pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Gaze Contingent Feedback in Social Anxiety Disorder
Status: COMPLETED
Conditions: Phobia, Social
Interventions: BEHAVIORAL: attention modification|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Massage Therapy on Severity of Restless Legs Syndrome and Quality of Life in Hemodialysis Patients
Status: COMPLETED
Conditions: Hemodialysis
Interventions: BEHAVIORAL: massage therapy with lavender oil|BEHAVIORAL: massage therapy with baby oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies
Status: RECRUITING
Conditions: Hematologic Malignancy|AML|ALL|BPDCN|MDS|Lymphoblastic Lymphoma|Lymphoma, B-Cell|Lymphoma, T-Cell|Hodgkin Lymphoma|Mixed Phenotype Acute Leukemia|Acute Undifferentiated Leukemia
Interventions: DRUG: Tagraxofusp|DRUG: Fludarabine|DRUG: Cytarabine|DRUG: Dexamethasone|DRUG: Vincristine|DRUG: Azacitidine|DRUG: Methotrexate|DRUG: Cytarabine IT|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Spartalizumab, mDCF and Radiotherapy in Patients With Metastatic Squamous Cell Anal Carcinoma
Status: RECRUITING
Conditions: Squamous Cell Anal Carcinoma|Metastatic Squamous Cell Carcinoma
Interventions: BIOLOGICAL: Sample collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefit of Pharyngeal and Oesophageal pH-impedance of Patients With High Suspicion of Laryngopharyngeal Reflux
Status: COMPLETED
Conditions: Laryngopharyngeal Reflux|Oesophageal pH-impedance
Interventions: DRUG: esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-ascending Dose Study With a Food-Effect Cohort to Evaluate AMG 581
Status: COMPLETED
Conditions: Schizophrenia or Schizoaffective Disorder
Interventions: DRUG: AMG 581|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Support for PARents of Children Living With ADHD - a Research Trial
Status: UNKNOWN
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: BEHAVIORAL: Parents InC|BEHAVIORAL: Incredible Years
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: COntinuous vs BOlus Nasogastric Feeding in Mechanically Ventilated Pediatric Patients 2
Status: COMPLETED
Conditions: Dietary Modification
Interventions: OTHER: Continuous Gastric Feeding|OTHER: Bolus Gastric Feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enteral Nutrition Tolerance and the Gut Microbiome Study
Status: RECRUITING
Conditions: Enteral Feeding Intolerance
Interventions: DIETARY_SUPPLEMENT: Polymeric Tube Feeds|DIETARY_SUPPLEMENT: Blenderized Tube Feeds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TOKA: Custom Made Devices for High Tibial Osteotomy (HTO) - Clinical Investigation
Status: UNKNOWN
Conditions: Unicompartmental Medial Knee Osteoarthritis
Interventions: DEVICE: High Tibial Osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab With Chemotherapy and MK-4830 for Treating Participants With Ovarian Cancer (MK-4830-002)
Status: ACTIVE_NOT_RECRUITING
Conditions: High-grade Serous Ovarian Carcinoma|Ovarian Carcinoma
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Paclitaxel|DRUG: Carboplatin|BIOLOGICAL: Avastin|BIOLOGICAL: MK-4830|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Cord Blood Stem Cell Infusion for the Treatment of Cerebral Palsy in Children
Status: WITHDRAWN
Conditions: Cerebral Palsy
Interventions: BIOLOGICAL: Cord Blood Infusion|BIOLOGICAL: Intravenous Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RN624 In Adult Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Naproxen|DRUG: Placebo|DRUG: PF-04383119 (RN624)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Stimulation of the Prefrontal Cortex on Language Production in Aphasic Patients
Status: COMPLETED
Conditions: Aphasia
Interventions: DEVICE: transcranial direct current stimulation|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Tolerability of SYNB8802 in Healthy Adult Volunteers and Adult Subjects With Enteric Hyperoxaluria
Status: COMPLETED
Conditions: Healthy|Enteric Hyperoxaluria
Interventions: DRUG: SYNB8802|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Artificial Intelligence in New Cardiac MR Markers for Congenital Heart Disease
Status: ENROLLING_BY_INVITATION
Conditions: Aortic Valve Disease|Pulmonary Valve Disease|Child, Only|Magnetic Resonance Imaging|Risk Stratification
Interventions: PROCEDURE: Valvuloplasty,
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sucrose as a Standard in Cesarean Section Surgical Wound Healing to Reduce Hospital Time
Status: ACTIVE_NOT_RECRUITING
Conditions: Surgical Wound Infection|Cesarean Wound; Dehiscence
Interventions: PROCEDURE: Clorhexidine soap|OTHER: Sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety, Tolerability, and Effects of GSK2374697 in Healthy Volunteers
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: GSK2376497|DRUG: 0.9% sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of the Relationship Between the Human Mesolimbic Reward System and Immune Functioning
Status: COMPLETED
Conditions: Immune Hepatitis
Interventions: BEHAVIORAL: Neuromodulation via fMRI Neurofeedback task|BIOLOGICAL: Hepatitis B vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Clinical Evaluation of Implantable Pump System For Safety And Delivery Accuracy In Patients Requiring Intrathecal Administration Of Morphine Sulfate For Chronic Pain
Status: COMPLETED
Conditions: Cancers|Chronic Pain
Interventions: DEVICE: Implantation of Morphine Sulfate delivering programmable pump
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbohydrate Fluids and Post Operative Nausea and Vomiting
Status: NOT_YET_RECRUITING
Conditions: Nausea, Postoperative|Vomiting, Postoperative
Interventions: OTHER: Carbohydrate drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety of Sanofi Pasteur's AVAXIM 80U Pediatric Vaccine Followed by Booster Dose
Status: COMPLETED
Conditions: Hepatitis A
Interventions: BIOLOGICAL: Hepatitis A vaccine AVAXIM 80U|BIOLOGICAL: Hepatitis A vaccine (HAVRIX 720)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of High-frequency Deep Diathermy on Heart Rate Variability in Women With Primary Dysmenorrhea
Status: COMPLETED
Conditions: Primary Dysmenorrhea|Dysmucorrhea
Interventions: DEVICE: High frequency therapy (5 minutes)|DEVICE: High frequency therapy (7 minutes)|DEVICE: High frequency therapy (9 minutes)|DEVICE: Superficial heat therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Tamsulosin on Postoperative Urinary Retention
Status: COMPLETED
Conditions: Postoperative Retention of Urine
Interventions: DRUG: Tamsulosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Anaplastic Thyroid Cancer and Follicular Thyroid Cancer-derived Exosomal Analysis Via Treatment of Lovastatin and Vildagliptin and Pilot Prognostic Study Via Urine Exosomal Biological Markers in Thyroid Cancer Patients
Status: COMPLETED
Conditions: Thyroid Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Recombinant Factor VIIa in Patients With Severe Bleeding Due to Trauma
Status: WITHDRAWN
Conditions: Acquired Bleeding Disorder|Trauma
Interventions: DRUG: activated recombinant human factor VII
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Selumetinib Sulfate in Treating Woman With Recurrent Low-Grade Ovarian Cancer or Peritoneum Cancer
Status: COMPLETED
Conditions: Borderline Ovarian Serous Tumor|Low Grade Ovarian Serous Adenocarcinoma|Micropapillary Serous Carcinoma|Primary Peritoneal Carcinoma|Primary Peritoneal Low Grade Serous Adenocarcinoma|Recurrent Borderline Ovarian Surface Epithelial-Stromal Tumor
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Selumetinib|DRUG: Selumetinib Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual Guidance in Regional Anesthesia
Status: COMPLETED
Conditions: Anesthesia, Local|Anesthesia|Anesthesia; Adverse Effect
Interventions: PROCEDURE: Regional Anesthesia Touhy|PROCEDURE: Regional Anesthesia Facet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of S-ketamine for Patients Undergoing Electroconvulsive Therapy (ECT)
Status: UNKNOWN
Conditions: Depression, Bipolar|Depression, Unipolar|Major Depressive Disorder|Manic-Depressive - Now Depressed
Interventions: DRUG: S-ketamine|DRUG: ketamine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transplantation of Autologous Bone Marrow Derived Stem Cells in Patients With Rheumatoid Arthritis
Status: UNKNOWN
Conditions: RheumatoId Arthritis|Osteoarthritis, Knee|Osteoarthritis, Hip
Interventions: BIOLOGICAL: Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes as Neoadjuvant Therapy for HER2-Negative Breast Cancer
Status: RECRUITING
Conditions: Breast Neoplasms
Interventions: PROCEDURE: Sentinel Lymph Node Biopsy (SLNB)|DRUG: Doxorubicin|DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: Tumor-draining lymph node-derived lymphocyte (LNL)|BIOLOGICAL: Interleukin-2|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment With Cannabis Oil Containing CBD, THC, CBDV or CBG vs. Placebo of Persons With ADHD
Status: TERMINATED
Conditions: ADHD|Hyperactivity|Attention Deficit
Interventions: DRUG: Cannabis oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a High-fat Meal on the Pharmacokinetics of SHR0302 and Mass Balance Study in Healthy Subjects
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: SHR0302
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label Study of Povetacicept in Subjects With Autoimmune Cytopenias
Status: RECRUITING
Conditions: Immune Thrombocytopenia|Idiopathic Thrombocytopenic Purpura|Warm Autoimmune Hemolytic Anemia|Cold Agglutinin Disease
Interventions: DRUG: povetacicept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiolabeled SMT-487 (Yttrium Y 90-DOTA-tyr3-octreotide) in Treating Patients With Refractory Small Cell Lung Cancer or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Lung Cancer
Interventions: RADIATION: yttrium Y 90-edotreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Withdrawal of Non-invasive Ventilation in Chronic Obstructive Pulmonary Disease (COPD) Patients With Acute Hypercapnic Respiratory Failure
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Hypercapnic Respiratory Failure
Interventions: DEVICE: BIPAP Synchrony
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized, Investigator-blinded, Parallel, Multi-center, Phase 3 Trial
Status: COMPLETED
Conditions: Bowel Preparation
Interventions: DRUG: CTP0303|DRUG: Orafang Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Repeat Dose Study With GSK1018921 to Assess Safety, Tolerability, Pharmacokinetics, Pharmacodynamics in Healthy Volunteers and Patients With Schizophrenia and to Evaluate Its Effect on PK of Midazolam.
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Glycine Transporter-1 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Cognitive Training Through Exercise After a First Schizophrenia Episode
Status: COMPLETED
Conditions: Schizophrenia|Schizophreniform Disorder|Schizoaffective Disorder
Interventions: BEHAVIORAL: Case management and supportive psychotherapy|BEHAVIORAL: Family psychoeducation|BEHAVIORAL: Cognitive training|BEHAVIORAL: Aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ST-100 as Treatment for Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: ST-100 Ophthalmic Solution|DRUG: Placebo Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Atezolizumab Administered in Combination With Bevacizumab and/or With Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: 5-FU|DRUG: Atezolizumab|DRUG: Bevacizumab|DRUG: Carboplatin|DRUG: Leucovorin|DRUG: Nab-paclitaxel|DRUG: Oxaliplatin|DRUG: Paclitaxel|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Investigation of the Pre-movement Facilitation of Agonist-antagonist Muscles and the Effect of the Feedforward Rehabilitation in Individuals With Hypermetria
Status: COMPLETED
Conditions: Spinocerebellar Atrophy (SCA)
Interventions: OTHER: Temporal electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: [KSR-001-P01]Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetic Characteristic of KSR-001
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: KSR-001|DRUG: KSR-004|DRUG: KSR-001-02|DRUG: KSR-001-03
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Human Tolerance of Oral Probiotic Streptococcus Salivarius K12
Status: NOT_YET_RECRUITING
Conditions: Strep Throat
Interventions: DIETARY_SUPPLEMENT: Oral probiotic Streptococcus salivarius K12 sachet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Spinal Anesthesia in Caesarean Section
Status: UNKNOWN
Conditions: Hypotension Drug-Induced|Cesarean Section Complications|Spinal Anesthetics Causing Adverse Effects in Therapeutic Use|Bradycardia
Interventions: DRUG: Levobupivacaine|DRUG: Bupivacaine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Palomid 529 in Patients With Neovascular Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: Palomid 529
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Muscle Relaxants in Parotidectomy Operation With Neuromonitoring
Status: COMPLETED
Conditions: Intubation; Difficult or Failed|Muscle Relaxation|Anesthesia Intubation Complication|Airway Complication of Anesthesia
Interventions: PROCEDURE: Group A - Muscle Relaxants Used|PROCEDURE: Group B - No Muscle Relaxants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Sodium Nitrite to Treat Arterial Aging
Status: COMPLETED
Conditions: Vascular Aging
Interventions: DRUG: Placebo|DRUG: Sodium Nitrite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Vision in TBI
Status: TERMINATED
Conditions: Brain Injuries|Visually Impaired Persons
Interventions: OTHER: Vision Restoration Therapy|BEHAVIORAL: NVT Eye Scanning Therapy|BEHAVIORAL: Eccentric Viewing Training|BEHAVIORAL: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Apoplectic Sequela With Acupuncture: a Randomized Controlled Study
Status: UNKNOWN
Conditions: Cerebral Infarction
Interventions: OTHER: acupuncture|BEHAVIORAL: rehabilitation|OTHER: acupuncture and rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Polymethyl Methacrylate CAD/CAM Crowns Versus Prefabricated Zirconia Crowns in Primary Molars
Status: ACTIVE_NOT_RECRUITING
Conditions: Caries of Infancy
Interventions: OTHER: preparation of the tooth to receive ready made zirconia crown|OTHER: preparation of the tooth to receive CAD CAM PMMA custom made crown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation the Effect of the Social-Communication Area Developmental Screening Test for Infants and Young Children Training Program Applied in Addition to the DIR/Floortime™ Therapy Program in Children With Developmental Risk
Status: RECRUITING
Conditions: Children With Developmental Risk
Interventions: OTHER: The DIR/Floortime™ Therapy Program|OTHER: The Social-Communication Area Developmental Screening Test for Infants and Young Children (SCASI) Training Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Galaxy Rapamycin Drug-Eluting Bioresorbable Coronary Stent System First-in-man Study
Status: UNKNOWN
Conditions: Heart Diseases
Interventions: DEVICE: Rapamycin Drug-Eluting Bioresorbable Coronary Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy and Durvalumab/Durvalumab Combo (Tremelimumab/Olaparid) for Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Small Cell Lung Cancer Extensive Stage|Small-cell Lung Cancer
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|DRUG: Olaparib Pill|RADIATION: Thoracic Radiotherapy|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study to Assess the Scan, Fit and Print Process for the Aveera "Patient Matched" CPAP Mask
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Aveera
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dietary Intervention in Obesity-related Glomerulopathy
Status: UNKNOWN
Conditions: Obesity|Glomerulopathy
Interventions: OTHER: Optisource® Plus: Very Low Calorie Diet treatment|OTHER: Hypocaloric Mediterranean Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of Glaucoma Eye Care Follow-Up Adherence in a High Risk Population
Status: COMPLETED
Conditions: Glaucoma
Interventions: BEHAVIORAL: Efficacy-patient navigator to improve follow-up adherence|BEHAVIORAL: Office-Based Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Contingency Management of Psychostimulant Abuse in the Severely Mentally Ill
Status: COMPLETED
Conditions: Drug Abuse|Schizophrenia|Bipolar Disorder|Major Depressive Disorder
Interventions: BEHAVIORAL: Contingency Management|BEHAVIORAL: Non Contingent Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Reduced Dose of Menomune® in Children Who Previously Received Meningococcal Diphtheria Toxoid Conjugate Vaccine
Status: COMPLETED
Conditions: Meningitis|Meningococcemia|Neisseria Meningitidis
Interventions: BIOLOGICAL: A/C/Y/W-135, Meningococcal Polysaccharide Vaccine (Menomune®)|BIOLOGICAL: A/C/Y/W-135, Meningococcal Polysaccharide Vaccine (Menomune®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Video-based Intervention Study to Prevent HIV/Sexually Transmitted Diseases (STDs) Among STD Clinic Patients
Status: COMPLETED
Conditions: HIV Infections|Sexually Transmitted Diseases
Interventions: DEVICE: Video-based HIV/STD prevention intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Knowledge of Nursing Theories of Teaching With Creative Drama in Fundamentals of Nursing Course Level and Perception of Nursing Profession
Status: ENROLLING_BY_INVITATION
Conditions: Explaining Nursing Theories Through Creative Drama
Interventions: OTHER: creative drama training|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Trial of R-GemOx Regimen in Previously Untreated Elderly Patients With DLBCL.
Status: UNKNOWN
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: R-GemOx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Physician Care for Home Hospital Patients
Status: COMPLETED
Conditions: Infection|Heart Failure|Chronic Obstructive Pulmonary Disease|Asthma|Gout Flare|Chronic Kidney Diseases|Hypertensive Urgency|Atrial Fibrillation Rapid|Anticoagulants; Increased
Interventions: OTHER: Remote Visit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhibition of Urinary Angiotensinogen and the Reduction of Blood Pressure by SGLT2 Inhibition in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Hypertension
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Injection of Tenoxicam Versus Arthrocentesis Alone in the Treatment of Temporomandibular Joint Osteoarthritis
Status: COMPLETED
Conditions: Arthrocentesis
Interventions: DRUG: Tenoxicam Injectable Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Angioplasty and DES in the Treatment of Subjects With Ischemic Infrapopliteal Arterial Disease
Status: COMPLETED
Conditions: Peripheral Arterial Diseases
Interventions: DEVICE: balloon angioplasty|DEVICE: drug eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-Center Trial to Evaluate an Internal Joint Stabilizer - Elbow
Status: COMPLETED
Conditions: Trauma|Chronic Elbow Dislocation
Interventions: DEVICE: Internal Joint Stabilizer - Elbow (IJS-E)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunoadsorption in Patients With Chronic Fatigue Syndrome Including Patients With Post-COVID-19 CFS
Status: RECRUITING
Conditions: ME/CFS|Post-COVID ME/CFS
Interventions: DEVICE: Immunoadsorption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DEPORRA-CoProst: Assessment of New Fluorescence Imagery Techniques Using Prostate Chips From Transurethral Resections
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Trans-urethral resection|DEVICE: Use of the FEMTO-ST institute medical device|DEVICE: Use of the Light-CT scanner
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH)
Status: COMPLETED
Conditions: Thrombocytopenia|Inherited Platelet Disorder
Interventions: DIAGNOSTIC_TEST: Validation of a new gene / protein variant implicated in familial CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety Study of Dexmedetomidine as an Additive to Local Anesthetics in Shoulder Surgery
Status: COMPLETED
Conditions: Drug Safety|Self Efficacy
Interventions: DRUG: dexmedetomidine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating a Proprietary Amino Acid Mixture (Enterade®) in Patients Receiving High-Dose Melphalan Conditioning Followed by Autologous Stem Cell Transplantation for Multiple Myeloma and Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Multiple Myeloma|Non-Hodgkin's Lymphoma
Interventions: DIETARY_SUPPLEMENT: Enterade|DIETARY_SUPPLEMENT: Placebo|OTHER: Standard Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety, Immunogenicity and Lot Comparability of DAPTACEL When Administered With Other Recommended Vaccine
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Whooping Cough|Polio|Haemophilus Influenzae Type b
Interventions: BIOLOGICAL: DAPTACEL® (Diphtheria and Tetanus Toxoids and Acellular Pertussis vaccine)|BIOLOGICAL: Pentacel: DTaP-IPV/Hib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Viaskin Pertussis Vaccine Trial
Status: COMPLETED
Conditions: Whooping Cough
Interventions: BIOLOGICAL: Viaskin PT 25 mcg|BIOLOGICAL: Viaskin PT 50 mcg|BIOLOGICAL: Viaskin PT Placebo|BIOLOGICAL: Boostrix™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Oral Ketone Body Supplementation in Patients With McArdle Disease
Status: COMPLETED
Conditions: McArdle Disease
Interventions: DIETARY_SUPPLEMENT: β-hydroxybuturate esters|DIETARY_SUPPLEMENT: Placebo drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Benign Paroxysmal Positional Vertigo (BPPV) in Older Patients
Status: UNKNOWN
Conditions: Benign Paroxysmal Positional Vertigo
Interventions: DRUG: Vitamin D|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study of BMS-512148 in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stroke Volume Variation and Pulse Pressure Variation as Predictors of Fluid Responsiveness During Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: PROCEDURE: Fluid loading
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Radiostereometric Analysis of Gap Balancing Versus Measured Resection for the Journey II Total Knee Replacement
Status: UNKNOWN
Conditions: Knee Osteoarthritis|Knee Arthroplasty
Interventions: PROCEDURE: Measured Resection|PROCEDURE: Gap Balancing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Low-level Light Therapy Using Photo-activated Modulation Ameliorates Cognitive Deficits
Status: UNKNOWN
Conditions: Mild Cognitive Impairment|Cerebral Blood Flow|Low-level Light Therapy|Brain Activity
Interventions: DEVICE: Low-level light therapy device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Therapeutic Use of BTX for Bruxism
Status: COMPLETED
Conditions: Myofascial Pain Syndrome|Myofascial Trigger Point Pain|Bruxism|Pain
Interventions: OTHER: Abobotulinumtoxin A injection for bruxism
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurophysiological Impact of a Fronto-temporal tDCS Stimulation in Healthy Subjects: a Multimodal Imaging Approach
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: real tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nitrocamptothecin Compared With Other Chemotherapy in Treating Patients With Recurrent or Refractory Cancer of the Pancreas
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: fluorouracil|DRUG: gemcitabine hydrochloride|DRUG: mitomycin C|DRUG: rubitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Turkish Version of the Mini-BESTest: Transcultural Adaptation and Validation Study in Stroke Patients
Status: UNKNOWN
Conditions: Stroke|Balance; Distorted
Interventions: DIAGNOSTIC_TEST: mini-BESTest (Mini-Balance Evaluation Systems Test)|DIAGNOSTIC_TEST: Berg Balance Scale|DIAGNOSTIC_TEST: Timed Up and Go Test|DIAGNOSTIC_TEST: Functional Reach Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Infliximab (Remicade) for Patients With Acute Kawasaki Disease
Status: COMPLETED
Conditions: Kawasaki Disease
Interventions: DRUG: Infliximab (Remicade)|BIOLOGICAL: Intravenous immunoglobulin (IVIG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Silymarin in Patients With Non-alcoholic Fatty Liver Disease - The SILIVER Trial
Status: UNKNOWN
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: Silymarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of GC33 and Sorafenib in Combination in Advanced or Metastatic Liver Cancer (Hepatocellular Carcinoma)
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: GC33(RO5137382)|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy Combined With Oxaliplatin and Fluorouracil Followed By Gemcitabine in Treating Patients With Locally Advanced, Unresectable Pancreatic Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Pancreas|Stage II Pancreatic Cancer|Stage III Pancreatic Cancer
Interventions: RADIATION: radiation therapy|DRUG: oxaliplatin|DRUG: fluorouracil|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Peri-Urethral Stimulation on Intra-Urethral Pressure
Status: RECRUITING
Conditions: Stress Urinary Incontinence
Interventions: DIAGNOSTIC_TEST: Urodynamic testing with and without pudendal nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Modified Dynamic Needle Tip Positioning vs Conventional Long-axis In-plane in Radial Artery Cannulation
Status: COMPLETED
Conditions: Ultrasound|Arterial Catheterization|Coronary Artery Disease
Interventions: PROCEDURE: Modified dynamic needle tip positioning under ultrasound-guidance|PROCEDURE: Long-axis technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of OSI-7904L Versus 5-FU/LV as Treatment in Patients With Biliary Tract Cancer
Status: COMPLETED
Conditions: Locally Advanced or Metastatic Adenoca of the Biliary Tract
Interventions: DRUG: OSI-7904L|DRUG: 5-Fluorouracil/Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Sympathetic Denervation in Patients With Drug-resistant Hypertension and Symptomatic Atrial Fibrillation
Status: UNKNOWN
Conditions: Hypertension|Atrial Fibrillation
Interventions: PROCEDURE: renal sympathetic denervation|DRUG: drug|PROCEDURE: Direct-Current Cardioversion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Difluprednate in the Treatment of Inflammation Following Ocular Surgery (ST-601-003)
Status: COMPLETED
Conditions: Inflammation
Interventions: DRUG: Difluprednate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Dried Cranberry Powder in Women With Dry OAB
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Dried Cranberry|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Text Messaging in Patients on Adjuvant Endocrine Therapy for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Adherence, Medication|Side Effect
Interventions: BEHAVIORAL: BETA-Text text messaging intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anatomical Feasibility of the Off-the-shelf E-nside Multibranch Stent Graft System for Thoracoabdominal and Para-renal Aortic Aneurysms.(E-nside Study)
Status: COMPLETED
Conditions: Aortic Aneurysm, Thoracoabdominal|Para-renal Aortic Aneurysms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigate the Maximum Tolerated Dose of Vandetanib and Concurrent Whole Brain Radiotherapy (WBRT) in Patients With Non-small Cell Lung Cancer (NSCLC) and Brain Metastases
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: ZD6474 (Vandetanib)|RADIATION: Whole Brain Radiotherapy (WBRT)|DRUG: ZD6474|DRUG: ZD6474
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Artificial Intelligence ECG With ECG Devices to Detect Hypertrophic Cardiomyopathy Distinct From Athlete's Heart
Status: RECRUITING
Conditions: Hypertrophic Cardiomyopathy|Athlete Heart
Interventions: DIAGNOSTIC_TEST: 12-Lead ECG|DIAGNOSTIC_TEST: Apple Smart Watch Single Lead ECG|DIAGNOSTIC_TEST: AliveCor KardiaMobile 6-Lead ECG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: STARBRITE: A Randomized Pilot Trial of BNP-Guided Therapy in Patients With Advanced Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DEVICE: Brain Natriuretic Peptide Levels -- Diagnostic testing|OTHER: clinical assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy and Safety of Finerenone and Spironolactone in the Treatment of Primary Aldosteronism
Status: NOT_YET_RECRUITING
Conditions: Primary Aldosteronism|Hypertension
Interventions: DRUG: Finerenone|DRUG: Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aneurysma Hernia Study - Incidence of Incisional Hernias After Abdominal Aortic Aneurysm Repair
Status: COMPLETED
Conditions: Incisional Hernia|Abdominal Aortic Aneurysm
Interventions: PROCEDURE: PRINCIPLES technique|PROCEDURE: Conventional group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Short Infusion Versus Prolonged Infusion of Ceftolozane-tazobactam Among Patients With Ventilator Associated-pneumonia
Status: UNKNOWN
Conditions: Ventilator-associated Pneumonia
Interventions: DRUG: 1 hour infusion|DRUG: 4 hours infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Diabetic Foot Ulcers Through Cleaner Feet
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: Chlorhexidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of KN019 in Rheumatoid Arthritis Patients With an Inadequate Response to Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: KN019, 5mg/kg|BIOLOGICAL: KN019, 10 mg/kg|BIOLOGICAL: Placebo|COMBINATION_PRODUCT: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of an Internet-based Dialectical Behaviour Therapy-informed Skills Training for Adult Drinkers
Status: RECRUITING
Conditions: Alcohol Drinking
Interventions: BEHAVIORAL: Internet-based dialectical behaviour therapy-informed skills training|BEHAVIORAL: Monthly health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Competitive Transfer of αCD19-TCRz-CD28 and αCD19-TCRz-CD137 CAR-T Cells for B-cell Leukemia/Lymphoma
Status: UNKNOWN
Conditions: Hematopoietic/Lymphoid Cancer|Adult Acute Lymphoblastic Leukemia in Remission|B-cell Adult Acute Lymphoblastic Leukemia|B-cell Chronic Lymphocytic Leukemia|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Refractory Chronic Lymphocytic Leukemia|Stage III Adult Diffuse Large Cell Lymphoma|Stage III Chronic Lymphocytic Leukemia|Stage III Grade 1 Follicular Lymphoma|Stage III Grade 2 Follicular Lymphoma|Stage III Grade 3 Follicular Lymphoma|Stage III Mantle Cell Lymphoma|Stage IV Adult Diffuse Large Cell Lymphoma|Stage IV Chronic Lymphocytic Leukemia|Stage IV Grade 1 Follicular Lymphoma|Stage IV Grade 2 Follicular Lymphoma|Stage IV Grade 3 Follicular Lymphoma|Stage IV Mantle Cell Lymphoma
Interventions: BIOLOGICAL: anti-CD19 CAR-T|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of OCV-501 in Patients With Acute Myeloid Leukemia (AML) (Extension From Study 311-10-001)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: OCV-501
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib With or Without Hydroxychloroquine in Chemo-Naive Advanced NSCLC and (EGFR) Mutations
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Erlotinib|DRUG: Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of DA9301 on Tablet Computer-Induced Asthenopia
Status: COMPLETED
Conditions: Asthenopia
Interventions: DIETARY_SUPPLEMENT: DA9301 (Vaccinium uliginosum extract)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Therapeutic Effect of Acupressure Therapy and Iberogast ® (STW-5) in Children With Functional Nausea
Status: COMPLETED
Conditions: Functional Nausea
Interventions: OTHER: Acupressure|OTHER: Placebo-band|DRUG: Iberogast|OTHER: Placebo-drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Biomechanical Effects of Manual Therapy - A Feasibility Study
Status: COMPLETED
Conditions: Low Back Pain, Mechanical
Interventions: OTHER: Manual therapy|OTHER: Evidence-informed home management booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Video-Based Games for Upper Limb Rehabilitation in Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Rehabilitation
Interventions: DEVICE: VGBT with Nintendo® Wii and LMC games|BEHAVIORAL: NDT-based upper limb rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ketoprofen With or Without Vaginal Isonicotinic Acid Hydrazide Prior to Hysterosalpingography
Status: COMPLETED
Conditions: Infertility, Female
Interventions: DRUG: Ketoprofen + INH|DRUG: Ketoprofen + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CBT With Disulfiram and Contingency Management
Status: COMPLETED
Conditions: Cocaine Abuse
Interventions: DRUG: disulfiram|DRUG: Placebo|BEHAVIORAL: Placebo plus Contingency Management|DRUG: Disulfiram plus Contingency Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Non-Traumatic Binder for Temporary Abdominal Wall Closure
Status: UNKNOWN
Conditions: Abdominal Trauma|Abdominal Injury|Abdominal Infection|Abdominal Sepsis|Abdominal Abscess|Abdominal Aneurysm|Abdominal Compartment Syndrome|Peritonitis
Interventions: DEVICE: Experimental: ABRO™ Binder Arm|DEVICE: Placebo Comparator: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT