pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Web-based International Register of Emergency Surgery and Trauma
Status: RECRUITING
Conditions: Acute Appendicitis|Acute Cholecystitis|Acute Diverticulitis|Post-operative Complications|Acute Pancreatitis|Perforated Gastro-duodenal Ulcers|Adhesive Small Bowell Occlusion|Colonic Neoplastic Emergencies|Gynecological Emergencies|Vascular Emergencies|Intestinal Ischemia|Abdominal Wall Hernia|Foreign Bodies|Caustic Ingestion|Trauma
Interventions: PROCEDURE: Emergency General Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Calcipotriol Plus Betamethasone Dipropionate Gel in Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Calcipotriol plus betamethasone dipropionate (LEO 80185) gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Intervention Study of Dietary Intake on Energy Expenditure
Status: COMPLETED
Conditions: Healthy and Overweight/ Obesity Males
Interventions: DIETARY_SUPPLEMENT: 1. Low-fat and high-carbohydrate diet; 2. High-fat and low-carbohydrate diet; 3. High-protein and low-fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Head Repositioning Accuracy During Experimental Neck Pain
Status: COMPLETED
Conditions: Healthy|Neck Pain
Interventions: DRUG: Injection of hypertonic saline|DRUG: Injection of Isotonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Probiotic on Psychological and Cognitive Effects
Status: COMPLETED
Conditions: Aging
Interventions: DIETARY_SUPPLEMENT: Probiotic - Lactobacillus Rhamnosus GG|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Healthy Volunteer Study To Assess The Bioavailability of GSK1265744 When Administered Orally Either When Fasted or Following a Meal.
Status: COMPLETED
Conditions: HIV Infection|Infection, Human Immunodeficiency Virus
Interventions: DRUG: GSK1265744 10 mg oral solution|DRUG: GSK1265744 5 mg tablet|DRUG: GSK1265744 5 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Negative Pressure Wound Therapy Use to Decrease Surgical Nosocomial Events in Colorectal Resections
Status: COMPLETED
Conditions: Postoperative Surgical Site Infections
Interventions: DEVICE: Negative Pressure Wound Therapy|OTHER: Usual Care of Surgical Wound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Incentives for Daily Tooth Brushing to Reduce Gingivitis
Status: COMPLETED
Conditions: Gingivitis
Interventions: BEHAVIORAL: Financial Incentives|BEHAVIORAL: Cognitive Incentives|BEHAVIORAL: Financial and Cognitive Incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Treatment of Periodontitis in Menopausal Patients
Status: COMPLETED
Conditions: Menopausal Patients|Chronic Periodontitis|Omega 3 Fatty Acids
Interventions: DRUG: Polyunsaturated Fatty Acids|DIETARY_SUPPLEMENT: olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: B-type Natriuretic Peptide as a Surrogate Marker Guiding Post-operative Fluid Off-loading
Status: COMPLETED
Conditions: Fluid Over-load
Interventions: DRUG: Furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Objective of This Multicentre Study is to Collect Operative Data on the Related Clinical Functional Outcomes and Complications and of Market Approved Alcis Electrophysiology Catheters to Demonstrate Safety and Performance of These Devices in a Real-world Setting
Status: COMPLETED
Conditions: Cardiac Arrhythmia
Interventions: DEVICE: Electrophysiology catheters and cables
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reduction of Concussion Symptoms Through the Use of Osteopathic Manipulative Therapy
Status: TERMINATED
Conditions: Concussion, Brain
Interventions: PROCEDURE: Osteopathic Manipulative Therapy|PROCEDURE: Standard of Care Concussion Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesalazine for the Treatment of Diarrhoea-predominant Irritable Bowel Syndrome (IBS-D)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Diarrhoea
Interventions: DRUG: Mesalazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Translational Research Examining Acupuncture Treatment in Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DEVICE: Acupuncture|DEVICE: Sham Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Potassium Level in Venous Blood Samples Drawn and Heel Sticks In Infants and Newborns
Status: COMPLETED
Conditions: Hyperkalemia
Interventions: OTHER: Blood sample drawn from a vein|OTHER: Blood sample drawn from a heel stick
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: FIH Phase I/IIa Trial Evaluating Safety of TUM012 to Minimize Ischemic Reperfusion Injury in Kidney Transplantation
Status: COMPLETED
Conditions: Ischemia-reperfusion Injury|Kidney Transplant; Complications
Interventions: DRUG: TUM012|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effects of Phlebotomy on Insulin Sensitivity in Insulin Resistance-associated Hepatic Iron Overload Patients
Status: COMPLETED
Conditions: Insulin Resistance|Iron Overload
Interventions: PROCEDURE: phlebotomy|BEHAVIORAL: dietary and lifestyle counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ethinyl Estradiol and Cyproterone Acetate in Irregular Menstruation
Status: UNKNOWN
Conditions: Amenorrhea|Dysmenorrhea|Menstruation Disturbances|Hyperandrogenism
Interventions: DRUG: Ethinyl Estradiol + Cyproterone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy of Hypertonic Saline vs Adrenaline Nebulization in Acute Bronchiolitis
Status: RECRUITING
Conditions: Acute Bronchiolitis Due to Respiratory Syncytial Virus
Interventions: DRUG: Hypertonic Saline Solution, 1 Ml|DRUG: Adrenaline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Low-Fat And Low-Cholesterol Dietary Intervention On LDL Sub-Groups In Turkısh Dyslipidemic Patients
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: BEHAVIORAL: Low-fat and low-cholesterol diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cinnamon Extract on Menstrual Cycles in PolyCystic Ovary Syndrome (PCOS)
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Cinnamon Extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Different Toric Intraocular Lenses on IOL-capsular Complex
Status: UNKNOWN
Conditions: Corneal Astigmatism|Cataract
Interventions: PROCEDURE: Cataract surgery with AcrySof IQ IOL implantation.|PROCEDURE: Cataract surgery with TECNIS toric IOL implantation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Varenicline and Bupropion for Smoking Cessation
Status: COMPLETED
Conditions: Smoking
Interventions: DRUG: Varenicline|DRUG: placebo|DRUG: bupropion SR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Laparoscopic Traditional and Knotless Sutures
Status: COMPLETED
Conditions: Anastomosis, Roux-en-Y|Surgical Operation With Anastomosis, Bypass or Graft
Interventions: DEVICE: Stratafix|DEVICE: Vicryl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of the Effect of Dose-Titration of Prucalopride for The Treatment of Chronic Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Prucalopride|DRUG: Prucalopride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Correcting Residual Errors With Spectral, Ultrasound, Traditional Speech Therapy
Status: RECRUITING
Conditions: Speech Sound Disorder
Interventions: BEHAVIORAL: Biofeedback-ultrasound|BEHAVIORAL: Biofeedback--visual-acoustic|BEHAVIORAL: Traditional articulation treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SPIRIT 1: Efficacy and Safety Study of Relugolix in Women With Endometriosis-Associated Pain
Status: COMPLETED
Conditions: Endometriosis Related Pain
Interventions: DRUG: Relugolix|DRUG: Estradiol/norethindrone acetate|DRUG: Estradiol/norethindrone acetate placebo|DRUG: Relugolix placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Acute Alcohol Intoxication on Neural Processes During Decisions to Engage in HIV Risk Behaviors
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: OTHER: Alcohol beverage|OTHER: Placebo beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Thromboaspiration in Patients With High Thrombotic Burden Undergoing Primary Percutaneous Coronary Intervention (PCI)
Status: COMPLETED
Conditions: Primary PCI for STEMI
Interventions: DEVICE: coronary thrombectomy|DEVICE: standard primary PCI (with stenting, as required)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enabling Symptom Identification and Tracking in Children Receiving Cancer Treatment
Status: COMPLETED
Conditions: Pediatric Cancer|Quality of Life|Symptom Screening
Interventions: OTHER: Symptom feedback to Health Care Provider|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study
Status: RECRUITING
Conditions: Tumors Metastatic to Brain
Interventions: RADIATION: radiosurgery|PROCEDURE: therapeutic conventional surgery|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Second Curettage in Treating Patients With Persistent Non-metastatic Gestational Trophoblastic Tumors
Status: COMPLETED
Conditions: Complete Hydatidiform Mole|Non-Metastatic Gestational Trophoblastic Tumor|Partial Hydatidiform Mole
Interventions: OTHER: Laboratory Biomarker Analysis|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anterior Lingual Frenectomy is Inadequate in Improving Breastfeeding Outcomes: a Prospective Cohort Study
Status: COMPLETED
Conditions: Ankyloglossia|Breastfeeding
Interventions: PROCEDURE: Lingual frenotomy and/or maxillary labial frenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetics of Women With Lobular Carcinoma in Situ of the Breast
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: GENETIC: gene expression analysis|GENETIC: molecular diagnostic method|GENETIC: polymorphism analysis|GENETIC: protein expression analysis|OTHER: medical chart review|OTHER: questionnaire administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CHAMPS Study: Chronic HepAtitis C Management to ImProve OutcomeS
Status: COMPLETED
Conditions: Hepatitis C Virus Infection, Response to Therapy of|Human Immunodeficiency Virus
Interventions: OTHER: Usual care plus peer-mentors|OTHER: Usual care plus incentives|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Acceptability Study of Oral Emtricitabine/Tenofovir Disoproxil Fumarate Tablet and Rectally-Applied Tenofovir Reduced-Glycerin 1% Gel
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Oral FTC/TDF (Daily Emtricitabine/Tenofovir Disoproxil fumarate Tablet)|DRUG: Rectal Daily TFV RG 1% gel (Rectally applied Tenofovir Reduced Glycerin 1% Gel)|DRUG: Rectal RAI-associated TFV RG 1% gel (Receptive Anal Intercourse Associated rectally applied Tenofovir Reduced Glycerin 1% Gel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Changes of Cognitive Function and Brain Magnetic Resonance in Maintenance Hemodialysis Patients With Diabetes Mellitus
Status: RECRUITING
Conditions: Maintenance Hemodialysis
Interventions: DIAGNOSTIC_TEST: Chinese version of the Montreal Cognitive Assessment Scale (MoCA) and brain magnetic resonance high resolution structural imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Zanubrutinib in Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Status: COMPLETED
Conditions: Relapsed or Refractory Chronic Lymphocytic Leukemia|Relapsed or Refractory Small Lymphocytic Lymphoma
Interventions: DRUG: Zanubrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid-Free Combined Anesthesia With Spontaneous Breathing for VATS
Status: NOT_YET_RECRUITING
Conditions: Video-assisted Thoracoscopic Lung Surgery；Anesthesia
Interventions: DRUG: opioid based strategy|DRUG: opioid-free strategy|PROCEDURE: Laryngeal mask airway; Preserved spontaneous breathing|PROCEDURE: Double lumen tracheal tube; Mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Inspiratory Muscle Training and Neuromuscular Electrical Stimulation in Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Multimodal training|DEVICE: IMT + Pulmonary Rehabilitation|DEVICE: NMES + Pulmonary Rehabilitation|DEVICE: Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Combination of Panobinostat and Carfilzomib in Patients With Relapsed/Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: panobinostat|DRUG: carfilzomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Closing the Gap on Postoperative Seroma and Recurrences in Laparoscopic Ventral Hernia Repair
Status: COMPLETED
Conditions: Ventral Hernia
Interventions: PROCEDURE: Closure of hernia defect.|PROCEDURE: No closure of the hernia defect.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Different Paediatric Rotary Files and Manual K-file in Root Canal Treatment of Primary Teeth
Status: UNKNOWN
Conditions: Root Canal Treatment
Interventions: DEVICE: Pediatric Rotary File Systems
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Discomfort and Ocular Redness Following Phacoemulsification Surgery
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Systane Ultra|DRUG: tobradex quid (Standard)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Daily Four Times or Two Times Usage of PPI and Amoxicillin for the First or Second Line H. Pylori Eradication
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection|Helicobacter Gastritis|Helicobacter-Associated Pyloric Ulcer
Interventions: DRUG: Rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chidamide Plus Camrelizumab as Second-line Therapy for Advanced ESCC Treated With PD-1 Blockade
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: chidamide + camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Chronic Use of Doxazosin in Men With Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Doxazosin|DRUG: Doxazosin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of an Infrared Visualization Technique for the Identification of the Peripheral Venous Access Site in Patients With Cystic Fibrosis Aged 12 Years and Older
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DEVICE: Vein Illumintion System device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Exercise and Improved Nitric Oxide Bioavailability on Arteriovenous Fistula Maturation
Status: TERMINATED
Conditions: End Stage Renal Disease
Interventions: OTHER: Handgrip training|DRUG: Nitroglycerin ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy Trial of Oral Tetrahydrocannabinol in Patients With Fibromyalgia
Status: UNKNOWN
Conditions: Fibromyalgia
Interventions: DRUG: Tetrahydrocannabinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Bortezomib (Velcade) in Combination With Dexamethasone to Treat Patients With Relapsed Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Hodgkin Disease
Interventions: DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare the Efficacy of Rosuvastatin to Atorvastatin in High Risk Patients With Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Rosuvastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Surgical Guide Assisted Dental Implantation in Bangladesh
Status: RECRUITING
Conditions: Partially Edentulous Mandible|Dental Implantation
Interventions: DEVICE: Surgical Guide|PROCEDURE: Guide-pin-assisted Freehand surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Study on the Efficacy and Safety of Enteric-coated Mycophenolate Sodium Administered in de Novo Kidney Transplant Patients
Status: COMPLETED
Conditions: De Novo Kidney Transplantation
Interventions: DRUG: Enteric-Coated Mycophenolate Sodium (EC-MPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating Neratinib Plus Paclitaxel VS Trastuzumab Plus Paclitaxel In ErbB-2 Positive Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Neratinib|DRUG: Trastuzumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Trial of MLN8237 in Adult Participants With Acute Myelogenous Leukemia and High-Grade Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|High-Grade Myelodysplastic Syndrome
Interventions: DRUG: Alisertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motivation of Nursing Students and Perception Levels of the Taboo Game Adapted for Nursing Diagnoses
Status: NOT_YET_RECRUITING
Conditions: Nursing Diagnosis|Taboo Game|Motivation
Interventions: OTHER: nursing diagnoses - taboo game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of the InsuPatch on Automated Closed-loop Glucose Control in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: ePID closed loop system|DEVICE: InsuPatch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Interscalene Nerve Block on Cerebral Perfusion During Surgery in the Beachchair Position
Status: COMPLETED
Conditions: Cerebral Ischemia
Interventions: PROCEDURE: Interscalene nerve block and catheter|PROCEDURE: Interscalene catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Ranolazine on Arrhythmias and Microvolt T- Wave Alternans (MVTWA) Patients With LV Dysfunction
Status: COMPLETED
Conditions: Sudden Cardiac Death|Ventricular Arrythmias
Interventions: DRUG: Ranolazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NMES to Improve Eyelid Functions in Cranial Nerve (CN) III and VII Palsy
Status: TERMINATED
Conditions: Blepharoptosis|Lagophthalmos
Interventions: DEVICE: Neuromuscular electrical stimulation|DEVICE: Sham neuromuscular electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of SP2086 in Combination With Metformin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Placebo /Metformin|DRUG: SP2086(50 mg q.d.)/Metformin|DRUG: SP2086 (100 mg q.d.)/Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Accuracy Evaluation of EarlySense With Modified Sensor (Smaller Shape Sensor With BLE) at Home Setting Monitoring a Subject While Partner in Bed
Status: UNKNOWN
Conditions: Sleep Disorder
Interventions: DEVICE: EarlySense Noomi system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Influence of Lifestyle Factors on Neutrophil Migration Pilot Study
Status: COMPLETED
Conditions: Neutrophil Chemotactic Response
Interventions: BEHAVIORAL: Exercise|DRUG: ProLab 200mg caffeine capsule|OTHER: Ethanol ingestion|DRUG: Glucose Tolerance Drink
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Pharmacokinetics of Two Vaginal Film Formulations Containing the Integrase Inhibitor MK-2048
Status: COMPLETED
Conditions: Pharmacokinetics|Safety
Interventions: COMBINATION_PRODUCT: MK-2048 High Eudragit Vaginal Film|COMBINATION_PRODUCT: MK-2048 Low Eudragit Vaginal Film
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Trial of 2 Antibody Induction Steroid Avoidance Protocols
Status: COMPLETED
Conditions: Transplant; Failure, Kidney
Interventions: DRUG: Alemtuzumab|DRUG: Daclizumab|DRUG: Thymoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparative Study of Dorzotimol Eye Drops, 20 mg/mL + 5 mg/mL Versus Cosopt® Eye Drops, 20 mg/mL + 5 mg/mL
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma of Both Eyes
Interventions: DRUG: Dorzotimol eye drops, 20 mg/mL + 5 mg/mL|DRUG: Cosopt eye drops, 20 mg/mL + 5 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency-Guided Localization in Patients With Abnormal Breast Tissue Undergoing Lumpectomy
Status: WITHDRAWN
Conditions: Breast Neoplasm
Interventions: PROCEDURE: Lumpectomy|OTHER: Questionnaire Administration|PROCEDURE: Radiofrequency-Guided Localization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ultraprotective Ventilation Without Extracorporeal Circulation During COVID 19 Pneumonia
Status: UNKNOWN
Conditions: Acute Respiratory Distress Syndrome|COVID19|Sars-CoV2|Pneumonia
Interventions: OTHER: PROTECTIVE VENTILATION|OTHER: ULTRAPROTECTIVE VENTILATION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of NGM438 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer|Breast Cancer|Gastric Cancer|Non Small Cell Lung Cancer|Cervical Cancer|Endocervical Cancer|Squamous Cell Carcinoma of Head and Neck|Bladder Urothelial Cancer|Colorectal Cancer|Esophageal Cancer|Ovarian Cancer|Renal Cell Carcinoma|Prostate Cancer|Melanoma|Mesothelioma|Cholangiocarcinoma
Interventions: DRUG: NGM438|DRUG: Pembrolizumab (KEYTRUDA ®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cuff Pressure Regulation Apparatus for Tracheal Intubation in Children
Status: COMPLETED
Conditions: Cuff Overinflation|Cuff Underinflation
Interventions: DEVICE: Electronic device (VBM©)|DEVICE: Pneumatic device (Nosten©)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing Two Methods of Contractions Monitoring for Clinical Decision Making Regarding Treatment Among Pregnant Women With Preterm Contractions.
Status: UNKNOWN
Conditions: Fetal Heartbeat Tracings
Interventions: DEVICE: EUM|DEVICE: Tocodynamometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Topical Preparation of Pomegranate and Ginkgo Biloba for Anti-aging Activities
Status: UNKNOWN
Conditions: Skin and Subcutaneous Tissue Disorders
Interventions: DRUG: Cream Base|DRUG: Pomegrante and Ginkgo biloba group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Domperidone for the Treatment of Chronic Nausea and Vomiting Secondary to Gastroparesis
Status: COMPLETED
Conditions: Patients With Gastroparesis Who Have Failed Standard Therapy
Interventions: DRUG: Domperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of Exenatide on Brain Glucose Metabolism
Status: COMPLETED
Conditions: Impaired Glucose Tolerance (IGT)|Diabetes
Interventions: DRUG: Exenatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigation of Pharmacodynamic Characteristics of Explorative Formulation of Insulin Degludec in Male Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Activity To Improve Outcomes in Peripheral Arterial Disease
Status: COMPLETED
Conditions: Peripheral Arterial Occlusive Disease
Interventions: OTHER: Active Exercise|OTHER: Neuromuscular electrical stimulation|OTHER: Weight loss and active exercise|OTHER: Ad lib activity at home
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SC0245 and Irinotecan in Treating Patients With Relapsed Extensive-Stage Small Cell Lung Cancer (ES-SCLC)
Status: RECRUITING
Conditions: Small Cell Lung Cancer
Interventions: DRUG: SC0245|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mogamulizumab + Low-Dose Total Skin Electron Beam Tx in Mycosis Fungoides & Sézary Syndrome
Status: RECRUITING
Conditions: Sezary Syndrome|Mycosis Fungoides
Interventions: DRUG: Mogamulizumab|RADIATION: LD TSEBT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Per Oral Endoscopic Myotomy (POEM) for Esophagogastric Junction Outflow Obstruction (EGOO)
Status: COMPLETED
Conditions: Esophagogastric Junction Outflow Obstruction
Interventions: PROCEDURE: POEM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tadalafil Administration on Vasodilatation Mediated by Flow in Patients With Obesity Grade I-II
Status: UNKNOWN
Conditions: Obesity and Erectile Dysfuntion
Interventions: DRUG: Tadalafil 20 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Echinacea Angustifolia (AnxioCalm) in Anxiety
Status: TERMINATED
Conditions: Generalized Anxiety Disorder
Interventions: DIETARY_SUPPLEMENT: Echinacea angustifolia|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Compassion Project: Developing an Empathy-Based Stress Intervention
Status: NOT_YET_RECRUITING
Conditions: Reduction of Empathy-Based Stress in Healthcare Staff
Interventions: OTHER: The Compassion Project: Intervention to Reduce Empathy-Based Stress in Staff
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In-hospital Clinical Outcome of Deferred Stenting Versus Immediate Stenting in the Management of Acute STEMI Presenting With High Thrombus Burden.
Status: NOT_YET_RECRUITING
Conditions: Coronary Thrombosis
Interventions: PROCEDURE: Primary Percutaneous coronary angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Financial Incentives to Translate ALLHAT Into Practice: A Randomized Trial
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Physician-level financial incentives|BEHAVIORAL: Practice-level financial incentives|BEHAVIORAL: Physician- and practice-level financial incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency
Status: COMPLETED
Conditions: Severe Combined Immunodeficiency Syndrome
Interventions: DRUG: CD34+ cells transduced with ADA retrovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Chemotherapy-Free pCR-Guided Strategy With Trastuzumab-pertuzumab and T-DM1 in HER2-positive Early Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Early Breast Cancer
Interventions: DRUG: Trastuzumab and Pertuzumab (FDC SC) and T-DM1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Expression and Functions of the KIR3DL2 Receptor and the Anti-inflammatory Activity of IPH4102 in Blood Samples
Status: COMPLETED
Conditions: Axial Spondyloarthritis (axSpA)|Ankylosing Spondylitis (AS)
Interventions: BIOLOGICAL: blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ketamine for Endoscopic Sedation in Outpatient Adult Endoscopy.
Status: COMPLETED
Conditions: Administration and Dosage of Ketamine|Endoscopic Sedation
Interventions: DRUG: Ketamine|DRUG: Midazolam injection|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MDR - Biomet Cannulated Screws
Status: ENROLLING_BY_INVITATION
Conditions: Fractures, Bone|Fracture Multiple
Interventions: DEVICE: Biomet Cannulated Screw: 3.0, 4.0, 5.0, 6.5, and 8.0mm screws.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Flexiquit+: Web Program to Promote Smoking Cessation in Sexual and Gender Minority Young Adult Smokers
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: BEHAVIORAL: Computer-Assisted Smoking Cessation Intervention|OTHER: Text Message|OTHER: Handout|OTHER: Questionnaire Administration|OTHER: Quality-of-Life Assessment|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase I/II Study of EP-guided Noninvasive Cardiac Radioablation for Treatment of Ventricular Tachycardia
Status: COMPLETED
Conditions: Ventricular Tachycardia|Cardiomyopathy|Premature Ventricular Contractions
Interventions: RADIATION: stereotactic body radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Serum Myokine Dosages and Imaging Methods in the Evaluation of Sarcopenia in Patients With Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Sarcopenia|Hepatocellular Carcinoma
Interventions: OTHER: Dynamometry measurement, myokine dosing, sarcopenia calculation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Testing Counseling Styles to Motivate Smokers to Quit
Status: COMPLETED
Conditions: Smoking|Tobacco Use|Nicotine Dependence
Interventions: BEHAVIORAL: Brief Advice (BA)|BEHAVIORAL: Motivational Interviewing (MI)|BEHAVIORAL: Health Education (HE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Adjunctive Granisetron Therapy in Patients With Sepsis or Septic Shock
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: Granisetron Hydrochloride|DRUG: Placebo（Normal saline）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Treatment of Massive Rotator Cuff Tears With Debridement and Biodegradable Spacer.
Status: RECRUITING
Conditions: Massive Rotator Cuff Tears
Interventions: PROCEDURE: Biodegradable spacer|PROCEDURE: Debridement and biceps tenotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Desflurane on Myocardial Function in Patients Undergoing Coronary Artery Bypass Grafting
Status: UNKNOWN
Conditions: Coronary Artery Bypass Graft Redo|General Anesthetic Drug Adverse Reaction
Interventions: DRUG: Desflurane|DRUG: propofol|DRUG: sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Different Protocols of Fluid Therapy in Severe Preeclamptic Patients Under Spinal Anesthesia
Status: UNKNOWN
Conditions: Hypotension Drug-Induced
Interventions: DRUG: Lactated Ringer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cetuximab and Dasatinib in Recurrent Squamous Cell Carcinoma
Status: TERMINATED
Conditions: Squamous Cell Carcinoma Of The Head And Neck
Interventions: DRUG: Cetuximab|DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enema Use and Acceptability in HIV Negative Men Who Have Sex With Men
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Fleet Enema|DRUG: tap water enema|DRUG: Normosol-R enema
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of TNX-650 to Treat Refractory Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Hodgkin's Lymphoma
Interventions: DRUG: TNX-650
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A PhaseⅡ of Injection for Recombinant Human Tissue Plasminogen Kinase Derivative in Treatment of Acute Ischemic Stroke.
Status: UNKNOWN
Conditions: Acute Ischemic Stroke
Interventions: DRUG: r-PA|DRUG: r-PA|DRUG: Alteplase for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Assess Safety, Efficacy and In-use Tolerability of Different Dosages of Hair Growth Products in Patients With Mild to Moderate Androgenic Alopecia (Grade I to III).
Status: NOT_YET_RECRUITING
Conditions: Androgenic Alopecia
Interventions: OTHER: SesZen-Bio Low Dose 1 (350 mg extract)|OTHER: SesZen-Bio Low Dose 1 (150 mg liposomal)|OTHER: SesZen-Bio High Dose 1 (500 mg extract)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Efficacy of Inquiry Based Stress Reduction (IBSR) for Depression, a Clinical Trial
Status: UNKNOWN
Conditions: Depression
Interventions: BEHAVIORAL: Inquiry Based Stress Reduction (IBSR)|BEHAVIORAL: Cognitive Behavioral Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Randomized, Open, Phase III Trial of ddEC-THPvs Evaluating the Efficacy and Safety of TCHP Neoadjuvant Therapy for HER2-positive Breast Cancer
Status: RECRUITING
Conditions: HER-2 Positive Breast Cancer
Interventions: DRUG: TCbHP VS ddEC-THP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brexpiprazole as Adjunctive Therapy With Major Depressive Disorder and an Inadequate Response to Previous Adjunctive Therapy
Status: COMPLETED
Conditions: Major Depressive Disorder (MDD)
Interventions: DRUG: ADT|DRUG: Brexpiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRE-ProstAtectomy MRI-GuidEd Stereotactic Body RadioTherapy for High-Risk Prostate Cancer Trial (PREPARE SBRT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Dose escalation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrated Community Case Management (ICCM) Delivered by Village Health Teams in Bushenyi District in Uganda
Status: COMPLETED
Conditions: Maternal and Child Health
Interventions: OTHER: ICCM delivered by VHT|OTHER: ICCM delivered by VHT with Cell Phone|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Post-operative Analgesia of the Virtual Reality Using a Mirror Therapy After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Nociceptive Pain|Virtual Reality
Interventions: DEVICE: Mirrored Virtual reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of New-onset Diabetes After Transplantation Between Two Steroid Withdrawal Group With CellCept
Status: UNKNOWN
Conditions: Diabetes
Interventions: DRUG: Mycophenolate mofetil, Corticosteroids|DRUG: Corticosteroids, Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Selected Physical Therapy Exercise Program and Transcutaneous Electrical Nerve Stimulation on Patients With Pudendal Neuralgia
Status: COMPLETED
Conditions: Pudendal Neuralgia
Interventions: OTHER: Exercise therapy program plus TENS therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hepato-renal Regulation of Water Conservation in Heart Failure Patients With SGLT-2 Inhibitor Treatment
Status: COMPLETED
Conditions: Diabetes Mellitus|Heart Failure
Interventions: DRUG: Dapagliflozin 10 MG [Forxiga]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Cognitive Behavioral Therapy and Virtual Reality Use in Inured Athletes
Status: RECRUITING
Conditions: Re-injury Anxiety|Kinesiophobia|Poor Rehabilitation Adherence|Poor Rehabilitation Self Efficacy
Interventions: BEHAVIORAL: CBT+VR (Cognitive behavioral therapy and virtual reality)|BEHAVIORAL: VR (Virtual reality)|BEHAVIORAL: CBT (Cognitive behavioral therapy)|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Cutoff Point for Caval Index and Its Correlation With Central Venous Pressure and Plasma Lactate Level for Assessing Patients in Hypovolemic Hemorrhagic States
Status: COMPLETED
Conditions: IVC Collapsibility Index|Hemorrhagic Shock
Interventions: OTHER: Measuring IVC collapsibility index by bedside ultrasonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Immunogenicity Study of Human Papilloma Virus Vaccine in Women Aged 9 to 30 and Men Aged 9 to 17
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: BIOLOGICAL: Tetravalent recombinant human papilloma virus vaccine (6,11,16,18 type) (Hansenula polymorpha)|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: New Technologies for Endoscopic Treatment of Bleeding Gastroduodenal Ulcers
Status: COMPLETED
Conditions: Ulcer Hemorrhage
Interventions: COMBINATION_PRODUCT: Complex endoscopic treatment with the use of granular sorbent aseptisorb-A and autoplasm enriched with platelets|PROCEDURE: Traditional methods of endoscopic hemostasis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Post Marketing Surveillance (PMS) Study of Ryzodeg™ (Insulin Degludec/Insulin Aspart) in Patients With Diabetes Mellitus in Routine Clinical Practice in India
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/insulin aspart
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p