pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Efficacy of ESTRATEST® Tablets in Relieving Menopausal Symptoms in Estrogenized, Non-Hysterectomized Postmenopausal Women
Status: TERMINATED
Conditions: Menopause
Interventions: DRUG: esterified estrogens 1.25 mg and methyltestosterone 2.5 mg|DRUG: Esterified estrogens 1.25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Two Cognitive Batteries in People With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: OTHER: CDR Computerized Cognitive Assessment System|OTHER: MATRICS Consensus Cognitive Battery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Silodosin Versus Tamsulosin for Treatment of Ureteral Stones
Status: TERMINATED
Conditions: Ureteral Calculus|Ureterolithiasis|Ureteral Stone
Interventions: DRUG: Silodosin|DRUG: Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lactobacillus Reuteri Supplementation in the Treatment of Infantile Colic
Status: WITHDRAWN
Conditions: Infantile Colic
Interventions: DIETARY_SUPPLEMENT: Lactobacillus reuteri DSM17938 probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Safety and Performance of SenSura Test Product in Subjects With Ileostomy
Status: COMPLETED
Conditions: Stoma Ileostomy
Interventions: DEVICE: SenSura|DEVICE: SenSura test product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1/2 Study of AEB1102 in Patients With Arginase I Deficiency
Status: COMPLETED
Conditions: Arginase I Deficiency|Hyperargininemia
Interventions: DRUG: AEB1102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Hydrocortisone in Very Preterm High-Risk Infants
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia|Encephalomalacia|Premature Birth
Interventions: DRUG: Hydrocortisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Time Restricted Eating and Innate Immunity
Status: COMPLETED
Conditions: Time Restricted Feeding|Myocardial Infarction|Atherosclerotic Cardiovascular Disease
Interventions: BEHAVIORAL: Time restricted eating (TRE)|BEHAVIORAL: Regular diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Postoperative Anal Function Between Parks and Bacon Techniques in Low Rectal Cancer
Status: RECRUITING
Conditions: Rectal Neoplasms|Low Anterior Resection Syndrome|Anastomotic Leak|Quality of Life
Interventions: PROCEDURE: Parks technique|PROCEDURE: Bacon technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hysteroscopic Guided Versus Ultrasound Guided Extraction of Retained IUD
Status: NOT_YET_RECRUITING
Conditions: Contraceptive Device; Complications
Interventions: PROCEDURE: Office hysteroscopy|PROCEDURE: Ultrasound guided
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided ESP Block Versus Intrathecal Morphine for Postoperative Analgesia in Major HPB Surgery.
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Erector Spinae Plane Block|PROCEDURE: Intrathecal morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Beta-cell Function in Glucose Abnormalities and Acute Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction|Unstable Angina Pectoris|Diabetes Mellitus|Impaired Glucose Tolerance
Interventions: DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pregabalin Premedication for Conscious Sedation
Status: COMPLETED
Conditions: Conscious Sedation
Interventions: DRUG: Pregabalin (PG)|DRUG: Control placebo (C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Consuming Red Meat on the Gut Microbiota in Young Adults
Status: COMPLETED
Conditions: Diet Modification
Interventions: OTHER: Controlled Lacto-ovo vegetarian diet|OTHER: Controlled Unprocessed red meat diet|OTHER: Controlled processed red meat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Japi: Cognitive, Emotional and Social Stimulation for Preschool Children
Status: RECRUITING
Conditions: Behavioral Problem of Child
Interventions: BEHAVIORAL: JAPI: Cognitive, Emotional and Social Stimulation for Preschool Children
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Digital Mental Health Intervention for Nonsuicidal Self-Injury in Young Adults
Status: NOT_YET_RECRUITING
Conditions: Nonsuicidal Self Injury|Suicidal Ideation|Depression|Anxiety
Interventions: BEHAVIORAL: Self-guided digital intervention for NSSI|BEHAVIORAL: Digital intervention for NSSI with coaching|BEHAVIORAL: Active control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation to Evaluate the Suitability of StrokeWave in Distinguishing Haemorragic From Ischaemic Strokes
Status: RECRUITING
Conditions: Stroke, Ischemic|Stroke Hemorrhagic
Interventions: DEVICE: Device: clinical investigation microwave device class IIa not marked CE for stroke detection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cardiovascular Risk Reduction Program Aimed at African American Women (The HHER Lifestyle Program)
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: BEHAVIORAL: Basic Educational and Counseling Program|BEHAVIORAL: Comprehensive Educational and Counseling Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Structured School-based Health Intervention for the Obesity Prevention
Status: NOT_YET_RECRUITING
Conditions: Child Obesity|Child Behavior|Obesity, Childhood
Interventions: BEHAVIORAL: Structured school-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Non Invasive Ventilation : Efficacy of a New Ventilatory Mode in Patients With OHS
Status: COMPLETED
Conditions: Obesity Hypoventilation Syndrome
Interventions: DEVICE: BiPAP - A40|DEVICE: BiPAP - ST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot-study: Non-thermal Ablation Using Irreversible Electroporation to Treat Colorectal Liver Metastases
Status: COMPLETED
Conditions: Colorectal Liver Metastases|Metastatic Liver Disease
Interventions: DEVICE: Irreversible electroporation (IRE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of an Intervention Program on Parenting Stress After Preterm Birth
Status: COMPLETED
Conditions: Preterm Birth|Parenting|Mental Health Wellness 1|Parent-Child Relation|Child Development
Interventions: OTHER: Triadic parent-infant Relationship Therapy (TRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Intraorbital Injection Versus Oral Steroid in Anterior Idiopathic Orbital Inflammation
Status: RECRUITING
Conditions: Orbital Pseudotumor
Interventions: DRUG: Prednisolone|DRUG: Triamcinolone + Betamethason
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brinzolamide-brimonidine Fixed Combination for Preventing IOP Elevation After Intravitreal Anti-VEGF Injections
Status: COMPLETED
Conditions: Eye Diseases|Injection Complication|Intraocular Pressure
Interventions: DRUG: Brinzolamide-brimonidine Fixed Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety and Efficacy of ATI-2173 and Vebicorvir in Combination With Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis B Virus Infection
Status: TERMINATED
Conditions: Chronic Hepatitis b
Interventions: DRUG: ATI-2173 25mg|DRUG: Vebicorvir 300mg|DRUG: Viread 300Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Exploratory Efficacy of IMS001 in Subjects With Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: IMS001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Success Rate of Catheter Insertion by the Presence of Obturator During Peripherally Inserted Central Venous Catheter
Status: ACTIVE_NOT_RECRUITING
Conditions: Central Venous Catheters
Interventions: OTHER: turbo-ject PICC set
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MS-20 on Patients With Ulcerative Colitis(UC)
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: MS-20 oral solution|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Esketamine on Conscious State in Patients With pDoC
Status: RECRUITING
Conditions: Esketamine|Consciousness Disorders
Interventions: DRUG: Esketamine|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Baricitinib, Placebo and Antiviral Therapy for the Treatment of Patients With Moderate and Severe COVID-19
Status: TERMINATED
Conditions: Symptomatic COVID-19 Infection Laboratory-Confirmed
Interventions: DRUG: Baricitinib|DRUG: Hydroxychloroquine|DRUG: Placebo Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Intensity-modulated Radiotherapy in Patients With Squamous Cell Carcinoma of Unknown Primary (SCCUP) of the Head and Neck
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Efficacy and Safety of Lopinavir/Ritonavir Monotherapy Versus Darunavir/Ritonavir Monotherapies as Simplification Switching Strategies of PI/NNRTI-Triple Therapy Based-Regimens
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Darunavir/ritonavir|DRUG: Lopinavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Long Term Safety of OTX-TP (Sustained Release Travoprost) Intracanalicular Insert
Status: COMPLETED
Conditions: Open Angle Glaucoma and Ocular Hypertension
Interventions: DRUG: Ophthalmic Insert
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety and Tolerability of a New Inhaled Formulation of RV568 in Healthy Volunteers
Status: COMPLETED
Conditions: COPD|Healthy Volunteers
Interventions: DRUG: RV568 single dose|DRUG: RV568 matching placebo single dose|DRUG: RV568 repeat dose|DRUG: RV568 matching placebo repeat dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Designed Physical Training After Selective Dorsal Rhizotomy on Motor Function of Ambulant Children With Spastic Diplegia
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Concomitant physical rehabilitation|OTHER: Standard Orthotic Management|OTHER: selective dorsal rhizotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Inspiratory Muscle Training Improves the Severity of Obstructive Sleep Apnea and Sleep Quality?
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: OTHER: Inspiratory Muscle Training|OTHER: Inspiratory Muscle Training Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of the Influence of the Diffuse Noxious Inhibitory Controls of the Pain on the Efficacy of Milnacipran in Fibromyalgia Therapy
Status: UNKNOWN
Conditions: Fibromylagia
Interventions: DRUG: Milnacipran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab (MK-3475) Monotherapy in Locally Advanced/Metastatic Renal Cell Carcinoma (MK-3475-427/KEYNOTE-427)
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 6-month Safety and Benefit Study of ADVAIR in Children 4-11 Years Old
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: ADVAIR 100/50mcg|DRUG: ADVAIR 250/50mcg|DRUG: FLOVENT 100mcg|DRUG: FLOVENT 250mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Maternal and Child Health in India: Evaluating Demand and Supply Side Strategies (IMATCHINE)
Status: COMPLETED
Conditions: Obstetric Labor Complications|Post-partum Hemorrhage|Sepsis|Pre-eclampsia|Neonatal Mortality
Interventions: OTHER: Experimental: Treatment 1|OTHER: Experimental: Treatment 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pembrolizumab and Olaparib in Cervical Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Cancer|Cervical Carcinoma
Interventions: DRUG: pembrolizumab|DRUG: olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of High Protein Diet in Stroke Patients With Low Muscle Mass
Status: COMPLETED
Conditions: Ischemic Stroke|Diet, Healthy|Muscle Loss
Interventions: DIETARY_SUPPLEMENT: high protein diet|DIETARY_SUPPLEMENT: normal protein diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PREMIX vs PREMED Intranasal Lidocaine and Midazolam
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Lidocaine|DRUG: Lidocaine and midazolam (PREMIX)|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genetic Polymorphysm of Cholesterol 24 S Hydroxylase in Patients With Glaucoma and AMD
Status: COMPLETED
Conditions: Glaucoma
Interventions: BIOLOGICAL: Assessing the blood level of cholesterol 24 S Hydroxylase|BIOLOGICAL: Assessing the blood level of cholesterol 24 S hydroxylase|BIOLOGICAL: assessing the blood level of cholesterol 24 S hydroxylase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Concussion in Motor Vehicle Accidents: The Concussion Identification Index
Status: COMPLETED
Conditions: Motor Vehicle Accidents|TBI (Traumatic Brain Injury)|Brain Contusion|Brain Injuries|Cortical Contusion|Concussion Mild|Cerebral Concussion|Brain Concussion|Accidents, Traffic|Traffic Accidents|Traumatic Brain Injury With Brief Loss of Consciousness|Traumatic Brain Injury With no Loss of Consciousness|Traumatic Brain Injury With Loss of Consciousness
Interventions: OTHER: The Concussion Identification Index|OTHER: ImPACT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Evaluation of Efficacy of Shield Force Plus Varnish VS Sodium Fluoride on Dentin Hypersensitivity
Status: UNKNOWN
Conditions: Dentin Hypersensitivity|Dentin Desensitizing Agents
Interventions: DRUG: TOKUYAMA SHIELD FORCE PLUS|DRUG: Sodium Fluoride 5% Dental Varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-Intensity Shockwave Therapy to Treat Erectile Dysfunction and Preserve Erectile Function After Prostate Cancer Surgery
Status: RECRUITING
Conditions: Erectile Dysfunction|Localized Prostate Carcinoma|Stage I Prostate Cancer AJCC v8|Stage II Prostate Cancer AJCC v8|Stage III Prostate Cancer AJCC v8
Interventions: PROCEDURE: Nerve-Sparing Prostatectomy|OTHER: Medical Device Usage and Evaluation|PROCEDURE: Duplex Ultrasound|OTHER: Survey Administration|PROCEDURE: Nerve-Sparing Prostatectomy|PROCEDURE: Sham Intervention|PROCEDURE: Duplex Ultrasound|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PLGA Nanoparticles Entrapping Ciprofloxacin to Treat E-Fecalis Infections in Endodontics
Status: COMPLETED
Conditions: Bacterial Infections Oral
Interventions: DEVICE: Chitosan Coated PLGA nanoparticles entrapping Ciprofloxacin incorporated in smart gels|DEVICE: Ciprofloxacin paste and solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Healthy Eating and Active Playtime by Connecting Preschool Children to Nature
Status: UNKNOWN
Conditions: Sedentary Lifestyle|Overweight|Eating Disorders
Interventions: OTHER: Healthy lifestyle|OTHER: physical activity and dietary guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Irinotecan and Cytarabine in Treating Patients With Refractory or Recurrent Acute Myeloid Leukemia or Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: cytarabine|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: QUILT-3.088: NANT Pancreatic Cancer Vaccine
Status: WITHDRAWN
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Gemcitabine|DRUG: Nab-paclitaxel|DRUG: Aldoxorubicin HCl|BIOLOGICAL: ALT-803|BIOLOGICAL: ETBX-011|BIOLOGICAL: ETBX-021|BIOLOGICAL: ETBX-051|BIOLOGICAL: ETBX-061|BIOLOGICAL: GI-4000|BIOLOGICAL: GI-6207|BIOLOGICAL: GI-6301|BIOLOGICAL: haNK|DRUG: Avelumab|DRUG: Bevacizumab|DRUG: Capecitabine|DRUG: Cyclophosphamide|DRUG: 5-Fluorouracil|DRUG: Leucovorin|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 4, Placebo-Controlled, Randomized Study to Evaluate the Immunogenicity and Safety of HPV and Tdap When Administered With MenACWY in Adolescents
Status: COMPLETED
Conditions: Meningococcal Meningitis
Interventions: BIOLOGICAL: Placebo + Combined Tetanus, Reduced Diphtheria Toxoid, Acellular Pertussis Vaccine + Quadrivalent Human Papillomavirus Vaccine|BIOLOGICAL: MenACWY-CRM Conjugate Vaccine + Combined Tetanus, Reduced Diphtheria Toxoid, Acellular Pertussis Vaccine + Quadrivalent Human Papillomavirus Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety of Intuvax Administered Intra-tumorally in Patients With Gastrointestinal Stromal Tumors
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumor
Interventions: BIOLOGICAL: Intuvax (ilixadencel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety and Efficacy of AR-15512
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: AR 15512 Ophthalmic Solution|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Texting to Promote Tobacco Abstinence in Emergency Department Smokers: A Pilot Study
Status: COMPLETED
Conditions: Smoking|Tobacco Abstinence
Interventions: OTHER: Smokefree TXT Program|DRUG: nicotine replacement patches|DRUG: Nicotine Replacement Gum|BEHAVIORAL: Faxed Referral CT Smokers Quitline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Study to Investigate the Safety and Efficacy of Replenine®-VF in Severe Haemophilia B Patients
Status: COMPLETED
Conditions: Haemophilia B
Interventions: BIOLOGICAL: Replenine®-VF (High Purity Factor IX)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Tolerance of Combination Anti-HIV Drug Therapy (Indinavir, Lamivudine, and Zidovudine) in HIV-Positive Pregnant Women and Their Infants
Status: COMPLETED
Conditions: HIV Infections|Pregnancy
Interventions: DRUG: Indinavir sulfate|DRUG: Lamivudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: A 4 Year Combination Therapy of Growth Hormone and (GnRH) Agonist in Children With a Short Predicted Height
Status: ACTIVE_NOT_RECRUITING
Conditions: Idiopathic Short Stature
Interventions: DRUG: somatropin|DRUG: triptorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dexmedetomidine in Patients With Agitated Delirium in Palliative Care
Status: RECRUITING
Conditions: Hyperactive Delirium|Delirium of Mixed Origin
Interventions: DRUG: Dexmedetomidine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Photodynamic Therapy With Urucum and LED and Probiotics in Halitosis Reduction
Status: COMPLETED
Conditions: Halitosis
Interventions: OTHER: Teeth brushing and flossing|OTHER: Tongue scraping|RADIATION: Antimicrobial Photodynamic Therapy (aPDT)|BIOLOGICAL: Probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bilevel Versus Servoventilation in Complex Sleep Apnea
Status: COMPLETED
Conditions: Complex Sleep Apnea|CPAP Induced Central Sleep Apnea
Interventions: DEVICE: Bilevel therapy (somnovent ST 22, Weinmann, Hamburg, Germany)|DEVICE: servoventilation (Somnovent CR, Weinmann, Hamburg, Germany)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility and Acceptability Pilot Study Evaluating a Patient-Specific Targeted Intervention Using Patient Navigators or Routine Clinical Care
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Navigator Phone Calls|BEHAVIORAL: Exit Interview
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Safety and Usability of the MAK Exoskeleton in Patients With Stroke
Status: COMPLETED
Conditions: Stroke|Gait, Hemiplegic
Interventions: DEVICE: Physical Rehabilitation with MAK exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk Factors for Falls After Intervention of the Urgent Medical Assistance Service (SAMU) in the Elderly Person at Home
Status: COMPLETED
Conditions: Elderly
Interventions: OTHER: standardized gerontological evaluation (EGS)|OTHER: Proposal for a personalized intervention plan (PIP)|OTHER: Follow-up|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Medical and Surgical Treatments of Benign Prostate Hyperplasia in Patients Who Have Low Grade Non Muscle Invasive Bladder Cancer for Tumour Recurrence and Progression
Status: UNKNOWN
Conditions: Bladder Cancer
Interventions: PROCEDURE: Transurethral Resection|DRUG: Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Acetaminophen For Postoperative Pain in the Neonatal Intensive Care Unit
Status: RECRUITING
Conditions: Pain, Postoperative|Pain
Interventions: DRUG: Acetaminophen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Community Collaboration to Advance Racial/Ethnic Equity in CRC Screening
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: OTHER: FIT kit Screening Test|OTHER: Cologuard Screening Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Trial to Establish the Feasibility of Combining Either the Tyrosine Kinase Inhibitor AC220,CXCR4 Inhibitor Plerixafor or HSP90 Inhibitor Ganetespib With Chemotherapy in Older Patients With Acute Myeloid Leukaemia and High Risk Myelodysplastic Syndrome.
Status: COMPLETED
Conditions: Acute Myeloid Leukaemia|High Risk Myelodysplastic Syndrome
Interventions: DRUG: Plerixafor|DRUG: AC220|DRUG: Ganetespib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Positron Emission Tomography (PET) Study to Determine Central mGluR5 Receptor Occupancy of AZD2516
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD2516
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness, Feasibility and Acceptability of Seasonal Malaria Chemoprevention in Aweil South County in South Sudan
Status: ACTIVE_NOT_RECRUITING
Conditions: Malaria
Interventions: DRUG: Sulfadoxine pyrimethamine|DRUG: Amodiaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: External-Beam Radiation Therapy Compared With Vaginal Brachytherapy After Surgery for Stage I Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: RADIATION: External Beam Radiation Therapy|RADIATION: Vaginal Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Towards Understanding Between ADT Treatment, Circadian Rhythm, and Physiological Responsiveness
Status: RECRUITING
Conditions: Prostatic Neoplasm|Survivorship|Frailty|Aging
Interventions: BEHAVIORAL: Dietary recommendations|BEHAVIORAL: Time-restricted eating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: AmbassADDOrs for Health Study
Status: RECRUITING
Conditions: HIV Infections
Interventions: BEHAVIORAL: Loyalty card program at drug shops & supply of HIVST and SRH products|BEHAVIORAL: Comparison drug shops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Lenvatinib Following Liver Transplantation in Patients With High-Risk Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Lenvatinib|DRUG: Placebo|DRUG: Immunosuppressive regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Methylprednisolone Versus Oral Prednisolone for Infantile Spasms
Status: UNKNOWN
Conditions: Infantile Spasm
Interventions: DRUG: Intravenous Methylprednisolone|DRUG: Oral Pednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Self-Thai Foot Massage on Pain, Range of Motion and Functional Disability in Type 2 DM
Status: NOT_YET_RECRUITING
Conditions: Peripheral Diabetic Neuropathy
Interventions: OTHER: Self-Thai Foot Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Post Marketing Study of MagnetOs Putty Compared to Demineralized Bone Matrix (DBM) Mixed With Autograft in Patients Undergoing Posterolateral Lumbar Fusion
Status: NOT_YET_RECRUITING
Conditions: Degenerative Disc Disease|Spine Fusion
Interventions: DEVICE: MagnetOs Putty|DEVICE: Demineralized Bone Matrix mixed with Autograft Bone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NEM® Versus Placebo on Exercise-induced Joint Pain, Stiffness, & Cartilage Turnover In Healthy, Post-Menopausal Women
Status: COMPLETED
Conditions: Exercise-induced Joint Pain Stiffness and Cartilage Turnover
Interventions: DIETARY_SUPPLEMENT: NEM|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mitigating Racial Disparities in Shared Decision Making in the Intensive Care Unit
Status: NOT_YET_RECRUITING
Conditions: Health Care Disparities
Interventions: BEHAVIORAL: Shared decision making tip sheet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Long-term Safety, Pharmacodynamics, and Exploratory Efficacy of GZ/SAR402671 in Treatment-Naïve Adult Male Patients With Fabry Disease
Status: COMPLETED
Conditions: Fabry Disease
Interventions: DRUG: GZ/SAR402671
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness and Self-compassion Focussed Walking
Status: UNKNOWN
Conditions: Breast Cancer|Fatigue
Interventions: BEHAVIORAL: Mindfulness and Self-Compassion focussed exercises during walking training|BEHAVIORAL: Walking training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy Study on Trabectedin in Retroperitoneal Leiomyosarcoma and Well Differentiated/Dedifferentiated Liposarcoma
Status: COMPLETED
Conditions: Liposarcoma|Leiomyosarcoma
Interventions: DRUG: Trabectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial on the Acceptability of Modified Lipid Based Nutrient Supplements Among Malawian Infants
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: Nutributter|DIETARY_SUPPLEMENT: LNS-20gM|DIETARY_SUPPLEMENT: LNS-20gNoM|DIETARY_SUPPLEMENT: LNS-10gM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Inhaled Cannabis for Acute Migraine Treatment
Status: COMPLETED
Conditions: Migraine|Cannabis|THC|CBD
Interventions: DRUG: THC ~5%|DRUG: CBD ~12%|DRUG: THC ~5% and CBD ~12%|DRUG: Sham Cannabis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of Contemporary Labor Patterns Measured Via Transperineal Ultrasonography
Status: UNKNOWN
Conditions: Pregnancy|Obstetric Labor
Interventions: DEVICE: Transperineal ultrasonography, General Electric Healthcare Voluson Ultrasound System|DEVICE: Cardiotocography, Bionet FC1400 Fetal Monitor|OTHER: Amniotomy|DRUG: Analgesics, Opioid, Meperidine|DRUG: Labor augmentation, Oxytocin|DRUG: Labor induction, Oxytocin|DRUG: Cervical ripening, labor induction, Dinoprostone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Fluoride Varnish X Glass Ionomer Sealant on Cervical Dentin Hypersensitivity
Status: COMPLETED
Conditions: Dentin Hypersensitivity|Dentin Sensitivity
Interventions: DRUG: Fluoride Varnish|DRUG: Glass Ionomer Sealant|OTHER: Placebo Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing HIV Risk Among Episodic Substance Using Men Who Have Sex With Men (SUMSM)
Status: COMPLETED
Conditions: HIV Infections|Episodic Substance Use
Interventions: BEHAVIORAL: Adapted Personalized Cognitive Risk-reduction Counseling intervention (PCC)|BEHAVIORAL: Standard HIV testing with information only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness and Safety of a Water-based and a Silicone-based Personal Lubricants With Sensory Action
Status: COMPLETED
Conditions: Dyspareunia|Vaginal Dryness
Interventions: DEVICE: Lubricant A (sensate water-based personal lubricant) and Comparator A (non-sensate water-based lubricant)|DEVICE: Lubricant B (sensate silicone-based personal lubricant) and Comparator B (non-sensate silicone-based personal lubricant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of SCH 530348 2.5 mg Tablets (P06558)
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Pantoprazole|DRUG: SCH 530348 (high percentage)|DRUG: SCH 530348 (standard percentage)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Resistant aHUS
Status: COMPLETED
Conditions: Atypical Hemolytic Uremic Syndrome
Interventions: DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic, Physical Fitness and Mental Health Effects of High Intensity Interval Training (HIIT) in Adolescents With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: OTHER: HIGH INTENSITY INTERVAL TRAINING
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage III Gastric Cancer AJCC v8|Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Clinical Stage IV Gastric Cancer AJCC v8|Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8|Locally Advanced Gastric Adenocarcinoma|Locally Advanced Gastroesophageal Junction Adenocarcinoma|Locally Advanced Urothelial Carcinoma|Metastatic Gastric Adenocarcinoma|Metastatic Gastroesophageal Junction Adenocarcinoma|Metastatic Head and Neck Squamous Cell Carcinoma|Metastatic Lung Non-Small Cell Carcinoma|Metastatic Malignant Solid Neoplasm|Metastatic Melanoma|Metastatic Urothelial Carcinoma|Recurrent Head and Neck Squamous Cell Carcinoma|Refractory Lung Non-Small Cell Carcinoma|Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8|Stage IV Lung Cancer AJCC v8|Unresectable Malignant Solid Neoplasm|Unresectable Melanoma
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Sonidegib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Individualized Imagery Scripts on Sleep, Psychosis, and Suicidality Among Inpatients With Psychosis
Status: NOT_YET_RECRUITING
Conditions: Psychosis
Interventions: BEHAVIORAL: Individualized imagery|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability and Efficacy of Eribulin Mesylate in Treating Adult Females With Locally Advanced or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Eribulin Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risperidone vs. Bupropion ER Augmentation of SSRIs in Treatment-Resistant Depression
Status: COMPLETED
Conditions: Unipolar Depression
Interventions: DRUG: Rispridone (drug) and Bupropion ER (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Smoking Cessation Program in the Construction Sector
Status: RECRUITING
Conditions: Smoking Cessation|Tobacco Use Cessation|Tobacco Smoking
Interventions: DRUG: Nicoderm C-Q Gum|BEHAVIORAL: Tobacco Quit-line|BEHAVIORAL: Brief Behavioral Counseling|BEHAVIORAL: Intensive Behavioral Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of rTMS Treatment After Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries|Myelopathy
Interventions: PROCEDURE: Repetitive transcranial magnetic stimulation (rTMS)|PROCEDURE: Placebo stimulation using a placebo coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: JUPITER Study: Transapical Aortic Valve Implantation for Aortic Regurgitation
Status: COMPLETED
Conditions: Aortic Stenosis|Aortic Insufficiency|Aortic Regurgitation
Interventions: DEVICE: Transcatheter aortic valve replacement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Trigeminal Nerve Blockade
Status: ENROLLING_BY_INVITATION
Conditions: Mouth Abnormalities|Cleft Palate|Birth Defect
Interventions: DRUG: Ropivacaine|OTHER: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Stroke With AMES + EMG Biofeedback
Status: COMPLETED
Conditions: Stroke|Plegia|Paresis|Cerebrovascular Accident
Interventions: DEVICE: AMES Therapy (assisted movement and enhanced sensation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MASTERMIND - Understanding Individual Variation in Treatment Response in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Gliclazide 80mg OD|DRUG: Sitagliptin 100mg OD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of CD19/BCMA Chimeric Antigen Receptor T Cells Therapy for Patients With Refractory Scleroderma
Status: RECRUITING
Conditions: Scleroderma|Autoimmune Diseases
Interventions: BIOLOGICAL: Assigned Interventions CD19/BCMA CAR T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Unidas Por Vida y Salud: Increasing Breast and Cervical Cancer Screening in El Paso
Status: COMPLETED
Conditions: Breast Cancer|Cervical Cancer
Interventions: BEHAVIORAL: Unidas por Vida y Salud prevention program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Safety and Efficacy of a Single Dose of UBX0101 in Patients With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: UBX0101|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Memantine in Adult Autism Spectrum Disorder
Status: TERMINATED
Conditions: Autism|Asperger's Disorder|Pervasive Developmental Disorder NOS
Interventions: DRUG: memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-Ethnic Study of Atherosclerosis (MESA) - Ancillary Eye Study
Status: COMPLETED
Conditions: Atherosclerosis|Cardiovascular Diseases|Coronary Arteriosclerosis|Coronary Disease|Cerebrovascular Disorders|Heart Failure, Congestive|Myocardial Infarction|Heart Diseases|Diabetes Mellitus, Non-insulin Dependent|Hypertension|Diabetic Retinopathy|Macular Degeneration|Diabetes Mellitus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Frequen-ZZZ SleepPad Investigational Device POC
Status: COMPLETED
Conditions: Insomnia|Sleep|Sleep Disturbance
Interventions: DEVICE: Activated Sleep Pad system (Frequen-ZZZ)|DEVICE: Deactivated Sleep Pad system (Frequen-ZZZ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Experimental Evaluation of a Program to Foster Socioemotional Competence of Children in Third Grade and Their Teachers
Status: NOT_YET_RECRUITING
Conditions: Social Skills|Emotion Regulation
Interventions: BEHAVIORAL: 10 minutes program|BEHAVIORAL: 1 hour PD program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Verify the Effectiveness rTMS Using MEG
Status: UNKNOWN
Conditions: Tinnitus
Interventions: DEVICE: 1|DEVICE: 2|DEVICE: 3|DEVICE: 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cobalt Alloy Pedicle Screw Implantation for Severe Kyphosis Deformity in Spinal Tuberculosis
Status: UNKNOWN
Conditions: Spinal Tuberculosis
Interventions: DEVICE: cobalt alloy pedicle screw implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doula Home Visiting Randomized Trial
Status: COMPLETED
Conditions: Breast Feeding|Parenting|Child Development|Depression, Postpartum
Interventions: BEHAVIORAL: Doula Home Visiting|BEHAVIORAL: Case management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Learn More About How Radium-223 Affects the Quality of Life of Colombian Patients With Prostate Cancer That Has Not Responded to Testosterone Lowering Treatment and Has Spread to the Bones, and to Better Understand Its Safety
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Radium-223-dichloride (Xofigo, BAY88-8223)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Pharmacokinetics of Patanase in Pediatric Patients 2 to < 6 Years of Age
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Olopatadine Hydrochloride Nasal Spray 0.6%|DRUG: Olopatadine Hydrochloride Nasal Spray Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE