pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Drug-Eluting Bead, Irinotecan (DEBIRI) Therapy of Liver Metastasis From Colon Cancer With Systemic Fluorouracil, Oxaliplatin, Leucovorin and Bevacizumab
Status: COMPLETED
Conditions: Colon Cancer With Metastases to the Liver
Interventions: DEVICE: LC beads loaded with Irinotecan|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: 5-Fluorouracil|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: H-22411: BOTOX® for Peyronie's Disease
Status: COMPLETED
Conditions: Peyronie's Disease
Interventions: DRUG: 100 units of Botulinum Toxin Type A|OTHER: Preservative free normal saline|DRUG: 100 units Botulinum Toxin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VEGF Receptor Tyrosine Kinase Inhibitor Axitinib in Children With Recurrent or Refractory Solid Tumors
Status: COMPLETED
Conditions: Refractory or Recurrent Solid Tumors, Excluding CNS Tumors
Interventions: DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 6-Month Open-Label Safety Study Of PD 0332334 In Elderly Patients With Generalized Anxiety Disorder (GAD)
Status: WITHDRAWN
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: PD-0332334
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Teaching Healthy Responsive Parenting During Infancy to Promote Vital Growth and dEvelopment (THRIVE) Study
Status: COMPLETED
Conditions: Parenting|Feeding Behavior|Sleep|Parent-Child Relations
Interventions: BEHAVIORAL: THRIVE intervention|BEHAVIORAL: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Relative Bioavailability and Food Effect Study With Vericiguat to Characterize the Pediatric Formulation in Adult Healthy Subjects
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Vericiguat(BAY1021189, high-dose pediatric-formulation)_fed|DRUG: Vericiguat(BAY1021189, high-dose pediatric-formulation)_fasted|DRUG: Vericiguat(BAY1021189, low-dose pediatric-formulation)_fed|DRUG: Vericiguat(BAY1021189,10 mg IR film-coated tablets,intact)_fed;American breakfast|DRUG: Vericiguat(BAY1021189,10 mg IR film-coated tablets,crushed)_fed;American breakfast|DRUG: Vericiguat(BAY1021189,10 mg IR film-coated tablets,intact)_fed;Continental breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Embryo Development Using Two Commercial Single-step Media
Status: COMPLETED
Conditions: Infertility
Interventions: OTHER: embryo culture in different single-step media
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Temozolomide and Radiation Therapy in Treating Patients With Brain Metastasis Secondary to Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer|Metastatic Cancer
Interventions: DRUG: Temozolomide|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin and Imatinib in Patients With Relapsed or Refractory ALK+ ALCL
Status: TERMINATED
Conditions: ALK+ Anaplastic Large Cell Lymphoma
Interventions: DRUG: Brentuximab vedotin|DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrapulmonary Percussive Ventilation (IPV) Versus Nasal Continuous Positive Airway Pressure Ventilation (nCPAP) in Transient Respiratory Distress of the Newborn
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Newborn
Interventions: PROCEDURE: Nasal Continuous Positive Airway Pressure ventilation|PROCEDURE: Intrapulmonary Percussive Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electroacupuncture for Tapering Off Long-term Benzodiazepine Use
Status: UNKNOWN
Conditions: Benzodiazepine Dependence
Interventions: DEVICE: Electroacupuncture|DEVICE: Placebo acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Injection in Patients With Chronic Shoulder Pain
Status: COMPLETED
Conditions: Chronic Shoulder Pain
Interventions: OTHER: Suprascapular nerve block with physical therapy|OTHER: Group 2 Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Women With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Detox-B adjuvant|BIOLOGICAL: THERATOPE STn-KLH vaccine|BIOLOGICAL: keyhole limpet hemocyanin|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Celecoxib Versus Placebo Before and After Knee Surgery on Overall Use of Analgesics After Surgery
Status: COMPLETED
Conditions: Arthroscopy
Interventions: OTHER: Placebo|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Reduction Ratio and Clearance During Hemodialysis With MCO-filter Compared to HDF With Standard High-flux Filter
Status: COMPLETED
Conditions: Chronic Kidney Failure|Uremia|Dialysis
Interventions: DEVICE: MCO-HD|DEVICE: High-flux HDF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib/II Study of the Safety and Immunogenicity of the Candidate Rabies Vaccine ChAdOx2 RabG
Status: ACTIVE_NOT_RECRUITING
Conditions: Rabies
Interventions: BIOLOGICAL: ChAdOx2 RabG|BIOLOGICAL: Inactivated Rabies Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concomitant Use of Apremilast for the Treatment of Active RA Despite TNF-Inhibition and Methotrexate- CATARA
Status: WITHDRAWN
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Apremilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Facial Flushing With Botulinum Toxin A Injections
Status: ACTIVE_NOT_RECRUITING
Conditions: Facial Flushing
Interventions: DRUG: botulinum toxin A|OTHER: Saline Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Appethyl® vs Placebo on Human Health (Appethyl)
Status: TERMINATED
Conditions: Overweight and Obesity|PreDiabetes
Interventions: DIETARY_SUPPLEMENT: Appethyl®|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dalfampridine in Egyptian Patients With Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: DRUG: Dalfampridine ER, 10 Mg Oral Tablet, Extended Release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROMISE II: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Critical Limb Ischemia|Critical Lower Limb Ischemia|Peripheral Artery Disease|Peripheral Arterial Disease|Chronic Limb-Threatening Ischemia|Arterial Occlusive Diseases|Arterial Occlusion|Arterial Disease|Peripheral Artery Occlusion|Peripheral Vascular Disease|Peripheral Ischemia|Vascular Diseases
Interventions: DEVICE: LimFlow System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing Evidence Based Treatment of Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Patient educational letter to engage provider in hypertension rx discussion|BEHAVIORAL: Financial incentive (Arms B and C) and health educator phone call (Arm C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polyphenol Rich Aerosol as a Support for Cancer Patients in Minimizing Side Effects After a Radiation Therapy
Status: RECRUITING
Conditions: Oral Mucositis
Interventions: DIETARY_SUPPLEMENT: Aerosol (Polyphenol-rich plant extracts, Hyaluronic Acid, Cetraria Islandica, Vitamin B3)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Subunit Vaccine Against Herpes Zoster in RA Patients Treated With JAK-inhibitors (VACCIMIL-ZOSTER)
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Healthy Controls
Interventions: BIOLOGICAL: Shingrix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Relative Bioavailability Study of a Pediatric Granule Formulation of Dolutegravir
Status: COMPLETED
Conditions: Infections, Human Immunodeficiency Virus and Herpesviridae
Interventions: DRUG: Dolutegravir 50 mg tablet|DRUG: Dolutegravir 50 mg oral granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Mediterranean Lifestyle Intervention in Patients With Non-alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease (NAFLD)|Non-alcoholic Steatohepatitis (NASH)
Interventions: BEHAVIORAL: Mediterranean lifestyle|BEHAVIORAL: Mediterranean Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Designed to Determine the Safety and Pharmacological Response ofMKC253 Inhalation Powder in Adults With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: MKC253 Inhalation Powder|DRUG: Technosphere Inhalation Powder|DRUG: subcutaneous injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Levamisole for Maintaining Remission After the First Flare of Steroid Sensitive Nephrotic Syndrome in Children
Status: COMPLETED
Conditions: First Manifestation of Steroid Sensitive Nephrotic Syndrome
Interventions: DRUG: Levamisole Hydrochloride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Rituximab on Immunological Recall Response to Specific Antigens in the Treatment of Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Patient Education Via Animated Videos to Improve Patient Satisfaction and Reduce Complications in Head and Neck Surgery
Status: COMPLETED
Conditions: Patient Satisfaction|Surgery
Interventions: OTHER: Precare|OTHER: usual standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamic Effects of MEDI5884 in Adults With Stable Coronary Heart Disease
Status: COMPLETED
Conditions: Stable Coronary Heart Disease
Interventions: DRUG: MEDI5884|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Rosuvastatin on Adenosine Metabolism
Status: COMPLETED
Conditions: Adenosine Metabolism
Interventions: DRUG: placebo|DRUG: rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Controlled Trial to Study the Outcome of Intravenous Phosphate Supplementation in Live Donors Undergoing Hepatectomy for Living Donor Liver Transplantation (LDLT)
Status: COMPLETED
Conditions: Complication, Postoperative|Regeneration Liver
Interventions: DRUG: Potassium Phosphate Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevention of Venous Thromboembolism in Patients Undergoing Elective Total Knee Replacement Surgery
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Semuloparin sodium|DRUG: Placebo (for Enoxaparin sodium)|DRUG: Enoxaparin sodium|DRUG: Placebo (for Semuloparin sodium)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Complications of Gonadal Veins Embolization
Status: UNKNOWN
Conditions: Coil Embolization|Pelvic Venous Disorders|Gonadal Veins Insufficiency|Pelvic Venous Pain
Interventions: PROCEDURE: gonadal vein embolization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Influence of Temperature on Transcutaneous Blood Gas Diffusion: CAPNOS Project
Status: RECRUITING
Conditions: Healthy Volunteers, Pathologies for Which paCO2 Monitoring is Crucial, Particularly in the Context of Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DEVICE: tcpCO2 measure|DEVICE: tcpO2 measure|DEVICE: measurement of tissue conductivity to CO2: KS|DEVICE: measurement of microcirculation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension -AYAME Study-
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Placebo ophthalmic solution|DRUG: DE-117 ophthalmic solution low|DRUG: DE-117 ophthalmic solution high|DRUG: Latanoprost ophthalmic solution 0.005%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ENA-001 for Post Operative Respiratory Depression (PORD)
Status: NOT_YET_RECRUITING
Conditions: Respiratory Depression
Interventions: DRUG: ENA-001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Of Treatment Patterns And Clinical Outcomes In Patients Diagnosed With Acute Myeloid Leukemia Who Received Mylotarg in the Real-World
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Gemtuzumab Ozogamicin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 13 Valent Pneumococcal Conjugate Vaccine in Chronic Dialysis Patients
Status: COMPLETED
Conditions: Chronic Kidney Failure
Interventions: BIOLOGICAL: PPV23 vaccination or PCV13 vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Minimally Invasive Coronary Surgery Compared to STernotomy Coronary Artery Bypass Grafting Trial
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: MICS CABG|PROCEDURE: Conventional CABG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of the Presence of a Pharmacy Technician on the Quality and Cost of Drug Therapy
Status: COMPLETED
Conditions: Hospitalization
Interventions: OTHER: One month of department-wide observation|OTHER: Pharm Tech participates in department
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Bitter, Umami and Sweet Tastants on Food Intake
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: umami|DIETARY_SUPPLEMENT: bitter|DIETARY_SUPPLEMENT: sweet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of PNT2258 for Treatment of Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin's
Interventions: DRUG: PNT2258
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Formula Identification (FID) 114657 in Contact Lens Wearers
Status: COMPLETED
Conditions: Refractive Error
Interventions: DRUG: FID 114657 eye drops (10 ml)|DRUG: Saline control eye drops (15 ml)|DEVICE: Habitual contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Phase 2 Study of Carfilzomib in Relapsed and Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: carfilzomib|DRUG: carfilzomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: How to Act on the Mobility Restriction Linked to Senior's Phobia of Falling
Status: COMPLETED
Conditions: Specific Phobia|Fear of Falling
Interventions: OTHER: Physical activity|OTHER: Home assessment and modification|BEHAVIORAL: Cognitive behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Clinical Effects of Azathioprine and Rituximab NMO-SD Patients
Status: COMPLETED
Conditions: Neuromyelitis Optica Spectrum Disorder
Interventions: DRUG: Azathioprine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beneficial Effects of Magnesium Supplementation On Idiopathic Muscle Cramps
Status: COMPLETED
Conditions: Muscle Cramp
Interventions: DIETARY_SUPPLEMENT: MagTabSR|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intraoperative Nociception Control Based on Analgesia Nociception Index (ANI) Monitoring on Stress Response During Total Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Patients Undergoing Total Laparoscopic Hysterectomy
Interventions: DEVICE: conventional nociception control|DEVICE: ANI monitor guided nociception control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Robot-based Tele-echography II - A Comparative Study
Status: TERMINATED
Conditions: Abdominal Injuries|Thoracic Injuries|High Energy Trauma
Interventions: DEVICE: Robot-Based Tele-Echography (TER)|DEVICE: ultrasound method FAST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Research Study Looking at How Safe it is to Switch From Emicizumab to Mim8 in People With Haemophilia A (FRONTIER 5)
Status: ACTIVE_NOT_RECRUITING
Conditions: Haemophilia A|Haemophilia A With Inhibitors
Interventions: DRUG: NNC0365-3769 (Mim8) PPX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mental Health Associations With Vitiligo
Status: COMPLETED
Conditions: Vitiligo|Depressive Episode|Recurrent Depressive Disorder|Anxiety Disorders|Social Phobia|Adjustment Disorders|Substance Abuse|Self-Harm, Deliberate|Overdose|Suicide, Attempted|Parasuicide
Interventions: OTHER: Exposure of mental health condtion of interest
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Intracerebral Hemorrhage Acutely Decreasing Arterial Pressure Trial II
Status: RECRUITING
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: labetalol/hydralazine/enalapril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome Study of Endoscopically Inserted Gastrostomy (PEG)Versus Radiologically-guided Insertion of Gastrostomy (RIG)in Children
Status: UNKNOWN
Conditions: Two Interventions (PEG and RIG) Compared Against Each Other
Interventions: PROCEDURE: Percutaneous Endoscopic Gastrostomy|PROCEDURE: Radiologically-guided insertion of Gastrostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Addition of Inhaled Furosemide to Standard Treatment of COPD Exacerbation
Status: NOT_YET_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease Exacerbation|COPD Exacerbation
Interventions: DRUG: Furosemide|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intraoperative Injections on Postoperative Pain Control During Total Hip Replacement
Status: WITHDRAWN
Conditions: Osteoarthritis|Degenerative Joint Disease
Interventions: DRUG: Bupivicaine + epinephrine|DRUG: Bupivacaine|DRUG: Ropivacaine|DRUG: Ketorolac|DRUG: Clonidine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of AST-120 Compared to Lactulose in Patients With Hepatic Encephalopathy
Status: COMPLETED
Conditions: Hepatic Encephalopathy
Interventions: DRUG: AST-120|DRUG: lactulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label Safety and Pharmacokinetic Study of INL-001 in Adults Following Various Open Soft-Tissue Surgeries
Status: COMPLETED
Conditions: Pain, Postoperative|Hernia, Ventral|Abdominoplasty|Hysterectomy|Colectomy|Reduction Mammoplasty
Interventions: COMBINATION_PRODUCT: INL-001 (bupivacaine hydrochloride) implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Effects and Neural Mechanisms of Tai Chi and Light-to-Moderate Intensity Aerobic Exercises
Status: UNKNOWN
Conditions: Physical Activity
Interventions: BEHAVIORAL: Tai-Chi exercise|BEHAVIORAL: Aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Dual Impact of Homocysteine and Cholesterol on Cognitive Functions
Status: COMPLETED
Conditions: Hypercholesterolemia|Cognitive Dysfunction|Hyperhomocysteinemia
Interventions: DIAGNOSTIC_TEST: Blood sampling for total cholesterol and homocysteine and cognitive assessment by psychometric tests.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Phosphatidylinositol-3-kinase (PI3K) Inhibitor Idelalisib (GS-1101) in Waldenström Macroglobulinemia
Status: TERMINATED
Conditions: Waldenstrom's Macroglobulinemia
Interventions: DRUG: GS-1101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Fuels Study
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Low carbohydrate diet|BEHAVIORAL: Moderate carbohydrate diet|BEHAVIORAL: High carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dysphagia After Anterior Cervical Spine Surgery
Status: RECRUITING
Conditions: Dysphagia|Cervical Spinal Cord Injury
Interventions: DEVICE: Oral neuromuscular training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Hyperexcitability in AD With Levetiracetam
Status: RECRUITING
Conditions: Alzheimer Dementia|Alzheimer Disease|Dementia of Alzheimer Type|Mild Cognitive Impairment
Interventions: DRUG: Levetiracetam|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Treatment of the Median Nerve for the Elimination of the Symptoms Associated With the Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Compression Neuropathy, Carpal Tunnel
Interventions: PROCEDURE: Ischemic Compression (thumb Pressure)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Two Protocols of re Irradiation in an Irradiated Area for Carcinoma of the Upper Aerodigestive Tract
Status: COMPLETED
Conditions: Squamous Cell Carcinoma
Interventions: RADIATION: single-fraction radiotherapy with concomitant 5FU and Hydrea|RADIATION: hyperfractionated radiotherapy with concomitant Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Cystoid Macular Edema Secondary to Retinitis Pigmentosa Via Subliminal Micropulse Yellow Laser
Status: COMPLETED
Conditions: Retinitis Pigmentosa|Cystoid Macular Edema
Interventions: DEVICE: SL-MPL treatment protocol was performed with a 577 nm yellow laser (EasyRet, Quantel Medical, Cedex, France)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ZL-82 Double-blind Clinical Trial
Status: RECRUITING
Conditions: Healthy Person
Interventions: DRUG: ZL-82|DRUG: ZL-82 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ranolazine for Incomplete Vessel Revascularization Post-Percutaneous Coronary Intervention (PCI)
Status: COMPLETED
Conditions: Coronary Artery Disease|Angina Pectoris
Interventions: DRUG: Ranolazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Conbercept in Refractory Uveitic Macular Edema and VEGF
Status: TERMINATED
Conditions: Uveitis|Macular Edema|Vascular Endothelial Growth Factor|Effect of Drugs
Interventions: DRUG: intravitreal injection of Conbercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating the Change in Metabolism Phenotype in Paediatric, Adolescent & Young Adults With Hodgkin or Non-Hodgkin Lymphoma.
Status: NOT_YET_RECRUITING
Conditions: Hodgkin Lymphoma|Non Hodgkin Lymphoma
Interventions: DRUG: Omeprazole|DRUG: Dextromethorphan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sup-ER Protocol RCT
Status: TERMINATED
Conditions: Birth Related Brachial Plexus Injury|Obstetrical Brachial Plexus Palsy
Interventions: OTHER: Sup-ER Protocol|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Rapid-Acting Mealtime Insulin in Children and Adolescents With Newly Diagnosed Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus|Type 1 Diabetes
Interventions: DRUG: Rapid-Acting Insulin|DRUG: Long acting insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Pharmacodynamics of Edoxaban Before and After Bariatric Surgery
Status: WITHDRAWN
Conditions: Bariatric Surgery Candidate
Interventions: DRUG: Edoxaban Pharmacokinetics and Pharmacodynamics
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Non-Ablative Fractional Resurfacing of Total Knee Replacement Scars
Status: UNKNOWN
Conditions: Epidermal Thickening, Unspecified
Interventions: PROCEDURE: Non-Abilative Laser treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Measurement of Glomerular Filtration Rate (GFR) in HIV Patients: Single-center Study Comparing the Accuracy of Estimators of GFR Versus Iohexol Plasma Clearance
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: iohexol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effect of the Coughing Technique During Subcutaneous Heparin Injection
Status: COMPLETED
Conditions: Thyroidectomy|Colon Surgery|Cholecystectomy|Inguinal Hernia
Interventions: OTHER: the medium intensity coughing technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: XL TDR® eXtreme Lateral Total Disc Replacement for the Treatment of Lumbar Degenerative Disc Disease (DDD)
Status: COMPLETED
Conditions: Degenerative Disc Disease
Interventions: DEVICE: XL TDR|OTHER: Lumbar fusion surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IFN-γ to Treat Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) That Has Relapsed After Allogeneic Hematopoietic Stem Cell Transplantation
Status: COMPLETED
Conditions: Myelodysplastic Syndromes|Myeloid Leukemia|Allogeneic Stem Cell Transplantation
Interventions: DRUG: IFN-γ (interferon gamma-1b) injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study Evaluating Glofitamab in Combination With Gemcitabine + Oxaliplatin vs Rituximab in Combination With Gemcitabine + Oxaliplatin in Participants With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Obinutuzumab|DRUG: Glofitamab|DRUG: Rituxumab|DRUG: Tocilizumab|DRUG: Gemcitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Neurorehabilitation Therapy on Postural Control, Mobility and Quality of Life in Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Multiple Sclerosis, Chronic Progressive|Multiple Sclerosis, Primary Progressive
Interventions: OTHER: Neurorehabilitation|OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing in Dexmedetomidine With po/pr Midazolam for Procedural Sedation in the Pediatric Emergency Department
Status: WITHDRAWN
Conditions: Procedural Anxiety|Emergencies
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy Between Piracetam and Dimenhydrinate in Patients With Peripheral Vertigo
Status: COMPLETED
Conditions: Peripheral Vertigo
Interventions: DRUG: Administration of 100 mg dimenhydrinate intravenous|DRUG: 2 g piracetam intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Physical Training for People With Parkinson's Disease and Multiple Sclerosis: Effect on Mind and Body
Status: RECRUITING
Conditions: Parkinson Disease|Multiple Sclerosis
Interventions: BEHAVIORAL: High Intensity Interval Training (HIIT)|BEHAVIORAL: Continuous Aerobic Training (CAT)|BEHAVIORAL: Movement Advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Zinc L-carnosine in Maintaining Remission of Gastroesophageal Reflux Disease
Status: UNKNOWN
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Zinc-l-carnosine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and Capecitabine for First Line Treatment of Metastatic Squamous Cell Carcinoma of the Head & Neck
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DRUG: Docetaxel|DRUG: Capecitabine|DRUG: Premedication
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Non-Inferiority Study Comparing 3 Weekly Injections of SUPARTZ® vs 3 Weekly Injections of Euflexxa® for Knee OA
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Supartz|DEVICE: Euflexxa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nurse-Led Mobile App Effect on Symptom Management for Breast Cancer Patients After Surgery
Status: COMPLETED
Conditions: Symptom Management|Breast Care Nurse|Mobile App|Mobile Health
Interventions: DEVICE: NL-Mapp
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of Meningococcal Group B Vaccine rMenB+OMV NZ (Bexsero) to Prevent Gonococcal Infection
Status: RECRUITING
Conditions: Gonococcal Infection
Interventions: BIOLOGICAL: Meningococcal Group B Vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study on the Efficacy and Safety of T-02 for the Treatment for Acute Ischemic Stroke
Status: WITHDRAWN
Conditions: Acute Ischemic Stroke|Large Vessel Occlusion|Vascular Occlusion|Thrombosis|Endovascular
Interventions: DEVICE: T-02
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Post Marketing Study in Subjects Who Have Type 2 Diabetes Using the EndoBarrier™ Gastrointestinal Liner
Status: COMPLETED
Conditions: Type 2 Diabetes|Obesity
Interventions: DEVICE: EndoBarrier Gastrointestinal Liner
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ultrasound-guided Lateral Thoracolumbar Interfascial Plane Block (TLIPB) for Postoperative Pain in Patients Undergoing Herniated Lumbar Disc Surgery
Status: UNKNOWN
Conditions: Postoperative Pain|Lumbar Disc Surgery
Interventions: PROCEDURE: PCIA group|PROCEDURE: Lateral TLIPB group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oxytocin on Cold Water Task Performance and Recovery
Status: COMPLETED
Conditions: Cold Exposure
Interventions: DRUG: Oxytocin nasal spray|DRUG: Placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 3D-Conformal Radiation vs Helical Tomotherapy in Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: RADIATION: Arm B: Helical Tomotherapy Intensity Modulated Radiotherapy|OTHER: Arm A: 3D-Conformal Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Engagement in Services for First-Episode Psychosis
Status: RECRUITING
Conditions: Engagement, Patient|First Episode Psychosis
Interventions: BEHAVIORAL: Behavioral Activation for First Episode Psychosis|BEHAVIORAL: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microsurgical Varicocelectomy Versus No Surgery in Men With a Palpable Varicocele and an Abnormal Semen Analysis
Status: TERMINATED
Conditions: Pregnancy|Infertility
Interventions: BEHAVIORAL: Timed intercourse|PROCEDURE: Microsurgical varicocelectomy|PROCEDURE: Intrauterine insemination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Web App With Multimedia Animations to Teach Therapeutic Exercise in Shoulder Pain
Status: UNKNOWN
Conditions: Shoulder Impingement Syndrome
Interventions: BEHAVIORAL: Web app exercises program|BEHAVIORAL: Exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine or Bupivacaine
Status: TERMINATED
Conditions: Anesthesia, Local|Shoulder Surgery
Interventions: DRUG: saline|DRUG: Dexamethasone|DRUG: ropivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Lifestyle Modification on Pregnancy Outcome for GDM
Status: COMPLETED
Conditions: GDM|Lifestyle|Pregnancy Outcome
Interventions: BEHAVIORAL: lifestyle modification (dietary modification)|BEHAVIORAL: lifestyle modification (physical activity)|BEHAVIORAL: lifestyle modification( self glucose monitoring)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Role of Tibial Nerve Stimulation for Enhanced Postoperative Recovery After Colorectal Surgery
Status: COMPLETED
Conditions: Postoperative Ileus|Colorectal Cancer
Interventions: PROCEDURE: Tibial nerve stimulation|PROCEDURE: Sham tibial nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Acceptability and Preference for Contraceptive Options as Proxy for HIV Prevention Methods
Status: UNKNOWN
Conditions: HIV
Interventions: DRUG: Nur-Isterate|DEVICE: Nuvaring|DRUG: Triphasil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Rifampin in CYP24A1-related Hypercalcemia and Hypercalciuria
Status: RECRUITING
Conditions: Idiopathic Infantile Hypercalcaemia - Severe Form|Genetic Disease|Hypercalcemia, Idiopathic, of Infancy|Hypercalciuric Hypercalcemia|Idiopathic Infantile Hypercalcemia - Mild Form|Hypercalciuria
Interventions: DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mitochondrial Effects of C18:0 Supplementation in Humans
Status: COMPLETED
Conditions: Alteration of Mitochondrial Membrane|Type2 Diabetes|Fatty Acid Deficiency
Interventions: DIETARY_SUPPLEMENT: C18:0|DIETARY_SUPPLEMENT: mock
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Bacopa in Gulf War Illness Patients
Status: RECRUITING
Conditions: Gulf War Illness
Interventions: DIETARY_SUPPLEMENT: BacoMind® (Bacopa monnieri standardized extract)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Experimental Drugs ABT- 493/ABT-530 in Adults With Chronic Hepatitis C Virus Genotype 1-6 Infection and Human Immunodeficiency Virus -1 Coinfection (EXPEDITION-2)
Status: COMPLETED
Conditions: Hepatitis C Virus Infection|Human Immunodeficiency Virus Infection|Chronic Hepatitis C|Compensated Cirrhosis and Non-cirrhotics
Interventions: DRUG: ABT-493 coformulated with ABT-530
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Value of eHealth for Bariatric Surgery
Status: UNKNOWN
Conditions: Bariatric Surgery|Obesity|Telemedicine
Interventions: OTHER: Access to online eLearning module|OTHER: Access to measurement devices|PROCEDURE: Conventional group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide in Adolescents
Status: NOT_YET_RECRUITING
Conditions: Obesity|Adolescent Obesity|Body-Weight Trajectory|Weight Loss Trajectory|Bariatric Surgery|Anti-obesity Agents
Interventions: DRUG: Injectable semaglutide|BEHAVIORAL: Usual postoperative care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Mental Imagery for Suicidality in Students Trial (MISST)
Status: COMPLETED
Conditions: Suicide, Attempted|Suicidal Ideation
Interventions: OTHER: Broad-Minded Affective Coping Intervention|OTHER: Risk Assessment and Signposting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Measurement of Insulin Levels in the Cerebrospinal Fluid of Healthy Adults After a Single Intranasal Dose - Middle Age
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: Low Dose Regular insulin|DRUG: High Dose Regular insulin|OTHER: 0.9% Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Clinical Study to Investigate the Efficacy, Safety and Pharmacokinetics of ASP3652 in Patients With Chronic Abacterial Prostatitis / Chronic Pelvic Pain Syndrome (CP/CPPS)
Status: COMPLETED
Conditions: Chronic Abacterial Prostatitis|Chronic Pelvic Pain Syndrome
Interventions: DRUG: ASP3652|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Postoperative Atrial Fibrillation (POAF) Using Intra-Pericardial Amiodarone
Status: RECRUITING
Conditions: Atrial Fibrillation|Post-Op Complication
Interventions: COMBINATION_PRODUCT: CardiaMend in Combination with Amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Mechanomyographic 100 Versus 200 Hz 5 Second Tetanic Fade Ratios During Neuromuscular Block Recovery
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: DEVICE: Isometric Thumb Force (isometric mechanomyography) compared to TOF-Watch SX (acceleromyography)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Pharmacokinetics and Pharmacodynamics of Subcutaneous Versus Intravenous Administration of Bortezomib in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain From Bunionectomy.
Status: COMPLETED
Conditions: Arthralgia|Bunion|Hallux Valgus|Pain
Interventions: DRUG: Tapentadol (CG5503)|DRUG: Tapentadol (CG5503)|DRUG: oxycodone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Safety and Efficacy in the Use of Hormonal Therapy on Endometriosis Patients After Conservative Surgery
Status: RECRUITING
Conditions: Endometriosis Ovary
Interventions: DRUG: Dienogest|DRUG: Depo Medroxyprogesterone acetate|DRUG: Leuprolide (as Leuprolide Acetate)|DRUG: Levonogestrel + etinilestradiol (30 mcg, brand name Mycrogynon)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT