pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Total Body Irradiation and Cladribine Before Allogeneic Hematopoietic Cell Transplantation in Patients With AML (Acute Myeloid Leukemia) and Myelodysplastic Syndromes
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia Myelodysplastic Syndromes
Interventions: DRUG: Cladribine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis
Status: TERMINATED
Conditions: Pruritus|Atopic Dermatitis
Interventions: DRUG: difelikefalin 0.25 mg|DRUG: difelikefalin 0.5 mg|DRUG: TCS Cream|DRUG: Placebo|DRUG: Vehicle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Patients With Advanced Solid Tumors, Breast Cancer or Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: Breast Cancer|Ovarian Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: BMS-247550
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Larazotide Acetate for the Relief of CeD Symptoms
Status: TERMINATED
Conditions: Celiac Disease
Interventions: DRUG: Larazotide|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determining the Glycemic Effects of Sunflower Pasta
Status: COMPLETED
Conditions: Potential Abnormality of Glucose Tolerance|Appetitive Behavior
Interventions: OTHER: Glucose as reference food|OTHER: Tagliatella control|OTHER: 5% sunflower tagliatella|OTHER: 16% sunflower tagliatella|OTHER: 16% sunflower penne|OTHER: 16% sunflower fusilli
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Randomized Placebo Controlled Efficacy And Safety Study Investigating GW876008 In Patients With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome (IBS)
Interventions: DRUG: GW876008|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Short Period of Proactive Community Case Management (ProCCM) to Improve Early Care-seeking for Fever in Sierra Leone
Status: NOT_YET_RECRUITING
Conditions: Health Services Research
Interventions: BEHAVIORAL: Proactive community case management|BEHAVIORAL: Strengthened SBCC and stock out mitigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PLD-cyclophosphamide-Nab-P Continuously Combined With Dual HER2 Blockage for HER2-positive Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|HER2-positive Breast Cancer
Interventions: DRUG: pegylated liposomal doxorubicin (PLD) plus cyclophosphamide followed by Nab-paclitaxel (Nab-P) ,continuously combined with dual HER2 blockage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guiding Opioid Administration in Patients With Regional Anesthesia
Status: COMPLETED
Conditions: Nociceptive Pain|Pain, Postoperative|Analgesia|Anesthesia Recovery Period|Opioid Use
Interventions: PROCEDURE: SPI (Surgical Pleth Index)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Platelet-rich Plasma (PRP) Therapy in Patients With Brittle Nail Syndrome
Status: COMPLETED
Conditions: Nail Diseases
Interventions: DEVICE: Platelet-rich plasma|DEVICE: Platelet-poor plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome
Status: COMPLETED
Conditions: PTEN Gene Mutation|PTEN Hamartoma Tumor Syndrome
Interventions: DRUG: RAD001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Isisekelo Sempilo Trial to Optimize Peer (Thetha Nami) Delivery of HIV Prevention to Young People in Rural KwaZulu-Natal
Status: COMPLETED
Conditions: HIV Prevention
Interventions: BEHAVIORAL: Standard of Care SOC|BEHAVIORAL: SRH enhanced Isisekelo Sempilo|BEHAVIORAL: Peer-support (Thetha-Nami)|BEHAVIORAL: SOC + SRH + peer-support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Epidemiology of SARS-CoV-2 and Mortality to Covid19 Disease in French Cancer Patients
Status: UNKNOWN
Conditions: Cancer & COVID 19
Interventions: DRUG: Hydroxychloroquine|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pivotal Study of the FRED Stent System in the Treatment of Intracranial Aneurysms
Status: COMPLETED
Conditions: Intracranial Aneurysms
Interventions: DEVICE: Flow Re-Direction Endoluminal Device (FRED)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UniSA BackOff! Study: Adelaide PrenaBelt Trial
Status: TERMINATED
Conditions: Stillbirth|Infant, Low Birth Weight|Infant, Very Low Birth Weight|Sleep-Disordered Breathing|Infant, Small for Gestational Age|Fetal Hypoxia|Pregnancy Complications|Fetal Growth Retardation
Interventions: DEVICE: PB2-1 prototype|DEVICE: PB2-2 prototype|DEVICE: PB2-3 prototype|DEVICE: PB2-4 prototype|DEVICE: PB2-5 prototype|DEVICE: Ajuvia-Active|DEVICE: Ajuvia-Passive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Levels of Interleukin-6 andTransforming Growth Factor Beta in HCV Patients Sera
Status: UNKNOWN
Conditions: Hepatitis C, Chronic
Interventions: DRUG: sofosbuvir and daclatasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biological Therapy After Chemotherapy in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: therapeutic autologous lymphocytes|DRUG: cyclophosphamide|DRUG: prednisone|DRUG: vincristine sulfate|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Epidural Analgesia in Spine Fusion Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: 0.125% Bupivacaine HCL @ 4-5 ml/h|DRUG: 0.125% Bupivacaine HCL , Morphine sulphate @ 3 mg 3-5 ml/h|DRUG: 0.125% Bupivacaine, Fentanyl 100 mic @ 3-5 ml/h
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Fish Oil Supplementation in 3rd Trimester of Pregnancy on Maternal and Offspring Health
Status: COMPLETED
Conditions: Preterm Delivery|Atopy|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Fish oil|DIETARY_SUPPLEMENT: Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study on the Effects of Different Premedication for LISA on Stress and Cerebral Tissue Oxygenation in Preterm Infants
Status: WITHDRAWN
Conditions: Respiratory Distress Syndrome|Surfactant Deficiency Syndrome Neonatal|Near Infrared Spectroscopy
Interventions: DRUG: Fentanyl|DRUG: Sucrose 24% Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of an Individualized Training Program on Severity Markers of Obstructives Sleep Apnea/Hypopnea Syndrome (OSAS)
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Exercise Training Therapy
Interventions: OTHER: training and educational program|OTHER: educational program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Modafinil on Brain Function in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Modafinil|PROCEDURE: Functional MRI|PROCEDURE: Neuropsychological Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: OTHER
Clinical trial: Effectiveness of Low Energy Laser Treatment in Oral Mucositis Induced by Chemotherapy and Radiotherapy in Head and Neck Cancer
Status: UNKNOWN
Conditions: Oral Mucositis
Interventions: DEVICE: Low intensity laser for oral mucositis|DEVICE: Low intensity laser for oral mucositis switch off
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Single Administration of 3 Doses of Dysport® for the Treatment of Benign Essential Blepharospasm
Status: COMPLETED
Conditions: Blepharospasm
Interventions: BIOLOGICAL: Botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Diaphragmatic Neuromodulation
Status: RECRUITING
Conditions: Neurosurgery|Phrenic Nerve Stimulation|Postoperative Delirium
Interventions: OTHER: Phrenic nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Data Validation of Novel Wireless Cortrium C3 Monitor for Continuous Electrocardiogram Measurements
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Cortrium C3 device|DEVICE: Holter device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Ketone Supplementation in Adolescents Post-Concussion
Status: COMPLETED
Conditions: Concussion, Mild|Concussion, Severe|Concussion, Brain|Concussive Injury|Sport Injury|Sports Injuries in Children
Interventions: DIETARY_SUPPLEMENT: Ketone|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: SUBLIVAC® Birch PROBE Study
Status: COMPLETED
Conditions: Seasonal Rhinitis and/or Rhinoconjunctivitis|Birch Pollen Allergy
Interventions: DRUG: sublingual immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Rosuvastatin on Coronary Flow Reserve in Hypertensive Patients With Cardiovascular Risk
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Rosuvastatin|BEHAVIORAL: Life style modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nedaplatin/Docetaxel Versus Cisplatin/Docetaxel in Treatment of Advanced/Relapsed Squamous Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Docetaxel|DRUG: Nedaplatin|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Exposure to Rizatriptan 5-mg and 10-mg Oral Tablet (Combined Extension Protocols MK-0462-022, MK-0462-025, MK-0462-029)
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: Rizatriptan 5 mg|DRUG: Rizatriptan 10 mg|DRUG: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: T Cell Receptor Gene Therapy Targeting KK-LC-1 for Gastric, Breast, Cervical, Lung and Other KK-LC-1 Positive Epithelial Cancers
Status: RECRUITING
Conditions: Kita-kyushu Lung Cancer Antigen 1, Human
Interventions: DRUG: IL-2 (Aldesleukin)|DRUG: Cyclophosphamide|BIOLOGICAL: KK-LC-1 TCR|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants With Advanced or Metastatic ROS1 Non-small Cell Lung Cancer (NSCLC) With and Without Central Nervous System (CNS) Metastases
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Entrectinib|DRUG: Crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexcom G6 Observational Study
Status: COMPLETED
Conditions: Diabetes
Interventions: DEVICE: Dexcom G6 CGM - Continues Glucose Monitoring sensor system|DIAGNOSTIC_TEST: POC BG - Point-of-Care Blood Glucose monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: DecipHER Trial - DC1 Tx for Early-Stage TNBC and ER Low Positive Breast Cancer
Status: RECRUITING
Conditions: Triple Negative Breast Cancer|HER2-negative Breast Cancer
Interventions: BIOLOGICAL: HER2 - primed Dendritic cells|BIOLOGICAL: HER3 - primed Dendritic cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pectoral Nerve Block Type-II and Rhomboid Intercostal Block for Pain Management Following Mastectomy Surgery
Status: COMPLETED
Conditions: Breast Cancer|Breast Neoplasms|Breast Diseases|Breast Fibroadenoma
Interventions: OTHER: PECS block|OTHER: Rhomboid intercostal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells for The Treatment of Chronic Obstructive Pulmonary Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease Moderate
Interventions: BIOLOGICAL: UMC119-06
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cellular Immuno-Therapy for COVID-19 ARDS Randomized Clinical Trial
Status: UNKNOWN
Conditions: Covid19|Acute Respiratory Distress Syndrome
Interventions: BIOLOGICAL: UC-MSCs|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label, Single-arm Clinical Study Evaluating the Safety and Efficacy of ICI201 Infusion in Relapsed/Refractory Multiple Myeloma
Status: WITHDRAWN
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: DRUG: ICI201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minoxidil 2% for Eyebrow Enhancement
Status: COMPLETED
Conditions: Hypotrichosis of Eyebrows|Thinning Eyebrows
Interventions: DRUG: Minoxidil lotion 2%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Lower Limb Concentric Versus Eccentric Dynamic Resistance Training on Agility and Speed in Badminton Players
Status: COMPLETED
Conditions: Sports Physical Therapy
Interventions: OTHER: Concentric Lower Limb Training Program|OTHER: Eccentric Lower Limb Training Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Less Infections for the Diabetic Foot
Status: COMPLETED
Conditions: Diabetic Foot
Interventions: PROCEDURE: Surgical debridement (if needed)|DIAGNOSTIC_TEST: Microbiological sampling|PROCEDURE: Revascularisation (if needed).|DEVICE: Off-loading|BEHAVIORAL: Patient's education and instructions|PROCEDURE: Wound debridement|DRUG: Antibiotic duration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of S-ketamine in Elective Cesarean Section
Status: UNKNOWN
Conditions: Anesthesia|Analgesia|Depression|Cesarean Section|Parturition
Interventions: DRUG: S-ketamine|OTHER: normal saline|DRUG: S-ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Electro-acupuncture for Irritable Bowel Syndrome With Constipation
Status: NOT_YET_RECRUITING
Conditions: Irritable Bowel Syndrome With Constipation
Interventions: DEVICE: Acupuncture needles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Use of JSP191 in Matched Unrelated Donor Transplantation for Chronic Granulomatous Disease (CGD)
Status: RECRUITING
Conditions: Chronic Granulomatous Disease|CGD
Interventions: BIOLOGICAL: JSP191
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-Session Intervention Targeting Emotional Awareness, Clarity, and Acceptance to Reduce Depression/Anxiety
Status: COMPLETED
Conditions: Depression|Anxiety
Interventions: BEHAVIORAL: Visitor Mindset|BEHAVIORAL: Relaxing with Nature
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Common and Differentiated Representations Between Social Exclusion and Social Separation
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: Intranasal Oxytocin|DRUG: Intranasal Arginine Vasopressin|DRUG: Intranasal placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nintedanib in Lung Transplant Recipients With Bronchiolitis Obliterans Syndrome Grade 0p-1-2
Status: RECRUITING
Conditions: Lung-transplant Recipients
Interventions: DRUG: Nintedanib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-64304500 as Add-on Therapy in Participants With Active Crohn's Disease
Status: WITHDRAWN
Conditions: Crohn Disease
Interventions: DRUG: JNJ-64304500|DRUG: Placebo|DRUG: Adalimumab|DRUG: Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Post-Operative Anesthesia With Either Lidocaine or Bupivacaine
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: DRUG: Xylocaine 2 % with 1:100,000 epinephrine|DRUG: Bupivicaine 0.5% with 1:200,000 epinephrine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Three Drug Combination Therapies in HIV-Infected Patients Who Have Never Been Treated With Anti-HIV Drugs
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Nevirapine|DRUG: Lamivudine|DRUG: Stavudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Pre-operative Carriage of Respiratory VIRUSes, and Acute Respiratory Distress Syndrome After Heart Surgery
Status: COMPLETED
Conditions: Heart; Surgery, Heart, Functional Disturbance as Result
Interventions: DIAGNOSTIC_TEST: Screening for respiratory virus infection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Olaparib and Onalespib in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Recurrent Ovarian, Fallopian Tube, Primary Peritoneal, or Triple-Negative Breast Cancer
Status: COMPLETED
Conditions: Metastatic High Grade Fallopian Tube Serous Adenocarcinoma|Metastatic Malignant Solid Neoplasm|Metastatic Primary Peritoneal Serous Adenocarcinoma|Metastatic Triple-Negative Breast Carcinoma|Platinum-Resistant Fallopian Tube Carcinoma|Platinum-Resistant Ovarian Carcinoma|Platinum-Resistant Primary Peritoneal Carcinoma|Recurrent Breast Carcinoma|Recurrent High Grade Fallopian Tube Serous Adenocarcinoma|Recurrent High Grade Ovarian Serous Adenocarcinoma|Recurrent Primary Peritoneal High Grade Serous Adenocarcinoma|Recurrent Triple-Negative Breast Carcinoma|Refractory Fallopian Tube Serous Adenocarcinoma|Refractory Ovarian Serous Adenocarcinoma|Refractory Primary Peritoneal Serous Adenocarcinoma|Refractory Triple-Negative Breast Carcinoma|Unresectable High Grade Fallopian Tube Serous Adenocarcinoma|Unresectable Malignant Solid Neoplasm|Unresectable Primary Peritoneal Serous Adenocarcinoma
Interventions: DRUG: Olaparib|DRUG: Onalespib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polymorphonuclear Cells' Sensitivity to Aggregatibacter Actinomycetemcomitans Bacteria in Patients With Aggressive Periodontitis
Status: UNKNOWN
Conditions: Periodontal Disease
Interventions: OTHER: blood extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Evaluation of a Cochlear Implant Sound Processor
Status: COMPLETED
Conditions: Hearing Loss|Ear Diseases|Hearing Disorders|Otorhinolaryngologic Diseases
Interventions: DEVICE: Naída Cochlear Implant Q90 sound processor (Naida CI Q90) & software|DEVICE: 301-M062 sound processor & software
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CGM Utilization With IV Insulin EndoTool and Subcutaneous Insulin in the Neuro ICU
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Type 2 Diabetes Mellitus|Hyperglycemia
Interventions: DEVICE: Libre 2.0 CGM in patients taking subcutaneous insulin with concomitant high dose glucocorticoids
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transgender Estradiol Affirming Therapy
Status: RECRUITING
Conditions: Transgenderism
Interventions: DRUG: Transdermal patch|DIAGNOSTIC_TEST: Pro-thrombotic markers|DIAGNOSTIC_TEST: Metabolic markers|DIAGNOSTIC_TEST: Hormone Profile|DRUG: Sublingual Tablet|DRUG: Sublingual Tablet|DRUG: Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Radiation Therapy Plus Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Relapsed or Refractory T-cell Lymphoma, Hodgkin's Lymphoma, or Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: busulfan|DRUG: cyclophosphamide|DRUG: etoposide|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Endothelial Progenitor Cells Transplantation for Chronic Ischemic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Intravenous stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Xience/Promus Versus Cypher in rEducing Late Loss After stENTing
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Everolimus-eluting stent (Xience or Promus)|DEVICE: Sirolimus-eluting stent (Cypher)|DRUG: 6-month clopidogrel therapy|DRUG: 12-month clopidogrel therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antenatal Corticosteroid in Elective Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Intra-tumor Injection of Drug-eluting Microspheres With Multiple Drugs
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Solid Tumor, Adult
Interventions: DRUG: Injection of drug-eluting microspheres with multiple drugs into solid tumors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Norwegian Psychomotor Physiotherapy - The Effect on Quality of Life
Status: COMPLETED
Conditions: Pain|Stress|Psychosomatic Diseases|Muscle Skeletal Disorders
Interventions: BEHAVIORAL: Individual NPMP to the participants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Liposomal Doxorubicin and PSC 833 in Treating Patients With AIDS-Related Kaposi's Sarcoma or Other Advanced Cancers
Status: COMPLETED
Conditions: Sarcoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: pegylated liposomal doxorubicin hydrochloride|DRUG: PSC 833
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: Endoscopic Therapy of Malignant Bile Duct Strictures
Status: TERMINATED
Conditions: Obstruction of Biliary Tree|Biliary Tract Cancer|Biliary Tract Neoplasms
Interventions: DEVICE: Radiofrequency ablation catheter (Habib EndoHBP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Cicletanine for Pulmonary Arterial Hypertension (PAH)
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Cicletanine|DRUG: Cicletanine Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Increasing Dose Study to Assess Safety and Tolerability of DX-2930 in Healthy Subjects
Status: COMPLETED
Conditions: Hereditary Angioedema (HAE)
Interventions: DRUG: DX-2930|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROM Collected Via a WebApp Versus a Touch Screen Solution Among Patients With SLE
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DEVICE: PROM registration via the DANBIO WebApp and the outpatient touchscreen in a randomised order
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Caffeine Versus Probiotic on Preterm Neonates With Bronchopulmonary Dysplasia
Status: RECRUITING
Conditions: Bronchopulmonary Dysplasia
Interventions: DRUG: Caffeine|DRUG: Probiotic Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of High-Dose Rituximab With Temozolomide as Treatment for Primary Central Nervous System (CNS) Lymphoma
Status: TERMINATED
Conditions: Primary Central Nervous System Lymphoma
Interventions: DRUG: Rituximab plus Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome Study in Refractory Epilepsy (SOPHIE)
Status: COMPLETED
Conditions: Epilepsy
Interventions: OTHER: AEP score available to the treating physician
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Contrast Agents in Liver MR for the Detection of Hepatic Metastases
Status: RECRUITING
Conditions: Oligometastatic Disease|Liver Metastases|Colorectal Cancer
Interventions: DRUG: Gadoxetate disodium|DRUG: Gadobenate dimeglumine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Allogeneic Adipose Tissue Mesenchymal Stem Cells in Diabetic Patients With Critical Limb Ischemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Limb Ischemia|Diabetic Foot
Interventions: DRUG: High dose allogeneic mesenchymal stromal cells|DRUG: Low dose allogeneic mesenchymal stromal cells|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid Versus Misoprostol in Reducing Blood Loss in Cesarean Section in Primigravida
Status: COMPLETED
Conditions: Cesarean Section Complications|Blood Loss, Surgical|Misoprostol|Tranexamic Acid
Interventions: DRUG: Tranexamic acid|DRUG: Misoprostol 200mcg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Anlotinib in Patients With Gastric Cancer(ALTER0503)
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Anlotinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects Of Remote Organ Ischemic Preconditioning On Systemic Inflammatory And Glycocalyx Integrity Parameters
Status: COMPLETED
Conditions: Remote Organ Ischemic Preconditioning
Interventions: PROCEDURE: Remote ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety & Immunogenicity of MMR Vaccine by DSJI to That by Needle-Syringe in 15-18 Months Old Children
Status: COMPLETED
Conditions: Immune Response to MMR Vaccine
Interventions: BIOLOGICAL: MMR vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vaginal Misoprostol and Foley Catheter for Induction of Labor
Status: COMPLETED
Conditions: Induction of Labor Affected Fetus / Newborn
Interventions: DRUG: Misoprostol|DEVICE: Foley Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of 6MP Metabolite Levels on Infliximab Pharmacokinetics and Anti-infliximab Antibodies in Crohn's Disease
Status: UNKNOWN
Conditions: Inflammatory Bowel Disease|Crohn's Disease
Interventions: DRUG: Infliximab|DRUG: thiopurine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Training Based on the Pilates Method on the Blood Pressure of Hypertensive Women
Status: COMPLETED
Conditions: Hypertension
Interventions: OTHER: Traditional Pilates group|OTHER: Modified Pilates group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study for Efficacy and Safety Outcomes Data in Japanese Patients With Severe Hemophilia A
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemophilia A
Interventions: BIOLOGICAL: Valoctocogene roxaparvovec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody-Based Sequential Therapy for Deep Remission in Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: KRdD followed by auto-HCT|DRUG: KRdD only
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OTL38 for Intra-operative Imaging of Folate Receptor Positive Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: OTL38|DEVICE: near infrared camera imaging system|PROCEDURE: laparotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Humidification Needs
Status: TERMINATED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Condition A: CPAP with No Humidification|DEVICE: Condition B: CPAP with No Humidification|DEVICE: Condition C: CPAP with Cold Passover|DEVICE: Condition D: CPAP with Modified humidifier|DEVICE: Condition E: CPAP with Ambient Tracking|DEVICE: Condition F: CPAP with Heated Humidification|DEVICE: Condition G: CPAP with Heated Humidification|DEVICE: Condition H: CPAP with New level humidification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Topical Bromfenac Ophthalmic Solution vs. Placebo in Subjects With Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Bromfenac|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: DNA Analysis of Tumor Tissue Samples From Young Patients With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Childhood Acute Lymphoblastic Leukemia in Remission|Recurrent Childhood Acute Lymphoblastic Leukemia
Interventions: OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Escitalopram vs. Reboxetine on Gastro-intestinal Sensitivity of Patients With Major Depressive Disorder
Status: UNKNOWN
Conditions: Major Depression|Pain|Abdominal Pain
Interventions: DRUG: escitalopram|DRUG: Reboxetine|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imiquimod 5% Cream for the Treatment of Periocular Basal Cell Carcinoma
Status: UNKNOWN
Conditions: Carcinoma, Basal Cell
Interventions: DRUG: Imiquimod 5% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 32-week Trial to Evaluate the Efficacy and Safety of Tralokinumab in Subjects With Moderate-to-severe Atopic Hand Eczema Who Are Candidates for Systemic Therapy
Status: RECRUITING
Conditions: Atopic Dermatitis|Atopic Hand Eczema
Interventions: DRUG: Tralokinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of PF-00734200 in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: PF-00734200 30 mg QD|DRUG: PF-00734200 20 mg QD|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Diathermy Application on Immediate Sports Performance of Paralympic Swimmers
Status: UNKNOWN
Conditions: Athletic Performance
Interventions: DEVICE: Resistive Diathermy (INDIBA® Activ Ct9)|DEVICE: Resistive Diathermy OFF (INDIBA® Activ Ct9)|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Effect of a Strong CYP3A Inhibitor, on Surufatinib in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Surufatinib|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Plantarflexor PAS - Stroke
Status: COMPLETED
Conditions: Stroke|Hemiparesis|Gait Dysfunction
Interventions: OTHER: PAS at Rest|OTHER: PAS - Active|OTHER: PAS - Walking
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Antenatal Allopurinol During Fetal Hypoxia
Status: UNKNOWN
Conditions: Fetal Hypoxia|Reperfusion Injury
Interventions: DRUG: Allopurinol sodium|DRUG: Mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Ferric Derisomaltose on Postoperative Anemia in Spinal Deformity Surgery
Status: RECRUITING
Conditions: Perioperative Anemia|Surgery|Spinal Deformity|Adult
Interventions: DRUG: Ferric derisomaltose|DRUG: Ferrous succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Acupuncture and Laser Acupuncture in Treating Chemotherapy or Target Therapy-induced Hand-foot Syndrome
Status: NOT_YET_RECRUITING
Conditions: Hand-Foot Syndrome
Interventions: DEVICE: acupuncture|DEVICE: laser acupuncture|DEVICE: Sham-laser acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aerosol Delivery in Different Types of Nebulizers
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: Constant jet nebulizer|DEVICE: Breath enhanced nebulizer|DEVICE: Manual-actuated nebulizer|DEVICE: Breath-actuated nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Neurocognitive and Radiological Assessments in Adult Moyamoya Undergoing Surgery
Status: UNKNOWN
Conditions: Moyamoya Disease
Interventions: PROCEDURE: Surgical Revascularization|OTHER: Conservative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Pre-operative Systemic Therapy for Human Epidermal Growth Factor Receptor 2 (HER2) Amplified Breast Cancer
Status: TERMINATED
Conditions: Early-stage Breast Cancer|HER2-positive Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: Carboplatin|DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: Atezolizumab|DRUG: Trastuzumab emtansine|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Tolerability of Sodium Bicarbonate Toothpaste
Status: COMPLETED
Conditions: Oral Hygiene
Interventions: DRUG: Sodium bicarbonate plus sodium fluoride|DRUG: Sodium fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Imaging of DNA Damage Response by [18F]-Olaparib PET
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma (HNSCC)
Interventions: DIAGNOSTIC_TEST: [18F]-olaparib PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Defining a Dosing Regimen With Maximal Absorption for Oral Iron Supplementation During Pregnancy
Status: COMPLETED
Conditions: Iron Deficiency Anemia of Pregnancy
Interventions: DIETARY_SUPPLEMENT: Labeled iron solution (60mg and 120mg Ferrous Fumarate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Preterm Infants May Better Tolerate Warmer Feeds
Status: COMPLETED
Conditions: Prematurity|Feeding Disorder Neonatal
Interventions: OTHER: Room temperature|OTHER: Warmer temperature
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Short-chain Fatty Acids on Aerobic Endurance
Status: RECRUITING
Conditions: Aerobic Endurance|Metabolism
Interventions: DIETARY_SUPPLEMENT: High-amylose maize starch+acetate/butyrate|OTHER: Low-amylose maize starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Intravaginal Electrical Stimulation in Idiopathic Overactive Bladder
Status: COMPLETED
Conditions: Idiopathic Overactive Bladder|Electrical Stimulation|Bladder Training
Interventions: OTHER: Electrical stimulation (IVES)|OTHER: Bladder Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extubation Failure Prevention in High Risk Patients by High-flow Conditioned Oxygen Therapy vs. Standard Oxygen Therapy
Status: TERMINATED
Conditions: Respiratory Failure
Interventions: DEVICE: Optiflow (Fisher&Paykel)|DEVICE: Nasal cannulae or controlled oxygen concentration mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study of Lenalidomide in Combination With Bendamustine in Relapsed and Primary Refractory Hodgkin Lymphoma
Status: UNKNOWN
Conditions: Recurrent Adult Hodgkin Lymphoma
Interventions: DRUG: Lenalidomide|DRUG: Bendamustine|OTHER: Bio-specimen Retention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Resistance Training Period on Blood Pressure of Hypertensive Elderlies: Influence of the Polymorphism of the Angiotensin Converting Enzyme
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Use of Levosimendan Versus Milrinone in Open Heart Surgery in Infants
Status: UNKNOWN
Conditions: Low Cardiac Output Syndrome
Interventions: DRUG: Levosimendan|DRUG: Milrinone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Analysis of Long-Term Clinical Outcomes and 3D Spine Growth in Anterior Vertebral Body Tethering
Status: RECRUITING
Conditions: Scoliosis Idiopathic
Interventions: DEVICE: Anterior Vertebral Body Tethering
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial for Treatment of High Risk BC With Two Sequences of Neoadjuvant Chemotherapy With Pembrolizumab
Status: NOT_YET_RECRUITING
Conditions: Early Breast Cancer|Triple Negative Breast Cancer
Interventions: DRUG: Pembrolizumab injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carvedilol in Preventing Heart Failure in Childhood Cancer Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: DRUG: Carvedilol|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacogenomic Study|OTHER: Pharmacological Study|OTHER: Placebo Administration|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Palatinose™ on Weight Management and Body Composition
Status: COMPLETED
Conditions: Overweight and Obesity|Diet Modification|Body Weight
Interventions: OTHER: isomaltulose (Palatinose(TM)|OTHER: Sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IV Ketorolac on Platelet Function Post-Cesarean Delivery
Status: ACTIVE_NOT_RECRUITING
Conditions: Analgesia, Obstetrical|Coagulation Defect; Postpartum|Nonsteroidals (NSAIDs)Toxicity|Postpartum Hemorrhage|Postoperative Pain|Ketorolac Adverse Reaction|Blood Loss, Postoperative
Interventions: DRUG: Ketorolac Tromethamine 30 MG/ML|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Pharmacological Treatment of Vestibular Migraine in Children and Adolescent
Status: NOT_YET_RECRUITING
Conditions: Vestibular Migraine
Interventions: BEHAVIORAL: Lifestyle modifications|OTHER: Vestibular rehabilitation exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT