pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Prevalence of fAmilial hypobetalipopRoTeinemIa in psychiaTrIc pOpulatioN (PARTITION)
Status: COMPLETED
Conditions: Familial Hypobetalipoproteinemia
Interventions: DIAGNOSTIC_TEST: Psychiatric population
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Etrasimod Versus Placebo for the Treatment of Moderately Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Etrasimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Virtual Cardiometabolic Health Program for African Immigrants: The Afro-DPP Program
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 2|PreDiabetes|Hypertension|High Blood Pressure|High Blood Sugar|Obesity|Overweight|Overweight and Obesity|Overweight or Obesity
Interventions: BEHAVIORAL: The Diabetes Prevention Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Efficacy and Safety Study of Lanabecestat (LY3314814) in Early Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer´s Disease
Interventions: DRUG: Lanabecestat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Economic Benefits of Topical Wound Oxygen Therapy in the Treatment of Chronic Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: TWO2 Device|DEVICE: Placebo Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study on Laser Ablation of Symptomatic Benign Thyroid Masses
Status: COMPLETED
Conditions: Thyroid Nodule|Thyroid Cancer|Thyroid Neoplasms|Nodular Goiter
Interventions: PROCEDURE: Laser Ablation of Thyroid Nodule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SerpinPC in Participants With Hemophilia B (HemB) With Inhibitors
Status: RECRUITING
Conditions: Hemophilia B With Inhibitor|Hemophilia B
Interventions: DRUG: SerpinPC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiolabeled Monoclonal Antibody in the Detection and Staging of Patients With Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: PROCEDURE: immunoscintigraphy|RADIATION: technetium Tc 99m epratuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: iFAAM: The Impact of Proton-pump Inhibitors (Antacids) on Threshold Dose Distributions
Status: COMPLETED
Conditions: Food Allergy
Interventions: DRUG: Omeprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Panama and El Salvador Children's Oseltamivir Study
Status: TERMINATED
Conditions: Influenza|Human Influenza
Interventions: DRUG: Oseltamivir phosphate suspension|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of tDCS on Depressive Symptoms,Neurocognitive Function and HRV in Unipolar Depression and Bipolar Depression
Status: COMPLETED
Conditions: Depressive Disorder, Major|Depression, Bipolar|Electricity; Effects
Interventions: DEVICE: tDCS over DLPFC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Pemetrexed Plus Cisplatin in Patients With Refractory Soft Tissue Sarcoma
Status: UNKNOWN
Conditions: Sarcoma
Interventions: DRUG: Pemetrexed, cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label - Personalized Therapeutic Neuromodulation for Anhedonic Depression
Status: NOT_YET_RECRUITING
Conditions: Treatment Resistant Depression
Interventions: DEVICE: Active TBS-DLPFC|DEVICE: TBS-DMPFC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study With OAB Assessing the Safety and Activity of hMaxi-K Gene Transfer
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Placebo (PBS-20% sucrose)|DRUG: hMaxi-K
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of an Acellular Osteochondral Graft for Cartilage LEsions Pilot Trial
Status: TERMINATED
Conditions: Articular Cartilage Injury
Interventions: DEVICE: Kensey Nash Corp. Cartilage Repair Device|PROCEDURE: Microfracture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic SCT Of Pts With SCID And Other Primary Immunodeficiency Disorders
Status: TERMINATED
Conditions: Severe Combined Immunodeficiency Disease|Severe Primary Immunodeficiency Disorder|Undefined T Cell Deficiency Disorder|Wiskott-Aldrick Syndrome
Interventions: BIOLOGICAL: Campath -1H|DRUG: Fludarabine|BIOLOGICAL: Anti-CD45|PROCEDURE: Stem cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Repetitive Transcranial Magnetic Stimulation for Improvement of Memory in Older Adults With TBI
Status: COMPLETED
Conditions: Brain Injuries, Traumatic|Repetitive Transcranial Magnetic Stimulation|Memory Deficits|Aging
Interventions: DEVICE: Repetitive Transcranial magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antithymocyte Globulin and Cyclosporine to Treat Myelodysplasia
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: Antithymocyte globulin|DRUG: Cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on Antibiotic-Lock in Tenckhoff Catheter for Relasping and Repeat Peritonitis
Status: RECRUITING
Conditions: Peritoneal Dialysis-associated Peritonitis
Interventions: DRUG: antibiotic lock|DRUG: conventional IP antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Paroxetine on Cardiovascular Function in Septic Patients
Status: RECRUITING
Conditions: Septic Shock|Sepsis
Interventions: DRUG: Paroxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Resistance ExerciSe on Muscle Mass in GlioblaSToma Survivors
Status: ENROLLING_BY_INVITATION
Conditions: Glioblastoma Multiforme of Brain|Brain Cancer
Interventions: BEHAVIORAL: Circuit-based resistance exercise (CRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sorafenib Tosylate in Treating Patients With Recurrent Aggressive Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Hepatosplenic T-cell Lymphoma|Peripheral T-cell Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma
Interventions: DRUG: sorafenib tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SDOH-Homecare Intervention Focus Team (SHIFT) Trial to Improve Stroke Outcomes
Status: NOT_YET_RECRUITING
Conditions: Stroke|Social Determinants of Health
Interventions: BEHAVIORAL: SHIFT team intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Anterioposterior Weight Shifting Training With Visual Biofeedback in Subacute Stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: anterioposterior Weight Shifting Training with Visual Biofeedback|BEHAVIORAL: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Effect of Aprotinin of Transfusion Requirements in Patients Undergoing Surgical Procedures for Lung or Esophageal Cancer
Status: TERMINATED
Conditions: Blood Loss, Surgical
Interventions: DRUG: Trasylol (Aprotinin, BAYA0128)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pragmatic Assessment of Influenza Vaccine Effectiveness in the DoD
Status: ACTIVE_NOT_RECRUITING
Conditions: Influenza|Influenza-like Illness|Influenza Vaccines
Interventions: BIOLOGICAL: Egg based influenza vaccines|BIOLOGICAL: Recombinant influenza vaccines|BIOLOGICAL: Cell-culture based influenza vaccines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Red Blood Cell Transfusion in the Ambulatory Setting: Impact on Home Functional Status
Status: COMPLETED
Conditions: Red Blood Cell Transfusions|Anemia|Hematology|Oncology|Ambulatory Care
Interventions: OTHER: No-Transfuse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PA Tolerability, Safety and Pharmacokinetics in Healthy Volunteers
Status: COMPLETED
Conditions: Infections, Respiratory
Interventions: DRUG: Potentiator of antibiotics (PA)|OTHER: Placebo PA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Vitabreath Pilot in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: COPD|Dyspnea
Interventions: DEVICE: Vitabreath Device|OTHER: Pursed Lip Breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Carfilzomib, Lenalidomide, Dexamethasone and Belantamab Mafodotin in Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib, Lenalidomide, Dexamethasone, Belantamab Mafodotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Group CA-CBT Intervention to Reduce Psychological Distress of Earthquake Survivors
Status: RECRUITING
Conditions: Psychological Distress|Depressive Symptoms|Well-Being, Psychological
Interventions: BEHAVIORAL: Culturally Adapted Cognitive Behavioral Therapy (CA-CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Clinical Trial With the Iron Chelator Deferiprone in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Deferiprone 20mg|DRUG: Placebo|DRUG: Deferiprone 30mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Spatial Navigation Using Non-Invasive Brain Stimulation
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Alzheimer's Disease
Interventions: DEVICE: Transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Permanent Atrial fibriLLAtion Outcome Study Using Dronedarone on Top of Standard Therapy
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: DRUG: Dronedarone|DRUG: Placebo (for Dronedarone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Biodistribution of [89Zr]Zr-DFO-APAC in Subjects with PAOD/CLI and Healthy Volunteers (Acronyms: 89Zr = Zirconium-89, DFO = Desferrioxamine, APAC = AntiPlatelet AntiCoagulant, PET/CT = Positron Emission Tomography/Computed Tomography)
Status: RECRUITING
Conditions: Peripheral Arterial Occlusive Disease|Critical Limb Ischemia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Gastric Retentive Carbidopa/ Levodopa in Parkinson's Patients; a One Year, Open Label, Safety Extension Study
Status: WITHDRAWN
Conditions: Parkinson's Disease
Interventions: DRUG: AP-CD/LD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wellbeing After Stroke (WAterS): Supporting Adjustment and Wellbeing After Stroke
Status: COMPLETED
Conditions: Stroke|Psychological Distress|Cognitive Dysfunction|Communication Disorders|Psychological Adjustment
Interventions: OTHER: Acceptance and Commitment Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vetsibular Socket Therapy Versus Buser's Technique
Status: COMPLETED
Conditions: Dental Implant Failed
Interventions: OTHER: VST and immediate implants|OTHER: Buser technique and early implants placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Contoura Vision Outcomes Programmed Using the Manifest Refraction Verses Using Phorcides Planning Software in Patients With Oblique Astigmatism
Status: TERMINATED
Conditions: Myopia|Astigmatism
Interventions: DEVICE: Contoura LASIK with Phorcides planning strategy|DEVICE: Contoura LASIK with manifest refraction planning strategy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Determine the Relative Bioavailability, Single and Repeat Dose Pharmacokinetics, Safety and Tolerability of BOS172767 Enantiomers in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BOS172767 enantiomer E1 or E2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of NPC-08 is to Treat for Newly-Diagnosed Malignant Glioma and Recurrent Glioblastoma Multiforme
Status: COMPLETED
Conditions: Malignant Glioma
Interventions: DRUG: NPC-08
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Near-infrared Fluorescence Lymphatic Imaging Assessment of Lymphatic Response to Pneumatic Back/Neck Lymphatic Drainage Delivered by a Pneumatic Manual Lymphatic Drainage Device
Status: COMPLETED
Conditions: Neck Pain|Back Pain
Interventions: DRUG: Indocyanine green (ICG) dye|DEVICE: NIRF-LI imaging|DEVICE: Neuroglide pad
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UNITO-001- Study in HRR/PDL1 Positive MPM/NSCLC
Status: RECRUITING
Conditions: Lung Cancer|Mesothelioma
Interventions: DRUG: niraparib and dostarlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanism Research of Tinnitus Based on Electroencephalogram and Acoustic Therapy Intervention
Status: UNKNOWN
Conditions: Tinnitus, Subjective
Interventions: OTHER: music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Interactions Between Faldaprevir, Itraconazole, Atorvastatin and Rosuvastatin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Itraconazole|DRUG: Atorvastatin|DRUG: Faldaprevir|DRUG: Rosuvastatin|DRUG: Faldaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pilates in Risk Fall in Older Population
Status: COMPLETED
Conditions: Falling Injury
Interventions: OTHER: Pilates and fall prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Effect of VX-770 on Hyperpolarized Helium-3 Magnetic Resonance Imaging in Subjects With Cystic Fibrosis and the G551D Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: VX-770|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ocular Rosacea Biome Study
Status: RECRUITING
Conditions: Ocular Rosacea|Antimicrobial Resistance
Interventions: DRUG: Doxycycline 40 MG ( 20mg twice daily)|DRUG: Doxycycline 200 MG ( 100 mg twice daily)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: HIV/STI Prevention for Adolescents With Substance Use Disorders in Treatment
Status: COMPLETED
Conditions: HIV|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: STYLEnS|BEHAVIORAL: Health Promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: L-citrulline for Prevention of Sequelae of Acute Lung Injury in Pediatrics Undergoing Cardiopulmonary Bypass for Heart Defects
Status: COMPLETED
Conditions: Acute Lung Injury
Interventions: DRUG: L-citrulline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of the Amaranth Medical MAGNITUDE Bioresorbable Drug-Eluting Coronary Stent (RENASCENT III)
Status: UNKNOWN
Conditions: Coronary Artery Disease|Myocardial Ischemia
Interventions: DEVICE: AmM MAGNITUDE Bioresorbable Drug-Eluting Coronary Scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Vismodegib in Patients With Relapsed/Refractory Acute Myelogenous Leukemia and Relapsed Refractory High-Risk Myelodysplastic Syndrome
Status: TERMINATED
Conditions: Myelodysplastic Syndromes, Myelogenous Leukemia, Acute
Interventions: DRUG: cytarabine|DRUG: vismodegib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of DM001 in Patients With Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Breast Neoplasms|Carcinoma, Non-Small-Cell Lung|Solid Carcinoma
Interventions: DRUG: DM001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension to a Randomized, Double-blind, Placebo Controlled Study of LCQ908 in Subjects With Familial Chylomicronemia Syndrome.
Status: TERMINATED
Conditions: Familial Chylomicronemia Syndrome (FCS) (HLP Type I)
Interventions: DRUG: LCQ908
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Two Rates of Activation of Miniscrew-Supported Upper Jaw Expander in Adolescents
Status: COMPLETED
Conditions: Palatal Expansion Technique|Malocclusion|Posterior Crossbite|Maxillary Hypoplasia
Interventions: DEVICE: Miniscrew-Supported Maxillary Expander- Slow activation|DEVICE: Miniscrew-Supported Maxillary Expander- Rapid activation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Acceptability of Mindfulness-based Resilience Training for Rural Law Enforcement Officers
Status: RECRUITING
Conditions: Problem Drinking|Aggression|Stress, Psychological
Interventions: BEHAVIORAL: Mindfulness-Based Resilience Training (MBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of High and Low Pulse Energy Dusting Protocols Using Holmium: YAG-laser in Flexible Ureteroscopy for Renal Stones Treatment
Status: COMPLETED
Conditions: Renal Stone
Interventions: DEVICE: Holmium Yag laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare Efficacy, Safety and Immunogenicity of HLX02 and Herceptin in Previously Untreated HER2 +Overexpressing Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: HLX02|BIOLOGICAL: Herceptin®|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modified Video-assisted Thoracoscopic Surgery (VATS) Lobectomy for Early-stage Non-small Cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DEVICE: VATS lobectomy using modified equipments|PROCEDURE: VATS lobectomy using less staples|PROCEDURE: Standard VATS lobectomy|PROCEDURE: Open lobectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Safety and Effectiveness of JUVÉDERM VOLUX™ XC Injectable Gel for Restoring Jawline Definition
Status: COMPLETED
Conditions: Jawline Definition
Interventions: DEVICE: VOLUX XC|OTHER: No-treatment control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study of SDX-7320 in Patients With Advanced Refractory or Late-Stage Solid Tumors
Status: COMPLETED
Conditions: Advanced Malignancy|Advanced Solid Tumors|Neoplasm|Metastasis
Interventions: DRUG: SDX-7320
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Motexafin Gadolinium for the Treatment of Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Motexafin Gadolinium Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of a Distal Colonoscope Attachment to Increase Detection of Sessile Serrated Adenomas
Status: COMPLETED
Conditions: Sessile Serrated Adenoma
Interventions: DEVICE: Endocuff Vision Assisted Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Sorafenib Induced Autophagy Using Hydroxychloroquine in Hepatocellular Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Cancer
Interventions: DRUG: Sorafenib (SOR)|DRUG: Hydroxychloroquine (HCQ)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: White Noise and Therapeutic Touch on Pain and Comfort Level in Newborns During Heel Lance
Status: UNKNOWN
Conditions: Pain, Acute|Newborn
Interventions: BEHAVIORAL: white noise|BEHAVIORAL: therapeutic touch|BEHAVIORAL: white noise and therapeutic touch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Front-of-package Labels on Weight Bias Among Latines
Status: RECRUITING
Conditions: Weight Prejudice
Interventions: BEHAVIORAL: Numerical label|BEHAVIORAL: Interpretive text-only label|BEHAVIORAL: Interpretive magnifying glass icon label|BEHAVIORAL: Separated interpretive magnifying glass icon label
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Improvement of Pain Following Robotic Sacrocolpopexy and Rectocele Repair for Pelvic Organ Prolapse
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: DRUG: Bupivacaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Fluzoparib±Apatinib Versus Placebo Maintenance Treatment in Patients With Advanced Ovarian Cancer Following Response on First-Line Platinum-Based Chemotherapy
Status: UNKNOWN
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma
Interventions: DRUG: Fluzoparib; Apatinib|DRUG: Fluzoparib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Sequencing of Pembrolizumab (MK-3475) and Standard Platinum-based Chemotherapy in First-Line NSCLC
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: MK-3475|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Confirmatory Clinical Trial to Evaluate the Safety and Efficacy of AG1321001 in Chronic Cougher
Status: COMPLETED
Conditions: Cough
Interventions: DRUG: AG1321001(drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sedation Strategies for Therapeutic Bronchoscopy 2
Status: UNKNOWN
Conditions: Bronchoscopy|Sedation
Interventions: DRUG: Dexmedetomidine|DRUG: Remifentanil|DEVICE: Laryngeal mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Talaporfin Sodium Photodynamic Therapy to Treat Advanced Age Related Macular Disease
Status: TERMINATED
Conditions: Macular Degeneration|Choroidal Neovascularization
Interventions: DRUG: Talaporfin Sodium (LS11) Photodynamic Therapy (PDT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Indocyanine Green Tracer Using in Laparoscopic Radical Gastrectomy for Locally Advanced Gastric Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer|Surgery
Interventions: PROCEDURE: ICG near-infrared imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sub-study to Spinal Cord Stimulation to Restore Cough
Status: COMPLETED
Conditions: Spinal Cord Injuries|Spinal Cord Diseases|Paralysis|Central Nervous System Diseases|Cough
Interventions: PROCEDURE: Spinal Cord Stimulation|DEVICE: Expiratory Muscle Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Study of the DePuy Low Contact Stress (LCS) Complete Total Knee System
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee
Interventions: DEVICE: L.C.S. Complete Knee (DePuy Low Contact Stress Complete Knee System)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melatonin-Micronutrients for Osteopenia Treatment Study
Status: COMPLETED
Conditions: Osteoporosis|Osteopenia
Interventions: DIETARY_SUPPLEMENT: Fiber Pill|DIETARY_SUPPLEMENT: Melatonin, Strontium citrate, Vitamins D3 and K2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 3-AP and Gemcitabine as Second-Line Therapy in Treating Patients With Stage III or Stage IV Recurrent Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: triapine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of OC-01 in Adult Chinese With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: Varenicline Tartrate Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Althera® Versus Nutramigen / Cow's Milk Intolerance
Status: COMPLETED
Conditions: Allergy
Interventions: OTHER: Infant Formula Feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Leridistim Compared With Filgrastim in Treating Older Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Anemia|Leukemia|Neutropenia|Thrombocytopenia
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: leridistim|DRUG: cytarabine|DRUG: daunorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Therapeutic Effect of Two Fluoride Varnishes on White Spot Lesions: a Clinical Study
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: sodium fluoride|DRUG: sodium fluoride calcium fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Comparing Two Bladder Instillations for IC/BPS
Status: COMPLETED
Conditions: Interstitial Cystitis|Bladder Pain Syndrome
Interventions: DRUG: Bladder instillation WITH triamcinolone acetonide|DRUG: Bladder instillation WITHOUT triamcinolone acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ultrasound-Guided Dry Needling Therapy and Exercise in Piriformis Muscle Syndrome
Status: COMPLETED
Conditions: Piriformis Muscle Syndrome|Dry Needling|Ultrasonography|Ultrasound Guided Dry Needling|Exercise Treatment
Interventions: PROCEDURE: ultrasound guided dry needling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Selumetinib in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma
Status: TERMINATED
Conditions: Recurrent Adult Diffuse Large Cell Lymphoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Selumetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wool Clothing for the Management of Childhood Atopic Dermatitis (DESSINE2)
Status: RECRUITING
Conditions: Dermatitis, Atopic
Interventions: OTHER: wool clothing|OTHER: standard clothing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Foley With Oxytocin Versus Foley no Oxytocin for Induction of Labor
Status: COMPLETED
Conditions: Labor; Forced or Induced, Affecting Fetus or Newborn
Interventions: DRUG: Oxytocin|DEVICE: Transcervical Foley catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supported Speed Treadmill Training Exercise Program (SSTTEP) for Marginally Ambulatory Children With Cerebral Palsy
Status: UNKNOWN
Conditions: Cerebral Palsy
Interventions: BEHAVIORAL: Partial body weight support treadmill training|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility, Acceptability, and Efficacy of the Sleep Move Stand Study
Status: COMPLETED
Conditions: Physical Inactivity|Sedentary Behavior|Sleep|Cognitive Function
Interventions: BEHAVIORAL: Education|BEHAVIORAL: Health coaching|BEHAVIORAL: Activity Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Mindfulness Based Cognitive Therapy for Chronic Pain and Comorbid Unipolar Depression
Status: UNKNOWN
Conditions: Major Depressive Disorder|Dysthymic Disorder|Depressive Disorder NOS|Chronic Pain
Interventions: BEHAVIORAL: Mindfulness Based Cognitive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-bacterial Potential of Nano Calcium Hydroxide as an Intracanal Medication
Status: RECRUITING
Conditions: Endodontic Disease|Pulp Disease, Dental
Interventions: DRUG: Calcium hydroxide|DRUG: nano calcium hydroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Pharmacokinetics of Microdose Midazolam, Dabigatran, Pitavastatin, Atorvastatin and Rosuvastatin in Diabetic Patients
Status: RECRUITING
Conditions: Diabetes
Interventions: DRUG: The combinations of 10 µg midazolam, 375 µg dabigatran etexilate, 10 µg pitavastatin, 50 µg rosuvastatin, and 100 µg atorvastatin were administered to diabetic patients on an empty stomach.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ciclosporin in the Management of New Type 1 Reactions in Leprosy
Status: COMPLETED
Conditions: Leprosy
Interventions: DRUG: Ciclosporin|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of a Web-based Program to Help Parents of Middle School Students Effectively Communicate With Their Children About Substance Use
Status: COMPLETED
Conditions: Substance Use|Parenting|Communication
Interventions: BEHAVIORAL: Media Ready Parent|BEHAVIORAL: Active Control Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety of RNS60 in Large Vessel Occlusion Stroke Patients Undergoing Endovascular Thrombectomy
Status: COMPLETED
Conditions: Stroke, Ischemic
Interventions: DRUG: RNS60|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Addressing Kinesiophobia in Post-Meniscoplasty Patients Through Progressive Muscle Relaxation Training and Acupressure
Status: COMPLETED
Conditions: Meniscus Tear
Interventions: OTHER: Enhanced Care with PMRT and Acupressure|OTHER: standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of CIMT vs Mirror Therapy Effect in Infarcted CVA Patients for Improving Hand Functions
Status: ACTIVE_NOT_RECRUITING
Conditions: Infected Joint
Interventions: DIAGNOSTIC_TEST: Constraint-Induced Movement Therapy|OTHER: Mirror Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Influence of Power and Wavelength on Photobiomodulation Therapy for Muscle Performance in Healthy Subjects
Status: COMPLETED
Conditions: Low Level Laser Therapy|Photobiomodulation|Performance|Sport
Interventions: OTHER: Photobiomodulation|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety Confirmation Study of Pemetrexed Plus Cisplatin in Patients With Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Malignant Pleural Mesothelioma
Interventions: DRUG: pemetrexed|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Steroid Tapering on Functional Capacity and Neurocognition
Status: WITHDRAWN
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Dexamethasone acetate|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Healthy Tubal Ligated Women to Evaluate Pharmacodynamics, Safety and Pharmacokinetics of BAY1002670
Status: COMPLETED
Conditions: Leiomyoma
Interventions: DRUG: BAY1002670|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Atrial Fibrillation and Characterization of Blood Platelet
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Electrocardiogram (ECG)|BIOLOGICAL: Blood sampling from the cephalic vein|BIOLOGICAL: Blood sampling from the femoral vein|BIOLOGICAL: First blood sampling from left atrium|PROCEDURE: Atrial stimulation|BIOLOGICAL: Second blood sampling from left atrium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Peri-implant Tissues on the Galimplant Anti-rotational Slim Abutment.
Status: ACTIVE_NOT_RECRUITING
Conditions: Teeth Absent|Tooth-loss|Tooth Extraction|Dental Implant
Interventions: OTHER: Slim abutment|OTHER: Standard abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: IMP4297 DDI (Drug-Drug Interaction)Trial in Healthy Male Volunteers
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: IMP4297 40 mg|DRUG: IMP4297 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Using rTMS to Explore Neural Mechanisms of Stress-Induced Opioid Use
Status: WITHDRAWN
Conditions: Stress|Opioid-use Disorder
Interventions: DRUG: Placebo oral tablet|DRUG: Yohimbine + Hydrocortisone|DEVICE: sham rTMS|DEVICE: active rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Exploratory Trial to Evaluate the Efficacy and Safety of D565H Twice Daily Versus D565 Once Daily
Status: UNKNOWN
Conditions: Glaucoma, Primary Open Angle|Ocular Hypertension
Interventions: DRUG: D565H(Latanoprost 25㎍/㎖)|DRUG: D565(Latanoprost 50㎍/㎖)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The BurnAlong Pilot Study for Adolescent and Young Adult Cancer Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer|Cancer Metastatic|Neoplasms|Breast Cancer|Lung Cancer|Thyroid Cancer|Lymphoma|Lymphoma, Non-Hodgkin|Hodgkin Lymphoma|Leukemia|Sarcoma|Skin Cancer|Bone Cancer|Gynecologic Cancer|Pancreas Cancer|Multiple Myeloma|Colorectal Cancer|Gastrointestinal Cancer|Prostate Cancer|Glioblastoma|Brain Cancer|Head and Neck Cancer
Interventions: BEHAVIORAL: Virtual group based physical activity (BurnAlong) and Social Media Discussion Board
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The ExTINGUISH Trial of Inebilizumab in NMDAR Encephalitis
Status: RECRUITING
Conditions: Autoimmune Encephalitis|Encephalitis
Interventions: DRUG: Inebilizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Oral Anticoagulation With Vitamin K Antagonists - The thrombEVAL Study Programme
Status: COMPLETED
Conditions: Anticoagulant Antagonists, Vitamin K and Other Coagulants Causing Adverse Effects in Therapeutic Use|Atrial Fibrillation|Venous Thromboembolism
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Single-ascending Oral Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-281959 / ACT-246475 in Healthy Male Subjects
Status: COMPLETED
Conditions: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics
Interventions: DRUG: 5 mg ACT-281959 prodrug formulation I (Group A)|DRUG: 20 mg ACT-281959 prodrug formulation I (Group B)|DRUG: ACT-281959 prodrug formulation I (Groups C to G doses to be defined)|DRUG: ACT-281959 prodrug formulation II (Group G dose to be defined)|DRUG: ACT-246475 (Group G dose to be defined)|DRUG: Placebo (Groups A to F)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Adipocyte-Driven Mechanism For Weight Regain After Weight Loss: The Yo-Yo Effect
Status: COMPLETED
Conditions: Obesity|Weight Loss|Diet
Interventions: OTHER: Meal replacement diet using Modifast|OTHER: Normal diet combined with Modifast diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Chiauranib in Patients With Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Chiauranib|DRUG: Albumin-paclitaxel Injection|DRUG: Gemcitabine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Traumatic Brain Injury With Hyperbaric Oxygen Therapy
Status: COMPLETED
Conditions: Brain Injury, Chronic
Interventions: OTHER: Hyperbaric oxygen @ 2.4 ATA|OTHER: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 2b Study of GC4711 in Combination With SBRT for Nonmetastatic Pancreatic Cancer
Status: TERMINATED
Conditions: SBRT|Borderline Resectable Pancreatic Cancer|Unresectable Pancreatic Cancer
Interventions: DRUG: Drug GC4711|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subacromial Impingement Syndrome Approach Using High Intensity Laser Therapy
Status: COMPLETED
Conditions: Subacromial Impingement
Interventions: DEVICE: iLux Laser|DEVICE: Sham ilux Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Resistant Starch on Insulin Sensitivity and Beta Cell Function in Subjects With Prediabetes
Status: UNKNOWN
Conditions: Prediabetes
Interventions: DIETARY_SUPPLEMENT: Resistant Starch|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PHRU CoV01 A Trial of Triazavirin (TZV) for the Treatment of Mild-moderate COVID-19
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: Triazavirin (Riamilovir)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Candela 1064nm:Nd:YAG Laser for Skin Tightening
Status: COMPLETED
Conditions: Localized Lipodystrophy
Interventions: DEVICE: 1064 nm Nd:YAG laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-FRONTal Brain STability, Key for Action Against Disability in AGing
Status: UNKNOWN
Conditions: Cognitive Impairment|Motoric Cognitive Risk Syndrome
Interventions: BEHAVIORAL: Physical exercise (PE)|DEVICE: Transcranial current stimulation (tCS)|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PRF for Treating Maxillary Gingival Recession
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Gingival coverage using coronally advanced flap and a connective tissue graft|PROCEDURE: Gingival coverage using coronally advanced flap and platelet rich fibrin membranes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT