pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Treatment of Diabetic Macular Edema With Aflibercept and Micropulse Laser
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: COMBINATION_PRODUCT: Micropulse Laser|DEVICE: Sham Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Techniques of Crestal Sinus Lift
Status: COMPLETED
Conditions: Crestal Sinus Lift
Interventions: PROCEDURE: crestal sinus lift using ballon technique|PROCEDURE: crestal sinus lift using densah burs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TReatment of Atrial Fibrillation With Dual dEfibrillator in Heart Failure Patients
Status: COMPLETED
Conditions: Heart Failure, Congestive
Interventions: DEVICE: Dual (atrial and ventricular) implantable defibrillator|DEVICE: Dual (atrial and ventricular) implantable defibrillator|DEVICE: Dual (atrial and ventricular) implantable defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MOWI Research Pilot
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Develop & Refine MOWI w/o Amulet|BEHAVIORAL: MOWI Weight Loss Maintenance|BEHAVIORAL: Develop & Refine MOWI w Fitbit|DIETARY_SUPPLEMENT: Develop & Refine MOWI w Fitbit/Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Multi-centre Study Comparing the Polyp Detection Rate of Two Different Types of Bowel Preparation: a 2-litre Solution (MOVIPREP®) Versus a Hyperosmotic and Stimulant Combined Low Volume Bowel Preparation (Sodium Picosulfate and Magnesium Citrate)
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: MOVIPREP|DRUG: CitraFleet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Nocardia Rubra Cell Wall Skeleton (N-CWS) Plus HAIC, Lenvatinib and Tislelizumab in Treating Patients With Advanced HCC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Nocardia rubra cell wall skeleton|PROCEDURE: Hepatic arterial infusion chemotherapy|DRUG: Lenvatinib|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CenteringParenting Clinical Intervention on Kindergarten Readiness in Early Childhood
Status: RECRUITING
Conditions: Parent-Child Relations|Parenting|Child Development|Child Behavior
Interventions: BEHAVIORAL: CenteringParenting Intervention|BEHAVIORAL: Routine Well Child Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Al18F-PSMA-617 and 68Ga-PSMA-617 PET/CT Imaging in the Same Group of Prostate Cancer Patients
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Al18F-PSMA-617|DRUG: 68Ga-PSMA-617
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Invert-Prospective Phase II Randomized Trial of Involved Nodal Versus Elective Neck RadioTherapy
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Cancer
Interventions: DRUG: ENI using IMRT with or without chemotherapy|RADIATION: INRT|RADIATION: ENI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of Epidermolysis Bullosa (Phase III)
Status: RECRUITING
Conditions: Epidermolysis Bullosa
Interventions: DRUG: allo-APZ2-OTS|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intranasal Insulin and Post-stroke Cognition: A Pilot Study
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Intranasal Insulin|DRUG: Intranasal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lurasidone HCL - A 6-week Phase 3 Study of Patients With Acute Schizophrenia.
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Lurasidone|DRUG: Lurasidone|DRUG: Quetiapine XR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A RCT of Compound Lidocaine Cream to Prevent Postoperative Agitation in Patients With Endotracheal Intubation for GA
Status: UNKNOWN
Conditions: Postoperative Agitation of Patients
Interventions: DRUG: Compound Lidocaine Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Growth Hormone and IGF-1 on Anabolic Signals and Stem Cell Recruitment in Human Skeletal Muscle
Status: UNKNOWN
Conditions: Growth Hormone Deficiency|Growth Hormone Treatment
Interventions: DRUG: Genotropin miniquick 0.5 mg, injection
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Dapagliflozin on the Incretin Sensitivity of the Pancreatic Beta Cell
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Macrolide and Glucocorticoid in the Treatment of Chronic Rhinosinusitis After Endoscopic Sinus Surgery
Status: COMPLETED
Conditions: Chronic Rhinosinusitis|Endoscopic Sinus Surgery
Interventions: DRUG: Clarithromycin|DRUG: Glucocorticoid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Everolimus in Treating Patients With Previously Treated Unresectable or Metastatic Esophageal Cancer or Stomach Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: everolimus|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Pembrolizumab Combined With Pemetrexed or Abemaciclib for High Grade Glioma
Status: WITHDRAWN
Conditions: High Grade Glioma
Interventions: DRUG: Pembrolizumab|DRUG: Pemetrexed|DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetics (PKs) of ZYDPLA1 Following Oral Administration in Healthy Volunteers
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: ZYDPLA1 tablet|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Cognitive, Academic and Psychosocial Functioning in Long-Term Survivors of Pediatric Stem Cell Transplantation
Status: COMPLETED
Conditions: Stem Cell Transplant During Childhood|Allogeneic Bone Marrow Transplant During Childhood
Interventions: OTHER: Questionnaire|OTHER: Neurocognitive Evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Riluzole in the Treatment of Spasticity in the Traumatic Chronic Spinal Cord Injury Condition
Status: RECRUITING
Conditions: Spinal Cord Injury
Interventions: DRUG: Riluzole|DRUG: Placebo|BIOLOGICAL: Blood Samples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minocycline for Reduction of Radiation Therapy Treatment-Related Symptom Burden in Oropharynx Cancer: A Randomized Study.
Status: COMPLETED
Conditions: Oropharynx Cancer
Interventions: DRUG: Minocycline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Integrated Management of Chronic Respiratory Diseases
Status: RECRUITING
Conditions: Sleep Apnea, Obstructive|Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Connected actimeter to measure physical activity in OSA patients|DEVICE: Connected BORA Band to measure physical activity in COPD patients only|OTHER: IPAQ to evaluated physical activity|DEVICE: Connected scale to measure weight|DEVICE: Connected tensiometer to measure arterial pressure|DEVICE: Connected BORA Band to measure oxygen saturation in COPD patients only|DEVICE: Connected BORA Band to measure heart rate in COPD patients only|DEVICE: Connected BORA Band to measure respiratory rate in COPD patients only|OTHER: EXASCORE to evaluated COPD severity|OTHER: Epworth scale to evaluate sleepiness|OTHER: Pichot scale to evaluate fatigue|OTHER: Usability questionnaire|OTHER: SF36 questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Shoulder Mobilization Following Supra Scapular Nerve Block in Adhesive Capsulitis
Status: COMPLETED
Conditions: Adhesive Capsulitis
Interventions: OTHER: Shoulder mobilization Group|OTHER: Conventional Treatment Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: AZD8529 Multiple Ascending Dose Study in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: AZD8529|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Repeated Dose IV Baclofen Safety/Bioequivalence Study
Status: UNKNOWN
Conditions: Intravenous Baclofen
Interventions: DRUG: IV Baclofen|DRUG: Oral Baclofen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperthermic Intraperitoneal Oxaliplatin for Peritoneal Malignancies
Status: COMPLETED
Conditions: Peritoneal Cavity Cancer
Interventions: DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin|PROCEDURE: cytoreductive surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Trial of Febuxostat in Korea Gout Patients
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: Febuxostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Japanese Study of BMS-901608 (Elotuzumab) in Combination With Lenalidomide and Low Dose Dexamethasone
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: BMS-901608 (Elotuzumab) 10 mg|BIOLOGICAL: BMS-901608 (Elotuzumab) 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Febuxostat Effect on Blood Pressure in Patients With High Normal Blood Pressure
Status: COMPLETED
Conditions: Prehypertension|Gout|Pulse Wave Velocity|Hypertension|24 Hour Blood Pressure
Interventions: DRUG: Febuxostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A 3-period Crossover Study With GSK573719 as Monotherapy in Adult Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: GSK573719 Active treatment or Placebo|PROCEDURE: GSK573719 (Sub-group cohort)|DRUG: Salbutamol/Albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PTT-936 Alone or in Combination in Patients With Locally Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Locally Advanced or Metastatic Solid Tumors
Interventions: DRUG: PTT-936|DRUG: Combination of PTT-936 and anti-PD-1/L1 therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study To Investigate Patient Preference On Dosing In Ibandronate And Risedronate In Korean Women With Postmenopausal Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: Ibandronate (SB743830HD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ELB245 for 12 Weeks Versus 4mg Tolterodine in Patients With Incontinent Overactive Bladder (OAB)
Status: TERMINATED
Conditions: Overactive Bladder|Urinary Incontinence
Interventions: DRUG: ELB245|DRUG: Tolterodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Neurolinguistic Programming, Progressive Muscle Relaxation Exercises, and Breastfeeding
Status: RECRUITING
Conditions: NEUROLINGUISTIC PROGRAMMING|PROGRESSIVE MUSCLE RELAXATION EXERCISES|CAESAREAN SECTION
Interventions: OTHER: NEURO LINGUISTIC PROGRAM|OTHER: PROGRESSIVE MUSCLE RELAXATION EXERCISES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of Efficacy, Safety, and Tolerability of LNA043 in Patients With Knee Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis
Interventions: DRUG: LNA043 Dosing Regimen A|DRUG: LNA043 Dosing Regimen B|DRUG: LNA043 Dosing Regimen C|DRUG: LNA043 Dosing Regimen D|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Malignant Solid Neoplasm
Interventions: DRUG: Olanzapine|DRUG: Placebo Administration|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pessary Use for Stress Urinary Incontinence in Pregnancy
Status: UNKNOWN
Conditions: Stress Urinary Incontinence|Pregnancy Related
Interventions: DEVICE: Cooper Surgical Ring Pessary with Incontinence Knob
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: rTMS for the Treatment of Freezing of Gait in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DEVICE: High-frequency rTMS|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of GSK561679 in Women With Post-Traumatic Stress Disorder
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: DRUG: GSK561679|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prevalence of Spontaneous Pneumothorax in BHD
Status: UNKNOWN
Conditions: Spontaneous Pneumothorax
Interventions: RADIATION: CT scan of the thorax|GENETIC: blood sample for FLCN mutation analyses
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study of Difluprednate in the Treatment of Inflammation Following Ocular Surgery (ST-601A-002b)
Status: COMPLETED
Conditions: Inflammation
Interventions: DRUG: Difluprednate|DRUG: Difluprednate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Maternal Microcirculation & SDF Imaging
Status: COMPLETED
Conditions: Pregnancy
Interventions: DEVICE: Initial MicroScan® (Microvision Medical) SDF Measurement|DRUG: Spinal Anesthesia- Bupivacaine|DEVICE: Comparative MicroScan® (Microvision Medical) SDF Measurement|DRUG: Bolus Phenylephrine/Ephedrine Treatment|DRUG: Phenylephrine Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nilotinib in Patients With Relapsed or Metastatic Pigmented Villonodular Synovitis/Tenosynovial Giant Cell Tumor/Diffuse-Type Giant Cell Tumor
Status: ACTIVE_NOT_RECRUITING
Conditions: Pigmented Villonodular Synovitis|Diffuse-type Giant Cell Tumor|Tenosynovial Giant Cell Tumor
Interventions: DRUG: nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Near-infrared Light (NIR) Therapy for Diabetic Macular Edema: A Pilot Study
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DEVICE: Warp 10 LED Device|DEVICE: Near-infrared light (NIR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SS1(dsFV)PE38 Plus Pemetrexed and Cisplatin to Treat Malignant Pleural Mesothelioma
Status: TERMINATED
Conditions: Mesothelioma
Interventions: BIOLOGICAL: Multicycle SS1P|DRUG: Pemetrexed|DRUG: Cisplatin|BIOLOGICAL: Single cycle SS1P
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FYS Study: Epidemiological, Multicentre, Cross-sectional Study in a Clinical Practice Environment, About the Relationship Between Functioning Status and the Quality of Sleep Perceived by Schizophrenic Outpatients in Spain
Status: COMPLETED
Conditions: Schizophrenia
Interventions: OTHER: Functioning assessment|OTHER: Quality of sleep assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Infection Rates for the Codman BACTISEAL TM External Ventricular Drainage (EVD) System
Status: COMPLETED
Conditions: Intraventricular Hemorrhage|Subarachnoid Hemorrhage
Interventions: DEVICE: Bactiseal TM EVD|DEVICE: Standard EVD Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measuring Fluid Flow in the Brain Using Alcohol and MRI in Healthy Participants
Status: NOT_YET_RECRUITING
Conditions: Diagnostic Technics, Neurological
Interventions: DIAGNOSTIC_TEST: Single-voxel MRS|DIAGNOSTIC_TEST: Multi-voxel MRSI|DIAGNOSTIC_TEST: Magnetization Transfer Imaging|OTHER: Alcohol ingestion|DEVICE: ClearMate|DIAGNOSTIC_TEST: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Acyclovir in Suppressing HIV Viral Load in Women Coinfected With HIV and Herpes Simplex Virus Type 2 (HSV-2)
Status: COMPLETED
Conditions: HIV Infections|Herpesvirus 2, Human
Interventions: DRUG: Acyclovir|DRUG: Acyclovir placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Thalidomide and Procarbazine in Treating Patients With Recurrent or Progressive Malignant Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: procarbazine hydrochloride|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cycle Ergometer With Biofeedback on Deep Sensation in Elderly Patients With Knee Osteoarthritis
Status: RECRUITING
Conditions: Knee Osteoarthritis|Sensation Disorders
Interventions: OTHER: Cycle Ergometer|DEVICE: Transcutaneous electrical nerve stimulation|DEVICE: Ultrasound|OTHER: Isometric exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Perioperative Portal Vein Pulsatility as a Postoperative Prognostic Indicator in Pulmonary Endarterectomy
Status: UNKNOWN
Conditions: Pulmonary Hypertension|Thromboembolism, Pulmonary|Perioperative/Postoperative Complications|Venous Hypertension|Cardiac Failure
Interventions: OTHER: All patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Evaluation of Muscle miRNA as Biomarkers in Dystrophinopathies
Status: UNKNOWN
Conditions: Muscular Dystrophies|Becker Muscular Dystrophy|Duchenne Muscular Dystrophy
Interventions: OTHER: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Combined Measles-mumps-rubella (MMR) Vaccine in Children in Their Second Year of Life
Status: COMPLETED
Conditions: Measles|Mumps|Rubella|Measles-Mumps-Rubella Vaccine
Interventions: BIOLOGICAL: Priorix|BIOLOGICAL: M-M-R II|BIOLOGICAL: Varivax|BIOLOGICAL: Havrix|BIOLOGICAL: Prevnar 13
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Elongation Longitudinaux Avec Decoaption Osteo-Articulaire (ELDOA) in Cervical Disc Protrusion
Status: COMPLETED
Conditions: Cervical Disc Herniation
Interventions: OTHER: Conservative physical therapy|OTHER: ELDOA stretching exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Fibrin+1.2% Atorvastatin in Treatment of Mandibular Degree II Furcation Defects
Status: COMPLETED
Conditions: Furcation Defects
Interventions: PROCEDURE: Open flap debridement (OFD)|PROCEDURE: OFD with Platelet rich fibrin (PRF)|PROCEDURE: OFD with Platelet rich fibrin (PRF)+1.2% Atorvastatin (Drug) in gel form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Enteric-coated Mycophenolate Sodium (EC-MPS) With Steroid Withdrawal vs EC-MPS With Standard Steroid Regimen in de Novo Renal Transplant Recipients.
Status: COMPLETED
Conditions: Kidney de Novo Transplant
Interventions: DRUG: Enteric-coated Mycophenolate sodium (EC-MPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Darbepoetin Alfa and Anemia of Cancer
Status: TERMINATED
Conditions: Anemia|Anemia of Cancer|Cancer|Carcinoma|Neoplasms|Non-Myeloid Malignancies
Interventions: BIOLOGICAL: darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Telehealth Education for Asthma Connecting Hospital and Home
Status: COMPLETED
Conditions: Asthma in Children
Interventions: BEHAVIORAL: Telehealth Education for Asthma Connecting Hospital and Home|BEHAVIORAL: Standard Care (SC) Comparison Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Tisagenlecleucel in Adult Patients With Aggressive B-cell Non-Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Hodgkin Lymphoma
Interventions: DRUG: Tisagenlecleucel after optional bridging and lymphodepleting chemotherapy|DRUG: Platinum-based immunochemotherapy followed in responding patients with high dose chemotherapy and autologous hematopoietic stem cell transplant (HSCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PANS - A Detailed Study of the Patients, Their Symptoms, Biomarkers and Treatment Offered in a Scandinavian Cohort
Status: COMPLETED
Conditions: Obsessive-compulsive Disorder With Acute Onset|PANDAS|Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections|Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)|Childhood Acute Neuropsychiatric Symptoms (CANS)|Obsessive-compulsive Disorder
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nivolumab and Plinabulin in Treating Patients With Stage IIIB-IV, Recurrent, or Metastatic Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: ALK Gene Translocation|EGFR Activating Mutation|Recurrent Non-Small Cell Lung Carcinoma|ROS1 Gene Translocation|Stage IIIB Non-Small Cell Lung Cancer AJCC v7|Stage IV Non-Small Cell Lung Cancer AJCC v7
Interventions: BIOLOGICAL: Nivolumab|DRUG: Plinabulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene-Modified T Cells, Vaccine Therapy, and Nivolumab in Treating Patients With Stage IV or Locally Advanced Solid Tumors Expressing NY-ESO-1
Status: COMPLETED
Conditions: Adult Solid Neoplasm|Childhood Solid Neoplasm|Metastatic Neoplasm
Interventions: BIOLOGICAL: Aldesleukin|DRUG: Cyclophosphamide|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab|BIOLOGICAL: NY-ESO-1 Reactive TCR Retroviral Vector Transduced Autologous PBL|BIOLOGICAL: NY-ESO-1(157-165) Peptide-pulsed Autologous Dendritic Cell Vaccine|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Readily Available Urinary Sodium Analysis in Patients With Acute Decompensated Heart Failure
Status: COMPLETED
Conditions: Acute Decompensated Heart Failure
Interventions: PROCEDURE: Diuretic protocol|PROCEDURE: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Web-based Parenting Intervention for Mothers of Infants At-Risk for Maltreatment (Baby-Net)
Status: COMPLETED
Conditions: Parenting
Interventions: BEHAVIORAL: Baby-Net|BEHAVIORAL: Developmental Awareness Skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3a, Repeat Dose, Open-label, Long-term Safety Study of Mepolizumab in Asthmatic Subjects
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: Mepolizumab|DRUG: SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy, Monoclonal Antibody, and Natural Killer Cells in Treating Young Patients With Recurrent or Refractory Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: Humanized anti-GD2 antibody|DRUG: Chemotherapy|OTHER: Cytokines|BIOLOGICAL: Natural killer cells|DEVICE: CliniMACS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Plyometric Training Isometric Strength Training on Quadriceps Strength and Functional Performance.
Status: COMPLETED
Conditions: Football Players
Interventions: OTHER: Isometric strength training for 8 week|OTHER: Conventional training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Spatiotemporal Dynamics of the Human Emotion Network
Status: ENROLLING_BY_INVITATION
Conditions: Epilepsy|Depression|Anxiety|Emotions
Interventions: BEHAVIORAL: Viewing visual stimuli and electrical stimulation of the brain
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: X-3 Polyethylene Survival Outcomes Study
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee|Total Knee Replacement
Interventions: DEVICE: Stryker X3 Crosslink Polyethylene|DEVICE: N2Vac Polyethylene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Spinal Hydromorphone Versus Morphine for Post-Cesarean Delivery Analgesia
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Spinal Hydromorphone|DRUG: Spinal Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Nasal Fentanyl and Oral Transmucosal Fentanyl (Actiq) in Cancer Breakthrough Pain (FT-019-IM)
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Nasal fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Antiviral Therapy on Host Immune in Patients With Chronic Hepatitis B Virus(HBV) Infection
Status: COMPLETED
Conditions: HBeAg Positive Chronic Hepatitis B Infection
Interventions: DRUG: Telbivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Safety, Tolerability, and Immunogenicity of the Adjuvanted Trivalent Subunit Influenza Vaccine and the Non-Adjuvanted Trivalent Subunit Influenza Vaccine Compared to the Non-Adjuvanted Trivalent Split Influenza Vaccine in Children 6 to < 72 Months of Age
Status: COMPLETED
Conditions: Influenza Disease
Interventions: BIOLOGICAL: Trivalent split influenza vaccine (TIV)|BIOLOGICAL: MF59-adjuvanted trivalent influenza vaccine (aTIV)|BIOLOGICAL: Licensed comparator trivalent split influenza vaccine (comparator TIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Can Targeted Elimination of B-cell Depletion Therapy and/or Combination Therapy on Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: cTACE or DEB-TACE+HAIC Combined With Regorafenib ± Anti-PD1 Antibody for uHCC
Status: UNKNOWN
Conditions: HCC|Transarterial Chemoembolization|Hepatic Arterial Infusion Chemotherapy|Regorafenib
Interventions: DRUG: Regorafenib|DEVICE: cTACE/DEB-TACE-HAIC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Magnesium Nutrition and Sleep Behavior in Older Adults
Status: COMPLETED
Conditions: Nutritional Deficiency|Insomnia
Interventions: DIETARY_SUPPLEMENT: Sugar Pill|DIETARY_SUPPLEMENT: magnesium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Lymphocytic Leukemia Responds to Dermal Chelation
Status: UNKNOWN
Conditions: Chronic Lymphocytic Leukemia
Interventions: DEVICE: Dermal Chelation|DIETARY_SUPPLEMENT: Nutritional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Plasma Rich in Growth Factors (PRGF) in Pilonidal Sinus Excision
Status: COMPLETED
Conditions: Pilonidal Sinus
Interventions: PROCEDURE: sinus pilonidal excision+ PRGF|PROCEDURE: sinus pilonidal excision and standard cares
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Purpose of This Trial is to Determine if Regorafenib Plus Durvalumab (MEDI4736) is Safe and Effective in Treatment of Chemo Refractory Advanced Biliary Tract Cancers
Status: RECRUITING
Conditions: Advanced Biliary Tract Cancer
Interventions: DRUG: Durvalumab|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kineflex Artificial Disc System to Treat Degenerative Disc Disease (DDD)
Status: TERMINATED
Conditions: Degenerative Disc Disease
Interventions: DEVICE: Lumbar Artificial Disc|DEVICE: Charite Artificial Disc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: SAEM: A Serious Game for Emotional Regulation Problems in Adolescents
Status: UNKNOWN
Conditions: Adolescents
Interventions: BEHAVIORAL: Serious Game: Emotional Health Island (SAEM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Short-term Sintilimab in Combination With Taxane and Carboplatin for Neoadjuvant Therapy in Triple-negative Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Triple-negative Breast Cancer
Interventions: DRUG: Taxane and Carboplatin|DRUG: Short-term Sintilimab|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptability/Tolerance of Protein Substitutes in Tablet Form for the Dietary Management of Rare Aminoacidopathies
Status: NOT_YET_RECRUITING
Conditions: Tyrosinemia, Type I|Tyrosinemia, Type II|Tyrosinemia, Type III|Alkaptonuria|Homocystine; Metabolic Disorder|MSUD (Maple Syrup Urine Disease)
Interventions: DIETARY_SUPPLEMENT: Zero minis (range of protein substitutes in tablet form)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: REducing SPEECH-related Side-effects of Deep Brain Stimulation in Parkinson's Disease Via Automated Speech Analysis
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: OTHER: Change of stimulation amplitudes in dopaminergic OFF drug state
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study Evaluating the Safety and Effectiveness of a Nasal Spray to Treat Seasonal Allergies
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: azelastine HCl/fluticasone propionate|DRUG: azelastine Hcl|DRUG: fluticasone propionate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biofeedback to Increase Propulsion During Walking After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: PROCEDURE: Gait Training with Biofeedback|PROCEDURE: Gait Training with Verbal Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimization of Blood Levels of 25(OH)-Vitamin D in African Americans
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DRUG: Vitamin D|DRUG: Placebo|DRUG: Vitamin D + L-cysteine|DRUG: L-cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Immunonutrition on the Patients With Cystic Fibrosis
Status: UNKNOWN
Conditions: Cystic Fibrosis|Malnutrition|Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: Impact-Nutridrink|DIETARY_SUPPLEMENT: Nutridrink-Impact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Opioid Free Anaesthesia in Cardiac Surgery With Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Opioid Free Anaesthesia|Opioid Anaesthesia
Interventions: PROCEDURE: Opioid free anaesthesia|PROCEDURE: Opioid anaesthesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiolabeled Monoclonal Antibody Therapy and High-Dose Chemotherapy Followed By Autologous Peripheral Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: Carmustine|DRUG: cytarabine|DRUG: etoposide|DRUG: melphalan|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: yttrium Y 90 ibritumomab tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First In Human Study for Small to Medium-sized Abdominal Aortic Aneurysm (AAA)
Status: ACTIVE_NOT_RECRUITING
Conditions: Abdominal Aortic Aneurysm|AAA|Dilation Aorta
Interventions: DEVICE: Endovascular Aneurysm Stabilization Treatment (EAST)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Angiotensin-(1-7) Cardiovascular Effects in Aging
Status: RECRUITING
Conditions: Aging
Interventions: DRUG: Angiotensin-(1-7)|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of 24-Hour Intragastric pH Using Esomeprazole, Lansoprazole, and Pantoprazole in Hispanic Patients With GERD
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Esomeprazole 40mg|DRUG: Pantoprazole 40mg|DRUG: Lansoprazole 30mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose TamOxifen and LifestylE Changes for bReast cANcer prevenTion
Status: RECRUITING
Conditions: BRCA Mutation|PALB2 Gene Mutation|Ductal Carcinoma in Situ|Lobular Carcinoma in Situ|ATM Gene Mutation|CHEK2 Gene Mutation|CDH1 Gene Mutation|RAD51C Gene Mutation|RAD51D Gene Mutation
Interventions: DRUG: Tamoxifen 10 mg Tablet|OTHER: Intermittent caloric restriction|BEHAVIORAL: Step counter Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Multiple Doses of Itraconazole on the Multiple Dose Pharmacokinetics of Lu AE58054 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Lu AE58054 30 mg|DRUG: Lu AE58054 30 mg + itraconazole 200 mg|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between hCG and GnRH Agonist for Ovulation Induction in Patients With High Response to IVF Drugs
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: Arvekap, Pregnyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety And Efficacy Of Ziprasidone In Adolescents With Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: placebo|DRUG: Ziprasidone oral capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacodynamic Study With Ticagrelor in African American Patients
Status: COMPLETED
Conditions: Stable Coronary Artery Disease
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness in Chronic Kidney Disease
Status: RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: BEHAVIORAL: Mindfulness-based stress reduction (MBSR)|BEHAVIORAL: Health enhancement program (HEP)|DEVICE: Transcutaneous Vagus Nerve Stimulation (tVNS)|DEVICE: Sham-transcutaneous Vagus Nerve Stimulation (tVNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Beta-only IL-2 ImmunoTherapY Study
Status: RECRUITING
Conditions: Advanced Solid Tumor|Unresectable Solid Tumor|Clear Cell Renal Cell Carcinoma|Triple Negative Breast Cancer|Non-Small Cell Lung Cancer Squamous|Non-Small Cell Lung Cancer Non-squamous|Colorectal Cancer (MSI-H)|Gastric Cancer|Cervical Cancer|Basal Cell Carcinoma|Bladder Cancer|Merkel Cell Carcinoma|Squamous Cell Carcinoma of Head and Neck|Cutaneous Squamous Cell Carcinoma|Pleural Mesothelioma|Esophageal Cancer|Endometrial Carcinoma|Solid Tumor|Solid Tumor, Adult|MSI-H Solid Malignant Tumor|Cancer With A High Tumor Mutational Burden|Epithelial Ovarian Carcinoma|Primary Peritoneal Cancer|Gastroesophageal Junction (GEJ) Cancer|Acral Melanoma|Mucosal Melanoma|Cutaneous Melanoma|DMMR Solid Malignant Tumor|Fallopian Tube Cancer|Ovarian Cancer|MSI-H Cancer|DMMR Cancer|Pancreas Adenocarcinoma (MSI-H)|Skin Cancer
Interventions: DRUG: MDNA11|DRUG: Pembrolizumab (KEYTRUDA®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EPOgen and Restrictive Transfusions in Patients Undergoing Cardiac Surgery (EPORT)
Status: TERMINATED
Conditions: Cardiac Surgery-CABG|Cardiac Valve Replacement
Interventions: DRUG: Epogen|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health Effects of Soccer Training in Men With Prostate Cancer Receiving Androgen Deprivation Therapy
Status: COMPLETED
Conditions: Prostatic Neoplasms|Exercise|Soccer Training|Androgen Deprivation Therapy
Interventions: BEHAVIORAL: Soccer training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oral Nutritional Supplementation of Hemodialysis Patients
Status: COMPLETED
Conditions: Hemodialysis Complication
Interventions: DIETARY_SUPPLEMENT: Fresubin® Protein Energy DRINK|DIETARY_SUPPLEMENT: NEPRO® , Abbott
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Dronabinol and Vaporized Cannabis in Chronic Low Back Pain
Status: COMPLETED
Conditions: Cannabis|Low Back Pain|Neuropathic Pain
Interventions: DRUG: Placebos|DRUG: dronabinol|DRUG: Vaporized Cannabis 3.7% THC/5.6% CBD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Subcutaneously Administered Tocilizumab in Participants With Systemic Juvenile Idiopathic Arthritis
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of JNJ-64565111 in Non-diabetic Severely Obese Participants
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: JNJ-64565111 Dose Level 1|DRUG: JNJ-64565111 Dose Level 2|DRUG: JNJ-64565111 Dose Level 3|DRUG: Liraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of MEDI6570 in Patients With a History of Myocardial Infarction
Status: COMPLETED
Conditions: Coronary Heart Disease (CHD)
Interventions: BIOLOGICAL: MEDI6570|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ischemic Compression With Stretching on Patients With Upper Back Pain
Status: UNKNOWN
Conditions: Myofascial Pain Syndrome
Interventions: OTHER: Ischemic compression with stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vasopressor Therapy on Renal Perfusion in Septic Shock
Status: NOT_YET_RECRUITING
Conditions: Septic Shock|Acute Kidney Injury
Interventions: DRUG: Angiotensin II|DRUG: Vasopressin|DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Multi-site Anesthesia Randomized Controlled STudy of End Tidal Control Compared to Conventional Anesthesia Results
Status: COMPLETED
Conditions: Et Control Performance in Adult Population Surgery
Interventions: DEVICE: Et Control Feature|DEVICE: Conventional Fresh Gas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Evaluation of Neuroma Perfusion With Indocyanine Green Fluorescence Angiography
Status: ENROLLING_BY_INVITATION
Conditions: Neuroma|Neuroma Amputation|Neuroma of Upper Limb|Neuroma of Lower Limb
Interventions: DRUG: Indocyanine green
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laryngopharyngeal Reflux Before and After Cricopharyngeal Myotomy
Status: COMPLETED
Conditions: Laryngopharyngeal Reflux|Zenker's Diverticulum
Interventions: PROCEDURE: Cricopharyngeal myotomy|DIAGNOSTIC_TEST: PH probe Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC