pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects and Mechanisms of Change of Internet Delivered Cognitive Behavior Therapy for Generalized Anxiety Disorder
Status: RECRUITING
Conditions: Generalized Anxiety Disorder
Interventions: BEHAVIORAL: Metacognitive Internet delivered Cognitive Behavior Therapy|BEHAVIORAL: Intolerance of uncertainty based Internet delivered Cognitive Behavior Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study of the Effects of Trelagliptin and Alogliptin on Glucose Variability in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Trelagliptin|DRUG: Alogliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Activity Versus Pulmonary Rehabilitation in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: BEHAVIORAL: Physical Activity Intervention|BEHAVIORAL: Pulmonary Rehabilitation Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SRT Combined With Anlotinib for the Treatment of Brain Metastases From Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-Small-Cell Lung Cancer|Brain Metastases
Interventions: DRUG: Anlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Identification of Subclinical Atherosclerosis Using Non-Invasive Imaging Research (EISNER)
Status: COMPLETED
Conditions: Atherosclerosis|Coronary Artery Disease
Interventions: OTHER: Coronary Artery Calcium (CAC) Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: RCT of Epinephrine (None, 100mcg, and 200mcg) in a Hyperbaric Bupivacaine, Fentanyl and Morphine Spinal in C-sections.
Status: WITHDRAWN
Conditions: Pregnancy|Cesarean Section
Interventions: DRUG: 100 mcg Epinephrine|OTHER: normal saline|DRUG: 200 mcg Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Biphasic Insulin Aspart 30 in Type 2 Diabetes Failing OAD Therapy
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart|DRUG: insulin glargine|DRUG: metformin|DRUG: pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Safety and Efficacy of Nitric Oxide Gel in Subjects With Pressure Sore
Status: UNKNOWN
Conditions: Pressure Ulcer
Interventions: DRUG: Nitric Oxide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: THE EFFECT OF THE EDUCATION PROGRAM BASED ON THE HEALTH BELIEF MODEL ON THE PHYSICAL ACTIVITY BELIEFS AND BEHAVIOR OF FIRST YEAR STUDENTS OF THE FACULTY OF NURSING
Status: COMPLETED
Conditions: THE HEALTH BELIEF MODEL ON THE PHYSICAL ACTIVITY BELIEFS
Interventions: OTHER: The health belief model-based exercise training program and health belief model-based education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Immunization Against Tumor Cells in Sezary Syndrome
Status: COMPLETED
Conditions: Cutaneous T-cell Lymphoma|Sezary Syndrome
Interventions: BIOLOGICAL: Autologous Dendritic Cell Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Toleration of PEP005 Topical Gel When Applied to a Treatment Area of up to 100cm2
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: PEP005 Topical gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of The Pharmacokinetics And Safety Of Voriconazole In Children 2 To Less Than 15 Years Old Who Are At High Risk For Systemic Fungal Infection
Status: COMPLETED
Conditions: Aspergillosis, Aspergilloma
Interventions: DRUG: Voriconazole|DRUG: Voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Non-inferiority Clinical Trial to Compare the Safety and Performance of MeRes100 Sirolimus-eluting BioResorbable Vascular Scaffold System Versus Contemporary DES Platforms in Patients With de Novo Coronary Artery Lesions
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: MeRes 100 Sirolimus-eluting Bioresorbable Vascular Scaffold System (BRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Relationship Between Sarcopenia and Balance, Fear of Falling and Fall Risk in Older Female Patients
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DIAGNOSTIC_TEST: valuation of balance status, fear of falling and risk of falling in patients non-sarcopenia.|DIAGNOSTIC_TEST: Evaluation of balance status, fear of falling and risk of falling in patients with probable sarcopenia.|DIAGNOSTIC_TEST: Evaluation of balance status, fear of falling and risk of falling in patients with sarcopenia.|DIAGNOSTIC_TEST: Evaluation of balance status, fear of falling and risk of falling in patients with severe sarcopenia.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acute Effect of Nitrate From Natural Dietary Sources on Arterial Stiffness and Blood Pressures in Healthy Individuals
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Spinach soup|OTHER: Asparagus soup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Hop Compounds and Immune System
Status: COMPLETED
Conditions: Inflammatory Response
Interventions: OTHER: Dietary Intervention 1: Placebo|OTHER: Dietary Intervention 2: Xanthohumol and Iso-alpha acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral Hydroxychloroquine Plus Oral Sorafenib to Treat Patients With Refractory or Relapsed Solid Tumors
Status: COMPLETED
Conditions: Refractory or Relapsed Solid Tumors
Interventions: DRUG: Sorafenib combined with Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Exercise for Learning Anger and Excitation Management
Status: COMPLETED
Conditions: Anger|Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Anger Management Therapy|BEHAVIORAL: Anger Management Therapy & RELAX app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Program AACTIVE: African Americans Coming Together to Increase Vital Exercise
Status: WITHDRAWN
Conditions: Type 2 Diabetes|Depression
Interventions: BEHAVIORAL: Cognitive behavioral therapy and physical activity sessions|BEHAVIORAL: Enhanced Usual Care + Diabetes Basics Web Series
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Lenvatinib (E7080) in Radioiodine (131 I)-Refractory Differentiated Thyroid Cancer in China
Status: COMPLETED
Conditions: Differentiated Thyroid Cancer (DTC)
Interventions: DRUG: Lenvatinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Probiotics Supplementation on Intestinal Microbiome in Malignancy Pts(Get Pelvic/Abdominal Rtx)
Status: UNKNOWN
Conditions: Cancer
Interventions: DIETARY_SUPPLEMENT: probiotics (six probiotic cultures)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect Site Controlled, Reaction Time Safeguarded, Patient Maintained Sedation With Propofol in Anxious Patients
Status: UNKNOWN
Conditions: Oral Surgical Procedures|Surgery, Oral|Dental Anxiety|Surgery|Colonoscopy
Interventions: DEVICE: Pump for propofol delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anterior Quadratus Lumborum Block Versus Erector Spinae Plane Block After Elective Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section|Postoperative Analgesia
Interventions: OTHER: Quadratus lumborum block|OTHER: erector spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Acute Treatment
Status: COMPLETED
Conditions: Binge-Eating Disorder|Obesity
Interventions: DRUG: Lisdexamfetamine Dimesylate|BEHAVIORAL: Cognitive-Behavioral Therapy|OTHER: Combination LDX and Cognitive-Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess the Safety and Effectiveness of Hyruan ONE Versus a Comparator for the Treatment of Knee Osteoarthritis in Europe
Status: COMPLETED
Conditions: Osteoarthritis (OA) of the Knee
Interventions: DEVICE: Hyruan ONE®|DEVICE: Durolane®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab (PVR) Versus Venetoclax and Rituximab (VR) in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Pirtobrutinib|DRUG: Venetoclax|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Physical Therapy on Low Back Pain, Disc Height Index, Postural Stability, Disability, Gait and Function in Persons With Postero-lateral Disc Herniation
Status: ENROLLING_BY_INVITATION
Conditions: Herniation, Disc|Low Back Pain
Interventions: OTHER: Standard medical treatment|DEVICE: Lumbar Traction|OTHER: Mckenzie Extension Protocol|DEVICE: Interferential Therapy|DEVICE: Heat Therapy|OTHER: Sustained Natural Apophyseal Glides (SNAGs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Extension Study Evaluating Safety and Efficacy of Proellex® In Women Who Have Previously Completed ZPU 003 Ext
Status: TERMINATED
Conditions: Uterine Fibroids
Interventions: DRUG: 25 mg Proellex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Subjects With GPP
Status: COMPLETED
Conditions: Generalized Pustular Psoriasis
Interventions: DRUG: Imsidolimab high dose|DRUG: Imsidolimab low dose|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Intravenous Catheter Securement With Tissue Adhesive
Status: COMPLETED
Conditions: Vascular Access Devices
Interventions: DEVICE: Standard IV dressing|DEVICE: Standard IV dressing plus a tissue adhesive peripheral IV securement device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Orally Administered BBT-401-1S in Subjects With Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: BBT-401-1S or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Implantation Enhancement by Elective Cryopreservation of All Viable Embryos
Status: COMPLETED
Conditions: Infertility|OHSS
Interventions: PROCEDURE: Vitrification with subsequent-cycle embryo thawing/transfer|PROCEDURE: Intensified luteal phase support for fresh embryo transfer|DRUG: Pregnyl®|DRUG: Utrogestan®|DRUG: Progynova®|DEVICE: CryoBioSystem®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined and Isolated Effects of Sleep Deprivation and Alcohol Intake on Exercise Performance in Humans.
Status: COMPLETED
Conditions: Alcohol Intake|Sleep Deprivation
Interventions: OTHER: Alcohol intake|OTHER: Sleep deprivation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Efficacy of Second Forward-view Examination of Left Colon for Adenoma Detection During Colonoscopy
Status: RECRUITING
Conditions: Colon Adenoma
Interventions: BEHAVIORAL: re-examination|BEHAVIORAL: extended withdraw time
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Dupilumab in Chinese Adult Participants With CRSwNP
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps
Interventions: DRUG: Dupilumab|DRUG: Placebo|DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abdominal Functional Electrical Stimulation (AFES) to Assist Ventilator Weaning in Tetraplegia
Status: COMPLETED
Conditions: Spinal Cord Injury|Tetraplegia
Interventions: DEVICE: Abdominal FES
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypnosis to Reduce Aromatase Inhibitor Pain and Improve Adherence
Status: COMPLETED
Conditions: Breast Neoplasms|Musculoskeletal Pain
Interventions: BEHAVIORAL: Hypnosis|BEHAVIORAL: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Kinesiology Taping on Head and Trunk Control in Children With Duchenne Muscular Dystrophy
Status: RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: OTHER: kinesio tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Real-time Artificial Intelligent (AI)-Assisted Muscle Ultrasound for Monitoring Muscle Mass Reduction in ICU Patients
Status: COMPLETED
Conditions: Tetanus
Interventions: DEVICE: Real-time AI-assisted muscle ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Hormone Replacement Therapy on Lupus Activity
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Conjugated equine estrogens 0.625 mg/d + MPA 5 mg/d/10d
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Doppler (TCD) Ultrasound of Subjects Enrolled in BABY HUG - Ancillary to BABY HUG
Status: COMPLETED
Conditions: Blood Disease|Anemia, Sickle Cell|Cerebrovascular Disorders|Cerebral Embolism and Thrombosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Psychological Intervention to Prevent Cardiovascular Event-Induced PTSD (REACH Sub-study)
Status: TERMINATED
Conditions: Acute Coronary Syndrome|TIA|Stroke|Cardiac Arrest|PTSD
Interventions: BEHAVIORAL: Written Exposure Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact Of Timing Of Drainage Of Massive Ascites On Operative And Post-Operative Course In Living-Donor Liver Transplant Recipients. A Prospective Randomized Controlled Trial.
Status: COMPLETED
Conditions: Massive Ascites
Interventions: PROCEDURE: ultrasound guided ascitic fluid drainage|PROCEDURE: operative drainage of ascites through small skin incision after induction of anesthesia|DEVICE: ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Compare the Pharmacokinetics and Safety of Mitapivat 100 mg Tablet Formulation With Mitapivat 2 × 50 mg Tablet Formulation in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Mitapivat tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Tolerance of Intra-vaginal Treatment With a Total Freeze-dried Culture of Lcr Regenerans® in the Prevention of Relapses of Recurrent Vulvovaginal Candidiasis
Status: COMPLETED
Conditions: Candidiasis, Vulvovaginal
Interventions: DRUG: Lcr Regenerans|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Peer Navigation and Contingency Management on Retention in HIV Care
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: BEHAVIORAL: Combined Contingency Management and Peer Navigation|BEHAVIORAL: Contingency Management|BEHAVIORAL: Peer Navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Role of Intestinal Protozoa and Helminths in the Course of Ulcerative Colitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Ulcerative Colitis|Ulcerative Colitis Exacerbation|Protozoan Infections|Helminth Infection
Interventions: DIAGNOSTIC_TEST: parasitological diagnostics (coproscopy)|DRUG: Nitazoxanide 500Mg Oral Tablet|DRUG: Mesalazine 250Mg Tablet and nitazoxanide 500Mg Oral Tablet|DRUG: Mesalazine 250Mg|DRUG: Placebo tabletes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pattern Recognition Prosthetic Control
Status: COMPLETED
Conditions: Prosthesis User|Congenital Amputation of Upper Limb|Amputation; Traumatic, Limb
Interventions: DEVICE: EMG-Pattern Recognition Controller
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrauterine Human Chorionic Gonadotropin at the Time of Embryo Transfer
Status: COMPLETED
Conditions: Control Media Only|Study hCG and Media
Interventions: OTHER: hCG at the Time of Embryo Transfer|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Stimulation in Motor Stroke Rehabilitation
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: tDCS|DEVICE: rTMS|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Azithromycin on Oesophageal Hypomotility
Status: COMPLETED
Conditions: Esophageal Motility Disorders
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Pharmacokinetics (PK), Safety and Tolerability Study of Inhaled AZD8871
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease COPD
Interventions: DRUG: AZD8871 100 µg|DRUG: AZD8871 600 µg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Troponin T in Chronic Obstructive Pulmonary Disease (COPD) Patients After Physical Exercise
Status: COMPLETED
Conditions: COPD|Myocardial Diseases
Interventions: DEVICE: Treadmill exercise test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MG Granules Improve COVID-19 Efficacy and Safety of Convalescent Exercise Tolerance
Status: NOT_YET_RECRUITING
Conditions: COVID-19
Interventions: DRUG: Manzi Guben granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Therapeutic Combination of Dronabinol and PEA for Tourette Syndrome
Status: COMPLETED
Conditions: Tourette Syndrome
Interventions: DRUG: Dronabinol and Palmitoylethanolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultralow Versus Standard Pneumoperitoneum Pressure
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: OTHER: Pneumoperitoneum Pressure 6 mmHg|OTHER: Pneumoperitoneum Pressure 15 mmHg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Use of Onexton in Moderate Acne Vulgaris for Patients With Skin of Color
Status: COMPLETED
Conditions: Acne Vulgaris|Post Inflammatory Hyperpigmentation
Interventions: DRUG: ONEXTON Topical Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: THE IMPACT- 24M TRIAL (IMPlant Augmenting Cerebral Blood Flow in Mild Strokes Trial 24 Hours From Stroke Onset)
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DEVICE: ISS SPG stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Evaluating the Safety and Efficacy of Roflumilast in Type 2 Diabetic Patients With Diabetic Neuropathy
Status: COMPLETED
Conditions: Type 2 Diabetes (Adult Onset)|Diabetic Neuropathies
Interventions: DRUG: Alpha lipoic acid|DRUG: Roflumilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capnographic Monitoring of Propofol-sedation During Colonoscopy
Status: COMPLETED
Conditions: Hypoxia
Interventions: DEVICE: Microcap (Oridion, Needham, MA, USA)|DEVICE: Smart Capno Line Plus O2 (Oridion, Needham, MA, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Enhanced Vascular Function Following Intake of Feruloyl Esterase-processed High Fibre Bread.
Status: COMPLETED
Conditions: Cardiovascular Risk Factor
Interventions: DIETARY_SUPPLEMENT: White Bread|DIETARY_SUPPLEMENT: Wholegrain bread|DIETARY_SUPPLEMENT: Wholegrain Enzyme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy Study of a Neuropsychological Rehabilitation Intervention for Children With Non-symptomatic Epilepsy
Status: UNKNOWN
Conditions: Epilepsy
Interventions: BEHAVIORAL: Home rehabilitation training|BEHAVIORAL: Home control activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Comfort and Blurring Profile Evaluation of Marketed Lubricant Eye Drops
Status: COMPLETED
Conditions: Dry Eye
Interventions: OTHER: Systane Ultra Lubricant Eye Drops|OTHER: Optive Lubricant Eye Drops|OTHER: Blink Tears|OTHER: GenTeal Moderate Lubricant Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single-dose Study to Evaluate Safety, Tolerability, and Pharmacodynamics of REMD-477 in Subjects With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Diabetes
Interventions: BIOLOGICAL: REMD-477|BIOLOGICAL: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CoQ10 and D-ribose in Patients With Diastolic Heart Failure
Status: COMPLETED
Conditions: Heart Failure, Diastolic
Interventions: DRUG: CoQ10|DRUG: D-Ribose Oral Powder|OTHER: Placebo pills|OTHER: Placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Safety, Tolerability and Pharmacokinetics With Single and Multiple Ascending Doses of AZD1446
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD1446|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immunotherapy by Nivolumab for HIV+ Patients
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer Metastatic|Non Small Cell Lung Cancer Stage IIIB|HIV/AIDS
Interventions: DRUG: Nivolumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Unresectable or Metastatic Biliary Tract or Gallbladder Cancer
Status: COMPLETED
Conditions: Extrahepatic Bile Duct Cancer|Gallbladder Cancer|Liver Cancer
Interventions: DRUG: fluorouracil|DRUG: gemcitabine hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leprosy Skin Test Antigens Trial
Status: COMPLETED
Conditions: Leprosy
Interventions: BIOLOGICAL: Tuberculin, Purified Protein Derivative|OTHER: MLSA-LAM|OTHER: MLCwA|BIOLOGICAL: Tuberculin, Purified Protein Derivative|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: An Expanded Access, Open-Label Study of Obinutuzumab (GA101) Plus Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Obinutuzumab|DRUG: Chlorambucil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nordic Study in Cardiac and Lung Transplantation: Outcome in Relation to Cyclosporine Microemulsion C2 Levels
Status: COMPLETED
Conditions: Heart and Lung Transplant
Interventions: DRUG: cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Midlines and Thrombophlebitis
Status: COMPLETED
Conditions: Catheter Infection|Catheter Thrombosis|Catheter Complications
Interventions: DEVICE: Angiodynamics BioFlo Midline Catheter|DEVICE: Teleflex Arrowg+ard Blue Advanced Midline Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alemtuzumab and Pentostatin In T-cell Neoplasms
Status: TERMINATED
Conditions: Lymphoma|Leukemia
Interventions: DRUG: Pentostatin|DRUG: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Migration of CS vs CR Insert in TKA Using RSA
Status: RECRUITING
Conditions: Wear of Articular Bearing Surface of Prosthetic Joint|Migration of Implant
Interventions: DEVICE: Condylar Stabilizing (CS) insert|DEVICE: Cruciate Retaining (CR) insert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Chemotherapy and Surgery Followed by Peripheral Stem Cell Transplantation in Treating Patients With Metastatic Neuroblastoma
Status: UNKNOWN
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: filgrastim|DRUG: busulfan|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: melphalan|DRUG: vincristine sulfate|PROCEDURE: conventional surgery|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Calcium and Vitamin D vs Markers of Adenomatous Polyps
Status: COMPLETED
Conditions: Colorectal Adenomatous Polyps
Interventions: DIETARY_SUPPLEMENT: Calcium and vitamin D3 combined|DRUG: Placebo|DIETARY_SUPPLEMENT: Calcium|DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Kegel ex's With and Without WBV on PFM Strength, Incontinence Intensity, and QOL in Patients With SUI.
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: whole body vibrator|OTHER: GROUP B Pelvic floor muscle training (PFMT) and conservative treatment.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Circumcision With a Novel Disposable Device in Chinese Children: a Hospital-based Randomized Controlled Trail
Status: COMPLETED
Conditions: Circumcision
Interventions: PROCEDURE: circumcision with Shenghuan in Yan's method|PROCEDURE: circumcision with Shenghuan in Peng's method|PROCEDURE: conventional method with incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vascular Responses to High vs Low Repetition Resistance Exercise Training in Young Men
Status: COMPLETED
Conditions: Weight-Lifting Exercise Program
Interventions: BEHAVIORAL: Lower-repetition, heavier-load|BEHAVIORAL: Higher-repetition, lighter-load
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical and Microbiological Effects of an Essential Oils Solution Used as an Adjunct to Daily Oral Hygiene Practices in Chronic Periodontitis Patients in Supportive Care
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: OTHER: Essential Oils solution|OTHER: negative control solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of CoQ10 for Mild-to-Moderate Statin-Associated Muscle Symptoms
Status: COMPLETED
Conditions: Pain|Weakness|Cramps|Myalgia or Myositis Nos|HMG COA Reductase Inhibitor Adverse Reaction
Interventions: DIETARY_SUPPLEMENT: Coenzyme Q10|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IRCI Gynae Sarcomas, High Grade Uterine Sarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Uterine Sarcoma
Interventions: DRUG: Cabozantinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Descriptive Observational Study of Patient-performed Pre-oxygenation
Status: NOT_YET_RECRUITING
Conditions: Anesthesia|ASA Physical Status I|ASA Physical Status II
Interventions: OTHER: Auto-preoxygenation|OTHER: APAIS scale|OTHER: Visual analog anxiety scale (VAS-A)|OTHER: Visual analog comfort scale (VAS-C)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Techniques Between Concave Distraction and Convex Resection in the Treatment of Congenital Cervical Scoliosis
Status: COMPLETED
Conditions: Congenital Scoliosis Due to Bony Malformation|Cervical Scoliosis
Interventions: PROCEDURE: hemivertebra resection on convex side|PROCEDURE: concave distraction group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: LMX-4 for Postoperative Pain Management in Infants and Children Undergoing Penoplasty Surgery
Status: COMPLETED
Conditions: Post-Operative Pain
Interventions: DRUG: LMX4|DRUG: LMX4 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate rhuMab 2C4 and Gemcitabine in Subjects With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Cancer
Interventions: DRUG: Placebo|DRUG: Gemcitabine|DRUG: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Veliparib and Temozolomide in Treating Patients With Recurrent Glioblastoma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: temozolomide 60 mg x 21 days|DRUG: temozolomide 75 mg x 21 days|DRUG: ABT-888 20 mg x 21 days|DRUG: ABT-888 40 mg x 21 days|DRUG: Temozolomide 150 mg x 5 days|DRUG: ABT-888 40 mg x 5 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INREAL - Nintedanib for Changes in Dyspnea and Cough in Patients Suffering From Chronic Fibrosing Interstitial Lung Disease (ILD) With a Progressive Phenotype in Everyday Clinical Practice: a Real-world Evaluation
Status: COMPLETED
Conditions: Lung Diseases, Interstitial
Interventions: DRUG: Nintedanib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Endoscopic Stenting in Crohn Related Strictures
Status: COMPLETED
Conditions: Intestinal Strictures Related to Crohn´s Disease
Interventions: PROCEDURE: Self-expandable metal stent|PROCEDURE: Balloon dilatation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of a Novel Carpal Tunnel Tissue Manipulation Device in Treating Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: Carpal Tunnel Tissue Manipulation Device (CTMD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Whether BI 706321 Combined With Ustekinumab Helps People With Crohn's Disease
Status: TERMINATED
Conditions: Crohn Disease
Interventions: DRUG: BI 706321|DRUG: ustekinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Addressing COVID-19 Vaccine Hesitancy With Muliti-Level Interventions in Appalachia
Status: ENROLLING_BY_INVITATION
Conditions: COVID-19|Vaccine Hesitancy
Interventions: BEHAVIORAL: Health Communication|BEHAVIORAL: Health Communication + Structural
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lymphokine-Activated Killer Cells or Gliadel Wafer in Treating Patients With Newly Diagnosed Glioblastoma Multiforme That Can Be Removed by Surgery
Status: WITHDRAWN
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: lymphokine-activated killer cells|DRUG: polifeprosan 20 with carmustine implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Giving Two Nucleoside Reverse Transcriptase Inhibitors Alone or in Combination With 141W94 to HIV-Infected Children Who Have Never Received Protease Inhibitors
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Amprenavir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of Intravenous Mircera (C.E.R.A or Methoxy Polyethylene Glycol-epoetin Beta) for the Maintenance Treatment of Hemodialysis Participants With Chronic Renal Anemia
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: methoxy polyethylene glycol-epoetin beta|DRUG: Epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pathogenesis of Uric Acid Nephrolithiasis: Role of Pioglitazone/Weight Loss
Status: RECRUITING
Conditions: Nephrolithiasis, Uric Acid
Interventions: DRUG: Pioglitazone 45 mg|BEHAVIORAL: Weight Loss|OTHER: Pioglitazone + Weight Loss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Urine-guided Hydration on Acute Kidney Injury After CRS-HIPEC
Status: RECRUITING
Conditions: Cytoreductive Surgery|Hyperthermic Intraperitoneal Chemotherapy|Hydration|Diuresis|Acute Kidney Injury|Postoperative Complications
Interventions: PROCEDURE: Urine-guided hydration|PROCEDURE: Routine hydration|DRUG: Forced administration of furosemide|DRUG: Routine administration of furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Compare the Bioavailability of Copegus and Vilona® in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: ribavirin [Copegus]|DRUG: ribavirin [Vilona]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: CoMBAT Opioid Use Disorder: A Combined Medication and Behavioral Activation Treatment for People Living With Opioid Use Disorder
Status: COMPLETED
Conditions: Opioid-use Disorder|Medication Adherence|Health Care Utilization
Interventions: BEHAVIORAL: Behavioral Activation (BA) Therapy|BEHAVIORAL: Substance Abuse and Health Navigation Counseling|OTHER: Medications for Opioid Use Disorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of 1000 Centistoke Versus 5000 Centistoke Silicone Oil for Repair of Complex Retinal Detachments
Status: COMPLETED
Conditions: Retinal Detachment|Vitrectomy|Proliferative Vitreoretinopathy|Diabetic Retinopathy
Interventions: PROCEDURE: 1000 centistoke silicone oil|PROCEDURE: 5000 centistoke silicone oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Dose Adjustment Schedule for Late Injection in SCIT in AR
Status: COMPLETED
Conditions: Allergic Rhinitis|Immunotherapy
Interventions: BIOLOGICAL: Novel dose adjustment of Alutard SQ|BIOLOGICAL: conventional dose adjustment of Alutard SQ|BIOLOGICAL: Routine continuous cluster of Alutard SQ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Patients With Diabetic Kidney Disease
Status: NOT_YET_RECRUITING
Conditions: Diabetic Kidney Disease
Interventions: DRUG: lisinopril, enalapril|DRUG: dapagliflozin, empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interferon-gamma as Adjunctive Therapy in Chronic Pulmonary Aspergillosis: a Randomised Feasibility Study
Status: RECRUITING
Conditions: Chronic Pulmonary Aspergillosis|Aspergillosis
Interventions: DRUG: Interferon Gamma-1B 0.1 MG Per 0.5 ML Injection PLUS antifungals as standard of care|DRUG: Antifungals as standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Abciximab, an Anti-platelet Therapy, in Patients Undergoing High-risk Coronary Angioplasty
Status: COMPLETED
Conditions: Angina, Unstable|Angioplasty, Transluminal, Percutaneous Coronary
Interventions: DRUG: Abciximab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Intralymphatic Allergen Immunotherapy Effective and Safe?
Status: COMPLETED
Conditions: Allergic Rhinitis Due to Grass Pollen
Interventions: DRUG: ALK Alutard 5-grasses|DRUG: ALK Diluent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of White Light on Fatigue Levels in Patients With Gynecological Cancer
Status: COMPLETED
Conditions: Cancer-related Fatigue|Light; Therapy, Complications
Interventions: OTHER: White Light Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Granisetron Extended Release Injection (GERSC) for the Prevention of Chemotherapy-induced Nausea and Vomiting
Status: WITHDRAWN
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: GRANISETRON EXTENDED RELEASE INJECTION (GERSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-course Radiotherapy Combined With Chemotherapy and Pd-1 Inhibitor for Locally Advanced Colon Cancer(TORCH-C)
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Colon Cancer
Interventions: DRUG: Serplulimab|RADIATION: short-term radiotherapy|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Percutaneous Tibial Nerve Stimulation With Solifenacin or Placebo to Treat Refractory Overactive Bladder
Status: TERMINATED
Conditions: Overactive Bladder
Interventions: OTHER: PTNS plus solifenacin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Night Splinting After Percutaneous Needle Fasciotomy in Dupuytren's Contracture
Status: RECRUITING
Conditions: Dupuytren Contracture|Dupuytren's Disease
Interventions: OTHER: No night splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Nexagon™ in the Treatment of Skin Wounds.
Status: COMPLETED
Conditions: Wound Healing
Interventions: DRUG: Nexagon™ or Nexagon™ vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dextromethorphan in Chemotherapy-induced Peripheral Neuropathy Management
Status: TERMINATED
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: DRUG: Dextromethorphan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: T-Regulatory Cell Infusion Post Umbilical Cord Blood Transplant in Patients With Advanced Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Multiple Myeloma|Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: umbilical cord blood transplantation|DRUG: Allopurinol|DRUG: fludarabine phosphate|DRUG: Cyclophosphamide|RADIATION: Total body irradiation|BIOLOGICAL: Treg infusion|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patients With Incomplete Colonoscopy a Comparison of Colon Capsule Endoscopy and CT Colonography
Status: COMPLETED
Conditions: Incomplete Colonoscopy|CT Colonography|Camera Capsule Endoscopy
Interventions: DEVICE: CCE in incomplete Colonoscopies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate the Efficacy, Safety and Tolerability of Everolimus in de Novo Renal Transplant Recipients Participating in the Eurotransplant Senior Program
Status: TERMINATED
Conditions: Renal Transplantation
Interventions: DRUG: Basiliximab|DRUG: Enteric Coated Mycophenolic Acid (MPA)|DRUG: RAD001|DRUG: Cyclosporin A (CsA)|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT