pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Indicated Prevention Transdiagnostic Intervention for Adolescents At High Risk of Emotional Problems
Status: COMPLETED
Conditions: Anxiety Disorders and Symptoms|Depressive Symptoms
Interventions: BEHAVIORAL: PROCARE-I (UP-A for indicated purposes)|BEHAVIORAL: Active control condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Developing and Implementing Meaningful Activities Facilitators in Geriatric Short Stay
Status: NOT_YET_RECRUITING
Conditions: Geriatric Care
Interventions: OTHER: Control: per usual practice|OTHER: Intervention MAF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Neurodevelopmental Therapy-Bobath Approach in The Early Term of Stroke; Safe and Effective
Status: COMPLETED
Conditions: Stroke, Acute|Ischemic Stroke
Interventions: OTHER: Neurodevelopmental Therapy-Bobath group|OTHER: Standart Rehabilitation Group (SR group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Prevention of Dermal Toxicity Caused by Regorafenib by Traditional Chinese Medicine TDX105
Status: UNKNOWN
Conditions: Hand and Foot Skin Reaction|Colorectal Cancer Stage IV
Interventions: DRUG: Traditional chinese medicine TDX105|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Training Intervention and Attitudes Towards Genetics
Status: RECRUITING
Conditions: Cognitive Impairment|Hematologic Neoplasms|Hematopoietic Cell Transplant
Interventions: BEHAVIORAL: Lumosity|BEHAVIORAL: Lumosity (waitlist control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: "THE EFFECTS OF LOW LEVEL LASER THERAPY VERSUS STRAIN/COUNTER STRAIN TECHNIQUE IN ACUTE SOFT TISSUE INJURIES"
Status: UNKNOWN
Conditions: Hamstring Injury|Strain Counter Strain
Interventions: OTHER: physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Low-Intensity Statin Plus Ezetimibe Versus High-Intensity Statin Therapy on Risk of New-Onset Diabetes Mellitus (PROVE-DM)
Status: RECRUITING
Conditions: Pre Diabetes|ASCVD
Interventions: DRUG: high-intensity statin arm|DRUG: low-intensity statin plus ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of Abatacept Subcutaneous Plus Methotrexate in Inducing Remission in Adults With Very Early Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Abatacept|DRUG: Methotrexate|DRUG: Abatacept placebo|DRUG: Methotrexate placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Home Exercises With the Addition of a Corticosteroid Injection in Patients With Lateral Hip Pain in General Practice
Status: UNKNOWN
Conditions: Lateral Hip Pain|Gluteal Tendinopathy|Greater Trochanteric Pain Syndrome
Interventions: COMBINATION_PRODUCT: Exercises and CSI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Digital SpyGlass Confirmed Common Bile Duct Stones Clearance Without Fluoroscopy
Status: COMPLETED
Conditions: Common Bile Duct Diseases|Stone - Biliary|Cholangitis, Sclerosing
Interventions: PROCEDURE: Endoscopic Retrograde Cholangioscopy by SpyGlass (ERCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Brain Imaging With Nuclear Technology in Individuals With Parkinsonian Syndrome
Status: COMPLETED
Conditions: Parkinson's Disease|Parkinsonian Syndrome
Interventions: DRUG: [123I]ß-CIT and SPECT imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mitomycin-C Injection Therapy in Refractory Esophageal Stricture
Status: COMPLETED
Conditions: Esophageal Stricture
Interventions: PROCEDURE: Endoscopic injection of Mitomycin-C on bougie-dilated refractory benign esophageal stricture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Strategies to Realize Apnea Test for the Diagnostic of Brain Death in Potential Organ Donors (CPAPNEE STUDY)
Status: COMPLETED
Conditions: Alternative Method of Apnea Test
Interventions: PROCEDURE: Apnea test - control|PROCEDURE: Apnea test - CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Safety, Tolerability and Pharmacokinetic Study of Multiple Doses of CS-8958
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: CS-8958|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 68Ga-AlfatideII for the Differential Diagnosis of of Lung Cancer and Lung Tuberculosis by PET/CT
Status: COMPLETED
Conditions: Lung Cancer|Lung Tuberculosis
Interventions: RADIATION: 68Ga-labeled peptides of dimer RGD (Alfatide II) and 18F-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intervention Effect of Transcranial Alternating Current Stimulation(tACS) on Anxiety Disorder
Status: RECRUITING
Conditions: Transcranial Alternating Current Stimulation|Anxiety Disorder|Magnetic Resonance Imaging
Interventions: DEVICE: transcranial alternating current stimulation|DEVICE: sham transcranial alternating current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Rising Dose Tolerability Study of BIBN 4096 BS in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBN 4096 BS- in single rising doses|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Radial Shockwave Versus Ultrasound Phonophoresis
Status: NOT_YET_RECRUITING
Conditions: Supraspinatus Tendinitis
Interventions: OTHER: Electro Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-77474462 (Bermekimab) in Healthy Participants of Japanese Descent Following Administration of Single Ascending Subcutaneous Doses
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-77474462|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Phase 4 Study of Efficacy and Safety of Apremilast in Subjects With Moderate Plaque Psoriasis.
Status: COMPLETED
Conditions: Parapsoriasis
Interventions: DRUG: Apremilast|DRUG: Placebo|DRUG: Placebo-Apremilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Efficacy of Osimertinib and EGFR T790M Status and Ratio Via ddPCR in NSCLC
Status: UNKNOWN
Conditions: EGFR T790M|Osimertinib|Non-small Cell Lung Cancer|ddPCR
Interventions: DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bioequivalence Study of Two Formulations of Sildenafil Tablet 100 mg in Healthy Male Volunteers Under Fasting Conditions
Status: UNKNOWN
Conditions: Bioequivalence
Interventions: DRUG: Sildenafil film-coated tablet 100 mg|DRUG: Viagra® film-coated tablet 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Open Label Extension Study to Evaluate the Safety of Continued Therapy of Subcutanous Remodulin® in Pulmonary Arterial Hypertension
Status: WITHDRAWN
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Subcutaneous Treprostinil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Platinum-based Chemotherapy + Bevacizumab + Durvalumab, and Salvage SBRT for IV Non-Small Cell Lung Cancer Patients With EGFR Mutations After Failure of First Line Osimertinib: A Multicenter, Prospective, Phase II Clinical Study
Status: UNKNOWN
Conditions: Lung Cancer Stage IV，EGFR-mutant，TKI，PD-L1，SBRT
Interventions: DRUG: pemetrexed，cisplatin/carboplatin，bevacizumab，durvalumab，SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3D CT Guidance for Transjugular Intrahepatic Portosystemic Shunt Creation
Status: UNKNOWN
Conditions: Portal Hypertension
Interventions: DEVICE: CT-image guidance|DRUG: CO2 portograms guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Azilsartan Medoxomil Combined With Chlorthalidone in Participants With Moderate to Severe Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Azilsartan medoxomil and chlorthalidone|DRUG: Azilsartan medoxomil and chlorthalidone|DRUG: Azilsartan medoxomil and chlorthalidone|DRUG: Azilsartan medoxomil and chlorthalidone|DRUG: Azilsartan medoxomil and chlorthalidone|DRUG: Azilsartan medoxomil and chlorthalidone|DRUG: Chlorthalidone|DRUG: Chlorthalidone|DRUG: Azilsartan medoxomil|DRUG: Azilsartan medoxomil|DRUG: Azilsartan medoxomil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Insulin Detemir Versus NPH Insulin In Hospitalized Patients With Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Detemir + aspart insulin before meals|DRUG: NPH insulin + regular insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis- (ATTEST)
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Tenecteplase|DRUG: alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioavailability of Cefzil 500 mg Cefprozil Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cefprozil 500 mg Tablets (Sandoz GmbH)|DRUG: Cefzil (Cefprozil) 500 mg Tablets (Bristol-Myers Squibb)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Efgartigimod PH20 SC Given by Prefilled Syringe in Adults with Thyroid Eye Disease.
Status: RECRUITING
Conditions: Thyroid Eye Disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduction in YEllow Plaque by Aggressive Lipid LOWering Therapy
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: standard of care lipid therapy|DRUG: Aggressive lipid therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RSV F Vaccine Maternal Immunization Study in Healthy Third-trimester Pregnant Women.
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: Saline Placebo (0.5mL injection)|DRUG: RSV F vaccine (0.5mL injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pain Neuroscience Education and Motor Imagery-based Exercise Protocol for Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia|Pain|Psychology Regression
Interventions: BEHAVIORAL: Pain neuroscience education (PNE)|BEHAVIORAL: Motor imagery-based exercise protocol (MIEP)|BEHAVIORAL: Combination Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prediction of Radiotherapy Efficacy in Patients With Triple-negative Breast Cancer
Status: RECRUITING
Conditions: Triple-negative Breast Cancer
Interventions: BIOLOGICAL: blood sampling before radiotherapy|BIOLOGICAL: blood sampling after the fourth radiotherapy session|OTHER: collection of acute toxicity (radiodermatitis)|OTHER: collection of late toxicity|OTHER: collection of disease status|RADIATION: Radiotherapy - Breast +/- lymph node areas|RADIATION: Radiotherapy - Boost operating bed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Bioequivalence Study of Two Different PEG-rhGH Preparations.
Status: NOT_YET_RECRUITING
Conditions: Pediatric Growth Hormone Deficiency (PGHD)
Interventions: DRUG: PEG-rhGH with new preparation (T)|DRUG: PEG-rhGH with present preparation (R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of a Web-based Advance Directive to a Standard Advance Directive
Status: COMPLETED
Conditions: GI Cancer|Thoracic Cancer
Interventions: OTHER: Web platform for advance care planning/advance directive|OTHER: Standard advance directive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Surrogate Markers of Response to New Therapies in Cystic Fibrosis Patients
Status: RECRUITING
Conditions: Cystic Fibrosis
Interventions: PROCEDURE: Nasal swab; rectal biopsy.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of ZG005 in Combination With Etoposide and Cisplatin in Participants With Advanced Neuroendocrine Carcinoma.
Status: RECRUITING
Conditions: Neuroendocrine Carcinoma
Interventions: BIOLOGICAL: ZG005|DRUG: Etoposide|DRUG: Cisplatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized Control Trial on Seprafilm and Guardix in Preventing Ileus
Status: COMPLETED
Conditions: Patient Under Going Colorectal and Stomach Cancer Surgery
Interventions: PROCEDURE: Guardix|PROCEDURE: Seprafilm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacologic Equivalence of Two Orlistat Dosage Forms
Status: COMPLETED
Conditions: Overweight
Interventions: DRUG: 120 mg orlistat|DRUG: 60 mg orlistat|DRUG: orlistat experimental dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Assessment of the Therapeutic Efficacy and Tolerability of the Artesunate/Amodiaquina Combination and Artemether/Lumefantrine Combination, Treatment of Uncomplicated P. Falciparum Malaria in the Department of Chocó (Colombia)
Status: COMPLETED
Conditions: P. Falciparum Malaria
Interventions: DRUG: Artemeter plus lumefantrina vs artesunato plus amodiquina
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dissolved Oxygen Dressing to Improve Chronic Wound Healing After Revascularization for Critical Limb Ischemia
Status: TERMINATED
Conditions: Critical Limb Ischemia
Interventions: DEVICE: Oxygenesys(TM) Dissolved Oxygen Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Of Striatal Glucose Metabolism With Positron Emission Tomography Following PF-02545920 In Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-02545920|DRUG: placebo|DRUG: PF-02545920|DRUG: PF-02545920|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Periodontal Treatment in Patients With Bronchiectasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Bronchiectasis|Periodontal Disease
Interventions: PROCEDURE: supragingival treatment|PROCEDURE: periodontal treatment|PROCEDURE: periodontal treatment and photodynamic therapy|OTHER: dental hygiene orientation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double Blind Sham Controlled Trial of tDCS in Treating Schizophrenia and Depression
Status: COMPLETED
Conditions: Schizophrenia|Major Depression
Interventions: DEVICE: transcranial direct current stimulation (tDCS)|DEVICE: active tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-aortic Balloon Pump in Extensive Myocardial Infarction With Persistent Ischemia
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Persisting Ischemia|No Reflow
Interventions: DEVICE: Intra-aortic balloon pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Select Combinations in Adults With Myelofibrosis
Status: WITHDRAWN
Conditions: Primary Myelofibrosis|Myelofibrosis|PMF|Post-Essential Thrombocythemia Myelofibrosis|Post-Polycythemia Vera Myelofibrosis
Interventions: DRUG: MBG453|DRUG: NIS793|DRUG: Spartalizumab|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Portion of Phase I/II Sorafenib With Radiation and Temozolomide in Newly Diagnosed Glioblastoma or Gliosarcoma
Status: TERMINATED
Conditions: Glioblastoma|Gliosarcoma
Interventions: DRUG: Temozolomide|RADIATION: Radiation|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Oil, Fats and Oleogel Study
Status: COMPLETED
Conditions: Glycaemic Response and Energy Balance
Interventions: OTHER: Congee and juice with coconut gel|OTHER: Congee and juice with coconut oil|OTHER: Congee and juice with sunflower gel|OTHER: Congee and juice with sunflower oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects Of Power Ball Exercises In Addition To Routine Physical Therapy In Patients With Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Routine Physical Therapy|OTHER: Powerball Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RTL Concussion Communication
Status: NOT_YET_RECRUITING
Conditions: Concussion, Mild|Post Concussion Symptoms|Cognitive Impairments|Cognitive Impairments, Mild|Multidisciplinary Care Team|Team Nursing|Sports Injuries in Children|Learning Disturbance
Interventions: BEHAVIORAL: InjureFree
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bemarituzumab Plus Chemotherapy and Nivolumab Versus Chemotherapy and Nivolumab for FGFR2b Overexpressed Untreated Advanced Gastric and Gastroesophageal Junction Cancer.
Status: RECRUITING
Conditions: Gastric Cancer|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Bemarituzumab|DRUG: Nivolumab|DRUG: Chemotherapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single and Multiple Dose Evaluation of ABT-072 and to Evaluate the Effect of Food on the Pharmacokinetics of ABT-072
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: ABT-072|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: PD-1 Knockout Anti-MUC1 CAR-T Cells in the Treatment of Advanced Breast Cancer
Status: COMPLETED
Conditions: Advanced Breast Cancer|Breast Neoplasm Malignant Female
Interventions: DRUG: AJMUC1- PD-1 gene knockout anti-MUC1 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xenodiagnosis After Antibiotic Treatment for Lyme Disease
Status: COMPLETED
Conditions: Lyme Disease
Interventions: PROCEDURE: Skin biopsy|PROCEDURE: Blood draw|DEVICE: Xenodiagnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Therapeutic Benefit of an Initial Intensified Dosing Regimen of Mycophenolate Sodium Versus a Standard Regimen in Renal Transplant Patients
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Enteric-coated mycophenolate sodium (Myfortic)|DRUG: Cyclosporine (Neoral)|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Antitumor Activity of KN046 in Subjects With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Solid Tumors
Interventions: DRUG: KN046
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oliceridine in Patients With Acute Burn Injuries
Status: COMPLETED
Conditions: Acute Pain|Burns|Adverse Drug Event|Respiratory Depression|Nausea and Vomiting, Postoperative
Interventions: DRUG: Oliceridine|DRUG: Historical opioid use
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open, Randomized Pilot Study to Evaluate the Use of Basiliximab With an Optimized Cyclosporine Dosing on Renal Function in "de Novo" Liver Transplantation.
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DRUG: Basiliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of ASP1941 in Combination With Metformin in Asian Diabetes Patients
Status: COMPLETED
Conditions: Type II Diabetes Mellitus
Interventions: DRUG: ASP1941|DRUG: metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ZT002 Injection in Participants With Overweight or Obesity
Status: ENROLLING_BY_INVITATION
Conditions: Overweight or Obesity
Interventions: DRUG: ZT002 Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety and Tolerability of LY3938577 in Healthy Participants and Participants With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Healthy|Type 2 Diabetes Mellitus
Interventions: DRUG: LY3938577|DRUG: Placebo|DRUG: Insulin degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Consuming Whey Protein Polydextrose Snacks on Appetite and Energy Intake
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Whey-protein & polydextrose snack|DIETARY_SUPPLEMENT: Control snack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-183)
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: MK0966, rofecoxib|DRUG: Comparator: oxycodone with acetaminophen, placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of ECO-4601 in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Tumors|Glioma|Colorectal Cancer|Lung Cancer|Breast Cancer|Ovarian Cancer|Pancreatic Cancer|Prostate Cancer
Interventions: DRUG: ECO-4601
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiretroviral Treatment Simplification Study With Efavirenz + Abacavir + 3TC Once Daily
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: efavirenz|DRUG: Abacavir+lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging Studies and the Development of Multiple Myeloma
Status: WITHDRAWN
Conditions: Multiple Myeloma|Smoldering Multiple Myeloma|Monoclonal Gammopathy of Undetermined Significance
Interventions: DRUG: Fluciclatide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of AUY922 and Cetuximab in Patients With KRAS Wild-Type Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IV Colon Cancer|Stage IV Rectal Cancer|Adenocarcinoma of the Colon|Adenocarcinoma of the Rectum
Interventions: DRUG: AUY922|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: (QuANTUM-R): An Open-label Study of Quizartinib Monotherapy vs. Salvage Chemotherapy in Acute Myeloid Leukemia (AML) Subjects Who Are FLT3-ITD Positive
Status: COMPLETED
Conditions: AML
Interventions: DRUG: Quizartinib|DRUG: Salvage Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of 3 Anti-HIV Treatments in Patients Who Have Failed Previous Treatments Containing Nelfinavir
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Ritonavir|DRUG: Delavirdine mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Trial of Lenvatinib Plus Pembrolizumab in Participants With Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: lenvatinib|DRUG: pembrolizumab (200 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Nebivolol and Carvedilol on Diastolic Function in the Elderly Heart Failure Patients
Status: UNKNOWN
Conditions: Heart Failure
Interventions: DRUG: Nebivolol|DRUG: Carvedilol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3437943 in Postmenopausal Female Participants Who Are Overweight or Obese
Status: COMPLETED
Conditions: Overweight
Interventions: DRUG: LY3437943|DRUG: Ethinyl Estradiol|DRUG: Drospirenone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Single Dose FMT Infusion as an Adjunct to Keytruda for Metastatic Mesothelioma
Status: COMPLETED
Conditions: Mesothelioma
Interventions: BIOLOGICAL: Fecal Microbiota Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: One Year Clinical Evaluation of Shade Matching and Patient Satisfaction of New Gradient Technology Monolithic Zirconia (5Y-TZP\3Y-TZP) Compared to Lithium Disilicate Crowns in Dental Esthetic Zone
Status: UNKNOWN
Conditions: Decayed Teeth|Malposed Teeth|Endodontically Treated Teeth|Teeth Restored With Large Filling Restorations|Single Anterior Crowns|Single Premolars Crowns
Interventions: OTHER: lithium disilicate (IPS e-max) ceramic crown|OTHER: New gradient technology zirconia (5Y-TZP\ 3Y-TZP) IPS e.max ZirCad Prime ceramic crown|OTHER: natural tooth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Colchicine Or Naproxen Treatment for ACute gouT
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: Low-dose colchicine|DRUG: Naproxen 750 mg/250 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation and Robotic Therapy in Upper Limb Motor Recovery After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: tDCS plus wrist robot therapy|DEVICE: Sham tDCS plus wrist robot therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Diagnostic Observatory: Combating Diagnostic Wandering and Impasse Within the AnDDI-Rares Network
Status: RECRUITING
Conditions: Developmental Abnormality
Interventions: OTHER: Questionnaire to assess expectations of a diagnosis|OTHER: Questionnaire to assess understanding of previously reported results and expectations of a diagnosis|BIOLOGICAL: Blood sample +/- skin biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Attention-Deficit Hyperactivity Disorder (ADHD) Rating Scale and Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: OTHER: ADHD Rating Scale-IV|OTHER: ADHD Rating Scale-IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Substance-focused SBI as a Complement to Internet-based Psychiatric Treatment: RCT
Status: COMPLETED
Conditions: Substance Use Disorders (SUD)
Interventions: BEHAVIORAL: eScreen|BEHAVIORAL: Assessment only of alcohol and drug use.|BEHAVIORAL: Internet-based treatment for depression or anxiety
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Muscle Strength in Shoulder and Neck Muscles in Tension Type Headache Patients. Effect of Specific Strength Training
Status: COMPLETED
Conditions: Tension-Type Headache
Interventions: OTHER: Strength training|OTHER: Ergonomic and posture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Intensive Monitoring and Preemptive Intervention in the Maintenance of AVF
Status: UNKNOWN
Conditions: Vascular Access Malfunction|Vascular Access Complication|Vascular Access Site Occlusion
Interventions: OTHER: Intensified Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Heparin for the Treatment of Burn Wound Pain
Status: UNKNOWN
Conditions: Second Degree Burns
Interventions: DRUG: Polyfax & Lignocain gel or silvazine cream|DRUG: Topical Heparin|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Doubling the Maintenance Dose of Clopidogrel in Patients With High On-Clopidogrel Platelet Reactivity
Status: TERMINATED
Conditions: Stable Angina Pectoris|Ad Hoc Percutaneous Coronary Intervention
Interventions: DRUG: clopidogrel|DRUG: clopidogrel plus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Donor T Cell Therapy in Treating Immunocompromised Patients With Adenovirus-Related Disease
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Immunocompromised
Interventions: BIOLOGICAL: Allogeneic Adenovirus-specific Cytotoxic T Lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Implantation of Biologic Mesh in Peritonitis
Status: UNKNOWN
Conditions: Incisional Hernia|Peritonitis
Interventions: DEVICE: biological prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of QAW039 in Sputum Eosinophilia and Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: QAW039|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Cusatuzumab Plus Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia Who Are Not Candidates for Intensive Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Azacitidine|DRUG: Cusatuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Optimal Dose of Sufentanil in Patient Controlled Analgesia After Moderate Surgery
Status: UNKNOWN
Conditions: Analgesia, Patient-Controlled|Gastrectomy|Arthroplasty
Interventions: DRUG: Sufentanil|DRUG: Sufentanil|DRUG: Sufentanil|DRUG: Midazolam|DRUG: propofol|DRUG: cisatracurium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Enhancement in Healthy Elderly People
Status: UNKNOWN
Conditions: Transcranial Direct Current Stimulation|Transcranial Alternating Current Stimulation
Interventions: DEVICE: tDCS or tACS over the left DLPFC with adaptive memory game|DEVICE: Sham tDCS or tACS over the left DLPFC with adaptive memory game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Administration of Somatostatin in the Prevention of Post-endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis
Status: UNKNOWN
Conditions: Acute Pancreatitis
Interventions: OTHER: fisiologic serum|DRUG: somatostatin, intravenous bolus|DRUG: somatostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Social Work Intervention Focused on Transitions
Status: COMPLETED
Conditions: Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention|Heart Disease|Diabetes|Hypertension|Cancer|Depression|Asthma|Chronic Heart Failure|Chronic Obstructive Pulmonary Disease|Stroke
Interventions: OTHER: SWIFT home intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Galcanezumab (LY2951742) in Participants 12 to 17 Years of Age With Chronic Migraine
Status: RECRUITING
Conditions: Chronic Migraine
Interventions: DRUG: Galcanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of CRE8 Drug Eluting Stent in All Comer Population
Status: COMPLETED
Conditions: Stable Angina|Unstable Angina|Acute Myocardial Infarction
Interventions: DEVICE: Amphilimus Eluting Stent (CRE8)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Application of Magnetic Fields for the Treatment of Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson's Disease|Quality of Life
Interventions: DEVICE: Resonator Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Bapineuzumab In Alzheimer Disease Subjects
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: bapineuzumab|DRUG: bapineuzumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of KPG-818 in Healthy Subjects
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: KPG-818
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Testing During Treadmill Gait in Incomplete Spinal Cord Injury
Status: UNKNOWN
Conditions: Spinal Cord Injury
Interventions: DEVICE: Treadmill with partial body weight support|DEVICE: Surface Functional Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: ECT
Clinical trial: Evaluation of the Role of Connected Scales in the Therapeutic Care of Hematology Patients
Status: NOT_YET_RECRUITING
Conditions: Lymphoma, Non-Hodgkin|Myeloma Multiple
Interventions: DEVICE: Connected scale "Body Comp Pro" from Withings
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Post-operative Pain and Expression of IL-8 Using Ketolac or Cryoirrigation as a Final Flush in Single Visit Endodontic Treatment in Teeth With Symptomatic Irreversible Pulpitis and Apical Periodontitis.Randomized Clinical Trial.
Status: UNKNOWN
Conditions: Post-operative Pain
Interventions: DRUG: Ketorolac Tromethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alcohol, Inflammation and Atherosclerosis
Status: COMPLETED
Conditions: Arteriosclerosis|Myocardial Infarction
Interventions: DRUG: red wine, beer, ethanol|DRUG: de-alcoholised red wine, de-alcoholised beer, water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Microbiota and Quality of Life for a Low FODMAPs and Standard Dietary in Irritable Bowel Syndrome Patients
Status: UNKNOWN
Conditions: Food Habits
Interventions: BEHAVIORAL: Low FODMAPs Diet|BEHAVIORAL: Diet instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ASN007 in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Cancer|Malignancy|Neoplasia|Neoplasm|Neoplasm Metastasis|Colon Cancer|Colonic Neoplasms|Colon Cancer Liver Metastasis|Metastatic Cancer|Metastatic Melanoma|Metastatic Colon Cancer|Metastatic Lung Cancer|Non Small Cell Lung Cancer Metastatic|Pancreatic Cancer|Pancreas Cancer|Pancreas Adenocarcinoma|Pancreas Neoplasm|Metastatic Nonsmall Cell Lung Cancer|Metastatic Pancreatic Cancer
Interventions: DRUG: ASN007: ascending doses|DRUG: ASN007 RD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Parent Administered Sensorimotor Intervention and Developmental Outcome of Preterm Infants
Status: COMPLETED
Conditions: Premature Infant|Developmental Delay
Interventions: OTHER: Sensorimotor intervention|OTHER: Control|OTHER: Story telling attention refocusing intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: S-1, Irinotecan, and Oxaliplatin in Locally-Advanced Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Tegafur-gimeracil-oteracil potassium|DRUG: Oxaliplatin|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diffusion Weighted Magnetic Resonance Imaging for Preoperative Staging in Gastric Adenocarcinoma Patients
Status: COMPLETED
Conditions: Gastric Adenocarcinoma
Interventions: PROCEDURE: diffusion weighted magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Office Hysteroscopy and Endometrial Snip Improve Intrauterine Insemination Outcome
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: Office hysteroscopy and endometrial snip|PROCEDURE: Office hysteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ABX-EGF (a Monoclonal Antibody) Given to Patients With Prostate Cancer With or Without Tumor in Other Parts of the Body
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: ABX-EGF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CRUSH-PrEP for Women Project
Status: COMPLETED
Conditions: Sexually Transmitted Diseases|HIV
Interventions: OTHER: Pre Exposure Prophylaxis|BEHAVIORAL: Characteristics of women who enroll|BEHAVIORAL: referral sources of women who enroll
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cemiplimab and Cetuximab Prior Salvage Surgery in Patients With Recurrent Oral Cavity Squamous Cell Carcinoma (OCSCC).
Status: NOT_YET_RECRUITING
Conditions: Locally Recurrent Oral Cavity Squamous Cell Carcinoma
Interventions: DRUG: Cemiplimab|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autism and Disruptive Behavior Trial
Status: COMPLETED
Conditions: ASD|Child Behavior Problem
Interventions: BEHAVIORAL: Social Worker|BEHAVIORAL: Autism Behavioral Health Navigation (ABHN)|BEHAVIORAL: Social work + ABHN|BEHAVIORAL: Social work + ABHN + CAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Radiological Characterization of Pulmonary Involvement in Patients With Hematological Diseases
Status: NOT_YET_RECRUITING
Conditions: Hematologic Diseases
Interventions: DIAGNOSTIC_TEST: Complete Blood Count|DIAGNOSTIC_TEST: C-reactive protein|DIAGNOSTIC_TEST: O2 saturation|DIAGNOSTIC_TEST: Serum ferritin and D-dimer|DIAGNOSTIC_TEST: Liver and renal function tests|DIAGNOSTIC_TEST: Lactate dehydrogenase|DIAGNOSTIC_TEST: coronavirus (SARS-CoV-2) swab|RADIATION: CT chest
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: En Bloc Resection Versus Separation Surgery Combined With Radiotherapy for the Treatment of Spinal Oligometastatic Tumor.
Status: RECRUITING
Conditions: Spinal Metastases|Spinal Tumor|Radiotherapy|Malignant Bone Tumor|Surgery
Interventions: PROCEDURE: total en bloc spondylectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study That Uses Data From Routine Eye Examinations of Patients Participating in Studies FIDELIO-DKD and FIGARO-DKD to Explore Whether Finerenone Can Delay the Progression of a Diabetes Complication That Affects the Eyes (Diabetic Retinopathy, DR)
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DRUG: Finerenone (BAY94-8862)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Test the Design, Functionality, and Ergonomic Features of the Autoinjector
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Psoriatic Arthritis|Ankylosing Spondylitis|Psoriasis
Interventions: DEVICE: Pre-filled Auto-injector Containing Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesothelin-targeted CAR T-cell Therapy in Patients With Mesothelioma
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Pleural Mesothelioma (MPM)
Interventions: DRUG: cyclophosphamide|BIOLOGICAL: CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT