pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: FOLFIRINOX in Patients With Inoperable Pancreatic Cancer
Status: TERMINATED
Conditions: Adenocarcinoma of Pancreas
Interventions: DRUG: Irinotecan, Oxaliplatin, Leucovorin, 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain After Dental Post Application
Status: COMPLETED
Conditions: Postoperative Pain|Endodontically Treated Teeth|Vibration; Exposure
Interventions: PROCEDURE: Group 1: single-visit RCT|PROCEDURE: Group 2: two-visit RCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effects of MDMA and Methylphenidate on Social Cognition
Status: COMPLETED
Conditions: Social Cognition
Interventions: DRUG: 3,4-Methylenedioxymethamphetamine|DRUG: Methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prolonged Exposure (PE) Treatment for Post Traumatic Stress Disorder (PTSD) 20 Minutes Versus 40 Minutes
Status: COMPLETED
Conditions: PTSD
Interventions: BEHAVIORAL: Prolonged Exposure (PE) therapy|BEHAVIORAL: Prolonged Exposure (PE) therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Maintenance Effect of Enstilar Foam in Combination With Otezla
Status: UNKNOWN
Conditions: Psoriasis
Interventions: DRUG: Apremilast 30mg|DRUG: calcipotriene and betamethasone dipropionate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-alcoholic Fatty Liver Disease and Its Treatment
Status: COMPLETED
Conditions: NAFLD
Interventions: DRUG: sitagliptin and metformin|DRUG: Sitagliptin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D to Reduce Colds and Asthma Attacks in Young Children
Status: COMPLETED
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: daily vitamin D supplement|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clamshells Exercise and Vastrus Medialis Oblique Strengthening Exercise on Patellofemoral Pain Syndrome
Status: RECRUITING
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Standard clamshells method|OTHER: Targeted VMO strengthening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Good Start to Life - an Early Cross-sectorial Intervention
Status: COMPLETED
Conditions: Anxiety|Attachment Disorder|Maternal Sensitivity|Depression|Personality Disorders
Interventions: BEHAVIORAL: Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Apalutamide (Adjuvant Treatment) and Androgen Deprivation Therapy (ADT) in Participants Who Have Undergone Radical Prostatectomy (RP) for Non-metastatic Prostate Cancer and Who Are at High Risk for Metastases
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Apalutamide|DRUG: ADT|DRUG: Relugolix
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Self-help Coping App on Distress Levels in Men Experiencing Infertility
Status: UNKNOWN
Conditions: Stress Reduction
Interventions: BEHAVIORAL: FertiStrong App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MED Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Intravenous WCK 5222 (Zidebactam and Cefepime) in Healthy Volunteers
Status: COMPLETED
Conditions: Serious Gram-negative Infections
Interventions: DRUG: Intravenous infusions of WCK 5222|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Primary Vaccination Study With a Pneumococcal Conjugate Vaccine in Healthy Children 6 to 8 Weeks of Age
Status: COMPLETED
Conditions: Infections, Rotavirus
Interventions: BIOLOGICAL: Synflorix|BIOLOGICAL: Infanrix hexa|BIOLOGICAL: Rotarix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Ginger Supplementation on NF-KB in Peripheral Blood Mononuclear Cells in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Ginger|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Amyotrophic Lateral Sclerosis Non-invasive Ventilation Exchange
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: OTHER: Telerehabilitation solution (m-Rehab)|OTHER: Usual management including NIV.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effects of Vildagliptin on Gastric Emptying in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study on Intermittent Ibrutinib in Patients With Advanced-phase Chronic Lymphocytic Leukemia (CLL)
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guideline-Directed Medical Therapy in Patients After Implantation of Implantable Cardioverter Defibrillators to Improve Long-Term Outcomes
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure|ICD
Interventions: OTHER: Specialized heart function clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Live Music Therapy to Reduce Anxiety, Pain and Improve Sleep in Post-Operative Lung Transplant Patients: A Pilot Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Transplant; Complications
Interventions: BEHAVIORAL: Music Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Subretinally Injected ATSN-101 Administered in Patients With Leber Congenital Amaurosis Caused by Biallelic Mutations in GUCY2D
Status: ACTIVE_NOT_RECRUITING
Conditions: Leber Congenital Amaurosis|LCA|LCA1
Interventions: DRUG: ATSN-101|DRUG: ATSN-101 Diluent Solution|DRUG: Prednisone|DRUG: Triamcinalone Acetonide|DRUG: 1% Prednisolone|DRUG: Trimethoprim/polymyxin B
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of the PXL Platinum 330 System With Riboflavin Solution for Previously Untreated Corneal Ulcers
Status: UNKNOWN
Conditions: Keratitis|Corneal Ulcer
Interventions: COMBINATION_PRODUCT: Standard of Care Therapy + CXL + Riboflavin 0.23% L Solution|OTHER: Standard of Care Therapy + Sham CXL + Artificial Tears
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness to Enhance Quality of Life and Support Advance Care Planning
Status: COMPLETED
Conditions: Mindfulness|Meditation|Metastatic Cancer|Quality of Life|Advance Care Planning|Palliative Care|Family Caregiver|Supportive Care
Interventions: BEHAVIORAL: Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Oral Encochleated Amphotericin B (CAMB/MAT2203) in the Treatment of Vulvovaginal Candidiasis (VVC)
Status: COMPLETED
Conditions: Vulvovaginitis|Yeast Infection|Yeast Infection Vaginal|Candidiasis, Vulvovaginal
Interventions: DRUG: Oral Encochleated Amphotericin B (CAMB)|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MSC and Cyclophosphamide for Acute Graft-Versus-Host Disease (aGVHD) Prophylaxis
Status: UNKNOWN
Conditions: Leukemia|Multiple Myeloma
Interventions: DRUG: Cyclophosphamide|BIOLOGICAL: Mesenchymal stromal cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of MgSO4 for Pain After Bariatric Surgery
Status: COMPLETED
Conditions: Therapeutic Opioid Induced Constipation (Disorder)
Interventions: DRUG: Magnesium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Decompression and Drainage Seton in the Treatment of High Complex Anal Fistula
Status: COMPLETED
Conditions: High Complex Anal Fistula
Interventions: PROCEDURE: Decomprssion and drainage seton|PROCEDURE: Cutting seton
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Central and Peripheral Nervous System Changes as Markers of Disease Progression in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Neurodegeneration|Central Nervous System Lesion|Peripheral Nervous System Problem|Neurologic Deficits|Drug Effect|Genetic Disease|Neurophysiologic Abnormality
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Irinotecan, Cisplatin and Celebrex in Patients With Metastatic or Unresectable Esophageal Cancer
Status: TERMINATED
Conditions: Esophageal Cancer
Interventions: DRUG: irinotecan, cisplatin, celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HD-Idarubicin/Etoposide Intensified Conditioning Regimen Allo-HSCT for Adult ALL
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: IDA|RADIATION: TBI|DRUG: CTX|DRUG: VP-16
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lercanidipine and Enalapril in Patients With Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Placebo|DRUG: Lercanidipine|DRUG: Lercanidipine|DRUG: Enalapril|DRUG: Enalapril|DRUG: Lercanidipine + Enalapril|DRUG: Lercanidipine + Enalapril|DRUG: Lercanidipine + Enalapril|DRUG: Lercanidipine + Enalapril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rewards for Cannabis Abstinence-study
Status: RECRUITING
Conditions: Cannabis Use Disorder
Interventions: BEHAVIORAL: Abstinence-focused Contingency Management (CM) - stand alone|BEHAVIORAL: Standard Outpatient Cognitive Behavioural Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Looking at Novel Scheduling of Cabazitaxel for Patients With Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Castration Resistant Prostate Cancer
Interventions: DRUG: Cabazitaxel|DRUG: weekly cabazitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatic Safety of Raltegravir Versus Efavirenz as HIV Therapy for Patients With HIV and HCV Coinfection
Status: COMPLETED
Conditions: Hepatitis C, Chronic|HIV Infection
Interventions: DRUG: Raltegravir|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: H-reflex Responses to High-Velocity Low-Amplitude Manipulation
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: HVLA manipulation|OTHER: Sham Spinal lumbar manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome|Recurrent Acute Myeloid Leukemia|Recurrent Myelodysplastic Syndrome|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Decitabine|DRUG: Quizartinib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Short-Course Antimicrobial Treatment for Children With Acute Otitis Media and Impact on Resistance
Status: TERMINATED
Conditions: Acute Otitis Media
Interventions: DRUG: Amoxicillin-Clavulanate, 10 days|DRUG: Amoxicillin-Clavulanate, 5 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retrospective Study Evaluating IGF1R And p95HER2 as Prognostic Factors in Non Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: GENETIC: Protein expression by immunohistochemistry and immunofluorescence
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial to Evaluate Effectiveness of a Probiotic Preparation Administered to Patients With Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DIETARY_SUPPLEMENT: Probiotic mixture|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Assessment of Curcuma Longa Potentials for Soft and Hard Tissue Healing in Fresh
Status: RECRUITING
Conditions: Tooth Extraction Status Nos|Tooth Fracture
Interventions: BIOLOGICAL: PRF|BIOLOGICAL: Curcuma Longa gel|OTHER: extraction socket
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Anticoagulation Therapy in Hemodialysis Patients With Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|End Stage Renal Disease
Interventions: DRUG: apixaban|DRUG: warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ivermectin in Adults With Severe COVID-19.
Status: TERMINATED
Conditions: Covid19|Severe Acute Respiratory Syndrome
Interventions: DRUG: Ivermectin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ozone Therapy for Lumbar Herniated Disc
Status: TERMINATED
Conditions: Lumbar Herniated Disc
Interventions: PROCEDURE: Discectomy/ micro discectomy|DRUG: Ozone therapy|DRUG: Oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Saxagliptin + Metformin Compared to Saxagliptin or Metformin Monotherapy in PCOS Women With Impaired Glucose Homeostasis
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Disorder of Glucose Regulation
Interventions: DRUG: Metformin XR|DRUG: Saxagliptin|DRUG: Saxagliptin-Metformin XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Efficacy and Safety of Defibrotide vs Best Supportive Care in the Prevention of Hepatic Veno-Occlusive Disease in Adult and Pediatric Patients
Status: COMPLETED
Conditions: Veno-occlusive Disease
Interventions: DRUG: Defibrotide|OTHER: Best Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Drug-Drug Interaction Study to Evaluate the Effect of PF-06865571 on Metformin Pharmacokinetics
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Metformin|DRUG: PF-06865571
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Dose Escalation Study of Adavosertib(MK1775) in Combination With 5-FU or 5-FU/CDDP in Patients With Advanced Solid Tumor (1775-005
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: adavosertib 20 mg|DRUG: 5-FU 1000 mg/m^2/day|DRUG: CDDP|DRUG: adavosertib 65 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patisiran in Patients With Hereditary Transthyretin-mediated Amyloidosis (hATTR Amyloidosis) Disease Progression Post-Liver Transplant
Status: COMPLETED
Conditions: Amyloidosis, Familial|Transthyretin Amyloidosis
Interventions: DRUG: Patisiran
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Differing Completion Rates of DIABETES Education on Patient Reported Outcomes
Status: ENROLLING_BY_INVITATION
Conditions: Diabetes Mellitus, Type 2|Patient Education as Topic
Interventions: BEHAVIORAL: Type 2 Live Well (structured diabetes self management education programme)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tezosentan in Acute Heart Failure
Status: COMPLETED
Conditions: Acute Heart Failure|Acute Decompensation of Chronic Heart Failure|New Onset of Heart Failure
Interventions: DRUG: tezosentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Drugs BCD-033 and Rebif for Treatment of Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: BCD-033 (interferon beta 1a)|DRUG: Rebif (interferon beta 1a)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Open Ended Trocar vs. Fenestrated Blunt Trocar in Bone Marrow Aspirate for Osteoarthritis
Status: TERMINATED
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: BMA cell therapy injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Purpose of the Study is to Examine Whether Iron Deficiency Anemia is Associated With Increased Production of Thrombin and Whether Correction of Anemia by Providing Iron Intravenously Causes a Significant Reduction in Production of Thrombin.
Status: COMPLETED
Conditions: Iron Deficiency Anemias
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preoperative Ondansetron Lozenge for Prevention of Post-Spinal Shivering in Caesarean Section
Status: RECRUITING
Conditions: Ondansetron Lozenge|Post-Spinal Shivering|Cesarean Section
Interventions: DRUG: Ondansetron lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Influence of Daily Grapes Intake on Sarcopenia in Postmenopausal Women
Status: RECRUITING
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Grape powder supplementation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of the Eko Digital Stethoscope in Capturing Infant ECGs
Status: NOT_YET_RECRUITING
Conditions: Tachyarrhythmia
Interventions: DEVICE: Eko Duo electronic stethoscope|DEVICE: CORE 500 electronic stethoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Electroacupuncture as an Adjunct to Non-Surgical Periodontal Therapy
Status: COMPLETED
Conditions: Periodontal Diseases|Periodontal Inflammation|Periodontitis|Acupuncture|Electroacupuncture|Periodontal Pocket
Interventions: PROCEDURE: Electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate VX-787 Given to Adult Volunteers Inoculated With Live Influenza Virus
Status: COMPLETED
Conditions: Influenza Virus
Interventions: DRUG: VX-787|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IL-2 Signaling and Polarization of Regulatory LBs: Involvement in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: Blood sampling|BIOLOGICAL: CSF sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Extension Study of Zemaira® i.v. Administration in Subjects With Emphysema Due to alpha1-proteinase Inhibitor Deficiency.
Status: COMPLETED
Conditions: Emphysema|Alpha 1-proteinase Inhibitor Deficiency
Interventions: BIOLOGICAL: Alpha1- proteinase inhibitor [human]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Two Stent on the Degree of Early Stent Healing and Late Lumen Loss.The OCT-ORION Study
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Resolute Integrity Stent|DEVICE: Biomatrix stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-FLT3 CAR T-cell Therapy in FLT3 Positive Relapsed/Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: anti-FLT3 CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ASTRAL- a Clinical Study to Assess the Efficacy and Toxicity of High-dose Chemotherapy
Status: COMPLETED
Conditions: Aggressive Non-hodgkin Lymphoma (aNHL)|Lymphoma, B-Cell|Lymphoma, T-Cell
Interventions: DRUG: High dose chemotherapy before allogeneic stem cell transplantation (alloSCT)|PROCEDURE: Bone marrow histology|DIAGNOSTIC_TEST: clinical and laboratory parameters|DIAGNOSTIC_TEST: PET-CT or CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Combination of Anlotinib and Immune Checkpoint Inhibitors for Advanced NSCLC Patients With Muti-line Therapy
Status: COMPLETED
Conditions: NSCLC|Angiogenesis|Immunotherapy
Interventions: DRUG: Anlotinib in combination with Immune checkpoint inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Vitamin C Combined With Metformin in the Treatment of Malignant Tumors
Status: RECRUITING
Conditions: Hepatocellular Cancer|Pancreatic Cancer|Gastric Cancer|Colorectal Cancer
Interventions: DRUG: Vitamin C|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy/Safety of Imprime PGG® Injection With Bevacizumab and Paclitaxel/Carboplatin in Patients With Untreated Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: BIOLOGICAL: Imprime PGG® Injection|BIOLOGICAL: Bevacizumab|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Trazodone on Sleep Apnea Severity
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DRUG: Placebo pill|DRUG: Trazodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pain as Indication for Operative Treatment of Traumatic Rib Fractures
Status: WITHDRAWN
Conditions: Trauma|Rib Fractures|Surgery|Pain
Interventions: DRUG: NSAID|PROCEDURE: thoracic epidural anesthesia|DRUG: opioids|DRUG: paracetamol|PROCEDURE: operative fixation of rib fractures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Safety and Effectiveness Study of the 500 Hz Technolas Perfect Vision Excimer Laser in Asian Eyes Using LASIK
Status: UNKNOWN
Conditions: Myopia|Hyperopia|Presbyopia
Interventions: DEVICE: Proscan, Zyoptix and Supracor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sensory and Cognitive Predictions, and Their Disruptions in Schizophrenia
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia|Sensory Processing Disorder
Interventions: BEHAVIORAL: Illusion task
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact of the Glycaemic Index (GI) on Daily Blood Glucose Profiles and Food Intake in Young Chinese Adult Males
Status: COMPLETED
Conditions: Type 2 Diabetes|Obesity|Prediabetes
Interventions: OTHER: Rice and bread (high GI)|OTHER: Rice and bread (low GI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Phase IIA Study of the HDAC Inhibitor ITF2357 in Patients With JAK-2 V617F Positive Chronic Myeloproliferative Diseases
Status: COMPLETED
Conditions: Myeloproliferative Diseases
Interventions: DRUG: ITF2357
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epigenetic Integrity of Spermatozoa in Patients With Germinal Testicular Tumours
Status: UNKNOWN
Conditions: Seminomas
Interventions: OTHER: Extraction genomic DNA|OTHER: Analysis of methylation profiles of numerous GSI and TE|OTHER: Analysis of methylation for the whole genome (sub-population of 15 samples from group 1)|OTHER: Method of protein detection by immunostaining and flow cytometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lattice Radiotherapy for Dose-Escalated Palliation of Bulky Tumors
Status: RECRUITING
Conditions: Cancer|Metastatic Cancer|Locally Advanced|Locally Advanced Solid Tumor|Locally Advanced Carcinoma
Interventions: RADIATION: Lattice therapy (LRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Dietary Supplementation With Lactobacilllus Reuteri DSM 17938 on Functional Abdominal Pain (FAP) in Children
Status: COMPLETED
Conditions: Functional Abdominal Pain (FAP) in Children
Interventions: DIETARY_SUPPLEMENT: L. reuteri DSM 17938 chewable tablets|DIETARY_SUPPLEMENT: Placebo chewable tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of the Effectiveness of AQ/AS, SP/AQ and SP/CQ for Uncomplicated Malaria in Gambian Children
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Amodiaquine plus artesunate (AQ/AS)|DRUG: Sulfadoxine-pyrimethamine plus chloroquine (SP/CQ)|DRUG: Sulfadoxine-pyrimethamine plus amodiaquine (SP/AQ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Theobromine Toothpaste
Status: COMPLETED
Conditions: Dental Plaque|Dental Care
Interventions: OTHER: Evaluation of the effectiveness of low- fluoridated toothpaste.|OTHER: Evaluation of the effectiveness of fluoridated toothpaste.|OTHER: Evaluation of the effectiveness of theobromine toothpaste (2%) toothpaste.|OTHER: Evaluation of the effectiveness of theobromine toothpaste(4%) toothpaste.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Single and Multiple Ascending Dose Study Assessing the Safety, Tolerability, PK and PD of AG10
Status: COMPLETED
Conditions: Amyloid Cardiomyopathy, Transthyretin-Related
Interventions: DRUG: AG10 oral tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison on Succinylcholine Onset Time Assessed by Train of Four Stimulation Versus Clinical Judgment During Rapid Sequence Induction of Anesthesia
Status: UNKNOWN
Conditions: Suxamethonium Sensitivity|Aspiration of Gastric Contents Into Respiratory Tract, Part Unspecified
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Determine the Best Way to Measure How Quickly the Drug Can Give Relief From Sudden Diarrhea
Status: COMPLETED
Conditions: Diarrhea
Interventions: DRUG: loperamide-simethicone|DRUG: matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Durvalumab Combined With S-1 as Adjuvant Therapy of Resectable BTC
Status: ACTIVE_NOT_RECRUITING
Conditions: Biliary Tract Cancer
Interventions: DRUG: Durvalumab combined with S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Evaluate Effects of VX-661/Ivacaftor on Lung and Extrapulmonary Systems in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Tezacaftor/Ivacaftor|DRUG: Ivacaftor|DRUG: Tezacaftor/Ivacaftor matching placebo|DRUG: Ivacaftor matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The DETOURS Trial: De-escalating Empiric Treatment: Opting Out of Rx for Selected Patients With Suspected Sepsis - Opt-Out Protocol Trial
Status: COMPLETED
Conditions: Antibiotic Stewardship
Interventions: OTHER: Opt-Out Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intravenous Sedation Versus General Anesthesia in Patients Undergoing Minor Gynecologic Surgery
Status: TERMINATED
Conditions: Surgery|Anesthesia|Pain
Interventions: PROCEDURE: General Anesthesia|PROCEDURE: Deep Sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Specific Lp(a) Apheresis for Regression of Coronary and Carotid Atherosclerosis
Status: COMPLETED
Conditions: Atherosclerosis|Coronary Disease|Carotid Artery Diseases
Interventions: PROCEDURE: Specific Lp(a) apheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adductor Canal Block and IPACK Block vs. Isolated Adductor Canal Block for Post-Operative Analgesia Following ACL Reconstruction With Bone Patellar Tendon Bone Autograft:
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Rupture
Interventions: DRUG: IPACK block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on Alzheimer Disease, Presbycusis and Hearing Aids
Status: COMPLETED
Conditions: Alzheimer Disease|Presbycusis
Interventions: DEVICE: Hearing aids used : PHONAK Savia and Valeo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Golf Instruction Versus Tai Chi for People With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Movement Disorders|Neuro-Degenerative Disease
Interventions: OTHER: Golf Instruction|OTHER: Tai Chi Class
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sterotactic Operation Integrating With Thrombolysis in Basal Ganglion Hemorrhage Evacuation
Status: UNKNOWN
Conditions: Basal Ganglia Haematoma
Interventions: PROCEDURE: stereotactic surgery plus thrombolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Hemiplegic Shoulder Pain
Status: COMPLETED
Conditions: Shoulder Pain in Hemiplegic Side After Stroke
Interventions: PROCEDURE: acupuncture|PROCEDURE: TENS|PROCEDURE: sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Outcomes of the Nanoscopic Partial Meniscectomy Versus Standard Arthroscopic Partial Meniscectomy
Status: RECRUITING
Conditions: Meniscus Tear
Interventions: PROCEDURE: Nanoscopic partial meniscectomy|PROCEDURE: Standard Partial Meniscectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial to Assess the Safety, Tolerability and Pharmacokinetics of MDT-637 in Subjects With Intermittent, or Mild-to-Moderate Persistent, Asthma
Status: COMPLETED
Conditions: Drug Safety
Interventions: DRUG: MDT-637|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SUBLIVAC FIX Birch Phase III Short-term Efficacy
Status: COMPLETED
Conditions: Birch Pollen Induced Rhinitis/Rhinoconjunctivitis
Interventions: DRUG: SUBLIVAC FIX Birch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing Saxagliptin Treatment in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Saxagliptin|DRUG: Placebo|DRUG: Metformin (blinded)|DRUG: Metformin (open-label)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Sodium's Effect on Urinary Sodium and Dopamine Excretion in Patients With Postural Tachycardia Syndrome
Status: COMPLETED
Conditions: Postural Orthostatic Tachycardia Syndrome
Interventions: RADIATION: Plasma Volume|PROCEDURE: Exercise Capacity Test - Bicycle|PROCEDURE: Posture Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: "Effects of Manual Lymphatic Drainage in the Neck in Healthy Subjects. Experimental Randomized Crossover Study"
Status: COMPLETED
Conditions: Blood Pressure|Nervous System Diseases, Sympathetic|Heart Rate Low|Lymphatic Diseases
Interventions: OTHER: cervical stimuli|OTHER: terminus|OTHER: Placebo|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neurodynamic Sequencing in Patients With Carpal Tunnel Syndrome
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Neurodynamic Slider Technique from Proximal to Distal|OTHER: Neurodynamic Slider Technique from Distal to Proximal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational,Prospective Natural History Study of Early-Onset Extreme Obesity Due to Bi-Allelic Loss-of-Function Mutations in the POMC, PCSK1 or LEPR Genes
Status: COMPLETED
Conditions: POMC Deficiency Obesity|PCSK1 Deficiency Obesity|LEPR Deficiency Obesity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Short Duration Blood Flow Restriction Training on Musculoskeletal and Performance Outcomes
Status: NOT_YET_RECRUITING
Conditions: Blood Flow Restriction Training
Interventions: OTHER: High Frequency Blood Flow Restriction Training Group|OTHER: Low Frequency Blood Flow Restriction Training Group|OTHER: High Frequency Blood Flow Restriction Training Instability Group|OTHER: Low Frequency Blood Flow Restriction Training Instability Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of T2, T3 Sympathectomy for Postmastectomy Pain Syndrome by Pulse Oximeter
Status: RECRUITING
Conditions: Analgesia
Interventions: PROCEDURE: Thermal Radiofrequency|PROCEDURE: Chemical Neurolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Morphine Versus Epidural Extended Release Morphine for Pediatric Patients Undergoing Spinal Fusion
Status: COMPLETED
Conditions: Pain Management|Spinal Fusion|Scoliosis
Interventions: DRUG: Intrathecal morphine|DRUG: Extended Release Epidural Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Cardiac Sparing in Fetal Hypoxia
Status: COMPLETED
Conditions: Fetal Hypoxia
Interventions: RADIATION: Ultrasound|RADIATION: Doppler ultrasound|RADIATION: Fetal echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Accuracy of Rhythm Detection by a Wearable Smart Watch for Cardiac Arrhythmias (The WATCH-RHYTHM Study)
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: OTHER: AFib detection with wearable smart watch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cadonilimab Combined With Fruquintinib and SBRT as Athird-line and Posterior Line Treatment in Patients With MSS CRC
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Fruquintinib|DRUG: Cadonilimab|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Perioperative Intravenous Magnesium Affect Postoperative Quality of Recovery in Craniotomy Surgery Patients?
Status: NOT_YET_RECRUITING
Conditions: Brain Tumor|Surgery
Interventions: DRUG: IV magnesium sulfate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Observation in Patients With Diffuse Large B-Cell Non-Hodgkin's Lymphoma Treated on Clinical Trial CAN-NCIC-LY9
Status: UNKNOWN
Conditions: Long-term Effects Secondary to Cancer Therapy in Adults|Lymphoma
Interventions: OTHER: clinical observation|PROCEDURE: management of therapy complications
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Omega-3 on Lipid Profile and Serum Leptin Level n Neonates With Intrauterine Growth Restriction
Status: COMPLETED
Conditions: Lipid Profile|Neonates|Intrauterine Growth Restriction
Interventions: DIETARY_SUPPLEMENT: Omega-3 supplement group|OTHER: Full feeding without receiving any supplementation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FMT in Checkpoint Inhibitor-mediated Diarrhea and Colitis
Status: RECRUITING
Conditions: Diarrhea|Colitis|Malignant Melanoma|Kidney Cancer
Interventions: PROCEDURE: Faecal Microbiota Transplantation (FMT)|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Capability and Training Effects in Diabetic Patients With Neuropathy
Status: COMPLETED
Conditions: Diabetes Mellitus|Peripheral Neuropathy
Interventions: BEHAVIORAL: exercise training|BEHAVIORAL: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BetaLACTA® Test for Early De-escalation of Empirical Carbapenems in Pulmonary, Urinary and Bloodstream Infections in ICU
Status: COMPLETED
Conditions: Pneumonia|Urinary Tract Infections|Bloodstream Infection
Interventions: DEVICE: betaLACTA® rapid diagnostic test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Four Different Supplementary Foods in the Treatment of Moderate Acute Malnutrition (MAM) in Children in Sierra Leone: a Cluster-randomised, Controlled Clinical Effectiveness Trial
Status: TERMINATED
Conditions: Moderate Acute Malnutrition (MAM)
Interventions: DIETARY_SUPPLEMENT: Super Cereal Plus (SC+)|DIETARY_SUPPLEMENT: Super Cereal (SC), fortified oil, sugar|DIETARY_SUPPLEMENT: Plumpy Sup|DIETARY_SUPPLEMENT: Corn Soy Blend 14 (CSB14) and fortified oil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Metastatic or Recurrent Cancer of the Stomach or Esophagus
Status: UNKNOWN
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: FOLFIRI regimen|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Exposure to Informative Video Before Cesarean Delivery on Maternal Anxiety
Status: COMPLETED
Conditions: Maternal Distress (During Labor)|Anxiety
Interventions: BEHAVIORAL: Informative video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study on the Treatment of Bronchial Asthma With Traditional Chinese Medicine
Status: UNKNOWN
Conditions: Bronchial Asthma
Interventions: DRUG: Ke Chuan Liu Wei Mixture|DRUG: Chuan Xiong Ping Chuan Mixture|DRUG: Xie Wu Capsule|DRUG: Dan Ma Jia Tablet|DRUG: Zhi Chuan Capsule|DRUG: Bu Shen Na Qi Granule|DRUG: Ke Chuan Liu Wei Mixture placebo|DRUG: Chuan Xiong Ping Chuan Mixture placebo|DRUG: Xie Wu Capsule placebo|DRUG: Dan Ma Jia Tablet placebo|DRUG: Zhi Chuan Capsule placebo|DRUG: Bu Shen Na Qi Granule placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Coagulation Profile by Thromboelastography in Bariatric Patients
Status: COMPLETED
Conditions: Bariatric Patients Undergoing Bariatric Surgery
Interventions: OTHER: blood test by thromboelastography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Drosophila-generated CTL
Status: TERMINATED
Conditions: Metastatic Cutaneous Melanoma
Interventions: DRUG: fludarabine|DRUG: cyclophosphamide|DRUG: Drosophila-peptide pulsed Melanoma-reactive autologous CD8+ PBL|DRUG: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Brimonidine Purite, Dorzolamide, and Brinzolamide as Adjunctive Therapy to Prostaglandin Analogs
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Brimonidine purite 0.15%|DRUG: Dorzolamide 2%|DRUG: Brinzolamide 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Imatinib Mesylate in Patients With Refractory Desmoplastic Small Round Cell Tumors
Status: COMPLETED
Conditions: Refractory Desmoplastic Small Round Cell Tumors
Interventions: DRUG: Imatinib mesilate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT