pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Influence of Fluid Intake on Daily Biological Rhythm and Mental Performance in Healthy Young Adults
Status: UNKNOWN
Conditions: Healthy|Habitual; Drinking|Stress, Physiological|Stress, Psychological
Interventions: BEHAVIORAL: Increasing or decreasing daily total fluid intake
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tranexamic Acid in Proximal Humeral Fractures
Status: UNKNOWN
Conditions: Proximal Humeral Fracture|Surgical Treatment
Interventions: DRUG: Tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Assessment of Effectiveness and Safety of L-ESPB Versus Absence of Locoregional Block in Hip Surgery
Status: RECRUITING
Conditions: Hip Fractures|Lumbar Erector Spinae Plane Block
Interventions: DRUG: Lumbar Erector Spinae Plane Block. L bupivacaína 0.25%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Unfractioned Heparin for Treatment of Sepsis Caused by Abdominal Infection
Status: RECRUITING
Conditions: Sepsis|Gram-Negative Bacterial Infections|Heparin
Interventions: DRUG: Unfractionated Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate GSK3052230 in Combination With Paclitaxel and Carboplatin, or Docetaxel or as Single Agent in Subjects With Solid Malignancies and Deregulated Fibroblast Growth Factor (FGF) Pathway Signaling
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: GSK3052230|DRUG: paclitaxel|DRUG: carboplatin|DRUG: docetaxel|DRUG: pemetrexed|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LBH589 and Bevacizumab in Patients With Recurrent High Grade Glioma
Status: COMPLETED
Conditions: Malignant Glioma
Interventions: DRUG: LBH589|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dupilumab in Japanese Patients With Chronic Rhinosinusitis With Nasal Polyp (SINUS-M52)
Status: COMPLETED
Conditions: Chronic Rhinosinusitis With Nasal Polyps
Interventions: DRUG: Dupilumab SAR231893
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fenofibrate for Compensated Cirrhosis Patients With Primary Biliary Cholangitis
Status: RECRUITING
Conditions: Primary Biliary Cholangitis
Interventions: DRUG: Fenofibrate 200mg|DRUG: Placebo|DRUG: UDCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Efficacy of Ramosetron for Treatment of Established PONV After Laparoscopic Surgery
Status: COMPLETED
Conditions: Abdominal Mass
Interventions: DRUG: Ondansetron|DRUG: Ramosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rifaximin for the Treatment of Gastrointestinal Toxicities Related to Pertuzumab-Based Therapy in Patients With Stage I-III HER2 Positive Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|HER2 Positive Breast Carcinoma|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions: OTHER: Best Practice|OTHER: Questionnaire Administration|DRUG: Rifaximin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anchor for Robotic Sacrocolpopexy
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse
Interventions: OTHER: Anchor|OTHER: Suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Tocilizumab + Methotrexate on Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis Currently on Methotrexate Therapy
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Methotrexate|DRUG: Placebo|DRUG: tocilizumab [RoActemra/Actemra]|DRUG: tocilizumab [RoActemra/Actemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Hydrochloride With or Without Vismodegib in Treating Patients With Recurrent or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Pancreas|Recurrent Pancreatic Cancer|Stage IV Pancreatic Cancer
Interventions: DRUG: vismodegib|DRUG: gemcitabine hydrochloride|OTHER: hydrocortisone/placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intermittent Oro-esophageal Tube Feeding on Dysphagic Patients With Parkinson Disease
Status: WITHDRAWN
Conditions: Parkinson Disease
Interventions: DEVICE: Nasogastric tube|DEVICE: Intermittent Oro-esophageal Tube|BEHAVIORAL: Comprehensive rehabilitation training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Epitomee Capsule on Body Weight in Patients With Overweight and Obesity
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: DEVICE: Epitomee Capsule|OTHER: Control-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Assess the Effects of Doxazosin on Polysomnography in PTSD
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: DRUG: Doxazosin XL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Intravitreal Bevacizumab in Pars Plana Vitrectomy for Diabetic Vitreous Hemorrhage
Status: UNKNOWN
Conditions: Recurrent|Hemorrhage
Interventions: PROCEDURE: bevacizumab injection|PROCEDURE: bevacizumab injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Retrospective Cervical Cancer Oligo States (Recurrence, Metastasis) Multicentre Outcomes Study
Status: NOT_YET_RECRUITING
Conditions: Cancer, Cervical|Recurrence|Metastasis
Interventions: OTHER: Concurrent Chemoradiation, Systemic Chemotherapy other locally directed therapies (like surgery, ablation, etc.)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vitamin D and Physical Activity for Prevention of Sarcopenia in Osteoporosis
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DRUG: Vitamin D|OTHER: Physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intervention to Improve Inhalative Adherence
Status: COMPLETED
Conditions: Chronic Asthma|COPD
Interventions: DEVICE: Smartinhaler/POEMS with audio reminders and additional support calls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of 2 Probiotics During Nicotine Replacement Therapy on Withdrawal Symptoms Associated With Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DIETARY_SUPPLEMENT: Probiotic L008-1|DIETARY_SUPPLEMENT: Probiotic L008-2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Reproductive Hormones on Mood and Behavior
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Leuprolide Acetate 3.75|DRUG: Estradiol|DRUG: Progesterone|DRUG: Placebo suppository|DRUG: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: BASIC_SCIENCE
Clinical trial: High Definition Transcranial Alternating Current Stimulation (HD-tACS) for Post-stroke Aphasia
Status: UNKNOWN
Conditions: Transcranial Alternating Current Stimulation|Post-stroke Aphasia|Functional Magnetic Resonance Imaging
Interventions: DEVICE: High definition transcranial alternating current stimulation|DEVICE: sham high definition transcranial alternating current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors
Status: UNKNOWN
Conditions: Brain and Central Nervous System Tumors|Extragonadal Germ Cell Tumor|Ovarian Cancer|Testicular Germ Cell Tumor
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: lenograstim|BIOLOGICAL: pegfilgrastim|DRUG: cisplatin|DRUG: gemcitabine hydrochloride|DRUG: ifosfamide|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Trial of Filanesib in Relapsed/Refractory Multiple Myeloma (AfFIRM)
Status: COMPLETED
Conditions: Advanced Multiple Myeloma
Interventions: DRUG: Filanesib, KSP (Eg5) inhibitor; intravenous|DRUG: Filgrastim, granulocyte-colony stimulating factor (G-CSF); subcutaneous
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib and Venetoclax Treatment of Newly Diagnosed Patients With CLL at High Risk of Infection or Early Treatment
Status: RECRUITING
Conditions: CLL
Interventions: DRUG: Acalabrutinib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Breath Control and Mindfulness for Post Concussion Anxiety and Depression: a Feasibility Study
Status: UNKNOWN
Conditions: Post-Concussion Syndrome|Anxiety Disorders and Symptoms|Depressive Symptoms
Interventions: BEHAVIORAL: Breath Control - Equal Breathing Technique|BEHAVIORAL: Guided Mindfulness Exercise|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CPVI With Modified Linear Ablation Versus CPVI in Patients With Long-standing Persistent Atrial Fibrillation (SINUS)
Status: NOT_YET_RECRUITING
Conditions: Long-standing Persistent Atrial Fibrillation|Ablation
Interventions: PROCEDURE: CPVI-MLA|PROCEDURE: CPVI only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Inhalative Doses of BEA 2180 BR in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BEA 2180 BR|DRUG: Placebo|DEVICE: Respimat®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Ability of Adipose Flap Over the NVB to Improve Sexual and Urinary Function Following Radical Prostatectomy
Status: UNKNOWN
Conditions: Prostate Cancer|Erectile Dysfunction|Urinary Incontinence
Interventions: PROCEDURE: Technical modification during radical prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Complex Eye Movements in Parkinson's Disease and Related Movement Disorders
Status: COMPLETED
Conditions: Parkinson Disease|Parkinson's Disease and Parkinsonism|Progressive Supranuclear Palsy|Corticobasal Degeneration|Parkinsonian Disorders|Essential Tremor|Vascular Parkinsonism|Multiple System Atrophy, Parkinson Variant|Parkinsonian Syndrome|Huntington Disease
Interventions: DIAGNOSTIC_TEST: Complex eye movement exam
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase IIb Study of OligoG in Subjects With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: alginate oligosaccharide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Control of Pain in Intravitreal Injections Using Topical NSAIDs
Status: COMPLETED
Conditions: Intravitreal Injections|IVI
Interventions: DRUG: Bromfenac|DRUG: Artificial tears
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rehabilitation Strategies to Improve Outcomes For Patients With a Lower Extremity Fracture
Status: RECRUITING
Conditions: Femoral Fracture|Tibial Fractures
Interventions: OTHER: Standard of Care Physical Therapy Program|OTHER: Speed Walking Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks.
Status: COMPLETED
Conditions: Port Wine Stain
Interventions: DRUG: Rapamycin Treatment of Port Wine Stain
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety Of Zomig Nasal Spray For Acute Migraine Treatment In Subjects 6 To 11 Years, With OLE
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Placebo ZNS|DRUG: ZNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Technosphere® Insulin Inhalation Powder and Lantus® Compared to Humalog® and Lantus® Over 16-Weeks
Status: TERMINATED
Conditions: Diabetes, Type 1
Interventions: DRUG: Technosphere Insulin|DRUG: Insulin glargine|DRUG: Insulin lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer
Status: RECRUITING
Conditions: Endometrial Cancer|Cervical Cancer|Atypical Endometrial Hyperplasia|Cervical Dysplasia|Adnexal Mass|Ovarian Cancer
Interventions: DIAGNOSTIC_TEST: Tampon Collection|DIAGNOSTIC_TEST: Blood Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Virtual Darkness as Additive Treatment in Mania
Status: COMPLETED
Conditions: Bipolar Disorder|Mania
Interventions: DEVICE: Blue-blocking goggles/screens|DEVICE: Clear-lensed goggles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab, Lenvatinib and Chemotherapy After TKIs in NSCLC
Status: RECRUITING
Conditions: Nsclc|EGFR Activating Mutation|EGF-R Positive Non-Small Cell Lung Cancer|ALK Gene Rearrangement Positive|ROS1 Gene Rearrangement|ROS1 Positive NSCLC - Reactive Oxygen Species 1 Positive Non-Small Cell Lung Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Lenvatinib|DRUG: Pemetrexed|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Viral Immunotherapy in Relapsed/Refractory Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide or Pomalidomide|BIOLOGICAL: REOLYSIN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluorouracil, Epirubicin, and Cyclophosphamide Alone or Followed by Paclitaxel for Early Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: paclitaxel|DRUG: Fluorouracil|DRUG: Epirubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2/3 Study of GLASSIA for the Treatment of Acute GvHD
Status: TERMINATED
Conditions: Graft Versus Host Disease
Interventions: BIOLOGICAL: GLASSIA|DRUG: methylprednisolone or equivalent steroid|BIOLOGICAL: Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study of Two Home Based Muscle Strengthening Programs for Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: High Intensity Interval Training|OTHER: Progressive Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Research About CD70-targeted CAR-NKT Cells Therapy Advanced Malignant Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: COMBINATION_PRODUCT: Cyclophosphamide + Fludarabine + Infusion of CAR-NKT Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Atorvastatin and Pitavastatin on the Effect of HbA1c in AMI Patients With Abnormal Glucose Metabolism
Status: UNKNOWN
Conditions: Acute Myocardial Infarction|Glucose Metabolism Disorders
Interventions: DRUG: Pitavastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes of Premolars Restored With Ceramic Vonlay Restorations Versus Onlay Using Modified USPHS Criteria
Status: UNKNOWN
Conditions: Clinical Performance of Ceramic Vonlays
Interventions: PROCEDURE: Vonlay Ceramic restorations|PROCEDURE: Onlay Ceramic restorations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial on the Effect of Topical Phenytoin on Healing After Fistulotomy
Status: UNKNOWN
Conditions: Anal Fistula
Interventions: DRUG: Phenytoin 2% spray|PROCEDURE: Anal fistulotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Donanemab (LY3002813) Compared With Aducanumab in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 4)
Status: COMPLETED
Conditions: Mild Cognitive Impairment (MCI)|Alzheimer Disease
Interventions: DRUG: Donanemab|DRUG: Aducanumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Examine the Use of Rivaroxaban After Angioplasty for Critical Limb Ischemia
Status: COMPLETED
Conditions: Critical Limb Ischemia
Interventions: DRUG: rivaroxaban plus aspirin|DRUG: clopidogrel plus aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Two Zika Viruses for Use in Controlled Human Infection Models (CHIM)
Status: RECRUITING
Conditions: Zika Virus
Interventions: OTHER: ZIKV-SJRP/2016-184 Strain|OTHER: Experimental: ZIKV-Nicaragua/2016 Strain|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Success Rate of 4 Injection Protocols for Mandibular First Molars With Symptomatic Irreversible Pulpitis
Status: COMPLETED
Conditions: Root Canal Infection
Interventions: PROCEDURE: local anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adductor Canal Block in an Enhanced Recovery Program After Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Total Knee Arthroplasty|Knee Osteoarthritis
Interventions: PROCEDURE: Single adductor canal block|PROCEDURE: Simulated adductor canal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotic Use Bifidobacterium Animalis Subsp. Lactis in Peri-implant Mucositis
Status: COMPLETED
Conditions: Mucositis Oral
Interventions: OTHER: Mechanical debridements|BIOLOGICAL: Bifidobacterium animalis subsp. lactis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Aripiprazole on Patients With Metabolic Syndrome
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Bipolar Disorder|Metabolic Syndrome X
Interventions: DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy vs Hormonal Treatment in Platinum-resistant Ovarian Cancer Resistant or Refractory to Platinum and Taxane
Status: COMPLETED
Conditions: Ovarian Cancer|Peritoneal Cancer|Cancer of the Fallopian Tube
Interventions: DRUG: Tamoxifen|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Study of an Eccentric Training Program and Stretching for Patients With Chronical Rotator Cuff Tendinopathy
Status: COMPLETED
Conditions: Chronical Rotator Cuff Tendinopathy
Interventions: PROCEDURE: Eccentric training program|PROCEDURE: Traditional training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Booster and Catch-up Vaccination With Vaccine GSK1024850A
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Pneumococcal vaccine GSK1024850A|BIOLOGICAL: Pneumococcal vaccine GSK1024850A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase II Study of Pegylated Interferon Alfa-2b for the Adjuvant Treatment of Melanoma Subjects in Russia (MK-4031-400)
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: Pegylated Interferon Alfa-2b|BIOLOGICAL: Pegylated Interferon Alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Oxaliplatin for Hepatocellular Carcinoma With Platelet Counts Greater Than 100,000 Per Microliter
Status: COMPLETED
Conditions: Liver Cancer
Interventions: DRUG: Gemcitabine and Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Ropivacaine and Ropivacaine With Dexmeditomedine in TAP Blocks
Status: COMPLETED
Conditions: Pregnancy
Interventions: DRUG: Ropivacaine + Dexmedetomidine|OTHER: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PINIT Study: Primary Intranasal Insulin Trial
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: intranasal insulin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Laboratory Study of Licensed H1N1 Influenza Vaccines in HIV-1 Perinatally Infected Children and Youth
Status: COMPLETED
Conditions: HIV-1 Infection|H1N1|Influenza|Flu
Interventions: BIOLOGICAL: FluMist|BIOLOGICAL: Fluvirin|BIOLOGICAL: Fluzone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interleukin-1 Blockade in Acute Myocardial Infarction to Prevent Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: DRUG: Anakinra|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Genetic and Environmental Risk Factors of Type 1 Autoimmune Diabetes and Its Early Complications
Status: UNKNOWN
Conditions: Diabetes Mellitus|Insulin-Dependent
Interventions: OTHER: Collect of environmental data on T1D patients before diagnosis|GENETIC: Collect of blood samples for DNA extraction and genetic characterization (GWAS)|OTHER: Collect of clinical data on the disease and its evolution|OTHER: Collect of environmental data on French controls (age-matched for T1D patients)|GENETIC: Collect of blood samples for DNA extraction and genetic characterization (GWAS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Role of Caveolin 1 (CAV-1) Deficiency in Response to Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Treatment
Status: NOT_YET_RECRUITING
Conditions: Overweight and Obesity
Interventions: DIAGNOSTIC_TEST: 24-hour ambulatory blood pressure|DIETARY_SUPPLEMENT: Liberal salt diet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevention of Malaria in HIV-uninfected Pregnant Women and Infants
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Monthly Sulfadoxine-Pyrimethamine (SP) During Pregnancy|DRUG: Monthly Dihydroartemisinin-Piperaquine (DP) During Pregnancy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Everolimus in Combination With Imatinib in Patients With Glivec Refractory/Resistant Gastrointestinal Stromal Tumors
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: RAD001|DRUG: Imatinib 600mg/day (Glevec is the brand name for imatinib)|DRUG: Imatinib 800mg/day (Glevec is the brand name for imatinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Mindfulness During Opioid Tapering for patientS With Chronic Pain (The AMOS Study)
Status: RECRUITING
Conditions: Low Back Pain
Interventions: BEHAVIORAL: Mindfulness-Oriented Recovery Enhancement: (MORE) group|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy&Safety of ALTB-168 in Patients With Moderate to Severe Active,Anti-TNF Alpha and/or Anti-integrin Refractory UC
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: BIOLOGICAL: ALTB-168
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacy-based PrEP Delivery in Kenya
Status: RECRUITING
Conditions: Hiv
Interventions: BEHAVIORAL: Pharmacy PrEP/PEP for a fee|BEHAVIORAL: Pharmacy PrEP/PEP for free|BEHAVIORAL: HTS counselor supported pharmacy PrEP/PEP for free|BEHAVIORAL: Pharmacy referral to clinic-based PrEP/PEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Percutaneous Needle Electrolysis (PNE) on the Concha of the Ear
Status: RECRUITING
Conditions: Headache
Interventions: OTHER: percutaneous needle electrolysis|OTHER: Dry needling|OTHER: Sham needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block Improves Organ Dysfunction in Septic Patients With Acute Gastrointestinal Injury
Status: RECRUITING
Conditions: Sepsis|Acute Gastrointestinal Injury|Organ Dysfunction Syndrome
Interventions: PROCEDURE: Erector spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Microneedling With Topical Vitamin C in Treatment of Acne Scarring
Status: COMPLETED
Conditions: Acne Vulgaris|Acne Scars
Interventions: DEVICE: Dermaroller|DRUG: Topical Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Better Way to Decrease Knee Swelling in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Intermittent Pneumatic Compression|OTHER: Cold-pack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Immunotherapy for NSCLC (ECTOP-1030)
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Atezolizumab|DRUG: Nivolumab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interleukin-2 Plus Bryostatin 1 in Treating Patients With Melanoma or Kidney Cancer
Status: COMPLETED
Conditions: Kidney Cancer|Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|DRUG: bryostatin 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Updated Continuous Glucose Monitoring (CGM) Form Factor in Adults, Adolescents and Pediatrics
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Type 2 Diabetes Mellitus
Interventions: DEVICE: Continuous Glucose Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Weight Gain, Eating Patterns, and Development of Body Composition During Initiation of Basal Insulin Therapy in Patients With Type 2 Diabetes: A Comparison of Insulin Detemir and Insulin Glargine
Status: TERMINATED
Conditions: Diabetes|Obesity
Interventions: DRUG: insulin Levemir|DRUG: insulin Lantus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combined Bipolar Radiofrequency&Pulsed Dye Laser Treatment
Status: COMPLETED
Conditions: Port-Wine Stain
Interventions: DEVICE: Pulsed Dye Laser|DEVICE: Combined Bipolar Radiofrequency&Pulsed Dye Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proteins From Duckweed Trial
Status: COMPLETED
Conditions: Degree of Digestilbility
Interventions: DIETARY_SUPPLEMENT: Duckweed protein|DIETARY_SUPPLEMENT: Whey protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose-Escalation Study of TH-302 in Combination With Sunitinib to Treat Patients With Advanced Renal Cell Carcinoma,Gastrointestinal Stromal Tumors and Pancreatic Neuroendocrine Tumors
Status: UNKNOWN
Conditions: Advanced Renal Cell Carcinoma|Gastrointestinal Stromal Tumors|Pancreatic Neuroendocrine Tumors
Interventions: DRUG: TH-302
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Clarithromycin-based and Furazolidone-based Bismuth-containing Regimens for H. Pylori Eradication
Status: COMPLETED
Conditions: Helicobacter Pylori
Interventions: DRUG: Furazolidone|DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Earliest Stage Treatment of Aktinic Keratosis With Imiquimod 3.75% Cream
Status: COMPLETED
Conditions: Actinic Keratoses
Interventions: DRUG: Imiquimod 3.75% Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulpotomy in Carious Permanent Mature Teeth: Pulp Survival and Risk Factors
Status: COMPLETED
Conditions: Pulpitis|Pulp Exposure, Dental|Pulp and Periapical Tissue Disease
Interventions: PROCEDURE: Pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroimage Genome Study of Neuroplasticity Associated With Microgravity
Status: ACTIVE_NOT_RECRUITING
Conditions: Microgravity|Neuroplasticity|MRI|Repeatable Battery for the Assessment of Neuropsychological Status
Interventions: OTHER: Head-Down tilt Bed Rest test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Timing and Resistance Exercise: Impact on Eating and Metabolism
Status: NOT_YET_RECRUITING
Conditions: Circadian Rhythm|Energy Balance|Appetitive Behavior|Food Reward
Interventions: OTHER: The exercise in morning|OTHER: The exercise in evening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulated Mid-frequency Whole-body Electromyostimulation and Nutritional Therapy in Gastrointestinal Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Oesophageal Cancer|Gastric Cancer|Duodenal Cancer|Colorectal Cancer
Interventions: OTHER: mid-frequency whole-body electromyostimulation (WB-EMS)|OTHER: conventional exercise training|OTHER: nutritional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Durvalumab With Radiotherapy for Adjuvant Treatment of Intermediate Risk SCCHN
Status: ACTIVE_NOT_RECRUITING
Conditions: Larynx|Lip|Oral Cancer|Digestive Organs--Diseases
Interventions: DRUG: Durvalumab|RADIATION: Intensity Modulated Radiotherapy Treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Feasibility of RESCUE: An Adjunctive HAI-Based Intervention for Veterans With PTSD
Status: COMPLETED
Conditions: PTSD
Interventions: BEHAVIORAL: RESCUE|BEHAVIORAL: Prolonged Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Adherence to Treatment With Glucophage Sachets Versus Tablets in Diabetes Type 2 Patients Previously Treated With Metformin Tablets
Status: WITHDRAWN
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Glucophage|DRUG: Glucophage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine's Efficiency in the Treatment of Chronic Pain: Kynurenin Pathway
Status: UNKNOWN
Conditions: Neuralgia|Chronic Pain|Inflammation
Interventions: DRUG: Ketamine 10 MG/ML|DRUG: Placebos|DRUG: Midazolam 1 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Management of Closed Surgical Incisions Resulting From Incisional Hernia Repair and/or Functional Panniculectomy Using the Prevena™ Customizable™ Dressing
Status: TERMINATED
Conditions: Herniorrhaphy|Abdominoplasty
Interventions: DEVICE: Customizable Dressing with ActiV.A.C. Therapy Unit|DEVICE: Standard of Care Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Colonoscopy Booklet:Effect of a Recipe Resource on Quality of Colonoscopy Bowel Preparation and Patient Experience
Status: COMPLETED
Conditions: Bowel Preparation|Patient Experience|Patient Satisfaction
Interventions: OTHER: A recipe booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Monovalent Chimpanzee Adenoviral-Vectored Marburg Virus Vaccine in Healthy Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Marburg Virus Disease
Interventions: BIOLOGICAL: cAd3-Marburg vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fixed Versus Adjustable Loop in ACL Reconstruction
Status: ACTIVE_NOT_RECRUITING
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: PROCEDURE: Adjustable versus fixed suspensory loop femoral side graft fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Method VALIDation and Evaluation of Non-radioactive Methods to Measure Glomerular Filtration Rate
Status: NOT_YET_RECRUITING
Conditions: Kidney Function Issue|Diagnosis|Chronic Kidney Diseases
Interventions: DRUG: Iohexol|DIAGNOSTIC_TEST: 125I-iothalamate and 131I-hippuran
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Straumann Bone Ceramic Versus BioOss in Sinus Elevation
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially|Alveolar Bone Loss
Interventions: DEVICE: Straumann Bone Ceramic|DEVICE: BioOss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Prevalence of Sexual Dysfunction in Women After Rectal Cancer Surgery and Analysis of the Impact of a Sexologist Intervention
Status: NOT_YET_RECRUITING
Conditions: Rectal Tumor|Women|Sexuality|Life Quality
Interventions: OTHER: sexologist consult|OTHER: standart of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of a Computerised Exercise System on Functionality of the Arm,Cognition and Quality of Life in Stroke Patients
Status: COMPLETED
Conditions: Stroke|Neuronal Plasticity|Hemiplegia
Interventions: DEVICE: Rejoyce (Rehabilitation Joystick for Computerized Exercise)|OTHER: Conventional physical therapy|OTHER: Occupational therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravesical Gemcitabine and Docetaxel for Low Grade Intermediate Risk Bladder Cancer
Status: NOT_YET_RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: Docetaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Huaiqihuang Granule in the Treatment of Primary Glomerulonephritis of Stage CKD3
Status: RECRUITING
Conditions: Renal Insufficiency, Chronic
Interventions: DRUG: Huaiqihuang granules|DRUG: Valsartan capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Interdental Papilla Reconstruction Using Injectable Autogenous Fat Versus Hyaluronic Acid Filler.
Status: NOT_YET_RECRUITING
Conditions: Hyaluronic Acid|Fat Graft
Interventions: PROCEDURE: Fat graft injection|PROCEDURE: Hyaluronic acid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TENS Analgesia During Outpatient Urethral Bulking for Stress Urinary Incontinence.
Status: NOT_YET_RECRUITING
Conditions: Stress Incontinence Female|Urinary Incontinence|Urinary Incontinence,Stress|Pain|Pain Acute
Interventions: PROCEDURE: TENS|PROCEDURE: Control TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PHYSICAL ACTIVITY AS COPING STRATEGY FOR ACADEMIC STRESS AMONG UNDERGRADUATE FEMALE COLLEGIATE STUDENT
Status: COMPLETED
Conditions: Physical Activity and Stress
Interventions: OTHER: Light physical activity|OTHER: Moderate physical activity|OTHER: Vigorous physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Visilizumab in Subjects With Intravenous Steroid-Refractory Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: visilizumab|DRUG: visilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Saturated Fat (Desi Ghee) on Gut-Liver Axis in Alcoholic Hepatitis
Status: COMPLETED
Conditions: Alcoholic Hepatitis
Interventions: DIETARY_SUPPLEMENT: Saturated Fat- Desi Ghee (Clarified Butter)|DIETARY_SUPPLEMENT: Soyabean Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Importance of Inflammatory Markers Calculated From Preoperative and Postoperative Peripheral Blood Results in the Diagnosis and Treatment of Patients Operated for Hydatid Cyst of the Lung (Lung Echinococcus Granulosus)
Status: RECRUITING
Conditions: Lung Hydatid Cyst
Interventions: OTHER: Operated patients with hydatid cyst of the lung
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 3 Study to Evaluate Xilonix as an Anticancer Therapy in Patients With Symptomatic Colorectal Cancer
Status: COMPLETED
Conditions: Symptomatic Colorectal Cancer|Advanced Colorectal Cancer|Colorectal Cancer With Cachexia
Interventions: BIOLOGICAL: Xilonix|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Safety of a Novel Scaffold Biomaterial
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Neuropathy|Chronic Inflammatory Demyelinating Polyradiculoneuropathy|Vasculitic Neuropathy (Disorder)|Amyloidosis|Hereditary Neuropathy|Sarcoid Neuropathy
Interventions: DEVICE: Biopsy + Nerve Repair|PROCEDURE: Biopsy Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Influence of Protein Supplements on Serum Insulin-like Growth Factor-I Levels in Women With Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa
Interventions: DIETARY_SUPPLEMENT: Oral protein supplement (Tested product)|DIETARY_SUPPLEMENT: Iso-caloric supplement (Control product)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Community Based Psychological Intervention For Persons Living With Disabilities
Status: COMPLETED
Conditions: Physical Condition, Minor Psychological Component|Psychological Distress
Interventions: BEHAVIORAL: Indigenously adapted problem management plus (IA-PM+)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenetic Implementation Trial in Veterans With Treatment Refractory Depression
Status: COMPLETED
Conditions: Depression|Depressive Disorder|Depressive Disorder, Major|Depression, Bipolar|Depressive Episode
Interventions: DIAGNOSTIC_TEST: Mental Health DNA Insight Test (Pathway Genomics)|DIAGNOSTIC_TEST: Sham Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of RSVpreF Coadministered With SIIV in Adults ≥65 Years of Age
Status: COMPLETED
Conditions: Respiratory Syncytial Virus
Interventions: BIOLOGICAL: RSVpreF Vaccine|OTHER: Placebo|BIOLOGICAL: Seasonal Inactivated Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Octreotide on Blood and Iron Requirements in Patients With Anemia Due to Angiodysplasias
Status: COMPLETED
Conditions: Angiodysplasia|Vascular Malformations|Gastrointestinal Hemorrhage|Anemia
Interventions: DRUG: Octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT