pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Randomised, Double-blind, Phase I/II Study to Evaluate the PK, PD, Safety, and Efficacy Between HLX01 and Rituximab in Patients With Moderate to Severe Rheumatoid Arthritis and Inadequate Response to Treatment With DMARDs
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: HLX01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety and Pharmacodynamics of Repeat Intranasal Administration of the TLR7 Agonist GSK2245035 in Subjects With Respiratory Allergies
Status: COMPLETED
Conditions: Asthma and Rhinitis
Interventions: DRUG: GSK2245035|DEVICE: Type 1 amber glass bottle|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single-dose Study of [14C]PF-05221304 Metabolism and Excretion in Healthy Adult Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [14C]PF-05221304
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Injectable Beta-tricalcium Phosphate Clinically in Treatment of Grade II Furcation Involvement
Status: COMPLETED
Conditions: Furcation Defects
Interventions: OTHER: PD VitalOs cement®|OTHER: Hydroxyapatite bone graft|OTHER: biodegardable collagen membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Best Approach for Blocking Intercostobrachial and Medial Brachial Cutaneous Nerves in the Upper Arm Surgery
Status: RECRUITING
Conditions: Pain
Interventions: PROCEDURE: axillary brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 5500/20 vs. SABR or Brachytherapy for PRimary OligoMetastatic Prostate Cancer Treatment (PROMPT)
Status: RECRUITING
Conditions: Oligometastatic Prostate Cancer
Interventions: RADIATION: Hypofractionated external beam radiotherapy|RADIATION: High dose rate brachytherapy|RADIATION: Permanent seed implant|RADIATION: Stereotactic body radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Gabapentin on Cardiac Repolarization in Healthy Volunteers
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: GEn 1200mg|DRUG: Gen 6000 mg|DRUG: GEn Placebo|DRUG: Moxifloxacin Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Pharmacokinetic Study of Inhaled Esketamine in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Esketamine DPI|DRUG: Esketamine DPI|DRUG: Esketamine DPI|DRUG: Placebo DPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Elarekibep in Healthy Japanese Subjects
Status: TERMINATED
Conditions: Healthy Subjects (Indication: Asthma)
Interventions: DRUG: Elarekibep|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Grapiprant and Pembrolizumab in Patients With Advanced or Progressive MSS Colorectal Cancer
Status: COMPLETED
Conditions: Microsatellite Stable Colorectal Cancer
Interventions: DRUG: grapiprant|DRUG: grapiprant and pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Nesvacumab (REGN910/ SAR307746)
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: nesvacumab (REGN910/ SAR307746)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing a Novel Speech Intervention in Minimally Verbal Children With Autism Spectrum Disorder (ASD)
Status: COMPLETED
Conditions: Autism
Interventions: BEHAVIORAL: Auditory-Motor Mapping Training|BEHAVIORAL: Speech-Repetition Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy
Status: COMPLETED
Conditions: Acute Pain|Atrophic|Goals|Impairment|Infiltration|Injury|Muscle Weakness|Pain|Pathology|Shoulder Pain|Syndrome|Tendinopathy
Interventions: PROCEDURE: Subacromial injection|OTHER: Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Mobilization With Movement on Weight Bearing Ankle Dorsiflexion Range of Motion
Status: RECRUITING
Conditions: Ankle Joint Contracture
Interventions: PROCEDURE: Mobilization with movement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of NGX-4010 for the Treatment of Painful HIV-Associated Neuropathy
Status: COMPLETED
Conditions: Pain|HIV Infections|Peripheral Nervous System Diseases
Interventions: DRUG: NGX-4010, 8% capsaicin patch|DRUG: 0.04% capsaicin patch|DRUG: NGX-4010, 8% capsaicin patch|DRUG: 0.04% capsaicin patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes of NOSES Versus Traditional Robotic-assisted Surgery for Patients With Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Neoplasms|Neoplasms Malignant|Complication of Surgical Procedure|Robotic Surgical Procedures|Natural Orifice Specimen Extraction Surgery
Interventions: PROCEDURE: Natural Orifice Specimen Extraction Surgery|PROCEDURE: Traditional Robotic-assisted Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optical Coherence Tomography Quantitative Analysis of Changes in Anterior Chamber After Laser Peripheral Lridotomy
Status: UNKNOWN
Conditions: Primary Angle Closure Glaucoma
Interventions: PROCEDURE: Laserex Tango Nd:YAG, Ellex-SuperQ Medical, Australia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigation Into The Impact Of Enteric Coated Of Aspirin In Patients With Newly Diagnosed Ischemic Stroke.
Status: COMPLETED
Conditions: Stroke, Ischemic
Interventions: DRUG: Enteric Coated Aspirin Tablet|DRUG: Plain Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Oxybutynin Chloride Extended-Release Tablets 15 mg and Ditropan XL® Tablets 15 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Oxybutynin Chloride Extended-Release Tablets, 15 mg|DRUG: Ditropan XL® Extended-release tablets, 15 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Use of Nasal High Flow Oxygen During Breaks of Non-invasive Ventilation for Patients With Hypercapnic Respiratory Failure
Status: COMPLETED
Conditions: Hypercapnic Respiratory Failure
Interventions: DEVICE: HFHO Group|DEVICE: Standard O2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sculptra Aesthetic for the Treatment of Upper Knee Skin Laxity
Status: COMPLETED
Conditions: Lax Skin|Knee
Interventions: DEVICE: poly-L-lactic acid to right knee|DEVICE: poly-L-lactic acid to left knee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Outcomes After Laparoscopic Versus Open Appendectomy in Acute Appendicitis
Status: COMPLETED
Conditions: Appendectomy|Pain, Postoperative|Length of Stay
Interventions: PROCEDURE: Appendectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maraviroc as an Immunomodulatory Drug for Antiretroviral-treated HIV Infected Patients Exhibiting Immunologic Failure
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Placebo|DRUG: Maraviroc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HMG Stimulation Versus HRT for Endometrial Preparation Prior to Blastocyst Transfer in Moderate to Severe IUA Patients
Status: COMPLETED
Conditions: Infertility, Female|Intrauterine Adhesion
Interventions: DRUG: human menopausal gonadotrophin|DRUG: hormone replacement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sodium Glucose Co-transporter 2 Inhibitor on Inflammatory Cytokine in Type 2 Diabetes
Status: COMPLETED
Conditions: Type2 Diabetes Mellitus
Interventions: DRUG: Glimepiride|DRUG: Empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Flavanol-rich Cocoa on Peripheral and Cerebral Blood Flow in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes
Interventions: DIETARY_SUPPLEMENT: High Flavanol Cocoa|DIETARY_SUPPLEMENT: Low Flavanol Cocoa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacogenetic Response to Naltrexone For Alcohol Dependence
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ascorbic Acid Treatment in Congenital Glucocorticoids and Mineralocorticoids Deficiency Due to NNT Mutation
Status: UNKNOWN
Conditions: Glucocorticoids Deficiency
Interventions: DRUG: Ascorbic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sentinel Lymph Node Localisation With an Ultra-low Dose of Magtrace in Breast Cancer Patients
Status: RECRUITING
Conditions: Breast Cancer|Sentinel Lymph Node
Interventions: DRUG: Superparamagnetic Iron Oxide|DEVICE: Technetium99
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bortezomib and Thalidomide in Treating Patients With Newly Diagnosed Stage II or Stage III Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: bortezomib|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Evaluation of a Guide to Help People With Parkinson's and Their Caregivers to Self-manage Falling
Status: UNKNOWN
Conditions: Parkinson Disease|Accidental Fall
Interventions: OTHER: Self-management guide for people with Parkinson's who fall and their informal caregivers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of iMRI on the Extent of Resection in Patients With Newly Diagnosed Glioblastomas
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DEVICE: iMRI-guided surgery|DRUG: 5-ALA-guided surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Palifosfamide-tris in Combination With Etoposide and Carboplatin in Patients With Malignancies
Status: UNKNOWN
Conditions: Malignancy|Cancer|Non Small Cell Lung Cancer|Small Cell Lung Cancer|Testicular Cancer|Thymoma|Ovarian Cancer|Osteosarcoma
Interventions: DRUG: palifosfamide-tris
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Low Intensity Training Combined With Partial Restriction of Blood Flow in Individuals With Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Low Intensity Training associated with Partial Blood Flow|OTHER: Low Intensity Training associated with Partial Blood Flow-Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Gather Information on the Kidney Function of Patients With Non-valvular Atrial Fibrillation (Irregularly Heart Beats Which is Not Caused by a Heart Valve Problem) Treated With Rivaroxaban or Vitamin K Antagonists
Status: COMPLETED
Conditions: Non-Valvular Atrial Fibrillation
Interventions: DRUG: Rivaroxaban (Xarelto, BAY-597939)|DRUG: VKAs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Negative Pressure Dressing After Saphenous Vein Harvest
Status: COMPLETED
Conditions: Coronary Artery Disease|Complication of Coronary Artery Bypass Graft|Wound Complication
Interventions: DEVICE: Prevena device (Group A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Muscle Relax Affects Outcomes of Robotic Surgery
Status: UNKNOWN
Conditions: General Anesthesia|Postoperative Complications
Interventions: DRUG: Rocuronium|OTHER: continuous infusion|OTHER: intermittent injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Energy Drink Effects on Performance, Mood, and Cardiovascular Outcomes
Status: COMPLETED
Conditions: Caffeine|Exercise Performance|Energy Drink|Cardiovascular Safety|Mood
Interventions: DIETARY_SUPPLEMENT: Acute energy drink or placebo consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Patient Reminder and Self-Referral Via Online Patient Portals and Text Messaging to Improve Adherence to Breast Cancer Screening
Status: COMPLETED
Conditions: Breast Carcinoma
Interventions: OTHER: Best Practice|BEHAVIORAL: Health Education|OTHER: Interview|OTHER: Planned Notification|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Managing Outpatient Hysteroscopy-associated Pain
Status: COMPLETED
Conditions: Pain|Hysteroscopic Surgery
Interventions: PROCEDURE: ketoprofen for pain relief in office hysteroscopy|PROCEDURE: ketoprofen plus infiltration anesthesia with lidocaine for pain relief in office hysteroscopy|PROCEDURE: ketoprofen plus paracervical block anesthesia with lidocaine for pain relief in office hysteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Inspiratory Muscle Training on Respiratory and Diaphragmatic Functions, Balance Control, Exercise Capacity and Quality of Life in People After Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: OTHER: sham inspiratory muscle training|OTHER: target inspiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Breast Cancer After Ovarian Cancer During and/or After Therapy: Genomic Evaluation
Status: RECRUITING
Conditions: BRCA-Associated Breast Carcinoma
Interventions: GENETIC: Next-generation sequencing (NGS) assay TruSight Oncology 500 (TSO 500).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of Cervical Sympathetic Block for Cerebral Vasospasm Following Aneurysmal Subarachnoid Hemorrhage
Status: TERMINATED
Conditions: Vasospasm
Interventions: DRUG: Cervical Sympathetic Block (bupivicaine, clonidine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incorporating ePrognosis for the Encouragement of Smarter Screening for Breast and Colorectal Cancer in Older Adults
Status: COMPLETED
Conditions: Breast Carcinoma|Colorectal Carcinoma
Interventions: OTHER: Best Practice|OTHER: Informational Intervention|OTHER: Questionnaire Administration|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Comparison of Dexmedetomidine and Midazolam for Prevention of Emergence Delirium in Children
Status: COMPLETED
Conditions: Tonsillitis
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Establishing New Treatment Approaches for Amblyopia: Perceptual Learning and Video Games
Status: RECRUITING
Conditions: Amblyopia
Interventions: BEHAVIORAL: Video Game Vision Training|BEHAVIORAL: Perceptual Learning|BEHAVIORAL: Occlusion Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Suture or Directed Wound Healing? Comparative Study of Their Respective Values Following a Punch Skin Biopsy (CICAT)
Status: UNKNOWN
Conditions: Punch Skin Biopsy
Interventions: PROCEDURE: suture|PROCEDURE: directed wound healing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study on the Reactogenicity, Safety and Immune Response of a Targeted Immunotherapy Against HSV in Healthy Japanese Participants Aged 18-40 Years
Status: COMPLETED
Conditions: Herpes Simplex
Interventions: BIOLOGICAL: HSVTI Formulation 1|BIOLOGICAL: HSVTI Formulation 2|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Non-invasive Vagus Nerve Stimulation for Treatment of Low Weight Eating Disorders
Status: RECRUITING
Conditions: Anorexia Nervosa
Interventions: DEVICE: taVNS|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trabectedin and Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Resistant or Intolerant to a BTK Inhibitor
Status: WITHDRAWN
Conditions: Refractory Chronic Lymphocytic Leukemia|Refractory Small Lymphocytic Lymphoma
Interventions: DRUG: Trabectedin|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Verify the Efficacy of YM177 (Celecoxib) in Postoperative Pain Patients
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: YM177|DRUG: etodolac|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of DHEA and Exercise on Bone Marrow Fat in Postmenopausal Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Low Bone Density|Osteoporosis
Interventions: BEHAVIORAL: Exercise|DIETARY_SUPPLEMENT: DHEA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Whole Prediabetes: A Family-Centered Whole Foods Diet in Adults With Prediabetes and Their Offspring
Status: COMPLETED
Conditions: PreDiabetes
Interventions: BEHAVIORAL: Whole Prediabetes Diet Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ONTAK® in Treating Patients With Advanced Breast Cancer That Did Not Respond to Previous Treatment
Status: COMPLETED
Conditions: Male Breast Cancer|Recurrent Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer
Interventions: BIOLOGICAL: ONTAK|OTHER: flow cytometry|OTHER: immunohistochemistry staining method|OTHER: enzyme-linked immunosorbent assay|OTHER: laboratory biomarker analysis|GENETIC: protein expression analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of an Oral Supplement Enriched in Amino Acids and the Leucine Metabolite B-hydroxy B-methylbutyrate (HMB)
Status: TERMINATED
Conditions: Pressure Ulcers
Interventions: DIETARY_SUPPLEMENT: Nutritional Supplement/Amino acids and HMB|DIETARY_SUPPLEMENT: Juven
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Positive-End Expiratory Pressure in Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Adult
Interventions: OTHER: Positive End-expiratory Pressure (PEEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Model-Based CBRN Training Program
Status: COMPLETED
Conditions: Chemical Accident|Radiation Exposure|Biological Substance Poisoning
Interventions: BEHAVIORAL: Mastery Learning Model for Chemical, Biological, Radiological, and Nuclear threats and hazards (MLM-CBRN Education Program) on student nurses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: EGF-Depleting Therapy CIMAvax-EGF in Combination With Standard Therapy for RAS- and BRAF Wild-Type Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Colo-rectal Cancer
Interventions: BIOLOGICAL: Recombinant Human EGF-rP64K/Montanide ISA 51 Vaccine|DRUG: Leucovorin|DRUG: Oxaliplatin|DRUG: Fluorouracil|BIOLOGICAL: Bevacizumab|DRUG: Irinotecan|BIOLOGICAL: Cetuximab|PROCEDURE: Metastasectomy|PROCEDURE: Biospecimen collection|PROCEDURE: Computed Tomography|BIOLOGICAL: Panitumumbab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tofacitinib for Immune Skin Conditions in Down Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Down Syndrome|Alopecia Areata|Atopic Dermatitis / Eczema|Hidradenitis Suppurativa|Vitiligo|Psoriasis
Interventions: DRUG: Tofacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of TS-172 in Healthy Adult Subjects (Single and Multiple Doses)
Status: COMPLETED
Conditions: Healthy Adult Subjects
Interventions: DRUG: TS-172|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Partnering With Family Members to Prevent, Detect and Manage Delirium in Critically Ill Patients.
Status: ACTIVE_NOT_RECRUITING
Conditions: Delirium|Intensive Care Unit Delirium|Post Intensive Care Unit Syndrome|Post Intensive Care Unit Syndrome Family
Interventions: BEHAVIORAL: Delirium Education, Prevention, and Management|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Strategic Research Program 17 (VUB Funding)
Status: COMPLETED
Conditions: Prosthesis User|Amputation; Traumatic, Limb, Lower
Interventions: DEVICE: AMPfoot 4.0|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Efficacy and Safety of Eribulin Mesylate in Combination With Pembrolizumab in Participants With Metastatic Triple-Negative Breast Cancer (mTNBC)
Status: COMPLETED
Conditions: Breast Neoplasm
Interventions: DRUG: Eribulin Mesylate|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial Seizures
Status: COMPLETED
Conditions: Refractory Partial Seizures
Interventions: DRUG: E2007 (perampanel)|DRUG: E2007 (perampanel)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Immunotherapy Vaccine (PIpepTolDC) for the Treatment of Patients With Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes Mellitus
Interventions: BIOLOGICAL: Tolerogenic Dendritic Cell Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medlink for Diagnosing of Diabetes Mellitus, COPD, CHF, Myasthenia Gravis and Hypertension
Status: COMPLETED
Conditions: Diabetes Mellitus|Chronic Obstructive Pulmonary Disease|Congestive Heart Failure|Myasthenia Gravis|Hypertension
Interventions: DEVICE: Medlink
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study To Investigate The Effect Of PD-217,014 On Abdominal Pain/Discomfort In Patients With IBS.
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: PD-217,014
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Symbiotic & Colonization
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Infant formula|OTHER: Breastfeeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Pembrolizumab Before Surgery for the Treatment of Mismatch Repair Deficient Locally Advanced Solid Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Malignant Solid Neoplasm
Interventions: BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Sympathetic Denervation for the Management of Chronic Hypertension
Status: COMPLETED
Conditions: Uncontrolled Hypertension
Interventions: DEVICE: Biosense Webster Celcius Thermacool catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Alveolar Ridge Preservation Using Different Bone Substitutes
Status: COMPLETED
Conditions: Alveolar Ridge Enlargement
Interventions: DRUG: Toothgraft|DRUG: Allograft|DRUG: Alloplast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits
Status: RECRUITING
Conditions: Epilepsy
Interventions: DRUG: Methylphenidate|OTHER: Placebo|DRUG: Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Controlled Human Rhinovirus Infection Study of 2-Deoxy-D-Glucose in Healthy Adults
Status: RECRUITING
Conditions: Acute Nasopharyngitis
Interventions: DRUG: 2-Deoxy-D-glucose|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Targeted Left Ventricular Lead Placement, Comparison of Active Fixation Bipolar and Passive Quadripolar Pacemaker Leads
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Active fixation bipolar lead versus passive fixation quadripolar leads in Cardiac Resynchronization Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Trial of PX-12 in Patients With a Histologically or Cytologically Confirmed Diagnosis of Advanced or Metastatic Cancer
Status: COMPLETED
Conditions: Metastatic Cancer|Advanced Cancer
Interventions: DRUG: PX-12
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of A-CRA in Compulsory Institutional Care for Youth
Status: RECRUITING
Conditions: Substance Use Disorders|Criminal Behavior
Interventions: BEHAVIORAL: Adolescent Community Reinforcement Approach, A-CRA|BEHAVIORAL: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Fixed Dose, Dose Response Study for Ropinirole Prolonged Release in Patients With Early Stage Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: ropinirole monotherapy|DRUG: placebo monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glucose-induced Glucagon-like Peptide 1 (GLP-1) Secretion in NAFLD Patients Compared to Healthy Controls
Status: COMPLETED
Conditions: Non Alcoholic Fatty Liver Disease|Non Alcoholic Steatohepatitis
Interventions: OTHER: Oral glucose tolerance test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Tolerability Study of Metadoxine Extended Release (MDX) (Previously Known as MG01CI) in PI-ADHD Adolescent Subjects
Status: COMPLETED
Conditions: ADHD, Predominantly Inattentive Type
Interventions: DRUG: Metadoxine extended release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endocannabinoids, Stress, Craving And Pain Effects Study
Status: RECRUITING
Conditions: Opioid Use Disorder
Interventions: DRUG: Palmitoylethanolamide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of 68Ga-DOTA-FAPI-46 and 68Ga-DOTA-2P(FAPI)2 PET/CT in Patients With Various Types of Cancer
Status: COMPLETED
Conditions: Tumor, Solid, FAPI, PET/CT, Metastasis
Interventions: DIAGNOSTIC_TEST: 68Ga-DOTA-FAPI-46 and 68Ga-DOTA-2P(FAPI)2 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Geriatric Ketamine for Pain Management Study
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Morphine|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimization of Radiotherapy in Treatment of Painful Bone Metastasis
Status: COMPLETED
Conditions: Pain|Bone Metastasis
Interventions: RADIATION: Radiotherapy|RADIATION: Radiotherapy|RADIATION: Radiotherapy|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Emotional Freedom Technique on Menopausal Symptoms, Quality of Life and Depression Level
Status: COMPLETED
Conditions: Menopause
Interventions: BEHAVIORAL: Emotional freedom technique group|BEHAVIORAL: Sham emotional freedom technique group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PIEB vs PCEA With Epidural or CSE Technique. A Randomized Double Blind Clinical Trial
Status: COMPLETED
Conditions: Labor Epidural Analgesia
Interventions: DEVICE: PCEA vs PIEB|PROCEDURE: Epidural vs CSE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: GALLANT 9 Tesaglitazar vs. Placebo in Combination With Insulin
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Tesaglitazar 0.5|DRUG: Insulin at least 30 units/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Fetoscopic Endoluminal Tracheal Occlusion for Severe Left and Right Congenital Diaphragmatic Hernia
Status: NOT_YET_RECRUITING
Conditions: Congenital Diaphragmatic Hernia
Interventions: DEVICE: BALT GOLDBAL2 Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the Free Margin Cusp Sizer (CALIBRATE)
Status: RECRUITING
Conditions: Aortic Valve Regurgitation|Aortic Root Aneurysm
Interventions: DEVICE: Free Margin Cusp Sizer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Exercise and Targeted Therapy for Post-Stroke Reading Deficits
Status: RECRUITING
Conditions: Stroke|Aphasia|Reading Disorder
Interventions: BEHAVIORAL: Phono-Motor Therapy|BEHAVIORAL: Aerobic Exercise Training (AET)|BEHAVIORAL: Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hip DAA Closure Techniques
Status: ENROLLING_BY_INVITATION
Conditions: Total Hip Replacement|Wound Complication
Interventions: PROCEDURE: wound closure subcuticular running stitch using 3-0 monocryl suture without skin adhesive|PROCEDURE: wound closure subcuticular running stitch using 3-0 monocryl suture with two layers of skin adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adherence to Antimalarial Drugs in Sierra Leone
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: amodiaquine-artesunate (AQAS) fixed-dose|DRUG: Artemether-lumefantrine combination (AL) dispersable
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Restylane Contour in the Treatment of Temple Hollowing
Status: ACTIVE_NOT_RECRUITING
Conditions: Temporal Hollowing
Interventions: DEVICE: Restylane Contour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multidisciplinary Research Into the Effects of Resistance Exercise and Whey Protein Supplementation in Healthy Older Men
Status: COMPLETED
Conditions: Sarcopenia|Muscle Atrophy
Interventions: DIETARY_SUPPLEMENT: Whey Protein|DIETARY_SUPPLEMENT: Control|OTHER: Resistance Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: FDG PET Imaging in Diagnosing Patients With Glioblastoma
Status: COMPLETED
Conditions: Brain Glioblastoma
Interventions: PROCEDURE: Computed Tomography|RADIATION: Fludeoxyglucose F-18|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Clinical and Psychological Impact of Vitamin D Replacement in Adolescent Females at Risk for Polycystic Ovarian Syndrome (PCOS)
Status: NOT_YET_RECRUITING
Conditions: Polycystic Ovarian Syndrome in Adolescent Females|Vitamin D Deficiency
Interventions: DRUG: Vitamin D 4000IU daily|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AR Enhanced Pictorial Warnings on Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Brief AWARD advice and active referral to somking cessation services|BEHAVIORAL: Chat-based support through Instant Messaging apps|OTHER: Leaflet|BEHAVIORAL: AR images
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Study of MP-214 in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: MP-214 3mg|DRUG: MP-214 6mg|DRUG: MP-214 9mg|DRUG: Risperidone 4mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Schizophrenia Imaging
Status: UNKNOWN
Conditions: Foetal Differences Between Healthy and Schizophernic Parents
Interventions: DEVICE: imaging follow up: MRI scan|DEVICE: imaging follow up: Ultrasonographic examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Blood Flow Restriction Exercise in Patients With an Achilles Tendon Rupture
Status: NOT_YET_RECRUITING
Conditions: Achilles Tendon Rupture
Interventions: OTHER: Exercise with partial Blood Flow Restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Phase 2 Extension Study of Higher Dose Sialic Acid-Extended Release (SA-ER) Tablets and Sialic Acid-Immediate Release (SA-IR) Capsules in Patients With Glucosamine (UDP-N-acetyl)-2-Epimerase (GNE) Myopathy
Status: COMPLETED
Conditions: GNE Myopathy|Hereditary Inclusion Body Myopathy (HIBM)
Interventions: DRUG: SA-ER 500 mg|DRUG: SA-IR 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics and Hemodynamic Changes in Cirrhosis
Status: COMPLETED
Conditions: Cirrhosis
Interventions: DRUG: Saccharomyces Boulardii Probiotic Supplement|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of N-acetylcysteine on Cardiorespiratory Control in COPD Patients With Mild-to-moderate Airflow Obstruction
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: N-acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study to Assess the Biological Activity of ZD6126 in Subjects With Newly Diagnosed Metastatic Renal Cell Carcinoma (Stage IV)
Status: SUSPENDED
Conditions: Carcinoma, Renal Cell|Kidney Neoplasms
Interventions: DRUG: ZD6126|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study to Compare the Pharmacokinetics of Two Formulations of Siklos® in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Hydroxycarbamide dispersible tablets|DRUG: Hydroxycarbamide film-coated tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate Efficacy and Safety of HCP1803 Compared to RLD2001-1 in Patients With Essential Hypertension
Status: RECRUITING
Conditions: Hypertension
Interventions: DRUG: HCP1803-3|DRUG: RLD2001-1|DRUG: HPP2003-3|DRUG: HPP2002-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Liposomal Doxorubicin in Treating Patients With Persistent or Recurrent Cancer of the Cervix
Status: TERMINATED
Conditions: Cervical Cancer
Interventions: DRUG: pegylated liposomal doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effectiveness of TNI vs. BiPAP in Chronic Global Insufficiency in COPD Patients
Status: COMPLETED
Conditions: COPD Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: nHF|DEVICE: BiPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study Between Infraclavicular and Axillary Blocks for Assessment of Motor Power Using Handgrip Dynamometer
Status: COMPLETED
Conditions: Hand Surgery|Ultrasound Guided
Interventions: PROCEDURE: axillary block|PROCEDURE: infraclavicular block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Dasiglucagon for Treatment of Post-bariatric Hypoglycemia in Roux-en-Y Gastric Bypass (RYGB) Operated Adults
Status: WITHDRAWN
Conditions: Hypoglycemia|Glucose Metabolism Disorders
Interventions: DRUG: Dasiglucagon|DRUG: Dasiglucagon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human Granulocyte Macrophage Colony Stimulating Factor(rhGM-CSF) Treating Oral Mucositis
Status: UNKNOWN
Conditions: Nasopharyngeal Cancers
Interventions: DRUG: rhGM-CSF|DRUG: Compound Vitamin B12
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of CNP-106 in Subjects With Myasthenia Gravis
Status: RECRUITING
Conditions: Myasthenia Gravis|Generalized Myasthenia|AChR Myasthenia Gravis|MuSK MG
Interventions: DRUG: CNP-106|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity Behavioral Intervention in Obese Endometrial Cancer Survivors
Status: COMPLETED
Conditions: Stage IA Uterine Corpus Cancer|Stage IB Uterine Corpus Cancer|Stage II Uterine Corpus Cancer|Stage IIIA Uterine Corpus Cancer|Stage IIIB Uterine Corpus Cancer|Stage IIIC Uterine Corpus Cancer|Stage IVA Uterine Corpus Cancer|Stage IVB Uterine Corpus Cancer
Interventions: BEHAVIORAL: Exercise Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Irinotecan and Docetaxel in Patients With Metastatic or Unresectable Gastric or Gastroesophageal Junction Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Cancer|Esophageal Neoplasms
Interventions: DRUG: irinotecan, docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Psychological Intervention for Parents of Adolescents
Status: UNKNOWN
Conditions: Parent-Child Relations
Interventions: BEHAVIORAL: The Open Door Approach to Parenting Teenagers (APT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determine Toxicity and Antibody Responses With a KLH Conjugated Bivalent Vaccine Containing GD2 Lactone, GD3 Lactone With Immunological Adjuvant QS-DG or OPT-821 in Patients With Disease Free AJCC Stage III or IV Cutaneous Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: KLH conjugates with GD2L and GD3L
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Drinking Water and Normal Saline in Irrigating Traumatic Wound
Status: NOT_YET_RECRUITING
Conditions: Trauma
Interventions: PROCEDURE: Irrigating Traumatic Wound with Drinking Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparing Astragalus Plus Gemcitabine to Gemcitabine Alone as Neoadjuvant Treatment for Pancreatic Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: Astragalus + Gemcitabine|DRUG: Gemcitabine alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT