pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Transcutaneous Tibial Nerve Stimulation for Urgency Urinary Incontinence
Status: ACTIVE_NOT_RECRUITING
Conditions: Urge Incontinence|Overactive Bladder
Interventions: DEVICE: transcutaneous tibial nerve stimulation (TTNS)|DEVICE: transcutaneous electrical stimulation (TENS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Baricitinib in Participants With Systemic Lupus Erythematosus (SLE-BRAVE II)
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Baricitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Relation Between Abdominal Obesity, Type 2 Diabetes Mellitus and Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DIAGNOSTIC_TEST: knee ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Evaluation of Bone Architecture and Bone Strength in Adults With Hypophosphatasia (HPP)
Status: UNKNOWN
Conditions: Hypophosphatasia (HPP)
Interventions: OTHER: Microindentation|OTHER: High resolution peripheral quantitative computed tomography (HRpQCT)|BIOLOGICAL: Biochemical analysis of different bone markers.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1/2 Study of VX-670 in Adult Participants With Myotonic Dystrophy 1 (DM1)
Status: RECRUITING
Conditions: Myotonic Dystrophy Type 1 (DM1)
Interventions: DRUG: VX-670|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Electromyography With Bio-Feedback for the Treatment of Craniomandibular Disorders
Status: COMPLETED
Conditions: Craniomandibular Dysfunction|Orofacial Pain
Interventions: DEVICE: Grindcare|DEVICE: Michigan-type occlusal splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Molecular Biomarker Studies in RAI1 (Retinoic Acid-Induced 1) -Related Disorders
Status: RECRUITING
Conditions: RAI1 Gene 17P11.2 Deletion+Duplication
Interventions: DIAGNOSTIC_TEST: Electroencephalography/Polysomnography (EEG/PSG)|PROCEDURE: Skin Biopsy|DIAGNOSTIC_TEST: Blood draw
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Independence in Self Care - A Program Focused on Nursing Care
Status: UNKNOWN
Conditions: Activities of Daily Living|Hospitalization|Nursing Care|Functional Impairment
Interventions: BEHAVIORAL: Promoting independence in self-care|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety Study of Infanrix Hexa in Healthy Infants Born to Mothers Vaccinated With Boostrix™ During Pregnancy or Immediately Post-delivery
Status: COMPLETED
Conditions: Acellular Pertussis|Tetanus|Poliomyelitis|Diphtheria|Diphtheria-Tetanus-aPertussis-Hepatitis B-Poliomyelitis-Haemophilus Influenzae Type b Vaccines
Interventions: BIOLOGICAL: Infanrix hexa|DRUG: Prevnar13
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Malay Glaucoma Eye Study II Navigation, Mobility and Reading Ability in Primary Glaucoma
Status: UNKNOWN
Conditions: Primary Open Angle Glaucoma|Primary Angle Closure Glaucoma
Interventions: OTHER: Visual rehabilitation module: navigation and mobility|OTHER: Visual rehabilitation module: exercise|OTHER: Visual rehabilitation module: reading
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Trial of Neupro® (Rotigotine Transdermal Patch) in Patients With Parkinson's Disease Undergoing Surgery
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Rotigotine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A RCT of Low MBO Drainage Strategies
Status: RECRUITING
Conditions: Jaundice, Obstructive|Cholangiopancreatography, Endoscopic Retrograde|Endoscopic Ultrasound-Guided Drainage
Interventions: PROCEDURE: EUS-BD|PROCEDURE: ERCP-BD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Xiaoshuanchangrong (XSCR) Capsule for the Treatment of Patients Who Have Suffered From a Stroke
Status: UNKNOWN
Conditions: Acute Ischemic Stroke
Interventions: DRUG: XSCR capsule (Composed of Traditional Chinese Medicine Huangqi, Chuanxiong, Chishao, Danggui, Dilong, Taoren, Honghua.)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Human Amniotic Membrane(s) On Venous Leg Ulcers In an Elderly Population
Status: NOT_YET_RECRUITING
Conditions: Venous Leg Ulcer
Interventions: DEVICE: Membrane-Wrap Lite™|DEVICE: CT-Shield™|DEVICE: Membrane Wrap™|DEVICE: Membrane Wrap - Hydro™|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin Treatment to Attenuate the Progression of Cardiovascular Disease in Hemodialysis Patients
Status: COMPLETED
Conditions: Vascular Calcification|Atherosclerosis|Dyslipidemia|Inflammation
Interventions: DRUG: atorvastatin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Maintenance Bevacizumab Only or Bevacizumab Plus Metronomic Chemotherapy in Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Maintenance:BEVACIZUMAB|DRUG: Maintenance:BEVACIZUMAB+CAPECITABINE+CYCLOPHOSPHAMIDE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Cromones on Eucapnic Hyperventilation (EVH)-Test in Young (Elite) Athletes Who Tested Positive for EIB.
Status: TERMINATED
Conditions: Exercise-Induced Bronchoconstriction
Interventions: DRUG: Sodium Cromoglycate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Magnesium Loading in Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Magnesium Sulfate 2 grams
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acid in Treating Patients With Stage I-III Breast Cancer
Status: COMPLETED
Conditions: Ductal Breast Carcinoma in Situ|Lobular Breast Carcinoma in Situ|Male Breast Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: DRUG: omega-3 fatty acid|OTHER: placebo|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bendamustine Hydrochloride Injection for Initial Treatment of Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Bendamustine hydrochloride injection|DRUG: Chlorambucil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Six-week Flexible Dose Study Evaluating the Efficacy and Safety of Geodon in Patients With Bipolar I Depression.
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Placebo|DRUG: Geodon (Ziprasidone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pentoxifylline and Vitamin E on Pregnancy Rate in Infertile Women Treated by ICSI:
Status: UNKNOWN
Conditions: Infertility, Female
Interventions: DRUG: pentoxifylline|DRUG: Vit E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Food Effect of TP-05 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TP-05 (lotilaner oral), fasted group|DRUG: TP-05 (lotilaner oral), high-fat group|DRUG: TP-05 (lotilaner oral), low-fat group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Management for Cystoscopy: A Prospective Randomized Study Focused on Understanding the Role of the "Bag Squeeze" to Manage Pain for Patients Undergoing Cystoscopy
Status: COMPLETED
Conditions: Pain, Procedural
Interventions: PROCEDURE: Bag Squeeze|PROCEDURE: No Bag Squeeze
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Syndrome--Pediatric Heart Network
Status: COMPLETED
Conditions: Marfan Syndrome
Interventions: DRUG: Losartan Potassium|DRUG: Atenolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioural and Physiological Responses to Dog Visits in Nursing Homes
Status: ACTIVE_NOT_RECRUITING
Conditions: Physiological Responses|Behavior|Mood
Interventions: BEHAVIORAL: Dog visits/control visits|BEHAVIORAL: Control visits/dog visits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: High Selective Subiculum SEEG Guided RF-TC for mTLE-HS
Status: NOT_YET_RECRUITING
Conditions: Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis|Epilepsy
Interventions: PROCEDURE: Subiculum RF-TC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Date Seeds Coffee on Mood and Cognitive Performance
Status: COMPLETED
Conditions: Health Status
Interventions: DIETARY_SUPPLEMENT: Date coffee|DIETARY_SUPPLEMENT: Normal coffee|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: DIGITal mOnitoring afTer Af abLation
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Fibrillation Recurrent|PVI
Interventions: DIAGNOSTIC_TEST: Digital Monitoring|DIAGNOSTIC_TEST: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hepatitis B Vaccination (HBV) in HIV Infected Children
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Intradermal HBV 1 course|BIOLOGICAL: Intramuscular HBV I course
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sleep Disorders Prior to and During a Course of Radiotherapy for Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer Female
Interventions: DIAGNOSTIC_TEST: self-rating scale for severity of sleep disorders|DIAGNOSTIC_TEST: self-rating scale for distress caused by sleep disorders
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Durolane Versus Methylprednisolone in Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Durolane is a device, methylprednisolone in a drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Appendectomy for Uncomplicated Appendicitis: Does Antimicrobial Prophylaxis Really Matter?
Status: UNKNOWN
Conditions: Appendicitis
Interventions: DRUG: cefamezin 1g IV|DRUG: metronidazole 500 mg IV|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ABC Mental Health: A Behavioral Study of K-12 Teachers and School Staff
Status: COMPLETED
Conditions: Mental Health Wellness 1|Burnout, Professional|Self Efficacy
Interventions: BEHAVIORAL: Cultivating Awareness and Resilience in Education (CARE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of SL77.0499-10 (Alfuzosin) Versus Placebo and Tamsulosin in Japanese Patients With Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: DRUG: alfuzosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extending CPAP Therapy in Stable Preterm Infants to Increase Lung Growth and Function
Status: ACTIVE_NOT_RECRUITING
Conditions: Neonatal|Premature Birth|Respiratory Distress Syndrome
Interventions: OTHER: Additional 2 weeks of CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Shadow for All, a Citizenship Science Study to Promote the Prevention of Skin Cancer
Status: NOT_YET_RECRUITING
Conditions: Skin Cancer
Interventions: BEHAVIORAL: Adhesion to the use of collective shadow|BEHAVIORAL: Adhesion to the use of sun protector|BEHAVIORAL: Adhesion to the use of the information disposed in the infographic|BEHAVIORAL: Adhesion to the health literacy sessions in the interventional groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Distraction on Adenoma Detection Rate
Status: COMPLETED
Conditions: Adenoma
Interventions: PROCEDURE: Air insufflation|PROCEDURE: water immersion|PROCEDURE: Water exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Autologous Peripheral Nerve Grafts Into the Substantia Nigra of Subjects With PD Undergoing Deep Brain Stimulation
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: PROCEDURE: Implantation of the Peripheral Nerve Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Auditory Training and Combined Auditory-working-memory Training in Improving Communication in Older Adults
Status: NOT_YET_RECRUITING
Conditions: Hearing Loss
Interventions: BEHAVIORAL: Auditory-working memory training program|BEHAVIORAL: Auditory training program|BEHAVIORAL: Mindfulness training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Simvastatin in Reducing Pancreatitis in Patients With Recurrent, Acute or Chronic Pancreatitis
Status: COMPLETED
Conditions: Acute Pancreatitis
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Placebo Administration|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Use of Sunscreen Starting on the First Day After Ablative Fractional Skin Resurfacing
Status: UNKNOWN
Conditions: PIH
Interventions: OTHER: Sunscreen|OTHER: Vaseline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Study to Evaluate MACE in Patients With Prostate Cancer Treated With Relugolix or Leuprolide Acetate
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Relugolix|DRUG: Leuprolide Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CHOlesterol Lowering and Residual Risk in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Statin|DRUG: PCSK9 inhibitor|DRUG: Ezetimibe 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The PediQUEST Study: Evaluation of Pediatric Quality of Life and Evaluation of Symptoms Technology
Status: COMPLETED
Conditions: Pediatric Neoplasm|Quality of Life|Outcome Assessment|Palliative Care
Interventions: OTHER: Routine Data collection|OTHER: Feedback of patient-reported outcomes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Establishment of Reproductive Cohort and Prediction Model of Genetic Counseling for Mitochondrial Genetic Diseases
Status: NOT_YET_RECRUITING
Conditions: Mitochondrial Diseases
Interventions: OTHER: Biological samples such as blood, urine, oral epithelial cells and nails of carriers were collected, and the mitochondrial DNA mutation heterogeneity level was determined.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Infectious Diseases Specialists on the Appropriateness of Antimicrobial Therapy in Emergency Wards
Status: COMPLETED
Conditions: Patients Under Antimicrobial Therapy
Interventions: OTHER: Infectious disease specialist advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy of F16IL2 and Doxorubicin in Solid Tumour Patients
Status: TERMINATED
Conditions: Advanced Solid Tumor|Breast Cancer
Interventions: DRUG: F16IL2 in combination with doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Switching From Tenofovir Disoproxil Fumarate to Abacavir or Tenofovir Alafenamide
Status: UNKNOWN
Conditions: Renal Insufficiency,Chronic|Hiv|Therapeutic Agent Toxicity
Interventions: DRUG: tenofovir alafenamide|DRUG: abacavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic and Molecular Mechanisms in Assessing Response in Patients With Prostate Cancer Receiving Enzalutamide Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Malignant Neoplasm in the Bone|Metastatic Malignant Neoplasm in the Soft Tissues|Metastatic Prostate Adenocarcinoma|Recurrent Prostate Carcinoma|Stage III Prostate Adenocarcinoma AJCC v7|Stage IV Prostate Adenocarcinoma AJCC v7
Interventions: DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Four Injectable Neuromodulators in the Glabella Area Glabella Area
Status: COMPLETED
Conditions: Cosmetic Techniques
Interventions: DRUG: Onabotulinumtoxina for Injection|DRUG: Abobotulinumtoxina for Injection|DRUG: IncobotulinumtoxinA for Injection|DRUG: PrabotulinumtoxinA for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-based Emotional Regulation Versus ACT in Anxiety
Status: UNKNOWN
Conditions: Anxiety
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy (ACT)|BEHAVIORAL: Mindfulness-based Emotional Regulation (MER)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years
Status: RECRUITING
Conditions: Motor Function|Cognitive Function|Contrast Media
Interventions: PROCEDURE: Motor Tests|PROCEDURE: Cognitive Tests|PROCEDURE: Unenhanced-MRI of the brain|PROCEDURE: Gadolinium Measurements|DRUG: Gadoxetate disodium|DRUG: Gadobenate dimeglumine|DRUG: Gadodiamide|DRUG: Gadoterate meglumine|DRUG: Gadobutrol|DRUG: Gadoteridol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Find Out if Cream V61-044 Used to Treat Fungal Infections Causes an Allergic Skin Reaction to Sunlight in Healthy Participants
Status: COMPLETED
Conditions: Dermatitis, Photoallergic
Interventions: DRUG: Butenafine HCl 1% (BAY1896425) - Induction Phase|DRUG: Butenafine HCl 1% (BAY1896425) - Challenge Phase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Sleep Endoscopy Under Hypnosis in a Sleep Center
Status: COMPLETED
Conditions: Drug Induce Sleep Endoscopy|Hypnosis|Obstructive Sleep Apnea Syndrome
Interventions: PROCEDURE: Drug induce sleep endoscopy of upper aerodigestive tract under hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study of Carbon Dioxide Exchange Patterns During Robotic Prostatectomies
Status: COMPLETED
Conditions: Prostate Cancer|Pneumoperitoneum
Interventions: DEVICE: AirSeal System|DEVICE: Standard Endopath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Panobinostat Maintenance After HSCT fo High-risk AML and MDS
Status: TERMINATED
Conditions: Acute Myeloid Leukaemia (AML)|Myelodysplastic Syndromes (MDS)
Interventions: DRUG: Panobinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transfusion Strategy in Hematological Intensive Care Unit
Status: UNKNOWN
Conditions: Transfusion Related Complication
Interventions: DRUG: Single red blood packed cells Transfusion|DRUG: Two packed red blood cells Transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serotonin and the Upper Airway in Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Paroxetine|DRUG: 5HTP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: BRINK (BRain In Kidney Disease) Memory Study 2.0
Status: UNKNOWN
Conditions: Chronic Kidney Diseases|Dementia|Dementia, Vascular|Stroke|Alzheimer Disease|Cognitive Decline|Cognitive Impairment|Cognitive Dysfunction|Kidney Diseases|Diabetes|Cerebral Atrophy|Small Vessel Ischemic Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1 Trial of CD25/Treg-depleted DLI Plus Ipilimumab for Myeloid Disease Relapse After Matched-HCT
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes|Myeloproliferative Neoplasms|Chronic Myelomonocytic Leukemia|Myelofibrosis
Interventions: DRUG: Ipilimumab|BIOLOGICAL: CD25hi Treg depleted DLI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Booster Dose of Pneumococcal Vaccine Formulations in Young Adults
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Pneumococcal vaccine GSK2189242A (formulation 1)|BIOLOGICAL: Pneumococcal vaccine GSK2189242A (formulation 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effect of a Dual CYP2C19 and CYP3A4 Inhibitor, Fluconazole, on the Pharmacokinetics of Fedratinib in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Fedratinib|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two New Generation Dressings in Intensive Care (ADVANCED)
Status: COMPLETED
Conditions: Complication of Catheter
Interventions: DEVICE: Current hospital dressing|DEVICE: 3M™ IV Advanced Securement dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of CD4-Targeted Chimeric Antigen Receptor T-Cells (CD4- CAR-T) in Subjects With Relapsed or Refractory T-Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: T-Cell Lymphoma|Peripheral T-Cell Lymphoma Refractory|Cutaneous T-Cell Lymphoma Refractory|Cutaneous T-Cell Lymphoma Recurrent|Peripheral T-Cell Lymphoma Recurrent
Interventions: BIOLOGICAL: LB1901
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy and Safety of Large Neutral Amino Acids in the Treatment of Classical Phenylketonuria
Status: NOT_YET_RECRUITING
Conditions: Brain Diseases|Brain Diseases, Metabolic|Brain Diseases, Metabolic, Inborn|Genetic Diseases, Inborn|Metabolism, Inborn Errors|Amino Acid Metabolism, Inborn Errors|Metabolic Disease|Phenylketonurias
Interventions: OTHER: PreKUnil® LNAA Medical Food for PKU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Anti-Cancer Drug Darolutamide in Patients With Testosterone-driven Salivary Gland Cancers
Status: RECRUITING
Conditions: Locally Advanced Salivary Gland Carcinoma|Metastatic Salivary Gland Carcinoma|Recurrent Salivary Gland Carcinoma|Unresectable Salivary Gland Carcinoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Darolutamide|DRUG: Leuprolide Acetate|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acoustic Waveform Respiratory Evaluation
Status: NOT_YET_RECRUITING
Conditions: Asthma|COPD|Cystic Fibrosis|Ciliary Motility Disorders|Bronchiectasis|Airway Malacia|Healthy Control
Interventions: DIAGNOSTIC_TEST: AWARE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Reducing Pain of Lidocaine Injection
Status: COMPLETED
Conditions: Pain of Anesthesia at Breast Biopsy
Interventions: DRUG: 1% Lidocaine|DRUG: 1% Lidocaine plus sodium bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Study to Compare Efficacy and Safety of an Ovule Containing Terconazole, Clindamycin and Fluocinolone Versus an Ovule Containing Metronidazole, Nystatin and Fluocinolone in the Treatment of Secondary Vulvar/ or Vaginal Symptoms of Infectious Vaginitis/ and Infectious Vaginosis
Status: COMPLETED
Conditions: Vaginitis|Infectious Vaginosis
Interventions: DRUG: Gynoclin V|DRUG: Vagitrol V
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spectroscopy Versus Standard Care in Cervical Cancer Patients
Status: TERMINATED
Conditions: Cervical Cancer
Interventions: PROCEDURE: Fluorescence Spectroscopy|PROCEDURE: Colposcopy|PROCEDURE: LEEP Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Lower Limb Immobilisation With Cast and Orthosis
Status: RECRUITING
Conditions: Venous Stasis|Deep Venous Thrombosis
Interventions: DEVICE: Orthosis VACOped|DEVICE: Below knee cast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Qp/Qs Ratio by Noninvasive Methods in Children With Shunt Dependent Pulmonary Circulation
Status: TERMINATED
Conditions: Anesthesia, General|Congenital Heart Disease|Blood Gas Monitoring, Transcutaneous|Blood Gas Analysis
Interventions: OTHER: Qp/Qs ratio monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cetuximab in Combination With Chemotherapy for Patients With Head and Neck Cancer
Status: WITHDRAWN
Conditions: Head and Neck Neoplasms
Interventions: DRUG: Cetuximab|DRUG: Carboplatin|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Effectiveness Study of PTSD Treatments Among Sexual and Gender Minority Populations
Status: NOT_YET_RECRUITING
Conditions: PTSD
Interventions: BEHAVIORAL: Cognitive Processing Therapy|BEHAVIORAL: STAIR Narrative Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Fasiglifam (TAK-875) to Placebo and Sitagliptin in Combination With Metformin in Participants With Type 2 Diabetes
Status: TERMINATED
Conditions: Glycemic Control
Interventions: DRUG: Fasiglifam (TAK-875)|DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-human Study to Assess the Safety, Tolerability and Immunogenicity of the Adjuvanted Universal Influenza Vaccine fH1/DSP-0546LP
Status: RECRUITING
Conditions: Influenza
Interventions: BIOLOGICAL: fH1 2 ug|BIOLOGICAL: fH1 8 ug|BIOLOGICAL: DSP-0546LP 2.5 ug|BIOLOGICAL: DSP-0546LP 5 ug|BIOLOGICAL: DSP-0546LP 10 ug|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Anti-gravity Treadmill Training in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BEHAVIORAL: Anti-gravity treadmill|BEHAVIORAL: Conventional treadmill|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab With Lanreotide Depot for Gastroenteropancreatic Neuroendocrine Tumors
Status: COMPLETED
Conditions: Gastroenteropancreatic Neuroendocrine Tumors
Interventions: DRUG: Lanreotide|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Titanium-Sapphire Laser Trabeculoplasty in Glaucoma: A Randomized Study Comparing Titanium-Sapphire With Argon Laser Trabeculoplasty in Open-Angle Glaucoma Patients
Status: COMPLETED
Conditions: Glaucoma, Open-Angle
Interventions: PROCEDURE: Titanium Sapphire laser trabeculoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: ACT Workshops: A Novel Delivery Modality to Increase Access to Care for Rural Veterans
Status: COMPLETED
Conditions: Access to Care|Psychological Distress
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy (ACT) Workshop|BEHAVIORAL: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RADIOSO MILAN I (RADar Reflector localisatiOn-SCOUT for carcinOma Mammae, the MILAN IEO Experience I)
Status: RECRUITING
Conditions: Breast Cancer|Occult Breast Carcinoma
Interventions: DEVICE: SCOUT® Radar occult breast lesion Localization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Trial of Curcumin to Reduce Mucositis in Autologous Transplant Setting
Status: RECRUITING
Conditions: Oral Mucositis (Ulcerative)
Interventions: DRUG: Curcumin Lozenges|OTHER: Placebo Lozenges
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Investigational Study of Experimental Medication BMS-986165 in Healthy Participants to Study Electrocardiogram Effects
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus|Healthy Participants
Interventions: DRUG: BMS-986165|DRUG: Moxifloxacin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Delivery of Adaptive Natural Killer (NK) Cells (FATE-NK100) With Intraperitoneal Int
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: BIOLOGICAL: FATE-NK100|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of QR-010 in Homozygous ΔF508 Cystic Fibrosis Patients
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: QR-010|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Pharmacokinetics of APT-1011 in Subjects With Eosinophilic Esophagitis (EoE)
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: APT-1011|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Of Epidural Analgesia Techniques In Percutaneous Nephrolithotomy With Surgical Pleth Index
Status: NOT_YET_RECRUITING
Conditions: Analgesia
Interventions: PROCEDURE: TRADITIONAL EPIDURAL|PROCEDURE: DURAL PUNCTURE EPIDURAL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 'Questions About Quitting' Smoking Cessation Trial
Status: COMPLETED
Conditions: Smoking
Interventions: BEHAVIORAL: Message Tone|BEHAVIORAL: Navigation|BEHAVIORAL: Proactive Outreach|BEHAVIORAL: Testimonials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: COMBINATION OF LYMPHATICO-VENULAR ANASTOMOSIS AND LIPOSUCTION IN TREATING LYMPHEDEMA
Status: ENROLLING_BY_INVITATION
Conditions: Description of an Effective Surgical Strategy to Treat Cancer Related Lymphedema, a High Incidence Pathology
Interventions: PROCEDURE: LVA and liposuction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Elacestrant for Treating ER+/HER2- Breast Cancer Patients With ctDNA Relapse (TREAT ctDNA)
Status: RECRUITING
Conditions: ER-positive Breast Cancer|HER2-negative Breast Cancer|Stage IIB Breast Cancer|Stage III Breast Cancer
Interventions: DRUG: Elacestrant|DRUG: Tamoxifen|DRUG: Letrozole 2.5mg|DRUG: Anastrozole 1mg|DRUG: Exemestane 25 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Diffusion Tensor Imaging and High Frequency 3D Endovaginal Ultrasound
Status: ACTIVE_NOT_RECRUITING
Conditions: Pelvic Floor Dysfunction
Interventions: DIAGNOSTIC_TEST: MRI indlcuding DTI|DIAGNOSTIC_TEST: Pelvic floor ultrasound.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Multi-Center Clinical Study of Tang Shen Prescription on Type 2 Diabetic Kidney Disease in Early Stage
Status: UNKNOWN
Conditions: Diabetic Kidney Disease
Interventions: DRUG: Tangshen Prescription|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: rTMS in Children and Adolescents With ADHD:
Status: NOT_YET_RECRUITING
Conditions: ADHD
Interventions: DEVICE: rTMS (repetitive transcranial magnetic stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Serial Amnioinfusions as Regenerative Therapy for Pulmonary Hypoplasia
Status: RECRUITING
Conditions: Renal Failure Congenital|Congenital Renal Anomaly Nos|Renal Agenesis and Dysgenesis|Lower Urinary Tract Obstructive Syndrome
Interventions: DRUG: Lactated Ringers Solution for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Safety of BAY 63-2521, How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug Given as a Single Oral Dose of 1 mg Tablet in Participants With Renal Impairment and Healthy Participants Matched for Age-, Gender-, and Weight
Status: COMPLETED
Conditions: Clinical Pharmacology
Interventions: DRUG: Riociguat (Adempas, BAY 63-2521)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Inhalation of Ciclesonide for Patients With COVID-19: A Randomised Open Treatment Study (HALT COVID-19)
Status: UNKNOWN
Conditions: Covid-19|Pneumonia, Viral|Sars-CoV2
Interventions: DRUG: Ciclesonide Inhalation Aerosol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Imaging to Understand the Role of Inflammation in N-Acetyl Cysteine (NAC) Treatment of Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Disorder|Depression
Interventions: DRUG: N-acetyl cysteine (NAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pharmacokinetics of Sotorasib in Healthy Participants and Participants With Moderate or Severe Hepatic Impairment
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Sotorasib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of 3 Days and 7 Days Intravenous Ceftriaxone Prophylaxis for Variceal Bleeding
Status: COMPLETED
Conditions: Esophageal and Gastric Varices|Gastrointestinal Hemorrhage
Interventions: DRUG: ceftrioxone|DRUG: ceftrioxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Adjuvant Effect of HPV Vaccination on Recurrence of Cervical Precancer or Carcinoma in Women Undergoing Conization
Status: RECRUITING
Conditions: Cervical Intraepithelial Neoplasia Grade 2/3|Recurrence
Interventions: BIOLOGICAL: vaccination against human papillomavirus infection (HPV vaccination)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Kids 2 Be & Breathe: A Study on the Use of Yoga and Mindfulness in Children With Severe Asthma (K2B2)
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: Yoga and Mindfulness Skills
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: To Evaluate the Immunogenicity and Safety of Inactivated Hepatitis A Vaccine
Status: COMPLETED
Conditions: Hepatitis A Vaccine
Interventions: BIOLOGICAL: Inactivated hepatitis A vaccine|BIOLOGICAL: Havrix Inj
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Biomarker Evaluation Trial of UAB30 in Renal Transplant Recipients at High Risk for Non-melanoma Skin Cancer
Status: WITHDRAWN
Conditions: Non-melanoma Skin Cancer
Interventions: DRUG: UAB30|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Unrelated Umbilical Cord Blood Microtransplantation in Patients With Higher-risk MDS
Status: RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: BIOLOGICAL: Unrelated Umbilical Cord Blood|DRUG: Venetoclax|DRUG: Decetabine|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Luchtbrug Junior: the Next Step
Status: NOT_YET_RECRUITING
Conditions: eHealth|Telemedicine|Wheezing
Interventions: OTHER: Luchtbrug Junior (online monitoring)|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BAY59-7939, Japanese Phase II in Atrial FibrillationTrial Status
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Rivaroxaban (BAY59-7939)|DRUG: Rivaroxaban (BAY59-7939)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Liquid Biopsy in Monitoring the Neoadjuvant Chemotherapy and Operation in Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer|Gastro-oesophageal Junction Cancer
Interventions: DRUG: Neoadjuvant chemotherapy with PSOX regimen.|OTHER: Detect the imaging data and levels of CTC, ctDNA, cfDNA, CEA, CA19-9, CA72-4 in plasma.|OTHER: Detect the tumor related DNA in pathological tissues after operation.|OTHER: Follow-up of DFS and OS in patients with gastric cancer after operation.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Interferential Current on Edema, Pain and Muscle Strength in Patients With Distal Radius Fracture
Status: COMPLETED
Conditions: Radius Fractures|Edema|Pain
Interventions: DEVICE: Electrotherapy, interferential current|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Terazosin and Parkinson's Disease Extension Study
Status: RECRUITING
Conditions: Symptomatic Parkinson Disease|REM Sleep Behavior Disorder|Pre-motor Parkinson's Disease
Interventions: DRUG: Terazosin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiotherapy and Action-Observation Therapy: An Integrated Approach for Upper Limb Impairment in Subacute Stroke
Status: WITHDRAWN
Conditions: Stroke
Interventions: DEVICE: Virtual Reality|DEVICE: Action Observation Therapy|DEVICE: Landscape video|OTHER: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NCARE, Transition to Recovery
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Withdrawal|Substance Use Disorders
Interventions: BEHAVIORAL: Patient navigation|BEHAVIORAL: Motivational interviewing (MI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of LMA-Supreme and I-gel for the Incidence of Postoperative Sore Throat
Status: TERMINATED
Conditions: General Anesthesia
Interventions: DEVICE: LMA supreme|DEVICE: I-gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Co-administration of Meningococcal Vaccine GSK134612 and Pneumococcal Vaccine GSK1024850A vs Individual Administration
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Meningococcal vaccine GSK134612|BIOLOGICAL: Pneumococcal vaccine GSK1024850A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Suvorexant as an Adjunct to Buprenorphine in Persons Who Use Fentanyl
Status: RECRUITING
Conditions: Suvorexant|Placebo|Opioid Use Disorder
Interventions: DRUG: Suvorexant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Stimulation & Generalized Anxiety Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Anxiety|Generalized Anxiety Disorder|Generalized Anxiety
Interventions: DEVICE: Cranial Electrotherapy Stimulator (CES) Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Ruxolitinib Evaluation in Chronic Hand Eczema Study 1
Status: WITHDRAWN
Conditions: Hand Eczema
Interventions: DRUG: Ruxolitinib cream|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT