: Kirschner-wire fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shock Wave Therapy On Cervical Pain Following Neck Dissection Surgery
Status: COMPLETED
Conditions: Pain|Cervical Pain
Interventions: DEVICE: extra-corporeal shock wave therapy|DRUG: topical none steroidal anti-inflammatory drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Hypoglycaemic Response Between NN1250 and Insulin Glargine in Type 1 Diabetics
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Internet-based Injury Prevention Program in Enhancing Mother's Knowledge on Child Safety
Status: COMPLETED
Conditions: Child Safety|Injury Prevention|Internet-based Intervention|Anticipatory Guidance|Chinese Mothers
Interventions: OTHER: Internet-based injury prevention program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies
Status: RECRUITING
Conditions: Ovarian Cancer|Breast Cancer|Pancreatic Cancer|Prostate Cancer|Additional Indications Below for Module 4 and 5|Non-small Cell Lung Cancer|Colorectal Cancer|Bladder Cancer|Gastric Cancer|Biliary Cancer|Cervical Cancer|Endometrial Cancer|Small Cell Lung Cancer Only in Module 5
Interventions: DRUG: AZD5305|DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: T- Dxd|DRUG: Dato-DXd|DRUG: Camizestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EU Sites: Fluid Management of Acute Decompensated Heart Failure With Reprieve Decongestion Management System (FASTR-EU)
Status: RECRUITING
Conditions: Acute Decompensated Heart Failure
Interventions: DEVICE: Reprieve Decongestion Management System|DRUG: Diuretic (furosemide, bumetanide, torsemide, hydrochlorothiazide, and/or acetazolamide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Busulfan/Clofarabine + Allogeneic Stem Cell Transplantation
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Busulfan|DRUG: Clofarabine|PROCEDURE: Allogeneic Stem Cell Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT