pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of MM-121 in Combination With Paclitaxel in Patients With Advanced Gynecologic and Breast Cancers
Status: COMPLETED
Conditions: Locally Advanced/Metastatic or Recurrent Ovarian Cancer, Fallopian Tube Cancer,|Primary Peritoneal Cancer or Endometrial Cancer|Locally Advanced/Metastatic Her2 Non Overexpressing Breast Cancer
Interventions: DRUG: MM-121|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Punch Biopsy for Diagnosis of Septic and Aseptic Prosthetic Joint Failure
Status: UNKNOWN
Conditions: Wear of Articular Bearing Surface of Internal Prosthetic Joint|Infection Prosthetic|Infections Joint Prosthetic|Prosthetic Joint Infection|Prosthetic Pain
Interventions: DIAGNOSTIC_TEST: Punch biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Epoetin Beta in Treating Fatigue and Anemia in Patients Receiving Palliative Care for Malignant Solid Tumors
Status: COMPLETED
Conditions: Anemia|Fatigue|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: epoetin beta|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Competitive Exergame on Weight Loss, Mental Health, and Social-emotional
Status: NOT_YET_RECRUITING
Conditions: Weight Loss|Mental Health Issue|Overweight and Obesity
Interventions: OTHER: Peer involvement in Two player mode(peer involvement) in Competitive Exergame play|OTHER: Single player mode in Competitive Exergame play|OTHER: Children did not engage in any Competitive Exergame play
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study in Schizophrenic In-patients Treated With Quetiapine Prolong or Oral Risperidone at Flexible Dose
Status: TERMINATED
Conditions: Schizophrenic Disorders
Interventions: DRUG: Quetiapine|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Intranasal Lidocaine in Acute Management of Pediatric Migraine
Status: COMPLETED
Conditions: Migraine in Children|Posttraumatic Headache
Interventions: DRUG: Lidocaine 2% Injectable Solution|DRUG: Normal Saline Flush, 0.9% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A PPG Sensor-Based Feedback Intervention for Heavy Drinking Young Adults
Status: COMPLETED
Conditions: Heavy Drinking|Harmful; Use, Alcohol
Interventions: BEHAVIORAL: Behavioral Self-Management and Feedback|BEHAVIORAL: Behavioral Self-Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improving Sleep to Prevent Depression & Anxiety in Adolescents at High Risk
Status: NOT_YET_RECRUITING
Conditions: Insomnia|Sleep Disturbance|Depressive Symptoms|Anxiety Symptoms
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia|OTHER: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Late-Onset Treatment Study Extension Protocol
Status: COMPLETED
Conditions: Pompe Disease (Late-Onset)|Glycogen Storage Disease Type II (GSD-II)|Glycogenesis Type II|Acid Maltase Deficiency (AMD)
Interventions: BIOLOGICAL: alglucosidase alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preimplantation Genetic Screening in Women of Advanced Maternal Age
Status: COMPLETED
Conditions: Chromosomal Abnormalities
Interventions: PROCEDURE: Preimplantation Genetic Screening|PROCEDURE: IVF without PGS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: The Effects of Different Loading Doses of Dexmedetomidine on The Bispectral Index-Guided Propofol Sedation in Patients Undergoing Advanced Upper Gastrointestinal Endoscopic Procedures: A Randomized Control Study
Status: RECRUITING
Conditions: GIT Endoscopy|Procedural Sedation
Interventions: DRUG: Precedex (Dexmedetomidine) 200 MCG in 2 ML Injection|OTHER: C group: Patients received saline infusion over 10 minutes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Assessing the Patient Experience in Cancer Care
Status: COMPLETED
Conditions: Brain Neoplasm|Breast Neoplasm|Endocrine Gland Neoplasm|Gastrointestinal Neoplasm|Genitourinary Neoplasm|Gynecological Neoplasm|Head and Neck Neoplasm|Lung Neoplasm|Melanoma|Sarcoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Patient Comfort With the Nasal and Oral Insertion of the Endobronchial Ultrasound Bronchoscope
Status: COMPLETED
Conditions: Satisfaction
Interventions: PROCEDURE: Oral EBUS insertion|PROCEDURE: Nasal EBUS insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Acute Effect of Mango Intake (Mangifera Indica L.) on Blood Pressure and Blood Glucose
Status: COMPLETED
Conditions: Blood Pressure
Interventions: OTHER: further fasting|OTHER: white bread consumption|OTHER: mango consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of OMNI Surgical System and iStent for Eyes With OAG (Trident)
Status: TERMINATED
Conditions: Glaucoma, Open-Angle
Interventions: DEVICE: OMNI® Surgical System|DEVICE: iStent inject|DEVICE: OMNI® Surgical System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Losmapimod on Cardiac Conduction as Compared to Placebo and Moxifloxacin
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Losmapimod|DRUG: Moxifloxacin|DRUG: Losmapimod matched Placebo|DRUG: Moxifloxacin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Telephone Assessment and Skill-Building Intervention for Stroke Caregivers
Status: COMPLETED
Conditions: Stroke|Family Caregivers
Interventions: BEHAVIORAL: Telephone Assessment and Skill-Building Kit (TASK II)|BEHAVIORAL: Information, Support, and Referral (ISR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Modified Dose of Rabbit Anti-thymocyte Globulin (rATG) in Children and Adults Receiving Treatment to Help Prepare Their Bodies for a Bone Marrow Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia (AML)|Acute Lymphoid Leukemia (ALL)|Myelodysplastic Syndromes (MDS)
Interventions: OTHER: Personalized rATG (P-rATG)|RADIATION: Hyper fractionated total body irradiation|DRUG: Thiotepa|DRUG: Cyclophosphamide|DRUG: GCSF|DRUG: Busulfan|DRUG: Melphalan|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RPL554 in Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: RPL554|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain Assessment After Canal Preparation by Different NiTi File Systems
Status: COMPLETED
Conditions: Post Operative Pain|Inflammation
Interventions: PROCEDURE: Chemomechanical preparation for root canals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Sevoflurane in Subanesthetic Concentrations on the Forearm Perfusion
Status: UNKNOWN
Conditions: Ischemia/Reperfusion Injury
Interventions: DRUG: Sevoflurane (Preconditioning)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomolecular Analysis for Predicting Response to Regorafenib
Status: RECRUITING
Conditions: Glioblastoma|Glioblastoma, IDH-wildtype
Interventions: DIAGNOSTIC_TEST: Biomolecular tumor analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Oral Sedation in Vitreoretinal Surgery
Status: UNKNOWN
Conditions: Macular Holes|Intraocular Lens Opacification|Vitrectomy|Vitreous Hemorrhage|Retinal Detachment|Epiretinal Membrane|Vitreous Detachment|Intraocular Lens Dislocation
Interventions: DRUG: Oral Sedatives with or Without Analgesia|DRUG: Intravenous Sedatives with or Without Analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Specificity and Sensitivity of 5-ALA Fluorescence in Malignant Brain Tumors
Status: WITHDRAWN
Conditions: Brain Neoplasms
Interventions: DRUG: 5-aminolevulinic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation as a Novel Treatment for Refractory Opioid Use Disorder
Status: RECRUITING
Conditions: Opioid-Related Disorders
Interventions: DEVICE: Deep Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Cryoballoon Ablation of Atrial Fibrillation as First-line Therapy
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: Cryoballoon ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ciltacabtagene Autoleucel and Talquetamab for the Treatment of Participants With High-Risk Multiple Myeloma
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Cilta-cel|DRUG: Talquetamab|DRUG: Daratumumab|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Investigate the Safety, Tolerability and Pharmacokinetics of AZD2516 After Multiple Dosing in Healthy Volunteers
Status: COMPLETED
Conditions: Part A Healthy Young Males and Non-fertile Female Volunteers Aged 20 to 45 Years.|Part B Healthy Young Males and Non-fertile Female Volunteers Aged 20 to 45 and Elderly Volunteers Aged 60 to 80
Interventions: DRUG: AZD2516|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Lu AF35700 in Patients With Treatment-resistant Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Risperidone|DRUG: Olanzapine|DRUG: Lu AF35700|DRUG: Lu AF35700
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Eslicarbazepine Acetate on the Pharmacokinetics of Metformin in Healthy Volunteers
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: Metformin|DRUG: Eslicarbazepine acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of RHH646 for Knee Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: DRUG: RHH646|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Package of Interventions for Environmental Enteropathy
Status: COMPLETED
Conditions: Environmental Enteropathy
Interventions: DRUG: Albendazole|DIETARY_SUPPLEMENT: Zinc|DIETARY_SUPPLEMENT: Multiple Micronutrient Supplement|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Prostacyclin Infusion on Cerebral Vessels and Metabolism in Patients With Subarachnoid Haemorrhage
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage
Interventions: DRUG: Prostacyclin 1 ng/kg/min|DRUG: Prostacyclin 2 ng/kg/min|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Myelodysplastic Syndromes|Mixed Phenotype Acute Leukemia|Myelofibrosis|Chronic Myeloid Leukemia
Interventions: BIOLOGICAL: OrcaGraft (Orca-Q)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Pharmacokinetics (PK) of Corplex™ Donepezil Transdermal Delivery System (TDS) Applied to Different Body Locations
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Donepezil TDS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: European Rare Blood Disorders Platform (ENROL)
Status: RECRUITING
Conditions: Anemia|Bone Marrow Failure|Bleeding Disorder|Iron Metabolism Disorders|Myeloma|Lymphoid Neoplasm|Myeloma, Malignant|Leukemia|Anemia, Sickle Cell|Thalassemia|Blood Cancer|Red Cell Membrane and Enzyme Abnormalities
Interventions: OTHER: Collection of clinical and laboratory data from EHR.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intraoperative Chemotherapy Against Hepatocellular Carcinoma Recurrence
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: sustained released 5-FU and sustained released cisplatin|DRUG: sustained released 5-FU|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Tape Harvesting Study
Status: COMPLETED
Conditions: Atopic Dermatitis|Healthy|Discoid Lupus Erythematosus|Subacute Cutaneous Lupus Erythematosus
Interventions: PROCEDURE: Skin Taping|PROCEDURE: Blood Sampling|PROCEDURE: Skin Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety/Efficacy Study of Intra-coronary Tenecteplase During Balloon Angioplasty to Treat Heart Attacks
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Tenecteplase|DRUG: Sterile Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3D U/S Maternal Fetal Bonding in African American Women
Status: RECRUITING
Conditions: Maternal-Fetal Relations|Maternal Behavior
Interventions: BEHAVIORAL: 3D printed model|BEHAVIORAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TACE Plus Multikinase Inhibitor and I-125 Seeds Brachytherapy for HCC With Branch PVTT
Status: RECRUITING
Conditions: Hepatocellular Carcinoma Non-resectable
Interventions: PROCEDURE: TACE combined with lenvatinib and iodion-125 seeds brachytherapy|PROCEDURE: TACE combined with lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnosis of Sport-related Concussion Using Urine Metabolites
Status: COMPLETED
Conditions: Concussion, Mild|Diagnoses, Syndromes, and Conditions
Interventions: OTHER: urine metabolomics
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Trial for GNX80 in Intermittent Claudication
Status: RECRUITING
Conditions: Intermittent Claudication
Interventions: DRUG: GNX80|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study B2C112060: A Study of the Efficacy and Safety of Vilanterol Inhalation Powder in Adults and Adolescents With Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Vilanterol|DRUG: Salmeterol Inhalation Powder|DRUG: Placebo Inhalation Powder NDPI|DRUG: Placebo Inhalation Powder Diskus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Validity and Safety of IOP Injection MRI Contrast Agent in Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Magnetic Resonance Imaging
Interventions: DRUG: IOP Injection (MPB-1523)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vielight Neuro RX Gamma - Feasibility Pilot
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DEVICE: Neuro RX Gamma synchronous|DEVICE: Sham|DEVICE: Neuro RX Gamma asynchronous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Small Chain Fatty Acid Metabolism in Parkinson Disease: Ketones
Status: TERMINATED
Conditions: Parkinson Disease|Lewy Body Dementia|Parkinson Disease Dementia
Interventions: DIETARY_SUPPLEMENT: Ketone Ester (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Artesunate-amodiaquine and Artemether-lumefantrine for the Treatment of Malaria in Cameroon
Status: UNKNOWN
Conditions: Falciparum Malaria
Interventions: DRUG: Artesunate-amodiaquine drug combination|DRUG: Artemether-lumefantrine drug combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Fasting as a Means to Lose Fluid Overload and Weight in Complicated Obesity
Status: UNKNOWN
Conditions: Intermittent Fasting|Obesity, Morbid|Comorbidities and Coexisting Conditions|Weight Loss|Fluid Retention
Interventions: BEHAVIORAL: Intermittent fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Work Ability of Young Adults With Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: BEHAVIORAL: Personal Resource Building and Inclusive Volunteering Intervention (PVI)|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Naltrexone/Bupropion (Mysimba) to Optimize Weight Outcomes After Obesity Surgery
Status: WITHDRAWN
Conditions: Obesity
Interventions: DRUG: Naltrexone/bupropion|OTHER: Lifestyle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Berodual® Respimat® Versus Berodual® Metered Aerosol (MA) Inhaler in Patients With Asthma, Chronic Obstructive Pulmonary Disease, or Mixed Condition
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Asthma
Interventions: DRUG: Berodual® Respimat®|DRUG: Berodual® MA HFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Anticoagulants and Antithrombotics in Patients With CSDH
Status: RECRUITING
Conditions: Chronic Subdural Hematoma|Anticoagulant-induced Bleeding|Thromboembolic Stroke|Cardiovascular Stroke
Interventions: PROCEDURE: CSDH evacuation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact of Metformin on the Outcome of Gouty Arthritis in a Cohort of Egyptian Gouty Patients.
Status: COMPLETED
Conditions: Gouty Arthritis
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PF-06291874 Multiple Ascending Dose Study In Type 2 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: PF-06291874|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Deferred Embryo Transfer in an In Vitro Program With Single Embryo Transfer Policy
Status: COMPLETED
Conditions: Single Embryo Transfer|Embryo Implantation, Delayed|Pregnancy Rate
Interventions: OTHER: freeze all strategy embryo transfer|OTHER: fresh embryo transfer strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Blood Flow Restriction Training Combined With Abdominal draw-in Maneuver on Transverse Abdominis Strengthening
Status: COMPLETED
Conditions: Blood Flow Restriction|draw-in Maneuver|Transverse Abdominis
Interventions: BEHAVIORAL: blood flow restriction|BEHAVIORAL: sham blood flow restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Post Operative Dressing After Clean Elective Hand Surgery
Status: COMPLETED
Conditions: Trigger Finger Disorder|Carpal Tunnel Syndrome|Ganglion
Interventions: OTHER: Dressing protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Protein Source on Plasma Amino Acid Concentrations In Older Adults
Status: COMPLETED
Conditions: Protein Deposition
Interventions: OTHER: Pork|OTHER: Egg|OTHER: Black beans|OTHER: Almonds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Trial to Investigate the Pharmacokinetics and Safety/Tolerability of CKD-386 in Healthy Adult Volunteers
Status: UNKNOWN
Conditions: Type2 Diabetes Mellitus
Interventions: DRUG: CKD-386 Formulation 1|DRUG: CKD-386 Formulation 2|DRUG: D012, D326 and D337
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Incidence of Sacral and Heel Pressure Ulcers During Acute Care After SCI
Status: UNKNOWN
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Five-layer foam dressing|DEVICE: Heelmedix boot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dose and Duration of Metronidazole and Amoxicillin for Treatment of Chronic Periodontitis
Status: UNKNOWN
Conditions: Chronic Periodontitis
Interventions: PROCEDURE: Scaling and root planing (SRP)|DRUG: Metronidazole 250 (7 days)|DRUG: Metronidazole 400 (7 days)|DRUG: Metronidazole 250 (14 days)|DRUG: Metronidazole 400 (14 days)|DRUG: Amoxicillin|OTHER: Placebo 250 (7 days)|OTHER: Placebo 400 (7 days)|OTHER: Placebo 400 (14 days)|OTHER: Placebo 500
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib Plus DEB-TACE and HAIC vs. Lenvatinib Plus DEB-TACE for Large HCC With PVTT
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma Non-resectable
Interventions: COMBINATION_PRODUCT: Len+DEB-TACE+HAIC|COMBINATION_PRODUCT: Len+DEB-TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TACE Plus Axitinib and Hydroxychlorquine for Liver-Dominant Metastatic Colorectal Cancer (CRC)
Status: TERMINATED
Conditions: Colorectal Neoplasms Malignant
Interventions: DRUG: Axitinib 5 MG|DRUG: Hydroxychloroquine Pill|PROCEDURE: trans arterial chemoembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability and Pharmacokinetics of Oral Brexpiprazole (OPC- 34712) in Adolescents With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Brexpiprazole (OPC-34712)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of the Research for Mutation of K-ras and EGFR in CTCs From Metastatic Non Small Cells Bronchial Carcinomas
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer Metastatic
Interventions: BIOLOGICAL: CTC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Investigation of a Medical Device for the Immobilisation of Radius and Ulna Fractures in Paediatric Patients
Status: RECRUITING
Conditions: Fractures, Bone
Interventions: DEVICE: T3DDY01|DEVICE: PLASTER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Physical Activity Monitored by Fitbit Charge 2 in Improving Quality of Life in Participants With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Endometrioid Tumor|Fallopian Tube Mucinous Neoplasm|Fallopian Tube Serous Neoplasm|Ovarian Clear Cell Tumor|Ovarian Endometrioid Tumor|Ovarian Mucinous Tumor|Ovarian Serous Tumor|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DEVICE: Monitoring Device|OTHER: Physical Activity|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I Trial of AZD3965 in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Adult Solid Tumor|Diffuse Large B Cell Lymphoma|Burkitt Lymphoma
Interventions: DRUG: AZD3965|DRUG: AZD3965|DRUG: AZD3965|DRUG: AZD3965|DRUG: AZD3965|DRUG: AZD3965|DRUG: AZD3965
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Demonstrate the Value of Using Hypnosis in Chimiotherapy- Induced Chronic Neuropathies
Status: UNKNOWN
Conditions: Chemotherapy-induced Neuropathy
Interventions: BEHAVIORAL: Nurse interview|BEHAVIORAL: Hypnosis sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Static Stretching Duration on Gastrocnemius Muscle Vascularization
Status: COMPLETED
Conditions: Muscle Stretching Exercises
Interventions: BEHAVIORAL: 2 Minute Static Stretching|BEHAVIORAL: 5 Minute Static Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 3 Days Versus 5 Days Amoxicillin for Chest-indrawing Childhood Pneumonia in Malawi
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Amoxicillin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TOP-Study (Tacrolimus Organ Perfusion): Treatment of Ischemia Reperfusion Injury in Marginal Organs With an ex Vivo Tacrolimus Perfusion
Status: TERMINATED
Conditions: Terminal Liver Disease|Ischemia Reperfusion Injury|Graft Dysfunction|Graft Failure|Poor Graft Quality
Interventions: DRUG: Tacrolimus|DRUG: HTK/Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Assessment of Surgical Margins Using Confocal Microscopy in Comparison With Reference Extemporaneous Examination
Status: RECRUITING
Conditions: Squamous Cell Carcinoma of Head and Neck|Basal Cell Carcinoma of Skin
Interventions: OTHER: microscopy confocal (Histolog Scanner)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
Status: NOT_YET_RECRUITING
Conditions: Amyloidosis|Amyloid Cardiomyopathy|Transthyretin Amyloidosis|Cardiomyopathies|Heart Diseases|Polyneuropathies
Interventions: DRUG: Acoramidis|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improving Posture in Parkinson's Patients Through Home-based Training and Biofeedback
Status: UNKNOWN
Conditions: Parkinson's Disease and Parkinsonism|Postural Kyphosis
Interventions: DEVICE: ambulatory use of the Upright device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Proof of Concept Study in Uncomplicated UTI
Status: UNKNOWN
Conditions: Urinary Tract Infections
Interventions: DRUG: MPC-SHRC|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vizol S Lipid Balance Efficacy and Safety Study in Patients With Dry Eye
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: Vizol S LIPID BALANCE eye drops|DRUG: ophthalmic saline eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Octreotide as Palliative Therapy for Cancer-Related Bowel Obstruction That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Colorectal Cancer|Constipation, Impaction, and Bowel Obstruction|Extrahepatic Bile Duct Cancer|Gastric Cancer|Gastrointestinal Stromal Tumor|Nausea and Vomiting|Ovarian Cancer|Pancreatic Cancer|Peritoneal Cavity Cancer|Small Intestine Cancer
Interventions: DRUG: octreotide acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: AZD3241 PET MSA Trial, Phase 2, Randomized,12 Week Safety and Tolerability Trial With PET in MSA Patients
Status: COMPLETED
Conditions: Multiple System Atrophy, MSA
Interventions: DRUG: AZD3241|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hormonal Outcomes in Acromegalic Patients With Treated Surgery With or Without Long Acting Somatostatin Analogues
Status: UNKNOWN
Conditions: Acromegaly
Interventions: DRUG: Sandostatin (Octreotide Acetate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dasatinib (BMS-354825) in Subjects With Lymphoid Blast Phase Chronic Myeloid Leukemia or Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia|Leukemia, Lymphoblastic, Acute, Philadelphia-positive
Interventions: DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Seroquel SR in the Treatment of Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: Quetiapine fumarate|DRUG: Paroxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: KONCERT A Kaletra ONCE Daily Randomised Trial of the Pharmacokinetics, Safety and Efficacy of Twice-daily Versus Once-daily Lopinavir/Ritonavir Tablets Dosed by Weight as Part of Combination Antiretroviral Therapy in Human Immunodeficiency Virus-1 (HIV-1) Infected Children (PENTA 18)
Status: COMPLETED
Conditions: Antiretroviral Therapy in HIV-1 Infected Children
Interventions: DRUG: Kaletra dosed once daily|DRUG: kaletra dosed twice daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability Of A Crizotinib Oral Liquid Formulation To Crizotinib Formulated Capsule
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Busulfan, Etoposide, and Intensity-Modulated Radiation Therapy Followed By Donor Stem Cell Transplant in Treating Patients With Advanced Myeloid Cancer
Status: TERMINATED
Conditions: Adult Acute Myeloid Leukemia in Remission|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Blastic Phase Chronic Myelogenous Leukemia|Childhood Acute Myeloid Leukemia in Remission|Childhood Chronic Myelogenous Leukemia|Childhood Myelodysplastic Syndromes|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Myeloid Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Refractory Anemia With Excess Blasts
Interventions: DRUG: busulfan|DRUG: etoposide|RADIATION: intensity-modulated radiation therapy|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: tomotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ERADICATE Hp - Treating Helicobacter Pylori With RHB-105
Status: COMPLETED
Conditions: Dyspepsia|Helicobacter Pylori Infection
Interventions: DRUG: RHB-105|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Treatment of Sleep Apnea on Metabolic Syndrome
Status: COMPLETED
Conditions: Impaired Glucose Tolerance|Obstructive Sleep Apnea
Interventions: DEVICE: Continuous Positive Airway Pressure (CPAP) (Philips-Respironics RemStar Pro® CPAP)|DEVICE: Sham-Continuous Positive Airway Pressure (CPAP) (Philips-Respironics)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Seasonal Allergic Rhinitis Treatment With 2 Antihistamines Used in Combination With Intranasal Corticosteroid
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Olopatadine HCl Nasal Spray, 0.6%|DRUG: Azelastine HCl Nasal Spray, 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trauma-Informed Sleep Intervention for Children in Foster Care
Status: RECRUITING
Conditions: Sleep Disturbance|Child Development|Mental Disorder, Child
Interventions: BEHAVIORAL: Bolstering Sleep and Adjustment in Foster Environments (B-SAFE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GVAX vs. Placebo for MDS/AML After Allo HSCT
Status: TERMINATED
Conditions: Myelodysplastic Syndrome|Acute Myeloid Leukemia|Chronic Myelomonocytic Leukemia
Interventions: BIOLOGICAL: GVAX|BIOLOGICAL: Placebo Vaccine|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplant|DRUG: Busulfan|DRUG: Fludarabine|DRUG: Tacrolimus|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Hair Follicle Derived Mesenchymal Stem Cell Suspension to Treat AGA
Status: COMPLETED
Conditions: Hair Transplantation
Interventions: OTHER: autologous hair follicle derived mesenchymal stem cell suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pyrotinib and Vinorelbine Tartrate Capsules With or Without Inetetamab for First Line Treatment in Patients With Trastuzumab-resistant HER2-positive Advanced Breast Cancer
Status: UNKNOWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Pyrotinib|DRUG: Vinorelbine|DRUG: Inetetamab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can E-cadherin Found in Tissue/Blood be Valuable in Identifying & Monitoring Patients With Post-proton Pump Inhibitor (PPI)-Responsive Heartburn
Status: COMPLETED
Conditions: Heartburn|Gastroesophageal Reflux Disease
Interventions: DRUG: Dexlansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect Insoles on Functional Capacity With Adolescent Idiopathic Scoliosis Using Spinal Orthosis
Status: COMPLETED
Conditions: Scoliosis; Adolescence|Pressure Area|Scoliosis|Orthosis
Interventions: DEVICE: Spinal Orthoses and Insoles|DEVICE: Spinal Orthoses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Evaluating the Effects of Electroacupuncture and Rosiglitazone Combined Therapy
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus With Features of Insulin Resistance
Interventions: OTHER: EA + Rosiglitazone|DRUG: TZD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Pegylated Human Recombinant Arginase for Liver Cancer
Status: COMPLETED
Conditions: Neoplasm|Hepatocellular Carcinoma
Interventions: BIOLOGICAL: Pegylated Recombinant Human Arginase I|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety of VX-152 Combination Therapy in Adults With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: VX-152|DRUG: TEZ/IVA|DRUG: IVA|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Donor Specific T Response Measurment for IS Minimization in de Novo Renal Transplantation
Status: COMPLETED
Conditions: Disorder Related to Renal Transplantation|Effects of Immunosuppressant Therapy
Interventions: DRUG: Tacrolimus (for Group B)|DRUG: MMF (mycophenolate mofetil) (for Group B)|DRUG: 6-methyl prednisolone (Steroids) (for Group B)|DRUG: Tacrolimus (for Group A)|DRUG: Mycofenolate mofetil (MMF) (for Group A)|DRUG: 6-methyl prednisolone (Steroids) (for Group A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Axitinib in1st Line Treatment for Patients With Advanced or Metastatic Papillary Renal Cell Carcinoma
Status: COMPLETED
Conditions: Papillary Renal Cell Carcinoma
Interventions: DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accuracy, Feasibility and Acceptance of CGM Lupus
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus|Critical Illness|Diabetic Blood Glucose Monitoring
Interventions: DEVICE: Flash glucose monitoring system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study to Investigate ANS014004 in Participants With Locally Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Locally Advanced or Metastatic Solid Tumors
Interventions: DRUG: ANS014004
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Granisetron Transdermal Patch for Prevention of Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: granisetron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positive Psychology for ACS Patients: a Factorial Design Study
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: OTHER: Positive Psychology (PP)|OTHER: Motivational Interviewing (MI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SWOG-9133 RT w/ or w/o Doxorubicin and Vinblastine in Stage I or Stage II Hodgkin's Disease
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: doxorubicin hydrochloride|DRUG: vinblastine|RADIATION: standard subtotal nodal irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ixazomib and Erlotinib in Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Ixazomib|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glivec in Ph Positive Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Cromosome Philadelphia Positive
Interventions: DRUG: chemotherapy|DRUG: Glivec
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Palliative Care for Patients With Haematological Malignancies
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome|Diffuse Large B Cell Lymphoma|Palliative Care
Interventions: DRUG: Early palliative care integration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Novel, Non-ischemic and Pain-free Exercise Intervention in Peripheral Artery Disease
Status: NOT_YET_RECRUITING
Conditions: Claudication|Peripheral Artery Disease
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention of Intestinal Microorganism in Mild Cognitive Impairment
Status: COMPLETED
Conditions: Gut Microbiota|Mild Cognitive Impairment|Dementia, Alzheimer Type|Neuroimaging
Interventions: DIETARY_SUPPLEMENT: Probiotic supplemented intervention|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Orexin on Delayed Emergence of General Anesthesia in Dexmedetomidine
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Dexmedetomidine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: 68Ga Citrate PET/MRI for Evaluation of Fever of Unknown Origin (FUO)
Status: WITHDRAWN
Conditions: Fever of Unknown Origin
Interventions: DRUG: 68Ga-Citrate PET/MRI|DRUG: 67Ga-Citrate SPECT|DEVICE: Positron Emission Tomography|DEVICE: Magnetic Resonance Imaging|DEVICE: SPECT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Influence of Chardonnay Marc Intake on Gut and Cardiometabolic Health
Status: RECRUITING
Conditions: Cardiovascular Diseases|Adiposity|Cardiometabolic Syndrome
Interventions: OTHER: Chardonnay Marc
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Improving Therapeutic Adherence With a Co-constructed Program Involving Both Patients and Health Care Professionals
Status: RECRUITING
Conditions: Cystic Fibrosis
Interventions: OTHER: " Information-Motivation-Behavioral skills " intervention.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH