pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety Comparison of Niraparib to Placebo in Participants With Human Epidermal Growth Factor 2 Negative (HER2-) Breast Cancer Susceptibility Gene Mutation (BRCAmut) or Triple-Negative Breast Cancer (TNBC) With Molecular Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoplasms, Breast
Interventions: DRUG: Niraparib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Injury Coping Skills - Telemedicine: Phase II
Status: COMPLETED
Conditions: Traumatic Brain Injury|Coping Skills|Caregivers
Interventions: BEHAVIORAL: Brain Injur Coping Skills - Telemedicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Outcomes Between Low Dose Emicizumab and Factor VIII in Clinically Severe Hemophilia A
Status: RECRUITING
Conditions: Severe Hemophilia A Without Inhibitor|Joint Bleed
Interventions: DRUG: "Emicizumab", "HEMLIBRA®"
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Osteomyelitis Using High Resolution Ultrasound
Status: UNKNOWN
Conditions: Chronic Osteomyelitis
Interventions: DEVICE: Hitachi-Aloka Noblus ultrasound scanner|DEVICE: Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Evolocumab in Addition to Optimal Stable Background Statin Therapy in Chinese Participants With Primary Hypercholesterolemia and Mixed Dyslipidemia
Status: TERMINATED
Conditions: Primary Hypercholesterolemia|Mixed Dyslipidemia
Interventions: DRUG: evolocumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Periocline as an Adjunct to Scaling and Root Planing for Adult Periodontitis
Status: COMPLETED
Conditions: Adult Periodontitis
Interventions: DRUG: minocycline HCl 2.1%|PROCEDURE: Scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ILX651 in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Carcinoma
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: DRUG: ILX651
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Simulator Based (PickUpSimTM) Residents' Training Program for Oocyte Retrievals
Status: UNKNOWN
Conditions: Infertility|Oocytes|Fertilization in Vitro
Interventions: PROCEDURE: PickUpSimTM simulation training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: WASH Benefits Child Development Follow up
Status: UNKNOWN
Conditions: Child Development|Maternal Depression
Interventions: BEHAVIORAL: Water quality|BEHAVIORAL: Sanitation|BEHAVIORAL: Hand washing|BEHAVIORAL: Water quality, Sanitation, Hand washing (Combined WASH)|BEHAVIORAL: Nutrition|BEHAVIORAL: Nutrition, Water quality, Sanitation, Hand washing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Salvage mFOLFOX in BTC After Failure of Gemcitabine
Status: COMPLETED
Conditions: Unresectable Biliary Tract Cancer
Interventions: DRUG: 5-fluorouracil, leucovorin, oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Canadian Community Utilization of Stroke Prevention Study - Emergency Department
Status: COMPLETED
Conditions: Atrial Fibrillation|Stroke
Interventions: OTHER: Retrospective review of OAC prescription|OTHER: Prescription of OAC in ED|OTHER: Community AF clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Diluting With Cerebrospinal Fluid Versus Traditional Intrathecal Administration: Antishivering Effects
Status: WITHDRAWN
Conditions: Antishivering Effects
Interventions: PROCEDURE: bupivacaine 0.5% 2.5 mL diluting with cerebrospinal fluid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety Study of Abiraterone Acetate Administered in Combination With Docetaxel in Patients With Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Status: COMPLETED
Conditions: Prostate Neoplasms|Prostate Cancer
Interventions: DRUG: Cohort 4|DRUG: Cohort 3|DRUG: Cohort 2|DRUG: Cohort 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Basket Trial in Which Patients With Advanced Solid Tumors Carrying the KRAS G12C mUtation Receive Treatment With a Combination of Sotorasib and Panitumumab
Status: ACTIVE_NOT_RECRUITING
Conditions: Efficacy
Interventions: DRUG: Oral sotorasib + IV Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Multi-dose of HB0034 in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Recombinant Humanized Anti-IL-36R Monoclonal antibody and Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of Combined Aerobic and Strength Training in Acute and Chronic Adaptations in Patients With Heart Failure
Status: COMPLETED
Conditions: Chronic Heart Failure|Fragility
Interventions: OTHER: Combined Aerobic Training|OTHER: Combined Strength Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Liquid Bovine Rotavirus Pentavalent Vaccine (LBRV-PV) to Evaluate Lot-to-Lot Consistency and to Compare Non-Inferiority With ROTASIIL (Lyophilized BRV-PV) in Healthy Infants in India
Status: COMPLETED
Conditions: Rotavirus Gastroenteritis
Interventions: BIOLOGICAL: Liquid Rotavirus Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Diffusion of Oxygen Treatment for Incision Wounds
Status: RECRUITING
Conditions: Surgical Wound|Breast Surgery|Mammoplasty|Incision Wound
Interventions: DEVICE: Transcu O2®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Study of AzaSite Plus Compared to AzaSite Alone and Dexamethasone Alone to Treat Subjects With Blepharoconjunctivitis
Status: COMPLETED
Conditions: Blepharoconjunctivitis
Interventions: DRUG: 1% Azithromycin and 0.1% Dexamethasone|DRUG: 1% Azithromycin|DRUG: 0.1% Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Young Patients Who Are Undergoing Surgery and an Autologous Bone Marrow Transplant for Disseminated Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: carboplatin|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: melphalan|DRUG: vincristine sulfate|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Eribulin Mesylate Combined With Lobaplatin in the Treatment of Recurrent or Metastatic Triple-negative Breast Cancer
Status: UNKNOWN
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Eribulin Mesylate|DRUG: Lobaplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fimasartan in the Senior Subjects
Status: COMPLETED
Conditions: The Elderly (≥ 70 Years) With Essential Hypertension
Interventions: DRUG: Fimasartan or Fimasartan/Hydrochlorothiazide|DRUG: Perindopril or Perindopril/Indapamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Comfort of Lubricant Eye Drops FID 112903
Status: COMPLETED
Conditions: Dry Eye
Interventions: OTHER: Lubricant Eye Drops FID 112903|OTHER: Optive Lubricant Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Evaluation by Ultrasound Radiofrequency Echographic Multi Spectrometry (REMS) vs Dual X-ray Absorptiometry (DXA)
Status: RECRUITING
Conditions: Osteoporosis Diagnosis
Interventions: DEVICE: Ultrasound examination with REMS technology
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sleep in Psychiatric Care (SIP): Treatment for Comorbid Delayed Sleep-Wake Phase Disorder (DSWPD)
Status: RECRUITING
Conditions: Delayed Sleep-Wake Phase Disorder|Sleep Disorder|Psychiatric Disorder
Interventions: BEHAVIORAL: Group-based light therapy at gradually advanced timing for DSWPD|BEHAVIORAL: Group-based light therapy at gradually advanced timing for DSWPD and additive bb-glasses|OTHER: 6-week wait list for sleep-school
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Acupuncture for Pain, Opioid Use Disorder and Mood
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain|Opioid Use Disorder|Mood Change|Opioid Misuse|Opioid-Related Disorders
Interventions: DEVICE: Modified Battlefield Acupuncture + National Acupuncture Detoxification Association protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Anti-Hemagglutinin (Anti-HA) Antibodies as Protection From the Flu in Healthy People
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Ca/04/2009/H1N1r Challenge Virus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparison of Visual Function After Bilateral Implantation of Presbyopia Correcting Intraocular Lenses
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: ReSTOR +3|DEVICE: LENTIS MPlus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Exploring 8-iso Prostaglandin F2α and Adenosine Deaminase Levels in Periodontal Health and Disease
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: DIAGNOSTIC_TEST: 8-iso Prostaglandin F2α and Adenosine Deaminase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of VentiBroncTM Anchor With Conventional Double-lumen Endobronchial Tube in Patients With High Risk of Malposition
Status: RECRUITING
Conditions: Endotracheal Intubation
Interventions: DEVICE: Intubation with VentiBronc Anchor endobronchial double-lumen tube|DEVICE: conventional double-lumen intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Extension Study of Enteric-coated Mycophenolate Sodium With Short-term or no Steroid Use Compared With Enteric-coated Mycophenolate Sodium With Standard Steroid Therapy in de Novo Kidney Recipients
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: DRUG: Enteric-coated Mycophenolate sodium (EC-MPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Prophylactic Antibiotic Duration in Moderate to High Risk Ureteroscopy
Status: NOT_YET_RECRUITING
Conditions: Infections, Urinary Tract|Nephrolithiasis
Interventions: OTHER: Duration of antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Thyroid Hormone Replacement for Secondary Hypothyroidism Following Intracerebral Hemorrhage
Status: RECRUITING
Conditions: Intracerebral Hemorrhage|Low T3 Syndrome|Neurocritical Care|Hormone Replacement Therapy
Interventions: DRUG: Euthyrox|DRUG: Euthyrox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Anaferon for Children Efficacy in Prevention of Influenza and Other ARVI
Status: COMPLETED
Conditions: Preventive Medicine
Interventions: DRUG: Anaferon for children|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Basilar Artery International Cooperation Study
Status: UNKNOWN
Conditions: Basilar Artery Thrombosis|Basilar Artery Embolism|Stroke of Basilar Artery|Stroke|Cerebrovascular Disorders|Basilar Artery Occlusion
Interventions: OTHER: Intra-arterial treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficiency of Pudendal Nerve Block Versus Penil Block for Circumsion in Children
Status: COMPLETED
Conditions: Postoperative Analgesia
Interventions: PROCEDURE: penil or pudendal nerve block in circumcision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evidence-based Evaluation of TCM Key Syndrome Differentiation and Treatment for Acute Ischemic Stroke
Status: UNKNOWN
Conditions: Ischemic Stroke
Interventions: DRUG: Integrative Treatment (EPACH Recipe Granules + NQABC Recipe Granules)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of a New Mathematical Formula to Predict Continuous Positive Air Pressure With an Oronasal Mask Interface.
Status: TERMINATED
Conditions: Obstructive Sleep Apnea (OSA)
Interventions: DEVICE: Full Face Mask with same CPAP Pressure|DEVICE: Full Face Mask with new Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial of Induction Chemotherapy and Chemoradiotherapy With TS-1 and Cisplatin (SP) as First-line Treatment in Patients With High Risk Advanced Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: TS-1 with Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Venlafaxine in Preventing Chronic Oxaliplatin-Induced Neuropathy In Patients Receiving Combination Chemotherapy
Status: COMPLETED
Conditions: Peripheral Neuropathy
Interventions: DRUG: venlafaxine|DRUG: placebo|OTHER: questionnaire administration|OTHER: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Antimony Plus Pentoxifylline in Cutaneous Leishmaniasis
Status: COMPLETED
Conditions: Cutaneous Leishmaniasis
Interventions: DRUG: Pentoxifylline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Surgical Debulking With Peritonectomy and Biweekly Intraperitoneal 5FU With Systemic Oxaliplatin/5FU/Leucovorin in Patients With Pseudomyxoma Peritonei or Peritoneal Carcinomatosis
Status: TERMINATED
Conditions: Peritoneal Neoplasms
Interventions: PROCEDURE: Surgical debulking with peritonectomy|DRUG: Intraperitoneal 5FU|DRUG: FOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Artificial Tears on the Parameters of the Eye and Its Impact on IOL Power Calculation for Cataract Surgery
Status: UNKNOWN
Conditions: Cataract Senile|Dry Eye
Interventions: DEVICE: sodium hyaluronate 0.1%|DEVICE: sodium hyaluronate 0.3%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Safety and Pharmacokinetics of Single and Multiple Doses of Prosetin in Healthy Volunteers
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: prosetin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Pharmacokinetics of VX-659 in Healthy Subjects and in Adults With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: VX-659|DRUG: Tezacaftor|DRUG: Ivacaftor|DRUG: VX-659 Matching Placebo|DRUG: Triple Combination (TC) Matching Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Safety and Performance of the enVista® One-Piece Hydrophobic Acrylic Trifocal Intraocular Lens in Subjects Undergoing Cataract Extraction
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: enVista MX60EFH trifocal intraocular lenses (IOLs)|DEVICE: enVista MX60E monofocal intraocular lenses (IOLs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Chardonnay Seed Flour on Vascular Health
Status: COMPLETED
Conditions: 1. Endothelial Dysfunction (EndoPAT Score <=2)
Interventions: DIETARY_SUPPLEMENT: Chardonnay Seed Flour (CSF)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Multifocal Contact Lens Designs With and Without an HEV Blocker on Visual Function
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: JJVC Investigational Multifocal Contact Lens TEST Lens|DEVICE: ACUVUE® OASYS Multifocal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of 5-FU + Leucovorin + CPT-11 in Patients With Resectable Liver Metastases From Colorectal Adenocarcinoma
Status: COMPLETED
Conditions: Colorectal Adenocarcinoma|Liver Metastases
Interventions: DRUG: perioperative chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy And Safety Of Heparin In Patients With Cardiovascular Surgery Using Cardiopulmonary Bypass
Status: UNKNOWN
Conditions: Prevention of Venous Thromboembolism
Interventions: BIOLOGICAL: Bovine Heparin|BIOLOGICAL: Porcine heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Almond Versus Pistachio on Weight Loss
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: BEHAVIORAL: Almond Group|BEHAVIORAL: Pistachio Group|BEHAVIORAL: Nut free group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RD13-01 for Patients With r/r CD7+ T-ALL/T-LBL
Status: UNKNOWN
Conditions: T Acute Lymphoblastic Leukemia|T-lymphoblastic Lymphoma
Interventions: DRUG: RD13-01 cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A-eyedrops on Ocular Alignment and Binocular Vision
Status: RECRUITING
Conditions: Exotropia|Exophoria|Myopia
Interventions: DRUG: 0.01% atropine eye drops|DRUG: placebo eye drops (0.1% sodium hyaluronate ophthalmic solution)|DRUG: 0.05% atropine eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Placebo Controlled Trial of Bosentan in Scleroderma Patients
Status: TERMINATED
Conditions: Systemic Scleroderma|Pulmonary Hypertension
Interventions: DRUG: Bosentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Standard Treatment +/- Apatinib in Extensive Stage Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Progression Free Survival
Interventions: DRUG: cisplatin, etoposide|DRUG: cisplatin, etoposide, apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Adherence to Statin Therapy Through a Medication Management Application
Status: RECRUITING
Conditions: Atherosclerosis
Interventions: OTHER: Medication management app (mediteo m+, Mediteo GmbH, Heidelberg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Desmopressin in the Treatment of Mixed Nocturia With Nocturnal Polyuria and Low Nocturnal Bladder Capacity
Status: COMPLETED
Conditions: Nocturia
Interventions: DRUG: Desmopressin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Natural Versus Synthetic Vitamin B Complexes in Human
Status: COMPLETED
Conditions: Healthy|Thiamine and Niacin Deficiency States|Pyridoxine Deficiency|Folic Acid Deficiency Anemia, Dietary|Vitamin B 12 Deficiency|Peroxidase; Defect|Polyphenols|Oxidative Stress|Homocystine; Metabolic Disorder
Interventions: DIETARY_SUPPLEMENT: Natural Panmol-B-Complex|DIETARY_SUPPLEMENT: Synthetic Vitamin B-Complex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fixed Dose Combination Drug (Polypill)for Secondary Cardiovascular Prevention.
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: FDC|DRUG: Separately drugs, simvastatin, aspirin and ramipril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SBRT + TACE for Primary Hepatocellular Carcinoma
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: Stereotactic Body Radiation Therapy (SBRT)|PROCEDURE: Transcatheter Arterial Chemoembolization (TACE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Based Smoking Cessation Among Cancer Survivors
Status: RECRUITING
Conditions: Tobacco Smoking
Interventions: DRUG: Nicoderm C-Q Transdermal Product|BEHAVIORAL: Orientation session|BEHAVIORAL: Craving-to-Quit app|BEHAVIORAL: Two brief follow-up phone calls|BEHAVIORAL: Group MT sessions|BEHAVIORAL: Brief advice on quitting smoking|BEHAVIORAL: Self-help smoking cessation materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Masticatory Muscles Electromyography in Post-pubertal Females With Forward Head Posture and Temporomandibular Disorders
Status: COMPLETED
Conditions: Head Pain|TMJ Disorder
Interventions: OTHER: Measurement of bilateral electromyographic activity of Masseter and Anterior Temporalis muscles.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency: A Natural History Study
Status: COMPLETED
Conditions: Severe Combined Immunodeficiency
Interventions: DRUG: ADA PBSC|DRUG: ADA Umbilical Cord Blood Cells|DRUG: Transduced Lymphocytes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Clinical Study of Pharmacokinetics, Tolerance and Safety of BCD-057 and Humira in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Adalimumab (BCD-057)|DRUG: Adalimumab (Humira)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Outcomes of Minimally Invasive Non- Surgical Versus Surgical Therapy in Furcation Involvement.
Status: RECRUITING
Conditions: Furcation Defects|Open Flap Debridement|Periodontal Diseases
Interventions: PROCEDURE: minimally invasive non- surgical therapy|PROCEDURE: open flap debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study in mCRC Patients RAS/BRAF wt Tissue and RAS Mutated LIquid BIopsy to Compare FOLFIRI Plus CetuxiMAb or BevacizumaB
Status: UNKNOWN
Conditions: Colorectal Cancer|Metastatic Colorectal Cancer|RAS Mutation
Interventions: DRUG: Bevacizumab|DRUG: Cetuximab|DRUG: 5-FU|DRUG: Irinotecan|DRUG: Calcium levofolinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UPNRIDE Powered Wheelchair for Individuals With Walking Impairment: Evaluation of Safety and Usability
Status: UNKNOWN
Conditions: Spinal Cord Injury Cervical
Interventions: DEVICE: UPnRIDE Powered Wheelchair
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Foot and Ankle Mobilisation in Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy|Limited Joint Mobility Syndrome|Ankle Joint Range of Motion|Forefoot Peak Plantar Pressure|Foot and Ankle Mobilisations|Home Exercise Programme / Stretches
Interventions: OTHER: Manual therapy / joint mobilisations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study of Talaporfin Sodium and Interstitial Light Emitting Diodes Treating Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular|Liver Neoplasms
Interventions: DRUG: Talaporfin sodium|DEVICE: Interstitial Light Emitting Diodes|PROCEDURE: Percutaneous placement of device in the liver|PROCEDURE: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Tolerability of Tirabrutinib (ONO/GS-4059) Given as Monotherapy in Participants With Relapsed/Refractory NHL and CLL
Status: COMPLETED
Conditions: Non Hodgkins Lymphoma|Chronic Lymphocytic Leukaemia
Interventions: DRUG: Tirabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Improve Quality of Care and Patient Health in the Field of Cardiovascular Risk Factors in General Practice
Status: COMPLETED
Conditions: High Risk Hypertensive Patients
Interventions: OTHER: Cardiovascular drugs strategies|BEHAVIORAL: Compliance|BEHAVIORAL: Exercise|BEHAVIORAL: Stop Smoking|BEHAVIORAL: Diet|OTHER: Feed Back
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Extracorporeal Shockwave Therapy on Ultrasonography Changes of Upper Trapezius Myofascial Trigger Points in Patients With Non Specific Neck Pain
Status: NOT_YET_RECRUITING
Conditions: Neck Pain
Interventions: OTHER: Extracorporeal Shockwave therapy|OTHER: Traditional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of Recombinant Trivalent Rotavirus Subunit Vaccine in Healthy Infants and Toddlers
Status: ACTIVE_NOT_RECRUITING
Conditions: Rotavirus Infections|Rotavirus Gastroenteritis
Interventions: BIOLOGICAL: Mid dose Recombinant Trivalent Subunit Rotavirus Vaccine|BIOLOGICAL: High dose Recombinant Trivalent Subunit Rotavirus Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Raltegravir Based Regimen on Platelet Reactivity, Platelet-monocyte Aggregation and Immune Activation
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Raltegravir|DRUG: Continuation of own regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nasal Gel Under Military Operational Conditions for the Prevention of Nausea Associated With Motion Sickness
Status: UNKNOWN
Conditions: Motion Sickness
Interventions: DRUG: scopolamine HBr|DRUG: Transdermal Scopolamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Immuno-therapy Study of Nivolumab Combined With Ipilimumab Compared to Nivolumab by Itself After Complete Surgical Removal of Stage IIIb/c/d or Stage IV Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: nivolumab|BIOLOGICAL: ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal vs Intravenous Chemotherapy Following Neoadjuvant Chemotherapy in Ovarian Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Metastatic Cancer|Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: DRUG: carboplatin|DRUG: cisplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Hylo-Dual Versus Patanol in Children With Seasonal Allergic Conjunctivitis
Status: RECRUITING
Conditions: Conjunctivitis, Allergic|Conjunctivitis, Vernal
Interventions: DRUG: Hyaluronic acid 0.05% & Ectoine 2.0%|DRUG: Olopatadine hydrochloride ophthalmic solution 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Prospective Cohort Study of Twin Maternal-Child Dyads in China
Status: RECRUITING
Conditions: Twin Pregnancy, Antepartum Condition or Complication|Twin to Twin Transfusion as Antepartum Condition|Pre-Term|Pre-Eclampsia|Twin Monochorionic Diamniotic Placenta|Twin Dichorionic Diamniotic Placenta|High Risk Pregnancy|Twin Placenta
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phaco-Trabeculotomy Vs Phaco-Trabeculectomy
Status: COMPLETED
Conditions: Ophthalmopathy|Glaucoma|Glaucoma, Angle-Closure
Interventions: PROCEDURE: Phacoemulsification combined with trabeculectomy|PROCEDURE: Phacoemulsificaiton combined with ab-externo trabeculotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Botulinum Toxin-A Injection and Shock Waves on Hypertrophic Scars in Hand-burned Children
Status: RECRUITING
Conditions: Hand-burned Children
Interventions: OTHER: physical therapy treatment|OTHER: Botulinum toxin-A injection in addition to physical therapy program|OTHER: shock wave therapy in addition to physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Neuro-Music-Therapy for Patients With Chronic Tinnitus - a Controlled Clinical Trial
Status: COMPLETED
Conditions: Tinnitus
Interventions: BEHAVIORAL: Neuro-Music-Therapy according to the Heidelberg Model|BEHAVIORAL: Counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Schizophrenic Smokers: Effects on Craving, Cues and Withdrawal
Status: WITHDRAWN
Conditions: Tobacco Use Disorder
Interventions: DRUG: varenicline|BEHAVIORAL: Adaptation of Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Eradication of Nasal Carriage of Staphylococcus Aureus (SA) With Mupirocin (Bactroban 2% Nasal Ointment)
Status: COMPLETED
Conditions: Staphylococcal Infection
Interventions: DRUG: Mupirocin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extended Versus Limited Thoracoscopic Sympathectomy: Its Impact on Palmar and Plantar Hyperhidrosis
Status: COMPLETED
Conditions: Hyperhidrosis Due to Autonomic Dysregulation (Disorder)
Interventions: PROCEDURE: thoracoscopic sympathectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Thoughts in Fibromyalgia: Impact of Rumination on the Emotional and Cognitive Dimensions of Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: Evaluate the link between an abstract / analytical thinking style and depressive manifestations in FM.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study on Efficacy and Safety of Reparixin in the Treatment of Hospitalized Patients With Severe COVID-19 Pneumonia.
Status: COMPLETED
Conditions: Pneumonia, Viral
Interventions: DRUG: Reparixin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rotigotine Versus Placebo, A Study To Evaluate The Efficacy In Advanced Stage Idiopathic Parkinson's Disease Patients
Status: COMPLETED
Conditions: Idiopathic Parkinson's Disease
Interventions: DRUG: Rotigotine|DRUG: Placebo Patch|DRUG: L-dopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Coenzyme A Combined With Abiraterone on Patients With CRPC
Status: UNKNOWN
Conditions: Castration-resistant Prostate Cancer
Interventions: DRUG: Coenzyme A Combined With Abiraterone|DRUG: Abiraterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of DFP-10917 in Patients With Acute Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Lymphocytic Leukemia
Interventions: DRUG: DFP-10917
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Trial of Vaccine Therapy of HIV-1 Infected Individuals With 50-500 CD4 Cells/mm3
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: rgp120/HIV-1MN|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: Hyperbaric Levobupivacaine for Spinal Anaesthesia
Status: COMPLETED
Conditions: This Study Was Focused on Selective Spinal Anesthesia for Lower Extremity Surgery in Order to Achieve Early Mobilization and to Shorten Hospital Stay
Interventions: DRUG: levobupivacaine|DRUG: levobupivacaine|DRUG: levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pregnancy-related Changes in Melanocytic Nevi
Status: COMPLETED
Conditions: Melanocytic Nevi (MN)
Interventions: OTHER: standard-of-care clinical skin examination|DIAGNOSTIC_TEST: skin assessment with the 2D FotoFinder ATBM master system|OTHER: data collection by participant questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Healing of Diabetic Foot Ulcers With Compounded Anti-Infective Irrigation Therapy
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: vancomycin-tobramycin-itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibuprofen IV vs Acetaminophen IV for the Treatment of Pain Following Orthopaedic Low Extremity Surgery
Status: COMPLETED
Conditions: Lower Extremity Problem|Surgery|Postoperative Pain
Interventions: DRUG: Ibuprofen|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: EXPRESS: Examining Pagoclone for Persistent Developmental Stuttering Study
Status: COMPLETED
Conditions: Persistent Developmental Stuttering
Interventions: DRUG: Pagoclone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Could Early Atorvastatin Offer Anti Inflammatory Effects Upon Brain in Traumatic Head Injury?
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Atorvastatin|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lisdexamphetamine vs Methylphenidate for Pediatric Patients With ADHD and Type 1 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Attention Deficit Disorder With Hyperactivity|Diabetes Mellitus, Type 1
Interventions: BEHAVIORAL: parental training in behavior management|DRUG: Lisdexamfetamine|DRUG: Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy and Sargramostim After Rituximab in Treating Patients With Refractory or Progressive Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: autologous immunoglobulin idiotype-KLH conjugate vaccine|BIOLOGICAL: sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topotecan, Paclitaxel, and Filgrastim in Treating Patients With Previously Untreated Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: paclitaxel|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manual vs Amigo SmartTouch Atrial Fibrillation Study
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Catheter ablation for atrial fibrillation, manual|DEVICE: Ablation using Amigo remote catheter system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monitoring Early Response to Targeted Therapy in Stage IV HER2+ Breast Cancer Patients With Advanced PET/MR Imaging
Status: RECRUITING
Conditions: HER2-positive Breast Cancer
Interventions: DRUG: [18F]-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Noninvasive Real-time Intracardiac Pressure Measurements Using Subharmonic Ultrasound
Status: COMPLETED
Conditions: Cardiac Catheterization|Blood Pressure|Heart Ventricles|Echocardiography|Heart Failure
Interventions: DRUG: Sonazoid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Reactogenicity and Immunogenicity of Vi-DT;Typhoid Conjugate Vaccine
Status: COMPLETED
Conditions: Typhoid
Interventions: BIOLOGICAL: Vi-DT|BIOLOGICAL: FluQuadri™|OTHER: 0.9% sodium chloride isotonic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Role of Apoptosis Associated Markers in Pathogenesis of Pulmonary Tuberculosis
Status: UNKNOWN
Conditions: To Compare the Serum Apoptosis-associated Markers Between Patients With Active TB and Patients With LTBI|To Evaluate the Efficiency of Apoptosis-associated Markers to Differentiate Potential of Active TB From LTBI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Robot-LVA Study: Robot-assisted Microsurgical Lymphaticovenous Anastomosis in Breast Cancer-related Lymphedema
Status: RECRUITING
Conditions: Lymphedema|Lymphedema Arm|Lymphedema of Upper Arm|Lymphedema of Upper Limb|Lymphedema; Surgical|Lymphedema, Secondary|Lymphedema of Limb|Lymphedema, Breast Cancer|Lymphedema, Non-Filarial
Interventions: DEVICE: Lymphaticovenous anastomosis using Microsure Motion Stabilizer|PROCEDURE: Lymphaticovenous anastomosis (manual)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study Comparing ABT-143 to Simvastatin in Subjects With Elevated Levels of Low Density Lipoprotein Cholesterol ("Bad Cholesterol") and Triglycerides
Status: COMPLETED
Conditions: Dyslipidemia, Hypercholesterolemia, Hypertriglyceridemia
Interventions: DRUG: ABT-143|DRUG: simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: STOPPER CHINA:With Tandem Microspheres in the Treatment of Localized Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Localized Hepatocellular Carcinoma
Interventions: DEVICE: Tandem Microsphere loaded with Epirubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patients Completing Core Protocol (CAMN107A2103), Exhibiting Stable Disease (SD), Partial Response (PR) or Complete Response (CR) to Nilotinib in Combination With Imatinib
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Nilotinib, Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Urinary Tract Injuries During Caesarean Section for Morbidly Adherent Placenta: Prospective and Retrospective Study
Status: UNKNOWN
Conditions: Urinary Tract Injuries During Caesarean Section for Morbidly Adherent Placenta: Prospective and Retrospective Study
Interventions: OTHER: ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Five Intraarticular Strategies on Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: PROCEDURE: Non arthroscopic joint lavage|PROCEDURE: Non arthroscopic joint lavage plus corticosteroid|PROCEDURE: Non arthroscopic joint lavage plus hyaluronic acid|PROCEDURE: Intraarticular injection of corticosteroid|PROCEDURE: Intraarticular injection of hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI Guided Radiotherapy and Radiobiological Data: the ISRAR Database (Irm Sequences for Radiobiological Adaptative Radiotherapy)
Status: RECRUITING
Conditions: Prostate Cancer|Glioblastoma|Head and Neck Cancer|Kidney Cancer|Cervix Cancer
Interventions: OTHER: 3 MRI sequences (T2*, IVIM and Multi Echo-Gradient), without injection, are performed
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Novel Therapies for Resistant FSGS (FONTII): Phase II Clinical Trial
Status: COMPLETED
Conditions: Focal Segmental Glomerulosclerosis
Interventions: DRUG: Adalimumab|DRUG: Lisinopril, losartan, and atorvastatin|DRUG: galactose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrical Impedance Tomography: Collapse in Dependent Areas as a Predictor of Response to Prone Position Ventilation in COVID-19 Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: SARS-CoV Infection|Acute Respiratory Distress Syndrome
Interventions: DEVICE: Electrical Impedance tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TT-816 as Monotherapy or in Combination With a PD-1 Inhibitor in Patients With Advanced Cancers (SEABEAM) (MK3475-E88)
Status: TERMINATED
Conditions: Advanced Cancer|Advanced Solid Tumor|Cancer|Oncology
Interventions: DRUG: TT-816|DRUG: A PD-1 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT