pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Early Metabolic Resuscitation for Septic Shock
Status: TERMINATED
Conditions: Multiple Organ Failure|Septic Shock|Severe Sepsis
Interventions: OTHER: Best Practice|DIETARY_SUPPLEMENT: early metabolic resuscitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PET Quantitative Assessments of Solid Tumor Response to Immune Checkpoint Blockade Therapy
Status: COMPLETED
Conditions: Melanoma|Renal Cell Carcinoma (RCC)|Non-small Cell Lung Cancer (NSCLC)
Interventions: RADIATION: PET/CT imaging with [18F] 2-deoxy-2-(18F)fluoro-D-glucose (FDG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 2 Trial of OPC-64005 for Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: OPC-64005 20 mg , Once-daily|DRUG: OPC-64005 10 mg , Once-daily|DRUG: Placebo, Once-daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Insulin NovoRapid Versus Actrapid in Treatment of Type 1 Diabetic Patients During Daily Adjustment of Insulin Dose
Status: UNKNOWN
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Insulin NovoRapid versus Actrapid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: DV Combined With PD-1 and Platinum-based First-line Treatment in Patients With HER2 IHC2+/3+ ESCC
Status: NOT_YET_RECRUITING
Conditions: Esophageal Squamous Carcinoma|HER-2 Protein Overexpression
Interventions: DRUG: RC48+PD-1+platinum-based
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Echography-guided Surfactant THERapy (ESTHER) For Preterm Infants With Respiratory Failure
Status: RECRUITING
Conditions: Respiratory Distress Syndrome, Newborn|Pulmonary Surfactants|Intensive Care Units, Neonatal
Interventions: DIAGNOSTIC_TEST: Echography-guided Surfactant THERapy (ESTHER)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-FISETIN: Pilot in SARS-CoV-2 of Fisetin to Alleviate Dysfunction and Inflammation
Status: ENROLLING_BY_INVITATION
Conditions: Covid19
Interventions: DRUG: Placebo|DRUG: Fisetin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of Reduced Impedance Noninvasive Cortical Electrostimulation (RINCE) to Reduce Fibromyalgia Effects - Extension Study
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DEVICE: RINCE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigational Immunotherapy Study of BMS-986299 Alone and in Combination With Nivolumab and Ipilimumab in Participants With Solid Cancers That Have Spread or Cannot be Removed
Status: TERMINATED
Conditions: Advanced Cancer
Interventions: DRUG: BMS-986299|BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Data Collection of Arterial Line Waveform and BP Values
Status: COMPLETED
Conditions: Blood Pressure Measurement
Interventions: DEVICE: Arterial catheterization kit|DEVICE: GE Datex-Ohmeda Finger Clip Pulse Oximeter Sensor|DEVICE: NIBP Cuff (GE Healthcare)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BioDulse II: The Effect of an Irish Seaweed Protein Extract on Glucose Control in Adults With Type 2 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Seaweed protein|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The RAPID Trial: Assessing Point-of-care Influenza and Other Respiratory Virus Diagnostics
Status: COMPLETED
Conditions: Respiratory Pathogens|Upper Respiratory Tract Illness|Lower Respiratory Tract Illness|Acute Respiratory Infection
Interventions: DIAGNOSTIC_TEST: Results available to provider
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: BodyPump and Personal Training - Changes in Muscle Strength and Body Composition
Status: COMPLETED
Conditions: Overweight
Interventions: OTHER: BodyPump|OTHER: Personal training|OTHER: Resistance training with instructor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Reflexology Massage and Passive Music Therapy Intervention Before Burn Dressing
Status: COMPLETED
Conditions: Burn Degree Second|Burn Degree Third
Interventions: OTHER: Reflexology massage|OTHER: Reflexology massage and passive music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Excipient Effect on Drug Absorption in Humans
Status: RECRUITING
Conditions: The Impact of Excipients on Drug Absorption
Interventions: DRUG: Fexofenadine Hydrochloride without sodium lauryl sulfate|DRUG: Fexofenadine Hydrochloride with sodium lauryl sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact of Dynamic Neuromuscular Stabilization on Pregnancy
Status: RECRUITING
Conditions: Pregnant|Exercise
Interventions: BEHAVIORAL: Dynamic Neuromuscular Stabilization|BEHAVIORAL: Standard Prenatal Education Program Implementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Brain Natriuretic Peptide Effects on Appetite Regulating Hormones and Endothelial Derived Peptides
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BNP|DRUG: 0.9% NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Comparing Misoprostol and Oxytocin in Uniject for Postpartum Hemorrhage (PPH) Prevention in Senegal
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Misoprostol|DEVICE: UnijectTM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multicenter,Single-arm Study to Evaluate Efficacy, Safety, & Pharmacokinetics of Denosumab in Children w/ OI
Status: TERMINATED
Conditions: Osteogenesis Imperfecta
Interventions: DRUG: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Performance, Usability, and Result Interpretation of INSTI® HIV Self-Test
Status: RECRUITING
Conditions: Human Immunodeficiency Virus I Infection|Human Immunodeficiency Virus II Infection
Interventions: DEVICE: INSTI® HIV Self-Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: An Open-label, Multicenter, Prospective Study of Irreversible Electroporation (Nano Knife) Combined With Radiotherapy and Chemotherapy in Patients With Locally Advanced Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer|Locally Advanced Pancreatic Caner
Interventions: PROCEDURE: Irreversible electroporation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Renin Inhibition on Fibrinolytic Balance and Endothelial Function
Status: COMPLETED
Conditions: High Blood Pressure
Interventions: DRUG: Aliskiren 150 mg|DRUG: Placebo|DRUG: HCTZ|DRUG: Aliskiren 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase I/II Study of Abraxane in Recurrent and Refractory Lymphoma
Status: TERMINATED
Conditions: Lymphoma, Non-Hodgkin|Hodgkin Disease
Interventions: DRUG: Abraxane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ENB Guided MWA Combined With VATS Versus Sequential Surgery for Synchronous Bilateral Multiple Primary Lung Nodules
Status: RECRUITING
Conditions: Multiple Primary Lung Cancer
Interventions: PROCEDURE: ENB guided MWA combined with VATS|PROCEDURE: sequential surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vegetables Intake and Polymorphism TAS2R38 Gene by Healthy Adults
Status: COMPLETED
Conditions: Healthy Lifestyle|Taste Disorders|Diet Habit
Interventions: BEHAVIORAL: Intervention genotype personalized nutritional recommendations|BEHAVIORAL: Control Group 1 personalized nutritional recommendations|BEHAVIORAL: Control Group 2 general nutritional recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pelvic Floor Muscle Training With a Digital Therapeutic Device to Standard Exercises for Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: Leva Pelvic Digital Health System|OTHER: Kegel exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Venous Drainage in Idiopathic Intracranial Hypertension
Status: RECRUITING
Conditions: Intracranial Hypertension
Interventions: DIAGNOSTIC_TEST: MRI examination|DIAGNOSTIC_TEST: ECG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating the Hunger Project in Ghana
Status: UNKNOWN
Conditions: To Better Understand How Epicenter's (Which House Education, Health and Finance Centers in Ghana) Increase Individual's Sense of Empowerment.
Interventions: BEHAVIORAL: Community Empowerment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Short Course of Miltefosine and Antimony to Treat Cutaneous Leishmaniasis in Bolivia
Status: UNKNOWN
Conditions: Cutaneous Leihmaniasis
Interventions: DRUG: Miltefosine , meglumine antimoniate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Simplification Study to Lopinavir/Ritonavir 800/200 mg Monotherapy Regimen Once Daily
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Lopinavir/ritonavir 800 mg / 200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Bacteriuria in Renal Transplantation (BiRT) Study: A Trial Comparing Antibiotics Versus no Treatment in the Prevention of Symptomatic Urinary Tract Infection in Kidney Transplant Recipients With Asymptomatic Bacteriuria
Status: COMPLETED
Conditions: Asymptomatic Bacteriuria|Bacteriuria|Urinary Tract Infections|Kidney Transplantation
Interventions: OTHER: Anti-Infective Agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of UNICLA-A2 Dairy Products on Patients at High-risk of Colorectal Cancer Development
Status: RECRUITING
Conditions: Colorectal Polyp
Interventions: DIETARY_SUPPLEMENT: Milk from genetically selected homozygous- β-casein-A2 cows fed with forages and a concentrate enriched on linseed and selenized yeast as sources of PUFAs and selenium|DIETARY_SUPPLEMENT: Conventional milk|DIETARY_SUPPLEMENT: Yogurt made from milk of genetically selected homozygous- β-casein-A2 cows fed with forages and a concentrate enriched on linseed and selenized yeast as sources of PUFAs and selenium|DIETARY_SUPPLEMENT: Conventional yogurt|DIETARY_SUPPLEMENT: Fresh cheese made from milk of genetically selected homozygous- β-casein-A2 cows fed with forages and a concentrate enriched on linseed and selenized yeast as sources of PUFAs and selenium|DIETARY_SUPPLEMENT: Conventional fresh cheese
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Influence of Polishing After Bleaching on Color Change and Enamel Morphology
Status: COMPLETED
Conditions: Tooth Discoloration|Morphologic Change|Tooth Sensitivity
Interventions: OTHER: Hydrogen Peroxide 35%|OTHER: Hydrogen Peroxide 35% + Polishing whitened teeth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Comparing Music Therapy and Cognitive Behavioral Therapy for Anxiety in Cancer Survivors
Status: RECRUITING
Conditions: Survivorship
Interventions: OTHER: Music Therapy|OTHER: Cognitive Behavioral Therapy|OTHER: assessments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cryotherapy With in Situ Immunotherapy in Melanoma Metastasis
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: DRUG: Nivolumab 10 MG/ML Intravenous Solution [OPDIVO]|PROCEDURE: Cryotherapy|DRUG: Ipilimumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: EDWARDS INTUITY Valve System CADENCE-MIS Study
Status: COMPLETED
Conditions: Aortic Valve Disease|Aortic Stenosis
Interventions: DEVICE: EDWARDS INTUITY Valve System, Model 8300A|DEVICE: Stented Aortic Bioprostheses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade Glioma
Status: RECRUITING
Conditions: Diffuse Glioma|Malignant Glioma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Eflornithine|PROCEDURE: Magnetic Resonance Imaging|DRUG: Polyamine Transport Inhibitor AMXT-1501 Dicaprate|PROCEDURE: Resection|DEVICE: Microdialysis|PROCEDURE: Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Endorectal Coil Magnetic Resonance Images (ERC-MRI)
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: PROCEDURE: Endorectal Coil Magnetic Resonance Images
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: BonE and Joint Infections - Simplifying Treatment in Children Trial
Status: RECRUITING
Conditions: Bone Infection|Septic Arthritis|Bone and Joint Infection|Osteomyelitis
Interventions: DRUG: Oral cefalexin only|DRUG: IV cefazolin or IV flucloxacillin followed by oral cefalexin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent B Acute Lymphoblastic Leukemia
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Asparaginase|BIOLOGICAL: Blinatumomab|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Dexamethasone|DRUG: Etoposide|DRUG: Leucovorin Calcium|DRUG: Mercaptopurine|DRUG: Methotrexate|DRUG: Mitoxantrone|DRUG: Mitoxantrone Hydrochloride|DRUG: Pegaspargase|OTHER: Pharmacological Study|RADIATION: Radiation Therapy|DRUG: Therapeutic Hydrocortisone|DRUG: Thioguanine|DRUG: Vincristine|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Atropine for Treatment of Myopia
Status: COMPLETED
Conditions: Myopia
Interventions: DRUG: Atropine|OTHER: Placebo Eyedrops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Re-licensing Study to Assess the Efficacy of Inflexal V Formulated With WHO Recommended 2009/2010 Influenza Virus Strains for the Northern Hemisphere
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Inflexal V
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Direct E-test on Bronchoalveolar Lavage From Patients With Ventilator-acquired Pneumonia
Status: COMPLETED
Conditions: Ventilator Acquired Pneumonia
Interventions: PROCEDURE: E test|PROCEDURE: standard culture method
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Irinotecan Liposome Injection as Second-line Regimen in Patients With Small Cell Lung Cancer (SCLC)
Status: COMPLETED
Conditions: Small Cell Lung Cancer (SCLC)
Interventions: DRUG: irinotecan liposome injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality (VR) Therapy for Post-Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: Treatment as Usual|BEHAVIORAL: Virtual Reality Exposure with Stimulus Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Vortioxetine (Lu AA21004) in Major Depressive Disorder in Asian Countries
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Vortioxetine (Lu AA21004)|DRUG: Venlafaxine extended release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Pharmacokinetics and Safety of Dupilumab in Participants ≥6 Months to <18 Years of Age With Prurigo Nodularis
Status: RECRUITING
Conditions: Prurigo Nodularis
Interventions: DRUG: Dupilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Watching Video and Blowing Paper Pinwheels in Children
Status: NOT_YET_RECRUITING
Conditions: Pain|Fear
Interventions: BEHAVIORAL: Video-watching|BEHAVIORAL: Blowing Pinwheels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Feasibility of Telehealth HEP for CP (HEP: Home Exercise Program), (CP: Cerebral Palsy)
Status: UNKNOWN
Conditions: Cerebral Palsy, Spastic|Telemedicine
Interventions: BEHAVIORAL: Telehealth home exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Nd:YAG Laser Vitreolysis for Symptomatic Vitreous Floaters
Status: RECRUITING
Conditions: Weiss Ring
Interventions: PROCEDURE: YAG vitreolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pulsed-field Gel Electrophoresis and Whole Genome Sequencing to Determine Transmission Rate of ESBL-producing E.Coli
Status: ENROLLING_BY_INVITATION
Conditions: Analysis Transmission Rate
Interventions: DIAGNOSTIC_TEST: Pulsed-field gel electrophoresis and whole genome sequencing|OTHER: Data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Patient Palatability and Preference of 3 Potassium Binders in Patients With Chronic Kidney Disease and Hyperkalaemia
Status: COMPLETED
Conditions: Chronic Kidney Disease + Hyperkalaemia +/- Heart Failure
Interventions: DRUG: Calcium Polystyrene Sulphonate 15g/60 mL water|DRUG: Lokelma® 5 g/45mL water|DRUG: Lokelma® 10 g/45 mL water|DRUG: Veltassa® 8,4 g/80mL water|DRUG: Sodium Polystyrene Sulphonate 15g/60 mL water
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Endoscopic Treatment of Intestinal Fistulas and Perforations
Status: UNKNOWN
Conditions: Gastrointestinal Fistula|Gastrointestinal Perforation
Interventions: PROCEDURE: endoscopic closure of gastrointestinal fistulas and perforations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Fentanyl Consumption Guided by Analgesia Nociception Index
Status: COMPLETED
Conditions: Postoperative Pain|Postoperative Complications
Interventions: PROCEDURE: Standard protocol|PROCEDURE: ANI protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Apatinib as Third-line Therapy for Primary Pulmonary Lymphoepithelioid Carcinoma
Status: UNKNOWN
Conditions: Lung Carcinoma
Interventions: DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Mechanistic Evaluation of the Interactions Between Thermoceptive and Pruriceptive Sensory Processing
Status: COMPLETED
Conditions: Itch|Thermal Stimulation|Histamine|Cowhage|Serotonine
Interventions: DRUG: Lidocaine|OTHER: Histamine|OTHER: Cowhage|OTHER: Heat stimulation|OTHER: Pre-heating|OTHER: Serotonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigation of the Effectiveness of Group Voice Therapy in Children
Status: RECRUITING
Conditions: Dysphonia
Interventions: BEHAVIORAL: Group Voice Therapy|BEHAVIORAL: Individual Voice Therapy|BEHAVIORAL: Vocal Hygiene Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Human Milk Bank in the Protection of Severe Respiratory Disease in Very Low Birth Weight Premature Infants
Status: COMPLETED
Conditions: Respiratory Infections
Interventions: DIETARY_SUPPLEMENT: Human donor milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Use of ACE Inhibitors in the Early Renal Post-transplant Period
Status: COMPLETED
Conditions: Renal Transplant
Interventions: DRUG: enalapril|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemoprevention of Prostate Cancer, HDAC Inhibition and DNA Methylation
Status: COMPLETED
Conditions: Prostate Cancer Prevention
Interventions: DRUG: SFN-rich broccoli sprout extract capsules|DIETARY_SUPPLEMENT: Gelatin capsule containing microcrystalline cellulose.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Incidental Findings Information on Lung Cancer Screening Intent
Status: COMPLETED
Conditions: Neoplasm of Lung|Decision Support Techniques|Mass Screening
Interventions: BEHAVIORAL: Lung Cancer Screening Decision Aid with Incidental Findings Information|BEHAVIORAL: Lung Cancer Screening Decision Aid without Incidental Findings Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Efficacy of FWGE in Combination With Hormone Therapy for the Treatment of Hormone-Refractory Prostate Cancer Patients
Status: UNKNOWN
Conditions: Hormone Refractory Prostate Cancer
Interventions: DRUG: Fermented Wheat germ extract
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resin Bulkfill Dual-Cured of Proximal Restoration. Clinical Trial
Status: COMPLETED
Conditions: Dental Restoration|Dental Caries
Interventions: PROCEDURE: Restoration teeth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Treatment-Sparing Effects of AEROVANT™ AER 001 Inhalation Powder in Asthma Patients, AEROTRIAL
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Aerovant|DRUG: Aerovant|DRUG: Aerovant|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between the Axillary Bilateral-breast Approach (ABBA) and Bilateral Axillo-breast Approach (BABA) for Robotic Thyroidectomy
Status: COMPLETED
Conditions: Thyroid Papillary Carcinoma|Thyroidectomy
Interventions: PROCEDURE: The Axillary Bilateral-breast Approach|PROCEDURE: The bilateral Axillo-breast Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Acetylcysteine/Doxofylline 1200/400 mg Effervescent Tablet in the Treatment of Moderate-Severe COPD.
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Acetylcysteine/Doxofylline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Construction of Molecular Diagnostic Marker Model for Pancreatic Cystic Tumors Based on Pancreatic Cystic Fluid Samples
Status: RECRUITING
Conditions: Pancreatic Neoplasms|DNA Methylation|Proteome
Interventions: DIAGNOSTIC_TEST: cfDNA methylation sequencing and proteome analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pemetrexed and S-1 in Combination With Bevacizumab in Refractory Colorectal Cancer
Status: WITHDRAWN
Conditions: Colorectal Neoplasms
Interventions: DRUG: Pemetrexed|DRUG: S-1|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Gongs Mobilization and Scapular Mobilization on Adhesive Capsulitis
Status: UNKNOWN
Conditions: Adhesive Capsulitis
Interventions: OTHER: Gongs mobilization|OTHER: scapular mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter, Prospective, Randomized, Controlled, Double-blind Trial on the Impact of Rosuvastatin on Subclinical Markers of Atherosclerosis in Patients With Primary Necrotizing Vasculitides
Status: COMPLETED
Conditions: ANCA-associated Primary Necrotizing Vasculitides
Interventions: DRUG: Rosuvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability and Pharmacokinetics of Liraglutide-depot in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2|Healthy
Interventions: DRUG: liraglutide-depot|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PXD101 as Second-Line Therapy in Treating Patients With Malignant Mesothelioma of the Chest That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Advanced Malignant Mesothelioma|Epithelial Mesothelioma|Recurrent Malignant Mesothelioma|Sarcomatous Mesothelioma
Interventions: DRUG: belinostat|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of a Digitally Based Multidomain Intervention for Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: Digitally based multidomain intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Novel Audit and Feedback Bundle on Inpatient Performance
Status: COMPLETED
Conditions: Quality Improvement
Interventions: OTHER: Audit and Feedback Bundle|OTHER: Bi-weekly audit and feedback emails
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PreOperative Endocrine Therapy for Individualised Care With Abemaciclib
Status: RECRUITING
Conditions: Breast Cancer Female
Interventions: DRUG: Abemaciclib|DRUG: Endocrine therapy (letrozole, anastrozole, exemestane or tamoxifen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fruquintinib and Pirfenidone in Combination With Anti-PD-1 Antibody in Advanced or Metastatic pMMR/MSS Colorectal Carcinoma
Status: NOT_YET_RECRUITING
Conditions: To Evaluate the Efficacy of Fruquintinib and Pirfenidone in Combination With Anti-PD-1 Antibody in Colorectal Carcinoma|To Evaluate Whether Pirfenidone Can Reshape the Tumor Microenvironment in Colorectal Cancer|Combination of Fruquintinib and Anti-PD-1 Antibody Was Reported to Improve Patient Prognosis in Colorectal Cancer
Interventions: DRUG: Pirfenidone|DRUG: Fruquintinib|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Recombinant LH in Patients With Repeated Implantation Failure
Status: COMPLETED
Conditions: Female Infertility|Female Subfertility
Interventions: DRUG: rFSH + r-LH in combination|DRUG: rFSH alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Bariatric Surgery on the Evolution of Nonalcoholic Fatty Liver Disease: a Comparative Clinical Trial Between Sleeve Gastrectomy and Gastric Bypass
Status: COMPLETED
Conditions: Obesity|Fatty Liver
Interventions: DEVICE: Transient hepatic elastography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Window of Opportunity Trial, PARP Inhibitor Rucaparib Affect on PD-L1 Expression in Triple Negative Breast Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Rucaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VICTOR Study - A Study of Valcyte (Valganciclovir po) Compared to Ganciclovir iv in Patients With Cytomegalovirus (CMV) Disease Who Are Solid Organ Transplant Recipients
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: DRUG: Ganciclovir|DRUG: valganciclovir [Valcyte]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of SHR-A1912 Combined With Other Therapies in B-cell Non-Hodgkin 's Lymphoma
Status: RECRUITING
Conditions: B-cell Non-Hodgkin's Lymphoma
Interventions: DRUG: SHR-A1912; R-Chemo|DRUG: SHR-A1912; R-Chemo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brainsway DTMS for Treatment of MDD Using iTBS
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: Brainsway DTMS with intermittent Theta Burst Stimulation (iTBS)|DEVICE: Brainsway DTMS with High Frequency (HF) Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of tDCS for Mild to Moderate Alzhemier's Disease
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: DEVICE: Yband (YDT-201N)|DEVICE: sham-Yband (YDT-201N)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lesinurad/Allopurinol 200/300 FDC Tablets Bioavailability
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: lesinurad/allopurinol 200/300 FDC tablets|DRUG: lesinurad 200 mg|DRUG: allopurinol 300 mg|DRUG: lesinurad/allopurinol 200/200 FDC tablets|DRUG: allopurinol 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tropisetron on Postoperative Pain
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Group P+P|DRUG: Group P+T|DRUG: Group S+P|DRUG: Group S+T
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Biological Standarization of Cupressus Arizonica Allergen Extract to Determine the Biological Activity in Histamine Equivalent Units (HEP)
Status: COMPLETED
Conditions: Allergy to Tree Pollen
Interventions: BIOLOGICAL: Cupressus arizonica
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Childbirth Performed in Collaboration With Midwife-Pregnant
Status: RECRUITING
Conditions: Birth, First|Care Pattern, Maternal|Care|Pregnancy Related
Interventions: OTHER: Midwifery care applied in line with Midwife-Pregnant cooperation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Efficacy of Manual Therapy, Therapeutic Exercise and the Two Modalities Combined in Pain Reduction in Patients With Headache
Status: RECRUITING
Conditions: Headache
Interventions: OTHER: Myofascial Release (MR)|DRUG: clinical practice drug treatment|OTHER: Manual therapy (MT)|OTHER: Therapeutic exercise (TE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanistic Clinical Trial of PCSK9 Inhibition for AAA
Status: NOT_YET_RECRUITING
Conditions: Abdominal Aortic Aneurysm
Interventions: DRUG: Evolocumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Acetylcysteine in the Prevention of Renal Failure After Bypass Surgery
Status: COMPLETED
Conditions: Kidney Failure
Interventions: DRUG: N-Acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Immunogenicity of the HIV gp120-NefTat/AS01B Vaccine (GSK SB732461)
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus|HIV Infections
Interventions: PROCEDURE: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase I Safety and Immunogenicity Trial of UBI HIV Lipopeptide Immunotherapeutic P3C541b in HIV-1 Seropositive Human Subjects
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: P3C541b Lipopeptide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Novel Diagnostic Techniques for Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis|Knee Injuries
Interventions: OTHER: Intra-articular ultrasound imaging of knee joint during arthroscopy|OTHER: Non-invasive ultrasound imaging of knee|OTHER: Quantitative MRI imaging of knee|OTHER: Contrast-enhanced CT imaging of knee
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of S-1 Oxaliplatin (SOX) for Biliary Tract Cancer (BTC) (Ampullary Adenocarcinoma)
Status: UNKNOWN
Conditions: Biliary Tract Cancer
Interventions: DRUG: S-1 oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Limb Remote Ischemic Conditioning and Cerebrovascular Reserve
Status: UNKNOWN
Conditions: Ischemic Cerebrovascular Disease
Interventions: DEVICE: Limb remote ischemic conditioning|DEVICE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: YUKON Choice Versus TAXUS Liberté in Diabetes Mellitus
Status: COMPLETED
Conditions: Coronary Arteriosclerosis
Interventions: DEVICE: Yukon Choice stent system|DEVICE: Taxus Liberté stent system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of Autologous Umbilical Cord Blood Reinfusion in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|CP|Spastic Cerebral Palsy
Interventions: BIOLOGICAL: Autologous UCB Reinfusion|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Adalimumab in Mucopolysaccharidosis Types I, II and VI
Status: COMPLETED
Conditions: Mucopolysaccharidosis Type I|Mucopolysaccharidosis Type II|Mucopolysaccharidosis Type VI
Interventions: DRUG: Adalimumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AK104 in Locally Advanced MSI-H/dMMR Gastric Carcinoma and Colorectal Cancer
Status: UNKNOWN
Conditions: MSI-H/dMMR Gastric Carcinoma and Colorectal Cancer
Interventions: DRUG: AK104
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Group-based [ADAPT] Versus One-to-one [Usual] Occupational Therapy: A Pilot and Feasibility Study
Status: COMPLETED
Conditions: Chronic Condition|Chronic Conditions, Multiple
Interventions: OTHER: ADAPT program|OTHER: UOT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparing IM vs. Vaginal Progesterone for Pre-term Birth
Status: COMPLETED
Conditions: Infant, Premature|Premature Birth
Interventions: DRUG: Intramuscular Progesterone|DRUG: Vaginal Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Investigate the Effectiveness of a Dietary Supplement in Increasing Libido and Sexual Function in Postmenopausal Women.
Status: UNKNOWN
Conditions: Female Sexual Arousal Disorder
Interventions: DIETARY_SUPPLEMENT: Tribulus Terrestris|OTHER: Placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BrUOG 278: FOLFOX-A For Pancreatic Cancer A Brown University Oncology Research Group Study
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Dose level 1|DRUG: Dose level 2/MTD|DRUG: Dose level 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Anti-TNF (Alpha) Treatment on Vascular Stiffness in Ankylosing Spondylitis (AS)
Status: COMPLETED
Conditions: Ankylosing Spondylitis(AS)
Interventions: DRUG: Simponi|OTHER: 0.9ml sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Functional Outcomes After Bilateral, 3D Ultrasound-guided Focal Thermal Ablation of the Prostate Transition Zone, in Patients With Benign Prostatic Hyperplasia-related Obstruction
Status: NOT_YET_RECRUITING
Conditions: Benign Prostatic Hyperplasia
Interventions: PROCEDURE: Targeted Microwave Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single and Multiple Ascending Dose Trial of CVL-354 in Healthy Participants
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Drug: CVL-354|DRUG: Drug: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Antiviral Activity of Inarigivir Soproxil (Formerly: GS-9992) Plus Tenofovir Alafenamide (TAF) for 12 Weeks in Adults With Chronic Hepatitis B (CHB)
Status: TERMINATED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Inarigivir Soproxil|DRUG: TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Treatment for Chronic Pain Combining Neuromodulation, Computer Assisted Training and Telemonitoring
Status: NOT_YET_RECRUITING
Conditions: Pain
Interventions: COMBINATION_PRODUCT: tDCS+EuleriaLab|DEVICE: tDCS|OTHER: EuleriaLab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The ReTAVI Prospective Observational Registry
Status: RECRUITING
Conditions: Structural Valve Deterioration|Structural Valve Degeneration|Symptomatic Patients Who Have Had Transcatheter Heart Valve (THV) Failure|Prosthetic Valve Malfunction|Prosthesis Failure
Interventions: PROCEDURE: Elective redo transcatheter aortic valve implantation (redo-TAVI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Efficacy of Sertraline Augmented With Gabapentin in Depressed, Recently Abstinent Cocaine-dependent Humans
Status: COMPLETED
Conditions: Cocaine Dependence|Depressive Symptoms
Interventions: DRUG: sertraline|DRUG: Placebo|DRUG: gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Air-plasma Flow and Nitric Oxide Therapy in Cardiac Surgery
Status: COMPLETED
Conditions: Mediastinitis
Interventions: PROCEDURE: NO-based treatment of sterno-mediastinitis|PROCEDURE: Treatment of sterno-mediastinitis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Nasal Airflow Parameters After Septoplasty and Turbinoplasty
Status: COMPLETED
Conditions: Nasal Obstruction|Nasal Septum; Deviation|Nasal Mucosa Hypertrophy
Interventions: DIAGNOSTIC_TEST: Rhinomanometry in patients after septoplasty and/or turbinoplasty|DIAGNOSTIC_TEST: Acoustic rhinometry in patients after septoplasty and/or turbinoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Dry Needling and Ischemic Compression in Sternocleidomastoid, on Cervical Motor Control in Patients With Cervical Pain.
Status: COMPLETED
Conditions: Cervical Pain
Interventions: OTHER: Dry Needling and Ischemic Compression at the Trigger Point|OTHER: Dry Needling and Ischemic Compression at 1.5 centimeters from the Trigger Point
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Effect of Whole Body Vibration on Diabetics and Non-diabetics
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: whole body vibration em DM|OTHER: Vibration "sham" em DM|OTHER: whole body vibration em NDM|OTHER: Vibration "sham" em NDM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Individualized Versus Conventional Perioperative Blood Pressure Management
Status: RECRUITING
Conditions: Major Non-cardiac Surgery
Interventions: OTHER: Individualized perioperative blood pressure management strategy|OTHER: Conventional perioperative blood pressure management strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: THIODERM ELATE for Volume Augmentation in Lips
Status: NOT_YET_RECRUITING
Conditions: Lip; Anomaly
Interventions: DEVICE: THIODERM ELATE|DEVICE: Juvéderm Ultra 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT