pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Dual-focus Magnification With Narrow-band Imaging in Helicobacter Pylori Infection
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DEVICE: Dual focus with narrow band imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Bepreve vs. Alrex in Subjects With Moderate to Severe Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: bepotastine besilate, 1.5%|DRUG: Loteprednol etabonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Evaluating the Efficacy and Safety of Daratumumab in Subjects With Relapsed/Refractory B-cell or T-cell Precursor Acute Lymphoblastic Leukemia (ALL)
Status: WITHDRAWN
Conditions: Malignant Neoplasms Stated as Primary Lymphoid Haematopoietic
Interventions: DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of IPOVAC in Young Children
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: IMOVAC-POLIO|BIOLOGICAL: IPOVAC 1.5:5:5|BIOLOGICAL: IPOVAC, 3:10:10|BIOLOGICAL: IPOVAC, 6:20:20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of a Single TRUS-guided Intraprostatic Injection of NX-1207 in Patients With LUTS Due to BPH
Status: TERMINATED
Conditions: Lower Urinary Tract Symptoms
Interventions: DRUG: NX-1207|DRUG: Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Hetrombopag in Healthy and Hepatic Impairment Subjects
Status: COMPLETED
Conditions: Sever Aplastic Anaemia
Interventions: DRUG: Hetrombopag Olamine Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visual Performance, Patient Satisfaction and PCO Rate After Implantation of a Trifocal Hydrophobic IOL
Status: COMPLETED
Conditions: Cataract|Lens Opacities|Presbyopia
Interventions: DEVICE: IOL implantation experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib With Rituximab and Lenalidomide in Relapsed/Refractory B-cell Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Non-hodgkin Lymphoma,B Cell
Interventions: DRUG: Acalabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Omega-3 Inhibit Metabolic Syndrome
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Hypertension|Hyperlipidemia|Obesity
Interventions: OTHER: low glycemic diet|DIETARY_SUPPLEMENT: vitamin D omega-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early vs Delayed Weightbearing After Surgical Fixation of Unstable Ankle Fractures With Syndesmosis Disruption
Status: RECRUITING
Conditions: Unstable Ankle Fractures With Syndesmotic Disruption
Interventions: PROCEDURE: Early Weightbearing management post operation|PROCEDURE: Delayed Weightbearing management post operation (Traditional)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Stigma Among Individuals With Addiction and Staff in the Criminal Justice System
Status: COMPLETED
Conditions: Stigma, Social|Behavior
Interventions: BEHAVIORAL: Stigma Awareness Training for Legal System Staff|BEHAVIORAL: Acceptance and Commitment Therapy for self-stigma
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Subjects to Assess the Pharmacokinetics of Savolitinib When Administered Alone and in Combination With Rifampicin
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Savolitinib|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tolerability and Safety of Duloxetine BID in Healthy Female Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Duloxetine - low dose|DRUG: Duloxetine - high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of Carboplatin/Paclitaxel With Pegfilgrastim Supported by Haematopoietic Progenitor Cell Re-Infusion in Whole Blood
Status: COMPLETED
Conditions: Breast Cancer|Lung Cancer|Ovarian Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|DRUG: pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Technology-Based Intervention for Reducing Sexually Transmitted Infections and Substance Use During Pregnancy
Status: ACTIVE_NOT_RECRUITING
Conditions: Sexually Transmitted Infection|Alcohol Use Complicating the Puerperium|Alcohol Use Complicating Pregnancy, Unspecified Trimester|Drug Use
Interventions: BEHAVIORAL: Health Check-up for Expectant Moms|BEHAVIORAL: Time, attention, and information-matched control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Costal Mobilization Techniques and Manual Diaphragm Release Technique in Patients COPD
Status: UNKNOWN
Conditions: Copd|Chest Disorders|Diaphragmatic Disorder
Interventions: OTHER: GROUP Costal mobilization & Diaphragm Release|OTHER: GROUP Manual Diaphragm Release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: BR1010 in Patients With Essential Hypertension Patients Who do Not Adequately Respond to Fimasartan/Amlodipine Combination
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Fimasartan/Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Pre-Diabetes Interventions and Continued Tracking to Ease-out Diabetes (Pre-DICTED) Program
Status: COMPLETED
Conditions: Pre-diabetes
Interventions: BEHAVIORAL: Lifestyle modification|DRUG: Metformin|OTHER: Financial incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Imovax® Rabies and VERORAB® Immunogenicity and Safety After One Week 2-sites Intradermal or 1-site Intramuscular Pre-Exposure Prophylaxis Regimens, Followed by a Simulated Post-Exposure Prophylaxis Regimen at One Year
Status: COMPLETED
Conditions: Healthy Volunteers (Rabies Immunization)
Interventions: BIOLOGICAL: HDCV|BIOLOGICAL: HDCV|BIOLOGICAL: PVRV|BIOLOGICAL: PVRV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ablation as First Line Treatment in Paroxysmal Atrial Fibrillation
Status: UNKNOWN
Conditions: Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: Catheter ablation using cryothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain Protocol Limiting Narcotics for Laparoscopic Hand-assisted Donor Nephrectomy
Status: TERMINATED
Conditions: Narcotic Use|Renal Transplant Donor of Left Kidney
Interventions: DRUG: Ketamine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of PRAX-114 in Participants With Essential Tremor
Status: WITHDRAWN
Conditions: Essential Tremor
Interventions: DRUG: 10 mg PRAX-114, 20 mg PRAX-114, and Placebo|DRUG: 10 mg PRAX-114 or 20 mg PRAX-114
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: XIENCE 28 Global Study
Status: COMPLETED
Conditions: Bleeding Disorder|Stroke, Ischemic|Stroke Hemorrhagic|Hematological Disease|Thrombocytopenia|Coagulation Disorder|Anemia|Renal Insufficiency|Coronary Artery Disease
Interventions: DEVICE: XIENCE|DRUG: DAPT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flexible Ureteroscopy Versus ESWL in the Management of Lower Calyceal Stones
Status: COMPLETED
Conditions: Renal Stones
Interventions: PROCEDURE: Ureteroscopy|PROCEDURE: Shockwave lithotripsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation Laser Therapy Following Arthroscopic Rotator Cuff Repair
Status: COMPLETED
Conditions: Rotator Cuff Tears
Interventions: DEVICE: B-Cure Pro|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Detection of Lung Tumors by Sniffer Dogs - Evaluation of Sensitivity and Specificity
Status: COMPLETED
Conditions: Lung Cancer|Chronic Obstructive Airway Disease
Interventions: PROCEDURE: exhalation analysis of breath sample|PROCEDURE: exhalation analysis of breath sample|PROCEDURE: exhalation analysis of breath sample
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Influence of Dietary Fiber-rich Meals on Gene Expression and Postprandial Glucose and Lipid Response
Status: COMPLETED
Conditions: Hypoglycemia|Hyperglycemia
Interventions: OTHER: Oat bran|OTHER: Spray-dried oat drink|OTHER: Rye bran|OTHER: Sugar beet fiber|OTHER: Mixture of fiber|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Safety, Tolerability and PK of Repeat Administration of Intravenous ETI-204 in Adult Volunteers
Status: COMPLETED
Conditions: Inhalational Anthrax
Interventions: BIOLOGICAL: ETI-204|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study to Find the MTD of SYN125 in People With Solid Tumors and the MTD of SYN125 With a Fixed Dose of SYN004 in People in Patients With Epithelial Cancers With EGFR Expressions
Status: ACTIVE_NOT_RECRUITING
Conditions: Epithelial Carcinoma|Solid Tumor
Interventions: BIOLOGICAL: SYN125|BIOLOGICAL: SYN004
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endovascular Thrombectomy Alone Versus Intravenous Thrombolysis Plus Thrombectomy on Acute Basilar Artery Occlusion
Status: RECRUITING
Conditions: Basilar Artery Occlusion|Acute Cerebrovascular Accident|Stroke Due to Basilar Artery Occlusion
Interventions: DRUG: Intravenous thrombolysis|PROCEDURE: Endovascular thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Mineral Density Study In Patients With Chronic Obstructive Pulmonary Disease. DISKUS® Inhaler is a Trademark of the GSK Group of Companies.
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Salmeterol 50 mcg BID|DRUG: Fluticasone Propionate/Salmeterol 250/50 mcg BID|DEVICE: DISKUS inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Efficacy of Levocetirizine to Placebo in Reducing Symptoms of Seasonal Allergic Rhinitis (SAR) in Sensitive Subjects Exposed to Ragweed Pollen
Status: COMPLETED
Conditions: Rhinitis|Allergic|Seasonal
Interventions: DRUG: Placebo drops|DRUG: Placebo tablets matching to levocetirizine|DRUG: Placebo tablets matching to cetirizine|DRUG: Levocetirizine drops|DRUG: Levocetirizine tablets|DRUG: Cetirizine drops|DRUG: Cetirizine tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Mid-term Results of Total Correction of TOF Between Preservation of PV and Trans-annular Patch.
Status: UNKNOWN
Conditions: Tetrology of Fallot
Interventions: PROCEDURE: TOF repair with trans-annular patch VS preservation of PV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I Study of the Pharmacokinetic Variability and Relative Bioavailability of the Phase 3 and Common Blend Formulations of Eliglustat in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Eliglustat, common blend proposed commercial formulation|DRUG: Eliglustat, Phase 3 capsule formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Training Delivered Remotely to Individuals With Psychosis (ROAM)
Status: COMPLETED
Conditions: Treatment|Active Control|Schizophrenia|Psychosis|Schizoaffective Disorder|Psychotic Depression|Psychotic Mood Disorders|Psychotic Disorders|Psychotic Episode|Cognitive Impairment
Interventions: BEHAVIORAL: Structured Cognitive Training & PRIME|BEHAVIORAL: Computer Games Control & PRIME
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety,Preliminary Pharmacodynamics and Pharmacokinetics Study of rExenatide-4 in Chinese Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: BIOLOGICAL: rExenatide-4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diuretic Efficacy of Aminophylline and Furosemide Combination vs Furosemide Alone in Critically Ill Adults
Status: RECRUITING
Conditions: Acute Kidney Injury
Interventions: DRUG: Aminophylline|DRUG: Frusemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Efficacy of Various Pain Alleviating Methods in Reducing Pain in Children During Intraoral Local Anaesthetic Injections
Status: UNKNOWN
Conditions: Anesthesia, Local
Interventions: DRUG: 20% benzocaine gel|DEVICE: Transcutaneous electric nerve stimuli|DRUG: Emla gel|OTHER: Ice application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Phase I Concentration-Controlled Trial to Assess the Safety, Tolerance, Pharmacokinetics and Development of Decreased HIV-1 Susceptibility to the Combination of Atevirdine Mesylate (U-87201E), Zidovudine (AZT), and Didanosine (ddI)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Atevirdine mesylate|DRUG: Zidovudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Treatment Outcomes After Receiving Conventional Clasp or Precision Attachment Removable Partial Dentures.
Status: UNKNOWN
Conditions: Bilateral Edentulous Mandible (Kennedy Class I)
Interventions: DEVICE: OT Cap attachment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Paclitaxel and Carboplatin in Combination With Bexarotene Oral Capsules in Patients With Advanced Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-small-cell Lung
Interventions: DRUG: Bexarotene (targretin)|DRUG: Bexarotene (targretin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Safety, Tolerability and Pharmacokinetics of a Single Ascending Dose of AZD1704
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: AZD1704
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: AI Prediction of Post-Induction Hypotension in Cesarean Sections With Spinal Anesthesia
Status: RECRUITING
Conditions: Spinal Anesthesia Induced Hypotension|Caeserian Section
Interventions: PROCEDURE: Spinal Anesthesia|DIAGNOSTIC_TEST: Blood Sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metabolic Response to Variations in Dietary Glycemic Index
Status: RECRUITING
Conditions: Healthy|Hunger|Food Preferences
Interventions: BEHAVIORAL: High glycemic index|BEHAVIORAL: Medium glycemic index|BEHAVIORAL: Low glycemic index
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lenalidomide Combined With Modified DA-EPOCH and Rituximab (EPOCH-R2) in Primary Effusion Lymphoma or KSHV-associated Large Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Effusion Lymphoma|B-Cell Neoplasm
Interventions: DRUG: Lenalidomide|DRUG: Rituximab|DRUG: Prednisone|DRUG: Etopside|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postpartum Depression in the Covid-19 Pandemic and the Impact of Anaesthesia
Status: COMPLETED
Conditions: Postpartum Depression|Psychological Stress|Maternal Distress
Interventions: OTHER: PHQ-9 (Patient Health Questionnaire) Depression Scale|OTHER: GAD-7 (General Anxiety Disorder) scale|OTHER: 38 questions questionnaire|OTHER: EPDS (Edinburgh Postnatal Depression Scale)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Home Telemonitoring System for Wearable Fetal-ECG and EHG Acquisition During Pregnancy
Status: COMPLETED
Conditions: Uterine Contractions; Prolonged|Fetal Heart Rate or Rhythm Abnormality Affecting Fetus|Pregnancy Related|Home Range
Interventions: DEVICE: use wearable devices to monitoring fetal health conditions.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Total Dose and Efficacy of Two Lidocaine Concentrations Needed for Cutaneous Surgery Local Anesthesia
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase 2a Clinical Trial to Evaluate the Efficacy and Safety of HL301 on Radiation Pneumonitis in Non-small Cell Lung Cancer Patients
Status: UNKNOWN
Conditions: Radiation Pneumonitis|Lung Cancer
Interventions: DRUG: HL301 tablet 300mg|DRUG: Placebo of HL301 tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Preliminary Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low-weight Infants
Status: TERMINATED
Conditions: Patent Ductus Arteriosus
Interventions: DEVICE: Cather closure of patent ductus arteriosus (PDA)|OTHER: Conservative management of patent ductus arteriosus (PDA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Significance of FDG PET/CT Dynamic Imaging in Detecting Metastatic Lymph Nodes With Papillary Thyroid Cancer.
Status: RECRUITING
Conditions: Positron-Emission Tomography|Lymph Node Metastases|Thyroid Cancer
Interventions: DIAGNOSTIC_TEST: <Sup>18<Sup>F-FDG PET/CT dynamic scan|DIAGNOSTIC_TEST: B-ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 1/2, Open-label, Dose Finding Study to Evaluate CC-122 in Combination With Ibrutinib and Obinutuzumab in Subjects With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Status: COMPLETED
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell
Interventions: DRUG: CC-122|DRUG: Ibrutinib|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Potassium Sodium Hydrogen Citrate Therapy on Renal Stone Recurrence and/or Residual Fragments After Shockwave Lithotripsy and Percutaneous Nephrolithotomy in Calcium Oxalate Urolithiasis
Status: COMPLETED
Conditions: Kidney Calculi
Interventions: DRUG: Potassium-sodium citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Tyrosine Kinase Lyn and Cleaved Form by Caspases in Psoriasis
Status: COMPLETED
Conditions: Psoriasis|Atopic Dermatitis
Interventions: OTHER: 3 Biopsies|OTHER: 2 biopsies|OTHER: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: ThrombElastoGraphic Haemostatic Status and Antiplatelet Therapy After Coronary Artery Bypass Graft Surgery
Status: UNKNOWN
Conditions: Graft Patency|Coronary Artery Bypass Grafting Surgery|Hypercoagulability|Thrombosis
Interventions: DRUG: Clopidogrel+acetylsalicylic acid|DRUG: acetylsalicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Low-dose Ticagrelor
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Ticagrelor|DRUG: ticagrelor|DRUG: ticagrelor|DRUG: clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Everolimus With Investigator's Choice of Chemotherapy in Advanced Triple-Negative Breast Cancer (TNBC) With Luminal Androgen Receptor (LAR) Subtype
Status: RECRUITING
Conditions: Triple Negative Breast Cancer|Metastatic Breast Cancer|Mutation
Interventions: DRUG: Everolimus|DRUG: Investigator's Choice of Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefits of a Psychoeducation Program for Those Awaiting Treatment for OCD and OCD Spectrum Disorders
Status: WITHDRAWN
Conditions: Obsessive-Compulsive Disorder|Anxiety Disorders
Interventions: BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Nurse-led Education on Parent's Anxiety and Depression on Managing Side Effects of Chemotherapy
Status: COMPLETED
Conditions: Chemotherapy Effect
Interventions: OTHER: Multimedia education, booklet Providence and tele-nursing follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effects of Stretching Types on Gastrocnemius
Status: COMPLETED
Conditions: Stretch
Interventions: OTHER: Static Stretching|OTHER: Dynamic Stretching|OTHER: PNF Stretching|OTHER: Sham stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Assess Dry Mouth Relief After Using an Experimental Mouth Rinse
Status: COMPLETED
Conditions: Dry Mouth
Interventions: DEVICE: Marketed Dry Mouth Rinse|OTHER: Water control|DEVICE: Experimental Dry Mouth Rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validity of Radical 7 Masimo Monitor at Measuring Hemoglobin in Pediatric Cardiac Intensive Care
Status: UNKNOWN
Conditions: Evaluate the Accuracy of the Masimo Radical 7 Hemoglobin Noninvasive Monitor
Interventions: DIAGNOSTIC_TEST: Radical 7 Masimo Hemoglobin pulse co-oximeter non invasive monitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lumbar Drainage of Intraventricular Hemorrhage
Status: NOT_YET_RECRUITING
Conditions: Intraventricular Hemorrhage|Lumbar Drainage|External Ventricular Drainage
Interventions: OTHER: External drainage of intraventricular hemorrhage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Zinc Supplementation in Low Birth Weight Infants on Severe Morbidity, Mortality and Zinc Status: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Diarrhea|Respiratory Infection|Low Birth Weight
Interventions: DRUG: Zinc|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Sonu Nasal Congestion Relief Study in Patients Suffering From Moderate to Severe Nasal Congestion
Status: COMPLETED
Conditions: Nasal Congestion and Inflammations
Interventions: DEVICE: Sonu
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Trauma- Formula-Driven Versus Lab-Guided Study (TRFL Study)
Status: COMPLETED
Conditions: Hemorrhagic Shock|Trauma Coagulopathy
Interventions: OTHER: Massive transfusion protocol|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitrectomy and Bevacizumab for Diffuse Diabetic Macular Edema
Status: TERMINATED
Conditions: Diffuse Diabetic Macular Edema
Interventions: PROCEDURE: Bevacizumab + Pars plana vitrectomy|PROCEDURE: Bevacizumab + pars plana vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carpal Tunnel Syndrome in Patients With Psoriatic Arthritis; Ultrasonography and Magnetic Resonance Imaging Findings
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|Psoriatic Arthritis
Interventions: DIAGNOSTIC_TEST: Ultrasonography, Magnetic resonance imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Effects of ART and STM in Shoulder Impingement Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Shoulder Impingement Syndrome
Interventions: OTHER: Active Release Technique|OTHER: Soft Tissue Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pharmacokinetic Study of Anlotinib Hydrochloride Capsules in Healthy Subjects and Liver Dysfunction Patients
Status: UNKNOWN
Conditions: Liver Dysfunction
Interventions: DRUG: Anlotinib Hydrochloride Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Non-ablation in the Treatment of Women With Urinary Stress Incontinence: Study Pilot
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DEVICE: Tonederm® (Radiofrequency non ablative)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Outcome Evaluation of Ceramic Crowns Using Two Different Dental Cements
Status: COMPLETED
Conditions: Sensitivity to Dental Cements|Dental Crowns|Dental Three-unit Bridges
Interventions: DEVICE: Full ceramic crowns or 3-unit fixed partial dentures.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rectal Misoprostol Versus Sublingual Misoprostol Prior to Myomectomy
Status: COMPLETED
Conditions: Bleeding During Myomectomy
Interventions: DRUG: rectal misoprostol|DRUG: sublingual misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intravenous Acetaminophen Use With Bariatric Surgery on Morbidly Obese Patients
Status: TERMINATED
Conditions: Obesity|Pain
Interventions: DRUG: Acetaminophen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Research Study to Evaluate the Effects of Repeated Intravitreal Injections on Bacteria Around the Eye
Status: UNKNOWN
Conditions: Central Retinal Vein Occlusion|Choroidal Neovascularization|Age-related Macular Degeneration|Branch Retinal Vein Occlusion
Interventions: PROCEDURE: Conj flora Antibiotic resistance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Translating the DPP Into the Community
Status: COMPLETED
Conditions: Prediabetic State|Overweight|Obesity
Interventions: BEHAVIORAL: Brief counseling plus group diabetes prevention in community|BEHAVIORAL: Brief Counseling for pre-diabetes alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Restylane Perlane Compared to Restylane for Correction of Moderate and Severe Nasolabial Folds
Status: COMPLETED
Conditions: Nasolabial Folds in Chinese Population
Interventions: DEVICE: Restylane Perlane|DEVICE: Restylane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of PXL01 Versus Placebo to Inhibit Adhesion Formation After Flexor Tendon Surgery
Status: COMPLETED
Conditions: Surgical Adhesions
Interventions: DRUG: PXL01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hygiene Protocol of Complete Dentures
Status: COMPLETED
Conditions: Denture Hygiene Protocol
Interventions: OTHER: water|OTHER: sodium hypochlorite|OTHER: sodium bicarbonate|OTHER: chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Optimal Dose of GnRH Agonist for Triggering Final Oocyte Maturation in High Risk OHSS Patients
Status: UNKNOWN
Conditions: Subfertility
Interventions: DRUG: 0.1 mg triptorelin|DRUG: 0.2 mg triptorelin|DRUG: 0.4 mg triptorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stratified Treatment to Ameliorate Diastolic Left Ventricular Stiffness in Heart Failure With Preserved Ejection Fraction
Status: UNKNOWN
Conditions: Heart Failure, Diastolic
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Inspiratory Muscle Training During PR on Dyspnoea and Exercise Tolerance in COPD Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Pulmonary rehabilitation+IMT|OTHER: Pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SCORE Emerging Adult Cannabis Use & Stress
Status: RECRUITING
Conditions: Cannabis Use Disorder
Interventions: DRUG: Cannabidiol oral solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Asthma Mobile Intervention to Promote Patient-Reported Outcomes in Primary Care
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: ASTHMAXcel mobile application|OTHER: Outpatient primary care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Acute and Chronic Nicotine Modulation of Reinforcement Learning
Status: COMPLETED
Conditions: Nicotine Addiction
Interventions: DRUG: Nicotine polacrilex|DRUG: Placebo|OTHER: satiety|OTHER: abstinence
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: CEReBral AutorEgulation in Non-cardiac SuRgery and Relationship to Postoperative DeliriUm State
Status: NOT_YET_RECRUITING
Conditions: Perioperative/Postoperative Complications|Postoperative Cognitive Dysfunction|Postoperative Delirium|EEG With Periodic Abnormalities|Intraoperative Hypotension|Cerebral Hypoperfusion
Interventions: DIAGNOSTIC_TEST: Intra-op EEG and CO data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Immunogenicity of MVA.HIVconsv in HIV-1 Seropositive Adults on HAART
Status: TERMINATED
Conditions: HIV-1
Interventions: BIOLOGICAL: MVA.HIVconsv low dose|OTHER: Placebo low dose|BIOLOGICAL: MVA.HIVconsv high dose|OTHER: Placebo high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Treatment With a Nutraceutical Combination on Sub-optimal LDL Cholesterol Levels
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Nutraceutical combination|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Integrated CBT-I and PE on Sleep and PTSD Outcomes (Impact Study)
Status: COMPLETED
Conditions: Posttraumatic Stress Disorders|Chronic Insomnia
Interventions: BEHAVIORAL: CBTI-PE|BEHAVIORAL: Hygiene-PE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotic Supplementation in the Dysbiosis of Bowel Preparation
Status: UNKNOWN
Conditions: Microbial Colonization|Irritable Bowel Syndrome|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Infloran probiotic|DIETARY_SUPPLEMENT: HAC probiotic|DIETARY_SUPPLEMENT: Infloran placebo|DIETARY_SUPPLEMENT: HAC placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optical Polyp Testing for In Vivo Classification
Status: COMPLETED
Conditions: Colonic Polyp|Colonic Diseases|Colonic Neoplasms|Colonic Adenoma|Colonic Adenocarcinoma|Colonic Dysplasia|Colonic Carcinoma|Colonic Cancer|Colon Hyperplastic Polyp
Interventions: DEVICE: Optical spectral reflectance and autofluorescence imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Nerve Stimulator for Patients With Upper Extremity Disease, Vascular or Orthopedic Surgery
Status: TERMINATED
Conditions: Other Biomechanical Lesions of Upper Extremity
Interventions: PROCEDURE: Local anesthetic block [0.35% marcaine]|DEVICE: Braun DIG-R-C Stimuplex Blockade Monitor System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recreational Basketball to Increase Participation in Diabetes Prevention
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes|PreDiabetes
Interventions: BEHAVIORAL: NDPP + Basketball (BB)|BEHAVIORAL: NDPP Standard of Care SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Combination Therapy vs Single Agent Therapy for Treatment of Urge Incontinence.
Status: TERMINATED
Conditions: Urinary Urge Incontinence
Interventions: DRUG: Oxybutynin extended release|DEVICE: Posterior Tibial Nerve Stimulation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 2-year Longitudinal Study on the Structural and Optical Effects of Orthokeratology Treatment on Eye
Status: COMPLETED
Conditions: Myopic Progression
Interventions: DEVICE: Orthokeratology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Silica and Asbestos Fibres on the Efferocytosis Capacities of Macrophages
Status: COMPLETED
Conditions: History of Exposure to Silica or Asbestosis|Positive Testing for ANA as a Marker of Systemic Autoimmune Diseases
Interventions: BIOLOGICAL: Blood collection|BIOLOGICAL: Blood sample|BIOLOGICAL: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Photodynamic Therapy on Plaque in Orthodontic Patients
Status: NOT_YET_RECRUITING
Conditions: Plaque, Dental|Dental Plaque Induced Gingivitis|White Spot Lesion
Interventions: OTHER: Photodynamic therapy|OTHER: Tricalcium phosphate (TCP) varnish with 5% NaF|OTHER: Chlorhexidine varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: OCT-angiography as a Pronostic Marker for Visual Impairment in Patients Undergoing Neurosurgery for Compressive Macroadenoma : a Prospective Study.
Status: COMPLETED
Conditions: Pituitary Adenoma
Interventions: PROCEDURE: Neurosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: LEAD IT! An App to Enable Persons With Early Stage Dementia to Lead Group Activities for Their Peers
Status: COMPLETED
Conditions: Dementia, Vascular|Alzheimer Disease|Dementia, Mixed
Interventions: BEHAVIORAL: LEAD IT! Programming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ethaselen for the Treatment of Thioredoxin Reductase High Expression Advanced Non-small Cell Lung Cancers
Status: COMPLETED
Conditions: Carcinoma, Non-small Cell Lung
Interventions: DRUG: ethaselen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PCSK9 Inhibition After Heart Transplantation
Status: ENROLLING_BY_INVITATION
Conditions: Vasculopathy
Interventions: BIOLOGICAL: alirocumab|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-sedation Versus Sedation With a Daily Wake-up Trial in Critically Ill Patients Receiving Mechanical Ventilation - Effects on Physical Function
Status: COMPLETED
Conditions: Critically Ill|Muscular Atrophy
Interventions: OTHER: Non-sedation|OTHER: Sedation, control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies
Status: RECRUITING
Conditions: B-cell Lymphoma|Non-Hodgkin Lymphoma|B-cell Malignancy|Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)|Follicular Lymphoma|Mantle Cell Lymphoma|Marginal Zone Lymphoma|Large B-cell Lymphoma
Interventions: BIOLOGICAL: CTX112
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-FLT (PET/CT) in Prefibrotic/Early Primary Myelofibrosis and Essential Thrombocythemia
Status: UNKNOWN
Conditions: Essential Thrombocythemia|Primary Myelofibrosis, Fibrotic Stage|Primary Myelofibrosis, Prefibrotic Stage
Interventions: DEVICE: Diagnostic (18F-FLT PET/CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility and Impact of a Tele-rehabilitation Program in Patients With Chronic and Non-specific Neck Pain
Status: COMPLETED
Conditions: Chronic Non-specific Neck Pain
Interventions: OTHER: MANUAL THERAPY|OTHER: THERAPEUTIC EXERCISE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Amorphous Calcium Carbonate (Acc) Versus Crystalline Calcium Carbonate (Ccc) Using Stable Calcium Isotopes In Postmenopausal Women
Status: UNKNOWN
Conditions: Postmenopause
Interventions: OTHER: CCC|OTHER: ACC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing the Safety of Switching From Lamivudine to Adefovir Dipivoxil Versus Overlapping Lamivudine and Adefovir Before Adefovir Dipivoxil Monotherapy in Patients With Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Adefovir Dipivoxil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2140023 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: LY2140023|DRUG: 14C-LY2140023|DRUG: 14C-LY404039
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Altreno for Chest Rejuvenation
Status: UNKNOWN
Conditions: Photodamaged Skin|Photoaging
Interventions: DRUG: tretinoin 0.05% lotion (Altreno)|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Surgery With or Without Chemotherapy for Stage I NSCLC With Micropapillary Component ≥ 20%
Status: RECRUITING
Conditions: Chemotherapy, Adjuvant|Lung Adenocarcinoma, Stage I|Treatment|Histological Type of Neoplasm
Interventions: DRUG: cis Platinum/Carboplatin, Pemetrexed Disodium|PROCEDURE: Undergo surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of LX22001 for Injection in Healthy Subjects
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: LX22001 for Injeciton|DRUG: Tegoprazan tablet|DRUG: Esomeprazole sodium for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Joint Management of DM2 and Pulmonary TB in Orizaba, Veracruz
Status: WITHDRAWN
Conditions: Pulmonary Tuberculosis|Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Community intervention|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Breathing a Mixture of 92% Oxygen (O2) + 8% Carbon Dioxide (CO2) on Flicker Induced Blood Flow Changes in Ocular Perfusion
Status: COMPLETED
Conditions: Flicker-induced Vasodilatation
Interventions: DRUG: Oxygen + Carbondioxide|OTHER: full field flickering light at 12.5 Hz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: IL-11 in Women With Von Willebrand Disease and Refractory Menorrhagia
Status: COMPLETED
Conditions: Von Willebrand Disease
Interventions: DRUG: Oprelvekin, Interleukin 11, IL-11
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of Chinese Medicine Plus Chemotherapy Maintenance in Advanced Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: YiQiFang|DRUG: YangYinFang|DRUG: YiQiYangYinFang|DRUG: Gemcitabine®|DRUG: Pemetrexed®|DRUG: Docetaxel®|DRUG: placebo granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VitaFlow™ Transcatheter Aortic Valve System Pre-market Trial
Status: UNKNOWN
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: VitaFlow™ Transcatheter Aortic Valve System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dexamethasone 12 mg vs 6 mg on Thromboembolic Events in Patients With Critical COVID-19
Status: COMPLETED
Conditions: COVID-19|Thrombosis Embolism|Bleeding
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT