pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Extension to a Study on the Efficacy and Safety of Vildagliptin in Combination With Insulin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Fluocinolone Acetonide in Diabetic Macular Edema (FAME) Extension Study
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Fluocinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sparking Gut Bacteria Production of Bioactive Xenolipids in Situ
Status: NOT_YET_RECRUITING
Conditions: Dietary Fat Metabolism
Interventions: DIETARY_SUPPLEMENT: Dietary fat positive control|DIETARY_SUPPLEMENT: Dietary fat negative control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Recording of Physiological Data Via an Optical Sensor at the Fingertip Alongside With Double Auscultatory and Pulse Oximetry to Evaluate the Effectiveness of an Optical Blood Pressure Monitoring (OBPM)
Status: COMPLETED
Conditions: Hypertension
Interventions: DEVICE: Investigational device Aktiia G2C|DEVICE: Marketed device used as reference for blood pressure monitoring: double auscultation cuff|DEVICE: Marketed device used as comparative device for blood pressure and pulse rate monitoring: Aktiia Bracelet G2|DEVICE: Marketed device used as comparative device for blood pressure and pulse rate monitoring: oscillometric upper-arm cuff|DEVICE: Marketed device used as comparative device for blood pressure and pulse rate monitoring: oscillometric wrist cuff|DEVICE: Marketed device used as reference for pulse rate monitoring: pulse finger oximeter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of LCP-Tacro™ Once Daily in Stable Renal Transplant Patients Converted From Prograf® Twice Daily
Status: COMPLETED
Conditions: Renal Failure
Interventions: DRUG: LCP-Tacro|DRUG: Prograf
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Efficacy of Different Doses of Bimekizumab in Patients With Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis
Interventions: DRUG: Bimekizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of AEB071 and EVEROLIMUS in Patients With CD79-mutant or ABC Subtype Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: CD79 Mutant or ABC-subtype Diffuse Large B-Cell Lymphoma
Interventions: DRUG: AEB071|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Two Injection Sites of Local Anesthetic for Hand Surgery
Status: COMPLETED
Conditions: Hand Injury|Wrist Injury|Finger Injury
Interventions: PROCEDURE: 0.5% bupivacaine injected in the forearm|PROCEDURE: 20-30ml of 0.5% bupivacaine.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptive Radiotherapy and MRIs Based on Patients With Newly Diagnosed High-Grade Glioma
Status: RECRUITING
Conditions: Glioblastoma|Anaplastic Astrocytoma|Astrocytoma|Anaplastic Oligodendroglioma
Interventions: OTHER: Adaptive Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brinzolamide for the Treatment of Chronic Central Serous Chorioretinopathy
Status: UNKNOWN
Conditions: Central Serous Chorioretinopathy
Interventions: DRUG: Brinzolamide Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 12-Month Study To Evaluate The Safety And Tolerability Of Pregabalin As Add-On Therapy In Pediatric Subjects 1 Month To 16 Years Of Age With Partial Onset Seizures And Pediatric And Adult Subjects 5 To 65 Years Of Age With Primary Generalized Tonic-Clonic Seizures
Status: COMPLETED
Conditions: Epilepsy, Partial Seizures|Epilepsy, Primary Generalized Tonic-Clonic Seizures
Interventions: DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Progesterone Suppression of Wake vs. Sleep Luteinizing Hormone Pulse Frequency in Pubertal Girls With and Without Hyperandrogenism
Status: RECRUITING
Conditions: Puberty|Hyperandrogenism
Interventions: DRUG: Micronized progesterone suspension|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Osteoporosis Among Men Treated With Androgen Deprivation for Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer|Androgen Deprivation Therapy|Osteoporosis
Interventions: PROCEDURE: blood sampling, DXA-scan, bone scintigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of the Impact of a Pediatric Nurse's Consultation on Parental Anxiety During a Febrile Convulsion in Children
Status: RECRUITING
Conditions: Febrile Seizure
Interventions: OTHER: Standard care|OTHER: CONSULFE consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial to Determine the Safety and Efficacy of Fluvastatin in Previous Partial Responders to Pegylated Interferon and Ribivirin in Patients With Genotype 1 Hepatitis C
Status: WITHDRAWN
Conditions: Hepatitis C|Hepatitis C Virus
Interventions: DRUG: Fluvastatin|DRUG: Peginterferon alfa2a|DRUG: ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mental Health Services for Toddlers in Foster Care
Status: COMPLETED
Conditions: Behavior Problems
Interventions: BEHAVIORAL: Attachment and Biobehavioral Catch-up|BEHAVIORAL: Developmental Education for Families
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Investigation of the Effects of Opioid Receptor Blockade on Changes in Self-esteem and Social Attention
Status: COMPLETED
Conditions: Self Esteem
Interventions: DRUG: Naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Patient Satisfaction With Propofol for Out Patient Colonoscopy
Status: COMPLETED
Conditions: Colon Cancer|IBS|Polyps
Interventions: DRUG: Propofol|DRUG: Fentanyl Plus Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preoperative Oral Carbohydrate for Nausea and Vomiting Prevention During Cesarian Section
Status: UNKNOWN
Conditions: Postoperative Nausea and Vomiting
Interventions: DIETARY_SUPPLEMENT: preoperative oral carbohydrate, preOp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Brentuximab Vedotin With Hodgkin Lymphoma (HL) and CD30-expressing Peripheral T-cell Lymphoma (PTCL)
Status: COMPLETED
Conditions: Hodgkin Disease|Peripheral T Cell Lymphoma
Interventions: DRUG: brentuximab vedotin|DRUG: bendamustine|DRUG: dacarbazine|DRUG: nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Electrophysiology, Safety, Tolerability, and Pharmacokinetics of Multiple Doses of SAGE-718 Using Ketamine Challenge in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: SAGE-718|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of a Quick Release Dynamic Muscle-strengthening Program on Dynamic Stabilization of the Cervical Spine
Status: ENROLLING_BY_INVITATION
Conditions: Rugby|Craniocerebral Trauma|Cervical Spine Injury|Stabilization
Interventions: OTHER: isometric contractions|OTHER: stroboscopic glasses|OTHER: Quick Release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Intervention for Postpartum Infections Following Caesarean Section
Status: COMPLETED
Conditions: Surgical Wound Infection|Infection; Cesarean Section|Cesarean Section; Dehiscence|Complications; Cesarean Section|Complications; Cesarean Section, Wound, Dehiscence|Wound; Rupture, Surgery, Cesarean Section
Interventions: DEVICE: Negative Pressure Wound Therapy|OTHER: Standard wound dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-blind Comparison of Scopolamine With Cinnarizin for Prevention of Simulator Sickness
Status: UNKNOWN
Conditions: Simulator Sickness
Interventions: DRUG: scopolamine|DRUG: cinnarizine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Subthalamic Steering for Therapy Optimization in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DEVICE: Omnidirectional Deep Brain Stimulation of STN|DEVICE: Directional Deep Brain Stimulation of STN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HEAT HumiGard Evaluation Study
Status: COMPLETED
Conditions: Laparoscopic Colorectal Surgery
Interventions: DEVICE: HumiGard device|OTHER: Standard care (with sham HumiGard device)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Study Comparing the Safety and Efficacy of ABT-335 and Rosuvastatin Calcium Combination Therapy to Monotherapy in Subjects With Dyslipidemia
Status: COMPLETED
Conditions: Hypercholesterolemia|Dyslipidemia
Interventions: DRUG: ABT-335 and rosuvastatin calcium|DRUG: ABT-335|DRUG: rosuvastatin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5410 in Adult Participants 18 Years of Age and Older
Status: COMPLETED
Conditions: Influenza Immunization
Interventions: BIOLOGICAL: Quadrivalent Influenza mRNA Vaccine MRT5410|BIOLOGICAL: Quadrivalent Recombinant Influenza vaccine RIV4|BIOLOGICAL: Quadrivalent Inactivated Influenza Standard Dose QIV-SD|BIOLOGICAL: Quadrivalent Inactivated Influenza High Dose QIV-HD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: THE LASER-AMI STUDY - Excimer Laser Versus Manual Thrombus Aspiration in Acute Myocardial Infarction
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: DEVICE: Excimer laser|DEVICE: Manual Thrombus Aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Efficacy and Safety of CT-P42 in Comparison With Eylea in Patients With Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema (DME)
Interventions: BIOLOGICAL: CT-P42|BIOLOGICAL: Eylea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gaitbox Validation Study
Status: COMPLETED
Conditions: Validation of Gait Speed Device Against Existing Techniques
Interventions: OTHER: Gaitbox|OTHER: SprintSystem device|OTHER: NIH toolbox 4 meter walk
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ranibizumab DosE Comparison and the Role of LAser in REtinal Vein Occlusions
Status: COMPLETED
Conditions: Retinal Vein Occlusion
Interventions: DRUG: Ranibizumab 0.5mg (monthly)|DRUG: Ranibizumab 2.0mg (monthly)|DRUG: Pro re nata (prn) ranibizumab|PROCEDURE: Pro re nata (prn) Laser photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of a Dose Reduction Strategy Based on Bictegravir/Emtricitabine/Tenofovir Alafenamide in Virologically Suppressed HIV-infected Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections
Interventions: DRUG: Biktarvy 50 mg/200 mg/25 mg film-coated tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Penumbral Based Novel Thrombolytic Therapy in Acute Ischemic Stroke
Status: COMPLETED
Conditions: Cerebral Infarction|Brain Ischemia|Stroke
Interventions: DRUG: Tenecteplase (TNK) (0.25 mg/kg, to maximum of 25mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Treatment With Doxazosin Plus TolterodineSR 2 mg Versus 4mg in Men With an Overactive Bladder (OAB) and Benign Prostatic Hyperplasia (BPH)
Status: COMPLETED
Conditions: Overactive Bladder|Benign Prostatic Hyperplasia
Interventions: DRUG: doxazosin plus tolterodine SR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Cerebral Oximetry in Reducing Postoperative End Organ Dysfunction/Failure After Complex Non-Cardiac Surgery
Status: UNKNOWN
Conditions: Surgery
Interventions: DEVICE: Bilateral NIRS (Masimo, O3TM Regional Oximetry)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy and Safety of Nab-paclitaxel Plus S-1 in First-line Treatment of Advanced Biliary Tract Adenocarcinoma
Status: COMPLETED
Conditions: Biliary Tract Cancer
Interventions: DRUG: Nab-paclitaxel,S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Drug Interaction Between D326, D337, and D013 in Healthy Male Subjects
Status: COMPLETED
Conditions: Dyslipidemias|Hypertension
Interventions: DRUG: D013, D326 and D337|DRUG: D013|DRUG: D326 and D337
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic Screening for Filaggrin Mutation in Atopic Dermatitis and Ichthyosis Vulgaris in the African American Population
Status: COMPLETED
Conditions: Atopic Dermatitis|Ichthyosis Vulgaris
Interventions: GENETIC: Buccal Swab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: PD-L1 Expression in Cancer (PECan Study).
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|Melanoma
Interventions: DIAGNOSTIC_TEST: [99mTc]-NM-01 SPECT/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of CSP01 on Chronic Idiopathic Constipation and Irritable Bowel Syndrome With Constipation
Status: COMPLETED
Conditions: Constipation|Chronic Idiopathic Constipation|Irritable Bowel Syndrome With Constipation
Interventions: DEVICE: CSP01|DEVICE: Carboxymethylcellulose (CMC)|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Auricular Acupuncture in Substance Abuse: Effects on Anxiety, Sleep, Drug Use.
Status: COMPLETED
Conditions: Substance Abuse|Anxiety|Sleep
Interventions: DEVICE: NADA Acupuncture|DEVICE: LP acupuncture|BEHAVIORAL: Relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Soft Tissue Volume Gain and Stability Comparing Palate and Tuberosity
Status: UNKNOWN
Conditions: Tooth Loss|Recession, Gingival
Interventions: PROCEDURE: Soft tissue augmentation palate|PROCEDURE: Soft tissue augmentation tuberosity|DEVICE: Intraoral optical scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Comparison of Different Root Coverage Techniques Using the Anatomical Recession Area Approach
Status: NOT_YET_RECRUITING
Conditions: Gingival Recession
Interventions: PROCEDURE: Coronally Positioned Flap with Connective Tissue Graft|PROCEDURE: Modified Coronally Advanced Tunnel with Connective Tissue Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of a Human Anti-Intercellular Adhesion Molecule-1 Monoclonal Antibody, in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: BI-505
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of the SNS-Based Feeding on Transition to Exclusive Breastfeeding in Preterm Infants
Status: COMPLETED
Conditions: Breastfeeding|Preterm Infant|Sucking Behavior
Interventions: DEVICE: MEDELA Supplemental nursing system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neo-adjuvant Gemcitabine, Epirubicin, ABI-007 (GEA) in Locally Advanced or Inflammatory Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Gemcitabine|DRUG: Epirubicin|DRUG: Albumin-bound Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolites Profiling Reveals Nutrient Processing Patterns Upon Dietary Loading
Status: NOT_YET_RECRUITING
Conditions: Metabolism Disorder|Nutrition
Interventions: OTHER: Macronutrients|OTHER: Mixed meal tolerance test (MMTT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of aPDT in Reducing Pain and Swelling Following Molar Extraction Surgery- Blinded Randomized Controlled Clinical Trial
Status: COMPLETED
Conditions: Tooth Extraction Status Nos
Interventions: PROCEDURE: Molar extraction - Control Group|PROCEDURE: aPDT + Molar Extraction - Test Group 1|PROCEDURE: Infrared + Molar Extraction - Test Group 2|PROCEDURE: aPDT + Infrared + Molar Extraction - Test Group 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: What Difficulties do Children and Adolescents Experience in Everyday Activities After a Traumatic Event? Focus Groups and Delphi Survey for the Development of a Questionnaire on PTSD-related Functional Impairment
Status: RECRUITING
Conditions: PTSD|Functioning, Psychosocial
Interventions: OTHER: Focus groups and Delphi Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CD34 Selected Allogeneic HCT w/ Myeloablative Conditioning Plus CD8+ Memory TCell Infusion in MDS, AL and CML
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Myelodysplastic Syndromes|Acute Leukemia|Chronic Myeloid Leukemia
Interventions: DRUG: CD8+ Memory T Cell Infusion|DRUG: Thiotepa|DRUG: Fludarabine|RADIATION: Hyperfractionated TBI|DRUG: Busulfan|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anakinra for the Reduction of CAR-T Toxicity in Patients With Relapsed or Refractory Large B-cell Lymphoma
Status: COMPLETED
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent High Grade B-Cell Lymphoma|Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma|Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory High Grade B-Cell Lymphoma|Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma|Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma
Interventions: BIOLOGICAL: Anakinra|BIOLOGICAL: Axicabtagene Ciloleucel|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3, Open-label Clinical Trial of EB-101 for the Treatment of Recessive Dystrophic Epidermolysis Bullosa (RDEB)
Status: COMPLETED
Conditions: Epidermolysis Bullosa|Recessive Dystrophic Epidermolysis Bullosa
Interventions: BIOLOGICAL: EB-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Study of Children With a Chronic Cough and the Impact of Gastroesophageal Reflux
Status: WITHDRAWN
Conditions: Cough|Gastroesophageal Reflux
Interventions: DRUG: Proton Pump Inhibitor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: "Tailored" Bilio-Pancreatic Limb Length and Weight Loss After Mini-Gastric Bypass
Status: COMPLETED
Conditions: Obesity, Morbid|Weight Loss|Bariatric Surgery Candidate|Power
Interventions: PROCEDURE: Mini-Gastric Bypass - Original Technique
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quad Resection (Hot Snare vs Cold Snare vs Hot EMR vs Cold EMR)
Status: COMPLETED
Conditions: Colon Cancer|Colon Polyp|Colon Adenoma
Interventions: PROCEDURE: Cold Snare|PROCEDURE: Hot Snare|PROCEDURE: Cold EMR|PROCEDURE: Hot EMR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prochlorperazine Versus Prochlorperazine & Ketorolac in Treatment of Pediatric Migraine in the Emergency Department
Status: WITHDRAWN
Conditions: Migraine
Interventions: DRUG: Ketorolac|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of ASIMOMMY® Compared to Domperidone and Placebo in Increasing Breastfeeding: Randomized Single-Blind Controlled Trial in Indonesia
Status: COMPLETED
Conditions: Breastfeeding Mothers
Interventions: DRUG: ASIMOMMY®|DRUG: Domperidon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Three Different Doses of Neostigmine on the Reversal of Cisatracurium-induced Moderate Neuromuscular Blockade
Status: UNKNOWN
Conditions: Neuromuscular Blockade|Neuromuscular Blockade, Residual
Interventions: DRUG: Sevoflurane - Neostigmine 30|DRUG: Sevoflurane - Neostigmine 50|DRUG: Sevoflurane - Neostigmine 70|DRUG: TIVA - Neostigmine 30|DRUG: TIVA - Neostigmine 50|DRUG: TIVA - Neostigmine 70
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Regorafenib in Bevacizumab Refractory Recurrent Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Glioblastoma
Interventions: DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interscalene Catheter vs. Interscalene Liposomal Bupivacaine for Arthroscopic Rotator Cuff Repair
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Single injection peripheral nerve block with liposomal bupivacaine (Exparel)|PROCEDURE: Single injection peripheral nerve block with 0.25% bupivacaine and subsequent peripheral nerve catheter with 0.2% bupivacaine infusion via onQ pain pump
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coagulation Profile in Patients Undergoing Video Assisted Thorascopic Surgery (VATS) for Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Dalteparin (Fragmin®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Microalgae Extract Phaeosol Combined to Exercise in Healthy Overweight Women : Efficacy on Body Weight Management
Status: COMPLETED
Conditions: Overweight and Obesity|Body Weight Changes|Healthy Lifestyle|Exercise|Dietary Supplement
Interventions: DIETARY_SUPPLEMENT: Phaeosol group|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Myomectomy vs Uterine Artery Embolization vs GnRh Antagonist for AUB-L
Status: ACTIVE_NOT_RECRUITING
Conditions: Heavy Menstrual Bleeding|Fibroid Uterus
Interventions: OTHER: Groups 1 and 2 myomectomy and uterine artery embolization, respectively, are surgical/procedure|DRUG: Elagolix Oral Product
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Venetoclax and Azacitidine Combined With Homoharringtonine, Followed by Allo-HSCT for Intermediate and High-risk AML.
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Venetoclax, Azacitidine and Homoharringtonine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Serum Contraceptive Hormone Levels Between Normal Weight and Obese Users of the NuvaRing®
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: NuvaRing|DRUG: NuvaRing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Comparison of Characteristics of Bronchoalveolar Lavage Dusting and of Specific Questionnary Data in Healthy Volunteers and Patients Suffering From Sarcoidosis
Status: COMPLETED
Conditions: Sarcoidosis
Interventions: OTHER: Bronchoalveolar lavage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Cherry Powder Supplementation on Vascular Function
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Cherry powder|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Physiological Effects of 38°C vs. 22°C Fluid Therapy in Critically Ill Patients
Status: WITHDRAWN
Conditions: Critical Illness|Sepsis|Fluid Overload|Hemodynamic Instability
Interventions: OTHER: Body temperature|DRUG: Fluid bolus|OTHER: Room temperature
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Instantaneous Wave-Free Ratio and Fractional Flow Reserve for the Assessment of Non Culprit Lesions in Patients With ST-segment Elevation Myocardial Infarction
Status: UNKNOWN
Conditions: ST Segment Elevation Myocardial Infarction
Interventions: OTHER: FFR and iFR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Determining Equivalence Dose for Oral Versus Sublingual Administration of Tacrolimus in Hepatic Receptors
Status: COMPLETED
Conditions: Evidence of Liver Transplantation|Effects of Immunosuppressant Therapy
Interventions: DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicentre Study to Determine the Cardiotoxicity of R-CHOP Compared to R-COMP in Patients With Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: liposomal Doxorubicin|DRUG: Vincristin|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study for the Evaluation of Two Medical Devices on the Treatment of Head Lice Infestation
Status: RECRUITING
Conditions: Head Lice Infestation
Interventions: DEVICE: Paranix® Shampoo|DEVICE: Paranix® Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRO#0118: Decitabine Plus Mini Flu-Bu
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Decitabine plus Fludarabine and Busulfan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the Efficacy of a Marketed Dentifrice on Plaque and Gingivitis
Status: COMPLETED
Conditions: Plaque|Gingivitis
Interventions: DRUG: Arm & Hammer Advance White Brilliant Sparkle (Test product)|DRUG: Crest Cavity Protection Regular Toothpaste (Negative Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Fenoldopam in Solitary Partial Nephrectomy Surgery
Status: TERMINATED
Conditions: Partial Nephrectomy
Interventions: DRUG: Fenoldopam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Postural Assessment, Therapeutic Exercise and Orthotic Devices in the Prevention of Haemophilic Arthropathy
Status: COMPLETED
Conditions: Haemophilic Arthropathy|Orthosis|Foot Malalignment
Interventions: DEVICE: Orthotic devices and therapeutic exercise (Group A)|DEVICE: Orthotic devices (Group B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cryoballoon Pulmonary Vein Isolation: Time-to-Isolation Dependent Freeze Protocols Comparison
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Cryoballoon pulmonary vein isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Proximal Caries Infiltration and Detection
Status: TERMINATED
Conditions: Caries,Dental
Interventions: DEVICE: Resin infiltration|DEVICE: Fluoride varnish & Oral hygiene instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Laser-Assisted Gingival Depigmentation
Status: COMPLETED
Conditions: Hyperpigmentation; Melanin|Laser-Induced Hyperpigmentation
Interventions: DEVICE: Er,Cr:YSGG laser 2780 nm|DEVICE: Diode laser 940 nm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SCREEN-HFI (SCReening Evaluation of the Evolution of New Heart Failure Intervention Study)
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Spironolactone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ketogenic Diet Effects on the Frequency of Non Epileptic Seizures
Status: COMPLETED
Conditions: Non Epileptic Seizures|Functional Neurological Symptom Disorder|Conversion Disorder|Ketogenic Dieting
Interventions: DIETARY_SUPPLEMENT: ketogenic dieting|DIETARY_SUPPLEMENT: healthy dieting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Care Referrals to Community-based Lifestyle Programs for Management of Obesity
Status: COMPLETED
Conditions: Obesity|Lifestyle, Healthy|Community Based Programs|Primary Care Referrals
Interventions: BEHAVIORAL: Referral to weight loss program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lifestyle Interventions for Vitality and Empowerment in Seniors
Status: NOT_YET_RECRUITING
Conditions: Cognitive Change
Interventions: BEHAVIORAL: High Intensity Interval Resistance Training|BEHAVIORAL: Stretching, Balance, and Range of motion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of Sodium Pentaborate Pentahydrate in People With Overweight and Obesity
Status: NOT_YET_RECRUITING
Conditions: Overweight and Obesity
Interventions: DRUG: Sodium pentaborate pentahydrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study With Combination Treatment (Tamsulosin Hydrochloride and Solifenacin Succinate) in Male Patients With LUTS/BPH
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms|Prostatic Hyperplasia
Interventions: DRUG: tamsulosin hydrochloride|DRUG: solifenacin succinate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of OnabotulinumtoxinA in Premature Ejaculation
Status: TERMINATED
Conditions: Premature Ejaculation
Interventions: DRUG: OnabotulinumtoxinA|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LLLT and Russian Electrical Stimulation in Osteoarthritis
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: OTHER: Low level Laser Therapy and Russian electrical stimulation|OTHER: Placebo Laser and Russian electrical stimulation|OTHER: Low level Laser Therapy and Low level Laser Therapy plus Russian electrical stimulation|OTHER: Placebo Laser and Placebo Laser plus Russian electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Dose Ranging CHRONSEAL® Study in Venous Leg Ulcers
Status: UNKNOWN
Conditions: Chronic Venous Leg Ulcers
Interventions: DRUG: CHRONSEAL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Sapablursen (Formerly ISIS 702843, IONIS-TMPRSS6-LRx)
Status: TERMINATED
Conditions: Beta Thalassemia Intermedia
Interventions: DRUG: sapablursen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effectiveness of Two Family-based Therapies in Treating Young Children With Obsessive-Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: BEHAVIORAL: Cognitive Behavior Therapy|BEHAVIORAL: Relaxation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Graphic Novel for Patients Undergoing EUS-FNB
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Pancreatic Cancer|Pancreatic Cystic Lesions|Stress
Interventions: BEHAVIORAL: Graphic novel visualization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Bone Effects With Copaxone and Interferon in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Low Bone Density
Interventions: DRUG: Copaxone|DRUG: Interferon-beta 1a|DRUG: Interferon-beta 1b
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety of CHIR-258 (TKI258) in Advanced Solid Tumors
Status: TERMINATED
Conditions: Neoplasms|Cancer|Tumors
Interventions: DRUG: CHIR-258 (TKI258)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Radiobiological Effects in Skin Toxicities for Breast Cancer Patients With Pencil Beam Scanning Proton Therapy
Status: RECRUITING
Conditions: Breast Cancer|Breast Cancer Stage II|Breast Cancer Stage III|Breast Cancer Stage I
Interventions: RADIATION: Pencil Beam Scanning Proton Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Predimenol for Headache
Status: RECRUITING
Conditions: Headache
Interventions: DRUG: Predimenol tablet|DRUG: Predimenol tablet + Placebo tablet of Predimenol|DRUG: Placebo tablet of Predimenol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Indications and Evaluation of Microfat Grafting in Cleft Lip Nasal Deformities
Status: NOT_YET_RECRUITING
Conditions: Cleft Lip and Nose
Interventions: PROCEDURE: Microfat grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Co-administered With Canagliflozin in Healthy Fed and Fasted Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Canagliflozin and Metformin Extended Release (XR) Fixed Dose Combination [FDC]|DRUG: Canagliflozin 50 mg|DRUG: Canagliflozin 100 mg|DRUG: Metformin Extended Release (XR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Exercise Intensity in Obese Children and Adolescents
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: High intensity interval training|BEHAVIORAL: Moderate intensity continuous training|DIETARY_SUPPLEMENT: Nutritional advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Pasireotide Administered Monthly in Patients With Cushing's Disease
Status: COMPLETED
Conditions: Cushing's Disease
Interventions: DRUG: pasireotide LAR|DRUG: SOM230 LAR 30 mg|DRUG: SOM230 LAR 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bangkok Tenofovir Study, an HIV Pre-exposure Prophylaxis Trial, Bangkok, Thailand
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Tenofovir disoproxil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Health Wearables and College Student Health
Status: COMPLETED
Conditions: Behavior Change|Physical Activity|Young Adults|Technology|Intervention
Interventions: BEHAVIORAL: Polar M400 + Facebook Group (PM400+FG)|BEHAVIORAL: Facebook Only Group (FG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Ten-Week Study Evaluating The Effectiveness And Safety Of Zoloft In Children And Adolescents With A Diagnosis Of PTSD
Status: TERMINATED
Conditions: Stress Disorders, Post-Traumatic
Interventions: DRUG: Zoloft (Sertraline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial of Adipose-Derived Stem Cells in the Treatment of Pts With ST-elevation Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction|Coronary Arteriosclerosis|Cardiovascular Disease|Coronary Disease
Interventions: DRUG: Injection of ADRC's|OTHER: Injection of Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Tracking of Patients Diagnosed With Neurodegenerative Movement Disorders
Status: RECRUITING
Conditions: Neurodegenerative Diseases|sca3|MSA - Multiple System Atrophy|Ataxia|Synucleinopathies
Interventions: DRUG: 18F-PBR06|RADIATION: 18F-PBR06
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Videos and Simple Text to Empower Parents to Handle Their Sick Children
Status: COMPLETED
Conditions: Pediatrics|Efficacy, Self|Triage
Interventions: BEHAVIORAL: Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Adaptation of the Right Ventricle to Systemic Afterload
Status: COMPLETED
Conditions: Congenital Heart Disease With Systemic Right Ventricle
Interventions: OTHER: asymptomatic group|OTHER: symptomatic group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Gluteus Maximus Versus Gluteus Medius Strength On Back Muscles Performance In Patients With Sacroiliac Dysfunction
Status: NOT_YET_RECRUITING
Conditions: Sacroiliac Joint Dysfunction
Interventions: OTHER: Glutes maximus strength protocol|OTHER: Gluteus medius strength program|OTHER: Corrective Exercises|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effect of ReSpace™ Hydrogel on Reducing Rectal Radiation Dose in Radiotherapy for Cervical Cancer
Status: RECRUITING
Conditions: Uterine Cervical Neoplasms
Interventions: DEVICE: ReSpace™|DEVICE: gauze packing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Very Small Embryonic-like Stem Cells for Facial Skin Antiaging
Status: WITHDRAWN
Conditions: Stem Cell Transplant Complications|Skin Inflammation
Interventions: BIOLOGICAL: Very small embryonic-like stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Temsirolimus in Treating Patients With Recurrent or Persistent Cancer of the Uterus
Status: TERMINATED
Conditions: Recurrent Uterine Sarcoma|Uterine Carcinosarcoma
Interventions: DRUG: temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tulobuterol Patch Combined With Tiotropium Bromide for Relieving Dyspnea Symptom of Chronic Obstructive Pulmonary Disease
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: tulobuterol|DRUG: Tiotropium Bromide|DRUG: tiotropium bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Adjuvant Metformin for Operable Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Placebo|DRUG: Metformin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Spinal and General Anesthesia in Neonates Undergoing Herniorrhaphy
Status: RECRUITING
Conditions: Spinal Anesthesia|General Anesthesia|Neonates|Inguinal Herniorrhaphy
Interventions: DIAGNOSTIC_TEST: Spinal anesthesia|DIAGNOSTIC_TEST: General anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Integrated Treatment of OEF/OIF Veterans With PTSD & Substance Use Disorders
Status: COMPLETED
Conditions: Posttraumatic Stress Disorders|Combat Disorders|Alcohol Dependence|Drug Dependence
Interventions: BEHAVIORAL: Concurrent Treatment with Prolonged Exposure (COPE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT