pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pilot Trial of "Chemo-Switch" Regimen to Treat Advanced Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: Concurrent decrescendo biochemotherapy regimen|DRUG: Low-dose Temozolomide plus Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Women Empowered to Live With Lupus Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Lupus Erythematosus, Systemic
Interventions: BEHAVIORAL: Chronic Disease Self-Management Program (CDSMP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RAD001 (Everolimus) + Docetaxel + Cisplatin as Induction Chemotherapy in Patients With Local-Regional Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: HEAD & NECK Cancer
Interventions: DRUG: RAD001 + docetaxel + cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determine the Efficacy and Safety of Harvoni in Genotype 1 Chronic Hepatitis c Infected People Who Are Alcoholics
Status: COMPLETED
Conditions: Genotype 1 Hepatitis C Virus
Interventions: DRUG: harvoni
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two Dimensional (2D) Silicon Transducer-Compression Plates for Breast Ultrasound
Status: COMPLETED
Conditions: Breast Tumor|Breast Cysts
Interventions: PROCEDURE: Experimental 3D Breast Ultrasound imaging|PROCEDURE: Experimental Photoacoustic Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of N-acetylcysteine in Patients With COVID-19 Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Covid-19
Interventions: DRUG: N-acetylcysteine|OTHER: Peripheral Blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Linagliptin (BI 1356) Plus Metformin in Type 2 Diabetes, Factorial Design
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: BI 1356|DRUG: BI 1356 + metformin|DRUG: Bi 1356 + metformin|DRUG: Metformin|DRUG: metformin|DRUG: matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Switch Study: The Role of Lamivudine/Emtricitabine (3TC/FTC) in Antiretroviral Regimens
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: 3TC and FTC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Aminolevulinic Acid (ALA) to Enhance Visualization and Resection of Tumors of the Brain
Status: TERMINATED
Conditions: Glioma
Interventions: DRUG: 5-Aminolevuline Acid (ALA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mental Health in Dancers; an Intervention Study
Status: COMPLETED
Conditions: Mental Health Impairment|Mental Health|Eating Disorders|Perfectionism|Depression, Anxiety|Coping Behavior|Self Esteem|Body Image|Body Weight
Interventions: BEHAVIORAL: Mental health literacy in dancers|BEHAVIORAL: Mental health literacy in dance teachers
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Association of Intraoperative Haemodynamic and Postoperative Complications in Type A Aortic Dissection Surgery
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: OTHER: Primary exposures were venous congestion defined by central venous pressure (CVP) and mean arterial pressure (MAP).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment of Post-Stroke Spasticity
Status: COMPLETED
Conditions: Spasticity
Interventions: DEVICE: repetitive Transcranial Magnetic Stimulation (rTMS)|DEVICE: Sham repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot PK/PD Study of DS-1093a in Patients With Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Renal Disease|Renal Anemia
Interventions: DRUG: DS-1093a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Antibiotics in Chronic Obstructive Pulmonary Disease (COPD)
Status: WITHDRAWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Doxycycline|DRUG: Placebo (matching)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Treatment of Cervical Intraepithelial Lesions With Imiquimod or LLETZ
Status: UNKNOWN
Conditions: Intraepithelial Neoplasia, Cervical
Interventions: DRUG: Aldara 5% Topical Cream|PROCEDURE: LLETZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A PD/Safety Study of RDEA3170 in Combination With Febuxostat for Treating Gout or Asymptomatic Hyperuricemia Patients
Status: COMPLETED
Conditions: Gout and Asymptomatic Hyperuricemia
Interventions: DRUG: RDEA3170|DRUG: Febuxostat|DRUG: Benzbromarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Operative vs. Conservative Treatment of Distal Radius Fractures
Status: COMPLETED
Conditions: Radius Distal Fracture|Distal Radius Fracture|Radius Fracture Distal
Interventions: PROCEDURE: ORIF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Avelumab in Metastatic or Locally Advanced Solid Tumors (JAVELIN Solid Tumor JPN)
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Avelumab 3 mg/kg|DRUG: Avelumab 10 mg/kg|DRUG: Avelumab 20 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Struggle That Is Phenylketonuria : What Do The Patients and Caregivers Suffer From
Status: COMPLETED
Conditions: Psychological Well-Being|Caregiver Burden|Life Stress
Interventions: OTHER: parenting stress index, Zarit burden scale, Rosenberg self esteem scale, stait trait anxiety inventory, struggles and difficulties questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Glucagon-like Peptide-1 Levels, Insulin Resistance and Insulin Sensitivity Index in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|PreDiabetes
Interventions: DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Dose-escalation Study to Evaluate the Safety, Tolerability, and Antitumor Activity of MEDI-573 in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: MEDI-573
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Activity in Patients With Homologous Recombination Competent and Deficient Tumors
Status: COMPLETED
Conditions: Solid Tumor, Adult
Interventions: DRUG: Pembrolizumab 200 mg Q3W
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Amoxicillin 400 mg/Clavulanic Acid 57 mg Chewable Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: amoxicillin 400mg + clovalunic acid 57.5mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Topical Steroid Treatment for Eosinophilic Esophagitis
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: Fluticasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of MK0476 in the Treatment of Asthma Patients Aged 2-5 Years (0476-907)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: montelukast|DRUG: placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Medication Management Service
Status: RECRUITING
Conditions: Medication Adherence|Medication Safety|Diabetes Mellitus, Type 2|Hypertension|Polypharmacy|High Risk Medications
Interventions: BEHAVIORAL: Medication Management Service (MMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety in a Randomised Acute Pain Study of MR308 (Tramadol/Celecoxib).
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: MR308|DRUG: Tramadol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intrapartum Non-invasive Electrophysiological Monitoring
Status: RECRUITING
Conditions: Fetal Monitoring|Non-invasive|Cardiotocography|Electrocardiography|Caesarean Section
Interventions: DEVICE: eCTG monitoring with the NFMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Long-term Access Program (LAP) of Mepolizumab for Subjects Who Participated in Study MEA115921
Status: COMPLETED
Conditions: Churg-Strauss Syndrome|Eosinophilic Granulomatosis With Polyangiitis
Interventions: DRUG: Mepolizumab|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the DPP-4 Inhibitor Sitagliptin on Islet Function After Mixed Meal in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose:
Clinical trial: The Effect of Myo-inositol, Somatropin, and DHEA on Poor Ovarian Responders
Status: NOT_YET_RECRUITING
Conditions: Poor Responders
Interventions: DRUG: myo-inositol|DRUG: Somatropin|DRUG: Dehydroepiandrosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Immunodeficiency Virus (HIV) Food Insecurities
Status: RECRUITING
Conditions: Food Insecurities|Cardiometabolic Comorbidities|HIV|PreDiabetes|Type 2 Diabetes Mellitus (T2DM)
Interventions: BEHAVIORAL: weCare/Secure|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study on the Effect of Capacity Shock Intervention Under Goal-directed Hemodynamic Management on P-V Loop
Status: COMPLETED
Conditions: Hemodynamics
Interventions: PROCEDURE: Fluid challenge strategy|PROCEDURE: conventional strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Benazir Nashonuma Program (BNP) on Maternal and Child Nutritional Status
Status: RECRUITING
Conditions: Low Birthweight|Stunting|Wasting|Malnutrition, Child|Iron Deficiency Anemia|Dietary Habits
Interventions: OTHER: Benazir Nashonuma Program (BNP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of Cefixime Trihydrate Dry Syrup in Indonesia Healthy Volunteers
Status: COMPLETED
Conditions: Drug Use
Interventions: DRUG: Cefixime Trihydrate 100 mg/5 mL Dry Syrup|DRUG: Suprax 100 MG in 5 mL Oral Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect Of Baby Smell On The Amount Of Breast Milk, Salivary Cortisol Level And Mother Baby Attachment
Status: NOT_YET_RECRUITING
Conditions: Mother-Infant Interaction|Premature Birth
Interventions: BEHAVIORAL: Baby smell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Biweekly Schedule of Docetaxel and Cisplatin in High Risk Patients With Unresectable Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Docetaxel and Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab and Bevacizumab in Patients With Recurrent or Metastatic Squamous-cell Carcinoma of the Head and Neck
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Neoplasms
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Infertility in Women With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Infertility|Pregnancy
Interventions: DRUG: metformin XR|DRUG: clomiphene citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of a New Eyedrop on Silicone Hydrogel Contact Lens Wearers With Dry Eye Complaints
Status: COMPLETED
Conditions: Contact Lens Related Dry Eye Syndrome
Interventions: DEVICE: OPTIVEtm Plus|PROCEDURE: No treatment|DEVICE: Blink Contacts® Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study to Evaluate Safety & Benefit of Eclipse XL1 System in Adult Patients With SBS
Status: RECRUITING
Conditions: Short Bowel Syndrome
Interventions: DEVICE: Distraction Enterogenesis in Adult Patients with Short Bowel Syndrome
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Postoperative Pain After Mastectomy
Status: ENROLLING_BY_INVITATION
Conditions: Mastectomy; Lymphedema
Interventions: DEVICE: Cryoneurolysis|DEVICE: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study of Entinostat and Exemestane in Postmenopausal Women With ER+ Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Estrogen Receptor Positive Breast Cancer
Interventions: DRUG: entinostat|DRUG: exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Status and Dose Response in Infants
Status: COMPLETED
Conditions: Vitamin D|Prematurity
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: vitamin D3 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: U.S. Multicenter Feasibility Trial of the F2 Filter and Delivery System for Embolic Protection During TAVR
Status: NOT_YET_RECRUITING
Conditions: Aortic Stenosis
Interventions: DEVICE: Aortic Stenosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of SK3530 on Erectile Dysfunction in Patients With Diabetes Mellitus
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Placebo|DRUG: SK3530
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab in Combination With Chemotherapy for Conversion Therapy of Locally Nonresectable ESCC
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma|Locally Advanced Carcinoma
Interventions: DRUG: Tislelizumab|DRUG: 5-FU|DRUG: cis Platinum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal LSTA1 in CRS-HIPEC
Status: WITHDRAWN
Conditions: Colorectal Cancer|Ovarian Carcinoma|Appendix Cancer|Peritoneal Metastases
Interventions: DRUG: CRS-HIPEC + LSTA1|PROCEDURE: CRS-HIPEC alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab (MK-3475) and Pembrolizumab With Other Investigational Agents in Participants With High Risk Non-muscle Invasive Bladder Cancer (MK-3475-057/KEYNOTE-057)
Status: RECRUITING
Conditions: Bladder Cancer
Interventions: BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Pembrolizumab/vibostolimab coformulation|BIOLOGICAL: Favezelimab/pembrolizumab coformulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between Saliva β-endorphins Levels, Cold Pressor Test and Perception of Pain in Oral Surgery Procedures
Status: UNKNOWN
Conditions: Hyperalgesia|Pain Insensitivity, Congenital
Interventions: DEVICE: Cold pressor test|OTHER: β-endorphins evaluation in saliva|OTHER: β-endorphins evaluation in blood plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Analysis of Human Movement With Assistive Devices
Status: RECRUITING
Conditions: Limb Loss|Limb Weakness|Limb Paralysis|Movement Disorders
Interventions: DEVICE: Assist-Knee|DEVICE: Prosthetic Knee|DEVICE: Prosthetic Ankle|DEVICE: Prosthetic Foot|DEVICE: Ankle-Foot Orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Conical Forearm and Cylindrical Upper Arm Non-Invasive Blood Pressure (NIBP) Measurements in Pregnant Patients
Status: NOT_YET_RECRUITING
Conditions: Hypertension in Pregnancy|Hypertension|Obesity
Interventions: DEVICE: Upper Arm Cylindrical Blood Pressure Cuff|DEVICE: Forearm Conical Blood Pressure Cuff
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Effectiveness of JUVÉDERM™ Injectable Gel With Lidocaine
Status: COMPLETED
Conditions: Nasolabial Folds
Interventions: DEVICE: JUVÉDERM™ Injectable Gel with Lidocaine|DEVICE: JUVÉDERM™ Injectable Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Non-linear Frequency Compared to Conventional Processing in Patients With and Without Cochlear Dead Regions.
Status: COMPLETED
Conditions: Sensorineural Hearing Loss, Bilateral|Cochlear Hearing Loss
Interventions: DEVICE: Hearing aids programmed conventionally.|DEVICE: Hearing aids programmed with compression activated.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Intervention for Female Breast CANcer: Acceptance and Commitment Therapy (I-CAN-ACT) for Depression and Physical Pain
Status: RECRUITING
Conditions: Female Breast Cancer|Depression|Pain
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy|OTHER: Waitlist Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Dexmedetomidine in Prevention of Postoperative Delirium
Status: COMPLETED
Conditions: Delirium in Old Age|Anesthesia; Adverse Effect
Interventions: DRUG: Dexmedetomidine injection|DRUG: Sufentanil injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intra-articular Platelet Rich Plasma vs Corticosteroid in Treatment of Knee Osteoarthritis Patients
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis Knee|Corticosteroid|Platelet Rich Plasma
Interventions: DRUG: Corticosteroid|OTHER: Platelet Rich Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Post-Op Pain After Sacrospinous Ligament Colpopexy
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Bupivacaine|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How Well a Monitoring System Called Continuous Glucose Monitoring (CGM) Which Measures Glucose on an Ongoing Basis Works and How Safe it is in Chinese Patients in Usual Practice
Status: COMPLETED
Conditions: Continuous Glucose Monitoring|Diabetes Mellitus
Interventions: DEVICE: CGM System|PROCEDURE: Standard Venous Blood Glucose Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety Study of CA330 Hemoadsorption Device on IL-6 Removal in Septic Patients
Status: UNKNOWN
Conditions: Sepsis
Interventions: DEVICE: hemoperfusion with cytokine adsorption column (CA330)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy (CBT)|BEHAVIORAL: Waitlist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Long COVID Symptoms Utilizing Autologous Stem Cells Following COVID-19 Infection
Status: NOT_YET_RECRUITING
Conditions: Long COVID
Interventions: PROCEDURE: Adipose Tissue Harvest|BIOLOGICAL: ATCell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Energy Imbalance on Food Intake Behaviors
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Eucaloric Feeding Period|OTHER: Overfeeding Feeding Period|OTHER: Underfeeding Feeding Period
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Erinacine A-enriched Hericium Erinaceus Mycelia for Improvement of Recognition, Vision, and Functional MRI Alterations
Status: COMPLETED
Conditions: Supplement|Cognition Disorders in Old Age|Vision|fMRI
Interventions: DIETARY_SUPPLEMENT: Erinacine A-enriched Hericium Erinaceus Mycelia|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Weekly Docetaxel and Fixed-Dose Rate Gemcitabine Combination Chemotherapy
Status: UNKNOWN
Conditions: Sarcoma
Interventions: DRUG: Gemcitabine and Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rectal Cancer Anastomosis 4 Check Study
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: COMBINATION_PRODUCT: intraoperative near infrared (NIR) indocyanine green (ICG)-induced fluorescence angiography (FA) and air leak testing to assess the integrity and the perfusion levels of the colorectal anastomosis|DIAGNOSTIC_TEST: Air Leak test|DIAGNOSTIC_TEST: Evaluation of the anastomotic rings
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dexcom G6 Continuous Glucose Monitoring in Hemodialysis
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes|Hemodialysis|Glucose Measurement
Interventions: DEVICE: Dexcom G6 Continuous Glucose Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 2 Study of Maintenance OSI-906 Plus Erlotinib (Tarceva®), or Placebo Plus Erlotinib in Patients With Nonprogression Following 4 Cycles of Platinum-based Chemotherapy
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer (NSCLC) With Nonprogression Following 4 Cycles of Platinum-based Chemotherapy
Interventions: DRUG: OSI-906|DRUG: erlotinib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing and Advancing SBIRT in Schools
Status: ENROLLING_BY_INVITATION
Conditions: Adolescent Drinking|Adolescent Substance Use|Risk Behavior, Health
Interventions: BEHAVIORAL: Indicated Prevention, Clinical Staff|BEHAVIORAL: Selective Prevention|BEHAVIORAL: Expanded Paraprofessional Workforce
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Nivolumab in Patients With Head and Neck Cancer.
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma of the Head and Neck; Head and Neck Cancer; Head and Neck Carcinoma; Cancer of the Head and Neck
Interventions: BIOLOGICAL: Nivolumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Drainage of Malignant Extrinsic Ureteral Obstruction Using the Memokath Ureteral Stent
Status: COMPLETED
Conditions: Ureteral Obstruction
Interventions: DEVICE: Memokath 051 Ureteral Stent|DEVICE: JJ Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study Between Dolutegravir and an Oral Contraceptive Containing Norgestimate and Ethinylestradiol
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: Ortho-Cyclen|DRUG: Dolutegravir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Daily Aspirin Treatment After Preeclampsia
Status: RECRUITING
Conditions: Preeclampsia
Interventions: DRUG: Aspirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness and Safety of the Facet Fixation (FFX®) Implant in the Treatment of Degenerative Lumbar Spinal Stenosis
Status: NOT_YET_RECRUITING
Conditions: Degenerative Lumbar Spinal Stenosis
Interventions: DEVICE: Decompression + FFX®|PROCEDURE: Decompression alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Iodine Complex Against COVID-19 Patients
Status: UNKNOWN
Conditions: Covid19|SARS-CoV-2|Corona Virus Infection
Interventions: DRUG: Iodine Complex|DRUG: Iodine Complex|DRUG: Placebo|DRUG: Idoine Complex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAOCT: Intra CoronAry Optical Computerized Tomography in out-of Hospital Cardiac Arrest Patients
Status: TERMINATED
Conditions: Out of Hospital Cardiac Arrest
Interventions: PROCEDURE: Optical Coherence Tomography|PROCEDURE: Coronary Angiography|PROCEDURE: Per cutaneous coronary intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sedation for Upper Gastrointestinal Endoscopy in Pediatric Patients
Status: COMPLETED
Conditions: Upper Gastrointestinal Endoscopy
Interventions: DRUG: Dexmedetomidine-ketamine|DRUG: propofol-ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose:
Clinical trial: Nifedipine vs Telmisartan on Prevention of Atrial Fibrillation (AF) Recurrence in Hypertensive Patients With AF
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Nifedipine,|DRUG: Telmisartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Prospective, Open-label, Randomized Controlled, Multicenter Clinical Study of MSD-HSCT Using a TBI or TMLI Conditioning Regimen for Adult ALL
Status: NOT_YET_RECRUITING
Conditions: Acute Lymphoblastic Leukemia, Adult
Interventions: RADIATION: TBI|RADIATION: TMLI|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Characteristics and Outcomes of Pediatric COVID-19
Status: COMPLETED
Conditions: COVID-19|SARS-CoV-2 Infection|Pediatric ALL|Pneumonia, Viral|Pandemic Response
Interventions: OTHER: Exposure (not intervention) - SARS-CoV-2 infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Effective and Safe Use of Stream™ Platform
Status: NOT_YET_RECRUITING
Conditions: User-Centered Design|Anastomotic Leak|Colorectal Surgery|Artificial Intelligence
Interventions: DEVICE: Stream™ Platform
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison Between OSS and 2L PEG/Asc for Bowel Preparation of Elderly People
Status: UNKNOWN
Conditions: Colonoscopy
Interventions: DRUG: Oral sulfate solution (OSS)|DRUG: 2L PEG/Asc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Beta2-adrenergic System and Training
Status: UNKNOWN
Conditions: Healthy
Interventions: BEHAVIORAL: Training|DRUG: Formoterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of Ketamine Prior to Cardiopulmonary Bypass in Children
Status: COMPLETED
Conditions: Ventricular Septal Defect
Interventions: DRUG: saline|DRUG: ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: WIBOFA - Validation of SCT02 With ECG-App for Detection of AF
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: Investigational Device (Withings SCT02) 30 second Electrocardiogram recording|DEVICE: Reference Device (Schiller Cardiovit FT-1) 30 second Electrocardiogram recording
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomised Placebo Controlled Trial of Chronic Feeding of INuliN And Methylcellulose On Colonic fermentatioN
Status: NOT_YET_RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: methylcellulose|DIETARY_SUPPLEMENT: inulin|DIETARY_SUPPLEMENT: maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: [68Ga]Ga-Sa-DABI-4 PET Imaging of Stimulator of Interferon Gene Expression in Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Stimulator of Interferon Gene|Cancer|Positron Emission Tomography
Interventions: DRUG: [68Ga]Ga-Sa-DABI-4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CLL11: A Study of Obinutuzumab (RO5072759 [GA101]) With Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 1a)
Status: COMPLETED
Conditions: Lymphocytic Leukemia, Chronic
Interventions: DRUG: obinutuzumab|DRUG: rituximab|DRUG: chlorambucil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S1501 Carvedilol in Preventing Cardiac Toxicity in Patients With Metastatic HER-2-Positive Breast Cancer
Status: RECRUITING
Conditions: Cardiotoxicity|HER2/Neu Positive|Metastatic Malignant Neoplasm in the Brain|Recurrent Breast Carcinoma|Stage IV Breast Cancer AJCC v6 and v7
Interventions: DRUG: Carvedilol|OTHER: Laboratory Biomarker Analysis|OTHER: Patient Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BH4 Blood Levels Variations in Pre Eclamptic Women
Status: COMPLETED
Conditions: Pre Eclampsia|Eclampsia, Antepartum|HELLP Syndrome (HELLP), Unspecified Trimester|Acute Renal Failure|Abruptio Placentae; Complicating Pregnancy
Interventions: DIAGNOSTIC_TEST: BH4 blood level
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Parasternal Nerve Block Using Bupivacaine for Postoperative Analgesia in Children Undergoing Cardiac Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Bupivacaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immune Response Study of High-Dose Canarypox ALVAC-HIV Vaccine in Healthy, HIV Uninfected Adults
Status: COMPLETED
Conditions: HIV Infections|HIV Seronegativity
Interventions: BIOLOGICAL: ALVAC(2)120(B,MN)GNP (vCP1452)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effect of Anthracyclines and Cyclophosphamide on Cardiovascular Responses
Status: RECRUITING
Conditions: Cardiotoxicity|Cardiovascular Disease|Neurovascular Disorder|Endothelial Disfunction|Breast Cancer
Interventions: PROCEDURE: Physical Characteristics|PROCEDURE: Muscular Sympathetic Nervous Activity|DIAGNOSTIC_TEST: Cardiac Function|DIAGNOSTIC_TEST: Heart rate|DIAGNOSTIC_TEST: Blood pressure|DIAGNOSTIC_TEST: Blood Assessments|DIAGNOSTIC_TEST: Muscle blood flow|DIAGNOSTIC_TEST: Endothelium-dependent vascular function|DIAGNOSTIC_TEST: Vascular intima-media thickness|DIAGNOSTIC_TEST: Physical Capacity|DRUG: Anthracycline & Cyclophosphamide treatment scheme
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PIMR and Pulmonary Vascular Disease
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: OTHER: Pulmonary Index of Microcirculatory Resistance|OTHER: Right Ventricle Index of Microcirculatory Resistance|OTHER: Pulmonary artery OCT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Surgical Outcome of Vitrectomy for Myopic Traction Maculopathy in Highly Myopic Eyes
Status: COMPLETED
Conditions: Maculopathy|High Myopia|Surgery
Interventions: PROCEDURE: vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Deciphering the Role of Dietary Fatty Acids on Extracellular Vesicles-mediated Intercellular Communication
Status: NOT_YET_RECRUITING
Conditions: Obesity|Metabolic Syndrome|Metabolic Disorder|Inflammation|Immune System and Related Disorders
Interventions: DIETARY_SUPPLEMENT: Oral lipid emulsions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: MIPO Versus Conventional Approach in Volar Locking Plate for Close Fractures Distal End Radius Under WALANT
Status: COMPLETED
Conditions: Radius; Fracture, Lower or Distal End
Interventions: PROCEDURE: MIPO|PROCEDURE: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MRI and PET Imaging in Predicting Treatment Response in Patients With Stage IB-IVA Cervical Cancer
Status: TERMINATED
Conditions: Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Cervical Squamous Cell Carcinoma, Not Otherwise Specified|Cervical Undifferentiated Carcinoma|Recurrent Cervical Carcinoma|Stage IB2 Cervical Cancer|Stage II Cervical Cancer|Stage IIA Cervical Cancer|Stage IIB Cervical Cancer|Stage III Cervical Cancer|Stage IIIA Cervical Cancer|Stage IIIB Cervical Cancer|Stage IVA Cervical Cancer
Interventions: PROCEDURE: Computed Tomography|PROCEDURE: Diffusion Weighted Imaging|PROCEDURE: Dynamic Contrast-Enhanced Magnetic Resonance Imaging|RADIATION: Fludeoxyglucose F-18|PROCEDURE: Magnetic Resonance Spectroscopic Imaging|PROCEDURE: Positron Emission Tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Community Awareness Resources and Education - Project 1
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: BEHAVIORAL: Lay Health Advisor Education Intervention|BEHAVIORAL: Usual Care Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Velcade Plus ICE for Patients With Relapsed Classical Hodgkin Lymphoma
Status: COMPLETED
Conditions: Hodgkin Lymphoma|Lymphoma
Interventions: DRUG: Bortezomib|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Ifosfamide|DRUG: Mesna
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Sildenafil Citrate in Management of Mild Pre-eclampsia
Status: UNKNOWN
Conditions: Pre-Eclampsia; Mild
Interventions: DRUG: Sildenafil 20 MG|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HOPE-CVD-Virtual: A Virtual Trial to Evaluate the Primary Prevention of CVD
Status: RECRUITING
Conditions: Cardiovascular Diseases
Interventions: BEHAVIORAL: HeartAge|BEHAVIORAL: HOPE-CVD Mobile App|BEHAVIORAL: Genetic Risk Score
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Dosing of Intra-articular Triamcinolone Hexacetonide for Knee Synovitis in Chronic Polyarthritis
Status: UNKNOWN
Conditions: Arthritis of the Knee
Interventions: DRUG: Triamcinolone hexacetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Patient Tolerability and Success for Penile and Scrotal Urologic Procedures Under Conscious Sedation: A Prospective Study
Status: ENROLLING_BY_INVITATION
Conditions: Hydrocele|Spermatocele|Varicocele|Epididymal Cyst|Testicular Biopsy|Circumcision|Frenulectomy|Penile Plication|Orchiectomy|Vasectomy Reversal|Testicular Diseases|Penile Diseases
Interventions: OTHER: Conscious sedation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized, Double-blind, Placebo Controlled Study to Assess Efficacy, Safety and Tolerability of LCQ908 in Subjects With Familial Chylomicronemia Syndrome
Status: COMPLETED
Conditions: Familial Chylomicronemia Syndrome (FCS)
Interventions: DRUG: LCQ908|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Talazoparib in Combination With Gemcitabine and Cisplatin in Patients With Advanced Solid Tumors
Status: WITHDRAWN
Conditions: Solid Tumors|Carcinoma, Non-Small Cell Lung|Non-Small Cell Lung Cancer|Non-Small-Cell Lung Carcinoma|Nonsmall Cell Lung Cancer
Interventions: DRUG: Cisplatin|DRUG: Gemcitabine|DRUG: Talazoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults With Repaired or Palliated Conotruncal Cardiac Defects
Status: COMPLETED
Conditions: Hypoparathyroidism|Tetralogy of Fallot|Pulmonary Valve Stenosis|Conotruncal Cardiac Defects|Heart Defects, Congenital|Pulmonary Atresia
Interventions: DRUG: calcium gluconate|DRUG: sodium citrate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fludarabine, Pixantrone and Rituximab vs Fludarabine and Rituximab forRelapsed or Refractory Indolent NHL
Status: WITHDRAWN
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: fludarabine and rituximab|DRUG: fludarabine, rituximab, pixantrone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of Direct Aspiration First Pass Technique (ADAPT) for Thrombectomy Revascularisation of Large Vessel Occlusion in Acute Ischaemic Stroke
Status: COMPLETED
Conditions: Ischemic Cerebrovascular Accident
Interventions: PROCEDURE: direct aspiration procedure|PROCEDURE: stent retriever procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TGRX-326 Pharmacokinetic Drug Interaction
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Itraconazole+TGRX-326|DRUG: Efavirenz+TGRX-326
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetics in the Progression of Nephropathies
Status: RECRUITING
Conditions: AKI|CKD|Ckd-Mbd|CKD (Chronic Kidney Disease) Stage 5D|ADPKD|Hypertension|Hematologic Malignancy|Bone Marrow Transplant Complications
Interventions: GENETIC: genetic polymorphisms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Botulinum Toxin Efficiency on Spasticity of Rectus Femoris and Semitendinosus Muscles as Functional Agonist and Antagonist Muscles
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DRUG: Botulinum toxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aronia Berry Consumption on Vascular Function
Status: COMPLETED
Conditions: Healthy Young Men
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Aronia full spectrum|DIETARY_SUPPLEMENT: Aronia extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Empagliflozin on Liver Fat in Non-diabetic Patients
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Placebo pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plastic vs Biodegradable Pancreatic Stent in Post-ERCP Pancreatitis Prevention
Status: UNKNOWN
Conditions: Biliary Tract Diseases
Interventions: DEVICE: Pancreatic duct stenting with plastic stent|DEVICE: Pancreatic duct stenting with Biodegradable Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Efficacy and Safety of Two Intensification Strategies in Subjects With Type 2 Diabetes Inadequately Controlled on Basal Insulin and Metformin
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec|DRUG: insulin aspart|DRUG: liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Of Drospirenone and Ethinyl Estradiol vs Placebo in the Treatment of Truncal Acne
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: drospirenone and ethinyl estradiol|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Intense Aerobic Exercise on the Cerebrovascular Reserve Capacity in Patients With Hemodynamically Relevant Intra- and Extracranial Stenoses
Status: TERMINATED
Conditions: Stenosis
Interventions: BEHAVIORAL: Intense aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Efficacy, Safety and Pharmacokinetics of a Tacrolimus New Oral Formulation (MR4) in BMT Recipients
Status: COMPLETED
Conditions: Bone Marrow Transplantation|Graft Versus Host Disease|Graft-Vs-Host Disease|Graft-Versus-Host Disease
Interventions: DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Posterior Macular Adhesion: A Potential Risk Factor for Non-exudative Age Related Macular Degeneration (AMD) to Develop Exudative AMD
Status: UNKNOWN
Conditions: Dry Age-related Macular Degeneration|Detachment of the Posterior Hyaloid
Interventions: DEVICE: ultrasound|DEVICE: OCT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p