pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Stroke Vision App: A Screening Tool for Visual Stroke
Status: UNKNOWN
Conditions: Eye Abnormalities|Stroke
Interventions: PROCEDURE: Formal Perimetry (Goldman or Octopus visual Field)|PROCEDURE: Albert's visual inattention test|PROCEDURE: Star cancellation visual inattention test|PROCEDURE: Visual field assessment to confrontation|PROCEDURE: Visual inattention assessment to bilateral stimuli|DEVICE: Digital tumbling E visual accuity assessment|DEVICE: Digital visual field assessment|DEVICE: Digital line crossing assessment|DEVICE: Digital shape cancellation assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: PD1 Antibody (Toripalimab), GEMOX and Lenvatinib Neoadjuvant Treatment for Resectable Intrahepatic Cholangiocarcinoma With High-risk Recurrence Factors
Status: UNKNOWN
Conditions: Cholangiocarcinoma, Intrahepatic
Interventions: DRUG: neoadjuvant treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Infectivity, Safety and Immunogenicity of a Recombinant Live-Attenuated Respiratory Syncytial Virus Vaccine (RSV LID cp ΔM2-2) in RSV-Seronegative Infants 6 to 24 Months of Age
Status: TERMINATED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSV LID cp ΔM2-2 Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Single Agent Chemotherapy +/- Nivolumab in Patients With Advanced Squamous or Non-squamous NSCLC With Primary Resistance to Prior PD-1 or PDL-1 Inhibitor
Status: TERMINATED
Conditions: Non-Squamous Non-Small Cell Lung Cancer (NSCLC)|Adenocarcinoma of the Lung|Lung Cancer|Squamous Cell Lung Cancer
Interventions: DRUG: Docetaxel|DRUG: Nivolumab|DRUG: Gemcitabine|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anxiety, Stress and Sleep Problems in People With Early Onset Dementia
Status: NOT_YET_RECRUITING
Conditions: Early Onset Dementia|Young Onset Dementia|Stress|Distress, Emotional|Anxiety|Sleep Problem|Sleep|Insomnia
Interventions: BEHAVIORAL: young-D program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Tranexamic Acid on Blood Loss and Transfusion Requirements Following Open Femur Fracture Surgery
Status: WITHDRAWN
Conditions: Blood Loss Following Open Femur Fracture Surgery
Interventions: DRUG: Tranexamic acid (TXA)|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Product X92001327 vs RID Shampoo in Subjects With Head Lice
Status: COMPLETED
Conditions: Head Lice
Interventions: OTHER: X92001327|OTHER: RID shampoo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pimecrolimus Cream 1% Plus Topical Corticosteroid in Patients (2-17 Years of Age) With Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: Pimecrolimus plus topical corticosteroid (TCS)|DRUG: Pimecrolimus vehicle (Placebo) plus topical corticosteroid (TCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pomalidomide in Persons With Myeloproliferative-Neoplasm-Associated Myelofibrosis and RBC-Transfusion-Dependence
Status: COMPLETED
Conditions: Primary Myelofibrosis|MPN-associated Myelofibrosis
Interventions: DRUG: Pomalidomide 0.5 mg|DRUG: Placebo|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Quizartinib in Combination With Standard Therapies in Chinese Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: Quizartinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Prophylaxis to Prevent Obesity-Related Induction Complications in Nulliparae at Term 2.0
Status: NOT_YET_RECRUITING
Conditions: Obesity in Pregnancy|Labor Complication
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Thoracic OncoGeriatric Assessment (TOGA) Trials
Status: COMPLETED
Conditions: Thoracic Neoplasms|Lung Neoplasms|Esophagus Neoplasms|Pleural Neoplasms|Thymus Neoplasms
Interventions: BEHAVIORAL: TOGA Tools
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dry Needling of the M. Obliquus Capitis Inferior on Rotational Mobility and Headache Related Outcome Measures in CH.
Status: RECRUITING
Conditions: Neck Pain, Posterior|Headache|Mobility Limitation
Interventions: OTHER: Dry Needling|OTHER: Sham Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of the Live Oral Cholera Vaccine Candidate PXVX0200
Status: COMPLETED
Conditions: Cholera
Interventions: BIOLOGICAL: PXVX0200|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clozapine Versus Olanzapine as Treatment for Comorbid Psychotic Disorder and Substance Use Disorder
Status: UNKNOWN
Conditions: Psychosis|Substance Use Disorders
Interventions: DRUG: Clozapine|DRUG: Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Preliminary Efficacy of Oral Midostaurin (PKC412) in Relapsed or Refractory Pediatric Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia
Interventions: DRUG: midostaurin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Intervention in Food Allergy
Status: COMPLETED
Conditions: Food Allergy
Interventions: DIETARY_SUPPLEMENT: Citrus pectin with low DE|DIETARY_SUPPLEMENT: Apple pectin with high DE|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed Disodium or Erlotinib Hydrochloride as Second-Line Therapy in Treating Patients With Advanced Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Recurrent Non-Small Cell Lung Carcinoma|Stage IIIA Non-Small Cell Lung Cancer|Stage IIIB Non-Small Cell Lung Cancer|Stage IV Non-Small Cell Lung Cancer
Interventions: DRUG: Erlotinib Hydrochloride|DRUG: Pemetrexed Disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Impact of a Non-SLS Toothpaste Upon Oral Mucosal Desquamation
Status: COMPLETED
Conditions: Sloughing Skin|Mucosal Inflammation
Interventions: OTHER: Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Dexmedetomidine to Bupivacaine in Supraclavicular Brachial Plexus Block
Status: COMPLETED
Conditions: Dexmedetomidine|Bupivacaine|Supraclavicular Brachial Plexus Block
Interventions: DRUG: bupivacaine and dexmedetomidine.|DRUG: bupivacaine only|DRUG: bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy Study of Teriflunomide in Participants With Relapsing Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Placebo|DRUG: Teriflunomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bacterial Properties With LoFric® Catheters During Clean Intermittent Catheterization
Status: WITHDRAWN
Conditions: Neurogenic Bladder|Urinary Retention
Interventions: DEVICE: LoFric® catheters during clean intermittent catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Management Smartphone Application for Patients With Stage III-IV Head and Neck Cancer Undergoing Radiation Therapy
Status: COMPLETED
Conditions: Head and Neck Cancer|Pain|Lung Cancer|Esophageal Cancer
Interventions: BEHAVIORAL: Telephone-Based Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prediction of Anastomotic Complications and Recurrent Laryngeal Nerve Injury Based on Postoperative Early Endoscopic Evaluation
Status: RECRUITING
Conditions: Esophageal Neoplasm|Anastomotic Leak|Recurrent Laryngeal Nerve Injuries|Anastomotic Stenosis|Endoscopic Evaluation
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low-Dose Radiation Therapy to the Whole Liver With Gemcitabine and Cisplatin in IHC
Status: TERMINATED
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin|RADIATION: low dose radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Investigate the PK Profiles and Safety of CKD-385 in Healthy Volunteers Under Fed Conditions
Status: UNKNOWN
Conditions: Cardiovascular Diseases
Interventions: DRUG: Reference drug|DRUG: Test drug 1|DRUG: Test drug 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lactobacillus Plantarum 299v on Symptoms of Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Lactobacillus plantarum 299v|DRUG: Placebo comparator|OTHER: Run in period|OTHER: Wash - out period
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of an Apple Derived Fibre Supplement on Constipation
Status: UNKNOWN
Conditions: Constipation|Functional Gastrointestinal Disorders
Interventions: DIETARY_SUPPLEMENT: Apple derived fiber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Respiratory Muscle Stretching in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: respiratory muscle stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-line R-CVP vs R-CHOP Induction Immunochemotherapy for Indolent Lymphoma and R Maintenance.
Status: COMPLETED
Conditions: Follicular Lymphoma|Marginal Zone Lymphoma|Small Lymphocytic Lymphoma|Lymphoplasmacytic Lymphoma
Interventions: DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone 1|DRUG: Prednisone 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breakfast, Exercise and Metabolic Health in Healthy Women
Status: RECRUITING
Conditions: Metabolic Health|Appetitive Behavior|Energy Balance
Interventions: BEHAVIORAL: Fasted exercise|BEHAVIORAL: High protein breakfast exercise|BEHAVIORAL: High carbohydrate breakfast exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Leiden Nonischemic Cardiomyopathy Study
Status: COMPLETED
Conditions: Cardiomyopathy, Dilated|Tachycardia, Ventricular|Ventricular Fibrillation
Interventions: OTHER: Transthoracic echocardiography|OTHER: Exercise test|OTHER: 24-hour Holter electrocardiogram|OTHER: Contrast-enhanced magnetic resonance imaging|OTHER: 123-iodine metaiodobenzylguanidine imaging|OTHER: Blood samples|GENETIC: Genetic analysis|PROCEDURE: Invasive electrophysiological study|PROCEDURE: Endomyocardial biopsy|PROCEDURE: Intraoperative biopsy|PROCEDURE: Intraoperative mapping and/or ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ProTarget - A Danish Nationwide Clinical Trial on Targeted Cancer Treatment Based on Genomic Profiling
Status: RECRUITING
Conditions: Cancer|Tumors|Neoplasms|Neoplasia
Interventions: DRUG: Alectinib|DRUG: Atezolizumab|DRUG: Avelumab|DRUG: Axitinib|DRUG: Erlotinib|DRUG: Vemurafenib plus Cobimetinib (combination)|DRUG: Trastuzumab plus Pertuzumab (combination)|DRUG: Trastuzumab emtansine|DRUG: Vismodegib|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ADME Study of Acoziborole in Healthy Subjects
Status: COMPLETED
Conditions: Trypanosomiases, African
Interventions: DRUG: [14C]-acoziborole capsule, 240 mg containing NMT 9.25 kBq (250 nCi) 14C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating an Online Wellness Intervention for Greek Adolescents
Status: UNKNOWN
Conditions: Depressive Symptoms|Anxiety|Happiness
Interventions: BEHAVIORAL: Common Elements Toolbox|BEHAVIORAL: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Phase II Study of Concurrent Chemoradiation With Every 3 Week of Cisplatin vs With Weekly Cisplatin in Locally Advanced Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasophayngeal Carcinoma Between Stage II and IVb
Interventions: DRUG: cisplatin (3 weekly)|DRUG: cisplatin (weekly)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BioWave High-frequency Neurostimulation Versus TENS for the Treatment of Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Pain|Lumbar Pain Syndrome|Low Back Pain
Interventions: DEVICE: BioWave|DEVICE: TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aldosterone, Microvascular Function and Salt-sensitivity
Status: COMPLETED
Conditions: Abdominal Obesity|Metabolic Syndrome|Sodium-sensitivity|Insulin Resistance|Hypertension
Interventions: DIETARY_SUPPLEMENT: Low-sodium diet|DIETARY_SUPPLEMENT: High-sodium diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety Study of Loperamide Hydrochloride/Simethicone Chewable Tablet in Treatment of Acute Diarrhea With Abdominal Discomfort and Flatulence
Status: COMPLETED
Conditions: Diarrhea
Interventions: DRUG: Loperamide hydrochloride + simethicone chewable tablet|DRUG: Loperamide hydrochloride|DRUG: Loperamide hydrochloride + simethicone chewable placebo tablet|DRUG: Loperamide hydrochloride placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DeteCtiON and Stroke PreventIon by MoDEl ScRreenING for Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DIAGNOSTIC_TEST: Risk prediction model|DIAGNOSTIC_TEST: 14-days continuous ECG monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Tolerability of PF-06649751 in Parkinson's Disease Patients With Motor Fluctuations
Status: TERMINATED
Conditions: Parkinson's Disease With Motor Fluctuations
Interventions: DRUG: 1 mg QD to 15 mg QD PF-06649751|DRUG: 3 mg QD to 15 mg QD PF-06649751|DRUG: 7 mg QD to 15 mg QD PF-06649751|DRUG: 15 mg QD PF-06649751|DRUG: 1 mg QD to 7 mg QD PF-06649751 (if de-escalated in parent study)|DRUG: 3 mg QD to 7 mg QD PF-06649751 (de-escalated in parent study)|DRUG: 7 mg QD to 7 mg QD PF-06649751 (de-escalated in parent study)|DRUG: 15 mg QD de-escalated to 7 mg QD PF-06649751 in parent study remain at 7 mg QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Safety, Tolerability, and Clinical Activity of the Antibody-drug Conjugate, GSK2857916 Administered in Combination With Lenalidomide Plus Dexamethasone (Arm A), or in Combination With Bortezomib Plus Dexamethasone (Arm B) in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Belantamab mafodotin|DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug-Drug Interaction Study to Evaluate the Effect of Ripretinib on the Pharmacokinetics of a CYP2C8 Probe Substrate in Patients With Advanced GIST
Status: COMPLETED
Conditions: GIST - Gastrointestinal Stromal Tumor
Interventions: DRUG: Ripretinib|DRUG: Repaglinide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Telephone Intervention Program in Improving Depression, Coping, and Family Functioning in HIV-Infected Individuals and Caregivers
Status: COMPLETED
Conditions: HIV Infections
Interventions: BEHAVIORAL: FITT: Family Intervention - Telephone Tracking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Laryngeal Mask Airway Gastro on Patients Undergoing Endoscopic Retrograde Cholangiopancreatography for Pancreas and Bile Duct Disorders
Status: COMPLETED
Conditions: Bile Duct Disorder|Endocrine Pancreas Disorder
Interventions: PROCEDURE: Endoscopic Retrograde Cholangiopancreatography|OTHER: Interview|DEVICE: Laryngeal Mask Airway
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Learn if 27T51, a Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy, Administered Alone or in Combination is Safe and How Well it Works for Adult Participants With Recurrent or Treatment Resistant Ovarian Cancers
Status: RECRUITING
Conditions: Epithelial Ovarian Cancer|Primary Peritoneal Carcinoma|Fallopian Tube Cancer
Interventions: OTHER: 27T51|DRUG: Cemiplimab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Radiation Therapy for Severe-Acute-Respiratory-Syndrome-Coronavirus-2 (SARS-CoV-2), COVID-19
Status: COMPLETED
Conditions: Severe-Acute-Respiratory-Syndrome-Coronavirus-2 (SARS-CoV-2)
Interventions: RADIATION: Low Dose Radiation Therapy (LD-RT)|OTHER: Sham irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Impact of Breathing Exercises and Meditation on Quality of Life in Dry Eye Disease Patients: A Pilot Study
Status: UNKNOWN
Conditions: Depression|Quality of Life|Dry Eye|Anxiety|Sleep
Interventions: OTHER: SKY + ASTM + usual care|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Peroperative Suction Drain Usage in Arthroscopic Knee Surgery
Status: COMPLETED
Conditions: Chondropathy|Knee Effusion|Knee Hemarthrosis
Interventions: DEVICE: Suction drain|DEVICE: No suction drain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Tranexamic Acid Reducing Intraoperative Blood Loss in Huge Meningiomas Resection
Status: RECRUITING
Conditions: Tranexamic Acid|Intraoperative Blood Loss|Meningioma
Interventions: DRUG: Continous infusion|DRUG: Single infusion|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I/II Study of Carboplatin and Etoposide With or Without Obatoclax in Extensive-stage Small Cell Lung Cancer (ES-SCLC)
Status: COMPLETED
Conditions: Extensive-stage Small Cell Lung Cancer
Interventions: DRUG: Obatoclax|DRUG: Carboplatin/etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Nano-iron Supplement to Safely Combat Iron Deficiency and Anaemia in Young Children: a Doubleblind Randomised Controlled Trial
Status: COMPLETED
Conditions: Iron Deficiency, Anaemia in Children
Interventions: DIETARY_SUPPLEMENT: IHAT|DIETARY_SUPPLEMENT: Ferrous Sulphate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Follow on Study From RE-ALIGN
Status: TERMINATED
Conditions: Thromboembolism|Heart Valve Prosthesis
Interventions: DRUG: dabigatran etexilate low dose|DRUG: warfarin 5mg|DRUG: dabigatran etexilate intermediate dose|DRUG: warfarin 1mg|DRUG: dabigatran etexilate high dose|DRUG: warfarin 3mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Vitamin D3 on the Rate of Orthodontic Tooth Movement
Status: COMPLETED
Conditions: Tooth Position Anomalies
Interventions: PROCEDURE: Micro-osteoperforation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Rehabilitation Assistant Via Instant Messaging Communication to Promote Adherence to Rehabilitation After Reverse Shoulder Replacement
Status: RECRUITING
Conditions: Shoulder Osteoarthritis
Interventions: OTHER: Chatbot|OTHER: Standard car
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Neuromuscular and Aquatic Exercise Programs on Fall Risk and Physical Function in Geriatrics
Status: RECRUITING
Conditions: Geriatrics|Exercise Therapy|Fall|Physical Functional Performance
Interventions: BEHAVIORAL: Neuromuscular Exercise|BEHAVIORAL: Aquatic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ear Acupuncture Preventing Delayed Gastric Emptying.
Status: UNKNOWN
Conditions: Auricular Acupoint Embedding|Pancreaticoduodenectomy|Delayed Gastric Emptying
Interventions: OTHER: Ear Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of BAO-G Technique in TAAA Endovascular Repair
Status: ENROLLING_BY_INVITATION
Conditions: Aortic Aneurysm, Thoracoabdominal
Interventions: PROCEDURE: BAO-G
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Hormones in Postpartum Mood Disorders
Status: RECRUITING
Conditions: Postpartum Depression
Interventions: DRUG: Estradiol|OTHER: Placebo|DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transitional Treatment of Adolescents in Family Therapy
Status: COMPLETED
Conditions: Substance Abuse
Interventions: BEHAVIORAL: MTI, Minimal Transitional Intervention|BEHAVIORAL: GTI, Group Transitional Intervention|BEHAVIORAL: STI, Systems Transitions Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Efficacy and Safety of MMH-MAP in the Treatment of Cognitive Disorders in Patients With Ischemic Stroke in the Carotid Arteries
Status: COMPLETED
Conditions: Cognitive Disorders
Interventions: DRUG: MMH-MAP|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of MK0557 in Combination With Sibutramine or Orlistat (0557-015)(COMPLETED)
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: MK0557
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Cyclosporine Inhalation Solution (CIS) in Improving Bronchiolitis Obliterans Syndrome-Free Survival Following Lung Transplantation
Status: COMPLETED
Conditions: Lung Transplant
Interventions: DRUG: Cyclosporine Inhalation Solution (CIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment of Post-Ocriplasmin Therapy Vitreolysis Induced Subretinal Fluid With Eplerenone (Mineralocorticoid Antagonists)
Status: TERMINATED
Conditions: Vitreomacular Traction|Subretinal Edema
Interventions: DRUG: Eplerenone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnosed Advanced Ovarian, Fallopian Tube or Primary Peritoneal Cancer
Status: RECRUITING
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Bevacizumab|DRUG: IMNN-001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sublobar Resection for Adenocarcinoma in Situ/Minimally Invasive Adenocarcinoma Diagnosed by Intraoperative Frozen Section (ECTOP-1019)
Status: RECRUITING
Conditions: Lung Adenocarcinoma|Frozen Section|Sublobar Resection
Interventions: PROCEDURE: Sublobar Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Clinical Performance of BlockBuster vs Proseal-LMA in Unparalysed Patients Undergoing General Anesthesia
Status: COMPLETED
Conditions: Supraglottic Airway Device
Interventions: DEVICE: Blockbuster|DEVICE: Proseal-LMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Effectiveness of Different Airway Management Methods During Percutaneous Tracheostomy
Status: UNKNOWN
Conditions: Intubation, Intratracheal|Tracheostomy|Laryngeal Masks|Intensive Care Units
Interventions: PROCEDURE: Endotracheal Tube Insertion|PROCEDURE: Laryngeal Mask Insertion|PROCEDURE: Fiberoptic Bronchoscopy|PROCEDURE: Radial Artery Monitoring|DIAGNOSTIC_TEST: Anteroposterior chest x-ray|DIAGNOSTIC_TEST: Arterial Blood Gas Analyses|DRUG: Propofol Fresenius|DRUG: Rocuronium|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carmustine, Etoposide, Cyclophosphamide, and Stem Cell Transplant in Treating Patients With HIV-Associated Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma
Interventions: DRUG: carmustine|DRUG: cyclophosphamide|DRUG: etoposide|OTHER: pharmacological study|PROCEDURE: autologous hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase IV Study Investigating the Effects of Remifentanil Concentrations on Propofol Requirements for Loss of Consciousness, Response to Painful Stimuli, Bispectral Index and Associated Haemodynamic Changes
Status: COMPLETED
Conditions: Induction of Anaesthesia
Interventions: DRUG: Remifentanil|DRUG: Propofol|OTHER: Bispectral index
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Repetitive Transcranial Magnetic Stimulation in the Treatment of Phantom Limb Pain in Landmine Victims: ANTARES
Status: COMPLETED
Conditions: Phantom Limb Pain
Interventions: DEVICE: rTMS|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effects of EST and EPBD in Patients With Acute Biliary Pancreatitis
Status: UNKNOWN
Conditions: Acute Biliary Pancreatitis
Interventions: PROCEDURE: Endoscopic papillary balloon dilation|PROCEDURE: Endoscopic sphincterotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Femoral Nerve Catheters to Single Shot Femoral Nerve Blocks for Total Knee Replacement Surgery
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Femoral Nerve Catheters|DRUG: Single Shot Femoral Nerve Blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bipolar Versus Laser Enaculation of Prostate for >80gram Prostate .
Status: RECRUITING
Conditions: Bipolar TURP , Laser Enucleation in Management of Enlarged Prostate
Interventions: DEVICE: bipolar transurethral resection and Laser enaculation by holmium: YAG laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adoptive Cord Blood Immunotherapy for EBV, CMV, BKV and Adenovirus Reactivation/Infection or Prophylaxis
Status: RECRUITING
Conditions: Viral Infection
Interventions: BIOLOGICAL: CMV/AdV /EBV/BKV specific T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Pharmacokinetic Study of ER OROS Paliperidone in Pediatric Patients With Schizophrenia, Schizoaffective Disorder, or Schizophreniform Disorder
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorders
Interventions: DRUG: ER OROS paliperidone, paliperidone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rhinitis, Cognition and Driving Performance
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis|Driving Ability|Cognition
Interventions: DRUG: cetirizine 10 mg|DRUG: fluticasone furoate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: The Effect of Algae Dunaliella Bardawil on Psoriasis (2)
Status: WITHDRAWN
Conditions: Psoriasis
Interventions: DRUG: Alga Dunaliella Bardawil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone and Robotic-assisted Hysterectomy
Status: COMPLETED
Conditions: Inflammatory Response|Pain, Postoperative|Nausea, Postoperative|Incontinence|Sexual Behavior
Interventions: DRUG: Dexamethasone phosphate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Bromfenac Ophthalmic Solution in Cataract Surgery
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: bromfenac ophthalmic solution|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Impact on the Therapeutic Alliance of a Short Initial Psychoeducation Programme in Patients With Early Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Psycho-education programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Realizing Opportunities for Self-Supported Improvement (ROSSI)
Status: COMPLETED
Conditions: Domestic Violence|Depression|Quality of Life
Interventions: BEHAVIORAL: Active Comparator: the Community Health Worker -Personalized Support for Progress|BEHAVIORAL: Care as Usual- Social Worker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)
Status: RECRUITING
Conditions: Relapsing Multiple Sclerosis
Interventions: DRUG: Remibrutinib|DRUG: Teriflunomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Examination of the Relationship Between Weight Gain During Pregnancy and Sfrp-5, Netrin-4 and Resistin Concentrations
Status: COMPLETED
Conditions: Excessive Weight Gain During Pregnancy
Interventions: DIAGNOSTIC_TEST: Serum Netrin-4, Resistin and Sfrp-5 level measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Safety, Tolerability and Preliminary Efficacy of AZD5213 in Combination With Pregabalin in Subjects With PDN and Good Pain Reporting Ability
Status: COMPLETED
Conditions: Diabetic Neuropathy, Painful; Diabetic Neuropathies
Interventions: DRUG: AZD5213 + pregabalin|DRUG: Placebo|DRUG: pregabalin capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vasopressor Requirements Depends on Sedation Strategy
Status: COMPLETED
Conditions: Sedative Adverse Reaction|Sedation Complication|Hemodynamic Instability|Agitation on Recovery From Sedation|Respiratory Complication
Interventions: DRUG: Propofol|DRUG: Dexmedetomidine|DRUG: Dexmedetomidine and Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics and Bioequivalence of Rivaroxaban Tablet in Healthy Chinese Volunteers
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Rivaroxaban 20 MG Oral Tablet [Xarelto]|DRUG: Rivaroxaban 20 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation Using Octopus Electrodes for Small Hepatocellular Carcinoma With No-touch Technique
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Radiofrequency Ablation
Interventions: PROCEDURE: RFA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Abdominal Nerve Block on Postoperative Recovery in Patients Undergoing Gastrointestinal Surgery
Status: UNKNOWN
Conditions: Colon Cancer|Rectal Cancer|Gastric Cancer
Interventions: OTHER: Group Abdominal Nerve Block with local anesthetics|OTHER: Group Abdominal Nerve Block with saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Success of Implant Restorations After Immediate or Delayed Implant Placement With/Without Ridge Preservation
Status: NOT_YET_RECRUITING
Conditions: Dental Implant
Interventions: PROCEDURE: Type I Dental implant placement.|PROCEDURE: Type II Dental implant placement.|PROCEDURE: Type III/IV dental implant placement.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Nabilone in the Treatment of Diabetic Peripheral Neuropathic Pain
Status: UNKNOWN
Conditions: Diabetic Neuropathies
Interventions: DRUG: Nabilone, flexible dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Positive Pressure in Morbidly Obese Patients Undergoing Reduction Stomach Surgery
Status: COMPLETED
Conditions: Pulmonary Atelectasis|Respiratory Tract Diseases|Pathological Conditions, Signs and Symptoms
Interventions: PROCEDURE: Positive pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Remifentanil and Dexmedetomidine for Monitored Anaesthesia Care During Vertebroplasty and Kyphoplasty
Status: COMPLETED
Conditions: Fractures, Compression
Interventions: DRUG: Remifentanil|DRUG: Dexmedetomidine|DRUG: midazolam|DRUG: propofol|DRUG: ephedrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Comparison Between HepaSphere Drug-eluting Bead Transarterial Chemoembolization Combined With Hepatic Arterial Infusion Chemotherapy in Advanced Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Advanced Hepatocellular Carcinoma (HCC)
Interventions: PROCEDURE: DEB-TACE plus HAIC or HAIC alone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: AllogeneiC Expanded Human MSC Therapy in Patients Recovering From COVID-19 Acute Respiratory Distress Trial
Status: NOT_YET_RECRUITING
Conditions: ARDS, Human
Interventions: BIOLOGICAL: intravenous delivery of allogeneic bone marrow-derived MSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TREATMENT OF POST-TRAUMATIC STRESS DISORDER USING AUGMENTED IMAGINATION EXPOSURE PSYCHOTHERAPY WITH VOCAL FEEDBACK: AN ACCEPTABILITY STUDY
Status: NOT_YET_RECRUITING
Conditions: Post-traumatic Stress Disorder
Interventions: BEHAVIORAL: Imaginary exposure therapy augmented by vocal feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Afatinib Window Study in Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Carcinoma, Squamous Cell of Head and Neck
Interventions: DRUG: Afatinib|OTHER: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Platform Study to Evaluate Investigational Therapies in Chronic Hepatitis B Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatitis B, Chronic
Interventions: DRUG: VIR-3434|DRUG: VIR-2218|DRUG: TDF|DRUG: PEG-IFNα
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptive Training Exercise Programs for Improving Cardiorespiratory Fitness After Breast Cancer Treatment, The ACTIVATE Trial
Status: COMPLETED
Conditions: Breast Cancer|Invasive Breast Carcinoma
Interventions: OTHER: Aerobic Exercise Intervention|OTHER: Resistance Exercise Intervention|OTHER: Exercise Intervention: Digital copies and outline of sessions|OTHER: Questionnaire Administration|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Therapeutic Ultrasound on Soft Tissue: An Experimentally-induced Skin Model
Status: COMPLETED
Conditions: Inflammation
Interventions: DEVICE: Active Therapeutic Ultrasound|DEVICE: Non-active Therapeutic Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tofacitinib Ointment For Atopic Dermatitis (Atopic Eczema)
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: Tofacitinib ointment 20mg/g|DRUG: Placebo ointment (Vehicle)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Lidocaine and Dexamethasone Combination on Postoperative Sore Throat, Cough and Hoarseness.
Status: COMPLETED
Conditions: Postoperative Sore Throat, Cough, Hoarseness
Interventions: DRUG: LD: Lidocaine and dexamethasone|DRUG: L:Lidocaine|DRUG: D: Dexamethasone|DRUG: N: Normal saline (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Repeat Ivermectin Mass Drug Administrations for Control of Malaria: a Pilot Safety and Efficacy Study
Status: COMPLETED
Conditions: Malaria|Lymphatic Filariasis
Interventions: DRUG: Ivermectin|DRUG: Albendazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Neoadjuvant Endocrine Therapy Compared to Chemotherapy in Breast Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Female Breast Cancer
Interventions: DRUG: Hormonal Antineoplastics|DRUG: Chemotherapy drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating the Effect of Mucinex 1200mg on Mucociliary and Cough Clearance During an Acute Respiratory Infection
Status: COMPLETED
Conditions: Acute Respiratory Infection
Interventions: DRUG: Mucinex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy (CBT) for Adherence and Depression in Type 1 Diabetes
Status: COMPLETED
Conditions: Depression|Type 1 Diabetes
Interventions: BEHAVIORAL: Cognitive behavioral therapy for adherence and depression
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultherapy® for the Treatment of Erythematotelangiectatic Rosacea
Status: COMPLETED
Conditions: Erythematotelangiectatic Rosacea|Rosacea
Interventions: DEVICE: Ulthera System Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Immune Response, Safety and the Occurrence of Respiratory Syncytial Virus (RSV)-Associated Respiratory Tract Illness After Administration of RSV OA Vaccine in Adults 60 Years and Older
Status: RECRUITING
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSVPreF3 OA investigational vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treated Dentine Matrix and Platelet Rich Fibrin in Induction of Root Formation of Non-Vital Immature Permanent Teeth
Status: COMPLETED
Conditions: Regenerative Endodontic Procedures|Necrotic Pulp
Interventions: OTHER: Regenerative endodontic procedues
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Dose Ranging Study of Spinosad Creme Rinse
Status: COMPLETED
Conditions: Pediculosis Capitis|Head Lice
Interventions: DRUG: Spinosad Creme Rinse - Vehicle Control|DRUG: Spinosad Creme Rinse|DRUG: Spinosad Creme Rinse|DRUG: Spinosad Creme Rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Effect of Montelukast Sodium as an Episode Modifier in the Treatment of Infrequent Episodic Asthma in Children (0476-165)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: MK0476; montelukast sodium|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT