pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of IPV Assessed With Functional Imaging
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: intrapulmonary percussive ventilation|OTHER: standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endodontic Microsurgery With the Use of L-PRF and an Occlusive Membrane: a Randomized Controlled Clinical Trial
Status: COMPLETED
Conditions: Periapical Periodontitis
Interventions: PROCEDURE: EMS|DEVICE: + occlusive membrane|DEVICE: conebeam CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single-centre Study of Everolimus as GvHD Prophylaxis After Post-Transplantation Cyclophosphamide After Allogeneic SCT
Status: COMPLETED
Conditions: Graft-versus-Host Disease
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: MEdication Counselling Models for Outpatient oRal antIcoaguLation
Status: NOT_YET_RECRUITING
Conditions: Anticoagulants; Circulating, Hemorrhagic Disorder
Interventions: OTHER: Telepharmacy-led counselling|OTHER: Pharmacist-led counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Clinical Study to Assess the Safety, Tolerability and Pharmacokinetics of Oral SRT2104 Capsules Administered to Healthy Elderly Subjects for 28 Days
Status: COMPLETED
Conditions: Atrophy, Muscular
Interventions: DRUG: Placebo|DRUG: SRT2104
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Denileukin Diftitox in Treating Patients With Fludarabine-Refractory B-Cell Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: denileukin diftitox
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Role of Neuroinflammation in Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain|Back Pain With Radiation|Back Pain Without Radiation|Back Pain Lower Back Chronic|Back Ache|Pain, Chronic
Interventions: DRUG: Minocycline Hydrochloride 100mg Capsule|DIAGNOSTIC_TEST: Magnetic Resonance-Positron Emission Tomography Imaging|OTHER: Placebo Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics of TB001 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TB001|DRUG: TB001|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt, Following Corneal Transplant Surgery
Status: COMPLETED
Conditions: Corneal Edema|Corneal Defect|Corneal Transplant|Penetrating KeratoPlasty|Anterior Chamber Inflammation|Ocular Pain|Intraocular Pressure
Interventions: DRUG: Dextenza 0.4Mg Ophthalmic Insert|DRUG: Prednisolone Acetate 1% Oph Susp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Synbiotics Supplementation on the Uremic Toxin Indoxyl Sulfate Level and Constipation in End-stage Renal Disease Patients Undergoing Hemodialysis
Status: UNKNOWN
Conditions: Constipation|End Stage Renal Disease on Dialysis
Interventions: DIETARY_SUPPLEMENT: Synbiotics containing Lactobacillus acidophilus & Bifidobacterium longum 5x10^9 CFU and FOS 60 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of PNF and Lumbar Stabilization Exercises on Muscle Strength and Endurance in Lumbar Disc Hernia
Status: COMPLETED
Conditions: Lumbar Disc Herniation
Interventions: OTHER: PNF|OTHER: lumbar stabilization training|OTHER: Physical Therapy|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of Ruxolitinib
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer|Colorectal Cancer (CRC)|Breast Cancer|Lung Cancer
Interventions: DRUG: Ruxolitinib|DRUG: Capecitabine|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Platelet Drugs and Brain-derived Neurotrophic Factor (BDNF) in Human Serum and Plasma
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DRUG: Aspirin and Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Efficacy of Dietary Flaxseed for the Reduction of Blood Pressure in Newly Diagnosed Hypertensive Individuals
Status: TERMINATED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: Flaxseed|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxytocin Versus, Sublingual Misoprostol in the Secondary Prevention of Postpartum Hemorrhage After Vaginal Delivery
Status: UNKNOWN
Conditions: Labor Complication
Interventions: DRUG: oxytocin|DRUG: misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TDCS for the Treatment of Inattention Symptoms in Adult ADHD Patients
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DEVICE: Home-based transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Benefits of Individual Physical Activity Intervention on Health-related Quality of Life in Participants With Chronic Lymphocytic Leukemia
Status: RECRUITING
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell
Interventions: BEHAVIORAL: Individual Physical Activity Intervention (IPAI)|DRUG: Ibrutinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study the Effect of Niacin on Lipoprotein (a) Concentration and Hyperphosphatemia in Hemodialysis Patients
Status: ENROLLING_BY_INVITATION
Conditions: End-stage Renal Disease
Interventions: DRUG: Niacin tablets 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CSPPT- Chronic Kidney Diseases Study
Status: WITHDRAWN
Conditions: Hypertension|Hyperhomocysteinemia
Interventions: DRUG: Enalapril maleate and folic acid tablets|DRUG: Enalapril maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Computerized Decision Support on Racial/Ethnic Disparities in Hypertension Outcomes
Status: UNKNOWN
Conditions: Hypertension
Interventions: OTHER: Computerized reminders on hypertension intensification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Innovative Approach in Tuberculosis Care in Armenia
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BEHAVIORAL: TB knowledge and socio-psychological counseling session|OTHER: SMS text messages|OTHER: phone calls|BEHAVIORAL: Self-administered drug intake strategy|BEHAVIORAL: Educational leaflet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of the Effects of Chinese Herbal Medicine on Chronic Urticaria
Status: COMPLETED
Conditions: Chronic Urticaria
Interventions: DRUG: Chinese Herbal Medicine (CHM)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Baricitinib and Simvastatin in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Baricitinib|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Manual Diaphragm Release Technique Effects On Tidal Volume in Elderly
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Sham manual diaphragm release technique|OTHER: The manual diaphragm release technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Study, Evaluating Patient Satisfaction and Symptom Improvement When Treating Male Hypogonadism With Natesto™
Status: COMPLETED
Conditions: Hypogonadism
Interventions: DRUG: NATESTO Testosterone Nasal Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Treatment Approach for Major Depressive Disorder Based Upon Targeting Monoamine Oxidase A (MAO-A)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Sertraline|DRUG: Citalopram|DRUG: N-acetylcysteine (NAC)|DRUG: Existing depression medication treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biologic Abatement and Capturing Kids' Outcomes and Flare Frequency in Juvenile Spondyloarthritis
Status: RECRUITING
Conditions: Juvenile Spondyloarthritis
Interventions: OTHER: Standard TNFi Therapy|OTHER: TNFi fixed longer dosing intervals|OTHER: Stop TNFi treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Anesthesia Care Unit (PACU) Weighted Blanket Study
Status: RECRUITING
Conditions: Cardiac Catheterization|Electrophysiology Procedure|Pediatric Cardiology
Interventions: OTHER: Standard of Care|DEVICE: Weighted blanket
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Twice Daily Application of LEO 124249 Ointment 30 mg/g in Treatment of Mild to Moderate Inverse Psoriasis
Status: COMPLETED
Conditions: Inverse Psoriasis
Interventions: DRUG: LEO 124249 ointment 30 mg/g|OTHER: LEO 124249 ointment vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Insulin Degludec/Liraglutide (A3) in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: insulin degludec|DRUG: insulin degludec/liraglutide|DRUG: liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Neramexane to Treat Congenital and Acquired Nystagmus
Status: COMPLETED
Conditions: Nystagmus, Congenital Idiopathic|Nystagmus, Acquired
Interventions: DRUG: Neramexane mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Maintenance IT-101 Therapy for Ovarian Cancer Patients.
Status: WITHDRAWN
Conditions: Cancer|Ovarian Cancer|Solid Tumor
Interventions: DRUG: IT-101 (12mg/m2/dose)|DRUG: IT-101 (15mg/m2/dose)|DRUG: 5% Dextrose (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IMX-110 in Patients With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor, Adult|Advanced Solid Tumors|Pancreatic Cancer|Breast Cancer|Ovarian Cancer
Interventions: DRUG: Imx-110
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self Transcranial Direct Current Stimulation and Mindfulness-based Meditation for Pain in Older Adults With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Self Transcranial Direct Current Stimulation (tDCS)|BEHAVIORAL: mindfulness-based meditation|DEVICE: Sham Self Transcranial Direct Current Stimulation (tDCS)|BEHAVIORAL: sham meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dociparstat for the Treatment of Severe COVID-19 in Adults at High Risk of Respiratory Failure
Status: TERMINATED
Conditions: Coronavirus Disease 2019 (COVID-19)|Acute Lung Injury|Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
Interventions: DRUG: Dociparstat sodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Double-Blinded, Randomized Controlled Trial of dHACM for Incisional Hernia Prophylaxis
Status: UNKNOWN
Conditions: Incisional Hernia
Interventions: BIOLOGICAL: dHACM (AmnioWrap)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of E-Liquid Flavor on Respiratory Symptoms in People Using Electronic Nicotine Delivery Systems
Status: RECRUITING
Conditions: Electronic Cigarette Use
Interventions: OTHER: E-cigarette Flavor|OTHER: Tobacco Free Nicotine Pouch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The HEROES Trial: Hyperbaric Oxygen Therapy for Endometriosis-Related Pain
Status: NOT_YET_RECRUITING
Conditions: Endometriosis-related Pain
Interventions: DEVICE: Monoplace Hyperbaric Chamber (Class III medical device)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Candesartan on Symptomatic Heart Failure in Treating Diabetic and Hypertensive Patients.
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Candesartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Formoterol-HFA 3-month Study in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Formoterol|DRUG: Formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Predictive Biomarkers for Rational Management of Drug-resistant Epilepsy Associated With Focal Cortical Dysplasia
Status: UNKNOWN
Conditions: Refractory Epilepsy|Focal Epilepsy|Focal Cortical Dysplasia
Interventions: PROCEDURE: visual and quantitative SEEG signal analysis|PROCEDURE: Resective epilepsy surgery procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of a Nurse-led Personalized Telephone Intervention on Lifestyle Changes in Diabetes Prevention.
Status: COMPLETED
Conditions: Prediabetic State
Interventions: BEHAVIORAL: nurse-led teleconsultation|BEHAVIORAL: SMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The POSA Trial - Positional Therapy for Positional OSA
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Positional Sleep Apnea
Interventions: DEVICE: The Night Shift™ Sleep Positioner (Advanced Brain Monitoring, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Single-Center Investigation of the da Vinci SP® Surgical System in Anterior Mediastinal Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Robotic Surgical Procedure|Thymoma|Myasthenia Gravis
Interventions: DEVICE: Da Vinci SP surgical platform
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of the Traditional Chinese Medicine Niubang Pill Combined With Methotrexate on Active Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Niu Bang Zi Pill|Rheumatoid Arthritis
Interventions: DRUG: NiuBangZi pill or NiuBangZi pill placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study With Proton Pump Inhibitor
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Atazanavir|DRUG: Atazanavir/Ritonavir|DRUG: Atazanavir/Ritonavir+Omeprazole|DRUG: Atazanavir/Ritonavir+Omeprazole|DRUG: Atazanavir|DRUG: Atazanavir/Ritonavir|DRUG: Atazanavir/Ritonavir+Omeprazole|DRUG: Atazanavir/Ritonavir+Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Comparison of Three Soft Bifocal Contact Lenses
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: balafilcon A|DEVICE: senofilcon A production|DEVICE: senofilcon A test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Protein Expression in Tumor Tissue Samples From Patients With Cancer of the Oropharynx
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: GENETIC: gene expression analysis|GENETIC: microarray analysis|GENETIC: protein expression analysis|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hepcidin Mimetic in Patients With Polycythemia Vera (REVIVE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Polycythemia Vera
Interventions: DRUG: PTG-300|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation From Biopsychosocial Perspective of Patients With Rheumatic Disease With Covid-19 Who Participated in a Biopsychosocial Exercise Program: A Case Series With 6-Month Follow-up
Status: COMPLETED
Conditions: Rheumatic Diseases
Interventions: OTHER: Bilişsel Egzersiz Terapi Yaklaşımı (BETY, Cognitive Exercise Therapy Approach)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motivational Interviewing to Promote Healthy Behaviours in Young Adults
Status: COMPLETED
Conditions: Obesity|Risk Factors
Interventions: BEHAVIORAL: Motivational interviewing|BEHAVIORAL: Educational materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Decitabine-primed Tandem CD19/CD20 CAR T Cells Treatment in r/r B-NHL
Status: RECRUITING
Conditions: Relapsed and Refractory B-cell Non-Hodgkin's Lymphoma|Decitabine-primed Tandem CD19/CD20 CAR T Cells
Interventions: BIOLOGICAL: Decitabine-primed Tandem CAR19/20 engineered T cells|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Evaluate the Safety and Tolerability of GSK1362885 in Healthy Normal Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: GSK1362885|DRUG: GSK1362885|DRUG: Glucagon|DRUG: Glucagon + GSK1362885
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study for Acarbose / Metformin FDC
Status: COMPLETED
Conditions: Diabetes Mellitus, Type II
Interventions: DRUG: Acarbose/Metformin FDC (BAY81-9783)|DRUG: Acarbose (Glucobay, BAYG5421)|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Hydrocortisone 50 mg Every 6 Hours Compared to Hydrocortisone 300 mg Per Day in Treatment of Septic Shock.
Status: COMPLETED
Conditions: Septic Shock
Interventions: DRUG: Hydrocortisone hemisuccinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AURORA: A Study for the Efficacy and Safety of Cenicriviroc (CVC) for the Treatment of Liver Fibrosis in Adults With Nonalcoholic Steatohepatitis (NASH)
Status: TERMINATED
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: Placebo|DRUG: Cenicriviroc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children
Status: COMPLETED
Conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Acute Biphenotypic Leukemia|Acute Leukemia of Ambiguous Lineage|Acute Undifferentiated Leukemia|Adult Acute Lymphoblastic Leukemia in Remission|Adult Acute Myeloid Leukemia in Remission|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Childhood Acute Lymphoblastic Leukemia in Remission|Childhood Acute Myeloid Leukemia in Remission|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Myelodysplastic Syndrome With Excess Blasts-1|Myelodysplastic Syndrome With Excess Blasts-2|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Refractory Adult Acute Lymphoblastic Leukemia|Refractory Childhood Acute Lymphoblastic Leukemia
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|DRUG: Methotrexate|PROCEDURE: Peripheral Blood Stem Cell Transplantation|BIOLOGICAL: T Cell-Depleted Hematopoietic Stem Cell Transplantation|DRUG: Tacrolimus|DRUG: Thiotepa|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monitored Breathing Awareness Therapy for Insomnia Disorder in Older Adults-2
Status: ACTIVE_NOT_RECRUITING
Conditions: Insomnia
Interventions: BEHAVIORAL: Sleep education and relaxation 1|BEHAVIORAL: Sleep education and relaxation 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pediatric Adenotonsillectomy Trial for Snoring
Status: COMPLETED
Conditions: Sleep-Disordered Breathing
Interventions: PROCEDURE: Early Adenotonsillectomy (eAT)|BEHAVIORAL: Watchful Waiting with Supportive Care (WWSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-cohort Study of the Tolerance, Safety, and Pharmacokinetics of GNR-055 in Healthy Volunteers
Status: COMPLETED
Conditions: Mucopolysaccharidosis Type II|Metabolic Diseases
Interventions: BIOLOGICAL: GNR-055
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transdiagnostic Group Cognitive Behavioral Therapy (PsicAP-A) for Adolescents With Emotional Disorders
Status: UNKNOWN
Conditions: Emotional Disorder
Interventions: BEHAVIORAL: 7 sessions (1.5 hr/session) in groups of approximately 8-10 individuals|BEHAVIORAL: a progressive muscle relaxation group intervention, based on the Bernstein and Borkoveck procedure plus same number of sessions as the experimental intervention.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Tendon Injury Using Mesenchymal Stem Cells
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: BIOLOGICAL: ALLO-ASC(allogeneic adipose derived mesenchymal stem cell) injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Transition Outcomes for Youth With ASD in a Medicaid Accountable Care Organization
Status: WITHDRAWN
Conditions: Autism Spectrum Disorder
Interventions: OTHER: Usual care|OTHER: 'Got Transition' toolkit and resources|BEHAVIORAL: PSE intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study Comparing Amounts of Tafamidis In The Blood With Or Without Food
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: tafamidis|DRUG: tafamidis|DRUG: tafamidis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ceritinib and Combination Chemotherapy in Treating Patients With Advanced Solid Tumors or Locally Advanced or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Advanced Malignant Solid Neoplasm|ALK Positive|Metastatic Pancreatic Adenocarcinoma|Stage III Pancreatic Cancer|Stage IV Pancreatic Cancer
Interventions: DRUG: Ceritinib|DRUG: Cisplatin|DRUG: Gemcitabine Hydrochloride|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel Albumin-Stabilized Nanoparticle Formulation|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resistance Training and Protein Supplementation for Prostate Cancer Survivors
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: exercise intervention|DIETARY_SUPPLEMENT: nutritional supplementation|PROCEDURE: quality-of-life assessment|OTHER: questionnaire administration|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transcranial Direct Current Stimulation of the Primary Motor Cortex to Treat Levodopa-induced Dyskinesias
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Contralateral Arytenoid Sparing IMRT for T1a & T2a Larynx Cancer & Analysis of Post-treatment Laryngeal Function
Status: TERMINATED
Conditions: Laryngeal Neoplasms
Interventions: RADIATION: IMRT Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel Versus Cabazitaxel Post Abiraterone or Enzalutamide
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: Cabazitaxel plus prednisone|DRUG: Docetaxel plus prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of SAM-315 in Healthy Adults
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: SAM-315
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Addition of Metronomic Capecitabine to Standard Adjuvant Therapy in High Risk HER2+ BC paTients
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics For The Prevention of Antibiotics Associated Diarrhea in the Pediatric Intensive Care Unit
Status: COMPLETED
Conditions: Critical Illness|Antibiotic-associated Diarrhea
Interventions: DIETARY_SUPPLEMENT: lactobacillus GG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PCI-32765 (Ibrutinib) in Combination With Either Bendamustine and Rituximab or Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Participants With Previously Treated Indolent Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Bendamustine|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|DRUG: PCI-32765 (Ibrutinib)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of a Bone Assessment Technique, Bone Mineral Analyser, Concerning the Prediction of Improvement in Bone Status After an Infusion of Zoledronic Acid in Osteoporotic Women
Status: UNKNOWN
Conditions: Osteoporosis
Interventions: DIAGNOSTIC_TEST: Bone mineral analyser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Glucocorticoid Induced Whole Body Catabolisme
Status: COMPLETED
Conditions: Whole Body Catabolisme Induced by Glucocorticoids
Interventions: DRUG: Glucocorticoids|DRUG: Calcium Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Psycho-emotional Support in Acute Spinal Cord Injury. ESPELMA Project
Status: COMPLETED
Conditions: Spinal Cord Injury, Acute|Professional-Patient Relations|Sensitivity Training Groups|Patient Non-Compliance|Satisfaction
Interventions: BEHAVIORAL: Training for professionals (Spinal Cord Injury Unit staff).
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Acamprosate in the Treatment of Binge-Eating Disorder
Status: COMPLETED
Conditions: Binge Eating Disorder
Interventions: DRUG: acamprosate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Pembrolizumab and Olaparib for People With Metastatic Pancreatic Ductal Adenocarcinoma and Homologous Recombination Deficiency or Exceptional Treatment Response to Platinum-Based Therapy
Status: RECRUITING
Conditions: Metastatic Pancreatic Ductal Adenocarcinoma|Homologous Recombination Deficiency (HRD)
Interventions: DRUG: Pembrolizumab|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Effect of Limicol on (LDL)-Cholesterol Levels
Status: COMPLETED
Conditions: Hypercholesterolaemia
Interventions: DIETARY_SUPPLEMENT: Limicol|DIETARY_SUPPLEMENT: Limicol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LPS Flex Porous Femoral Components
Status: WITHDRAWN
Conditions: Osteoarthritis|Rheumatoid Arthritis|Traumatic Arthritis|Poly Arthritis|Collagen Disorders|Avascular Necrosis of Femoral Condyle
Interventions: DEVICE: LPS Flex Porous Femoral Components
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Placebo Controlled Study to Generate Data Characterising Safety Parameters and Immune Responses
Status: COMPLETED
Conditions: Prevention of Infections With Bordetella Pertussis
Interventions: BIOLOGICAL: Boostrix|BIOLOGICAL: Placebo (Saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Value of Breast High-Resolution MR Ductography in Patients With Pathological Nipple Discharge
Status: RECRUITING
Conditions: Breast Neoplasms|Nipple Discharge
Interventions: DIAGNOSTIC_TEST: Magnetic Resonance Ductography (MRD); and High-Resolution Magnetic Resonance Ductography (HR-MRD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nebulized Dexmedetomidine Versus Oral Sumatriptan in Treatment of Post Dural Puncture Headache in Cesarean Section
Status: RECRUITING
Conditions: Post-Dural Puncture Headache
Interventions: DRUG: Precedex|DRUG: Sumatriptan 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability, Efficacy and QoL Study of Human recAP in the Treatment of Patients With SA-AKI
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: BIOLOGICAL: recAP|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging of GSK2336805 in Combination Therapy
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: GSK2336805 40 mg|DRUG: GSK2336805 60 mg|DRUG: Pegylated interferon alpha-2a|DRUG: Ribavirin|DRUG: Telaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Anti-HIV Treatment Strategies in Resource-Limited South African Communities
Status: COMPLETED
Conditions: HIV Infections
Interventions: BEHAVIORAL: Monitoring by an HIV-trained medical doctor|BEHAVIORAL: Monitoring by an HIV-trained primary care nurse|DRUG: Efavirenz|DRUG: Lamivudine|DRUG: Lopinavir/Ritonavir|DRUG: Nevirapine|DRUG: Stavudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Nicotine Patch in Suppressing Nicotine Withdrawal Symptoms in Women Versus Men - 1
Status: COMPLETED
Conditions: Smoking Cessation|Tobacco Use Disorder
Interventions: DRUG: nicotine transdermal system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine, Oxaliplatin and Capecitabine for Advanced Pancreatic Carcinoma
Status: COMPLETED
Conditions: Locally Advanced Pancreatic Cancer|Metastatic Pancreatic Cancer
Interventions: DRUG: gemcitabine, oxaliplatin, capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lamelleye vs Comparator for the Treatment of Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DEVICE: Lamelleye Dry Eye Drops|DEVICE: Optive Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Mild Sedation on Motor Function Networks in Patients With Brian Gliomas
Status: RECRUITING
Conditions: Brain Glioma
Interventions: DRUG: Midazolam|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Adductor Canal Block for Total Knee Arthroplasty Surgery
Status: WITHDRAWN
Conditions: Knee Osteoarthritis|Knee Arthropathy|Knee Pain Chronic|Knee Deformity|Knee Disease
Interventions: DRUG: Postoperative analgesia management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Two Different Commercial EV71 Vaccines
Status: COMPLETED
Conditions: Hand, Foot and Mouth Disease
Interventions: BIOLOGICAL: EV71 inactived vaccine（Vero cells）|BIOLOGICAL: EV71 inactived vaccine（Human diploid cells）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Subcutaneous NTG for US Radial Artery Cannulation
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: DRUG: Subcutaneous nitroglycrin|DRUG: Subcutaneous saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Evaluate the Safety, Tolerability, and Pharmacokinetics of INS018_055 in Healthy Subjects
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: INS018_055|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Monitoring of Patients With Cardiac Amyloidosis With Implantable Event Monitors
Status: COMPLETED
Conditions: TTR Cardiac Amyloidosis
Interventions: DEVICE: Biotronik Biomonitor 3 implant of device|DEVICE: Biotronik Biomonitor 3 explant of device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Optimization of Vonoprazan-based Dual Therapy for Helicobacter Pylori
Status: ACTIVE_NOT_RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Vonoprazan|DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-CD19 Universal CAR-T Cells for r/r CD19+ B-ALL
Status: WITHDRAWN
Conditions: B-cell Acute Lymphoblastic Leukemia|B-ALL
Interventions: BIOLOGICAL: U-CAR-T Cells (LstCAR019)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dry Needling and Shoulder Muscle Blood Flow, Motions, and Pain Sensitivity in Individuals With Shoulder Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Dry Needling|Shoulder Pain
Interventions: OTHER: Dry Needling|OTHER: Sham Dry Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: WD-1603 PK Study Under Fasting and Fed Conditions in Healthy Subjects
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DRUG: WD-1603 CARBIDOPA and LEVODOPA EXTENDED-RELEASE TABLETS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acetaminophen/Naproxen Sodium Dose Ranging Study
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Acetaminophen/naproxen sodium Dose A|DRUG: Acetaminophen/naproxen sodium Dose B|DRUG: Acetaminophen/naproxen sodium Dose C|DRUG: Acetaminophen/naproxen sodium Dose D|DRUG: Acetaminophen/naproxen sodium Dose E|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcome of Pulp Revascularization of Necrotic Mature Permanent Teeth Using Platelet-rich Fibrin
Status: RECRUITING
Conditions: Pulp Revascularization
Interventions: BIOLOGICAL: induced bleeding|BIOLOGICAL: plasma rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Characteristics and Treatment of Anosmia and Ageusia Due to SARS-CoV2 Variants
Status: COMPLETED
Conditions: Post-covid-19 Persistent Smell and Taste Disorders
Interventions: DRUG: Cerebrolysin|OTHER: olfactory and gustatory trainings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Danvatirsen Monotherapy Followed by Combination With Venetoclax in Relapsed/Refractory MDS & AML
Status: RECRUITING
Conditions: AML/MDS|Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: Danvatirsen|COMBINATION_PRODUCT: Danvatirsen + Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sector Irradiation Versus Whole Brain Irradiation for Brain Metastasis
Status: UNKNOWN
Conditions: Metastatic Malignant Neoplasm to the Adult Brain
Interventions: RADIATION: sector irradiation|RADIATION: whole brain irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Topical Hyaluronic Acid and Laser Application on Wound Healing in Children
Status: ENROLLING_BY_INVITATION
Conditions: Wound Heal|Tooth Extraction Status Nos
Interventions: DRUG: Hyaluronic Acid Topical Gels|PROCEDURE: Diode Laser Biostimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of AMG0001 to Improve Ulcer Healing and Perfusion in Subjects With Peripheral Ischemic Ulcers
Status: UNKNOWN
Conditions: Peripheral Artery Disease|Ischaemic Ulcer of Lower Leg Due to Atherosclerotic Disease|Chronic Limb Threatening Ischemia|Ischemic Ulcer of Foot
Interventions: BIOLOGICAL: AMG0001|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sleepiz One+ vs. Capnography and Electrocardiography
Status: RECRUITING
Conditions: Sleep Apnea|Asthma|COPD|Hypertension|Diabetes|Respiratory Disease|Cardiovascular Diseases
Interventions: DEVICE: Sleepiz One+
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Re-Treatment With MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to a Single Anti-TNF Inhibitor.
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: rituximab [MabThera/Rituxan]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RC48-ADC Combined With Pyrotinib For Treatment of Local Advanced or Metastasis NSCLC With HER2 Mutation
Status: NOT_YET_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: RC48-ADC|DRUG: Pyrotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tiotropium Respimat Versus HandiHaler on SaO2 and Sleep in COPD Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: tiotropium|DEVICE: Handihaler|DEVICE: Respimat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcatheter Heart Valve (THV) Sizing and Leakage After Transcatheter Aortic Valve Implantation (TAVI) Before and After Establishing Routine Preprocedure Multi Slice Computerized Tomography (MSCT) Aortic Assessment. A Retrospective Registry Study
Status: COMPLETED
Conditions: Aortic Stenosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stellate Ganglion Block (SGB) for COVID-19 Acute Respiratory Distress Syndrome (ARDS)
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|COVID-19
Interventions: PROCEDURE: Stellate Ganglion Block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yttrium-90 Carbon Microspheres in Patients With Unresectable Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Unresectable Hepatocellular Carcinoma
Interventions: COMBINATION_PRODUCT: Yttrium-90 carbon microspheres SIRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Transmuscular Quadratus Lumborum Block for Percutaneous Nephrolithotomy
Status: COMPLETED
Conditions: Kidney Stone
Interventions: PROCEDURE: Ropivacaine TQL block|PROCEDURE: Saline TQL block|DRUG: Ropivacaine|DRUG: Saline|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Faciltiation of Swallowing in Patients With Severe Dysphagia After Acquired Brain Injury
Status: COMPLETED
Conditions: Deglutition Disorders
Interventions: OTHER: Intensive F.O.T.T.®|OTHER: Unspecific Stimulation of face and mouth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT