pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clinical Trial in Patients Diagnosed With Immune Thrombocytopenic Purpura
Status: COMPLETED
Conditions: Immune (Idiopathic) Thrombocytopenic Purpura
Interventions: BIOLOGICAL: IGIV3I Grifols
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Immunotherapy in Rare Mutations Localized NSCLC
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer|RET Driver Mutation|BRAF V600 Mutation|Erb-B2 Receptor Tyrosine Kinase Exon 20 Mutation|MET Amplification|MET Exon 14 Skipping Mutation
Interventions: BIOLOGICAL: Toripalimab|DRUG: Nab paclitaxel|DRUG: Pemetrexed|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrafiltration Profiling and Outcomes Among Individuals on Maintenance Hemodialysis
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: OTHER: UF profiling during HD|OTHER: Conventional HD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of the Protein Matrix in the Anabolic Response to a Ground Beef Patty as Opposed to the Impossible (Vegi-) Burger
Status: COMPLETED
Conditions: Protein Metabolism
Interventions: OTHER: food: cooked 85% lean ground beef|OTHER: food: Impossible Burger (R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Outcomes Study of the Trabecular Metal (TM) Reverse Shoulder System
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis|Rheumatoid Arthritis|Post-traumatic Arthritis|Ununited Humeral Head Fracture|Irreducible 3-and 4-part Proximal Humeral Fractures|Avascular Necrosis|Gross Rotator Cuff Deficiency|Revision Total Shoulder Arthroplasty
Interventions: DEVICE: Trabecular Metal Reverse Shoulder System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I-II Trial of Sorafenib in Combination With Ifosfamide in Soft Tissue Sarcoma
Status: UNKNOWN
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Decision Support Tools to Increase Human Papillomavirus (HPV) Vaccination in Adolescents in Pharmacies
Status: RECRUITING
Conditions: Human Papillomavirus-Related Carcinoma
Interventions: OTHER: Discussion|OTHER: Educational Activity|BEHAVIORAL: Healthcare Activity|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Vaccine Therapy in Treating Patients With Advanced Melanoma
Status: COMPLETED
Conditions: Intraocular Melanoma|Malignant Conjunctival Neoplasm|Melanoma (Skin)
Interventions: BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: multi-epitope melanoma peptide vaccine|BIOLOGICAL: tetanus toxoid helper peptide|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of the Different Ways of Appendix Stump Closure on Patient Outcome in Laparoscopic Appendectomy
Status: COMPLETED
Conditions: Appendicitis
Interventions: PROCEDURE: E group|PROCEDURE: S group|PROCEDURE: H group|PROCEDURE: DS group|DEVICE: Endoloop|DEVICE: Stapler|DEVICE: Hem-o-lok clip|DEVICE: DS clip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Serotonin-norepinephrine Reuptake Inhibitors and Acute Kidney Injury
Status: COMPLETED
Conditions: Depression|Acute Kidney Injury
Interventions: DRUG: Duloxetine|DRUG: Venlafaxine|DRUG: Desvenlafaxine|DRUG: Citalopram|DRUG: Escitalopram|DRUG: Fluoxetine|DRUG: Fluvoxamine|DRUG: Paroxetine|DRUG: Sertraline
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Detection of Advanced Adenomas and Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer|Colorectal Neoplasms|Colorectal Polyp|Colorectal Adenocarcinoma|Colorectal Disorders|Colorectal Dysplasia|Colorectal Cancer Stage I|Colorectal Cancer Stage II|Colorectal Cancer Stage III|Colorectal Cancer Stage IV|Colorectal Neoplasms Malignant|Colorectal Serrated Adenocarcinoma|Colorectal Adenoma With Severe Dysplasia|Colorectal Adenoma With Mild Dysplasia|Colorectal Adenoma With Moderate Dysplasia|Colorectal Adenoma and Carcinoma 1|Colorectal Adenomatous Polyp|Colorectal Adenocarcinoma Metastatic in the Liver
Interventions: DIAGNOSTIC_TEST: DENEB
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Closure Method Study Following Tonsillectomy in Children
Status: COMPLETED
Conditions: Tonsillectomy|Children
Interventions: PROCEDURE: Closure of the Tonsillar Fossa|PROCEDURE: Tonsillectomy with open fossa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Cagrilintide|DRUG: Semaglutide|DRUG: Placebo cagrilintide|DRUG: Placebo semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ARV-766 Given by Mouth in Men With Metastatic Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer Metastatic
Interventions: DRUG: ARV-766 Part A&B|DRUG: ARV-766 + Abiraterone Part C&D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Comparison of Methadone, Fentanyl, and Morphine for Post-laparotomy Epidural Analgesia
Status: COMPLETED
Conditions: Post Laparotomy Pain Treatment
Interventions: DRUG: epidural morphine via PCEA|DRUG: epidural fentanyl via PCEA|DRUG: epidural methadone via PCEA|DRUG: intravenous morphine via PCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A SkeleTal Muscle Recovery Intervention With Dietary Protein in Heart Failure
Status: RECRUITING
Conditions: Heart Failure|Muscle Atrophy
Interventions: DIETARY_SUPPLEMENT: Ensure Max Protein|DIETARY_SUPPLEMENT: Ensure Original
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Potentiation of the Effects of Prismatic Adaptation by Transcranial Direct Current Stimulation (tDCS) : Evaluation of Functional Interest in Negligence Rehabilitation
Status: COMPLETED
Conditions: Neurologic Neglect Syndrome
Interventions: DEVICE: transcranial direct current stimulation (tDCS)|DEVICE: Control: placebo stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Insecticidal School Uniforms for Dengue Prevention in Thailand
Status: TERMINATED
Conditions: Dengue
Interventions: OTHER: permethrin insecticide|OTHER: washing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of TUDCA on Endothelial Function in Type 2 DM
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2|Insulin Response|Endothelial Dysfunction
Interventions: DIETARY_SUPPLEMENT: Tauroursodeoxycholic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Point Of Care Ultrasound For Prediction Of Fluid Responsiveness in Off Pump Coronary Artery Bypass Grafting Surgery
Status: NOT_YET_RECRUITING
Conditions: Prevention of Hypotension
Interventions: PROCEDURE: Inferior vena cava diameter measurement by ultrasonography|PROCEDURE: difference between peak velocities of carotid artery by ultrasound|PROCEDURE: cardiac output be transthoracic echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Gonadotropin Replacement Therapy on Metabolic Parameters in Patients With Hypogonadism
Status: COMPLETED
Conditions: Idiopathic Hypogonadotropic Hypogonadism
Interventions: DRUG: human chorionic gonadotropin, human menopausal gonadotropin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDS
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Primaquine|DRUG: Sulfamethoxazole-Trimethoprim|DRUG: Dapsone|DRUG: Clindamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Intraprocedural Assessment of Ablation Margins Using Computed Tomography Co-registration in Primary Liver Tumor Treatment With Percutaneous Ablation
Status: COMPLETED
Conditions: HCC
Interventions: DIAGNOSTIC_TEST: Additional intraprocedural pre-ablation CT-scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cervical Proprioceptive Neuromuscular Facilitation and Stabilization Exercises in Stroke Patients
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: PNF+ biofeedback exercise group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxycodone Extended-release in the Treatment of Perioperative Pain in Patients Undergoing Orthopaedic Surgery
Status: COMPLETED
Conditions: Surgery
Interventions: DRUG: Extended-release oxycodone|DRUG: Extended- release Oxycodone|DRUG: ketoprofen|DRUG: dipirone|DRUG: dexametasone|DRUG: Morphine IV (rescue)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ablation Combined With PD-1 in HCC: Phase II Study
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: PD-1 monoclonal antibody|PROCEDURE: Radiofequencey or microwave ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Dialogue Study: A Virtual-reality Based Treatment for Eating Disorders
Status: RECRUITING
Conditions: Eating Disorders|Anorexia Nervosa|Bulimia Nervosa
Interventions: BEHAVIORAL: Virtual-reality intervention|BEHAVIORAL: TAU - specialized treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glucocorticoids for Post-operative Patients With Acute Type A Aortic Dissection (The GLAD Trial)
Status: COMPLETED
Conditions: Methylprednisolone|Glucocorticoid|Aortic Dissection|Organ Dysfunction
Interventions: DRUG: Methylprednisolone Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Advancing Rehabilitation Paradigms for Older Adults in Skilled Nursing Facilities
Status: RECRUITING
Conditions: Aging|Functional Recovery|Skilled Nursing Facility|Medically Complex|Deconditioning
Interventions: OTHER: i-STRONGER|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: L-NMMA Dose-response Study in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: NG-monomethyl-L-arginine (L-NMMA)|DRUG: NG-monomethyl-L-arginine (L-NMMA)|DRUG: NG-monomethyl-L-arginine (L-NMMA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Liver Transplantation With Tregs at UCSF
Status: TERMINATED
Conditions: Liver Transplant
Interventions: BIOLOGICAL: arTreg|PROCEDURE: leukapheresis|DRUG: cyclophosphamide|DRUG: mesna|DRUG: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Exercise Effects on Cognitive Processing Speed in Multiple Sclerosis: A Pilot Trial
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Remotely Delivered and Supported Aerobic Walking Exercise Training|BEHAVIORAL: Remotely Delivered and Supported Stretching and Toning Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Investigate the Safety and Efficacy of DE-104 Ophthalmic Solution to Treat Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: DE-104 ophthalmic solution|DRUG: DE-104 vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Comparative Study Of Pregabalin And Gabapentin As Adjunctive Therapy In Subjects With Partial Seizures
Status: COMPLETED
Conditions: Epilepsy|Partial Seizure Disorder|Epilepsies, Partial|Complex Partial Seizure Disorder
Interventions: DRUG: Pregabalin|DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study to Evaluate the Efficacy and the Safety of Flumatinib in CML-AP or CML-BP Patients
Status: UNKNOWN
Conditions: Chronic Myelogenous Leukemia
Interventions: DRUG: Flumatinib mesylate tablet 600 mg qd
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PSMA PET/MRI or PSMA PET/CT for Evaluation of Liver Cancer
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Computed Tomography|DRUG: Gallium Ga 68 Gozetotide|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Drug-drug Interaction Study of AJU-A51R1 and AJU-A51R2
Status: COMPLETED
Conditions: T2DM (Type 2 Diabetes Mellitus)
Interventions: DRUG: Treatment A|DRUG: Treatment B|DRUG: Treatment C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Contact Insole for Chronic Nonspecific Low Back Pain (LBP)
Status: COMPLETED
Conditions: Chronic Nonspecific Low Back Pain
Interventions: DEVICE: Total Contact Insole|DEVICE: Ethyl vinyl acetate flat insole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TEE as a Guide for Fluid Optimization in Major Abdominal Oncosurgery
Status: COMPLETED
Conditions: Fluid Therapy
Interventions: OTHER: TEE guided fluid therapy will be administered|OTHER: Stroke volume variation guided intravenous fluid.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of a Pluriprofessional Intervention to Improve Medication Adherence (Secondary Preventive Medication) in Patients After Ischemic Stroke
Status: UNKNOWN
Conditions: Ischemic Stroke
Interventions: BEHAVIORAL: Pharmaceutical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Treat Patients With Edentulous Mandibles With Two Straumann 3.3mm Diameter Bone Level Implants
Status: COMPLETED
Conditions: Jaw, Edentulous
Interventions: DEVICE: Titanium Zircon implant|DEVICE: Titanium Grade IV implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: KYleena Satisfaction Study / Observational Study on User Satisfaction With the Levonorgestrel Intrauterine Delivery System Kyleena (LNG-IUS 12) in New Contraceptive Users and After Switching From Another Contraceptive Method
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Kyleena
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SX-682 and Nivolumab for the Treatment of RAS-Mutated, MSS Unresectable or Metastatic Colorectal Cancer, the STOPTRAFFIC-1 Trial
Status: RECRUITING
Conditions: Metastatic Colon Adenocarcinoma|Metastatic Colorectal Carcinoma|Metastatic Rectal Adenocarcinoma|Stage III Colon Cancer AJCC v8|Stage III Rectal Cancer AJCC v8|Stage IIIA Colon Cancer AJCC v8|Stage IIIA Rectal Cancer AJCC v8|Stage IIIB Colon Cancer AJCC v8|Stage IIIB Rectal Cancer AJCC v8|Stage IIIC Colon Cancer AJCC v8|Stage IIIC Rectal Cancer AJCC v8|Stage IV Colon Cancer AJCC v8|Stage IV Rectal Cancer AJCC v8|Stage IVA Colon Cancer AJCC v8|Stage IVA Rectal Cancer AJCC v8|Stage IVB Colon Cancer AJCC v8|Stage IVB Rectal Cancer AJCC v8|Stage IVC Colon Cancer AJCC v8|Stage IVC Rectal Cancer AJCC v8|Unresectable Colon Adenocarcinoma|Unresectable Rectal Adenocarcinoma
Interventions: DRUG: CXCR1/2 Inhibitor SX-682|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Foot Orthoses in Patients With Sciatica
Status: RECRUITING
Conditions: Chronic Sciatica|Foot Deformity
Interventions: DEVICE: Custom-made foot orthosis|DEVICE: Placebo orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Topical Pharyngeal Anesthetics on Discharge of the Patients When Used in Conjunction With Propofol Sedation in Routine EGD's
Status: COMPLETED
Conditions: Topical Anesthesia
Interventions: DRUG: Lidocaine|DRUG: Placebo|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib and Lenalidomide for Patients With Myelofibrosis
Status: COMPLETED
Conditions: Myeloproliferative Diseases
Interventions: DRUG: Ruxolitinib|DRUG: Lenalidomide|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Safety and Efficacy of BMMNC for the Patient With Duchenne Muscular Dystrophy
Status: UNKNOWN
Conditions: Muscular Dystrophy|Duchenne Muscular Dystrophy
Interventions: OTHER: Intralesional/ Intravenous of Autologous Stem cells.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Automating Peer Learning to Reduce Alcohol Use and Related Deviant Behavior in Secondary School
Status: COMPLETED
Conditions: Substance Use|Stress|Relation, Interpersonal|Bullying|Victimisation|Mental Health Issue|Sleep, Inadequate|Social Skills
Interventions: BEHAVIORAL: PeerLearning.net
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Efficacy of Advanced and Traditional Wound Dressings in Post-Operative Orthopedic Care
Status: COMPLETED
Conditions: Orthopaedics Wound Dressings
Interventions: DEVICE: Aquacel Ag|DEVICE: OPSITE|DEVICE: MEPILEX POST OP BORDER|DEVICE: Traditional Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Pomalidomide, Oral Dexamethasone and Ixazomib in Patients With Relapsed MM Who Have Received Lenalidomide
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Drug: Ixazomib Drug:pomalidomide Drug:dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zimmer Trabecular Metal Total Ankle PMCF
Status: ACTIVE_NOT_RECRUITING
Conditions: Degenerative Arthritis|Rheumatoid Arthritis|Post Traumatic Arthritis
Interventions: DEVICE: Zimmer Trabecular Metal Total Ankle System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proton Beam Teletherapy for Post-Hysterectomy Cancers of the Uterus and Cervix
Status: UNKNOWN
Conditions: Uterine Cancer|Cervical Cancer
Interventions: RADIATION: Proton radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep Apnea Study in Adults Using DreamPort-Eclipse and a Traditional Nasal Mask
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Eclipse novel CPAP mask|DEVICE: ResMed P-10 mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relation of Caries Color to Caries Severity and Its Microbial Load
Status: ACTIVE_NOT_RECRUITING
Conditions: Relation of Caries Color
Interventions: OTHER: Black color of caries|OTHER: dark brown color of caries|OTHER: light brown color of caries|OTHER: yellow color of caries
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prevention of Type II Endoleaks During Endovascular Treatment of Abdominal Aortic Aneurysm: Endovascular Treatment Versus Combination With Coil Embolisation of the Aneurysmal Sac
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm
Interventions: PROCEDURE: EVAR without coils embolization/ Coils embolization during EVAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Bioavailability of a New Formulation of Pterostilbene Cocrystal in Comparison With Its Free Form (BIOPTERO2)
Status: COMPLETED
Conditions: Biological Availability
Interventions: DIETARY_SUPPLEMENT: Pterostilbene cocrystal (ccPT) - Gelatin capsule|DIETARY_SUPPLEMENT: Pterostilbene free form (PT)|DIETARY_SUPPLEMENT: Pterostilbene cocrystal (ccPT) - Gastro-resistant capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Vorinostat Plus Hydroxychloroquine Versus Regorafenib in Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Vorinostat|DRUG: Hydroxychloroquine|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Game Technology in the Early Diagnosis of Mild Cognitive Impairment and Alzheimer's Disease
Status: NOT_YET_RECRUITING
Conditions: Dementia Alzheimers
Interventions: DEVICE: G:DATA, dementia screen videogame
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Effects of Pulmonary Physiotherapy Treatments on Patients With COVID-19
Status: COMPLETED
Conditions: Covid-19|Pneumonia|SARS Pneumonia
Interventions: OTHER: Pulmonary Physiotherapy Techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of ET-743 (Trabectedin) in Patients With Persistent or Recurrent Endometrial Carcinoma
Status: COMPLETED
Conditions: Endometrial Neoplasms|Uterine Neoplasms|Genital Neoplasms, Female Urogenital Neoplasms
Interventions: DRUG: Trabectedin|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dermacyte® Amniotic Wound Care Liquid for the Treatment of Non-Healing Venous Stasis Ulcers
Status: RECRUITING
Conditions: Venous Stasis Ulcer|Venous Leg Ulcer
Interventions: BIOLOGICAL: Dermacyte® Liquid (human amniotic fluid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study to Compare the Benefits of Endoscopic Tumor Clip Placement and 3T-MRI Simulation for Accurate Target Volume Definition for Rectal Cancer Patients Undergoing Pre-operative Chemoradiation
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative the Effect of Metformin and Acupuncture on Weight Loss and Insulin Sensitivity
Status: COMPLETED
Conditions: Insulin Sensitivity|Obesity
Interventions: DRUG: metformin|OTHER: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use Of FFR Guided PCI Versus Complete Revascularization and Treatment Of Infarct Related Artery Only In Patients With STEMI
Status: UNKNOWN
Conditions: Multivessel Coronary Artery Disease|STEMI|FFR Guided PCI
Interventions: PROCEDURE: FFR guided PCI|PROCEDURE: Angio guided PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Escalating Doses of PM01183 in Combination With Fixed Doxorubicin in Patients With Specific Advanced Unresectable Solid Tumors
Status: COMPLETED
Conditions: Endometrial Adenocarcinomas|Neuroendocrine Tumors|Small-cell Lung Cancer With Less Than 2 Prior Cytotoxic-containing Lines of Therapy
Interventions: DRUG: lurbinectedin (PM01183)|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Clinical and Radiological Outcomes in Patients Undergoing Fixation of Osteochondral Fragments With Reasorbable Screws in the Knee Joint
Status: NOT_YET_RECRUITING
Conditions: Osteochondral Defect|Osteochondritis Dissecans|Osteochondral Fracture|Osteochondral Fracture of Patella
Interventions: PROCEDURE: Fixation of osteochdral fragments with reabsorbable screws
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acute Effects of Waterpipe Smoking on Cognitive Measures and Cardiorespiratory Parameters
Status: COMPLETED
Conditions: Waterpipe Smoking
Interventions: DIAGNOSTIC_TEST: The Digit span test and PASAT with waterpipe smoking|DIAGNOSTIC_TEST: The Digit span test and PASAT without waterpipe smoking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mitigating the Impact of Shoulder Movement Dysfunction; a Randomized Controlled Trial
Status: COMPLETED
Conditions: Shoulder Injuries|Shoulder Pain
Interventions: PROCEDURE: Active Rehabilitation Program (ARP)|PROCEDURE: Nonspecific Passive Intervention (NPI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Cognitive Deficits in Traumatic Spinal Cord Injury (SCI)
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: BEHAVIORAL: Behavorial; memory exercise|BEHAVIORAL: Placebo; memory exercise|BEHAVIORAL: Behavioral: speed exercises|BEHAVIORAL: Placebo speed training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Determine the Effect of Food on the Pharmacokinetics of Olaparib and the Effect of Olaparib on QT Interval Following Oral Dosing of a Tablet Formulation in Patients With Advanced Solid Tumours
Status: COMPLETED
Conditions: Solid Tumours
Interventions: DRUG: Olaparib tablets|PROCEDURE: Pharmacokinetic sampling|OTHER: Dietary Fasted|OTHER: Dietary High Fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Recurrence Risk Factors in Locally Advanced Breast Cancer Patients Underwent Neoadjuvant Chemotherapy.
Status: RECRUITING
Conditions: Breast Cancer|Chemotherapy Effect|Triple Negative Breast Cancer|Recurrence, Local Neoplasm|Risk Factors
Interventions: DIAGNOSTIC_TEST: MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Lateral Wedge Insole for Knee Osteoarthritis Patient in Plantar Pressure, Quadriceps Thickness, Gait and Walking Speed
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Lateral wedge insole|OTHER: Ordinary insole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combined Surgery in Management of Congenital Pseudarthrosis of Tibia
Status: RECRUITING
Conditions: Congenital Pseudarthrosis of Tibia
Interventions: DEVICE: llizarov external fixation device|DEVICE: intramedullary rod fixation|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mandibular Advancement Device (MAD) in Pregnant Women With Obstructive Sleep Apnea (OSA)
Status: RECRUITING
Conditions: Obstructive Sleep Apnea of Adult|Pregnancy Related
Interventions: DEVICE: Mandibular advancement Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Turkish Version of the Musculoskeletal Pain Intensity and Interference Questionnaire for Musicians (MPIIQM-T)
Status: UNKNOWN
Conditions: Musculoskeletal Pain|Questionnaire
Interventions: OTHER: The groups evaluated by The Musculoskeletal Pain Intensity and Interference Questionnaire for Professional Orchestra Musicians, Brief Pain Inventory, QuickDASH and Fatigue Severity Scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioequivalence Study of Torrent Pharmaceuticals Ltd's Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Torrent's Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: A Study to Determine Dose and Regimen of Durvalumab as Monotherapy or in Combination With Pomalidomide With or Without Dexamethasone in Subjects With Relapsed and Refractory Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Durvalumab|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Helfer Skin Tap Technique During Tetanus Injection in Pregnant Women
Status: COMPLETED
Conditions: Intramuscular Injection|Pain
Interventions: PROCEDURE: Helfer skin tap injection technique|PROCEDURE: Standard Injection technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Long-term Outcome of N-Carbamylglutamate Treatment in Propionic Acidemia and Methylmalonic Acidemia
Status: TERMINATED
Conditions: Propionic Acidemia|Methylmalonic Acidemia
Interventions: DRUG: N-carbamylglutamate|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Venous Thromboembolism (VTE) Treatment Study in Japanese Deep Vein Thrombosis (DVT) Patients
Status: COMPLETED
Conditions: Deep Vein Thrombosis
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Unfractionated heparin|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Reduction of Abdominal Fat Utilizing the CoolFlex and eZ App 6.3 Applicators
Status: COMPLETED
Conditions: Fat Reduction in the Abdomen
Interventions: DEVICE: The Zeltiq System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Impact on Ovarian Reserve of Ovarian Cystectomy Versus Laser Vaporization in the Treatment of Ovarian Endometrioma: a Randomized Clinical Trial
Status: UNKNOWN
Conditions: Endometrioma
Interventions: PROCEDURE: stripping technique|DEVICE: CO2 laser (AcuPulse Duo, Lumenis)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Patient Reported Outcome Measures Using the BREAST-Q Questionnaire in Patients Undergoing Pre Versus Sub-pectoral Implant Based Immediate Breast Reconstruction.
Status: UNKNOWN
Conditions: Breast Disease|Breast Cancer|Patient Satisfaction|Surgery
Interventions: PROCEDURE: Pre- or sub-pectoral implant based immediate breast reconstruction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Profile of Soluble and Cellular Biomarkers and of Functional Imaging During Antiangiogenic Therapies in Cancer Patients
Status: TERMINATED
Conditions: Hepatocellular Cancer|Non-small Cell Lung Cancer|Renal Cell Cancer|Colorectal Cancer
Interventions: DRUG: Avastin|DRUG: Suntent|DRUG: Nexavar
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate Safety and Efficacy of Revanesse® Ultra + vs Revanesse® Ultra for Correction of NLF
Status: COMPLETED
Conditions: Nasolabial Fold Correction
Interventions: DEVICE: Revanesse Ultra+ (with lidocaine)|DEVICE: Revanesse Ultra
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Washington Study of Hemofiltration After Out-of-Hospital Cardiac Arrest
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: OTHER: Standard Care|DEVICE: Low Volume Hemofiltration|DEVICE: High Volume Hemofiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Optic Capture Without Anterior Vitrectomy in Pediatric Cataract Surgery
Status: COMPLETED
Conditions: Cataract, Juvenile
Interventions: PROCEDURE: optic capture|PROCEDURE: In-the-bag implantation of Intraocular lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors
Status: RECRUITING
Conditions: Breast Carcinoma|Malignant Solid Neoplasm|NUT Carcinoma
Interventions: DRUG: Abemaciclib|DRUG: BET Bromodomain Inhibitor ZEN-3694|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Diagnostic Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of a Therapeutic DNA Dendritic Cell Vaccine in HIV-Infected Children, Adolescents, and Young Adults
Status: WITHDRAWN
Conditions: HIV Infections
Interventions: BIOLOGICAL: DermaVir patch|BIOLOGICAL: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Multimodal Educational Intervention to Improve Adherence to Treatment Regimens in Older Stroke Patients
Status: UNKNOWN
Conditions: Stroke|Medication Adherence|Older Adults
Interventions: BEHAVIORAL: Patient-based intervention|BEHAVIORAL: Family based intervention|OTHER: Routine counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Building Individual and Community Resilience Through Nature-based Therapies - Case Study 8 Nature for All
Status: NOT_YET_RECRUITING
Conditions: Mobility Disability
Interventions: BEHAVIORAL: Audioguided Nature tour|BEHAVIORAL: Non audio guided nature tour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Intravenous Caffeine on Atrial Electrical Properties and Potential Arrythmia Induction
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: OTHER: Intravenous caffeine|OTHER: Masked Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Effects of RO7496998 (AT-527) in Non-Hospitalized Adult and Adolescent Participants With Mild or Moderate COVID-19
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: RO7496998|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of JV-213 Autologous CD79b-targeting Chimeric Antigen Receptor T-cell Therapy in Adults With Relapsed or Refractory B-cell Lymphomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphomas|B-cell Lymphomas
Interventions: DRUG: JV-213|PROCEDURE: Leukapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Clinical Trial of Buagafuran Capsules in the Treatment of GAD
Status: RECRUITING
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: Buagafuran capsules, 15mg/ capsule|DRUG: Buagafuran capsules mimic, 0mg/ capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Peritoneal Dialysis Decreases Time to Achieve a Negative Fluid Balance After the Norwood Procedure
Status: COMPLETED
Conditions: Hypoplastic Left Heart Syndrome
Interventions: DEVICE: Peritoneal dialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia
Status: COMPLETED
Conditions: Critical Limb Ischemia
Interventions: BIOLOGICAL: Low Dose VM202|BIOLOGICAL: High Dose VM202|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Toripalimab Injection in the Treatment of Recurrent or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Who Have Failed at Least Two Prior Lines of Therapy and Are Positive Specific Markers
Status: UNKNOWN
Conditions: Recurrent or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Who Have Failed at Least Two Prior Lines of Therapy
Interventions: DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pharmacokinetics, Efficacy, and Safety of a Recombinant and Protein-Free Factor VIII (rAHF-PFM) in Pediatric Patients With Hemophilia A
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: Antihemophilic factor, recombinant, manufactured protein-free
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Fiberoptic Intubation With Fiberoptic Intubation Through an Air-Q Intubating Laryngeal Airway in Infants and Small Children
Status: COMPLETED
Conditions: Fiberoptic Intubation in Children
Interventions: DEVICE: air-Q, followed by fiberoptic intubation|DEVICE: Free-hand Fiberoptic Intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Study to Evaluate a 13-valent Pneumococcal Conjugate Vaccine in Infants.
Status: COMPLETED
Conditions: Vaccines, Pneumococcal
Interventions: BIOLOGICAL: 13-valent pneumococcal conjugate vaccine|BIOLOGICAL: 7-valent pneumococcal conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Chidamide, Decitabine and Immune Checkpoint Inhibitors in R/R NHL and Advanced Solid Tumors
Status: RECRUITING
Conditions: Relapsed/Refractory Non-Hodgkin Lymphoma|Advanced Solid Tumors
Interventions: DRUG: Chidamide|DRUG: Decitabine|DRUG: Immune checkpoint inhibitors（anti-PD1/PD-L1/CTLA4 antibodies）
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aspiration Pneumonia in Cerebrovascular Stroke Patients Suffering From Bulbar Palsy
Status: RECRUITING
Conditions: Aspiration Pneumonia
Interventions: OTHER: Enteral nutrtion|OTHER: TPN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prime-boost Immunotherapeutic Trial in Men With Biochemical Recurrence After Definitive Local Therapy for Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: ChAdOx1-PCAQ|BIOLOGICAL: MVA-PCAQ
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS to Improve Cognitive Function in TBI
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DEVICE: rTMS|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ocular and Palpebral Manifestations of Mastocytosis (MOOMA)
Status: COMPLETED
Conditions: Mast Cell Activation Disease|Mast Cell Activation Syndrome|Mast Cell Disease|Urticaria Pigmentosa
Interventions: OTHER: Ophthalmological examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Proximal Contact Tightness and Location in Class II Composite Restorations
Status: COMPLETED
Conditions: Tooth Decay
Interventions: OTHER: Precontoured sectional matrix EZ COAT|OTHER: PerForm™|OTHER: AdDent Trimax™|OTHER: Contact Pro™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Developing a Mobile Method to Measure THC-induced Impairment
Status: COMPLETED
Conditions: Measuring THC-induced Cognitive Impairment Using a Mobile Application
Interventions: DRUG: Dronabinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy Extension Study of Daclizumab High Yield Process (DAC HYP) in Participants With Multiple Sclerosis Who Have Completed Study 205MS201 (NCT00390221) to Treat Relapsing-Remitting Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: BIOLOGICAL: BIIB019 (Daclizumab High Yield Process)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Comprehensive Nutrition Support Product on the Nutritional Status of Adults With Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Colitis, Ulcerative|Crohn's Disease
Interventions: OTHER: Nutrition support product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I, Dose Escalation Study to Evaluate the Safety and Pharmacokinetics of NTM-1632
Status: COMPLETED
Conditions: Botulism
Interventions: BIOLOGICAL: NTM-1632|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Dosimetry Study of 177Lu-LNC1004 Injection
Status: RECRUITING
Conditions: Solid Tumor, Unspecified, Adult
Interventions: DRUG: 177Lu-LNC1004 Injection group 1 radionuclide therapy|DRUG: 177Lu-LNC1004 Injection group 2 radionuclide therapy|DRUG: 177Lu-LNC1004 Injection group 3 radionuclide therapy|DRUG: 177Lu-LNC1004 Injection group 4 radionuclide therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT