pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Calorie Restriction on Accumulation of Old, Modified Proteins in Abdominally Obese Adults
Status: COMPLETED
Conditions: Insulin Resistance
Interventions: BEHAVIORAL: Calorie Restriction|BEHAVIORAL: Control (normal living)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Resting Full-cycle Flow Ratio (RFR) Versus Angiography to Guide Revascularization Strategy in Patients Undergoing Coronary Artery By-pass Grafting (CABG)
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: RFR guided CABG|PROCEDURE: Angio guided CABG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Selenium to Improve Neurological Outcome After Cardiac Arrest
Status: WITHDRAWN
Conditions: Cardiac Arrest
Interventions: DRUG: Sodium-selenite|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Frequenting a Social Leg Program on Therapeutic Adherence and Venous Leg Ulcer Wound Healing Outcomes
Status: NOT_YET_RECRUITING
Conditions: Venous Leg Ulcer|Social Interaction
Interventions: OTHER: Social leg program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacist Assisted Medication Program Enhancing the Regulation of Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Pharmacist collaboration in diabetes care|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Efficacy and Safety of X0002 Spray in Subjects With Osteoarthritis Knee Pain
Status: COMPLETED
Conditions: Pain Associated With Osteoarthritis of the Knee
Interventions: DRUG: X0002
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Elixir Medical Clinical Evaluation of the DESolve Myolimus Eluting Bioresorbable Coronary Stent System - DESolve I Trial
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: DESolve Novolimus Eluting Bioresorbable Coronary Scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Virtual Reality Application on Pain Due to Fistula Puncture in Hemodialysis Patients
Status: COMPLETED
Conditions: Chronic Kidney Diseases
Interventions: OTHER: virtual reality application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Atomoxetine and Placebo in Children With Attention-Deficit/Hyperactivity Disorder (ADHD) and/or Reading Disorder (RD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Reading Disorder
Interventions: DRUG: Atomoxetine Hydrochloride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Automated Extracranial Internal Carotid Artery Ultrasound Sensor for Traumatic Brain Injury
Status: WITHDRAWN
Conditions: Traumatic Brain Injury
Interventions: DEVICE: Automated extracranial internal carotid artery ultrasound sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Exercises on Convergence Insufficiency in Individuals With Temporomandibular Disorders
Status: RECRUITING
Conditions: Temporomandibular Disorder|Temporomandibular Joint Disorders|Temporomandibular Joint Dysfunction Syndrome|Convergence Insufficiency
Interventions: OTHER: Oculomotor Therapy|OTHER: Therapy for Temporomandibular Disorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Third-generation TKIs Combined With Azacitidine and Bcl-2 Inhibitor in Patients With CML-MBP
Status: NOT_YET_RECRUITING
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Ponatinib|DRUG: Azacitidine|DRUG: Venetoclax|DRUG: Olverembatinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating the Analgesic Efficacy of Capsaicin 8% Patches in Chronic Coccygodynia.
Status: RECRUITING
Conditions: Coccyx Disorder|Neuropathic Pain|Coccygodynia
Interventions: DRUG: Capsaicin 179 Mg Cutaneous Patch|DRUG: Capsaicin low concentration patch (capsaicin 0,04%, 3,2 mg/cm2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-VEGF Therapy for Acute Thyroid Eye Disease
Status: RECRUITING
Conditions: Thyroid Eye Disease
Interventions: DRUG: Sub-tenon injection of saline followed by a sub-tenon injection of aflibercept|DRUG: Sub-tenon injection of hyaluronidase (HA) followed by a sub-tenon injection of aflibercept|DRUG: Sub-tenon injection of hyaluronidase (HA) alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Alternative Schedule of Velcade/Dexamethasone Plus Doxil for Patients With Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: bortezomib|DRUG: dexamethasone|DRUG: doxorubicin HCl liposome
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Ultra-High-Dose Hypofractionated or Single-Dose Radiotherapy for Intermediate Risk Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: IGRT 45 Gy in 5 fractions of 9 Gy|RADIATION: IGRT 24 Gy single dose|DRUG: Dexamethasone|DRUG: Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EFFECTIVENESS, SAFETY AND IMMUNOGENICITY OF THE HALF DOSE OF THE VACCINE ChadOx1 nCoV-19 (AZD1222) for COVID-19
Status: UNKNOWN
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: Half dose of ChAdOx1 nCoV-19 (AZD1222)|BIOLOGICAL: Standard dose of ChAdOx1 nCoV-19 (AZD1222)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of CC 486 (Oral Azacitidine) Plus BSC as Maintenance After sc Azacitidine in Elderly HR-IPSS-R MDS Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: MDS|CMML
Interventions: DRUG: CC-486
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-Time-in-Humans Study to Assess Safety, Pharmacokinetics & Pharmacodynamics of SB756050
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: SB-756050 immediate release capsule|DRUG: SB-756050 modified release capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Talazoparib and Radiation Therapy in Treating Patients With Locally Recurrent Gynecologic Cancers
Status: RECRUITING
Conditions: Malignant Female Reproductive System Neoplasm|Recurrent Cervical Carcinoma|Recurrent Endometrial Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Recurrent Vaginal Carcinoma|Stage IV Cervical Cancer AJCC v8|Stage IV Fallopian Tube Cancer AJCC v8|Stage IV Ovarian Cancer AJCC v8|Stage IV Primary Peritoneal Cancer AJCC v8|Stage IV Uterine Corpus Cancer AJCC v8|Stage IV Vaginal Cancer AJCC v8|Stage IVA Cervical Cancer AJCC v8|Stage IVA Fallopian Tube Cancer AJCC v8|Stage IVA Ovarian Cancer AJCC v8|Stage IVA Primary Peritoneal Cancer AJCC v8|Stage IVA Uterine Corpus Cancer AJCC v8|Stage IVA Vaginal Cancer AJCC v8|Stage IVB Cervical Cancer AJCC v8|Stage IVB Fallopian Tube Cancer AJCC v8|Stage IVB Ovarian Cancer AJCC v8|Stage IVB Primary Peritoneal Cancer AJCC v8|Stage IVB Uterine Corpus Cancer AJCC v8|Stage IVB Vaginal Cancer AJCC v8
Interventions: OTHER: Quality-of-Life Assessment|RADIATION: Radiation Therapy|DRUG: Talazoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BCG in Combination With Durvalumab in Adult BCG-naïve, High-risk NMIBC Participants
Status: RECRUITING
Conditions: Non-Muscle- Invasive Bladder Cancer
Interventions: BIOLOGICAL: Durvalumab|BIOLOGICAL: BCG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Absorb Bioresorbable Scaffold vs. Drug Coated Balloon for Treatment Of In-Stent-Restenosis
Status: UNKNOWN
Conditions: In-stent Restenosis
Interventions: PROCEDURE: Sequent Please inflation|PROCEDURE: Absorb BVS implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: National Multicenter Interventional Study Aimed at Evaluating the Effect on the Intestinal Microbiota in Chronically Frail Patients Who Share Alterations in Intestinal Function.
Status: COMPLETED
Conditions: Adhd|ALS|Bronchial Asthma
Interventions: DIETARY_SUPPLEMENT: Prebiotic fiber|DIETARY_SUPPLEMENT: Dietary fiber|DIETARY_SUPPLEMENT: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough
Status: COMPLETED
Conditions: Refractory Chronic Cough
Interventions: DRUG: BLU-5937|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy and Retifanlimab in Patients With Selected Sarcomas (TORNADO)
Status: RECRUITING
Conditions: Resectable Sarcoma
Interventions: DRUG: Doxorubicin|DRUG: Ifosfamide|DRUG: INCMGA00012
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Value of Tranxemic Acid to Reduce Intraoperative Blood Loss During Elective Cesarean Sections in High Risk Women
Status: COMPLETED
Conditions: Intraoperative Bleeding
Interventions: DRUG: Tranexamic Acid|PROCEDURE: Cesarean section
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Continuous Transversus Abdominis Plane (TAP) Catheters on Postoperative Pain After Renal Transplantation
Status: TERMINATED
Conditions: Pain
Interventions: OTHER: TAP catheter with Ropivicaine|OTHER: Fentanyl IV PCA and placebo TAP catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Tramadol With Levobupivacaine for Modified Pectoral Nerve Block
Status: COMPLETED
Conditions: Breast Cancer|Radical Mastectomy Surgery
Interventions: DRUG: Levobupivacaine|DRUG: Levobupivacaine and Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Addition of a Pectoserratus Block to Interscalene Block in Patients Undergoing Total Shoulder Replacement
Status: RECRUITING
Conditions: Total Shoulder Arthroplasty
Interventions: DRUG: bupivacaine.|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Recurrent Ovarian CarcinoSarcoma Anti-pd-1 Niraparib
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Carcinosarcoma|Endometrial Carcinosarcoma
Interventions: DRUG: Niraparib|COMBINATION_PRODUCT: Niraparib + TSR-042 (Dostarlimab)|DRUG: Chemotherapy Drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modifying Factors in Striated Muscle Laminopathies
Status: RECRUITING
Conditions: Laminopathies|Emery Dreifuss Muscular Dystrophy 2|LMNA-Related Congenital Muscular Dystrophy|Dilated Cardiomyopathy-1A
Interventions: PROCEDURE: Skin Biopsy|PROCEDURE: Muscle biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Robotic Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy for Treatment of Gastric Cancer With Limited Peritoneal Metastasis, ROBO-CHIP Study
Status: RECRUITING
Conditions: Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma|Metastatic Malignant Neoplasm in the Peritoneum
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Cisplatin|PROCEDURE: Computed Tomography|DRUG: Docetaxel|PROCEDURE: Gastrectomy|DRUG: Hyperthermic Intraperitoneal Chemotherapy|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Machine Learning Assisted Recognition of Out-of-Hospital Cardiac Arrest During Emergency Calls.
Status: COMPLETED
Conditions: Out-Of-Hospital Cardiac Arrest
Interventions: OTHER: Alert on dispatchers screen 'Suspect cardiac arrest'
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prediction of NEC With Urinary iFABP
Status: WITHDRAWN
Conditions: Prematurity|Necrotizing Enterocolitis
Interventions: OTHER: Assessment of urinary iFABP|OTHER: Administration of enteral feedings
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Relationship Between Contrast Media Volume and Tube Voltage in CT for Optimal Liver Enhancement, Based on Body Weight.
Status: COMPLETED
Conditions: Radiation|Contrast Media|Liver|Body Weight
Interventions: RADIATION: Radiation dose reduction|OTHER: Contrast media volume reduction|RADIATION: Unenhanced slice|DIAGNOSTIC_TEST: Weight
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pralatrexate and Docetaxel in Treating Patients With Stage IV Esophageal or Gastroesophageal Cancer Who Have Failed Platinum-Based Therapy
Status: COMPLETED
Conditions: Adenocarcinoma of the Esophagus|Adenocarcinomas of the Gastroesophageal Junction|Recurrent Esophageal Cancer|Squamous Cell Carcinoma of the Esophagus|Stage IV Esophageal Cancer
Interventions: DRUG: pralatrexate|DRUG: docetaxel|RADIATION: fludeoxyglucose F 18|PROCEDURE: positron emission tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of X-ray, Acetabular Guides and CT in THR
Status: COMPLETED
Conditions: Total Hip Replacement
Interventions: DEVICE: Corin OPS™|OTHER: 2D X-ray templating technology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Randomised Placebo-controlled Duloxetine-referenced Study of Efficacy and Safety of 15 and 20 mg of Vortioxetine (Lu AA21004) in Acute Treatment of Major Depressive Disorder in Adults
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Placebo|DRUG: Vortioxetine (Lu AA21004)|DRUG: Duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for Patient With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DRUG: Duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RTX-240 Monotherapy and in Combination With Pembrolizumab
Status: TERMINATED
Conditions: Solid Tumor, AML Adult
Interventions: DRUG: RTX-240|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Application of Chlorhexidine to the Umbilical Cord for Prevention of Omphalitis and Neonatal Mortality in Rural District of Pakistan
Status: COMPLETED
Conditions: Omphalitis
Interventions: DRUG: 4% Chlorhexidine|OTHER: Hand washing Soap|DRUG: 4% Chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Impact of Intravesical Gemcitabine and 1/3 Dose Bacillus Calmette-Guerin on the Quality of Life in Superficial Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: Gemcitabine 2 g|DRUG: BCG Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: An Exploratory Clinical Study on Autophagy and Multi-level Molecular Profiling During Spermidine Supplementation
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression|Healthy
Interventions: DIETARY_SUPPLEMENT: Spermidine (spermidineLIFE ®) OR Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Use in Pediatric Procedures
Status: COMPLETED
Conditions: Oxygen Deficiency|Desaturation of Blood|Hypoventilation|Anesthesia; Adverse Effect
Interventions: DEVICE: High-flow nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Efficacy and Safety of JW0201 Added on in Patients With T2DM
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: JW0201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-87801493 in Combination With T-Cell Engagers in Participants With B-cell Non-Hodgkin Lymphoid (NHLs) Cancer
Status: RECRUITING
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: JNJ-87801493|DRUG: JNJ-80948543|DRUG: JNJ-75348780
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Four Cycles Versus Six Cycles of Cisplatin-based Chemotherapy in Metastatic Urothelial Carcinoma
Status: UNKNOWN
Conditions: Bladder Cancer|Ureter Cancer|Urethral Cancer|Transitional Cell Carcinoma
Interventions: DRUG: Treatment duration of cisplatin based chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nordic Randomized Trial on Laparoscopic Versus Vaginal Cerclage
Status: RECRUITING
Conditions: Preterm Birth|Cervical Insufficiency
Interventions: PROCEDURE: Laparoscopic cerclage|PROCEDURE: Vaginal cerclage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: MLC1501 Study Assessing Efficacy in STROke Recovery
Status: NOT_YET_RECRUITING
Conditions: Stroke|Stroke, Ischemic|Strokes Thrombotic|Stroke Sequelae|Stroke, Cardiovascular|Stroke, Embolic|Stroke, Cryptogenic
Interventions: DRUG: MLC1501|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy, Cetuximab and Radiation for Patients With Localized Gastric Cancer
Status: TERMINATED
Conditions: Gastric Cancer
Interventions: BIOLOGICAL: Cetuximab|DRUG: Capecitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Skin Care Protocols for Facial Resurfacing
Status: COMPLETED
Conditions: Facial Photo Damage|Periocular Fine Wrinkles|Perioral Fine Wrinkles
Interventions: OTHER: Obagi New-Derm System|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Bioequivalence Study of Ribavirin in Healthy Adult Subjects Under Fed Condition
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Ribavirin 400 mg film coated tablet (1*400mg)|DRUG: Copegus® 200 mg film coated tablet (2*200mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Investigation for the Foldax Tria Aortic Heart Valve- India
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Valve Stenosis|Aortic Valve Insufficiency|Aortic Valve Calcification|Aortic Valve Disease
Interventions: DEVICE: Foldax Tria Aortic Valve
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychophysiologic Predictors of Post-deployment Mental Health Outcomes
Status: COMPLETED
Conditions: Post-traumatic Stress Disorder
Interventions: DEVICE: heart rate variability biofeedback|DEVICE: Cognitive bias modification training|DEVICE: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Lutein in S-26 Gold On Growth And Safety
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Lutein fortification|OTHER: Standard formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: RCT: Triple vs Sequential vs Concomitant Therapy H Pylori
Status: COMPLETED
Conditions: Bacterial Infection Due to Helicobacter Pylori (H. Pylori)
Interventions: DRUG: 10 day triple therapy|DRUG: 10 day sequential therapy|DRUG: 10 day concomitant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Various Adipokines and Vascular Inflammation Measured by Positron Emission Tomography (PET) With 18F-fluoro-deoxyglucose (FDG) (18FDG-PET)
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: OTHER: Cross sectional study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Activity and Safety of Everolimus+Octreotide LAR+Metformin in Advanced Pancreatic Well-differentiated NETs
Status: UNKNOWN
Conditions: Well Differentiated Pancreatic Endocrine Tumor
Interventions: DRUG: Everolimus plus Octreotide LAR plus Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Quality of Life of Terminal Ileitis Patients With Crohn's Disease Treated With Anti-TNF or Surgical Resection
Status: WITHDRAWN
Conditions: Quality of Life
Interventions: DRUG: Anti TNF|PROCEDURE: ileocecal resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Simultaneous Integrated Boost Radiotherapy and Concurrent Nimotuzumab or Chemotherapy for Esophageal Carcinoma
Status: UNKNOWN
Conditions: Esophageal Neoplasms
Interventions: RADIATION: IMRT simultaneous integrated boost|DRUG: Nimotuzumab|DRUG: Paclitaxel|DRUG: Nedaplatin|PROCEDURE: Esophagectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase IIa Study Assessing the Effects of AZD1236 on Biomarkers in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: AZD1236|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Maternally Scent-digested Blanket on Stress, Crying and Physiological Parameters of Premature Newborns
Status: RECRUITING
Conditions: Family-centered Care
Interventions: BEHAVIORAL: A blanket impregnated with the mother's odor|BEHAVIORAL: blanket without mother's smell|BEHAVIORAL: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Study Evaluating the Efficacy and Safety of KX-826
Status: COMPLETED
Conditions: Androgenetic Alopecia (AGA)
Interventions: DRUG: KX-826-2.5 mg (0.25%)/60 mL BID|DRUG: KX-826-5 mg (5%)/60 mL QD|DRUG: KX-826-5 mg (5%)/60 mL BID|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Establish Diagnostic and Prognostic Models for Preclinical AD Patients Based on Multimodal MRI, Behavioral, Genetic, and Plasma Biomarkers
Status: RECRUITING
Conditions: Alzheimer Disease, Late Onset|Mild Cognitive Impairment|Subjective Cognitive Decline
Interventions: OTHER: Multimodal magnetic resonance imaging scanning, behavioral, genetic and plasma biomarker testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CaP Cement is Equivalent to Iliac Bone Graft in Filling of Large Metaphyseal Defects
Status: COMPLETED
Conditions: Dorsal Malunion of the Distal Radius
Interventions: PROCEDURE: corrective osteotomy distal radius
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inflammatory Response Conventional Total Knee Replacement Versus Mako Total Knee Replacement
Status: COMPLETED
Conditions: Knee Osteoarthritis|Arthritis|Surgery
Interventions: DEVICE: Total Knee Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of a Warmed Surgical Bandage System on Subcutaneous Tissue Oxygen Tension After Cardiac Surgery
Status: TERMINATED
Conditions: Cardiac Surgery
Interventions: DEVICE: conventional bandage|DEVICE: warming bandage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Compare the Efficacy and Safety of Idecabtagene Vicleucel With Lenalidomide Maintenance Therapy Versus Lenalidomide Maintenance Therapy Alone in Adult Participants With Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Autologous Stem Cell Transplantation
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: idecabtagene vicleucel|DRUG: Lenalidomide|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of NY-ESO-1 ISCOMATRIX® in Patients With Measurable Stage III or IV Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: NY-ESO-1 ISCOMATRIX® vaccine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Analgesia in Painful Diabetic Neuropathy
Status: WITHDRAWN
Conditions: Diabetic Neuropathy Peripheral|Neuropathic Pain|Diabetic Foot Infection
Interventions: PROCEDURE: Continuous peripheral nerve blocks|PROCEDURE: Analgesic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neurodegenerative Alzheimer's Disease and Amyotrophic Lateral Sclerosis (NADALS) Basket Trial
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis|Alzheimer Disease|Mild Cognitive Impairment
Interventions: DRUG: Baricitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Flow Anesthesia Without Initial High Flow Phase
Status: COMPLETED
Conditions: Low Flow Anesthesia|Volatile Anesthetic Consumption
Interventions: PROCEDURE: Conventional Low flow Anesthesia|PROCEDURE: Low Flow Anesthesia with fixed fresh gas flow rate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Influence of Stabilization Splint Thickness on The Temporomandibular Disorders
Status: COMPLETED
Conditions: Temporomandibular Disorder|Temporomandibular Joint Disorders|Orofacial Pain
Interventions: OTHER: stabilization splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Pharmacokinetics of GSK1278863 in Subjects With End Stage Renal Disease Undergoing Peritoneal Dialysis
Status: COMPLETED
Conditions: Anaemia
Interventions: DRUG: GSK1278863
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Relative Bioavailability Study of 200mg/5 mL Azithromycin Oral Suspension Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Azithromycin|DRUG: Zithromax®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: HPV Vaccine Intervention for Young Sexual Minority Men
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Subject
Interventions: OTHER: Best Practice|OTHER: Informational Intervention|OTHER: Questionnaire Administration|BEHAVIORAL: Text Message-Based Intervention|BEHAVIORAL: Text Message-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Benefits of R Anastomotic Technique for Billroth-Ⅱ Reconstruction With Braun Anastomosis After Totally Laparoscopic Distal Gastrectomy
Status: COMPLETED
Conditions: Time for R Anastomosis; Complication Related to Anastomosis
Interventions: PROCEDURE: R anastomosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Short-term Clinical Performance of Multifocal Soft Contact Lens
Status: ACTIVE_NOT_RECRUITING
Conditions: Myopia
Interventions: DEVICE: MiSight mutifocal soft contact lens|DEVICE: Proclear 1 Day soft contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy, Radiation Therapy, and Bone Marrow Transplantation in Treating Patients With Retinoblastoma
Status: COMPLETED
Conditions: Retinoblastoma
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: topotecan hydrochloride|PROCEDURE: autologous bone marrow transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Hydrogen-Oxygen Generator With Nebulizer for Adjuvant Treatment of Novel Coronavirus Disease 2019 (COVID-19)
Status: NOT_YET_RECRUITING
Conditions: Covid19|Hydrogen-oxygen Gas|AMS-H-03
Interventions: DEVICE: Hydrogen-Oxygen Generator with Nebulizer, AMS-H-03|DEVICE: OLO-1 Medical Molecular Sieve Oxygen Generator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Effect of 1.5 Versus 3% NaCl on Brain Relaxation and Microcirculation
Status: COMPLETED
Conditions: Brain Tumors
Interventions: PROCEDURE: 1.5% NaCl|PROCEDURE: 3% NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concomitant or Sequential Phlebectomy After Endovenous Laser Therapy for Varicose Veins
Status: COMPLETED
Conditions: Varicose Veins|Endovenous Laser Ablation|Phlebectomies
Interventions: PROCEDURE: Endovenous Laser ablation and concomitant phlebectomies|PROCEDURE: Endovenous Laser ablation and sequential phlebectomies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of the Chin Cup on Temporomandibular Joint and Mandibular Dimensions
Status: COMPLETED
Conditions: Class III Malocclusion
Interventions: DEVICE: Chincup|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Angiogenic Imaging in Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension|Exercise Associated Pulmonary Arterial Hypertension
Interventions: DIAGNOSTIC_TEST: PET-CT Imaging with [89Zr]-bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Identification of Predictive Neuroinflammatory Biomarkers of Neuro-radiological Evolution in Severe Traumatic Brain Injury
Status: UNKNOWN
Conditions: Severe Traumatic Brain Injury
Interventions: BIOLOGICAL: Biological Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Direct-from-blood Bacterial Testing on Antibiotic Administration and Clinical Outcomes
Status: RECRUITING
Conditions: Bloodstream Infection|Sepsis Bacterial|MRSA Bacteremia|Vancomycin
Interventions: OTHER: T2Bacteria® Panel (direct-from-blood testing)|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Testosterone Replacement to Alleviate Pain in Postmenopausal Women (TRAPP Trial)
Status: RECRUITING
Conditions: Pain|Opioid Use|Androgen Deficiency
Interventions: DRUG: Testosterone Cypionate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Growth Hormone Releasing Hormone in Reducing Abdominal Fat in People Who Are Obese
Status: COMPLETED
Conditions: Abdominal Obesity|Growth Hormone Deficiency
Interventions: DRUG: Growth hormone releasing hormone (GHRH) 1-44|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhalation of Corticosteroids in Smoking and Non-smoking Asthmatics.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: 100 micrograms Fluticasone propionate|DRUG: 500 micrograms Fluticasone propionate|DRUG: lactose powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Rabeprazole Extended Release 50 mg Versus Ranitidine 150 mg for Maintenance of Healed Erosive Gastroesophageal Reflux Disease (GERD)
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: DRUG: Rabeprazole ER|DRUG: Ranitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Efficacy and Safety of Dermalax Implant Plus
Status: COMPLETED
Conditions: Correction of Nasolabial Folds
Interventions: DEVICE: Dermalax Implant Plus|DEVICE: Restylane Sub-Q
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EXPAREL Administered Into the TAP for Analgesia in Subjects Undergoing Open Total Abdominal Hysterectomy
Status: TERMINATED
Conditions: Postoperative Pain
Interventions: DRUG: EXPAREL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab in Patients With Severe Covid-19
Status: RECRUITING
Conditions: COVID-19 Pneumonia
Interventions: DRUG: Bevacizumab|OTHER: Placebo|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TREAT-SC: Early, Short Course Oral Dexamethasone for the Treatment of Sydenham Chorea in Children
Status: NOT_YET_RECRUITING
Conditions: Rheumatic Fever|Sydenham Chorea
Interventions: DRUG: Dexamethasone Oral|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Assess The Effect Of PF-04531083 On Heat Pain In Healthy Volunteers With Ultraviolet Light Sensitized Skin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-04531083 100mg|DRUG: PF-04531083 2000mg|DRUG: Placebo suspension|DRUG: Placebo tablet|DRUG: Oxycodone 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prednisone-Placebo vs Prednisone-Valacyclovir in Bell´s Palsy
Status: COMPLETED
Conditions: Bell´s Palsy
Interventions: DRUG: prednisone- valacyclovir|DRUG: prednisone-placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dronaderone to Prevent Recurrent Implantable Cardioverter Defibrillator (ICD) Shocks
Status: UNKNOWN
Conditions: ICD|ICD SHOCKS|DRONEDARONE
Interventions: DRUG: Dronedarone arm|DRUG: Dronedarone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet-delivered Trauma-focused Cognitive-behavioral Therapy as an Early Intervention After Sexual Trauma
Status: NOT_YET_RECRUITING
Conditions: Acute Stress Disorder|Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: Condensed Internet delivered prolonged exposure (CIPE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess PDM608 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: PDM608|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sound Healing for Anxiety: A Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Mental Health Issue|Anxiety Generalized|Anxiety State
Interventions: OTHER: Biofield tuning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Arterial Hypertension Quality Enhancement Research Initiative Extension Program
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: observational study with patients treated with Tracleer, Ventavis, Veletri, Opsumit and/or Uptravi
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Eltrombopag+hATG+CsA vs. hATG+CsA in Children With Severe AA
Status: UNKNOWN
Conditions: Acquired Aplastic Anemia
Interventions: DRUG: Eltrombopag|DRUG: IST (ATG + CsA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral QLT091001 in Retinitis Pigmentosa (RP) Subjects With an Autosomal Dominant Mutation in Retinal Pigment Epithelial 65 Protein (RPE65)
Status: COMPLETED
Conditions: Retinitis Pigmentosa (RP)
Interventions: DRUG: QLT091001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Two Anti-HIV Drug Regimens for Youth Who Have Failed Prior Therapy
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Abacavir sulfate|DRUG: Emtricitabine|DRUG: Lamivudine|DRUG: Lopinavir/ritonavir|DRUG: Saquinavir|DRUG: Tenofovir disoproxil fumarate|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flexofytol® for the Treatment of Endometriosis- Associated Pain
Status: UNKNOWN
Conditions: Endometriosis
Interventions: DIETARY_SUPPLEMENT: Flexofytol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Second Meal Effects of a Wholegrain Cereal Product on Blood Glucose Response
Status: COMPLETED
Conditions: Blood Glucose Response
Interventions: OTHER: Reference Product|OTHER: Wholegrain product Dose A|OTHER: Wholegrain product Dose B|OTHER: Wholegrain product Dose A, cut kernels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Immunology and Safety of Maternal RSV Vaccination (ABRYSVO), Infant Nirsevimab (BEYFORTUS) Immunization, or Both Products
Status: NOT_YET_RECRUITING
Conditions: Respiratory Syncytial Virus Infection
Interventions: BIOLOGICAL: Abrysvo|BIOLOGICAL: Beyfortus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Concurrent Chemoradiotherapy With Weekly Cisplatin Versus Concurrent Chemoradiotherapy With Weekly Cisplatin and Paclitaxel in Locally Advanced Carcinoma Cervix
Status: UNKNOWN
Conditions: Carcinoma Cervix
Interventions: DRUG: Paclitaxel, Cisplatin|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of BNC210 in PTSD
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: DRUG: BNC210|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Motivational Interview Based Discharge Planning for Patients With Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: BEHAVIORAL: a discharge planning using the strategy of motivational interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Noninvasive Early Detection of Lung Allograft Dysfunction After Lung Transplantation With Multiple Breath Washout Test
Status: RECRUITING
Conditions: Chronic Rejection of Lung Transplant
Interventions: DEVICE: Multiple Breath Washout (MBW) tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Evaluation of the Post Operative Sensitivity of Cention-N(Commercially Available Restorative Material) Using Conventional and Polymer Bur- In-vivo Study
Status: UNKNOWN
Conditions: Dental Caries|Dentin Sensitivity
Interventions: DEVICE: Class 1 cavity preparation using conventional steel bur and restoration with Cention-n(commercially available restorative material).|DEVICE: Class 1 cavity preparation using polymer bur and restoration with Cention-n(commercially available restorative material).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Mesenchymal Stem Cells in Primary Sclerosing Cholangitis
Status: UNKNOWN
Conditions: Primary Sclerosing Cholangitis
Interventions: DRUG: UCMSC|DRUG: UDCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Biopsies of Abdominal Subcutaneous Fat to Study the Role of the Activation of Endocannabinoid 1 Receptors (CB1R) on Adipocyte Glucolipid Metabolism
Status: COMPLETED
Conditions: Hernia Surgery
Interventions: PROCEDURE: Samples of adipose tissue
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pomalidomide in Treating Patients With Kaposi Sarcoma and Human Immunodeficiency Virus Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Immunodeficiency Virus 1 Positive|Skin Kaposi Sarcoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT