pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Impact of Plant-based Blends on Skeletal Muscle Protein Synthesis Rates in Older Adults
Status: RECRUITING
Conditions: Nutrition, Healthy
Interventions: DIETARY_SUPPLEMENT: Milk protein ingestion|DIETARY_SUPPLEMENT: Cron protein ingestion|DIETARY_SUPPLEMENT: Corn+Pea protein ingestion|DIETARY_SUPPLEMENT: Non-protein, low energy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Pressure Threshold Values Versus the Biomechanical-Viscoelastic Findings of L4-5 Supraspinous Ligament in Women Who Underwent Cesarean Delivery With Spinal Anaesthesia
Status: COMPLETED
Conditions: Low Back Biomechanical Dysfunctions
Interventions: DEVICE: Pressure algometry (Baseline 2.2-Pound Dolorimeter) and Myoton PRO device (MyotonPRO; Myoton AS, Tallinn, Estonia)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess the Safety of Escalating Doses of AT13387 in Patients With Metastatic Solid Tumors
Status: COMPLETED
Conditions: Metastatic Solid Tumors
Interventions: DRUG: AT13387|DRUG: AT13387
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Dark Chocolate Implementation in Elite Athletes
Status: COMPLETED
Conditions: Oxidative Stress|Athletes Heart|Physical Activity
Interventions: DIETARY_SUPPLEMENT: Dark Chocolate (85% cocoa)|DIETARY_SUPPLEMENT: White/Milk chocolate (<35% cocoa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: XP13512 (GSK1838262) Versus Placebo in Patients With Restless Legs Syndrome.
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: XP13512 (GSK1838262)|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Racial Differences in Vagal Control of Glucose Homeostasis, Chronic Study
Status: WITHDRAWN
Conditions: Insulin Sensitivity|Oxidative Stress
Interventions: DRUG: Galantamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Taxotere (Docetaxel) in 1st Line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Head and Neck Neoplasms|Neoplasm Recurrence, Local|Neoplasm Metastasis
Interventions: DRUG: docetaxel (XRP6976)|DRUG: cisplatin|DRUG: 5-fluorouracil (5-FU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between One-stage Hybrid Ablation and Thoracoscopic Surgical Ablation for Intractable Atrial Fibrillation
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: Hybrid ablation|PROCEDURE: Thoracoscopic surgical ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Carotid Artery Stenosis and Abdominal Aortic Aneurysms in Brussels: a Population-based Screening Study.
Status: COMPLETED
Conditions: Carotid Artery Stenosis|Abdominal Aortic Aneurysm|Epidemiology
Interventions: DIAGNOSTIC_TEST: Duplex ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: EUS Evaluation of CBD Diameter in Malignant Obstructive Jaundice
Status: COMPLETED
Conditions: Pancreatic Cancer|Cholangiocarcinoma of the Extrahepatic Bile Duct|Ampulla of Vater Cancer|Jaundice, Obstructive
Interventions: DIAGNOSTIC_TEST: Endoscopic ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Supplementation With Anthocyanins on Iron Metabolism in Female Swimmers
Status: COMPLETED
Conditions: Iron Deficiencies|Inflammation|Oxidative Stress|Female Athlete Triad
Interventions: DRUG: Black chokeberry extract in capsules with 18% standardization of the anthocyanins content|DRUG: Chokeberry fiber in capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Corticosteroids to Reduce Frequency of Seizures in Neurocysticercosis Patients
Status: COMPLETED
Conditions: Neurocysticercosis
Interventions: DRUG: Albendazole|DRUG: Dexamethasone|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Imaging of Psychic Pain
Status: TERMINATED
Conditions: Suicide, Attempted|Mood Disorder
Interventions: BEHAVIORAL: Assessment of personality traits|BEHAVIORAL: Assessment of suicidal act|BEHAVIORAL: Assessment of depression|PROCEDURE: Cyber ball game|PROCEDURE: Iowa Gambling Task|PROCEDURE: Microcomputer|PROCEDURE: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Anterior Cruciate Ligament Reconstruction With a Periosteal - Patellar Tendon - Bone Autograft - The Kocabey Press-Fit Technique
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Rupture
Interventions: PROCEDURE: Anterior cruciate ligament (ACL) reconstruction with a periost-patellar-tendon-bone (PPTB) autograft and a tibial press-fit technique
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intravitreal Injections of Ziv-aflibercept for Macular Diseases
Status: COMPLETED
Conditions: Diabetic Macular Edema|Age Related Macular Degeneration|Branch Retinal Vein Occlusion With Macular Edema|Central Retinal Vein Occlusion With Macular Edema
Interventions: DRUG: Intravitreal injections of ziv-aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Effectiveness of Continuous Glucose Monitoring in Enhancing Surgical Outcomes for Diabetic Patients
Status: RECRUITING
Conditions: Comprehensive Complication Index
Interventions: DEVICE: Continuous glucose monitoring (CGM) device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Intervention With Neuromodulation and Inverse Virtual Reality in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DEVICE: The Exopulse Mollii Suit on a Fibromyalgia patient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Fluorometholone (FML) in Dry Eye Disease (Keratoconjunctivitis Sicca)
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: FML 0.1% eyedrops|DRUG: Liquifilm artificial tears eyedrops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Atropine in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
Status: COMPLETED
Conditions: Catecholaminergic Polymorphic Ventricular Tachycardia
Interventions: DRUG: Atropine|PROCEDURE: Exercise treadmill test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Awake Fiber Optic Intubation (AFOI) and Laryngeal Nervous Block
Status: UNKNOWN
Conditions: Airway Complication of Anesthesia
Interventions: DRUG: superior laryngeal nerve block with lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Ventilation in Moderate-to-severe COVID-19-associated Acute Respiratory Distress-syndrome
Status: COMPLETED
Conditions: Covid19|ARDS
Interventions: DIAGNOSTIC_TEST: Respiratory monitoring|DIAGNOSTIC_TEST: Respiratory muscles ultrasound|DIAGNOSTIC_TEST: Electro impedance tomography|DIAGNOSTIC_TEST: Capnography|DIAGNOSTIC_TEST: Arterial blood gas|DIAGNOSTIC_TEST: Quasistatic pressure-volume curve
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BMS-790052 (Daclatasvir) Plus Peg-Interferon Alfa-2a and Ribavirin in Treatment-Naive Black/African-Americans, Latinos and White/Caucasians With Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Daclatasvir|DRUG: Peg-Interferon Alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Pharmacokinetics, Pharmacodynamics, Food Effects, and Drug-drug Interactions of ACP-196 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: ACP-196|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Anti-Inflammatory Treatment in Dry Eye Patients
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: Difluprednate 0.05% ophthalmic emulsion|OTHER: Difluprednate vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Cookies Containing 2.5 g Spirulina on Postprandial Glycemic and Insulin Responses
Status: COMPLETED
Conditions: Potential Abnormality of Glucose Tolerance|Appetitive Behavior|Blood Pressure
Interventions: OTHER: Glucose as reference food|OTHER: White bread|DIAGNOSTIC_TEST: Cookie containing 0 g spirulina|OTHER: Cookie containing 2.5 g spirulina
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Surgical Repair of Vaginal Wall Prolapse Using Gamma Irradiated Amniotic Membrane as a Scaffold
Status: COMPLETED
Conditions: Vaginal Wall Prolapse
Interventions: PROCEDURE: Vaginal Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Asahi Intecc PTCA Chronic Total Occlusion Study
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Artery Chronic Total Occlusion
Interventions: DEVICE: Crossing of Coronary Artery CTO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Information and Breathing Technique - for Patients With Respiratory Pain in Acute Pulmonary Embolism.
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: OTHER: Information on anatomy and physiology, and breathing technique|OTHER: Usual care treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetic Foot Ulcer Study Comparing Cytal Wound Matrix 1-Layer to Standard of Care
Status: TERMINATED
Conditions: Diabetes|Diabetic Foot|Diabetes Mellitus, Type 2|Diabetes Mellitus, Type 1
Interventions: DEVICE: Cytal Wound Matrix 1-Layer|OTHER: Standard of Care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Dose Multivitamins Compared to a Placebo in Preventing the Recurrence of Cancer in Patients With Early Stage Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DIETARY_SUPPLEMENT: multivitamin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer
Status: RECRUITING
Conditions: Metastatic Castration-Resistant Prostate Cancer
Interventions: DRUG: ZEN003694|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Chinese Adult Subjects With DSM-5 Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: Xanomeline and Trospium Chloride Capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carotid Artery Disease After Stroke (CADAS).
Status: WITHDRAWN
Conditions: Carotid Artery Diseases|Stroke|Transient Ischemic Attack
Interventions: DIAGNOSTIC_TEST: 3 Dimensional tomographic Ultrasound|DIAGNOSTIC_TEST: Platelet Aggregometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Sprinkles With and w/o Fe on Zn Absorption in Kenyan Toddlers
Status: COMPLETED
Conditions: Micronutrient Deficiencies
Interventions: DIETARY_SUPPLEMENT: MNP + Zn/Fe|DIETARY_SUPPLEMENT: MNP + Zn|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acupuncture Therapy on Dysphagia in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Routine rehabilitation training|BEHAVIORAL: Swallowing rehabilitation training|PROCEDURE: Acupuncture therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Hyaluronan-enriched Medium on the Cumulative Ongoing Pregnancy Rate.
Status: RECRUITING
Conditions: Hyaluronan-EnRiched Medium|Randomized Controlled Trial
Interventions: OTHER: use of hyaluronan-enriched transfer medium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Exercise Capacity and Recovery in Addison's Disease
Status: UNKNOWN
Conditions: Addison's Disease
Interventions: OTHER: ergometry|OTHER: ergometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Partial Body Weight Support Play Environment to Encourage Mobility and Exploration in Infants With Down Syndrome
Status: COMPLETED
Conditions: Down Syndrome|Trisomy 21
Interventions: DEVICE: Enriched Play Environment with Partial Body Weight Support Harness|OTHER: Enriched Play Environment without Partial Body Weight Support Harness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: To Compare Fibrin Glue and Suture in Primary Pterygium Excision With Amniotic Membrane Transplantation
Status: COMPLETED
Conditions: Pterygium
Interventions: PROCEDURE: Amniotic membrane transplantation using fibrin glue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Modafinil in Methamphetamine Dependence
Status: COMPLETED
Conditions: Methamphetamine Dependence
Interventions: DRUG: Modafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Healing Touch and Relaxation Therapies in Cervical Cancer Patients
Status: COMPLETED
Conditions: Cervix Neoplasms
Interventions: BEHAVIORAL: Healing Touch Therapy|BEHAVIORAL: Relaxation Therapy|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ⅱ Study of Gemcitabine Combination With TS-1 in Patient With Advanced or Recurred Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Neoplasm|Neoplasm Metastasis
Interventions: DRUG: gemcitabine, TS-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamic Changes of Monocytes and NK Cells of CHC Patient Treated by DAAs
Status: COMPLETED
Conditions: Chronic Hepatitis C (Disorder)
Interventions: DRUG: Ledipasvir-Sofosbuvir|DRUG: Daclatasvir-Sofosbuvir
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Low Protein Formula on Renal Function, Oxidative Stress and Antioxidant Capacities in CKD Patients
Status: UNKNOWN
Conditions: Chronic Renal Disease
Interventions: DIETARY_SUPPLEMENT: Low protein formula group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immune Response Regulation and Nutritional Status of the Crohn's Disease Patients.
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DIETARY_SUPPLEMENT: Whey protein|DIETARY_SUPPLEMENT: Soy protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double-blind, Placebo-controlled Trial to Investigate Safety and Efficacy of Cerebrolysin™ in Patients With Aneurysmal Subarachnoid Hemorrhage
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage|Intracranial Aneurysm|Delayed Cerebral Ischemia|Delayed Ischemic Neurological Deficit
Interventions: DRUG: Intravenous Cerebrolysin|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Mixed Meal Challenge Study
Status: COMPLETED
Conditions: Cardiovascular Diseases|Hyperlipidemias
Interventions: DIETARY_SUPPLEMENT: Lipid Challenge|DIETARY_SUPPLEMENT: Glucose Challenge|DIETARY_SUPPLEMENT: Mixed Meal Challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prospective, Multi-Center All-Comer Biliary Canadian WallFlex Registry
Status: COMPLETED
Conditions: Biliary Strictures
Interventions: DEVICE: WallFlex™ Biliary RX Fully Covered Stent System RMV|DEVICE: WallFlex™ Biliary RX Partially Covered Stent System|DEVICE: WallFlex™ Biliary RX Uncovered Stent System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Instrument Assisted Soft Tissue Mobilization in Management of Piriformis Syndrome
Status: RECRUITING
Conditions: Piriformis Syndrome
Interventions: OTHER: Conventional treatment|OTHER: Instrument assisted soft tissue mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Routine Cardiac Screening in Sarcoidosis Patients
Status: RECRUITING
Conditions: Sarcoidosis|Cardiac Sarcoidosis|Boeck's Disease|Besnier-Boeck Disease
Interventions: DIAGNOSTIC_TEST: Enhanced Screening Protocol for Cardiac Sarcoidosis.|DIAGNOSTIC_TEST: Routine Screening for Suspected Cardiac Sarcoidosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Dexmedetomidine for Catheter-related Bladder Discomfort
Status: UNKNOWN
Conditions: Pain|Blood Pressure|Nausea|Vomiting|Arrhythmia
Interventions: DRUG: Dex infusion|DRUG: NS infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Mechanical Ventilation in the Emergency Department: A Prospective Cross-Sectional Study
Status: COMPLETED
Conditions: Respiratory Failure|Mechanical Ventilation|Acute Lung Injury
Interventions: OTHER: For inclusion in the study, patients will have to require mechanical ventilation either via an endotracheal tube or tracheostomy tube.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: DepoCyt Therapy in Patients With Neoplastic Meningitis From Lymphoma or a Solid Tumor
Status: COMPLETED
Conditions: Meningeal Neoplasms
Interventions: DRUG: Intrathecal (injected into the spinal fluid) DepoCyt|DRUG: Intrathecal methotrexate|DRUG: Intrathecal cytarabine (also known as ara-C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Performing a Motor Imagery Task on Cortical Excitability During Acute Experimental Muscle Pain and Acute Itch
Status: NOT_YET_RECRUITING
Conditions: Itch|Pain
Interventions: OTHER: Hypertonic Saline|OTHER: Histamine|OTHER: Cowhage|DEVICE: Transcranial magnetic stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase Ib/II of TG4001 and Avelumab in HPV16 Positive R/M Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: HPV-Related Carcinoma|HPV-Related Cervical Carcinoma|HPV-Related Anal Squamous Cell Carcinoma|HPV-Related Penile Squamous Cell Carcinoma|HPV-Related Vulvar Squamous Cell Carcinoma
Interventions: BIOLOGICAL: TG4001|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Registry Of Acute meDical Emergencies in Brazil
Status: UNKNOWN
Conditions: Acute Coronary Syndromes|Heart Failure|Pulmonary Edema|Aortic Aneurysm, Familial Thoracic 1|Chest Pain|Pulmonary Embolism|Syncope
Interventions: OTHER: no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Autologous Platelet-Rich Plasma (PRP) and Endometrial Thickness
Status: UNKNOWN
Conditions: Thin Endometrium|Endometrial Disorder|Endometrial Thickness Not Growing Under Estrogen Stimulation
Interventions: DRUG: PRP|DEVICE: Tomcat catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Sub-Clinical Bacteriuria in Pregnancy
Status: COMPLETED
Conditions: Cystitis|Cystitis;Puerperium|Pyelonephritis
Interventions: DRUG: Antibiotic|OTHER: Standard Prenatal Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluvastatin 80 mg Ret. vs Combination With Ezetimibe 10 mg in Patients With High Cardiovascular Risk
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: fluvastatin|DRUG: Fluvastatin plus ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Application of Simulated Training in Ultrasound Guided Transversus Abdominis Plane Block
Status: UNKNOWN
Conditions: Transversus Abdominis Plane Block|Simulation Training|Learning Curve
Interventions: OTHER: simulated puncture training|OTHER: traditional bedside teaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Preventing Childbirth-Related PTSD With Expressive Writing
Status: RECRUITING
Conditions: PTSD (Childbirth-Related)
Interventions: BEHAVIORAL: Expressive Writing about Childbirth|BEHAVIORAL: Neutral Writing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Selinexor in Combination With Ixazomib for the Treatment of Advanced Sarcoma
Status: WITHDRAWN
Conditions: Liposarcoma|Malignant Peripheral Nerve Sheath Tumors|Alveolar Soft Part Sarcoma|Ewing Sarcoma|Sarcoma
Interventions: DRUG: Selinexor|DRUG: Ixazomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Intrabony Defects With Simvastatin and Antimicrobial Photodynamic Therapy
Status: RECRUITING
Conditions: Simvastatin|Photodynamic Therapy|Periodontal Diseases
Interventions: PROCEDURE: SMV and antimicrobial photodynamic therapy|PROCEDURE: SMV application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Reduction in Erythema in Adult Patients With Moderate to Severe Persistent Facial Erythema Associated With Rosacea
Status: COMPLETED
Conditions: Rosacea|Erythema
Interventions: DRUG: Oxymetazoline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scale Down for Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Cancer|Cancer of the Endometrium
Interventions: BEHAVIORAL: ScaleDown|BEHAVIORAL: Enhanced Usual Care Packets|OTHER: 12-Item Short Form Health Survey|OTHER: International Physical Activity Questionnaire short form|OTHER: Multidimensional Body Self Relations Questionnaire - Appearance Subscales|OTHER: Cancer-Related Body Image Scale|OTHER: Patient Health Questionnaire 9-Item Version|BEHAVIORAL: iOTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimizing the Use of Ketamine to Reduce Chronic Postsurgical Pain
Status: RECRUITING
Conditions: Chronic Postsurgical Pain
Interventions: DRUG: Continuous ketamine infusion|DRUG: Ketamine + Saline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Tirzepatide (LY3298176) Versus Insulin Lispro (U100) in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine (U100) With or Without Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Tirzepatide|DRUG: Insulin Lispro (U100)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and Capecitabine in Patients With Metastatic/Recurrence Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: DRUG: Paclitaxel|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TH9507 Extension Study in Patients With HIV-Associated Lipodystrophy
Status: COMPLETED
Conditions: Lipodystrophy|HIV Infections
Interventions: DRUG: Tesamorelin|DRUG: Placebo for Tesamorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Speech Competition Training on Auditory Hallucination in Schizophrenia
Status: RECRUITING
Conditions: Auditory Hallucination
Interventions: OTHER: speech competition training|OTHER: the soothing music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Glycemic Index in 4 Dairy Beverages.
Status: COMPLETED
Conditions: Glycemic Index|Cognitive Performance
Interventions: OTHER: Experimental product|OTHER: Control product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Extension Study to Determine the Efficacy and Safety of STI571 in Participants With Chronic Myeloid Leukemia Who Are Refractory to or Intolerant of Interferon-Alpha
Status: COMPLETED
Conditions: Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Interventions: DRUG: STI571
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity/Safety of Measles-Mumps-Rubella-Varicella Vaccine (MeMuRu-OKA): Using Two Different Administration Routes
Status: COMPLETED
Conditions: Measles|Mumps|Rubella|Varicella
Interventions: BIOLOGICAL: MeMuRu-OKA (study vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Edge-to-edge Mitral Valve Repair in ATTR-CM
Status: NOT_YET_RECRUITING
Conditions: Mitral Regurgitation|ATTR-Cardiomyopathy|Edge-to-Edge Mitral Valve Repair
Interventions: DEVICE: TEER|OTHER: Optimal Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A QT/QTc Evaluation Study of TS-142 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: TS-142|DRUG: Moxifloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of Fusilev to Prevent or Reduce Mucositis in Patients With Non-Hodgkin's Lymphoma Receiving Folotyn
Status: WITHDRAWN
Conditions: Non Hodgkin's Lymphoma
Interventions: DRUG: Fusilev|DRUG: Folotyn
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Modified Citrus Pectin on PSA Kinetics in Biochemical Relapsed PC With Serial Increases in PSA
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DIETARY_SUPPLEMENT: PectaSol-C Modified Citrus Pectin (MCP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eye Movement Desensitization and Reprocessing (EMDR) as a Treatment of Substance Use Disorders
Status: UNKNOWN
Conditions: Psychotherapy|Substance Use Disorders
Interventions: OTHER: EMDR-Therapy|OTHER: Sham Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pediatric Septic Shock Treatment With and Without Central Venous Oxygen Saturation Monitoring
Status: COMPLETED
Conditions: Severe Sepsis|Septic Shock
Interventions: PROCEDURE: Central venous oxygen saturation continuous monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Perioperative Ketamine on Acute and Chronic Pain After Major Back Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Placebo|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies
Status: RECRUITING
Conditions: Hematologic Neoplasms
Interventions: PROCEDURE: donor lymphocyte infusion|DRUG: Cyclophosphamide|DRUG: Busulfan|DRUG: Mycophenolate mofetil|DRUG: Fludarabine|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effectiveness, Safety, and Tolerability of Carisbamate as Add-On Therapy in Patients With Partial Onset Seizures.
Status: COMPLETED
Conditions: Epilepsy, Partial, Motor|Epilepsy, Complex Partial|Epilepsy, Simple Partial|Focal Motor Epilepsy
Interventions: DRUG: Carisbamate|DRUG: placebo|DRUG: Carisbamate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional MRI-based Assessment of Terlipressin vs. Octreotide on Renal Function in Cirrhotic Patients With Acute Variceal Bleeding (CHESS1903)
Status: UNKNOWN
Conditions: Renal Function Disorder|Acute Variceal Bleeding
Interventions: DRUG: Terlipressin|DRUG: Octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Ziv-aflibercept Efficacy in Better Regulating AMD
Status: COMPLETED
Conditions: Wet Macular Degeneration|Wet Age-related Macular Degeneration
Interventions: DRUG: Ziv-Aflibercept 25 MG/ML [Zaltrap]|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Will Erwin Headache Research Center - Cluster Headache Study
Status: RECRUITING
Conditions: Cluster Headache|Cluster Headaches and Other Trigeminal Autonomic Cephalgias|Paroxysmal Hemicrania|SUNCT|Hemicrania Continua|Trigeminal Neuralgia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Erlotinib in Treating Patients With Locally Advanced or Metastatic Stomach Cancer or Gastroesophageal Junction Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: erlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety, Tolerability and PK of HF1K16 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HF1K16|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Capsaicin and Cinnamaldehyde on Intestinal Permeability
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Capsaicin|DIETARY_SUPPLEMENT: Cinnamaldehyde|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Wound Healing Effects of HO/03/03 In Patients With Diabetic Neuropathic Plantar and Venous Ulcers, Pilot Study.
Status: COMPLETED
Conditions: Diabetic Foot Ulcer|Venous Ulcer
Interventions: DRUG: HO/03/03
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of a Vacuum Mattress During Laparoscopic Sleeve Gastrectomy to Reduce the Concentration of Rhabdomyolysis Markers and Acute Renal Failure
Status: COMPLETED
Conditions: Rhabdomyolysis|Acute Kidney Injury|Bariatric Surgery Candidate
Interventions: DEVICE: vacuum mattress|OTHER: Standard Mattress
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Chronic Pain After Video-assisted Thoracoscopic Surgery (VATS) Surgery for Pneumothorax
Status: TERMINATED
Conditions: Pneumothorax
Interventions: DEVICE: 5mm videoscope|DEVICE: 10mm videoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Testing the Addition of a New Anti-cancer Drug, Radium-223 Dichloride, to the Usual Treatment (Cabozantinib) for Advanced Renal Cell Cancer That Has Spread to the Bone, RadiCaL Study
Status: RECRUITING
Conditions: Advanced Renal Cell Carcinoma|Chromophobe Renal Cell Carcinoma|Clear Cell Renal Cell Carcinoma|Collecting Duct Carcinoma|Kidney Medullary Carcinoma|Metastatic Malignant Neoplasm in the Bone|Papillary Renal Cell Carcinoma|Stage IV Renal Cell Cancer AJCC v8|Unclassified Renal Cell Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|DRUG: Cabozantinib S-malate|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Radium Ra 223 Dichloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concurrent fMRI-guided rTMS and Cognitive Therapy for the Treatment of Major Depressive Episodes
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: Sham TMS + Cognitive therapy|DEVICE: Active TMS + Cognitive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Using Azithromycin Versus Placebo With Dexamethasone in Prevention of Post-spinal Nausea and Vomiting.
Status: UNKNOWN
Conditions: Post-operative Nausea and Vomiting
Interventions: DRUG: Oral Azithromycin tablet|DRUG: Intravenous dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Mesenchymal Stem Cells Transplantation for Systemic Sclerosis (SSc)
Status: UNKNOWN
Conditions: Systemic Sclerosis|Mesenchymal Stem Cells
Interventions: BIOLOGICAL: Allogeneic Mesenchymal Stem Cells (AlloMSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Neoadjuvant SAR444245 Plus Cemiplimab in HPV Related Oropharynx Squamous Cell Carcinoma
Status: WITHDRAWN
Conditions: Squamous Cell Carcinoma|Oropharynx Cancer|Head and Neck Cancer
Interventions: DRUG: SAR444245|DRUG: Cemiplimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics (PK) of Gantenerumab Following Subcutaneous (SC) Administration in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Gantenerumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of RGMA001 on Patients With Non Alcoholic Fatty Liver Disease (NAFLD)
Status: UNKNOWN
Conditions: Non Alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: RGMA001|DIETARY_SUPPLEMENT: Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Project FACTS (Fidelity Accuracy: Comparing Three Strategies)
Status: COMPLETED
Conditions: Assess Fidelity to Cognitive-behavioral Therapy for Youth
Interventions: BEHAVIORAL: Self-report|BEHAVIORAL: Chart-Stimulated Recall|BEHAVIORAL: Behavioral Rehearsal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Targeted Therapy With Lapatinib in Patients With Recurrent Pituitary Tumors Resistant to Standard Therapy
Status: COMPLETED
Conditions: Pituitary Adenomas|Prolactinomas
Interventions: DRUG: Lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Use of Plastic Bags in Preventing and Treating Hypothermia in Neonates
Status: COMPLETED
Conditions: Hypothermia, Newborn
Interventions: PROCEDURE: Resuscitation and post resuscitation care with plastic bag|PROCEDURE: Resuscitation- no plastic bag for temperature regulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Cell Therapy for Subjects With Acute Kidney Injury Who Are Receiving Continuous Renal Replacement Therapy
Status: UNKNOWN
Conditions: Acute Kidney Injury
Interventions: BIOLOGICAL: SBI-101|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Intensity Interval Versus Continuous Moderate Intensity Training: Maximizing the Benefits of Exercise in Overweight Adolescents
Status: COMPLETED
Conditions: Metabolism|Physical Fitness
Interventions: OTHER: High Intensity Interval Training|OTHER: Moderate Intensity Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Effectiveness and Safety Study With RWJ-333369 (Carisbamate) for the Study of Postherpetic Neuralgia (PHN).
Status: COMPLETED
Conditions: Postherpetic Neuralgia|Neuralgia|Herpes Zoster
Interventions: DRUG: placebo|DRUG: carisbamate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Blood Glucose Changes in Healthy Volunteers After BMS-754807 Alone or BMS-754807 With Metformin
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BMS-754807 (IGR-IR/IR Inhibitor)|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Genetic Testing and Counseling to Reduce Diabetic Complications
Status: COMPLETED
Conditions: Diabetic Complication
Interventions: BEHAVIORAL: Personalized Risk Counselling|OTHER: Normal usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study Evaluating FT-SW in Unilateral Breast Cancer-Related Lymphedema Patients
Status: TERMINATED
Conditions: Breast Cancer Related Lymphedema
Interventions: DEVICE: Flexitouch Plus|DEVICE: Flexitouch Plus FT with software modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Adult Patients With Schizophrenia (EMERGENT-3)
Status: COMPLETED
Conditions: Schizophrenia|Schizophrenia; Psychosis
Interventions: DRUG: Xanomeline and Trospium Chloride Capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Dexmedetomidine in Elderly Under General Anesthesia
Status: COMPLETED
Conditions: Hip Fractures|Hip Disease
Interventions: DRUG: Dexmedetomidine|DRUG: Normal saline|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sevoflurane and Propofol for Botulinum Toxin Injection
Status: WITHDRAWN
Conditions: Cerebral Palsy
Interventions: DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Safety and Pharmacokinetics of HUG116 Tablet and Viread® Tablet in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Viread® tablet 300mg|DRUG: HUG116 tablet 245mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Memory & Conditioning Under Anesthesia
Status: COMPLETED
Conditions: Anesthesia|Pain
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol|DRUG: Fentanyl|DEVICE: Peripheral Nerve Stimulation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect Of Dry Needling On Quality Of Life In Patients With Trigger Fingers
Status: COMPLETED
Conditions: Trigger Finger Disorder
Interventions: PROCEDURE: Dry needling|OTHER: conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Group B Streptococcus Vaccine in Healthy Women
Status: COMPLETED
Conditions: Group B Streptococcus
Interventions: BIOLOGICAL: Group B streptococcus (GBS) vaccine- low dose|BIOLOGICAL: Group B streptococcus (GBS) vaccine- High dose|BIOLOGICAL: Placebo- Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Raltegravir and Atazanavir Dosing Strategy Study
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: atazanavir plus raltegravir|DRUG: atazanavir plus raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)
Status: TERMINATED
Conditions: Cutaneous Lupus Erythematosus
Interventions: DRUG: Edecesertib|DRUG: Placebo|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Gentian Violet (GV) Mouth Washes, Nystatin, and Ketoconazole Tabs in Treating Oropharyngeal Candidiasis
Status: COMPLETED
Conditions: Candidiasis, Oral
Interventions: DRUG: Gentian violet 1% solution|DRUG: Gentian violet 0.00165% solution|DRUG: Nystatin solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Gadolinium Contrast-enhanced Abbreviated MRI (AMRI) vs. Standard Ultrasound for Hepatocellular Carcinoma (HCC) Surveillance in Patients With Cirrhosis
Status: RECRUITING
Conditions: Liver Cancer|Liver Cirrhoses|Liver Carcinoma
Interventions: DRUG: Gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING