pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Lymph Node Mapping in Patients With Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: PROCEDURE: sentinel lymph node detection|DRUG: indocyanine green solution|DRUG: isosulfan blue|PROCEDURE: sentinel lymph node biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MLN0128 Compared to Sorafenib in Advanced or Metastatic Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma|Liver Cancer|HCC
Interventions: DRUG: MLN0128|DRUG: MLN0128 (RP2D)|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Creatine+HMB and Creatine+GAA Supplementation in Presarcopenic and Sarcopenic Individuals
Status: NOT_YET_RECRUITING
Conditions: Aging|Sarcopenia|Nutrition, Healthy
Interventions: DIETARY_SUPPLEMENT: CRE + HMB|DIETARY_SUPPLEMENT: CRE + GAA|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Segmental Trunk Stability Training on Sitting and Upper Limbs Functions in Children With Spastic Cerebral Palsy
Status: UNKNOWN
Conditions: Cerebral Palsy
Interventions: OTHER: Traditional Physical Therapy program|OTHER: Segmental trunk training A|OTHER: Segmental trunk training B|OTHER: Segmental trunk training C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effects of Oral NMRA-335140 in Participants With Major Depressive Disorder
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: NMRA-335140|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Effectiveness of an Off-the-shelf Single REnal Scalloped sTent-graft for HOstile NEck Infrarenal Abdominal Aortic Aneurysm
Status: RECRUITING
Conditions: Abdominal Aortic Aneurysm
Interventions: DEVICE: Endovascular Aortic Repair (EVAR)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Postoperative Management on Outcomes and Healing of Rotator Cuff Repairs
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: OTHER: Immediate Postoperative Therapy|OTHER: Delayed Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: To Evaluate Clinical Outcome and Injection Compliance of Scilin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin (Scilin N, BAY81-9924)|DRUG: Insulin (Scilin R _BAY81-9924|DRUG: Insulin(Scilin M30_BAY81-9924)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Rifampin and Efavirenz on the Pharmacokinetics of Fedratinib in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Fedratinib|DRUG: Rifampin|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of HypnoBirthing Training and Oxytocin Massage in Primiparous Pregnants
Status: COMPLETED
Conditions: Pregnancy Related
Interventions: OTHER: HypnoBirthing training and oxytocin massage group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of First-line L-glutamine With Gemcitabine and Nab-paclitaxel in Advanced Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Pancreatic Adenocarcinoma|Pancreatic Cancer|Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Gemcitabine|DRUG: Nab-paclitaxel|DRUG: L-glutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Random Selection of Patients From the SENTRY Study Who Have a Bioconverted Sentry IVC Filter in Situ With a Minimum Dwell Time of 24 Months From a Single Center Follow up
Status: COMPLETED
Conditions: Recurrent Pulmonary Embolism (Disorder)
Interventions: DIAGNOSTIC_TEST: IVUS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 506U78 in Treating Patients With Hematologic Cancer and Kidney or Liver Impairment
Status: TERMINATED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: DRUG: Compound 506U78
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motile Sperm Organelle Morphology Examination (MSOME) Influence on Intracytoplasmic Sperm Injection (ICSI) Outcomes in Infertile Couples
Status: COMPLETED
Conditions: Pregnancy
Interventions: OTHER: MSOME
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Human Papillomavirus Vaccine (Cervarix™) When Co-administered With GSK Biologicals' Hepatitis A Vaccine (Havrix®) in Healthy Female Adolescents Aged 9-14 Years
Status: WITHDRAWN
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: Cervarix™|BIOLOGICAL: Havrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Maintenance Aromatase Inhibitors (AIs)+ Everolimus vs AIs in Hormone Receptor Positive Metastatic Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer Metastatic
Interventions: DRUG: Everolimus|DRUG: Aromatase Inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pupillary Response After Glaucoma Medication
Status: COMPLETED
Conditions: Drug Effect (Glaucoma Drugs)
Interventions: DRUG: Latanoprost|DRUG: Timolol|DRUG: Dorzolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 2b Study to Evaluate RIST4721 in Palmoplantar Pustulosis (PPP)
Status: TERMINATED
Conditions: Palmoplantar Pustulosis
Interventions: DRUG: RIST4721|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Glypican 3 as Apredictive Marker in Colorectal Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: DIAGNOSTIC_TEST: glypican 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Exploratory Clinical Study of HRS-4642 Combined With Adebelimab in the Treatment of Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: HRS-4642|DRUG: Adebrelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Nelfinavir With Concurrent Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Nelfinavir (Viracept®) 1250 mg|OTHER: Chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of BPAP ST/T and BPAP ST / T Mode With AVAPS for Hypercapnic Respiratory Failure in ED
Status: COMPLETED
Conditions: Hypercapnic Respiratory Failure
Interventions: DEVICE: Noninvasive mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mifepristone and Two Doses of Misoprostol for Abortion at 11&12 Weeks
Status: TERMINATED
Conditions: Medical Abortion
Interventions: DRUG: Mifepristone + 2 doses of misoprostol 800 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Cord Stimulation Combined With Exercise in Persistent Spinal Pain Syndrome
Status: RECRUITING
Conditions: Failed Back Surgery Syndrome
Interventions: PROCEDURE: Exercise|PROCEDURE: Spinal Cord Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FastFrame Knee Spanning and Damage Control Kit PMCF
Status: TERMINATED
Conditions: Fracture|Fractures, Bone|Fractures, Closed|Fractures, Open
Interventions: DEVICE: FastFrame External Fixation System - Knee Spanning or Damage Control Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methotrexate Infusion Into Fourth Ventricle in Children With Recurrent Malignant Fourth Ventricular Brain Tumors
Status: COMPLETED
Conditions: Brain Tumor, Recurrent|Malignant Neoplasm of Fourth Ventricle of Brain
Interventions: PROCEDURE: Ommaya Reservoir|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label Randomized Multicenter Phase III Clinical Study Comparing Safety and Efficacy of Algeron (Cepeginterferon Alfa-2b) and and PegIntron (Peginterferon Alfa-2b) in Combination With Ribavirin as Combined Treatment of Chronic Hepatitis C in Human Immunodeficiency Virus-1 Infected Patients
Status: COMPLETED
Conditions: Hepatitis|Hepatitis C|Hepatitis C/ Human Immunodeficiency Virus Coinfection
Interventions: DRUG: Algeron|DRUG: PegIntron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EPITHINK: Epigenetic Drug Treatment and Therapeutic Immunotherapy With NKR-2
Status: WITHDRAWN
Conditions: AML, Adult|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: NKR-2 CAR-T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an 8 Component Botanical Supplement on Mild and Moderate Alzheimer's Patients
Status: COMPLETED
Conditions: Alzheimer Disease|Alzheimer Dementia
Interventions: DIETARY_SUPPLEMENT: ReBuilder|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MPA Versus Dydrogesterone for Management of Endometrial Hyperplasia Without Atypia
Status: COMPLETED
Conditions: Endometrial Hyperplasia Without Atypia
Interventions: DRUG: Medroxyprogesterone Acetate|DRUG: Dydrogesterone 10 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lifestyle and Pregnancy: The Clinical Effect of Lifestyle Intervention During Pregnancy in Obese Women
Status: COMPLETED
Conditions: Maternal Obesity|Gestational Weight Gain|Obstetric Complications
Interventions: OTHER: Lifestyle intervention|OTHER: Control|BEHAVIORAL: Physical activity, dietetic counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability and Pharmacokinetics of CSL360 in the Treatment of Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: CSL360
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Renal Effects of APX-115 in Subjects With Type 2 Diabetes and Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathies|Diabetes Mellitus, Type 2|Nephropathy, Diabetic
Interventions: DRUG: APX-115|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Pyrotinib Plus Vinorelbine in Comparison With Treatment of Physician's Choice in Participants With HER2-positive Locally Advanced or Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Pyrotinib|DRUG: Treatment of physician's choice|DRUG: vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Trastuzumab and Pyrotinib in HER2 Positive Locally Advanced or Metastatic Urothelial Carcinoma
Status: RECRUITING
Conditions: Carcinoma, Transitional Cell|HER-2 Gene Amplification
Interventions: DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Using Parenchymal Blood Volume(PBV) for Endovascular Treatment of Renal Arterial Stenosis
Status: UNKNOWN
Conditions: Renal Artery Stenosis|Renal Blood Perfusion
Interventions: PROCEDURE: EVT for RAS & PBV acquisition protocol for target kidneys
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Endostar Combined With Chemotherapy and Radiotherapy on Blood Vessels and Microenvironment of Tumor for Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Endostar|DRUG: Vinorelbine|DRUG: Cisplatin|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Prospective Comparison of the New EUS Guided Acquire TM Needle Biopsy vs EUS Guided Fine Needle Aspiration for Suspected Solid Gastrointestinal Lesions
Status: COMPLETED
Conditions: Solid Tumor|Histological Type of Neoplasm
Interventions: DEVICE: Conventional EUS FNA needle|DEVICE: Acquire FNB device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of the Efficacy and Safety of AMT-101 in Combination With Adalimumab in Subjects With Ulcerative Colitis (MARKET)
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: AMT-101 (oral)|OTHER: Placebo (oral)|COMBINATION_PRODUCT: Humira (adalimumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lung-MAP: Palbociclib as Second-Line Therapy in Treating Cell Cycle Gene Alteration Positive Patients With Recurrent Stage IV Squamous Cell Lung Cancer
Status: COMPLETED
Conditions: CCND1 Gene Amplification|CCND2 Gene Amplification|CCND3 Gene Amplification|CDK4 Gene Amplification|Recurrent Squamous Cell Lung Carcinoma|Stage IV Squamous Cell Lung Carcinoma AJCC v7
Interventions: DRUG: Docetaxel|OTHER: Laboratory Biomarker Analysis|DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sarcopenia on Clinical Outcome of Total Knee Arthroplasty
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Arm I (Sarcopenia)|PROCEDURE: Arm II(Normal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Position Sense, Force Control and Pain Intensity in Basal Thumb Osteoarthritis
Status: COMPLETED
Conditions: Thumb Osteoarthritis|Proprioceptive Disorders|Pain, Chronic
Interventions: OTHER: Active Excersises|OTHER: Reeducation ADL|OTHER: Joint protection|OTHER: Proprioception exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HECTHOR: Humira to Spare Steroids in Giant Cell Arteritis
Status: COMPLETED
Conditions: Giant Cell Arteritis
Interventions: DRUG: adalimumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Electrical Stimulation With Rowing as Exercise After Spinal Cord Injury
Status: UNKNOWN
Conditions: Spinal Cord Injury|Paraplegia|Tetraplegia
Interventions: DEVICE: Functional electrical stimulation rowing (Odstock 4 channel neuromuscular stimulator with Concept 2 Rower)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessing the da Vinci® Robotic Surgical System for Surgery of the Upper Aerodigestive Tract
Status: TERMINATED
Conditions: Hypopharyngeal Neoplasms|Laryngeal Neoplasms|Head and Neck Cancers
Interventions: DEVICE: da Vinci Surgical Robot Platform|PROCEDURE: Transoral Robotic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Potential Therapeutic Role of Hydroxyethyl Starch and Hydrocortisone in Acute Aluminum Phosphide Poisoning
Status: COMPLETED
Conditions: Potential Therapeutic Role
Interventions: DRUG: Hydroxyethyl Starch 130-0.4 60 MG/ML [Voluven]|DRUG: Hydrocortisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Deep Regional Hyperthermia in Patients With Anal Carcinoma Treated by Standard Radiochemotherapy
Status: UNKNOWN
Conditions: Anal Carcinoma
Interventions: RADIATION: Irradiation|DRUG: Mitomycin C|DRUG: 5-Fluorouracil|PROCEDURE: Hyperthermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Outcomes of Concomitant Transcatheter Aortic Valve Implantation and Off-pump Coronary Artery Bypass Grafting in Management of Severe Symptomatic Aortic Stenosis and Coronary Artery Disease
Status: UNKNOWN
Conditions: Aortic Valve Disease|Coronary Artery Disease
Interventions: PROCEDURE: TAVI and Off pump CABG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Drug Treatment for Alcoholics With Bipolar Disorder
Status: COMPLETED
Conditions: Alcoholism|Bipolar Disorder
Interventions: DRUG: sodium valproate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phrenic Nerve Infiltration in Neck Pain
Status: RECRUITING
Conditions: Chronic Neck Pain
Interventions: DRUG: Bupivacaine|OTHER: Placebo (physiological saline serum infiltration)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Impact of Reactogenicity on Quality of Life (QoL), After Administration of GlaxoSmithKline (GSK) Biologicals' Candidate Herpes Zoster Subunit (HZ/su) Vaccine (GSK1437173A) in Adults ≥ 50 Years of Age
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: GSK Biologicals Herpes Zoster subunit (HZ/su) vaccine (GSK 1437173A)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: HF vs NIV in Acute Cardiogenic Pulmonary Edema
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Edema Cardiac Cause
Interventions: PROCEDURE: NPPV/HFNC|PROCEDURE: HFNC/NPPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing 3 Different Types of Pain Blocks After Laparoscopic Nephrectomy
Status: COMPLETED
Conditions: Nephrectomy
Interventions: PROCEDURE: Transverses Abdominis Plane (TAP) block|PROCEDURE: Quadratus Lumborum (QL) block|PROCEDURE: Surgeon Infiltration using Exparel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Safety and Efficacy of rFVIIIFc in the Prevention and Treatment of Bleeding Episodes in Previously Treated Participants With Hemophilia A
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: rFVIIIFc
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of KRAS/BRAF Mutational Status With Conventional Techniques and Plasma Samples Analysis
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: OTHER: Plasma Analysis of circulating cell free DNA|OTHER: Tumor tissue analysis of circulating cell free DNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of High-intensity Laser in Jaccoud's Arthropathy in Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Musculoskeletal Diseases|Skin Diseases
Interventions: DEVICE: high-intensity laser Device.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: taVNS or TMS or Both for Depression
Status: RECRUITING
Conditions: Depression
Interventions: DEVICE: Vagus Nerve Stimulation|DEVICE: Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Nocturnal Light Exposure on the Impairment of Glucose Tolerance Induced by Chronic Sleep Restriction
Status: ACTIVE_NOT_RECRUITING
Conditions: Glucose Intolerance|Sleep Deprivation|Sleep
Interventions: OTHER: Artificial Light At Night|BEHAVIORAL: Sleep Restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Onvansertib in Combination With Either Low-dose Cytarabine or Decitabine in Adult Patients With Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Onvansertib|DRUG: Cytarabine|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Pharmacokinetics of A Modified Release Formulation of PF-06650833 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06650833|DRUG: PF-06650833|DRUG: PF-06650833|DRUG: PF-06650833|DRUG: PF-06650833|DRUG: PF-06650833
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial to Determine the Efficacy of Sculptra™ Dermal Filler for the Correction of Contour Deformities Caused by Lipoatrophy
Status: WITHDRAWN
Conditions: Lipodystrophy|Emaciation
Interventions: DEVICE: Sculptra Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Diclofenac Capsules to Treat Dental Pain
Status: COMPLETED
Conditions: Dental Pain
Interventions: DRUG: Diclofenac Test (lower dose)|DRUG: Diclofenac Test (upper dose)|DRUG: Celecoxib 400 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
Status: SUSPENDED
Conditions: Chronic Pancreatitis|Inflammatory Bowel Diseases|Hepatitis|NASH - Nonalcoholic Steatohepatitis|Acute Pancreatitis|Rheumatoid Arthritis|Diabetes Mellitus|Dyslipidemias|Multiple Sclerosis|Irritable Bowel Syndrome|Chronic Pain|Chronic Disease|Chronic Kidney Diseases|Crohn Disease|Celiac Disease|Biliary Cirrhosis|Bile Acid Synthesis Defect|Gastritis|Cholecystitis|Cholelithiases|IPMN|Cyst Pancreas|Cystic Fibrosis|Pancreatic Exocrine Insufficiency|Diarrhea Chronic|Constipation - Functional|Constipation Chronic Idiopathic
Interventions: OTHER: venipuncture|BEHAVIORAL: Questionnaires|OTHER: Additional Sample Collections
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I, Open Label,Crossover Food-Effect and Absolute Bioavailability Study of WCK2349 and WCK771 in Healthy Adult Human Volunteers
Status: COMPLETED
Conditions: Effect of Food
Interventions: DRUG: Oral WCK2349|DRUG: IV WCK771
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Diclofenac Patch for Treatment of Mild to Moderate Tendonitis or Bursitis
Status: COMPLETED
Conditions: Rotator Cuff Tendonitis|Bicipital Tendonitis|Subdeltoid Bursitis of the Shoulder|Subacromial Bursitis of the Shoulder|Medial Epicondylitis of the Elbow|Lateral Epicondylitis of the Elbow|DeQuervain's Tenosynovitis of the Wrist
Interventions: DRUG: diclofenac sodium|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation (rTMS) and P50 Evoked Potential Component
Status: COMPLETED
Conditions: Depression|Schizophrenia
Interventions: PROCEDURE: high-frequency of repetitive transcranial magnetic stimulation (rTMS)|PROCEDURE: low frequency of repetitive transcranial magnetic stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Robotic vs. Open NSM for Early Stage Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer Female|Breast Cancer|Breast Cancer, Early-Onset|Breast Disease|Breast
Interventions: DEVICE: Robotic NSM|PROCEDURE: Open NSM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INdividualized ITI Based on Fviii(ATE) Protection by VWF
Status: TERMINATED
Conditions: Hemophilia A With Inhibitor|Hemophilia A
Interventions: DRUG: Wilate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Application of Bovine Basic Fibroblast Growth Factor Gel in the Treatment of Sensitive Skin
Status: RECRUITING
Conditions: Sensitive Skin
Interventions: DRUG: bFGF|DRUG: Bovine Basic Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Allergen BioCube (ABC) Study Evaluating the Onset of Action of Fluticasone Furoate Nasal Spray and Olopatadine Nasal Spray Compared to Placebo
Status: WITHDRAWN
Conditions: Allergic Rhinitis
Interventions: DRUG: Fluticasone Furoate Nasal Spray|DRUG: Olopatadine Nasal Spray|DRUG: Saline Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adapting the Finding Respect and Ending Stigma Around HIV (FRESH) Intervention for the Dominican Republic
Status: COMPLETED
Conditions: Hiv
Interventions: BEHAVIORAL: Finding Respect and Ending Stigma around HIV (FRESH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics of Repeat Oral Doses of Dabrafenib and the Combination of Dabrafenib and Trametinib in Chinese Subjects With Melanoma
Status: WITHDRAWN
Conditions: Melanoma
Interventions: DRUG: Dabrafenib|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label Study to Assess the Efficacy and Safety of Satralizumab in Duchenne Muscular Dystrophy
Status: NOT_YET_RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Satralizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Pharmacokinetic Characteristics of Lodivixx Tab. 5/160mg in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Male Subjects
Interventions: DRUG: Exforge tab. 10/160mg|DRUG: Lodivixx tab. 5/160mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Study Evaluating Safety and Efficacy of Tigecycline Versus Imipenem/Cilastatin Subjects With Hospital-Acquired Pneumonia
Status: TERMINATED
Conditions: Pneumonia, Bacterial
Interventions: DRUG: tigecycline|DRUG: tigecycline|DRUG: imipenem/cilastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Preliminary Safety and Efficacy of the ARC Therapy Using the ARC-IM Lumbar System to Support Mobility in People With Chronic Spinal Cord Injury (BoxSwitch)
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Procedure/Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Luteal Phase After GnRHa Trigger - a Proof of Concept Study
Status: COMPLETED
Conditions: Progesterone Levels|Infertility
Interventions: DRUG: hCG(r-hCG, Ovitrelle, Merck-Serono, Hellerup, Denmark) in the late follicular phase + luteal phase|DRUG: hCG(r-hCG, Ovitrelle,Merck-Serono, Hellerup, Denmark) in the follicular phase + luteal phase|DRUG: LH(r-LH,Luveris, Merck-Serono, Hellerup, Denmark) in the luteal phase|DRUG: vaginal progesterone(Crinone; Merck-Serono, Hellerup, Denmark) and estradiol(Estrofem; Novo Nordisk, Copenhagen, Denmark) in the luteal phase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy and Chemotherapy, With or Without Cetuximab, Followed by Surgery in Treating Patients With Locally Advanced Esophageal Cancer That Can Be Removed by Surgery
Status: COMPLETED
Conditions: Adenocarcinoma of the Gastroesophageal Junction|Esophageal Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: cisplatin|DRUG: docetaxel|PROCEDURE: adjuvant therapy|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Open and Closed Chain Exercises in Athletes With Patellofemoral Pain Syndrome
Status: RECRUITING
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Open kinetic chain exercises|OTHER: Closed kinetic chain exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dry Needling Versus Ozone in Myofascial Pain Syndrome
Status: NOT_YET_RECRUITING
Conditions: Dry Needling|Ozone|Trapezius|Trigger Point Pain, Myofascial|Myofascial Pain Syndrome
Interventions: PROCEDURE: Dry Needling|PROCEDURE: Ozone Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Treatment Protocol of Daclatasvir (BMS-790052) in Combination With Sofosbuvir for the Treatment of Post-Liver Transplant Subjects With Chronic Hepatitis C
Status: NO_LONGER_AVAILABLE
Conditions: Chronic Hepatitis C
Interventions: DRUG: Daclatasvir (BMS-790052)|DRUG: Sofosbuvir
Study Type: EXPANDED_ACCESS
Clinical trial: Evaluation of Outcomes of Coronary Artery Bypass Grafting.
Status: RECRUITING
Conditions: Ischemic Heart Disease|Coronary Artery Bypass Grafting
Interventions: PROCEDURE: On-pump CABG.|PROCEDURE: Off-pump CABG.|PROCEDURE: Pump-assisted CABG.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Digital Navigation Enhances Cervical Pedicle Screw Placement Accuracy and Safety
Status: UNKNOWN
Conditions: Cervical Spine Fracture
Interventions: DEVICE: Partial cervical lamina excision group|DEVICE: Pipeline-dredge discharge group|DEVICE: Digital navigation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: St. PETERsburg Pain and Alcohol Intervention With Naltrexone and Gabapentin
Status: COMPLETED
Conditions: Chronic Pain|Alcohol Use, Unspecified|HIV Infections
Interventions: DRUG: Low-dose naltrexone|DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lesser Toe PIP Joint Arthrodesis Versus Resection Arthroplasty
Status: COMPLETED
Conditions: Claw Toe|Lesser Toe Deformity
Interventions: PROCEDURE: Arthrodesis|PROCEDURE: Resection arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: HFNO Combined With NPA Reduces Hypoxia During Sedated Gastrointestinal Endoscopy In Obese Patients
Status: UNKNOWN
Conditions: Gastric Cancer|Gastric Ulcer|Intestinal Cancer|Intestinal Polyps
Interventions: DEVICE: High-flow nasal oxygenation combined with nasopharyngeal airway|DEVICE: Regular nasal cannula combined with nasopharyngeal airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intra-pleural Administration of GL-ONC1, a Genetically Modified Vaccinia Virus, in Patients With Malignant Pleural Effusion: Primary, Metastases and Mesothelioma
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer
Interventions: BIOLOGICAL: GL-ONC1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Herbal-Based De-Pigmenting System
Status: COMPLETED
Conditions: Melasma|Hyperpigmentation
Interventions: OTHER: Herbal depigmenting agent (Epionce)|DRUG: Hydroquinone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigational Study of Psychological Intervention in Recipients of Lung Transplant (INSPIRE)
Status: COMPLETED
Conditions: Lung Diseases|Depression
Interventions: BEHAVIORAL: Telephone-based coping skills/stress management|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET/CT Imaging to Evaluate Cardiac Radiation Damage in Patients With Lung or Esophageal Cancer, EUCLID Trial
Status: RECRUITING
Conditions: Lung Carcinoma|Esophageal Carcinoma
Interventions: OTHER: Fludeoxyglucose F-18|PROCEDURE: Positron Emission Tomography|PROCEDURE: Computed Tomography|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of INV-102 Ophthalmic Solution in Adults With Moderate to Severe Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: INV-102|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: This Study Uses Ultrasound to Determine Whether Atorvastatin or Pravastatin Effects the Progression of Coronary Plaque.
Status: COMPLETED
Conditions: Coronary Arteriosclerosis
Interventions: DRUG: Atorvastatin|DRUG: Pravastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Resveratrol Supplementation on Inflammation and Cognitive Performance in Healthy Adults
Status: COMPLETED
Conditions: Cognitive Change|Mood|Systemic Inflammation
Interventions: DIETARY_SUPPLEMENT: Resveratrol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Intranasal Sufentanil Versus Intravenous Morphine for the Management of Acute Pain
Status: UNKNOWN
Conditions: Acute Pain
Interventions: DRUG: Sufentanil|DRUG: Normal saline|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Modified Positive Airway Pressure Device to Treat Sleep Disordered Breathing
Status: TERMINATED
Conditions: Sleep Apnea, Obstructive|Obesity Hypoventilation Syndrome
Interventions: DEVICE: Fisher & Paykel Healthcare PAP Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Healthy Habits for Hospitalized Older Adults to Optimize Rehabilitation
Status: RECRUITING
Conditions: Insomnia|Pain|Osteoarthritis, Knee|Osteoarthritis, Hip
Interventions: BEHAVIORAL: Healthy Habits|BEHAVIORAL: Sleep Habits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EuroPainClinicsStudy XIr-Zj
Status: ACTIVE_NOT_RECRUITING
Conditions: Back Pain
Interventions: PROCEDURE: Lumbar medial branch cryo ablation neurotomy|PROCEDURE: Lumbar medial branch radiofrequency ablation neurotomy|PROCEDURE: Endoscopic denervation of fazet joint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Anti-Inflammatory Drug and Endothelial Function
Status: UNKNOWN
Conditions: Cardiovascular Diseases|Endothelial Dysfunction|Sleep Apnea|Atherosclerosis|Coronary Artery Disease
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anxiety and Recurrent Abdominal Pain in Children
Status: COMPLETED
Conditions: Abdominal Pain|Anxiety
Interventions: DRUG: Citalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Albumin Bound-Paclitaxel for Treatment of Recurrent or Metastatic Head and Neck Cancer With Cetuximab
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DRUG: Abraxane|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palliation of Gastric Outflow Obstruction in Case of Concomitant Biliary Obstruction.
Status: UNKNOWN
Conditions: Malignant Biliary Obstruction
Interventions: PROCEDURE: EUS-CD|PROCEDURE: EUS-GEA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcranial Direct Current Stimulation in Refractory Chronic Migraine and Medication-overuse Headache
Status: UNKNOWN
Conditions: Chronic Migraine|Medication Overuse Headache
Interventions: DEVICE: Anodal transcranial direct current stimulation|DEVICE: Sham transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing SB5 to Humira® in Subjects With Moderate to Severe Rheumatoid Arthritis Despite Methotrexate Therapy
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Humira (adalimumab)|DRUG: SB5 (proposed biosimilar to adalimumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Chronic-Dose Safety and Efficacy Study of Albuterol Multi-Dose Dry Powder Inhaler in Pediatric Asthmatics
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Albuterol MDPI|DRUG: Placebo|DRUG: ProAir HFA inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Sternal Closure With Sternalock® Blue Versus Steel Wire Submitted To Bilateral Anterior Transsternal Thoracotomy (Clamshell) For Bilateral Lung Transplant
Status: UNKNOWN
Conditions: Lung|Lung Transplant
Interventions: DEVICE: Rigid plate X steel wires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Retinal Vascular Changes With and Without ILM Peeling in Diabetic Vitrectomy Using OCT-A.
Status: COMPLETED
Conditions: Diabetic Vitreous Hemorrhage|Tractional Retinal Detachment
Interventions: DIAGNOSTIC_TEST: optical coherence tomography angiography|DIAGNOSTIC_TEST: spectral domain optical coherence tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cast Immobilization for Non-Displaced Scaphoid Fractures
Status: COMPLETED
Conditions: Non-displaced Scaphoid Fractures
Interventions: DEVICE: Cast that immobilizes the thumb|DEVICE: Cast that does not immobilize the thumb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect on Glucose Control and Safety and Tolerability of LY2148568 In Japanese Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: exenatide (LY2148568)|DRUG: exenatide (LY2148568)|DRUG: exenatide (LY2148568)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Basic Carbohydrate Counting Versus Standard Outpatient Nutritional Education in Type 2 Diabetes
Status: COMPLETED
Conditions: Type2 Diabetes|Diabetes Mellitus, Type 2|Glucose Metabolism Disorders
Interventions: BEHAVIORAL: Standard nutritional education|BEHAVIORAL: Basic carbohydrate counting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastric Bypass Stent Small-Sample-Size Study For Nonalcoholic Fatty Liver Disease
Status: RECRUITING
Conditions: Nonalcoholic Fatty Liver Disease
Interventions: DEVICE: Gastric Bypass Stent System in Treatment of Patients with Nonalcoholic Fatty Liver Disease
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease
Status: SUSPENDED
Conditions: COVID-19
Interventions: DRUG: nirmatrelvir|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resiliency Training for Adolescents With Craniofacial Conditions and Their Caregivers
Status: WITHDRAWN
Conditions: Craniofacial Abnormalities
Interventions: BEHAVIORAL: SMART-3RP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Injectable Fentanyl in Sublingual Route Versus Oral Morphine Syrup for Breakthrough Pain
Status: COMPLETED
Conditions: Pain, Breakthrough
Interventions: DRUG: Fentanyl Citrate 50Mcg/Ml Inj_#1|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: sPLA2 Inhibition to Decrease Enzyme Release After PCI Trial
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Varespladib (A-002)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TCAD vs. Monotherapy for Influenza A in Immunocompromised Patients
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: TCAD|DRUG: Zanamivir or Oseltamivir|OTHER: Open label treatment with TCAD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Air Pollution on the Cognitive Function of Adolescents
Status: COMPLETED
Conditions: Attention Impaired|Risk-Taking|Risk Behavior|Social Preferences|Decision Making|Attention
Interventions: OTHER: Purifying the air with a Pure Airbox device (Zonair 3D)|OTHER: Using a sham air purifier (same device without filters)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION