pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Sunitinib Malate Schedule 4/2 vs. Sunitinib Malate Continuous Dosing As First-Line Therapy For Metastatic Renal Cell Cancer (RCC)
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Sunitinib Malate Continuous Daily Dosing|DRUG: Sunitinib Malate Schedule 4/2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of DS-6000a in Subjects With Advanced Renal Cell Carcinoma and Ovarian Tumors
Status: RECRUITING
Conditions: Renal Cell Carcinoma|Ovarian Tumor
Interventions: DRUG: DS-6000a|DRUG: DS-6000a
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: WB-EMS and Nutrition in Patients With Hematological Malignancies
Status: UNKNOWN
Conditions: Hematologic Diseases|Cachexia; Cancer|Leukemia|Myeloma|Lymphoma|Cancer
Interventions: OTHER: whole-body electromyostimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparative Study to Measure the Effect of Nebulized Dexmedetomidine
Status: UNKNOWN
Conditions: Dexmedetomidine|Lidocaine|Tonsillectomy
Interventions: DRUG: Dexmedetomidine Hydrochloride|DRUG: Nebulized lidocaine|DRUG: Local infiltration of lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Darbepoetin Alfa Dosing for the Correction of Anemia in Pediatric Patients With Chronic Kidney Disease
Status: TERMINATED
Conditions: Anemia|Chronic Kidney Disease|Kidney Disease
Interventions: DRUG: Darbepoetin Alfa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Standardized Physician-modified Fenestrated Endograft Registry
Status: RECRUITING
Conditions: Aortic Aneurysm, Thoracoabdominal|Aortic Diseases
Interventions: DEVICE: Physician-modification of Valiant Captivia Endograft (Medtronic, Minneapolis, MN-USA).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults
Status: COMPLETED
Conditions: Participants With or Without Stable Co-morbidities Associated With Progression to Severe COVID-19
Interventions: BIOLOGICAL: Ad26.COV2.S|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase III Study to Assess the Efficacy and Safety of Almonertinib Versus Platinum-based Chemotherapy as First-line Therapy in Patients With Locally Advanced or Metastatic NSCLC Harbouring Uncommon EGFR Mutation
Status: NOT_YET_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Almonertinib|DRUG: chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlled Study of MK-0431/ONO-5435 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Placebo|DRUG: Sitagliptin phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radioimmunotherapy With or Without Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Thyroid Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: doxorubicin hydrochloride|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: indium In 111 monoclonal antibody MN-14|RADIATION: yttrium Y 90 monoclonal antibody MN-14
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of RO6953958 in Healthy Participants
Status: COMPLETED
Conditions: Autistic Disorder|Autism Spectrum Disorder|Child Development Disorders, Pervasive|Mental Disorders|Neurodevelopmental Disorders
Interventions: DRUG: RO6953958|DRUG: Placebo|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adequacy of Exsanguination Between Esmarch Bandages and Simple Leg Elevation in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Esmarch Bandages|Simple Leg Elevation
Interventions: OTHER: Esmarch bandages|OTHER: simple leg elevation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Explorative Study of AZD1305 in Atrial Fibrillation Patients
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: AZD1305|DRUG: AZD1305|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Risk in Cardiac Rehabilitation: Partners Together in Health (PaTH) Intervention Study
Status: COMPLETED
Conditions: Coronary Heart Disease|Cardiac Rehabilitation
Interventions: BEHAVIORAL: Partners Together in Health (PaTH) Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AMPLATZER™ Amulet™ LAA Occluder Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke
Interventions: DEVICE: Amulet Left Atrial Appendage Occluder|DEVICE: WATCHMAN Left Atrial Appendage Closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Walnuts, Long-Chain Polyunsaturated Fatty Acids and Adolescent Brain Development
Status: COMPLETED
Conditions: Vitamin/Nutritional Deficiency|Neurobehavioral Manifestations
Interventions: DIETARY_SUPPLEMENT: Walnut intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Compare the Safety and Tolerability of Sativex® in Patients With Cancer Related Pain
Status: COMPLETED
Conditions: Pain|Cancer
Interventions: DRUG: Sativex|DRUG: GW-2000-02
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of High Frequency Chest Compression in Pediatric Status Asthmaticus
Status: TERMINATED
Conditions: Pediatric, Asthma, Acute Exacerbation, Pediatric ICU
Interventions: DEVICE: High Frequency Chest Compression VEST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Self-management Education Based on Theory of Planned Behavior on Patients With Type 2 Diabetes
Status: SUSPENDED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Self-management education|BEHAVIORAL: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Click2Print Artificial Eyes
Status: COMPLETED
Conditions: Enucleated; Eye|Evisceration; Traumatic, Eye
Interventions: DEVICE: Click2Print artificial eye|DEVICE: Hand-made artificial eye
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fase II Study With BRB for Non-Hodgkin Lymphoplasmacytic Lymphoma/Waldenstrom Macroglobulinemia's
Status: COMPLETED
Conditions: Waldenstrom's Macroglobulinemia
Interventions: DRUG: Bortezomib-Rituximab-Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of TACE Plus PD-1 Antibody in the Locally Advanced Stomach Adenocarcinoma
Status: RECRUITING
Conditions: Advanced Gastric Cancer
Interventions: DRUG: Transcatheter Arterial Chemoembolization|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of tDCS on Cognition in MCI: A RCT
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cognitive Behavioral Therapy Education to Elderly Care Students on Outcome Measures
Status: COMPLETED
Conditions: Cognitive Behavioral Therapy|Ageism
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Two Intraocular Gas Injection Techniques in Macula Hole Surgery
Status: COMPLETED
Conditions: Macular Holes
Interventions: DRUG: small amount of undiluted C3F8
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can Dexmedetomidine With Hyalase Augment Quality and Duration of Analgesia When Added to Lumbar Epidural Steroid in Failed Back Surgery. Randomized Double Blind Study
Status: UNKNOWN
Conditions: Pain, Neuropathic
Interventions: DRUG: Hylase plus Triamcinolone plus sterile isotonic saline|DRUG: Hylase plus Dexmedetomidine plus Triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of SHR-A1811 Combined With Other Antitumor Therapies in Advanced Solid Tumors.
Status: RECRUITING
Conditions: HER2-expressing Advanced Solid Tumors
Interventions: DRUG: SHR-A1811 combined with Pyrotinib.|DRUG: SHR-A1811 combined with other antitumor therapies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Normovolemic Hemodilution Versus Standard Intraoperative Management in Patients Having Hepatic Resection and Pancreaticoduodenectomy
Status: COMPLETED
Conditions: Pancreaticoduodenectomy|Hepatectomy
Interventions: PROCEDURE: Normovolemic Hemodilution (ANH)|PROCEDURE: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Single Day of Mixed Macronutrient Overfeeding on Energy Balance and Metabolic Responses
Status: COMPLETED
Conditions: Metabolic Disease|Appetitive Behavior
Interventions: OTHER: Overfeed|OTHER: Energy Balance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of Neurofeedback for the Treatment of Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: OTHER: Training with Neurofeedback|OTHER: The other Training with Neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utility of Indocyanine Green Fluorescence in Endoscopic Sinonasal and Skull Base Surgery
Status: NOT_YET_RECRUITING
Conditions: Chronic Sinusitis|Tumor of Nasal Sinus|Posterior Epistaxis|Skull Base Neoplasms
Interventions: PROCEDURE: Sinonasal Benign or Malignant Tumor Resection|PROCEDURE: Skull Base Surgery (Assessment of Nasoseptal Flap)|PROCEDURE: Endoscopic Sinus Surgery|PROCEDURE: Posterior Epistaxis Management (SPA Ligation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of the Improvement and Safety of the Ankle Brachial Arterial Pressure Index of Sarpogrelate and Clopidogrel in Stroke Patients With Decreased Ankle Brachial Arterial Pressure Index and Intermittent Claudication of Lower Limb Vascular Atherosclerosis.
Status: NOT_YET_RECRUITING
Conditions: Stroke|Atherosclerosis
Interventions: DRUG: Administration of Sarpogrelate|DRUG: Traditional administration of Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of DHA on Pro-resolving Anti-inflammatory Mediators in Obese Patients Undergoing Weight-loss Treatment
Status: COMPLETED
Conditions: Obesity|Inflammation
Interventions: DIETARY_SUPPLEMENT: Omega-3 DHA|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Moderate Mitral Regurgitation in CABG Patients
Status: UNKNOWN
Conditions: Moderate Mitral Regurgitation
Interventions: PROCEDURE: CABG alone|PROCEDURE: CABG + Mitral repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CIMT and Plaque Assessment Findings in Subjects Undergoing Stress Echocardiography For Risk Stratification
Status: COMPLETED
Conditions: Cardiovascular Risk Stratification|Carotid Intima-media Thickness (CIMT)|Stress Echocardiography (SE)
Interventions: OTHER: Carotid Intima-Media Thickness (CIMT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The ENDEAVOR II Clinical Trial: The Medtronic Endeavor Drug Eluting Coronary Stent System in Coronary Artery Lesions
Status: COMPLETED
Conditions: Coronary Artery Disease|Arterial Occlusive Diseases|Coronary Disease|Coronary Arteriosclerosis|Heart Diseases|Myocardial Ischemia|Vascular Diseases|Ischemia|Arteriosclerosis
Interventions: DEVICE: Endeavor drug eluting coronary stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Atazanavir-induced Hyperbilirubinemia During Human Endotoxemia
Status: COMPLETED
Conditions: Endotoxemia|Inflammation|Multi Organ Dysfunction Syndrome|Sepsis
Interventions: DRUG: Atazanavir|DRUG: E. coli endotoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Simplus and Eson Non-Invasive Ventilation (NIV) Evaluation - Germany
Status: TERMINATED
Conditions: Obesity Hypoventilation Syndrome|Obstructive Sleep Apnea|Chronic Obstructive Pulmonary Disease|Neuromuscular Disease
Interventions: DEVICE: Simplus/Eson
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wound Protector Dual-ring Alexis® in Pancreaticoduodenectomy
Status: TERMINATED
Conditions: Surgical Site Infection
Interventions: DEVICE: Alexis|DEVICE: Standard 3M™ Steri-Drape 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cryoablation in Patients With Atrial Flutter
Status: UNKNOWN
Conditions: Atrial Flutter
Interventions: PROCEDURE: Cryoballoon ablation|PROCEDURE: Implantation of loop recorder|PROCEDURE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of a Visio-Hearing Training Protocol on Spatial Hearing in Subjects With Hearing Loss
Status: COMPLETED
Conditions: Cochlear Nerve Deafness|Cochlear Diseases|Cochlear Hearing Loss|Hearing Loss|Deafness
Interventions: BEHAVIORAL: Training Protocol n°1 first at Visit 1, then, Training Protocol n°2 at Visit 2|BEHAVIORAL: Training Protocol n°2 first at Visit 1, then, Training Protocol n°1 at Visit 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study on the Reduction of Catheter-related Infections by Use of Self-disinfecting Venous and Arterial Access Caps
Status: COMPLETED
Conditions: CLABSI - Central Line Associated Bloodstream Infection|Catheter-Related Blood Stream Infection
Interventions: DEVICE: 70% isopropyl alcohol-impregnated catheter caps
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility Study: IGNITE-TX (Identifying Individuals for Genetic Testing & Treatment) Intervention
Status: RECRUITING
Conditions: Gynecologic Cancer|Ovary Cancer|Pancreatic Cancer|Breast Cancer|Lynch Syndrome|Hereditary Breast and Ovarian Cancer Syndrome|Colon Cancer|Endometrial Cancer|Uterus Cancer
Interventions: BEHAVIORAL: Free genetic testing and counseling group|BEHAVIORAL: IGNITE-TX Group|BEHAVIORAL: IGNITE-TX and free genetic testing and counseling group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Oncoxin-Viusid® in Cutaneous Melanoma
Status: COMPLETED
Conditions: Cutaneous Melanoma, Stage II|Malignant Cutaneous Melanoma|Cutaneous Melanoma, Stage III
Interventions: DIETARY_SUPPLEMENT: Oncoxin-Viusid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Study With Oxaliplatin in 2nd Line Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: DRUG: Leucovorin|DRUG: OXALIPLATIN|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Esmolol Versus Dexmedetomidine on Postoperative Pain Control in Endoscopic Sinus Surgery: A Randomized Trial
Status: RECRUITING
Conditions: Patient's Satisfaction|Depth of Anesthesia
Interventions: DRUG: Esmolol Esterase|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Two Protocols to Improve Reflex Integration and Functional Performance
Status: ACTIVE_NOT_RECRUITING
Conditions: Developmental Delay
Interventions: OTHER: Fine and gross motor treatment only|OTHER: Reflex integration + fine and gross motor treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Increased Activity of ENaC in Proteinuric Kidney Transplant Recipients
Status: COMPLETED
Conditions: Kidney Transplant; Complications
Interventions: DIETARY_SUPPLEMENT: Standardized sodium diet|DRUG: Tbl amiloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intra-op POCUS for Identification of Endotracheal Tube Position in the Pediatric Population
Status: COMPLETED
Conditions: Endotracheal Tube Wrongly Placed During Anesthetic Procedure
Interventions: DEVICE: Point-of-care ultrasound exam|RADIATION: Reposition ETT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Patients With Major Depressive Disorder With MK0869 (0869-068)(COMPLETED)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: aprepitant|DRUG: Comparator: placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial Comparing Short Versus Long Oesophageal Myotomy in POEM for Achalasia Cardia.
Status: COMPLETED
Conditions: Achalasia Cardia
Interventions: PROCEDURE: Per oral endoscopic myotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Establishing Normative Values for Thermal Detection and Pain Threshold Established by the Psi Method
Status: SUSPENDED
Conditions: Small Fiber Neuropathy
Interventions: DIAGNOSTIC_TEST: Thermal QST (CDT, WDT, CPT, HPT) with the method of limits|DIAGNOSTIC_TEST: Thermal QST (cold and warm detection, heat pain) with the psi method|DIAGNOSTIC_TEST: Neurological examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating ActionADE on Adverse Drug Event Due to Non-Adherence
Status: UNKNOWN
Conditions: Adverse Drug Event|Non-Adherence, Medication
Interventions: DEVICE: ActionADE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Distribution of Neutrophils in Bronchial Mucosal Tissue in Asthma Patients Before and After 4 Weeks Treatment With AZD 5069
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: AZD5069
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Study of CPX-351 (VYXEOS) in Individuals < 22 Years With Secondary Myeloid Neoplasms
Status: RECRUITING
Conditions: Myeloid Neoplasm
Interventions: DRUG: CPX-351|DRUG: MHA|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Initial Assessment of a Topical Cadexomer Iodine Gel Efficacy on Keloid Scar Revision
Status: WITHDRAWN
Conditions: Keloid Scar Following Surgery
Interventions: DEVICE: Cadexomer Iodine Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Heart Cycle GEx (Guided- Exercise- Main Trial)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Guide Exercise (GEx-)- Training|DEVICE: Guided Exercise Training with an easy to wear vest with electrodes to measure ECG, respiration, activity|DEVICE: Control group training without Guided Exercise system at home
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Triptorelin (Decapeptyl®) 22.5 mg on Two Biomarkers in Patients With Advanced Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Triptorelin (Decapeptyl®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Transpalpebral Micro-Current Electrical Stimulation for the Treatment of Dry Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Age-Related (Dry) Macular Degeneration
Interventions: DEVICE: Nova Oculus™ Micro-current electrical stimulation|DEVICE: Nova Oculus™ Micro-current electrical stimulation - Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Stoma Discharge Reinfusion After Sphincter Preservation for Middle and Low Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Rectal Cancer
Interventions: PROCEDURE: stoma drainage reinfusion|PROCEDURE: Standard of Care - No Return of Stoma Drain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gallium (68Ga) Edotreotide PET/CT for Imaging Patients With Gastrointestinal Pancreatic Neuroendocrine Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Gastroenteropancreatic Neuroendocrine Tumor
Interventions: DRUG: 68Ga-DOTATOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Access Efficacy and Safety of P1101 in Chinese PV Patients Who Are Intolerant or Resistance to HU
Status: ACTIVE_NOT_RECRUITING
Conditions: Polycythemia Vera
Interventions: DRUG: Ropeginterferon alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Krill Oil Supplementation on Red Blood Cell Physiology Against Changes in Markers of Iron Metabolism.
Status: RECRUITING
Conditions: Red Blood Cell Disorder|Oxidative Stress|Iron Metabolism Disorders
Interventions: DRUG: THYROX (Atlantic krill oil).|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Investigator Initiated, Within-Subject, Proof of Concept Study to Assess the Efficacy and Safety of Voltaren Gel in Subjects With DOMS
Status: COMPLETED
Conditions: Pain|Delayed Onset Muscle Soreness
Interventions: DRUG: 1% diclofenac sodium gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of 68Ga-DOTATATE PET/CT on the Management of Neuroendocrine Tumors: The Referring Physician's Perspective
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: 68Ga-DOTATATE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Carbon-14-Labelled [14C] LY3372689 in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [¹⁴C]-LY3372689
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Training on the Use of Software and Digital Monitoring Tools During General Anesthesia for Intermediate/Major-risk Surgery on Morbidity and Mortality at 28 Days
Status: RECRUITING
Conditions: All Conditions Requiring Non-cardiac Surgery
Interventions: OTHER: Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation Study for Assessing the Visual Performance of Hanita Lenses Trifocal IOL
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: cataract surgery and intraocular lens implantation - both eyes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Endovascular Inferior Mesenteric Artery Embolization on Colonic Perfusion Prior to Rectal Surgery for Rectal Tumor or Sigmoid Colon Surgery
Status: COMPLETED
Conditions: Cancer, Sigmoid|Cancer, Rectum
Interventions: PROCEDURE: embolization of the inferior mesenteric artery|PROCEDURE: Inferior mesenteric artery ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Lung Ultrasound Score and Pediatric Intensive Care Outcomes (LUS-PICO)
Status: COMPLETED
Conditions: Lung Injury|Extravascular Lung Water|Pulmonary Edema|Acute Respiratory Distress Syndrome|Shock
Interventions: DIAGNOSTIC_TEST: Bedside lung ultrasound examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: N-Acetylcysteine as an Adjunct for Refractory Chronic Suppurative Otitis Media
Status: WITHDRAWN
Conditions: Otitis Media|Otorrhea
Interventions: DRUG: Ciprodex|DRUG: Ciprodex and 2% NAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Selenium for Musculoskeletal Health
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DIETARY_SUPPLEMENT: selenase (selenium)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and Pharmacokinetic Study of Allegra in Pediatric Patients With Atopic Dermatitis (AD)
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: fexofenadine/Allegra (M016455)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy, and Frequency of Administration of VNX001 in the Treatment of Interstitial Cystitis / Bladder Pain Syndrome (IC/BPS)
Status: NOT_YET_RECRUITING
Conditions: Interstitial Cystitis|Bladder Pain Syndrome
Interventions: DRUG: VNX001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Testosterone to Prevent Post-Surgical Muscle Loss - Pilot Study
Status: UNKNOWN
Conditions: Muscle Atrophy|Surgery|Knee Injuries and Disorders|Complication of Surgical Procedure|Trauma
Interventions: DRUG: Aveed 750 MG in 3 ML IM Injection|OTHER: Normal Saline 3 ML IM Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: North American Study of Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT)
Status: COMPLETED
Conditions: Telangiectasia, Hereditary Hemorrhagic|Epistaxis
Interventions: DRUG: Sterile saline|DRUG: Bevacizumab|DRUG: Estriol|DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Performance and Safety of the Medical Device Auralya® in the Treatment of Facial Dermal Tissue Defects
Status: UNKNOWN
Conditions: Cicatrix|Lipodystrophy|Plaque
Interventions: DEVICE: Auralya
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple Health Behavior Change Intervention for Overweight and Obese Smokers
Status: COMPLETED
Conditions: Smoking Cessation|Obesity
Interventions: BEHAVIORAL: Self-Regulation strategies + large changes (SR)|BEHAVIORAL: Healthy Lifestyle Education (LE)|OTHER: Smoking Cessation Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Actovegin® Versus Placebo in Patients With Diabetic Polyneuropathy (AV-007-IM)
Status: COMPLETED
Conditions: Symptomatic Diabetic Peripheral Polyneuropathy
Interventions: DRUG: Deproteinised hemoderivative of calf blood (Actovegin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of CKDB-501B in Subjects With Moderate-to-severe Glabellar Lines
Status: COMPLETED
Conditions: Glabellar Lines
Interventions: DRUG: CKDB-501B|DRUG: Botox®50U
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exenatide Compared With Insulin Glargine to Change Liver Fat Content in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Non-alcoholic Fatty Liver Disease
Interventions: DRUG: Exenatide|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Nurse Led Project to Introduce Hand Lettering as a Form of Creative Art Expression to Patients in an Ambulatory Oncology Setting
Status: COMPLETED
Conditions: Anxiety
Interventions: BEHAVIORAL: Breathing and journaling exercise|OTHER: Art-therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Comparing Muraglitazar With Glimepiride in Type 2 Diabetics Who Are Not Controlled With Metformin Alone
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: muraglitazar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate ALDOXORUBICIN in HIV-infected Subjects With Kaposi's Sarcoma
Status: COMPLETED
Conditions: Kaposi's Sarcoma|HIV Positive|AIDS
Interventions: DRUG: 50 mg/m2 aldoxorubicin|DRUG: 100 mg/m2 aldoxorubicin|DRUG: 150 mg/m2 aldoxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-inferiority of Short-term Catheterization Following Fistula Repair Surgery
Status: COMPLETED
Conditions: Vaginal Fistula
Interventions: PROCEDURE: 7-day catheterization following fistula repair surgery|PROCEDURE: 14 day catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin or B-CAP in the Treatment of Older Patients With Newly Diagnosed Classical Hodgkin Lymphoma
Status: COMPLETED
Conditions: Hodgkin Lymphoma
Interventions: DRUG: B-CAP|DRUG: Brentuximab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging of Lymphatic Vessels in People With Rheumatoid Arthritis (RA)
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Indocyanine green|DEVICE: MultiSpectral Imaging System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Two Different Techniques of Synovial Biopsy and Resistances of Cutaneous Smears in Suspected PPI
Status: UNKNOWN
Conditions: Infection of Total Knee Joint Prosthesis
Interventions: PROCEDURE: synovial biopsy of total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Infusion of 5-Azacytidine (5-AZA) Into the Fourth Ventricle in Patients With Recurrent Posterior Fossa Ependymoma
Status: RECRUITING
Conditions: Recurrent Ependymoma
Interventions: DRUG: 5-Azacytidine (5-AZA) group 1|DRUG: 5-Azacytidine (5-AZA) group 2|DRUG: 5-Azacytidine (5-AZA) group 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of BI 655075 Administered Alone or With Dabigatran Etexilate
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dabigatran|DRUG: BI 655075|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Camp NERF: Methods of a Summer Nutrition Ed Rec & Fitness Program to Prevent Unhealthy Weight Gain in Children
Status: COMPLETED
Conditions: Childhood Obesity
Interventions: BEHAVIORAL: Enhanced Care|BEHAVIORAL: Standard Care|BEHAVIORAL: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Irritation and Anal Bleeding in Patients Affected by Hemorrhoids.
Status: UNKNOWN
Conditions: Hemorrhoids
Interventions: DRUG: flavonoid-based supplements|DRUG: Centella Complex|BEHAVIORAL: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Pharmacokinetics of Brachial Plexus Block With EXPAREL in Shoulder Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: bupivacaine liposome injectable suspension|DRUG: bupivacaine liposome injectable suspension|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cholecalciferol on Hemodialysis Patients
Status: COMPLETED
Conditions: Hemodialysis Complication|Vitamin D Deficiency|Vascular Calcification
Interventions: DRUG: Cholecalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Community Health Worker-Led LSSS Intervention in Bangladesh
Status: RECRUITING
Conditions: Blood Pressure|Hypertension
Interventions: DIETARY_SUPPLEMENT: Low-Sodium Salt Substitute|BEHAVIORAL: Information/Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Program of Evaluation and Geriatric Intervention on the Functional Status, Quality of the Life, and Survival
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: BEHAVIORAL: WITH Comprehensive Geriatric assessment|BEHAVIORAL: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cognitive Rehabilitation and Brain Activity of Attention-Control Impairment in TBI
Status: WITHDRAWN
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: BrainHQ|BEHAVIORAL: Goal Management Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Total-Body Irradiation and Chemotherapy Followed By Donor Bone Marrow Transplant in Treating Young Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|DRUG: thiotepa|PROCEDURE: allogeneic bone marrow transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of FSH Dosage During Ovarian Stimulation for IVF/ICSI in Granulosa Cells
Status: COMPLETED
Conditions: Ovarian Function Insufficiency|Fertility Issues|Infertility,Female|Infertility
Interventions: DRUG: Follitropin beta injection 150 IU|DRUG: Follitropin beta injection 300 IU
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Paclitaxel|DRUG: Irinotecan|BIOLOGICAL: Pembrolizumab|BIOLOGICAL: MK-4830|DRUG: Lenvatinib|BIOLOGICAL: Sacituzumab tirumotecan|DRUG: Antihistamine|DRUG: H2 Receptor Antagonist|DRUG: Acetaminophen (or equivalent)|DRUG: Dexamethasone (or equivalent)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thermal Therapy for the Treatment of Depression in Cancer Survivors, the S-WARM Study
Status: WITHDRAWN
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|PROCEDURE: Thermotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study to Study PQ-110-001 (NCT03140969)
Status: TERMINATED
Conditions: Leber Congenital Amaurosis 10|Blindness|Leber Congenital Amaurosis|Vision Disorders|Sensation Disorders|Neurologic Manifestations|Eye Diseases|Eye Diseases, Hereditary|Eye Disorders Congenital|Retinal Disease
Interventions: DRUG: QR-110
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination ± Ribavirin for the Treatment of HCV (ION-3)
Status: COMPLETED
Conditions: Chronic Hepatitis C Virus
Interventions: DRUG: LDV/SOF|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Ethanol on Oxycodone Pharmacokinetics in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Oxycodone|DRUG: Naltrexone|DRUG: Oxycodone|DRUG: Naltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Management of Glucose Control and Hypoglycemic Prevention Using Continuous Glucose Monitoring System in Patients With Type 1 Diabetes
Status: UNKNOWN
Conditions: Type 1 Diabetes
Interventions: DEVICE: Continuous glucose monitoring system(CGMS)|DEVICE: Self-monitoring of blood glucose (conventional fingerpricking method)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Airway Clearance Devices in ALS
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DEVICE: High Frequency Chest Compression Device (HFCC)|DEVICE: Cough Assist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of INCMGA00012, INCB001158, and the Combination in Japanese Participants With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors|Metastatic Solid Tumors
Interventions: DRUG: Retifanlimab|DRUG: INCB001158|DRUG: Retifanlimab + INCB001158
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systemic Absorption of Dexamethasone Oral Rinse in Patients With Oral Lichen Planus
Status: NOT_YET_RECRUITING
Conditions: Oral Lichen Planus|Oral Lichenoid Reaction
Interventions: DRUG: dexamethasone oral rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Daily Disposable Contact Lenses
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: filcon II 3|DEVICE: etafilcon A|DEVICE: nelfilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Optimal Location of Local Anesthetic Injection for Ultrasound Guided Interscalene Block
Status: COMPLETED
Conditions: Shoulder Arthroscopy|Ultrasound-guided Interscalene Nerve Block
Interventions: PROCEDURE: Interscalene block for shoulder arthroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Creatine Supplementation on Cognition in Children
Status: UNKNOWN
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: creatine supplementation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Online Intervention Targeting Cancer-related Fatigue
Status: TERMINATED
Conditions: Cancer Survivor|Malignant Neoplasm
Interventions: OTHER: Internet-Based Intervention|OTHER: Internet-Based Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Escitalopram to Placebo in Patients With Localized Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Ductal Adenocarcinoma|Periampullary Cancer
Interventions: DRUG: Escitalopram|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Placebo Controlled Study for Characterisation of Immunological Effects and Safety of Active O2
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Active O2|OTHER: Adelholzener Mineralwasser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bicarbonate for In-Hospital Cardiac Arrest
Status: RECRUITING
Conditions: Cardiac Arrest
Interventions: DRUG: Sodium bicarbonate|DRUG: Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Two Physical Therapy Treatments in Patients With Nonspecific Chronic Neck Pain
Status: COMPLETED
Conditions: Non-specific Chronic Neck Pain
Interventions: OTHER: Active physical therapy (including both pain education and home exercises)|OTHER: Active physical therapy plus manual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medical Economics of Urinary PCA3 Test for Prostate Cancer Diagnosis
Status: COMPLETED
Conditions: Patients Scheduled for Prostate Biopsy Because of Increased Serum PSA and/or Abnormal Digital Rectal Examination
Interventions: OTHER: urinary PCA3 test using Progensa® PCA3 assay kit (Gen-Probe)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Impact of Teacher Nonverbal Behaviors on Children's Intergroup Attitudes and Mental Health
Status: COMPLETED
Conditions: Stress, Psychological|Stress, Emotional
Interventions: BEHAVIORAL: Assigned to positive group|BEHAVIORAL: Assigned to negative group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE