pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Reducing Pain During Orogastric Tube Placement in Preterm
Status: COMPLETED
Conditions: Preterm|Pain|Nursing Caries
Interventions: OTHER: The effect of usıng breast mılk pacıfıer ın reducıng the paın that occurs durıng orogastrıc tube ınsertıon ın preterm newborns|OTHER: The effect of usıng sucrose pacıfıer ın reducıng the paın that occurs durıng orogastrıc tube ınsertıon ın preterm newborns|OTHER: The effect of usıng pacıfıer ın reducıng the paın that occurs durıng orogastrıc tube ınsertıon ın preterm newborns
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reliability and Validity of iPhone Application for OBER
Status: COMPLETED
Conditions: Reliability and Validity|Smartphone|Iliotibial Band Syndrome
Interventions: DEVICE: iPhone measurement application|DEVICE: Bubble inclinometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: CPI-0209 Plus Carboplatin in Patients With Platinum Sensitive Recurrent Ovarian Cancer
Status: RECRUITING
Conditions: Recurrent Ovarian Cancer
Interventions: DRUG: CPI-0209|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Cyclophosphamide in Patients With Life-Threatening Systemic Lupus Erythematosus or Antiphospholipid Antibody Syndrome
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus|Antiphospholipid Antibody Syndrome
Interventions: DRUG: Cyclophosphamide|DRUG: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Using Vitamin D to Reduce Oral Mucosal Inflammation in Chemotherapy Patients With Oral Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Oral Squamous Cell Carcinoma|Oral Mucositis
Interventions: DRUG: Alfacalcidol Oral Solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir and Sofosbuvir/Velpatasvir in Adults With Chronic HCV Infection Who Have Not Previously Received Treatment With Direct-Acting Antiviral Therapy
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: SOF/VEL/VOX|DRUG: SOF/VEL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Botulinum Toxin Type A Against Placebo to Treat Spasticity in the Arm After a Stroke
Status: COMPLETED
Conditions: Post-stroke Spasticity of the Upper Limb
Interventions: DRUG: IncobotulinumtoxinA (400 Units)|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of CDX-1401 in Combination With Poly-ICLC and Pembrolizumab, in Previously Treated Advanced Solid Tumor Patients
Status: WITHDRAWN
Conditions: Non Small Cell Lung Cancer|Advanced Triple Negative Breast Cancer|Small Cell Lung Cancer|Urothelial Cancer|Mesothelioma|Malignant Melanoma
Interventions: DRUG: Pembrolizumab|BIOLOGICAL: CDX-1401|BIOLOGICAL: Poly-ICLC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Neuropeptide Y in Clinical Trial in Level Two Trauma Patients for PTSD and Acute Stress Disorder
Status: UNKNOWN
Conditions: Stress Disorders, Post-Traumatic|Stress Disorders, Traumatic, Acute
Interventions: DRUG: Neuropeptide Y|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Applications of (S)-[18F]FBFP PET/CT in Healthy Volunteers and Patients With Central Nervous System Diseases
Status: RECRUITING
Conditions: Patients With Central Nervous System Diseases
Interventions: DIAGNOSTIC_TEST: (S)-[18F]FBFP PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nutritional Adaptations to Physical or Sedentary Activities in Youth
Status: WITHDRAWN
Conditions: Passive Video Games (PVG)|Active Video Games (AVG)|Exercise (EX)
Interventions: BEHAVIORAL: experimental condition: Passvice Video game; Avtive Video game; Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Determining the Prognostic Value of Continuous Intrathecal Infusion
Status: COMPLETED
Conditions: Lumbar Post-Laminectomy Syndrome|Chronic Low Back Pain|Vertebral Compression Fracture|Failed Back Surgery Syndrome
Interventions: OTHER: Continuous intrathecal prognostic infusion test|DRUG: Bupivacaine|DRUG: Fentanyl|DRUG: Placebo|DEVICE: Intrathecal Drug Delivery System (IDDS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low Pressure Versus Standard Pressure Pneumoperitoneum in Laparoscopic Nephrectomy
Status: NOT_YET_RECRUITING
Conditions: Non-Functioning Kidney|Renal Cell Carcinoma
Interventions: PROCEDURE: Laparoscopic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effect of Epidural Stimulation on Muscle Activation and Sensory Perception
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DEVICE: Intraoperative Parameter Testing|DEVICE: Proprioception Testing During Stimulation|DEVICE: Gait Analysis During Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Chimeric Natriuretic Peptide Versus Placebo in Stable Heart Failure and Moderate Renal Dysfunction
Status: WITHDRAWN
Conditions: Heart Failure|Renal Insufficiency
Interventions: DRUG: CD-NP|DRUG: 5% Dextrose in Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation vs. Laser Hemorrhoidoplasty Procedure for Hemorrhoidal Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemorrhoids
Interventions: DEVICE: Radiofrequency ablation|DEVICE: Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of OCE-205 in Participants With Cirrhosis With Ascites Who Developed Hepatorenal Syndrome-Acute Kidney Injury
Status: COMPLETED
Conditions: Cirrhosis|Ascites|Hepatorenal Syndrome|Acute Kidney Injury
Interventions: DRUG: OCE-205|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Ascending Dose Study of BTZ043
Status: COMPLETED
Conditions: Tuberculosis|Tuberculosis, Pulmonary|Bacterial Infections|Lung Diseases|Mycobacterium Infections
Interventions: DRUG: BTZ-043|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetic Care Self-Management Mobile Health Application Among Diabetes Mellitus Clients in Malaysia
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Diabetes Care Self-Management Mobile Health Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multicenter Study on Laparoscopic Versus Open PANP-TME for Male Mid-low Rectal Cancer Patients
Status: UNKNOWN
Conditions: Rectum Neoplasms
Interventions: PROCEDURE: L-PANP-TME|PROCEDURE: O-PANP-TME
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Foam Rolling and Orthopaedic Manual Physical Therapy in Athletes
Status: COMPLETED
Conditions: Athletic Injuries
Interventions: OTHER: Foam Rolling (FR)|OTHER: Control Group (CG)|OTHER: Orthopaedic Manual Physical Therapy Group (OMPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Assessing Intestinal Microbiota Diversification and Changes After Travel to South(East) Asia From the US
Status: COMPLETED
Conditions: Dysbiosis
Interventions: OTHER: Screening Criteria Review|OTHER: Pre-Travel Questionnaire|OTHER: Pre-Travel Stool Specimen Collection|OTHER: Short-Term Post-Travel Questionnaire|OTHER: Short-Term Post-Travel Stool Specimen Collection|OTHER: Long-Term Post-Travel Questionnaire|OTHER: Long-Term Post-Travel Stool Specimen Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Centralized IIS-based Reminder/Recall to Increase Childhood Influenza Vaccination Rates_2nd Trial in Colorado
Status: COMPLETED
Conditions: Reminder Systems|Influenza Vaccines
Interventions: BEHAVIORAL: Reminders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Shoe Lifts for Leg Length Inequality in Adults With Knee or Hip Symptoms
Status: COMPLETED
Conditions: Leg Length Inequality|Osteoarthritis, Knee|Osteoarthritis, Hip
Interventions: DEVICE: Shoe lift correction for leg length inequality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics Study of LY03005
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: LY03005|DRUG: Placebo|OTHER: Meal|DRUG: Pristiq
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine Prevent POCD
Status: UNKNOWN
Conditions: Necrosis of Femoral Head|Knee Osteoarthritis
Interventions: DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Propranolol Hydrochloride in the Treatment of Metastatic STS
Status: UNKNOWN
Conditions: Malignant Soft Tissue Sarcoma
Interventions: DRUG: Propranolol Hydrochloride|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic
Status: COMPLETED
Conditions: Alopecia Areata|Alopecia Totalis|Alopecia Universalis|Alopecia Areata (& Ophiasis)|Alopecia Barbae|Alopecia Diffuse|Autoimmune Diseases|Autoimmune Hyperthyroidism|Autoimmune Hypothyroidism|Diabetes Mellitus, Type 1|Ulcerative Colitis|Inflammatory Bowel Diseases|Crohn Disease|Rheumatoid Arthritis|Down Syndrome|Atopic Dermatitis|Atopic Asthma|Atopic Rhinitis|Vitiligo|Psoriasis|Ankylosing Spondylitis|Multiple Sclerosis|Lupus Erythematosus|COVID-19 Pandemic|Vaccine Reaction|Infections|Anemia, Pernicious
Interventions: OTHER: Exposure of interest
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sintilimab Injection Combined With Inlyta in Fumarate Hydratase- Deficient Renal Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Renal Cell|Fumarate Hydratase Deficiency|Immunotherapy
Interventions: DRUG: Sintilimab injection plus Inlyta treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Empowerment of Lung and Heart-lung Transplant Patients
Status: UNKNOWN
Conditions: Lung Transplantation|Heart-Lung Transplantation|"Rehabilitation"|Psychotherapy|Exercise Training
Interventions: BEHAVIORAL: resource-activating behavioural training programme|BEHAVIORAL: Relaxation training|BEHAVIORAL: Intensified anaerobic exercise training|BEHAVIORAL: Moderate aerobic exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Homeless Care Management App
Status: COMPLETED
Conditions: Substance Use Disorders|Mental Health Impairment|Health Behavior|Adherence, Patient
Interventions: BEHAVIORAL: In-Person Case Management at Homeless Recovery Program|BEHAVIORAL: Unlimited Smartphone|BEHAVIORAL: Smartphone Based Case Management (SPCM) app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics of MEDI9929 (AMG 157) in Adolescents With Mild to Moderate Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: MEDI9929, 140 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Auricular Point Acupressure to Self-Manage Chronic Pain or Aromatase Inhibitor Musculoskeletal Symptoms in Breast Cancer Survivors: Effectiveness and Scientific Underpinnings
Status: COMPLETED
Conditions: Aromatase Inhibitor|Musculoskeletal Symptoms|Postmenopausal Breast Cancer Survivors
Interventions: OTHER: APA|OTHER: Sham APA control|OTHER: Education control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Popliteal Block for Postoperative Pain in Knee-ankle Soft Tissue Surgery in Cerebral Palsy
Status: COMPLETED
Conditions: Postoperative Pain|Cerebral Palsy
Interventions: PROCEDURE: Popliteal block|DRUG: Sevoflurane|DEVICE: Ultrasound|OTHER: Plaster cover|DRUG: bupivacaine|OTHER: Laryngeal mask airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rhythmical Massage Compared With Heart Rate Variability Biofeedback in Women With Menstrual Pain (Dysmenorrhea)
Status: COMPLETED
Conditions: Primary Dysmenorrhea
Interventions: OTHER: Rhythmical massage|BEHAVIORAL: HRV biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Finding Study to Assess Safety and Efficacy of Stem Cells in Liver Cirrhosis
Status: COMPLETED
Conditions: Alcoholic Liver Cirrhosis
Interventions: BIOLOGICAL: Allogeneic Mesenchymal Stem Cells|BIOLOGICAL: Allogeneic Mesenchymal Stem Cells|BIOLOGICAL: Allogeneic Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Stepped Palliative Care in Patients With Advanced Lung Cancer DF/HCC SOCIAL-BEHAVIORAL RESERACH PROTOCOL
Status: TERMINATED
Conditions: Lung Cancer
Interventions: OTHER: Stepped Palliative Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cardiac Function in Severe Aneurysmal Subarachnoid Haemorrhage Patients
Status: COMPLETED
Conditions: Aneurysmal Subarachnoid Haemorrhage|World Neurosurgeon Federation Score ≥ III
Interventions: PROCEDURE: Echocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Effectiveness and Safety of Libicare® in Women With Low Arousal and Sexual Desire Levels
Status: WITHDRAWN
Conditions: Female Sexual Interest/Arousal Disorder
Interventions: DIETARY_SUPPLEMENT: Libicare|DIETARY_SUPPLEMENT: active control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Single-Arm Clinical Trial Evaluating the Safety and Efficacy of Amisulpride in Treating Patients With Schizophrenia and Schizoaffective Disorder Who Have Treatment-Resistant Positive Symptoms
Status: WITHDRAWN
Conditions: Schizophrenia, Treatment-Resistant
Interventions: DRUG: Amisulpride 50 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sofosbuvir/Velpatasvir Fixed Dose Combination for 12 Weeks in Participants With Chronic HCV
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: SOF/VEL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study to Investigate the Frequency of Possible Bacterial Entry Into the Bloodstream (Bacteremia) and Infectious Complications Associated With the Use of the Spyglass Cholangioscopy System During ERCP (Endoscopic Retrograde Cholangiopancreatography).
Status: UNKNOWN
Conditions: Bile Duct Stricture|Choledocholithiasis
Interventions: OTHER: Blood draw for culture
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Biomarkers of Response to Mepolizumab Treatment in Patients With Nasal Polyps With or Without Bronchial Asthma
Status: RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps|Asthma
Interventions: DRUG: Mepolizumab 100 MG [Nucala]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Prospective, Multi-Center Evaluation of a Powered Vascular Stapler in Video-Assisted Thoracoscopic Lobectomies
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DEVICE: Video-Assisted Thoracoscopic Lobectomy with powered vascular stapler
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Efficacy and Safety of DWP16001 in Combination With Metformin in Patients With Type 2 Diabetes.
Status: COMPLETED
Conditions: T2DM (Type 2 Diabetes Mellitus)
Interventions: DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Of The Effect Of Supine And Prone Position On The Ultrasonographic Airway Measurements
Status: UNKNOWN
Conditions: Airway Edema|Obstructive Sleep Apnea|Respiratory Complication
Interventions: DIAGNOSTIC_TEST: preoperative airway ultrasonography|DIAGNOSTIC_TEST: postoperative airway ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: The Effect of Pressure Controlled Ventilation on the Pulmonary Mechanics in Prone Position Using the Wilson Frame: A Comparison With Volume Controlled Ventilation
Status: COMPLETED
Conditions: Herniation of Lumbar Vertebral Disc
Interventions: PROCEDURE: volume control|PROCEDURE: pressure control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Donor Stem Cell Transplant in Treating Patients With High-Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|DRUG: methotrexate|DRUG: sirolimus|DRUG: tacrolimus|PROCEDURE: allogeneic stem cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Avoidance of Futile Excisions Through Skin Tele-triage
Status: ENROLLING_BY_INVITATION
Conditions: Melanoma (Skin)|Telemedicine
Interventions: DIAGNOSTIC_TEST: Single Assessor Teledermatological triage (TDT)|DIAGNOSTIC_TEST: 2 people Teledermatological triage (TDT)|DIAGNOSTIC_TEST: 3 people Teledermatological triage (TDT)|DIAGNOSTIC_TEST: 5 people Teledermatological triage (TDT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Recurrent Inguinal Hernia Treatment - Lichtenstein Versus Laparoscopic Totally Extraperitoneal Preperitoneal Hernioplasty
Status: COMPLETED
Conditions: Recurrent Inguinal Hernia
Interventions: PROCEDURE: Lichtenstein hernioplasty|PROCEDURE: Laparoscopic TEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of the CO-OP Approach for Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Cognitive Orientation
Interventions: OTHER: CO-OP approach|OTHER: NDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 40-week Study to Evaluate TNX-102 SL 5.6 mg Taken Daily at Bedtime in Patients With PTSD
Status: COMPLETED
Conditions: PTSD
Interventions: DRUG: TNX-102 SL 5.6 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Waveform and Flow Traces From Mechanical Insuflattion:Exsufflation (MI:E) be Used to Identify Laryngeal Responses to MI:E and Thus Optimise Treatment Algorithms?
Status: RECRUITING
Conditions: Neuromuscular Diseases
Interventions: DEVICE: Mechnical Insufflation:Exsufflation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Drug Exposure of Single Ascending Doses of BMS-986369 and the Effect of Food on the BMS-986369 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: BMS-986369
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capacitation-associated Protein Tyrosine Phosphorylation as a Possible Biomarker of Sperm Selection
Status: RECRUITING
Conditions: Sperm Capacitation
Interventions: OTHER: Analysis of capacitation-associated tyrosine phosphorylation in human sperm by flow cytometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Platelet-rich Plasma Injection for Ulnar Neuropathy at Elbow
Status: COMPLETED
Conditions: Ulnar Neuropathy at Elbow
Interventions: DRUG: platelet-rich plasma|DRUG: 5% dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketoprofen 10% Cream for Treatment of Pain Associated With Mild to Moderate Acute Soft Tissue Injury
Status: COMPLETED
Conditions: Sprain|Strain|Acute Soft Tissue Injury
Interventions: DRUG: Topical Ketoprofen 10% Cream|DRUG: Topical Placebo Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Distribution of PF-06372865 in the Brain of Healthy Volunteers Using Positron Emission Tomography and a Radioactive Tracer Following Oral Administration of One Dose of PF-06372865
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06372865|DRUG: PF-06372865|DRUG: PF-06372865
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Efficacy of Investigational OTC Eye Drops
Status: COMPLETED
Conditions: Ophthalmic Solutions
Interventions: DRUG: F# 13418-148 Eye Drops|DRUG: F#13418-158 Eye Drops|DRUG: F# PF-004390 Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Measuring Dysphagia After ACDF Surgery Through A Novel Wearable Sensor
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Spine Fusion
Interventions: PROCEDURE: Anterior Cervical Discectomy & Fusion|DEVICE: Application of ADAM mechanoacoustic skin sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ICU Family Communication Study
Status: COMPLETED
Conditions: Depression|Depressive Symptoms|Anxiety|Stress Disorders, Post-Traumatic|ICU Hospitalization|Care and Treatment in ICU
Interventions: BEHAVIORAL: Facilitator-Based intervention|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: T-Cell Infusion, Aldesleukin, and Utomilumab in Treating Patients With Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: COL6A3 Positive|HLA-A*0201 Positive Cells Present|PRAME Positive|Recurrent Ovarian Carcinoma
Interventions: BIOLOGICAL: Aldesleukin|DRUG: CD8-Positive T-Lymphocyte|DRUG: Cyclophosphamide|PROCEDURE: Leukapheresis|BIOLOGICAL: Utomilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone-To-Implant Contact At 4- And 6-Week Healing Stages in Implants With Different Surfaces.
Status: COMPLETED
Conditions: Implant Geometry
Interventions: PROCEDURE: Implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Yi-Zhi-An-Shen Granules For Older Adults With Amnestic Mild Cognitive Impairment
Status: COMPLETED
Conditions: Cognitive Dysfunction
Interventions: DRUG: Yi-Zhi-An-Shen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Efficacy, Safety, and Tolerability Study of Canagliflozin in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Alone or in Combination With a Sulphonylurea
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: Canagliflozin 100mg|DRUG: Canagliflozin 300mg|DRUG: Metformin|DRUG: Sulphonylurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma
Status: RECRUITING
Conditions: Eosinophilic Asthma|Asthma; Eosinophilic|Asthma Attack
Interventions: DRUG: Dexpramipexole Dihydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peginterferon Alfa-2b in Younger Patients With Craniopharyngioma That is Recurrent or Cannot Be Removed By Surgery
Status: TERMINATED
Conditions: Childhood Craniopharyngioma
Interventions: BIOLOGICAL: peginterferon alfa-2b|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Surgical/Medical Oncology Collaboration for Breast Cancer Treatment Planning: Pilot Testing the Impact of Continuing Education and Patient Care Planning
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Carevive CPS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Postoperative Pain and Skin Closure Methods After Cesarean Section
Status: TERMINATED
Conditions: Pregnancy
Interventions: PROCEDURE: Insorb staples skin closure|PROCEDURE: Monocryl skin closure|PROCEDURE: Vicryl skin closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Off-site Assistance on Success Rate of Selective Cannulation During hands-on ERCP Training
Status: RECRUITING
Conditions: ERCP Training|Biliary Tract Diseases|Pancreatic Diseases
Interventions: PROCEDURE: Off-site assistance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Feasibility and Usability of COVID-19 Antigen RDTs in Uganda
Status: COMPLETED
Conditions: COVID-19 Pandemic
Interventions: DIAGNOSTIC_TEST: PMC Sure Status COVID-19 Antigen Test|DIAGNOSTIC_TEST: Acon Flowflex COVID-19 Antigen Home Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluate the Effect of Graft and Membrane on Healing of Apicomarginal Defects
Status: UNKNOWN
Conditions: Apicomarginal Defects
Interventions: PROCEDURE: Periapical surgery with autograft and collagen membrane|PROCEDURE: Periapical surgery with collagen membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Environmental Distractions on SCAT6 Outcomes
Status: COMPLETED
Conditions: Concussion, Brain|Mild Traumatic Brain Injury
Interventions: OTHER: SCAT6|OTHER: Visual/ Auditory Distraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safety and Performance of a Vascular Patch in Pediatric Patients Undergoing Bidirectional Cava-pulmonary Anastomosis
Status: COMPLETED
Conditions: Heart Defects, Congenital
Interventions: DEVICE: Xeltis Vascular Patch, Model COR-VP-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Gemcitabine,Cisplatin and Radiation Versus Cisplatin and Radiation in Cancer of the Cervix
Status: COMPLETED
Conditions: Cancer of Cervix
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin|RADIATION: Brachytherapy|RADIATION: Pelvic radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TANGO-LIVER Three Arm Nuclear Growth Observation in Liver Surgery
Status: NOT_YET_RECRUITING
Conditions: Liver Metastases|Liver Cancer|Liver Neoplasms|Liver Metastasis Colon Cancer
Interventions: PROCEDURE: PVE|PROCEDURE: LVD|PROCEDURE: ALPPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Efficacy and Safety of LTP001 in Pulmonary Arterial Hypertension
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: LTP001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Wound Care and Reduction of Wound Complications by Use of AQUACEL® Ag Surgical Dressing in MIS TKA
Status: COMPLETED
Conditions: Postoperative Complication
Interventions: OTHER: AQUACEL® Ag Surgical dressing (study group)|OTHER: Sofra-Tulle® dressing (control group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TactiCath® Contact Force Ablation Catheter Study for Atrial Fibrillation Post Approval Study
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: TactiCath Quartz treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clarithromycin Treatment to Prevent Sepsis Progression in CAP (REACT)
Status: RECRUITING
Conditions: Community-acquired Pneumonia
Interventions: DRUG: Clarithromycin 500mg|DRUG: Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TransHealthGUIDE: Transforming Health for Gender-Diverse Young Adults
Status: RECRUITING
Conditions: Transgender Persons|Health Services for Transgender Persons|Gender Identity
Interventions: BEHAVIORAL: Interactive educational digital platform for transgender and gender-diverse (TGD) young adults and caregivers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Photodynamic Therapy With Levulan® +/- Topical Retinoid Pre-Treatment In The Treatment Of Actinic Keratoses
Status: COMPLETED
Conditions: ACTINIC KERATOSES
Interventions: DRUG: Tazorac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Bioscaffolds in Conjunction With Negative Pressure Therapy: A Prospective Randomized Double-Blinded Trial
Status: WITHDRAWN
Conditions: Foot Ulcer, Diabetic
Interventions: DEVICE: PriMatrix
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Etoposide, Cyclophosphamide, Thalidomide, Celecoxib, and Fenofibrate in Relapsed or Progressive Cancer
Status: COMPLETED
Conditions: Central Nervous System Tumor, Pediatric|Leukemia|Lymphoma|Neuroblastoma|Sarcoma|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: celecoxib|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: fenofibrate|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Oral Tobacco as a Harm Reduction Method for Smokers
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: OTHER: Camel Snus|OTHER: Marlboro Snus|OTHER: Stonewall|OTHER: Ariva|OTHER: General Snus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Peer-to-Peer (VP2P) Support Mentoring for Juvenile Idiopathic Arthritis (JIA): A Pilot RCT
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: BEHAVIORAL: Virtual Peer-to-Peer Support Mentoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Non-interventional Study of Ectoin Nasal Douche (END01) in Patients With Acute Viral Rhinosinusitis
Status: COMPLETED
Conditions: Acute Rhinosinusitis
Interventions: DRUG: Xylometazoline Nasal Spray|DEVICE: Ectoin Nasal Douche
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of a Seasonal Trivalent Split, Inactivated Influenza Vaccine
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: Influenza vaccine, split inactivated|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Intervention in Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Use Disorder|Eligible to go Into the MRI Scanner|Short-term Abstinence From Alcohol Use (2 Week Abstinent)
Interventions: DEVICE: Transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Tolerability and Pharmacokinetics of Lacidipine With and Without the Co-administration of Telmisartan in Female and Male Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lacidipine|DRUG: Telmisartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Glove for Hand and Arm Rehabilitation After Stroke
Status: COMPLETED
Conditions: Stroke, Acute|Cerebral Infarction
Interventions: DEVICE: Neofect RAPAEL Smart Glove
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study Of OCU400 Gene Therapy for the Treatment Of Retinitis Pigmentosa
Status: RECRUITING
Conditions: Retinitis Pigmentosa
Interventions: GENETIC: Sub-Retinal Administration of OCU400-301
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in Pediatric Patients With Cushing's Disease
Status: RECRUITING
Conditions: Cushing's Disease
Interventions: DRUG: LCI699
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy People to Test How Well Repeated Doses of BI 3032950 Are Tolerated
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 3032950|DRUG: Placebo matching BI 3032950
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Evaluation of Testosterone Gel (1%)
Status: COMPLETED
Conditions: Primary or Secondary Hypogonadism|Constitutional Delay in Growth and Puberty (CDGP)
Interventions: DRUG: Testosterone Gel (1%)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fertility Preservation by Ovarian and Oocyte Cryopreservation
Status: UNKNOWN
Conditions: Female Patients Aged 5-35 Prior to Systemic Chemotherapy|With Significant Risk of Ovarian Toxicity
Interventions: PROCEDURE: ovarian transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study To Assess Differential Sensitivity Of 2 Spatial Working Memory Tests In Schizophrenics Treated With Risperidone
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorders
Interventions: DRUG: Risperidone 2 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy For Patients Being Considered For Organ Transplant Who Are at Risk For PTLD
Status: TERMINATED
Conditions: Lymphoproliferative Disorder
Interventions: BIOLOGICAL: Inactivated EBV-infected vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TBTC Study 23B:Intensive PK of the Nelfinavir Rifabutin Interaction in Patients With HIV-TB
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: Nelfinavir|DRUG: Rifabutin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Obinutuzumab and Venetoclax in Relapsed or Refractory DLBCL
Status: COMPLETED
Conditions: Lymphoma, Large B-Cell, Diffuse
Interventions: DRUG: Venetoclax|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Alemtuzumab (Campath) and Dose-Adjusted EPOCH-Rituximab (DA-EPOCH-R) in Relapsed or Refractory Diffuse Large B-Cell and Hodgkin Lymphomas
Status: COMPLETED
Conditions: Hodgkin Lymphoma|Diffuse Large B-Cell Lymphoma
Interventions: BIOLOGICAL: Campath|BIOLOGICAL: Rituximab|DRUG: EPOCH
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atypical Antipsychotics for Continuation and Maintenance Treatment After an Acute Manic Episode
Status: COMPLETED
Conditions: Bipolar I Disorder
Interventions: DRUG: Valproate|DRUG: Lithium|DRUG: Risperidone|DRUG: Olanzapine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib+Sintilimab+TACE vs. Lenvatinib+TACE for Advanced HCC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma Non-resectable
Interventions: DRUG: Lenvatinib, sintilimab plus TACE|DRUG: Lenvatinib plus TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interview Study of Adult and Child Patients and Parents of Children With Swelling Due to Nephrotic Syndrome.
Status: RECRUITING
Conditions: Fluid Overload|Glomerulosclerosis, Focal Segmental|Edema|Membranous Nephropathy|Minimal Change Disease|Minimal Change Nephrotic Syndrome|IgM Nephropathy|Nephrotic Syndrome|Glomerular Disease|Nephrotic Syndrome, Minimal Change|Nephrotic Syndrome in Children|Nephrotic Syndrome With Edema (Diagnosis)|FSGS
Interventions: BEHAVIORAL: Interview
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PRIORITY-CONNECT 2 Pilot Trial
Status: RECRUITING
Conditions: Liver Cancer|Pancreas Cancer|Oesophageal Cancer|Gastric Cancer|Colorectal Cancer
Interventions: BEHAVIORAL: Preoperative Exercise|BEHAVIORAL: Postoperative Exercise|DIETARY_SUPPLEMENT: Preoperative Nutrition|DIETARY_SUPPLEMENT: Postoperative Nutrition|BEHAVIORAL: Preoperative Psychology|BEHAVIORAL: Postoperative Psychology|OTHER: Preoperative Nursing|OTHER: Postoperative Nursing|OTHER: Preoperative Peer Support Group|OTHER: Postoperative Peer Support Group|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Switching Antipsychotics: Abrupt Discontinuation Versus Overlap
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Clozapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Safety of Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: bimatoprost 0.01% ophthalmic solution|DRUG: bimatoprost 0.03% ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Nasal Isotonic Solution Irigation on Healthy Athletes' Nasal Flow and Nasal Obstruction Exercise Outcomes
Status: RECRUITING
Conditions: Nasal Obstruction|Nasal Disease
Interventions: DIETARY_SUPPLEMENT: Nasal irrigation with seawater isotonic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Deep Trigger Point Dry Needling on Strength Measurements of the Gluteus Medius Musculature
Status: COMPLETED
Conditions: Trigger Point|Muscle Weakness
Interventions: OTHER: Trigger Point Dry Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydrocortisone and Fludrocortisone for Critical Illness-related Corticosteroid Insufficiency
Status: RECRUITING
Conditions: Critical Illness Related Corticosteroids Insufficiency
Interventions: DRUG: Investigational products administration|DRUG: Placebo administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of DE-114 Ophthalmic Solution in Patients With Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: DE-114 ophthalmic solution|DRUG: Placebo ophthalmic solution|DRUG: Olopatadine Hydrochloride 0.1% Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: PD-1 Monoclonal Antibody, Lenvatinib and TACE in the Treatment of HCC
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma Non-resectable
Interventions: COMBINATION_PRODUCT: PD-1 mAb combined with TACE and lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Ventilation in Preterm Infants
Status: RECRUITING
Conditions: Premature Birth|Respiratory Distress Syndrome|Ventilator Lung; Newborn
Interventions: DIAGNOSTIC_TEST: Titration procedure|DIAGNOSTIC_TEST: Electrical impedance tomography|DIAGNOSTIC_TEST: Lung and diaphragm ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Resynchronization Therapy, Dyspnea and Exercise Tolerance in Patients With Congestive Heart Failure (CHF)
Status: TERMINATED
Conditions: Congestive Heart Failure
Interventions: DEVICE: Active Cardiac Resynchronization Therapy (CRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Kinesiotaping in Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: DEVICE: Kinesiotaping|OTHER: Sham taping|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT