pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety of JS016 in Patients With SARS-CoV-2 Infection (COVID-19)
Status: UNKNOWN
Conditions: COVID-19|SARS-CoV-2
Interventions: DRUG: JS016
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intracameral Cefuroxime on Post-op Fibrin in Pediatric Cataract Surgery
Status: COMPLETED
Conditions: Cataract|Endophthalmitis
Interventions: DRUG: cefuroxime|DRUG: Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Clinical Trial of Efficacy and Safety of BCD-055 and Remicade® in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: BCD-055|BIOLOGICAL: Remicade®|DRUG: Methotrexate|DRUG: Folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dociparstat Sodium (CX-01) Combined With Standard Induction Therapy for Newly Diagnosed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Dociparstat sodium|DRUG: Idarubicin|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies
Status: NOT_YET_RECRUITING
Conditions: Chronic Lymphocytic Leukaemia|Small Lymphocytic Leukaemia|Mantle-cell Lymphoma|Large B-cell Lymphoma|B-cell Non-Hodgkin Lymphoma
Interventions: DRUG: AZD0486|DRUG: Acalabrutinib|DRUG: Prednisone|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Vincristine|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Serum Levels of Interlukin-15 and Interlukin-21 in Patients With Alopecia Areata
Status: NOT_YET_RECRUITING
Conditions: Alopecia Areata
Interventions: DIAGNOSTIC_TEST: Serum Interlukin-15|DIAGNOSTIC_TEST: Serum Interlukin-21
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety/Efficacy of Q-122 in Breast Cancer Patients Taking Tamoxifen or Aromatase Inhibitor
Status: COMPLETED
Conditions: Vasomotor Symptoms (VMS)
Interventions: DRUG: Q-122|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic Sarcomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcoma|Advanced Sarcoma|High Grade Sarcoma|Leiomyosarcoma|Undifferentiated Pleomorphic Sarcoma|Myxofibrosarcoma|Dedifferentiated Liposarcoma
Interventions: DRUG: DCC-3014|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapamycin Treatment for ALS
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Rapamycin|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endothelial Microparticules and Antibody Mediated Rejection and Kidney Transplantation: Biomarker of Antibody-mediated Rejection in Kidney Transplantation
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: BIOLOGICAL: Biological sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Tolerability and Pharmacokinetic of Recombinant Anti-IL-5 Humanized Monoclonal Antibody Injection
Status: UNKNOWN
Conditions: add-on Maintenance Treatment of Patients With Severe Eosinophilic Asthma
Interventions: DRUG: 610|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Screening Strategies for Gestational Diabetes (GDM2)
Status: COMPLETED
Conditions: Gestational Diabetes|Pregnancy|Glucose Intolerance
Interventions: DIAGNOSTIC_TEST: Gestational diabetes screening with fasting 3 hour 100 gm|DIAGNOSTIC_TEST: Gestational diabetes screening with fasting 2 hour 75g
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Effect of Low-level Laser Therapy Versus Shock Wave Therapy on Pain and Function in Patients With Chronic Non-specific Low Back Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Low Back Pain
Interventions: OTHER: Low-level laser therapy|OTHER: Shock wave Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Serotonin Inhibitors on Patient-controlled Analgesia Related Nausea and Vomiting
Status: COMPLETED
Conditions: Agitation
Interventions: BEHAVIORAL: agitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Into the Effect of Seprafilm in Open Total Thyroidectomy
Status: TERMINATED
Conditions: Thyroid Carcinoma
Interventions: DEVICE: Seprafilm (Sanofi, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of ARQ 197 in Healthy Volunteers to Assess the Pharmacokinetic (PK) Profile in Extensive and Poor Metabolizers as Defined by Cytochrome P450 2C19 (CYP 2C19) Genotype
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Treatment with ARQ 197
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Daily Adaptive Post-Prostatectomy With Stereotactic Ablative Radiotherapy in Patients With Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Prostate Neoplasm
Interventions: PROCEDURE: Computed Tomography|RADIATION: Image-Guided Adaptive Radiation Therapy|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|OTHER: Questionnaire Administration|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial Photodynamic Therapy in Treatment of Aggressive Periodontitis (Stage III, Grade C Periodontitis)
Status: COMPLETED
Conditions: Aggressive Periodontitis
Interventions: DEVICE: antimicrobial photodynamic therapy|DRUG: systemic antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Trauma and Violence in the Townships of South Africa
Status: COMPLETED
Conditions: Post-traumatic Stress Disorder (PTSD)|Aggressive Behavior
Interventions: BEHAVIORAL: FORNET|BEHAVIORAL: CBT|OTHER: Waiting List Control Group (camp)|OTHER: Waiting List Control Group (no camp)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Control Trial of Micronized Purified Flavonoid Fraction for Post Operative Treatment in Anal Fistula Surgery
Status: RECRUITING
Conditions: Anal Fistula
Interventions: DRUG: Micronized purified flavonoid fraction(Daflon 1000mg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Different Flap Designs for Bilateral Impacted Mandibular Third Molar Surgery
Status: COMPLETED
Conditions: Impacted Third Molar Tooth
Interventions: PROCEDURE: lingually-based triangle flap design|OTHER: buccally based triangular flap design
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexmedetomidine on Microcirculation in Patients Undergoing Extracorporeal Shock Wave Lithotripsy
Status: WITHDRAWN
Conditions: Microcirculation
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Postoperative Nudges to Reduce Opioid Prescribing
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid Prescribing
Interventions: BEHAVIORAL: Guideline-Based (Injunctive Norm) Nudges|BEHAVIORAL: Peer-Based (Social Norm) Nudges
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Best Treatment Choice for Osteonecrosis of the Jaw
Status: RECRUITING
Conditions: Medication Related Osteonecrosis of the Jaw
Interventions: DRUG: Antibiotics|DRUG: Chlorhexidine mouthwash|PROCEDURE: Minimally invasive surgery with LPRF|PROCEDURE: Surgical resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Of Probiotics vs. Zinc vs. Probiotics-Zinc Combination On Acute Diarrhea In Children
Status: COMPLETED
Conditions: Acute Diarrhea
Interventions: OTHER: Probiotics|OTHER: Zinc|OTHER: Probiotics & Zinc|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Provider Supported Self-Help Cognitive Behavioral Therapy for Insomnia (Tele-Self CBTI)
Status: COMPLETED
Conditions: Insomnia Disorder
Interventions: BEHAVIORAL: Tele-Self CBTI|OTHER: Health Education Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Open Label Study Assessing the 24-hour Intraocular Pressure Pattern in PAC and PACG Patients, Before and After Laser Peripheral Iridotomy
Status: COMPLETED
Conditions: Glaucoma
Interventions: DEVICE: SENSIMED Triggerfish®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Chronic Pain Master Protocol (CPMP): A Study of LY3556050 in Participants With Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: LY3556050|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Synbiotics Supplement on Lipid Profile, Liver Enzymes, Inflammatory Factors and Hepatic Fibrosis in Lean and Normal Weight Patients With Nonalcoholic Fatty Liver
Status: UNKNOWN
Conditions: Non Alcoholic Steatohepatitis
Interventions: DIETARY_SUPPLEMENT: synbiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Followed By Donor Bone Marrow or Umbilical Cord Blood Transplant in Treating Children With Newly Diagnosed Juvenile Myelomonocytic Leukemia
Status: COMPLETED
Conditions: Juvenile Myelomonocytic Leukemia
Interventions: DRUG: tipifarnib|DRUG: isotretinoin|DRUG: fludarabine phosphate|DRUG: cytarabine|RADIATION: radiation therapy|DRUG: cyclophosphamide|BIOLOGICAL: anti-thymocyte globulin|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: double-unit umbilical cord blood transplantation|PROCEDURE: umbilical cord blood transplantation|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of VX-548 for Painful Diabetic Peripheral Neuropathy (DPN)
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy
Interventions: DRUG: VX-548|DRUG: Pregabalin|DRUG: Placebo (matched to VX-548)|DRUG: Placebo (matched to pregabalin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kinematic Alignment vs Mechanical Alignment for Total Knee Arthroplasty
Status: WITHDRAWN
Conditions: Knee Osteoarthritis|Knee Pain Chronic
Interventions: PROCEDURE: Mechanical Alignment and Unrestricted Kinematic Alignment using Medacta GMK Sphere with MyKnee Custom guides|PROCEDURE: Mechanical Alignment and Restricted Kinematic Alignment using Medacta GMK Sphere with custom cutting guides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Segmental Breathing Exercise in Patients Awaiting Coronary Artery Bypass Graft Surgery (CABG)
Status: COMPLETED
Conditions: Complications Due to Coronary Artery Bypass Graft
Interventions: OTHER: segmental breathing exercise|OTHER: deep breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Assess the Combination of Two Drugs (177Lu-DOTATATE and Nivolumab) in Neuroendocrine Tumours
Status: RECRUITING
Conditions: Neuroendocrine Tumours (NET)|Neuroendocrine Carcinomas (NEC)
Interventions: DRUG: 177Lu-Dotatate|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mind Body Intervention for Long COVID-19
Status: RECRUITING
Conditions: Long COVID|Post-Acute Sequelae of COVID-19|COVID Long-Haul
Interventions: BEHAVIORAL: Mind Body Intervention #1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vascular Endothelial Growth Factor (VEGF) Imaging Before and During Everolimus Treatment for Renal Cell Carcinoma
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: OTHER: 89Zr-bevacizumab PET scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rapid Molecular Organism Identification and Mixed Flora Antibiotic Resistance Profiling (MixAR) Prospective Study
Status: COMPLETED
Conditions: Urinary Tract Infections|Prostatitis|Interstitial Cystitis
Interventions: DIAGNOSTIC_TEST: Guidance 4.0 PCR test|DIAGNOSTIC_TEST: Urine Culture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: This Study is to Determine if Degenerative Spinal Pain and Disorders Cause the Levels of Substance P to Change in a Patients Saliva, Blood and/or Cerebrospinal Fluid.
Status: TERMINATED
Conditions: Spinal Disease|Spinal Radiculopathy|Myelopathy|Neurogenic Claudication
Interventions: OTHER: treatment plan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Continuous Cardiac Monitoring to Assess Atrial Fibrillation After Cryptogenic Stroke
Status: COMPLETED
Conditions: Cryptogenic Symptomatic Transient Ischemic Attack|Cryptogenic Ischemic Stroke
Interventions: DEVICE: Reveal® XT Insertable Cardiac Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Determining The Effects Of Nasopharyngeal Suction
Status: COMPLETED
Conditions: Aspiration, Respiratory|Pain|Mucosal Irritation|Infant
Interventions: DEVICE: Experimental group|DEVICE: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Proximal Interphalangeal Joint Arthroplasty Using a Graft From the Capitate
Status: COMPLETED
Conditions: Recurrent Dislocation of Hand
Interventions: PROCEDURE: Capitate bone grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of Manual Dexterity by Finger Force Manipuladum (FFM) in Patients With Writer's Cramp and in Control Subjects
Status: COMPLETED
Conditions: Dystonic Disorder|Focal Dystonia|Writer's Cramp
Interventions: DEVICE: Finger Force Manipuladum (FFM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Assessment of Alcon's Ocular Image Quantification System
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Olopatadine hydrochloride, 0.1% ophthalmic solution (Patanol)|OTHER: Dextran 70 0.1%, hydroxypropyl methylcellulose 0.3% (Tears Naturale II)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Topical Vitamin K, Vitamin K and Retinol, and Arnica on Post-Laser Bruising
Status: COMPLETED
Conditions: Ecchymosis
Interventions: DRUG: Petrolatum United States Pharmacopeia (USP)|DRUG: Vitamin K and retinol ointment|DRUG: Arnica ointment|DRUG: Vitamin K ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Self-administered Acupressure for Insomnia Disorder
Status: COMPLETED
Conditions: Insomnia Chronic
Interventions: BEHAVIORAL: Self-administered acupressure group|BEHAVIORAL: Sleep hygiene education (SHE) group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RAT and FES Effects on Upper Limb Motor Function in Subacute Stroke Patients
Status: NOT_YET_RECRUITING
Conditions: Motor Function
Interventions: DEVICE: Functional Electrical Stimulation|DEVICE: Hand Robotic-Assisted Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study to Evaluate the Long-Term Safety of ThermoProfen™ in Patients With Mild to Moderate Pain Associated With Osteoarthritis of the Knee.
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: DRUG: ThermoProfen™ (Matrix Transdermal Ketoprofen/CHADD™ System)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label Study of the Effects of Elagolix in Adult Premenopausal Females
Status: COMPLETED
Conditions: Folliculogenesis
Interventions: DRUG: Elagolix|DRUG: Elagolix|DRUG: Elagolix|DRUG: Elagolix|DRUG: Elagolix|DRUG: Elagolix|DRUG: elagolix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Endothelial Function as a Marker for Blood Pressure Control Among Hypertensive Diabetic Patients
Status: COMPLETED
Conditions: Hypertension|Diabetes Mellitus Type 2
Interventions: DRUG: N-acetylcystein(drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Alleviating Persistent Dyspnea in Amyotrophic Lateral Sclerosis Patients Treated With Non-Invasive Ventilation Through Immersive Virtual Reality
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DEVICE: Immersive virtual reality (IVR) & Music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of VR-ESMEPP on Parents' Seizure Management
Status: COMPLETED
Conditions: Virtual Reality|Epilepsy|Seizure|Child|Nurse|Parents
Interventions: BEHAVIORAL: Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Platelet-rich Fibrin on Nerve Regeneration After Bilateral Sagittal Split Osteotomy
Status: UNKNOWN
Conditions: Paresthesia|Anesthesia, Local|Neurosensory Disorder
Interventions: BIOLOGICAL: Platelet rich fibrin|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Framing Clinical Trial Enrollment for Patients With Peripheral Artery Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Artery Disease
Interventions: BEHAVIORAL: Opt-out
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Assessment of Bone Quality After Socket Preservation Using Sodium Alendronate Gel Compared to Sticky Bone
Status: RECRUITING
Conditions: Bone Quality Assessment|Preserved Sockets|Sodium Alendronate|Sticky Bone
Interventions: PROCEDURE: socket preservation using sodium alendronate gel|PROCEDURE: socket preservation using sticky bone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The PREBA Study: Effect of Preoperative Weight Loss With a 14-day Low-calorie Diet on Surgical Procedure and Outcomes in Patients Undergoing RYGB Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Bariatric Surgery|Morbid Obesity
Interventions: OTHER: 14-day Low Calorie Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Personalized Repetitive Transcranial Magnetic Stimulation Protocol Based on Functional Reserve to Enhance Upper Limb Function in Subacute Stroke Patients
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: High-Frequency1|DEVICE: cTBS1|DEVICE: High-Frequency2|DEVICE: cTBS2|DEVICE: High-Frequency3|DEVICE: cTBS3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sensory Stimulation Effect on Movement Speed in Patients With Parkinson Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: OTHER: Aponeurotic stimulation (the diacutaneous fibrolysis method)|OTHER: Placebo stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Application of tDCS Stimulation in Controlling Refractory Status Epilepticus
Status: RECRUITING
Conditions: Refractory Status Epilepticus
Interventions: DEVICE: tDCS stimulation|DEVICE: TDCS sham-stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: 20-valent Pneumococcal Conjugate Vaccine Safety and Immunogenicity Study in Healthy Japanese Infants
Status: COMPLETED
Conditions: Pneumococcal Disease
Interventions: BIOLOGICAL: 20-valent pneumococcal conjugate vaccine|BIOLOGICAL: 13-valent pneumococcal conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and Efficacy of Everolimus, in Subjects With PIK3CA Amplification, PTEN Loss and PIK3CA Mutation Refractory Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics in Respiratory Tract Infections in Children
Status: COMPLETED
Conditions: Infections, Respiratory Tract
Interventions: DIETARY_SUPPLEMENT: L. acidophilus DDS-1, B. lactis UABLA-12|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Spinal Stimulation Sit-to-Stand Training After Spinal Cord Injury
Status: TERMINATED
Conditions: Spinal Cord Injuries
Interventions: OTHER: Spinal Stimulation|OTHER: Sit-to-stand Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of a Single Dose of 5 mg of hLF1-11 Given to Autologous Haematopoietic Stem Cell Transplant Recipients
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplantation|Bacterial Infections and Mycoses
Interventions: DRUG: human lactoferrin peptide 1-11
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Goal-directed Therapy in High-risk Surgery
Status: UNKNOWN
Conditions: Perioperative/Postoperative Complications|Hypovolemia|Hypoxia
Interventions: PROCEDURE: Protocol group 2|PROCEDURE: Protocol group 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CLEAR SYNERGY Neutrophil Substudy
Status: ACTIVE_NOT_RECRUITING
Conditions: Neutrophils.Hypersegmented &#X7C; Bld-Ser-Plas|STEMI - ST Elevation Myocardial Infarction
Interventions: DRUG: Colchicine Pill
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Benefits of GIK in Cardiac Surgery Patients
Status: UNKNOWN
Conditions: Cardiac Surgery|Cardiopulmonary Bypass
Interventions: DRUG: GIK|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Evaluating the Pan-vascular Interventional Robotic System for Panvascularization Interventional Surgery
Status: NOT_YET_RECRUITING
Conditions: Percutaneous Coronary Intervention
Interventions: DEVICE: Pan-vascular interventional robotic system|PROCEDURE: Traditional artificial percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dopamine vs. Norepinephrine for Hypotension in Very Preterm Infants With Late-onset Sepsis
Status: RECRUITING
Conditions: Late-Onset Neonatal Sepsis|Extreme Prematurity|Neonatal Hypotension
Interventions: DRUG: Dopamine|DRUG: Norepinephrine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Nursing Follow-Up by Phone on The Self-Efficacy,Pain,Disease Activity in Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Tele-nursing
Interventions: BEHAVIORAL: NURSING FOLLOW-UP BY PHONE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mesenchymal Stemcells for Radiation Induced Xerostomia
Status: COMPLETED
Conditions: Xerostomia
Interventions: DRUG: Mesenchymal stem cell|DRUG: Isotonic NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduced Toxicity Conditioning Prior to Unrelated Cord Cell Transplantation for High Risk Myeloid Malignancies
Status: UNKNOWN
Conditions: Leukemia, Myeloid
Interventions: DRUG: IV Thiotepa|DRUG: IV Fludarabine|DRUG: IV Busulfan|DRUG: IV Anti-thymocyte globuline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Dapivirine Vaginal Ring (VR) in Adolescents
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: COMBINATION_PRODUCT: placebo ring|COMBINATION_PRODUCT: dapivirine ring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase III Study of Abatacept in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Abatacept|DRUG: Methotrexate|DRUG: Placebo|DRUG: Abatacept|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Learning Signature for Predicting Aggressive Histological Pattern in Resected Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|Spread Through Air Space|Visceral Pleural Invasion|Lymphovascular Invasion
Interventions: DIAGNOSTIC_TEST: PET/CT-based Deep Learning Signature
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Meta-Iodobenzylguanidine (123I-mIBG) Scintigraphy Imaging in Patients With Heart Failure and Control Subjects Without Cardiovascular Disease
Status: COMPLETED
Conditions: Heart Failure, Congestive
Interventions: DRUG: 123I-mIBG (meta-iodobenzylguanidine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Diabetic Foot Ulcer (DFU) Rapid Pathogen Identification
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot Ulcer|Diabetes Mellitus|Wound
Interventions: DIAGNOSTIC_TEST: Conventional bacterial culture|DEVICE: Rapid diagnostic group using mNGS technology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Exercise Intervention Using mHealth in Patients With Post-Acute COVID-19 Syndrome: a Randomized Clinical Trial
Status: RECRUITING
Conditions: Post-Acute COVID19 Syndrome|Long COVID|Post COVID-19 Condition
Interventions: DEVICE: COVIDReApp Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Cranial Internal Carotid Artery Aneurysm With Willis Covered Stent and Coil Embolization
Status: UNKNOWN
Conditions: Intracranial Aneurysms
Interventions: PROCEDURE: Covered stent|PROCEDURE: Coil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Duloxetine 60 mg With Regards to Reference Product in Fasting Conditions
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Duloxetine 60mg Test Drug Enteric Coated Granules|DRUG: Duloxetine 60mg Reference Product Enteric Coated Granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transition of T1DM Patients Aged Over 65 Years Into AHCL (780G) Insulin Pump
Status: ENROLLING_BY_INVITATION
Conditions: Diabetes Type 1
Interventions: DEVICE: MiniMed 780G system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Baricitinib for the Prophylaxis of Graft-Versus-Host Disease After Peripheral Blood Hematopoietic Cell Transplantation
Status: COMPLETED
Conditions: Graft-versus-host-disease|Graft Vs Host Disease
Interventions: DRUG: Baricitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nebulized or Inhaled Albuterol for Lymphangioleiomyomatosis
Status: RECRUITING
Conditions: Lymphangioleiomyomatosis
Interventions: DRUG: albuterol inhaler|DRUG: albuterol nebulizer|PROCEDURE: PFT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biological Bank for the Patients Followed in a Constitutive Reference Center for Autoimmune Cytopenia
Status: RECRUITING
Conditions: Immune Thrombocytopenia|Autoimmune Hemolytic Anemia|Autoimmune Neutropenia
Interventions: BIOLOGICAL: blood sample|BIOLOGICAL: urine sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Colloid (20% Albumin) Versus Crystalloid (Plasmalyte) for Fluid Resuscitation in Cirrhotics With Sepsis Induced Hypotension.
Status: COMPLETED
Conditions: Cirrhosis With Sepsis
Interventions: BIOLOGICAL: 20% Albumin|OTHER: Plasmalyte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amoxicillin to Prevent Bacteria and Inflammatory Biomarkers After Intensive Periodontal Therapy
Status: UNKNOWN
Conditions: Chronic Periodontitis|Bacteremia
Interventions: DRUG: Amoxicillin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Weightbearing and Mobilization Versus Non-Weightbearing and Mobilization in Unstable Ankle Fractures
Status: UNKNOWN
Conditions: Ankle Injuries
Interventions: BEHAVIORAL: Early weight-bearing and range of motion exercises|BEHAVIORAL: non-weight bearing, no range of motion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Profiles in Multiple Sclerosis (MS) Patients and Healthy Volunteers Through Thoracic Duct Cannulation
Status: ENROLLING_BY_INVITATION
Conditions: Multiple Sclerosis|Healthy
Interventions: PROCEDURE: thoracic duct cannulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Predicting the Impact of Treatment Toxicities on Health During Cancer ( PATTERN )
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: PROCEDURE: Assessment of Therapy Complications|OTHER: Electronic Health Record Review|OTHER: Medical Device Usage and Evaluation|OTHER: Medical Device Usage and Evaluation|OTHER: Survey Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sleep Quality in Pregnancy and Its Impact on Pregnancy Outcomes
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea|Pregnancy Induced Hypertension|High-Risk Pregnancy|Restless Leg Syndrome|Infant, Very Low Birth Weight
Interventions: OTHER: Polysomnography and ambulatory blood pressure recording
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: To Evaluate the Performance of Total 30 (Lehifilcon A) Contact Lenses in Patients Using Digital Devices for Greater Than 8 Hours Per Day 5 Days Per Week Based on Subjective Reported Data.
Status: NOT_YET_RECRUITING
Conditions: Eye Strain
Interventions: DEVICE: Total 30 Contact Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Effectiveness of Combretastatin A-4 Phosphate Combined With Chemotherapy in Advanced Solid Tumors
Status: COMPLETED
Conditions: Cancer|Tumor
Interventions: DRUG: Combretastatin A-4 Phosphate + Paclitaxel + Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics for Depression in Cancer Patients
Status: RECRUITING
Conditions: Depression|Anxiety Disorder|Probiotics|Gastrointestinal Cancer|Quality of Life|Chemotherapy
Interventions: DIETARY_SUPPLEMENT: Psychobiotics|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Enhanced Perioperative Mobilization (EPM) Trial
Status: COMPLETED
Conditions: Pancreatic Resection|Liver Resection|Gastric Resection|Colorectal Resection
Interventions: DEVICE: activity tracking for autofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Hachi Barie" Project - A Multidisciplinary Program to Accompany Severely Obese Teenagers in the Weight Loss Process for the Benefit of Their Recruitment Into the Israel Defense Forces
Status: RECRUITING
Conditions: Morbid Obesity
Interventions: BEHAVIORAL: # The importance of service in the IDF # Physical activity # Healthy nutrition # Psychological support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Effect of Mobile Medical Used for the Standardized Management of Gestational Diabetes
Status: UNKNOWN
Conditions: GDM|Blood Glucose|Compliance, Patient|Diet Habit
Interventions: BEHAVIORAL: m-health management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Combination of Hypofractionated Radiotherapy and Immunotherapy in Locally Recurrent Rectal Cancer
Status: RECRUITING
Conditions: Recurrent Rectal Cancer
Interventions: DRUG: PD-1 antibody|DRUG: Capecitabine|DRUG: 5FU|DRUG: folinic acid|DRUG: Oxaliplatin|DRUG: Irinotecan|DRUG: Raltitrexed|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Craniomaxillofacial and Upper Extremity Allotransplantation
Status: RECRUITING
Conditions: Face Injuries|Hand Injuries|Craniofacial Injuries|Upper Extremity Injuries|Facial Injuries|Facial Deformity
Interventions: PROCEDURE: Combined Craniomaxillofacial and Upper Extremity Allotransplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interstitial Photodynamic Therapy Following Palliative Radiotherapy in Treating Patients With Inoperable Malignant Central Airway Obstruction
Status: NOT_YET_RECRUITING
Conditions: Malignant Solid Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Endobronchial Ultrasound Bronchoscopy|PROCEDURE: Interstitial Photodynamic Therapy|RADIATION: Palliative Radiation Therapy|OTHER: Physical Performance Testing|OTHER: Questionnaire Administration|DRUG: Verteporfin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CYP-001 in Combination With Corticosteroids in Adults With High-risk aGvHD
Status: RECRUITING
Conditions: Graft Versus Host Disease, Acute
Interventions: BIOLOGICAL: CYP-001: Cymerus induced pluripotent stem cell (iPSC)-derived mesenchymal stem cells (MSCs)|BIOLOGICAL: Placebo|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liver Cirrhosis Diagnosis Prioritizing Algorithm Based on Electronic Health Records.
Status: UNKNOWN
Conditions: NAFLD - Nonalcoholic Fatty Liver Disease|Fibrosis, Liver|Cirrhosis, Liver
Interventions: DIAGNOSTIC_TEST: Fibroscan (non interventional)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multi-center Trial of Revlimid® and Rituximab, for First-Line Treatment of Chronic Lymphocytic Leukemia (CLL)
Status: UNKNOWN
Conditions: Chronic Lymphocytic Leukemia|CLL|Untreated|Front-line|First-Line|Initial Therapy
Interventions: DRUG: Lenalidomide and Rituximab|DRUG: Lenalidomide and Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of AADvac1, a Tau Peptide-KLH-Conjugate Active Vaccine to Treat Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: BIOLOGICAL: AADvac1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of memanTine in the Treatment Of Frequently symPtomatic Atrial Premature Beats
Status: NOT_YET_RECRUITING
Conditions: Atrial Premature Beats, Contractions, or Systoles
Interventions: DRUG: Memantine Hydrochloride 10 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Decreasing Depression and Anxiety and Their Effect on QoL of ESRD Patients (End-Stage Renal Disease)
Status: UNKNOWN
Conditions: End-Stage Renal Disease
Interventions: BEHAVIORAL: CBI and Resilience|BEHAVIORAL: Cognitive-behavioral Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Precision Medicine for Nociception, Sngception and Proprioception.
Status: RECRUITING
Conditions: Rehabilitation|Pain, Shoulder|Pain, Chronic|Idiopathic Scoliosis
Interventions: DEVICE: LASER|DEVICE: Ultrasound|DRUG: Prolotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Advanced Breast Cancer|Metastatic Breast Cancer|ER Positive Breast Cancer|HER2 Negative Breast Carcinoma
Interventions: DRUG: Palazestrant|DRUG: Fulvestrant|DRUG: Anastrozole|DRUG: Letrozole|DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study of SPL7013 Gel (VivaGel) for the Treatment of Bacterial Vaginosis
Status: COMPLETED
Conditions: Bacterial Vaginosis
Interventions: DRUG: 1% SPL7013 Gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Flavanols in Exercise and Aging
Status: COMPLETED
Conditions: Aging
Interventions: DIETARY_SUPPLEMENT: High Flavanol Trial|DIETARY_SUPPLEMENT: Low Flavanol Trial|DIETARY_SUPPLEMENT: High Flavanol Trial; long-term|DIETARY_SUPPLEMENT: Low Flavanol Trial; long-term effects
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of FTY720 in Patients With Relapsing Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: FTY720|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Vinflunine Plus Gemcitabine Versus Paclitaxel Plus Gemcitabine in Patients With Advanced Breast Cancer
Status: TERMINATED
Conditions: Advanced Breast Cancer
Interventions: DRUG: Vinflunine+Gemcitabine|DRUG: Paclitaxel+Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Dopamine Transporter Receptor Occupancy With Long-acting Dex-methylphenidate
Status: COMPLETED
Conditions: Drug Binding to DAT Receptors
Interventions: DRUG: dex-methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Where's the Wif? Referent Selection and Retention
Status: RECRUITING
Conditions: Healthy
Interventions: BEHAVIORAL: Modality - 3D-2D|BEHAVIORAL: Modality - 2D-3D|BEHAVIORAL: Modality - 2D-2D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cerebril™ in Patients With Lobar Hemorrhage Related to Cerebral Amyloid Angiopathy
Status: COMPLETED
Conditions: Stroke|Neurologic Diseases, General
Interventions: DRUG: NC-758 (Anti amyloidotic [Aß] agent)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study Investigating the Efficacy of Crenolanib With Chemotherapy vs Chemotherapy Alone in R/R FLT3 Mutated AML
Status: RECRUITING
Conditions: Relapsed/Refractory Acute Myeloid Leukemia With FLT3 Activating Mutations
Interventions: DRUG: Crenolanib|DRUG: Cytarabine|DRUG: Mitoxantrone|DRUG: Placebo Oral Tablet|DRUG: Fludarabine|DRUG: Idarubicin|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between 6 Minute Walk Test, 6 Minute Step Test and 4 Metre Gait Speed
Status: COMPLETED
Conditions: Healthy|Children
Interventions: OTHER: 6 minutes walking test|OTHER: 6 minutes step test|OTHER: 4 meters gait speed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Everolimus as Inhibitor of Fibrosis Progression in Liver Transplant Patients With Recurrence of Hepatitis C Viral Infection
Status: TERMINATED
Conditions: Recurrent Hepatitis C
Interventions: DRUG: CsA-TAC (standard Treatment)|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT