pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Gender-Relevant Tobacco Cessation Among Women in Brazil
Status: COMPLETED
Conditions: Tobacco Use Cessation
Interventions: BEHAVIORAL: Control|BEHAVIORAL: 12-home visits by the Community Health Worker + referring to an appointment for the participant to attend the tobacco cessation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Implementation of a Diabetes Management Protocol as Compared to Conventional Management in a Heart Hospital's Non-Intensive Care Unit: Randomized Clinical
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: BEHAVIORAL: Intensive education of the doctor/nursing team on the protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Determine the Effects of Food on the Pharmacokinetic Profile of PBT2
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Fed Cohort PBT2|DRUG: Fasted Cohort PBT2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Propolis Nanoparticles on Postoperative Pain and Bacterial Reduction in Mandibular Premolars
Status: UNKNOWN
Conditions: Necrotic Pulp
Interventions: DIETARY_SUPPLEMENT: Propolis nanoparticles extract solution|DRUG: sodium hypochlorite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of 3 Doses of NeoFuse Combined With MasterGraft Granules in Subjects Requiring Posterolateral Lumbar Fusion (PLF)
Status: COMPLETED
Conditions: Degenerative Disc Disease|Spondylolisthesis|Spinal Stenosis
Interventions: BIOLOGICAL: NeoFuse|PROCEDURE: posterolateral spinal fusion with instrumentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph3 Safety/Efficacy Study of Rolapitant for the Prevention of CINV in Subjects Receiving Highly Emetogenic Chemotherapy
Status: COMPLETED
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Rolapitant|DRUG: Granisetron|DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Paclitaxel-Eluting Balloon Angioplasty and Coroflex™-Stents in the Treatment of Bifurcated Coronary Lesions
Status: COMPLETED
Conditions: Ischemia|Stenosis
Interventions: DEVICE: drug eluting balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observer-Blinded Dose Escalating, Single Dose to Study Safety and Antimicrobial Efficacy of Gel vs. Placebo
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DRUG: J. lividum
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Cost-Effectiveness of Behavioral Counseling for Exercise in Men and Women Following Acute Myocardial Infarction (AMI) and Percutaneous Coronary Intervention (PCI)
Status: COMPLETED
Conditions: Coronary Arteriosclerosis|Myocardial Infarction
Interventions: BEHAVIORAL: Telephone-based physical activity counseling program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Effects of PEEP on Intracranial and Intraocular Pressure in Robot-assisted Laparoscopic Radical Prostatectomy
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: PROCEDURE: PEEP group|PROCEDURE: ZEEP group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TBTC Study 23C: Pharmacokinetics of Intermittent Rifabutin and Isoniazid With Daily Efavirenz
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: Rifabutin|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of QL1706 Plus Lenvatinib in Subjects With Advanced Renal Cell Carcinoma(RCC)
Status: UNKNOWN
Conditions: Advanced Renal Cell Carcinoma
Interventions: DRUG: QL1706 Plus Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: App-Based Mindfulness Meditation for People of Color Who Experience Race-Related Stress
Status: COMPLETED
Conditions: Stress, Psychological|Anxiety|Depression|Rumination|Emotional Regulation|Mindfulness|Self-Compassion|Emotional Distress
Interventions: BEHAVIORAL: Mindfulness meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact Of Sensory Re-Education Paradigm On Sensation And Quality Of Life In Patients Post-Covid 19 Polyneuropathy
Status: COMPLETED
Conditions: Post-COVID-19 Syndrome
Interventions: OTHER: sensory re-education training|OTHER: traditional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Sulfate Solution (SUPREP) Versus Polyethylene Glycol (PEG) Plus Ascorbic Acid
Status: COMPLETED
Conditions: Cathartic Colon
Interventions: DRUG: Oral sulfate solution (OSS)|DRUG: 2-L PEG/Asc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Validation of the Short-term Antimicrobial Action of Transplanted Bacteria
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: Autologous Microbiome Transplant|OTHER: Placebo Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Medication on Functional Connectivity
Status: COMPLETED
Conditions: Prescription Drug Abuse (Not Dependent)
Interventions: DRUG: Oxycodone Medication First|DRUG: Placebo First
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intervention for Smoking Cessation in Pre-Surgical Patients.
Status: RECRUITING
Conditions: Smoking|Smoking Cessation|Surgical Procedure, Unspecified
Interventions: BEHAVIORAL: Intensive intervention for smoking cessation|BEHAVIORAL: Brief intervention for smoking cessation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Fecal Microbiota Transplantation
Status: RECRUITING
Conditions: Crohn Disease|Ulcerative Colitis|Celiac Disease|Irritable Bowel Syndrome|Functional Dysphonia|Constipation|Clostridium Difficile Infection|Diabetes Mellitus|Obesity|Multidrug -Resistant Infection|Hepatic Encephalopathy|Multiple Sclerosis|Pseudo-Obstruction|Carbapenem-Resistant Enterobacteriaceae Infection|Vancomycin Resistant Enterococci Infection|Multiple Organ Dysfunction Syndrome|Dysbiotic Bowel Syndrome|MRSA Enteritis|Pseudomembranous Enterocolitis|Alopecia|Autism|Graft-versus-host Disease|Idiopathic Thrombocytopenic Purpura|Atopy or Allergy|Liver Disease|Alcohol Dependence|Psoriatic Arthropathy
Interventions: PROCEDURE: Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Operative Versus Non-operative Management of Subacromial Impingement
Status: ACTIVE_NOT_RECRUITING
Conditions: Subacromial Impingement Syndrome
Interventions: PROCEDURE: Acromioplasty|PROCEDURE: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of First MTPJ Arthrodesis as a Treatment in Hallux Rigidus
Status: ACTIVE_NOT_RECRUITING
Conditions: Hallux Rigidus
Interventions: PROCEDURE: Arthrodesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N-Acetylcysteine Augmentation in Treatment-Refractory Obsessive-Compulsive Disorder
Status: TERMINATED
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: N-Acetylcysteine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DRCR.Net Aflibercept vs. Bevacizumab + Deferred Aflibercept for the Treatment of CI-DME
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: intravitreous aflibercept|DRUG: Bevacizumab + Deferred Aflibercept Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-lesion Administration of Dexamethasone to Prevent the Development of Neuritis After Radiofrequency Ablation
Status: TERMINATED
Conditions: Neuritis|Radiofrequency Ablation
Interventions: DRUG: Dexamethasone 4 mg/ml|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Utility of 2- Octyl Cyanoacrylate (2-OCA)
Status: ENROLLING_BY_INVITATION
Conditions: Ascites|Fluid Loss
Interventions: OTHER: Dermabond
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Brentuximab Vedotin in CD30 Positive Epstein Barr Virus (EBV) Positive DLBCL of Elderly
Status: WITHDRAWN
Conditions: Lymphoma
Interventions: DRUG: brentuximab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concentrated Bone Marrow Aspirate in Revision ACL Reconstruction
Status: NOT_YET_RECRUITING
Conditions: Anterior Cruciate Ligament Injuries|Post-Traumatic Osteoarthritis of Knee|Bone Marrow Aspirate Concentrate|ACL Injury
Interventions: BIOLOGICAL: Concentrated Bone Marrow Aspirate Injection|PROCEDURE: Sham Incision|PROCEDURE: Revision Anterior Cruciate Ligament Reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Geranylgeraniol (GG) Sourced From Annatto on Sexual Health
Status: COMPLETED
Conditions: Sexual Health|Libido
Interventions: DIETARY_SUPPLEMENT: Placebo Supplementation|DIETARY_SUPPLEMENT: GG sourced from Annatto
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of IBI343 in Subjects With Advanced Gastric/Gastroesophageal Junction Adenocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Advanced Gastric/Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: IBI343 combined with IBI308
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Oral Carbohydrate Consumption Prior to Cesarean Section
Status: COMPLETED
Conditions: Dehydration
Interventions: DIETARY_SUPPLEMENT: Oral Carbohydrate Beverage|DIETARY_SUPPLEMENT: Rehydration beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Comparison of the Efficacy of Amisulpride and Placebo in the Prevention of PONV in Patients at Moderate-to-high Risk of PONV.
Status: NOT_YET_RECRUITING
Conditions: PONV
Interventions: DRUG: Amisulpride|DRUG: Amisulpride Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Botulinum A Toxin in Patients With Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson's Disease|Multiple System Atrophy|Detrusor Overactivity
Interventions: DRUG: Intravesical injection of Botulinum A toxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Nano-silver Fluoride and Silver Diamine Fluoride for Arresting Early Childhood Caries
Status: COMPLETED
Conditions: Early Childhood Caries
Interventions: DRUG: Nanosilver|DRUG: Silver diamine fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: VELCADE in Subjects With Relapsed or Refractory Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: VELCADE TM (bortezomib) for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Using a Clinical Support Tool in Managing Adolescents With Non-Traumatic Knee Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Pain Chronic
Interventions: OTHER: Using the MAP-Knee Tool|OTHER: Usual practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer
Status: RECRUITING
Conditions: Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma|Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7|Stage III Laryngeal Squamous Cell Carcinoma AJCC v6 and v7|Stage III Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7|Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7|Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7|Stage IV Laryngeal Squamous Cell Carcinoma AJCC v7|Stage IV Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7|Stage IV Oropharyngeal Squamous Cell Carcinoma AJCC v7
Interventions: DRUG: Atezolizumab|PROCEDURE: Biospecimen Collection|BIOLOGICAL: Cetuximab|DRUG: Cisplatin|PROCEDURE: Computed Tomography|DRUG: Docetaxel|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Magnetic Resonance Imaging|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ANI-guided Intraoperative Analgesia in Low-pressure Anesthesia
Status: RECRUITING
Conditions: Analgesia|Functional Endoscopic Sinus Surgery|Heart Rate Variability|Opioid Consumption
Interventions: DEVICE: analgesia nociception index
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Fluvoxamine and Smoking on Pharmacokinetics ( the Movement of Drugs Within the Body) of AZD4635 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer/DDI Study
Interventions: DRUG: AZD4635|DRUG: Fluvoxamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label, Randomised, Repeat Dose Study to Assess the Pharmacokinetic Performance of Five Ezogabine/Retigabine Modified Release (MR) Formulations at Steady State Compared to the Immediate Release (IR) Formulation.
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Investigational Medicinal Product (MR1)|DRUG: Investigational Medicinal Product (MR2)|DRUG: Investigational Medicinal Product (MR3)|DRUG: Investigational Medicinal Product (MR4)|DRUG: Investigational Medicinal Product (MR5)|DRUG: Investigational Medicinal Product (IR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerability of Cannabis in Patients Receiving Concurrent Chemoradiation for Glioblastoma
Status: TERMINATED
Conditions: Glioblastoma
Interventions: DRUG: Cannabis|DRUG: Temozolomide|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Activity of Robatumumab (SCH 717454, MK-7454) in Participants With Relapsed or Recurrent Colorectal Cancer (P04721, MK-7454-003)
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: Robatumumab|DRUG: Irinotecan|BIOLOGICAL: Cetuximab|DRUG: Capecitabine|DRUG: FOLFOX|DRUG: CAPEOX/XELOX|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Treatment of Pediatric MDD to Increase Remission and Prevent Relapse
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Fluoxetine|BEHAVIORAL: Relapse prevention cognitive behavioral therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Alternative Dose Interval Study in Participants With Hidradenitis Suppurativa Receiving Brodalumab
Status: WITHDRAWN
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Brodalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Simultaneous Resection of Colorectal Cancer With Synchronous Liver Metastases
Status: COMPLETED
Conditions: ColoRectal Cancer|Liver Metastases|Liver Metastasis Colon Cancer|Surgery|Complication
Interventions: PROCEDURE: Simultaneous Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SonoVue®-Enhanced Ultrasound (US) Versus Unenhanced US for Focal Liver Lesion Characterization
Status: COMPLETED
Conditions: Liver Neoplasms
Interventions: DRUG: SonoVue®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Immunogenicity of the Inactivated Rabies Vaccine RABIVAX-S Administered Intramuscularly and Intradermally
Status: COMPLETED
Conditions: Rabies
Interventions: BIOLOGICAL: RABIVAX-S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Aortic Valve Sparing Root Replacement Versus Bentall
Status: RECRUITING
Conditions: Aortic Root Aneurysm|Aortic Root Dissection
Interventions: PROCEDURE: Aortic valve sparing operation|PROCEDURE: Bentall operation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Donor Stem Cell Transplant, Pentostatin, and Total-Body Irradiation in Treating Patients With Hematological Cancer
Status: WITHDRAWN
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Myelodysplastic Syndromes|Nonmalignant Neoplasm
Interventions: DRUG: cyclosporine|DRUG: mycophenolate mofetil|DRUG: pentostatin|GENETIC: cytogenetic analysis|GENETIC: fluorescence in situ hybridization|GENETIC: protein analysis|OTHER: flow cytometry|OTHER: immunoenzyme technique|OTHER: laboratory biomarker analysis|OTHER: reduced-intensity transplant conditioning procedure|PROCEDURE: nonmyeloablative allogeneic hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation (PBSC)|RADIATION: total-body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Erlotinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer
Status: COMPLETED
Conditions: Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Nasopharynx|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Salivary Gland Squamous Cell Carcinoma|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Larynx|Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IV Squamous Cell Carcinoma of the Oropharynx|Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity
Interventions: BIOLOGICAL: bevacizumab|DRUG: erlotinib hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Link Between the Characteristics of Oral Physiology and the Formation of the Food Bolus During the Consumption of Dairy Products in Elderly People
Status: UNKNOWN
Conditions: Old Person
Interventions: OTHER: Two samples of saliva|OTHER: Chewing behaviour|OTHER: Study of the food bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Web-Based Gentle Body Stretching to Alleviate Loneliness and Improve Mental Fitness During COVID-19 Isolation Period
Status: COMPLETED
Conditions: Mental Health Issue
Interventions: BEHAVIORAL: Mindfulness intervention|BEHAVIORAL: Non-Mindfulness intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: VATS Decortication Versus IR Guided Chest Tube Insertion With Fibrinolytics for the Management of Empyema
Status: RECRUITING
Conditions: Empyema, Pleural
Interventions: OTHER: Video assisted thorascopic decortication|OTHER: Interventional radiology guided chest tube insertion with MIST2 trial fibrinolytics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HAIC Plus Lenvatinib and Toripalimab for Advanced HCC
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Hepatic arterial infusion chemotherapy|DRUG: Lenvatinib|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CART-BCMA/CS1 in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: WITHDRAWN
Conditions: Recurrent Multiple Myeloma|Refractory Multiple Myeloma
Interventions: PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|DRUG: Cyclophosphamide|PROCEDURE: Echocardiography|DRUG: Fludarabine|OTHER: Fludeoxyglucose F-18|OTHER: Immunotherapy|PROCEDURE: Leukapheresis|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nab-PTX Plus S-1 and Sintilimab as Adjuvant Therapy in Patients With Stage IIIC Gastric Cancer
Status: UNKNOWN
Conditions: Stage IIIC Gastric Cancer
Interventions: DRUG: Nab-PTX, Sintilimab, S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examination of Clinical and Laboratory Abnormalities in Patients With Defective DNA Repair: Xeroderma Pigmentosum, Cockayne Syndrome, or Trichothiodystrophy
Status: COMPLETED
Conditions: Cockayne Syndrome|Skin Neoplasms|Xeroderma Pigmentosum|Trichothiodystrophy Syndromes|Genodermatosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pyridoxine in Preventing Hand-Foot Syndrome Caused by Capecitabine in Patients With Cancer
Status: TERMINATED
Conditions: Dermatologic Complications|Palmar-plantar Erythrodysesthesia|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DIETARY_SUPPLEMENT: pyridoxine hydrochloride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating the Effect of Person-centred Care for Patients Admitted for Inpatient Care at an Internal Medicine Unit
Status: COMPLETED
Conditions: Endocrine System Diseases|Gastrointestinal Diseases
Interventions: OTHER: Person-centred inpatient care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: CardioRenal Effects of SGLT2 Inhibition in Kidney Transplant Recipients
Status: RECRUITING
Conditions: Kidney Transplant; Complications|Diabetes Mellitus, Type 2
Interventions: DRUG: Empagliflozin10Mg Tab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Can rTMS Enhance Somatosensory Recovery After Stroke?
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: repetitive transcranial magnetic stimulation (rTMS)|OTHER: peripheral sensory stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Automated Navigation to Improve Outpatient Colonoscopy Adherence
Status: COMPLETED
Conditions: Adherence, Patient|Colonoscopy|Text Messaging
Interventions: BEHAVIORAL: Text Message-based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Risk Factors of Complications Regarding Patients Undergoing Brain Tumour Neuro-surgery (Cranioscore).
Status: COMPLETED
Conditions: Neuro-surgery|Brain Tumor|Post-operative Complications|Neuro-ICU Stay
Interventions: OTHER: Collecting pre-operative, per-operative data, neuro-radiological data and post-operative neuro-surgery complications
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: AUTOLOGOUS FIBRIN GLUE VERSES 4-0 SILK SUTURES IN PERIODONTAL FLAP CLOSURE
Status: UNKNOWN
Conditions: Periodontitis
Interventions: PROCEDURE: Periodontal Flap Surgery|OTHER: Autologous fibrin glue|OTHER: 4-0 silk suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Group A, C, Y and W135 Meningococcal Polysaccharide Vaccine
Status: COMPLETED
Conditions: Meningitis
Interventions: BIOLOGICAL: Group T|BIOLOGICAL: Group C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: QoR40 Between Intercostal Block and Intercostal Block and Serratus Plane Catheter During VATS
Status: RECRUITING
Conditions: Video Assisted Thoracic Surgery (VATS)|Pain Management
Interventions: PROCEDURE: Serratus Plane Block (Local Anesthetic) and Intercostal Block (Local Anesthetic)|PROCEDURE: Serratus Plane Block (Placebo) and Intercostal Block (Local Anesthestic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DC Vaccines Targeting HPV16/18 E6/E7 Protein to Regress CINI/CIN2
Status: UNKNOWN
Conditions: Cervical Intraepithelial Neoplasia
Interventions: BIOLOGICAL: Vaccinated group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Adult Antiretroviral Treatment and Resistance Study (Tshepo)
Status: COMPLETED
Conditions: AIDS|HIV Infection
Interventions: DRUG: (A) zidovudine, lamivudine and nevirapine|DRUG: (B) zidovudine, lamivudine and efavirenz|DRUG: (C) zidovudine, didanosine, and nevirapine|DRUG: (D) zidovudine, didanosine, and efavirenz|DRUG: (E) stavudine, lamivudine, and nevirapine|DRUG: (F) stavudine, lamivudine and efavirenz|PROCEDURE: Adherence Strategy Standard of Care (SOC)|PROCEDURE: Adherence Strategy Community-Based DOT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Family-Centered Physiotherapy in Dyskinetic Cerebral Palsy
Status: NOT_YET_RECRUITING
Conditions: Cerebral Palsy, Dyskinetic
Interventions: OTHER: Family-Centered Goal-Oriented Physiotherapy and Rehabilitation Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Immunotherapy in EGFR-mutant Localized NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer|EGFR Activating Mutation
Interventions: BIOLOGICAL: Sintilimab|DRUG: Carboplatin|DRUG: Nab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Denosumab on Bone and Vascular Metabolism in Osteoporotic Chronic Kidney Disease
Status: TERMINATED
Conditions: Female With Osteoporosis and Chronic Kidney Disease
Interventions: DRUG: Denosumab|DRUG: NaCl (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Olanzapine Impact on First-line Immunotherapy for Advanced EGFR-negative NSCLC
Status: NOT_YET_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Olanzapine|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate a Phase I/II Clinical Study of XNW5004 Tablets in Patients With Relapsed/Refractory Advanced Tumors
Status: RECRUITING
Conditions: Advanced Tumor|Lymphoma
Interventions: DRUG: XNW5004 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maximal Fat Oxidation and Fuel Use During Exercise
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: investigate the nutritional determinants of MFO in moderate to well-train individuals|OTHER: Investigate the physiological determinants of MFO in moderate to well-train individuals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Compare the Safety, Tolerability, and Efficacy of Influenza Virus Vaccine, (CAIV-T) With Inactivated, Influenza Vaccine, Trivalent, Types A & B, in Adults Aged 60 Years and Older Against Culture-confirmed Influenza
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Cold-adapted influenza vaccine trivalent (CAIV-T)|BIOLOGICAL: Trivalent Inactivated Vaccine (TIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Moringa Oleifera Capsule in Increasing Breast Milk Volume in Early Postpartum Patients
Status: COMPLETED
Conditions: Postpartum Women
Interventions: DRUG: Moringa oleifera leaf|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Cellular Adoptive Immunotherapy Using Genetically Modified T-Lymphocytes in Treating Patients With Recurrent or Refractory High-Grade Malignant Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: therapeutic autologous lymphocytes|GENETIC: gene expression analysis|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Uncovering the Cognitive and Neural Mechanisms Underlying Cognitive Time
Status: NOT_YET_RECRUITING
Conditions: Healthy Aging
Interventions: RADIATION: FDOPA injection before PET imaging|BEHAVIORAL: Time perception tasks|DEVICE: fMRI imaging|DEVICE: EEG imaging|BEHAVIORAL: 3 year follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vitamin D and Prostate Cancer: A Clinical Study Enrolling Subjects Undergoing Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: cholecalciferol|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Monopolar Electrosurgery Versus Ultrasound Scissors in Thoracoscopic Ventral Spondylodesis
Status: UNKNOWN
Conditions: Fractures of Vertebral Bodies
Interventions: DEVICE: ultrasound scissors - Harmonic ACE|DEVICE: electroscalpel (Erbe Vio 300; Aesculap AG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long-term Safety and Tolerability of Iptacopan in Patients With Paroxysmal Nocturnal Hemoglobinuria
Status: RECRUITING
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: Iptacopan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Response to the Anti-cancer Drug, Triapine, in Uterine Cancers Using Markers From the Tissue at the Time of Hysterectomy
Status: RECRUITING
Conditions: Endometrial Serous Adenocarcinoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Resection|DRUG: Triapine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Game Activity and Stress Ball on Anxiety and Vital Signs
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Arthroplasty Complications
Interventions: BEHAVIORAL: Game activity|DEVICE: Stres Ball
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Depression and Quality of Life in Chronic Heart Failure Patients and the Caregivers
Status: COMPLETED
Conditions: Chronic Heart Failure (CHF)|Anxiety and Depression|Quality of Life (QOL)|Exercise
Interventions: OTHER: Home-based exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Genetic Screening and Assisted Oocyte Activation in Couples With Diminished/Aberrant Embryonic Development.
Status: COMPLETED
Conditions: Embryo|Embryo Disorder|Genetic Disease
Interventions: PROCEDURE: AOA|DIAGNOSTIC_TEST: Genetic screening|DIAGNOSTIC_TEST: Calcium pattern analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interdental Plaque Reduction and Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: BEHAVIORAL: Interdental Oral Hygiene Instruction (Int-OHI)|PROCEDURE: One session of professional supragingival scaling and polishing|PROCEDURE: Oral Hygiene Instruction (OHI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of CAStem for Severe COVID-19 Associated With/Without ARDS
Status: UNKNOWN
Conditions: COVID-19|Acute Respiratory Distress Syndrome|Virus; Pneumonia|Acute Lung Injury
Interventions: BIOLOGICAL: CAStem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Static Magnetic Therapy for Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: Strong Magnetic Wristband|DEVICE: Weaker Magnetic Wristband
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy Study to Evaluate Alfuzosin to Treat Men With Erectile Dysfunction and Mild Lower Urinary Tract Symptoms
Status: COMPLETED
Conditions: Erectile Dysfunction|Lower Urinary Tract Symptoms
Interventions: DRUG: Placebo|DRUG: Alfuzosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Ramelteon on Sleep and Delirium in Patients Who Undergo Pulmonary Thromboendarterectomy (PTE) Surgery
Status: UNKNOWN
Conditions: Delirium|Sleep Deprivation
Interventions: DRUG: Ramelteon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Wearable Sensor-based Interactive Cognitive-motor Training in Older Adults.
Status: COMPLETED
Conditions: Cognitive Decline, Mild|Cognition Disorders in Old Age|Subjective Memory Decline
Interventions: BEHAVIORAL: cognitive-motor training|BEHAVIORAL: cognition training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gaze and Gait Training With rTMS
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)|BEHAVIORAL: Gait training|BEHAVIORAL: Gaze training|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: FMP2.1/AS02A: Rabies Vaccine Malaria-Experienced Adults in Bandiagara, Mali
Status: COMPLETED
Conditions: Malaria|Plasmodium Falciparum Malaria
Interventions: BIOLOGICAL: FMP2.1/AS02A|BIOLOGICAL: Rabies vaccine (RabAvert)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Medical Safety Follow-up Study for Patients Who Received More Than 28 Days of Total Exposure to BGG492
Status: COMPLETED
Conditions: Adrenocortical Adenoma|Endometrial Stromal Sarcomas
Interventions: PROCEDURE: MRI, CT or ultrasound was permitted if MRI was contraindicated|PROCEDURE: Dexamethasone Supression Test|PROCEDURE: Sonogram|PROCEDURE: Biopsy|DRUG: BGG492
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: RandOmised Controlled Trial of STAR Mapping™ Guided Ablation for AF.
Status: WITHDRAWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Pulmonary vein isolation plus ablation guided by novel STAR mapping™|PROCEDURE: Pulmonary vein isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clomifene Citrate as First Line Treatment in in Vitro Fertilization Cycles for Patients With Lower Ovarian Reserve
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Clomifene Citrate|DRUG: GnRH analog and recombinant human FSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Mediational Intervention for Sensitizing Caregivers for Teachers and Self-Administered Versions
Status: RECRUITING
Conditions: Randomized Controlled Trial
Interventions: BEHAVIORAL: Mediational Intervention for Sensitizing Caregivers, Teachers' version (MISC-T)|BEHAVIORAL: Mediational Intervention for Sensitizing Caregivers, Self-Administered version (MISC-SA)|OTHER: Mediational Intervention for Sensitizing Caregivers - Readings version (MISC-R): Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Status and ASD Severity of Autistic Spectrum Disorder Children in Addis Ababa, Ethiopia; Case Control Study
Status: COMPLETED
Conditions: Autistic Spectrum Disorder
Interventions: OTHER: Nutritional status|BEHAVIORAL: Eating behavior|OTHER: Urine iodine concentration|OTHER: Nutrient intake|OTHER: Dietary assessment|OTHER: Childhood autism rating scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative Disorders
Status: COMPLETED
Conditions: Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative|Chronic Myelomonocytic Leukemia|de Novo Myelodysplastic Syndrome|Essential Thrombocythemia|Myeloproliferative Neoplasm|Paroxysmal Nocturnal Hemoglobinuria|Polycythemia Vera|Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase|Primary Myelofibrosis|Refractory Anemia|Refractory Anemia With Excess Blasts|Refractory Anemia With Ring Sideroblasts|Refractory Cytopenia With Multilineage Dysplasia|Refractory Cytopenia With Multilineage Dysplasia and Ring Sideroblasts
Interventions: DRUG: Cyclosporine|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|DRUG: Mycophenolate Mofetil|PROCEDURE: Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation|PROCEDURE: Peripheral Blood Stem Cell Transplantation|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Aloe Vera Versus Fluoride Toothpaste in Changing High to Low Salivary Bacterial Count
Status: UNKNOWN
Conditions: Caries, Dental
Interventions: DRUG: aloe vera toothpaste|DRUG: fluoride toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Low Calorie Diet With Rice Bran Oil on Cardiovascular Risk Factors in Hyperlipidemic Patients
Status: UNKNOWN
Conditions: Hyperlipidemias
Interventions: DIETARY_SUPPLEMENT: rice bran oil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Scoreflex TRIO - Scoring PTCA Catheter
Status: COMPLETED
Conditions: Coronary Arteriosclerosis
Interventions: DEVICE: OrbusNeich Scoreflex TRIO|DEVICE: OrbusNeich Scoreflex NC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation of the Arrhythmia Mechanism and Substrate to Ablate Persistent Atrial Fibrillation Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: Catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Biphasic Bone Graft Material With Autologous Platelet-rich Fibrin on Bone Regeneration in a Maxillary Cyst
Status: UNKNOWN
Conditions: Odontogenic Maxillary Cysts
Interventions: PROCEDURE: Biphasic Bone Graft Material (BGM) in Combination With Autologous Platelet-rich Fibrin (PRF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Trial of AMI MultiStem® Therapy in Subjects With Non-ST Elevation Acute Myocardial Infarction
Status: TERMINATED
Conditions: Heart Attack|NSTEMI
Interventions: BIOLOGICAL: AMI MultiStem cells|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Predictors of Cancer in Patients at High Risk of Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer
Interventions: GENETIC: comparative genomic hybridization|GENETIC: gene expression microarray analysis|GENETIC: proteomic profiling analysis|OTHER: biologic sample preservation procedure|PROCEDURE: nasal brushing|PROCEDURE: Blood draw|PROCEDURE: Urine collection|PROCEDURE: sputum sample|PROCEDURE: fluorescence bronchoscopy with airway biopsy|PROCEDURE: fine needle aspiration of the lung|PROCEDURE: thoracentesis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Ankle Support on Muscle Activation and Function
Status: COMPLETED
Conditions: Ankle Sprain
Interventions: OTHER: Fibular Taping|OTHER: Sham Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Chemotherapeutic Agent Toxicity|Cognitive/Functional Effects|Fatigue|Long-term Effects Secondary to Cancer Therapy in Adults|Neurotoxicity|Psychosocial Effects of Cancer and Its Treatment
Interventions: BIOLOGICAL: trastuzumab|DRUG: aromatase inhibition therapy|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: docetaxel|DRUG: doxorubicin hydrochloride|OTHER: metabolic assessment|OTHER: questionnaire administration|OTHER: study of socioeconomic and demographic variables|PROCEDURE: cognitive assessment|PROCEDURE: positron emission tomography|RADIATION: fludeoxyglucose F 18
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Therapy With Dalfampridine and Locomotor Training for Chronic, Motor Incomplete Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DRUG: Dalfampridine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT