pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Efficacy and Safety of Lenvatinib Combined With Sindilimab and Nab-paclitaxel in the First-line Treatment for Recurrent and Metastatic Triple Negative Breast Cancer: a Phase Ib/IIa Clinical Trial.
Status: NOT_YET_RECRUITING
Conditions: Breast Neoplasms
Interventions: DRUG: Sindilimab|DRUG: Nab-paclitaxel|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Gemcitabine, Carboplatin With or Without Trastuzumab in Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Gemcitabine|DRUG: Carboplatin|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial for Evaluating Both Safety and Preliminary Efficacy of a Single Infusion of Stimulated Autologous CD4+T Cells in Patients With Relapsing- Remitting Multiple Sclerosis
Status: TERMINATED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: BIOLOGICAL: Autologous CD4+T cells stimulated and expanded ex vivo by a MOG peptide modified by the introduction of a thioreductase motif into the flanking residues of the T cell epitope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Investigate the Creation of Physiological Rhythm by Closed Loop Stimulation in hEart Failure pAtients With chronoTropic incompEtence
Status: COMPLETED
Conditions: Heart Failure|CPX
Interventions: DEVICE: Cardiac Resynchronization therapy device with Closed Loop Stimulation (CLS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RCT on the Effect of Endometrial Injury on Ongoing Pregnancy Rate in Subfertile Women Undergoing IVF
Status: COMPLETED
Conditions: Subfertility
Interventions: PROCEDURE: Endometrial aspiration by pipelle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Group Blended Transdiagnostic CBT Protocol for Emotional Disorders
Status: COMPLETED
Conditions: Anxiety Disorders|Depressive Disorder
Interventions: BEHAVIORAL: Group Blended Transdiagnostic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aurora Kinase Inhibitor AT9283 in Treating Patients With Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkins Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: Aurora kinase inhibitor AT9283
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Miltefosine for Mucosal Leishmaniasis
Status: COMPLETED
Conditions: Leishmaniasis
Interventions: DRUG: miltefosine 2.5 mg/kg/day for 28 days
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3D Model - Classification of Thoracic and Lumbar Spinal Fractures.
Status: NOT_YET_RECRUITING
Conditions: Lumbar Spine Disease
Interventions: OTHER: Education through a 3D model|OTHER: Education through a traditional pedagogical support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Incidence of Malignant and Premalignant Endometrial Polyp in Asymptomatic and Symptomatic Postmenopausal Women
Status: UNKNOWN
Conditions: Endometrial Polyp.|Malignant and Pre-malignant Changes in the Polyp
Interventions: PROCEDURE: Hysteroscopic polypectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ofloxacin vs. Gentamicin as Prophylaxis Prior Transrectal Biopsy of Prostate
Status: UNKNOWN
Conditions: Infection
Interventions: DRUG: ofloxacin|DRUG: gentamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of MK-6096 as Adjunctive Therapy in Participants With Major Depressive Disorder And Partial Response to Antidepressant Monotherapy (MK-6096-022)
Status: TERMINATED
Conditions: Major Depressive Disorder, Recurrent
Interventions: DRUG: Filorexant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stretch-Shortening Cycle Exercise: Potential Implications For Children With Obstetric Brachial Plexus Injury
Status: COMPLETED
Conditions: Erb Palsy
Interventions: OTHER: Stretch-shortening exercise|OTHER: Standard exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Polyethylene Glycol Versus Sodium Phosphate for Colon Preparation After Failure of First Preparation for Colonoscopy
Status: TERMINATED
Conditions: Colonoscopy
Interventions: DRUG: polyethylene glycol|DRUG: Sodium phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Beat to Beat A Study in Paediatric, Adolescent and Young Adult Patients Who Are Undergoing or Have Undergone Cancer Therapy to Evaluate the Agreement Between QTc Measured Using 12 Lead Electrocardiogram (ECG) and a Wearable Device ECG
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoplasms|Cardiac Arrhythmia
Interventions: DEVICE: ECG application|DEVICE: 12 lead ECG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multi-country Post-Marketing Observational Study on Maintenance of Effectiveness of Adalimumab (Humira®) in Patients With Ankylosing Spondylitis and Psoriatic Arthritis
Status: COMPLETED
Conditions: Ankylosing Spondylitis|Psoriatic Arthritis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: COVID-19 Trial of the Candidate Vaccine MVA-SARS-2-S in Adults
Status: WITHDRAWN
Conditions: Covid19
Interventions: BIOLOGICAL: MVA-SARS-2-S|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Efficacy and Safety of Ryanodex as Adjuvant Treatment in Subjects With EHS
Status: COMPLETED
Conditions: Exertional Heat Stroke
Interventions: DRUG: Ryanodex and Standard of Care|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Non-Inferiority Study of the FRESCA Mask Versus Existing CPAP Mask for Treatment of Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Sleep Apnea|OSA
Interventions: DEVICE: FRESCA mask first night|DEVICE: CPAP Mask first night
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tumour Necrosis Factor Release in Locally Advanced Breast Cancer Patients Receiving Neoadjuvant Docetaxel
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: PROCEDURE: Fine needle aspiration assessing tumour TNFa levels
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability and Pharmacokinetics of AUT00206 in Patients With Schizophrenia, and Also Explores the Effects of AUT00206 on Relevant Central Biomarkers.
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: AUT00206|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of MI Paste Plus and Resin Infiltration in White Spot Lesions Following Orthodontic Treatment
Status: RECRUITING
Conditions: White Spot Lesions|Orthodontic Appliance Complication|Caries Arrested|Smooth Surface Caries
Interventions: DEVICE: Resin infiltration|DEVICE: Casein Phosphopeptide (CPP) - Amorphous Calcium Phosphate (ACP) - Fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of RPH-104 for Resolution and Prevention of Recurring Attacks in Adult Subjects With Familial Mediterranean Fever With Resistance to or Intolerance of Colchicine
Status: RECRUITING
Conditions: Familial Mediterranean Fever|FMF
Interventions: BIOLOGICAL: RPH-104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sleep Hygiene Given to Epilepsy Patients on Seizure Frequency and Sleep Quality
Status: ACTIVE_NOT_RECRUITING
Conditions: Epilepsy
Interventions: BEHAVIORAL: Sleep Hygiene Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Test the Blood to See if a New Medicine is Likely to Provide Pain Relief Similar to a Product Already Sold in Stores
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ibuprofen|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of 4.0 mg/kg Sugammadex at 1-2 PTC in Chinese and European Subjects (Study 19.4.335)(P05775AM1)(COMPLETED)
Status: COMPLETED
Conditions: Anesthesia, General|Neuromuscular Blockade
Interventions: DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of PEER Interactive to Inform Medication Prescription for Subjects With a Primary Diagnosis of Depression
Status: SUSPENDED
Conditions: Depression
Interventions: DEVICE: PEER Interactive Report
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aerobic Exercise is Cardio-protective in Hemato-oncological Disease and New-onset Chemotherapy
Status: RECRUITING
Conditions: Cardiotoxicity|Systolic Dysfunction|Exercise, Aerobic
Interventions: BEHAVIORAL: Aerobic exercise (experimental)|BEHAVIORAL: Flexibility exercise (active comparator)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Zopiclone on Compliance With Continuous Positive Airway Pressure in Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Placebo|DRUG: Zopiclone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhanced Secondary Intention Healing vs. Standard Secondary Intention Healing in Mohs Surgical Defects on the Head and Distal Lower Extremities
Status: COMPLETED
Conditions: Wound Heal
Interventions: DEVICE: Participants in this group will receive the experimental APIS Biomaterial on the Head.|DEVICE: Participants in this group will receive the experimental APIS Biomaterial on the Lower Extremities.|OTHER: Standard Secondary Intention Healing on the Head|OTHER: Standard Secondary Intention Healing on the Lower Extremities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Oral Vorinostat in Combination With Topotecan in Patients With Chemosensitive Recurrent SCLC
Status: TERMINATED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: topotecan, vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Placulumab (CEP-37247) Administered by the Transforaminal Epidural Route for the Treatment of Patients With Lumbosacral Radicular Pain Associated With Disk Herniation
Status: COMPLETED
Conditions: Sciatica
Interventions: DRUG: CEP-37247|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of M-health Version of "What Were We Thinking" Intervention to Promote Maternal Postpartum Mental Health
Status: UNKNOWN
Conditions: Depression, Postpartum|Anxiety Disorders and Symptoms|Maternal Behavior
Interventions: BEHAVIORAL: m-health version of WWWT intervention|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of the Relative Bioavailability of Single Dose RO4917838 and the Effect of Food in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: RO4917838|DRUG: RO4917838|DRUG: RO4927838
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Cisplatin Plus Docetaxel Versus Cetuximab, Cisplatin, and Docetaxel in Metastatic Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Cetuximab|DRUG: Cisplatin|DRUG: Docetaxel|DRUG: Capecitabine|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enthesis Differences in Rheumatoid Arthritis and Axial Spondyloarthropathy
Status: COMPLETED
Conditions: Axial Spondyloarthritis|Rheumatoid Arthritis|Enthesitis|Enthesopathy
Interventions: OTHER: ULTRASOUND
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Histologic Comparison of Healing After Tooth Extraction With Ridge Preservation Using Two Different Xenografts
Status: COMPLETED
Conditions: Partial Edentulism
Interventions: DEVICE: Bio-Oss®|DEVICE: Salvin-Oss®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Cariprazine on Cardiac Repolarization in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Cariprazine|DRUG: Risperidone/Moxifloxacin|DRUG: Risperidone/Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving the Diabetic Health of Black Men: MANUP Feasibility Trial
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Coping Behavior|Self Efficacy|Masculinity
Interventions: BEHAVIORAL: MANUP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Improving Outcomes in Cancer Patients on Oral Anti-Cancer Medications Using a Multi-modal Mobile Health Intervention
Status: COMPLETED
Conditions: Renal Cell Cancer|Prostate Cancer|Effects of Chemotherapy
Interventions: OTHER: CORA- Device:smartphones"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of Antibodies and Inflammatory Markers in Postural Tachycardia Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Postural Orthostatic Tachycardia Syndrome
Interventions: OTHER: History|OTHER: Physical|OTHER: blood draw|BEHAVIORAL: Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Statins for the Treatment of NASH
Status: RECRUITING
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liver Directed RT + Chemo-immunotherapy for ES-SCLC
Status: RECRUITING
Conditions: Small-cell Lung Cancer
Interventions: DRUG: Carboplatin|DRUG: Etoposide|DRUG: Atezolizumab|RADIATION: Stereotactic Body Radiation Therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test Whether BI 1358894 Reduces Druginduced Panic Symptoms
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1358894|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Manage Emotions to Reduce Aggression (MERA)
Status: RECRUITING
Conditions: Stress Disorders, Post-Traumatic|Aggression|Emotion Regulation
Interventions: BEHAVIORAL: Manage Emotions to Reduce Aggression|BEHAVIORAL: Present Centered Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety of rAd-IFN Administered With Celecoxib & Gemcitabine in Patients With Malignant Pleural Mesothelioma
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Pleural Mesothelioma
Interventions: BIOLOGICAL: rAd-IFN|DRUG: Celecoxib Oral Product|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 6 Month Follow up Study on the Changes of Postural Stability in Parkinsonian Patients in Response to High Frequency TMS.
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: High Frequency Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of VTS-270 in Pediatric Participants With Niemann-Pick Type C (NPC) Disease
Status: WITHDRAWN
Conditions: Niemann-Pick Disease, Type C
Interventions: DRUG: VTS-270
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suspension Syndrome
Status: COMPLETED
Conditions: Circulatory Collapse|Circulatory Failure|Syncope, Vasovagal, Neurally-Mediated|Orthostatic Hypotension
Interventions: OTHER: Suspension in a harness|OTHER: Climbing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Magnesium Supplementation in People With XMEN Syndrome
Status: COMPLETED
Conditions: XMEN
Interventions: DIETARY_SUPPLEMENT: Magnesium L-threonate|OTHER: Placebo|DRUG: Intravenous (IV) magnesium sulfate (MgSO4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Endoscopically Resected High-risk Mucosal and Low- and High-risk Submucosal Adenocarcinoma Arising in Barrett's Esophagus
Status: UNKNOWN
Conditions: Barrett Esophagus|Adenocarcinoma Esophagus|Submucosal Esophageal Adenocarcinoma|High-risk Mucosal Esophageal Adenocarcinoma
Interventions: PROCEDURE: diagnostic endoscopic resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Human Umbilical Cord Blood Infusion in Patients With Acute Ischemic Stroke (AIS)
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: BIOLOGICAL: hUCB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Tolerability and Efficacy of Anacetrapib in Patients With Coronary Heart Disease (CHD) or CHD Risk-Equivalent Disease (MK-0859-019)
Status: COMPLETED
Conditions: Coronary Heart Disease (CHD)|CHD Risk-Equivalent Disease
Interventions: DRUG: anacetrapib|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Pelvic Hypofractionated Radiation Followed by Brachytherapy for Cervical Cancer
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: RADIATION: Hypofractionated therapy|RADIATION: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Peripheral Stem Cell Transplantation in Treating Patients With Stage IV Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: fludarabine phosphate|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulation of Gut Microbiota to Enhance Health and Immunity
Status: ACTIVE_NOT_RECRUITING
Conditions: Gut Microbiota|COVID-19 Vaccine
Interventions: DIETARY_SUPPLEMENT: Microbiome immunity formula|DIETARY_SUPPLEMENT: Active placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Less Bleeding by Omitting Aspirin in Non-ST-segment Elevation Acute Coronary Syndrome Patients
Status: RECRUITING
Conditions: Non ST Segment Elevation Acute Coronary Syndrome
Interventions: DRUG: No aspirin|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RESIST : Administration of MAP4343 in Antidepressant Non-Responders Patients Experiencing a Major Depressive Episode
Status: RECRUITING
Conditions: Depression
Interventions: DRUG: MAP4343|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Functioning in Persons With Chronic Pain Post-SCI Through Virtual Classroom Education
Status: COMPLETED
Conditions: Chronic Pain|Spinal Cord Injuries
Interventions: OTHER: Education Program Type 1|OTHER: Education Program Type 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Baby's First Bites: Promoting Vegetable Intake in Infants and Toddlers
Status: COMPLETED
Conditions: Vegetable Acceptance in Early Childhood|Childhood Obesity|Childhood Overweight
Interventions: OTHER: Vegetable exposure|BEHAVIORAL: VIPP-Feeding Infants|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Support for Adolescents With Celiac Disease
Status: COMPLETED
Conditions: Celiac Disease in Children
Interventions: BEHAVIORAL: Celiac Disease Definition, Symptoms and Treatment|BEHAVIORAL: Difficulties Due to Celiac Disease|BEHAVIORAL: Gluten Free Diet in Celiac Disease|BEHAVIORAL: Difficulties Related to Disease in School and Social Life|BEHAVIORAL: Celiac Disease and Its Effects on Acamdemic Success Peer Relations|BEHAVIORAL: Celiac Diseae anf Future Goals|OTHER: No Intervention: routine health care- control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Study of ORG 25935 Modulation of Ketamine-induced Behavioral and Cognitive Effects in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ketamine and Org 25935|DRUG: Placebo and Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial to Evaluate Efficacy+Safety of Revita DMR Treatment Paradigm 1 and Retreatment in Type 2 Diabetes Patients
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: Revita® DMR Treatment|OTHER: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Covered Versus Uncovered Self-expandable Metallic Stents for Malignant Gastric Outlet Obstruction
Status: COMPLETED
Conditions: Gastric Outlet Obstruction Due to Gastric Adenocarcinoma
Interventions: DEVICE: Covered stent (Bona stent pyloric/duodenal covered) insertion|DEVICE: Uncovered stent (Bona stent, pyloric/duodenal) insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Microinvasive Pars Plana Vitrectomy Combined ILM Peeling Versus Anti-VEGF Intravitreal Injection for Treatment-naïve Diabetic Macular Edema
Status: RECRUITING
Conditions: Diabetic Macular Edema|Pars Plana Vitrectomy|Conbercept
Interventions: PROCEDURE: Vitrectomy combined with ILM peeling|DRUG: Conbercept intravitreal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIIT vs HRV-based Training for Rehabilitation After Stroke
Status: RECRUITING
Conditions: Stroke|Cardiac Disease|Ischemic Stroke|Ischemic Heart Disease|Stroke, Ischemic
Interventions: OTHER: HIIT|OTHER: HRV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Food Study of Divalproex Sodium Extended-Release Tablets 500 mg to Depakote ER® Tablets 500 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Divalproex Sodium Extended-Release Tablets 500 mg|DRUG: Depakote ER® Tablets 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Intracoronary of Nicorandil and Verapamil to Reduce the Occurrence of Periprocedural Myocardial Injury
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Nicorandil|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Inflammatory Response Following " Pulsed Field Ablation " vs. Radiofrequency Ablation-2
Status: RECRUITING
Conditions: Atrial Fibrillation|Catheter Ablation|Inflammation
Interventions: DEVICE: Radiofrequency|DEVICE: Pulsed electric field
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Folic Acid vs 5-methyltetrahydrofolate (5MTHF) in Recurrent Abortion
Status: COMPLETED
Conditions: Recurrent Abortion
Interventions: DIETARY_SUPPLEMENT: 5-methyltetrahydrofolate|DIETARY_SUPPLEMENT: folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Midazolam When Co-administered With HEC74647 and HEC110114
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Midazolam Syrup|DRUG: HEC74647PA|DRUG: HEC110114
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating Superion™ In Spinal Stenosis
Status: COMPLETED
Conditions: Lumbar Spinal Stenosis|Intermittent Claudication
Interventions: DEVICE: Superion™ Interspinous Spacer|DEVICE: X-STOP® IPD® Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel, Cisplatin, and Radiation Therapy With or Without Cetuximab in Treating Patients With Locally Advanced Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: cetuximab|DRUG: cisplatin|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PMCF Retrospective Study Outcomes of a Premium Monofocal IOL
Status: COMPLETED
Conditions: Cataract|Lens Opacities
Interventions: DEVICE: IOL implantation experimental (Isopure 1.2.3.)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasal Desmopressin Versus Topical Epinephrine in Endonasal Dacryocystorhinostomy
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Desmopressin Acetate Nasal, 10 μg/0.1 ml per spray|DRUG: Epinephrine topical 1:100,000 Nasal Packs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Colecalciferol as an Add-on Treatment to Interferon-beta-1b for Treatment of Multiple Sclerosis (MS)
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: DRUG: Colecalciferol|DRUG: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Total Daily Doses of Polyethylene Glycol (PEG) 400 Administered Orally to Healthy Male Human Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PEG 400|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: EVALUATION OF BONE PARAMETERS IN PATIENTS WITH PATELLO-FEMORAL DISORDERS
Status: COMPLETED
Conditions: Patello Femoral Syndrome
Interventions: DIAGNOSTIC_TEST: "Cone Beam Computed Tomography" (CBCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intensity of Aerobic Training and Neuroprotection in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson's Disease
Interventions: BEHAVIORAL: High Intensity Aerobic program|OTHER: Conventional Physical Therapy|BEHAVIORAL: Medium Intensity Aerobic program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cold Challenge With C21 in RP
Status: COMPLETED
Conditions: Raynaud Phenomenon|Systemic Sclerosis
Interventions: DRUG: C21|DRUG: C21|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin Effect in Cognitive Impairment in Stroke Trial
Status: RECRUITING
Conditions: Stroke, Ischemic|Mild Cognitive Impairment|Dementia, Vascular|Metabolic Syndrome
Interventions: DRUG: Dapagliflozin 10mg Tab|DRUG: Statins (Cardiovascular Agents)|DRUG: Platelet Antiaggregant|DRUG: Antidiabetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Endomicrocancer: Confocal Endomicroscopy in Patients With High Risk of Colorectal Cancer
Status: TERMINATED
Conditions: Inflammatory Bowel Disease (IBD)|Familial Adenomatous Polyposis
Interventions: DEVICE: Confocal endomicroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cognitive Behavioural Therapy for the Treatment of Late Life Depression
Status: COMPLETED
Conditions: Late-life Depression|Major Depressive Disorder|Major Depressive Episode|Major Depressive Disorder, Recurrent
Interventions: BEHAVIORAL: Psychotherapy|DIAGNOSTIC_TEST: Questionnaires|OTHER: Magnetic Resonance Imaging|OTHER: Blood analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Vs Robotic-Assisted Radical Cystectomy: A Randomized Trial
Status: COMPLETED
Conditions: Bladder Cancer Requiring Cystectomy
Interventions: PROCEDURE: Open radical cystectomy|PROCEDURE: Robotic assisted radical cystectomy|DEVICE: DaVinci robot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Local Anesthetic EMLA (Lidocaine 2.5% and Prilocaine 2.5%) Cream and Reduction in Dose, Pain and Intravenous Analgesic During Permanent Pacemaker Implantation
Status: UNKNOWN
Conditions: Pacemaker Implantation|Pain
Interventions: DRUG: EMLA Analgesic Cream|DRUG: Dormicum 2.5 mg and Pethidine 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Changes on Pain and Range of Motion by the Use of Kinesio Taping in Patients Diagnosed With Cervical Pain
Status: COMPLETED
Conditions: Mobility Limitation|Myofascial Trigger Point Pain
Interventions: DEVICE: Kinesio Taping|DEVICE: Sham Kinesio Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interleukin-1 Receptor Antagonist and Insulin Sensitivity
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Insulin Resistance
Interventions: DRUG: Anakinra (Kineret)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-CD137 and Anti-CTLA-4 Monoclonal Antibody in Patients With Advanced Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Cancer
Interventions: DRUG: AGEN2373|DRUG: Botensilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Dose Escalation Study With an Allosteric AKT 1/2 Inhibitor in Patients
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: BAY1125976|DRUG: BAY1125976|DRUG: BAY1125976
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT: Oral Appliance Therapy and Sleep Position Trainer in Patients With Position Dependant Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Sleep Position Trainer|Oral Appliance Therapy
Interventions: DEVICE: sleep position trainer|DEVICE: Oral Appliance Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MYocardial DAmage AND MIcrobiota STUDY
Status: UNKNOWN
Conditions: Chronic Stable Angina|Periprocedural Myocardial Damage
Interventions: DIETARY_SUPPLEMENT: Probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Controlled Crossover Comparison of Icon Underwear to Disposable Pads
Status: COMPLETED
Conditions: Reusable Underwear, Urinary Incontinence, Dispoable Pad
Interventions: DEVICE: Icon resuable underwear|DEVICE: Disposable pad
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Sedation During Transesophageal Echocardiography on Heart Rate Variability
Status: COMPLETED
Conditions: Transesophageal Echocardiography
Interventions: DRUG: local anesthesia|BEHAVIORAL: hypnosis|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre- and Postoperative Cardiopulmonary Rehabilitation Reduces Complications After Coronary Artery Bypass Surgery: A Randomized Trial
Status: COMPLETED
Conditions: Coronary Artery Bypass Surgery
Interventions: BEHAVIORAL: REHAB (Pre- and postoperative cardiopulmonary rehabilitation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of C-CAR039 Treatment in Subjects With r/r NHL Subjects Non-Hodgkin's Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Hodgkin's B-cell Lymphoma
Interventions: BIOLOGICAL: Prizloncabtagene Autoleucel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Patients With High C-reactive Protein After Scheduled Resection of Colorectal Cancer
Status: COMPLETED
Conditions: Colon and/or Rectal Resection With Anastomosis for Cancer
Interventions: PROCEDURE: blood sample|RADIATION: CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Assess the Safety and Tolerability of the Tor Kinase Inhibitor AZD8055
Status: COMPLETED
Conditions: Cancer|Solid Tumors|Advanced Solid Malignancies
Interventions: DRUG: AZD8055
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pursuing Reduction in Fatigue After COVID-19 Via Exercise and Rehabilitation (PREFACER): A Randomized Feasibility Trial
Status: NOT_YET_RECRUITING
Conditions: Long-COVID|Long COVID-19|Post-COVID-19 Syndrome|Post-COVID Syndrome|Fatigue|Post COVID-19 Condition|Post-COVID Condition
Interventions: OTHER: COVIDEx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Efficiency of Radial Extracorporeal Shock Wave Therapy at Different Pulses in Carpal Tunnel Syndrome
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: extracorporeal shockwave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Clinical Observation of CO2 Fractional Laser in Female Vaginal Repair
Status: COMPLETED
Conditions: Vaginal Atrophy
Interventions: DEVICE: CO2 fractional laser（ACUPULSE,Lumenis）
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Patients With Kidney Cancer or Cancer of the Urothelium and in Healthy Participants
Status: COMPLETED
Conditions: Bladder Cancer|Kidney Cancer|Transitional Cell Cancer of the Renal Pelvis and Ureter|Urethral Cancer
Interventions: OTHER: immunologic technique|OTHER: laboratory biomarker analysis|OTHER: mass spectrometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact of Hyaluronic Acid Injections on Osteoarthritic Knee Mechanics
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Hyaluronic acid|DEVICE: Placebo (Saline injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Stereotactic Body Radiotherapy in the Treatment of Hypertrophic Obstructive Cardiomyopathy
Status: RECRUITING
Conditions: Hypertrophic Obstructive Cardiomyopathy|Stereotactic Body Radiotherapy
Interventions: RADIATION: Stereotactic Body Radiotherapy (SBRT) Treatment|OTHER: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Management of Patients With HF by Using Educational or Educational & Telephone or Telephone Interventions and Support in Cyprus
Status: UNKNOWN
Conditions: Heart Failure
Interventions: OTHER: In person education on heart failure topics before discharge|OTHER: Telephone support and education post-discharge|OTHER: Pre-discharge in person education and post-discharge telephone education and support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cold Snare Polypectomy for Small Bowel Polyps in Patients With Peutz-Jeghers Syndrome
Status: NOT_YET_RECRUITING
Conditions: Peutz-Jeghers Syndrome|Small Bowel Polyp
Interventions: PROCEDURE: Cold snare polypectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Analgesic Efficacy of US Guided ESP Block With Port Site Infiltration Following Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Erector spinae plane block|PROCEDURE: Port site infiltration|DEVICE: Ultrasound machine (Mindray DP 9900 plus; Mindray Bio-Medical Electronics, Shenzhen, China)|DRUG: Bupivacaine 0.5%|DRUG: Lidocaine 2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Brequinar Combined With Dipyridamole in Patients With Mild to Moderate COVID-19
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: Brequinar Sodium|DRUG: Dipyridamole 75 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and MORAb-028 Dose Determination Study in Subjects With Metastatic Melanoma
Status: TERMINATED
Conditions: Metastatic Melanoma|Malignant Metastatic Melanoma|Advanced Melanoma|Melanoma
Interventions: DRUG: MORAb-028
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Laparoscopy-Assisted Distal Gastrectomy and Open Distal Gastrectomy for Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Stomach Neoplasm
Interventions: PROCEDURE: laparoscopy-assisted distal gastrectomy|PROCEDURE: open distal gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: AAB-001 (Bapineuzumab) Open-Label, Long-Term Extension Study in Patients With Mild to Moderate Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: Bapineuzumab (AAB-001)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Data Analysis of Adult and Pediatric Participants With Acid Sphingomyelinase Deficiency (ASMD) on Early Access to Olipudase Alfa in France
Status: RECRUITING
Conditions: Acid Sphingomyelinase Deficiency (ASMD)
Interventions: DRUG: Olipudase alfa
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Medications for Chronic HIV: Education and Collaboration
Status: COMPLETED
Conditions: HIV Infections|Acquired Immunodeficiency Syndrome|Medication Adherence
Interventions: BEHAVIORAL: MedCHEC Tablet Computer & Adherence Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Left Uterine Displacement on Parturient Cardiovascular System
Status: COMPLETED
Conditions: Cardiac Output
Interventions: PROCEDURE: electric cardiometry|PROCEDURE: IV line insertion|PROCEDURE: spinal anesthesia ( subarachnoid block )|PROCEDURE: electric cardiometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diet, Exercise, Niacin, and Fenofibrate to Reduce Heart Disease Risk Factors in Individuals With HIV Lipodystrophy or Dyslipidemia
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|HIV Infections|Hyperlipidemia|Hypertriglyceridemia|Insulin Resistance|Atherosclerosis
Interventions: BEHAVIORAL: Diet|BEHAVIORAL: Exercise|DRUG: Niacin|DRUG: Fenofibrate|OTHER: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Insulin Glulisine, Insulin Lispro and Insulin Glargine in Type 1 or 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Insulin Glulisine|DRUG: Lispro|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Randomized, 2-Period, Crossover, Pharmacokinetics Study
Status: COMPLETED
Conditions: Pregnancy Prevention
Interventions: DRUG: LSP-5415 (etonogestrel/ethinyl estradiol vaginal ring)|DRUG: NuvaRing Vaginal Ring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Exendin-(9-39) on Fasting Adaptation and Protein Sensitivity
Status: COMPLETED
Conditions: Congenital Hyperinsulinism
Interventions: DRUG: Exendin-(9-39)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi Sensory Stimulation And Priming (MuSSAP) in Infants at Risk of Unilateral Cerebral Palsy
Status: COMPLETED
Conditions: Unilateral Cerebral Palsy
Interventions: BEHAVIORAL: Multi Sensory Stimulation and Priming|BEHAVIORAL: Intensive Usual Care (Upper Limb)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT