pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: An Observational Study to Learn More About How Safe Rivaroxaban is And How Well it Works in Children With Congenital Heart Disease Who Had a Heart Surgery Called the Fontan Procedure
Status: RECRUITING
Conditions: Prevention of Venous Thromboembolism|Congenital Heart Disease|Fontan Procedure|Children
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MenABCWY Noninferiority Study in Healthy Participants ≥10 to <26 Years of Age
Status: COMPLETED
Conditions: Meningococcal Vaccine
Interventions: BIOLOGICAL: MenABCWY|BIOLOGICAL: Saline|BIOLOGICAL: Trumenba|BIOLOGICAL: MenACWY-CRM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I Open Label Study of the Safety and Tolerability of Elotuzumab (BMS-901608) Administered in Combination With Either Lirilumab (BMS-986015) or Urelumab (BMS-663513) in Subjects With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Elotuzumab|DRUG: Lirilumab|DRUG: Urelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Fragmin In The Treatment Of Neuroischaemic Foot Ulcers In Diabetic Patients (A6301086)
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: Fragmin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Trial of Vaccine Responses in Childhood Cancer Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Childhood Cancer|Multiple Diseases
Interventions: BIOLOGICAL: Immunization Schedule patients <7 years.|BIOLOGICAL: Immunization Schedule patients > or = to 7 years and <11 years of age|BIOLOGICAL: Immunization Schedule patients > or = to 11 years of age
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasal Allergen Challenge Test as a Method to Detect Clinical Reactivity Against Birch Pollen
Status: RECRUITING
Conditions: Allergic Rhinitis Due to Pollen
Interventions: DRUG: ITULAZAX 12 SQ-Bet|DRUG: Placebo tablet|DRUG: Nacl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Study on the Use of Symbios Xenograft for Sinus Floor Elevation
Status: COMPLETED
Conditions: Sinus Floor Augmentation
Interventions: DEVICE: PBM+ACB|DEVICE: ABB+ACB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: QUIREDEX: Revlimid (Lenalidomide) and Dexamethasone (ReDex) Treatment Versus Observation in Patients With Smoldering Multiple Myeloma With High Risk of Progression
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: PROCEDURE: Maintenance with lower doses of lenalidomide and dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suture-based, Minimally Invasive Technique Used to Correct NSD
Status: TERMINATED
Conditions: Nasal Septum; Deviation, Congenital|Nasal Obstruction
Interventions: PROCEDURE: Suture-Septoplasty|DEVICE: Surgical suture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cell Therapy in Severe Chronic Ischemic Heart Disease
Status: COMPLETED
Conditions: Chronic Ischemic Heart Disease|Coronary Artery Disease|Angina Pectoris
Interventions: PROCEDURE: Cell Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Upgrading of the Resuscitative Patterns by Utilization of the Balanced Crystalloids and Synthetic Colloids and the Non-Invasive Hemodynamic Monitoring During Burn Shock
Status: UNKNOWN
Conditions: Burns|Shock
Interventions: DEVICE: LIDCO Lithium Dilution Cardiac Output|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: EUS-GE vs ES for Palliation of Gastric Outlet Obstruction
Status: RECRUITING
Conditions: Gastric Outlet Obstruction
Interventions: DEVICE: Lumen-apposing metal stent|DEVICE: Self-expandable metal stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Does IV Magnesium Improve Quality of Recovery With ERAS Protocols in Laparoscopic Colorectal Surgery?
Status: COMPLETED
Conditions: Colo-rectal Cancer|Anesthesia
Interventions: DRUG: IV Medications|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of a Tetravalent Dengue Vaccine in Healthy Adults in Australia
Status: COMPLETED
Conditions: Dengue Fever|Dengue Hemorrhagic Fever
Interventions: BIOLOGICAL: Live, attenuated, recombinant dengue serotypes 1, 2, 3, & 4 virus|BIOLOGICAL: Live, attenuated, recombinant dengue serotypes 1, 2, 3, & 4 virus|BIOLOGICAL: Live, attenuated, recombinant dengue serotypes 1, 2, 3, & 4 virus|BIOLOGICAL: Live, attenuated, recombinant dengue serotypes 1, 2, 3, & 4 virus|BIOLOGICAL: Placebo: NaCl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Peri-implant Tissue Stability Following Tissue Augmentation Harvested From Deep Palate or Tuberosity
Status: UNKNOWN
Conditions: Alveolar Ridge Augmentation|Tissue Transplantation|Tissue Donors
Interventions: PROCEDURE: connective tissue graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Anlotinib Combined With Docetaxel in EGFR Mutations Advanced Non Small Cell Lung Cancer Patients
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Anlotinib Hydrochloride plus Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dopamine D2/D3 Receptor Upregulation by Varenicline in Methamphetamine Users
Status: TERMINATED
Conditions: Dopamine D2/3 Receptor Availability|Cognitive Function|Methamphetamine Abuse
Interventions: DRUG: Varenicline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Coaching for Coping in Glioblastoma Patients and Caregivers and Its Association With Compliance to TTFields
Status: NOT_YET_RECRUITING
Conditions: Compliance, Patient|Glioblastoma|Astrocytoma, Grade IV
Interventions: OTHER: Psychological intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase II/III Clinical Study CSF470 Plus BCG Plus GM-CSF vs IFN Alpha 2b in Stage IIB, IIC and III Melanoma Patients
Status: UNKNOWN
Conditions: Cutaneous Melanoma
Interventions: BIOLOGICAL: CSF470 vaccine, BCG, Molgramostim|DRUG: interferon alpha 2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Nutraceutical Supplement With Standardized Botanicals in Males With Self-Perceived Thinning Hair and Loss
Status: TERMINATED
Conditions: Hair Loss|Hair Thinning
Interventions: DIETARY_SUPPLEMENT: Oral Nutraceutical Supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Clinical Trial of the TANTALUS® System in Treatment of Obese to Morbidly Obese Patients
Status: COMPLETED
Conditions: Type 2 Diabetes|Obesity
Interventions: DEVICE: rechargeable TANTALUS II
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endometrial Receptivity After GnRH Agonist Triggering
Status: COMPLETED
Conditions: Ovarian Hyperstimulation Syndrome
Interventions: DRUG: hCG|DRUG: triptorelin|DRUG: Triptorelin, estradiol valerate, micronized vaginal progesterone|DRUG: triptorelin, hCG|DRUG: triptorelin, hCG|DRUG: triptorelin, recombinant LH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sibutramine Versus Continuous Positive Airway Pressure (CPAP)in Obstructive Sleep Apnea (OSA) Patients
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Obesity|Hypertension
Interventions: DRUG: Sibutramine|DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ROTAHALER Device Optimization Study
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone Propionate / Salmeterol Xinafoate DISKUS|DRUG: Fluticasone Propionate / Salmeterol Xinafoate ROTACAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Investigate The Safety And Toleration Of A Single Dose Of PF-04418948 In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-04418948|DRUG: PF-04418948|DRUG: PF-04418948|DRUG: PF-04418948|DRUG: PF-04418948|DRUG: PF-04418948|DRUG: PF-04418948
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Does Pre-operative Patients' Education Facilitates Emergence of Anesthesia Following Bariatric Surgery?
Status: UNKNOWN
Conditions: Obesity
Interventions: BEHAVIORAL: pre operative education|BEHAVIORAL: pre operative education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia (FETO)
Status: RECRUITING
Conditions: Congenital Diaphragmatic Hernia|Pulmonary Hypoplasia|Pulmonary Artery Hypertension
Interventions: DEVICE: BALT GoldbBAL2 Detachable Balloon|DEVICE: Catheter System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of T89 in Prevention and Treatment of Adults With Acute Mountain Sickness (AMS)
Status: COMPLETED
Conditions: Acute Mountain Sickness (AMS)
Interventions: DRUG: T89 capsule|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Acupuncture on the Complications of Cerebral Vascular Accident
Status: TERMINATED
Conditions: Stroke
Interventions: PROCEDURE: acupuncture(44mm in length and 32-gauge)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind, Placebo-controlled Crossover Study of Repeat Rivastigmine Administration in Healthy Male Volunteers
Status: COMPLETED
Conditions: Rivastigmine Toxicity
Interventions: DRUG: Rivastigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of NNS on Metformin/GDF15, Pilot
Status: COMPLETED
Conditions: Obesity, Adolescent|Pre Diabetes
Interventions: BEHAVIORAL: avoid sugary and NNS drinks plus start Metformin|BEHAVIORAL: avoid sugary drinks (allowed water and drinks sweetened with NNS) plus start Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Valsartan in Combination With Amlodipine Compared to Losartan Plus Hydrochlorothiazide in Patients With Hypertension and Left Ventricular Hypertrophy
Status: COMPLETED
Conditions: Hypertension; Hypertrophy, Left Ventricular
Interventions: DRUG: Valsartan|DRUG: Amlodipine|DRUG: Hydrochlorothiazide|DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Azelaic Acid Foam, 15 % in Papulopustular Rosacea
Status: COMPLETED
Conditions: Papulopustular Rosacea
Interventions: DRUG: Azelaic acid foam, 15% (BAY39-6251)|DRUG: Vehicle foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: American Ginseng in Treating Patients With Fatigue Caused by Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Fatigue|Leukemia|Lymphoma|Lymphoproliferative Disorder|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Precancerous Condition|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: American ginseng|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ANDRO 2002: Dehydroepiandrosterone (DHEA) or Testosterone Versus Placebo in Men With Sexual Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: DHEA|DRUG: Testosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of Enteral Nutrition Versus Paranteral Nutrition in Hematopoietic Stem Cell Transplant Patients: A Pilot Randomized Controlled Study
Status: RECRUITING
Conditions: Stem Cell
Interventions: DIETARY_SUPPLEMENT: Enteral nutrition (EN)|OTHER: Standard care parenteral nutrition (PN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Minerva Pivotal Study to Evaluate Safety and Efficacy of the Aurora Endometrial Ablation System Compared to Hysteroscopic Rollerball Ablation
Status: COMPLETED
Conditions: Menorrhagia
Interventions: DEVICE: Aurora Endometrial Ablation|DEVICE: Rollerball Ablation/Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MP0420 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: MP0420|DRUG: Placebo|BIOLOGICAL: Remdesivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Ropivacaine Plus Fentanyl vs Ropivacaine for Continuous 3-in-1 FNB After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Femoral nerve block with ropivacaine+fentanyl|DRUG: Femoral nerve block with ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Impact of Endoscopic Pituitary Surgery on Nasal Function
Status: UNKNOWN
Conditions: Pituitary Tumor|Endoscopic Surgery|Quality of Life|Function of Nose
Interventions: PROCEDURE: Single nostril approach endoscopic transsphenoidal pituitary surgery|PROCEDURE: Bilateral nostril approach endoscopic transsphenoidal pituitary surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cytoscopic Antibiotic Irrigant to Reduce Postoperative Urinary Tract Infection
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DRUG: Cystoscopic Fluid containing Neosporin G. U. Irrigant|PROCEDURE: Cystoscopy|DRUG: Cystoscopic Fluid/Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Behavior Therapy for Insomnia Delivered by a Therapist or on the Internet
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: Internet CBT-i SHUTi|BEHAVIORAL: face-to-face CBT-i
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact Of Nutritional Education Program In Hemodialysis Patients
Status: NOT_YET_RECRUITING
Conditions: Hemodialysis Complication
Interventions: DIETARY_SUPPLEMENT: Natritional Education Program In Hemodialysis Patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Compare the Addition of Umeclidinium Bromide (UMEC) to Fluticasone Furoate (FF)/Vilanterol (VI), With Placebo Plus FF/VI in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: FF|DRUG: VI|DRUG: UMEC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study of Repeated Intravenous E6011 Administration in Japanese Subjects With Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: E6011 2 mg/kg|DRUG: E6011 5 mg/kg|DRUG: E6011 10 mg/kg|DRUG: E6011 15 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: RADIAL Versus Femoral Access for Coronary Artery Bypass Graft Angiography and Intervention (RADIAL-CABG) Trial
Status: COMPLETED
Conditions: Vascular Access Complication
Interventions: PROCEDURE: Radial access versus femoral access for coronary angiography and intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness and Safety Study of Solifenacin Succinate and Solifenacin Succinate + Estrogen to Treat OAB in Postmenopausal Women
Status: COMPLETED
Conditions: Overactive Bladder|Postmenopausal Disorder|Urination Disorders
Interventions: DRUG: Solifenacin Succinate Tablets|DRUG: Estrogen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnosis of Ventilator- Associated Pneumonia in Children: A Comparative Study of Bronchoscopic and Non-Bronchoscopic Methods
Status: COMPLETED
Conditions: Ventilator Associated Pneumonia
Interventions: PROCEDURE: bronchoaleolar lavage|PROCEDURE: Bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Low Dose Interferon Alpha Versus Hydroxyurea in Treatment of Chronic Myeloid Neoplasms
Status: COMPLETED
Conditions: Polycythemia Vera|Essential Thrombocythemia|Primary Myelofibrosis
Interventions: DRUG: PegIntron|DRUG: Pegasys|DRUG: PegIntron|DRUG: Pegasys|DRUG: Hydrea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial of Sofosbuvir in Combination With Daclatasvir or Simeprevir for 12 Weeks in Non-cirrhotic Subjects Infected With Chronic Hepatitis C Virus Genotype 1 (TNT)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Daclatasvir + Sofosbuvir|DRUG: Simeprevir + Sofosbuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: WALTZ - Wet Age-Related Macular Degeneration (AMD) AL-39324 Treatment Examination
Status: COMPLETED
Conditions: Age Related Macular Degeneration
Interventions: DRUG: AL-39324 ophthalmic suspension|DRUG: Ranibizumab 10 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Efficacy and Safety of X0002 in Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: KNEE OSTEOARTHRITIS
Interventions: DRUG: X0002 Spray|DRUG: Celecoxib capsules|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Degarelix in the Treatment of Endometriosis Recurrence
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: degarelix|DRUG: Leuprolide Acetate 11.25 MG/ML (Enantone 11,25)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of MK-0476 in Japanese Pediatric Participants With Seasonal Allergic Rhinitis (MK-0476-519)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Montelukast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Everolimus-Eluting Stent vs Sirolimus-Eluting Stent in Patients With DIABETES Mellitus
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: XIENCE V|DEVICE: CYPHER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pan-genome Analysis of Neuroblastoma by Comparative Genomic Hybridization and Correlation With Pathology for the Diagnostic and the Prognostic Classification
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: PROCEDURE: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tocolysis in the Management of Preterm Premature Rupture of Membranes Before 34 Weeks of Gestation
Status: RECRUITING
Conditions: Preterm Premature Rupture of Membrane
Interventions: DRUG: Nifedipine|DRUG: Placebo of Nifedipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid Biochemical Diagnostics of Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury|Concussion, Mild|Bone Fracture
Interventions: DIAGNOSTIC_TEST: Sample collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Comparison of Postprandial Glucose After a MMTT, and the Metabolic Effects of Insulin Withdrawal in a Crossover Study in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Type1diabetes|Diabetes Mellitus
Interventions: DRUG: YG1699|DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gene Therapy to Improve Wound Healing in Patients With Diabetes
Status: COMPLETED
Conditions: Wounds and Injuries|Diabetes|Diabetic Foot Ulcers|Foot Wounds
Interventions: GENETIC: GAM501
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of Eltrombopag in Healthy Subjects and Volunteers With Mild, Moderate or Severe Hepatic Impairment
Status: COMPLETED
Conditions: Purpura, Thrombocytopaenic, Idiopathic
Interventions: DRUG: eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of n-3 Fatty Acid Supplementation in Hyperlipidemic Patients Taking Statins
Status: COMPLETED
Conditions: Cardiovascular Diseases|Hyperlipidemias|Dyslipidemias
Interventions: DIETARY_SUPPLEMENT: EPA+DHA|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Unruptured Intracranial Aneurysm Aspirin Trial (UIAAT).
Status: UNKNOWN
Conditions: Intracranial Aneurysm|Inflammation
Interventions: DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2330672 in Type 2 Diabetes Patients Taking Metformin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: GSK2330672|DRUG: Placebo|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Sunitinib as First-Line Therapy in Treating Patients With Stage IV Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Lung Cancer
Interventions: DRUG: paclitaxel albumin-stabilized nanoparticle formulation|DRUG: sunitinib malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Specific CD4 Tumors Th1 Responses in Renal Transplant After Occurrence of Cancer
Status: UNKNOWN
Conditions: Disorder Related to Renal Transplantation|Cancer
Interventions: OTHER: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Telepsychotherapy for the Treatment of Adolescents With Trichotillomania
Status: UNKNOWN
Conditions: Trichotillomania
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy Enhanced Behavior Therapy (AEBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Canine Retraction Using Different Bracket Slots' Sizes
Status: UNKNOWN
Conditions: Treating Class II Malocclusion and Bimaxillary Proclination
Interventions: DEVICE: Orthodontic brackets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Risk Reduction Program in Preventing the Transmission of HIV and Sexually Transmitted Diseases in African-American Couples
Status: COMPLETED
Conditions: HIV Infections|Sexually Transmitted Disease
Interventions: BEHAVIORAL: Eban HIV/STD Risk Reduction Intervention|BEHAVIORAL: Eban Health Promotion Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: A Trial of Chronotherapy of Corticosteroids in Duchenne Muscular Dystrophy
Status: WITHDRAWN
Conditions: Duchenne Muscular Dystrophy (DMD)
Interventions: DRUG: Prednisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Safety and Efficacy Study of BLI-1300 Ointment in Symptomatic Perianal Crohn's Disease
Status: TERMINATED
Conditions: Perianal Crohn's Disease
Interventions: DRUG: BLI-1300 low dose|DRUG: BLI-1300 high dose|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Pharmacokinetics of Mometasone Furoate Alone and in Combination With Indacaterol in Patients ≥ 6 to < 12 Years Old With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Mometasone furoate|DRUG: QMF149|DRUG: Standard of Care (Soc)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study to Evaluate the Efficacy of Regorafenib in Specific GIST Mutation Subsets (KIT Exon 17, 18, or 14 Mutation and SDHB Deficient GIST) in the Post-imatinib Second-line Setting.
Status: RECRUITING
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-occlusive Reactive Hyperemia and Basal-cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Basal Cell
Interventions: PROCEDURE: BCC surgery|OTHER: Tourniquet ischemia|OTHER: Laser speckle imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Multiple Dose Study to Investigate Safety, Tolerability and Pharmacokinetics of MN-08 Tablets
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: MN-08 24 mg/day|DRUG: MN-08 60 mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Multicenter Study on Best Clinical Use of Imatinib in the Advanced Gastrointestinal Stromal Tumors
Status: COMPLETED
Conditions: Advanced Gastrointestinal Stromal Tumors
Interventions: DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-articular Allocetra in Osteoarthritis of the 1st Carpo-metacarpal Joint
Status: RECRUITING
Conditions: Osteoarthritis Thumb
Interventions: DRUG: Allocetra - Safety run-in phase|OTHER: Placebo|DRUG: Allocetra - Randomization phase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Implant Using "Nanobone" Versus "Autogenous Bone" for Treatment of Patients With Unrestorable Single Tooth.
Status: COMPLETED
Conditions: Immediate Implant With Bone Graft
Interventions: PROCEDURE: Immediate implants with nanobone graft|PROCEDURE: immediate implants with autogenous bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epiglottic Downfolding During Endotracheal Intubation
Status: WITHDRAWN
Conditions: Intubation Complication|Injury of Epiglottis
Interventions: DEVICE: C-MAC® videolaryngoscope (Karl Storz, Tuttlingen, Germany)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Prehabilitation During the Neoadjuvant Window of Opportunity in Older Women With Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer|Neoadjuvant Chemotherapy|Prehabilitation
Interventions: BEHAVIORAL: FIT4SURGERY|BEHAVIORAL: Healthy Lifestyle Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Transcutaneous Electrical Nerve Stimulation on Pain During Venous Cannulation
Status: COMPLETED
Conditions: Cannulation Pain
Interventions: PROCEDURE: Transcutaneous electrical nerve stimulation (Empi, USA)|PROCEDURE: Transcutaneous electrical nerve stimulation (Empi, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intermetatarsal Bursitis in Patients With Rheumatoid Arthritis
Status: RECRUITING
Conditions: Intermetatarsal Bursitis|Rheumatoid Arthritis
Interventions: DIAGNOSTIC_TEST: Magnetic resonance imaging|DIAGNOSTIC_TEST: Ultrasound|DRUG: Corticosteroid injection|OTHER: Clinical foot evaluation|OTHER: Picture of the feet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Insulin Sensitizers Role in Control of PCOS Vicious Cycle.
Status: COMPLETED
Conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Interventions: DRUG: Metformin Hydrochloride|DRUG: MI/DCI combination in 40:1 ratio|DRUG: Combination of Metformin hydrochloride and MI/DCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vyvanse and Glucose Intolerance in Children With Attention Deficit Hyperactivity Disorder (ADHD) and Obesity
Status: TERMINATED
Conditions: Attention Deficit Hyperactivity Disorder|Glucose Intolerance|Obesity
Interventions: DRUG: Lis-dexamphetamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Strength of Maximum Glute and Medium Glutenum Muscles Of Latin and Active Lombar Guidelines
Status: COMPLETED
Conditions: Spinal Injuries|Low Back Pain
Interventions: DIAGNOSTIC_TEST: Evaluation of pain by algometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Adjuvant Effect of Dexmedetomidine in Ultrasound (USG) Guided Transvers Abdominis Plane Block
Status: WITHDRAWN
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Dexmedetomidine|DRUG: 0.25 % bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: LINK-HF2 - Remote Monitoring Analytics in Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: OTHER: Remote monitoring and predictive analytics|OTHER: Sham comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Renoprotective Effects of Dapagliflozin in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Diabetic Nephropathies
Interventions: DRUG: Dapagliflozin 10mg QD|DRUG: Gliclazide 30mg QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Computerized Single-Session Interventions for Indian Adolescents
Status: COMPLETED
Conditions: Well-being|Depression|Anxiety
Interventions: BEHAVIORAL: Growth Mindset|BEHAVIORAL: Gratitude|BEHAVIORAL: Behavioral Activation|BEHAVIORAL: Study Skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Targeting CD19/CD20/CD22 Triple-targeted Cell in Patients With Relapsed/Refractory B-cell Lymphoma
Status: RECRUITING
Conditions: B-cell Lymphoma Recurrent|B-cell Lymphoma Refractory
Interventions: BIOLOGICAL: LCAR-AIO cells product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Trimetazidine on Mitochondrial Function, Myocardial Performance, and Invasive Hemodynamics in Patients Diagnosed With Wild-Type Transthyretin Cardiac Amyloidosis
Status: COMPLETED
Conditions: Transthyretin Amyloid Cardiopathy|Mitochondrial Pathology
Interventions: DRUG: Trimetazidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Video vs. Direct Laryngoscopy in Pediatric Nasal Intubation
Status: TERMINATED
Conditions: Nasal Intubation
Interventions: DEVICE: Video Laryngoscopy for nasal intubation|DEVICE: Direct Laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combination of LTC004 and Regorafenib to Treat Patients With Advanced/Metastatic CRC
Status: NOT_YET_RECRUITING
Conditions: Advanced/Metastatic Colorectal Cancer
Interventions: DRUG: LTC004+regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of BLB-201 Vaccine in Healthy Young and Older Adults
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: CPI-RSV-F Vaccine (BLB-201)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Efficacy and Safety of Two Dosing Regimens of Alefacept in Subjects Weighing Between 100kg and 150kg With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis
Interventions: DRUG: alefacept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of FOLFOXIRI in Patients With Locally Advanced or Metastatic Biliary Tract Cancer
Status: UNKNOWN
Conditions: Biliary Tract Cancer
Interventions: DRUG: Fluorouracil|DRUG: Leucovorin|DRUG: Oxaliplatin|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics Study of Healthy Male Adults When Repeatedly Administered Through Intravenous Injection
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: GC1102|OTHER: JW normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Augmented Medial Rectus Muscle Recession Versus Posterior Scleral Fixation in Partially Accommodative Esotropia
Status: COMPLETED
Conditions: Partially Accommodative Esotropia
Interventions: PROCEDURE: augmented recession|PROCEDURE: Faden
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Hybrid Laser 10600+1540 nm on GSM
Status: UNKNOWN
Conditions: Vaginal Atrophy|Genitourinary Disease
Interventions: DEVICE: Youlaser MT Group 2|DEVICE: Youlaser MT Group 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of INTEGRA™ Flowable Wound Matrix to Manage Diabetic Foot Ulcers
Status: TERMINATED
Conditions: Diabetes|Foot Ulcer
Interventions: DRUG: INTEGRA™ Flowable Matrix (Collagen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Alirocumab in Addition to Lipid-Modifying Therapy in Patients With High Cardiovascular Risk and Hypercholesterolemia in South Korea and Taiwan
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Placebo (for Alirocumab)|DRUG: Alirocumab|DRUG: Lipid-Modifying Therapy (LMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sport Therapy and Osteopathy Manipulative Treatment in ALS
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: OTHER: Sport therapy|OTHER: Osteopathic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of AferBio® on Quality of Life and Chemotherapy Toxicity in Lung Cancer Patients
Status: UNKNOWN
Conditions: Quality of Life|Infection|Drug Toxicity
Interventions: DIETARY_SUPPLEMENT: AferBio
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluate the Maintenance of Efficacy of SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder
Status: COMPLETED
Conditions: Binge Eating Disorder
Interventions: DRUG: Lisdexamfetamine dimesylate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gene Therapy Trial for Platelet Derived Factor VIII Production in Hemophilia A
Status: RECRUITING
Conditions: Hemophilia A
Interventions: BIOLOGICAL: Auto CD34+PBSC, transduced with a lentiviral vector encoding the B domain deleted from of human coagulation factor VIII
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bariatric Surgery for Fertility-Sparing Treatment of Atypical Hyperplasia and Grade 1 Cancer of the Endometrium
Status: RECRUITING
Conditions: Endometrial Cancer|Atypical Hyperplasia|Bariatric Surgery Candidate
Interventions: PROCEDURE: Bariatric Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Maxinom® And Maxitrol® in Reducing The Signs And Symptoms Of Acute Bacterial Conjunctivitis
Status: UNKNOWN
Conditions: Bacterial Conjunctivitis|Acute
Interventions: DRUG: MAXINOM®|DRUG: Maxitrol®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tezepelumab Efficacy and Safety in Reducing Oral Corticosteroid Use in Adults With Oral Corticosteroid Dependent Asthma
Status: RECRUITING
Conditions: Asthma
Interventions: BIOLOGICAL: Tezepelumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Total Lymphoid Irradiation as Conditioning for Pediatric Haploidentical Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Hematopoietic Organs; Disorder
Interventions: RADIATION: Total lymphoid irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Clinical Trial to Evaluate the Biological Activity of Fulvestrant in Breast Ductal Carcinoma in Situ (DCIS)
Status: TERMINATED
Conditions: Breast Carcinoma
Interventions: DRUG: Tamoxifen|DRUG: Fulvestrant|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Therapy of Sintilimab Combined With Chemotherapy for Resectable Squamous Cell NSCLC（neoSCORE Ⅱ）
Status: RECRUITING
Conditions: Squamous Cell Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Sintilimab|DRUG: Carboplatin|DRUG: Albumin-Bound Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of the Site for Growth Factor Injection for Patients Undergoing Autologous Stem Cell Transplantation
Status: TERMINATED
Conditions: Cytokines
Interventions: DRUG: G-CSF, GM-CSF administered at extremities|DRUG: G-CSF and GMCSF administered at abdomen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single and Two-visit Pulpectomy in Primary Molars
Status: NOT_YET_RECRUITING
Conditions: Dental Pulp Necroses
Interventions: PROCEDURE: Single and two visits pulpectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Ultrasound in Diagnosing Cancer in Patients With Localized Stomach Cancer or Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: cisplatin|DRUG: fluorouracil|OTHER: questionnaire administration|PROCEDURE: diagnostic endoscopic procedure|PROCEDURE: neoadjuvant therapy|PROCEDURE: quality-of-life assessment|PROCEDURE: therapeutic conventional surgery|PROCEDURE: therapeutic endoscopic surgery|PROCEDURE: ultrasound imaging|RADIATION: radiation therapy|RADIATION: radioisotope therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Influence of IPV on GOR in Infants From 0 to 12 Months.
Status: COMPLETED
Conditions: Gastro-oesophageal Reflux
Interventions: DEVICE: Intrapulmonary Percussive Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Exercise and Education in Neurophysiology of Pain in the Quality of Life of Women With Endometriosis
Status: RECRUITING
Conditions: Endometriosis
Interventions: OTHER: Physiotherapy|OTHER: Sham, Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application of AI Technology for the Diagnosis and Treatment of Geriatric Diseases
Status: RECRUITING
Conditions: Parkinson Disease|Alzheimer Disease|Nervous System Diseases|Geriatric Diseases
Interventions: OTHER: Handwriting, gait, speech, eye movements, biological samples (blood, urine, stool, saliva, etc.), images, EEG, and other relevant markers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p