pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Double-Blind, Multi-Center, Randomized Study to Assess the Efficacy and Safety of Velneperit (S-2367) and Orlistat Administered Individually or Combined With a Reduced Calorie Diet (RCD) in Obese Subjects
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Velneperit 400 mg|DRUG: Orlistat 120 mg|DRUG: Orlistat Placebo|DRUG: Velneperit Placebo|OTHER: Reduced Calorie Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Oncological Safety and Cosmetic Outcome of Areola Sparing Mastectomy : a Single Arm, Prospective, Cohort Study
Status: RECRUITING
Conditions: Breast Neoplasms
Interventions: PROCEDURE: Areola Sparing Mastectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Soy Polysaccharide Fiber for the Treatment of Chronic Constipation in Children: a Randomized, Double-blind Trial
Status: COMPLETED
Conditions: Constipation
Interventions: DIETARY_SUPPLEMENT: Soy polysaccharide fiber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cannabinol Use in Patients With Insomnia Disorder
Status: COMPLETED
Conditions: Insomnia Disorder
Interventions: DRUG: 30 mg Cannabinol (CBN)|DRUG: 300 mg Cannabinol (CBN)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Response Effects of Cervical Spinal Manipulative Therapy (SMT) on Pressure Sensitivity of Myofascial Trigger Points
Status: COMPLETED
Conditions: Trigger Points, Myofascial|Myofascial Trigger Points|Myofascial Pain Syndrome
Interventions: OTHER: cervical spinal manipulative therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Escape Room Intervention to Help Improve Breast Cancer Patients' Ability to Navigate Online Access to Nutrition Information
Status: COMPLETED
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8
Interventions: OTHER: Educational Intervention|OTHER: Interview|OTHER: Survey Administration|OTHER: Telemedicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Laparoscopic Groin Hernia Repair by a 3D ENDOLAP Visible Mesh With or Without LiquiBand Fix 8 Mesh Fixation
Status: RECRUITING
Conditions: Hernia|Recurrence
Interventions: PROCEDURE: LiquiBand Fix8 glue fixation|PROCEDURE: No-fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of the New 20 mm Lumen Apposing Metal Stent (Lams) for Endoscopic Treatment of Pancreatic and Peripancreatic Fluid Collections
Status: COMPLETED
Conditions: Pancreatic Diseases
Interventions: DEVICE: Hot Axios stent
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase I Study of U3P1287/01, Including Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: U3-1287 (AMG888)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Carbohydrate and Internal Body Fat
Status: COMPLETED
Conditions: Adiposity
Interventions: BEHAVIORAL: Acellular carbohydrate diet|BEHAVIORAL: Cellular carbohydrate diet|BEHAVIORAL: Low-carbohydrate high-fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of BPI-21668
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: BPI-21668
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Addition of Oral Analgesics to LET During Laceration Repair
Status: SUSPENDED
Conditions: Laceration|Pain
Interventions: DRUG: Ibuprofen|DRUG: Oxycodone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Randomized, Double Blind, Placebo Controlled Study of AMG 386 in Combination With FOLFIRI in Subjects With Previously Treated Metastatic Colorectal Carcinoma
Status: COMPLETED
Conditions: Cancer|Carcinoma|Colon Cancer|Colorectal Cancer|Gastrointestinal Cancer|Metastases|Metastatic Cancer|Metastatic Colorectal Cancer|Oncology|Rectal Cancer
Interventions: DRUG: AMG 386|DRUG: AMG 386 Placebo|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Atropine During Ketamine Sedation
Status: COMPLETED
Conditions: Conscious Sedation
Interventions: DRUG: Atropine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Ailliance Post-Market Clinical Study
Status: RECRUITING
Conditions: Spinal Deformity|Spinal Degenerative Disorder|Spinal Fusion Failure|Spinal Trauma|Spinal Tumor Case
Interventions: DEVICE: Follow-up schedule: pre-operative baseline to index surgery|DEVICE: Follow-up schedule: pre-operative baseline to discharge|DEVICE: Follow-up schedule: pre-operative baseline up to 24-months post-procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bangladesh MSNP: Social Protection Mixed Methods Study
Status: WITHDRAWN
Conditions: Stunting|Undernutrition
Interventions: OTHER: Control|OTHER: Strengthened (Services and SBCC)|OTHER: Strengthened (Services and SBCC) + CCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Nivolumab in Combination With Ipilimumab Compared to the Standard of Care (Extreme Regimen) as First Line Treatment in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab|DRUG: Cetuximab/Erbitux|DRUG: Cisplatin/Platinol|DRUG: Carboplatin/Paraplatin|DRUG: Fluorouracil/Adrucil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of EgyVax Vaccine Candidate for Prophylaxis of COVID-19 Infection
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: EgyVax Vaccine Candidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nutritional Supplements on Blood Pressure 2008
Status: UNKNOWN
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: NanoGreens|DIETARY_SUPPLEMENT: Whey protein|DIETARY_SUPPLEMENT: Calcium pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quantification of Immune Cells in Women Using Contraception (CHIC II)
Status: COMPLETED
Conditions: HIV|Immune Cells (Mucosal and Systemic)|Contraception
Interventions: DRUG: levonorgestrel exposure|DRUG: DMPA exposure|DRUG: etonogestrel exposure|DEVICE: IUD insertion|DEVICE: subdermal contraceptive implant insertion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Three Fibres on Glycaemic and Insulinaemic Responses in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Experimental Dietary Fibre 1|DIETARY_SUPPLEMENT: Experimental Dietary Fibre 2|DIETARY_SUPPLEMENT: Polydextrose|DIETARY_SUPPLEMENT: Dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: A Non-Interventional Pilot Study to Explore the Role of Gut Flora in IBS
Status: UNKNOWN
Conditions: Irritable Bowel|Irritable Bowel Syndrome|Irritable Bowel Syndrome With Diarrhea|Irritable Bowel Syndrome Mixed|Irritable Bowel Syndrome With Constipation|Irritable Bowel Syndrome Without Diarrhea|Irritable Bowel Syndrome Aggravated|Irritable Bowel Syndrome Characterized by Constipation|Irritable Bowel Syndrome Characterised by Alternating Bowel Habit
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Docetaxel, Capecitabine, Cisplatin, and Bevacizumab in Patients With Unresectable Advanced Gastric Cancer
Status: COMPLETED
Conditions: Advanced Gastric Cancer
Interventions: DRUG: Docetaxel, Capecitabine, Cisplatin, Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: My Care My Call: Peer-Led Health Empowerment Training in Chronic Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: BEHAVIORAL: Calls from a Peer Health Coach for 6 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability of Cannabidiol Among Persons With Opioid Use Disorder Receiving Methadone or Buprenorphine
Status: COMPLETED
Conditions: Addiction
Interventions: DRUG: CBD Day 1|DRUG: CBD Day 2|DRUG: CBD Day 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Evaluation of a Cognitive Rehabilitation Program for Persons With Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis|Cognitive Impairment
Interventions: BEHAVIORAL: Self-management cognitive rehabilitation group intervention|BEHAVIORAL: Control intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Identification and Dynamics With Cerebral Functional Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: cerebral fMRI|OTHER: cerebral fMRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pilot Study to Evaluate the Pharmacokinetics of Omega-3 Between Rosuvastatin and Omega-3 Coadministration and HCP1007
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HCP1007|DRUG: Omarco and Crestor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shock Energy for Electrical Cardioversion of Persistent Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: 360J LifePak Monitor/Defibrillator|DEVICE: 200J Philips HeartStart MRx Monitor/Defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Advancing Suicide Intervention Strategies for Teens During High Risk Periods
Status: RECRUITING
Conditions: Suicide Attempts|Suicidal Ideation|Suicide and Self-harm|Suicide Threat
Interventions: BEHAVIORAL: Safety Planning Intervention+ (SPI+)|BEHAVIORAL: Collaborative Assessment and Management of Suicidality (CAMS)|BEHAVIORAL: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety Confirmation Between FASTSEAL® Bioabsorbable VCD and Perclose® ProGlide SMC System
Status: TERMINATED
Conditions: The Patients Who Needed Hemostasis at the Puncture Site of Common Femoral Artety(CFA) Caused by Femoral Angiogram or Intervention After the Catheter Removal
Interventions: DEVICE: Vascular Closure Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Individualized Vancomycin Dosing Based on Population PK Model
Status: RECRUITING
Conditions: Severe Infection
Interventions: DRUG: individualized vancomycin dosing based on the population pharmacokinetics (PK) model|DRUG: empirical vancomycin dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: mFOLFOX Versus mFOLFIRI Versus FOLFPTX as First-line Treatment in AGC or EGJA
Status: UNKNOWN
Conditions: Advanced Gastric Cancer Adenocarcinoma of Esophagogastric Junction
Interventions: DRUG: Fluorouracil|DRUG: Oxaliplatin|DRUG: Irinotecan|DRUG: Paclitaxel|DRUG: calcium levofolinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT to Assess the Clinical Benefit of the ERA Test in Infertile Women at Their First IVF/ICSI Cycle
Status: UNKNOWN
Conditions: Infertility, Female|IVF/ICSI
Interventions: DIAGNOSTIC_TEST: ERA|DIAGNOSTIC_TEST: ERA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Investigate Safety and Tolerability of mRNA-0184 Administered at 2 Different Infusion Durations in Healthy Participants
Status: RECRUITING
Conditions: Healthy Participants
Interventions: DRUG: mRNA-0184
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combining EPI-7386 With Enzalutamide and Androgen Deprivation Therapy for Metastatic Hormone-Sensitive Prostate Cancer
Status: RECRUITING
Conditions: Metastatic Hormone-sensitive Prostate Cancer (mHSPC)|Prostate Cancer|Prostate Adenocarcinoma
Interventions: DRUG: EPI-7386|DRUG: Enzalutamide|DRUG: Androgen Deprivation Therapy (ADT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Therapeutic Exercise in Acute Respiratory Failure to Improve Neuromuscular Disability Trial
Status: COMPLETED
Conditions: Critical Illness|Acute Respiratory Failure
Interventions: BEHAVIORAL: Early mobilization intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Treatment With Human Umbilical Cord-derived Mesenchymal Stem Cells for Decompensated Cirrhosis
Status: UNKNOWN
Conditions: Decompensated Cirrhosis
Interventions: BIOLOGICAL: UC-MSCs|BIOLOGICAL: Saline containing 1% Human serum albumin（solution without UC-MSCs）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Volleyball Intervention on Health-related Fitness in Primary School Students
Status: COMPLETED
Conditions: Physical Inactivity|Adolescent Obesity|Physical Fitness|Body Composition|Healthy Lifestyle|Exercise
Interventions: OTHER: TGfU volleyball intervention|OTHER: Regular physical education classes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Faropenem and Cefadroxil (in Combination With Amoxicillin/Clavulanic Acid and Standard TB Drugs) in Patients With Pulmonary Tuberculosis: Measurement of Early Bactericidal Activity and Effects on Novel Biomarkers
Status: COMPLETED
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: Faropenem|DRUG: Amoxicillin/clavulanic acid|DRUG: Cefadroxil|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of CYT-108, a Recombinant Protease Inhibitor, for Treatment of Mild to Moderate Primary Osteoarthritis of the Knee
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee|Osteoarthritis
Interventions: BIOLOGICAL: CYT-108, a recombinant protease inhibitor|OTHER: Phosphate Buffered Saline (PBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Probiotics and Fibers on Albuminuria in Persons With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes|Nephropathy|Albuminuria|Diabetic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: Pro-/prebiotic Mix|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Home Exercise Intervention on Bone Density, Muscle Functions, QoL, and Curve Progression in Girls With AIS
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of the CiTop™ ExPander™ Guidewire for Crossing Chronic Total Occlusions in Coronary Arteries
Status: TERMINATED
Conditions: Coronary Chronic Total Occlusion
Interventions: DEVICE: CiTop™ ExPander™ Guidewire
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tai Chi on Symptoms in Hemodialysis Patients
Status: NOT_YET_RECRUITING
Conditions: Dialysis; Complications|Chinese Medicine|Quality of Life
Interventions: BEHAVIORAL: Tai chi|BEHAVIORAL: Tai Chi imagery|OTHER: no-intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pilot Study on the Effects of FSH Treatment on the Epigenetic Characteristics of Spermatozoa in Infertile Patients With Severe Oligozoospermia
Status: TERMINATED
Conditions: Male Infertility
Interventions: DRUG: Bravelle
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Posterior Indirect Adhesive Restorations
Status: UNKNOWN
Conditions: Dental Caries|Endodontically Treated Teeth|Dental Restoration Failure of Marginal Integrity|Wear, Occlusal|Indirect Posterior Restoration
Interventions: DEVICE: Indirect adhesive restoration of posterior teeth
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anamorelin Study for Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Anamorelin Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Is Combined Steroid and Sodium Hyaluronate Hydrodilatation More Effective Than Isolated Steroid Hydrodilatation in Treating Patients With Adhesive Capsulitis
Status: RECRUITING
Conditions: Adhesive Capsulitis
Interventions: DRUG: normal saline|DRUG: (Sodium Hyaluronate (Hyruan One , LG)|DRUG: lidocaine hydrochloride|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Distributed Registry
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Intermittent Claudication|Arteriosclerosis|Atherosclerosis|Arterial Occlusive Diseases|Vascular Diseases|Cardiovascular Diseases|Peripheral Vascular Diseases|Signs and Symptoms|Patient Compliance
Interventions: BEHAVIORAL: Patient reported outcomes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: mDiet - Ecological Momentary Intervention of Diet Via Mobile Technology
Status: COMPLETED
Conditions: Overweight
Interventions: BEHAVIORAL: Printed Material|BEHAVIORAL: Weekly Weighing|BEHAVIORAL: Cell phone will serve as a self monitoring device|DEVICE: Text Message|BEHAVIORAL: Diet Goals via Cell Phone|BEHAVIORAL: Food Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of TENS for Pain and Function After Total Knee Replacement
Status: COMPLETED
Conditions: Unilateral Primary Osteoarthritis of Knee|Primary Osteoarthritis of Knee Nos
Interventions: DEVICE: Placebo TENS|DEVICE: Active TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Nebulized Budesonide on Preventing Postextubation Complications in Critically Patients
Status: UNKNOWN
Conditions: Respiratory Sounds
Interventions: DRUG: Budesonide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Regorafenib in Combination With Paclitaxel in Advanced Oesophagogastric Carcinoma
Status: COMPLETED
Conditions: Esophageal Neoplasms|Stomach Neoplasms|Neoplasm Metastasis
Interventions: DRUG: Regorafenib|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lomitapide in Paediatric Patients With Homozygous Familial Hypercholesterolaemia (HoFH)
Status: COMPLETED
Conditions: Homozygous Familial Hypercholesterolaemia (HoFH)
Interventions: DRUG: Lomitapide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endo-nasal Endoscopic DCR and External-DCR in Primary Nasolacrimal Duct Obstruction
Status: UNKNOWN
Conditions: Primary Acquired Nasolacrimal
Interventions: PROCEDURE: Endoscopic DCR|PROCEDURE: External DCR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study That Will Assess the Effect of SEP-363856 and Prior Antipsychotic (PA) Standard of Care on Glucose and Regulation of Insulin in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: SEP-363856
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Daclatasvir (BMS-790052) Plus Standard of Care (Pegylated-interferon Alpha and Ribavirin)
Status: COMPLETED
Conditions: Hepatitis C Infection
Interventions: DRUG: Daclatasvir|DRUG: Daclatasvir|DRUG: Daclatasvir|DRUG: Placebo|DRUG: Peginterferon alpha-2a|DRUG: ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-pharmacological Care of Alzheimer's Disease: Benefice of Musical Interventions
Status: COMPLETED
Conditions: Alzheimer's Disease (AD) and Related Disorders
Interventions: BEHAVIORAL: Musical intervention|BEHAVIORAL: Non-musical (cooking) intervention|BEHAVIORAL: Control with no intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Dosing Procedures of Chemotherapy Treatment (Carboplatin) With the Contrast Agent Iohexol
Status: RECRUITING
Conditions: Malignant Solid Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Carboplatin|DRUG: Iohexol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided H-FICB for Arthroscopic Knee Surgery： What is the Optimal Dose of Dexmedetomidine?
Status: COMPLETED
Conditions: Knee Disease|Quality of Recovery
Interventions: PROCEDURE: ultrasound-guided high fascia iliaca compartment block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Sublingual Film for the Management of Agitation in Delirium: Safety and Preliminary Efficacy
Status: WITHDRAWN
Conditions: Delirium
Interventions: DRUG: Dexmedetomidine sublingual film
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Kidney Transplant Subjects to Investigate the Optimal Suppression of Immunity to Help Prevent Kidney Rejection
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Prograf®|DRUG: Advagraf®|DRUG: Mycophenolate Mofetil|DRUG: Simulect|DRUG: methylprednisolone / prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase I Study in Healthy Volunteers to Assess the Effect of Cytochrome3A4 (CYP3A4) Inhibitors (Diltiazem and Itraconazole) on the Pharmacokinetics (PK) of AZD3293 and the Effects of AZD3293 on the Pharmacokinetics of Midazolam, a Cytochrome 3A4 and Cytochrome 3A5 (CYP3A4/CYP3A5) Substrate
Status: COMPLETED
Conditions: Healthy Volunteers|Pharmacologic Action
Interventions: DRUG: Group 1 AZD3293|DRUG: Group 2 AZD3293|DRUG: Group 3 AZD3293|DRUG: Group 1 Itraconazole|DRUG: Group 2 Diltiazem|DRUG: Group 3 Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multidisciplinary Program "Optimization of Drug Prescription" : Impact on the Quality of Drug Prescription in Hospitalized Elderly Patients
Status: COMPLETED
Conditions: Potentially Inappropriate Medications
Interventions: OTHER: " Optimisation de la Prescription MEDicamenteuse " ("Optimization of drug prescribing")
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Prospective Study Comparing Urgent Video Capsule Endoscopy With Urgent Double-balloon Enteroscopy
Status: COMPLETED
Conditions: Overt Obscure Gastrointestinal Bleeding
Interventions: DEVICE: video capsule endoscopy|DEVICE: double balloon enteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regorafenib+FOLFIRI Versus Placebo+FOLFIRI as 2nd Line Tx in Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Regorafenib (BAY 73-4506)|DRUG: FOLFIRI|DRUG: Placebo|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Fostamatinib Monotherapy Compared With Adalimumab Monotherapy in Patients With Rheumatoid Arthritis (RA)
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Fostamatinib and placebo injections|DRUG: Fostamatinib and placebo injections|DRUG: Fostamatinib and placebo injections|DRUG: Adalimumab and placebo of fostamatinib|DRUG: Placebo of fostamatinib, fostamatinib, and placebo injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dynamic MRI of the Behaviour of Female Pelvic Floor
Status: COMPLETED
Conditions: Stress Urinary Incontinence|Genital Prolapse
Interventions: PROCEDURE: movement of midurethra, bladder neck, cervix and rectum
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Proposal for a New Classification of Secondary Cleft Lip and Nose Deformities in Repaired Unilateral Cleft Lip
Status: COMPLETED
Conditions: Patients With Unilateral Cleft Lip With or Without Cleft Palate
Interventions: OTHER: Patients with Unilateral Cleft Lip with or without Cleft Palate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Proximal Stabilization on Recruitment of the Core & Vasti in Patellofemoral Arthritis During Descending Stairs
Status: COMPLETED
Conditions: Chondromalacia Patellae
Interventions: OTHER: traditional knee rehabilitation program|OTHER: proximal stabilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Efficacy and Safety of TG-C in Subjects With Kellgren/Lawrence Grade 2 or 3 OA of the Knee
Status: ACTIVE_NOT_RECRUITING
Conditions: Degenerative Osteoarthritis
Interventions: BIOLOGICAL: TG-C|BIOLOGICAL: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess the Safety, Tolerability and Immunogenicity of Repevax and rLP2086 Vaccine When Given Together in Healthy Subjects Aged >=11 to <19 Years.
Status: COMPLETED
Conditions: Meningococcal Vaccine|rLP2086|Repevax|N Meningitidis Serogroup B|Meningitis
Interventions: BIOLOGICAL: rLP2086|BIOLOGICAL: Repevax|BIOLOGICAL: Saline|BIOLOGICAL: Repevax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Dental Implant Healing With TNF-Alpha Inhibitors
Status: NOT_YET_RECRUITING
Conditions: Edentulism|Dental Implants|TNF-alpha Inhibitors
Interventions: PROCEDURE: Placement of dental implants
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Norepinephrine in Caesarian Section
Status: RECRUITING
Conditions: Cesarean Section Complications|Hemodynamic Instability|Foetal Stress
Interventions: DRUG: Norepinephrine|DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Gantenerumab in Participants With Early Alzheimer's Disease (AD)
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DRUG: Gantenerumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioavailability of Azithromycin 600 mg Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Infection
Interventions: DRUG: Azithromycin Monohydrate 600 mg Tablets|DRUG: Zithromax (azithromycin dihydrate) 600 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on Nutrition Intervention in Patients With Esophageal and Gastric Cancer Treated With Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Nutrition Aspect of Cancer
Interventions: DIETARY_SUPPLEMENT: Nutritional counseling，Enteral Nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Investigator-Initiated Study to Assess the Cooling Effect of Triamcinolone Acetonide Aerosol When Used for Steroid-Responsive Dermatoses
Status: COMPLETED
Conditions: Acute Steroid Responsive Dermatoses|Chronic Steroid Responsive Dermatoses
Interventions: DRUG: Triamcinolone Acetonide spray|DRUG: Triamcinolone acetonide cream|DRUG: Alcohol spray
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study About the Response to the Administration of a Third Dose of mRNA-1273 Vaccine (COVID-19 Vaccine Moderna) in Renal Transplants With Immunological Failure Initial to Vaccination
Status: WITHDRAWN
Conditions: Covid19
Interventions: DRUG: MRNA-1273
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Drug-drug Interactions (DDIs) of SKLB1028 With Itraconazole, Gemfibrozil or Rifampicin in Healthy Subjects
Status: UNKNOWN
Conditions: Healthy Subjects
Interventions: DRUG: SKLB1028|DRUG: Itraconazole|DRUG: Gemfibrozil|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity Study of Wockhardt's Insulin Lispro/Lispro Mix Basal Bolus Regimen in Type 1 Diabetics
Status: WITHDRAWN
Conditions: Type I Diabetes
Interventions: BIOLOGICAL: Insulin Lispro|BIOLOGICAL: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Recovered Covid 19 Plasma Transfusion to Covid 19 Severly Ill Patients
Status: UNKNOWN
Conditions: Covid19
Interventions: BIOLOGICAL: recovered covid 19 patients plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Characteristics of GLH1SM Extended Release Tablets in Healthy Volunteers(Fed)
Status: COMPLETED
Conditions: Healthy
Interventions: COMBINATION_PRODUCT: Janumet XR tablet 100/1000 mg|COMBINATION_PRODUCT: GLH1SM tablet 100/1000 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Core Training on Physical Fitness and Smash Performance Among Female Badminton Players in Guangxi, China
Status: NOT_YET_RECRUITING
Conditions: Athletes
Interventions: OTHER: Core straining
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bone Marrow-derived Mesenchymal Stem Cells (MSC) Administration in Weaning From Left Ventricular Assist Device
Status: WITHDRAWN
Conditions: Chronic Myocardial Ischemia
Interventions: DRUG: Autologous mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety, Tolerability, and Pharmacodynamics of MK-8931 in Participants With Alzheimer's Disease (MK-8931-010 AM1 [P07820 AM1])
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: MK-8931|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Home-based Balance Training Using Wii Fit After Stroke: A Feasibility Study
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: HBE Wii (EG)|OTHER: HBE Control (CG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Obstructive Sleep Apnea Operations on the Swallowing Function
Status: UNKNOWN
Conditions: Dysphagia|Sleep Apnea, Obstructive
Interventions: DEVICE: FEES|DIAGNOSTIC_TEST: SDQ|BEHAVIORAL: data review
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Warm Water Footbaths With Added Ginger or Mustard Powder on Psychosocial Parameters in Patients With an Oncological Disease
Status: COMPLETED
Conditions: Oncologic Disorders
Interventions: OTHER: Ginger powder footbaths|OTHER: Mustard powder footbaths|OTHER: Warm water only footbaths
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of TP-04 in Participants With Papulopustular Rosacea
Status: COMPLETED
Conditions: Papulopustular Rosacea
Interventions: DRUG: Lotilaner Gel, 2.0%|OTHER: Vehicle control gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determination of Glycaemic Index and Insulinaemic Index Values of 6 Food Products in 3 Separate Research Centers
Status: COMPLETED
Conditions: Glycaemia|Insulinemia
Interventions: OTHER: Reference Glucose|OTHER: Food Product A: Corn Flakes|OTHER: Food Product B: Ginger Bread|OTHER: Food Product C:Sandwiched Breakfast Biscuit|OTHER: Food Product D: Crackers Nature|OTHER: Food Product E: Breakfast Biscuit|OTHER: Food Product F: White Bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Disitamab Vedotin + Pyrotinib Versus THP in the First-line Treatment for HER2+ Advanced Breast Cancer Clinical Trial
Status: RECRUITING
Conditions: HER2-positive Metastatic Breast Cancer|First-line Treatment
Interventions: DRUG: disitamab vedotin|DRUG: Pyrotinib|DRUG: trastuzumab|DRUG: Pertuzumab|DRUG: taxane drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Measurement of Central Hemodynamics by Electrical Impedance Tomography
Status: WITHDRAWN
Conditions: Comparison of Availability for Prediction of Volume Responsiveness|Comparison of Limits of Agreement for Invasive and Non-invasive Measurement of Stroke Volume Variation
Interventions: OTHER: volume loading
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bandebereho 6 Year Follow up RCT in Rwanda
Status: COMPLETED
Conditions: Gender Relations|Violence|Child Development|Contraception|Prenatal Care|Partner Communication
Interventions: BEHAVIORAL: MenCare+/Bandebereho fathers'/couples' group education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Artificial Intelligence in Large-scale Breast Cancer Screening
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Neoplasm Female
Interventions: DIAGNOSTIC_TEST: AI CAD|DIAGNOSTIC_TEST: Radiologist reading
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of the Concentrations of Besifloxacin, Moxifloxacin, or Gatifloxacin in the Aqueous Humor of Subjects
Status: COMPLETED
Conditions: Cataract Extraction
Interventions: DRUG: Besifloxacin hydrochloride|DRUG: moxifloxacin hydrochloride|DRUG: gatifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Immunogenicity and Safety of Pentaxim as 3 Doses Primary Vaccination Followed by a Booster Dose at 18 Months
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Haemophilus Influenzae Type b|Pertussis|Poliomyelitis
Interventions: BIOLOGICAL: Diphtheria, Tetanus, Polio, Acellular Pertussis and Hib|BIOLOGICAL: Diphtheria, Tetanus, Polio, Acellular Pertussis and Hib|BIOLOGICAL: Diphtheria, Tetanus, & Acellular Pertussis Combined, Absorbed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sensory Nociceptive Nerve Fibers, Key Regulator of Immune Response Type 2 in Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: OTHER: Clinical examination|PROCEDURE: Biopsies|OTHER: Blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pudendal Nerve Block for Catheter-related Bladder Discomfort Prevention
Status: UNKNOWN
Conditions: Catheter Site Discomfort
Interventions: PROCEDURE: Bilateral pudendal nerve block|DRUG: Intravenous tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Pharmacokinetics of SAR245409 Tablets in Patients With Solid Tumors or Lymphoma
Status: COMPLETED
Conditions: Neoplasm Malignant
Interventions: DRUG: SAR245409
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Is Clarithromycin a Potential Treatment for Cachexia in People With Lung Cancer?
Status: TERMINATED
Conditions: Cachexia|Lung Cancer
Interventions: DRUG: Clarithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 3D Printed Personalized Ostomy Appliance
Status: NOT_YET_RECRUITING
Conditions: 3D Printing|Ostomy|Leakage
Interventions: DEVICE: 3D Printed Personalized Ostomy Appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CLDN18.2 Targeting PET Imaging in Patients With Gastrointestinal Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastrointestinal Cancer
Interventions: OTHER: 124I-18B10(10L) PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Research Study to Look at How Well Semaglutide Works in People Living With Heart Failure, Obesity and Type 2 Diabetes
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction (HFpEF) and Diabetes Mellitus, Type 2
Interventions: DRUG: Semaglutide|DRUG: Placebo (Semaglutide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Addressing Unmet Basic Needs to Improve Adherence Among Women With an Abnormal Pap
Status: COMPLETED
Conditions: Abnormal Pap Smear|Colposcopy
Interventions: OTHER: Basic needs survey|BEHAVIORAL: Life Navigator|OTHER: Follow-up survey|OTHER: Follow-up survey (phase II participants only)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Study on the Prevention of Surgical Wound Complications for Aneurysmal Thoracic-abdominal Aortic Pathology Using the "PREVENA" System
Status: COMPLETED
Conditions: Toraco Abdominal Aneurysm
Interventions: DEVICE: Sistema Prevena ™(TVAC)|OTHER: Standard medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Adapted Cognitive Behavioral Treatment for Depression in Patients With Moderate to Severe Traumatic Brain Injury
Status: COMPLETED
Conditions: Major Depressive Disorder|Traumatic Brain Injury
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for individuals with TBI|OTHER: Waitlist Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nattokinase Supplementation and Hemostatic Factors
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Nattokinase|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DIStal Versus COnventional RADIAL Access for Coronary Angiography and Intervention
Status: COMPLETED
Conditions: Coronary Disease
Interventions: PROCEDURE: Coronary angiography and or Percutaneous coronary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Thulium Fiber Laser Enucleation of the Prostate (ThuFLEP): Efficacy and Safety
Status: UNKNOWN
Conditions: Prostatic Hyperplasia
Interventions: PROCEDURE: Thulium Fiber Laser Enucleation of the Prostate|DEVICE: Thulium Fiber Laser "Urolase"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Crassostrea Gigas for Liver Health
Status: UNKNOWN
Conditions: Nonalcoholic Fatty Liver
Interventions: DIETARY_SUPPLEMENT: Hydrolyzed oyster extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BG00012 Monotherapy Safety and Efficacy Extension Study in Multiple Sclerosis (MS)
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: dimethyl fumarate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: rTMS for Depressed Teens: A Sham-Controlled Trial, Part 1
Status: TERMINATED
Conditions: Major Depressive Disorder
Interventions: DEVICE: Repetitive transcranial magnetic stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT