pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of an Low Carbon High Fat Diet on Pain- and Quality of Life in Patients With Lipedema
Status: COMPLETED
Conditions: Lipedema|Obesity, Morbid
Interventions: DIETARY_SUPPLEMENT: Low carbohydrate high fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Special Drug Use Surveillance of Vonoprazan for "Prevention of Recurrence of Gastric/Duodenal Ulcer in Patients Receiving Non-steroidal Anti-inflammatory Drugs: Long-term Use"
Status: COMPLETED
Conditions: A History of Gastric or Duodenal Ulcers
Interventions: DRUG: Vonoprazan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bexarotene and Fenretinide as Addition to Antipsychotic Treatment in Schizophrenia Patients
Status: WITHDRAWN
Conditions: Schizophrenia|Schizoaffective Disorder|Cognition
Interventions: DRUG: Bexarotene|DRUG: Fenretinide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REaCT-vascular Access Her2 Negative Vascular Access Strategies for (Neo) Adjuvant Breast Cancer Treatment Without Trastuzumab
Status: COMPLETED
Conditions: Breast Cancer|Cancer
Interventions: DEVICE: venous access PORT or PICC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase 3 Trial Evaluating the Safety, Tolerability, and Immunogenicity of a 13-valent Pneumococcal Conjugate Vaccine in Japanese Elderly Adults Aged 65 Years Old and Older
Status: COMPLETED
Conditions: Pneumococcal Vaccines|Pneumococcal Conjugate Vaccine
Interventions: BIOLOGICAL: 13-valent pneumococcal conjugate vaccine|BIOLOGICAL: 23-valent pneumococcal polysaccharide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multiple Dose Escalating Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP1941
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ASP1941|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in Women
Status: COMPLETED
Conditions: Cognitive Impairment|Executive Dysfunction|Endothelial Dysfunction|Cardiovascular Disease
Interventions: DRUG: Leuprolide acetate|DRUG: Estradiol|DRUG: Medroxyprogesterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Immunogenicity Study of ChimeriVax West Nile Vaccine in Healthy Adults
Status: COMPLETED
Conditions: West Nile Fever
Interventions: BIOLOGICAL: ChimeriVax-WN02 vaccine|BIOLOGICAL: ChimeriVax-WN02 vaccine|BIOLOGICAL: ChimeriVax-WN02 vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Comparison of Two Albumin Administration Schedules for Spontaneous Bacterial Peritonitis (SBP)
Status: UNKNOWN
Conditions: Spontaneous Bacterial Peritonitis|Cirrhosis
Interventions: DRUG: Standard Care|DRUG: Experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance Analysis in Down Syndrome on Mobile Phone
Status: COMPLETED
Conditions: Down Syndrome
Interventions: BEHAVIORAL: Down Syndrome Group 1|BEHAVIORAL: Down Syndrome Group 2|BEHAVIORAL: Typical Development Group 1|BEHAVIORAL: Typical Development Group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Negative-pressure Wound Therapy Use in Conflict-related Extremity Wounds
Status: COMPLETED
Conditions: Wounds, Gunshot|Arm Injuries|Leg Injuries|Wound Infection
Interventions: DEVICE: Vaccum Assisted Closure device|PROCEDURE: Conventional wound dressings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Phimosis With Topical Steroid Cream -Double-blind, Randomized, Placebo-controlled Study
Status: UNKNOWN
Conditions: Phimosis
Interventions: DRUG: Mometasone furoate cream|DRUG: moisturizing cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Islet Autotransplantation in Patients at Very High-risk Pancreatic Anastomosis
Status: COMPLETED
Conditions: Postpancreatectomy Hyperglycemia
Interventions: PROCEDURE: Pancreaticoduodenectomy with pancreatic anastomosis|PROCEDURE: Total pancreatectomy with islet autotransplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of a Tetravalent Dengue Vaccine Booster Injection in Subjects Who Previously Completed a 3-dose Schedule
Status: COMPLETED
Conditions: Dengue Fever|Dengue Hemorrhagic Fever
Interventions: BIOLOGICAL: CYD Dengue Vaccine (5 dose formulation)|BIOLOGICAL: Placebo, NaCl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Improving Survivorship and Health-related Quality of Life in Patients With Primary Brain Tumours
Status: NOT_YET_RECRUITING
Conditions: Hypopituitarism|Radiotherapy-Induced Hypopituitarism|Brain Tumor
Interventions: DIAGNOSTIC_TEST: Dynamic testing of Pituitary Function
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of an Infant Formula on Infant Growth, Health and Immune Functions
Status: UNKNOWN
Conditions: Health|Growth|Immune Functions
Interventions: OTHER: Infant formula supplemented with bovine milk Osteopontin|OTHER: Standard infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating the Potential of DVS SR to Inhibit the CYP2D6 Pathway
Status: COMPLETED
Conditions: Depressive Disorder, Major|Diabetic Neuropathies|Fibromyalgia|Vasomotor Symptoms
Interventions: DRUG: desvenlafaxine sustained release (DVS SR)|DRUG: Paroxetine|DRUG: Codeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Thermal Image Guided Laser Interstitial Thermal Therapy in Treating Patients With Breast Cancer
Status: WITHDRAWN
Conditions: Ductal Breast Carcinoma in Situ|Invasive Ductal Breast Carcinoma|Stage IA Breast Cancer|Stage IB Breast Cancer
Interventions: PROCEDURE: magnetic resonance thermal imaging|PROCEDURE: laser interstitial thermal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: N-Acetyl Cysteine Supplementation in Therapy Refractory Major Depressive Disorders
Status: UNKNOWN
Conditions: Major Depressive Disorders
Interventions: DRUG: N-acetylcysteine|DRUG: placebo comparator of N-acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRP Versus HA IN OSTEOARTHRITIS OF THE PATELLOFEMORAL JOINT
Status: RECRUITING
Conditions: Patellofemoral Osteoarthritis
Interventions: PROCEDURE: Autologous PRP injection|PROCEDURE: HA injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of NVN1000 Topical Gel and Topical Gel Vehicle in the Treatment of Moderate to Severe Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris|Acne
Interventions: DRUG: NVN1000|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Procollagen-3 Driven Corticosteroids for Persistent Acute Respiratory Distress Syndrome
Status: TERMINATED
Conditions: Persistent ARDS
Interventions: DRUG: Methylprednisolone|DRUG: Methylprednisolone placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Imaginal Exposure and Imagery Rescripting in Treatment of Posttraumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Imaginal exposure|BEHAVIORAL: Imagery rescripting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemo-hormonal Therapy Combined With Radical Prostatectomy for Locally Advanced Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer|Chemotherapy Effect|Hormone Sensitive Prostate Cancer|Locally Advanced Prostate Carcinoma
Interventions: DRUG: Neoadjuvant chemotherapy combined with hormone therapy|DRUG: Neoadjuvant hormone therapy|PROCEDURE: Radical Prostatectomy (RP)+ extended lymph node dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Grade Inflammation in Childhood Obesity : an Independent Risk Factor for Endothelial Dysfunction
Status: UNKNOWN
Conditions: Obesity, Childhood|Obesity|Endothelial Dysfunction|Cardiovascular Risk Factor|Inflammation
Interventions: DIAGNOSTIC_TEST: Anthropometry|DIAGNOSTIC_TEST: Blood pressure|DIAGNOSTIC_TEST: Peripheral arterial tonometry|OTHER: Questionnaire|DIAGNOSTIC_TEST: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Pre-procedure Planning for Liver Biopsy or Radiofrequency Ablation Using CT or MR/US Fusing Imaging
Status: COMPLETED
Conditions: Liver Mass|Liver Fibroses
Interventions: DEVICE: CT/US fusion|DEVICE: ultrasound shear wave elastography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of the Oral HIV Entry Inhibitor Vicriviroc in HIV Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: SCH-D (vicriviroc)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Immunogenicity and Safety of a Challenge Dose of HBVAXPRO in Healthy Children Vaccinated 10 Years Ago With 3 Doses of HEXAVAC or INFANRIX HEXA
Status: COMPLETED
Conditions: Virus Diseases|Hepatitis B
Interventions: BIOLOGICAL: HBVAXPRO 5µg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Zolpidem Postmarketing Study in Adolescent Patients With Insomnia
Status: COMPLETED
Conditions: Insomnia
Interventions: DRUG: Zolpidem (Myslee®)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality in Individuals With Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: BEHAVIORAL: DMD gesture task|BEHAVIORAL: DMD button-press task|BEHAVIORAL: Control group gesture task|BEHAVIORAL: Control group button-press task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Whole Breast Screening Ultrasound and Contrast Enhanced Mammography for Supplemental Breast Cancer Screening
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer Screening
Interventions: DEVICE: contrast enhanced digital mammography (CEDM)|DEVICE: whole breast screening ultrasound (WBUS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vagal Nerve Stimulation in mTBI
Status: RECRUITING
Conditions: PTSD|mTBI
Interventions: DEVICE: sham stimulation|DEVICE: nVNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of A Venetoclax-based, Anthracycline-free Regimen in Newly Diagnosed CBFβ::MYH11(+) AML
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Venetoclax|DRUG: azacitidine|DRUG: decitabine|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact Evaluation of Personalized Oral Hygiene Education on Periodontal Patients Stage I/II/III
Status: UNKNOWN
Conditions: Periodontal Disease Stage I/II/III
Interventions: BEHAVIORAL: Control group: Dental Model|BEHAVIORAL: Computer-assisted teaching format group|BEHAVIORAL: Plaque-disclosing group|BEHAVIORAL: Intra-oral camera group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effectiveness of Stellate Ganglion Block in Managing Dysphagia in Patients With Medullary Infarction
Status: NOT_YET_RECRUITING
Conditions: Bulbar Palsy
Interventions: BEHAVIORAL: Comprehensive rehabilitation|PROCEDURE: Injection|DRUG: Lidocaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety, PK, and Exploratory Efficacy of SP-624 in Acutely Psychotic Adult Subjects With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: SP-624|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Perioperative Paclitaxel in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive Cytology
Status: RECRUITING
Conditions: Gastric Adenocarcinoma|Carcinomatosis
Interventions: DRUG: Paclitaxel|DRUG: Dexamethasone|DRUG: Diphenhydramine|DRUG: Famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 4-drug Nerve Block Versus Plain Local Anesthetic for Knee and Hip Arthroplasty Analgesia in Veterans
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Bupivacaine + CBD (clonidine, buprenorphine, dexamethasone)|DRUG: Bupivacaine Only (control arm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biobehavioral Bases & Management of Metabolic Syndrome (CHARMS)
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: BEHAVIORAL: CHARMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Ixmyelocel-T in Patients With Critical Limb Ischemia (CLI)
Status: COMPLETED
Conditions: Critical Limb Ischemia
Interventions: BIOLOGICAL: Ixmyelocel-T|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Different Exercise Modalities in Adolescents With Type 1 Diabetes Using AID Systems
Status: RECRUITING
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: High Intensity Interval Exercise|BEHAVIORAL: Moderate Intensity Continous Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of SECTG Vs. Laser-DGG in Management of Gingival Recessions.
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Tunneling with laser de-epithelized gingival graft|PROCEDURE: Tunnelingwith subepithelial connective tissue graf
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sildenafil Citrate Compared to Estrogen as Adjuvant Therapy for Unexplained Infertility
Status: COMPLETED
Conditions: Subfertility, Female
Interventions: DRUG: estrogen therapy|DRUG: Sildenafil|DRUG: Clomiphene Citrate 50mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Restorative Neuromodulation for Upper Extremity Functions
Status: COMPLETED
Conditions: Traumatic Brain Injury|Cervical Spinal Cord Injury
Interventions: OTHER: Trans-spinal Electrical Stimulation (tsES)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of the Efficacy and Safety of Transhepatic Arterial Chemoembolization Combined With Tislelizumab and Lenvatinib in Patients With Advanced Unresectable Hepatocellular Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Tislelizumab|Lenvatinib|TACE|Advanced Unresectable Hepatocellular Carcinoma
Interventions: COMBINATION_PRODUCT: Tislelizumab and Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Adverse Events and the Movement of Oral Venetoclax Tablet Through the Body of Female Participants Aged 18-75 Years With Impaired Renal Function
Status: COMPLETED
Conditions: Renal Impairment|Renal Disease
Interventions: DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Physiotherapy Treatment of Shoulder Rotator Cuff Tendinopathies. Global Postural Reeducation or Aerobic Exercise?
Status: RECRUITING
Conditions: Rotator Cuff Tendinosis
Interventions: OTHER: GPR Group|OTHER: Aerobic Exercice Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of LCAR-C182A Cells in the Treatment of Advanced Gastric Cancer and Pancreatic Ductal Adenocarcinoma
Status: TERMINATED
Conditions: Gastric Cancer|Pancreatic Ductal Adenocarcinoma
Interventions: BIOLOGICAL: LCAR-C182A cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Ticagrelor in Reducing the Number of Days With Pain in Patients With Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: Ticagrelor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Short Course Vaginal Cuff Brachytherapy in Treating Participants With Stage I-II Endometrial Cancer
Status: RECRUITING
Conditions: Endometrial Clear Cell Adenocarcinoma|Endometrial Endometrioid Adenocarcinoma|Endometrial Serous Adenocarcinoma|Stage I Uterine Corpus Cancer|Stage IA Uterine Corpus Cancer|Stage IB Uterine Corpus Cancer|Stage II Uterine Corpus Cancer|Uterine Corpus Carcinosarcoma|Uterine Corpus Sarcoma
Interventions: RADIATION: Vaginal Cuff Brachytherapy|RADIATION: Short course vaginal cuff brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Sulopenem-etzadroxil/Probenecid Versus Ciprofloxacin for Uncomplicated Urinary Tract Infection in Adult Women
Status: COMPLETED
Conditions: Uncomplicated Urinary Tract Infections
Interventions: DRUG: Sulopenem-Etzadroxil/Probenecid|DRUG: Ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MEHD7945A in Combination With Cisplatin and 5-Fluorouracil (5-FU) or Paclitaxel and Carboplatin in Participants With Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck (R/M SCCHN)
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: 5-FU|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: MEHD7945A|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation for Eradication of CRE
Status: COMPLETED
Conditions: Antibiotic Resistant Strain|Microbial Colonization
Interventions: BIOLOGICAL: Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Anastrozole or Tamoxifen in Treating Postmenopausal Women With Ductal Carcinoma in Situ Who Are Undergoing Lumpectomy and Radiation Therapy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: anastrozole|DRUG: tamoxifen citrate|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Bevacizumab and Verteporfin (Two Different Sequences of Treatment)in Neovascular AMD
Status: COMPLETED
Conditions: Choroidal Neovascularization|Macular Degeneration
Interventions: DRUG: Verteporfin|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Iron Versus Oral Iron for the Treatment of Iron Deficiency Anemia
Status: RECRUITING
Conditions: Iron Deficiency Anemia of Pregnancy
Interventions: DRUG: Venofer 200 MG Per 10 ML Injection|DRUG: Ferrous sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: My Mobile Advice Program: A Randomized Pilot Feasibility Study
Status: COMPLETED
Conditions: Smoking Cessation|Medication Adherence
Interventions: DRUG: Varenicline|BEHAVIORAL: Cognitive-behavioral self-help|BEHAVIORAL: MyMAP (My Mobile Advice Program)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIFU Treatment of Benign Thyroid Nodules
Status: NOT_YET_RECRUITING
Conditions: Thyroid Nodule (Benign)
Interventions: DEVICE: Device: Echopulse (HIFU ablation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skin Barrier Assessment in Pregnancy and at Birth
Status: UNKNOWN
Conditions: Pregnancy Related|Allergy|Atopic Dermatitis Eczema|Asthma in Children|Food Allergy
Interventions: DIAGNOSTIC_TEST: Transepidermal water loss|DIAGNOSTIC_TEST: Skin tape stripping|DIAGNOSTIC_TEST: Blood draw|DIAGNOSTIC_TEST: Bacterial PCR swab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Detection in Tandem Endocuff Cap Trial
Status: COMPLETED
Conditions: Colonic Neoplasms|Adenomas Serrated|Colo-rectal Cancer|Colon Adenoma
Interventions: DEVICE: Endocuff|DEVICE: cap assisted colonoscopy (CAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: An Adaptive Intervention for Adolescents at Risk for Suicide: A Pilot SMART
Status: COMPLETED
Conditions: Suicide|Self Harm
Interventions: BEHAVIORAL: MI-Enhanced Safety Plan at Hospitalization (1st Component)|BEHAVIORAL: MI-Enhanced Text Boosters (2nd Component)|BEHAVIORAL: MI-Enhanced Booster Call (3rd Component)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shugan Jieyu Capsule for Insomnia Patients With Depressive Symptoms
Status: RECRUITING
Conditions: Insomnia
Interventions: DRUG: Experimental group: Shugan Jieyu Capsule combined with zolpidem|DRUG: Control group: Placebo combined with zolpidem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab, Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Stage II-IIIB Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage II Non-Small Cell Lung Cancer|Stage IIIA Non-Small Cell Lung Cancer|Stage IIIB Non-Small Cell Lung Cancer
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|DRUG: Carboplatin|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brachial Plexus Block vs. General Anesthesia for Anesthesia Anxiety Before Orthopedic Upper Extremity Surgery
Status: COMPLETED
Conditions: Orthopedic Disorder|Anxiety|Upper Extremity Injury|Surgery
Interventions: PROCEDURE: Brachial plexus block|PROCEDURE: General anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects and Safety of Taurine Granule on Blood Pressure in Prehypertensive
Status: COMPLETED
Conditions: Prehypertension
Interventions: DRUG: Taurine granule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Two Different Physiotherapy Programs in Lymphedema Following Head and Neck Cancer Treatment
Status: COMPLETED
Conditions: Head and Neck Cancer|Lymphedema of Face|Fibrosis; Skin
Interventions: OTHER: Complex decongestive physiotherapy|OTHER: Home program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Colonization of Strains L.Plantarum and L.Brevis in the Product AB-DENTALAC Chewing Gum
Status: COMPLETED
Conditions: Periodontal Disease
Interventions: DIETARY_SUPPLEMENT: AB-DENTALAC [Probiotics (study)]|DIETARY_SUPPLEMENT: Placebo (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Of An Education Plan And Adherence Follow-Up To The Exercise In Patients With COPD
Status: COMPLETED
Conditions: Patient Adherence
Interventions: BEHAVIORAL: Education plan and adherence to exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mapping the Endocrine Determinants of Ovarian Stimulation to Optimize Outcomes in Fresh Embryo Transfer Cycles
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Placebo|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and PK of Elpida® in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact of Food Intake and Drug-Drug Interactions With Other Antiviral Drugs
Status: COMPLETED
Conditions: HIV-1-infection|Hepatic Impairment
Interventions: DRUG: Elpida®|DRUG: Dolutegravir|DRUG: Sofosbuvir|DRUG: Daclatasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Aim of This Study is to Compare the Effects of Instrument-assisted Soft Tissue Mobilization (IASTM) and Extracorporeal Shock Wave Therapy (ESWT) Used in Myofascial Pain Syndrome (MPS) and to Determine Whether They Are Superior to Conservative Treatment (CT)
Status: COMPLETED
Conditions: Myofascial Pain Syndrome
Interventions: OTHER: Conservative Treatment (CT)|OTHER: Instrument-assisted Soft Tissue Mobilization (IASTM)|OTHER: Extracorporeal Shock Wave Therapy (ESWT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Daily Doses of Aspirin to Overcome Hyporesponsiveness Post Cardiac Bypass Surgery (ASACABG)- Part B
Status: COMPLETED
Conditions: Postoperative Dysfunction Following Cardiac Surgery
Interventions: DRUG: Aspirin|DRUG: Aspirin|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Tolerability of Sitagliptin/Simvastatin Fixed-dose Combination (FDC) in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-312)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Sitagliptin 100 mg/simvastatin 40 mg FDC|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Zinc L-Carnosine Mouth Rinse
Status: UNKNOWN
Conditions: Periodontal Index|Pain
Interventions: DRUG: Zinc L-Carnosine|DRUG: Chlorhexidine|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Granulocyte Colony Stimulating Factor in Embryo Transfer Outcomes
Status: RECRUITING
Conditions: Infertility|Infertility,Female|Infertility; Female, Nonimplantation|Infertility Unexplained|Infertility of Uterine Origin
Interventions: DRUG: Granulocyte Colony-Stimulating Factor (Filgrastim)|OTHER: Standard Embryo Transfer Media
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Conventional Physiotherapy and Thoracoabdominal Rebalancing in Post-operative of Myocardial Revascularization
Status: COMPLETED
Conditions: Respiratory Complication
Interventions: OTHER: Thoracoabdominal rebalancing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Finger Food, Pleasure at Your Fingertips: Randomized Pilot Study, Open-label and Parallel Groups
Status: RECRUITING
Conditions: Undernutrition|Elderly Person
Interventions: OTHER: Hand-Eating|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Buscopan on Gastrointestinal Imaging Quality With Probe-based Confocal Laser Endomicroscopy
Status: UNKNOWN
Conditions: Gastrointestinal Imaging With pCLE
Interventions: DRUG: Buscopan|DRUG: Scopolamine|DRUG: physiological saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Antibiotic Short Course for Bloodstream Infections in Acute Myeloid Leukemia Patients With Febrile Neutropenia
Status: COMPLETED
Conditions: Bloodstream Infection|Acute Myeloid Leukemia|Febrile Neutropenia
Interventions: DRUG: Antibiotic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: In-vivo Efficacy of Patient Preoperative Prep
Status: COMPLETED
Conditions: Surgical Skin Preparation
Interventions: DRUG: ZuraPrep|DRUG: ChloraPrep|DRUG: ZP Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ARIES - Ambrisentan in Patients With Moderate to Severe Pulmonary Arterial Hypertension (PAH)
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: Ambrisentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab Combined With Chemotherapy in First-line Treatment of HER2-positive Gastric Cancer
Status: UNKNOWN
Conditions: HER2-positive Gastric Cancer
Interventions: DRUG: Camrelizumab +Pyrotinib + Nab-paclitaxel + Tegafur
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study to Assess the Safety of GRF6019 Infusions in Subjects With Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease|Mild to Moderate Alzheimer Disease
Interventions: DRUG: GRF6019
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Colchicine in Atrial Fibrillation to Prevent Stroke
Status: COMPLETED
Conditions: Atrial Fibrillation|Stroke
Interventions: DRUG: Colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety And Efficacy Of 12 Weeks Of Varenicline For Smoking Cessation In Smokers With Depression
Status: COMPLETED
Conditions: Smoking Cessation|Depression
Interventions: DRUG: varenicline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Idarubicin and High-Dose Cytarabine in Treating Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: cytarabine|DRUG: idarubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Training of Pelvic Floor Muscles (MAP) on Stress Urinary Incontinence
Status: UNKNOWN
Conditions: Stress Urinary Incontinence
Interventions: PROCEDURE: Training of pelvic floor muscles|PROCEDURE: Hipopressive abdominal gymnastics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IMPENDIA- PEN VS Dianeal Only Improved Metabolic Control In Diabetic CAPD and APD Patients
Status: COMPLETED
Conditions: ESRD|Diabetes
Interventions: DRUG: Dianeal|DRUG: Physioneal|DRUG: Extraneal|DRUG: Nutrineal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Tarsorrhaphy vs Gold Weight Implant for Paralytic Lagophthalmos in Leprosy Patients
Status: COMPLETED
Conditions: Paralytic Lagophthalmos|Leprosy--Patients
Interventions: PROCEDURE: Modified Tarsorrhaphy|PROCEDURE: Gold Weight Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Patellar and Achilles Tendinopathies in Youth Basketball
Status: COMPLETED
Conditions: Injury, Knee|Injury, Ankle|Tendinopathy|Sports Injuries in Children
Interventions: OTHER: Comprehensive Follow-up|OTHER: Standard Follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Firibastat or Ramipril After Acute Myocardial Infarction for Prevention of Left Ventricular Dysfunction
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Ramipril|DRUG: Firibastat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lateral Ridge Augmentation Using a Volume Maintaining Collagen Scaffold Versus Allograft With Collagen Membrane.
Status: UNKNOWN
Conditions: Alveolar Ridge Augmentation, Dental Implants
Interventions: DEVICE: Ossix Volumax|DEVICE: FDBA with collagen membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Cetuximab With Concomitant-boost Radiotherapy in Patients With Newly Diagnosed Locally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Status: COMPLETED
Conditions: Carcinoma of the Head and Neck
Interventions: DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Term Effect of Cervical Mobilization vs Manipulation on Blood Pressure in Hypertensive Subjects
Status: COMPLETED
Conditions: Hypertension
Interventions: OTHER: cervical mobilization|OTHER: cervical manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Glargine Insulin on Glucose Control in Hospitalized Patients Who Receive Tube Feedings
Status: COMPLETED
Conditions: Type 2 Diabetes|Hyperglycemia
Interventions: DRUG: Glargine insulin vs regular insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ⅱ Study of HAIC of FOLFOX vs. Sorafenib in HCC Refractory to TACE
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: HAIC of FOLFOX|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Physiological Effect of High-Flow Nasal Cannula on Respiratory Pattern and Work of Breathing
Status: COMPLETED
Conditions: COPD
Interventions: OTHER: Esophageal and gastric balloons|OTHER: Respiratory Inductance Plethysmography (RIP) system|OTHER: Sentec transcutaneous monitoring system|DEVICE: High-flow humidified nasal oxygen delivery system|DEVICE: CPAP (Positive Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Rehabilitation Through Hippotherapy for the Management of Women After Primary Treatment of Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer Female|Side Effects|Psychological Distress|Physical Disability
Interventions: OTHER: Hippotherapy|OTHER: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity, Safety and Tolerability of CSL Limited Inactivated Influenza Vaccine in Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: CSL Trivalent Inactivated Influenza Vaccine - Thimerosal-free|BIOLOGICAL: CSL Trivalent Inactivated Influenza Vaccine with Thimerosal|BIOLOGICAL: Placebo with Thimerosal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: SOFT Block Versus Spinal Anesthesia in Patientsusing Ilizarov External Fixator
Status: COMPLETED
Conditions: Pain, Acute
Interventions: DEVICE: SOFT block group|DEVICE: spinal anesthesia group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CompRehensive Phenotypic Characterization of Patients With Scleroderma-Associated ILD and PH
Status: UNKNOWN
Conditions: Interstitial Lung Disease|Scleroderma|Pulmonary Hypertension
Interventions: DRUG: Opsumit 10 Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Out-of-Hospital Non-Invasive Ventilation for Patients With Acute Respiratory Failure
Status: COMPLETED
Conditions: Respiratory Insufficiency|Respiratory Failure
Interventions: PROCEDURE: Non-invasive-ventilation|PROCEDURE: conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemiarthroplasty Or Total Elbow Arthroplasty in the Elderly.
Status: UNKNOWN
Conditions: Distal Humerus Fracture
Interventions: OTHER: Hemiarthroplasty|OTHER: Total elbow arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BPA Levels Relationship With IVF/ICSI Outcomes in Low Ovarian Reserve
Status: COMPLETED
Conditions: Infertility Low Over Reserve|IVF|Infertility, Female
Interventions: OTHER: BPA levels
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Dexmedetomidine on Oxygenation and Lung Mechanics in Morbidly Obese Patients Undergoing Bariatric Operations
Status: COMPLETED
Conditions: Restrictive Lung Disease
Interventions: DRUG: Dexmedetomidine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Effect of Reveratrol,Folic Acid, Vitamin D, Vitamin B12 and B6 in Male Infertility
Status: UNKNOWN
Conditions: Male Infertility
Interventions: DIETARY_SUPPLEMENT: Genante
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: I am Protecting my Child From the Sun Program
Status: COMPLETED
Conditions: Skin Neoplasms|Parents|Behavior and Behavior Mechanisms|Child Behavior|Health Behavior
Interventions: BEHAVIORAL: I Am Protecting My Child from the Sun|BEHAVIORAL: SMS for sun protection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Proton SBRT and Immunotherapy for Recurrent/Progressive Locoregional or Metastatic Head and Neck Cancer
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: RADIATION: Proton Stereotactic Body Radiation Therapy (SBRT) (5 fractions; 3500-4500 cGy)|RADIATION: Proton Stereotactic Body Radiation Therapy (SBRT) (3-5 fractions; various dose and fractionation regimens depending on treatment site).|DRUG: Nivolumab 3 mg/kg IV q2 weeks|RADIATION: Proton or Photon SBRT (3-5 fractions; various dose and fractionation regimens depending on treatment site).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Brimonidine for Intraoperative Hemostasis
Status: RECRUITING
Conditions: Dermatochalasis of Eyelid|Ptosis, Eyelid|Ectropion|Entropion
Interventions: DRUG: Brimonidine Topical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Combined Application of Electrical Stimulated Antagonist Contraction During Walking (Walking Study)
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Hybrid Training System (HTS)|DEVICE: Sensory TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Study of ZYN002 Administered as a Transdermal Gel to Children and Adolescents With 22q11.2 Deletion Syndrome
Status: COMPLETED
Conditions: 22Q Deletion Syndrome
Interventions: DRUG: ZYN002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Imaging of Gastrin Releasing Peptide Receptors Using Labeled Technetium-99m DB8
Status: RECRUITING
Conditions: Prostate Cancer|Breast Cancer
Interventions: DRUG: Intravenous injection of [99mTc]Tc-DB8
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Dapagliflozin Effects on Epicardial Fat
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Dapagliflozin|DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glutamine in Treating Side Effects in Children Who Are Undergoing Stem Cell Transplantation
Status: COMPLETED
Conditions: Oral Complications|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DIETARY_SUPPLEMENT: glutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hard-soled Shoe Versus Short Leg Walking Cast for a Fifth Metatarsal Avulsion Fracture: A Randomized Multicenter Noninferiority Trial
Status: UNKNOWN
Conditions: Metatarsal Fracture|Treatment
Interventions: PROCEDURE: Protected weightbearing in a hard-soled shoe|PROCEDURE: Protected weightbearing in a short leg walking cast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Biomarkers in Patients With Advanced Hepatocellular Carcinoma Treated With Atezolizumab Plus Bevacizumab
Status: RECRUITING
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: atezolizumab plus bevacizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p