pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Third Enhanced Control of Hypertension and Thrombectomy Stroke Domain Within ACT-GLOBAL Adaptive Platform Trial
Status: NOT_YET_RECRUITING
Conditions: Ischemic Stroke, Acute
Interventions: OTHER: Conservative SBP Control|OTHER: Moderate SBP Control|OTHER: Intensive SBP Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Local Anesthetic (0.25% Bupivacaine) for Pain Control in Pediatric Cardiac Catheterization
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Standard of Care|DRUG: Standard of Care plus bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intranasal Probiotic Treatment to Reduce Severity of Symptoms in COVID19 Infection
Status: COMPLETED
Conditions: COVID-19 Infection
Interventions: OTHER: Probiorinse|OTHER: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Computer-aided Diagnosis System (CADx) in the Early Detection of Gastric Cancer in France. Cancer in France.
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: PROCEDURE: Evaluation of the proportion of gastric neoplastic lesions detected by a computer-aided diagnosis system (CADx) compared with experienced endoscopists.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Methodology Issues in a Tailored Light Treatment for Persons With Dementia - Aim 2
Status: RECRUITING
Conditions: Alzheimer's Disease|Sleep Disturbance
Interventions: DEVICE: Active Lighting Intervention|DEVICE: Control Lighting Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety, Local Tolerability, PK and PD of LDE225 on Sporadic Superficial and Nodular Skin Basal Cell Carcinomas (sBCC)
Status: TERMINATED
Conditions: Sporadic Superficial and Nodular Skin Basal Cell Carcinomas
Interventions: DRUG: LDE225 0.75%|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Methoxyamine and Fludarabine Phosphate in Treating Patients With Relapsed or Refractory Hematologic Malignancies
Status: COMPLETED
Conditions: Adult Nasal Type Extranodal NK/T-cell Lymphoma|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Cutaneous B-cell Non-Hodgkin Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Hepatosplenic T-cell Lymphoma|Intraocular Lymphoma|Nodal Marginal Zone B-cell Lymphoma|Peripheral T-cell Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Multiple Myeloma|Relapsing Chronic Myelogenous Leukemia|Small Intestine Lymphoma|Splenic Marginal Zone Lymphoma|Stage III Chronic Lymphocytic Leukemia|Testicular Lymphoma|Waldenström Macroglobulinemia
Interventions: DRUG: fludarabine phosphate|DRUG: methoxyamine|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|GENETIC: western blotting|OTHER: mass spectrometry|GENETIC: DNA analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Niclosamide as Add-on Therapy to the Standard of Care Measures in COVID-19 Management
Status: UNKNOWN
Conditions: Covid-19|SARS Pneumonia
Interventions: DRUG: Niclosamide Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of AN2690 Topical Solution to Treat Onychomycosis of the Toenail
Status: COMPLETED
Conditions: Onychomycosis of Toenails
Interventions: DRUG: AN2690 Topical Solution, 5%|DRUG: Solution Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: rTMS in Chronic Poststroke Dysphagia
Status: UNKNOWN
Conditions: Deglutition Disorders
Interventions: DEVICE: repetitive transcranial magnetic stimulation(rTMS)|DEVICE: Intermittent Theta-burst Stimulation(iTBS)|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Facilitating Opioid Care Connections
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid Court Model|Medication to Treat Opioid Use Disorder|Opioid Use
Interventions: BEHAVIORAL: OCM-RISE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Itacitinib Pre-modulation in DLBCL Receiving CAR T Cell Therapy
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Itacitinib|BIOLOGICAL: Chimeric antigen receptor (CAR) T-cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Image-Based Quantitative Assessment of Acute Radiation-Induced Changes in Glioma
Status: TERMINATED
Conditions: Glioma
Interventions: RADIATION: Fractionated Radiation|DRUG: Temozolomide|DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Effectiveness of Ureteral DJ Stent With Magnet (Blackstar, Urotech) Removal Under Ultrasound Control
Status: COMPLETED
Conditions: Urolithiasis
Interventions: DEVICE: stent extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Nyxol Eye Drops as a Single Agent and With Adjunctive Low-Dose Pilocarpine Eye Drops in Subjects With Presbyopia
Status: COMPLETED
Conditions: Presbyopia
Interventions: DRUG: Phentolamine Opthalmic Solution 0.75%|OTHER: Placebo|DRUG: Low dose pilocarpine|OTHER: Low dose pilocarpine vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Menthol on Dyspnoea in COPD Patients
Status: COMPLETED
Conditions: Copd|Dyspnea|Lung Diseases
Interventions: OTHER: Test with Menthol|OTHER: Test with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Inhaled vs IV Opioid Dosing for the Initial Treatment of Severe Acute Pain in the Emergency Department
Status: UNKNOWN
Conditions: Pain, Acute|Emergencies|Morphine
Interventions: DRUG: inhaled titration of morphine chlorhydrate|DRUG: IV placebo|DEVICE: Inhaled placebo|DRUG: IV titration of morphine chlorhydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: XIENCE PRIME SV Everolimus Eluting Coronary Stent Japan Post Marketing Surveillance (XIENCE PRIME SV Japan PMS)
Status: COMPLETED
Conditions: Ischemic Heart Disease|Angina Pectoris|Coronary Artery Disease|Coronary Artery Occlusion|Myocardial Ischemia
Interventions: DEVICE: XIENCE PRIME SV Everolimus Eluting Coronary Stent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Medium-term Effects of Molecular Hydrogen on Metabolic Fitness in Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Molecular hydrogen|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Improved Diagnosis of Familial Hypercholesterolemia Across the Northland (ID-FH)
Status: RECRUITING
Conditions: Familial Hypercholesterolemia|Cholesterol, Elevated|Genetic Disease
Interventions: BEHAVIORAL: Motivational interview (MI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: DEB-TACE+HAIC vs. HAIC for Large HCC
Status: RECRUITING
Conditions: Unresectable Hepatocellular Carcinoma
Interventions: PROCEDURE: dTACE-HAIC|PROCEDURE: HAIC|DRUG: dTACE-HAIC protocol|DRUG: HAIC protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aggrenox Prevention of Access Stenosis
Status: COMPLETED
Conditions: Kidney Failure
Interventions: DRUG: Aggrenox|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Integrative Intervention Strategies for Binge Eating in Patients With Overweight or Obesity
Status: NOT_YET_RECRUITING
Conditions: Binge Eating|Overweight and Obesity
Interventions: BEHAVIORAL: treatment-as-usual|BEHAVIORAL: combined TAU and guided self-help|BEHAVIORAL: combined TAU, GSH, and biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About Whether BAY H006689 Causes an Allergic Reaction When Applied as a Topical Gel in Healthy Participants
Status: COMPLETED
Conditions: Pain|Healthy Volunteers
Interventions: DRUG: Naproxen (BAYH006689)|DRUG: Placebo Gel|DRUG: A solution of 0.9% Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Additional Effects of Joint Mobilization in Addition to Rocabado Exercises on Alleviating Trismus Following Third Molar Extraction
Status: ACTIVE_NOT_RECRUITING
Conditions: Trismus
Interventions: PROCEDURE: Electrotherapy|PROCEDURE: Rocabado exercises|PROCEDURE: Maitland oscillatory mobilizations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pioglitazone Study of Triglyceride Changes in Subjects With Type 2 Diabetes After Conversion From Rosiglitazone.
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using a Lay Health Worker Program to Increase Breast and Cervical Cancer Screening in Low-Income Hispanic Women
Status: COMPLETED
Conditions: Breast Cancer|Cervical Cancer
Interventions: BEHAVIORAL: CLS Intervention|BEHAVIORAL: No CLS intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Action Observation and Motor Imagery on Students' Ability to Locate Anatomical Locations: A Randomised Control Trial
Status: NOT_YET_RECRUITING
Conditions: Motor Imagery|Action Observation
Interventions: OTHER: Action Observation|OTHER: Motor Imagery|OTHER: Traditional Teaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bioequivalence Study of Etodolac Capsules USP 300 mg Under Fasting Condition
Status: COMPLETED
Conditions: Fasting
Interventions: DRUG: Etodolac Capsules USP 300 mg|DRUG: Etodolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decreasing Narcotics in Advanced Pelvic Surgery
Status: COMPLETED
Conditions: Narcotic Use|Pain|Constipation|Nausea
Interventions: DRUG: Celebrex|DRUG: Gabapentin|DRUG: IV acetaminophen|DRUG: oral acetaminophen|DRUG: oral ibuprofen|DRUG: percocet|DRUG: vicodin|DRUG: Oxycodone|DRUG: dilaudid|DRUG: Dexamethasone|DRUG: zofran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Appendectomy by Low Impact Laparoscopy vs Routine Laparoscopy : a Randomized Prospective Monocentric Trial
Status: COMPLETED
Conditions: Appendicitis|Appendectomy
Interventions: PROCEDURE: Conventional group|PROCEDURE: Low impact laparoscopy group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pirfenidone LP or Collagen-polyvinylpyrrolidone in COVID-19
Status: COMPLETED
Conditions: COVID 19
Interventions: DRUG: Collagen-polyvinylpyrrolidone|DRUG: Pirfenidone 1200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Gelatamp in Wound Healing After Teeth Extraction: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Wound Heal
Interventions: DRUG: Colloidal silver gelatin sponge|DRUG: Sterile gauze pack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of INCB013739 on Cortisone Reducing Enzyme Activity in Obese People Predisposed to Diabetes
Status: COMPLETED
Conditions: Insulin Resistance|Obesity
Interventions: DRUG: INCB13739
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Association of Urine BDNF and NGF With Lower Urinary System Parameters
Status: RECRUITING
Conditions: Benign Prostatic Hyperplasia With Outflow Obstruction|Lower Urinary Tract Obstructive Syndrome
Interventions: PROCEDURE: Holmium laser enucleation of the prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Optimal Remifentanil Ce for Preventing Severe Cough and Hyperdynamic Response During Tracheal Extubation
Status: COMPLETED
Conditions: Cough|Hypertension
Interventions: DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Innovative Training Program for Elderly in Need of Care Individuals
Status: COMPLETED
Conditions: Poor Performance Status|Muscle Weakness
Interventions: DEVICE: SR-WBV|DEVICE: Virtual Games (VG)|OTHER: SR-WBV|DEVICE: Aktiv Tramp (Swiss Frei AG, Switzerland)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Treatment With Pramipexole or Risperidone in Patients With Refractory Obsessive-compulsive Disorder (OCD)
Status: NOT_YET_RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: Pramipexole|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Application of the J-PET Scanner Prototype
Status: RECRUITING
Conditions: Prostate Cancer|Prostatic Hyperplasia|Prostatic Neoplasms|Prostate Cancer Metastatic|Neuroendocrine Tumors|Neuroendocrine Carcinoma
Interventions: DIAGNOSTIC_TEST: J-PET scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Atorvastatin on Myonecrosis
Status: TERMINATED
Conditions: Coronary Disease
Interventions: DRUG: Placebo Oral Tablet|DRUG: Atorvastatin 80mg|OTHER: Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stem Cell Fistula Plug in Cryptoglandular Perianal Fistulas (MSC-AFP)
Status: COMPLETED
Conditions: Perianal Fistula|Cryptoglandular Perianal Fistula
Interventions: DRUG: MSC-AFP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketogenic Diet for Obesity Hypoventilation Syndrome
Status: COMPLETED
Conditions: Obesity Hypoventilation Syndrome|Ketogenic Dieting|Hypercapnic Respiratory Failure
Interventions: DIETARY_SUPPLEMENT: Ketogenic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zonisamide/Bupropion Effects on Switching to Electronic Cigarettes
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Zonisamide|DRUG: Bupropion|OTHER: Halo G6 e-cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Colon Delivered Vitamin C on Gut Microbiota and Related Health Biomarkers in Healthy Older Adults
Status: COMPLETED
Conditions: Quality of Life
Interventions: DIETARY_SUPPLEMENT: Vitamin C|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pain, Sexual Dysfunction, and Depression in Hemodialysis Patients
Status: COMPLETED
Conditions: End Stage Renal Disease|Sexual Dysfunction, Physiological|Pain|Depression
Interventions: BEHAVIORAL: Symptom management nurse intervention|BEHAVIORAL: Feedback intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of VR-therapy on BPSD and QoL of Individuals With Dementia Admitted to Hospital
Status: TERMINATED
Conditions: Dementia|Delirium Superimposed on Dementia
Interventions: OTHER: VR-therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of IV Amantadine on Freezing of Gait (FOG) Resistant to Dopaminergic Therapy
Status: UNKNOWN
Conditions: Parkinson's Disease|Freezing of Gait
Interventions: DRUG: PK-Merz® 200mg/500ml inj(Amantadine) , Normal saline 500ml inj
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Revascularization Versus Medical Treatment in Patients With Ischemic Left Ventricular Dysfunction
Status: RECRUITING
Conditions: Heart Failure With Reduced Ejection Fraction|Ischemic Cardiomyopathy
Interventions: PROCEDURE: Percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Jitongning Tablet to Treat Spondyloarthritis
Status: COMPLETED
Conditions: Spondyloarthritis
Interventions: DRUG: Jitongning tablet(High-dose )|DRUG: Jitongning tablet(Low-dose )|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Safety, Tolerability, and Efficacy of Evenamide in Patients With Chronic Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Evenamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Outcomes for Quality of Life and Activities of Daily Living for BKP in the Treatment of VCFs
Status: COMPLETED
Conditions: Compression Fracture of Vertebral Body|Osteoporosis|Cancer
Interventions: DEVICE: Balloon kyphoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pathways to Improved Adolescent Mental Health in Conflict Affected Families
Status: ACTIVE_NOT_RECRUITING
Conditions: Mental Health Issue|Gender Equality
Interventions: BEHAVIORAL: Rabbits for Resilience (RFR) + HIKA|BEHAVIORAL: Rabbits for Resilience (RFR) only|BEHAVIORAL: HIKA Healthy Relationship Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study to Demonstrate Long-Term Efficacy and Safety of CT-P13 When Co-administered With Methotrexate in Patient With Rheumatoid Arthritis Who Were Treated With Infliximab (Remicade or CT-P13) in Study CT-P13 3.1
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A PhaseI Study of HL-085 Plus Vemurafenib in Solid Tumor With BRAF V600 Mutation
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: HL-085|DRUG: Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of CGM and Connected Pen in T2DM Treated With Multiple Daily Insulin Injections
Status: RECRUITING
Conditions: Type 2 Diabetes Treated With Insulin
Interventions: DEVICE: Continuous glucose monitoring and use of connected insulinpen for bolus insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heat Therapy in Patients With Type 2 Diabetes Mellitus
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 2|Insulin Resistance
Interventions: PROCEDURE: Passive heating|PROCEDURE: Thermoneutral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Esmolol on Oxygenation Index in Patients With Acute Respiratory Distress Syndrome
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome
Interventions: DRUG: Esmolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Evaluate the Microbiology, Safety and Tolerability of C16G2 Varnish and Strip in Adolescent and Adult Subjects
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: C16G2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Adalimumab vs. Conventional Immunosuppression for Uveitis Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Uveitis
Interventions: BIOLOGICAL: Adalimumab (ADA)|DRUG: Conventional immunosuppression (CON)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Evaluation of Radiofrequency Ablation in the Treatment of Relapsed Graves' Disease.
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed Graves' Disease|Thyroid; Functional Disturbance|Radiofrequency Ablation Treatment
Interventions: PROCEDURE: Radiofrequency ablation treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of AGN 203818 in Patients With Painful Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathy, Painful
Interventions: DRUG: AGN 203818|DRUG: AGN 203818|DRUG: AGN 203818|DRUG: placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Dopamine in Postural Tachycardia Syndrome
Status: COMPLETED
Conditions: Postural Tachycardia Syndrome|Orthostatic Intolerance
Interventions: DRUG: Carbidopa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Medico-economic Evaluation of Robot-assisted Laparoscopy Compared With Conventional Laparoscopy in Hysterectomy for Endometrial Cancer.
Status: NOT_YET_RECRUITING
Conditions: Hysterectomies for Low- or Intermediate-risk Endometrial Carcinoma
Interventions: PROCEDURE: Robot-assisted laparoscopy|PROCEDURE: conventional laparoscopy|OTHER: Prospective cohort study|OTHER: Retrospective cohort study|OTHER: information and consent|OTHER: randomization|OTHER: Collection of socio-demographic, clinical, biological, imaging and histopathological data, treatment decision, recurrence|OTHER: Surgical data collection|OTHER: Biological data collection|OTHER: Collection of histological data from the surgical specimen|OTHER: Phone calls|OTHER: Pain assessment|OTHER: Collect of data on non-reimbursed transport|OTHER: Collect of everyday help|OTHER: Collection of the business resumption date|OTHER: SF36 questionnaire|OTHER: Questionnaire EQ5D-5L|OTHER: FIGO Stadium|OTHER: Collection of treatments (analgesics and anticoagulants up to J42, complication-related treatments, etc.)|OTHER: Collection of adjuvant treatments|OTHER: Recording of any complications, emergency room visits/unscheduled consultations, additional work stoppages to the initial one|OTHER: Collection of data
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Real World Effectiveness of Eptinezumab in Participants With Migraine
Status: TERMINATED
Conditions: Migraine
Interventions: DRUG: Eptinezumab|DRUG: Erenumab|DRUG: Onabotulinumtoxin-A|DRUG: Fremanezumab|DRUG: Galcanezumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Obeticholic Acid in Patients With Moderately Severe Alcoholic Hepatitis (AH)
Status: TERMINATED
Conditions: Alcoholic Hepatitis
Interventions: DRUG: Placebo|DRUG: 10 mg Obeticholic Acid (OCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimization of the Bowel Preparation Regimen for the PillCam® COLON 2 Capsule Endoscopy Procedure
Status: COMPLETED
Conditions: Colorectal Cancer Screening
Interventions: DEVICE: PillCam® COLON 2 procedure-CONTROL|DRUG: Senna tablets|DRUG: PEG|DRUG: Metoclopramide|DRUG: Erythromycin|DRUG: SUPREP oral sulfate solution|DRUG: Bisacodyl|DRUG: SUPREP oral sulfate solution with Gastrografin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Median Sevoflurane Concentration for Hypotension Between Young and Elderlypatients: Adaptive Clinical Trial
Status: UNKNOWN
Conditions: Hypotension
Interventions: DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preventing Gastric Glitch With Prucalopride and Buspirone: N-of-1 Clinical Trial
Status: COMPLETED
Conditions: Dyspepsia
Interventions: DRUG: Prucalopride|DRUG: Buspirone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Aortic Laryngeal Rehabilitation Graft
Status: RECRUITING
Conditions: Laryngeal Cancer|Total Laryngectomy
Interventions: PROCEDURE: Total laryngectomy and reconstruction by stented aortic allograft (using human tissue and device).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Clopidogrel Dose Adjustment in Acute Coronary Syndrome Patients With High On-treatment Platelet Reactivity
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Clopidogrel dose adjustment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Here's the Buzz: Evaluating Pediatric Post Op Pain and Nausea Following Tonsillectomy Surgery
Status: WITHDRAWN
Conditions: Tonsillectomy
Interventions: DIETARY_SUPPLEMENT: Honey|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of an AEP on Patient's Knowledge Regarding Asthma Disease and Inhaler Technique: RCT
Status: COMPLETED
Conditions: Chronic Respiratory Disease
Interventions: OTHER: Asthma Education Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Self-screening of Cardiovascular Risk
Status: COMPLETED
Conditions: Risk Factor, Cardiovascular
Interventions: BEHAVIORAL: CV-screening-1 plus personalized|BEHAVIORAL: CV-screening-2 plus personalized|BEHAVIORAL: CV-screening-1 plus standard|BEHAVIORAL: CV-screening-2 plus standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effectiveness of the Selective Serotonin Reuptake Inhibitor,Citalopram (Cipralex), in Prurigo Nodularis
Status: UNKNOWN
Conditions: Prurigo Nodularis
Interventions: DRUG: citalopram (cipralex)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Midazolam Premedication on Opioid-induced Mask Ventilation Difficulty
Status: COMPLETED
Conditions: Anesthesia Complication
Interventions: DRUG: Midazolam|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bisphosphonate Therapy for Osteogenesis Imperfecta
Status: COMPLETED
Conditions: Osteogenesis Imperfecta|Osteoporosis|Paget Disease of Bone
Interventions: DRUG: Alendronate|DRUG: Pamidronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rhythmic-Based Training With Immersive Mirror Visual Feedback for Neuro-Rehabilitation
Status: RECRUITING
Conditions: Stroke|Rehabilitation|Virtual Reality|Mirror Movement Therapy
Interventions: DEVICE: Mirror therapy|DEVICE: Virtual reality-based mirror therapy with rhythmic skill training|OTHER: Task-oriented training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Paclitaxel and Carboplatin With IV Avastin Therapy in Patients With Carcinomas of Mullerian Origin
Status: UNKNOWN
Conditions: Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Avastin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Patients With Everolimus-eluting Stent Xience V® Implanted in the Treatment of Restenosis in Non-coated Metallic Stent (BMS In-stent Restenosis) During a 2 Year Clinical Follow-up Period
Status: COMPLETED
Conditions: Coronary Restenosis
Interventions: DEVICE: Xience V®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study Between Anterior and Posterior Pyelotomy in Transperitoneal Laparoscopic Pyelolithotomy
Status: COMPLETED
Conditions: Large Renal Stone
Interventions: PROCEDURE: traditional transperitoneal laparoscopic pyelolithotomy|PROCEDURE: modified transperitoneal laparoscopic pyelolithotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Tracheal Intubation Using the Totaltrack vs the Airtraq Laryngoscope in Routine Airway Management
Status: UNKNOWN
Conditions: Endotracheal Intubation
Interventions: DEVICE: Orotracheal intubation with Totaltrack|DEVICE: Orotracheal intubation with Airtraq
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Using Osseodensification Protocol
Status: COMPLETED
Conditions: Alveolar Bone Resorption
Interventions: PROCEDURE: Alveolar ridge wideninig via applying osseodensification protocol using densah burs|PROCEDURE: Alveolar ridge widening via hand osteotomes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Integrative Nursing Based Multimodal Interventions for Uncontrolled Hypertensives
Status: COMPLETED
Conditions: Uncontrolled Hypertension|Treatment Compliance|Behavior, Health|Nurse's Role
Interventions: OTHER: Integrative Nursing based Multimodal Interventions for Uncontrolled Hypertensives|OTHER: Ongoing treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Study of GS-5806 to Treat Respiratory Syncytial Virus (RSV)
Status: WITHDRAWN
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: GS-5806|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of a Novel Sound-based Treatment for Managing Distress Related to Tinnitus
Status: NOT_YET_RECRUITING
Conditions: Tinnitus
Interventions: BEHAVIORAL: White Noise|BEHAVIORAL: Music and Auditory Beat Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Arch Dimension and Inclination of the Upper and Lower Incisors Changes
Status: UNKNOWN
Conditions: Malocclusion, Angle Class I
Interventions: DEVICE: Carriere SLX® (Passive self-ligating braces)|DEVICE: Empower® (Interactive self-ligating braces)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjunct Photodynamic Therapy in Chronic Periodontitis Among Cigarette-smokers.
Status: COMPLETED
Conditions: Chronic Periodontitis|Smoking
Interventions: DEVICE: Photodynamic therapy|PROCEDURE: Scaling and root planing (SRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CBM588 Capsules in Combination With Nivolumab and Ipilimumab for the Treatment of Advanced Stage Kidney Cancer
Status: RECRUITING
Conditions: Advanced Clear Cell Renal Cell Carcinoma|Advanced Renal Cell Carcinoma|Advanced Sarcomatoid Renal Cell Carcinoma|Metastatic Clear Cell Renal Cell Carcinoma|Metastatic Renal Cell Carcinoma|Metastatic Sarcomatoid Renal Cell Carcinoma|Stage III Renal Cell Cancer AJCC v8|Stage IV Renal Cell Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|BIOLOGICAL: CBM588 Capsules|PROCEDURE: Computed Tomography|BIOLOGICAL: Ipilimumab|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF
Status: RECRUITING
Conditions: Transthyretin Amyloidosis|Heart Failure|Heart Failure, Diastolic|Amyloidosis
Interventions: DIAGNOSTIC_TEST: 99mTc-pyrophosphate Scintigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Two Different Treatments 24 vs 48 Weeks Chronic Hepatitis C Genotypes 2 and/or 3 in co-Infected HIV-HCV
Status: UNKNOWN
Conditions: Chronic Hepatitis C|Co-Infection HIV-HCV
Interventions: DRUG: Peg interferon + Ribavirin|DRUG: Peg interferon + Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Venous Thromboembolism (VTE) With Either Rivaroxaban or Current Standard of Care Therapy
Status: COMPLETED
Conditions: Deep Vein Thrombosis (DVT)|Pulmonary Embolism (PE)
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Recommended VTE pharmacological treatments according to international guidelines
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Pre-operative Single Dose Antibiotic Prophylaxis on the Post-operative Implant Success
Status: RECRUITING
Conditions: Tooth Loss
Interventions: PROCEDURE: Dental implant placement|DRUG: Antibiotic prophylaxis|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Operative Versus Non-operative Treatment of Recalcitrant Plantar Fasciitis - A Randomized Study
Status: WITHDRAWN
Conditions: Plantar Fascitis|Surgical Treatment|Non-operative Treatment|Randomized Study
Interventions: PROCEDURE: Open plantar fasciotomy|OTHER: Conservative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Extension Study With Benralizumab for Asthmatic Adults on Inhaled Corticosteroid Plus Long-acting β2 Agonist
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: Benralizumab|BIOLOGICAL: Benralizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders
Status: RECRUITING
Conditions: Bipolar Disorder|Cannabis Use|Schizoaffective Disorder, Bipolar Type|Bipolar I Disorder|Bipolar II Disorder|Cannabis Use Disorder, Mild|Cannabis Use Disorder, Moderate|Cannabis Use Disorder, Severe
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Behavioral Modification to Prevent Congenital Cytomegalovirus
Status: COMPLETED
Conditions: Cytomegalovirus Infections|Pregnancy|Behavior
Interventions: BEHAVIORAL: Educational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of an Infant Formula With Milkfat and Prebiotics
Status: COMPLETED
Conditions: Infections|Stool Flora|Stool Biochemistry|Constipation|Food Intolerance
Interventions: DIETARY_SUPPLEMENT: new infant formula with prebiotics and beta-palmitate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Brazilian and Italian Evaluation of Safety Using Tacrolimus-eluting Stent With Short-term Dual Antiplatelet Regimen
Status: TERMINATED
Conditions: Stable Coronary Disease|Unstable Coronary Disease|Documented Silent Ischemia
Interventions: DEVICE: Drug Eluting Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Stem Cell Transplantation in Treating Patients With Metastatic or Recurrent Kidney Cancer
Status: WITHDRAWN
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: fludarabine phosphate|DRUG: mycophenolate mofetil|DRUG: tacrolimus|DRUG: thalidomide|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing a Comprehensive Handoff Program to Improve Pediatric Patient Safety
Status: COMPLETED
Conditions: Patient Safety|Resident Workflow|Resident Experience
Interventions: OTHER: Computerized handoff tool|OTHER: Team training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Validation of the Relationship Between Oxygenation Parameters and ORI™, in Mechanically Ventilated ICU Patients
Status: COMPLETED
Conditions: Intubation|Mechanical Ventilation|Intensive Care Unit
Interventions: PROCEDURE: Stepwise modifications of FiO2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Study of CAR-CLD18 T Cells in Patients With Advanced Gastric Adenocarcinoma and Pancreatic Adenocarcinoma
Status: UNKNOWN
Conditions: Advanced Gastric Adenocarcinoma|Pancreatic Adenocarcinoma
Interventions: GENETIC: CAR-CLD18 T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Efficacy of Taclonex Topical Suspension as a Supplement to Non-biologic Systemic Therapy
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Taclonex Topical Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Laropiprant (MK-0524) in Participants With Moderate to Severe Erythematotelangiectatic Rosacea (MK-0524-155)
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: Laropiprant|DRUG: Placebo for Laropiprant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase III Clinical Trial of TRAVATAN Z in Ocular Surface Health
Status: COMPLETED
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Travoprost ophthalmic solution 0.004% with SofZia® preservative system (TRAVATAN Z®)|DRUG: Latanoprost ophthalmic solution 0.005% (XALATAN®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cap-assisted Esophagogastroduodenoscopy on Observation of Major Duodenal Papilla
Status: COMPLETED
Conditions: Observation of Major Duodenal Papilla (MDP)
Interventions: DEVICE: Cap-EGD|DEVICE: Duo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Integrated Mental Health Care and Vocational Rehabilitation to Individuals on Sick Leave Due to Stress Disorders
Status: COMPLETED
Conditions: Adjustment Disorder|Burnout|Psychological Stress
Interventions: BEHAVIORAL: IBBIS mental health care and standard vocational rehabilitation|BEHAVIORAL: Integrated mental health care and vocational rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Walking Training in Peripheral Artery Disease (GrEnADa Sub-study)
Status: WITHDRAWN
Conditions: Peripheral Artery Disease|Intermittent Claudication
Interventions: OTHER: Stretching exercise group|OTHER: Walking training group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Natural Matrix Protein™ (NMP™) Fibers in Cervical and Lumbar Interbody Fusion
Status: NOT_YET_RECRUITING
Conditions: Degenerative Disc Disease|Degenerative Spondylolisthesis|Spinal Stenosis
Interventions: BIOLOGICAL: Natural Matrix Protein (NMP) Fibers|PROCEDURE: Lumbar interbody fusion|PROCEDURE: Cervical interbody fusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects on Metabolism and Cognitive Functions of a Commonly Used Commercial Food Supplement
Status: COMPLETED
Conditions: Postprandial Blood Glucose Regulation
Interventions: DIETARY_SUPPLEMENT: Panax ginseng|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Rotablation vs Intravascular Lithotripsy in Calcified Coronary Lesions
Status: UNKNOWN
Conditions: Coronary Artery Disease|Calcification
Interventions: DEVICE: Intravascular Lithotripsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Pharmacological Therapies for Pregnant Smokers
Status: TERMINATED
Conditions: Smoking|Pregnancy
Interventions: BEHAVIORAL: Motivational interviewing for smoking cessation|BEHAVIORAL: Cognitive behaviors therapy|DRUG: CBT + NRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Crushed Elbasvir/Grazoprevir Compared to the Whole Tablet
Status: COMPLETED
Conditions: Hepatitis C|Deglutition Disorders
Interventions: DRUG: Zepatier whole tablet|DRUG: Zepatier crushed tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT