pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Safety and Effectiveness of Valacyclovir HCl in the Treatment of Herpes Simplex or Varicella/Zoster Infections in HIV-1 Infected Children
Status: WITHDRAWN
Conditions: Herpes Simplex|HIV Infections|Chickenpox
Interventions: DRUG: Valacyclovir hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Povidone Iodine Efficacy Study
Status: RECRUITING
Conditions: Early Childhood Caries
Interventions: DRUG: 10% povidone iodine + FV|OTHER: Placebo +FV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Clinical Trial of Unilateral or Bilateral Implantation of TecnisSymfony IOL in Cataract Patients With Presbyopia
Status: UNKNOWN
Conditions: Cataract|Presbyopia
Interventions: DEVICE: TecnisSymfony®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Upper Extremity Robot-Assisted Therapy in Stroke Patients
Status: NOT_YET_RECRUITING
Conditions: Stroke|Upper Extremity
Interventions: DEVICE: Assist-On Arm Robot Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remegal Different Doses in Patients With Refractory Partial Seizures
Status: COMPLETED
Conditions: Drug Safety|Normal Drug Tolerance|Self Efficacy
Interventions: DRUG: Remegal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Evaluation of Intracoronary Transplantation of Bone Marrow Stem Cells in Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Intracoronary Transplantation of Bone Marrow Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK and PD Study of LUM-201 in Children With Idiopathic Growth Hormone Deficiency: (OraGrowtH212)
Status: ACTIVE_NOT_RECRUITING
Conditions: Growth Hormone Deficiency
Interventions: DRUG: LUM-201
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carmustine Followed By Surgery in Treating Patients With Recurrent Supratentorial Malignant Glioma or Metastatic Brain Neoplasm
Status: UNKNOWN
Conditions: Brain and Central Nervous System Tumors|Metastatic Cancer
Interventions: DRUG: carmustine in ethanol|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Long-Term Follow-up Study
Status: ENROLLING_BY_INVITATION
Conditions: Lymphoma, Non-Hodgkin|Relapsed Non-Hodgkin Lymphoma|Refractory B-Cell Non-Hodgkin Lymphoma|Non-Hodgkin Lymphoma|Lymphoma|B Cell Lymphoma|B-Cell Non-Hodgkin's Lymphoma|Hematologic Malignancy|Relapsed/Refractory Multiple Myeloma|Relapsed/Refractory Acute Myeloid Leukemia
Interventions: BIOLOGICAL: Allogeneic CAR-T therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Retrospective/Prospective Analysis of Surgical Outcomes of Robotic Prostatectomy at The James
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: PROCEDURE: robotic radical prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Valproic Acid and Dihydroergotamine as Abortive Therapy in Pediatric Migraine
Status: TERMINATED
Conditions: Migraine in Children
Interventions: DRUG: Valproic Acid (VPA)|DRUG: Dihydroergotamine (DHE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Hawthorn Vinegar, Black Mulberry Syrup and Green Tea on Oral Mucositis
Status: COMPLETED
Conditions: Mucositis|Quality of Life
Interventions: OTHER: Hawthorn Vinegar Group|OTHER: Black Mulberry Syrup Group|OTHER: Green Tea Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility Study of Compensation for Blindness With the PRIMA System in Patients With Dry Age Related Macular Degeneration
Status: ACTIVE_NOT_RECRUITING
Conditions: Dry Age-related Macular Degeneration
Interventions: DEVICE: PRIMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Molecular-Metabolic Phase II Trial of Perifosine for Recurrent/Progressive Malignant Gliomas
Status: COMPLETED
Conditions: Malignant Gliomas|CNS|Brain Cancer|Cancer
Interventions: DRUG: Perifosine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Dopaminergic Signaling in Opioid Use Disorders
Status: RECRUITING
Conditions: Normal Physiology|Opioid Use Disorders
Interventions: DRUG: [11C]raclopride plus placebo|DRUG: [11C]raclopride plus drug|DRUG: [11C]NNC-112
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transitioning Young Patients' Health Care Trajectories
Status: ENROLLING_BY_INVITATION
Conditions: Health Care Utilization|Mental Health Impairment|Child, Only|Multi-morbidity
Interventions: OTHER: Transitioning young patients' health care trajectories
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Stimulan® for the Treatment of Diabetic Foot Osteomyelitis. The BIG D-FOOT Study
Status: NOT_YET_RECRUITING
Conditions: Diabete Mellitus|Foot Ulcer|Osteomyelitis - Foot|Surgical Procedure, Unspecified
Interventions: DEVICE: Calcium-sulphate granules with tobramicina+vancomicina
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identifying Functional and Psycho-social Complaints After Hospitalization for SARS-CoV-2 Infection( COVID 19)- REPERCOV
Status: UNKNOWN
Conditions: SARS-COV2|COVID19
Interventions: OTHER: questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Adjuvant Treatment Determined By Pathological Response To Neoadjvuant Nivolumab
Status: RECRUITING
Conditions: Melanoma Stage III|Melanoma
Interventions: DRUG: nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationships Between Ultrasound Data and the Impact of Lateral Epicondylar Pain
Status: COMPLETED
Conditions: Tennis Elbow|Epicondylitis, Lateral Humeral
Interventions: PROCEDURE: Ultrasound of the elbow 1, days 7 to 15|PROCEDURE: Ultrasound of the elbow 2, days 7 to 15|PROCEDURE: Ultrasound of the elbow 3, days 45 to 90
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Correlation Between Selected Haematological and Doppler Ultrasonic Parameters in Peripheral Arterial Diseased Patients
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Transcutaneous Electrical Nerve Stimulation(TENS) device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Erector Spinae Plane (ESP) Block and Thoracolumbar Interfascial Plane(TLIP) Block for the Management of Postoperative Pain in Spinal Surgery
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: PROCEDURE: Erector Spinae Plane (ESP) Block|PROCEDURE: Thoracolumbar interfacial plane (TLIP) Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Diclofenac Potassium and Rimegepant for the Acute Treatment of Migraine
Status: RECRUITING
Conditions: Migraine With Aura|Migraine Without Aura
Interventions: DRUG: Diclofenac Potassium 50Mg/Pkt Oral Pwdr|DRUG: Rimegepant 75 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stanford Tobacco Treatment Services - Virtual Reality Treatment for Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation|MindCotine Virtual Reality Mindful Exposure Therapy
Interventions: BEHAVIORAL: MindCotine's VR app
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Ibrutinib in Combination With Rituximab in Previously Untreated Subjects With Follicular Lymphoma
Status: COMPLETED
Conditions: Follicular Lymphoma|B-cell Lymphoma|Non-Hodgkin's Lymphoma
Interventions: DRUG: Ibrutinib|DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: POPQ Versus Simulated Apical Support as a Guideline for Anterior or Posterior Repair During Vaginal Reconstruction
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: anterior or posterior colporrhaphy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surufatinib in Recurrent/Metastatic Head and Neck Adenocarcinomas
Status: UNKNOWN
Conditions: Head and Neck Cancers - Salivary Gland
Interventions: DRUG: Surufatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HAIC Plus Lenvatinib and PD-1 Antibody Versus HAIC Plus Lenvatinib for Advanced HCC
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Hepatic arterial infusion chemotherapy|DRUG: Folfox Protocol|DRUG: Lenvatinib|DRUG: PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Site Evaluation of the Pain Relief, Support, Fit and Comfort From Use of a Custom Knee or Ankle Brace in Persons Suffering From Chronic Ankle or Knee Pain and Instability
Status: COMPLETED
Conditions: Joint Instability
Interventions: DEVICE: Dr. Scholl's Prototype Ankle Brace|DEVICE: Dr. Scholl's Prototype Knee Brace
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Early Debriefing and Enhanced Educative Components on Direct Oral Anticoagulant Adherence After Venous Thromboembolism.
Status: UNKNOWN
Conditions: Venous Thromboembolism
Interventions: OTHER: Debriefing and educative components|OTHER: Without debriefing and educative components
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Different Surgical Procedures of Peroral Endoscopic Myotomy(POEM) for Esophageal Achalasia
Status: UNKNOWN
Conditions: Esophageal Achalasia|Esophageal Motility Disorders
Interventions: PROCEDURE: short-myotomy|PROCEDURE: long-myotomy|PROCEDURE: full-thickness myotomy|PROCEDURE: circular myotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2 Study of HYP-2090PTSA in Patients With Advanced Solid Tumors Harboring KRAS Mutation
Status: RECRUITING
Conditions: Safety|Tolerability|Efficacy
Interventions: DRUG: Test product: HYP-2090PTSA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic ACL Surgery
Status: COMPLETED
Conditions: ACL Injury|Postoperative Pain
Interventions: DRUG: Ketorolac|DRUG: Oxycodone-Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lipid-lowering Agents in Patients With Dermatomyositis and Polymyositis
Status: TERMINATED
Conditions: Treatment Side Effects
Interventions: DRUG: Lipid-lowering agents (Artovastatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture Versus Placebo Acupuncture During In Vitro Fertilization (IVF) Embryo Transfer
Status: COMPLETED
Conditions: Infertility
Interventions: DEVICE: Acupuncture (Carbo®)|DEVICE: Placebo acupuncture (Strietberger®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Functional Snack Foods With Safflower Oil and Soy in Postmenopausal Women Having Metabolic Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Metabolic Syndrome|Overweight
Interventions: OTHER: wheat-safflower oil pretzels|OTHER: soy-safflower oil pretzels|OTHER: control wheat pretzels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating AMG 193 in Combination With Other Therapies in Participants With Advanced Gastrointestinal, Biliary Tract, or Pancreatic Cancers With Homozygous Methylthioadenosine Phosphorylase (MTAP)-Deletion
Status: RECRUITING
Conditions: Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers
Interventions: DRUG: AMG 193|DRUG: Gemcitabine|DRUG: Nab-paclitaxel|DRUG: Modified FOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Lot-to-lot Consistency (3 Lots of GSK Biologicals' 10-valent Pneumococcal Conjugate Vaccine) & Non-inferiority Study
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Pneumococcal (vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Clinical Efficacy of Acupuncture on the Liver Meridian in Men With Erectile Dysfunction Reserve
Status: RECRUITING
Conditions: Erectile Dysfunction|Acupuncture Therapy|Median Nerve Disease
Interventions: OTHER: electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Tibial Nerve Selective Neurotomy Compared to Botulinum Toxin Injections for Spastic Foot Treatment in Post-stroke Patients According to a Goal-centered Approach
Status: RECRUITING
Conditions: Post Stroke Seizure|Spastic Foot
Interventions: PROCEDURE: Tibial nerve selective neurotomy|DRUG: Botulinum toxin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Tailored Bowel Preparation Strategy Guided by a Predictive Model
Status: COMPLETED
Conditions: Bowel Cleansing Quality|Colonoscopy
Interventions: DRUG: Polyethylene Glycol (PEG)|DRUG: Polyethylene Glycol (PEG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Difference in Patellar Tracking Before and After Journey II BCS Total Knee Arthroplasty, Evaluated With 4D CT Imaging
Status: TERMINATED
Conditions: Knee|Replacement|Arthroplasty
Interventions: DEVICE: onlay patella button|PROCEDURE: Conventional procedure; NO onlay patella button
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial in Patients on Long-term Colchicine With Colchicine-resistant Familial Mediterranean Fever (FMF) to Evaluate the Efficacy of On-demand Anakinra Treatment for Painful Attacks in Patients Who Refuse Continuous Daily Therapy
Status: NOT_YET_RECRUITING
Conditions: FMF
Interventions: DRUG: ANAKINRA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aronia and Cognitive Fitness
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain Vascular Function|Cognition
Interventions: DIETARY_SUPPLEMENT: Aronia|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pioglitazone Therapy of Autoimmune Pulmonary Alveolar Proteinosis Autoimmune Pulmonary Alveolar Proteinosis
Status: COMPLETED
Conditions: Autoimmune Pulmonary Alveolar Proteinosis
Interventions: DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Intraosseous Anaesthesia Using a Computerized System (QuickSleeper) to Conventional Anesthesia
Status: COMPLETED
Conditions: Deep Caries|Molar Incisor Hypomineralisation
Interventions: PROCEDURE: intraosseous anaesthesia using a computerized system|PROCEDURE: conventional anasthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hydroxy-urea and Temozolomide in Patients With a Recurrent Malignant Brain Tumor (Glioblastoma)
Status: UNKNOWN
Conditions: Glioma|Glioblastoma
Interventions: DRUG: Hydroxyurea|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Motorized Cryotherapy on Early Effusion, Swelling, and Pain After Anterior Cruciate Ligament Reconstruction
Status: COMPLETED
Conditions: Cryotherapy Effect
Interventions: DEVICE: Motorized cryotherapy|DEVICE: Classical cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Butorphanol on Colonoscopy for Patients With Postoperative Visceral Pain
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: Butorphanol Injection|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Melatonin and Metformin on Glycemic Control Genotoxicity and Cytotoxicity Markers in Patients With Prediabetes
Status: UNKNOWN
Conditions: PreDiabetes
Interventions: DRUG: melatonin|DRUG: metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic Assisted Sacral Colpopexy : A Prospective Study Assessing Outcomes With Learning Curves
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Device- Robotic sacral colpopexy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Instrument-Assisted Soft Tissue Mobilization Versus High Power Pain Threshold Ultrasound For Trapezius Myofascial Trigger Points
Status: COMPLETED
Conditions: Myofascial Pain Syndrome of Neck
Interventions: DEVICE: Instrument assisted soft tissue mobilization ( IASTM ) and Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of DERMABOND ProPen in Closure of Colectomy Wounds
Status: TERMINATED
Conditions: Wound
Interventions: PROCEDURE: Dermabond ProPen (2-octylcyanoacrylate)|PROCEDURE: Skin closure with skin staples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thoracoscopic Lobectomy Using Nonintubated Anesthesia Versus Intubated General Anesthesia for Lung Cancer Patients
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: PROCEDURE: thoracoscopic lobectomy and mediastinal lymph node dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relevance of an Adapted and Supervised Physical Activity Program in Fibromyalgia Patients. The FIMOUV 1 Study.
Status: COMPLETED
Conditions: Fibromyalgia|Physical Activity
Interventions: OTHER: physical activity program|OTHER: Advice and recommendations of physical activity at home
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Nivolumab in Combination With 177Lu-girentuximab for Kidney Cancer
Status: RECRUITING
Conditions: Clear Cell Renal Cell Carcinoma|Kidney Cancer|Advanced Renal Cell Carcinoma
Interventions: DRUG: 177Lu-labeled-girentuximab|DRUG: Nivolumab|DIAGNOSTIC_TEST: 89Zr-girentuximab PET/CT|DIAGNOSTIC_TEST: 177Lu whole body (WB) planar and SPECT/CT scans
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Investigate the Safety and Tolerability of EP395 in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|COPD
Interventions: DRUG: EP395|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Preoperative Radiation for Head and Neck Cancers (HyPR-HN)
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: RADIATION: 46 Gy Radiation Therapy|RADIATION: 40 Gy Radiation Therapy|RADIATION: 35 Gy Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hormone Therapy With or Without Surgery or Radiation Therapy in Treating Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: bicalutamide|DRUG: buserelin|DRUG: flutamide|DRUG: goserelin|DRUG: leuprolide acetate|DRUG: nilutamide|PROCEDURE: orchiectomy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Homoharringtonine Compared With Hydroxyurea for Chronic Myelogenous Leukemia That Has Not Responded to Interferon Alfa
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: hydroxyurea|DRUG: Homoharringtonine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal SB-705498 in Healthy Volunteers
Status: COMPLETED
Conditions: Rhinitis
Interventions: DRUG: SB-705498|DRUG: SB-705498|DRUG: SB-705498|DRUG: SB-705498|DRUG: SB-705498|DRUG: Placebo|DRUG: SB-705498|DRUG: SB-705498|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Individualized Oxygen Dynamic on Prognosis of Patients With High-risk Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Disease|High Risk Sex
Interventions: PROCEDURE: mean artery pressure|PROCEDURE: bispectral index|PROCEDURE: Brain oxygen saturation|OTHER: Controlled
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Union Rate of Transverse Tibia Fracture
Status: TERMINATED
Conditions: Closed Transverse Fracture of Shaft of Tibia
Interventions: DEVICE: Conventional Compression|DEVICE: Standard Backslapping|DEVICE: Dynamic Locking with Backslapping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hypovitaminosis D and Vitamin D Supplementation on Fracture Nonunion Rates
Status: COMPLETED
Conditions: Hypovitaminosis D
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Salsalate Therapy to Reduce Insulin Resistance and Cardiovascular Risk
Status: COMPLETED
Conditions: Atherosclerosis|Cardiovascular Disease|Inflammation|Insulin Resistance|Noninsulin-dependent Diabetes Mellitus
Interventions: DRUG: Salsalate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Addition of UT-15C SR to Pulmonary Arterial Hypertension Patients Currently Receiving Tyvaso®
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: UT-15C SR|DRUG: Tyvaso Inhalation Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluoride Varnish For Childsmile Nursery School Attenders
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: Duraphat® Fluoride Varnish|BEHAVIORAL: treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Function "Stop Before Hypoglycemia" on External Insulin Pump
Status: TERMINATED
Conditions: Type I Diabetes
Interventions: DEVICE: MiniMed™ 640G|DEVICE: Captor CGM Enlite®|DEVICE: SmartGuard®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety, Tolerability, Biodistribution and Anti Tumour Activity of 177LU-OPS201 With Companion Imaging 68Ga-OPS202 PET/CT in Previously Treated Subjects With Locally Advanced or Metastatic Cancers Expressing Somatostatin Receptor 2 (SSTR2)
Status: TERMINATED
Conditions: Small Cell Lung Cancer and Breast Cancer
Interventions: DRUG: Satoreotide tetraxetan|DRUG: Satoreotide trizoxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Drug Interaction Between MYK-224 and Itraconazole and Verapamil in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: MYK-224|DRUG: Itraconazole|DRUG: Verapamil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of EPI-743 in Children With Leigh Syndrome
Status: COMPLETED
Conditions: Leigh Syndrome
Interventions: DRUG: Placebo|DRUG: EPI-743 15 mg/kg|DRUG: EPI-743 5 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel-coated or Uncoated AngioSculpt Scoring Balloon Catheter
Status: COMPLETED
Conditions: In-stent Arterial Restenosis
Interventions: DEVICE: uncoated AngioSculpt(R)|COMBINATION_PRODUCT: Drug coated AngioSculpt(R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
Status: RECRUITING
Conditions: Atrial Fibrillation|Coronary Heart Disease|Cardiovascular Diseases|Heart Failure|Hypertension|Peripheral Arterial Disease|Stroke, Ischemic|Asthma|Chronic Obstructive Pulmonary Disease|Obesity|Cancer|Chronic Kidney Diseases|Diabetes Mellitus|Dementia|Depression|Epilepsy|Mental Health Disorder|Rheumatoid Arthritis|Blood Pressure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Olaparib +/- Cediranib or Chemotherapy in Patients With Platinum-resistant Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Olaparib|DRUG: Cediranib|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Conor Sirolimus-eluting Coronary Stent to the Taxus Liberte Paclitaxel-eluting Coronary Stent in the Treatment of Coronary Artery Lesions
Status: TERMINATED
Conditions: Coronary Atherosclerosis
Interventions: DEVICE: NEVO™ Sirolimus-eluting Coronary Stent System|DEVICE: Drug-eluting stent (TAXUS Liberte Paclitaxel-eluting Coronary Stent System)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Acceptability and Safety Study of the Transfer From Subutex to Suboxone in Opioid- Dependent Subjects (Study P04843)(COMPLETED)
Status: COMPLETED
Conditions: Opiate Dependence|Drug Dependence
Interventions: DRUG: Suboxone, Buprenorphine Hydrochloride + Naloxone, SCH 484|DRUG: Subutex, Buprenorphine Hydrochloride, SCH 28444
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block as a Rescue Pain Therapy in Patients Undergoing Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Regional Anesthesia Morbidity|Cholecystitis, Chronic
Interventions: PROCEDURE: Erector Spina Plane Group|PROCEDURE: IV analgesic intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Endothelial Function in Obese Adolescents
Status: COMPLETED
Conditions: Insulin Resistance|Glucose Intolerance|Obesity|Atherosclerosis
Interventions: OTHER: Reactive hyperemia peripheral artery tonometry (Rh-PAT)|OTHER: Blood levels for glucose, insulin, lipids and adipocytokines
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Designed to Compare the Tolerability of an Increased Dose of Enteric-coated Mycophenolate Acid (MPA) in Renal Transplant Patients Whose Dose of Mycophenolate Mofetil (MMF) Was Reduced Due to Gastrointestinal Symptoms
Status: TERMINATED
Conditions: Renal Transplantation
Interventions: DRUG: Enteric-coated Mycophenolate Acid (EC-MPA)|DRUG: Mycophenolate Mofetil (MMF)|DRUG: Placebo MMF|DRUG: Placebo EC-MPA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 4 mm Implants in Fixed Cross-Arch Prostheses
Status: ACTIVE_NOT_RECRUITING
Conditions: Jaw Edentulous
Interventions: DEVICE: Roxolid short implant, 4 mm length (4)|DEVICE: Roxolid short implant, 4 mm length (2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: HYPIC Hypnosis for Procedural Pain in the Intensive Care Unit
Status: COMPLETED
Conditions: Invasive Procedure
Interventions: OTHER: Hypnosis|OTHER: No hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Pharmacokinetic Study of Intranasal 2-DG in Healthy Volunteers
Status: COMPLETED
Conditions: Acute Nasopharyngitis
Interventions: DRUG: 2-Deoxyglucose|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The CATCH Prostate Cancer Trial: Cabazitaxel And Tasquinimod in Men With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: tasquinimod|DRUG: tasquinimod 0.25 mg; 0.5 mg|DRUG: tasquinimod 0.25 mg; 0.5 mg; 1.0 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imatinib Mesylate, Vatalanib, and Hydroxyurea in Treating Patients With Recurrent or Relapsed Malignant Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: hydroxyurea|DRUG: imatinib mesylate|DRUG: vatalanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resveratrol-Based Gel Application in a Palatal Wound Following Free Gingival Graft Surgery
Status: RECRUITING
Conditions: Mucogingival Defects
Interventions: DRUG: Resveratrol-Based gel|DRUG: Hyaluronic acid gel 0.2%|DEVICE: Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Chemoradiation Therapy and Epitope Peptide Vaccine Therapy in Treating Patients With Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: BIOLOGICAL: URLC10, TTK, KOC1, VEGFR1, VEGFR2, cisplatin, fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Investigate the Safety, Tolerability, Pharmacokinetics and the Relative Bioavailability of BI 1026706
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1026706 Placebo|DRUG: BI 1026706
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Oral vs. Non-oral Contraceptives on the GH/IGF-1 Axis
Status: COMPLETED
Conditions: Bone; Disorder, Development and Growth
Interventions: DRUG: Combined Oral Contraceptive|DRUG: Transdermal Contraceptive|DRUG: Contraceptive Vaginal Ring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: [18F]MK-3328 as a Possible Novel Positron Emission Tomography (PET) Tracer for the Detection of Brain Amyloid Plaques (MK-3328-002)
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: [18F]MK-3328
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Azithromycin Plus Chloroquine Versus Artemether-Lumefantrine For The Treatment Of Uncomplicated P. Falciparum Malaria In Children In Africa
Status: COMPLETED
Conditions: Malaria, Falciparum
Interventions: DRUG: Azithromycin plus Chloroquine|DRUG: Artemether-lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vegan Diets: the Short-term Effects on Daily Muscle Protein Synthesis Rates as Compared to Omnivorous Diets in Older Adults Assessed by D2O.
Status: COMPLETED
Conditions: Sarcopenia
Interventions: OTHER: Vegan diet (intervention)|OTHER: Omnivorous diet (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Efficacy and Safety of Two Dosing Regimens of Olokizumab (OKZ), Compared to Placebo, in Subjects With Rheumatoid Arthritis (RA) Who Were Taking an Existing Medication Called a Tumour Necrosis Factor Alpha Inhibitor But Had Active Disease
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Olokizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cangrelor Neonatal PK/PD and Safety Study
Status: COMPLETED
Conditions: Partial Obstruction of Systemic to Pulmonary Artery Shunt|Complete Obstruction of Systemic to Pulmonary Artery Shunt
Interventions: DRUG: Cangrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: MRI (Including Spectroscopy and Fat-Saturations and Diffusion-Weighted Imaging) in Cervical Cancer
Status: COMPLETED
Conditions: Uterine Cervical Neoplasms
Interventions: DEVICE: MR Spectroscopy|DEVICE: Fat-Saturation and Diffusion-Weighted Imaging|DEVICE: Dynamic Contrast Enhancement MRI (MR-DCE)|DEVICE: Diffusion Tensor Imaging (DTI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Study of Safety and Functional Imaging of cG250 and Sunitinib in Patients With Advanced Renal Cell Carcinoma
Status: TERMINATED
Conditions: Renal Cell Carcinoma (RCC)
Interventions: BIOLOGICAL: Chimeric monoclonal antibody cG250|DRUG: Sunitinib malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Aliskiren on Patient With Heart Failure and a Normal Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: aliskiren|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial on The Efficacy of Hypertonic Saline on Non-CF CSLD.
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: DRUG: Nebulized 5% Hypertonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Disitamab Vedotin Combined With Sintilimab as First-line Treatment of Elderly Patients With Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Disitamab Vedotin Combined With Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: B. Infantis Supplementation to Improve Immunity in Infants Exposed to HIV
Status: RECRUITING
Conditions: Hiv|Vaccine Reaction|Microbial Colonization|Infant Development
Interventions: DIETARY_SUPPLEMENT: B. infantis Rosell®-33|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Somatosensory Processing in Focal Hand Dystonia
Status: UNKNOWN
Conditions: Focal Hand Dystonia|Musician's Dystonia|Writer's Cramp|Dystonic Cramp
Interventions: OTHER: Tactile training + sham rTMS|OTHER: Tactile training + rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acceptance and Commitment Therapy and Test Anxiety
Status: RECRUITING
Conditions: Therapy, Directly Observed
Interventions: BEHAVIORAL: ACCEPTANCE AND COMMITMENT THERAPY-BASED PSYCOEDUCATION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Tirzepatide|DRUG: Dulaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Desirudin With Heparin to Prevent Vein Clots After Heart and Lung Surgery
Status: COMPLETED
Conditions: Deep Venous Thrombosis
Interventions: DRUG: Desirudin (Iprivask™)|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of an Autologous Tumor Infiltrating Lymphocyte (TIL) Therapy in Patients With Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor
Interventions: BIOLOGICAL: BEN101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Analgesia With Interfascial Continuous Wound Infiltration: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: 19Gx500-mm Pajunk InfiltraLong® catheter|DRUG: morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Dose Study to Assess the Pharmacokinetics, Safety, and Tolerability of Orally Administered SYN 020
Status: COMPLETED
Conditions: Enteritis Caused by Radiation
Interventions: DRUG: SYN-020 Delayed Release Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: FMT for Post-acute COVID-19 Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Post-Acute COVID19 Syndrome|COVID-19
Interventions: PROCEDURE: Faecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Rituximab Combined With Cyclosporine in the Treatment of Idiopathic Membranous Nephropathy
Status: RECRUITING
Conditions: Idiopathic Membranous Nephropathy
Interventions: DRUG: Rituximab|DRUG: Modified Ponticelli regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Barriers to Use of Remote Monitoring in Patients With Implantable Cardioverter Defibrillators
Status: COMPLETED
Conditions: Cardiac Patients|Implantable Cardioverter Defibrillator
Interventions: BEHAVIORAL: Teaching Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Lovaza in Adolescents With Mild to Moderately Elevated Triglycerides
Status: TERMINATED
Conditions: Hypertriglyceridemia
Interventions: DRUG: Lovaza|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparability Study of the Phase 3 Lot and a Single Commercial Lot of NicVAX in Healthy Adult Smokers
Status: COMPLETED
Conditions: Smoking
Interventions: BIOLOGICAL: NicVAX Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy, Safety and Tolerability of Crisaborole and PF-07038124 With and Without NBUVB in Vitiligo
Status: COMPLETED
Conditions: Vitiligo
Interventions: DRUG: Crisaborole 2 % Topical Ointment|DRUG: PF-07038124 0.01% topical ointment|DEVICE: NBUVB phototherapy|DEVICE: Sham phototherapy|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring the Synergistic Effects of Virtual Reality and Retrogressive Imagery on Basketball Free Throw Performance and Self-efficacy Among University Students: A Randomized Controlled Trial
Status: COMPLETED
Conditions: RETI|VR|FTSE
Interventions: BEHAVIORAL: Retrogressive imagery (RETI)|BEHAVIORAL: Virtual Reality (VR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Safety and Tolerability Study of ABT-089 in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention-Deficit/Hyperactivity Disorder
Interventions: DRUG: ABT-089
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel, Cisplatin, Irinotecan and Bevacizumab (TPCA) in Metastatic Esophageal and Gastric Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Stomach Cancer
Interventions: DRUG: Bevacizumab|DRUG: Docetaxel|DRUG: Cisplatin|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AntiCMV molécules Monitoring in Real-life in Stem Cell Recipients
Status: RECRUITING
Conditions: Hematopoietic Stem Cell Transplantation|Cytomegalovirus Infections|Antivirals|Antiviral Drug Resistance
Interventions: OTHER: Real-life observatory of efficacy and resistance to anti CMV molecules in stem cell recipients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-release Tablets Versus Desvenlafaxine Succinate Sustained-release Tablets Targeting Anhedonia in Patients With Major Depression Disorder
Status: RECRUITING
Conditions: Anhedonia
Interventions: DRUG: Toludesvenlafaxine hydrochloride sustained-release tablets|DRUG: Desvenlafaxine succinate sustained-release tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neo-adjuvant Evaluation of Glioma Lysate Vaccines in WHO Grade II Glioma
Status: ACTIVE_NOT_RECRUITING
Conditions: Oligodendroglioma|Astrocytoma, Grade II|Glioma, Astrocytic|Glioma|Malignant Glioma|Oligoastrocytoma, Mixed
Interventions: BIOLOGICAL: GBM6-AD and poly-ICLC before and after surgery|BIOLOGICAL: GBM6-AD and poly-ICLC after surgery only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT