pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of BTDS (Buprenorphine Transdermal System) and Placebo in Osteoarthritic Pain
Status: COMPLETED
Conditions: Pain|Osteoarthritis
Interventions: DRUG: Placebo|DRUG: Buprenorphine Transdermal System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Blind Cross-over Dose Response Study in Subjects of Two Inhalers of Salmeterol and Fluticasone Propionate
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Salmeterol|DRUG: fluticasone propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aprepitant- and Olanzapine- Containing Anti-emetic Regimens With High Dose Melphalan
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: DRUG: o Aprepitant 125 mg orally one hour prior to chemotherapy on Day -1 and 80 mg orally on Days 0 and +1|DRUG: Olanzapine10 mg orally daily on Days -1,0,+1 and +2|DRUG: Aprepitant plus Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cervical Preparation Before Dilation and Evacuation
Status: COMPLETED
Conditions: Abortion, Induced
Interventions: OTHER: Mifepristone|DRUG: misoprostol|DEVICE: Osmotic dilators|OTHER: placebo|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of One Day Discharge After Laparoscopic Appendectomy for Uncomplicated Appendicitis in Children.
Status: COMPLETED
Conditions: Appendicitis Acute
Interventions: PROCEDURE: Laparoscopic Appendectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety and Efficacy Study of LB80380 in the Treatment-naive Patients of Chronic Hepatitis B
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: LB80380|DRUG: Entecavir 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxaloacetate in Myasthenia Gravis
Status: UNKNOWN
Conditions: Myasthenia Gravis
Interventions: DRUG: Oxaloacetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: No-worry Baby Project
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus in Pregnancy|Gestational Hypertension|Thyroid Disease Pregnancy|Obesity|Anemia in Pregnancy|Complications, Pregnancy|Depression|Obstetric Labor Complications|Asthma|Allergic Disorder|Immune System Diseases|Neurodevelopmental Disorders|Reproductive Disorder
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Resourcefulness Training and Decentering on Self-Management in Caregivers of Technology Dependent Children
Status: COMPLETED
Conditions: Caregiver|Mindfulness|Mechanical Ventilation Pressure High|Gastrostomy|Chronic Illness
Interventions: BEHAVIORAL: Resourcefulness Training|BEHAVIORAL: Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness and Safety of the of Guaifenesin, Doxylamine Succinate and Hydrochloride Etafedrine Syrup in Improvement of Symptoms Resulting From Acute Respiratory Infections.
Status: UNKNOWN
Conditions: Upper Airway Infections
Interventions: DRUG: EMS Expectorant|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neobladder Posterior Wall Suspended With Round Ligament of Uterus
Status: COMPLETED
Conditions: Female|Bladder Cancer|Radical Cystectomy|Neobladder|Posterior Wall Suspended With Round Ligament of Uterus
Interventions: PROCEDURE: rONB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test How Itraconazole Influences the Amount of BI 730357 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 730357|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Restoring Emotion Regulation Networks in Depression Vulnerability
Status: COMPLETED
Conditions: Major Depression
Interventions: BEHAVIORAL: Attentional Bias Modification|BEHAVIORAL: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 3 Trial to Evaluate the Efficacy and Safety of DKP21102_B Added on to DKP21102_A Compared With DKP21102_A
Status: NOT_YET_RECRUITING
Conditions: Dyslipidemias
Interventions: DRUG: DKP21102_C|DRUG: DKP21102_B|DRUG: DKP21102_A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Evaluating the Safety of Lactobacillus Probiotic in Children With Drug Resistant Epilepsy
Status: RECRUITING
Conditions: Drug Resistant Epilepsy
Interventions: DRUG: Lactobacillus-Based Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Parenting Young Children Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Parenting|Parent-Child Relations|Opioid Misuse|Opioid Use Disorder|Executive Function|Stress|Depression|Parenting Self-efficacy
Interventions: BEHAVIORAL: Family Check-Up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Vyvanse in Adults With Attention-Deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention-Deficit/Hyperactivity Disorder
Interventions: DRUG: SPD489 (Lisdexamfetamine dimesylate)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of a Marketed Lubricated Eye Drop in Soft Contact Lens Wearers Who Experience Ocular Dryness
Status: COMPLETED
Conditions: Contact Lens Wear
Interventions: OTHER: FID 112903
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acetaminophen Use in Labor - Does Use of Acetaminophen Reduce Neuraxial Analgesic Drug Requirement During Labor?
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Acetaminophen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dual RElease Hydrocortisone Versus conventionAl Glucocorticoid replaceMent Therapy in Hypocortisolism (DREAM)
Status: COMPLETED
Conditions: Primary Adrenal Insufficiency|Secondary Adrenal Insufficiency
Interventions: DRUG: Plenadren|DRUG: Conventional glucocorticoid therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Comparing Heparin and Protamine Fixed and Titrated Doses in Cardiac Surgery With Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Cardiac Surgery|Cardiopulmonary Bypass|Anticoagulation
Interventions: DRUG: Heparin fixed doses|DRUG: PO continuous infusion of Protamine|DRUG: Heparin and protamine titration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reduction of Trauma-induced Intrusions and Amygdala Hyperreactivity Via Non-invasive Brain Stimulation
Status: UNKNOWN
Conditions: Intrusive Thoughts|Post Traumatic Stress Disorder
Interventions: DEVICE: iTBS|DEVICE: Placebo iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of ATNC05 in Treatment of Atypical Facial Pain
Status: WITHDRAWN
Conditions: Atypical Facial Pain|Persistent Idiopathic Facial Pain|Atypical Trigeminal Neuralgia|Neuropathic Orofacial Pain|Neuropathic Facial Pain
Interventions: DRUG: ATNC05|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OSE2101 Versus Chemotherapy in HLA-A2 Positive Patients With Advanced NSCLC After Immune Checkpoint Inhibitor Failure
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: BIOLOGICAL: OSE2101|DRUG: Docetaxel|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between Urine Iodine, Urine Bisphenol A and Autoimmune Thyroid Disease in Reproductive Women
Status: UNKNOWN
Conditions: The Effect of Iodine and BPA on AITD in Reproduction Women
Interventions: OTHER: urinary iodine and urine BPA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Insomnia Prevention in Children With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Pediatric Acute Lymphoblastic Leukemia|Leukemia|Acute Lymphoblastic Leukemia
Interventions: BEHAVIORAL: Sleep ALL Night
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Study of Unasyn-S 12g/Day for Community Acquired Pneumonia (CAP)
Status: COMPLETED
Conditions: Pneumonia, Bacterial
Interventions: DRUG: ampicillin sodium/sulbactam sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daratumumab for Chemotherapy-Refractory Minimal Residual Disease in T Cell ALL
Status: RECRUITING
Conditions: T-cell Acute Lymphoblastic Leukemia
Interventions: DRUG: Daratumumab / Hyaluronidase Injection|DRUG: Daratumumab / Hyaluronidase Injection|DRUG: Daratumumab / Hyaluronidase Injection|DRUG: Daratumumab / Hyaluronidase Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of EDG-5506 in Children and Adolescents With Duchenne Muscular Dystrophy Previously Treated With Gene Therapy (FOX)
Status: RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: EDG-5506 Dose 1|DRUG: EDG-5506 Dose 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Underlying Causes of Low Vitamin K Status in Hemodialysis Patients
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic
Interventions: DIETARY_SUPPLEMENT: Menakinon 7|DIETARY_SUPPLEMENT: Diet rich in vitamin K
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Micafungin Lock Therapy
Status: TERMINATED
Conditions: Catheter-Related Fungal Infections
Interventions: DRUG: Micafungin lock therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Everolimus in Patients With Metastatic Renal Cell Carcinoma Following Progression on Prior Bevacizumab Treatment
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MET/VEGFR2 Inhibitor GSK1363089 and Erlotinib Hydrochloride or Erlotinib Hydrochloride Alone in Locally Advanced or Metastatic NSCLC That Has Not Responded to Previous Chemotherapy
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: MET/VEGFR2 inhibitor Foretinib|DRUG: erlotinib hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Immunity Persistence Study of Enterovirus 71 Inactivated Vaccine (Vero Cell)
Status: NOT_YET_RECRUITING
Conditions: Hand, Foot and Mouth Disease
Interventions: BIOLOGICAL: Experimental Vaccine|BIOLOGICAL: Control Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of Lumen Expansion After Thrombus Extraction in Primary Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Acute ST Elevation Myocardial Infarction
Interventions: DEVICE: Thrombus aspiration (Intravascular Ultrasound catheter (Boston))
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Active Cycle of Breathing Technique and Pursed Lip Breathing With TheraPep
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease Exacerbation
Interventions: BEHAVIORAL: Thera PEP|BEHAVIORAL: ACBT and PLB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Desvenlafaxine Sustained Release (DVS SR) in Adult Female Outpatients With Fibromyalgia
Status: TERMINATED
Conditions: Fibromyalgia
Interventions: DRUG: Desvenlafaxine Sustained Release (DVS SR)|DRUG: Lyrica® (Pregabalin)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fundamental Asynchronous Stimulus Timing Sound Coding Study
Status: COMPLETED
Conditions: Sensorineural Hearing Loss
Interventions: DEVICE: Experimental sound coding strategy (FAST)|DEVICE: Commercially available ACE sound coding strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Performance of Paracentesis in Medical Residency Training
Status: COMPLETED
Conditions: Ascites|Cirrhosis
Interventions: BEHAVIORAL: Residency Program Teaching|BEHAVIORAL: Lecture|OTHER: Pocket Card Reference|BEHAVIORAL: Pager
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Study of SS1(dsFv)-PE38 (SS1P) Anti-Mesothelin Immunotoxin in Advanced Malignancies: IV Infusion QOD x Six Doses
Status: WITHDRAWN
Conditions: Neoplasms
Interventions: DRUG: SS1(dsFv)-PE38 (SS1P) Anti-Mesothelin Immunotoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetic Comparability of CC-93538 From Two Different Drug Concentrations in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: CC-93538|DRUG: CC-93538
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Assessment of a Weight-Gain Agent for the Treatment of Olanzapine-Associated Anti-Obesity Agent in Patients With Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder, and Bipolar I Disorder
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorders|Bipolar Disorder
Interventions: DRUG: Sibutramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Multiple Myeloma Who Have Undergone Stem Cell Transplantation
Status: COMPLETED
Conditions: Refractory Multiple Myeloma|Stage I Multiple Myeloma|Stage II Multiple Myeloma|Stage III Multiple Myeloma
Interventions: BIOLOGICAL: autologous immunoglobulin idiotype-KLH conjugate vaccine|BIOLOGICAL: sargramostim|BIOLOGICAL: aldesleukin|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-Dose Study of SHR-1314 in Subjects With Moderate-to-severe Plaque Psoriasis
Status: COMPLETED
Conditions: Moderate-to-severe Chronic Plaque Psoriasis
Interventions: BIOLOGICAL: SHR-1314|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amodiaquine-Artesunate & Artemether-Lumefantrine Efficacy in Burkina Faso
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Amodiaquine-Artesunate|DRUG: Artemether-lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Acute Effects of Oleic Acid Enriched-diets on Lipids, Insulin Sensitivity and Serum Inflammatory Markers
Status: COMPLETED
Conditions: Lipid Profile
Interventions: DIETARY_SUPPLEMENT: The acute effects of dietary fat on lipid profile, insulin sensitivity and inflammatory markers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Low-dose Rituximab in the Treatment of Refractory Myasthenia Gravis
Status: UNKNOWN
Conditions: Refractory Myasthenia Gravis|Rituximab
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Ketamine for Late-Life Depression and Suicidal Ideation
Status: WITHDRAWN
Conditions: Depression|Suicide|Suicidal Ideation
Interventions: DRUG: Ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Investigate the Pharmacokinetic Drug Interaction and Safety of CKD-501, D759 and D150 (CKD-393)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: CKD 501|DRUG: D759, D150|DRUG: CKD-501, D759, D150
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of CNTX-6970 in Subjects With Knee Osteoarthritis Pain.
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: CNTX-6970|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: XIENCE 90: A Safety Evaluation of 3-month DAPT After XIENCE Implantation for HBR Patients.
Status: COMPLETED
Conditions: Coronary Artery Lesions
Interventions: DEVICE: XIENCE|DRUG: DAPT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiwave Locked System Laser for Patients With Bell's Palsy.
Status: UNKNOWN
Conditions: Facial Paralyses, Idiopathic|Laser Therapy|Bell Palsy
Interventions: OTHER: Photobiomodulation therapy (laser therapy)|OTHER: Facial massage and facial expression exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Berodual® Respimat® vs Metered Dose Inhaler in Patients With Chronic Obstructive Pulmonary Disease
Status: TERMINATED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Berodual® Respimat® inhaler|DRUG: Berodual® metered dose inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain and Anxiety Reduction Using a Vibrating Eye Massage Device With Relaxing Nature Sounds
Status: COMPLETED
Conditions: Behavior, Child|Dental Anxiety|Anesthesia, Local
Interventions: BEHAVIORAL: Evaluation of the effectiveness of eye massage device producing both vibrations and nature sounds distraction in the management of anxious pediatric patients during inferior alveolar nerve.|BEHAVIORAL: Evaluation of the effectiveness of eye massage device producing vibratory stimulations distraction in the management of anxious pediatric patients during inferior alveolar nerve.|BEHAVIORAL: Evaluation of the effectiveness of basic behavior guidance techniques without using any type of distraction aids in the management of anxious pediatric patients during inferior alveolar nerve.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Vitamin D Supplementation on Hepcidin Levels and Transfusion Requirements in Surgical and Septic Patients
Status: UNKNOWN
Conditions: Systemic Inflammatory Response Syndrome|Sepsis|Surgical Injuries
Interventions: DIETARY_SUPPLEMENT: enteral supplementation with vitamin D|OTHER: blood collection 3mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II/III Study of SPH4336 Combined With Letrozole vs Placebo Combined With Letrozole in First-line Treatment of Breast Cancer
Status: RECRUITING
Conditions: Locally Advanced or Metastatic Breast Cancer
Interventions: DRUG: SPH4336 Tablets 400mg|DRUG: SPH4336 Tablets Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of High Dose Temozolomide to Treat Relapsed/Refractory Central Nervous System (CNS) Malignancy
Status: TERMINATED
Conditions: Central Nervous System Neoplasms|Neoplasm Metastasis
Interventions: DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Vitamin D in Women With PCOS and Sexual Dysfunction
Status: COMPLETED
Conditions: Female Sexual Dysfunction|Polycystic Ovary Syndrome
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DRUG: Hormonal contraception
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression
Status: COMPLETED
Conditions: Treatment-resistant Depression
Interventions: DRUG: Esketamine (Intranasal Spray)|DRUG: Duloxetine (Oral Antidepressant)|DRUG: Escitalopram (Oral Antidepressant)|DRUG: Sertraline (Oral Antidepressant)|DRUG: Venlafaxine Extended Release (XR) (Oral Antidepressant)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Bacillus Coagulans in Adults With With Functional Constipation
Status: COMPLETED
Conditions: Constipation - Functional
Interventions: DIETARY_SUPPLEMENT: Bacillus coagulans group|DIETARY_SUPPLEMENT: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MicroRNA and MicroRNA Inhibitors Socket Study, Pilot Clinical Trial
Status: WITHDRAWN
Conditions: Tooth Extraction Status Nos
Interventions: PROCEDURE: tooth extraction|RADIATION: CBCT scan|DRUG: Anesthesia|OTHER: clinical measurements|DRUG: Biodegradable sponge (type I bovine collagen)|DRUG: 10µg of pSil-miR200c|PROCEDURE: cross mattress suture|DRUG: 10µg of PMIS miR200a plasmids|DRUG: 5µg of pSil-miR200c and 5µg of PMIS miR200a|PROCEDURE: Blood|OTHER: Photos/videos|PROCEDURE: Wound fluid|PROCEDURE: saliva|RADIATION: periapical xray|OTHER: PVS impression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase III Study of BD0801 Combined With Chemotherapy in Recurrent, Platinum-resistant Epithelial Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: BD0801|DRUG: Paclitaxel|DRUG: Placebo|DRUG: Topotecan|DRUG: doxorubicin liposome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Discovering Patterns in the Gut Microbiota Associated With the Risk of Stroke and the Outcome After a Stroke and Integration of These Data With Genomic Information to Find New Drug Targets and New Treatments to Improve Neurological Evolution and Functional Status of Stroke Patients.
Status: UNKNOWN
Conditions: Ischemic Stroke
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: First in Human Safety Study of FX-322 in Adults Undergoing Cochlear Implantation
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DRUG: FX-322|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effect of Insulin Glulisine Compared to Insulin Aspart and Insulin Lispro When Administered by Continuous Subcutaneous Insulin Infusion (CSII) on Specific Pump Parameters in Patient With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Insulin glulisine|DRUG: Insulin lispro|DRUG: Insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Anti-KIR Monoclonal Antibody as Maintenance Treatment in Acute Myeloid Leukemia (EFFIKIR)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: IPH2102 at 0.1 mg/kg|DRUG: IPH2102 at 1 mg/kg|DRUG: Placebo (normal saline solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Oral Semaglutide Versus Placebo in Subjects With Type 2 Diabetes Mellitus Treated With Insulin
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: semaglutide|DRUG: semaglutide|DRUG: semaglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Swiss Multi-centre, Randomized, Placebo Controlled Trial of Pregabalin for Prevention of Persistent Pain in High Risk Patients Undergoing Breast Cancer Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Persistent Postoperative Pain
Interventions: DRUG: Pregabalin|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiolabeled Monoclonal Antibody and Combination Chemotherapy Before Stem Cell Transplant in Treating Patients With High-Risk Lymphoid Malignancies
Status: COMPLETED
Conditions: Recurrent B-Cell Non-Hodgkin Lymphoma|Recurrent Hodgkin Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent T-Cell Non-Hodgkin Lymphoma|Refractory B-Cell Non-Hodgkin Lymphoma|Refractory Hodgkin Lymphoma|Refractory Mantle Cell Lymphoma|Refractory T-Cell Non-Hodgkin Lymphoma
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Carmustine|DRUG: Cytarabine|DRUG: Etoposide|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan|PROCEDURE: Peripheral Blood Stem Cell Transplantation|RADIATION: Yttrium Y 90 Anti-CD45 Monoclonal Antibody BC8
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Naproxen to Sumatriptan for Emergency Headache Patients
Status: COMPLETED
Conditions: Migraine|Tension-type Headache|Primary Headache Disorder
Interventions: DRUG: Sumatriptan 100 mg|DRUG: Naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Leuprolide to Improve Immune Function After Allogeneic Bone Marrow Transplantation
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Acute Lymphocytic Leukemia|Acute Myelogenous Leukemia|Chronic Myelogenous Leukemia|Chronic Myelomonocytic Leukemia
Interventions: PROCEDURE: First Allogeneic Bone Marrow Transplant (BMT)|DRUG: Leuprolide|DRUG: 18F FLT|DRUG: Cyclophosphamide|DRUG: Methotrexate|DRUG: Tacrolimus|RADIATION: Total Body Irradiation|DRUG: Busulfan|DRUG: Fludarabine|PROCEDURE: Second Allogeneic Bone Marrow Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Compare Safety and Pharmacokinetic Characteristics of CKD-337
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DRUG: Active Comparator(Atorvastatin Calcium Trihydrate+Fenofibrate)|DRUG: Test drug(CKD-337)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRP as Adjuvant Treatment to CTR for Severe CTS Tunnel Syndrome
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome|PRP
Interventions: DEVICE: Carpal Tunnel Release with Platelet-Rich Plasma|PROCEDURE: Carpal Tunnel Release without Platelet-Rich Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety of Pre-TURBT Intravesical Instillation of Escalating Doses of TC-3 Gel and MMC in NMIBC Patients
Status: COMPLETED
Conditions: Bladder Cancer|Neoplasms|Urinary Bladder Diseases|Urologic Diseases
Interventions: DRUG: 120 mg MMC in 90ml gel|DRUG: 140 mg MMC in 90ml gel|DRUG: 160 mg MMC in 90ml gel|DRUG: 120 mg MMC in 60ml gel|DRUG: 140 mg MMC in 60ml gel|DRUG: 160 mg MMC in 60ml gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Assess The Ability Of Tramadol, Naproxen And Oxycodone To Affect The Pain Thresholds Of Patients With Osteoarthritis Of The Thumb
Status: COMPLETED
Conditions: Osteoarthritis Thumbs
Interventions: DRUG: Placebo|DRUG: Oxycodone|DRUG: Tramadol|DRUG: Naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Peripheral Stem Cell Transplantation to Prevent Neutropenia in Patients Receiving Chemotherapy for Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Lymphoma|Neutropenia
Interventions: BIOLOGICAL: epoetin alfa|BIOLOGICAL: filgrastim|BIOLOGICAL: recombinant flt3 ligand|BIOLOGICAL: recombinant interleukin-3|BIOLOGICAL: sargramostim|PROCEDURE: in vitro-treated peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LVSP vs RVP in Patients With AV Conduction Disorders
Status: RECRUITING
Conditions: Cardiac Pacing|Pacing-Induced Cardiomyopathy|Conduction System Pacing|Left Ventricular Septal Pacing|Atrioventricular Block
Interventions: PROCEDURE: Left ventricular septal pacing|PROCEDURE: Right ventricular pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Forming at Prosthetic Surfaces. Fingerprint2
Status: UNKNOWN
Conditions: Osteo Arthritis
Interventions: DEVICE: Component for acetabulum (Regenerex RingLoc cup)|DEVICE: Components for the acetabulum (Lubinus cross linked cup)|DEVICE: Arthroplasty components are for the femur (Cemented Lubinus SP II stem)|DEVICE: Arthroplasty components are for the femur (Corail stem)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SMS-based Lifestyle Intervention for Patients With Liver Cirrhosis With Previous Hepathic Encephalopathy
Status: TERMINATED
Conditions: Liver Cirrhosis, Alcoholic
Interventions: BEHAVIORAL: Supervised exercise|OTHER: Usual Care|BEHAVIORAL: SMS-messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sublingual Atropine Bioequivalence by Route of Administration (SABER)
Status: COMPLETED
Conditions: Atropine Bioequivalence
Interventions: DRUG: Atropine Sulfate Ophthalmic Solution USP, 1%|DRUG: Atropine Sulfate Injection, USP 8 mg/20 mL (0.4 mg/mL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Transarterial Chemoinfusion (TAI) Combine Stereotactic Body Radiation Therapy (SBRT) in Unresectable Hepatocellular Carcinoma (HCC)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: COMBINATION_PRODUCT: TAI combine SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medroxyprogesterone Acetate Plus Atorvastatin in Young Women With Early Endometrial Carcinoma and Atypical Endometrial Hyperplasia
Status: RECRUITING
Conditions: Atypical Endometrial Hyperplasia|Endometrial Carcinoma Stage I
Interventions: DRUG: Medroxyprogesterone acetate + Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quetiapine vs. Placebo in Alcohol Relapse Prevention - a Pilot Study
Status: COMPLETED
Conditions: Alcohol Relapse Prevention|Alcoholism|Alcohol Drinking|Alcohol Consumption|Alcohol Abuse
Interventions: DRUG: Seroquel®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of GSK2292767 in Healthy Participants Who Smoke Cigarettes
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: GSK2292767 50 μg|DRUG: GSK2292767 500 μg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Danhong Injection in the Treatment of Unstable Angina Pectoris
Status: COMPLETED
Conditions: Unstable Angina Pectoris
Interventions: DRUG: Danhong injection|OTHER: Standard medical care|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prolongation of a Clinical Study to Evaluate the Efficacy of an Aqueous Gel Containing 2% (w/w) of Cidofovir, Directly Applied on the Cervix Exhibiting High Grade Squamous Intraepithelial Lesions.
Status: COMPLETED
Conditions: High Grade Cervical Epithelial Neoplasia (CIN2+)
Interventions: DRUG: Cidofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sleep Disruption on Drug Response
Status: RECRUITING
Conditions: Low Back Pain, Recurrent|Healthy
Interventions: DRUG: Within-Subject test of blinded study medication
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Protocol for the Treatment of Metastatic Ewing Sarcoma
Status: COMPLETED
Conditions: Ewing's Sarcoma (ES)
Interventions: DRUG: TEMIRI|DRUG: ADM|DRUG: IFO|DRUG: CYC|DRUG: ETO|DRUG: BUMEL|DRUG: VIN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Statin Therapy in Primary Sclerosing Cholangitis (PSC): a Multi-omics Study
Status: RECRUITING
Conditions: Primary Sclerosing Cholangitis|Inflammatory Bowel Diseases
Interventions: DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Aerosolized Randomized Iloprost Study II (AIR - II) Long-Term Safety, Tolerability, and Clinical Effects of Iloprost Inhalation in Patients With Primary or Secondary Pulmonary Hypertension
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Ventavis (Iloprost, BAYQ6256)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short and Long Term Treatment With 4-AP in Ambulatory SMA Patients
Status: COMPLETED
Conditions: Spinal Muscular Atrophy
Interventions: DRUG: 4-aminopyridine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glutathione-rich Foods for Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: OTHER: GSH Foods|OTHER: Nutrition education about glutathione sources in the diet|OTHER: Standard of care nutrition education for type 2 diabetes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation (FMT) of FMP30 in Relapsing-Remitting Multiple Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: FMP30 Donor Stool|PROCEDURE: Fecal Microbiota Transplantation (FMT) of FMP30 Donor Stool|OTHER: Observational Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Hydrolysed Red Ginseng Extract on Dry Eye
Status: UNKNOWN
Conditions: Dry Eye
Interventions: DIETARY_SUPPLEMENT: Hydrolysed Red Ginseng Extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Immunotherapy in Rare Cancers Under InvesTigation
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Biliary Tract Cancer|Neuroendocrine Tumors|Female Reproductive System Neoplasm|MSI-H Solid Malignant Tumor
Interventions: DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Inhaled Carbon Monoxide to Treat Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: inhaled carbon monoxide|OTHER: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Brain and Gut Responses to Intragastric Administration of FODMAPs in Healthy Subjects and Patients With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Fructans|DIETARY_SUPPLEMENT: Glucose|DIETARY_SUPPLEMENT: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: PROPER Trial of Pain and Inflammation After Knee Arthroscopy
Status: TERMINATED
Conditions: Meniscus Tear|Meniscus Lesion|Cartilage Injury
Interventions: DRUG: Ceftriaxone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Acceptability of Problem Management Plus (PM+) for Prisoners in the Netherlands - a Pilot RCT
Status: NOT_YET_RECRUITING
Conditions: Anxiety Disorders|Psychological Distress|Depressive Disorder
Interventions: BEHAVIORAL: Problem Management Plus (PM+)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Weight-loss Diet Decision-making Based on Initial Gut Metabolic Modules (GMMs)
Status: RECRUITING
Conditions: Weight Loss
Interventions: DIETARY_SUPPLEMENT: plant-based Low carbohydrate diet|DIETARY_SUPPLEMENT: plant-based Low low fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Cauliflower Mushroom Extract on Promotion of Immunity
Status: COMPLETED
Conditions: Immunity
Interventions: DIETARY_SUPPLEMENT: Cauliflower Mushroom extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical and Neurobiological Effects of Cannabis Dependence in Young Adults
Status: COMPLETED
Conditions: Cannabis Dependence|Cannabis Withdrawal
Interventions: DRUG: rimonabant|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Patient-Driven Analgesic Protocol Selection for Post-Cesarean Pain Management
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: OTHER: No choice given|OTHER: Choice given|DRUG: Ibuprofen|DRUG: Acetaminophen|DRUG: Gabapentin|DRUG: Morphine (low)|DRUG: Morphine (med)|DRUG: Morphine (high)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Pharmaco/Behavior Therapy in Adolescent Smokers
Status: COMPLETED
Conditions: Nicotine Dependence|Nicotine Use Disorder
Interventions: DRUG: Bupropion SR|BEHAVIORAL: Contingency Management|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Radiation Therapy in Treating Younger Patients Who Are Undergoing an Autologous Stem Cell Transplant for Newly Diagnosed Gliomas
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: O6-benzylguanine|DRUG: busulfan|DRUG: temozolomide|PROCEDURE: adjuvant therapy|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: conventional surgery|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP015K
Status: COMPLETED
Conditions: Healthy Subjects|Pharmacokinetics of ASP015K
Interventions: DRUG: ASP015K|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effect of Timing of a Post-exercise Oral Glucose Tolerance Test on Glycaemic Control.
Status: SUSPENDED
Conditions: Area Under Curve [N06.850.520.830.200]
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Rest|BEHAVIORAL: Delay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Short vs Long Duration Dual Antiplatelet Therapy in Patients Undergoing Lower Extremity Endovascular Revascularization
Status: WITHDRAWN
Conditions: Peripheral Arterial Disease|Endovascular Procedures
Interventions: DRUG: Aspirin|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plasmapheresis for Nephrogenic Fibrosing Dermopathy (NFD)/Nephrogenic Systemic Fibrosis (NSF)
Status: TERMINATED
Conditions: Nephrogenic Fibrosing Dermopathy|Nephrogenic Systemic Fibrosis
Interventions: PROCEDURE: Plasmapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Neurostimulation for the Treatment of Neurosensory Abnormalities in CL Wearers (INTAC)
Status: WITHDRAWN
Conditions: Contact Allergy|Neuropathic Pain
Interventions: DEVICE: TrueTear™ intranasal neurostimulator (ITN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mobile App Logging for Diabetes in Pregnancy
Status: NOT_YET_RECRUITING
Conditions: Gestational Diabetes Mellitus in Pregnancy|Type 2 Diabetes
Interventions: BEHAVIORAL: OneTouch Reveal application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduce Nonsteroidal Antiinflammatory Drugs Doses for Analgesia After Sternotomy
Status: UNKNOWN
Conditions: Cardiac Surgery|Post-operative Pain
Interventions: DRUG: Ketoprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT