pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of tDCS on Motor Learning and Neural Network in Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Transcranial Direct Current Stimulation|BEHAVIORAL: Motor learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aqualase Versus Torsional ip. A Study on Endothelial Cells, Corneal Edema and Corneal Sensitivity
Status: COMPLETED
Conditions: Cataract
Interventions: PROCEDURE: liquefaction|PROCEDURE: Torsional ip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: iSTART: A Campus & Community Initiative for Services in Tec-health
Status: COMPLETED
Conditions: Substance Use|Binge Drinking|Marijuana Use|Alcohol Drinking|Prescription Opioid Misuse|Illicit Drug Use
Interventions: BEHAVIORAL: iSTART Web-app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of HPV Vaccine on Menstrual Cycle in Women of Reproductive Age
Status: RECRUITING
Conditions: Menstrual Disorder|Premature Ovarian Failure
Interventions: BIOLOGICAL: prophylactic HPV vaccine(bivalent HPV、quadrivalent HPV、9-valent HPV)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multiple Dose Healthy Volunteer Study of PF-03715455.
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: PF-03715455|DRUG: PF-03715455|DRUG: PF-03715455|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children
Status: RECRUITING
Conditions: Focal Segmental Glomerulosclerosis
Interventions: DEVICE: LIPOSORBER® LA-15 System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on Suicidality, Psychosis or Substance Abuse With Methylphenidate, Atomoxetine, Amphetamine/Dextroamphetamine or Lisdexamfetamine
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Methylphenidate|DRUG: Lisdexamfetamine|DRUG: Atomoxetine|DRUG: Amphetamine|DRUG: Dextroamphetamine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EUS-guided Entero-biliary Anastomosis for Therapeutic Access in Benign Biliary Obstructions
Status: RECRUITING
Conditions: Cholangiopancreatography, Endoscopic Retrograde
Interventions: PROCEDURE: EUS-guided Entero-biliary Anastomosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MENDiP: Measurements of Overnight Penile Temperature to Evaluate Nocturnal Erection Detection in Patients With Absence of Erectile Functioning After Robot-assisted Radical Prostatectomy
Status: NOT_YET_RECRUITING
Conditions: Erectile Dysfunction|Erectile Dysfunction Following Radical Prostatectomy
Interventions: DIAGNOSTIC_TEST: Feeling Hot sensor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial to Collect Safety Data and Sera for Immunogenicity Testing
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza Virus Vaccine (Fluzone®)|BIOLOGICAL: Influenza Virus Vaccine (Fluzone®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Oral Menthol on the Swallow Response of Patients With Oropharyngeal Dysphagia Associated With Neurological Diseases and Aging
Status: COMPLETED
Conditions: Deglutition Disorders
Interventions: DIETARY_SUPPLEMENT: menthol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Human Milk Fortification in Extremely Preterm Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Necrotizing Enterocolitis|Sepsis|Mortality
Interventions: DIETARY_SUPPLEMENT: H2MF|DIETARY_SUPPLEMENT: Bovine milk-based fortifier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The State of Play in Picardy of the Knowledge of the Elderly at Risk of Falling at Home in Terms of Prevention and Evaluation.
Status: COMPLETED
Conditions: Knowledge, Attitudes, Practice|Elderly
Interventions: OTHER: Assess the state of knowledge of the subjects falling or at risk, their risk of recurrence or first episode, compared to medical knowledge.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: S1803, Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: Daratumumab/rHuPH20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Dietary Treatment of Obese Adults
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: BEHAVIORAL: Standard dietary treatment (STD)|BEHAVIORAL: "Ned i vaegt" (NIV)|BEHAVIORAL: "Verdens bedste kur" (VBK)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Crystallized Phenol Versus Transposition Flaps for Treatment of Pilonidal Disease: A Prospective Study
Status: UNKNOWN
Conditions: Pilonidal Sinus
Interventions: DRUG: Crystallized phenol|PROCEDURE: Limberg Flap|PROCEDURE: Modified Limberg Flap|PROCEDURE: Karydakis Flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of Short Course Radiation Therapy Followed by Neoadjuvant Chemotherapy and Surgery in Locally Advanced Rectal Cancer
Status: COMPLETED
Conditions: Locally Advanced Rectal Carcinoma
Interventions: RADIATION: short course radiation therapy followed by 6 cycles of CAPOX then surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficiency of Game-Based Exercise Program and Trunk Stabilization Exercise Training in Adolescent Playing Archery
Status: COMPLETED
Conditions: Athlete; Itch
Interventions: OTHER: Trunk Stabilization Exercise Training Group|OTHER: Game Based Exercise Program Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasya in Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DEVICE: Nasya|DEVICE: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Critically Ill ICU Patients Under Casirivimab- and/or Tocilizumab Application
Status: COMPLETED
Conditions: COVID-19|Outcome, Fatal|Tocilizumab|Interleukin 6|Critically Ill
Interventions: DRUG: treated without (N), with casirivimab / imdevimab (C) or tocilizumab (T), solely, or in combination of both (C + T)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PROPHESSOR: AmBisome in Antifungal Primary Prophylaxis Treatment of High Risk Patients Undergoing Allogeneic Stem Cell Transplantation
Status: COMPLETED
Conditions: Fungus Diseases
Interventions: DRUG: AmBisome
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Piroxicam-beta-Cyclodextrin on Tooth Sensitivity Caused by In-office Bleaching
Status: COMPLETED
Conditions: Tooth Sensitivity|Toothache
Interventions: DRUG: Piroxicam-Beta-Cyclodextrin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect on Postoperative Sore Throat of Lidocaine Jelly Application Over the Endotracheal Tube of Tapered-shaped Cuff
Status: UNKNOWN
Conditions: Sore Throat
Interventions: DRUG: Lidocaine jelly application|DRUG: Normal saline application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Thigh Cuffs to Prevent the Deconditioning Induced by 5 Days of Dry Immersion
Status: COMPLETED
Conditions: Weightlessness|Weightlessness; Adverse Effect
Interventions: OTHER: Dry immersion Control Group|OTHER: Thigh cuffs intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety Study of Intravenous Ertapenem in Combination With Zidebactam (WCK 6777)
Status: COMPLETED
Conditions: Bacterial Infection
Interventions: DRUG: Ertapenem|OTHER: Placebo|DRUG: WCK 6777|DRUG: Zidebactam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of Kalinox® 170 Bar for the Performance of Care Procedures in Children With Burns
Status: WITHDRAWN
Conditions: Burns
Interventions: DRUG: 50% Oxygen/50% Nitrous oxide premix (KALINOX 170 bar)|DRUG: 50%Oxygen/50% Nitrogen premix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-inflammatory Effects of Intracoronary and Intravenous Abciximab Administration During Primary Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Intracoronary administration of an abciximab bolus during primary PCI|DRUG: Intravenous administration of an abciximab bolus during primary PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of SPD485 in Children Aged 6-12 Diagnosed With ADHD and Previously Participated in MTS Trials
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Methylphenidate Transdermal System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Endodontic Treatment Techniques in Postoperative Symptoms, Apical Repair, Longevity of Rehabilitations, and Oral Health-related Quality of Life
Status: UNKNOWN
Conditions: Endodontically Treated Teeth|Postoperative Pain|Edema|Photochemotherapy
Interventions: OTHER: Foraminal Enlargement / Irrigating solutions / Filling materials|OTHER: Photobiomodulation|OTHER: Passive ultrasonic irrigation|OTHER: OHIP-14|OTHER: Assessment of pain and edema|OTHER: Assessment of periapical lesion|OTHER: Longevity of rehabilitations|OTHER: Cryotherapy|OTHER: Ozone therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: We-PAP: A Couples-based Intervention for Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: BEHAVIORAL: Couples-based treatment|OTHER: Standardized education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects and Safety of Liposome Encapsulated Botulinum Toxin A for Overactive Bladder Syndrome
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Liposome encapsulated botulinum toxin A|DRUG: Normal saline instillation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Demonstrate the Clinical Accuracy of the Smartphone Vital Signs System (SVSS)
Status: WITHDRAWN
Conditions: Healthy Volunteers
Interventions: DEVICE: SVSS and reference devices|DEVICE: SVSS and reference devices|DEVICE: SVSS and reference devices|DEVICE: SVSS and reference devices
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of ACE-041 in Patients With Advanced Solid Tumors or Relapsed/Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Advanced Solid Tumors|Multiple Myeloma
Interventions: BIOLOGICAL: ACE-041
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of RBT-1 on Reducing the Risk of Post-Operative Complications in Subjects Undergoing Cardiac Surgery
Status: RECRUITING
Conditions: Post-Operative Complications in Cardiac Surgery
Interventions: DRUG: RBT-1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transesophageal Echocardiography to Identify pAtients With Low Risk of Stroke in Atrial Fibrillation - TIARA Pilot Study
Status: COMPLETED
Conditions: Atrial Fibrillation|Stroke
Interventions: PROCEDURE: Transoesophageal echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ozone Therapy in Refractory Ischemic Heart Disease.
Status: TERMINATED
Conditions: Ischemic Heart Disease
Interventions: DRUG: Ozone|DRUG: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b/2, Multicenter, Open-label Study of ACP-196 in Subjects With Recurrent Glioblastoma Multiforme (GBM)
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma Multiforme
Interventions: DRUG: ACP-196
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate Safety, Tolerability, and Pharmacokinetics of MAM01 in African Population
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: MAM01 300 mg SC|DRUG: MAM01 300 mg IM|DRUG: MAM01 600 mg SC|DRUG: MAM01 2000 mg IM|DRUG: MAM01 150 mg SC|DRUG: MAM01 75 mg SC|DRUG: MAM01 225 mg SC|DRUG: MAM01 150 mg IM|DRUG: MAM01 150 mg IV|DRUG: Placebo IV|DRUG: MAM01 150 mg|DRUG: Placebo IM|DRUG: Placebo SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Anti-inflammatory Diet in Autoimmune and Metabolic Diseases
Status: RECRUITING
Conditions: Type1 Diabetes|Obesity
Interventions: DIETARY_SUPPLEMENT: Microbiome-targeted diet|DIETARY_SUPPLEMENT: Usual care diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory, Double-arm, 8-week Study to Explore the Feasibility and Acceptability of Abbreviated Treatment With CT-156 for People With Schizophrenia.
Status: ACTIVE_NOT_RECRUITING
Conditions: Schizophrenia
Interventions: DEVICE: CT-156
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Individualized Dosimetry for Holmium-166-radioembolization in Patients With Unresectable Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma Non-resectable
Interventions: DEVICE: Holmium-166 radioembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SENTI-202: Off-the-shelf Logic Gated CAR NK Cell Therapy in Adults With CD33 and/or FLT3 Blood Cancers Including AML/MDS
Status: RECRUITING
Conditions: AML/MDS|CD33 Expressing Hematological Malignancies|FLT3 Expressing Hematological Malignancies
Interventions: BIOLOGICAL: SENTI-202
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DHEA in Synovial Sarcoma Patients
Status: TERMINATED
Conditions: Synovial Sarcoma|Sarcoma, Synovial
Interventions: DRUG: DHEA|OTHER: FACT-67 validated survey
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Postpartum Nexplanon Placement in Opioid Dependent Women
Status: COMPLETED
Conditions: Opiate Addiction|Pregnancy|Contraceptive Behavior|Sexual Behavior
Interventions: DRUG: Nexplanon (etonogestrel contraceptive implant)|DRUG: Standard postpartum contraceptive care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chemotherapy and Radiotherapy for Osteolymphoma
Status: COMPLETED
Conditions: Osteolymphoma
Interventions: DRUG: Cyclophosphamide, Doxorubicin, Vincristine, Prednisolone.|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment for Individuals Interacting With the Criminal Justice System
Status: NOT_YET_RECRUITING
Conditions: Suicide Risk|Psychiatric Disorders
Interventions: OTHER: Treatment as usual (TAU)|OTHER: Family and Social Justice|OTHER: Family and Social Justice Service and Navigator (FSJS+Navigator) Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Safety and Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of JNJ-54175446 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ 54175446|DRUG: Placebo|OTHER: High fat/high Calorie Breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Weight Reduction in CLBP
Status: RECRUITING
Conditions: Chronic Low-back Pain|Overweight or Obesity
Interventions: BEHAVIORAL: Pain Neuroscience Education|BEHAVIORAL: Cognition-targeted exercise therapy|BEHAVIORAL: Behavioral weight reduction program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep and Emotional Memory in Peripubertal Anxiety
Status: COMPLETED
Conditions: Anxiety
Interventions: BEHAVIORAL: Sleep with Sound Cues|BEHAVIORAL: Sleep with Sham Cues
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: the Pericapsular Nerve Group (PENG) and Suprainguinal Fascia Iliaca Blocks (SIFIB) in Elderly Patients
Status: COMPLETED
Conditions: Collum Femoris Fracture|Pericapsular Nerve Group Block|Suprainguinal Fascia Iliaca Block
Interventions: PROCEDURE: PENG block|PROCEDURE: SIFIB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Vitamin E Ointment on Incisional SSI in Colorectal Surgery
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: DRUG: Vitamin E ointment application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oral Glucocorticoids Effect on Post Endodontic Pain
Status: COMPLETED
Conditions: Pulpitis
Interventions: DRUG: Prednisolone|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Low Dose Prophylactic Naloxone Infusion to Prevent Respiratory Depression With Intrathecal Morphine.
Status: COMPLETED
Conditions: Respiratory Depression
Interventions: DRUG: Naloxone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Coconut Oil Application in Reducing Water Loss From Skin of Premature Babies in First Week of Life (TEWL)
Status: COMPLETED
Conditions: Trans Epidermal Water Loss (TEWL)
Interventions: OTHER: Coconut oil application|OTHER: No oil application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Comparison of AmblyzTM Glasses and Patching for Amblyopia
Status: TERMINATED
Conditions: Amblyopia
Interventions: DEVICE: 4-hour AmblyZ glasses|DEVICE: 12-hour AmblyZ glasses|DEVICE: 2-hour patching|DEVICE: 6-hour patching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Lymphoblastic Lymphoma
Interventions: DRUG: Dexamethasone|DRUG: Vincristine|DRUG: Inotuzumab|DRUG: Blinatumomab|DRUG: Dasatinib|PROCEDURE: IT MHA|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Methotrexate|DRUG: 6-Mercaptopurine|DRUG: Calaspargase|DRUG: Daunorubicin|DRUG: Thioguanine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BL-B01D1 in Patients With Unresectable Locally Advanced or Metastatic Breast Cancer and Other Solid Tumors
Status: RECRUITING
Conditions: Breast Cancer|Solid Tumor
Interventions: DRUG: BL-B01D1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Listening Visits for Emotionally Distressed Mothers of Hospitalized Newborns
Status: COMPLETED
Conditions: Nurse Delivered Counseling|Emotional Distress
Interventions: BEHAVIORAL: RCT Treatment -Listening Visits delivered by NICU nurse in person|BEHAVIORAL: RCT Control Usual mental health care delivered by NICU social workers|BEHAVIORAL: Open trial: Listening Visits delivered by a NICU nurse via zoom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SRS and Nivolumab in Treating Patients With Newly Diagnosed Melanoma Metastases in the Brain or Spine
Status: COMPLETED
Conditions: Metastatic Malignant Neoplasm in the Brain|Metastatic Malignant Neoplasm in the Spine|Stage IV Skin Melanoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab|RADIATION: Stereotactic Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Behavioral Activation for Prolonged Grief
Status: COMPLETED
Conditions: Complicated Grief|Prolonged Grief Disorder|Major Depressive Disorder|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Behavioral Activation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed Disodium and Cisplatin With or Without Cediranib Maleate in Treating Patients With Malignant Pleural Mesothelioma
Status: ACTIVE_NOT_RECRUITING
Conditions: Epithelioid Mesothelioma|Pleural Malignant Mesothelioma|Recurrent Malignant Mesothelioma|Sarcomatoid Mesothelioma
Interventions: DRUG: Cediranib Maleate|DRUG: Cisplatin|OTHER: Laboratory Biomarker Analysis|DRUG: Pemetrexed Disodium|OTHER: Placebo Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trilaciclib in Patients With Early-Stage HR-negative Breast Cancer Receiving Adjuvant Chemotherapy
Status: RECRUITING
Conditions: Breast Neoplasms
Interventions: DRUG: Trilaciclib|DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: Paclitaxel|DRUG: Docetaxel|DRUG: Carboplatin|DRUG: Trastuzumab|DRUG: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hearing Implant Performance in Adults With Low-Frequency Residual Hearing
Status: WITHDRAWN
Conditions: Sensorineural Hearing Loss|Low-Frequency Residual Hearing
Interventions: DEVICE: CI624 Slim 20 Electrode
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Evaluating the Safety, Tolerability, and Pharmacokinetics of Bedaquiline and Delamanid, Alone and in Combination, For Drug-Resistant Pulmonary Tuberculosis
Status: COMPLETED
Conditions: Tuberculosis|HIV Infections
Interventions: DRUG: Bedaquiline|DRUG: Delamanid|DRUG: Dolutegravir|DRUG: Multidrug Background Treatment (MBT) for TB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Biobehavioral Intervention for Young Men With Testicular Cancer
Status: UNKNOWN
Conditions: Testis Cancer
Interventions: BEHAVIORAL: Goal-Focused Emotion Regulation Therapy (GET)|BEHAVIORAL: Individual Supportive Psychotherapy (ISP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: IMPACT OF COMPUTERIZED GLOVE ON FACILITATING HAND FUNCTION RECOVERY AND NEURAL PLASTICITY IN STROKE
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Hand rehabilitation program using the computerized glove|OTHER: Selected hand program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of In-centre Nocturnal Hemodialysis on Ventricular Remodeling and Function in End-stage Renal Disease
Status: COMPLETED
Conditions: End-stage Renal Disease|Left Ventricular Hypertrophy
Interventions: PROCEDURE: Incentre nocturnal hemodialysis|PROCEDURE: Remaining on conventional hemodialysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cadonilimab Plus Nab-Paclitaxel for Recurrent or Metastatic Muscle Invasive Bladder Cancer
Status: RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: Cadonilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SWOG-9321 Melphalan, TBI, and Transplant vs Combo Chemo in Untreated Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: recombinant interferon alfa|DRUG: carmustine|DRUG: cyclophosphamide|DRUG: dexamethasone|DRUG: doxorubicin hydrochloride|DRUG: melphalan|DRUG: prednisone|DRUG: vincristine sulfate|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Posterior-superior Insula Deep Brain Stimulation in Refractory Peripheral Neuropathic Pain Patients
Status: COMPLETED
Conditions: Neuropathic Pain|Neuropathy;Peripheral
Interventions: DEVICE: Deep Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A NIS of Alpelisib in Combination With Fulvestrant in Postmenopausal Women, and Men, With HR+,HER2- , Locally Advanced or Metastatic Breast Cancer With a PIK3CA Mutation, After Disease Progression Following Endocrine Therapy as Monotherapy, in the Real-world Setting
Status: RECRUITING
Conditions: Hormone Receptor Positive HER2 Negative Breast Cancer With a PIK3CA Mutation
Interventions: OTHER: Alpelisib|OTHER: Fulvestrant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preliminary Efficacy and Safety of Ibogaine in the Treatment of Methadone Detoxification
Status: UNKNOWN
Conditions: Drug Dependence|Drug Use Disorders|Opioid Dependence
Interventions: DRUG: Ibogaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurofeedback Training for High Risk Psychosis
Status: COMPLETED
Conditions: Prodromal Schizophrenia
Interventions: BEHAVIORAL: Neurofeedback processing speed training|BEHAVIORAL: Active control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary Stones
Status: RECRUITING
Conditions: Calcium Phosphate Kidney Stones
Interventions: DIETARY_SUPPLEMENT: OHCit- standard dose|DRUG: Potassium Citrate|DRUG: Placebo|DIETARY_SUPPLEMENT: OHCit- low dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I Study of BMS-275183 (Oral Taxane) Given on a Daily Schedule in Combination With Esomeprazole (Nexium) in Patients With Advanced Cancer
Status: TERMINATED
Conditions: Cancer
Interventions: DRUG: Oral Taxane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Placebo/Active Crossover Dose-ranging Study for Safety and Efficacy in Asthma Patients.
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: E004 (epinephrine inhalation aerosol), 90 mcg/actuation|DRUG: E004 Placebo|DRUG: E004 (epinephrine inhalation aerosol), 125 mcg|DRUG: E004 (epinephrine inhalation aerosol), 220 mcg|DRUG: epinephrine inhalation aerosol, CFC propelled|DRUG: E004 (epinephrine inhalation aerosol), 160 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuropathic Pain Assessment Comparing Pregabalin and Paroxetine in Management of MS-induced Neuropathic Pain
Status: COMPLETED
Conditions: Neuropathic Pain|Multiple Sclerosis
Interventions: DRUG: paroxetine|DRUG: pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Combined With Itacitinib (INCB039110) and/or Pembrolizumab Combined With INCB050465 in Advanced Solid Tumors
Status: COMPLETED
Conditions: Colorectal Cancer (CRC)|Endometrial Cancer|Melanoma|Head and Neck Cancer|Lung Cancer|MMR-deficient Tumors|Breast Cancer|Pancreatic Cancer|Renal Cell Carcinoma (RCC)|Solid Tumors|UC (Urothelial Cancer)
Interventions: DRUG: Pembrolizumab|DRUG: itacitinib|DRUG: INCB050465
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of AG-013736 In Patients With Refractory Metastatic Renal Cell Cancer
Status: COMPLETED
Conditions: Kidney Neoplasms|Carcinoma, Renal Cell
Interventions: DRUG: AG-013736 (axitinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use Of Oral Itraconazole In Patients With Locally Limited Basocellular Carcinoma Of Skin.
Status: UNKNOWN
Conditions: Basal Cell Carcinoma|Hedgehog Pathway
Interventions: DRUG: Itraconazole 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tetrandrine in the Treatment of Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tetrandrine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: T-cell Lymphoma|Cutaneous/Peripheral T-Cell Lymphoma|Peripheral T-cell Lymphoma|Peripheral T-Cell Lymphoma, Not Classified|Primary Cutaneous T-cell Lymphoma|Cutaneous T-Cell Lymphoma, Unspecified|Cutaneous T-cell Lymphoma|Follicular T-Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Sézary's Disease|Mycosis Fungoides
Interventions: DRUG: Fenretinide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aripiprazole in the Treatment of Patients With Schizophrenia and Symptoms of Obsessive Compulsive Disorder (OCD)
Status: COMPLETED
Conditions: Schizophrenia OCD|Obsessive Compulsive Disorder
Interventions: DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of XL184 (Cabozantinib) With or Without Erlotinib in Adults With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: XL184|DRUG: erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationship bw Image-deriv Features of Intraoperative ICG Visualiz of NVBs During RARP & Functional Outcome
Status: RECRUITING
Conditions: Prostate Adenocarcinoma
Interventions: DRUG: ICG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Bonding and a Fluoride Varnish for Long-term Dentin Hypersensitivity Treatment.
Status: COMPLETED
Conditions: To Decrease Dentin Hypersensitivity
Interventions: PROCEDURE: Application of varnish fluoride desensitizing agent on buccal surfaces of exposed dentin|PROCEDURE: Application of bonding agent desensitizing agent on buccal surfaces of exposed dentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy in Treating Patients With Resectable Non-Small Cell Lung Cancer That Has Spread to the Pleura
Status: TERMINATED
Conditions: Lung Cancer|Metastatic Cancer
Interventions: DRUG: chemotherapy|DRUG: porfimer sodium|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|PROCEDURE: spectroscopy|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Superior Laryngeal Nerve Block For Awake Endotracheal Intubation Study
Status: TERMINATED
Conditions: Awake Endotracheal Intubation|Difficult Intubation|Airway Anesthesia
Interventions: PROCEDURE: Superior Laryngeal Nerve Block using the Thyrohyoid Membrane as an Anatomic Landmark
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Efficacy and Safety of Lonidamine for the Treatment of Symptomatic Benign Prostatic Hyperplasia
Status: TERMINATED
Conditions: Benign Prostatic Hyperplasia|Enlarged Prostate
Interventions: DRUG: Lonidamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect and Mechanism of Transcutaneous Auricular Vagus Nerve Stimulation on Gait Impairments in PD
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DEVICE: Transcutaneous auricular vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Master Protocol of Novel Combination Therapy for Patients With Relapsed or Refractory Aggressive B-Cell Lymphoma
Status: RECRUITING
Conditions: Lymphoma, B-Cell
Interventions: DRUG: Venetoclax|DRUG: Rituximab Injection|DRUG: Rituximab SC|DRUG: Gemcitabine|DRUG: Dexamethasone|DRUG: Cisplatin|DRUG: Glofitamab|DRUG: Tafasitamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emervel Classic Lidocaine Versus Juvederm® Ultra in Treatment of Moderate to Severe Facial Wrinkles and Folds
Status: COMPLETED
Conditions: Skin Wrinkling
Interventions: DEVICE: Emervel Classic Lidocaine|DEVICE: Juvederm® Ultra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Performance of 3 Sampling Methods for the Detection of SARS-CoV-2 (COVID-19) With Real-time Reverse Transcriptase PCR
Status: TERMINATED
Conditions: Covid-19|SARS-CoV-2|Diagnosis|Polymerase Chain Reaction
Interventions: OTHER: samling of oropharynx and nasopharynx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of an Online Psychoeducation Program for Improving Coping in People With a High Level of Dissociative Symptoms: A Pilot Randomized Waitlist-controlled Trial
Status: COMPLETED
Conditions: Dissociation
Interventions: BEHAVIORAL: Online psychoeducational program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Avelumab or Hydroxychloroquine With or Without Palbociclib to Eliminate Dormant Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: HCQ|DRUG: Avelumab|DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effect of Nasal Spray in the Prevention of RTI in Children With Pre-school Wheezing
Status: RECRUITING
Conditions: Wheezing|Recurrent Respiratory Tract Infections
Interventions: DEVICE: Resveratrol + CMG|DEVICE: Isotonic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Tailored H. Pylori Eradication Based on Clarithromycin Resistance
Status: COMPLETED
Conditions: Helicobacter Pylori Infection|Antibiotic Resistant Strain
Interventions: DRUG: proton pump inhibitor, amoxicillin, clarithromycin|DRUG: proton pump inhibitor, amoxicillin, metronidazole
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Regional Blocks of Gynecological Surgeries
Status: COMPLETED
Conditions: Gynecologic Disease Requiring Vaginal Operation Under Neuraxial Anesthesia
Interventions: PROCEDURE: Standard Lumbar Epidural Technique|PROCEDURE: 25G Dural Puncture Epidural Technique|PROCEDURE: 27G Dural Puncture Epidural Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sciatic Nerve Blocks With or Without Femoral Block Versus Spinal Anaesthesia in Patients Undergoing Diabetic Foot Surgery
Status: COMPLETED
Conditions: Diabetic Foot
Interventions: PROCEDURE: Sciatic with or without femoral block|PROCEDURE: Spinal anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Epidural Magnesium Sulfate for Post-thoracotomy Pain Control
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: magnesium sulfate|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Use of Image-Based Computer Gradings in the Analysis of Acne, Rosacea, Melasma, and Seborrheic Dermatitis
Status: RECRUITING
Conditions: Acne|Melasma|Rosacea|Seborrheic Dermatitis
Interventions: OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Combination of ATRA and High-dose Dexamethasone as First-line Treatment in Adult Immune Thrombocytopenia
Status: COMPLETED
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Dexamethasone|DRUG: ATRA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduction Of Cycles of neOadjuvant Chemotherapy for Advanced Epithelial Ovarian, Fallopian and Primary Peritoneal Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer Stage IIIC|Ovarian Cancer Stage IV|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: DRUG: Two cycles of neoadjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Volume-Controlled Ventilation and Pressure-Controlled Ventilation Volume Guaranteed in Obese Patients in Laparoscopic-Assisted Surgery
Status: RECRUITING
Conditions: Volume-Controlled Ventilation|Pressure-Controlled Ventilation Volume Guaranteed|Obese|Laparoscopy
Interventions: OTHER: Pressure controlled ventilation-volume guaranteed|OTHER: Volume controlled ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Smoke-Free Home Intervention in Tribal Communities
Status: NOT_YET_RECRUITING
Conditions: Tobacco-Related Carcinoma
Interventions: OTHER: Best Practice|BEHAVIORAL: Smoking Cessation Intervention|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Intranasal Midazolam Versus Ketamine Midazolam Combination as a Premedication on the Occurrence of Postoperative Respiratory Adverse Events
Status: RECRUITING
Conditions: Tonsillectomy|Adenoidectomy|Drug-Related Side Effects and Adverse Reaction
Interventions: DRUG: The midazolam group|DRUG: The midazolam ketamine group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Two Positions for Free Floating Tracheal Intubation in Weightlessness
Status: COMPLETED
Conditions: Intubation; Difficult or Failed|Intubation Complication
Interventions: DEVICE: Videolaryngoscopy / Direct Laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ADALISKIAS: Adalimumab for Acute Disc Prolapse
Status: UNKNOWN
Conditions: Disc Prolapse|Pain
Interventions: BIOLOGICAL: Adalimumab injections for acute disc prolapse patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ProAgio in Previously Treated Advanced Pancreatic Cancer and Other Solid Tumor Malignancies
Status: RECRUITING
Conditions: Advanced Pancreatic Cancer|Solid Tumor Malignancies
Interventions: DRUG: ProAgio Dose Levels (DL) 1,2,3|DRUG: ProAgio Dose Levels (DL) 4,5,6|DRUG: ProAgio Dose Levels 4a,5a,6a
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Easy-to-Read Informed Consent (ETRIC) for Hematopoietic Cell Transplantation Clinical Trials (BMT CTN 1205)
Status: COMPLETED
Conditions: Improve the Informed Consent Process
Interventions: OTHER: Consent Form Specific Format 1|OTHER: Consent Form Specific Format 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Evaluate Efficacy and Safety of Mepolizumab for Frequently Exacerbating Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Mepolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Efficacy of Immunomodulators in RA Patients
Status: RECRUITING
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Iguratimod|DRUG: Methotrexate|DRUG: Adalimumab Injection|DRUG: Leflunomide|DRUG: Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of CFS and Fibromyalgia With HRG 80 Red Ginseng
Status: UNKNOWN
Conditions: Fibromyalgia|CFS
Interventions: DIETARY_SUPPLEMENT: HRG 80 Red Ginseng
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Role of Treatment With Vitamin E on Asthmatic Responses in Allergic Asthmatics
Status: COMPLETED
Conditions: Allergic Asthma
Interventions: DRUG: Natural source d-α-tocopheryl acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Protein Concentration on Human Embryo Development
Status: COMPLETED
Conditions: Human Embryo Culture
Interventions: OTHER: Effect of Protein on Blastocyst Development
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER