pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison in Japan T80/A5 (Telmisartan 80 mg and Amlodipine 5 mg) and T40/A5 (Telmisartan 40 mg and Amlodipine 5 mg)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: 40 mg telmisartan|DRUG: 5 mg amlodipine|DRUG: 5 mg amlodipine|DRUG: 80 mg telmisartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Focused Versus Enhanced Cognitive Behavioral Therapy for Treating Women With Bulimia Nervosa
Status: COMPLETED
Conditions: Eating Disorders
Interventions: BEHAVIORAL: Cognitive behavioral therapy - focused (CBT-EF)|BEHAVIORAL: Cognitive behavioral therapy - broad (EB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Continuous vs. Intermittent Caloric Restriction on Fat Los
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Continuous Caloric Restriction versus Intermittent Caloric Restriction on Fat Loss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Healthy Toddlers
Status: COMPLETED
Conditions: Meningitis|Meningococcal Meningitis|Meningococcal Infections
Interventions: BIOLOGICAL: Meningococcal Polysaccharide (Serogroups A, C, Y, and W) Tetanus Toxoid Conjugate Vaccine|BIOLOGICAL: Meningococcal Polysaccharide groups A, C, W-135 and Y Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Tolerability of LY3000328 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Placebo|DRUG: LY3000328
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Finding Study of Albuterol Sulfate in Patients With Intermittent or Persistent Mild Asthma
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: albuterol sufate DPI (TBS-7) dose 1|DRUG: albuterol sufate DPI (TBS-7) dose 2|DRUG: albuterol sufate DPI (TBS-7) dose 3|OTHER: Placebo|DRUG: Albuterol|DRUG: Albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of Surgical Treatments for Vulvar and Vaginal Dysplasia
Status: COMPLETED
Conditions: Vulvar Dysplasia|Vaginal Dysplasia
Interventions: PROCEDURE: CO2 laser surgery|PROCEDURE: ultrasonic surgical aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Ursodeoxycholic Acid, Silymarin, Antioxidants and Colchicine on Fibrosis Regression in HCV After SVR
Status: COMPLETED
Conditions: Fibrosis, Liver
Interventions: DRUG: silymarin|DRUG: Ursodeoxycholic Acid|DRUG: Antioxidants|DRUG: Colchicine|OTHER: FOLLOW UP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyaluronate for the Treatment and Prevention of Recurrent Urinary Tract Infection in Women Suffering Atrophic Vaginitis
Status: UNKNOWN
Conditions: Atrophic Vaginitis|Urinary Tract Infections
Interventions: DEVICE: Hyalofemme|DEVICE: Ialuril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Modified Diet, Exercise and Electrical Swallowing Muscle Stimulation on Swallowing Function and Quality of Life in Elderly Patients With Oropharyngeal Dysphagia
Status: COMPLETED
Conditions: Oropharyngeal Dysphagia
Interventions: OTHER: FEES, treatment with modified diet, electrical swallowing muscle stimulation.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Effectiveness and Safety of Risperidone in the Treatment of Behavioral Disturbances in Patients With Dementia
Status: COMPLETED
Conditions: Dementia|Alzheimer Disease|Vascular Dementia
Interventions: DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab, Erlotinib, and Imatinib in the Treatment of Advanced Renal Cell Carcinoma
Status: COMPLETED
Conditions: Clear Cell Renal Cell Carcinoma
Interventions: DRUG: Bevacizumab|DRUG: Erlotinib|DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Budesonide Versus Fluticasone for Treatment of Eosinophilic Esophagitis
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: Oral Viscous Budesonide|DRUG: Fluticasone MDI|DRUG: Placebo slurry|DRUG: Placebo inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Rufinamide and Oxcarbazepine on Nerve Excitability, Hyperalgesia, Allodynia and Flare Reaction Compared to Placebo. A Monocenter, Randomized, Double-blind, Cross-over Study
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Rufinamid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Myocardial Infarction Prediction
Status: COMPLETED
Conditions: Myocardial Infarction|Artificial Neural Network
Interventions: OTHER: ANN prediction of myocardial infarction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Pethidine, Ketorolac And Xylocaine Gel As Analgesics For Pain Control In Shockwave Lithotripsy
Status: COMPLETED
Conditions: Analgesia|Urolithiasis
Interventions: DRUG: Pethidine|DRUG: Ketorolac|DRUG: Xylocaine Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cognitive/Physical Computer-Game Blended Training With Personalized Brain Network Activation Technology for the Elderly
Status: COMPLETED
Conditions: Mild Cognitive Impairment, So Stated|Mild Dementia|Healthy
Interventions: BEHAVIORAL: Alterniity Augmented Reality (AAR)|BEHAVIORAL: VideoGrade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: lithium|DRUG: valproate|DRUG: bupropion|DRUG: paroxetine|DRUG: lamotrigine|DRUG: risperidone|DRUG: inositol|DRUG: tranylcypromine|BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Family-focused Therapy|BEHAVIORAL: Interpersonal and Social Rhythms Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Exercise and Pain Sensitivity
Status: TERMINATED
Conditions: Knee Pain
Interventions: OTHER: Knee muscle strengthening exercises|OTHER: Upper extremity strengthening exercises|OTHER: Cardiovascular fitness exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Endotoxin & Cytokines. Do Protein Loss and Metabolic Effects Depend on Central Nervous System (CNS) Activation of Stress Hormones or on Local Mechanisms in Muscle and Fat?
Status: COMPLETED
Conditions: Inflammation|Glucose Metabolism Disorders
Interventions: BIOLOGICAL: TNF-alpha|BIOLOGICAL: Endotoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose:
Clinical trial: The Protective Effect of Prostaglandin on Coronary Microcirculation and Ventricular Remodeling After Reperfusion Therapy in Acute ST-segment Elevation Myocardial Infarction
Status: UNKNOWN
Conditions: STEMI
Interventions: DRUG: beprostaglandin sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Verify the Efficacy of Z-338 in Subjects With Functional Dyspepsia
Status: COMPLETED
Conditions: Functional Dyspepsia
Interventions: DRUG: Z-338|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RVU120 for Treatment of Anemia in Patients With Lower-risk Myelodysplastic Neoplasms
Status: NOT_YET_RECRUITING
Conditions: Low Risk Myelodysplastic Syndromes
Interventions: DRUG: RVU120 (SEL120)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Gastrointestinal Manifestation of Fabry's Disease
Status: COMPLETED
Conditions: Fabry's Disease
Interventions: DEVICE: Smartpill|PROCEDURE: Endoscopic Mucosal Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ABTL0812 in Combination With FOLFIRINOX for First-line Treatment of Metastatic Pancreatic Study
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: ABTL0812|DRUG: Folfirinox|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: HPA Antibodies and the Distribution of Antigen and Antibodies
Status: COMPLETED
Conditions: Blood Disease|Platelet Refractoriness|Antibody-mediated Rejection
Interventions: PROCEDURE: same type infusion of main HPA antigen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dietary Intervention and Vascular Function
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: SFA diet|DIETARY_SUPPLEMENT: MUFA diet|DIETARY_SUPPLEMENT: n-6 PUFA diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Dietary Fibers and Satiety in Bariatric Patients
Status: COMPLETED
Conditions: Bariatric Surgery Candidate
Interventions: DIETARY_SUPPLEMENT: Fiber or Placebo (depending on the randomization)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Oral Ixazomib Maintenance Therapy in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Not Treated With Stem Cell Transplantation (SCT)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Placebo|DRUG: Ixazomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Linagliptin Versus Placebo in Type 2 Diabetic Patients With Inadequate Glycaemic Control on Metformin in Combination With Pioglitazone
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: Linagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics & Tolerability Study of MAP0004 Co-administered With Ketoconazole
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: MAP0004|DRUG: IV DHE|DRUG: Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of NAC in cT0 Muscle-invasive Bladder Cancer After Maximal TURBt
Status: RECRUITING
Conditions: Muscle-Invasive Bladder Carcinoma|Chemotherapy Effect|Surgery
Interventions: DRUG: cisplatin based neoadjuvant chemotherapy|PROCEDURE: Radical cystectomy alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Silicone Hydrogel Multifocal Contact Lenses
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: Dailies Total 1® Multifocal Contact Lenses|DEVICE: Air Optix® Multifocal Contact Lenses Plus HydraGlyde®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Diabetic Foot Ulcers-Comparing Transforming Powder to Standard of Care
Status: RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: Transforming Powder Dressing|OTHER: Standard of care topical wound agents and dressings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Conversion From Tacrolimus to Sirolimus in African American Renal Transplant Recipients
Status: UNKNOWN
Conditions: Glomerular Filtration Rate|Chronic Allograft Nephropathy
Interventions: DRUG: sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association of Intravenous Ketamine With Thoracic Epidural Analgesia: Effects on Pain and Respiratory Function Following Thoracotomy.
Status: TERMINATED
Conditions: Thoracotomy
Interventions: DRUG: ketamine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of O2 and/or CO2 Inhalation on Rest and Exercise Pulmonary Hemodynamic
Status: COMPLETED
Conditions: Pulmonary Vascular Sensibility in Hypoxia|Hypercapnia|Hypoxia and Hypercapnia
Interventions: DEVICE: Hypercapnia inhalation (Altitrainer NP 190)|DEVICE: Hypoxia and hypercapnia (Altitrainer NP 190)|DEVICE: Hypoxia inhalation (Altitrainer NP 190)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Study of Ammoxetine Hydrochloride Enteric-coated Tablets in Subjects With Depression
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Disorder (MDD)
Interventions: DRUG: Ammoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Study of PF-04991532 in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 2|Glucose Metabolism Disorders
Interventions: DRUG: PF-04991532|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Cryocompression to Reduce Chemotherapy-induced Peripheral Neuropathy in Gynecologic Cancer - COHORT 2
Status: RECRUITING
Conditions: Gynecologic Cancer|Chemotherapy-induced Peripheral Neuropathy
Interventions: BEHAVIORAL: Cryotherapy|BEHAVIORAL: Compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease
Status: RECRUITING
Conditions: Acute Myocardial Infarction|Coronary Artery Disease
Interventions: PROCEDURE: Physiology-guided NCL PCI|PROCEDURE: Angiography-guided NCL PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Dual Antiplatelet Therapy: Platelet Function and Influence of Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Cardiopulmonary Bypass|Platelet Disorder|Bleeding Disorder|Platelet Dysfunction Due to Drugs
Interventions: PROCEDURE: CPB Low Dose|PROCEDURE: CPB High Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study on the Safety and Efficacy of GP681 Tablets in the Treatment of Uncomplicated Acute Influenza
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: GP681 tablet|DRUG: GP681 Simulant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetpmidine Versus Ketamine for Postoperative Sore Throat in Sinus Surgery
Status: COMPLETED
Conditions: Sore Throat
Interventions: DRUG: Dexmedetomidine|DRUG: Ketamine|OTHER: saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Use of a Disk of Amniotic Membrane (Visio-AMTRIX) in Postoperative Care After PKR
Status: TERMINATED
Conditions: Myopia|Astigmatism|Hypermetropia
Interventions: OTHER: Therapeutic lens alone|OTHER: Therapeutic lens + amniotic membrane (Visio-AMTRIX)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Different Hydration Strategies Associated With Aerobic Exercise In Coronary
Status: UNKNOWN
Conditions: Coronary Disease
Interventions: OTHER: Treadmill aerobic exercise without water intake|OTHER: Treadmill aerobic exercise with water intake of a predetermined amount.|OTHER: Treadmill aerobic exercise with water intake according to the desire to drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Digestive Properties of Carbohydrate-based Foods
Status: COMPLETED
Conditions: Obesity|Diabetes Mellitus, Type 2|Appetitive Behavior
Interventions: OTHER: Pearl millet couscous - made in Senegal|OTHER: Pearl millet couscous - made in USA|OTHER: Pearl millet thick porridge|OTHER: Wheat couscous|OTHER: White rice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intraocular Pressure Control After Anterior Segment Laser - Comparison Between 2 Drugs
Status: UNKNOWN
Conditions: Glaucoma, Narrow Angle
Interventions: PROCEDURE: YAG laser peripheral iridotomy|PROCEDURE: YAG laser peripheral iridotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of the Safety and Clinical Efficacy of Topical Dermacyn™ Wound Care to Treat Mild Diabetic Foot Infections
Status: COMPLETED
Conditions: Foot Ulcer, Diabetic
Interventions: DRUG: Topical Dermacyn|DRUG: Topical Dermacyn and Levofloxacin|DRUG: Topical Saline and Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extracts of Amla, Walnut Leaf, Red Yeast Rice and Olive in Cardiovascular Prevention
Status: RECRUITING
Conditions: Low-Density-Lipoprotein-Type [LDL] Hyperlipoproteinemia
Interventions: DIETARY_SUPPLEMENT: Cholesfytol NG|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Flexible Tip Bougie Catheter Intubation
Status: COMPLETED
Conditions: Emergency Medicine|Endotracheal Intubation|Cardiopulmonary Arrest
Interventions: DEVICE: the standard Bougie stylet for difficult intubation|DEVICE: The new Flexible Tip Bougie catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Bioequivalence of Perindopril Tert-butylamine Tablets Taken on an Empty Stomach in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Perindopril tert-Butylamine tablets （ Produced by Haisco）|DRUG: Perindopril tert-Butylamine tablets（ACERTIL®）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect of Bupivacaine Concentration on Ultrasound Guided Pericapsular Group Nerve Block Efficacy in Hip Surgery Patients
Status: COMPLETED
Conditions: Perioperative Pain
Interventions: DRUG: Bupivacain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Factors for Resection and Survival in Type A Borderline Resectable Pancreatic Ductal Adenocarcinoma Patients After Neoadjuvant Therapy
Status: UNKNOWN
Conditions: Carcinoma, Pancreatic Ductal
Interventions: PROCEDURE: Resection|PROCEDURE: No Resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study to Evaluate SYL1001 Safety and Effect in Patients With Ocular Pain
Status: COMPLETED
Conditions: Ocular Pain|Dry Eye Syndrome
Interventions: DRUG: SYL1001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of a CCK Receptor Antagonist Proglumide in Management of Chronic Pancreatitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Safety Issues|Pain|Pancreas Fibrosis
Interventions: DRUG: Proglumide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IV vs IM Oxytocin in the Third Stage of Labor for Prevention of Postpartum Hemorrhage
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Oxytocin|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Grain Exercise Trial - Whole Grain Versus no Grain With or Without Physiotherapy-promoted Exercise for Waist Loss
Status: COMPLETED
Conditions: Abdominal Obesity|Cardiovascular Diseases|Diabetes Type 2|Hypertension|Overweight
Interventions: BEHAVIORAL: Diet A|BEHAVIORAL: Diet B|BEHAVIORAL: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Feasibility and Acceptability of Conducting a Phase III Randomised Controlled Trial Comparing Stereotactic Ablative Radiotherapy With Surgery in paTients With Peripheral Stage I nOn-small Cell Lung Cancer cOnsidered Higher Risk of Complications From Surgical Resection
Status: COMPLETED
Conditions: Oncology
Interventions: PROCEDURE: Treatment by Surgical resection|PROCEDURE: Stereotactic Ablative Radiotherapy (SABR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liverpool Lung Project: Risk Factors and Genetic Markers in Healthy Participants and Patients With Lung Cancer
Status: UNKNOWN
Conditions: Health Status Unknown|Lung Cancer
Interventions: GENETIC: DNA methylation analysis|GENETIC: DNA stability analysis|GENETIC: gene expression analysis|OTHER: epidemiologic study|OTHER: study of socioeconomic and demographic variables|PROCEDURE: biopsy|PROCEDURE: evaluation of cancer risk factors|PROCEDURE: study of high risk factors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy
Status: RECRUITING
Conditions: Muscular Dystrophies|Muscular Dystrophy, Duchenne|Muscular Disorders, Atrophic|Muscular Diseases|Neuromuscular Diseases|Genetic Diseases, X-Linked|Genetic Diseases, Inborn|Nervous System Diseases
Interventions: BIOLOGICAL: CAP-1002|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Treximet Improve Productivity and Patient Satisfaction Due to Sustained Response and Consistency of Response?
Status: COMPLETED
Conditions: Workplace Migraine Treatment
Interventions: DRUG: Triptan|DRUG: Treximet 85Mg-500Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Systematic Work Environment Model Incorporating Web-based Neck-specific Exercise for Dental Staff With Neck Pain
Status: WITHDRAWN
Conditions: Workplace|Neck Pain|Exercise
Interventions: OTHER: SWEA|OTHER: Neck-specific exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Four Week, Open-Label Study of Azithromycin Ophthalmic Solution, 1% (P08641)
Status: TERMINATED
Conditions: Posterior Blepharoconjunctivitis
Interventions: DRUG: Azithromycin ophthalmic solution, 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Adherence and Clinical Outcome in Cystic Fibrosis (CF) Patients
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: BEHAVIORAL: Frequent Scheduled CF clinic visits|BEHAVIORAL: frequent telephone calls to patients pre and post visits to the clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Belantamab Mafodotin, Cyclophosphamide, and Dexamethasone in Relapsed/Refractory Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: DRUG: Belantamab Mafodotin, Cyclophosphamide and Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Antioxidants Supplementation in Chronic Pancreatitis
Status: COMPLETED
Conditions: Chronic Pancreatitis
Interventions: DIETARY_SUPPLEMENT: Antioxidants|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predicting Relapse of Ulcerative Colitis With Gastrointestinal Ultrasound
Status: UNKNOWN
Conditions: Ulcerative Colitis in Remission|Ultrasound|Relapse/Recurrence
Interventions: DIAGNOSTIC_TEST: Ultrasound|DIAGNOSTIC_TEST: Analysis of prouroguanyline and uroguanyline in full blood
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Explore the Safety and Tolerability of Acthar in Patients With Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Repository corticotropin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chloroprocaine 1% Versus Ropivacaine 0,75% During Cesarean Section
Status: RECRUITING
Conditions: Cesarean Section|Local Anesthetic
Interventions: DRUG: Chloroprocaine 1% Injectable Solution|DRUG: Ropivacaine 0.75% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atypical Orofacial Pain Diagnostics and Differentiation.
Status: UNKNOWN
Conditions: Persistent Idiopathic Facial Pain
Interventions: BEHAVIORAL: Self-evaluating questionnaires|BEHAVIORAL: iMotions analysis platform
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study In Women And Men With Metastatic Breast Cancer That Have Overexpression Of ErbB2
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: Lapatinib (GW572016) oral tablets|DRUG: Paclitaxel infusion|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Restarting Anticoagulation After Traumatic Intracranial Hemorrhage
Status: NOT_YET_RECRUITING
Conditions: Hemorrhage|Intracranial Hemorrhages|Bleeding|Trauma
Interventions: DRUG: Anticoagulants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Oxytocin Trial in Prader-Willi Syndrome
Status: COMPLETED
Conditions: Prader Willi Syndrome
Interventions: DRUG: Intranasal oxytocin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of ABT-126 in Stable Subjects With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: ABT-126|DRUG: Placebo for ABT-126
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of G207, a Tumor-Killing Virus, in Patients With Recurrent Brain Cancer
Status: COMPLETED
Conditions: Glioma|Astrocytoma|Glioblastoma
Interventions: DRUG: G207, an oncolytic virus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin and Etoposide Plus Radiation Followed By Nivolumab/Placebo For Locally Advanced NSCLC
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: RADIATION: Radiation Therapy (RT)|DRUG: Cisplatin|DRUG: Etoposide|DRUG: Nivolumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: viTAmin K2 and rEcOVery From ExeRcise
Status: COMPLETED
Conditions: Inflammation|Oxidative Stress|Vitamin K|Exercise|Strength|Recovery
Interventions: DIETARY_SUPPLEMENT: Vitamin K2|DIETARY_SUPPLEMENT: Micro-crystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Late Phase Administration Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation
Status: WITHDRAWN
Conditions: Asthma
Interventions: BIOLOGICAL: Anakinra|OTHER: Anakinra Matching Placebo|DRUG: Dermatophagoides Farinae
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact Assessment of Simulation-Based Education on Anesthesiology Trainee in Ultrasound-Guided Transversus Abdominis Plane Block Using an Anesthetized Porcine Model
Status: COMPLETED
Conditions: Anesthesiology Trainee
Interventions: OTHER: Simulation-Based Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Paracetamol Study in Patients With Low Muscle Mass
Status: RECRUITING
Conditions: SMA II|Cerebral Palsy
Interventions: DRUG: Paracetamol 120Mg/5mL Oral Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Study on the Feasibility and Effectiveness of Per-Oral Endoscopic Myotomy (P.O.E.M.) for Treatment of Primary Esophageal Motility Disorders
Status: UNKNOWN
Conditions: Primary Esophageal Motility Disorders Including Achalasia and Hypertensive LES
Interventions: PROCEDURE: Per-Oral Endoscopic Myotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Efficacy of Red Dichromatic Imaging (RDI) in Achieving Hemostasis During POEM Using GF 1500 UGI Scope
Status: RECRUITING
Conditions: POEMS Syndrome|Hemostatic Disorder
Interventions: RADIATION: White Light Imaging|RADIATION: Red Light Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Pranayama Breathing Technique in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Nebulizer|OTHER: Breathing Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic, Tolerability and Safety Study of Icatibant in Children and Adolescents With Hereditary Angioedema
Status: COMPLETED
Conditions: Hereditary Angioedema (HAE)
Interventions: DRUG: icatibant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of an Intervention to Improve Use of Life-saving Medications for Heart Disease
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: BEHAVIORAL: oral education & written tips for remembering medications|DEVICE: pill box|DEVICE: pocket medication card|BEHAVIORAL: sharing information with community pharmacist|BEHAVIORAL: Medication use evaluations by community pharmacist|BEHAVIORAL: informing physician if patient has stopped a medication|BEHAVIORAL: Routine discharge counseling|OTHER: Letter to physician/discharge summary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Caudal Ropivacaine With or Without Dexmedetomidine for Post Operative Analgesia
Status: COMPLETED
Conditions: Ropivacaine|Infraumbilical Surgery|Dexmedetomidine|Analgesia
Interventions: DRUG: ropivacaine with dexmedetomidine|DRUG: Ropivacaine with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness and Safety of a Flexible Family Visitation Model for Delirium Prevention in Adult Intensive Care Units: a Cluster-randomized, Crossover Trial (The ICU Visits Study)
Status: COMPLETED
Conditions: Delirium
Interventions: OTHER: Flexible Family Visitation Model (FFVM)|OTHER: Restrictive Family Visitation Model (RFVM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Characterization of Tissue-Specific Immune Responses to Bronchoscopic Instillation of Mycobacterial Antigens Into the Human Lung
Status: RECRUITING
Conditions: Healthy|Latent Tuberculosis Infection (LTBI)
Interventions: DRUG: Tuberculin Purified Protein Derivative
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Triamcinolone or Bevacizumab for Central Retinal Vein Occlusion With Poor Vision
Status: COMPLETED
Conditions: Central Retinal Vein Occlusion With 20/200 or Worse Visual Acuity
Interventions: PROCEDURE: intravitreal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Treatments Used for White Spot Lesions After Orthodontic Treatment.
Status: COMPLETED
Conditions: Tooth Demineralization
Interventions: PROCEDURE: MI Paste Plus|PROCEDURE: PreviDent Fluoride Varnish|PROCEDURE: Normal Home Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Western Kenya Integrated COVID-19 Response
Status: UNKNOWN
Conditions: Covid19
Interventions: OTHER: Training of youth, community health assistants and community health workers.|OTHER: Training clinicians in basic critical care and the management of severe COVID-19 cases
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of Efficacy & Safety for a New Wound Dressing Urgo 310 3166 in the Local Treatment of VLU or Mixed Leg Ulcers
Status: UNKNOWN
Conditions: Leg Ulcers
Interventions: DEVICE: Urgo 3103166|DEVICE: Aquacel Extra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Impact of Cobas® Eplex Blood Culture Panels for the Diagnosis of Bacteremia and Fungemia
Status: NOT_YET_RECRUITING
Conditions: Bloodstream Infection
Interventions: DIAGNOSTIC_TEST: cobas eplex multiplex PCR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prediction of Neoadjuvant Chemotherapy Response Using Contrast-Enhanced Ultrasound in Patients With Locally Advanced Breast Cancer
Status: RECRUITING
Conditions: Anatomic Stage III Breast Cancer AJCC v8|Locally Advanced Breast Carcinoma
Interventions: PROCEDURE: Contrast-Enhanced Ultrasound|DRUG: Perflutren Lipid Microspheres|PROCEDURE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Penpulimab Plus R2-GemOx Regimen in Relapsed or Refractory DLBCL
Status: NOT_YET_RECRUITING
Conditions: Lymphoma, Large B-Cell, Diffuse|Neoplasms by Histologic Type
Interventions: DRUG: penpulimab, lenalidomide, Rituximab, Gemcitabine, Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lopinavir/Ritonavir for the Treatment of COVID-19 Positive Patients With Cancer and Immune Suppression in the Last Year
Status: WITHDRAWN
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm|Symptomatic COVID-19 Infection Laboratory-Confirmed
Interventions: DRUG: Lopinavir/Ritonavir|DRUG: Placebo Administration|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antidiuretic Function Before and During Treatment With SGLT2 Inhibitors
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Arterial Hypertension|Body Weight Changes
Interventions: DRUG: SGLT2 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Adaptation of Dialectical Behavior Therapy Skills-Groups for Individuals With Suicidal Ideation and Depression
Status: COMPLETED
Conditions: Suicidal Ideation|Major Depressive Disorder
Interventions: BEHAVIORAL: Dialectical Behavior Therapy Skills (DBT-S) Groups|BEHAVIORAL: Wait List-Treatment as Usual|BEHAVIORAL: No intervention-treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Randomized Trial of Topical Vaginal Fluorouracil (5-Fluorouracil, 5-FU) Maintenance Therapy Versus Observation After Standard Treatment for High-Grade Cervical Dysplasia in HIV-Infected Women
Status: COMPLETED
Conditions: HIV Infections|Cervix, Dysplasia
Interventions: DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: Topical Cannabidiol for the Treatment of Chemotherapy-Induced Peripheral Neuropathy
Status: COMPLETED
Conditions: Chemotherapy-Induced Peripheral Neuropathy|Malignant Solid Neoplasm
Interventions: DRUG: Cannabidiol|DRUG: Placebo Administration|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Lansoprazole in Combination With Ecabet Sodium for Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: ecabet sodium|DRUG: lansoprazole|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MINGO Supplemental Trial in X-linked Dystonia-Parkinsonism Patients
Status: COMPLETED
Conditions: X-Linked Dystonia Parkinsonism
Interventions: DIETARY_SUPPLEMENT: MINGO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reduction of Cord Blood Transplantation Toxicity in Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: OTHER: Cord blood transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Paricalcitol in Kidney Transplant Recipients
Status: COMPLETED
Conditions: Transplant; Failure, Kidney|Renal Disease, End Stage|Hyperparathyroidism, Secondary
Interventions: DRUG: Paricalcitol|OTHER: Corticosteroid Avoidance Immune Suppression Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Immunogenicity of V419 in Healthy Infants When Given at 2, 4, and 11 to 12 Months (V419-008)
Status: COMPLETED
Conditions: Bacterial Infections|Virus Diseases
Interventions: BIOLOGICAL: PR5I|BIOLOGICAL: Rotavirus vaccine|BIOLOGICAL: Prevenar 13™|BIOLOGICAL: INFANRIX™ hexa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical And Radiographic Evaluation Of Premixed Bio-ceramic MTA In Indirect Pulp Capping Of Young Permanent Molars
Status: NOT_YET_RECRUITING
Conditions: Indirect Pulp Capping
Interventions: DRUG: Premixed Bio-ceramic MTA|DRUG: Calcium hydroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture as an Adjunctive Therapy for Covid-19 Omicron Randomised Controlled Trial in Patients With Moderate/Severe Pneumonia
Status: RECRUITING
Conditions: Acupuncture|Covid-19 Omicron|Pulmonary Function
Interventions: OTHER: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DWI in the Diagnosis of Histological Types of Nephroblastoma in Children
Status: UNKNOWN
Conditions: Nephroblastoma (Wilms Tumour)
Interventions: DIAGNOSTIC_TEST: MRI DWI sequence (ADC values)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRCHIVMAB0115-00-AB (VRC01.23LS), Administered Intravenously or Subcutaneously to Healthy Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV
Interventions: BIOLOGICAL: VRC-HIVMAB0115-00-AB
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigation of the Effectiveness of a Structured Squat-based Program in Knee Osteoarthritis Rehabilitation
Status: COMPLETED
Conditions: Osteoarthritis Knees Both|Pain, Chronic|Walking, Difficulty
Interventions: DEVICE: Flywheel exercise|OTHER: Home exercise|DEVICE: Electrotherapy group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Stem Cells in Newborns With Oxygen Deprivation
Status: UNKNOWN
Conditions: Apgar; 0-3 at 1 Minute|Metabolic Acidosis|Hypoxia, Brain|Multiple Organ Failure
Interventions: PROCEDURE: Application of Stem Cells|PROCEDURE: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Two Doses of WRAIR Dengue Vaccine Administered Six Months Apart to Healthy Adults and Children
Status: COMPLETED
Conditions: Dengue Fever|Dengue Hemorrhagic Fever|Dengue Shock Syndrome
Interventions: OTHER: Placebo|BIOLOGICAL: T-DEN-Post-Transfection F17|BIOLOGICAL: T-DEN-Post-Transfection F19
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of High Dose vs. Standard Dose Influenza Vaccine in Inflammatory Bowel Disease Patients
Status: COMPLETED
Conditions: Inflammatory Bowel Disease (IBD)
Interventions: BIOLOGICAL: Standard dose Influenza vaccine (SDIV)|BIOLOGICAL: High dose influenza vaccine (HDIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acute Myocardial Infarction With HyperOxemic Therapy II (AMIHOT II)
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DEVICE: AO Therapy (aqueous oxygen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: R-RPLND as First-line Treatment for Clinical Stage IIA/B Testicular Seminoma
Status: RECRUITING
Conditions: Lymphadenopathy Retroperitoneal|Stage II Testicular Seminoma
Interventions: PROCEDURE: Robotic Retroperitoneal Lymph Node Dissection (RPLND)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Appetite in Crohn's Disease: The Role of the Brain in the Control of Food Intake
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: OTHER: Dodecanoate acid and saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE