pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: P. Knowlesi Trial of Artemether-lumefantrine vs Chloroquine
Status: COMPLETED
Conditions: Uncomplicated Knowlesi Malaria
Interventions: DRUG: Artemether-lumefantrine combination|DRUG: Chloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Multivitamin/Multimineral/Phytochemical Dietary Supplement on Indices of Human Health
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: MVM/phytochemical supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Laparoscopic Assisted Pull-through Versus Other Surgical Procedures for Treatment of Hirschsprung Disease
Status: UNKNOWN
Conditions: Hirschsprung Disease
Interventions: PROCEDURE: laparoscopic assisted pull-through oeration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Telbivudine With or Without add-on Tenofovir According to Roadmap Strategy Compare With Entecavir
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Telbivudine|DRUG: Tenofovir|DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Microcirculatory Characteristics of the Heart and Lung Meridians: A Study of CSAP Patients and Healthy Adults
Status: UNKNOWN
Conditions: Chronic Stable Angina Pectoris
Interventions: OTHER: Moxibustion|DEVICE: Laser doppler flowmetry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Estimate Safety and Efficacy of Sorafenib (BAY43-9006) in the Treatment of Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-Dose Bioequivalence Study Comparing Two 4 mg Nicotine Lozenges
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Nicotine lozenge|DRUG: Nicotine lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Intensive Molecular and Electropathological Characterization of Patients Undergoing Atrial Fibrillation Ablation
Status: UNKNOWN
Conditions: Atrial Fibrillation|Atrial Fibrillation Paroxysmal|Atrial Fibrillation, Persistent
Interventions: PROCEDURE: Pulmonary vein isolation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: In the Prediction of Recurrence and Progression of NMIBC; EORTC or CUETO or Both?
Status: COMPLETED
Conditions: Bladder Cancer|Disease Progression|Recurrent Bladder Cancer
Interventions: PROCEDURE: Intravesical BCG instillation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FOCUS- Frailty Management Optimization Through EIP AHA Commitments and Utilization of Stakeholders Input
Status: UNKNOWN
Conditions: Frailty
Interventions: DIETARY_SUPPLEMENT: Diet /nutritional|BEHAVIORAL: Physical activity|COMBINATION_PRODUCT: Comprehensive therapy|BEHAVIORAL: Caregivers of elderly
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Zimberelimab Plus Metformin for Recurrent Ovarian Clear Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Ovarian Clear Cell Carcinoma
Interventions: DRUG: Zimberelimab|DRUG: Metformin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Goserelin Plus Fulvestrant Comparing With Goserelin Plus Anastrozole for Advanced Breast Cancer
Status: UNKNOWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Fulvestrant|DRUG: Goserelin|DRUG: Anastrozole|DRUG: Goserelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of 12-week Dietary Intake of Food Supplements Containing Collagen on Dermis Density and Other Skin Parameters
Status: COMPLETED
Conditions: Dermis Density|Wrinkles|Skin Hydration|Trans Epidermal Water Loss (TEWL)|Dermis Thickness|Skin Texture|Skin Elasticity
Interventions: DIETARY_SUPPLEMENT: Investigational product 1|DIETARY_SUPPLEMENT: Placebo syrup|DIETARY_SUPPLEMENT: Investigational product 2|DIETARY_SUPPLEMENT: Investigational product 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Surgical Handling and Performance of the X-ray-based Tracking and Navigation System "Xin1 Humerus System" Evaluated From 10 Proximal Humerus Plate Fixations
Status: COMPLETED
Conditions: Proximal Humeral Fracture
Interventions: DEVICE: Xin1 Humerus System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Maqui Berry Extract and Omega-3 Fatty Acids for Cytokine Reduction
Status: COMPLETED
Conditions: Inflammation
Interventions: DIETARY_SUPPLEMENT: Maqui berry/omeg-3 fatty acids|DIETARY_SUPPLEMENT: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Bacterial Contamination: Iodine vs Saline Irrigation in Pediatric Spine Surgery
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: DRUG: Povidone-Iodine|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Mellow Bumps RCT - Antenatal Intervention for Vulnerable Women
Status: COMPLETED
Conditions: Mental Health Wellness 1|Pregnancy|Mother-Child Relations
Interventions: OTHER: Mellow Bumps|OTHER: Chill-out in Pregnancy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Tirzepatide (LY3298176) in Chinese Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Type 2|Diabetes Mellitus|Glucose Metabolism Disorders|Metabolic Disease|Endocrine System Diseases
Interventions: DRUG: Tirzepatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility, Safety and Performance Evaluation of an Application Based Training Programme for Patients After a Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: DEVICE: TeleRehaStroke: Training programme using the 'Blended Clinic' mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Temozolomide in Treating Patients With Leptomeningeal Metastases From a Solid Tumor or Lymphoma
Status: TERMINATED
Conditions: Brain Tumors|Central Nervous System Tumors|Leptomeningeal Metastases
Interventions: DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Osteoporosis Prevention Strategy in Women With Osteoporotic Fracture of the Upper Limb
Status: COMPLETED
Conditions: Osteoporosis With Current Fragility Fracture
Interventions: BEHAVIORAL: Osteoporosis prevention program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Arachidonic Acid-induced Platelet Aggregation Rate in Patients With Stable CAD Treated With Ticagrelor Monotherapy
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DRUG: ticagrelor|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Value of Workload Analysis Instrument to Detect Occupational Risks of Upper Limb Musculoskeletal Conditions
Status: UNKNOWN
Conditions: Musculoskeletal Disease|Occupational Exposure
Interventions: DIAGNOSTIC_TEST: Análisis de carga de trabajo (ACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial of pDNA CMV Vaccine (VCL-CT02) Followed by Towne CMV Vaccine (Towne) Challenge
Status: COMPLETED
Conditions: Cytomegalovirus Infection
Interventions: BIOLOGICAL: VCL CT02 pDNA vaccine|BIOLOGICAL: Towne CMV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intranasal Dexmedetomidine Sedation for Ophthalmic Examinations in Children
Status: UNKNOWN
Conditions: Sniffs Drugs
Interventions: DRUG: intranasal dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study in Subjects With Renal Impairment Compared to Subjects With Normal Renal Function
Status: COMPLETED
Conditions: Subjects With Renal Impairment|Healthy Subjects
Interventions: DRUG: Deuremidevir Hydrobromide Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Medical Device for Airway Patency During Sedation
Status: RECRUITING
Conditions: Airway Obstruction|Sedation Complication|Perioperative Complication
Interventions: DEVICE: STAIRWAY|DEVICE: NO DEVICE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: African-Canadian Study of HIV-Infected Adults and a Vaccine for Ebola - ACHIV-Ebola
Status: ACTIVE_NOT_RECRUITING
Conditions: Ebola
Interventions: BIOLOGICAL: V920 (rVSVΔG-ZEBOV-GP) Ebola Virus Vaccine|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Novel Myocardial Impedance Mapping System for Ablation of Post-infarction Ventricular Arrhytmias in Humans
Status: UNKNOWN
Conditions: Ventricular Arrythmia|Infarction, Myocardial
Interventions: DEVICE: CardioZ multifrequency impedance recording system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Telmisartan/Hydrochlorothiazide (HCTZ) Fixed Dose Combination Compared to Its Monocomponents in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBR 277 SE and HCTZ|DRUG: BIBR 277 SE|DRUG: HCTZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Alogliptin With Pioglitazone (Actos®) in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Alogliptin|DRUG: Pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-hospital Administration of Lyophilized Plasma for Post-traumatic Coagulopathy Treatment (PREHO-PLYO)
Status: COMPLETED
Conditions: Shock Hemorrhagic
Interventions: BIOLOGICAL: French Lyophilized Plasma|BIOLOGICAL: Normale Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Subsequent Treatment With the Zevalin (Ibritumomab Tiuxetan) in Elderly (More Than 60 Years) Patients With Diffuse Large B Cell Lymphoma After 4 Cycles of CHOP21-Rituximab (CHOP21-R) Therapy
Status: COMPLETED
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: CHOP21-R|DRUG: Zevalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Aggressive Non-Hodgkin Lymphoma|Chronic Lymphocytic Leukemia|Diffuse Large B-Cell Lymphoma|Hematopoietic and Lymphoid Cell Neoplasm|Indolent Non-Hodgkin Lymphoma|Mantle Cell Lymphoma|Myelodysplastic Syndrome|Myeloproliferative Neoplasm|Prolymphocytic Leukemia|Recurrent Chronic Lymphocytic Leukemia|Recurrent Plasma Cell Myeloma|Refractory Chronic Lymphocytic Leukemia|Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Refractory Hodgkin Lymphoma|Small Lymphocytic Lymphoma|T-Cell Chronic Lymphocytic Leukemia|Waldenstrom Macroglobulinemia
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Cyclosporine|DRUG: Fludarabine Phosphate|DRUG: Mycophenolate Mofetil|PROCEDURE: Peripheral Blood Stem Cell Transplantation|DRUG: Sirolimus|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Trial of 90Y-Clivatuzumab Tetraxetan & Gemcitabine vs Placebo & Gemcitabine in Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Metastatic Pancreatic Cancer|Pancreatic Cancer
Interventions: DRUG: IMMU-107|DRUG: placebo|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: P2Y12 Inhibitor Monotherapy Versus Extended DAPT in Patients Treated With Bioresorbable Scaffold
Status: TERMINATED
Conditions: Coronary Artery Disease|Stents|Atherosclerosis
Interventions: DRUG: Clopidogrel|DRUG: Ticagrelor|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Influencing Variables in Awakening Concentration and Concentration at Body Movements of Propofol TCI (Targeted Controlled Infusion) Targeted at the Effector Site
Status: COMPLETED
Conditions: Awareness, Anesthesia
Interventions: DRUG: We do not modify the normale general anesthesia delivery. We note the concentration of propofol at the effector site of body movementsand awakening
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Determine the Safety and Efficacy of Liquid ROTAVAC 5C Vaccine Against Childhood Diarrhea Caused by Rotavirus
Status: COMPLETED
Conditions: Rotavirus Gastroenteritis
Interventions: BIOLOGICAL: ROTAVAC®|BIOLOGICAL: ROTAVAC 5C -F1|BIOLOGICAL: ROTAVAC 5C -F2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Research Study To Assess The Effectiveness And Safety Of Different Doses Of Oral PF-00489791 In The Treatment Of Adult Patients With Pulmonary Arterial Hypertension
Status: TERMINATED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: PF-00489791|DRUG: PF-00489791|DRUG: PF-00489791|DRUG: PF-00489791|DRUG: PF-00489791|DRUG: placebo|DRUG: sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of HEPLISAV™ Hepatitis B Virus Vaccine in End-stage Kidney Failure Patients
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: 1018 ISS immunostimulatory oligonucleotide with HBV surface antigen|BIOLOGICAL: Hepatitis B Vaccine (Recombinant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized, Parallel Group, Placebo Control, Unicentric, Interventional Study to Assess the Effect of Expanded Human Allogeneic Adipose-derived Mesenchymal Adult Stem Cells on the Human Response to Lipopolysaccharyde in Human Volunteers
Status: COMPLETED
Conditions: Sepsis
Interventions: OTHER: Intravenous infusion of cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Intelligent Evaluation of Wrist Strength for the Elderly People and Its Clinical Application
Status: UNKNOWN
Conditions: Evaluation of Wrist Muscle Strength
Interventions: DEVICE: Forearm supporter|DEVICE: Grip ball
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bihemispheric Modulation of the Motor Cortex by Transcranial Direct Current Stimulation in Subacute Stroke Patients
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: Magstim Eldith DC-stimulator(Magstim Co., Whitland, UK)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Ascending-Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics of DC371739 Single-Dose Treatment in Healthy Subjects
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: DC371739|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: REVOLVE or PureGraft Technique in Processing Fat Grafts for Patients Undergoing Breast Reconstruction
Status: COMPLETED
Conditions: Mammoplasty Patient
Interventions: OTHER: Questionnaire Administration|PROCEDURE: Reconstructive Surgery|PROCEDURE: Reconstructive Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PTEN-AKT-FOXO3 Gene Expression Relation With Low-ovarian Reserve in Endometriomas
Status: UNKNOWN
Conditions: Ovarian Reserve, Endometrioma, PTEN-AKT-FOXO3 Gene Expression
Interventions: GENETIC: PTEN-AKT-FOXO3 Gene Expression
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of BMS-986360/CC-90001 Alone and in Combination With Chemotherapy or Nivolumab in Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: BMS-986360|DRUG: Docetaxel|DRUG: Nivolumab|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy in Treating Patients With Stage 0-II Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Adenocarcinoma|Ductal Breast Carcinoma In Situ|Invasive Breast Carcinoma|Stage 0 Breast Cancer AJCC v6 and v7|Stage I Breast Cancer AJCC v7|Stage IA Breast Cancer AJCC v7|Stage IB Breast Cancer AJCC v7|Stage II Breast Cancer AJCC v6 and v7|Stage IIA Breast Cancer AJCC v6 and v7|Stage IIB Breast Cancer AJCC v6 and v7
Interventions: RADIATION: Accelerated Partial Breast Irradiation|RADIATION: Proton Beam Radiation Therapy|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Randomized Study of the Efficacy, Safety, and Toleration of Fluconazole Oral Suspension or Nystatin Oral Suspension in the Treatment of Patients With Oropharyngeal Candidiasis in Association With the Acquired Immunodeficiency Syndrome
Status: COMPLETED
Conditions: Candidiasis, Oral|HIV Infections
Interventions: DRUG: Nystatin|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Stress, Hormones, and Eating
Status: COMPLETED
Conditions: Food Addiction|How Opioid Tone Was Related to Self Reported|Drive to Eat Using a Measure of Food Addiction
Interventions: DRUG: Naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of MR-guided LITT Therapy in Irresectable Glioblastoma (EMITT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Glioblastoma
Interventions: PROCEDURE: Laser Interstitial Thermal Therapy (LITT)|PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cilengitide and Cetuximab in Combination With Platinum-based Chemotherapy as First-line Treatment for Subjects With Advanced Non Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Cilengitide|DRUG: Cilengitide|DRUG: Cetuximab|DRUG: Cisplatin|DRUG: Cisplatin|DRUG: Gemcitabine|DRUG: Vinorelbine|DRUG: Cilengitide|DRUG: Cilengitide|DRUG: Cetuximab|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial on Clinical Management of ASCUS and LSIL (ALTS)
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia
Interventions: DEVICE: Thinprep|DEVICE: Hybrid capture 2|PROCEDURE: Colposcopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: The Influence of Two Different Hepatectomy Methods on Transection Speed and Chemokine Release From the Liver
Status: COMPLETED
Conditions: Liver Neoplasms|Liver Metastasis|Liver Hemangioma|Echinococcosis, Hepatic
Interventions: DEVICE: Stapler|DEVICE: CUSA (Cavitron ultrasonic aspirator; Valleylab, Boulder, CO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Single Ascending Doses of Subcutaneous Exendin 9-39 in Patients With Post-Bariatric Hypoglycemia
Status: UNKNOWN
Conditions: Hyperinsulinemia Hypoglycemia
Interventions: DRUG: Exendin (9-39)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate Pharmacokinetic Profiles and Safety Between CKD-385 and D935 in Healthy Volunteers
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: D935 Cap. 1T|DRUG: CKD-385 Tab. 1T
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding Food Choices
Status: COMPLETED
Conditions: Diet Quality
Interventions: BEHAVIORAL: Explicit Tax|BEHAVIORAL: Food Labels (with the summary of healthiness of shopping baskets & targets)|BEHAVIORAL: Ordering|BEHAVIORAL: Within-Group Substitution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Identification and Evaluation of Patients at Risk of Developing Cardiotoxicity After Receiving Chemotherapy for Breast Cancer, Lymphoma or Leukemia
Status: RECRUITING
Conditions: Breast Cancer|Lymphoma|Leukemia
Interventions: DIAGNOSTIC_TEST: Cardiac Imaging|OTHER: Data Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Modified Immune Cells (CD19 CAR T Cells) and Acalabrutinib for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma
Status: RECRUITING
Conditions: Recurrent Mantle Cell Lymphoma|Refractory Mantle Cell Lymphoma
Interventions: DRUG: Acalabrutinib|BIOLOGICAL: CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/mem-enriched T-lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Multidisciplinary Assessment in Day Hospitalization Versus Standard Care on the Deployment of Supportive Oncology Care Recommended by the Personalized Post-cancer Plan in Patients at the End of Initial Treatment for Gynecological Ovarian and Endometrial Cancer Endometrial Cancer
Status: RECRUITING
Conditions: Gynecologic Cancer|Remission
Interventions: OTHER: Multidisciplinary assessment|OTHER: Standard assesment|OTHER: Observational cohort
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Evaluating the Efficacy of QGE031 Compared to Omalizumab in Patients With Allergic Asthma
Status: COMPLETED
Conditions: Allergic Asthma
Interventions: DRUG: QGE031|DRUG: omalizumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bag Mode BreathID Hp Validation Versus Endoscopy in Detection of Helicobacter Pylori
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: OTHER: Breath Test Collection bags
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Ph 2/3 Study in Subjects With MPM to Assess ADI-PEG 20 With Pemetrexed and Cisplatin
Status: COMPLETED
Conditions: Mesothelioma
Interventions: DRUG: ADI-PEG 20 plus Pem Platinum|OTHER: Placebo plus Pem Platinum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Physical Activity for Hemodialysis Patients
Status: UNKNOWN
Conditions: End Stage Renal Disease on Hemodialysis
Interventions: BEHAVIORAL: Intradialytic exercise on stationary bicycles|BEHAVIORAL: Non-exercising group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food Study of Pioglitazone HCl Tablets 45 mg to Actos® Tablets 45 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pioglitazone HCl Tablets 45 mg|DRUG: Actos® Tablets 45 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Proton Magnetic Spectroscopy in Children and Adolescents With ADHD Before and After Treatment With OROS Methylphenidate
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: OROS methylphenidate|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Randomized Study For Minimally Invasive Splinted Implants
Status: COMPLETED
Conditions: Jaw, Edentulous
Interventions: DEVICE: Integrated system to insert two splinted (bar) mini dental implants for mandibular overdenture|OTHER: Denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Training Protocol With the Cervical Device in Subjects With Deep Cervical Muscle Strength Deficit.
Status: COMPLETED
Conditions: Muscle Weakness|Cervical Disability
Interventions: OTHER: Training protocol with the device cervical for treatment (CDAT)|OTHER: Conventional training protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Veterans Individual Placement and Support Towards Advancing Recovery
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: BEHAVIORAL: Individual Placement & Support|BEHAVIORAL: VA Transitional Work Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Muscle Function and Its Biological and Physiological Determinants in Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: BIOLOGICAL: Blood sampling|OTHER: Maximum Voluntary Contraction (MVC) test force|OTHER: Localized muscle endurance test|OTHER: Self-paced six-minute walk test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: QOL in Incarcerated Inguinal Hernias: TAPP Vs Open Repair
Status: UNKNOWN
Conditions: Inguinal Hernia
Interventions: PROCEDURE: Open modified Lichtenstein repair|PROCEDURE: Laparoscopic TAPP inguinal hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study With SCB-313 (Recombinant Human TRAIL-Trimer Fusion Protein) for Treatment of Malignant Ascites
Status: COMPLETED
Conditions: Malignant Ascites
Interventions: DRUG: SCB-313
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ARGX-110 in Combination With Azacytidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) or High Risk Myelodysplatic Syndrome (MDS)
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute|Myelodysplastic Syndromes
Interventions: DRUG: ARGX-110|DRUG: AZA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient-controlled Sedation With Propofol and Remifentanyl for Endoscopic Retrograde Cholangiopancreatography (ERCP)
Status: COMPLETED
Conditions: Endoscopic Retrograde Cholangiopancreatography
Interventions: DEVICE: infusion pump|DEVICE: infusion pump for patient-controlled sedation|DRUG: propofol|DRUG: fentanyl|DRUG: sedative mixture|DRUG: remifentanil hydrochlorid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test How a New Long-acting Insulin Works in the Body of Patients With Type 2 Diabetes During Exercise and Prolonged Fasting
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin icodec|DRUG: Insulin degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EACA VS CCA in Postoperative Evaluation of Middle Ear Pressure
Status: NOT_YET_RECRUITING
Conditions: Adenoid Hypertrophy
Interventions: PROCEDURE: Adenoidectomy with endoscopic assisted coblation (EACA) and Adenoidectomy with conventional curettage (CCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Cognitive-motor Exercise for Stroke Patients in Function, Cognition and Related Brain Changes.
Status: RECRUITING
Conditions: Stroke
Interventions: BEHAVIORAL: Dual-task training|BEHAVIORAL: Single-task training|BEHAVIORAL: Upper limb strengthening exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation Of Marginal Bone Loss In Implants With Different Surface Properties And Geometric Designs: A Retrospective Clinical Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Implant Infection|Peri-Implantitis|Bone Loss
Interventions: OTHER: dental implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Personalized Targeted Inhibitors Treatment in Renal Cell Cancer
Status: TERMINATED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Sunitinib|DRUG: Temsirolimus|DRUG: Sorafenib|DRUG: Pazopanib|DRUG: Everolimus|DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study to Evaluate the Safety of a New Monovalent Intranasal Influenza Vaccine
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Monovalent influenza virus vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Febuxostat for Tumor Lysis Syndrome Prevention in Hematological Malignancies of Paediatric Patients and Adults
Status: TERMINATED
Conditions: Tumor Lysis Syndrome
Interventions: DRUG: Febuxostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial on the GI of Spaghetti Versus Rice as Mixed Meals
Status: COMPLETED
Conditions: Dietary Modification
Interventions: OTHER: Glucose #1|OTHER: Glucose #2|OTHER: Glucose #3|OTHER: Spaghetti|OTHER: Rice|OTHER: Spaghetti + Tomato Sauce|OTHER: Rice + Tomato Sauce|OTHER: Spaghetti + Pesto|OTHER: Rice + Pesto
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Safe Use and Tolerance of a Peptide-based Formula in a Pediatric Population
Status: COMPLETED
Conditions: Gastrointestinal Diseases|Feeding Intolerance
Interventions: OTHER: Peptide based enteral formula
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MR-Guided Focused Ultrasound (MRgFUS) for the Management of Tremor in Patients With Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: DEVICE: Focused Ultrasound (MRgFUS) for the Management of Tremor in Patients With Multiple Sclerosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Midodrine for the Early Liberation of Vasopressor Support in the ICU (LIBERATE Multi-Site)
Status: RECRUITING
Conditions: Vasoplegia
Interventions: DRUG: Midodrine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Bioavailability of Pembrolizumab (MK-3475) Via Subcutaneous (SC) Injection of MK-3475A (Pembrolizumab Formulated With MK-5180) In Advanced Solid Tumors (MK-3475A-C18)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced or Metastatic Solid Tumors
Interventions: BIOLOGICAL: MK-3475A|BIOLOGICAL: Pembrolizumab|DRUG: Pemetrexed|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Nab-paclitaxel|DRUG: Axitinib|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effectiveness of Craniosacral Therapy in Patients With Multiple Sclerosis.
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: Craniosacral therapy|OTHER: Conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluorouracil With or Without Mitomycin in Treating Patients With Peritoneal Cancer
Status: UNKNOWN
Conditions: Carcinoma of the Appendix|Colorectal Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: chemotherapy|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of TwHF and MTX in Patients With Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Treatment of MTX|DRUG: Treatment of MTX and TwHF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thermal Ablation Combined With External Beam Radiation Therapy for Patients With Inoperable Non-Small Cell Lung Cancer > 3.5 cm in Size
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: RADIATION: thermal ablation with external beam radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Efficacy of Ginger Powder as an Analgesic for Intraoperative and Post- Endodontic Pain Management
Status: NOT_YET_RECRUITING
Conditions: Endodontic Disease
Interventions: DRUG: Ginger powder capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Test for Pre Operative Skin Preparations
Status: COMPLETED
Conditions: Topical Antisepsis
Interventions: DRUG: CHG 2% w/v & IPA 70% v/v, swabstick (3 @ once).|DRUG: CHG 2% w/v & IPA 70% v/v swab applied sequentially|DRUG: Aqueous CHG 4% w/v applied according to mfr's directions|OTHER: Sterile swabstick with sterile water (3 @ once)|OTHER: Sterile swabstick with sterile water (one-at-a-time)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Implantation of Bone Marrow Cells to Treat Avascular Necrosis of Femoral Head (ANFH)
Status: UNKNOWN
Conditions: Avascular Necrosis of Femur Head
Interventions: PROCEDURE: core decompression|PROCEDURE: Enriched BMCs implantation combined with core decompression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MK0524A Clinical Efficacy Study (0524A-026)(COMPLETED)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Comparator : placebo (unspecified) / Duraton of Treatment: 4 Weeks|DRUG: MK0524A, niacin (+) laropiprant / Duration of Treatment : 4 Weeks|DRUG: Comparator : niacin / Duraton of Treatment: 4 Weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Collateral Circulation in Patients With Symptomatic Intracranial Anterior Circulation Occlusion
Status: UNKNOWN
Conditions: Collateral Circulation|Large-artery Occlusion|Cerebral Infarction
Interventions: DRUG: Butylphthalide Soft Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Accelerometer Guided App Feedback on Change in Activity in Patients With Low Back
Status: COMPLETED
Conditions: Low Back Pain|Radiculopathy Lumbar|Sciatica
Interventions: DEVICE: The SENS motion® sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety APT-1011 in Adolescent Subjects With Eosinophilic Esophagitis (EoE) - A Sub-Study of the FLUTE-2 Trial
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: APT-1011|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study for Evaluating the Clinical Safety and Effectiveness of the Automated Robotic Robot, Revo-i Surgical Robot System (Model MSR-5100), Used for General Endoscopic Surgery.
Status: UNKNOWN
Conditions: Periampullary Cancer
Interventions: PROCEDURE: Revo-i robotic surgery system (Model MSR-5100)|PROCEDURE: Revo-i robotic surgery system (Model MSR-5100)|PROCEDURE: Revo-i robotic surgery system (Model MSR-5100)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fermented Milk Supplementation on Symptoms of Disease and Treatment in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Plasma Cell Myeloma
Interventions: OTHER: Best Practice|DIETARY_SUPPLEMENT: Kefir|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Pharmacokinetics and Pharmacodynamics of Oral and Vaporized Cannabidiol
Status: COMPLETED
Conditions: Cannabidiol Pharmacokinetics
Interventions: DRUG: Oral or vaporized cannabidiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preventing Alzheimer's With Cognitive Training
Status: RECRUITING
Conditions: Age-related Cognitive Decline|Alzheimer's Disease and Related Dementias
Interventions: BEHAVIORAL: Cognitive Training|BEHAVIORAL: Computerized Cognitive Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Chemotherapy on Muscle Mass and Exercise Performance in Patients With Oesophageal Cancer.
Status: COMPLETED
Conditions: Oesophageal Adenocarcinoma
Interventions: RADIATION: DEXA scan|PROCEDURE: Muscle biopsy|OTHER: cardio-pulmonary exercise testing (CPEX)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Does Early Elbow Motion Improve Patient Outcomes After Surgically Treated Elbow Fractures?
Status: COMPLETED
Conditions: Elbow Fracture|Range of Motion|Immobilization
Interventions: OTHER: Splint Immobilization|OTHER: Early Motion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adults Habitual Patellar Dislocation:a Multiple-center Clinical Investigation Regarding Diagnosis and Therapeutic Strategy
Status: UNKNOWN
Conditions: Habitual Patellar Dislocation
Interventions: PROCEDURE: Four-in-one procedure|PROCEDURE: soft-tissue surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Intervention Program for Preterm Infants and Their Parents: Establishing the Impact at 18 Months Corrected Age
Status: UNKNOWN
Conditions: Complication of Prematurity
Interventions: OTHER: Early stimulation|OTHER: Conventional care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Tele-prehabilitation in Patients Waiting for Knee Replacement
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: OTHER: Tele-prehabilitation|OTHER: Standard prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of MR-107A-02 in the Treatment of Post Surgical Dental Pain.
Status: COMPLETED
Conditions: Acute Pain|Post Operative Pain|Pain
Interventions: DRUG: MR-107A-02|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate SAGE-324 in Participants With Essential Tremor
Status: COMPLETED
Conditions: Essential Tremor
Interventions: DRUG: SAGE-324|DRUG: SAGE-324 Matched Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Addition of Proprioceptive Neuromuscular Facilitation to Cardio Respiratory Training Post Stroke
Status: RECRUITING
Conditions: Stroke|Chest Wall Disorder|Quality of Life
Interventions: OTHER: Lower limbs CRT|OTHER: Upper limbs CRT|OTHER: Proprioceptive Neuromuscular Facilitation|OTHER: respiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anatomy-based Fitting in Cochear Implant Users
Status: RECRUITING
Conditions: Cochlear Implant|Outcomes|Quality of Life
Interventions: PROCEDURE: Anatomy-based fitting (ABF)|PROCEDURE: Standard Fitting|PROCEDURE: Standard fitting+ ABF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Clinical Study to Determine the Safety and Effectiveness of Dentinal Hypersensitivity Treatment With Two Different Toothbrushes
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: DEVICE: Potassium Oxalate|DRUG: Stannous fluoride paste|DEVICE: Manual toothbrush|DEVICE: Power toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Spoton Trial Evaluating the Efficacy on BAlance Disorder sYmptoms (STEADY)
Status: SUSPENDED
Conditions: Balance Disorders
Interventions: DEVICE: SpotOn Specs|DEVICE: Sham Specs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Action Observation Physical Training on Quality of Upper Limb and Functional Independence in Children With Hemiplegia
Status: COMPLETED
Conditions: Hemiplegic Cerebral Palsy
Interventions: OTHER: action observation physical training|OTHER: Traditional physical therapy training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Proximal Humerus Fractures: Randomized Study Between Locking Nails and Locking Plates for Neer 2 and 3 Parts
Status: COMPLETED
Conditions: Humerus|Proximal Humeral Fracture|Fractures, Bone|Humeral Fractures|Wounds and Injuries|Arm Injuries
Interventions: DEVICE: Locked plate|DEVICE: Intramedullary locked nail
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT