pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Neoadjuvant Hiltonol® (PolyICLC) for Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Intratumoral (IT) Poly ICLC 0.5 mg|BIOLOGICAL: Intratumoral (IT) Poly ICLC 1.0 mg|BIOLOGICAL: Intramuscular (IM) Poly ICLC|PROCEDURE: Radical Prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Double-layer Versus Single-layer Uterine Closure Suture in Cesarean Section on the Development of Postoperative Uterine Scar Deficiency
Status: UNKNOWN
Conditions: Cesarean Section|Uterine Scar Deficiency|Myometrial Thickness|Single-layer Continuous Uterotomy Suture|Double-layer Continuous Uterotomy Suture|Transvaginal Ultrasound
Interventions: PROCEDURE: uterine closure during cesarean section
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Evaluating the Efficacy and Safety of EndoTAG®-1 in Combination With Paclitaxel and Gemcitabine Compared With Paclitaxel and Gemcitabine as First-line Therapy in Patients With Visceral Metastatic Triple-negative Breast Cancer
Status: SUSPENDED
Conditions: Triple-Negative Breast Cancer
Interventions: DRUG: EndoTAG-1|DRUG: Paclitaxel|DRUG: Gemcitabine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AMPLIFYing NEOepitope-specific VACcine Responses in Progressive Diffuse Glioma
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Glioma
Interventions: DRUG: IDH1R132H peptide vaccine|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Biological Activity of Cediranib (AZD2171) in Gastro-Intestinal Stromal Tumours(GIST).
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors|Soft Tissue Sarcomas
Interventions: DRUG: AZD2171
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Short- and Long Term Outcomes of Early Routine PCI With the Standard Treatment in Low-intermediate Risk ST-elevation Myocardial Infarction Patients Who Successfully Fibrinolysis.
Status: COMPLETED
Conditions: ST-elevation Myocardial Infarction
Interventions: OTHER: Percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Immunity at the Genital Mucosa of HIV-1 Infected and Healthy Women
Status: TERMINATED
Conditions: HIV Infected Women|Healthy Women Volunteers
Interventions: PROCEDURE: vaginal swabs by washing and cytobrush
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Letrozole In Combination With Lapatinib In Neoadjuvant Treatment Of Early Breast Cancer
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: lapatinib|DRUG: letrozole|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction Study of GSK1278863 With Pioglitazone, Rosuvastatin and Trimethoprim in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Anaemia
Interventions: DRUG: GSK1278863 25 mg Tablet|DRUG: Pioglitazone 15 mg Tablet|DRUG: Rosuvastatin 10 mg Tablet|DRUG: Trimethoprim 100 mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AcrySof IQ Toric A-Code Post-Market Clinical Study
Status: COMPLETED
Conditions: Cataract|Astigmatism
Interventions: DEVICE: AcrySof IQ Toric A-code IOL|PROCEDURE: Cataract surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of ULSC in Patients With Polymyositis (PM) and Dermatomyositis (DM)
Status: COMPLETED
Conditions: Polymyositis|Dermatomyositis
Interventions: DRUG: Umbilical Cord Lining Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Labor in Patients With Previous Cesarian Section
Status: UNKNOWN
Conditions: Pregnancy|Previous Cesarian Section|Premature Rupture of Membranes (PROM)
Interventions: DEVICE: Double balloon cervical catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome Following Vitamin C Administration in Sepsis
Status: UNKNOWN
Conditions: Severe Sepsis
Interventions: DRUG: Vitamin C|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan Plus Anlotinib or Further in Combination With Penpulimab for Second-line Treatment of mCRC
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Anlotinib|DRUG: Penpulimab|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Netarsudil for the Prevention of Proliferative Vitreoretinopathy in Patients With Retinal Detachment
Status: NOT_YET_RECRUITING
Conditions: Rhegmatogenous Retinal Detachment|Proliferative Vitreoretinopathy
Interventions: DRUG: Netarsudil Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pre-sleep Protein Supplementation and Load Carriage Recovery in British Army Recruits
Status: COMPLETED
Conditions: Protein-energy; Imbalance|Muscle Soreness
Interventions: DIETARY_SUPPLEMENT: High protein intake|DIETARY_SUPPLEMENT: Moderate protein intake|DIETARY_SUPPLEMENT: Carbohydrate maltodextrin placebo|OTHER: Control no supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Rasagiline in Subjects With Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: DRUG: Rasagiline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Composition for Treating Cirrhosis and Liver Cancer (SB-1121)
Status: COMPLETED
Conditions: Cirrhosis of the Liver
Interventions: DRUG: SB-1121(1)|DRUG: SB-1121(2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Supraglottic Airways for Entrapped Trauma Patients
Status: RECRUITING
Conditions: Airway Obstruction
Interventions: DEVICE: LMA Supreme|DEVICE: SLIPA|DEVICE: I-gel|DEVICE: AuraGain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Compare the Safety and Efficacy of Perrigo's Product to an FDA Approved Product for the Treatment of Secondarily Infected Traumatic Skin Lesions
Status: COMPLETED
Conditions: Secondarily Infected Traumatic Skin Lesions
Interventions: DRUG: Mupirocin Calcium|DRUG: Mupirocin Calcium|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lymph Node Mapping Using Indocyanine Green Solution in Diagnosing Patients With Malignant Melanoma
Status: COMPLETED
Conditions: Recurrent Melanoma
Interventions: DRUG: Indocyanine green solution|DRUG: Isosulfan blue (ISB)|DIAGNOSTIC_TEST: Lymphoscintigraphy with 99-technetium (99Tc) sulfur colloid (TSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Non-invasive Treatment of Root Caries in Older Adults
Status: COMPLETED
Conditions: Root Caries
Interventions: DRUG: Self-administered fluoridated dentifrices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gabapentin Regimens and Their Effects on Opioid Consumption
Status: COMPLETED
Conditions: Knee Osteoarthritis|Knee Pain Chronic|Opioid Use|Opioid Dependence
Interventions: DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: N-Acetyl-Cysteine for Treatment of AGA in Men
Status: UNKNOWN
Conditions: Androgenetic Alopecia
Interventions: DRUG: Minoxidil 5% topically and oral NAC 600 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lapatinib +/- Trastuzumab In Addition To Standard Neoadjuvant Breast Cancer Therapy.
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: Trastuzumab|DRUG: Paclitaxel|DRUG: FEC75|DRUG: Lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: β-blockers Withdrawal in Patients With HFpEF and Chronotropic Incompetence: Effect on Functional Capacity (Preserve-HR)
Status: COMPLETED
Conditions: Heart Failure With Normal Ejection Fraction|Chronotropic Incompetence
Interventions: DRUG: Controlled withdrawal of beta-blockers|DIAGNOSTIC_TEST: Cardiopulmonary Exercise Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Navelbine and Cisplatin Followed by Metronomic Oral Navelbine in Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Neoplasm Malignant
Interventions: DRUG: Vinorelbine Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy to Improve Work and Wellness in Veterans With Mental Illness
Status: ACTIVE_NOT_RECRUITING
Conditions: Posttraumatic Stress Disorders
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy For Work Success (CBTw)|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of T-PRED(TM) Compared to Pred Forte(R)
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: T-PRED|DRUG: Pred Forte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fractional Flow Reserve (FFR) Stability in Non-Culprit Vessels at ST Elevation Myocardial Infarction(STEMI)
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: PROCEDURE: FFR (Fractional Flow Reserve)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Carboplatin With or Without Atezolizumab in Treating Patients With Stage IV Triple Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Triple Negative Breast Cancer|Stage IV Breast Cancer|HER2 Negative|Invasive Breast Cancer
Interventions: DRUG: Atezolizumab|DRUG: Carboplatin|OTHER: Laboratory Biomarker|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Description of Real World Antiviral Effectiveness and Sustainability of the 2-Drug Regimen Dolutegravir + Lamivudine in Untreated and Pre-treated Patients in Routine Clinical Care in Germany
Status: COMPLETED
Conditions: HIV Infections
Interventions: OTHER: HIV Symptom Distress Module Questionnaire|OTHER: HIV treatment satisfaction questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Application of Enhanced Recovery After Surgery (ERAS) for Cardiovascular Surgery in the Correction of Complex Congenital Heart Disease
Status: NOT_YET_RECRUITING
Conditions: Complex Congenital Heart Disease|Enhanced Recovery After Surgery
Interventions: PROCEDURE: ERAS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Neoadjuvant DMPA on Glandular Cellularity in Women Awaiting Hysterectomy
Status: UNKNOWN
Conditions: Grade 1 Endometrial Endometrioid Adenocarcinoma|Grade 2 Endometrial Endometrioid Adenocarcinoma|Complex Atypical Endometrial Hyperplasia
Interventions: DRUG: Depot medroxyprogesterone acetate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label, Randomized Study Evaluating the Absorption and Systemic Pharmacokinetics of Topically Applied IDP-126 Gel in Comparison With Control Gel
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: IDP-126 Gel|DRUG: Control Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Breast Milk Contents in Tandem Breastfeeding and Non-Tandem Breastfeeding Mother
Status: UNKNOWN
Conditions: Tandem Breastfeeding
Interventions: OTHER: tandem breastfeedıng
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of AC0058TA in Patients With Systemic Lupus Erythematosus (SLE)
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: AC0058TA|DRUG: Placebo AC0058TA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability and Pharmacokinetic Study of TAS-114 in Combination With Capecitabine in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: TAS-114/capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture in Reducing Muscle and Bone Symptoms in Women Receiving Letrozole, Exemestane, or Anastrozole for Stage 0, Stage I, Stage II, or Stage III Breast Cancer
Status: COMPLETED
Conditions: Anxiety Disorder|Breast Cancer|Depression|Fatigue|Hot Flashes|Pain|Sleep Disorders
Interventions: PROCEDURE: acupuncture therapy|PROCEDURE: sham intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does Supplementing of Quadriceps Strength With Exoskeleton After Total Knee Arthroplasty in High Risk Population Reduce Transfer to Extended Care Facility (ECF)
Status: WITHDRAWN
Conditions: Primary Knee Replacement Surgery
Interventions: DEVICE: Robotic exoskeleton device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of 123I-Iodometomidate for Adrenal Scintigraphy
Status: COMPLETED
Conditions: Adrenal Tumor|Adrenocortical Carcinoma
Interventions: DRUG: 123I-Iodometomidate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of CAR-T Cells Therapy for Patients With Relapsed and/or Refractory Central Nervous System Hematological Malignancies
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Non-Hodgkin's Lymphoma
Interventions: DRUG: CAR-T cells|PROCEDURE: Ommaya Reservoir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Pharmacodynamics, Safety, Tolerability and Pharmacokinetics of MT-3995 in Type II Diabetic Nephropathy Subjects With Albuminuria
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: MT-3995 Low|DRUG: MT-3995 High|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Digital Learning on Competence in Motivational Interviewing
Status: NOT_YET_RECRUITING
Conditions: Nurse's Role|Motivation
Interventions: BEHAVIORAL: digital learning in motivational interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PTI-125 for Mild-to-moderate Alzheimer's Disease Patients
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Placebo oral tablet|DRUG: Simufilam 100 mg tablet|DRUG: Simufilam 50 mg oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency and Safety a Fixed Combination of Orphenadrine and Diclofenac for Postoperative Analgesia
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: Analgesics Non Opioid (Neodolpasse manufactured by Fresenius Kabi)|DRUG: Analgesics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Efficacy of Risedronate in Preventing Bone Loss in Postmenopausal Women Treated for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Menopause|Osteopenia
Interventions: DRUG: Risedronate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Baby Steps III: Testing a Clinician and Patient Intervention to Promote Smoking Cessation Among Pregnant Women
Status: RECRUITING
Conditions: Smoking Cessation|Pregnancy|Communication Research
Interventions: BEHAVIORAL: Clinician Communication Intervention|OTHER: 5A's lecture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Monitoring Mitophagy In Myeloid Cells Upon Intensive Care
Status: RECRUITING
Conditions: Septicemia
Interventions: BIOLOGICAL: Blood sampling at inclusion|BIOLOGICAL: Blood sampling at 24 hours|OTHER: Data collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparative Efficacy of an Intensified Re-vaccination Scheme for Hepatitis B Virus Infection Among Patients Infected With HIV .
Status: COMPLETED
Conditions: Hepatitis B|HIV
Interventions: BIOLOGICAL: Recombinant Hepatitis B Virus Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Head and Neck Cooling and Heating on Fatigue in Multiple Sclerosis and Healthy Men
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: Cooling of the head and neck|OTHER: Heating of the head and neck
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mindfulness Training Versus Low (FODMAP) Fermentable Oligosaccharides, Disaccharides, Monosaccharides and Polyols Diet
Status: NOT_YET_RECRUITING
Conditions: Irritable Bowel Syndrome (IBS)
Interventions: BEHAVIORAL: Mindfulness-based Attention Training in IBS|OTHER: Low FODMAP Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Esmolol for the Treatment of Hypertension After Intracerebral Hemorrhage Study (ETHICHS)
Status: TERMINATED
Conditions: Hemorrhagic Stroke
Interventions: DRUG: Brevibloc, 10 Mg/mL Intravenous Solution|DRUG: Nitroprusside, Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Home Based tDCS in Fibromyalgia
Status: UNKNOWN
Conditions: Fibromyalgia|Transcranial Direct Current Stimulation
Interventions: DEVICE: Transcranial Direct Current Stimulation - tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Post Anesthetic Recovery Time in Sedated Patients for Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy|Anesthesia
Interventions: DRUG: Midazolam|DRUG: Fentanyl|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficiency of Erector Spinae Plane Block For Patients Undergoing Percutaneous Nephrolithotomy
Status: COMPLETED
Conditions: Nephrolithotomy, Percutaneous|Anesthetics, Local|Nerve Block|Erector Spinae Plane Block|Pain, Postoperative|Anesthesia and Analgesia
Interventions: PROCEDURE: Ultrasound Guided Erector Spinae Plane Block Catheterisation|DRUG: Bupivacaine 0.25% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Sleep Improving Effects of Orange Phenolics
Status: COMPLETED
Conditions: Polyphenols|Sleep|Fatigue
Interventions: DIETARY_SUPPLEMENT: Lozenge containing citrus flavonoid|DIETARY_SUPPLEMENT: Lozenge containing citrus flavonoid formulation|DIETARY_SUPPLEMENT: Identical looking placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: RCT on Bioactive Glass S53P4 in Diabetic Foot Osteomyelitis in the Forefoot (DFORCT)
Status: RECRUITING
Conditions: Osteomyelitis - Foot
Interventions: DEVICE: Bioactive Glass|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation and Metabolism in Vitamin D Deficient Elderly
Status: TERMINATED
Conditions: Vitamin D Deficiency|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: RDA Vitamin D3 only|DIETARY_SUPPLEMENT: Vitamin D2/3 Repletion only|OTHER: Vitamin D2/3 Repletion + AEX|OTHER: Vitamin D2/3 Repletion + RT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Green Tea Extract for Obesity of Psychiatric Patients
Status: COMPLETED
Conditions: Obesity|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Green tea extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ELB139 Given Orally to Patients With Concurrent Panic Disorder, Challenged by CO2 Inhalation After a Single Dose and One Week of Treatment
Status: TERMINATED
Conditions: Panic Disorder
Interventions: DRUG: ELB139
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: LázBarát™ (FeverFriend™) Projekt: Attitude Toward Fever and Its Change in the Healthcare System
Status: ENROLLING_BY_INVITATION
Conditions: Fever|Anxiety|Help-Seeking Behavior|Virus Diseases|Bacterial Infections|Overdose of Analgesic Drug
Interventions: DEVICE: FeverFriend mobile application
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low-dose Quadruple Combination Therapy in Patients With Hypertension
Status: COMPLETED
Conditions: Hypertension|Arterial Hypertension
Interventions: DRUG: Quadruple combination of half doses therapy→Dual combination of standard dose therapy|DRUG: Dual combination of standard dose therapy→ Quadruple combination of half doses therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medication Adherence Intervention in Chronic Recurrent Multifocal Osteomyelitis (CRMO)
Status: TERMINATED
Conditions: Chronic Recurrent Multifocal Osteomyelitis
Interventions: OTHER: Education of medication management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: [E]PANOVA Combined With a [S]TATIN in [P]ATIENTS With HYPERT[R]IGLYCER[I]DEMIA to Reduce Non-HDL CHOLES[T]EROL
Status: COMPLETED
Conditions: Hypertriglyceridemia|Cardiovascular Disease
Interventions: DRUG: Olive oil, 4g|DRUG: omega-3-carboxylic acids, 2g|DRUG: omega-3-carboxylic acids, 4g
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BI 44370 TA in Acute Migraine Attack
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: BI 44370 TA Low Dose|DRUG: Eletriptan|DRUG: Placebo|DRUG: BI 44370 TA Medium Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Single-dose Pharmacokinetics and Safety of Oral Lofexidine in Renally-Impaired Subjects
Status: COMPLETED
Conditions: Renally Impaired Subjects
Interventions: DRUG: lofexidine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Community Health Workers and Teleaudiology as a Culturally-relevant Approach to Improving Access to Hearing Health Care
Status: COMPLETED
Conditions: Hearing Loss
Interventions: BEHAVIORAL: Community Health Workers and Teleaudiology as a Culturally-Relevant Approach to Improving Access to Hearing Health Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combination Therapy to Improve SCI Recovery.
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: OTHER: Daily acute intermittent hypoxia|OTHER: Room air (SHAM)|OTHER: Walking + tSTIM|OTHER: Walking + Sham transcutaneous spinal stimulation (tSHAM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: iCLAS™ for Persistent Atrial Fibrillation
Status: ACTIVE_NOT_RECRUITING
Conditions: Persistent Atrial Fibrillation
Interventions: DEVICE: Adagio AF Cryoablation System (iCLAS™)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Stain Control of Two Stannous Fluoride Dentifrices
Status: COMPLETED
Conditions: Extrinsic Dental Stain|Oral Hygiene
Interventions: OTHER: Stannous fluoride (SnF2, 0.454%), Sodium tripolyphosphate (STP, 5%), 2.0% abrasive silica|OTHER: Stannous fluoride (SnF2, 0.454%), Sodium tripolyphosphate (STP, 5%), abrasive silica (3.5%)|OTHER: Sodium Monofluorophosphate (1000 ppm fluoride ), RDA~80|OTHER: Stannous fluoride (SnF2, 0.454%), RDA~120
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficiency of Manual Therapy on Central Sensitization in Patients With Nonspecific Chronic Back Pain
Status: NOT_YET_RECRUITING
Conditions: Central Sensitization|Manual Therapy
Interventions: OTHER: manual therapy|OTHER: conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CBCT-Guided Navigational Bronchoscopy For Lung Nodules
Status: COMPLETED
Conditions: Peripheral Pulmonary Nodules|Lung; Node|Cone Beam Computed Tomography|Guided Navigation Bronchoscopy
Interventions: RADIATION: Navigation Bronchoscopy|RADIATION: Cone beam computed tomography (CBCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy Study of Empagliflozin and Metformin for 24 Weeks in Treatment Naive Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Hyperglycemia
Interventions: DRUG: Metformin 500 mg bid|DRUG: Metformin 1000 mg bid|DRUG: Empagliflozin low dose qd|DRUG: Empagliflozin high dose qd|DRUG: Empagliflozin low dose bid|DRUG: Metformin 500 mg bid|DRUG: Empagliflozin high dose bid|DRUG: Empagliflozin low dose bid|DRUG: Metformin 1000 mg bid|DRUG: Metformin 500 mg bid|DRUG: Metformin 1000 mg bid|DRUG: Empagliflozin high dose bid|DRUG: Metformin 1000 mg bid|DRUG: Empagliflozin high dose bid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of PV in Combination With Bendamustine and Rituximab for Patients With R/R MCL
Status: NOT_YET_RECRUITING
Conditions: Lymphoma, Mantle-Cell
Interventions: DRUG: Polatuzumab vedotin|DRUG: Bendamustine Hydrochloride|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Susceptibility of Human Volunteers With Different Histo-Blood With Different Histo-Blood Group Antigens to Norovirus
Status: COMPLETED
Conditions: Healthy Adults
Interventions: BIOLOGICAL: Norovirus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Effect of Carnitine Supplementation on Cardiac Function and Lipid Profile in Patients With Drug Resistant Epilepsy on Ketogenic Diet
Status: ACTIVE_NOT_RECRUITING
Conditions: l Carnitine With Ketogenic Diet
Interventions: DRUG: L Carnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Effects of Mitral Valve Repair With the Geoform Ring on Cardiomyopathy
Status: WITHDRAWN
Conditions: Mitral Valve Regurgitation|Congestive Heart Failure|Cardiomyopathy
Interventions: PROCEDURE: 3 dimensional echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liver Positron Emission Tomography (PET) Study of Non Alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Fatty Liver
Interventions: DRUG: Radio pharmaceuticals C-11 Acetate, and C-11 Palmitate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Renal Denervation in Chronic Kidney Disease - RDN-CKD Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Uncontrolled Hypertension|Renal Denervation|Chronic Kidney Disease stage3
Interventions: DEVICE: Renal denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ketamine on Mechanises Underlying Suicidal Ideation and Drug-resistant Major Depression
Status: UNKNOWN
Conditions: Suicidal Ideation|Major Depressive Disorder|Healthy Participants
Interventions: DRUG: Ketamine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adductor Canal Versus Femoral Nerve Block for Analgesia Post Total Knee Arthroscopy
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Chlorhexidine Gluconate Chip (PerioChip®) in Therapy of Peri-implantitis
Status: COMPLETED
Conditions: Peri-Implantitis
Interventions: DRUG: 2.5 mg Chlorhexidine gluconate chip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Scot Sweet Study (Interaction of a Non-nutritive Sweetener With a High-fibre Weight Loss Diet)
Status: RECRUITING
Conditions: Appetitive Behavior
Interventions: OTHER: Phase 1 Control|OTHER: Phase 2 High Fibre Weight Loss|OTHER: Phase 3 High Fibre and Non-Nutritive Sweetener Weight Loss
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: (PM-01) IMPRIME PGG® With BTH1704 and Gemcitabine for Advanced Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: BTH1704|DRUG: IMPRIME PGG|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Minimal Hepatic Encephalopathy in Patients With Cirrhosis and Portal Hypertension
Status: RECRUITING
Conditions: Cirrhosis|Portal Hypertension
Interventions: DIAGNOSTIC_TEST: Assessment of Minimal hepatic encephalopathy (MHE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Personalized NK Cell Therapy in CBT
Status: RECRUITING
Conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Acute Biphenotypic Leukemia|Acute Lymphoblastic Leukemia|Acute Lymphoblastic Leukemia in Remission|Acute Myeloid Leukemia With Myelodysplasia-Related Changes|Acute Myeloid Leukemia With Variant MLL Translocations|B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1|Chemotherapy-Related Leukemia|Chronic Myelomonocytic Leukemia|Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements|ISS Stage II Plasma Cell Myeloma|ISS Stage III Plasma Cell Myeloma|Myelodysplastic Syndrome|Myelodysplastic Syndrome With Excess Blasts|Myelodysplastic Syndrome With Gene Mutation|Myelodysplastic/Myeloproliferative Neoplasm|Previously Treated Myelodysplastic Syndrome|Recurrent Acute Myeloid Leukemia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Hodgkin Lymphoma|Recurrent Non-Hodgkin Lymphoma|Refractory Acute Lymphoblastic Leukemia|Refractory Adult Acute Lymphoblastic Leukemia|Secondary Acute Myeloid Leukemia|Therapy-Related Myelodysplastic Syndrome
Interventions: BIOLOGICAL: Allogeneic Natural Killer Cell Line NK-92|BIOLOGICAL: Anti-Thymocyte Globulin|DRUG: Busulfan|DRUG: Clofarabine|DRUG: Cyclophosphamide|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan|BIOLOGICAL: Rituximab|RADIATION: Total-Body Irradiation|PROCEDURE: Umbilical Cord Blood Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impacts of Touch-massage on the Experience of Patients With Chronic Pain: a Mixed Study.
Status: COMPLETED
Conditions: Chronic Pain
Interventions: OTHER: Toucher Massage (TM) on the feet|OTHER: Homedics HM MP RELEX 90 device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Minimal Extracorporeal Circuits (MECC) in Cardiac Surgery Procedures
Status: COMPLETED
Conditions: Postoperative Bloodloss
Interventions: DEVICE: MECC|DEVICE: MOPS|DEVICE: Super MOPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Biological Therapies Following Combination Chemotherapy and Bone Marrow or Peripheral Stem Cell Transplantation in Women With Stage II or Stage III Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: recombinant interferon gamma|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: thiotepa|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Project UPLIFT for Psychogenic Non-Epileptic Seizures
Status: COMPLETED
Conditions: Psychogenic Non-Epileptic Seizure|Depression|Non-Epileptic Seizure|Psychogenic Seizure
Interventions: BEHAVIORAL: Project UPLIFT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Single Therapy Versus Double and Triple Therapy of the Pellevé™ Wrinkle Treatment System for the Treatment of Moderate Facial Wrinkles
Status: COMPLETED
Conditions: Appearance of Facial Wrinkles
Interventions: DEVICE: Pelleve Wrinkle Treatment System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alveolar Ridges Expansion Using Osseodensification Versus Screw Expansion Technique
Status: COMPLETED
Conditions: Dental Implant Failed|Bone Fracture|Bone Infection
Interventions: DEVICE: Screw expander|DEVICE: Osseodensification drills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Home-Use Photobiomodulation Device for the Treatment of Patients With Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Standard treatment + Active B-Cure laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COREG MR Versus TOPROL-XL On Reduction Of Microalbuminuria In Patients With Hypertension And Microalbuminuria
Status: TERMINATED
Conditions: Heart Failure, Congestive and Microalbuminuria
Interventions: DRUG: metoprolol xl|DRUG: carvedilol MR|DRUG: lisinopril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Reciprocal Electrical Stimulation Versus Kinesio Taping
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DEVICE: electrical stimulation device|OTHER: kinesio taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Adverse Reactions Related to Immune Checkpoint Inhibitor in NSCLC Patients
Status: UNKNOWN
Conditions: Adverse Reactions|Immune Checkpoint Inhibitor|Non-Small Cell Lung Cancer Patients|Cardiac Event
Interventions: DRUG: renin-angiotensin system inhibitors or angiotensin-receptor-neprilysin inhibitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Study of The Treatment of Postoperative Adjuvant Apatinib vs. TACE in Hepatocellular Carcinoma Patients
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Apatinib|DRUG: Chemotherapy drugs+Iodized oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diuretic Versus Placebo in Pulmonary Embolism
Status: UNKNOWN
Conditions: Pulmonary Embolism With Right Ventricle Enlargement
Interventions: DRUG: Diuretics : Furosemide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conventional Versus RF Needle Transseptal Puncture for Cryoballoon Ablation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Baylis transseptal system group|DEVICE: Standard conventional transseptal group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Steroid Pulse Therapy in Acute Exacerbation of Idiopathic Pulmonary Fibrosis (AE-IPF) Admitted in ER
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis With Acute Exacerbation
Interventions: DRUG: Routine steroid administration group|DEVICE: Steroid pulse therapy group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: VR to Improve CINV, Sleep and Pain Among Children With Cancer in HK
Status: NOT_YET_RECRUITING
Conditions: Neoplasms|Child|Nausea|Vomiting|Sleep Hygiene|Pain
Interventions: DEVICE: Hypnosis VR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capnometry-Assisted Breathing Training for COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Capnometry-Assisted Training for COPD to Slow the Breath (CATCH)|DEVICE: Pulmonary Rehabilitation (PR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Catheter Associated Lower Urinary Infections Using the Oxys Indwelling Catheter
Status: UNKNOWN
Conditions: Urinary Infections
Interventions: DEVICE: Oxys Catheter|DEVICE: Covidien Mona-Therm Foley catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Nonsteroidal Anti-inflammatory Drug (NSAID) on Inflammatory Lesion of Axial Spondyloarthritis
Status: COMPLETED
Conditions: Spondylarthropathies|Magnetic Resonance Imaging
Interventions: DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Intervention to Improve Antenatal Access to CD4 Testing and HAART in Botswana
Status: COMPLETED
Conditions: HIV Infection|Pregnancy
Interventions: OTHER: Tokafatso programmatic intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Methylprednisolone After Total Hip Arthroplasty
Status: COMPLETED
Conditions: LOS|Postoperative Pain|Postoperative Nausea and Vomiting|Sleeping Quality|Fatigue|Inflammatory Response
Interventions: DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-damaging Retinal Laser Therapy With PASCAL Laser for Macular Diseases
Status: UNKNOWN
Conditions: Diabetic Macular Edema|Branch Retinal Vein Occlusion|Chronic Central Serous Retinopathy|Macular Telangiectasia
Interventions: PROCEDURE: Topcon Endpoint Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transfer of Genetically Engineered Lymphocytes in Melanoma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: BIOLOGICAL: Dose 1|BIOLOGICAL: Dose 2|BIOLOGICAL: Dose 3|BIOLOGICAL: Dose 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human Relaxin (rhRlx) in Pregnant Women Scheduled for Induction of Labor
Status: COMPLETED
Conditions: Labor, Induced
Interventions: DRUG: Serelaxin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Cefditoren Pivoxil Versus Ciprofloxacin in Acute Uncomplicated Cystitis
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DRUG: cefditoren pivoxil|DRUG: Ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dabigatran Treatment Following Transient Ischemic Attack and Minor Stroke
Status: COMPLETED
Conditions: Transient Ischemic Attack|Minor Ischemic Stroke
Interventions: DRUG: Dabigatran 110/150 mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kinetics of IgE Memory B Cells, Plasmablasts and Plasma Cells After Whole Lung Allergen Challenge in Mild Asthmatics
Status: COMPLETED
Conditions: Atopic Asthma
Interventions: PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Tonsil Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: PET-imaging of Unruptured Intracranial Aneurysm Inflammation
Status: UNKNOWN
Conditions: Intracranial Aneurysm|Cerebral Aneurysm|Inflammation
Interventions: RADIATION: PET imaging, 18F-FDG|RADIATION: PET imaging, 68Ga-DOTANOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effectiveness of Prolotherapy (%5 Dextros) in the Treatment of Patients With Chondromalacia Patella
Status: COMPLETED
Conditions: Chondromalacia Patellae
Interventions: PROCEDURE: Dextrose Prolotherapy|PROCEDURE: Serum Physiological Group (placebo control group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT