pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Fatty Acid Supplementation in Children With ASD
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: LCPUFA Oil Supplement|DIETARY_SUPPLEMENT: Canola Oil Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TMS Measures of Plasticity and Excitatory/Inhibitory Ratio as Biomarkers: R-baclofen Effects in Normal Volunteers
Status: TERMINATED
Conditions: Autism
Interventions: DRUG: R-baclofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Prehabilitation in Oncology Via Exercise- Bone Marrow Transplant
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplant|Hematologic Diseases|Physical Activity|Prehabilitation
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Prehabilitation Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ASSESSMENT OF TRISTETRAPROLIN EXPRESSION IN LESIONAL SKIN OF PATIENTS WITH NON SEGMENTAL VITILIGO
Status: NOT_YET_RECRUITING
Conditions: Non-segmental Vitiligo
Interventions: DIAGNOSTIC_TEST: skin biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Investigate the Efficacy and Safety of Sofosbuvir/Velpatasvir (SOF/VEL) Fixed-Dose Combination (FDC) and Sofosbuvir/Velpatasvir/Voxilaprevir (SOF/VEL/VOX ) FDC for 12 Weeks in Adults With Chronic Hepatitis C Virus (HCV) Infection
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: SOF/VEL|DRUG: SOF/VEL/VOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of 400mcg Versus 800mcg Buccal Misoprostol Following Mifepristone 200mg for Abortion up to 63 Days Gestation
Status: COMPLETED
Conditions: Induced Abortion
Interventions: DRUG: Mifepristone, misoprostol|DRUG: mifepristone, misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid to Prevent Heavy Bleeding After Childbirth in Women at Higher Risk
Status: RECRUITING
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Tranexamic acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pain Control of Thoracoscopic Major Pulmonary Resection
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Pre-emptive bupivacaine wound infiltration|PROCEDURE: intravenous patient controlled analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Sublingual Sufentanil on Postoperative Pain and Analgesic Requirements in Spine Surgery Patients
Status: UNKNOWN
Conditions: Spine Fusion|Pain, Postoperative|Opioid Use
Interventions: DRUG: Sublingual Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensified Acute Kidney Disease Care to Reduce Chronic Kidney Disease
Status: UNKNOWN
Conditions: Acute Kidney Injury|Renal Insufficiency, Chronic|Acute Kidney Disease|Decision Support Systems, Clinical
Interventions: BEHAVIORAL: Multidisciplinary team (MDT) care and Acute kidney disease (AKD) clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Assess Intraocular Pressure and Ocular Safety of the Beta-3 Agonist Mirabegron in Research Subjects
Status: COMPLETED
Conditions: Intraocular Pressure
Interventions: DRUG: Mirabegron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Assessment of the Safety and Performance of Elbow Supports in the Context of Epicondylitis or a Return to Sport After Sprain
Status: RECRUITING
Conditions: Epicondylitis|Elbow Sprain
Interventions: DEVICE: Elbow MID 500|OTHER: Control group Elbow MID 500|DEVICE: Elbow STRAP|OTHER: Control group Elbow STRAP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Tech and High Touch (HT2): Transforming Patient Engagement Through Portal Technology at the Bedside
Status: COMPLETED
Conditions: Physician-Patient Relations|Inpatient Facility Diagnoses|Electronic Health Records|Outpatient
Interventions: OTHER: High Touch|OTHER: Low Touch|OTHER: High Tech|OTHER: Low Tech
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Treatment of MB07133 Plus Sintilimab in Patients With Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Safety Issues|Efficacy|MTD
Interventions: DRUG: Sintilimab 200mg+MB07133 600mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Infiltration Analgesia With Ropivacaine Versus Placebo in Bilateral Hip Arthroplasty
Status: UNKNOWN
Conditions: Postoperative Pain|Hip Arthroplasty
Interventions: DRUG: ropivacaine 0,2%|DRUG: saline.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optic Nerve Sheath Diameter Difference Between Different Injection Volume
Status: COMPLETED
Conditions: Optic Nerve Sheath Diameter
Interventions: PROCEDURE: thoracic epidural catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel, Carboplatin Plus Bevacizumab in Pretreated, Advanced or Metastatic Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Carboplatin|DRUG: Bevacizumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Evaluation of Resin Endocrown as Long Term Interim Restoration Versus Stainless Steel Crown for Endodontically Treated First Permanent Molar in Children: Randomized Controlled Pilot Study.
Status: COMPLETED
Conditions: Dental Caries in Children
Interventions: OTHER: Endocrown "composite".
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasonography in the Diagnosis of Nasal Fractures
Status: RECRUITING
Conditions: Nasal Bone Fracture|Nasal Injury|Facial Injuries|Nasal Deformity, Acquired|Nose; Wound
Interventions: DIAGNOSTIC_TEST: Nasal Ultrasonography|DIAGNOSTIC_TEST: Computed Tomography Scan of the Face
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preoperative Versus Postoperative Quadratous Lunborum Block in Nephrectomy
Status: NOT_YET_RECRUITING
Conditions: Regional Blocks|Renal Surgery
Interventions: OTHER: quadratous lumborum block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cytokine Induced Killer (CIK) Cells In Leukemia Patients
Status: COMPLETED
Conditions: Hematologic Malignancies
Interventions: BIOLOGICAL: in vitro expanded Cytokine Induced Killer (CIK) cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mean Platelet Volume and STEMI Clinical Risk Scores in Prediction of Impaired Myocardial Perfusion In Acute STEMI Patients Undergoing Primary Percutaneous Coronary Intervention.
Status: COMPLETED
Conditions: No-Reflow Phenomenon
Interventions: OTHER: Mean platelet volume, lymphocyte number, STEMI clinical risk scores
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase II Study of Paclitaxel and Carboplatin in Patients With an Elevated-Risk Cancer of the Uterus
Status: TERMINATED
Conditions: Uterine Cancer
Interventions: DRUG: Paclitaxel and carboplatin combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Beams as an Adjunct to Reperfusion Therapy in STEMI
Status: UNKNOWN
Conditions: Myocardial Infarction|ST Elevation Myocardial Infarction
Interventions: OTHER: Ultrasound beams Philips HD11 XE®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Adjunctive Intracoronary Streptokinase on Late Term Left Ventricular Infarct Size and Volumes in Patients With Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Coronary Syndromes|Acute Myocardial Infarction|Reperfusion Injury
Interventions: DRUG: Streptokinase|PROCEDURE: primary percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mifepristone on the Expression of Cervical Prostaglandin EP3 Receptors
Status: TERMINATED
Conditions: Cervical Prostaglandin EP3 Receptors|Pregnancy
Interventions: DRUG: Mifepristone|OTHER: Non-treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of ZILRETTA Versus CELESTONE on Quality of Life, Pain, Neuromuscular Function, and Physical Performance
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Triamcinolone acetonide extended-release injectable suspension|DRUG: Betamethasone sodium phosphate and betamethasone acetate Injectable Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate ITCA 650 Compared to Sitagliptin for the Treatment of Type 2 Diabetes
Status: WITHDRAWN
Conditions: Type 2 Diabetes
Interventions: DRUG: ITCA 650 60 mcg/day|DRUG: sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tramadol Versus Diclofenac for Reducing Pain Before Outpatient Hysteroscopy in Post Menopausal Women
Status: UNKNOWN
Conditions: Hysteroscopy|Pain
Interventions: DRUG: Diclofenac|DRUG: Tramadol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of a Tissue Selective Estrogen Complex (TSEC) on Depression and the Neural Reward System in the Perimenopause"
Status: COMPLETED
Conditions: Perimenopausal Disorder|Depression
Interventions: DRUG: Bazedoxifene/Conjugated Estrogen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of HSY244 in Participants With Atrial Fibrillation
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: DRUG: HSY244|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Adding Cetuximab to Chemotherapy for the Treatment of Advanced and/or Recurrent Cervical Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Cancer
Interventions: DRUG: paclitaxel|DRUG: carboplatin|DRUG: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic PB103 (NK Cells) Therapy in Non-small Cell Lung Cancer (NSCLC) Patients
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: donor-derived NK cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Mild Hypobaric Hypoxia on Oxygen Saturation During Sleep
Status: COMPLETED
Conditions: Sleep-related Respiratory Disturbance
Interventions: OTHER: Reduced barometric pressure|OTHER: Sea level equivalent barometric pressure|OTHER: Reduced barometric pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluate the Efficacy of Insulin Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Human Insulin Inhalation Powder|DRUG: Injectable insulin|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Comparison of Educational Effectiveness Between FAST and STROKE 112 in Yunlin Community
Status: UNKNOWN
Conditions: Stroke, Cardiovascular
Interventions: OTHER: stroke educational campaign: FAST|OTHER: stroke educational campaign: STROKE 112
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Venous Pressure Measurement of the Great Saphenous Vein Using Controlled Compression Ultrasound in Healthy Persons and Patients With Chronic Venous Disease as a New Non Invasive Method for Investigation of the Pathophysiology in Primary Varicose Veins
Status: UNKNOWN
Conditions: Chronic Venous Insufficiency
Interventions: PROCEDURE: Ultrasound (venous pressure measurement)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of GDC-0941 in Participants With Locally Advanced or Metastatic Solid Tumors for Which Standard Therapy Either Does Not Exist or Has Proven Ineffective or Intolerable
Status: COMPLETED
Conditions: Solid Cancers
Interventions: DRUG: GDC-0941
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow Transplant Plus Cyclophosphamide and Total-Body Irradiation in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: filgrastim|BIOLOGICAL: sargramostim|BIOLOGICAL: therapeutic immune globulin|DRUG: cyclophosphamide|DRUG: methotrexate|DRUG: tacrolimus|PROCEDURE: allogeneic bone marrow transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation, Immunotherapy and PARP Inhibitor in Triple Negative Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Triple Negative Breast Cancer
Interventions: DRUG: Niraparib|DRUG: Dostarlimab|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gender Differences in Social Cognition in Patients With Schizophrenia of Recent Diagnosis and Healthy Controls Subjects
Status: COMPLETED
Conditions: Women With Recent Diagnosis of Schizophrenia|Men With Recent Diagnosis of Schizophrenia|Healthy Women|Healthy Men
Interventions: OTHER: GENDER
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Robot-assisted Rehabilitation of the Upper Limb in Acute and Subacute Post-stroke Patients
Status: COMPLETED
Conditions: Stroke|Cerebrovascular Accident|Upper Extremity Paresis
Interventions: DEVICE: Robot therapy (NeReBot)|OTHER: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SAVE Trial - Use of the Selution Sirolimus Eluting Balloon for Dysfunctional AV accEss Treatment Indications
Status: ACTIVE_NOT_RECRUITING
Conditions: AV Fistula
Interventions: DEVICE: SELUTION SLR™ DEB|DEVICE: Control Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mass Balance and Absolute Bioavailability Study of RO7049389 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: [12C] RO7049389|DRUG: [13C] RO7049389|DRUG: [14C] RO7049389
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Tanespimycin in Treating Women With Refractory Locally Advanced or Metastatic Breast Cancer
Status: TERMINATED
Conditions: Recurrent Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: tanespimycin|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Walking Ankle Robot for Foot Drop in Aging and Disabled Populations: A Demonstration Project
Status: NOT_YET_RECRUITING
Conditions: Foot Drop|Peripheral Nervous System Diseases|Gait Disorders, Neurologic|Mobility Limitation
Interventions: DEVICE: Treadmill Ankle Robot Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Pembrolizumab Therapy With Timing and Intensification With Axitinib
Status: WITHDRAWN
Conditions: Renal Cell Cancer
Interventions: DRUG: Axitinib|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This Clinical Study is to Test Efficacy and Safety of BT595 in Chronic Primary Immune Thrombocytopenia (ITP)
Status: COMPLETED
Conditions: Immune Thrombocytopenia
Interventions: BIOLOGICAL: BT595
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Kisspeptin Glucose-Stimulated Insulin Secretion With Oral Glucose Tolerance Test
Status: COMPLETED
Conditions: Metabolic Diseases
Interventions: DIAGNOSTIC_TEST: Oral Glucose Tolerance Test|DRUG: Kisspeptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Relative Bioavailability Study Between Two Formulations Containing Ambroxol Hydrochloride
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ambroxol hydrochloride soft pastille|DRUG: Mucosolvan ® adult syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selumetinib in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Promyelocytic Leukemia (M3)|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Recurrent Adult Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia
Interventions: DRUG: selumetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthy Aging Through Dietary Intervention
Status: COMPLETED
Conditions: Aging, Healthy
Interventions: DRUG: Flavanol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Effectiveness of 5A-5R Counselling Services for Tobacco Cessation
Status: ENROLLING_BY_INVITATION
Conditions: Tobacco Use Cessation
Interventions: BEHAVIORAL: 5A-5R-based counselling session|BEHAVIORAL: Counseling through mobile phone call and text message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: An Individualised Treatment vs. a Minimal Program in Women With Late-term Shoulder Impairments After Breast Cancer.
Status: COMPLETED
Conditions: Shoulder Pain|Late Effect|Breast Cancer|Rehabilitation
Interventions: OTHER: The expert assessment of shoulder impairments and individualised treatment plan|OTHER: A minimal physiotherapeutic rehabilitation program delivered in a pamphlet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate 5-ALA Combined With CV01 Delivery of Ultrasound in Recurrent High Grade Glioma
Status: ACTIVE_NOT_RECRUITING
Conditions: High Grade Glioma
Interventions: DRUG: 5 Aminolevulinic Acid|DEVICE: CV01-delivered ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Narcotic vs. Non-narcotic Pain Study Protocol
Status: COMPLETED
Conditions: Carpal Tunnel
Interventions: DRUG: Narcotic|DRUG: non-narcotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prehabilitation Versus Enhanced Recovery Program for Elective Colorectal Cancer Surgery.
Status: COMPLETED
Conditions: Colorectal Cancer|Insulin Resistance
Interventions: PROCEDURE: Prehabilitation + ERAS|PROCEDURE: ERAS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Drug Interaction and Safety Between Valsartan and Rosuvastatin in Healthy Male Volunteers
Status: COMPLETED
Conditions: Hypertension, Hyperlipidemia
Interventions: DRUG: Sequence 1 : Period 1(V) Period 2(R) Period 3(V+R)|DRUG: Sequence 2 : Period 1(V+R) Period 2(V) Period 3(R)|DRUG: Sequence 3 : Period 1(R) Period 2(V+R) Period 3(V)|DRUG: Sequence 4 : Period 1(V+R) Period 2(R) Period 3(V)|DRUG: Sequence 5 : Period 1(R) Period 2(V) Period 3(V+R)|DRUG: Sequence 6 : Period 1(V) Period 2(V+R) Period 3(R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness and Safety of Three Protocols Usin Li-ESWT for Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: OTHER: Low-intensity extracorporeal shock wave therapy (Li-ESWT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Prophylactic TPO Combined With BMS-IMRT to Esophageal Cancer Patients
Status: RECRUITING
Conditions: Esophageal Cancer|Intensity-modulated Radiation Therapy|Concurrent Chemoradiotherapy|Thrombocytopenia
Interventions: DRUG: rhTPO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of Radical Right Hemicolectomy Versus Radical Right Hemicolectomy Combined With Indocyanine Green Fluorescence Imaging Lymphatic Tracer Dissection for the Treatment of Right Colon Cancer
Status: RECRUITING
Conditions: Colon Cancer
Interventions: PROCEDURE: radical right hemicolectomy combined with indocyanine green fluorescence imaging lymphatic tracer dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Motor Rehabilitation Treatment on Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: PROCEDURE: Standard motor rehabilitation treatment|PROCEDURE: Intensive motor rehabilitation treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multisensory Stimulation in Infants for Eye Examination
Status: COMPLETED
Conditions: Premature Retinopathy|Pain, Eye
Interventions: BEHAVIORAL: Multisensorial Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Nursing Interventions on Adherence to Treatment With Anti-tuberculosis Drugs in Children and Adolescents
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BEHAVIORAL: Leaflet written in the patient's/family mother tongue|BEHAVIORAL: A follow-up telephone call|BIOLOGICAL: Eidus-Hamilton Test|BEHAVIORAL: A written questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intrabronchial Voriconazole Instillation for Inoperable Pulmonary Aspergilloma
Status: UNKNOWN
Conditions: Aspergilloma
Interventions: DRUG: Intrabronchial Voriconazole instillation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Lofexidine to Prevent Stress-Related Opiate Relapse During Naltrexone Treatment - 1
Status: COMPLETED
Conditions: Opioid-Related Disorders
Interventions: DRUG: Lofexidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Medicine for Wound Care Procedures
Status: COMPLETED
Conditions: Wound Care|Pain Intensity|Hyperalgesia|Nausea|Vomiting|Hallucinations
Interventions: DRUG: Morphine plus Ketamine|DRUG: Morphine plus Saline (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nurse-initiated Conversations for Early Integration of Palliative Care in Pediatric Oncology
Status: RECRUITING
Conditions: Solid Tumor|Hematological Malignancies
Interventions: BEHAVIORAL: NiCE|OTHER: Routine PPC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Monoclonal Antibody Therapy and Chemotherapy in Treating Patients With Acute Promyelocytic Leukemia in Remission
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: lintuzumab|DRUG: cytarabine|DRUG: idarubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: HVLAT, Electric DN, Exercise Vs. Mobilization, STM, Exercise, TENS for Tension Type Headaches
Status: RECRUITING
Conditions: Tension-Type Headache
Interventions: OTHER: Thrust Manipulation, Electric Dry Needling and Exercise|OTHER: Non-thrust Mobilization, Soft-Tissue Mobilization, Exercise and TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of SBRT Compared With Conventional Radiotherapy for Oligometastatic Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: NSCLC
Interventions: RADIATION: Conventional Fractionated Radiotherapy|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fields Of Effects Of Two Commercial Preparations Of Botulinum Toxin Type A At Equal Labeled Unit Doses
Status: COMPLETED
Conditions: Skin Wrinkling
Interventions: DRUG: AbobotulinumtoxinA (ABO)|DRUG: OnabotulinumtoxinA (ONA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Pembrolizumab and Afatinib in Patients With Non-small Cell Lung Cancer With Resistance to Erlotinib
Status: COMPLETED
Conditions: Recurrent Non-Small Cell Lung Carcinoma|Stage IIIA Non-Small Cell Lung Cancer|Stage IIIB Non-Small Cell Lung Cancer|Stage IV Non-Small Cell Lung Cancer
Interventions: DRUG: Afatinib Dimaleate|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Near-Infrared Spectroscopy for Pediatric Acute Scrotum and Testicular Torsion
Status: COMPLETED
Conditions: Acute Scrotum|Testicular Torsion
Interventions: DEVICE: Hutchison Technologies Inspectra StO2 SpotCheck Near-Infrared Spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating the Efficacy of Ragweed-SPIRE Following Exposure to Ragweed Allergen in an Environmental Exposure Chamber
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: BIOLOGICAL: Ragweed-SPIRE|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of OSTEOFORM (rhPTH [1-34]) in Increasing Bone Mineral Density in Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Osteoform|DRUG: SHELCAL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antithrombotic Therapy in Patients Undergoing CIED Surgery - HEMATOMA NO MORE Registry
Status: COMPLETED
Conditions: Device Related Infection|Antithrombotic Drugs|Cardiac Arrhythmia|Surgery--Complications|Hematoma
Interventions: OTHER: CIED surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Serum Resistin Level Following Non-surgical Periodontal Therapy in Diabetic Patients With Chronic Periodontitis
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: PROCEDURE: non-surgical periodontal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of Subcutaneous (SC) Lebrikizumab Administered by Needle and Syringe or by Prefilled Syringe With Needle Safety Device (PFS-NSD)
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Lebrikizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Temperature Monitoring for tHe Early Recognition of Febrile Neutropenia in Haematological MALignancies
Status: UNKNOWN
Conditions: Haematological Malignancy|Leukemia|Lymphoma|Myeloma|Temperature Change, Body
Interventions: DEVICE: TempTraq temperature monitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Determine Safety & Recommended Phase 2 Dosing of Zeaxanthin Alone or in Combination w/Pembrolizumab in Patients With Metastatic Cancer
Status: RECRUITING
Conditions: Cancer Metastatic|Metastatic Solid Tumor
Interventions: BIOLOGICAL: Zeaxanthin|COMBINATION_PRODUCT: Zeaxanthin Plus Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fish Oil and Adaptations to Resistance Exercise in Older People
Status: COMPLETED
Conditions: Ageing
Interventions: BEHAVIORAL: Resistance Exercise Training|DIETARY_SUPPLEMENT: Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serum and Exhaled Breath Condensate MALDI-MS of Lung Cancer. (SPORE)
Status: TERMINATED
Conditions: Lung Cancer
Interventions: GENETIC: protein expression analysis|GENETIC: proteomic profiling|OTHER: biologic sample preservation procedure|OTHER: laboratory biomarker analysis|OTHER: matrix-asst laser desorption/ionization time flight mass spectrometry|OTHER: questionnaire administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Tolerability of Topical Rossoseq™ Compared to Vehicle in Rosacea Subtype 1 (Erythematotelangiectatic)
Status: COMPLETED
Conditions: Rosacea Subtype 1 (Erythematotelangiectatic)
Interventions: DEVICE: Rossoseq™|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SBRT Combined With Osimertinib Compared With Osimertinib for Stage IV NSCLC
Status: NOT_YET_RECRUITING
Conditions: Stage IV Non-small Cell Lung Cancer
Interventions: RADIATION: SBRT+Osimertinib|DRUG: Osimertinib 80 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Redsenol-1 Plus on Cancer-related Fatigue in Adults
Status: RECRUITING
Conditions: Fatigue|Cancer, Treatment-Related
Interventions: DIETARY_SUPPLEMENT: Redsenol-1 Plus|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Common Mental Disorders in Women in Mozambique by Addressing Intimate Partner Violence in Couples
Status: NOT_YET_RECRUITING
Conditions: Depression|Anxiety|PTSD|Intimate Partner Violence
Interventions: BEHAVIORAL: Interpersonal Psychotherapy for Couples|BEHAVIORAL: Interpersonal Psychotherapy (Individual)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Posterior Tibial Nerve Stimulation for Treatment of Chronic Anal Fissure
Status: COMPLETED
Conditions: Chronic Anal Fissure
Interventions: PROCEDURE: lateral internal sphincterotomy|PROCEDURE: TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Different Antiplatelet Preparations for an Unruptured Intracranial Aneurysm
Status: COMPLETED
Conditions: Aneurysm, Cerebral|Endovascular Procedures
Interventions: DRUG: Aspirin|DRUG: Prasugrel|DRUG: Clopidogrel|DRUG: Cilostazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of IABP Early Insertion on Mortality in Post Cardiac Arrest Patients With Acute Coronary Syndrome
Status: UNKNOWN
Conditions: Post-Cardiac Arrest Syndrome
Interventions: DEVICE: Intra Aortic Balloon Pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Computer Guided Versus Conventional Ridge Splitting of Horizontal Deficient in Maxillary Anterior Alveolar Ridge
Status: UNKNOWN
Conditions: Ridge Deficency
Interventions: PROCEDURE: Computer guided surgical cutting guide|PROCEDURE: Conventional alveolar ridge splitting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Behavioral Therapy Versus Interferential Current on Bladder Dysfunction in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Bladder Dysfunction on Patients With Multiple Sclerosis
Interventions: DEVICE: biofeedback training and interferential therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leukocyte and Platelet-rich Fibrin (L-PRF) Effects on Alveolar Ridge Preservation. A Randomized Controlled Clinical Trial.
Status: ACTIVE_NOT_RECRUITING
Conditions: Alveolar Ridge Preservation|Dental Implants
Interventions: PROCEDURE: Tooth extraction|PROCEDURE: Alveolar ridge preservation with L-PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect Lactate Administration on Cerebral Blood Flow During Hypoglycemia
Status: UNKNOWN
Conditions: Type1diabetes|Hypoglycemia Unawareness
Interventions: DRUG: Sodium Lactate|DRUG: Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Does Sexual Intercourse Affect the Outcomes of Frozen-thawed Embryo Transfer?
Status: RECRUITING
Conditions: Embryo Transfer|Fertilization in Vitro|Coitus
Interventions: BEHAVIORAL: Sexual intercourse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Hyperthermic Intraperitoneal Chemotherapy With Cisplatin During Surgery or Cisplatin Before Surgery for the Treatment of Stage III or IV Ovarian, Fallopian Tube or Peritoneal Cancer
Status: RECRUITING
Conditions: Fallopian Tube Endometrioid Adenocarcinoma|Fallopian Tube Mucinous Adenocarcinoma|Fallopian Tube Serous Adenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mucinous Adenocarcinoma|Ovarian Serous Adenocarcinoma|Primary Peritoneal Endometrioid Adenocarcinoma|Primary Peritoneal Serous Adenocarcinoma|Stage III Fallopian Tube Cancer AJCC v8|Stage III Ovarian Cancer AJCC v8|Stage III Primary Peritoneal Cancer AJCC v8|Stage IIIA Fallopian Tube Cancer AJCC v8|Stage IIIA Ovarian Cancer AJCC v8|Stage IIIA Primary Peritoneal Cancer AJCC v8|Stage IIIA1 Fallopian Tube Cancer AJCC v8|Stage IIIA1 Ovarian Cancer AJCC v8|Stage IIIA2 Fallopian Tube Cancer AJCC v8|Stage IIIA2 Ovarian Cancer AJCC v8|Stage IIIB Fallopian Tube Cancer AJCC v8|Stage IIIB Ovarian Cancer AJCC v8|Stage IIIB Primary Peritoneal Cancer AJCC v8|Stage IIIC Fallopian Tube Cancer AJCC v8|Stage IIIC Ovarian Cancer AJCC v8|Stage IIIC Primary Peritoneal Cancer AJCC v8|Stage IV Fallopian Tube Cancer AJCC v8|Stage IV Ovarian Cancer AJCC v8|Stage IV Primary Peritoneal Cancer AJCC v8|Stage IVA Fallopian Tube Cancer AJCC v8|Stage IVA Ovarian Cancer AJCC v8|Stage IVA Primary Peritoneal Cancer AJCC v8|Stage IVB Fallopian Tube Cancer AJCC v8|Stage IVB Ovarian Cancer AJCC v8|Stage IVB Primary Peritoneal Cancer AJCC v8
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|PROCEDURE: Cytoreductive Surgery|DRUG: Hyperthermic Intraperitoneal Chemotherapy|DRUG: Paclitaxel|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Stereotactic Radiotherapy With Bevacizumab in the Treatment of Recurrent Malignant Glioma
Status: COMPLETED
Conditions: Brain Cancer|MALIGNANT GLIOMA|Glioblastoma|Anaplastic Astrocytoma (AA)|Anaplastic Oligodendroglioma (AO)|Anaplastic Oligo-astrocytoma (AOA)|Anaplastic Mixed Gliomas|Malignant Glioma NOS
Interventions: OTHER: Bevacizumab & Stereotactic Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Perioperative Optimisation to the Hip Arthroplasty Outcomes
Status: COMPLETED
Conditions: Hip Osteoarthritis
Interventions: PROCEDURE: Semi-closed loop infusion system tactic.|PROCEDURE: Routine infusion therapy tactic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 99mTc-rhAnnexin V-128: a First In Man Study in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Adult Volunteers
Interventions: DRUG: Kit for the Preparation of 99mTc-rhAnnexin V-128
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Two Fragmentation Modalities in Femtosecond Laser-assisted Cataract Surgery
Status: TERMINATED
Conditions: Cataract
Interventions: DEVICE: nuclear lens fragmentation in 8 pieces|DEVICE: nuclear lens fragmentation in 16 pieces
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: F18PET/CT Versus TC-MDP Scanning to Detect Bone Mets
Status: UNKNOWN
Conditions: Bone Metastases
Interventions: DEVICE: Bone Scan: F18-Fluoride PET/CT or TC-MDP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Telmisartan Versus Amlodipine in Patients With Mild-to-Moderate Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan|DEVICE: Amlodipine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhanced Liver Function in Non-alcoholic Obese Fatty Liver Patients by Low Level Laser Therapy
Status: COMPLETED
Conditions: Fatty Liver, Nonalcoholic|Liver Function
Interventions: DEVICE: low level laser|OTHER: Mediterranean diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Withdrawal of Immunosuppression and Donor Lymphocyte Infusions Following Allogeneic Transplant for Pediatric Hematologic Malignancies
Status: COMPLETED
Conditions: Acute Leukemia|Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Biphenotypic Leukemia|Pre-leukemic Syndromes|Monosomy 7|Bone Marrow Clonal Malformations|Juvenile Myelomonocytic Leukemia|Myelodysplastic Syndromes|Chronic Myelogenous Leukemia
Interventions: OTHER: Withdrawal of immunosuppression and donor lymphocyte infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stability of the Cochlear Baha BI300/BA400 Implant System Loaded From 1 Week Post-surgery
Status: COMPLETED
Conditions: Hearing Loss - Conductive
Interventions: PROCEDURE: One week loading of Bone Anchored Hearing Aid (BAHA)|DEVICE: Cochlear Baha BI300/BA400 Implant System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Intervention of Multi-vitamin With Minerals to Hyperuricemia
Status: UNKNOWN
Conditions: Hyperuricemia
Interventions: COMBINATION_PRODUCT: High-dose multi-vitamins with minerals|COMBINATION_PRODUCT: Low-dose multi-vitamins with minerals|COMBINATION_PRODUCT: Hypouricemic tablets|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tai Chi on Balance, Mood, Cognition, and Quality of Life in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: "Tai-chi" - a special program for patients with multiple sclerosis - once a week training with a Tai Chi instructor lasting 90 minutes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transcranial Direct Current Stimulation (tDCS) in Post-Stroke Working Memory Deficits
Status: TERMINATED
Conditions: Stroke|Cognitive Deficit|Cognitive Impairment|Short-Term Memory Impairment
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rapamycin as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD): The Role of Biomarkers in Predicting a Response to Therapy
Status: TERMINATED
Conditions: Autosomal Dominant Polycystic Kidney Disease
Interventions: DRUG: Rapamycin|OTHER: Standard of Care-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Replacement in Statin-Induced Myopathy
Status: WITHDRAWN
Conditions: HMG COA Reductase Inhibitor Adverse Reaction
Interventions: DRUG: Vitamin D (Cholecalciferol )|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Study of Postoperative Rotator Cuff Repair Rehabilitation
Status: COMPLETED
Conditions: Full Thickness Rotator Cuff Tear
Interventions: PROCEDURE: Postoperative Jackins Exercise Protocol|PROCEDURE: Postoperative Pulleys Exercise Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-escalation Trial of Anti-C5aR Antibody in Healthy Subjects
Status: COMPLETED
Conditions: Inflammation|Systemic Lupus Erythematosus|Rheumatoid Arthritis|Healthy
Interventions: DRUG: NNC 0151-0000-0000|DRUG: NNC 0151-0000-0000|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraarticular Platelet-rich Plasma Injections Versus Corticosteroid Injections in Primary Knee Osteoarthritis
Status: WITHDRAWN
Conditions: Osteoarthritis
Interventions: DRUG: Intra-articular platelet-rich plasma|DRUG: Intra-articular corticosteroid injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT