pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clinical Study to Investigate the Tooth Stain Removal Efficacy of Two Experimental Toothpastes Compared to a Standard Toothpaste When Used Twice Daily for 8 Weeks
Status: COMPLETED
Conditions: Oral Hygiene
Interventions: DRUG: Experimental Dentifrice 1|DRUG: Experimental Dentifrice 2|DRUG: Reference Dentifrice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Elotuzumab in Autologous Stem Cell Transplantation (ASCT) and Lenalidomide Maintenance for Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Elotuzumab|DRUG: Lenalidomide|OTHER: autologous PBMC reconstitution|OTHER: ASCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Treatment by IM Ketamine to IV Ketamine in Patients With Renal Colic
Status: UNKNOWN
Conditions: Acute Pain|Renal Colic
Interventions: DRUG: IV Ketamine|DRUG: IM Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Enhanced Recovery After Lumber Laminectomy Using Epidural and General Anesthesia
Status: COMPLETED
Conditions: Postoperative Recovery|Epidural Blockade|Endotracheal Tube|Laminectomy
Interventions: PROCEDURE: (Epidural /GA using tolerable endotracheal tube (TET) group, group II|PROCEDURE: standard general anesthetic technique, control group, group I
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The ERA Test as a Diagnostic Guide for Personalized Embryo Transfer
Status: COMPLETED
Conditions: Endometrial Receptivity
Interventions: OTHER: personalized Embryo Transfer (pET)|OTHER: Frozen Embryo Transfer (FET)|OTHER: Fresh Embryo Transfer (ET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Impact of Ear Pain Anticipatory Guidance Counseling on Otitis Related Visits in a Low Income Population
Status: COMPLETED
Conditions: Otitis Media
Interventions: OTHER: ear pain counseling|OTHER: language power counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: tDCS in the Prevention of Relapse After Electroconvulsive Therapy
Status: TERMINATED
Conditions: Depression
Interventions: DEVICE: Device : Transcranial direct current stimulation|DEVICE: Device : sham Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: RIRS Versus ESWL for the Treatment of Renal Stones
Status: COMPLETED
Conditions: Renal Stones
Interventions: PROCEDURE: RIRS|PROCEDURE: ESWL|DEVICE: Rigid and flexible ureteroscope|DEVICE: Lithotripter|DEVICE: Holmium laser|DEVICE: Basket for fragment removal|PROCEDURE: General or spinal anesthesia|DRUG: Intravenous pain medication|DEVICE: X-ray|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab for High-Risk MDS/AML Patients After Allogeneic Stem Cell Transplant With Post-Transplant Cyclophosphamide
Status: WITHDRAWN
Conditions: Leukemia, Myeloid, Acute|Myelodysplastic Syndromes|Myelodysplastic Syndrome Acute Myeloid Leukemia
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Traditional Chinese Yijinjing Exercise on Hand Dysfunction in Rheumatoid Arthritis Patients
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|YiJinJing Exercise|Hand Function|Randomized Controlled Trial
Interventions: BEHAVIORAL: Yi Jin Jing exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Cluster-RCT to Increase the Uptake of LARCs Among Adolescent Females and Young Women in Cameroon.
Status: WITHDRAWN
Conditions: Contraception Behavior|Contraceptive Usage|Contraceptive Method Switching|Contraception
Interventions: BEHAVIORAL: Training|BEHAVIORAL: App|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of tDCS on Locomotion and Equilibrium in Hemiplegic Patients
Status: COMPLETED
Conditions: Gait Disorders
Interventions: DEVICE: anodal tDCS and sham tDCS stimulations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease With Qingkepingchuan Granules Clinical Observation of Phlegm-Heat and Lung Depletion
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Qingkepingchuan Granules|OTHER: conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Autologous, Adult Adipose-Derived Stem/Stromal Cells In Chronic Lung Disorders
Status: ENROLLING_BY_INVITATION
Conditions: Lung Disease
Interventions: PROCEDURE: lipoaspiration|PROCEDURE: ADcSVF|PROCEDURE: Normal Saline IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gong's Mobilization and Sustained Natural Apophyseal Glide in Office Workers With Cervical Spine Overload
Status: COMPLETED
Conditions: Cervical Spine Sprain
Interventions: OTHER: Gong's mobilization|OTHER: SNAG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexketoprofen Dosage According to Chronotherapy
Status: NOT_YET_RECRUITING
Conditions: Tooth, Impacted|Trismus|Pain|Inflammatory Response
Interventions: DRUG: Dexketoprofen 25 MG|DRUG: Dexketoprofen 25 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Second-line Treatment With CAdonilimab and LEnvatinib for Unresectable HCC
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Cadonilimab+Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of N-acetyl Cysteine, Acetyl L- Carnitine and Medicated Paraffin Oil in Aluminium Phosphide Poisoning
Status: UNKNOWN
Conditions: the Study Focus to Improve the Standard of Care Used for Aluminuim Phosphide Poisoning and to Save Patients With the Minimal Organ Damage
Interventions: DRUG: N-acetyl cysteine|DIETARY_SUPPLEMENT: acetyl L-carnitine|DRUG: medicated paraffin oil|DRUG: Sodium Bicarbonate Powder and ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of a Collagen Hemostatic Dressing After Tooth Extraction
Status: COMPLETED
Conditions: Tooth Avulsion
Interventions: DEVICE: Hemostatic dressing ETIK COLLAGENE|OTHER: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Human Chorionic Gonadotrophin in an Antagonist Protocol
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Low dose HCG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy Using Aminolevulinic Acid in Treating Patients With Oral Leukoplakia
Status: TERMINATED
Conditions: Oral Leukoplakia
Interventions: DRUG: aminolevulinic acid hydrochloride|DRUG: photodynamic therapy|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Methods for Anterior Cruciate Ligament Reconstruction
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Rupture|Deficiency of Anterior Cruciate Ligament|Chronic Instability of Knee|Anterior Cruciate Ligament Injury
Interventions: PROCEDURE: Patellar Tendon|PROCEDURE: Hamstring Tendon|PROCEDURE: Double-Bundle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: rTMS for Cognitive Rehabilitation After TBI
Status: COMPLETED
Conditions: Cognitive Impairment|Traumatic Brain Injury
Interventions: DEVICE: repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: the Antibacterial Effect of Zinc ,Silver and Fluoride
Status: UNKNOWN
Conditions: Dental Caries
Interventions: PROCEDURE: silver modified glass ionomer|PROCEDURE: zinc modified|PROCEDURE: conventional glass ionomer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Influence of PTH-lowering by Etelcalcetide (Parsabiv®) on the Calcification Propensity of Serum in Dialysis Patients
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DRUG: Etelcalcetide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Determine the Safety, Tolerability and Pharmacokinetics of UV-4B Solution Administered Orally in Healthy Subjects
Status: COMPLETED
Conditions: Viral Infection
Interventions: DRUG: UV-4B 3 mg|DRUG: UV-4B 10 mg|DRUG: UV-4B 30 mg|DRUG: UV-4B 90 mg|DRUG: UV-4B 180 mg|DRUG: UV-4B 360 mg|DRUG: UV-4B 720 mg|DRUG: UV-4B 1000 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The EndoGastric Solutions TEMPO Trial
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: DEVICE: EsophyX System with SerosaFuse fasteners|DRUG: PPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Trauma-Informed, Evidence-Informed Interventions for Latino Families Experiencing Domestic Violence
Status: COMPLETED
Conditions: Interpersonal Relations
Interventions: BEHAVIORAL: SafeCare+ (SC+)|BEHAVIORAL: SafeCare (SC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Confocal Laser Endomicroscopy for Brain Tumors
Status: TERMINATED
Conditions: Low Grade Glioma (LGG), High Grade Glioma (HGG)
Interventions: PROCEDURE: confocal endomicroscopy with the CELLVIZIO® system (Mauna Kea technology)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Promoting Sleep and Physical Activity Among Adolescent Psychiatric Patients
Status: NOT_YET_RECRUITING
Conditions: Mental Disorder in Adolescence|Insomnia|Delayed Sleep-Wake Phase Disorder
Interventions: BEHAVIORAL: SLEEPAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Replication of the P04334 Asthma Trial in Healthcare Claims Data
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Formoterol fumarate 10 mcg|DRUG: Mometasone furoate/formoterol fumarate combination MDI 200/10 mcg BID
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Probiotic on Modulation of the Intestinal Microbiota in Constipated Patients
Status: COMPLETED
Conditions: Intestinal Bacteria Flora Disturbance|Constipation
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Education Given to Prospective Fathers on Daily Care of the Baby and Father-Infant Attachment
Status: COMPLETED
Conditions: Pathernal Attachment|Effect of Education to Pathernal Attachment
Interventions: OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Mother-Baby Yoga and Baby Massage on Attachment and Sleep
Status: COMPLETED
Conditions: Newborn|Yoga|Mother-Infant Interaction|Sleep
Interventions: BEHAVIORAL: Baby Massage|BEHAVIORAL: Monther-Baby Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SiFi vs FNB Local Anesthesia for Hip Fracture Surgeries
Status: NOT_YET_RECRUITING
Conditions: Hip Fractures|Surgery|Anesthesia, Local
Interventions: PROCEDURE: Regional anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Movicol in Childhood Constipation (ProMotion Study)
Status: COMPLETED
Conditions: Feces, Impacted
Interventions: DRUG: Polyethylene glycol 3350 NA bicarbonate NaCl KCl (Movicol)|DRUG: Lactulose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Nifedipine and Enalapril in Medical Resources Used in the Postpartum Period
Status: COMPLETED
Conditions: Hypertension in Pregnancy|Preeclampsia Severe|Gestational Hypertension|Postpartum Preeclampsia|Postpartum
Interventions: DRUG: NIFEdipine ER|DRUG: Enalapril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Intra-Arterial Cisplatin With IV Thiosulfate in Patients With Lung Cancer or Lung Metastases
Status: COMPLETED
Conditions: Lung Neoplasms|Neoplasm Metastasis
Interventions: DRUG: Cisplatin, Thiosulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Fibrin and Autologous Fibrin Glue
Status: WITHDRAWN
Conditions: Gingival Recession
Interventions: OTHER: Group A - PRF plus AFG with a CAF|OTHER: Group B - PRF only with a CAF|OTHER: Group C - CTG with a CAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics Between Fixed-dose Combination VR 160/20 mg and Co-administration of Diovan® (Valsartan) Film-coated Tablet 160 mg and Crestor® (Rosuvastatin) 20 mg
Status: COMPLETED
Conditions: Hypertension|Hyperlipidemia
Interventions: DRUG: Sequence 1 : Period 1 (VR 160/20 mg-1), Period 2(VR 160/20 mg-2), Period (V+R)|DRUG: Sequence 2 : Period 1 (VR 160/20 mg-2), Period 2 (V+R), Period 3 (VR 160/20 mg-1)|DRUG: Sequence 3 : Period 1 (V+R), Period 2 (VR 160/20 mg-2), Period 3 (VR 160/20 mg-1)|DRUG: Sequence 4 : Period 1 (VR 160/20 mg-1), Period 2 (V+R), Period 3 (VR 160/20 mg-2 )|DRUG: Sequence 5 : Period 1 (VR 160/20 mg-2), Period 2 (VR 160/20 mg-1), Period 3 (V+R )|DRUG: Sequence 6 : Period 1 (V+R), Period 2 (VR 160/20 mg-1), Period 3 (VR 160/20 mg-2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Lifestyle Intervention on Cardiovascular Disease Risk Among Women
Status: COMPLETED
Conditions: Cardiovascular Risk Factor|Lifestyle Risk Reduction
Interventions: BEHAVIORAL: The letters with the Cochrane abstracts in the form of blog-shots|BEHAVIORAL: The letters with remainder on cardiovascular risk factors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Testing Atezolizumab With or Without Selinexor in Patients >= 18 Years Old With Alveolar Soft Part Sarcoma, the Axiom Study
Status: RECRUITING
Conditions: Advanced Alveolar Soft Part Sarcoma|Advanced Soft Tissue Sarcoma|Metastatic Alveolar Soft Part Sarcoma|Unresectable Alveolar Soft Part Sarcoma
Interventions: BIOLOGICAL: Atezolizumab|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Selinexor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trametinib + HDM201 in CRC Patients With RAS/RAF Mutant and TP53 Wild-type Advanced/Metastatic Colorectal Cancer Mutant and TP53 Wild-type
Status: COMPLETED
Conditions: Colorectal Cancer|Advanced Cancer|Metastatic Cancer
Interventions: DRUG: HDM201|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABBV-085, an Antibody Drug Conjugate, in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors|Undifferentiated Pleomorphic Sarcoma|Squamous Cell Carcinoma of the Head and Neck|Carcinoma of the Breast
Interventions: DRUG: ABBV-085
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Predictions of ETTcP With Pilot Balloon Palpation Among Anaesthesia Residents in Different Years
Status: UNKNOWN
Conditions: Endotracheal Tube Cuff Pressure
Interventions: BEHAVIORAL: pressure measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study to Assess the Safety and Effectiveness of Test Product in Healthy Adult Human Subjects Having Symptoms of Gut Dysbiosis (Heart Burn, Bloating, Constipation and Gut Immunity).
Status: NOT_YET_RECRUITING
Conditions: Gut Dysbiosis
Interventions: OTHER: MetProUltima
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Double-Blind, Double-Dummy, 2-Period Crossover of a 20-Minute Versus a 4-hour IV of MOA-728 in Stable Methadone Subjects
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: MOA-728
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Cadonilimab Combined With Gem/Cis as First Line Therapy in Patients With Advanced ICC
Status: ACTIVE_NOT_RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Cadonilimab+Gem/Cis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Symbiotic Use in Post-Bariatric Surgery Patients
Status: RECRUITING
Conditions: Bariatric Surgery Candidate
Interventions: DIETARY_SUPPLEMENT: Symbiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "The Effects of Oxytocin on Patients With Borderline Personality Disorder"
Status: COMPLETED
Conditions: Effects of Oxytocin on Borderline Personality Disorder|Borderline Personality Disorder
Interventions: DRUG: Oxytocin|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Identification of Predictive and Prognostic Markers for Lung Cancer With Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer|Primary Tumor|Metastases
Interventions: GENETIC: Genome analysis of tissue samples.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Uterine Artery Pulsatility Index and Materno Fetal Outcomes
Status: UNKNOWN
Conditions: Labor Complication
Interventions: RADIATION: normal PI|RADIATION: pathological PI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of the GenePOC CDiff Assay for the Detection of the Toxin B Gene From Toxigenic Clostridium Difficile Strains
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: DEVICE: Comparison between GenePOC PCR and Reference Method
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Ready to Use Therapeutic Food (RUTF) Supplement After an Episode of Malaria Falciparum on Weight
Status: COMPLETED
Conditions: Weight Loss|Weight Gain|Convalescence|Malaria
Interventions: DIETARY_SUPPLEMENT: RUTF (Plumpynut®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparative Efficacy of Novel Transcranial Random Noise Stimulation Versus Direct Current Stimulation on Augmenting Digital Mirror Therapy in Chronic Stroke
Status: NOT_YET_RECRUITING
Conditions: Transcranial Direct Current Stimulation (tDCS)|Transcranial Random Noise Stimulation (tRNS)
Interventions: DEVICE: tRNS|DEVICE: tDCS|DEVICE: sham stimulation|BEHAVIORAL: digital MT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcranial Direct Current Stimulation on the Apathy of Alzheimer's Disease
Status: COMPLETED
Conditions: Apathy|Alzheimer's Disease
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Busulfan and Fludarabine as Conditioning for Allogeneic Stem Cell Transplantation: a Pharmacokinetic Study
Status: UNKNOWN
Conditions: Hematologic Malignancy
Interventions: DRUG: intravenous busulfan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Megestrol Acetate or Levonorgestrel-Releasing Intrauterine System in Treating Patients With Atypical Endometrial Hyperplasia or Endometrial Cancer
Status: WITHDRAWN
Conditions: Atypical Endometrial Hyperplasia|Endometrial Adenocarcinoma|Recurrent Endometrial Carcinoma|Stage IA Endometrial Carcinoma|Stage IB Endometrial Carcinoma|Stage II Endometrial Carcinoma|Stage IIIA Endometrial Carcinoma|Stage IIIB Endometrial Carcinoma|Stage IIIC Endometrial Carcinoma|Stage IVA Endometrial Carcinoma|Stage IVB Endometrial Carcinoma
Interventions: DRUG: megestrol acetate|DEVICE: levonorgestrel-releasing intrauterine system|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combined Cryotherapy and Immunotherapy on Systemic T Cell Changes and Clinical Outcomes in Metastatic Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer Stage IV
Interventions: PROCEDURE: Bronchoscopic cryotherapy|DRUG: Pembrolizumab|DRUG: Platinum based chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transdermal Microneedle Lignocaine Delivery Versus EMLA Patch for Topical Analgesia Before Venepuncture Procedure To Adults in Clinical Setting
Status: NOT_YET_RECRUITING
Conditions: Glaucoma|Cataract
Interventions: COMBINATION_PRODUCT: Lignocaine-loaded maltose microneedle array patch|DRUG: EMLA 5% patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Efficacy and Safety of Different Doses of KVD824 for Prophylactic Treatment of HAE Type I or II
Status: TERMINATED
Conditions: Angioedema, Hereditary, Types I and II
Interventions: DRUG: KVD824|DRUG: Placebo to KVD824
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of VE800 and Nivolumab in Patients With Selected Types of Advanced or Metastatic Cancer
Status: COMPLETED
Conditions: Metastatic Cancer|Melanoma|Gastric Cancer|Gastroesophageal Junction Adenocarcinoma|Colorectal Cancer
Interventions: BIOLOGICAL: VE800|DRUG: Nivolumab|DRUG: Vancomycin Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Versus Standard Endoscopic Interventions for Peripancreatic Fluid Collections
Status: RECRUITING
Conditions: Acute Pancreatitis|Peripancreatic Fluid Collections|Endoscopic Ultrasound-Guided Drainage|Pancreatic Fluid Collections
Interventions: PROCEDURE: Early drainage of peripancreatic fluid collections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of a Novel Leuprolide With Market Leuprolide
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: Lutrate|DRUG: Enantone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/IIa Trial of Gemcitabine Plus Trastuzumab and Pertuzumab in Previously Treated Metastatic HER2+ Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Gemcitabine|DRUG: Trastuzumab|DRUG: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Mirror Therapy for Those With Acquired Brain Injury: A Clinical Pilot Study
Status: UNKNOWN
Conditions: Acquired Brain Injury Including Stroke
Interventions: DEVICE: Virtual Reality Mirror Therapy|PROCEDURE: Traditional Mirror Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Clinical Effects of Interferon Gamma-1b in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Interferon-gamma 1b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing High Blood Sugar in People Being Treated for Metastatic Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Breast Cancer Stage IV|Metastatic Breast Cancer
Interventions: DIETARY_SUPPLEMENT: Ketogenic Diet|DIETARY_SUPPLEMENT: Low Carbohydrate Diet|DRUG: Alpelisib|DRUG: Fulvestrant|DRUG: Canagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Assessing the HERV-W Env Antagonist GNbAC1 for Efficacy in MS
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: GNbAC1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metolazone As Early Add On Therapy For Acute Decompensated Heart Failure
Status: WITHDRAWN
Conditions: Acute Decompensated Heart Failure
Interventions: DRUG: Placebo|DRUG: Metolazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adapting Enhanced Recovery Programs for Low Health Literacy Patients
Status: NOT_YET_RECRUITING
Conditions: Surgery|Health Knowledge, Attitudes, Practice|Colorectal Disorders
Interventions: OTHER: Educational intervention (VISACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pazopanib in Combination With Capecitabine in Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Pazopanib plus capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triple DAAs Regimen in Treating Non-cirrhotic HCV GT1b Subjects
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection
Interventions: DRUG: LDV/SOF+ASV|DRUG: SOF+DCV+SMV|DRUG: SOF+DCV+ASV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Macular Photocoagulation Study (MPS)
Status: UNKNOWN
Conditions: Choroidal Neovascularization|Macular Degeneration|Histoplasmosis
Interventions: PROCEDURE: Argon Blue-Green Laser Photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of Sofosbuvir and Ledipasvir From Soviredia 90/400 mg Tablets (Minapharm, Egypt) Versus Harvoni 90/400 mg Tablets (Gilead Sciences, USA)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Soviredia|DRUG: Harvoni (first dose)|DRUG: Harvoni (Second dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Multi-session fMRI-Neurofeedback in PTSD
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder
Interventions: OTHER: MRI Biofeedback|OTHER: Sham-MRI Biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Sample Measurements and Physical Activity Levels in Type II Diabetes and/or COVID-19
Status: UNKNOWN
Conditions: Covid19|Diabetes Mellitus, Type 2
Interventions: DRUG: COVID-19 group (Group I)|DRUG: Type II Diabetes Mellitus and COVID-19 group (Group II)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Zephyrus II: Efficacy and Safety Study of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Pamrevlumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hormone Therapy in Preventing Endometrial Cancer in Patients With a Genetic Risk For Hereditary Nonpolyposis Colon Cancer
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: DRUG: medroxyprogesterone|DRUG: ethinyl estradiol|DRUG: norgestrel|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Cabazitaxel for Patients With Breast or Lung Cancer and Recurrent or Progressive Brain Metastases - Cabazitaxel for Brain Metastases (CaBaMet)
Status: TERMINATED
Conditions: Breast Cancer|Lung Cancer|Recurrent Brain Metastases|Progressive Brain Metastases
Interventions: DRUG: Cabazitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kidney Awareness Registry and Education
Status: COMPLETED
Conditions: Chronic Kidney Disease (CKD)
Interventions: BEHAVIORAL: CKD Registry|BEHAVIORAL: ATSM + Health Coach|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Effect of Increased Stomach pH on Evacetrapib in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Evacetrapib|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Genepro Generation 3 Protein Bioavailability Compared to Whey Protein
Status: UNKNOWN
Conditions: Absorption; Disorder, Protein|Protein Malabsorption|Protein Intolerance
Interventions: DIETARY_SUPPLEMENT: Genepro Generation 3 Protein|DIETARY_SUPPLEMENT: Whey Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: a Multicenter Clinical Trial for the Treatment of Children and Adolescents With Soft Tissue Sarcoma Stage 4
Status: COMPLETED
Conditions: Sarcoma, Soft Tissue
Interventions: DRUG: Topotecan|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Telerehabilitation in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: OTHER: Telerehabilitation|OTHER: Conventional Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liver Cirrhosis Network Cohort Study
Status: RECRUITING
Conditions: Cirrhosis|Cirrhosis, Liver|Cirrhosis Early|Cirrhosis Due to Hepatitis B|Cirrhosis Advanced|Cirrhosis Infectious|Cirrhosis Alcoholic|Cirrhosis, Biliary|Cirrhosis Cryptogenic|Cirrhosis Due to Hepatitis C|Cirrhosis Due to Primary Sclerosing Cholangitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Observation on the Effect of Auricular Acupoint Pressing on Insomnia and Adverse Events in MHD
Status: UNKNOWN
Conditions: Renal Dialysis|Sleep Initiation and Maintenance Disorders
Interventions: OTHER: Auricular point pressure therapy|DRUG: Oral estazolam medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbohydrates Under Target for Type 1 Diabetes Management
Status: WITHDRAWN
Conditions: Type 1 Diabetes
Interventions: OTHER: Insulin treatment optimization with participant's usual diet|DEVICE: Abbott's FreeStyle Libre|OTHER: Three-day food journal|OTHER: Medical visit|OTHER: Blood pressure measurements|OTHER: Anthropometric parameters measurements|OTHER: Indirect calorimetry test|OTHER: Well-being questionnaire|OTHER: Diet appreciation questionnaire|DEVICE: Pedometer (PiezoRxD)|OTHER: Hepatic imaging (MRI)|OTHER: Glucagon efficiency test|OTHER: Body composition : Dual Energy X-ray absorptiometry (DEXA)|OTHER: Blood tests|OTHER: Stool sample collections (optional)|OTHER: Hypoglycemia journal|OTHER: Ketone journal|OTHER: Adherence to the diet (Keenoa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Preoperative Myocardial Fibrosis Related to Mitral Valve Prolapse on Postoperative Left Ventricular Remodeling
Status: RECRUITING
Conditions: Regurgitation, Mitral
Interventions: OTHER: Cardiac Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase Ⅱ Study of Adductor Canal Block With HR18034 for Postsurgical Pain Management in TKA
Status: RECRUITING
Conditions: Postoperative Pain Management in Total Knee Arthroplasty
Interventions: DRUG: HR18034|DRUG: Ropivacaine Hydrochloride Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BG1805 Injection in the Treatment of Relapsed or Refractory Acute Myeloid Leukemia in Children
Status: NOT_YET_RECRUITING
Conditions: Leukemia|Acute Myeloid Leukemia
Interventions: BIOLOGICAL: BG1805
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin at Elective Cesarean Deliveries: A Dose-finding Study in Women With Twin Pregnancy
Status: COMPLETED
Conditions: Postpartum Hemorrhage|Twin
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effect of Pharmacokinetics/Pharmacodynamics (PK/PD) Interaction After co-Administration of Cilostazol With Ginkgo Biloba or Placebo
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cilostazol, Ginkgo biloba and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma
Status: RECRUITING
Conditions: Glioma, Malignant|Glioblastoma|Glioblastoma Multiforme|Glioblastoma Multiforme, Adult|High Grade Glioma|GBM|Brain Cancer
Interventions: PROCEDURE: Tissue autograft of pedicled temporoparietal fascial (TPF) or pericranial flap to bypass the blood brain barrier (BBB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decision Aid for Patients With Generalized Anxiety Disorder: Protocol for a Randomized Controlled Trial
Status: COMPLETED
Conditions: Generalized Anxiety Disorder|GAD
Interventions: OTHER: A web based-Patient Decision Aid (PtDA) (shown on the computer)|OTHER: A web-based fact sheet (one page shown on the computer) with general information on mental health as a part of usual care.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Individualized, Technological Interventions for Diabetes Care in the COVID-19 Ward
Status: TERMINATED
Conditions: Diabetes Mellitus|Covid19
Interventions: DEVICE: Continuous glucose monitoring (CGM, Dexcom G6)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of PTH(1-84) or Alendronate on Reduction of Back Pain in Postmenopausal Women With an Osteoporosis Related Vertebral Fracture(s) (FP-005-IM)
Status: TERMINATED
Conditions: Back Pain
Interventions: DRUG: Parathyroid hormone (PTH) (1-84)|DRUG: Alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Injection Pain and Local Tolerability Following Subcutaneous (SC) Administration of TV-46046
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: TV-46046|DRUG: Depo-subQ 104|DRUG: TV-46046 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Performance of the Hedrocel(R) Cervical Fusion Device
Status: COMPLETED
Conditions: Symptomatic Cervical Disc Disease
Interventions: DEVICE: Anterior Cervical Discectomy and Fusion|DEVICE: Anterior Cervical Discectomy and Fusion|DEVICE: Anterior Cervical Discectomy and Fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sit Less or Exercise More: Impact on Cardiometabolic Health in MS
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: Baseline activity (control regime)|OTHER: Increased sitting time (sit regime)|OTHER: Non-exercise physical activity (sit less regime)|OTHER: Structured exercise (exercise regime)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PD-L1 Antibody Combined With CTLA-4 Antibody for Patients With Advanced Intrahepatic Cholangiocarcinoma Who Progressed After Standard Treatment
Status: RECRUITING
Conditions: Cholangiocarcinoma, Intrahepatic|PD-L1|CTLA4
Interventions: DRUG: PD-L1 antibody combined with CTLA-4 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Value of ICG in Endometriosis
Status: COMPLETED
Conditions: Endometriosis|Laparoscopy|Near Infrared Fluorescence Imaging|Indocyanine Green (ICG)
Interventions: DRUG: Indocyanine Green
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mitomycin C in Patients With Incurable p16 Positive Oropharyngeal and p16 Negative Head and Neck Squamous Cell Carcinoma (HNSCC) Resistant to Standard Therapies
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma of the Head and Neck|Squamous Cell Carcinoma, Head and Neck
Interventions: DRUG: Mitomycin-C|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Brief Cognitive Intervention After Intrusive Memories of Trauma With Young Refugees
Status: COMPLETED
Conditions: Intrusive Memories of Trauma, Symptom of Post Traumatic Stress Disorder (Criterion B1)
Interventions: BEHAVIORAL: Brief cognitive intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ursodeoxycholic Acid in the Treatment of Intrahepatic Cholestasis of Pregnancy
Status: COMPLETED
Conditions: Intrahepatic Cholestasis|Pregnancy
Interventions: DRUG: ursodeoxycholic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and S-1 for Locally Advanced Unresectable or Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: S-1|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Airway Microbiome of Cystic Fibrosis Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Cystic Fibrosis
Interventions: BIOLOGICAL: Probiotic throat spray
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: First in Human (FIH) Study to Assess Safety and Efficacy of the CorNeat KPro for the Treatment of Corneal Blindness
Status: TERMINATED
Conditions: Corneal Disease|Corneal Opacity|Corneal Injuries
Interventions: DEVICE: CorNeat KPro
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Oral Condition and the Effect of Dental Treatment on Physical Parameters of Athletes
Status: UNKNOWN
Conditions: Periodontal Diseases|Inflammation Gum|Caries,Dental
Interventions: PROCEDURE: Dental Scaling|OTHER: Oral hygiene instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanical Opening Device Implantation Following Intravenous r-tPA for Recanalization in Acute Ischemic Stroke
Status: UNKNOWN
Conditions: Ischemic Cerebrovascular Accident
Interventions: DEVICE: JRecanTM blood FR device|DRUG: IV r-tPA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Anti-HIV Drugs on the Hepatitis C Virus (HCV) in Adults Infected With Both HCV and HIV
Status: COMPLETED
Conditions: Hepatitis C|HIV Infections
Interventions: DRUG: Efavirenz|DRUG: Emtricitabine/Tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coupled Inspiratory and Expiratory Muscle Training in Children With Bronchial Asthma
Status: COMPLETED
Conditions: Bronchial Asthma
Interventions: OTHER: Placebo respiratory muscle training|OTHER: Inspiratory muscle training|OTHER: Combined inspiratory and expiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Stroke of CArotid Artery Bifurcation Origin Treated With Use oF the MicronEt-covered CGUARD (SAFEGUARD-STROKE)
Status: RECRUITING
Conditions: Carotid Artery Stenosis|Acute Ischemic Stroke
Interventions: DEVICE: Thrombectomy and Stenting under neuroprotection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adjuvant Ovarian Suppression Plus Aromatase Inhibitor or Tamoxifen in Young Women
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Goserelin|DRUG: Tamoxifen|DRUG: Aromatase Inhibitors|DRUG: Leuprolide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of A Smartphone Application in Treating Non-Specific Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: BEHAVIORAL: Smartphone Full version application|BEHAVIORAL: Samartphone limited version application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT