pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Ruxolitinib Phosphate, Paclitaxel, and Carboplatin in Treating Patients With Stage III-IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: UNKNOWN
Conditions: Fallopian Tube Clear Cell Adenocarcinoma|Fallopian Tube Endometrioid Adenocarcinoma|Fallopian Tube High Grade Serous Adenocarcinoma|FIGO Stage III Ovarian Cancer|FIGO Stage IIIA Ovarian Cancer|FIGO Stage IIIA1 Ovarian Cancer|FIGO Stage IIIA2 Ovarian Cancer|FIGO Stage IIIB Ovarian Cancer|FIGO Stage IIIC Ovarian Cancer|FIGO Stage IVA Ovarian Cancer|FIGO Stage IVB Ovarian Cancer|Ovarian Clear Cell Adenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian High Grade Serous Adenocarcinoma|Primary Peritoneal Endometrioid Adenocarcinoma|Primary Peritoneal High Grade Serous Adenocarcinoma|Stage III Fallopian Tube Cancer AJCC v7|Stage III Primary Peritoneal Cancer AJCC v7|Stage IIIA Fallopian Tube Cancer AJCC v7|Stage IIIA Primary Peritoneal Cancer AJCC v7|Stage IIIB Fallopian Tube Cancer AJCC v7|Stage IIIB Primary Peritoneal Cancer AJCC v7|Stage IIIC Fallopian Tube Cancer AJCC v7|Stage IIIC Primary Peritoneal Cancer AJCC v7|Stage IV Fallopian Tube Cancer AJCC v6 and v7|Stage IV Primary Peritoneal Cancer AJCC v7
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Ruxolitinib Phosphate|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Online Pilates and Face-To-Face Pilates on Healthy Individuals
Status: COMPLETED
Conditions: Healthy Lifestyle|Health Behavior
Interventions: OTHER: Online and Face-to-face Pilates trainings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modafinil in Treating Fatigue and Behavioral Change in Patients With Primary Brain Cancer
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Cognitive/Functional Effects|Fatigue
Interventions: DRUG: modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Antibiotic Treatment for Skin Abscess in Patients at Risk for Methicillin-Resistant Staphylococcus Aureus (MRSA) Infection
Status: COMPLETED
Conditions: Abscess
Interventions: DRUG: Septra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Silodosin on Feasibility of Ureteral Access Sheath Insertion
Status: RECRUITING
Conditions: Renal Stone
Interventions: PROCEDURE: Ureteral access sheath placement during flexible ureteroscope for renal stones
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of a Morcellator in Operative Hysteroscopy for Benign Intracavitary Lesions: a Feasibility Study
Status: COMPLETED
Conditions: Endometrial Polyp Benign|Retained Products of Conception|Myoma;Uterus
Interventions: PROCEDURE: Hysteroscopic morcellation 19 Fr. intrauterine BIGATTI Shaver for uterine intracavitary lesions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Plasma Exchange as an Adjunctive Strategy to Treat Coagulopathy and Inflammation in Severe Covid-19
Status: UNKNOWN
Conditions: Severe Covid-19
Interventions: DEVICE: therapeutic plasmaexchnage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Sensory Stimulation on Attenuating Pain and Stress Among Patients With Disorders of Consciousness
Status: COMPLETED
Conditions: Disorder of Consciousness
Interventions: BEHAVIORAL: Auditory stimulation|BEHAVIORAL: Auditory and tactile stimulations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Wingate-type Exercise Test to Evaluate the Effect of High Velocity Therapy on Recovery Sensation and Blood Lactate Decline
Status: ACTIVE_NOT_RECRUITING
Conditions: Dyspnea|Lactic Acidosis|Muscle|Breathlessness|Exercise|Recovery
Interventions: DEVICE: high velocity therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of White Rice, Brown Rice, and Black Rice on Postprandial Glucose and Lipid Profiles in Healthy Korean Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: White rice diet|DIETARY_SUPPLEMENT: Brown rice diet|DIETARY_SUPPLEMENT: Black rice diet|DIETARY_SUPPLEMENT: Bread|OTHER: Glucose solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of 3-year Lifestyle Intervention on Postprandial Glucose Metabolism: the SLIM Study
Status: COMPLETED
Conditions: Impaired Glucose Tolerance|Type 2 Diabetes
Interventions: BEHAVIORAL: diet- and exercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: OZURDEX in Age Related Macular Degeneration as Adjunct to Ranibizumab
Status: COMPLETED
Conditions: Wet Macular Degeneration
Interventions: DRUG: Ranibizumab|DRUG: OZURDEX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Ultrasound Determines Disease Activity in Crohn's Disease And Ulcerative Colitis
Status: UNKNOWN
Conditions: Crohn Disease|Ulcerative Colitis
Interventions: PROCEDURE: Endoscopic ultrasound catheter (UM-2R/3R, Olympus)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dopamine and Norepinephrine Infusion With Restricted Hydration
Status: COMPLETED
Conditions: Renal Function Test, Urine Output, Lactate Level
Interventions: DRUG: Norepinephrine, dopamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Does Atorvastatin Prevent Post Operative Atrial Fibrillation After Pulmonary Resection: A Randomized Clinical Study
Status: COMPLETED
Conditions: Arrhythmia
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Immediate Effects of Intermittent Theta Burst Stimulation on Intracortical Excitability of the Primary Motor Cortex in Patients With Chronic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Intermittent theta burst stimulation (iTBS)|DEVICE: Sham intermittent theta burst stimulation (iTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Efficacy and Safety of CT-P43 to Stelara in Patients With Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: CT-P43|BIOLOGICAL: Stelara
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radical Cure (RC) With Tafenoquine or Primaquine After Semi-quantitative G6PD Testing: A Feasibility Study in Peru
Status: RECRUITING
Conditions: Malaria, Vivax
Interventions: OTHER: Training on revised algorithm|OTHER: Enhancing Pharmacovigilance|OTHER: Supervision of malaria services in selected facilities.|DIAGNOSTIC_TEST: G6PD testing|DRUG: Tafenoquine|DRUG: Primaquine|OTHER: Follow Up Visit at Day 3 [+2 days] after treatment start
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CSD210904: Study to Assess Actual Use of a Heated Tobacco Product With Four Non-Combusted Cigarette Variants in Current Adult Smokers
Status: COMPLETED
Conditions: Smoking|Tobacco Use|Tobacco Smoking
Interventions: OTHER: 40007388|OTHER: 40007385|OTHER: 40007387|OTHER: 40007386
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Serratus Anterior Plane Block Versus Thoracic Paravertebral Block.
Status: UNKNOWN
Conditions: Rib Fractures|Analgesia
Interventions: PROCEDURE: Serratus anterior plane block|PROCEDURE: Thoracic Paravertebral block|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of BART Coupled With EEG in the Early Diagnosis of Behavioral Disorders in Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: BART-EEG at V1 + V2|BEHAVIORAL: BART-EEG at V1 only
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trial Comparing Pain in Single-incision Laparoscopic Cholecystectomy Versus Conventional Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Cholelithiasis|Choledocholithiasis|Cholecystolithiasis|Pancreatitis|Cholangitis
Interventions: PROCEDURE: SILC|PROCEDURE: LC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FOLFIRINOX + NIS793 in Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreas Cancer|Metastatic Pancreatic Cancer|Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: FOLFIRINOX|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: Irinotecan|DRUG: 5-Fluorouracil (5-FU)|DRUG: NIS793|RADIATION: Chemoradiation|DRUG: Capecitabine|RADIATION: Radiation Therapy|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Facet Versus Trigger Point Injections for Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: PROCEDURE: Betamethasone|PROCEDURE: Dexamethasone|PROCEDURE: Intramuscular Lidocaine|BEHAVIORAL: Home Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imaging Study of the Lungs During an Allergic Asthma Attack
Status: COMPLETED
Conditions: Asthma|Atopy
Interventions: BIOLOGICAL: Standardized Cat Allergen Extract and Standardized Dust Mite Allergen|RADIATION: Computed Tomography imaging, functional Positron Emission Tomography imaging|DRUG: Nebulized methacholine inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Surufatinib Combined With Toripalimab in Recurrent or Metastatic Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Surufatinib(HMPL-012)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Effectiveness and Safety of Levofloxacin to That of Ciprofloxacin in Treating Complicated Urinary Tract Infection and Acute Pyelonephritis.
Status: COMPLETED
Conditions: Urinary Tract Infections|Pyelonephritis
Interventions: DRUG: levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Guided Self-Help for Parents of Children With Externalizing Problem Behavior
Status: UNKNOWN
Conditions: Oppositional Defiant Disorder|Attention Deficit Hyperactivity Disorders|Attention Deficit and Disruptive Behavior Disorders
Interventions: BEHAVIORAL: Cognitive-Behavioral Self-help Workbook + Counseling Telephone Calls|BEHAVIORAL: Non-Directive Self-Help Workbook + Counseling Telephone Calls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Use of Noninvasive Brain Stimulation in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sunitinib, Irinotecan, Fluorouracil, and Leucovorin In Treating Patients With Advanced Stomach Cancer or Gastroesophageal Cancer
Status: TERMINATED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium|DRUG: sunitinib malate|OTHER: flow cytometry|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Economic Comparison of Robot Assisted Versus Manual Knee Replacement
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Arthroplasty
Interventions: PROCEDURE: Total Knee Arthroplasty|PROCEDURE: MAKO® Robot Assisted Medial Knee Arthroplasty|DEVICE: RESTORIS Multicompartmental Knee System|DEVICE: Depuy Knee Replacement System|DEVICE: Stryker® Knee Replacement System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adolescents With Substance Use Disorders Transitioníng From Residential Treatment to the Community
Status: COMPLETED
Conditions: Substance Use|Adolescent Behavior
Interventions: BEHAVIORAL: Parenting Wisely+|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Delapril and Manidipine for Nephroprotection in Diabetes (DEMAND)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Delapril, Delapril-Manidipine Fixed combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Oxygen Control and Weaning by O2matic to Patients Admitted With an Exacerbation of COPD
Status: COMPLETED
Conditions: COPD Exacerbation|Hypoxia|Hypoxemia|Hyperoxia|Respiratory Failure|Respiratory Insufficiency|Copd Exacerbation Acute
Interventions: DEVICE: O2matic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamics of Risk Perception and Risk Behavior in Alcohol Use Disorder and Schizophrenia
Status: UNKNOWN
Conditions: Alcohol Use Disorder (AUD)|Schizophrenia and Related Disorders
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for reducing risk behaviors|BEHAVIORAL: Cognitive Behavioral Therapy for increasing non-risk behaviors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 1 Clinical Study to Investigate the Pharmacokinetics and Safety/Tolerability of SA001 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SA001 60mg or Placebo|DRUG: SA001 120mg or Placebo|DRUG: SA001 180mg or Placebo|DRUG: SA001 240mg or Placebo|DRUG: SA001 300mg or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: ABT-348 as Monotherapy or Combination With Carboplatin or Docetaxel to Treat Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: ABT-348|DRUG: ABT-348 and carboplatin|DRUG: ABT-348 and docetaxel|DRUG: ABT-348|DRUG: ABT-348
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Atezolizumab Compared With a Single-Agent Chemotherapy in Treatment Naïve Participants With Locally Advanced or Recurrent or Metastatic Non-Small Cell Lung Cancer Who Are Deemed Unsuitable For Platinum-Doublet Chemotherapy
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Atezolizumab (MPDL3280A), an engineered anti-PD-L1 antibody|DRUG: Vinorelbine|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mycophenolate Mofetil in Systemic Sclerosis
Status: COMPLETED
Conditions: Diffuse Cutaneous Systemic Sclerosis
Interventions: DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Evaluate the Effectiveness of Ultrasound Guided Looped Thread Carpal Tunnel Release
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Thread carpal tunnel release
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Lumasiran in Healthy Adults and Patients With Primary Hyperoxaluria Type 1
Status: COMPLETED
Conditions: Primary Hyperoxaluria Type 1 (PH1)
Interventions: DRUG: Lumasiran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Muscular Rehabilitation by Eccentric Exercise After Severe COVID-19 Infection
Status: TERMINATED
Conditions: Covid19|Sarcopenia|Muscle Weakness
Interventions: OTHER: Rehabilitation by Eccentric exercises|OTHER: Rehabilitation by Concentric exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hematological Response in Patients With Paroxysmal Nocturnal Hemoglobinuria Treated With Anti-C5 Antibody: an External Control Arm Study for Iptacopan Use in Anti-C5 naïve Patients
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: OTHER: Anti-C5 antibody treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cisplatin and Paclitaxel in Treating Patients With Stage IIB, Stage IIC, Stage III, or Stage IV Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cavity Cancer
Status: COMPLETED
Conditions: Chemotherapeutic Agent Toxicity|Endometrial Adenocarcinoma|Fallopian Tube Carcinoma|Gastrointestinal Complication|Malignant Ovarian Mixed Epithelial Tumor|Neurotoxicity Syndrome|Ovarian Brenner Tumor|Ovarian Clear Cell Cystadenocarcinoma|Ovarian Mucinous Cystadenocarcinoma|Ovarian Serous Cystadenocarcinoma|Primary Peritoneal Carcinoma|Stage II Ovarian Cancer|Stage III Ovarian Cancer|Stage IV Ovarian Cancer|Undifferentiated Ovarian Carcinoma
Interventions: DRUG: Paclitaxel|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gefitinib and Everolimus in Treating Patients With Stage IIIB or Stage IV or Recurrent Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: everolimus|DRUG: gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Oriented Recovery Enhancement (MORE) in Heroin Addiction
Status: RECRUITING
Conditions: Opiate Use Disorder
Interventions: BEHAVIORAL: Behavioral group therapy #1|BEHAVIORAL: Behavioral group therapy #2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Need for Subcutaneous Wound Drains in Ileostomy Reversal
Status: COMPLETED
Conditions: Presence of Ileostomy
Interventions: PROCEDURE: insertion of subcutaneous wound drain|PROCEDURE: no insertion of subcutaneous wound drain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Salivary IgA and Cytokines Response to Dietary Supplementation of Lactobacillus Reuteri
Status: COMPLETED
Conditions: Dental Caries|Periodontitis
Interventions: DIETARY_SUPPLEMENT: L. reuteri DSM 17938/ATCC PTA|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Prospective Randomized Study for Comparison of Y-Composite Grafts
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: saphenous vein composite grafting|PROCEDURE: right internal thoracic artery composite grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Immunotherapy in Combination With Ublituximab and Umbralisib in Patients With Relapsed-refractory CLL or Richter's Transformation
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Richter Syndrome
Interventions: DRUG: Umbralisib|BIOLOGICAL: ublituximab|BIOLOGICAL: TG-1501
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abraxane Plus Carboplatin for Recurrent Platinum-Sensitive Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: DRUG: Abraxane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Otelixizumab for Adults With Newly Diagnosed Type 1 Diabetes Mellitus (Autoimmune): DEFEND-1
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: BIOLOGICAL: otelixizumab infusion plus physician determined standard of care|BIOLOGICAL: placebo infusion plus physician determined standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Clinical Evaluation of Periodontal Response to Different Prosthetic Margin Design
Status: COMPLETED
Conditions: Gingival Recession|Gingival Disease|Gingival Bleeding
Interventions: PROCEDURE: Horizontal Tooth preparation|PROCEDURE: Vertical Tooth preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Levels of Visfatin/NAMPT in Human Milk
Status: NOT_YET_RECRUITING
Conditions: Measure Visfatin Levels in Maternal Milk Samples Collected in Three Different Moments After Birth 48 Hours 7 Days and 30 Days|Measure Visfatin Levels in Maternal Plasma/Serum Collected After 1-2 Days Post-partum|Correlate the Values of Visfatin to Different Demographic and Clinical Characteristics of the Lactating Mothers|Correlate the Values of Visfatin to Different Biological/Clinical Features of the Newborns
Interventions: OTHER: observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neo-Sequence 2：NCT Plus Anti-angiogenesis Therapy and Immunotherapy for LADGC
Status: RECRUITING
Conditions: Gastric Cancer|Diffuse Type Carcinoma
Interventions: DRUG: Albumin paclitaxel+SOX+BEV+ PD-1 monoclonal antibody therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic Polymorphisms of Interleukin-1B and TNF-A and HBV-Related Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatitis B|Hepatocellular Carcinoma|Chronic Liver Disease
Interventions: GENETIC: Polymorphism of IL-1 beta and TNF-alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Thoracic Paravertebral Block , Pectoral Nerve Block to Serratus Anterior Plane Block in Breast Surgery, A Randomized Controlled Study
Status: COMPLETED
Conditions: Comparison of Thoracic Paravertebral Block to Serratus Anterior Plane Block in Breast Surgery
Interventions: PROCEDURE: Thoracic paravertebral block(TPVB) group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Psoriasis Plaque Test Comparing Eight Different Formulations of Vitamin D Analogues for the Treatment of Psoriasis
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Six different calcipotriol ointment formulations, and two currently marketed topical vitamin D analogues
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Digital Data Linkage and Scheduling to Track Pregnancy With or Without Community Data Use to Increase Antenatal Clinic Uptake in Western Kenya.
Status: NOT_YET_RECRUITING
Conditions: Health Systems|Electronic Community Health Information Systems|Antenatal Clinic Uptake|Pregnancy
Interventions: OTHER: The combined "C-it DU-it" intervention: community data use for ANC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dose Optimization Trial of CD19 Redirected Autologous T Cells
Status: COMPLETED
Conditions: Adult Patients Who Have Relapsed or Refractory CLL (3rd Line) or SLL
Interventions: BIOLOGICAL: CART-19
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Bupe by the Book": A Tele-Buprenorphine Clinical Trial in Public Libraries With Unstably Housed Persons With Opioid Use Disorder
Status: RECRUITING
Conditions: Telehealth at the Library|Control Group
Interventions: BEHAVIORAL: Buprenorphine uptake/retention via Telehealth|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-surgical Mechanical Therapy of Peri-implantitis With or Without Adjunctive Diode Laser Application
Status: COMPLETED
Conditions: Peri-Implantitis
Interventions: DEVICE: Diode laser application|DEVICE: Sham Diode laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetic Profile of Salbutamol Delivered by Unit Dose Dry Powder Inhaler (UD-DPI) Compared to the Diskus and Metered Dose Inhaler (MDI) in Healthy Volunteers.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Salbutamol Sulphate 150mcg UD-DPI Blister(1.6% blend)|DRUG: Salbutamol Sulphate 200mcg UD-DPI Blister(1.6% blend)|DRUG: Salbutamol Sulphate 250mcg UD-DPI Blister(1.6% blend)|DRUG: Salbutamol Sulphate 200mcg UD-DPI Blister(1% blend)|DRUG: Salbutamol Diskus 200mcg Blister|DRUG: Salbutamol MDI 100mcg|DRUG: Salbutamol Sulphate UD-DPI Blister (selected from Part A)|DRUG: Salbutamol Sulphate 250mcg UD-DPI Blister (selected from Part A)|DRUG: Salbutamol Diskus 200mcg Blister without activated charcoal|DRUG: Salbutamol Diskus 200mcg Blister with activated charcoal|DRUG: Salbutamol MDI 100mcg without activated charcoal|DRUG: Salbutamol MDI 100mcg with activated charcoal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiparametric Echocardiography and Cardiac Biomarkers in Pediatric Inflammatory Heart Diseases
Status: NOT_YET_RECRUITING
Conditions: Myocarditis|Pediatric Inflammatory Multisystem Syndrome|Kawasaki Disease
Interventions: OTHER: study of biological samples and echocardiographic data and link with need of hemodynamic support
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Molecular Point-of-care Xpert® Xpress SARS-CoV-2 Detection Implementation in Resource-limited Settings
Status: UNKNOWN
Conditions: COVID-19
Interventions: DEVICE: Gene Expert molecular Point-of-Care (POC) (Xpert® Xpress SARS-CoV-2/Flu/RSV test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of SH T00660AA in Treatment of Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Visanne (SH T00660AA , BAY86-5258)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Helicobacter Eradication Aspirin Trial
Status: COMPLETED
Conditions: Gastrointestinal Ulcer Haemorrhage|Bacterial Infection Due to Helicobacter Pylori (H. Pylori)
Interventions: DRUG: Lansoprazole 30mg, Clarithromycin 500mg, Metronidazole 400mg|DRUG: Placebo lansoprazole 30mg, clarithromycin 500mg, metronidazole 400mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Ledipasvir/Sofosbuvir in Adults With Chronic HCV Infection
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: LDV/SOF|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Prucalopride for the Treatment of Chronic Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Prucalopride|OTHER: Placebo|DRUG: Prucalopride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of ALBIS on Gastroduodenal Mucosal Injury in Patients Receiving Dual Antiplatelet Therapy After Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Gastritis|Gastroduodenal Ulcer
Interventions: DRUG: ALBIS|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Hematopoietic Stem Cell Transplantation for Allogeneic Organ Transplant Tolerance
Status: COMPLETED
Conditions: Complication of Transplanted Organ, Nos
Interventions: DRUG: Autologous Hematopoietic Stem Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarker Analysis in High PD-L1 Expressing NSCLC Patients Treated With PD-1/PD-L1 Based Therapy With or Without the Addition of Platinum Based Chemotherapy
Status: TERMINATED
Conditions: NSCLC Stage IV|NSCLC, Stage IIIC
Interventions: DIAGNOSTIC_TEST: Primary Immune Response (PIR) test by Biodesix, Inc.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Intervention to Reduce Prolonged Sitting in Police Staff
Status: COMPLETED
Conditions: Sedentary Behavior|Metabolic Syndrome|Affect|Stress, Physiological|Stress, Psychological|Musculoskeletal Pain
Interventions: BEHAVIORAL: Breaks
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study Evaluating Toxicity & Efficacy of Lenalidomide(Revlimid®)in Chemotherapy-Naïve AIPC Patients
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Revlimid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamic Evaluation of Ankle Joint and Muscle Mechanics in Children With Spastic Equinus Deformity Due to Cerebral Palsy
Status: TERMINATED
Conditions: Equinus Deformity
Interventions: RADIATION: MRI scanner|OTHER: Gait analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability and Pharmacokinetics of NYX-783 and Oxycodone DDI Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid Use Disorder
Interventions: DRUG: NYX-783|DRUG: Placebo|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Video Laryngoscopy (Video Macintosh-blade) and Direct Laryngoscopy (EMMA-Study)
Status: COMPLETED
Conditions: Airway Morbidity
Interventions: DEVICE: the McGrath MAC|DEVICE: the Macintosh Laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Testosterone on Prostate Tissue (ACYP-1)
Status: COMPLETED
Conditions: Hypogonadism|Contraception
Interventions: DRUG: Testosterone gel|DRUG: Acyline|DRUG: Placebo acyline|DRUG: Placebo Testosterone gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Interest of the Immunoscore® as a Post-operative Complementary Tool for the Detection of the Risk of Recurrence in Patients With Nonmetastatic Colorectal Cancer
Status: RECRUITING
Conditions: Non Metastatic Colorectal Cancer
Interventions: DIAGNOSTIC_TEST: IMMUNOSCORE®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Predictive Value of FMISO-PET, FDG-PET-CT, DWI-MRI and DCE-MRI Scans for Patients With Anal Cancer Receiving Radiotherapy +/- Chemotherapy
Status: UNKNOWN
Conditions: Anal Cancer
Interventions: OTHER: FMISO-PET, FDG-PET-CT and Magnetic Resonance Imaging (MRI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial of BP1001 (Liposomal Grb2 Antisense Oligonucleotide) in Combination With Dasatinib in Patients With Ph + CML Who Have Failed TKI, Ph+ AML, Ph+ MDS
Status: WITHDRAWN
Conditions: Chronic Myelogenous Leukemia, Ph1-Positive|Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: BP1001 (varying dose)|DRUG: BP1001 (fixed dose)|DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stromal Cell Derivatives in the Treatment of Chronic Diabetic Foot Ulcers Type 1 and 2
Status: UNKNOWN
Conditions: Foot Ulcer, Diabetic
Interventions: OTHER: dac-MSCs|OTHER: MSCs|DRUG: Fitostimoline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regorafenib Plus 5-Fluorouracil/Leucovorin Beyond Progression in mCRC
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: Regorafenib|DRUG: 5-FU|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardio-fistular Recirculation in Patients With Chronic Heart Failure and Preserved Left Ventricle Ejection Fraction
Status: COMPLETED
Conditions: Chronic Kidney Disease 5D|Heart Failure|Heart Failure NYHA Class I|Heart Failure NYHA Class II
Interventions: PROCEDURE: Hemodialysis session
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Holmium Versus Bipolar en Bloc Transurethral Resection of Urothelium Tumor of the Urinary Bladder
Status: UNKNOWN
Conditions: Urinary Bladder Neoplasm
Interventions: PROCEDURE: Holmium versus Bipolar en bloc transurethral resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kinetics and Impact on Survival of MRD in AML Patients Receiving Azacitidine and Venetoclax
Status: NOT_YET_RECRUITING
Conditions: AML, Adult|Minimal Residual Disease
Interventions: DIAGNOSTIC_TEST: MRD assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cost-Effectiveness of a Specialized Ultrasound Instrument to Diagnose Carotid Stenosis as a Way to Reduce the Risk of Stroke
Status: COMPLETED
Conditions: Carotid Stenosis|Cerebrovascular Accident
Interventions: DEVICE: Specialized Doppler Ultrasound Instrument
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pain Assessment During Less-Invasive-Surfactant-Administration
Status: COMPLETED
Conditions: Infant, Premature, Diseases|Respiratory Distress Syndrome|Surfactant Deficiency Syndrome Neonatal|Pain|Stress
Interventions: OTHER: Skin Conductance (SC) Measurement|OTHER: Video Recording
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Distress Screening + Consultation With Enhanced Usual Care for Caregivers of Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer Caregivers
Interventions: BEHAVIORAL: Baseline questionnaire|BEHAVIORAL: NCCN Problem List|BEHAVIORAL: FACT-GP|BEHAVIORAL: HADS|BEHAVIORAL: CSS-CG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multicenter Randomized Parallel Group Phase III Study Comparing the Bowel Cleansing Efficacy, Safety and Tolerability of NER1006 Versus Trisulfate Solution Using 2-Day Split-Dosing Regimen in Adults
Status: COMPLETED
Conditions: Colon Cancer|Colorectal Carcinoma|Colon Cleansing
Interventions: DRUG: NER1006|DRUG: Trisulfate solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Georgia: Technology and WIC - A Comprehensive Approach to Public Health
Status: COMPLETED
Conditions: Telehealth|Nutrition Education|Breast Feeding|Dietary Intake|WIC
Interventions: BEHAVIORAL: Telehealth solution: video conferencing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Tasigna®/Nilotinib (AMN107) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas
Status: COMPLETED
Conditions: Neurofibromatosis|NF1|Neurofibromas
Interventions: DRUG: Tasigna
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of High Dose Biotin in Patients With Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Biotin|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II 225Ac-J591 Plus 177Lu-PSMA-I&T for Progressive Metastatic Castration Resistant Prostate Cancer
Status: SUSPENDED
Conditions: Prostate Cancer
Interventions: DRUG: 225Ac-J591|DRUG: 177Lu-PSMA-I&T|DRUG: 68Ga-PSMA-11
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expansion of Virus-Specific Lymphocytes for Cell Therapy
Status: RECRUITING
Conditions: CMV Viremia|CMV
Interventions: COMBINATION_PRODUCT: Lymphocyte infusion (ImmuneCellVir-I)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palatability (Energy I Pilot)
Status: COMPLETED
Conditions: Energy Density
Interventions: OTHER: Breakfast (1-2 hours, in the morning)|OTHER: Lunch (1-2 Hours, at midday)|OTHER: Dinner (1-2 hours, in the afternoon)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Interventional Bronchoscopy Under Noninvasive Ventilation
Status: UNKNOWN
Conditions: Noninvasive Positive Pressure Ventilation;|Sedation;|Bronchoscopy；|Interventional；|Central Airway Stenosis
Interventions: PROCEDURE: invasive ventilation|PROCEDURE: interventional bronchoscopy|DEVICE: noninvasive ventilation|DRUG: sedation(dezocine and midazolam)|DRUG: general anesthesia(midazolam, fentanyl，rocuronium，propofol and Remifentanil）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Test 2 Doses of GSK Biologicals' Oral Live Attenuated Human Rotavirus (HRV) Vaccine in Healthy Infants in Co-administration With Specific Childhood Vaccines
Status: COMPLETED
Conditions: Infections, Rotavirus
Interventions: BIOLOGICAL: Rotavirus (vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ramelteon 8 mg Tablets Specified Drug-use Survey: <Long-term Survey on Insomnia Accompanied by Difficulty Falling Asleep> - Transitional Survey From the Preceding Drug-use Survey -
Status: COMPLETED
Conditions: Insomnia
Interventions: DRUG: Ramelteon
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Conventional Fluid Management vs Plethysmographic Variability Index -Based Goal Directed Fluid Management
Status: COMPLETED
Conditions: Fluid Management During Elective Spine Surgeries
Interventions: PROCEDURE: General anaesthesia|DRUG: Conventional fluid managment|DRUG: PVI dependant goal directed fluid therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Multi-center, Open-label Study of Oral ENMD-2076 for the Treatment of Patients With Advanced Fibrolamellar Carcinoma
Status: COMPLETED
Conditions: Advanced Adult Hepatocellular Carcinoma|Advanced Fibrolamellar Carcinoma
Interventions: DRUG: ENMD-2076
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of 5 Days of M02-472 Clarithromycin Extended-Release Tablets to 7 Days of Clarithromycin Immediate-Release Tablets for the Treatment of Exacerbation of Chronic Bronchitis
Status: COMPLETED
Conditions: Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB).
Interventions: DRUG: clarithromycin extended-release tablets|DRUG: clarithromycin immediate-release tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pan-intestinal Capsule Endoscopy Versus Colonoscopy in Iron Deficiency Anemia or Overt GI Bleeding
Status: COMPLETED
Conditions: Iron Deficiency Anemia|GastroIntestinal Bleeding
Interventions: DIAGNOSTIC_TEST: Pan-intestinal capsule endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: To Demonstrate the Relative Bioavailability, Parallel Study Of Leflunomide 20 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Psoriatic Arthritis
Interventions: DRUG: Leflunomide 20 mg Tablets (Geneva Pharmaceutical)|DRUG: Arava 20 mg Tablets (Aventis Pharmaceutical, Inc.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of BXCL501 In Agitation Associated With Delirium in ICU Patients
Status: WITHDRAWN
Conditions: Agitation|Delirium
Interventions: DRUG: BXCL501|DRUG: Placebo film
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Single-arm, Multicenter Clinical Trial of Safety and Effectiveness of EUS-LA for Liver Cancer
Status: NOT_YET_RECRUITING
Conditions: Liver Cancer
Interventions: DEVICE: EUS-LA by LaserPro Diode Laser System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Pharmacokinetics, Safety and Tolerability of the Pediatric and Adult Branaplam Formulation in Healthy Adults and the Effect of Food on the Latter.
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: LMI070|DRUG: LMI070|DRUG: LMI070|DRUG: LMI070
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of GFH018 in Combination With Toripalimab in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumor
Interventions: DRUG: GFH018|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of a 13-valent Pneumococcal Polysaccharide Conjugate Vaccine
Status: RECRUITING
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: Investigational 13-valent Pneumococcal Polysaccharide Conjugate Vaccine|BIOLOGICAL: Control 13-valent Pneumococcal Polysaccharide Conjugate Vaccine ( WALVAX PCV13)|BIOLOGICAL: Control 13-valent Pneumococcal Polysaccharide Conjugate Vaccine ( Pfizer PCV13)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Laser-assisted Hyaluronic Acid Delivery by Fractional CO2 Laser in Facial Skin Remodeling
Status: COMPLETED
Conditions: Facial Skin Remodeling
Interventions: OTHER: Laser-assisted hyaluronic acid delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Procedure for Identifying Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: DRUG: isosulfan blue|PROCEDURE: lymphangiography|PROCEDURE: sentinel lymph node biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Implementation of First-trimester Screening and preventiOn of pREeClAmpSia Trial (FORECAST)
Status: COMPLETED
Conditions: Pre-Eclampsia
Interventions: OTHER: Low-dose aspirin in women with high risk of preeclampsia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION