pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Addition of Etanercept and Extracorporeal Photopheresis (ECP) to Standard Graft-Versus-Host Disease (GVHD) Prophylaxis in Stem Cell Transplant
Status: COMPLETED
Conditions: Graft Versus Host Disease
Interventions: PROCEDURE: stem cell transplant|DRUG: tacrolimus (standard GVHD prophylaxis)|DRUG: mycophenolate (standard GVHD prophylaxis)|DRUG: etanercept|DRUG: methoxsalen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigation to Evaluate the Safety and Effectiveness of Cochlear Implantation in Children and Adults With Unilateral Hearing Loss/Single-sided Deafness
Status: RECRUITING
Conditions: Hearing Loss, Unilateral|Deafness, Unilateral
Interventions: DEVICE: The Cochlear™ Nucleus® Cochlear Implant (CI) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Creatine on Serum and Urine Creatinine
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DIETARY_SUPPLEMENT: Creatine Monohydrate|DIETARY_SUPPLEMENT: Creatine Ethyl Ester
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Camrelizumab Combined With Apatinib for Recurrent Resistant GTN
Status: COMPLETED
Conditions: Gestational Trophoblastic Disease
Interventions: DRUG: Apatinib|DRUG: Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Cranial Manual Therapy in the Treatment of Chronic Insomnia Disorder
Status: UNKNOWN
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: OTHER: Osteopathic Medicine|OTHER: Placebo therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Preoperative vs. Postoperative Rectal Misoprostol in Cesarean Section
Status: COMPLETED
Conditions: Neonatal Outcome
Interventions: DRUG: Misoprostol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Simmitinib Plus SG001 in Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: Simmitinib|DRUG: SG001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of SRT2104 on Endotoxin-induced Inflammation
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: Placebo|DRUG: SRT2104
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Sitagliptin Treatment in COVID-19 Positive Diabetic Patients
Status: UNKNOWN
Conditions: Covid19|Diabetes Mellitus, Type 2|CKD
Interventions: DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BEN-2001 in Parkinson Disease Patients With Excessive Daytime Sleepiness
Status: COMPLETED
Conditions: Excessive Daytime Sleepiness|Parkinson Disease
Interventions: DRUG: BEN-2001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Budesonide for Emergency Treatment of Acute Wheezing in Children
Status: COMPLETED
Conditions: Asthma|Acute Asthma
Interventions: DRUG: 0.5 mg/ml budesonide nebules|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Immune Response of IMVAMUNE (MVA-BN)Smallpox Vaccine in Patients With Atopic Disorders
Status: COMPLETED
Conditions: Dermatitis, Atopic|Hay Fever
Interventions: BIOLOGICAL: IMVAMUNE (MVA-BN)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating the Safety and Efficacy of Multiple Treatments in Participants With Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Cevostamab|DRUG: Lenalidomide|DRUG: Tocilizumab|DRUG: Iberdomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Effectiveness of a Parent and Child Mindfulness-Based Intervention for Child Venipuncture
Status: COMPLETED
Conditions: Pain|Needle Stick
Interventions: OTHER: Mindfulness-Based Condition|OTHER: Unfocused attention Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Evaluating the Clinical Performance and Usability of Novel Malaria RDTs in Brazil
Status: UNKNOWN
Conditions: Malaria
Interventions: DIAGNOSTIC_TEST: NxTek™ Malaria P.f plus Rapid Diagnostic Test (RDT) and NxTek™ Malaria P.f/P.v RDT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Romiplostim in Treatment of SAA in Adults Previously Untreated With or Refractory to Immunosuppressive Therapy
Status: WITHDRAWN
Conditions: Severe Aplastic Anemia (SAA)
Interventions: DRUG: Romiplostim|DRUG: Antithymocyte Globulin|DRUG: Cyclosporine A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhaled Treprostinil in Sarcoidosis Patients With Pulmonary Hypertension
Status: RECRUITING
Conditions: Sarcoidosis|Precapillary Pulmonary Hypertension|Interstitial Lung Disease
Interventions: DRUG: Inhaled Treprostinil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lornoxicam Versus Etoricoxib in Postoperative Pain After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Lornoxicam|DRUG: Etoricoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Genetic Polymorphism on Interactions of Clopidogrel and Cilostazol in Healthy Volunteers
Status: COMPLETED
Conditions: Interaction
Interventions: DRUG: Clopidogrel|DRUG: Cilostazol|DRUG: Clopidogrel/Cilostazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Vaccine Therapy in Treating Patients Who Are Undergoing Surgery for Stage IB, Stage II, or Stage IIIA Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: autologous tumor cell vaccine|DRUG: therapeutic autologous dendritic cells|PROCEDURE: adjuvant therapy|PROCEDURE: biological therapy|PROCEDURE: conventional surgery|PROCEDURE: surgery|PROCEDURE: tumor cell derivative vaccine|PROCEDURE: vaccine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Shock-wave Therapy in Patients With Myofascial Pain Syndrome
Status: COMPLETED
Conditions: Myofascial Pain Syndrome|Chronic Pain
Interventions: PROCEDURE: Radial Shock-Wave Therapy|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pelvic Physiotherapy in the Prevention of Vaginal Stenosis Secondary to the Radiotherapy
Status: UNKNOWN
Conditions: Gynecologic Cancer|Pathological Constriction
Interventions: BEHAVIORAL: Pelvic Physiotherapy|BEHAVIORAL: Standard care (SC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Magnetic Acupressure in Reducing Pain in Cancer Patients Undergoing Bone Marrow Aspiration and Biopsy
Status: COMPLETED
Conditions: Hematopoietic/Lymphoid Cancer|Pain
Interventions: OTHER: questionnaire administration|PROCEDURE: acupressure therapy|PROCEDURE: biopsy|PROCEDURE: bone marrow aspiration|PROCEDURE: pain therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Link Between the Sensitivity of Kisspeptin Signalling and Pubertal Onset in Boys.
Status: COMPLETED
Conditions: Reproductive Physiological Phenomena
Interventions: BIOLOGICAL: Kisspeptin-10 (metastin 45-54, Calbiochem, Darmstadt, Germany)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Conversion From Tacrolimus to Cyclosporine Microemulsion in Liver Transplant Patients With New Onset Diabetes After the 3rd Month Post-transplant
Status: COMPLETED
Conditions: Maintenance Liver Transplant Patients With New Onset Diabetes
Interventions: DRUG: Cyclosporine - cyclosporine microemulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vinegar Co-ingestion in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: placebo co-ingestion|DIETARY_SUPPLEMENT: vinegar co-ingestion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Combined Treatment With tDCS and Cognitive Training in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DEVICE: tDCS-Sham|DEVICE: tDCS-Active|OTHER: Cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Difficult Intubation in Intensive Care
Status: TERMINATED
Conditions: Difficult Intubation in ICU|Strictly More Than Two Laryngoscopies|Cormack Grade Three/Four
Interventions: DEVICE: Intubation with The McGrath Mac videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Rice Bran-based Supplemental Foods for the Treatment of Childhood Malnutrition
Status: COMPLETED
Conditions: Severe Acute Malnutrition
Interventions: DIETARY_SUPPLEMENT: Ready-to-use therapeutic food with heat stabilized rice bran|DIETARY_SUPPLEMENT: Ready-to-use therapeutic food (no rice bran)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Advanced or Metastatic Cholangiocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Cholangiocarcinoma
Interventions: DRUG: Carrilizumab|DRUG: Albumin-bound paclitaxel|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Adjunctive Zonisamide in Myoclonic Seizures Associated With Idiopathic Generalised Epilepsy
Status: TERMINATED
Conditions: Epilepsy
Interventions: DRUG: Zonisamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Combination Ixabepilone + Cisplatin
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Ixabepilone|DRUG: Cisplatin|DRUG: Ixabepilone|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Small Bowel Length Measurement Using Computed Tomography and Magnetic Resonance Imaging in Obese Patients
Status: RECRUITING
Conditions: Obesity|Bariatric Surgery Candidate
Interventions: DIAGNOSTIC_TEST: Measurement of the total small bowel length using CT scan and MRI with 3D reconstruction and AI tool
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Haploidentical Transplantation With CD3/CD19 Depleted Grafts in Patients With Hematologic Malignancies
Status: COMPLETED
Conditions: Hematologic Malignancies
Interventions: DRUG: Fludarabine|DRUG: Thiotepa|DRUG: Melphalan|DRUG: OKT-3|PROCEDURE: CD3/CD19 depletion on CliniMACS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dorsomedial Prefrontal Neuromodulation in Treatment-resistant Depression
Status: RECRUITING
Conditions: Treatment-resistant Depression|Major Depressive Disorder
Interventions: DEVICE: Prolonged intermittent theta burst stimulation (piTBS)|DEVICE: 20Hz rTMS|DEVICE: sham control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Donor-derived Cell-free DNA in Kidney Transplant Recipients
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Transplantation|Acute Rejection of Renal Transplant
Interventions: PROCEDURE: Biopsy|DIAGNOSTIC_TEST: Blood Biomarkers - cfDNA|DRUG: Antirejection therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Single Oral Dose Study of ASP015K in Healthy Volunteers Assessing the Relative Bioavailability Across Three Tablet Strengths From a New Formulation of ASP015K
Status: COMPLETED
Conditions: Bioavailability of ASP015K|Pharmacokinetics of ASP015K|Healthy Subjects
Interventions: DRUG: ASP015K
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: ImmunoPET Targeting Trophoblast Cell-Surface Antigen 2 (Trop-2) in Thyroid Cancer
Status: RECRUITING
Conditions: Tumor|Solid Tumor|Thyroid Cancer|Positron-Emission Tomography
Interventions: DIAGNOSTIC_TEST: standard-of-care imaging (18F-FDG and 68Ga-FAPI PET/CT), 68Ga-THP-Trop2 VHH PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Parecoxib on Post-craniotomy Pain
Status: COMPLETED
Conditions: Anaesthesia
Interventions: DRUG: Intravenous Parecoxib ('Dynastat' Pfizer)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CT-2103 in Treating Patients With Recurrent Ovarian Epithelial or Fallopian Tube Cancer or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: paclitaxel poliglumex
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: CD19/22 CAR T Cells (AUTO3) for the Treatment of Diffuse Large B Cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B Cell Lymphoma|Relapsed Diffuse Large B-Cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|DLBCL
Interventions: BIOLOGICAL: AUTO3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebrospinal Fluid Levels of Erlotinib in Patients Receiving Erlotinib For Stage III Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: OTHER: antitumor drug screening assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: A Novel Formulation of Bifidobacterium Longum BB536 and Lactobacillus Rhamnosus HN001 With Vitamin B6 on IBS Patients
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Zircombi|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Epcoritamab With Gemcitabine, Dexamethasone, and Cisplatin (GDP) Salvage Chemotherapy in Relapsed Refractory Large B-cell Lymphoma
Status: RECRUITING
Conditions: Large Cell Lymphoma, Diffuse|Relapsed Cancer|Refractory Cancer
Interventions: PROCEDURE: AutoSCT OR CAR T-cell Therapy|DRUG: GDP|DRUG: Epcoritamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron Absorption From a Micronutrient Powder Containing Galacto-oligosaccharides (GOS)
Status: COMPLETED
Conditions: Anemia, Iron-Deficiency
Interventions: DIETARY_SUPPLEMENT: Fortified maize porridge (MNP+iron)|DIETARY_SUPPLEMENT: Fortified maize porridge (MNP+iron+GOS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Botulinum Toxin A for the Treatment of Chronic Lumbar Back Pain
Status: UNKNOWN
Conditions: Chronic Low Back Pain
Interventions: DRUG: Botulinum Toxin A / Placebo|DRUG: Botulinum Toxin A / Botulinum Toxin A|DRUG: Placebo / Botulinum Toxin A|DRUG: Placebo / Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tamsulosin Phase III Clinical Trial -Double-Blind, Placebo Controlled Study in Male Patients With Lower Urinary Tract Syndrome
Status: COMPLETED
Conditions: Urinary Tract Diseases
Interventions: DRUG: Tamusulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Duct to Mucosa and Invagination Pancreaticojejunostomy After Pancreaticoduodenectomy:
Status: COMPLETED
Conditions: Pancreatic Anastomotic Leak
Interventions: PROCEDURE: Duct to mucosa PJ group|PROCEDURE: Invagination PJ group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Food Intake and Gut Hormones in Patients Who Have Undergone Upper Gastrointestinal Surgery for Cancer
Status: COMPLETED
Conditions: Esophageal Neoplasms|Stomach Neoplasms|Weight Loss|Malnutrition
Interventions: DRUG: Octreotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sore Throat in Primary Care - a Comparison of Phenoxymethylpenicillin and no Antibiotic Treatment
Status: UNKNOWN
Conditions: Sore Throat|Tonsillitis
Interventions: DRUG: Phenoxymethylpenicillin|OTHER: No antibiotic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Nilotinib in Steroid Dependent/Refractory Chronic Graft Versus Host Disease
Status: COMPLETED
Conditions: Bone Marrow Transplant Failure|Lymphoma, Non-Hodgkin|Lymphoma, T-Cell, Peripheral
Interventions: DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-energy Extracorporeal Shockwave Treatment for Patients After Radical Prostatectomy
Status: COMPLETED
Conditions: Erectile Dysfunction|Post-Op Complication|Prostatic Diseases
Interventions: PROCEDURE: Low intensity extracorporeal shock wave treatment (LI-ESWT)|PROCEDURE: Low intensity extracorporeal shock wave treatment (LI-ESWT) sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bupropion and Restless Legs Syndrome
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: Bupropion|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dipeptidyl Peptidase-4 Inhibitor (Sitagliptin) Therapy in the Inpatients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Hospitalization|Hyperglycemia
Interventions: DRUG: Sitagliptin|DRUG: glargine|DRUG: lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-up of the PEPITES Study to Evaluate Long-term Efficacy and Safety of Viaskin Peanut in Children
Status: UNKNOWN
Conditions: Peanut Allergy
Interventions: DRUG: Viaskin Peanut 250µg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of PQ Grass in Subjects With Seasonal Allergic Rhinitis and/or Rhinoconjunctivitis Induced by Grass Pollen
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis|Rhinoconjunctivitis
Interventions: BIOLOGICAL: PQ Grass|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Protein Supplement on Paraspinal Muscles in Spine Surgery
Status: COMPLETED
Conditions: Spine Surgery
Interventions: DRUG: Three sachet of protein supplement to be mixed in with water used daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Glycerol-Phenylbutyrate Treatment in Children With MCT Mutation (Allan-Herndon- Dudley Syndrome)
Status: UNKNOWN
Conditions: Monocarboxylate Transporter 8 Deficiency
Interventions: DRUG: Glycerol Phenylbutyrate 1100 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Efficacy and Safety of Recombinant Factor VIII （rFVIII）Treatment of Severe or Moderately Severe Hemophilia A
Status: UNKNOWN
Conditions: Hemophilia A
Interventions: DRUG: Recombinant Factor VIII (50 IU/kg)|DRUG: Recombinant Factor VIII (On-demand treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adebrelimab Plus Chemo and Recaticimab Perioperative Treatment for Resectable NSCLC
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Adebrelimab plus albumin-bound paclitaxel, carboplatin and recaticimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Leuprolide 11.25 mg and 30 mg Administered Every 3 Months to Treat Central Precocious Puberty
Status: COMPLETED
Conditions: Puberty, Precocious
Interventions: DRUG: Leuprolide acetate 11.25 mg|DRUG: Leuprolide acetate 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Orally Ingesting Branched Chained Amino Acids on Delayed Onset Muscle Soreness in Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes|Healthy Individuals
Interventions: DIETARY_SUPPLEMENT: Branched Chained Amino Acids|OTHER: Cellulose Placebo mix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Physiological Flow of Liquids in Healthy Swallowing
Status: COMPLETED
Conditions: Deglutition|Healthy Swallowing|Aging
Interventions: OTHER: Starch-thickened liquids|OTHER: Xanthan-gum thickened liquids|COMBINATION_PRODUCT: Barium concentration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety Study of Abatacept to Treat Lupus Nephritis
Status: TERMINATED
Conditions: Lupus Nephritis
Interventions: BIOLOGICAL: BMS-188667|DRUG: Mycophenolate mofetil|DRUG: Prednisone|BIOLOGICAL: Placebo matching with BMS-188667
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab, Chemotherapy, and Radiation Therapy With or Without Surgery in Treating Patients With Anaplastic Thyroid Cancer
Status: COMPLETED
Conditions: Thyroid Gland Undifferentiated (Anaplastic) Carcinoma
Interventions: DRUG: Docetaxel|DRUG: Doxorubicin Hydrochloride|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Blood Pressure Reduction and Weight Loss Program in a Low Income, Ethnically Diverse Population (The Be Fit, Be Well [BFBW] Study)
Status: COMPLETED
Conditions: Obesity|Hypertension
Interventions: BEHAVIORAL: Lifestyle Modification Program|BEHAVIORAL: Usual Care and Reading Materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ramucirumab (LY3009806) in Combination With Capecitabine and Cisplatin in Participants With Stomach Cancer
Status: COMPLETED
Conditions: Metastatic Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Ramucirumab|DRUG: Capecitabine|DRUG: Cisplatin|DRUG: Placebo|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Toll-like Receptor (TLR) 7 Agonist, Cyclophosphamide, and Radiotherapy for Breast Cancer With Skin Metastases
Status: COMPLETED
Conditions: Breast Cancer|Metastatic Breast Cancer|Recurrent Breast Cancer
Interventions: RADIATION: Radiation|DRUG: Imiquimod|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-day Versus Early Drain Removal Following PD: a Randomized Controlled Trial
Status: RECRUITING
Conditions: Pancreas Fistula Abdominal Drains
Interventions: BEHAVIORAL: 1st day removal of abdominal drain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intravenous Iron for Correction of Anaemia After Colorectal Surgery
Status: UNKNOWN
Conditions: Anemia, Iron-Deficiency|Intravenous Drug Usage|Colorectal Neoplasms|Colorectal Surgery
Interventions: DRUG: Iron isomaltoside|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mismatched Transplantation Using High-dose Post-transplant Cyclophosphamide
Status: COMPLETED
Conditions: Blood Stem Cell Transplant Failure|Leukemia|Hematologic Malignancies
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Melphalan|DRUG: Mesna|DRUG: Rituximab|PROCEDURE: Stem Cell Transplantation|DRUG: Thiotepa|DRUG: Tacrolimus|DRUG: Mycofenolate mofetil|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Atezolizumab With or Without Tiragolumab in Participants With Unresectable Esophageal Squamous Cell Carcinoma Whose Cancers Have Not Progressed Following Definitive Concurrent Chemoradiotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Tiragolumab|DRUG: Atezolizumab|DRUG: Tiragolumab Matching Placebo|DRUG: Atezolizumab Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Metformin on In Vitro Fertilization Outcomes in Overweight and Obese PCOS Women
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Metformin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Oral Desensitization to Peanut in Peanut-Allergic Children and Adults Using Characterized Peanut Allergen OIT
Status: COMPLETED
Conditions: Peanut Allergy
Interventions: BIOLOGICAL: AR101 powder provided in capsules|BIOLOGICAL: Placebo powder provided in capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post Market Usability Evaluation Of The PicoSure Pro Device
Status: COMPLETED
Conditions: Wrinkle|Acne Scars|Benign Epidermal Pigmented Lesions|Benign Dermal Pigmented Lesions|Tattoo Removal
Interventions: DEVICE: PicoSure Pro Device|DEVICE: PicoSure Device|DRUG: Topical Cosmeceuticals
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Preparatory Information on Anxiety and Treatment Adherence in Heart Surgery Patients
Status: RECRUITING
Conditions: Heart Surgery
Interventions: BEHAVIORAL: Preparatory information for ICU stay|BEHAVIORAL: Usual information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ajmaline Utilization in the Diagnosis and Treatment of Cardiac Arrhythmias
Status: COMPLETED
Conditions: Atrial Fibrillation|Tachycardia, Ventricular|Brugada Syndrome
Interventions: DRUG: flecainide|DRUG: ajmaline|DRUG: procainamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Soaking Complementary Foods Flour on Hemoglobin Concentration, Anthropometric Deficits and Episode of Diarrheal, Cough and Fever Morbidities
Status: COMPLETED
Conditions: Anemia
Interventions: OTHER: counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Role of Fractional Vascular Laser Therapy in the Management of Burn Scars
Status: RECRUITING
Conditions: Burn Scar
Interventions: DEVICE: Fractional Vascular Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy and Safety of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Regimen Versus Boosted Protease Inhibitor (bPI) Along With Emtricitabine/Tenofovir Disoproxil Fumarate (FTC/TDF) Regimen in Virologically-Suppressed, HIV-1 Infected Participants
Status: COMPLETED
Conditions: Human Immunodeficiency Virus Type 1
Interventions: DRUG: D/C/F/TAF|DRUG: Boosted Protease Inhibitor (bPI)|DRUG: FTC/TDF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diurnal Variation in Hypertensive Stroke Patients
Status: COMPLETED
Conditions: Hypertension|Stroke
Interventions: DRUG: Amlodipine, Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wheelchair-bound Senior Elastic Band (WSEB) Exercise Program for the Demented Seniors
Status: COMPLETED
Conditions: Dementia
Interventions: OTHER: Wheelchair-bound Senior Elastic Band exercise program (WSEB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Learn How Different Forms of the Study Medicine Called PF-06954522 Are Taken up Into the Blood in Healthy Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Participants
Interventions: DRUG: PF-06954522 IR (Formulation 1)|DRUG: PF-06954522 MR (Formulation 2)|DRUG: PF-06954522 MR (Formulation 3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of 16-week Dietary Intake of Food Supplements Containing Collagen on Dermis Density and Other Skin Parameters
Status: COMPLETED
Conditions: Dermis Density|Wrinkles|Skin Hydration|Dermis Thickness|Skin Texture|Skin Elasticity
Interventions: DIETARY_SUPPLEMENT: CP5HA|DIETARY_SUPPLEMENT: Placebo syrup|DIETARY_SUPPLEMENT: CP5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinicial Trial to Evaluate the Efficacy and Safety of DWJ211 in Patient With Moderate or Severe Submental Fat
Status: COMPLETED
Conditions: Treatment for Submental Fat
Interventions: DRUG: DWJ211|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact Evaluation of WFP's Fresh Food Voucher Pilot Programme in Ethiopia
Status: COMPLETED
Conditions: Diet; Deficiency|Malnutrition
Interventions: BEHAVIORAL: BCC-Only|OTHER: Small-voucher|OTHER: Large-voucher
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Computerized Intervention Targeting the Error-Related Negativity and Balance N1 in Anxious Children
Status: RECRUITING
Conditions: Anxiety Disorders|Generalized Anxiety Disorder|Social Anxiety Disorder|Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Psycho-social, computerized intervention targeting error sensitivity|BEHAVIORAL: Psycho-social, computerized intervention on healthy lifestyle choices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: NeuRx Diaphram Pacing System (DPS) Use in Amyotrophic Lateral Sclerosis (ALS)
Status: WITHDRAWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DEVICE: NeuRx DPS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurocircuitry of Obsessive-Compulsive Disorder: Modulation by Transcranial Magnetic Stimulation
Status: ACTIVE_NOT_RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Transcranial Magentic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparison of the Effect of Suture Material on Blepharoplasty Incision
Status: COMPLETED
Conditions: Dermatochalasis|Ptosis, Eyelid
Interventions: PROCEDURE: Randomized laterality of suture materials for closure (6-0 polypropylene monofilament suture vs fast absorbing gut suture on right eyelid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Safety and Efficacy Comparison of NEVANAC 0.1% to Vehicle After Cataract Surgery in Diabetic Retinopathy Patients
Status: COMPLETED
Conditions: Macular Edema
Interventions: DRUG: Nepafenac ophthalmic suspension, 0.1% (NEVANAC)|OTHER: Nepafenac ophthalmic suspension vehicle|DRUG: Prednisolone acetate ophthalmic suspension (OMNIPRED)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dose Comparison of Misoprostol for Cervix Ripening Before Operative Hysteroscopy.
Status: COMPLETED
Conditions: Cervix; Open
Interventions: DRUG: Misoprostol 200mcg Tab|DRUG: Misoprostol 800mcg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ropivacaine Through Continuous Infusion Versus Epidural Morphine for Postoperative Analgesia After Emergency Cesarean Section
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Ropivacaine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bone Ultrasound to Access Fracture Healing
Status: COMPLETED
Conditions: Forearm Fracture|Clavicle Fracture
Interventions: PROCEDURE: Ultrasound on fractured bone|PROCEDURE: Ultrasound on contralateral intact bone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of NeuroAD on Alzheimer Patients
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DEVICE: NeuroAD|DEVICE: Sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Comparison of 2 Daily Disposable Contact Lenses - Pilot Study 2
Status: COMPLETED
Conditions: Refractive Errors|Myopia
Interventions: DEVICE: Verofilcon A contact lenses|DEVICE: Somofilcon A contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Assess the Safety, Tolerability, and Activity of Oral SRT2104 Capsules Administered for 28 Days to Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: SRT2104
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Modulation Of Frontal EEG Alpha Oscillations During Maintenance and Emergence Phases of General Anesthesia
Status: UNKNOWN
Conditions: Postoperative Delirium
Interventions: PROCEDURE: Alpha Optimization|BEHAVIORAL: Emergence from anesthesia with propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunotherapy Combined With Radiation and Influenza Vaccine for Pancreatic Cancer.
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|BIOLOGICAL: Influenza vaccine|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACT™ Balloons Versus Artificial Urinary Sphincter (AMS800™) for the Treatment of Female Stress Urinary Incontinence
Status: UNKNOWN
Conditions: Urinary Incontinence
Interventions: DEVICE: ACT™ device|DEVICE: AMS 800 ™ device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Copanlisib With Dose-Adjusted EPOCH-R in Relapsed and Refractory Burkitt Lymphoma and Other High-Grade B-cell Lymphomas
Status: TERMINATED
Conditions: Burkitt Lymphoma|High-grade B-cell Lymphoma|T-cell/Histocyte-rich Large B-cell Lymphoma|Diffuse Large B-Cell Lymphoma (DLBCL)|Germinal Center B-cell Type (GCB)
Interventions: BIOLOGICAL: Rituximab|DRUG: Etoposide|BIOLOGICAL: Copanlisib|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|DIAGNOSTIC_TEST: ECHO|DIAGNOSTIC_TEST: EKG|DIAGNOSTIC_TEST: MRI Brain|DIAGNOSTIC_TEST: 18F-FDG - PET|DIAGNOSTIC_TEST: CT Scan|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|DIAGNOSTIC_TEST: Lumbar Puncture (LP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rebeccamycin Analogue in Treating Women With Stage IIIB or Stage IV Breast Cancer
Status: COMPLETED
Conditions: Male Breast Cancer|Recurrent Breast Cancer|Stage IIIB Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: becatecarin|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of SCH 900776 (MK-8776) With and Without Cytarabine in Participants With Acute Leukemias (P05247)
Status: TERMINATED
Conditions: Myelogenous Leukemia, Acute|Leukemia, Lymphocytic, Acute|Leukemia, Lymphoblastic, Acute, Philadelphia-Positive|Myelogenous Leukemia, Chronic, Aggressive Phase
Interventions: DRUG: MK-8776|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Peri- Operative Intra Venous Teranexamic Acid Reduces Blood Loss After Total Knee Arthroplasty: A Double Blind Randomized Placebo Controlled Clinical Trial
Status: COMPLETED
Conditions: Knee Arthroplasty, Total
Interventions: DRUG: Tranexamic Acid|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of ASTX030 (Cedazuridine in Combination With Azacitidine) in MDS, CMML, or AML
Status: RECRUITING
Conditions: Myelodysplastic Syndromes|Chronic Myelocytic Leukemia|Acute Myeloid Leukemia|Myelodysplastic Syndrome/Neoplasm
Interventions: DRUG: Azacitidine|DRUG: ASTX030 (cedazuridine + azacitidine)|DRUG: Cedazuridine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Immune Response to Two Pneumococcal Vaccines in HIV-Infected Pregnant Women
Status: WITHDRAWN
Conditions: Pneumococcal Infections|HIV Infections
Interventions: BIOLOGICAL: PPV-23 Vaccine|BIOLOGICAL: PCV-13 Vaccine|BIOLOGICAL: Placebo Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of 0.0003% Calcitriol, 0.1% Tacrolimus, and Petrolatum for the Treatment of Pityriasis Alba
Status: COMPLETED
Conditions: Pityriasis Alba
Interventions: DRUG: Tacrolimus|DRUG: Calcitriol|DRUG: Petrolatum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Platelet Rich Plasma (PRP) for Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: PRP|BIOLOGICAL: Plasma|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RISAS Procedure in Node Positive Breast Cancer Following NAC
Status: COMPLETED
Conditions: Breast Neoplasm|Neoadjuvant Therapy|Axillary Lymph Nodes|Pathological Complete Response
Interventions: PROCEDURE: RISAS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Prospective Multicentre Study Evaluating the Outcomes of the Abdominal Wall Dehiscence Repair Using Posterior Component Separation With Transversus Abdominis Muscle Release Reinforced by a Retro-muscular Mesh - Filling a Step
Status: COMPLETED
Conditions: Abdominal Wall Defect
Interventions: PROCEDURE: outcomes of complete burst abdomen repair using posterior component separation technique with transversus abdominis muscle release reinforced by sublay mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Dose Escalation Study of PCSK9 Inhibitor (JS002) in Health Subjects
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: JS002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study to Learn How the Study Drug Elinzanetant (BAY 3427080) Affects the Way the Drug Dabigatran Moves Into, Through and Out of the Body in Healthy Male and Female Participants
Status: COMPLETED
Conditions: Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men|Hot Flashes|Healthy Volunteers
Interventions: DRUG: Elinzanetant (BAY3427080)|DRUG: Dabigatran etexilate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Modafinil Effects on EEG Biomarkers of Reward and Motivation
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DRUG: Modafinil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Neoadjuvant Chemoradiation in Patients With Borderline Resectable Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Neoadjuvant chemoradiation|PROCEDURE: Upfront surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adding Intra-articular Dexmedetomidine to Levobupivacaine for Postoperative Analgesia in Arthroscopic Knee Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Levobupivacaine|DRUG: Dexmedetomidine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Esthetic Crown Lengthening With Closed Piezoelectric in Comparison to Open Flap Approach
Status: RECRUITING
Conditions: Altered Passive Eruption of Teeth
Interventions: PROCEDURE: ECL- mPZ|PROCEDURE: ECL-OF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT