pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Diabetes, Exercise and Liver Fat (DELIVER)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Non-Alcoholic Fatty Liver Disease|Obesity|Insulin Resistance|Liver Diseases|Fatty Liver|Diabetes Mellitus|Glucose Metabolism Disorders|Glucose Intolerance|Metabolic Disease
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Obsessive-Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: olanzapine + fluoxetine|DRUG: placebo + fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of Lateral Heel Wedges of Osteoarthritis of the Knee
Status: TERMINATED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Wedge Insert|OTHER: Flat Insert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effectiveness of Lung Expansion Therapy in Adult Human Subjects
Status: COMPLETED
Conditions: Atelectasis
Interventions: DEVICE: Incentive Spirometry|DEVICE: EzPAP® Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Randomized Study of Not Giving Diphteria-tetanus-pertussis Vaccination With or After Measles Vaccination
Status: COMPLETED
Conditions: Mortality|Hospitalization|Adverse Events
Interventions: BIOLOGICAL: DTP3/4+OPV+MV versus OPV+MV or DTP4+OPV4 versus OPV4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Comparison of Effect of Postoperative Cyclosporine A 2% Ophthalmic Emulsion and Betamethasone Eye Drop on Surgical Success of Trabeculectomy Procedure
Status: COMPLETED
Conditions: Glaucoma, Open Angle
Interventions: DRUG: Cyclosporine|DRUG: Betamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Characterizing Emmer Seeds and Flours, and Determining the Glycemic Effects of Emmer Breads
Status: COMPLETED
Conditions: Potential Abnormality of Glucose Tolerance|Appetitive Behavior
Interventions: OTHER: Glucose as reference food|OTHER: Emmer bread from Greek emmer|OTHER: Emmer bread from Italian emmer|OTHER: Whole wheat commercial bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: IMPACTS Trial: Investigation of the Modulation of Phospholipase in Acute Chest Syndrome
Status: COMPLETED
Conditions: Sickle Cell Disease|Vaso-occlusive Crisis|Acute Chest Syndrome
Interventions: DRUG: A-001|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Test a Medicine (Fitusiran) for Preventing Bleeds in People With Severe Hemophilia Who Previously Received Preventive Treatment With Emicizumab
Status: RECRUITING
Conditions: Hemophilia A
Interventions: DRUG: Fitusiran (SAR439774)|BIOLOGICAL: Clotting factor concentrates (CFC) or bypassing agents (BPA)|BIOLOGICAL: Antithrombin concentrate (ATIIIC)|BIOLOGICAL: Emicizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vatalanib and Octreotide in Treating Patients With Progressive Neuroendocrine Tumors
Status: WITHDRAWN
Conditions: Gastrointestinal Carcinoid Tumor|Islet Cell Carcinoma
Interventions: DRUG: octreotide acetate|DRUG: vatalanib|PROCEDURE: anti-cytokine therapy|PROCEDURE: antiangiogenesis therapy|PROCEDURE: biological therapy|PROCEDURE: endocrine therapy|PROCEDURE: enzyme inhibitor therapy|PROCEDURE: growth factor antagonist therapy|PROCEDURE: hormone therapy|PROCEDURE: protein tyrosine kinase inhibitor therapy|PROCEDURE: somatostatin analogue therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison Between Letrozole and Mifepristone in Medical Termination of First Trimester Miscarriages
Status: RECRUITING
Conditions: Miscarriage
Interventions: DRUG: Mifepristone|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TNFalpha and Interleukin 2 Coding Oncolytic Adenovirus TILT-123 During TIL Treatment of Advanced Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Melanoma
Interventions: BIOLOGICAL: TILT-123
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PIONEER Trial:Hemodynamic Support With ECMO and IABP in Elective Complex High-risk PCI
Status: UNKNOWN
Conditions: Coronary Artery Disease|Heart Failure
Interventions: DEVICE: extracorporeal membrane oxygenation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Midostaurin and Azacitidine in Treating Elderly Patients With Acute Myelogenous Leukemia
Status: COMPLETED
Conditions: Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: midostaurin|DRUG: azacitidine|OTHER: bone marrow aspiration|OTHER: mutation analysis|OTHER: Pharmacokinetic study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucagon-like Peptide 2 - a Glucose Dependent Glucagonotropic Hormone?
Status: COMPLETED
Conditions: Glucose Metabolism Disorders|Endocrine or Metabolic Disease
Interventions: OTHER: Glucagon-like peptide 2|OTHER: Saline|OTHER: Glucose|OTHER: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Positive Communication and Clinical Performance in Anaesthetic Care.
Status: COMPLETED
Conditions: Positive Communication|Clinical Performance|Anaesthesiology|High Fidelity Simulation
Interventions: OTHER: Positive communication during medical transmission
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of T Cells on Age-related Vascular Dysfunction: A Translational Approach
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases|Inflammation|Aging
Interventions: OTHER: Placebo|DRUG: Abatacept 10 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multihance Versus Magnevist in Breast MRI
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Multihance|DRUG: Magnevist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Volume Stable Collagen Matrix in the Regenerative Outcome of Periodontal Intrabony Defects
Status: NOT_YET_RECRUITING
Conditions: Intrabony Periodontal Defect
Interventions: PROCEDURE: TEST GROUP: VCMX + OFD, CONTROL GROUP : OFD ONLY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Symptom Burden in Head and Neck Cancer
Status: TERMINATED
Conditions: Head And Neck Cancer
Interventions: OTHER: Placebo|DRUG: Armodafinil|DRUG: Minocycline|DRUG: Bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Subsensory Sacral Nerve Stimulation for Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DEVICE: Subsensory|DEVICE: OFF|DRUG: Suprasensory
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conversion of Maintenance Prograf to Envarsus in Liver Transplant Recipients
Status: ENROLLING_BY_INVITATION
Conditions: Liver Transplant Rejection|Immune System Suppression
Interventions: DRUG: Prograf|DRUG: Envarsus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reversal of Neuromuscular Blockade and Perioperative Arrhythmias
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: DRUG: Neostigmine|DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Azacitidine With or Without Birinapant in Subjects With MDS or CMMoL
Status: TERMINATED
Conditions: Myelodysplastic Syndrome (MDS)|Chronic Myelomonocytic Leukemia (CMML)
Interventions: DRUG: birinapant|DRUG: Azacitidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Fractional Co2 Laser Either With Tacrolimus, Calcipotriol or NB-UVB in Stable Generalized Vitiligo
Status: UNKNOWN
Conditions: Vitiligo Vulgaris
Interventions: DRUG: Tacrolimus ointment|DRUG: calcipotriol ointment|DRUG: NB-UVB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phosphatidylinositol 3 Kinase and Mammalian Target of Rapamycin (PI3K-mTOR) in Advanced Cancer Patients
Status: TERMINATED
Conditions: Advanced Cancers
Interventions: DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Viome Nutritional Programs to Improve Clinical Outcomes for Metabolic Conditions
Status: RECRUITING
Conditions: Metabolic Health
Interventions: COMBINATION_PRODUCT: VIOME Precision Nutrition Program|DIETARY_SUPPLEMENT: VIOME-designed condition-based supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Intervention for Sleep Disturbance and Symptom Management in Hematologic Cancer Patients During and After Inpatient Treatment
Status: NOT_YET_RECRUITING
Conditions: Hematologic Malignancy
Interventions: BEHAVIORAL: Nite2Day+
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Efficacy of FF-10832 in Combo With Pembrolizumab in Urothelial & Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Advanced Urothelial Carcinoma|Advanced Non Small Cell Lung Cancer
Interventions: DRUG: Pembrolizumab|DRUG: FF-10832
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prone or Supine Effect After Caesarean Delivery on Respiratory Outcomes in Full Term Infants
Status: COMPLETED
Conditions: Prone vs Supine Effects on Respiratory Outcomes
Interventions: OTHER: positioning|OTHER: positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial Monitoring Therapy Pathways of Asthma Patients Treated With an Extrafine ICS/LABA/LAMA Single-inhaler Triple Therapy in a Real-world Setting and Characterizing the Effects on Health-related Out-comes
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: Non-interventional
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vaginal Progesterone Versus Progesterone in Oil in Donor Egg Recipient In Vitro Fertilization Cycles Utilizing Vitrified Donor Eggs
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Endometrin|DRUG: Progesterone in Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does the Degree of Cervical Stenosis Affect Proprioception?
Status: NOT_YET_RECRUITING
Conditions: Proprioceptive Disorders|Stenosis
Interventions: OTHER: Pain|OTHER: Normal Range of Motion|OTHER: Proprioceptive Sense
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Totalfil and Neosealer Sealers on the Post-endodontic Pain
Status: RECRUITING
Conditions: Irreversible Pulpitis
Interventions: PROCEDURE: Totalfil|PROCEDURE: NeoSealer|PROCEDURE: AH-Plus sealer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Anti-Diabetic and Cholesterol-Lowering Effects of Cinnamon and Cassia Bark
Status: UNKNOWN
Conditions: Type 2 Diabetes|Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Cinnamonforce|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: M7824 (MSB0011359C) in Combination With Gemcitabine in Adults With Previously Treated Advanced Adenocarcinoma of the Pancreas
Status: TERMINATED
Conditions: Cancer of Pancreas|Pancreas Cancer|Pancreatic Adenocarcinoma|Pancreatic Cancer|Pancreatic Neoplasms
Interventions: DRUG: M7824|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VX-950-TiDP24-C132: A Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics of Telaprevir.
Status: COMPLETED
Conditions: Hepatitis C|Kidney Diseases
Interventions: DRUG: telaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Core Stability Versus Swiss Ball Exercise in Patients With Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Core stability exercises along with conventional physical therapy|OTHER: Swiss ball exercises along with the conventional physical therapy protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exoskeletal-Assisted Walking in SCI Acute Inpatient Rehabilitation
Status: COMPLETED
Conditions: Spinal Cord Injuries|Inpatient
Interventions: DEVICE: Ekso™ powered exoskeleton|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Advanced Cancer
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: alvocidib|DRUG: leucovorin calcium|DRUG: fluorouracil|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Internet-based Dialectical Behaviour Therapy-informed Skills Training for Reducing Alcohol Consumption and Improving Psychological Distress of Adult Smokers.
Status: NOT_YET_RECRUITING
Conditions: Smoking
Interventions: BEHAVIORAL: Internet-based dialectical behaviour therapy-informed skills training|BEHAVIORAL: Monthly health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: High Flow Nasal Cannula and Exercise Testing in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: COPD
Interventions: DEVICE: High Flow Nasal Cannula Oxygen|DEVICE: Treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Apatinib Combined With Temozolomide in the Treatment of Uncontrolled or Repeated High-grade Gliomas
Status: UNKNOWN
Conditions: High-grade Gliomas
Interventions: DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychiatric Disorders Related to Diabetes Mellitus Type 1 Among Children in Egypt
Status: UNKNOWN
Conditions: Diabetes Mellitus Type 1|Adolescents|Psychiatric Disorders
Interventions: BEHAVIORAL: The Strengths and Difficulties Questionnaire (SDQ) Parent Version Parent : It consists of 25 questionnaires used to screen for behavioral problems in children aged 4-17 years.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Postoperative Exercise Training in Patients With Colorectal Liver Metastases Undergoing Surgery (ELMA)
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Liver Metastasis
Interventions: BEHAVIORAL: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of 131I-TM-601 to Treat Adult Patients With Recurrent Glioma.
Status: COMPLETED
Conditions: Glioma|Brain Neoplasm
Interventions: DRUG: 131I-TM-601
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peer-supporting for Teenagers With Cystic Fibrosis in the Transition of Care From Paediatric to Adult Services
Status: NOT_YET_RECRUITING
Conditions: Cystic Fibrosis
Interventions: OTHER: Peer support program (intervention phase)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Interaction Between Tramadol and Ondansetron
Status: COMPLETED
Conditions: Cholecystectomy, Laparoscopic
Interventions: DRUG: Ondansetron 4 MG (Kemoset 4mg)|OTHER: Salin solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dynamic Assessment and Referral System - Evaluation
Status: COMPLETED
Conditions: Smoking|Alcohol Abuse|Drug Abuse
Interventions: BEHAVIORAL: Self-administered computerized assessment for tobacco, substance abuse, and alcohol use.|BEHAVIORAL: Self-Administered Computerized Assessment and Counseling for Tobacco, Alcohol, and Substance Abuse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of the lOw IGF-1 Syndrome aSsociated With Chronic Heart fAilure: A Randomized, Placebo-Controlled, Double-Blind Study.
Status: SUSPENDED
Conditions: Chronic Heart Failure
Interventions: DRUG: Growth Hormone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Concordance Study Comparing Insulin Treatments in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Human Insulin Inhalation Powder|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GA-68 DOTA-TOC of Somatostatin Positive Malignancies
Status: TERMINATED
Conditions: Neuroendocrine Tumor|Paraganglioma|Carcinoid Tumors|Neuroblastoma
Interventions: PROCEDURE: Computed Tomography (CT)|DRUG: Gallium Ga 68-Edotreotide|PROCEDURE: Magnetic Resonance Imaging (MRI)|PROCEDURE: Positron Emission Tomography (PET)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ProF-001_Phase IIa
Status: COMPLETED
Conditions: Vulvovaginal Candidiasis (VVC)
Interventions: DRUG: Candiplus|DRUG: Clotrimazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Microbiome on Immune Checkpoint Inhibitor Response in Melanoma Patients
Status: COMPLETED
Conditions: Clinical Stage IV Cutaneous Melanoma AJCC v8|Pathologic Stage IV Cutaneous Melanoma AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|OTHER: Laboratory Biomarker Analysis|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Induction to Labour With Double Cervical Ballon at Home Versus at Hospital
Status: RECRUITING
Conditions: Induced; Birth|Cervical Dilatation|Live Birth
Interventions: DEVICE: Cervical rippening at home|DEVICE: Cervical rippening in the hospital
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heart Catheterization Using Magnetic Resonance Imaging (MRI) Fluoroscopy and Passive Guidewires
Status: RECRUITING
Conditions: Pulmonary Artery Hypertension|Congenital Heart Disease|Structural Heart Disease
Interventions: PROCEDURE: MRI Heart guidewire catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Epirubicin Hydrochloride, Cisplatin, and Fluorouracil or Capecitabine With or Without Lapatinib Ditosylate as First-Line Therapy in Treating Patients With Stomach Cancer or Gastroesophageal Junction Cancer
Status: TERMINATED
Conditions: Adenocarcinoma of the Gastroesophageal Junction|Gastric Cancer
Interventions: DRUG: capecitabine|DRUG: cisplatin|DRUG: epirubicin hydrochloride|DRUG: fluorouracil|DRUG: lapatinib ditosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CD19-Car T Cell Therapy for the Treatment of Older Adults With Acute Lymphoblastic Leukemia in First Remission
Status: RECRUITING
Conditions: B Acute Lymphoblastic Leukemia
Interventions: DRUG: Autologous Anti-CD19 CAR-expressing T Lymphocytes|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration and Biopsy|DRUG: Cyclophosphamide|DRUG: Fludarabine|PROCEDURE: Leukapheresis|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Bone Changes After Immediate Implant Placement or Socket Preservation With or Without Surgical Flap in The Aesthetic Zone
Status: COMPLETED
Conditions: Alveolar Socket Preservation
Interventions: DRUG: Alveolar socket preservation with graft and flap surgery|DEVICE: Immediate implant placement with bone using flapless surgery|DEVICE: Immediate implant placement with bone using flap surgery|DRUG: Alveolar socket preservation with graft and flapless surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Continuous Epidural Analgesia and Continuous Intravenous Analgesia on Postoperative Bowel Movement in Patients Undergoing Laparoscopic Gastrectomy
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: OTHER: continuous epidural analgesia|OTHER: continuous intravenous analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Predictors for Venous Thromboembolism in Patients With a History of Thrombosis (PREDICTORS)
Status: COMPLETED
Conditions: Thromboembolic Disease Recurrent|Deep Vein Thrombosis|Pulmonary Embolism|Venous Thromboembolism|Recurrent Thromboembolic Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Screening for Acute Malnutrition
Status: NOT_YET_RECRUITING
Conditions: Acute Malnutrition in Childhood
Interventions: OTHER: Caretaker MUAC screening - training by health workers|OTHER: Caretaker MUAC screening - training by caregivers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Seretide Versus Flixotide In Asthmatic Children Not Controlled By Inhaled Corticosteroids
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone propionate|DRUG: Fluticasone propionate/salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Extension Study to Learn About the Long-Term Safety of Fazirsiran and if Fazirsiran Can Help People With Alpha-1 Antitrypsin Liver Disease
Status: ENROLLING_BY_INVITATION
Conditions: Alpha1-Antitrypsin Deficiency
Interventions: DRUG: Fazirsiran Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Gantenerumab in Participants With Early Alzheimer's Disease (AD)
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DRUG: Gantenerumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Clesrovimab (MK-1654) in Infants (MK-1654-004)
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infection
Interventions: BIOLOGICAL: Clesrovimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Fluorouracil With or Without Eniluracil in Treating Patients With Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Colon|Adenocarcinoma of the Rectum|Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IV Colon Cancer|Stage IV Rectal Cancer
Interventions: DRUG: fluorouracil|DRUG: eniluracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Gatifloxacin in Patients With Bacterial Conjunctivitis
Status: COMPLETED
Conditions: Bacterial Conjunctivitis
Interventions: DRUG: Gatifloxacin 0.5% eye drops|DRUG: placebo eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Motivating Quitline Use Among Smokers in Treatment for Substance Use Disorders
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Brief Computer Motivational Interviewing for Smoking Cessation|BEHAVIORAL: Nutrition Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Medico-economic Comparison of Postpartum Hemorrhage Management Using the Bakri Balloon and Standard Care
Status: TERMINATED
Conditions: Postpartum Hemorrhage
Interventions: PROCEDURE: Routine care|DEVICE: Bakri balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Patient Education and Duloxetine, Alone and in Combination, for Patients With Multisystem Functional Somatic Disorder
Status: RECRUITING
Conditions: Functional Disorder
Interventions: BEHAVIORAL: Patient Education|DRUG: Duloxetine|DRUG: Benztropine Mesylate 0.5 MG and passive placebo RAP|BEHAVIORAL: Enhanced usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carvedilol (25 mg) in 24 Fed, Healthy, Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Carvedilol 25 mg tablets|DRUG: COREG® 25 mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Single Ascending-Dose Study to Characterize the Safety, Pharmacokinetics, and Pharmacodynamics of CEP-37251 in Healthy Postmenopausal Women
Status: TERMINATED
Conditions: Bone Loss|Osteoporosis
Interventions: DRUG: CEP-37251|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Taurine Supplementation on Cognitive Function in Patients With Diabetes
Status: UNKNOWN
Conditions: Taurine|Cognitive Decline|Diabetes Mellitus
Interventions: DRUG: Taurine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hybrid Course Assessment and Evaluation
Status: NOT_YET_RECRUITING
Conditions: Education, Medical
Interventions: OTHER: Hybrid course on medical thesis for post graduates general practice students|OTHER: Face-to-face teaching on medical thesis for post graduates general practice students
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Elective vs Therapeutic Neck Dissection in Treatment of Patients With Clinical T1/2N1M0 Oral Squamous Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Oral Squamous Cell Carcinoma|Neck Dissection
Interventions: PROCEDURE: Elective neck dissection|PROCEDURE: Therapeutic neck dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: USPIO-enhanced and Diffusion-weighted MRI for the Detection of Pelvic Lymph Node Metastases
Status: COMPLETED
Conditions: Prostate Cancer|Bladder Cancer
Interventions: OTHER: Imaging: diffusion-weighted MRI|OTHER: Sinerem (USPIO) enhanced MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: NPPV on Inflammatory Markers and Sleep in Severe Obese Patients With Metabolic Syndrome Undergone to Bariatric Surgery
Status: UNKNOWN
Conditions: Metabolic Syndrome
Interventions: DEVICE: Noninvasive positive airway pressure flow generator device|PROCEDURE: Bariatric Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Avelumab and/or Radiation Therapy in People With Advanced Merkel Cell Carcinoma
Status: RECRUITING
Conditions: Merkel Cell Carcinoma
Interventions: DRUG: Avelumab|RADIATION: Comprehensive Ablative Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Community-based Family Holistic Health Promotion Project in Hong Kong: A Cluster Randomized Controlled Trial (cRCT)
Status: UNKNOWN
Conditions: Family|Well-being|Physical Activity|Healthy Diet
Interventions: BEHAVIORAL: PA1: Education sessions, Reminders, Whataps group|BEHAVIORAL: PA2: Education sessions, Reminders|BEHAVIORAL: PA3: Education sessions, Whataps group|BEHAVIORAL: PA4: Education sessions|BEHAVIORAL: HD1: Education sessions, Reminders, Whataps group|BEHAVIORAL: HD2: Education sessions, Reminders|BEHAVIORAL: HD3:Education sessions, Whataps group|BEHAVIORAL: HD4: Education sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intermittent Mechanical Compression For Peripheral Arterial Disease
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Intermittent Mechanical Compression|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pediatric Kidney Transplant Study of Sirolimus, Mycophenolate Mofetil, and Corticosteroids vs Calcineurin Inhibitor Based Immunosuppression
Status: COMPLETED
Conditions: Renal Transplant
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Golimumab in Participants With Active Psoriatic Arthritis
Status: COMPLETED
Conditions: Arthritis, Psoriatic
Interventions: DRUG: Placebo|DRUG: Golimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Risk of Acute Liver Injury in Users of Antimicrobials
Status: COMPLETED
Conditions: Drug-Induced Liver Injury
Interventions: DRUG: Moxifloxacin (Avelox, BAY12-8039)|DRUG: Amoxicillin, Amoxicillin plus clavulanic acid, Cefuroxime, Clarithromycin, Doxycycline, Levofloxacin, Telithromycin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Narcolepsy Nightmare Study
Status: COMPLETED
Conditions: Narcolepsy|Narcolepsy Type 1|Narcolepsy With Cataplexy|Narcolepsy Type 2|Narcolepsy Without Cataplexy
Interventions: BEHAVIORAL: Imagery rehearsal therapy|BEHAVIORAL: Targeted dream control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concentrated Growth Factors Applied in Maxillary Sinus Floor Elevation Via a Lateral Window Approach
Status: UNKNOWN
Conditions: Maxillary Sinus Disease
Interventions: OTHER: concentrated growth factors|OTHER: hydroxyapatite and autogenous bone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PHASE III TRIAL COMPARING, NEOADJUVANT CHEMOTHERAPY FOLLOWED BY STANDARD RADIOTHERAPY VERSUS THE SAME NEOADJUVANT CHEMOTHERAPY FOLLOWED BY STANDARD RADIOTHERAPY ASSOCIATED WITH DAILY HYDROXYUREA IN THE TREATMENT OF LOCALLY ADVANCED UNDIFFERENTIATED CARCINOMA NASOPHARYNGEAL TYPE.
Status: UNKNOWN
Conditions: LOCALLY ADVANCED UNDIFFERENTIATED CARCINOMA NASOPHARYNGEAL TYPE UCNT
Interventions: DRUG: Hydroxyurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Computer Application in Improving Pulmonary Artery Catheter Waveform Interpretation
Status: TERMINATED
Conditions: Pulmonary Artery Catheter Waveform Interpretation
Interventions: DEVICE: Web-based waveform interpretation guide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Nefopam vs Tramadol in the Prevention of Post Anaesthetic Shivering
Status: UNKNOWN
Conditions: Post Anaesthetic Shivering
Interventions: DRUG: Nefopam|DRUG: Tramadol|DRUG: Metoclopramide|DRUG: Ranitidine|DRUG: Pethidine|DRUG: Ephedrine|DRUG: oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of Internet-Delivered Psychological Treatment for Cancer Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer Survivors|Anxiety|Depression
Interventions: BEHAVIORAL: Support and information|BEHAVIORAL: Behavioral activation|BEHAVIORAL: Systematic exposure with mindfulness training|BEHAVIORAL: Promotion of health behaviors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Liposomal Doxorubicin in Women With Breast Cancer Exploiting Tissue Doppler Imaging
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: liposomal doxorubicin|DRUG: epirubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Delafloxacin to Moxifloxacin for the Treatment of Adults With Community-acquired Bacterial Pneumonia
Status: COMPLETED
Conditions: Community Acquired Bacterial Pneumonia
Interventions: DRUG: Delafloxacin|DRUG: Moxifloxacin|DRUG: Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Onlay Restorations After Cervical Margin Relocation (CMR)
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Caries
Interventions: PROCEDURE: Highly viscous glass ionomer (cervical margin relocation)|PROCEDURE: Low shrinkage Flowable Composite (cervical margin relocation)|PROCEDURE: Resin Modified Glass Ionomer (cervical margin relocation)|PROCEDURE: Bioactive Ionic Resin (cervical margin relocation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Treatment of Osteoporosis Using a Combination of Teriparatide (Forteo) and Denosumab
Status: UNKNOWN
Conditions: Osteoporosis
Interventions: DRUG: Standard Clinical Practice Regimen|DRUG: Experimental Cyclic Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Skin Creams on TEWL
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: EpiCeram|DRUG: Aveeno Daily Moisturising Sheer Hydration Lotion®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Low Fat Milk Product on Lipids Profile in Dyslipidemia Subjects
Status: COMPLETED
Conditions: Primary Dyslipidemia
Interventions: DIETARY_SUPPLEMENT: sterols and hawthorn powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IVIg for Small Fiber Neuropathy With Autoantibodies TS-HDS and FGFR3
Status: COMPLETED
Conditions: Small Fiber Neuropathy|Idiopathic Peripheral Neuropathy
Interventions: DRUG: Intravenous immunoglobulin|DRUG: 0.9% Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing of a Tool to Elicit Patient Preferences for CTS
Status: COMPLETED
Conditions: Carpal Tunnel|Carpal Tunnel Syndrome|Carpal Tunnel Syndrome Left|Carpal Tunnel Syndrome Right|Carpal Tunnel Syndrome Bilateral
Interventions: OTHER: Preference Elicitation tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: INTEnsity of ovariaN Stimulation and Embryo Quality
Status: RECRUITING
Conditions: Infertility
Interventions: DRUG: Ovarian Stimulation with CC+rFSH|DRUG: Ovarian Stimulation with rFSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetes Autoimmunity Withdrawn in New Onset Patients (DAWN)
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 1
Interventions: BIOLOGICAL: TOL-3021|OTHER: TOL-3021 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Trial and Protocol for Remote Cognitive Training Developed for Use in a Cognitively Healthy Adult Population During the COVID-19 Pandemic
Status: COMPLETED
Conditions: Cognition Disorders in Old Age
Interventions: DEVICE: NeurotrackerX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimal Anti-EGFR Treatment of mCRC Patients With Low-Frequency RAS Mutation
Status: NOT_YET_RECRUITING
Conditions: Treatment Related Cancer
Interventions: DRUG: Panitumumab|DRUG: Irinotecan|DRUG: Folinic acid|DRUG: 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of 2 Doses of S-777469 in Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: S-777469 400 mg|DRUG: S-777469 800 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Personal Resilience Empowerment Program Study
Status: COMPLETED
Conditions: Lung Cancer|Cholangiocarcinoma|Pancreatic Cancer|Liver Cancer
Interventions: BEHAVIORAL: Personal Resilience Empowerment Program including 5 sessions with health coaches
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety Profile of Primary Dose of bOPV Bio Farma Given Simultaneously With Pentabio And IPV
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: bOPV|BIOLOGICAL: Pentabio|BIOLOGICAL: IPV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Influence of Radial Extracorpeal Shock Wave in Hemiplegic Shoulder Patients
Status: COMPLETED
Conditions: Hemiplegia|Spastic
Interventions: DEVICE: radial extracorpeal shock wave
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block and Thoracal Paravertebral Block Following Video Assisted Thoracic Surgery
Status: COMPLETED
Conditions: Lung Diseases
Interventions: OTHER: Erector spinae plane block (Group ESPB)|OTHER: Thoracal paravertebral block (Group TPVB)|OTHER: Control group (group C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Axial- and Lateral-viewing Capsule Endoscopy in Celiac Disease
Status: UNKNOWN
Conditions: Celiac Disease
Interventions: DEVICE: Lateral-viewing CapsoCam device|DEVICE: Axial-viewing capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate Efficacy and Safety of MELT-300 for Procedural Sedation in Subjects Undergoing Cataract Extraction With Lens Replacement (CELR)
Status: RECRUITING
Conditions: Cataract
Interventions: DRUG: MELT-300 sublingual tablet|DRUG: Midalozam sublingual tablet|DRUG: Placebo sublingual tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examining Distinct Immunophenotypes to Validate and Enhance Rational Treatment in Systemic Lupus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Mycophenolate Mofetil|DRUG: Placebo for Mycophenolate Mofetil|DRUG: Voclosporin|DRUG: Placebo for Voclosporin|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanism of Fatty Acid-Induced Impairment of Glucose-Stimulated Insulin Secretion
Status: COMPLETED
Conditions: Insulin Resistance Syndrome X|Pancreatic Beta Cell Function
Interventions: DRUG: N-acetylcysteine, intralipid, heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lenalidomide Combined to Azacitidine in Intermediate-2 or High Risk MDS With Del 5q
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Azacitidine combined to Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Explicit, Implicit and no Values Clarification Decision Aids for Men Considering Prostate Cancer Screening
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: OTHER: Decision aid with implicit values clarification method (booklet or website)|OTHER: Decision aid with explicit values clarification method (booklet or website)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A 3 Day In-use Assessment of the Scholl Corn Foam Cushions on Pain Levels Associated With Heloma Durum.
Status: COMPLETED
Conditions: Heloma Durum
Interventions: DEVICE: Corn Foam Cushion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Intravenous Ondansetron in the Prevention of Spinal Anaesthesia-induced Hypotension in Caesarean Section
Status: TERMINATED
Conditions: Hypotension
Interventions: PROCEDURE: Spinal anaesthesia|DRUG: Ondansetron|OTHER: saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Gabapentin and Oxcarbazepine for Chronic Neuropathic Pain in Children and Adolescents: A Clinical Effectiveness Study
Status: NOT_YET_RECRUITING
Conditions: Pediatric Chronic Neuropathic Pain
Interventions: DRUG: Gabapentin|DRUG: Oxcarbazepine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT