pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Assess Safety, Immunogenicity and Parasite Growth Inhibition of an Asexual Blood Stage Vaccine for P. Falciparum Malaria
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: AMA1-C1/Alhydrogel® + CPG 7909
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Challenges Faced By Neurophysiotherapist While Consultation Through Tele-rehabilitation
Status: COMPLETED
Conditions: Stroke, Parkinson' s Disease, Neurological Impairments, Tele-rehabilitation
Interventions: OTHER: Opinions about tele-rehabilitation for consulting a clients with neurological impairments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Ketorolac at Three Doses in Children With Acute Pain
Status: RECRUITING
Conditions: Acute Pain|Abdominal Pain|Migraine|Appendicitis Acute|Renal Colic|Biliary Colic
Interventions: DRUG: Ketorolac Tromethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Simvastatin and Gemcitabine in Pancreatic Cancer Patients
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine+simvastatin|DRUG: Gemcitabine+Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation in Intensive Care Unit Patients
Status: COMPLETED
Conditions: Dietary Supplements|Intensive Care Unit|Vitamin D Deficiency|Vitamin D Toxicity
Interventions: DIETARY_SUPPLEMENT: Vitamin D supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MesoHep II: Intraperitoneal Low Molecular Weight Heparin in Peritoneal Dialysis
Status: TERMINATED
Conditions: Inflammation|Nutrition|Peritoneal Dialysis
Interventions: DRUG: tinzaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose:
Clinical trial: CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies
Status: RECRUITING
Conditions: Hematologic Malignancy|ALL, Childhood|AML, Childhood|Lymphoma|MDS
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: CD70-CAR T cell infusion (Autologous)|DRUG: Mesna
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Registry to Evaluate the Effective Incidence of Chronic Thromboembolic Pulmonary Hypertension in Germany
Status: UNKNOWN
Conditions: CTEPH|Chronic Thromboembolic Pulmonary Hypertension
Interventions: OTHER: Registration of the diagnosis "CTEPH"
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ABC Blocks for Cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: Pain
Interventions: DRUG: ABC block with bupivacaine/liposomal bupivacaine|DRUG: ABC block with saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Emotional, Physical and Cognitive Benefits of Purposeful Green Space Activities on Seniors
Status: COMPLETED
Conditions: Loneliness|Social Isolation|Mood|Well Aging|Physical Activity|Mobility Limitation
Interventions: OTHER: Green space
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Outcome of Specific IgE Level in Children With IgE-mediated Wheat Allergy After Stop Using Wheat Containing Skin Care
Status: TERMINATED
Conditions: Wheat Allergy|Children
Interventions: OTHER: wheat containing skin care products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Gap Junction Potentiation of Endothelial Function With Rotigaptide
Status: COMPLETED
Conditions: Vascular Disease|Heart Disease
Interventions: DRUG: Rotigaptide|OTHER: Forearm vascular study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing Fresh Random Platelets and Autologous Cryopreserved Thrombosol Treated Autologous Platelets
Status: TERMINATED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: Platelet Transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dosing of Tenofovir and Efavirenz in Antiretroviral Therapy
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Tenofovir|DRUG: Lamivudine|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block Versus Serratus Anterior Block on Post Mastectomy Pain Syndrome
Status: UNKNOWN
Conditions: Breast Cancer|Post-mastectomy Pain Syndrome|Acute Pain
Interventions: PROCEDURE: Serratus Anterior Plane Block|PROCEDURE: Erector Spinae Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Primary Prophylaxis for Variceal Bleed in Biliary Atresia
Status: UNKNOWN
Conditions: Portal Hypertension, Biliary Atresia
Interventions: DRUG: Propanolol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of NT 201 in the Treatment of Enlarged Pores and Excessive Sebum Production in the Face
Status: COMPLETED
Conditions: Enlarged Pores|Sebum Production
Interventions: DRUG: NT 201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of 6 Weeks Jump Training on Sand Versus Hard Surfaces on Jump Landing and Performance in Young Females
Status: RECRUITING
Conditions: Frontal Plane Projection Angle|Maximal Countermovement Jump|Repeated 10/5
Interventions: OTHER: sand jump training|OTHER: land jump training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Usability of the Honda Walking Assist Device (HWA) in the Home Environment
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke
Interventions: DEVICE: Honda Walk Assist (HWA) device|OTHER: SRALab fitness center membership
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Patient Satisfaction of Miralax and Gatorade Versus Movi Prep
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: comparing 2 drugs on their effect on the bowel preparation for colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: The Impact of Experienced Endoscopy Nurse Participation on Polyp and Adenoma Detection During Colonoscopy
Status: COMPLETED
Conditions: Polyp|Adenoma
Interventions: PROCEDURE: Colonoscopist only|PROCEDURE: Experienced Endoscopy Nurse Participation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systematic Radioiodine Administration Versus Decision of Radioiodine Treatment Guided by a Post-operative Work-up
Status: RECRUITING
Conditions: Thyroid Cancer|Intermediate Risk
Interventions: DRUG: Systematic RAI-treatment|OTHER: Decision of RAI-treatment guided by a post-operative assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Versus Late Stopping of Antibiotics in Children With Cancer and High-risk Febrile Neutropenia
Status: RECRUITING
Conditions: Febrile Neutropenia
Interventions: DRUG: Piperacillin and Tazobactam for Injection|DRUG: Cefepime Injection|DRUG: Ceftazidime Injection|DRUG: Vancomycin Injection|DRUG: Amikacin Injection|DRUG: Ciprofloxacin|DRUG: Piperacillin and Tazobactam for Injection|DRUG: Cefepime Injection|DRUG: Ceftazidime Injection|DRUG: Vancomycin Injection|DRUG: Amikacin Injection|DRUG: Ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protection of Cardiac Function With Left Bundle Branch Pacing in Patients With Atrioventricular Block
Status: RECRUITING
Conditions: Atrioventricular Block
Interventions: PROCEDURE: Left bundle branch pacing|PROCEDURE: Right ventricular pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Warm Saline Distension Media on Relieving Pain in Office Hysteroscopy
Status: UNKNOWN
Conditions: Hysteroscopy
Interventions: OTHER: Warm saline distension media in office hysteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Phase I Study of OPC-61815
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DRUG: OPC-61815 16mg|DRUG: OPC-61815 32mg|DRUG: Moxifloxacin|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-pulsed 1064 nm Nd-YAG Laser Versus TCA 20% in Treatment of Keratosis Pilaris
Status: COMPLETED
Conditions: Keratosis Pilaris
Interventions: DEVICE: Nd-YAG laser|DRUG: TCA 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Drug Levels, Physical and Chemical Changes, and Removal of BMS-986196 in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: [14C]-BMS-986196
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Allergenicity of AMPHADASE INJECTION (Hyaluronidase Injection USP)
Status: COMPLETED
Conditions: Allergic Skin Reaction
Interventions: DRUG: Hyaluronidase|DRUG: Histamine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Comparison of Outcomes of Multiple Platforms for Assisted Robotic - Prostate
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DEVICE: DaVinci RARP|DEVICE: Hugo RARP|DEVICE: Versius RARP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: LOQTEQ® Antibacterial Pre-Market Study
Status: RECRUITING
Conditions: Fractures, Open|Fractures, Closed|Surgical Site Infection|Fracture of Fibula
Interventions: DEVICE: Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness of Voriconazole + Micafungin Versus Voriconazole Alone for Invasive Aspergillosis
Status: WITHDRAWN
Conditions: Aspergillosis/Blood|Aspergillosis/Invasive
Interventions: DRUG: micafungin|DRUG: voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy When Transitioning From a Current Disease Modifying Therapy (DMT) to Ublituximab
Status: RECRUITING
Conditions: Relapsing Multiple Sclerosis
Interventions: BIOLOGICAL: Ublituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of CBT-I in Cancer Clinics
Status: UNKNOWN
Conditions: Insomnia
Interventions: BEHAVIORAL: Web-based cognitive-behavioral therapy for insomnia (CBT-I)|BEHAVIORAL: Professionally-administered booster face-to-face CBT-I sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluoroscopy Versus Ultrasound Guidance for Sacral Lateral Branch Radiofrequency Ablation
Status: COMPLETED
Conditions: Sacroiliac Joint Arthritis|Back Pain
Interventions: PROCEDURE: Sacral lateral branch radiofrequency ablation under ultrasound guidance|PROCEDURE: Sacral lateral branch radiofrequency ablation under fluoroscopy guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Acupuncture and Intracutaneous Needles in Pediatric Cancer Patients: a Retrospective Study (ACUSAFE2021)
Status: COMPLETED
Conditions: Cancer Pediatric|Neutropenia|Thrombocytopenia|Bacteremia|Infection;Skin;Localised|Safety Issues
Interventions: PROCEDURE: acupuncture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of DNA Testing and Gene Expression Profiling to Help Transition Kidney Transplant Recipients to Belatacept-only Immunosuppression
Status: ENROLLING_BY_INVITATION
Conditions: Kidney Transplant Immunosuppression
Interventions: DIAGNOSTIC_TEST: Allosure and TruGraf|OTHER: Immunosuppression Taper
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zanubrutinib and Lenalidomide as Maintenance Therapy in DLBCL
Status: NOT_YET_RECRUITING
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Zanubrutinib plus Lenalidomide as Maintenance Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Oral Difelikefalin for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica
Status: TERMINATED
Conditions: Pruritus|Notalgia Paresthetica
Interventions: DRUG: difelikefalin 2.0 mg tablets|DRUG: difelikefalin 1.0 mg tablets|DRUG: difelikefalin 0.25 mg tablets|DRUG: Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Histology of Implantation Biopsies and Kidney Allograft Outcomes
Status: COMPLETED
Conditions: Kidney Graft Dysfunction
Interventions: PROCEDURE: Intraoperative kidney allograft preimplantation biopsy; Intraoperative kidney allograft postreperfusion biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot Project of Virologic, Pharmacologic and Immunologic Correlates of Gastrointestinal-Associated Lymphoid Tissue Immune Reconstitution Following Maraviroc Therapy
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: maraviroc in combination with 2 NRTIs (dual nucleoside reverse transcriptase inhibitor)|DRUG: maraviroc plus raltegravir in combination with 2 NRTIs (dual nucleoside reverse transcriptase inhibitor)|DRUG: efavirenz [or other NNRTI (non-nucleoside reverse transcriptase inhibitor)]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Based Stress Reduction to Improve Neuropsychological Functioning in Acquired Brain Injury
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Mindfulness-based Stress Reduction|BEHAVIORAL: Brain Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial Evaluating Safety and Immunogenicity of MVA85A-IMX313 Compared to MVA85A in BCG Vaccinated Adults
Status: COMPLETED
Conditions: Tuberculosis (TB)
Interventions: BIOLOGICAL: MVA85A-IMX313|BIOLOGICAL: MVA85A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The RENEW Trial: A Multi-Center, Randomized, Double-Masked, Parallel-Group, Vehicle-Controlled, Adaptive Phase 3 Clinical Trial to Assess the Safety and Efficacy of Subjects With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Reproxalap Ophthalmic Solution (0.25%) QID|DRUG: Vehicle Ophthalmic Solution QID|DRUG: Reproxalap Ophthalmic Solution (0.25%) QID to BID|DRUG: Vehicle Ophthalmic Solution QID to BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Gamma Camera Used Intraoperatively for ID of Sentinel Lymph Nodes w/ Lymphoscintigraphy
Status: COMPLETED
Conditions: Multiple Myeloma|Breast Cancer
Interventions: DEVICE: Prototype intraoperative handheld gamma camera (pIHGC)|DEVICE: Lymphoscintigraphy with intraoperative gamma probes (GP)|RADIATION: radioactive Tc99M
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Antibiotic Prophylaxis in Bariatric Surgery With Cefazolin: Concentration in Adipose Tissue
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Cefazolin used in antimicrobial prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Tai Chi Practice on Blood Pressure and Brain Health Among Older Adults With Hypertension (ACTION)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension|Cognitive Decline
Interventions: BEHAVIORAL: Tai Chi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cytochrome P450 Inhibition to Decrease Dosage of Dasatinib for Chronic Myelogenous Leukemia
Status: RECRUITING
Conditions: Chronic Myeloid Leukemia, Chronic Phase
Interventions: DRUG: Dasatinib Pill|DRUG: Ketoconazole Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bowel Sounds Analysis in Paediatric Inflammatory Bowel Disease: Relationship With wPCDAI
Status: ACTIVE_NOT_RECRUITING
Conditions: Bowel Sounds|Intestinal Inflammation|Crohn Disease
Interventions: OTHER: Abdominal auscultation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Activated Recombinant Human Factor VII in Treatment of Bleeding in Patients Following Hematopoietic Stem Cell Transplantation
Status: TERMINATED
Conditions: Acquired Bleeding Disorder|Bleeding During/Following Surgery
Interventions: DRUG: standard therapy|DRUG: placebo|DRUG: activated recombinant human factor VII|DRUG: activated recombinant human factor VII
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Safety, Tolerability and Pharmacokinetics of QEV-817 Oral Suspension
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: Hydrocodone Bitartrate|DRUG: Doxapram Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Artificial Intelligence Supporting CAncer Patients Across Europe - the ASCAPE Project
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Prostate Cancer|Quality of Life|Survivorship|Toxicity
Interventions: OTHER: ASCAPE-based follow-up strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability and Immunogenicity of Two Doses of Adjuvanted Monovalent Influenza Vaccine Administered to Healthy Adult and Elderly Subjects
Status: COMPLETED
Conditions: Pandemic Influenza Disease
Interventions: BIOLOGICAL: Placebo (PL)|BIOLOGICAL: Trivalent influenza virus vaccine (TIV)|BIOLOGICAL: Adjuvanted monovalent influenza virus vaccine (aH5N1)|BIOLOGICAL: Adjuvanted trivalent influenza virus vaccine (aTIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: S0101 Gemcitabine and Irinotecan in Treating Patients With Metastatic or Recurrent Cancer of the Esophagus
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: taVNS for FRNS in Children
Status: RECRUITING
Conditions: Nephrotic Syndrome in Children|Minimal Change Disease|Focal Segmental Glomerulosclerosis
Interventions: DEVICE: Transcutaneous auricular vagus nerve stimulation|DEVICE: Sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gender, Obesity, C-Reactive Protein, and Oxidative Stress
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Vitamin C|DIETARY_SUPPLEMENT: Vitamin E|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Feasibility of Nurse-led Retinal Imaging for Retinopathy of Prematurity Screening Employing the Optos California
Status: COMPLETED
Conditions: Retinopathy of Prematurity
Interventions: DIAGNOSTIC_TEST: Nurse led screening with Optos ultra-widefield retinal-imaging device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nasal Noninvasive NAVA in the Very Low Birth Weight Infant
Status: COMPLETED
Conditions: Inadequate; Pulmonary Ventilation, Newborn|Infant, Very Low Birth Weight
Interventions: DEVICE: Nasal NIV-NAVA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacogenomics Study for Breast Cancer Patients Undergoing Adjuvant Chemotherapy With Doxorubicin (A)/Cyclophosphamide ©) and/or Weekly Paclitaxel
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: cyclophosphamide|DRUG: doxorubicin|DRUG: paclitaxel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EffCaMgCit to Prevent Mineral Metabolism and Renal Complications of Chronic PPI Therapy
Status: RECRUITING
Conditions: Osteoporosis|Hypomagnesemia
Interventions: DRUG: EffCaMgCit|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NMDA Enhancer for the Treatment of Mild Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: DAOI-A group|DRUG: DAOI-B group|DRUG: DAOI-C group|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Antroquinonol in Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Antroquinonol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Psychoeducation Program Given to Behcet's Patients in the Context of the Roy Adaptation Model
Status: COMPLETED
Conditions: Psychoeducation|Nursing Caries|Behcet Syndrome
Interventions: BEHAVIORAL: psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Esketamine in Microelectrode Recording-guided Subthalamic Deep-Brain Stimulation for Parkinson's Disease
Status: RECRUITING
Conditions: PD - Parkinson's Disease|Deep Brain Stimulation|Esketamine
Interventions: DRUG: esketamine|DRUG: normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Water Exchange Method on Single-balloon Enteroscopy
Status: COMPLETED
Conditions: Single Balloon Enteroscopy
Interventions: PROCEDURE: water exchange single balloon enteroscopy|PROCEDURE: CO2 insufflation single balloon enteroscopy|OTHER: Procedural Requirements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Study and Economic Analysis of an Intraoperative Navigation System for Total Hip Arthroplasty
Status: NOT_YET_RECRUITING
Conditions: Total Hip Arthroplasty
Interventions: PROCEDURE: Intra-Operative Device for THA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Severe Necrotizing Enterocolitis in Preterm Newborns <1500g Using Probiotics
Status: COMPLETED
Conditions: Infectious Diseases
Interventions: DIETARY_SUPPLEMENT: probiotics Lactobacillus acidophilus boucardii
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study In Patients With Irritable Bowel Syndrome To Measure Hormone Response After Dosing With GW876008 And Gsk561679
Status: WITHDRAWN
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: GW876008 and GSK561679
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PK PD Study of IDA and Azithromycin for NTDs ( ComboNTDs )
Status: COMPLETED
Conditions: Lymphatic Filariasis|Yaws|Trauma
Interventions: DRUG: Azithromycin|DRUG: Albendazole|DRUG: Ivermectin|DRUG: Diethylcarbamazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ticagrelor in Comparison to Prasugrel for Early Inhibition of Platelet Reactivity in Patients With ST-elevation Myocardial Infarction (STEMI), Undergoing Primary Percutaneous Coronary Intervention (PCI)
Status: COMPLETED
Conditions: Platelet Reactivity
Interventions: DRUG: Prasugrel|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation of the Auditory Space for Bilateral Cochlear Implant Users : a Feasibility Study
Status: COMPLETED
Conditions: Cochlear Prosthesis Implantation
Interventions: BEHAVIORAL: Rehabilitation protocol with visual-auditory feedback|BEHAVIORAL: Rehabilitation protocol with visual feedback|BEHAVIORAL: SPHERE protocol|BEHAVIORAL: French Matrix Test|BEHAVIORAL: Speech Spatial and Qualities of Hearing Scale (SSQ15) questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Resistant Maltodextrin Supplementation: Gastrointestinal Health
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: 15 g RMD|DIETARY_SUPPLEMENT: 25 g RMD|DIETARY_SUPPLEMENT: 0 g RMD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: IKANOS: Breztri Maintenance Versus Any Non-Triple Inhaled Therapy After Hospitalization for a COPD Exacerbation in the US
Status: WITHDRAWN
Conditions: COPD
Interventions: DRUG: Budesonide/glycopyrrolate/formoterol fumarate (Breztri Aerosphere) 320 μg/18 μg/9.6 μg administered as two inhalations, twice daily.|OTHER: External Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azithromycin in Combination With Chloroquine Versus Chloroquine in the Eradication of Asymptomatic Plasmodium Falciparum
Status: TERMINATED
Conditions: Malaria, Falciparum
Interventions: DRUG: Azithromycin/Chloroquine|DRUG: Chloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Taxi STEP (Social Networks, Technology, and Exercise Through Pedometers)
Status: ACTIVE_NOT_RECRUITING
Conditions: Physical Conditioning
Interventions: OTHER: Health Fair|OTHER: Pedometer|OTHER: Text Messaging|OTHER: Social Network Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Beneficial Role of Percutaneous Coronary Intervention Over Optimal Medical Therapy in Elderly Patients With Coronary Artery Disease
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Everolimus Eluting Stent or Zotalolimus Eluting Stent|DRUG: ARB, CCB, ACE-inhibitor, statin, Nitrate, Antiplate etc.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MAP for Coaches: Translating Sports Injury Prevention Knowledge to Youth Sport Coaches
Status: RECRUITING
Conditions: Knowledge, Attitudes, Practice
Interventions: BEHAVIORAL: MAP for Coaches - Complete Course|BEHAVIORAL: Map for Coaches - Overview
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Selonsertib in Adults With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH)
Status: TERMINATED
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: SEL|DRUG: Placebo to match SEL 6 mg|DRUG: Placebo to match SEL 18 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Artificial Intelligence Technology in Detecting Number of Root Canals in Human Mandibular First Molars Obturated and Indicated for Retreatment: Diagnostic Accuracy Experimental Study
Status: COMPLETED
Conditions: Missed Canals
Interventions: DIAGNOSTIC_TEST: CBCT|DIAGNOSTIC_TEST: clinical examination under dental operating microscope|DIAGNOSTIC_TEST: canal detection AI software (diagnocat)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Investigating the Dose Response of an Almond-enriched Diet on Optimizing HDL-C in a Population With Hypercholesterolemia
Status: COMPLETED
Conditions: HDL-C|Hypercholesterolemia
Interventions: OTHER: Almond-enriched diet - 1.5 oz|OTHER: Almond-enriched diet - 2.5 oz|OTHER: Control snack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Ephedrine Attenuates the Hemodynamic Responses of Propofol During Valve Surgery: A Dose Dependent Study
Status: COMPLETED
Conditions: Hypotension|Valve Surgery
Interventions: DRUG: Ephedrine|DRUG: Placebo|DRUG: Phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: How Frequently and in What Format Are Research Trial Results Disseminated to Participants (ResponseQT)
Status: COMPLETED
Conditions: Motivation
Interventions: BEHAVIORAL: Group A Reminder|BEHAVIORAL: Group B Reminder|BEHAVIORAL: Group C Reminder|BEHAVIORAL: Group D Reminder|BEHAVIORAL: Group E Reminder|BEHAVIORAL: Group F Reminder|BEHAVIORAL: Group G Reminder|BEHAVIORAL: Group H Reminder|BEHAVIORAL: Group I Reminder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cerebral Oximetry in Cardiac Surgery to Reduce Neurological Impairment and Hospital Length-of-stay
Status: COMPLETED
Conditions: Cardiac Surgery|Neural Injury|Cerebral Ischemia
Interventions: OTHER: Physiological
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Intranasal Nerve Growth Factor for Acute Ischemic Stroke
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Nerve Growth Factors|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Hemoperfusion With a Polymyxin B Membrane in Peritonitis With Septic Shock
Status: COMPLETED
Conditions: Peritonitis|Septic Shock
Interventions: DEVICE: standard therapy|DEVICE: hemoperfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ramucirumab, Trastuzumab and Paclitaxel in Patients With HER2-positive Recurrent/Metastatic Gastric Cancer (HER-RAM Study)
Status: UNKNOWN
Conditions: Recurrent/Metastatic Gastric Cancer
Interventions: DRUG: Trastuzumab + Ramucirumab + Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Scrotal Incision for Penile Prosthesis Implantation, Novel Technique.
Status: UNKNOWN
Conditions: Penile Prosthesis Infection|Penile Prosthesis; Complications, Infection or Inflammation
Interventions: PROCEDURE: transverse scrotal approach for PPI|PROCEDURE: penoscrotal approach for PPI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: How DHEA Supplements Affect Coagulation in Women Using Birth Control Pills
Status: COMPLETED
Conditions: Contraceptive Usage|Coagulation
Interventions: DIETARY_SUPPLEMENT: DHEA Oral Capsule|OTHER: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Neostigmine on the Recovery of Rocuronium: A Comparison Between Partial and TOF Ratio-Based Dose
Status: COMPLETED
Conditions: Muscle Relaxant|General Anesthesia
Interventions: DRUG: Dose of Neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exploratory/Proof of Principle Microbiota Study
Status: COMPLETED
Conditions: Fecal Microbiota
Interventions: OTHER: Amino acid based infant formula|OTHER: Extensively hydrolyzed casein infant formula|OTHER: Mother's own breast milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of OMS302 in Subjects Undergoing Intraocular Lens Replacement With Phacoemulsification
Status: COMPLETED
Conditions: Intraocular Lens Replacement
Interventions: DRUG: OMS302|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Abdominal Wall Nerve Blockade in Laparoscopic Surgery for Acute Appendicitis.
Status: COMPLETED
Conditions: Appendicitis
Interventions: DRUG: Ropivacaine|DRUG: Saline 9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the FemoSeal® Arterial Closure Device to Manual Compression After Coronary Angiography
Status: COMPLETED
Conditions: Coronary Angiography Via Femoral Artery Access
Interventions: DEVICE: FemoSeal®|OTHER: Manual compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Valproic Acid, Magnesium Sulphate, Rocuronium Requirement, Postoperative Analgesia
Status: UNKNOWN
Conditions: Cerebral Aneurysm
Interventions: DRUG: Magnesium Sulfate|DRUG: 0.9% saline|DRUG: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study by Electroencephalography of the Link Between the Lack of Self-compassion and the Disorder of Empathy in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DEVICE: Electroencephalogram
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Oxytocin and Cognitive Control in Adult ADHD
Status: COMPLETED
Conditions: Attention Deficit/Hyperactivity Disorder
Interventions: DRUG: Oxytocin nasal spray|DRUG: Placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety of and Immune Response to an HIV-1 Vaccine (ALVAC-HIV vCP1521) in Infants Born to HIV Infected Mothers
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: ALVAC-HIV vCP1521|BIOLOGICAL: ALVAC HIV-1 vCP1521
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Paroxetine-CR to Treat Post-Traumatic Stress Disorder (PTSD) Symptomatic After Initial Exposure Therapy
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: DRUG: Cognitive-behavioral therapy and paroxetine-CR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Luveltamab Tazevibulin in Adults With Advanced or Metastatic Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer|Lung Cancer Metastatic|Lung Cancer, Nonsmall Cell|Lung Cancer Non-Small Cell Stage IIIB|Lung Cancer Non-small Cell Stage IV|Lung Cancer, Non-small Cell
Interventions: DRUG: Luveltamab tazevibulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Conjugated Linoleic Acid Alone and in Conjunction With Vitamin E in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Tonalin SG1000T FFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Investigate the Efficacy, Safety, and Tolerability of DFV890 and MAS825 for Inflammatory Marker Reduction in Adult Participants With Coronary Heart Disease and Clonal Hematopoiesis of Indeterminate Potential (CHIP)
Status: RECRUITING
Conditions: Coronary Heart Disease|Clonal Hematopoiesis of Indeterminate Potential (CHIP)
Interventions: DRUG: MAS825|DRUG: MAS825 Placebo|DRUG: DFV890|DRUG: DFV890 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate Safety and Tolerability of OratecanTM in Patients With Advanced Solid Malignancies
Status: COMPLETED
Conditions: Advanced Solid Malignancies
Interventions: DRUG: HM30181AK tablet + Irinotecan tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Remote Ischemic Preconditioning in Patient Undergoing Cardiac Bypass Surgery
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: PROCEDURE: Remote ischemic preconditioning|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Metabolism of Methylphenidate and Enalapril Based on CES1 Genotype
Status: COMPLETED
Conditions: Carboxylesterase 1 (CES1) Genotype|CES1 Activity
Interventions: DRUG: Methylphenidate|DRUG: Enalapril
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Periodontal Treatment With Diode Laser in the Patients With Diabetes Melitus
Status: COMPLETED
Conditions: Diabetes Mellitus|Periodontal Disease
Interventions: DEVICE: Laser group|DEVICE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lapatinib in Treating Patients With Recurrent and/or Metastatic Adenoid Cystic Cancer or Other Salivary Gland Cancers
Status: COMPLETED
Conditions: High-grade Salivary Gland Carcinoma|High-grade Salivary Gland Mucoepidermoid Carcinoma|Low-grade Salivary Gland Carcinoma|Low-grade Salivary Gland Mucoepidermoid Carcinoma|Recurrent Adenoid Cystic Carcinoma of the Oral Cavity|Recurrent Salivary Gland Cancer|Salivary Gland Acinic Cell Tumor|Salivary Gland Adenocarcinoma|Salivary Gland Adenoid Cystic Carcinoma|Salivary Gland Malignant Mixed Cell Type Tumor
Interventions: DRUG: lapatinib ditosylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Acetylcholine and Attention on Visual Spatial Representations in the Brain
Status: COMPLETED
Conditions: Visual Perception|Attention|Information Processing|Cholinergic System
Interventions: DRUG: Donepzil|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Temozolomide and Thalidomide in Treating Patients With Brain Metastases Secondary to Melanoma
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage IV Melanoma|Tumors Metastatic to Brain
Interventions: DRUG: temozolomide|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Contrast 4DCT to Detect Pulmonary Thromboembolic Events
Status: COMPLETED
Conditions: Pulmonary Thromboembolisms|Pulmonary Embolism
Interventions: DEVICE: 4DCT and SPECT/CT|DEVICE: 4DCT with BiPAP and SPECT/CT|DEVICE: 4DCT with CTA in suspected PE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: WEUSKOP6416: Evaluating Pneumonia in Chronic Obstructive Pulmonary Disease (COPD) Subjects
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: New users of ADVAIR DISKUS, ADVAIR HFA (ICS) - containing medications|DRUG: New users of FLOVENT DISKUS, FLVENT HFA (long-acting bronchodilators (LABD))
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Demonstrate the Relative Bioavailability Study of Promethazine HCl 50 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Allergy
Interventions: DRUG: Promethazine HCl 50 mg Tablets (Sandoz, Inc)|DRUG: Phenergan (Promethazine HCl) 50 mg Tablets (Wyeth Laboratories)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicentre Study to Evaluate the Safety and Efficacy of AD 923 in Comparison to MSIR for the Treatment of CBP in Subjects
Status: TERMINATED
Conditions: Cancer|Pain
Interventions: DRUG: AD 923
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Performance of TMS-thermometer With Standard Esophageal or Urine Bladder Thermometer
Status: UNKNOWN
Conditions: to Evaluate the Performance of the TMS Thermometer and|Improve Its Algorithm
Interventions: DEVICE: Intraoperative temperature measurement by TMS thermometer|DEVICE: Esophageal or urinary bladder temperature measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of ATRA Activity in Combination With Anastrozole in Pre-operative Phase of Operable Early Breast Cancer
Status: RECRUITING
Conditions: Breast Neoplasm Female
Interventions: DRUG: all-trans retinoic acid|DRUG: Anastrozole 1mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selective Retina Therapy With 'R:GEN' in Patients With Central Serous Chorioretinopathy
Status: COMPLETED
Conditions: Central Serous Chorioretinopathy
Interventions: DEVICE: R:GEN Selective Retina Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT