pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Trial of Oral Versus Intravenous Proton Pump Inhibitor on Intragastric pH in Patients With Bleeding Ulcers
Status: COMPLETED
Conditions: Peptic Ulcer Hemorrhage
Interventions: DRUG: Proton pump inhibitor (lansoprazole)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Cemiplimab Combined With Dabrafenib and Trametinib in People With Anaplastic Thyroid Cancer
Status: RECRUITING
Conditions: Anaplastic Thyroid Cancer|Thyroid Cancer|BRAF Gene Mutation|BRAF Mutation-Related Tumors
Interventions: DRUG: Dabrafenib|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Lifestyle Intervention on Gestational Diabetes Management
Status: COMPLETED
Conditions: Gestational Diabetes|Type 2 Diabetes|Nutritional and Metabolic Disease
Interventions: BEHAVIORAL: Dietary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Inhalation of 20,000 EU CCRE in Normal Volunteers Compared to Allergic Asthmatic Individuals
Status: COMPLETED
Conditions: Asthma|Hypersensitivity
Interventions: BIOLOGICAL: Clinical Center Reference Endotoxin (CCRE)|BIOLOGICAL: Clinical Center Reference Endotoxin (CCRE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Insertion Clinical Study to Evaluate the Orientation Characteristics of Multiple Kalifilcon A Daily Disposable Toric LD213001 Contact Lenses
Status: COMPLETED
Conditions: Astigmatism
Interventions: DEVICE: kalifilcon A Daily Disposable Toric LD213001 Contact Lenses|DEVICE: Commercially available Ultra for Astigmatism Contact Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Stimulation of STN and SNr for Dysphagia in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson's Disease|Dysphagia
Interventions: DEVICE: [standard STN]|DEVICE: [STN+SNr]|BEHAVIORAL: Swallowing therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics and Hospital Outcome in the Elderly
Status: COMPLETED
Conditions: Diarrhea|Constipation
Interventions: DIETARY_SUPPLEMENT: VSL#3|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Biomechanical and Viscoelastic Properties of Thoracolumbar Fascia in Pregnancy Pelvic Girdle Pain
Status: UNKNOWN
Conditions: Pregnant Women|Pelvic Girdle Pain
Interventions: OTHER: Evaluation of pain|DIAGNOSTIC_TEST: Application of pelvic girdle diagnostic tests|OTHER: Evaluation of biomechanics and viscoelastic properties of thoracolumbar fascia|OTHER: Evaluation of activity limitation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Perioperative Administration of Tranexamic Acid for Placenta Previa and Accreta Study
Status: COMPLETED
Conditions: Placenta Accreta|Postpartum Hemorrhage|Cesarean Section|Tranexamic Acid
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Outpatient Pediatric Pulse Oximeters in Africa
Status: NOT_YET_RECRUITING
Conditions: Child|Infant|Respiratory Tract Infections|Hypoxia
Interventions: DEVICE: Phefumla device|DEVICE: LB-01 device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Safety And Efficacy Of Atorvastatin In Patients With Diabetes And High Cholesterol
Status: COMPLETED
Conditions: Hyperlipidemias
Interventions: DRUG: atorvastatin|DRUG: atorvastatin|DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Inhaler Device Attributes Investigating Critical and Overall Errors, Ease of Use, and Preference Between a Number of Inhaler Devices
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: ELLIPTA|DEVICE: DISKUS/ACCUHALER|DEVICE: MDI|DEVICE: TURBUHALER|DEVICE: HANDIHALER|DEVICE: BREEZEHALER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pharmacodynamic and Pharmacokinetic Study of 2 Different Dose Regimen of Clopidogrel in CYP2C19 Genotyped Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CLOPIDOGREL|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Aim of Study is Translate and Adapt the Visual Analog Scale Foot and Ankle (VAS-FA) Instrument Into Turkish and Psycho-metrically Test Its Reliability and Validity Among Patients Who Had Foot and Ankle Disorders or Surgery
Status: COMPLETED
Conditions: Ankle Injuries and Disorders|Foot Injuries and Disorders
Interventions: OTHER: VAS-FA Turkish version
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Double-blinded, Randomised, Two -Period Crossover Euglycemic Clamp Trial Investigating the Pharmacokinetics, Glucodynamics and Safety of BioChaperone Insulin Lispro and Insulin Lispro (Humalog®) in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus Type 1
Interventions: DRUG: BioChaperone insulin lispro|DRUG: Humalog®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Insulin Exposure and Glucose Response to Meals in Type 1 Diabetic Subjects Administered Two Different Insulin Regimens Compared to the Endogenous Insulin Exposure and Glucose Response to Meals In Healthy Adult Controls
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Insulin glulisine|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Odense Androgen Study - The Effect of Testim and Training in Hypogonadal Men
Status: UNKNOWN
Conditions: Hypogonadism|Metabolic Syndrome
Interventions: DRUG: Testim|BEHAVIORAL: Strength training|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation for Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer Disease|Dementia, Alzheimer Type|Deep Brain Stimulation
Interventions: DEVICE: Deep brain stimulation|DRUG: Best medical treatment for Alzheimer's disease
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pazopanib to Treat Adults With Advanced Cancers and Varying Degrees of Liver Function
Status: COMPLETED
Conditions: Neoplasms|Lymphoma
Interventions: DRUG: Pazopanib|DRUG: Pazopanib (GW786034)(GW786034)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TARA Working Prototype [Version 2]: Feasibility Study
Status: WITHDRAWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: Technology-Assisted Respimat Adherence Digital Behaviour Change Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Impact of Monosodium Glutamate on 68GA-PSMA-11, PET Imaging Biodistribution in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Gallium Ga 68-labeled PSMA-11|DIETARY_SUPPLEMENT: Monosodium Glutamate|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: PRIMEx - A Study of 2 Doses of Oral CXA-10 in Pulmonary Arterial Hypertension (PAH)
Status: TERMINATED
Conditions: PAH
Interventions: DRUG: 75mg CXA-10|DRUG: 150mg CXA-10|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan/Oxaliplatin/5-Fluorouracil/Leucovorin/Cetuximab As First Line Treatment In Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Irinotecan|DRUG: Leukovorin|DRUG: Oxaliplatin|DRUG: 5-FLUOROURACIL|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab Deruxtecan (T-DXd) With Pyrotinib in First-line HER2-positive Unresectable or Metastatic Breast Cancer Trial
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Trastuzumab deruxtecan (T-DXd) with pyrotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAR-T-19 Injection in the Treatment of CD19-positive Relapsed/Refractory B-ALL
Status: RECRUITING
Conditions: Relapsed B-cell Acute Lymphoblastic Leukemia|Refractory B-cell Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: CAR-T-19 cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microfidelity (MIFI) Ablation Technology Versus Standard Ablation Catheter for Atrioventricular Nodal Ablation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: MIFI Catheter|DEVICE: Standard Ablation Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-pigmenting Effect of a Routine of Facial Products in Subjects With Melasma
Status: NOT_YET_RECRUITING
Conditions: Melasma
Interventions: OTHER: Liftactiv® B3 Serum|OTHER: Liftactiv® B3 retinol night cream|OTHER: Sunscreen UVAage® Inter SPF 50+|OTHER: Mineral 89 cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility & Acceptability of a Patient-Oriented Music Intervention to Reduce Pain in the Intensive Care: A Pilot Trial
Status: UNKNOWN
Conditions: Pain, Acute|Distress, Emotional|Critical Illness
Interventions: OTHER: Patient-Oriented Music Intervention (POMI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stress-related Predictor Profiles in Human Addiction
Status: COMPLETED
Conditions: Alcohol Use Disorder|Stress Reaction|Social Stress|Craving|Relapse|Addiction|Risk Behavior
Interventions: BEHAVIORAL: Trier Social Stress Test|BEHAVIORAL: Ergometer|BEHAVIORAL: Barlab-Exposure|BEHAVIORAL: Reading Newspaper
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of HIPEC in the Treatment of Patients With Locally Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Advanced Gastric Adenocarcinoma
Interventions: PROCEDURE: D2 lymphadenectomy|PROCEDURE: Systemic chemotherapy|PROCEDURE: HIPEC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATALANTE: Atezolizumab vs Placebo Phase III Study in Late Relapse Ovarian Cancer Treated With Chemotherapy+Bevacizumab
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: atezolizumab + avastin + platinum-based chemotherapy|DRUG: placebo + avastin + platinum-based chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Followed by Radiation Therapy in Treating Children With Localized Ependymoma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: cyclophosphamide|DRUG: etoposide|DRUG: vincristine sulfate|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparing Optical Coherence Tomography (OCT) and Visual Acuity Outcomes in Subjects Undergoing Cataract Surgery, Who Receive Xibrom Ophthalmic Solution and Standard Presurgical Care vs. Xibrom Ophthalmic Solution Plus Prednisolone Acetate 1% and Standard Presurgical Care
Status: COMPLETED
Conditions: Cataracts
Interventions: DRUG: Xibrom, and Optive|DRUG: Xibrom and Pred Forte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Anti-emetic Effect of Aprepitant Versus Placebo in Children and Adolescent Receiving Chemotherapy
Status: COMPLETED
Conditions: Chemotherapy Induced Nausea and Vomiting
Interventions: DRUG: Aprepitant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Social and Monetary Incentives for Smoking Cessation at Large Employers
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: BEHAVIORAL: Usual Care|BEHAVIORAL: Deposits|BEHAVIORAL: Small Individual Bonus|BEHAVIORAL: Large Individual Bonus|BEHAVIORAL: Teammate|BEHAVIORAL: Team Bonus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine and Dexmedetomidine Comparative Study
Status: NOT_YET_RECRUITING
Conditions: Post Operative Pain
Interventions: PROCEDURE: combined ultra-sound guided femoral and sciatic nerve block.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Reducing Risks and Improving Glucose Control During Extended Exercise in Youth With T1DM: The AP Ski Camp
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: Closed-Loop Control|OTHER: Sensor Augmented Pump Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Varying Energy Deficits on Protein Turnover at Rest and Carbohydrate Oxidation During Steady-state Exercise
Status: RECRUITING
Conditions: Energy Supply; Deficiency, Severe|Energy Supply; Deficiency|Stress, Physiological
Interventions: OTHER: Energy Deficit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immune Response of Individuals Vaccinated With Hypoallergenic Derivatives of the Major Birch Pollen Allergen, Bet v 1
Status: UNKNOWN
Conditions: Allergy
Interventions: BIOLOGICAL: Bet v 1aF1-Alum + Bet v 1aF2-Alum|BIOLOGICAL: Alum-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Perioperative Cancer Cell Dissemination and Systemic Immune Suppression in Resectable Ductal Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Neoplasms|Adenocarcinoma|Neoplasm Circulating Cells|Tumor Markers, Biological|Monitoring, Immunologic
Interventions: PROCEDURE: Pancreatic resection (PD)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multicentre Evaluation of Bucco-dental Health in Patients With Schizophrenia in Côte d'Or
Status: COMPLETED
Conditions: Schizophrenia
Interventions: OTHER: Bucco-dental examination|OTHER: Blood sample|OTHER: Clinical and social questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: An Interventional Study to Evaluate the Safety and Performance of Crosslinked Hyaluronic Acid Hydrogel
Status: RECRUITING
Conditions: Dermal Filler|Volume Deficiency of the Midface
Interventions: DEVICE: Crosslinked Hyaluronic Acid (CLHA) Hydrogel with and without Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pregabalin Versus Gabapentin Opioid Sparing Effect in Discectomy
Status: ENROLLING_BY_INVITATION
Conditions: Opioid Use
Interventions: DRUG: Pregabalin 150mg gabapentin 400mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Combination of Immunotherapy and Stereotactic Ablative Radiotherapy in MSS Oligometastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: RADIATION: Stereotactic Ablative Radiotherapy (SABR)|DRUG: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neck Muscle Activation in Patients With Long Standing Problems After a Whiplash Trauma Registered With Ultrasound With Speckle Tracking
Status: COMPLETED
Conditions: Whiplash Associated Disorder
Interventions: OTHER: Neck specific exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Lowdose Nivolumab in Combination With AVD as Front Line Therapy for Classic Hodgkin's Lymphoma
Status: RECRUITING
Conditions: Safety Issues|Efficacy, Self
Interventions: DRUG: low dose nivolumab in combination with AVD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intermittent Exercise Training Programs in Patients With Myocardial Infarction
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: OTHER: Intermittent Exercise|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanism of Chronic Pain in Patients With IBD
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases
Interventions: OTHER: Assessment of Psychophysiological factors|BIOLOGICAL: Assessment of Biological factors|GENETIC: Assessment of Genetics|BEHAVIORAL: Assessment of Quality of Life|BIOLOGICAL: Assessment of Biological factors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The BoDI (Bone Density Investigation) Study
Status: NOT_YET_RECRUITING
Conditions: Cerebral Palsy
Interventions: RADIATION: Digital X-Ray Radiogrammetry|DIAGNOSTIC_TEST: Quantitative Ultrasound (QUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of the Effects of Balance-proprioception and Aerobic Exercises on Functional Status and Strength Parameters in Patients With Fibromyalgia.
Status: COMPLETED
Conditions: Fibromyalgia Syndrome
Interventions: OTHER: therapeutic exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Body Composition, Food Consumption, and Micro and Macronutrients With Gene Expression in Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Endocrine Therapy|Endocrine Therapy Adverse Reaction|Vitamin D Deficiency|Nutrition Disorders|Obesity
Interventions: DRUG: Tamoxifen|DRUG: Exemestane|DRUG: Anastrozole|DIAGNOSTIC_TEST: Basal|DIAGNOSTIC_TEST: Recurrence
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Estetrol/Drospirenone to Reduce the Average Size of Endometriomas
Status: NOT_YET_RECRUITING
Conditions: Ovarian Endometrioma|Endometrioma
Interventions: DRUG: Estetrol/Drospirenone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Efficacy of Virtual Reality Analgesia (VRA) in Pediatric Patients for Pain Control
Status: TERMINATED
Conditions: Pain
Interventions: OTHER: Google Cardboard VRA|OTHER: Oculus Rift VRA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of V114 in Children Infected With Human Immunodeficiency Virus (HIV) (V114-030/PNEU-WAY PED)
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: V114|BIOLOGICAL: Prevnar 13™|BIOLOGICAL: PNEUMOVAX™23
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Chemotherapy for Patients With Cancer of the Stomach
Status: COMPLETED
Conditions: First-line Treatment for Patients With Non-resectable Gastric Cancer or Cancer of the Esophagus or
Interventions: DRUG: DOS2w Dose level 1A|DRUG: DOS2w Dose level 2A|DRUG: DOS2w Dose level 3A|DRUG: DOS2w Dose level 4A|DRUG: DOS3w Dose level 1B|DRUG: DOS3w Dose level 2B|DRUG: DOS3w Dose level 3B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Henagliflozin in Patients With Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DRUG: placebo|DRUG: Henagliflozin 5Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: BeGrow Study to Treat Pulmonary Artery (PA) Stenosis in Newborns and Infants
Status: UNKNOWN
Conditions: Pulmonary Artery Stenosis
Interventions: DEVICE: BeGrow Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electroconvulsive Therapy in Clozapine Refractory Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: PROCEDURE: Electroconvulsive Therapy (ECT)|DRUG: Clozapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ascending Dose and Exploratory Expansion Study of DS-3032b, an Oral MDM2 Inhibitor, in Subjects With Relapsed and/or Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Myeloma
Interventions: DRUG: DS-3032b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surface EMGdi Evaluate the Efficacy of Pulmonary Rehabilitation in Patients With COPD: a Multi Center Prospective Study
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DEVICE: Control group|DEVICE: Calibrated cycle ergometer|DEVICE: Threshold loading device|DEVICE: Calibrated cycle ergometer and threshold loading device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study To Assess The Safety, Parameters And Efficacy For Procedures Using A Radiofrequency Device
Status: COMPLETED
Conditions: Tissue Heating|Coagulation
Interventions: DEVICE: TempSure|DEVICE: Scalpel|DEVICE: Bovie|DEVICE: Pelleve
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Master Framework For Relapse or Refractory Acute Myeloid Leukemia
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia, in Relapse|Acute Myeloid Leukemia Refractory
Interventions: OTHER: Registration into the STREAM platform
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Traditional Chinese Medicine on Outcomes in Patients With Severe / Very Severe COPD
Status: UNKNOWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Salmeterol / fluticasone (Seretide®)|DRUG: Bufeijianpi granule|DRUG: Bufeiyishen granule|DRUG: Yiqizishen granule|DRUG: Placebo Bufeijianpi granule|DRUG: Placebo Bufeiyishen granule|DRUG: Placebo Yiqizishen granule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Boceprevir Treatment in Participants With Chronic Hepatitis C Genotype 1 Deemed Nonresponders to Peginterferon/Ribavirin (P05514)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Boceprevir|BIOLOGICAL: Peginterferon alfa-2b (SCH 54031)|DRUG: Ribavirin (SCH 18908)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnesium and Postoperative Pain
Status: TERMINATED
Conditions: Arthritis Knee|Magnesium Sulfate|Dexmedetomidine
Interventions: DRUG: Magnesium Sulfate|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Understand the Safety, Tolerability, and Activity of Drug in Body Over a Period of Time of AZD2693, in Subjects of Non-Childbearing Potential in Overweight But Otherwise Healthy Subjects, and Healthy Chinese and Japanese Subjects
Status: COMPLETED
Conditions: Metabolic Disorders|Non-alcoholic Steatohepatitis
Interventions: DRUG: AZD2693|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Tolerability, and Comfort of 0.3% Hypromellose Eyedrops in Patients Undergoing LASIK Surgery
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Pre-LASIK 0.3% hypromellose|DRUG: Post-LASIK 0.3% hypromellose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells
Status: RECRUITING
Conditions: Corneal Ulcer
Interventions: BIOLOGICAL: Mesenchymal Stromal Cells|OTHER: Control Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Bovine Carotid Artery Biologic Graft and Expanded Polytetrafluoroethylene for Permanent Hemodialysis Access
Status: TERMINATED
Conditions: End Stage Renal Disease|Hemolysis|Arteriovenous Graft
Interventions: DEVICE: Expanded polytetrafluoroethylene Graft|DEVICE: Bovine Carotid Artery Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Killed Oral Cholera Vaccine in Kolkata
Status: COMPLETED
Conditions: Diarrhea|Cholera|Vibrio Infections
Interventions: BIOLOGICAL: bivalent killed whole cell oral cholera vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adding Stewed Apricot Juice to Senna Improves the Right-Side and Overall Colon Cleansing Quality for Colonoscopy Preparation
Status: COMPLETED
Conditions: Colonoscopy Preparation
Interventions: DRUG: Senna and stewed apricot juice|DRUG: Senna alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Trekking Poles to Aid Multiple Sclerosis Gait Impairment
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: No device|DEVICE: Single-point cane (SPC)|DEVICE: Four-point cane (FPC)|DEVICE: Trekking pole (TP).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of TUDCA as add-on Treatment in Patients Affected by ALS
Status: ACTIVE_NOT_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: DRUG: Tauroursodeoxycholic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Effects in Patients With Refractory Non-Small Cell Lung Cancer Using FLT Positron Emission Tomography
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Non-Small Cell Lung Carcinoma|Stage IIIA Non-Small Cell Lung Cancer|Stage IIIB Non-Small Cell Lung Cancer|Stage IV Non-Small Cell Lung Cancer
Interventions: DRUG: Dexamethasone|DEVICE: Device for PET|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy Study of a New Treatment for Recurrent Symptoms of Oral Herpes Virus Infection
Status: COMPLETED
Conditions: Oral Herpes Simplex
Interventions: DRUG: BTL TML HSV|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Cetuximab in Combination With Cisplatin and Vinorelbine to Treat Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Neoplasms|Carcinoma|Cancer of the Lung|Non-Small-Cell Lung Carcinoma
Interventions: DRUG: Cetuximab|DRUG: Cisplatin|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome of Balloon Pulmonary Valvuloplasty in Patients With Congenital Pulmonary Stenosis in Terms of Reverse Right Ventricular Remodelling and Functional Exercise Capacity
Status: RECRUITING
Conditions: Congenital Heart Disease|Pulmonary Valve Stenoses
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nicotine and Sensorimotor Replacement for Smoking in Smokers With Schizophrenia
Status: COMPLETED
Conditions: Tobacco Use Disorder|Schizophrenia
Interventions: BEHAVIORAL: sensorimotor replacement|DRUG: 42 mg transdermal nicotine replacement|DRUG: Placebo transdermal nicotine|OTHER: usual brand smoking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: GIP and GLP-1 on Gastric Emptying, Appetite and Insulin-glucose
Status: COMPLETED
Conditions: Physiology|Gastroenterology|Endocrinology
Interventions: OTHER: Glucose-insulinotropic peptide, Glucagon-like peptide-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Patients Satisfaction of Attachment Retained Versus Clasp Retained Obturators in Unilateral Total Maxillectomy
Status: COMPLETED
Conditions: Tumour
Interventions: OTHER: attachment retained obturator|OTHER: clasp retained obturator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Integrating a Mental Health Intervention Into Primary Health Care for Refugees
Status: RECRUITING
Conditions: Medication Adherence|Mental Health Issue|Self Efficacy|Hypertension|Epilepsy|Diabetes
Interventions: BEHAVIORAL: Common Elements Treatment Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Inhaled N-Acetylcysteine Compared to Normal Saline on Sputum Rheology and Lung Function
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DRUG: Acetylcysteine|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Upper and Lower Airway Colonization in Cystic Fibrosis Patients After Lung Transplantation
Status: UNKNOWN
Conditions: Cystic Fibrosis|Lungtransplantation|Paranasal Sinus Diseases
Interventions: OTHER: Bronchoalveolar and Nasal Lavage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Reproductive Options in Inherited Skin Diseases
Status: ENROLLING_BY_INVITATION
Conditions: Ichthyosis|Palmoplantar Keratoses|Epidermolysis Bullosa|Ectodermal Dysplasia|Basal Cell Nevus Syndrome|Birt-Hogg-Dube Syndrome|Tuberous Sclerosis|Xeroderma Pigmentosum|Cutis Laxa|Albinism
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Tolerability Study of ALKS 8700 in Subjects With Relapsing Remitting Multiple Sclerosis (RRMS) EVOLVE-MS-2
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: ALKS 8700|DRUG: Dimethyl Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Moxifloxacin in Preventing Bacterial Infections in Patients Who Have Undergone Donor Stem Cell Transplant
Status: TERMINATED
Conditions: Breast Cancer|Chronic Myeloproliferative Disorders|Gestational Trophoblastic Tumor|Infection|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Neuroblastoma|Ovarian Cancer|Testicular Germ Cell Tumor
Interventions: DRUG: moxifloxacin hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Growth Response in Short Children Suffering From a Disease With Growth Retardation and Treated With Somatropin
Status: COMPLETED
Conditions: Idiopathic Short Stature
Interventions: DRUG: somatropin (Genotropin® treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality and Concept of Control in the Treatment of Acrophobia
Status: UNKNOWN
Conditions: Phobic Disorders
Interventions: BEHAVIORAL: Exposure to anxiogenous environments|OTHER: Imagery with functional MRI initial|OTHER: Imagery with PET-scanner initial|OTHER: Imagery with functional MRI final|OTHER: Imagery with PET-scanner final
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Enzalutamide in Patients With Nonmetastatic Castration-Resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Nonmetastatic Castration-Resistant Prostate Cancer|Prostate Cancer|Cancer of the Prostate
Interventions: DRUG: Enzalutamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of the Safety and Pharmacokinetics of GC4711 (Oral Capsule) Compared to GC4419 (IV Infusion) and GC4711 (IV Infusion) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: GC4711 Oral Capsule G-101|DRUG: IV GC4419|DRUG: GC4711 Oral Capsule G-101|DRUG: GC4711 Oral Capsule G-101|DRUG: GC4711 Oral Capsule G-111|DRUG: GC4711 Oral Capsule G-112|DRUG: GC4711 Oral Capsule G-119|DRUG: GC4711 Oral Capsule G-125|DRUG: IV GC4711
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Effects of Elranatamab (PF 06863135) Versus Standard of Care (SOC) in Patients With Multiple Myeloma (MM) in Germany and US
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Elranatamab|DRUG: Standard of Care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Validation of a Newly Developed Sham Press Needle
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Ring Sham (RS)|DEVICE: Real Needle (RN)|DEVICE: Kim Sham (KS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: An Efficacy and Safety Study of Transdermal Therapeutic System (TTS)-Fentanyl in Cancer Participants With Inadequately Controlled Pain by Non-Narcotic Analgesics
Status: COMPLETED
Conditions: Pain; Cancer
Interventions: DRUG: Fentanyl D-trans
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Continuous Femoral Block and Intravenous Parecoxib For Postoperative Analgesia After Total Knee Arthroplasty
Status: COMPLETED
Conditions: POSTOPERATIVE ANALGESIA FOR TKA PARECOXIB/CFB
Interventions: DRUG: Parecoxib|DRUG: CONTINUOUS FEMORAL BLOCK WITH ROPIVACAINE 0,2%|DRUG: N/S 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Sevoflurane Versus Desflurane for Catheter-related Bladder Discomfort
Status: COMPLETED
Conditions: Catheter Site Discomfort|Complications|Anesthesia|Urinary Bladder Neoplasms
Interventions: DRUG: Sevoflurane|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Efficacy of Different Time Interval Between rTMS and Rehabilitation Program for Motor Recovery in Stroke Patients
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: OTHER: rTMS-PTi|OTHER: rTMS-PTd|OTHER: rTMSs-PT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Delivering Contingency Management in Outpatient Addiction Treatment
Status: COMPLETED
Conditions: Methamphetamine|Methamphetamine Abuse|Methamphetamine-dependence|Contingency Management|Substance Use|Substance Abuse|Substance Use Disorders|Drug Use|Drug Abuse|Adults|Humans
Interventions: BEHAVIORAL: Contingency management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Buprenorphine Transdermal Patch (BTDS) in Osteoarthritis Pain: a 52-Week Extension Phase
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: DRUG: Buprenorphine transdermal patch|DRUG: Buprenorphine transdermal patch|DRUG: Buprenorphine transdermal patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction of Remission in RA Patients at Low Disease Activity by Additional Infliximab Therapy (Study P04644AM1) (TERMINATED)
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: infliximab|DRUG: DMARDs (methotrexate; chloroquine; leflunomidum; cyclosporin A; sulfasalazine; OM 89.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-Eluting Stents vs. Bare Metal Stents In Saphenous Vein Graft Angioplasty
Status: COMPLETED
Conditions: Saphenous Vein Graft Atherosclerosis
Interventions: DEVICE: Bare Metal Stent|DEVICE: Drug-Eluting Stent|DRUG: Blinded clopidogrel|DRUG: Placebo|DRUG: Thienopyridine (open-label)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Chinese Herbal Medicine for Reducing the Application of Antibiotics in the Treatment of Acute Mastitis
Status: UNKNOWN
Conditions: Mastitis Acute Female
Interventions: DRUG: CHPM (Chinese Herbal Patent Medicine )|DRUG: Antibiotics Cefdinir Capsules|BEHAVIORAL: Education|DRUG: Antibiotics Cefdinir Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opportunities for Antibiotic Optimisation and Outcomes Improvement in Patients With Negative Blood Culture (NO-BACT)
Status: COMPLETED
Conditions: Antibiotic Resistant Infection
Interventions: BEHAVIORAL: PROA for optimization|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Techniques for Abdominoplasty After Massive Weight Loss
Status: WITHDRAWN
Conditions: Skin; Excess
Interventions: PROCEDURE: Lipo-abdominoplasty|PROCEDURE: Abdominoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Post-Conditioning and Administration of Vitamin C on Intramuscular High Energy Phosphate Levels
Status: UNKNOWN
Conditions: Ischemia Reperfusion Injury
Interventions: DRUG: Vit C|PROCEDURE: Postconditioning|OTHER: no intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intradialytic Resistance Training in Haemodialysis Patients
Status: COMPLETED
Conditions: Chronic Kidney Disease Requiring Chronic Dialysis
Interventions: BEHAVIORAL: Intradialytic resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Power of Choice on Autonomy, Motivation, Exercise Adherence, and Cardiorespiratory Fitness
Status: ACTIVE_NOT_RECRUITING
Conditions: Elevated Blood Sugar
Interventions: BEHAVIORAL: MICT|BEHAVIORAL: HIIT|BEHAVIORAL: CHOICE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness and Tolerability of Fitostimoline Plus Cream and Gauze vs Connettivina Bio Plus Cream and Gauze
Status: UNKNOWN
Conditions: Wound Heal|Wound Infection|Wounds and Injuries
Interventions: DEVICE: fitostimoline plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of REOLYSIN® in Combination With FOLFIRI and Bevacizumab in FOLFIRI Naive Patients With KRAS Mutant Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: KRAS Mutant Metastatic Colorectal Cancer
Interventions: BIOLOGICAL: REOLYSIN®|DRUG: Irinotecan|DRUG: Leucovorin|DRUG: Fluorouracil (5-FU)|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Effectiveness and Safety Study Comparing Oxybutynin Chloride Plus FLOMAX (Tamsulosin HCl) and Placebo Plus FLOMAX (Tamsulosin HCl) for the Treatment of Lower Urinary Tract Symptoms.
Status: COMPLETED
Conditions: Urination Disorders
Interventions: DRUG: oxybutynin chloride extended release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study Of Natalizumab Plus Standard Steroid Treatment For High Risk Acute Graft-Versus-Host Disease
Status: COMPLETED
Conditions: Acute Graft Versus Host Disease
Interventions: DRUG: natalizumab|DRUG: steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes After Bilateral Implantation of ZEISS AT LISA TRI AND TRI TORIC IOL
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: AT LISA TRI TORIC|DEVICE: AT LISA TRI
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of SKLB1028 Capsule in the Treatment of Recurrence/Refractory AML Patients
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: SKLB1028 150mg bid|DRUG: SKLB1028 200mg bid|DRUG: SKLB1028 300mg qd
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PRT-201 Administered Immediately After Arteriovenous Fistula Creation in Patients With Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: PRT-201|DRUG: Placebo|DRUG: PRT-201
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enfortumab Vedotin and Pembrolizumab in People With Bladder Cancer
Status: RECRUITING
Conditions: Urothelial Carcinoma
Interventions: DRUG: Enfortumab vedotin|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pretreatment With Unfractionated Heparin for ST Elevation Myocardial Infarction
Status: RECRUITING
Conditions: STEMI - ST Elevation Myocardial Infarction
Interventions: DRUG: Unfractionated heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT