pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Phase I Dose-Escalation Study of BMS-641988 in Patients With Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: AR Antagonist (BMS-641988)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ketoconazole Contributes to Cryptorchidism Outcome Via Modulating Macrophage Trem2
Status: RECRUITING
Conditions: Cryptorchidism
Interventions: DRUG: Ketoconazole|DRUG: Luteinizing Hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Changing Eating Behaviors of Healthy Adults Through Hypnosis
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: BEHAVIORAL: Hypnosis with amnesia suggestions|BEHAVIORAL: Hypnosis with cognitive rehearsal suggestions|BEHAVIORAL: Hypnosis with memory substitution suggestions|BEHAVIORAL: Hypnosis with induction only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of Umbilical Cord Blood Cell Transplant Into Injured Spinal Cord
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: BIOLOGICAL: Umbilical Cord Blood Mononuclear Cell|DRUG: Methylprednisolone|DRUG: Lithium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Level Laser Therapy for Better Wound Healing
Status: RECRUITING
Conditions: Surgical Scar Tissue of Cesarean Section or Vaginal Tear or Episiotomy
Interventions: DEVICE: Low-level laser therapy|DEVICE: "Fake" low-level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy
Status: COMPLETED
Conditions: Cervical Degenerative Disc Disease|Degenerative Spondylolisthesis|Spinal Stenosis
Interventions: BIOLOGICAL: NeoFuse|PROCEDURE: Allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Sting Challenge and Serological Responses to Jack Jumper Venom Immunotherapy With Inulin as Adjuvant (Jumpvax)
Status: UNKNOWN
Conditions: Ant Sting|Immunotherapy
Interventions: DRUG: Delta-inulin|BIOLOGICAL: Dose finding comparison
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tri-weekly Cisplatin Based Chemoradiation in Locally Advanced Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: DRUG: Weekly cisplatin with RT|DRUG: Tri-weekly cisplatin with RT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Torrent Pharmaceuticals Ltd's Bioequivalence Study of Torrent Pharmaceuticals Ltd's Quetiapine Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Torrent's Quetiapine Fumarate Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: A Study to Compare the NexGen LPS and LPS-Flex Knee Implants
Status: COMPLETED
Conditions: Total Knee Arthroplasty|Osteoarthritis
Interventions: DEVICE: NexGen LPS-Flex Fixed Bearing Knee|DEVICE: NexGen Legacy Posterior Stabilized Knee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Giant Cell Arteritis Treatment With Ultra-short Glucocorticoids and Tocilizumab
Status: COMPLETED
Conditions: Giant Cell Arteritis
Interventions: DRUG: Tocilizumab|DRUG: Glucocorticoids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contribution of Optical Coherence Tomography in the Endovascular Treatment of Femoral Occlusions
Status: UNKNOWN
Conditions: Superficial Femoral Artery Stenosis|Claudication|Ischemic Leg
Interventions: DEVICE: femoropopliteal revascularization for TASC C or TASC D lesion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of Bupivacaine HCl Spinal Block and EXPAREL Local Infiltration in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Bupivacaine SNB|DRUG: EXPAREL Infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Mobile App in House Staff Health and Well-being During COVID-19 Pandemic
Status: UNKNOWN
Conditions: Perceived Stress|Anxiety|Sleep Disturbance|Burnout|PTSD
Interventions: DEVICE: Calm Meditation App
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Patient Performance and Acceptance of Virtual Reality Visual Field Devices
Status: COMPLETED
Conditions: Visual Field Defect, Peripheral|Visual Field Defect, Nasal Step|Visual Field Defect, Paracentral Scotoma of Both Eyes
Interventions: OTHER: VIrtual Reality Visual Field Exam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Continuous Positive Airway Pressure and Oral Appliances Treatments in Mild Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Mild Obstructive Sleep Apnea Syndrome
Interventions: DEVICE: Continuous Positive Airway Pressure (CPAP)|DEVICE: Oral Appliance (BRD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety Study of TORIPALIMAB INJECTION Combined With Chemotherapy for Nasophapyngeal Cancer
Status: UNKNOWN
Conditions: Recurrent or Metastatic NPC
Interventions: BIOLOGICAL: TORIPALIMAB INJECTION(JS001 ) combine with chemotherapy|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Efficacy and Safety of Ragweed MATAMPL, Pollinex-R and Placebo in Patients With Ragweed Allergy
Status: COMPLETED
Conditions: Type I Hypersensitivity
Interventions: BIOLOGICAL: Ragweed MATAMPL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes of Preservation Versus Resection of Portal/Superior Mesenteric Vein During Pancreaticoduodenectomy in Pancreatic Cancer Patients Who Respond to Neoadjuvant Treatment
Status: COMPLETED
Conditions: Pancreatic Head Cancer Patients Who Underwent Surgery After Neoadjuvant Treatment
Interventions: PROCEDURE: portal/superior vein resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prophylactic Negative Pressure Wound Therapy for Patients Undergoing Incisional Hernia Repair
Status: UNKNOWN
Conditions: Incisional Hernia|Surgical Wound Infection|Surgical Site Infection|Quality of Life
Interventions: DEVICE: Negative Wound Pressure Therapy (Prevena(TM))|OTHER: Standard Wound Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Bimatoprost in Japanese Patients With Chemotherapy-Induced Eyelash Hypotrichosis
Status: COMPLETED
Conditions: Eyelash Hypotrichosis
Interventions: DRUG: bimatoprost solution 0.03%|DRUG: bimatoprost vehicle solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Do Benzodiazepines Improve the Outcome of Mechanical Physiotherapy for Lumbar Disk Prolapse
Status: COMPLETED
Conditions: Pain|Disability|Paresis
Interventions: DRUG: benzodiacepine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Take A Break - Rural
Status: RECRUITING
Conditions: Smoking|Smoking Behaviors|Smoking Cessation
Interventions: BEHAVIORAL: Take a Break plus Nicotine replacement therapy (NRT) Sampling|BEHAVIORAL: The Comparison|OTHER: Community Paramedicine Standard Plus Enhanced Implementation Program|OTHER: Community Paramedicine Standard Implementation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Predictive and Prognostic Value of Germ-line Polymorphisms in Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Metastasis
Interventions: OTHER: Blood sample for genetic analysis (Identification of germ line genetic factors that influence the risk of metastatic breast cancer)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: OTHER
Clinical trial: Gemcitabine and Oxaliplatin as Second-Line Therapy in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RP5063 in Subjects With Schizophrenia or Schizoaffective Disorder
Status: COMPLETED
Conditions: Acute Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: RP5063|DRUG: placebo|DRUG: RP5063|DRUG: RP5063|DRUG: aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of Intra-articular Hybrid Hyaluronic Acid and Steroid in Patients With Rizoarthrosis
Status: UNKNOWN
Conditions: Osteoarthritis Thumb
Interventions: DEVICE: Sinovial H-L|DRUG: Triamcinolone Acetonide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mobile Video Interpretation to Optimize Communication Across Language Barriers
Status: ENROLLING_BY_INVITATION
Conditions: Limited English Proficiency
Interventions: BEHAVIORAL: Web based educational modules|BEHAVIORAL: mobile video interpreting (mVI) access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Testing Ramipril to Prevent Memory Loss in People With Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma|Radiotherapy; Complications|Cognitive Decline|Chemoradiation
Interventions: DRUG: Ramipril
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial of CDX-1135 in Pediatric and Adult Patients With Dense Deposit Disease
Status: TERMINATED
Conditions: Dense Deposit Disease|Membranoproliferative Glomerulonephritis Type II|C3 Glomerulonephritis
Interventions: DRUG: CDX-1135
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Efficacy of Steroid Treatment of Achalasia
Status: WITHDRAWN
Conditions: Achalasia
Interventions: DRUG: Apo-Prednisone Cordorol, Detasone - Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Penicillin for the Emergency Department Outpatient Treatment of CELLulitis
Status: UNKNOWN
Conditions: Cellulitis|Wound Infection|Abscess
Interventions: DRUG: Flucloxacillin|DRUG: Phenoxymethylpenicillin|DRUG: Placebo (for phenoxymethylpenicillin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Acupuncture for Chemotherapy-induced Peripheral Neuropathy in Breast Cancer Patients
Status: COMPLETED
Conditions: Taxane-induced Peripheral Neuropathy|Chemotherapy-induced Peripheral Neuropathy (CIPN)|Early-Stage Breast Carcinoma|Stage I Breast Cancer|Stage II Breast Cancer|Stage III Breast Cancer
Interventions: PROCEDURE: Immediate Acupuncture Group|PROCEDURE: Delayed Acupuncture Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Surgical Treatment of Lower Eyelid Involutional Entropion and Dermatochalasis
Status: UNKNOWN
Conditions: Eyelid Diseases
Interventions: PROCEDURE: lower eyelid blepharoplasty , retractor plication and wedge resection|PROCEDURE: lower eyelid blepharoplasty and retractor plication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain Intensity After Using Different Instrumentation Techniques: a Randomized Clinical Study
Status: COMPLETED
Conditions: Pulpitis
Interventions: DEVICE: Reciprocating system|DEVICE: Rotational system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Post-marketing Safety Surveillance of NovoSeven® in Patients With Haemophilia and Inhibitors by Means of the UK Haemophilia Database
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A|Haemophilia B
Interventions: DRUG: activated recombinant human factor VII
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Short-term Presurgical Study to Assess Molecular Predictors of Lapatinib's Effects in Primary Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Lapatinib|DRUG: Lapatinib-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Optimize Antenatal Management of Women With Pre Term Labor Using Amniocentesis
Status: UNKNOWN
Conditions: Preterm Birth|Preterm Labor|Intra-amniotic Infection|Amniocentesis Affecting Fetus or Newborn
Interventions: DRUG: Steroid Drug|DRUG: Tocolytic Agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Pevonedistat Plus Docetaxel in Patients With Previously Treated Advanced Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Pevonedistat|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recombinant Hyaluronidase in Out-of-Hospital Setting: The EASI Access Trial
Status: COMPLETED
Conditions: Mass Casualty Incident|Dehydration
Interventions: OTHER: hypodermoclysis via recombinant hyaluronidase-facilitated subcutaneous infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3 Local Anesthetics for Spinal Anesthesia in Primary Total Hip Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis, Hip
Interventions: DRUG: isobaric bupivacaine|DRUG: hyperbaric bupivacaine|DRUG: isobaric mepivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Radiation Therapy for Glioblastoma Multiforme
Status: COMPLETED
Conditions: High Grade Glioma
Interventions: RADIATION: Low Dose Fractionated Radiation Therapy (LDFRT)|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caffeine Citrate for the Treatment of Apnea Associated With Bronchiolitis in Young Infants
Status: COMPLETED
Conditions: Bronchiolitis|Apnea|Caffeine
Interventions: DRUG: Caffeine citrate|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Usual Care Intervention Research Evaluating the Impact of a Personalized Pharmaceutical Plan on the Duration of Opioid Treatment in Non-cancerous Pain
Status: UNKNOWN
Conditions: Non-cancerous Pain|Opioid Use
Interventions: BEHAVIORAL: Admission conciliation interview|BEHAVIORAL: Discharge conciliation interview|BEHAVIORAL: Targeted pharmaceutical interview
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Consistency of Cardiac Output Measured by Pulmonary Artery Catheter and LiDCO in Cardiac Surgical Patients
Status: UNKNOWN
Conditions: Cardiac Surgery|Cardiac Output
Interventions: DIAGNOSTIC_TEST: Passive Leg Raising|DIAGNOSTIC_TEST: Dobutamine stress test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 2a Clinical Trial of ID93+GLA-SE Vaccine in BCG-vaccinated Healthy Healthcare Workers
Status: UNKNOWN
Conditions: Tuberculosis
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: ID93+GLA-SE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sintilimab Plus Chidamide in the Treatment of Relapsed and Refractory Cutaneous T-cell Lymphoma: a Multicenter Phase II Study
Status: RECRUITING
Conditions: Cutaneous T-cell Lymphoma
Interventions: DRUG: Sintilimab|DRUG: Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intrathecal Versus Intravenous Dexmedetomidine for Prevention of Post Spinal Anesthesia Shivering
Status: UNKNOWN
Conditions: Postoperative Shivering
Interventions: DRUG: intrathecal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Preincisional Infiltrated Dexmedetomidine and Lidocaine Plus Adrenaline for Nasal Sephoplasty Surgery.
Status: COMPLETED
Conditions: Surgery|Pain
Interventions: DRUG: Dexmedetomidine|DRUG: Lidocaine|DRUG: Adrenaline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study Comparing the Safety and Efficacy of Everolimus With Other Medicines in Recipients of ECD/DCD Kidneys
Status: TERMINATED
Conditions: Delayed Graft Function
Interventions: DRUG: Everolimus|DRUG: Tacrolimus|DRUG: Mycophenolate mofetil (MMF/MPA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sacituzumab Govitecan +/- Pembrolizumab In HR+ / HER2 - MBC
Status: ACTIVE_NOT_RECRUITING
Conditions: Invasive Breast Cancer|Metastatic Breast Cancer|HR-Positive Breast Cancer|HER2-negative Breast Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Sacituzumab Govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Postoperative Pain After Abdominal Surgery for Gynecological Diseases
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DEVICE: Acupuncture|DEVICE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fractional Laser Assisted Delivery of Anesthetics III
Status: COMPLETED
Conditions: Local Anesthesia of the Skin
Interventions: DEVICE: Fractional CO2 laser, 2.5 mJ, 5% density|DEVICE: Fractional CO2 laser, 2.5 mJ, 15% density|DEVICE: Fractional Er:YAG laser, 9 mJ, 5% density|DEVICE: Fractional Er:YAG laser, 9 mJ, 15% density|DEVICE: Fractional CO2 laser, 50 mJ, 5% density|DRUG: AHES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Acute Neurobehavioral Program for Improving Functional Status After TBI
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: FANCI|BEHAVIORAL: FANCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 12 Weeks of Resistance Band Exercise Impacts on Metabolic Syndrome Progression in Postmenopausal Women
Status: COMPLETED
Conditions: Metabolic Syndrome|Dyslipidemias|Insulin Resistance|Hypertension
Interventions: OTHER: No exercise intervention group|BEHAVIORAL: Resistance band exercise intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Therapeutic Education of Chronic Renal or Renal Transplant Patient in the Management of EPO Injections
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic|Organ Graft
Interventions: DEVICE: Patients with injections of ESA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1b/2 Study of Safety and Efficacy of Rociletinib in Combination With MPDL3280A in Patients With Advanced or Metastatic EGFR-mutant NSCLC
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Rociletinib|DRUG: MPDL3280A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ericksonian Hypnosis Versus CBT for Prolonged Grief
Status: COMPLETED
Conditions: Prolonged Grief Symptoms
Interventions: BEHAVIORAL: Ericksonian Hypnosis|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Effects of Plyometric and Isotonic Strengthening Exercises of Lower Extremity Among Field Tennis Players
Status: COMPLETED
Conditions: Lower Extremity Problem
Interventions: OTHER: Plyometric strengthening exercises|OTHER: Isotonic strengthening exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: A Study Examining the Use of Vaginal Nifedipine With Pelvic Floor Physical Therapy for Levator Myalgia and Pelvic Pain
Status: WITHDRAWN
Conditions: Levator Ani Syndrome
Interventions: DRUG: Nifedipine|DRUG: Placebo Ointment Base
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Atezolizumab in Combination With Bevacizumab in Spanish Patients With Unresectable or Unsuitable for Locoregional Treatments Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic-pharmacodynamic Analysis of Sugammadex for Conventional Reversal in Children
Status: COMPLETED
Conditions: Anesthesia, General|Neuromuscular Blockade
Interventions: DRUG: Sugammadex Injection 2mg/kg|DRUG: Sugammadex Injection 4mg/kg|DRUG: Sugammadex Injection 8mg/kg|DRUG: Neuromuscular reversal agent injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Reduce the Use of Chemotherapy in Postmenopausal Patients With ER-positive and HER2-positive Breast Cancer (TOUCH)
Status: COMPLETED
Conditions: Breast Cancer|Estrogen Receptor Positive Tumor|HER2-positive Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Palbociclib|DRUG: Letrozole|DRUG: Trastuzumab|DRUG: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: iCLAS™ Cryoablation System Post-Market Clinical Follow-up (PMCF) Study
Status: RECRUITING
Conditions: Atrial Fibrillation|Atrial Flutter|Paroxysmal Atrial Fibrillation|Persistent Atrial Fibrillation
Interventions: DEVICE: cryoablation procedure using the iCLAS Cryoablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Knee Brace When Combined With Viscosupplementation in the Treatment of Knee Osteoarthritis
Status: TERMINATED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Orthovisc|DEVICE: DonJoy HA lite knee brace|DEVICE: Orthovisc injections and DonJoy HA lite knee brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Natural Versus Man-Made Trans Fatty Acids on Lipoprotein Profiles: A Pilot Study
Status: COMPLETED
Conditions: Cardiovascular Disease|Diabetes|Dyslipidemia
Interventions: DIETARY_SUPPLEMENT: Man-made Trans FA|DIETARY_SUPPLEMENT: Natural Trans FA|DIETARY_SUPPLEMENT: Oleic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Cardiac Ganglionated Plexus Ablation Before Permanent Pacemaker Implantation in Patients With Sick Sinus Syndrome
Status: UNKNOWN
Conditions: Cardioneuroablation|Permanent Pacemaker Implantation|Sick Sinus Syndrome|Ganglionated Plexus
Interventions: PROCEDURE: cardiac ganglion plexus ablation(cardioneuroablation)|DEVICE: Permanent pacemaker implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intravenous Neridronic Acid in Complex Regional Pain Syndrome (CRPS)
Status: TERMINATED
Conditions: Complex Regional Pain Syndrome (CRPS)
Interventions: DRUG: Neridronic acid 100 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Investigating the Effect of Idalopirdine on Cardiac Repolarisation in Healthy Men
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Placebo|DRUG: ldalopirdine 120 mg|DRUG: Idalopirdine 360 mg|DRUG: Moxifloxacin 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BAY 1902607: Single Dose Escalation, Safety and Tolerability, Pharmacokinetics, Bioavailability, Food Effect
Status: COMPLETED
Conditions: Clinical Trials, Phase I as Topic
Interventions: DRUG: BAY1902607|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of DWJ1252 in the Treatment of Functional Dyspepsia
Status: COMPLETED
Conditions: Functional Dyspepsia
Interventions: DRUG: DWJ1252|DRUG: Gasmotin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Durvalumab+Olaparib or Durvalumab After Treatment With Durvalumab and Chemotherapy in Patients With Lung Cancer (ORION)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer NSCLC
Interventions: DRUG: Durvalumab|DRUG: Placebo for Olaparib|DRUG: Olaparib|DRUG: Nab-paclitaxel+carboplatin|DRUG: Gemcitabine+carboplatin|DRUG: Pemetrexed+carboplatin|DRUG: Gemcitabine+cisplatin|DRUG: Pemetrexed+cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Versus Corticosteroid Randomized Clinical Trial for Plantar Fasciitis
Status: COMPLETED
Conditions: Fasciitis, Plantar
Interventions: OTHER: Karaoke Exercise|OTHER: Balance walking exercise|OTHER: Forefoot extension exercise|OTHER: Standing one-legged balance exercise:|OTHER: Ankle inversion/eversion exercise|OTHER: Gastrocnemius and soleus stretching|OTHER: Tissue-specific plantar fascia self massage|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Swiss TrAumatic biRth Trial
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Acute Stress Disorder
Interventions: BEHAVIORAL: Brief computerized intervention|BEHAVIORAL: Attention placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiation Dose Escalation in Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: RADIATION: radiochemotherapy 1|RADIATION: radiochemotherapy 2|RADIATION: radiochemotherapy 3|RADIATION: radiochemotherapy 4|RADIATION: radiochemotherapy 5|RADIATION: radiochemotherapy 6
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Pain Control in Rib Fracture With Non-invasive Stabilization (RCT)
Status: UNKNOWN
Conditions: Rib Fractures|Pain|Thorax; Fracture
Interventions: DEVICE: Posthorax Thoraxbelt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Rheumatology Patient Registry and Biorepository
Status: RECRUITING
Conditions: Rheumatic Diseases|Adult Onset Still Disease|Ankylosing Spondylitis|Psoriatic Arthritis|Reactive Arthritis|Antiphospholipid Syndrome|Systemic Lupus Erythematosus|Behcet Disease|Dermatomyositis|Polymyositis|Giant Cell Arteritis|Lyme Disease|Mixed Connective Tissue Disease|Polymyalgia Rheumatica|Rheumatoid Arthritis|Sarcoidosis|Systemic Sclerosis|Scleroderma|Sjogren's Syndrome|Undifferentiated Connective Tissue Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Blood Sample Collection Study for Pharmacogenomic Characterization of Participants That Previously Received Namilumab in M1-1188-002-EM (PRIORA, [NCT01317797]) Study
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single Dose Comparability Study of New and Current Dupilumab Drug Products Subcutaneously Administered in Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Dupilumab (SAR231893)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impacts of Nicotinamide Riboside on Functional Capacity and Muscle Physiology in Older Veterans
Status: RECRUITING
Conditions: Sarcopenia|Nicotinamide Adenine Dinucleotide Concentration|Muscle Quality and NAD+ Content
Interventions: DIETARY_SUPPLEMENT: Nicotinamide Riboside|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Bendamustine, Lenalidomide and Low-dose Dexamethasone, for the Treatment of Patients With Relapsed Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Bendamustine|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Osimertinib With or Without Chemotherapy as 1st Line Treatment in Patients With Mutated Epidermal Growth Factor Receptor Non-Small Cell Lung Cancer (FLAURA2)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Osimertinib|DRUG: Pemetrexed/Carboplatin|DRUG: Pemetrexed/Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: mBrain-21 : a Three-month Study on Context-awareness, Physiological Monitoring, and Machine Learning in Migraine and Cluster Headache
Status: COMPLETED
Conditions: Migraine|Cluster Headache
Interventions: DEVICE: Wearable sensor and smartphone application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pathophysiology of Neuronal Oscillations Within Subthalamo-cortical Loops in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease|Pathophysiology of Neuronal Oscillations Within Subthalamo-cortical Loops
Interventions: OTHER: subthalamo-cortical loops stimulation in a one-sided and bipolar way|OTHER: subthalamo-cortical loops stimulation in a one-sided and bipolar way
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bioequivalence Study of Patches With Different Equilibration Profiles
Status: COMPLETED
Conditions: Female Contraception
Interventions: DRUG: norelgestromin/ethinyl estradiol (NGMN/EE) transdermal contraceptive system.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Faba Bean Fractions as Ingredients in Novel Food Products on Glycemia, Appetite and Metabolic Control
Status: COMPLETED
Conditions: Faba Bean|Post-prandial Blood Glucose|Appetite|Satiety Hormones|Insulin
Interventions: OTHER: Faba bean powder smoothie|OTHER: Faba bean protein concentrate smoothie|OTHER: Faba bean starch smoothie|OTHER: Faba bean protein isolate smoothie|OTHER: Non-pulse smoothie smoothie
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of DC-CIK in Patients With Advanced Non-Small-Cell Lung Cancer With Bone Metastases
Status: UNKNOWN
Conditions: Non-Small-Cell Lung Cancer With Bone Metastases
Interventions: BIOLOGICAL: genetically modified dendritic cells + cytokine-induced killer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endothelial Effects of Basal Insulin: Detemir Versus Glargine
Status: COMPLETED
Conditions: Type 2 Diabetes|Endothelial Dysfunction|Cardiovascular Disease
Interventions: DRUG: Glargine|DRUG: Detemir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 52-Week Multicenter Study Evaluating the Safety and Efficacy of Varenicline for the Maintenance of Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: varenicline (CP-526,555)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Dose-Finding Study Evaluating Safety and Efficacy in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Fluticasone Propionate/Formoterol Fumarate|DRUG: Fluticasone Propionate/Formoterol Fumarate|DRUG: Fluticasone Propionate/Formoterol Fumarate|DRUG: Fluticasone Propionate/Formoterol Fumarate|DRUG: Fluticasone Propionate|DRUG: Formoterol Fumarate|DRUG: Fluticasone Propionate/Salmeterol Xinafoate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: PCOS Treatment Using DLBS3233, Metformin, and Combination of Both
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome (PCOS)|Insulin Resistance
Interventions: DRUG: DLBS3233|DRUG: Metformin XR|DRUG: Placebo metformin|DRUG: Placebo DLBS3233
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of 99mTc-FAPI SPECT/CT and 68Ga-FAPI PET/CT
Status: UNKNOWN
Conditions: 99mTc-FAPI-positive Gastrointestinal Tumor
Interventions: DIAGNOSTIC_TEST: 99mTc-FAPI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nicotinamide in Non-Alcoholic Fatty Liver Disease Patients
Status: COMPLETED
Conditions: Non Alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: Niacinamide Oral Tablet|DRUG: Antidiabetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Analgesic Efficacy and Safety of Subcutaneous Tanezumab in Subjects With Osteoarthritis of the Hip or Knee.
Status: COMPLETED
Conditions: Osteoarthritis, Hip|Osteoarthritis, Knee
Interventions: DRUG: Tanezumab|DRUG: Tanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of HPV-associated Eye Infection and Cytokine Levels in Tears From Patients Diagnosed With Pterygium
Status: COMPLETED
Conditions: Human Papilloma Virus Infection|Pterygium
Interventions: DIAGNOSTIC_TEST: HPV genotyping assay using HPV GenoArray Diagnostic Kits (Hybribio Ltd., Sheung Wan, Hong Kong)|DIAGNOSTIC_TEST: Bio-Plex® 200 system (Bio- Rad, Hercules, CA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I Study to Assess the Pharmacokinetics of Olorofim in Subjects With Renal Impairment
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: Olorofim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Chlorhexidine Gel and Peribioma Periogel Use in Peri-implant Mucositis Sites: a Split-mouth Randomized Clinical Trial.
Status: COMPLETED
Conditions: Peri-implant Mucositis
Interventions: OTHER: Chlorhexidine and Biorepair gel and toothpaste application|OTHER: Standard oral hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Relapse Prediction Model for Resectable Non-Small Cell Patients - a Prospective Clinical Feasibility Trial
Status: RECRUITING
Conditions: Lung Cancer|Relapse/Recurrence
Interventions: DRUG: Cisplatin based chemottherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Evaluation of Laser Therapy Used as an Adjunct to Non-Surgical Treatment of Gum Disease
Status: COMPLETED
Conditions: Periodontitis Chronic Generalized Moderate|Periodontitis Chronic Generalized Severe
Interventions: DEVICE: Laser Therapy|PROCEDURE: Non-surgical Scaling and Root Planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Proton Pump Inhibitor (PPI) Test for the Extraesophageal Manifestation of GERD
Status: UNKNOWN
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Proton pump inhibitor (rabeprazole)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: TAP Block vs LAWI for Analgesia Post-cesarean Section: RCT
Status: COMPLETED
Conditions: Obstetric Pain|Obstetric Anesthesia Problems
Interventions: PROCEDURE: Transversus Abdominis Plane Block|PROCEDURE: Local anesthetic wound infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Indacaterol Plus Tiotropium Versus Tiotropium Alone in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Indacaterol 150 μg|DRUG: Tiotropium 18 μg|DRUG: Placebo to indacaterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Self-management Based Survivorship Intervention for Chinese Cancer Survivors
Status: RECRUITING
Conditions: Physical Symptom Distress|Weight Management|Neoplasms
Interventions: BEHAVIORAL: Cancer survivorship care intervention|BEHAVIORAL: Step-up targeted personalized intervention|BEHAVIORAL: First stage control intervention|BEHAVIORAL: Second stage control intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Superparamagnetic Iron Oxide (SPIO) in Sentinel Lymph Node Detection for Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Sentinel Lymph Node
Interventions: PROCEDURE: sentinel lymph node biopsy procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spleen Transplant in Solid Organ Transplantation
Status: WITHDRAWN
Conditions: Kidney Transplant Rejection|Positive FCXM (T or B Cell Positive)|Positive CDC Cross-Match (B Cell Positive)|Kidney/Pancreas Transplant Rejection
Interventions: PROCEDURE: Spleen Transplantation/Removal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Nivolumab in Combination With Cabozantinib for Metastatic Triple-negative Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Nivolumab|DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inactivated Convalescent Plasma as a Therapeutic Alternative in Patients CoViD-19
Status: UNKNOWN
Conditions: Infections, Coronavirus
Interventions: DRUG: Inactivated convalescent plasma|DRUG: Support treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Total Lifestyle Reconstruction for Body Weight Control and Maintenance
Status: ACTIVE_NOT_RECRUITING
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Designed on-line course A with 3-month consultation with the dietitian|BEHAVIORAL: Designed on-line course B with 3-month consultation with the dietitian|BEHAVIORAL: Designed on-line course B with 3-month consultation with the dietitians + 3-month daily dietary assessment by the dietitians|BEHAVIORAL: Designed on-line course B with 6-month consultation with the dietitians + 6-month daily dietary assessment by the dietitians
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Objective Particle Swarm Optimization Postural Instability Gait Disorder
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: OTHER: Deep Brain Stimulation, STN|OTHER: GP Deep Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Different Application Strategies When Using Ambar Universal in Class V Cavities
Status: COMPLETED
Conditions: Dental Restoration Failure of Marginal Integrity
Interventions: OTHER: Self-Etching Application Strategy|OTHER: Enamel Etching Application Strategy|OTHER: Self Etching with Extended time Application Strategy|OTHER: Self Etching with Extended layers number Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NP-G2-044 as Monotherapy and Combination Therapy in Patients With Advanced or Metastatic Solid Tumor Malignancies
Status: RECRUITING
Conditions: Advanced or Metastatic Solid Tumor Malignancies
Interventions: DRUG: NP-G2-044 Monotherapy|DRUG: Anti-PD-1 Therapy|DRUG: NP-G2-044 Combination therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: N-Acetylcysteine vs Placebo as Adjunctive Treatment in Pediatric Leukemia
Status: TERMINATED
Conditions: Lymphoblastic Leukemia, Acute, Childhood
Interventions: DRUG: N-Acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of Oral Supplementation of Arginine, Zinc and Vitamin C on Collagen Synthesis in Inguinal Hernia Patients
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: DIETARY_SUPPLEMENT: Intervention|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE