pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Autologous Platelet Rich Plasma Intraovarian Infusion for Poor Responders
Status: RECRUITING
Conditions: Poor Response to Ovulation Induction|Infertility, Female|Ovarian Insufficiency|Ovarian Failure|Reproductive Sterility|Ovary; Anomaly
Interventions: BIOLOGICAL: Autologous platelet rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy, Safety, And Tolerability Of Donepezil HCl (E2020) In Patients With CADASIL Who Have Cognitive Impairment
Status: COMPLETED
Conditions: Cognitive Impairment
Interventions: DRUG: Aricept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy With or Without Huaier Granule in Treating Women With Locally Advanced Breast Cancer That Can Be Removed By Surgery
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Huaier Granule|DRUG: Epirubicin|DRUG: Docetaxel|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CE-MRA Using Gadovist in Comparison to IA DSA Using Ultravist
Status: UNKNOWN
Conditions: Angiography, Digital Subtraction|Magnetic Resonance Angiography
Interventions: PROCEDURE: CE-MRA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hase 1/2 Study of HS-10375 in Patients With Advanced or Metastatic Non-Small-Cell Lung Cancer(NSCLC)
Status: RECRUITING
Conditions: Advanced or Metastatic NSCLC
Interventions: DRUG: HS-10375
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Nutritional Management Algorithm in Older Patients With Locally Advanced Esophageal Cancer
Status: COMPLETED
Conditions: Localized Stage I-III Esophageal Cancer|Gastroesophageal Junction Cancer
Interventions: OTHER: nutritional and functional assessments
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Immediate Changes After Manual Therapy in Patients With Non-specific Back Pain
Status: COMPLETED
Conditions: Back Pain
Interventions: OTHER: Neuro-lymphatic treatment|OTHER: Articulatory spinal manual therapy|OTHER: Articulatory costal Manual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation for the Prevention of Acute Respiratory Infections: a RCT in Young Finnish Men
Status: COMPLETED
Conditions: Vitamin D Deficiency|Respiratory Tract Infections
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Multi-center, Phase II Study of the Safety, Tolerability and Bioactivity of Repeated Intravitreal Injections of iCo-007 as Monotherapy or in Combination With Ranibizumab or Laser Photocoagulation in the Treatment of Diabetic Macular Edema (the iDEAL Study)
Status: TERMINATED
Conditions: Diabetic Macular Edema
Interventions: DRUG: iCo-007 350 mcg|DRUG: iCo-007 700 mcg|DRUG: iCo-007 350 mcg and Laser|DRUG: Ranibizumab and iCo-007 350 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study Testing Herbal Extract on Metabolic Parameters in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: OTHER: herbal extract; root of woody shrub grown in India/Sri-Lanka
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Transmission of Coronavirus Disease 2019 (COVID19) in Crowded Environments
Status: COMPLETED
Conditions: Covid19|Sars-CoV-2 Infection
Interventions: OTHER: STOPCOV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reservoir-Based Polymer-Free Amphilimus-Eluting Stent Versus Polymer-Based Everolimus-Eluting Stent in Diabetic Patients
Status: UNKNOWN
Conditions: Coronary Artery Disease|Diabetes Mellitus
Interventions: DEVICE: Polymer-Based Everolimus-Eluting Stent|DEVICE: Polymer-Free Amphilimus-Eluting Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Cocaine Dependence: Comparison of Three Doses of Dextro-Amphetamine Sulfate and Placebo
Status: COMPLETED
Conditions: Cocaine-Related Disorders
Interventions: DRUG: Dextro-Amphetamine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Efficacy of Anti-staphylococcal Phages in the Management of Infected Foot Ulcers in Diabetes
Status: WITHDRAWN
Conditions: Diabetes|Diabetic Foot|Diabetic Foot Infection
Interventions: DRUG: Phage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Web-Delivered Interventions for Blood Sugar Control for Individuals With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Multicomponent online program|BEHAVIORAL: Breath meter|BEHAVIORAL: Text messages|BEHAVIORAL: Diet-appropriate foods and cookbooks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ib/IIa Clinical Study of ApTOLL for the Treatment of Acute Ischemic Stroke
Status: COMPLETED
Conditions: Stroke|Acute Stroke|Ischemic Stroke
Interventions: DRUG: ApTOLL|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Dense Rituximab for High Risk Newly Diagnosed Acute Immune Thrombocytopenic Purpura
Status: RECRUITING
Conditions: Immune Thrombocytopenic Purpura
Interventions: DRUG: rituxan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Treatment of Cognitive Impairment and Insomnia in Cancer Survivors
Status: COMPLETED
Conditions: Cancer|Insomnia|Cognitive Impairment
Interventions: BEHAVIORAL: Cognitive Behaviour Therapy for Insomnia (CBT-I)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Celotres for Improvement in Wound Healing and Resulting Scar Consequences Following Suturing of a Wound
Status: COMPLETED
Conditions: Scar
Interventions: OTHER: Celotres|OTHER: Surgical Closure by Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Calcium and Vitamin D Supplementation During Marine Corps Training
Status: COMPLETED
Conditions: Nutrition Status|Bone Health
Interventions: DIETARY_SUPPLEMENT: Calcium/Vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transcranial Magnetic Stimulation (TMS) for Suicidal Ideation
Status: UNKNOWN
Conditions: Depressive Episode|Posttraumatic Stress Disorder|Traumatic Brain Injury
Interventions: DEVICE: Transcranial Magnetic Stimulation|DEVICE: Transcranial Magnetic Stimulation - Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study Between Two Formulations Of Sildenafil Citrate
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: sildenafil citrate 100 mg CT|DRUG: sildenafil citrate 100 mg CT|DRUG: Viagra®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CB-17-08 Augmented Endoscopy System for Mucosal Lesion Detection During Colonoscopy for Colon Rectal Cancer.
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DEVICE: CB-17-08 CADe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Erector Spinae Plane Block on Postoperative Delirium in Patients Undergoing Lumbar Spine Surgery
Status: UNKNOWN
Conditions: Postoperative Delirium
Interventions: DIAGNOSTIC_TEST: CAM ICU test|DIAGNOSTIC_TEST: MOCA test|DIAGNOSTIC_TEST: brief pain test|DIAGNOSTIC_TEST: VAS scale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cisplatin/Etoposide/Radiotherapy Followed by Consolidation Sorafenib for Inoperable Stage III Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Cisplatin|DRUG: Etoposide|PROCEDURE: Radiotherapy|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of Homebound Stem Cell Transplantation
Status: RECRUITING
Conditions: Plasma Cell Dyscrasia
Interventions: BEHAVIORAL: Home monitoring teleconsult visits|BEHAVIORAL: Patient Reported Outcomes (PRO)|BEHAVIORAL: Caregiver Reported Outcomes instruments
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: SCREENING
Clinical trial: AGN-193408 SR in the Treatment of Open-angle Glaucoma or Ocular Hypertension
Status: RECRUITING
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: AGN-193408 SR|OTHER: Lumigan|OTHER: Sham Administration|OTHER: Lumigan Vehicle|DRUG: AGN-193408 SR|OTHER: Sham Administration|OTHER: Lumigan Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of a Vaccine in Combination With Beta-glucan in People With Neuroblastoma
Status: RECRUITING
Conditions: Neuroblastoma|High-risk Neuroblastoma|Metastatic Neuroblastoma
Interventions: BIOLOGICAL: OPT-821 (QS-21)|DIETARY_SUPPLEMENT: oral β-glucan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cash Transfers on Severe Acute Malnutrition
Status: COMPLETED
Conditions: Severe Malnutrition
Interventions: OTHER: Outpatient therapeutic program, counseling and cash transfer|OTHER: Outpatient therapeutic program and counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparison of Surgical Outcome Following Drug-induced Sleep Endoscopic Diagnosis Using Propofol or Dexmedetomidine for Sedation : A Prospective Randomized Trial
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Propofol|DRUG: propofol-remifentanil|DRUG: Dexmedetomidine-remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety and Pharmacokinetics of Double-Blind S-707106 Alone and in Combination With Open-Label Metformin in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: S-707106|DRUG: Placebo|DRUG: Metformin, S-707106 plus metformin|DRUG: Metformin, placebo plus metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Myfortic or CellCept Gastrointestinal Effects in African American Kidney Recipients
Status: TERMINATED
Conditions: Transplants and Implants
Interventions: DRUG: Enteric coated mycophenolate sodium|DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-dose Glucocorticoid Vasculitis Induction Study
Status: UNKNOWN
Conditions: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis|Microscopic Polyangiitis|Wegener Granulomatosis
Interventions: DRUG: Rituximab|DRUG: Glucocorticoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Of The Efficacy Of Corticosteroids In Patients With An Acute Exacerbation Of Chronic Obstructive Pulmonary Disease Receiving Ventilator Support
Status: TERMINATED
Conditions: COPD
Interventions: DRUG: intravenous methylprednisolone|OTHER: intravenous normal saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Urostomy Bags (2-piece).
Status: COMPLETED
Conditions: Urostomy Patent
Interventions: DEVICE: Convatec Uro 2-piece|DEVICE: SenSura Uro 2-piece
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Sebum Excretion in Neonates of Women With Polycystic Ovary Syndrome (PCOS)
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: OTHER: Sebutape
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Interest of Bilateral Basic Tongue Mucosectomy Assisted by Robot or Laser in Combination With Tonsillectomy in the Assessment of Prevalent Cervical Lymphadenopathy
Status: RECRUITING
Conditions: Cancer of Head and Neck|Adenopathy
Interventions: PROCEDURE: bilateral mucosectomy + tonsillectomy|PROCEDURE: tonsillectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nanoparticles Analysis in Lung and Bronchi During Various Pulmonary Interstitial Diseases and Relationships With Their Aetiology
Status: COMPLETED
Conditions: Interstitial Lung Diseases
Interventions: OTHER: BAL|OTHER: BW|OTHER: EAC|OTHER: blood specimen|OTHER: Urine specimen
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Influence of Aliskiren on Albuminuria After Kidney Transplantation
Status: COMPLETED
Conditions: Albuminuria
Interventions: DRUG: aliskiren|DRUG: losartan|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab in Ovarian Cancer Patients With Disease at Second-Look Surgery
Status: RECRUITING
Conditions: Malignant Neoplasms of Female Genital Organs|Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: iGlucose® Remote Patient Monitoring Device as an Adjunct to Routine Glucose Meter Devices for Glycemic Management and Control in Gestational Diabetes
Status: RECRUITING
Conditions: Gestational Diabetes|Type2 Diabetes|Pregnancy in Diabetic
Interventions: DEVICE: iGlucose Smart Meter System|DEVICE: Routine Care-RX meter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Open-label Randomized Study of Lactofiltrum in Women With Bacterial Vaginosis
Status: UNKNOWN
Conditions: Bacterial Vaginosis
Interventions: DRUG: Lactofiltrum + Metronidazole|DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Exercise Training on Ischemia With Non-Obstructive Coronary Arteries (INOCA): The ExINOCA Study
Status: NOT_YET_RECRUITING
Conditions: Coronary Microvascular Disease|CMD
Interventions: OTHER: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an Instability Training Program Using Global Versus Selective Instability Devices
Status: COMPLETED
Conditions: Balance Instability Training
Interventions: OTHER: Proprioception training exercise plan with BOSU|OTHER: Proprioception training exercise plan with Blackboard (BB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: "Let's Get Organized" in Adult Psychiatric/Habilitation Care
Status: COMPLETED
Conditions: Neurodevelopmental Disorders|Mental Disorder
Interventions: BEHAVIORAL: Let's Get Organized group intervention|DEVICE: Individual Occupational Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Medication to Improve Weight Loss in Suboptimal Early Responders to Behavioral Treatment
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Behavioral Treatment|DRUG: Placebo|DRUG: Phentermine 15 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The FAVOR III China Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease|Myocardial Ischaemia|Coronary Circulation|Coronary Stenosis|Percutaneous Coronary Intervention
Interventions: DIAGNOSTIC_TEST: QFR|DIAGNOSTIC_TEST: Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Anwar and Melles Techniques in Deep Anterior Lamellar Keratoplasty (DALK) for Keratoconus Patients
Status: COMPLETED
Conditions: Keratoconus
Interventions: PROCEDURE: Anwar|PROCEDURE: Melles
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Efficacy Study of Methenamine + Methylthioninium Chloride vs Phenazopyridine for the Symptomatic Control of Dysuria
Status: COMPLETED
Conditions: Dysuria
Interventions: DRUG: Methenamine and Methylthioninium chloride|DRUG: Phenazopyridine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Influence of Intraperitoneal Insufflation of CO2 by Laparoscopy on the Short-term Evolution of Premature Infants With Ulcerative Necrotizing Enterocolitis
Status: RECRUITING
Conditions: Preterm Birth|Enterocolitis, Necrotizing
Interventions: PROCEDURE: laparotomy|PROCEDURE: Laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Water Exchange Method on Adenoma Miss Rates in Patients Undergoing Selective Polypectomy
Status: UNKNOWN
Conditions: Adenoma
Interventions: OTHER: Water exchange (WE) method|OTHER: Air insufflation (AI) method.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Surgical Pembro +/- Olaparib w TMZ for rGBM
Status: RECRUITING
Conditions: Glioblastoma|Recurrent Glioblastoma
Interventions: DRUG: Pembrolizumab|DRUG: Olaparib|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term Atorvastatin's Effect on Acute Kidney Injury Following Cardiac Surgery
Status: COMPLETED
Conditions: Acute Kidney Injury|Post-Operative Delirium|Icu Delirium|Acute Renal Failure|Delirium
Interventions: DRUG: atorvastatin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Campath-1H for Treating Adult T-Cell Leukemia/Lymphoma
Status: COMPLETED
Conditions: Acute T-Cell Leukemia-Lymphoma
Interventions: BIOLOGICAL: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors
Status: SUSPENDED
Conditions: Neurofibromatosis 2|Vestibular Schwannoma|Meningioma|Ependymoma|Glioma
Interventions: DRUG: Selumetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bilateral Ultrasound Guided Pectoralis Nerve Block Induces Hemodynamic Stability With Reducing Systemic Stress Response for Off-pump Coronary Artery Bypass Graft
Status: COMPLETED
Conditions: Analgesic Effects|Systemic Stress Response|Hemodynamic Stability
Interventions: DRUG: Bilateral Ultrasound Guided Pectoralis Nerve Block.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Obese Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Obesity|Diabetes Mellitus, Non-Insulin-Dependent|Obesity in Diabetes
Interventions: DRUG: Rimonabant (SR141716)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Casopitant (Oral) And ZOFRAN To Prevent Postoperative Nausea And Vomiting In Women
Status: COMPLETED
Conditions: Nausea and Vomiting, Postoperative
Interventions: DRUG: GW679769 (casopitant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Randomized Optical Coherence Tomography Oslo tRial
Status: TERMINATED
Conditions: Myocardial Infarction|Angina
Interventions: OTHER: Optical coherence tomography|RADIATION: Coronary angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of HC-7366 to Establish the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D)
Status: TERMINATED
Conditions: Squamous Cell Carcinoma of Head and Neck|Colo-rectal Cancer|Non Small Cell Lung Cancer|Transitional Cell Carcinoma of the Bladder|Other Solid Tumors|Clear Cell Renal Cell Carcinoma
Interventions: DRUG: HC-7366
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cholecalciferol Supplementation on Disease Activity, Fatigue and Bone Mass on Juvenile Systemic Lupus Erythematosus.
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Cholecalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Telephone and Web-based Teen Tobacco Cessation in HMOs
Status: COMPLETED
Conditions: Tobacco Use
Interventions: BEHAVIORAL: Telephone counseling + interactive website = more abstinence|BEHAVIORAL: Behavioral: interactive website
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Extension Study To Investigate Long Term Safety, Tolerability And Efficacy Of Pf-02545920 In Subjects With Huntington's Disease Who Completed Study A8241021
Status: TERMINATED
Conditions: Huntington's Disease
Interventions: DRUG: 20 mg BID of PF-02545920
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SystemCHANGE™ Intervention on Medication Adherence in Older Adults With Heart Failure
Status: COMPLETED
Conditions: Medication Adherence|Heart Failure|Aging
Interventions: BEHAVIORAL: SystemCHANGE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Phase II Trial of SBRT + or - IMRT in Treatment of Patients With Clinically Confined Prostate Adenocarcinoma
Status: COMPLETED
Conditions: Prostate Adenocarcinoma
Interventions: RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Study to Evaluate Efficacy and Safety of DSC127 in Diabetic Foot Ulcers
Status: TERMINATED
Conditions: Diabetic Foot Ulcers
Interventions: DRUG: DSC127|DRUG: placebo vehicle gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wrist Arthroscopy During Surgical Treatment of Distal Radius Fractures
Status: NOT_YET_RECRUITING
Conditions: Fracture|Radius Fracture Distal
Interventions: PROCEDURE: Wrist arthroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intentional Rejection of the Donor Graft Using Recipient Leukocyte Infusion(s) Following Nonmyeloablative Allogeneic Stem Cell Transplant
Status: TERMINATED
Conditions: Non Hodgkin's Lymphoma|Hodgkin Disease|Multiple Myeloma
Interventions: OTHER: Fludarabine and total body irradiation|RADIATION: Total body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of Duloxetine With Placebo in Patients With Chronic Low Back Pain With a Radicular Component
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DRUG: Duloxetine|DRUG: Duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Otago Home-Based Exercise Program in Community-Dwelling Older Women (METCOHEP Study)
Status: TERMINATED
Conditions: Balance Impairment|Risk of Falling
Interventions: OTHER: Warm-up and Cool-down Program|OTHER: Strengthening Exercises|OTHER: Balance Exercises|OTHER: Otago Home Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of the Consumption of SEAweed Biomass Versus PROtein Isolates on Postprandial Satiety and Metabolism
Status: ACTIVE_NOT_RECRUITING
Conditions: Nutrition, Healthy
Interventions: OTHER: Soy control|OTHER: Intervention (Laver/nori (Porphyra umbillicus) macroalgae whole biomass)|OTHER: Intervention (Laver/nori macroalgae (Porphyra umbillicus) protein isolates)|OTHER: Intervention (Chlorella microalgae (Chlorella vulgaris) whole biomass)|OTHER: Intervention (Chlorella microalgae (Chlorella vulgaris) protein isolates)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Preoperative Carbohydrate Drink Prior to Elective Caesarean Section
Status: UNKNOWN
Conditions: Fasting|Cesarean Delivery Affecting Fetus|Glucose, Low Blood
Interventions: DIETARY_SUPPLEMENT: Carbohydrate drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise on Thoracic Aneurysms
Status: WITHDRAWN
Conditions: Thoracic Aortic Aneurysm
Interventions: DEVICE: Exercise group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fascia Iliaca Block in the Emergency Department for Analgesia After Femoral Neck Fracture
Status: COMPLETED
Conditions: Femoral Neck Fracture
Interventions: PROCEDURE: Fascia iliaca block|PROCEDURE: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sciatica Epidural Radiculopathy Experimental New Interventional TherapY Clonidine Micropellet
Status: TERMINATED
Conditions: Lumbosacral Radiculopathy
Interventions: DRUG: Clonidine Micropellets|DEVICE: Tuohy epidural needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerance and Efficacy of an Oral Nutritional Supplement in Lung Cancer Patients
Status: TERMINATED
Conditions: Cachexia|Cancer
Interventions: DIETARY_SUPPLEMENT: oral nutritional supplement, food for special medical purposes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating Two Dose Levels of Targretin Capsules in Participants With Refractory Cutaneous T-Cell Lymphoma (CTCL)
Status: COMPLETED
Conditions: Refractory Cutaneous T-cell Lymphoma
Interventions: DRUG: Bexarotene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block for Postoperative Analgesia Management Following Video Assisted Thoracic Surgery
Status: COMPLETED
Conditions: Lung Cancer
Interventions: OTHER: Erector spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of RBM-007 Alone and RBM-007 With Eylea® in Subjects With Wet Age-related Macular Degeneration
Status: COMPLETED
Conditions: Exudative Age-related Macular Degeneration
Interventions: DRUG: RBM-007 Injectable Solution|DRUG: Aflibercept|DRUG: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Breast Density's Value in Imaging - A Comparative Effectiveness Study
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: OTHER: Screening digital mammography|OTHER: Screening digital breast tomosynthesis|OTHER: Screening breast magnetic resonance imaging|OTHER: Diagnostic mammography|OTHER: Pre-operative breast magnetic resonance imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The EPIC Trial The Elderly Patient Individualized Chemotherapy Trial
Status: UNKNOWN
Conditions: Stage IV, NSCLC|Lung Neoplasms|Bronchial Neoplasms|Carcinoma, Bronchogenic|Lung Diseases|Neoplasms|Respiratory Tract Diseases|Respiratory Tract Neoplasms|Thoracic Neoplasms
Interventions: DRUG: Carboplatin|DRUG: Gemcitabine|DRUG: Pemetrexed|DRUG: Docetaxel|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LURN: Urinary Urgency Phenotyping Protocol
Status: RECRUITING
Conditions: Lower Urinary Tract Symptoms
Interventions: OTHER: Observational|OTHER: Observational Controls|OTHER: Central Sensitization|OTHER: Physical Activity and Sleep Tracker|OTHER: Physical Activity and Sleep Tracker Controls|OTHER: Organ-Based|OTHER: Qualitative Assessment of Patients with Urinary Urgency
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CyberHeart's Cardiac Arrhythmia Ablation Treatment: Patients With Refractory Ventricular Tachycardia/Fibrillation
Status: COMPLETED
Conditions: Tachycardia, Ventricular
Interventions: DEVICE: CyberHeart System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting the Well Being of Caregivers Via Telehealth
Status: RECRUITING
Conditions: Caregivers|Parents
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy (ACT)|BEHAVIORAL: Culturally Informed Cognitive Behavioral Therapy (CICBT), Individual|BEHAVIORAL: Culturally Informed Cognitive Behavioral Therapy (CICBT), Group|BEHAVIORAL: Dialectical Behavioral Therapy (DBT)|BEHAVIORAL: Durand Sleep Intervention|BEHAVIORAL: RUBI Intervention|BEHAVIORAL: Naturalistic Communication Intervention (NCI)|BEHAVIORAL: Self-Guided Resources|BEHAVIORAL: Participation Enhancement Intervention (PEI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Must Cannulation Technique of Vascular Access in Patients Undergoing Haemodialysis: Contributions for a Safe Nursing Intervention
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Hemodialysis|Vascular Access Complication|Hemodialysis Access Failure|Arteriovenous Fistula
Interventions: PROCEDURE: CT MuST|PROCEDURE: Rope-ladder cannulation technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incomplete Response in Late-Life Depression: Getting to Remission With Buprenorphine
Status: COMPLETED
Conditions: Major Depressive Disorder|Depression
Interventions: DRUG: venlafaxine|DRUG: buprenorphine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Salivary Biomarkers of Gastroesophageal Reflux in Infants
Status: RECRUITING
Conditions: Gastroesophageal Reflux in Infants
Interventions: DIAGNOSTIC_TEST: salivary markers
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Traumatic Optic Neuropathy Treatment Trial 2
Status: COMPLETED
Conditions: Traumatic Optic Neuropathy
Interventions: DRUG: Recombinant human erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ramucirumab (LY3009806) in Combination With Erlotinib in Previously Untreated Participants With EGFR Mutation-Positive Metastatic NSCLC (RELAY)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Non-Small Cell Lung Cancer
Interventions: DRUG: Ramucirumab|DRUG: Placebo|DRUG: Erlotinib|DRUG: Gefitinib|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prostate-Rectal Separation With PEG Hydrogel and Its Effect on Decreasing Rectal Dose
Status: COMPLETED
Conditions: Cancer of the Prostate
Interventions: DEVICE: PEG Hydrogel (SpaceOAR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endomyocardial Botulinum Toxin Injection in Patients With Persistent Atrial Fibrillation
Status: UNKNOWN
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: Pulmonary vein isolation|PROCEDURE: Linear Lesion Ablation|DRUG: BT injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tanespimycin in Treating Patients With Inoperable Locoregionally Advanced or Metastatic Thyroid Cancer
Status: COMPLETED
Conditions: Recurrent Thyroid Cancer|Stage IV Follicular Thyroid Cancer|Stage IV Papillary Thyroid Cancer|Thyroid Gland Medullary Carcinoma
Interventions: DRUG: tanespimycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Ascorbic Acid and Tocopherol for Depression in Elderly.
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Ascorbic Acid|DRUG: Alpha tocopherol|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Functional Chewing Training on Tongue Thrust and Drooling in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Mastication Disorder
Interventions: OTHER: Functional Chewing Training|OTHER: Classical Oral Motor Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Folic Acid Supplementation in Calcific Aortic Valve Disease
Status: NOT_YET_RECRUITING
Conditions: Calcification of Aortic Valve|Aortic Valve Stenosis
Interventions: DRUG: Folic Acid Oral Tablet|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of a New Agent for Treatment of Advanced Stage Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasm
Interventions: DRUG: Sagopilone (ZK 219477)|DRUG: Sagopilone (ZK 219477)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of a Peripheral Nerve Stimulation
Status: RECRUITING
Conditions: Complications; Prosthesis, Nervous System, Peripheral, Pain
Interventions: DEVICE: Percutaneous peripheral nerve stimulation system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: SJS/TEN or Other Cutaneous Adverse Eevents Induced by Immune Checkpoint Inhibitors (ICIs) vs. Non-ICIs
Status: COMPLETED
Conditions: Immune Checkpoint Inhibitor-Induced Dermatitis|Stevens-Johnson Syndrome, Drug-Induced|Toxic Epidermal Necrolysis Due to Drug
Interventions: OTHER: Observational studies do not require intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy and Safety of Retrovir in Patients Infected With HIV Who Are Asymptomatic (CDC Group II) or Have Persistent Generalized Lymphadenopathy (CDC Group III)
Status: COMPLETED
Conditions: Lymphatic Disease|HIV Infections
Interventions: DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Novel Application of Simulation for Providers to Overcome Decisional Gaps in High-risk Prescribing
Status: COMPLETED
Conditions: Medication Administered in Error|Antipsychotics and Neuroleptics Toxicity
Interventions: OTHER: Simulation|OTHER: Online educational training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Saccharomyces Boulardii in Patients in the Waiting List for Liver Transplant
Status: COMPLETED
Conditions: Liver Cirrhosis
Interventions: DRUG: Saccharomyces boulardii
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of GANFORT® UD in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) in a Medical Setting
Status: COMPLETED
Conditions: Glaucoma, Primary Open Angle|Ocular Hypertension
Interventions: DRUG: Fixed Combination Bimatoprost and Timolol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Tissue Engineered Endothelial Keratoplasty
Status: UNKNOWN
Conditions: Mild to Moderate Corneal Endothelial Decompensation|Bullous Keratopathy|Fuchs' Endothelial Dystrophy|Post-surgical Corneal Decompensation (Irreversible)
Interventions: OTHER: TE-EK treatment group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of a Rivaroxaban-based Strategy With an Antiplatelet-based Strategy Following Successful TAVR for the Prevention of Leaflet Thickening and Reduced Leaflet Motion as Evaluated by Four-dimensional, Volume-rendered Computed Tomography (4DCT)
Status: COMPLETED
Conditions: Aortic Valve Stenosis|Cardiovascular Diseases|Heart Valve Diseases|Ventricular Outflow Obstruction|Thrombosis
Interventions: DRUG: Acetylsalicylic acid|DRUG: Clopidogrel|DRUG: Rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Accessing the Driving Skills After the Endoscopy of Intravenous Anesthesia by Driving Simulator
Status: COMPLETED
Conditions: Driving
Interventions: PROCEDURE: Endoscopy of Intravenous Anesthesia|DEVICE: Driving Simulator|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pulmonary Rehabilitation and Inspiratory Muscle Training (IMT) for Patients Following Lung Transplantation
Status: UNKNOWN
Conditions: Lung Transplantation
Interventions: BEHAVIORAL: Conventional or regular pulmonary rehabilitation program alone|DEVICE: very low load IMT (sham IMT) alone|DEVICE: Conventional or regular pulmonary rehabilitation program + targeted inspiratory resistive or threshold IMT|DEVICE: Targeted inspiratory resistive or threshold IMT alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of an Intervention to Increase Post-abortion LARC Uptake.
Status: COMPLETED
Conditions: Post Abortion Contraception
Interventions: BEHAVIORAL: Contraceptive education prior to abortion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The BANGALORE Study; Combination of Berberine, Lipoic Acid, and Picrorhiza
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: CAR-191|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lactobacillus Reuteri DSM 17938 in Gut Microbiota Development in Infant Born by Caesarean Section
Status: COMPLETED
Conditions: Dysbiosis|Prophylaxis
Interventions: DIETARY_SUPPLEMENT: BioGaia Protectis drops|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ISP-TACE Versus TACE for HCC With PVTT
Status: COMPLETED
Conditions: HCC|Portal Vein Tumor Thrombosis
Interventions: DRUG: ethiodized oil; doxorubicin;Gelfoam;|DEVICE: stent; idoine-125
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Resection Location of Rectum in Laparoscopic Surgery for Slow Transit Constipation
Status: UNKNOWN
Conditions: Slow Transit|Constipation
Interventions: PROCEDURE: Laparoscopic total colectomy + low resection of rectum|PROCEDURE: Laparoscopic total colectomy + High resection of rectum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using CHWs and HPV Home Tests to Increase Cervical Cancer Screening in Minority Populations
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: BEHAVIORAL: CHW Outreach and HPV Self-sampling|BEHAVIORAL: CHW Outreach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Study Assessing the Long-Term Safety and Tolerability of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration
Status: TERMINATED
Conditions: Macular Degeneration, Age-Related|Geographic Atrophy
Interventions: DRUG: Galegenimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HAP/VAP Diagnosis in Critically Ill Septic Patients Using a Multiplex PCR Array
Status: RECRUITING
Conditions: HAP - Hospital Acquired Pneumonia|VAP - Ventilator Associated Pneumonia
Interventions: PROCEDURE: Lower tract respiratory samples|DIAGNOSTIC_TEST: Multiplex PCR assay (Film-array Pneumonia Panel Plus)|DIAGNOSTIC_TEST: Lower respiratory tract standard culture|DIAGNOSTIC_TEST: Blood sample standard culture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ACURATE neo2™ Post Market Clinical Follow up Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Valve Stenosis|Aortic Valve Calcification|Aortic Diseases
Interventions: DEVICE: Transcatheter Aortic Valve Implantation/Replacement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mesenteric Sparing Surgery in Laparoscopic Colorectal Resection for Endometriosis
Status: UNKNOWN
Conditions: Endometriosis|Bowel Endometriosis|Constipation
Interventions: PROCEDURE: Mesenteric vascular and nerve sparing surgery in laparoscopic segmental colorectal resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p