pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Spinal Ketorolac After Acute Opioid Exposure
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: ketorolac|DRUG: placebo|DRUG: remifentanil|DRUG: Capsaicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Identification of Immunogenic Neo-epitopes for the Development of Personalised Pancreatic Cancer Vaccines
Status: COMPLETED
Conditions: The Initial Aim of This Project is to Perform in Vitro Validation of Neoepitope Candidates Selected From Available Mutanome Data
Interventions: OTHER: Peptides
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Addressing Diabetes by Elevating Access to Nutrition
Status: RECRUITING
Conditions: Diabetes|Obesity|Lifestyle, Healthy
Interventions: BEHAVIORAL: Vida Sana (a Group Lifestyle Intervention)|BEHAVIORAL: Supplemental Healthy Food Deliveries
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation Study of the Effects of Sulphurous Water in the Treatment of Knee Osteoarthritis.
Status: COMPLETED
Conditions: KNEE OSTEOARTHRITIS
Interventions: OTHER: SULPHUROUS WATERS IMMERSION BATHS|OTHER: NOT SULPHUROUS WATERS IMMERSION BATHS|OTHER: CONTROL GROUP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of CB03-154 in Healthy Participants
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DRUG: CB03-154|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Work Activity Augmented by Cognitive Rehabilitation for Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: cognitive rehabilitation|PROCEDURE: work therapy|BEHAVIORAL: work therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib and Lenalidomide in Treating Patients With Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Previously Treated Myelodysplastic Syndrome|Refractory High Risk Myelodysplastic Syndrome|Secondary Myelodysplastic Syndrome|Therapy-Related Myelodysplastic Syndrome
Interventions: DRUG: Ibrutinib|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of the 5 Ways to Wellbeing Course Effects of the 5 Ways to Wellbeing Course
Status: RECRUITING
Conditions: Wellbeing|Quality of Life|Mental Health Wellness 1
Interventions: BEHAVIORAL: Five ways to wellbeing course
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Check and Support -Enhancing the Treatment of Hypertension in Outpatient Care, a Multicenter Study
Status: COMPLETED
Conditions: Hypertension|Blood Pressure|Patient Compliance|Patient Adherence|Medication Adherence
Interventions: BEHAVIORAL: IMB model-based initiation of antihypertensive medication|BEHAVIORAL: Tailored SMS-text message support|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Glucose Differences Between the Left Arm and Right Arm in Diabetic Patients Using a Continuous Glucose Monitor
Status: UNKNOWN
Conditions: Diabetes
Interventions: DIETARY_SUPPLEMENT: Supplement Consumption|DEVICE: Continuous Glucose Monitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PBMT in Providing Temporary Relief of Low Back Pain of Musculoskeletal Origin
Status: RECRUITING
Conditions: Low Back Pain
Interventions: DEVICE: Active PBMT|DEVICE: Placebo PBMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The ROAD 2.0 to Sustainable Medication Use: Redispensing Unused Oral Anticancer Drugs
Status: RECRUITING
Conditions: Cancer|Oncology|Pharmacy|Drug Prescriptions
Interventions: OTHER: redispensing oral anticancer drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ability of Aprepitant to Block Opioid Reward in Non-Dependent Opiate Abusers
Status: UNKNOWN
Conditions: Opioid-Related Disorders|Heroin Dependence|Substance-Related Disorders
Interventions: DRUG: aprepitant|DRUG: Pseudo-placebo - buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of Cabozantinib for the Treatment of Radioiodine (RAI)-Refractory Differentiated Thyroid Carcinoma (DTC) in the First-line Setting
Status: UNKNOWN
Conditions: Differentiated Thyroid Cancer (DTC)|Poorly Differentiated Thyroid Cancer
Interventions: DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study Called JOIHA to Learn More About How Well the Treatment With Jivi Works to Prevent Problems With Joints in Adults With Hemophilia A
Status: RECRUITING
Conditions: Hemophilia A|Prophylaxis of Bleeding
Interventions: DRUG: Damoctocog alfa pegol (Jivi, BAY94-9027)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exploring Novel Diagnostic Tools for Periprosthetic Joint Infection
Status: NOT_YET_RECRUITING
Conditions: Prosthesis-Related Infections|Arthroplasty, Replacement, Hip|Arthroplasty, Replacement, Knee
Interventions: DIAGNOSTIC_TEST: Reporter Gene Assay|DIAGNOSTIC_TEST: Flow Cytometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Two Fine Needle Biopsy Needles for Solid Pancreatic Masses
Status: COMPLETED
Conditions: Pancreatic Neoplasm
Interventions: DEVICE: Acquire EUS Biopsy Device|DEVICE: SharkCore Biopsy System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Dose Ranging Study With CHF 1531 in Subjects With Asthma (FLASH)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: CHF 1531 pMDI|DRUG: Formoterol Inhalation Solution|DRUG: Placebo pMDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Camera Capsule Endoscopy in the Routine Diagnostic Pathway for Colorectal Diseases
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: DIAGNOSTIC_TEST: CCE arm|DIAGNOSTIC_TEST: OC arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Combination PS-341 and Thalidomide in Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: PS-341|DRUG: Thalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implant Surface Decontamination in Peri-implantitis Treatment
Status: COMPLETED
Conditions: Peri-implantitis|Periodontal Disease
Interventions: PROCEDURE: placebo|PROCEDURE: Chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Single-nucleotide-polymorphism in Idiopathic Membranous Nephropathy
Status: UNKNOWN
Conditions: Idiopathic Membranous Nephropathy
Interventions: DRUG: The Comprehensive Treatment Regimen of Traditional Chinese Medicine|DRUG: The immunosuppressive agents
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antibody Conditioning Regimen For Allogeneic Donor Stem Cell Transplantation Of Patients With Fanconi Anemia
Status: TERMINATED
Conditions: Fanconi Anemia|Severe Aplastic Anemia
Interventions: BIOLOGICAL: CAMPATH-1H|BIOLOGICAL: Anti-CD45|DRUG: Fludarabine|PROCEDURE: Stem cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pivotal Study to Assess the InSpace™ Device for Treatment of Full Thickness Massive Rotator Cuff Tears
Status: COMPLETED
Conditions: Rotator Cuff Syndrome
Interventions: DEVICE: InSpace sub-acromial tissue spacer system|PROCEDURE: Partial repair of rotator cuff
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Physiologic Interactions Between the Adrenal- and the Parathyroid Glands
Status: COMPLETED
Conditions: Osteoporosis|Vitamin D Deficiency|Cardiovascular Disease
Interventions: DRUG: Valsartan|DRUG: Placebo Valsartan|DIETARY_SUPPLEMENT: Cholecalciferol|DIETARY_SUPPLEMENT: Placebo cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Gabapentin 800 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Gabapentin 800 mg tablets, single dose (1 tablet)|DRUG: NEURONTIN® 400 mg capsules, single dose (2 capsules)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Melatonin for Neuroprotection Following Perinatal Asphyxia
Status: COMPLETED
Conditions: Perinatal Asphyxia
Interventions: DRUG: Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of Naftifine Hydrochloride Cream 2% and Naftin® Cream 2% in Patients With Tinea Pedis
Status: COMPLETED
Conditions: Tinea Pedis
Interventions: DRUG: Naftifine Hydrochloride Cream 2%|DRUG: Naftin® (Naftifine Hydrochloride) Cream 2%|DRUG: Placebo Topical Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: (PIONEER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, Versus Placebo in Patients With Indolent Systemic Mastocytosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Indolent Systemic Mastocytosis
Interventions: DRUG: Avapritinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhibition of CArbonic Anhydrase in Combination With Platinum and Etoposide-based Radiochemotherapy in Patients With Localized Small Cell Lung Cancer
Status: RECRUITING
Conditions: Small Cell Lung Cancer
Interventions: DRUG: acetazolamide in combination with platinum and etoposide-based radiochemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of 2 Ovarian Stimulation Protocols for Women With Low Ovarian Reserve
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: Letrozole, Gonadotropins|DRUG: Gonadotropins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CDX-0159 in Patients With Chronic Inducible Urticaria
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Inducible Urticaria
Interventions: BIOLOGICAL: barzolvolimab|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azithromycin+Amoxicillin/Clavulanate vs Amoxicillin/Clavulanate in COVID19 Patients With Pneumonia in Non-intensive Unit
Status: UNKNOWN
Conditions: COVID-19 Pneumonia
Interventions: COMBINATION_PRODUCT: Azithromycin with amoxicillin/clavulanate|DRUG: amoxicillin/clavulanate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triheptanoin Treatment Trial for Patients With Adult Polyglucosan Body Disease
Status: COMPLETED
Conditions: Adult Polyglucosan Body Disease|Glycogen Brancher Enzyme Deficiency|Glycogen Storage Disease Type IV
Interventions: DRUG: Triheptanoin|OTHER: Vegetable Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic MRI-HIFU Ablation of Uterine Fibroids in a 3T MRI Scanner
Status: COMPLETED
Conditions: Uterine Leiomyomas
Interventions: DEVICE: Philips MR-guided HIFU system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer
Status: RECRUITING
Conditions: Prostate Adenocarcinoma|Stage I Prostate Cancer AJCC v8|Stage II Prostate Cancer AJCC v8|Stage IIA Prostate Cancer AJCC v8|Stage IIB Prostate Cancer AJCC v8|Stage IIC Prostate Cancer AJCC v8|Stage III Prostate Cancer AJCC v8|Stage IIIA Prostate Cancer AJCC v8|Stage IIIB Prostate Cancer AJCC v8|Stage IIIC Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8
Interventions: DRUG: Apalutamide|DRUG: Hormone Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Goal-Oriented Care Interventions
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Acute on Chronic Renal Failure|Acute Kidney Injury
Interventions: BEHAVIORAL: The Goal-Oriented Care program|BEHAVIORAL: The routine health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Convalescent Plasma to Limit SARS-CoV-2 Associated Complications
Status: COMPLETED
Conditions: SARS-CoV 2
Interventions: BIOLOGICAL: SARS-CoV-2 convalescent plasma|BIOLOGICAL: Plasma from a volunteer donor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Vadastuximab Talirine Given Prior to or After Allogeneic Hematopoietic Stem Cell Transplant in AML Patients
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Fludarabine|DRUG: Melphalan|DRUG: vadastuximab talirine|DRUG: vadastuximab talirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Gravity on Tracheal Colonization During Mechanical Ventilation in Infants
Status: COMPLETED
Conditions: Pneumonia, Ventilator-Associated
Interventions: BEHAVIORAL: supine positioning|BEHAVIORAL: lateral positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of QAX576 in Asthma Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: QAX576|DRUG: QAX576|DRUG: QAX576|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Mulligan and Maitland Techniques on Rotator Cuff Lesions
Status: COMPLETED
Conditions: Rotator Cuff Tears
Interventions: OTHER: conventional exercise program|OTHER: Mulligan application|OTHER: Maitland application|DEVICE: TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: An Electronic Health Record-based Approach to Increase PrEP Knowledge and Uptake: the EMC2 PrEP Strategy
Status: RECRUITING
Conditions: HIV Infections|Electronic Health Record|Primary Health Care
Interventions: BEHAVIORAL: EMC2 PrEP Educational Tool|BEHAVIORAL: Discrete Scheduling of a Dedicated PrEP Visit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Different Schedules of Functional Task Practice for Improving Hand and Arm Function After Stroke
Status: WITHDRAWN
Conditions: Cerebrovascular Accident|Hemiplegia
Interventions: BEHAVIORAL: functional task practice - distributed|BEHAVIORAL: functional task practice - condensed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: a Study to Evaluate Adhesion Risk in Fertility Patients' Status Post Laparoscopic Myomectomy.
Status: WITHDRAWN
Conditions: Uterine Fibroids|Infertility
Interventions: DEVICE: surgery utilizing V-Loc suture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study In Patients With Neuropathic Pain From Diabetic Peripheral Neuropathy (DPN)
Status: COMPLETED
Conditions: Neuropathy, Diabetic
Interventions: DRUG: Placebo|DRUG: GEn 1200mg/day|DRUG: GEn 2400mg/day|DRUG: GEn 3600mg/day|DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double Blind Study on the Gastrointestinal Effects of Arabinoxylan (Leaf Fiber Extract).
Status: UNKNOWN
Conditions: Gastrointestinal Tolerance
Interventions: DIETARY_SUPPLEMENT: 7.25 grams of Arabinoxylan leaf fiber extract|DIETARY_SUPPLEMENT: 14.5 grams of Arabinoxylan leaf fiber extract|DIETARY_SUPPLEMENT: Control - No Arabinoxylan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Usefulness of Medroxyprogesterone Acetate in Follicular Phase in Oocyte Donors. Undergoing Ovarian Stimulation
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Provera 10 mg.|DRUG: Ganirelix (GnRH antagonist)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SleepUp Digital CBTi-based Platform for Insomnia
Status: ACTIVE_NOT_RECRUITING
Conditions: Insomnia|Sleep Disorder|Sleep Hygiene
Interventions: BEHAVIORAL: Online Cognitive-Behavioral Therapy for Insomnia and complementary therapies|BEHAVIORAL: Regular Cognitive Behavioural Therapy for Insomnia|BEHAVIORAL: Sleep hygiene - minimal intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Investigate The Effect Of A Natural Dietary Supplement On Peri-Menopausal Symptoms
Status: TERMINATED
Conditions: Menopause
Interventions: DIETARY_SUPPLEMENT: proprietary formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Liposomal Bupivacaine for Acute Pain in Hip and Femur Fractures
Status: TERMINATED
Conditions: Femoral Fractures
Interventions: DRUG: Liposomal Bupivacaine|DRUG: Ropivacaine HCL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Yannianjiuzhuan Method and Reverse Breathing Training to Improve Constipation in Elderly Patients With Coronary Heart Disease
Status: COMPLETED
Conditions: Constipation|Coronary Heart Disease
Interventions: OTHER: Yannianjiuzhuan method combined with reverse breathing training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of NanoDoce Intratumoral Injection in Renal Cell Carcinoma
Status: WITHDRAWN
Conditions: Renal Cell Carcinoma|Kidney Cancer|Adenocarcinoma of Kidney|Adenocarcinoma, Renal|Renal Cell Cancer
Interventions: DRUG: NanoDoce (sterile nanoparticulate docetaxel) Powder for Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Cyanoacrylate Glue in the Fixation of Midline and Peripherally Inserted Central Catheters in Hospitalized Adult Patients: Randomised Clinical Trial (CIANO-ETI)
Status: COMPLETED
Conditions: Vascular Access Device|Catheterization, Peripheral|Nursing Care|Randomized Controlled Trial
Interventions: PROCEDURE: cyanoacrylate adhesive (SecurePortIV®)|PROCEDURE: standard cure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Palliative Care Educator
Status: COMPLETED
Conditions: Advance Care Planning|Palliative Care|Alzheimer's Disease and Related Dementias|Doctor-patient Communication|Video Decision Aids
Interventions: BEHAVIORAL: ACP Educator led, video assisted discussion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Reduction of AF Ablation Induced Thrombo-Embolic Incidence Pilot Study
Status: TERMINATED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: Cerebral Diffusion-Weighted Magnetic Resonance Imaging|DEVICE: Transesophageal Echocardiography|OTHER: Paperbased neurocognitive testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effect of High-fat/High-sugar Diet on Food Reward Signaling
Status: COMPLETED
Conditions: Behavior, Eating
Interventions: DIETARY_SUPPLEMENT: High-Fat/High-Sugar (HF/HS) Diet|DIETARY_SUPPLEMENT: Low-Fat/Low-Sugar (LF/LS) Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fracture Gap After Herbert Screw Insertion by 3d Stents Vs Titanium Plate(Minimally Displaced Mandibular Angle Fracture)
Status: UNKNOWN
Conditions: Minimally Displaced Mandibular Angle Fracture
Interventions: PROCEDURE: 3D stent in Herbert screw insertion vs titanium plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-PSMA PET and MRI in the Primary Staging of Prostate Cancer Patients
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: PSMA-1007 Positron Emission Tomography (PET) scan and 3T Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sensory Reeducation in Peripheral Nerve Injuries of Hand
Status: COMPLETED
Conditions: Median Nerve Disease|Ulnar Nerve Disease|Peripheral Nerve Disease
Interventions: OTHER: Training with a mirror|OTHER: No mirror therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Sacral Nerve Stimulation for Irritable Bowel Syndrome.
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DEVICE: Subsensory|DEVICE: OFF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sustain and Reinforce the Transition From Child to Adult Mental Health Care in Switzerland : A Monocentric Nested Cohort Randomized Controlled Trial: The SORT Study.
Status: UNKNOWN
Conditions: Psychiatric Disorder|Transition
Interventions: BEHAVIORAL: Managed transition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Effects Between Conventional Dose and High Dose Escitalopram on Clinical Improvement in Patients With Obsessive-compulsive Disorder
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: DRUG: escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Cluster Headache With TENS and ONS
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Cluster Headache|Primary Headache Disorder|Headache|Cluster Headache|Pain|Cephalgia|Trigeminal Autonomic Cephalgia
Interventions: DEVICE: Paresthesia-free (burst) ONS|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Breast Neoplasm|Breast Cancer Female|Breast Cancer Invasive|Breast Cancer Stage II|Breast Cancer Stage III|Triple Negative Breast Cancer|Hormone Receptor-positive Breast Cancer|HER2-positive Breast Cancer|Triple Negative Breast Neoplasms|Estrogen Receptor-positive Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Pembrolizumab|DRUG: Pertuzumab/Trastuzumab/Hyaluronidase-zzxf
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Gefapixant (AF-219/MK-7264) on Cough Reflex Sensitivity (MK-7264-015)
Status: COMPLETED
Conditions: Refractory Chronic Cough
Interventions: DRUG: Gefapixant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes in Shoulder Hemi-arthroplasty Using a PyC Spherical Interpositional Implant
Status: UNKNOWN
Conditions: Localized, Primary Osteoarthritis|Post-traumatic Arthrosis of Other Joints, Shoulder Region|Avascular Necrosis of the Head of Humerus
Interventions: DEVICE: Shoulder hemi-arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Riociguat on Bone Metabolism
Status: COMPLETED
Conditions: Pharmacology, Clinical
Interventions: DRUG: Riociguat (Adempas, BAY63-2521) immediate release tablet of 2.5 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Adrenal Suppression Potential and Pharmacokinetic Properties of CB-03-01 Cream in Subjects With Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: cortexolone 17α-propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PeriOcular and INTravitreal Corticosteroids for Uveitic Macular Edema Trial
Status: COMPLETED
Conditions: Macular Edema|Uveitis
Interventions: DRUG: Periocular triamcinolone 40 mg|DRUG: Intravitreal triamcinolone 4 mg|DRUG: Dexamethasone intravitreal implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Effection of Potassium Citrate Extended-release Tablets on Urolithiasis Formation or Recurrence
Status: UNKNOWN
Conditions: Urolithiasis
Interventions: DRUG: Potassium Citrate Extended-release Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Compare Pharmacokinetic Property of SYO-1644 Tab. and Nexavar Tab. in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy, Male
Interventions: DRUG: SYO-1644|DRUG: Nexavar tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of 18F-DCFPyL, a Second Generation Low-molecular Weight PSMA-based PET Radiotracer, in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: 18F-DCFPyL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trastuzumab Deruxtecan for the Treatment of HER2+ Newly Diagnosed or Recurrent Osteosarcoma
Status: SUSPENDED
Conditions: Osteosarcoma|Recurrent Osteosarcoma
Interventions: BIOLOGICAL: Trastuzumab Deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Dose-Escalation Study of INCB054329 in Patients With Advanced Malignancies
Status: TERMINATED
Conditions: Solid Tumors and Hematologic Malignancy
Interventions: DRUG: INCB054329 Monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety of Mavacamten in Korean Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy
Status: RECRUITING
Conditions: Obstructive Hypertrophic Cardiomyopathy
Interventions: DRUG: Mavacamten
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of IV Dexamethasone on the Duration of Analgesia of Spinal Anaesthesia for C-Sections at a Jamaican Hospital
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: Dexamethasone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DPP Feasibility Study of Breastfeeding - eMOMS 2.0
Status: RECRUITING
Conditions: Overweight or Obesity|Pregnancy
Interventions: BEHAVIORAL: Diabetes Prevention Program|BEHAVIORAL: Breastfeeding|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanical cervicAl ripeninG for Women With PrOlongedPregnancies
Status: COMPLETED
Conditions: Prolonged Pregnancy
Interventions: DEVICE: Mechanical cervical ripening|DRUG: Pharmacological cervical ripening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualizing Hemophilia Prophylaxis Using Thromboelastography
Status: COMPLETED
Conditions: Hemophilia A
Interventions: OTHER: Thromboelastography/Thromboelastometry-Guided Treatment Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Glycyrrhizin on the Occurrence of Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea
Interventions: DRUG: Ammonium Glycyrrhizinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of XGEVA® (Denosumab) in Chinese Adults and Skeletally Mature Adolescents With Giant Cell Tumor of the Bone
Status: RECRUITING
Conditions: Giant Cell Tumor of Bone
Interventions: DRUG: XGEVA®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Harmonic Scalpel Vs. Electrocautery in Breast Reduction Surgery
Status: TERMINATED
Conditions: Hyperplasia
Interventions: DEVICE: Harmonic Scalpel|DEVICE: Electrocautery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Optic Disc, Macula, and Retinal Nerve Fiber Layer Measurements Obtained by OCT in Thyroid Associated Ophthalmopathy
Status: COMPLETED
Conditions: Thyroid Associated Ophthalmopathy
Interventions: DEVICE: Optical Coherence Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Controlling Oral Malodor by ClōSYS® Oral Rinse
Status: COMPLETED
Conditions: Oral Malodor
Interventions: DRUG: ClōSYS® Unflavored Rinse|DRUG: ClōSYS® Flavored Rinse|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endometrial Effects of Metformin Action in Women With Polycystic Ovarian Syndrome (PCOS)
Status: COMPLETED
Conditions: Polycystic Ovarian Syndrome
Interventions: DRUG: Endometrin (progesterone 100mg vaginal inserts)|DRUG: Metformin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CO2 Rebreathing in nOH: A Proof-of-Concept Pilot Study
Status: RECRUITING
Conditions: Neurogenic Orthostatic Hypotension|Autonomic Failure
Interventions: DEVICE: CO2 ReHaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3437943 in Participants Who Have Obesity or Are Overweight
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DRUG: LY3437943|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of PENTABIOCEL in Clinical and Laboratory Recovery of Children With Celiac Disease
Status: COMPLETED
Conditions: Celiac Disease
Interventions: DIETARY_SUPPLEMENT: Pentabiocel|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Immuno-therapy Study of Experimental Medication BMS-986156, Given by Itself or in Combination With Nivolumab in Patients With Solid Cancers or Cancers That Have Spread.
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: BMS-986156|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery With or Without Hepatic Arterial Chemotherapy in Treating Patients With Liver Cancer
Status: WITHDRAWN
Conditions: Localized Resectable Adult Primary Liver Cancer|Stage III Childhood Liver Cancer
Interventions: DRUG: cisplatin|DRUG: fluorouracil|PROCEDURE: adjuvant therapy|PROCEDURE: chemotherapy|PROCEDURE: conventional surgery|PROCEDURE: hepatic arterial infusion|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of a Traditional Dietary Intervention on Diabetes Mellitus and Cardiovascular Disease Risk Factors in a First Nation Community: A Pilot Study
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Cardiovascular Disease|Obesity
Interventions: BEHAVIORAL: Dietary Intervention (Macronutrient composition)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Eye Movement Desensitization and Reprocessing (EMDR) in Dental Phobia
Status: COMPLETED
Conditions: Dental Phobia
Interventions: BEHAVIORAL: Eye Movement Desensitization and Reprocessing (EMDR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Ultrasound (EUS)-Guided Ablation of Pancreatic Cysts
Status: COMPLETED
Conditions: Pancreatic Cyst|Pancreatic Intraductal Papillary-Mucinous Neoplasm|Cystadenoma, Mucinous|Papillary Mucinous Cystadenoma, Borderline Malignancy
Interventions: PROCEDURE: 98% Ethanol & Paclitaxel injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of Single Escalating Doses of BI 1034020 Administered Intravenously or Subcutaneously to Male Healthy Volunteers
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: BI 1034020|DRUG: Placebo to BI 1034020
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Evaluating Chlorine e6 Derivative-mediated Antimicrobial Photodynamic Therapy as a Treatment for Denture Stomatitis
Status: COMPLETED
Conditions: Health Care Associated Infection
Interventions: DRUG: Nystatin|PROCEDURE: Antimicrobial Photodynamic Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate OBI-833/OBI-821 in Combination With First-Line Erlotinib in Patients With EGFR-Mutated, Globo H-Positive, Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: 30 μg OBI-833/100 μg OBI-821|DRUG: Erlotinib (150 mg daily)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Acetazolamide for Obstructive Sleep Apnea to Improve Heart Health
Status: RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Acetazolamide|DRUG: Placebo|DEVICE: Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of a Novel Device for Stretch Relaxation During Mohs Surgery
Status: UNKNOWN
Conditions: Tissue Expander Disorder|Stress Strain Curve|Tissue Expansion|Mohs Surgery
Interventions: DEVICE: Peak Force Measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: BAX 855 PK-guided Dosing
Status: COMPLETED
Conditions: Hemophilia A
Interventions: BIOLOGICAL: PEGylated Recombinant Factor VIII|BIOLOGICAL: PEGylated Recombinant Factor VIII|BIOLOGICAL: PEGylated Recombinant Factor VIII
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Induction of Donor Specific Tolerance in Recipients of Live Donor Kidney Allografts by Donor Stem Cell Infusion
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Failure
Interventions: BIOLOGICAL: Enriched Hematopoietic Stem Cell Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SOLITAIRE™ FR With the Intention For Thrombectomy (SWIFT) Study
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DEVICE: SOLITAIRE™ Device|DEVICE: MERCI® Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prostate Cancer Intensive, Non-Cross Reactive Therapy (PRINT) for Castration Resistant Prostate Cancer (CRPC)
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Abiraterone acetate|DRUG: Prednisone|DRUG: Radium-223 dichloride|DRUG: cabazitaxel|DRUG: Carboplatin|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of 1 Hour Clear Fluid Fasting Prior to Paediatric GA
Status: COMPLETED
Conditions: Gastric Residual Volume
Interventions: OTHER: Fasting time for clear fluid prior to anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Melphalan, Fludarabine, and Alemtuzumab Followed by Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: BIOLOGICAL: alemtuzumab|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: melphalan|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Catheter Related Bladder Discomfort (CRBD) With Bilateral Pudendal Nerve Block
Status: UNKNOWN
Conditions: Bladder Neoplasm|Prostatic Neoplasms
Interventions: DRUG: pudendal nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Resistant Starch Type 4 on Glycemia and Insulin Sensitivity in Young Adults
Status: COMPLETED
Conditions: Hyperglycemia
Interventions: DIETARY_SUPPLEMENT: Resistant starch type 4 - raw|DIETARY_SUPPLEMENT: Resistant Starch Type 4 - Cooked|DIETARY_SUPPLEMENT: Dextrose|DIETARY_SUPPLEMENT: Puffed Wheat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MeFirst: A Tailored Intervention to HPV Vaccine Decision Making
Status: COMPLETED
Conditions: Human Papillomavirus-Related Carcinoma
Interventions: BEHAVIORAL: MeFirst Tailored Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dasatinib Plus Radiation Therapy/Temozolomide in Newly-Diagnosed Glioblastoma
Status: TERMINATED
Conditions: Glioblastoma|CNS Disease|Brain Diseases
Interventions: DRUG: Dasatinib|RADIATION: RT (Radiotherapy)|DRUG: TMZ (Temozolomide)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incidence of Renal Tubular Acidosis in Nephrology Unit in Assiut University Childern Hospital
Status: UNKNOWN
Conditions: Renal Tubule Acidosis
Interventions: DIAGNOSTIC_TEST: Arterial blood gases|DIAGNOSTIC_TEST: Blood anion gap|DIAGNOSTIC_TEST: serum electrolytes|DIAGNOSTIC_TEST: renal function test|DIAGNOSTIC_TEST: urine analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pembrolizumab and Sunitinib Malate in Treating Participants With Refractory Metastatic or Unresectable Thymic Cancer
Status: SUSPENDED
Conditions: Thymic Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab|DRUG: Sunitinib Malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Delineating Between Pathophysiologic Phenotypes of Hypoxic Ischemic Brain Injury After Cardiac Arrest
Status: RECRUITING
Conditions: Hypoxia-Ischemia, Brain
Interventions: DEVICE: Neuromonitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Aripiprazole in the Treatment of Patients With Psychosis Associated With Dementia of Alzheimer's Type
Status: COMPLETED
Conditions: Dementia, Alzheimer Type
Interventions: DRUG: Aripiprazole (BMS-337039)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Healthy Moms, Healthy Babies
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Gestational Diabetes
Interventions: DEVICE: Continuous Glucose Monitoring|DEVICE: Glucose Meter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of BiRd Regimen Combined With BCMA CAR T-cell Therapy in Newly Diagnosed Multiple Myeloma (MM) Patients
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: clarithromycin, lenalidomide, dexamethasone and autologous BCMA-directed CAR T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eosinophil-driven Corticotherapy for Patients Hospitalized for COPD Exacerbation
Status: RECRUITING
Conditions: COPD Exacerbation
Interventions: DRUG: 5 days of systemic corticotherapy (prednisone)|DRUG: 5 days of placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PEG-somatropin Injection to Treat Children of Turner Syndrome
Status: UNKNOWN
Conditions: Turner Syndrome
Interventions: BIOLOGICAL: PEG-rhGH low dose|BIOLOGICAL: PEG-rhGH high dose|OTHER: Non-treatment control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study to Evaluate an Occlusion Based Dentifrice in Relief of Dentinal Hypersensitivity
Status: COMPLETED
Conditions: Dentine Hypersensitivity
Interventions: DRUG: 5% calcium sodium phosphosilicate/ sodium monofluorophosphate dentifrice|DRUG: 0% calcium sodium phosphosilicate/sodium monofluorophosphate dentifrice|DRUG: Sodium monofluorophosphate dentifrice|DRUG: Sodium fluoride dentifrice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT