pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: MDSC Clinical Assay in Finding and Monitoring Cancer Cells in Blood and Urine Samples From Patients With or Without Localized or Metastatic Bladder Cancer
Status: TERMINATED
Conditions: No Evidence of Disease|Stage II Bladder Cancer|Stage III Bladder Cancer|Stage IVA Bladder Cancer|Stage IVB Bladder Cancer
Interventions: OTHER: Cytology Specimen Collection Procedure|OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiation Therapy in Treating Patients With Hepatocellular Carcinoma, Cholangiocarcinoma, or Liver Metastasis Who Have Impaired Liver Function
Status: ACTIVE_NOT_RECRUITING
Conditions: Cholangiocarcinoma|Cirrhosis|Hepatocellular Carcinoma|Metastatic Malignant Neoplasm in the Liver
Interventions: OTHER: Laboratory Biomarker Analysis|PROCEDURE: Magnetic Resonance Imaging|RADIATION: Radiation Therapy|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Importance of Positive Expiratory Pressure Associated With the In-exsufflator in ALS Patients
Status: NOT_YET_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis ALS7
Interventions: DEVICE: MI-E with PEP function activated during the pause|DEVICE: MI-E without PEP function activated during the pause
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: TWILIGHT Study: Effect of Light Exposure During Acute Rehabilitation on Sleep After TBI
Status: COMPLETED
Conditions: Traumatic Brain Injury|TBI|Sleep
Interventions: DEVICE: Bright White Light (BWL)|DEVICE: Red Light (RL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study of Isavuconazole and Digoxin
Status: COMPLETED
Conditions: Pharmacokinetics of Isavuconazole|Pharmacokinetics of Digoxin|Healthy Volunteers
Interventions: DRUG: Isavuconazole|DRUG: digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Endoscopic Combined Intrarenal Surgery vs. Percutaneous Nephrolithotomy for Treatment of Staghorn Calculi
Status: RECRUITING
Conditions: Urinary Calculi
Interventions: PROCEDURE: Combined Intrarenal Surgery and percutaneous nephrolithotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcranial Direct Current Stimulation on Reward Learning in Subclinical Depression.
Status: UNKNOWN
Conditions: Dysphoria
Interventions: DEVICE: Transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of the Efficacy and Safety of SP-624 in the Treatment of Adults With Major Depressive Disorder
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: SP-624|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Combination of Mycophenolate Mofetil and Corticosteroid in Advanced IgA Nephropathy
Status: UNKNOWN
Conditions: IgA Nephropathy
Interventions: DRUG: Mycophenolate Mofetil|DRUG: ACE inhibitor|DRUG: Corticosteroid|DRUG: ARB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Hypertrophic Scars Using Fractional Laser and Fractional Laser-assisted Topical Corticosteroid Delivery
Status: COMPLETED
Conditions: Hypertrophic Scars
Interventions: DRUG: 0.05% Clobetasol propionate|DRUG: Petrolatum gel|DEVICE: Fractional Erbium:Yag (2,940-nm) laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of β-hydroxy β-methyl Butyrate (HMB)Supplementation on Post-operative Muscle Mass and Function in Female Athletes
Status: RECRUITING
Conditions: Atrophy
Interventions: DRUG: CaHMB (Dietary supplement, not Drug)|DIETARY_SUPPLEMENT: CaLa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Online Obesity Treatment in Primary Care (Rhode Island, USA)
Status: UNKNOWN
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Training to Identify Eligible Patients and Direct them to Online Obesity Treatment Program|BEHAVIORAL: Training to Motivate and Support Patients' Weight Loss|BEHAVIORAL: Online Behavioral Weight Loss Intervention|BEHAVIORAL: Control Intervention for Weight Loss Maintenance and Weight Gain Prevention|BEHAVIORAL: Monthly Lessons and Feedback Intervention for Weight Loss Maintenance and Weight Gain Prevention|BEHAVIORAL: Refresher Courses for Weight Loss Maintenance and Weight Gain Prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Baricitinib (LY3009104) in Participants With Systemic Lupus Erythematosus
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Baricitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Rituximab, Chidamide, Zanubrutinib-induced and CHOP Therapy
Status: RECRUITING
Conditions: Double Express Diffuse Large B-cell Lymphoma
Interventions: DRUG: Rituximab, Chidamide, Zanubrutinib-induced and CHOP Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation Study of Covariates Model (VaSCoM) for Propofol
Status: COMPLETED
Conditions: Target Controlled Infusion of Propofol
Interventions: DRUG: Propofol|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Comparative Clinical Trial to Evaluate Efficacy and Safety of BCD-055 and Remicade® in Patients With Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: BIOLOGICAL: BCD-055|BIOLOGICAL: Remicade®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity, Tolerability and Safety of One or Two Doses of an Adjuvanted Swine-origin A H1N1 Influenza Vaccine in Healthy Subjects 18 or More Years of Age Both Vaccinated and Not Yet Vaccinated Against Seasonal Influenza 2009/10
Status: COMPLETED
Conditions: Pandemic Influenza Disease
Interventions: BIOLOGICAL: Monovalent A/H1N1 influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Reminerlization Potential of Innovative Biomimetic Material in Caries White Spot Lesions
Status: UNKNOWN
Conditions: White Spot Lesion of Tooth
Interventions: DRUG: Clinpro Tooth Creme|DRUG: GC tooth mousse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ASP2215 (Gilteritinib) Combined With Atezolizumab in Patients With Relapsed or Treatment Refractory FMS-like Tyrosine Kinase (FLT3) Mutated Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia (AML)|Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) Mutation
Interventions: DRUG: gilteritinib|DRUG: atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biocontainment Device for Aerosol Generating Procedures
Status: COMPLETED
Conditions: Protective Device (Physical Object)|Aerosol Disease|Droplet Spread
Interventions: DEVICE: Biocontainment Device For Aerosol Generating Procedures (Biobox)|DEVICE: Control for aerosol generating procedures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Crossover Study to Evaluate the Efficacy, Safety and Tolerability of Different Doses of Indacaterol in Patients With Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Indacaterol 27.5 mcg|DRUG: Indacaterol 37.5|DRUG: Indacaterol 55 mcg|DRUG: Indacaterol 75 mcg|DRUG: Indacaterol 150 mcg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Mild Vascular Cognitive Impairment With Yangxue Qingnao Pill
Status: COMPLETED
Conditions: Cerebrovascular Diseases
Interventions: DRUG: Yangxue Qingnao pill|DRUG: Hydergotoxine mesylate tablets|OTHER: blank control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sym021 Monotherapy, in Combination With Sym022 or Sym023, and in Combination With Both Sym022 and Sym023 in Patients With Advanced Solid Tumor Malignancies or Lymphomas
Status: COMPLETED
Conditions: Metastatic Cancer|Solid Tumor|Lymphoma
Interventions: DRUG: Sym021|DRUG: Sym022|DRUG: Sym023
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AIN457 Regimen Finding Extension Study in Participants With Moderate to Severe Psoriasis
Status: COMPLETED
Conditions: Plaque-type Psoriasis
Interventions: DRUG: AIN457|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Tolerance of Remicade in the Treatment of Active Ankylosing Spondylitis (Study P04042)(COMPLETED)
Status: COMPLETED
Conditions: Spondylitis, Ankylosing
Interventions: BIOLOGICAL: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Single-center, Single-arm, Open Label Trial of Vismodegib in Patients With Keratocystic Odontogenic Tumors
Status: COMPLETED
Conditions: Keratocystic Odontogenic Tumor
Interventions: DRUG: vismodegib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two-cohort Study of Niraparib and Dostarlimab Plus (Chemo)RadIotherapy in Locally-Advanced Head and Neck Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Dostarlimab|DRUG: Niraparib|DRUG: cisplatin plus radiotherapy|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Nivolumab and Ipilimumab in Untreated Participants With Stage 3 Non-small Cell Lung Cancer (NSCLC) That is Unable or Not Planned to be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer (NSCLC)
Interventions: BIOLOGICAL: nivolumab|BIOLOGICAL: ipilimumab|BIOLOGICAL: durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Avastin and Doxil in Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Doxil|DRUG: Bevacizumab (Avastin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib in Combination With Venetoclax or Obinutuzumab for the Treatment of Treatment-naive Chronic Lymphocytic Leukemia
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Acalabrutinib|BIOLOGICAL: Obinutuzumab|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PMCF Study on the Safety, Performance and Clinical Benefits Data of the Anatomical Shoulder 2.0 Fracture System
Status: RECRUITING
Conditions: Proximal Humerus Fracture|Posttraumatic Arthrosis After Humeral Head Fracture|Posttraumatic Necrosis of the Humeral Head
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Neupro on Cardiovascular Observations in Patients With Restless Legs Syndrome
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: Rotigotine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Administration of Romidepsin and 3BNC117 in Treatment-naïve HIV Patients Starting ART
Status: UNKNOWN
Conditions: Hiv
Interventions: DRUG: Romidepsin|DRUG: 3BNC117|DRUG: Antiretrovirals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alisertib and Romidepsin in Treating Patients With Relapsed or Refractory B-Cell or T-Cell Lymphomas
Status: COMPLETED
Conditions: MYC Positive|Recurrent B-Cell Non-Hodgkin Lymphoma|Recurrent Burkitt Lymphoma|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Follicular Lymphoma|Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements|Recurrent Hodgkin Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Mature T- and NK-Cell Non-Hodgkin Lymphoma|Refractory B-Cell Non-Hodgkin Lymphoma|Refractory Burkitt Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Follicular Lymphoma|Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements|Refractory Hodgkin Lymphoma|Refractory Mantle Cell Lymphoma|Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma
Interventions: DRUG: Alisertib|OTHER: Laboratory Biomarker Analysis|DRUG: Romidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Patient Preference and Satisfaction of Subcutaneous Administration of the Fixed-Dose Combination of Pertuzumab and Trastuzumab in Participants With HER2-Positive Early Breast Cancer
Status: COMPLETED
Conditions: HER2-Positive Early Breast Cancer
Interventions: DRUG: Pertuzumab and Trastuzumab Fixed-Dose Combination for Subcutaneous Administration (PH FDC SC)|DRUG: Pertuzumab IV|DRUG: Trastuzumab IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Optimal XR-Buprenorphine Initiation Points in Jail
Status: WITHDRAWN
Conditions: Opioid Use Disorder
Interventions: DRUG: Extended-Release Buprenorphine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Physiological Effects of Pacing on Catheter Ablation Procedures to Treat Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Pace During 1st Half of Lesion|PROCEDURE: Pace During 2nd Half of Lesion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Kinesiology Taping and Instrument Assisted Soft Tissue Mobilization in Cervicogenic Headache
Status: COMPLETED
Conditions: Headache|Cervical Pain
Interventions: OTHER: kinesiology taping with conventional therapy|OTHER: Instrument assisted soft tissue mobilization with conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interventions for Convergence Insufficiency in Concussed Children
Status: NOT_YET_RECRUITING
Conditions: Concussion|Convergence Insufficiency
Interventions: BEHAVIORAL: Standard Community Concussion Care (SC)|BEHAVIORAL: SC plus Simple Convergence Exercises (SC+)|BEHAVIORAL: SC plus Office-based Vergence/Accommodative Therapy (SC+OBVAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SleepSure: A Trial to Assess the Effects of Eye Masks and Earplugs on Hospital Inpatient Sleep
Status: COMPLETED
Conditions: Sleep
Interventions: DEVICE: Ear plugs|DEVICE: Eye Mask|DRUG: Zopiclone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotic Lozenge on Gingivitis and Periodontitis
Status: COMPLETED
Conditions: Mild and Moderate Chronic Periodontitis
Interventions: DRUG: Probiotic Arm|DRUG: Placebo Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine and Desflurane Consumption
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo|PROCEDURE: Ondansetron|PROCEDURE: fentanyl|PROCEDURE: propofol|PROCEDURE: Atracurium|PROCEDURE: diclofenac sodium|PROCEDURE: desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Bupivacaine Effectiveness and Safety in SABER® Trial
Status: COMPLETED
Conditions: Postoperative Pain|Abdominal Surgery
Interventions: DRUG: SABER-Bupivacaine|DRUG: Bupivacaine HCl|DRUG: SABER-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Initiate Study Evaluating if Mothers Who Are Both Breastfeeding and Pumping in the First Days After Delivery Report Improved Comfort Levels With the New Symphony Program Card
Status: COMPLETED
Conditions: Breast Pumping
Interventions: DEVICE: breast pumping as per SoC but on new software for the pump
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Relacorilant in Combination With Nab-Paclitaxel for Patients With Recurrent Platinum-Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: UNKNOWN
Conditions: Recurrent Ovarian Cancer|Recurrent Fallopian Tube Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: DRUG: Relacorilant, 100mg QD|DRUG: Nab-paclitaxel, 80mg/m^2|DRUG: Nab-paclitaxel, 100mg/m^2|DRUG: Relacorilant, 150mg QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety and Tolerability of PMC-403 in Subjects With Neovascular Age-related Macular Degeneration
Status: RECRUITING
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: PMC-403
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Restrictive and Liberal Transfusion Strategies in Intensive Care
Status: COMPLETED
Conditions: Intensive Care|Blood Transfusion|Anemia
Interventions: BIOLOGICAL: Restrictive RBC Transfusion|BIOLOGICAL: Liberal RBC Transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Personalized Mind-Body Intervention (MBI) for Improving Sleep Among Women Working in Healthcare
Status: RECRUITING
Conditions: Sleep Insufficiency
Interventions: BEHAVIORAL: Personalized Trial ABCCBA|BEHAVIORAL: Personalized Trial CBAABC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Vitamin A Equivalence of Plant Carotenoids in Children
Status: COMPLETED
Conditions: Vitamin A Deficiency
Interventions: DIETARY_SUPPLEMENT: dietary carotenoids|DIETARY_SUPPLEMENT: spinach, rice, and synthetic beta-carotene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: APG-1252 Monotherapy or in Combination With Other Therapeutic Agent in Subjects With Relapsed or Refractory Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: NHL, Adult
Interventions: DRUG: APG-1252|DRUG: Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Caffeine on Ischemic Preconditioning
Status: COMPLETED
Conditions: Caffeine|Ischemic Preconditioning|Ischemia-Reperfusion Injury
Interventions: DRUG: caffeine|DRUG: Technetium-TC99m-labeled Annexin A5|PROCEDURE: ten minutes forearm ischemia|PROCEDURE: ischemic forearm exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: T Cells Expressing a Novel Fully-Human Anti-BCMA CAR for Treating Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Myeloma-Multiple|Myeloma, Plasma-Cell
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: Anti-B Cell Maturation Antigen (BCMA) chimeric antigen receptors (CARs) T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diffusion Weighted-MRI Based Evaluation of the Effectiveness of Endovascular Clamping During Carotid Artery Stenting With the Mo.Ma Device.
Status: COMPLETED
Conditions: Carotid Artery Disease|Stroke Prevention
Interventions: DEVICE: Carotid artery stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Personalized Shared Eye-care Identification of Age-related Macular Degeneration Using Artificial Intelligence and Telemedicine by Matching Optometrist Office-based Sites With Clinical Supervision
Status: NOT_YET_RECRUITING
Conditions: Age-Related Macular Degeneration
Interventions: DEVICE: TopCon Maestro 2 OCT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gastrointestinal Integrity After Naproxen + Rebamipide Versus Naproxen + Placebo
Status: COMPLETED
Conditions: Gastrointestinal Lesions
Interventions: DRUG: Rebamipide effervescent granules|DRUG: Placebo effervescent granules|DRUG: Naproxen tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance
Status: RECRUITING
Conditions: Ascending Aortic Aneurysm Enlargement|Ascending Aorta Aneurysm
Interventions: PROCEDURE: Thoracic Aortic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CNF2024 (BIIB021) HER2- (QD) HER2+ (BIW w/Herceptin) PK/PD Study
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: CNF2024|DRUG: CNF2024 + trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oncolytic Virus Ad-TD-nsIL12 for Primary Pediatric Diffuse Intrinsic Pontine Glioma
Status: RECRUITING
Conditions: Oncolytic Virus|Diffuse Intrinsic Pontine Glioma|Adverse Drug Event
Interventions: BIOLOGICAL: Ad-TD-nsIL12
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panobinostat and Letrozole in Treating Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: letrozole|DRUG: panobinostat|GENETIC: RNA analysis|GENETIC: microarray analysis|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: enzyme-linked immunosorbent assay|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studying the Safety, Efficacy, and Pharmacokinetic Characteristics of BNCT in Patients With Recurrent High-grade Gliomas
Status: RECRUITING
Conditions: Recurrent High-grade Glioma|Recurrent Glioblastoma|Recurrent Anaplastic Astrocytoma|Recurrent Anaplastic Oligodendroglioma
Interventions: RADIATION: 500mg/kg/3hr followed by neutron irradiation to reach maximum brain dose of 9Gy-Eq|RADIATION: 500mg/kg/3hr followed by neutron irradiation to reach maximum brain dose of 11Gy-Eq|RADIATION: 500mg/kg/3hr followed by neutron irradiation to reach maximum brain dose of 13Gy-Eq
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mohs and Immunofluorescence for Malignant Melanoma In Situ
Status: WITHDRAWN
Conditions: Lentigo Maligna|Melanoma In Situ
Interventions: PROCEDURE: H&E|PROCEDURE: IHC MART-1|PROCEDURE: IF MART-1|PROCEDURE: IF cocktail
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Osteoporosis Prevention After Heart Transplant
Status: COMPLETED
Conditions: Osteoporosis|Cardiac Transplantation
Interventions: DRUG: Alendronate|DRUG: Calcitriol|DRUG: Placebo Alendronate|DRUG: Placebo Calcitriol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Bevacizumab and Ixabepilone for Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Non-squamous Non-small Cell Lung Cancer
Interventions: DRUG: ixabepilone|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine if Ibuprofen in Combination With Pseudoephedrine HCl is More Effective Than Each Drug Alone in the Treatment of Nighttime Bedwetting
Status: COMPLETED
Conditions: Enuresis
Interventions: DRUG: ibuprofen; pseudoephedrine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Acceptance and Preference of Lidocaine Gel Compared to Injection Anesthesia After Non Surgical Periodontal Treatment
Status: COMPLETED
Conditions: Periodontitis
Interventions: DRUG: Lidocaine Hydrochloride 1% Gel|DRUG: Articaine hydrochloride/epinephrine (adrenaline) hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Low Dose β-carotene Supplementation Diminishes Oxidative Stress in Type 2 Diabetics and Healthy Individuals
Status: COMPLETED
Conditions: Diabetes Mellitus|Oxidative Stress|Iron Metabolism Disorders
Interventions: DIETARY_SUPPLEMENT: Betacarotene|DIETARY_SUPPLEMENT: Controls. No treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hematopoietic Stem Cell Support in Vasculitis
Status: TERMINATED
Conditions: Vasculitis
Interventions: BIOLOGICAL: Autologous Stem Cell Transplant|BIOLOGICAL: Allogeneic Stem Cell Transplant|DRUG: Cyclophosphamide|DRUG: ATG (rabbit)|DRUG: G-CSF|DRUG: Campath-1h|DRUG: Fludarabine|DRUG: Tacrolimus|DRUG: Mesna
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Feasibility Study of Enteral LVT vs. Standard of Care for Seizure Control in Pediatric CM
Status: COMPLETED
Conditions: Seizure|Epilepsy|Cerebral Malaria
Interventions: DRUG: Oral Levetiracetam|DRUG: Standard AED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of the V116 Vaccine for Children and Teenagers (V116-013)
Status: RECRUITING
Conditions: Pneumococcal Infection
Interventions: BIOLOGICAL: V116|BIOLOGICAL: PPSV23
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Modified Virus VSV-IFNbetaTYRP1 in Treating Patients With Stage III-IV Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Metastatic Choroid Melanoma|Metastatic Melanoma|Metastatic Mucosal Melanoma|Metastatic Uveal Melanoma|Pathologic Stage III Cutaneous Melanoma AJCC v8|Pathologic Stage IIIA Cutaneous Melanoma AJCC v8|Pathologic Stage IIIB Cutaneous Melanoma AJCC v8|Pathologic Stage IIIC Cutaneous Melanoma AJCC v8|Pathologic Stage IIID Cutaneous Melanoma AJCC v8|Pathologic Stage IV Cutaneous Melanoma AJCC v8|Unresectable Melanoma
Interventions: DRUG: Recombinant Vesicular Stomatitis Virus-expressing Interferon-beta and Tyrosinase Related Protein 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial In Pediatric Patients With Familial Adenomatous Polyposis (FAP)
Status: TERMINATED
Conditions: Adenomatous Polyposis Coli
Interventions: DRUG: Celecoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Liposomal Cytarabine, Daunorubicin, and Gemtuzumab Ozogamicin for the Treatment of Relapsed Refractory Pediatric Patients With Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia
Interventions: DRUG: Gemtuzumab Ozogamicin|DRUG: Liposome-encapsulated Daunorubicin-Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "EFFECTS OF KINESIO-TAPING ON PAIN, POSTURAL STABILITY AND FUNCTION IN PERSONS WITH DISCOGENIC LOW BACK PAIN"
Status: ENROLLING_BY_INVITATION
Conditions: Low Back Pain|Low Back Pain, Mechanical
Interventions: PROCEDURE: Kinesiotaping|PROCEDURE: Control Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ciprofloxacin Versus Levofloxacin on QTc-interval and Dysglycemia
Status: COMPLETED
Conditions: QTc Prolongation, Hyperglycemia, Hypoglycemia
Interventions: DRUG: Ciprofloxacin 400 MG/200 ML Intravenous Solution|DRUG: Levofloxacin 750 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Posterior Capsule Opacification After Lens Capsule Polishing
Status: UNKNOWN
Conditions: Posterior Capsule Opacification
Interventions: PROCEDURE: Capsular polishing|OTHER: Non capsular polishing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of a Fortified Balanced Energy-Protein Supplement on Birth Outcome and Child Growth in Houndé District, Burkina Faso.
Status: COMPLETED
Conditions: Small for Gestational Age at Delivery|Low Birth Weight|Prematurity|Infant Malnutrition
Interventions: DIETARY_SUPPLEMENT: Fortified balanced energy-protein (BEP) supplement|DIETARY_SUPPLEMENT: Fe and folic acid supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Analgesic Effects Of Dexamethasone; Its Use To Reduce Post Operative Pain Scores
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Autologous Adipose-Derived Stem Cell Transplantation in Type 2 Diabetics
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: PROCEDURE: Autologous Adipose-derived Stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ublituximab in Combination With Lenalidomide in Patients With B-Cell Lymphoid Malignancies
Status: TERMINATED
Conditions: Non-Hodgkins Lymphoma|Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma|B-cell Lymphomas|Marginal Zone Lymphoma|Mantle Cell Lymphoma|Waldenstrom's Macroglobulinemia
Interventions: DRUG: Ublituximab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of Bioavailability Of Two Sildenafil 100mg Oral Tablet Formulations
Status: COMPLETED
Conditions: Healthy Males
Interventions: DRUG: Treatment A|DRUG: Blood samples for the analysis of sildenafil in plasma|DRUG: Treatment B|OTHER: Blood samples for the analysis of sildenafil in plasma|DRUG: Treatment C|OTHER: Blood samples for the analysis of sildenafil in plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vitamin B6 Dependence of One-Carbon Metabolism
Status: COMPLETED
Conditions: Vitamin B6 Deficiency
Interventions: DIETARY_SUPPLEMENT: Arm 1 glycine and leucine|DIETARY_SUPPLEMENT: Arm 2 Intervention of Serine and methionine infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial for the Diagnosis of Sarcoidosis
Status: COMPLETED
Conditions: Sarcoidosis
Interventions: PROCEDURE: EUS-FNA/EBUS-TBNA + BAL|PROCEDURE: EBB + TBLB + BAL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Telitacicept for Injection (RC18) in Subjects With IgA Nephropathy
Status: TERMINATED
Conditions: IgA Nephropathy
Interventions: DRUG: Telitacicept 160mg|DRUG: Telitacicept 240mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New Protocol With Diluted Citrate in Continuous Techniques
Status: COMPLETED
Conditions: Acute Renal Failure|Dialysis; Complications|Citrate Poisoning
Interventions: OTHER: the same citrate dosification in both types
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of WTX-124 as Monotherapy and in Combination With Pembrolizumab (Pembro) in Patients With Selected Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Metastatic Solid Tumor|Advanced Solid Tumor
Interventions: DRUG: WTX-124|DRUG: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Plasma Concentration of YM178 OCAS Tablet (Mirabegron) in Healthy Chinese Volunteers
Status: COMPLETED
Conditions: Healthy Chinese Volunteers
Interventions: DRUG: YM178
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Incidence of Neutropenic Enterocolitis Study in Acute Myeloid Leukemia Patients During Intensive Therapy
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: OTHER: prospective study on digestive affections in an homogeneous cohort of hematological patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunotherapy in Combination With Chemoradiation in Patients With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Squamous Cell of Head and Neck|Carcinoma, Non-Small-Cell Lung|Small Cell Lung Carcinoma
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|DRUG: Cisplatin (dose level 4)|DRUG: Cisplatin (dose level 3)|DRUG: Carboplatin (dose level 1)|DRUG: Carboplatin (dose level 2)|DRUG: Etoposide (dose level 1)|DRUG: Etoposide (dose level 2)|DRUG: Paclitaxel|DRUG: Pemetrexed|RADIATION: External beam radiation (dose level 1)|RADIATION: External beam radiation (dose level 2)|RADIATION: External beam radiation (hyperfractionated)|DRUG: Cisplatin (dose level 1)|DRUG: Cisplatin (dose level 2)|RADIATION: External beam radiation (standard)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LEVANT Japan Clinical Trial
Status: COMPLETED
Conditions: Femoral Arterial Stenosis|Stenosis of Popliteal Arteries|Femoral Artery Occlusion|Occlusion of Popliteal Arteries
Interventions: DEVICE: MD02-LDCB Paclitaxel coated balloon catheter|PROCEDURE: Standard Uncoated Balloon Angioplasty Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Emergency Department Connection to Care With Buprenorphine for Opioid Use Disorder
Status: COMPLETED
Conditions: Opioid-use Disorder
Interventions: BEHAVIORAL: Employ a multifaceted approach to facilitate clinical protocol implementation|DRUG: Initiate BUP (SL-BUP or XR-BUP) in the ED
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy and Safety of At-home Transcutaneous Electrical Nerve Stimulation in Insomnia
Status: UNKNOWN
Conditions: Insomnia
Interventions: DEVICE: Transcutaneous Trigeminal Electrical Nerve Stimulation using YPS-401B|DEVICE: Sham Stimulation using YPS-401B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination SBRT With TACE for Unresectable Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Carcinoma, Hepatocellular|Hepatobiliary Neoplasm|Liver Carcinoma
Interventions: PROCEDURE: TACE|PROCEDURE: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Search for Transcriptional Biomarkers in a Conversion Protocol From Calcineurin Inhibitors to Mycophenolate Mofetil
Status: UNKNOWN
Conditions: Gene Expression|Immunosuppression Conversion|Liver Transplantation
Interventions: DRUG: conversion from CNI to MMF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase I of Human Papillomavirus (HPV) DNA Plasmid (VGX-3100) + Electroporation for CIN 2 or 3
Status: COMPLETED
Conditions: Papillomavirus Infections
Interventions: BIOLOGICAL: VGX-3100
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplant (SCT) for Dyskeratosis Congenita or SAA
Status: COMPLETED
Conditions: Dyskeratosis Congenita|Aplastic Anemia
Interventions: DRUG: Campath 1H|DRUG: Cyclophosphamide|DRUG: Fludarabine|PROCEDURE: Total Body Irradiation|PROCEDURE: Stem Cell Transplantation|DRUG: antithymocyte globulin|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare the Impact of Xuezhikang and Atorvastatin on Glucose Metabolism in Dyslipidemia Patients With Prediabetes
Status: COMPLETED
Conditions: Metabolism Disorder, Lipid|Metabolism Disorder, Glucose
Interventions: DRUG: Xuezhikang Capsule|DRUG: Atorvastatin Calcium Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individual Food Preferences for the Mediterranean Diet in Cancer Patients
Status: RECRUITING
Conditions: Neoplasms
Interventions: OTHER: Self-questionnaire|OTHER: Self-questionnaire|OTHER: Self-questionnaire|OTHER: Self-questionnaire|OTHER: Self-questionnaire|OTHER: Self-questionnaire|OTHER: Self-questionnaire|OTHER: Self-questionnaire|OTHER: Self-questionnaire|OTHER: Self-questionnaire|OTHER: Self-questionnaire|OTHER: Self-questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Controlled Trial of Panhematin in Treatment of Acute Attacks of Porphyria
Status: COMPLETED
Conditions: Acute Porphyrias
Interventions: BIOLOGICAL: Panhematin|OTHER: Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Knee Osteoarthritis With Allogenic Mesenchymal Stem Cells
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Arthritis of Knee|Knee Osteoarthritis
Interventions: OTHER: Allogenic mesenchymal stromal cells injection|DRUG: Hyaluronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Children With Acute Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: asparaginase|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: dexamethasone|DRUG: doxorubicin hydrochloride|DRUG: idarubicin|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: pegaspargase|DRUG: prednisone|DRUG: thioguanine|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lumbosacral Muscle Sensitivity & Pressure Pain Threshold After Kettlebell Swings
Status: COMPLETED
Conditions: Muscle Soreness|Muscle Weakness|Muscle Tenderness
Interventions: OTHER: Kettlebell Swing|OTHER: Isometric Hold|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Fenofibrate and Pravastatin in HIV-Positive Patients With Abnormal Blood Lipids
Status: COMPLETED
Conditions: HIV Infections|Lipodystrophy
Interventions: DRUG: Pravastatin sodium|DRUG: Fenofibrate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy of SAP Block Versus ESP Block in VATS Surgery
Status: COMPLETED
Conditions: Regional Anesthesia Morbidity
Interventions: PROCEDURE: regional anaesthesia with Levobupivicaine 0.25% 30mls with two methods either erector spinae plane block or serratus anterior plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of a Telephone-based Support Intervention on the Long-term Well-being of Women Undergoing Termination of Pregnancy for Fetal Anomaly
Status: WITHDRAWN
Conditions: Psychological Sequelae of Termination of Pregnancy for Fetal Anomaly
Interventions: BEHAVIORAL: supportive call
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Therapy of Metastatic Breast Cancer With Paclitaxel and Liposomal Doxorubicin
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: liposomal Doxorubicin|DRUG: Myocet / Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health Literacy and Smoking Cessation in Low-SES Diverse Smokers - Project HALT II
Status: WITHDRAWN
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Questionnaire|BEHAVIORAL: In-Depth Interviews|OTHER: Breath Test|DRUG: Nicotine Patches|BEHAVIORAL: Advice plus Phone Counseling|BEHAVIORAL: Advice plus Counseling Sessions|BEHAVIORAL: Self Assessment Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Helicobacter Pylori Infection Eradication in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Response to Levodopa|Motor Outcomes|Quality of Life Outcomes
Interventions: DRUG: Eradication therapy for H.pylori infection|DRUG: Eradication of Helcobacter Pylori|DRUG: Eradication therapy for Helicobacter pylori
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Dentin Hypersensitivity Reduction Over a 1-month Period
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: OTHER: Gluma|OTHER: fluoride varnish|OTHER: Tetric N-Bond self-etch adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Assess the Effects of Hepatic Ultrasound Insonification on Subjects With T2DM
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DEVICE: Hepatic Ultrasound Insonification
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Magnetic Stimulation to Treat VT Storm
Status: COMPLETED
Conditions: Ventricular Tachycardia
Interventions: DEVICE: Magstim SuperRapid|DEVICE: Magstim SuperRapid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT