pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of Manuka Eye Drops on Tear Film Properties
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: OTHER: Optimel Antibacterial Manuka+ Dry Eye Drops|OTHER: Systane Ultra Lubricating Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Upper Extremity Elevation and Lungfunction After Open Heart Surgery
Status: COMPLETED
Conditions: Heart Diseases|Heart Diseases, Ischemic|Heart Disease, Valvular
Interventions: OTHER: upper extremity elevation|OTHER: upper extremity elevation with deep breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Liver Protection Using Prednisone for Patients Receiving Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of S5G4T-1 in the Treatment of Papularpustular Rosacea
Status: COMPLETED
Conditions: Papulopustular Rosacea
Interventions: DRUG: S5G4T-1|DRUG: S5G4T-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Veliparib, Carboplatin, and Paclitaxel in Treating Patients With Advanced Solid Cancer
Status: COMPLETED
Conditions: Adult Solid Neoplasm|BRCA1 Mutation Carrier|BRCA2 Mutation Carrier|Hereditary Breast and Ovarian Cancer Syndrome
Interventions: DRUG: Carboplatin|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|OTHER: Pharmacological Study|DRUG: Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GM-CSF, Rituximab, and Combination Chemotherapy in Treating Patients With Previously Untreated Advanced Follicular Non-Hodgkin Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|BIOLOGICAL: sargramostim|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: prednisone|DRUG: vincristine sulfate|GENETIC: gene expression analysis|GENETIC: gene rearrangement analysis|GENETIC: polymerase chain reaction|OTHER: R-CHOP regimen|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Before and After Erythrocyte Suspension Transfusion
Status: COMPLETED
Conditions: Anemia|Oxidative Stress
Interventions: OTHER: Before Erythrocyte Suspension (ES)|OTHER: After Erythrocyte Suspension (ES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Abatacept vs Tocilizumab for the Treatment of RA in TNF Alpha Inhibitor Inadequate Responders
Status: RECRUITING
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Tocilizumab Prefilled Syringe|DRUG: Abatacept Prefilled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fresh Carts for Mom's to Improve Food Security and Glucose Management
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus in Pregnancy|Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: Fresh Funds for Mom's|BEHAVIORAL: Standard Medical care|BEHAVIORAL: Medically Tailored Frozen Meals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Safety and Immunogenicity Evaluation of Live Attenuated Influenza Vaccine
Status: UNKNOWN
Conditions: Influenza Prevention
Interventions: BIOLOGICAL: Live Attenuated Influenza Vaccine|BIOLOGICAL: Live Attenuated Influenza Vaccine placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Uterus Transplantation From Deceased Donor - Gothenburg III
Status: COMPLETED
Conditions: Absolute Uterine Factor Infertility|Transplantation|Mrk Anomaly
Interventions: PROCEDURE: uterus transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified TOMOX-HAIC in Combination With Sintilimab and Bevacizumab Biosimilar for First-line Treatment of Advanced Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: TOMOX-HAIC|DRUG: Sintilimab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomised Trial Evaluating the Benefit of a Fitness Tracker Based Workout During Radiotherapy
Status: RECRUITING
Conditions: Bronchial Carcinoma|Esophageal Carcinoma|Tumor of the Brain|Head and Neck Cancer|Pancreas Cancer|Sarcoma|Cervix Uteri Cancer
Interventions: DEVICE: Fitness tracker based activity training for Arm A and B. Booklet "physical training, exercise and cancer" and an introduction about physical activity during cancer therapy for Arm A, B, C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Repeated Dose Study of KHK6640 in Japanese Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: KHK6640|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Gender Stereotypes on Fiberoptic Intubation Performance
Status: COMPLETED
Conditions: Stereotype-threat|Intubation; Difficult or Failed|Gender
Interventions: BEHAVIORAL: stereotype threat manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation Of The Importance Of Risk-Factor Adjustment For Assessing The Relationship Between Voriconazole Utilization And The Development Of Non-Melanoma Skin Cancer Among Lung And Heart/Lung Transplant Patients, 2002-2009g
Status: COMPLETED
Conditions: Non-Melanoma Skin Carcinoma
Interventions: DRUG: voriconazole (Vfend)|OTHER: no voriconazole (Vfend)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Tirzepatide (LY3298176) Versus Semaglutide Once Weekly as Add-on Therapy to Metformin in Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Tirzepatide|DRUG: Semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Lesions
Status: COMPLETED
Conditions: Anal Cancer|High-grade Squamous Intraepithelial Lesion|HIV Infection|Human Papilloma Virus Infection
Interventions: DRUG: imiquimod|DRUG: fluorouracil|DEVICE: infrared photocoagulation therapy|DEVICE: thermal ablation therapy|DEVICE: laser therapy|OTHER: clinical observation|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Obturator Nerve Block in Patients With Hip Fracture
Status: WITHDRAWN
Conditions: Hip Fractures
Interventions: DRUG: Bupivacaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mucin Balls and Corneal Inflammation Events
Status: COMPLETED
Conditions: Corneal Inflammation|Corneal Infiltrative Events
Interventions: DEVICE: lotrafilcon A|DEVICE: comfilcon A|DEVICE: balafilcon A|OTHER: etafilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Total Neoadjuvant Therapy for Adenocarcinoma of the OESophagus and Oesophagogastric Junction: TNT-OES-2 Trial
Status: NOT_YET_RECRUITING
Conditions: Esophageal Cancer|Adenocarcinoma of the Esophagus
Interventions: DRUG: FLOT-CROSS or CROSS-FLOT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of the Maastro Applicator in Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Rectal Cancer|Feasibility|Toxicity|Quality of Life|Radiation Toxicity|Radiation Proctitis|Brachytherapy|Complete Response
Interventions: DEVICE: Maastro applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation Intervention for Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Newly Diagnosed Cancer Patients
Interventions: BEHAVIORAL: Hospital Counseling + Nicotine Replacement Therapy. questionaires|BEHAVIORAL: Hospital Counseling + Nicotine Replacement + Presurgical Scheduled Reduced Smoking, questionaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nuedexta for the Prevention and Modification of Disease Progression in Episodic Migraine
Status: COMPLETED
Conditions: Episodic Migraine
Interventions: DRUG: Dextromethorphan and quinidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sitagliptin for Hyperglycemia in Patients With T2DM Undergoing Cardiac Surgery
Status: COMPLETED
Conditions: Hyperglycemia
Interventions: DRUG: Sitagliptin|DRUG: Placebo|DRUG: Regular Human Insulin|DRUG: Insulin glargine|DRUG: Supplemental insulin (Insulin lispro)|DRUG: Supplemental insulin (Insulin aspart)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Mini-flap BABA (Bilateral Axillo-breast Approach) Robotic Thyroidectomy is Safe
Status: UNKNOWN
Conditions: Thyroid Nodule
Interventions: PROCEDURE: Mini-flap|PROCEDURE: Conventional flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A New Non-invasive Method to Assess and Measure Palatal Masticatory Mucosa Using Dynamic Navigation System
Status: RECRUITING
Conditions: Palatal Masticatory Mucosa Thickness
Interventions: DIAGNOSTIC_TEST: palatal masticatory mucosa thickness measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Loaded Vs Unloaded Sit to Stand Strengthening Exercises in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Loaded sit to stand strengthening exercise|OTHER: Unloaded sit to stand strengthening exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Whether Pembrolizumab Alone or in Combination With CMP-001 Improves Efficacy in Patients With Operable Melanoma
Status: SUSPENDED
Conditions: Clinical Stage III Cutaneous Melanoma AJCC v8|Melanoma of Unknown Primary|Pathologic Stage IIIB Cutaneous Melanoma AJCC v8|Pathologic Stage IIIC Cutaneous Melanoma AJCC v8|Pathologic Stage IIID Cutaneous Melanoma AJCC v8|Recurrent Cutaneous Melanoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|BIOLOGICAL: Pembrolizumab|PROCEDURE: Positron Emission Tomography|PROCEDURE: Surgical Procedure|DRUG: VLP-encapsulated TLR9 Agonist CMP-001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ib Study of Anetumab Ravtansine in Combination With Pegylated Liposomal Doxorubicin in Patients With Recurrent Mesothelin-expressing Platinum-resistant Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasms
Interventions: DRUG: Anetumab ravtansine (BAY94-9343)|DRUG: Pegylated Liposomal Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impacts of Two Rehabilitation Programs on Chronic Peripheral Facial Paresis
Status: UNKNOWN
Conditions: Facial Palsy|Self-rehabilitation|Quality of Life|Motor Recovery
Interventions: OTHER: Self-rehabilitation program|OTHER: Conventional rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Injectable Lidocaine Versus Lidocaine/Tetracaine Patch for the Incision and Drainage of Skin Abscesses
Status: COMPLETED
Conditions: Cutaneous Abscess|Pain
Interventions: DRUG: Lidocaine/tetracaine patch|DRUG: 1% lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Roxadustat in the Treatment of Anemia in Chronic Kidney Disease (CKD) Patients, Not on Dialysis, in Comparison to Darbepoetin Alfa
Status: COMPLETED
Conditions: Anemia in Chronic Kidney Disease in Non-dialysis Patients
Interventions: DRUG: Roxadustat|DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Bioptron Light on Carpal Tunnel Syndrome(BLCTS)
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome Pregnancy
Interventions: DEVICE: bioptron light therapy|DEVICE: wrist brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomised Controlled Trial to Assess Whether Computed Tomography Cardiac Angiography Can Improve Invasive Coronary Angiography in Bypass Surgery Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Ischaemic Heart Disease|Contrast-induced Nephropathy
Interventions: DIAGNOSTIC_TEST: CTCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Venetoclax, Azacitidine, and Lintuzumab-Ac225 in AML Patients
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia|Relapsed Adult AML
Interventions: BIOLOGICAL: Lintuzumab-Ac225|DRUG: Venetoclax|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of BAY94-9027 in Previously Treated Male Children With Haemophilia A
Status: COMPLETED
Conditions: Hemophilia A
Interventions: BIOLOGICAL: BAY94-9027|BIOLOGICAL: BAY94-9027|BIOLOGICAL: BAY94-9027
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD8+ T-cell PET/CT Imaging in COVID-19 Patients
Status: UNKNOWN
Conditions: Lymphopenia Due to COVID-19|T-cell|PET Imaging
Interventions: DIAGNOSTIC_TEST: [89Zr]Df-IAB22M2C PET/CT scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nilotinib + Pegylated Interferon Alpha 2a for Untreated Chronic Phase Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia
Interventions: DRUG: Nilotinib,Novartis,300 mg twice a day +Pegylated interferon 2a,Roche, 45 microg weekly starting Month 2-Month 12 or beyond according to investigator choice.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chloroprocaine Lavage to Improve Outcomes Related to Operative Cesarean Delivery
Status: UNKNOWN
Conditions: Cesarean Section
Interventions: DRUG: Preservative free 1% Chloroprocaine|DRUG: Preservative free 2% Chloroprocaine|DRUG: Preservative free 3% Chloroprocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of DCR-A1AT in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Alpha 1-Antitrypsin Deficiency
Interventions: DRUG: belcesiran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: TAK-659 and Paclitaxel in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Malignant Solid Neoplasm|Ovarian Carcinoma|Refractory Malignant Solid Neoplasm|Refractory Ovarian Carcinoma
Interventions: DRUG: Mivavotinib|DRUG: Paclitaxel|OTHER: Pharmacokinetic Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual Treatment of Chronic Pain and Insomnia
Status: COMPLETED
Conditions: Insomnia|Chronic Pain
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia (CBT-I)|BEHAVIORAL: Interdisciplinary Pain Rehabilitation Program (IPRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of SM04554 Topical Solution in Male Subjects With Androgenetic Alopecia
Status: COMPLETED
Conditions: Androgenetic Alopecia
Interventions: DRUG: Topical SM04554 solution|DRUG: Topical SM04554 solution|DRUG: Topical vehicle solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First Line Atezolizumab, Paclitaxel, and Bevacizumab (Avastin®) in mTNBC
Status: COMPLETED
Conditions: Metastatic Breast Cancer|Advanced Breast Cancer|Triple Negative Breast Cancer
Interventions: DRUG: Atezolizumab|DRUG: Paclitaxel|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Transcutaneous Electrical Acupoint Stimulation in Laparoscopic Cholecystectomy
Status: NOT_YET_RECRUITING
Conditions: Pain Postoperative|Postoperative Recovery
Interventions: OTHER: Transcutaneous electrical acupoint stimulatios|OTHER: Bilateral transverse abdominal plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ascorbic Acid Versus Diode Laser in the Treatment of Gingival Hyperpigmentation
Status: COMPLETED
Conditions: Gingival Hyperpigmentaion
Interventions: DRUG: Ascorbic Acid 500 MG|DEVICE: diode laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Frequent Standardized Oral Care to Improve Health Outcomes in Premature Infants in the Neonatal Intensive Care Unit
Status: ACTIVE_NOT_RECRUITING
Conditions: Microbial Colonization|Ventilator Associated Pneumonia
Interventions: OTHER: frequent standardized oral care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Feasibility of a Patient Directed Tool to Assess Heart Health Among Endometrial Cancer Survivors
Status: COMPLETED
Conditions: Endometrial Cancer|Survivorship
Interventions: OTHER: PREVENT Cardiovascular Health Assessment Tool|OTHER: Survey|OTHER: Interview Regarding Heart Health
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: X-Ray Study Investigating The Safety And Efficacy Of SD-6010 In Subjects With Osteoarthritis Of The Knee
Status: WITHDRAWN
Conditions: Knee Osteoarthritis
Interventions: DRUG: SD-6010|DRUG: SD-6010|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Partners and Alerts: A Study of Social Forces in Medication Adherence
Status: COMPLETED
Conditions: Acute Myocardial Infarction (AMI)
Interventions: BEHAVIORAL: Electronic Pill Bottle tracking|BEHAVIORAL: Adherence Messaging|BEHAVIORAL: Social Influence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effectiveness of Activity Trackers to Reduce Sedentary Behaviour in Sedentary Adults
Status: COMPLETED
Conditions: Sedentary Lifestyle
Interventions: DEVICE: CWAT intervention|DEVICE: CWAT + motivation intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Methyl Aminolevulinate + Daylight in Patients With Facial Photodamage
Status: COMPLETED
Conditions: Facial Photodamage
Interventions: DRUG: Methyl Aminolevulinate (MAL)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Anti-inflammatory Radiotherapy for the Treatment of Pneumonia by COVID-19
Status: UNKNOWN
Conditions: Pneumonia, Viral
Interventions: RADIATION: Low-dose radiotherapy|DRUG: Hydroxychloroquine Sulfate|DRUG: Ritonavir/lopinavir|DRUG: Tocilizumab Injection [Actemra]|DRUG: Azithromycin|DRUG: Corticosteroid|DRUG: Low molecular weight heparin|DEVICE: Oxygen supply
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Risk of Bleeding After Removal of Large Colorectal Polyps in Patients Taking Aspirin
Status: UNKNOWN
Conditions: Gastrointestinal Hemorrhage
Interventions: DRUG: Aspirin (ASA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Exercise on Synaptic Plasticity in Individuals With Mild Cognitive Impairment and in Healthy Aging.
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Self- determined Intensity Interval Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: GPL in Patients With Relapsed/Refractory Diffuse Large B Cell Lymphoma
Status: RECRUITING
Conditions: Relapsed/Refractory Diffuse Large B Cell Lymphoma
Interventions: DRUG: Glofitamab, Poseltinib, Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation (TMS) for Upper Limb Dysfunction in Spinal Cord Injury: a Feasibility Study
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Transcranial Magnetic Stimulation using iTBS Paradigm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Durvalumab With or Without Tremelimumab in Advanced Incurable Solid Malignancies Given With or Without Standard Chemotherapy Regimens
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Malignancies
Interventions: DRUG: durvalumab|DRUG: tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Investigate Aqueous Humor and Multimodal Imaging Biomarkers in Treatment-Naïve Participants With Diabetic Macular Edema Treated With Faricimab
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Faricimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Pravastatin and Rosuvastatin on Coronary Plaques in Patients With Stable Angina Pectoris
Status: UNKNOWN
Conditions: Coronary Disease|Hypercholesterolemia
Interventions: DRUG: pravastatin, rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD.
Status: WITHDRAWN
Conditions: Post Traumatic Stress Disorder
Interventions: DRUG: MDMA|DRUG: Niacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic Study of Axitinib in Patients With Advanced Solid Malignancies
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: AG-013736|DRUG: AG-013736
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Different Feeding Strategies During Packed Red Cell Transfusion on Intestinal Oxygenation
Status: UNKNOWN
Conditions: Necrotizing Enterocolitis
Interventions: DEVICE: NIRS (near-infrared spectroscopy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Integration of Neuromuscular Inhibition Technique On Trapezius Trigger Points.
Status: COMPLETED
Conditions: Myofascial Trigger Point Pain
Interventions: OTHER: Integrated Neuromuscular Inhibition technique|OTHER: Ischemic Compression,Hotpack,TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Long-Term Safety of Desvenlafaxine Succinate Sustained-Release (DVS SR) in Subjects With Pain Associated With Diabetic Peripheral Neuropathy
Status: TERMINATED
Conditions: Diabetic Neuropathy, Painful
Interventions: DRUG: Desvenlafaxine Succinate Sustained-Release (DVS SR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Confirmatory Study of Fentanyl in Participants With Osteoarthritis or Low Back Pain
Status: COMPLETED
Conditions: Chronic Pain|Osteoarthritis|Low Back Pain
Interventions: DRUG: Fentanyl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of BL-B01D1 in Patients With Multiple Solid Tumors, Including Recurrent or Metastatic Gynecological Malignancies
Status: RECRUITING
Conditions: Gynecological Malignant Tumor|Solid Tumor
Interventions: DRUG: BL-B01D1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Cerebral Function in Patients With Chronic Hepatitis C Infection (HCV/CNS)
Status: COMPLETED
Conditions: Hepatitis C, Chronic|Cognition Disorders|Fatigue Syndrome, Chronic|Major Depressive Disorder
Interventions: DRUG: Interferon and ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Preoperative Enteral Immunonutrition for Esophageal Cancer Patients Given Neoadjuvant Chemoradiotherapy
Status: RECRUITING
Conditions: Esophageal Neoplasms
Interventions: DIETARY_SUPPLEMENT: Preoperative immunonutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of SPD503 in Treating ADHD in Children and Adolescents Aged 6-17
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: SPD503 (1 mg)|DRUG: SPD503 (2 mg)|DRUG: SPD503 (3 mg)|DRUG: SPD503 (4 mg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Forced Oscillation Technique (FOT) in Abolishing Flow Limitation
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Respironics Synchrony ventilator (Non Invasive Ventilation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Glycemic Profile of People Suffering From Compulsive Eating Disorders Aiming to Offer an Innovative Nutritional Approach (GLUCOPULSE)
Status: UNKNOWN
Conditions: Bulimia|Binge Eating|Blood Glucose, Low|Crisis State|Compulsion
Interventions: BEHAVIORAL: Eating Behavior|BIOLOGICAL: Blood glucose records
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Branch Chain Amino Acid Therapy on Sarcopenia in Children With Chronic Liver Disease.
Status: UNKNOWN
Conditions: Sarcopenia|Cirrhosis, Liver
Interventions: DIETARY_SUPPLEMENT: branch chain amino acid|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultra-protective Ventilation Monitored by Electrical Impedance Tomography in Patients With Severe Acute Respiratory Distress Syndrome on Veno-venous ECMO
Status: RECRUITING
Conditions: Severe ARDS
Interventions: DEVICE: Ultra-protective mechanical ventilation monitored by electrical impedance tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Milademetan in Combination With Atezolizumab in Patients With Advanced Solid Tumors With CDKN2A Loss
Status: WITHDRAWN
Conditions: Advanced Solid Tumor|CDKN2A|NSCLC|Urothelial Carcinoma Bladder|Melanoma|Pancreas Adenocarcinoma|HNSCC|Renal Cell Carcinoma|Mesothelioma|Gastric Cancer
Interventions: DRUG: Milademetan|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study Evaluating Intranasal GSK256066 and Azelastine Hydrochloride in Subjects With Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis|Rhinitis, Allergic, Seasonal
Interventions: DRUG: GSK256066|DRUG: azelastine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Single Port Laparoscopic Appendectomy in Acute Appendicitis
Status: COMPLETED
Conditions: Appendicitis
Interventions: PROCEDURE: Single port laparoscopic appendectomy|PROCEDURE: 3 port laparoscopic appendectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Intrathecal and Intravenous Dexmedetomidine
Status: COMPLETED
Conditions: Postoperative Analgesia
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Investigate How The Body Handles Multiple Doses Of PF-0243873 And To Investigate The Effect Of PF-02413873 On Sex Hormone Levels In Healthy Young Women
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: PF-02413873 100 mg QD|DRUG: PF-02413873 1500 mg QD|DRUG: PF-02413873 20 mg QD|DRUG: PF-02413873 500 mg QD|DRUG: PF-02413873 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: 68Ga-RM2 PET/MRI in Biochemically Recurrent Prostate Cancer
Status: COMPLETED
Conditions: Prostate Adenocarcinoma
Interventions: DRUG: 68Ga-RM2|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pivotal Study of the Bioequivalence of Oral Viagra® and a Test Sublingual Sildenafil Wafer
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Sublingual Sildenafil|DRUG: Oral Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Active Treatment Study to Induce Clinical Response and/or Remission With GSK1605786A in Subjects With Crohn's Disease
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DRUG: GSK1605786A|DRUG: GSK1605786A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety of a Single Intravenous (IV) Dose of Orbactiv (Oritavancin) in Participants on Chronic Warfarin Therapy Being Treated For Acute Bacterial Skin and Skin Structure Infection (ABSSSI)
Status: COMPLETED
Conditions: Acute Bacterial Skin and Skin Structure Infection
Interventions: DRUG: Oritavancin|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tubal Flushing Using Water Soluble Media for Unexplained Infertility
Status: UNKNOWN
Conditions: Infertility
Interventions: PROCEDURE: Tubal flushing by Urografin®|DRUG: Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Feasibility of Speech Phenotyping for Remote Assessment of Neurodegenerative and Psychiatric Disorders
Status: COMPLETED
Conditions: Alzheimer Disease|Mild Cognitive Impairment|Dementia With Lewy Bodies|Dementia, Vascular|Frontotemporal Dementia|Primary Progressive Aphasia|Parkinson Disease|Motor Neuron Disease|Major Depressive Disorder|Bipolar Disorder|Amyotrophic Lateral Sclerosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: From Cars to Bikes - the Feasibility and Effect of Bicycling for Transportation Among Parents of Toddlers
Status: COMPLETED
Conditions: Bicycling Distance|Bicycling Time|Physical Activity Level|Cardiorespratory Fitness|Body Composition
Interventions: BEHAVIORAL: Access to an e-bicycle with trailer|BEHAVIORAL: Access to a longtail bicycle|BEHAVIORAL: Access to a traditional bike with trailer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect and Efficacy of Onyx™, Zotarolimus-eluting Stent for Coronary Atherosclerosis
Status: UNKNOWN
Conditions: Coronary Artery Disease|Acute Coronary Syndrome|Myocardial Infarction|Angina Pectoris
Interventions: DEVICE: Resolute Onyx
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of MK0594 in Patients With Alcohol Dependence (0594-020)
Status: TERMINATED
Conditions: Alcohol Dependence
Interventions: DRUG: Comparator: MK0594 5 mg/day|DRUG: Comparator: MK0594 1 mg/day|DRUG: Comparator: MK0594 1 mg/week|DRUG: Comparator: Placebo to MK0594
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Usual Vitamin D Supplementation and Its Impact on Children and Adolescents Calciuria.
Status: COMPLETED
Conditions: Chronic Kidney Disease|Renal Transplantation|Nephrotic Syndrome
Interventions: DRUG: Cholecalciferol vial (100 000 UI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CyberKnife Radiosurgical Treatment of Inoperable Early Stage Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: RADIATION: CyberKnife Stereotactic Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Docetaxel in Treating Patients With Recurrent or Persistent Uterine Cancer
Status: COMPLETED
Conditions: Recurrent Uterine Corpus Sarcoma|Uterine Carcinosarcoma
Interventions: DRUG: Gemcitabine Hydrochloride|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ascending Multiple Doses of Oral Surotomycin in Healthy Participants (MK-4261-009)
Status: COMPLETED
Conditions: Clostridium Difficile Associated Diarrhea (CDAD)
Interventions: DRUG: Surotomycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lung Immune Challenge Study: Controlled Exposure to Inhaled Resiquimod (R848)
Status: RECRUITING
Conditions: Innate Immunity|Mucosal Immunity|Asthma|Viral Infection
Interventions: DRUG: R848|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Different Use of The Aerosol Box in COVID-19 Patients; Internal Jugular Vein Cannulation
Status: COMPLETED
Conditions: COVID-19 Pneumonia
Interventions: PROCEDURE: Internal jugular vein cannulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Fasting Study of Metformin Hydrochloride ER Tablets 750 mg and Glucophage® XR Tablets 750 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Metformin Hydrochloride ER Tablets 750 mg|DRUG: Glucophage® XR Tablets 750 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bright Light Therapy for Treatment of Sleep Problems Following Mild Traumatic Brain Injury
Status: COMPLETED
Conditions: Concussion, Mild|Post-Concussion Symptoms|Sleep Problems
Interventions: DEVICE: mTBI wavelength-1 bright light|DEVICE: mTBI wavelength-2 bright light|DEVICE: HC wavelength-1 bright light|DEVICE: HC wavelength-2 bright light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Sunitinib in Treating Patients With Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: sunitinib malate|BIOLOGICAL: bevacizumab|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Japan Phase I/II Study of Bortezomib in Relapsed or Refractory Multiple Myeloma Patients
Status: COMPLETED
Conditions: Refractory|Multiple Myeloma|Relapse
Interventions: DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multidisciplinary Intervention Including a Clinical Decision Support System and an App for Drug Therapy Management in Older Patients
Status: UNKNOWN
Conditions: Polypharmacy|Multimorbidity|Aged
Interventions: OTHER: Multidisciplinary Approach Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Procalcitonin-Guided Antibiotic Therapy in Bronchiectasis
Status: COMPLETED
Conditions: Procalcitonin|Bronchiectasis|Antibiotic Therapy
Interventions: OTHER: Procalcitonin|OTHER: Clinical Experience
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resiliency Training for Patients With NF2 Via Videoconferencing With Skype
Status: COMPLETED
Conditions: Neurofibromatosis 2
Interventions: BEHAVIORAL: Stress Management Group 1|BEHAVIORAL: Stress Management Group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Erdosteine (Erdotin) Versus Standard Care Plus Placebo on Erdosteine for Treatment of Cough in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)
Status: WITHDRAWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Erdosteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Steroid Withdrawal in Pediatric Renal Transplant Recipients Under Cyclosporine (CyA) and Mycophenolate Mofetil (MMF)
Status: COMPLETED
Conditions: Kidney Diseases
Interventions: DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The SOLID Platelet Study
Status: RECRUITING
Conditions: Platelet Transfusion Refractoriness (PTR)|Thrombocytopenia
Interventions: OTHER: Platelet Transfusion - LONG Platelet Transfusion|OTHER: Platelet Transfusion - SHORT Platelet Transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Erectile Dysfunction II
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Udenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Methodologies for Assessing Glucose-Dependent Insulin Secretion (0000-104)(COMPLETED)
Status: COMPLETED
Conditions: The Methodology Assessment of Glucose Dependent Insulin Secretion
Interventions: DRUG: Comparator: exenatide|DRUG: Comparator: exenatide|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects Of CP-690,550 (Tasocitinib) On Cholesterol Metabolism In Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: CP-690,550 (tasocitinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Examining the Health Effects of iTHRIVE 365 Among Black Same Gender Loving Men
Status: NOT_YET_RECRUITING
Conditions: Sexual and Gender Minorities|Social Stigma|Medication Adherence|Depressive Symptoms|Anxiety Symptoms
Interventions: BEHAVIORAL: iTHRIVE 365 HIV care intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rivaroxaban for Treatment in Venous or Arterial Thrombosis in Neonates
Status: COMPLETED
Conditions: Thromboembolism
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Gemcitabine and Nab-Paclitaxel vs Gemcitabine, Nab-Paclitaxel, Durvalumab and Tremelimumab as 1st Line Therapy in Metastatic Pancreatic Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Gemcitabine|DRUG: Nab-paclitaxel|DRUG: Durvalumab|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bovine Colostrum for Patients With Non Alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis|Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: Bovine colostrum powder
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Urge Urinary Incontinence in Women After Failure of Cesa or Vasa
Status: UNKNOWN
Conditions: Surgical Treatment of Urge Incontinence
Interventions: PROCEDURE: TOT|DRUG: solifenacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evidence Generation Related to Stunting Prevention in Balochistan
Status: COMPLETED
Conditions: Stunting|Low Birth Weight|Anemia in Pregnancy
Interventions: DIETARY_SUPPLEMENT: Maamta (Nutritious Food Supplement)|DIETARY_SUPPLEMENT: Wawamum (Lipid-Based Nutrient Supplement)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tranexamic Acid Dosage for Topical Treatment of Anterior Epistaxis
Status: COMPLETED
Conditions: Anterior Epistaxis|Tranexamic Acid
Interventions: DRUG: Tranexamic acid|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Treatments for Cognitive Impairment in Older Adults
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Probable Alzheimer's Disease
Interventions: OTHER: Modified Atkins Diet|OTHER: NIA Diet for Seniors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Rocuronium on the Response of Composite Variability Index (CVI) to Laryngoscopy
Status: UNKNOWN
Conditions: Laryngoscopy
Interventions: DRUG: remifentanil infusion|DRUG: rocuronium dose + remifentanil infusion|DRUG: rocuronium dose + remifentanil infusion|DRUG: remifentanil infusion|DRUG: rocuronium dose + remifentanil infusion|DRUG: rocuronium dose + remifentanil infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE