pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Prophylaxis of COVID-19 Disease With Ivermectin in COVID-19 Contact Persons [German: Prophylaxe Der COVID-19-Erkrankung Mit Ivermectin Bei COVID-19 Kontaktpersonen]
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: Ivermectin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Performance of the Baska MaskⓇ, the I-GelⓇ and the Self-Pressurized Air-QⓇ i
Status: UNKNOWN
Conditions: The Baska Mask
Interventions: DEVICE: airway divice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Repurposing Empagliflozin and Dapagliflozin for Paediatric Heart Failure: Translational Approach and Dose Rationale
Status: NOT_YET_RECRUITING
Conditions: Heart Failure
Interventions: DRUG: Dapagliflozin tablet|DRUG: Empagliflozin Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate D2 Receptor Occupancy Following Single Intravenous Administration of ATI-9242
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: ATI-9242|RADIATION: [18F]Fallypride Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
Status: RECRUITING
Conditions: COPD (Chronic Obstructive Pulmonary Disease)
Interventions: DRUG: BGF MDI 320/14.4/9.6 μg|DRUG: GFF MDI 14.4/9.6 μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PHP in Combination With IPI1/NIVO3 Compared to IPI3/NIVO1 Only in Patients With Uveal Melanoma Liver Metastases
Status: NOT_YET_RECRUITING
Conditions: Uveal Melanoma|Liver Metastases
Interventions: DEVICE: PHP|DRUG: IPI1/NIVO3|DRUG: IPI3/NIVO1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety, Tolerability and Pharmacokinetics of BG00010 (Neublastin) Administered to Sciatica Participants
Status: COMPLETED
Conditions: Sciatica
Interventions: DRUG: BG00010 (Neublastin)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Madalena Association in the Treatment of Type II Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: MADALENA ASSOCIATION|DRUG: METFORMIN|DRUG: EMPAGLIFLOZIN + LINAGLIPTIN|OTHER: MADALENA ASSOCIATION PLACEBO|OTHER: METFORMIN PLACEBO|OTHER: EMPAGLIFLOZIN + LINAGLIPTIN PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Joint Attention-Based Occupational Therapy Intervention in Pre-Schoolers With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Social Communication|Behavior Problem|Visual Perceptual Weakness
Interventions: BEHAVIORAL: Occupational Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enhanced Gait and Balance Training
Status: COMPLETED
Conditions: Aging|Accidental Falls
Interventions: DEVICE: Cranial Nerve Non-Invasive Neuromodulation|BEHAVIORAL: Sham Cranial Nerve Non-Invasive Neuromodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Dapagliflozin on Secondary Mitral Regurgitation
Status: RECRUITING
Conditions: Dilated Cardiomyopathy
Interventions: DRUG: Dapagliflozin Farxiga®|DRUG: Ramipril Tritace®, Carvedilol Carvid®,and Spironolactone Aldactone®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nociception Level Index as Monitorization of Pain at the Intensive Care
Status: COMPLETED
Conditions: Intensive Care, Surgical|Anesthesia, General
Interventions: DEVICE: nociception level index monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Relationship of Preoperative Fasting With Tricuspid Annular Plane Systolic Excursion
Status: ENROLLING_BY_INVITATION
Conditions: The Relationship Between TAPSE Value and Volume
Interventions: DIAGNOSTIC_TEST: Tricuspid Annular Plane Systolic Excursion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stem Cell Therapy for Patients With Focal Segmental Glomerulosclerosis
Status: COMPLETED
Conditions: Focal Segmental Glomerulosclerosis|Chronic Kidney Diseases
Interventions: OTHER: Bone marrow stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of SECOX Versus Sorafenib as First-Line Treatment in Patients With Advanced Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular|Secondary
Interventions: DRUG: Sorafenib|DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of BIBR 953 ZW in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBR 1048 low1|DRUG: BIBR 1048 low2|DRUG: BIBR 1048 medium|DRUG: BIBR 1048 high|DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Release Kinetics in PRF Versus GEM21S With and Without Bone Substitutes: An In Vitro Analysis
Status: ACTIVE_NOT_RECRUITING
Conditions: Bone Loss
Interventions: BIOLOGICAL: Amount of PDGF-BB in PRF preparation vs. GEM21|BIOLOGICAL: Amount of PDGF-BB available in PRF + bone substitutes vs. rhPDGF-BB+ bone substitutes following preparation|BIOLOGICAL: Release kinetics of PDGF-BB in PRF + bone substitutes vs. rhPDGF-BB + bone substitutes|BIOLOGICAL: Release kinetics of PDGF-BB in rhPDGF-BB + PRF + bone substitutes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Total Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome
Status: TERMINATED
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Childhood Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Myeloid Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Refractory Anemia With Excess Blasts|Refractory Anemia With Excess Blasts in Transformation|Refractory Anemia With Ringed Sideroblasts|Refractory Cytopenia With Multilineage Dysplasia|Secondary Acute Myeloid Leukemia|Secondary Myelodysplastic Syndromes
Interventions: RADIATION: iodine I 131 monoclonal antibody BC8|DRUG: fludarabine phosphate|RADIATION: total-body irradiation|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation|DRUG: cyclosporine|DRUG: mycophenolate mofetil|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerability and Modulatory Action of the Butyrate Releaser N-(1-carbamoyl-2-phenyl-ethyl) Butyramide
Status: COMPLETED
Conditions: Safety Issues
Interventions: DIETARY_SUPPLEMENT: FBA|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of Ozurdex® Treatment Practice in Patients With Macular Oedema Due to Retinal Vein Occlusion
Status: COMPLETED
Conditions: Macular Edema|Retinal Vein Occlusion
Interventions: DRUG: dexamethasone intravitreal implant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Twelve Month Study Comparing Paliperidone Palmitate and Select Oral Antipsychotics in Adults With Schizophrenia Who Have Been Recently Discharged From an Inpatient Psychiatric Hospital
Status: WITHDRAWN
Conditions: Schizophrenia
Interventions: DRUG: paliperidone palmitate|DRUG: risperidone|DRUG: olanzapine|DRUG: aripiprazole|DRUG: haloperidole|DRUG: quetiapine|DRUG: perphenazine|DRUG: paliperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of GABA Agonists in Reducing the Reinforcing Effects of Cocaine
Status: COMPLETED
Conditions: Cocaine-Related Disorders
Interventions: DRUG: GABA Agonists
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Misoprostol and PGE2 Gel for Induction of Labour in Women With Premature Rupture of Membranes at Term
Status: COMPLETED
Conditions: Premature Rupture of Membranes at Term
Interventions: DRUG: Misoprostol|DRUG: PGE2 gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Antibody for Methamphetamine Outpatient Therapy
Status: COMPLETED
Conditions: Methamphetamine-dependence|Methamphetamine Abuse
Interventions: DRUG: Placebo|DRUG: IXT-m200
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing Circulation Around Surgical Incisions at the Time of Laparotomy Closure
Status: COMPLETED
Conditions: Laparotomy
Interventions: PROCEDURE: Laparotomy|OTHER: ICG|OTHER: Spectrum NIR imaging system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biological, Genetic, and Lifestyle Risk Factors for Developing Colorectal Adenomas or Polyps in Participants Undergoing Colonoscopy
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer|Precancerous Condition
Interventions: OTHER: biologic sample preservation procedure|OTHER: cytology specimen collection procedure|OTHER: medical chart review|OTHER: questionnaire administration|OTHER: survey administration|PROCEDURE: biopsy|PROCEDURE: evaluation of cancer risk factors|PROCEDURE: screening colonoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase III Randomized, Double-blind, Parallel-group Study to Evaluate the Efficacy and Safety of Acarmet (Metformin HCl 500 mg Plus Acarbose 50 mg Tablets) Versus Acarbose Alone in Subjects With Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: The Objectives of the Study is to Evaluate the Efficacy and Safety of Acarmet (Metformin HCl 500 mg|Plus Acarbose 50 mg Tablets) Thrice Daily Versus Acarbose 50 mg Thrice Daily Over 16 Weeks in|Subjects With Type 2 Diabetes Mellitus.
Interventions: DRUG: Acarbose|DRUG: Metformin/Acarbose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development of Distress Management Algorithms Using Mobile Device Based Health Logs in Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Cancer|Quality of Life
Interventions: DEVICE: Wearable device (Fitbit Charge HR® or Fitbit Alta ®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Exercise and Cognitive Retraining to Improve Cognition in Heart Failure.
Status: COMPLETED
Conditions: Heart Failure
Interventions: BEHAVIORAL: Exercise and Cognitive retraining|BEHAVIORAL: Exercise Only|BEHAVIORAL: Stretching and Flexibility
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Changes in Quadriceps Function Following Local or Distant Interventions in Individuals With Patellofemoral Pain
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome|Chondromalacia Patellae|Anterior Knee Pain Syndrome
Interventions: OTHER: Lumbopelvic Manipulation|OTHER: TENS- Spine|OTHER: TENS- Knee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effects of Itraconazole, Rifampicin, and Omeprazole on Pharmacokinetics of Adavosertib
Status: TERMINATED
Conditions: Advanced Solid Tumours
Interventions: DRUG: Adavosertib|DRUG: Itraconazole|DRUG: Rifampicin|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Repeatability of 68-GaNOTA-Anti-HER2 VHH1 PET/CT in Breast Carcinoma Patients
Status: RECRUITING
Conditions: Metastatic Breast Carcinoma|Locally Advanced Breast Cancer|Cancer of Pancreas|Solid Tumor With Intermediate or High HER2 Expression|Salivary Gland Cancer|Gastric Cancer|Endometrial Cancer|Uterine Cancer|Non Small Cell Lung Cancer|Biliary Tract Cancer|Cholangiocarcinoma|Colorectal Cancer|Urothelial Carcinoma|Prostate Cancer
Interventions: DRUG: 68GaNOTA-Anti-HER2 VHH1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Deferasirox for Treatment of Transfusional Iron Overload in Myelodysplastic Patients
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Iron Overload
Interventions: DRUG: Deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Robotic Versus Laparoscopic Ventral Hernia Repair
Status: COMPLETED
Conditions: Hernia, Ventral
Interventions: PROCEDURE: Robotic Repair|PROCEDURE: Laparoscopic Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesia With Liposomal Bupivacaine Versus Standard Bupivacaine Combined With Dexamethasone
Status: COMPLETED
Conditions: Liver Cancer
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine Hydrochloride combined with dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation of Patients With Hematological Diseases
Status: COMPLETED
Conditions: Hematologic Malignancy
Interventions: DRUG: ANTI-CD45|DRUG: CAMPATH-1H|DRUG: FK506|DRUG: Fludarabine|RADIATION: Total Body Irradiation|PROCEDURE: Stem cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incidence of Occluded Culprit Arteries and Impact of Coronary Collaterals on Outcome in Patients With NSTEMI
Status: COMPLETED
Conditions: NSTEMI
Interventions: PROCEDURE: percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Elastography of Myofascial Pain Syndrome
Status: ENROLLING_BY_INVITATION
Conditions: Myofascial Pain
Interventions: DIAGNOSTIC_TEST: Magnetic Resonance (MR) Elastography|DIAGNOSTIC_TEST: MRI structural imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study on the Effect of Kidney Disease on a Diabetes Medication (0431-008)
Status: COMPLETED
Conditions: Renal Insufficiency|Hemodialysis
Interventions: DRUG: MK0431, sitagliptin phosphate / Duration of Treatment : 1 Days
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-arterial Chemotherapy for Spinal Metastases
Status: COMPLETED
Conditions: Spinal Diseases|Spinal Metastases|Spinal Tumors
Interventions: DRUG: Melphalan (intra-arterial infusion)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TRICuspid Intervention in Heart Failure Trial
Status: RECRUITING
Conditions: Heart Failure Attributable to Severe Tricuspid Regurgitation
Interventions: DEVICE: Transcatheter tricuspid valve treatment (TTVT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Investigating the Safety and Efficacy of Blinatumomab in Combination With Pembrolizumab in Adults With Relapsed or Refractory Diffuse Large B Cell Lymphoma (DLBCL)
Status: COMPLETED
Conditions: Relapsed or Refractory Diffuse Large B Cell Lymphoma (DLBCL)
Interventions: DRUG: Blinatumomab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Torrent Pharmaceuticals Ltd's Pioglitazone Hydrochloride Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Torrent's Pioglitazone Hydrochloride Tablets 45 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Effect of Omega 3 Fatty Acids on the Vascular Calcification Biomarkers Fetuin A and Osteoprotegerin in Patients With CRF
Status: COMPLETED
Conditions: Chronic Renal Failure
Interventions: DIETARY_SUPPLEMENT: Omega 3 fatty acids (fish oil) 1000 mg/day oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase III Clinical Study in Patients With Mild to Severe Scalp Psoriasis
Status: COMPLETED
Conditions: Scalp Psoriasis
Interventions: DRUG: DSXS topical|DRUG: Vehicle topical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Tolerance of Traces in Peanut/Tree Nut Allergic Children.
Status: TERMINATED
Conditions: Food Allergy|Peanut Allergy|Tree Nut Allergy
Interventions: OTHER: Oral food challenge to foods with traces
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Extracorporeal Shockwave Therapy in Long-term Functional Outcomes of Shoulder Adhesive Capsulitis
Status: COMPLETED
Conditions: Adhesive Capsulitis of Shoulder
Interventions: DEVICE: Extracorporeal Shockwave Therapy|OTHER: Conventional Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LDL-C Assessment With PCSK9 Monoclonal Antibody Inhibition Combined With Statin Therapy-2
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: BIOLOGICAL: Evolocumab|DRUG: Ezetimibe|DRUG: Placebo to Evolocumab|DRUG: Placebo to Ezetimibe|DRUG: Atorvastatin|DRUG: Rosuvastatin|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on GS300 on NAFLD
Status: UNKNOWN
Conditions: Nonalcoholic Fatty Liver|Weight Loss
Interventions: DEVICE: GS300|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation as a Treatment for Chemotherapy-Induced Peripheral Neuropathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain
Interventions: PROCEDURE: Neurofeedback Training|PROCEDURE: Electroencephalogram|BEHAVIORAL: Pain Scale|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Comparing the Efficacy and Safety Between I-CHOP and R-CHOP in Untreated CD20-Positive Diffuse Large B-cell Lymphoma Patients
Status: COMPLETED
Conditions: Diffuse, Large B-Cell, Lymphoma
Interventions: DRUG: IBI301 plus CHOP|DRUG: Rituximab plus CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of BCD-089 in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: BCD-089|BIOLOGICAL: Placebo|DRUG: Methotrexat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Wearing a Face Mask During Exercise in Youth Hockey Players During COVID-19
Status: COMPLETED
Conditions: Hypoxemia
Interventions: OTHER: Wingate exercise test and on-ice testing while wearing a face mask|OTHER: Wingate exercise test and on-ice testing while wearing a sham face mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clobazam Use in Epilepsia Partialis Continua - Pilot Study
Status: TERMINATED
Conditions: Epilepsia Partialis Continua|Kojewnikov's Epilepsy|Epilepsy
Interventions: DRUG: Clobazam|DRUG: Clonazepam|DRUG: Lorazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wisconsin Center for the Neuroscience and Psychophysiology of Meditation
Status: COMPLETED
Conditions: Mindfulness|Compassion|Meditation|Mental Health|Asthma
Interventions: BEHAVIORAL: Intensive Meditation Practice|BEHAVIORAL: Mindfulness Based Stress Reduction|BEHAVIORAL: Health Enhancement Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect and Safety of Huaier Granule Versus SOX Regimen in Gastric Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Huaier granule|DRUG: Oxaliplatin|DRUG: Tegafur, Gimeracil and Oteracil Potassium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CALLSAS Study: Effect of Continuous Positive Airway Pressure Treatment for Obstructive Apnea on Phone Usage Habits
Status: TERMINATED
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ropinirole for the Treatment of Muscle Cramps in Patients With Cirrhosis
Status: COMPLETED
Conditions: Muscle Cramp|Cirrhosis
Interventions: DRUG: Vitamin E|DRUG: Ropinirole|OTHER: Muscle cramp survey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Fixed Meals With Special Formulated Rice on Blood Glucose Levels of Healthy Volunteers.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Fibre Grain|DIETARY_SUPPLEMENT: Jasmine white rice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and Efficacy of Daratumumab and Carfilzomib-based Induction/Consolidation/Maintenance Therapy in Transplant-eligible, Ultra High-risk, Newly Diagnosed Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma|Primary Plasma Cell Leukemia|Extramedullary Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Carfilzomib|DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Cisplatin|DRUG: epirubicin|DRUG: Cyclophosphamide|DRUG: Etoposide|DRUG: Melphalan|PROCEDURE: ASCT|DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of [13C]Pyruvate as an Imaging Agent for Magnetic Resonance Imaging in Healthy Volunteers
Status: ENROLLING_BY_INVITATION
Conditions: Healthy Volunteers
Interventions: DRUG: Hyperpolarized [13C] Pyruvate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Synergistic Effects of Intra-articular Hyaluronic Acid and Platelet-rich Plasma Injections on Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis Knees Both
Interventions: COMBINATION_PRODUCT: A platelet-rich plasma (PRP)+ hyaluronic acid (HA) program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Voiding Function After Mid-Urethral Slings With and Without Local Anesthetic: Randomized Controlled Trial
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DRUG: Bupivacaine|DRUG: Saline|DRUG: Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Evaluation of MBSR and CBT for Veterans With Chronic Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain|Pain
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction|BEHAVIORAL: Cognitive Behavioral Therapy for Chronic Pain|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Pharmacokinetics, Safety and Tolerability Between Fixed-Dose Combination and Co-Administration of HGP0904, HGP0608 and HCP1306 Tablets in Healthy Male Subjects.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HCP1701|DRUG: HCP1306|DRUG: HGP0904|DRUG: HGP0608
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics Characteristics of Recombinant Oncolytic Vaccinia Virus Injection T601 as a Single Drug or in Combination With Oral Flucytosine (5-FC), in Patients With Advanced Malignant Solid Tumors
Status: UNKNOWN
Conditions: Advanced Malignant Solid Tumors
Interventions: BIOLOGICAL: T601|COMBINATION_PRODUCT: T601+5-FC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CASUS: Improved and Quality Assured Collection of First-void Urine
Status: COMPLETED
Conditions: Cervical Cancer|Cervical Intraepithelial Neoplasia|Human Papilloma Virus|HPV-Related Cervical Carcinoma|Urine
Interventions: DEVICE: Colli-Pee® (FV5000 and Small Volumes)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Analysis of the Use of N-Acetylcysteine and Vitamins in the Treatment of TBI in Geriatric Patients
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DRUG: N-Acetyl cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancement of Motor Function With Reboxetine and Transcranial Direct Current Stimulation
Status: COMPLETED
Conditions: Cerebral Stroke
Interventions: DRUG: reboxetine|DRUG: Placebo|DEVICE: tDCS verum|DEVICE: tDCS sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Osteopathic Care After Rupture of the Antero-external Cruciate Ligament of the Knee (DIDT OSTEO)
Status: RECRUITING
Conditions: Cruciate Ligament Rupture|Knee Ligament Injury|Osteopathia
Interventions: OTHER: Osteopathy|OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 10-year Follow-up of a Wide Diameter Bone Anchored Hearing Implant
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Baha® flange fixture (diameter 3.75mm; length 4mm) with 6mm abutment|DEVICE: Baha® BIA300 Implant (diameter 4.5mm; length 4mm) with 6mm abutment|PROCEDURE: Early loading
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Graft Patency Outcomes in Patients Undergoing Coronary Artery Bypass Grafting Via Minimally Invasive Coronary Surgery
Status: COMPLETED
Conditions: Arteriosclerosis of Coronary Artery Bypass Graft
Interventions: PROCEDURE: Minimally invasive coronary artery bypass graft surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protein Supplementation in Elderly With Sarcopenic Obesity Undergoing Caloric Restriction and Exercise
Status: COMPLETED
Conditions: Sarcopenic Obesity|Aging
Interventions: DIETARY_SUPPLEMENT: Protein supplement|DIETARY_SUPPLEMENT: isocaloric supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intermittent Positive-Pressure Breathing Effects in Patients With High Spinal Cord Injury
Status: TERMINATED
Conditions: Central Cord Injury Syndrome|Central Spinal Cord Syndrome
Interventions: DEVICE: intermittent positive-pressure breathing (IPPB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biorest Liposomal Alendronate With Stenting sTudy (BLAST)
Status: COMPLETED
Conditions: Coronary Artery Stenosis
Interventions: DRUG: Liposomal Alendronate|DRUG: Liposomal Alendronate|DRUG: Saline infusion (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Myocardial Dysfunction and Injury Resulting From Salter Innominate Osteotomy by Caudal Block
Status: UNKNOWN
Conditions: Cardiac Dysfunction|Myocardial Injury
Interventions: DRUG: ropivacaine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Real World Evidence of the Effectiveness of Paritaprevir/r - Ombitasvir, ± Dasabuvir, ± Ribavirin in Participants With Chronic Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Paritaprevir/ritonavir/ombitasvir|DRUG: Dasabuvir|DRUG: Ribavirin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: XERECEPT® (hCRF) for Patients Requiring Dexamethasone to Treat Edema Associated With Brain Tumors
Status: COMPLETED
Conditions: Brain Edema|Brain Tumor
Interventions: DRUG: hCRF|DRUG: placebo hCRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thalidomide Low Threshold in Epilepsy
Status: COMPLETED
Conditions: Refractory Epilepsy
Interventions: DRUG: 3-phthalimidoglutarimide (Thalidomide)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of Safety,Tolerability,Pharmacokinetics,Food Effect& Pharmacodynamics of Single & Multiple Doses of P11187
Status: UNKNOWN
Conditions: Overweight|Diabetes Mellitus Type 2 in Obese
Interventions: DRUG: P11187|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of MP470 in Combination With Standard-of-Care Chemotherapy Regimens to Treat Solid Tumors
Status: COMPLETED
Conditions: Malignant Disease
Interventions: DRUG: MP-470 + topotecan|DRUG: MP-470 + docetaxel|DRUG: MP-470 + erlotinib|DRUG: MP-470 + paclitaxel/carboplatin|DRUG: MP-470 + carboplatin/etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Individualized Diagnosis and Treatment for Major Depressive Disorder With Atypical Features
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DRUG: SSRIs/SNRIs (Selective Serotonin Reuptake Inhibitors/ Serotonin and Norepinephrine Reuptake Inhibitors)|DRUG: SSRIs/SNRIs+Mood Stabilizer|DRUG: SSRIs/SNRIs+Quetiapine|DRUG: Usual Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Colloid and Crystalloid on the Microcirculatory Alterations During Off-pump Coronary Artery Bypass Surgery
Status: COMPLETED
Conditions: Cardiac Surgery
Interventions: DRUG: plasmalyte solution|DRUG: Hextend
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Infusion With ERAS Protocol for Pancreatic Cancer Surgery: Effect on Pain and Patient Immunity.
Status: COMPLETED
Conditions: ERAS|Lidocaine|Cancer of Pancreas|Natural Killer Cell Cytokine Production
Interventions: DRUG: Lidocaine IV|OTHER: saline IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Anticoagulation Length of ThErapy and Risk of New Adverse evenTs In Venous thromboEmbolism Study
Status: COMPLETED
Conditions: Venous Thromboembolism|Anticoagulants and Bleeding Disorders
Interventions: DRUG: Oral Anticoagulant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quercus Ilex and Quercus Robur Allergen Extracts Standardisation
Status: UNKNOWN
Conditions: Allergic Reaction|Allergic Skin Reaction|Allergy Pollen
Interventions: OTHER: Allergenic extract
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Umbilical Cord Blood in the Treatment of Stroke in Children.
Status: WITHDRAWN
Conditions: Arterial Ischemic Stroke (AIS) in Children
Interventions: BIOLOGICAL: Autologous Human Cord Blood derived Stem Cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subacromial Injections for Shoulder Subacromial Pain Syndrome - Anterolateral vs Posterior Approach
Status: UNKNOWN
Conditions: Shoulder Subacromial Pain Syndrome
Interventions: PROCEDURE: Anterolateral subacromial steroid injection|PROCEDURE: Posterior subacromial steroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Observation of 1064-nm Q-Switched Fractional Laser Combined With Oral Tranexamic Acid on Treating of Melasma.
Status: COMPLETED
Conditions: Melasma
Interventions: DRUG: tranexamic acid|RADIATION: 1064-nm Q-Switched fractional laser|RADIATION: 1064-nm Q-Switched laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-EGFR-immunoliposomes Loaded With Doxorubicin in Patients With Advanced Triple Negative EGFR Positive Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: anti-EGFR-IL-dox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between IVI of Ranibizumab With and Without Prior ACP in Patients With DME Using OCT-A
Status: RECRUITING
Conditions: Diabetic Macular Edema
Interventions: DRUG: intra-vitreal injection of Ranibizumab|PROCEDURE: anterior chamber paracentesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Side to Side Gastrojejunostomy on the Rate of Delayed Gastric Emptying After Pancreaticoduodenectomy (IPAD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Surgical Technique
Interventions: PROCEDURE: Reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effectiveness of Early or Delayed Addition of Hydroxyurea to a Three-Drug Anti-HIV Drug Combination Including Didanosine, in Advanced HIV Patients Who Failed a First or Second Anti-HIV Triple-Drug Therapy
Status: WITHDRAWN
Conditions: HIV Infections
Interventions: BIOLOGICAL: Tetanus Toxoid Vaccine|DRUG: Hydroxyurea|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of ride-on Car Training and Locomotor Experience in Toddlers With Different Motor Delays
Status: COMPLETED
Conditions: Mobility Limitation
Interventions: BEHAVIORAL: A Ride-on Car with a Standing Posture|BEHAVIORAL: Regular Therapy Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Treatment of Urolithiasis Between Disposable and Reusable Ureteroscope
Status: COMPLETED
Conditions: Kidney Calculi|Ureter Calculi
Interventions: DEVICE: reusable fiberoptic ureteroscope|DEVICE: disposable digital ureteroscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Pembrolizumab (MK-3475) in Participants With Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL) (MK-3475-A33/KEYNOTE-A33)
Status: COMPLETED
Conditions: Lymphoma, B-Cell
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Non-invasive Methods of Lung Ventilation in Patients With Respiratory Failure After Cardiac Surgery
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: PROCEDURE: Using of non-invasive mask ventilation, high-flow oxygen therapy through a nasal cannula (high-flow nasal oxygenation) and non-invasive ventilation with a helmet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Inactivated SARS-CoV-2 Vaccine (Vero Cells) in Healthy Population Aged 3 to 17 Years(COVID-19)
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: SARS-CoV-2 Vaccine (Vero Cells), Inactivated|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Oral Clofarabine in Chronic Lymphocytic Leukemia (CLL)
Status: WITHDRAWN
Conditions: Leukemia|Chronic Lymphocytic Leukemia
Interventions: DRUG: Oral Clofarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cannabinoid Control of Fear Extinction Neural Circuits in Post-traumatic Stress Disorder
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: DRUG: Dronabinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Camouflage on the Life Quality of Patients With Vitiligo
Status: UNKNOWN
Conditions: Quality of Life
Interventions: COMBINATION_PRODUCT: CapulinTM|OTHER: Chinese version of the vitiligo life quality index, VLQI-C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Prospective Study for the Treatment of Children With Newly Diagnosed LCH Using a Cytarabine Contained Protocol
Status: RECRUITING
Conditions: Langerhans Cell Histiocytosis
Interventions: DRUG: Prednisone+Cytarabine+vincristine|DRUG: Prednisone+Cytarabine+vincristine+Mercaptopurine|DRUG: Prednisone+Cytarabine+vincristine+Mercaptopurine|DRUG: Prednisone+Cytarabine+vincristine|DRUG: Prednisone+vincristine+Mercaptopurine|DRUG: Prednisone+vincristine|DRUG: Prednisone+vincristine|OTHER: Local therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Phase III Trial of Stereotactic Ablative Radiotherapy for Patients With Up to 10 Oligometastases and a Synchronous Primary Tumor.
Status: RECRUITING
Conditions: Metastatic Tumor
Interventions: RADIATION: Palliative Radiotherapy|DRUG: Chemotherapy|DRUG: Hormone therapy|DRUG: Immunotherapy|DRUG: Targeted Systemic Therapy|OTHER: Observation|RADIATION: Stereotactic Ablative Radiotherapy|PROCEDURE: Surgery|OTHER: Radiofrequency Therapy (RFA)|RADIATION: Fractionated Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Qi Zhi Tong Luo Capsule in Vascular Cognitive Impairment
Status: COMPLETED
Conditions: Vascular Cognitive Impairment|Qi Zhi Tong Luo Capsule|Randomized Controlled Trial
Interventions: DRUG: Qi Zhi Tong Luo capsule|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Double-blind, Double-dummy Study of Desloratadine (DL) 5 mg Once Daily, Cetirizine 10 mg Once Daily, and Placebo Once Daily in Patients With Chronic Idiopathic Urticaria (Study P03736)
Status: TERMINATED
Conditions: Urticaria
Interventions: DRUG: Desloratadine|DRUG: Cetirizine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Remineralizing Efficacy of Combination Varnishes on White Spot Lesions in ECC Children
Status: COMPLETED
Conditions: Child|Early Childhood Caries
Interventions: COMBINATION_PRODUCT: Sodium Fluoride with CPP-ACP varnish|COMBINATION_PRODUCT: sodium fluoride with ACP varnish|DRUG: 5% Sodium Fluoride Varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Platelet Rich Plasma on Photoaged Skin
Status: ACTIVE_NOT_RECRUITING
Conditions: Photoaging
Interventions: DEVICE: Harvest PRP Separation System|OTHER: Sterile Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Effect of Tryptophan Rich Diet and Acupuncture on Depression Related to Premenstrual Dysphoric Disorder
Status: NOT_YET_RECRUITING
Conditions: Premenstrual Dysphoric Disorder
Interventions: OTHER: Acupuncture|OTHER: Tryptophan-Rich Diet|OTHER: Vitamin B6 Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Effectiveness(Immunogeneicity) and Safety of 'GC1107' Administered Intramuscularly in Healthy Adults
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: BIOLOGICAL: GC1107|BIOLOGICAL: Tetanus and Diphtheria(Td vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Gadobutrol Pharmacokinetic and Safety Study in Pediatric Subjects Aged <2 Years (Term Newborn Infants to Toddlers 23 Months of Age Inclusive)
Status: COMPLETED
Conditions: Magnetic Resonance Imaging
Interventions: DRUG: Gadobutrol (Gadavist, BAY86-4875)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Selinexor Plus R-CHOP in High-risk GCB-subtype Diffuse Large B-Cell Lymphoma
Status: RECRUITING
Conditions: DLBCL Germinal Center B-Cell Type
Interventions: DRUG: Selinexor|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial of Donor- Derived 19-28z CAR T Cells Following Allogeneic Transplant for the Treatment of CD19 Malignancies
Status: WITHDRAWN
Conditions: Leukemia|Lymphoma|Lymphoma, B-Cell
Interventions: BIOLOGICAL: CAR T-Cell Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT