pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Randomized Trial of Provider-Assisted Versus Patient-Initiated Enrollment in the Bedsider.Org Online Contraceptive Reminder Tool
Status: COMPLETED
Conditions: Contraceptive Adherence and Continuation
Interventions: OTHER: enrollment in online reminder system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Nuts and Olestra for Persistent Organic Pollutant Reduction (NO-POPs) Trial
Status: COMPLETED
Conditions: Persistent Organic Pollutants|Endocrine Disrupting Chemicals|Endocrine Disruptor Effects
Interventions: OTHER: Whole Nuts|OTHER: Olestra: Fat Free Pringles|OTHER: Vegetable Oil: Original Pringles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cold Knife Versus Monopolar Electrosurgery in Abdominal Incisions
Status: UNKNOWN
Conditions: Electrosurgery Versus Scalpel
Interventions: PROCEDURE: electrosurgery will be used for abdominal incision|PROCEDURE: scalpel will be used for abdominal incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 2, Open-Label, Multicenter Study of the GARFT Inhibitor in Patients With Metastatic Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Lung Neoplasms
Interventions: DRUG: AG2037
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Administration of Allogeneic-MSC in Patients With Non-Ischemic Dilated Cardiomyopathy
Status: RECRUITING
Conditions: Non-ischemic Dilated Cardiomyopathy
Interventions: BIOLOGICAL: allogeneic human mesenchymal stem cells (hMSCs)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC
Status: RECRUITING
Conditions: Metastatic Non-small Cell Lung Cancer
Interventions: DEVICE: NovoTTF-200T|DRUG: Pembrolizumab|DRUG: Platinum based chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Very-low Calorie Diet and Synbiotic Supplementation in Gut Microbiota (Pronokal Method)
Status: COMPLETED
Conditions: Weight Loss|Inflammation
Interventions: OTHER: Diet|DIETARY_SUPPLEMENT: Synbiotic1|DIETARY_SUPPLEMENT: Synbiotic2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Chemoradiotherapy Versus Esophagectomy After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophageal Cancer
Interventions: PROCEDURE: Esophagectomy|DRUG: 5-fluorouracil|DRUG: Cisplatin|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib in Treating Patients With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer in at Least the Second Remission
Status: TERMINATED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: sorafenib tosylate|OTHER: immunoenzyme technique|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cough in Reduced True Vocal Fold Mobility
Status: COMPLETED
Conditions: Unilateral Vocal Cord Paresis|Unilateral Vocal Cord Paralysis
Interventions: OTHER: cough airflow measure|OTHER: vocal tasks|OTHER: true vocal fold movement|OTHER: spirometry test|OTHER: maximum expiratory pressure (MEP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Clinical and Immunological Impact of Two Therapeutic Strategies in Chronic Inflammatory Diseases
Status: TERMINATED
Conditions: Inflammatory Bowel Diseases
Interventions: DRUG: Infliximab|DRUG: Mercaptopurine|DRUG: Azathioprine|DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing The Efficacy And Safety Of Avodart (Dutasteride) At Improving Urinary Symptoms In Men With Prostate Cancer Who Are Undergoing Seed Implantation
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: avodart|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Adverse Events, Change in Disease Activity, and How Oral ABBV-101 Moves Through the Body in Adult Participants With B-Cell Malignancies
Status: RECRUITING
Conditions: Hematologic Cancer
Interventions: DRUG: ABBV-101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Validation and Safety of the AC 12L ECG System Against a Standard of Care 12-Lead ECG (AC 12L ECG)
Status: RECRUITING
Conditions: Arrhythmia
Interventions: DEVICE: Kardia 12L
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Violence and Stress Assessment (ViStA) Project to Improve Post Traumatic Stress Disorder Management in Primary Care
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: OTHER: PCM|OTHER: MEU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Repair of Medial Patellofemoral Ligament Compared to Conservative Treatment for First Time Patella Dislocation
Status: TERMINATED
Conditions: Dislocated Patella|Torn Medial Patellofemoral Ligament
Interventions: PROCEDURE: Direct Medial Patellofemoral Ligament (MPFL) Repair|PROCEDURE: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Evaluating the Effects of First-line Oral cOmbination theraPy of maciTentan and tadalafIl in Patients With Newly Diagnosed pulMonary Arterial Hypertension (OPTIMA)
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: macitentan|DRUG: tadalafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Define the ECG Effects of Lixivaptan Compared to Placebo and Moxifloxacin in Healthy Adult Men and Women: A Thorough ECG Study
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: placebo|DRUG: lixivaptan|DRUG: moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Electroacupuncture Combined With Pregabalin in the Treatment of Trigeminal Herpetic Neuralgia: a Multicenter Randomized Controlled Trial Study Protocol
Status: RECRUITING
Conditions: Trigeminal Herpetic Neuralgia
Interventions: OTHER: Medication Group|OTHER: EA Group|OTHER: EA+Medication Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravaginal Electrical Stimulation With Different Treatment Frequency in Women With Idiopathic Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DEVICE: Intravaginal Electrical Stimulation (2 times/week)|DEVICE: Intravaginal Electrical Stimulation (5 times/week)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Frequency of Sleep Abnormalities in Patients With Irritable Bowel Syndrome and Effect of Pharmacological Intervention
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Melatonin 3 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Inhaled Epinephrine and Intramuscular Epinephrine Administered to Healthy Adults
Status: COMPLETED
Conditions: Anaphylactic Reaction
Interventions: DRUG: EpiPen ®.|DRUG: Epinephrine (0.3mg) inhaled|DRUG: Epinephrine (1.3mg)|DRUG: Epinephrine (4mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcome and OR Resource Use of Total Knee Arthroplasty Using Patient-Specific or Conventional Instrumentation
Status: COMPLETED
Conditions: Gonarthrosis
Interventions: PROCEDURE: PSI|PROCEDURE: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Biological Activity of Vesatolimod in HIV-1 Infected, Virologically Suppressed Adults
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Vesatolimod|DRUG: Placebo|DRUG: ARV regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ofatumumab Added to Dexamethasone in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: ofatumumab plus dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genito Urinary Function With High or Low Inferior Mesenteric Artery Ligation in Laparoscopic Anterior Rectal Resection
Status: COMPLETED
Conditions: Genito Urinary Function Evaluation
Interventions: PROCEDURE: During the surgical procedure of Laparoscopic Low Anterior Resection with Total mesorectal Excision .
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of SC0806 (Fibroblast Growth Factor 1 and a Device) in Traumatic Spinal Cord Injury Subjects
Status: UNKNOWN
Conditions: Spinal Cord Injury
Interventions: PROCEDURE: SC0806 and rehabilitation|OTHER: Rehabilitation only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buprenorphine in Acute Renal Colic Pain Management
Status: COMPLETED
Conditions: Acute Pain Management|Renal Colic
Interventions: DRUG: Buprenorphine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Advanced Non-Small Cell Lung Cancer Progressing After at Least One Prior Therapy For Metastatic Disease
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer|Lung Cancer|Metastatic Lung Cancer|NSCLC
Interventions: DRUG: nivolumab and ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Simvastatin and Irinotecan in Treating ES-SCLC Patients Relapsed From 1st Chemotherapy
Status: UNKNOWN
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Irinotecan|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ixabepilone in Asian Subjects With Unresectable or Metastatic Gastric Cancer
Status: COMPLETED
Conditions: Stomach Neoplasms
Interventions: DRUG: Ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Derived Mesenchymal Stem Cells Therapy in Systemic Lupus Erythematosus
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the ZoMaxx™ Drug-Eluting Stent System in Coronary Arteries
Status: COMPLETED
Conditions: Coronary Disease|Coronary Artery Disease|Coronary Restenosis
Interventions: DEVICE: ZoMaxx™ Drug-Eluting Coronary Stent System|DEVICE: TAXUS™ EXPRESS2™ Paclitaxel Eluting Coronary Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effects of Cholecalciferol Supplementation on Bone Health and Muscle Strength in Adults During Post-burn Period
Status: COMPLETED
Conditions: Vitamin D|Burn Injury
Interventions: DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oropharyngeal Immunoprophylaxis With High Polyphenolic Olive Oil as Clinical Spectrum Mitigating Factor in COVID-19.
Status: COMPLETED
Conditions: COVID-19
Interventions: DIETARY_SUPPLEMENT: High polyphenolic olive oil. (Early harvest olive oil).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Over-the-counter Dietary Supplements on Kidney Stone Risk
Status: COMPLETED
Conditions: Hyperoxaluria
Interventions: DIETARY_SUPPLEMENT: Aloe vera with cactus|DIETARY_SUPPLEMENT: Cranberry|DIETARY_SUPPLEMENT: Green tea extract|DIETARY_SUPPLEMENT: Bilberry|DIETARY_SUPPLEMENT: Cinnamon|DIETARY_SUPPLEMENT: Milk thistle|DIETARY_SUPPLEMENT: Turmeric|DIETARY_SUPPLEMENT: Aloe vera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tipifarnib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma
Interventions: DRUG: Tipifarnib|RADIATION: External Beam Radiation Therapy|DRUG: Temozolomide|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ⅰa Clinical Study Exploring Efficacy of SIBP-03 When Treating the Patients With Advanced Malignant Solid Tumors.
Status: COMPLETED
Conditions: Tumor
Interventions: BIOLOGICAL: SIBP-03
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amoxicillin and Metronidazole in Association With Non-surgical Therapy in Aggressive Periodontitis Treatment
Status: COMPLETED
Conditions: Generalized Aggressive Periodontitis
Interventions: DRUG: amoxicillin and metronidazole|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Intrathecal Morphine Combined With Low Dose Local Anesthetics on Postoperative Analgesia After Liver Resection
Status: COMPLETED
Conditions: Patients Receiving Hepatectomy Under General Anesthesia
Interventions: DRUG: Percutaneous injection|DRUG: Morphine|DRUG: Morphine+Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Electrical Pudendal Nerve Stimulation for Neurogenic Lower Urinary Tract Dysfunction
Status: COMPLETED
Conditions: Spinal Cord Injuries|Lower Urinary Tract Symptoms|Dysuria|Incontinence
Interventions: DEVICE: Electrical pudendal nerve stimulation|DEVICE: Transvaginal electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ganitumab and Gemcitabine Hydrochloride Followed by Radiation Therapy, Ganitumab, Capecitabine, and Maintenance Therapy in Treating Patients With Locally Advanced Cancer of the Pancreas
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: ganitumab|DRUG: capecitabine|DRUG: gemcitabine hydrochloride|RADIATION: 3-dimensional conformal radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Vonoprazan and Lansoprazole in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Vonoprazan|DRUG: Lansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose Escalation Trial of Tefinostat for Cancer Associated Inflamation in Hepatocellular Carcinoma (HCC)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Tefinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of Carcinogens Nicotine in Electronic Cigarettes Users
Status: UNKNOWN
Conditions: Smoking|Carcinogenesis of the Nicotine
Interventions: BIOLOGICAL: pregnancy test|BIOLOGICAL: urinary cotinine assesment|BIOLOGICAL: Urinary NNN assesement|BEHAVIORAL: Questionnaire (Fagerstrom test)|PROCEDURE: Measurement of carbon monoxide levels expired
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Nebulized Pulmicort Respules in Primary Lung Cancer Patients With COPD
Status: UNKNOWN
Conditions: Post Operative Complication, Pulmonary|Lung Cancer|COPD
Interventions: DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Acupuncture for Hot Flashes in Women Treated With Hormonal Therapy for Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: PROCEDURE: Acupuncture|PROCEDURE: Sham acupuncture therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Function in Idiopathic Thrombocytopenic Purpura (ITP) Patients With Eltrombopag
Status: COMPLETED
Conditions: Idiopathic Thrombocytopenic Purpura
Interventions: DRUG: eltrombopag|DRUG: corticosteroids (Aprednislon)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Golimumab in Early Axial Spondyloarthritis in Relation to Gut Inflammation
Status: COMPLETED
Conditions: Axial Spondyloarthritis
Interventions: DRUG: Golimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modalities of Surgical Treatment of Chiari Malformation Disease : Clinical Study and Outcomes
Status: RECRUITING
Conditions: Chiari Malformation, Type 1
Interventions: PROCEDURE: posterior fossa craniectomy with or without duraplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retrospective Foot and Ankle Data Collection
Status: UNKNOWN
Conditions: Lower Limb Surgery
Interventions: DEVICE: DARCO™ Headed Cannulated Screw|DEVICE: ORTHOLOC™ 3Di Recon-Midfoot/Flatfoot System|DEVICE: ORTHOLOCTM 3Di 2 Foot Reconstruction System: CROSSCHECK™ Module
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Risk Factor Involved in Knee Osteoarthritis (KOA)
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Influence of the metabolic syndrome (MetS) parameters on knee osteoarthritis (KOA) severity, the assesment of the reactive oxygen species and reactive nitrogen species in knee synovial fluid|OTHER: The influence of patellofemoral morphology in the radiological severity of knee osteoarthritis|OTHER: The influence of ROS from the synovial fluid on the severity of KOA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Ezetimibe on Platelet Aggregation and LDL Tendency to Peroxidation
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Simvastatin|DRUG: Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Eccentric Streching vs IASTM of Gastrocnemius and Soleus Muscles in Athletes With Ankle Sprain
Status: RECRUITING
Conditions: Ankle Sprains
Interventions: OTHER: eccentric streching|OTHER: IASTM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiox Liver Function Test Pivotal Trial
Status: WITHDRAWN
Conditions: Hepatic Failure|Liver Failure
Interventions: DRUG: 0.1 mg/kg ICG Dose|DRUG: 0.5 mg/kg ICG dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study in Multi-Coil Repetitive Transcranial Magnetic Stimulation (rTMS) for Treatment Resistant Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: Cervel Neurotech Deep Shaped-Field repetitive transcranial magnetic stimulator (DSF-rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adipose Derived Mesenchymal Cell Treatment in Lungtransplantation
Status: RECRUITING
Conditions: Lung Transplant Rejection
Interventions: DRUG: adipose derived mesenchymal stromal cells|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Therapeutic Confirmatory Study of Epaminurad Versus Febuxostat in Gout Patients
Status: RECRUITING
Conditions: Gout
Interventions: DRUG: Epaminurad 6 mg|DRUG: Epaminurad 9 mg|DRUG: Febuxostat 40 mg|DRUG: Febuxostat 80 mg|DRUG: Epaminurad 6 mg placebo|DRUG: Epaminurad 9 mg placebo|DRUG: Febuxostat 40 mg placebo|DRUG: Febuxostat 80 mg placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Patients With PNH
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: APL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EUROPT Clinical Trial to Study the Efficacy of One-Way Valve Implantation (New Treatment Algorithm) in Patients With Heterogeneous Emphysema
Status: UNKNOWN
Conditions: Emphysema|Chronic Obstructive Pulmonary Disease
Interventions: PROCEDURE: Bronchoscopic Lung Volume Reduction (BLVR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fludarabine, Cyclophosphamide, and Alemtuzumab in Patients With B-cell Chronic Lymphatic Leukemia (B-CLL)
Status: COMPLETED
Conditions: B-cell Chronic Lymphocytic Leukemia
Interventions: DRUG: FCCam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two Chemotherapy Regimens Compared With Observation in Treating Patients With Completely Resected Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: fluorouracil|DRUG: gemcitabine hydrochloride|DRUG: leucovorin calcium|OTHER: clinical observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of FP-1201-lyo (Interferon Beta-1a) in Prevention of Multi-Organ Failure on Patients After Open Surgery for a RAAA
Status: TERMINATED
Conditions: Preventive Medicine|Multi Organ Failure
Interventions: DRUG: Interferon Beta-1A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Open-label, Randomized, Multicenter Phase IIIb Study to Assess the Efficacy, Safety and Tolerance of BERIPLEX® P/N (Kcentra) Compared With Plasma for Rapid Reversal of Coagulopathy Induced by Vitamin K Antagonists in Subjects Requiring an Urgent Surgical Procedure
Status: COMPLETED
Conditions: Reversal of Coagulopathy
Interventions: BIOLOGICAL: Beriplex® P/N (Kcentra)|BIOLOGICAL: Fresh frozen plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Immune Checkpoint Inhibitor Combinations With Axitinib in Participants With Untreated Locally Advanced Unresectable or Metastatic Renal Cell Carcinoma
Status: RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Tobemstomig|DRUG: Tiragolumab|DRUG: Pembrolizumab|DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety and Tolerability, Pharmacokinetics, Food-effect and Pharmacodynamics of EHP-101 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: EHP-101 Liquid single dose|DRUG: EHP-101 Liquid multiple doses|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of SpineCare Used in Conjunction With Spinal Realignment Therapy
Status: COMPLETED
Conditions: Scoliosis Idiopathic
Interventions: DEVICE: SRT with SpineCare|DEVICE: SRT without SpineCare
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Efficacy and Safety of Empagliflozin in the Treatment of Pulmonary Arterial Hypertension
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: empagliflozin in treatment pulmonary aerterial hypertension|DRUG: placebo in treatment pulmonary aerterial hypertension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Trabectedin for the Treatment of Localized Myxoid / Round Cell Liposarcoma
Status: COMPLETED
Conditions: Liposarcoma,Myxoid
Interventions: DRUG: Trabectedin|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Internet-delivered Strengths Use Intervention
Status: COMPLETED
Conditions: Mental Health Wellness|Professional Burnout
Interventions: BEHAVIORAL: Internet-delivered strengths use intervention|BEHAVIORAL: Waiting-list
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: QLB After Nephrectomy
Status: COMPLETED
Conditions: Pain, Postoperative|Chronic Postoperative Pain
Interventions: PROCEDURE: QLB|DEVICE: PCA|PROCEDURE: GA|DRUG: Oxycodone|DRUG: Sevoflurane|DRUG: Fentanyl|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Combination Therapy With Intramuscular Avonex and Oral Cellcept in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Mycophenolate Mofetil (cellcept)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Transcranial Magnetic Stimulation in Subacute Stroke Patients With Severe Upper Limb Paresis
Status: RECRUITING
Conditions: Stroke Rehabilitation
Interventions: DEVICE: Repetitive transcranial magnetic stimulation|DEVICE: Sham Repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Physiotherapy in Patients With Temporomandibular Disorders.
Status: COMPLETED
Conditions: Temporomandibular Dysfunction (TMD)
Interventions: OTHER: Manual therapy|OTHER: Regular treatment control.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Сohort Study to Evaluate Exacerbations, Respiratory Symptoms, Physical Exercise Intolerance and Lung Functions Among Participants Who Use IQOS With Heatsticks Compared to Smokers of Conventional Cigarettes
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Respiratory Insufficiency|Physical Disability|Respiratory Disease
Interventions: OTHER: Heated Tobacco product IQOS/heatstick|OTHER: Smoking combustible cigarettes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exubera Large Simple Trial To Evaluate Long-Term Pulmonary And Cardiovascular Safety
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Randomization to Exubera (insulin human [rDNA origin] inhalation powder) or Usual Diabetes Care|DRUG: Randomization to Exubera (insulin human [rDNA origin] inhalation powder) or Usual Diabetes Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study for the Treatment of Dysfunctional Uterine Bleeding
Status: COMPLETED
Conditions: Metrorrhagia
Interventions: DRUG: Estradiol valerate/Dienogest (Natazia, Qlaira, BAY86-5027)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of AZR-MD-001 as Treatment for Meibomian Gland Dysfunction (MGD) or Contact Lens Discomfort (CLD)
Status: COMPLETED
Conditions: Meibomian Gland Dysfunction (MGD)|Contact Lens Discomfort (CLD)
Interventions: DRUG: AZR-MD-001 Vehicle|DRUG: AZR-MD-001 Active Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Environment Effect on Six-Minute Walk Test Performance
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease|Alpha-1 Antitrypsin Deficiency
Interventions: OTHER: six-minute walk study indoors|OTHER: six-minute walk study outdoors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pain Response Evaluation of a Combined Intervention to Cope Effectively
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain
Interventions: DRUG: duloxetine|BEHAVIORAL: Web-based Cognitive Behavioral Therapy (CBT)|OTHER: Nurse-delivered Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Nicotine Content Cigarettes in Vulnerable Populations: Opioid Use Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Tobacco Use Disorder
Interventions: OTHER: Cigarettes with varying nicotine content|OTHER: E-Cigarettes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: FLExAbility Sensor Enabled Substrate Targeted Ablation for the Reduction of VT Study
Status: COMPLETED
Conditions: Ventricular Tachycardia
Interventions: DEVICE: Market Approved RF Ablation System|DEVICE: FlexAbility SE Ablation Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of One-port and Two-port Tissue Expanders for Breast Reconstruction
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: Allergen one-port tissue expander placement|DEVICE: AlloX2 two-port tissue expander placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Almotriptan and Ubrogepant for the Acute Treatment of Migraine
Status: RECRUITING
Conditions: Migraine With Aura|Migraine Without Aura
Interventions: DRUG: Almotriptan 12.5 Mg Oral Tablet|DRUG: Ubrogepant 50Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Pulmonary Rehabilitation in Patients With Non-cystic Fibrosis Bronchiectasis
Status: COMPLETED
Conditions: Non-cystic Fibrosis Bronchiectasis
Interventions: BEHAVIORAL: Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of an Intervention for Improving Community-based Pediatric Attention-Deficit Hyperactivity Disorder (ADHD) Care
Status: COMPLETED
Conditions: ADHD
Interventions: OTHER: ADHD Collaborative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pilot Testing PICTURE-THIS
Status: RECRUITING
Conditions: Post-intensive Care Syndrome|Transitional Care|Critical Care|Health Services
Interventions: OTHER: PICTURE-THIS|OTHER: Enhanced Usual Care|BEHAVIORAL: Run-In Phase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Medico-economic Interest of the Patient Matched Cutting Blocks (Ancillary) MyKnee ® LBS During the Poses of Complete Prosthesis of Knee GMK ®. Multicentric, Prospective, Controlled, Opened, Randomised Study About a Medical Device. (My Knee)
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis
Interventions: DEVICE: the prosthesis GMK ® without the ancillary MyKnee ® LBS|DEVICE: Matched patient cutting blocks MyKnee ® LBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparing the Therapeutic Efficacy and Safety of DA-9701 With Domperidone in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease,Idiopathic
Interventions: DRUG: DA-9701|DRUG: Domperidone|DRUG: Placebo domperidone|DRUG: Placebo DA-9701
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Viscosupplementation in Patients With Hemophilic Arthropathy
Status: COMPLETED
Conditions: Osteoarthritis|Hemarthrosis|Hemophilia A|Hemophilia B
Interventions: PROCEDURE: Joint lavage and viscosupplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Tumor Ablation Effects by Irreversible Electroporation for Patients With Malignant Liver Tumors
Status: COMPLETED
Conditions: Malignant Liver Tumors
Interventions: PROCEDURE: irreversible electroporation|DEVICE: nanoknife AngioDynamics US Ltd
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Crossover Study to Assess the Relative Bioavailability and Bioequivalence of Niraparib Tablet Compared to Niraparib Capsule
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Niraparib Tablet|DRUG: Niraparib Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlled Human Malaria Infection (CHMI) After Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis
Status: COMPLETED
Conditions: Malaria|Plasmodium Falciparum
Interventions: BIOLOGICAL: PfSPZ Challenge|BIOLOGICAL: Normal Saline (NS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Carboplatin, Ixabepilone, and Cetuximab in Patients With Stage III or Stage IV Non-Small Cell Lung Cancer Previously Untreated With Chemotherapy
Status: WITHDRAWN
Conditions: Lung Cancer
Interventions: DRUG: cetuximab|DRUG: carboplatin|DRUG: ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Efficacy and Safety of JHL1101 Versus Rituximab in Patients With Previously Untreated Diffuse Large B-Cell Lymphoma (DLBCL)
Status: TERMINATED
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: BIOLOGICAL: JHL1101|BIOLOGICAL: MabThera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LCI-BRE-MTN-NIR-001:Ph I Study of Niraparib in Combo With Standard Chemo in Metastatic Trip Neg Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: Niraparib|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Paclitaxel|DRUG: Pegfilgrastim|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lutonix DCB Versus Standard Balloon Angioplasty for Treatment of Below-The-Knee (BTK) Arteries
Status: COMPLETED
Conditions: Critical Limb Ischemia
Interventions: DEVICE: Lutonix DCB|DEVICE: Uncoated PTA Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Delavirdine Used Together With Other Anti-HIV Drugs in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Delavirdine mesylate|DRUG: Lamivudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Bilateral DLPC tDCS in Drug-resistant Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DEVICE: Transcranial direct current stimulation (tDCS)|DRUG: anti-CGRP-mAbs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adapting Treatment to the Tumor Molecular Alterations for Patients With Advanced Solid Tumors: MyOwnSpecificTreatment
Status: RECRUITING
Conditions: Malignant Solid Neoplasms
Interventions: DRUG: Nilotinib (400 mg BID)|DRUG: Everolimus (10 mg QD)|DRUG: Sorafenib (400 mg BID)|DRUG: Lapatinib (1500 mg QD)|DRUG: Pazopanib (800 mg QD)|DRUG: Olaparib (300 mg BID)|COMBINATION_PRODUCT: Durvalumab + Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the High Frequency Digit Triplet Test in Cystic Fibrosis
Status: UNKNOWN
Conditions: Cystic Fibrosis|Sensorineural Hearing Loss
Interventions: OTHER: HFDT test|OTHER: Pure tone Audiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Comparing Post Cardiac Surgery Outcomes in ESRD Patient's With Early Dialysis Versus Standard Care
Status: WITHDRAWN
Conditions: Respiratory Failure|Shock|Coagulopathy
Interventions: PROCEDURE: Hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Reducing HIV Persistence in Lymph Nodes by Interleukin-15 (IL-15) Receptor Super-agonist (N-803) in Acute HIV Infection
Status: RECRUITING
Conditions: HIV/AIDS
Interventions: DRUG: N-803
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Lifestyle Physical Activity Intervention to Reduce Risk for Perinatal Cannabis Use - RCT
Status: RECRUITING
Conditions: Pregnancy
Interventions: BEHAVIORAL: LPA+Fitbit Intervention|BEHAVIORAL: Fitbit Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Changing Tactics? Optimizing ECT in Difficult-to-treat Depression
Status: RECRUITING
Conditions: Depression
Interventions: DEVICE: switch to BT electrode position|DEVICE: continue with RUL electrode position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Biodegradable Stents: Orsiro and BioMatrix
Status: COMPLETED
Conditions: All-comer|Percutaneous Coronary Intervention
Interventions: DEVICE: Drug-eluting biodegradable stent Orsiro implantation|DEVICE: Drug-eluting biodegradable stent BioMatrix or BioMatrix Flex implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Oscillation for Acute Respiratory Distress Syndrome (ARDS) Treated Early (OSCILLATE) Trial
Status: TERMINATED
Conditions: Acute Respiratory Distress Syndrome (ARDS)
Interventions: DEVICE: SensorMedics 3100B High Frequency Oscillatory Ventilator|PROCEDURE: Lung Protective Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Many Ways of Being Program
Status: RECRUITING
Conditions: Sexual Behavior|Unprotected Sex
Interventions: BEHAVIORAL: Many Ways of Being, an innovative sexual health promotion program focused on addressing rigid gender norms and promoting healthy relationships|BEHAVIORAL: A career readiness program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ultrasound of the Inferior Vena Cava in the Prevention of Hypotension After Induction of General Anesthesia
Status: NOT_YET_RECRUITING
Conditions: Elderly Patients Undergoing Elective Non-cardiac Surgery
Interventions: DIAGNOSTIC_TEST: Multidimensional ultrasound of the inferior vena cava
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacogenetics of Nicotine Addiction Treatment
Status: COMPLETED
Conditions: Nicotine Addiction
Interventions: DRUG: Varenicline|DRUG: Placebo|DRUG: Transdermal Nicotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cilostazol on Carotid Atherosclerosis Estimated by 3D Ultrasound in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Carotid Atherosclerosis
Interventions: DRUG: Cilostazol|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Dose Study of PRX003 in Subjects With Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: PRX003|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epratuzumab and Rituximab in Treating Patients With Previously Untreated Follicular Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: epratuzumab|BIOLOGICAL: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypoglycemia Associated Autonomic Failure in Type 1 Diabetes Mellitus
Status: WITHDRAWN
Conditions: Type 1 Diabetes
Interventions: DRUG: Fludrocortisone|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Empowering Patients to Better Manage Diabetes Through Self-Care
Status: COMPLETED
Conditions: Type I or Type II Diabetes (Excludes Gestational Diabetes)
Interventions: BEHAVIORAL: Pharmacist Counseling|BEHAVIORAL: Educational materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: First in Human Study of CDR404 in HLA-A*02:01 Participants With MAGE-A4 Expressing Solid Tumors
Status: RECRUITING
Conditions: Select Advanced Solid Tumors
Interventions: BIOLOGICAL: CDR404
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Early Treatment With Infliximab for Hip Arthritis Associated With Ankylosing Spondylitis (AS) (P06451)
Status: WITHDRAWN
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT