pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Fibrin Sealant VH S/D 500 S-apr in Hepatic Resection
Status: COMPLETED
Conditions: Bleeding (Oozing) in Hepatic Resection
Interventions: DRUG: Fibrin Sealant (FS) VH S/D 500 s-apr|OTHER: Manual compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of VIRTUAL SFCAMINA STUDY
Status: UNKNOWN
Conditions: Chronic Fatigue Syndrome
Interventions: BEHAVIORAL: TAU + multicomponent treatment VIRTUAL SFCAMINA|BEHAVIORAL: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Playfulness in Online and Face-to-face Interactions, From Adulthood to Aging
Status: COMPLETED
Conditions: Aging|Cognitive Function 1, Social|Social Behavior|Aging Well|Executive Function
Interventions: BEHAVIORAL: Playful interactions in an online format|BEHAVIORAL: An active control condition in a face-to-face format|BEHAVIORAL: An active control condition in an online format|BEHAVIORAL: Playful interactions in a face to face format
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Role of PKC Activation in the Immune-inflammatory Mechanism of Major Depressive Depression
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Escitalopram+golimumab|DIETARY_SUPPLEMENT: Escitalopram+Calcium Tablet|DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Two Therapeutic Strategies for the Maintenance of Remission in Patients With Ulcerative Colitis
Status: UNKNOWN
Conditions: Colitis, Ulcerative
Interventions: DRUG: Azathioprine|DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AZD7325 Japan Multiple Ascending Dose (MAD) Study
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: AZD7325|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gardasil Versus Cervarix in the Treatment of Warts
Status: COMPLETED
Conditions: Verruca Viral
Interventions: DRUG: Quadrivalent Human Papillomavirus (Types 6,11,16,18) Recombinant Vaccine|DRUG: Bivalent Human Papilloma Virus Vaccine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Blood Sampling With a Sterile and Dry Puncture Area
Status: UNKNOWN
Conditions: Ultrasound|Sterile Puncture Area|Blood Sampling
Interventions: DEVICE: A product type of the modified commercial drape Tegaderm (R)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Allogeneic Hematopoietic Stem Cell Transplantation (NST) for Patients With Systemic Sclerosis
Status: TERMINATED
Conditions: Scleroderma
Interventions: BIOLOGICAL: Hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Cardiac Pacing to Initiate Cardiac Remodeling in Heart Failure
Status: COMPLETED
Conditions: Cardiomyopathies|Heart Rate|Conditioning
Interventions: OTHER: novel atrial pacing approach|OTHER: sham pacing approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare PK, PD and Safety of CKD-381 and D026 in Healthy Subjects
Status: COMPLETED
Conditions: GERD
Interventions: DRUG: CKD-381|DRUG: D026
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Single Ascending Dose Study of BMS-791325 in HCV Infected Subjects
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: BMS-791325|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitalis Study - Observational Study on the Quality of Life in Patients Under Treatment for B-Chronic Lymphocytic Leukemia (B-CLL)
Status: COMPLETED
Conditions: Leukemia, B-Cell, Chronic
Interventions: DRUG: Alemtuzumab (MabCampath, BAY86-5045) and Fludarabine Phosphate (Fludara, BAY86-4864)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing the Efficacy of Topical Tazarotene Gel 0.1% v/s Microneedling in Atrophic Post Acne Scars
Status: COMPLETED
Conditions: Acne Scar
Interventions: DRUG: Tazarotene gel 0.1%|DEVICE: Microneedling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Oral Doses of BI 14332 CL as Tablet in Female and Male Patients With Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: BI 14332 CL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin/Etoposide/Radiotherapy +/- Consolidation Docetaxel in Advanced Stage III Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Cisplatin|DRUG: Etoposide|RADIATION: Radiation|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Verifying Remote Monitoring Effect on Net Cardiovascular Outcome; RemoteVerify (RêVe)
Status: RECRUITING
Conditions: Congestive Heart Failure|Defibrillators|Cardiac Resynchronization Therapy
Interventions: OTHER: remote monitoring only
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Cobalt-chromium Partial Dentures and Thermoplastic Partial Dentures
Status: UNKNOWN
Conditions: Jaw, Edentulous, Partially
Interventions: DEVICE: Thermoplastic partial denture|DEVICE: CoCr partial denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Mulligan on Sub-acromial Space in Patients With Shoulder Impingement Syndrome
Status: UNKNOWN
Conditions: Shoulder Impingement
Interventions: OTHER: mulligan technique|OTHER: conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oxygen Supplementation During Exercise in Chronic Obstructive Pulmonary Disease Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Hypoxia
Interventions: DRUG: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TSN1611 Treating Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation
Status: RECRUITING
Conditions: Malignant Neoplasm
Interventions: DRUG: TSN1611
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Virtual Reality Based Home Rehabilitation Program After Total Hip Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis, Hip
Interventions: PROCEDURE: virtual reality rehabilitation system (VRRS)|PROCEDURE: standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Apixaban Versus Dual-antiplatelet Therapy (Clopidogrel and Aspirin) in Acute Non-disabling Cerebrovascular Events
Status: UNKNOWN
Conditions: Ischemic Stroke|TIA
Interventions: DRUG: Apixaban|DRUG: Clopidogrel|DRUG: Aspirin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Computerized Cognitive Training in MS
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis|Cognitive Decline
Interventions: DEVICE: Computerized gaming rehabilitation Program 1|DEVICE: Computerized gaming rehabilitation Program 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antioxidant Supplementation in Patients With Kashin-Beck Disease
Status: UNKNOWN
Conditions: Kashin-Beck Disease
Interventions: DIETARY_SUPPLEMENT: Biological Antioxidant Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Different Neural Circuit Mechanisms Between Cognitive Therapy and Behavior Therapy for Patients With Panic Disorder: a Dynamic Research
Status: UNKNOWN
Conditions: Panic Disorder
Interventions: BEHAVIORAL: Cognitive therapy|BEHAVIORAL: Behavior therapy|DRUG: SSRI antidepressants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dupilumab Effects Against Aeroallergen Challenge
Status: RECRUITING
Conditions: Asthma, Allergic
Interventions: DRUG: Dupilumab|OTHER: House Dust Mites (HDM)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing TR Band to Statseal in Conjunction With TR Band
Status: COMPLETED
Conditions: Arterial Occlusion|Angina Pectoris|Cardiovascular Diseases|Atherosclerosis|Hematoma|Anticoagulant-Induced Bleeding|Coronary Artery Disease
Interventions: DEVICE: StatSeal|DEVICE: TR Band
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: AZD1305 Single and Multiple Ascending Dose Study in Healthy Japanese and Caucasian Subjects
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: AZD1305|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Passive Microwave Radiometry (MWR) and AI for COVID-19 Complications Early Diagnostics of Lungs
Status: COMPLETED
Conditions: Covid19
Interventions: DIAGNOSTIC_TEST: Passive Microwave Radiometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Standard Therapy With or Without Surgery and Mitomycin C in Treating Patients With Advanced Limited Peritoneal Dissemination of Colon Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: bevacizumab|BIOLOGICAL: cetuximab|DRUG: FOLFIRI regimen|DRUG: FOLFOX regimen|DRUG: capecitabine|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium|DRUG: mitomycin C|DRUG: oxaliplatin|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transradial and Transfemoral Coronary Angiography by EXPERienced operaTors
Status: COMPLETED
Conditions: Exposure to Ionizing Radiation|Coronary Heart Disease|Vascular Access Complication
Interventions: OTHER: Trans-radial|OTHER: Trans-femoral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Seasonal Influenza Vaccination Affect the Incidence of pH1N1 Influenza?
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluviral influenza vaccine, 2009-2010|BIOLOGICAL: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: the Effect of Carbetocin in Decreasing Intraoperative Blood Loss in Abdominal Myomectomy
Status: COMPLETED
Conditions: Abdominal Myomectomy
Interventions: DRUG: carbetocin 100 mcg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effect of JNJ-63623872 on Cardiac Repolarization Interval in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-63623872 2400 milligram (mg)|DRUG: JNJ-63623872 3000 mg|DRUG: JNJ-63623872|DRUG: Moxifloxacin|DRUG: Placebo (Matching with JNJ-63623872 2400 mg)|DRUG: Placebo (Matching with JNJ-63623872 3000 mg)|DRUG: Placebo (Matching with JNJ-63623872 Dose)|DRUG: Placebo (Matching with Moxifloxacin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Compare Two Strains of BCG
Status: COMPLETED
Conditions: Death, Infant|Morbidity;Infant
Interventions: BIOLOGICAL: BCG-Japan|BIOLOGICAL: BCG-Russia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Fluconazole in the Prevention of Fungal Infections in HIV-Infected Patients Living in Areas Where Fungal Infections Are Common
Status: COMPLETED
Conditions: Mycoses|HIV Infections|Coccidioidomycosis
Interventions: DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Is the AMH Intrafollicular Level a Predictor of the Ploidy Status of the Blastocyst?
Status: RECRUITING
Conditions: Infertility, Female|Infertility
Interventions: PROCEDURE: Oocyte Pick Up - Out of Study|PROCEDURE: Denudation - Out of Study|PROCEDURE: ICSI|PROCEDURE: Culture|GENETIC: Biopsy|PROCEDURE: Vitrification|PROCEDURE: OPU - Study Group|PROCEDURE: Denudation - Study Group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Epinephrine/ Phenylephrine for Preventing the Postreperfusion Syndrome During Reperfusion in Liver Transplantation
Status: COMPLETED
Conditions: Hypotension After Reperfusion in Liver Transplantation
Interventions: DRUG: phenylephrine|DRUG: epinephrine|DRUG: placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Amivantamab, Lazertinib, and Pemetrexed for First-line Treatment of Recurrent/Metastatic Non-small Cell Lung Cancers With Epidermal Growth Factor Receptor Mutations
Status: RECRUITING
Conditions: Metastatic Non-small Cell Lung Cancers
Interventions: DRUG: Amivantamab|DRUG: Lazertinib|DRUG: Pemetrexed 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplant From Matched Unrelated or Partially Matched Related Donors
Status: COMPLETED
Conditions: Blood Cancer|Blood and Marrow Transplant (BMT)
Interventions: PROCEDURE: ablative allogeneic hematopoietic cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quasi-experimental Study With a Control Group to Evaluate a Psychoeducational Intervention in Parkinson's Disease Patients and Carers
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: ReNACE Psychoeducational Intervention|OTHER: General Educational Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Maintenance Effect of Clobex Shampoo on Participants With Moderate to Severe Scalp Psoriasis
Status: COMPLETED
Conditions: Scalp Psoriasis
Interventions: DRUG: Clobex® Shampoo|DRUG: Clobex® Vehicle Shampoo|DRUG: Clobex® Shampoo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Using Divided Mesh and Using a Non Divided Mesh on Testicular Blood Flow and Volume in Laparoscopic Hernia Repair
Status: UNKNOWN
Conditions: Hernia, Inguinal
Interventions: PROCEDURE: Laparoscopic totally extraperitoneal procedure for inguinal hernia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imaging Biomarkers for Myofascial Pain
Status: ENROLLING_BY_INVITATION
Conditions: Myofascial Pain Syndrome|Healthy
Interventions: DIAGNOSTIC_TEST: Ultrasound imaging|DIAGNOSTIC_TEST: Bioimpedance spectroscopy|DIAGNOSTIC_TEST: Electromyography|DIAGNOSTIC_TEST: Physical examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PRediction of Early PostoperAtive Right vEntricular Failure in Mitral Valve Replacement/Repair Patients
Status: COMPLETED
Conditions: Right Heart Failure|Right Ventricular Dysfunction|Right Ventricular Failure|Mitral Valve Disease
Interventions: PROCEDURE: Mitral valve replacement/repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Acthar on Synovial Inflammation in Rheumatoid Arthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Acthar Injectable Product|DRUG: Depo medrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Micrografts From the Palatal Mucosa for Periodontal Regeneration
Status: RECRUITING
Conditions: Periodontitis
Interventions: DEVICE: Rigenera + bone substitute|DEVICE: Bone substitute alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics for Improving Post-surgical Healing
Status: RECRUITING
Conditions: Probiotics|Tooth, Impacted|Wound Heal|Gastrointestinal Complication
Interventions: PROCEDURE: Impacted tooth extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Intra-Operative Lymphatic Mapping in Patients With Invasive Carcinoma of the Cervix or Endometrial Carcinoma
Status: COMPLETED
Conditions: Cervical Cancer|Endometrial Cancer|Cervical Carcinoma
Interventions: OTHER: Lymphatic Mapping
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Early Incentive and Mobilization During COPD Exacerbation
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Hospital and home exercise training|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Nemtabrutinib (MK-1026) in China Participants With Relapsed or Refractory Hematologic Malignancies (MK-1026-005)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematological Malignancies
Interventions: DRUG: Nemtabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Trial to Evaluate the Efficacy and Safety of the Treatment With BPL-1 in Adult Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: BPL-1 Probiotic capsules|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention Evaluation WEH (Women Who Have Experienced Homelessness)
Status: NOT_YET_RECRUITING
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: NurseNET|OTHER: PAL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Probiotic Ayran on Gingivitis
Status: COMPLETED
Conditions: Gingivitis|Probiotics|Inflamed Gums
Interventions: DIETARY_SUPPLEMENT: probiotic ayran drink|DIETARY_SUPPLEMENT: Placebo ayran drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Usefulness of Echocardiography in Patients With Staphylococcus Aureus Bacteremia (ET-AUREUS Study).
Status: RECRUITING
Conditions: Staphylococcus Aureus Bacteremia|Infective Endocarditis
Interventions: DIAGNOSTIC_TEST: Echocardiography evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Octreotide VS Placebo in Prevention of Salivary Fistulae After Post Radiation Salvage Surgery
Status: UNKNOWN
Conditions: Fistula; Salivary Duct or Gland
Interventions: DRUG: octreotide|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Pharmacokinetics, Efficacy, Safety, Tolerability, of the Combination of Simeprevir (TMC435), Daclatasvir (BMS-790052), and Ribavirin (RBV) in Patients With Recurrent Chronic Hepatitis C Genotype 1b Infection After Orthotopic Liver Transplantation
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Simeprevir|DRUG: Daclatasvir|DRUG: Ribavirin|DRUG: Cyclosporine|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ixazomib as a Replacement for Carfilzomib and Bortezomib for Multiple Myeloma Patients
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Melphalan|DRUG: Prednisone|DRUG: Cyclophosphamide|DRUG: Dexamethasone|DIETARY_SUPPLEMENT: Ascorbic acid|DRUG: PLD|DRUG: Lenalidomide|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Preoperative Opioid-free Multimodal Analgesia on Time to Trial of Void in Ambulatory Urogynecologic Surgeries
Status: RECRUITING
Conditions: Pain, Postoperative|Postoperative Pain, Acute
Interventions: DRUG: Acetaminophen|DRUG: Celecoxib|DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Wool-derived Keratin Dressings for Venous Leg Ulcers
Status: COMPLETED
Conditions: Varicose Ulcer
Interventions: DEVICE: Keratin dressings|DEVICE: Usual care dressings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of PD-1 Inhibitor JTX-4014 Alone and in Combination With Vopratelimab in Biomarker-selected Subjects With Metastatic NSCLC After One Prior Platinum-containing Regimen
Status: TERMINATED
Conditions: NSCLC
Interventions: DRUG: Pimivalimab|DRUG: Vopratelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measuring Nutrition Literacy in Clinical Practice: Evaluating Effects Upon Providers and Patients
Status: COMPLETED
Conditions: Health Knowledge, Attitudes, Practice
Interventions: DIAGNOSTIC_TEST: Nutrition Literacy Assessment Instrument (NLit)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: DA Versus DAC as Postoperative Adjuvant Treatment for Early-stage Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel, Doxorubicin|DRUG: Docetaxel, Doxorubicin, Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety, Tolerability and Pharmacokinetics (PK) (Including Food Effect) of Oral Doses of AZD5847 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD5847|DRUG: Placebo to AZD5847
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination Chemotherapy in Treating Women With Stage II or Stage IIIA Breast Cancer That Has Spread to the Lymph Nodes
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: cyclophosphamide|DRUG: docetaxel|DRUG: doxorubicin hydrochloride|DRUG: paclitaxel|DRUG: tamoxifen citrate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of Etavopivat for the Treatment of Anemia in Patients With Myelodysplastic Syndromes (MDS)
Status: RECRUITING
Conditions: Very Low Risk, Low Risk, or Intermediate Risk MDS Per IPSS-R
Interventions: DRUG: Etavopivat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GAPVAC Phase I Trial in Newly Diagnosed Glioblastoma Patients
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: APVAC1 vaccine plus Poly-ICLC and GM-CSF|DRUG: APVAC2 vaccine plus Poly-ICLC and GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of Nintedanib (BIBF 1120) in Japanese Patients With Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Nintedanib high dose|DRUG: Nintedanib low dose|DRUG: Nintedanib medium dose|DRUG: Nintedanib medium dose|DRUG: Nintedanib high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improvement of Motor Imaginative Ability Through Functional Electrical Stimulation
Status: COMPLETED
Conditions: Electrode Site Reaction|Therapy, Directly Observed
Interventions: COMBINATION_PRODUCT: FESIA GRASP|COMBINATION_PRODUCT: VIRTUAL REHAB|COMBINATION_PRODUCT: GLOBUS ELITE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Home-based Exercise Training in Cardiac Patients
Status: COMPLETED
Conditions: Physical Fitness|Patient Adherence|Quality of Life|Autonomic Nervous System Imbalance
Interventions: BEHAVIORAL: Current guidelines rehabilitation|BEHAVIORAL: Mobile device guided rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Effects of Big Toe Flexor and Calf Strengthening Exercises on Medial Arch in Athletes With Flat Foot
Status: COMPLETED
Conditions: Sports Physical Therapy
Interventions: OTHER: Big Toe Flexor Strengthening Exercises|OTHER: Calf Strengthening Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Red Cell Distribution Width and Lactate Albumin Ratio as Prognostic Markers for Mortality in Sepsis and Septic Shock
Status: NOT_YET_RECRUITING
Conditions: Morality|Sepsis|Septic Shock
Interventions: DIAGNOSTIC_TEST: Red cell distribution width|DIAGNOSTIC_TEST: lactate albumin ratio measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of Octreotide Injection to Prevent GI Bleeding in Patients With Left Ventricular Assist Device (LVAD)
Status: COMPLETED
Conditions: Gastrointestinal Bleeding
Interventions: DRUG: Octreotide LAR Depot
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Synbiotic on the Gut Microbiota and Adiposity-related Markers in Healthy Overweight Subjects
Status: COMPLETED
Conditions: Gut Microbiota|Adiposity
Interventions: DIETARY_SUPPLEMENT: Synbiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Golimumab in Participants With Active Axial Spondyloarthritis (P07642, MK-8259-006)
Status: COMPLETED
Conditions: Spondylitis, Ankylosing
Interventions: BIOLOGICAL: Golimumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Pharmacodynamics Study of Oral Salmon Calcitonin in Healthy Postmenopausal Women
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Oral salmon calcitonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of PD-1 Inhibitors After CD30.CAR T Cell Therapy in Relapsed/Refractory Hodgkin Lymphoma
Status: RECRUITING
Conditions: Relapsed Hodgkin Lymphoma|Refractory Hodgkin Lymphoma
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Azacitidine to Evaluate Safety and Effectiveness for Chinese Patients With Higher Risk Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Myelodysplastic Syndrome (MDS)
Interventions: DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Older Subjects to Evaluate the Safety and Ability of Andexanet Alfa to Reverse the Anticoagulation Effect of Apixaban
Status: COMPLETED
Conditions: Bleeding
Interventions: BIOLOGICAL: Andexanet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary and Secondary Ventral Hernia Repair Using Long-term Resorbable Versus Non-resorbable Large Pore Synthetic Mesh.
Status: COMPLETED
Conditions: Primary and Secondary Ventral Hernia
Interventions: PROCEDURE: Placing the resorbable mesh|PROCEDURE: Non-resorbable synthetic mesh.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Of Ultrasound-Based Measures Of Inferior Vena Cava And Internal Jugular Vein For Prediction Of Hypotension During Induction Of General Anesthesia
Status: COMPLETED
Conditions: Ultrasound Based IVC IJV
Interventions: OTHER: Ultrasound-based measurements of IVC & IJV.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Escitalopram Trial for Irritable Bowel Syndrome (IBS) Patients With Panic Disorder
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Panic Disorder
Interventions: DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring Food Rejection Dispositions as Potential Risk Factors for Undernutrition in Hospitalized Children Aged 2 to 8
Status: RECRUITING
Conditions: Undernutrition
Interventions: OTHER: Children between 2 and 8 years, without medical treatments or pathologies impacting food intake and his parents
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety and Effective Study of Ginkgolides Diterpene Lactone Meglumine Injection in the Treatment of Ischemic Stroke.
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DRUG: Ginkgo diterpene lactone meglumine injection|DRUG: Ginkgo diterpene lactone meglumine injection simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sunitinib and Irradiated Donor Lymphocytes in Treating Patients With Metastatic Kidney Cancer
Status: TERMINATED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: sunitinib malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Postsurgical Analgesia With INL-001 in Abdominoplasty
Status: COMPLETED
Conditions: Pain, Postoperative|Abdominoplasty
Interventions: COMBINATION_PRODUCT: Bupivacaine Hydrochloride|COMBINATION_PRODUCT: Placebo collagen-matrix implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Mesenchymal Stem Cell Transplantation in Cirrhosis Patients With Refractory Ascites
Status: UNKNOWN
Conditions: Immune Function in Blood|Liver Function in Blood|Variation of Ascites|Characters of Quality of Life|Child-Pugh Score
Interventions: BIOLOGICAL: autologous bone marrow mesenchymal stem cells transplantation|BIOLOGICAL: autologous bone marrow msenchymal stem cells transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Valuation of the Safety and Efficacy of Combination of Cryoablation and Dendric Cell/Cytokine-induced Killers Cells Treatment for Advanced Liver Cancers
Status: NOT_YET_RECRUITING
Conditions: Advanced Liver Cancers
Interventions: BIOLOGICAL: DC-CIK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Safety & Immunogenicity of rLP2086 Vaccine in Adolescents
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: rLP2086|BIOLOGICAL: rLP2086|BIOLOGICAL: rLP2086|BIOLOGICAL: rLP2086
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Bevacizumab + mFOLFOX6 Versus Bevacizumab + FOLFIRI With Biomarker Stratification in Participants With Previously Untreated Metastatic Colorectal Cancer (mCRC)
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: 5-Fluorouracil|DRUG: Bevacizumab|DRUG: Irinotecan|DRUG: Leucovorin|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Investigating the Safety and Efficacy of BRC-003 in Refractory Post-Traumatic Epilepsy
Status: NOT_YET_RECRUITING
Conditions: Post-traumatic Epilepsy
Interventions: DRUG: PO BRC-003 (High Cannabidiol Cannabis Extract)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating GZ17-6.02 in Patients With Advanced Solid Tumors or in Combination With Capecitabine in Metastatic Hormone Receptor Positive Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Cancer|Gastric Cancer|Breast Cancer|Pancreatic Cancer|Prostate Cancer Metastatic|Colo-rectal Cancer|Solid Tumor|Solid Carcinoma|Solid Carcinoma of Stomach|Cancer of Stomach|Lymphoma|Sarcoma|Cutaneous T Cell Lymphoma|Head and Neck Squamous Cell Carcinoma|Basal Cell Carcinoma|Cutaneous T-cell Lymphoma|Cutaneous Squamous Cell Carcinoma
Interventions: DRUG: GZ17-6.02|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3374849 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3374849 - SC|DRUG: Insulin Degludec - SC|DRUG: LY3374849 - IV|DRUG: Insulin Degludec - IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Episodic Future Thinking to Improve Management of Type 2 Diabetes: Remote Delivery and Outcomes Assessment
Status: RECRUITING
Conditions: Type 2 Diabetes|Overweight and Obesity
Interventions: BEHAVIORAL: Episodic Future Thinking|BEHAVIORAL: Healthy Information Thinking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality vs Passive Distraction for Pain Management
Status: COMPLETED
Conditions: Virtual Reality|Pain|Pain Perception|Pain Management|Anxiety|Catastrophizing, Pain|Stress
Interventions: DEVICE: Passive Distraction|DEVICE: Virtual Reality Distraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed(DTcP)
Status: ACTIVE_NOT_RECRUITING
Conditions: Diphtheria, Tetanus and Acellular Pertussis
Interventions: BIOLOGICAL: Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed (DTcP)|BIOLOGICAL: Diphtheria，Tetanus and Acellular Pertussis Combined Vaccine，DTaP|BIOLOGICAL: Diphtheria,tetanus,pertussis(acellular,component),Inactivated polio vaccine(adsorbed）and Haemophilus influenzae type b conjugate vaccine,adsorbed,DTaP-IPV-Hib|BIOLOGICAL: DTcP|BIOLOGICAL: DTaP-IPV-Hib|BIOLOGICAL: DTcP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Laparoscopic Sleeve Gastrectomy With and Without Omentectomy
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: PROCEDURE: Laparoscopic restrictive procedure|PROCEDURE: Sleeve gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Belantamab Mafodotin in Patients With Relapsed or Refractory AL Amyloidosis
Status: RECRUITING
Conditions: AL Amyloidosis
Interventions: DRUG: Belantamab mafodotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Take a Break (TAB): mHealth-assisted Skills Building Challenge for Unmotivated Smokers
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Take a Break as an augmentation to NRT-sampling in Motivation Phase|BEHAVIORAL: NRT and mHealth assessment tool without feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise Training on Systemic Inflammation an Muscle Repair According to the Obstructive Chronic Pulmonary Disease (COPD) Phenotype
Status: UNKNOWN
Conditions: Obstructive Chronic Pulmonary Disease|Emphysema|Chronic Bronchitis
Interventions: OTHER: Combined Training (endurance and strength exercises)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Closed-Loop Insulin Delivery in Children Less Than 7 Years of Age
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: Closed-loop Insulin Pump therapy|DEVICE: Standard Insulin Pump Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral TXA on Buttock Bruising Post CCH Injections in Adult Females
Status: COMPLETED
Conditions: Cellulite
Interventions: DRUG: Collagenase Clostridium Histolyticum-Aaes|DRUG: Lysteda 650 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Single-Arm Study of Bempegaldesleukin (NKTR-214) Plus Nivolumab in Cisplatin Ineligible Patients Who Have Locally Advanced or Metastatic Urothelial Cancer
Status: COMPLETED
Conditions: Urinary Bladder Neoplasm|Neoplasm Metastasis
Interventions: BIOLOGICAL: Bempegaldesleukin|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mirvetuximab Soravtansine and Gemcitabine Hydrochloride in Treating Patients With FRalpha-Positive Recurrent Ovarian, Primary Peritoneal, Fallopian Tube, Endometrial, or Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Recurrent Breast Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Recurrent Uterine Corpus Carcinoma|Triple-Negative Breast Carcinoma
Interventions: DRUG: Gemcitabine|DRUG: Gemcitabine Hydrochloride|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Mirvetuximab Soravtansine|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VITAL - VITamins to Slow ALzheimer's Disease (Homocysteine Study)
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Folate|DRUG: Vitamin B6|DRUG: Vitamin B12
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Human Chorionic Gonadotropin (hCG) Priming Prior to Controlled Ovarian Hyperstimulation (COH) in Poor Responder In Vitro Fertilization (IVF) Patients
Status: COMPLETED
Conditions: Ovarian Response
Interventions: BIOLOGICAL: human chorionic gonadotropin|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 52 Week Open Label Trial of Memantine for Frontotemporal Lobar Degeneration
Status: COMPLETED
Conditions: Frontotemporal Lobar Degeneration
Interventions: DRUG: Memantine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: L. Reuteri ATCC PTA 5289 + L. Reuteri DSM 17938 in Pregnant Women
Status: UNKNOWN
Conditions: Periodontitis and Pregnancy
Interventions: DIETARY_SUPPLEMENT: Probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Low Analgesic Doses of Ketamine Associated With Opioids in Refractory Cancer Pain Treatment
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ketamine|DRUG: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Abdominal Massage Versus Visceral Manipulation on Constipation
Status: RECRUITING
Conditions: Constipation Chronic Idiopathic
Interventions: OTHER: abdominal massage|OTHER: visceral manipulation|OTHER: instructions on daily, dietary , toilet , and physical activity habits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Valproate and Memantine in the Prophylactic Management of Episodic Migraine.
Status: COMPLETED
Conditions: Migraine Headache
Interventions: DRUG: Valproate Sodium|DRUG: Memantine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Duloxetine Role in Reducing Opioid Consumption After Thoracotomy
Status: COMPLETED
Conditions: Post-thoracotomy Pain
Interventions: DRUG: Oral Duloxetine 60mg|DRUG: placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DHA For The Treatment of Pediatric Concussion Related to Sports Injury
Status: COMPLETED
Conditions: Concussion|Mild Traumatic Brain Injury
Interventions: DRUG: Docosahexaenoic acid (DHA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study in Participants With Early-Stage or Locally Advanced Human Epidermal Growth Factor Receptor (HER) 2-Positive Breast Cancer to Evaluate Treatment With Trastuzumab Plus (+) Pertuzumab + Docetaxel Compared With Trastuzumab + Placebo + Docetaxel
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: FEC Chemotherapy|PROCEDURE: Surgery|DRUG: Docetaxel|DRUG: Pertuzumab|DRUG: Placebo|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Sintilimab Combined With Anlotinib in Treatment of ED-SCLC
Status: UNKNOWN
Conditions: Small Cell Lung Cancer Extensive Stage
Interventions: DRUG: Sintilimab|DRUG: Anlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT