pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Phase I, Bioequivalence Study to Evaluate Two Formulations of Bendamustine (BDM) Hydrochloride (HCl) Administered to Cancer Patients
Status: COMPLETED
Conditions: Cancer Which Has Either Progressed or Relapsed After Standard Therapy, or for Which no Curative or Standard Therapy is Appropriate
Interventions: DRUG: Test Product (Bendamustine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Optimizing Tattoo Removal: a Side-by-side Comparison in the Search for One Treatment Tattoo Removal
Status: COMPLETED
Conditions: Tattoo|Tattoo Removal
Interventions: PROCEDURE: Tattoo Removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic-pharmacodynamic Analysis of Sugammadex in Children
Status: COMPLETED
Conditions: Anesthesia, General|Neuromuscular Blockade
Interventions: DRUG: Sugammadex Injection 2mg/kg|DRUG: Sugammadex Injection 4mg/kg|DRUG: Sugammadex Injection 8mg/kg|DRUG: Neuromuscular reversal agent injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Relative Bioavailability Study of a Fixed-dose Combination Dolutegravir/Abacavir/Lamivudine Dispersible Tablet
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: DTG/ABC/3TC FDC DISPERSIBLE TABLET|DRUG: EPZICOM (ABC/3TC)|DRUG: TIVICAY (DTG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening of Obstructive Sleep Apnea Syndrome in Patients With Resistant Systemic Arterial Hypertension: Pilot Study
Status: UNKNOWN
Conditions: Sleep Apnea, Obstructive|Resistant Hypertension
Interventions: DEVICE: type IV portable monitoring (Somnocheck micro Weinmann)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Conventional vs. Video-Assisted Laryngoscopy for Perioperative Endotracheal Intubation
Status: RECRUITING
Conditions: Endotracheal Intubation
Interventions: PROCEDURE: Conventional direct laryngoscopy (CDL)|PROCEDURE: Video assisted laryngoscopy with Macintosh-shaped blade (M-VAL)|PROCEDURE: Video assisted laryngoscopy with hyper-angulated blade (H-VAL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pharmacokinetic, Safety and Tolerability Study of Aclidinium/Formoterol Fixed Dose Combination and Formoterol in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Aclidinium/formoterol 400/12μg|DRUG: Formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reproducibility and Comparison of Platelet Function Assays With Aspirin and Clopidogrel (MK-0000-167)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Placebo (to match Aspirin)|DRUG: Aspirin|DRUG: Clopidogrel|DRUG: Comparator: Placebo (to match Clopidogrel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Increased Circulating Androgens on Granulosa Cell Responses to FSH.
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy, Safety, & Tolerability of AZD3480 Patients With Mild to Moderate Dementia of the Alzheimer's Type (AD)
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Donepezil|DRUG: AZD3480
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab/Vibostolimab Coformulation (MK-7684A) or Pembrolizumab/Vibostolimab Coformulation Plus Docetaxel Versus Docetaxel for Metastatic Non Small Cell Lung Cancer (NSCLC) With Progressive Disease After Platinum Doublet Chemotherapy and Immunotherapy (MK-7684A-002, KEYVIBE-002)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Non Small Cell Lung Cancer
Interventions: BIOLOGICAL: Pembrolizumab/Vibostolimab coformuation|DRUG: Docetaxel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ACCEPTABILITY AND WRITING FREQUENCY OF ADVANCED DIRECTIVES IN ONCO-DERMATOLOGY PATIENTS
Status: UNKNOWN
Conditions: Advance Directives|Oncology|Skin Cancer|Melanoma|Skin Lymphoma|Skin Squamous Cell Carcinoma|Metastatic Basal Cell Carcinoma
Interventions: OTHER: no intervention, only complete a survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Emapalumab for Pediatric Aplastic Anemia
Status: RECRUITING
Conditions: Aplastic Anemia|Cytopenia|Hypocellular Marrow
Interventions: BIOLOGICAL: Emapalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Levonorgestrel-intrauterine System (LNG-IUS) Versus Depot Medroxyprogesterone Acetate (DMPA) in Treatment of Pelvic Pain in Clinically Diagnosed Endometriotic Patients
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: LNG-IUS|DRUG: DMPA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety Study for GSK573719/GW642444 in Japanese
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK573719/GW642444 Inhalation Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition
Status: ACTIVE_NOT_RECRUITING
Conditions: Cannabis|Alcohol Effect|Driving Under the Influence of Alcohol and Other Drugs
Interventions: DRUG: Active delta-9-THC|DRUG: Placebo|DRUG: Active Ethanol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Predicting Factors for the Outcome of Surgical Treatment for Patellar Instability
Status: UNKNOWN
Conditions: Patellar Dislocation
Interventions: PROCEDURE: Reconstruction of MPFL with or without tibial tuberositas osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulation of Fear Extinction Processes Using Transcranial Electrical Stimulation
Status: COMPLETED
Conditions: Stress Related Disorder|Anxiety
Interventions: DEVICE: Sham stimulation (1.5 milliampere,30 seconds)|DEVICE: DC stimulation (1.5 milliampere, 20 minutes)|DEVICE: AC stimulation (1.5 milliampere,1.5 Hertz frequency)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of "Vitamin N" Nature Immersion Therapy on Stress Levels in Health Care Workers in the City of Bogotá
Status: NOT_YET_RECRUITING
Conditions: Cortisol Excess|Stress, Psychological|Anxiety|Epigenetic Disorder|Natural Killer Cell Cytokine Production|Environmental Exposure
Interventions: OTHER: Immersion therapy in nature - Vitamin N
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Carboplatin, Pemetrexed, and Panitumumab in Patients With Advanced Non-Squamous K-ras Wild Type NSCLC
Status: COMPLETED
Conditions: Non-Small-Cell Lung Cancer
Interventions: DRUG: Carboplatin|DRUG: Pemetrexed|DRUG: Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Survivorship Care Planning for Patients With Localized Prostate Cancer Using A Couple-focused Web-based Tailored Symptom Self-management Program
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: OTHER: Survivorship Care Plan|OTHER: Enhanced Survivorship Care Plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating Safety and Efficacy of Bazedoxifene/Conjugated Estrogens Combinations in Postmenopausal Women
Status: COMPLETED
Conditions: Endometrial Hyperplasia|Osteoporosis
Interventions: DRUG: Bazedoxifene/Conjugate Estrogens (CE)|DRUG: Raloxifene|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing CRT With ECGI
Status: TERMINATED
Conditions: Heart Failure, Systolic|Left Bundle-Branch Block
Interventions: OTHER: ECGI-optimized VV-offset|OTHER: Zero VV-offset
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Temisartan/Amlodipine & Rosuvastatin in Subjects With Hypertension and Hyperlipidemia
Status: COMPLETED
Conditions: Hypertension|Hyperlipidemia
Interventions: DRUG: Temisartan+Amlodipine+Rosuvastatin (Combination drug)|DRUG: Temisartan+Amlodipine|DRUG: Temisartan+Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Liposomal Bupivacaine Administered Following Placement of a Transobturator Suburethral Sling
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Placebo|DRUG: Liposomal bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cabazitaxel in Patients With Urothelial Carcinoma Who Have Disease Progression Following Platinum-Based Chemotherapy
Status: COMPLETED
Conditions: Urothelial Carcinoma
Interventions: DRUG: Cabazitaxel|DRUG: Neulasta|PROCEDURE: CT Scan|BIOLOGICAL: Blood Draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Focus On Stiffness Reduction, Endothelial Function and Autonomic Nervous System
Status: COMPLETED
Conditions: Arterial Stiffness|Endothelial Function|Autonomic Nervous System|Acute Coronary Syndrome|Arterial Hypertension
Interventions: OTHER: comprehensive cardiac rehabilitation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Dexmedetomidine and Bupivacaine for Paravertebral Block
Status: COMPLETED
Conditions: Fracture of Proximal Femur
Interventions: DRUG: Bupivacaine|DRUG: Mixture of bupivacaine and dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Comparison Of Ultrasound-Guided Continuous Erector Spinae Plane Block Versus Thoracic Epidural Analgesia
Status: RECRUITING
Conditions: Post Operative Pain
Interventions: OTHER: THORACIC EPIDURAL BLOCK|OTHER: ERECTOER SPINE BLOCK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Engage Psychosocial Intervention for Cancer Symptoms
Status: NOT_YET_RECRUITING
Conditions: Advanced Breast Cancer|Advanced Prostate Cancer|Advanced Lung Cancer|Advanced Colorectal Carcinoma|Advanced Colorectal Adenocarcinoma
Interventions: BEHAVIORAL: ENGAGE|BEHAVIORAL: Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PRe-Exposure Prophylaxis Acceptability & Readiness Assessments for Toronto gaY, Bisexual and Other Men Who Have Sex With Men-5
Status: COMPLETED
Conditions: HIV|Human Immunodeficiency Virus
Interventions: DRUG: Tenofovir/emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Abscopal Effect for Metastatic Colorectal Cancer
Status: WITHDRAWN
Conditions: Colorectal Cancer|Metastatic Colorectal Cancer|Thymalfasin
Interventions: RADIATION: Radiation therapy|DRUG: Thymalfasin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Rotator Cuff Repair of Full Thickness Tears With and Without Arthroscopic Acromioplasty
Status: COMPLETED
Conditions: Rotator Cuff Tear|Shoulder Impingement Syndrome
Interventions: PROCEDURE: Acromioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Crossover Trial of AD036 in Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: AD036|DRUG: Atomoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DPP-4 Inhibitors and Acute Myocardial Infarction:Effects on Platelet Function
Status: COMPLETED
Conditions: Platelet Aggregation During Acute Myocardial Infarction
Interventions: DRUG: sitagliptin OR saxagliptin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: By Youth, For Youth: Digital Supported Peer Navigation for Addressing Child Mental Health Inequities
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Depression|Mental Health Issue
Interventions: BEHAVIORAL: Navigator Plus App Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase II Study of Interleukin-21 (rIL-21) vs Dacarbazine (DTIC) in Patients With Metastatic or Recurrent Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: rIL-21|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of 6% Hydroxyethyl Starch 130/0.4 With 5% Albumin as Priming Solution for Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Mitral Valvular Heart Disease
Interventions: DRUG: 6% hydroxyethyl starch 130/0.4 and 5% albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Sorafenib and Gemcitabine in Advanced Hepatocellular Carcinoma (HCC)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: sorafenib|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Zileuton (Zyflo) in Combination With Imatinib Mesylate (Gleevec) in CML.
Status: TERMINATED
Conditions: Chronic Myelogenous Leukemia
Interventions: DRUG: Zileuton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sofosbuvir + Ribavirin for 12 Weeks in Subjects With Chronic Genotype 2 or 3 Hepatitis C Infection Who Are Interferon Intolerant, Interferon Ineligible or Unwilling to Take Interferon
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: SOF|DRUG: RBV|DRUG: Placebo to match SOF|DRUG: Placebo to match RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Cement-bone Incorporation and Adjacent Segment Degeneration Following Cement Augmentation; an MRI-PET Follow-up
Status: UNKNOWN
Conditions: Vertebral Fracture|Cement Augmentation
Interventions: DIAGNOSTIC_TEST: PET MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PET Imaging of 68Ga-NOTA-H006 in Malignancy
Status: NOT_YET_RECRUITING
Conditions: Tumor, Solid
Interventions: DRUG: 68Ga-NOTA-H006 is injected intravenously with a dose of 1.8 MBq[0.05MCi]/kg.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetics Trial of Isosorbide Mononitrate 0.5% Gel for Intra Anal Application in Healthy Subjects
Status: WITHDRAWN
Conditions: Pharmacokinetics|Healthy Subjects
Interventions: DRUG: Isosorbide mononitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dose Escalation and Safety Study of 188Re-PTI-6D2 in Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: DRUG: PTI-6D2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bismuth Quadruple Therapy in Helicobacter Pylori Rescue Therapy of Different Tetracycline Doses and Frequencies.
Status: RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Tetracycline 500mg tid|DRUG: Tetracycline 500mg qid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Training of Falling Techniques on Landing Mechanics
Status: NOT_YET_RECRUITING
Conditions: Sports Injury|Orthopedic Disorder|Knee Injuries|Anterior Cruciate Ligament Injuries
Interventions: OTHER: Falling Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Wearing a Compression Sock During Running on Muscle Soreness in Distance Runners.
Status: ENROLLING_BY_INVITATION
Conditions: Muscle Soreness|Perceived Recovery|Perceived Exertion|Affective Response|Heart Rate
Interventions: OTHER: Compression socks|OTHER: Placebo socks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Virtual Reality Software on Nurses' Clinical Practice, Problem Solving and Clinical Decision Making Skills and Anxiety in the Care Management of Intensive Care Patients.
Status: ACTIVE_NOT_RECRUITING
Conditions: Nurse's Role|Anxiety|Nursing Caries
Interventions: OTHER: Virtual Reality Software
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparing Efficacity of Analgesia Between Ultrasound-guided Nerve Block and Local Infiltration After Wrist Fracture Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Wrist Fracture
Interventions: PROCEDURE: Local infiltration anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Megestrol Acetate Plus LNG-IUS in Young Women With Endometrial Atypical Hyperplasia
Status: COMPLETED
Conditions: Atypical Endometrial Hyperplasia
Interventions: DRUG: Megestrol Acetate|DEVICE: Levonorgestrel-releasing Intrauterine System(LNG-IUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Ruxolitinib Versus Best Available Therapy Trial in Patients With High Risk ET in Second Line
Status: TERMINATED
Conditions: Essential Thrombocythemia
Interventions: DRUG: Anagrelide|DRUG: Ruxolitinib (JAKAVI®)|DRUG: IFNα/ PegIFNα
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Potential Role of the Gut Microbiome in Modulating Physical Abilities in Humans
Status: UNKNOWN
Conditions: Physical Abilities|FMT
Interventions: DRUG: Antibiotics|OTHER: Fecal Microbiota Transplantation|OTHER: Cellules Pills|OTHER: Agarose Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cinacalcet in Paediatric Secondary Hyperparathyroidism (SHPT) Due to Chronic Kidney Disease (CKD)
Status: UNKNOWN
Conditions: Secondary Hyperparathyroidism
Interventions: DRUG: Cinacalcet HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tenofovir Antiviral Therapy Following Transarterial Chemoembolization for HBV Related Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Chronic Hepatitis B|Hepatocellular Carcinoma
Interventions: DRUG: Tenofovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Gamma Tocopherol Enriched Supplementation on Response to Inhaled O3 Exposure
Status: COMPLETED
Conditions: Allergic Asthma
Interventions: DRUG: gamma tocopherol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nutrition Goes to School: a School-based Nutrition Intervention to Promote Healthy Eating Behaviour Among Adolescents
Status: RECRUITING
Conditions: Obesity, Adolescent
Interventions: BEHAVIORAL: Nutrition Goes To School (NGTS) Program Intervention Package|BEHAVIORAL: Nutrition Education Capacity Building for Teachers and Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Peri-Operative Docetaxel Plus Laparoscopic Radical Prostatectomy in Prostate Cancer Patients
Status: SUSPENDED
Conditions: Prostate Cancer
Interventions: DRUG: docetaxel|PROCEDURE: laparoscopic radical prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ADX48621 for the Treatment of Levodopa Induced Dyskinesia in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: ADX48621|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Placenta Accreta Spectrum Outcome After Uterine Conservation
Status: RECRUITING
Conditions: Placenta Accreta Spectrum
Interventions: PROCEDURE: closure of the uterine wall defect|DIAGNOSTIC_TEST: ultrasound|DIAGNOSTIC_TEST: outpatient hysteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Trial of Video Education in Nursing Homes
Status: COMPLETED
Conditions: Alzheimer Disease|Dementia|Heart Failure|Pulmonary Disease, Chronic Obstructive
Interventions: BEHAVIORAL: ACP Video Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Lymphocyte Support to SBRT in Patients With Oligo-metastatic Solid Cancer
Status: RECRUITING
Conditions: Oligometastatic Disease|Solid Tumor, Adult
Interventions: DRUG: all-trans retinoic acid|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suicide Intervention for Alaska Native Youth
Status: RECRUITING
Conditions: Alaska Native Youth Aged 14 - 24|Suicide, Attempted|Suicidal Ideation|Alcohol Intoxication
Interventions: BEHAVIORAL: Tools for Life|BEHAVIORAL: Tools for Life + MISN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Providing an Optimized and emPowered Pregnancy for You (PᵌOPPY) Feasibility Study
Status: COMPLETED
Conditions: Pregnancy|Infants|Disparities
Interventions: BEHAVIORAL: Digital Health intervention|BEHAVIORAL: Community Health Worker|BEHAVIORAL: Digital Health Intervention plus Community Health Worker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: The Biodistribution and Potential Diagnostic Ability of 18F FACBC in Patients With Head and Neck, Breast, and Prostate Cancer
Status: COMPLETED
Conditions: Breast Cancer|Head and Neck Cancer|Prostate Cancer
Interventions: PROCEDURE: novel PET tracer FACBC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cyclophosphamide for Acute Exacerbation of Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Cyclophosphamide|DRUG: Placebo|DRUG: Corticosteroid (prednisolone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EUS-FNA for Retropharyngeal Lymph Node (RPLN) in Recurrent Nasopharyngeal Carcinoma (NPC) Patients
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: PROCEDURE: EUS-FNA for RPLN in NPC patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The EVARREST® Fibrin Sealant Patch Liver Study
Status: COMPLETED
Conditions: Hemorrhage
Interventions: BIOLOGICAL: EVARREST® Fibrin Sealant Patch|OTHER: Standard of Care (SoC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Continuous Glucose Monitor Use in Underserved Primary Care Patients
Status: ENROLLING_BY_INVITATION
Conditions: Type 2 Diabetes
Interventions: DEVICE: Continuous glucose monitor|DEVICE: Traditional glucometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroregulatory Effect and Mechanism of tDCS on Medial Prefrontal Cortex in ASD
Status: COMPLETED
Conditions: ASD
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid to Reduce Blood Loss in Spine Trauma Surgery
Status: RECRUITING
Conditions: Spinal Injuries|Spinal Deformity
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Losartan Versus Hydrochlorothiazide in Reversing Remodeling of Small Arteries in Pre-Hypertensive Pre-Diabetic Subjects
Status: TERMINATED
Conditions: Pre-hypertension|Pre-diabetes
Interventions: DRUG: losartan, hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Eltrombopag on the Expression of Platelet Collagen Receptor GPVI in Pediatric ITP.
Status: COMPLETED
Conditions: Idiopathic Thrombocytopenic Purpura
Interventions: DRUG: Eltrombopag|DRUG: conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Nutritional Supplementation (Product 4808) on Acute Skeletal Muscle Protein Synthesis in Cancer Patients
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: Standardized Meals for Diet Stabilization|DIETARY_SUPPLEMENT: Forticare|DIETARY_SUPPLEMENT: Product 4808
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Non-Opiate Treatment After Prenatal Opiate Exposure to Prevent Postnatal Injury to the Young Brain
Status: ACTIVE_NOT_RECRUITING
Conditions: Neonatal Abstinence Syndrome
Interventions: DRUG: Clonidine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Assess the Efficacy and Safety of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-383)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Ezetimibe 10 mg|DRUG: Atorvastatin 10 mg|DRUG: Placebo for Ezetimibe 10 mg tablet|DRUG: Placebo for Atorvastatin 10 mg capsule|BEHAVIORAL: Diet control/Daily Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of GLP-1 Receptor Agonists on Trabecular Bone Score
Status: TERMINATED
Conditions: Osteoporosis, Postmenopausal|Diabetes Mellitus, Type 2
Interventions: DRUG: GLP-1 receptor agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emergency Echocardiography in Sepsis
Status: RECRUITING
Conditions: Sepsis|Echocardiography|Organ Dysfunction Syndrome Sepsis|Emergencies
Interventions: PROCEDURE: early transthoracic echocardiography|PROCEDURE: standards of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study With the Antibody, cG250, and Isotope, 124-Iodine, to Diagnose Patients With Renal Masses.
Status: COMPLETED
Conditions: Cancer of Kidney|Kidney Cancer|Renal Cancer|Neoplasms, Kidney|Renal Neoplasms|Renal Cell Carcinoma (RCC)|Clear Cell Renal Cell Carcinoma
Interventions: DRUG: 124-Iodine-cG250 (124I-cG250)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Body Awareness and Mental Fatigue in Neck Pain
Status: NOT_YET_RECRUITING
Conditions: Neck Pain|Mental Fatigue|Mindfulness|Awareness
Interventions: OTHER: Mental Fatigue:|OTHER: Body Awareness:|OTHER: Neck Disability Level|OTHER: Quality Of Life|OTHER: Pain Assessment:|OTHER: Physical Condition:|OTHER: Anxiety and Depression:
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Registry of Patients Undergoing Cellvizio Endomicroscopy and Endoscopic Retrograde Cholangiopancreatography(ERCP) Imaging Procedures for Diagnosing Pancreatic and Bile Duct Cancers
Status: COMPLETED
Conditions: Pancreatic Cancer|Bile Duct Cancer
Interventions: DEVICE: Probe-based confocal laser endomicroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fistulodesis Pilot Study for Closure of Perianal Fistulae
Status: UNKNOWN
Conditions: Perianal Fistula|Crohn Disease
Interventions: PROCEDURE: Fistulodesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Radiation Therapy in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: capecitabine|DRUG: carboplatin|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Cardiac Dysfunction During Breast Cancer Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer Female|Heart Failure
Interventions: DRUG: Sacubitril/valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Platelet Function After Administration of Aspirin Versus Lysine Acetylsalicylate in STEMI Patients
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Lysine Acetilsalicilate|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Combined With rTMS for the Treatment of Depression : a Randomized Clinical Trial.
Status: UNKNOWN
Conditions: the Treatment of Depression
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS - ) MagPro®|DEVICE: virtual reality for displaying interactive virtual environments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Asleep Fiberoptic vs Direct Laryngoscopy Effect on Hemodynamic Stability Using Opioid Free Anesthesia Induction
Status: NOT_YET_RECRUITING
Conditions: Analgesics, Opioid|Anesthesia, General|Heart Rate|Blood Pressure
Interventions: DEVICE: direct conventional laryngoscopy|DEVICE: fiberoptic guided intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Amount of Drug Levels in Blood and Safety of AZD5718 Formulations in Healthy Volunteers
Status: COMPLETED
Conditions: Coronary Artery Disease (CAD)
Interventions: DRUG: AZD5718 tablet, Formulation A|DRUG: AZD5718 tablet, Formulation B|DRUG: AZD5718 tablet, Formulation C|DRUG: AZD5718 tablet, Formulation D|DRUG: AZD5718 film-coated tablet, Reference treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Fecal Transplant in Cirrhosis
Status: COMPLETED
Conditions: Hepatic Encephalopathy|Cirrhosis, Liver
Interventions: DRUG: FMT|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: IMAging With Opto-acoustics to downgradE BI-RADS claSsificaTion Relative tO Other Diagnostic Methodologies (MAESTRO)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: Imagio IUS|DEVICE: Imagio OA/US
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assess the Safety and Adhesive Performance of the VIPER System When Compared to Esteem™
Status: COMPLETED
Conditions: Ostomy
Interventions: DEVICE: VIPER|DEVICE: Esteem™ Cut to Fit One Piece Closed End Pouch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TACE Plus Recombinant Human Adenovirus for Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Recombinant Human Adenovirus Type 5 Injection|PROCEDURE: Transartery Chemoembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroprotective Effect of Vitamin B12 and Vitamin B6 Against Vincristine Induced Peripheral Neuropathy
Status: COMPLETED
Conditions: Vincristine Induced Peripheral Neuropathy (VIPN)
Interventions: DRUG: Injection Mecobalamin,|DRUG: Tablet Pyridoxine hydrochloride|DRUG: Intravenous normal saline 1 ml|DRUG: Placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Controlled Trial to Promote Physician-Patient Discussion of Prostate Cancer Screening
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Educational handout about prostate cancer screening|PROCEDURE: Simple cue for patient to talk to doctor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: ECT
Clinical trial: The Effects of Connective Tissue Manipulation and Abdominal Massage in Patients With Chronic Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: OTHER: lifestyle advice|OTHER: connective tissue manipulation|OTHER: abdominal massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Micro Vascular Dysfunction in Acute Myocardial Infarction by Ticagrelor
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: DRUG: Ticagrelor|DRUG: Prasugrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study IV QUZYTTIR™ (Cetirizine Hydrochloride Injection) vs V Diphenhydramine
Status: COMPLETED
Conditions: Oncology Patients Receiving Chemotherapy
Interventions: DRUG: Cetirizine HCl 10 mg/mL|DRUG: Diphenhydramine 50 mg/mL|DRUG: anti-CD20 such as Rituximab or Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Additional Propacetamol Infusion on Post Procedural Outcome and Opioid Consumption During Catheter Ablation of Atrial Fibrillation.
Status: COMPLETED
Conditions: Arrhythmia
Interventions: DRUG: Propacetamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy and Denileukin Diftitox in Treating Patients With Newly Diagnosed T-Cell Non-Hodgkin Lymphoma
Status: WITHDRAWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: denileukin diftitox|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: doxorubicin hydrochloride|DRUG: leucovorin calcium|DRUG: methotrexate|DRUG: prednisone|DRUG: vincristine sulfate|GENETIC: protein expression analysis|OTHER: flow cytometry|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Cytoxan, Epirubicin and Capecitabine in Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Stage I Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer
Interventions: DRUG: Cyclophosphamide|DRUG: Epirubicin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of JR-441 in Patients With Mucopolysaccharidosis Type IIIA
Status: RECRUITING
Conditions: Mucopolysaccharidosis III-A
Interventions: DRUG: JR-441|DRUG: JR-441
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Biobehavioral Intervention to Reduce Adverse Outcomes in Young Adult Testicular Cancer Survivors
Status: RECRUITING
Conditions: Testicular Cancer
Interventions: BEHAVIORAL: Goal-Focused Emotion-Regulation Therapy (GET)|BEHAVIORAL: Individual Supportive Listening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: miR-142-3p as Potential Biomarker of Synaptopathy in MS
Status: RECRUITING
Conditions: Multiple Sclerosis|Spasticity
Interventions: PROCEDURE: lumbar puncture and blood withdrawal|PROCEDURE: Intermittent theta burst stimulation (iTBS) therapeutic protocol for spasticity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SLV308 for Treatment of Patients With Parkinson's Disease Experiencing Motor Fluctuations
Status: COMPLETED
Conditions: Advanced Stage Parkinson's Disease
Interventions: DRUG: Levodopa (Pardoprunox)|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liposomal Bupivacaine (Exparel) in Sarcomas
Status: TERMINATED
Conditions: Soft Tissue Sarcoma|Soft Tissue Tumor|Soft Tissue Tumor and/or Sarcoma
Interventions: DRUG: Liposomal Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of the App Bone@BC Version 4.0 Under the Follow-up for Patients With Early Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Early-stage Breast Cancer
Interventions: DEVICE: Bone@BC app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Dose-finding Study of a Combination of Imatinib and BKM120 in the Treatment of 3rd Line GIST Patients
Status: COMPLETED
Conditions: 3rd Line GIST
Interventions: DRUG: STI571|DRUG: BKM120
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dalpiciclib Combination With Fulvestrant and Compound Gossyfol Acetate Tablets in Women With CDK4/6 Inhibitor-refractory HR-positive HER-2 Negtive Metastatic Breast Cancer: a Phase 2 Clinical Trial.
Status: RECRUITING
Conditions: Advanced HR-positive and HER2-negative Breast Cancer; CDK4/6 Inhibitor Treatment Failed
Interventions: DRUG: dalpiciclib; fluvestrant; compound gossypol acetate tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Positional Therapy on Symptoms of Gastroesophageal Reflux Disease: A Prospective Pilot Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastro Esophageal Reflux
Interventions: DEVICE: LEFT Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ED90 for Hyperbaric Bupivacaine in Super Obese Parturients
Status: COMPLETED
Conditions: Obesity, Morbid|Spinal Anesthesia|Cesarean Delivery
Interventions: DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Melissa Officinalis L. Supplementation for Emotional Health and Sleep Disturbance
Status: COMPLETED
Conditions: Depression|Anxiety|Stress|Insomnia
Interventions: DIETARY_SUPPLEMENT: Lemon Balm Supplement|DIETARY_SUPPLEMENT: Matched Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Muscular Relaxation and Breathing Technique on Blood Pressure in Pregnancy
Status: TERMINATED
Conditions: Blood Pressure in Pregnancy
Interventions: BEHAVIORAL: muscular relaxation|BEHAVIORAL: breath control|OTHER: control (routine care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of NeuroStar® Transcranial Magnetic Stimulation (TMS) Therapy in Depressed Adolescents
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DEVICE: Active NeuroStar® Transcranial Magnetic Stimulation (TMS)|DEVICE: Sham NeuroStar® Transcranial Magnetic Stimulation (TMS)|DEVICE: Open Label Active NeuroStar® TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab Combined With Apatinib in Patients With First-line Platinum-resistant Recurrent/Metastatic Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Camrelizumab|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining Choice Architecture for Genetic Testing Decisions
Status: COMPLETED
Conditions: Decision Making
Interventions: BEHAVIORAL: choice decision frame|BEHAVIORAL: opt-in decision frame|BEHAVIORAL: opt-out decision frame|BEHAVIORAL: enhanced choice (context) decision frame|BEHAVIORAL: enhanced choice (norms) decision frame|BEHAVIORAL: enhanced choice (affect) decision frame
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of an Adapted Physical Activity With an Interactive Gaming Platform on Fear of Falling and Risk of Falling
Status: UNKNOWN
Conditions: Falls (Accidents) in Old Age
Interventions: OTHER: Medimoov|OTHER: Standard psychomotor therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sunitinib in Treating Patients With Progressive Metastatic Transitional Cell Cancer of the Urothelium
Status: COMPLETED
Conditions: Bladder Cancer|Transitional Cell Cancer of the Renal Pelvis and Ureter|Urethral Cancer
Interventions: DRUG: sunitinib malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tirapazamine Plus Cyclophosphamide in Treating Children With Refractory Solid Tumors
Status: COMPLETED
Conditions: Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: tirapazamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT