pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pilot Study of Ranibizumab With and Without Ketorolac Eyedrops for Exudative Age-related Macular Degeneration
Status: COMPLETED
Conditions: Wet Macular Degeneration
Interventions: DRUG: Ketorolac + Ranibizumab|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Metabolism Observed at 7 Tesla
Status: RECRUITING
Conditions: Glut1 Deficiency Syndrome 1|Glucose Metabolism Disorders|Epilepsy|Glut1 Deficiency Syndrome 1, Autosomal Recessive|Glucose Transporter Type 1 Deficiency Syndrome|Glucose Transporter Protein Type 1 Deficiency Syndrome|Glucose Transport Defect
Interventions: DEVICE: Magnetic resonance imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pelvic External Combined With 252-Cf Neutron Intracavitary Radiotherapy With or Without Platinum in Treating Advanced Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer|Complications
Interventions: DRUG: Nedaplatin|RADIATION: Pelvic External Radiotherapy|RADIATION: 252-Cf Neutron Intracavitary Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain, Nutrition and Glycemic Response in Chronic Low Back Pain and Breast Cancer Survivors
Status: COMPLETED
Conditions: Chronic Pain
Interventions: OTHER: Low glycemic load|OTHER: High glycemic load
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Endoscopic Band Ligation Vs APC in Management of GAVE
Status: UNKNOWN
Conditions: GAVE - Gastric Antral Vascular Ectasia
Interventions: PROCEDURE: argon plasma coagulation|PROCEDURE: endoscopic band ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized One-Center Controlled Trial on a Comprehensive Nutritional Intervention for Children With Cerebral Palsy and ASD
Status: NOT_YET_RECRUITING
Conditions: Nutrition Disorder, Child
Interventions: BEHAVIORAL: Nutrilect
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Study of the Effect of Fractional co2 Laser Versus Q Switched:NdYAG Laser in the Treatment of Acanthosis Nigricans
Status: UNKNOWN
Conditions: Acanthosis Nigricans
Interventions: DEVICE: co2 laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Genoidentical Stem Cell Transplantation in Children With Sickle-cell Anemia and Cerebral Vasculopathy
Status: COMPLETED
Conditions: Sickle Cell Anemia|Cerebrovascular Accident
Interventions: PROCEDURE: Stem cell transplantation|PROCEDURE: Transfusion program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Regorafenib Study to Evaluate Cardiovascular Safety Parameters, Tolerability, and Anti-tumor Activity
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Regorafenib (Stivarga, BAY73-4506)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BLASST-1 (Bladder Cancer Signal Seeking Trial): Nivolumab, Gemcitabine, and Cisplatin in Treatment of Muscle Invasive Bladder Cancer (MIBC) Undergoing Cystectomy
Status: COMPLETED
Conditions: Muscle Invasive Bladder Cancer
Interventions: DRUG: Nivolumab|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Ovarian Follicular Activity and Hormone Levels for DR-102 Compared to Two 28-Day Oral Contraceptives
Status: COMPLETED
Conditions: Follicle Development|Ovarian Follicle|Follicle Count|Follicle Size|Oral Contraceptive
Interventions: DRUG: Desogestrel/ethinyl estradiol and ethinyl estradiol|DRUG: 28-day drospirenone oral contraceptive|DRUG: 28-day levonorgestrel oral contraceptive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Flax Mucilage and Apparent Nutrient Digestibility
Status: UNKNOWN
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: fiber drink and fiber bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of QLF32101 in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia and Myelodysplastic Syndrome
Interventions: DRUG: QLF32101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NIBS Therapy in Subacute Spinal Cord Injury
Status: NOT_YET_RECRUITING
Conditions: Traumatic Spinal Cord Injury|Tetraplegia/Tetraparesis
Interventions: DEVICE: Active rTMS|DEVICE: sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IMPACT: Safety and Feasibility of a Single-stage Procedure for Focal Cartilage Lesions of the Knee.
Status: COMPLETED
Conditions: Foreign-Body Reaction|Inflammation|Effusion (L) Knee|Knee Pain Swelling
Interventions: OTHER: Cartilage repair surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of Ranitidine Hydrochloride (Maximum Strength ZANTAC 150®) Compared to Two Different 150 mg Ranitidine Hydrochloride Oral Disintegrating Tablet (ODT) in Fasting, Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ranitidine hydrochloride ODT|DRUG: Ranitidine hydrochloride ODT RM|DRUG: Ranitidine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene)
Status: RECRUITING
Conditions: Neoplasm Metastasis|Non-Small Cell Lung Cancer
Interventions: DRUG: zongertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safest Choice of Antihypertensive Regimen for Postpartum Hypertension
Status: RECRUITING
Conditions: Postpartum Complication|Maternal Hypertension|High Blood Pressure
Interventions: DRUG: Oral Nifedipine|DRUG: Oral Labetalol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PENG vs FICB for Hip Fracture in ED Patients
Status: RECRUITING
Conditions: Femoral Neck Fractures|Intertrochanteric Fractures
Interventions: PROCEDURE: PENG|PROCEDURE: FICB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PET/MRI Scan for the Evaluation of Resectable Stage IA1-IB3 Cervical Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage IA Cervical Cancer|Stage IA1 Cervical Cancer|Stage IA2 Cervical Cancer|Stage IB Cervical Cancer|Stage IB1 Cervical Cancer|Stage IB2 Cervical Cancer|Stage IB3 Cervical Cancer
Interventions: OTHER: Fludeoxyglucose F-18|DRUG: Gadobutrol|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: DDI Study of Single Oral Dose of Acoziborole With Sequential Co-administration of Midazolam and Dextromethorphan
Status: COMPLETED
Conditions: Trypanosomiasis, African
Interventions: DRUG: Acoziborole|DRUG: Midazolam|DRUG: Dextromethorphan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Usefulness of Balanced High Protein Supplementation on Recovery and Clinical Outcomes After Chemotherapy
Status: RECRUITING
Conditions: Colorectal Neoplasms
Interventions: OTHER: ONS_320275|OTHER: ONS_211567
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Improving Access to Surgical Care: Safety, Efficacy, and Satisfaction With Postoperative Telehealth
Status: NOT_YET_RECRUITING
Conditions: Surgery
Interventions: OTHER: Telehealth follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cytogam Administration in Abdominal Organ Transplant Recipients at High Risk for Cytomegalovirus Infection
Status: COMPLETED
Conditions: Cytomegalovirus Disease
Interventions: DRUG: Valganciclovir|BIOLOGICAL: CMV hyperimmune globulin|DRUG: Valganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Lansoprazole on Sitagliptin Glucose-lowering Ability in Healthy Males: a Randomised Crossover Study
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: lansoprazole, 30 mg per day for 6 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Intralesional Vitamin D3 Versus Intralesional Acyclovir in Treatment of Plantar Warts
Status: UNKNOWN
Conditions: Plantar Wart
Interventions: DRUG: Vitamin D|DRUG: acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduced Intensity Conditioning Allogeneic Hematopoietic Stem Cell Transplant (HSCT) For Lymphoma
Status: WITHDRAWN
Conditions: Lymphoma
Interventions: PROCEDURE: Allogeneic stem cell transplantation|DRUG: Fludarabine|DRUG: Thiotepa|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sirolimus-eluting Stents With Biodegradable Polymer Versus an Everolimus-eluting Stents
Status: COMPLETED
Conditions: Coronary Artery Disease|Angina Pectoris|Myocardial Infarction
Interventions: DEVICE: Sirolimus-eluting stent with a bioresorbable polymer (Orsiro)|DEVICE: Everolimus-eluting stent with a durable polymer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of an Isotonic Balanced Fluid, Sterofundin® , With 0.9% Saline in Traumatic Brain Injury(TBI)
Status: UNKNOWN
Conditions: Brain Injuries
Interventions: PROCEDURE: Sterofundin|PROCEDURE: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of LPI on Different Sites of Iris
Status: UNKNOWN
Conditions: Glaucoma
Interventions: PROCEDURE: Corneoscleral limbus group|PROCEDURE: one spot group|PROCEDURE: two spots group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Equivalence Study of Generic Brinzolamide vs Azopt
Status: COMPLETED
Conditions: Glaucoma|Open Angle or Ocular Hypertension
Interventions: DRUG: brinzolamide 1% ophthalmic suspension|DRUG: Azopt 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Rapid Reinitiation of a Single Tablet Antiretroviral Therapy Using Symtuza® in HIV-1 Infected Treatment-Experienced Patients Off Therapy. (ReSTART)
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: DRUG: Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (FDC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Activating Messages for Enhancing Primary Care Practice (AMEP2): Effectiveness Study
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Public Service Announcement|BEHAVIORAL: Interactive Multi-Media Computer Program|BEHAVIORAL: Sleep Hygiene Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Prevention of Contrast Induced Nephropathy in Oncology Patients With Sodium Bicarbonate
Status: COMPLETED
Conditions: Radiographic Contrast Agent Nephropathy
Interventions: DRUG: sodium bicarbonate|DRUG: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pediatric Classical Hodgkin Lymphoma Consortium Study: cHOD17
Status: RECRUITING
Conditions: Hodgkin Lymphoma
Interventions: DRUG: bendamustine|DRUG: Etoposide|DRUG: Doxorubicin|DRUG: Bleomycin|DRUG: Vincristine|DRUG: Vinblastine|DRUG: Prednisone|DRUG: Filgrastim|DRUG: Brentuximab Vedotin|DRUG: Cyclophosphamide|DRUG: DTIC|OTHER: Quality of Life Measurements|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Mineral Density Changes of the Acetabulum After Revision Hip Arthroplasty Using Bone Impaction Grafting
Status: COMPLETED
Conditions: Disorder of Bone Density and Structure, Unspecified|Satisfaction
Interventions: RADIATION: DEXA: dual energy X-ray absorptiometry|OTHER: Short Form Health Survey 12|OTHER: VAS-satisfaction|OTHER: VAS-pain|OTHER: Harris Hip Score
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nivolumab and Dasatinib in Treating Patients With Relapsed or Refractory Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
Status: TERMINATED
Conditions: B Acute Lymphoblastic Leukemia With t(9;22)(q34;q11.2); BCR-ABL1|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Lymphoblastic Leukemia|Refractory Adult Acute Lymphoblastic Leukemia|Refractory Childhood Acute Lymphoblastic Leukemia
Interventions: DRUG: Dasatinib|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Bevacizumab With or Without Radiofrequency Ablation in Treating Unresectable Liver Metastases in Patients With Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: FOLFOX regimen|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin|PROCEDURE: conventional surgery|PROCEDURE: radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bupivacaine Versus Lidocaine Infiltration for Postoperative Pain in Thyroid Surgery
Status: RECRUITING
Conditions: Postoperative Pain|Thyroid Diseases|Anesthesia, Local
Interventions: DRUG: Bupivacaine 0.5% with 1:200 000 epinephrine|DRUG: Lidocaine 2% with 1:100 000 epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Discontinuation and Re-Treatment in Participants With Tenosynovial Giant Cell Tumor (TGCT) Previously Treated With Pexidartinib
Status: COMPLETED
Conditions: Tenosynovial Giant Cell Tumor
Interventions: DRUG: Pexidartinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: wXELIRI Versus FOLFIRI Regimen in the Treatment of Advanced Colorectal Cancer Patients
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: wXELIRI regimen|DRUG: FOLFIRI regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopy vs. Robotic Surgery for Endometriosis (LAROSE): a Prospective Randomized Controlled Trial
Status: COMPLETED
Conditions: Endometriosis
Interventions: PROCEDURE: Robotic surgery|PROCEDURE: Laparoscopic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Nutritional Geriatric Assessments in Identifying Malnutrition in Older Cancer Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Comprehensive Geriatric Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Histamine Pharmacodynamic Biomarker to Guide Treatment in Pediatric Asthma (HAS3)
Status: RECRUITING
Conditions: Allergic Asthma
Interventions: DRUG: Levocetirizine Dihydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Estrogen Treatment on Drug Metabolism and Transport
Status: RECRUITING
Conditions: Transgender Persons
Interventions: DRUG: Midazolam oral solution|DRUG: Digoxin Oral Tablet|DRUG: Acetaminophen Oral Tablet|DRUG: Midazolam Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study on the Intervention of Metabolic Syndrome Patients With Exercise Prescription Based on Ventilatory Threshold Using Cardiopulmonary Exercise Test
Status: COMPLETED
Conditions: Metabolic Syndrome X
Interventions: BEHAVIORAL: the maximum physiological value standardized group|BEHAVIORAL: the ventilatory threshold individualized group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PREcise Percutaneous Coronary Intervention for Stent OptimizatION in Treatment of COMPLEX Lesion (PRECISION-COMPLEX)
Status: RECRUITING
Conditions: Coronary Artery Disease|Angina Pectoris
Interventions: PROCEDURE: OCT-guided PCI|PROCEDURE: Angiography-guided PCI|DEVICE: Drug-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aromatase Inhibitors Plus Chemotherapy vs Chemotherapy as Neoadjuvant Treatment in Postmenopausal HR(+) Breast Cancer
Status: UNKNOWN
Conditions: Neoadjuvant Therapy
Interventions: DRUG: Letrozole (Aromatase Inhibitors)|DRUG: AC*4-T*4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of End-tidal Oxygen Monitoring During Preoxygenation Before Intubation for Acute Hypoxemic Respiratory Failure in ICU Setting
Status: NOT_YET_RECRUITING
Conditions: Acute Hypoxemic Respiratory Failure
Interventions: PROCEDURE: Protocol using end-tidal oxygen monitoring during preoxygenation before intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Influence of CPB Temperature on CABG Morbidity
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Myocardial Ischemia|Neurologic Manifestations
Interventions: PROCEDURE: cardiopulmonary bypass|PROCEDURE: heart arrest, induced
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Retrograde Autologous Blood Priming on Pulmonary Mechanics in Pediatric Cardiac Surgery
Status: COMPLETED
Conditions: Congenital Heart Disease
Interventions: PROCEDURE: Pediatric cardiac surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Natalizumab Versus Fingolimod in Relapsing-Remitting Multiple Sclerosis (RRMS) Participants
Status: TERMINATED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: natalizumab|DRUG: fingolimod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of 30 Units of TI (Technosphere® Insulin) Prepared With Insulin From Two Different Suppliers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TI-Inhalation Powder A|DRUG: TI-Inhalation Powder B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panitumumab Plus FOLFIRI in First-line Treatment of Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Panitumumab|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Search of a Paradoxical Fall in Maximum Expiratory Flow After Bronchodilation in Healthy Subjects
Status: UNKNOWN
Conditions: Paradoxical Fall in Maximum Expiratory Flows
Interventions: DRUG: Inhaled Bronchodilators +/- Inhaled Methacholine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ivabradine for Rate Control in Permanent Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Fibrillation, Persistent
Interventions: DRUG: Ivabradine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Measure Baricitinib (LY3009104) Absorption in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Baricitinib|DRUG: [^13C4D3^15N]-baricitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Functional Movement-power Training for Children With Developmental Coordination Disorder: A Randomised Controlled Trial
Status: UNKNOWN
Conditions: Developmental Coordination Disorder
Interventions: OTHER: PT-FMT|OTHER: FMT alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of 18F-Florastamin PET/CT Imaging in Patients With at Least Intermediate Risk Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: [18F]Florastamin Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of ImmunoPet Imaging of PD-L1 in Tumors Using 89Zr-DFO-REGN3504 in Adult Participants With Advanced PD-L1 Positive Malignancies
Status: TERMINATED
Conditions: Advanced PD-L1 Positive Malignancies
Interventions: DRUG: 89Zr˗DFO˗REGN3504
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Myeloid Leukemia in Remission|Aplastic Anemia|Chronic Myelomonocytic Leukemia|Hodgkin Lymphoma|Indolent Non-Hodgkin Lymphoma|Malignant Neoplasm|Myelodysplastic Syndrome|Myeloproliferative Neoplasm|Plasma Cell Myeloma|Refractory Anemia|Refractory Anemia With Excess Blasts|Refractory Anemia With Ring Sideroblasts|Refractory Cytopenia With Multilineage Dysplasia|Refractory Cytopenia With Multilineage Dysplasia and Ring Sideroblasts
Interventions: DRUG: Fludarabine|RADIATION: Total-Body Irradiation|BIOLOGICAL: T Cell-Depleted Donor Lymphocyte Infusion|DRUG: Cyclophosphamide|PROCEDURE: Peripheral Blood Stem Cell Transplantation|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Tacrolimus|DRUG: Mycophenolate mofetil|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT to Determine the Efficacy of Combining Hemospray With Medical Treatment in Acute Variceal Bleeding
Status: COMPLETED
Conditions: Variceal Hemorrhage
Interventions: DEVICE: Hemospray|DRUG: Octreotide|BIOLOGICAL: Blood transfusion|DRUG: Ceftriaxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dressing Wear Time After Breast Augmentation With Prosthesis
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: PROCEDURE: augmentation mammaplasty|PROCEDURE: augmentation mammaplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Platelet-Rich Plasma (PRP) Injection for the Treatment of Chronic Patellar Tendinopathy
Status: COMPLETED
Conditions: Chronic Patellar Tendinopathy|Chronic PT
Interventions: BIOLOGICAL: platelet rich plasma|OTHER: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing 17B Estradiol/TMG CC 1mg Vs. Tibolone In Postmenopausal Women
Status: COMPLETED
Conditions: Vasomotor Symptoms
Interventions: DRUG: 17B Estradiol (1mg) / (0.125 mg) TMG Continuous combined (Totelle)|DRUG: Tibolone (Livial)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of BMS-936558 (Nivolumab) Compared to Docetaxel in Previously Treated Advanced or Metastatic Squamous Cell Non-small Cell Lung Cancer (NSCLC) (CheckMate 017)
Status: COMPLETED
Conditions: Squamous Cell Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Nivolumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene Analysis and Treatment Optimization in Chinese Homozygous Familial Hypercholesterolemia
Status: COMPLETED
Conditions: Homozygous Familial Hypercholesterolemia
Interventions: GENETIC: Gene analysis|OTHER: Historical data of lipid-lowering drug administration|OTHER: Historical data of plasma lipids, xanthoma changes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison Between Home-made Vitrification & Thawing Media and a Commercially Available Brand on Blastocyst
Status: COMPLETED
Conditions: Blastocyst Disintegration
Interventions: BIOLOGICAL: home made vitrification & thawing kit|BIOLOGICAL: commercially made vitrification & thawing kit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Improving Hypertension Detection and Control Through a Hypertension Certification Program Based Upon the Hypertension Canada Guidelines
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Hypertension Canada Professional Certification Program: HC-PCP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Safety and Efficacy of de Novo Everolimus
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: DRUG: Everolimus Pill|DRUG: Sandimmun (Neoral) dose plus cellcept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study Assessing EndoPredict® Genomic Test Impact on Shared Decision of Adjuvant Chemotherapy in Patients With ER-positive, Her2-negative Early Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: EPClin genomic test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Topical 95% TCA in the Treatment of CIN 1 or Less After Low-grade Abnormality of Screening Test
Status: WITHDRAWN
Conditions: CIN1|Trichloroacetic Acid
Interventions: DRUG: Trichloroacetic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peanut Epicutaneous Phase II Immunotherapy Clinical Trial
Status: COMPLETED
Conditions: Peanut Hypersensitivity|Food Hypersensitivity|Hypersensitivity|Hypersensitivity, Immediate
Interventions: BIOLOGICAL: Placebo Viaskin® Patch|BIOLOGICAL: Low-dose DBV712 Viaskin® Patch|BIOLOGICAL: High-dose DBV712 Viaskin® Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preservative-Free Tafluprost (MK-2452) for the Treatment of Open-Angle Glaucoma or Ocular Hypertension (MK-2452-002)
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: Preservative-Free Tafluprost or vehicle|DRUG: Preservative-Free Timolol maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Surgical Treatment Approaches in Patients With Newly Diagnosed Lateral Epicondylitis: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Tennis Elbow
Interventions: OTHER: first physiotherapy|OTHER: second physiotherapy|OTHER: third physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Active Breaks on Mental Health and Classroom Climate in Chilean Schoolchildren Aged 6 to 10
Status: ENROLLING_BY_INVITATION
Conditions: Mental Health|School-age Children|School Health
Interventions: BEHAVIORAL: the Experimental Group, receiving a 12-week program of video-guided active breaks with curricular content in the school classroom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of S-1 Plus Oxaliplatin in First-line Treatment of Ederly Patients With Advanced Gastric Cancer
Status: UNKNOWN
Conditions: S-1 Plus Oxaliplatin
Interventions: DRUG: S-1,Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tofacitinib in Patients With Ulcerative Colitis in Stable Remission
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: CP-690,500 5 mg|DRUG: CP-690,550 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Efficacy, Safety, Tolerability & Pharmacokinetics of RO 205-2349 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: RO 205-2349
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study Evaluating Glofitamab in Combination With Venetoclax Plus Zanubrutinib or Venetoclax Alone in Subjects With Untreated or Relapsed/Refractory High-risk Mantle-cell Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Lymphoma, Mantle-Cell
Interventions: DRUG: Obinutuzumab|DRUG: Glofitamab|DRUG: Venetoclax Oral Product|DRUG: Zanubrutinib Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Betablocker or Aldosterone Antagonist Therapy on Patients With Liver Cirrhosis
Status: UNKNOWN
Conditions: Liver Cirrhosis|Portal Hypertension
Interventions: DRUG: propranolol|DRUG: spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scalable TELeheaLth Cancer CARe: The STELLAR Program to Treat Cancer Risk Behaviors
Status: NOT_YET_RECRUITING
Conditions: Obesity|Smoking Cessation|Physical Inactivity
Interventions: BEHAVIORAL: multiple behavior change therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abatacept Bone Effects in Psoriatic Arthritis With Bone Biomarker
Status: UNKNOWN
Conditions: Evaluate Bone Changes in Patients With PsA
Interventions: DRUG: Abatacept 125 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: DART: Diagnostic-CT-Enabled Planning: A Randomized Trial in Palliative Radiation Therapy
Status: UNKNOWN
Conditions: Advanced Cancer Requiring Palliative Radiation
Interventions: DIAGNOSTIC_TEST: Diagnostic-CT-enabled Planning|DIAGNOSTIC_TEST: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of Live Attenuated Varicella Vaccines in Healthy Adults, Adolescents and Children
Status: COMPLETED
Conditions: Varicella
Interventions: BIOLOGICAL: Investigational live attenuated varicella vaccine|BIOLOGICAL: control live attenuated varicella vaccine|BIOLOGICAL: diluent of lyophilized vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bathing Bundle Regimen in Reducing Gynecological Surgical Site Infection in Patients Undergoing Surgery
Status: COMPLETED
Conditions: Malignant Female Reproductive System Neoplasm
Interventions: PROCEDURE: Infection Prophylaxis and Management
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2 Multi-center Randomized Study to the Efficacy and Safety of AK105 Combined With Anrotinib Hydrochloride in Patients With Recurrent/Refractory Classical Hodgkin's Lymphoma
Status: ENROLLING_BY_INVITATION
Conditions: Recurrent/Refractory Classical Hodgkin's Lymphoma
Interventions: DRUG: AK105，Anrotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Novel Supplement on Sleep, Metabolism, Body Composition and Performance
Status: UNKNOWN
Conditions: Sleep Hygiene|Sleep Disturbance
Interventions: DIETARY_SUPPLEMENT: Melatonin and magnesium-containing pod|OTHER: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Repeated High-dose Inhaled Corticosteroids for Asthma
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: Placebo|DRUG: Fluticasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Training for the Remediation of Functional Brain Health in HIV
Status: COMPLETED
Conditions: HIV - Human Immunodeficiency Virus|Cognitive Impairment
Interventions: BEHAVIORAL: Plasticity-based Adaptive Cognitive Remediation (PACR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: First in Man Study of the DREAMS 2nd Generation Drug Eluting Absorbable Metal Scaffold (BIOSOLVE-II)
Status: UNKNOWN
Conditions: Coronary Artery Disease|Coronary Artery Stenosis
Interventions: DEVICE: Percutaneous Coronary Intervention (DREAMS) stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of INCB018424 Phosphate Cream in Subjects With Vitiligo
Status: COMPLETED
Conditions: Vitiligo
Interventions: DRUG: Ruxolitinib cream|DRUG: Vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Allergic Disease Onset Prevention Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis|Type 1 Hypersensitivity
Interventions: BIOLOGICAL: STMC-103H|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of DCVAC/PCa Added After Radical Primary Prostatectomy for Patients With Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Dendritic Cells DCVAC/PCa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Study Of The Safety Of Tanezumab In Arthritis Patients
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: BIOLOGICAL: Tanezumab|BIOLOGICAL: Tanezumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Using a Cuffed Endotracheal Tube on Limiting the Risk of Airway Fire
Status: COMPLETED
Conditions: Adenoidectomy|Tonsillectomy|Adenotonsillectomy
Interventions: OTHER: Cuffed ETT|OTHER: Uncuffed ETT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 2 Trial Using Talampanel in Patients With Recurrent High Grade Gliomas
Status: TERMINATED
Conditions: Glioblastoma Multiforme|Anaplastic Astrocytoma|Anaplastic Oligodendroglioma|Anaplastic Mixed Oligoastrocytoma
Interventions: DRUG: Talampanel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Anaesthesia With or Without Rocuronium in Intubation and Intraoperative Nerve-monitoring During Thyroid Surgery.
Status: COMPLETED
Conditions: Thyroid|Neuromuscular Blockade|Anesthesia Complication|Anesthesia Intubation Complication
Interventions: DRUG: Rocuronium 0.3 mg*kg|DRUG: No Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Improving Adherence in Adolescents and Young Adults With Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: BEHAVIORAL: Customized Adherence Enhancement for Adolescents and Young Adults (CAE-AYA)|BEHAVIORAL: Enhanced Treatment as Usual (ETAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Ceramic Water Filters to Reduce Cryptosporidium Infection in Kenya
Status: COMPLETED
Conditions: Cryptosporidium; Diarrhea|Cryptosporidiosis|Communicable Diseases|Diarrheal Disease
Interventions: OTHER: Ceramic water filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Power Over Pain (POP) Study
Status: COMPLETED
Conditions: Multiple Sclerosis|Spinal Cord Injury|Chronic Pain|Other and Unspecified Amputation Stump Complications|Muscular Dystrophies|Low Back Pain
Interventions: BEHAVIORAL: Pain Self-Management Intervention #1|BEHAVIORAL: Pain Self-Management Intervention #2|BEHAVIORAL: Pain Self-Management Intervention #3|BEHAVIORAL: Pain Self-Management Intervention #4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Performance of Universal Adhesive in Primary Molars: a Randomized Clinical Trial
Status: UNKNOWN
Conditions: Dental Caries
Interventions: OTHER: Self-etch approach|OTHER: Etch-and-rinse approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Supplementation With ω-3 Fatty Acids, Vitamin D and Calcium in Patients With Acute Lymphoblastic Leukemia.
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Vitamin d Deficiency
Interventions: DIETARY_SUPPLEMENT: ω-3 polyunsaturated fatty acids (DHA and EPA), Vitamin D (cholecalciferol), Calcium (calcium carbonate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of the Inhibition of the Mammalian Target of Rapamycin on Metabolism and Exercise
Status: TERMINATED
Conditions: Disorder Related to Renal Transplantation|Exercise, Aerobic|Muscle Strength
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Salivary Ap4A, SCCA, TROP2 in Oral Cancer Patients
Status: UNKNOWN
Conditions: Oral Cavity Squamous Cell Carcinoma|Saliva Altered|Precancerous Lesions
Interventions: OTHER: Saliva sampling|DIAGNOSTIC_TEST: ELISA|DIAGNOSTIC_TEST: HPLC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of the Interests of Mesure of Ultrasound " Angle of Progression " on the Cesarean Rate :a Randomized Comparative Prospective Study Multicenter Center Open
Status: COMPLETED
Conditions: Caesarean Rate
Interventions: PROCEDURE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy and Safety of Repetitive Transcranial Magnetic Stimulation for Upper-limb Motor Function Recovery in Subcortical and Brainstem Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke|Hemiplegia|Subcortical Infarction
Interventions: DEVICE: Low-frequency rTMS (experimental)|DEVICE: Low-frequency rTMS (sham comparator)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation Therapy for Task-Specific Dystonia
Status: COMPLETED
Conditions: Isolated Focal Hand Dystonia
Interventions: DEVICE: Repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Investigate Hepatic Impairment on PK, Safety, Tolerability of Camizestrant in Post-Menopausal Female Subjects
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Camizestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Duration of P-glycoprotein Inhibition After Oral Administration of HM30181AK Tablet
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HM30181AK 1mg|DRUG: HM30181AK 5mg|DRUG: HM30181AK 15mg|DRUG: HM30181AK 60mg|DRUG: Loperamide 2mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real-time fMRI Neurofeedback for Mild/Moderate Depression
Status: COMPLETED
Conditions: Depression Mild|Depression Moderate
Interventions: BEHAVIORAL: Real-time fMRI neurofeedback (rt-fMRI NFB)|BEHAVIORAL: Сognitive behavioral therapy (CBT)|BEHAVIORAL: EEG neurofeedback (EEG NFB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study Evaluating the Efficacy and Safety of ABSK021 (Pimicotinib)) in the Treatment of cGvHD Chronic Graft Versus Host Disease (cGvHD)
Status: ENROLLING_BY_INVITATION
Conditions: cGvHD
Interventions: DRUG: ABSK021
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Fluconazole and Ketoconazole in the Treatment of Fungal Infections of the Throat in Patients With Weakened Immune Systems
Status: COMPLETED
Conditions: Candidiasis, Esophageal|HIV Infections
Interventions: DRUG: Ketoconazole|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study Designed to Clinically Evaluate Sinus Wash Device Prototypes
Status: UNKNOWN
Conditions: Sinusitis|Maxillary Sinusitis
Interventions: DEVICE: SinuSafe Medical Device for Maxillary Sinus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Multiple Therapies in Cohorts of Participants With Locally Advanced, Unresectable, Stage III Non-Small Cell Lung Cancer (NSCLC)
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Alectinib|DRUG: Entrectinib|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptive Virtual Consultation Tool to Enhance Education and Understanding in Patients With Prostate Cancer
Status: RECRUITING
Conditions: Prostate Carcinoma
Interventions: BEHAVIORAL: Health Education|BEHAVIORAL: Health Education|OTHER: Informational Intervention|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH