pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Lutein and Zeaxanthin Supplementation on Early Age-related Macular Degeneration
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: DIETARY_SUPPLEMENT: placebo|DIETARY_SUPPLEMENT: low lutein|DIETARY_SUPPLEMENT: high lutein|DIETARY_SUPPLEMENT: lutein plus zeaxanthin|DIETARY_SUPPLEMENT: high zeaxanthin|DIETARY_SUPPLEMENT: zeaxanthin plus lutein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Theta Burst Stimulation to Improve Inhibitory Motor Physiology in Tourette Syndrome
Status: RECRUITING
Conditions: Tourette Syndrome|Tourette Syndrome in Children|Tourette Syndrome in Adolescence|Tourette Syndrome, Modifier of
Interventions: DEVICE: iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect and Mechanism of Bronchoscopic Lung Volume Reduction by Endobronchial Valve in Korean Emphysema Patients
Status: COMPLETED
Conditions: Pulmonary Emphysema
Interventions: DEVICE: Endobronchial valve
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glenohumeral Re-centering During Closed Kinetic Chain for Shoulder Physiotherapy. A Prospective and Randomized Study.
Status: TERMINATED
Conditions: Subacromial Impingement of the Shoulder
Interventions: OTHER: Group C: physiotherapy protocol with Conventional physiotherapy.|OTHER: Group S: physiotherapy protocol with Dynamic Humeral Centering.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hepatic Resection for Metastatic Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Neoplasms|Neoplasm Metastasis|Liver Metastases
Interventions: PROCEDURE: Hepatic Resection or Ablation with Pancreaticoduodenectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Influence of Preprandial Metformin Administration on Carbohydrate Absorption
Status: NOT_YET_RECRUITING
Conditions: Impaired Glucose Tolerance|Type2 Diabetes
Interventions: OTHER: Oral glucose tolerance test (OGTT) with or without metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Microbiome of Sputum, Urine and Feces in Healthy Persons and Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: UNKNOWN
Conditions: Pulmonary Disease, Chronic Obstructive|Emphysema or COPD|Microbiota
Interventions: DIAGNOSTIC_TEST: obtain samples from sputum, feces and urine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Flushing Reduction Associated With Nitrates
Status: COMPLETED
Conditions: Menopausal Hot Flashes
Interventions: DRUG: transdermal nitroglycerin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of JHG002 for Chronic Temporomandibular Joint Dysfunction: A Multicenter Randomized Controlled Trial
Status: COMPLETED
Conditions: Temporomandibular Disorder
Interventions: OTHER: hominis placental pharmacopuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SMAD2, SMAD3 AND TGF-β GENE EXPRESSION IN URGE URINARY INCONTINENCE
Status: COMPLETED
Conditions: SMAD2|SMAD3|TGF-β|Pelvic Organ Prolapse|Urge Urinary Incontinence
Interventions: GENETIC: SMAD2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nutrition Education for Cardiovascular Disease Prevention in Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: BEHAVIORAL: Control|BEHAVIORAL: Eat Smart, Live Better
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Education With Image Illustrations Enhances Effect of Tetracaine Mucilage in Alleviating Postoperative CRBD
Status: UNKNOWN
Conditions: Catheter Site Discomfort
Interventions: OTHER: Preoperative education with image illustrations and/or local tetracaine mucilage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib in Treating Patients With Regional or Metastatic Cancer of the Urothelium
Status: TERMINATED
Conditions: Adenocarcinoma of the Bladder|Distal Urethral Cancer|Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter|Proximal Urethral Cancer|Recurrent Bladder Cancer|Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter|Recurrent Urethral Cancer|Regional Transitional Cell Cancer of the Renal Pelvis and Ureter|Squamous Cell Carcinoma of the Bladder|Stage III Bladder Cancer|Stage IV Bladder Cancer|Transitional Cell Carcinoma of the Bladder|Urethral Cancer Associated With Invasive Bladder Cancer
Interventions: DRUG: sorafenib tosylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fumaric Acid Ester-PUVA Therapy Versus Acitretin -PUVA Therapy in Pustular Palmoplantar Psoriasis
Status: UNKNOWN
Conditions: Pustular Palmoplantar Psoriasis
Interventions: RADIATION: 8-methoxypsoralen or 5- methoxypsoralen|RADIATION: 8-methoxypsoralen or 5methoxypsoralen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Safety and Efficacy of COMBIVENT HFA to COMBIVENT (CFC) in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: TERMINATED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: COMBIVENT HFA|DRUG: Placebo HFA|DRUG: COMBIVENT CFC|DRUG: Placebo CFC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Equivalence and Safety Study of RPH-001 and Avastin®
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: RPH-001|BIOLOGICAL: Avastin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Japanese Men to Test How Well Different Doses of BI 3006337 Are Tolerated
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: DRUG: BI 3006337|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Infusion in Hypospadias Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Dexmedetomidine and Fentanyl|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety, Reactogenicity, and Immunogenicity of Cytomegalovirus Vaccines mRNA-1647 and mRNA-1443 in Healthy Adults
Status: COMPLETED
Conditions: Cytomegalovirus Infection
Interventions: BIOLOGICAL: mRNA-1647|BIOLOGICAL: mRNA-1443|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Mobilizing Community Systems to Engage Families in Early Autism Spectrum Disorder (ASD) Detection & Services
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Autism Navigator Enhanced Practice|BEHAVIORAL: Family Engagement plus Autism Navigator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ph II Concurrent Chemo t/Docetaxel/Carboplatin/Radio Therapy-consolidation t/Locally Adv Inoperable Non-Small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: Carboplatin|DRUG: Docetaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects -2
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: BIOLOGICAL: Evolocumab|DRUG: Placebo to Evolocumab|DRUG: Ezetimibe|DRUG: Placebo to Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ADL- Training for Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: ADL training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Zidovudine Plus Interleukin-2 in HIV-Infected Patients Who Have No Symptoms of Infection But Who Have Tender Lymph Nodes
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Approach Modification for Total Knee Arthroplasty in Morbidly Obese Patients
Status: RECRUITING
Conditions: Arthropathy|Incision, Surgical|Obesity, Morbid
Interventions: PROCEDURE: Small curved incision with apex lateral
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Responses to Fluzone® in Infants ≥ 6 Months of Age Who Did or Did Not Receive Fluzone® at 2 Months of Age
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza Virus Vaccine|BIOLOGICAL: Influenza Virus Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Propensity to Develop Plasticity in the Parieto-Motor Networks in Dystonia From the Perspective of Abnormal High-Order Motor Processing
Status: COMPLETED
Conditions: Writer's Cramp|Healthy Volunteers|Cervical Dystonia
Interventions: DEVICE: TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: RCT GBR One Stages Comparing A-Oss and Autogenous Bone Versus A-Oss and LCR-A
Status: NOT_YET_RECRUITING
Conditions: Guided Bone Regeneration|Dental Implant
Interventions: PROCEDURE: A-oss and autogenous bone|PROCEDURE: A-oss an LCR-A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Pharmacokinetics of an Oral Contraceptive (Brevicon) When Co-administered With Albiglutide .
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BIOLOGICAL: albiglutide|DRUG: Oral contraceptive (Brevicon)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Platelet-Rich Plasma Injection Versus Hydrodissection in the Treatment of Carpal Tunnel Syndrome
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: ultrasound guided PRP injection|OTHER: ultrasound guided hydrodissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: In Utero Fetoscopic Repair Program for Sacral Myelomeningoceles and Mye-LDM
Status: UNKNOWN
Conditions: Sacral Myelomeningocele|Neural Tube Defects|Spina Bifida
Interventions: PROCEDURE: Fetoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caring for Providers to Improve Patient Experience (CPIPE) Trial
Status: ENROLLING_BY_INVITATION
Conditions: Stress, Psychological|Maternal Health|Healthcare Provider|Adverse Outcomes|Stress, Emotional|Mental Health Issue|Burnout|Burnout, Psychological|Discrimination, Social
Interventions: BEHAVIORAL: CPIPE Training|BEHAVIORAL: Peer support groups|BEHAVIORAL: Mentorship|BEHAVIORAL: Leadership engagement|BEHAVIORAL: Embedded champions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Recombinant Factor VIIa BI (rFVIIa BI) Treatment of Acute Bleeding Episodes Per an On-demand Regimen
Status: COMPLETED
Conditions: Hemophilia A|Hemophilia B
Interventions: BIOLOGICAL: Recombinant Factor VIIa BI (rFVIIa BI)|BIOLOGICAL: Recombinant Factor VIIa BI (rFVIIa BI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VIVID - Valvular and Ventricular Improvement Via iCoapsys Delivery - Feasibility Study
Status: UNKNOWN
Conditions: Mitral Valve Regurgitation|Left Ventricular Dysfunction|Heart Failure|Mitral Insufficiency|Mitral Incompetence|Ischemic Heart Disease
Interventions: DEVICE: Percutaneous mitral valve repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epirubicin, Oxaliplatin and Fluorouracil (EOF) in Cancer of the Esophagus, Gastroesophageal Junction, or Stomach
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: cisplatin|DRUG: epirubicin hydrochloride|DRUG: fluorouracil|DRUG: oxaliplatin|PROCEDURE: adjuvant therapy|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety and Tolerability of EO2002
Status: RECRUITING
Conditions: Cataract|Endothelial Cell Loss, Corneal
Interventions: BIOLOGICAL: EO2002|OTHER: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of 3 Different Doses of Long Acting Factor VII in Haemophilia A or B Patients With Inhibitors
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A With Inhibitors|Haemophilia B With Inhibitors
Interventions: DRUG: activated recombinant human factor VII, long acting|DRUG: activated recombinant human factor VII, long acting|DRUG: activated recombinant human factor VII, long acting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Anti-Tumor Activity and Safety of Odronextamab in Adult Patients With B-cell Non-Hodgkin Lymphoma Who Have Been Previously Treated With Other Cancer Therapies
Status: RECRUITING
Conditions: B-cell Non-Hodgkin Lymphoma (B-NHL)
Interventions: DRUG: Odronextamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Homeopathic Preparation Plumbum Metallicum for Lead Poisoning
Status: COMPLETED
Conditions: Lead Poisoning
Interventions: DRUG: Homeopathic medication Plumbum metallicum|OTHER: Hydroalcoholic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of LopiGLIK® on Cardiovascular Risk
Status: COMPLETED
Conditions: Cardiovascular Risk Factors
Interventions: OTHER: Placebo|OTHER: Prescribed Diet|DIETARY_SUPPLEMENT: LopiGLIK®|DIETARY_SUPPLEMENT: Armolipid Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Biomarker Study in Pancreatic Neuroendocrine Tumours
Status: UNKNOWN
Conditions: Neuroendocrine Tumors
Interventions: PROCEDURE: Core Needle Biopsy|RADIATION: Computed Tomography|RADIATION: 18F-FDG-PET|PROCEDURE: Phlebotomy|GENETIC: Molecular genetic analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Safety and Tolerability of OraVescent Fentanyl for Opioid Tolerant Patients With Noncancer Related Breakthrough Pain
Status: COMPLETED
Conditions: Low Back Pain|Migraine|Diabetic Neuropathies|Osteoarthritis
Interventions: DRUG: OraVescent Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Systemic Metal Ion Concentration Following a Ceramic-on-metal Total Hip Arthroplasty
Status: WITHDRAWN
Conditions: Hip Replacement|Hip Implant|Total Hip Arthroplasty|Orthopaedic Surgery
Interventions: BIOLOGICAL: Blood draw|RADIATION: X-Ray of Hip
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neoadjuvant Chemotherapy for Operable Premenopausal Breast Cancer Patients
Status: UNKNOWN
Conditions: Breast Cancer Nos Premenopausal
Interventions: DRUG: Docetaxel|DRUG: epirubicin|DRUG: cyclophosphamide|PROCEDURE: Modified radical mastectomy or breast-conserving Surgery|DRUG: Docetaxel (post-operative)|DRUG: Epirubicin (post-operative)|DRUG: Cyclophosphamide (post-operative)|RADIATION: Radiation therapy|DRUG: Herceptin （post-operative)|DRUG: Tamoxifen (post-operative)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Inorganic Nitrate and Intensity of Exercise on Cardiovascular Health in Post-Menopausal Females
Status: COMPLETED
Conditions: Vascular Dilation|Arterial Stiffness
Interventions: DRUG: BEET IT - Concentrate Beet root juice|DRUG: BEET IT - Concentrate Beet root juice (nitrate depleted)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Testing the Utilization of a Mobile Health App for Patients Undergoing Cystectomy Surgery for Bladder Cancer
Status: COMPLETED
Conditions: Invasive Bladder Cancer
Interventions: OTHER: Mobile Health app tool - Twistle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Immunization of Patients With Metastatic Melanoma Using the GP100 Peptide Preceded by an Endoplasmic Reticulum Insertion Signal Sequence
Status: COMPLETED
Conditions: Melanoma|Neoplasm Metastasis
Interventions: DRUG: GP100 peptide|DRUG: IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: SBRT, Chemotherapy, and AK104 Neoadjuvant Therapy for Triple-negative Breast Cancer (TNBC)
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Cadonilimab (AK104)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind, Sham-controlled Pilot Study to Evaluate the Treatment Efficacy of Magnetic EEG/ECG-Guided Resonance Therapy (MeRT) in College Students With ADHD
Status: COMPLETED
Conditions: ADHD
Interventions: DEVICE: Active MeRT Treatment|DEVICE: Sham MeRT Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Primary Surgery Followed Selective Radiochemotherapy for Rectal Cancer With MRI Negative CRM
Status: SUSPENDED
Conditions: Colorectal Neoplasm|Effects of Radiation Therapy|Effects of Chemotherapy|Surgery
Interventions: PROCEDURE: Rectectomy|RADIATION: Radiotherapy|DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Positive Airway Pressure Therapy on Hospitalization and Mortality in SDB Patients With Comorbid Chronic Obstructive Pulmonary Disease (COPD) or/and Heart Failure (HF)
Status: COMPLETED
Conditions: Sleep-Disordered Breathing|Pulmonary Disease, Chronic Obstructive|Heart Failure
Interventions: PROCEDURE: polygraphy or polysomnography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TISSIUM™ Atraumatic Hernia Repair System (TAHRS) Pilot Study
Status: RECRUITING
Conditions: Hernia
Interventions: DEVICE: TISSIUM™ Atraumatic Hernia Repair System (TAHRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mindfulness Compassionate Living Practice on Hemodialysis Patients
Status: NOT_YET_RECRUITING
Conditions: Hemodialysis Patients
Interventions: BEHAVIORAL: 1: How We Evolved - Threat, Impulse, and Soothing Systems|BEHAVIORAL: Session 2: Threat and Self-Compassion|BEHAVIORAL: Session 3: Unraveling the Knots of Desire and Patterns Agenda|BEHAVIORAL: Session 4: Internalizing compassion|BEHAVIORAL: Session 5: Me and others - Expanding the circle|BEHAVIORAL: Session 6: Growing happiness|BEHAVIORAL: Session 7: Weaving Wisdom and Compassion into Daily Life|BEHAVIORAL: Session 8: Living with the Heart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Controlled, 12-Week Study of Albuterol HFA Versus the Active Control, Proventil(R)-HFA in Asthmatic Patients
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: albuterol HFA (Armstrong's)|DRUG: albuterol HFA (Proventil HFA)|DRUG: HFA placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Immunogenicity, and Safety of the Inactivated COVID-19 Vaccine (TURKOVAC) Versus the CoronaVac Vaccine
Status: COMPLETED
Conditions: Covid19
Interventions: BIOLOGICAL: TURCOVAC|BIOLOGICAL: CoronaVac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: "Phase III Randomized Trial Comparing D2 vs D3 Lymphadenectomy With Gastric Cancer Following Neoadjuvant Chemotherapy
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: PROCEDURE: D3 Lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of TOP1630 for Dry Eye Syndrome
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DRUG: TOP1630 Ophthalmic Solution|DRUG: Placebo to TOP1630 Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Motion and Comfort for Thoracolumbosacral Orthoses - Group 2
Status: COMPLETED
Conditions: Back Injuries
Interventions: DEVICE: DJO 456|DEVICE: Aspen 456|DEVICE: DJO 464|DEVICE: Aspen 464
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Testing Interventions to Reduce Alcohol Consumption Among Outpatients in a Dental Setting
Status: TERMINATED
Conditions: Alcohol Addiction|Mouth Diseases
Interventions: DEVICE: Drinksmeter|BEHAVIORAL: Brief Advice of Alcohol Use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sipuleucel-T Combined With Bipolar Androgen Therapy in Men With mCRPC
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Testosterone Cypionate|DRUG: Sipuleucel-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Rebif, Copaxone, and Tysabri for Active Multiple Sclerosis
Status: TERMINATED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: BG00002 (natalizumab)|DRUG: interferon beta-1a|DRUG: glatiramer acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study of SHR8554 Injection for the Treatment of Pain After Orthopedic Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: SHR8554 Injection|DRUG: SHR8554 Injection|DRUG: Saline Solution|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Metastatic Solid Tumors
Status: COMPLETED
Conditions: Malignant Solid Tumour|Breast Cancer|Malignant Tumor of Colon|GIST|Ovarian Cancer
Interventions: BIOLOGICAL: HER-2 vaccine|BIOLOGICAL: Extension HER-2 vaccine trial at OBD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Aprepitant in Addition to Ondansetron in the Prevention of Nausea and Vomiting Caused by Upper Abdominal Radiotherapy
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: DRUG: aprepitant|DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1 Antibody and Radiotherapy for Recurrent Cervical Cancer
Status: UNKNOWN
Conditions: Immune Checkpoint Inhibitors|Anti-programmed Death-1 Antibody|Radiotherapy|Recurrent Cervical Carcinoma|Metastatic Cervical Carcinoma|Persistent Advanced Cervical Carcinoma|Objective Remission Rate|Progression-free Survival|Overall Survival|Severe Adverse Events
Interventions: COMBINATION_PRODUCT: Radiotherapy for targeted lesions and PD-1 antibody
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Safety and Preliminary Efficacy of AAV-DC-CTL Treatment in Stage IV Gastric Cancer
Status: UNKNOWN
Conditions: Stage IV Gastric Cancer
Interventions: BIOLOGICAL: Antigen-specific cytotoxic T lymphocytes induced by dendritic cells infected by recombinant adeno-associated virus with CEA gene
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Demonstrate Equivalent Efficacy and to Compare Safety of Biosimilar Adalimumab (GP2017) and Humira
Status: COMPLETED
Conditions: Plaque Type Psoriasis
Interventions: DRUG: GP2017 Adalimumab|DRUG: Humira ® Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Safety of the 360-degree Turn Test Delivered Via Telehealth
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: DIAGNOSTIC_TEST: 360-degree Turn Test|OTHER: Expanded Disability Status Scale|OTHER: Perceived Exertion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Trimetazidine in Diabetic Patients
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Diabetic Cardiomyopathies
Interventions: DRUG: Trimetazidine Dihydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of TaiHao Breast Ultrasound Diagnosis Software
Status: COMPLETED
Conditions: Breast Cancer|Breast Diseases
Interventions: DIAGNOSTIC_TEST: Reader Group X - Session 1|DIAGNOSTIC_TEST: Reader Group Y - Session 1|DIAGNOSTIC_TEST: Reader Group X - Session 2|DIAGNOSTIC_TEST: Reader Group Y - Session 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of 2-Week Continuous Glucose Monitoring on Glycemic Management in Patients New-to-Insulin on Hospital Discharge
Status: NOT_YET_RECRUITING
Conditions: Diabetes
Interventions: DEVICE: Continuous Glucose Monitor|DEVICE: Blood Glucose Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Aim of This Study is to Demonstrat That Vacuum-assisted Closure Versus Conventional Wound Closure Enables to Diminish Local Complications After Lymph Node Dissection in Patients With Metastatic Skin Tumors
Status: UNKNOWN
Conditions: Melanoma|Skin Cancer|Epidermoid Carcinoma|Neuroendocrine Carcinoma|Lymph Node Metastases
Interventions: DEVICE: PREVENA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combined Chemoembolization and Systemic Hyperthermia for Unresectable Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: TACE with Hyperthermia Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Trigeminal Neurostimulation on Heart Rate Variability: Comparing Tragus and Tongue Stimulation.
Status: COMPLETED
Conditions: Arousal, Confusional
Interventions: DEVICE: device that stimulates the dorsal surface of the tongue|DEVICE: device that stimulates the tragus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Probiotics on Immune Function and Intestinal Microbiota in Astronauts Under Closed Microgravity Environment
Status: UNKNOWN
Conditions: Immune Function and Intestinal Microbiota
Interventions: DIETARY_SUPPLEMENT: Probiotic capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of a Combination of a Plant Extract and a Probiotic on Glucidic Metabolism in Women With PCOS and High Insulin Levels
Status: UNKNOWN
Conditions: Polycystic Ovarian Syndrome|Insulin Resistance
Interventions: COMBINATION_PRODUCT: Combination of a plant extract (BSL_EP044) and Lactobacillus BSL_PS6|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomised Trial of Structured Treatment Interruption of HAART in HIV-Infected Adults in Abidjan (ANRS 1269 TRIVACAN)
Status: COMPLETED
Conditions: HIV Infections
Interventions: PROCEDURE: Structured Treatment Interruption|DRUG: Zidovudine (ZDV)|DRUG: Lamivudine (3TC)|DRUG: Efavirenz (EFV)|DRUG: Ritonavir (NRV)|DRUG: Indinavir (IDV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Evaluating Two Treatment Protocols for Immunosuppressive Drugs. Looking at 3-year Incidence of CLAD.
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Transplantation|Allografts
Interventions: DRUG: Cyclosporine|DRUG: Mycophenolate mofetil (MMF)|DRUG: Rabbit Anti thymocyte globulin|DRUG: Corticosteroids|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Saroglitazar Magnesium for the Treatment of Nonalcoholic Steatohepatitis With Fibrosis
Status: RECRUITING
Conditions: Nonalcoholic Steatohepatitis|Fibrosis
Interventions: DRUG: Saroglitazar Magnesium 2 mg|DRUG: Saroglitazar Magnesium 4 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aquatic Sequential Preparatory Approach and Severe Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury|Severe Traumatic Brain Injury
Interventions: OTHER: Aquatic Training|OTHER: Conventional Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Product Properties of Individualized 3D-compression Garments to Treat Scars
Status: COMPLETED
Conditions: Burn Scar
Interventions: DEVICE: Compression garment (manual)|DEVICE: Compression garment (scan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Telemedicine vs. Face-to-Face Cancer Genetic Counseling
Status: COMPLETED
Conditions: Hereditary Breast and Ovarian Cancer Syndrome|Lynch Syndrome
Interventions: OTHER: Telemedicine|OTHER: Face-to-Face
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis: A Pilot Feasibility Study
Status: COMPLETED
Conditions: Shock, Septic
Interventions: DRUG: Lactated Ringer|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Supplementing Different Solutions on Firefighters' Simulated Fire Rescue Training
Status: COMPLETED
Conditions: Injury of Multiple Muscles and Tendons at Lower Leg Level
Interventions: DIETARY_SUPPLEMENT: energy drink
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy Evaluation of IM19 Cells
Status: UNKNOWN
Conditions: Hematological Malignancies
Interventions: BIOLOGICAL: IM19 CAR-T|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Descriptive Study of Receptive Fields in Lower Limb Amputees
Status: UNKNOWN
Conditions: Lower Limb Amputation Below Knee (Injury)
Interventions: DEVICE: Phantom Stimulator, Cort X Sensorics, Spaichingen, Germany
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Efficacy of Trapeziectomy Versus Sham Surgery in the Treatment of Osteoarthritis at the Base of the Thumb
Status: RECRUITING
Conditions: Thumb Osteoarthritis
Interventions: PROCEDURE: Trapeziectomy|PROCEDURE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Study on the Treatment of Sacral Canal Cysts With Sacral Canal Reinforcement
Status: UNKNOWN
Conditions: Tarlov Cysts
Interventions: PROCEDURE: entraped treatment|PROCEDURE: plasty treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men and Women to Test How Well Different Doses of BI 1323495 Are Tolerated
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1323495|DRUG: Placebo|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aliskiren HCTZ Compared to Amlodipine in Patients With Stage 2 Systolic Hypertension and Diabetes Mellitus
Status: COMPLETED
Conditions: Hypertension|Diabetes Mellitus
Interventions: DRUG: Amlodipine|DRUG: Hydrochlorothiazide (HCTZ)|DRUG: Aliskiren
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Effects of Inspiratory Muscle Training in Chronic Venous Insufficiency
Status: RECRUITING
Conditions: Chronic Venous Insufficiency
Interventions: OTHER: Training group: Inspiratory muscle training|OTHER: Control group: Thoracic expansion exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Food Supplementation With Eufortyn Colesterolo Plus for LDL Modulation in Subjects With Polygenic Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Eufortyn Colesterolo Plus|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pilates Exercises and Diaphragm Manual Therapy Techniques in Rotator Cuff Tendinopathy
Status: RECRUITING
Conditions: Shoulder Tendinitis|Shoulder Rotator Cuff Tendinopathy
Interventions: OTHER: pilates exercise and diaphragm manual technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pregabalin on Post-cesarean Pain
Status: COMPLETED
Conditions: Uncomplicated Singleton Pregnancies
Interventions: DRUG: Placebo|DRUG: Pregabalin 300 mg group|DRUG: Pregabalin 150 mg group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standard Medical Care or Urgent Chest X-ray in Diagnosing Lung Cancer in Smokers With Chest Symptoms Who Are Older Than 60 Years
Status: UNKNOWN
Conditions: Lung Cancer|Tobacco Use Disorder
Interventions: OTHER: caregiver-related intervention or procedure|OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment|PROCEDURE: radiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of AXT-1003 in Adult Subjects With Relapsed/Refractory Non-Hodgkin Lymphomas
Status: TERMINATED
Conditions: Relapsed or Refractory Non-Hodgkin's Lymphoma
Interventions: DRUG: AXT-1003
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Telehealth Advance Care Planning Intervention
Status: RECRUITING
Conditions: Myeloid Malignancy|Acute Myeloid Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasm|Myelofibrosis
Interventions: BEHAVIORAL: Telehealth Serious Illness Care Program|OTHER: Education Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate Safety and Efficacy of PreCrea® on Subjects With Higher Than Normal Blood Sugar Levels
Status: COMPLETED
Conditions: Diabetes Mellitus|Pre-Diabetes|Hyperglycemia|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Study dietary supplement (PreCrea 600 mg capsules)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Survival Analysis After Neoadjuvant Therapy in Patients With Resectable Pancreatic Cancer and Risk Factors
Status: RECRUITING
Conditions: Pancreatic Adenocarcinoma|Pancreatic Cancer Resectable
Interventions: DRUG: Folfirinox and Stereotactic Body Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Nerve Stimulation and Cognitive Training to Improve Cognitive Performance in Healthy Older Adults
Status: RECRUITING
Conditions: Aging
Interventions: DEVICE: Transcutaneous vagal nerve stimulation (tVNS)|BEHAVIORAL: cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Postrual Reduction With Pillow in Osteoporotic Vertebral Fracture
Status: UNKNOWN
Conditions: Compression Fracture Spine|Osteoporosis Fracture
Interventions: OTHER: Pillow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Screening Strategy for Gastric Cancer Prevention
Status: NOT_YET_RECRUITING
Conditions: H. Pylori Infection
Interventions: DIAGNOSTIC_TEST: UBT|DIAGNOSTIC_TEST: HPSA|DIAGNOSTIC_TEST: UBT and HPSA|DIAGNOSTIC_TEST: Serology (two stage)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Quality of Telemedically Guided Prehospital Analgesia
Status: COMPLETED
Conditions: Analgesia|Prehospital|Telemedicine|Ambulance|Opioids|Teleconsultation|Tele-emergency Medical Services|Adverse Events|City of Aachen|Prehospital Emergency Medical Service Physician
Interventions: PROCEDURE: physician operated telemedical prehospital analgesia|PROCEDURE: prehospital analgesia by on-scene EMS physicians
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics of LEO 43204 Gel in Actinic Keratosis Administered Under Maximal Use Conditions
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: LEO 43204 gel 0.018%|DRUG: LEO 43204 gel 0.1%|DRUG: LEO 43204 gel 0.037%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Cinacalcet on Arterial Stiffness and Ventricular Function in Hemodialysis Patients
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Cinacalcet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Cost-efficacy of Sealing Moderate Caries Lesions in Occlusal Surfaces of Primary Molars
Status: UNKNOWN
Conditions: Dental Caries
Interventions: PROCEDURE: Ionomer Restoration (control)|PROCEDURE: Ionomer Sealant (test)|PROCEDURE: Oral hygiene orientation and professional fluoride application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Adjunctive Role of Vitamin C on Pigment Recurrence (Randomized Clinical and Histological Trial)
Status: RECRUITING
Conditions: Gingival Pigmentation
Interventions: PROCEDURE: Injectable applied vitamin C|PROCEDURE: Topical applied Vitamin C|PROCEDURE: Surgical depigmentation only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive Subjects
Status: COMPLETED
Conditions: Depression|HIV Infections|HIV-Associated Cognitive Motor Complex
Interventions: DRUG: 18F-FDOPA|DRUG: 11C-DASB
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study to Assess the Efficacy and Safety of Three Doses of Vildagliptin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Refractory Sever Systemic Scleroderma by Injection of Allogeneic Mesenchymal Stem Cells
Status: COMPLETED
Conditions: SYSTEMIC SCLERODERMA|ALLOGENEIC MESENCHYMAL STEM CELLS|ADULT
Interventions: BIOLOGICAL: INJECTION OF ALLOGENEIC MESENCHYMAL STEM CELLS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Delta-9 Tetrahydrocannabinol (THC) on Retention of Memory for Fear Extinction Learning in PTSD: R61 Study
Status: COMPLETED
Conditions: PostTraumatic Stress Disorder
Interventions: DRUG: Placebo Oral Capsule|DRUG: Dronabinol Cap 5 milligrams (MG)|DRUG: Dronabinol Cap 10 milligrams (MG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate Safety, Tolerability and Pharmacokinetics of GSK2269557 to Japanese Healthy Subjects
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK2269557 ELLIPTA DPI|DRUG: Placebo ELLIPTA DPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CD34+ Transplants for Leukemia and Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Leukemia, Myeloid, Acute|Leukemia, Lymphocytic, Acute
Interventions: RADIATION: Total Body Irradiation (TBI)|DRUG: Thiotepa|DRUG: Cyclophosphamide|DRUG: Busulfan|DRUG: Melphalan|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacodynamics of CYT013-IL1bQb in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: CYT013-IL1bQb|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of an Integrated Approach to Prevention and Early Intervention in the Elementary School Years
Status: COMPLETED
Conditions: Aggression
Interventions: BEHAVIORAL: PATHS to PAX|BEHAVIORAL: PATHS to PAX and the Incredible Years
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION