pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of [68Ga]GaFAPI-46 PET/CT and [18F]FDG PET/CT Findings in Breast Carcinoma
Status: UNKNOWN
Conditions: Breast Neoplasms|Positron Emission Tomography|Fibroblast Activation Protein Inhibitor|Fluorodeoxyglucose F18
Interventions: DIAGNOSTIC_TEST: 68Ga-FAPI-46 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Effects of Selpercatinib (LY3527723) on Repaglinide in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Repaglinide|DRUG: Selpercatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study on the Optimal Strategy of Chinese Patients With Bulimia Nervosa After Fluoxetine Treatment
Status: UNKNOWN
Conditions: Fluoxetine
Interventions: DRUG: Topiramate|DRUG: Fluoxetine|BEHAVIORAL: cognitive behavioral therapy (CBT)|BEHAVIORAL: dialectical behavior therapy (DBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose and Multiple Dose Safety, Tolerability, PK，and Food Effect Study，and Interaction With Oseltamivir Study of HEC116094 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: HEC116094
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HP Arize 3D Orthotics for Planar Fasciitis
Status: ENROLLING_BY_INVITATION
Conditions: Plantar Fascitis
Interventions: DEVICE: HP Arize 3D-Printed Orthotics|DEVICE: Traditional Orthotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation Treatment for Chorea in Huntington's Disease
Status: UNKNOWN
Conditions: Huntington Disease|Deep Brain Stimulation
Interventions: DEVICE: Deep brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Ultrasound(EUS)-Guided TRUCUT Biopsy (EUS-TCB) of Suspected Nonalcoholic Fatty Liver Disease(NAFLD.)
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease|Nonalcoholic Steatohepatitis
Interventions: DEVICE: Tru-cut biopsy|PROCEDURE: Tru-cut
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Physical Activity in Persons With Charcot-Marie-Tooth: Developing a Measurement Instrument
Status: UNKNOWN
Conditions: Hereditary Motor and Sensory Neuropathy|Charcot-Marie-Tooth|Polyneuropathies
Interventions: OTHER: Original IPAQ followed by a revised one.|OTHER: Revised IPAQ followed by an original one.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Diagnostic Accuracy of Circulating Tumor Cells (CTCs) and Onco-exosome Quantification in the Diagnosis of Pancreatic Cancer - PANC-CTC
Status: COMPLETED
Conditions: Pancreatic Ductal Adenocarcinoma (PDAC)
Interventions: PROCEDURE: Blood samples|PROCEDURE: Portal vein blood sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Therapeutic Effects Analysis of Pudendal Nerve Infiltrations After 3 Months, in Patients Suffering of Pudendal Neuralgia
Status: COMPLETED
Conditions: Pudendal Neuralgia|Canal Syndrome
Interventions: DRUG: Lidocaine|DRUG: Depmedrol|OTHER: physiological serum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurodynamics vs. Stretching in Soccer Players With Short Hamstring Syndrome
Status: COMPLETED
Conditions: Hamstring Contractures
Interventions: PROCEDURE: Sciatic nerve slippage.|PROCEDURE: Passive stretching of the hamstring muscles.|PROCEDURE: passive shoulder mobilization.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Triage Options After HPV Testing for Cervical Cancer Screening Among HIV-infected Women
Status: UNKNOWN
Conditions: HIV Infections|HPV - Anogenital Human Papilloma Virus Infection
Interventions: DIAGNOSTIC_TEST: HPV test with partial genotyping and VIA triage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: LUMBAR MULTIFIDUS MUSCLES FUNCTION AMONG PATIENTS WITH LOW BACK PAIN: VIRTUAL REALITY VERSUS STABILIZATION EXERCISES.
Status: COMPLETED
Conditions: Low Back Pain|Low Back Pain, Mechanical
Interventions: DEVICE: VIRTUAL REALITY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Facial Bone Changes After Early Implant Placement Protocols "Clinically and Radiographically".
Status: ACTIVE_NOT_RECRUITING
Conditions: Bone Loss|Dental Implants
Interventions: PROCEDURE: Early implant placement(type II)|PROCEDURE: Early implant placement (type III)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Adelbelimab Combination Chemotherapy in Neoadjuvant Therapy for Squamous Cell Carcinoma of the Head and Neck
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Nab paclitaxel|DRUG: Carboplatin|DRUG: adelbelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alcohol Use Disorders in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Mood Disorders|Alcohol Abuse|Alcohol Dependence
Interventions: BEHAVIORAL: Supportive Treatment in Addiction Recovery (STAR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of Seasonique for the Treatment of Cyclic Pelvic Pain
Status: COMPLETED
Conditions: Dysmenorrhea
Interventions: DRUG: levonorgestrel/EE 0.15/0.03 and EE 0.01 mg tablets|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Mecobalamin Injection in Peripheral Neuropathies Patients (Study JGAZSY091109)
Status: COMPLETED
Conditions: Peripheral Neuropathy
Interventions: DRUG: Mecobalamin IV Injection|DRUG: Mecobalamin IM injection|DRUG: Mecobalamin IV or IM injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Administration of an Oral Anti-thrombotic With Antiplatelet Therapy in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BMS-986177|OTHER: Placebo (for BMS-986177)|DRUG: Clopidogrel|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Increasing Dose Safety and Tolerability Study After Inhalation Administration of BIIX 1 XX in Healthy Male Volunteers
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: BIIX 1 XX - D1|DRUG: BIIX 1 XX - D2|DRUG: BIIX 1 XX - D3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: NAC Treatment and Outcomes in Patients With Advanced Atherosclerosis and DM
Status: WITHDRAWN
Conditions: Atherosclerosis of Artery|Peripheral Artery Disease|Diabetes Mellitus|Inflammation|Oxidative Stress
Interventions: DRUG: N-acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fed Study of Midodrine HCl Tablets 5 mg and ProAmatine® Tablets 5 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Midodrine HCl Tablets 5 mg|DRUG: ProAmatine® Tablets 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Assess the Long-term Safety, Tolerability, Efficacy of Secukinumab in Pediatric Patients of Age 6 to <18 Years, With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Moderate to Severe Chronic Plaque-type Psoriasis
Interventions: DRUG: secukinumab low dose|DRUG: secukinumab high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study on Traditional Chinese Medicine and Food Allergy
Status: TERMINATED
Conditions: Allergy to Fish|Allergy to Shrimp|Allergy to Crab
Interventions: DIETARY_SUPPLEMENT: Treatment - Chinese Herbal Formula - X|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Shuxuetong for Prevention of Recurrence in Acute Cerebrovascular Events With Embolism
Status: COMPLETED
Conditions: Embolic Stroke
Interventions: DRUG: Shuxuetong Injection|DRUG: Placebo Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Baricitinib in Oral Lichen Planus: a Proof-of-Concept Study
Status: RECRUITING
Conditions: Lichen Planus, Oral|Lichen Planus, Mucosal|Oral Lichen Planus
Interventions: DRUG: Baricitinib 4 milligram Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Automated and Manual Component Impaction in Total Hip Arthroplasty
Status: COMPLETED
Conditions: Total Hip Arthroplasty (THA)
Interventions: DEVICE: Automated KINCISE™ impaction system versus handheld traditional mallet|OTHER: Efficiency and ergonomics analysis and physical assessments
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Advance Care Planning and Care Coordination for People With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Parkinsonism
Interventions: BEHAVIORAL: PD_Pal intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial Investigating the Efficacy of the Supera Peripheral Stent System for the Treatment of the Common Femoral Artery
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Supera Peripheral Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of D-allulose in Addition to Oral Sucrose Load
Status: COMPLETED
Conditions: Blood Glucose
Interventions: DIETARY_SUPPLEMENT: D-allulose|DIETARY_SUPPLEMENT: sucrose|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Corticosteroids in U-5 Children With Acute Respiratory Infection in Uganda: A Randomised Trial
Status: COMPLETED
Conditions: Bacterial Pneumonia|Viral Pneumonia|Acute Asthma
Interventions: DRUG: Inhaled corticosteroid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Combining SAR245409 With Rituximab or Bendamustine Plus Rituximab in Patients With Indolent Lymphoma, Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Indolent Non-Hodgkin Lymphoma|Mantle Cell Lymphoma|Chronic Lymphocytic Leukemia
Interventions: DRUG: SAR245409
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transthoracic Ultrasonography Findings and Their Relation to Spirometric Indices in Patients With Obstructive and Restrictive Respiratory Diseases
Status: RECRUITING
Conditions: Lung Ultrasound|Spirometry|Respiratory Diseases|Diaphragm Ultrasound
Interventions: RADIATION: transthoracic ultrasonography|DEVICE: spirometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Facilitation of Brain Plasticity for Language Recovery in Patients With Aphasia Due to Stroke
Status: UNKNOWN
Conditions: Stroke|Aphasia
Interventions: DEVICE: experimental: tDCS|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Pharmacodynamic Analysis of Ceftaroline in Children and Adolescents With Cystic Fibrosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Cystic Fibrosis
Interventions: DRUG: Ceftaroline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessement of the Peal Force Needed to Peel New Adhesives From the Skin
Status: COMPLETED
Conditions: Ileostomy - Stoma
Interventions: OTHER: Standard adhesive 1|OTHER: Standard adhesive 2|OTHER: LT-2|OTHER: LT-21|OTHER: LT-25|OTHER: 33-20
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of Suvorexant on Sympathetic Nerve Activity and Baroreflex Function in Chronic Insomnia
Status: UNKNOWN
Conditions: Chronic Insomnia
Interventions: DRUG: Suvorexant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Once Monthly Subcutaneous Mircera in Dialysis Patients With Chronic Renal Anemia
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: methoxy polyethylene glycol-epoetin beta [Mircera]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the 24 Hour Spirometric Effect (FEV1) of Fluticasone Furoate/Vilanterol Inhalation Powder (100mcg Fluticasone Furoate (FF)/25mcg Vilanterol (VI)) Compared With Salmeterol/Fluticasone Propionate Inhalation Powder (50mcg Salmeterol/500mcg Fluticasone Propionate (FP))
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Fluticasone Furoate 100mcg/Vilanterol 25mcg|DRUG: Fluticaosne Propionate 500mcg/Salmeterol 50mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Building Employment Skills Through Therapy for Veterans
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: integrated Cognitive Behavioral Therapy|OTHER: Usual Care|BEHAVIORAL: Computerized cognitive remediation (CCR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacist-Led Hospital-Based Intervention to Support Medication Adherence Following Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: BEHAVIORAL: Intervention cohort ('after' group)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REACH-Es: Adapting a Digital Health Tool to Improve Diabetes Medication Adherence Among Latino Adults
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes (Adult Onset)|Medication Adherence
Interventions: BEHAVIORAL: REACH-Es|BEHAVIORAL: ETAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Metformin and Cholecystokinin-mediated Gallbladder Emptying on GLP-1 Secretion in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Isotonic saline|DRUG: Metformin placebo|DRUG: Cholecystokinin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Trial of Retinal Gene Therapy for X-linked Retinitis Pigmentosa Using BIIB112
Status: COMPLETED
Conditions: X-Linked Retinitis Pigmentosa
Interventions: BIOLOGICAL: BIIB112
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare Visual Field Impairment in Conventional Double Frequency Nd: YAG Panretinal Photocoagulation With PASCAL Panretinal Photocoagulation
Status: UNKNOWN
Conditions: Macular Edema|Diabetic Retinopathy|Visual Field Loss
Interventions: PROCEDURE: PASCAL laser|PROCEDURE: Conventional laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Botulinum Toxin Treatment in Quality of Life of Cervical Dystonia Patients
Status: UNKNOWN
Conditions: Botulinum Toxin|Quality of Life|Cervical Dystonia
Interventions: DRUG: Nuronox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation by Magnetic Resonance Imaging of Intramuscular Injections Performance in Thigh With 2 Configurations of the Needle-free Injector ZENEO®.
Status: COMPLETED
Conditions: Needle-free Injector
Interventions: COMBINATION_PRODUCT: Injections in thigh of 0.625 mL of physiological serum with ZENEO® injector, on bare skin and through clothing.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: carmustine|DRUG: cisplatin|DRUG: melphalan|DRUG: paclitaxel|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: surgical procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Patient Controlled Administration of Liquid Acetaminophen
Status: NOT_YET_RECRUITING
Conditions: Pain|Pain, Postoperative
Interventions: DRUG: Acetaminophen 650 mg Oral Tablet|DRUG: Acetaminophen 650mg Liquid|DEVICE: CADD pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 26-Week Extension Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy
Status: COMPLETED
Conditions: Schizophrenia|Impaired Cognition
Interventions: DRUG: EVP-6124
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sustained Natural Apophyseal Glide and Deep Friction Massage in Patients With Cervicogenic Headache
Status: COMPLETED
Conditions: Headache Disorders
Interventions: OTHER: sustained natural apophyseal glide|OTHER: deep friction massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remotely Monitored Exercise Interventions in Patients With mCSPC Undergoing ADT (Prostate 006)
Status: RECRUITING
Conditions: Castrate Sensitive Prostate Cancer|Metastatic Prostate Cancer
Interventions: BEHAVIORAL: Home-Based Exercise Intervention - Walking|BEHAVIORAL: Home-Based Exercise Intervention - HIIT Cycling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cardiac Metabolic Modulator Treatment for Improvement of Diastolic Function in Patients With Coronary Heart Disease
Status: UNKNOWN
Conditions: Coronary Heart Disease|Diastolic Dysfunction
Interventions: DRUG: Trimetazidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radioactive Stents for Treatment of Unresectable Biliary Tract Cancer
Status: UNKNOWN
Conditions: Intrahepatic Cholangiocarcinoma|Cholangiocarcinoma of the Extrahepatic Bile Duct|Ampullary Carcinoma|Biliary Obstruction
Interventions: DEVICE: radioactive stent|DEVICE: plastic stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genicular Nerve Block for Total Knee Arthroplasty
Status: COMPLETED
Conditions: Post-operative Pain
Interventions: DRUG: 15mL 0.25% bupivacaine|PROCEDURE: Genicular nerve block|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Volume Restriction in Esophageal Carcinoma Surgery: Randomized Clinical Trial
Status: COMPLETED
Conditions: Esophageal Neoplasm
Interventions: OTHER: Restrictive group|OTHER: Liberal group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Everolimus Combined With Anti-estrogen Therapy in Hormone-Receptor-Positive HER-2 Negative Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Everolimus|DRUG: Exemestane|DRUG: Tamoxifen|DRUG: Fulvestrant|DRUG: Anastrozole|DRUG: Letrozole|DRUG: Toremifine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicentre Randomized Controlled Clinical Study on the Chitosan Nanocrystalline Qinteng Huoxue Runji Ointment Therapy for Psoriasis With Blood Stasis Syndrome.
Status: NOT_YET_RECRUITING
Conditions: Plaque Psoriasis
Interventions: DRUG: Chitosan Nanocrystalline Qinteng Huoxue Runji Ointment|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Specific miRNA Encoded by SARS-CoV-2 as a Diagnostic Tool to Predict Disease Severity in COVID-19 Patients
Status: COMPLETED
Conditions: COVID-19
Interventions: DIAGNOSTIC_TEST: miRNA analysis in plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study of Docetaxel/Gemcitabine Followed by Chemo-radiotherapy (Chemo-RT), With or Without Consolidation Chemotherapy, in IIIA/IIIB Non Small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Docetaxel|DRUG: Gemcitabine|DRUG: Carboplatin|RADIATION: Chemoradiotherapy|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of 3 Different Bowel Cleansing Preparations
Status: COMPLETED
Conditions: Colonoscopy|Bowel Preparation|Endoscopy
Interventions: DRUG: PEG-3350 based bowel preparation|DRUG: BLI800 approved preparation regimen|DRUG: BLI800 investigational preparation regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SYNERGIC-2 Trial (SYNchronizing, Exercises and Remedies to GaIn Cognition@Home)
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: OTHER: PMI@Home|OTHER: Brain Health Pro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 18F-DOPA PET to Elucidate the Antidepressant Mechanism of Lurasidone in Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Depression
Interventions: DRUG: Lurasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Non Alcoholic Fatty Liver Disease With n-3 Fatty Acids
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DRUG: OMACOR|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Changes of ONSD Between Groups of Laparoscopic Surgery With and Without Epidural Saline Injection
Status: UNKNOWN
Conditions: Optic Nerve Sheath Diameter|Pneumoperitoneum|Epidural
Interventions: PROCEDURE: Epidural injection through thoracic epidural catheter|PROCEDURE: Without epidural injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The International Diabetes Closed Loop (iDCL) Trial: Clinical Acceptance of the Artificial Pancreas
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: t:slim X2 with Control-IQ Technology & Dexcom G6 CGM|DEVICE: Sensor-augmented pump (SAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of the Effect of BIIB023 on Muscle Atrophy in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: BIIB023|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of In-Stent Restenosis 2 Study
Status: COMPLETED
Conditions: Coronary Restenosis
Interventions: COMBINATION_PRODUCT: sirolimus-eluting balloon (SEB) MagicTouch|COMBINATION_PRODUCT: paclitaxel-eluting balloon (PEB) Sequent Please
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Measuring of Neuro-visual Functionality With Ocusweep
Status: UNKNOWN
Conditions: Visual Impairment
Interventions: DEVICE: Ocusweep|DEVICE: Ocusweep OcuRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nonopioid Analgesics and Cholecystectomy
Status: COMPLETED
Conditions: Cholecystectomy|Pain, Postoperative|Opioid Use
Interventions: DRUG: nefopam, ketoprofen, paracetamol|DRUG: saline infusion, ketoprofen, paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Lung Ultrasound in Pediatric Patients
Status: COMPLETED
Conditions: Ultrasonography|Pediatrics|Perioperative Period|Lung|Cardiac Surgical Procedures
Interventions: DEVICE: Lung ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Evaluate the Effect of Wound Infiltration With Bupivacaine for Post-operative Pain Relief After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Post-operative Pain
Interventions: DRUG: Bupivacaine|DRUG: 0.9% normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Immune Modulation of Bilateral Paravertebral Block and Propofol in Spine Surgery.
Status: COMPLETED
Conditions: Immune Suppression
Interventions: DRUG: Total intravenous anesthesia group|DRUG: Total intravenous plus block group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevention of Pre-eclampsia Using Metformin: a Randomized Control Trial
Status: UNKNOWN
Conditions: Preeclampsia|Preeclampsia Severe|High Risk Pregnancy|Eclampsia
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Upper Limb Treatment With "Gloreha Aria" in the Hemiplegic Patients
Status: COMPLETED
Conditions: Hemiplegia and/or Hemiparesis Following Stroke|Upper Extremity Injury
Interventions: DEVICE: Gloreha Aria|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antibody Persistence and Booster Dose Response in Subjects Who Received Menactra® Three Years Earlier in Study MTA26
Status: COMPLETED
Conditions: Meningitis|Meningococcemia
Interventions: BIOLOGICAL: Meningococcal polysaccharide diphtheria toxoid conjugate|BIOLOGICAL: Meningococcal polysaccharide diphtheria toxoid conjugate|BIOLOGICAL: Meningococcal polysaccharide diphtheria toxoid conjugate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Development and Validation of a Predictive Score for Surgical Site Infections
Status: RECRUITING
Conditions: Colon or Colorectal Resection|Partial or Total Gastrectomy|Pancreaticoduodenectomy|Hepatectomy
Interventions: BIOLOGICAL: Peripheral venous blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Novel Targeted Drugs Combined With R-ICE Regimen in Relapsed and Refractory Diffuse Large B-cell Lymphoma
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Zanubrutinib plus R-ICE|DRUG: Decitabine plus R-ICE|DRUG: Chidamide plus R-ICE|DRUG: Tofacitinib plus R-ICE|DRUG: Pomalidomide plus R-ICE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-up Study to Investigate the Effect of GSK2245035 on Nasal Allergic Reactivity in Subjects Completing Treatment in Study TL7116958
Status: COMPLETED
Conditions: Asthma and Rhinitis
Interventions: OTHER: Pollen allergen extract
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Human Papilloma Virus Vaccine Immunogenicity and Safety Trial in Young Adult Women With GSK Bio's Novel HPV Vaccine.
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: HPV 16/18 L1 AS04|BIOLOGICAL: HPV-16/18/31/45 L1 AS04 Formulation 1|BIOLOGICAL: HPV-16/18/31/45 L1 AS04 Formulation 2|BIOLOGICAL: HPV-16/18/31/45 L1 AS04 Formulation 3|BIOLOGICAL: HPV-16/18/31/45 L1 AS04 Formulation 4|BIOLOGICAL: HPV-16/18/31/45 L1 AS04 Formulation 5|BIOLOGICAL: HPV-16/18/31/45 L1 AS04 Formulation 6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Apixaban For Thromboprophylaxis In Patients With Acute Spinal Cord Injury
Status: TERMINATED
Conditions: Spinal Cord Injuries|Venous Thromboembolism
Interventions: DRUG: Apixaban|DRUG: Low molecular weight heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Does COVID-19 Infection Increase the Risk of Pulmonary Embolism?
Status: UNKNOWN
Conditions: Covid19|Pulmonary Embolism
Interventions: DIAGNOSTIC_TEST: Exposure: Positive COVID-19 infection|DIAGNOSTIC_TEST: Exposure: Negative COVID-19 infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Magnesium Sulphate on Coagulation
Status: COMPLETED
Conditions: Myoma
Interventions: DRUG: Magnesium Sulfate|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Open-label Study of Cenobamate Monotherapy in Adult Subjects With Newly Diagnosed or Recurrent Partial-Onset Epilepsy
Status: RECRUITING
Conditions: Focal Onset Seizure
Interventions: DRUG: Cenobamate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Markers Predict Effect of Normobaric Hypoxia at Rest and During Exercise in Patients With Pulmonary Hypertension
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: OTHER: Normobaric hypoxia (FiO2 15%)|OTHER: Placebo-ambient air (FiO2 21%)|OTHER: Normobaric hypoxia (FiO2 15%) under Sildenafil|OTHER: Placebo-ambient air (FiO2 21%) under Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Efficacy and Safety of DR-3001 in Women With Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: DR-3001|DRUG: DR-3001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adenosine as an Adjunct to Blood Cardioplegia
Status: UNKNOWN
Conditions: Pathological Processes|Cardiomyopathies
Interventions: DRUG: Adenosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Levofloxacin-Doxycycline for Helicobacter Pylori Eradication in Saudi Arabia
Status: COMPLETED
Conditions: GASTRITIS
Interventions: DRUG: Levofloxacin|DRUG: Doxycycline|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Uterine Cooling During Cesarean Delivery to Reduce Blood Loss and Incidence of Postpartum Hemorrhage
Status: COMPLETED
Conditions: Postpartum Hemorrhage|Uterine Atony
Interventions: PROCEDURE: Uterine Cooling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Parameters of Exercise to Prevent Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: BEHAVIORAL: Experimental: 40 minute up trial|BEHAVIORAL: Experimental: 40 minute down trial|BEHAVIORAL: Experimental: Two 20 minute up trials|BEHAVIORAL: Experimental: Two 20 min down trials|BEHAVIORAL: Active Comparator: Sedentary trial
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Iron Isomaltoside 1000 (Monofer®) in Non-Dialysis Dependent Chronic Kidney Disease and With Renal-Related Anaemia
Status: COMPLETED
Conditions: Iron Deficiency Anemia|Chronic Kidney Disease
Interventions: DRUG: Monofer|DRUG: Iron Sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Modified Esophagogastric Reconstruction Method After Laparoscopic Proximal Gastrectomy
Status: RECRUITING
Conditions: Proximal Gastric Adenocarcinoma|Adenocarcinoma of Esophagogastric Junction|Anastomosis
Interventions: PROCEDURE: "arch-bridge-type" esophagogastric reconstruction after proximal gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simultaneous Determination of Blood Pressure by Oscillometry and Photoplethysmography Compared to the Standard Inert Gas Rebreathing Technique
Status: UNKNOWN
Conditions: BLOOD PRESSURE
Interventions: OTHER: Détermination and comparison of blood pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Technology-Based Intervention to Promote Heart Health After Cardiac Rehab (Mobile4Heart)
Status: COMPLETED
Conditions: Ischemic Heart Disease|Unstable Angina|Systolic Heart Failure|Cardiovascular Diseases
Interventions: BEHAVIORAL: Movn Mobile App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy, Safety, Tolerability, Immunogenicity and Pharmacokinetic Evaluation of HYQVIA in Pediatric PIDD Subjects
Status: COMPLETED
Conditions: Primary Immunodeficiency Diseases (PID)
Interventions: BIOLOGICAL: HYQVIA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Study: Impact of Biomarker-Guided Dietary Supplementation on Quality-of-Life Measures in Subjects With Chronic Pain
Status: RECRUITING
Conditions: Chronic Pain
Interventions: DIETARY_SUPPLEMENT: Inflammation Support Formula|DIETARY_SUPPLEMENT: Nerve Health Formula|DIETARY_SUPPLEMENT: Redox Support Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Metformin Therapy in Non-diabetic AAA Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Abdominal Aortic Aneurysm
Interventions: DRUG: Metformin Glucophage 500mg (IR) tablets M90|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Investigate the Safety, Tolerance, Food Effect, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of Extended Release Formulations of Centanafadine (CTN) in Young Healthy Subjects
Status: TERMINATED
Conditions: Adult Attention-deficit Hyperactivity Disorder (ADHD)
Interventions: DRUG: CTN SR1|DRUG: CTN XR1|DRUG: CTN XR2|DRUG: CTN XR3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Low Dose Sugammadex in Reversal of NMB in Laparoscopic Barbaric Surgery
Status: COMPLETED
Conditions: Bariatric Patients
Interventions: DRUG: sugammadex reversal of neuromuscular blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: High-strength Glass-ionomer Dental Restorations
Status: COMPLETED
Conditions: Dental Caries
Interventions: DEVICE: Chemfil ROCK Glassionomer restoration|DEVICE: Fuji IX GP Extra Glassionomer restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of the ADL-Glittre Test in the Pre and Postoperative Period of Patients With Lung Cancer
Status: ENROLLING_BY_INVITATION
Conditions: Lung Cancer, Nonsmall Cell|Quality of Life|Physical Disability|Surgery
Interventions: OTHER: ADL-Glittre Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomised Control Trial for Improving Functional Outcome From Stroke in End Stage Renal Disease Patients
Status: COMPLETED
Conditions: Stroke|End Stage Renal Disease
Interventions: DEVICE: Computer-based target pursuit task (created using E-Prime software) and visual-feedback handgrip force transducer (CurrentDesigns 2012).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study of MK0633 in Patients With Chronic Obstructive Pulmonary Disease (COPD)(0633-009)(COMPLETED)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: MK633|DRUG: Comparator: Placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy and Safety of QL0911 in the Prevention of Chemotherapy- Induced Thrombocytopenia
Status: UNKNOWN
Conditions: Chemotherapy-induced Thrombocytopenia
Interventions: DRUG: QL0911|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: HCT With PTCy in Higher-risk MDS
Status: ACTIVE_NOT_RECRUITING
Conditions: Patients With MDS, Acute Myeloid Leukemia (AML) Evolving From MDS, and Chronic Myelomonocytic Leukemia (CMML)
Interventions: DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Recognition and Response to Increases in Surgical Site Infections Using Optimized Statistical Process Control Charts: The Early 2RIS Study
Status: COMPLETED
Conditions: Infection Control|Surgical Site Infection
Interventions: OTHER: Intervention Cluster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase Ib Study of HS-10352 Plus Fulvestrant in Patients With Advanced Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: HS-10352 combined with fulvestrant (Stage 1)|DRUG: HS-10352 combined with fulvestrant (Stage 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diet and Meal Timing in Patients With Non-Alcoholic Fatty Liver Disease: A Pilot Study
Status: RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: BEHAVIORAL: TRE plus SOC|BEHAVIORAL: SOC|BEHAVIORAL: TRE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of Metformin Hydrochloride Liquid 500mg/ 5 mL Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: metformin hydrochloride liquid 500 mg per 5 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy and Safety of Terlipressin With Albumin Versus Midodrine With Albumin Versus Albumin Alone in Prevention of Paracentesis Induced Circulatory Dysfunction in Cirrhosis
Status: COMPLETED
Conditions: Cirrhosis
Interventions: DRUG: Terlipressin|DRUG: Midodrine|DRUG: Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dialogue to Empower Traditional and Faith Healers to Deliver mhGAP-IG Adapted Psychosocial Interventions in Kenya
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: BEHAVIORAL: mhGAP-IG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single- and Multiple-Ascending Doses and Food Effect of BGB-45035
Status: RECRUITING
Conditions: Healthy Participants|Healthy Subjects|Healthy Volunteers|Autoimmune Diseases|Healthy Adult Participants
Interventions: DRUG: BGB-45035|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effect of MK0633 in Patients With Chronic Asthma (0633-007)
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: MK0633|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Ischemic Post-stroke Depression
Status: COMPLETED
Conditions: Post-stroke Depression
Interventions: DEVICE: acupuncture|DRUG: placebo|DEVICE: sham-acupoint acupuncture|DRUG: Fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Combining Behavioral and Pharmacologic Therapy for Complex Insomnia in Veterans With PTSD
Status: ACTIVE_NOT_RECRUITING
Conditions: Complex Insomnia
Interventions: DRUG: eszopiclone|BEHAVIORAL: Brief behavioral therapy for insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjustable Fortification of Human Milk Fed to Chinese Preterm Infants
Status: COMPLETED
Conditions: Infant, Premature, Diseases
Interventions: DIETARY_SUPPLEMENT: human milk fortifier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Risk Factor Strategy vs a Guideline-Based Approach in Achieving Blood Pressure and Lipid Goals in Hypertensives at Extra Risk
Status: COMPLETED
Conditions: Dyslipidemia|Hypertension
Interventions: DRUG: Amlodipine besylate|DRUG: Amlodipine besylate/atorvastatin calcium single pill combination|DRUG: Amlodipine besylate|DRUG: Amlodipine besylate/atorvastatin calcium single pill combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT