pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pilot Study of the Effects of Resveratrol Supplement in Mild-to-moderate Alzheimer's Disease
Status: WITHDRAWN
Conditions: Alzheimer Disease
Interventions: DIETARY_SUPPLEMENT: Longevinex brand resveratrol supplement|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficiency of ESWT and Custom İnsoles Produced With Podometric Measurement in the Treatment of Painful Heel Spurs (ESWT: Extracorporeal Shock Wave Therapy)
Status: RECRUITING
Conditions: Heel Spur|Heel Spur Syndrome|Heel Pain Syndrome
Interventions: DEVICE: ESWT|DEVICE: customized insoles|COMBINATION_PRODUCT: combined ESWT and custtomized insoles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Statin Therapy In Cardiac Surgery
Status: COMPLETED
Conditions: Atrial Fibrillation|Myocardium; Injury
Interventions: DRUG: Rosuvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Efficacy and Pharmacokinetics of CBT-006 in Patients With Meibomian Gland Dysfunction
Status: COMPLETED
Conditions: Meibomian Gland Dysfunction
Interventions: DRUG: CBT-006
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Examine the Impact of Early Education on COPD Management
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: OTHER: Pulmonary Education (PE)|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Serum Presepsin as Early Predictor for Neonatal Early-onset Sepsis
Status: COMPLETED
Conditions: Neonatal Sepsis
Interventions: DIAGNOSTIC_TEST: Serum Presepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Non-invasive Left-sided Cervical Vagus Nerve Stimulation for Atrioventricular Reentrant Tachycardia
Status: RECRUITING
Conditions: Atrioventricular Reentrant Tachycardia
Interventions: DEVICE: Non-invasive vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) Versus Placebo in Peri- and Postmenopausal Women
Status: COMPLETED
Conditions: Depression|Depressive Disorder|Depressive Disorder, Major
Interventions: DRUG: Desvenlafaxine administered as a succinate salt in a sustained-release form (DVS SR)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Renal Failure in Children With Urinary Tract Infections
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: BEHAVIORAL: Written information for parents|BEHAVIORAL: Distance learning package for General Practitioners|BEHAVIORAL: Distance learning package for practice assistants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose:
Clinical trial: Study of Concurrent Pemetrexed, Cisplatin and Radiotherapy in Local Advanced Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Local Advanced Non-Small Cell Lung Cancer
Interventions: OTHER: Concurrent Pemetrexed, Cisplatin and Radiotherapy|OTHER: Concurrent Pemetrexed, Cisplatin and Radiotherapy|OTHER: Concurrent Pemetrexed, Cisplatin and Radiotherapy|OTHER: Concurrent Pemetrexed, Cisplatin and Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and Usage Compliance of the Silk'n Tightra Device
Status: COMPLETED
Conditions: Stress Urinary Incontinence|Sexual Dysfunction|Vulvovaginal Atrophy
Interventions: DEVICE: Tightra vaginal device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optical Imaging of Head and Neck Cancer
Status: TERMINATED
Conditions: Squamous Cell Carcinoma|Neoplasia|Head and Neck Cancer
Interventions: DEVICE: High Resolution Microendoscopy (HRME)|OTHER: Proflavine hemisulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Intravenous and Multiple Subcutaneous and Intravenous Doses of PF-06480605 in Healthy Subjects.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06480605|DRUG: Placebo|DRUG: PF-06480605|DRUG: Placebo|DRUG: PF-06480605|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Different Routes of Misoprostol Prior to First Trimester Surgical Abortion
Status: UNKNOWN
Conditions: Abortion, Induced
Interventions: DRUG: Misoprostol (cytotec)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Cyclosporine Microemulsion in Diabetic Adult Stable Liver Transplant Recipients
Status: COMPLETED
Conditions: Liver Transplant
Interventions: DRUG: Cyclosporine microemulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: One-day Life Skills Workshop for Veterans With TBI, Pain, and Psychopathology: Evaluating Efficacy and Mechanism of Change
Status: COMPLETED
Conditions: Traumatic Brain Injury|Chronic Pain|Post Traumatic Stress Disorder|Depression|Anxiety
Interventions: BEHAVIORAL: ACT on Life|BEHAVIORAL: Education, Resources, and Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Labor and Delivery Implant Insertion: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Postpartum Contraception|Family Planning
Interventions: DRUG: Etonogestrel-Immediate|DRUG: Etonogestrel-Delayed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Osteosarcoma With Resectable Pulmonary Metastasis: A Retrospective Study
Status: COMPLETED
Conditions: Osteosarcoma Metastatic|Pulmonary Disease|Resectable Sarcoma|Survival
Interventions: PROCEDURE: resection group|RADIATION: radiotherapy group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Trial Comparing the Impact of One Versus Two Courses of Antenatal Steroids (ACS) on Neonatal Outcome
Status: COMPLETED
Conditions: Preterm Delivery
Interventions: DRUG: Betamethasone or Dexamethasone (2nd course of ACS)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of HL-040XC in Essential Hypertension and Hyperlipidemia
Status: COMPLETED
Conditions: Essential Hypertension|Hyperlipidemia
Interventions: DRUG: Atorvastatin|DRUG: Losartan|DRUG: Placebo|DRUG: HL-040XC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Electrical Stimulation for the Treatment of Pain Following Total Knee Arthroplasty Using the SPRINT Beta System
Status: COMPLETED
Conditions: Total Knee Replacement|Total Knee Arthroplasty|Pain|Postoperative Pain|Orthopedic Disorder
Interventions: DEVICE: SPRINT Beta System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Efficacy of RENASYS TOUCH NPWT System in the Management of Acute, Sub-acute and Chronic Wounds
Status: COMPLETED
Conditions: Wound and Injuries|Surgical Wound Dehiscence
Interventions: DEVICE: RENASYS TOUCH Negative Pressure Wound Therapy System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRI-VENT FSGS: Preemptive Rituximab to Prevent Recurrent Focal Segmental Glomerulosclerosis Post-Transplant
Status: RECRUITING
Conditions: Focal Segmental Glomerulosclerosis
Interventions: DRUG: Rituximab|PROCEDURE: Plasmapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial of CSL's 2009 H1N1 Influenza Vaccine (CSL425) in a Healthy Pediatric Population in the USA
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: CSL's 2009 H1N1 Influenza Vaccine (CSL425)|BIOLOGICAL: CSL's 2009 H1N1 Influenza Vaccine (CSL425)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Low-Dose Total-Body Irradiation and Fludarabine Phosphate Followed by Unrelated Donor Stem Cell Transplant in Treating Patients With Fanconi Anemia
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia in Remission|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Childhood Acute Myeloid Leukemia in Remission|Childhood Myelodysplastic Syndromes|Fanconi Anemia|Previously Treated Myelodysplastic Syndromes
Interventions: DRUG: fludarabine phosphate|DRUG: cyclosporine|RADIATION: total-body irradiation|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation|DRUG: mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computer Program for Evaluation of the Symmetry Between the Primary Sulci of the Two Fetal Brain Hemispheres and Midsagittal Fetal Head Biometry Using 3-dimensional Ultrasound Planes.
Status: UNKNOWN
Conditions: Normal Fetal Brain Sulcation
Interventions: OTHER: computerized analysis of sonographic images
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I, Dose-Escalating Safety and Tolerance Study of sCD4-PE40 in HIV-Infected Persons
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Alvircept sudotox|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody Therapy Plus Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: monoclonal antibody A33|DRUG: carmustine|DRUG: fluorouracil|DRUG: streptozocin|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Carboplatin, Etoposide, Cyclophosphamide, and Autologous Bone Marrow Transplantation in Patients With Relapsed or Refractory Cancer
Status: COMPLETED
Conditions: Extragonadal Germ Cell Tumor|Ovarian Cancer|Testicular Germ Cell Tumor|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: etoposide|PROCEDURE: autologous bone marrow transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Heart Failure With Reduced Ejection Fraction - COngestion Discharge Evaluation
Status: RECRUITING
Conditions: Acute Heart Failure
Interventions: PROCEDURE: Clinical examination centered on congestion|PROCEDURE: Cardio-pulmonary, peritoneal, jugular and renal Doppler ultrasounds and liver elastography|PROCEDURE: Biological: Blood sample retrieved for biological assessment and biobanking|PROCEDURE: Telephone interview|BEHAVIORAL: Kansas City Cardiomyopathy Questionnaire (KCCQ)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ozonated Olive Oil and Low-Level Laser Therapy in TMD Treatment
Status: COMPLETED
Conditions: TMD
Interventions: DRUG: Ozonized Olive Oil Solutions|DEVICE: Low Level Laser LLL Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Initiation of CPAP for Newly Diagnosed OSA in Hospitalized Heart Failure Patients
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Heart Failure
Interventions: DEVICE: Continuous Positive Airway Pressure (CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Citalopram HBr 10 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Citalopram HBr eq. 10 mg tablets, single dose|DRUG: CELEXATM 10 mg tablets, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Sorafenib Tosylate, Bevacizumab, Irinotecan Hydrochloride, Leucovorin Calcium, and Fluorouracil in Treating Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Recurrent Colon Carcinoma|Recurrent Rectal Carcinoma|Stage IVA Colon Cancer|Stage IVA Rectal Cancer|Stage IVB Colon Cancer|Stage IVB Rectal Cancer
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Fluorouracil|DRUG: Irinotecan Hydrochloride|DRUG: Leucovorin Calcium|DRUG: Sorafenib Tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplant (FMT) in Melanoma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: DRUG: Fecal Microbiota Transplant with Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-line Icotinib With Concurrent Radiotherapy for NSCLC With EGFR Mutation
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: icotinib|DRUG: Chemotherapy|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Proposal for Web Based Intervention to Promote the Safe Usage of Dating Applications in Young Adults
Status: COMPLETED
Conditions: Sex, Unsafe|Adolescent Behavior|Behavior, Sex
Interventions: BEHAVIORAL: Intervention - Dating application topic|BEHAVIORAL: Control - Health and exercise topic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Oral Posaconazole in High Risk Patients With Gastrointestinal Dysfunction (Study P05115)
Status: COMPLETED
Conditions: Fungal Infection|Acute Myelogenous Leukemia|Neutropenia
Interventions: DRUG: Posaconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transversus Abdominis Plane Catheter: a Study of Method
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Placing bilateral TAP-catheters preoperatively|DRUG: Bupivacain 2.5 mg/ml with epinephrine bolus in TAP-catheters
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Alternate Dosing - Initiation of Every 2 Week Epoetin Alfa (PROCRIT) in the Treatment of Anemia.
Status: COMPLETED
Conditions: Anemia|Kidney Diseases
Interventions: DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BEhavioral EConomics for Oral Health iNnovation Pilot Trial
Status: COMPLETED
Conditions: Toothbrushing|Dental Plaque|Parent-Child Relations|Oral Hygiene|Dental Caries
Interventions: BEHAVIORAL: Fixed Incentive|BEHAVIORAL: Drawing Incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dynamic Effects of Online HDF on Cardiac Function and Myocardial Perfusion Utilising Cardiac MRI (CAMRID)
Status: COMPLETED
Conditions: Other Postprocedural Cardiac Functional Disturbances|Myocardial Perfusion
Interventions: OTHER: online Hemodiafiltration|OTHER: Hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: ACEi/ARB Alone Versus ACEi/ARB Plus Steroids in the Treatment of Primary IgA Nephropathy, a RCT
Status: UNKNOWN
Conditions: Glomerulonephritis, IGA
Interventions: DRUG: prednisone + Inhibace/Cozaar|DRUG: Inhibace/Cozaar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Confirmation Efficacy Study (V260-007)
Status: COMPLETED
Conditions: Rotavirus Infections
Interventions: BIOLOGICAL: RotaTeq™, rotavirus vaccine, live, oral, pentavalent|BIOLOGICAL: Comparator: Placebo matching RotaTeq™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Rozanolixizumab Administered Subcutaneously Via Manual Push Versus Syringe Driver to Healthy Participants
Status: COMPLETED
Conditions: Healthy Study Participants
Interventions: DRUG: rozanolixizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Antibody Persistence and Response to Re-vaccination With Either Menactra® or Menomune® 3 Years After Initial Vaccination
Status: COMPLETED
Conditions: Meningitis|Meningococcal Meningitis|Meningococcal Infections
Interventions: BIOLOGICAL: Menomune®: A, C, Y, W 135 Meningococcal Polysaccharide|BIOLOGICAL: Menactra®: Meningococcal (A, C, Y and W 135) Polysaccharide Diphtheria Toxoid Conjugate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics/Safety of Miltefosine Allometric Dose for the Treatment of Visceral Leishmaniasis in Children in Eastern Africa
Status: COMPLETED
Conditions: Visceral Leishmaniasis
Interventions: DRUG: Miltefosine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identifying Therapeutic Factors in an 8-Week (30 Hour) Mindfulness-Based Stress Reduction (MBSR) Program
Status: COMPLETED
Conditions: Cancer|Diabetes|Hypertension
Interventions: BEHAVIORAL: Teaching Mindfulness-based Stress Reduction strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Omega-3 Polyunsaturated Fatty Acids in Youth With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|ADHD
Interventions: DIETARY_SUPPLEMENT: n-3 Polyunsaturated fatty acid|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Efficacy and Safety of Combination Therapy of Motireb 5/100 mg in Functional Dyspepsia Patients.
Status: UNKNOWN
Conditions: Functional Dyspepsia
Interventions: DRUG: Motireb 5/100 mg|DRUG: Mosapride citrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microbial Profiling in Pockets Related to Chronic Periodontitis Patients Using 16s RNA Metagenomics Sequencing
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: GENETIC: 16s RNA Metagenomics sequencing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Placebo Development and Validation for Healing Water
Status: COMPLETED
Conditions: Balneology
Interventions: OTHER: Colored healing water|OTHER: Placebo treatment (colored tap water)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of a Low Dose, Oral, Liquid Iron Supplement on Restoring Inadequate Blood Iron to Normal Levels
Status: COMPLETED
Conditions: Iron Deficiency (Without Anemia)
Interventions: DIETARY_SUPPLEMENT: Liquid Placebo Supplementation|DIETARY_SUPPLEMENT: Liquid Iron Supplement (Blood Builder ®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Loading Dose or Standard Dose of Intravenous Ibandronate in Treating Patients With Lung Cancer and Skeletal Metastasis
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: Ibandronate (Bondronat)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Calcium Supplement Attenuate Bone Loss Among HIV- Infected Patients Receiving Tenofovir Disoproxil Fumarate, Lamivudine or Emtricitabine and Efavirenz
Status: UNKNOWN
Conditions: Bone Density
Interventions: DRUG: TDF/3TC or FTC/EFV plus Calcium and vitamin D supplement|OTHER: TDF/3TC or FTC/EFV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hypofractionated Whole-breast Irradiation With Simultaneously Integrated Boost For Early-Stage Breast Cancer After Breast-conserving Surgery
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: RADIATION: hypofractionated whole breast irradiation with simultaneously integrated boost
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbon Dioxide-laser Versus Harmonic Scalpel in the Treatment of Pelvic Pain Due to Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DEVICE: Laser|DEVICE: Harmonic scalpel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DISCO Application for the Improvement of Financial Outcomes in Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Plasma Cell Myeloma
Interventions: BEHAVIORAL: The DISCO App|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Mask Ventilation Before and After Neuromuscular Blockade
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Rocuronium|DRUG: Vecuronium Bromide|DRUG: Succinylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-PD-L1 in Stage IIIA(N2) Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: NSCLC Non-small Cell Lung Cancer
Interventions: DRUG: MEDI4736 (anti-PD-L1)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous (IV) Decitabine and Oral Bexarotene for Acute Myelogenous Leukemia (AML)
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Decitabine|DRUG: Bexarotene
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Taxotere, Cisplatin, 5-Fluorouracil, and Leucovorin for Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Squamous Cell Carcinoma|Carcinoma of Head and/or Neck
Interventions: DRUG: Taxotere|DRUG: Cisplatin|DRUG: 5-Fluorouracil|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Bypass Trial for Completion Control
Status: NOT_YET_RECRUITING
Conditions: Chronic Limb-Threatening Ischemia
Interventions: DEVICE: Medistim MiraQ system with TTFM and L15 HFUS probes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: APG-2449 in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Cancer|Non Small Cell Lung Cancer|Esophageal Cancer|Ovarian Cancer|Malignant Pleural Mesothelioma
Interventions: DRUG: APG-2449
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Stepped Care for Chronic Pain in Iraq/Afghanistan Veterans (ESCAPE)
Status: COMPLETED
Conditions: Low Back Pain|Pain|Pain, Intractable
Interventions: BEHAVIORAL: Cognitive behavioral therapy|BEHAVIORAL: Pain self-management program|DRUG: Co-Analgesic Therapy|DRUG: Opioid Analgesics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of CIP-Isotretinoin in Patients With Severe Recalcitrant Nodular Acne
Status: COMPLETED
Conditions: Severe Nodular Acne
Interventions: DRUG: CIP-Isotretinoin|DRUG: Isotretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of DUR-928 Topical Solution in Subjects With Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: DUR-928 Topical Solution|DRUG: Vehicle Topical Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Consolidation Chemotherapy/Concurrent Chemo-radiotherapy for Inoperable Stage III Non-small Cell Lung Cancer (NSCLC)
Status: WITHDRAWN
Conditions: Stage III Non-small Cell Lung Cancer
Interventions: DRUG: Chemotherapy following concurrent Chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: U of A/ U of M Beans and Peas Health Claim Project
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Beans|DIETARY_SUPPLEMENT: Control (rice)|DIETARY_SUPPLEMENT: Peas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Watching a Television Show on the Liking of Snack Foods
Status: COMPLETED
Conditions: Measure Grams and Kcals of Snack Foods Consumed in Each Condition
Interventions: OTHER: Healthy Foods|OTHER: Unhealthy Snack Foods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Mobilization in Conjunction With Therapeutic Exercise in Participants With a History of Ankle Sprain
Status: COMPLETED
Conditions: Functional Deficits|Manipulation|Rehabilitation
Interventions: OTHER: High Velocity Low Amplitude mobilization|OTHER: Exercise Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study to Assess Safety, Tolerability and Pharmacokinetics of ASP2409 Following a Single Intravenous Dose in Patients With Rheumatoid Arthritis on Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Pharmacokinetics of ASP2409
Interventions: DRUG: ASP2409|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of CEA-Targeted CAR-T Therapy for Relapsed/Refractory CEA+ Cancer
Status: UNKNOWN
Conditions: Solid Tumor|Lung Cancer|Colorectal Cancer|Liver Cancer|Pancreatic Cancer|Gastric Cancer|Breast Cancer
Interventions: BIOLOGICAL: CEA CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Objective Brain Function Assessment of mTBI/Concussion in College Athletes
Status: COMPLETED
Conditions: Brain Injuries, Traumatic|Concussion, Mild|Concussion, Brain|Concussion, Intermediate|Concussion, Severe
Interventions: DEVICE: BrainScope Ahead 200iD|DEVICE: Advanced MRI Neuroimaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High-exchange ULTrafiltration to Enhance Recovery After Pediatric Cardiac Surgery
Status: RECRUITING
Conditions: Congenital Heart Disease
Interventions: PROCEDURE: Ultrafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Early Screening and Intervention for Gestational Diabetes Mellitus on Pregnancy Outcomes
Status: ACTIVE_NOT_RECRUITING
Conditions: Pregnancy Complications|Gestational Diabetes Mellitus in Pregnancy
Interventions: OTHER: early screening and intervention|OTHER: standard screening and intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Efficacy and Tolerance of Two Cosmetic Products in Subjects With Rosacea
Status: RECRUITING
Conditions: Rosacea|Redness|Telangiectasia|Flushing|Pustular Acne|Papule Pruritic
Interventions: OTHER: SCARCr tester 1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Bile Salt Stimulated Lipase (BSSL) as Replacement Therapy in Pasteurized Breast Milk for Preterm Infants
Status: COMPLETED
Conditions: Replacement Therapy in Preterm Infants
Interventions: DRUG: rhBSSL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Team COOL Pilot Study
Status: COMPLETED
Conditions: Multicomponent School Based Behavioral Intervention|Prevent Further Weight Gain and or Promote|Weight Loss Among Adolescents
Interventions: BEHAVIORAL: Team COOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Juvista in Scar Revision Surgery of Disfiguring Scars
Status: COMPLETED
Conditions: Cicatrix
Interventions: DRUG: Juvista (avotermin)|DRUG: Juvista (avotermin)|DRUG: Juvista (avotermin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Efficacy of the Synera Patch Compared to Naproxen Sodium for Epicondylitis of the Elbow
Status: COMPLETED
Conditions: Epicondylitis of the Elbow
Interventions: DRUG: Naproxen|DRUG: Synera patch twice daily|DRUG: Synera patch for 12hrs/day|DRUG: Naproxen|DRUG: Synera|DRUG: Synera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Nilotinib Combined With Mitoxantrone, Etoposide, and High-dose Cytarabine Induction Chemotherapy Followed by Consolidation for Patients With C-kit Positive Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: NOVE-HiDAC|DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Combining Temozolomide, Oncovin, Camptosar and Oral Antibiotic in Children and Adolescents With Recurrent Malignancy
Status: COMPLETED
Conditions: Lymphomas|Tumors
Interventions: DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Continuation Of a Study to Investigate the Effect of Thoracocentesis on Neural Respiratory Drive in Pleural Effusion
Status: RECRUITING
Conditions: Pleural Effusion
Interventions: OTHER: Surface parasternal eletromyogram|OTHER: Surface diaphragm electromyogram|OTHER: Parasternal muscle ultrasound|OTHER: Breathlessness assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Therapeutic ResistAnce and Clonal Evolution Assessed With Liquid Biopsy in ICIs Treated Primary Liver Cancer
Status: WITHDRAWN
Conditions: Primary Liver Cancer|Hepatocellular Carcinoma|Intrahepatic Cholangiocarcinoma|Combined Hepatocellular-cholangiocarcinoma
Interventions: OTHER: Observation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioequivalence Study of Torrent Pharmaceutical Limited's Pantoprazole Sodium 40 mg Delayed Release Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Torrent's Pantoprazole Sodium Delayed - Release Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Treatment of Chemotherapy Refractory Human Epidermalgrowth Factor Receptor-2( HER-2) Positive Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced HER-2 Positive Solid Tumors|Chemotherapy Refactory|HER-2 Antibody Inhibitor Therapy Refactory
Interventions: BIOLOGICAL: CART-HER-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Apremilast in Subjects With Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic Dermatitis
Interventions: DRUG: Apremilast|DRUG: Apremilast|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Steroid Use in Adolescent Idiopathic Scoliosis and Neuromuscular Scoliosis Patients
Status: NOT_YET_RECRUITING
Conditions: Neuromuscular Scoliosis|Adolescent Idiopathic Scoliosis
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: French-German Cohort Study to Determine Factors Associated With Weight Loss in Amyotrophic Lateral Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: OTHER: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Efficacy of an Intra-articular Injection of Autologous Microfat Combined With Autologous Platelet-enriched Plasma in the Treatment of Radiocarpal Osteoarthritis: a Randomized Controlled Non-inferiority Trial Versus Total Wrist Denervation (Established Standard Treatment).
Status: RECRUITING
Conditions: Arthrosis
Interventions: DRUG: Intra-articular injection of microfat and PRP|PROCEDURE: Total denervation of the wrist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Effectiveness Study of Major Glycemia-lowering Medications for Treatment of Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Comparative Effectiveness of Glycemia-lowering Medications
Interventions: DRUG: Sulfonylurea (glimepiride)|DRUG: DPP-4 inhibitor (sitagliptin)|DRUG: GLP-1 receptor agonist (liraglutide)|DRUG: Insulin (glargine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medical Masks vs N95 Respirators for COVID-19
Status: COMPLETED
Conditions: Coronavirus|N95|Medical Mask
Interventions: DEVICE: Medical Mask|DEVICE: N95 respirator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Smartphone Intervention for WIC Mothers to Improve Nutrition and Weight Gain During Pregnancy
Status: ACTIVE_NOT_RECRUITING
Conditions: Weight Gain During Pregnancy
Interventions: BEHAVIORAL: Healthy Beginnings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Kinesio Taping in Addition to Routine Physical Therapy on Pain, Range of Motion and Functional Disability in Patients With Upper Cross Syndrome
Status: COMPLETED
Conditions: Cervical Pain
Interventions: OTHER: Kinesio Taping Technique|OTHER: Routine Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Barrett's Dysplasia Detection Pilot Trial Using the NvisionVLE® Imaging System
Status: UNKNOWN
Conditions: Barrett's Esophagus
Interventions: DEVICE: NvisionVLE with Real Time Targeting|PROCEDURE: esophagogastroduodenoscopy (EGD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Anlotinib in Patients With Soft Tissue Sarcoma（STS）(ALTER0203)
Status: UNKNOWN
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Anlotinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Periodontal Therapy in Thalassemia Major Patients
Status: COMPLETED
Conditions: Thalassemia Major|Chronic Periodontitis
Interventions: PROCEDURE: Non surgical periodontal therapy|DRUG: Chemical plaque control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sofosbuvir Plus Ribavirin in Adults With Chronic HCV Infection
Status: COMPLETED
Conditions: Chronic HCV Infection
Interventions: DRUG: Sofosbuvir|DRUG: RBV|DRUG: PEG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NUTS for the Prevention of Cardiovascular Disease in Chinese Adults
Status: COMPLETED
Conditions: Cardiovascular Diseases|Dyslipidemias
Interventions: DIETARY_SUPPLEMENT: Walnuts 30 grams|DIETARY_SUPPLEMENT: Walnuts 60 grams
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy and Cetuximab or Bevacizumab in Treating Patients With Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin|DRUG: irinotecan hydrochloride|BIOLOGICAL: bevacizumab|BIOLOGICAL: cetuximab|DRUG: capecitabine|GENETIC: mutation analysis|GENETIC: gene expression analysis|OTHER: laboratory biomarker analysis|OTHER: immunohistochemistry staining method|GENETIC: nucleic acid sequencing|GENETIC: protein expression analysis|GENETIC: polymerase chain reaction|GENETIC: DNA analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Neuropsychological Alteration of Decision-making Abilities on the Functioning of Patients With Eating Disorders
Status: UNKNOWN
Conditions: Eating Disorder
Interventions: BEHAVIORAL: Ambulatory cares in a day-hospital (University Hospital of Montpellier) specialized in the evaluation of eating disorders
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of the Digital Multi-domain Cognitive Intervention in High-risk Populations for Dementia
Status: RECRUITING
Conditions: Cognitive Dysfunction
Interventions: BEHAVIORAL: Multi-domain Cognitive Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the PD-L1xCD27 Bispecific Antibody CDX-527 in Patients With Advanced Malignancies
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Breast Cancer|Gastric Cancer|Renal Cell Carcinoma|Ovarian Cancer|Primary Peritoneal Carcinoma|Fallopian Tube Cancer|Cholangiocarcinoma|Bladder Urothelial Carcinoma|MSI-H Colorectal Cancer|Esophageal Cancer|Hepatic Cancer|Head and Neck Cancer|Other Solid Tumors
Interventions: DRUG: CDX-527
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab and Olaparib for the Treatment of Prostate Cancer in Men Predicted to Have a High Neoantigen Load
Status: ACTIVE_NOT_RECRUITING
Conditions: Biochemically Recurrent Prostate Carcinoma|Prostate Adenocarcinoma
Interventions: BIOLOGICAL: Durvalumab|DRUG: Olaparib|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Gastric pH on Acalabrutinib Pharmacokinetics (PK) in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Acalabrutinib|DRUG: SmartPill®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tizanidine and Pain After Herniorrhaphy
Status: COMPLETED
Conditions: Unilateral Inguinal Hernia
Interventions: DRUG: Tizanidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Compare and Evaluate the Safety and Pharmacokinetic of CKD-501, D745, and D150 for Healthy Subjects in Fed State.
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Test: CKD-383, Reference1: Duvie Tab. 0.5mg, Reference2: Jardiance tablets 25 mg, Reference3: GLUCOPHAGE XR TAB. 1000MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 24-hour Oral Morphine Equivalent Based Opioid Prescribing After Surgery
Status: COMPLETED
Conditions: Opioid Use
Interventions: OTHER: Arm 1 Prescription As Usual|OTHER: Arm 2 Prescription Tool Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Safety, Tolerability, and Pharmacokinetic Study of NIP292 in Healthy Normal Subjects
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: NIP292 tablet|DRUG: NIP292 tablet|DRUG: NIP292 tablet|DRUG: NIP292 tablet|DRUG: NIP292 tablet|DRUG: NIP292 tablets|DRUG: NIP292 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COLchicine Versus Ruxolitinib and Secukinumab in Open-label Prospective Randomized Trial in Patients With COVID-19
Status: COMPLETED
Conditions: COVID 19
Interventions: DRUG: Colchicine|DRUG: Ruxolitinib 5 MG|DRUG: Secukinumab 150 MG/ML Subcutaneous Solution [COSENTYX]|OTHER: standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Oxomemazine, Guaifenesin and Potassium Iodate Versus Guaifenesin Monotherapy in Acute Cough Treatment
Status: COMPLETED
Conditions: Cough
Interventions: DRUG: Syrup of oxomemazine, guaifenesin and potassium iodate|DRUG: Syrup of guaifenesin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Effect of a Multidisciplinary Telematics Approach for Chronic Non-specific Low Back Pain: a Randomized, Open-label, Controlled, Pilot Clinical Trial. Study Protocol
Status: COMPLETED
Conditions: Low Back Pain
Interventions: BEHAVIORAL: physical rehabilitation/physiotherapy and psychosocial group sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT