pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Promotion of Physical Activity in Adolescents With Intellectual and Developmental Disabilities
Status: COMPLETED
Conditions: Adolescent Behavior|Intellectual Disability|Down Syndrome|Physical Activity
Interventions: BEHAVIORAL: Group Exercise Sessions|BEHAVIORAL: Individual Support Sessions|BEHAVIORAL: Facebook Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Varicose Vein Education and Informed coNsent (VVEIN) Study
Status: COMPLETED
Conditions: Varicose Veins
Interventions: OTHER: Standard Consent|OTHER: Digital health education tool (dHET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison Between a Two Person Insertion With Lateral Rotation Technique of LMA and the Classic Technique
Status: SUSPENDED
Conditions: Airway Complication of Anesthesia
Interventions: DEVICE: standard LMA insertion|DEVICE: New technique LMA insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Procrit Versus Placebo to Determine Efficacy in Pre-Operative Major Surgical Oncology Operations
Status: WITHDRAWN
Conditions: Cancer
Interventions: DRUG: Procrit|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: S0819: Carboplatin and Paclitaxel With or Without Bevacizumab and/or Cetuximab in Treating Patients With Stage IV or Recurrent Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Recurrent Large Cell Lung Carcinoma|Recurrent Lung Adenocarcinoma|Recurrent Squamous Cell Lung Carcinoma|Stage IV Large Cell Lung Carcinoma|Stage IV Lung Adenocarcinoma|Stage IV Squamous Cell Lung Carcinoma
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Carboplatin|BIOLOGICAL: Cetuximab|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 7 Day Continuous Parathyroid Hormone IV Infusion
Status: COMPLETED
Conditions: Osteoporosis|Bone Diseases, Endocrine|Hyperparathyroidism
Interventions: DRUG: Parathyroid Hormone (1-34)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Glycemic and Insulinemic Response of Pasta Products in Comparison to Asian Foods
Status: COMPLETED
Conditions: Diabetes
Interventions: OTHER: Glucose Reference 1|OTHER: Glucose Reference 2|OTHER: Glucose Reference 3|OTHER: Semolina Penne|OTHER: Wholegrain Penne|OTHER: Semolina Spaghetti|OTHER: Wholegrain Spaghetti|OTHER: Jasmine Rice|OTHER: Asian Noodles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Timing of Bridge Plate Removal and Distal Radius Fracture Outcomes
Status: RECRUITING
Conditions: Distal Radius Fracture
Interventions: PROCEDURE: Dorsal Spanning Bridge Plate Fixation|PROCEDURE: Dorsal Spanning Bridge Plate Removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Complement Regulation to Undo Systemic Harm in Preeclampsia
Status: TERMINATED
Conditions: Preeclampsia|Severe Preeclampsia|Eculizumab|HELLP|HELLP Syndrome|HELLP Syndrome Second Trimester|Pregnancy Related|AHUS|PNH|Complement Regulatory Factor Defect|Complement Abnormality|HELLP Syndrome Third Trimester
Interventions: DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Epidemiological Study to Assess Performance of Using Healthcare Tools to Understand Genital Herpes Simplex Virus-2 (HSV-2) in Patients ≥ 18 Years of Age in the United States and Europe.
Status: ACTIVE_NOT_RECRUITING
Conditions: Herpes Genitalis
Interventions: PROCEDURE: Blood sampling|PROCEDURE: Anogenital lesion swab collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TIL Therapy Combined With Pembrolizumab for Advanced or Metastatic Refractory Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer|Lung Cancer Metastatic|Lung Cancer, Non-small Cell|Lung Cancer Recurrent
Interventions: BIOLOGICAL: Tumor Infiltrating Lymphocytes (TIL)|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Interleukin-2|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Inhaled Pre-prandial Human Insulin in Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: rosiglitazone|DRUG: inhaled human insulin|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Safety and Efficacy of Cefdinir Oral Suspension Versus Azithromycin in Pediatric Subjects With Acute Otitis Media
Status: COMPLETED
Conditions: Acute Otitis Media
Interventions: DRUG: cefdinir (Omnicef)|DRUG: azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Computer Guided Esthetic Crown Lengthening
Status: COMPLETED
Conditions: Altered Passive Eruption of Teeth|Guided Surgery|Gummy Smile
Interventions: PROCEDURE: Conventional Esthetic crown lengthening|PROCEDURE: Computer guided Esthetic crown lengthening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MAgicTouch™ Intervention Leap for Dialysis Access (MATILDA) Trial
Status: COMPLETED
Conditions: Dialysis Access Malfunction|End Stage Renal Failure on Dialysis|End Stage Renal Disease|Fistulas Arteriovenous|Stenosis
Interventions: DEVICE: AVFistuloplasty with Sirolimus coated balloon
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Maintaining Optimal HVNI Delivery Using Automatic Titration of Oxygen in Preterm Infants
Status: TERMINATED
Conditions: Infant, Premature|Neonatal Respiratory Distress|Oxygen Saturation|Bronchopulmonary Dysplasia
Interventions: DEVICE: Automated Control|DEVICE: Manual Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Pharmacokinetics, Safety and Tolerability of Topiramate in Infants (Age 1-24 Months) With Refractory Partial-onset Seizures
Status: COMPLETED
Conditions: Seizures
Interventions: DRUG: Topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: NESBID: Neuro-Stimulation of the Brain in Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Depressive Disorder, Major|Depressive Disorder, Treatment-Resistant|Transcranial Direct Current Stimulation|Electric Stimulation Therapy
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Pioglitazone Compared To Glyburide on Liver Function
Status: COMPLETED
Conditions: Diabetes Mellitus|Liver
Interventions: DRUG: Pioglitazone|DRUG: Glyburide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Implant Stability, Soft & Hard Tissue Healing Around UV Activated vs Conventional Implants
Status: RECRUITING
Conditions: UV Dental Implant
Interventions: PROCEDURE: conventional implant|PROCEDURE: UV implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tideglusib in Congenital Myotonic Dystrophy
Status: COMPLETED
Conditions: Congenital Myotonic Dystrophy
Interventions: DRUG: Tideglusib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Ankle-Brachial Index Measurement Using a Specific Oscillometric Device vs. the Doppler Method
Status: COMPLETED
Conditions: Peripheral Arterial Disease, Ankle Brachial Index, Doppler
Interventions: DIAGNOSTIC_TEST: Measure ankle brachial index (ABI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Influence of Rapeseed Proteins on the Postprandial Metabolic Response
Status: COMPLETED
Conditions: Health, Subjective
Interventions: DIETARY_SUPPLEMENT: rapeseed or soy protein or no protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Respiratory Training in Low Back Pain
Status: COMPLETED
Conditions: Ultrasonography|Low Back Pain
Interventions: OTHER: Bilateral and simultaneous diaphragm ultrasonography reeducation plus inspiratory training|OTHER: Isolated inspiratory training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Myofascial Release Technique In Patients With Unilateral Cervical Radiculopathy
Status: COMPLETED
Conditions: Cervical Radiculopathy|Cervical Radicular Pain|Cervical; Hernia|Cervical Disc Disease|Cervical Disc Herniation|Pain
Interventions: OTHER: Myofascial Release Technique|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of Optimum Time for Intravenous Cannulation in Children With Dexmedetomidine Premedication
Status: COMPLETED
Conditions: Cannulation|Sevoflurane Induction|Dexmedetomidine
Interventions: PROCEDURE: Optimum time for intravenous cannulation in children premedicated with dexmedetomidine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 4 Study to Evaluate Response to Treatment and Safety of Paliperidone Extended-Release in Participants With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone extended-release (ER)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daily Irrigation With Silicone Hydrogel Contact Lens Continuous Wear
Status: COMPLETED
Conditions: Corneal Epithelial Permeability
Interventions: DRUG: Daily irrigation|DEVICE: 30-day SiH CW
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: TD-3504 SAD in Healthy Subjects and Subjects With Ulcerative Colitis (UC)
Status: COMPLETED
Conditions: Active Mild Ulcerative Colitis, Active Moderate Ulcerative Colitis, Healthy Subjects
Interventions: DRUG: TD-3504|DRUG: 15N2-tofacitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Ventilation Homogeneity as a Marker of Small Airway Disease in Active Smokers
Status: COMPLETED
Conditions: Lung Function Testing|Cigarette Smoking|Single-photon Emission Computed Tomography (SPECT)|Ventilation Homogeneity|Lung Disease Prevention
Interventions: DIAGNOSTIC_TEST: SPECT/CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparative Study Between Honey and Alcohol as Topical Skin Disinfectant
Status: NOT_YET_RECRUITING
Conditions: Disinfectant Causing Toxic Effect
Interventions: OTHER: Alcohol sterilization|OTHER: Honey sterilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Reduce Sitting in Older Adults Undergoing Hip or Knee Replacements
Status: COMPLETED
Conditions: Orthopedic Disorder|Arthropathy of Knee|Arthropathy of Hip|Sedentary Lifestyle|Physical Activity|Osteoarthritis
Interventions: BEHAVIORAL: Sedentary behaviour reduction using motivational interviewing, education, individualised feedback, goal-setting, self-monitoring, environmental modification, and supportive phone calls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Efficacy of Cranial Electrotherapy Stimulation in Mitigating Anxiety-induced Cognitive Deficits
Status: ACTIVE_NOT_RECRUITING
Conditions: Anxiety|Cognitive Deficit
Interventions: DEVICE: Cranial Electrotherapy Stimulation|DEVICE: Sham Cranial Electrotherapy Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Can Synbiotic Use Effect Gut Bacteria and the Immune Response in Older People
Status: COMPLETED
Conditions: Aging
Interventions: DIETARY_SUPPLEMENT: Synbiotic (Synergy 1/B. longum)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Increased Risk of VTE and Higher Hypercoagulability in Patients Recovered in ICU and in Medical Ward for COVID-19
Status: COMPLETED
Conditions: COVID-19 Disease|Thromboembolism, Venous
Interventions: DRUG: thromboprophylaxis with low-molecular-weight heparin or fondaparinux
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Binaural Beat Stimulation to Improve Patient Outcome After Surgery and Anesthesia
Status: RECRUITING
Conditions: Preoperative Anxiety|Perioperative Complication
Interventions: OTHER: Binaural Beat Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Interaction Between Maraviroc And Fosamprenavir/Ritonavir In Healthy Subjects
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Maraviroc|DRUG: Fosamprenavir/ritonavir|DRUG: Maraviroc + Fosamprenavir/ritonavir|DRUG: Maraviroc|DRUG: Fosamprenavir/ritonavir|DRUG: Maraviroc + Fosamprenavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Tolerability of EP0042
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Chronic Myelomonocytic Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: EP0042
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Positioning of Local Anaesthetic in Femoral Nerve Block Prior to Hip Surgery
Status: COMPLETED
Conditions: Fractured Neck of Femur
Interventions: PROCEDURE: Femoral nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Onabotulinum Toxin A in Direct Brow Lift
Status: ACTIVE_NOT_RECRUITING
Conditions: Direct Brow Lift|Scarring
Interventions: DRUG: Botox Injectable Product|OTHER: No intervention (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: In Vivo Efficacy of Artemether-Lumefantrine, Amodiaquine-Artesunate, Dihydroartemisinin-Piperaquine, and Pironaridine-Artesunate in Mozambique
Status: ACTIVE_NOT_RECRUITING
Conditions: Malaria
Interventions: DRUG: AL (Coartem)|DRUG: AS-AQ (Carsucam)|DRUG: DHP|DRUG: PA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Describe the Safety, Reactogenicity, and Immunogenicity of Herpes Zoster IN001 mRNA Vaccine (IN001) in Healthy Participants
Status: RECRUITING
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: HZ Vaccine (IN001)|BIOLOGICAL: Placebo|BIOLOGICAL: Shingrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Soy Isoflavones to Improve the Metabolism of Glucose and Lipids
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Daidzein|DIETARY_SUPPLEMENT: Genistein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Can Pan-Colonic Chromoendoscopy (PCC) Improve Adenoma Detection Rate in FIT-Positive-Patients: A Randomized Study
Status: UNKNOWN
Conditions: Colon Adenoma
Interventions: DIAGNOSTIC_TEST: Chromoendoscopy|DIAGNOSTIC_TEST: High definition white light colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Niraparib Combined With Brivanib or Toripalimab in Patients With Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: DRUG: niraparib combined with brivanib|DRUG: niraparib combined with toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Advent™ Cervical Disc Versus ACDF for Treatment of One Level Degenerative Disc Disease (IDE Study)
Status: TERMINATED
Conditions: Cervical Degenerative Disc Disease
Interventions: DEVICE: Cervical Artificial Disc (Advent™ Cervical Disc)|DEVICE: Hallmark™ Anterior Cervical Plate System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Implant Placement With Corticocancellous Bone Block vs Mineralized Plasmatic Matrix in Maxillary Sinus Lifting
Status: NOT_YET_RECRUITING
Conditions: Maxillary Sinus Floor Elevation
Interventions: PROCEDURE: Open sinus lifting|PROCEDURE: Collecting blood sample|PROCEDURE: Bone graft harvesting|PROCEDURE: Autogenous corticocancellous block graft|PROCEDURE: Mineralized plasmatic matrix graft|DEVICE: Centrifuge|DEVICE: ACM bur
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Educational Videos Reduce Maternal Anxiety Whose Children Received Congenital Heart Disease Surgery
Status: COMPLETED
Conditions: Educational Videos|Maternal Anxiety|Surgery|Congenital Heart Disease in Children|Maternal Depression
Interventions: OTHER: Preoperative educational videos plus routine education|OTHER: Preoperative routine education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Efficacy of Lapaquistat Acetate Alone or Combined With Rosuvastatin in Subjects With Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Lapaquistat acetate and rosuvastatin|DRUG: Lapaquistat acetate and rosuvastatin|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Foot Exercises in Patellofemoral Pain
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome|Anterior Knee Pain Syndrome|Pronation Deformity of the Foot|Exercise|Pain|Biomechanics|Functionality
Interventions: OTHER: SFE|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparing Polydioxanone Thread Embedding Acupuncture and Manual Acupuncture for Nasolabial Fold Reduction
Status: COMPLETED
Conditions: Aging Problems|Wrinkle
Interventions: OTHER: Manual acupuncture|OTHER: Thread embedding acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Characterization of the Serotonin 2A Receptor Selective PET Tracer [18F]MH.MZ in Patients With Neurodegenerative Diseases
Status: RECRUITING
Conditions: Neurodegenerative Diseases|Parkinson Disease|Parkinson Disease Psychosis
Interventions: DRUG: Pimavanserin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I Study of TH1 Dendritic Cell Immunotherapy for the Treatment of Cutaneous Angiosarcoma
Status: RECRUITING
Conditions: Angiosarcoma
Interventions: DRUG: Paclitaxel|BIOLOGICAL: mRNA plus Lysate-loaded Dendritic Cell Vaccine|DRUG: PEGYLATED-INTERFERON ALPHA-2A|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exemestane Plus Everolimus for Hormone-receptor Positive Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Hormone Receptor Positive Malignant Neoplasm of Breast
Interventions: DRUG: Exemestane|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infrared Wraps Effect on Oxygenation of Diabetics Arm, Feet and Lower Leg
Status: COMPLETED
Conditions: Diabetes
Interventions: DEVICE: Active IR sock|OTHER: Placebo socks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of REGN2810 (Anti-PD-1) in Patients With Advanced Malignancies
Status: COMPLETED
Conditions: Advanced Cancer|Advanced Malignancies
Interventions: DRUG: Cemiplimab|RADIATION: Hypofractionated radiotherapy|DRUG: Cyclophosphamide|DRUG: Docetaxel|DRUG: Carboplatin|DRUG: GM-CSF|DRUG: Paclitaxel|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Respiratory Imaging After Neostigmine or Sugammadex
Status: COMPLETED
Conditions: Respiratory-Gated Imaging Techniques
Interventions: DRUG: Neostigmine|DRUG: Sugammadex|DRUG: Water for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Candesartan Cilexetil in Heart Failure Assessment of Reduction in Mortality and Morbidity (CHARM Preserved)
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DRUG: Candesartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: REtinal Detachment Outcomes Study
Status: RECRUITING
Conditions: Retinal Detachment
Interventions: PROCEDURE: Pars plana vitrectomy|PROCEDURE: Pars plana vitrectomy with scleral buckle|OTHER: Sulfur hexafluoride gas tamponade|OTHER: Perfluoropropane gas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "TAKE TIME" Pioglitazone Reverses Defects in Mitochondrial Biogenesis in Patients With T2DM
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of E2007 as an Adjunctive Therapy in Levodopa Treated Parkinson's Disease Patients With Motor Fluctuations
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: DRUG: E2007
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Comparative Study of Personalized Shoulder, Knee and Ankle Brace
Status: COMPLETED
Conditions: Shoulder Injuries|Knee Injuries|Ankle Injuries
Interventions: DEVICE: Rehabilitation brace
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Transversus Abdominis Plane (TAP) Block Techniques: Surgeon vs Anesthesia - Ultrasound Guidance
Status: COMPLETED
Conditions: Post Operative Analgesia|Non-inferiority Trial
Interventions: PROCEDURE: TAP block administered by Surgery|PROCEDURE: TAP block administered by Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of a High-Protein Liquid Dietary Supplementation
Status: COMPLETED
Conditions: Malnutrition|Nutritional Status|Hospital|Hand Strength|Body Mass Index|Nutrition Assessment
Interventions: DIETARY_SUPPLEMENT: a hospital formula of normal protein liquid diet supplementation|DIETARY_SUPPLEMENT: a hospital formula of high protein liquid food supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Technical Success of IVUS Guided VCF Placement Using the LUMIFI™ With Crux® VCF System
Status: TERMINATED
Conditions: Pulmonary Embolism|Deep Vein Thrombosis
Interventions: DEVICE: vena cava filter implantation (LUMIFI with Crux VCF System)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Denufosol Tetrasodium Inhalation Solution in Patients With Cystic Fibrosis (CF) Lung Disease
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Denufosol Tetrasodium (INS37217) Inhalation Solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality and Manual Dexterity in in Patients With Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis|Physical Activity|Upper Limb|Virtual Reality|Dexterity
Interventions: BEHAVIORAL: OT+VR intervention with videogames for the upper limb (dexterity)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuroactive Steroid to Treat Depressed Mood: A Trial for People With HIV
Status: RECRUITING
Conditions: Major Depressive Disorder|Anxiety Depression|HIV
Interventions: DRUG: Placebo|DRUG: Pregnenolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pleconaril Enteroviral Sepsis Syndrome
Status: COMPLETED
Conditions: Enterovirus Infection
Interventions: OTHER: Placebo|DRUG: Pleconaril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dual-hormone Closed-loop Glucose Control in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes|Hypoglycemia
Interventions: DRUG: Glucagon|DEVICE: Closed-loop system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)
Status: RECRUITING
Conditions: Long COVID|Long COVID-19|Sleep Disturbance
Interventions: DRUG: Melatonin|DRUG: Melantonin Placebo|DEVICE: Tailored lighting (TL) Active|DEVICE: Tailored lighting (TL) Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Everolimus in Combination With Tacrolimus in Liver Transplant Recipients
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DRUG: Everolimus|DRUG: Tacrolimus|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: busulfan|DRUG: melphalan|DRUG: thiotepa|PROCEDURE: bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of Implant Stability in Low Quality Bone Following The Use of Osseodensifiers Versus Ridge Expanders
Status: UNKNOWN
Conditions: Low Bone Density
Interventions: PROCEDURE: Densah burs|PROCEDURE: Ridge expansion screws
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Laboratory Assessments of Effectiveness of Silver Diamine Fluoride (SDF) in Arresting Caries Among Children and Parental ￼Satisfaction
Status: UNKNOWN
Conditions: Caries Arrested
Interventions: OTHER: Silver Diamine Fluoride (SDF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Massage and Electroacupuncture in Chronic Lumbar Pain
Status: RECRUITING
Conditions: Back Pain|Lumbar|Anesthesia, Local|Epidural|Electroacupuncture|Massage
Interventions: DEVICE: Electroacupuncture device|DRUG: Epidural analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Painless Subconjunctival Antibiotic and Antifungal Injection in Corneal Ulcer Patients
Status: TERMINATED
Conditions: Corneal Ulcer
Interventions: PROCEDURE: Lidocaine/NSS|PROCEDURE: NSS/Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quantitative Versus Qualitative Fecal Immunochemical Tests (FIT) to Prioritize Urgency of Colonoscopy Referral
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: OTHER: Qualitative fecal immunochemical test|OTHER: Quantitative fecal immunochemical test|PROCEDURE: Colonoscopy|OTHER: Cost analysis|OTHER: Anxiety scores|OTHER: Patient satisfaction scores
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Anatomical Resection VS. Nonanatomical Resection for Colorectal Liver Metastases With Gene Mutation or Right-sidedness
Status: NOT_YET_RECRUITING
Conditions: Colorectal Carcinoma|Liver Metastases
Interventions: PROCEDURE: anatomical liver resection|PROCEDURE: nonanatomical liver resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Clinical Study of YTS109 Cell Injection in Subjects With Recurrent/Refractory Autoimmune Disease
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus|Systemic Sclerosis|Inflammatory Myopathy|Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis|Antiphospholipid Syndrome|Sjogren's Syndrome
Interventions: OTHER: YTS109
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Activates Charcoal for Patients Undergoing Invasive Procedure Delayed Due to Direct Oral Anticoagulants
Status: UNKNOWN
Conditions: Anticoagulants; Circulating, Hemorrhagic Disorder
Interventions: DRUG: Activated Charcoal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized, Augmented Cognitive Training (PACT) for Service Members and Veterans With a History of TBI
Status: UNKNOWN
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: Personalized Augmented Cognitive Training (PACT)|BEHAVIORAL: Enhanced Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study of ALXN2060 in Japanese Participants With Symptomatic ATTR-CM
Status: ACTIVE_NOT_RECRUITING
Conditions: Symptomatic Transthyretin Amyloid Cardiomyopathy
Interventions: DRUG: ALXN2060
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conservative Surgery With or Without Axillary Lymphnode Removal in Treating Women With T1N0 Breast Cancer
Status: COMPLETED
Conditions: Female Breast Neoplasms|Carcinoma, Ductal, Breast
Interventions: PROCEDURE: axillary dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ice Plant Intensive Cream for the Prevention of Hand-Foot Syndrome in Breast Cancer: Pilot Randomized Controlled Trial
Status: COMPLETED
Conditions: Hand-Foot Syndrome|Breast Cancer
Interventions: OTHER: Ice Plant Intensive Cream plus Standard Care|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The EUS ShearWave Elastography Liver Fibrosis Study
Status: COMPLETED
Conditions: Liver Fibroses
Interventions: DEVICE: ShearWave Elastography (SWE) in Endoscopic Ultrasound (EUS)|DEVICE: FibroScan|DEVICE: ALOKA ARIETTA 850 -
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study Evaluating The Role of Vonoprazan Versus Pantoprazole in Patients With Gastroesophageal Reflux Disease
Status: NOT_YET_RECRUITING
Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: DRUG: Vonoprazan 20 mg (vonseca) versus Pantoprazole 40 mg (Pantoloc)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Assess the Pharmacokinetics of GSK2798745 Tablets
Status: COMPLETED
Conditions: Heart Failure, Congestive
Interventions: DRUG: GSK2798745 Micronized API without SLS and hypermellose (Tablet A)|DRUG: GSK2798745 Micronized API with SLS and hypermellose (Tablet B)|DRUG: GSK2798745 milled API without SLS and hypermellose (Tablet C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect and Safety of Lisdexamfetamine in Children Aged 6-12 With ADHD and Autism
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Autism Spectrum Disorder
Interventions: DRUG: Lisdexamfetamine Dimesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Intervention Treatment for Patients With Mild Obstructive Sleep Apnea
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea
Interventions: BEHAVIORAL: Lifestyle intervention (physical activity and dietary counseling)|BEHAVIORAL: General information on healthy lifestyle habits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multifocal Contact Lenses Fitting Methods Comparison
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: Control Lenses (control fitting approach)|DEVICE: Test Lenses (test fitting approach)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ABSORB PHYSIOLOGY Clinical Investigation
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Bioabsorbable Vascular Solutions Everolimus Eluting Coronary Stent System (BVS EECSS)|DEVICE: XIENCE V® Everolimus Eluting Coronary Stent System (EECSS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Comparison of Metformin and Repaglinide Monotherapy in the Treatment of New Onset Type 2 Diabetes Mellitus in China
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Repaglinide|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of HRS4800 Tablets for Postoperative Analgesia After Impacted Teeth Removal Surgery.
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: HRS4800 tablets|DRUG: Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Nivolumab and Ramucirumab for Patients With Previously-Treated Mesothelioma
Status: TERMINATED
Conditions: Mesothelioma, Malignant
Interventions: DRUG: Nivolumab|DRUG: Ramucirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Hematopoietic Stem Cell Transplantation With JSP191-Based Conditioning in Participants With GATA2 Deficiency
Status: SUSPENDED
Conditions: GATA2|Immunodeficiency
Interventions: DRUG: Mycophenolate Mofetil|DRUG: Tacrolimus|DRUG: Post-Transplant Cyclophosphamide|RADIATION: Total Body Irradiation|PROCEDURE: Hematopoietic Cell Transplant|DRUG: JSP191|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-help Smartphone-delivered Cognitive Behavioral Therapy for Insomnia in People With Depression and Insomnia
Status: UNKNOWN
Conditions: Sleep Initiation and Maintenance Disorders|Depression
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia|OTHER: Waitlist Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Designs for Restaurant "Eco-Labels"
Status: COMPLETED
Conditions: Food Preferences
Interventions: BEHAVIORAL: Neutral labels|BEHAVIORAL: Numeric text-only sustainability labels|BEHAVIORAL: Endorsement text-only sustainability labels|BEHAVIORAL: Endorsement icon-only sustainability labels|BEHAVIORAL: Endorsement text-plus-icon sustainability labels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Oral Health Educational Methods in Adolescence
Status: COMPLETED
Conditions: Adolescent Behavior
Interventions: BEHAVIORAL: Oral orientation and App for smartphone|BEHAVIORAL: Oral orientation|BEHAVIORAL: Video orientation and App for smartphone|BEHAVIORAL: Video orientation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sphenopalatine Blockade Versus Clinical Treatment
Status: UNKNOWN
Conditions: Headache, Post-Dural Puncture
Interventions: DRUG: Dypirone|PROCEDURE: Sphenopalatine block|DRUG: Ketoprofen|DRUG: Gabapentin|DRUG: Dexamethasone|DRUG: Theophylline|DIETARY_SUPPLEMENT: Espresso coffee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intratumoral Bromelain + Acetylcysteine in Relapsed and Unresectable Pseudomyxoma Peritonei
Status: UNKNOWN
Conditions: Pseudomyxoma Peritonei
Interventions: DRUG: Bromelin|DRUG: N-Acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Paromomycin to Treat Visceral Leishmaniasis
Status: COMPLETED
Conditions: Visceral Leishmaniasis
Interventions: DRUG: Paromomycin sulfate|DRUG: Amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anticoagulation With Rivaroxaban in Cardioversion -The ARC Study
Status: COMPLETED
Conditions: Atrial Fibrillation|Stroke|Thrombo-embolism|Bleeding
Interventions: DRUG: Rivaroxaban|DRUG: Warfarin and Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study of Multiple Doses of Isavuconazole and Single Dose of Atorvastatin
Status: COMPLETED
Conditions: Pharmacokinetics of Isavuconazole|Pharmacokinetics of Atorvastatin|Healthy Volunteers
Interventions: DRUG: Isavuconazole|DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Study of GDC-0084 in Patients With Progressive or Recurrent High-Grade Glioma
Status: COMPLETED
Conditions: Glioblastoma, Glioma
Interventions: DRUG: GDC-0084
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Iron Pre-treatment in Prognathic Surgery
Status: UNKNOWN
Conditions: Prognathic Surgery
Interventions: DRUG: Ferric carboxymaltose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pyridostigmine (Mestinon) on Muscle Strength in Myasthenia Gravis
Status: UNKNOWN
Conditions: Myasthenia Gravis
Interventions: DRUG: Pyridostigmine|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Bimekizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of TEV-48125 (Fremanezumab) for the Prevention of Episodic Cluster Headache (ECH)
Status: TERMINATED
Conditions: Episodic Cluster Headache
Interventions: DRUG: Fremanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D After Application With Valchlor
Status: COMPLETED
Conditions: Skin Irritation
Interventions: DIETARY_SUPPLEMENT: 4 placebo|DIETARY_SUPPLEMENT: 4 Vitamin D|DRUG: Valchlor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Brivaracetam to Reduce Neuropathic Pain in Chronic SCI: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Status: RECRUITING
Conditions: Spinal Cord Injuries|Neuropathic Pain
Interventions: DRUG: brivaracetam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PV Reconnection After PVAI at Different Power Settings and Adenosine Provocation
Status: UNKNOWN
Conditions: Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: PVAI followed by adenosine provocation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Near InfraRed Fluorescence Using Indocyanine Green and Magnetic Resonance Lymphography of Lymphatic Transport
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Indocyanine Green|DEVICE: MultiSpectral Imaging System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized Clinical Trial of a Novel Drug Education and Diversion Program (iDECIDE) for Middle and High School Students
Status: RECRUITING
Conditions: Substance Use|Harm Reduction|Adolescent Behavior
Interventions: BEHAVIORAL: iDECIDE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Determine the Maximum Tolerated Dose (MTD) of BIBF 1120 in Patients With Solid Tumours
Status: COMPLETED
Conditions: Malignant Solid Tumour
Interventions: DRUG: BIBF 1120
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Addition of Zinc to the Current Case Management Package of Diarrhea in a Primary Health Care Setting
Status: COMPLETED
Conditions: Diarrhea|Mortality|Hospitalization
Interventions: DRUG: Zinc and ORS|DRUG: ORS only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT