pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of a Valved Feeding System in Late-preterm Newborns: the Safe Oral Feeding Trial
Status: COMPLETED
Conditions: Premature Birth|Feeding; Difficult, Newborn|Feeding, Bottle
Interventions: DEVICE: Valved ergonomic teat|DEVICE: Standard silicon teat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Traditional Chinese Medicine (TCM) Comprehensive Therapy in Patients With Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Treatment of MTX and HCQ|DRUG: Treatment of TCM|DRUG: Integrative Medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SCD-Haplo: Phase II Study of HLA-Haploidentical SCT for Aggressive SCD
Status: TERMINATED
Conditions: Sickle Cell Disease
Interventions: PROCEDURE: Haploidentical Transplant|DRUG: Alemtuzumab|RADIATION: Total Body Irradiation|DRUG: Cyclophosphamide|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of HPV Infection in Perimenopausal and Postmenopausal Women
Status: NOT_YET_RECRUITING
Conditions: HPV Infection
Interventions: DRUG: Human interferon alpha 2b vaginal Effervescent capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glofitamab With Pirtobrutinib for Relapsed or Refractory Mantle Cell Lymphoma
Status: RECRUITING
Conditions: Mantle Cell Lymphoma
Interventions: BIOLOGICAL: Obinutuzumab|BIOLOGICAL: Glofitamab|DRUG: Pirtobrutinib|PROCEDURE: Tumor Imaging|PROCEDURE: Biospecimen Collection|DEVICE: ClonoSeq Assay|PROCEDURE: Bone Marrow Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dosimetry Study of I-131-CLR1404 in Patients With Relapsed or Refractory Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: I-131-CLR1404
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Citrulline and Protein Metabolism in the Malnourished Elderly People
Status: COMPLETED
Conditions: Metabolism|Elderly
Interventions: DIETARY_SUPPLEMENT: Citrulline|DIETARY_SUPPLEMENT: Amino acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Osseodensification Versus Motor-Driven Expanders' Techniques for Increasing Bone Density With Simultaneous Implant Placement
Status: COMPLETED
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: Osseodensification technique|PROCEDURE: Motor driven expanders' technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Biobehavioral Intervention for Latino/Hispanic Young Adults With Cancer
Status: RECRUITING
Conditions: Cancer
Interventions: BEHAVIORAL: Goal-Focused Emotion-Regulation Therapy (GET)|BEHAVIORAL: Individual Supportive Listening (ISL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Induction Chemo-Nivo in Unresectable Stage III NSCLC
Status: RECRUITING
Conditions: Lung Cancer, Nonsmall Cell|Lung Cancer Stage III
Interventions: COMBINATION_PRODUCT: Nivolumab and Chemotherapy|DRUG: Nivolumab|PROCEDURE: Post Induction Surgery|RADIATION: Post Induction XRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Antimicrobial Fiber Reinforced Composite Resin Space Maintainer Modified With Silver Nano Particles
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Caries in Children
Interventions: DEVICE: Fiber reinforced composite resin space maintainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Three Grams Daily Valacyclovir in Patients With Chronic Hepatitis C and HSV-2 Infection (Phase I)
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection
Interventions: DRUG: Valacyclovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Management After Shoulder Prosthesis: A Clinical Trial of Nerve Block and Local Infiltration
Status: TERMINATED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Local infiltration analgesia|PROCEDURE: Interscalene catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of the PoNS™ Device in the Treatment of Blunt and Blast Induced Vestibular Disorders
Status: WITHDRAWN
Conditions: Hearing and Vestibular Disorders
Interventions: OTHER: Placebo device|DEVICE: PoNS™ device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TY-2136b in Patients With Advanced Solid Tumors Harboring ALK, ROS1 or NTRK1-3 Alterations
Status: RECRUITING
Conditions: Locally Advanced Solid Tumor|Metastatic Solid Tumor
Interventions: DRUG: TY-2136b|DRUG: TY-2136b
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibody Treatment for Advanced Celiac Disease
Status: COMPLETED
Conditions: Celiac Disease|Celiac Sprue|Gluten Enteropathy|Gluten-Sensitive Enteropathy
Interventions: BIOLOGICAL: Hu-Mik- Beta-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Special Drug Use Investigation for CLAVAMOX® (Amoxicillin/Clavulanate) Pediatrics Dry Syrup (Every Indication Excluded Otitis Media)
Status: COMPLETED
Conditions: Otitis Maedia
Interventions: DRUG: Amoxicillin and clavulanate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gemcitabine and Cisplatin With/Without Anlotinib in Advanced Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Gemcitabine/Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MULTivessel Immediate Versus STAged RevaScularization in Acute Myocardial Infarction -The MULTISTARS AMI Trial
Status: COMPLETED
Conditions: ST-elevation Myocardial Infarction|Multivessel Coronary Disease
Interventions: PROCEDURE: Staged complete PCI|PROCEDURE: Immediate complete PCI|DEVICE: Synergy™ stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Prophylactic Measures on the Occurrence of Pre-eclampsia (OP-PE)
Status: COMPLETED
Conditions: Pregnancy Complications
Interventions: OTHER: Oral prophylactic intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Topical Vancomycin Over Sternal Edge in Cardiac Surgery
Status: RECRUITING
Conditions: Sternal Wound Infection
Interventions: DRUG: Vancomycin Hydrochloride|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Coronary Bypass and Artotic Leaflet Surgery : Heparin Low Dose vs Full Dose
Status: COMPLETED
Conditions: Cardiac Surgery|Extracorporeal Circulation
Interventions: DRUG: Heparin Low Dose|DRUG: Heparin Full Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multiple Interventions to Prevent Cognitive Decline
Status: UNKNOWN
Conditions: Cognitive Dysfunction|Cognition Disorders|Memory Disorders
Interventions: OTHER: Cognitive training|BEHAVIORAL: Physical activity|BEHAVIORAL: Nutrition education|BEHAVIORAL: Adaption to memory loss|DIAGNOSTIC_TEST: Diagnosis of hearing impairment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Reduced Immunosuppressive Therapy With or Without Donor White Blood Cells in Treating Patients With Lymphoproliferative Disease After Organ Transplantation
Status: UNKNOWN
Conditions: Lymphoproliferative Disorder
Interventions: BIOLOGICAL: therapeutic allogeneic lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A STUDY TO EVALUATE THE EFFICACY OF CJH1 (CLR4001) IN PARKINSON'S DISEASE
Status: UNKNOWN
Conditions: Parkinson's Disease
Interventions: DRUG: CJH1 (CLR4001)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development of Adaptive Deep Brain Stimulation for OCD (Phase 1a)
Status: ACTIVE_NOT_RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Activa PC+S DBS implant for OCD|OTHER: One Month Blinded Discontinuation Period
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Biologic Activity of XOMA 052 in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: XOMA 052|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Performance of Chest Computed Tomography Scan in Patients Aged 65 and Over Presenting to Emergency Room With Acute Dyspnea
Status: NOT_YET_RECRUITING
Conditions: Dyspnea
Interventions: OTHER: CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Assess New Ebola Vaccines, cAd3-EBO Z and MVA-BN® Filo
Status: COMPLETED
Conditions: Ebola|Ebola Zaire
Interventions: BIOLOGICAL: cAd3-EBO Z at 1 x 10^10 vp|BIOLOGICAL: cAd3-EBO Z at 2.5 x 10^10 vp|BIOLOGICAL: cAd3-EBO Z at 5 x 10^10 vp|BIOLOGICAL: 4.4x10^8 TCID50s MVA-BN® Filo|BIOLOGICAL: 2.2x10^8 TCID50s MVA-BN® Filo|BIOLOGICAL: 4.4 x 10^7 TCID50s MVA-BN® Filo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of the Neovasc Coronary Sinus Reducer System for the Treatment of Refractory Angina Pectoris in Patients With Ngina Class 3-4 Who Are Not Candidates for Revascularization
Status: RECRUITING
Conditions: Refractory Angina
Interventions: DEVICE: Neovac coronary sinus reducer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CHM Teabag Decrease Stroke Risk Among Hong Kong Elderly
Status: RECRUITING
Conditions: Stroke|Risk Reduction|Elderly
Interventions: DRUG: Chinese Herbal Medicine (CHM) teabag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Novasight Hybrid Intravascular Ultrasound and Optical Coherence Tomography System (IVUS OCT)
Status: COMPLETED
Conditions: Stable Angina|Acute Coronary Syndrome
Interventions: DEVICE: Observation group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Behavior Change and Digital Health Interventions for Improved TB Treatment Outcomes
Status: COMPLETED
Conditions: Tuberculosis|Adherence, Patient|Adherence, Medication|Drug-resistant Tuberculosis
Interventions: BEHAVIORAL: Keheala Mobile Health Platform and Behavioral Interventions|BEHAVIORAL: Social and Behavior Change Communication (SBCC)|BEHAVIORAL: SMS Reminder|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Distilled Water Versus Mitomycin C on Preventing Recurrences of Bladder Cancer After Transurethral Resection
Status: UNKNOWN
Conditions: Recurrent Superficial Bladder Cancer|Distilled Water
Interventions: DRUG: distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Cellular and Molecular Inflammatory Mechanisms Leading to Bone Resorption in Peri-implantitis Vs Periodontitis
Status: COMPLETED
Conditions: Peri-Implantitis|Periodontitis
Interventions: PROCEDURE: Crown lengthening|PROCEDURE: Open Flap Debridement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Influence of Repairing the Sub-scapularis on Outcomes After Reverse Arthroplasty
Status: ENROLLING_BY_INVITATION
Conditions: Severe Arthropathy With a Grossly Deficient Rotator Cuff
Interventions: PROCEDURE: Subscapularis repair|DEVICE: Shoulder implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: TRT on BPH Hypoganadal MetS Patients. Florence-PROTEST
Status: COMPLETED
Conditions: Prostatic Hyperplasia|Lower Urinary Tract Symptoms|Hypogonadism
Interventions: DRUG: Testosterone gel 2%|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Topical TolaSure on Skin Punch Biopsies in Healthy Participants
Status: COMPLETED
Conditions: Wound Healing
Interventions: DRUG: TolaSure Topical Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of X842 in Patients With Reflux Esophagitis
Status: UNKNOWN
Conditions: Reflux Esophagitis
Interventions: DRUG: X842|DRUG: X842 Placebo|DRUG: Lansoprazole|DRUG: Lansoprazole Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: COVID-19 Respiratory Outcomes Registry
Status: COMPLETED
Conditions: Covid19
Interventions: OTHER: Questionnaires and Patient Reported Outcomes (PROs)|DIAGNOSTIC_TEST: Nasal Swab COVID-19 reverse transcription polymerase chain reaction test (RT-PCR)|GENETIC: Blood Samples for Biomarkers|DIAGNOSTIC_TEST: High Resolution Computed Tomography|DIAGNOSTIC_TEST: Physical Exam and Vital Signs|DIAGNOSTIC_TEST: Medical Research Council Sum Score|DIAGNOSTIC_TEST: Hand Grip Strength|DIAGNOSTIC_TEST: Spirometry|DIAGNOSTIC_TEST: Diffusing Capacity of Carbon Monoxide|DIAGNOSTIC_TEST: 6 Minute Walk Test|DIAGNOSTIC_TEST: Sit to Stand (STS) Measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immediate Effects of Open and Closed Kinetic Chain Exercises on Upper Extremity in Stroke Patients.
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: Open Kinetic Chain Activity|OTHER: Closed Kinetic Chain Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does a Caffeine Gum Improve 5 km Run Performance in a Competition/Field Setting?
Status: COMPLETED
Conditions: Running Performance
Interventions: DIETARY_SUPPLEMENT: caffeine gum|DIETARY_SUPPLEMENT: placebo gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Transient Elastography (FibroTouch) for Assessing Risk of Gastroesophageal Varices Bleeding in Compensated Cirrhosis (Pan-CHESS1801)
Status: UNKNOWN
Conditions: Compensated Liver Cirrhosis|Gastroesophageal Varices Bleeding
Interventions: DIAGNOSTIC_TEST: Liver sitffness measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Baerveldt (BGI) Valve Versus Ahmed(AGV) Valve in Management of Difficult Glaucoma Cases
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Glaucoma Secondary|Glaucoma, Neovascular|Glaucoma, Angle-Closure
Interventions: DEVICE: glaucoma implant procedure (Baerveldt)|DEVICE: glaucoma implant procedure (Ahmed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of Single-Dose Intravenous Ustekinumab Delivered in 2 Different Liquid in Vial Formulations
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ustekinumab|DRUG: Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closed-loop in Adults With T2D Requiring Dialysis
Status: COMPLETED
Conditions: Type 2 Diabetes|End Stage Renal Disease
Interventions: DEVICE: CamAPS HX Closed-loop|OTHER: Multiple Daily Insulin Injections (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cultivating Healthy Environments in Families With Type 1 Diabetes (CHEF)
Status: COMPLETED
Conditions: Type I Diabetes
Interventions: BEHAVIORAL: Education|BEHAVIORAL: Problem Solving|BEHAVIORAL: Social Learning|BEHAVIORAL: Behavior Modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Cohort Study to Describe and Compare the Use of Darolutamide, Enzalutamide and Apalutamide and How Well These Work in Men With Non-metastatic Castration-resistant Prostate Cancer (nmCRPC) in Real World Settings
Status: COMPLETED
Conditions: Non-metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Apalutamide|DRUG: Darolutamide (BAY 1841788)|DRUG: Enzalutamide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial to Assess the Safety and Preliminary Efficacy of GEN1055 on Malignant Solid Tumors as Monotherapy and as Combination Therapy
Status: RECRUITING
Conditions: Malignant Solid Tumor
Interventions: BIOLOGICAL: GEN1055|BIOLOGICAL: Pembrolizumab|DRUG: Standard Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effect of Dexmedetomidine With Midazolam on Sedation, Oxidative Stress, and Microcirculation in Intensive Care Unit
Status: COMPLETED
Conditions: Sedation|Oxidative Stress
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam|DRUG: Dexmedetomidine, Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin and Capecitabine Versus Follow-up After Resection of Colorectal Liver Metastases
Status: UNKNOWN
Conditions: Colorectal Neoplasms|Liver Metastases
Interventions: DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A PK Study Testing Single Oral Dose of Elacestrant in Subjects With Normal or Severely Impaired Hepatic Function
Status: RECRUITING
Conditions: Hepatic Impairment
Interventions: DRUG: Elacestrant dihydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 2a Study of CAN-2409 With Standard Radiation Therapy for Malignant Glioma
Status: COMPLETED
Conditions: Malignant Glioma|Glioblastoma Multiforme|Anaplastic Astrocytoma|High Grade Glioma
Interventions: BIOLOGICAL: CAN-2409|DRUG: Valacyclovir|DRUG: Temozolomide|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of in Situ Terlipressin Administration Before the Realisation of Bronchial Biopsy
Status: UNKNOWN
Conditions: Bronchial Endoscopy
Interventions: DRUG: Terlipressin administration|PROCEDURE: bronchoscopy under local anesthesia|PROCEDURE: Biopsy sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Epidural Levobupivacaine-sufentanil Versus Epidural Levobupivacaine and Intravenous Ketamine
Status: TERMINATED
Conditions: Thoracic Surgery
Interventions: DRUG: Sufentanil|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation and Cohort Expansion Study of KB-0742 in Participants With Relapsed or Refractory Solid Tumors or Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Relapsed Solid Tumors|Refractory Solid Tumors|Non-Hodgkin Lymphoma
Interventions: DRUG: KB-0742
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irradiated Donor Lymphocytes and Rituximab in Treating Patients With Relapsed or Refractory Lymphoproliferative Disease
Status: TERMINATED
Conditions: Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: rituximab|BIOLOGICAL: therapeutic allogeneic lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Phase III Trial of Leukine® vs Neupogen® in Patients Receiving Cisplatin & Gemcitabine for Urothelial Cancer
Status: TERMINATED
Conditions: Bladder Cancer
Interventions: DRUG: gemcitabine|DRUG: cisplatin|DRUG: sargramostim|DRUG: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurocognitive Impact and Dose-Effect Relationship of Hippocampal Avoidance During Whole Brain Radiotherapy Plus Simultaneous Integrated Boost - A Prospective Follow-up Study
Status: RECRUITING
Conditions: Brain Metastasis|Brain Metastases
Interventions: RADIATION: hippocampal-sparing WBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of the Efficacy and Usability of the BELK Orthosis Knee Module in a Neurological Setting (BELK@CCP)
Status: WITHDRAWN
Conditions: Knee Instability|Neuromuscular Diseases|Central Nervous System Diseases|Stroke
Interventions: DEVICE: With knee exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Once Daily Dosing of Aliskiren (300 mg (qd) Once a Day) to Twice Daily Dosing of Aliskiren (150 mg (Bid) Twice a Day) in Treating Moderate Hypertension.
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Aliskiren|DRUG: Placebo to Aliskiren
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Monitoring Postprandial Glycemia in Fruit Snacks
Status: COMPLETED
Conditions: Blood Glucose
Interventions: DIETARY_SUPPLEMENT: Fruit snack 1|DIETARY_SUPPLEMENT: Fruit Snack 2|DIETARY_SUPPLEMENT: Fruit Snack 3|DIETARY_SUPPLEMENT: Fruit Snack 4|DIETARY_SUPPLEMENT: White Bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Reconstruction of Atrophic Maxillary Ridges Using Mandibular Blocks With and Without Coverage Using Collagen Membrane
Status: COMPLETED
Conditions: Bone Augmentation
Interventions: PROCEDURE: Onlay bone block covered using collagen membrane|PROCEDURE: Onlay bone block without collagen membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrent Membrane Sweeping With Dinoprostone Versus Dinoprostone in Labor Induction of Nulliparas at Term With an Unfavorable Cervix
Status: COMPLETED
Conditions: Nulliparous Women Who Scheduled for Labor Induction
Interventions: PROCEDURE: Concurrent membrane sweeping with Dinoprostone|DRUG: 10mg Dinoprostone vaginal insert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Laboratory Scan of Patients With Aortic Aneurysms to IgG4 Levels in the Blood
Status: UNKNOWN
Conditions: IgG4-related Disease|Aortic Aneurysm
Interventions: PROCEDURE: Blood Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Rosiglitazone on Bone in Postmenopausal Diabetic Women
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Obesity|Menopause
Interventions: DRUG: Rosiglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Eltrombopag Combining Rituximab Versus Eltrombopag in the Management of Primary Immune Thrombocytopenia (ITP) in Adults
Status: UNKNOWN
Conditions: Primary Immune Thrombocytopenia (ITP)
Interventions: DRUG: eltrombopag combining rituximab|DRUG: eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sildenafil for Cerebrovascular Dysfunction in Chronic Traumatic Brain Injury.
Status: COMPLETED
Conditions: Traumatic Brain Injury|Post-concussive Syndrome
Interventions: DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of YM155 Plus Docetaxel in Subjects With Stage III (Unresectable) or Stage IV Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: YM155|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lung Perfusion PET / CT Using Ga68-MAA for Preservation of Lung Function During Stereotactic Pulmonary Radiation Therapy
Status: UNKNOWN
Conditions: SBRT|Non-small Cell Lung Cancer|Lung Metastasis
Interventions: DRUG: Pre-therapeutic imaging test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Valproic Acid for Treatment of Hyperactive or Mixed Delirium in ICU
Status: TERMINATED
Conditions: Hyperactive Delirium|Mixed Delirium
Interventions: DRUG: Valproic Acid|DRUG: Placebo|DRUG: Haloperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Bioavailability Study of Lasolvan Hard Capsules and Effervescent Tablets in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lasolvan tablet|DRUG: Lasolvan tablet|DRUG: Lasolvan tablet|DRUG: Lasolvan tablet|DRUG: Lasolvan effervescent tablet|DRUG: Lasolvan effervescent tablet|DRUG: Lasolvan effervescent tablet|DRUG: Lasolvan prolonged-release hard capsule|DRUG: Lasolvan prolonged-release hard capsule|DRUG: Lasolvan prolonged-released capsules|DRUG: Lasolvan tablet|DRUG: Lasolvan tablet|DRUG: Lasolvan prolonged-release hard capsule|DRUG: Lasolvan effervescent tablet|DRUG: Lasolvan prolonged-release hard capsule|DRUG: Lasolvan prolonged-release hard capsule|DRUG: Lasolvan effervescent tablet|DRUG: Lasolvan effervescent tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Check-list Method for Nocturnal Enuresis
Status: COMPLETED
Conditions: Nocturnal Enuresis
Interventions: DRUG: desmopressin melt form 120 μg|BEHAVIORAL: Verbal behavioral therapy|BEHAVIORAL: Behavioral therapy with written check-list
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Subacromial Ultrasound-guided or Systemic Steroid Injection for Rotator Cuff Disease, a Randomized Double Blinded Study
Status: COMPLETED
Conditions: Rotator Cuff Disease
Interventions: DRUG: triamcinolone and lidocaine hydrochloride|DRUG: triamcinolone and lidocaine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmetomidine in Children Undergoing General Anaesthesia
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Dexmedetomidine|OTHER: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Bupivacaine-magnesium Combination Versus Bupivacaine Alone in Genicular Nerve Block
Status: NOT_YET_RECRUITING
Conditions: Post Operative Pain
Interventions: PROCEDURE: genicular nerve block using bupivacaine and magnesium|PROCEDURE: genicular nerve block using bupivacaine and normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Herpes Simplex Virus Type 2 (HSV-2) Therapeutic DNA Vaccine
Status: COMPLETED
Conditions: Herpes Genitalis
Interventions: BIOLOGICAL: VCL-HB01|OTHER: Phosphate-buffered saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of 120 mg Etoricoxib Film-coated Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Etoricoxib 120Mg Film-coated Tablet|DRUG: Arcoxia® 120 mg Film-coated tablet (Frosst Iberica S.A., Spain for Merck Sharp & Dohme (Australia) Pty Limited, Australia, registered by PT. Schering-Plough Indonesia Tbk)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Multidisciplinary Approach for Poor Prognosis Sinonasal Tumors in Operable Patients
Status: UNKNOWN
Conditions: Sinonasal Tumors
Interventions: DRUG: Cisplatin|DRUG: Docetaxel|DRUG: 5-fluorouracil|DRUG: Etoposide|DRUG: Adriamycin|DRUG: Ifosfamide|DRUG: Leucovorin|RADIATION: Radiotherapy - Patients needing Elective Nodal Volume (ENI)|RADIATION: Radiotherapy - Patients not needing ENI|RADIATION: Radiotherapy - Patients needing curative neck irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Automated Anesthesia Guided by the Conox Monitor for Surgery
Status: TERMINATED
Conditions: Anesthesia, General
Interventions: DEVICE: Closed loop anesthesia|DRUG: Propofol|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Project 1, Study 1: Investigating the Impact of Nicotine Using Spectrum Cigarettes
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: OTHER: very low nicotine content cigarettes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Alemtuzumab and Combination Chemotherapy Followed By Donor Lymphocytes in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: BIOLOGICAL: alemtuzumab|BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: fludarabine phosphate|DRUG: melphalan|DRUG: tacrolimus|DRUG: thiotepa|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The HALT Biomarker Study
Status: RECRUITING
Conditions: Aortic Stenosis|Hypo-attenuated Leaflet Thickening|Bioprosthetic Valve Degeneration
Interventions: DIAGNOSTIC_TEST: Proteomics Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Carglumic Acid in Methylmalonic Acidemia and Propionic Acidemia
Status: COMPLETED
Conditions: Propionic Acidemia|Methylmalonic Acidemia
Interventions: DRUG: Carglumic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic and Glucodynamic Study of Subcutaneously Administered Insulin Analogs With rHuPH20 Compared to Insulin Analogs Alone
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Recombinant human hyaluronidase PH20 (rHuPH20)|DRUG: Insulin lispro|DRUG: Insulin glulisine|DRUG: Insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Periodontally Accelerated Orthodontics - A Novel Technique For a Shortened Orthodontic Treatment With a Stable Result. A Clinical and Computerized Tomography Analysis
Status: UNKNOWN
Conditions: Periodontal Status of Patients Treated With PAO Tec
Interventions: PROCEDURE: PAO
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Atorvastatin on Endothelial Progenitor Cells After Coronary Surgery
Status: COMPLETED
Conditions: Coronary Artery Bypass Surgery|Elective Surgical Procedure
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Combine EMS and Mirror Therapy in Upper Limb Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: EMS, Mirror therapy & exercises|OTHER: CIMT & exercises|OTHER: Mirror therapy & exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of L-arginine and Liposomial Vitamin C on Severe Copd Patients Undergoing Pulmonary Rehabilitation.
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease|Respiratory Failure
Interventions: DIETARY_SUPPLEMENT: effect of L-arginine and liposomial vitamin C on pulmonary rehabilitation|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-inferiority of Portable Versus Desktop Spirometry
Status: COMPLETED
Conditions: Asthma|COPD
Interventions: DEVICE: AioCare|DEVICE: Spirometer USB CPFS/D (MGC Diagnostics)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 3 Efficacy and Safety Study of CD07805/47 Topical Gel in Subjects With Facial Erythema of Rosacea
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: Drug: CD07805/47 gel|DRUG: CD07805/47 gel Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sofosbuvir/Ledipasvir ± Ribavirin in Japanese Participants With Chronic Genotype 1 HCV Infection
Status: COMPLETED
Conditions: Chronic HCV Infection
Interventions: DRUG: LDV/SOF|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Dose Study of BMS-820132 in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Placebo|DRUG: Placebo|DRUG: BMS-820132|DRUG: BMS-820132|DRUG: BMS-820132|DRUG: BMS-820132|DRUG: BMS-820132|DRUG: BMS-820132|DRUG: BMS-820132
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Response to Different Wheat Genotypes in Not-celiac Wheat Sensitivity
Status: RECRUITING
Conditions: Non-celiac Wheat Sensitivity
Interventions: DIETARY_SUPPLEMENT: Wheat flour|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Reduction of Pro-Inflammatory Synovial Fluid Biomarkers in Osteoarthritis of the Knee With Alpha-2 Macroglobulin
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: BIOLOGICAL: synovial fluid biomarker concentrations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Management Following Musculoskeletal Injury
Status: COMPLETED
Conditions: Musculoskeletal Strain|Musculoskeletal Sprain|Injury of Musculoskeletal System
Interventions: BEHAVIORAL: Computer based pain management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Clinical Assessment of Fish Oil-based Lipid Emulsion Infusions in Critical Patients With Severe Sepsis
Status: COMPLETED
Conditions: Severe Sepsis
Interventions: DRUG: omega-3-fatty acids (Omegaven)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Cenicriviroc for the Treatment of Nonalcoholic Steatohepatitis (NASH) in Adult Participants With Liver Fibrosis
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: Cenicriviroc|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Validation of Rapid Detection of the COVID-19 Causative Virus (SARS-CoV-2) in Saliva Samples by Mass Spectrometry
Status: COMPLETED
Conditions: Covid19
Interventions: DIAGNOSTIC_TEST: Nasopharyngeal sampling|DIAGNOSTIC_TEST: Saliva sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Coffee and Hot Water on Gastroıntestınal Functıons
Status: COMPLETED
Conditions: COFFEE|Gastrointestinal Motility and Defecation Conditions
Interventions: OTHER: Coffee|OTHER: Hot water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Self-adhering Mesh and Conventional Mesh in Inguinal Hernia Repair.
Status: TERMINATED
Conditions: Inguinal Hernia
Interventions: PROCEDURE: Open anterior inguinal hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Promoting Successful Weight Loss in Primary Care in Louisiana Using Information Technology
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Diabetes Mellitus, Type 2|PreDiabetes
Interventions: BEHAVIORAL: Intensive Lifestyle Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anterior Segment Changes by Optical Coherence Tomography (OCT) in Phaco- Trabeculectomy
Status: UNKNOWN
Conditions: Angle Closure Glaucoma|Glaucoma|Cataract Secondary
Interventions: PROCEDURE: phaco- trabeculectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Saxagliptin as Monotherapy in Pediatric Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Saxagliptin|DRUG: Placebo (Saxagliptin)|DRUG: Metformin IR|DRUG: Placebo (Metformin)|DRUG: Metformin (Active Rescue)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of The Health Care CEO App for T1D
Status: UNKNOWN
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: Healthcare CEO app- for experimental app intervention|DEVICE: Healthcare CEO app-for control app intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Efficacy of Growth Hormone on Healing of Periapical Pathosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Periapical Diseases|Growth Hormone|Non Surgical Debulking
Interventions: PROCEDURE: Non surgical debulking of periapical tissues|PROCEDURE: Growth hormone application|PROCEDURE: Non surgical debulking of periapical tissues with growth hormone application|PROCEDURE: Root canal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Follow Up of Adult Patients Treated With Extracorporeal Membrane Oxygenation for Respiratory Failure
Status: COMPLETED
Conditions: Long Term Adverse Effects|Pneumonia|Acute Respiratory Distress Syndrome|Sepsis|Critical Illness|Cognitive Impairment|Extracorporeal Circulation; Complications
Interventions: RADIATION: High-resolution computed tomography|RADIATION: Magnetic resonance imaging|BEHAVIORAL: Cognitive testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of FMT Capsule Treating Steroid-refractory GI-aGvHD
Status: UNKNOWN
Conditions: Steroid-refractory Gastrointestinal Acute Graft Versus Host Disease
Interventions: BIOLOGICAL: Fecal Microbiota Transplant (FMT) Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain and Trismus Control in Third Molar Surgery: Ibuprofen, Ketamine, and Their Combination
Status: RECRUITING
Conditions: Molar, Third
Interventions: PROCEDURE: Impacted third molar surgey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact Of Physiotherapy And Botox In Improving Functional Outcomes Among Post Stroke Focal Dystonia Patients
Status: COMPLETED
Conditions: Focal Hand Dystonia
Interventions: OTHER: Botulinum toxin type A|OTHER: Task Specific Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Massage for the Treatment of Cancer-Related Fatigue (CRF) in Prostate Cancer Survivors
Status: COMPLETED
Conditions: Cancer-related Problem/Condition
Interventions: OTHER: Swedish Massage Therapy|OTHER: Light Touch Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioequivalence Study of Paroxetine Tablets and Paxil® Under Fasting and Fed Conditions in Chinese Healthy Volunteers
Status: COMPLETED
Conditions: Major Depressive Disorder|Obsessive-Compulsive Disorder|Panic Disorder|Social Anxiety Disorder|Generalized Anxiety Disorder
Interventions: DRUG: Paroxetine Hydrochloride Tablet 20 mg|DRUG: Paxil® 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cutibacterium Acnes: Triple Prevention in Shoulder Operations
Status: RECRUITING
Conditions: Post-Operative Wound Infection|Surgical Site Infection
Interventions: PROCEDURE: Subcutaneous disinfection|PROCEDURE: Benzoyl peroxide preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Pharmacokinetic, Pharmacodynamic, Safety and Efficacy Study of Three Anti-CD20 Monoclonal Antibodies in Patients With Moderate to Severe Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: DRL_RI|BIOLOGICAL: Rituxan|BIOLOGICAL: MabThera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of Heart Rate Variability After a Physical Exercise Session
Status: RECRUITING
Conditions: Hypertension
Interventions: OTHER: Aerobic Exercise. 1 session of acute exercise|OTHER: Resistance Exercise. 1 session of acute exercise|OTHER: no exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH