pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Everolimus Aging Study
Status: RECRUITING
Conditions: Aging|Insulin Resistance
Interventions: DRUG: Everolimus 0.5 MG once per day|DRUG: Everolimus 5 MG once per week|DRUG: Placebo once per day|DRUG: Placebo once per week
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of JZP-258 in Subjects With Narcolepsy With Cataplexy
Status: COMPLETED
Conditions: Narcolepsy With Cataplexy
Interventions: DRUG: JZP-258|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Gastrointestinal Microbes on Digestion of Resistant Starch and Tryptophan Availability to Humans
Status: UNKNOWN
Conditions: Type II Diabetes
Interventions: DIETARY_SUPPLEMENT: Potato Starch (Bob's Red Mill)|DIETARY_SUPPLEMENT: Pregelatinized Starch (Resource ThickenUp)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability and PK of AZD1152 in Patients With Relapsed Acute Myeloid Leukaemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukaemia
Interventions: DRUG: AZD1152
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Vilazodone in Pediatric Patients With Major Depressive Disorder (VLZ-MD-22)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Vilazodone|DRUG: Placebo|DRUG: Fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rhodospirillum Rubrum and Cholesterol
Status: COMPLETED
Conditions: Cholesterol Metabolism
Interventions: DIETARY_SUPPLEMENT: Rhodospirillum rubrum|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The HEARTFELT Study
Status: NOT_YET_RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: Heartfelt Device installed|OTHER: Standard care|DEVICE: Direct-to-patient alerts|DEVICE: RPMC care|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Prevalence of Acute Hepatic Porphyria in Postural Tachycardia Syndrome
Status: RECRUITING
Conditions: Postural Orthostatic Tachycardia Syndrome|Acute Hepatic Porphyria
Interventions: DIAGNOSTIC_TEST: Autonomic Function Testing|DIAGNOSTIC_TEST: Genetic Testing|DIAGNOSTIC_TEST: Urine Testing|DIAGNOSTIC_TEST: Blood laboratory Testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of the Efficacy of the Artificial Pancreas Combined With a Qualitative Meal Size Estimation to Control Postprandial Glucose Levels
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Single-hormone closed-loop system|DEVICE: Insulin pump|DEVICE: Continuous glucose monitoring system|DRUG: Aspart or Lispro|OTHER: Carbohydrate counting|OTHER: Simplified qualitative meal-size estimation strategy|OTHER: 3-week intervention|OTHER: 1-hour postprandial exercise (sub-study)|OTHER: 2-hour postprandial exercise (sub-study)|OTHER: Exercise announcement and meal bolus reduction (sub-study)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ADI-PEG 20 in Patients With Advanced Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma|Skin Cancer|Neoplasm
Interventions: DRUG: ADI PEG 20
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closed Kinetic Chain Exercises for Balance and Gait Rehabilitation for People With MS
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis
Interventions: COMBINATION_PRODUCT: Telko plus conventional physical therapy (CPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of Hepatitis B Vaccination in Methadone Maintenance Treatment Patients
Status: COMPLETED
Conditions: Hepatitis B Vaccine
Interventions: BIOLOGICAL: 60 µg dose hepatitis B vaccine|BIOLOGICAL: 20 µg dose hepatitis B vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Does Adding an Additional Numbing Medication Injection in the Thigh Help With Pain Control After Knee Replacement Surgery?
Status: COMPLETED
Conditions: Knee Osteoarthritis|Knee Rheumatism
Interventions: DRUG: Obturator nerve regional block|DRUG: Adductor canal regional block|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azacitidine in Patients Undergoing Matched Unrelated Stem Cell Transplantation
Status: TERMINATED
Conditions: Leukemia, Myeloid, Acute|Myelodysplastic Syndromes|Precursor Cell Lymphoblastic Leukemia-Lymphoma
Interventions: DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Platelet Reactivity In Patients Undergoing Elective Stent Placement on Clopidogrel to Guide Alternative Therapy With Prasugrel (TRIGGER-PCI)
Status: TERMINATED
Conditions: Coronary Artery Disease (CAD)
Interventions: DRUG: Prasugrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Usability Study to Assess the Reveal LINQ Insertable Cardiac Monitor System
Status: COMPLETED
Conditions: Syncope|Recurrent Symptomatic Atrial Fibrillation
Interventions: DEVICE: Insertable Cardiac Monitor Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of HFNO Therapy on Respiratory Effort After Extubation
Status: RECRUITING
Conditions: Respiratory Failure|Post Extubation Acute Respiratory Failure Requiring Reintubation
Interventions: OTHER: High Flow Nasal Oxygen|OTHER: Conventional Oxygen Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Minimally Invasive Treatments for Pilonidal Disease: LA POPA Trial (Laser And Pit-picking OR Pit-picking Alone)
Status: NOT_YET_RECRUITING
Conditions: Pilonidal Sinus|Pilonidal Disease|Pilonidal Sinus of Natal Cleft|Pilonidal Disease of Natal Cleft|Pilonidal Sinus Without Abscess
Interventions: PROCEDURE: Pit-picking surgery|PROCEDURE: Pit-picking surgery with Sinus Laser assisted Closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of CP101 for the Prevention of Recurrent CDI (PRISM4)
Status: TERMINATED
Conditions: Recurrent C. Difficile Infection
Interventions: BIOLOGICAL: CP101|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison in Frequency of Hypotension Between Remimazolam and Propofol in Hip Surgery
Status: RECRUITING
Conditions: Remimazolam|Propofol|Orthopedic Procedures|Sedatives|Anesthesia, Spinal
Interventions: DRUG: Remimazolam|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Study of the UltraShape® Contour I-Y for Non-Invasive Reduction in Abdominal Circumference
Status: UNKNOWN
Conditions: Reduction in Abdominal Circumference
Interventions: DEVICE: Treatment with Contour I-Y system|DEVICE: Treatment with Contour I-Y system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety, Pharmacokinetics and Pharmacodynamics of JNJ-64457107 in Participants With Advanced Stage Tumors
Status: COMPLETED
Conditions: Advanced Solid Neoplasms
Interventions: DRUG: JNJ-64457107
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Treatment With Cryotherapy Alone Versus Cryotherapy Plus Salicylic Acid Dressing for Planter Warts
Status: COMPLETED
Conditions: Plantar Wart
Interventions: PROCEDURE: Cryotherapy Alone|COMBINATION_PRODUCT: Cryotherapy plus Salicylic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine on Post-operative Blood Pressure in Bain Arteriovenous Malformation Embolization
Status: UNKNOWN
Conditions: Anesthesia
Interventions: DRUG: Dexmedetomidine|OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Skin Stretch Sensory Stimuli and TENS in Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathy
Interventions: OTHER: Skin stretch sensory stimuli|OTHER: Transcutaneous Electrical nerve stimulation|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Immunogenicity, Reactogenicity and Safety of the Combined Measles, Mumps and Rubella Vaccine Produced by Bio-Manguinhos/Fiocruz in Children 12-15 Months of Age, Followed by Tetraviral Vaccine in Children 15-18 Months.
Status: COMPLETED
Conditions: Measles|Mumps|Rubella|Varicella
Interventions: BIOLOGICAL: MMR Bio-Manguinhos|BIOLOGICAL: MMR GlaxoSmithKline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Accelerated cTBS on Metabolic Dysfunction in People With Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Metabolic Disturbance|Eating Behavior|Transcranial Magnetic Stimulation
Interventions: DEVICE: accelerated theta burst stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GW501516 In Subjects Who Have Low Level Of High-Density Lipoprotein Cholesterol
Status: COMPLETED
Conditions: Dyslipidaemias|Dyslipidaemia
Interventions: DRUG: GW501516 oral tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Preventing Posttraumatic Osteoarthritis With Physical Activity Promotion
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Injuries|Exercise|Cartilage, Articular|Knee Injuries|Osteoarthritis|Osteoarthritis, Knee|Arthritis|Joint Diseases
Interventions: BEHAVIORAL: Physical Activity Promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LDK378 Versus Chemotherapy in Previously Untreated Patients With ALK Rearranged Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Ceritinib|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palliative Treatments for Patients With Advanced Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Hepatectomy|Hepatocellular Carcinoma|Sorafenib
Interventions: PROCEDURE: hepatic resection|PROCEDURE: transcatheter hepatic arterial chemoembolization|DRUG: sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Tolerability of Prophylactic Emicizumab in Hemophilia A Patients With Inhibitors
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: Emicizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decitabine for Poor Graft Function Post Allo-HSCT
Status: NOT_YET_RECRUITING
Conditions: Poor Graft Function
Interventions: DRUG: Decitabine|DRUG: Granulocyte Colony-Stimulating Factor|DRUG: Thrombopoietin Receptor Agonist|DRUG: Recombinant human erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glutamine Supplementation in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Immune Function
Interventions: DIETARY_SUPPLEMENT: Glutamine|DIETARY_SUPPLEMENT: L-alanine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: HMB Supplementation in Addition to Multicomponent Exercise in Old Adults
Status: COMPLETED
Conditions: Aging|Frail Elderly Syndrome|Physical Activity
Interventions: DIETARY_SUPPLEMENT: HMB dietary supplementation|OTHER: Multicomponent physical exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phentermine/Topiramate in Adolescents With Type 2 Diabetes and Obesity
Status: RECRUITING
Conditions: Pediatric Obesity
Interventions: DRUG: Phentermine/Topiramate (Qsymia)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: KTP Green Light Prostatectomy Compared With Open Prostatectomy
Status: COMPLETED
Conditions: BPH (Benign Prostatic Hyperplasia)
Interventions: PROCEDURE: KTP Green Light Prostatectomy|DEVICE: Green Light|PROCEDURE: Open prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of High Tibial Osteotomy in Preventing Degenerative Disease Progression in Medial Knee Osteoarthritis.
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Osteoarthritis|Cartilage Degeneration|Malalignment, Bone
Interventions: PROCEDURE: valgus producing medial opening wedge high tibial osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin for Preventing Disease Metastasis in Patients With Resected High-Risk Stage IIA Melanoma
Status: RECRUITING
Conditions: Clinical Stage IIA Cutaneous Melanoma AJCC v8
Interventions: DRUG: Atorvastatin|DRUG: Placebo Administration|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|OTHER: Electronic Health Record Review
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Lactulose and/or Polyethylene Glycol Solution for Bowel Preparation for Colonscopy Procedures
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: 100 ml lactulose combined with 1 L PEG|DRUG: 100 ml lactulose combined with 2 L PEG|DRUG: 200 ml lactulose|DRUG: 3 L Polyethylene glycol solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety Study of a New Leuprolide Acetate 17 mg Depot to Treat Prostate Cancer Patients
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: leuprolide acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating the Safety and Efficacy of Euiiyin-tang on Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Euiiyin-tang|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stromal Cells for Haplo Hematopoietic Cell Transplantation for Sickle Cell Disease
Status: WITHDRAWN
Conditions: Sickle Cell Disease
Interventions: BIOLOGICAL: Autologous MSCs|BIOLOGICAL: Autologous MSCs|BIOLOGICAL: Autologous MSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intranasal Oxytocin on Appetite and Caloric Intake in Men and Women
Status: COMPLETED
Conditions: Eating Behavior
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Adequate Duration of Antibiotic Treatment in Community-acquired Pneumonia With High Risk Class and Adequate Initial Clinical Response
Status: UNKNOWN
Conditions: Community-acquired Pneumonia
Interventions: DRUG: Moxifloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intradermal Versus Intramuscular Trivalent Influenza Vaccine in Adult Solid Organ Transplant Recipients
Status: COMPLETED
Conditions: Influenza Vaccine
Interventions: BIOLOGICAL: Influenza vaccine: Vaxigrip or Fluviral and Intanza
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Trial Comparing Avg. Global Qual of Lifescore in Hypo Frac. RT vs Conv. Frac. in H&N Cancers
Status: NOT_YET_RECRUITING
Conditions: Radiation Treatment
Interventions: RADIATION: Radiotherapy - hypofractionated|RADIATION: Radiotherapy - Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telemedicine in Atrial Fibrillation: Randomized Clinical Trial in Primary Care (AtrialConnect)
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: Clinical monitoring using the Ti.Care app (https://ti.care/es)|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mindful Breathing and tDCS for Depression
Status: COMPLETED
Conditions: Depression|Depressive Disorder
Interventions: DEVICE: Transcranial Direct Current Stimulation|BEHAVIORAL: Mindful Breathing|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: UCLM802 (Anti-Mesothelin CAR-T) Cell Injection in Patients With Mesothelin-positive Advanced Malignant Solid Tumors
Status: RECRUITING
Conditions: Mesothelin-positive Advanced Malignant Solid Tumors
Interventions: BIOLOGICAL: UCLM802 Cell Injection (Anti-mesothelin CAR-T cells)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Study to Evaluate Safety and Immunogenicity of a Live-attenuated Chikungunya Vaccine in Adolescents
Status: COMPLETED
Conditions: Chikungunya
Interventions: BIOLOGICAL: Active|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Perioperative Use of Gabapentin To Decrease Narcotic Requirements in Spinal Fusion
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Gabapentin|DRUG: Placebo|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrent Training on Patients With Type-II DM Associated PAD.
Status: ENROLLING_BY_INVITATION
Conditions: Type 2 Diabetes With Peripheral Angiopathy
Interventions: OTHER: Concurrent Training|OTHER: Aerobic Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eltrombopag and High-dose Dexamethasone as First Line Treatment for IT
Status: COMPLETED
Conditions: Immune Thrombocytopenic Purpura
Interventions: DRUG: Eltrombopag and dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Nerve Block (Femoral - Sciatic - Obturator) Versus General Anesthesia for Arthroscopic ACL Repair
Status: UNKNOWN
Conditions: Arthroscopic ACL Rerpair|Surgery|Anesthesia Care
Interventions: OTHER: Ultrasound Guided Femoral Sciatic Obturator nerve blocks|OTHER: General Anesthesia femoral bolus|OTHER: General anesthesia femoral continuous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Immunogenicity of Intranasal BPZE1 Vaccination in Healthy Adults
Status: COMPLETED
Conditions: Pertussis|Pertussis Immunisation
Interventions: BIOLOGICAL: BPZE1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Efficacy and Safety of Tiotropium in Children 6 to 11 Years Old With Moderate Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Tiotropium bromide|DRUG: Tiotropium bromide|DRUG: Tiotropium bromide|DRUG: Tiotropium bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginally Administered Versus Per Oral Misoprostol in Induction of Labour
Status: COMPLETED
Conditions: Labour Induction
Interventions: DRUG: Misoprostol, modified-release pessary|DRUG: Misoprostol, per-oral tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a New Anti-HIV Drug (AG1549) Plus Viracept (Nelfinavir) Plus Combivir (Zidovudine/Lamivudine) in HIV-Infected Patients
Status: SUSPENDED
Conditions: HIV Infections
Interventions: DRUG: Lamivudine/Zidovudine|DRUG: Capravirine|DRUG: Nelfinavir mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Abdominal Hypopressive Technique on Postpartum Low Back Pain
Status: COMPLETED
Conditions: Postpartum
Interventions: OTHER: Abdominal hypopressive Exercises (AHE)|OTHER: General exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Colorectal Cancer Screening With Improved Shared Decision Making
Status: COMPLETED
Conditions: Colorectal Cancer Screening|Shared Decision Making
Interventions: BEHAVIORAL: Shared Decision Making for Colorectal Cancer Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Different Materials Contribution to Implants Stability
Status: COMPLETED
Conditions: Dental Implant Failure Nos
Interventions: OTHER: platelet-rich fibrin placement|OTHER: xenogenic graft placement|OTHER: no extra material|PROCEDURE: tooth extraction|PROCEDURE: immediate implant placement|OTHER: collagen membran placement|PROCEDURE: raising flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Autologous Fat Injection Into the Intersphincter Space in Fecal Incontinence: a Randomized, Placebo-controlled, Cross-over, Double-blind Trial
Status: RECRUITING
Conditions: Fecal Incontinence
Interventions: OTHER: injection of autologous fat at Day 0 and injection of saline at 6 months|OTHER: injection of saline at Day 0 and injection of autologous fat at 6 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Condrosulf in the Treatment of Symptomatic OA of the Hand
Status: COMPLETED
Conditions: Osteoarthrosis
Interventions: DRUG: Chondroitin 4&6 sulfate (Condrosulf)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Peer Genetic Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Subject|Prostate Carcinoma
Interventions: BEHAVIORAL: Cancer Educational Materials|OTHER: Questionnaire Administration|OTHER: Educational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Pilot Study on the Feasibility Study of a Novel Virtual Reality (VR)-Based Post-stroke Hemineglect Evaluation System
Status: UNKNOWN
Conditions: Stroke, Complication
Interventions: DEVICE: VR-based post-stroke hemineglect evaluation system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Bioequivalence Study of Torrent Pharmaceuticals Ltd's Bioequivalence Study of Torrent Pharmaceuticals Ltd's Quetiapine Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Torrent's Quetiapine Fumarate Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Clinical Trial to Evaluate Pharmacokinetics, Pharmacodynamics and Safety of Leucostim® Compared to Neupogen®
Status: COMPLETED
Conditions: Leucocytosis
Interventions: BIOLOGICAL: Leucostim®|BIOLOGICAL: Neupogen®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Transcranial Direct Current Stimulation (tDCS) in Human Subjects With PTSD Receiving an Exposure-based, Behavioral Therapy
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: DEVICE: Soterix 1x1 tDCS mini CT|OTHER: Sham Soterix 1x1 tDCS Mini CT|BEHAVIORAL: Written Exposure Therapy (WET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assess Aesthetic Improvement and Onset of QM1114-DP in Subjects With Moderate to Severe Glabellar Lines
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: BIOLOGICAL: QM1114-DP|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Efficacy, Safety and Tolerability of Pramipexole in Patients With Idiopathic Moderate to Severe Restless Legs Syndrome (RLS)
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: Pramipexole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing the Number of Systematic COres During a MRI Target Biopsy
Status: RECRUITING
Conditions: Suspicion of Prostate Cancer With a Positive Multiparametric Magnetic Resonance of the Prostate
Interventions: DIAGNOSTIC_TEST: Prostate biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: LUMINOS-103: A Basket Trial Evaluating the Safety and Efficacy of Lerapolturev (PVSRIPO) and Lerapolturev in Combination With Anti-PD-1/L1 Checkpoint Inhibitors in Patients With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor|Bladder Cancer|Non-muscle-invasive Bladder Cancer
Interventions: BIOLOGICAL: Lerapolturev|OTHER: 5% DDM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene Therapy for the Treatment of Fanconi's Anemia Type C
Status: COMPLETED
Conditions: Fanconi's Anemia|Pancytopenia
Interventions: DRUG: Transduced CD34+ Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Safety and Efficacy of IN-C006 Inj. Compared With RCN301
Status: COMPLETED
Conditions: Parenteral Nutrition
Interventions: DRUG: IN-C006 inj.|DRUG: RCN301
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing the Pharmacokinetic Profile of LY01612 and CAELYX® in Chinese Subjects With Advanced Breast Cancer
Status: COMPLETED
Conditions: Advanced Breast Cancer
Interventions: DRUG: Doxorubicin hydrochloride liposome injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Soy Peptide, Conjugated Linoleic Acid, Overweight or Obese, Body Composition
Status: UNKNOWN
Conditions: Overweight or Obesity
Interventions: DIETARY_SUPPLEMENT: Experimental group|DIETARY_SUPPLEMENT: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Pharmacokinetics and Safety Between Single Administration of "BR6002" and Coadministration of "BR6002A" and "BR6002B" Under Fed Conditions in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Gastric or Duodenal Ulcer
Interventions: DRUG: BR6002A|DRUG: BR6002B|DRUG: BR6002
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study Assessing an Insulin Pump-controlling Algorithm to Minimize Hypo and Hyper in Type 1 During CRC Setting
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: Hypo-Hyper Minimizer (HHM) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Luteinizing Hormone (LH) Supplementation in Gonadotropin-releasing Hormone (GnRH) Antagonist Cycles
Status: COMPLETED
Conditions: Ovarian Stimulation
Interventions: DRUG: rFSH: Follicle Stimulating Hormone|DRUG: rFSH: Follicle Stimulating Hormone|DRUG: rFSH: Follicle Stimulating Hormone and rLH: Luteinizing Hormone (Recombinant Luteotrophin alfa)|DRUG: rFSH: Follicle Stimulating Hormone and rLH: Luteinizing Hormone (Recombinant Luteotrophin alfa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telemedicine Control Tower for the Operating Room: Navigating Information, Care and Safety
Status: COMPLETED
Conditions: Surgery|Surgery--Complications|Perioperative/Postoperative Complications
Interventions: DEVICE: Anesthesia Control Tower monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pharmacologic Treatment Augmentation in Chronic Depression
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Ketamine|DRUG: Placebo|BEHAVIORAL: CBASP|BEHAVIORAL: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on Pharmacokinetics (PK), Efficacy and Safety of Subcutaneous (SC) Versus Intravenous (IV) Rituximab, in Combination With CHOP (Cyclophosphamide, Doxorubicin, Vincristine, Prednisone) in Previously Untreated Participants With CD20 Positive Diffuse Large B-Cell Lymphoma (DLBCL)
Status: COMPLETED
Conditions: Lymphoma, Large B-Cell, Diffuse
Interventions: DRUG: Rituximab IV|DRUG: Rituximab SC|DRUG: Rituximab IV|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|DRUG: Paracetamol|DRUG: Diphenhydramine hydrochloride or alternative antihistamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Ropivacaine Combined With Hydromorphone for CSEA After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Postoperative Analgesia
Interventions: DRUG: Hydromorphone was injected into the subarachnoid space
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of Sipuleucel-T W/ or W/O Radium-223 in Men With Asymptomatic or Minimally Symptomatic Bone-MCRPC
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Radium-223|BIOLOGICAL: Sipuleucel-T
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Safety Study of Two Experimental HIV Vaccines
Status: COMPLETED
Conditions: AIDS Vaccines|HIV Infections|HIV-1
Interventions: DRUG: VRC-HIVADV027-00-VP|DRUG: VRC-HIVADV038-00-VP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: DUAC® Early Onset Efficacy Study in Japanese Subjects
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Duac® fixed dose combination gel|DRUG: ADA 0.1% gel|DRUG: CLDM 1% gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Association Between the Occurrence of a Clinical RElapse and Gut MIcrobiota Modifications: a Cohort Study of Patients With pSOriasis
Status: NOT_YET_RECRUITING
Conditions: Psoriasis|Microbial Colonization
Interventions: OTHER: Fecal sampling|OTHER: Blood sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acceptability of Identifying and Managing Psychological Distress in Inflammatory Bowel Disease: the COMPASS-IBD Study
Status: UNKNOWN
Conditions: IBD|Psychological Distress|Treatment of Illness-related Distress in IBD
Interventions: BEHAVIORAL: COMPASS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Chimeric Monoclonal Antibodies to Shiga Toxins 1 and 2
Status: COMPLETED
Conditions: Shiga Toxin Producing Bacterial Infection
Interventions: DRUG: cαStx1/cαStx2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Prophylactic Heated Humidification on Obstructive Sleep Apnea (OSA) Patient Short Term Compliance to CPAP Therapy
Status: WITHDRAWN
Conditions: Osa Syndrome
Interventions: DEVICE: heated humidification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of VEGF-Antisense Oligonucleotide in Combination With Pemetrexed and Cisplatin for the Treatment of Advanced Malignant Mesothelioma
Status: WITHDRAWN
Conditions: Mesothelioma
Interventions: DRUG: VEGF-Antisense Oligonucleotide , Pemetrexed, Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MTZ Plus AMX in the Treatment of Smokers and Non-smokers
Status: COMPLETED
Conditions: Chronic Periodontitis|Smoking
Interventions: DRUG: Metronidazole plus Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Study of Camrelizumab Combined With Chemotherapy or Anlotinib in Advanced Esophageal Squamous Cell Cancer
Status: NOT_YET_RECRUITING
Conditions: Stage IV Esophagus Squamous Cell Carcinoma
Interventions: DRUG: Camrelizumab|DRUG: Irinotecan|DRUG: Paclitaxel|DRUG: Paclitaxel-albumin|DRUG: Docetaxel|DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Spironolactone on Cardio- and Cerebrovascular Morbidity and Mortality in Hemodialysis Patients
Status: COMPLETED
Conditions: End-stage Renal Failure
Interventions: DRUG: Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Long-term Safety and Efficacy of Efavaleukin Alfa in Participants With Moderately to Severely Active Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Efavaleukin alfa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Identifying Factors That Predict Antidepressant Treatment Response
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Escitalopram|DRUG: Duloxetine|BEHAVIORAL: Cognitive behavioral therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Linagliptin (BI 1356) as Monotherapy or in Combination in Type 2 DM
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: linagliptine 5 mg|DRUG: linagliptine 5 mg and pioglitazone 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SHR-3032 in Healthy Subjects
Status: RECRUITING
Conditions: Prevention of Graft Rejection After Organ Transplantation
Interventions: DRUG: SHR-3032|DRUG: SHR-3032 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Temporary Transvenous Pacemaker Placement by Intracavitary Electrocardiogram Monitoring
Status: UNKNOWN
Conditions: Bradycardia; Syncope|Bradyarrhythmia|Brady-tachy Syndrome|Tachycardia Bradycardia|AVB - Atrioventricular Block|Tachyarrhythmia
Interventions: PROCEDURE: Temporary transvenous cardiac pacing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison Between the Effect of Oxytocin Only and Oxytocin Plus Propranolol on Induction of Labor in Term Pregnancy
Status: UNKNOWN
Conditions: Induction of Labor Affected Fetus / Newborn
Interventions: DRUG: Propranolol|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AI-Guided (GenAIS TM) Versus Standard Physician-Guided Dietary Supplementation for Managing Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: OTHER: Standard therapy group|OTHER: AI-Guided Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Dydrogesterone vs. Vaginal Micronized Progesterone for Luteal Phase Support in Frozen-thawed Embryo Transfer
Status: UNKNOWN
Conditions: ART
Interventions: DRUG: Dydrogesterone 10 MG|DRUG: Endometrin 100Mg Vaginal Insert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Early Gabapentin as an Intervention for Neurorecovery
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Specificity of Neural Correlates for Emotion Processing Deficits in Conduct Disorder and Autism Spectrum Disorders
Status: UNKNOWN
Conditions: Autism-Spectrum Disorder|Conduct Disorder
Interventions: OTHER: neuroimaging session (with simultaneously acquired eye-tracking)|OTHER: Questionnaire (for children) assessing traumatic experiences (Childhood trauma questionnaire (CTQ))|OTHER: Social and Health Assessment (SAHA) questionnaire (for children)|OTHER: Massachusetts Youth Screening Instrument (MAYSI-2) (for children)|OTHER: Interpersonal Reactivity Index (IRI) (for children)|OTHER: Youth Psychopathic Traits Inventory (YPI) (for children)|OTHER: Reactive Proactive Questionnaire (RPQ) (for children)|OTHER: Emotion Regulation Questionnaire (for children)|OTHER: Basic Empathy Scale (BES) (for children)|OTHER: Pubertal Development Scale (PDS) (for children)|OTHER: Alabama Parenting Questionnaire (APQ) (for parents)|OTHER: Inventory of Callous Unemotional Traits (ICU) (for parents)|OTHER: Child Behavior Checklist (CBCL) (for parents)|OTHER: Griffith Empathy Measure (GEM) (for parents)|OTHER: Social Responsiveness Scale (SRS) (for parents)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Proximod Pharmacokinetics in Healthy Subjects and Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Proximod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Surgical Rectus Sheath Block and Intrathecal Morphine
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Bupivacaine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Liposomal Bupivacaine
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Bupivacaine Injection [Marcaine]|DRUG: Bupivacaine Liposome 13.3 MG/ML [Exparel]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of FB704A in Adult With Severe Asthma
Status: RECRUITING
Conditions: Severe Asthma
Interventions: BIOLOGICAL: FB704A placebo|BIOLOGICAL: FB704A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of Stereotactic Body Radiation Therapy for Thymoma Inoma: Therapeutic Effect and Toxicity Assessment
Status: COMPLETED
Conditions: Thymoma|Thymic Tumor
Interventions: RADIATION: stereotactic body radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Efficacy of Intravenous Injection of the Imaging Agent 111In-IPN01087 in Patients With Locally Advanced or Metastatic Pancreatic or Colorectal Cancer.
Status: WITHDRAWN
Conditions: Pancreatic Ductal Adenocarcinoma|Colorectal Cancer
Interventions: DRUG: 111In-IPN01087 Low dose|DRUG: 111In-IPN01087 High dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tear Production by Nasal Neurostimulation Compared to Active Control
Status: COMPLETED
Conditions: Dry Eye|Dry Eye Syndromes|Keratoconjunctivitis Sicca
Interventions: DEVICE: Intranasal Neurostimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pilot Study on Ambulatory Intraocular Pressure and Blood Pressure Monitoring in Glaucoma
Status: COMPLETED
Conditions: Normal-Tension Glaucoma
Interventions: DEVICE: Sensimed Triggerfish|DEVICE: Blood Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Vasopressin Following the Fontan Operation
Status: WITHDRAWN
Conditions: Pleural Effusion|Single-ventricle
Interventions: DRUG: Vasopressin|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Topical Application of Hyaluronic Acid on Stability of Immediate Loading Dental Implant in Posterior Maxilla
Status: COMPLETED
Conditions: Missing Teeth
Interventions: OTHER: Hyaluronic acid|OTHER: conventional implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER