pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Acceptability and Tolerability of Magnetic Assisted Capsule Endoscopy Compared to Gastroscopy
Status: COMPLETED
Conditions: Dyspepsia
Interventions: PROCEDURE: gastroscopy|DEVICE: magnetic assisted capsule endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Investigation of the Efficacies of a Resveratrol Formula on Improvement of Skin Conditions and Inflammatory Related Factors
Status: COMPLETED
Conditions: Skin Conditions|Proinflammatory Cytokines
Interventions: DIETARY_SUPPLEMENT: Resveratrol drink|DIETARY_SUPPLEMENT: Placebo drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of a Medication Wallet Card
Status: COMPLETED
Conditions: Comorbidity|Medication Therapy Management|Polypharmacy
Interventions: DEVICE: Medication Wallet Card|DEVICE: Reminder Card
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Use of STRATAFIX Suture Device Compared to Standard-of-care for Deep Tissue Closure in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Wound; Knee
Interventions: DEVICE: STRATIFIX|DEVICE: VICRYL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Long-term Follow-up Study in Participants Who Received CTX001
Status: ENROLLING_BY_INVITATION
Conditions: Beta-Thalassemia|Thalassemia|Sickle Cell Disease|Hematologic Diseases|Hemoglobinopathies|Genetic Diseases, Inborn|Sickle Cell Anemia
Interventions: BIOLOGICAL: CTX001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Establishment of Multiple Point Prediction Model About Tacrolimus Metabolic Differences Based on Genetic Network After Liver Transplantation and the Application of Multicenter
Status: UNKNOWN
Conditions: Cirrhosis, Liver
Interventions: DRUG: Tacrolimus（FK506）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: EVOO Coratina Intervention on Lipids in Non-diabetic Hypertensive Patients Undergoing Hemodialysis (EVOOC-3H)
Status: UNKNOWN
Conditions: Chronic Kidney Disease Stage V
Interventions: DIETARY_SUPPLEMENT: Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Docosahexaenoic Acid on the Inflammatory Response and Clinical Outcomes From Surgical Patients
Status: COMPLETED
Conditions: Severe Sepsis|Organ Dysfunction Syndrome
Interventions: DIETARY_SUPPLEMENT: Docosahexaenoic acid|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Flibanserin Versus Placebo in Premenopausal Women With HSDD
Status: COMPLETED
Conditions: Sexual Dysfunctions, Psychological
Interventions: DRUG: 50 mg qhs|DRUG: 100 mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Learning-curve-based Simulation Training for Bronchoscopic Intubation
Status: COMPLETED
Conditions: Flexible Bronchoscopy|Simulation Training|Intubation Time
Interventions: OTHER: learning-curve-based training modality|OTHER: fixed-training-time training modality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Dyskinesia in Parkinson's Disease (Study P04501)
Status: COMPLETED
Conditions: Parkinson Disease|Movement Disorders|Central Nervous System Diseases|Neurodegenerative Diseases|Brain Diseases
Interventions: DRUG: Preladenant|DRUG: Preladenant|DRUG: Preladenant|DRUG: Preladenant|DRUG: Placebo|DRUG: L-dopa|DRUG: Other Parkinson's Disease treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I, Double-Blind,Placebo, MAD Study to Evaluate the Safety, Tolerability, PK, and PD of AMG 333 in Healthy Subjects and Migraine Subjects
Status: TERMINATED
Conditions: Migraine
Interventions: DRUG: AMG 333|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Physiological Responses at the Anterior Surface of Two (Hydrophobic Acrylic) Intraocular Lens Models
Status: UNKNOWN
Conditions: Age Related Cataracts
Interventions: DEVICE: Vivinex XY1|DEVICE: Vivinex XY1A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Research on the Biological Mechanism of the Efficacy of Psychotherapy for Depression Based on the fNIRS
Status: RECRUITING
Conditions: Depressive Disorder
Interventions: DRUG: Antidepressant|OTHER: Psychotherapy IPT|OTHER: The combination of antidepressant and IPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Shockwave Therapy Versus Focused Shockwave Therapy in Patients With Lateral Epicondylitis
Status: NOT_YET_RECRUITING
Conditions: Epicondylitis
Interventions: COMBINATION_PRODUCT: Combined shockwave therapy & conventional therapy , focused shockwave therapy& conventional therapy , conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthy Eating for Reproductive Health: Greenville
Status: WITHDRAWN
Conditions: Polycystic Ovarian Syndrome|Infertility|Obesity|Overweight
Interventions: BEHAVIORAL: Vegan diet|BEHAVIORAL: Low calorie diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of a Vaccine in Combination With β-glucan and GM-CSF in People With Neuroblastoma
Status: RECRUITING
Conditions: Neuroblastoma
Interventions: DIETARY_SUPPLEMENT: β-glucan|DRUG: GM-CSF|BIOLOGICAL: OPT-821
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of High-intensity Focused Ultrasound Tumor Treatment System(Super Knife) in the Treatment of Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DEVICE: a high-intensity focused ultrasound tumor treatment system (Super Knife)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Descartes-11 Consolidation Treatment in Patients With High-Risk Multiple Myeloma Who Have Residual Disease After Induction Therapy
Status: COMPLETED
Conditions: Myeloma Multiple
Interventions: BIOLOGICAL: Descartes 11
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Echothiophate Iodide for the Prevention of Progression of Myopia
Status: UNKNOWN
Conditions: Myopia
Interventions: DRUG: Echothiophate Iodide 0.03% Ophthalmic Solution|DRUG: Carboxymethylcellulose Sodium (0.5%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Physical Activity Measured Through Accelerometers and Its Association With Endothelial Function in Young Patients With Fontan Physiology
Status: COMPLETED
Conditions: Heart Defects
Interventions: OTHER: Physical activity measures via Actigraph GT3X+ accelerometers for 7 consecutive days
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Yttrium Y 90 Glass Microspheres and Capecitabine in Treating Patients With Liver Cholangiocarcinoma or Liver Metastases
Status: COMPLETED
Conditions: Liver Cancer|Metastatic Cancer
Interventions: DRUG: capecitabine|RADIATION: yttrium Y 90 glass microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pan European Collaboration on Antipsychotic Naive Schizophrenia (PECANS)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: amisulpride|DRUG: aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Topical Ruxolitinib Evaluation in Immune-related Lichenoid Skin-Toxicities
Status: NOT_YET_RECRUITING
Conditions: Exanthema|Lichenoid Skin Rashes Under Anti-PD1 Tumor Therapy
Interventions: DRUG: Ruxolitinib Topical Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Mobilization Techniques on Balance, Gait, Jumping and Foot Plantar Pressure
Status: COMPLETED
Conditions: Dorsiflexion Deformity of Foot
Interventions: OTHER: Mobilization with movement for Ankle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Adaptive Phase II/III, Two-Part, Double-Blind, Randomized, Placebo-controlled, Dose-Finding, Multi-center Study of the Safety and Efficacy of NaBen®, as an Add-on Therapy With Clozapine, for Residual Symptoms of Refractory Schizophrenia in Adults
Status: RECRUITING
Conditions: Refractory Schizophrenia
Interventions: DRUG: NaBen®|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Therapy vs Arthroscopic Partial Meniscectomy
Status: RECRUITING
Conditions: Knee Medial Meniscus Tears
Interventions: PROCEDURE: physical therapy|PROCEDURE: arthroscopic partial meniscectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Cardiovascular Safety of Insulin Degludec Versus Insulin Glargine in Subjects With Type 2 Diabetes at High Risk of Cardiovascular Events
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dead-space Injecting Equipment Distribution Program for People Who Inject Drugs in Low- and Middle-income Countries
Status: NOT_YET_RECRUITING
Conditions: Drug Use|Hepatitis|Hiv
Interventions: DEVICE: Low dead-space syringes/needles|DEVICE: Hepatitis C Antibody Rapid Diagnostic Test|DEVICE: HIV rapid Diagnostic Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of ALX-0171 in Adult Hematopoietic Stem Cell Transplant (HSCT) Recipients Who Present With Respiratory Syncytial Virus (RSV) Infection
Status: WITHDRAWN
Conditions: Respiratory Syncytial Virus Lower Respiratory Tract Infection
Interventions: BIOLOGICAL: ALX-0171 Dose 1|BIOLOGICAL: ALX-0171 Dose 2|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NAPO - Novel Approach for Oligospermia
Status: NOT_YET_RECRUITING
Conditions: Infertility, Male
Interventions: DRUG: Denosumab|DRUG: sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Construct Validity and Responsiveness of EQ-5D-3L in Patients With Rheumatic Disease
Status: RECRUITING
Conditions: Rheumatoid Arthritis|Polyarthritis|Psoriatic Arthritis|Ankylosing Spondylitis|Rheumatic Diseases
Interventions: OTHER: Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Postoperative Inguinal Pain Between the Onstep Technique and the Lichtenstein Technique
Status: COMPLETED
Conditions: Chronic Pain Post-Procedural
Interventions: PROCEDURE: Lichtenstein Technique|PROCEDURE: Onstep Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Neurobiological Bases of Paternal Nurturance
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Oxytocin|DRUG: Vasopressin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of a Multistrain Probiotic on Cold Symptoms in Healthy Patients With an History of Upper Airways Infection
Status: RECRUITING
Conditions: Cold Symptom
Interventions: DIETARY_SUPPLEMENT: DefensePlus|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Technology Assisted Programs That Promote Mental Health for Teenagers
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Networked Peer Support with Peer Guide|BEHAVIORAL: Networked Peer Support with Clinician Coach
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: German Preoperative Adriamycin Docetaxel Study
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: doxorubicin, docetaxel, tamoxifen|DRUG: doxorubicin, docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DS-9231 in Intermediate-risk (Sub-massive) Acute Pulmonary Embolism (PE)
Status: WITHDRAWN
Conditions: Pulmonary Embolism
Interventions: DRUG: DS-9231|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Systematic Imaging for Follow up of Patients With Ovarian, Fallopian Tube or Primary Peritoneum Cancer
Status: WITHDRAWN
Conditions: Advanced Stage Serous Epithelial Cancer of the Ovary|Advanced Stage Cancer of Tubes|Advanced Stage Cancer of Peritoneum
Interventions: OTHER: Standard strategy|OTHER: Follow-up strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Qudratus Lumborum Block for Postoperative Pain After Endoscopic Prostatectomy.
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Qadratus Lumborum Block|DRUG: 30 milliliters of 0.375% Ropivacaine|DRUG: 30 milliliters of 0.9% NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Double Blinded, Placebo-Controlled Trial of Paliperidone Addition in SRI-Resistant Obsessive-Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: Paliperidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation Combined With Bihemispherictranscranial Direct Current Stimulation in Subacute Ischemic Stroke
Status: UNKNOWN
Conditions: First Ever Clinical Stroke|Ischemic Stroke|Subacute Phase|Persistent Hemiparesis of Upper Extremity
Interventions: PROCEDURE: transcranial direct current stimulation (tDCS)|PROCEDURE: Sham stimulation, then tDCS|PROCEDURE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Reactogenicity, Safety and Immunogenicity of a LAIV А/17/Hong Kong/2017/75108 H7N9 Influenza Vaccine
Status: UNKNOWN
Conditions: Vaccine Adverse Reaction
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: H7N9 LAIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Roles of Prophylactic Subcutaneous Drain in Preventing Surgical Site Infection in Surgical Wound After Abdominal Surgery
Status: NOT_YET_RECRUITING
Conditions: Surgical Site Infection
Interventions: PROCEDURE: Subcutaneous drain|PROCEDURE: No drain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ONC201 in Recurrent or Metastatic Type II Endometrial Cancer Endometrial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Cancer Recurrent
Interventions: DRUG: ONC201
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Both Exercise and Adenosine Stress Testing
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Adenosine SPECT myocardial perfusion imaging|PROCEDURE: Combined adenosine / exercise SPECT myocardial perfusion imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cluster RCT of Embedded Parenting Intervention to Prevent Recurrence and Reduce Impairment in Young Children Exposed to Domestic Violence
Status: UNKNOWN
Conditions: Domestic Violence|Child Abuse
Interventions: BEHAVIORAL: Caring Dads|BEHAVIORAL: Mothers in Mind
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Immunogenicity and Safety of Omicron Variant Vaccines in Comparison With mRNA-1273 Booster Vaccine for COVID-19
Status: COMPLETED
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: mRNA-1273.529|BIOLOGICAL: mRNA-1273|BIOLOGICAL: mRNA-1273.214
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Blocking Extracellular Galectin-3 in Patients With Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: Modified Citrus Pectin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Immunogenicity and Safety of a Recombinant Protein COVID-19 Vaccine SCTV01E-1 in Population Aged Above 18 Years
Status: UNKNOWN
Conditions: COVID-19|SARS-CoV-2 Infection
Interventions: BIOLOGICAL: SCTV01E-1 on D0|BIOLOGICAL: SCTV01E-1 on D28|BIOLOGICAL: SCTV01E-1 on D150|BIOLOGICAL: SCTV01E on D0|BIOLOGICAL: SCTV01E on D28|BIOLOGICAL: SCTV01E on D150|BIOLOGICAL: SCTV01E-1 on D120|BIOLOGICAL: SCTV01E on D120
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect Of Simultaneous Working Length Control Postoperative Pain
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: PROCEDURE: simultaneous working length control using E-CONNECT S|PROCEDURE: separate length determination and root canal preparation using Root ZX apex locator.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Biomarker Signature to Predict the Persistence of Post-traumatic Headache
Status: RECRUITING
Conditions: Post-Traumatic Headache|Healthy
Interventions: DIAGNOSTIC_TEST: Brain Magnetic Resonance Imaging (MRI) Scan|OTHER: Speech Sample|OTHER: Electronic Daily Headache Diary
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preventive Treatment of Oxaliplatin Induced Peripheral Neuropathy in Metastatic Colorectal Cancer (POLAR-M)
Status: TERMINATED
Conditions: Colorectal Cancer|Chemotherapy-induced Peripheral Neuropathy
Interventions: DRUG: Calmangafodipir (2 µmol/kg)|DRUG: Calmangafodipir (5 µmol/kg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Single-arm, Open-label, Clinical Trial of Surufatinib/Serplulimab/Platinum/Etoposide in Neuroendocrine Carcinoma.
Status: NOT_YET_RECRUITING
Conditions: Neuroendocrine Carcinoma
Interventions: DRUG: Surufatinib and Serplulimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Civacir® Polyclonal Immune Globulin (IgG) to Prevent Hepatitis C Virus (HCV) Recurrence in Liver Transplant Patients.
Status: COMPLETED
Conditions: Hepatitis C Infection|Viruses|Hepatocellular Carcinoma|Hepatitis, Viral, Human|Liver Cirrhosis
Interventions: BIOLOGICAL: Civacir® 10%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Memory Consolidation in Pharmacologically Enhanced Naps
Status: COMPLETED
Conditions: Sleep
Interventions: DRUG: zolpidem|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Role of WB-MRI in the Evaluation of Prostate Cancer Patients Treated With Lutetium - Prostate Specific Membrane Antigen (Lu-PSMA)
Status: TERMINATED
Conditions: Metastatic Castration Resistant Prostate Cancer (mCRPC)
Interventions: DIAGNOSTIC_TEST: WB-MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mild Hypofractionation With Proton Therapy or Intensity Modulated Radiation Therapy (IMRT) for Intermediate-Risk Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Adenocarcinoma
Interventions: RADIATION: Proton Therapy|RADIATION: IMRT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Titanium-Nitride-Oxide Coated Bio-Active-Stent (Optimax™) to the Drug (Everolimus) -Eluting Stent (Synergy™) in Acute Coronary Syndrome
Status: UNKNOWN
Conditions: Myocardial Infarction|Percutaneous Coronary Intervention|Atherosclerosis
Interventions: DEVICE: percutaneous coronary intervention|DEVICE: percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing a Digital AEP Risk Intervention With Native Women and Communities Aim 1
Status: RECRUITING
Conditions: Alcohol Exposed Pregnancy|Unplanned Pregnancy|Alcohol Use, Unspecified|Contraception Use|Sexual Behavior
Interventions: BEHAVIORAL: Survey
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dual-tDCS and Anodal PMC tDCS Over the Contralesional Hemisphere on the Upper Limb Function in Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Dual M1-tDCS|DEVICE: a-tDCS over contralesional PMC|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: the Effect of Nutrition-optimized Prehabilitation on Perioperative Intervention in Primary Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: OTHER: Nutritional optimization-led triple prehabilitation Intervention|OTHER: Conventional triple prehabilitation Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurotoxicity Prophylaxis With Intrathecal Dexamethasone and Simvastatin Post Axi-Cel
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma
Interventions: DRUG: Simvastatin|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Motivational Interviewing to Increase Physical Activity Behaviour in Cancer Patients
Status: COMPLETED
Conditions: Cancer, Breast|Cancer of Colon|Endometrial Cancer
Interventions: BEHAVIORAL: Motivational interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Gemcitabine, and Bevacizumab in Treating Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: gemcitabine hydrochloride|DRUG: paclitaxel albumin-stabilized nanoparticle formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga-PSMA HBED-PET/CT in the Evaluation of the Biochemical Relapse in Patients With a History of Prostate Cancer Radically Treated
Status: ACTIVE_NOT_RECRUITING
Conditions: 68Ga-PSMA HBED-PET/CT|Prostate Cancer
Interventions: DRUG: 68Ga- PSMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for the Treatment of Ambulatory Adult and Pediatric Patients With COVID-19
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: casirivimab+imdevimab combination therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: International Study to Determine if AdreView Heart Function Scan Can be Used to Identify Patients With Mild or Moderate Heart Failure (HF) That Benefit From Implanted Medical Device
Status: TERMINATED
Conditions: Heart Failure
Interventions: DRUG: Iobenguane I -123 Injection|DEVICE: Implantable Cardioverter Defibrillator|DRUG: Thyroid blocking|DRUG: Iobenguane I -123 Injection|DEVICE: Implantable Cardioverter Defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Non-invasive Ventilation and High-speed Oxygen Therapy Effects on Heart Function - HiFlow-Heart Study
Status: UNKNOWN
Conditions: Chronic Heart Failure
Interventions: OTHER: HFO/O2C/NIV|OTHER: NIV/O2C/HFO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficiency and Workflow of Femtosecond Laser Assisted Cataract Surgery in a Spanish Public Hospital
Status: COMPLETED
Conditions: Cataract|Cataract Mature|Cataract, Nuclear
Interventions: PROCEDURE: CONVENTIONAL PHACO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Arformoterol Tartrate Inhalation Solution and Racemic Formoterol in Subjects With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Racemic formoterol|DRUG: Arformoterol tartrate inhalation solution|DRUG: Racemic formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simplifying HCV Treatment in Rwanda for Elsewhere in the Developing World: Pangenotypic and Retreatment Study (SHARED3)
Status: UNKNOWN
Conditions: Hepatitis C, Chronic
Interventions: DRUG: sofosbubir/velpatasvir|DRUG: sofosbubir/velpatasvir/voxilaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Everolimus (RAD001) in Metastatic Transitional Cell Carcinoma of the Urothelium
Status: COMPLETED
Conditions: Bladder Cancer|Metastatic Transitional Cell Carcinoma
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Involucrin Has a Role in Verruca Vulgaris? A Clinical and Immunohistochemical Study
Status: COMPLETED
Conditions: Verruca Vulgaris|Involucrin
Interventions: DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Restoring Cognitive Control (ReCon) in Acute Nicotine Withdrawal
Status: COMPLETED
Conditions: Impulse Control Disorders
Interventions: DRUG: SXC-2023|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LinguaFlex Tongue Retractor (LTR) for the Treatment of OSA and Snoring in Adults
Status: ENROLLING_BY_INVITATION
Conditions: Obstructive Sleep Apnea|Snoring
Interventions: DEVICE: LinguaFlex Tongue Retractor (LTR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Naltrexone/Bupropion Cardiovascular Outcomes Study
Status: TERMINATED
Conditions: Obesity|Cardiovascular Diseases
Interventions: DRUG: Naltrexone HCl/Bupropion HCl ER|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utidelone in Combination With AC Versus Docetaxel in Combination With AC for Neoadjuvant Chemotherapy in Patients With HER2-negative Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Utidelone Injection in combination with AC|DRUG: Docetaxel Injection in combination with AC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myocardial Effects of NIV in OHS Patients
Status: COMPLETED
Conditions: Respiratory Failure Chronic|Obesity Hypoventilation Syndrome|Obstructive Sleep Apnea|Cardiac Output, Low
Interventions: PROCEDURE: Noninvasive ventilation volume targetted
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Toripalimab Combined With Chidamide for the Treatment of Relapsed/Refractory Peripheral T-Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: PTCL
Interventions: DRUG: Toripalimab|DRUG: chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Tolerability Study of Pirfenidone in Combination With Sildenafil in Participants With Advanced Idiopathic Pulmonary Fibrosis (IPF) and Intermediate or High Probability of Group 3 Pulmonary Hypertension
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Pirfenidone|DRUG: Placebo|DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Axial Spondyloarthritis With Reduced Doses of NSAIDs
Status: COMPLETED
Conditions: Axial Spondyloarthritis
Interventions: DRUG: Ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of the Chair Lift Test in the Prognostic Evaluation of Pulmonary Embolism: a Single-center Open Prospective Study
Status: NOT_YET_RECRUITING
Conditions: Non-severe Pulmonary Embolism
Interventions: OTHER: chair lift test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: EValuation of the Impact of a TOpical Lotion on Permanent Chemotherapy Induced Hair Disorders in Cancer Survivors
Status: COMPLETED
Conditions: Alopecia
Interventions: OTHER: CG428|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: FOLFOXIRI With or Without Cetuximab as First-line Treatment of Patients With Non-resectable Liver - Only Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: FOLFOXIRI + Cetuximab|DRUG: FOLFOXIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing the Safety of Inter-Hospital Transfer
Status: ACTIVE_NOT_RECRUITING
Conditions: Inpatient Facililty Diagnoses
Interventions: OTHER: New Standardized Accept Note|OTHER: Existing Transfer Patient Admission Process
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study Comparing Esomeprazole and ASA Combined Together as One Capsule Versus These Medications Taken Separately
Status: TERMINATED
Conditions: Peptic Ulcer Disease
Interventions: DRUG: Esomeprazole/ASA Fixed Combination|DRUG: Esomeprazole|DRUG: ASA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Validation Study of the Dx-pH Probe in Children for the Detection of Extra-oesophageal Reflux
Status: COMPLETED
Conditions: Gastro-oesophageal Reflux
Interventions: DEVICE: Experiemental diagnostic procedure: Dx-pH measurement system|OTHER: Peptest assay|OTHER: GORD symptom questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Study of the Magnetic-controlled Capsule Endoscopy Versus Standard Gastroscopy
Status: COMPLETED
Conditions: Gastric Symptoms|Indicated for Upper GI Endoscopy
Interventions: DEVICE: MCE|DEVICE: Standard gastroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Real-time Activity Monitoring to Prevent Admissions During RadioTherapy
Status: COMPLETED
Conditions: Cancer of the Head and Neck|Cancer of Lung|Cancer of Esophagus|Cancer of Stomach
Interventions: OTHER: Enhanced Supportive Care - Status Checks|OTHER: Enhanced Supportive Care - Referrals
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose-Escalation Study of HTX-034 Following Bunionectomy
Status: COMPLETED
Conditions: Bunions
Interventions: DRUG: HTX-034|DRUG: HTX-034|DEVICE: Luer lock applicator|DRUG: Bupivacaine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety, Tolerability and Imaging Characteristics of [68Ga]Ga-DPI-4452 and to Assess Safety, Tolerability, and Efficacy of [177Lu]Lu-DPI-4452 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Clear Cell Renal Cell Cancer (ccRCC)|Pancreatic Ductal Adenocarcinoma (PDAC)|Colorectal Cancer (CRC)
Interventions: DRUG: [68Ga]Ga-DPI-4452|DRUG: [177Lu]Lu-DPI-4452
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Meningococcal Serogroup ACYWX Conjugate Vaccine in Comparison With MenACWY-TT Conjugate Vaccine
Status: ACTIVE_NOT_RECRUITING
Conditions: Meningitis
Interventions: BIOLOGICAL: NmCV-5|BIOLOGICAL: MenACWY-TT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nutritional Intervention to Enhance Sleep Quality and Quantity in Athletes
Status: COMPLETED
Conditions: Sleep|Physical Performance|Cognitive Performance|Balance
Interventions: OTHER: Trypophan, Theanine and 5'AMP|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cell Therapy Associated With Endobronchial Valve
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease Severe
Interventions: DEVICE: Zephyr Endobronchial Valve|BIOLOGICAL: Marrow-derived mesenchymal stromal cell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Intervention Study to Assess the Effect of the Mediterranean Diet on the Plasma Fatty Acid Profile
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: BEHAVIORAL: Intensively advised Mediterranean diet|BEHAVIORAL: usual low-fat dietary advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Value of Pharmacokinetic Assays in the Prediction of Therapeutic Response in Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: PROCEDURE: Blood sample|DEVICE: Rectosigmoidoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Stitch Closure of PFO and Septal Repair
Status: UNKNOWN
Conditions: Foramen Ovale, Patent|Septal Defect, Atrial|Septal Defect, Heart
Interventions: DEVICE: PFO Closure Rate|DEVICE: Published PFO Device Closure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cortical Priming to Optimize Gait Rehabilitation Post Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: tDCS|OTHER: AMT|BEHAVIORAL: Treadmill training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing for COVID-19 in High Risk Children With Intellectual and Developmental Disabilities (COV-IDD)
Status: COMPLETED
Conditions: Covid19
Interventions: DIAGNOSTIC_TEST: COVID-19 RT-PCR test|OTHER: COVID-19 Vaccine Education Campaign
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Transcranial Magnetic Stimulation (TMS) for Trigeminal Neuralgia
Status: UNKNOWN
Conditions: Facial Pain
Interventions: DEVICE: TMS|DEVICE: sham TMS coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Modified Immune Cells (CD19/CD20 CAR-T Cells) in Treating Patients With Recurrent or Refractory B-Cell Lymphoma or Chronic Lymphocytic Leukemia
Status: RECRUITING
Conditions: CD19 Positive|CD20 Positive|Recurrent Chronic Lymphocytic Leukemia|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Diffuse Large B-Cell Lymphoma|Refractory Follicular Lymphoma|Refractory Mantle Cell Lymphoma|Refractory Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma|Refractory Small Lymphocytic Lymphoma
Interventions: BIOLOGICAL: Chimeric Antigen Receptor T-Cell Therapy|DRUG: Cyclophosphamide|DRUG: Fludarabine Phosphate|BIOLOGICAL: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interventions for the Wellbeing of Students at the University of Helsinki
Status: RECRUITING
Conditions: Well-Being, Psychological
Interventions: BEHAVIORAL: Groups 4 Health (G4H)|BEHAVIORAL: The study psychologists' group intervention|BEHAVIORAL: Towards better well-being and studying -online course
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prolonged Exposure Therapy for Post Traumatic Stress Disorder Following Sexual Assault
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Prolonged Exposure (PE)|BEHAVIORAL: Treatment as usual group therapy (TUGT)|BEHAVIORAL: Supportive counseling (SC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Clinical Safety and Efficacy of Limbal Stem Cell for Treatment of Superficial Corneal Pathologies".
Status: UNKNOWN
Conditions: Corneal Scars and Opacities
Interventions: BIOLOGICAL: Ex-vivo cultivated Allogeneic limbal stromal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simultaneaous Detection of Quantitative Somatic Alterations Using the Qantitative Multiplex Pcr of Short Fluorescent Fragments Method (QMPSF) in Stage II-III Colon Cancer: a Prospective Study
Status: COMPLETED
Conditions: Colorectal Cancer|Stage II and III
Interventions: GENETIC: evaluation of the recurrence rate according to molecular analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Comparison of Efficacy of Dexamethasone and Methylprednisolone in Moderate to Severe Covid 19 Disease
Status: COMPLETED
Conditions: Covid 19 Disease
Interventions: DRUG: Dexamethasone 2 MG/ML|DRUG: Methylprednisolone Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weaning of Nasal Continuous Positive Airway Pressure (CPAP) in Premature Infants
Status: COMPLETED
Conditions: Prematurity|Respiratory Distress Syndrome, Infant
Interventions: PROCEDURE: Sudden wean of nasal CPAP|PROCEDURE: Gradual wean of nasal CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TACE Combined With Sintilimab and Bevacizumab for Unresectable HCC
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma Non-resectable
Interventions: DRUG: TACE combined with sintilimab and bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Thoracolumbar Spine Fractures: Percutaneously Placed Pedicle Screws Versus Open Treatment
Status: WITHDRAWN
Conditions: Thoracolumbar Spine Trauma
Interventions: PROCEDURE: Percutaneous Pedicle Screw Fixation|PROCEDURE: Open Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Prosthetic Disc Replacement
Status: TERMINATED
Conditions: Lumbar Degenerative Disc Disease|Cervical Degenerative Disc Disease|Kyphosis
Interventions: PROCEDURE: Arthrodesis|DEVICE: Arthroplasty (PRODISC-C® , PRODISC-L®, Mobi-C®, Mobidisc®, PrestigeLP®, A-Mav®, O-Mav®, DISCOCERV®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Intermittent Fasting and Behavioral Economics Intervention on Weight Control in Obese Patients
Status: ENROLLING_BY_INVITATION
Conditions: Intermittent Fasting|Weight Loss|Behavioral Economic|Obese|HOMA-IR
Interventions: BEHAVIORAL: Intermittent fasting|BEHAVIORAL: Intermittent fasting + Behavioral economic|BEHAVIORAL: Intensive Lifestyle Modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gamma Secretase Inhibitor RO4929097 in Previously Treated Metastatic Pancreas Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Pancreas|Recurrent Pancreatic Cancer|Stage IV Pancreatic Cancer
Interventions: DRUG: gamma-secretase/Notch signalling pathway inhibitor RO4929097
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Immunotherapy for Hematological Malignancies by Selective Depletion of Regulatory T Cells
Status: RECRUITING
Conditions: Hematological Malignancies|Regulatory T Cell Depletion|Relapse
Interventions: PROCEDURE: T-reg depleted DLI|PROCEDURE: Standard DLI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SELUTION 4 De Novo Small Vessel IDE Trial
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: PCI with SELUTION SLR DCB|DEVICE: PCI with FDA approved "-limus" DES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Gemigliptin or Acarbose on Endothelial Function in Type 2 DM Patients
Status: UNKNOWN
Conditions: Endothelial Function|Type 2 Diabetes|Gemigliptin|Acarbose
Interventions: DRUG: Gemigliptin|DRUG: Acarbose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT