pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Rituximab and Combination Chemotherapy in Treating Patients With Newly Diagnosed, HIV-Associated Burkitt's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim|BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: ifosfamide|DRUG: leucovorin calcium|DRUG: liposomal cytarabine|DRUG: methotrexate|DRUG: therapeutic hydrocortisone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Underbody and Overbody Forced Air Blanket in Pediatric Patients Undergoing Cardiovascular Interventions
Status: RECRUITING
Conditions: Hypothermia; Anesthesia
Interventions: OTHER: overbody blanket|OTHER: underbody blanket
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effectiveness of Exercise Program in Improving Quality of Life in Patients With Gastric Cancer Undergoing Gastrectomy
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: BEHAVIORAL: exercise group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effectiveness of the Neutropenic Diet in Pediatric Oncology Patients
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Acute Myelogenous Leukemia|Non-Hodgkins Lymphoma|Sarcoma|Neuroblastoma
Interventions: OTHER: Food Safety Guidelines|OTHER: Neutropenic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Evaluation of Clopidogrel Sulfate in Patients With Stable Angina/Old Myocardial Infarction to Whom Percutaneous Coronary Intervention is Being Planned
Status: COMPLETED
Conditions: Stable Angina|Myocardial Infarction
Interventions: DRUG: clopidogrel (SR25990)|DRUG: ticlopidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Ubiquinone and Combined Antioxidant Therapy in Non-proliferative Diabetic Retinopathy
Status: COMPLETED
Conditions: Non-proliferative Diabetic Retinopathy|Diabetes Mellitus Type 2
Interventions: DRUG: Ubiquinone|DRUG: Combined antioxidant therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Initial Feasibility of Using the Neurolyser XR Device for the Treatment of Axial Chronic Low Back Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Facet Syndrome of Lumbar Spine
Interventions: DEVICE: Neurolyser XR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of BFR Interventions in Healthy Individuals and Individuals With COPD
Status: RECRUITING
Conditions: Healthy|COPD
Interventions: OTHER: BFR during training|OTHER: BFR during rest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preoperative Ultra-hypofractionated Radiotherapy Followed by Surgery for Retroperitoneal Sarcoma
Status: RECRUITING
Conditions: Soft Tissue Sarcoma|Retroperitoneal Sarcoma|Radiotherapy Side Effect|Ultra-hypofractionated Radiotherapy|Stereotactic Ablative Radiotherapy
Interventions: RADIATION: ultra-hypofractionated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health Promotion and Wellness Program for Adults With Disabling Conditions
Status: COMPLETED
Conditions: Stroke|Multiple Sclerosis|Rheumatoid Arthritis
Interventions: BEHAVIORAL: SystemCHANGE Group Lifestyle counseling|BEHAVIORAL: Phone Lifestyle Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Predicting Arrhythmogenic Risk in Congenital Heart Patients: the PRECISION Study
Status: TERMINATED
Conditions: Arrhythmia in Children|Congenital Heart Disease
Interventions: DIAGNOSTIC_TEST: Provocative electrophysiology study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Management Of Placenta Previa Cases And Determination Of Hospitalization Criteria
Status: COMPLETED
Conditions: Placenta Previa
Interventions: DIAGNOSTIC_TEST: Vaginal Ultrasonography|DIAGNOSTIC_TEST: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparing Voiding Trials After Midurethral Sling for Stress Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence|Urethral Hypermobility|Cystocele
Interventions: OTHER: Voiding trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Increased Central Serotonergic Activity on Information Processing
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Escitalopram|DRUG: escitaolpram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Association Between Luminal Bile Salt Content and Duodenal Mucosal Integrity in Functional Dyspepsia
Status: COMPLETED
Conditions: Functional Dyspepsia
Interventions: PROCEDURE: Duodenogastroscopy|DEVICE: Duodenal aspiration catheter|DIETARY_SUPPLEMENT: Nutri drink
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Influence of Antibiotic Prophylaxis on Intraoperative Prosthetic Joint Infection Cultures
Status: COMPLETED
Conditions: Prosthetic Joint Infection
Interventions: DRUG: Cefazolin|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of Gantenerumab in Participants at Risk for or at the Earliest Stages of Alzheimer's Disease (AD)
Status: TERMINATED
Conditions: Alzheimers Disease
Interventions: DRUG: Gantenerumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 3D Instrumentation Versus Rotary Instrumentation
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DEVICE: XP-endo Shaper|DEVICE: iRace files
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S1827 (MAVERICK) Testing Whether the Use of Brain Scans Alone Instead of Brain Scans Plus Preventive Brain Radiation Affects Lifespan in Patients With Small Cell Lung Cancer
Status: RECRUITING
Conditions: Extensive Stage Lung Small Cell Carcinoma|Limited Stage Lung Small Cell Carcinoma|Lung Small Cell Carcinoma
Interventions: PROCEDURE: Magnetic Resonance Imaging|RADIATION: Prophylactic Cranial Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of an Optimised Monitored Anesthesia on the Patients' Recovery After Cytoreduction Surgery Plus HIPEC
Status: TERMINATED
Conditions: Hyperthermia|Colorectal Neoplasms|Oxaliplatin
Interventions: DRUG: Remifentanil infusion, desflurane titration and fluid infusion will be guided by NOL index, BIS index and Flotrac EV1000 system respectively|DRUG: Remifentanil infusion and desflurane titration will be guided by anesthesia usual practices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Dose-Escalation Study to Assess the Safety and Tolerability of LX214 Ophthalmic Solution in Healthy Volunteers, Followed by an Open-Label Evaluation of LX214 in Patients With Keratoconjunctivitis Sicca (KCS)
Status: COMPLETED
Conditions: Keratoconjunctivitis Sicca
Interventions: DRUG: voclosporin ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO5093151 in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT).
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Latanoprost|DRUG: Placebo|DRUG: RO5093151
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-marketing Study of Monteplase ("Cleactor") in Patients With Acute Pulmonary Embolism
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: DRUG: Monteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conventional Versus Intentional StraTegy in Lesions With High Risk PrEdiction of Side Branch OccLusion in InterVEntion
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Conventional Strategy|PROCEDURE: Intentional strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Taurolidine in Treating Patients With Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: chemotherapy|DRUG: taurolidine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Spices on Pathways Associated With Glucose Homeostasis and Inflammation on PBMCs of Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Fat challenge breakfast|OTHER: Fat challenge breakfast+spices|OTHER: Carbohydrate challenge breakfast|OTHER: Carbohydrate challenge breakfast+spices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectivity and Safety of PFO Closure vs Medicine in Alleviating Migraine
Status: RECRUITING
Conditions: PFO - Patent Foramen Ovale|Migraine
Interventions: DEVICE: PFO closure device|DRUG: Aspirin and clopidogrel|DRUG: Triptans
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Inhaled Fluticasone Furoate on Short-term Growth in Paediatric Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone furoate|DRUG: Placebo|DRUG: Salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Hydrogel Dressings and Ocular Lubricants in the Prevention on Corneal Damage in the Critically Ill
Status: COMPLETED
Conditions: Keratitis
Interventions: OTHER: Hydrogel dressing|OTHER: Lacrilube ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: A Single-Arm, Open, Exploratory Clinical Study of Pemigatinib in the Treatment of HER2-negative Advanced Breast Cancer Patients With FGFR Alterations
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Pemigatinib Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Red Yeast Rice Based Nutraceutical Plus Probiotic in Patients With Moderate Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Lactoflorene colesterolo|DIETARY_SUPPLEMENT: Placebo lactoflorene colesterolo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study Investigating the Combination of RAD001, Cetuximab and Irinotecan as Second-line Therapy After FOLFOX (or XELOX) Plus Bevacizumab in Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Carcinoma|Colorectal Tumors|Neoplasms, Colorectal
Interventions: DRUG: RAD001, Cetuximab, Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Viekira Pak or Mavyret Treatment for Patient With Chronic Kidney Disease and Hepatitis C
Status: COMPLETED
Conditions: Chronic Kidney Disease|Chronic Hepatitis C
Interventions: DRUG: Viekira Pak ± ribavirin|DRUG: Mavyret
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Transcutaneous Electrical Stimulation Garment Improve Gait in Children With Cerebral Palsy?
Status: UNKNOWN
Conditions: Cerebral Palsy|Spasticity, Muscle
Interventions: DEVICE: Mollii suit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Finding, Safety and Efficacy Study of RX-0201 Plus Everolimus in Metastatic Renal Cell Cancer
Status: TERMINATED
Conditions: Metastatic Renal Cell Cancer
Interventions: DRUG: RX-0201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: HNSCC|Lip SCC|Oral Cavity Cancer|Oropharynx Cancer|Larynx Cancer|Hypopharynx Cancer|Nasopharynx Cancer|Sinonasal Carcinoma|Cutaneous Squamous Cell Carcinoma|Head and Neck Neoplasms|Head and Neck Cancer|Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Pembrolizumab, Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gluten Related Disorders in Barrett's Esophagus
Status: UNKNOWN
Conditions: Celiac Disease|Barrett Esophagus|Gluten Sensitivity|GERD
Interventions: OTHER: Gluten free diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: ASIA Down Syndrome Acute Lymphoblastic Leukemia 2016
Status: RECRUITING
Conditions: Down Syndrome|Acute Lymphoblastic Leukemia|Childhood Cancer
Interventions: DRUG: Daunorubicin|DRUG: Prednisolone|DRUG: Vincristine|DRUG: Epirubicin|DRUG: E-coli L-asparaginase|DRUG: 6-Mercaptopurine|DRUG: Methotrexate|DRUG: Hydrocortisone|DRUG: Cytarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Establishing Best Treatment Strategy for T4 Esophageal Cancer
Status: RECRUITING
Conditions: Esophageal Cancer TNM Staging Primary Tumor (T) T4
Interventions: COMBINATION_PRODUCT: "Docetaxel", "Cisplatin", "fluorouracil", "Radiation"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Infectivity, Safety, and Immunogenicity of a Single Dose of a Recombinant Live-Attenuated Respiratory Syncytial Virus Vaccine (D46/NS2/N/ΔM2-2-HindIII) in RSV-Seronegative Infants 6 to 24 Months of Age
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: D46/NS2/N/ΔM2-2-HindIII|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Early TIPS in Patients With Liver Cirrhosis and Ascites
Status: NOT_YET_RECRUITING
Conditions: Liver Cirrhosis|Ascites Hepatic|Portal Hypertension
Interventions: PROCEDURE: Transjugular intrahepatic portosystemic shunt (TIPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Mediterranean Diet Nutrition Education Program for the Reduction of Cardiovascular Disease Risk in the Southeastern U.S.
Status: COMPLETED
Conditions: Cardiovascular Diseases|Cardiovascular Risk Factor|Obesity
Interventions: BEHAVIORAL: Mediterranean diet|DIETARY_SUPPLEMENT: Olive oil and mixed nuts|BEHAVIORAL: American Heart Association
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chlorhexidine to Prevent Catheter-related Urinary Tract Infection
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: OTHER: Long Intervention|OTHER: Mid-length Intervention|OTHER: Short Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multiple Dose Trial of Anti-glycation Agent GLY-230 in Healthy and Diabetic Subjects
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: GLY-230|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparison Study to Evaluate the Pharmacokinetics and Safety of NK-104-CR in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: A: NK-104-CR 8 mg|DRUG: B: Pitavastatin IR 4 mg|DRUG: C: Pitavastatin IR 8 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Patient Specific Implant Versus Miniplates for Advancement of Hypoplastic Maxilla
Status: NOT_YET_RECRUITING
Conditions: Cleft Lip and Palate
Interventions: DEVICE: PSI|DEVICE: Conventional miniplates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CRyoAblation vs AntiaRrhythmic Drugs for Persistent Atrial Fibrillation Trial
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DEVICE: Arctic Front Advance® balloon catheter|DRUG: Antiarrhythmic drug|DEVICE: Confirm RX heart monitor® (Abbott)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HNFO With or Without Helmet NIV for Oxygenation Support in Acute Respiratory Failure Pilot RCT
Status: RECRUITING
Conditions: Acute Hypoxemic Respiratory Failure
Interventions: DEVICE: Helmet Non-Invasive Ventilation (HNIV)|DEVICE: High Flow Nasal Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerance and Compliance of a High Caloric, High Protein Oral Nutritional Supplement - Free Intake
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: High caloric, high protein ONS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Clinical and Microbial Efficacy and Safety of AzaSite Compared to Vehicle for Bacterial Conjunctivitis (C-01-401-003)
Status: COMPLETED
Conditions: Bacterial Conjunctivitis
Interventions: DRUG: AzaSite|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: mHealth Intervention to Reduce Perceived Stress in Patients With Ischemic Heart Disease
Status: NOT_YET_RECRUITING
Conditions: Ischemic Heart Disease
Interventions: DEVICE: mindfulHeart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Treatment for Orthopaedic Post-operative Pain With Dexketoprofen Trometamol and Tramadol Hydrochloride
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Placebo|DRUG: Tramadol-single dose|DRUG: Dexketoprofen-single dose|DRUG: Dexketoprofen/Tramadol-single dose|DRUG: Tramadol-multiple doses|DRUG: Dexketoprofen-multiple doses|DRUG: Dexketoprofen/Tramadol-multiple doses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SPECTAlung: Screening Patients With Thoracic Tumors for Efficient Clinical Trial Access
Status: COMPLETED
Conditions: Any Stage of Lung Cancer (Any Histotype)|Any Stage of Malignant Pleural Mesothelioma|Any Stage of Any Thymic Malignancy
Interventions: GENETIC: Tumour markers testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Laparoscopic Endoscopic Cooperative Surgery in the Treatment of Gastric Stromal Tumors
Status: UNKNOWN
Conditions: Gastrointestinal Stromal Tumors
Interventions: PROCEDURE: laparoscopic and endoscopic cooperative surgery|PROCEDURE: laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Expanded Access Program for AM0010 (Pegilodecakin)
Status: NO_LONGER_AVAILABLE
Conditions: Melanoma|Prostate Cancer|Ovarian Cancer|Renal Cell Carcinoma|Colorectal Carcinoma|Pancreatic Carcinoma|Non-small Cell Lung Carcinoma|Solid Tumors|Breast Cancer
Interventions: BIOLOGICAL: AM0010
Study Type: EXPANDED_ACCESS
Clinical trial: Telemedical Coaching for Weight Loss
Status: COMPLETED
Conditions: Overweight|Obesity|Metabolic Syndrome
Interventions: DEVICE: telemedical (TM) group|BEHAVIORAL: telemedical coaching (TMC) group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of AMG 340 in Subjects With Metastatic Castrate-Resistant Prostate Carcinoma
Status: COMPLETED
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: AMG 340
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid Amniotic Fluid (AF) Test and a Non-Invasive Vaginal Fluid (VF) Test
Status: WITHDRAWN
Conditions: Intra-Amniotic Infection of Foetus
Interventions: DIAGNOSTIC_TEST: Perilynx Analyzer to measure AF and VF fluid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dual Task Training On Children With Ataxia After Medulloblastoma Resection
Status: COMPLETED
Conditions: Medulloblastoma, Childhood|Childhood Cancer
Interventions: BEHAVIORAL: Dual Task Training Program Group|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Characterize the Pharmacokinetics and Effect of Food on JNJ-31001074 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy|Pharmacokinetics
Interventions: DRUG: JNJ-31001074
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Lurbinectedin With or Without Irinotecan in Treating Patients With Relapsed or High Risk Metastatic Ewing Sarcoma
Status: WITHDRAWN
Conditions: Metastatic Ewing Sarcoma|Recurrent Ewing Sarcoma
Interventions: PROCEDURE: Fine-Needle Aspiration|DRUG: Irinotecan|DRUG: Irinotecan Hydrochloride|DRUG: Lurbinectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combining Manual Soft Tissue Release and Exercise Training in COPD: the Effect on LF, EC, and CAF
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Manual Soft Tissue Release|Exercise Training|Lung Function|Exercise Capacity|Cardiac Autonomic Function
Interventions: BEHAVIORAL: Manual soft tissue release|BEHAVIORAL: Myofascial release|BEHAVIORAL: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LAAS (Losartan Anti-Atherosclerosis Study)(0954-330)(COMPLETED)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: losartan potassium|DRUG: Comparator: carvedilol|DRUG: Comparator: losartan (+) hydrochlorothiazide (HCTZ)|DRUG: Comparator: carvedilol (+) hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of GC012F, a CAR T Therapy Targeting CD19 and BCMA in Subjects With Relapsed/Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Relapsed/ Refractory Multiple Myeloma
Interventions: BIOLOGICAL: GC012F
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Right-sided Retroflexion With Standard Adult Versus Pediatric Colonoscopes
Status: WITHDRAWN
Conditions: Colonic Neoplasms
Interventions: PROCEDURE: Retroflexion with the adult colonoscope.|PROCEDURE: Retroflexion with the pediatric colonoscope.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Haplo HCT vs Haplo-cord HCT for Patients With AML
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplantation|Haplo-identical Donor|Cord Blood Unit|Acute Myeloid Leukemia
Interventions: PROCEDURE: haplo-HCT|PROCEDURE: haplo-cord HCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BTX-1188 in Subjects With Advanced Malignancies
Status: TERMINATED
Conditions: Advanced Solid Tumor|Non Hodgkin Lymphoma|Acute Myeloid Leukemia
Interventions: DRUG: BTX-1188
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Genicular Nerves Block
Status: ACTIVE_NOT_RECRUITING
Conditions: Genicular Nerve Block for Pain in ACL Arthroscopy
Interventions: PROCEDURE: Genicular Nerves Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Pre-emptive Intravenous Morphine for Acute Post-craniotomy Pain.
Status: RECRUITING
Conditions: Pain, Postoperative|Anesthesia|Analgesia
Interventions: DRUG: Morphine|DRUG: Nacl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Biophoton Generator on Chronic-Stroke Patients' Recovery
Status: COMPLETED
Conditions: Chronic Stroke|Paralysis
Interventions: DEVICE: Active Biophoton Generators|DEVICE: Inactive Biophoton Generators
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Effectiveness of Home-based Programs for Preschool Children With Developmental Delay
Status: COMPLETED
Conditions: Developmental Delay
Interventions: BEHAVIORAL: professional therapists delivering the PHPA|BEHAVIORAL: parents executing the PHPA|BEHAVIORAL: health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Self-care Educational Program Via Telerehabilitation in Caregivers
Status: NOT_YET_RECRUITING
Conditions: Quality of Life
Interventions: OTHER: Telerehabilitation|OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of a Multiple-Action Tear Substitute (TriMix) in Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Trimix tear substitutes|DRUG: Hyaluronic acid tear substitute
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Vulvodynia: A Pre-pilot Study
Status: COMPLETED
Conditions: Vulvodynia|Vulvar Vestibulitis|Dyspareunia|Pain
Interventions: OTHER: Active Acupuncture|OTHER: Placebo Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ribociclib in Combination With Everolimus and Dexamethasone in Relapsed ALL
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia ALL
Interventions: DRUG: Ribociclib|DRUG: Dexamethasone|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exogenous Melatonin in Postmenopausal Women With Insomnia
Status: RECRUITING
Conditions: Insomnia
Interventions: DRUG: Melatonin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BPA Levels Relationship With IVF/ICSI Outcomes in Unexplained Infertility
Status: COMPLETED
Conditions: Infertility Unexplained|IVF|Infertility, Female
Interventions: OTHER: BPA levels
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Probiotics on Sputum Inflammation and Pulmonary Infections in Patients With Cystic Fibrosis
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DIETARY_SUPPLEMENT: Bio-25 probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Retention of Nasoenteric Feeding Tubes in Pediatric Patients Using a Nasal Bridle
Status: COMPLETED
Conditions: Feeding Tube Complication
Interventions: DEVICE: AMT BridlePro Device|DEVICE: Adhesive Tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoral Photobiomodulation Therapy to Prevent Oral Mucositis in Patients Undergoing Hematopoietic Cell Transplantation
Status: RECRUITING
Conditions: Myeloablative Allogeneic Hematopoietic Cell Transplantation|Intraoral Photobiomodulation Therapy|Oral Mucositis|Mucosal Ulcer
Interventions: DEVICE: THOR LX2.3 with LED Lollipop
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fecal Microbiota Transplantation for Pancreatitis
Status: COMPLETED
Conditions: Acute Pancreatitis|Intestinal Bacteria Flora Disturbance|Intestinal Dysfunction|Fecal Microbiota Transplantation
Interventions: PROCEDURE: Fecal Microbiota Transplantation|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Visual - Motor Development in Children With Retinopathy of Prematurity
Status: COMPLETED
Conditions: Premature Retinopathy|Visual Impairment|Motor Delay
Interventions: DIAGNOSTIC_TEST: Snellen Test|DIAGNOSTIC_TEST: Autorefractometer|DIAGNOSTIC_TEST: Titmus Stereo Fly Test|DIAGNOSTIC_TEST: Optical Kohlerans Tomography|BEHAVIORAL: Investigation of Visual Motor Integration|BEHAVIORAL: Peabody Developmental Motor Scales - II|BEHAVIORAL: World Health Organization Quality of Life - BREF|BEHAVIORAL: State - Trait Anxiety Inventory
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Lenalidomide in Combination With RICE With Lenalidomide Maintenance Post-Auto Transplant for DLBCL
Status: COMPLETED
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Revlimid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery, Gemcitabine, Cisplatin, and Radiation Therapy in Treating Patients With Stage II or Stage III Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: gemcitabine hydrochloride|GENETIC: gene expression analysis|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: immunohistochemistry staining method|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of an Antimicrobial Stewardship Program in Brazilian ICUs Using Machine Learning Techniques and an Educational Model
Status: UNKNOWN
Conditions: Nosocomial Infection|Sepsis
Interventions: BEHAVIORAL: Implementation of the predictive model for an antimicrobial management program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical and Radiographic Evaluation of Deep Occlusal Carious Molars Treated With Partial Caries Removal With and Without Using Silver Diamine Fluoride (SDF) Prior to Resin Composite Restoration.
Status: UNKNOWN
Conditions: Partial Caries Removal
Interventions: DRUG: Silver diamine fluoride|OTHER: resin modified glassionomer cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Teachers Thriving Together
Status: COMPLETED
Conditions: Social Emotional Competence
Interventions: BEHAVIORAL: ParentCorps FUNdamentals|BEHAVIORAL: ParentCorps 101 E-learning|BEHAVIORAL: Training|BEHAVIORAL: Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bolus vs. Continuous IV Lidocaine Against Post-Extubation Cough in Post-Thyroidectomy Patients
Status: COMPLETED
Conditions: Cough
Interventions: DRUG: Lidocaine IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Addition of Daratumumab to Combination of Bortezomib and Dexamethasone in Participants With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: VELCADE (Bortezomib)|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of HRV Biofeedback on Chronic Kidney Disease Patient.
Status: RECRUITING
Conditions: Autonomic Dysfunction|Inflammatory Response|Chronic Kidney Diseases
Interventions: BEHAVIORAL: heart rate variability biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Study of Anti-Programmed Death-Ligand 1 in Hematologic Malignancy
Status: WITHDRAWN
Conditions: Non-Hodgkin's Lymphoma|Hodgkin Lymphoma|Multiple Myeloma|Chronic Myelogenous Leukemia
Interventions: BIOLOGICAL: BMS-936559 (Anti PD-L1)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gut Microbiota in Liver Cancer (Treated With TKIs In Combination With ICIs)
Status: NOT_YET_RECRUITING
Conditions: Liver Cancer
Interventions: BIOLOGICAL: Oral enterobacterium capsules|DRUG: Lenvatinib + PD-1 monoclonal antibody|BIOLOGICAL: Oral enterobacterium capsules placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Naloxone SR Capsules in Patients With Opioid Induced Constipation
Status: COMPLETED
Conditions: Chronic Pain|Opioid Induced Constipation
Interventions: DRUG: Naloxone SR 5 mg capsules|DRUG: Placebo|DRUG: Naloxone SR 10 mg capsules|DRUG: Naloxone SR 20mg capsules|DRUG: Naloxone SR 2.5 mg capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study for Safety and Efficiency of Therapeutic Angiogenesis for Patients With Limb Ischemia by Transplantation of Human Cord Blood Mononuclear Cell
Status: UNKNOWN
Conditions: Ischemia
Interventions: OTHER: Study for safety and efficiency of therapeutic angiogenesis for patients with limb ischemia by transplantation of human cord blood mononuclear cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Psychoeducational Prevention for the Treatment of Atopic Dermatitis in Youth and Their Families
Status: WITHDRAWN
Conditions: Atopic Dermatitis
Interventions: OTHER: Routine Care/Education|BEHAVIORAL: Psychoeducation/Coping Prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of MAA868 in Patients With Atrial Fibrillation
Status: WITHDRAWN
Conditions: Atrial Fibrillation
Interventions: DRUG: MAA868|DRUG: Apixaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Comparing Pharmacokinetic and Safety of QL2109 and DARZALEX FASPRO® in Healthy Adults
Status: NOT_YET_RECRUITING
Conditions: Tumor
Interventions: DRUG: QL2109|DRUG: DARZALEX FASPRO®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer.
Status: RECRUITING
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Hormone Receptor Positive Breast Carcinoma|Metastatic Breast Carcinoma|Prognostic Stage IV Breast Cancer AJCC v8
Interventions: DRUG: Abemaciclib|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Pediatric Resuscitation
Status: UNKNOWN
Conditions: Cardiac Arrest
Interventions: DEVICE: The CPRmeter|DEVICE: The PocketCPR|DEVICE: Standard BLS|DEVICE: The CPREazy|DEVICE: The CPR PRO APP|DEVICE: The CardioPump|DEVICE: Standard BLS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: AT1001 for the Treatment of Long COVID
Status: RECRUITING
Conditions: Long COVID|Long COVID-19|Post Acute COVID-19 Syndrome|Post Acute Sequelae of COVID-19
Interventions: DRUG: Larazotide Acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mid-transverse Process to Pleura Block in Pediatric Thoracotomy
Status: NOT_YET_RECRUITING
Conditions: Ultrasound Guided Block|Pediatric Surgery|Analgesia
Interventions: DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sodium Oxybate in Patients With Chronic Fatigue Syndrome.
Status: WITHDRAWN
Conditions: Chronic Fatigue Syndrome
Interventions: DRUG: Sodium oxybate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Flow Diverter Stent for Endovascular Treatment of Unruptured Saccular Wide-necked Intracranial Aneurysms
Status: COMPLETED
Conditions: Intracranial Aneurysm
Interventions: DEVICE: PIPELINE flow diverter stent|DEVICE: Coils, with or without expendable stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Erlotinib With or Without Investigational Drug (CS-7017) in Subjects With Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Advanced Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: CS-7017|DRUG: erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of CHOICE-AYA on Contraceptive Use, Continuation and Satisfaction
Status: ENROLLING_BY_INVITATION
Conditions: Contraception Behavior|Sexual Behavior|Reproductive Behavior
Interventions: BEHAVIORAL: CHOICE-AYA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Placing Trust in Endoscopic Ultrasonography: Impact on Planning Conformal Radiotherapy of Cancer of the Esophagus and Rectum
Status: COMPLETED
Conditions: Oesophageal Cancer|Rectal Cancer
Interventions: DEVICE: radio opaque markers (Echo Tip Ultra Fiducial Needle - ETUF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melatonin for Post Operative Delirium Prevention in Elderly Patients
Status: COMPLETED
Conditions: Delirium in Old Age
Interventions: DRUG: Melatonin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pre Bypass Ultrafiltration (PBUF) in Children Requiring Cardiopulmonary Bypass
Status: TERMINATED
Conditions: Congenital Heart Disease
Interventions: OTHER: Use of prebypass ultrafiltration (PBUF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Lateral Flow Urine Lipoarabinomannan (LAM) Test for Diagnosis of Tuberculosis
Status: UNKNOWN
Conditions: Tuberculosis|Tuberculosis, Pulmonary|Tuberculosis, Miliary
Interventions: DEVICE: Alere "Determine" lateral-flow urine lipoarabinomannan assay|DEVICE: Alere "Clearview" ELISA urine LAM assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Compare Vaginal Estrogen and Platelet-rich Plasma Over Women With Genitourinary Syndrome of Menopause
Status: NOT_YET_RECRUITING
Conditions: Menopause|Platelet-rich Plasma|Estrogen Replacement Therapy|Vaginal Atrophy
Interventions: DRUG: Vaginal estrogen supplement|PROCEDURE: Platelet-rich plasma injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparative Study of the Efficacy of Penciclovir 10mg/g (1%) Cream in Preventing the Appearance of Classical Lesion in Recurrent Cold Sore Sufferers
Status: COMPLETED
Conditions: Cold Sore
Interventions: DRUG: Penciclovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Incidence and Severity of Neuropsychiatric Adverse Events of Efavirenz Given as a Stepped Dosage vs. the Usual Dosage
Status: COMPLETED
Conditions: HIV-1 Infection|HIV Infection
Interventions: DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of CASAD in Patients With Diarrhea Related to Medullary Thyroid Cancer
Status: UNKNOWN
Conditions: Diarrhea|Medullary Thyroid Cancer
Interventions: DRUG: CASAD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compartive Study Between Caudal and Perianal Block During Anal Sphincter Sparing Procedures Under General Anesthesia
Status: RECRUITING
Conditions: Acute Post Operative Pain|Motor Activity
Interventions: PROCEDURE: caudal block|PROCEDURE: perianal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety & Immunogenicity Study of 10-Valent Pneumococcal Conjugate Vaccine When Administered as a 2-Dose Schedule
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: GSK Biologicals' 10-valent pneumococcal conjugate vaccine.|BIOLOGICAL: Infanrix hexa.|BIOLOGICAL: Infanrix-IPV/Hib.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Open-label Study of the Absorption, Metabolism, and Excretion of [14C]TVB-2640 Following a Single Oral Dose in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: [14C]-TVB-2640
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lidocaine Injection Versus Sham Needling in Treating Whiplash Associated Disorder
Status: WITHDRAWN
Conditions: Whiplash Injuries|Neck Pain
Interventions: PROCEDURE: Lidocaine|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT