pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Light Treatment for Sleep/Wake Disturbances in Alzheimer's Disease
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: DEVICE: Bright light|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maintaining Patency in BioFlo Implanted Port Catheters With Saline Only Flushes
Status: TERMINATED
Conditions: Obstruction; Catheter, Infusion Catheter (Vascular)|Catheter; Complications (Indwelling Catheter)
Interventions: OTHER: Heparinized saline catheter flush|DRUG: Saline-only catheter flush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Comparison of Sedation/Analgesia & LMA on Anxiety Level and Patient Satisfaction in In-Vitro Fertilization
Status: COMPLETED
Conditions: Anesthesia|In-vitro Fertilization|Analgesia
Interventions: DIAGNOSTIC_TEST: State-Trait Anxiety Inventory|DIAGNOSTIC_TEST: Quality of Recovery Score|OTHER: Sedation/Analgesia|DEVICE: Laryngeal Mask Airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Effect of Empagliflozin on Podocyte Specific Proteins in African American Veterans With NDKD
Status: RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Relative Bioavailability of a New Formulation Compared With the Approved Formulation of rhPTH [1-84] and to Find Out Dose Linearity of the New Formulation in Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: rhPTH(1-84)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Adaptive Radiation Therapy in Pre-operative or Exclusive Radiation Therapy for Limb Soft Tissues Sarcomas
Status: UNKNOWN
Conditions: Sarcoma, Soft Tissue
Interventions: RADIATION: Adaptive radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Trial to Evaluate Belzupacap Sarotalocan (AU-011) Via Suprachoroidal Administration in Subjects With Primary Indeterminate Lesions and Small Choroidal Melanoma
Status: COMPLETED
Conditions: Uveal Melanoma|Ocular Melanoma|Choroidal Melanoma
Interventions: DRUG: AU-011|DEVICE: Suprachoroidal Microinjector|DEVICE: PDT Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells Delivered Intraperitoneally for the Management of Platinum Resistant Ovarian Cancer, Mesonephric-like Adenocarcinoma, and Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer|Ovarian Cancer|Adenocarcinoma
Interventions: DRUG: TROP2-CAR-NK|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Patient Experience: BMBA
Status: ACTIVE_NOT_RECRUITING
Conditions: Bone Marrow Cancer|Leukemia|Lymphoma|Multiple Myeloma|Hematologic Cancer
Interventions: OTHER: Virtual reality|OTHER: Environmental changes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-invasive Brain Stimulation to Enhance Treatment of Dysarthria Post-stroke
Status: COMPLETED
Conditions: Dysarthria|Stroke
Interventions: DEVICE: tDCS active|DEVICE: tDCS sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Belimumab Administered Subcutaneously to Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Single Dose Group: Belimumab IV 240 mg|BIOLOGICAL: Single Dose Group: Belimumab SC 2 x 120 mg|BIOLOGICAL: Single Dose Group: Belimumab SC 1 x 240 mg|BIOLOGICAL: Single Dose Group: Belimumab SC 1 x 200 mg|BIOLOGICAL: Multiple Dose Group: Belimumab SC 2 x 120 mg weekly|BIOLOGICAL: Multiple Dose Group: Belimumab SC 1 x 200 mg weekly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amino Acid Supplementation in Recovery From Severe Burns
Status: COMPLETED
Conditions: Burn Injury
Interventions: DIETARY_SUPPLEMENT: EAA Supplementation + Exercise Training|DIETARY_SUPPLEMENT: Placebo + Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pembrolizumab and Ruxolitinib Phosphate in Treating Patients With Metastatic Stage IV Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Metastatic Malignant Neoplasm in the Bone|Stage IV Breast Cancer AJCC v6 and v7|Triple-Negative Breast Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab|DRUG: Ruxolitinib Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of 68Ga-labeled ACE2 Targeting Probe PET/CT Imaging in Tracing ACE2 Expression and Diagnosis of Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer|Healthy Human
Interventions: DRUG: 68Ga-A3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial Looking at Ofatumumab for People With Chronic Lymphocytic Leukaemia Who Cannot Have More Intensive Treatment
Status: UNKNOWN
Conditions: Chronic Lymphocytic Leukaemia
Interventions: DRUG: Ofatumumab|DRUG: Chlorambucil|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Sclerotherapy Agents Used for Rectal Prolapse Treatment in Children
Status: COMPLETED
Conditions: Rectal Prolapse
Interventions: PROCEDURE: injection 5% phenol in almond oil|PROCEDURE: injection 15% hypertonic saline|PROCEDURE: injection 50% dextrose water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-help Treatment for Insomnia in Breast Cancer Patients
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: professionally administered cognitive-behavioral therapy|BEHAVIORAL: self-administered form of cognitive-behavioral therapy|BEHAVIORAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Bupivacaine Induced Motor Blockade During the Second Stage of Labor
Status: COMPLETED
Conditions: Pregnancy
Interventions: DRUG: Epidural Bupivacaine plus fentanyl|DRUG: Epidural fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma|Gliosarcoma|MGMT-Unmethylated Glioblastoma
Interventions: RADIATION: Radiation Therapy|DRUG: Tinostamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral and Swallowing Function in Older Adults
Status: RECRUITING
Conditions: Oropharyngeal Dysphagia
Interventions: DIAGNOSTIC_TEST: 3-ounce water swallow test|DIAGNOSTIC_TEST: Kayser-Jones Brief Oral Health Status Examination (BOHSE)|DIAGNOSTIC_TEST: Tongue pressure|DIAGNOSTIC_TEST: Test of Masticating and Swallowing Solids (TOMASS)|DIAGNOSTIC_TEST: Respiratory function tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effectiveness of Flash Glucose Monitoring System on Glycemic Control in Patients With New-onset Type 2 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Flash Glucose Monitoring
Interventions: DEVICE: Flash Glucose Monitoring System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating and Comparing Single Dose and Multiple Dose Pharmacokinetics of ER OROS Paliperidone in Healthy Japanese and Caucasian Adults.
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone ER OROS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Intraocular Pressure Measurement by Tomometer and Anterior Chamber Depth Measurement by Ultrasound
Status: TERMINATED
Conditions: Urological Cancer|Gastrointestinal Cancer|Malignant Female Reproductive System Neoplasm
Interventions: DEVICE: IOP by tonometer|DEVICE: Anterior chamber depth measurement by ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Photodynamic Therapy (PDT) in Patients With Central Serous Chorioretinopathy (CSC)
Status: COMPLETED
Conditions: Central Serous Chorioretinopathy
Interventions: PROCEDURE: PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epacadostat Before Surgery in Treating Patients With Newly Diagnosed Stage III-IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage III Fallopian Tube Cancer AJCC v7|Stage III Ovarian Cancer AJCC v6 and v7|Stage III Primary Peritoneal Cancer AJCC v7|Stage IIIA Fallopian Tube Cancer AJCC v7|Stage IIIA Ovarian Cancer AJCC v6 and v7|Stage IIIA Primary Peritoneal Cancer AJCC v7|Stage IIIB Fallopian Tube Cancer AJCC v7|Stage IIIB Ovarian Cancer AJCC v6 and v7|Stage IIIB Primary Peritoneal Cancer AJCC v7|Stage IIIC Fallopian Tube Cancer AJCC v7|Stage IIIC Ovarian Cancer AJCC v6 and v7|Stage IIIC Primary Peritoneal Cancer AJCC v7|Stage IV Fallopian Tube Cancer AJCC v6 and v7|Stage IV Ovarian Cancer AJCC v6 and v7|Stage IV Primary Peritoneal Cancer AJCC v7
Interventions: DRUG: Epacadostat|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study on the Effect of Eurartesim™ on QT/QTc Interval Compared to Riamet in Healthy Volunteers
Status: COMPLETED
Conditions: Malaria, Falciparum
Interventions: DRUG: Eurartesim™|DRUG: Riamet®|OTHER: Placebo and finally Moxifloxacin|DRUG: Eurartesim™|DRUG: Eurartesim™|OTHER: Placebo and finally Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hormone Therapy and Intensity-Modulated Radiation Therapy in Treating Patients With Metastatic Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: PSA Level Greater Than Two|Stage IV Prostate Adenocarcinoma AJCC v7
Interventions: DRUG: Bicalutamide|DRUG: Goserelin Acetate|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|DRUG: Leuprolide Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Resolution Manometry for Swallowing
Status: TERMINATED
Conditions: Motility Disorder
Interventions: PROCEDURE: esophageal manometry|DIETARY_SUPPLEMENT: Gatorade|OTHER: Supine position|OTHER: Semi-recumbent position|PROCEDURE: Sitting|PROCEDURE: Standing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Bee Venom Phonophoresis on Healing of Chronic Lower Limb Ulcers
Status: COMPLETED
Conditions: Ulcer, Leg
Interventions: COMBINATION_PRODUCT: Bee venom phonophoresis|DEVICE: low intensity ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Modulating Exercise Dosage to Improve Concussion Recovery
Status: RECRUITING
Conditions: Concussion, Brain|Treatment|Aerobic Exercise|Inflammation|Depression, Anxiety
Interventions: BEHAVIORAL: High Dose Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation for Extremely Preterm Infants
Status: COMPLETED
Conditions: Vitamin D Deficiency|Preterm Infants|Bronchopulmonary Dysplasia
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol|DIETARY_SUPPLEMENT: Cholecalciferol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cabozantinib-S-Malate in Treating Patients With Recurrent or Progressive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Clear Cell Adenocarcinoma|Ovarian Clear Cell Adenocarcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: DRUG: Cabozantinib S-malate|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of MT-401 in Patients With AML Following Stem Cell Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Stem Cell Transplantation
Interventions: DRUG: MT-401
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Evaluating Outcomes of Self-Fit and Professionally Fit Hearing Aids
Status: RECRUITING
Conditions: Hearing Loss
Interventions: DEVICE: Comparison of PRO-FIT or SELF-FIT fitting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmaceutical Treatment of Fatigue After Aneurysmal Subarachnoid Hemorrhage
Status: COMPLETED
Conditions: Aneurysmal Subarachnoid Hemorrhage
Interventions: DRUG: OSU 6162|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ISIS 2302-CS27, A 6-Week, Placebo-Controlled Clinical Study to Evaluate the Effectiveness of Alicaforsen (ISIS 2302) in Patients With Mild to Moderate Active Ulcerative Colitis.
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Alicaforsen
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy
Status: RECRUITING
Conditions: Fanconi Anemia|Severe Marrow Failure|Myelodysplastic Syndrome (MDS)|Acute Myelogenous Leukemia (AML)
Interventions: DRUG: Busulfan|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: rabbit ATG|DRUG: G-CSF|BIOLOGICAL: Peripheral blood stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Granisetron Versus Ondansetron: Comparative Effects on ECG, QTc
Status: COMPLETED
Conditions: Prolonged QTc Interval
Interventions: DRUG: Ondansetron|DRUG: Granisetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Human Hookworm Candidate Vaccine With or Without Additional Adjuvant in Brazilian Adults
Status: COMPLETED
Conditions: Hookworm Infection|Hookworm Disease
Interventions: BIOLOGICAL: 10 μg Na-GST-1/Alhydrogel|BIOLOGICAL: 30 μg Na-GST-1/Alhydrogel|BIOLOGICAL: 100 μg Na-GST-1/Alhydrogel|BIOLOGICAL: 10 μg Na-GST-1/ Alhydrogel/GLA-AF|BIOLOGICAL: 30 μg Na-GST-1/Alhydrogel/GLA-AF|BIOLOGICAL: 100 μg Na-GST-1/Alhydrogel/GLA-AF|BIOLOGICAL: Butang® hepatitis B vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Novel Approach to Optimize Programmed Intermittent Epidural Bolus (PIEB) Delivery for Labour Analgesia
Status: COMPLETED
Conditions: Labor Pain
Interventions: OTHER: Coordinate A|OTHER: Coordinate B|OTHER: Coordinate C|OTHER: Coordinate D|OTHER: Coordinate E|OTHER: Coordinate F|OTHER: Coordinate G|OTHER: Coordinate H|OTHER: Coordinate I|OTHER: Coordinate J|OTHER: Coordinate K|OTHER: Coordinate L|OTHER: Coordinate M|OTHER: Coordinate N
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardioverter Defibrillator Replacement With Induction of Ventricular Fibrillation and Defibrillation Testing
Status: UNKNOWN
Conditions: Defibrillation Capacity of Defibrilators After Replacement
Interventions: PROCEDURE: Defibrillation testing during ICD replacement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PrEssure wiRe Compared to Microcatheter-based Sensing Technology For the Evaluation of FFR Measurements
Status: COMPLETED
Conditions: Ischemia|Angina
Interventions: DEVICE: St. Jude Medical Pressure Wire|DEVICE: ACIST Navvus Microcatheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility of a New Silicone Hydrogel Lens
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Investigational contact lens|DEVICE: Acuvue Oasys Contact Lens|DEVICE: Air Optix Aqua
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Safety, Tolerability and Efficacy of the Depigmented Modified Allergen Extract of Two Mites in Subjects With Allergic Rhinitis or Rhinoconjunctivitis, With Controlled Allergic Asthma
Status: COMPLETED
Conditions: Rhinitis|Rhinoconjunctivitis|Asthma
Interventions: BIOLOGICAL: DP/MG/14-1|BIOLOGICAL: DP/MG/14-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pan-tumor Neoadjuvant Basket Study of Immune Check-point Inhibition and Novel Immuno-oncology Combinations
Status: RECRUITING
Conditions: Resectable MMR-deficient Solid Tumors|Resectable MMR-proficient Solid Tumors
Interventions: DRUG: botensilimab|DRUG: balstilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of CD19 CAR T Cells Using CliniMACS Prodigy for Relapsed/Refractory CD19 Positive ALL and NHL
Status: NOT_YET_RECRUITING
Conditions: Acute Lymphoblastic Leukemia, in Relapse|Non-Hodgkin's Lymphoma, Relapsed|Non-Hodgkin's Lymphoma Refractory|Acute Lymphoblastic Leukemia With Failed Remission|B-cell Non Hodgkin Lymphoma|B Cell Leukemia
Interventions: BIOLOGICAL: CD19 specific Chimeric Antigen Receptor T Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Probiotics on Symptoms of Upper Respiratory Tract Infections
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Lactobacillus acidophilus NCFM|DIETARY_SUPPLEMENT: Combination of Lactobacillus acidophilus and Bifidobacterium lactis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Beneficial Effects of Eplerenone on Central Serous Chorioretinopathy
Status: UNKNOWN
Conditions: Central Serous Chorioretinopathy
Interventions: DRUG: Eplerenone|DRUG: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of HER2 Tumor Vaccine in Patients With Her-2 Positive Gastric/GEJ Adenocarcinoma Esophagogastric
Status: UNKNOWN
Conditions: Adenocarcinoma - GEJ|Adenocarcinoma of the Stomach
Interventions: BIOLOGICAL: HER2 Tumor Vaccine|BIOLOGICAL: HER2 Tumor Vaccine+ Standard of Care chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Lid Technique Versus Standard Technique for Treatment of Mandibular Lesions
Status: COMPLETED
Conditions: Mandible Cyst|Mandible Tumor|Mandibular Diseases
Interventions: DEVICE: bone lid technique|DEVICE: standard technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: UROGEN WELL D-ONE : Evaluation of a Novel Diagnostic for Sexually Transmitted Bacterial Infections
Status: COMPLETED
Conditions: Sexually Transmitted Diseases, Bacterial|Bacterial Urinary Tract Infection|Antimicrobial Resistance
Interventions: OTHER: No intervention. This study was an evalution with no intervention.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Systematic Assessment and Targeted Improvement of Services Following Yearlong Surgical Outcomes Surveys
Status: COMPLETED
Conditions: Heart Attack|Cardiac Arrest|Congestive Heart Failure|Atrial Fibrillation|Angina|Deep Vein Thrombosis|Pulmonary Embolism|Respiratory Arrest|Respiratory Failure|Pneumonia|Gastrointestinal Bleed|Stomach Ulcer|Delirium|Stroke|Nerve Injury|Surgical Wound Infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preventing Cognitive Decline: The CITA GO-ON Multi-domain Intervention Study
Status: ENROLLING_BY_INVITATION
Conditions: Dementia|Cognitive Decline|Prevention|Life Style|Risk Factor, Cardiovascular|Diet Habit|Cognitive Intervention|Behavioral Intervention
Interventions: BEHAVIORAL: Multimodal intervention (MM-int)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of High Dose Fish Oil Supplementation After Recent Heart Attack Using Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Myocardial Infarction|Death, Sudden, Cardiac
Interventions: DRUG: Omega-3 Fatty Acids (Fish Oil Supplements)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Breast Milk Simulated Infant Formula
Status: COMPLETED
Conditions: Infant Formula|Breast Milk
Interventions: OTHER: Breast milk|OTHER: Kieember Infant formula, Ruibuen®|OTHER: Yashili Infant formula, Ruibuen®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Using Artificial Intelligence-platform on Plaque Control and Periodontal Treatment Outcome in Patients With Periodontal Disease-Preliminary Results
Status: UNKNOWN
Conditions: Periodontal Diseases
Interventions: DEVICE: Dental monitoring (DM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Massage, Wipe Bathing and Tub Bathing on Physiological Measurements of Late Premature Newborns
Status: COMPLETED
Conditions: Premature Newborn|Nurse|Physiological Measurements
Interventions: OTHER: Control|OTHER: Massage|OTHER: Sponge Bathing|OTHER: Tub Bathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Interpretation of Health News Items Reporting Results of Phase I/II (Non-randomized) Trials With or Without Spin by French-speaking Population
Status: WITHDRAWN
Conditions: The Study Focus on no Specific Condition
Interventions: OTHER: News items with spin|OTHER: News items without spin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Comparison of Conventional Versus 3-D Printed Complete Denture Regarding Retention, Accuracy, Elctromyographic Activity and Patient Satisfaction.
Status: COMPLETED
Conditions: Edentulous Mouth
Interventions: OTHER: 3D Printed Complete Dentures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Targeted Neurocognitive Training (TNT) Study
Status: SUSPENDED
Conditions: HIV|Aging|Cognitive Function Abnormal|Cognitive Training|Older Adults
Interventions: BEHAVIORAL: Targeted Neurocognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of YH14618 in Patients With Degenerative Disc Disease
Status: COMPLETED
Conditions: Degenerative Disc Disease
Interventions: DRUG: YH14618|DRUG: YH14618|DRUG: YH14618|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Long-term Persistence of Immunity to Hepatitis B, in Adolescents Vaccinated in Infancy With Engerix™-B Kinder
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: Engerix™-B Kinder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Laparoscopic Narrow Band Imaging for Detection of Occult Cancer Metastases
Status: COMPLETED
Conditions: Gastrointestinal and Gynecologic Malignancies
Interventions: DEVICE: Laparoscopic narrow band imaging|DEVICE: Standard white-light laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Ultrasonographic and Clinical Features of Different Energy Levels Extracorporeal Shock Wave Therapy in Plantar Fasciitis
Status: UNKNOWN
Conditions: Extracorporeal Shock Wave Therapy
Interventions: DEVICE: Extracorporeal Shock Wave Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Site and Mechanism(s) of Expiratory Airflow Limitation in COPD, Emphysema and Asthma-COPD Overlap
Status: RECRUITING
Conditions: COPD, Emphysema, Asthma COPD Overlap|Emphysema
Interventions: OTHER: As above: diagnosis: COPD, Emphysema, Asthma-COPD Overlap
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Paired-pulse rTMS Treatment for Methamphetamine Use Disorder Based on the Frontopolar-Cerebellum
Status: RECRUITING
Conditions: Amphetamine Use Disorders
Interventions: DEVICE: 10Hz rTMS based on cerebellum and FPC|DEVICE: 10Hz rTMS based on cerebellum or FPC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Folic Acid and Vitamin B12 in Young Indian Children
Status: COMPLETED
Conditions: Diarrhea|Pneumonia
Interventions: DIETARY_SUPPLEMENT: Folic Acid|DIETARY_SUPPLEMENT: Vitamin B12|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Folic acid and vitamin B12
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reducing the Residual Reservoir of HIV-1 Infected Cells in Patients Receiving Antiretroviral Therapy
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Panobinostat|DRUG: Pegylated Interferon-alpha2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FMT in IT-refractory HCC - FAB-HCC Pilot Study
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: COMBINATION_PRODUCT: FMT combined with Atezolizumab plus Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhaled Amikacin Treatment for Nontuberculous Mycobacterial Lung Disease
Status: WITHDRAWN
Conditions: Pulmonary Non-tuberculous Mycobacterial Lung Disease
Interventions: DRUG: Amikacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of a Prokinetic Agent as an Adjunct to Thrice Weekly Bowel Care After SCI
Status: COMPLETED
Conditions: Spinal Cord Injuries|Constipation|Neurogenic Bowel
Interventions: DRUG: Neostigmine and Glycopyrrolate|DEVICE: Iontophoresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomised Study for Use of CHG Dressing at Entry Site of EVD's to Reduce EVD-associated Infections
Status: COMPLETED
Conditions: Wound Contamination
Interventions: DEVICE: 3M™ Tegaderm™ CHG I.V. Securement Dressing|DEVICE: Placebo Comparator: 3M™ Tegaderm™ I.V. Advanced Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: BT1718 in Patients With Advanced Solid Tumours.
Status: COMPLETED
Conditions: Advanced Solid Tumours|Non-Small Cell Lung Cancer|Non-Small Cell Lung Sarcoma|Oesophageal Cancer
Interventions: DRUG: BT1718
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetics of Appendix Cancer Study
Status: RECRUITING
Conditions: Appendix Cancer|Appendiceal Cancer|Appendiceal Neoplasms|Appendiceal Mucinous Neoplasm|Appendiceal Adenocarcinoma|Appendiceal Carcinoid Tumor|Appendiceal Neoplasm Malignant Secondary|Appendix Adenocarcinoma|Appendix Mucinous Neoplasm|Appendix Tumor|Appendix Cancer Metastatic|Appendix NET|Low-Grade Appendix Mucinous Neoplasm|High Grade Appendix Mucinous Neoplasm|High Grade Appendix Mucinous Adenocarcinoma
Interventions: GENETIC: Genetic profiling|OTHER: Retrospective tissue procurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Routine Physical Therapy With and Without Neurodevelopmental Technique on GMF, Spasticity and HRQOL in Diplegic CP
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Routine Physical therapy with Neurodevelopmental technique|OTHER: Routine Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Tranexamic Acid in the Treatment of Symptomatic Subdural Hematoma
Status: NOT_YET_RECRUITING
Conditions: Subdural Hematoma
Interventions: DRUG: Tranexamic acid (TXA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing ELUVIA Versus Bare Metal Stent in Treatment of Superficial Femoral and/or Proximal Popliteal Artery
Status: ACTIVE_NOT_RECRUITING
Conditions: Arterial Occlusive Diseases|Atherosclerosis|Vascular Diseases|Arteriosclerosis
Interventions: DEVICE: Peripheral stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: SGLT2i to Prevent of Liver Complications in Patients With CHB and Diabetes Mellitus
Status: RECRUITING
Conditions: Chronic Hepatitis B
Interventions: DRUG: Dapagliflozin 10mg Tab|DRUG: Placebo 10mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cortical Priming to Optimize Gait Rehabilitation in Stroke: a Renewal
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: Transcranial direct current stimulation (tDCS)|OTHER: Ankle motor training|BEHAVIORAL: High intensity interval speed based treadmill training (HIISTT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of 90Y-SMT487 in Subjects With Symptomatic Malignant Carcinoid Tumors
Status: WITHDRAWN
Conditions: Malignant Carcinoid Tumor
Interventions: DRUG: 90Y-SMT487
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Adaptative, Multidisciplinary, Reach-out Program, Facilitating Pre Exposition HIV Prophylaxis (PrEP) Prescription and Retention in Care, in a Group of Trans Womens (TW) at High Risk of HIV Infection.
Status: NOT_YET_RECRUITING
Conditions: Transgenderism
Interventions: OTHER: Psychosocial assistance|OTHER: Medical care|OTHER: Legal-Administrative Assistance|OTHER: Focus Group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Palbociclib, Trastuzumab,Pyrotinib and Fulvestrant Treatment in Patients With Brain Metastasis From ER/PR Positive, HER-2 Positive Breast Cancer: A Multi-center, Prospective Study in China
Status: RECRUITING
Conditions: Breast Cancer|Brain Metastases
Interventions: DRUG: Palbociclib, Trastuzumab, Pyrotinib and Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protein Sorbent Properties of Montmorillonite in Vitro and in Vivo Models
Status: COMPLETED
Conditions: Urea Cycle Disorders, Inborn|Other Metabolic Diseases
Interventions: DIETARY_SUPPLEMENT: montmorillonite 5 g|DIETARY_SUPPLEMENT: montmorillonite 3 g|DIETARY_SUPPLEMENT: Montmorillonite 1 g
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Endostatin Combined With Docetaxel in the Treatment of Advanced Non-small Cell Lung Cancer Patients
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Endostatins|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Formal Contraception Handouts
Status: TERMINATED
Conditions: Contraception|Counseling
Interventions: OTHER: Contraception Handout|OTHER: Nutritional Handout
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: External Fixator or Antibiotic-coated Plate in Severe Open Long Bone Fractures
Status: NOT_YET_RECRUITING
Conditions: Fracture Related Infection
Interventions: PROCEDURE: antibiotic-coated plate|PROCEDURE: external fixator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Systemic and Local Inflammatory Biomarkers in the Treatment of Refractory Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema|Inflammation
Interventions: DIAGNOSTIC_TEST: serum samples|DRUG: dexamethasone implant versus ranibizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Extension Study of Omalizumab in Participants With Chronic Rhinosinusitis With Nasal Polyps
Status: COMPLETED
Conditions: Nasal Polyps|Chronic Rhinosinusitis
Interventions: DRUG: Omalizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testosterone Therapy in Hypogonadal Men Treated With Opioids
Status: COMPLETED
Conditions: Hypogonadism
Interventions: DRUG: Testosterone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for Integrated Care to Help At Risk Teen (iCHART) Intervention
Status: RECRUITING
Conditions: Suicide and Depression|Adolescent Behavior
Interventions: BEHAVIORAL: iCHART|BEHAVIORAL: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: "Escape" Phenomenon of the Antihypertensive Therapy Efficacy
Status: ACTIVE_NOT_RECRUITING
Conditions: Arterial Hypertension
Interventions: DEVICE: Ambulatory blood pressure measurement device|DEVICE: Sphygmocor|DEVICE: VaSera-VS|DEVICE: Somnocheck
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Pectoralis Block on Analgesia After Simple Mastectomy
Status: WITHDRAWN
Conditions: Mastectomy|Nerve Block|Analgesia, Postoperative
Interventions: PROCEDURE: Pectoralis block|DRUG: Normal saline injection|DRUG: Ropivacaine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adaptation of a Rehabilitation Program for Prosody and Its Application on Egyptian Hearing Impaired Children
Status: COMPLETED
Conditions: Hearing Impaired Children
Interventions: BEHAVIORAL: Prosody treatment program|BEHAVIORAL: Traditional auditory and language rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Effectiveness of Two Anti-HIV Drug Combinations
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Nelfinavir mesylate|DRUG: Lamivudine|DRUG: Stavudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Sugammadex Reversal of Neuromuscular Blockade and Postoperative Bleeding
Status: UNKNOWN
Conditions: Blood Coagulation Tests ( INR, APTT)
Interventions: DRUG: Sugammadex intravenous|DRUG: Intravenous neostigmine and atropine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Pharmacokinetics of Single and Multiple Ascending Doses of 3K3A-APC in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: 3K3A-APC, diluted in 0.9% sodium chloride in water|DRUG: 0.9% NaCl in water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety, Tolerability and Pharmacokinetics Study of L608 in Healthy Adults
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: L608 Liposomal inhalation solution|DRUG: Placebo Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Abdominal Massage and Kegel Exercises on Constipation and Quality of Life in Female Students
Status: NOT_YET_RECRUITING
Conditions: Functional Constipation|Constipation|Quality of Life
Interventions: BEHAVIORAL: Abdominal massage group|BEHAVIORAL: Kegel Exercises group|BEHAVIORAL: Both abdominal massage and kegel exercises to gether
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BPD Saturation TARgeting
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia|Chronic Lung Disease of Prematurity|Chronic Lung Disease
Interventions: OTHER: LOWER oxygen saturation target group|OTHER: HIGHER oxygen saturation target group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Whey Protein Hydrolysate on Human Muscle Protein Synthesis
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Whey Protein Hydrolysate (WPH)|DIETARY_SUPPLEMENT: Intact Whey Protein (WHEY)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: European Deep Brain Stimulation (DBS) Depression Study
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DEVICE: Deep Brain Stimulation|DEVICE: Deep Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sedentary Behavior and Health Outcomes Study
Status: COMPLETED
Conditions: Sedentary Lifestyle|Metabolic Disturbance|Pediatric Obesity|Physical Activity
Interventions: BEHAVIORAL: Walking breaks|BEHAVIORAL: Sitting only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioavailability Study of Five Tablet Formulations of Dabigatran Etexilate Compared to Commercial Capsule Formulation in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dabigatran etexilate tablet E1|DRUG: Dabigatran etexilate tablet D1|DRUG: Dabigatran etexilate tablet C1|DRUG: Dabigatran etexilate tablet B1|DRUG: Dabigatran etexilate tablet A1|DRUG: Dabigatran etexilate capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of OFS Combined With AI Endocrine Therapy in Chinese Premenopausal Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: OFS + Anastrozole|DRUG: OFS + Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evulating DA-302168S Tablets in Overweight/Obese Subjects
Status: NOT_YET_RECRUITING
Conditions: Overweight and Obesity
Interventions: DRUG: DA-302168S|DRUG: Placebo of DA-302168S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TMS Treatment in Multiple System Atrophy With Fatigue
Status: UNKNOWN
Conditions: Transcranial Magnetic Stimulation|Multiple System Atrophy|Fatigue
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Walking With the EksoNR in Stroke Patients and Healthy Controls: Biomechanical Changes and User Experience.
Status: UNKNOWN
Conditions: Stroke|Healthy
Interventions: DEVICE: High Swing Assistance|DEVICE: Neutral Swing Assistance|DEVICE: High Swing Resistance|DEVICE: Max Trajectory Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study With RO4917523 in Patients With Fragile X Syndrome
Status: COMPLETED
Conditions: Fragile X Syndrome
Interventions: DRUG: Placebo (for RO4917523 ascending doses)|DRUG: Placebo (for RO4917523 fixed dose)|DRUG: RO4917523|DRUG: RO4917523
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Oral Malodor and Other Outcomes Following The Use of Two-Step Toothpaste Oral Hygiene
Status: COMPLETED
Conditions: Oral Malodor
Interventions: DRUG: Stannous fluoride toothpaste|DRUG: Potassium nitrate toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intermediate-Dose Cytarabine Induction Regimen in Adult AML
Status: RECRUITING
Conditions: AML
Interventions: DRUG: Daunomycin and Cytarabine (DA Regimen)|DRUG: Daunomycin and Cytarabine (Intermediate Dose of DA Regimen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Glycemic Control After Reperfusion on Acute Kidney Injury in Living Donor Liver Transplantation
Status: COMPLETED
Conditions: Acute Kidney Injury|Hyperglycemia|Hypoglycemia|End Stage Liver Disease
Interventions: OTHER: Observational study, records of blood glucose level after reperfusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Novel Capecitabine Dosing Schedule in Combination With Lapatinib, Based on the Norton-Simon Mathematical Method in Patients With HER2 Overexpressed/Amplified, Trastuzumab (Herceptin) -Refractory, Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: capecitabine, lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quadratus Lumborum Block Type 2 Versus Posterior Transversus Abdominus Plane Block
Status: COMPLETED
Conditions: Regional Block
Interventions: PROCEDURE: Posterior transversus abdominus plane block|PROCEDURE: Quadratus lumborum block type 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION