pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Preventing Cognitive Decline With Metformin
Status: RECRUITING
Conditions: Cognitive Decline
Interventions: DRUG: Metformin XR, 500-2000mg nocte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A-dmDT390-bisFv(UCHT1) Fusion Protein With Ionizing Radiation and Pembrolizumab for the Treatment of Stage IV Melanoma
Status: UNKNOWN
Conditions: Stage IV Melanoma
Interventions: BIOLOGICAL: A-dmDT390-bisFv(UCHT1)|BIOLOGICAL: Pembrolizumab|RADIATION: Ionizing Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Study of CJ-40001 and NESP® After Single Dose Administration in Health Male Volunteers
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: CJ-40001 60ug|DRUG: NESP 60ug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Glossopharyngeal Nerve Block on Post Tonsillectomy Pain Among Egyptian Children
Status: COMPLETED
Conditions: Post Tonsillectomy Pain
Interventions: DRUG: Bupivacaine Hydrochloride 0.5% Injection Solution|DRUG: Saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of YHD1119 in Patients With Peripheral Neuropathic Pain
Status: COMPLETED
Conditions: Peripheral Neuropathic Pain
Interventions: DRUG: YHD1119|DRUG: Lyrica
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Is IFN-beta Treatment in MS Useful After a Washout Period in Patients With Neutralizing Antibodies to Interferon Beta
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: Interferon-beta-1a|DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ifosfamide, Teniposide, and Paclitaxel in Treating Patients With Relapsed Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: ifosfamide|DRUG: paclitaxel|DRUG: teniposide|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Transhepatic Versus Subcostal Views to Assess Inferior Vena Cava Variation in Pediatric Patients
Status: NOT_YET_RECRUITING
Conditions: Inferior Vena Cava Abnormality
Interventions: DIAGNOSTIC_TEST: Ultrasound Analysis of Inferior Vena Cavae (IVC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Identification of Genetic and Cellular Markers Associated With Vascular Endothelial Modifications in Cutaneous Arteriovenous Malformations
Status: UNKNOWN
Conditions: Cutaneous Arteriovenous Malformations
Interventions: GENETIC: blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Postpartum Weight Loss and Exercise (PRIDE)
Status: COMPLETED
Conditions: Gestational Diabetes|Glucose Intolerance
Interventions: BEHAVIORAL: Non-intervention group|BEHAVIORAL: Face to face|BEHAVIORAL: Telehelath Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: HIIT Versus MICT on Abdominal Fat Mass and Lipid Oxidation in Postmenopausal Women (MATISSE)
Status: COMPLETED
Conditions: Overweight|Post Menopausal Women
Interventions: OTHER: Training programs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Mirror Therapy With Sensory Motor Training in Children With CP
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: Experimental: Mirror therapy with sensory motor training.|OTHER: Experimental: Mirror Therapy with motor training|OTHER: Experimental: Motor Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Metoprolol Succinate Prolonged-Release Tablet in Patients With Mild to Moderate Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: metoprolol succinate prolonged-release tablet and felodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3090106 in Participants With Sjögren's Syndrome (SS)
Status: COMPLETED
Conditions: Sjögren's Syndrome
Interventions: DRUG: LY3090106|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pentoxifylline and Combination Antiretroviral Therapy to Improve Blood Vessel Function in HIV-Infected People
Status: COMPLETED
Conditions: HIV|Vascular Diseases|Cardiovascular Diseases|Atherosclerosis|HIV Infections
Interventions: DRUG: Combination antiretroviral therapy (cART)|DRUG: Pentoxifylline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New Anastomotic Device for End to End Vascular Anastomosis in the Treatment of Peripheral Vascular Disease
Status: UNKNOWN
Conditions: Peripheral Vascular Disease|Femoral Occlusive Disease|Femoropopliteal Occlusive Disease|Aortoiliac Atherosclerosis
Interventions: DEVICE: mechanical anastomosis without suture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Gut Microbiome as an Indicator of Readiness for Head & Neck Cancer Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer of Head and Neck|Nutrition Aspect of Cancer
Interventions: DIETARY_SUPPLEMENT: Nestlé Impact Advanced Recovery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VNP20009 in Treating Patients With Advanced or Metastatic Solid Tumors That Have Not Responded to Previous Therapy
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: salmonella VNP20009|DRUG: cefixime|DRUG: ceftriaxone sodium|DRUG: ciprofloxacin|DRUG: trimethoprim-sulfamethoxazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Cell Immunity Response to Vaccination Against Influenza in Patients With Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Agrippal S1 (Influenza vaccination)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD), and Therapeutic Activity of Selicrelumab (RO7009789) With Vanucizumab or Bevacizumab in Participants With Metastatic Solid Tumors
Status: COMPLETED
Conditions: Advanced/Metastatic Solid Tumors
Interventions: DRUG: Selicrelumab|DRUG: Vanucizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Localisation of Potential Insulin Deposits in Normal Weight and Obese Diabetics Using 6 mm and 12 mm Long Needles
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Delivery Systems
Interventions: DEVICE: NovoFine® needle 6 mm|DEVICE: NovoFine® needle 12 mm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of De_Intensified Postoperative Radiation Therapy for HPV Associated Oropharyngeal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Locally Injected Bradykinin Antagonist for TReatment of OSteoarthritiS
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: MEN16132 - 0.125 mg|DRUG: MEN16132 - 0.25 mg|DRUG: MEN16132 - 0.5 mg|DRUG: MEN16132 - 0.5 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Conservative Treatment of Functional Defecatory Disorders in Females With Pelvic Organ Prolapse
Status: RECRUITING
Conditions: Pelvic Floor Prolapse|Functional Constipation|Rectocele
Interventions: PROCEDURE: Biofeedback therapy|PROCEDURE: Tibial neuromodulation|BEHAVIORAL: Pelvic floor muscles training|BEHAVIORAL: Diet modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FS-67 in the Treatment of Pediatric Patients With Ankle Sprain
Status: COMPLETED
Conditions: Ankle Sprain
Interventions: DRUG: FS-67 Patch|OTHER: Placebo Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effects of Oxytocin in Adults With Obesity and Binge-eating Disorder
Status: RECRUITING
Conditions: Binge-eating Disorder
Interventions: DRUG: TNX-1900 (Tonix Pharmaceuticals)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of the Uriprene Stent Following Uncomplicated Ureteroscopy
Status: COMPLETED
Conditions: Unilateral Ureteral Stone|Renal Stone Fragments ≤ 2mm
Interventions: DEVICE: Post-Ureteroscopy ADVA-Tec Uriprene™ Degradable Temporary Ureteral Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parent Engagement Package: Comparing Strategies for Engaging Parents Into Parenting Programs
Status: COMPLETED
Conditions: Patient Compliance
Interventions: OTHER: Enrollment Flyer|OTHER: Testimonial Booklet|OTHER: Teacher Endorsement|OTHER: Provider Engagement Call
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Hypotensive Anesthesia on the Perfusion Index
Status: COMPLETED
Conditions: Controlled Hypotension for Nasal Surgeries
Interventions: COMBINATION_PRODUCT: Massimo device|DRUG: Nitroglycerin drug|DRUG: Labetalol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of NaviFUS System add-on Bevacizumab (BEV) in Recurrent GBM Patients
Status: COMPLETED
Conditions: Glioblastoma Multiforme|Glioblastoma|Glioma|Brain Tumor|Neoplasms|Neoplasms, Nerve Tissue
Interventions: DEVICE: NaviFUS System|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Trial of Decitabine (Dacogen) Administered as a 3-hour Infusion to Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Decitabine (Dacogen)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Bleaching Technique: Efficacy and Tooth Sensitivity
Status: COMPLETED
Conditions: Tooth Bleaching|Tooth Sensitivity
Interventions: PROCEDURE: Combined Bleaching(2x20)|PROCEDURE: Combined Bleaching(2x20) with arginine|PROCEDURE: Combined Bleaching (1x20)|PROCEDURE: Combined Bleaching(1x20) with arginine|DRUG: 8% arginine and calcium carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Monitoring and Management of Vaginal Health Via Multifunctional OCT/OCTA/OCE Endoscopy
Status: RECRUITING
Conditions: Genitourinary Syndrome of Menopause
Interventions: DEVICE: CO2 laser|DEVICE: OCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized Trial of DHA for Retinitis Pigmentosa Patients Receiving Vitamin A
Status: COMPLETED
Conditions: Retinitis Pigmentosa
Interventions: DIETARY_SUPPLEMENT: Vitamin A|DIETARY_SUPPLEMENT: Docosahexaenoic acid|DIETARY_SUPPLEMENT: Control fatty acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Immunonutrition on Nutritional Status in Colorectal Cancer Patients
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DIETARY_SUPPLEMENT: Preoperative Immunonutrition|DIETARY_SUPPLEMENT: Perioperative Immunonutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Indirect Calorimetry Guided Energy Provision in Critically Ill Patients With Obesity
Status: RECRUITING
Conditions: Critical Illness|Obesity
Interventions: OTHER: Indirect calorimetry|OTHER: Indirect calorimetry (Standard care nutrition arm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Letrozole in Preventing Breast Cancer in Postmenopausal Women Who Are at Increased Risk for Breast Cancer Due to High Breast Density
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: letrozole|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Enhanced Recovery at Cesarean Birth to Improve Postoperative Outcomes and Reduce Postoperative Length of Stay
Status: COMPLETED
Conditions: Cesarean Section
Interventions: DRUG: ketorolac|OTHER: Chewing Gum|PROCEDURE: Enhanced Recovery Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ingestion of Lipids and Changes in Cerebral Blood Flow of People With Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: 60 grams of fat plus water solution|OTHER: Pure water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ertapenem Sodium (MK-0826) Versus Piperacillin/Tazobactam Sodium for the Treatment of Diabetic Foot Infections in Chinese Adults (MK-0826-061)
Status: COMPLETED
Conditions: Infection; Diabetic Foot
Interventions: DRUG: Ertapenem sodium|DRUG: Piperacillin/tazobactam sodium|DRUG: Piperacillin/tazobactam-matching placebo|DRUG: Amoxicillin/clavulunate potassium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Danggui-Sayuk-Ga-Osuyu-Saenggang-tang on Korean Patients With Cold Hypersensitivity in the Hands
Status: COMPLETED
Conditions: Cold Hypersensitivity
Interventions: DRUG: Danggui-Sayuk-Ga-Osuyu-Saenggang-tang|DRUG: Placebo: corn starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SpO2 Accuracy of Noninvasive Pulse Oximeter Sensor With Motion Conditions
Status: COMPLETED
Conditions: Healthy|Hypoxia
Interventions: DEVICE: Experimental Masimo RD SET SpO2 Adhesive Sensors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Serratus Plane Block With Parenteral Opioid Analgesia Versus Patient Controlled Analgesia in Rib Fractures
Status: UNKNOWN
Conditions: Thoracic Injuries|Rib Fractures|Anaesthesia, Local|Levobupivacaine|Analgesia, Patient-Controlled|Pain
Interventions: PROCEDURE: Serratus plane block|OTHER: Patient controlled analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Automated Insulin Delivery for INpatients With DysGlycemia (AIDING) Feasibility
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DEVICE: The Omnipod 5/Horizon HCL system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Tetravalent Meningococcal Diphtheria Toxoid Conjugate Vaccine in Toddlers 9 to 18 Months of Age
Status: COMPLETED
Conditions: Meningitis|Meningococcal Infection
Interventions: BIOLOGICAL: Meningococcal Polysaccharide Diphtheria Protein Conjugate (Menactra®)|BIOLOGICAL: Meningococcal Polysaccharide Diphtheria Protein Conjugate (Menactra®)|BIOLOGICAL: Meningococcal Polysaccharide Diphtheria Protein Conjugate (Menactra®)|BIOLOGICAL: Meningococcal Polysaccharide Diphtheria Protein Conjugate (Menactra®)|BIOLOGICAL: Meningococcal Polysaccharide Diphtheria Protein Conjugate (Menactra®)|BIOLOGICAL: A/C/Y/W-135, Meningococcal Polysaccharide Vaccine (Menomune®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Estrogen Dosing in Turner Syndrome: Pharmacology and Metabolism
Status: COMPLETED
Conditions: Turner Syndrome|Hypogonadism|Premature Ovarian Failure
Interventions: DRUG: 17 B estradiol orally|DRUG: 17 B estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine and Postoperative Cognitive Dysfunction
Status: COMPLETED
Conditions: Post Operative Cognitive Dysfunction
Interventions: DRUG: Ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Renal Effects of Hormones/Biomarkers in Transgender PrEP Recipients
Status: COMPLETED
Conditions: Transgender|Renal Function|Hormone Replacement Therapy
Interventions: DIAGNOSTIC_TEST: IHX-CL measurements|DRUG: Iohexol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study on the Safety and Effectiveness of Switching Between Two Forms of Tapentadol in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: tapentadol (CG5503) Immediate Release IR|DRUG: tapentadol (CG5503) Extended Release (ER)|DRUG: tapentadol (CG5503) Immediate Release (IR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Corneal Epithelium Repair and Therapy Using Autologous Limbal Stem Cell Transplantation
Status: UNKNOWN
Conditions: Corneal Disease|Pterygium|Myopia|Hyperopia
Interventions: PROCEDURE: LSCs and amniotic membrane (Modified Technique)|PROCEDURE: Amniotic membrane only (Traditional Technique)|PROCEDURE: PRK, LSCs, and amniotic membrane (Modified Technique)|PROCEDURE: PRK only (Traditional Technique)|DRUG: Levofloxacin|DRUG: Betamethasone|DRUG: Limbal stem cells (LSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EDEMA2: Evaluation of DX-88's Effect in Mitigating Angioedema
Status: COMPLETED
Conditions: Hereditary Angioedema (HAE)
Interventions: DRUG: DX-88 (ecallantide)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Disulfiram Plus Arsenic Trioxide In Patients With Metastatic Melanoma and at Least One Prior Systemic Therapy
Status: TERMINATED
Conditions: Metastatic Melanoma
Interventions: DRUG: Disulfiram|DRUG: Arsenic trioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carfilzomib/Cyclophosphamide/Dexamethasone With Maintenance Carfilzomib in Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: PROCEDURE: Autologous Stem Cell Transplant (ASCT)|DRUG: Consolidation with 4 cycles of CarCyDex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemigatinib After Chemotherapy for the Treatment of Newly Diagnosed Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspirate|PROCEDURE: Bone Marrow Biopsy|DRUG: Cytarabine|DRUG: Daunorubicin|PROCEDURE: Electrocardiography|DRUG: Pemigatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Same-day Versus Rapid ART Initiation in HIV-positive Individuals Presenting With Symptoms of Tuberculosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Immunodeficiency Virus (HIV) Infection
Interventions: OTHER: ART first- Therapeutic use trial|OTHER: TB results first- Therapeutic use trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Appropriate Duration of Anti-Platelet and Thrombotic Strategy After 12 Months in Patients With Atrial Fibrillation Treated With Drug Eluting Stents
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: NOAC monotherapy|DRUG: Dual antithrombotic therapy with NOAC and clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Zanubrutinib (BGB-3111) Versus Ibrutinib in Participants With Relapsed/Refractory Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Zanubrutinib|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Maternal Health Multilevel Intervention for Racial Equity (MIRACLE) Project
Status: ENROLLING_BY_INVITATION
Conditions: Maternal Morbidity and Mortality|Health Disparities
Interventions: OTHER: Multilevel intervention for racial disparities in severe maternal morbidity and mortality|OTHER: Standard Enhanced Prenatal Care (EPC) services
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Rhodiola Rosea for Coronary Microvascular Disease
Status: UNKNOWN
Conditions: Coronary Microvascular Disease
Interventions: DRUG: Rhodiola Rosea Capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Neoadjuvant ArOMatase Inhibitor Therapy for ER+ Breast Cancer (NAOMI)
Status: RECRUITING
Conditions: Breast Cancer|ER Positive Breast Cancer
Interventions: DRUG: Letrozole 2.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PAS in Subacute SCI
Status: ENROLLING_BY_INVITATION
Conditions: Spinal Cord Injuries|Spinal Cord Diseases
Interventions: DEVICE: Paired associative stimulation|DEVICE: Sham paired associative stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Potential Different Properties of Telmisartan Compared to Candesartan in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Telmisartan|DRUG: Candesartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Patient-donor Vaccination in the Context of Allogeneic Bone Marrow Transplant With Post-transplant Cyclophosphamide
Status: TERMINATED
Conditions: Transplant-Related Cancer
Interventions: BIOLOGICAL: Havrix|BIOLOGICAL: PCV13
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes
Status: COMPLETED
Conditions: Type2 Diabetes|Insulin Resistance
Interventions: OTHER: High intensity interval training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Wild Blueberries and Cardiovascular Health in Middle-aged/Older Men and Postmenopausal Women
Status: RECRUITING
Conditions: Hypertension|Aging|Endothelial Dysfunction|Men
Interventions: DIETARY_SUPPLEMENT: Blueberry Powder|DIETARY_SUPPLEMENT: Placebo Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of the Safety and Effectiveness of LY3053102 in Participants With Type 2 Diabetes
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: LY3053102|DRUG: Exenatide ER|DRUG: Placebo|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predicting Esophageal Cancer Borders Using PET-Imaging
Status: RECRUITING
Conditions: Esophagus Cancer, Stage I|Esophagus Cancer, Stage II
Interventions: RADIATION: photon|PROCEDURE: surgical therapy|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Study of Oral Ixazomib (MLN9708) in Relapsed/Refractory Multiple Myeloma and Advanced Solid Tumors Participants With Normal Renal Function or Severe Renal Impairment
Status: COMPLETED
Conditions: Multiple Myeloma|Advanced Solid Tumors
Interventions: DRUG: Ixazomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cooling Strategies for Older Adults in the Heat
Status: RECRUITING
Conditions: Aging
Interventions: OTHER: Intermittent cold-water hand and forearm immersion|OTHER: No intermittent cold-water hand and forearm immersion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pigment Dispersion Syndrome: Natural History and Possible Protective Effect of a YAG Laser Iridotomy
Status: COMPLETED
Conditions: Pigment Dispersion Syndrome
Interventions: PROCEDURE: Yag laser iridotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: CV301 Combined With PD-1/L1 Blockade in Patients With Locally Advanced or Metastatic Urothelial Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: BIOLOGICAL: CV301|BIOLOGICAL: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of a Mobile Application in Reducing Craving and Lapse Risk in Alcohol and Stimulants Problematic Use
Status: UNKNOWN
Conditions: Addiction|Addiction, Alcohol|Addiction, Substance
Interventions: OTHER: mobile app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Intubating Condition of the Mcgrath Videolaryngoscope With and Without Muscle Relaxant
Status: COMPLETED
Conditions: Muscle Relaxant
Interventions: DEVICE: Videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Antibiotic Treatment of Moderate to Severe Bacterial Infections
Status: COMPLETED
Conditions: Community-associated Infections|Health-care Acquired Infections|Nosocomial Infections
Interventions: OTHER: antibiotic treatment of by TREAT/PCR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breast Cancer Treated by Neoadjuvant Chemotherapy
Status: COMPLETED
Conditions: Individualized Chemotherapy
Interventions: DRUG: Taxotere|DRUG: 5-Fluorouracil|DRUG: Epirubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AIMN Multicenter Study: 18 F-FDG PET-CT With or Without Contrast Medium in the Staging and Radiation of Lung Cancer?
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DIAGNOSTIC_TEST: PET/CT with contrast medium in a single session.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Comparative Effectiveness Research Trial of Three Treatments for COPD Patients
Status: UNKNOWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Salbutamol (Ventolin®)|DRUG: Formoterol (Oxis Turbuhaler®)|DRUG: Salmeterol / fluticasone (Seretide®)|DRUG: Bufei granule|DRUG: Bufeijianpi granule|DRUG: Bufeiyishen granule|DRUG: Yiqizishen granule|DRUG: conventional medicine + TCM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dual PD-1 and JAK2 Inhibition in Hematological Malignancies
Status: WITHDRAWN
Conditions: Cancer|Hematological Malignancy
Interventions: DRUG: Pembrolizumab|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic Testing for Breast, Ovarian, Pancreatic, and Prostate Cancers
Status: COMPLETED
Conditions: Breast Cancer|Ovarian Cancer|Pancreatic Cancer|Metastatic Prostate Cancer
Interventions: BEHAVIORAL: Standard Genetic Counseling|BEHAVIORAL: Educational Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of JNJ-64042056 in Participants With Preclinical Alzheimer's Disease
Status: RECRUITING
Conditions: Preclinical Alzheimer's Disease
Interventions: DRUG: JNJ-64042056|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Trauma Recovery and Empowerment Model for Treating Post-Traumatic Stress Disorder in Women
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder|Mental Disorders|Depression
Interventions: BEHAVIORAL: Trauma Recovery and Empowerment Model (TREM)|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Dabigatran Etexilate Capsules 150 mg in Healthy Thai Volunteers Under Fasting Conditions
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteer|Dabigatran|Bioequivalence Study
Interventions: DRUG: Dabigatran Etexilate Capsules 150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: High-Dose 3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Consolidation of First Remission After Myeloablative Therapy and Autologous Stem-Cell Transplantation
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: 3F8 monoclonal antibody and 13-cis-Retinoic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Teclistamab (TECVAYLI) in Combination With Iberdomide for Hard-to-Treat Multiple Myeloma
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|DRUG: Iberdomide|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|DRUG: Teclistamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Left Atrial Strain and Supraventricular Arrhythmia Burden in Cardiac Light Chain Amyloidosis Following Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Supraventricular Arrhythmia|Left Atrial Abnormality|Amyloid Cardiomyopathy|Congestive Heart Failure
Interventions: DIAGNOSTIC_TEST: Left Atrial Strain Imaging|DIAGNOSTIC_TEST: Electrocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: FIRST-NEC (GFPC 01-2022) - Combination of Durvalumab With Etoposide and Platinum
Status: RECRUITING
Conditions: Large Cell Neuroendocrine Carcinoma of the Lung
Interventions: DRUG: Durvalumab with etoposide and Carboplatin/Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet-rich Plasma Injections and Physiotherapy in the Treatment of Chronic Rotator Cuff Tendinopathy
Status: COMPLETED
Conditions: PRP Injection Only|Physiotherapy Only|PRP and Physiotherapy
Interventions: OTHER: PRP preparation|DEVICE: Physiotherapy|OTHER: PRP and physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Injection Technique Assessment of Restylane Lyft With Lidocaine for Cheek Augmentation
Status: COMPLETED
Conditions: Cheek Augmentation|Midface Contour Deficiencies
Interventions: DEVICE: Restylane Lyft with Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin on Inflammation and Cardiac Function in Chronic Chagas Disease
Status: RECRUITING
Conditions: Chronic Chagas Disease
Interventions: DRUG: 40 mg Atorvastatin/day for 120 days P.O.|DRUG: Atorvastatin 80|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Azacitidine Plus Deferasirox (ICL670) in Higher Risk Myelodysplastic Syndromes (MDS)
Status: TERMINATED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Deferasirox + Azacitidine|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Differential Effects of a Diet Supplementation With Plant Sterol Esters on Human Monocytes
Status: UNKNOWN
Conditions: Hyperlipidemia
Interventions: DIETARY_SUPPLEMENT: margarine + plant sterol esters|DIETARY_SUPPLEMENT: margarine (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of MK0736 & MK0916 in Patients With Hypertension (High Blood Pressure)(0736-003)(COMPLETED)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: MK0736|DRUG: MK0916|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuation Study of Lapatinib Monotherapy or Lapatinib in Combination With Other Anti-cancer Agents
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: Lapatinib in combination with an anti-cancer agent|DRUG: Lapatinib|DRUG: Lapatinib in combination with an anti-cancer agent as specified by parent protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunological and Histological Evaluation of Specific Immunotherapy With Recombinant Hypoallergenic Derivative
Status: COMPLETED
Conditions: Allergic Rhinoconjunctivitis
Interventions: OTHER: Placebo|BIOLOGICAL: rBet v1-FV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Emotion Regulation Training Via Telehealth During the COVID-19 Pandemic
Status: ACTIVE_NOT_RECRUITING
Conditions: Distress, Emotional|Emotional Dysfunction|Anxiety|Depression
Interventions: BEHAVIORAL: Emotion Regulation Training via Telehealth
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Native American Diabetes Project
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes|Diabete Type 2|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Diabetes Type 1|Diabetes Mellitus
Interventions: BEHAVIORAL: Virtual Diabetes Wellness Classes and Medically Tailored Meals
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparison of Injection Pain of Propofol During Endoscopy : LCT Propofol vs MCT/LCT Propofol
Status: COMPLETED
Conditions: Pain|Complication of Injection
Interventions: DRUG: Fresofol|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Steroids Helping Albuterol Responders Exclusively
Status: WITHDRAWN
Conditions: Bronchiolitis
Interventions: DRUG: prednisolone or methylprednisolone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Chlorhexidine Wipe for Prevention of Multidrug-resistant Organisms in Intensive Care Unit Patients
Status: COMPLETED
Conditions: Antibiotic Resistant Infection
Interventions: DRUG: 2% chlorhexidine wipe|DRUG: Soap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Stellate Nerve Block in Dysphagia
Status: COMPLETED
Conditions: Dysphagia
Interventions: PROCEDURE: Injection|DRUG: Lidocaine Hydrochloride|BEHAVIORAL: Comprehensive therapy|BEHAVIORAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The ARUTIS Study (Anglia Ruskin University Trial of the Intuitive System)
Status: RECRUITING
Conditions: Visual Stress
Interventions: DEVICE: Tinted Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retraining Attention to Treat Alcohol Dependence and Social Anxiety
Status: COMPLETED
Conditions: Alcohol Drinking|Anxiety Disorders
Interventions: BEHAVIORAL: Anxiety Attention Training|BEHAVIORAL: Alcohol Attention Training|BEHAVIORAL: Control Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Statin Therapy on Adaptations to Aerobic Exercise
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Diseases
Interventions: DRUG: Lipitor 20Mg Tablet|DRUG: Lipitor 80Mg Tablet|DRUG: Placebo|BEHAVIORAL: Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Benefits of Immersive Virtual Reality on Dyspnoea During a Weaning Test in the Intensive Care Unit.
Status: NOT_YET_RECRUITING
Conditions: Spontaneous Breathing Trial in ICU
Interventions: DEVICE: Immersive virtual reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Decellularised Dermis Allograft for the Treatment of Chronic Venous Leg Ulceration
Status: TERMINATED
Conditions: Venous Ulcer|Allograft
Interventions: OTHER: dCELL® Human Dermis (decellularised dermal skin allograft - DCD)|OTHER: Compression bandaging therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Preconditioning With Postconditioning in Heart Transplantation Surgery
Status: COMPLETED
Conditions: Myocardial Ischemic Reperfusion Injury|End Stage Heart Disease|Heart Failure|Cardiomyopathy
Interventions: PROCEDURE: RIPC+RIPostC|PROCEDURE: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vagus Nerve-guided Robotic-assisted Splenectomy and Azygoportal Disconnection
Status: COMPLETED
Conditions: Cirrhosis|Hypertension|Splenectomy|Robotic-assisted
Interventions: PROCEDURE: vagus nerve-guided group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Armodafinil Treatment in Improving Prefrontal Cortical Activation and Working Memory Performance
Status: COMPLETED
Conditions: Excessive Sleepiness
Interventions: DRUG: Armodafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-articular Corticosteroid Injection in GAE for Knee Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis|Pain, Musculoskeletal
Interventions: PROCEDURE: Geniculate Artery Embolization with Intra-articular Corticosteroid Injection (GAE with IACI)|PROCEDURE: Geniculate Artery Embolization alone (GAE alone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Radioiodine Incorporation Into Radio Iodine Refractory Thyroid Cancers With MAPK Inhibition
Status: RECRUITING
Conditions: Metastatic Thyroid Cancer
Interventions: DRUG: Trametinib 2 MG [Mekinist]|DRUG: Trametinib 2 MG [Mekinist] and Dabrafenib 75 MG (2-0-2) [Tafinlar]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Versus Constraint-induced Movement on Hemiparesis in Cerebrovascular Event
Status: RECRUITING
Conditions: Stroke Sequelae
Interventions: BEHAVIORAL: Virtual reality|BEHAVIORAL: Modified constraint-induced movement therapy|BEHAVIORAL: Usual Physical and Occupational Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Virtual Reality Training on Mental Health Literacy and Stigma
Status: NOT_YET_RECRUITING
Conditions: Mental Health Disorder|Literacy|Stigma, Social
Interventions: OTHER: Vırtual Realıty Traınıng On Mental Health Lıteracy And Stıgma|OTHER: Classical Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Short Term Effects of a Hibiscus Sabdariffa and Stevia Rebaudiana Drink on Cardiac Relaxation and Urinary Albumin Excretion in a Group of Diabetic Type 2 Subjects
Status: COMPLETED
Conditions: Benefits of a Hibiscus Sabdariffa and Stevia Rebaudiana Drink in Patients With Type 2 Diabetes Mellitus Before and After 8 Weeks of add-on Therapy
Interventions: DIETARY_SUPPLEMENT: HIBISTEVER1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Superior Hypogastric Plexus Block Versus Pulsed Radiofrequency for Chronic Pelvic Cancer Pain
Status: UNKNOWN
Conditions: Chronic Pelvic Cancer Pain
Interventions: PROCEDURE: superior hypogastric plexus block|RADIATION: pulsed radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Role of Icotinib in the Perioperative Treatment of IIIA - IIIB NSCLC Patients With EGFR Mutation
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer(NSCLC)
Interventions: DRUG: Icotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pioglitazone on Viral Kinetics, Cytokines and Innate Immunity in Insulin Resistant CHC GT 1 Subjects
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Pioglitazone (Actos)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Evaluating Panitumumab (ABX-EGF) Monotherapy in Patients With Metastatic Colorectal Cancer Following Treatment With Fluoropyrimidine, Irinotecan, and Oxaliplatin Chemotherapy
Status: COMPLETED
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: BIOLOGICAL: Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT