pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effectiveness of the WHO Caregivers Skills Training Program
Status: UNKNOWN
Conditions: Autism Spectrum Disorder|Development Delay|Developmental Disorder|Language Delay|Behavioral Problem|Emotional Problem|Maternal Distress
Interventions: BEHAVIORAL: WHO Caregiver skills training (CST) program|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of DAPD Alone Versus DAPD Plus MMF for Treatment of HIV Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Mycophenolate mofetil|DRUG: Amdoxovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Placental Transfusion in Term Infants: A Pilot Study
Status: COMPLETED
Conditions: Anemia
Interventions: PROCEDURE: cord clamping at 2 minutes|PROCEDURE: cord clamping at 5 minutes|PROCEDURE: cord milking
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Efficacy and Safety of Vibegron (MK-4618) in Participants With Overactive Bladder (OAB) (MK-4618-008)
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: Vibegron|DRUG: Tolterodine ER|DRUG: Placebo matching vibegron|DRUG: Placebo matching tolterodine ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Purslane in Treatment of Oral Lichen Planus
Status: COMPLETED
Conditions: Lichen Planus, Oral
Interventions: DRUG: Purslane 235mg/day in one dosage|DRUG: Placebo : one dosage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Immunotherapy in Locally Advanced Colon Cancers
Status: NOT_YET_RECRUITING
Conditions: Colon Cancer|Immunotherapy
Interventions: DRUG: Terelizumab|DRUG: CapeOx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Stage D0 Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: BCG vaccine|BIOLOGICAL: prostate cancer vaccine ONY-P1|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SGLT2 Inhibitor TrEatment iN Patients Awaiting cOronary arTery bYpass Surgery to Reduce Post-opErative AF
Status: RECRUITING
Conditions: Chronic Coronary Syndrome|Atrial Fibrillation
Interventions: DRUG: Dapagliflozin 10mg Tab|DRUG: Placebo Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Real-time Navigation for Laparoscope Liver Resections Using Fusion 3D Imaging and Indocyanine Green Fluorescence Imaging
Status: UNKNOWN
Conditions: Liver Resection
Interventions: DEVICE: Laparoscopic surgical navigation system|DRUG: Indocyanine Green
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Safety Extension Study of 2.5, 5 and 10 mg of Vortioxetine (Lu AA21004) in Long-term Treatment of Major Depressive Disorder in Adults
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Vortioxetine (Lu AA21004)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy, Surgery, and Radiation Therapy in Treating Children With Advanced Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: BIOLOGICAL: filgrastim|DRUG: doxorubicin hydrochloride|DRUG: ifosfamide|DRUG: mesna|DRUG: vincristine sulfate|PROCEDURE: conventional surgery|RADIATION: brachytherapy|RADIATION: low-LET cobalt-60 gamma ray therapy|RADIATION: low-LET electron therapy|RADIATION: low-LET photon therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Combination Therapy With INCMGA00012 (Anti-PD-1), INCAGN02385 (Anti-LAG-3), and INCAGN02390 (Anti-TIM-3) in Participants With Select Advanced Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: DRUG: INCAGN02385|DRUG: INCAGN02390|DRUG: INCMGA00012.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthy Lifestyles After Cancer for Adolescents and Young Adults: A Program to Reduce Cardiovascular Risk Factors
Status: RECRUITING
Conditions: Cancer|Cardiovascular Diseases|Weight Management|Pain|Fatigue|Distress, Emotional|Physical Inactivity
Interventions: BEHAVIORAL: HEALTHY AYA|OTHER: Education Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Extension Study of APD334-003 in Patients With Moderately to Severely Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Etrasimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Stool DNA Test for Detection of Advanced Colorectal Neoplasia in Asymptomatic Chinese Community Population
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Neoplasm|Advanced Adenoma|Adenoma|Serrated Lesion
Interventions: DIAGNOSTIC_TEST: Stool-based SDC2 DNA methylation test|DIAGNOSTIC_TEST: quantitative Fecal immunochemical test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Neoadjuvant Nivolumab + Palbociclib + Anastrozole in Post-Menopausal Women and Men With Primary Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Cancer
Interventions: BIOLOGICAL: Nivolumab|DRUG: Anastrozole|DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterizing Sleep Among Long-term Survivors of Childhood Cancer
Status: RECRUITING
Conditions: ALL, Adult|CNS Tumor|Solid Tumor
Interventions: OTHER: Neurocognitive (Thinking) Testing|DIAGNOSTIC_TEST: CNS Vital Signs (Thinking) Testing|OTHER: Health Questionnaires, Sleep Surveys & Sleep Diary|DIAGNOSTIC_TEST: Echocardiography/EKG|DIAGNOSTIC_TEST: Pulmonary Function|DEVICE: Remote Polysomnography|DIAGNOSTIC_TEST: Physical Function
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Samples on Acne Treatment With Epiduo® Gel
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Adapalene + benzoyl peroxide samples|DRUG: Adapalene + benzoyl peroxide from standard tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Proof-of-Concept Study of AC-201 to Prevent Gout Flares
Status: COMPLETED
Conditions: Gout Flares
Interventions: DRUG: Placebo|DRUG: AC-201|DRUG: Febuxostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Fosfomycin Plus Imipenem for Treatment of Infective Endocarditis
Status: COMPLETED
Conditions: Infective Endocarditis
Interventions: DRUG: Fosfomycin and imipenem|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myoslow Lens Study to Control Myopia in Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Myopia
Interventions: DEVICE: Myoslow|DEVICE: Single Vision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Time to Symptom Relief and Elimination of Infecting Bacteria in Treating Sinusitis With Avelox
Status: COMPLETED
Conditions: Maxillary Sinusitis
Interventions: DRUG: Avelox (Moxifloxacin, BAY12-8039)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Music Intervention on Pain Control In First Trimester Surgical Abortion Under Local Anesthesia
Status: COMPLETED
Conditions: First Trimester Abortion|Surgical Abortion|Music Intervention|Local Anesthesia|Pain
Interventions: BEHAVIORAL: Music intervention group|BEHAVIORAL: Controlled group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Trial of High Dose Oral Vitamin D3 With Calcium in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of The Effect Of CP-751,871 In Combination With Gemcitabine And Cisplatin In Patients With Advanced Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: CP-751,871|DRUG: Cisplatin|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research for Specific Proteins of Interest for the Serological Diagnosis of Bird Fancier's Lung
Status: COMPLETED
Conditions: Avian Hypersensitivity Pneumonitis
Interventions: OTHER: additional blood sample|OTHER: respiratory functional exploration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison Study for Bile Reflux and Gastric Stasis in Patients After Distal Gastrectomy
Status: WITHDRAWN
Conditions: Stomach Cancer|Gastrectomy
Interventions: PROCEDURE: Billroth-II (B-II)|PROCEDURE: Roux en Y gastrojejunostomy (RY-GJ)|PROCEDURE: uncut Roux en Y gastrojejunostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addressing Health Disparities in Normal Pressure Hydrocephalus (NPH) in Maryland
Status: NOT_YET_RECRUITING
Conditions: Normal Pressure Hydrocephalus|Hakim Syndrome
Interventions: OTHER: patients will receive NPH education|OTHER: primary care physicians (PCPs) will receive professional NPH education|OTHER: A community health worker will assist PCP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Proton Radiation to the Brain and Spinal Cord for Patients With Leptomeningeal Metastases
Status: COMPLETED
Conditions: Leptomeningeal Metastases
Interventions: RADIATION: Proton craniospinal irradiation (CSI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Best Treatment for Women With Both (Polycystic Ovary Syndrome) PCOS and Subclinical Hypothyroidism
Status: RECRUITING
Conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries|Subclinical Hypothyroidism|Female Infertility
Interventions: DRUG: Letrozole 2.5mg|DRUG: Levothyroxine 25 Mcg (0.025 Mg) Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Talimogene Laherparepvec Compared to Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) in Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: Talimogene laherparepvec|BIOLOGICAL: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Viberect Penile Vibratory Stimulation to Enhance Recovery of Erectile Function and Urinary Continence Post-Prostatectomy
Status: WITHDRAWN
Conditions: Erectile Dysfunction Following Radical Prostatectomy|Urinary Incontinence of Non-organic Origin
Interventions: DEVICE: Viberect device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sulfonylurea Add-on Study in Patients With Type 2 Diabetes Mellitus (0431-035)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Comparator: Sitagliptin|DRUG: Comparator: Placebo|DRUG: Comparator: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Hypertrophic Scars or Keloids
Status: UNKNOWN
Conditions: Hypertrophic Scars
Interventions: OTHER: silicone gel|OTHER: silicone sheet|OTHER: paper tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate a Single Intravenous Dose of Motavizumab for the Treatment of Children Hospitalized With Respiratory Syncytial Virus (RSV) Illness
Status: COMPLETED
Conditions: RSV Illness in ≤12 Months of Participants
Interventions: BIOLOGICAL: Motavizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Vitamin D in Innate Immunity to Tuberculosis
Status: COMPLETED
Conditions: Vitamin D Deficiency|Tuberculosis
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: CRACK-TARGET 1: ÉTUDE DESCRIPTIVE DE LA SENSIBILISATION COMPORTEMENTALE OBSERVÉE et ATTENTES
Status: NOT_YET_RECRUITING
Conditions: Cocaine Use Disorder
Interventions: BEHAVIORAL: Observation of behavior and search of biomarkers with 3 blood tests.3 weeks wearing an actimeter|BIOLOGICAL: 3 blood tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess the Absorption, Metabolism and Excretion of 14C-JNJ-63623872 After a Single Dose in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-63623872
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Leucovorin Pharmacokinetic Study in Patients Receiving High Dose Methotrexate With or Without Voraxaze
Status: COMPLETED
Conditions: Osteosarcoma|Leukemia|Lymphoma
Interventions: DRUG: glucarpidase, high-dose methotrexate, leucovorin|DRUG: high-dose methotrexate, leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Montelukast in Mild-moderate Respiratory Symptoms in Patients With Long-COVID-19:
Status: TERMINATED
Conditions: Covid19|SARS (Disease)
Interventions: DRUG: Montelukast|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Community Ambulation After Hip Fracture
Status: COMPLETED
Conditions: Hip Fracture
Interventions: DIETARY_SUPPLEMENT: Nutrition|BEHAVIORAL: PUSH|BEHAVIORAL: PULSE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioavailability Study of Doxycycline Monohydrate Capsules and Monodox Under Fasting and Fed Conditions
Status: COMPLETED
Conditions: To Determine Bioequivalence Under Fed Conditions
Interventions: DRUG: Doxycycline monohydrate|DRUG: Monodox|DRUG: Doxycycline Monohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Carbon Dioxide Surgical Field Flooding and Aortic No-touch Off-pump Coronary Artery Bypass Grafting to Reduce Neurological Injuries After Surgical Coronary Revascularization (CANON): a Randomised, Controlled, Investigator and Patient Blinded Single Center Superiority Trial With Three Parallel Arms.
Status: COMPLETED
Conditions: Neurological Injury|Stroke|Postoperative Cognitive Dysfunction|Postoperative Delirium|Coronary Artery Disease|Coronary Artery Bypass Surgery|Off-Pump Coronary Artery Bypass
Interventions: PROCEDURE: aortic no-touch OPCABG|PROCEDURE: OPCABG with partial clamp applying carbon dioxide|PROCEDURE: OPCABG with partial clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cinacalcet to Treat Familial Primary Hyperparathyroidism
Status: COMPLETED
Conditions: Hypercalcemia|Familial Primary Hyperparathyroidism
Interventions: PROCEDURE: Parathyroid hormone testing|PROCEDURE: Serum calcium testing
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Trial Of AG-013736, Cisplatin, And Gemcitabine For Patients With Squamous Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung (NSCLC)
Interventions: DRUG: AG-013736|DRUG: gemcitabine|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasal Potential Studies Utilizing Cystic Fibrosis Transmembrane Regulator (CFTR) Modulators
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: OTHER: quercetin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Glenosphere Size on Range of Motion in Female Patients Undergoing Reverse Shoulder Arthroplasty
Status: UNKNOWN
Conditions: Rotator Cuff Tear Arthropathy|Massive Irreparable Rotator Cuff Tear
Interventions: DEVICE: Glenosphere size for Reverse Shoulder Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of RAG-01 in Patients With Non-muscle-invasive Bladder Cancer (NMIBC) Who Have Failed Bacillus Calmette Guérin (BCG) Therapy
Status: RECRUITING
Conditions: Non-Muscle-Invasive Bladder Cancer (NMIBC)
Interventions: DRUG: RAG-01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Colorectal Benefits of Pulses Supplementation
Status: RECRUITING
Conditions: Colorectal Polyp|Obesity
Interventions: DIETARY_SUPPLEMENT: Dry beans|DIETARY_SUPPLEMENT: Usual diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Ridaforolimus on the Pharmacokinetics of Midazolam (Study MK-8669-044)
Status: COMPLETED
Conditions: Relapsed or Refractory Advanced Cancer
Interventions: DRUG: Midazolam|DRUG: Ridaforolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of MF4637 for Correcting the Omega-3 Nutritional Deficiency in NAFLD Patients
Status: COMPLETED
Conditions: Non Alcoholic Fatty Liver
Interventions: DIETARY_SUPPLEMENT: Omega-3|DIETARY_SUPPLEMENT: Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Protamine Dose Reduction on Platelet Aggregation After Extracorporeal Circulation for Minimally Invasive Aortic Valve Replacement Surgery
Status: NOT_YET_RECRUITING
Conditions: Protamine Dose|Protamine Adverse Reaction
Interventions: DRUG: Low dose protamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Study Comparing the Clinical Evlauation Methods ( C) and / or Ultrasound Method ( B or D) in Rheumatoid Arthritis to Adapt Treatment
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DEVICE: Xrays|DEVICE: Ultrasound (B mode )|DEVICE: Ultrasound (D mode)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Adoptive Therapy Using Antigen-Specific CD4 T-Cells
Status: WITHDRAWN
Conditions: Melanoma|Sarcoma
Interventions: DRUG: Ipilimumab|DRUG: Cyclophosphamide|BIOLOGICAL: CD4+ T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Assessment of the PDA-FIT System in Type 1 Diabetic Patients
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: placebo|DEVICE: VISITS + PDA-FIT system|DEVICE: PDA-FIT System + telephone follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Accelerating Implementation of Mindful Mood Balance for Moms
Status: COMPLETED
Conditions: Perinatal Depression
Interventions: BEHAVIORAL: MMBFM program with clinician coach support|BEHAVIORAL: MMBFM program with peer coach support|BEHAVIORAL: Patient facing strategy intervention arm|BEHAVIORAL: Patient facing plus clinic facing strategy intervention arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Patients With Breast Cancer Using DCE-MRI, MRS, and Proteomics
Status: COMPLETED
Conditions: Breast Cancer
Interventions: GENETIC: proteomic profiling|PROCEDURE: lumpectomy or mastectomy|PROCEDURE: dynamic contrast-enhanced magnetic resonance imaging|PROCEDURE: histopathologic examination|PROCEDURE: magnetic resonance spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy Study of Iontophoresis and Dexamethasone Phosphate to Treat Dry Eye
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DRUG: EGP-437 with EyeGate® II System|DRUG: Sodium citrate buffer solution with EyeGate® II System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Fermented Maillard Reacted Whey Protein on Immune Function
Status: COMPLETED
Conditions: Immune Deficiency
Interventions: DIETARY_SUPPLEMENT: Fermented Maillard reacted whey protein (F-MRP)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Renal Denervation by MDT-2211 System in Patients With Uncontrolled Hypertension
Status: COMPLETED
Conditions: Uncontrolled Hypertension
Interventions: DEVICE: MDT-2211 Renal Denervation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgetic and Anxiolytic Effect of Preoperative Pregabalin
Status: COMPLETED
Conditions: Intervertebral Disk Displacement|Disk Prolapse
Interventions: DRUG: pregabalin|DRUG: Placebo|DRUG: morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving the Experience of Exercise Among Individuals With Internalized Weight Bias Using Acceptance-based Strategies
Status: UNKNOWN
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Acceptance and Commitment|BEHAVIORAL: Multi-Health Behavior
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Awakening and Impact on Cognitive Function After Administration of Sugammadex in Robotic Radical Cystectomy
Status: COMPLETED
Conditions: Anesthesiology Management
Interventions: DRUG: sugammadex|DRUG: Neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Trial of Amrubicin and Carboplatin With Pegfilgrastim in Patients With Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Extensive-Stage Small Cell Lung Cancer
Interventions: DRUG: Amrubicin|DRUG: Carboplatin|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of AMD070 When Administered Alone or Boosted With Low-Dose Ritonavir in HIV Uninfected Men
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Ritonavir|DRUG: AMD070
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Sample Collection to Evaluate Biomarkers in Subjects With Untreated Solid Tumors
Status: COMPLETED
Conditions: Breast Cancer|Lung Cancer|Colorectal Cancer|Prostate Cancer|Bladder Cancer|Uterine Cancer|Kidney Cancer|Renal Pelvis Cancer|Pancreatic Cancer|Liver Cancer|Stomach Cancer|Ovarian Cancer|Esophageal Cancer
Interventions: OTHER: Blood Sample Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Verticality Perception - Multisensory Contribution
Status: COMPLETED
Conditions: Verticality Perception in Healthy Human Subjects|Individual Contribution of Different Sensory Systems
Interventions: OTHER: Vestibular stimulation by use of the turntable (static roll-tilt while the head is roll-tilted relative to the trunk)|OTHER: 3D-video-head impulse testing|OTHER: Vestibular-evoked myogenic potentials (VEMPs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioavailability of Clormadinone/Ethinyl Estradiol Tablets 2 mg/0.02 mg With Regards to Reference Product
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Clormadinone 2 mg and Ethinyl estradiol 0.02 mg Test Product Coated Tablets|DRUG: Clormadinone 2 mg and Ethinyl estradiol 0.02 mg Reference Product Coated Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diamine Silver Fluoride and Potassium Iodide
Status: COMPLETED
Conditions: Dentine Caries
Interventions: OTHER: Silver Diamine fluoride|OTHER: Potassium iodide|OTHER: Chlorhexidine|OTHER: Silver diamine fluoride and potassium iodide|OTHER: Physiological saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Total Cardiovascular Risk in an Urban Community
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Coronary Disease|Diabetes Mellitus|Atherosclerosis|Cerebral Arteriosclerosis|Hypertension
Interventions: BEHAVIORAL: Lifestyle Changes|DRUG: Antiplatelet Agents|DRUG: Beta Blocker|DRUG: ACE Inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transcutaneous Vagal Nerve Stimulation in Veterans With Posttraumatic Stress Disorder
Status: RECRUITING
Conditions: Stress Disorders, Post-Traumatic
Interventions: DEVICE: tcVNS|DEVICE: sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tunnel Technique With Emdogain® in Addition to Connective Tissue Graft Compared With Connective Tissue Graft Alone for the Treatment of Gingival Recessions: a Randomized Clinical Trial.
Status: UNKNOWN
Conditions: Gingival Recession
Interventions: DEVICE: The tunnel technique for root coverage with Emdogain|DEVICE: The tunnel technique for root coverage without Emdogain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intramuscular Versus Intravenous Prophylactic Oxytocin for Hemorrhage After Vaginal Delivery
Status: UNKNOWN
Conditions: Postpartum Hemorrhage
Interventions: DRUG: intarvenous and intramusculer 10 IU oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Transplantation of Bone Marrow Mononuclear Cell (BM-MNC) With and Without Granulocyte-Colony Stimulation Factor (G-CSF) for Treatment of Chronic Lower Limb Ischemic Patients
Status: COMPLETED
Conditions: Peripheral Vascular Diseases|Ischemia
Interventions: BIOLOGICAL: BM-MNC injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BCAA Supplementation for Concussion
Status: COMPLETED
Conditions: Brain Concussion
Interventions: DRUG: Branched Chain Amino Acids|DRUG: Placebo solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized-Controlled Lifestyle Intervention to Increase Physical Activity Levels in Adolescents
Status: COMPLETED
Conditions: Life Style, Healthy|Life Style
Interventions: BEHAVIORAL: Promotion of physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Spanish Randomized Clinical Trial to Compare Levosimendan Versus Placebo in Postoperative Cardiac Surgery (SPARTANS)
Status: UNKNOWN
Conditions: Cardiac Output, Low
Interventions: DRUG: Levosimendan|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BiLAteral Hypoglossal Nerve Stimulation for Treatment of Obstructive Sleep Apnoea (BLAST OSA)
Status: COMPLETED
Conditions: Obstructive Sleep Apnea of Adult
Interventions: DEVICE: Genio(TM) bilateral hypoglossal nerve stimulation system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Ability of and Safety of GSK2110183 in Treating Langerhans Cell Histiocytosis
Status: COMPLETED
Conditions: Langerhans Cell Histiocytosis
Interventions: DRUG: GSK2110183
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assess the Effect of Cangrelor at the Therapeutic Dose and a Supratherapeutic Dose Level on the QT/QTc Interval in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: cangrelor|DRUG: cangrelor|DRUG: cangrelor|DRUG: moxifloxacin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Multicenter Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel When Used to Treat Actinic Keratoses (AKs) on the Non Head Locations
Status: COMPLETED
Conditions: Actinic Keratoses
Interventions: DRUG: PEP005 (ingenol mebutate) Gel|DRUG: Vehicle gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Irrigants on Outcome of Non Surgical Endodontic Retreatment
Status: COMPLETED
Conditions: Root Canal Infection
Interventions: PROCEDURE: sodium hypochlorite|PROCEDURE: chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study to Evaluate Safety and Efficacy of RM-131 Administered to Patients With Chronic Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: RM-131|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Ability of a Supplement to Increase Good Bacteria in the Human Intestine and Blood Sugar Levels
Status: COMPLETED
Conditions: Pre-diabetic
Interventions: DIETARY_SUPPLEMENT: Sugar Pill|DIETARY_SUPPLEMENT: XOS 2.8
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Biological Anchorage With Selective Micro-osteoperforations (MOPs) in Canine Distalization
Status: TERMINATED
Conditions: Teeth Mesial Drift|Bone Injury|Orthodontic Pathological Resorption of External Root
Interventions: PROCEDURE: micro-osteoperforations (MOPs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Brain Training Games on Cognitive Function and Quality of Life in MCI
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: OTHER: Brain training game Lumosity|OTHER: Simulation game simcity buildit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Sleeve Gastroplasty Versus GLP-1 Analogue for Class 1 and 2 Obesity Study
Status: NOT_YET_RECRUITING
Conditions: Obesity
Interventions: PROCEDURE: Endoscopic sleeve gastroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Eyelid Margin Debridement on Contact Lens Discomfort
Status: COMPLETED
Conditions: Contact Lens Discomfort
Interventions: DEVICE: BlephEx|OTHER: Lid Hygenix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MOIST Study: Multi-Organ Imaging With Serial Testing in COVID-19 Infected Patients
Status: COMPLETED
Conditions: Covid19|Coronavirus Infection|SARS-CoV Infection
Interventions: DIAGNOSTIC_TEST: MRI (heart, brain, lungs, liver)|DIAGNOSTIC_TEST: Bloodwork|OTHER: Cognitive testing|OTHER: Olfaction testing|DIAGNOSTIC_TEST: Spirometry|OTHER: Walk Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of a Low Sodium-High Potassium Salt on Blood Pressure in Vietnamese Adults
Status: COMPLETED
Conditions: Hypertension
Interventions: OTHER: Low-sodium, high-potassium salt|OTHER: Regular salt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacological and Behavioral Treatment After Bariatric Surgery: Medication Change for Non-Responders (Stage 2b)
Status: ENROLLING_BY_INVITATION
Conditions: Loss-of-control Eating|Obesity/Overweight
Interventions: DRUG: Lisdexamfetamine Dimesylate (Medication)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Double-Blind Clinical Trial of Rebamipide vs Esomeprazole in the Treatment of NSAID-induced Gastropathy
Status: COMPLETED
Conditions: NSAID Induced Gastropathy
Interventions: DRUG: Rebamipide and Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective, Multicenter, Case-Control Analysis of the VersaTie Posterior Fixation System to Prevent Proximal Junctional Failure in Long Posterior Spinal Fusion Constructs for Adult Patients
Status: RECRUITING
Conditions: Adult Spinal Deformity|Scoliosis|Kyphosis
Interventions: PROCEDURE: Index or revision spine surgery for complex adult spinal deformity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Deep Brain Stimulation Recovery in Treatment-Resistant Schizophrenia
Status: UNKNOWN
Conditions: Treatment-resistant Schizophrenia|Deep Brain Stimulation
Interventions: DEVICE: On-Stimulation|DEVICE: Off-Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Two Dosage Forms of LY2886721 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: LY2886721 in a Capsule|DRUG: LY2886721 in an orally disintegrating tablet (ODT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anesthetic and Perioperative Risk Assessment Before Programmed Surgery: Anesthetic Teleconsultation Versus Face-to-face Anesthesia Consultation.
Status: UNKNOWN
Conditions: Telemedicine|Anesthesia|Consultation, Remote
Interventions: OTHER: Face-to-face anesthesia consultation|OTHER: Remote anesthesia consultation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I/II Carfilzomib Plus Lenalidomide and Rituximab in the Treatment of Relapsed/Refractory Mantle Cell Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: DRUG: Carfilzomib|DRUG: Lenalidomide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of High- and Low-sodium Intake on the Pharmacokinetics and Pharmacodynamic Effects of Fimasartan
Status: COMPLETED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: High-sodium diet|DIETARY_SUPPLEMENT: low-sodium diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Versus Silver Diamine Fluoride in Hall Technique in Primary Teeth
Status: COMPLETED
Conditions: Carious Teeth
Interventions: DRUG: SDF with stainless steel crown|DEVICE: Diode laser application with stainless steel crown|OTHER: stainless steel crown only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Talactoferrin in Previously Treated Patients With Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Talactoferrin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ejaculatory Sparing vs. Non-ejaculatory Sparing GreenLight Laser Photoselective Vaporization of the Prostate
Status: UNKNOWN
Conditions: Prostatic Hyperplasia
Interventions: PROCEDURE: Non-ejaculatory sparring PVP|PROCEDURE: Ejaculatory sparring PVP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Tixagevimab/Cilgavimab and Regdanvimab Efficacy for Treatment of COVID-19
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronavirus Infections
Interventions: DRUG: tixagevimab/cilgavimab 150+150 mg|DRUG: tixagevimab/cilgavimab 300+300 mg|DRUG: regdanvimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy and Safety of TJO-087 in Moderate to Severe Dry Eye Disease Patients
Status: UNKNOWN
Conditions: Dry Eye Syndrome
Interventions: DRUG: TJO-087|DRUG: Cyclosporine ophthalmic solution 0.05%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Acular LS Versus Nevanac for Pain Control in Eyes Undergoing PRK
Status: COMPLETED
Conditions: Myopia|Hyperopia
Interventions: DRUG: ketorolac (Acular LS)|DRUG: Nepafenac (Nevanac)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Attenuation of Cardiac Effects of Arteriovenous Fistula Creation With Losartan
Status: COMPLETED
Conditions: Renal Failure|Left Ventricular Hypertrophy
Interventions: DRUG: losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of Tattoo Removal Using a Novel Dual-Wavelength, Dual-Pulse Duration Laser
Status: WITHDRAWN
Conditions: Laser Tattoo Removal
Interventions: DEVICE: 532-nm KTP/1064-nm Nd:YAG Dual-Pulse Duration Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EEG Profiles During General Anesthesia : a Comparative Study Between Sevoflurane and Propofol
Status: COMPLETED
Conditions: Anesthesia
Interventions: DEVICE: EEG monitoring|DEVICE: Target Controlled Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Registry - Use of a High Intensity Focused Ultrasound (HIFU) in Patients With Non-malignant Thyroid Nodules.
Status: COMPLETED
Conditions: Non-malignant Thyroid Nodule
Interventions: DEVICE: HIFU treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of TNX-102 SL in Subjects With Military-Related PTSD and Related Conditions
Status: COMPLETED
Conditions: PTSD
Interventions: DRUG: TNX-102 SL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic and Chronobiological Changes in Vestibular Rehabilitation
Status: COMPLETED
Conditions: Vestibular Disorder|Metabolic Disease|Sleep Disorder
Interventions: PROCEDURE: Vestibular Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 3-year Follow-up of Clinical Outcome After Antipsychotic Treatment Discontinuation in Psychosis Individuals
Status: COMPLETED
Conditions: Schizophrenia|Schizophrenia Relapse|Schizophrenia Spectrum and Other Psychotic Disorders
Interventions: OTHER: Antipsychotic treatment discontinuation|OTHER: Maintenance antipsychotic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptive Pet Study
Status: COMPLETED
Conditions: Head and Neck Cancers|Lung and Esophagus Cancers|Anal, Cervix, Vulvar, Vaginal, and Endometrium Cancers
Interventions: OTHER: PET-CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Spinal Cord Stimulation for the Treatment of Motor and Nonmotor Symptoms of Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson's Disease
Interventions: PROCEDURE: Implantable spinal cord stimulation|PROCEDURE: Implantable spinal cord stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Analysis of the Response of Human Tumor Microvascular Endothelium to Ionizing Radiation
Status: COMPLETED
Conditions: Ovarian Neoplasms|Colorectal Neoplasms|Melanoma|Small Cell Lung Cancer|Liposarcoma
Interventions: RADIATION: Ionizing radiation (IR) therapy|RADIATION: Ionizing radiation (IR)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: International Multicenter Comparative Randomized Placebo-controlled Clinical Study of Efficacy and Safety of BCD-085 in Patients With Ankylosing Spondylitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Ankylosing Spondylitis
Interventions: DRUG: BCD-085|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin Treatment in Craniofacial, Inguinal, Palmar, Plantar and Truncal Hyperhidrosis
Status: UNKNOWN
Conditions: Hyperhidrosis
Interventions: DRUG: Botox (onabotulinumtoxinA)|DRUG: NeuroBloc/Myobloc (rimabotulinumtoxinB)|DRUG: NaCl (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multidiscipline Care for Acute Kidney Disease (AKD)
Status: RECRUITING
Conditions: Acute Kidney Injury
Interventions: DRUG: never received RAAS blockers or received RAAS blockers before AKI.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Prevention Messages for EGMs: Effects on Behaviours and Cognitions
Status: RECRUITING
Conditions: Gambling
Interventions: BEHAVIORAL: Prevention pop-up messages|BEHAVIORAL: Mandatory time limit|BEHAVIORAL: Responsible gambling information|DEVICE: Electronic gambling machine (model IGT GL20)|DEVICE: Square terminal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION