pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Identification of Biomarkers That Are Predictive of Early Ibrutinib Treatment Failure in High Risk TP53 Mutated Chronic Lymphocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Ibrutinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optimal Injection Interval for Intra-Detrusor Botulinum Toxin
Status: NOT_YET_RECRUITING
Conditions: Overactive Bladder|Urinary Urgency|Urinary Incontinence|Urge Urinary Incontinence
Interventions: BEHAVIORAL: Patient-directed follow up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Thoracic Epidural Analgesia for Thoracotomy on the Occurrence of AF
Status: UNKNOWN
Conditions: Posterolateral Thoracotomy|Lung Resection|Thoracic Epidural Analgesia|Sympathetic Outflow|Atrial Fibrillation
Interventions: OTHER: Thoracic Epidural Analgesia (TEA)|OTHER: TEA followed by Intravenous morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lapatinib or Trastuzumab Given Prior to Surgery With Chemotherapy in Patients With Early Breast Cancer
Status: WITHDRAWN
Conditions: Neoplasms, Breast
Interventions: DRUG: Lapatinib|DRUG: Trastuzumab|DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beta-Tricalcium Phosphate and Concentrated Growth Factors in Treatment of Intra-bony Defect Randomized Clinical Trial
Status: COMPLETED
Conditions: Chronic Periodontitis|Intrabony Periodontal Defect|Concentrated Growth Factors
Interventions: PROCEDURE: open flap debridement|OTHER: use of Biodegradable Gelatin Sponge loaded with Beta-tricalcium Phosphate plus concentrated growth factors|OTHER: use of Biodegradable Gelatin Sponge loaded with Beta-tricalcium Phosphate alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Influence of Co-ingestion of Alcohol on Hydrocodone Bitartrate Extended Release (HC-ER)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HC-ER + 40% Alcohol|DRUG: HC-ER + 20% Alcohol|DRUG: HC-ER + 0% Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Therapeutic Instrumental Music Performance With Sensory-Enhanced Motor Imagery in Chronic Post-Stroke Rehabilitation
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Therapeutic Instrumental Music Performance|BEHAVIORAL: Therapeutic Performance with Sensory-Enhanced Motor Imagery|BEHAVIORAL: Therapeutic Performance with Motor Imagery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bell's Palsy With a Duration of Greater Than 8 Weeks Treated With Multiwave Locked System Intervention
Status: COMPLETED
Conditions: Laser Treatment Relieve Symptoms of Chronic Bell's Palsy
Interventions: DEVICE: Multiwave Locked System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluticasone Versus Esomeprazole to Treat Eosinophilic Esophagitis
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: Swallowed fluticasone|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Quinvaxem for Vaccination Against Diphtheria, Pertussis, Tetanus, Hepatitis B and Diseases Caused by Haemophilus Influenzae Type B
Status: COMPLETED
Conditions: Diphtheria|Pertussis|Tetanus|Hepatitis B|Haemophilus Influenzae Infections
Interventions: BIOLOGICAL: Quinvaxem
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INdobufen Versus aSpirin in acUte Ischemic stRokE,INSURE
Status: COMPLETED
Conditions: Ischemic Stroke|Indobufen|Aspirin
Interventions: DRUG: Indobufen|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double-Blind Clinical Trial of Subthalamic Nucleus Deep Brain Stimulation in Early-Stage Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: active subthalamic nucleus deep brain stimulation plus optimal drug therapy|DEVICE: inactive subthalamic nucleus deep brain stimulation plus optimal drug therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Low-dose Naproxen in Cognitively Intact Persons at Risk of Alzheimer's Dementia
Status: COMPLETED
Conditions: Alzheimer Disease|Cognitive Decline Due to Alzheimer Disease|Mild Cognitive Impairment Due to Alzheimer Disease
Interventions: DRUG: Naproxen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Sublingual Fentanyl on Breathlessness in COPD
Status: UNKNOWN
Conditions: Copd
Interventions: DRUG: Fentanyl citrate solution sublingual|DRUG: Placebo oral liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Singing Groups for Seniors: Well-Being, Cognitive Function and Health
Status: COMPLETED
Conditions: Cognitive Function|Well-Being|Physical Function|Respiratory Function|Memory|Biomarker|Anxiety|Depression|Stress|Quality of Life|Loneliness|Social Identification|Blood Pressure|Blood Glucose|Cholesterol|C-reactive Protein|Erythrocyte Sedimentation Rate|Balance|Sleep|Pain Perception|Medication Compliance|Health Complaint, Subjective|Body Weight
Interventions: OTHER: Singing Group Intervention Program|OTHER: Alternative Social and Leisure Activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-Term Versus 6-Week Prednisone in The Treatment of Subacute Thyroiditis
Status: NOT_YET_RECRUITING
Conditions: Subacute Thyroiditis
Interventions: DRUG: 1-week predisone+1-week celecoxib|DRUG: 6-weeks predisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryoballoon Pulmonary Vein Isolation vs. Radiofrequency Pulmonary Vein Isolation With Additional Right Atrial Linear Ablation for Paroxysmal Atrial Fibrillation: Prospective Randomized Trial (CRAPAF Trial)
Status: UNKNOWN
Conditions: Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: Cryoballoon Pulmonary Vein isolation|PROCEDURE: Radiofrequency Pulmonary Vein isolation and Additional Right Atrial linear ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of TLR4 Inhibition in Obese and Type 2 Diabetic Subjects
Status: TERMINATED
Conditions: Insulin Sensitivity
Interventions: DRUG: Eritoran|DRUG: D5W
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Manual Versus Stapled Side to Side Ileocolic Anastomosis in Crohn's Disease
Status: RECRUITING
Conditions: Crohn Disease|IBD|Ileocolitis|Crohn's Ileocolitis
Interventions: PROCEDURE: Handsewn anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single-dose Pharmacokinetics of Oral Nicotine Replacement Products
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: DRUG: Nicotine|DRUG: Nicotine Gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exogenous Ketones and Behavior
Status: RECRUITING
Conditions: Behavior
Interventions: DIETARY_SUPPLEMENT: ketone ester|DIETARY_SUPPLEMENT: dextrose (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of MA-0217 (ASP1128) in Healthy Adult Subjects and Healthy Elderly Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ASP1128|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of a 7.5% Icodextrin Peritoneal Dialysis Solution in Once-Daily Long Dwell Exchange
Status: COMPLETED
Conditions: Chronic Kidney Disease|Peritoneal Dialysis
Interventions: DRUG: Icodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Tissue Flossing Technique for Bicipital Tendinitis
Status: COMPLETED
Conditions: Bicipital Tendinitis
Interventions: OTHER: Tissue Flossing Technique|OTHER: Static Stretching Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Docetaxel in Treating Patients With Inoperable Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: docetaxel|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Smoking Cessation on Clinical and Microbiological Outcomes of the Non-surgical Periodontal Therapy
Status: COMPLETED
Conditions: Periodontitis
Interventions: BEHAVIORAL: Smoking cessation counseling|PROCEDURE: Non-surgical periodontal therapy|DRUG: Nicotine replacement therapy|DRUG: bupropion hydrochloride|DRUG: Varenicline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Muscle Training Prior to Conventional and Minimal Invasive Heart Surgery
Status: WITHDRAWN
Conditions: Coronary Artery Bypass Graft Surgery|Valve Replacement|Post-Op Complications|Physiotherapy
Interventions: DEVICE: Inspiratory muscle training (IMT) using an IMT Threshold device (Philips)|OTHER: Standard physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Temsirolimus and Bevacizumab in Recurrent Glioblastoma Multiforme
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Temsirolimus|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of TAK-379 in Adult Subjects With Type 2 Diabetes Mellitus
Status: TERMINATED
Conditions: Diabetes Mellitus
Interventions: DRUG: TAK-379|DRUG: TAK-379|DRUG: TAK-379|DRUG: Pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin in the Recipient's Kidney Graft From a Living Donor
Status: COMPLETED
Conditions: Renal Insufficiency
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: WIreless Monitoring and Financial Incentives for Uncontrolled HYpertension (WIFHY) Study
Status: TERMINATED
Conditions: Hypertension
Interventions: OTHER: Usual Care|OTHER: Wireless HBPM System|BEHAVIORAL: BP Monitoring Incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Reducing Opioid Use and Misuse After Wisdom Molar Extractions
Status: NOT_YET_RECRUITING
Conditions: Pain, Postoperative
Interventions: DRUG: Twin block|DEVICE: iPill dispenser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of Allogeneic Haematopoietic Stem Cell Transplantation With FBM Conditioning for MDS
Status: RECRUITING
Conditions: Myelodysplastic Syndrome With Excess Blasts-1|Myelodysplastic Syndrome With Excess Blasts-2|Myelodysplastic Syndromes
Interventions: DRUG: Fludarabine, Busulfan and Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interpretation of Health News Items Reporting Results of Phase I/II (Non-randomized) Trials With or Without Spin by French-speaking Patients
Status: WITHDRAWN
Conditions: The Study Focus on no Specific Condition
Interventions: OTHER: News items with spin|OTHER: News items without spin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Safety Profile of Applied 100% Manuka Honey in Tympanoplasty
Status: COMPLETED
Conditions: Chronic Suppurative Otitis Media|Tympanic Membrane; Wound
Interventions: DRUG: Manukamed - Manukapli 100% sterile honey wound dressing - Premium medical grade 16+ Leptospermum Scoparium New Zealand honey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Pinhole Glasses on Vestibular Electrical Stimulation
Status: NOT_YET_RECRUITING
Conditions: Vertigo, Peripheral
Interventions: DEVICE: Vestibular Electrical Stimulator and Pinhole Glasses|DEVICE: Vestibular Electrical Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Performance of Contrast-Enhanced Spectral Mammography to Assess Neoadjuvant Chemotherapy Response (CEDM)
Status: TERMINATED
Conditions: Breast Cancer
Interventions: PROCEDURE: Digital Mammography|DRUG: Low Osmolar Contrast Material, 300-399 Mg/Ml Iodine Concentration, Per Ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: TBTC Study 28: Moxifloxacin Versus Isoniazid for TB Treatment
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: Moxifloxacin (with rifampin, pyrazinamide, and ethambutol)|DRUG: isoniazid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing the Harmful Effects of Cannabis Use: Finding the Optimal CBD:THC Ratio
Status: COMPLETED
Conditions: Cannabis Use
Interventions: DRUG: THC|DRUG: Cannabidiol|DRUG: Cannabidiol|DRUG: Cannabidiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Head Position in Stroke Trial (HeadPoST)
Status: COMPLETED
Conditions: Ischemic Stroke|Intracerebral Haemorrhage
Interventions: OTHER: The lying flat (0°) head position for 24 hours|OTHER: The sitting-up (≥30°) head position for 24 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Grounded Theory Study of the Social Determinants of Migrant Health Factors Impacting Prostate Cancer Care and Survivorship Among Sub-Saharan African Immigrant Men Diagnosed With Prostate Cancer
Status: ENROLLING_BY_INVITATION
Conditions: Prostate Carcinoma
Interventions: OTHER: Non-Interventional Study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Abicipar Pegol in Patients With Neovascular Age-related Macular Degeneration
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: abicipar pegol|DRUG: ranibizumab|OTHER: sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on Disposable Sterile Urinary Catheter
Status: TERMINATED
Conditions: Urinary Catheters|Urinary Tract Infection
Interventions: DEVICE: disposable urinary catheter|DEVICE: super smooth antibacterial urinary catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laboratory Treated T Cells in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Non-Hodgkin Lymphoma, or Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: CD19-Positive Neoplastic Cells Present|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Chronic Lymphocytic Leukemia|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Non-Hodgkin Lymphoma|Recurrent Small Lymphocytic Lymphoma|Refractory Acute Lymphoblastic Leukemia|Refractory Chronic Lymphocytic Leukemia|Refractory Diffuse Large B-Cell Lymphoma|Refractory Mantle Cell Lymphoma|Refractory Non-Hodgkin Lymphoma|Refractory Small Lymphocytic Lymphoma
Interventions: BIOLOGICAL: Autologous Anti-CD19CAR-4-1BB-CD3zeta-EGFRt-expressing T Lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABL001 + Dasatinib + Prednisone + Blinatumomab in BCR-ABL+ B-ALL or CML
Status: RECRUITING
Conditions: B-cell Acute Lymphoblastic Leukemia|Chronic Myeloid Leukemia (CML) in Lymphoid Blast Crisis|Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia Ph+ ALL
Interventions: DRUG: ABL001|DRUG: Dasatinib|DRUG: Prednisone|DRUG: Blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth Hormone Treatment in Children Born Small for Gestational Age (SGA)
Status: COMPLETED
Conditions: Foetal Growth Problem|Small for Gestational Age
Interventions: DRUG: somatropin|DRUG: somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Verapamil on the Pharmacokinetics of ASP015K in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Subjects|Pharmacokinetics of ASP015K
Interventions: DRUG: ASP015K|DRUG: verapamil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Floseal® and Tranexamic Acid on Bleeding Control After Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DRUG: Tranexamic acid|DRUG: Floseal®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immune Responses to H5N1 Vaccine With and Without AS03 Adjuvant
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: H5N1 vaccine plus AS03 adjuvant|BIOLOGICAL: H5N1 vaccine without adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Role of Lipoaspirate Injection in the Treatment of Diabetic Lower Extremity Wounds and Venous Stasis Ulcers
Status: WITHDRAWN
Conditions: Diabetic Wounds|Venous Stasis Wounds
Interventions: PROCEDURE: injection of lipoaspirate|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Hyperthermic Intraperitoneal Chemotherapy to Ovarian Cancer Patients With Homologous Recombination Repair Defect and Residual: a Prospective Cohort Study
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: PROCEDURE: HIPEC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Image-Guided Navigation for High Dose Rate Temporary Interstitial Brachytherapy in the Palliative Management of Previously Treated Tumors of the Spine and Pelvis
Status: COMPLETED
Conditions: Metastatic or Recurrent Lesions in the Spine|Metastatic or Recurrent Lesions in the Pelvis
Interventions: RADIATION: Ir-192 high dose rate (HDR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cetuximab in Treating Patients With Precancerous Lesions of the Upper Aerodigestive Tract
Status: COMPLETED
Conditions: Head and Neck Cancer|Precancerous Condition
Interventions: BIOLOGICAL: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Treatment of Postpartum Anemia With Compound E Jiao Jiang(cEJJ）
Status: NOT_YET_RECRUITING
Conditions: Postpartum Anemia
Interventions: DRUG: compound E Jiao Jiang(cEJJ)|DRUG: compound E Jiao Jiang(cEJJ) placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Probiotic Against Respiratory & Gastrointestinal Illnesses in Children
Status: RECRUITING
Conditions: Respiratory Tract Infections
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: reSET for the Treatment of Stimulant Use in HIV Clinics: Care Optimization Supporting Treatment Adherence (COSTA)
Status: NOT_YET_RECRUITING
Conditions: HIV Infections
Interventions: BEHAVIORAL: reSET|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study on Neoadjuvant Radio-Chemotherapy in Rectal Carcinoma Dukes B and C
Status: TERMINATED
Conditions: Rectal Cancer Dukes B, Dukes C
Interventions: DRUG: Fluourouracil|DRUG: Leucovorin|DRUG: MAb 17-1A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phonological Treatment Paired With Intensive Speech Therapy Promotes Reading Recovery in Chronic Aphasia
Status: UNKNOWN
Conditions: Aphasia|Language
Interventions: OTHER: Intensive Phonology Treatment|OTHER: Intensive SFA Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Research on Hybrid Operation Technique in the Treatment of Complex Brain Arteriovenous Malformations
Status: UNKNOWN
Conditions: Cerebrovascular Disease|Arteriovenous Malformations|Complex; Primary
Interventions: PROCEDURE: one-staged hybrid operation|PROCEDURE: Traditional microsurgical operation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Visual Function After Bilateral Implantation of Presbyopia-Correcting Intraocular Lenses (IOLs)
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: AcrySof® IQ ReSTOR® +3.0 D Multifocal IOL Model SN6AD1|DEVICE: AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric IOL Model SND1TT|DEVICE: Acri.LISA® 366D IOL|DEVICE: Acri.LISA® 466TD Toric IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immune Response to Two Doses of rDEN2/4delta30 Dengue Vaccine
Status: COMPLETED
Conditions: Dengue Fever
Interventions: BIOLOGICAL: rDEN2/4delta30(ME) vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Occlusive Skin Closure May Reduce Wound Drainage After Tumor Hip Arthroplasty
Status: COMPLETED
Conditions: Metastatic Bone Disease of the Proximal Femur
Interventions: DEVICE: occlusive wound closure|DEVICE: conventional wound closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BBI608 in Combination With Pemetrexed and Cisplatin in Adult Patients With Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Malignant Pleural Mesothelioma|Non-Small Cell Lung Cancer
Interventions: DRUG: BBI608|DRUG: Pemetrexed|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD19-specific T-cell for Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Advanced Cancers|Leukemia
Interventions: PROCEDURE: Leukapheresis|DRUG: Fludarabine|DRUG: Cyclophosphamide|PROCEDURE: T-cell Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Neurostimulation of the Vagus Nerve for the Treatment of Cluster Headache
Status: COMPLETED
Conditions: Cluster Headache
Interventions: DEVICE: GammaCore|DEVICE: Sham GammaCore device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Effectiveness of the CODMAN ENTERPRISE® Vascular Reconstruction Device
Status: TERMINATED
Conditions: Intracranial Aneurysm
Interventions: DEVICE: CODMAN ENTERPRISE® Vascular Reconstruction Device and Delivery System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Class II Restoration Using Bioactive Restorative Material vs Polyacid Modified Composite Resin in Primary Molars
Status: UNKNOWN
Conditions: Class II Dental Caries
Interventions: PROCEDURE: ACTIVA Bioactive restoration|PROCEDURE: Compomer restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Cell Suspension Grafting Using ReCell in Vitiligo and Piebaldism Patients
Status: COMPLETED
Conditions: Segmental Vitiligo|Piebaldism
Interventions: DEVICE: ReCell|DEVICE: Full surface CO2 laser 200 mJ|DEVICE: Full surface CO2 laser 150 mJ|DEVICE: Fractional CO2 laser 7.5 mJ, 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROJECT PREVENT: Metronidazole Antibiotic Per Vagina Before Hysterectomy: Is Additional Antibiotic Prophylaxis Beneficial?
Status: ACTIVE_NOT_RECRUITING
Conditions: Post-Op Infection
Interventions: DRUG: Metronidazole Vaginal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of First-line Treatment With QL1706 Plus Chemotherapy With or Without Bevacizumab in Women With Recurrent, or Metastatic Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: DRUG: QL1706
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Asenapine With Placebo and Olanzapine (41021)(P05933)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: asenapine|DRUG: Placebo|DRUG: olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of LIPO-202 for the Reduction of Submental Subcutaneous Fat
Status: COMPLETED
Conditions: Submental Fat
Interventions: DRUG: LIPO-202|DRUG: Placebo for LIPO-202
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-finding Study Assessing the Efficacy, Safety, and Pharmacokinetics of Daridorexant in Subjects Aged 10 to < 18 Years With Insomnia Disorder
Status: RECRUITING
Conditions: Insomnia
Interventions: DRUG: Daridorexant 10 mg|DRUG: Daridorexant 25 mg|DRUG: Daridorexant 50 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regenerative Therapy With Autologous Stromal Vascular Fraction Derived Mesenchymal Stem Cells and Platelet-rich Plasma to Treat Complex Perianal Diseases
Status: NOT_YET_RECRUITING
Conditions: Perianal Fistula|Perianal Crohn Disease|Anal Fissure|Rectovaginal Fistula|Perianal Fistula Due to Crohn's Disease
Interventions: PROCEDURE: Regenerative therapy with SVF-PRP to supplement perianal surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Delivered Dietary Intervention for Children With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Abdominal Pain
Interventions: OTHER: Low fermentable substrate diet|OTHER: High fermentable substrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Safety and Immunogenicity of 3 Lots of 20-valent Pneumococcal Conjugate Vaccine in Pneumococcal Vaccine-Naïve Adults
Status: COMPLETED
Conditions: Pneumococcal Disease
Interventions: BIOLOGICAL: 20vPnC|BIOLOGICAL: 20vPnC|BIOLOGICAL: 20vPnC|BIOLOGICAL: 13vPnC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant IMRT Combined With Camrelizumab and Apatinib for Resectable HCC With PVTT
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: COMBINATION_PRODUCT: Neoadjuvant intensity-modulated radiotherapy combined with perioperative camrelizumab and apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise and Patient Education for Patients With Lateral Hip Pain
Status: RECRUITING
Conditions: Gluteal Tendinitis|Greater Trochanteric Pain Syndrome|Hip and Thigh Injury|Rupture of Hip Abductor Tendon (Disorder)
Interventions: PROCEDURE: Exercise and Patient Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Onset of Action of Indacaterol in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Indacaterol|DRUG: Salmeterol/fluticasone (50/500 μg)|DRUG: Salbutamol (200 µg)|DRUG: Placebo to Indacaterol|DRUG: Placebo to Salmeterol/fluticasone|DRUG: Placebo to salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Exploring an Induction-Maintenance Kaletra-Based Therapy Versus a Sustiva-Based Regimen in Previously Non-Treated, HIV-1/HCV Co-Infected Subjects
Status: WITHDRAWN
Conditions: HIV Infection|Hepatitis C
Interventions: DRUG: Kaletra (lopinavir/ritonavir)|DRUG: Sustiva (efavirenz)|DRUG: Truvada (emtricitabine/tenofovir disoproxil fumarate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Hydroxychloroquine in Decreasing Immune Activation in Asymptomatic HIV-infected Patients
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: APixaban vs. PhenpRocoumon in Patients With ACS and AF: APPROACH-ACS-AF
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Atrial Fibrillation|Coronary Artery Disease
Interventions: OTHER: Dual Therapy|OTHER: Triple Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Injection Site Pain and Adherence in Patients Switching From a Low To High Concentration Adalimumab (AVT-02) Across Multiple Indications.
Status: RECRUITING
Conditions: Crohn Disease|Ulcerative Colitis|Rheumatoid Arthritis|Ankylosing Spondylitis|Psoriatic Arthritis|Plaque Psoriasis|Hidradenitis Suppurativa
Interventions: BIOLOGICAL: AVT02 (Alvotech Biosimilar to Adalimumab)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of Low Dose Pioglitazone to Treat Autosomal Dominant Polycystic Kidney Disease
Status: COMPLETED
Conditions: Polycystic Kidney Disease
Interventions: DRUG: Pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Subclinical Cardiovascular Disease in Psoriatic Disease
Status: COMPLETED
Conditions: Cardiovascular Diseases|Myocardial Infarction|Atherosclerotic Cardiovascular Disease|Thrombotic Vascular Disease
Interventions: DRUG: Aspirin and/or Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Doxycycline VS BPG for Early Syphilis (SY-DOXY)
Status: RECRUITING
Conditions: Syphilis
Interventions: DRUG: BPG|DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double Knots Versus Triple Knots Facia Closure Method; is There a Difference in Pain Sensation or Cosmetic Satisfaction?
Status: COMPLETED
Conditions: Cesarean Section|Pain|Cosmetics Sensitivity
Interventions: OTHER: Double knots facia closure method during cesarean section|OTHER: Triple knots facia closure method during cesarean section
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Peer-supported Internet Mediated Psychological Treatment
Status: COMPLETED
Conditions: Psychological Phenomena and Processes|Behavior and Behavior Mechanisms|Mental Disorder|Behavioral Disciplines and Activities
Interventions: BEHAVIORAL: iCBT with addition of peer-support
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Education Intervention to Reduce Ageism Among Undergraduate Students
Status: COMPLETED
Conditions: Ageism
Interventions: BEHAVIORAL: Online educational intervention to reduce ageism|BEHAVIORAL: Online educational intervention to enhance cultural competance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy Plus Filgrastim With or Without Rituximab in Treating Older Patients With Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: prednisone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy of Computerized Cognitive Training in the Elderly With Mild Cognitive Impairment
Status: TERMINATED
Conditions: Mild Cognitive Impairment
Interventions: OTHER: computerized cognitive training|OTHER: occupational therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Mesenchymal Stromal Cells on Sepsis and Septic Shock
Status: COMPLETED
Conditions: Sepsis|Septic Shock
Interventions: BIOLOGICAL: Mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Use of AirXpanders AeroForm in Patients Undergoing Post-Mastectomy Radiation Therapy
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DEVICE: AirXpanders AeroFormtissue expander
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treating Suicidal Behavior and Self-Mutilation in People With Borderline Personality Disorder
Status: COMPLETED
Conditions: Borderline Personality Disorder
Interventions: DRUG: Fluoxetine|BEHAVIORAL: Dialectical Behavior Therapy|BEHAVIORAL: Supportive psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Evidence of Antitumor Activity of FHND5071 as a Single Agent in Adult Patients With Advanced Solid Tumors
Status: ENROLLING_BY_INVITATION
Conditions: Advanced Solid Tumors
Interventions: DRUG: FHND5071
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beneficial Effects of Quinoa (Chenopodium Quinoa Willd) in the Prevention of Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Quinoa and quinoa-based food
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study Of Camrelizumab With Or Without Radiotherapy In The Treatment Of Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: DRUG: Camrelizumab+Radiotherapy|DRUG: Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Statistical Learning as a Novel Intervention for Cortical Blindness
Status: NOT_YET_RECRUITING
Conditions: Stroke, Ischemic|Hemianopia, Homonymous|Hemianopsia|Occipital Lobe Infarct|Visual Field Defect, Peripheral|Vision Loss Partial|Quadrantanopia|Stroke Hemorrhagic
Interventions: DEVICE: Vision Training and Learning Task
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: RF in the Treatment OAB in UUI- a Prospective Randomized Placebo Controlled Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Overactive Bladder Syndrome|Urge Incontinence
Interventions: DEVICE: study group|DEVICE: placebo (sham control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Trial Of Alerts for Use of Mineralocorticoid Receptor Antagonists
Status: COMPLETED
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: BEHAVIORAL: Best Practice Alert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Internet-Based Cognitive Behavioural Program for Managing Stress With IBD: An RCT
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases|Anxiety|Depression|Stress
Interventions: BEHAVIORAL: Cognitive Behavioural Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ENCOMPASS: Expansion Study B, RCT
Status: COMPLETED
Conditions: Hypertension|Diabetes Mellitus, Type 2|Chronic Kidney Diseases|Ischemic Heart Disease|Congestive Heart Failure|Chronic Obstructive Pulmonary Disease|Asthma
Interventions: BEHAVIORAL: Community Health Navigator Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Sugammadex for Muscle Motor Response and Awareness in Intraoperative Wakeup
Status: COMPLETED
Conditions: Spinal Curvatures
Interventions: DRUG: Sugammadex|DRUG: Neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Fetal Endotracheal Occlusion (FETO) in the Resolution of Pulmonary Hypertension in Fetuses With Severe CDH
Status: RECRUITING
Conditions: Congenital Diaphragmatic Hernia
Interventions: DEVICE: Goldbal Detachable Balloon and delivery microcatheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Randomized Active-controlled Study to Investigate Efficacy & Safety of IV FCM in Pediatric Patients With IDA
Status: COMPLETED
Conditions: Iron Deficiency Anemia
Interventions: DRUG: Ferric carboxymaltose|DRUG: Ferrous Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Efficacy and Safety of Anti-Fel d 1 Antibodies Injections in Cat-allergic Adolescent and Adult Patients With Allergic Rhinitis Who Live With a Cat
Status: TERMINATED
Conditions: Allergic Rhinitis Due to Cat Allergy
Interventions: DRUG: REGN1908-1909|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab in Combination With Bevacizumab in Patients With Unresectable Locally Advanced or Metastatic Mucosal Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durability of Pulmonary Vein Isolation Following Cryoablation for Treatment of Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: Arctic Front Advance Cardiac CryoAblation system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Transplantation of Expanded Pancreatic Islet Cells (YD01-2022) in Patients
Status: RECRUITING
Conditions: Diabetes After Total Pancreatectomy
Interventions: BIOLOGICAL: YD01-2022
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Versus Standard Access Cardiac Rehabilitation to Counter Ventricular Remodeling Post-MI (EVADE)
Status: SUSPENDED
Conditions: Myocardial Infarction
Interventions: BEHAVIORAL: Early Access CR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Association of Cephalosporin Resistance and Surgical Site Infections in Patients Undergoing Pancreaticoduodenectomy
Status: COMPLETED
Conditions: Surgical Site Infection|Pancreaticoduodenectomy|Biliary Tract Infection Bacterial
Interventions: PROCEDURE: Preoperative biliary drainage
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of ABT-450 With Ritonavir (ABT-450/r) When Given Together With ABT-333 and Ribavirin (RBV) in Treatment-Naïve and Non-responder Subjects With Genotype 1 Chronic Hepatitis C Virus (HCV) Infection
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection|Hepatitis C|Hepatitis C Virus
Interventions: DRUG: ABT-450|DRUG: ABT-333|DRUG: ribavirin|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Senl_1904A and Senl_1904B Chimeric Antigen Receptor （CAR） T-Cell in the Treatment of r/ r Acute B Lymphocytic Leukemia
Status: UNKNOWN
Conditions: Acute Lymphocytic Leukemia
Interventions: BIOLOGICAL: Autologous CD19-targeting CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improvement of Fluid Balance in Patients Undergoing Surgery of the Colon and Rectum
Status: COMPLETED
Conditions: Colorectal Carcinoma
Interventions: PROCEDURE: Goal-directed fluid optimization|OTHER: Regimen based on expertise anaesthesist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Modified (Retro-Tubercle) Opening Wedge High Tibial Osteotomy Versus the Conventional Technique
Status: COMPLETED
Conditions: Genu Varum
Interventions: PROCEDURE: Retro-Tubercle Opening-Wedge High Tibial Osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT