pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Phase III Trial of With Marizomib in Patients With Newly Diagnosed Glioblastoma
Status: COMPLETED
Conditions: Newly Diagnosed Glioblastoma
Interventions: DRUG: Marizomib|DRUG: Temozolomide|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Incidence of Hypoglycemia in Insulin Glargine-Treated Subjects With Diabetes Mellitus Upon Switching Between Bedtime and Morning Dosing
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: INSULIN GLARGINE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nonintubated Versus Intubated Anesthesia in Video-assisted Thoracic Surgery
Status: SUSPENDED
Conditions: Intubation
Interventions: OTHER: Laryngeal mask|OTHER: double lumen tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: WASH Benefits Bangladesh
Status: UNKNOWN
Conditions: Malnutrition|Diarrhea|Child Development
Interventions: BEHAVIORAL: Water quality|BEHAVIORAL: Sanitation|BEHAVIORAL: Hand washing|BEHAVIORAL: Water quality, Sanitation, Hand washing (Combined WASH)|BEHAVIORAL: Nutrition|BEHAVIORAL: Nutrition, Water quality, Sanitation, Hand washing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: EndoBarrier Versus Intragastric Balloon in Obese Diabetic Patients
Status: UNKNOWN
Conditions: Type 2 Diabetes|Obesity
Interventions: DEVICE: EndoBarrier Gastrointestinal Liner|DEVICE: Easy life balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Belatacept to Delay Tacrolimus Initiation in Kidney Transplant Patients With Delayed Graft Function
Status: ACTIVE_NOT_RECRUITING
Conditions: Use of Belatacept in Kidney Transplant Patients
Interventions: BEHAVIORAL: impact of administering one dose of belatacept on Estimated Glomerular Filtration Rate(eGFR)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Therapeutic Horseback Riding in Children and Adolescents With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Child Development Disorders, Pervasive
Interventions: OTHER: Therapeutic horseback riding|OTHER: Barn Activity Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Prevention of Diabetes Mellitus Type 2 in Women Post Gestational Diabetes Mellitus Diagnosis
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus
Interventions: BEHAVIORAL: Lifestyle instruction for Jews and Bedouin GDM women.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of GS-9256 and GS-9190 Alone and in Combination With Ribavirin for 28 Days in Patients With Chronic Hepatitis C Virus Infection
Status: COMPLETED
Conditions: HCV Infection
Interventions: DRUG: GS-9256|DRUG: GS-9190|DRUG: Ribavirin|DRUG: Peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Dose of Radioactive Iodine Needed to Ablate the Thyroid Remnant Left Behind After Thyroidectomy
Status: UNKNOWN
Conditions: Thyroid Neoplasms
Interventions: DRUG: Radioactive iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined N-of-1 Trials to Assess Open-Label Placebo Treatment for Antidepressant Discontinuation Symptoms
Status: COMPLETED
Conditions: Depressive Symptoms|Expectations|Antidepressants
Interventions: DRUG: Open-label placebo|OTHER: No-treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility Study of the DragonFire for Hypertrophic Obstructive Cardiomyopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Obstructive Hypertrophic Cardiomyopathy
Interventions: DEVICE: DragonFire Transcatheter Myocardial Radiofrequency Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis and Pelvic Floor Muscle Strengthening Exercise Program In Patients With Grade 1 Cystocele
Status: COMPLETED
Conditions: Disability Physical|Urinary Incontinence|Prolapse
Interventions: OTHER: Pelvic floor muscle training|OTHER: Transverse abdominas strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Three Formulations of AGN-210669 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: AGN-210669 ophthalmic solution, 0.1%|DRUG: AGN-210669 ophthalmic solution, 0.075%|DRUG: AGN-210669 ophthalmic solution, 0.05%|DRUG: bimatoprost ophthalmic solution 0.03%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of PEG-uricase in the Treatment of Hyperuricemic Patients With Symptomatic Gout
Status: COMPLETED
Conditions: Gout
Interventions: OTHER: placebo|BIOLOGICAL: pegloticase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Two Formulations of Ondansetron in Healthy Adults (0869-106)
Status: COMPLETED
Conditions: Chemotherapy-Induced Nausea and Vomiting
Interventions: DRUG: ondansetron clinical trial formulation|DRUG: ondansetron marketed formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scaling up Schoolwide Positive Behavioral Interventions and Supports (SWPBIS) in Rural Idaho Schools
Status: COMPLETED
Conditions: Problem Behavior
Interventions: BEHAVIORAL: Idaho Rural Implementation Model|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Short-Burst Interval Treadmill Training Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: BEHAVIORAL: Short Burst Interval Treadmill Training (SBLTT)|BEHAVIORAL: Traditional Locomotor Treadmill Training (TLTT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improvement of Fatigue in Unstable Shoulder Through a Therapeutic Exercise Program in Physiotherapy
Status: RECRUITING
Conditions: Instability, Joint|Shoulder Dislocation|Fatigue|Therapeutic Alliance
Interventions: OTHER: MoveUS Program|OTHER: Control intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immune Responses in HIV-Positive Patients Receiving an Anti-HIV Drug Combination When Given the HIV Vaccines Remune and vCP1452
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: ALVAC(2)120(B,MN)GNP (vCP1452)|BIOLOGICAL: HIV-1 Immunogen
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Obstructive Sleep Apnea Therapy by Stimulation of the Hypoglossal Nerve
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DEVICE: Activated Inspire® Upper Airway Stimulation System|DEVICE: Inactivated Inspire® Upper Airway Stimulation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Rehabilitation Through Personalized Virtual Reality and Paper-and-pencil Interventions in the Alcohol Use Disorder Treatment.
Status: COMPLETED
Conditions: Alcohol Use Disorder (AUD)
Interventions: PROCEDURE: Virtual Reality|PROCEDURE: Paper and Pencil|PROCEDURE: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole Coffee Fruit Concentrate Pilot Study 1
Status: COMPLETED
Conditions: Brain-derived Neurotrophic Factor (BDNF)|Cognitive Function|Affect
Interventions: DIETARY_SUPPLEMENT: Whole Coffee Fruit Concentrate (WCFC)|DIETARY_SUPPLEMENT: Nutrim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: RASopathy Biorepository
Status: RECRUITING
Conditions: RAS Mutation|Neurofibromatosis 1|Noonan Syndrome|Noonan Syndrome With Multiple Lentigines|Noonan Neurofibromatosis Syndrome|Cardiofaciocutaneous Syndrome|Costello Syndrome|Legius Syndrome|Smith-Kingsmore Syndrome|MTOR Gene Mutation|GATOR-1 Gene Mutation|SYNGAP1-Related Intellectual Disability|DLG4|MAPK1 Gene Mutation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ghrelin Suppression by Octreotide in Prader-Willi
Status: ACTIVE_NOT_RECRUITING
Conditions: Prader Willis Syndrome
Interventions: DRUG: Placebo|DRUG: Octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Will Evaluate the Relative Bioavailability, Safety, and Tolerability of Single Doses of Nifurtimox 30 mg Tablets Exhibiting Different in Vitro Dissolution Characteristics, and to Evaluate the Relative Bioavailability of Nifurtimox 30 mg and 120 mg
Status: COMPLETED
Conditions: Chagas Disease
Interventions: DRUG: Nifurtimox (Lampit, BAYA2502)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of Oral PF-02341066, A C-Met/Hepatocyte Growth Factor Tyrosine Kinase Inhibitor, In Patients With Advanced Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer ALK-positive|Non-Small Cell Lung Cancer c-Met Dependent|Non-Small Cell Lung Cancer ROS Marker Positive|Systemic Anaplastic Large-Cell Lymphoma|Advanced Malignancies Except Leukemia
Interventions: DRUG: PF-02341066|DRUG: Rifampin|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy, Safety and Effect on Radiographic Progression of Brodalumab in Subjects With Psoriatic Arthritis
Status: TERMINATED
Conditions: Psoriatic Arthritis
Interventions: DRUG: 210 mg brodalumab|DRUG: 140 mg brodalumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Postural and Kinesthetic Awareness on Static Standing Balance in Stroke
Status: COMPLETED
Conditions: Chronic Stroke
Interventions: OTHER: Postural and Kinesthetic Awarness|OTHER: Routine Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Sorafenib and Omacetaxine Mepesuccinate in Newly Diagnosed or Relapsed/Refractory AML Carrying FLT3-ITD
Status: COMPLETED
Conditions: AML|FLT3-ITD Mutation
Interventions: DRUG: Sorafenib|DRUG: Omacetaxine Mepesuccinate Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sclerotherapy on Fistulas and Sinus Tracts in Hidradenitis Suppurativa
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: 23.4% Hypertonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of DTwP-HepB-Hib-IPV (SHAN6™) Vaccine Administered Concomitantly With Routine Pediatric Vaccines to Healthy Infants and Toddlers in Thailand
Status: COMPLETED
Conditions: Pertussis Immunisation|Diphtheria Immunisation|Polio Immunisation|Hepatitis B Immunisation|Haemophilus Influenzae Type B Immunisation|Tetanus Immunisation|Rotavirus Immunisation|Pneumococcal Immunisation
Interventions: BIOLOGICAL: DTwP-HepB-Hib-IPV hexavalent vaccine (Diphtheria toxoid, Tetanus toxoid, whole cell pertussis, Hepatitis B surface antigen (HBsAg), Haemophilus influenzae type b, inactivated poliovirus)|BIOLOGICAL: DTwP-HepB-Hib pentavalent vaccine (Diphtheria toxoid, Tetanus toxoid, whole cell pertussis, Hepatitis B surface antigen (HBsAg), Haemophilus influenzae type b)|BIOLOGICAL: Inactivated Poliomyelitis Vaccine|BIOLOGICAL: Poliomyelitis Vaccine bivalent types 1 and 3|BIOLOGICAL: Human Rotavirus, live attenuated|BIOLOGICAL: Pneumococcal polysaccharide conjugate vaccine (13-valent, adsorbed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Dose-Ranging Study of MK-1029 in Adults With Persistent Asthma (MK-1029-012)
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: MK-1029|DRUG: Montelukast 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of MInding the Baby in a Danish Community Sample
Status: ACTIVE_NOT_RECRUITING
Conditions: Family|Pregnancy, High Risk
Interventions: BEHAVIORAL: Minding the Baby|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deferasirox, Cholecalciferol, and Azacitidine in the Treatment of Newly Diagnosed AML Patients Over 65
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Deferasirox|DRUG: Cholecalciferol|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Twice Daily Oxycodone Hydrochloride Controlled-release Tablets in Children With Moderate to Severe Malignant and/ or Nonmalignant Pain Requiring Opioids
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Oxycodone HCl controlled-release tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Stem Cell Transplant in Treating Patients With Metastatic Kidney Cancer
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: fludarabine phosphate|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Middle Meningeal Artery Embolization for Treatment of Chronic Subdural Hematoma
Status: COMPLETED
Conditions: Chronic Subdural Hematoma
Interventions: PROCEDURE: Middel Meningeal Artery Embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Response of Anodal Transcranial Direct Current Stimulation Over the Cerebellar Hemisphere in Healthy Subjects
Status: COMPLETED
Conditions: Stroke|Transcranial Direct Current Stimulation|Functional Near Infrared Spectroscopy
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 50 mg /500 mg (FDC) in Healthy Adult Male and Female Subjects Under Fasting Conditions.
Status: COMPLETED
Conditions: Bioequivalence|Diabetes Mellitus, Type 2
Interventions: DRUG: Sitagliptin/Metformin HCl 50/500 mg extended release film-coated tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy Study of OMS721 in Patients With Atypical Hemolytic Uremic Syndrome
Status: RECRUITING
Conditions: Thrombotic Microangiopathies|Atypical Hemolytic Uremic Syndrome
Interventions: BIOLOGICAL: OMS721
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, Drug Levels and Drug Effects of BMS-986326 in Adult Participants With Different Forms of Lupus
Status: RECRUITING
Conditions: Lupus
Interventions: DRUG: BMS-986326|OTHER: Placebo for BMS-986326
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immune Monitoring to Facilitate Belatacept Monotherapy
Status: COMPLETED
Conditions: Kidney Transplant Rejection|Immunosuppression
Interventions: DIAGNOSTIC_TEST: Allosure|DRUG: Immunosuppression reduction|DIAGNOSTIC_TEST: Trugraf
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Thiazide Diuretics for Hypertension in Kidney Transplant Recipients Using Tacrolimus
Status: COMPLETED
Conditions: Hypertension|Kidney Transplantation
Interventions: DRUG: Chlorthalidone|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Healthy Subjects to Compare Two Tablet Formulations of Memantine (Ebixa®) in Fasted and Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lactose-free memantine|DRUG: Memantine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TCR Alpha/Beta and CD19-deplete Haplo-HSCT
Status: NOT_YET_RECRUITING
Conditions: Pediatric Patients|Hematologic Malignancy|Other Hematologic Condition
Interventions: DEVICE: CliniMACS Plus Instrument
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AZT Plus Ganciclovir in Patients With AIDS and Cytomegalovirus (CMV) Infection
Status: COMPLETED
Conditions: Cytomegalovirus Infections|HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Over-the-scope Clips and Standard Treatments in Endoscopic Control of Acute Bleeding From Non-variceal Upper GI Causes
Status: COMPLETED
Conditions: Acute Upper Gastrointestinal Bleeding|Tumor Bleeding
Interventions: DEVICE: Over-the-scope Clips|DEVICE: Hemo-clipping|DEVICE: thermo-coagulation|DRUG: Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of MEDI3506 in Healthy Participants, in Participants With COPD and Healthy Japanese Participants
Status: COMPLETED
Conditions: Part I (SAD) - Healthy Participants|Part II (MAD) - Chronic Obstructive Pulmonary Disease|Part III (J-SD) - Healthy Japanese Participants
Interventions: DRUG: MEDI3506|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Metyrapone for Mild Autonomous Cortisol Secretion (MACS)
Status: RECRUITING
Conditions: Autonomous Cortisol Secretion|Mild Autonomous Cortisol Secretion (MACS)
Interventions: DRUG: Metyrapone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison on Radiotherapy Permanent Skin Marking With Lancets and an Electric Marking Device
Status: UNKNOWN
Conditions: Radiotherapy|Tattooing
Interventions: DEVICE: Comfort Marker 2.0|DEVICE: Lancets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Essential Voice Tremor: A Study of Botulinum Toxin Treatment and Injection Augmentation
Status: COMPLETED
Conditions: Essential Tremor
Interventions: DRUG: RenuGel|DRUG: Botulinum Toxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Safety of Teriflunomide When Added to Interferon-Beta or Glatiramer Acetate in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Teriflunomide|DRUG: Placebo (for teriflunomide)|DRUG: Interferon-β [IFN-β]|DRUG: Glatiramer Acetate [GA]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Confirmatory Efficacy Trial of Attention Bias Modification for Depression
Status: NOT_YET_RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: Traditional Attention Bias Modification|BEHAVIORAL: Gamified Attention Bias Modification|BEHAVIORAL: Sham Attention Bias Modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Immune Response of 2 Doses of a New Shigella Vaccine in Kenyan Adults
Status: COMPLETED
Conditions: Shigella Sonnei Infection
Interventions: BIOLOGICAL: GVGH S. sonnei (1790GAHB) vaccine 25 μg|BIOLOGICAL: GVGH S. sonnei (1790GAHB) vaccine 100 μg|BIOLOGICAL: Menveo|BIOLOGICAL: Boostrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Randomized Trial Comparing Three-port and Single-port TEP Repair in Adults
Status: UNKNOWN
Conditions: Inguinal Hernia
Interventions: PROCEDURE: laparoscopic total extraperitoneal hernia repair (single port vs. multiport)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Interpersonal Therapy and Complicated Grief Treatment in Adults 50 Years and Older
Status: COMPLETED
Conditions: Complicated Grief
Interventions: BEHAVIORAL: Complicated Grief Treatment|BEHAVIORAL: Interpersonal Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study the Safety and Effectiveness of Tadalafil in Men With Problems Getting or Maintaining an Erection When Taken Prior to Desiring an Erection
Status: COMPLETED
Conditions: Impotence
Interventions: DRUG: tadalafil|DRUG: placebo|DRUG: tadalafil|DRUG: tadalafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fentanyl Use for Sedation in Esophagogastroduodenoscopy
Status: COMPLETED
Conditions: Endoscopy
Interventions: DRUG: Midazolam|DRUG: Fentanyl|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research Study to Investigate How Well Semaglutide Tablets Taken Once Daily Work in People Who Are Overweight or Living With Obesity (OASIS 1)
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DRUG: Oral semaglutide|DRUG: Placebo (semaglutide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Upper and Lower Respiratory Tract Infections in Young Children Using Probiotic
Status: COMPLETED
Conditions: Respiratory Infection (for Example, Pneumonia, Bronchitis)
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Steroid Resistance During COPD Exacerbations With Respiratory Failure
Status: UNKNOWN
Conditions: COPD|Emphysema or COPD|COPD Exacerbation|COPD Exacerbation Acute|Respiratory Failure|Ventilatory Failure
Interventions: DRUG: Methylprednisolone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Predicting Pain Response to Transcranial Direct Current Stimulation for Phantom Limb Pain in Limb Amputees
Status: COMPLETED
Conditions: Phantom Limb Pain
Interventions: DEVICE: transcranial Direct Current Stimulation (tDCS): (Soterix ©)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-IL-5 Therapy in Bullous Pemphigoid (BP)
Status: COMPLETED
Conditions: Pemphigoid, Bullous
Interventions: DRUG: Mepolizumab (a-IL-5 antibody)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BMS-247550 and Gemcitabine in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: gemcitabine hydrochloride|DRUG: ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Calcium Hypochlorite Versus Sodium Hypochlorite as Root Canal Irrigants on Postoperative Pain and Bacterial Reduction in Mandibular Premolars With Necrotic Pulps. .
Status: NOT_YET_RECRUITING
Conditions: Intervention
Interventions: OTHER: Calcium Hypochlorite as Root Canal Irrigant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Effect of Mindfulness-based Yoga on Youth With Persistent Concussion Symptoms
Status: COMPLETED
Conditions: Brain Concussion|Mild Traumatic Brain Injury
Interventions: BEHAVIORAL: Mindfulness-based Yoga Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Treatment of Extra-Corporeal Shock Wave Combined With aUtologous Bone marRow Mesenchymal Stem Cells on Patients With ischEmic Heart Disease : the S-CURE Study
Status: UNKNOWN
Conditions: Ischemic Heart Disease
Interventions: COMBINATION_PRODUCT: CSWT+BMMSCs|DEVICE: CSWT+Sham operation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endothelial Function and Autonomic Regulation After Short-term Smoking Cessation: Varenicline Versus Placebo
Status: TERMINATED
Conditions: Smoking
Interventions: DRUG: Varenicline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prophylaxis of Postoperative Nausea and Vomiting After Cardiac Surgery
Status: COMPLETED
Conditions: Postoperative Vomiting|Postoperative Nausea|Postoperative Emesis
Interventions: DRUG: Betamethasone|DRUG: Droperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: RAI Plus Immunotherapy for Recurrent/Metastatic Thyroid Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Thyroid Cancer
Interventions: DRUG: Durvalumab (Medi4736)|RADIATION: Radioiodine (RAI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tragal Perichondrium Versus Pretragal Fascial (SMAS) Graft for Endoscopic Myringoplasty
Status: UNKNOWN
Conditions: Tympanic Membrane Perforation
Interventions: PROCEDURE: Endoscopic myringoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vagus Nerve Stimulation in Fibromyalgia
Status: RECRUITING
Conditions: Fibromyalgia
Interventions: DEVICE: Vagus nerve stimulation|DRUG: Medical treatment|COMBINATION_PRODUCT: Combined vagus nerve stimulation and medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of SI-B001 Combined With Docetaxel in the Treatment of Non-small Cell Lung Adenocarcinoma and Lung Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Non-small Cell Lung Adenocarcinoma|Squamous Cell Carcinoma of Lung
Interventions: DRUG: SI-B001|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Ultrasound-guided Erector Spinae Plane Block for Postoperative Analgesia in Laparoscopic Sleeve Gastrectomy: A Prospective, Randomized, Controlled Clinical Trial
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Erector spinae block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing Early Enteral Nutrition Versus Parenteral Nutrition After Pancreaticoduodenectomy
Status: UNKNOWN
Conditions: Enteral Nutrition
Interventions: DIETARY_SUPPLEMENT: Total parenteral nutrition|DIETARY_SUPPLEMENT: Enteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized, Double-Blind Study of the Efficacy and Safety of Oral Ganciclovir for the Prevention of CMV Disease in People Infected With the Human Immunodeficiency Virus
Status: COMPLETED
Conditions: Cytomegalovirus Infections|HIV Infections
Interventions: DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Proximal Blood Flow Arrest During Endovascular Thrombectomy
Status: UNKNOWN
Conditions: Stroke|Occlusion, Cerebrovascular
Interventions: PROCEDURE: Endovascular thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Adrenocorticotropin Hormone to Treat Multiple Sclerosis (MS) Relapses After Sub-responding to an Initial 3 Day Course of Intravenous (IV) Methylprednisolone
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: DRUG: Methylprednisolone|DRUG: ACTH|OTHER: IV placebo|OTHER: IM placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Cyclosporine for Myocardial Protection During Open Heart Surgery
Status: TERMINATED
Conditions: Cardiac Surgical Procedures
Interventions: DRUG: cyclosporine|DRUG: saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study to Evaluate the Efficacy of XW003 in Adults With Overweight or Obesity
Status: ACTIVE_NOT_RECRUITING
Conditions: Weight Management
Interventions: DRUG: Ecnoglutide Low Dosage|DRUG: Ecnoglutide Medium Dosage|DRUG: Ecnoglutide High Dosage|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PRimary IndividualiZed Evaluation of Cardiovascular Events in Patients With Diabetes Mellitus Using hemoTAG
Status: RECRUITING
Conditions: Diabetes Mellitus Type 2|Cardiovascular Diseases|Coronary Artery Disease|Cerebrovascular Disease|Peripheral Artery Disease
Interventions: DEVICE: Hemotag
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Safety and Tolerability of Single-Dose Intravenous (IV) Oritavancin
Status: RECRUITING
Conditions: Acute Bacterial Skin and Skin Structure Infection
Interventions: DRUG: Oritavancin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROS-2 Dose Response Effects of Exogenous Testosterone on the Prostate
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: placebo acyline|OTHER: placebo gel|DRUG: Testosterone 1% gel 1.25 g|DRUG: Testosterone 1% gel 2.5 g|DRUG: Testosterone 1% gel 5.0 g|DRUG: testosterone 1% gel 10 g|DRUG: testosterone 1% gel 15 g|DRUG: Acyline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Safety and Immunogenicity Trial of UBI Multivalent HIV-1 Peptide Immunogen in HIV-1 Seronegative Human Subjects
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: HIV-1 Peptide Immunogen, Multivalent
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Clinical Study on the Re-irradiation of Lateral Pelvic Recurrences of Gynecological Malignancies
Status: RECRUITING
Conditions: Tumor Recurrence|Malignant Epithelial Neoplasm of Vulva|Malignant Epithelial Tumor of Ovary|Malignant Epithelial Neoplasm
Interventions: RADIATION: carbon ion radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release (XR) With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Canagliflozin and Metformin Extended Release (XR) Fixed Dose Combination [FDC]|DRUG: Canagliflozin|DRUG: Metformin Extended Release (XR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Adults With Attention Deficit Hyperactivity Disorder (ADHD): Validation of a Clinical Interview and Screening Instruments in French
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: OTHER: questionary|OTHER: questionary
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: ILM Flap Transposition Versus ILM Peeling for Macular Holes: a Pilot Study
Status: COMPLETED
Conditions: Macular Holes
Interventions: PROCEDURE: ILM flap transposition|PROCEDURE: ILM peeling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Status: NOT_YET_RECRUITING
Conditions: Heart Failure|Heart Diseases|Cardiovascular Diseases|Pulmonary Hypertension
Interventions: DEVICE: CardioMEMS HF System|DEVICE: HeartMate 3 Left Ventricular Assist System|OTHER: Guideline Medical Directed Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Ascending Oral Dose Study of SDI-118 in Healthy Male Subjects Including an Assessment of Receptor Occupancy and Food Effect
Status: COMPLETED
Conditions: Cognitive Disorders
Interventions: DRUG: SDI-118|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of TRIZIVIR (Abacavir/Lamivudine/Zidovudine) With Efavirenz in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: Abacavir sulfate, Lamivudine and Zidovudine|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Impact of Highly Effective Modulator Therapy on the Cystic Fibrosis Microbiome
Status: RECRUITING
Conditions: Cystic Fibrosis
Interventions: OTHER: Nasal endoscopy with microbiome swab and mucus collection through filter paper and sponge|OTHER: Olfactory Function Testing|OTHER: Survey Completion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Two Web-Based Education/Support Programs for Partner Caregivers of People With Spinal Cord Injury
Status: UNKNOWN
Conditions: Spinal Cord Injuries|Spinal Cord Diseases
Interventions: OTHER: Web-Based Support and Education Program 1|OTHER: Web-Based Support and Education Program 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Early Versus Traditional Follow-Up on Breastfeeding Rates at 6 Months
Status: COMPLETED
Conditions: Pregnancy|Breastfeeding|Contraception|Cervical Cancer|Postpartum Depression
Interventions: OTHER: Postpartum follow up appointment 2-3 weeks after delivery|OTHER: Postpartum follow up 6-8wk after delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Catheters Orifice Configuration For Continuous Infraclavicular Analgesia
Status: COMPLETED
Conditions: Pain, Postoperative|Catheter Blockage|Anesthesia
Interventions: PROCEDURE: CEMP (closed-ended multiport catheter) group|PROCEDURE: OESP (open-ended single port catheter) group|PROCEDURE: Patient-controlled analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Apexogenesis With Human Treated Dentin Matrix in Young Permanent Molars
Status: COMPLETED
Conditions: Dentin Bridge
Interventions: DRUG: human treated dentin matrix|DRUG: Mineral Trioxide Aggregate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Differential EFfects of Dual antIplatelet and Dual aNtithrombotic thErapy on Hemostasis in Chronic Coronary Syndrome Patients
Status: RECRUITING
Conditions: Thrombosis|Myocardial Infarction
Interventions: DRUG: Rivaroxaban|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Phenylephrine vs. Norepinephrine Infusion Undergoing Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: DRUG: Norepinephrine|DRUG: Phenylephrine|DRUG: Ringer's Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of AI-assisted cEEG Diagnosis on the Administration of Antiseizure Medication in Neonatal Seizures
Status: RECRUITING
Conditions: Neonatal Seizure
Interventions: OTHER: The routine assessment protocol and AI-assisted cEEG Diagnostic tool|OTHER: The routine assessment protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Diabetes Aerobic and Resistance Bands Exercise (DARE-Bands) Trial
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Aerobic Training (AT)|BEHAVIORAL: AT plus Primarily Home-Based Resistance Band Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sperm Production in Kleinfelter Syndrome Patients After Mesenchymal Stem Cell Injection
Status: COMPLETED
Conditions: Klinefelter Syndrome|Azoospermia
Interventions: DRUG: Mesenchymal stem cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Brinzolamide Dosed TID With Dorzolamide Dosed TID in Reducing Intraocular Pressure in Patients With Open Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: Azopt|DRUG: Cosopt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rigosertib Plus Pembrolizumab in Treating Patients With Unresectable/Metastatic Melanoma Refractory to PD-1 Inhibitors
Status: RECRUITING
Conditions: Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Metastatic Melanoma|Refractory Melanoma|Unresectable Melanoma
Interventions: DRUG: Rigosertib|BIOLOGICAL: Pembrolizumab|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Biospecimen Collection|PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability and Immunological Response of ASP2390 in Adult Subjects Allergic to House Dust Mites
Status: ACTIVE_NOT_RECRUITING
Conditions: Allergic to House Dust Mites
Interventions: BIOLOGICAL: ASP2390|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Empowering Mindfulness, Body Respect, and Compassionate Eating Among Women Who Binge Eat During Pregnancy
Status: SUSPENDED
Conditions: Pregnancy|Binge Eating
Interventions: BEHAVIORAL: Mindful Eating Self-Help Program|BEHAVIORAL: Mindful Eating Smartphone Application (Am I Hungry? Virtual Coach)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chart Review of the Efficacy of the GenesisPlus 1064 nm Nd:YAG Laser in the Treatment of Onychomycosis
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DEVICE: GenesisPlus 1064 nm Nd:YAG laser
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety and Effectiveness Study of Aroplatin in Patients With Advanced Solid Malignancies
Status: UNKNOWN
Conditions: Esophageal Neoplasms|Hepatocellular Carcinoma|Colorectal Neoplasms|Ovarian Neoplasms|Pancreatic Neoplasms|Neoplasms
Interventions: DRUG: Aroplatin (Liposomal NDDP, L-NDDP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supervised Aerobic Training During or After Chemotherapy for Operable Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Aerobic Training|BEHAVIORAL: Educational Information|BEHAVIORAL: Supervised Home Based Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 1 Trial of LVGN7409 (CD40 Agonist Antibody) as Single Agent and Combination Therapies in Advanced or Metastatic Malignancy
Status: RECRUITING
Conditions: Cancer
Interventions: BIOLOGICAL: LVGN7409
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Concordance Between Exhaled Air Test (eBAM-CoV) and RT-PCR to Detect SARS-CoV-2
Status: NOT_YET_RECRUITING
Conditions: SARS-CoV-2 Infection|COVID-19|Coronavirus
Interventions: DEVICE: eBAM Cov Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Investigating the Safety and Efficacy of SHR6508 Injection in the Treatment of Secondary Hyperparathyroidism in Hemodialysis Patients : A Multicenter, Long-term Clinical Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Secondary Hyperparathyroidism (SHPT) in Subjects With Chronic Kidney Disease (CKD) on Hemodialysis
Interventions: DRUG: SHR6508
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Among Children With Chronic Renal Diseases in Qatar
Status: COMPLETED
Conditions: Chronic Kidney Diseases|COVID-19 Infection|Acute Kidney Injury|Chronic Renal Failure in Children|COVID-19 Pandemic
Interventions: OTHER: Medical records review|OTHER: Medical records review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of AMG 330 in Combination With Pembrolizumab in Adult With Relapsed or Refractory Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Relapsed or Refractory Acute Myeloid Leukemia
Interventions: DRUG: AMG 330|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiomyopathy, Hypertrophic
Interventions: DRUG: Mavacamten|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT