pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Patient-Centred Innovations for Persons With Multimorbidity - Quebec
Status: COMPLETED
Conditions: Hypertension|Depression|Anxiety|Musculoskeletal Pain|Arthritis|Rheumatoid Arthritis|Osteoporosis|Chronic Obstructive Pulmonary Disease (COPD)|Asthma|Chronic Bronchitis|Cardiovascular Disease|Heart Failure|Stroke|Transient Ischemic Attacks|Ulcer|Gastroesophageal Reflux|Irritable Bowel|Crohn's Disease|Ulcerative Colitis|Diverticulosis|Chronic Hepatitis|Diabetes|Thyroid Disorder|Cancer|Kidney Disease|Urinary Tract Problem|Dementia|Alzheimer's Disease|Hyperlipidemia|HIV
Interventions: BEHAVIORAL: DIMAC02
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study (Study 2) to Evaluate the Safety and Efficacy of FMX103 1.5% Topical Minocycline Foam in the Treatment of Facial Papulopustular Rosacea
Status: COMPLETED
Conditions: Facial Papulopustular Rosacea
Interventions: DRUG: FMX103 minocycline foam 1.5%|DRUG: Vehicle foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Subcutaneous Infusions of 3 Doses of DG3173 on Growth Hormone Levels in Untreated Acromegalics
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: saline|DRUG: DG3173|DRUG: octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of DS-8201a in Subjects With Advanced Solid Malignant Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: DS-8201a (DP1)|DRUG: DS-8201a (DP2)|DRUG: DS-8201a (DP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Penn Microbiome Therapy (PMT) for Severe-Clostridium Difficile Infection (CDI)
Status: TERMINATED
Conditions: Severe Clostridium Difficile Infection|Severe-Complicated/Fulminant Clostridium Difficile Infection
Interventions: DRUG: Penn Microbiome Therapy - 001|DRUG: Penn Microbiome Therapy - 002|DRUG: Penn Microbiome Therapy - 003|DRUG: Antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OMEGA Study: A Study of the Safety and Feasibility of Up-titration With INT301 in Adults With Sensitivity to Peanut
Status: COMPLETED
Conditions: Peanut Allergy
Interventions: DRUG: INT301|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Airway Inflammation Effects of FlutiForm® pMDI Low and High Dose in Adults With Mild to Moderate Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone propionate / Formoterol fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Screening Nasopharyngeal Carcinoma With EBV Associated Biomarkers in Zhongshan City
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: BIOLOGICAL: Blood and saliva|DIAGNOSTIC_TEST: P85-Ab, EBNA1-IgA, VCA-IgA and EBV DNA|DIAGNOSTIC_TEST: Fiberoptic endoscopy and biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Research Study of Greater Occipital Nerve Block as a Treatment for Acute Migraine Attacks
Status: WITHDRAWN
Conditions: Migraine
Interventions: DRUG: Saline|COMBINATION_PRODUCT: lidocaine/bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Safety of Pharmaceutical Grade Synthetic Cannabidiol Oral Solution in Pediatric Participants With Treatment-Resistant Childhood Absence Seizures
Status: TERMINATED
Conditions: Childhood Absence Epilepsy
Interventions: DRUG: Cannabidiol Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bilateral Transversus Abdominis Plane Block and Postoperative Pain Intensity After Elective Cesarean Delivery
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: PROCEDURE: TAP blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RELIEF OF PSYCHOEMOTIONAL STRESS USING XENON SEDATION
Status: RECRUITING
Conditions: Psychological Stress|Anesthesia|Anxiety|Xenon
Interventions: DRUG: Xenon|OTHER: premedication hydroxyzine 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Intravenous Dexamethasone on the Duration of Analgesia of Ultrasound Guided Axillary Brachial Plexus Block in Pediatric Patients Undergoing Below Elbow Orthopaedic Surgeries
Status: UNKNOWN
Conditions: Axillary Brachial Plexus Block
Interventions: PROCEDURE: Ultrasound guided axillary block with intravenous dexamethasone|PROCEDURE: Ultrasound guided axillary block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: AGEN2034 & AGEN1884 in Patients With Recurrent, Inoperable Angiosarcoma
Status: WITHDRAWN
Conditions: Angiosarcoma
Interventions: DRUG: AGEN2034|DRUG: AGEN1884
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health Equity: Advance Care Planning for Spanish Speaking Teens With Cancer-1st Resubmission
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: FACE-TC SP|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Evaluating the Utility of Ambrisentan in Lowering Portal Pressure in Patients With Liver Cirrhosis
Status: TERMINATED
Conditions: Cirrhosis|Portal Hypertension|Ascites
Interventions: DRUG: Ambrisentan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Subcutaneous Injection of Normal Saline and Bacteriostatic Saline
Status: UNKNOWN
Conditions: Injection Site Irritation|Injection Site Bruising|Injection Site Discomfort|Benzoic Acid Adverse Reaction|Anesthesia, Local
Interventions: DRUG: Sodium Chloride 0.9% Inj|DRUG: Bacteriostatic Sodium Chloride 0.9 % INJECTION VIAL (ML)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Exercise Therapy and Soft Brace on Knee Osteoarthritis
Status: RECRUITING
Conditions: Rehabilitation|Treatment Outcome|Pain|Knee Brace|Outcome Assessment (Health Care)|Recovery of Function|Patient Reported Outcome Measures|Adults|Osteoarthritis, Knee
Interventions: OTHER: Exercise therapy and education.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Therapeutically Alternatives In Ventilator-Induced Diaphragm Dysfunction Critically Ill Patients
Status: NOT_YET_RECRUITING
Conditions: Ventilator-Induced Diaphragmatic Dysfunction
Interventions: DEVICE: Practice flow trigger sensitivity adjustment on mechanical ventilation for 1 week twice daily in addition to their plan of treatment.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lifetech CeraFlex™ ASD Closure System Post-Market Clinical Follow-Up
Status: NOT_YET_RECRUITING
Conditions: Atrial Septal Defect
Interventions: DEVICE: CeraFlex™ Atrial Septal Defect (ASD) Closure System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate ALKS 5461 in Subjects With Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: ALKS 5461|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MRI-Guided Stereotactic Body Radiation Therapy in Treating Patients With Liver Metastases or Liver Cancer
Status: COMPLETED
Conditions: Adult Hepatocellular Carcinoma|Metastatic Malignant Neoplasm in the Liver
Interventions: RADIATION: Image-Guided Adaptive Radiation Therapy|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Conventional Triple Therapy Versus Sequential Therapy for H. Pylori in Peptic Ulcer Disease: Prospective Randomized Trial
Status: COMPLETED
Conditions: Helicobacter Infected Patients
Interventions: DRUG: sequential versus triple
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating The Safety And Efficacy Of Desvenlafaxine Succinate For Vasomotor Symptoms In Menopausal Women
Status: COMPLETED
Conditions: Vasomotor Symptoms
Interventions: DRUG: desvenlafaxine succinate (DVS) SR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Timing of Complete Revascularization for Multivessel Coronary Artery Disease in STEMI
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: PROCEDURE: PCI|PROCEDURE: dobutamine stress echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label, Pivotal Clinical Trial to Confirm Efficacy and Safety of Autologous Grafts Containing Stem Cells Genetically Modified for Epidermis Restoration in Patients With Junctional Epidermolysis Bullosa
Status: UNKNOWN
Conditions: Junctional Epidermolysis Bullosa Non-Herlitz Type
Interventions: DRUG: Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remission Rate of Newly Diagnosed Type 2 Diabetes Outpatients Treated With Short-term Intensive Insulin Therapy
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: DRUG: Novolin 30R;Pioglitazone;Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Vaginal Delivery of Combined Hormonal Contraception Affect the Risk of Metabolic Syndrome in Overweight/Obese Women With PCOS
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Etonogestrel/ethinyl estradiol vaginal ring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Forced Air Warming During Caseraen Section on Maternal Hypothermia: Randomized Controlled Trial
Status: UNKNOWN
Conditions: Cesarean Section Complications|Hypothermia
Interventions: OTHER: Forced Air Warming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Taste Stimulation for Post-stroke Dysphagia
Status: RECRUITING
Conditions: Stroke|Dysphagia
Interventions: BEHAVIORAL: Favourate taste stimulation|BEHAVIORAL: Sour taste stimulation|BEHAVIORAL: Thermal stimulation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Nimotuzumab in Combination With Neoadjuvant Chemotherapy for Resectable Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma Resectable
Interventions: DRUG: Nimotuzumab combined with paclitaxel and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supporting Oral Self-care of Patients With Periodontitis Through Motivational Interview
Status: UNKNOWN
Conditions: Periodontal Diseases|Patient Education|Self-Care
Interventions: BEHAVIORAL: Motivational interview vs. prevailing education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 2 Study of ONC201 in Neuroendocrine Tumors
Status: COMPLETED
Conditions: Recurrent Neuroendocrine Tumor|Metastatic Neuroendocrine Tumor
Interventions: DRUG: ONC201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Two Daily Disposable Contact Lenses.
Status: COMPLETED
Conditions: Refractive Error|Myopia
Interventions: DEVICE: etafilcon A|DEVICE: narafilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Virtual Care of Arthritis: Integrating a Smartphone App Into the EHR for Improved Timeliness of Visits
Status: RECRUITING
Conditions: Arthritis|Psoriatic Arthritis
Interventions: OTHER: Mobile Application
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open-Label Study of Perhexiline in Patients With Hypertrophic Cardiomyopathy and Moderate to Severe Heart Failure
Status: TERMINATED
Conditions: Cardiomyopathy, Hypertrophic|Cardiomyopathy, Hypertrophic, Familial
Interventions: DRUG: Perhexiline|DEVICE: Use of bioanalytical assay to monitor plasma levels of perhexiline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Acetyl- L- Carnitine& Folic Acid Versus Coenzyme Q10& Folic Acid on Semen& Hormonal Parameters& Semen Oxidative Status in Patients of Primary Infertility. A Double Blind Randomized Clinical Trial
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Acetyl-l-carnitine, folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Shenyankangfu Tablets for Primary Glomerulonephritis
Status: UNKNOWN
Conditions: Glomerulonephritis|Proteinuria
Interventions: DRUG: Shenyankangfu tablets|DRUG: Losartan potassium 50mg|DRUG: Shenyankangfu tablets and Losartan potassium 50mg|DRUG: Shenyankangfu tablets and Losartan potassium 100mg|DRUG: Losartan potassium 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the Blazer® Open-Irrigated Catheter for Treatment of Type 1 Atrial Flutter
Status: COMPLETED
Conditions: Atrial Flutter
Interventions: DEVICE: Blazer® Open-Irrigated Ablation Catheter|DEVICE: Control Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: N-Acetylcysteine and Milk Thistle for Treatment of Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathies|Proteinuria|Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: N-acetylcysteine|DIETARY_SUPPLEMENT: silibin|DIETARY_SUPPLEMENT: high-dose silibin|DIETARY_SUPPLEMENT: N-acetylcysteine placebo|DIETARY_SUPPLEMENT: silibin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cyclosporine A or Intravenous Cyclophosphamide for Lupus Nephritis: The Cyclofa-Lune Study
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus|Lupus Nephritis
Interventions: DRUG: Cyclosporine A|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of Ivermectin for Alcohol Use Disorders
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: Ivermectin|DRUG: Placebo|DRUG: Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Treatment of Graves´ Ophthalmopathy With NSAID (aGO Study)
Status: COMPLETED
Conditions: Graves´ Disease
Interventions: DRUG: Diclofenac|DRUG: Methimazole|DRUG: L-thyroxin|DRUG: Propranolol|DRUG: Metoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intravenous Immunoglobulin Therapy for Small Fiber Neuropathy
Status: COMPLETED
Conditions: Small Fiber Neuropathy
Interventions: DRUG: Intravenous Immunoglobulin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 1-month vs 12-month DAPT for ACS Patients Who Underwent PCI Stratified by IVUS: IVUS-ACS and ULTIMATE-DAPT Trials
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DRUG: AntiPlatelet therapy|PROCEDURE: Percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Focused Shock Waves or Ultrasound-Guided Needling and Lavage in Patients With Calcifying Tendinopathy of the Shoulder
Status: RECRUITING
Conditions: Calcific Tendinopathy of Shoulders|Extracorporeal Shockwave Therapy|Ultrasound Guided Barbotage Therapy
Interventions: PROCEDURE: shockwave therapy, barbotage and infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Heat Stress on Global LV Function in Anesthetized Humans
Status: COMPLETED
Conditions: Hyperthermia|Cardiac Functional Disturbances During Surgery
Interventions: DIAGNOSTIC_TEST: Transesophageal Echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tau PET Imaging in the Northern Manhattan Study of Metabolism and Mind.
Status: ENROLLING_BY_INVITATION
Conditions: Diabetes Mellitus, Type 2|Pre-diabetes
Interventions: DRUG: 18F-MK6240 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Chronic Malnutrition and Oral Health Status in Children Aged One to Five Years
Status: COMPLETED
Conditions: Malnutrition, Child
Interventions: DIAGNOSTIC_TEST: Caries detection - dmtf index|DIAGNOSTIC_TEST: Saliva flow rate|DIAGNOSTIC_TEST: Saliva Buffering Capacity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)
Status: RECRUITING
Conditions: Focal Onset Seizures
Interventions: DRUG: XEN1101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Exercises in Patient With Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy
Interventions: OTHER: exercises for diabetic peripheral neuropathy|OTHER: Health education for diabetic foot care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Refinements of Functional Communication Training
Status: RECRUITING
Conditions: Aggression|Self-injurious Behavior
Interventions: BEHAVIORAL: Trad FCT|BEHAVIORAL: Mult FCT|BEHAVIORAL: Mult FCT + Stimulus Fading
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using AtorVASTatin to Prevent VAscular Inflammatory OccLUSion in the Critically Ill
Status: COMPLETED
Conditions: Myocardial Infarction|Stroke|Renal Failure
Interventions: DRUG: atorvastatin 80 mg per os daily|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Physical Activity Calorie Equivalent Labelling on Hot Drink Vending Transactions
Status: RECRUITING
Conditions: Averaged Kilocalories Per Beverage Transaction|Proportion of Total High Calorie Beverages|Total Number of Beverage Transactions
Interventions: BEHAVIORAL: Physical activity calorie equivalent labelling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized, Controlled Trial of Posterior C1-2 Fusion Versus Bracing Alone for Treatment of Type II Odontoid Process Fractures in the Elderly
Status: UNKNOWN
Conditions: Odontoid Fracture
Interventions: PROCEDURE: Bracing|PROCEDURE: posterior C1-C2 instrumented fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Preliminary Bioequivalence of Triferic (Ferric Pyrophosphate Citrate) Administered Via Hemodialysate and Intravenously to Adult CKD-5HD Patients
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DRUG: Triferic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes
Status: TERMINATED
Conditions: Solid Tumor
Interventions: DRUG: Rucaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RENABLATE Feasibility Study CS156 (EC12-02) Study of Catheter Based Renal Denervation to Treat Resistant Hypertension
Status: COMPLETED
Conditions: Hypertension, Renal
Interventions: DEVICE: Celsius® ThermoCool® RD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Re-treatment From a Phase I Study of MSC-AFP in Patients With Perianal Fistulas
Status: COMPLETED
Conditions: Perianal Fistula|Cryptoglandular Perianal Fistula|Crohn's Perianal Fistula
Interventions: DRUG: MSC-AFP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Iloperidone Depot in Schizophrenic Patients
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Iloperidone crystalline formulation|DRUG: Iloperidone microparticle formulation|DRUG: Oral iloperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Open-Label, Sequential Cross-over, Bioavailability/Bioequivalence Study to Compare the Pharmacokinetics of Oral Cladribine With the Reference Listed Drug, Intravenous Cladribine
Status: RECRUITING
Conditions: Leukemia|Myelodysplastic Syndromes|Acute Myeloid Leukemia
Interventions: DRUG: Cladribine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Training Program and Mobile Health Message on Promoting Family Holistic Health
Status: COMPLETED
Conditions: Physical Activity|Health Behavior|Quality of Life
Interventions: BEHAVIORAL: Holistic health training and physical exercise messages|BEHAVIORAL: Holistic Health Training with healthy diet messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: How Lidocaine Affects Outcomes In Orthopedic Surgery Patients
Status: WITHDRAWN
Conditions: General Anesthesia|Surgeries Requiring A Minimum One Day Hospitalization|Elderly
Interventions: DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose:
Clinical trial: Effects of Proteins in Patients With Cirrhosis and Prior Hepatic Encephalopathy
Status: COMPLETED
Conditions: Hepatic Encephalopathy
Interventions: DIETARY_SUPPLEMENT: Branched-chain amino acids|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Does Provision of Point of Care CD4 Technology and Early Knowledge of CD4 Levels Affect Early Initiation and Retention on Anti-retroviral Treatment (ART) in HIV Positive Pregnant Women in the Context of Option B+ for PMTCT?
Status: UNKNOWN
Conditions: HIV/AIDS
Interventions: DEVICE: POC CD4|OTHER: Programmatic Mentoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lactobacillus Gasseri DSM 27123 on Functional Constipation in Healthy Women
Status: COMPLETED
Conditions: Functional Constipation
Interventions: DIETARY_SUPPLEMENT: Lactobacillus gasseri DSM 27123|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laser Fluorescence in Cancer Surgical Treatment
Status: UNKNOWN
Conditions: Esophageal Cancer|Gastric Cancer|ColoRectal Cancer|Prostatic Neoplasms|Uterine Cancer|Head and Neck Cancer|Breast Neoplasm
Interventions: DEVICE: Green indocianine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessement of a Novel Approach to Ultrasound-guided Brachial Plexus Blockade
Status: UNKNOWN
Conditions: Nerve Block
Interventions: PROCEDURE: Ultrasound guided brachial plexus blockade|DRUG: local anaesthetic injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesia Regimens Following Trans-sphenoidal Surgery for Pituitary Tumors
Status: COMPLETED
Conditions: Pituitary Tumor|Pain
Interventions: DRUG: IV Caldolor|DRUG: IV Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Subchondroplasty® Knee RCT
Status: COMPLETED
Conditions: Bone Marrow Edema|Knee Pain Chronic|Knee Osteoarthritis|Osteoarthritis, Knee|Osteoarthritis
Interventions: PROCEDURE: Subchondroplasty with Arthroscopy|PROCEDURE: Arthroscopy Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Auto-adjusted Continuous Positive Airway Pressure for Long-term Treatment of Sleep Apnea
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: constant CPAP devices|DEVICE: automatic CPAP devices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Arm Study of Azacitidine and Venetoclax for Treatment of Newly Diagnosed Fit Acute Myeloid Leukemia Patients
Status: RECRUITING
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Azacitidine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of Osseous Integration in ACL Reconstruction Comparing Tightrope vs Interference Screw Fixation
Status: COMPLETED
Conditions: ACL - Anterior Cruciate Ligament Rupture
Interventions: DEVICE: Biocomposite intereference screw femoral tunnel fixation|DEVICE: Endobutton (Tightrope) femoral tunnel fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Dry Needling and Classic Physiotherapy Programs in The Patients Suffering From Chronic Low Back Pain Caused by Lumbar Disc Hernia
Status: COMPLETED
Conditions: Metabolic Syndrome|Physical Activity|Quality of Life
Interventions: OTHER: Dry Needling Application|OTHER: Classic Physiotherapy Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Evogliptin on Albuminuria in Patients With Type 2 Diabetes and Renal Insufficiency
Status: COMPLETED
Conditions: Type2 Diabetes Mellitus|Albuminuria|Renal Insufficiency
Interventions: DRUG: Evogliptin|DRUG: Linagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Watchful Waiting Versus Repair of Oligosymptomatic Incisional Hernias
Status: COMPLETED
Conditions: Incisional Hernia
Interventions: OTHER: Watchful waiting|PROCEDURE: Hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Wearable Activity Trackers for Detection of TOXicity in People Receiving Systemic Anticancer Treatment
Status: UNKNOWN
Conditions: Lung Cancer, Small Cell|Pancreatic Cancer|Gastric Cancer|Oesophageal Cancer|Lung Cancer, Nonsmall Cell|Lung Cancer Metastatic
Interventions: DEVICE: Wearable activity tracker - FitBit
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Paraneural Sheath & Fascial Compartments Surround Brachial Plexus at Supraclavicular Fossa During Selective Trunk Block
Status: COMPLETED
Conditions: Musculoskeletal Diseases or Conditions
Interventions: PROCEDURE: Ultrasound guided Selective trunk block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anti-Inflammatory Efficacy of Ginger Containing Dentifrice in the Control of Biofilm Induced Gingivitis
Status: COMPLETED
Conditions: Gingivitis
Interventions: DRUG: Capitano zenzero toothpaste|DRUG: Colgate total toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Patritumab With Cetuximab and a Platinum Agent for Squamous Cell Carcinoma (Cancer) of the Head and Neck (SCCHN )
Status: TERMINATED
Conditions: Head and Neck Neoplasms
Interventions: DRUG: Patritumab|DRUG: Cetuximab|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sub vs Trans-umbilical Incision: A Patient's Satisfaction-centered Trial
Status: COMPLETED
Conditions: Patient Satisfaction|Surgical Wound|Incision|General Surgery
Interventions: PROCEDURE: Transumbilical incision|PROCEDURE: Subumbilical incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Moderately Hypofractionated Photon and Proton Chemoradiotherapy as Definitive or Neoadjuvant Therapy in Non-metastatic Pancreas Cancer With Assessment of Treatment Response Utilizing Molecular Biomarkers
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer
Interventions: RADIATION: Moderately Hypofractionated RT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Incentive Spirometry in Non-critically Ill Hospitalized Patients With Acute Respiratory Failure
Status: UNKNOWN
Conditions: Pulmonary Complication|Dyspnea|Pneumonia|COPD|CHF|Atelectasis|PE
Interventions: BEHAVIORAL: Incentive Spirometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PMCF Study to Evaluate Performance and Safety of "Optrex Double Action Soothing and Lubricating Drops"
Status: COMPLETED
Conditions: Allergic Conjunctivitis|Dry Eye|Dry Eye Disease
Interventions: DEVICE: Eye drops for itchy and water eyes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebellar iTBS Mode Transcranial Magnetic Stimulation for the Treatment of Alzheimer's Disease
Status: RECRUITING
Conditions: Transcranial Magnetic Stimulation|Alzheimer Disease|Magnetic Resonance Imaging|Electroencephalogram
Interventions: DEVICE: transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exercise Intervention on Insulin Resistance in Non-alcoholic Fatty Liver Disease (NAFLD)
Status: UNKNOWN
Conditions: Non Alcoholic Fatty Liver Disease
Interventions: BEHAVIORAL: Unsupervised exercise training|BEHAVIORAL: Supervised exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole Body Vibration Training Among Older People Using Sheltered Housing
Status: TERMINATED
Conditions: Falls|Physical Performance|Fear of Falling
Interventions: BEHAVIORAL: Whole body vibration training|BEHAVIORAL: Wellness group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Pharmacodynamics and Safety Evaluation of SAR279356 in Intensive Care Unit Mechanically Ventilated Patients
Status: TERMINATED
Conditions: Infection Prophylaxis
Interventions: DRUG: SAR279356|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Concurrent Pemetrexed, Cisplatin and Radiation Therapy in Patients With Stage IIIA/B Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Pemetrexed Phase 1|DRUG: Cisplatin Phase 1|PROCEDURE: Radiation Therapy|DRUG: Pemetrexed Phase 2|DRUG: Cisplatin Phase 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Skin Repair by Topical Estrogen
Status: COMPLETED
Conditions: Skin Wrinkling
Interventions: DRUG: Topical 17-beta estradiol in ethanol/propylene glycol (ETOH/PG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Transcranial Direct Current Stimulation on Sensory Integration
Status: UNKNOWN
Conditions: Diabetic Polyneuropathy
Interventions: DEVICE: transcranial direct current stimulation and traditional physical therapy program|OTHER: designed physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: the Investigation Into Beneficial Effects of High-dose Interferon Beta 1-a, Compared to Low-dose Interferon Beta 1-a in Moderate to Severe Covid-19
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: High dose Interferon-beta 1a|DRUG: Lopinavir/Ritonavir|DRUG: Low dose Interferon-beta 1a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Armodafinil in Treating Fatigue Caused By Radiation Therapy in Patients With Primary Brain Tumors
Status: COMPLETED
Conditions: Brain Tumors|Nervous System Tumors|Cognition Disorders|Fatigue
Interventions: DRUG: Armodafinil|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CELECOXIB Plasma and Cerebral Spinal Fluid Pharmacokinetics in Children
Status: RECRUITING
Conditions: Pharmacokinetics of Celecoxib in Children
Interventions: DRUG: Celecoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oxytocin and Social Cognition in Frontotemporal Dementia
Status: COMPLETED
Conditions: Frontotemporal Dementia|Pick's Disease
Interventions: DRUG: intranasal oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Follow-Up in Patients With Prostate Cancer After Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer Survivor|Prostate Carcinoma
Interventions: OTHER: Educational Intervention|OTHER: Laboratory Biomarker Analysis|OTHER: Long-term Follow-up|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Intraoperative Muscle Relaxation Depth on Postoperative Sore Throat and Hoarseness After General Anesthesia
Status: UNKNOWN
Conditions: Sore Throat
Interventions: DRUG: Rocuronium(deep)|DRUG: Rocuronium(moderate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Safety and Tolerability of PGV001-based Personalized Multi-peptide Vaccines in the Adjuvant Setting.
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: PGV-001|BIOLOGICAL: Poly-ICLC|BIOLOGICAL: CDX-301
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Iron and Pollen Allergy in Women
Status: COMPLETED
Conditions: Allergy Pollen|Healthy
Interventions: DIETARY_SUPPLEMENT: ImmunoBon|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Violence Prevention Strategies to Prevent and Reduce Community Levels of Youth Violence
Status: ENROLLING_BY_INVITATION
Conditions: Violence|Exposure to Violent Event|Adolescent Behavior
Interventions: BEHAVIORAL: PAR - the SEED Method|BEHAVIORAL: PAR-Youth Voices|BEHAVIORAL: Emerging Leaders hospital-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Platform Study of Belantamab Mafodotin as Monotherapy and in Combination With Anti-cancer Treatments in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Belantamab mafodotin|DRUG: GSK3174998|DRUG: Feladilimab|DRUG: Nirogacestat|DRUG: Dostarlimab|DRUG: Isatuximab|DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Describe The Effect Of Impaired Hepatic Function Of The Pharmacokinetics Of Palbociclib
Status: COMPLETED
Conditions: Healthy, Hepatic Insufficiency
Interventions: DRUG: Palbociclib 75 mg Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: VisionRT-based Deep Inspiration Breath-hold (DIBH) Respiratory Motion Management Strategy, A Pilot Study for Thoracic and Abdominal Tumors
Status: UNKNOWN
Conditions: Thoracic Cancer|Abdominal Cancer
Interventions: DEVICE: Tidal volume measured by spirometer and DIBH surface from CT image
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Bioavailability of Hesperidine and Narirutin From Orange Juice to Identify Metabotypes in Hypertension
Status: COMPLETED
Conditions: Blood Pressure|Hypertension
Interventions: OTHER: Orange juice rich in hesperidin and narirutin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Umbilical Cord Mesenchymal Stem Cell for Liver Cirrhosis Patient Caused by Hepatitis B
Status: UNKNOWN
Conditions: Liver Cirrhoses
Interventions: BIOLOGICAL: Allogeneic Umbilical Cord Mesenchymal Stem Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 2940nm Er:YAG Laser Versus Benzoyl Peroxide Gel for the Treatment of Inflammatory Acne
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DEVICE: 2940 nm Er:YAG laser (DualisXS M002-2A, Fotona®, Fotona d.d, Ljubljana, Slovenia)|DRUG: Benzoyl Peroxide gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Intervention to Prevent Poor Psychosocial Outcomes in Living Donors
Status: COMPLETED
Conditions: Living Donation
Interventions: BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Healthy Lifestyles Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Computer-aided Diagnosis of Ocular Diseases Based on Corneal Biomechanics
Status: COMPLETED
Conditions: Corneal Ectasia|Corneal Disease|Corneal Astigmatism|Keratoconus|Glaucoma|Open Angle Glaucoma|Normal Tension Glaucoma
Interventions: DIAGNOSTIC_TEST: Corneal biomechanics (Corvis ST, Oculus, Wetzlar, Germany)|DIAGNOSTIC_TEST: Corneal topography and tomography (Pentacam, Oculus, Wetzlar, Germany)|DIAGNOSTIC_TEST: Optic nerve head measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MRSA Colonization and Control in the Dallas County Jail
Status: COMPLETED
Conditions: Methicillin-resistant Staphylococcus Aureus|Skin Diseases, Infectious|Soft Tissue Infections
Interventions: OTHER: Chlorhexidine|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Decitabine and Bortezomib in Treating Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Recurrent Adult Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: bortezomib|DRUG: decitabine|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of SMS Reminder on Weight Loss, as Part of a Health Pathway in Patients With Prediabetes (PREDIABCOACH)
Status: NOT_YET_RECRUITING
Conditions: PreDiabetes
Interventions: OTHER: SMS reception
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial on the Use of Autologous Bone Marrow Stem Cells in Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: PROCEDURE: Laminectomy and bone marrow stem cells transplantation|PROCEDURE: Autologous bone marrow cells collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Response to Treatment of Osteoporosis With Oral Bisphosphonates in Patients With Muscular Dystrophy
Status: COMPLETED
Conditions: Osteoporosis|Muscular Dystrophy|Cystic Fibrosis
Interventions: DRUG: Bisphosphonate treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Pharmacist-led Medication Reconciliation Service Benefits in Hospitalised Medical Patients
Status: TERMINATED
Conditions: Medication Reconciliation
Interventions: PROCEDURE: Pharmacist-led Medication Reconciliation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Low-dose Albumin Solution in SBP: a Randomized Double-blind Pilot Study
Status: UNKNOWN
Conditions: Renal Impairment|All Cause Mortality
Interventions: DRUG: Albumin|DRUG: Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platysma Trial - Platysma Suturing Versus no Sutures for Wound Closure After Primary Thyroid Surgery
Status: COMPLETED
Conditions: Thyroid Disease
Interventions: PROCEDURE: platysma suture|PROCEDURE: no platysma suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT