pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Physical Exercise on Motor Learning Acquired With Physical or Mental Practice
Status: RECRUITING
Conditions: Physical Exercise|Motor Learning
Interventions: BEHAVIORAL: Sleep Deprivation (SD)|BEHAVIORAL: Normal Night (Night)|BEHAVIORAL: Physical Exercise (HIIE)|BEHAVIORAL: Rest control|BEHAVIORAL: Motor imagery|BEHAVIORAL: Physical Practice (PP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: SENL101 Autologous T Cell Injection in Adults With Relapsed or Refractory CD7+ Hematolymphoid Malignancies
Status: UNKNOWN
Conditions: T-ALL|Lymphoma, T-Cell
Interventions: BIOLOGICAL: SENL101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HDDO-1614 Bio Equivalence Study
Status: COMPLETED
Conditions: Osteoporosis
Interventions: COMBINATION_PRODUCT: HDDO-1614|DRUG: Bazedoxifene / Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of the Effect on Clinical Outcomes Using Secure Text Messaging
Status: WITHDRAWN
Conditions: Congestive Heart Failure|Diabetes|Renal Failure|Copd
Interventions: DEVICE: Secure text messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: COVID-19 Vaccination Willingness in Older Adults Based on Self-determination Theory
Status: COMPLETED
Conditions: Old Age; Debility|Vaccine Hesitancy|Vaccine Refusal
Interventions: OTHER: Self-determination theory-based health education measures
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: C1INH Inhibitor Preoperative and Post Kidney Transplant to Prevent DGF & IRI
Status: COMPLETED
Conditions: End Stage Renal Disease|Kidney Failure|Delayed Graft Function|Ischemic Reperfusion Injury
Interventions: DRUG: C1 Esterase Inhibitor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Intestinal and Humoral Immunity of Sequential Polio Vaccination Schedules
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: bOPV (three dose)|BIOLOGICAL: bOPV (two dose)|BIOLOGICAL: IPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Safety Study to Evaluate Pazopanib Eye Drops in Healthy Volunteers
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: pazopanib|DRUG: pazopanib|DRUG: pazopanib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double-Blind, Vehicle-Controlled, Multicenter Safety and Efficacy Study of Intraprostatic PRX302 for LUTS BPH
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: PRX302|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sargramostim With Ipilimumab Containing Therapy in Patients With Solid Tumors
Status: WITHDRAWN
Conditions: Solid Tumor|Solid Tumor, Adult
Interventions: BIOLOGICAL: Sargramostim|BIOLOGICAL: Ipilimumab-containing therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alveolar Ridge Preservation With Polycaprolactone Scaffold for Implant Site Development
Status: COMPLETED
Conditions: Alveolar Ridge Resorption After Extraction
Interventions: DEVICE: Polycaprolactone Scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Side Effects of 4 Times Bone Marrow Mono Nuclear Transplantation in Patients With Ischemic Lower Limb
Status: COMPLETED
Conditions: Ischemic Ulcer
Interventions: BIOLOGICAL: 4times injection|BIOLOGICAL: stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Use of a Mobile Tool in Improving Lifestyles
Status: COMPLETED
Conditions: Healthy Subjects Without Cardiovascular Disease
Interventions: DEVICE: Smartphone with APP|BEHAVIORAL: Counseling on lifestyles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Chronic Versus Intermittent Deep Brain Stimulation for Essential Tremor
Status: COMPLETED
Conditions: Essential Tremor
Interventions: DEVICE: Deep Brain Stimulation (Model 7438 Therapy Controller)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study on the Efficacy and Safety of Benzonatate Soft Capsules for Improving Adult Cough Symptoms
Status: UNKNOWN
Conditions: Cough
Interventions: DRUG: Benzonatate 200 mg|DRUG: blank control 0mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Ascending Dose Study With a Dose Formulation Comparison Cohort to Evaluate the Safety, Tolerability, and Pharmacokinetics of TBA-354 in Healthy Adult Subjects
Status: TERMINATED
Conditions: Tuberculosis
Interventions: DRUG: TBA-354|DRUG: TBA-354 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Nicotine Plasma Concentrations and Subjective Effects for Three Electronic Cigarettes vs Combustible Cigarettes and Nicotine Gum
Status: COMPLETED
Conditions: Smoking
Interventions: OTHER: Own Brand Cigarette|OTHER: Electronic Cigarette #1|OTHER: Electronic Cigarette #2|OTHER: Electronic Cigarette #3|OTHER: Leading U.S. Nicotine Gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Self-Monitoring of Carbon Monoxide to Enhance Reproductive Outcomes in Women
Status: TERMINATED
Conditions: Pregnancy|Smoking|Smoking Cessation
Interventions: DEVICE: piCO+ Smokerlyzer® monitor|OTHER: Text messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Three Multiple-dose Regimens of BIA 9 1067 at Steady-state on the Levodopa Pharmacokinetics
Status: COMPLETED
Conditions: Parkinson's Disease (PD)
Interventions: DRUG: BIA 9-1067 5 mg|DRUG: BIA 9-1067 25 mg|DRUG: levodopa/carbidopa 100/25|DRUG: Placebo|DRUG: levodopa/benserazide 100/25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-PD-L1 and SAbR for Ovarian Cancer
Status: TERMINATED
Conditions: Recurrent Epithelial Cancer of Ovary|Primary Peritoneal Carcinoma|Fallopian Tube Cancer
Interventions: DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Control Systems Approach to Predicting Individualized Dynamics of Nicotine Cravings
Status: UNKNOWN
Conditions: Nicotine Addiction|Cigarette Smoking
Interventions: DRUG: Nicotine|DEVICE: MR Compatible Nicotine Delivery Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study on Preliminary Safety and Efficacy of the ARC-IM Therapy to Alleviate Locomotor Deficits in People With Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: ARC-IM System implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of SKY Breath Meditation on Health and Well-being
Status: ACTIVE_NOT_RECRUITING
Conditions: Stress|Stress, Psychological|Stress, Physiological|Anxiety|Mental Well Being|Happiness|Resilience
Interventions: BEHAVIORAL: SKY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The KNEEhabilitation Study: Improving Disability in Individuals With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Transcutaneous Electrical Nerve Stimulation|OTHER: Therapeutic Exercise|DEVICE: Sham Transcutaneous Electrical Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CHLORHEXIDINE GLUCONATE AND POVIDONE IODINE
Status: COMPLETED
Conditions: Evaluate to Effects of Two Antiseptic Products and Showering
Interventions: OTHER: incision side cleaning with antiseptic products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Effect of Neurofeedback Targeting EEG Theta / Beta Activities on the Strengthening of Wakefulness Maintenance Capacities and Cognitive Performance.
Status: COMPLETED
Conditions: Sleep Deprivation
Interventions: BEHAVIORAL: Neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: PK Study of Single-Dose ZTI-01 in Children (<12 Years of Age)
Status: RECRUITING
Conditions: Pediatric ALL
Interventions: DRUG: ZTI-01 100 mg/kg|DRUG: ZTI-01 75 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Immunogenicity of Recombinant Protein RBD Fusion Dimer Vaccine Against the Virus That Cause COVID-19, Known as Severe Acute Respiratoy Syndrome Coronavirus 2 (SARS-CoV-2)
Status: COMPLETED
Conditions: COVID-19|SARS-CoV-2 Acute Respiratory Disease
Interventions: BIOLOGICAL: COVID-19 Vaccine HIPRA|BIOLOGICAL: Cominarty (Pfizer-BioNtech)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Fallopian Tube Endometrioid Adenocarcinoma|Fallopian Tube High Grade Serous Adenocarcinoma|FIGO Stage III Ovarian Cancer 2014|FIGO Stage IV Ovarian Cancer 2014|Ovarian Carcinoma|Primary Peritoneal Endometrioid Adenocarcinoma|Primary Peritoneal High Grade Serous Adenocarcinoma|Ovarian High Grade Serous Adenocarcinoma
Interventions: DRUG: Olaparib|BIOLOGICAL: Bevacizumab|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Using Hypoxia-adjusted Radiotherapy
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: RADIATION: DE-HyART|RADIATION: Standard Arm|DRUG: Cisplatin injection|RADIATION: Standard fractionation (Radiation Oncology preference)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining the Effects of Parenting Interventions on Children With Attention-Deficit / Hyperactivity Disorder (AD/HD) and Their Parents
Status: COMPLETED
Conditions: Parenting Intervention|ADHD|Emotion Regulation
Interventions: BEHAVIORAL: Mindful Parenting, Tuning in to Kids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bovine-derived Xenograft With or Without L-PRF for Alveolar Ridge Preservation After Tooth Extraction: a Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Dental Implants|Tooth Extraction|Bone Regeneration
Interventions: PROCEDURE: Alveolar ridge preservation using sticky bone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Personal Pharmacogenomic Testing as an Educational Tool in the Pharmacy Curriculum
Status: COMPLETED
Conditions: Healthy
Interventions: GENETIC: Personal genomic educational testing (PGET)|GENETIC: No personal genomic educational testing (NPGET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Measurement of Total Retinal Blood Flow in Patients With Diabetes and Healthy Subjects
Status: COMPLETED
Conditions: Type I Diabetes
Interventions: DEVICE: FDOCT|OTHER: Dynamic Vessel Analyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pre-operative Carbohydrate Loading Patients With Diabetes Undergoing Elective Colorectal Surgery
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: 40g carbohydrate load (Apple juice)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: MEDI4736 (Durvalumab) in Patients With Brain Metastasis From Epithelial-derived Tumors
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer|Nonsmall Cell Lung Cancer|Breast Cancer|Cancer of Breast|Cancer of the Breast|Gastroesophageal Cancer|Pancreatic Cancer|Cancer of the Pancreas|Colorectal Cancer|Colorectal Carcinoma|Renal Cancer|Kidney Cancer|Cancer of the Kidney|Cancer of Kidney|Ovarian Cancer|Ovary Cancer|Cancer of the Ovary|Cancer of Ovary
Interventions: DRUG: MEDI4736
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CHIlled Platelet Study "CHIPS"
Status: RECRUITING
Conditions: Acute Blood Loss
Interventions: BIOLOGICAL: Cold Stored Platelets|BIOLOGICAL: Room Temperature Platelets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Undenatured Cysteine-Rich Whey Protein Isolate (HMS 90®) in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Parkinsonian Disorders|Basal Ganglia Diseases|Brain Diseases|Central Nervous System Diseases|Nervous System Diseases|Movement Disorders|Neurodegenerative Diseases
Interventions: DIETARY_SUPPLEMENT: Whey protein|DIETARY_SUPPLEMENT: Soy protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Glycemic and Metabolic Responses of Frozen Yogurt Containing Saskatoon Berry Powder in Healthy Males and Females
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Saskatoon Berry Frozen Yogurt|DIETARY_SUPPLEMENT: Frozen Yogurt|DIETARY_SUPPLEMENT: Control 1|DIETARY_SUPPLEMENT: Control 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FMBI With War-affected Families
Status: COMPLETED
Conditions: Family Mindfulness-based Intervention in War-affected Families|Intergenerational Trauma|War-Related Trauma
Interventions: BEHAVIORAL: Learning to BREATHE|BEHAVIORAL: After Deployment Adaptive Parenting Tools (ADAPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Naloxone Auto-injection in Healthy Volunteers
Status: COMPLETED
Conditions: Overdose Antidote
Interventions: COMBINATION_PRODUCT: Naloxone hydrochloride injection solution, SmartDose wearable auto injector and mobile respiratory sensing system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prospective Evaluation of Hypofractionation Proton Beam Therapy With Concurrent Treatment of the Prostate and Pelvic Nodes for Clinically Localized, High Risk or Unfavorable Intermediate Risk Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Hypofractionation Proton beam therapy with Concurrent Treatment of the Prostate and Pelvic Nodes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Anxiety After a Session of Energy Resonance by Cutaneous Stimulation
Status: NOT_YET_RECRUITING
Conditions: Breast Neoplasm
Interventions: OTHER: Energy Resonance by Cutaneous Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Effect of Virtual Reality Application on Postoperative Pain and Anxiety in Women Aged 50-70
Status: NOT_YET_RECRUITING
Conditions: Pain Management After Surgery
Interventions: OTHER: Providing VR experience
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagus
Status: RECRUITING
Conditions: Esophageal Stricture
Interventions: COMBINATION_PRODUCT: GIE Medical ProTractX3 TTS DCB|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Low vs. Standard Daily Doses of Antiepileptic Drugs in Newly Diagnosed, Previously Untreated Epilepsy(STANDLOW)
Status: ACTIVE_NOT_RECRUITING
Conditions: Epilepsies, Partial
Interventions: DRUG: Low dose carbamazepine|DRUG: Standard dose carbamazepine|DRUG: Low dose levetiracetam|DRUG: Standard dose levetiracetam|DRUG: Low dose valproate|DRUG: Standard dose valproate|DRUG: Low dose zonisamide|DRUG: Standard dose zonisamide|DRUG: Low dose oxcarbazepine|DRUG: Standard dose oxcarbazepine|DRUG: Low dose topiramate|DRUG: Standard dose topiramate|DRUG: Low dose lamotrigine|DRUG: Standard dose lamotrigine|DRUG: Low dose gabapentin|DRUG: Standard dose gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RRx-001 Given With Irinotecan and Temozolomide for Pediatric Patients With Recurrent or Progressive Malignant Solid and Central Nervous System Tumors
Status: TERMINATED
Conditions: Brain Tumor, Recurrent|Brain Tumor, Pediatric|Central Nervous System Neoplasms|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: RRx-001|DRUG: Temozolomide|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manual Lymphatic Drainage in Fibromyalgia Syndrome
Status: RECRUITING
Conditions: Fibromyalgia
Interventions: OTHER: Manual Lymphatic Drainage|DRUG: Medical treatment|OTHER: Sham Manual Lymphatic Drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PraSugrel vs TicagrElor in ST-Elevation Myocardial Infarction paTients With Diabetes Mellitus
Status: COMPLETED
Conditions: ST-Elevation Myocardial Infarction
Interventions: DRUG: ticagrelor|DRUG: prasugrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This Study Tests the New Medicine BI 754111 Alone or in Combination With Another New Substance BI 754091 in Patients With Advanced Cancer. The Study Tests Different Doses to Find the Best Dose for Continuous Treatment.
Status: COMPLETED
Conditions: Neoplasms|Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: BI 754111|DRUG: BI 754091
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bifidobacterium Infantis M-63 Improves Mental Health in Irritable Bowel Syndrome Developed After a Major Flood Disaster
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Abdominal Pain|Small Intestinal Bacterial Overgrowth
Interventions: DIETARY_SUPPLEMENT: Probiotics M-63|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Support for Cardiovascular Health in African American Primary Care Patients
Status: COMPLETED
Conditions: Cardiovascular Diseases|Blood Pressure
Interventions: BEHAVIORAL: Peer Coach Phone Calls|BEHAVIORAL: Health Educator Visits|OTHER: written materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Enasidenib in Combination With Cobimetinib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Cobimetinib|DRUG: Enasidenib Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of Olpasiran in Participants With Normal Renal Function and Participants With Various Degrees of Renal Impairment
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: Olpasiran
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase I Study to Evaluate the Pharmacokinetics, Safety and Antiviral Effects of Concurrent Administration of Zidovudine (AZT) and 2'3'-Dideoxyinosine (ddI) in Patients With Human Immunodeficiency Virus (HIV)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety/Feasibility of Autologous Mononuclear Bone Marrow Cells in Stroke Patients
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: BIOLOGICAL: Autologous Bone Marrow Mononuclear Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Assessment of T2347 Versus Xalacom® in Ocular Hypertensive or Glaucomatous Patients
Status: COMPLETED
Conditions: Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: T2347|DRUG: Xalacom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FREEDOM - A Frequent Optimization Study Using the QuickOpt Method
Status: COMPLETED
Conditions: Cardiac Arrhythmias|Heart Failure
Interventions: DEVICE: Control|DEVICE: QuickOpt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Systemic Psychotherapy-informed Self-help and Paraprofessional Training in a Naturalistic Setting
Status: RECRUITING
Conditions: Psychological Distress
Interventions: BEHAVIORAL: Systemic Psychotherapy-informed Growth Path|BEHAVIORAL: Systemic Psychotherapy-informed Listener Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate and Compare Alendronate and Risedronate on Bone Mineral Density in Women With Postmenopausal Osteoporosis (MK-0217-211)
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Alendronate|DRUG: Risedronate 35 mg|DIETARY_SUPPLEMENT: Elemental Calcium|DIETARY_SUPPLEMENT: Vitamin D|DRUG: Risendronate placebo|DRUG: Alendronate placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Effect of Albiglutide With Exenatide on Regional Brain Activity Related to Nausea in Healthy Subjects
Status: TERMINATED
Conditions: Diabetes Mellitus
Interventions: DRUG: Albiglutide 50mg|DRUG: Albiglutide matching placebo|DRUG: Exenatide 10microgram|DRUG: Exenatide placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Heart Failure With Preserved Ejection Fraction|Kidney Diseases|Heart Failure
Interventions: DRUG: Dapagliflozin 10 MG [Farxiga]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Miltefosine Plus Topical Imiquimod to Treat Cutaneous Leishmaniasis
Status: COMPLETED
Conditions: Cutaneous Leishmaniasis
Interventions: DRUG: Miltefosine + Imiquimod|DRUG: Miltefosine 150 mg x day + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Immunotherapy With Axitinib in Advanced Collecting Duct Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Collecting Duct Carcinoma
Interventions: DRUG: PD-(L)1 inhibitor|DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SilverCloud as a School-Based Intervention for Vulnerable Youth
Status: RECRUITING
Conditions: Depression|Anxiety
Interventions: BEHAVIORAL: App-based Cognitive Behavioral Therapy (CBT)|BEHAVIORAL: Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Acute Effect Of Different Kinesiological Tape
Status: COMPLETED
Conditions: Chronic Back Pain
Interventions: DEVICE: The Acute Effect Of Different Kinesiological Tape Application On Pain, Functional Performance And Trunk Endurance In Young Adults With Chronic Back Pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Transformation of Paralysis to Stepping
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DRUG: Buspirone|DEVICE: Non-invasive Spinal Cord Stimulation|DEVICE: Ekso Bionics Exoskeleton|DEVICE: Gravity Neutral Device|DEVICE: Body Weight Supported Treadmill Training|DEVICE: Rolling Walker
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacoeconomics in the Application of 5-azacitidine in the Treatment of Myelodysplastic Syndromes and Acute Myeloid Leukemia
Status: WITHDRAWN
Conditions: Myelodysplastic Syndromes|Acute Myeloid Leukemia
Interventions: DRUG: 5-azacitidine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Imaging Pituitary ActiVation by Exendin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: RADIATION: Ga-68-NODAGA-exendin-4 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Single Arm Phase 2 Study to Evaluate Efficacy and Safety of Trastuzumab Deruxtecan for Patients With HER2 Mutant NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2-mutant Non-Small Cell Lung Cancer
Interventions: DRUG: Trastuzumab deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Naltrexone Use in Patients With POTS
Status: NOT_YET_RECRUITING
Conditions: Postural Orthostatic Tachycardia Syndrome
Interventions: DRUG: Low Dose Naltrexone|DRUG: Microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ⅲ Clinical Trial of Buagafuran Capsules in the Treatment of GAD
Status: RECRUITING
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: Buagafuran capsules, 15mg/ capsule|DRUG: Buspirone tablets, 5mg/ tablet|DRUG: Buagafuran capsules mimic, 0mg/ capsule|DRUG: Buspirone tablets mimic, 0mg/ tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PreOxygenation for EndoTracheal Intubations
Status: TERMINATED
Conditions: Intubation Complication|Preoxygenation|Hypoxemia
Interventions: DEVICE: Non-rebreather oxygen mask|DEVICE: Bag-valve-mask|DEVICE: High Flow Nasal Cannulae
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety, Tolerability and Pharmacokinetics of GLPG2451 in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG2451 multiple dose|DRUG: Placebo multiple dose|DRUG: GLPG2451/GLPG2222 multiple dose|DRUG: Combined Placebo multiple dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anamorelin HCl in the Treatment of Non-Small Cell Lung Cancer-Cachexia (NSCLC-C): An Extension Study (ROMANA 3)
Status: COMPLETED
Conditions: Cachexia|Non-Small Cell Lung Cancer
Interventions: DRUG: Anamorelin HCl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Pharmacokinetics of Oral Sodium Oligo-mannurarate (GV-971) in Healthy Chinese Subjects
Status: UNKNOWN
Conditions: Pharmacokinetics|Safety
Interventions: DRUG: GV-971|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: eHealth Intervention on Physical Activity for Type 2 Diabetics - Frustrated by COVID-19
Status: UNKNOWN
Conditions: Type2 Diabetes
Interventions: BEHAVIORAL: eHealth +counselling contacts|BEHAVIORAL: eHealth|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Safety and Effectiveness of Epoetin Alfa in Facilitating Self-donation of Blood Before Surgery in Patients Who Are Undergoing Orthopedic Surgery and Who Have Low Hematocrit Levels (the Percent of Red Blood Cells in Whole Blood)
Status: COMPLETED
Conditions: Anemia|Blood Transfusion|Orthopedic Procedures
Interventions: DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Conduction Auditory Performance Via the Tooth for Single-Sided Deafness
Status: COMPLETED
Conditions: Unilateral Hearing Loss
Interventions: DEVICE: The Sonitus Bone Conduction Hearing System|DEVICE: SoundBite|DEVICE: SoundBite Hearing System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 'Oral Microbiome -Dietary Nitrate' Interactions and Cognitive Health in Older Age
Status: COMPLETED
Conditions: Dietary Supplementations
Interventions: DIETARY_SUPPLEMENT: Beetroot|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia
Status: RECRUITING
Conditions: Endometrial Carcinoma|Obesity|EIN|Endometrial Intraepithelial Neoplasia|Endometrial Cancer Stage I
Interventions: OTHER: CONCURRENT LAPAROSCOPIC HYSTERECTOMY AND WEIGHT LOSS SURGERY-Referral
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Effect of Three Types of Rapid Maxillary Expanders (Conventional, Hybrid and MSE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Maxillary Retrusion|Nasal Airway Obstruction
Interventions: DEVICE: CH 4 band|DEVICE: HH 2 bands|DEVICE: MSE 2 bands and 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Potassium Bicarbonate Supplementation on Bone and Muscle in Older Adults
Status: COMPLETED
Conditions: Osteoporosis|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Potassium Bicarbonate|DIETARY_SUPPLEMENT: Sodium Bicarbonate|DIETARY_SUPPLEMENT: Potassium Chloride|DIETARY_SUPPLEMENT: placebo (microcrystalline cellulose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Compare Bevacizumab in Combination With Erlotinib Versus Erlotinib Alone in NSCLC Patients Activating EGFR Mutations
Status: UNKNOWN
Conditions: NSCLC
Interventions: DRUG: Bevacizumab|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of EXL01, a New Live Biotherapeutic Product to Prevent Recurrence of Clostridioides Difficile Infection in High-risk Patients
Status: RECRUITING
Conditions: Clostridioides Difficile Infection|Recurrent Infection
Interventions: DRUG: EXL01|DRUG: EXL01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sodium Hyaluronate and Wavefront Aberrations in Dry Eyes
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: 0.18% sodium hyaluronate|DRUG: 0.9% sodium chloride solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Cardiovascular Effects of Nitrogen Dioxide Exposure
Status: COMPLETED
Conditions: Endothelial Dysfunction
Interventions: PROCEDURE: Forearm Vascular Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Imaging Lymphatic/Cerebrospinal Fluid (CSF) Drainage From the Head and Neck in Persons With Traumatic Brain Injury: Demonstration of Feasibility and Evaluation of Manual Therapy to Improve Drainage and Facilitate Cognitive Recovery
Status: UNKNOWN
Conditions: Trauma, Brain|Neuroinflammation
Interventions: OTHER: Manual Lymphatic Drainage (MLD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ginkgo Biloba and Ocular Blood Flow in Primary Open-angle Glaucoma
Status: COMPLETED
Conditions: Glaucoma, Open-Angle
Interventions: DRUG: Ginkgo biloba|DRUG: Placebo to Ginkgo biloba
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FAST GFR: Pilot Study to Evaluate the Safety of the FAST GFR Test in Patients.
Status: COMPLETED
Conditions: Chronic Kidney Disease|Acute Kidney Injury
Interventions: DEVICE: 75 mg / 6 mL VFI™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Addiction Housing Case Management for Homeless Veterans
Status: COMPLETED
Conditions: Homelessness|Substance Abuse Disorders|Mental Disorders
Interventions: BEHAVIORAL: Intensive Addiction/Housing Case Management|BEHAVIORAL: Housing Support Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Effect of a Speech Detection Tool on the Improvement of Phonation in Neuromuscular Patients Dependent on Mechanical Ventilation
Status: UNKNOWN
Conditions: Neuromuscular Diseases|Mechanical Ventilation|Speech
Interventions: DEVICE: speech trials during different ventilation conditions|OTHER: speech trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevention of Urinary Tract Infection (UTI) in Persons With Spinal Cord Injury (SCI)
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: PROCEDURE: bacterial interference
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of Single Dose Bevacizumab as Treatment for Acute Respiratory Distress Syndrome (ARDS) in COVID-19 Patients
Status: TERMINATED
Conditions: ARDS, Human|Coronavirus Infection
Interventions: DRUG: Bevacizumab|DRUG: BAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of IAH0968 in Patients With HER2-positive Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: IAH0968|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Schistosomiasis Sm14-vaccine in Senegal
Status: RECRUITING
Conditions: Schistosomiasis Mansoni|Schistosomiasis Haematobium|Vaccination; Infection
Interventions: BIOLOGICAL: Sm14 recombinant vaccine+ GLA-SE adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: AntiPlatelet theraPy stratEgy followiNg Left Atrial appenDAGe closurE
Status: RECRUITING
Conditions: Atrial Fibrillation|Atrial Appendage|Anticoagulants|Stroke|Platelet Aggregation Inhibitors
Interventions: DRUG: Double antiplatelet therapy|DRUG: Aspirin|DEVICE: Brain MRI|OTHER: Neurological tests
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pudendal Nerve Block in Vaginal Surgery
Status: COMPLETED
Conditions: Nerve Block|Pain, Postoperative|Pelvic Floor Disorders|Pelvic Organ Prolapse|Pudendal Neuralgia|Surgery
Interventions: PROCEDURE: Pudendal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Determine the Effect of Simulation Based Training on Initial Performance of Ultrasound Guided Axillary Brachial Plexus Blockade in a Clinical Setting
Status: TERMINATED
Conditions: Anesthesiology Training
Interventions: OTHER: Simulation based training|OTHER: Traditional training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azacitidine + Lenalidomide Combo in the Elderly With Previously Treated AML & High-Risk MDS
Status: TERMINATED
Conditions: Leukemia|Acute Myeloid Leukemia (AML)|Myelodysplastic Syndromes (MDS)
Interventions: DRUG: Azacitidine|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP1)
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Therapy|DRUG: Midomafetamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intracoronary Infusion of Mononuclear Cells Autologous Bone Marrow in Patients With Chronic Coronary Occlusion and Ventricular Dysfunction, Previously Revascularized.
Status: COMPLETED
Conditions: Coronary Atherosclerosis and Other Heart Disease
Interventions: OTHER: Mononuclear cells from autologous bone marrow|DRUG: Conventional medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prostate Cancer Monitoring Using [18F]DCFPyL and Blood Based Biomarkers
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: [F-18] DCFPyL|PROCEDURE: PET/CT imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Psychoeducation for the Prevention of PTSD
Status: WITHDRAWN
Conditions: Psychoeducation on Trauma Reactions|Psychoeducation on Safety Behaviors and How to Fade Them|Monitoring-only Control
Interventions: BEHAVIORAL: Psychoeducation on trauma reactions|BEHAVIORAL: Psychoeducation on safety behaviors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Contrast-enhanced Ultrasound Versus CT Scan for Kidney Stone Patient Management
Status: WITHDRAWN
Conditions: Ultrasonography|Nephrolithiasis
Interventions: DRUG: CEUS|DIAGNOSTIC_TEST: Non-contrast CT scan|DIAGNOSTIC_TEST: Capping trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Radical Resection Vs. Ablative Stereotactic Radiotherapy in Patients With Operable Stage I NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: RADIATION: Stereotactic Body Radiation Therapy (SBRT)|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: M-mode Ultrasonography for Epidural Catheter Identification and Confirmation of Correct Catheter Position
Status: COMPLETED
Conditions: Epidural Analgesia for Labour and Delivery
Interventions: OTHER: Location of the epidural analgesia catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Risedronate in Improving Bone Mineral Density and Bone Health in Postmenopausal Women With Ductal Carcinoma In Situ Enrolled in Clinical Trial CRUK-IBIS-II-DCIS
Status: WITHDRAWN
Conditions: Breast Cancer|Osteoporosis
Interventions: DRUG: risedronate sodium|OTHER: diagnostic laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety & Efficacy Study of Subcutaneous Tetrodotoxin for Moderate to Severe Inadequately Controlled Cancer-related Pain
Status: COMPLETED
Conditions: Pain|Cancer
Interventions: BIOLOGICAL: Tetrodotoxin|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Combined Modality Treatment in Primary Central Nervous System Lymphoma
Status: COMPLETED
Conditions: Lymphoma, B Cell
Interventions: DRUG: high dose methotrexate|DRUG: high dose cytarabine|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beta-1,3/1,6-D-Glucan Ganoderma Lucidum on Non-infectious and Idiopathic Uveitis
Status: UNKNOWN
Conditions: Uveitis
Interventions: DRUG: Beta-1,3/1,6-D-Glucan Ganoderma lucidum|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the ADR With Air Insufflation, Water Immersion and Water Exchange During Two-endoscopist Colonoscopy
Status: COMPLETED
Conditions: Adenoma
Interventions: PROCEDURE: Air insufflation|PROCEDURE: water immersion|PROCEDURE: water exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Liposomal Daunorubicin in Treating Patients With HIV-Related Kaposi's Sarcoma
Status: TERMINATED
Conditions: Sarcoma
Interventions: DRUG: liposomal daunorubicin citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Niclosamide and Enzalutamide in Treating Patients With Castration-Resistant, Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Castration Levels of Testosterone|Castration-Resistant Prostate Carcinoma|Metastatic Prostate Carcinoma|Recurrent Prostate Carcinoma|Stage IV Prostate Adenocarcinoma
Interventions: DRUG: Enzalutamide|OTHER: Laboratory Biomarker Analysis|DRUG: Niclosamide|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT