pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: STRW-T Intervention for Autistic Adolescents in 11th and 12th Grade
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: STRW-T|BEHAVIORAL: PEERS-T
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study of BPS804 Treatment in Adult Patients With Type I, III or IV Osteogenesis Imperfecta
Status: WITHDRAWN
Conditions: Osteogenesis Imperfecta
Interventions: DRUG: BPS804
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment Of Duration Of Action, Safety & Toleration Of UK369,003 and Cialis In Patients With Erectile Dysfunction
Status: COMPLETED
Conditions: Impotence
Interventions: DRUG: UK0369,003|DRUG: Cialis (Tadalafil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Role of Preoperative Immunonutrition on Morbidity and Immune Response After Cystectomy (INCyst Trial)
Status: RECRUITING
Conditions: Bladder Cancer|Interstitial Cystitis|Painful Bladder Syndrome|Neurogenic Bladder|Hemorrhagic Cystitis|Endometriosis|Bladder Disease
Interventions: DRUG: Immunonutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study To InvestigateThe Safety, Tolerability And Efficacy Of Nebulised Curosurf® In Preterm Neonates With Respiratory Distress Syndrome (RDS)
Status: TERMINATED
Conditions: Neonatal Respiratory Distress Syndrome
Interventions: DRUG: nCPAP (nasal Continuous Positive Airway Pressure) + Nebulised Curosurf® (Part I)|DRUG: nCPAP (nasal Continuous Positive Airway Pressure) + Nebulised Curosurf® (Part II)|OTHER: nCPAP (nasal Continuous Positive Airway Pressure) alone (Part I)|OTHER: nCPAP (nasal Continuous Positive Airway Pressure) alone (Part II)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction Immuno-chemotherapy and Concurrent Chemoradiotherapy With or Without Apatinib in Unresectable, Locally Advanced Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma|Efficacy|Toxicity
Interventions: DRUG: Induction Immunotherapy-Toripalimab|DRUG: Induction Chemotherapy-Albumin-paclitaxel combined with cisplatin|RADIATION: Radiotherapy|DRUG: Apatinib|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-exposure Option for Reducing HIV in the UK.(PROUD)
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Truvada (once daily tablet containing 300mg tenofovir disoproxil (TDF) and 200mg of emtricitabine (FTC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Japanese Study of the Combined Administration of Docetaxel With Prednisolone for Metastatic Hormone Refractory Prostate Cancer
Status: COMPLETED
Conditions: Therapy, Prostatic Neoplasms
Interventions: DRUG: docetaxel (XRP6976)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Based on Metabonomics Dryness Pathogen Type of OLP: a Dynamic Study
Status: UNKNOWN
Conditions: Oral Lichen Planus
Interventions: DRUG: Qingxuan Decoction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Assess the Drug-drug Interaction Potential Between Dapivirine Vaginal Ring-004, Containing 25 mg of Dapivirine, and Clotrimazole 10 mg/g (1%)
Status: COMPLETED
Conditions: HIV- Prevention
Interventions: DRUG: Dapivirine Ring-004|DRUG: Dapivirine Ring-004 for 28 days along with clotrimazole|DRUG: Clotrimazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Impact of Pre-procedural Intracoronary Nicorandil Injection to PREVENT reductioN Of decREased TIMI FLOW in Patients Who Undergoing Percutaneous Coronary Intervention for the Coronary Artery Disease
Status: RECRUITING
Conditions: No-Reflow Phenomenon|Coronary Artery Disease|Percutaneous Coronary Intervention
Interventions: DRUG: Nicorandil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Role of BP1.3656 on Alcohol Responses
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: BP1.3656|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Prospective Study of Different Digoxin Treatment Regimens in Egyptian Hospital
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: patients take 0.25 mg of digoxin daily except friday|DRUG: patients take 0.25 mg of digoxin daily except thursday and friday|DRUG: patients take 0.125 mg of digoxin daily|DRUG: digoxin dose is calculated using Jusko-Koup method and given daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pancreatic Islet Cell Transplantation - A Novel Approach to Improve Islet Quality and Engraftment
Status: COMPLETED
Conditions: Islet Cell Transplantation|Type 1 Diabetes
Interventions: DRUG: Islet cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-dose to Evaluate the Pharmacokinetics of GTX-101 and Subcutaneous Injectable Bupivacaine in Healthy Subjects
Status: UNKNOWN
Conditions: Postherpetic Neuralgia
Interventions: DRUG: GTX-101|DRUG: Bupivacaine HCl subcutaneous injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Unstable Angina Pectoris Trial
Status: COMPLETED
Conditions: Angina, Unstable|Cardiovascular Diseases|Coronary Disease|Heart Diseases|Myocardial Ischemia
Interventions: PROCEDURE: coronary artery bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Continuous Glucose Monitoring System Alerts on Diabetes Management in the Hospital
Status: RECRUITING
Conditions: Diabetes Mellitus
Interventions: DEVICE: CGM system with both glucose predictive alerts and threshold alerts on|DEVICE: CGM system with only glucose threshold alerts on|DEVICE: CGM system with glucose alerts off
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Neurally Adjusted Ventilatory Assist (NAVA) Prone vs Supine in Premature Infants
Status: RECRUITING
Conditions: Neonatal Oxygen Desaturation|Premature|Ventilator Lung; Newborn|Apnea of Prematurity
Interventions: OTHER: Body positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Fotemustin to Intensive Surveillance in Patients With High Risk Uveal Melanoma
Status: COMPLETED
Conditions: Uveal Melanoma
Interventions: DRUG: Adjuvant chemotherapy by Fotemustin|OTHER: Intensive surveillance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apatinib Plus Camrelizumab Combined With Docetaxel and S1 in First-line Treatment for Metastatic Gastric Cancer
Status: RECRUITING
Conditions: Metastatic Gastric Adenocarcinoma|Metastatic Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Camrelizumab|DRUG: Apatinib Mesylate|DRUG: S1|DRUG: Docetaxel injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding Visual Processing After Occipital Stroke
Status: NOT_YET_RECRUITING
Conditions: Vision Loss Partial|Vision; Loss, Both Eyes|Hemianopia, Homonymous|Hemianopia|Quadrantanopia|Stroke, Ischemic|Stroke - Occipital Infarction|Cortical Blindness|Occipital Lobe Infarct|Peripheral Visual Field Defect of Both Eyes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Open-label Brexpiprazole fMRI Trial in Adults With Major Depressive Disorder and Anxiety
Status: WITHDRAWN
Conditions: Major Depressive Disorder (MDD)
Interventions: DRUG: Brexpiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Greater Omentum Binding to the Pancreatic Stump to Prevent Pancreatic Fistula Following Distal Pancreatectomy
Status: UNKNOWN
Conditions: Pancreatic Fistula|Pancreatic Neoplasms
Interventions: PROCEDURE: greater omentum binding|PROCEDURE: Pancreatic stump exposed without omentum binding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Understanding Individual Differences in Working Memory Training and Transfer in Older Adults
Status: RECRUITING
Conditions: Cognitive Change
Interventions: BEHAVIORAL: N-back|BEHAVIORAL: Span|BEHAVIORAL: Multisensory
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Relative Bioavailability Study of Nirmatrelvir/Ritonavir Oral Powder Relative to the Commercial Tablets and Estimation of the Effect of Food on Bioavailability of the Nirmatrelvir/Ritonavir Oral Powder in Healthy Participants.
Status: COMPLETED
Conditions: Biological Availability
Interventions: DRUG: Nirmatrelvir/ ritonavir|DRUG: Nirmatrelvir/Ritonavir|DRUG: Nirmatrelvir/Ritonavir|DRUG: Nirmatrelvir/ritonavir|DRUG: Nirmatrelvir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of 18F-Fluorodeoxyglucose (FluGlucoScan) in Patients With Known or Suspected Soft Tissue Sarcoma
Status: TERMINATED
Conditions: Sarcoma
Interventions: PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ARomatherapy for Cognitive Trajectory in Chinese After Percutaneous Coronary Intervention (ARCTIC-PCI)
Status: UNKNOWN
Conditions: Percutaneous Coronary Intervention
Interventions: DRUG: Aromatherapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Does Post-operative Rinsing With a Monoject Syringe Result in as Much Post-operative Pain After Surgical Removal of Lower Impact Third Molars as no Post-operative Rinsing: a Randomized Controlled Equivalence Trial
Status: NOT_YET_RECRUITING
Conditions: Third Molar
Interventions: OTHER: Monoject syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I/II Eval Safety & Prelim Activity Nivolumab Comb W/Vorolanib Pts W/Refractory Thoracic Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Thymic Carcinoma|Non-small Cell Lung Cancer|Refractory Thoracic Tumors|Small-Cell Lung Cancer
Interventions: DRUG: Vorolanib|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Center Diagnostic, Cross-sectional Study of Coronary Microvascular Dysfunction
Status: RECRUITING
Conditions: Coronary Microvascular Disease|Ischemic Heart Disease|Myocardial Ischemia
Interventions: DRUG: Bivalirudin|DRUG: Adenosine|DRUG: Heparin|DEVICE: Pressure-Temperature Sensor Guidewire|DEVICE: Guiding Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Reusable Versus Disposable Draping System in Breast Reconstruction Surgery
Status: COMPLETED
Conditions: Mastectomy|Infections|Breast Reconstruction
Interventions: OTHER: Culture Swabs, Rodac Plate Cultures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Utility of Liposomal Bupivacaine Transversus Abdominal Plane Block for Open Myomectomy
Status: RECRUITING
Conditions: Fibroid Uterus
Interventions: DRUG: Bupivacaine|DRUG: Bupivacaine liposome|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "The Effect of Aerobic Exercise and Strength Training on Physical Activity Level, Quality of Life and Anxiety-Stress Disorder in Young Adults With and Without Covid-19"
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: BEHAVIORAL: Aerobic Exercise and Strength Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ulipristal Acetate In Disease Charcot-Marie-Tooth Type of 1A
Status: TERMINATED
Conditions: CMT1A
Interventions: DRUG: EllaOne|DRUG: EllaOne placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adrenocorticotropic Hormone (ACTH) Effects on Myelination in Subjects With MS
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: DRUG: Adrenocorticotropic hormone (ACTH) gel (H.P. Acthar®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemostasis in Open Acetabulum and Pelvic Ring Surgery Using Tranexamic Acid
Status: COMPLETED
Conditions: Acetabulum Fractures
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Regulation of Vitamin D Receptor (VDR),Calcium Sensing Receptor (CaSR), Cyclin D1,Ki67 and Proliferating Cell Nuclear Antigen (PCNA) in Primary Hyperparathyroidism
Status: UNKNOWN
Conditions: Primary Hyperparathyroidism (PHPT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: First-Line Capecitabine and Cetuximab for Metastatic Colorectal Ca in Elderly Patients
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: Capecitabine and Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of PDC-1421 Treatment in Adult Patients With Attention-Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention-Deficit Hyperactivity Disorder (ADHD)
Interventions: DRUG: PDC-1421 Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Pharmacodynamics of Mycophenolate Mofetil in Pediatric Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Triphasic CT, PET and MR Tumour With Pathological Findings in Colorectal Cancer Liver Metastases
Status: COMPLETED
Conditions: Liver Metastases|Colorectal Cancer
Interventions: PROCEDURE: CT, PET and MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Investigation of Dietary Supplement Liquid Shot Products on Mental Energy, Cognition (Acuity),and Mood
Status: COMPLETED
Conditions: Cognition|Mental Fatigue|Mood
Interventions: DIETARY_SUPPLEMENT: Placebo shot|DIETARY_SUPPLEMENT: Functional energy shot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: inflAmmatory maRkers in Blood and Thrombus Aspirated From Patients With acutE myocaRdial Infarction With St-segment elevAtion
Status: UNKNOWN
Conditions: Patients Admitted With the Diagnosis of ST-elevation Acute Coronary Syndrome
Interventions: OTHER: Biomarkers to analyze both intracoronary thrombi as blood
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Viable Human SARS-CoV-2 Specific T Cell Transfer in Patients at Risk for Severe COVID-19
Status: TERMINATED
Conditions: Moderate COVID-19-infection
Interventions: DRUG: human SARS-CoV 2 specific T lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Vasopressin Treatment in Children With Autism
Status: COMPLETED
Conditions: Autism|Autism Spectrum Disorder|ASD
Interventions: DRUG: Vasopressin (USP) Injectable Solution [Vasostrict]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Procalcitonin Antibiotic Consensus Trial (ProACT)
Status: COMPLETED
Conditions: Lower Respiratory Tract Infection (LRTI)
Interventions: OTHER: Procalcitonin level|OTHER: Results of procalcitonin (PCT) level to treating clinician|OTHER: Provide procalcitonin guideline to treating clinician|OTHER: Telephone Visit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Steroid Profile: Differentiating Testosterone Administration From (Simultaneous) Ethanol Consumption
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Testosterone gel|DRUG: Ethanol Solution|DRUG: Testosterone placebo (vaseline)|DRUG: Ethanol placebo (lemon-flavoured water)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Clinical Trial to Investigate the Pharmacokinetics and Safety of CKD-393
Status: UNKNOWN
Conditions: T2DM (Type 2 Diabetes Mellitus)
Interventions: DRUG: CKD-501, D759, D150|DRUG: CKD-393 0.5/100/1000 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cost-effectiveness of Genotype Guided Treatment With Antiplatelet Drugs in STEMI Patients: Optimization of Treatment (POPular Genetics)
Status: COMPLETED
Conditions: Myocardial Infarction|STEMI
Interventions: GENETIC: CYP2C19 genotyping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dispensing Study to Assess the Visual Performance of Optimised Prototype Contact Lenses
Status: COMPLETED
Conditions: Presbyopia|Refractive Error
Interventions: DEVICE: Etafilcon A|DEVICE: Etafilcon A|DEVICE: Nelfilcon A|DEVICE: Nesofilcon A|DEVICE: Nelfilcon A|DEVICE: Etafilcon A|DEVICE: Somofilcon A|DEVICE: 58% Poly-HEMA|DEVICE: Omafilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Protocol to Allow Treatment With ICL670 for Patients With or at Risk of Life-threatening Complications of Transfusional Iron Overload Who Are Unable to Tolerate Other Iron Chelators Because of Documented Severe Toxicity
Status: COMPLETED
Conditions: Transfusional Iron Overload
Interventions: DRUG: ICL670
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CDD Plus Bortezomib or CDDin Relapsed or Refractory Multiple Myeloma With Extramedullary Plasmacytoma
Status: UNKNOWN
Conditions: Extramedullary Plasmacytoma
Interventions: DRUG: CDD|DRUG: CDD Plus Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth Hormone in Neuroendocrine Dysfunction With Severe Fibromyalgia Syndrome
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Saizen®|DRUG: Placebo and Saizen®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Burch Colposuspension Versus Midurethral Sling for Treatment of Female Stress Urinary Incontinence a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Treatment of Female Stress Urinary Incontinence
Interventions: PROCEDURE: Laparoscopic Burch colposuspension and Mid-urethral slings (TVT and TOT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Basketball Pre-injury Attack Program to Reduce the Susceptibility of Injury in Youth Basketball Players
Status: COMPLETED
Conditions: Injury;Sports|Biomechanical Lesions|Musculoskeletal Injury|Sports Physical Therapy
Interventions: OTHER: Basketball Pre-injury Attack program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of Re-oxygenation After Inhalation of 50% Nitrous Oxide / 50% Oxygen Premix in Dental Cares
Status: TERMINATED
Conditions: Dental Cares Under Kalinox's Inhalation
Interventions: DRUG: Oxygène|DRUG: Air Médical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Drug-Drug Interaction Study of GK Activator (2) and Glyburide in Patients With Type 2 Diabetes.
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: GK Activator (2)|DRUG: Glyburide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Single-center, Randomized, Controlled Study of Sevelamer Carbonate in the Lipid Metabolism and Uric Acid Treatment of Obesity-Related Glomerulopathy
Status: TERMINATED
Conditions: Obesity and Glomerulopathy
Interventions: DRUG: High dosage Sevelamer Carbonate + Irbesartan|DRUG: Low dosage Sevelamer Carbonate + Irbesartan|DRUG: Irbesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Knee Osteoarthritis Treatment With Zilretta vs. Kenalog in the Context of Type II Diabetes
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee|Diabetes Mellitus, Type 2
Interventions: DRUG: triamcinolone acetonide extended-release injectable suspension; TCA-ER|DRUG: Triamcinolone Acetonide- Immediate Release;TCA-IR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Postop Steroids on Cardiovascular/Respiratory Function in Neonates Undergoing Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Heart Disease Congenital Complex
Interventions: DRUG: Hydrocortisone|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Single-agent Carlumab (an Anti-Chemokine Ligand 2 [CCL2]) in Participants With Metastatic Castrate-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Carlumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictability of Part-time Wearing of Removable Clear Aligner Therapy Versus Full Time
Status: COMPLETED
Conditions: Malocclusion, Angle Class I
Interventions: DEVICE: clear aligner treatment for orthodontics patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Placenta Delivery Method on Pain, Bleeding and Comfort
Status: NOT_YET_RECRUITING
Conditions: Placenta Abruptio
Interventions: DRUG: Uteratonic administration|OTHER: cord clamping|OTHER: delivery of the placenta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Natural History and Patient Journey in Dementia: a Nationwide Linked Electronic Health Records Study of 5.6 Million Individuals.
Status: UNKNOWN
Conditions: Dementia, Alzheimer, Electronic Health Records, Hospitalizations, Epidemiology, Comorbidity, United Kingdom, Incidence, Mortality, Cause of Death
Interventions: OTHER: The study does not have an intervention, but observe the dementia incidence of the UK disease-free population.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Minimal Enteral Nutrition on Mesenteric Blood Flow and Oxygenation in Neonates With HIE
Status: COMPLETED
Conditions: Hypoxic-Ischemic Encephalopathy
Interventions: DIETARY_SUPPLEMENT: Minimal enteral nutrition|DIETARY_SUPPLEMENT: Distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer mRNA Vaccine (mRNA-1644)
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV-1-infection
Interventions: BIOLOGICAL: eOD-GT8 60mer mRNA Vaccine (100µg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Duvelisib Ameliorates Manifestations of Pneumonia in Established Novel Coronavirus Infection (COVID-19)
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Duvelisib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Interaction Between JNJ-64417184 and JNJ-53718678 After Single and Multiple Dosing in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-53718678|DRUG: JNJ-64417184
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Dry Age-related Macular Degeneration
Status: TERMINATED
Conditions: Dry Age-related Macular Degeneration|Geographic Atrophy|Macular Degeneration|Retinal Disease|Retinal Degeneration
Interventions: DRUG: GEM103
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening for Sarcopenic Dysphagia and the Implementation of Measures to Prevent Its Complications in Geriatric Patients [DYSPHAGING-PILOT]
Status: RECRUITING
Conditions: Swallowing Disorder|Sarcopanic Dysphagia
Interventions: OTHER: EAT-10 (Eating assessment Tool) screening questionnaire|PROCEDURE: Protective measures for the upper airways
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: #Stayhealthy - Monitoring and Maintenance of Mental Health Under Conditions of Social Isolation During the Corona Crisis
Status: COMPLETED
Conditions: Mental Health Wellness 1
Interventions: BEHAVIORAL: Acceptance and commitment therapy (ACT) exercises|BEHAVIORAL: Positive psychology (PP) exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vortioxetine vs Sertraline in Mexicans
Status: COMPLETED
Conditions: Depression|Type 2 Diabetes Mellitus
Interventions: DRUG: Vortioxetine|DRUG: Sertraline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Induction Study of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 1)
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Mirikizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Beneficial Effects of Healthy Snacks on Appetite Control, Satiety, and Reward-driven Eating Behavior in Young People
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: High Protein|BEHAVIORAL: Low Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IRX-2 Regimen in Patients With Newly Diagnosed Stage II, III, or IVA Squamous Cell Carcinoma of the Oral Cavity
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Oral Cavity
Interventions: BIOLOGICAL: IRX-2|DRUG: Cyclophosphamide|DRUG: Indomethacin|DIETARY_SUPPLEMENT: Zinc-containing multivitamin|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validity, Reliability and Feasibility of an Automated Photographic Measurement/Assessment of Food Intake in the Hospitalized Elderly
Status: UNKNOWN
Conditions: Elderly People|Food Intake Measurement
Interventions: OTHER: Food weighing (gold standard)|OTHER: Automated photographic method (method to be evaluated)|OTHER: Semi-quantitative method (routine method)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nab-paclitaxel (Abraxane), Gemcitabine, and Capecitabine (Xeloda) for Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Neoplasms|Pancreatic Cancer|Adenocarcinoma
Interventions: DRUG: nab-paclitaxel, gemcitabine, capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corticosteroid Injection Versus Tendon Dry Needling for Subacromial Impingement Syndrome
Status: NOT_YET_RECRUITING
Conditions: Shoulder Pain|Shoulder Impingement Syndrome|Shoulder Impingement|Subacromial Impingement Syndrome|Subacromial Impingement
Interventions: PROCEDURE: Corticosteroid injection|PROCEDURE: Dry Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the COOP Group Approach for Children With Developmental Coordination Disorder (DCD)
Status: COMPLETED
Conditions: Developmental Coordination Disorder
Interventions: BEHAVIORAL: Cognitive Orientation to daily Occupational Performance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Auditory Processing in Spanish-English Bilinguals: Is Performance Better When Tested in Spanish or English?
Status: COMPLETED
Conditions: Auditory Processing Disorder
Interventions: DIAGNOSTIC_TEST: English APD assessment|DIAGNOSTIC_TEST: Spanish APD assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Opportunistic Salpingectomy on Ovarian Reserve in Patients Undergoing Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Benign Uterine Disease
Interventions: PROCEDURE: LH alone|PROCEDURE: LH with opportunistic salpingectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fascial Tissue Response To Manual Therapy: Implications In Long Covid Rehabilitation
Status: RECRUITING
Conditions: COVID-19
Interventions: OTHER: Guidebook|OTHER: Guidebook and Myofascial Reorganization® (RMF).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Endotoxin Absorption and Cytokine Removal Hemofilter on Severe Septic Shock
Status: COMPLETED
Conditions: Sepsis, Severe|Septic Shock
Interventions: DEVICE: oXiris blood purification set
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psilocybin-Assisted Therapy for the Treatment of Cancer-Related Anxiety in Patients With Metastatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic and Lymphatic System Neoplasm|Metastatic Malignant Solid Neoplasm
Interventions: OTHER: Counseling|DRUG: Psilocybin|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACURATE TA™ Valve Implantation: SAVI Registry (Surveillance Plan #2011-02) (TA-SAVI)
Status: COMPLETED
Conditions: Symptomatic Aortic Stenosis
Interventions: DEVICE: ACURATE TA™ Transapical Aortic Bioprosthesis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study in Sepsis Patients With Renal Failure
Status: TERMINATED
Conditions: Sepsis|Bacterial Infections and Mycoses
Interventions: DRUG: Placebo|DRUG: BIAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation of Timing of Pegfilgrastim Administration and PIBP.
Status: RECRUITING
Conditions: Pegfilgrastim|Bone Pain|Chemotherapy|Breast Cancer|Patient-reported Outcomes|Quality of Life
Interventions: OTHER: Timing of pegfilgrastim administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial Disease
Status: NOT_YET_RECRUITING
Conditions: Peripheral Arterial Disease|Painful Diabetic Neuropathy|Diabetes Mellitus, Type 2|Chronic Pain|Spinal Cord Stimulation|Chronic Pain Syndrome|Limb Pain
Interventions: DEVICE: Spinal cord stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Extension Trial to Evaluate the Long-term Safety of Apraglutide in Short Bowel Syndrome.
Status: ACTIVE_NOT_RECRUITING
Conditions: Short Bowel Syndrome
Interventions: DRUG: Apraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of Routine Intake of Fresh vs- Pasteurized Yoghurt on the Immune System in Healthy Adults
Status: COMPLETED
Conditions: Immune System|Innate Inflammatory Response
Interventions: OTHER: Pasteurised yoghurt|OTHER: Fresh yoghurt|OTHER: Sterilised yoghurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of JNJ-86974680 in Participants With Advanced Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Carcinoma, Non-small-Cell Lung
Interventions: DRUG: JNJ-86974680|DRUG: Cetrelimab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of the End-inspiratory Pause on Mechanical Ventilation.
Status: COMPLETED
Conditions: Anesthesia|Surgery
Interventions: PROCEDURE: End-inspiratory pause 10%|PROCEDURE: End-inspiratory pause 30%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Aesthetic Reconstruction of Onco-surgical Maxillary Defects Using FSF With and Without CAD/CAM Customized Cutting Guide
Status: UNKNOWN
Conditions: Maxillary Tumors
Interventions: PROCEDURE: FSF with CAD\CAM customized cutting guide|PROCEDURE: FSF without customized cutting guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial to Evaluate the Safety and Efficacy of Combination Therapy With Retrovir ( AZT ) and HIVID ( ddC ) Versus Retrovir, HIVID, and Wellferon ( Interferon Alfa-n1 ) for the Treatment of HIV Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Zalcitabine|DRUG: Interferon alfa-n1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study to Investigate Bladder Contractions in the Storage Phase and Related Bladder Sensations in Healthy Females and Females With Overactive Bladder (OAB) Using High Resolution and Conventional Urodynamics
Status: TERMINATED
Conditions: Healthy Subjects|Overactive Bladder
Interventions: PROCEDURE: High resolution urodynamic assessment|PROCEDURE: Conventional urodynamic assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Efficacy of Orally Administrated Probiotic Formula in Preventing a Recurrence of a Urinary Tract Infection During Pregnancy
Status: WITHDRAWN
Conditions: Urinary Tract Infections (UTIs)
Interventions: DIETARY_SUPPLEMENT: Urex Plus - containing L. rhamnosus GR-1 and L. reuteri RC-14|OTHER: Placebo - capsule with no active ingredient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Pentoxifylline and Vitamin E on Radiotherapy-induced Toxicity in Head & Neck Cancer Patients
Status: COMPLETED
Conditions: Head and Neck Neoplasms
Interventions: DRUG: Pentoxifylline|DRUG: Vitamin E|DRUG: Cisplatin|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of a Novel Class of Objective Myofascial Pain Assessments
Status: RECRUITING
Conditions: Myofascial Pain|Trigger Point Pain, Myofascial
Interventions: DIAGNOSTIC_TEST: Ultrasound|DIAGNOSTIC_TEST: Electrical impedance myography|DIAGNOSTIC_TEST: Excitability testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The PRONTO Study, a Global Phase 2b Study of NEOD001 in Previously Treated Subjects With Light Chain (AL) Amyloidosis
Status: COMPLETED
Conditions: AL Amyloidosis
Interventions: DRUG: NEOD001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of JNJ-42165279 on the Neural Basis of Anxiety Disorders in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-42165279 (100 mg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial to Assess the Influence of 4 Weeks' Treatment With Linagliptin as Compared to Glimepiride and Placebo on Endothelial Function in Patients With Type 2 Diabetes Using FMD (Flow-Mediated Vasodilation)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: Linagliptin|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Detection of Cerebral Ischemia With a Noninvasive Neurometabolic Optical Monitor
Status: COMPLETED
Conditions: Traumatic Brain Injury|Ischemic Stroke|Intracerebral Hemorrhage|Subarachnoid Hemorrhage|Acute Anoxic Encephalopathy
Interventions: DRUG: Indocyanine Green
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Resistance Training Associated With Whole-Body Vibration in Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Resistance training associated with vibration|OTHER: Resistance training associated with vibration sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase-I Trial of Pembrolizumab and Percutaneous Cryoablation Combination Followed by Nephron-Sparing Surgery or Cytoreductive Nephrectomy in Locally Advanced and Metastatic Renal Cell Carcinomas
Status: WITHDRAWN
Conditions: Renal Cell Carcinoma|Metastatic Kidney Cancer
Interventions: DRUG: Pembrolizumab Injection [Keytruda]|PROCEDURE: Cryoablation|PROCEDURE: Nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Fezolinetant to Treat Hot Flashes in Women Going Through Menopause
Status: COMPLETED
Conditions: Vasomotor Symptoms
Interventions: DRUG: fezolinetant|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Portable Monitoring for Diagnosis and Management of Sleep Apnea
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: OTHER: Portable (Embla Embletta X30 system and Respironic REMStar Auto M series with CFlex)|OTHER: Standard polysomnography (PSG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Hyperopic Population
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: Investigational senofilcon A C3 Multifocal Lens|DEVICE: delefilcon A Multifocal Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: iMRI Guided Resection in Cerebral Glioma Surgery
Status: COMPLETED
Conditions: Glioma
Interventions: PROCEDURE: iMRI|PROCEDURE: conventional neuronavigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phamacokinetics and Safety Profiles of DA-5210 10/1000mg in Healthy Subjects at Fed State
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DA-5210 10/1000mg|DRUG: DA-5210-R 10/1000mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arginine and Whole Brain Radiation Therapy for the Treatment of Patients With Brain Metastases
Status: NOT_YET_RECRUITING
Conditions: Metastatic Malignant Neoplasm in the Brain|Metastatic Malignant Solid Neoplasm
Interventions: DIETARY_SUPPLEMENT: Arginine|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Spectroscopy|RADIATION: Whole-Brain Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2/3 Multicenter, Controlled Trial Of rhBMP-2/CPM In Tibial Fractures
Status: TERMINATED
Conditions: Fractures
Interventions: DRUG: rhBMP-2/CPM|DRUG: rhBMP-2/CPM|DRUG: rhBMP-2/CPM|DRUG: rhBMP-2/CPM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Aureobasidium Pullulans Produced β-glucan on Musculoskeletal Biomarkers in Adults With Relative Sarcopenia
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Aureobasidium pullulans produced β-glucan group|DIETARY_SUPPLEMENT: placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Pharmacokinetics of NVP-1805 and Coadministration of NVP-1805-R1 With NVP-1805-R2
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: NVP-1805|DRUG: NVP-1805-R1and NVP-1805-R2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dopamine Versus Dobutamine for Treatment of Arterial Hypotension in Term and Preterm Neonates
Status: UNKNOWN
Conditions: Arterial Hypotension
Interventions: DRUG: Dobutamine|DRUG: Dopamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anesthetic Topical Adhesive (Synera™) to Reduce Injection Pain With Subcutaneous Multiple Sclerosis Medications
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Anesthetic Topical Adhesive Synera
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: P.F.C. Sigma Fixed Versus P.F.C. RP Mobile Bearing Total Knee Systems
Status: TERMINATED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: PFC Sigma Fixed Bearing|DEVICE: PFC Sigma Mobile Bearing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT