pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of Nilotinib in Adult Patients With Imatinib Resistant or - Intolerant Chronic Myeloid Leukemia in Blast Crisis, Accelerated Phase or Chronic Phase
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of DS-8500a in Japanese Subjects With Type 2 Diabetes Mellitus (T2DM)
Status: COMPLETED
Conditions: Type2 Diabetes Mellitus
Interventions: DRUG: DS-8500a|DRUG: Sitagliptin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preemie Prep For Parents (P3): Home Antenatal Prematurity Education
Status: COMPLETED
Conditions: Premature Birth|Decision Making|Prenatal Care|Resuscitation|Infant, Premature
Interventions: OTHER: Preemie Prep for Parents (P3) Outpatient Mobile Intervention|OTHER: ACOG links
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: FID-007 and Cetuximab in Treating Patients With Advanced Head and Neck Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: FID007
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Open, Controlled, Multicenter Phase III Clinical Study of Fluzoparib in Combination With Apatinib Versus Investigator-Selected Chemotherapy for HRD-Positive/HER2-negative Advanced Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Fluzoparib|DRUG: Apatinib Mesylate|DRUG: Capecitabine tablets|DRUG: Vinorelbine Tartrate Oral|DRUG: Eribulin mesylate injection|DRUG: Gemcitabine Hydrochloride|DRUG: Paclitaxel-albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel Compared With Observation in Treating Patients Who Have Undergone Radical Prostatectomy for Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: docetaxel|OTHER: active surveillance|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REDECT 2: REnal Masses: Pivotal Trial to DEteCT Clear Cell Renal Cell Carcinoma With PET/CT
Status: WITHDRAWN
Conditions: Renal Cell Carcinoma|Kidney Cancer
Interventions: DRUG: Iodine (124I) Girentuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multimodal Pain Package vs. Regular Formulation for Pain Management in Ambulatory Spinal Surgery
Status: RECRUITING
Conditions: Spinal Disorder
Interventions: DRUG: Acetaminophen|DRUG: Celebrex|DRUG: Gabapentin|DRUG: Famotidine|DRUG: Decadron|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Swedish Study of Liver Transplantation for Non-resectable Colorectal Cancer Metastases
Status: RECRUITING
Conditions: Colorectal Cancer|Liver Metastases|Colorectal Liver Metastases
Interventions: PROCEDURE: Liver transplantation Ltx|OTHER: Best alternative care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methotrexate as Remission Maintenance Therapy After Remission-Induction With Tocilizumab and Glucocorticoids in Giant Cell Arteritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Giant Cell Arteritis
Interventions: DRUG: Methotrexate|DRUG: Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperthermia Combined With Immune Checkpoint Inhibitor Therapy for Advanced Gastrointestinal Tumours
Status: COMPLETED
Conditions: Gastrointestinal Tumor
Interventions: DEVICE: Water-filtered infrared A radiation whole-body hyperthermia (HECKEL 3000MT-4T, Germany)|DRUG: tislelizumab (BeiGene, China) combined with PD-1 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Granisteron Versus Ondansetron for Prophylaxis Against Post-Spinal Anesthesia Shivering: a Randomized Controlled Study
Status: UNKNOWN
Conditions: Spinal Anaesthetic
Interventions: DRUG: Ondansetron 8mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enzastaurin as Second and Third-Line Treatment for Non-Small Cell Lung Cancer.
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: DRUG: Enzastaurin HCL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-operative Intravenous Steroid in Total Knee Replacement for Pain Relief and Recovery
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Methylprednisolone Sodium Succinate|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A RCT to Compare Post-operative Sensitivity of Restorations With Fill-Up, a Dual Curing Composite and Conventional Composite Resin
Status: UNKNOWN
Conditions: Postoperative Sensitivity of Existing Dental Filling Materials
Interventions: DEVICE: Fill-Up composite resin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Allogeneic Bone Marrow Transplantation Following Cyclophosphamide and Radiotherapy in Patients With Myelodysplastic Syndrome and Acute Leukemia Related to Fanconi's Anemia
Status: COMPLETED
Conditions: Fanconi's Anemia|Myelodysplastic Syndromes|Leukemia, Nonlymphocytic, Acute|Leukemia, Lymphocytic, Acute
Interventions: DRUG: cyclophosphamide|PROCEDURE: Allogeneic Bone Marrow Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Community Opioid Innovation Network (JCOIN): TCU Clinical Research Center
Status: RECRUITING
Conditions: Addiction, Opioid
Interventions: BEHAVIORAL: TCU Opioid-Treatment Linkage Model (O-TLM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficiency of an Educational Program for Informal Caregivers of Hospitalized, Dependent Patients: Cluster Randomised Trial
Status: COMPLETED
Conditions: Dependence, Dementias
Interventions: OTHER: Health education intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Brain Trauma Outcomes in Nova Scotia Study
Status: COMPLETED
Conditions: Brain Injuries,Traumatic|Outcome Assessment (Health Care)|Craniocerebral Trauma|Emergency Medical Services|Organizational Innovation
Interventions: BEHAVIORAL: Head Injury Guideline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Single Site Study of the Wettability of Contact Lenses With an Investigational Multi-Purpose Disinfecting Solution vs. a Marketed Multi-Purpose Solution
Status: COMPLETED
Conditions: Contact Lens Care
Interventions: DEVICE: FID 114675A Multi-Purpose Disinfecting Solution (MPDS)|DEVICE: RepleniSH Multi-Purpose Disinfecting Solution (MPDS) (OPTI-FREE® RepleniSH®)|DEVICE: Senofilcon A contact lens (ACUVUE® Oasys™)|DEVICE: Balafilcon A contact lens (PureVision®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cytokine and Visual Outcome Variations in Eyes Receiving Ranibizumab
Status: UNKNOWN
Conditions: Age Related Macular Degeneration|Diabetic Macular Edema|Macular Edema|Retinal Vein Occlusion
Interventions: DRUG: Intravitreal ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the AeriSeal System for HyPerInflation Reduction in Emphysema (ASPIRE)
Status: TERMINATED
Conditions: Pulmonary Emphysema
Interventions: DEVICE: Treatment plus Optimal Medical Therapy|OTHER: Optimal Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Multicentre Trial of Endoscopic Ultrasound Guided Radiofrequency Ablation of Cystic Tumours of the Pancreas
Status: UNKNOWN
Conditions: Pancreatic Cyst
Interventions: PROCEDURE: EUS guided RFA of cystic tumours of the pancreas
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PEMF as Adjunctive Treatment Following Surgical Repair of Full Thickness Rotator Cuff Tears
Status: TERMINATED
Conditions: Full-thickness Rotator Cuff Tear
Interventions: DEVICE: RCStim Model 1114
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spatial Hearing Rehabilitation in Noise for Bilateral Cochlear Implant Children
Status: RECRUITING
Conditions: Cochlear Implantation
Interventions: DIAGNOSTIC_TEST: SPHERE protocol : Spatial hearing performances test|DIAGNOSTIC_TEST: FRASIMAT Test : audiology test of speech in noise perception|DIAGNOSTIC_TEST: Kid SSQ questionnaire of life : The Speech, Spatial and Other Qualities of Hearing Scale|OTHER: spatial hearing rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Sequencing of Anthracyclines and Taxanes for Locally Advanced HER2-negative Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel or Paclitaxel|DRUG: Cyclophosphamide + Doxorrubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Phase I Study to Eval the Safety and Tolerability of a Vaccine (GI-6207) Consisting of Whole, Heat-killed Recombinant Saccharomyces Cerevisiae (Yeast) Genetically Modified to Express CEA Protein in Adults With Metastatic CEA-expressing ...
Status: COMPLETED
Conditions: Prostate Cancer|Breast Cancer|Lung Cancer|Colorectal Cancer|Head and Neck Cancer
Interventions: BIOLOGICAL: GI-6207 [Recombinant Saccharomyces Cerevisia|DRUG: (Yeast CEA Vaccine)(GI-6207[Recombinant Sarrcharomyces Cerevusua-CEA (610D)])
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraductal Radiofrequency Thermoablation and Radiotherapy Combined Treatment for Extrahepatic Cholangiocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Biliary Tract Carcinoma|Radiotherapy|Radio-frequency Ablation
Interventions: PROCEDURE: ID-RFA and Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Brinzolamide/Timolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Preventive Use of Ondansetron in the Cesarean Section Under Spinal Anesthesia
Status: UNKNOWN
Conditions: Adverse Anesthesia Outcome
Interventions: DRUG: Ondansetron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection
Status: COMPLETED
Conditions: HSIL, High-Grade Squamous Intraepithelial Lesions|Human Papilloma Virus Infection|HIV Infection|Anal Cancer|Anus Neoplasms
Interventions: DRUG: ABI-1968
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Preventive Program Against Lifestyle Related Diseases
Status: COMPLETED
Conditions: Type-2 Diabetes|Cardiovascular Diseases|Chronic Obstructive Pulmonary Disease (COPD)
Interventions: BEHAVIORAL: Lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Subcutaneous (Injected Under the Skin) Risankizumab to Assess Change in Disease Symptoms in Adult Participants With Moderate to Severe Plaque Psoriasis With Palmoplantar Involvement
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Placebo for Risankizumab|DRUG: Risankizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of the RIGHTEST Continuous Glucose Monitoring System for Blood Glucose Management in Persons With Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus|Type 1 Diabetes|Type 2 Diabetes
Interventions: DEVICE: RIGHTEST Continuous Glucose Monitoring System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Subretinal Implantation of Human Embryonic Stem Cell-Derived RPE Cells in Advanced Dry AMD
Status: UNKNOWN
Conditions: Dry Macular Degeneration|Geographic Atrophy
Interventions: BIOLOGICAL: CPCB-RPE1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: High-flow Nasal Cannula Oxygenation Decrease Hypoxia in Sedated Gastrointestinal Endoscopes in Obesity
Status: RECRUITING
Conditions: Hypoxia|Gastric Cancer|Esophagus Cancer|Polyp of Colon|Colon Cancer
Interventions: DEVICE: High-flow nasal cannula oxygenation|DEVICE: Regular nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Pharmacokinetics, Safety and Tolerability After a Single Dose Administration of JNJ-31001074 in Pediatric Patients (12-17 Years) With Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Attention Deficit Disorders With Hyperactivity
Interventions: DRUG: JNJ-31001074
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cefepime and Unictam on Preventing Post-Cesarean Surgical Site Infections
Status: ACTIVE_NOT_RECRUITING
Conditions: Cesarean Section; Infection
Interventions: DRUG: Cefepime 1000 MG|DRUG: Ampicillin-sulbactam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Lung Ultrasound-Guided Fluid Deresuscitation in ICU Patients
Status: RECRUITING
Conditions: Mechanical Ventilation|Fluid Overload|Deresuscitation|Ventilator-free Days
Interventions: OTHER: Lung ultrasound guided deresuscitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy, Safety and Tolerance of Experimental Morning-only MOVIPREP® Bowel Preparation in Comparison With Split-dose With Nocturnal Pause MOVIPREP® Bowel Preparation
Status: COMPLETED
Conditions: Bowel Preparation Prior to Endoscopic, Radiological and Other Examinations as Well as to Surgical Procedures Which Require Empty Bowel.
Interventions: DRUG: MOVIPREP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Coronary Artery and Systemic Autoimmune Disease: Diagnostics and Treatment
Status: COMPLETED
Conditions: Autoimmune Diseases|Coronary Artery Disease
Interventions: DEVICE: Percutaneous coronary intervention with new generation fully resorbable scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intragastric pH and Bismuth Effect for H. Pylori Eradication
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: (A)Bismuth|DRUG: (B)Bismuth|DRUG: (C)Bismuth|DRUG: (D)Esomeprazole and Bismuth|DRUG: (E)Esomeprazole and Bismuth|DRUG: (F)Esomeprazole and Bismuth|OTHER: (G)Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: MILES-02: Study of Chemotherapy Treatment and Toxicity in Elderly Patients With Advanced Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: gemcitabine prolonged continuous infusion|DRUG: cisplatin|DRUG: vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Designed to Assess the Safety, Tolerability and PK of PTI-808 in Healthy Volunteers and in Adults With Cystic Fibrosis
Status: COMPLETED
Conditions: Healthy Volunteer - Complete|Cystic Fibrosis - Complete
Interventions: DRUG: PTI-808|DRUG: Placebo|DRUG: PTI-428|DRUG: PTI-801
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Neoadjuvant Lapatinib in Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: docetaxel+lapatinib|DRUG: docetaxel + trastuzumab|DRUG: docetaxel + trastuzumab + lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided TAPB vs Surgical TAPB With Bupivacaine in Cesarean Section
Status: RECRUITING
Conditions: Cesarean Section|Ultrasound Guided Transversus Abdominis Plane Block|Surgical Transversus Abdominis Plane Block|Bupivacaine|Acute Pain
Interventions: PROCEDURE: surgical TAP block|PROCEDURE: US guided TAP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Astym Technique, the Graston Technique, and Therapeutic Ultrasound in the Treatment of Lateral Epicondylosis.
Status: TERMINATED
Conditions: Lateral Epicondylitis|Tennis Elbow|Posterolateral Rotator Instability
Interventions: PROCEDURE: Therapeutic ultra sound|PROCEDURE: Astym Treatment Technique|PROCEDURE: Graston Treatment Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Genetically Modified T-Cell Therapy in Treating Patients With Advanced ROR1+ Malignancies
Status: TERMINATED
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm|Metastatic Lung Non-Small Cell Carcinoma|Metastatic Triple-Negative Breast Carcinoma|Recurrent Acute Lymphoblastic Leukemia|Recurrent Mantle Cell Lymphoma|Refractory Chronic Lymphocytic Leukemia|Stage III Lung Non-Small Cell Cancer AJCC v7|Stage IIIA Lung Non-Small Cell Cancer AJCC v7|Stage IIIB Lung Non-Small Cell Cancer AJCC v7|Stage IV Breast Cancer AJCC v6 and v7|Stage IV Lung Non-Small Cell Cancer AJCC v7|Unresectable Lung Non-Small Cell Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: ROR1 CAR-specific Autologous T-Lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CF33-hNIS-antiPDL1 for the Treatment of Metastatic Triple Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Metastatic Triple-Negative Breast Carcinoma|Prognostic Stage IV Breast Cancer AJCC v8
Interventions: BIOLOGICAL: Oncolytic Virus CF33-expressing hNIS/Anti-PD-L1 Antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Mirena and Systemic Progestin for Endometrial Hyperplasia
Status: COMPLETED
Conditions: Endometrial Hyperplasia
Interventions: DRUG: Provera (medroxyprogesterone/progestin)|DRUG: Provera (medroxyprogesterone)|DEVICE: Mirena (levonorgestrel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adherence to Otezla
Status: NOT_YET_RECRUITING
Conditions: Psoriasis
Interventions: DRUG: Otezla - Standard Care|BEHAVIORAL: Reminder Text Intervention with apremilast|BEHAVIORAL: Extended Consultation for apremilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: CAP-Ketamine for Antidepressant Resistant PTSD
Status: COMPLETED
Conditions: PTSD|Posttraumatic Stress Disorder
Interventions: DRUG: Ketamine|DRUG: Placebo/Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Intervention in Chronic Fatigue Syndrome
Status: COMPLETED
Conditions: Chronic Fatigue Syndrome
Interventions: DRUG: Rituximab|DRUG: Saline (NaCl 0,9 %) (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biopsy Study Comparing MRI and Ultrasound Soft Image Fusion Guided Biopsies and Gold Standard Prostate Biopsies.
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Biopsies using image fusion|PROCEDURE: Gold standard biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Selinexor and Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Aggressive Non-Hodgkin Lymphoma
Status: UNKNOWN
Conditions: Prolymphocytic Leukemia|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia
Interventions: DRUG: Selinexor|DRUG: Ibrutinib|OTHER: Pharmacological Study|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AFPᶜ³³²T in Advanced HCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Cancer|AFP Expressing Tumors
Interventions: GENETIC: Autologous genetically modified AFPᶜ³³²T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preference Tiotropium Respimat Study in COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: Group1:Spiriva® Respimat®|DEVICE: Group2:Hirobriz®/Oslif®/Onbrez® Breezhaler®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dorsomedial Prefrontal Cortex and the Antidepressant Efficacy of Theta Burst Stimulation in Depressed Patients
Status: COMPLETED
Conditions: Treatment Resistant Depression
Interventions: DEVICE: Active standardized iTBS-DMPFC|DEVICE: Active high-dosage iTBS-DMPFC|DEVICE: Sham standardized iTBS-DMPFC or high-dosage iTBS-DMPFC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease (DED)
Interventions: DRUG: OC-01 (varenicline) nasal spray|DRUG: Placebo (vehicle) nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Combination of Ipilimumab and Fotemustine for Treat Unresectable Locally Advanced or Metastatic Melanoma
Status: COMPLETED
Conditions: Metastatic Malignant Melanoma
Interventions: DRUG: Ipilimumab and Fotemustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conventional Dose Versus High Dose Sequential Chemotherapy for Poor Prognosis Germ Cell Tumors
Status: COMPLETED
Conditions: Testicular Neoplasms|Germ Cell Tumors
Interventions: DRUG: Cyclophosphamide|DRUG: Etoposide|DRUG: Cisplatin|DRUG: Bleomycin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Intervention for Morbidly Obese Patients After Roux-en-Y Gastric Bypass (RYGB) Surgery
Status: TERMINATED
Conditions: Weight Loss|Obesity
Interventions: BEHAVIORAL: Lifestyle counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Er,Cr:YSGG Laser For Recipient Bed Bio-modification And Connective Tissue Harvesting in Treatment of Gingival Recession
Status: COMPLETED
Conditions: Gingival Recession, Localized
Interventions: DEVICE: laser root surface conditioning & laser DGG harvesting|DEVICE: laser root surface conditioning & blade DGG harvesting|PROCEDURE: blade DGG harvesting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Study on the Mangrove Sword Bean Food Bar Effect for Older People
Status: COMPLETED
Conditions: Nutrition Disorders in Old Age|Disaster
Interventions: DIETARY_SUPPLEMENT: Clinical study on the mangrove sword bean food bar effect for older people
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Abt, Concussion Screen Use Recovery Time
Status: RECRUITING
Conditions: Sport-related Concussion
Interventions: BEHAVIORAL: Screen Time Restriction (ST-Restricted)|BEHAVIORAL: Aerobic Exercise (AE)|BEHAVIORAL: Screen-time restricted plus aerobic exercise (STR+AE)|BEHAVIORAL: Stretching Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Feasibility of Confocal Laser Microscopy (CLM)in the Computed Tomography-guided Needle Biopsy of Pulmonary and Mediastinal Lesions
Status: UNKNOWN
Conditions: Pulmonary and Mediastinal Lesions
Interventions: PROCEDURE: confocal laser microscopy CLM at trans thoracic needle biopsy TTNB|DEVICE: CT guided trans thoracic needle biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Radiographic Assessment of the Healing Pattern Associated With Periradicular Endodontic Microsurgery
Status: RECRUITING
Conditions: Periapical; Infection
Interventions: PROCEDURE: Piezo endodontic surgery|PROCEDURE: Conventional endodontic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase I Rising Dose Tolerability Study of SC-48334 in Patients With Acquired Immunodeficiency Syndrome (AIDS) and Advanced AIDS Related Complex
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Butyldeoxynojirimycin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resection of Flexor Digitorum Superficialis Tendon for Severe Trigger Fingers
Status: RECRUITING
Conditions: Trigger Finger|Stenosing Tenosynovitis
Interventions: PROCEDURE: A1 pulley division|PROCEDURE: A1 pulley division + Resection of one or both slips of the FDS tendon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Three School-based Mental Health Preventive Interventions in France
Status: NOT_YET_RECRUITING
Conditions: Emotional Distress|Functional Impairment|Psychosocial Problem|Wellbeing|User Experience
Interventions: BEHAVIORAL: Adapt Module|BEHAVIORAL: Engage Module|BEHAVIORAL: Interact Module|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Venue-Based Couples CoOp in South Africa
Status: COMPLETED
Conditions: Alcoholism|HIV Infections
Interventions: BEHAVIORAL: Couples Intervention|BEHAVIORAL: Women's CoOp|BEHAVIORAL: Women's CoOp and Men's Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Extended Facebook Intervention for Young Sexual and Gender Minority Smokers
Status: COMPLETED
Conditions: Tobacco Use|Smoking|Tobacco Dependence|Tobacco Use Disorder|Tobacco Use Cessation|Tobacco Smoking|Smoking Cessation|Smoking, Cigarette|Smoking, Tobacco
Interventions: BEHAVIORAL: POP-6:|BEHAVIORAL: TSP-6:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients
Status: RECRUITING
Conditions: Breast Cancer|Stage III Breast Cancer|Breast Cancer Female|Stage I Breast Cancer|Stage II Breast Cancer
Interventions: BEHAVIORAL: THRIVE|BEHAVIORAL: Health Education Support Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Catheter-Directed Pulmonary Reperfusion in Treatment of Pulmonary Embolism Patients
Status: UNKNOWN
Conditions: Pulmonary Embolism
Interventions: PROCEDURE: mechanical fragmentation|PROCEDURE: In Situ thrombolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation of Reconstructed Shoulder Rotator Cuff
Status: COMPLETED
Conditions: Full Thickness Rotator Cuff Tear
Interventions: PROCEDURE: Standard physical therapy program PLUS aquatic physical therapy|OTHER: standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Remotely-conducted Trial of Famotidine vs Placebo for Patients at Home With Coronavirus (COVID) of 2019 (COVID-19)
Status: WITHDRAWN
Conditions: Covid19
Interventions: DRUG: Famotidine 20 milligram tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Iodine-131 Anti-B1 Antibody Plus CHOP For Untreated Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Mantle-Cell
Interventions: BIOLOGICAL: Tositumomab and Iodine I 131 Tositumomab followed by CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Intervention With Near Infrared Stimulation
Status: RECRUITING
Conditions: Aging|Parkinson Disease
Interventions: DEVICE: Medx Console System|DEVICE: Sham Medx Console System|DEVICE: Vielight 810 intranasal stand alone unit|DEVICE: Sham Vielight 810 intranasal stand alone unit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise in Patients With Post-Concussion Symptoms
Status: COMPLETED
Conditions: Craniocerebral Trauma|Head Injury, Minor|Postconcussion Syndrome|Posttraumatic Headache|Mild Traumatic Brain Injury
Interventions: BEHAVIORAL: aerobic exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenomics and Post-Operative Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea
Interventions: DRUG: Granisetron|DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare CAUTI Rates Following ERASE CAUTI Tray Silver vs Silver Coated Foley Catheters
Status: TERMINATED
Conditions: Surgery
Interventions: DEVICE: ERASE Silver Coated Foley Catheter|DEVICE: Comparator Silver Coated Catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: FOLFIRI Versus Docetaxel and Cisplatin as a Second-line Chemotherapy After Failure of First-line Chemotherapy in Advanced Gastric Cancer
Status: COMPLETED
Conditions: Inoperable Gastric Cancer
Interventions: DRUG: 5-fluorouracil, irinotecan and leucovorin|DRUG: docetaxel and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Biliary Anastomosis Using Surgical Loupe Versus Microscope in Living Donor Liver Transplantation
Status: COMPLETED
Conditions: Liver Failure|Liver Diseases|Liver Cancer|Liver Neoplasms|Liver Dysfunction
Interventions: OTHER: Surgical Loupes|OTHER: Microscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Exercise Therapy Versus Spinal Manual Therapy in Patients With PFPS
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: PROCEDURE: Local exercise therapy|PROCEDURE: Spinal manual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Individualized Accurate Positioning TMS Based on Task fMRI Activation on Upper Extremity Function After Stroke
Status: UNKNOWN
Conditions: Stroke|Transcranial Magnetic Stimulation|Functional Magnetic Resonance Imaging|Upper Extremity Dysfunction|Brain Plasticity
Interventions: DEVICE: Transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy and Safety of Biphasic Insulin Aspart 30 and Biphasic Human Insulin 30 on Blood Sugar Control in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 30|DRUG: biphasic human insulin 30|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Impacts of Food Supplementation on Malnourished HIV-Infected Adults in Kenya
Status: COMPLETED
Conditions: HIV|Malnutrition|HIV Infections
Interventions: DIETARY_SUPPLEMENT: fortified blended flour - Insta Foundation Plus (with whey protein concentrate)|OTHER: nutrition counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Resveratrol Administration on Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion
Status: COMPLETED
Conditions: Metabolic Syndrome X
Interventions: DRUG: Resveratrol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: In-vivo Effects of E-cigarette Aerosol on Innate Lung Host Defense
Status: TERMINATED
Conditions: Smoking|Healthy
Interventions: OTHER: Cinnamaldehyde e-liquid|OTHER: PG/VG e-liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Myoelectric Computer Interface to Reduce Muscle Co-activation After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: 60-min isometric MyCI training|BEHAVIORAL: 90-min isometric MyCI training|BEHAVIORAL: 90-min movement MyCI training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Efficacy of the AlphaVac Multipurpose Mechanical Aspiration (MMA) F1885 PE for Treatment of Acute Pulmonary Embolism
Status: COMPLETED
Conditions: Pulmonary Embolism|Acute Pulmonary Embolism
Interventions: DEVICE: AlphaVac Multipurpose Mechanical Aspiration (MMA) F1885 PE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Patient Management Practices and Quality of Life With Paricalcitol Capsules in the Treatment of Secondary Hyperparathyroidism in Stage 3-5 Chronic Kidney Disease Patients Not Yet on Dialysis
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism|Chronic Kidney Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Study of CIK Plus S-1 and Bevacizumab as Maintenance Treatment for Patients With Advanced Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Neoplasms
Interventions: BIOLOGICAL: Cytokine-Induced Killer Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fibered Platinum Coils vs Vascular Plugs in Pelvic Varices Embolization for the Treatment of Pelvic Congestion Syndrome
Status: COMPLETED
Conditions: Pelvic Congestion Syndrome
Interventions: DEVICE: Fibered platinum coils|DEVICE: Vascular plugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Assess Two Doses of GSK2402968 in Subjects With Duchenne Muscular Dystrophy (DMD)
Status: COMPLETED
Conditions: Muscular Dystrophies
Interventions: DRUG: GSK2402968 3mg/kg/week|DRUG: GSK2402968 6 mg/kg/week|DRUG: Placebo to match GSK2402968 3 mg/kg/week|DRUG: Placebo to match GSK2402968 6 mg/kg/week
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Carfilzomib vs Best Supportive Care in Subjects With Relapsed and Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Best Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is a Single Daily Session Combining HS + Physio Sufficient to Obtain Long-term Clinical Benefits in Bronchiectasis?
Status: UNKNOWN
Conditions: Bronchiectasis|Airway Clearance Impairment
Interventions: OTHER: Hypertonic saline at 6%|OTHER: Airway clearance techniques (oscillating positive expiratory pressure therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose of Atorvastatin and Circulating Endothelial Microparticles
Status: UNKNOWN
Conditions: Endothelium|Hydroxymethylglutaryl-CoA Reductase Inhibitors
Interventions: DRUG: atorvastatin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QAU145 in Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: QAU145|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Genetic Variation of Dopamine Pathway in Patients With Chronic Pain
Status: COMPLETED
Conditions: Peripheral Neuropathy|Osteoarthritis
Interventions: GENETIC: Blood sampling for genotyping|OTHER: Personality Questionnaires completion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Infant Formula and Toddler Drink Feeding Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Growth
Interventions: OTHER: Control Infant Formula|OTHER: Control Toddler Drink|OTHER: Experimental Infant Formula|OTHER: Experimental Toddler Drink|OTHER: Human Milk|OTHER: Human Milk Supplemental Formula|OTHER: Human Milk Toddler Drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Ibrutinib, Lenalidomide, and Dexamethasone in Treating Patients With Multiple Myeloma Ineligible for Transplant
Status: TERMINATED
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: DRUG: Dexamethasone|DRUG: Ibrutinib|OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|OTHER: Pharmacological Study|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Memory Gel and Shape Combined Cohort
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Breast Augmentation|Primary Breast Reconstruction|Revision Breast Augmentation|Revision Breast Reconstruction
Interventions: DEVICE: MemoryShape® Breast Implants|DEVICE: MemoryGel® Breast Implants|PROCEDURE: Other Aesthetic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acellular Dermal Matrix Graft In Root Coverage of Gingival Recessions With Previously Restored Cervical Lesions
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Root coverage with extended flap technique and acelular dermal matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short- and Long-term Health Effects of Air Pollution in Poland
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Coronary Syndrome|Atrial Fibrillation|Kidney Diseases|Particulate Matter Inhalation Injury|Pollution; Exposure|Oxidative Stress|Ischemic Stroke
Interventions: OTHER: Impact of air pollution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Investigate Safety, Efficacy of an Anti-IFNγ mAb in Children With Primary Haemophagocytic Lymphohistiocytosis
Status: COMPLETED
Conditions: Primary Haemophagocytic Lymphohistiocytosis
Interventions: BIOLOGICAL: NI-0501
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EGFR/B7H3 CAR-T on Lung Cancer and Triple Negative Breast Cancer
Status: RECRUITING
Conditions: EGFR/ B7H3-positive Advanced Lung Cancer|EGFR/ B7H3-positive Advanced Triple-negative Breast Cancer
Interventions: BIOLOGICAL: EGFR/B7H3 CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation in the Treatment of Obsessive Compulsive Disorders
Status: COMPLETED
Conditions: Obsessive Compulsive Disorders
Interventions: PROCEDURE: rTMS-1Hz|PROCEDURE: rTMS-10 Hz|PROCEDURE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Aerosolized, Recombinant Alpha 1-Antitrypsin on Epithelial Lining Fluid Analytes in Subjects With Alpha 1-Antitrypsin Deficiency
Status: COMPLETED
Conditions: Alpha1-antitrypsin Deficiency
Interventions: DRUG: Aerosolized, Recombinant Alpha 1-Antitrypsin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Externally Versus Internally Cooled Tip Catheter Ablation in Paroxysmal Atrial Fibrillation
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Long-term electrical isolation of pulmonary veins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of 2 Doses of MAP0010 and Placebo in Asthmatic Children
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: 0.135mg MAP0010|DRUG: 0.25mg MAP0010|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oxidative-reductive Processes and the Degree of Inflammation in Saliva With Conventional Brackets and Clear Aligners
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammation|Oxidative Stress|TNF-α
Interventions: DIAGNOSTIC_TEST: Saliva samples collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT