pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Efficacy of PEG-rhG-CSF in Preventing Neutropenia in Children With Tumor After Chemotherapy
Status: UNKNOWN
Conditions: Pediatric Cancer
Interventions: DRUG: pegylated recombinant human granulocyte-colony stimulating factor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Bilateral Suprazygomatic Maxillary Nerve Block and Bimaxillary Osteotomy
Status: COMPLETED
Conditions: Dentofacial Deformities|Regional Anesthesia Morbidity
Interventions: PROCEDURE: Infiltration|PROCEDURE: Maxillary nerve blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: THE EFFECTS OF SUBTALAR JOINT MOBILIZATION ON PATIENTS WITH CHRONIC STROKE
Status: COMPLETED
Conditions: Hemiplegia, Spastic
Interventions: OTHER: Talocrural joint MWM mobilization|OTHER: Subtalar joint MWM mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Effectiveness and Safety of Golcadomide Plus R-CHOP vs Placebo Plus R-CHOP in Participants With Previously Untreated High-risk Large B-cell Lymphoma
Status: RECRUITING
Conditions: Large B-cell Lymphoma
Interventions: DRUG: Golcadomide|DRUG: Placebo|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Safety Study of Topical Diltiazem Hydrochloride
Status: UNKNOWN
Conditions: Diltiazem Skin Sensitivity.
Interventions: DRUG: Diltiazem Hydrochloride 2% Cream|DRUG: Vehicle Cream|DRUG: 0.1% solution of sodium lauryl sulfate (SLS)|DRUG: Saline (0.9%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MRI in Predicting Response in Patients Receiving Combination Chemotherapy and Bevacizumab For Advanced or Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: S8600-S9031-S9333-A, Study of DNA in Samples From Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: DNA methylation analysis|GENETIC: gene expression analysis|GENETIC: microarray analysis|OTHER: laboratory biomarker analysis|OTHER: medical chart review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: En Masse Distaliaztion Via Skeletal Anchorage
Status: UNKNOWN
Conditions: Orthodontic Appliance Complication, Angle Class II Patients, Distalization
Interventions: DEVICE: Distalization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Consumption of Eggs in the Context of Plant-Based Diets on Endothelial Function, Diet Quality, and Cardio-Metabolic Risk Factors in Adults at Risk for Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Cardiovascular Diseases
Interventions: OTHER: Egg included vegan phase|OTHER: Vegan Phase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Safety and Efficacy of Two Different Drug Eluting Stents Implanted Into Saphenous Vein Grafts
Status: UNKNOWN
Conditions: Stenosis in Saphenous Vein Graft, Drug Eluting Stent
Interventions: DEVICE: Taxus stent implantation|DEVICE: Luc-Chopin stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy, Immunogenicity and Safety Study Investigating an Adjuvanted SARS-CoV-2 Influenza Vaccine to Protect Against COVID-19 in Adults Over Aged 18 Years-old and Older
Status: WITHDRAWN
Conditions: Influenza
Interventions: DRUG: Adjuvanted SARS-CoV-2 Subunit vaccine (aCoV2)|DRUG: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Single and Multiple Ascending Dose Study to Evaluate the Safety, Pharmacokinetics, and Target Engagement of BMS-986147 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BMS-986147|DRUG: Placebo matching BMS-986147
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Estimation of the Safety and Efficiency Transfusion of HLA Matched CBU in Patients With CP
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: BIOLOGICAL: Low HLA group CBU infusion|BIOLOGICAL: High HLA group CBU infusion|OTHER: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of TCC-EZ Using Human Amnion Allograft vs TCC-EZ and Standard Wound Care in Treating Diabetic Foot Ulcers.
Status: UNKNOWN
Conditions: Diabetic Foot Ulcers|Diabetes
Interventions: DEVICE: Topical wound dressing|BIOLOGICAL: Human Amnion Allograft|OTHER: usual wound care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy of FFP From Healthy Donors to AmeliorateFrailty and Enhance Immune Function in Older Individuals
Status: ENROLLING_BY_INVITATION
Conditions: Frailty
Interventions: DRUG: GMFFP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Poorly Differentiated Adenocarcinoma With Signet Ring Cells of the Gallbladder Producing a High Level of Alpha-fetoprotein: a Case Report
Status: COMPLETED
Conditions: Gallbladder Cancer
Interventions: PROCEDURE: laparoscopic whole-layer cholecystectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2
Status: RECRUITING
Conditions: Urothelial Carcinoma
Interventions: DRUG: disitamab vedotin|DRUG: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Bruegger's Versus Kendall Exercises in Cervical Postural Syndrome
Status: NOT_YET_RECRUITING
Conditions: Neck Pain
Interventions: OTHER: Brugger's Exercises|OTHER: Kendal Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Interactions Between Morphine and Orally or IV Administered Acetaminophen
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Oral Acetaminophen|DRUG: IV Acetaminophen|DRUG: IV Morphine|DRUG: Placebo Tablets|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Brain Imaging in Men With Lower Urinary Tract Symptoms
Status: COMPLETED
Conditions: Voiding Disorders
Interventions: DIAGNOSTIC_TEST: Simultaneous functional MRI and urodynamic studies|BEHAVIORAL: Questionnaires|OTHER: Post Void Residual (PVR), Uroflow and Bladder Diary|DIAGNOSTIC_TEST: Urinalysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mechanisms Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 3
Status: RECRUITING
Conditions: Heart Failure
Interventions: DRUG: LCZ 696|DRUG: Placebo|DRUG: Para-aminohippurate|DRUG: Iohexol|DRUG: Aprepitant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Shear Wave Elastography Versus Strain Elastography With Histogram Analysis in Solid Pancreatic Lesions
Status: UNKNOWN
Conditions: Endoscopic Ultrasonography
Interventions: DIAGNOSTIC_TEST: Elastography EUS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of a Self-rehabilitation Program in Addition to Usual Treatment for Spasticity on Impairment and Activity Limitation in Patients With Spastic Hemiparesis Following Stroke
Status: UNKNOWN
Conditions: Spastic Hemiparesis
Interventions: OTHER: Self-rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pollen Season on Subcutaneous Allergen Immunotherapy Reactions
Status: UNKNOWN
Conditions: Allergic Rhinitis|Asthma|Allergic Conjunctivitis
Interventions: DRUG: Allergen(Tree, Grass, Weeds)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Suramin, Paclitaxel, and Carboplatin in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: suramin|DRUG: carboplatin|DRUG: paclitaxel|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACTOplus Met XR in Treating Patients With Stage I-IV Oral Cavity or Oropharynx Cancer Undergoing Definitive Treatment
Status: TERMINATED
Conditions: Oral Cavity Neoplasm|Oropharyngeal Neoplasm|Stage 0 Oral Cavity Squamous Cell Carcinoma American Joint Committee on Cancer (AJCC) v6 and v7|Stage 0 Oropharyngeal Squamous Cell Carcinoma AJCC v6 and v7|Stage I Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7|Stage I Oropharyngeal Squamous Cell Carcinoma AJCC v6 and v7|Stage II Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7|Stage II Oropharyngeal Squamous Cell Carcinoma AJCC v6 and v7|Stage III Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7|Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7|Stage IVA Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7|Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7|Stage IVB Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7|Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Metformide Hydrochloride/Pioglitazone Hydrochloride Extended-Release Tablet|OTHER: Pharmacological Study|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Can we Use Estrogen-containing Therapy to Improve Pain in Women After Menopause With Hand Osteoarthritis?
Status: COMPLETED
Conditions: Hand Osteoarthritis
Interventions: DRUG: Estrogen-bazedoxifene|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Aortic Valve Regurgitation Acquired After Left Ventricular Assist Device Implantation: an Outstanding in Vivo Model of Valvular Heart Diseases
Status: SUSPENDED
Conditions: Aortic Valve Regurgitation Acquired
Interventions: BIOLOGICAL: blood samples|BIOLOGICAL: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CLONICEL (Clonidine Sustained Release) as Add-on to Stimulant Medication in 6 to 17 Yr-olds With ADHD
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: CLONICEL (clonidine HCl sustained release)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Resistance Training on Energy Intake and Appetite Regulation, 12-weeks Resistance Training
Status: UNKNOWN
Conditions: Overweight|Obese
Interventions: DEVICE: resistance training|DEVICE: Normal P.E. course
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Behavioral Consultation for HIV+ Older Adults Prescribed Opioids for Chronic Pain
Status: COMPLETED
Conditions: Opioid Misuse|Older Adults|HIV
Interventions: BEHAVIORAL: Choacot: Behavioral Intervention for Chronic Opioid Use|OTHER: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A PhaseI/IIa Study to Determine the Safety and Tolerability of MA09-hRPE Cells in Patients With Advanced Dry AMD
Status: TERMINATED
Conditions: Dry Age Related Macular Degeneration
Interventions: BIOLOGICAL: MA09-hRPE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of AMATEA™️ on Physiological Measures and Gaming Performance in Active Gamers: a Placebo Controlled, Double-blind, Randomized Study
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: AMATEA™|DIETARY_SUPPLEMENT: Caffeine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Net Ultrafiltration Challenge to Predict Preload-dependence (UF CHALLENGE)
Status: RECRUITING
Conditions: Acute Kidney Injury
Interventions: DIAGNOSTIC_TEST: Fast ultrafiltration challenge|DIAGNOSTIC_TEST: Slow ultrafiltration challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study in People With Colorectal Cancer to Test Whether Ezabenlimab or Pembrolizumab in Combination With BI 765063 Lead to Side Effects or Delays in Surgery
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: Ezabenlimab|DRUG: BI 765063|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Three Doses of OPC-8212 (Vesnarinone) in HIV-Infected Persons With CD4+ Cell Number > 300 Cells/mm3
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Vesnarinone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real World Evidence of the Efficacy and Safety of FOQUEST
Status: COMPLETED
Conditions: Attention Deficit-Hyperactivity Disorder
Interventions: DRUG: Methylphenidate Hydrochloride|DRUG: Lisdexamfetamine Dimesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Copenhagen Mesenteric Stent Study - A Randomized Trial of Stent Versus Covered Stent Treatment for Chronic Mesenteric Ischemia
Status: RECRUITING
Conditions: Mesenteric Ischemia|Bowel; Ischemic|Superior Mesenteric Atherosclerosis|Mesenteric Artery Stenosis|Stent Restenosis|Stent Occlusion|Stent Thrombosis|Stent-Graft Stenosis|Stent-Graft Thrombosis|Stent-Graft Restenosis
Interventions: DEVICE: BMS vs. CS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate L9LS in Healthy Adults
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: VRC-MALMAB0114-00-AB|OTHER: Plasmodium falciparum (P. falciparum) sporozoite challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Durvalumab and Tremelimumab Plus Radiation for High Risk Soft-Tissue Sarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Soft Tissue Sarcoma
Interventions: COMBINATION_PRODUCT: Combination Radiation, Immunotherapy, Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Stress Reduction in the Secondary Prevention of Coronary Heart Disease in Blacks
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: BEHAVIORAL: Cardiac Rehabilitation plus Transcendental Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Assessment and Treatment of Balance Impairment Using Virtual Reality (VR) in Panic Disorder Patients
Status: UNKNOWN
Conditions: Panic Disorder|Proprioceptive Disorders
Interventions: DEVICE: VR movie + balance challenge|DEVICE: still pictures from VR|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Establishment of a Tumor Bank for Tissue Samples
Status: RECRUITING
Conditions: Ovarian Neoplasms|Breast Neoplasms|Colorectal Neoplasms|Neoplasms of the Female Genitalia|Lung Neoplasms|Endocrine Gland Neoplasms
Interventions: OTHER: Tumor tissue collection|OTHER: Sampling of ascites and pleural effusion|OTHER: Collecting urine samples|OTHER: Collecting saliva sample|OTHER: Collecting sputum|OTHER: Collecting stool samples|OTHER: Lavage/Irrigation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Naltrexone in the Treatment of Trichotillomania
Status: COMPLETED
Conditions: Trichotillomania
Interventions: DRUG: Naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Frenuloplasty for Speech and Myofunctional Outcomes
Status: NOT_YET_RECRUITING
Conditions: Ankyloglossia|Speech Delay|Dentofacial Abnormalities
Interventions: PROCEDURE: Lingual frenuloplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Model to Predict pCR and IrAEs in Early Stage Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer Stage IB (Resectable)|Non-small Cell Lung Cancer Stage II (Resectable)|Non-small Cell Lung Cancer Stage ⅢA (Resectable)
Interventions: OTHER: Observational
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Patients Navigators in Facilitating Weight Management in Obese Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Health Status Unknown|Obesity
Interventions: OTHER: Informational Intervention|OTHER: Questionnaire Administration|BEHAVIORAL: Telephone-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prognostic Impact of the Neutrophil/Lymphocyte Ratio (NLR) in the Treatment of First-line Metastatic or Locally Advanced Breast Cancer Treated With CDK4/6 Inhibitor.
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Metastatic Breast Cancer
Interventions: BIOLOGICAL: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of the Efficacy and Safety of NVA237 in Patients With Moderate to Severe COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: NVA237|DRUG: Placebo|DRUG: Salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study on Trans-umbilical Single-port Laparoscopic Extra-peritoneal Approach Versus Conventional Repair for Inguinal Hernia in Children
Status: UNKNOWN
Conditions: Inguinal Hernia,Laparoscopy,Extra-peritoneal
Interventions: PROCEDURE: extra-peritoneal high ligation of hernia|PROCEDURE: intraabdominal high ligation of hernia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of HIIT on Metabolic Syndrome
Status: UNKNOWN
Conditions: Dyslipidemias|Metabolic Syndrome|Sedentary Behavior|Obesity|Blood Pressure
Interventions: BEHAVIORAL: Low Volume-High Intensity Interval Training|BEHAVIORAL: Moderate Intensity Continuous Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Motivational Interview as a Strategy in the Reduction of Blood Pressure.
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Motivational interviewing|BEHAVIORAL: Prescriptive Consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy and Bevacizumab With or Without Bevacizumab Maintenance Therapy in Treating Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: FOLFIRI regimen|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Relationship Between Environmental Risk Factors in Housing Types and Chronic Respiratory Diseases in Ho Chi Minh City
Status: COMPLETED
Conditions: Chronic Respiratory Diseases
Interventions: OTHER: Questionnaire|DEVICE: Lung function test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: NL-201 Monotherapy and in Combination With Pembrolizumab in Patients With Relapsed or Refractory Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor|Advanced Solid Tumor
Interventions: DRUG: NL-201|DRUG: Pembrolizumab Injection [Keytruda]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Cinobufacini Combined With Transarterial Chemoembolization (TACE) on Primary Liver Cancer
Status: UNKNOWN
Conditions: Liver Cancer
Interventions: DRUG: Cinobufacini injection|PROCEDURE: Transarterial Chemoembolization(TACE)|DRUG: cinobufacini tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pcv-aCO2 in the Fluid Treatment of Abdominal Tumor Patients After Surgery
Status: UNKNOWN
Conditions: Abdominal Tumor|Abdominal Infection
Interventions: OTHER: standardized fluid therapy|OTHER: conventional fluid therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multidisciplinary Perioperative Care Pathway in Adolescents Undergoing Posterior Spinal Fusion Surgery
Status: COMPLETED
Conditions: Analgesia|Scoliosis Idiopathic|Surgery|Postoperative Pain
Interventions: OTHER: Enhanced recovery pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tetracycline Treatment Tolerability Trial
Status: ENROLLING_BY_INVITATION
Conditions: Post-Treatment Lyme Disease
Interventions: DRUG: Tetracycline 500 Mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Viome Nutritional Programs to Improve Clinical Outcomes for Gastrointestinal Conditions
Status: RECRUITING
Conditions: Gastrointestinal Health
Interventions: COMBINATION_PRODUCT: VIOME Precision Nutrition Program|DIETARY_SUPPLEMENT: VIOME-designed condition-based supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Explore the Third-line Treatment of Fruquintinib Combined With Serplulimab in Advanced Non-isolated Hepatic Metastatic Colorectal Cancer: a Single-center, Phase 2 Study
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: serplulimab|DRUG: Fruquintinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Controlled Trial on the Efficacy and Safety of Live-Attenuated Influenza Vaccine (LAIV) Among Children in Bangladesh
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: SIIL Live Attenuated Influenza Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tobacco Intervention in Primary Care Treatment Opportunities for Providers
Status: COMPLETED
Conditions: Smoking|Smoking Cessation
Interventions: OTHER: Nicotine Replacement Therapy (NRT) Sampling|BEHAVIORAL: Ask, Advise, Refer (physician brief advice)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Confirmatory Study of 17P vs Vehicle for Prevention of Preterm Birth in Women w/ Previous Spontaneous Preterm Delivery
Status: COMPLETED
Conditions: Preterm Birth
Interventions: DRUG: Hydroxyprogesterone Caproate Injection (HPC), 250mg/mL|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment to Reduce Vascular Calcification in Hemodialysis Patients Using Vitamin K
Status: COMPLETED
Conditions: Vascular Calcification|Systemic and Arterial Stiffness|Complication of Hemodialysis|Deficiency of Vitamin K2
Interventions: DRUG: menaquinone-7
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of 2PX in Patients With Pain Due to Osteoarthritis of the Knee
Status: UNKNOWN
Conditions: Pain|Osteoarthritis
Interventions: DRUG: strontium chloride hexahydrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Triple Therapy With Peg-Interferon Alfa-2b/Ribavirin Plus Amantadine Compared to Standard Peg-Interferon Alfa-2b/Ribavirin for Previous Hepatitis C Virus (HCV) Non Responders
Status: TERMINATED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: peg-interferon alfa-2b|DRUG: ribavirin|DRUG: amantadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Prior Exposure to Conflicting Health Information on Responses to Subsequent Unrelated Health Messages
Status: COMPLETED
Conditions: Communication Research
Interventions: OTHER: Exposure to conflicting health information|OTHER: No exposure to conflicting health information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Giving Resources to lOw-income Children to Enhance RecoverY
Status: NOT_YET_RECRUITING
Conditions: Discharged Pediatric Patients and Their Families
Interventions: OTHER: Grocery gift card
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Fetal and Neonatal Thyroid in Pregnancies With Severe Acute Respiratory Syndrome Coronavirus 2 ( SARS- COV2 ) COVID-19
Status: COMPLETED
Conditions: Thyroid Dysfunction|Hypothyroidism|Hyperthyroidism
Interventions: DRUG: Thyroxine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Telehealth to Improve Prevention of Suicide (TIPS)
Status: RECRUITING
Conditions: Suicide Risk
Interventions: OTHER: Telehealth in preventing suicide (TIPS)|OTHER: Modified ED-SAFE|OTHER: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Novel Lung Trial: Normothermic Ex Vivo Lung Perfusion (Evlp) As An Assessment Of Extended/Marginal Donor Lungs
Status: UNKNOWN
Conditions: Lung Transplant
Interventions: DEVICE: XPS™ with Steen Solution™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of IV Vitamin C, Thiamine, and Steroids on Mortality of Septic Shock
Status: TERMINATED
Conditions: Septic Shock
Interventions: DRUG: Vitamin C|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Dose and Formulation Confirmation of Quad-NIV in Older Adults
Status: TERMINATED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: NanoFlu (Quad-NIV)|OTHER: Matrix-M Adjuvant|OTHER: Placebo|BIOLOGICAL: Fluzone HD|BIOLOGICAL: Flublok Quadrivalent|BIOLOGICAL: Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficiency of a Telemedicine-based Follow-up on for the Medical Management of Patients Leaving the Intensive Care Unit
Status: NOT_YET_RECRUITING
Conditions: Care After Going to Intensive Care
Interventions: DEVICE: Monitoring by Tele-Medecine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Guided Femoral Nerve Block Catheter Analgesia Compared With Epidural Analgesia for Patients With Knee OA (Osteoarthritis) Who Underwent Unilateral Total Knee Replacement
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: OTHER: Ultrasound guided femoral nerve block catheter analgesia compared with epidural analgesia for patients with knee OA (osteoarthritis)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multi-Modality Imaging for Head & Neck Cancer Free Flap Design Assessment
Status: TERMINATED
Conditions: Head and Neck Neoplasms
Interventions: PROCEDURE: Pre-op CTA with IV contrast|DEVICE: Computed tomography angiography (CTA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cohort Study Investigating the Association Between Antichlamydial Antibody Positivity and ART Outcomes in Women With TFI
Status: UNKNOWN
Conditions: Antichlamydial Antibodies|Chlamydia Trachomatis Infection|Infertility|Tubal Factor Infertility
Interventions: DIAGNOSTIC_TEST: antichlamydial antibody test|DRUG: treatment of infertility with ART
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Prospective Clinical Trial Comparing Serum Mast Cell Tryptase (SMCT) Levels to Arthrofibrosis Rates Among Primary Total Knee Arthroplasty (TKA) Patients
Status: COMPLETED
Conditions: Knee Osteoarthritis|Arthropathy of Knee|Arthrofibrosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Importance of Needle Gauge for Pain During Injection of Local Anaesthetic
Status: COMPLETED
Conditions: Needlestick Injuries
Interventions: PROCEDURE: Large needle gauge lidocaine injection|PROCEDURE: Normal needle gauge lidocaine injection|PROCEDURE: Small needle gauge lidocaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Endothelial Dysfunction Using the "Flow Mediated Dilation" Test in a Population of Chronic Renal Failure Patients at Different Stages, and Evaluation of the Role of Antiphospholipid Antibodies
Status: RECRUITING
Conditions: Chronic Renal Failure
Interventions: PROCEDURE: Urine sampling|PROCEDURE: Blood sampling|DEVICE: Flow mediated dilatation test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tele-Mindfulness for Dementia's Family Caregivers: a Randomized Trial With a Usual Care Control Group
Status: COMPLETED
Conditions: Caregivers|Mindfulness
Interventions: BEHAVIORAL: Tele-MBCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Teriparatide and Strontium Ranelate Head-To-Head Comparison Trial
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Teriparatide|DRUG: Strontium ranelate|PROCEDURE: Transiliac bone biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oncology Dashboard for the Improvement of Operational Efficiency and Patients Outcomes in Patients With Sarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcoma
Interventions: OTHER: Best Practice|OTHER: Informational Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Staining Potential and Caries Arresting Effect of Silver Diamine Fluoride⁄Potassium Iodide and Silver Diamine Fluoride
Status: UNKNOWN
Conditions: Dental Caries in Children
Interventions: DRUG: silver diamine fluoride ⁄ potassium Iodide|DRUG: Silver Diamine Fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sensor-controlled Digital Game for Heart Failure Self-management: A Clinical Trial
Status: RECRUITING
Conditions: Heart Failure
Interventions: BEHAVIORAL: Sensor-controlled digital game (SCDG)|BEHAVIORAL: Sensor Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial
Status: TERMINATED
Conditions: Ischemic Attack, Transient
Interventions: DRUG: Clopidogrel|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Evaluate Safety and Pharmacokinetics of FZJ-003 in Healthy Volunteers
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DRUG: FZJ-003|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Different Digital Methods in Occlusal Analysis
Status: COMPLETED
Conditions: Dental Occlusion|Occlusion|Jaw Relationship|Centric Occlusion|Occlusal Analysis
Interventions: DEVICE: Digital Occlusal Recording with T-Scan|DEVICE: Digital Occlusal Recording with Cerec Omnicam
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anosmia and / or Ageusia and Early Corticosteroid Use
Status: RECRUITING
Conditions: Covid19|Anosmia
Interventions: DRUG: Early-Dexamethasone|DRUG: Late dexamethazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Modified Release AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias
Status: COMPLETED
Conditions: Dyskinesias|Parkinson Disease|Movement Disorders|Parkinsonian Disorders|Anti-Dyskinesia Agents
Interventions: DRUG: AFQ056|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TEAS Enhanced Recovery After Laparoscopic Colon Surgery
Status: COMPLETED
Conditions: Postoperative Recovery
Interventions: OTHER: TEAS|OTHER: false stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy of HLA-A2 Positive Stage III/IV Melanoma Patients
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: group 1|BIOLOGICAL: group 2|BIOLOGICAL: group 3|BIOLOGICAL: group 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Chiropractic Care on Cytokine Levels in Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: OTHER: Spinal Manipulation|OTHER: Sham Spinal Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intermittent Versus Continuous Subglottic Secretion Drainage on Tracheal Mucosa Damages
Status: TERMINATED
Conditions: Mechanical Ventilation Complication
Interventions: DEVICE: Intermittent subglottic secretion drainage|DEVICE: Continuous subglottic secretion drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics and Safety Study of Cabazitaxel in Cancer Patients With Renal Impairment
Status: COMPLETED
Conditions: Neoplasm Malignant
Interventions: DRUG: Cabazitaxel XRP6258
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Benefit of Hypnoanalgesia Versus Neuroleptanalgesia During Hand Surgery
Status: RECRUITING
Conditions: Hand Surgery
Interventions: DRUG: Neurloeptanalgesic treatment|OTHER: Hypnoanalgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Wearable Assisted Viral Evidence (WAVE) Study A Decentralized, Prospective Study Exploring the Relationship Between Passively-collected Data From Wearable Activity Devices and Respiratory Viral Infections
Status: COMPLETED
Conditions: Influenza, Human|COVID-19|Influenza A|Influenza B|Respiratory Syncytial Virus (RSV)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Continuous Non-invasive Hemodynamic Monitoring in Early-onset Severe Preeclampsia: a Comparison of Echocardiography, Bioreactance, and Finger Cuff Measurements
Status: COMPLETED
Conditions: Pre-Eclampsia
Interventions: DIAGNOSTIC_TEST: Echocardiogrpahy and non-invasive monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SPECT Investigation Of The NMDA Receptor System In Healthy Volunteers And Patients With Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: [123]I-CNS 1261|DRUG: Lorazepam|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Radiation Dose in Humans From Orally Administered Tc99m-Heparin
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: RADIATION: Computerized Tomography scan|RADIATION: Single Photon Emission Computed Tomography scans|DRUG: Technetium Tc 99M|RADIATION: Planar Images|PROCEDURE: Esophagogastroduodenoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sorafenib and Everolimus in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma
Status: COMPLETED
Conditions: Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: RAD001|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Vorinostat in Patients With Relapsed or Refractory DLBCL, FCL or HL.
Status: ACTIVE_NOT_RECRUITING
Conditions: Grade 3b Follicular Lymphoma|Recurrent B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between DLBCL and Classic HL|Recurrent Classic Hodgkin Lymphoma|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Follicular Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3a Follicular Lymphoma|Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma|Recurrent Transformed Non-Hodgkin Lymphoma|Refractory B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between DLBCL and Classic HL|Refractory Classic Hodgkin Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Follicular Lymphoma|Refractory Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma|Refractory Transformed Non-Hodgkin Lymphoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Online Exercises for Premenstrual Syndrome on Couple's Stress and Family Function
Status: NOT_YET_RECRUITING
Conditions: Premenstrual Syndrome|Exercises|Stress Level|Family Characteristics
Interventions: OTHER: Progressive Relaxation Exercises, randomized pretest-posttest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vapor Ablation for Localized Cancer Lesions
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer|Metastatic Lung Cancer|Lung Cancer
Interventions: DEVICE: Bronchoscopic Thermal Vapor Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of On-Q Pump for Pain Post C-Section
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ropivacaine 0.1%|DRUG: Ropivacaine 0.2%|DRUG: Normal saline|DEVICE: On-Q ® elastomeric pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Two Daily Disposable Contact Lenses Over 1-week of Wear
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: delefilcon A|DEVICE: etafilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Activity on Prescription to Promote Physical Activity in Hospitalized Patients
Status: UNKNOWN
Conditions: Physical Activity
Interventions: PROCEDURE: "Prescription for Activity" and individual instructions|OTHER: "Prescription for Activity", without instructions|OTHER: usual physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oral Health Intervention in Adult Primary Care
Status: NOT_YET_RECRUITING
Conditions: Dental Caries|Dry Mouth|Periodontal Diseases|Bleeding Gum
Interventions: BEHAVIORAL: EHR Changes|BEHAVIORAL: Medical Staff EHR Training, Clinician CSM theory-based didactic education and skills training|BEHAVIORAL: Standard ADA Oral Health Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Enhancement of Contrast Opacification for Echocardiographic Imaging of the Right Heart and Shunts
Status: COMPLETED
Conditions: Bidirectional Cardiovascular Shunt
Interventions: PROCEDURE: Transesophageal Echocardiogram (TEE)|PROCEDURE: Transthoracic Echocardiogram (TTE)|OTHER: Saline/Air Mixture|OTHER: Saline/Blood Mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Probiotic Supplement on Bowel Function
Status: TERMINATED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Probiotic supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tailored Written Lifestyle Feedback in Colorectal Cancer Screening
Status: COMPLETED
Conditions: Lifestyle|Diet Habit|Smoking Cessation|Physical Activity|Alcohol Drinking|Body Weight
Interventions: BEHAVIORAL: Individually tailored lifestyle feedback|BEHAVIORAL: Standard leaflet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: tDCS Effects on Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain|Chronic Pain
Interventions: DEVICE: sham-tDCS + back school|DEVICE: real-tDCS + back school
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT