pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison Between the Effect of Ultrasound Debridement and Conventional Treatment in Diabetic Foot Ulcers (DFU).
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer
Interventions: PROCEDURE: Ultrasound Debridement|PROCEDURE: Conventional Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Jin-shui Huan-xian Granule in the Treatment of IPF
Status: UNKNOWN
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Jin-shui Huan-xian granule|DRUG: Jin-shui Huan-xian granule placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety, Tolerability and Efficacy of NP-101 in Treating High Risk Participants Who Are Covid-19 Positive.
Status: RECRUITING
Conditions: COVID-19
Interventions: DRUG: NP-101|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tenofovir in Pregnancy to Prevent Mother to Child Transmission of Hepatitis B.
Status: COMPLETED
Conditions: Hepatitis B|Tenofovir|Pregnancy
Interventions: DRUG: Tenofovir Disoproxil Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease
Status: RECRUITING
Conditions: Asthma|COPD|Interstitial Lung Disease|Cystic Fibrosis|Pulmonary Hypertension|Pulmonary Infection|Other Lung Disease
Interventions: DRUG: Hyperpolarized Xe129
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Acetylcholine Iontophoresis As A New Challenge With Type 2 Diabetic Peripheral Neuropathy: A Possible New Therapy
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus|Peripheral Neuropathy
Interventions: PROCEDURE: Acetylcholine Iontophoresis|PROCEDURE: Shame Acetylcholine Iontophoresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Injecting Botulinum Toxin A Underneath the Skin to Treat Spinal Cord Pain in Patients With Spinal Cord Injury
Status: TERMINATED
Conditions: Neuropathic Back Pain|Spinal Cord Injury
Interventions: DRUG: Botulinum Toxin A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Angle Closure Glaucoma and Aqueous Dynamics
Status: COMPLETED
Conditions: Primary Angle Closure
Interventions: PROCEDURE: Phacoemulsification (Acrylic Foldable Intraocular Lens (Acrysoft)), (Healon5)|PROCEDURE: Phacoemulsification and goniosynechialysis (Acrylic Foldable Intraocular Lens (Acrysoft)), (Healon5)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Intrapartum Epidural Fixation Devices: A Randomised Controlled Trial
Status: COMPLETED
Conditions: Labour|Childbirth
Interventions: DEVICE: Tegaderm TM|DEVICE: Lock-it Plus|DEVICE: Epifix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Bupivacain Local Infiltration for the Management of Pain During Cesarean Section
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: Bupivacain|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Combined With Cisplatin and Etoposide or Carboplatin and Pemetrexed in Treating Patients With Metastatic Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: carboplatin|DRUG: cisplatin|DRUG: etoposide|DRUG: pemetrexed disodium|DRUG: sorafenib tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Test and Reference 120 mg Etoricoxib Film-coated Tablets in Healthy Volunteers
Status: COMPLETED
Conditions: Bioequivalence|Healthy Subjects
Interventions: DRUG: Exib 120 mg etoricoxib film-coated tablets|DRUG: Arcoxia® 120 mg etoricoxib film-coated tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Preoperative Chemoradiotherapy and Transanal Endoscopic Microsurgery Versus Total Mesorectal Excision in T2-T3s N0, M0 Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DRUG: Capecitabine (Xeloda)|RADIATION: 50.4 Gy|PROCEDURE: Transanal Endoscopic Microsurgery|PROCEDURE: Total Mesorectal Excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tumor Treating Fields (TTFields, 150kHz) Concomitant With Sorafenib For Advanced Hepatocellular Carcinoma (HCC) (HEPANOVA)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: NovoTTF-100L(P) device|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide and Obinutuzumab for Previously Untreated CLL
Status: WITHDRAWN
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Lenalidomide|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 10-year Follow-up of Clinical Outcome After Antipsychotic Treatment Discontinuation in Psychosis Individuals
Status: UNKNOWN
Conditions: Schizophrenia|Schizophrenia Relapse|Schizophrenia Spectrum and Other Psychotic Disorders
Interventions: OTHER: Antipsychotic treatment discontinuation|OTHER: Maintenance treatment discontinuation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety and Efficacy of ORADUR®-Methylphenidate in Children and Adolescents With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Placebo First, then ORADUR®|DRUG: ORADUR® First, then Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Randomized Controlled Study of Morphine and Nortriptyline in the Management of Postherpetic Neuralgia
Status: COMPLETED
Conditions: Pain|Herpes Zoster
Interventions: DRUG: desipramine|DRUG: methadone|DRUG: morphine|DRUG: nortriptyline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of a Protein Pulse-Feeding Pattern in Elderly Patients
Status: COMPLETED
Conditions: Protein-Energy Malnutrition
Interventions: DIETARY_SUPPLEMENT: Protein pulse-feeding|DIETARY_SUPPLEMENT: Spread diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Flour Compositions in a Carbohydrate-based Food on Rate of Exogenous Glucose Appearance in Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Carbohydrate based food mix 1|DIETARY_SUPPLEMENT: Carbohydrate based food mix 2|DIETARY_SUPPLEMENT: Control carbohydrate based food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Peginterferon α-2b Combined CO2 Laser in Condylomata Acuminata
Status: NOT_YET_RECRUITING
Conditions: Condylomata Acuminata
Interventions: DRUG: Peginterferon α-2b injection|DRUG: Peginterferon α-2b injection|OTHER: CO2 laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing the Incidence of Nevirapine Resistance Mutations in Pregnant HIV Infected Women Who Receive Anti-HIV Drugs Prior to and After Giving Birth
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Didanosine, enteric-coated|DRUG: Lopinavir/ritonavir|DRUG: Nevirapine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Radiation Therapy, Paclitaxel Poliglumex, and Carboplatin in Stage III Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Paclitaxel poliglumex|DRUG: Carboplatin|RADIATION: External beam radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Immunogenicity of a Plant-Made H1 VLP Influenza Vaccine in Adults
Status: COMPLETED
Conditions: Flu
Interventions: BIOLOGICAL: Dose given at Day 0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Axitinib +/- Pembrolizumab in First Line Treatment of mPRCC
Status: RECRUITING
Conditions: Papillary Renal Cell Carcinoma Type 2
Interventions: DRUG: Axitinib Oral Tablet [Inlyta]|DRUG: Pembrolizumab Injection [Keytruda]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Near-Infrared Image Guided Surgical Resection With Indocyanine Green in Treating Patients With Head and Neck Cancer
Status: WITHDRAWN
Conditions: Head and Neck Carcinoma
Interventions: PROCEDURE: Image-Guided Surgery|DRUG: Indocyanine Green Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine, Ascorbate, Radiation Therapy for Pancreatic Cancer, Phase I
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Neoplasms
Interventions: DRUG: Ascorbate|DRUG: Gemcitabine|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantification of Posterior Capsule Opacification in Pediatric Cataract
Status: COMPLETED
Conditions: Posterior Capsule Opacification
Interventions: PROCEDURE: Cataract Surgery|DEVICE: Alcon AcrySof SA60AT|DEVICE: Bausch Lomb AkreosA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Artificial Intelligence to Improve Cardiometabolic Risk Evaluation Using CT Scans
Status: NOT_YET_RECRUITING
Conditions: Pre-diabetes|Diabetes Mellitus
Interventions: DIAGNOSTIC_TEST: Oral Glucose Tolerance Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Two FiO2 (1 or 0.5) for Tracheal Extubation in Post-anesthesia Care Unit
Status: COMPLETED
Conditions: Anesthesia|Atelectasis|Postoperative Complications|Hypoxemia|Hyperoxia
Interventions: OTHER: FiO2 0.5|OTHER: FiO2 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sensory Perceptual Training on Activities of Daily Living and Hand Functions
Status: NOT_YET_RECRUITING
Conditions: Cerebral Palsy, Spastic
Interventions: OTHER: physical therapy excersies|OTHER: sensory perceptual motor exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Multiple Rising Oral Doses of BI 224436 in Healthy Male Volunteers.
Status: WITHDRAWN
Conditions: HIV Infections|Healthy
Interventions: DRUG: BI 224436|DRUG: BI 224436|DRUG: BI 224436|DRUG: BI 224436|DRUG: BI 224436|DRUG: BI 224436|DRUG: BI 224436|DRUG: BI 224436|DRUG: BI 224436|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Bevacizumab and Sorafenib Combined With Low Dose Cyclophosphamide in Patients With Refractory Solid Tumors and Leukemia
Status: COMPLETED
Conditions: Refractory Solid Tumors|Leukemia
Interventions: DRUG: Bevacizumab|DRUG: Sorafenib|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QUILT-3.052: NANT Non-Hodgkin Lymphoma (NHL) Vaccine: Combination Immunotherapy in Subjects With Relapsed CD20-positive NHL
Status: WITHDRAWN
Conditions: Non Hodgkin Lymphoma
Interventions: BIOLOGICAL: avelumab|BIOLOGICAL: bevacizumab|DRUG: capecitabine|DRUG: cyclophosphamide|DRUG: 5-Fluorouracil (5-FU)|DRUG: leucovorin|DRUG: nab-paclitaxel|DRUG: Lovaza|DRUG: Oxaliplatin|DRUG: rituximab|RADIATION: Stereotactic Body Radiation Therapy|BIOLOGICAL: ALT-803|BIOLOGICAL: ETBX-061|BIOLOGICAL: haNK
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemoprevention With Tamoxifen in Pre-Invasive Pancreas Mucinous Cystic Neoplasms Not Undergoing Immediate Resection
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cyst|Pancreatic Mucinous Cystic Neoplasm
Interventions: DRUG: Tamoxifen 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Stellate Ganglion Block for PTSD
Status: RECRUITING
Conditions: Post-traumatic Stress Disorder
Interventions: PROCEDURE: Stellate Ganglion Block|PROCEDURE: Sham Stellate Ganglion Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Safety and Efficacy of CAR-T Cells Targeting CD123 in Patients With Acute Myelocytic Leukemia
Status: UNKNOWN
Conditions: Acute Myelocytic Leukemia
Interventions: BIOLOGICAL: CD123 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Luteal Support for Frozen-Thawed Embryo Transfer - A Prospective Study
Status: UNKNOWN
Conditions: Embryo Transfer|Luteal Support
Interventions: DRUG: Choriogonadotropin alfa|DRUG: Triptorelin acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of Black Bean Pasta Consumption on Biomarkers in Young Adults
Status: COMPLETED
Conditions: Glucose, High Blood
Interventions: DIETARY_SUPPLEMENT: White bread|DIETARY_SUPPLEMENT: Black beans whole boiled|DIETARY_SUPPLEMENT: Knife Mill pasta|DIETARY_SUPPLEMENT: Combo Flour Pasta|DIETARY_SUPPLEMENT: Cyclone Flour Pasta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: R-MVST Cells for Treatment of Viral Infections
Status: RECRUITING
Conditions: Epstein-Barr Virus Infections|Cytomegalovirus Infections|Adenovirus|BK Virus Infection
Interventions: DRUG: Rapidly generated virus specific T (R-MVST) cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aromasin Vs Arimidex Study As Initial Hormonal Therapy In Postmenopausal Women With Advanced/Recurrent Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: exemestane|DRUG: anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Lurbinectedin in Combination With Doxorubicin Versus Doxorubicin Alone as First-line Treatment in Participants With Metastatic Leiomyosarcoma
Status: RECRUITING
Conditions: Leiomyosarcoma
Interventions: DRUG: Lurbinectedin|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Methods of Bladder Tumor Extraction and Local Recurrence Rate
Status: UNKNOWN
Conditions: Bladder Cancer
Interventions: PROCEDURE: en bloc resection, morcellation|PROCEDURE: piecemeal resection, tissue removal by loop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dermacyd PH_DETINLYN (Lactic Acid) Sweet Flower - Photo Evaluation.
Status: COMPLETED
Conditions: Hygiene
Interventions: DRUG: Dermacyd PH_DETINLYN (Lactic Acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Robotic Surgical Management of Endometriosis: Excision Versus Ablation
Status: COMPLETED
Conditions: Endometriosis
Interventions: PROCEDURE: Robotic ablation|PROCEDURE: Robotic excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Bacterial Vaginosis Prior to Active Labor and Infectious Morbidity
Status: TERMINATED
Conditions: Bacterial Vaginoses
Interventions: DRUG: Metronidazole Oral|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Aripiprazole to Treat Children and Adolescents With Autism
Status: COMPLETED
Conditions: Autistic Disorder|Asperger Syndrome|Autism Spectrum Disorder
Interventions: DRUG: aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluid Volume-hypotension Association in Cesarean Under Neuraxial Anesthesia
Status: COMPLETED
Conditions: Cesarean Section
Interventions: DRUG: Ringer's Lactate|DRUG: Six percent hydroxyethyl starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Trial of A COVID-19 Vaccine of Adenovirus Vector in Adults 18 Years Old and Above
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Patient-ventilator Interactions in Long Term Non-invasive Ventilation: Influence of Back-up Frequency
Status: COMPLETED
Conditions: Obesity|Non Invasive Ventilation
Interventions: DEVICE: Adjustment of back-up respiratory rate on bi-level ventilator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Tolerability and Pharmacokinetics of Jiashen Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Jiashen Tablets|DRUG: Jiashen Tablets|DRUG: Jiashen Tablets|DRUG: Jiashen Tablets|DRUG: Jiashen Tablets|DRUG: Jiashen Tablets|DRUG: Jiashen Tablets Placebo|DRUG: Jiashen Tablets Placebo|DRUG: Jiashen Tablets Placebo|DRUG: Jiashen Tablets Placebo|DRUG: Jiashen Tablets Placebo|DRUG: Jiashen Tablets Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention Study - Effectiveness of Smartphone Delivered Interval Walking Training to Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Interval walking training|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mirtazapine for Acute and Chronic Post Mastectomy Pain
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Mirtazapine 30 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Creatine Supplementation and Resistance Training to Preserve Muscle Mass and Attenuate Cancer Progression
Status: RECRUITING
Conditions: Metastatic Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: creatine monohydrate|OTHER: Placebo|BEHAVIORAL: Home-based, telehealth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Surgery and Functionality in Older Adults
Status: ENROLLING_BY_INVITATION
Conditions: Fear|Movement Disorder, Functional|Kinesiophobia|Surgery
Interventions: OTHER: therapatic Foot massaje (sweden technic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Pharmacokinetic of Recombinant Human Coagulation Factor VIII ，Fc Fusion Protein for Injection
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: ADVATE|DRUG: FRSW107
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Cervical Stiffness in the Second Trimester Predict Preterm Birth in High-Risk Singleton Pregnancies?
Status: RECRUITING
Conditions: Preterm Birth
Interventions: DEVICE: Cervical stiffness assessment|OTHER: Cervical length measurement|OTHER: Fetal fibronectin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clavicle Splint for Pain Reduction After Posterior Cervicothoracic Surgery
Status: COMPLETED
Conditions: Posterior Cervical Surgery|Posterior Cervical Fusion|Posterior Cervical Laminectomy|Posterior Cervical Laminoplasty
Interventions: DEVICE: Clavicle Brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age
Status: RECRUITING
Conditions: Premature Birth|Asthma in Children|Sleep-Disordered Breathing|Neurodevelopmental Disorders
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Compliance to Oral Nutritional Supplements (ONS) in Undernourished Frail Older Adults Living at Home.
Status: COMPLETED
Conditions: Frail Elderly
Interventions: DIETARY_SUPPLEMENT: Fortimel® Protein supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of a Multicomponent and Interdisciplinary Intervention on the Care Ability and Burden of Family Caregivers of People With Chronic Cardiocerebrovascular Diseases
Status: UNKNOWN
Conditions: Caregivers|Burnout, Psychological
Interventions: BEHAVIORAL: Intervention group: Educational Intervention "KARER"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Valproic Acid in Childhood Progressive Brain Tumors
Status: WITHDRAWN
Conditions: Pediatric Brain Tumor|Glioma|Anaplastic Astrocytoma|Medulloblastoma|Glioblastoma
Interventions: DRUG: Valproic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Escalating Doses of NRL001 Given in Slow-release Rectal Suppositories of Different Weights
Status: COMPLETED
Conditions: Incontinence
Interventions: DRUG: NRL001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: bicalutamide|DRUG: flutamide|DRUG: LHRH agonist (antagonist) therapy|RADIATION: Dose-Escalated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pregablin for Anxiety-comorbidity in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Anxiety-comorbidity to Schizophrenia
Interventions: DRUG: Pregabalin|DRUG: Pregabalin Placebo Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serratus Anterior Plane Block Combined With Transversus Thoracic Muscle Plane Block Versus Conventional Local Anesthetic Infiltration for SICD Implantation: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Serratus Anterior Plane Block|Transversus Thoracis Plane Block|Subcutaneous ICD
Interventions: PROCEDURE: Combined serratus anterior plane block and transversus thoracis plane block|PROCEDURE: Standard local infiltration technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Roxadustat for the Treatment of Anemia in Participants With Chronic Kidney Disease and Not Receiving Dialysis
Status: COMPLETED
Conditions: CKD Anemia
Interventions: DRUG: Roxadustat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Melatonin on Early Signs of Hypertension in Teenagers With Diabetes Mellitus Type 1
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1|Hypertension
Interventions: DRUG: Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Adaptive Radiotherapy Based on PET/CT and IMRT for Locally Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: Lung Neoplasms
Interventions: OTHER: Radiotherapy dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VITRO-Trial. B Vitamins and the Secondary Prevention of Venous Thrombosis
Status: COMPLETED
Conditions: Deep-Vein Thrombosis|Pulmonary Embolism
Interventions: DRUG: 5 mg folic acid, 50 mg pyridoxine and 0.4 mg cyanocobalamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Impact of C-arm CT in Decreased Renal Function Undergoing TACE for Tx of Hepato-Cellular Carcinoma
Status: TERMINATED
Conditions: Kidney (Renal Cell) Cancer
Interventions: DEVICE: dTA/dBA C-arm fluoroscopy system with Dyna CT|PROCEDURE: DSA arteriogram- hepatic arteries|PROCEDURE: CO2 aortogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 3 Study to Evaluate the Immunogenicity and Safety of Walvax's PCV13-TT as Compared to Pfizer's PCV13
Status: ACTIVE_NOT_RECRUITING
Conditions: Pneumococcal Disease, Invasive
Interventions: BIOLOGICAL: Walvax PCV13-TT|BIOLOGICAL: Pfizer PCV13
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: OPHTHALMOLOGIC EVALUATION OF RADIATION-RELATED OPTIC NEUROPATHY FOLLOWING IMAGE GUIDED INTENSITY-MODULATED RADIATION THERAPY (IMRT) FOR NASOPHARYNGEAL CARCİNOMA
Status: UNKNOWN
Conditions: The Aim of Our Study is to Prospectively Evaluate the Optic Neuropathy in Nasopharynx Cancer Patients
Interventions: RADIATION: IMRT(IMAGE GUIDED INTENSITY-MODULATED RADIATION THERAPY )
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: One-stop-shop Study for Treatment of Basal Cell Carcinoma Using Reflectance Confocal Microscopy
Status: COMPLETED
Conditions: Carcinoma, Basal Cell
Interventions: DEVICE: Reflectance confocal microscopy|PROCEDURE: Punch biopsy|PROCEDURE: Surgical excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Escalation Study of Intraperitoneal (IP) Cisplatin, IV/IP Paclitaxel, IV Bevacizumab, and Oral Olaparib for Newly Diagnosed Ovarian, Primary Peritoneal, and Fallopian Tube Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Primary Peritoneal Cancer|Fallopian Tube Cancer
Interventions: DRUG: Paclitaxel,|DRUG: Bevacizumab|DRUG: Cisplatin|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Jinfukang Oral Liquid Combined With Chemotherapy for Treating Driver Gene-negative Advanced NSCLC
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Jinfukang oral liquid|DRUG: Platinum-based doublet chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ICTUS Study: International Citicoline Trial on Acute Stroke
Status: TERMINATED
Conditions: Acute Stroke|Cerebral Infarction
Interventions: DRUG: Citicoline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy Associated With Full-mouth Ultrasonic Debridement in the Treatment of Severe Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: OTHER: photodynamic therapy and periodontal debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognition, Flavonoids, Exercise, Gut Microbiome
Status: NOT_YET_RECRUITING
Conditions: Cognitive Decline, Mild
Interventions: DIETARY_SUPPLEMENT: Blueberry|BEHAVIORAL: Walking|DIETARY_SUPPLEMENT: Placebo|BEHAVIORAL: Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transplant-Related Mortality in Patients Undergoing a Peripheral Blood Stem Cell Transplantation or an Umbilical Cord Blood Transplantation
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Myelodysplastic Syndrome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Efficacy and Safety Study of Cisapride for Improving Symptoms Associated With Gastroparesis in Patients With Diabetes Mellitus
Status: TERMINATED
Conditions: Gastroparesis|Diabetes Mellitus
Interventions: DRUG: Cisapride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DIstal vs Proximal Radial Artery Access for Cath
Status: COMPLETED
Conditions: Coronary Angiography|Coronary Angioplasty
Interventions: PROCEDURE: Distal radial artery access|PROCEDURE: Proximal radial artery surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Crossover Study Comparing Ondansetron Orally Dissolving Film Strip (ODFS) With Zofran Orally Disintegrating Tablets
Status: COMPLETED
Conditions: Nausea and Vomiting, Postoperative|Nausea With Vomiting Chemotherapy-Induced
Interventions: DRUG: Ondansetron (ODFS)|DRUG: Zofran (ODT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Osseodensification Versus Osteotome Internal Sinus Lifting in Delayed Implant Placement
Status: RECRUITING
Conditions: Maxillary Sinus Floor Augmentation
Interventions: PROCEDURE: Osseodensification Internal Sinus Lift|PROCEDURE: Osteotome Internal Sinus Lift
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of High-intensity Interval Training on Cardiac Function and Regulation of Glycemic Control in Diabetic Cardiomyopathy
Status: COMPLETED
Conditions: Diabetic Cardiomyopathies|Type2 Diabetes
Interventions: OTHER: high-intensity interval exercise training (HIIT)|OTHER: moderate-intensity exercise training (MIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tipifarnib in Treating Patients With Myelofibrosis and Myeloid Metaplasia
Status: COMPLETED
Conditions: Essential Thrombocythemia|Polycythemia Vera|Primary Myelofibrosis
Interventions: DRUG: tipifarnib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Release and Ischemic Pressure of Trigger Points on Neck Pain. A Crossover, Controlled and Randomized Trial.
Status: UNKNOWN
Conditions: Myofascial Trigger Point Pain|Myofascial Pain|Myofascial Pain Syndrome|Neck Pain
Interventions: OTHER: Pressure Release technique|OTHER: Ischemic pressure technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Sports Injury Prevention Program to Reduce Subsequent Injuries After Concussion
Status: COMPLETED
Conditions: Brain Concussion|Musculoskeletal Injury|Locomotion|Postural Balance
Interventions: BEHAVIORAL: Neuromuscular training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Clinical Trial of Repeated Doses of Macimorelin to Assess Safety and Efficacy in Patients With Cancer Cachexia
Status: COMPLETED
Conditions: Cancer Cachexia
Interventions: DRUG: Macimorelin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Mass Balance, Pharmacokinetics, Metabolite Profile, and Metabolite Identification of BIIB122/DNL151 in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: [14C] BIIB122 ([14C] DNL151)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Diagnostics Of Syncope Events Using Intelligent Telemetric Solutions.
Status: UNKNOWN
Conditions: Cardiac Arrhythmia|Cardiogenic Syncope
Interventions: DEVICE: repeated 24 hours ECG Holter monitoring|DEVICE: Telemetric ECG monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Previously Treated Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-Small Cell Lung Carcinoma|Stage IV Non-Small Cell Lung Cancer
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel Albumin-Stabilized Nanoparticle Formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Safety Of Patients Switching To ReFacto AF In Usual Care Settings
Status: TERMINATED
Conditions: Hemophilia A
Interventions: DRUG: moroctocog alfa (AF-CC) (ReFacto AF)|PROCEDURE: Laboratory tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Alprazolam on the Success of Inferior Alveolar Nerve (IAN) Block
Status: COMPLETED
Conditions: Inferior Alveolar Nerve Block Failure
Interventions: DRUG: Alprazolam|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The HIIT Cognition Study
Status: COMPLETED
Conditions: High Intensity Interval Training|Overweight and Obesity|Metabolic Disease|Cognition
Interventions: BEHAVIORAL: HIIT Exercise Intervention|BEHAVIORAL: Stretching Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Generating Health Evidence From Dietary Supplementation With a Micro-vegetable Blend
Status: RECRUITING
Conditions: Inflammation
Interventions: DIETARY_SUPPLEMENT: Micro-vegetable blend|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Efficacy and Safety of Budesonide/Albuterol Metered-dose Inhaler (BDA MDI/PT027) in Adults and Children 4 Years of Age or Older With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: COMBINATION_PRODUCT: Budesonide/albuterol sulfate metered-dose inhaler 160/180 μg|COMBINATION_PRODUCT: Budesonide/albuterol sulfate metered-dose inhaler 80/180 μg|DRUG: Albuterol sulfate metered-dose inhaler 180 μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Drug Interactions of Saxagliptin With Sildenafil in Healthy Volunteers
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Erectile Dysfunction With Diabetes Mellitus|Drug Interaction
Interventions: DRUG: Saxagliptin 5mg|DRUG: Sildenafil 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study Evaluate the PK Profile of Dalbavancin in Infants and Neonates Patients With Known or Suspected Bacterial Infection
Status: TERMINATED
Conditions: Bacterial Infections
Interventions: DRUG: Dalbavancin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Theta Burst Transcranial Magnetic Stimulation as Treatment for Auditory Verbal Hallucinations
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorders
Interventions: OTHER: Theta Burst Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical And Anatomic Study Of An Ultrasound-Guided Superior Trunk Of The Brachial Plexus
Status: UNKNOWN
Conditions: Brachial Plexus Block|Shoulder Surgery
Interventions: PROCEDURE: Bupivacaine - Superior Trunk Block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Compare the Efficacy of Endoscopic Ultrasound Assisted Endoscopic Glue Injection and Conventional Endoscopic Injection Therapy for Prevention of Gastric Variceal Rebleed
Status: WITHDRAWN
Conditions: Bleeding Gastric Varices
Interventions: PROCEDURE: Endoscopic Ultrasound assisted endoscopic glue injection|PROCEDURE: Standard Endotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Manipulation of the Gut Microbiome by a Standardized Preoperative Diet to Prevent Colorectal Cancer Recurrence and Metastasis Following Surgery
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: DIETARY_SUPPLEMENT: Plant-Based Meals
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Continuous Positive Airway Pressure on Peripheral Oxygen Saturation, Work of Breathing, and Exercise Tolerance at Altitude
Status: ENROLLING_BY_INVITATION
Conditions: Hypoxemia|Altitude Hypoxia
Interventions: DEVICE: Continuous positive airway pressure|DEVICE: Ambient air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Piloting Home-based Movement-to-Music Among Adolescents With Cerebral Palsy: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: BEHAVIORAL: Movement-to-music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cost Effectiveness of an Intervention in Hospitalized Patients With Disease-related Malnutrition
Status: COMPLETED
Conditions: Pancreatitis, Acute|Crohn Disease|Ulcerative Colitis|Inflammatory Bowel Diseases|Pancreatic Cancer|Esophagus Cancer|Gastric Cancer|Colorectal Cancer
Interventions: DIETARY_SUPPLEMENT: Nutritional dietary intervention|DIETARY_SUPPLEMENT: By demand|DIETARY_SUPPLEMENT: Usual current care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Alglucosidase Alfa in Patients With Pompe Disease
Status: COMPLETED
Conditions: Pompe Disease|Glycogen Storage Disease Type II (GSD II)
Interventions: BIOLOGICAL: alglucosidase alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sleep Apnea Intervention for Cardiovascular Disease Reduction
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: BEHAVIORAL: Conservative Medical Therapy (CMT)|DEVICE: Sham PAP (Sham)|DEVICE: Active PAP with RT Support (Active-Beh)|DEVICE: Active PAP with Behavioral Modification (Active+Beh)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Intermediate Cervical Plexus Block Versus Cutaneous and Thyroid Capsular Blocks
Status: COMPLETED
Conditions: Thyroid Surgery
Interventions: PROCEDURE: Capsule and cutaneous blocks|PROCEDURE: US-intermediate cervical plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate JYP0061 Tablets in Patients With Moderate-to-severe Atopic Dermatitis
Status: NOT_YET_RECRUITING
Conditions: Moderate-to-severe Atopic Dermatitis
Interventions: DRUG: JYP0061 tablet Dose1|DRUG: JYP0061 tablet Dose2|DRUG: JYP0061 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Isoflavones and the Coronary Circulation in Men and Women With Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Genistein|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Malignancy Predictors, Bethesda and TI-RADS Scores Correlated With Final Histopathology in Thyroid Diseases
Status: UNKNOWN
Conditions: Thyroid Carcinoma|Thyroid Papillary Carcinoma|Multinodular Goiter, Adolescent|Solitary Thyroid Nodule|Thyroid Diseases|Multifocal Dysplasia|Aspiration|Thyroid Nodule|Thyroid Cancer, Papillary|Thyroid Neoplasms|Thyroid Goiter
Interventions: PROCEDURE: Total thyroidectomy (TT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BP-C1 in Short-term Treatment of Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer|Unresectable Pancreatic Cancer
Interventions: DRUG: BP-C1|DRUG: BP-C2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vesalio NeVa VS for Symptomatic Cerebral Vasospasm Following aSAH (The VITAL Study)
Status: COMPLETED
Conditions: Cerebral Vasospasm
Interventions: DEVICE: NeVa VS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of 10 and 30 mg Doses of CVL-231 (Emraclidine) in Participants With Schizophrenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: CVL-231 10 mg|DRUG: Required CVL-231 30 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation and Double-blind Study of Veliparib in Combination With Carboplatin and Etoposide in Treatment-naive Extensive Stage Disease Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Veliparib|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT