pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Assessment of Serological Techniques for Screening Patients Regarding COVID-19-COVID-SER
Status: ACTIVE_NOT_RECRUITING
Conditions: CoV2 Positive Caregivers
Interventions: DIAGNOSTIC_TEST: Serological tests will be applied on patients blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Determination of In-vivo Plasma AA Appearance From Plant Protein Fibre Products
Status: COMPLETED
Conditions: Aging|Undernutrition|Appetite Loss|Age-Related Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Net peripheral AA appearance following ingestion of 3 selected PPF products compared to whey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Single Dose and Multiple Dose Escalation Trial of an Oral Formulation of MRX-4
Status: COMPLETED
Conditions: Safety
Interventions: DRUG: Oral single doses of MRX-4|DRUG: Oral multiple doses of MRX-4|DRUG: MRX-4 co-administered with omeprazole|DRUG: Oral single doses of placebo|DRUG: Oral multiple doses of placebo|DRUG: Placebo co-administered with omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Efficacy of Enteral Nutrition in Fill of the Treatment Blank Period of the Postoperative Maintain Remission Medication for Crohn's Disease (CD)
Status: UNKNOWN
Conditions: Crohn's Disease
Interventions: DRUG: azathioprine+enteral nutrition|DRUG: Azathioprine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Goals of Care: A Nursing Home Trial of Decision Support for Advanced Dementia
Status: COMPLETED
Conditions: Dementia
Interventions: BEHAVIORAL: Goals of care decision support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Long-Term Study of Elafibranor in Adult Participants With Primary Biliary Cholangitis
Status: RECRUITING
Conditions: Primary Biliary Cholangitis (PBC)
Interventions: DRUG: Elafibranor|OTHER: Matched 80 mg placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CytoreductiveSurgery & HIPEC W/Gemcitabine+Chemotherapy W/Dacarbazine in Uterine Leiomyosarcoma
Status: RECRUITING
Conditions: LMS - Leiomyosarcoma|Uterine Leiomyosarcoma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Effectiveness of a Self-regulation Program to Treat Pediatric Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: CAAT: Appetite Awareness|BEHAVIORAL: CRST: Volcravo|BEHAVIORAL: Combined CAAT and CRST program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Neurocognitive and Metabolic Effects of Fructose, Glucose, High Fructose Corn Syrup and Sucrose at Normal Population Consumed Levels in Adults Ages 20-60 Years Old
Status: COMPLETED
Conditions: Conditions: None. Focus: Understanding the Obesogenic Potential of Fructose Containing Sugars
Interventions: OTHER: Beverage Consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Changing Levels of Neurally Adjusted Ventilatory Assist (NAVA) in Newborns
Status: COMPLETED
Conditions: Newborn Morbidity
Interventions: DEVICE: NAVA level
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Family Promoting Positive Emotions Pilot Study
Status: COMPLETED
Conditions: Depression|Anhedonia|Stress|Depressive Disorder|Behavioral Symptoms|Mood Disorders|Mental Disorder|Mood Disturbance
Interventions: BEHAVIORAL: Family Promoting Positive Emotions (F-PPE)|BEHAVIORAL: Written Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Unicompartmental Knee Arthroplasty vs. High Tibial Osteotomy for Medial Knee Osteoarthritis (UNIKORN): a Study Protocol of a Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Unicompartmental knee arthroplasty|PROCEDURE: High tibial osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postacute Sarcopenia: Supplementation With β-hydroxyMethylbutyrate After Resistance Training
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: β-hydroxymethylbutyrate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Evaluating the Efficacy and Safety of IBI310 in Combination With Sintilimab, for Neoadjuvant Treatment of MSI-H/dMMR Resectable Colon Cancer
Status: RECRUITING
Conditions: MSI-H
Interventions: DRUG: Sintilimab|DRUG: IBI310&Sintilimab|PROCEDURE: Radical surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers for Prediction of Analgesic Efficacy in Knee OA.
Status: COMPLETED
Conditions: Knee, Osteoarthritis (OA)|Biomarkers for Prediction of OA Treatment Efficacy
Interventions: DRUG: Duloxetine 60mg|DRUG: Etoricoxib 60 mg|DRUG: omeprazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nifedipine Bioavailability Study With Oral Single Doses Under Fasting and Fed Conditions
Status: COMPLETED
Conditions: Bioavailability, Therapeutical Indication Not Studied
Interventions: DRUG: Nifedipine (Gen-nifedipine extended release, previously referred to as Gen-Nifedipine XL)|DRUG: Nifedipine (Bayer Healthcare AG manufactured as Adalat® XL®, Adalat® LA, Adalat® Crono, Adalat® OROS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
Status: RECRUITING
Conditions: Mitral Valve Regurgitation
Interventions: DEVICE: Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)|DEVICE: Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-First Progression Use of Bevacizumab in Metastatic Colorectal Cancer (mCRC)
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Bevacizumab (Avastin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standardization of Multi-modal Tumor Ablation Therapy System
Status: UNKNOWN
Conditions: Liver Neoplasms|Ablation Techniques|Cryoablation|Safety|Treatment Outcome|Neoplasm Metastasis|Clinical Trial
Interventions: DEVICE: Multi-modal Precision Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retracting the Esophagus During AF Ablation
Status: UNKNOWN
Conditions: Atrial Fibrillation|Esophageal Fistula|Cardiac Arrhythmia
Interventions: DEVICE: Esophageal Stylet - EsoSure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Financial Burden Assessment in Patients With Stage I-III Colon or Rectal Cancer Undergoing Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage I Colon Cancer AJCC v8|Stage I Rectal Cancer AJCC v8|Stage II Colon Cancer AJCC v8|Stage II Rectal Cancer AJCC v8|Stage IIA Colon Cancer AJCC v8|Stage IIA Rectal Cancer AJCC v8|Stage IIB Colon Cancer AJCC v8|Stage IIB Rectal Cancer AJCC v8|Stage IIC Colon Cancer AJCC v8|Stage IIC Rectal Cancer AJCC v8|Stage III Colon Cancer AJCC v8|Stage III Rectal Cancer AJCC v8|Stage IIIA Colon Cancer AJCC v8|Stage IIIA Rectal Cancer AJCC v8|Stage IIIB Colon Cancer AJCC v8|Stage IIIB Rectal Cancer AJCC v8|Stage IIIC Colon Cancer AJCC v8|Stage IIIC Rectal Cancer AJCC v8
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optimal Timing of Intrauterine Insemination (IUI) When Utilizing Superovulation Combined With GnRH Antagonists
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: Intrauterine Insemination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Safety of Bile Duct Clearance by Transcystic Sphincter of Oddi Balloon Dilatation
Status: COMPLETED
Conditions: Cholecystolithiasis|Choledocholithiasis|Surgery
Interventions: PROCEDURE: Papillary ballon dilatation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vorinostat and Concurrent Whole Brain Radiotherapy for Brain Metastasis
Status: TERMINATED
Conditions: Brain Metastasis
Interventions: DRUG: Vorinostat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Placing the Implant Crown on the Implant on the Same Day as the Implant vs. 4 Weeks Later.
Status: RECRUITING
Conditions: Lower Molar Requiring Extraction
Interventions: PROCEDURE: Immediate Loading|PROCEDURE: Early Loading
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Safety of Metformin Versus Apple Cider Vinegar (ACV) in Prediabetics
Status: COMPLETED
Conditions: PreDiabetes
Interventions: DRUG: Metformin Hydrochloride (HCL)|DIETARY_SUPPLEMENT: Apple cider vinegar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Records for Alcohol Care Enhancement
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Use Disorder (AUD)
Interventions: BEHAVIORAL: Best Practice Advisory (BPA) and Population Health Management (PHM)|BEHAVIORAL: Best Practice Advisory (BPA) and Clinical Care Management (CCM)|BEHAVIORAL: Best Practice Advisory (BPA) and Population Health Management (PHM) and Clinical Care Management (CCM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Masseter Muscle Activity and Post-operative Pain in a Group of Egyptian Children Treated With Hall Technique Vs Modified Hall Technique
Status: UNKNOWN
Conditions: Masseter Muscle Activity
Interventions: DIAGNOSTIC_TEST: Modified Hall technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Regorafenib and Methotrexate in Treating Participants With Recurrent or Metastatic KRAS Mutated Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: KRAS Gene Mutation|Metastatic Malignant Neoplasm in the Brain|Recurrent Non-Small Cell Lung Carcinoma|Stage IV Non-Small Cell Lung Cancer AJCC v7
Interventions: DRUG: Methotrexate|OTHER: Pharmacokinetic Study|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omadacycline vs. Moxifloxacin for the Treatment of Community-Acquired Bacterial Pneumonia
Status: COMPLETED
Conditions: Community-acquired Pneumonia|Bacterial Pneumonia
Interventions: DRUG: Omadacycline|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Oxymorphone Hydrochloride 40 mg Extended Release Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: oxymorphone hydrochloride|DRUG: Opana
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phacotrabeculectomy With Collagen Matrix Implant (Ologen®) Versus Mitomycin C
Status: COMPLETED
Conditions: Glaucoma|Cataract|Wound Heal
Interventions: DEVICE: Ologen|PROCEDURE: Phacotrabeculectomy|DRUG: Mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ivermectin Treatment Efficacy in Covid-19 High Risk Patients
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Ivermectin 0.4mg/kg/day for 5 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Testosterone Cream For Atrophic Vaginitis in Women Taking Aromatase Inhibitors for Breast Cancer.
Status: SUSPENDED
Conditions: Vaginitis|Dyspareunia|Breast Neoplasms
Interventions: DRUG: Testosterone propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measuring the Concurrent Validity of the Upper Limb Use Ratio With Accelerometers in an Ecological Situation After Stroke.
Status: NOT_YET_RECRUITING
Conditions: Cerebrovascular Accident
Interventions: BEHAVIORAL: Objective assessment of upper limb use during activities in ecological situation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Inhaled Imatinib Pulmonary Arterial Hypertension Clinical Trial - Follow Up Long Term Extension (IMPAHCT-FUL)
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: AV-101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Chemotherapy in Combination With Tislelizumab in Lymph Node-Positive Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical DHEA Against Vaginal Atrophy
Status: COMPLETED
Conditions: Vaginal Atrophy
Interventions: DRUG: Placebo|DRUG: DHEA (0.25%)|DRUG: DHEA (0.5%)|DRUG: DHEA (1.0%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SGLT-2 and DPP-4 Inhibition, Subclinical Inflammation of the Genito-urinary Tract and Risk of Infections.
Status: UNKNOWN
Conditions: Type 2 Diabetes|Urinary Tract Infections
Interventions: DRUG: Empagliflozin / Linagliptin or Dapagliflozin/Saxagliptin Pill|DRUG: Empagliflozin or Dapagliflozin Pill
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Using Practice Facilitation and Operationalizing Referral Information Technology to Increase DSMES Utilization
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes
Interventions: OTHER: UP FOR IT - practice facilitation|OTHER: UP FOR IT - health information technology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Randomised Single Centre Study to Compare the Long-term Wear Characteristics of Marathon™ and Enduron™ Polyethylene Cup Liners in Primary Total Hip Replacement
Status: COMPLETED
Conditions: Osteoarthritis|Post-traumatic Arthritis|Collagen Disorders|Avascular Necrosis|Traumatic Femoral Fractures|Nonunion of Femoral Fractures|Congenital Hip Dysplasia|Slipped Capital Femoral Epiphysis
Interventions: DEVICE: Marathon™|DEVICE: Enduron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Oxidative Stress in Appendectomy - Open Versus Laparoscopic in Childhood and Adolescence
Status: UNKNOWN
Conditions: Appendicitis Acute
Interventions: DIAGNOSTIC_TEST: Initial serum malondialdehyde level|DIAGNOSTIC_TEST: Final serum malondialdehyde level|DIAGNOSTIC_TEST: Initial differential white blood cell count|DIAGNOSTIC_TEST: Final differential white blood cell count|DIAGNOSTIC_TEST: Initial c-reactive protein serum level|DIAGNOSTIC_TEST: Final c-reactive protein serum level|DIAGNOSTIC_TEST: Initial VOC|DIAGNOSTIC_TEST: VOC 5min|DIAGNOSTIC_TEST: VOC 15min|DIAGNOSTIC_TEST: VOC 30min|DIAGNOSTIC_TEST: VOC 45min|DIAGNOSTIC_TEST: Final VOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Attentional Control Training for Treating Alcohol Use Disorder
Status: UNKNOWN
Conditions: Alcohol Use Disorder (AUD)|Attentional Bias
Interventions: BEHAVIORAL: Attentional Control Training Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Immunogenicity, Safety and Tolerability of Quadrivalent Human Papillomavirus Vaccine (V501) in Chinese Girls Aged 9-19 Years and Young Women Aged 20-26 Years (V501-213)
Status: COMPLETED
Conditions: Prevention of HPV Types 16- and 18-related Cervical Cancer, Cervical Intraepithelial Neoplasia (CIN) 1/2/3, and Cervical Adenocarcinoma in Situ
Interventions: BIOLOGICAL: V501
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy Study of Intramuscular or Intracoronary Injection of Autologous Bone Marrow Cells to Treat Scarred Myocardium
Status: COMPLETED
Conditions: Myocardial Infarct|Bone Marrow Cells
Interventions: PROCEDURE: Control|PROCEDURE: Intramuscular administration of bone marrow cells|PROCEDURE: Intracoronary administration of bone marrow cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET and Recovery Following Revascularization (PARR 2)
Status: COMPLETED
Conditions: Coronary Artery Disease|Ventricular Dysfunction, Left
Interventions: PROCEDURE: Positron emission tomography: FDG viability imaging|OTHER: PET imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Potential Drug Interaction Study Between Vemircopan and Rosuvastatin, Metformin, Levonorgestrel/Ethinyl Estradiol-containing Oral Contraceptives, and Carbamazepine
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Vemircopan|DRUG: Rosuvastatin|DRUG: Metformin|DRUG: Levonorgestrel / Ethinyl Estradiol|DRUG: Carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pain Therapeutic Education and Hydrotherapy on Physical Function, Pain and Sleep of Women With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: Pain Education|OTHER: Hydrotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intracoronary Administration of Glucocorticoids as a Treatment Method for No-Glucocorticoid Treatment for No-Reflow in STEMI
Status: COMPLETED
Conditions: Ischemia-reperfusion Injury|No-reflow
Interventions: DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AFFINITY DUCHENNE: RGX-202 Gene Therapy in Participants With Duchenne Muscular Dystrophy (DMD)
Status: RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: GENETIC: RGX-202
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Application of M-charts and Microperimetry for the Assessment of Visual Function in Patients After Vitrectomy Due to the Full Thickness Macular Hole.
Status: COMPLETED
Conditions: Macular Holes|Microperymetry|Vitrectomy|M-charts
Interventions: DIAGNOSTIC_TEST: Microperymetry|DIAGNOSTIC_TEST: M-charts
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ivabradine Effects in Cardiogenic Shock Requiring Inotropic Support
Status: RECRUITING
Conditions: Heart Failure|Cardiogenic Shock|Ischemic Heart Disease
Interventions: DRUG: Ivabradine 7.5Mg Tab|DRUG: DOBUTamine Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Abemaciclib (LY2835219) Alone or in Combination With Other Agents in Participants With Previously Treated Pancreatic Ductal Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Abemaciclib|DRUG: LY3023414|DRUG: Gemcitabine|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Transcutaneous Electrical Nerve Stimulation for Overactive Bladder
Status: TERMINATED
Conditions: Urge Incontinence|Overactive Bladder
Interventions: DEVICE: Transcutaneous Electrical Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effect of Exercise on Disease Activity and Cardiovascular Risk Factors in Patients With Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondyliti
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recurrence and Patient Satisfaction After Laparoscopic Hernia Repair With Intraperitoneal Onlay-mesh (IPOM)
Status: COMPLETED
Conditions: Ventral Hernia|Recurrent Ventral Hernia
Interventions: PROCEDURE: hernia gap closure|PROCEDURE: extracorporal suturing of gap
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pain and Quality of Life After Inguinal Hernia Repair: Laparoscopic Versus Open Repair.
Status: RECRUITING
Conditions: Hernia, Inguinal
Interventions: PROCEDURE: Laparoscopic Transabdominal Preperitoneal Inguinal Hernia Repair (TAPP repair)|PROCEDURE: Open Inguinal Hernia Repair (Lichtenstein repair)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Afatinib With CT and RT for EGFR-Mutant NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Afatinib|RADIATION: Radiation|DRUG: Cisplatin|DRUG: Pemetrexed|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study Using Consecutive Intravenous Depacon With Oral Depakote ER for the Treatment of Cluster Headaches.
Status: COMPLETED
Conditions: Cluster Headache
Interventions: DRUG: Depacon IV and Depakote ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sensible Medical Innovations Lung fLuid Status Monitor Allows rEducing Readmission Rate of Heart Failure Patients
Status: TERMINATED
Conditions: Heart Failure
Interventions: DEVICE: Remote Dielectric Sensing (ReDS) Wearable System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed Dose Combination in the Treatment of Hepatitis C Virus (HCV) Infection in Pediatric Participants Undergoing Cancer Chemotherapy
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: LDV/SOF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Efficacy, and Safety of Topical Therapy and Etanercept in Subjects With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: 1=Etanercept|DRUG: 2=Clobetasol propionate foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab, Erlotinib, and Capecitabine for Locally Advanced Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DRUG: Bevacizumab|DRUG: Capecitabine|DRUG: Erlotinib|RADIATION: Radiation Therapy|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety and Efficacy of NCX 4251 Ophthalmic Suspension for the Treatment of Blepharitis
Status: COMPLETED
Conditions: Blepharitis
Interventions: DRUG: NCX 4251|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Intervention of Eriomin Associated With Metformin in the Control of Hyperglycemia in Pre-Diabetic Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Pre-diabetes
Interventions: DIETARY_SUPPLEMENT: Eriomin|DIETARY_SUPPLEMENT: Washout|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Diabetes Risk Factors in Persons With Schizophrenia or Bipolar Disorder by Switching to Ziprasidone
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Bipolar Disorder
Interventions: DRUG: ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of DDAVP Combined With TXA on the Blood Loss and Transfusion Need During and After Scoliosis Correction Surgery
Status: UNKNOWN
Conditions: Idiopathic Scoliosis
Interventions: DRUG: tranexamic acid and sodium chloride injection|DRUG: normal saline|DRUG: desmopressin acetate injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of SPR001 in Subjects With Classic Congenital Adrenal Hyperplasia
Status: COMPLETED
Conditions: Congenital Adrenal Hyperplasia|CAH - Congenital Adrenal Hyperplasia|CAH - 21-Hydroxylase Deficiency
Interventions: DRUG: SPR001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diet as Essential Therapy (DIET) for Inflammatory Bowel Disease
Status: UNKNOWN
Conditions: Crohn Disease
Interventions: DIETARY_SUPPLEMENT: Diet 1|DIETARY_SUPPLEMENT: Diet 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of Posture Correction Girdle for Adolescents With Early Scoliosis
Status: UNKNOWN
Conditions: Adolescent Idiopathic Scoliosis
Interventions: DEVICE: Posture correction girdle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D for Polycystic Ovary Syndrome Clomiphene Resistant Women
Status: COMPLETED
Conditions: PCOS|Vitamin D Deficiency
Interventions: DRUG: Vit D|DRUG: Metformin|DRUG: Clomiphene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preterm Premature Rupture of Fetal Membranes: Cervical Ultrasound and Biological Markers to Diagnose Prematurity (RECHOBIOL)
Status: UNKNOWN
Conditions: Premature Rupture of Membrane
Interventions: DIAGNOSTIC_TEST: Vaginal secretions collection|DIAGNOSTIC_TEST: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Efficacy of Early Administration of Convalescent Plasma Among COVID-19 Cases in Egypt
Status: COMPLETED
Conditions: Convalescent Plasma|Covid19|Immunoglobulins|Plasma|Egypt
Interventions: BIOLOGICAL: Convalescent Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effort During Resistance Training in Type 2 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Type2 Diabetes Mellitus
Interventions: BEHAVIORAL: High-effort resistance exercise training|BEHAVIORAL: Low-effort resistance exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improvement of Cardiovascular Function After Bronchoscopic Lung Volume Reduction Using Endobronchial Valves
Status: UNKNOWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DIAGNOSTIC_TEST: Flow Mediated Dilation (FMD) measurement|OTHER: Blood pressure, pulse and blood oxygen saturation measurement|OTHER: ST George Respiratory Questionnaire|OTHER: Physical activity level (PAL) measurement|BIOLOGICAL: Withdrawal of a blood sample|PROCEDURE: Immediate Bronchoscopic Lung Volume Reduction|PROCEDURE: Delayed Bronchoscopic Lung Volume Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Anti-PD-1/PD-L1 Combined With Anti-angiogenic Agents as First-line Treatment for Unresectable HCC
Status: RECRUITING
Conditions: Unresectable Hepatocellular Carcinoma
Interventions: DRUG: Adebrelimab plus Apatinib|DRUG: Adebrelimab plus Bevacizumab|DRUG: Camrelizumab plus Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasopharyngeal Airway Guide Nasogastric Tube Placement
Status: COMPLETED
Conditions: Nasogastric Tube|Nasopharyngeal Airway|Anesthesia, General
Interventions: PROCEDURE: With nasopharyngeal airway|PROCEDURE: Without nasopharyngeal airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Integration of Minimal Invasive Cardiopulmonary Bypass System and the Research of Its Blood Compatibility
Status: UNKNOWN
Conditions: Cardiopulmonary Bypass|Cardiac Surgery
Interventions: DEVICE: minimal invasive cardiopulmonary bypass (MICPB) system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: BXCL701 Phase 1 R/R Acute Myeloid Leukemia or Myelodysplastic Syndrome
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome With Excess Blasts-2
Interventions: DRUG: BXCL701
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAPABLE Transitions: A Home Health-Based Intervention for the Hospital or Post-Acute Care Facility-to-Home Transition
Status: COMPLETED
Conditions: Care Transitions|Dementia
Interventions: BEHAVIORAL: CAPABLE Transitions|BEHAVIORAL: Home Health Agency Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Prospective Study to Collect High-Quality Documentation of Bleeds, Health-Related Quality of Life (HRQoL), and Safety Outcomes in Patients With Hemophilia A Treated With Standard-of-Care Treatment
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: Bypassing Agents|DRUG: FVIII Replacement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analgesia After Total Knee Arthroplasty: Peri-Articular Injection Versus Epidural + Femoral Nerve Blockade
Status: COMPLETED
Conditions: Readiness to Discharge
Interventions: PROCEDURE: Peri-Articular Injection|PROCEDURE: Epidural Pathway (PCEA+FNB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor, Adult|Cancer|Neoplasms|Sarcoma|Sarcoma,Soft Tissue|Chondrosarcoma
Interventions: BIOLOGICAL: AdAPT-001|DRUG: Checkpoint Inhibitor, Immune
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic Intervention With Elderly Subjects
Status: COMPLETED
Conditions: Intestinal C. Difficile
Interventions: DIETARY_SUPPLEMENT: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin) in Participants With Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Farletuzumab Ecteribulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune and Metabolic Effects of Vitamin D Supplementation in Healthy Humans
Status: COMPLETED
Conditions: Healthy Humans
Interventions: DRUG: Cholecalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Bile Acids in Patients With Peroxisomal Disorders
Status: TERMINATED
Conditions: Infantile Refsum's Disease|Zellweger Syndrome|Bifunctional Enzyme Deficiency|Adrenoleukodystrophy
Interventions: DRUG: chenodeoxycholic acid|DRUG: cholic acid|DRUG: ursodiol
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic and Pharmacokinetic Variability of a Basal Insulin (0000-168)
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: Isoglycemic Clamp|DRUG: Comparator: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurocognitive Outcome of Bilateral or Unilateral Hippocampal Avoidance WBRT With Memantine for Brain Metastases
Status: RECRUITING
Conditions: Metastatic Malignant Neoplasm to Brain
Interventions: RADIATION: Conformal Whole Brain Radiotherapy with Unilateral Hippocampal Avoidance|RADIATION: Conformal Whole Brain Radiotherapy with Bilateral Hippocampal Avoidance|DRUG: Memantine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of Low Dose Psilocybin
Status: RECRUITING
Conditions: Demoralization
Interventions: DRUG: Psilocybin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CD19/CD22-Dual-STAR-T for Patients With B Cell Acute Leukemia(B-ALL)
Status: TERMINATED
Conditions: Refractory and Relapsed B Cell Acute Leukemia
Interventions: BIOLOGICAL: CD19/CD22-Dual-STAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effects of Multiple Study Drug Regimens in Subjects With Newly Diagnosed Locally Advanced Head and Neck Squamous Cell Carcinoma
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DRUG: ABBV-181|DRUG: ABBV-368|DRUG: ABBV-927|DRUG: ABBV-927
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Range Finding Study of Lenalidomide in Non-5q Chromosome Deletion in Low and Intermediate Risk Myelodysplastic Syndrome (MDS) Patients
Status: TERMINATED
Conditions: Myelodysplastic Syndrome|MDS|Low to Intermediate-1 MDS|Non-deletion 5q
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy of Melanoma With Tumor Antigen RNA and Small Inhibitory RNA Transfected Autologous Dendritic Cells
Status: COMPLETED
Conditions: Metastatic Melanoma|Absence of CNS Metastases
Interventions: BIOLOGICAL: Proteasome siRNA and tumor antigen RNA-transfected dendritic cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Carboplatin, Weekly Abraxane and Trastuzumab in HER2+ Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Cohort 1 neo-adjuvant|DRUG: Cohort 2 neo-adjuvant|DRUG: Cohort 1 adjuvant|DRUG: Cohort 2 adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on Third-line Treatment of Advanced Duodenal Adenocarcinoma by Fuquinitinib Combined With Sindillimab
Status: NOT_YET_RECRUITING
Conditions: Third-line Treatment|Dvanced Duodenal Adenocarcinoma|Furquinelone Combined With Sintilimab
Interventions: DRUG: furquimatinib and sintilimab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Peginesatide for the Treatment of Anemia in Participants With Chronic Renal Failure Not on Dialysis
Status: COMPLETED
Conditions: Chronic Renal Failure|Chronic Kidney Disease|Anemia
Interventions: DRUG: peginesatide|DRUG: peginesatide|DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Congestive Heart Failure Adherence Redesign Trial
Status: COMPLETED
Conditions: Heart Failure, Congestive|Cardiovascular Diseases|Heart Diseases
Interventions: BEHAVIORAL: Enhanced Training|BEHAVIORAL: Enhanced Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Infigratinib Before Surgery for the Treatment of Upper Tract Urothelial Cancer
Status: COMPLETED
Conditions: Renal Pelvis and Ureter Urothelial Carcinoma
Interventions: DRUG: Infigratinib|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|PROCEDURE: Surgical Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rocamed Urethral Device (RUD) and Urinary Retention in Males
Status: COMPLETED
Conditions: Urinary Retention
Interventions: DEVICE: Exime is the name of the single use temporary prostatic stent used instead of the Foley catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Drug-drug Interactions (DDIs) of GP681 With Rosuvastatin, Digoxin, Itraconazole, Oseltamivir in Chinese Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: GP681|DRUG: Rosuvastatin|DRUG: Digoxin|DRUG: Itraconazole|DRUG: Oseltamivir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tomosynthesis (TS) Versus Ultrasonography (US) in Women With Dense Breast
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DEVICE: 3D mammography (Tomosynthesis)|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Open-label Study to Evaluate the Efficacy and Safety of Fespixon Cream for the Treatment of Pressure Injury in Sacrum and Greater Trochanter Wound
Status: TERMINATED
Conditions: Pressure Injury Stage 2
Interventions: DRUG: Fespixon Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nanoliposomal Irinotecan (Nal-IRI, ONIVYDE®) in Combination With TAS-102 (LONSURF®) in Refractory Solid Tumors
Status: COMPLETED
Conditions: Refractory Solid Tumors
Interventions: DRUG: Nanoliposomal Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Estimate Efficacy of Combining Dostarlimab and Niraparib in Relapsed EOC After Treatment With PARPi
Status: NOT_YET_RECRUITING
Conditions: Recurrent Ovarian Cancer|Recurrent Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: DRUG: Niraparib|DRUG: Dostarlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Symbiotic in the Reduction of Acute Radiation Proctitis Symptoms
Status: COMPLETED
Conditions: Radiation Proctitis|Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: Symbiotic|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Tick-borne Encephalitis and Positive Borrelial Antibodies
Status: UNKNOWN
Conditions: Tick-borne Encephalitis
Interventions: DRUG: Doxycycline|DRUG: Symptomatic therapy|OTHER: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Examine the Toxicity of Allogeneic Stem Cell Transplantation for Relapsed or Therapy Refractory Ewing Sarcoma
Status: WITHDRAWN
Conditions: Ewing Sarcoma
Interventions: BIOLOGICAL: allogeneic stem cell transplantation|DRUG: Clyclophosphamide|DRUG: Fludarabina|DRUG: Busulfan|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact on Hepatic Recurrence After Adjuvant Chemotherapy With Intraarterial Infusion of Idarubicin-Lipiodol
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: percutaneous destruction of the tumor + Idarubicin-Lipiodol treatment|PROCEDURE: Percutaneous destruction of the tumor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ERB-B4 After Treatment With HDAC Inhibitor in ER+ Tamoxifen Refractory Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: Panobinostat (LBH589)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: THE EFFECT OF CHIROPRACTIC THORACIC MANIPULATION ON PAIN, DEPRESSION, SLEEP AND QUALITY OF LIFE IN PATIENTS WITH FIBROMYALGIA
Status: RECRUITING
Conditions: Fibromyalgia
Interventions: OTHER: chiropractic manipulation|OTHER: sham manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improving Employment and Reducing Recidivism Among Prison Offenders Via Virtual Interview Training Tool (MICHR)
Status: COMPLETED
Conditions: Criminal Behavior
Interventions: BEHAVIORAL: Virtual Reality Job Interview Training|BEHAVIORAL: Services as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bryostatin 1 Plus Paclitaxel and Cisplatin in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: bryostatin 1|DRUG: cisplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Quetiapine vs Haloperidol Decanoate for the Long Term Treatment of Schizophrenia and Schizoaffective Disorder
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: quetiapine|DRUG: haloperidol decanoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Repeated Voluntary Drug Intoxication (IMVr): Characterization of a New Addictive Behavior by Clinical Phenotyping and Functional Imaging
Status: TERMINATED
Conditions: Volunteers Repeated Drug Poisoning|Alcoholic|Volunteers
Interventions: OTHER: MRI and biological assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Auto Bilevel Adherence Following a Poor Initial Encounter With Continuous Positive Airway Pressure (CPAP)
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: CPAP|DEVICE: Auto BiLevel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC