pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Neuroprotection in Patients Undergoing Aortic Valve Replacement
Status: COMPLETED
Conditions: Aortic Stenosis|Brain Infarction|Cerebrovascular Accident|Stroke
Interventions: DEVICE: Embol-X Embolic Protection Device|DEVICE: CardioGard Cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Electroacupuncture Analgesia for EUS: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Patients Undergoing Endoscopic Ultrasound
Interventions: PROCEDURE: Electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Promoting Respect and Ongoing Safety Through Patient-centeredness, Engagement, Communication and Technology
Status: COMPLETED
Conditions: Medical Intensive Care Unit (MICU) Patients|Oncology Unit Patients
Interventions: OTHER: Web-Based Patient Centered Toolkit (PCTK)|BEHAVIORAL: The Patient-SatisfActive® Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ketoconazole and Dexamethasone in Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Ketoconazole|DRUG: Hydrocortisone|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Withdrawal Exposure and Negative Affect Withdrawal (NAW) Regulation Training for Smoking Cessation
Status: RECRUITING
Conditions: Tobacco Dependence
Interventions: BEHAVIORAL: cognitive-behavioral withdrawal regulation strategies|BEHAVIORAL: relaxation strategies|BEHAVIORAL: early withdrawal exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lucentis for Age-related Macular Degeneration Pigment Epithelial Detachments
Status: COMPLETED
Conditions: Age-related Macular Degeneration|Pigment Epithelial Detachment|Neovascular Macular Degeneration|Wet Macular Degeneration
Interventions: DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Project Connect Online: An Internet-based Intervention for Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: BEHAVIORAL: Project Connect Online|BEHAVIORAL: PCO PLUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pilot Study of 566C80 for the Salvage Treatment of Toxoplasmic Encephalitis in Patients Infected With the Human Immunodeficiency Virus (HIV) Who Have Failed or Are Intolerant of Pyrimethamine-Sulfadiazine
Status: COMPLETED
Conditions: Toxoplasmosis, Cerebral|HIV Infections
Interventions: DRUG: Atovaquone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Tenelia Triple Combination Study
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Teneligliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Pembrolizumab (MK-3475) Coformulated With Hyaluronidase (MK-3475A) in Participants With Relapsed or Refractory Classical Hodgkin Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL)(MK-3475A-F65)
Status: RECRUITING
Conditions: Classical Hodgkin Lymphoma Recurrent|Classical Hodgkin Lymphoma Refractory|Primary Mediastinal Large B-cell Lymphoma Recurrent|Primary Mediastinal Large B-cell Lymphoma Refractory
Interventions: BIOLOGICAL: Pembrolizumab Coformulated With Hyaluronidase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Hyperoxia and Hypergravity on Lung Ventilation and Perfusion
Status: COMPLETED
Conditions: Atelectasis
Interventions: OTHER: hypergravity|OTHER: gas mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Ivabradine Versus Propranolol Premedication During Hypotensive Anesthesia in Endoscopic Sinus Surgery
Status: UNKNOWN
Conditions: Ivabradine|Propranolol|Hypotensive Anesthesia
Interventions: DRUG: Ivabradine|DRUG: Propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Among the Effects of Blood Flow Restriction Training and Conventional Exercise in Knee Osteoarthritis.
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Hypertrophy
Interventions: OTHER: Blood flow Restriction/Resistance Training|OTHER: Conventional Therapy Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MV-NIS Infected Mesenchymal Stem Cells in Treating Recurrent Ovarian, Primary Peritoneal or Fallopian Tube Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Fallopian Tube Clear Cell Adenocarcinoma|Fallopian Tube Endometrioid Adenocarcinoma|Fallopian Tube Mucinous Adenocarcinoma|Fallopian Tube Serous Adenocarcinoma|Fallopian Tube Transitional Cell Carcinoma|Fallopian Tube Undifferentiated Carcinoma|Malignant Ovarian Brenner Tumor|Ovarian Clear Cell Adenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mucinous Adenocarcinoma|Ovarian Seromucinous Carcinoma|Ovarian Serous Adenocarcinoma|Ovarian Transitional Cell Carcinoma|Ovarian Undifferentiated Carcinoma|Primary Peritoneal Serous Adenocarcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|PROCEDURE: Mesenchymal Stem Cell Transplantation|BIOLOGICAL: Oncolytic Measles Virus Encoding Thyroidal Sodium Iodide Symporter|PROCEDURE: Echocardiography|PROCEDURE: Multigated Acquisition Scan|PROCEDURE: Biospecimen Collection|PROCEDURE: Chest Radiography|PROCEDURE: Single Photon Tomography and Computed Tomography Scan|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicentre randomiSed Controlled TRial of IntraVEnous Immunoglobulin Versus Standard Therapy for Transverse Myelitis
Status: TERMINATED
Conditions: Myelitis, Transverse|Neuromyelitis Optica
Interventions: DRUG: Intravenous Methylprednisolone|DRUG: Intravenous Immunoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GEN3014 Safety Trial in Relapsed or Refractory Hematologic Malignancies
Status: RECRUITING
Conditions: Relapsed or Refractory Multiple Myeloma (RRMM)|Diffuse Large B Cell Lymphoma (DLBCL)|Acute Myeloid Leukemia (AML)
Interventions: BIOLOGICAL: GEN3014|DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Getting Children Between 3-6 To Watch Small Aquarium Fish On Physiological Parameters, Pain and Stress During Blood Collection
Status: UNKNOWN
Conditions: Bloodletting
Interventions: OTHER: animal assisted therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Trial of Docetaxel in Combination With Gemcitabine in Platinum-Resistant Ovarian Cancer and Primary Peritoneal Carcinoma
Status: COMPLETED
Conditions: Ovarian Carcinoma|Peritoneal Neoplasms
Interventions: DRUG: Docetaxel and Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Different Imaging Techniques in Patients With Different Types of Interstitial Lung Disease
Status: RECRUITING
Conditions: Lung Diseases, Interstitial
Interventions: DIAGNOSTIC_TEST: Spirometry|DIAGNOSTIC_TEST: Diffusing Capacity of the Lung for Carbon Monoxide (DLCO)|DIAGNOSTIC_TEST: Magnetic Resonance Imaging|DIAGNOSTIC_TEST: Chest Computer Tomography|DIAGNOSTIC_TEST: Blood biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Statin Monotherapy for Treatment of Endocrine Metabolic Disease Risk
Status: UNKNOWN
Conditions: Spinal Cord Injuries|Osteoporosis|Metabolic Syndrome
Interventions: DRUG: Rosuvastatin Calcium|DRUG: Placebo Oral Tablet|DIETARY_SUPPLEMENT: Coenzyme Q10|DIETARY_SUPPLEMENT: Calcium Carbonate|DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Care Pathway for Patients Undergoing VATS Lobectomy or Segmentectomy
Status: UNKNOWN
Conditions: VATS Lobectomy|VATS Segmentectomy|Care Pathway|Lung Nodule
Interventions: OTHER: Post-operative care pathway for patients undergoing VATS lobectomy or segmentectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Suprascapular Nerve Block With Oral Gabapentin For Pain Management In Frozen Shoulder
Status: COMPLETED
Conditions: Pain, Shoulder
Interventions: PROCEDURE: Ultrasound Guided Continuous Suprascapular Nerve Block With methyl prednisolone and marcaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of IV vs Oral Dexamethasone on Postoperative Nausea, Vomiting, and Pain
Status: COMPLETED
Conditions: Nausea and Vomiting, Postoperative
Interventions: DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Guided Imagery Lifestyle Intervention to Promote Health and Prevent Diabetes in Youth
Status: COMPLETED
Conditions: Obesity|Insulin Resistance|Stress
Interventions: BEHAVIORAL: Lifestyle Education (LS)|BEHAVIORAL: LS + Stress Reduction Guided Imagery|BEHAVIORAL: LS + Activity/Eating Guided Imagery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Administration of Anti-CD19-chimeric-antigen-receptor-transduced T Cells From the Original Transplant Donor to Patients With Recurrent or Persistent B-cell Malignancies After Allogeneic Stem Cell Transplantation
Status: COMPLETED
Conditions: Leukemia, B-cell|Lymphoma, Hodgkins|Lymphoma, Non-hodgkins|Lymphoma, B-Cell
Interventions: PROCEDURE: Allogeneic stem cell transplant|BIOLOGICAL: Anti-CD19-chimeric-antigen-receptor-transduced T cells|PROCEDURE: Leukapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benjakul Extract and Loratadine for Treatment Allergic Rhinitis Patients
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Benjakul Extract|DRUG: Loratadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Effect of Olmesartan Medoxomil, Losartan Potassium, and Atenolol on the Ability of Overweight Patients With High Blood Pressure to Respond to Insulin
Status: COMPLETED
Conditions: Hypertension|Insulin Resistance|Metabolic Syndrome
Interventions: DRUG: Olmesartan medoxomil|DRUG: Losartan potassium|DRUG: Atenolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy of Toripalimab Combined With Chemotherapy After HIFU Induction in the Treatment of Early Triple-negative Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|TNBC - Triple-Negative Breast Cancer
Interventions: DRUG: Toripalimab|DRUG: Epirubicin|PROCEDURE: High Intensity Focused Ultrasoun|DRUG: Cyclophosphamide|DRUG: Carboplatin|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of AK102 in Patients With Hyperlipidemia
Status: UNKNOWN
Conditions: Hyperlipidemia
Interventions: BIOLOGICAL: AK102|BIOLOGICAL: AK102|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Combination Ambrisentan Plus Spironolactone in Pulmonary Arterial Hypertension Study
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Ambrisentan plus Spironolactone|DRUG: Ambrisentan plus Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of GT267-004 Versus Vancomycin and GT267-004 Versus Metronidazole in Patients With C. Difficile-Associated Diarrhea
Status: COMPLETED
Conditions: Clostridium Enterocolitis|Diarrhea
Interventions: DRUG: Tolevamer potassium-sodium (GT267-004)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Significance of Release of T-follicular Helper and T-follicular Regulatory Cells in Autoimmune Haemolytic Anemia Before and After Tratment
Status: NOT_YET_RECRUITING
Conditions: Autoimmune Hemolytic Anemia
Interventions: DIAGNOSTIC_TEST: flowcytometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: VEGFA-targeting Gene Therapy to Treat Retinal and Choroidal Neovascularization Diseases
Status: UNKNOWN
Conditions: Neovascular Age-related Macular Degeneration|Diabetic Macular Edema|Retinal Vein Occlusion
Interventions: GENETIC: BD311
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Colchicine Cardiovascular Outcomes Trial (COLCOT)
Status: COMPLETED
Conditions: Coronary Artery Disease|Myocardial Infarction
Interventions: DRUG: colchicine|DRUG: colchicine placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Blue Enriched Versus Standard Light Treatment for Seasonal Affective Disorder(SAD)
Status: COMPLETED
Conditions: Seasonal Affective Disorder
Interventions: DEVICE: Original Energy Light,|DEVICE: Original Energy Light prototype|DEVICE: Original Energy Light prototype
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib Treatment in Waiting List of Liver Transplantation After TACE Failure in Patients With Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma Non-resectable
Interventions: DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Active Health Education to Increase HPV Vaccine Coverage in Youth: A Stepped-wedge, Cluster, and Randomized Trial
Status: NOT_YET_RECRUITING
Conditions: Vaccine Refusal|Vaccine Hesitancy
Interventions: BEHAVIORAL: Active Students Education plus Teacher Training|BEHAVIORAL: Active Students Education|BEHAVIORAL: Basic Health Unit Active Orientation|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: NHFOV vs. NCPAP as a Primary Treatment to Neonatal Respiratory Distress Syndrome(NRDS)
Status: COMPLETED
Conditions: Preterm Infants
Interventions: PROCEDURE: noninvasive high-frequency ventilation (nHFOV)|PROCEDURE: nasal continuous positive airway pressure (nCPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Investigate The Effects Of End Stage Renal Disease And Hemodialysis On The Pharmacokinetics Of Ropinirole
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: ropinirole dosing for up to 28 days
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Radiation Therapy in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Liver Cancer
Interventions: RADIATION: 3-dimensional conformal radiation therapy|RADIATION: intensity-modulated radiation therapy|RADIATION: stereotactic body radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of Lidocaine-Containing Hyaluronic Acid Filler in the Treatment of Nasolabial Folds.
Status: COMPLETED
Conditions: Wrinkles Such as Nasolabial Folds
Interventions: DEVICE: PavéDerm J-Fill Soft Dermal Filler|DEVICE: Restylane® Lyft Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Cabazitaxel Plus Lapatinib as Therapy for HER2-Positive Metastatic Breast Cancer Patients With Intracranial Metastases
Status: TERMINATED
Conditions: Metastatic Breast Cancer With Intracranial Metastases
Interventions: DRUG: cabazitaxel|DRUG: lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Drugs, Cidofovir and Ganciclovir, in Treating Patients With AIDS Who Have CMV Retinitis
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Cidofovir|DRUG: Probenecid|DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Correlation Between Optical Coherence Tomography Angiography and Photopic Negative Response in Patients With Glaucoma
Status: COMPLETED
Conditions: Open Angle Glaucoma
Interventions: DIAGNOSTIC_TEST: Optical Coherence Tomography- Angiography|DIAGNOSTIC_TEST: Photopic negative response
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diagnostic Accuracy of Human Transcriptional Activator(MYB) Expression by ELISA Technique Versus Immmunohistochemistry in Detecting Salivary Gland Carcinomas
Status: UNKNOWN
Conditions: Malignant Neoplasm of Salivary Gland|Benign Neoplasm of Salivary Gland
Interventions: DEVICE: enzyme linked immunosorbent assay (ELISA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Connective Tissue Grafting for Single Tooth Recession & the Impact of the Thickness of the Palatal Harvest Tissue
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: connective tissue graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Retarded Surgery Following Neoadjuvant Chemotherapy in Advanced Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer Stage IV|Ovarian Cancer Stage IIIC|Ovarian Cancer Stage IIIb
Interventions: PROCEDURE: Retarded IDS (Interval Debulking Surgery)|PROCEDURE: Standard IDS (Interval Debulking Surgery)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3475766 in Healthy Participants
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DRUG: LY3475766 - IV|DRUG: LY3475766 - SC|DRUG: Placebo - IV|DRUG: Placebo - SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of VitaBeard® on Facial Hair Growth in Healthy Adult Men
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Multivitamin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Phase 3b Study of Erythropoietin Drugs Using a Specified Dosing Algorithm in Patients With Chronic Kidney Disease on Hemodialysis
Status: COMPLETED
Conditions: Chronic Kidney Disease (CKD)
Interventions: BIOLOGICAL: Epoetin Hospira Arm|OTHER: Standard of Care Arm|DRUG: IV Iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pyrotinib Combined With Trastuzumab, Dalpiciclib, Letrozole Versus TCbHP (Trastuzumab Plus Pertuzumab With Docetaxel and Carboplatin) as Neoadjuvant Treatment in HR +/HER2 + Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Pyrotinib|DRUG: Trastuzumab|DRUG: Dalpiciclib|DRUG: Letrozole|DRUG: Pertuzumab|DRUG: Docetaxel|DRUG: Carboplatin|DRUG: Gonadotropin-releasing hormone agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of NMES and HPRO on Recovery After SAH- Pilot Study
Status: RECRUITING
Conditions: Subarachnoid Hemorrhage|Muscle Atrophy|Inflammation|Nutritional and Metabolic Disease
Interventions: DEVICE: Neuromuscular Electrical Stimulation (NMES)|DIETARY_SUPPLEMENT: High Protein Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study on Neoadjuvant Therapy of AK104 Combined With Nab-paclitaxel/Carboplatin in Fertility Preserving Surgery
Status: RECRUITING
Conditions: Neoadjuvant Immunotherapy|Cervical Cancer|Fertility-sparing Surgery
Interventions: DRUG: AK104|DRUG: Carboplatin|DRUG: Nab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Neuromodulation for Treatment of Symptoms Due to Mild or Moderate Traumatic Brain Injury
Status: COMPLETED
Conditions: Brain Injuries, Traumatic
Interventions: DEVICE: Balance and Gait Training using neurostimulation modulation.|DEVICE: Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Whether BI 1839100 Improves Cough in People With Idiopathic Pulmonary Fibrosis or Progressive Pulmonary Fibrosis
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis|Progressive Pulmonary Fibrosis
Interventions: DRUG: BI 1839100|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vitamin C on Growth Hormone Secretion
Status: WITHDRAWN
Conditions: Obese|Disorder of Vitamin C|Growth Hormone Secretion Abnormality
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Vitamin C 250 mg once daily|DIETARY_SUPPLEMENT: Vitamin C 1,000 mg once daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sacral Nerve Stimulation in Treating Low Anterior Resection Syndrome or Fecal Incontinence in Patients With Locally Advanced Rectal Cancer or Other Pelvic Cancer, the RESTORE Study
Status: TERMINATED
Conditions: Low Anterior Resection Syndrome|Malignant Anal Neoplasm|Malignant Bladder Neoplasm|Malignant Cervical Neoplasm|Malignant Ovarian Neoplasm|Malignant Pelvic Neoplasm|Malignant Prostate Neoplasm|Malignant Uterine Neoplasm|Malignant Vaginal Neoplasm|Malignant Vulvar Neoplasm|Rectal Carcinoma
Interventions: PROCEDURE: Explantation|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DEVICE: Sacral Nerve Stimulator|DEVICE: Sacral Nerve Stimulator Battery|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reducing Breast Cancer-related Fatigue and Improving Cognition With Non-Invasive Brain Stimulation
Status: TERMINATED
Conditions: Breast Cancer|Cognitive Dysfunction|Fatigue
Interventions: DEVICE: tDCS|OTHER: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of ERAS Therapeutic Protocol for Complicated Appendicitis in Children
Status: UNKNOWN
Conditions: Enhanced Recovery After Surgery|Appendicitis|Children, Only
Interventions: OTHER: Enhanced Recovery After Surgery therapeutic protocol|OTHER: Conventional management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efavirenz and Lamivudine/Zidovudine for Treatment-Naive HIV Infected People in Wenxi County, Shanxi Province, China
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Efavirenz|DRUG: Lamivudine/zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Extinction Learning in Post Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Chronic Posttraumatic Stress Disorder
Interventions: DRUG: Psychotherapy plus Methylene Blue, USP|BEHAVIORAL: Psychotherapy plus Placebo|BEHAVIORAL: Delayed Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Uptake of an Omega-3 Oil in Healthy Adults
Status: COMPLETED
Conditions: Absorption|Pharmacokinetics
Interventions: DIETARY_SUPPLEMENT: PL+ omega 3 fatty acids|DIETARY_SUPPLEMENT: FO EE fatty acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Atorvastatin Use and Portal Hypertension in Patients With Hepatitis B Virus-related Liver Cirrhosis: A Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Hepatitis B|Portal Hypertension
Interventions: DRUG: Atorvastatin 10mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glue Embolization vs Conservative Treatment for Pelvic Congestion Syndrome
Status: RECRUITING
Conditions: Glue Embolization|Pelvic Congestion Syndrome
Interventions: DRUG: Micronized purified flavonoid fraction (Daflon ®)|OTHER: Glue embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Video Laryngoscopy With Rigid Stylet vs Video Laryngoscopy With the TCI Articulating Introducer for Endotracheal Intubation in Simulated Difficult Airways
Status: NOT_YET_RECRUITING
Conditions: Intubation; Difficult or Failed
Interventions: DEVICE: TCI Articulating Introducer|DEVICE: GlideRite® Rigid Stylet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Milk Biofortification Promotes Health Benefits in Institutionalized Elderly
Status: COMPLETED
Conditions: Nutrient Deficiency|Age-Related Immunodeficiency|Vitamin E Deficiency|Selenium Deficiency|Fatty Acid Deficiency|Institutionalization; Disinhibited Attachment
Interventions: DIETARY_SUPPLEMENT: Milk Antioxidant group(A)|DIETARY_SUPPLEMENT: Milk Oil group(O)|DIETARY_SUPPLEMENT: Milk Antioxidant and oil(AO)|DIETARY_SUPPLEMENT: Milk Control group(C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Interest of Dosage of Anti-PB230, Anti-PB180 and Cytokines for Monitoring of Patients Suffering From Bullous Pemphigoid
Status: COMPLETED
Conditions: Bullous Pemphigoid
Interventions: OTHER: Blood sample for dosages of cytokines (IL-17 and IL-23) and of the protease MMP-9
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Postoperative Analgesic Effect of Nefopam
Status: COMPLETED
Conditions: Stomach Neoplasms
Interventions: DRUG: Nefopam|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Combination Therapy With Ipilimumab and HighDose IFN-α2b for Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: administration of ipilimumab10mg/kg|DRUG: administration of ipilimumab 3mg/kg + HDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Weekly GLP1 Agonist Treatment in "Double Diabetes"
Status: ACTIVE_NOT_RECRUITING
Conditions: Double Diabetes
Interventions: DRUG: Insulin + semaglutide treatment|DRUG: Usual insulin treatment|BIOLOGICAL: Biological check-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addition of Chidamide to the Combination Treatment of Decitabine Plus Camrelizumab in Combination Treatment Resistant/Relapsed Patients With Classical Hodgkin Lymphoma
Status: RECRUITING
Conditions: Hodgkin Lymphoma
Interventions: DRUG: Chidamide|DRUG: Camrelizumab|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Infliximab in Eyes With Penetrating Keratoplasty
Status: RECRUITING
Conditions: Glaucoma Following Surgery
Interventions: DRUG: Topical infliximab|OTHER: No topical infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigation to Understand and Optimize Psilocybin
Status: NOT_YET_RECRUITING
Conditions: Depression
Interventions: DRUG: Psilocybin|DEVICE: Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)|DEVICE: Sham taVNS|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Efficacy and Safety of Albiglutide as Compared With Liraglutide.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BIOLOGICAL: albiglutide|DRUG: liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep Apnea Video Education for CPAP (SAVE-CPAP)
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: OTHER: Enhanced education|OTHER: Usual education|OTHER: Usual follow up|OTHER: Enhanced follow up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy
Status: ENROLLING_BY_INVITATION
Conditions: Hypercholesterolemia|Carotid Intimal Medial Thickness 1|Seizure|Epilepsy|Cardiovascular Disease|Cerebrovascular Disease|Heart Disease|Coronary Disease
Interventions: DIETARY_SUPPLEMENT: Modified Atkins or Ketogenic Diet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Crizotinib and Ganetespib (STA-9090) in ALK Positive Lung Cancers
Status: COMPLETED
Conditions: Advanced Lung Cancer
Interventions: DRUG: Ganetespib (STA-9090) and crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: What Factors Affect Breast Cancer Neoadjuvant Chemotherapy Efficacy?
Status: UNKNOWN
Conditions: Breast Neoplasm Malignant Breast Tissue
Interventions: OTHER: Magnetic Resonance Imaging|OTHER: Histopathological Analysis|OTHER: Health Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of DAV132 in Patients at High-Risk for Clostridium Difficile Infection (CDI)
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: DEVICE: DAV132
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Perioperative DEXamethasone on Postoperative Complications After PANcreaticoduodenectomy
Status: COMPLETED
Conditions: Pancreaticoduodenectomy
Interventions: DRUG: Dexamethasone|DRUG: Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hemodynamics During Induction of General Anesthesia After Prophylactic Ephedrine, Phenylephrine or Norepinephrine.
Status: RECRUITING
Conditions: Hemodynamic Instability|Anesthesia, General|Anesthesia, Intravenous
Interventions: DRUG: Ephedrine|DRUG: Phenylephrine|DRUG: Norepinephrine|DRUG: Sodium chloride|DRUG: Propofol|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Research on Building and Application of Internet-based Home Pre-rehabilitation Model for Lung Surgery Patients.
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer
Interventions: BEHAVIORAL: Prerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: WHO Labor Care Guide for Obstetric Care Providers in Public Health Facilities in Mbarara, Southwestern Uganda
Status: NOT_YET_RECRUITING
Conditions: Intrapartum Fetal Monitoring
Interventions: BEHAVIORAL: Labor Care Guide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Compare rhuFab V2 With Verteporfin Photodynamic in Treating Subfoveal Neovascular Macular Degeneration
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: rhuFab V2 (ranibizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Trunk Support on Academic Engagement of Children With Severe Disability
Status: COMPLETED
Conditions: Cerebral Palsy|Traumatic Brain Injury|Metabolic Disease|Hypotonia
Interventions: DEVICE: customized posture support
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerance of Hypertonic Sodium Chloride (NaCl 5%) Eye Drops Without Preservatives in Corneal Edema
Status: UNKNOWN
Conditions: Corneal Edema
Interventions: DEVICE: hypertonic Sodium chloride (NaCl 5%) eye drops solution in single-dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of TAK-653 in Treatment-Resistant Depression
Status: WITHDRAWN
Conditions: Treatment-Resistant Depression
Interventions: DRUG: TAK-653|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dihydropyridine Calcium Channel Inhibitors on Respiratory Gas Exchanges in the Intensive Care Unit: a Pharmacovigilance Study in VigiBase® and a Comparison With Urapidil
Status: COMPLETED
Conditions: Hypoxia
Interventions: DRUG: dihydropyridine calcium channel inhibitors use
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Heating Pad for in Office Cystoscopy and Urodynamic Testing
Status: RECRUITING
Conditions: Anxiety|Pain|Distress, Emotional
Interventions: DEVICE: Electrical heating pad|DEVICE: Sham heating pad
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Usefulness of the Probiotic 'Lactobacillus Reuteri' in the Therapy of Quadruple Eradication of Helicobacter Pylori Infection in Usual Clinical Practice.
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DIETARY_SUPPLEMENT: GASTRUS|OTHER: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Scavenging of Reactive Carbonyl Species by Dietary Flavonoids in Humans
Status: COMPLETED
Conditions: Human Health|Reactive Carbonyl Species|Polyphenols
Interventions: DIETARY_SUPPLEMENT: Soymilk, green tea, or blueberry|DIETARY_SUPPLEMENT: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Efficacy and Safety of BAT5906 Injection
Status: COMPLETED
Conditions: Wet Age-related Macular Degeneration
Interventions: DRUG: 2.5mg of BAT5906|DRUG: 4mg of BAT5906
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contribution of Angiotensin II to Supine Hypertension in Autonomic Failure
Status: TERMINATED
Conditions: Hypertension|Pure Autonomic Failure|Multiple System Atrophy
Interventions: DRUG: Losartan|DRUG: Captopril|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: tDCS and Cognition in Adults With Multiple Sclerosis or Encephalitis
Status: COMPLETED
Conditions: Multiple Sclerosis|Encephalitis
Interventions: DEVICE: Sham Transcranial direct current stimulation|DEVICE: Anodal Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexamethasone on Sleep Related Breathing Disturbances in Patients With COPD at Altitude
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: MST for Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease|Depression|Movement Disorders|Major Depressive Disorder
Interventions: DEVICE: Magnetic Seizure Theapy (MagPro XP MST)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess the Safety of Immunotherapy Induction With Tremelimumab and Durvalumab Prior to Chemoradiotherapy and/or Resection in the Treatment
Status: UNKNOWN
Conditions: Stage III NSCLC
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|DRUG: Pemetrexed|DRUG: Cisplatin|RADIATION: chemo radiotherapy|PROCEDURE: Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Quantify the Range of Main Psychosocial Factors Affecting Patients and Caregivers in Their Daily Lives
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A|Haemophilia B|Haemophilia A With Inhibitors|Haemophilia B With Inhibitors|Relatives to/Carers of Patients
Interventions: OTHER: No treatment given
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety of MEDI2338 in Subjects With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BIOLOGICAL: MEDI2338|BIOLOGICAL: MEDI2338|BIOLOGICAL: MEDI2338|BIOLOGICAL: MEDI2338|BIOLOGICAL: MEDI2338|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Objective Examination and Rehabilitation Treatment of Patients With BPPV
Status: COMPLETED
Conditions: Postural Vertigo|Vertigo, Paroxysmal|Vertigo, Positional|Coordination Disorder, Developmental|Coordination and Balance Disturbances
Interventions: BEHAVIORAL: Neurorehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Specific PoC Testing of Coagulation in Patients Treated With DOAC 1
Status: UNKNOWN
Conditions: Anticoagulation With NOAC
Interventions: OTHER: anti-Xa activity point-of-care testing (aXa-POCT)|OTHER: ecarin clotting time point-of-care testing (ECT-POCT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Probiotics (LiveSpo Navax) in Preventing Respiratory Diseases in Children
Status: RECRUITING
Conditions: Respiratory Disease|Respiratory Infections in Children
Interventions: DRUG: 0.9% NaCl physiological saline|COMBINATION_PRODUCT: Probiotic 1|COMBINATION_PRODUCT: Probiotic 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial to Compare the Efficacy and Safety of a Combination Therapy of Ezetimibe and Rosuvastatin Versus Monotherapy of Rosuvastatin in Hypercholesterolemia Patients (I-ROSETTE Study)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Rosuvastatin|DRUG: Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative BNP: Epidemiological Patterns, Management Strategies and Cost Analysis of Care
Status: COMPLETED
Conditions: Myocardial Infarction Postoperative|Myocardial Injury|Death, Cardiac
Interventions: OTHER: Cardiac risk stratification using preoperative BNP measurement, followed by postoperative cardiac monitoring|OTHER: Use of traditional perioperative cardiac risk stratification only
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Conversion to Monotherapy Study With Keppra XR for Partial Seizures
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Keppra XR|DRUG: Keppra XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Para-aortic Lymphnodes Removal During Upfront Pancreaticoduodenectomy
Status: UNKNOWN
Conditions: Pancreas Cancer|Pancreaticoduodenal Lymphadenopathy|Pancreas Adenocarcinoma
Interventions: PROCEDURE: removal of para-aortic lymphnodes (PALN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: TraumaRelief App: A Pilot RCT Assessing Feasibility and Acceptability
Status: NOT_YET_RECRUITING
Conditions: Post-Traumatic Stress Disorder (PTSD)
Interventions: BEHAVIORAL: Application Plus Online Therapist Support Group|BEHAVIORAL: Application Only Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of Single Dose Ilofotase Alfa in Hypophosphatasia
Status: COMPLETED
Conditions: Hypophosphatasia
Interventions: BIOLOGICAL: Ilofotase Alfa, 0.8 mg/kg|BIOLOGICAL: Ilofotase Alfa, 3.2 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antenatal Tranexamic Acid in Women With Symptomatic Placenta Previa
Status: UNKNOWN
Conditions: Placenta Previa
Interventions: DRUG: Tranexamic acid tablets|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Post-Prandial Metabolic Effects of Oligomalt in Adults With T2D and in HAO
Status: COMPLETED
Conditions: Dietary Supplement
Interventions: DIETARY_SUPPLEMENT: Oligomalt|DIETARY_SUPPLEMENT: maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Meta-analysis of the Nordic Dietary Pattern on Cardiometabolic Risk and Cardiovascular Outcomes
Status: UNKNOWN
Conditions: Body Weight|Obesity|Overweight and Obesity|Obesity, Abdominal|Hypertension|Hyperlipidemias|Cardiovascular Diseases|Coronary Heart Disease|Stroke|Mortality|Dyslipidemias|Diabetes|PreDiabetes|Insulin Tolerance|Dysglycemia|Metabolic Syndrome
Interventions: OTHER: Nordic diet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p