pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intra-Operative Corticosteroid Injection During Arthroscopic Shoulder Surgery
Status: TERMINATED
Conditions: Arthroscopic Shoulder Surgery|Intra-articular Debridement|Subacromial Decompression|Acromioplasty|Acromioclavicular Joint Resection
Interventions: DRUG: Methylprednisolone (40 mg depomedrol, 1ml, injection)|DRUG: Marcaine (4ml 0.5%, injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Intervention and Glycemic Improvement in Patients With Pre-diabetic Cystic Fibrosis.
Status: COMPLETED
Conditions: Cystic Fibrosis-related Diabetes|Cystic Fibrosis
Interventions: DIETARY_SUPPLEMENT: Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Telerehabilitation in Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Face to Face VRRS and telerehabilitation|BEHAVIORAL: Usual rehabilitation program|BEHAVIORAL: FTF VRRS plus unstructured CS|BEHAVIORAL: Face to Face VRRS plus active tDCS and telerehabilitation|BEHAVIORAL: Face to Face VRRS plus placebo tDCS and telerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determine the Frequency of a HTPPE in 5 Years (± on 1 Year) After a First Episode of Idiopathic Pulmonary Embolism.
Status: TERMINATED
Conditions: HTPPE|Idiopathic Pulmonary Embolism
Interventions: OTHER: HTPPE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Myofascial Techniques and Proprioceptive Neuromuscular Facilitation in Patients With Systemic Lupus Erythematosus.
Status: RECRUITING
Conditions: System; Lupus Erythematosus
Interventions: OTHER: Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of CG0070 Oncolytic Virus Regimen in Patients With High Grade Non-Muscle Invasive Bladder Cancer
Status: WITHDRAWN
Conditions: Bladder Cancer|High Grade|Non Muscle Invasive
Interventions: BIOLOGICAL: oncolytic adenovirus expressing GMCSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Cholecystitis - Early Laparoscopic Surgery Versus Antibiotic Therapy and Delayed Elective Cholecystectomy
Status: COMPLETED
Conditions: Acute Cholecystitis
Interventions: DRUG: moxifloxacin|PROCEDURE: cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy of Niraparib and Dostarlimab (TSR-042) in Recurrent/Metastatic HNSCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer
Interventions: DRUG: Niraparib|DRUG: Dostarlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Study for Evaluating the Safety and Efficacy of MASCT-I in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: BIOLOGICAL: MASCT-I|DRUG: Ifosfamide|DRUG: PD1 antibody|DRUG: Adriamycin|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Incision Laparoscopic Surgery (SILS) Versus Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Cholelithiasis|Biliary Dyskinesia
Interventions: PROCEDURE: SILS|PROCEDURE: Standard Laparoscopic Cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Time to Move in Pregnancy Hyperglycemia
Status: RECRUITING
Conditions: GDM|Physical Activity|Hyperglycemia|Glucose Intolerance|Circadian Rhythm|Exercise
Interventions: BEHAVIORAL: Moderate intensity walking or stepping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Clinical Trial Evaluating the Efficacy of Resultz Lice and Egg Elimination Kit on Pediatric and Adult Subjects
Status: COMPLETED
Conditions: Pediculus Capitis
Interventions: DEVICE: Apply Liquid Then Comb Out
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Processed Amniotic Fluid (PAF) Drops After Photorefractive Keratectomy (PRK)
Status: COMPLETED
Conditions: Photorefractive Keratectomy
Interventions: BIOLOGICAL: Amniotic Fluid (AFED)|OTHER: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Outcomes Among Urgent Care Clinic Patients With Inflammatory Bowel Disease
Status: UNKNOWN
Conditions: Inflammatory Bowel Disease|Ulcerative Colitis|Crohn Disease
Interventions: BEHAVIORAL: Telemedicine Follow-Up|OTHER: Telemedicine Monitoring|BEHAVIORAL: 30 Day Comprehensive Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Oral Health Related Quality of Life and Clinical Outcomes in Patients Undergoing Canine Disimpaction
Status: ACTIVE_NOT_RECRUITING
Conditions: Tooth, Impacted
Interventions: PROCEDURE: open exposure|PROCEDURE: closed exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventive Application of Letrozole Decrease Incidence of Early Onset of OHSS
Status: COMPLETED
Conditions: Ovarian Hyperstimulation Syndrome
Interventions: DRUG: letrozole|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Acceptability of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Fixed-Dose Combination (FDC) Tablets in Human Immunodeficiency Virus Type 1 (HIV-1) Infected Pediatric Participants, Using Matching Placebo Tablets
Status: COMPLETED
Conditions: HIV-1
Interventions: DRUG: D/C/F/TAF FDC placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Satisfaction, Confidence and Naturalness in Men With Psychogenic Erectile Dysfunction (ED)
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: BEHAVIORAL: Group Psychotherapy|OTHER: Group Psychotherapy plus Sildenafil citrate|DRUG: Sildenafil citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of Intermittent Hypoxia Treatment in Chronic Cerebral Hypoperfusion
Status: NOT_YET_RECRUITING
Conditions: Chronic Cerebral Hypoperfusion
Interventions: OTHER: Intermittent Hypoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Changes to Vulva, Vestibule, Urethral Meatus and Vagina 20 Weeks Post Daily Prasterone in Women With Dyspareunia
Status: COMPLETED
Conditions: Dyspareunia
Interventions: DRUG: Prasterone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: KTP vs CO2 Laser for the Treatment of Laryngeal Carcinoma
Status: UNKNOWN
Conditions: Laryngeal Neoplasms
Interventions: DEVICE: CO2 laser|DEVICE: KTP laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Selinexor Plus Gemcitabine in Selected Advanced Soft-tissue Sarcoma (SeliSarc)
Status: RECRUITING
Conditions: Sarcoma,Soft Tissue
Interventions: DRUG: Selinexor 20 MG|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of JUVÉDERM® VOLBELLA® With Lidocaine for Lip Enhancement in Chinese Adults
Status: COMPLETED
Conditions: Lip Enhancement
Interventions: DEVICE: JUVÉDERM® VOLBELLA® XC with Lidocaine|OTHER: No-treatment Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Responsiveness of Exercise Tests in Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Sildenafil|DRUG: Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Total Intravenous Anesthesia vs. Inhalational Anesthesia in Acute Subdural Hematoma Patients
Status: COMPLETED
Conditions: Acute Subdural Hematoma
Interventions: DRUG: Propofol|DRUG: Isoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Two Combination Chemotherapy Regimens in Treating Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: cisplatin|DRUG: gemcitabine hydrochloride|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Allogeneic Mesenchymal Precursor Cells (Rexlemestrocel-L) for the Treatment of Heart Failure.
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: BIOLOGICAL: Allogeneic Mesenchymal Precursor Cells (MPCs)|OTHER: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics of VI-0521 Subjects With Renal Impairment
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: Topirmate and Phentermine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Determine the Maximum Tolerated Dose and to Assess the Safety and Pharmacokinetic Profile of Oral Paclitaxel in Patients With Advanced Solid Cancer
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: Paclitaxel+HM30181
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative ChemoRadiation And FOLFOXIRI for Rectal Cancer (CRAFTER) for Rectal Cancer
Status: RECRUITING
Conditions: Cancer of Rectum
Interventions: DRUG: combination of drugs (chemoradiation (capecitabine and radiation) + FOLFOXIRI (Oxaliplatin, leucovorin, irinotecan, and fluorouracil)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Finding Study of Intranasal Midazolam for Procedural Sedation in Children
Status: COMPLETED
Conditions: Procedural Anxiety
Interventions: DRUG: Intranasal midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Music Breathing for Caregivers of Children Newly Diagnosed With Cancer
Status: RECRUITING
Conditions: Oncology|Psychological Distress
Interventions: BEHAVIORAL: mHealth-delivered music breathing therapy|BEHAVIORAL: Online educational modules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Busulfan, Melphalan, and Stem Cell Transplant After Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma
Status: COMPLETED
Conditions: Ganglioneuroblastoma|Stage 1 Neuroblastoma|Stage 2 Neuroblastoma|Stage 2A Neuroblastoma|Stage 2B Neuroblastoma|Stage 3 Neuroblastoma|Stage 4 Neuroblastoma|Stage 4S Neuroblastoma
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Busulfan|DRUG: Cisplatin|DRUG: Cyclophosphamide|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide|RADIATION: External Beam Radiation Therapy|BIOLOGICAL: Filgrastim|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan|DRUG: Mesna|PROCEDURE: Peripheral Blood Stem Cell Transplantation|OTHER: Pharmacological Study|DRUG: Topotecan Hydrochloride|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Clips Versus Overstich Suturing System Device for Closure of Mucosotomy After G-POEM
Status: COMPLETED
Conditions: Gastroparesis
Interventions: PROCEDURE: Closure of mucosotomy using endoscopic clips|PROCEDURE: Closure of mucosotomy using OverStitch™ suturing device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PTH And Calcium Responses to Exercise in Older Adults Experiment 2 (PACE Sr. 2)
Status: RECRUITING
Conditions: Osteoporosis
Interventions: DRUG: Calcium Chloride/Calcium Gluconate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CD24Fc for the Treatment of Immune Related Adverse Events in Patients With Advanced Solid Tumors, TIRAEC Study
Status: TERMINATED
Conditions: Advanced Malignant Solid Neoplasm
Interventions: BIOLOGICAL: CD24 Extracellular Domain-IgG1 Fc Domain Recombinant Fusion Protein CD24Fc|DRUG: Placebo Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesia With Buprenorphine for Postoperative Pain Control and Quality of Life After Spinal Surgery
Status: COMPLETED
Conditions: Spinal Stenosis|Pain, Postoperative
Interventions: DRUG: Buprenorphine|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reference Values for Plasma Catechols
Status: COMPLETED
Conditions: Healthy Volunteers|Normal Physiology
Interventions: OTHER: Coffee|OTHER: Banana|OTHER: Olives|OTHER: Temp. manip.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lentiviral-mediated Gene Therapy of Fanconi Anemia Patients Subtype A
Status: COMPLETED
Conditions: Fanconi Anemia
Interventions: PROCEDURE: IV administration of Genetically Engineered Hematopoietic Stem/Progenitors Cells (HSPCs)|BIOLOGICAL: Genetically Engineered Hematopoietic Stem/Progenitor Cells|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Filgrastim|DRUG: Plerixafor|PROCEDURE: Bone Marrow Aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Avelumab in Metastatic Gastronetro-pancreatic （GEP） Neuroendocrine Carcinoma （NEC, WHO Grade 3） as Second-line Treatment After Failing to Etoposide+Cisplatin: Integration of Genomic Analysis to Identify Predictive Molecular Subtypes
Status: COMPLETED
Conditions: Neuroendocrine Carcinoma, Grade 3
Interventions: DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Noninvasive Blood Vessel Functionality Parameters and Cerebral Hemodynamics in Neurocritical Care Patients
Status: RECRUITING
Conditions: Brain Injuries|Intracranial Pressure Increase|Monitoring
Interventions: DEVICE: Intracranial Pressure Noninvasive Monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Salivary Flow Promoted by Sugar-Free Chewing Gum
Status: COMPLETED
Conditions: Saliva Altered
Interventions: BEHAVIORAL: Mastication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hysteroscopic Isthmocele Repair on IVF Outcome
Status: RECRUITING
Conditions: Reproductive Issues|Cesarean Section; Dehiscence|Intrauterine Disorder
Interventions: PROCEDURE: Hysteroscopic CS scar defect repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Two Modern Hydroxyethyl Starch Solutions in Major Urological Procedures
Status: UNKNOWN
Conditions: Urologic Surgical Procedures
Interventions: DRUG: 6% HES 130/0.4 in NaCl 0.9% (Voluven, Fresenius Kabi, Bad Hom-bourg, Germany)|DRUG: Tetraspan, B. Braun, Melsungen, Germany
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Reducing COVID-19 Related Disability in Rural Community-Dwelling Older Adults Using Smart Technology
Status: ACTIVE_NOT_RECRUITING
Conditions: Quality of Life|Disabilities Multiple
Interventions: BEHAVIORAL: Standard Health Education|BEHAVIORAL: Self Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Electrical and Acoustic Stimulation for Tinnitus
Status: RECRUITING
Conditions: Tinnitus|Tinnitus, Subjective
Interventions: OTHER: transcranial Random Noise Stimulation (tRNS) with acoustic stimulation (AS)|OTHER: transcranial Random Noise Stimulation (tRNS) without acoustic stimulation (AS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Eravacycline Compared With Meropenem in Complicated Intra-abdominal Infections
Status: COMPLETED
Conditions: Complicated Intra-abdominal Infections|Complicated Appendicitis
Interventions: DRUG: Eravacycline|DRUG: Meropenem|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Childrens Preparation Before MRI on Anxiety and Need for Anesthesia: a Prospective Randomized Clinical Trial
Status: COMPLETED
Conditions: Proportion of Anesthesia|Anxiety Level
Interventions: BEHAVIORAL: Full interactive instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analysis of the Role of Hepatocyte SLAMF3 Receptor and Drug Resistance Proteins (MDR) in Resistance to Treatment With Sorafenib in CHC Patients
Status: WITHDRAWN
Conditions: Hepatocyte Receptor|Hepatocellular Carcinoma
Interventions: OTHER: Study on samples of tumor and peri-tumor tissues from patients with hepatocellular carcinoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of 1440nm Laser vs. Botulinum Toxin or miraDry® Microwave For Treatment of Axillary Hyperhidrosis
Status: COMPLETED
Conditions: Hyperhidrosis
Interventions: DEVICE: miraDry|DEVICE: Nd:YAG Laser|DEVICE: Botox®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Two Mobilization Techniques of Ankle on Balance in Patients With Chronic Ankle Instability
Status: UNKNOWN
Conditions: Ankle Sprains
Interventions: OTHER: Experimental MWM|OTHER: Experimental Thrust|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dysphagia Rehabilitation for Nasopharyngeal Carcinoma Patients Post Radiotherapy
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma|Radiotherapy
Interventions: BEHAVIORAL: Traditional rehabilitation (TR)|BEHAVIORAL: Transcutaneous electrical stimulation (ES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of A Quadrivalent Influenza Vaccine
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Quadrivalent influenza vaccine|BIOLOGICAL: Trivalent influenza vaccine A|BIOLOGICAL: Trivalent influenza vaccine B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacogenomics Applied to Chronic Pain Treatment in Primary Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain
Interventions: GENETIC: Pharmacogenetic Testing|OTHER: Pharmacist Consultation Note|OTHER: Delayed pharmacogenetic testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Vitamin D Deficiency
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D drops, 200 or 400 or 600 IU/day or 800 IU/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Randomized Double Blinding Controlled Study on" Jia Wei Xiao Yao Jiaonang" Treating Mild to Moderate Major Depressive Disorder
Status: UNKNOWN
Conditions: Depressive Disorder
Interventions: DRUG: Sertraline plus placebo of JWXYJN|DRUG: JWXYJN plus placebo of Sertraline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Thoracic Mobilization in Individuals With Subacromial Pain Syndrome
Status: COMPLETED
Conditions: Subacromial Pain Syndrome
Interventions: OTHER: Exercise Group|OTHER: Thoracic Mobilization Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safe and Timely Antithrombotic Removal - Direct Oral Anticoagulants Apixaban & Rivaroxaban (STAR-D)
Status: TERMINATED
Conditions: Hemorrhage, Surgical|Hemorrhage Postoperative|Blood Loss, Surgical|Blood Loss, Postoperative
Interventions: DEVICE: Sham comparator|DEVICE: DrugSorb-ATR system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma
Status: RECRUITING
Conditions: Plasmablastic Lymphoma|Ann Arbor Stage I Diffuse Large B-Cell Lymphoma|Ann Arbor Stage II Diffuse Large B-Cell Lymphoma|Ann Arbor Stage III Diffuse Large B-Cell Lymphoma|Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Cyclophosphamide|BIOLOGICAL: Daratumumab|DRUG: Doxorubicin|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide|DRUG: Prednisone|DRUG: Vincristine|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Metacarpophalangeal Joint Blocking Splint With Relative Motion Extension Splint for Trigger Finger
Status: ENROLLING_BY_INVITATION
Conditions: Trigger Finger
Interventions: OTHER: Splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Activase (Ateplase) vs Placebo in Complicated Pleural Effusions (CPE)/Empyemas
Status: COMPLETED
Conditions: Pleural Effusion Associated With Pulmonary Infection|Bacterial Pleural Effusion Other Than Tuberculosis
Interventions: DRUG: Alteplase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementing a School Prevention Program to Reduce Injuries Through Neuromuscular Training
Status: UNKNOWN
Conditions: Wounds and Injuries|Adolescent|Athletic Injuries|Sport Injury|Sports Injuries in Children
Interventions: OTHER: Neuromuscular training program|OTHER: Standard-of-practice Warm-up (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Notch Inhibitor in Advanced Cancer
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: LY900009 - Dose Escalation Phase (Part A)|DRUG: LY900009 - Dose Confirmation Phase (Part B)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplant for Inborn Errors of Metabolism
Status: COMPLETED
Conditions: Adrenoleukodystrophy|Metachromatic Leukodystrophy|Globoid Cell Leukodystrophy|Gaucher's Disease|Fucosidosis|Wolman Disease|Niemann-Pick Disease|Batten Disease|GM1 Gangliosidosis|Tay Sachs Disease|Sandhoff Disease
Interventions: PROCEDURE: Stem Cell Transplant|DRUG: Busulfan, Cyclophosphamide, Antithymocyte Globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Topical Ranpirnase to Treat Genital Warts (HPV)
Status: COMPLETED
Conditions: Condylomata Acuminata|Papillomavirus Infections|Sexually Transmitted Diseases
Interventions: DRUG: Ranpirnase|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HERTHENA-Lung01: Patritumab Deruxtecan in Subjects With Metastatic or Locally Advanced EGFR-mutated Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer Metastatic|Non-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor
Interventions: DRUG: Patritumab Deruxtecan (Fixed dose)|DRUG: Patritumab Deruxtecan (Up-Titration)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib and Ganciclovir in Treating Patients With Relapsed or Refractory Epstein Barr Virus-Positive Lymphoma
Status: TERMINATED
Conditions: Lymphoma|Lymphoproliferative Disorder
Interventions: DRUG: bortezomib + ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of PRO-118 Ophthalmic Solution in Allergic Conjunctivitis
Status: WITHDRAWN
Conditions: Ocular Itching|Ocular Allergy|Seasonal Allergic Conjunctivitis|Perennial Allergic Conjunctivitis|Conjunctivitis, Allergic
Interventions: DRUG: PRO-118 Ophthalmic Solution 0.015%|DRUG: PRO-118 Ophthalmic Solution 0.015 %|DRUG: PRO-118 Ophthalmic Solution 0.020 %|DRUG: PRO-118 Ophthalmic Solution 0.020 %|DRUG: Placebo Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does An Abnormal PFA 100 Predict Bleeding After Renal Biopsy?
Status: TERMINATED
Conditions: Kidney Failure, Acute|Kidney Failure, Chronic|Blood Platelet Disorders|Hemorrhage
Interventions: DEVICE: measuring Platelet Function Analyser-100 (PFA-100) platelet function before kidney biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Safety and Tolerability Study of GSK2982772, in Single (in Both Fed and Fasted States) and Repeat Oral Doses in Healthy Male Subjects
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases
Interventions: DRUG: GSK2982772 solution|DRUG: GSK2982772 capsule|DRUG: Placebo solution|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Immunogenicity of the Venezuelan Equine Encephalitis (VEE) Attenuated Live-Virus Vaccine
Status: WITHDRAWN
Conditions: Venezuelan Equine Encephalitis
Interventions: BIOLOGICAL: VEE 3526
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Comparing Safety and Efficacy of BOL-303259-X With Timolol Maleate in Subjects With Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: BOL-303259-X|DRUG: Timolol|DRUG: BOL-303259-X
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of Lactobacillus Salivarius AP-32 and Bifidobacterium Animalis Subsp. Lactis CP-9 in Healthy Infants.
Status: COMPLETED
Conditions: Safety Issues
Interventions: OTHER: Lactobacillus salivarius AP-32|OTHER: Bifidobacterium animalis subsp. lactis CP-9|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: In Clinic Optometrist Insertion of Dextenza Prior to Cataract Surgery
Status: NOT_YET_RECRUITING
Conditions: Cataract
Interventions: DRUG: Dextenza 0.4Mg Ophthalmic Insert|DRUG: Topical Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Pharmacodynamics/Pharmacokinetics and Safety of LY03003 in Early PD Patients
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: LY03003|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Combination of APG-1252 (Pelcitoclax) and Cobimetinib in Recurrent Ovarian and Endometrial Cancers
Status: RECRUITING
Conditions: Advanced Endometrial Carcinoma|Metastatic Endometrial Carcinoma|Metastatic Fallopian Tube Carcinoma|Metastatic Platinum-Resistant Ovarian Carcinoma|Metastatic Primary Peritoneal Carcinoma|Recurrent Endometrial Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Platinum-Resistant Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Stage III Uterine Corpus Cancer AJCC v8|Stage IV Uterine Corpus Cancer AJCC v8
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Cobimetinib|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Multigated Acquisition Scan|DRUG: Pelcitoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Investigating the Pharmacokinetic Interaction Between INX-08189 and Verapamil HCL ER in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: INX-08189 50 mg|DRUG: 240 mg verapamil HCL ER|DRUG: 50 mg dose of INX-08189 and 240 mg verapamil HCL ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Does ALlopurinol Regress lefT Ventricular Hypertrophy in End Stage REnal Disease: The ALTERED Study
Status: COMPLETED
Conditions: End Stage Renal Disease|Left Ventricular Hypertrophy
Interventions: DRUG: Allopurinol|DRUG: Placebo (for allopurinol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Safety and Efficacy of Enhanced PSMA CAR- T in Refractory CRPC
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer|Castration-resistant Prostate Cancer
Interventions: DRUG: Enhanced autologous PSMA-CAR T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Phase 3 Study of Long-acting hGH (MOD-4023) in Growth Hormone Deficient Children
Status: COMPLETED
Conditions: Pediatric Growth Hormone Deficiency
Interventions: DRUG: MOD-4023|DRUG: Somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Study to Evaluate the Safety and Effectiveness of the Spirair Implant
Status: RECRUITING
Conditions: Nasal Septal Deviation|Nasal Airway Obstruction
Interventions: DEVICE: Implantation of Spirair Nasal Device using the Spirair delivery system.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Safinamide on Parkinson's Disease Related Chronic Pain
Status: COMPLETED
Conditions: Idiopathic Parkinson Disease
Interventions: DRUG: Safinamide Methanesulfonate|OTHER: Safinamide methanesulfonate matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan, Cisplatin, and Bevacizumab in Treating Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
Status: COMPLETED
Conditions: Adenocarcinoma of the Gastroesophageal Junction|Diffuse Adenocarcinoma of the Stomach|Intestinal Adenocarcinoma of the Stomach|Mixed Adenocarcinoma of the Stomach|Recurrent Gastric Cancer|Stage IIIA Gastric Cancer|Stage IIIB Gastric Cancer|Stage IIIC Gastric Cancer|Stage IV Gastric Cancer
Interventions: DRUG: irinotecan hydrochloride|BIOLOGICAL: bevacizumab|DRUG: cisplatin|PROCEDURE: computed tomography|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Application and Evaluation of eHealth Literacy (eHL) Concept
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Chronic Kidney Diseases|Cardiovascular Diseases
Interventions: BEHAVIORAL: experience learning programs of eHealth care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Investigating the Effect of At Home Thermal Therapy on Dry Eye Patients With Meibomian Gland Dysfunction
Status: UNKNOWN
Conditions: Meibomian Gland Dysfunction|Dry Eye Disease
Interventions: DEVICE: Thermal therapy device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmeditomedine as an Adjuvant to Levobupivacaine in Transversus Thoracis Plane Block on the Management of Post-sternotomy Pain in Open-heart Surgeries
Status: NOT_YET_RECRUITING
Conditions: Pain, Postoperative
Interventions: PROCEDURE: transversus thoracis plane block|DRUG: Dexmedetomidine|DRUG: Levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Gastrointestinal Tolerability Study Of Dimethyl Fumarate In Participants With Relapsing-Remitting Multiple Sclerosis In Germany
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: dimethyl fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of KH903 in Patients With Advanced Gastric or Gastroesophageal Junction Adenocarcinoma As Second-Line Therapy
Status: UNKNOWN
Conditions: Gastric Cancer|Gastroesophageal Cancer
Interventions: DRUG: KH903 + Paclitaxel|DRUG: Placebo + Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical Trial of Recombinant COVID-19 Variant Vaccine (Sf9 Cell) (WSK-V102)
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: Recombinant COVID-19 variant vaccine(Sf9 cell)|BIOLOGICAL: Recombinant COVID-19 vaccine(CHO cell)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: First-In-Human Study of ChAdOx1-HBV & MVA-HBV Vaccines (VTP-300) for Chronic HBV
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: ChAdOx1-HBV|BIOLOGICAL: MVA-HBV|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Omalizumab for Treatment of Chronic Rhinosinusitis With Nasal Polyposis
Status: COMPLETED
Conditions: Chronic Rhinosinusitis|Nasal Polyps
Interventions: DRUG: Xolair placebo|DRUG: Xolair (omalizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COMPARISON BETWEEN TWO SUB-TYPES OF HIGH INTENSITY INTERVAL TRAINING
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: OTHER: The high-volume HIIT|OTHER: The low-volume HIIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carfilzomib, Lenalidomide, and Dexamethasone Versus Bortezomib, Lenalidomide and Dexamethasone (KRd vs. VRd) in Patients With Newly Diagnosed Multiple Myeloma (COBRA)
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Non-invasive Ablation of Ventricular Tachycardia
Status: WITHDRAWN
Conditions: Ventricular Tachycardia
Interventions: PROCEDURE: 4-D navigated stereotactic radio surgical ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Assess Body Fluid Homeostasis After Administration of ACT-132577 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Aprocitentan|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Exploratory Observation of Two Short-term Regimens After LAA Occlusion by LAMax LAAC® Device for Subjects With Non-valvular Atrial Fibrillation
Status: RECRUITING
Conditions: Non-valvular Atrial Fibrillation
Interventions: DRUG: Dual antiplatelet|DRUG: Novel oral anticoagulant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Priming Immunotherapy in Advanced Disease With Radiation
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer|Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Immune checkpoint inhibitor|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of YM155 Plus Docetaxel as First-Line Treatment in Subjects With HER2 Negative Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: YM155|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of the DASH vs. the Mediterranean Diet Combined With Salt Restriction on Blood Pressure Levels in Adults
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Salt Restriction Group (SRG)|BEHAVIORAL: DASH Diet combined with salt restriction Group (DDG)|BEHAVIORAL: Mediterranean Diet combined with salt restriction Group (MDG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Role of Allo-HSCT in MRD-negative Patients With AML Under the Age of 60 Years in the First Complete Remission
Status: RECRUITING
Conditions: AML
Interventions: PROCEDURE: allo-HSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Immunogenicity of Fluarix™ 2006/2007 in Adults Aged 18 Years or Above
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluarix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: How is Aerobic Exercise Compared to Localized Pain Relief Exercises in Patients With Jaw Pain and Neck Pain?
Status: RECRUITING
Conditions: Temporomandibular Disorder|Neck Pain
Interventions: OTHER: Aerobic exercise|OTHER: Neck motor control exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Blood Stem Cell Transplantation From Family Haploidentical Donors in Patients With Myelodysplastic Syndrome and Acute Leukemia Under Primary Prophylaxis With Posaconazole
Status: COMPLETED
Conditions: Transplant-Related Hematologic Malignancy|Leukemia, Acute|Myelodysplastic Syndromes|Graft Vs Host Disease|Fungal Infection
Interventions: DRUG: Conditioning treatment "Thiotepa-Treosulfan-Fludarabine"|PROCEDURE: PBSC graft|DRUG: GvHD prophylaxis|DRUG: Primary antifungal prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Post-surgical Antibiotic Therapy in Spine Infections - a Prospective, Randomized, Unblinded, Non-inferiority Trial
Status: RECRUITING
Conditions: Infection
Interventions: DRUG: duration of standard antibiotic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sickness Absence Versus Physical, Mental, and Job-related Factors in Patients With Chronic Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Asthma
Interventions: OTHER: Vocational pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Phase I Study to Assess Novel Cream in a Psoriasis Plaque Test
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: AN2728 Cream, 2%|DRUG: AN2728 Cream, 1%|DRUG: AN2728 Cream, 0.3%|DRUG: AN2728 Cream Vehicle|DRUG: Betnesol®-V Creme, 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect and Efficacy of Xpedition™/Alpine™, Everolimus-eluting Stent for Coronary Atherosclerosis
Status: UNKNOWN
Conditions: Coronary Artery Disease|Percutaneous Coronary Intervention|Acute Coronary Syndrome|Angina Pectoris
Interventions: DEVICE: Alpine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Learn How Different Preparations of Osivelotor Taste and Enter the Blood With Food or Liquids or With an Antacid in Healthy Adults.
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: Osivelotor|OTHER: Famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 723/726 Proof of Concept Study in Allergen Challenge Chamber in Hannover
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: DRUG: GSK835726 10mg|DRUG: GSK1004723 1000mcg|DRUG: Cetirizine 10mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LiST Plus PRP Injection Therapy vs LiST Monotherapy for ED Treatment
Status: UNKNOWN
Conditions: Erectile Dysfunction
Interventions: COMBINATION_PRODUCT: LiST + PRP intracorporeal injection|COMBINATION_PRODUCT: LiST + Placebo(normal saline intracorporeal injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cerclage After Full Dilatation Caesarean Section
Status: UNKNOWN
Conditions: Preterm Birth|Preterm Premature Rupture of Membrane|Preterm Spontaneous Labor With Preterm Delivery
Interventions: PROCEDURE: Insertion of transvaginal cerclage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer
Status: RECRUITING
Conditions: Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia|Endometrial Carcinoma
Interventions: PROCEDURE: Biopsy|DRUG: Extended Release Metformin Hydrochloride|DRUG: Megestrol Acetate|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION