pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effectiveness of Muscle Energy Technique and Friction Massage in Hamstring Tightness Amongst Young Athletes of Pakistan
Status: COMPLETED
Conditions: Hamstring Tightness|Hamstring Injury Prevention
Interventions: OTHER: Post Facilitation Stretch|OTHER: Post Isometric Relaxation|OTHER: Friction Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Safety and Efficacy of Calcitonin Gene-Related Peptide (CGRP) Antagonists in Patients With Dry Eye Disease and Asthenopia
Status: COMPLETED
Conditions: Dry Eye|Asthenopia
Interventions: DRUG: Injection for SC administration (120mg/syringe)|DRUG: Tablet (50mg/tablet), oral
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of High-intensity Intermittent Games on Cardiorespiratory Fitness and Body Composition in Children
Status: UNKNOWN
Conditions: Children, Physical Activity
Interventions: BEHAVIORAL: High-intensity intermittent games|BEHAVIORAL: Moderate intensity games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Relative Bioavailability of Two Orally Administered CBD Formulations in Healthy Male Adults
Status: RECRUITING
Conditions: Pharmacokinetics
Interventions: DRUG: Cannabidiol|DRUG: Cannabidiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Evaluation of the Effects of a Non-Caffeinated Energy Dietary Supplement
Status: COMPLETED
Conditions: Health Behavior
Interventions: DIETARY_SUPPLEMENT: Phytovive|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Randomized Sham-control Auricular TENS Unit Stimulation in Pediatric Functional Gastrointestinal Disorders
Status: TERMINATED
Conditions: Functional Gastrointestinal Disorders|Vagus Nerve Autonomic Disorder|Irritable Bowel Syndrome|Nausea|Dyspepsia
Interventions: DEVICE: Transcutaneous Electrical Nerve Stimulation (TENS)|DEVICE: Sham Transcutaneous Electrical Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Aerobic Exercise Added to Alprazolam in Panic Disorder Treatment
Status: COMPLETED
Conditions: Panic Disorder
Interventions: DRUG: Alprazolam|DRUG: Alprazolam + Aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics for Chalaziosis Treatment in Children
Status: COMPLETED
Conditions: Chalazion
Interventions: DIETARY_SUPPLEMENT: probiotics|OTHER: conservative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Physical Activity Counseling in Patients With Adolescent Idiopathic Scoliosis
Status: UNKNOWN
Conditions: Scoliosis|Adolescent Scoliosis
Interventions: OTHER: Scoliosis Specific Corrective Exercises and Physical Activity Counseling|OTHER: Scoliosis Specific Corrective Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Subcutaneous Risankizumab Injection for Pediatric Participants With Moderate to Severe Plaque Psoriasis to Assess Change in Disease Symptoms
Status: ACTIVE_NOT_RECRUITING
Conditions: Psoriasis
Interventions: DRUG: Risankizumab|DRUG: Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Blended Sensor Efficiency on Relieving the Heart's Inability to Increase Its Rate During Exercise
Status: TERMINATED
Conditions: Chronotropic Incompetence
Interventions: DEVICE: Blended Sensor Optimization (BSO)|DEVICE: Accelerometer Alone (AA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Physiotherapist-guided Home Exercise in Moderate to Severe MS
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Physiotherapist-guided home exercise with web-based support|BEHAVIORAL: Physiotherapist-guided home exercise with standard support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of AR-12286 in Patient With Elevated Intraocular Pressure (IOP)
Status: COMPLETED
Conditions: Elevated Intraocular Pressure
Interventions: DRUG: AR-12286|DRUG: AR-12286 vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Magnetic Resonance Imaging Guided Radiotherapy Dose Adaptation in Human Papilloma Virus Positive Oropharyngeal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Neoplasms of Lip Oral Cavity and Pharynx|Oropharyngeal Cancer
Interventions: PROCEDURE: Modified Barium Swallow (MBS)|BEHAVIORAL: Swallowing Questionnaire|BEHAVIORAL: Symptom Questionnaire|PROCEDURE: Video-Strobe Procedure|PROCEDURE: MRI Guided Intensity Modulated Radiotherapy (IMRT) Planning|PROCEDURE: Standard-of-Care Intensity Modulated Radiotherapy (IMRT) Planning|RADIATION: Intensity Modulated Radiotherapy (IMRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corneal Epithelial Autograft for Pterygium
Status: UNKNOWN
Conditions: Pterygium
Interventions: PROCEDURE: Corneal epithelial autograft|PROCEDURE: Limbal conjunctival autograft|PROCEDURE: Simple removal|DEVICE: Diamond knife|DEVICE: Femtosecond laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the Click Sexual Health Test for the Detection of Neisseria Gonorrhoeae (NG), Trichomonas Vaginalis (TV), and Chlamydia Trachomatis (CT) in Women
Status: COMPLETED
Conditions: Chlamydial Infection|Gonococcal Infection|Trichomoniasis
Interventions: DIAGNOSTIC_TEST: Click Sexual Health Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2a, Dose-Ranging Study to Evaluate the Safety, Pharmacokinetics and Efficacy of VX-135 With Ribavirin in Treatment-Naïve Subjects With Chronic Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: VX-135|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of Maternal Serum Pentraxin 3 (PTX 3) and Heparin-binding Protein (HBP) for Chorioamnionitis in Preterm Premature Rupture of Membranes
Status: UNKNOWN
Conditions: Preterm Premature Rupture of Membrane
Interventions: OTHER: The concentrations of PTX3 and HBP were monitored in maternal blood, placental tissue and amniotic fluid.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lactate Profile and Fat Oxidation During Exercise
Status: COMPLETED
Conditions: Energy Metabolism
Interventions: OTHER: Incremental exercise test|OTHER: Incremental exercise test under hyperthermia|OTHER: Incremental exercise test under glycogen depletion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lymphedema Prophylaxis in Breast Cancer Survivors Who Show Early Evidence of High-risk Status
Status: COMPLETED
Conditions: Lymphedema|Breast Cancer
Interventions: DEVICE: Flexitouch|DEVICE: Class 1 compression garment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: EPO-BUL-01 - Study of the Optimization of Anemia Management of EPREX (Epoetin Alfa) in Predialysis Patients With Chronic Renal Failure
Status: COMPLETED
Conditions: Chronic Renal Failure
Interventions: DRUG: Epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneous CSL730 in Healthy Adult Subjects
Status: TERMINATED
Conditions: Immune Complex-mediated Autoimmune Diseases
Interventions: BIOLOGICAL: CSL730|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Pre and Peroperative Factors for MODS-2 in Pediatric Cardiac Surgery
Status: COMPLETED
Conditions: Congenital Heart Disease in Children|Cardiac Surgical Procedures|Outcome Assessment|Organ Dysfunction Scores
Interventions: PROCEDURE: Pediatric cardiac surgery with cardiopulmonary bypass
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exploring the Health Effects of Group Game-based Activities on Individuals With Chronic Mental Illness
Status: ENROLLING_BY_INVITATION
Conditions: Chronic Mental Illness|Schizophrenia|Psychiatry
Interventions: BEHAVIORAL: group gamed-based activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acotral® Versus Zetia® Ezetimibe Bioequivalance Study.
Status: COMPLETED
Conditions: Hypercholesterolaemia
Interventions: DRUG: 10mg Ezetimibe|DRUG: 10 mg Ezetimibe - wash out period
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: SToRytelling to Improve DiseasE Outcomes in GOut: The STRIDE-GO2 Study
Status: COMPLETED
Conditions: Gout|Low Medication Adherence|Health Related Quality of Life
Interventions: BEHAVIORAL: Gout Storytelling Video Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Safety, Tolerability, Pharmacokinetics and 5 HT1A Receptor Occupancy
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: SRA-444
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Rehabilitation Early After Stroke Using Feedback-controlled Robotics-assisted Treadmill Exercise
Status: COMPLETED
Conditions: Stroke|Cardiovascular Diseases
Interventions: DEVICE: Feedback-controlled robotics-assisted treadmill exercise|DEVICE: Robotics-assisted treadmill exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Measure the Amount of BI 425809 in the Blood When Taken as a Tablet
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 425809|DRUG: BI 425809 mixed with [C-14]-BI 425809
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 2017-03: A Single-Arm, Open-label Study of Anti-Signaling Lymphocytic Activation Molecule F7 (Anti-SLAMF7) Monoclonal Antibody (mAb) Therapy After Autologous Stem Cell Transplant in Patients With Multiple Myeloma
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: Elotuzumab|DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Assess the Influence of Dietary Organic Acids on Iron Absorption.
Status: COMPLETED
Conditions: Iron Deficiency Anaemia
Interventions: DIETARY_SUPPLEMENT: ferrous sulphate|DIETARY_SUPPLEMENT: ferric iron oxide-organic acid (Fe-OA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study To Evaluate The Safety And Effects On The Body Of An Investigational Drug Using An Endotoxin-Induced Inflammatory Response Model
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: PF-06282999|DRUG: Placebo|OTHER: LPS|DRUG: PF-06282999|DRUG: Placebo|OTHER: LPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Norwegian Tenecteplase Stroke Trial 2
Status: TERMINATED
Conditions: Stroke, Acute|Cerebrovascular Disorders|Ischemic Stroke
Interventions: DRUG: Tenecteplase|DRUG: Alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antidepressant Treatment at an Inner City Asthma Clinic
Status: COMPLETED
Conditions: Depression|Asthma
Interventions: DRUG: High severity group: Escitalopram|DRUG: High severity group: Placebo|DRUG: Low severity group: Escitalopram|DRUG: Low severity group: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: iMedA: Improving MEDication Adherence Through Person-Centered Care and Adaptive Interventions
Status: UNKNOWN
Conditions: Hypertension
Interventions: BEHAVIORAL: Reminder|BEHAVIORAL: Educational message|BEHAVIORAL: Motivational messages|BEHAVIORAL: showing trends
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Hospitalization on High-sensitivity Cardiac Troponin T Concentrations Depending on Disease Severity
Status: COMPLETED
Conditions: Non-cardiac Disease
Interventions: DIAGNOSTIC_TEST: Analysis of hs-cTnT serum concentration at hospitalization|DIAGNOSTIC_TEST: Analysis of hs-cTnT serum concentration after discharge
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Research Study to Evaluate the Effects of a New Oral Medicine Called Cenerimod in Adults With Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Lupus Erythematosus, Systemic
Interventions: DRUG: Cenerimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of DU-176b in Preventing Blood Clots in Patients Undergoing Total Hip Replacement
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Hip|Thrombosis
Interventions: DRUG: DU-176b
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Gadoxetate Abbreviated MRI in Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Liver Metastasis Colon Cancer
Interventions: DIAGNOSTIC_TEST: Full Gadoxetate-enhanced liver MRI|DIAGNOSTIC_TEST: Shortened Gadoxetate-enhanced liver MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Urinary Kallidinogenase for Large Artery Atherosclerosis Acute Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Urinary kallidinogenase for injection|OTHER: Guideline-prescribed medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of 6-Thioguanine in Combination With 6-Mercaptopurine During Maintenance Therapy of Childhood Lymphoma
Status: WITHDRAWN
Conditions: Non-Hodgkin Lymphoma
Interventions: DRUG: 6-thioguanine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapy Optimization in Multiple Sclerosis (MS)
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Glatiramer Acetate, IFN-beta 1a (IM), IFN-beta 1a (Subcutaneous), and IFN-beta 1b
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Face-to-face and Online Health Education on the Health Beliefs of Women Aged 40-69 and Their Participation in Screening
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Online training group|BEHAVIORAL: Face-to-face training group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Elastic Compression in Chronic Venous Disease
Status: UNKNOWN
Conditions: Varicosity
Interventions: DEVICE: Elastic stockings|DEVICE: Placebo stockings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Celecoxib, Ibuprofen and the Antiplatelet Effect of Aspirin
Status: COMPLETED
Conditions: Ischemic Heart Disease|Osteoarthritis
Interventions: DRUG: celecoxib|DRUG: ibuprofen|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cognitive Training to Enhance VA Work Program Outcomes
Status: COMPLETED
Conditions: Mental Illness|Schizophrenia|Depression|PTSD|Bipolar Disorder
Interventions: BEHAVIORAL: Cognitive Remediation|BEHAVIORAL: Nintendo Brain Age
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FMT Treating Constipation Patients With Depression and/or Anxiety Symptoms - Clinical Efficacy and Potential Mechanisms
Status: UNKNOWN
Conditions: Constipation - Functional|Depressive Symptoms|Anxiety Symptoms|Gut-Brain Disorders
Interventions: OTHER: FMT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anesthesia and Acute Kidney Injury After Nephrectomy
Status: RECRUITING
Conditions: Nephrectomy
Interventions: DRUG: Propofol|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Knee Arthroplasty
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis|Knee Arthritis|Knee Disease|Knee Pain Chronic
Interventions: DRUG: 0.9% Sodium Chloride Injection|DRUG: Dexamethasone|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anxiety and Fear of Cancer Before and After Banding Without Resection in Small SET Management (QUALI-BANDING-SET)
Status: SUSPENDED
Conditions: Gastrointestinal Subepithelial Tumors
Interventions: OTHER: Initial Anxiety and Fear of Cancer Test|PROCEDURE: Endoscopic band ligation without resection of the subpetihelial tumour.|OTHER: 1-2 Months Anxiety and Fear of Cancer Test|OTHER: 1 Year Anxiety and Fear of Cancer Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess Multiple Ascending Dose, Drug-Drug Interaction, and Asian Pharmacokinetic Study of ABBV-1088
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteer
Interventions: DRUG: ABBV-1088|DRUG: Placebo for ABBV-1088|DRUG: Itraconazole (ITZ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: First in Human Study to Investigate the Safety and Tolerability, Pharmacokinetics, Itraconazole Drug-drug-interaction and Food Effect of BAY1817080
Status: COMPLETED
Conditions: Clinical Trials, Phase I as Topic
Interventions: DRUG: BAY1817080|DRUG: Placebo|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: NET Device for Treating Opioid Use Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid Use Disorder
Interventions: DEVICE: NET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DAREONᵀᴹ-8: A Study to Test How Well Different Doses of BI 764532 in Addition to Standard of Care Are Tolerated by People With Advanced Small Cell Lung Cancer
Status: RECRUITING
Conditions: Small Cell Lung Carcinoma (SCLC)
Interventions: DRUG: BI 764532|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Atezolizumab|DRUG: Durvalumab|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gut Microbiome Changes Following Liraglutide Treatment in Obese Subjects or Overweight Subjects With Co-morbidities
Status: UNKNOWN
Conditions: Obesity
Interventions: DRUG: Liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Ranging Study of the Effect of Ruxolitinib Phosphate Cream When Applied to Participants With Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: OTHER: Placebo Cream|DRUG: Ruxolitinib Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Folfirinox and Stereotactic Body Radiation Therapy for Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer Non-resectable
Interventions: DRUG: Folfirinox|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Adult Stem Cells to Treat Patients With Severe Leg Artery Disease
Status: TERMINATED
Conditions: Critical Limb Ischemia|Arterial Occlusive Disease|Vascular Diseases
Interventions: BIOLOGICAL: autologous CD133+ cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Phototherapy of Barrett's Esophagus
Status: COMPLETED
Conditions: Barrett's Esophagus|High Grade Dysplasia
Interventions: PROCEDURE: Photodynamic therapy|PROCEDURE: radiofrequency ablation of barrett's esophagus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Individualized rTMS in DOC Patients
Status: RECRUITING
Conditions: Disorder of Consciousness|Transcranial Magnetic Stimulation
Interventions: DEVICE: individualized repetitive transcranial magnetic stimulation|DEVICE: Sham repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function
Status: RECRUITING
Conditions: Left Ventricular Dysfunction|Coronary Artery Disease
Interventions: DEVICE: Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®|DEVICE: IABP Intra-aortic balloon pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interactive Effects of an Isocaloric High-protein Diet and Resistance Exercise in Untrained Overweight Young Men
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: BEHAVIORAL: High protein diet, Resistance exercise|BEHAVIORAL: Standard diet, Resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Rotator Cuff Repair With "InSpace" VS Without "InSpace"
Status: RECRUITING
Conditions: Repair of a Cuff Tear
Interventions: DEVICE: repair of a cuff tear|DEVICE: repair of a cuff tear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Motor Imagery Training on Gait and Brain Activation Pattern of Individuals With Parkinson's Disease
Status: UNKNOWN
Conditions: Primary Parkinsonism|Rehabilitation|Kinematics|Gait Disorders, Neurologic
Interventions: OTHER: Mental and Physical Practice|OTHER: Physical Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improve the Survival Rate of Chinese Children and Adolescents With Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Childhood Non-Hodgkin's Lymphoma
Interventions: OTHER: Modified BFM-90 protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Changes in Pain, Disease Activity, and Ultrasound Evidence of Inflammatory Synovitis in Patients Receiving JAK-inhibitor vs. TNF-inhibitor Therapy for Active Rheumatoid Arthritis: A Feasibility Study.
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Upadacitinib|DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Intraocular Pressure Using Simbrinza™ in Patients With Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Brinzolamide 1%/Brimonidine 0.2% ophthalmic suspension|DRUG: Timolol Maleate 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Niacin on Intramyocellular Fatty Acid Trafficking in Upper Body Obesity and Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Obesity
Interventions: DRUG: Niacin|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Racial Differences in Circadian and Sleep Mechanisms for Nicotine Dependence, Craving, and Withdrawal
Status: RECRUITING
Conditions: Smoking|Sleep Disturbance|Nicotine Dependence
Interventions: BEHAVIORAL: Sleep restriction condition|BEHAVIORAL: Sleep extension condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryotherapy Versus Steroids In Alopecia Areata:Trichoscopic Evaluation
Status: UNKNOWN
Conditions: Alopecia Areata
Interventions: PROCEDURE: Cryotherapy|DRUG: Triamcinolone acetonide injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measuring Quality of Life of Versacryl Relined Dentures
Status: UNKNOWN
Conditions: Denture Liners
Interventions: OTHER: Versacryl soft liner|OTHER: Silicone-based soft liner
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Fibrate and a Statin on Endothelial Dysfunction
Status: TERMINATED
Conditions: Diabetes Mellitus|Metabolic Syndrome
Interventions: DRUG: Fenofibrate|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Peptide Receptor Radionuclide Therapy With 177Lu-Dotatate Associated With Metronomic Capecitabine In Patients Affected By Aggressive Gastro-Etero-Pancreatic Neuroendocrine Tumors
Status: UNKNOWN
Conditions: Neuroendocrine Tumors|Gastro Entero Pancreatic Neuroendocrine Tumors
Interventions: DRUG: 28 GBq 177Lu-DOTATATE|DRUG: 22 GBq 177Lu-DOTATATE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pressure Release Versus Thoracic Manipulation in Rhomboids MPS
Status: NOT_YET_RECRUITING
Conditions: Myofascial Pain Syndrome|Trigger Point Pain, Myofascial
Interventions: DEVICE: conventional therapy|OTHER: Experimental group 1 : pressure release technique|OTHER: Experimental group 2: thoracic spine manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Belgian Real Life Non-interventional Study (NIS) in Patients Treated With Xarelto Following an Acute Deep Vein Thrombosis (DVT)
Status: COMPLETED
Conditions: Venous Thrombosis
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Tolerability of Toremifene or Tamoxifen Therapy in Premenopausal Estrogen and Progesterone Receptor Positive Breast Cancer Patients
Status: UNKNOWN
Conditions: Breast Cancer Patients in Premenopausal|Estrogen and/or Progesterone Receptor Positive
Interventions: DRUG: toremifene or tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Supracrestal Tissue Attachment Dimension on Outcome of Scaling and Root Planing and Open Flap Debridement Procedure in Different Periodontal Phenotypes
Status: RECRUITING
Conditions: Periodontitis
Interventions: PROCEDURE: Scaling and root planing and open flap debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Combination Nivolumab and Ipilimumab Retreatment in Patients With Advanced Renal Cell Carcinoma
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Twenty-Four Hour Combined Multi-Channel Impedance and pH Ambulatory Monitoring: Impedance Reflux Episodes of Patients On and Off Proton Pump Inhibitor Therapy
Status: COMPLETED
Conditions: GERD
Interventions: DRUG: Esomeprazole|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Efficacy and Safety of Mirabegron Compared to Solifenacin in Patients With Overactive Bladder Who Were Previously Treated With Another Medicine But Were Not Satisfied With That Treatment.
Status: COMPLETED
Conditions: Urologic Diseases|Urinary Bladder, Overactive|Urinary Bladder Diseases
Interventions: DRUG: Mirabegron|DRUG: Solifenacin succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer
Status: RECRUITING
Conditions: Colonic Neoplasms|Neoplasms, Colon
Interventions: BIOLOGICAL: Dostarlimab|DRUG: CAPEOX|DRUG: FOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Speech Therapy in Trans Women.
Status: COMPLETED
Conditions: Transgenderism|Gender Dysphoria|Speech Therapy|Voice Disorder Due to Transsexualism
Interventions: BEHAVIORAL: Pitch Elevation Therapy|BEHAVIORAL: Articulation Resonance Therapy|BEHAVIORAL: Sham therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of Induction Chemotherapy With ND-420, Cisplatin and Fluorouracil Followed by Surgery in the Treatment of Patients With Localized Squamous Cell Carcinoma of the Esophagus
Status: TERMINATED
Conditions: Localized Squamous Cell Carcinoma of the Esophagus
Interventions: DRUG: ND-420|PROCEDURE: Surgery|DRUG: Cisplatin|DRUG: fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization Strategy of Carotid Artery Stenosis
Status: RECRUITING
Conditions: Carotid Artery Stenosis
Interventions: PROCEDURE: Carotid revascularization|DIAGNOSTIC_TEST: MRI-PWI|DIAGNOSTIC_TEST: CTA|DIAGNOSTIC_TEST: PET/MRI|DIAGNOSTIC_TEST: Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of L-arginine and L-citrulline Supplementation on Muscle Respiration
Status: COMPLETED
Conditions: Dietary Exposure
Interventions: DIETARY_SUPPLEMENT: Dietary Supplement|BEHAVIORAL: Endurance exercise on a cycle ergometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Sustained Interferon Alfa 2b (INF) Therapy of Relapsing Hepatitis C (HCV) Patients Using InfraDure Biopump
Status: WITHDRAWN
Conditions: Hepatitis C
Interventions: BIOLOGICAL: Subcutan implantation of autologus skin graft after ex-vivo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Green Tea as Antioxidant Agent in Management of Oral Lichen Planus
Status: COMPLETED
Conditions: Oral Lichen Planus
Interventions: DRUG: green tea tablets (Green tea extract 5:1) 200 mg|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Brief Intervention to Improve Medication Knowledge and Adherence Among Family Medicine Patients in South Texas
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Hyperlipidemia|Hypertension
Interventions: BEHAVIORAL: Physician counseling for health behavior change
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Epidural Analgesia (EDA) Versus Patient Controlled Analgesia (PCA) in Laparoscopic Colon Surgery
Status: COMPLETED
Conditions: Laparoscopic Colectomy
Interventions: PROCEDURE: Epidural analgesia|PROCEDURE: Patient controlled analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of the Safety and Efficacy of K-604 for the Treatment of Atherosclerosis
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DRUG: K-604|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Cardioprotection and Humoral Mechanism of Limb Ischemia Preconditioning
Status: COMPLETED
Conditions: Ischemic Preconditioning
Interventions: PROCEDURE: limb ischemia preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Inflammatory Cells Activity in Patients With Persistent Asthma Treated With Montelukast (0476-403)(COMPLETED)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: montelukast sodium|DRUG: Comparator: placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Implanted Electrodes Following Regenerative Peripheral Nerve Surgery for Improving Prosthetic Limb Control Signals
Status: RECRUITING
Conditions: Amputation Neuroma|Amputation
Interventions: DEVICE: a bipolar percutaneous intramuscular electromyography electrode
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: CO2 Versus Air Insufflation for Single-balloon Enteroscopy
Status: COMPLETED
Conditions: Intubation Depth
Interventions: DEVICE: CO2 insufflation regulator|DEVICE: Air insufflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Cytokine Persistence as a Marker of Inflammation in the at Risk, Low Socioeconomic Status Pediatric Population
Status: COMPLETED
Conditions: Obstructive Sleep Apnea of Child
Interventions: DIAGNOSTIC_TEST: Cytokine from blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study in Primary Care Evaluating Inclisiran Delivery Implementation + Enhanced Support
Status: COMPLETED
Conditions: Atherosclerotic Cardiovascular Disease|Atherosclerotic Cardiovascular Disease Risk Equivelents|Elevated Low Density Lipoprotein Cholesterol
Interventions: DRUG: Inclisiran|BEHAVIORAL: Behavioural Support|DRUG: Background lipid lowering therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Randomized Controlled Trial of iTAB Plus Motivational Interviewing for PrEP Adherence in Transgender Individuals
Status: COMPLETED
Conditions: Patient Adherence|HIV Seronegativity
Interventions: BEHAVIORAL: brief Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Vardenafil in Patients Suffering From Erectile Dysfunction and Metabolic Syndrome
Status: COMPLETED
Conditions: Erectile Dysfunction|Metabolic Syndrome
Interventions: DRUG: Vardenafil (Levitra, BAY38-9456)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Methylphenidate on Cognitive Abilities of Adults With Bipolar Disorder
Status: UNKNOWN
Conditions: BD
Interventions: DRUG: MPH|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Venetoclax in Combination With Azacitidine (VEN/AZA) Followed by Donor Lymphocyte Infusion (DLI) for Patients With Very High-Risk Acute Myeloid Leukemia (AML) Undergoing Allogeneic Hematopoietic Cell Transplant (HCT)
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Venetoclax|DRUG: Azacitidine|BIOLOGICAL: Donor Lymphocyte Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Impact on Intestinal Sulfate Metabolism
Status: COMPLETED
Conditions: Healthy Nutrition
Interventions: BEHAVIORAL: Plant-Based Diet then animal-based diet|BEHAVIORAL: Animal-based diet then plant-based diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Color Masking Potential of Bioactive and ICON Materials
Status: RECRUITING
Conditions: White Spot Lesion of Tooth
Interventions: DRUG: Icon Infiltrant|DRUG: Bioactive infiltrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Cadonilimab Plus Anlotinib in Advanced STS That Failed the Previous First-line Standard Treatment
Status: RECRUITING
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Candonilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy Against Candida Spp. in Complete Denture Wearers
Status: COMPLETED
Conditions: Photochemotherapy Reaction
Interventions: PROCEDURE: Photodynamic Therapy|DRUG: Nystatin 100.000 units
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigation of Delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD) in Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: GW-1000-02|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Negative Reactions in First Time Blood Donors to Encourage Subsequent Blood Donations
Status: COMPLETED
Conditions: Syncope, Vasovagal
Interventions: BEHAVIORAL: Pre-Donation Water Consumption|BEHAVIORAL: Muscle Tensing Exercise During Donation|BEHAVIORAL: Muscle Tensing Exercise Prior to Donation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hyperpolarized Carbon C 13 Pyruvate Magnetic Resonance Spectroscopic Imaging in Predicting Treatment Response in Patients With Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Adenocarcinoma|PSA Level Greater Than Ten|Stage IIB Prostate Cancer AJCC v8|Stage III Prostate Cancer AJCC v8|Stage IIIA Prostate Cancer AJCC v8|Stage IIIB Prostate Cancer AJCC v8|Stage IIIC Prostate Cancer AJCC v8|Stage IV Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: DRUG: Hyperpolarized Carbon C 13 Pyruvate|PROCEDURE: Magnetic Resonance Spectroscopic Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Travoprost 0.004%/Timolol 0.5% Ophthalmic Solution|DRUG: Latanoprost 0.005% Ophthalmic Solution (XALATAN)|DRUG: Timolol 0.5% Ophthalmic Solution|OTHER: Timolol Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Autonomous Hyperparathyroidism in Post Renal Transplant Recipients
Status: COMPLETED
Conditions: Chronic Allograft Nephropathy|Chronic Kidney Disease|Chronic Renal Failure|Disordered Mineral Metabolism|End Stage Renal Disease|Hyperparathyroidism|Hypophosphatemia|Kidney Disease|Kidney Transplantation|Post Renal Transplantation
Interventions: DRUG: Cinacalcet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Beclomethasone Upper the Endotracheal Cuff on the Occurrence of Sore Throat at Extubation
Status: WITHDRAWN
Conditions: Anesthesia, Endotracheal
Interventions: DRUG: Beclomethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Copper Impact on Venous Insufficiency and Lipodermatosclerosis
Status: COMPLETED
Conditions: Lipodermatosclerosis|Chronic Venous Insufficiency|Venous Insufficiency|Varicose Veins
Interventions: OTHER: Copper impregnated compression stocking|OTHER: Normal compression stocking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A New Oral Treatment For Type II Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: DEN 2.5 mg|DRUG: DEN 7.5 mg|DRUG: DEN 15 mg|DRUG: DEN 30 mg|DRUG: DEN 45 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Modified Widman Flap vs Fibre Retention Osseous Resective Surgery
Status: RECRUITING
Conditions: Periodontitis|Periodontal Pocket|Periodontal Attachment Loss
Interventions: PROCEDURE: Modified Widman Flap (MWF)|PROCEDURE: Fiber Retention Osseous Resective Surgery (FibReORS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pitavastatin on Lipid Profiles in HIV-infected Patients With Dyslipidemia and Receiving Atazanavir/Ritonavir
Status: COMPLETED
Conditions: HIV|Dyslipidemia
Interventions: DRUG: pitavastatin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT