pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy of Oral Tofacitinib in Moderate to Severe Alopecia Areata, Totalis and Universalis at Tertiary Care Hospital, Karachi.
Status: COMPLETED
Conditions: Alopecia Areata|Alopecia Totalis|Alopecia Universalis
Interventions: DRUG: Tofacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CellCept (Mycophenolate Mofetil) in Combination Therapy in Liver Transplant Patients.
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DRUG: Mycophenolate mofetil, adjusted dose|DRUG: Tacrolimus|DRUG: Corticosteroids, IV|DRUG: Mycophenolate mofetil, Standard dose|DRUG: Corticosteroids, PO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Suctioning by Bronchoscope on Postoperative Pulmonary Complications Among Patients With SCI in the PACU
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: BEHAVIORAL: suction with bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of MCCE With/Without Tether vs Conventional Upper Endoscopy in Patients With Upper Abdominal Symptoms
Status: COMPLETED
Conditions: Upper Gastrointestinal Symptoms
Interventions: DEVICE: MCC/MCC-T|DEVICE: Standard gastroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bioavailability and Bioactivity of Red Wine Melatonin in Humans
Status: COMPLETED
Conditions: Bioavailability
Interventions: OTHER: Red wine with melatonin|OTHER: Red wine without melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: MRI for the Early Evaluation of Acute Intracerebral Hemorrhage
Status: COMPLETED
Conditions: Cerebral Hemorrhage|Intracranial Arteriovenous Malformations|Intracranial Hemorrhage, Hypertensive|Brain Neoplasms
Interventions: DEVICE: MRI Scan with the specified sequences below:
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Personalized Feedback Intervention for Latinx Drinkers With Anxiety
Status: RECRUITING
Conditions: Alcohol Abuse|Anxiety
Interventions: BEHAVIORAL: Alcohol-Anxiety Personalized Feedback Intervention 2.0|BEHAVIORAL: Control Personalized Feedback Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Placebos to Treat Fatigue in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Fatigue
Interventions: OTHER: OLP treatment|OTHER: Usual care|OTHER: Expectancy Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Urine Levels of Metanephrin and Normetanephrin in Patients With Frequent Ventricular Premature Complex
Status: COMPLETED
Conditions: Premature Ventricular Contraction
Interventions: DIAGNOSTIC_TEST: 24 hours urine levels metanephrine and normetanephrine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Ursodeoxycholic Acid on Graft Recovery Early After Adult Liver Transplantation
Status: COMPLETED
Conditions: Liver Transplantation|Ischemia-reperfusion Injury|Cholestasis
Interventions: DRUG: ursodeoxycholic acid|DRUG: identical-appearing placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Isolated Vascularized Gastric Tube Biliary Enteric Drainage: A Paediatric Case Series Experience.
Status: COMPLETED
Conditions: Biliary Obstruction|Choledochal Cyst
Interventions: PROCEDURE: Isolated Vascularized Gastric Tube (IVGT) graft
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Continuous Soluble Ferric Pyrophosphate (SFP) Iron Delivery Via Dialysate in Hemodialysis Patients
Status: COMPLETED
Conditions: Renal Failure Chronic Requiring Hemodialysis
Interventions: DRUG: Soluble Ferric Pyrophosphate (SFP)|DEVICE: Standard dialysate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Predictive Factors of Pelvic Magnetic Resonance in the Response of Arterial Embolization of Uterine Leiomyoma
Status: COMPLETED
Conditions: Exposure to Magnetic Field|Uterine Leiomyoma
Interventions: PROCEDURE: Magnetic Resonance Image
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PK and Safety in Participants Taking Obicetrapib With Moderate Hepatic Impairment Relative to Normal Hepatic Function
Status: RECRUITING
Conditions: Hepatic Impairment|Healthy
Interventions: DRUG: Obicetrapib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of "Autogenous Leukocyte Platelet Rich Fibrin- Tooth Graft" Combination Around Immediately Placed Implants
Status: COMPLETED
Conditions: Autogenous Tooth Bone Graft|Immediate Implant Placement|L-PRF
Interventions: COMBINATION_PRODUCT: immediate implant placement with ATBG and L-PRF|COMBINATION_PRODUCT: immediate implant placement with ATBG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Comparative, Double-blind Trial of Pentaisomaltose and Dimethyl Sulphoxide for Cryoprotection of Hematopoietic Stem Cells in Subjects With Multiple Myeloma or Malignant Lymphoma With a Need for Autologous Transplantation
Status: NOT_YET_RECRUITING
Conditions: Malignant Lymphoma|Multiple Myeloma
Interventions: OTHER: Pentaisomaltose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Tidal Volume on Oxygenation, Respiratory Mechanics, and Pulmonary Complications in Older Patients Undergoing Trendelenburg Pneumoperitoneum Surgery
Status: NOT_YET_RECRUITING
Conditions: Trendelenburg|Neumoperitoneum|Oxygenation|Respiratory|Pulmonary
Interventions: OTHER: group L (Vt 6 ml/kg)|OTHER: group I (Vt 8 ml/kg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of 9MW1911 Injection in Healthy Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma|COPD|Atopic Dermatitis
Interventions: DRUG: Experimental drug 9MW1911|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Food Based Intervention Rich in Plant Components to Improve Metabolic Health in Prediabetics (FBIP) Study
Status: UNKNOWN
Conditions: Diabetes
Interventions: COMBINATION_PRODUCT: Low Calorie Meals Rich in Plant Components|COMBINATION_PRODUCT: Low Calorie Balanced Meals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Multimodal Prehabilitation To Improve The Clinical Outcomes Of Frail Elderly Patients With Gastric Cancer
Status: RECRUITING
Conditions: Stomach Neoplasms|Frail Elderly
Interventions: BEHAVIORAL: Multimodal prehabilitation program|BEHAVIORAL: ERAS protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Central Neck Dissection for Papillary Thyroid Cancer
Status: COMPLETED
Conditions: Papillary Thyroid Cancer
Interventions: PROCEDURE: Total thyroidectomy|PROCEDURE: Total thyroidectomy + prophylactic central neck dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of High-Fat Ketogenic Diet and Low-Fat Diet in Women Body Weight
Status: RECRUITING
Conditions: Overweight and Obesity|Healthy
Interventions: OTHER: A randomized acute controlled trial of twenty-eight healthy overweight or obese women
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of a Psychosomatic Symptom Intervention Program on the Primary Treatment of Differentiated Thyroid Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pathologically Confirmed Differentiated Thyroid Carcinoma|All Patients Are in the Initial Treatment Phase|Normal Cognitive and Communicative Abilities, Capable of Reading and Understanding Questionnaires in Chinese|Ability to Use a Smartphone|Voluntary Participation in the Study and Signed Informed Consent
Interventions: OTHER: Psychosomatic Symptoms Intervention|OTHER: Extended supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study of Fruquintinib in Combination With Irinotecan and Capecitabine for the Second-line Treatment of Patients
Status: RECRUITING
Conditions: Fruquintinib|Irinotecan|Capecitabine|Gastrointestinal Tumours
Interventions: DEVICE: fruquintinib|DRUG: Irinotecan|DRUG: Capecitabine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of PK of AC1204 v Caprylic Triglyceride Oil Incl Food Effect on Ketone Body Production
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AC-1204|DRUG: caprylic triglyceride oil (standard breakfast)|DRUG: caprylic triglyceride oil (high fat breakfast)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Pilot Trial of Fecal Microbiota Transplantation for Lymphoma Patients Receiving Axicabtagene Ciloleucel Therapy.
Status: RECRUITING
Conditions: Lymphoma
Interventions: DRUG: Fecal Microbiota Transplantation|PROCEDURE: Chemotherapy|PROCEDURE: CAR-T Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Early Botulinum Toxin A Injection for Lower Limbs Spasticity in Subacute Stroke Adults
Status: UNKNOWN
Conditions: Stroke|Muscle Spasticity
Interventions: DRUG: BoNT-A injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Associations of Communication Skills Workshop and Improvements in Stress, Burnout and Empathy and Psychometric Properties of Chinese Version of Perceived Stress Scale, Professional Fulfillment and Burnout Scale and Empathy Among Health Care Professionals
Status: UNKNOWN
Conditions: Stress
Interventions: BEHAVIORAL: Workshop of Enhancing Interpersonal Effectiveness, Emotional Regulation and Clinical Communication Skills
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: tACS Improves Memory in Elders With Subjective Memory Complaints
Status: COMPLETED
Conditions: Memory Deficits|tACS
Interventions: DEVICE: active tACS|DEVICE: sham tACS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Post-Market Observational Registry of the NeoChord Artificial Chordae Delivery System
Status: RECRUITING
Conditions: Mitral Regurgitation|Mitral Valve Disease|Mitral Valve Insufficiency|Mitral Valve Prolapse|Heart Valve Diseases
Interventions: DEVICE: NeoChord Artificial Chordae Delivery System, Model DS1000
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Prospective Trial to Reduce Post-Operative Pain in Implant Based Breast Reconstruction
Status: TERMINATED
Conditions: Post-operative Pain
Interventions: DRUG: Bupivacaine|DRUG: Botulinum Toxins|DRUG: Analgesics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of DS-7011a in Patients With Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: DS-7011a|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Routine Or Selective Stress Testing After Revascularization: ROSSTAR Trial RCT Outline
Status: UNKNOWN
Conditions: Coronary Heart Disease|Coronary Artery Disease
Interventions: OTHER: Observation|DIAGNOSTIC_TEST: Nuclear Perfusion Imaging Stress Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Anesthesia on Optic Nerve Sheath Diameter in Patients Undergoing Robot-assisted Laparoscopic Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Total intravenous anesthesia|PROCEDURE: Inhalation anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of Treating HIV-Positive Patients With an HIV Vaccine (Remune)
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: Lamivudine/Zidovudine|BIOLOGICAL: HIV-1 Immunogen|DRUG: Nelfinavir mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Dual Action Pneumatic Compression System: Tolerance and Comfort in Patients With Venous Leg Ulcers (VLUs)
Status: COMPLETED
Conditions: Venous Leg Ulcer|Chronic Venous Insufficiency|Venous Stasis Ulcer|Venous Ulcer|Venous Insufficiency
Interventions: DEVICE: Dual Action Pneumatic Compression
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Berberine on Intestinal Function and Inflammatory Mediators in Severe Patients With Covid-19
Status: COMPLETED
Conditions: Berberine|COVID-19
Interventions: DRUG: Berberine|DRUG: Montmorrillonite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Uretersocopy With Versus Without Use of Guide-wire in Treatment of Ureteral Stone
Status: COMPLETED
Conditions: Ureteral Calculi
Interventions: PROCEDURE: ureteroscopy with safety guide-wire|PROCEDURE: ureteroscopy alone|PROCEDURE: without safety guide-wire|PROCEDURE: with safety guide-wire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide
Status: RECRUITING
Conditions: Pre-Eclampsia|Gestational Hypertension|Superimposed Pre-Eclampsia|Hypertension, Pregnancy-Induced|Postpartum Pregnancy-Induced Hypertension|Postpartum Preeclampsia
Interventions: DRUG: Hydrochlorothiazide 50mg Tablet|DRUG: Placebo Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound-based Imaging to Detect Early Changes of Hard and Soft Tissue Around Immediately Placed Implants With or Without Soft Tissue Augmentation
Status: ENROLLING_BY_INVITATION
Conditions: Tooth Extraction|Immediate Implant Placement
Interventions: DEVICE: Xenogeneic Volume-Stable Collagen Matrix (VCMX) graft No Intervention: No Soft Tissue Augmentation|PROCEDURE: Tuberosity Connective Tissue Graft (CTG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Protein Dairy Products and Resistance Exercise in the Elderly
Status: COMPLETED
Conditions: Dairy Products|Whey Protein|Resistance Training|Older Adults
Interventions: OTHER: Whey Protein+Resistance Training|OTHER: High protein yogurt+Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Serum Testosterone and Nestorone in Females After Secondary Exposure to Nestorone ® (NES) + Testosterone (T) Combined Gel Applied to Shoulders and Upper Arms in Males
Status: COMPLETED
Conditions: Healthy Men|Male Contraception|Healthy Women|Product Transference
Interventions: DRUG: Nestorone + Testosterone Combination Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bone Mineral Density in Postmenopausal Women With Primary Breast Cancer Who Are Receiving Treatment on Clinical Trial
Status: COMPLETED
Conditions: Breast Cancer|Osteoporosis
Interventions: DIETARY_SUPPLEMENT: calcium carbonate|DIETARY_SUPPLEMENT: calcium citrate|DIETARY_SUPPLEMENT: cholecalciferol|DRUG: alendronate sodium|DRUG: calcium gluconate|DRUG: risedronate sodium|OTHER: laboratory biomarker analysis|PROCEDURE: dual x-ray absorptometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Two Dosage Strengths of Transdermal Fentanyl Versus Transdermal Buprenorphine and Placebo in Acute Pain Models in Healthy Volunteers.
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Fentanyl; Buprenorphine; Naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Experimental Medicine Study to Validate Pharmacodynamic Pain Assessments in Healthy Volunteers With an Opioid Analgesic (Remifentanil)
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Remifentanil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose:
Clinical trial: Mechanisms of Antidepressant Non-Response in Late-Life Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Escitalopram|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Monotherapy vs. TACE-sorafenib Sequential Therapy for HCC With Metastasis
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Metastasis
Interventions: PROCEDURE: transarterial chemoembolization (TACE)|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Initial Management of Patients Receiving a Single Shock (IMPRESS)
Status: TERMINATED
Conditions: Ventricular Tachycardia
Interventions: PROCEDURE: Ventricular Tachycardia Ablation|OTHER: Standard Medical Therapy|PROCEDURE: Non-Invasive Programmed Stimulation (NIPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Confirmatory Clinical Trial to Evaluate the Safety and Efficacy of "AG NPP709 Syrup"
Status: COMPLETED
Conditions: Acute Upper Respiratory Tract Infections|Bronchitis
Interventions: DRUG: AG NPP709syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase IB Study to Determine the Safety and Tolerability of Canakinumab and Tislelizumab in Combination With Nab-Paclitaxel and Gemcitabine in the Neo-adjuvant Treatment of Patients With Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: Canakinumab|DRUG: Tislelizumab|DRUG: Nab-Paclitaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Pharmacokinetics of BX-001N in Healthy Participants
Status: RECRUITING
Conditions: Ischemia-reperfusion Injury
Interventions: DRUG: BX-001N Part 1|DRUG: BX-001N Part 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Knowledge and Interpersonal Skills to Develop Exemplary Relationships (KINDER): Pilot Study
Status: COMPLETED
Conditions: Dementia|Caregiver Burden|Relation, Family|Elder Abuse
Interventions: BEHAVIORAL: Knowledge and Interpersonal Skills to Develop Exemplary Relationships
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Antenatal Detection by Array CGH Genomic Rearrangements Unbalanced Front Uninsulated Thick Neck or a Combination of Two Signs of Ultrasound Calling Normal Karyotype
Status: COMPLETED
Conditions: Abnormality of the Neck|Fetus; Abnormal, Affecting Management of Pregnancy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Carboplatin, Paclitaxel, and Everolimus in Treating Patients With Previously Untreated Cancer of Unknown Primary
Status: COMPLETED
Conditions: Carcinoma of Unknown Primary Origin
Interventions: DRUG: carboplatin|DRUG: everolimus|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Aplindore in Patients With Early Parkinson Disease
Status: TERMINATED
Conditions: Early Parkinson Disease
Interventions: DRUG: aplindore MR tablets or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Analysis for Treatment Choice in Gestational Diabetes Mellitus
Status: COMPLETED
Conditions: Gestational Diabetes|Diabetes, Gestational|Pregnancy in Diabetes
Interventions: DRUG: Insulin|DRUG: Glyburide|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Jet Lidocaine for Pain Relief During Needle Insertion in a Pediatric Emergency Department
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Lidocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Adalimumab in Patients With Active Rheumatoid Arthritis Treated Concomitantly With Methotrexate.
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Adalimumab|BIOLOGICAL: Adalimumab|DRUG: Placebo|BIOLOGICAL: Adalimumab|BIOLOGICAL: Adalimumab|BIOLOGICAL: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Dacomitinib With or Without Osimertinib for Patients With Metastatic EGFR Mutant Lung Cancers With Disease Progression on Osimertinib.
Status: COMPLETED
Conditions: EGFR Gene Mutation|Lung Cancer|Lung Cancer Metastatic
Interventions: DRUG: Dacomitinib|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of ELX-02 in Healthy Adults
Status: COMPLETED
Conditions: Genetic Disease|Nonsense Mutation
Interventions: DRUG: Placebo|DRUG: ELX-02
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enterotoxigenic Escherichia Coli (ETEC) ETVAX Vaccine Trial in Bangladesh
Status: COMPLETED
Conditions: Escherichia Coli Diarrhea
Interventions: BIOLOGICAL: ETVAX|BIOLOGICAL: dmLT|OTHER: Bicarbonate Buffer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Alpha-blockers (Tamsulosin) in the Treatment of Symptomatic Dysuria in Multiple Sclerosis in Women
Status: RECRUITING
Conditions: Multiple Sclerosis|Dysuria|Lower Urinary Tract Symptoms|Voiding Dysfunction|Urinary Retention
Interventions: DRUG: Tamsulosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of TBF Regimen in Allo-HSCT in Patients With CNS Leukemia
Status: NOT_YET_RECRUITING
Conditions: Central Nervous System Leukemia|Allogeneic Hematopoietic Stem Cell Transplantation
Interventions: DRUG: TBF regimen|DRUG: modified BuCY2 regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Divided or Single Exposure (DOSE) Study
Status: RECRUITING
Conditions: Opioid Use Disorder|Chronic Pain|Methadone
Interventions: DRUG: Methadone (100% dose)|DRUG: Methadone (50% dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Which Nostril Should be Used for Nasotracheal Intubation With Airtraq NT®: the Right or Left? A Randomized Clinical Trial
Status: COMPLETED
Conditions: Nasotracheal Intubation
Interventions: DEVICE: Airtraq NT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Mesalamine to Reduce T Cell Activation in HIV Infection
Status: COMPLETED
Conditions: HIV Infections|Sexually Transmitted Diseases|Immune System Diseases|Lentivirus Infections|Acquired Immunodeficiency Syndrome
Interventions: DRUG: Mesalamine (5-aminosalicylic acid, Apriso)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of a Novel Thrombectomy Device to Treat Acute Iliofemoral Deep Venous Thrombosis
Status: UNKNOWN
Conditions: Venous Thrombosis
Interventions: DEVICE: a manual spiral thrombus broken suction device|PROCEDURE: catheter-directed thrombolysis|DRUG: low-molecular-weight heparin calcium|DRUG: urokinase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The PIO II Study: In-office Post-op Placement of a Steroid-eluting Sinus Implant
Status: COMPLETED
Conditions: Chronic Sinusitis, Ethmoidal
Interventions: COMBINATION_PRODUCT: Steroid-eluting sinus implant|OTHER: Post-op standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: THERMOCOOL® SMARTTOUCH™ Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Heart Diseases|Arrhythmia|Atrial Fibrillation
Interventions: DEVICE: THERMOCOOL® SMARTTOUCH™ Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of PA21 in Hemodialysis Patients With Hyperphosphatemia
Status: COMPLETED
Conditions: Hemodialysis|Hyperphosphatemia
Interventions: DRUG: PA21|DRUG: Sevelamer hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Placebo-Controlled Study of Collagen Hydrolysate in Subjects With Knee Osteoarthritis (OA)
Status: COMPLETED
Conditions: Knee Osteoarthritis (OA)
Interventions: DIETARY_SUPPLEMENT: Collagen Hydrolysate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Severe Childhood Aggression (The TOSCA Study)
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Methylphenidate HCl|DRUG: Risperidone|BEHAVIORAL: Parent Management Training (PMT)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Performance and Patient Acceptance of a Commercially Available Beverage as Compared to an Oral Glucose Solution for Oral Glucose Tolerance Tests in Cystic Fibrosis (CF) Patients Who Are Screened for CF-related Diabetes.
Status: UNKNOWN
Conditions: Cystic Fibrosis|Cystic Fibrosis-related Diabetes
Interventions: DIAGNOSTIC_TEST: OGTT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 3 Study of Brentuximab Vedotin (SGN-35) in Patients at High Risk of Residual Hodgkin Lymphoma Following Stem Cell Transplant (The AETHERA Trial)
Status: COMPLETED
Conditions: Disease, Hodgkin
Interventions: DRUG: brentuximab vedotin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluoroscopic Versus Ultrasound Guidance for Cooled Radiofrequency Ablation of Geniculate Nerves in Knee Osteoarthritis: A Randomized Control Trial
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: cRFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cisplatin and Gemcitabine With or Without Bevacizumab in EGFR Wild-type Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: cisplatin and gemcitabine combination with Bevacizumab|DRUG: Gemcitabine combined with cisplatin chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EMPagliflozin After Aortic Valve Replacement
Status: RECRUITING
Conditions: Aortic Valve Stenosis
Interventions: DRUG: Empagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Substance Abuse Treatment to HIV Care (SAT2HIV): The Motivational Interviewing-based Brief Intervention Experiment
Status: COMPLETED
Conditions: Substance Use
Interventions: BEHAVIORAL: Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Levetiracetam for Alzheimer's Disease Neuropsychiatric Symptoms Related to Epilepsy Trial (LAPSE)
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise-induced Changes in Cardiac Function & Morphology
Status: COMPLETED
Conditions: Myocardial Ischemia|Exercise|Myocardial Contraction|Myocardial Stunning|Heart Failure
Interventions: OTHER: Strenuous Endurance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multiple-Dose Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of BMS-779788 in Healthy Subjects
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DRUG: BMS-779788|DRUG: BMS-779788|DRUG: BMS-779788|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Onychomycosis Using a 0.65 Millisecond Pulsed Nd:YAG 1064 nm Laser
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DEVICE: Laser Treatment (Pulsed Nd:YAG 1064 nm Laser)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HepATocellular Cancer Hcv Therapy Study
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma|Hepatoma|Liver Cell Carcinoma|Hepatitis C
Interventions: DRUG: Elbasvir / Grazoprevir Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Edoxaban for TIA and Acute Minor Stroke
Status: UNKNOWN
Conditions: Ischemia|Stroke|Cerebral Infarction
Interventions: DRUG: Aspirin|DRUG: edoxaban|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Standard Pulsed Radiofrequency Versus Supervoltage Pulsed Radiofrequency Glossopharyngeal Nerve in Oropharyngeal Cancer Pain
Status: RECRUITING
Conditions: Pulsed Radiofrequency|Super Voltage Pulsed Radiofrequency|Glossopharyngeal Nerve|Oropharyngeal Cancer|Pain
Interventions: PROCEDURE: Supervoltage pulsed radiofrequency glossopharyngeal nerve block|PROCEDURE: Standard voltage pulsed radiofrequency glossopharyngeal nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acetaminophen and AKI After Aortic Surgery
Status: RECRUITING
Conditions: Aortic Surgery
Interventions: DRUG: Acetaminophen|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Autologous Platelet-rich Plasma as a Treatment for Macular Holes
Status: COMPLETED
Conditions: Macular Holes|Macular Hole of Left Eye (Disorder)|Macular Hole of Right Eye (Disorder)
Interventions: PROCEDURE: Pars plana vitrectomy, with or without epiretinal membrane peeling, plus PRGF membrane implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Teenage/Young Adults and Paediatric Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition
Status: RECRUITING
Conditions: Malignancy|Malignant Neoplasm|Lymphoproliferative Disorders|Neoplasms by Histologic Type|Neoplasms by Site|Cancer|Colorectal Neoplasms|Endometrial Neoplasms|Melanoma
Interventions: DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does an Additional Antirotation U-Blade (RC) Lagscrew Improve Treatment of AO/OTA (Orthopaedic Trauma Association) 31 A1-3 Fractures With Gamma 3 Nail?
Status: COMPLETED
Conditions: Hip Fractures
Interventions: PROCEDURE: Fractures were treated with a Gamma 3 intramedullary nail|PROCEDURE: Fractures were treated with a Gamma 3 intramedullary nail + U-Blade
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Effects of Iron Levels on the Lungs at High Altitude
Status: COMPLETED
Conditions: Pulmonary Hypertension|Mountain Sickness
Interventions: DRUG: Iron sucrose|DRUG: Normal saline|PROCEDURE: Venesection|DRUG: Iron sucrose|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Laryngoscopy for Neonatal and Infant aIrway Management (Optimise-Trial)
Status: COMPLETED
Conditions: Airway Management
Interventions: DEVICE: C-MAC indirect videolaryngoscope with blades Miller nr 0 and Miller nr 1.|DEVICE: Direct laryngoscope with blades Miller nr 0 and Miller nr 1.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of a Multiple-dose Oral Administration of CG5503 PR on the Electrical Activity of the Heart in 48 Healthy Men and Women
Status: COMPLETED
Conditions: Prolonged QTc Interval|Pharmacokinetic
Interventions: DRUG: 100 mg CG5503 (tapentadol hydrochloride) PR tablet|DRUG: Placebo matching CG5503 PR tablet|DRUG: Placebo matching moxifloxacin capsule|DRUG: 400 mg Moxifloxacin tablet (overencapsulated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Shock Wave Therapy on Truncal Obesity and Lipid Profile in Obese Post Menopausal Women
Status: COMPLETED
Conditions: Obesity
Interventions: DEVICE: shock wave|OTHER: Moderate intensity aerobic exercise|OTHER: Energy-restricted diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of Respiratory Physiotherapy in Infants With Moderate Acute Bronchiolitis
Status: UNKNOWN
Conditions: Acute Bronchiolitis
Interventions: OTHER: Chest Physiotherapy|OTHER: Surveillance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Photobiomodulation by 808nm Diode Laser on the Stability of Orthodontic Mini-implants.
Status: COMPLETED
Conditions: Malocclusion, Angle Class II
Interventions: PROCEDURE: Irradiation of implants with 808nm laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of NN5401 in Japanese Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec/insulin aspart|DRUG: biphasic insulin aspart 30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does the Non-surgical Application of Enamel Matrix Derivative Reduce the Need of Periodontal Surgical Intervention in Subjects With Severe (Stage III) Periodontitis?
Status: RECRUITING
Conditions: Periodontal Diseases
Interventions: DRUG: Enamel Matrix Derivative application|OTHER: Saline application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Surufatinib Combined With Sintilimab and SCRT in Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Unresectable Advanced Solid Tumors|Biliary Tract Tumors, Gastric Cancer, Small Cell Lung Cancer
Interventions: DRUG: Surufatinib|DRUG: Sintilimab|RADIATION: Short course radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of TENS Applied in the Early Postpartum Period on Incision Healing, Pain and Comfort
Status: COMPLETED
Conditions: Postoperative Recovery|Wound Healing|Postpartum Comfort|Postpartum Pain
Interventions: OTHER: Transcutaneous Electrical Nerve Stimulation (TENS)|OTHER: Plasebo-Fake TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of Nitroglycerine to Improve Signs of Poor Peripheral Perfusion in Patients With Traumatic Hemorrhagic Shock
Status: UNKNOWN
Conditions: Hemorrhagic Shock
Interventions: DRUG: Nitroglycerin patch 5mg|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of Extracorporeal Shockwave Therapy in Patients With Patellar Tendinopathy on Its Micromorphology
Status: ENROLLING_BY_INVITATION
Conditions: Patellar Tendinopathy
Interventions: DEVICE: BTL-6000 FSWT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Coronary Artery Ectasia in Elective Coronary Angiography : Predictors, Outcomes and Management
Status: COMPLETED
Conditions: Ectasia|Coronary Artery Disease
Interventions: DRUG: Antiplatelet Agents|DRUG: Anticoagulants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HLA-mismatched MST vs HLA-matched NST for AML in Intermediate-risk
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: GENETIC: HLA mismatched stem cell|GENETIC: HLA matched stem cell|DRUG: cyclosporine A|DRUG: Mycophenolate mofetil|DRUG: Ara-C|DRUG: fludarabine|DRUG: anti-lymphocyte globulin|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Continuing CHemotherapy in Overt Left Ventricular Dysfunction Using Antibodies to HER-2
Status: COMPLETED
Conditions: Heart Failure|Breast Cancer
Interventions: DRUG: standard-of-care treatments for LV impairment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pregabalin in the Prevention of Central Neuropathic Pain in Acute Spinal Cord Injury
Status: TERMINATED
Conditions: Spinal Cord Trauma|Pain
Interventions: DRUG: Lyrica|DRUG: matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety and Efficacy Study of CNTO 328 in Patients With B-Cell Non-Hodgkin's Lymphoma, Multiple Myeloma, or Castleman's Disease
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|Multiple Myeloma|Giant Lymph Node Hyperplasia
Interventions: DRUG: CNTO 328
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of Single-dose Administration of Brexpiprazole in Adult Subjects With Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Brexpiprazole, OPDC-34712
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Surgery Plus Target-reduction Chemoradiotherapy vs Regular Chemoradiotherapy for Newly Diagnosed Resectable Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin|RADIATION: regular intensity-modulated radiotherapy|PROCEDURE: surgery|RADIATION: Target-reduction intensity-modulated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Modified Free Gingival Graft Technique
Status: NOT_YET_RECRUITING
Conditions: Modified Free Gingival Graft , Connective Tissue Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Community Based Interventions to Improve HIV Outcomes in Youth: a Cluster Randomised Trial in Zimbabwe
Status: COMPLETED
Conditions: HIV Infection
Interventions: OTHER: Community-based package of integrated HIV, SRH and general health services
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of Er:YAG Pulse Therapy for Achieving Pre-emptive Dental Analgesia in Children
Status: COMPLETED
Conditions: Caries, Dental
Interventions: PROCEDURE: Laser analgesic procedure|PROCEDURE: Placebo analgesic procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic Versus Open Primary Ventral Hernia Repair
Status: ACTIVE_NOT_RECRUITING
Conditions: Ventral Hernia
Interventions: PROCEDURE: Robotic ventral hernia repair|PROCEDURE: Open ventral hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of AGB101 for Mild Cognitive Impairment
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment|Prodromal Alzheimer's Disease
Interventions: DRUG: AGB101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Human Recombinant Erythropoietin in Acute Renal Failure
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: erythropoietin|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT