pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of BIA 9-1067 at Steady-state on the Levodopa Pharmacokinetics
Status: COMPLETED
Conditions: Parkinson's Disease (PD)
Interventions: DRUG: BIA 9-1067|DRUG: Entacapone|DRUG: Placebo|DRUG: Levodopa/carbidopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing the Beneficial Health Effects of Exercise for Diabetes: Focus on the Liver!
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Non-alcoholic Fatty Liver Disease|Obesity
Interventions: BEHAVIORAL: Exercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Experimental, Multicenter, Open-label, Randomized, Controlled Trial of 3-month Dual Antiplatelet Therapy Followed by Ticagrelor Versus 6-month Dual Antiplatelet Therapy Followed by Ticagrelor After Implanting Bridge
Status: RECRUITING
Conditions: Brain Disease|Vertebral Artery Stenosis
Interventions: DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAS-102 in Previously Treated Unresectable or Metastatic Squamous Cell Lung Carcinoma (UF-STO-LUNG-003)
Status: COMPLETED
Conditions: Squamous Cell Lung Carcinoma
Interventions: DRUG: TAS-102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Outcomes for Temporomandibular Disorders (TMD) Via the Clayton Intra-aural Device (CID) Clinical Trial
Status: COMPLETED
Conditions: Temporomandibular Disorders
Interventions: DEVICE: Clayton Intra-aural Device (CID)|DEVICE: Mouth Splint|OTHER: Exercise Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Curcumin Mouthwash in Preventing Traumatic Ulcers in Patients With Fixed Orthodontic Appliances
Status: COMPLETED
Conditions: Oral Ulcer|Orthodontic Appliances, Fixed
Interventions: DRUG: Curcumin mouthwash|DRUG: Placebo mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of MS Ballroom Fitness on Balance, Walking Capacity, and Well-being in Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: MS Ballroom Fitness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SJOV With WNJ in Microlaryngeal Surgery
Status: UNKNOWN
Conditions: Other Complications of Surgical and Medical Procedures
Interventions: DEVICE: WEI NASAL JET (WNJ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Montelukast on Difficulty in Breathing After Exercise in Pediatric Patients (MK0476-377)(COMPLETED)
Status: COMPLETED
Conditions: Exercise-induced Bronchoconstriction (EIB)
Interventions: DRUG: Comparator: montelukast sodium|DRUG: Comparator: Comparator: placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Stockholm Sleepy Brain Study: Effects of Sleep Deprivation on Cognitive and Emotional Processing in Young and Old
Status: COMPLETED
Conditions: Sleep Deprivation
Interventions: BEHAVIORAL: Partial sleep deprivation allowing 3 h sleep at night|BEHAVIORAL: Full sleep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Sugammadex During Transcranial Electrical Motor Evoked Potential Monitoring in Spinal Surgery
Status: COMPLETED
Conditions: Sugammadex
Interventions: DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Neurophysiological Facilitation Techniques in Intensive Care Patients
Status: COMPLETED
Conditions: Intensive Care (ICU) Myopathy|Intensive Care Unit Acquired Weakness
Interventions: OTHER: NPF Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Trial of RAD001 Plus Docetaxel in Patients With Metastatic or Recurrent Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: RAD001|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Levosimendan on Haemodynamics in Patients Undergoing Elective Aortic Valve Replacement (AVR)Together With Coronary Artery Bypass Grafting (CABG) Surgery
Status: COMPLETED
Conditions: Heart Valve Disease
Interventions: DRUG: levosimendan|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Benefits of a Higher Protein, 'Egg-cellent' Breakfast in the Classroom
Status: COMPLETED
Conditions: Breakfast|Obesity|Mood|Eating Behavior
Interventions: OTHER: 'Egg-cellent' Breakfast in the Classroom|OTHER: Breakfast in the Classroom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase 2 Study to Evaluate Analgesic Effect of IV CR845 For Pain Following Bunionectomy Surgery
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: CR845|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ketek in CAP / AECB in Ambulatory Adult Patients
Status: COMPLETED
Conditions: Community Acquired Pneumonia (CAP)|Acute Exacerbation of Chronic Bronchitis (AECB)
Interventions: DRUG: Telithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Daily Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on Proteinuria in Pediatric Patients With Idiopathic Nephrotic Syndrome
Status: COMPLETED
Conditions: Idiopathic Nephrotic Syndrome|Frequently Relapsing Nephrotic Syndrome
Interventions: DEVICE: Transcutaneous Auricular Vagus Nerve (taVNS) stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Evaluation of Psilocybin-Assisted Psychotherapy in Treating Severe Depression in Patients With PTSD
Status: NOT_YET_RECRUITING
Conditions: Post-traumatic Stress Disorder|Depression
Interventions: DRUG: APEX-002-A02|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of RO6807952 in Patients With Diabetes Mellitus Type 2
Status: TERMINATED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Placebo|DRUG: RO6807952|DRUG: RO6807952|DRUG: liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Bioactivity of AXT107 in Subjects With Neovascular Age-Related Macular Degeneration (nAMD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: AXT107 Low Dose|DRUG: AXT107 Mid Dose|DRUG: AXT107 High Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Feeding on Patients With Chronic Obstructive Pulmonary Disease
Status: NOT_YET_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Basic treatment|DEVICE: Oral Tube Feeding|DEVICE: Nasogastric Tube Feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Patient Education With or Without Physical Training or Mindfulness and Medical Yoga in Established Spinal Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis|Vertebral Fracture
Interventions: BEHAVIORAL: Patient education (Theory)|BEHAVIORAL: Physical training|BEHAVIORAL: Mindfulness and medical yoga in group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SYNchronizing Exercises, Remedies in GaIt and Cognition
Status: TERMINATED
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|OTHER: Exercises (E)|OTHER: Cognitive Training (CT)|OTHER: placebo D3|OTHER: control cognitive training|OTHER: Placebo exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Breathalyzer Validation Study
Status: COMPLETED
Conditions: Alcohol Drinking|Alcohol Intoxication
Interventions: DEVICE: Alcohoot|DEVICE: BACtrack Mobile Pro|DEVICE: DRIVESAFE Evoc|DEVICE: BACtrack Vio|DEVICE: Drinkmate|DEVICE: Floome|DEVICE: Intoxilyzer 240
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Acalabrutinib in Combination With Rituximab Versus Ibrutinib Versus Acalabrutinib in Subjects With Relapsed or Refractory Mantle Cell Lymphoma
Status: WITHDRAWN
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: acalabrutinib|DRUG: ibrutinib|DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance (MR) Imaging & Blood Biomarkers for Head and Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cutaneous Squamous Cell Carcinoma of the Head and Neck|Healthy Subject|Head and Neck Cancer
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Magnetic Resonance Imaging|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Brain Relaxation With Mannitol and Furosemide
Status: COMPLETED
Conditions: Brain Tumors
Interventions: DRUG: mannitol|DRUG: Furosemide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pyrazoloacridine Plus Carboplatin in Treating Patients With Recurrent Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: carboplatin|DRUG: pyrazoloacridine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Statin Combination Therapy in Patients Receiving Sorafenib for Advanced Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Overall Survival|Tumor Responses
Interventions: DRUG: Atorvastatin 10mg|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Coronary Artery Disease Progression in Patients With Prediabetes
Status: COMPLETED
Conditions: Coronary Artery Disease|Atherosclerosis|Prediabetic State
Interventions: DRUG: Metformin|BEHAVIORAL: Lifestyle recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness of Injectable Gel for Correction of Infraorbital Hollowing in Chinese Population
Status: RECRUITING
Conditions: Infraorbital Hollowing
Interventions: DEVICE: Cross-linked sodium hyaluronate gel for injection containing lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tucidinostat and Metronomic Capecitabine for Metastatic Triple-negative Breast Cancer:a Multicenter,Open-label, Randomized Controlled, Phase II Clinical Trial
Status: RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Capecitabine|DRUG: Tucidinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adolescent Idiopathic Scoliosis (AIS) Gold Standard for Blood Loss
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: OTHER: Radioisotope I-131-labeled albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ultrasound Evaluation of Lower Extremity Arteries After Topical Nitroglycerin Administration
Status: UNKNOWN
Conditions: Peripheral Arterial Disease
Interventions: DRUG: Nitroglycerin Topical Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma, IDH-wildtype|Glioblastoma|Glioblastoma Multiforme of Brain|Astrocytoma, Malignant|Brain Neoplasms|Brain Neoplasms, Adult, Malignant|Brain Neoplasms, Adult|Recurrent Adult Brain Tumor|Recurrent Glioblastoma
Interventions: PROCEDURE: Awake mapping under local anesthesia|PROCEDURE: Asleep mapping under general anesthesia|PROCEDURE: Resection under general anesthesia without mapping
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tislelizumab Monotherapy or Combined With Lenvatinib as Neoadjuvant Therapy for Resectable Hepatocellular Carcinoma.
Status: NOT_YET_RECRUITING
Conditions: Resectable Hepatocellular Carcinoma
Interventions: DRUG: Tislelizumab|DRUG: Tislelizumab, Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IVIG/Rituximab vs Rituximab in Kidney Transplant With de Novo Donor-specific Antibodies
Status: COMPLETED
Conditions: Renal Transplant
Interventions: DRUG: Rituximab|DRUG: intravenous immune globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Telephone Delivery of Cognitively Augmented Behavioral Activation (CABA)
Status: COMPLETED
Conditions: Traumatic Brain Injury|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Tele-CABA|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tumor Staging T of Bladder Tumours: Correlation of MRI and Anatomopathologic Analysis
Status: NOT_YET_RECRUITING
Conditions: Urinary Bladder Tumour|MRI|Invasion|Diagnosis
Interventions: DIAGNOSTIC_TEST: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the New Acceleromyograph TOF 3D
Status: UNKNOWN
Conditions: Assessment of a New Acceleromyograph|Neuromuscular Block
Interventions: DIAGNOSTIC_TEST: acceleromyography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Combining Talimogene Laherparepvec With BRAF and MEK Inhibitors in BRAF Mutated Advanced Melanoma
Status: UNKNOWN
Conditions: Melanoma|BRAF Gene Mutation
Interventions: DRUG: Talimogene Laherparepvec 1 Million Pfu/Ml Inj,Susp,1Ml,Vil|DRUG: Talimogene Laherparep 100 Mil Pfu/Ml 1Ml|DRUG: Dabrafenib|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Helicobacter Pylori First-line Treatment Containing Tetracycline in Patients Allergic to Penicillin
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Levofloxacin|DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Guanfacine Extended Release and Mindfulness Skills Therapy
Status: WITHDRAWN
Conditions: Stress Disorder
Interventions: DRUG: Guanfacine Extended Release|BEHAVIORAL: Mindfulness Skills Therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Use of Quercetin on Glucose Absorption in Obesity, and Obesity With Type 2 Diabetes
Status: COMPLETED
Conditions: Obesity|Diabetes
Interventions: OTHER: Quercetin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in HIV-1 Infected Patients With Active Illicit Substance usE
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: DRUG: Bictegravir/emtricitabine/tenofovir alafenamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aspiration of Subglottic Secretions Using Hi-Lo Evac Endotracheal Tube: Tube Size and Incidence of Suction Lumen Dysfunction
Status: UNKNOWN
Conditions: Aspiration of Subglottic Secretions
Interventions: DEVICE: Hi-Lo Evac Endotracheal Tube
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Α Prospective Observational Study for the Evaluation of Disease Control and Quality of Life in Patients With Benign PROStatic hyPERplasia Under Fixed Dose combΙnaTion Treatment With Dutasteride and Tamsulosin . PROSPERITY Group of Studies (I&II)
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: OTHER: Patients with Benign Prostate Hyperplasia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Benefit of Spa Care on Severe Radiation-induced Fibrosis After Postoperative Radiotherapy for Breast Cancer
Status: UNKNOWN
Conditions: Breast Carcinoma|Fibrosis
Interventions: OTHER: skin-oriented spa care|DRUG: Pentoxifylline|DRUG: Tocopherol acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Combination of Bendamustine, Bortezomib and Dexamethasone (BBD) in the First-Line Treatment of Patients With Multiple Myeloma Who Are Not Candidates for High Dose Chemotherapy
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Bendamustine|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2a Study to Evaluate Orally Administered ALS-008176 in Adults Hospitalized With a Respiratory Syncytial Virus
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: ALS-008176|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Whole-Body Vibration Therapy in the Gait of Children With Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy|Neurologic Disorder|Gait Disorders in Children|Hemiplegia
Interventions: OTHER: Usual physiotherapy without Whole-Body Vibration|OTHER: Pre-Usual physiotherapy|OTHER: Post-Usual physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Cognitive Function Before and After Induced Ventricular Fibrillation in Electrophysiological (EP) Study
Status: UNKNOWN
Conditions: Ventricular Fibrillation|Ventricular Tachycardia
Interventions: DEVICE: EEG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: NUtraceutical TReatment for hYpercholesterolemia in HIV-infected Patients
Status: COMPLETED
Conditions: Hypercholesterolemia|Inflammation|Atherosclerosis
Interventions: DIETARY_SUPPLEMENT: Nutraceutical combination (NC)|BEHAVIORAL: No nutraceutical combination (noNC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Letrozole in Treating Postmenopausal Women With Stage I, II or III Breast Cancer That Can Be Removed by Surgery
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: letrozole|OTHER: Blood Collection|PROCEDURE: biopsy/lumpectomy/mastectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of XH-S003 in Healthy Volunteers
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: XH-S003 (A)|OTHER: Placebo (B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adequacy of Perioperative Cefuroxime Dosage According to the BMI
Status: COMPLETED
Conditions: Obesity; Drug
Interventions: DRUG: Cefuroxime 1,5g|DRUG: Cefuroxime 3g|DRUG: Cefuroxime 4,5g
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Short-course Radiotherapy or Long-course Chemoradiation Followed by mFOLFOXIRI Consolidation Chemotherapy for Organ Preservation in Low Rectal Cancer
Status: RECRUITING
Conditions: Rectal Neoplasms
Interventions: RADIATION: Short-course radiotherapy|DRUG: Irinotecan|DRUG: Oxaliplatin|DRUG: Calcium Formate|DRUG: Fluorouracil|RADIATION: Long-course chemoradiation|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skin Sensitisation (Modified Draize-95 Test)
Status: COMPLETED
Conditions: Skin Sensitisation
Interventions: DEVICE: Powder Free Polychloroprene Surgical Gloves, Sterile. Low Dermatitis Potential, tested for use with Chemotherapy drugs.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Real-World Study of Pyrotinib Maleate in the Treatment of Advanced/Metastatic Non-Small Cell Lung Cancer With Rare Mutations in HER2
Status: NOT_YET_RECRUITING
Conditions: HER2 Mutant Non-small Cell Lung Cancer
Interventions: DRUG: Pyrotinib maleate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Norwegian Cervical Arthroplasty Trial
Status: COMPLETED
Conditions: Radiculopathy, Cervical
Interventions: PROCEDURE: Cervical arthroplasty|PROCEDURE: Anterior cervical discectomy and fusion (ACDF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A New Antibiotic Prophylaxis Regimen to Prevent Bacteremia Following Dental Procedures
Status: COMPLETED
Conditions: Bacteremia
Interventions: DRUG: Amoxicillin-Potassium Clavulanate|DRUG: Amoxicillin|DRUG: Chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial Evaluating the Benefit of a Fitness Tracker Based Workout During Adjuvant Radiotherapy of Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DEVICE: Fitness tracker based activity training for Arm A and B. Booklet "physical training, exercise and cancer" and an introduction about physical activity during cancer therapy for Arm A, B, C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Minerals and Botanicals for Acute Stress
Status: COMPLETED
Conditions: Stress|Anxiety
Interventions: DIETARY_SUPPLEMENT: Minerals + Vitamins|DIETARY_SUPPLEMENT: Botanical A|DIETARY_SUPPLEMENT: Botanical B|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Ozanezumab (GSK1223249) Versus Placebo in the Treatment of Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Ozanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-Dose or Low-Dose Vorinostat in Combination With Carboplatin or Paclitaxel in Treating Patients With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult Solid Neoplasm
Interventions: DRUG: Carboplatin|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|OTHER: Pharmacological Study|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Lumify™ on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma Patients
Status: NOT_YET_RECRUITING
Conditions: Glaucoma|Glaucoma, Open-Angle|Glaucoma; Drugs|Droopy Eyelid|Ptosis|Glaucoma, Primary Open Angle
Interventions: DRUG: brimonidine tartrate ophthalmic solution 0.025%|OTHER: sterile balanced saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 177Lu-PSMA (177Lu-PNT2002) in PSMA-Positive Adenoid Cystic Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Adenoid Cystic Carcinoma
Interventions: DRUG: 177Lu-PNT2002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin in Insulin Resistant Left Ventricular (LV) Dysfunction (TAYSIDE Trial)
Status: COMPLETED
Conditions: Congestive Heart Failure|Insulin Resistance
Interventions: DRUG: Metformin|DRUG: Matched Placebo (Capsules)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PECS II Versus ICBN Block Plus SCNB for AV Fistula Creation in CRF Patients
Status: COMPLETED
Conditions: Intraoperative Analgesia|Postoperative Pain
Interventions: OTHER: ultrasUltrasound-guided Intercostobrachial nerve block supplemental to supraclavicular block with 30 ml 0.25% bupivacaine (15 ml 0.5% bupivacaine will be added to 15 m|OTHER: ultrasound-guided pectoral nerves block type II supplemental to supraclavicular block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Functional Strength Training of Hip Abductors in Runners With Medial Tibial Stress Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Medial Tibial Stress Syndrome
Interventions: OTHER: Functional strength training of hip abductors|OTHER: A selected physical therapy exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Detection of Human Papillomavirus in Polymerase Chain for Suspicious Lesions of the Amygdala: Concordance Smear-Biopsy
Status: COMPLETED
Conditions: Human Papillomavirus
Interventions: PROCEDURE: Tonsil Biopsy|PROCEDURE: Smear
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Use of Specialised Amino Acid Mixture in Pressure Ulcer Wound Healing Rates- A Placebo Controlled Trial
Status: COMPLETED
Conditions: Pressure Ulcer
Interventions: DIETARY_SUPPLEMENT: Abound (7 g of Arginine, 7 g Glutamine and 1.2 g HMB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anti-VEGF vs. Prompt Vitrectomy for VH From PDR
Status: COMPLETED
Conditions: Proliferative Diabetic Retinopathy|Vitreous Hemorrhage
Interventions: DRUG: 2-mg Intravitreous Aflibercept Injection|PROCEDURE: Prompt Vitrectomy Plus Panretinal Photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Scrambler Therapy for the Reduction of Chemotherapy-Induced Neuropathic Pain
Status: COMPLETED
Conditions: Chemotherapy-Induced Peripheral Neuropathy|Malignant Neoplasm
Interventions: DEVICE: FitBit|OTHER: Gait Assessment Test|OTHER: MC5-A Scrambler Therapy|OTHER: Quality-of-Life Assessment|PROCEDURE: Quantitative Sensory Testing|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: No Drainage During Transoral Endoscopic Thyroidectomy Vestibular Approach(TOETVA)
Status: UNKNOWN
Conditions: Drainage|Thyroid Cancer
Interventions: PROCEDURE: no drainage tube applied
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing Transanal Irrigation With Navina Smart vs. Standard Bowel Care in Patients With Multiple Sclerosis
Status: RECRUITING
Conditions: Neurogenic Bowel (Disorder)|Fecal Constipation|Fecal Incontinence|Multiple Sclerosis
Interventions: DEVICE: Navina Smart|OTHER: Standard Bowel Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TRIple in asthMA With uncontRolled pAtient on Medium streNgth of ICS + LABA
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: CHF 5993 100/6/12.5 µg|DRUG: CHF 1535 100/6 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Acetylcholinesterase Inhibitors on the Gait of the Patients With Parkinson Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DRUG: Donepezil|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serum NGAL Levels in Hemodialysis (HD) Patients; Relation to Iron Status, HD and Intravenous (IV) Iron Administration
Status: UNKNOWN
Conditions: Renal Failure Chronic Requiring Hemodialysis
Interventions: DRUG: Iron Saccharate (Venofer)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Identify if Chemist Confessions Retinol Cream Works to Improve the Appearance of Early Signs of Aging.
Status: COMPLETED
Conditions: Wrinkle|Aging
Interventions: DIETARY_SUPPLEMENT: Retinol face cream|DIETARY_SUPPLEMENT: Placebo face cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Prophylactic Modified McCall Culdoplasty During Total Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Vaginal Vault Prolapse|Sexual Function
Interventions: PROCEDURE: McCall culdoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Benzydamine in Sore Throat Pain Relief (BePaiR Study)
Status: COMPLETED
Conditions: Acute Sore Throat
Interventions: DRUG: 0.3% benzydamine hydrochloride spray oromucosal solution|DRUG: Single 3 mg lozenge of benzydamine hydrochloride (mint flavour)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Local Anesthesia With and Without iPACK Block
Status: RECRUITING
Conditions: Osteo Arthritis Knee|Analgesia|Pain, Postoperative
Interventions: DRUG: Real iPACK block (20 mL of 0.25% bupivacaine, 2.5mcg/mL epinephrine, and 50mcg/mL preservative-free dexamethasone)|DRUG: Sham iPACK block with 20ml normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Effect Tasimelteon on the Cytochrome P450 3A4 and 2C8 Enzymes in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Tasimelteon|DRUG: Rosiglitazone|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neuromuscular Electrical Stimulation After Lung Transplantation
Status: UNKNOWN
Conditions: Lung Transplantation|Electric Stimulation|Clinical Trial
Interventions: OTHER: Neuromuscular electrical stimulation|OTHER: Conventional care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lactulose Supplementation in Premature Infants
Status: COMPLETED
Conditions: Necrotizing Enterocolitis|Sepsis
Interventions: DRUG: Lactulose|DIETARY_SUPPLEMENT: Dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of LY3493269 in Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY3493269|DRUG: Dulaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ixabepilone and Sunitinib Malate in Treating Patients With Progressive Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: Ixabepilone|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cannabis on Dementia Related Agitation and Aggression
Status: COMPLETED
Conditions: Agitation Related to Dementia
Interventions: DRUG: Cannabis|DRUG: Placebo oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Treatment With Insulin VIAjectTM Compared to Regular Human Insulin and Insulin Lispro on Mealtime Blood Vessel Stress in Patients With Type 2 Diabetes Mellitus.
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Regular Human Insulin|DRUG: Insulin Lispro|DRUG: Insulin VIAject™ (75%)|DRUG: Insulin VIAject™ (90%)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Adjuvant Platinum-Doublet Chemotherapy, With or Without Atezolizumab, in Patients Who Are ctDNA Positive After Complete Surgical Resection of Stage IB to Select IIIB Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Carcinoma, Non-Small Cell Lung
Interventions: DRUG: Atezolizumab|DRUG: Placebo|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Pemetrexed|DRUG: Gemcitabine|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transverse Supraumbilical Versus Pfannenstiel Incision For Cesarean Section In Morbidly Obese Women
Status: UNKNOWN
Conditions: Cesarean Section Complications
Interventions: PROCEDURE: Transverse supraumbilical incision|PROCEDURE: Pfannenstiel Incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial Comparing High Tibial Osteotomy Plus Non-Surgical Treatment and Non-Surgical Treatment Alone
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Medial Opening Wedge High Tibial Osteotomy (HTO)|OTHER: Non-Surgical Treatment Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Reduction of IL17 and IL23 Inhibitors in Psoriasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Psoriasis|Psoriasis Vulgaris
Interventions: DRUG: Secukinumab|DRUG: Ixekizumab|DRUG: Brodalumab|DRUG: Guselkumab|DRUG: Risankizumab|DRUG: Tildrakizumab|DRUG: Bimekizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin Alone Versus Atezolizumab Alone Versus Doxorubicin and Atezolizumab in Recurrent Cervical Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Cancer
Interventions: DRUG: Atezolizumab|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Pemigatinib in Subjects With Advanced/Metastatic or Surgically Unresectable Cholangiocarcinoma Who Failed Previous Therapy - (FIGHT-202)
Status: COMPLETED
Conditions: Cholangiocarcinoma
Interventions: DRUG: Pemigatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Host-pathogen Interactions During SARS-CoV-2 Infection
Status: COMPLETED
Conditions: Infection, Coronavirus|Severe Acute Respiratory Syndrome Coronavirus 2
Interventions: BIOLOGICAL: Blood sample|BIOLOGICAL: Low or upper respiratory tract sample|BIOLOGICAL: Stool collection or fecal swab|OTHER: phone call
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Feedback Using behaviOral econOmic Theories on STEP countS in Cardiovascular Disease Patients
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases|Rehabilitation|Behavioral Economics
Interventions: BEHAVIORAL: Gamification (Gain/Loss framing)|BEHAVIORAL: Social support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Investigation of Visual Acuity in Contact Lens Wearers After Instillation of a Lipid- Based Lubricating Eye Drop
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DRUG: Blink® Tears eye drops|DRUG: Investigational lipid eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quinacrine-Capecitabine Combinatorial Therapy for Advanced Stage Colorectal Adenocarcinoma
Status: TERMINATED
Conditions: Colorectal Adenocarcinoma
Interventions: DRUG: Quinacrine and Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance Study of Nova StatStrip® Blood Glucose Monitoring Test System on Neonatal Capillary Blood
Status: SUSPENDED
Conditions: Healthy and Unhealthy Neonates
Interventions: DIAGNOSTIC_TEST: StatStrip blood glucose meter and strips
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Added Value of Reconstructive Lymphatic Surgery to Usual Care in Lymphoedema
Status: RECRUITING
Conditions: Lymphoedema of Leg|Lymphedema Arm|Lymphedema
Interventions: OTHER: Usual care|PROCEDURE: Reconstructive lymphatic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Distribution of a Tenofovir Douche With Tap Water Douching and Simulated Receptive Anal Intercourse
Status: COMPLETED
Conditions: HIV/AIDS|HIV Prevention
Interventions: DRUG: Tenofovir Douche
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Innovations to Prevent Relapse Among Low-income African American Smokers
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: OTHER: Nicotine replacement therapy (NRT)|BEHAVIORAL: CS-CBT intervention|BEHAVIORAL: Path2Quit|BEHAVIORAL: Relapse prevention program|BEHAVIORAL: SmokefreeTXT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Effect of Fluticasone Furoate/Vilanterol on Survival in Subjects With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: fluticasone furoate/vilanterol|DRUG: fluticasone furoate|DRUG: vilanterol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Human Adipose Derived Mesenchymal Stem Cells for Critical Limb Ischemia (CLI) in Diabetic Patients
Status: COMPLETED
Conditions: Critical Limb Ischemia (CLI)|Diabetes
Interventions: DRUG: Autologous adipose derived mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Postspinal Anesthesia Hypotension During Elective Cesarean Section: Baby Norepinephrine Versus Ephedrine
Status: NOT_YET_RECRUITING
Conditions: Anesthesia Complication|Vasopressor|Cesarean Section Complications|Hypotension During Surgery
Interventions: DRUG: Norepinephrine|DRUG: Ephedrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Corneal Lesions in Intensive Care Unit (ICU) Clinical Trial for Proposing Interventions and Evaluating Outcomes of Nursing in the Adult Intensive Care Center Clinical Trial for Proposing Interventions and Evaluating Outcomes of Nursing in the Adult Intensive Care Center
Status: COMPLETED
Conditions: Keratitis|Corneal Ulcer
Interventions: DEVICE: LACRIBELL®|DEVICE: LIPOSIC®|DEVICE: Glad wrap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Treating Deep Seizure Foci With Noninvasive Surface Brain Stimulation
Status: COMPLETED
Conditions: Epilepsy, Temporal Lobe
Interventions: DEVICE: Low-frequency repetitive transcranial magnetic stimulation|DEVICE: High-frequency repetitive transcranial magnetic stimulation|DEVICE: Sham repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study to Characterize the Incidence and Severity of Diarrhea in Patients With Early-Stage HER2+ Breast Cancer Treated With Neratinib and Loperamide
Status: COMPLETED
Conditions: Early Stage HER2+ Breast Cancer
Interventions: DRUG: Neratinib|DRUG: Loperamide|DRUG: Colestipol|DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a New Knee Brace for Treatment of the Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Stabilizing Knee Brace|DEVICE: Valgus Knee Brace|DEVICE: New Knee Brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Hypothermia Therapy in Pediatric Cardiac Intensive Care Unit for Suspected for Brain Injury
Status: UNKNOWN
Conditions: Congenital Heart Defects|Brain Ischemia|Hypoxia Brain|Child|Hypothermia, Induced
Interventions: DEVICE: Whole body hypothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Validation Study of Albumin Kinetics With Tracer 123 I-HSA
Status: COMPLETED
Conditions: Healthy|SIRS
Interventions: OTHER: 123 I-HSA + 125 I HSA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Collaborative Nursing Care-based Intervention in Mental Health Day Hospital Users
Status: COMPLETED
Conditions: Care Acceptor, Health|Nurse's Role|Relationship, Nurse Patient|Mental Health Disorder|Mental Health Wellness 1
Interventions: BEHAVIORAL: Collaborative cares
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Applicability of Enhanced Recovery After Surgery Protocols in the Therapeutic Endoscopy Suite
Status: NOT_YET_RECRUITING
Conditions: Colorectal Endoscopic Submucosal Dissection
Interventions: PROCEDURE: ERAS protocols
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE