pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Bruton's Tyrosine Kinase (BTK) Inhibitor, Ibrutinib, in Patients With Newly Diagnosed or Refractory/Recurrent Primary Central Nervous System Lymphoma (PCNSL) and Refractory/Recurrent Secondary Central Nervous System Lymphoma (SCNSL)
Status: RECRUITING
Conditions: Adult Patients With Newly Diagnosed or Relapsed or Refractory Primary Central Nervous System Lymphoma (PCNSL)|Or Relapsed or Refractory Secondary Central Nervous System Lymphoma (SCNSL)
Interventions: DRUG: Ibrutinib|DRUG: HD- Methotrexate (MTX)|DRUG: Rituximab + HD- Methotrexate (MTX)|DRUG: procarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LEPU Renal Denervation System for Resistant Hypertension
Status: COMPLETED
Conditions: Hypertension|Cardiovascular Diseases|Vascular Diseases
Interventions: DEVICE: LEPU Renal Denervation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Anti-Inflammatory Effects of Colgate Total® During an Experimental Gingivitis Model
Status: COMPLETED
Conditions: Gingivitis
Interventions: OTHER: Toothpaste without triclosan|OTHER: Triclosan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Daily Adaptive Radiation Therapy: An Individualized Approach for Stage III Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage III Non-small Cell Lung Cancer
Interventions: DEVICE: Adaptive Radiotherapy|DEVICE: Non-Adaptive Radiotherapy|DRUG: Chemotherapy|DRUG: Immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Indication-Based Transfusion of Red Blood Cells in ECMO
Status: RECRUITING
Conditions: Extracorporeal Membrane Oxygenation|Red Blood Cell Transfusion|Organ Failure, Multiple
Interventions: OTHER: Red blood cell transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase 2b Study in Subjects With Alcoholic Hepatitis to Evaluate Safety and Efficacy of DUR-928 Treatment
Status: COMPLETED
Conditions: Alcoholic Hepatitis
Interventions: DRUG: DUR-928 30 mg|DRUG: DUR-928 90 mg|DRUG: Placebo+ Standard of Care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Acupressure on Carpal Tunnel Syndrome in Pregnant Women
Status: NOT_YET_RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Acupressure|OTHER: advices for relieving carpal tunnel syndrome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lower Limb Venous Insufficiency and the Effect of Radiofrequency Treatment Versus Open Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Varicose Veins|Venous Insufficiency
Interventions: PROCEDURE: Radiofrequency ablation|PROCEDURE: High ligation/stripping|DEVICE: Radiofrequency ablation catheter|PROCEDURE: Tumescent anesthesia|PROCEDURE: General anesthesia|DEVICE: Vein stripping catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety/Tolerability of Immunotherapy Combinations in Participants With Triple-Negative Breast Cancer or Gynecologic Malignancies
Status: COMPLETED
Conditions: TNBC - Triple-Negative Breast Cancer|Ovarian Cancer
Interventions: DRUG: Etrumadenant|DRUG: IPI-549|DRUG: Pegylated liposomal doxorubicin (PLD)|DRUG: nanoparticle albumin-bound paclitaxel (NP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Whether Different Combinations of BI 765063, Ezabenlimab, Chemotherapy, Cetuximab, and BI 836880 Help People With Head and Neck Cancer or Liver Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma (HNSCC)
Interventions: DRUG: BI 765063|DRUG: Ezabenlimab|DRUG: BI 836880|DRUG: Cetuximab|OTHER: Investigator´s Choice Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Intravitreal Ranibizumab and Macular Laser Photocoagulation for ME Following Branch Retinal Vein Occlusion (BRVO)
Status: UNKNOWN
Conditions: Branch Retinal Vein Occlusion
Interventions: DRUG: Ranibizumab|PROCEDURE: macular laser photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Outcomes During MRI Sedation With Midazolam-dexmedetomidine Versus Ketamine-dexmedetomidine
Status: TERMINATED
Conditions: Sedation
Interventions: DRUG: Ketamine|DRUG: Midazolam|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dermacyd Breeze Pocket BR (Lactic Acid) - Acceptability
Status: COMPLETED
Conditions: Hygiene
Interventions: DRUG: Dermacyd Breeze Pocket BR (Lactic Acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Durvalumab (MEDI4736) (Anti-PD-L1) and Trametinib (MEKi) in MSS Metastatic Colon Cancer
Status: COMPLETED
Conditions: Malignant Neoplasms of Digestive Organs|Colorectal Cancer|Colon Cancer
Interventions: DRUG: Durvalumab|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Typhoid Conjugate Vaccine (Vi-TCV) Among Children Age 9 Months Through 12 Years in Blantyre, Malawi
Status: ACTIVE_NOT_RECRUITING
Conditions: Typhoid
Interventions: BIOLOGICAL: Vi-Typhoid Conjugate Vaccine (Vi-TCV)|BIOLOGICAL: Meningococcal A Conjugate Vaccine (MCV-A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Resistance Training in Water Combined With Land on Starting and Turning ,12-weeks Resistance Training
Status: COMPLETED
Conditions: Resistance, APC
Interventions: OTHER: Resistance training that combines water and land
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nabilone in Cannabis Users With PTSD
Status: TERMINATED
Conditions: Cannabis|Post Traumatic Stress Disorder
Interventions: DRUG: Nabilone|DRUG: Cannabis|DRUG: Propranolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Inhaled Technosphere Insulin in Subjects With Diabetes Mellitus and Asthma
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Asthma
Interventions: DRUG: Technosphere Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the H1-coil Deep TMS in the Treatment of Negative Symptoms and Cognitive Deficit in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DEVICE: deep TMS H-coil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Augmented Reality and Repetitive Transcranial Magnetic Stimulation
Status: RECRUITING
Conditions: Stroke
Interventions: BEHAVIORAL: rTMS and AR|BEHAVIORAL: Sham rTMS and AR|BEHAVIORAL: AR|BEHAVIORAL: Conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Impact of Apremilast on Magnetic Resonance Imaging (MRI) Outcomes in Adults With Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: Apremilast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/IB Trial of MEK162 in Combination With Erlotinib in NSCLC Harboring KRAS or EGFR Mutation
Status: COMPLETED
Conditions: Lung Cancer|Non-Small Cell Lung Cancer
Interventions: DRUG: MEK162|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioactive Split Thickness Skin Allograft Versus Standard of Care in the Treatment of Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot|Ulcer Foot
Interventions: OTHER: Human split thickness skin allograft|OTHER: Additional Outer Dressing Applicaiton|OTHER: Offloading|OTHER: Fibracol Wound Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gas Supply, Demand and Middle Ear Gas Balance -- Diagnosis of Eustachian Tube Dysfunction
Status: TERMINATED
Conditions: Eustachian Tube Dysfunction
Interventions: OTHER: ET Stress test|OTHER: Sonotubometry|OTHER: Forced Response Test (FRT)|OTHER: Inflation Deflation Test (IDT)|OTHER: Maneuver Sequence|OTHER: 9-Step Test|OTHER: Tubomanometry|OTHER: Videoendoscopic assessment of ETF|OTHER: Pressure chamber ET test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tolerance to a New Free Amino Acid-based Formula in Children With IgE or Non-IgE-mediated Cow's Milk Allergy
Status: COMPLETED
Conditions: Cow's Milk Allergy
Interventions: DIETARY_SUPPLEMENT: tolerance to a new aminoacid based formula|DIETARY_SUPPLEMENT: Amino acid formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MY008211A in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)
Status: RECRUITING
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: MY008211A tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pneumococcal Protein Vaccine Safety and Immunogenicity Trial
Status: COMPLETED
Conditions: Adverse Effects
Interventions: DRUG: Pneumococcal protein vaccine|DRUG: Pneumococcal protein vaccine|DRUG: Pneumococcal protein vaccine|DRUG: Pneumococcal protein vaccine|DRUG: Pneumococcal protein vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Participants With Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-585/KEYNOTE-585)
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer|Gastroesophageal Junction Cancer
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Placebo|DRUG: Cisplatin|DRUG: Capecitabine|DRUG: 5-fluorouracil|DRUG: Docetaxel|DRUG: Oxaliplatin|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional and Sexual Outcomes After Laparoscopic Ventral Mesh Rectopexy for Complex Rectocele
Status: COMPLETED
Conditions: Rectocele|Obstructive Defecation Syndrome
Interventions: PROCEDURE: laparoscopic ventral mesh rectopexy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise Training in Chronic Obstructive Pulmonary Disease Versus Alpha-1-Antitrypsin-deficiency-patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Alpha-1-antitrypsin-deficiency
Interventions: PROCEDURE: exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Volume Parameters vs Flow Parameters in Assessment of Reversibility in Chronic Obstructive Pulmonary Disease
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DIAGNOSTIC_TEST: Whole body plethysmography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: PEMF vs Laser for Stress Urinary Incontinence
Status: RECRUITING
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: Pulsed Electromagnetic Field Therapy|DEVICE: Laser Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: T-Cell Depletion and Stem Cell Transplant for Immune Deficiencies and Histiocytic Disorders
Status: TERMINATED
Conditions: Hemophagocytic Lymphohistiocytosis|X-Linked Lymphoproliferative Disorders|Chediak-Higashi Syndrome|Griscelli Syndrome|Immunologic Diseases|Langerhans-Cell Histiocytosis|Hematologic Diseases
Interventions: PROCEDURE: Stem Cell Transplant|DRUG: Myeloablative conditioning regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kinesio Taping Effects on Knee Extension Force Among Soccer Players
Status: COMPLETED
Conditions: Kinesio Taping Effects on Knee Extension Force
Interventions: DEVICE: Kinesio Taping|DEVICE: Placebo Tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pectoralis and Serratus Nerve Blocks for Mastectomy: a Prospective, Randomized, Single-blind Trial
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: sevoflurane and fentanil|DRUG: sevoflurane and fentanil plus PECS II block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Foster Efficacy Maintenance and Reliever Versus Foster Maintenance + Salbutamol Reliever in Asthmatics
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Ventolin|DRUG: beclometasone /formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ib Study of Erlotinib Prior to Surgery in Patients With Head and Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Head and Neck Carcinoma|Recurrent Salivary Gland Carcinoma|Recurrent Skin Carcinoma|Skin Squamous Cell Carcinoma
Interventions: DRUG: Erlotinib Hydrochloride|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Prevent Postoperative Urinary Retention
Status: RECRUITING
Conditions: Urinary Retention|Inguinal Hernia
Interventions: DRUG: TAMSULOSIN Mepha Ret Depocaps 0.4 mg|DRUG: Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Increase Psychological Well-being by the Implementation of Forgiveness Education
Status: COMPLETED
Conditions: Anger|Depressive Symptoms|Anxiety
Interventions: OTHER: forgiveness education intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Luteal-Phase GnRH Agonist Administration in Frozen-Thawed IVF Embryo Transfer Cycles
Status: UNKNOWN
Conditions: Pregnancy Rate
Interventions: DRUG: Decapeptyl 0.1 mg after embryo transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inspiratory and Calf Muscles Training in Patients With Leg Lymphedema
Status: NOT_YET_RECRUITING
Conditions: Lymphedema of Leg|Lymphedema|Exercise
Interventions: OTHER: Compression Therapy|OTHER: Inspiratory muscle training|OTHER: Calf muscle exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Measurement of Exhaled Nitric Oxide (NO) and Bronchial Provocation Test With Mannitol as a Predictor of Response to Inhaled Corticosteroids in Chronic Cough
Status: COMPLETED
Conditions: Cough|Bronchial Hyperreactivity
Interventions: PROCEDURE: bronchial provocation test with mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Salt Solution Immersion Bath on Cancer in Vivo.
Status: WITHDRAWN
Conditions: Cancer
Interventions: DRUG: 25% Hypertonic Saline Bath|OTHER: 0.9% Isotonic Saline Bath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Probiotics for Birch Pollen Allergy
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: BIOLOGICAL: Lactobacillus acidophilus and Bifidobacterium lactis|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proactive Outreach and Shared Decision Making in Improving Lung Cancer Screening Rates in Primary Care Patients
Status: COMPLETED
Conditions: Lung Cancer
Interventions: OTHER: Best Practice|BEHAVIORAL: Cancer Educational Materials|OTHER: Behavioral, Psychological or Informational Intervention|OTHER: Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: CARE Corrections: Technology for Jail HIV/HCV Testing, Linkage, and Care (TLC)
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: DEVICE: Intervention Arm (computer-based CARE+ Corrections tool)|OTHER: Educational video on opiate overdose prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study on Autologous Osteoblastic Cells Implantation in Hypotrophic Non-Union Fractures
Status: TERMINATED
Conditions: Long Bone Non-Union
Interventions: DRUG: PREOB® Implantation|PROCEDURE: Bone Autograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid-free Anesthesia in Laparoscopic Cholecystectomies
Status: RECRUITING
Conditions: Pain, Postoperative|Pain, Acute|Pain, Chronic|Cholecystectomy|Ketamine|Dexmedetomidine|Lidocaine|Central Nervous System Depressants|Analgesia|Analgesics|Analgesic Non-narcotic
Interventions: DRUG: ketamine-lidocaine-dexmedetomidine|DRUG: fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of YM150 in Patients With Knee Replacement Surgery
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee
Interventions: DRUG: YM150|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of Multifocal Intraocular Lens: OPTIVIS.TM
Status: COMPLETED
Conditions: Cataract Senile|Lenses, Intraocular
Interventions: DEVICE: OptiVis, Aaren Scientific|DEVICE: Monofocal IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Octreotide LAR in Prevention of Chemotherapy-induced Diarrhea
Status: COMPLETED
Conditions: Chemotherapy-induced Diarrhea
Interventions: DRUG: Octreotide Long Acting Release|OTHER: Standard Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy, Safety, and Immunogenicity of Subcutaneous DMB-3115 Versus Stelara® in Patients With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Moderate to Severe Chronic Plaque Psoriasis
Interventions: DRUG: DMB-3115|DRUG: Stelara
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Value of Chemokine Receptor CXCR4 Imaging for Diagnosis and Prognostic Evaluation in Lymphoproliferative Diseases
Status: RECRUITING
Conditions: Lymphoma|Multiple Myeloma|Leukemia
Interventions: DRUG: 68Ga-Pentixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lexical Priming by Music in Alzheimer's Disease and Healthy Aging
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: OTHER: Exposure to familiar songs|OTHER: Music Experience Questionnaire|OTHER: Implicit tasks memory|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Single Dose Mass Balance Study With [14C]Iruplinalkib (WX-0593) In Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [14C]Iruplinalkib (WX-0593)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Insulin Sensitivity Study in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ALKS 3831|DRUG: Olanzapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Exercise and Enteral Nutrition on Survival
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer|Nutrition Related Cancer|Sarcopenia
Interventions: BEHAVIORAL: Exercise Intervention|DIETARY_SUPPLEMENT: Nutrition Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Ivermectin Cream 1% in Treatment of Moderate to Severe Facial Rosacea
Status: COMPLETED
Conditions: Facial Rosacea
Interventions: DRUG: Soolantra® Ivermectin cream 1%|DRUG: Ivermectin cream 1%|DRUG: Placebo for Ivermectin cream 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CACOLAC : Citrulline Administration in the Hospital Patient in Intensive Care for COVID-19 Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: ARDS Secondary to COVID-19 Pneumonia
Interventions: DIETARY_SUPPLEMENT: L-citrulline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mirvetuximab Soravtansine (IMGN853), in Folate Receptor Alpha (FRα) High Recurrent Ovarian Cancer
Status: RECRUITING
Conditions: Recurrent Epithelial Ovarian, Fallopian or Peritoneal Carcinoma
Interventions: DRUG: Carboplatin|DRUG: Pegylated liposomal doxorubicin (PLD)|DRUG: Gemcitabine|DRUG: Paclitaxel|DRUG: Mirvetuximab Soravtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Study of SV-BR-1-GM With Retifanlimab
Status: ENROLLING_BY_INVITATION
Conditions: Breast Cancer|Breast Neoplasm|Metastatic Breast Cancer|Breast Cancer Metastatic
Interventions: BIOLOGICAL: SV-BR-1-GM|DRUG: Low dose cyclophosphamide|DRUG: Interferon Inoculation|DRUG: retifanlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Online CBT for GAD Compared to Pharmaceutical Interventions
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: SSRIs/SNRIs (Selective Serotonin Reuptake Inhibitors/ Serotonin and Norepinephrine Reuptake Inhibitors)|BEHAVIORAL: Electronic Cognitive Behavioural Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intermittent Rifampicin on Raltegravir
Status: COMPLETED
Conditions: HIV|Tuberculosis
Interventions: DRUG: Raltegravir|DRUG: Rifampicin|DRUG: Raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Multicenter, Randomized Trial to Evaluate the Safety and Immunogenicity of a Recombinant Vaccinia-HIV Envelope Vaccine (HIVAC-1e) in Combination With a Panel of Subunit Recombinant HIV Envelope Vaccines in Vaccinia-Naive Individuals
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: gp160 Vaccine (Immuno-AG)|BIOLOGICAL: rgp120/HIV-1IIIB|BIOLOGICAL: rgp120/HIV-1MN|BIOLOGICAL: rgp120/HIV-1 SF-2|BIOLOGICAL: HIVAC-1e
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Triheptanoin (C7 Oil), a Food Supplement, for Glucose Transporter Type I Deficiency (G1D)
Status: WITHDRAWN
Conditions: Glucose Transporter Type 1 Deficiency Syndrome|Glut1 Deficiency Syndrome
Interventions: DRUG: Triheptanoin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Short Term Amiodarone Treatment After Catheter Ablation for Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Catheter ablation|DRUG: Amiodarone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inferior Vena Cava Collapsibility Index Guide for Preoperative Fluid Therapy in Preeclampsia
Status: RECRUITING
Conditions: Pre-Eclampsia|Hypotension|Fluid Overload
Interventions: OTHER: fluid therapy, 300 ml of crystalloid Ringer's solution.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Perfluorohexyloctane (NovaTears) on Tear Film Thickness in Patients With Mild to Moderate Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DEVICE: NovaTears®|DEVICE: Hydrabak®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of JVS-100 Administered to Adults With Ischemic Heart Failure
Status: UNKNOWN
Conditions: Ischemic Heart Failure
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: 30 mg dose of JVS-100|BIOLOGICAL: 45 mg dose of JVS-100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bryophyllum Versus Placebo for Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Bryophyllum pinnatum, Placebo in form of Lactose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Human Empowerment Aging and Disability (HEAD): New Technologies for Neurorehabilitation
Status: COMPLETED
Conditions: Rehabilitation|Technology|Telerehabilitation|Nervous System Diseases
Interventions: OTHER: Multimedial Rehabilitation|OTHER: Usual care program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bispectral Index Under Propofol Anesthesia in Children : a Study Between TIVA and TCI
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Propofol : TCI Schnider|DRUG: Propofol : TCI Kataria|DRUG: Propofol : TIVA|DEVICE: EEG Monitoring|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Novel Multisensory-Rhythmic Intervention in Geriatric Rehabilitation
Status: RECRUITING
Conditions: Virtual Reality|Hand Mirror|Geriatric|Kinesiology, Applied
Interventions: OTHER: virtual-reality based rhythmic skill training|OTHER: rhythmic skill training with visual feedback|OTHER: strengthening group|OTHER: breathing and muscle relaxation exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIV-1 Infected Patients, Phase II Trial, Dual Combination Doravirine/Raltegravir Open Label
Status: RECRUITING
Conditions: HIV Infections
Interventions: DRUG: DORAVIRINE 100 MG [Pifeltro]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individually Tailored Lighting System to Improve Sleep in Older Adults
Status: COMPLETED
Conditions: Sleep Disturbances
Interventions: OTHER: Blue light|OTHER: Red light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Enhanced Interactive Text Messages and Phone Instruction on the Quality of Bowel Preparation for Colonoscopy.
Status: UNKNOWN
Conditions: Colon Polyp|Colon Neoplasm
Interventions: OTHER: Enhanced bowel preparation instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pilot Study to Determine Effects of the Btk Inhibitor PCI-32765 on Leukemia Cell Kinetics and Trafficking, Using Heavy Water Labeling in Subjects With CLL and SLL
Status: COMPLETED
Conditions: Leukemia
Interventions: OTHER: Heavy Water (2H2O)|DRUG: PCI-32765
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protective Effect of Intraoperative Parathyroid Gland Auxiliary Recognition System in Thyroid Malignant Tumor Operation
Status: UNKNOWN
Conditions: Parathyroid|Intraoperative Monitoring|Thyroid Cancer
Interventions: DEVICE: Intraoperative parathyroid gland auxiliary recognition system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Naproxen-codeine, Naproxen+Dexamethasone, and Naproxen on Myofascial Pain
Status: COMPLETED
Conditions: Temporomandibular Disorder
Interventions: DRUG: naproxen sodium+codeine phosphate, naproxen sodium+dexamethasone, naproxen sodium, paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of SFF on Glucose and Insulin Responses
Status: COMPLETED
Conditions: Postprandial Glycemic Response
Interventions: DIETARY_SUPPLEMENT: SFF|DIETARY_SUPPLEMENT: Glucose|DIETARY_SUPPLEMENT: SFF chocolate chips|DIETARY_SUPPLEMENT: Regular chocolate chips
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Pembrolizumab, Capecitabine, and Bevacizumab in Treating Patients With Microsatellite Stable Colorectal Cancer That Is Locally Advanced, Metastatic, or Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Microsatellite Stable|Mismatch Repair Protein Proficient|Stage III Colorectal Cancer AJCC v7|Stage IIIB Colorectal Cancer AJCC v7|Stage IIIC Colorectal Cancer AJCC v7|Stage IV Colorectal Cancer AJCC v7|Stage IVA Colorectal Cancer AJCC v7|Stage IVB Colorectal Cancer AJCC v7
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Capecitabine|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleepiz One+ Versus Capnography and Electrocardiography
Status: COMPLETED
Conditions: COPD|Hypertension|Sleep Apnea|Asthma|Heart Diseases|Respiratory Disease
Interventions: DEVICE: Sleepiz One+
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Trial of the Inactivated Influenza Vaccine (0.25ml Formulation for Pediatric Use)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza Split Vaccine|BIOLOGICAL: Inactivated Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intra Uterine Device Insertion in Nulliparous Women
Status: TERMINATED
Conditions: Contraception
Interventions: DRUG: Misoprostol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glucagon Ready-to-Use (RTU) for Prevention of Exercise-Induced Hypoglycemia During Aerobic Exercise in Adults With T1D
Status: COMPLETED
Conditions: Hypoglycemia
Interventions: DRUG: Glucagon RTU Injection With Insulin Pump Reduction|OTHER: Vehicle for Glucagon RTU Injection With Insulin Pump Reduction|DRUG: Glugaon RTU Injection Without Insulin Pump Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prehabilitation for Stage IIIC-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Patients
Status: RECRUITING
Conditions: Advanced Ovarian Carcinoma|Stage IIIC Fallopian Tube Cancer AJCC v8|Stage IIIC Ovarian Cancer AJCC v8|Stage IIIC Primary Peritoneal Cancer AJCC v8|Stage IV Fallopian Tube Cancer AJCC v8|Stage IV Ovarian Cancer AJCC v8|Stage IV Primary Peritoneal Cancer AJCC v8
Interventions: BEHAVIORAL: Behavioral Counseling|DIETARY_SUPPLEMENT: Nutritional Supplement Drink|OTHER: Physical Activity|OTHER: Survey Administration|PROCEDURE: Computed Tomography|PROCEDURE: Biospecimen Collection|BEHAVIORAL: Health Education|OTHER: Medical Device Usage and Evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of a Multispecies Probiotic on Hypersensitivity in Irritable Bowel Syndrome (IBS) Patients
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Hypersensitivity
Interventions: DIETARY_SUPPLEMENT: multispecies probiotic (Ecologic 801)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Describe the Effectiveness of Arrhythmia Analysis Software for Screening of Sinus Rhythm, Atrial Fibrillation and Premature Beats in light-and Dark Skin Tone Patients
Status: RECRUITING
Conditions: Arrhythmia, Cardiac
Interventions: DEVICE: Arrhythmia Analysis Software (software) which runs on a mobile application (Huawei Phone) and uses input from a wearable device (smart watch or smart band).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ergon Technique Versus PNF Stretching on Hamstring Flexibility in Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: ERGON Technique|OTHER: Proprioceptive Neuromuscular Facilitation (PNF) stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Responses in Infants After Acellular Pertussis Vaccination During Pregnancy in Thailand
Status: COMPLETED
Conditions: Pertussis
Interventions: BIOLOGICAL: Boostrix|BIOLOGICAL: Infanrix hexa|BIOLOGICAL: Quinvaxem|BIOLOGICAL: OPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of a Novel and Simplified Technique for Intrauterine Contraceptive Devices Insertion: a Prospective Cohort Study
Status: COMPLETED
Conditions: Contraception
Interventions: OTHER: IUD|OTHER: Uterine sounding|RADIATION: Transvaginal ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Multi-Institutional Phase II Study of Cyclophosphamide, Paclitaxel, Cisplatin With G-CSF for Patients With Newly Diagnosed Advanced Stage Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasm
Interventions: DRUG: Cyclophosphamide|DRUG: Paclitaxel|DRUG: Cisplatin|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Combined Use of a Respiratory Broad Panel mPCR and Procalcitonin to Reduce Duration of Antibiotics Exposure in Patients With Severe Community-Acquired Pneumonia
Status: COMPLETED
Conditions: Community-acquired Pneumonia
Interventions: DEVICE: Antibiotic therapy according to the result of mPCR (device)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Exercise in Adults With Mild Memory Problems
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Cognitive Decline|Memory Impairment
Interventions: BEHAVIORAL: Aerobic exercise|BEHAVIORAL: Stretching/balance/range of motion exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Immunogenicity of a Live Attenuated Virus Vaccine to Prevent Influenza H3N2v Disease
Status: TERMINATED
Conditions: Influenza
Interventions: BIOLOGICAL: H3N2v MN 2010/AA ca live attenuated influenza vaccine (LAIV)|BIOLOGICAL: H3N2v inactivated subvirion influenza vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Modafinil for Treatment of Fatigue in ALS Patients
Status: COMPLETED
Conditions: Fatigue
Interventions: DRUG: Modafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Canadian, Multi-centre, Observational Registry to Study Adherence and Long Term Outcomes of Therapy in Pediatric Subjects Using SAIZEN® Via Easypod™ Auto-injector for Growth Hormone Treatment
Status: COMPLETED
Conditions: Growth Disorders
Interventions: DEVICE: Easypod™
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Naïve HIV POC Monotherapy Trial
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: RDEA806 400 mg|DRUG: Placebo|DRUG: RDEA806 1000 mg|DRUG: RDEA806 600 mg|DRUG: RDEA806 800 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Benefit of Hydroxychloroquine in COVID-19 Cases With Mild to Moderate Symptoms and in Healthcare Workers With High Exposure Risk
Status: WITHDRAWN
Conditions: COVID-19
Interventions: DRUG: Hydroxychloroquine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clopidogrel Versus Aspirin MOnotherapy After 1- to 3-month of Dual-antiplatelet thErapy Following Zotarolimus-eluting Onyx Stents Implantation; C-MODE Trial
Status: RECRUITING
Conditions: Ischemic Heart Disease
Interventions: DRUG: Clopidogrel monotherapy|DRUG: Aspirin monotherapy|DEVICE: zotarolimus-eluting stent (Resolute Onyx ®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-in-Human Study to Learn How Well a Bi-Layer Calcium Carbonate Antacid Tablet Works Compared to a Standard, Non-Layered Calcium Carbonate Tablet in Healthy Male Participants
Status: COMPLETED
Conditions: Heartburn|Indigestion|Stomach Acid Related Symptoms|Nocturnal Stomach Acid Related Symptoms|Healthy Volunteers
Interventions: DRUG: bi-layer calcium carbonate tablet (BAY1180654)|DRUG: Immediate release calcium carbonate tablet (BAY1180654)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: "Colorectal Leakage App" for Early Detection of Anastomotic Leakage After Colorectal Surgeries
Status: RECRUITING
Conditions: Anastomotic Leak Large Intestine|Anastomotic Leak Rectum
Interventions: DIAGNOSTIC_TEST: "Colorectal Leakage App"
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment's Duration of Acute Uncomplicated Pyelonephritis
Status: COMPLETED
Conditions: Urinary Tract Infection|Fever
Interventions: DRUG: levofloxacin, ciprofloxacin and ofloxacin (fluoroquinolones)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omental Islet Transplant
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: PROCEDURE: Omental Islet transplant|DRUG: Anti-Thymocyte Globulin|DRUG: Mycophenolate mofetil|DRUG: Tacrolimus|DRUG: Etanercept|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Pharmacoscintigraphic Comparison of TobrAir® 6.0 With TOBI® and TOBI® Podhaler™
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tobramycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zero Sodium Peritoneal Dialysate Protocol Pilot Study
Status: COMPLETED
Conditions: Potential Applications for Heart Failure|Volume Overload
Interventions: DRUG: Two-hour dwell with 10% dextrose in sterile water|DRUG: Two-hour dwell with Dianeal Low-Calcium with 4.25% Dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: AGN-151586 Dose-Ranging Study for Treatment of Glabellar Lines
Status: COMPLETED
Conditions: Glabellar Lines
Interventions: DRUG: AGN-151586|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Anlotinib, Irinotecan and Temozolomide in the Treatment of Refractory or Recurrent Neuroblastoma in Children: an Open, Single Arm, Single Center, Phase II Clinical Study
Status: UNKNOWN
Conditions: Refractory or Recurrent Neuroblastoma in Children
Interventions: DRUG: Anlotinib and irinotecan combined with temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: N-acetylcysteine to Reduce Ischemia/Reperfusion Injury in Liver Resection
Status: COMPLETED
Conditions: Hepatectomy|Reperfusion Injury
Interventions: DRUG: Acetylcysteine (NAC)|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Real-life Current Standards of Care in Patients With Relapsed and/or Refractory Multiple Myeloma Who Received at Least 3 Prior Lines of Therapy Including Proteasome Inhibitor (PI), Immunomodulatory Drug (IMID), and Cluster of Differentiation 38 (CD38) Monoclonal Antibody Treatment
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Oral DHEA Therapy for Postmenopausal Women on Sexual Function, Wellbeing and Vasomotor Symptoms
Status: COMPLETED
Conditions: Quality of Life|Menopausal Syndrome|Libido Disorder
Interventions: DRUG: dehydroepiandrosterone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conditioning Regimen in Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation
Status: TERMINATED
Conditions: Renal Cell Cancer
Interventions: DRUG: Fludarabine|DRUG: Melphalan|DRUG: Cyclophosphamide|PROCEDURE: Stem Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety Effects Using Mikelan® LA Ophthalmic Solution (OS) 2% Versus Timoptol® XE Ophthalmic Solution (OS) 0.5% in Ocular Hypertension Patients
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: carteolol (Mikelan), timolol (Timoptol), latanoprost (Xalatan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT