pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Ozurdex With Rescue Lucentis for Treating Macular Edema Secondary to Retinal Vein Occlusion
Status: UNKNOWN
Conditions: Retinal Vein Occlusion
Interventions: DRUG: Dexamethasone intravitreal implant|DRUG: Monthly Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tecemotide Following Concurrent Chemo-radiotherapy for Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Tecemotide|DRUG: Placebo|DRUG: Cyclophosphamide (CPA)|DRUG: Saline (sodium chloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Finasteride and Tamsulosin for Treatment of Benign Prostatic Hyperplasia (BPH) (MK-0906A-149 AM2)
Status: TERMINATED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Finasteride|DRUG: Tamsulosin|DRUG: Finasteride-matching placebo|DRUG: Tamsulosin-matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Esophageal Clearance Times of Oral Budesonide Preparations
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: OTHER: Xanthan Gum|OTHER: Honey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Step Up for STEM and Health Careers
Status: NOT_YET_RECRUITING
Conditions: Adolescent Behavior
Interventions: BEHAVIORAL: Step Up for STEM and Health Careers ("Step Up") game|BEHAVIORAL: Educational PowerPoint Presentation on Diversity in STEM Careers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Pembrolizumab Plus Chemotherapy in Patients With Advanced Cancer (PembroPlus)
Status: TERMINATED
Conditions: Advanced Cancer|Breast Cancer|Sarcoma|Pancreatic Cancer|Small Cell Lung Cancer|Ovarian
Interventions: DRUG: Pembrolizumab|DRUG: Gemcitabine|DRUG: Docetaxel|DRUG: Nab-paclitaxel|DRUG: Vinorelbine|DRUG: Irinotecan|DRUG: Liposomal Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Accuracy of US, MRI and PET/CT in the Assessment of LNs in Cervical Cancer.
Status: RECRUITING
Conditions: Lymph Node Metastasis|Cervical Cancer
Interventions: DIAGNOSTIC_TEST: ultrasound - transvaginal/transrectal + transabdominal
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Helicobacter Pylori Eradication to Prevent Gastric Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Helicobacter Infections|Stomach Neoplasms
Interventions: DRUG: OAC triple therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Salvage Treatment With Lenalidomide and Dexamethaosne (LEN-DEX) in Patients With Relapsed/Refractory Mantle Cell Lymphoma (MCL)
Status: COMPLETED
Conditions: MANTLE CELL LYMPHOMA
Interventions: DRUG: Lenalidomide and Dexametasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TOBRADEX Ophthalmic Suspension Versus Tobramycin 0.3%/Dexamethasone 0.05% Ophthalmic Suspension
Status: COMPLETED
Conditions: Ocular Inflammation Associated With Blepharaconjunctivitis
Interventions: DRUG: Tobramycin 0.3%/Dexamethasone 0.05%|DRUG: TOBRADEX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic and Echocardiographic Assessment of Riociguat Effects on Myocardial Wall Contractility and Relaxation Kinetics
Status: TERMINATED
Conditions: Hypertension, Pulmonary|Ventricular Dysfunction, Left
Interventions: DRUG: Riociguat (Adempas, BAY63-2521)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COrticosteroid in Congenital Adrenal Hyperplasia
Status: UNKNOWN
Conditions: Congenital Adrenal Hyperplasia
Interventions: BIOLOGICAL: Hormonal balance measurements|BIOLOGICAL: metabolic balance measurements|BIOLOGICAL: bone balance measurements|BEHAVIORAL: quality of life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating the Safety and Efficacy of AMOR-1 as a Treatment for Hypocalcemia Associated With Hypoparathyroidism in Adults
Status: NOT_YET_RECRUITING
Conditions: Hypoparathyroidism
Interventions: DRUG: AMOR-1|DRUG: Crystalline Calcium Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Totalfill® and ProRoot MTA® as Pulpotomy Agent in Primary Molars
Status: COMPLETED
Conditions: Extensively Decayed Primary Molars
Interventions: DRUG: Totalfill|DRUG: MTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Hernia Sac Ligation Versus Invagination
Status: COMPLETED
Conditions: Hernia, Inguinal|Postoperative Pain|Recurrence
Interventions: PROCEDURE: Lichtenstein Mesh Hernioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical Effectiveness of Boxing Training in Individuals With Elevated Blood Pressure or Stage 1 Hypertension
Status: COMPLETED
Conditions: Elevated Blood Pressure|Hypertension
Interventions: OTHER: Boxing Training|OTHER: Control flexibility
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of First-line Lazertinib and Locally Ablative Radiotherapy in Patients With Synchronous Oligo-metastatic EGFR-mutant Non-small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Lazertinib , a combination group of SBRT|DRUG: Lazertinib single administration group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Tourniquet in Bilateral Total Knee Replacement
Status: COMPLETED
Conditions: Tourniquet and Outcome After Total Knee Replacement
Interventions: DEVICE: Tourniquet|OTHER: The leg without the tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anesthesiological Strategies in Elective Craniotomy
Status: COMPLETED
Conditions: Anesthesia|Craniotomy|Neurosurgery
Interventions: DRUG: Sevoflurane + Fentanyl|DRUG: Sevoflurane + Remifentanyl|DRUG: Propofol + Remifentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Mycophenolate Mofetil and Cyclosporin, Without Concomitant Corticosteroids, After a First Renal Transplant
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: DRUG: Cyclosporin, mycophenolate mofetil, antilymphocyte serum and corticoids.|DRUG: Cyclosporin, mycophenolate mofetil, antilymphocyte serum without corticoids.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osteolysis Development Around Uncemented Cups With or Without Screw Holes
Status: COMPLETED
Conditions: Arthroplasty Complications
Interventions: DEVICE: Uncemented acetabular cup with screw holes|DEVICE: Uncemented acetabular cup without screw holes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UARK 98-026 TT II: Multiple Myeloma Evaluating Anti-Angiogenesis With Thalidomide and Post-Transplant Consolidation Chemotherapy
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Thalidomide|DRUG: Ara-C|DRUG: BCNU|DRUG: Cisplatin|DRUG: Cytoxan|DRUG: Dexamethasone|DRUG: Doxorubicin|DRUG: Etoposide|DRUG: Filgrastim|DRUG: Recombinant GM-CSF|DRUG: Interferon-alpha-2b|DRUG: Melphalan|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Personalized Biomonitoring and Report-back Intervention to Reduce Exposure to Endocrine Disrupting Chemicals
Status: RECRUITING
Conditions: Environmental Exposure
Interventions: DIAGNOSTIC_TEST: Urinary EDC metabolite testing|BEHAVIORAL: Educational curriculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Double Blind Randomized Clinical Trial of Use of Colchicine Added to Standard Treatment in Hospitalized With Covid-19
Status: UNKNOWN
Conditions: COVID-19 Infection
Interventions: DRUG: Colchcine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prolotherapy for the Treatment of Plantar Fasciitis
Status: UNKNOWN
Conditions: Plantar Fasciitis
Interventions: PROCEDURE: Regenerative injection therapy|PROCEDURE: Dry needle injection|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Neurophysiologically Based Occupational Therapy Intervention (NBOTI) for Feeding in the NCCU.
Status: COMPLETED
Conditions: Cerebral Palsy|Sensorimotor Deficits|Sensory Processing Disorder|Feeding Problems|Developmental Coordination Disorder|Picky Eaters|NICU
Interventions: OTHER: The intervention group: Neurophysiologically Based Occupational Therapy Intervention (NBOTI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TDCS Combined With CT In Opioid Use Disorder
Status: COMPLETED
Conditions: Opioid Use Disorder
Interventions: DEVICE: transcranial Direct Current Stimulation|PROCEDURE: Cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Immunogenicity of a Plant-Derived Quadrivalent Virus-Like Particles (VLPs) Influenza Vaccine in Adults
Status: COMPLETED
Conditions: Virus Diseases|RNA Virus Infections|Respiratory Tract Diseases|Respiratory Tract Infections|Influenza
Interventions: BIOLOGICAL: Quadrivalent VLP Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Cervical Treatment in Wind Musicians With Temporomandibular Dysfunction
Status: COMPLETED
Conditions: Temporomandibular Joint Dysfunction Syndrome
Interventions: OTHER: Manual therapy|OTHER: Postural exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Underlying Mechanisms of Sphenopalatine Ganglion Acupuncture for Perennial Allergic Rhinitis
Status: UNKNOWN
Conditions: Perennial Allergic Rhinitis
Interventions: PROCEDURE: SPA acupuncture|PROCEDURE: sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Effect of Eupatilin and Rebamipide on the Prevention of Gastroenteropathy
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Osteoarthritis|Ankylosing Spondylitis|Other Musculoskeletal Disorder|Gastric Ulcer|Enteritis|NSAID-Associated Gastropathy|NSAID (Non-Steroidal Anti-Inflammatory Drug) Induced Enteropathy
Interventions: DRUG: Eupatilin|DRUG: Rebamipide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Interaction in Chronic Obstructive Pulmonary Disease Experiment
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Cardiovascular Disease|Smoking|Bronchodilation
Interventions: DRUG: Tiotropium (Spiriva) + Salbutamol (Ventolin)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Quadrivalent Influenza VLP Vaccine Dose Ranging Study in Young Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Quadrivalent VLP Vaccine|BIOLOGICAL: Comparator TIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lantus Versus Humalog Mix as add-on Therapy in Type Diabetes Patients Failing Sulfonylurea and Metformin Combination Treatment
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin glargine|DRUG: 75% insulin lispro protamine suspension and 25 % insulin lispro injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Sorafenib in Treating Patients With Unresectable Stage III or Stage IV Malignant Melanoma
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage III Skin Melanoma|Stage IV Skin Melanoma
Interventions: BIOLOGICAL: Bevacizumab|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Sorafenib Tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: VX-659|DRUG: TEZ/IVA|DRUG: IVA|DRUG: Placebo (matched to VX-659/TEZ/IVA)|DRUG: TEZ|DRUG: VX-561|DRUG: Placebo (matched to VX-659/TEZ/VX-561)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Boceprevir (SCH 503034) Plus Peg-Intron, With and Without Added Ribavirin, in Patients With Chronic Hepatitis C, Genotype 1, Who Did Not Respond to Previous Treatment With Peginterferon Alfa Plus Ribavirin (Study P03659AM2)(COMPLETED)
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Boceprevir (BOC)|BIOLOGICAL: PegIntron (PEG)|DRUG: Ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Different Training Techniques in Teaching the Management of Shoulder Dystocia
Status: COMPLETED
Conditions: Shoulder Dystocia
Interventions: OTHER: Demostration|OTHER: Telesimulation|OTHER: Kahoot Game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Thrust Technique of Tibiotarsal Joint on the Symptomatology of Pain at Classical Ballet Dancers
Status: COMPLETED
Conditions: Pain|Osteopathia|Ankle Injuries
Interventions: OTHER: Tibiotarsal Thrust Manipulation|OTHER: Simulation Tibiotarsal Thrust Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-center Study to Evaluate the Safety, Tolerability and Efficacy of TIN816 in Patients at Risk for Acute Kidney Injury Following Cardiac Surgery.
Status: RECRUITING
Conditions: Acute Kidney Injury Following Cardiac Surgery
Interventions: DRUG: TIN816|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hormone Therapy Plus Chemotherapy as Initial Treatment for Local Failures or Advanced Prostate Cancer
Status: TERMINATED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Doxorubicin|DRUG: Ketoconazole|DRUG: Docetaxel|DRUG: Estramustine|DRUG: Degarelix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the CIRCULATE Catheter for Transcoronary Administration of Pharmacologic and Cell-based Agents
Status: UNKNOWN
Conditions: Dilated Cardiomyopathy
Interventions: DEVICE: Transcoronary delivery of a pharmacological agent (nitroglycerin) and cell based agent (Cardiocell) using the CIRCULATE Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: The Effect of Lying Position on Hemodynamic Parameters in Patients With Mechanical Ventilated and Spontaneously Breathing.
Status: COMPLETED
Conditions: Position Sense Disorders|Hemodynamic Instability
Interventions: OTHER: lying positions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Central Versus Peripheral Air Injection for DALK (Deep Anterior Lamellar Keratoplasty)
Status: COMPLETED
Conditions: Keratoconus
Interventions: PROCEDURE: Central air injection|PROCEDURE: Peripheral air injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Promoting Resilience in Youth Through Mindfulness mEditation
Status: RECRUITING
Conditions: Internalizing Problems
Interventions: BEHAVIORAL: Learning to Offset Stress (LOS) (in Dutch: Leren Omgaan met Stress) training|BEHAVIORAL: Care as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Accelerometer Triggered Functional Electrical Stimulation on Post-Stroke Hemiplegic Shoulder Subluxation
Status: COMPLETED
Conditions: Post-Stroke Hemiplegic Shoulder Subluxation
Interventions: PROCEDURE: Functional Electrical Stimulation (FES) treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimising Metabolic Management for People With Human Immunodeficiency Virus (HIV) on Integrase Based Antiretroviral Therapy (ART)
Status: NOT_YET_RECRUITING
Conditions: HIV Infections|Weight Gain
Interventions: DRUG: Dapagliflozin 10mg Tab|DRUG: Pitavastatin 4 Mg Oral Tablet|DRUG: Rosuvastatin and Ezetimibe|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Diode Laser as an Adjunct to Non-surgical Periodontal Treatment on Periodontal Status in Patients With Stage III-IV Periodontitis
Status: UNKNOWN
Conditions: Periodontal Diseases
Interventions: PROCEDURE: Diode laser (device) with scaling and root planing|PROCEDURE: Conventional scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of a Smartphone Mobile Application (App) to Enhance Smoking Cessation Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression|Tobacco Use Disorder|Current Every Day Smoker
Interventions: OTHER: Internet-Based Intervention|OTHER: Internet-Based Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PCI vs. CABG in the Treatment of Unprotected Left Main Stenosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Percutaneous coronary intervention|PROCEDURE: Coronary artery bypass graft operation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Interactive Preventive Health Record to Increase Colorectal Cancer Screening
Status: COMPLETED
Conditions: Colorectal Cancer Screening
Interventions: BEHAVIORAL: MyCRCS+Prefs|BEHAVIORAL: MyCRCS+Prefs+Barriers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Re-Energize Fontan
Status: RECRUITING
Conditions: Single-ventricle
Interventions: OTHER: Live-Video-Supervised Exercise Intervention|OTHER: Usual Care then Live-Video Supervised Exercise Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Targeting Pulsatile Load to Increase Exercise Capacity and Quality of Life After Aortic Valve Replacement for Severe Aortic Stenosis (PULSE AS)
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DRUG: Potassium Nitrate|DRUG: Potassium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Protection Against Influenza and COVID-19 for Pregnant Women and Medically at Risk Children
Status: RECRUITING
Conditions: Influenza|COVID-19
Interventions: BEHAVIORAL: Nudge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Multicenter, Open-Label Continuation Trial Evaluating the Tolerability and Activity of Depsipeptide (FK228) in Patients That Have Completed a Prior Clinical Study With Depsipeptide.
Status: UNKNOWN
Conditions: Peripheral T Cell Lymphoma (PTCL)
Interventions: DRUG: Depsipeptide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CPX-351 and Gemtuzumab Ozogamicin in Treating Patients With Relapsed Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: Gemtuzumab Ozogamicin|DRUG: Liposome-encapsulated Daunorubicin-Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MORDOR II Burkina Faso: Longitudinal Trial
Status: COMPLETED
Conditions: Child Growth|Diversity of Microbiome|Child Mortality|Resistance Bacterial
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Preoperative Cognitive Screening of Surgical Patients 65 Years of Age or Older
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: OTHER: Patient Survey|OTHER: Mini Cog|OTHER: Independent Activities of Daily Living Score Sheet|OTHER: Activities of Daily Living Score Sheet|OTHER: Geriatric Depression Scale Short Form|OTHER: Confusion Assessment Method (CAM)|OTHER: RAND 36-Item Short Form Health Survey|OTHER: Grip Strength
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anti-CD38 Antibody Treating Pediatric Primary Immune Thrombocytopenia (ITP)
Status: RECRUITING
Conditions: Immune Thrombocytopenia|Treatment
Interventions: DRUG: Anti-CD38 antibody Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Program on Quality of Life and Stress in Children Undergoing Hemodialysis
Status: NOT_YET_RECRUITING
Conditions: Quality of Life
Interventions: OTHER: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: C-arm Cone Beam CT Perfusion Guided Cerebrovascular Interventions
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DIAGNOSTIC_TEST: C-Arm Cone Beam Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Evaluation of Miebo (Perfluorohexyloctane) Eyedrops in Habitual Contact Lens Wearers
Status: COMPLETED
Conditions: Dry Eye|Dry Eye, Evaporative|Dry Eye Disease|Evaporative Dry Eye|Evaporative Dry Eye Disease|Kerato Conjunctivitis Sicca
Interventions: DRUG: Miebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Pegylated rhG-CSF and rhG-CSF as Support to Breast Cancer Patients Receiving Chemotherapy
Status: COMPLETED
Conditions: Breast Cancer|Neutropenia|Febrile Neutropenia
Interventions: DRUG: Drug: Pegylated rhG-CSF: 100µg/kg|DRUG: Pegylated rhG-CSF: 6mg|DRUG: rhG-CSF 5ug/kg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Predictive Value of Geriatric Oncology Screening and Geriatric Assessment in Older Patients With Solid Cancers
Status: RECRUITING
Conditions: Frailty|Cancer|Age
Interventions: OTHER: Comprehensive Geriatric Assessment and follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of UCPVax Plus Nivolumab as Second Line Therapy in Advanced Non Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Non-small Cell Lung Cancer
Interventions: DRUG: UCPVax + Nivolumab|DRUG: standard chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Open Label Dose Escalation Study to Investigate the Safety & Pharmacokinetics of AZD5312 in Patients With Androgen Receptor Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumours With Androgen Receptor Pathway as a Potential Factor
Interventions: DRUG: AZD5312
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization and Contribution of Genome-wide DNA Methylation (DNA Methylation Episignatures) in Rare Diseases With Prenatal Onset
Status: NOT_YET_RECRUITING
Conditions: Rare Fetal Genetic Diseases|Congenital Malformation
Interventions: GENETIC: Methylation analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Evaluation Study to Identify the Effectiveness of Clinical Supervision With Regards to Work-related Strain, Sense of Coherence, Increased Cultural Sensitivity and the Impact on Patient's Care: A Prospective Longitudinal Study in Mental Health Services in Qatar
Status: COMPLETED
Conditions: Work Related Stress|Sense of Coherence|Cultural Sensitivity|Clinical Supervision
Interventions: OTHER: Clinical Supervision
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Olezarsen (ISIS 678354) Administered Subcutaneously to Participants With Severe Hypertriglyceridemia (SHTG)
Status: RECRUITING
Conditions: Severe Hypertriglyceridemia
Interventions: DRUG: Olezarsen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Flow Nasal Cannula and Conventional Oxygen Therapy in the Postoperative Management of Patients With Mild to Moderate Obstructive Sleep Apnea
Status: RECRUITING
Conditions: High Flow Nasal Cannula|Obstructive Sleep Apnea
Interventions: OTHER: High flow nasal cannula therapy group|OTHER: Conventional oxygen therapy group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Forward and Retroflexion Withdrawal in the Detection of Polyps and Adenoma During Colonoscopy
Status: COMPLETED
Conditions: Colonic Polyp|Colonic Neoplasms|Colonic Adenoma
Interventions: DIAGNOSTIC_TEST: Colonoscopy with Retroview scope combing forward and retroflexed withdrawal technique|DIAGNOSTIC_TEST: Colonoscopy with standard colonoscope and forward withdrawal technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Anti-CD19 Allo-CAR-T Cells for Relapsed B Cell Malignancies After HSCT
Status: UNKNOWN
Conditions: Relapsed Adult ALL|B Cell Leukemia
Interventions: BIOLOGICAL: anti-CD19 allo-CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Adipose Tissue Derived Mesenchymal Stem Cells for Knee Osteoarthrosis
Status: UNKNOWN
Conditions: Knee Osteoarthrosis
Interventions: BIOLOGICAL: Adipose tissue derived mesenchymal stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Low-level Laser Therapy in Orthodontic Retention for Periodontal-compromised Patients
Status: COMPLETED
Conditions: Orthodontics|Periodontal Diseases
Interventions: DEVICE: low-level laser therapy|OTHER: orthodontic retention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Triamcinolone Acetonide as an Adjunctive to VPDT in ARMD.
Status: UNKNOWN
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: EvaluatioN of HIFU Hemiablation and Short Term AndrogeN Deprivation Therapy Combination to Enhance Prostate Cancer Control.
Status: RECRUITING
Conditions: Prostate Cancer|Androgen Deprivation Therapy
Interventions: DRUG: HIFU hemi-ablation combined with ADT.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Pazopanib Versus Placebo as Maintenance Therapy for Advanced Soft Tissue Sarcoma
Status: WITHDRAWN
Conditions: Sarcoma, Soft Tissue
Interventions: DRUG: Pazopanib 800 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Raltegravir in Human Immunodeficiency Virus/Hepatitis C Virus (HIV/VHC) Coinfected Patients With Advanced (Child-Pugh C) Hepatic Cirrhosis
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|Hepatitis C
Interventions: DRUG: Raltegravir 400 mg/12hours|DRUG: Raltegravir 400 mg/12hours
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing PF-05089771 TS Capsule To PF-05089771 TS Oral Dispersion In The Fasted State
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: PF-05089771|DRUG: PF-05089771
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strengthening Inspiratory and Oropharyngeal Muscles in Moderate Obstructive Sleep Apnea Hypopnea Syndrome
Status: NOT_YET_RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: OTHER: Inspiratory and Oropharyngeal Muscle Strengthening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Repetitive TMS & Cognitive Training in Adults With Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia Spectrum and Other Psychotic Disorders|Cognitive Impairment
Interventions: DEVICE: rTMS|BEHAVIORAL: Computerized cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mobility and Physical Activity in Adolescent and Young Adult Cancer Patients or Survivors at Risk for Cardiovascular Morbidity and Frailty, The MOBILE AYA Study
Status: WITHDRAWN
Conditions: Central Nervous System Neoplasm|Hodgkin Lymphoma|Malignant Solid Neoplasm|Non-Hodgkin Lymphoma|Sarcoma
Interventions: OTHER: Smartphone Application
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intestinal Remodeling And Reprogramming of Glucose Metabolism Following Laparoscopic Roux-en-Y Gastric Bypass
Status: WITHDRAWN
Conditions: Type 2 Diabetes|Obesity
Interventions: OTHER: Mix Nutrient Meal|OTHER: labs|OTHER: Biopsy|OTHER: Second Mix Nutrient Meal|OTHER: Second biopsy|DEVICE: PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Radiation and Androgen Ablation for Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Adenocarcinoma of the Prostate
Interventions: RADIATION: Radiation Therapy|DRUG: Androgen Deprivation Therapy (ADT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Mulligan Mobilization Technique and Mckenzie Exercises Among Patient With Sacroilliac Joint Dysfunction
Status: UNKNOWN
Conditions: Sacroiliac Joint Somatic Dysfunction
Interventions: DIAGNOSTIC_TEST: Mulligan Mobilization|DIAGNOSTIC_TEST: Mckenzie Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: "The Role of the Liver for Interorgan Metabolic Crosstalk in Type 2 Diabetes"
Status: ENROLLING_BY_INVITATION
Conditions: Type2 Diabetes
Interventions: DRUG: On Metformin|DRUG: Off Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acupuncture for Stiffness of Joint Related to Aromatase Inhibitors in Patients With Early-Stage Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Stiffness of Hand, Not Elsewhere Classified
Interventions: DEVICE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CSD1601: A Study to Evaluate the Exposure to Tar and Nicotine From Two Cigarette Products That Contain a Menthol Capsule in the Filter
Status: COMPLETED
Conditions: Smoking|Tobacco Smoking|Tobacco Use
Interventions: OTHER: 1601A|OTHER: 1601B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety, Efficacy Evaluation of Empagliflozin Administration for Neutropenia in Glycogenosis Type 1b and G6PC3 Deficiency
Status: UNKNOWN
Conditions: Glycogen Storage Disease Type I|Glucose 6 Phosphatase Deficiency
Interventions: DRUG: Empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pacritinib Before Transplant for Myeloproliferative Neoplasms (MPN)
Status: TERMINATED
Conditions: Myeloproliferative Diseases
Interventions: DRUG: Pacritinib|DRUG: Busulfan|BEHAVIORAL: Questionnaires|BEHAVIORAL: Phone Calls|PROCEDURE: Allogeneic Stem Cell Transplantation|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-term Follow-up Study of Participants Who Received Delandistrogene Moxeparvovec (SRP-9001) in a Previous Clinical Study
Status: ENROLLING_BY_INVITATION
Conditions: Duchenne Muscular Dystrophy
Interventions: GENETIC: delandistrogene moxeparvovec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: First in Patient Study for PF-06840003 in Malignant Gliomas
Status: TERMINATED
Conditions: Oligodendroglioma|Astrocytoma|Malignant Glioma
Interventions: DRUG: PF-06840003
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Trial of Alectinib and Bevacizumab in Patients With Advanced, Anaplastic Lymphoma Kinase (ALK)-Positive, Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Alectinib|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High "on Treatment" Platelet Reactivity in the Intensive Care Unit
Status: UNKNOWN
Conditions: Critical Illness
Interventions: DRUG: acetylsalicylic acid|DRUG: clopidogrel|DRUG: prasugrel|DRUG: ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of a Novel Amino-acid Based Hydration Drink in Healthy Volunteers
Status: COMPLETED
Conditions: Safety|Tolerance
Interventions: DIETARY_SUPPLEMENT: Crystal Light (once serving)|DIETARY_SUPPLEMENT: Liquid IV with amino acids (one serving)|DIETARY_SUPPLEMENT: Liquid IV with amino acids (two servings)|DIETARY_SUPPLEMENT: Liquid IV with amino acids (three servings)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Evaluation of Two Film-Coated Formulations of Valsartan 160 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Valsartan 160 mg film-coated caplets (test formulation)|DRUG: Valsartan 160 mg film-coated caplets (reference formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Consolidation Therapy for Acute Myeloid Leukemia Guided by Leukemia Stem Cell Behavior
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine consolidation|DRUG: Allogeneic transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemo-endocrine Therapy and Immunotherapy for Pre-menopausal Luminal B Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: Triptorelin|DRUG: Exemestane|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulating Interaction of Motor Learning Networks in Rehabilitation of Stroke
Status: COMPLETED
Conditions: Stroke|Stroke, Chronic|Stroke, Middle Cerebral Artery With Infarction
Interventions: DEVICE: Active continuous theta burst stimulation (cTBS)|DEVICE: Placebo (Sham) continuous theta burst stimulation|BEHAVIORAL: Motor Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of LY3009104 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: LY3009104|DRUG: Placebo|DRUG: moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetics of SPI-2012 (Eflapegrastim) in Breast Cancer Patients Receiving Docetaxel and Cyclophosphamide (TC) Chemotherapy
Status: COMPLETED
Conditions: Breast Cancer|Pharmacokinetics
Interventions: DRUG: SPI-2012
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluorine F 18 Clofarabine PET/CT in Imaging Patients With Autoimmune or Inflammatory Diseases
Status: COMPLETED
Conditions: Autoimmune Disease|Crohn Disease|Inflammatory Disorder|Rheumatoid Arthritis|Systemic Lupus Erythematosus|Takayasu Arteritis
Interventions: PROCEDURE: Computed Tomography|RADIATION: Fluorine F 18 Clofarabine|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Bilateral Thoracic Paravertebral Block to Thoracic Epidural Analgesia for Post Operative Analgesia in Patients Undergoing Abdominal Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Thoracic epidural analgesia|PROCEDURE: Bilateral Paravertebral block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth Factor Enhanced Matrix With Subepithelial Connective Tissue Graft or Collagen Membrane in Treatment of Gingival Recession
Status: COMPLETED
Conditions: GINGIVAL RECESSION
Interventions: PROCEDURE: GROUPI|PROCEDURE: GROUP II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia (ALL)|Acute Myeloid Leukemia (AML)|Myelodysplastic Syndromes (MDS)|NK-Cell Leukemia|Hodgkin Lymphoma|Non Hodgkin Lymphoma (NHL)|Juvenile Myelomonocytic Leukemia (JMML)|Chronic Myeloid Leukemia (CML)
Interventions: DRUG: Cyclophosphamide|BIOLOGICAL: Fludarabine|DRUG: Thiotepa|DRUG: Melphalan|BIOLOGICAL: G-csf|DRUG: Mesna|DEVICE: CliniMACS|BIOLOGICAL: ATG (rabbit)|DRUG: Blinatumomab|BIOLOGICAL: TCRα/β+|BIOLOGICAL: CD19+|BIOLOGICAL: CD45RA-depleted DLI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Non-pulsatile Blood Flow on CO2-Reactivity
Status: COMPLETED
Conditions: Cerebrovascular Circulation
Interventions: PROCEDURE: alteration of PaCO2 level
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Efficiency of Different Oropharyngeal Airways as a Conduit for Fiberoptic Intubation. Comparative Study
Status: COMPLETED
Conditions: Fiberoptic Tracheal Intubation
Interventions: DEVICE: Modified Williams airway|DEVICE: Modified Guedle's airway|DEVICE: LMA MADgic airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: The SOAR Study: a Study of Geriatric Assessment and Exercise for Older Adults and Their Support Person
Status: RECRUITING
Conditions: Lung Cancer|Gastro-intestinal Cancer|Genito-Urinary Cancer
Interventions: BEHAVIORAL: GAM, exercise, health education|BEHAVIORAL: online chair-based exercise combined with health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Evaluating The PF-03084014 In Combination With Docetaxel In Patients With Advanced Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer Metastatic
Interventions: DRUG: PF-03084014|DRUG: PF-03084014|DRUG: PF-03084014|DRUG: Docetaxel|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnesium Sulfate in Combination With Dexmedetomidine As Adjuvants to Levobupivacaine
Status: COMPLETED
Conditions: Spermatic Cord Block
Interventions: DRUG: Control Test|DRUG: Dexmedetomidine|DRUG: Dexmedetomidine and magnesium sulphate|DRUG: magnesium sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Can Low Molecular Weight Heparin During Pregnancy With Intrauterine Growth Restriction Increase Birth Weight?
Status: COMPLETED
Conditions: Fetal Growth Retardation
Interventions: DRUG: Innohep (Tinzaparin)|DRUG: tinzaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stellate Ganglionic Block Versus Stellate Ganglionic Block Plus Pecs II Block for Mastectomy Pain
Status: UNKNOWN
Conditions: Post Mastectomy Pain Syndrome|After Breast Surgery
Interventions: OTHER: Stellate ganglionic block|OTHER: Pecs II block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Resistance Training Volume on Cognitive Function and Physical Performance in Cognitively Impaired Individuals
Status: ACTIVE_NOT_RECRUITING
Conditions: Cognitive Impairment
Interventions: OTHER: Control Phase ( 6Weeks)|OTHER: 15% increase in resistance training volume (10 Weeks)|OTHER: 30% increase in resistance training volume (10 Weeks)|OTHER: One group that performed 15% more volume and increased to 30% (10 Weeks)|OTHER: One group that performed 30% more volume and increased to 45% (10 Weeks).|OTHER: Control group ( 29 Weeks)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT