pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Primary Prophylaxis of Gastric Variceal Bleed
Status: UNKNOWN
Conditions: Gastric Varices
Interventions: PROCEDURE: Balloon-occluded retrograde transvenous obliteration|PROCEDURE: Endoscopic cyanoacrylate injection|DRUG: N-butyl-2-cyanoacrylate|DRUG: Lauromacrogol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Individualizing Hemophilia Bypassing Agent Therapy Utilizing Thromboelastography
Status: WITHDRAWN
Conditions: Hemophilia A With Inhibitors
Interventions: OTHER: Thromboelastography-Guided Treatment Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Impaired Mobility in Chronic Illness Constitution of a Cohort
Status: RECRUITING
Conditions: Joint Osteoarthritis|Atherosclerosis of the Distal Arteries, Without Gangrene|Parkinson Disease|Chronic Obstructive Pulmonary Disease, Unspecified|Obesity, Unspecified
Interventions: OTHER: Development of a screening algorithm designed to determine a "dysmobility" profile in patients with chronic illness.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial to Evaluate Efficacy and Safety of Pembrolizumab and Gemcitabine in HER2-negative ABC
Status: COMPLETED
Conditions: Advanced Breast Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD34 Selection of the Peripheral Blood Stem Cell Graft for Autologous Transplant
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: high dose chemo then auto hematopoietic cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet-rich Fibrin and Autogenous Bone vs Enamel Matrix Derivative and Autogenous Bone in Intrabony Defects
Status: UNKNOWN
Conditions: Periodontal Bone Loss|Periodontal Attachment Loss
Interventions: PROCEDURE: Periodontal surgery with Enamel Matrix Derivative|PROCEDURE: Periodontal surgery with Platlet Rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ginseng Extract on Improvement of Bone Metabolism in Menopausal Women
Status: COMPLETED
Conditions: Osteopenia
Interventions: DIETARY_SUPPLEMENT: Ginseng extract 1g|DIETARY_SUPPLEMENT: Ginseng extract 3g|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of Hemay007 in Patients With Active Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: Hemay007|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Blood Flow Restriction Within Warm-up.
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Warm-up + Blood Flow Restriction cuff (smart-cuff pro device, acting as pressurized tourniquet)|OTHER: Warm-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of the MDR1 Genotype on Blood Levels of Indinavir and Saquinavir in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy|HIV Infections
Interventions: DRUG: Midazolam|DRUG: Indinavir|DRUG: Saquinavir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Postprandial Glycemia After Eating a Pasta Dish Made With Resistant Starch.
Status: COMPLETED
Conditions: Postprandial Glycemia|Resistant Starch
Interventions: OTHER: Pasta dish with resistant starch|OTHER: Original version of pasta dish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Role of Adjuvant Albendazole After Pulmonary Hydatid Cyst Resection
Status: RECRUITING
Conditions: Pulmonary Hydatid Cyst
Interventions: DRUG: Albendazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Characterization of AmnioExcel Plus in Two Treatment Paradigms
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: Amnio Excel + weekly|DEVICE: Amnio Excel + max every 2 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oculomotor and Gaze Stability Exercises on the Improvement of Balance After Stroke
Status: COMPLETED
Conditions: Stroke|Distorted; Balance
Interventions: OTHER: Oculomotor and Gaze Stability Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inter-observer Reliability of the TRiP(Cast) Score in Patients With Trauma to a Lower Limb Requiring Immobilisation
Status: RECRUITING
Conditions: Venous Thromboembolism|Deep Vein Thrombosis|Pulmonary Embolism|Thromboprophylaxis|Lower Limb Trauma|Immobilisation Syndrome
Interventions: OTHER: Assessment of the TRiP(cast) score
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Incrediwear ACL MCL Arthroscopic Surgery Recovery Study
Status: NOT_YET_RECRUITING
Conditions: Arthroscopic Surgical Procedures|Anterior Cruciate Ligament Reconstruction
Interventions: OTHER: Activated Incrediwear Products|OTHER: Sham Incrediwear Products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chloral Hydrate to Perform Auditory Brainstem Response (ABR)
Status: COMPLETED
Conditions: Auditory Brainstem Response in Children|Sedation With Chloral Hydrate
Interventions: DRUG: Chloral Hydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Real World Evidence of the Effectiveness of Paritaprevir/Ritonavir (r) - Ombitasvir, + Dasabuvir Without Ribavirin in Participants With Chronic Hepatitis C and Compensated Liver Cirrhosis in the Russian Federation
Status: COMPLETED
Conditions: Chronic Hepatitis C
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Open-Label Trial of Resistant Potato Starch in Patients With Cirrhosis and Overt Hepatic Encephalopathy
Status: RECRUITING
Conditions: Hepatic Encephalopathy|Cirrhosis
Interventions: OTHER: Resistant Potato Starch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Entinostat With Nivolumab Plus Ipilimumab in Previously Treated Renal Cell Carcinoma
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Entinostat|DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Life Intervention for Patients Receiving Radiation Therapy for Advanced Cancer Treatment and Their Caregivers
Status: COMPLETED
Conditions: Quality of Life|Advanced Cancer
Interventions: BEHAVIORAL: Quality of life counseling|OTHER: Video-conference quality of life counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MC-5A for Chemotherapy Induced Peripheral Neuropathy
Status: COMPLETED
Conditions: Neuropathy, Paraneoplastic
Interventions: DEVICE: MC-5A|DRUG: Sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tadekinig Alfa (IL-18BP) Rescue Therapy for CAR T Cell Related Cytokine Release Syndrome (CRS) and HLH-like Syndrome
Status: RECRUITING
Conditions: CRS - Cytokine Release Syndrome|HLH
Interventions: DRUG: Tadekinig alfa (IL-18BP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Different Dose Levels of Ad26.COV2.S in Healthy Adolescents From 12 to 17 Years Inclusive
Status: COMPLETED
Conditions: Coronavirus Disease-2019 (COVID-19) Prevention
Interventions: BIOLOGICAL: Ad26.COV2.S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing Pedicle Screw Systems for the Treatment of Adolescent Paediatric Spine Deformity
Status: WITHDRAWN
Conditions: Adolescent Idiopathic Scoliosis
Interventions: DEVICE: MESA Rail Deformity System|DEVICE: DePuy Synthes USS II System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Camrelizumab Plus Rivoceranib (Apatinib) as Adjuvant Therapy in Patients With Hepatocellular Carcinoma (HCC) at High Risk of Recurrence After Curative Resection or Ablation
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma (HCC)
Interventions: DRUG: Camrelizumab|DRUG: Rivoceranib (Apatinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin C Effectiveness in Preventing Urinary Tract Infections After Gynecological Surgeries
Status: RECRUITING
Conditions: Catheter-Associated Urinary Tract Infection
Interventions: DRUG: Ascorbic Acid 1000 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Pegylated Somatropin (PEG Somatropin) in the Treatment of Children With Growth Hormone Deficiency
Status: UNKNOWN
Conditions: Growth Hormone Deficiency
Interventions: BIOLOGICAL: PEG-somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized "Alberta" Diet for Prevention of Relapse in Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: BEHAVIORAL: Alberta Anti-inflammatory diet|BEHAVIORAL: Canada's Food Guide Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study for the Treatment With Interferon-ß-1a (IFNß-1a) of COVID-19 Patients
Status: TERMINATED
Conditions: COVID-19 Virus Infection
Interventions: DRUG: Interferon-ß-1a|COMBINATION_PRODUCT: Standard of Care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ASTX660 as a Single Agent and in Combination With ASTX727 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia (AML)
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: ASTX660|DRUG: ASTX727
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of 6R-BH4 Treatment in Coronary Artery Disease (OXBIO Study)
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: 6R-BH4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stroke Therapy With Brain Oscillation Synchronized Stimulation
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Negative peak triggered 100 Hz triplet burst TMS|DEVICE: 1 Hz rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of a 1-dose Regimen of a Zoster Vaccine Versus Different 2-dose Regimens in Participants ≥ 70 Years of Age. (V211-043)
Status: COMPLETED
Conditions: Prevention of : Herpes-Zoster
Interventions: BIOLOGICAL: Zostavax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Differences by Sex and Genotype in the Effects of Stress on Executive Functions
Status: RECRUITING
Conditions: Stress
Interventions: DRUG: Methylphenidate|DRUG: Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluate the Safety and Efficacy of Caspofungin Acetate as Empirical Therapy in Chinese Adults With Persistent Fever and Neutropenia (0991-055)
Status: COMPLETED
Conditions: Fungal Infection
Interventions: DRUG: MK0991, caspofungin acetate / Duration of Treatment:
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regular Use Effect of Inhaled Ipratropium Bromide on Airway Responsiveness to Methacholine in Well-controlled Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Ipratropium Metered Dose Inhaler|DRUG: placebo metered dose inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sinus Augmentation in the Posterior Maxillary Region: a Case Report of 0mm Bone Height.
Status: COMPLETED
Conditions: Bone Resorption
Interventions: PROCEDURE: Conventional sinus lift surgery|PROCEDURE: Two-stage-sinus-lift procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closed-loop syncHronization vErsuS convenTional Synchronization in sPontaneously Breathing Adult Nonivasive ventilationPatients
Status: NOT_YET_RECRUITING
Conditions: Acute Respiratory Failure|Acute Respiratory Distress Syndrome|Chronic Respiratory Failure
Interventions: OTHER: close-loop synchronization controller with spontaneous mode|OTHER: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Family-Professional Collaboration on Functional Goals Achievement of Children With Cerebral Palsy and Caregivers' Quality of Life and Burden
Status: COMPLETED
Conditions: Cerebral Palsy|Collaborative Intervention Process|Functional Goals Achievement
Interventions: OTHER: family-professional collaboration practice model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: AG200-15 Transdermal Contraceptive Delivery System (TCDS) of Levonorgestrel and Ethinyl Estradiol
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ortho-Cyclen|DRUG: AG200-15
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reporting, Evaluating, Preventing and Treating the Cardiotoxicity Induced by Anticancer Drugs During a Specific Cardio-oncology Consult and Follow up in Routine Care
Status: RECRUITING
Conditions: Cardiovascular Complication|Cardiovascular Insufficiency|Cardiac Complication|Oncologic Complications|Cardiac Insufficiency|Metabolic Disorder|Vascular Disorder|Cardiac Disorder
Interventions: DRUG: Anti-Cancer Agents
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intervention With Selenium and Q10 on Cardiovascular Mortality and Cardiac Function in the Elderly Population in Sweden
Status: COMPLETED
Conditions: Cardiovascular Mortality|Cardiac Function
Interventions: DIETARY_SUPPLEMENT: Selenium and ubiquinon (Q10) combined
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: STUDY TO DETERMINE THE EFFICACY AND SAFETY OF STANDARD SCHEDULE VERSUS A NEW ALGORITHM OF DOSE REDUCTIONS IN ELDERLY AND UNFIT NEWLY DIAGNOSED MULTIPLE MYELOMA PATIENTS RECEIVING LENALIDOMIDE PLUS STEROIDS
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reinforcement of Placebo Response in Knee Osteoarthritis: A Randomised Trial
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BEHAVIORAL: Illness perception conversation|BEHAVIORAL: research motivation conversation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enriched Canned Tuna With Fibre or Polyphenols on Satiety
Status: COMPLETED
Conditions: Overweight
Interventions: OTHER: Control Canned Tuna|OTHER: Enriched Canned Tuna Variety 1|OTHER: Enriched Canned Tuna Variety 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Non-pharmacological Treatment for Pain After Spine Surgery
Status: RECRUITING
Conditions: Low Back Pain|Chronic Pain|Surgery|Back Pain, Low|Back Pain Lower Back Chronic
Interventions: BEHAVIORAL: Standard Care (SC)|BEHAVIORAL: Enriched Pain Management Pathway (EPM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extinction of Fear Memories With Glucocorticoids in Veterans With PTSD
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: Dexamethasone|DRUG: Placebo (sugar pill)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kinetics of Surfactant Proteins, Phosphatidylcholine and Body Water in Intensive Care Unit (ICU)
Status: COMPLETED
Conditions: ARDS|Sepsis Syndrome
Interventions: DRUG: Injection of 1-13 Carbon Leucine and deuterated water
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Study of Cisplatin-Etoposide Versus an Etoposide Regimen Without Cisplatin in Extensive Small-Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Carcinoma, Extensive Disease
Interventions: DRUG: Cisplatin + etoposide|DRUG: Epirubicin + ifosfamide + etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Evaluating Concurrent Whole Brain Radiotherapy and Iniparib in Multiple Non Operable Brain Metastases
Status: TERMINATED
Conditions: Brain Metastases
Interventions: RADIATION: Radiation combined with iniparib (BSI-201)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hormone Therapy and Radiation Therapy or Hormone Therapy and Radiation Therapy Followed by Docetaxel and Prednisone in Treating Patients With Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Dexamethasone|DRUG: Prednisone|DRUG: docetaxel|DRUG: Oral antiandrogen|RADIATION: Radiation therapy|DRUG: LHRH agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This Study Will Examine the Clinical Effectiveness of Tafamidis in Patients With Mixed Phenotype Hereditary Transthyretin Amyloidosis
Status: COMPLETED
Conditions: Hereditary Transthyretin Amyloidosis (ATTRv) Cardiomyopathy (CM), Mixed Phenotype
Interventions: DRUG: tafamidis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HER2-specific Chimeric Antigen Receptor (CAR) T Cells for Children With Ependymoma
Status: RECRUITING
Conditions: Ependymoma
Interventions: BIOLOGICAL: HER2 Specific CAR T Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Desflurane Preconditioning in Hepatectomies
Status: COMPLETED
Conditions: Ischemia Reperfusion Injury
Interventions: DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lateral Sinus Augmentation Using L-PRF as Sole Graft Material
Status: COMPLETED
Conditions: Maxillary Diseases
Interventions: PROCEDURE: L-PRF|PROCEDURE: L-PRF mixed with xenograft|PROCEDURE: xenograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Effectiveness of Aclidinium Bromide/Formoterol Fumarate Dihydrate in Chronic Obstructive Pulmonary Disease
Status: WITHDRAWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Aclidinium bromide/formoterol fumarate combination|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability and Food Effect Study of Gelatin Formulation and Immediate Release Tablet Formulation of Afuresertib
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: GSK2110183 Gelatin Capsule|DRUG: GSK2110183 IR Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not Responded to Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor|Central Nervous System Tumor|Lymphoma|Leukemia
Interventions: DRUG: Neratinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subglottic Secretions Surveillance to Predict Bacterial Pathogens Involved in Ventilator-associated Pneumonia
Status: COMPLETED
Conditions: Ventilator-associated Pneumonia
Interventions: DEVICE: Endotracheal tubes not allowing SSD|DEVICE: Endotracheal tubes allowing SSD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Efficacy of PEAR-004 in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DEVICE: PEAR-004|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study of Tocilizumab in Patients With Active Rheumatoid Arthritis (RA) and an Inadequate Response to Current Non-Biologic DMARDs and/or Anti-TNF Therapy.
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab [RoActemra/Actemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of CSL's 2010/2011 Formulation of Enzira® in a Healthy Adult Population
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: CSL's 2010/2011 Formulation of Enzira® Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Olive Oil on Erythrocyte Membrane Fatty Acid Contents in Hemodialysis Patients
Status: COMPLETED
Conditions: Hemodialysis
Interventions: DIETARY_SUPPLEMENT: Stir-fried olive oil group|DIETARY_SUPPLEMENT: Natural olive oil group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: SELVA: A Phase 3 Study Evaluating QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Microcystic Lymphatic Malformations
Status: RECRUITING
Conditions: Microcystic Lymphatic Malformation
Interventions: DRUG: QTORIN 3.9% Rapamycin Anhydrous Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial in RAI-Refractory Thyroid Carcinoma Evaluating BRAF & MEK Blockade for Re-differentiation Therapy
Status: UNKNOWN
Conditions: Thyroid Cancer
Interventions: DRUG: dabrafenib and trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Of The Effectiveness Of The Peer Bullying Consultancy Program Based On The Interpersonal Relations Model
Status: COMPLETED
Conditions: Perr Bulling, Middle School Child, School Nursing, Peplau-Interpersonel Relationship Theory
Interventions: OTHER: Peer Bullying Counseling Program based on the Interpersonal Relationship Model
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Infant Study of Inhaled Saline in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: 7% Hypertonic Saline (HS)|DRUG: 0.9% Isotonic Saline (IS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab Maintenance Following First-Line Platinum Based Chemotherapy in Patients With Metastatic Squamous - Non-Small Cell Lung Cancer (sNSCLC)
Status: TERMINATED
Conditions: Metastatic Squamous Non-small Cell Lung Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Self-Injury Treatment and Recovery in Veterans
Status: NOT_YET_RECRUITING
Conditions: Self-Injurious Behavior
Interventions: BEHAVIORAL: Treatment for Self-Injurious Behaviors|OTHER: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanical Bowel Preparation and Oral Antibiotics Before Colon Cancer Surgery
Status: TERMINATED
Conditions: Colon Cancer
Interventions: DRUG: Sennosides colonic preparation|DRUG: Oral Gentamycin|DRUG: Oral Ornidazole|DRUG: Oral placebo Gentamycin|DRUG: Oral placebo Ornidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Programmable Timer in the Bladder Rehabilitation Treatment of OAB
Status: COMPLETED
Conditions: Overactive Bladder|Urinary Incontinence
Interventions: BEHAVIORAL: Bladder rehabilitation|BEHAVIORAL: Bladder rehabilitation with programmable timer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular Occlusion for Optimizing Functional Improvement in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Blood Flow Restriction
Interventions: DEVICE: Blood Flow Restriction (by using smart-cuff pro devices, acting as pressurized tourniquet) combined low load strengh training|OTHER: Standardised low load strength training|DEVICE: Sham-BFR (by using smart-cuff pro devices, acting as pressurized tourniquet) combined with low load strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Intranasal Naloxone on Gambling Urges and Craving in Gambling Disorder
Status: UNKNOWN
Conditions: Pathological Gambling|Gambling Disorder|Opioid Antagonist|Naloxone
Interventions: DRUG: Naloxone hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Occurrence of Antibodies Cross-reacting With Autoantigens in Primary EBV Infection
Status: RECRUITING
Conditions: Epstein-Barr Virus (EBV) Infection
Interventions: OTHER: Data collection: Participant characteristics (Illness course, complications of primary EBV infection and provided treatments)|OTHER: Data collection: blood samples (analysed for EBV serology, auto-antibody-testing/biobanking, RNA expression analyses, procalcitonin)|OTHER: Data collection: Patient reported outcome (Fatigue questionnaires)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preoperative Intervention to Reduce Delirium After Cardiac Surgery
Status: UNKNOWN
Conditions: Cardiac Surgery
Interventions: BEHAVIORAL: Cognitive therapy|BEHAVIORAL: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Denosumab in Erosion Healing in RA
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Denosumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors
Status: COMPLETED
Conditions: Childhood Central Nervous System Germ Cell Tumor|Childhood Choroid Plexus Tumor|Childhood Craniopharyngioma|Childhood Ependymoblastoma|Childhood Grade I Meningioma|Childhood Grade II Meningioma|Childhood Grade III Meningioma|Childhood High-grade Cerebellar Astrocytoma|Childhood High-grade Cerebral Astrocytoma|Childhood Infratentorial Ependymoma|Childhood Low-grade Cerebellar Astrocytoma|Childhood Low-grade Cerebral Astrocytoma|Childhood Medulloepithelioma|Childhood Mixed Glioma|Childhood Oligodendroglioma|Childhood Supratentorial Ependymoma|Recurrent Childhood Brain Stem Glioma|Recurrent Childhood Cerebellar Astrocytoma|Recurrent Childhood Cerebral Astrocytoma|Recurrent Childhood Ependymoma|Recurrent Childhood Medulloblastoma|Recurrent Childhood Pineoblastoma|Recurrent Childhood Subependymal Giant Cell Astrocytoma|Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor|Recurrent Childhood Visual Pathway and Hypothalamic Glioma
Interventions: DRUG: O6-benzylguanine|DRUG: temozolomide|BIOLOGICAL: filgrastim|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation for Severe Self-Injurious Behaviour in Children
Status: RECRUITING
Conditions: Self-Injurious Behavior|Autism Spectrum Disorder
Interventions: DEVICE: DBS ON|DEVICE: DBS OFF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of the 7 Days Tailored Therapy as the 1st Eradication of H. Pylori Infection
Status: RECRUITING
Conditions: Helicobacter Infection
Interventions: DRUG: 10 day sequential therapy (Esomeprazole, amoxicillin, clarithromycin, metronidazole)|DRUG: 7 day tailored PPI triple therapy (clarithromycin-containing triple therapy)|DRUG: 7 day moxifloxacin based triple therapy [Esomeprazole, Moxifloxacin, Amoxicillin]|DRUG: 7 or 14 days tailored EBMT therapy group (bismuth quadruple therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UARK 2006-15: A Study of Tandem Transplants With or Without Bortezomib and Thalidomide
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Interim/Maintenance Dexamethasone|DRUG: Induction/Consolidation Dexamethasone|DRUG: Induction/Consolidation Cisplatin|DRUG: Induction/Consolidation Adriamycin|DRUG: InductionConsolidation Cyclophosphamide|DRUG: Induction/Consolidation Etoposide|DRUG: Induction Pegfilgrastim|DRUG: Transplant 1 Dexamethasone|DRUG: Transplant 1 Cisplatin|DRUG: Transplant 1 Adriamycin|DRUG: Transplant 1 Cyclophosphamide|DRUG: Transplant 1 Etoposide|DRUG: Transplant 1 Melphalan|DRUG: Transplant 1 and 2 Pegfilgrastim|PROCEDURE: Autologous Peripheral Blood Stem Cell Transplant (ASCT)|DRUG: Transplant 2 Carmustine|DRUG: Transplant 2 Etoposide|DRUG: Transplant 2 Cytarabine|DRUG: Transplant 2 Melphalan|DRUG: Transplant 2 Dexamethasone|DRUG: Transplant 1 and 2 Bortezomib|DRUG: Transplant 1 and 2 Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Famitinib Plus SHR6390 and Endocrine Therapy in the Treatment of HR-positive, HER2-negative Advanced Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Famitinib|DRUG: SHR6390|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Fish Consumption on Polyunsaturated Fatty Acid (PUFA) Status
Status: COMPLETED
Conditions: Polyunsaturated Fatty Acid (PUFA) Status
Interventions: DIETARY_SUPPLEMENT: Fish|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Denosumab, Teriparatide or Both for the Treatment of Postmenopausal Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: denosumab|DRUG: teriparatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Montelukast in Non Alcoholic Steatohepatitis (NASH)
Status: COMPLETED
Conditions: Non Alcoholic Steatohepatitis
Interventions: OTHER: Placebo|DRUG: Montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Silastic Ring Gastric Bypass Versus Sleeve Gastrectomy for Type 2 Diabetes Mellitus in Obese Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Obesity
Interventions: PROCEDURE: Laparoscopic Silastic Ring Roux-en-Y Gastric Bypass|PROCEDURE: Laparoscopic Sleeve gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Recurrent Hepatitis C After Liver Transplantation
Status: COMPLETED
Conditions: Liver Transplantation|Hepatitis C
Interventions: DRUG: Ribavirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Neural Correlates of Empathogenic and Affiliative Actions of Oxytocin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Determination of the Role of Oxygen in Suspected Acute Myocardial Infarction by Biomarkers
Status: COMPLETED
Conditions: Acute Myocardial Infarction (AMI)|Acute Coronary Syndrome (ACS)|ST Elevation (STEMI) Myocardial Infarction|Ischemic Reperfusion Injury|Non-ST Elevation (NSTEMI) Myocardial Infarction|Angina, Unstable
Interventions: DRUG: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for Comparison of Canagliflozin Versus Alternative Antihyperglycemic Treatments on Risk of Heart Failure Hospitalization and Amputation for Participants With Type 2 Diabetes Mellitus and the Subpopulation With Established Cardiovascular Disease
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Cardiovascular Diseases
Interventions: DRUG: Canagliflozin|DRUG: Empagliflozin|DRUG: Dapagliflozin|DRUG: Dipeptidyl Peptidase-4 (DPP-4) Inhibitors|DRUG: Glucagon-like Peptide-1 (GLP-1) Agonist|DRUG: Anti-hyperglycemic Agents (AHA)|DRUG: Thiazolidinediones (TZD)|DRUG: Sulfonylureas (SU)|DRUG: Insulin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Selective TAE to Severely Bleeding Peptic Ulcers After Their Initial Endoscopic Hemostasis
Status: COMPLETED
Conditions: Bleeding|Peptic Ulcer|Arterial Embolization
Interventions: PROCEDURE: TAE|PROCEDURE: No TAE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Pain Education in Addition to Usual Care in Chronic Pain.
Status: RECRUITING
Conditions: Chronic Pain|Musculoskeletal Pain
Interventions: OTHER: Pain neuroscience education|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: RALPPS in Patients With Hilar and Intrahepatic Cholangiocarcinoma
Status: COMPLETED
Conditions: Hilar Cholangiocarcinoma|Intrahepatic Cholangiocarcinoma
Interventions: PROCEDURE: RALPPS|PROCEDURE: portal vein embolization + major liver resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 3 Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Heterozygous for F508del and a Minimal Function Mutation (F/MF)
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: VX-121/TEZ/D-IVA|DRUG: ELX/TEZ/IVA|DRUG: IVA|DRUG: Placebo (matched to VX-121/TEZ/D-IVA)|DRUG: Placebo (matched to ELX/TEZ/IVA)|DRUG: Placebo (matched to IVA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Pharmacokinetics and Bioavailability of Carbon-14 ([14C])-Labelled Oxytocin
Status: WITHDRAWN
Conditions: Healthy Women of Child Bearing Potential
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Immunogenicity of Two Doses, Administered Three Weeks Apart, of Two(Surface Antigen Adjuvanted With MF59C.1) Influenza Vaccines in Non-Elderly Adult and Elderly Subjects
Status: COMPLETED
Conditions: Pandemic Influenza Disease
Interventions: BIOLOGICAL: Influenza vaccine surface antigen adjuvanted with MF59
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: the Efficacy of Fetal Arterial and Venous Doppler Indices in Predicting Perinatal Outcome
Status: UNKNOWN
Conditions: Gestational Diabetes|Pre-Gestational Diabetes|IUGR|Macrosomia, Fetal
Interventions: DIAGNOSTIC_TEST: Fasting blood sugar, 2 hours postprandial, HBA1C ,Ultrasound and Doppler study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Effectiveness of Brief HIV Care Counseling
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: BEHAVIORAL: Behavioral self-regulation Phone counseling to improve HIV care|BEHAVIORAL: Behavioral self-regulation Office counseling to improve HIV care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Surgical or Conservative Approach in Patients With Adrenal Incidentalomas
Status: UNKNOWN
Conditions: Adrenal Incidentaloma|Subclinical Hypercortisolism
Interventions: PROCEDURE: adrenalectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptance and Commitment Therapy to Improve Social Support for Veterans With PTSD
Status: ACTIVE_NOT_RECRUITING
Conditions: Post-traumatic Stress Disorder
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy to Improve Social Support for Veterans with PTSD|BEHAVIORAL: Present-Centered Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nitrites, Skeletal Muscle Mitochondrial Bioenergetics, and Physical Activity in Old Age
Status: COMPLETED
Conditions: Aging|Sedentary Lifestyle|Frailty
Interventions: DRUG: Placebos|DRUG: 20mg sodium nitrite tid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation (tDCS) in Treatment-resistant Depression
Status: COMPLETED
Conditions: Therapy Resistant Major Depression
Interventions: DEVICE: Transcranial direct current stimulation (tDCS) - Eldith DC-Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcutaneous Electrical Nerve Stimulation on Chemotherapy-Induced Peripheral Neuropathy
Status: COMPLETED
Conditions: Chemotherapy-Induced Peripheral Neuropathy
Interventions: DEVICE: Placebo Administration|OTHER: Questionnaire Administration|DEVICE: Transcutaneous Electrical Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nurse Delivered Cell Phone Adherence Intervention (Pick It UP)
Status: COMPLETED
Conditions: Medication Adherence
Interventions: BEHAVIORAL: Adherence Counseling|BEHAVIORAL: General Health Counseling|BEHAVIORAL: Text Messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double-Blind, Placebo-Controlled, Crossover Study of Trans Sodium Crocetinate in Healthy Volunteers Exercising at Altitude
Status: COMPLETED
Conditions: Healthy Volunteers With Induced Hypoxia
Interventions: DRUG: Trans Sodium Crocetinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Hypo-fractionated Intensity- Modulated Radiation Therapy to Standard- Fractionated IMRT Along With Chemotherapy and Immunotherapy for Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer Stage
Interventions: RADIATION: Hypo-Fractionation|RADIATION: Standard-Fractionation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Urgent Start of Highly Active Antiretroviral Treatment (HAART)
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|Immune Reconstitution Inflammatory Syndrome
Interventions: OTHER: Urgent ART|OTHER: Early ART
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nimotuzumab in Combination With Paclitaxel Liposome and Carboplatin (TP Regimen) for the Advanced NSCLC Patients
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Nimotuzumab and TP regimen|DRUG: TP regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyberdyne HAL, TecnoBody D-Wall, and Walker View 3.0 SCX Combined Treatment
Status: COMPLETED
Conditions: Mosaicplasty|Cyberdyne|Single Joint|TecnoBody
Interventions: DEVICE: Combined treatment of Cyberdyne HAL single joint with TecnoBody D-Wall and Walker View 3.0 SCX devices
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TQB2618 Injection Combined With Penpulimab Injection in the Treatment of Patients With Recurrent/Metastatic Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: TQB2618 Injection, Pempulimab Injection, Cisplatin Injection, Gemcitabine Hydrochloride Injection|DRUG: Penpulimab injection, Cisplatin Injection, Gemcitabine Hydrochloride Injection|DRUG: TQB2618 injection; Penpulimab injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Non-steroidal Anti-inflammatory Drugs(NSAID) to Colorectal Cancer Patients
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Indomethacin, celecoxib, esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Ketamine Effectiveness in Reducing Intramuscular Injection Pain Before Sedation Among Children
Status: COMPLETED
Conditions: Pain|Intranasal Ketamine
Interventions: DRUG: Ketamine|DRUG: Sterile water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Microarchitecture at the Radius: a Pilot Comparison Between Children With Cystic Fibrosis and Healthy Controls
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DEVICE: Peripheral quantitative computed tomography (pQCT)|DEVICE: Dual X-ray absorptiometry (DXA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p