pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clinical Safety and Preliminary Efficacy of MUC1-DC-CTL Treatment in Stage IV Gastric Cancer.
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: BIOLOGICAL: MUC1-gene-DC-CTL|BIOLOGICAL: MUC1-peptide-DC-CTL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intestinal Microbiota in Prostate Cancer Patients as a Biomarker for Radiation-INduced Toxicity (IMPRINT)
Status: COMPLETED
Conditions: Prostate Cancer|Prostate Adenocarcinoma|Prostatic Neoplasms
Interventions: OTHER: Collection of human biofluids|OTHER: Patient reported outcome measures
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clavulanic Acid for the Treatment of Cocaine Use Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Cocaine Dependence
Interventions: DRUG: Clavulanic Acid Only Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tooth Discoloration Induced by Pulpotomy Materials
Status: ACTIVE_NOT_RECRUITING
Conditions: Tooth Discoloration
Interventions: PROCEDURE: Pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Attention Capacity and Before-school Physical Activity Intervention Program
Status: COMPLETED
Conditions: Physical Activity|Behavior|Child Behavior|Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Active-Start intervention|BEHAVIORAL: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Skipping Rope and Informational Pamphlet Among Adolescents in South Africa
Status: NOT_YET_RECRUITING
Conditions: Moderate-vigorous Physical Activity (MVPA)
Interventions: OTHER: Skipping rope and informational pamphlet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: European Trial on Enhanced DNA Repair Inhibition in Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma
Interventions: DRUG: Ganetespib|DRUG: Niraparib|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alemtuzumab in Myelodysplastic Syndrome (MDS), Aplastic Anemia, and T-Cell Large Granular Lymphocytic Leukemia (T-GL)
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Cord Stimulation for Respiratory Rehabilitation in Patients With Chronic Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries|Respiration Disorders
Interventions: DEVICE: Transcutaneous spinal cord stimulator|DEVICE: Respiratory Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The RECOVER IV Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: ST-segment Elevation Myocardial Infarction (STEMI)|Cardiogenic Shock
Interventions: DEVICE: Impella CP®|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: '4C' Intervention to Reduce SARS-CoV-2 (Covid-19) Transmission
Status: WITHDRAWN
Conditions: SARS-CoV Infection|Covid19
Interventions: BEHAVIORAL: Coaching, Cleaning, Communication, Collaboration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nutrition Therapy in Improving Immune System in Patients With Bladder Cancer That Can Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DIETARY_SUPPLEMENT: Nutritional Intervention|OTHER: Placebo Administration|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ObeSity and Jobs in SoCioeconomically Disadvantaged CommUnities: A Randomized CLinical Precision Public HealTh Intervention --The SCULPT-Job Study
Status: ENROLLING_BY_INVITATION
Conditions: Weight Maintenance|Weight Loss|Stress, Psychological|Job Stress|Diabetes Prevention|Obesity|Cardiovascular Risk Factor|Cardiovascular Diseases
Interventions: BEHAVIORAL: Diabetes Prevention Program + Job and Legal Services|BEHAVIORAL: Diabetes Prevention Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigation of Milk Peptides (Pep2Dia®) on Postprandial Blood Glucose Profile in Prediabetic Subjects
Status: COMPLETED
Conditions: Prediabetic State
Interventions: DIETARY_SUPPLEMENT: Pep2dia|DIETARY_SUPPLEMENT: maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of Meningococcal ACWY Conjugate Versus Polysaccharide Vaccine in Children 2 to 10 Years of Age
Status: COMPLETED
Conditions: Meningococcal Disease
Interventions: BIOLOGICAL: Meningococcal ACWY-CRM conjugate vaccine|BIOLOGICAL: Meningococcal ACWY-PS polysaccharide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Utility of Immature Granulocyte Count on the Prediction of Acute Appendicitis in the Suspected Acute Appendicitis
Status: COMPLETED
Conditions: Acute Appendicitis
Interventions: DIAGNOSTIC_TEST: Immature granulocyte count|DIAGNOSTIC_TEST: Immature granulocyte percentage
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Laryngeal Tube Ventilation on no Flow Time During Out of Hospital Cardiac Arrest
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: DEVICE: laryngeal tube ventilation and continuous chest compression|DEVICE: laryngeal tube ventilation and continuous chest compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Vagifem Low Dose for Postmenopausal Atrophic Vaginitis Symptoms
Status: COMPLETED
Conditions: Menopause|Postmenopausal Vaginal Atrophy
Interventions: DRUG: estradiol, 10 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Respiratory Protection Against the Effects of Wood Smoke Exposure in Young Healthy Adults (MASKON)
Status: ENROLLING_BY_INVITATION
Conditions: Healthy
Interventions: OTHER: NIOSH certified N95 personal face covering (mask)|OTHER: Surgical Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Identity Oriented Psychotrauma Therapy on Hashimoto in Adults
Status: COMPLETED
Conditions: Autoimmune Thyroiditis
Interventions: BEHAVIORAL: Identity Oriented Psychotrauma Therapy|DRUG: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetic Study Comparing Nicotine Delivery From E-cigarettes and a Conventional Cigarette in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: Use electronic cigarette or smoke conventional cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Re-Orchestration of Interregional Oscillatory Activity to Promote Visual Recovery
Status: ACTIVE_NOT_RECRUITING
Conditions: Visual Impairment|Stroke|Parkinson Disease
Interventions: OTHER: Cross-frequency dual-site tACS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Involvement of the Mediodorsal Nucleus of the Thalamus in Higher Order Cognitive Processes
Status: UNKNOWN
Conditions: Thalamic Infarction
Interventions: OTHER: neuroimaging|OTHER: Neuropsychological assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Standard Comprehensive Intervention to Treat First-episode Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: risperidone|DRUG: olanzapine|DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UNITY 2: A Study of an Investigational Treatment Regimen of DCV+ASV+BMS-791325 in a Fixed Dose Combination (the DCV 3DAA (Direct Acting Antiviral) Regimen) With or Without RBV for 12 Weeks for the Treatment of Chronic Hepatitis C Virus(HCV)Genotype 1 Infection in Subjects With Compensated Cirrhosis
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Daclatasvir|DRUG: Asunaprevir|DRUG: BMS-791325|DRUG: Ribavirin|DRUG: Placebo matching Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Volunteers of Single Doses of Orally Administered Investigational Product to Investigate Safety, Tolerability, and Pharmacokinecs.
Status: COMPLETED
Conditions: Dyslipidaemias
Interventions: DRUG: an undetermined dose of GSK1292263|DRUG: ascending dose of GSK1292263|DRUG: ascending dose of GSK1292263|DRUG: ascending dose of GSK1292263|DRUG: ascending dose of GSK1292263
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Lowering Weight in Severe Obesity by Embolization of the Gastric Artery Trial
Status: COMPLETED
Conditions: Obesity, Morbid
Interventions: DEVICE: Endobar Infusion Catheter System|BEHAVIORAL: Behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple-Dose Pharmacokinetics (PK), and Pharmacodynamic (PD) Effect of NSI-189 Phosphate in Depression Patient Subjects
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: NSI-189 Phosphate|DRUG: microcrystalline cellulose capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of SC Formulation and Japanese Ethnobridging Study for PRA023
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PRA023 IV Low Dose|DRUG: PRA023 SC|DRUG: Placebo IV|DRUG: Placebo SC|DRUG: PRA023 IV High Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Immunogenicity Study of Ad26-ENVA and Ad35-ENV HIV Vaccines in Healthy HIV-uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Ad35-ENV vaccine|BIOLOGICAL: Ad26.ENVA.01 vaccine|BIOLOGICAL: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Mechanical Versus Manual Traction in the Management of Low Back Pain.
Status: COMPLETED
Conditions: Low Back Pain|Low Back Pain, Mechanical|Disc Degeneration|Disc Prolapse|Disc Prolapse With Radiculopathy|Lumbar Radiculopathy
Interventions: PROCEDURE: Hot Pack|PROCEDURE: Manual Traction|PROCEDURE: Mechanical Traction|PROCEDURE: Joint Mobilization|PROCEDURE: TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Usability Assessment of Naloxone by Community Members
Status: COMPLETED
Conditions: Drug Overdose
Interventions: DEVICE: Syringe and needle|DEVICE: Intranasal mucosal atomization device|DEVICE: Nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Precision Therapy for Solid Tumors: Synergistic CDK4/6 Inhibition and Anti-VEGF Targeting LncRNA
Status: RECRUITING
Conditions: Cancer|Solid Tumor|Colorectal Cancer|Breast Cancer|Ovarian Cancer|Lung Cancer|Targeted Therapy|Chemotherapy|Immunotherapy|Precision Therapy
Interventions: GENETIC: SNP|DRUG: Palbociclib 125mg|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Multilevel Intervention to Improve Timely Cancer Detection and Treatment Initiation
Status: RECRUITING
Conditions: Neoplasms|Hiv|Cervical Cancer|Breast Cancer|HNSCC|Vulvar Cancer|Anal Cancer|Cancer Suspect
Interventions: OTHER: Potlako intervention|OTHER: Enhanced care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Immunogenicity of GSK Biologicals' Herpes Zoster Vaccine 1437173A in Healthy Ethnic Japanese Adults
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Herpes Zoster Vaccine GSK 1437173A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 1 Novel Live Attenuated Serotype 2 Oral Polio Vaccine Study in Inactivated Polio Vaccine (IPV) Primed Adults
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: Novel OPV2 candidate 1|BIOLOGICAL: Novel OPV2 candidate 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Performance of Princess® VOLUME for the Treatment of Facial Lipoatrophy, Asymmetry or Scars
Status: COMPLETED
Conditions: Facial Lipoatrophy|Morphological Asymmetry of the Face|Debilitating Scars
Interventions: DEVICE: Princess® VOLUME
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate Efficacy of EB-PA as Protein Amplifier for Skeletal Muscle Strength & Growth
Status: RECRUITING
Conditions: Skeletal Muscle Strength & Growth
Interventions: DIETARY_SUPPLEMENT: Resistance Training + Placebo (Capsule) + Placebo (Sachet)|DIETARY_SUPPLEMENT: Resistance Training + Whey protein (40 gms) + Placebo (Capsule)|DIETARY_SUPPLEMENT: Resistance Training + Whey protein (40 gms) + EB-PA (500 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Ph. 1, Evaluation of Safety, Tolerability, PK, Anti-tumor Activity of STP707 IV in Subjects With Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: STP707
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Anthrax Vaccines Px563L and RPA563 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Anthrax
Interventions: BIOLOGICAL: Px563L, RPA563, or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: FS-1 Drug for Treatment of Multiple Drug-resistant Tuberculosis
Status: COMPLETED
Conditions: Tuberculosis, MDR
Interventions: DRUG: FS-1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vonoprazan for Helicobacter Pylori Eradication in Adolescents
Status: COMPLETED
Conditions: Treatment Effectiveness
Interventions: DRUG: Vonoprazan|DRUG: Amoxicillin|DRUG: Clarithromycin|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Real-time fMRI Neurofeedback Training on the Anterior Insula Based on Interoceptive Processing
Status: COMPLETED
Conditions: Healthy
Interventions: PROCEDURE: real-time fMRI neurofeedback training procedure|PROCEDURE: real-time fMRI sham-controlled neurofeedback training procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 2 Study of AFM13 in Combination With AB-101 in Subjects With R/R HL and CD30+ PTCL
Status: RECRUITING
Conditions: Relapsed or Refractory Hodgkin Lymphoma|Peripheral T Cell Lymphoma
Interventions: DRUG: AFM13|DRUG: AB-101|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Three Distinct Exercise Types on Fatigue, Anxiety, and Depression in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Spinning Class|BEHAVIORAL: Yoga Class|BEHAVIORAL: Dance Class
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of SAR113945 in Japanese Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: placebo|DRUG: SAR113945
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of the Type and Route of Nutritional Support on Infectious Complications After Upper Gastrointestinal Surgery
Status: COMPLETED
Conditions: Gastrointestinal Surgery
Interventions: DRUG: Reconvan, Dipeptiven, Omegaven
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Education for Recognition and Management of Delirium
Status: COMPLETED
Conditions: Delirium|Intensive Care Unit Syndrome|Nurse-Patient Relations
Interventions: BEHAVIORAL: OSCEs|BEHAVIORAL: Lecture|BEHAVIORAL: E-learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Trial Assessing the Immunologic Response to a Influenza Vaccine Delivered Using an Jet Injection Device or a Needle Syringe
Status: COMPLETED
Conditions: Influenza Prophylaxis
Interventions: DEVICE: Stratis Jet Injector|DEVICE: Needle and Syringe|BIOLOGICAL: 2011-2012 Fluzone trivalent inactivated influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exploring Renal Transplants Using Hepatitis C Infected Donors for HCV-negative Recipients
Status: COMPLETED
Conditions: End-Stage Renal Disease|Hepatitis C
Interventions: DRUG: Zepatier|DRUG: Ribavirin|DRUG: Sofosbuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting the Gut Dysbiosis to Treat Inflammation-driven Synaptopathy in MS
Status: RECRUITING
Conditions: Patient Participation
Interventions: DIETARY_SUPPLEMENT: Prebiotics and Probiotics supplementation|DIETARY_SUPPLEMENT: Placebo supplementation|PROCEDURE: peripheral blood withdrawal|PROCEDURE: Transcranial Magnetic Stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Strategies in Maintenance for Patients Receiving Long-term Therapy (S.I.M.P.L.E.) With MMX (Multi-Matrix System) Mesalamine for Ulcerative Colitis (UC)
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: MMX Mesalamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DOR/ISL in HIV-1 Antiretroviral Treatment-naïve Participants (MK-8591A-053)
Status: RECRUITING
Conditions: HIV-1 Infection
Interventions: DRUG: DOR/ISL|DRUG: BIC/FTC/TAF|DRUG: Placebo to DOR/ISL|DRUG: Placebo to BIC/FTC/TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Real-Time Near-infrared (NIR) Mapping of Sentinel Lymph Nodes in Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: NIR Imaging with FLARE and Mini-FLARE Imaging System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Home-Based SolUtion for Remote Atrial Fibrillation Screening to PrevenT RecUrrence StrOke (HUA-TUO AF Trial)
Status: NOT_YET_RECRUITING
Conditions: Stroke, Cardiovascular
Interventions: DEVICE: Remote atrial fibrillation screening with handheld single lead ECG recorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Effects of Intranasal Oxytocin on Cigarette Smoking
Status: COMPLETED
Conditions: Nicotine Dependence|Tobacco Smoking
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cholecalciferol and Calcifediol Are Both Useful to Improve Vitamin D Serum Levels
Status: RECRUITING
Conditions: Hypovitaminosis D
Interventions: DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Face-to-face Intubation in Morbidly Obese
Status: COMPLETED
Conditions: Intubation;Difficult|Obesity, Morbid
Interventions: DEVICE: AirTraq videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Maggot Debridement Therapy Versus Conventional Dressing Therapy to Treat Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot Ulcers
Interventions: PROCEDURE: Maggot debridement therapy|PROCEDURE: Conventional Dressing Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Switching Calcineurin Inhibitor to Everolimus After Kidney Transplantation in Adults
Status: UNKNOWN
Conditions: Kidney Transplant|Immunosuppression
Interventions: DRUG: Everolimus|DRUG: calcineurin inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 4D-125 in Patients With X-Linked Retinitis Pigmentosa (XLRP)
Status: ACTIVE_NOT_RECRUITING
Conditions: X-Linked Retinitis Pigmentosa
Interventions: BIOLOGICAL: 4D-125 IVT Injection|OTHER: Observational
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Three Different Postcesarean Analgesic Techniques on QbsQor-10 Score: Prospective, Randomized Trial
Status: RECRUITING
Conditions: Postoperative Recovery
Interventions: PROCEDURE: Intraperitoneal local anasthetic application + local anesthetic wound infiltration|PROCEDURE: Intrathecal morphine application|PROCEDURE: Quadratus lumborum block tip 1 application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MK0462 in Treatment of Migraine With Recurrence (MK0462-022)
Status: COMPLETED
Conditions: Migraine Headache
Interventions: DRUG: rizatriptan benzoate (MK0462)|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted High-definition Transcranial Direct Current Stimulation (HD-tDCS) for Reducing Post-stroke Movement Impairments
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Transcranial direct current stimulation (high-definition)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Aspirin in Preventing Recurrence of Cancer in Patients With HER2 Negative Stage II-III Breast Cancer After Chemotherapy, Surgery, and/or Radiation Therapy
Status: TERMINATED
Conditions: Node Positive HER2 Negative Breast Cancer
Interventions: OTHER: Placebo|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Eluting Stenting and Aggressive Medical Treatment for Preventing Recurrent Stroke in Intracranial Atherosclerotic Disease Trial
Status: RECRUITING
Conditions: Intracranial Atherosclerotic Disease|Stroke
Interventions: DEVICE: Drug Eluting Stent implantation|DRUG: Aggressive medical treatment|BEHAVIORAL: Risk factor management|DRUG: Standard medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of 3D Movie Viewing on Stereopsis in Strabismus and / or Anisometropic Amblyops
Status: COMPLETED
Conditions: Amblyopia|Anisometropic Amblyopia|Strabismic Amblyopia
Interventions: OTHER: 3D movie viewing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serratus Plane Block vs Erector Spinae Plane Block on Postoperative Analgesia in Patients Undergoing Unilateral Breast Surgery
Status: COMPLETED
Conditions: Breast Cancer|Postoperative Pain
Interventions: DRUG: Bupivacaine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Distraction for Maternal Milk Expression (PILOT)
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Milk Expression, Breast|Breast Milk Collection
Interventions: DEVICE: Virtual Reality Distraction|OTHER: Standard Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Efficacy of Fractionated Carbon Dioxide Therapy in Postoperative Lower Extremity Wound Healing
Status: COMPLETED
Conditions: Leg Ulcer
Interventions: DEVICE: CO2RE® (Syneron Candela Corp, Wayland, MA)|OTHER: Sham laser treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Intubation Conditions During Rapid Sequence Induction Obtained With Modified Time Principal Induction With a Standard Intubation Dose of Rocuronium Versus Succinylcholine
Status: RECRUITING
Conditions: Anesthesia
Interventions: DRUG: Modified Time Principle Induction (MTPI) with rocuronium|DRUG: RSI succinylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Latency Antibiotics in Previable PPROM, 18 0/7- 22 6/7 WGA
Status: RECRUITING
Conditions: Rupture of Membranes; Delayed Delivery (Following Spontaneous Rupture)|Rupture of Membranes; Premature|Rupture of Membranes; Premature, Affecting Fetus|Preterm Birth|Preterm PROM (Pregnancy)|Preterm Labor
Interventions: DRUG: Antibiotics, oral Azithromycin and oral Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carvedilol vs Band Ligation vs Combination Therapy for Primary Prophylaxis of Variceal Bleeding
Status: WITHDRAWN
Conditions: Portal Hypertension Related to Cirrhosis
Interventions: DRUG: Carvedilol|PROCEDURE: Variceal band ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Remineralizing Effect of Aloe Vera Versus Diode Laser for Management of Deep Carious Lesions.
Status: COMPLETED
Conditions: Deep Caries
Interventions: OTHER: no intervention|DEVICE: diode laser|DIETARY_SUPPLEMENT: Aloe Vera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parasitic Ulcer Treatment Trial
Status: RECRUITING
Conditions: Acanthamoeba Keratitis
Interventions: DRUG: Polyhexamethylene biguanide (PHMB)|DRUG: Topical corticosteroid|OTHER: Topical placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Motivational Intervention (BMI) on the Deprescription of Benzodiazepines and Related Substances in Adult Chronic Drug Users
Status: NOT_YET_RECRUITING
Conditions: Benzodiazepine Withdrawal
Interventions: OTHER: Brief motivational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dose Dense Doxorubucin and Cyclophosphamide Followed by Eribulin Mesylate for the Adjuvant Treatment of Early Stage Breast Cancer
Status: COMPLETED
Conditions: HER2-normal
Interventions: DRUG: eribulin mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety of Nemolizumab in Subjects With Moderate-to-Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Moderate-to-Severe Atopic Dermatitis
Interventions: DRUG: Placebo|DRUG: Nemolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Effect With Hyaluronate Injection on Risk of Fall in Geriatric Women With Knee Osteoarthritis
Status: RECRUITING
Conditions: Osteo Arthritis Knee
Interventions: DEVICE: Therapeutic Ultrasonic|DRUG: Hyaluronan intra-articular injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Active Vitamin D Effect on Left Ventricular Hypertrophy
Status: TERMINATED
Conditions: Chronic Kidney Disease|Secondary Hyperparathyroidism|Left Ventricular Hypertrophy
Interventions: DRUG: Alfacalcidiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Faecal Microbiota Transplantation in Cirrhosis
Status: COMPLETED
Conditions: Cirrhosis of the Liver
Interventions: BIOLOGICAL: Faecal microbiota transplantation|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Multicenter, Double-blind, Randomized, Parallel-group, Phase III Study of the Efficacy and Safety of QL1701 Plus Docetaxel Versus Herceptin® Plus Docetaxel as First Line Therapy in Patients With HER2-positive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: QL1701|DRUG: Herceptin®|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of the Drug DPC 083 in Combination With Nucleoside Analogue Reverse Transcriptase Inhibitors in HIV-1-Infected Patients Who Are Failing Treatment With Nonnucleoside Reverse Transcriptase Inhibitors
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: DPC 083
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Corticosteroid/Ropivacaine Versus Corticosteroid/Saline Injections for Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Ropivacaine|DRUG: Normal saline|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Pharmacokinetics of VRC07-523LS in the Sera and Mucosae of Healthy, HIV-Uninfected Adult Participants
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: VRC07-523LS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of the Relevance of a Medico-social Care of Elderly Patients, in Relay Between Hospital and Home: Experimentation of TEMPORARY HERBERGEMENT in Retirement Home " EHPAD " in Seine-et-Marne Department
Status: TERMINATED
Conditions: Patients Beneficiting of Temporary Hebergement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Feasibility and Safety of Laryngoscopic Microsurgery Under Non-intubation Anesthesia
Status: COMPLETED
Conditions: Spontaneous Breathing|Laryngomicrosurgery|Superior Laryngeal Nerve Block
Interventions: PROCEDURE: Non-intubated Laryngomicrosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Lung Ultrasonography on the Prognosis and Postoperative Outcomes in Cardiac Surgical Patients
Status: NOT_YET_RECRUITING
Conditions: Ischemic Heart Disease|Aortic Stenosis, Severe|Aortic Insufficiency|Mitral Stenosis|Mitral Insufficiency|Mitral Stenosis With Insufficiency|Tricuspid Insufficiency|Ascending Aortic Aneurysm
Interventions: DIAGNOSTIC_TEST: Ultrasound examination of the lungs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ability to Maintain or Achieve Clinical and Endoscopic Remission With MMX Mesalamine Once Daily in Adults With Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: MMX mesalamine/ mesalazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Oxytocin for the Treatment of Social Impairment in Individuals With High Functioning Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Pervasive Developmental Disorder|ASD|PDD
Interventions: DRUG: Intranasal Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is it Really Necessary to Insert a Nephrostomy Tube or Double J Stent in Percutaneous Nephrolithotomy?
Status: RECRUITING
Conditions: Kidney Calculi|Postoperative Pain
Interventions: DEVICE: nephrostomy tube|DEVICE: double J stent|PROCEDURE: totally tubless
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety, Pharmacokinetics and Pharmacodynamics of BBT-877 in Healthy Japanese Male
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BBT-877 single dose|DRUG: Placebo single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of Peginterferon Alfa-2a in Combination With Ribavirin in Participants With Chronic Hepatitis C and Compensated Liver Cirrhosis
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Peginterferon alfa-2a|DRUG: Ribavirin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Catheter Tip Location Relative to the Femoral Nerve on Sensory and Motor Function
Status: COMPLETED
Conditions: Continuous Femoral Nerve Blocks in Healthy Volunteers
Interventions: PROCEDURE: Catheter Anterior to the Femoral Nerve|PROCEDURE: Catheter Posterior to the Femoral Nerve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Global Prospective Case Series Using a Single-Use Duodenoscope
Status: COMPLETED
Conditions: Endoscopic Retrograde Cholangiopancreatography
Interventions: DEVICE: Exalt Model D Single-Use Duodenoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Adapting an Advocacy Services Intervention for Latinx Families of Transition-aged Youth With Autism Spectrum Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism
Interventions: BEHAVIORAL: ASISTIR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combined Steroid and Cyclosporin as First-line Treatment in Adults With Primary Immune Thrombocytopenia
Status: NOT_YET_RECRUITING
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Cyclosporine Oral Product|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primordial Dwarfism Registry
Status: RECRUITING
Conditions: MOPDII|RNU4atac-opathy (e.g. MOPDI/III, Lowry-Wood Syndrome, Roifman Syndrome)|Meier-Gorlin Syndrome|Saul-Wilson Syndrome|Ligase 4 Syndrome|Microcephalic Primordial Dwarfism
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ORION: Effects of Cenicriviroc on Insulin Sensitivity in Subjects With Prediabetes or Type 2 Diabetes Mellitus (T2DM) and Suspected NAFLD
Status: COMPLETED
Conditions: Prediabetic State|Non-alcoholic Fatty Liver Disease|Type 2 Diabetes Mellitus
Interventions: DRUG: Cenicriviroc 150 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SPYRAL PIVOTAL - SPYRAL HTN-OFF MED Study
Status: COMPLETED
Conditions: Hypertension|Vascular Diseases|Cardiovascular Diseases
Interventions: DEVICE: Symplicity Spyral™ multi-electrode renal denervation system|PROCEDURE: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Glucodynamic Crossover Study of Subcutaneously (SC) Administered Insulin Lispro + Recombinant Human Hyaluronidase (rHuPH20) and Regular Human Insulin + rHuPH20 Compared to Insulin Lispro Alone
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Insulin Lispro|DRUG: Regular Human Insulin|DRUG: rHuPH20
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Study to Predict the Benefits of First-line Humidification Use and Comparison of the Effect of ThermoSmart™ and no Humidification on Adherence
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Heated humidification (ThermoSmart)|DEVICE: No Humidification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adding Ezetimibe Tablet to Ongoing Treatment With Atorvastatin in Subjects With High Cholesterol and Multiple Coronary Heart Disease Risk Factors (Study P04060)(COMPLETED)
Status: COMPLETED
Conditions: Hypercholesterolemia|Coronary Arteriosclerosis
Interventions: DRUG: Ezetimibe|DRUG: Placebo|DRUG: Atorvastatin 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of a Predictive Risk Equation for Type 2 Diabetes in Families With Risk
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: OTHER: HbA1c measurement|OTHER: Oral Glucoce Tolerance Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigation of the Efficacy of Rocabado Exercises in Individuals With Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Neck Stabilization Exercise|OTHER: Neck Stabilization Exercise + Rocabado Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Accelerated Theta Burst Stimulation for Inpatients With Bipolar Disorder
Status: TERMINATED
Conditions: Bipolar Disorder, Manic|Bipolar Disorder I
Interventions: DEVICE: Accelerated intermittent theta-burst stimulation over right DLPFC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of a Sublingual Immunotherapy Solution to Treat Patients Suffering From Birch Pollen Allergic Rhinoconjunctivitis
Status: COMPLETED
Conditions: Hypersensitivity|Allergic Rhinitis|Allergic Conjunctivitis|Seasonal Allergy
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: Birch pollen allergen extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Lumbar Spinal Stenosis; Comparison of Two Different Surgical Methods; Mini-invasive Decompression to X-stop
Status: TERMINATED
Conditions: Lumbar Spinal Stenosis|Radiculopathy
Interventions: PROCEDURE: Minimal invasive decompression|PROCEDURE: Interspinous Process Decompression (IPD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Topographic Mapping of Medial Antebrachial Cutaneous Nerve
Status: COMPLETED
Conditions: Nerve Block|Surgery|Anesthesia|Brachial Plexus Block
Interventions: PROCEDURE: axillary block|DRUG: Scandicaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Topiramate vs Metformin on Cardio-Metabolic Profile in Schizophrenia on Atypical Antipsychotics
Status: COMPLETED
Conditions: Metabolic Syndrome|Schizophrenia
Interventions: DRUG: Metformin|DRUG: Topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet-delivered Cognitive Behavior Therapy for Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Arrhythmia
Interventions: BEHAVIORAL: Internet-delivered cognitive behavior therapy|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Efficacy and Safety of Fingolimod (FTY720) in Patients With Relapsing-remitting Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Fingolimod 0.5 mg|DRUG: Fingolimod 1.25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Appetite Regulation by a Breakfast Soft Bread
Status: COMPLETED
Conditions: The Focus of the Study is Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Puravita Breakfast|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Open-Label Study to Assess Lacosamide Safety as Add-on Therapy for Primary Generalized Tonic-Clonic Seizures in Subjects With Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Lacosamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma
Status: RECRUITING
Conditions: Advanced Cholangiocarcinoma|Metastatic Cholangiocarcinoma|Refractory Cholangiocarcinoma|Stage III Hilar Cholangiocarcinoma AJCC v8|Stage III Intrahepatic Cholangiocarcinoma AJCC v8|Stage IV Hilar Cholangiocarcinoma AJCC v8|Stage IV Intrahepatic Cholangiocarcinoma AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|BIOLOGICAL: Heat Shock Factor 1 Pathway Inhibitor NXP800|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|PROCEDURE: Ultrasound-Guided Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT