pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cataract Surgery vs Cataract Surgery With ECPL for Treatment of Plateau Iris Configuration or Syndrome
Status: COMPLETED
Conditions: Glaucoma
Interventions: PROCEDURE: Phacoemulsification|PROCEDURE: Endoscopic Cycloplasty (ECPL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Triple Therapy in Patients on Oral Anticoagulation After Drug Eluting Stent Implantation
Status: UNKNOWN
Conditions: Coronary Artery Disease|Atrial Fibrillation
Interventions: DRUG: aspirin|DRUG: clopidogrel|DRUG: oral anticoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FMT for Post-infectious IBS
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: BIOLOGICAL: Fecal transplantation|DRUG: OTILONII BROMIDUM|DIETARY_SUPPLEMENT: multi-strain probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab +Bevacizumab+pc for Untreated EGFR+ and High PD-L1 Non-squamous NSCLC
Status: UNKNOWN
Conditions: Non-squamous Non-small Cell Lung Cancer|EGFR Gene Mutation
Interventions: DRUG: Tislelizumab Combined With Bevacizumab and Platinum Plus Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Geminin and Mcm-2 in Prognosis of Renal Cell Carcinoma
Status: UNKNOWN
Conditions: Renal Cell Carcinoma
Interventions: DIAGNOSTIC_TEST: Immunohistochemistry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Operational Evaluation of a Photic Countermeasure to Improve Alertness, Performance, and Mood During Nightshift Work on a 105-day Simulated Human Exploration Mission to Mars
Status: COMPLETED
Conditions: Sleep|Alertness|Fatigue
Interventions: DEVICE: Bright Light Box
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of CoSeal on Bleeding & Adhesions in Pediatric Heart Surgery
Status: COMPLETED
Conditions: Congenital Heart Defect|Surgery-Induced Tissue Adhesions|Hemorrhage
Interventions: DEVICE: CoSeal Surgical Spray Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of SGLT2 Inhibitor on Hemodynamic Parameters in Resistant Hypertensive Subjects
Status: COMPLETED
Conditions: Hypertension|Diabetes Mellitus, Type 2|Blood Pressure|Obesity|Cardiac Hypertrophy|Microalbuminuria|Vascular Stiffness
Interventions: DRUG: Dapagliflozin 10mg|DRUG: Glibenclamide 5Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Insulin Glulisine vs Regular Human Insulin on Postprandial Endothelial Function in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Insulin Glulisine|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prepackaged Nutritional Formulations Versus Restricted Diet for Bowel Preparation
Status: UNKNOWN
Conditions: Bowel Preparation
Interventions: OTHER: prepackaged semisolid nutritional formulations|OTHER: restricted diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Radial Forearm Donor Site Closure
Status: RECRUITING
Conditions: Oral Cancer|Oral Cavity Cancer|Donor Site Complication
Interventions: PROCEDURE: Split-Thickness Skin Graft for Radial Forearm Donor Site Closure|PROCEDURE: Hatchet Flap for Radial Forearm Donor Site Closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Efficacy Study of MsChief Personal Lubricant in Healthy Female Subjects
Status: COMPLETED
Conditions: Healthy Females
Interventions: DEVICE: MsChief Classic Natural Lubricant|DEVICE: MsChief Ylang Ylang Natural Lubricant|DEVICE: MsChief Vanilla & Citrus Natural Lubricant|DEVICE: MsChief Tea & Peach Natural Lubricant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vapocoolant Spray Application During Intraarticular Knee Injection
Status: RECRUITING
Conditions: Osteo Arthritis Knee|Injection Site Discomfort|Injection Fear
Interventions: OTHER: Topical Cooling Spray|OTHER: Saline spray as Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase II Study of HMPL-004 in Subjects With Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: HMPL-004|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect on Vascular Calcification of Replacing Warfarin by Rivaroxaban With or Without VitK2 in Hemodialysis Patients
Status: COMPLETED
Conditions: Vascular Calcification
Interventions: DRUG: rivaroxaban|DIETARY_SUPPLEMENT: Vitamin K2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Rotigotine Patch in Adolescent Subjects With Restless Legs Syndrome of Unknown Cause
Status: TERMINATED
Conditions: Restless Legs Syndrome
Interventions: DRUG: Rotigotine 1 milligram/24 hours|DRUG: Rotigotine 2 milligram/24 hours|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of BEMA™ Fentanyl in the Treatment of Breakthrough Pain in Cancer Subjects
Status: COMPLETED
Conditions: Pain|Cancer
Interventions: DRUG: BEMA™|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Aligner Wear Time and Change Frequency
Status: UNKNOWN
Conditions: Adjunctive Usage of Vibrational Therapy|Dental Monitoring Accuracy
Interventions: DEVICE: Dental Monitoring assisted aligner change, 12-hour tray wear time and VPro+ are the interventions for the trial.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutrition in Rheumatic Diseases
Status: RECRUITING
Conditions: Spondyloarthritis|Rheumatoid Arthritis|Polyarthritis
Interventions: DIETARY_SUPPLEMENT: Omega-3|DIETARY_SUPPLEMENT: Placebo (soya)|BEHAVIORAL: Dietary guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Radiotherapy and Pembrolizumab in People With Adrenocortical Carcinoma
Status: RECRUITING
Conditions: Adrenocortical Carcinoma|ACC|Metastatic Adrenocortical Carcinoma
Interventions: RADIATION: Ablative Radiotherapy|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brief Intervention to Prevent Alcohol Socialization (BIPAS Alcohol)
Status: RECRUITING
Conditions: Alcohol Drinking, Adolescent|Drinking Behavior|Drinking, Alcohol|Adolescent Behavior
Interventions: BEHAVIORAL: BIPAS Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase I/II Trial of Doxil and Hyperthermia for Breast Cancer Patients With Chest Wall Recurrence or Stage IV Disease With Locally Advanced Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Doxil|PROCEDURE: heat treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Pediatric Safety and Pharmacokinetics Study of Ha44 Gel Administered Topically for Treatment of Head Lice Infestation
Status: COMPLETED
Conditions: Head Lice Infestation
Interventions: DRUG: Ha44 Gel 0.74% w/w
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dosimetric Limitation of Pelvic Bone and Peritoneal Space in Rectal Cancer Patients During Chemoradiotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Rectal Cancer
Interventions: RADIATION: dosimetric limitation of pelvic bone and peritoneal space during radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Journey Ahead: Enhancing Coping and Communication for Women Diagnosed With Gynecological Cancer
Status: RECRUITING
Conditions: Gynecologic Cancer|Ovarian Cancer|Endometrial Cancer|Fallopian Tube Cancer|Cervical Cancer|Uterine Cancer
Interventions: OTHER: Informational intervention|OTHER: survey administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Camrelizumab Combined With Chemotherapy ± Thalidomide in First-line Treatment of Patients With Advanced Non-small Cell Lung Cancer (NSCLC)
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer|Camrelizumab
Interventions: DRUG: Camrelizumab + chemotherapy+Thalidomide|DRUG: Camrelizumab + chemotherapy+placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Community Health Worker Program to Support Rural Older Adults
Status: COMPLETED
Conditions: Frail Elderly|Cognitive Impairment|Mobility Limitation|Depressive Symptoms
Interventions: BEHAVIORAL: Tai Ji Quan: Moving for Better Balance|BEHAVIORAL: Behavioral Activation|OTHER: Resource Navigation|OTHER: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Single Dose Study of Tamiflu in Volunteers in Dialysis And in Volunteers With Reduced Creatinine Clearance
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Tamiflu (oseltamivir)|DRUG: Tamiflu (oseltamivir)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Caspofungin for Invasive Pulmonary Aspergillosis Underlying Chronic Obstructive Pulmonary Disease
Status: UNKNOWN
Conditions: Invasive Pulmonary Aspergillosis|Chronic Obstructive Pulmonary Disease
Interventions: DRUG: caspofungin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Improvement After Ultrasound Guided Continuous Radio Frequency 60 Degree for Plantar Fasciitis
Status: RECRUITING
Conditions: Plantar Fascitis
Interventions: PROCEDURE: ultrasound guided 60 degree CRF for plantar fasciitis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two phosphAte taRGets in End-stage Renal Disease Trial (TARGET)
Status: COMPLETED
Conditions: End-stage Renal Disease
Interventions: DRUG: Calcium carbonate ( Intensive phosphate control)|DRUG: Calcium carbonate (Liberalized phosphate control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ceftobiprole in the Treatment of Patients With Staphylococcus Aureus Bacteremia
Status: COMPLETED
Conditions: Staphylococcus Aureus Bacteremia
Interventions: DRUG: Ceftobiprole medocaril|DRUG: Daptomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allopurinol Improves Heart Function in African Americans With Resistant Hypertension
Status: RECRUITING
Conditions: Heart Failure Preserved Ejection Fraction|Resistant Hypertension
Interventions: DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ucha-Shinki-Hwan on Korean Patients With Cold Hypersensitivity in the Hands and Feet-Double Blinded, Randomized, Multicenter, Placebo Controlled Clinical Trial
Status: COMPLETED
Conditions: Cold Hypersensitivity
Interventions: DRUG: Ucha-Shinki-Hwan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Compare Nintedanib With Placebo for Patients With Scleroderma Related Lung Fibrosis
Status: COMPLETED
Conditions: Scleroderma, Systemic
Interventions: DRUG: Nintedanib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and Cisplatin Plus Radiation Therapy Followed by Filgrastim in Treating Patients With Recurrent Head and Neck Cancer or Lung Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Lung Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Zika Virus Purified Inactivated Vaccine (ZPIV) Accelerated Vaccination Schedule Study
Status: COMPLETED
Conditions: Zika
Interventions: BIOLOGICAL: Zika Virus Purified Inactivated Vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of a Sub-symptom Threshold Aerobic Exercise Program on Recovery in Concussed Athletes
Status: UNKNOWN
Conditions: Concussion, Mild|Rehabilitation
Interventions: OTHER: Aerobic Exercise|OTHER: Placebo/Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Minto Model in Effect Site Mode for Target-Controlled Infusion of Remifentanil During Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Anesthetics, Intravenous|Pharmacology|Anesthetics|Cardiopulmonary Bypass
Interventions: DRUG: Remiva|DRUG: Ultiva
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab With or Without Stem Cell Transplant in Treating Patients With Minimal Residual Disease-Negative Mantle Cell Lymphoma in First Complete Remission
Status: RECRUITING
Conditions: CD20 Positive|Mantle Cell Lymphoma
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib to Treat Children and Young Adults With Neurofibromatosis Type 1 and Inoperable Plexiform Neurofibromas
Status: COMPLETED
Conditions: Neurofibromatosis Type I|Plexiform Neurofibroma
Interventions: DRUG: Nexavar (BAY 43-9006) (Sorafenib)|DRUG: Toxicity, Pharmacokinetics|DRUG: Pharmacodynamics|DRUG: Radiographic Evaluation|DRUG: QOL assessment, Neuropsychological|DRUG: Bony Toxicity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI-Guided Laser Surgery and Doxorubicin Hydrochloride in Treating Patients With Recurrent Glioblastoma Multiforme
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DEVICE: MRI-guided Laser Heat Ablation (MLA)|DRUG: Doxorubicin|OTHER: Blood draw - dendritic cells|DEVICE: Dynamic Susceptibility Contrast Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of Zoenasa® Versus Mesalamine Enema in Subjects With Left-Sided Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis|Left-sided Ulcerative Colitis|Distal Ulcerative Colitis
Interventions: DRUG: Zoenasa-1:4|DRUG: Mesalamine Enema
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Dehydroepiandrosterone (DHEA) in Postmenopausal Breast Cancer Survivors on Aromatase Inhibitors
Status: TERMINATED
Conditions: Vaginal Atrophy|Postmenopausal Symptoms|Breast Cancer Female|Long-term Survivors
Interventions: DRUG: Vaginal Dehydroepiandrosterone|COMBINATION_PRODUCT: Vaginal Polycarbophil Moisturizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Surgical Revascularization Outcomes After Oral Anticoagulation or Antiplatelets
Status: UNKNOWN
Conditions: Coronary Artery Disease|Saphenous Vein Graft Patency
Interventions: DRUG: Rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of 5% VVN001 Ophthalmic Solution in Dry Eye Disease
Status: NOT_YET_RECRUITING
Conditions: Dry Eye
Interventions: DRUG: VVN001 Ophthalmic Solution, 5%|DRUG: VVN001 Ophthalmic Solution, Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of AZD9833 in Japanese Women With ER Positive, HER2 Negative Advanced Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: ER+ HER2- Advanced Breast Cancer
Interventions: DRUG: AZD9833
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Non-invasive Brain Stimulation Techniques for Lower Limb Recovery in Stroke Patients
Status: TERMINATED
Conditions: Stroke
Interventions: PROCEDURE: conventional rehab training|DEVICE: tDCS|DEVICE: rTMS|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opioid Use After Laparoscopic Salpingectomy
Status: RECRUITING
Conditions: Opioid Use|Post-operative Pain|Sterility, Female
Interventions: DRUG: Acetaminophen|DRUG: Ibuprofen|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Acute Red Raspberry Consumption on Post-prandial Oxidative Stress
Status: COMPLETED
Conditions: Oxidative Stress|Antioxidants
Interventions: DIETARY_SUPPLEMENT: red raspberries|DIETARY_SUPPLEMENT: bread controls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: 20-valent Pneumococcal Conjugate Vaccine Safety and Immunogenicity Study in Pneumococcal Vaccine-Naïve Adults 60 Years of Age and Older in Japan, Korea, and Taiwan
Status: COMPLETED
Conditions: Pneumococcal Disease
Interventions: BIOLOGICAL: 20vPnC|OTHER: Saline|BIOLOGICAL: 13vPnC|BIOLOGICAL: PPSV23
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Hematological Parameters in Axial Spondyloarthritis
Status: RECRUITING
Conditions: Ankylosing Spondylitis
Interventions: OTHER: Systemic inflammatory index|OTHER: BASDAI|OTHER: ASDAS-ESR|OTHER: ASDAS-CRP|OTHER: MASES
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acute Effects of Different Protein Sources and Different Glycemic Index on Energy Balance, Glucose Allostasis and Amino Acid Metabolism: a Randomized, 4-condition, Two Cross-over Study in Adults.
Status: COMPLETED
Conditions: Overweight
Interventions: OTHER: Fish and carbohydrats with low or high GI|OTHER: Veal and carbohydrats with low or high GI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Liposomal Bupivacaine in Vaginal Hysterectomy
Status: TERMINATED
Conditions: Vaginal Hysterectomy
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Management of Common Bile Duct (CBD) Stones at Laparoscopic Cholecystectomy
Status: TERMINATED
Conditions: Choledocholithiasis|Cholelithiasis
Interventions: PROCEDURE: Transcystic Stenting (Facilitated ERCP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: ECT
Clinical trial: Angelman Syndrome (AS) Biomarker Study
Status: COMPLETED
Conditions: Angelman Syndrome|Chromosome 15q Duplication (dup15q) Syndrome
Interventions: PROCEDURE: Lumbar Puncture|PROCEDURE: Blood Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of the Oral Farnesoid X Receptor Modulator EYP001a to Assess Its Safety and Anti-viral Effect in Chronic Hepatitis B Patients in Combination With Pegylated Interferon alpha2a Alone and With Entecavir
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: EYP001a|DRUG: Entecavir|DRUG: Pegylated interferon alpha2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of 5-ALA Photodynamic Therapy and CO2 Laser for Treating Persistent Low-Grade Cervical Lesions With High-Risk HPV Infection
Status: RECRUITING
Conditions: HPV-Related Cervical Carcinoma|Low-Grade Squamous Intraepithelial Lesions|HPV Infection|Photodynamic Therapy
Interventions: PROCEDURE: CO2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: LAS41008 in Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: LAS41008|DRUG: LASW1835|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extrapleural Intercostal Catheter vs. Thoracic Epidural for Thoracotomy Pain
Status: TERMINATED
Conditions: THoracotomy
Interventions: PROCEDURE: Thoracic Epidural|PROCEDURE: Extrapleural Intercostal Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Feasibility and Utility of Artificial Intelligence (AI) / Machine Learning (ML) - Driven Advanced Intraoperative Visualization and Identification of Critical Anatomic Structures and Procedural Phases in Laparoscopic Cholecystectomy
Status: RECRUITING
Conditions: Cholecystitis|Cholelithiasis|Biliary Dyskinesia
Interventions: DEVICE: ICG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Trial to Evaluate the Effect of Itraconazole and Rifampicin on ABSK021
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Part A ABSK201 and Itraconazole|DRUG: Part A ABSK201 and Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NMDA Receptor Antagonist Nitrous Oxide Targets Affective Brain Circuits
Status: TERMINATED
Conditions: Depressive Disorder, Major|Depressive Disorder, Treatment-Resistant
Interventions: DRUG: Nitrous Oxide|DRUG: Placebo gas|DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abdominal Ice Packs for Pain Control and Reduction of Narcotic Use Following Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Pain, Postoperative|Hysterectomy|Narcotic Use|Cryotherapy Effect
Interventions: PROCEDURE: Ice packs plus usual post-op analgesia|OTHER: Usual post-op analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Assessment and Treatment for TMD
Status: RECRUITING
Conditions: Temporomandibular Joint Disorders|Orofacial Pain
Interventions: BEHAVIORAL: Cognitive-Behavioral Treatment|BEHAVIORAL: Individualized Assessment and Treatment Program|OTHER: Standard Conservative Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the Investigational Device, SurgiShield Anti-Adhesion Barrier Gel
Status: COMPLETED
Conditions: Wound Healing
Interventions: DEVICE: 5ml surgishield
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety, Tolerability, and Efficacy of SM04690 Injected in the Target Knee Joint of Moderately to Severely Symptomatic Osteoarthritis Subjects
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: SM04690|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Medication-overuse Headache: The Effect of a Patient Educational Programme as an add-on to Standard Treatment
Status: COMPLETED
Conditions: Secondary Headache Disorders|Medication-overuse Headache
Interventions: BEHAVIORAL: Educational programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Surgically Induced Astigmatism of Temporal Versus Nasal Clear Corneal Phacoemulsification
Status: COMPLETED
Conditions: Surrgical Induced Astigmatism
Interventions: PROCEDURE: phacoemulsification and intraocular lens implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Nicotinamide Riboside on Metabolism and Vascular Function
Status: COMPLETED
Conditions: Aging|Lipemia
Interventions: DIETARY_SUPPLEMENT: Nicotinamide riboside chloride (Niagen)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Dapagliflozin for the Hospital Management of Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type2diabetes|Coronary Artery Disease
Interventions: DRUG: Dapagliflozin|DRUG: Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research on Benefit of Umooze as Add- on Therapy in Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DIETARY_SUPPLEMENT: Umooze|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Augmenting a Post-Stroke Wellness Program With Respiratory Muscle Training
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: Exercise Program + Respiratory Strength Training|OTHER: Exercise Program + Respiratory Relaxation Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Intravenous to Oral Solithromycin (CEM-101) Compared to Intravenous to Oral Moxifloxacin in Treatment of Patients With Community-Acquired Bacterial Pneumonia
Status: COMPLETED
Conditions: Community-acquired Bacterial Pneumonia
Interventions: DRUG: Solithromycin|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Alimta (Pemetrexed) Treatment of Advanced Thymoma and Thymic Carcinoma
Status: COMPLETED
Conditions: Thymoma|Thymic Carcinoma
Interventions: DRUG: Premetrexed (Alimta)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acquired Pyruvate Kinase Deficiency In Clonal Myeloid Neoplasms
Status: RECRUITING
Conditions: Pyruvate Kinase Deficiency|Pyruvate Kinase Deficiency Anemia|Hereditary Hemolytic Anemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasm|Clonal Myeloid Neoplasm|Myeloproliferative Neoplasm|Acute Myeloid Leukemia|Clonal Cytopenia of Undetermined Significance|Other Clonal Myeloid Neoplasm|Unexplained Coombs-negative Non-immune Hemolytic Anemia
Interventions: PROCEDURE: Blood Draw
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Different Plane Blocks on Quality of Recovery and Postoperative Pain After Laparoscopic Hysterectomy
Status: RECRUITING
Conditions: Post Operative Pain
Interventions: PROCEDURE: TAP block|PROCEDURE: ESP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of Plozasiran in Adults With Hypertriglyceridemia
Status: RECRUITING
Conditions: Hypertriglyceridemia
Interventions: DRUG: Plozasiran Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin C Infusion for the Treatment of Severe 2019-nCoV Infected Pneumonia
Status: TERMINATED
Conditions: Vitamin C|Pneumonia, Viral|Pneumonia, Ventilator-Associated
Interventions: DRUG: VC|DRUG: Sterile Water for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Limited-efficacy Testing of Spring Distraction System (SDS) and Unilateral One-way Rod (MID-C) for Early Onset Scoliosis
Status: WITHDRAWN
Conditions: Early-Onset Scoliosis Deformity of Spine (Disorder)|Idiopathic Scoliosis
Interventions: DEVICE: SDS|DEVICE: MID-C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy and Sargramostim With or Without Docetaxel in Treating Patients With Metastatic Lung Cancer or Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Extensive Stage Small Cell Lung Cancer|Recurrent Colon Cancer|Recurrent Non-small Cell Lung Cancer|Recurrent Rectal Cancer|Recurrent Small Cell Lung Cancer|Stage IV Colon Cancer|Stage IV Non-small Cell Lung Cancer|Stage IV Rectal Cancer
Interventions: DRUG: recombinant fowlpox-CEA(6D)/TRICOM vaccine|DRUG: recombinant vaccinia-CEA(6D)-TRICOM vaccine|DRUG: docetaxel|DRUG: sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ASP2215 in Combination With Erlotinib in Subjects With Epidermal Growth Factor Receptor (EGFR) Activating Mutation-Positive (EGFRm+) Advanced Non-Small-Cell Lung Cancer (NSCLC) Who Have Acquired Resistance to an EGFR Tyrosine Kinase Inhibitor (TKI)
Status: TERMINATED
Conditions: Non-Small-Cell Lung Cancer
Interventions: DRUG: Gilteritinib|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IDEA-033 Open Label Study
Status: COMPLETED
Conditions: Joint Pain|Musculoskeletal Pain|Stiffness|Soft Tissue Inflammation in Designated Target Area(s)
Interventions: DRUG: IDEA-033
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization of Focal Liver Lesions by Real-Time Contrast-Enhanced Ultrasound Imaging (CEUS)
Status: COMPLETED
Conditions: Focal Liver Lesions|Liver Cancer|Liver Cirrhosis
Interventions: PROCEDURE: Real-time contrast-enhanced ultrasound sonography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Intravitreal Injection of Human Retinal Progenitor Cells in Adults With Retinitis Pigmentosa
Status: COMPLETED
Conditions: Retinitis Pigmentosa
Interventions: BIOLOGICAL: human retinal progenitor cells|OTHER: Mock injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcome of Regenerative Endodontic Procedure and Root Canal Treatment for the Management of Apical Periodontitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Apical Periodontitis
Interventions: PROCEDURE: Root canal treatment|PROCEDURE: Regenerative endodontic procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mesothelioma Stratified Therapy (MiST) : A Multi-drug Phase II Trial in Malignant Mesothelioma
Status: ACTIVE_NOT_RECRUITING
Conditions: Mesothelioma, Malignant
Interventions: DRUG: Rucaparib|DRUG: Abemaciclib|DRUG: pembrolizumab & bemcentinib|DRUG: Atezolizumab & Bevacizumab|DRUG: Dostarlimab and Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of Immunological Assays for the Evaluation of Tumor Antigen Specific Immunity
Status: COMPLETED
Conditions: Ovarian Serous Adenocarcinoma|Undifferentiated Carcinoma of Ovary|Cervical Cancer|Cervical Intraepithelial Neoplasia, Grade 3|Acute Myeloid Leukemia|Chronic Myeloid Leukemia
Interventions: PROCEDURE: Blood Sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Precision Optical Guidance for Oral Biopsy
Status: RECRUITING
Conditions: Oral Lesions
Interventions: DEVICE: High Resolution Microendoscope (HRME)|DEVICE: Optical Mapping Scope|DRUG: Proflavine hemisulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Investigate the Safety and Duration of Effect of Different Botulinum Toxin A (NT 201) Dose Groups Following the Treatment of Glabellar Frown Lines
Status: COMPLETED
Conditions: Moderate to Severe Glabellar Frown Lines
Interventions: DRUG: NT 201
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PNF and Gait Training on Balance and Gait in Diabetic Neueopathy Patients
Status: COMPLETED
Conditions: Diabetic Neuropathies
Interventions: OTHER: Pnf exercises|OTHER: Gait training exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Joint Effort 2.0: a Mobile Application With University Students
Status: RECRUITING
Conditions: Cannabis Use|Cannabis|Cannabis Dependence|Cannabis Smoking|Cannabis Use, Unspecified
Interventions: OTHER: Joint Effort|OTHER: Brief normative feedback and standard information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Combined Pentoxifylline-tocopherol-clodronate vs Placebo in Radiation-induced Brachial Plexopathy
Status: COMPLETED
Conditions: Radiation Induced Brachial Plexopathy
Interventions: DRUG: Pentoxifylline placebo|DRUG: Pentoxifylline|DRUG: Tocopherol acetate|DRUG: Clodronic Acid|DRUG: Tocopherol placebo|DRUG: Clodronate placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Longer-term Adrenal Suppression Using Low Dose Hydrocortisone on Androgen Overproduction
Status: WITHDRAWN
Conditions: Hyperandrogenemia|Obesity|Polycystic Ovary Syndrome
Interventions: DRUG: Hydrocortisone|DRUG: dexamethasone|DRUG: Cosyntropin|DRUG: rhCG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Bacterial Vaginosis (BV) With Tinidazole
Status: COMPLETED
Conditions: Bacterial Vaginosis
Interventions: DRUG: tinidazole, metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Norepinephrine Versus Phenylephrine Continuous Variable Infusion in Cesarean Delivery
Status: COMPLETED
Conditions: Cesarean Section Complications|Spinal Anesthesia
Interventions: DRUG: Phenylephrine|DRUG: Norepinephrine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of the Overstich Technique for the Management of Weight Regain After Gastric Bypass.
Status: TERMINATED
Conditions: the Management of Weight Regain After Gastric Bypass by Endoscopic Suturing
Interventions: DEVICE: Regular endoscopy + endogastric suturing|DIAGNOSTIC_TEST: Regular endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Sacral Nerve Stimulation in Children and Adolescents With Chronic Constipation
Status: COMPLETED
Conditions: Chronic Constipation With Overflow|Encopresis With Constipation and Overflow Incontinence|Hirschprung's Disease|Anorectal Malformations
Interventions: DEVICE: Non-invasive Neuromodulation|OTHER: Medical and Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VExUS-guided Fluid Management in Patients With Acute Kidney Injury in the Intensive Care Unit
Status: UNKNOWN
Conditions: Acute Kidney Injury|Renal Insufficiency, Acute|Kidney; Disease, Acute|Critical Illness|Volume Overload|Fluid Overload
Interventions: DIAGNOSTIC_TEST: VExUS Score
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evorpacept (ALX148) in Combination With Pembrolizumab and Chemotherapy in Patients With Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-04)
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer|Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: evorpacept|DRUG: pembrolizumab|DRUG: Cisplatin/Carboplatin; 5FU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal (IP) Cisplatin Given With Paclitaxel to Treat Epithelial Ovarian Cancer
Status: TERMINATED
Conditions: Epithelial Ovarian Cancer
Interventions: DRUG: Intraperitoneal (IP) Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immersive Virtual Reality for Chronic Neuropathic Pain After Spinal Cord Injury: A Feasibility Trial
Status: COMPLETED
Conditions: Neuralgia|Spinal Cord Injuries|Chronic Pain
Interventions: DEVICE: Somatic IVR (sIVR)|DEVICE: Distractive IVR (dIVR)|DEVICE: Control IVR (cIVR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRECEDE-PROCEED Model-based Program on Genital Hygiene Behaviors
Status: COMPLETED
Conditions: Genital Infection Female
Interventions: BEHAVIORAL: Precede-Proceed based Training Program on Genital Hygiene Behaviors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Parasagittal Vs Cornerpocket Approaches
Status: NOT_YET_RECRUITING
Conditions: Supraclavicular Brachial Plexus Block
Interventions: PROCEDURE: supraclavicular ultrasound guided brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Bioequivalence Study of Bicalutamide 50 mg Tablet and Casodex 50 mg Tablet in Healthy Subjects Under Fasting Conditions
Status: COMPLETED
Conditions: Bioequivalency
Interventions: DRUG: Bicalutamide 50 mg Tablet vs Casodex® 50 mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, PK/PD, and Clinical Activity of KT-413 in Adult Patients With Relapsed or Refractory B-cell NHL
Status: SUSPENDED
Conditions: Non Hodgkin Lymphoma|Diffuse Large B Cell Lymphoma|DLBCL|MYD88 Gene Mutation
Interventions: DRUG: KT-413
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microcirculation Guided Therapy Versus "Standard Treatment" of Severe Sepsis
Status: UNKNOWN
Conditions: Severe Sepsis|Microcirculation
Interventions: DRUG: Dopamine|DRUG: dobutamine|DRUG: enoximone|DRUG: nitroglycerine|DRUG: noradrenaline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Robotic Hand Orthosis Providing Grasp Assistance for Patients With Brachial Plexus Injuries
Status: UNKNOWN
Conditions: Brachial Plexus Injury
Interventions: DEVICE: Exoskeleton glove
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Study to Evaluate the Effect of Roflumilast on Airway Inflammation and Function Following Allergen Challenge in Subjects With Allergic Asthma
Status: COMPLETED
Conditions: Allergic Asthma
Interventions: DRUG: Roflumilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Oral Zavegepant in Migraine Prevention
Status: TERMINATED
Conditions: Migraine
Interventions: DRUG: BHV-3500 (zavegepant)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transcranial Direct Current Stimulation for Post-stroke Gait Rehab
Status: COMPLETED
Conditions: Stroke|Gait Impairment
Interventions: OTHER: Active transcranial Direct Current Stimulation|OTHER: Sham transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of Aerosol Generation and Transport in the Human Lung of Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Exhaled particle analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics (PK) of Oral AZD6793 in Healthy and Chronic Obstructive Pulmonary Disease Participants, to Assess the Relative Oral Bioavailability Between Two Formulations, and the Food Effect on the PK of AZD6793 Compared to Fasting State.
Status: RECRUITING
Conditions: Inflammatory Diseases
Interventions: DRUG: AZD6793|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Probiotics Role in HPV Cervico-vaginal Infection Clearance
Status: COMPLETED
Conditions: Vaginal Infection|HPV Infection
Interventions: OTHER: Lactobacillus rhamnosus BMX 54, Lactobacillus reuteri RC-14, Lactobacillus rhamnosus GR-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pelvic Exenteration in Treating Patients With Recurrent Cervical Cancer
Status: COMPLETED
Conditions: Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Cervical Small Cell Carcinoma|Cervical Squamous Cell Carcinoma|Recurrent Cervical Carcinoma
Interventions: PROCEDURE: Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Thin Cp-EBUS Scope BF-UC290F for the Diagnosis of PPLs
Status: UNKNOWN
Conditions: Peripheral Pulmonary Nodules
Interventions: DEVICE: Linear Ultrasound Bronchoscope BF-UC290F (Olympus)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC