pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Cellutome System for Treatment of Individual Lesions in EB Pts
Status: COMPLETED
Conditions: Epidermolysis Bullosa
Interventions: DEVICE: Cellutome Epidermal Harvesting System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: D Vitamine and Whole Body Vibration in Functional Outcomes
Status: UNKNOWN
Conditions: COPD|Aging
Interventions: DIETARY_SUPPLEMENT: Vitamine D supplementation|OTHER: chronic exercise in whole body vibration (WBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HPV Self-sampling to Improve Access to Cervical Cancer Screening for Persons With HIV and/or Underserved Individuals
Status: ENROLLING_BY_INVITATION
Conditions: Cervical Cancer
Interventions: DEVICE: Flocked swab paired with Roche Cobas 4800
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab
Status: RECRUITING
Conditions: Crohn's Disease
Interventions: DRUG: Vorinostat|DRUG: Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The JustWalk JITAI Study: A System Identification Experiment to Understand Just-in-Time States of Physical Activity
Status: COMPLETED
Conditions: Physical Inactivity|Health Behavior|Healthy Lifestyle
Interventions: BEHAVIORAL: System identification experiment for physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Distal Thigh Compression Garment Improves Knee Control and Safety Perceptions During Single Leg Triple Hop for Distance
Status: COMPLETED
Conditions: Neuromuscular Control
Interventions: DEVICE: Distal Thigh Compression Garment, Knee Sleeve
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase II Study DCVAC/OvCa Added to First Line Carboplatin and Paclitaxel Newly Diagnosed Epithelial Ovarian Carcinoma
Status: COMPLETED
Conditions: Ovarian Neoplasms|Ovarian Epithelial Cancer
Interventions: BIOLOGICAL: DCVAC/OvCa with Standard of Care|BIOLOGICAL: DCVAC/OvCa sequentially chemotherapy|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Pharmacokinetic Drug Interactions and Safety of Clarithromycin, Amoxicillin and Ilaprazole
Status: COMPLETED
Conditions: Drug Interaction Potentiation
Interventions: DRUG: Ilaprazole 10mg|DRUG: Clarithromycin 500mg|DRUG: Amoxicillin 500 Mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antipsychotic Effects of Oxytocin
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Oxytocin|DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid Start vs. Standard Start Antiretroviral Therapy (ART) in HIV
Status: TERMINATED
Conditions: HIV/AIDS
Interventions: DRUG: bictegravir/emtricitabine/tenofovir alafenamide (BIC/F/TAF)|DRUG: Standard initiation of antiretroviral therapy (ART)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study To Evaluate the Efficacy of Response Guided Therapy of Peginterferon Alfa Plus Ribavirin in the Treatment of Patients With HCV/HBV Co-Infection
Status: COMPLETED
Conditions: HBV/HCV Co-infection
Interventions: OTHER: Abbreviation of treatment duration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing the Onset and Duration of Ultrasound Guided Supraclavicular Nerve Blocks Using Ropivacaine Versus Ropivacaine-Chloroprocaine Mixture
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ropivacine and Chloroprocaine mixture|DRUG: Ropivacaine only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of the CPS+EG, Neo-Bioscore and Modified Neo-Bioscore Staging Systems After PST of BC in China
Status: COMPLETED
Conditions: Breast Cancer|Neoadjuvant Therapy|Neoplasm Staging|Estrogen Receptor|Histological Grade|HER2|Prognosis|Predictive Value of Tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Relative Oral Bioavailability of BI 44847 as Suspension Compared to Tablet and the Influence of Food Anf of BI 44847 as Solution Compared to Tablet in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 44847 solution, low dose|DRUG: BI 44847 suspension, high dose|DRUG: BI 44847 tablet, low dose|DRUG: BI 44847 tablet, high dose|OTHER: high fat breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketorolac Levels in Vitreous and Aqueous Samples From Patients Undergoing Combined Cataract and Pars Plana Vitrectomy Surgeries With and Without Intracameral Phenylephrine 1.0% / Ketorolac 0.3%
Status: RECRUITING
Conditions: Cataract
Interventions: COMBINATION_PRODUCT: OMIDRIA (*Registered Product) {10.16 mg/mL (1% w/v) of phenylephrine and 2.88 mg/mL (0.3% w/v) of ketorolac}|OTHER: Ketorolac Tromethamine {TORADOL} (0.5%) - Topical Eyedrop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CBTpro: Scaling up CBT for Psychosis Using Simulated Patients and Spoken Language Technologies
Status: ENROLLING_BY_INVITATION
Conditions: Psychosis|Schizophrenia|Schizo Affective Disorder|Bipolar Disorder|Depressive Disorder
Interventions: BEHAVIORAL: CBTpro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ib Study of CBP-1019 in Combination With FOLFOX +/- Bevacizumab, Pembrolizumab, or Enzalutamide for Metastatic TRPV6-overexpressing Solid Tumors of Epithelial Origin
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: CBP-1019|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: 5-FLUOROURACIL|DRUG: Bevacizumab|DRUG: Pembrolizumab|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Trial of Vinflunine Plus Best Supportive Care vs. Best Supportive Care in Patients With Transitional Cell Carcinoma (TCC) of the Urothelial Tract
Status: COMPLETED
Conditions: Transitional Cell Carcinoma of the Urothelial Tract|Bladder Cancer|Bladder Neoplasms
Interventions: DRUG: vinflunine and best supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Intensity Pulsed Ultrasound Versus High Intensity Continuous Ultrasound Therapy in Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis, Knee|Osteoarthritis|Rheumatic Diseases|Musculoskeletal Diseases
Interventions: DEVICE: Low intensity pulsed ultrasound|DEVICE: High intensity continuous ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Encouraging Flu Vaccination Among High-Risk Patients Identified by ML
Status: COMPLETED
Conditions: Influenza|Vaccination|Health Promotion|Health Behavior|Risk Reduction
Interventions: BEHAVIORAL: Risk reduction|BEHAVIORAL: Medical records-based recommendation|BEHAVIORAL: Algorithm-based recommendation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study Testing Feasibility of Health Screening at Farm Site
Status: COMPLETED
Conditions: Diabetes Screening|Hyperlipidemia Screening|Hypertension Screening
Interventions: OTHER: Worksite screening for DM, HTN and hyperlipidemia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bortezomib After Combination Chemotherapy, Rituximab, and an Autologous Stem Cell Transplant in Treating Patients With Mantle Cell Lymphoma
Status: UNKNOWN
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correction of Enophthalmos and Orbital Volume Using Pre-bent Mesh Versus 3d Printed Onlay in Orbital Fracture Cases
Status: UNKNOWN
Conditions: Orbital Fractures|Enophthalmos|Periorbital Fracture
Interventions: COMBINATION_PRODUCT: 3D printed PEEK onlay|COMBINATION_PRODUCT: Pre-bent orbital mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interests of Strengthening Isokinetic Upper Extremity Hemiparetic Sequelae in Patients
Status: TERMINATED
Conditions: Partial Deficiency of Muscle Strength
Interventions: OTHER: isokinetic strength training|OTHER: passive motion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Compare the Effects of NLSCP and Interactive ICT Supported HAP on Differentiate Diagnosed Thyroid Cancer Patients
Status: RECRUITING
Conditions: Differentiated Thyroid Cancer
Interventions: OTHER: NLSCP|OTHER: ICT supported HAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mental Health Among Patients, Providers, and Staff During the COVID-19 Era
Status: COMPLETED
Conditions: Covid19|Mental Health
Interventions: OTHER: Caring Contacts Plus Introductory Phone Call (CC+)|OTHER: Caring Contacts without an introductory phone call (CC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Trial Comparing Capecitabine in Combination With Sorafenib or Placebo in the Treatment of Locally Advanced or Metastatic HER2-Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)|DRUG: Placebo|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study Evaluating Topical Benzocaine for Treatment of Acute Otitis Media in Children
Status: COMPLETED
Conditions: Pain|Acute Otitis Media
Interventions: DRUG: Benzocaine Otic Solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Vestibular Rehabilitation on MS-related Fatigue: a Randomized Control Trial
Status: COMPLETED
Conditions: Multiple Sclerosis|Fatigue|Balance|Dizziness
Interventions: OTHER: Exercise: Vestibular Rehabilitation|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Leuprolide Acetate 45 mg 6-Month Formulation in Children With Central Precocious Puberty (CPP)
Status: COMPLETED
Conditions: Central Precocious Puberty (CPP)
Interventions: DRUG: Leuprolide Acetate (LA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Lycopene/Ateronon for Secondary Prevention of Coronary Heart Disease
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DRUG: Ateronon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ration Formulations on Warfighter Energy Balance and Physical Performance During a Field Training Exercise
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers
Interventions: OTHER: CCAR|OTHER: FSR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Sodium Bicarbonate on 24-hour Urine Parameters in Hypocitriuric and Uric Acid Stone Formers
Status: NOT_YET_RECRUITING
Conditions: Uric Acid Stones
Interventions: DRUG: Potassium citrate|DRUG: Sodium bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD7 CAR-T Cells for Patients With R/R CD7+ NK/T Cell Lymphoma,T-lymphoblastic Lymphoma and Acute Lymphocytic Leukemia
Status: UNKNOWN
Conditions: T-lymphoblastic Lymphoma|NK/T Cell Lymphoma|Acute Lymphocytic Leukemia
Interventions: DRUG: CD7 CAR-T cells infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phlogenzym® in Patients With Acute Thrombophlebitis - Efficacy and Tolerance
Status: COMPLETED
Conditions: Thrombophlebitis Leg
Interventions: DRUG: Phlogenzym|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Compare Efficacy and Safety of Primapur and Gonal-f in Women for Assisted Reproductive Treatment
Status: COMPLETED
Conditions: Infertility, Female
Interventions: DRUG: Follitropin alfa (Gonal-f)|DRUG: Follitropin alfa (Primapur)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Children With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Childhood Acute Lymphoblastic Leukemia in Remission|Recurrent Childhood Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: filgrastim|DRUG: asparaginase|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: dexamethasone|DRUG: etoposide|DRUG: ifosfamide|DRUG: imatinib mesylate|DRUG: leucovorin calcium|DRUG: mercaptopurine tablet|DRUG: methotrexate|DRUG: pegaspargase|DRUG: vincristine sulfate|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: umbilical cord blood transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Switching to DTG/3TC in Virologically-suppressed Adults Currently on B/F/TAF
Status: COMPLETED
Conditions: HIV I Infection
Interventions: DRUG: Dolutegravir / Lamivudine Pill|DRUG: Bictegravir / Emtricitabine / Tenofovir Alafenamide Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BAY43-9006 (Sorafenib) Versus Interferon Alpha-2a in Patients With Unresectable and/or Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)|DRUG: Interferon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study of the Long-Term Safety, Tolerability, and Efficacy of Tividenofusp Alfa (DNL310) in Participants With Mucopolysaccharidosis Type II (MPS II) From Study DNLI-E-0002 or Study DNLI-E-0007
Status: ENROLLING_BY_INVITATION
Conditions: Mucopolysaccharidosis II
Interventions: DRUG: tividenofusp alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma
Status: ACTIVE_NOT_RECRUITING
Conditions: Biphasic Mesothelioma|Epithelioid Mesothelioma|Stage I Pleural Malignant Mesothelioma AJCC v7|Stage IA Pleural Malignant Mesothelioma AJCC v7|Stage IB Pleural Malignant Mesothelioma AJCC v7|Stage II Pleural Malignant Mesothelioma AJCC v7|Stage III Pleural Malignant Mesothelioma AJCC v7
Interventions: DRUG: Atezolizumab|DRUG: Cisplatin|PROCEDURE: Extrapleural Pneumonectomy|DRUG: Pemetrexed Disodium|PROCEDURE: Pleurectomy|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study to Evaluate the Effect of RT234 in Subjects With Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: COMBINATION_PRODUCT: Drug: RT234 - vardenafil inhalation powder; Device: RS01 dry powder inhaler (RS01 DPI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Organ Preservation Program Using Short-Course Radiation & FOLFOXIRI in Rectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Rectal Cancer
Interventions: DRUG: FOLFOXIRI|DRUG: FOLFOX regimen|DRUG: XELOX|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of MCI-196 Versus Simvastatin for Dyslipidaemia in Chronic Kidney Disease (CKD) Subjects on Dialysis
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: MCI-196|DRUG: Placebo of Simvastatin|DRUG: Simvastatin|DRUG: Placebo of MCI-196
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mental Practice Combined With Physical Practice to Improve the Gait Performance of People With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Experimental training|BEHAVIORAL: Control training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Low-residue Diet vs Clear Liquid Diet as a Bowel Colonoscopy Preparation With Polyethylene Glycol (PEG)
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DIETARY_SUPPLEMENT: Clear Liquid Diet|DIETARY_SUPPLEMENT: Low-residue Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Lay Health Worker Model to Reduce Liver Cancer Disparities in Asian Americans
Status: COMPLETED
Conditions: Liver Neoplasms|Hepatitis B
Interventions: BEHAVIORAL: Lay Health Worker Intervention|BEHAVIORAL: Placebo (a list of resources)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized Controlled Trial of the Mindful Compassion Care Program in Reducing Psychological Distress Amongst Nurses During the COVID-19 Pandemic
Status: COMPLETED
Conditions: Burnout|COVID-19
Interventions: BEHAVIORAL: Mindful Compassion Care Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect and Safety of Lisinopril in Non-hypertensive Men With Infertility From Low Sperm Count
Status: COMPLETED
Conditions: Oligospermia
Interventions: DRUG: Lisinopril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Marginal Bone Level Around Titanium Implants Produced by Additive Manufacture
Status: RECRUITING
Conditions: Dental Implants
Interventions: DEVICE: Dental implant produced by additive manufacture|DEVICE: Dental implant produced by additive manufacture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Rituximab in Treating Patients With Untreated Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Contiguous Stage II Mantle Cell Lymphoma|Noncontiguous Stage II Mantle Cell Lymphoma|Stage I Mantle Cell Lymphoma|Stage III Mantle Cell Lymphoma|Stage IV Mantle Cell Lymphoma
Interventions: DRUG: bortezomib|BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: vincristine|DRUG: dexamethasone|BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim|PROCEDURE: Autologous stem cell transplantation (ASCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NMES in HF Patients to Improve Functional Recovery Following Hospitalization
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DEVICE: Neuromuscular electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analgesia Nociception Index-guided Anesthesia and Standard Anesthesia
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: BEHAVIORAL: Analgesia nociception index-guided anesthesia|BEHAVIORAL: Standard anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SARS-CoV-2 Human Challenge Characterisation Study
Status: COMPLETED
Conditions: Covid19|SARS-CoV Infection|Corona Virus Infection|Coronavirus|COVID-19
Interventions: BIOLOGICAL: SARS-CoV-2 Virus|DRUG: Remdesivir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fetal Surgery for Moderate Left Sided Congenital Diaphragmatic Hernia.
Status: COMPLETED
Conditions: Congenital Diaphragmatic Hernia|Fetal Surgery|Pulmonary Hypoplasia
Interventions: PROCEDURE: Fetoscopic Endoluminal Tracheal Occlusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics, and Efficacy of 100, 150, and 200 mg Risedronate Administered to Women With Low BMD
Status: COMPLETED
Conditions: Postmenopausal
Interventions: DRUG: risedronate|DRUG: risedronate|DRUG: risedronate|DRUG: experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Pregnancy on Oral Health
Status: COMPLETED
Conditions: Pregnancy Related|Dental Caries|Periodontal Diseases|Saliva Altered
Interventions: DIAGNOSTIC_TEST: Evaluation of DMFT index, CPI scores, salivary pH and flow rate in pregnant and non-pregnant woman
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Botswana Smoking and Abstinence Reinforcement Trial
Status: ENROLLING_BY_INVITATION
Conditions: Smoking Cessation|Hiv
Interventions: BEHAVIORAL: Screening, Brief Intervention and Referral to Treatment (SBIRT) intervention consisting of the 5As, (Ask, Advise, Assess, Assist, Arrange)|DRUG: Varenicline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Myofascial Pain:Acupuncture Versus Trigger Point Injection Combined With Dipyrone and Cyclobenzaprine
Status: COMPLETED
Conditions: Myofascial Pain Syndromes
Interventions: DRUG: bupivacaine and acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Effects of Three Recruitment Maneuvers on the Lung Heterogeneity of Acute Respiratory Distress Syndrome
Status: UNKNOWN
Conditions: Acute Respiratory Distress Syndrome
Interventions: BEHAVIORAL: SI recruitment|BEHAVIORAL: IP recruitment|BEHAVIORAL: PCV recruitment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Seroma Following Inguinal Lymph Node Dissection With Prophylactic Incisional Negative Pressure Wound Therapy
Status: TERMINATED
Conditions: Seroma|Surgical Site Infection|Lymphedema|Quality of Life
Interventions: DEVICE: Negative pressure wound therapy|OTHER: Micropore tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dose-Finding Study of Vadadustat in Japanese Subjects With Anemia Secondary to Non-Dialysis Dependent Chronic Kidney Disease (NDD-CKD)
Status: COMPLETED
Conditions: Anemia|Non-dialysis Dependent Chronic Kidney Disease
Interventions: DRUG: Vadadustat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Randomized Controlled Trial of a Collaborative Agenda-setting Intervention (CASI) for Patients With Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Ovarian Cancer|Ovarian Neoplasms|Ovarian Carcinoma
Interventions: BEHAVIORAL: Collaborative Agenda-Setting Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: S-1 Plus Gefitinib Versus Gefitinib Monotherapy in Patients With EGFR-sensitive Mutation Advanced Non-squamous NSCLC
Status: UNKNOWN
Conditions: Advanced NSCLC With EGFR Mutation
Interventions: DRUG: S-1 plus Gefitinib|DRUG: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics and Safety of Levofloxacin in Patients With Varying Degrees of Renal Function.
Status: COMPLETED
Conditions: Renal Diseases
Interventions: DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peer-delivered and Technology-Assisted Integrated Illness Management and Recovery
Status: COMPLETED
Conditions: Schizophrenia|Bipolar Disorder|Major Depressive Disorder, Recurrent|Obesity|Cardiovascular Diseases|Diabetes|Smoking|Blood Pressure Disorders|Cholesterol, Elevated
Interventions: BEHAVIORAL: Peer-delivered and Technology Support Integrated Illness Management and Recovery|BEHAVIORAL: Peer support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplantation for Sickle Cell Anemia
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: Alemtuzumab|DRUG: Fludarabine|DRUG: Melphalan|PROCEDURE: Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-protozoal Effect of Steroid Hormone 20-hydroxyecdysone
Status: ACTIVE_NOT_RECRUITING
Conditions: Giardia Lamblia Infection
Interventions: DRUG: 20-hydroxyecdysone Oral|DRUG: Metronidazole Oral|DRUG: Placebo Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: YIV-906 (Formerly PHY906/KD018) With Sorafenib in HBV(+) Hepatocellular Carcinoma (HCC)
Status: UNKNOWN
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: YIV-906+Sorafenib|DRUG: Placebo+Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain After Ultrasonically and Laser-activated Irrigation During Root Canal Treatment
Status: COMPLETED
Conditions: Post-operative Pain
Interventions: DEVICE: Laser-activated irrigation with a pulsed Er:YAG laser|DEVICE: Ultrasonically activated irrigation|PROCEDURE: Orthograde root canal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Semaglutide and Dapagliflozin in Diabetic Patients With Different Pathophysiology
Status: ACTIVE_NOT_RECRUITING
Conditions: Type2 Diabetes
Interventions: DRUG: Semaglutide|DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HOme-Based Self-management and COgnitive Training CHanges Lives (HOBSCOTCH) - Multiple Sclerosis (MS)
Status: RECRUITING
Conditions: Multiple Sclerosis|Cognitive Dysfunction|Memory Disorders
Interventions: BEHAVIORAL: HOme-Based Self-management and COgnitive Training CHanges lives (HOBSCOTCH)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effectiveness of Orally Dosed Emergency Contraception in Obese Women - UPA
Status: COMPLETED
Conditions: Obesity|Contraception
Interventions: DRUG: UPA-ECx1|DRUG: UPA-ECx2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Model-based Iterative Reconstruction (MB-IR VEOTM) in Ultra Low-dose Abdominal CT Versus Adaptative Statistical Iterative Reconstruction (ASIR): A Prospective Study for Acute Renal Colic
Status: COMPLETED
Conditions: Model-based Iterative Reconstruction (MB-IR VEOTM)
Interventions: DEVICE: Model-based iterative reconstruction (MB-IR VEOTM) on CT Discovery 750HD (GE Healthcare, Milwaukee, WI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Bonfils Fiberscope for Predicted Difficult Intubation in Awake Patients With Ear, Nose, and Throat (ENT) Cancer (INVIBO)
Status: COMPLETED
Conditions: Carcinoma
Interventions: DEVICE: Bonfils fiberscope intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose:
Clinical trial: Prospects for the Prevention of Pregnancy-induced Hypertension and Preeclampsia Trial
Status: UNKNOWN
Conditions: Pregnancy Induced Hypertension
Interventions: DRUG: Combined aspirin and multinutrient supplement|OTHER: Daily text reminder text messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hyperbaric Oxygen Therapy Effect on Post Concussion Syndrome in Children
Status: TERMINATED
Conditions: Hyperbaric Oxygen Therapy|Traumatic Brain Injury|Post-Concussion Syndrome
Interventions: DEVICE: Hyperbaric oxygen therapy|DEVICE: Normobaric air SHAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Oral Mucosa Evaluation - Acceptability With Odontological Follow up - Cepacol Canela Power
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cetylpyridinium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ibrutinib and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma
Status: COMPLETED
Conditions: CD20 Positive|Recurrent Diffuse Large B-Cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Carboplatin|DRUG: Etoposide|DRUG: Ibrutinib|DRUG: Ifosfamide|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Letrozole and Metronomic Capecitabine in ER-positive HER2 Negative Advanced Breast Cancer (B-001 Study)
Status: UNKNOWN
Conditions: Breast Cancer|Estrogen Receptor-positive Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: Capecitabine|DRUG: Letrozole 2.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abdominal Wall Local Anesthesia to Maximize Postoperative Pain Control After Cesarean Delivery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Saline placebo|DRUG: Ropivicaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Supplementation for Tetraplegics With Poor Cholesterol Levels
Status: COMPLETED
Conditions: Spinal Cord Injury|Tetraplegia|Quadraplegia|Low HDL-c|High LDL-c
Interventions: DIETARY_SUPPLEMENT: Omega-3 supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiosurgery for Localised Prostate Cancer (HYPOSTAT-II)
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Hypofractionated Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of App and Electronic Device in the Treatment of Premature Ejaculation
Status: COMPLETED
Conditions: Premature Ejaculation|Masturbation|Medical Device
Interventions: DEVICE: Sphincter Control Training (SCT)|BEHAVIORAL: Sphincter Control Training (SCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PICSO in Patients With STEMI Treated by Primary Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: ST Elevation (STEMI) Myocardial Infarction
Interventions: DEVICE: PICSO (Pressure-controlled Intermittent Coronary Occlusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-intensity Small-sided Soccer Games for Cardiometabolic Health in Adolescents With Metabolic Dysfunction
Status: COMPLETED
Conditions: Obesity, Adolescent|Metabolic Syndrome
Interventions: BEHAVIORAL: Small-sided soccer games groups (SSSG)|BEHAVIORAL: Traditional soccer training groups (TSG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Study of the Submentonian Musculature and Its Relationship in Dysphagia
Status: NOT_YET_RECRUITING
Conditions: Dysphagia, Oropharyngeal|Deglutition Disorders|Mechanical Ventilation Complication
Interventions: DIAGNOSTIC_TEST: Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Selinexor, in Combination With Carfilzomib, Daratumumab or Pomalidomide in Patients With Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Selinexor 60 MG|DRUG: Selinexor 80 MG|DRUG: Selinexor 100 MG|DRUG: Carfilzomib|DRUG: Pomalidomide|DRUG: Daratumumab|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Tumor Debulking Surgery Versus Chemotherapy Alone in Recurrent Platinum-Sensitive Ovarian Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: PROCEDURE: Tumor Debulking Surgery (surgery in recurrent ovarian disease)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ImpleMEntation of a Digital-first Care deLiverY Model for Heart Failure in Uganda
Status: NOT_YET_RECRUITING
Conditions: Heart Failure
Interventions: OTHER: Enhanced HF Clinical Care (Core-HF)|OTHER: Digital health intervention (Medly Uganda) plus enhanced HF clinical care (Core-HF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Effect of Elastic Compression (French Class III) on Water Balance Change in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DEVICE: Compression stocking|OTHER: No use of compression stocking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Transcranial Magnetic Stimulation in Incomplete Spinal Cord Injury
Status: UNKNOWN
Conditions: Spinal Cord Injury
Interventions: DEVICE: Active high-frequency Transcranial Magnetic Stimulation|DEVICE: Sham high-frequency Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antineoplaston Therapy in Treating Adult Patients With Anaplastic Astrocytoma
Status: COMPLETED
Conditions: Adult Brain Tumor
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Raloxifene and Lasofoxifene - A Randomized, Blinded Study of These Drugs and Placebo on Bone Loss
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: lasofoxifene|DRUG: raloxifene|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Treatment for Internalized Stigma in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Narrative Enhancement and Cognitive Therapy|BEHAVIORAL: Supportive Group Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Boceprevir/PegIFN α-2b/Riba in HCV+ Gt1 Menopausal Women, Nonresponders to PegIFN/Riba or Treatment-naives (MEN_BOC)
Status: UNKNOWN
Conditions: Chronic Hepatitis C|Menopause
Interventions: DRUG: Pegylated Interferon, Ribavirin, Boceprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Ranging Study to Assess the Safety, PK and Initial Antiviral Efficacy of NVR 3-778 in Chronic HBV Patients
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: NVR 3-778|DRUG: Placebo for NVR 3-778|DRUG: Pegasys
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Prostate Radiotherapy With Dose Escalation Focused on the "Dominant Intra-prostatic Lesion" (DIPL) Delineated by Multi-parametric MRI and 68Ga-PSMA PET (Prostate-SIB-PSMA)
Status: UNKNOWN
Conditions: Prostate Adenocarcinoma
Interventions: RADIATION: Integrated boost
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Step Down Approach in Children With Cow Milk Allergy
Status: COMPLETED
Conditions: Allergy Milk
Interventions: DIETARY_SUPPLEMENT: extensively hydrolyzed casein formula + LGG|DIETARY_SUPPLEMENT: Hypoallergenic formula based on amino-acid based formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of BI 1356 With and Without Co-administration of Pioglitazone and the Bioavailability of Pioglitazone With and Without Coadministration of BI 1356 in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1356|DRUG: BI 1356 + Pioglitazone|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cordotomy in Reducing Pain in Patients With Advanced Cancer
Status: RECRUITING
Conditions: Advanced Malignant Neoplasm
Interventions: PROCEDURE: Cordotomy|DRUG: Morphine|OTHER: Questionnaire Administration|PROCEDURE: Sham Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Arterial Properties by Ultra-high Frequency Ultrasound in Fibromuscular Dysplasia and Vascular Ehlers-Danlos Syndrome
Status: UNKNOWN
Conditions: Ehlers-Danlos Syndrome|Fibromuscular Dysplasia
Interventions: DEVICE: Ultra High Frequency ultrasound system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Optimal Interstimulus Interval For Consecutive H-Reflex Responses In Patients With Spasticity
Status: COMPLETED
Conditions: Muscle Hypertonia|Reflex, Abnormal
Interventions: DIAGNOSTIC_TEST: H-reflex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Controlled Study to Evaluate the Safety and Immunogenicity of StreptAnova™ in Healthy Adults
Status: UNKNOWN
Conditions: Healthy
Interventions: BIOLOGICAL: StreptAnova™ (Group A streptococcal (GAS) vaccine)|BIOLOGICAL: Hepatitis B vaccine|BIOLOGICAL: Hepatitis A vaccine|BIOLOGICAL: Human Papillomavirus vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Fixed Lingual Mandibular Growth Modificator
Status: COMPLETED
Conditions: Class II Division 1 Malocclusion|Retrognathic Mandible
Interventions: DEVICE: Fixed Lingual Mandibular Growth Modificator (FLMGM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Periodontal Profile of Hypogonadic Men
Status: WITHDRAWN
Conditions: Periodontitis|Hypogonadism, Male
Interventions: DRUG: Testosterone gel|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Building an Outcomes Assessment Infrastructure to Assess Anxiety Treatment
Status: RECRUITING
Conditions: Social Anxiety Disorder|Specific Phobia|Separation Anxiety Disorder|Panic Disorder|Agoraphobia|Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: McLean Anxiety Mastery Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combining Wearable Robotic Orthosis With Visual and Haptic Feedback to Enhance the Recovery of Upper Extremity Motor Function and ADL in Persons With Acute SCI
Status: RECRUITING
Conditions: SCI - Spinal Cord Injury
Interventions: COMBINATION_PRODUCT: MyoMo orthosis and VR games|DEVICE: MyoPro robot only|OTHER: Games only|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Fascial Duplication Plus Sacral Colpopexy in Posterior Vaginal Prolapse
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|Posterior Vaginal Wall Prolapse
Interventions: PROCEDURE: Laparoscopic Fascial Posterior Vagina Duplication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iyengar Yoga for Chemotherapy-induced Fatigue in Breast Cancer Patients
Status: WITHDRAWN
Conditions: Breast Neoplasms|Fatigue
Interventions: BEHAVIORAL: Iyengar Yoga|BEHAVIORAL: Walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupressure Therapy on Post-stroke Fatigue, Depression, and Sleep Disturbances in Ischemic Stroke Patients
Status: RECRUITING
Conditions: Inflammatory Cytokine|Circadian Rhythm|Acupressure|Post-stroke Fatigue|Sleep|Ischemic Stroke
Interventions: BEHAVIORAL: Circadian based acupressure application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Tolerance and Alloreactivity in Liver Transplant Recipients on Different Monotherapy Immunosuppressive Agents
Status: COMPLETED
Conditions: Liver Transplant Rejection|Immunosuppression
Interventions: PROCEDURE: Blood Draw - Rapamycin|PROCEDURE: Blood Draw from Control Subjects|PROCEDURE: Blood Draw - CyA|PROCEDURE: Blood Draw - Tacrolimus|PROCEDURE: Blood Draw - MMF|PROCEDURE: Blood Draw - Rapamycin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TMS for Exposure Therapy Resistant OCD
Status: RECRUITING
Conditions: 1 Hz Real rTMS to the Pre-SMA|1 Hz Sham rTMS to the Pre-SMA
Interventions: COMBINATION_PRODUCT: repetitive transcranial magnetic stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT