pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Progressive Muscle Relaxation Exercises Versus Pilates Exercises on Postnatal Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Progressive Muscle Relaxation Exercises|OTHER: Pilates Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single-dose of Nalmefene to Modulate Neural Alcohol Cue Reactivity
Status: TERMINATED
Conditions: Alcoholism
Interventions: DRUG: Nalmefene|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Test of the Safety, Effectiveness, & Acceptability of An Improvised Dressing for Sickle Cell Leg Ulcers in the Tropics
Status: COMPLETED
Conditions: Sickle Cell Leg Ulcer
Interventions: DEVICE: Usual Practice|DEVICE: Improvised dressing|DEVICE: Advanced dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pericapsular Nerve Group Block
Status: RECRUITING
Conditions: Acute Pain
Interventions: PROCEDURE: Pericapsular Nerve Group Block|PROCEDURE: Fascia iliaca compartment block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Dietary Intervention in Managing Bowel Dysfunction and Improving Quality of Life in Stage I-III Rectosigmoid Cancer Survivors
Status: COMPLETED
Conditions: Cancer Survivor|Stage I Rectosigmoid Cancer|Stage II Rectosigmoid Cancer|Stage III Rectosigmoid Cancer
Interventions: OTHER: Informational Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Survey Administration|BEHAVIORAL: Telephone-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Pitolisant on Excessive Daytime Sleepiness and Other Non-Muscular Symptoms in Patients With Myotonic Dystrophy Type 1
Status: ACTIVE_NOT_RECRUITING
Conditions: Myotonic Dystrophy 1|Excessive Daytime Sleepiness
Interventions: DRUG: Pitolisant Oral Tablet|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Atomoxetine Asian Study in Adult Subjects With Attention-Deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Banana Flower Stamens Extract on Prevention of Benign Prostatic Hyperplasia in Adults
Status: RECRUITING
Conditions: Benign Prostatic Hyperplasia (BPH)
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Banana flower stamens extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lung Function in Patients With Early Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Pulmonary Function
Interventions: DRUG: Calcium Dobesilate|DRUG: Xuefuzhuyu Decoction|DRUG: Xuefuzhuyu Decoction & Calcium dobesilate|DRUG: metformin|DRUG: Mecobalamin Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Recombinant Norovirus Hexavalent Vaccine in Healthy Subjects
Status: NOT_YET_RECRUITING
Conditions: Gastroenteritis
Interventions: BIOLOGICAL: Recombinant Norovirus Hexavalent Vaccine|OTHER: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial Comparing Two Carboplatin Doses in Groups C and D Intraocular Retinoblastoma
Status: UNKNOWN
Conditions: Intraocular Retinoblastoma
Interventions: DRUG: carboplatin|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of N- Acetylcysteine on Inflammatory and Oxidative Stress Biomarkers
Status: UNKNOWN
Conditions: Bipolar Disorder
Interventions: DIETARY_SUPPLEMENT: N-acetyl-cysteine (NAC)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parenting in 2 Worlds Multisite Trial
Status: RECRUITING
Conditions: Parenting|Mental Health Wellness 1|Substance Use|Risky Health Behavior
Interventions: BEHAVIORAL: Parenting in 2 Worlds (P2W)|BEHAVIORAL: Healthy Families in 2 Worlds (HF2W)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase II, Study to Determine the Preliminary Efficacy of Novel Combinations of Treatment in Patients With Platinum Refractory Extensive-Stage Small-Cell Lung Cancer
Status: COMPLETED
Conditions: Platinum Refractory Extensive-Stage Small Cell Lung Carcinoma
Interventions: DRUG: Durvalumab and Tremelimumab|DRUG: AZD1775 and carboplatin (CBPT)|DRUG: AZD6738 and olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Haploidentical Lymphocytes With Nivolumab/Ara-C as Consolidation in Elderly AML Patients
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|DRUG: Nivolumab|DRUG: Cytarabine|DRUG: Nivolumab|BIOLOGICAL: G-CSF mobilized HLA-haploidentical donor PBSC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Intervention to Improve Quality of Life in Patients With Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer|Fatigue|Quality of Life
Interventions: BEHAVIORAL: elastic band training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tranexamic Acid in the Prevention of Postpartum Hemorrhage in Elective Caesarean Section
Status: COMPLETED
Conditions: Postpartum Hemorrhage|Tranexamic Acid
Interventions: DRUG: Tranexamic acid|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Open Label Single-Dose Study to Compare the Pharmacokinetics of NP101 Healthy Volunteers
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: NP101 Sumatriptan Iontophoretic Transdermal Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effects of High Dose Aflibercept Injected Into the Eye of Patients With an Age-related Disorder That Causes Loss of Vision Due to Growth of Abnormal Blood Vessels at the Back of the Eye
Status: ACTIVE_NOT_RECRUITING
Conditions: Neovascular Age-Related Macular Degeneration
Interventions: DRUG: Aflibercept High Dose VEGF Trap-Eye (BAY86-5321)|DRUG: Aflibercept VEGF Trap-Eye (Eylea, BAY86-5321)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Necitumumab in the Neoadjuvant Setting With Gemcitabine in Surgically Resectable - 14X-US-I001
Status: TERMINATED
Conditions: Squamous Cell Lung Cancer
Interventions: DRUG: Necitumumab-Gemcitabine-Cisplatin|DIAGNOSTIC_TEST: Evaluation to determine if patient is a candidate to proceeed with surgical resection or not
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-care Intervention for Reducing Rehospitalization for Heart Failure: a Randomized Clinical Trial (SIHF)
Status: COMPLETED
Conditions: Heart Failure
Interventions: BEHAVIORAL: self-care intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial to Compare the Effectiveness of Two Rehabilitation Programs for Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Combined program|BEHAVIORAL: Physiotherapy in private practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of VICRIVIROC in HIV-Infected Treatment-Naïve Subjects (Study P04875)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Vicriviroc|DRUG: emtricitabine and tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Prevalence and Clinical Impact of Atrial Fibrillation in Elderly Patients With Cryptogenic Stroke and High-Risk Patent Foramen Ovale
Status: RECRUITING
Conditions: Cryptogenic Stroke|High Risk Patent Foramen Ovale
Interventions: PROCEDURE: Percutaneous device closure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Physiotherapy and Corticosteroid Injections in Lateral Epicondylalgia
Status: COMPLETED
Conditions: Tennis Elbow|Musculoskeletal Diseases
Interventions: PROCEDURE: Manual therapy and therapeutic exercise|PROCEDURE: Corticosteroid injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Physiological Parameters Measurements (Heart Rate, Respiratory Rate, and Oxygen Saturation) by Standard Acquisition System Compared Remote Photoplethysmography Imaging System l
Status: UNKNOWN
Conditions: Plethysmography|Remote Photoplethysmography Imaging|Physiological Parameters
Interventions: DEVICE: Remote photoplethysmography for physiological parameters|DEVICE: standard acquisition system for physiological parameters
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Epinastine + Pseudoephedrine SR (Slow Release) Versus Epinastine Alone in Patients With Perennial Allergic Rhinitis
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: Epinastine|DRUG: Pseudoephedrine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Animal Allergy in Korean Pet Owners, Pet-related Industry Workers, and Laboratory Animal Reseachers
Status: COMPLETED
Conditions: Allergic Rhinitis|Allergic Conjunctivitis|Urticaria|Asthma
Interventions: OTHER: Animal allergy|OTHER: Non-animal allergy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acute Medical Admissions of ELDERly Patients (ELDER)
Status: COMPLETED
Conditions: Geriatric Disorder
Interventions: OTHER: QDU|OTHER: DIM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of PRT2527 in Participants With Advanced Solid Tumors
Status: COMPLETED
Conditions: Sarcoma|Castrate Resistant Prostate Cancer|Hormone Receptor Positive HER2 Negative Breast Cancer|Non-small Cell Lung Cancer|Solid Tumors With Known MYC Amplification
Interventions: DRUG: PRT2527
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic Lactobacillus Reuteri to Prevent Antibiotic-associated Diarrhea and Clostridium Difficile-related Infections in Hospitalized Children
Status: COMPLETED
Conditions: Antibiotic Associated Diarrhea|Clostridium Difficile Infection|Gastroenteritis
Interventions: DIETARY_SUPPLEMENT: L reuteri in children on antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Lianhua Qingwen in Treating Patients Infected With the Omicron Variant of the COVID-19
Status: RECRUITING
Conditions: COVID-19 Pneumonia
Interventions: DRUG: The group of patients who received Lianhua Qingwen orally|OTHER: The group of patients who did not receive Lianhua Qingwen orally
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Renal Hemodynamic Effects of the HMG-CoA Reductase Inhibitors in Normal Volunteers and in Patients With Chronic Renal Failure
Status: COMPLETED
Conditions: Hyperlipidemia|Hypertension|Chronic Renal Failure
Interventions: DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Long-Term Immune Persistence of GSK Biologicals' Combined Hepatitis A & B Vaccine Injected According to a 0,1,6 Month Schedule
Status: COMPLETED
Conditions: Hepatitis B|Hepatitis A
Interventions: BIOLOGICAL: Twinrix™ adult
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Multi-centre, Prospective Surveillance to Assess Mid-term Performance of the Mpact Cup
Status: TERMINATED
Conditions: Osteoarthritis|Arthritis|Avascular Necrosis|Fracture of the Femoral Neck or Head|Congenital Hip Dysplasia
Interventions: DEVICE: Mpact Acetabular Shell
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diathermy vs Scalpel in Abdominal Incision in Women Undergoing CS
Status: UNKNOWN
Conditions: Incision, Surgical
Interventions: PROCEDURE: electrosurgery|PROCEDURE: scalpel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Targeted Alpha-Particle Therapy for Advanced SSTR2 Positive Neuroendocrine Tumors
Status: RECRUITING
Conditions: Neuroendocrine Tumors|Neuroendocrine Tumor of the Lung|Neuroendocrine Tumor of Pancreas|Neuroendocrine Carcinoma Metastatic|Neuroendocrine Tumor Carcinoid|Carcinoid Tumor of GI System|Carcinoid Tumor|Paraganglioma|Pheochromocytoma|Small-cell Lung Cancer
Interventions: DRUG: [212Pb]VMT-α-NET|DRUG: [212Pb]VMT-α-NET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Effect of Formulation and Food on the Pharmacokinetics of GDC-0810
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: GDC-0810 Phase II Tablet|DRUG: GDC-0810 Phase III Prototype Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety of Recombinant Human Papillomavirus Bivalent (Types 16 and 18) Vaccine (Yeast) in Healthy Females
Status: UNKNOWN
Conditions: Human Papillomavirus
Interventions: BIOLOGICAL: HPV 16/18 vaccine, 0,5ml|BIOLOGICAL: Placebo control, 0.5ml|BIOLOGICAL: HPV 16/18 vaccine, 1.0ml|BIOLOGICAL: Placebo control, 1.0ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effectiveness Of DN and STM Combined With Self-Stretching for Management of Calf and Heel Pain
Status: NOT_YET_RECRUITING
Conditions: Heel Pain Syndrome
Interventions: DIAGNOSTIC_TEST: Dry Needling|DIAGNOSTIC_TEST: Self Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bacteriophage Therapy in Spinal Cord Injury Patients With Bacteriuria
Status: NOT_YET_RECRUITING
Conditions: Bacteriuria|Spinal Cord Injuries|Asymptomatic Bacteriuria|Escherichia Coli
Interventions: DRUG: Phage Therapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Afatinib in Subjects With Kidney Dysfunction
Status: COMPLETED
Conditions: Renal Insufficiency
Interventions: DRUG: Afatinib healthy|DRUG: Afatinib severe renally impaired|DRUG: Afatinib moderate renally impaired
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Definition Versus Chromoendoscopy for Dysplasia Detection in Ulcerative Colitis (UC)
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: OTHER: High definition (HD) endoscopy|OTHER: chromoendoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, PK, PD, and Clinical Activity of EQ001 in Subjects With aGVHD
Status: COMPLETED
Conditions: Acute-graft-versus-host Disease|aGVHD|GVHD|GVHD, Acute
Interventions: BIOLOGICAL: EQ001|BIOLOGICAL: EQ001 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcriptional and Epimetabolic Profile of Breast Carcinoma With Luminal or HER2+ or Locally Advanced Triple-negative Histotype in Patients With/Without Previous Clinical History of Metabolic Syndrome
Status: RECRUITING
Conditions: Breast Cancer|Metabolic Syndrome
Interventions: PROCEDURE: Influence of metabolic syndrome on the achievement of pathological complete response
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Low FODMAP Diet on Colonic Epithelial Physiology in Diarrhea-predominant Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: a low FODMAP diet for 4 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate Overall Health, Physical Activity, and Joint Outcomes in Participants With Severe or Moderate Hemophilia A Without Factor VIII Inhibitors on Emicizumab Prophylaxis
Status: ACTIVE_NOT_RECRUITING
Conditions: Severe Hemophilia A|Moderate Hemophilia A
Interventions: DRUG: Emicizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Caudal Block Versus Dexmedetomidine Infusion in Pediatric Patients Undergoing Hypospadias Repair Surgery
Status: COMPLETED
Conditions: Dexmedetomidine Infusion|Pediatric|Hypospadias Repair Surgery
Interventions: DRUG: Dexmedetomidine|PROCEDURE: caudal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Fractional Doses of Pneumococcal Conjugate Vaccines on Immunogenicity and Carriage in Kenyan Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Pneumococcal Infection|Streptococcus Pneumoniae Infection|Invasive Pneumococcal Disease, Protection Against
Interventions: BIOLOGICAL: PCV10|BIOLOGICAL: PCV13
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of Percutaneous Implantation of the Medtronic CoreValve Aortic Valve Prosthesis (18Fr-Study)
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: Medtronic CoreValve System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daratumumab, Carfilzomib, Pomalidomide, Dexamethasone In MM
Status: RECRUITING
Conditions: Multiple Myeloma|Refractory Multiple Myeloma|Multiple Myeloma in Relapse|Relapse
Interventions: DRUG: Daratumumab|DRUG: Carfilzomib|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Quality of Life in Patients With AIDS-Associated Kaposi Sarcoma Treated With Bleomycin and Vincristine
Status: COMPLETED
Conditions: AIDS-Related Kaposi Sarcoma|Human Immunodeficiency Virus 1 Positive
Interventions: BIOLOGICAL: Bleomycin Sulfate|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Vincristine Sulfate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Leak-free Bronchoscope Adapter
Status: WITHDRAWN
Conditions: Respiratory Insufficiency
Interventions: DEVICE: Leak-free Bronchoscope Adapter|DEVICE: Standard Bronchoscope Adapter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: NSAIDs Versus Paracetamol Versus Paracetamol + NSAIDs in Traumatic Pain Management
Status: COMPLETED
Conditions: Acute Pain Due to Trauma
Interventions: DRUG: Paracetamol|DRUG: NSAID|DRUG: paracetamol-NSAID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of Machine Learning Based Personalized Nutrition Algorithm to Reduce Postprandial Glycemic Excursions Among North American Individuals With Newly Diagnosed Type 2 Diabetes
Status: TERMINATED
Conditions: Type2 Diabetes
Interventions: DEVICE: Abbott Freestyle Libre Pro|BEHAVIORAL: LifeStyle
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Escalation Study of GSK2838232 in Healthy Subjects
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: GSK2838232|DRUG: Placebo|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-Escalating Study of RO4987655 in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: RO4987655|DRUG: RO4987655
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibuprofen With or Without Acetaminophen for Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Acetaminophen|DRUG: Ibuprofen 600 mg|BEHAVIORAL: Educational intervention|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Non Invasive Ventilation on Lung Volumes Determined by Electrical Impedance Tomography
Status: UNKNOWN
Conditions: - Critical Care|Non Invasive Ventilation|Electrical Impedance Tomography|End Expiratory Lung Volume|End Expiratory Lung Impedance
Interventions: OTHER: non invasive ventilation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase Ib Study of APG-115 Single Agent or in Combination With Azacitidine or Cytarabine in Patients With AML and MDS.
Status: RECRUITING
Conditions: Acute Myeloid Leukemia (AML)|Myelodysplastic Syndromes (MDS)
Interventions: DRUG: APG-115|DRUG: Azacitidine|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of Platelet-rich Plasma Therapy in the Treatment of Androgenic Alopecia
Status: NOT_YET_RECRUITING
Conditions: Androgenic Alopecia
Interventions: BIOLOGICAL: Platelet-rich Plasma Left Side|BIOLOGICAL: Platelet-rich Plasma Right Side
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Propofol Patient-controlled Sedation for Endoscopic Retrograde Cholangiopancreatography
Status: COMPLETED
Conditions: Endoscopic Retrograde Cholangiopancreatography
Interventions: DRUG: Propofol sedation by nurse anaesthestist|DRUG: Patient-controlled propofol sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safe Threshold to Discontinue Phototherapy in Hemolytic Disease of Newborn
Status: UNKNOWN
Conditions: Hemolytic Disease of Newborn|Neonatal Hyperbilirubinemia
Interventions: DEVICE: phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Phrenic Nerve Blockade on Acute and Chronic Shoulder Pain in Patients for Lobectomy and Pneumonectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Phrenic nerve block with Ropivacaine|DRUG: Phrenic nerve block with saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BI 1744 CL in Patients With Severe Renal Impairment in Comparison to Subjects With Normal Renal Function
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1774 CL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Intra-articular SEMICAL GEL-B CROSS Therapy in Knee Osteoarthritis (SEM-ART1)
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Cross-linked intra-articular hyaluronic acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pragmatic Trial With Optimized Dose of Rifampicin and Moxifloxacin for the Treatment of Drug Susceptible Pulmonary Tuberculosis
Status: RECRUITING
Conditions: Tuberculosis|Human Immunodeficiency Virus
Interventions: DRUG: Optimised rifamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DNA Analysis From Isolated Cardiomyocytes in the Molecular Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia
Status: COMPLETED
Conditions: Arrhythmogenic Right Ventricular Dysplasia|Arrhythmogenic Right Ventricular Cardiomyopathy
Interventions: DIAGNOSTIC_TEST: Cardiomyocytes collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study on a Digital Platform for COVID19+ Patients, Designed to Facilitate Communication and Mental-health Care During and After Hospitalization.
Status: UNKNOWN
Conditions: COVID-19|Mental Health Impairment|Telemedicine
Interventions: OTHER: Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Vildagliptin Compared to Rosiglitazone in Drug Naive Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Reliability and Validity of the NCS (NCS-R)-Chinese Version
Status: COMPLETED
Conditions: Minimally Conscious State|Vegetative State
Interventions: DIAGNOSTIC_TEST: Nociception Coma Scale (NCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: First in Human Study of the DaVingi™ TR System in the Treatment of Patients With Functional Tricuspid Regurgitation
Status: UNKNOWN
Conditions: Functional Tricuspid Regurgitation (TR)
Interventions: DEVICE: DaVingiTR System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Comparison of Straumann Bone Ceramic and Bio-Oss With Guided Tissue Regeneration for Alveolar Ridge Preservation
Status: COMPLETED
Conditions: Bone Loss
Interventions: DEVICE: Straumann Bone Ceramic|DEVICE: Bio-Oss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Lung Recruitment Maneuvers for Postoperative Pediatric Atelectasis
Status: COMPLETED
Conditions: Atelectasis|Postoperative Complications|Recruitment|Pediatric|Abdominal Surgery
Interventions: PROCEDURE: conventional recruitment maneuvers|PROCEDURE: ultrasound-guided recruitment maneuvers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Database Retrieval for the Comprehensive Shoulder
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis of the Shoulder|Avascular Necrosis|Rheumatoid Arthritis|Prior Failed Revision|Correction of Functional Deformity|Fracture of Proximal End of Humerus|Cuff Tear Arthropathy
Interventions: DEVICE: Biomet Comprehensive Shoulder System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Risky Sex Prevention Intervention for Middle School Age Minority Girls
Status: COMPLETED
Conditions: HIV|Risky Sex Prevention
Interventions: BEHAVIORAL: Education, activities, empowerment, racial pride building|BEHAVIORAL: General Health education, activities
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: GRAVITAS: Gauging Responsiveness With A VerifyNow Assay-Impact On Thrombosis And Safety
Status: COMPLETED
Conditions: Coronary Arteriosclerosis|Acute Coronary Syndrome
Interventions: DRUG: clopidogrel|DRUG: placebo|DRUG: clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: The Effect of Melatonin on Gene Expression and Activity of the Sirt1 and Its Target Genes Catalase and MnSOD in Multiple Sclerosis Patients and Healthy Subjects
Status: COMPLETED
Conditions: Multiple Sclerosis|Oxidative Stress
Interventions: DRUG: Melatonin|OTHER: Hydrogen peroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Role Of Dexamethasone In Induction Of Labor
Status: UNKNOWN
Conditions: Dexamethasone Effect on Induction of Labor
Interventions: DRUG: Dexamethasone Sodium Phosphate|OTHER: Distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Radiation Therapy in Treating Patients With Stage III or Stage IV Larynx or Oropharynx Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xenotransplantation of Primary Cancer Samples in Zebrafish Embryos
Status: UNKNOWN
Conditions: Liver Cancer|Pancreatic Cancer|Gastric Cancer|Esophageal Cancer|Colo-rectal Cancer|Gall Bladder Cancer|Biliary Tract Cancer
Interventions: DRUG: Fluorouracil|DRUG: Lederfolin|DRUG: Oxaliplatin|DRUG: Irinotecan|DRUG: Docetaxel|DRUG: Cisplatin|DRUG: Epirubicin|DRUG: Gemcitabine|DRUG: Nab paclitaxel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Kinesio Taping Versus Interferential Current Therapy in Treating Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DEVICE: interferential current|OTHER: kinesio taping|OTHER: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azacitidine Maintenance Therapy After Allogeneic Bone Marrow Transplantation (Allo BMT)
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Leukemia
Interventions: DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Liposomal Bupivacaine Using Periarticular Injection in Total Knee Arthroplasty
Status: RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: DRUG: liposomal bupivacaine|DRUG: traditional peri-articular injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tumor Markers in Lung Cancer: DCAMLK-1LK-1
Status: COMPLETED
Conditions: Lung Cancer|Smoking
Interventions: OTHER: Measure DCAM levels in blood|OTHER: DCAM levels in blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy and Safety of AChE Inhibitor Donepezil As Adjunctive Treatment to Mood Stabilizers in Acute Mania
Status: COMPLETED
Conditions: Bipolar Disorder|Mania
Interventions: DRUG: Donepezil and Lithium|DRUG: Placebo plus Lithium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Association of Cathelicidin and Vitamin D Levels With the Category and Course of COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Chronic Obstructive Pulmonary Disease Moderate|Chronic Obstructive Pulmonary Disease Severe
Interventions: DRUG: Cholecalciferol Liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Pregabalin on Chronic Cough
Status: UNKNOWN
Conditions: Cough
Interventions: DRUG: Pregabalin|DRUG: Control-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Neuroprotection by Propofol and Desflurane for POCD Following Subarachnoid Hemorrhage Surgery
Status: COMPLETED
Conditions: Postoperative Cognitive Function
Interventions: DRUG: Propofol|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of a Group Psychological Intervention in Reducing Self-stigma Among Patients With Mental Disorders
Status: TERMINATED
Conditions: Self-stigma|Self Efficacy|Quality of Life
Interventions: BEHAVIORAL: Group psychological Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Intraocular Pressure (IOP)-Lowering Efficacy and Safety of AZORGA® Ophthalmic Suspension and COSOPT® Ophthalmic Solution
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Brinzolamide 1%/Timolol maleate 0.5% fixed combination ophthalmic suspension|DRUG: Dorzolamide hydrochloride 1%/Timolol maleate 0.5% ophthalmic solution|DRUG: Subject's habitual PGA monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Donor Lymphocyte Infusion in Treating Patients With Recurrent or Persistent Hematologic Cancer After Donor Stem Cell Transplant
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: donor lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caregiver Support Model & Psycho-Education Program On Empowerment: Development and Validation
Status: UNKNOWN
Conditions: Caregiver Burnout|Case Management|Empowerment
Interventions: BEHAVIORAL: Caregiver Support Model|BEHAVIORAL: Psycho-education Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Drains on Postoperative Nausea and Vomiting After Thyroid Surgery
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DEVICE: Placement of a wound drain post surgery (Redon; Medicoplast)|OTHER: No-drain after surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Seasonal Influenza DNA Vaccine Prime With Trivalent Inactivated Vaccine (TIV) Boost Compared to TIV Alone
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: DNA vaccine|BIOLOGICAL: TIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Investigate Pharmacokinetics (PK) of Pramipexole in Pediatric Patients Who Are Individually Optimized to Stable Pramipexole Doses for the Treatment of Idiopathic Restless Legs Syndrome (RLS)
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: MIRAPEX® - low|DRUG: MIRAPEX® - medium|DRUG: MIRAPEX® - high
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Video-guided Percutaneous Tracheostomy (PCT) Versus Conventional PCT: Comparing Safety and Efficacy
Status: UNKNOWN
Conditions: Bleeding|Hypoxia|Atelectasis|Pneumothorax|Pneumomediastinum
Interventions: DEVICE: Standard PCT|DEVICE: Video-guided PCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Safety, Efficacy, and Biomarker Response of BMS-986165 in Participants With Moderate to Severe Ulcerative Colitis
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: DRUG: BMS-986165|OTHER: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Clinical and Radiographical Evaluation of Treatment of Angular Bone Defect Related to Over Erupted Tooth Using GTR Followed by Orthodontic Intrusion Versus Orthodontic Intrusion Followed by GTR
Status: COMPLETED
Conditions: Bone Loss|Occlusion
Interventions: PROCEDURE: surgical (guided tissue regeneration)|DEVICE: orthodontic intrusion followed by guided tissue regeneration GTR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study With a New PDA Occluder for Closure of Patent Ductus Arteriosus
Status: COMPLETED
Conditions: Patent Ductus Arteriosus
Interventions: DEVICE: Occlutech PDA occluder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravascular Lithotripsy Versus Conventional Therapy for Severely Calcified Coronary Artery Lesions
Status: RECRUITING
Conditions: Severely Calcified Coronary Stenoses|De Novo Stenosis
Interventions: PROCEDURE: Intravascular Lithotripsy|PROCEDURE: Conventional lesion preparation strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nebulized Amikacin Versus Intravenous Amikacin in the Treatment of Nosocomial Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Nebulized Amikacin|DRUG: Intravenous Amikacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study to Assess Efficacy of Combined Treatment With Erlotinib (Tarceva) and Silybin-phytosome (Siliphos) in Patients With EGFR Mutant Lung Adenocarcinoma
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Erlotinib|DIETARY_SUPPLEMENT: Silybin-phytosome
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Level of PEEP in Protective One-lung Ventilation
Status: COMPLETED
Conditions: Video-assisted Thoracic Surgery|Postoperative Atelectasis|Positive End-expiratory Pressure
Interventions: PROCEDURE: PEEP 3 cm of water|PROCEDURE: PEEP 6 cm of water|PROCEDURE: PEEP 9 cm of water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mode of Induction in Fetal Growth Restriction and Its Affects on Fetal and Maternal Outcomes
Status: UNKNOWN
Conditions: Fetal Growth Retardation|Induction of Labor Affected Fetus / Newborn
Interventions: DRUG: prostaglandins E2|DEVICE: intracervical balloon catheter combined with pitocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ventral or Inguinal Hernia, Robotically Repaired With OviTex Mesh
Status: RECRUITING
Conditions: Hernia, Ventral|Hernia, Inguinal
Interventions: DEVICE: OviTex Reinforced Tissue Matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Quality of Recovery Between ESPB and IV Lidocaine After Major Breast Cancer Surgery
Status: NOT_YET_RECRUITING
Conditions: Breast Neoplasms
Interventions: DRUG: USG ESPB|DRUG: Intravenous Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Glycemic Load Diet in Patients With Stage I-III Colon Cancer
Status: COMPLETED
Conditions: Stage I Colon Cancer|Stage II Colon Cancer|Stage III Colon Cancer|Stage I Rectal Cancer|Stage II Rectal Cancer|Stage III Rectal Cancer
Interventions: OTHER: questionnaire administration|OTHER: laboratory biomarker analysis|BEHAVIORAL: Standard Dietary Intervention|BEHAVIORAL: Intensified Dietary Intervention|BEHAVIORAL: Low glycemic load|BEHAVIORAL: Medium Glycemic Load
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Real World Perspectives on Advancements in Hearing Aid Technology
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Phonak Audeo previous generation hearing aids|DEVICE: Phonak Audeo Lumity hearing aids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ambulatory SNP Under Local Anaesthesia in a Subgroup of Breast Cancer Patients - Trial
Status: UNKNOWN
Conditions: Breast Neoplasms
Interventions: PROCEDURE: Sentinel Node Procedure under Local Anaesthesia|PROCEDURE: Sentinel Node Procedure under General Anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Study Of Safety And Efficacy Of The SUPERA® Nitinol Stent - Iliac Artery
Status: WITHDRAWN
Conditions: With de Novo or Restenotic Lesions in the Common and/or External Iliac Arteries
Interventions: DEVICE: IDev SUPERA® Interwoven Self Expanding Nitinol Stent Peripheral Vascular System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of MiniGo as add-on to Oral Laxatives for Children With Constipation and Fecal Incontinence
Status: RECRUITING
Conditions: Functional Constipation|Fecal Incontinence in Children
Interventions: DRUG: Polyethylene Glycols|DEVICE: Low volume trans anal irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thermal Spread Into the Interstitial Portion of the Fallopian Tubes Using the Ligasure Device at Time of Hysterectomy
Status: COMPLETED
Conditions: Cervical Cancer|Ovarian Cancer|Uterine Cancer
Interventions: DEVICE: LigaSure vessel sealing system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MSCs Combined With CD25 Monoclonal Antibody and Calcineurin Inhibitors for Treatment of Steroid-resistant aGVHD
Status: UNKNOWN
Conditions: Acute Graft-versus-host Disease
Interventions: DRUG: CD25 monoclonal antibody|DRUG: calcineurin inhibitors|BIOLOGICAL: MSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Newborn Ventilation in the Delivery Room: Could it be Improved With a T-piece Resuscitator?
Status: COMPLETED
Conditions: Resuscitation
Interventions: DEVICE: T-piece resuscitator Neopuff TM|DEVICE: Self Inflating Bag with PEEP|DEVICE: Self Inflating Bag without PEEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT