pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Reaching for Evidence-baSed Chemotherapy Use in Endocrine Sensitive Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Invasive Breast Cancer|Estrogen Receptor Positive Tumor|Human Epidermal Growth Factor Receptor 2 Negative Tumor
Interventions: OTHER: Observation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER
Status: RECRUITING
Conditions: Endometrial Cancer
Interventions: RADIATION: Vaginal brachytherapy|RADIATION: Adjuvant radiotherapy (EBRT +/- brachytherapy)|OTHER: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Single Dose Study of JZP-386 to Evaluate Safety, Pharmacokinetics and Pharmacodynamics
Status: COMPLETED
Conditions: Narcolepsy, Excessive Daytime Sleepiness
Interventions: DRUG: Placebo|DRUG: Sodium Oxybate|DRUG: JZP-386
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomised, Double-blind, Placebo Controlled Study With Oralgen Grass Pollen Rhinoconjunctivitis
Status: UNKNOWN
Conditions: Allergic Rhinoconjunctivitis
Interventions: DRUG: Oralgen|OTHER: placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Outcome Evaluation for Burn Scar Therapy-laser and Surgery in Patients in Formosa Fun Coast Explosion
Status: COMPLETED
Conditions: Patients With Major Burn Injury in Formosa FunCost Explosion
Interventions: PROCEDURE: Laser and Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Pegylated Interferon Alfa-2b and Ribavirin After Orthotopic Liver Transplantation in Subjects With Chronic Hepatitis C Recurrence (P04590AM3)(COMPLETED)
Status: COMPLETED
Conditions: Liver Transplantation|Hepatitis C, Chronic|Liver Cirrhosis
Interventions: DRUG: Combination of (a) pegylated interferon alfa-2b and (b) rebetol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Cardiopulmonary Function in Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Muscular Dystrophy, Duchenne
Interventions: OTHER: Magnetic Resonance Imaging (MRI)|OTHER: Pulmonary Function Testing (PFT)|OTHER: Metabolic Exercise Testing using stationary bicycle|OTHER: Echocardiogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of the Influence of Careless™, a Mangifera Indica Fruit Powder, on Microcirculation and Endothelial Function
Status: COMPLETED
Conditions: Microcirculation|Metabolism|Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Mango fruit powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improving Insulin Sensitivity by Non-invasive Brain Stimulation in Persons With Insulin Resistance
Status: UNKNOWN
Conditions: Insulin Resistance|Transcranial Direct Current Stimulation
Interventions: DEVICE: anodal transcranial direct current stimulation|DEVICE: cathodal transcranial direct current stimulation|DEVICE: transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ADVANCE MPI 1: Study of Regadenoson Versus Adenoscan® in Patients Undergoing Myocardial Perfusion Imaging (MPI)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Regadenoson|DRUG: Adenosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Combinations of Performance-enhancing Supplements on Exercise Performance
Status: UNKNOWN
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Sodium bicarbonate and caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prinomastat and Combination Chemotherapy in Treating Patients With Metastatic or Recurrent Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: gemcitabine hydrochloride|DRUG: prinomastat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Clips Versus Omentopexy on Postoperative Bleeding
Status: COMPLETED
Conditions: Bleeding|Postoperative Complications|Postoperative Nausea and Vomiting
Interventions: PROCEDURE: Omentopexy with Laparoscopic Sleeve Gastrectomy|PROCEDURE: Clips with Laparoscopic Sleeve Gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Iguratimod Plus Methotrexate Compared to Leflunomid Plus Methotrexate in Patients With Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Iguratimod|DRUG: Leflunomide|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin E in Preventing the Side Effects of Isotretinoin in Former and Current Smokers Who Are Receiving Isotretinoin to Prevent Lung Cancer
Status: WITHDRAWN
Conditions: Lung Cancer
Interventions: DIETARY_SUPPLEMENT: Vitamin E (AT)|DRUG: Isotretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Minocycline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medico-economic Evaluation of ENTERRA Therapy
Status: COMPLETED
Conditions: Gastroparesis|Vomiting|Nausea
Interventions: DEVICE: Implantation of ENTERRA therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Stretching Techniques in Patients Suffering From Subacromial Syndrome
Status: UNKNOWN
Conditions: Subacromial Impingement Syndrome
Interventions: PROCEDURE: Long Lever Group|PROCEDURE: Short Lever Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proprioceptive Stimulation With Manual Bilateral Rhythmic Exercise in Post-stroke Patients
Status: TERMINATED
Conditions: Stroke|Hemiparesis
Interventions: OTHER: Proprioceptive based training (PBT)|OTHER: Conventional neuromotor treatment (CNT).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paravertebral Block to Reduce the Incidence of New Onset Atrial Fibrillation After Cardiac Surgery
Status: RECRUITING
Conditions: New Onset Atrial Fibrillation|Anesthesia, Local|Cardiac Disease
Interventions: DRUG: Ropivacaine 0.2% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Effects of Standardized Chokeberry Extracts With Various Formulations on the Levels of Selected Markers Associated With Cardiovascular Disease
Status: COMPLETED
Conditions: Hypertension|Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Complex product|DIETARY_SUPPLEMENT: Chokeberry extract in liposomal formulation|DIETARY_SUPPLEMENT: Chokeberry extract in traditional formulation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Maternal Well-Being Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Postpartum Depression|Postpartum Anxiety|Weight Retention, Postpartum|Nutritional and Metabolic Diseases
Interventions: OTHER: Meals|OTHER: Meals + Social Support|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Open-Label Study Of CP-690,550 As Long-Term Therapy (48 Weeks) In Subjects With Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: CP-690,550|DRUG: CP-690,550
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Detection of Familial Hypercholesterolemia in Children
Status: RECRUITING
Conditions: Familial Hypercholesterolemia|Familial Hypercholesterolemia - Heterozygous|Familial Hypercholesterolemia - Homozygous
Interventions: OTHER: lifestyle assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Docetaxel or Pemetrexed With or Without Cetuximab in Patients With Recurrent or Progressive Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Pemetrexed|BIOLOGICAL: Cetuximab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurocognitive and Neurobiological Improvement in ADHD Children With High Protein Diet
Status: COMPLETED
Conditions: ADD|ADHD
Interventions: DRUG: BP22042013|DIETARY_SUPPLEMENT: Low carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Influence of Daily Honey Consumption on IR in Obese Women With IR
Status: RECRUITING
Conditions: Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Honey|DIETARY_SUPPLEMENT: Other carbohydrate alternatives such as jell-o
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Change of Overactive Bladder Symptoms in Women Post Pubovaginal Sling Procedure for Stress Incontinence
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DEVICE: Pubovaginal sling procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Eculizumab in Paroxysmal Nocturnal Hemoglobinuria Patients
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: BIOLOGICAL: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cervical Preparation for Surgical Abortion at 12-14 Weeks: a Prospective, Randomized, Evaluator-blinded, Multicenter, Controlled Comparison Between Mifepristone, Misoprostol and Their Combination
Status: UNKNOWN
Conditions: Surgical Abortion
Interventions: DRUG: Mifegyne ®|DRUG: Gymiso®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Pagibaximab Injection in Very Low Birth Weight Neonates for Prevention of Staphylococcal Sepsis
Status: COMPLETED
Conditions: Staphylococcal Sepsis
Interventions: DRUG: Placebo|DRUG: Pagibaximab 50 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LAGB as a Treatment for Morbid Obesity in Adolescents
Status: COMPLETED
Conditions: Morbid Obesity|Obstructive Sleep Apnea Syndrome|Metabolic Syndrome|Insulin Resistance|Nonalcoholic Fatty Liver Disease
Interventions: DEVICE: Laparoscopic adjustable gastric banding (Allergan Lap Band)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Defining the Molecular Risk in Israeli Patients With Secondary Compared to Primary Myelofibrosis
Status: UNKNOWN
Conditions: Myelofibrosis, Primary|Myelofibrosis, Post PV|Myelofibrosis, Post ET
Interventions: OTHER: Molecular analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Parallel Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of CKD-843 A
Status: COMPLETED
Conditions: Alopecia
Interventions: DRUG: CKD-843 A 45mg(Multiple dose)|DRUG: CKD-843 A 45mg|DRUG: CKD-843 A 55mg(Multiple dose)|DRUG: CKD-843 A 55mg|DRUG: CKD-843-R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanism of Masked Hypertension - Intervention
Status: WITHDRAWN
Conditions: Masked Hypertension
Interventions: DRUG: Carvedilol|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An RCT to Compare the Outcomes of Patients With Large Rotator Cuff Repair That Undergo Repair With or Without SIS
Status: UNKNOWN
Conditions: Rotator Cuff Tear
Interventions: PROCEDURE: porcine small intestine submucosa (SIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: To Assess Safety, Tolerability and Physiological Effects on Structure and Function of AXA4010 in Subjects With Sickle Cell Disease
Status: COMPLETED
Conditions: To Assess the Safety and Tolerabiltiy of an Amino Acid Composition in Subjects With Sickle Cell Disease|Anemia, Sickle Cell|Sickle Cell Anemia|Sickle Cell Disorders|Sickle Cell Disease
Interventions: DIETARY_SUPPLEMENT: AXA4010
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Influence of Oxytocin on the Startle Reflex and on Its Modulation
Status: UNKNOWN
Conditions: Psychiatric Disorders
Interventions: DRUG: Syntocinon®|DRUG: inactive nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gemcitabine and Carboplatin With or Without AZD2171 as First-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: cediranib maleate|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Er:YAG Laser Treatment for Female Stress and Mixed Urinary Incontinence (IncontiLase)
Status: COMPLETED
Conditions: Female Stress Urinary Incontinence|Mixed Incontinence, Urge and Stress
Interventions: DEVICE: IncontiLase Er:YAG laser treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Nivolumab Combined With Ipilimumab Versus Pemetrexed and Cisplatin or Carboplatin as First Line Therapy in Unresectable Pleural Mesothelioma Patients
Status: COMPLETED
Conditions: Mesothelioma
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thermovision-controlled Lumbar Sympathetic Blockade in Chronic Limb-threatening Ischemia Treatment
Status: RECRUITING
Conditions: Chronic Limb-Threatening Ischemia
Interventions: PROCEDURE: lumbar sympathetic blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2 Clinical Trial of CP-506 (HAP) in Monotherapy or With Carboplatin or ICI
Status: RECRUITING
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: CP-506|DRUG: Carboplatin|DRUG: Immune checkpoint inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Benefit of Оn-Line High Convection Volume Hemodiafiltration Treatment Versus High Flow Dialysis on Reduction of Oxidative Stress and Health Related Quality of Life in Dialysis Patients
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: PROCEDURE: HDF online
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of Routine Shave Margins Versus Standard Partial Mastectomy in Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: Shave margins|PROCEDURE: No Shave Margins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of SYM-1219 to Treat Bacterial Vaginosis
Status: COMPLETED
Conditions: Bacterial Vaginosis
Interventions: DRUG: SYM-1219|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CPAP Or Nasal Cannula Oxygen for Preterm Infants: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Infant, Newborn, Disease|Hypoxia|Respiratory Distress Syndrome|Bronchopulmonary Dysplasia
Interventions: PROCEDURE: Continuous positive airway pressure|PROCEDURE: Nasal Cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mind-body Therapy (Remotely Delivered) for Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BEHAVIORAL: Mind-body exercise and education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I, KM-819 in Healthy Subjects for Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: KM-819|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Safety and Efficacy Study of Hemodialysis Arteriovenous Fistulae Stenosis Treated With DissolveAV
Status: COMPLETED
Conditions: Fistulas Arteriovenous
Interventions: DEVICE: Dissolve AVF|DEVICE: Armada 35
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effects of US Bilateral Rectus Sheath Block for Laparoscopic GY Surgery
Status: COMPLETED
Conditions: Gynecologic Disease
Interventions: PROCEDURE: Rectus sheath block|DRUG: Ropivacaine|OTHER: Bandage|DRUG: IV-PCA containing Fentanyl and Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Venetoclax and Decitabine Assessment in Patients (≥60 - <75 Years) With Newly Diagnosed AML Eligible for Allo-SCT
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: COMBINATION_PRODUCT: Venetoclax and Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SHOrt Course Radiation and TASOX (TAS102 Plus Oxaliplatin) Chemotherapy in Operable Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DRUG: TAS 102|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Haldol/Diphenhydramine Versus Metoclopramide/Diphenhydramine for Treatment of Acute Headache in the Emergency Department: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Migraine Headaches|Nausea|Restlessness
Interventions: DRUG: Haloperidol|DRUG: Metoclopramide 10mg|DRUG: Diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of 2 Drugs on Lumbar Spine Volumetric BMD in Men With Glucocorticoid-Induced Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Teriparatide|DRUG: Risedronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Loaded Gait Training on Gross Motor Function in Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Conventional physical therapy program|OTHER: Loaded gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BE Study of Gaster®D Tab 20mg (Manufacturer Changed)
Status: UNKNOWN
Conditions: Gastroduodenal Ulcer
Interventions: DRUG: IGAD→GSTD|DRUG: GSTD→IGAD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gamification and Augmented Reality in Mechanical Ventilation Teaching for Nursing Students
Status: COMPLETED
Conditions: Gamification|Augmented Reality
Interventions: OTHER: Augmented Reality and Kahoot game learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Quercetin In The Treatment Of SARS-COV 2
Status: COMPLETED
Conditions: SARS (Severe Acute Respiratory Syndrome)
Interventions: DRUG: Quercetin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Shockwave and Myofascial Release Therapy in Chronic Pelvic Pain Syndrome
Status: NOT_YET_RECRUITING
Conditions: Chronic Pelvic Pain Syndrome
Interventions: DEVICE: extracorporeal shockwave|BEHAVIORAL: myofascial release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Pancreatic Enzymes in the Human Upper Intestine (Duodenum and Jejunum)
Status: TERMINATED
Conditions: Exocrine Pancreatic Insufficiency
Interventions: DRUG: pancrelipase|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Safety and Immunogenicity of an A (H1N1) 2009 Influenza Virus-like Particle (VLP) Vaccine
Status: COMPLETED
Conditions: Seasonal Influenza
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: A/H1N1 2009 Influenza VLP Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fisetin to Improve Physical Function in Stage I-III Breast Cancer Survivors
Status: RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Fisetin|DRUG: Placebo Administration|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Doxycycline for Elbow Tendinopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Lateral Epicondylitis|Lateral Epicondylitis, Left Elbow|Lateral Epicondylitis, Right Elbow|Lateral Epicondylitis, Unspecified Elbow|Lateral Epicondylitis (Tennis Elbow) Bilateral|Medial Epicondylitis|Medial Epicondylitis, Right Elbow|Medial Epicondylitis, Left Elbow
Interventions: DRUG: Doxycycline Hyclate 20 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ultra-low Dose Bevacizumab Plus Temozolomide for Recurrent High-grade Gliomas
Status: UNKNOWN
Conditions: Recurrent High-grade Glioma
Interventions: DRUG: Ultra-low dose Bevacizumab|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Needle and Shotblocker on Pain and Satisfaction in Intramuscular Injection Pain
Status: NOT_YET_RECRUITING
Conditions: Intramuscular Injection
Interventions: OTHER: Different methods used after intramuscular injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Fecal Microbial Transplantation in Combination With Immunotherapy in Melanoma Patients (MIMic)
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: DRUG: Fecal Microbial Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Phototherapy on Gait and Balance of Post-stroke Individuals
Status: COMPLETED
Conditions: Post-stroke in Association to Phototherapy
Interventions: DEVICE: Placebo or Active Phototherapy (MR4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Influence of tDCS on Cortical Plasticity in Patients With Dementia of the Alzheimer Type
Status: WITHDRAWN
Conditions: Dementia of Type Alzheimer
Interventions: DEVICE: transcranial direct current stimulation|DEVICE: sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Trial to Compare ADR of G-EYE™ Colonoscopy With Standard Colonoscopy
Status: UNKNOWN
Conditions: Adenoma|Polyps|Colorectal Cancer
Interventions: DEVICE: G-EYE™ Colonoscopy|DEVICE: Standard Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Transcranial Ultrasonography for the Management of Patients With Mild TBI
Status: RECRUITING
Conditions: Mild Traumatic Brain Injury
Interventions: PROCEDURE: Transcranial Doppler (TCD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating Length and Depth Estimation Accuracy of Laypersons and Health-Care Providers
Status: NOT_YET_RECRUITING
Conditions: Cardiopulmonary Resuscitation
Interventions: OTHER: Laypersons|OTHER: Health-Care Providers
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Kidney Precision Medicine Project (KPMP) - COVID-19 Protocol
Status: UNKNOWN
Conditions: Acute Kidney Failure|Acute Kidney Insufficiency|Acute Renal Failure|Acute Renal Injury|Acute Renal Insufficiency|Kidney Failure, Acute|Kidney Insufficiency, Acute|Renal Failure, Acute|Renal Insufficiency, Acute|Covid19|Sars-CoV-2 Infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PMCF Study to Evaluate Performance and Safety of "Xanoftal Next"
Status: COMPLETED
Conditions: Allergic Conjunctivitis|Dry Eye|Dry Eye Disease
Interventions: DEVICE: HPMC-HA eyedrops
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protective Effects of Saxagliptin (And Vitamin D3) on β Cell Function in Adult-onset Latent Autoimmune Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Saxagliptin|DRUG: Vitamin D3|DRUG: Insulin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Psychological-behavioral Intervention for Physical Activity in Type 2 Diabetes
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: BEHAVIORAL: Positive Psychology + Motivational Interviewing|BEHAVIORAL: MI-based Health Education Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rest to Overcome Loss and Reduce Risk
Status: ACTIVE_NOT_RECRUITING
Conditions: Sleep Disturbance|Inflammation|Quality of Life|Bereavement|Spouses
Interventions: BEHAVIORAL: Targeted Cognitive Behavior Therapy for Insomnia|OTHER: Information-Only Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Darunavir/Ritonavir + Lamivudine Versus Continuing With Darunavir/Ritonavir + Tenofovir/Emtricitabine or Abacavir/Lamivudine in HIV Infected Subject
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Darunavir/Ritonavir|DRUG: Lamivudine|DRUG: Emtricitabine/tenofovir or abacavir/lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Chios Mastic Water in Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: BEHAVIORAL: Chios mastic water|BEHAVIORAL: Placebo water|BEHAVIORAL: Chios mastic fruit juice|BEHAVIORAL: Placebo fruit juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone-Eluting Stent in Acute Coronary Syndrome to Prevent Restenosis
Status: COMPLETED
Conditions: Vessel Restenosis
Interventions: DEVICE: Dexamethasone-Eluting Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Efficacy and Safety of GNR-060 vs Metalyse in Patients With ST Elevation Myocardial Infarction
Status: RECRUITING
Conditions: ST Elevation Myocardial Infarction
Interventions: BIOLOGICAL: GNR-060|BIOLOGICAL: Metalyse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary or Secondary Drowning
Status: NOT_YET_RECRUITING
Conditions: Drowning|Drowning; Anoxia|Drowning, Near|Drowning in Swimming Pool|Drowning; Asphyxia|Drowning/Diving/SCUBA Accident|Drowning or Immersion of Unknown Intent|Drowning and Submersion, Undetermined Intent|Drowning and Submersion While in Bath-Tub|Drowning and Submersion While in Natural Water|Drowning and Submersion Due to Sailboat Sinking|Drowning and Submersion Due to Fall Off Ship|Drowning and Submersion While in Swimming-Pool
Interventions: OTHER: Drowning
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and IOP-Lowering Effects of WB007
Status: COMPLETED
Conditions: Glaucoma, Primary Open Angle|Ocular Hypertension
Interventions: DRUG: WB007 0.05%|DRUG: WB007 0.15%|DRUG: WB007 0.4%|DRUG: Timolol 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Evaluate the Efficacy and Safety of JointStem in Treatment of Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: JointStem|DRUG: Synvisc-One
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Virtual Acute Care at Home Experience
Status: ENROLLING_BY_INVITATION
Conditions: Conditions|Infections|Heart Failure|Renal and Urinary Disorders|Diabetes|Hypertension|Fever|Bronchitis|Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Interventions: OTHER: Digital Care Solution as supportive personalized care|OTHER: Traditional Hospital Level Care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 2-Hydroxybenzylamine (2-HOBA) to Reduce HDL Modification and Improve HDL Function in Familial Hypercholesterolemia (FH)
Status: RECRUITING
Conditions: Familial Hypercholesterolemia
Interventions: DRUG: 2-Hydroxybenzylamine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of TRC105 and Pazopanib Versus Pazopanib Alone in Patients With Advanced Angiosarcoma
Status: COMPLETED
Conditions: Advanced Angiosarcoma
Interventions: BIOLOGICAL: TRC105|DRUG: Votrient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Validation and Efficacy of Varix Trainer as a Training Device Esophagogastroduodenoscopy (a Multicenter Study)
Status: RECRUITING
Conditions: Gastric Varix
Interventions: OTHER: Endoscopy training curriculum
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Immobilization of the Metacarpophalangeal Joint in Thumb Osteoarthritis
Status: COMPLETED
Conditions: Hand Osteoarthritis
Interventions: DEVICE: Whale orthosis|DEVICE: Colditz orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Single and Multiple Ascending Doses of VIB1116 in Rheumatic Diseases
Status: COMPLETED
Conditions: Dendritic Cell -Mediated Rheumatic Diseases
Interventions: DRUG: VIB1116|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Precise Local Injection of Anti-cancer Drugs Using Presage's CIVO Device in Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Soft Tissue Sarcoma Adult
Interventions: DRUG: Multiple drug microinjection|DEVICE: CIVO device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Erlotinib and Cetuximab in Treating Patients With Advanced Solid Tumors With Emphasis on Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: cetuximab|DRUG: erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olanzapine for Cancer Related Anorexia-cachexia Syndrome
Status: RECRUITING
Conditions: Anorexia|Cachexia
Interventions: DRUG: Olanzapine 2.5 MG|DRUG: Olanzapine 5 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Culturally-tailored Personalized Nutrition Intervention in South Asian Women at Risk of Gestational Diabetes
Status: RECRUITING
Conditions: Diabetes, Gestational
Interventions: BEHAVIORAL: Dietary Intervention|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Interventions for the Management of Perineal Cancer Pain
Status: NOT_YET_RECRUITING
Conditions: Cancer Rectum|Cancer Vulva|Cancer Vagina
Interventions: DEVICE: cooled radiofrequency ,|DEVICE: conventional radiofrequency|DEVICE: neurolysis of ganglion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Decitabine Given Subcutaneously to Adults With Low or Intermediate-1 Risk Myelodysplastic Syndromes (MDS)
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: decitabine|DRUG: decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pressure Release of Myofascial Trigger Points on Mechanical Neck Pain.
Status: RECRUITING
Conditions: Myofascial Pain Syndrome of Neck|Trigger Point Pain, Myofascial|Myofacial Pain
Interventions: OTHER: Myofascial trigger points pressure release|OTHER: Therapeutic exercise and postural hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Psycho-educational Group (PEG) Intervention on Supportive Care and Survivorship Issues in Early-stage Breast Cancer Survivors Who Have Received Systemic Treatment
Status: COMPLETED
Conditions: Breast Cancer|Cancer|Anxiety|Cognitive Dysfunction
Interventions: BEHAVIORAL: Psychoeducation group|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Multicenter Register for Children and Young Adults With Intracranial Localized Medulloblastoma, CNS-PNET or Ependymoma
Status: COMPLETED
Conditions: Medulloblastoma, Childhood|Cerebral Primitive Neuroectodermal Tumor|Ependymoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rituximab Augmentation Following R-CHOP Induction Chemotherapy in Extremely Elderly Patients With Diffuse Large B Cell Lymphoma
Status: UNKNOWN
Conditions: Lymphoma, Large B-cell, Diffuse
Interventions: DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pathway M-1: Sphenopalatine Ganglion Stimulation for the AcuteTreatment of High Disability Migraine Headache
Status: COMPLETED
Conditions: High Frequency, High Disability Migraine
Interventions: DEVICE: ATI Neurostimulation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Olaparib Tablets as a Treatment for Ovarian Cancer Subjects With Different HRD Tumor Status
Status: COMPLETED
Conditions: Relapsed Ovarian Cancer, BRCA Mutation, Platinum Sensitivity
Interventions: DRUG: OLAPARIB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin With or Without Sildenafil, With Analysis of Cardiac Markers
Status: COMPLETED
Conditions: Breast Cancer|Gastrointestinal Cancer|Genitourinary Cancer|Sarcoma|Gynecologic Cancer
Interventions: DRUG: Doxorubicin|DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Low-level Laser Therapy on Stability and Displacement of Orthodontic Miniscrew Implants
Status: COMPLETED
Conditions: Displacement of Other Bone Devices, Implants and Grafts|Mechanical Complication of Other Bone Devices, Implants and Grafts
Interventions: PROCEDURE: Low-level laser therapy|PROCEDURE: Mediate force application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study To Assess the Safety and Effects of OnabotulinumtoxinA (BOTOX) Intramuscular Injection in Adult Participants With Moderate to Severe Platysma Prominence
Status: COMPLETED
Conditions: Platysma Prominence
Interventions: DRUG: OnabotulinumtoxinA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Human Fibrinogen Concentrate in Pediatric Cardiac Surgery
Status: COMPLETED
Conditions: Hypofibrinogenemia|Afibrinogenemia|Bleeding Disorders
Interventions: DRUG: RiaStAP|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: F-18 Fluorothymidine PET Imaging for Early Evaluation of Response to Therapy in Head & Neck Cancer Patients
Status: COMPLETED
Conditions: Mouth Neoplasms|Oropharyngeal Neoplasms|Laryngeal Neoplasms|Head and Neck Neoplasms
Interventions: DRUG: 18F-Fluorothymidine PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Ultiva ® Associated With Xylocaine ® in the Procedures of Feticide
Status: COMPLETED
Conditions: Termination of Pregnancy|Feticide
Interventions: DRUG: Remifentanil + Lidocaïne|DRUG: Sufentanil + Lidocaïne
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Safety, Tolerability, Immunogenicity and Preliminary Efficacy of ITI-1001 In Patients With Newly Diagnosed Glioblastoma (GBM)
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: ITI-1001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methylprednisolone Pulse Macrolide Therapy for Refractory Mycoplasma Pneumoniae Pneumonia in Children
Status: TERMINATED
Conditions: Refractory Mycoplasma Pneumoniae Pneumonia
Interventions: DRUG: methylprednisolone|DRUG: azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation With BiopH+Psoriasis Medical Bath in Subject With Mild to Moderate Plaque Psoriasis.
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DEVICE: BIOpH+ Psoriasis Medical Bath|DEVICE: Cetaphil Moisturizing Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The StUdy to Evaluate the Performance and safEty of the Novasight HybRid System Using Objective PeRformance Criteria
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: Intravascular imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial Comparing the Pharmacokinetic Properties of Fast-acting Insulin Aspart Between Children, Adolescents and Adults With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: Faster aspart|DRUG: Insulin aspart (NovoRapid®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Lapaquistat Acetate Alone or Combined With High-Dose Statin Therapy in Subjects With Hypercholesterolemia
Status: TERMINATED
Conditions: Hypercholesterolemia
Interventions: DRUG: Lapaquistat acetate and stable statin therapy|DRUG: Stable statin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 24-hour IOP Fluctuation Profile Recorded With SENSIMED Triggerfish in Primary Open-angle Glaucoma (POAG) Patients After Cataract Surgery
Status: WITHDRAWN
Conditions: Glaucoma
Interventions: DEVICE: Phacoemulsification with implantation of intraocular lens (CE-IOL) SENSIMED Triggerfish
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improving Cognitive Function Through High-intensity Interval Training in Breast Cancer Patients Undergoing Chemotherapy
Status: RECRUITING
Conditions: Breast Cancer|Chemotherapy Effect|Exercise Therapy|Cognitive Change
Interventions: BEHAVIORAL: High-Intensity Intervals Training|OTHER: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Smoked Marijuana on Risk Taking and Decision Making Tasks
Status: COMPLETED
Conditions: Marijuana Use Disorder
Interventions: DRUG: Inactive Marijuana (0% THC)|DRUG: Low THC marijuana (1.8 %THC)|DRUG: High THC marijuana (3.9% THC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation the Efficacy and Safety of Mutiple Lenzumestrocel (Neuronata-R® Inj.) Treatment in Patients With ALS
Status: ACTIVE_NOT_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: BIOLOGICAL: Lenzumestrocel|DRUG: Riluzole|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eisenhower's Alternative Speculum Examination
Status: WITHDRAWN
Conditions: Papanicolaou Smear
Interventions: PROCEDURE: no-stirrup vaginal examination|PROCEDURE: Vaginal speculum examination done with stirrups.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING