pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intravenous Cannulation In Children During Sevoflurane Induction
Status: COMPLETED
Conditions: Catheterization
Interventions: OTHER: Difficulty of catheterization in group 60 s|OTHER: Difficulty of catheterization in group 90 s|OTHER: Difficulty of catheterization in group 120 s
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of 3D Printed Composite Resin Crowns With Stainless Steel Crowns
Status: NOT_YET_RECRUITING
Conditions: Carious Teeth
Interventions: PROCEDURE: 3D Printed Prefabricated Composite Resin Crown Group|PROCEDURE: Prefabricated stainless steel crown group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Polytraumatisms With Corticoids
Status: COMPLETED
Conditions: Polytraumatism
Interventions: DRUG: hydrocortisone|DRUG: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Glucocorticoids on Mortality and Renal Function in Patients With Acute Decompensated Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: glucocorticoid|DRUG: standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MK-4827 in Combination With Standard Chemotherapy in Participants With Advanced Solid Tumors (MK-4827-008 AM1)
Status: TERMINATED
Conditions: Cancer: Solid Tumors
Interventions: DRUG: MK-4827|DRUG: carboplatin|DRUG: paclitaxel|DRUG: liposomal doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reproductive Hormonal Alterations in Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Cetrorelix|DRUG: Gonadorelin-GnRH|DRUG: Recombinant LH|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Pharmacokinetics, Safety, and Tolerability Study of the Autoinjector and Pre-filled Syringe of SB4 in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Diastolic dYsfunctioN AssessMent in critICally Ill Patients
Status: UNKNOWN
Conditions: Critical Illness|Diastolic Dysfunction|Diastolic Heart Failure|Weaning Failure|Mechanical Ventilation Complication
Interventions: DIAGNOSTIC_TEST: Bedside Echocardiography|PROCEDURE: Spontaneuos breathing trial|DIAGNOSTIC_TEST: Bedside Echocardiography_1|DIAGNOSTIC_TEST: Bedside Echocardiography_2|DIAGNOSTIC_TEST: Bedside Echocardiography_3|DIAGNOSTIC_TEST: Bedside Echocardiography_4
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pembrolizumab in Pre Neoplastic High Grade HPV-related Vulvar and Cervical Lesions
Status: UNKNOWN
Conditions: Cervical, Vaginal and Vulval Inflammatory Diseases
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GDS Muscle and Articulation Chain Treatment for Chronic LBP and Spinal Stenosis
Status: COMPLETED
Conditions: Low Back Pain, Recurrent|Degenerative Disc Disease
Interventions: BEHAVIORAL: Muscle and articulation chains GDS method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effectiveness of Environmental Enrichment-Based Intervention in Preterm Infants
Status: COMPLETED
Conditions: Preterm|Motor|Development, Infant|Therapy
Interventions: OTHER: HEP|OTHER: Traditional Phsical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Hemostasis by Soft Coagulation Using Endoscopic Hemostatic Forceps for Acute Peptic Ulcer Bleeding
Status: COMPLETED
Conditions: Active Peptic Ulcer Disease/GI Bleeding
Interventions: DEVICE: epinephrine injection plus soft coagulation using hemostatic forceps|DEVICE: epinephrine injection plus argon plasma coagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Performance of a New Coating for Urinary Intermittent Catheters
Status: COMPLETED
Conditions: Intermittent Urethral Catheterization
Interventions: DEVICE: ZN-D catheter|DEVICE: ZN-C catheter|DEVICE: SpeediCath catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of TRILACICLIB in Chinese Patients With Extensive-stage Small Cell Lung Cancer (ES-SCLC) for Chemotherapy-induced Myelosuppression, Antitumor Effects of Combination Regimens, and Safety in a Real-world Study
Status: COMPLETED
Conditions: Extensive-stage Small-cell Lung Cancer
Interventions: DRUG: Trilaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimized Strategy for Diabetic Patients With Critical Limb Ischemia(Part I)
Status: UNKNOWN
Conditions: Vascular Diseases|Diabetes
Interventions: DEVICE: femoral-popliteal bypass|DEVICE: stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TD-1607 MAD Study in Healthy Subjects
Status: COMPLETED
Conditions: Infections|Bacterial Infections
Interventions: DRUG: TD-1607|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain Control After Periarticular Injection During Total Knee Arthroplasty
Status: TERMINATED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Ropivacaine|DRUG: Ketorolac|DRUG: Clonidine|DRUG: Epinephrine|DRUG: 0.9% sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Needles (ProCore vs EchoTip) for the Diagnosis of Pancreatic Solid Mass Under EUS
Status: COMPLETED
Conditions: Pancreatic Tumor|Fine Needle Aspiration|Endoscopic Ultrasonography
Interventions: PROCEDURE: Puncture with fine needle aspiration under endoscopic ultrasonographic control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Optimal MTX Dose With Folic Acid Randomized Case-control Trial
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: MTX|DRUG: Folic Acid|DRUG: DMARDs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Safety and Efficacy of Itopride Hydrochloride (HCl) in Patients Suffering From Functional Dyspepsia
Status: COMPLETED
Conditions: Dyspepsia
Interventions: DRUG: Itopride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase IIIb Study of DuoTrav to Treat Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Travoprost 0.004%/timolol 0.5% ophthalmic solution|DRUG: Travoprost ophthalmic solution, 0.004%|DRUG: Timolol maleate ophthalmic solution, 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Nerve Block vs Spinal Anesthesia in Patients With Femur Fracture
Status: COMPLETED
Conditions: Femur Fracture|Peripheral Nerve Block|Spinal Anesthesia
Interventions: PROCEDURE: Spinal anesthesia|PROCEDURE: Peripheral nerve blocks|DRUG: Anesthesiological mixtures (Spinal anesthesia)|DRUG: Anesthesiological mixtures (Peripheral nerve block)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Recovery, Excretion, and Pharmacokinetics of 14C-GSK2248761 Administered as an Oral Suspension to Healthy Adult Subjects
Status: WITHDRAWN
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: 200mg [14C]- GSK2248761
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Study of Oxaliplatin and Capecitabine in Unresectable Metastatic Hepatocellular Cancer
Status: TERMINATED
Conditions: Liver Cancer|Hepatocellular Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Periurethral Pro-ACTTM Balloons vs Retrourethral AdvanceXP(TM) Male Sling for Post-prostatectomy Incontinence
Status: TERMINATED
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: AdvanceXP Male sling device|DEVICE: Pro-ACT balloon device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of 7 Versus 21 Home-delivered Medically Tailored Meals to Improve Malnutrition Risk in Malnourished Patients With Heart Failure
Status: RECRUITING
Conditions: Heart Failure|Malnutrition
Interventions: OTHER: 7 versus 21 medically tailored meals per week
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Procalcitonin in Early Antibiotic Interruption in Patient With Bacterial Pulmonary infeCtion and Acute Heart Failure
Status: COMPLETED
Conditions: Respiratory Tract Infections|Pneumonia, Bacterial|Heart Failure
Interventions: OTHER: Interruption of antibiotic treatment due to PCT measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TENS Unit To Decrease Pain After Laminaria Insertion
Status: NOT_YET_RECRUITING
Conditions: Second Trimester Abortion
Interventions: DEVICE: Transcutaneous Electrical Nerve Stimulation (TENS) unit|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Topical Crisaborole in Patients With Alopecia Areata
Status: WITHDRAWN
Conditions: Alopecia Areata
Interventions: DRUG: Crisaborole Topical Ointment|DRUG: Placebo Topical Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical-Site Infection After Laparoscopic Right Colectomy
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: PROCEDURE: Laparoscopic right colectomy with intracorporeal anastomosis (IA)|PROCEDURE: Laparoscopic right colectomy with extracorporeal anastomosis (EA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessing Mobile Apps for Adult ADHD
Status: RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DEVICE: UC-A|DEVICE: UC-N
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ofatumumab in Nodular Lymphocyte Predominant Hodgkin Lymphoma (NLPHL)
Status: COMPLETED
Conditions: Relapsed NLPHL
Interventions: DRUG: Ofatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food Study of Paroxetine Hydrochloride Tablets 40 mg and Paxil® Tablets 40 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Paroxetine hydrochloride 40 mg tablet|DRUG: Paxil® 40 mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Breathing Exercises and Upper Limb Endurance Exercises in Pregnant Women Presented With Physiological Dyspnea
Status: NOT_YET_RECRUITING
Conditions: Pregnancy Related|Dyspnea
Interventions: BEHAVIORAL: breathing exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Double-blind Ipragliflozin Add-on Study in Japanese Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Sitagliptin (MK-0431J-843)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Ipragliflozin|DRUG: Placebo|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lidocaine for Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetes|Peripheral Neuropathy|Pain
Interventions: DRUG: lidocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Antidepressant Effect of Repetitive Transcranial Magnetic Stimulation (rTMS)Compared to ECT
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: PROCEDURE: Right prefrontal lowfrequency ( 1 hz) rTMS.|PROCEDURE: Electroconvulsive therapy (ECT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lebrikizumab (LY3650150) in Adult and Adolescent Participants With Moderate-to-Severe Atopic Dermatitis Previously Treated With Dupilumab
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: Lebrikizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance (MR) Spectroscopy and Diffusion Tensor Imaging in Determining Brain Injury and Subsequent Clinical Outcome in Patients of Moderate Brain Trauma
Status: WITHDRAWN
Conditions: Brain Trauma
Interventions: OTHER: Conventional MRI of the brain|OTHER: MR spectroscopy (MRS)|OTHER: MR Diffusion Tensor Imaging (DTI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prophylaxis of Hepatitis B Virus Recurrence After Liver Transplantation
Status: UNKNOWN
Conditions: Liver Transplantation|Hepatitis B
Interventions: DRUG: lamivudine adefovir entecavir HBIG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Atheroma Reduction With Chloroquine in Patients With the Metabolic Syndrome (ARCH-MS)
Status: COMPLETED
Conditions: Metabolic Syndrome X|Overweight|Hypertension|Dyslipidemias|Prediabetic State
Interventions: DRUG: Chloroquine|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Between Different Two Self-Expanding Nitinol Stents For The Atherosclerotic Femoro-Popliteal Arterial Disease
Status: WITHDRAWN
Conditions: Arterial Disease|Atherosclerosis
Interventions: DEVICE: S.M.A.R.T CONTROL Stent|DEVICE: Complete SE Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Eplivanserin Treatment for Sleep Maintenance Insomnia Followed by Optional Extension up to 1 Year
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders|Insomnia
Interventions: DRUG: eplivanserin (SR46349)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of CPAP in Severe Therapy-resistant Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: Continuous Positive Airway Pressure (CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Hypoalgesic Effects of Low Load Blood Flow Restriction Training (BFRT)
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: Blood flow restriction training|OTHER: Sham Blood flow restriction training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peri-implant Bone Formation of Grafted Sites Around Hydrophilic and Non-hydrophilic Dental Implants
Status: NOT_YET_RECRUITING
Conditions: Partially Edentulous Maxilla|Partially Edentulous Mandible
Interventions: DEVICE: Placement of a "Straumann® Bone Level Tapered implant SLActive®" (hydrophilic surface)|DEVICE: Placement of a "Straumann® Bone Level Tapered implant SLA®" (hydrophobic surface)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability and Pharmacokinetics Study of STP1 in a Subgroup of Patients With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: STP1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Second Generation Antipsychotics in First Episode Psychosis Patients: 3-year Follow-up
Status: UNKNOWN
Conditions: Schizophrenia|Psychotic Disorders|Psychosis
Interventions: DRUG: Aripiprazole|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PTSD Help - a Randomized Controlled Trial of a PTSD Mobile Health App
Status: UNKNOWN
Conditions: PTSD|Post Traumatic Stress Disorder
Interventions: DEVICE: mHealth intervention, PTSD Help app.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Nonsurgical Periodontal Therapy (NSPT) on Rheumatoid Arthritis Subjects With Periodontitis
Status: RECRUITING
Conditions: Periodontitis|Rheumatoid Arthritis
Interventions: PROCEDURE: Nonsurgical periodontal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Age Assessment in Children Using Ultrasound Compared to Wrist X-ray
Status: UNKNOWN
Conditions: Short Stature|Growth Disorders
Interventions: DEVICE: SonicBone Ultrasound|DEVICE: Wrist X-ray
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: To Compare The Efficacy Of N -Acetylcysteine and Standard Therapy Versus Standard Therapy In The Prevention Of Ischemic Hepatitis And Survival Post Upper GI Bleed
Status: COMPLETED
Conditions: Ischemic Hepatitis
Interventions: DRUG: Standard Care + NAC (N -ACETYLCYSTEINE)|DRUG: Standard Care (in control arm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chlorhexidine Gluconate Versus Mupirocin Ointment in the Prevention of Peritoneal Dialysis-Related Infection
Status: UNKNOWN
Conditions: End Stage Renal Disease|Peritoneal Dialysis
Interventions: OTHER: Chlorhexidine gluconate-soaked cloths|OTHER: Normal saline|OTHER: mupirocin ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Leg Muscular Activity Using MRI and 11C-acetate PET/MRI. Pilot Study
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: Magnetic Resonance Imaging|OTHER: Magnetic Resonance combined with Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Contribution of the CEST Sequence in the Characterization of Radionecrosis of Brain Metastases of Pulmonary Origin
Status: RECRUITING
Conditions: Brain Metastases|Radionecrosis|Pulmonary Cancer
Interventions: RADIATION: MRI with CEST sequence, IVIM and ASL sequence
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Chemotherapy in Treating Patients With Solid Tumors
Status: COMPLETED
Conditions: Bladder Cancer|Breast Cancer|Colorectal Cancer|Esophageal Cancer|Head and Neck Cancer|Kidney Cancer|Lung Cancer|Ovarian Cancer|Prostate Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: oblimersen sodium|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Vaccine Hyporesponse in Healthy Elderly Participants (MK-0000-131 AM2)
Status: COMPLETED
Conditions: Vaccine Response Impaired
Interventions: BIOLOGICAL: Tetanus & Diphtheria booster vaccine (Td)|BIOLOGICAL: TwinrixTM [Hepatitis A Inactivated & Hepatitis B (Recombinant) Vaccine]|BIOLOGICAL: Dukoral® Traveler's Diarrhea Vaccine (WC/rBS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Compare Efficacy and Safety of Repeated Courses of Rituximab to That of Maintenance Mycophenolate Mofetil Following Single Course of Rituximab Among Children With Steroid Dependent Nephrotic Syndrome
Status: UNKNOWN
Conditions: Steroid-Dependent Nephrotic Syndrome
Interventions: DRUG: Rituximab|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intranasal Neuropeptide on Emotion Perception in Trait Anxiety
Status: COMPLETED
Conditions: Social Intelligence
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of TAK-861 in Participants With Narcolepsy Type 1
Status: COMPLETED
Conditions: Narcolepsy Type 1
Interventions: DRUG: TAK-861|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Nafamostat on Postreperfusion Syndrome (PRS)
Status: COMPLETED
Conditions: Liver Transplantation|Postreperfusion Syndrome
Interventions: DRUG: Nafamostat|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Improving Quality Based on the Joint Registry
Status: COMPLETED
Conditions: Registries|Quality Improvement|Hip Arthropathy|Knee Arthropathy|Hospital Performance
Interventions: OTHER: Monthly feedback, education and linking hospitals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Morphometric Study of the Muscles of the Skin in MRI 3 Tesla in Patients With Facial Paralysis.
Status: RECRUITING
Conditions: Facial Paralysis
Interventions: OTHER: Carry out the morphometric evaluation of the muscles of the skin, especially the large zygomatic muscle, in patients with sequelae of facial paralysis|OTHER: Carry out the morphometric evaluation of the muscles of the skin, especially the large zygomatic muscle, in healthy subjects
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lentiviral Gene Therapy for X-Linked Chronic Granulomatous Disease (X-CGD)
Status: WITHDRAWN
Conditions: Granulomatous Disease, Chronic, X-linked, Variant
Interventions: GENETIC: pCCLchimGp91s lentiviral vector transduced CD34+ cells infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Three Part SAD, MAD & Cross-Over Study of ZP-059 in Healthy and Asthmatic Subjects
Status: COMPLETED
Conditions: Allergic Bronchopulmonary Aspergillosis
Interventions: DRUG: Voriconazole inhaled|DRUG: oral voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Physical Therapy in Pain and Posture of Fibromyalgia Patients
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: Global postural reeducation|OTHER: Segmental muscle stretching exercises|OTHER: Cognitive behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Neurobiological Predictors of Response to Non-invasive Neurostimulation and Genetic Susceptibility to Dementia in Patients With Amnestic Mild Cognitive Impairment
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: Transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myofascial Release With and Without METS of Gluteus Maximus and Tensor Fascia Lata in ITB Syndrome
Status: COMPLETED
Conditions: Iliotibial Band Syndrome
Interventions: OTHER: Muscle energy technique of gluteus maximus and tensor fascia lata|OTHER: Myofascial release of iliotibial band syndrome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LGK974 in Patients With Malignancies Dependent on Wnt Ligands
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer|BRAF Mutant Colorectal Cancer|Melanoma|Triple Negative Breast Cancer|Head and Neck Squamous Cell Cancer|Cervical Squamous Cell Cancer|Esophageal Squamous Cell Cancer|Lung Squamous Cell Cancer
Interventions: DRUG: LGK974|BIOLOGICAL: PDR001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Exenatide vs. Biphasic Insulin Aspart 30 on Glucose Variability in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Exenatide|DRUG: Biphasic insulin Aspart 30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture in Distal Radius Fracture Patients
Status: COMPLETED
Conditions: Colles´ Fracture|Radius Fracture
Interventions: PROCEDURE: Rehabilitation|DEVICE: Low Lever Laser acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Neuromuscular Electrical Stimulation on Muscle Mass and Strength in Critically Ill Patients After Cardiothoracic Surgery
Status: COMPLETED
Conditions: Neuromuscular Electrical Stimulation|Intensive Care Unit Acquired Weakness|Muscle Wasting|Muscle Loss
Interventions: DEVICE: Compex 3 Professional (CefarCompex Medical AB) stimulator|DEVICE: sham-stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Identifying and Treating Arousal Related Deficits in Neglect and Dysphagia
Status: COMPLETED
Conditions: Spatial Neglect|Dysphagia
Interventions: DRUG: Modafinil|DRUG: Placebo|BEHAVIORAL: Baseline|BEHAVIORAL: CPS|BEHAVIORAL: Post CPS|BEHAVIORAL: Follow up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Platelet Rich Plasma Injections for Post Traumatic Greater Occipital Neuralgia
Status: COMPLETED
Conditions: Occipital Neuralgia|Headache
Interventions: BIOLOGICAL: Autologous Platelet Rich Plasma Injection|DRUG: Depo-Medrol and lidocaine|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Prothrombin Complex Concentrate in Patients Admitted in Emergency Care Units for Severe Bleeding While Receiving Oral Anticoagulants
Status: COMPLETED
Conditions: Emergency Care for Severe Bleeding While on Anticoagulants
Interventions: OTHER: Expert eCRF|OTHER: Prothrombin Complex Concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A First-in-Human Study of JAB-3068 (SHP2 Inhibitor) in Adult Patients With Advanced Solid Tumors in China
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer|Head and Neck Cancer|Esophageal Cancer|Other Metastatic Solid Tumors
Interventions: DRUG: JAB-3068
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adult Respiratory Failure Intervention Study Africa
Status: COMPLETED
Conditions: Acute Respiratory Failure With Hypoxia|Acute Respiratory Distress Syndrome|Acute Lung Injury
Interventions: PROCEDURE: HFNC|PROCEDURE: CPAP|PROCEDURE: Standard Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Painless Sharp Wound Debridement With Lidocaine-23%-Tetra-caine-7% Gel Versus EMLA 5% Cream
Status: RECRUITING
Conditions: Ulcus Cruris|Ecthyma|Ulcer, Leg|Ulcer Venous
Interventions: DRUG: IMP2 (lidocaine-23%-tetracaine-7% gel)|DRUG: IMP1 (EMLA 5% cream)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Hypotension Prediction Index in Free Flap Transplant in Head and Neck Surgery.
Status: NOT_YET_RECRUITING
Conditions: Hypotension|Head and Neck Cancer|Perioperative Complication|Postoperative Complications
Interventions: DEVICE: Hypotension Prediction Index
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Infrared Bioeffect System for the Treatment of Cutaneous Warts
Status: COMPLETED
Conditions: Cutaneous Warts|Human Papilloma Virus
Interventions: DEVICE: liquid nitrogen|DEVICE: controllable infrared bioeffect system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Oxygen Therapy Delivered by Systems Using Oxygen-Saving Valves in COPD Patients
Status: RECRUITING
Conditions: LUNG DISEASES, OBSTRUCTIVE
Interventions: DEVICE: pulse oxygen supplementation devices|DEVICE: continuous oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Single Dose Fast Release Aspirin (1000 mg) Tablet Versus Single Dose of Two 500 mg Fast Release Aspirin Tablets
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Acetylsalicylic acid (Aspirin, BAY1019036)|DRUG: Acetylsalicylic acid (Aspirin, BAY1019036)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed Plus Apatinib Maintenance Treatment in Patients With Non-squamous Non-small Cell Lung Cancer Patients Who Have Not Progressed After 4 Cycles of Induction Chemotherapy of Pemetrexed in Combination With Platinum-based Regimen
Status: WITHDRAWN
Conditions: Advanced Non-squamous Non-small-cell Lung Cancer
Interventions: DRUG: Apatinib|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SHIP-AGE: Frailty, Renal Function, and Multi-component Primary Care in Rural Mecklenburg-Western Pomerania
Status: NOT_YET_RECRUITING
Conditions: Frailty Syndrome
Interventions: DIAGNOSTIC_TEST: Multi-factorial geriatric assessment, monitoring & management systems
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate GSK Biologicals' Herpes Zoster Vaccine GSK1437173A in Human Immunodeficiency Virus (HIV)-Infected Subjects
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Herpes Zoster Vaccine GSK1437173A|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Telitacicept Study in Chinese Subjects With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Telitacicept|DRUG: standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Hyaluronic Acid and Honey in Healing of Multiple Extraction Sockets of Primary Teeth Compared to Saline
Status: UNKNOWN
Conditions: Wound Heal
Interventions: DRUG: Hyaluronic acid|DIETARY_SUPPLEMENT: honey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors
Status: COMPLETED
Conditions: Neuroblastoma|Rhabdomyosarcoma|Ewing's Sarcoma|Ewing's Tumor|Sarcoma, Ewing's|Sarcomas, Epitheliod|Sarcoma, Soft Tissue|Sarcoma, Spindle Cell|Melanoma|Malignant Melanoma|Clinical Oncology|Oncology, Medical|Pediatrics, Osteosarcoma|Osteogenic Sarcoma|Osteosarcoma Tumor|Sarcoma, Osteogenic|Tumors|Cancer|Neoplasia|Neoplasm|Histiocytoma|Fibrosarcoma|Dermatofibrosarcoma
Interventions: DRUG: nab-paclitaxel|DRUG: nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conservative Aortic Valve Surgery for Aortic Insufficiency and Aneurysms of the Aortic Root. CAVIAAR
Status: COMPLETED
Conditions: Aortic Valve Insufficiency|Aortic Aneurysm
Interventions: PROCEDURE: Remodeling procedure associated with a subvalvular aortic ring or double sub and supra-valvular aortic annuloplasty|DEVICE: Mechanical valve replacement (isolated or composite valve and graft replacement); actual surgical standard for dystrophic aortic roots
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of a IMSS Developed Phytopharmaceutical for the Treatment of Anxiety.
Status: UNKNOWN
Conditions: Generalized Anxiety Disorder
Interventions: DIETARY_SUPPLEMENT: Galphimia glauca standardized extract|DRUG: alprazolam 1mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Safety Study of SPARC1023 Alone and in Carboplatin Combination
Status: COMPLETED
Conditions: Solid Tumor in Advanced Stage
Interventions: DRUG: SPARC1023 I|DRUG: SPARC1023 II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interdisciplinary Medication Review Interventions in an Integrated Outpatient Department.
Status: COMPLETED
Conditions: Comorbidity|Multimorbidity|Drug Prescribing|Cognitive Impairment|Language Problems
Interventions: OTHER: Interdisciplinary Deprescribing and Medication Optimization Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) Associated With Systemic Chemotherapy in Women With Advanced Ovarian Cancer
Status: RECRUITING
Conditions: Metastatic Ovarian Carcinoma|Peritoneal Carcinomatosis|Stage III Ovarian Cancer|Stage IV Ovarian Cancer|Stage III Fallopian Tube Cancer|Stage IV Fallopian Tube Cancer|Metastatic Malignant Neoplasm in the Peritoneum
Interventions: DRUG: Combined PIPAC / IV chemotherapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fish Gelatin Supplement and Omega-3 Supplement in Obese or Overweight Subjects With Insulin Resistance
Status: COMPLETED
Conditions: Insulin Resistance|Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Fish gelatin and omega-3 polyunsaturated fatty acid|DIETARY_SUPPLEMENT: Omega-3 polyunsaturated fatty acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dose Intralipid Infusion Reduces Pregnancy Complications Caused by Antiphospholipid Antibody Syndrome?
Status: WITHDRAWN
Conditions: Antiphospholipid Syndrome in Pregnancy
Interventions: DRUG: Intralipid, 20% Intravenous Emulsion|DRUG: Conventional therapy of antiphospholipis syndrome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects With Sickle Cell Disease
Status: COMPLETED
Conditions: Anemia, Sickle Cell
Interventions: DRUG: Rivipansel|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Live Biotherapeutic Product MRx0518 and Pembrolizumab Combination Study in Solid Tumors
Status: TERMINATED
Conditions: Oncology|Solid Tumor|Non Small Cell Lung Cancer|Renal Cell Carcinoma|Melanoma|Bladder Cancer
Interventions: DRUG: MRx0518|DRUG: Pembrolizumab 25 MG/1 ML Intravenous Solution [KEYTRUDA]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic and Metagenomic Effects of Intestinal Microbiome Repopulation in Unexplained Atherosclerosis
Status: RECRUITING
Conditions: Atherosclerosis|Intestinal Microbiome
Interventions: BIOLOGICAL: Fecal microbial transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiation Hypofractionation Via Extended Versus Accelerated Therapy (HEAT) For Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Extended Hypofractionation Radiotherapy|RADIATION: Accelerated Hypofractionation Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mucosal Immunity Against Neisseria Gonorrhoeae After 4CMenB Vaccination
Status: COMPLETED
Conditions: Gonorrhoea
Interventions: BIOLOGICAL: Meningococcal Group B Vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Semaglutide on CD34+ EPC and Fat Derived MSC
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Semaglutide|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer
Status: RECRUITING
Conditions: Metastatic Non Small Cell Lung Cancer
Interventions: BIOLOGICAL: LN-145|BIOLOGICAL: LN-145
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Physical Activity Versus Dietary Energy Restriction on Tumour and Muscle Protein Synthesis in Prostate Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Cancer of Prostate
Interventions: BEHAVIORAL: Dietary energy restriction|BEHAVIORAL: Daily exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy Plus IM-862 in Treating Patients With Resected Stage III Ovarian Cancer or Primary Peritoneal Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: carboplatin|DRUG: oglufanide disodium|DRUG: paclitaxel|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Etanercept for the Treatment of Refractory Heel Enthesitis in Spondylarthropathy
Status: COMPLETED
Conditions: Spondylarthropathies, Enthesitis
Interventions: DRUG: Etanercept|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiopulmonary Exercise Testing to Evaluate Pulmonary AVMs With and Without Airflow Obstruction
Status: UNKNOWN
Conditions: Pulmonary Arteriovenous Malformations|Hereditary Hemorrhagic Telangiectasia|Asthma|COPD
Interventions: OTHER: Cardiopulmonary exercise test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Applicaiton of Immune Repertoire in the Diagnosis and Disease Monitoring of IgA Nephropathy
Status: UNKNOWN
Conditions: IgA Nephropathy
Interventions: DRUG: Intervention for incipient patients at low risk of disease progression|DRUG: Intervention for patients at high risk of disease progression
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Indices of Body Composition During Ultramarathon : Measure by Body Bioelectrical Impedance
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DEVICE: body bioelectrical impedance performed by Z-Métrix (class IIa) - BIOPARHOM 12 allée des lacs de garde, Savoie Technolac BP 238, 73374 Bourget du lac, France
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Study of DC Versus 5-FU/CF as Chemotherapy and Concurrent Chemoradiotherapy for Locally Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: DC|DRUG: concurrent chemoradiotherapy with 5-FU/CF|RADIATION: radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Secukinumab Compared to Ustekinumab in Subjects With Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Secukinumab|DRUG: Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Total Extraperitoneal Plasty as a Modification of Sugabecker's Operation
Status: RECRUITING
Conditions: Parastomal Hernia
Interventions: PROCEDURE: standard Sugarbecker's operation|PROCEDURE: modified Sugarbecker's operation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exercise Training and Arch Supported Insoles on Balance and Vertical Jump Performance in Football Players With Foot Pronation Deformity
Status: COMPLETED
Conditions: Foot; Pronation, Congenital
Interventions: OTHER: Using Insoles|OTHER: Foot Core Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: UM CRMC RecuR Score Pilot
Status: WITHDRAWN
Conditions: Patient Readmission|Pulmonary Disease, Chronic Obstructive|Heart Failure|Diabetes Mellitus Poor Control|Hypertension|Pneumonia
Interventions: OTHER: Standard of Care|OTHER: Enhanced Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Imaging Serotonin 5HT1A Receptors in Patients With Major Depressive Disorder
Status: WITHDRAWN
Conditions: Major Depression|Unipolar Depression|Depression|Anxiety Disorder
Interventions: OTHER: Antidepressant (SSRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Convalescent Plasma for Early Treatment of COVID-19
Status: TERMINATED
Conditions: SARS-CoV 2|COVID-19
Interventions: BIOLOGICAL: Convalescent Plasma (anti-SARS-CoV-2 plasma)|BIOLOGICAL: Control (albumin 5%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incretin Hormones in Type 1 Diabetes Mellitus;Effect of Metformin Treatment
Status: UNKNOWN
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT