pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of the Effect of Vemurafenib on the Pharmacokinetics of Phenprocoumon in Patients With BRAFV600 Mutation-Positive Metastatic Malignancy
Status: COMPLETED
Conditions: Malignant Melanoma, Neoplasms
Interventions: DRUG: phenprocoumon|DRUG: vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study of Safety, Reactogenicity and Immunogenicity of HRV Vaccine in HIV Infected Infants in South Africa
Status: COMPLETED
Conditions: Infections, Rotavirus
Interventions: BIOLOGICAL: Rotarix|BIOLOGICAL: Placebo|BIOLOGICAL: Tritanrix-HB+Hib|BIOLOGICAL: Polio Sabin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Additional Effects of Triamcinolone to Hyaluronic Acid on Knee Osteoarthritis
Status: UNKNOWN
Conditions: Physical Activity|Functional Performance
Interventions: DRUG: Triamcinolone|DEVICE: Hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Training for Mood and Anxiety Disorders
Status: COMPLETED
Conditions: Major Depressive Disorder|Depression|Bipolar Disorder|Post-traumatic Stress Disorder|Generalized Anxiety Disorder|Social Phobia
Interventions: BEHAVIORAL: emotional memory training exercise|BEHAVIORAL: memory training exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can Ultrasound Replace Computed Tomography (CT) Scan in Those Unable to Have Computed Tomography (CT) Contrast Agents
Status: COMPLETED
Conditions: Nephrotoxicity of CT Contrast Agents|CT Scans in Those With Renal Compromise|Sensitivity to CT Contrast Agents|US With CEUS as Replacement for Unenhanced CT Scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Application of New Technologies in the Resection of Intracranial Tumors
Status: UNKNOWN
Conditions: Intracranial Neoplasm
Interventions: DEVICE: intraoperative neuronavigation ultrasound, intraoperative tractography, intraoperative fluorescence, advanced neuronavigation and intraoperative neurophysiology
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Hemodynamics Between Dexmedetomidine and Propofol for Sedation in Patients With Abdominal Surgery
Status: COMPLETED
Conditions: Disorder; Mental, Sedative|Pain, Postoperative|Surgery
Interventions: DRUG: Propofol|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparision of IPACK and Periarticular Block With Adductor Block Alone After Total Knee Artroplasty
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: PROCEDURE: block|PROCEDURE: adductor canal block|PROCEDURE: Adductor Canal Block plus IPACK Block|PROCEDURE: adductor Canal Block plus PAI Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Which is the Best Bedside Test to Detect Endobronchial Intubation?
Status: COMPLETED
Conditions: Endobronchial Intubation
Interventions: OTHER: Auscultation|OTHER: Observation of symmetric chest movements|OTHER: Tube depth|OTHER: All three
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Endotracheal Tube Cuff Inflation Pressure Varieties and Response to Education Among Anesthetists
Status: COMPLETED
Conditions: Endotracheal Tube
Interventions: BEHAVIORAL: Before the education program|BEHAVIORAL: After the education program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study on the Phenomenon of Remote Ischaemic Preconditioning in Patients With Peripheral Artery Disease
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: OTHER: Repeated remote ischemic preconditioning|OTHER: Simulation of repeated remote ischemic preconditioning (sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine Optimum Intravenous Starting Dose of MIRCERA for Treatment of Pediatric Participants With Anemia and Chronic Kidney Disease on Hemodialysis
Status: COMPLETED
Conditions: Renal Anemia
Interventions: DRUG: Methoxy Polyethylene Glycol-Epoetin Beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial of Atezolizumab and Interleukin-12 Gene Therapy in Metastatic Non-Small Cell Lung Cancer With Progression on First-Line Immunotherapy With or Without Chemotherapy
Status: SUSPENDED
Conditions: Non-small Cell Lung Cancer
Interventions: COMBINATION_PRODUCT: Atezolizumab and Interleukin-12 Gene Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Catheter Study: Central Venous Catheter Survival in Cancer Patients Using Low Molecular Weight Heparin (Dalteparin) for the Treatment of Deep Vein Thrombosis
Status: COMPLETED
Conditions: Embolism and Thrombosis
Interventions: DRUG: Dalteparin|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FitJoints: Getting Fit for Hip and Knee Replacement
Status: RECRUITING
Conditions: Hip Osteoarthritis|Knee Osteoarthritis
Interventions: OTHER: FitJoints Multi-modal Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of High Density Lipoprotein Cholesterol (HDL-C)-Raising Mechanism of Rosuvastatin (CRESTOR™) by Quantifying the Key Steps of Reverse Cholesterol Transport (RCT)
Status: COMPLETED
Conditions: Metabolic Syndrome|Dyslipidemia
Interventions: DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Comparison of UnderwateR Versus Regular Coagulation in Endoscopic Submucosal DissectioN and Third Space Endoscopy
Status: RECRUITING
Conditions: Gastrointestinal Diseases|Endoscopic Surgery
Interventions: PROCEDURE: Coventional coagulation|PROCEDURE: Underwater coagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resistance Training in Patients With Chronic Obstructive Lung Disease (COPD): Whole Body Vibration Versus Conventional Resistance Training
Status: COMPLETED
Conditions: COPD
Interventions: BEHAVIORAL: Conventional resistance training program|BEHAVIORAL: Whole body vibration resistance training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BPA vs. PEA in CTEPH
Status: RECRUITING
Conditions: Chronic Thromboembolic Pulmonary Hypertension
Interventions: PROCEDURE: Pulmonary endarterectomy|PROCEDURE: Balloon pulmonary angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Mirabegron From Bladogra 25 mg Extended Release Tablets (Multi-Apex for Pharmaceutical Industries, Egypt) Versus Myrbetriq 25 mg Extended Release Tablets (Marketed by Astellas Pharma US, Inc, Product of Japan)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Bladogra|DRUG: Myrbetriq (first dosing)|DRUG: Myrbetriq (second dosing)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CRP for Respiratory Diagnosis in Kyrgyz Pediatric Practice
Status: COMPLETED
Conditions: Antibiotic Resistance|Respiratory Tract Infections|Pediatric Infectious Disease|CRP
Interventions: DIAGNOSTIC_TEST: CRP POCT (C-reactive protein point of care test)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nitrous Oxide as Treatment for Fibromyalgia
Status: RECRUITING
Conditions: Fibromyalgia|Central Neuropathic Pain
Interventions: DRUG: Nitrous oxide gas for inhalation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Expressions of TRPV1 in Airway of Asthmatics
Status: WITHDRAWN
Conditions: Moderate Persistent Asthma|Severe Persistent Asthma|Nodule Solitary Pulmonary|Pulmonary Atelectasis
Interventions: PROCEDURE: Bronchial biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: ECT-Pembrolizumab in Patients With Unresectable Melanoma With Superficial or Superficial and Visceral Metastases
Status: RECRUITING
Conditions: Malignant Melanoma
Interventions: COMBINATION_PRODUCT: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Prophylaxis for Transrectal Prostate Biopsy
Status: COMPLETED
Conditions: Infection
Interventions: DRUG: Ciprofloxacin|DRUG: trimethoprim-sulfamethoxazole|DRUG: cefuroxime|DRUG: ceftriaxone|DRUG: gentamicin|DRUG: amikacin|DRUG: aztreonam|DRUG: imipenem|DRUG: ceftriaxone|DRUG: gentamicin|DRUG: amikacin|DRUG: aztreonam|DRUG: imipenem
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dairy Lipids, Proteins, and the Metabolic Syndrome - "DairyHealth"
Status: COMPLETED
Conditions: Metabolic Syndrome|Type 2 Diabetes|Cardiovascular Disease|Abdominal Obesity
Interventions: DIETARY_SUPPLEMENT: High content of MC-SFA|DIETARY_SUPPLEMENT: Whey|DIETARY_SUPPLEMENT: Low content of MC-SFA|DIETARY_SUPPLEMENT: Casein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Colorectal Prehabilitation Via Reinfusion or Retention Enema of Ileal Contents Filtrate on the Defecation Functions for the LAR Patients With Ileostomy Before Stoma Closure
Status: RECRUITING
Conditions: Low Anterior Resection Syndrome
Interventions: BEHAVIORAL: preoperative prehabilitation treatment of ileostomy contents filtrate reinfusion through distal ileocolon or retention of enema colon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Toripalimab+ Pemetrexed Plus Carboplatin in Patients With EGFR-mutation Positive and T790M Negative After Progression on EGFR-TKI Treatment
Status: COMPLETED
Conditions: NSCLC
Interventions: COMBINATION_PRODUCT: Drug intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Treatment of Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DEVICE: Study device treatment|DEVICE: Sham device treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Research Study to Show Aprocitentan is Efficacious and Safe to Treat Patients With Uncontrolled Blood Pressure and Chronic Kidney Disease.
Status: WITHDRAWN
Conditions: Hypertension|Renal Insufficiency, Chronic
Interventions: DRUG: Aprocitentan 25 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Hyoscine Bromide in Latent and Active Labor
Status: SUSPENDED
Conditions: Labor, First Stage
Interventions: DRUG: Hyoscine bromide|DRUG: Physiological serum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Phase 1/2 Study of 7MW3711 in Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: 7MW3711 for injection|DRUG: 7MW3711 for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects on Organ Damage and Surgical Outcome of a New Cardiopulmonary Pass System (EVADO)
Status: COMPLETED
Conditions: C.Surgical Procedure; Cardiac
Interventions: DEVICE: EVADO|DEVICE: Conventional CPB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictive Factors to Effectively Terminate Paroxysmal Atrial Fibrillation by Blocking Atrial Selective Ionic Currents
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DRUG: Vernakalant|DRUG: Flecainide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients
Status: COMPLETED
Conditions: Pain|Anesthesia
Interventions: DRUG: Normal Saline|DRUG: Butorphanol|DRUG: Flurbiprofen axetil|DRUG: Remifentanil|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Outcomes of Knee Replacement
Status: TERMINATED
Conditions: Knee Arthroplasty
Interventions: PROCEDURE: Non-MAKO® Robot Assisted Total Knee Arthroplasty|PROCEDURE: MAKO® Robot Assisted Medial Knee Arthroplasty|PROCEDURE: MAKO® Robot Assisted Medial and PF Knee Arthroplasty|DEVICE: RESTORIS Multicompartmental Knee System|DEVICE: Depuy Knee Replacement System|DEVICE: Stryker® Knee Replacement System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Eye Movement Desensitization Reprocessing (EMDR) Study in Bipolar Traumatized Patients
Status: COMPLETED
Conditions: Bipolar Disorder|PTSD
Interventions: OTHER: Eye Movement Desensitization Reprocessing (EMDR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety, Pharmacokinetics, and Antiviral Activity of Lenacapavir Administered Subcutaneously in Human Immunodeficiency Virus (HIV) -1 Infected Adults
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Lenacapavir|DRUG: Placebo|DRUG: B/F/TAF|DRUG: TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunometabolic Pattern of Intermittent Hypoxia During ST-segment Elevation Myocardial Infarction
Status: UNKNOWN
Conditions: Myocardial Ischemic-reperfusion Injury
Interventions: DEVICE: Remote Ischemic Conditioning (RIC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Temozolomide and Radiation Therapy in Treating Patients With Stage IV Malignant Melanoma With Measurable and Unresectable Cancer of the Central Nervous System
Status: TERMINATED
Conditions: Melanoma (Skin)|Metastatic Cancer
Interventions: DRUG: temozolomide|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial Comparing Urea Loaded Nanoparticles to Placebo: a New Concept for Cataract Management
Status: COMPLETED
Conditions: Drug Action Increased
Interventions: DRUG: urea-loaded nanoparticles eye drops|DRUG: Balance Salt Solution eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Dual Task Training on Children With Ataxia After Medulloblastoma Resection
Status: UNKNOWN
Conditions: Ataxia|Medulloblastoma
Interventions: OTHER: Dual Task Training (Motor + Cognitive)|OTHER: Traditional Regular Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Melan-A VLP Vaccine in Early Stage Melanoma Patients
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: BIOLOGICAL: CYT004-MelQbG10
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Electromagnetic Tracking and Optical Imaging With ICG for Hepatic Biopsies
Status: ENROLLING_BY_INVITATION
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: Optical Molecular Imaging|RADIATION: Indocyanine Green
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Prospective Danish National Registry of PTRA in Patients With Renovascular Hypertension
Status: RECRUITING
Conditions: Renal Artery Obstruction|Hypertension, Renovascular|Cardiovascular Diseases|Kidney Diseases
Interventions: DEVICE: Percutaneous transluminal renal angioplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Compare the Efficacy, Pharmacokinetics, Pharmacodynamics, Safety, and Immunogenicity of MAB-22 Versus Prolia®
Status: NOT_YET_RECRUITING
Conditions: Osteoporosis
Interventions: DRUG: MAB-22|DRUG: Prolia®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Maxi-Analgesic Osteoarthritis (OA) Study
Status: WITHDRAWN
Conditions: Osteoarthritis
Interventions: DRUG: Acetaminophen|DRUG: Maxigesic 325|DRUG: Ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NasoShield Study of Safety and Immunogenicity
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: NasoShield|BIOLOGICAL: BioThrax|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Effects of Focused and Unfocused (Radial) ESWT in the Treatment of Patellar Tendinopathy.
Status: COMPLETED
Conditions: Patellar Tendinitis
Interventions: DEVICE: Extracorporeal Shock Wave Therapy (ESWT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Performance of DAILIES TOTAL1 Daily Disposable Contact Lenses in Habitual Soft Lens Wearers Who Report Substantial Digital Device Use
Status: RECRUITING
Conditions: Myopia
Interventions: DEVICE: Delefilcon A contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Effects of Fesoterodine in Men at High Risk for Overactive Bladder/Detrusor Overactivity Post Robotic-Assisted Lap. Prostatectomy
Status: COMPLETED
Conditions: Prostate Adenocarcinoma
Interventions: DRUG: Fesoterodine|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Spectroscopy in Acid Sphingomyelinase Deficiency
Status: RECRUITING
Conditions: Asmd, Visceral Type
Interventions: DIAGNOSTIC_TEST: MR Spectroscopy (MRS)|DIAGNOSTIC_TEST: MR Elastography (MRE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Efficacy of an Acellular Dermal Template for the Treatment of Full Thickness Skin Defects
Status: COMPLETED
Conditions: Full Thickness Skin Defects
Interventions: DEVICE: Novomaix dermal substitute in combination with STSG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Parenteral Protein Concentrations in Critically Ill Patients
Status: COMPLETED
Conditions: Hand Muscle Strain
Interventions: DIETARY_SUPPLEMENT: parenteral protein 1 g/kg|DIETARY_SUPPLEMENT: Parenteral nutrition 2 g/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analysis of HPV and Biomarkers Present in the Biological Fluids of Patients Suffering From Head and Neck Cancer as a Non-invasive Strategy for Detecting Recurrence
Status: RECRUITING
Conditions: Head and Neck Tumors
Interventions: DIAGNOSTIC_TEST: Collection and use of tissue samples, blood and saliva
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MK-3795 (PT2385) for the Treatment of Von Hippel-Lindau Disease-Associated Clear Cell Renal Cell Carcinoma (MK-3795-003)
Status: COMPLETED
Conditions: VHL Gene Mutation|VHL|VHL Syndrome|VHL Gene Inactivation|Von Hippel|Von Hippel-Lindau Disease|Von Hippel's Disease|Von Hippel-Lindau Syndrome, Modifiers of|Clear Cell Renal Cell Carcinoma|Clear Cell RCC|ccRCC
Interventions: DRUG: MK-3795
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Urinary Polymerase Chain Reaction (PCR) and Next Generation Sequencing (NGS) Technology in the Evaluation and Management of Females With Chronic Bladder Pain and Cystitis-like Symptoms
Status: RECRUITING
Conditions: Interstitial Cystitis|Bladder Pain Syndrome
Interventions: DIAGNOSTIC_TEST: Polymerase Chain Reaction and Next-Generation DNA Sequencing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Pentoxifylline on Cerebrovascular Function in Patients With Cerebral Small Vessel Disease(PERFORM)
Status: NOT_YET_RECRUITING
Conditions: Cerebral Small Vessel Diseases
Interventions: DRUG: Pentoxifylline sustained-release tablets|DRUG: Pentoxifylline sustained-release tablets placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tobacco Control Among Business Process Outsourcing (BPO) Employees
Status: UNKNOWN
Conditions: Tobacco Use Cessation
Interventions: OTHER: tobacco cessation intervention|OTHER: Tobacco cessation intervention|OTHER: Tobacco cessation intervention|OTHER: Tobacco cessation intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of BV-AVD in People With Bulky Hodgkin Lymphoma
Status: RECRUITING
Conditions: Hodgkin Lymphoma
Interventions: DRUG: Brentuximab vedotin|DRUG: Doxorubicin|DRUG: Vinblastine|DRUG: Dacarbazine|DRUG: Pembrolizumab|DRUG: Gemcitabine|DRUG: Vinorelbine|DIAGNOSTIC_TEST: FDG-PET/CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Establishing Radiolabelled PSMA as a Target for Glioma Treatment
Status: NOT_YET_RECRUITING
Conditions: Glioma, Malignant
Interventions: DIAGNOSTIC_TEST: PET-MRI|PROCEDURE: Brain tumour biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Development and Feasibility Testing of a Lung Cancer Screening Decision Aid
Status: COMPLETED
Conditions: Lung Neoplasms
Interventions: BEHAVIORAL: LuCaS Decision Aid|BEHAVIORAL: NCI Website
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Platelet Rich Plasma on Ovarian Reserve Parameters and Intra Cytoplasmic Sperm Injection Outcomes in Patients With Diminished Ovarian Reserve
Status: NOT_YET_RECRUITING
Conditions: IVF
Interventions: BIOLOGICAL: Intra ovarian by platelet rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Huzhang Granules for Acute Gouty Arthritis
Status: UNKNOWN
Conditions: Gouty Arthritis
Interventions: DRUG: Huzhang granule|DRUG: Etoricoxib|DRUG: Huzhang granule Placebo|DRUG: Etoricoxib Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NAD Supplementation to Prevent Progressive Neurological Disease in Ataxia Telangiectasia
Status: ACTIVE_NOT_RECRUITING
Conditions: Ataxia Telangiectasia
Interventions: DRUG: Nicotinamide ribonucleoside
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AZD9291 in Combination With Ascending Doses of Novel Therapeutics
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Non Small Cell Lung Cancer
Interventions: DRUG: Part A - AZD9291 in combination with AZD6094|DRUG: Part A - AZD9291 in combination with continuous selumetinib (Asian subjects)|DRUG: Part A - AZD9291 in combination with continuous selumetinib (non-Asian subjects)|DRUG: Part A - AZD9291 in combination with intermittent selumetinib|DRUG: Part A - AZD9291 in combination with MEDI4736|DRUG: Part B - AZD9291 in combination with AZD6094|DRUG: Part B - AZD9291 in combination with selumetinib|DRUG: Part B - AZD9291 in combination with MEDI4736|DRUG: Part C - AZD6094 monotherapy (Japan only)|DRUG: Part C - AZD9291 in combination with AZD6094 (Japan only)|DRUG: Part D - AZD9291 in combination with AZD6094
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compassionate Use of Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Gastrointestinal Tract
Status: COMPLETED
Conditions: Graft Versus Host Disease
Interventions: DRUG: beclomethasone dipropionate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pancreatic Resection, Malnutrition and Readmission
Status: COMPLETED
Conditions: Pancreatic Cancer|Malnutrition
Interventions: DIETARY_SUPPLEMENT: Nestle Impact Advanced Recovery nutritional supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety of a Influenza Vaccine Produced Either in Mammalian Cell Culture or in Embryonated Hen Eggs in Adults and Elderly With and Without Underlying Medical Conditions, and Immunogenicity in a Subset of Subjects With Underlying Medical Conditions
Status: COMPLETED
Conditions: Seasonal Influenza|Vaccine
Interventions: BIOLOGICAL: Cell-derived influenza vaccine|BIOLOGICAL: Egg-derived influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: a Retrospective Study on the Systemic Treatment of LPP and FFA
Status: COMPLETED
Conditions: Cicatricial Alopecia|Lichen Planopilaris|Lichen Plano-Pilaris|Frontal Fibrosing Alopecia|Hair Diseases|Scarring Alopecia|Hair Loss/Baldness
Interventions: DRUG: Hydroxychloroquine|DRUG: Methotrexate|DRUG: Cyclosporine A|DRUG: Retinoids
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SCIB1 and iSCIB1+ in Melanoma Patients Receiving Nivolumab With Ipilimumab or SCIB1 With Pembrolizumab (The SCOPE Study)
Status: RECRUITING
Conditions: Malignant Melanoma|Melanoma (Skin)|Melanoma Stage III|Melanoma Stage IV
Interventions: BIOLOGICAL: SCIB1 or iSCIB1+ DNA vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Left-colon WEC May Reduce Insertion Time Compared With Whole-colon WEC.
Status: COMPLETED
Conditions: Polyp|Pain
Interventions: OTHER: Air colonoscopy|OTHER: Water exchange colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: The Role of Modified Ultrafiltration Following Open Heart Surgery
Status: COMPLETED
Conditions: Heart; Surgery, Heart, Functional Disturbance as Result
Interventions: PROCEDURE: Conventional Ultrafiltration alone on Cardiopulmonary bypass|PROCEDURE: Conventional Ultrafiltration followed by Modified Ultrafitration on Cardiopulmonary bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Plasma Lipoprotein Response to Glucagon-like Peptide-2
Status: COMPLETED
Conditions: Hyperlipidemias
Interventions: DRUG: Teduglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy Study of CF101 to Treat Keratoconjunctivitis Sicca
Status: COMPLETED
Conditions: Keratoconjunctivitis Sicca
Interventions: DRUG: CF101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy Combination: Irradiated PD-L1 CAR-NK Cells Plus Pembrolizumab Plus N-803 for Subjects With Recurrent/Metastatic Gastric or Head and Neck Cancer
Status: RECRUITING
Conditions: Gastroesophageal Junction (GEJ) Cancers|Advanced HNSCC
Interventions: DRUG: N-803|DRUG: Pembrolizumab|BIOLOGICAL: PD-L1 t-haNK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Use of Omega-3 Fatty Acids to Improve Outcomes in Individuals With Sickle Cell Disease
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: DIETARY_SUPPLEMENT: Plant-based omega-3-FA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Aerobic Exercise on Inhibitory Control of Excutive Function in Spastic Hemiplegic C.P
Status: COMPLETED
Conditions: Spastic Hemiplegic Cerebral Palsy
Interventions: OTHER: Aerobic Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Animal-assisted Therapy in Patients With Borderline Personality Disorder and Addictions.
Status: NOT_YET_RECRUITING
Conditions: Diagnosis, Dual (Psychiatry)
Interventions: BEHAVIORAL: Animal-assisted therapy (AAT|BEHAVIORAL: Usual treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endothelial Hyperpolarization in Humans
Status: TERMINATED
Conditions: Hyperlipidemia
Interventions: DRUG: Tetraethylammonium (TEA)|DRUG: L-NG-monomethyl Arginine (L-NMMA)|DRUG: Bradykinin|DRUG: Sodium nitroprusside|DRUG: Acetylcholine|DRUG: Saline|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Locally Produced Cloth Face Mask and COVID-19 Like Illness Prevention
Status: UNKNOWN
Conditions: COVID-19|Respiratory Illness
Interventions: OTHER: Certified cloth face mask plus preventive information|BEHAVIORAL: Preventive information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Hemoccult, Magstream and OC-Sensor Faecal Occult Blood Tests in Colorectal Cancer Screening
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: OTHER: Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Efficacy and Mechanisms of Acupuncture for Patients With Advanced Pancreatic Cancer Pain
Status: UNKNOWN
Conditions: Pancreatic Cancer|Pain
Interventions: DEVICE: Acupuncture|DEVICE: Placebo acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study of Durvalumab +/- Oleclumab as Neoadjuvant Therapy for Muscle-invasive Bladder Cancer (BLASST-2)
Status: COMPLETED
Conditions: Muscle Invasive Bladder Cancer
Interventions: DRUG: Durvalumab|DRUG: Oleclumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Resistance Training Preconditioning on Skeletal Muscle Recovery From a Period of Disuse in Young Adults
Status: NOT_YET_RECRUITING
Conditions: Atrophy, Disuse|Atrophy, Muscular
Interventions: OTHER: Resistance Training Preconditioning|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Repeat Single Oral Dose Study of IPED2015 in Healthy Male Subjects With Erectile Dysfunction
Status: UNKNOWN
Conditions: Erectile Dysfunction
Interventions: DRUG: IPED2015|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Evaluate the Safety and Effectiveness of MK0217 to Prevent and Treat Bone Loss (0217-193)(COMPLETED)
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: MK0217/Duration of Treatment : 12 Months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of a Minimally Invasive Internal Fixation Device for Treatment of Unstable Pelvic Ring Fractures
Status: RECRUITING
Conditions: Unstable Pelvic Fractures
Interventions: PROCEDURE: minimally invasive internal fixation device "infix"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Perianal Fistulas in Crohn's Disease With Autologous Microfragmented Adipose Tissue With the Lipogems System
Status: RECRUITING
Conditions: Crohn Disease|Fistula|Adipose Tissue
Interventions: PROCEDURE: Perianal fistula surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A 12-Week Treatment Study to Evaluate the Effectiveness of Albuterol Multidose Dry Powder Inhaler With Integrated Electronic Module Digital System (eMDPI DS) in Participants13 Years or Older With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Albuterol eMDPI DS|DRUG: albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GOLD 0 - DLCO 1: A Look Beyond the Obstruction. Is Spirometry Enough for COPD (Chronic Obstructive Pulmonary Disease) Screening?
Status: NOT_YET_RECRUITING
Conditions: COPD, Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Standard Care|OTHER: Standard Care plus oxidative stress study plus inflammation biomarkers study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Of OX40 Agonist PF-04518600 Alone And In Combination With 4-1BB Agonist PF-05082566
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: PF-04518600|DRUG: PF-04518600|DRUG: PF-04518600 plus PF-05082566|DRUG: PF-04518600 plus PF-05082566
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Consent and Survey Procedures for Young MSM in Web-based HIV Prevention
Status: COMPLETED
Conditions: Healthy
Interventions: BEHAVIORAL: Video consent (high-tech)|BEHAVIORAL: Video consent (low-tech)|BEHAVIORAL: FAQ format consent|BEHAVIORAL: Standard consent|BEHAVIORAL: PDF informed consent document
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Heparin Anticoagulation in Septic Shock
Status: TERMINATED
Conditions: Septic Shock|Vasodilatory Shock
Interventions: DRUG: Unfractionated heparin|OTHER: Venous thromboprophylaxis (VTE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Safety and Efficacy of ThisCART19A in Adult Patients With B-NHL After Failure of Autologous Chimeric Antigen Receptor T- Cell(CAR-T) Therapy
Status: UNKNOWN
Conditions: Non-Hodgkin's Lymphoma
Interventions: BIOLOGICAL: ThisCART19A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Algovita Spinal Cord Stimulation System Hi-Fi Study
Status: TERMINATED
Conditions: Chronic Pain
Interventions: DEVICE: Ultra-high pulse width stimulation|DEVICE: Traditional pulse width stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Distribution of Topical Nasal Medication Within the Nasal Cavity and Sinuses by Radiographic Comparison
Status: COMPLETED
Conditions: Chronic Sinusitis
Interventions: RADIATION: Sinus CT Scan|DRUG: Omnipaque 240 Contrast Solution|DRUG: Omnipaque 240 mg I/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluating the Safety and Immunogenicity of a Tetravalent Dengue Vaccine (TetraVax-DV) TV005 in Flavivirus-Naive Adults 50 to 70 Years of Age
Status: COMPLETED
Conditions: Dengue
Interventions: BIOLOGICAL: TetraVax-DV TV005|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intranasal Ketamine With Dexmedetomidine for the Treatment of Children With Autism Spectrum Disorder
Status: SUSPENDED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: ketamine and dexmedetomidine|DRUG: ketamine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study in Adults to Assess the Safety and Efficacy of Inhaled IBIO123, for Post-exposure Prophylaxis of COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: IBIO123|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bioenhancing Effects of Black Pepper With Turmeric on Pain Ratings
Status: COMPLETED
Conditions: Pain
Interventions: OTHER: Turmeric|OTHER: Turmeric+Black Pepper
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Premedication to Reduce Amivantamab Associated Infusion Related Reactions
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Dexamethasone|DRUG: Montelukast|DRUG: Methotrexate|DRUG: Amivantamab|DRUG: Lazertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Compare the Efficacy of Celiprolol to Placebo in Patients With Vascular Ehlers-Danlos Syndrome
Status: RECRUITING
Conditions: Vascular Ehlers-Danlos Syndrome
Interventions: DRUG: ACER-002 (celiprolol) 200 mg BID|DRUG: Placebo BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vedolizumab IV 300 mg in the Treatment of Fistulizing Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Vedolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Consumption of a Lactobacillus Strain on the Incidence of Covid-19 in the Elderly
Status: UNKNOWN
Conditions: SARS CoV-2 Infection|Elderly
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Lactobacillus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Preventing Prescription Stimulant Diversion and Medication Misuse Via a Web-Based Simulation Intervention
Status: RECRUITING
Conditions: Prescription Drug Abuse (Not Dependent)|Intentional Misuse
Interventions: OTHER: Web-based placebo presentation|BEHAVIORAL: Web-based simulation active intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Probiotics and Multi-Drug Resistant Urinary Tract Infection
Status: COMPLETED
Conditions: Urinary Tract Infections|Recurrent UTI|Antibiotic Resistant Infection
Interventions: DIETARY_SUPPLEMENT: Bifidobacterium infantis|OTHER: Placebo|DRUG: Antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Support Techniques on Anxiety and Physical Reaction From Dental Treatment
Status: UNKNOWN
Conditions: Dental Anxiety|Dental Diseases|Dental Trauma
Interventions: DEVICE: with deep touch pressure application|DEVICE: without deep touch pressure application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Efficiency of One Day Patient/Caregiver Psychoeducation on the Caregiver's Burden
Status: RECRUITING
Conditions: Bipolar Disorder|Caregiver Burden
Interventions: BEHAVIORAL: Bp OneDay psychoeducation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BTZ-043 Dose Evaluation in Combination and Selection
Status: RECRUITING
Conditions: Tuberculosis, Pulmonary|Other Specified Pulmonary Tuberculosis
Interventions: DRUG: BTZ-043|DRUG: Bedaquiline|DRUG: Delamanid|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Misoprostol and Oxytocin in Uniject® for Postpartum Hemorrhage Prevention in Communities
Status: WITHDRAWN
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Misoprostol|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Safety and Effectiveness Study of Intraspinal Gabapentin (MDT2004) for the Treatment of Chronic Pain
Status: TERMINATED
Conditions: Chronic Intractable Pain
Interventions: DRUG: Intraspinal Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Neuroscience Education and Biomedical Pain Education in Primary Dysmenorrhea
Status: RECRUITING
Conditions: Primary Dysmenorrhea
Interventions: OTHER: Exercise training|OTHER: Pain neuroscience education|OTHER: Biomedical pain education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cilengitide in Treating Patients Who Are Undergoing Surgery for Recurrent or Progressive Glioblastoma Multiforme
Status: TERMINATED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Tumor
Interventions: DRUG: cilengitide|PROCEDURE: therapeutic conventional surgery|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of GnRH Agonist Trigger for Final Follicle Maturation in Women Undergoing Assisted Reproductive Technologies
Status: COMPLETED
Conditions: Sterility|Infertility
Interventions: DRUG: Triptorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Lobaplatin and Paclitaxel in Advanced Gastric Cancer Patients With D2 Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy
Status: RECRUITING
Conditions: Gastric Cancer|Chemotherapy Effect|Surgery|Metastasis|Survival
Interventions: DRUG: Paclitaxel|DRUG: Lobaplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT