pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Improvement of Anorectal Function While Preserving of Inferior Mesenteric Artery Performing Left Hemicolectomy for Diverticulosis
Status: COMPLETED
Conditions: Defecatory Disorders After Left Colonic or Rectal Resection
Interventions: PROCEDURE: Inferior Mesenteric Artery Preservation|PROCEDURE: Inferior Mesenteric Artery Ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Open-label Extension Study to Investigate Possible Drug-drug Interactions Between Clobazam and Cannabidiol
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: GWP42003-P|DRUG: Clobazam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Collaborative Requesting on DCD Refusal Rates: Randomized Controlled Trial
Status: RECRUITING
Conditions: Organ Donation|Required Organ Donation Request|Professional Family Relations|Intensive Care Units
Interventions: OTHER: Collaborative request
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Investigating a Probiotic on Mothers' Mood and Stress
Status: COMPLETED
Conditions: Perinatal Problems|Mood Change|Stress-related Problem
Interventions: OTHER: (BL) NCC3001|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Risk of Gastric Reflux During Tulip vs GMA(Glottis Mask Airway) Airway
Status: NOT_YET_RECRUITING
Conditions: Anesthesia
Interventions: DEVICE: glottis mask airway|OTHER: tulip shaped|OTHER: classical shaped
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neuromodulation of Different Doses to Treat TRD Guided by pBFS Technique
Status: RECRUITING
Conditions: Moderate Depression|Major Depressive Disorder|Severe Depression
Interventions: DEVICE: 4 session rTMS|DEVICE: 6 session rTMS|DEVICE: 8 session rTMS|DEVICE: 10 session rTMS|DEVICE: sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Hyperthermia Therapy in Treating Patients With Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: ifosfamide|PROCEDURE: conventional surgery|PROCEDURE: hyperthermia treatment|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Intestinal Microbiota Transplant in Alcohol-Associated Liver Disease
Status: RECRUITING
Conditions: Liver Disease; Alcohol-Related|Cirrhosis|Alcohol Use Disorder
Interventions: DRUG: Intestinal Microbiota Transplant (IMT) Capsules|DRUG: Placebo Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pneumoperitoneum (Raised Pressure in the Peritoneal Cavity) During Robotic Kidney/Prostate Cancer Surgery.
Status: COMPLETED
Conditions: Acute Kidney Injury|Pneumoperitoneum|Kidney
Interventions: PROCEDURE: Low intra-abdominal pressure|PROCEDURE: High (standard) intra-abdominal pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: RCT: HDWL vs Virtual Chromoendoscopy in the Detection of Intraepithelial Neoplasia in Longstanding Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis|Crohn's Colitis
Interventions: OTHER: Chromoendoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Helpfulness of the Vibration Test Performed in Room Light on Clients With Inner Ear Problems
Status: COMPLETED
Conditions: Vestibular Disease
Interventions: BEHAVIORAL: Dizziness Handicap Inventory|BEHAVIORAL: Global Rating of Change|BEHAVIORAL: Patient Acceptable Symptom State|PROCEDURE: Spontaneous Nystagmus Test|PROCEDURE: Gazehold Nystagmus Test|PROCEDURE: Primary Vibration Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Outcome Research to Confirm the Anti-anginal Effect of T89 in Patients With Stable Angina
Status: UNKNOWN
Conditions: Chronic Stable Angina Pectoris
Interventions: DRUG: T89 capsule|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Levocetirizine Plus Bed-Time Hydroxyzine in the Management of Corticodependent Chronic Urticaria Versus Levocetirizine Alone in High Doses
Status: COMPLETED
Conditions: Chronic Urticaria
Interventions: DRUG: Levocetirizine|DRUG: Levocetirizine plus Hydroxyzine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mobilization With Movement on Pain and Function Among Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: OTHER: MWM Treatment|OTHER: MWM Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: All Eyes on PCS - Analysis of the Retinal Microvasculature in Patients With Post-COVID-19 Syndrome
Status: RECRUITING
Conditions: Long Covid19|Post COVID-19 Condition|Endothelial Dysfunction
Interventions: DIAGNOSTIC_TEST: Dynamic retinal vessel analysis (DVA)|DIAGNOSTIC_TEST: Optical coherence tomography (OCT)|DIAGNOSTIC_TEST: Biochemistry and immune phenotyping|DIAGNOSTIC_TEST: Handgrip strength test|DIAGNOSTIC_TEST: Questionnaires (Patient reported outcomes)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose Individualization of Chemotherapy in Patients With Gastrointestinal Cancers Lacking a Specific Liver Enzyme
Status: NOT_YET_RECRUITING
Conditions: Digestive Cancer|Colorectal Cancer
Interventions: DRUG: FOLFOX regimen|DRUG: CAPOX regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Sintilimab and Stereotactic Body Radiotherapy in Advanced Metastatic HCC
Status: UNKNOWN
Conditions: Stage IV HCC|Immunotherapy|SBRT
Interventions: RADIATION: Stereotactic body radiation therapy|DRUG: Anti-PD-1 antibody drug named Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GPC3/Mesothelin/Claudin18.2/GUCY2C/B7-H3/PSCA/PSMA/MUC1/TGFβ/HER2/Lewis-Y/AXL/EGFR-CAR-T Cells Against Cancers
Status: RECRUITING
Conditions: Lung Cancer|Cancer|Immunotherapy|CAR-T Cell
Interventions: BIOLOGICAL: CAR-T cells targeting GPC3, Mesothelin, Claudin18.2, GUCY2C, B7-H3, PSCA, PSMA, MUC1, TGFβ, HER2, Lewis-Y, AXL, or EGFR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ketogenic Diet in Newly Diagnosed Overweight or Obese Endometrial Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Cancer
Interventions: OTHER: Ketogenic Diet (KD)|OTHER: Standard Diet (SD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dexmedetomidine on Cognitive Outcome and Brain Injury Markers
Status: COMPLETED
Conditions: Cognitive Dysfunction
Interventions: DRUG: Dexmedetomidine Infusion|DRUG: Propofol based general anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rehabilitation With Biofeedback in Neurology
Status: COMPLETED
Conditions: Rehabilitation|Biofeedback|Neurological Diseases
Interventions: OTHER: Evaluation of reliability, repeatability and validity of devices among healthy subjects|OTHER: Biofeedback method and Health-resort based rehabilitation Health-resort based treatments supplemented with biofeedback training|OTHER: Health-resort based rehabilitation Control group - health-resort based treatments, without biofeedback training.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Gemcitabine, Capecitabine and Bevacizumab to Treat Cancer of the Gall Bladder or Bile Ducts
Status: COMPLETED
Conditions: Cholangiocarcinoma
Interventions: DRUG: Gemcitabine, Capecitabine and Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gadolinium Texaphyrin Plus Radiation Therapy in Treating Patients With Supratentorial Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: motexafin gadolinium|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Nivolumab in Combination With Chemotherapy Pre-Surgery in Treating Patients With Borderline Resectable Pancreatic Cancer
Status: COMPLETED
Conditions: Borderline Resectable Pancreatic Adenocarcinoma|Resectable Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Fluorouracil|DRUG: Irinotecan|DRUG: Irinotecan Hydrochloride|DRUG: Leucovorin|DRUG: Leucovorin Calcium|BIOLOGICAL: Nivolumab|DRUG: Oxaliplatin|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Automatic Relays by Intensive Basis Advantage Compared With Manual Relays, on the Hypotension Risks, During Noradrenalin Administration
Status: COMPLETED
Conditions: Hypotension
Interventions: PROCEDURE: Measure of arterial pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: One Year Clinical Evaluation of E-max CAD Versus Cerasmart Endocrowns in Anterior Endodontically Treated Teeth
Status: UNKNOWN
Conditions: Endodontically Treated Teeth
Interventions: PROCEDURE: CERASMART Endocrown|PROCEDURE: Emax Endocrown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Clinical Trial to Determine the Feasibility of Administering an Electronic Tool to Assess Postoperative pAin, Nausea, and Vomiting in English or Spanish-Speaking Pediatric Patients With Neoplastic Conditions.
Status: RECRUITING
Conditions: Neoplastic Conditions
Interventions: OTHER: Augmented reality (AR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Steroid-Sparing Effect With Pimecrolimus in Pediatric Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Pimecrolimus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of the Inspiratory Cortical Control on the Outcome of the Ventilatory Weaning Test in Patients Intubated in Resuscitation
Status: UNKNOWN
Conditions: Respiration Disorder|Respiratory Failure|Weaning Failure|Respiratory Compensation|Respiratory Center Dysfunction
Interventions: DEVICE: Electroencephalography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prandial Orientated Biphasic Insulin Aspart 30 Therapy - the Physiological Premix Insulin Therapy for Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 30
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Allopurinol in Prevention of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis
Status: COMPLETED
Conditions: Endoscopic Retrograde Cholangiopancreatography
Interventions: DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase II Study of Dose Density Regimen With Fluorouracil, Epirubicin and Cyclophosphamide at Days 1, 4 Every 14 Days With Filgrastim Support Followed by Weekly Paclitaxel in Women With Primary Breast Cancer.
Status: COMPLETED
Conditions: Women With Primary Breast Cancer
Interventions: DRUG: FEC (Fluorouracil, Epirubicin, Cyclophosphamide) + filgrastim + paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Multi Center, Randomized, Double-blind, Positive Controlled Study of Bicyclol in the Treatment of Acute DILI
Status: COMPLETED
Conditions: Drug-Induced Acute Liver Injury
Interventions: DRUG: bicyclol tablet 25mg|DRUG: bicyclol tablet 50mg|DRUG: polyene phosphatidylcholine capsule 456mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sub-therapeutic GnRH- Antagonist Treatment to Rectify LH Pulsatility in Lean Women With PCOS.
Status: NOT_YET_RECRUITING
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Ganirelix|DRUG: Ganirelix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduction of Venous Emboli Load After Breathing Normobaric Oxygen Compared to Air
Status: COMPLETED
Conditions: Hyperbaric|Diving Medicine|Decompression Sickness|Central Nervous Injury|Inflammation|Endothelial Dysfunction
Interventions: DRUG: Oxygen|OTHER: Air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Remote Patient Monitoring on Chronic Disease Management
Status: COMPLETED
Conditions: Heart Failure|Chronic Obstructive Pulmonary Disease|Chronic Kidney Disease|Uncontrolled Hypertension|Diabetes
Interventions: DEVICE: Medly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase I, Randomized, Single-Blind, Four-Period Cross-Over, Placebo-Controlled, Dose-Escalation Study to Evaluate the Safety and Pharmacokinetics of Single Oral Doses of GR181413A/AT1001 in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Fabry Disease
Interventions: DRUG: GR181413A/AT1001 solution|DRUG: GR181413A/AT1001 capsule|OTHER: Potable water|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: A Study to Learn About a Repeat 5-Day Treatment With the Study Medicines (Called Nirmatrelvir/Ritonavir) in People 12 Years Old or Older With Return of COVID-19 Symptoms and SARS-CoV-2 Positivity After Finishing Treatment With Nirmatrelvir/Ritonavir
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: nirmatrelvir|DRUG: ritonavir|DRUG: placebo for nirmatrelvir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Restylane Volyme for Correction of Midface Volume Deficit and/or Midface Contour Deficiency
Status: COMPLETED
Conditions: Midface Volume Deficit
Interventions: DEVICE: Restylane Volyme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioresorbable Airway Splint Pivotal Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Tracheobronchomalacia
Interventions: DEVICE: Bioresorbable Tracheobronchial Splint
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine With or Without Dalteparin in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer|Thromboembolism
Interventions: DRUG: dalteparin|DRUG: gemcitabine hydrochloride|OTHER: diagnostic laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Fibrin vs Sub Epithelial Connective Tissue and Coronally Advanced Flap Alone in Gingival Recession
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: PRF+CAF treated patients|PROCEDURE: SCTG+ CAF treated patients|PROCEDURE: CAF treated patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Vagal Nerve Stimulation in Opioid Use Disorders
Status: COMPLETED
Conditions: Substance-Related Disorders|Substance Use Disorders|Substance Abuse, Intravenous|Substance Withdrawal|Substance Abuse|Opioid-use Disorder|Opioid Use Disorder, Severe|Opioid Use
Interventions: DEVICE: Non invasive VN stimulation (nVNS)|DRUG: Oxygen (15-O) Water|DEVICE: Sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Placebo Controlled Clinical Trial of the Postoperative Opioid Sparing Effects of Intraoperative Dexmedetomidine Infusion for Thoracic Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intermittent Parasite Clearance (IPC) in Schools: Impact on Malaria, Anaemia and Cognition
Status: COMPLETED
Conditions: Malaria|Anaemia
Interventions: DRUG: Intermittent parasite clearance|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nifedipine Versus Magnesium Sulfate for Prevention of Preterm Labor in Symptomatic Placenta Previa
Status: COMPLETED
Conditions: Placenta Previa
Interventions: DRUG: Magnesium Sulfate|DRUG: Nifedipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer
Status: RECRUITING
Conditions: Endometrial Cancer
Interventions: DRUG: Atezolizumab - 28 Day Cycle|DRUG: Bevacizumab|DRUG: Ipatasertib|DRUG: Talazoparib|DRUG: Trastuzumab emtansine|DRUG: Tiragolumab|DRUG: Atezolizumab - 21 Day Cycle|DRUG: Inavolisib|DRUG: Letrozole|DRUG: Giredestrant|DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Tranexamic Acid Versus Pericervical Tourniquet To Decrease Blood Loss In Trans-Abdominal Myomectomy
Status: UNKNOWN
Conditions: Post Operative Hemorrhage
Interventions: DRUG: Tranexamic Acid|PROCEDURE: Pericervical Tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Multicenter Study to Evaluate the Safety of Seasonique, an Oral Contraceptive.
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Levonorgestrel/EE 0.15/0.03 mg and EE 0.01 mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tilted Gaze Target Test in the Examination of Children With Superior Oblique Muscle Palsy
Status: NOT_YET_RECRUITING
Conditions: Children With Torticollis
Interventions: DIAGNOSTIC_TEST: Tilted Gaze Target Tast|DIAGNOSTIC_TEST: Conventional Examination Methods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Insertion of Different Supraglottic Airway Devices on Manikin
Status: COMPLETED
Conditions: Ventilation|Airway Management|Education
Interventions: DEVICE: Proseal Laryngeal Mask|DEVICE: Classic Laryngeal Mask|DEVICE: I-gel|DEVICE: Suprema Laryngeal Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Imatinib Mesylate in Treating Patients With Progressive, Refractory, or Recurrent Stage II or Stage III Testicular or Ovarian Cancer
Status: TERMINATED
Conditions: Ovarian Dysgerminoma|Recurrent Malignant Testicular Germ Cell Tumor|Recurrent Ovarian Germ Cell Tumor|Stage II Malignant Testicular Germ Cell Tumor|Stage II Ovarian Germ Cell Tumor|Stage III Malignant Testicular Germ Cell Tumor|Stage III Ovarian Germ Cell Tumor|Testicular Seminoma
Interventions: DRUG: imatinib mesylate|PROCEDURE: therapeutic conventional surgery|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DS3201 and Ipilimumab for the Treatment of Metastatic Prostate, Urothelial and Renal Cell Cancers
Status: RECRUITING
Conditions: Aggressive Variant Prostate Carcinoma|Castration-Resistant Prostate Carcinoma|Metastatic Clear Cell Renal Cell Carcinoma|Metastatic Malignant Solid Neoplasm|Metastatic Prostate Carcinoma|Metastatic Urothelial Carcinoma|Stage IV Prostate Cancer AJCC v8|Stage IV Renal Cell Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: BIOLOGICAL: Ipilimumab|DRUG: Valemetostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human Erythropoietin Compared to Autologous Pre-Donation Prior to Scoliosis Surgery in Children.
Status: COMPLETED
Conditions: Scoliosis
Interventions: PROCEDURE: rHuEpo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Transhepatic Intrahepatic Portosystemic Shunt for Treatment of Portal Vein Occlusion With Symptomatic Portal Hypertension After Splenectomy
Status: UNKNOWN
Conditions: Hypertension, Portal|Portal Vein, Cavernous Transformation Of
Interventions: PROCEDURE: Percutaneous transhepatic intrahepatic portosystemic shunt
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Vaginal Progesterone to Reduce HIV-Associated Preterm Birth
Status: COMPLETED
Conditions: PreTerm Birth
Interventions: DRUG: Vaginal Progesterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 11 To 17
Status: TERMINATED
Conditions: Down Syndrome|Cognitive Dysfunction
Interventions: DRUG: Aricept (donepezil hydrochloride)|DRUG: Aricept (donepezil hydrochloride)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Pre-operative Exercise Program for Patients With Full Thickness Rotator Cuff Tear Waiting for Surgical Repair
Status: UNKNOWN
Conditions: Rotator Cuff Tears
Interventions: OTHER: Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Pharmacokinetics, and Antitumor Activity of Oral TACH101 in Participants With Advanced or Metastatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Cancer|Metastatic Solid Tumor|Solid Tumor
Interventions: DRUG: TACH101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Central and Anterior Compartment Prolapse Surgery: A Meshless Sacrocolpopexy Technique
Status: UNKNOWN
Conditions: Prolapse Uterovaginal|Prolapse Bladder|Laparoscopy
Interventions: PROCEDURE: Laparoscopic Meshless Sacrocolpopexy Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of Efficacy of Lactobacillus CD2 Lozenges in Preventing High-Dose Chemotherapy Induced Oral Mucositis in Patients Undergoing Myeloablative Hematopoietic Stem Cell Transplantation
Status: WITHDRAWN
Conditions: Oral Mucositis in Patients Undergoing HSCT
Interventions: DRUG: Lactobacillus CD 2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dexmedetomidine Versus Sevoflurane in Children With Anticipated Difficult Intubation
Status: UNKNOWN
Conditions: Craniofacial Abnormalities|Mandibular Hypoplasia
Interventions: DRUG: dexmedetomidine|DRUG: sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Trial of a Metal on Poly Component Versus CORAIL Stem: A Bone Mineral Density Study
Status: COMPLETED
Conditions: Total Hip Arthroplasty
Interventions: DEVICE: Total hip replacement with titanium shell and CORAIL stem|DEVICE: Total hip replacement with Modular Titanium Femoral Stem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Two Doses of PF-03654746 in Adults With Attention Deficit Hyperactivity Disorder (ADHD).
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: PF-03654746|DRUG: Placebo capsules|DRUG: PF-03654746
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Almonertinib as First-line Treatment in Patients With EGFR Mutations Positive in Advanced NSCLC With Brain Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Almonertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Digital Thermal Monitoring to Assess Endothelium-Dependent Vasodilation in Patients Undergoing Hematopoietic Cell Transplantation (HCT)
Status: RECRUITING
Conditions: Vascular|Endothelial|Endothelial Dysfunction|Endothelix
Interventions: DEVICE: Vendys II Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cemented Versus Uncemented Total Knee Arthroplasty : a Prospective Randomized Study
Status: WITHDRAWN
Conditions: Total Knee Arthroplasty
Interventions: DEVICE: Surgical total knee replacement using cemented components|DEVICE: Surgical total knee replacement using uncemented components
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Side Effects and Benefits of RAS 130 With or Without Diet and Exercise in Type II Diabetes Mellitus
Status: UNKNOWN
Conditions: Type II Diabetes Mellitus
Interventions: OTHER: RAS 130 with diet and exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Ranging Study of Telintra® Tablets + Revlimid® in Patients With Non-Deletion (5q) Low to Intermediate-1 Risk Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: Ezatiostat Hydrochloride|DRUG: Lenalidomide (Revlimid®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Axillary Lymphadenectomy Without Drainage for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Complications|Seroma
Interventions: PROCEDURE: Non drains will be placed during operation|PROCEDURE: Closed suction drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryoablation Combined With Sintilimab Plus Regorafenib In Previously Treated Colorectal Cancer Liver Metastasis
Status: RECRUITING
Conditions: Liver Metastases|Colorectal Cancer Metastatic
Interventions: DRUG: Sintilimab|DRUG: Regorafenib|COMBINATION_PRODUCT: US/CT-guided Percutaneous Cryoablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Metabolic Assessments in Type 1 Diabetes Mellitus Clinical Trials
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: PROCEDURE: Mixed Meal Tolerance Test|PROCEDURE: Glucagon Stimulation Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of the Pharmacokinetics of Uprifosbuvir (MK-3682) and Ruzasvir (MK-8408) in Participants With Moderate and Severe Hepatic Insufficiency (MK-3682-029)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Uprifosbuvir|DRUG: Ruzasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Er:YAG Laser Therapy in Combination With Behaviour Management Technique in Reducing Anxiety Among Paediatric Patients
Status: UNKNOWN
Conditions: Dental Caries|Dental Anxiety|Behavior
Interventions: PROCEDURE: Laser conditioning and Sealant application|PROCEDURE: Sealant application|DEVICE: Er:YAG laser therapy|PROCEDURE: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Effects of Early Proprioceptive Stimulations in Patients With Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Proprioceptive stimulations|DEVICE: Sham stimulations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ApoGraft for the Prevention of Acute Graft Versus Host Disease in Haploidentical Hematopoietic Cell Transplant Recipients
Status: TERMINATED
Conditions: Acute Graft Versus Host Disease|Haploidentical Hematopoietic Stem Cell Transplant
Interventions: DRUG: ApoGraft
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Valve Surgery Versus Conventional Treatment in Infective Endocarditis Patients With High Risk of Embolism
Status: RECRUITING
Conditions: Endocarditis
Interventions: PROCEDURE: Early valve surgery (EVS)|PROCEDURE: Conventional Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tisleizumab Combined With Lenvatinib and XELOX Regimen (Oxaliplatin Combined With Capecitabine) in the First-line Treatment of Advanced and Unresectable Biliary Tract Tumors
Status: UNKNOWN
Conditions: Biliary Tract Tumor
Interventions: DRUG: Tislelizumab|DRUG: Lenvatinib|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Titanium Tacked Soft Tissue Stabilization : A Novel Technique For Free Gingival Graft Fixation
Status: COMPLETED
Conditions: Lack of Keratinized Gingiva
Interventions: DEVICE: titanium tacks or pins
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: The Efficacy and Safety of Intra-oral Topical Ketoprofen for the Treatment of Acute Migraine
Status: UNKNOWN
Conditions: Migraine Disorders|Migraine Headache|Migraine|Acute Migraine
Interventions: DRUG: Topical, intra-oral ketoprofen gel|OTHER: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study on the Incidence and Related Risk Factors of Infantile Hemangioma in China
Status: UNKNOWN
Conditions: Infantile Hemangioma|Capillary Hemangioma|Capillary Hemangiomas|Hemangioma, Capillary Infantile|Strawberry Hemangioma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Counseling and Reminders for Regular HIV and STIs Screening
Status: COMPLETED
Conditions: HIV, Hepatitis B, Hepatitis C and Syphilis Infections
Interventions: BEHAVIORAL: Computer-assisted counseling|BEHAVIORAL: On-demand counseling|BEHAVIORAL: Standard counseling|BEHAVIORAL: Appointment + reminder|BEHAVIORAL: Reminder|BEHAVIORAL: No appointment and no reminder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Algorithmic-Based Evaluation and Treatment Approach for Robotic Gait Training
Status: UNKNOWN
Conditions: Complete Spinal Cord Injury|Incomplete Spinal Cord Injury|Acquired Brain Injury|Multiple Sclerosis
Interventions: DEVICE: ReWalk|DEVICE: EKSO|DEVICE: REX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multinational, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Investigate the Efficacy, Safety and Duration of Effect of a Single Administration of Various Doses of Cetrorelix SR in Subjects With Histologically Confirmed Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Cetrorelix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Lamotrigine on Neuropathic Facial Pain Using fMRI
Status: COMPLETED
Conditions: Facial Neuropathy
Interventions: DRUG: Lamotrigine|DRUG: Placebo (for Lamotrigine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Core Study of the Safety and Effectiveness of IDEAL IMPLANT(R) Saline-filled Breast Implants
Status: COMPLETED
Conditions: Breast Implants
Interventions: DEVICE: Saline-filled breast implant [IDEAL IMPLANT (R)]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OPTImizing Precision of Hypertension Care to Maximize Blood Pressure Control Pilot (OPTI-BP Pilot)
Status: COMPLETED
Conditions: High Blood Pressure
Interventions: OTHER: HTN PRA App|OTHER: Blood Sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dose-Finding Clinical Trial to Evaluate the Efficacy and Safety of LY03005 Extended-release Tablets in the Treatment of Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: LY03005 extended-release tablets 40 mg|DRUG: LY03005 extended-release tablets 80 mg group|DRUG: LY03005 extended-release tablets 120 mg group|DRUG: LY03005 extended-release tablets 160 mg group|DRUG: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intake of Allium Cepa L. Peel Heated Water Extract on Immunity Enhancement
Status: ACTIVE_NOT_RECRUITING
Conditions: Upper Respiratory Infection
Interventions: DIETARY_SUPPLEMENT: Allium Cepa L. Peel Heated Water Extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: SENSOR: Study to Investigate Cinacalcet Treatment in Haemodialysis Patients With Secondary Hyperparathyroidism
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism|End Stage Renal Disease
Interventions: DRUG: cinacalcet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Safety of Functional Performance Testing in Patients Undergoing Hematopoietic Cell Transplantation
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome|Hematological Malignancy|Leukemia|Lymphoma|Myeloma
Interventions: OTHER: Symptom-limited cardiopulmonary exercise test (CPET)|OTHER: Resting assessment of cardiac function by echocardiography|OTHER: Post-exercise assessment of cardiac function by echocardiography|OTHER: Pulmonary function|BEHAVIORAL: Patient-reported outcomes questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Remote Ischemic Preconditioning on Acute Kidney Injury in Patients Undergoing Heart Valve Replacement Surgery With Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Heart Valve Disease
Interventions: PROCEDURE: Automated cuff-inflator
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: General Decolonization With Octenisan® Set Before Elective Orthopedic Surgery
Status: RECRUITING
Conditions: Elective Surgery|High Risk|Prevention of Surgical Site Infections|Randomized-controlled Trial
Interventions: DRUG: Whole Body and nasal decolonization with octenidin (Octenisan Set)|BEHAVIORAL: Questionnaire for study participants immediately after the decolonization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Methotrexate-based Chemo-immunotherapy Followed by Maintenance Therapy for Patients > 65 Years With Central Nervous System (CNS)-Lymphoma
Status: UNKNOWN
Conditions: Primary Non Hodgkin Lymphoma of the Central Nervous System
Interventions: DRUG: Methotrexate|DRUG: Lomustine|DRUG: Procarbazine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Hou Gu Mi Xi in Patients With Spleen Qi Deficiency and Radical Gastrectomy for Gastric Cancer
Status: TERMINATED
Conditions: Gastric Cancer|Gastrointestinal Disease
Interventions: DIETARY_SUPPLEMENT: Hou Gu Mi Xi|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Response With NT-I7
Status: WITHDRAWN
Conditions: Breast Carcinoma|Colorectal Adenocarcinoma|Bladder Carcinoma
Interventions: BIOLOGICAL: Recombinant human IL-7-hyFc (NT-I7)|BIOLOGICAL: Vaccine sequence 1|BIOLOGICAL: Vaccine sequence 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Phenotype and Genotype of Breast Cancers During the Metastatic Process and Optimization of Therapeutic Targeting (ESOPE)
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: OTHER: biopsy or cytopuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pragmatic Collaborative Care for Cardiac Inpatients With Depression or Anxiety
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Heart Failure|Depression|Generalized Anxiety Disorder|Panic Disorder
Interventions: BEHAVIORAL: Collaborative Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Efficacy and Safety/Tolerability Profiles of Antroquinonol in Acute Myeloid Leukemia (AML) Adult Patients
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Antroquinonol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MS-553 in Patients With Relapsed or Refractory B-cell Lymphoma
Status: TERMINATED
Conditions: Relapsed or Refractory B-cell Lymphoma|Diffuse Large B-cell Lymphoma (DLBCL)|Follicular Lymphoma (FL)|Mantle Cell Lymphoma (MCL)|Chronic Lymphocytic Leukemia (CLL)|Small Lymphocytic Lymphoma (SLL)|Marginal Zone Lymphoma (MZL)
Interventions: DRUG: MS-553
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Angiotensin Receptor Blocker Combined With Calcium Antagonist Evaluation of Safety and Lowering of Systolic Blood Pressure Study
Status: WITHDRAWN
Conditions: Hypertension
Interventions: DRUG: Perindopril|DRUG: Perindopril/amlodipine|DRUG: Olmesartan/amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Self-efficacy and Relationship Through Behavior Modification by Hybrid Mode
Status: RECRUITING
Conditions: Caregivers With Toddler Receiving Early Intervention
Interventions: BEHAVIORAL: behavior modification-Atomic Habit by hybrid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Notch Signalling Pathway Inhibitor for Patients With T-cell Acute Lymphoblastic Leukemia/Lymphoma (ALL)(0752-013)
Status: TERMINATED
Conditions: Leukemia, Lymphoblastic, Acute, T-cell|Myelogenous Leukemia|Chronic Lymphocytic Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: MK0752, (Notch Inhibitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3, Multi-Center Study of Gemcitabine/Carboplatin, With or Without BSI-201, in Patients With ER-, PR-, and Her2-Negative Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: gemcitabine/carboplatin|DRUG: Iniparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CARBETOCIN VERSUS RECTAL MISOPROSTOL FOR MANAGEMENT OF THIRD STAGE OF LABOR IN WOMEN AT LOW RISK OF POSTPARTUM HEMORRHAGE
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Carbetocin|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Reliability of CarieScan PRO Compared With Digital Radiograph and ICDAS-II in Detection of Carious Lesions
Status: UNKNOWN
Conditions: Dental Caries
Interventions: DIAGNOSTIC_TEST: ICDAS II|DEVICE: CariScan Pro|RADIATION: Digital Radiograpgy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Anti-Nephropathic Effects of Chronic Intermittent Intravenous Insulin Therapy (CIIIT)
Status: COMPLETED
Conditions: Diabetic Nephropathy|Diabetic Retinopathy
Interventions: DRUG: CIIIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized Controlled Trial Comparing Traditional Methods of Neuromuscular Block Reversal to Sugammadex for Extubation in the Operating Room in ASA 4 and 4E Patients
Status: UNKNOWN
Conditions: Neuromuscular Blockade
Interventions: DRUG: Sugammadex Reversal|DRUG: Atropine/Neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zona Pellucida Bound Sperm vs. Embryologist Selected Sperm for Intracytoplasmic Sperm Injection
Status: RECRUITING
Conditions: Infertility
Interventions: OTHER: Zona Pellucida-Bound Sperm Selection for ICSI|OTHER: Routine Embryologist Selected Sperm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Feasibility of Internet Based Support (Carer eSupport) for Informal Caregivers of Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Caregivers|Head and Neck Cancer|Feasibility Study
Interventions: OTHER: Internet based support
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nutritional Support for Lactating Women and Azithromycin to Infants - Mumta Lactating Women Trial
Status: COMPLETED
Conditions: Undernutrition
Interventions: DIETARY_SUPPLEMENT: Balanced energy-protein (BEP)|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT