pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Monocyte Chemotactic Protein-1 (MCP-1) Expressing Monocytes to Predict Preterm Delivery: PhenoMAP Study
Status: COMPLETED
Conditions: Preterm Labour
Interventions: BIOLOGICAL: biological samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Halt Growth of Liver Tumors From Uveal Melanoma With Closure of Liver Artery Following Injection of GM-CSF
Status: COMPLETED
Conditions: Uveal Melanoma|Liver Metastases
Interventions: DRUG: GM-CSF|PROCEDURE: Embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcome After Plate Osteosynthesis of Proximal Humerus Fractures Using Continous Passive Motioning Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Proximal Humerus Fracture
Interventions: DEVICE: Continuous passive motion therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Amino Acid L-Theanine on Alertness and Vigilance
Status: COMPLETED
Conditions: Theanine, (L)-Isomer
Interventions: DIETARY_SUPPLEMENT: L-theanine capsule|DIETARY_SUPPLEMENT: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Cetirizine 1% vs Minoxidil 5% Gel in Treatment of Androgenetic Alopecia
Status: UNKNOWN
Conditions: Androgenetic Alopecia
Interventions: DRUG: Cetirizine|DRUG: Minoxidil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pretargeted Radioimmunotherapy in Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Antibody TF2|DRUG: 90-Y-IMP-288|DRUG: 111-In-IMP-288
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Gene-Modified HIV-Protected Stem Cell Transplant in Treating Patients With HIV-Associated Lymphoma
Status: WITHDRAWN
Conditions: AIDS-Related Hodgkin Lymphoma|AIDS-Related Non-Hodgkin Lymphoma|HIV Infection|Recurrent Hodgkin Lymphoma|Recurrent Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: Gene-Modified HIV-Protected Hematopoietic Stem Cells|OTHER: Laboratory Biomarker Analysis|OTHER: Transplant Conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimal Alveolar Concentration of Sevoflurane Inducing Isoelectric Electroencephalogram
Status: COMPLETED
Conditions: Middle Aged Patients|Sevoflurane|General Anesthesia
Interventions: DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the CooperVision, Inc. Fanfilcon A and Enfilcon A Daily Wear Contact Lenses When Used for Frequent Replacement for up to One (1) Month of Daily Wear
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: fanfilcon A (test)|DEVICE: enfilcon A (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Effectiveness of Supportive Parents - Coping Kids
Status: RECRUITING
Conditions: Conduct Problems|Anxiety Symptoms|Depressive Symptoms
Interventions: BEHAVIORAL: Behavioral parent or child directed intervention|BEHAVIORAL: Supportive Parents - Coping Kids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Symphony: The Implantable Counter Pulsation Device (CPD) Safety and Feasibility Trial
Status: UNKNOWN
Conditions: Chronic Heart Failure
Interventions: DEVICE: Symphony|PROCEDURE: The operative approach is limited to an infraclavicular incision similar to that used for placement of a pacemaker
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ofatumumab Plus Bendamustine in Frontline and Relapsed Chronic Lymphocytic Leukaemia (CLL)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia (CLL)|Leukaemia, Lymphocytic, Chronic
Interventions: BIOLOGICAL: Ofatumumab|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of Evogliptin 5mg and Glimepiride 4mg
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: DRUG: Evogliptin→Evogliptin+Glimepiride→Glimepiride|DRUG: Glimepiride→Evogliptin→Evogliptin+Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Multiple Ascending High Dose Pharmacology Study of Anaprazole in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Anaprazole Sodium enteric-coated tablet|DRUG: Placebo|DRUG: Active controlled (rabeprazole)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Levetiracetam Versus Oxcarbazepine as Monotherapy to Evaluate Efficacy and Safety in Subjects With Newly or Recently Diagnosed Partial Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Levetiracetam|DRUG: Oxcarbazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of GDC-0941 in Patients With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma for Which Standard Therapy Either Does Not Exist or Has Proven Ineffective or Intolerable
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma, Solid Cancers
Interventions: DRUG: GDC-0941
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib for the Treatment of Chronic Graft Versus Host Disease
Status: RECRUITING
Conditions: Recurrent Moderate-Severe Chronic Graft Versus Host Disease|Hematopoietic and Lymphoid Cell Neoplasm
Interventions: DRUG: Acalabrutinib|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbial Transplantation and Vedolizumab Treatment of Crohn's Disease
Status: UNKNOWN
Conditions: Crohn Disease|Microbial Substitution
Interventions: OTHER: Fecal microbial transplantation|OTHER: Placebo capsuls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electroencephalography (EEG) Biomarkers of Response in Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: venlafaxine (Effexor)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Non-surgical Therapy With or Without Injectable Bone Putty
Status: NOT_YET_RECRUITING
Conditions: Periodontal Bone Defects
Interventions: BIOLOGICAL: Putty bone - Tricalcium phosphate with Collagen gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REmimazolam vs PrOpofol on Intraoperative hypotenSion in Major Noncardiac surgEry
Status: UNKNOWN
Conditions: Intraoperative Hypotension
Interventions: DRUG: Remimazolam|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparing the Ketogenic Effect of Coconut Oil and Different MCTs
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DIETARY_SUPPLEMENT: Coconut oil|DIETARY_SUPPLEMENT: Coconut oil + MCT|DIETARY_SUPPLEMENT: MCT|DIETARY_SUPPLEMENT: Coconut oil + tricaprylin|DIETARY_SUPPLEMENT: Tricaprylin|DIETARY_SUPPLEMENT: Tricaprin|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Prospective, Single-center, Randomized, Controlled, Open-label, Pilot Study to Compare the Effectiveness and Safety of DIuretics Add-On Strategy in Acute Decompensated Heart Failure Patients (DIOS II)
Status: WITHDRAWN
Conditions: Congestive Heart Failure
Interventions: DRUG: Furosemide|DRUG: metolazone|DRUG: furosemid/spironolactone|DRUG: metolazone/spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcranial Temporal Interference Stimulation on Risky Decision-making and Impulse Control in Gambling Disorder
Status: NOT_YET_RECRUITING
Conditions: Gambling Disorder
Interventions: DEVICE: tTIS on dACC, theta frequency (5 Hz)|DEVICE: tTIS on dACC, High frequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Two Doses of Oral Cholera Vaccine (Shanchol™) in Subjects Aged 1 Year and Older in Dominican Republic
Status: COMPLETED
Conditions: Cholera
Interventions: BIOLOGICAL: Shanchol™: Oral Cholera Vaccine Killed Bivalent (O1 and O139) Whole Cell|BIOLOGICAL: Shanchol™: Oral Cholera Vaccine Killed Bivalent (O1 and O139) Whole Cell|BIOLOGICAL: Shanchol™: Oral Cholera Vaccine Killed Bivalent (O1 and O139) Whole Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Brain Changes During Social Reward Psychotherapy for Mid- and Late-Life Suicidality
Status: RECRUITING
Conditions: Depression|Suicidal Ideation|Major Depressive Disorder|Depressive Disorder
Interventions: BEHAVIORAL: "Engage & Connect" Psychotherapy|BEHAVIORAL: Symptom Review and Psychoeducation (SRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise With Individual Dosage Against the Best Current Practice in Lower Limb Tendinopathy (MaLaGa Trial)
Status: NOT_YET_RECRUITING
Conditions: Tendinopathy
Interventions: OTHER: Best current practice exercise programme|OTHER: Experimental exercise programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Control Trial Treating Depression With Yoga and Coherent Breathing Versus Walking in Veterans
Status: TERMINATED
Conditions: Depressive Disorder, Major|Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: yoga|BEHAVIORAL: walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Australian Hepatitis and Risk Survey in Prisons
Status: RECRUITING
Conditions: Hepatitis C|Hepatitis B|HIV Infections
Interventions: DIAGNOSTIC_TEST: Point-of-care hepatitis C antibody test|DIAGNOSTIC_TEST: Point-of-care hepatitis C RNA test|DIAGNOSTIC_TEST: Point-of-care hepatitis B surface antibody test|DIAGNOSTIC_TEST: Point-of-care hepatitis B surface antigen test|DIAGNOSTIC_TEST: Point-of-care HIV antibody test|BEHAVIORAL: Interview-style survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: For Easy, Fast and Comfortable Colonoscopy, Which Position
Status: UNKNOWN
Conditions: Colonic Diseases, Functional|Prone Position|Endoscopy
Interventions: DEVICE: left position|DEVICE: left supine position|DEVICE: dynamic position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Vaccination With Autologous Dendritic Cells Loaded With Autologous Tumor Lysate or Homogenate Combined With Immunomodulating Radiotherapy and/or Preleukapheresis IFN-alfa in Patients With Metastatic Melanoma: a Randomized "Proof-of-principle" Phase II Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Melanoma of Skin Stage III|Malignant Melanoma of Skin Stage IV
Interventions: OTHER: arm 1: DC Vaccine + RT|OTHER: arm 2: DC Vaccine + IFN-alfa|OTHER: arm 3: both arm 1 and 2 + RT|BIOLOGICAL: arm 4: DC Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cadonilimab Combined With Liposomal Irinotecan Plus Leucovorin and Fluorouracil for Advanced Cholangiocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Cholangiocarcinoma
Interventions: COMBINATION_PRODUCT: Cadonilimab Combined With Liposomal Irinotecan Plus Leucovorin and Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet-rich Fibrin and Connective Tissue Graft in Recession Treatment
Status: COMPLETED
Conditions: Gingival Recession
Interventions: BIOLOGICAL: platelet-rich fibrin|PROCEDURE: connective tissue graft|PROCEDURE: coronally advanced flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DLL3-Directed Chimeric Antigen Receptor T-cells in Subjects With Extensive Stage Small Cell Lung Cancer
Status: RECRUITING
Conditions: Small Cell Lung Cancer Extensive Stage|Large Cell Neuroendocrine Carcinoma of the Lung
Interventions: BIOLOGICAL: LB2102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial to Evaluate Safety and Immunogenicity of a Dengue 1,2,3,4 (Attenuated) Vaccine
Status: UNKNOWN
Conditions: Dengue
Interventions: BIOLOGICAL: Dengue 1,2,3,4 (attenuated) vaccine|BIOLOGICAL: TetraVax-DV Vaccine - Admixture TV003|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Dose-ranging Study of Orvepitant in Patients With Chronic Refractory Cough
Status: COMPLETED
Conditions: Chronic Refractory Cough
Interventions: DRUG: Orvepitant Maleate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian Cancer
Status: COMPLETED
Conditions: Familial Ovarian Cancer|Familial Breast Cancer|BRCA1-associate Malignancies|BRCA2-associated Malignancies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate Efficacy and Safety of Glinib in Newly Diagnosed CML Patients
Status: TERMINATED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: 600mg/day of Imatinib|DRUG: 400mg/day of Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sigi Insulin Management System - A First-in-Human Study in Adults With Type 1 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Type 1 Diabetes
Interventions: DEVICE: SIGI Insulin Management System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Predictors of Treatment Failure Among Patients With Gunshot Wounds and Post-traumatic Stress Disorder
Status: COMPLETED
Conditions: Gunshot Entry Wound
Interventions: BEHAVIORAL: Mississippi Scale for Combat-Related PTSD (M-PTSD)|DIAGNOSTIC_TEST: visual analogue scale (VAS)|DIAGNOSTIC_TEST: Douleur Neuropathique 4 questions (DN4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Promoting Awareness Fetal Movements to Reduce Fetal Mortality Stillbirth, a Stepped Wedge Cluster Randomised Trial.
Status: COMPLETED
Conditions: Decreased Fetal Movements Affecting Care of Mother|Pregnancy|Stillbirth
Interventions: OTHER: A package of interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Magnetic Brain Stimulation in the Treatment of Mild Cognitive Impairment
Status: SUSPENDED
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation|DEVICE: Sham Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Magnesium Alginate in Infants With Gastroesophageal Reflux.
Status: COMPLETED
Conditions: Gastro Esophageal Reflux
Interventions: DIETARY_SUPPLEMENT: Mg alginate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Epidural Initiation Volumes
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: 5 mL epidural initiation volume (bupivacaine + fentanyl)|DRUG: 10 mL epidural initiation volume (bupivacaine + fentanyl)|DRUG: 20 mL epidural initiation volume (bupivacaine + fentanyl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double-layer Versus Purse Uterine Closure Techniques : Impact on Residual Myometrial Thickness After Cesarean
Status: COMPLETED
Conditions: Uterine Scar Defect
Interventions: PROCEDURE: Double layer closure of the hysterotomy|PROCEDURE: Purse closure of the hysterotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Viability of Short Stems in Total Hip Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis of Hip
Interventions: DEVICE: Taperloc standard length stem|DEVICE: Taperloc short length stem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A New POP (Pelvic Organ Prolapse) Scoring System: Validity and Reliability
Status: RECRUITING
Conditions: Pelvic Organ Prolapse|Prolapse|Prolapse, Vaginal|Prolapse Uterus|Prolapse; Cervix
Interventions: DIAGNOSTIC_TEST: Prolapse scoring system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Origin to Insertion Kinesio Tapping vs Non-Directional Kinesio Tapping on Quadriceps Peak Torque
Status: COMPLETED
Conditions: Quadriceps Muscle Atrophy
Interventions: OTHER: Cura Kensio-tapping|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Randomized, Double-blind, Placebo-controlled Study on the Efficacy and Safety of CVT-E002 in the Treatment of Upper Respiratory Tract Infections in a Pediatric (3-11 Years) Population
Status: COMPLETED
Conditions: Upper Respiratory Tract Infections
Interventions: OTHER: North American ginseng|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Investigate the Effect of Gemfibrozil or Rifampicin on Blood Concentrations of Selexipag in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Selexipag|DRUG: Gemfibrozil|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Comparison of Lantus and Neutral Protamine Hagedorn (NPH) Insulin in the Dawn Phenomenon
Status: COMPLETED
Conditions: Type 1 Diabetes|Dawn Phenomenon
Interventions: DRUG: Lantus (glargine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Inelastic and Elastic Lumbosacral Orthoses on Low Back Pain Prevention in Hospital Nurses
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DEVICE: QUIKDRAW Pro, Aspen Medical Products|DEVICE: MUELLER 4581, Mueller Sports Medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Artificial Intelligence Identified Dyskalemia Using Electrocardiogram (AIDE)
Status: COMPLETED
Conditions: Hyperkalemia|Hypokalemia
Interventions: OTHER: Artificial Intelligence identified Dyskalemia using Electrocardiogram (AIDE) system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effects of Hazelnuts and Cocoa on Metabolic Parameters and Vascular Reactivity
Status: COMPLETED
Conditions: Cardiovascular Diseases|Glucose Metabolism Disorders
Interventions: DIETARY_SUPPLEMENT: Hazelnut|DIETARY_SUPPLEMENT: Cocoa|DIETARY_SUPPLEMENT: No hazelnuts / No cocoa|DIETARY_SUPPLEMENT: Cream|DIETARY_SUPPLEMENT: Snack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Gemcitabine With Antiangiogenic Peptide Vaccine Therapy in Patients With Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: VEGFR2-169 and gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ipsilateral Peripheral Intravenous Access Procedures (The iPIVAP Study)
Status: COMPLETED
Conditions: Breast Cancer|Melanoma|Thoracic Cancer|Lymphedema of Upper Arm
Interventions: OTHER: Ipsilateral peripheral IV insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pediatric Longitudinal Cohort Study of Chronic Pancreatitis
Status: COMPLETED
Conditions: Pancreatitis, Chronic|Pancreatitis, Acute
Interventions: DIAGNOSTIC_TEST: Blood sample|BEHAVIORAL: Patient questionnaires|DIAGNOSTIC_TEST: Saliva sample|DIAGNOSTIC_TEST: Urine sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Synbiotic, Prebiotics and Probiotics in Children With Cerebral Palsy and Constipation
Status: COMPLETED
Conditions: Cerebral Palsy|Chronic Constipation
Interventions: BIOLOGICAL: agave inulin|BIOLOGICAL: Lactobacillus reuteri DSM 17938|OTHER: maltodextrin|OTHER: Oil mix (medium chain triglycerides and sunflower oil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Armeo Spring Pediatric in Obstetric Brachial Plexus Injury
Status: COMPLETED
Conditions: Brachial Plexus Neuropathies|Brachial Plexus Birth Palsy
Interventions: DEVICE: Armeo Spring Pediatric|OTHER: Conventional physical and occupational therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study of the Effects of Desloratadine (Aerius.) Treatment on the Quality of Life of Patients With Chronic Idiopathic Urticaria (Study P02540)
Status: COMPLETED
Conditions: Urticaria
Interventions: DRUG: Desloratadine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Defect, Congenital Heart|Heart Septal Defects, Atrial|Heart Septal Defects, Ventricular|Endocardial Cushion Defects
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized RT +/- Lapatinib for Advanced Solid Tumor Cancer Patients Receiving Radiation Therapy for Metastatic Disease
Status: TERMINATED
Conditions: Epithelial Cancer
Interventions: DRUG: Lapatinib|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Safety, and Tolerability of Methylnaltrexone in Volunteers With Impaired Hepatic Function
Status: COMPLETED
Conditions: Liver Dysfunction
Interventions: DRUG: SC Methylnaltrexone (MNTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chickpea Pulao Using Fenugreek Seeds and Indian Rennet for Improving Blood Glycaemic Levels
Status: COMPLETED
Conditions: Glucose Metabolism Disorders (Including Diabetes Mellitus)
Interventions: DIETARY_SUPPLEMENT: Fenugreek Seeds and Indian Rennet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Attentional Focus Influence During Cranio-Cervical Flexion Test
Status: COMPLETED
Conditions: Neck; Anomaly|Muscle Weakness|Muscle Weakness Condition
Interventions: OTHER: Internal Focus of Attention|OTHER: External Focus of Attention|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Combination of Sperm Selection by IMSI and Hyaluronic Acid Binding Assay May Improve ICSI Outcome.
Status: ACTIVE_NOT_RECRUITING
Conditions: Fertility Issues
Interventions: PROCEDURE: Sperm selection by IMSI|PROCEDURE: Sperm selection by IMSI and spermslow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical and Radiological Results in Robotic Assisted Knee Prosthetic Surgery With ROSA® Knee System
Status: UNKNOWN
Conditions: Knee Prosthetic Surgery|Robotic Assistance
Interventions: DEVICE: ROSA® System Robotic Assisted Knee Prosthetic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Vonoprazan in Children Who Have Symptomatic Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Vonoprazan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Fetoscopic Regenerative Repair of Spina Bifida - A Pilot Study
Status: UNKNOWN
Conditions: Spina Bifida|Myelomeningocele|Neural Tube Defects
Interventions: DEVICE: Minimally invasive fetoscopic repair of MMC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of A Novel Compound For Excessive Daytime Sleepiness Associated With Narcolepsy
Status: COMPLETED
Conditions: Excessive Daytime Sleepiness|Narcolepsy
Interventions: DRUG: Placebo|DRUG: PF-03654746
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation After Parathyroid Surgery
Status: COMPLETED
Conditions: Primary Hyperparathyroidism
Interventions: DRUG: cholecalciferol and calcium carbonate|DRUG: calcium carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Prulifloxacin vs Placebo in Treatment of Acute Gastroenteritis in Adult Travelers
Status: COMPLETED
Conditions: Acute Bacterial Gastroenteritis
Interventions: DRUG: prulifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Dose-escalating Study of MDT-10013 for Acute Postoperative Pain Following Total Knee Arthroplasty
Status: WITHDRAWN
Conditions: Post-operation Pain
Interventions: DRUG: MDT-10013
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caffeic Acid Tablets as a Second-line Therapy for ITP
Status: COMPLETED
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Caffeic acid|DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised Hosts
Status: RECRUITING
Conditions: Viral Infection|Hematopoietic Stem Cell Transplantation (HSCT)|Primary Immunodeficiency Disorders (PID)
Interventions: BIOLOGICAL: Norovirus -specific T-cell (NST) therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification of Explanatory Factors for the Lack of Muscle Strength Gain Following a Pulmonary Rehabilitation Program in COPD Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Voluntary activation assessed by magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Covered vs. Uncovered SEMS for Occluded Biliary Metal Stents
Status: COMPLETED
Conditions: Biliary Tract Neoplasms|Jaundice, Obstructive
Interventions: DEVICE: ComVi stent|DEVICE: Uncovered SEMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability and Pharmacokinetics of JNJ-64991524 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-64991524 Dose Level 1|DRUG: JNJ-64991524 Dose Level 2|DRUG: JNJ-64991524 Dose Level 3|DRUG: JNJ-64991524 Dose Level 4|DRUG: JNJ-64991524 Dose Level 5|DRUG: JNJ-64991524 Dose Level 6|DRUG: Placebo|DRUG: JNJ-64991524 Dose Level 7|DRUG: JNJ-64991524 Dose Level 8|DRUG: JNJ-64991524 Dose Level 9
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effects of Walkasins on Gait Speed of Individuals With Mild Cognitive Impairments
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Cognitive Decline|Gait Disorders in Old Age
Interventions: DEVICE: Walkasins
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevention of Postoperative Nausea and Vomiting (PONV) in Surgical Patients
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Dronabinol|DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pioglitazone on Portal and Systemic Hemodynamics in Patients With Advanced Cirrhosis
Status: COMPLETED
Conditions: Cirrhosis|Ascites|Portal Hypertension
Interventions: DRUG: Pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Risk and Resilience in Pulmonary Arterial Hypertension and Genetically Susceptible Individuals
Status: RECRUITING
Conditions: Idiopathic Pulmonary Arterial Hypertension|Heritable Pulmonary Arterial Hypertension|Unaffected Mutation Carriers: Healthy Participants With a Known BMPR2 Gene Mutation and Normal Pulmonary Pressure and RV Function on Echo|Healthy Individuals With no Cardiopulmonary Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Retinal Displacement Rates in Pneumatic Retinopexy Versus Pars Plana Vitrectomy For Primary Retinal Detachment
Status: UNKNOWN
Conditions: Retinal Detachment|Metamorphopsia
Interventions: PROCEDURE: PnR + laser/cryotherapy|PROCEDURE: PPV + laser/cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A(f)MAZE-CABG Study
Status: TERMINATED
Conditions: Coronary Arteriosclerosis|Atrial Fibrillation|Coronary Artery Bypass Graft Surgery
Interventions: DEVICE: HIFU AF Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Upadacitinib in Atopic Dermatitis-induced Sleep Disturbance in Adults With Moderate to Severe Atopic Dermatitis
Status: NOT_YET_RECRUITING
Conditions: Atopic Dermatitis|Sleep Disturbance
Interventions: DRUG: Upadacitinib|DRUG: Placebo for Upadacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgery Plus Sulindac or Surgery Alone for Advanced Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer|Liver Metastasis|Colorectal Adenocarcinoma
Interventions: DRUG: Sulindac|DRUG: Placebo|OTHER: Validate assays and shipping methods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a New Medical Device AL539 in Patients With Obstructive Apneas Sleep Syndrome
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DEVICE: AL539 (SRETT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of a Single Colecalciferol Dose on Insulin Resistance
Status: UNKNOWN
Conditions: Insulin Resistance|Glucose Intolerance
Interventions: DRUG: Colecalciferol (Vitamin D3) 300.000 UI|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: What Needle Diameter Should Physician Use When They Perform Lumbar Puncture ? A Randomized Controlled Trial
Status: COMPLETED
Conditions: Post-lumbar Puncture Headache|Backache
Interventions: DEVICE: whitacre 24 gauge|DEVICE: whitacre 22 gauge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prevalence and Risk Evaluation of Diabetic Complications of the Foot in A Large Canadian Population
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Diabetes Mellitus, Type 1|Foot Deformities|Onychauxis|Neuropathy, Diabetic|Hyperkeratosis|Onychomycosis|Foot Ulcer, Diabetic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chlorhexidine Mouthrinse Before EBUS-TBNA
Status: COMPLETED
Conditions: Endobronchial Ultrasound
Interventions: DRUG: Chlorhexidine Gluconate 0.12 % Mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Contribution of New Generation Oxford Nanopore-type High-throughput Sequencing in the Diagnostic Strategy of Neurogenetic Diseases.
Status: UNKNOWN
Conditions: Neuro-Degenerative Disease
Interventions: BIOLOGICAL: Subject carrying an amplification of nucleotide repeats in one of the following 9 genes FMR1, DMPK, ZNF9, SCA2, JPH3, HD, FXN, C9ORF72, RFC1
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Non - Incised Papilla Versus Single Flap Technique In The Reconstruction Of Intrabony Defect
Status: RECRUITING
Conditions: Periodontal Attachment Loss
Interventions: PROCEDURE: non - Incised Papilla surgical approach NIPSA for intrabony defect|PROCEDURE: single-flap approach SFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Versus Intermittent Dosing Regimens for Pomalidomide in Relapsed/Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Probiotic on Survival and Treatment Response in Metastatic Non-small Cell Lung Cancer Patients
Status: RECRUITING
Conditions: Metastatic Non-small Cell Lung Cancer
Interventions: DIETARY_SUPPLEMENT: Bifidobacterium animalis subsp. lactis Bl-04|OTHER: Plasebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biological Therapy Following Surgery in Treating Patients With Stage III or Stage IV Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: autologous tumor cell vaccine|BIOLOGICAL: muromonab-CD3|BIOLOGICAL: therapeutic autologous lymphocytes|PROCEDURE: surgical procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of INP105 (Olanzapine by I231 POD® Device) Nasal Spray in Healthy Volunteers - SNAP 101
Status: COMPLETED
Conditions: Acute Agitation
Interventions: DRUG: Zyprexa IM|DRUG: Zydis|DRUG: INP105|DEVICE: I231 POD® Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Biological Effects of Citrus-phytochemicals in Subjective Cognitive Decline.
Status: COMPLETED
Conditions: Subjective Cognitive Decline
Interventions: DIETARY_SUPPLEMENT: Extracts of citrus peels standardized in AUR and NAR (phytocomplex).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: EVALUATION OF AN INNOVATIVE TREATMENT FOR RADIOCARPAL OSTEOARTHRITIS USING INTRA-ARTICULAR INJECTION OF A MIXTURE OF AUTOLOGOUS MICROFAT AND AUTOLOGOUS PLATELET-RICH PLASMA
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: injection of microfat and plasma rich platelet PRP|DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study for Absorption of Intranasal Epinephrine Compared to Conventional Intramuscular Epinephrine
Status: COMPLETED
Conditions: Anaphylaxis
Interventions: DRUG: Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABC008 in Subjects With T-cell Large Granular Lymphocytic Leukemia (T-LGLL)
Status: RECRUITING
Conditions: T-cell Large Granular Lymphocytic Leukemia
Interventions: DRUG: ABC008
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: pRESET for Occlusive Stroke Treatment
Status: COMPLETED
Conditions: Brain Diseases|Cardiovascular Diseases|Central Nervous System Diseases|Cerebrovascular Disorders|Ischemia|Nervous System Diseases|Pathologic Processes|Stroke, Ischemic|Stroke, Acute|Vascular Diseases
Interventions: DEVICE: Mechanical Thrombectomy using the pRESET Thrombectomy device|DEVICE: Mechanical Thrombectomy using the Solitaire Revascularization Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endofaster Test for Helicobacter Pylori Detection in Patients on Proton Pump Inhibitor Therapy
Status: UNKNOWN
Conditions: Helicobacter Infections
Interventions: PROCEDURE: Gastroscopy|DEVICE: EndoFaster test|OTHER: Clo test|OTHER: Faecal Helicobacter pylori antigen
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Glutamine in Preventing Peripheral Neuropathy in Patients With Multiple Myeloma Receiving Bortezomib
Status: TERMINATED
Conditions: Chemotherapeutic Agent Toxicity|Multiple Myeloma|Peripheral Neuropathy
Interventions: DRUG: glutamine|OTHER: quality-of-life assessment|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of IASTM With and Without CT on Pain, ROM, and Functional Disability in Post-Operative Knee Stiffness Patients
Status: RECRUITING
Conditions: Pain|Pain, Postoperative|Pain, Joint|Knee Pain Chronic
Interventions: COMBINATION_PRODUCT: Instrumental Soft Tissue Mobilization Technique with Conservative Treatment|COMBINATION_PRODUCT: Conservative Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adoptive Transfer of Haplo-identical DLI for AML and MDS
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Idarubicin|DRUG: Cytarabine|BIOLOGICAL: DLI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lens Wearing Experience and Biocompatibility of a Multi-Purpose Disinfecting Solution (MPDS)
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: OPTI-FREE PureMoist multipurpose disinfecting solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bevacizumab 0.500MG Intravitreal There Isn't Lower Than 0.625MG in the Treatment of ROP Type 1
Status: UNKNOWN
Conditions: Retinopathy of Prematurity
Interventions: PROCEDURE: Injection of bevacizumab intravitreal (Avastin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IIb Clinical Study of Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10 on Healthy People Aged 18-65
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: 5μg/ml ESAT6-CFP10|BIOLOGICAL: 10μg/ml ESAT6-CFP10|BIOLOGICAL: BCG|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Comparing the Efficiency and Safety of S-CHOP(Cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated CD20(Cluster of Differentiation Antigen 20)-Positive DLBCL Patients
Status: UNKNOWN
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: SCT400 plus CHOP|DRUG: Rituximab plus CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Manual Versus Electric Vacuum Aspiration for Pregnancy Termination Between 10-14 Weeks
Status: COMPLETED
Conditions: Abortion in First Trimester
Interventions: PROCEDURE: Electric Vacuum Aspiration|PROCEDURE: Manual Vacuum Aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Pulse Electrical Stimulation Around Eye in Dry Eye Disease Patients Scheduled for LASEK Surgery
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DEVICE: Real Pulse Electrical Stimulation (NuEyne 01)|DEVICE: Sham Pulse Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Using Eggshell Calcium to Mitigate Fluorosis in Ethiopia
Status: COMPLETED
Conditions: Fluoride Poisoning|Hemoglobin|Underweight|Stunting|Development; Delayed, Mental|Fluorosis, Dental|Fluorosis; Skeletal|Zinc Deficiency
Interventions: BEHAVIORAL: Promotion of chicken eggs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vitamin D Deficiency, Insulin Resistance and FGF-23
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Ergocalciferol|DIETARY_SUPPLEMENT: Ergocalciferol placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Periscope Phase C Bordetella Pertussis Human Challenge Study With Delayed Antibiotic Therapy for 6 Weeks
Status: RECRUITING
Conditions: Pertussis/Whooping Cough
Interventions: BIOLOGICAL: Bordetella pertussis B1917|DRUG: Azithromycin Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Combination Chemotherapy Followed by Radiation Therapy in Patients With Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: ifosfamide|DRUG: mesna|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT