pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: To Demonstrate the Relative Bioequivalency of Cord's 100 mg Desipramine HCL Tablets To Merrell Dow's 100 mg Norpramin Tablets
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Desipramine HCL 100 mg Tablets Cord Laboratories|DRUG: Norpramin 100 mg Tablets Merrell Dow Pharmaceuticals, Inc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of 3D MR Neurogram for Intraparotid Facial Nerves Evaluation
Status: RECRUITING
Conditions: Parotid Neoplasms
Interventions: DIAGNOSTIC_TEST: Magnetic Resonance Imaging on 3T scanner (Magnetom Prisma, SIemens) with dedicated neurogram sequences (Constructive interference in steady state - CISS; Dual Echo Steady State - DESS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Fluzone® High-Dose Vaccine Compared With Fluzone® Vaccine In Elderly Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: High Dose Trivalent Inactivated Influenza Vaccine|BIOLOGICAL: Trivalent Inactivated Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Different Desensitizers in Reducing Dentinal Hypersensitivity
Status: UNKNOWN
Conditions: Dentine Hypersensitivity
Interventions: DRUG: 5% fluoride varnish|DRUG: 8% arginine containing paste|DRUG: Self-adhesive resin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Quantum NPWT With Simultaneous Irrigation on Reduction of Wound Volume in Stage III/IV Pressure Ulcers.
Status: UNKNOWN
Conditions: Pressure Ulcers
Interventions: DEVICE: Quantum Negative Pressure Wound Therapy Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Frequency and E-field Enhancement of ITBS for Depression (FREED)
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS) - Fully Individualized iTBS|DEVICE: Transcranial Magnetic Stimulation (TMS) - targeted-iTBS|DEVICE: Transcranial Magnetic Stimulation (TMS) - Standard-iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pomalidomide, Oral Dexamethasone and Very Low-dose Cyclophosphamide in Patients With Refractory Multiple Myeloma Who Have Received Lenalidomide and Bortezomib
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Pomalidomide + Cyclophosphamide + Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel Alone or in Combination With Vaccine to Treat Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel|BIOLOGICAL: PANVAC-V|BIOLOGICAL: PANVAC-F|BIOLOGICAL: Sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ⅱ Study of Adductor Canal Block With HR18034 for Postsurgical Pain Management
Status: ACTIVE_NOT_RECRUITING
Conditions: Total Knee Arthroplasty
Interventions: DRUG: HR18034;Ropivacaine Hydrochloride Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparison of Two Nebulisers for Sputum Induction
Status: UNKNOWN
Conditions: Asthma|COPD
Interventions: DEVICE: Omron NE-U17 Ultrasonic nebuliser|DEVICE: Akita Jet Inhalation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PRE-Pregnancy Weight Loss And the Reducing Effect on CHILDhood Overweight - Copenhagen
Status: RECRUITING
Conditions: Overweight and Obesity|Weight Loss|Pregnancy Related
Interventions: BEHAVIORAL: Weight loss intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Do the Head-elevated Position and the Use of a Videolaryngoscope Facilitate Orotracheal Intubation in a Patient Population Without Predictable Difficulty of Intubation
Status: RECRUITING
Conditions: Anesthesia
Interventions: DEVICE: Without RAMP and without video|DEVICE: With RAMP and with video|DEVICE: Without RAMP and with video|DEVICE: With RAMP and without video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Identification of Retinal Perivascular Inflammation in Patients With Multiple Sclerosis Using Adaptive Optics (RETIMUS)
Status: UNKNOWN
Conditions: Relapsing Remitting Multiple Sclerosis|Progressive Multiple Sclerosis|Optic Neuritis|Eye Diseases|Optic Nerve Diseases|Nervous System Diseases|Multiple Sclerosis
Interventions: OTHER: Adaptive Optics Ophthalmoscopy (AOO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Safety and Immunogenicity Study of IVACFLU-A/H5N1
Status: COMPLETED
Conditions: Avian Influenza
Interventions: BIOLOGICAL: IVACFLU-A/H5N1 vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 986 Administered Orally to Healthy Volunteers and Participants With Severely Impaired Renal Function
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: AMG 986
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Citalopram and Stress Reactivity
Status: UNKNOWN
Conditions: Depression|Depressive Disorder|Mental Disorder|Antidepressive Agents|Cognition|Stress
Interventions: DRUG: Citalopram|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lenvatinib and Everolimus in Treating Patients With Advanced, Unresectable Carcinoid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Carcinoid Tumor|Digestive System Neuroendocrine Neoplasm|Multiple Endocrine Neoplasia Type 1|Neuroendocrine Neoplasm|Unresectable Carcinoid Tumor
Interventions: DRUG: Everolimus|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of INGAP-Peptide in Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Insulin-Dependent
Interventions: DRUG: INGAP-Peptide|DRUG: INGAP-Peptide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ONO-1101 in Patients Scheduled for Coronary Angiography
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: ONO-1101|DRUG: ONO-1101|DRUG: ONO-1101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Study of Different Doses of Magnesium as a Protective Agent in Nephrotoxicity in Cancer Patients
Status: ENROLLING_BY_INVITATION
Conditions: Cisplatin Adverse Reaction
Interventions: DRUG: cisplatin with hydration magnesium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study to Compare Standard Perimetry With the New Scotoma-Oriented Perimetry (SCOPE) Using a New Fast German Adaptive Threshold Estimation (GATE) in Glaucoma Patients
Status: UNKNOWN
Conditions: Primary Open Angle Glaucoma (POAG)
Interventions: DEVICE: Perimetry|DEVICE: Confocal Scanning Laser Tomography|DEVICE: Optical Coherence Tomography (OCT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Therapeutic Effect of Bandage Contact Lenses ( BCL) on Dry Eye Caused by Sjogren's Syndrome
Status: COMPLETED
Conditions: Sjögren's Syndrome Patients With Severe Dry Eye
Interventions: DRUG: 0.02% Fm, SH|DRUG: 0.02% Fm, SH, 0.05% CsA|OTHER: 0.02% Fm, SH, tBCL|DRUG: 0.02% Fm, SH, AS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Speed of Increasing Milk Feeds Trial
Status: COMPLETED
Conditions: Premature Birth|Late-onset Invasive Infection|Necrotizing Enterocolitis
Interventions: DIETARY_SUPPLEMENT: Milk feed (breast milk or formula milk)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SUrGery With or Without dARolutamide in High-risk and/or Locally Advanced Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: OTHER: Surgery alone|DRUG: Peri-operative darolutamide + surgery.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Half-Somersault Exercise With Brandt-Daroff Exercise in BPPV.
Status: COMPLETED
Conditions: Vertigo, Paroxysmal
Interventions: OTHER: Group I Brandt-Daroff Exercises|OTHER: Group II Half-Somersault Maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness & Implementation of a Behavioral Intervention for Adherence and Substance Use in HIV Care in South Africa
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|Alcohol-Related Disorders|Drug Use
Interventions: BEHAVIORAL: Project Khanya
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Energy Expenditure Assessment of Premature Infants
Status: COMPLETED
Conditions: Weight
Interventions: OTHER: energy expenditure in preterm fed with preterm formula|OTHER: assessment of energy expenditure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Levofloxacin for the Treatment of Sinus Infections in Adults
Status: COMPLETED
Conditions: Maxillary Sinusitis
Interventions: DRUG: azithromycin SR (Zithromax; compound: CP-62,993)|OTHER: placebo|DRUG: levofloxacin|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Transplantation of BM-ECs With Platelet-Rich Plasma Extract for the Treatment of Critical Limb Ischemia
Status: UNKNOWN
Conditions: Leg Ulcer|Diabetic Foot|Gangrene|Peripheral Vascular Disease|Ischemia
Interventions: BIOLOGICAL: BM-ECs and PRPE|BIOLOGICAL: BM-ECs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Erector Spinae Infusion Versus Thoracic Epidural for Patients With Upper Abdominal Cancer Surgeries
Status: COMPLETED
Conditions: Pain Relief in Upper Abdominal Cancer Surgeries
Interventions: PROCEDURE: erector spinae block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Safety, Pharmacokinetic, and Tolerability Study of Zecuity® in Adolescent Subjects With a History of Acute Migraine
Status: COMPLETED
Conditions: Acute Migraine
Interventions: DRUG: PROT-CL-NP101-015.01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transfusion of Fresh Frozen Plasma in Non-bleeding Intensive Care Unit (ICU) Patients
Status: COMPLETED
Conditions: Blood Coagulation Disorders|Hemorrhage
Interventions: OTHER: omitting FFP transfusion before an intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Correction of Metabolic Acidosis in CKD on Intrarenal RAS Activity
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: Sodium bicarbonate|DIETARY_SUPPLEMENT: Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Oral Ceritinib in Patients With ALK and ROS1 Activated Gastrointestinal Malignancies
Status: TERMINATED
Conditions: Colorectal Adenocarcinoma|Cholangiocarcinoma|Pancreatic Adenocarcinoma|Hepatocellular Adenocarcinoma|Gastric Adenocarcinoma|Esophageal Adenocarcinoma
Interventions: DRUG: ceritinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effects of Lipid-therapy Intensification With Alirocumab on Endothelial Function, Carotid Arteries, Lipoprotein Particle Subfractions, Inflammation and Post-prandial Lipemia
Status: TERMINATED
Conditions: Atherosclerosis|Hypercholesterolemia|Post Prandial Lipemia|Cardiovascular Diseases
Interventions: DIAGNOSTIC_TEST: Magnet Resonance Tomography, Carotid Arteries Sonography, Flow-mediated Dilation, Fat-tolerance Test, Laboratory Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Staged Angioplasty and Routine Single-stage Stenting (CAS) in the Treatment of Carotid Artery Stenosis
Status: UNKNOWN
Conditions: Carotid Artery Stenosis
Interventions: DEVICE: Abbott EPD systems (Accunet/Emboshield), a balloon, stent|DEVICE: a balloon, stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Helicobacter Pylori and Its Toxins in Lung and Digestive System Diseases
Status: COMPLETED
Conditions: Pulmonary Disease|Oropharyngeal Disease|Lymphangioleiomyomatosis|Pulmonary Fibrosis|Asthma|Sarcoidosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Semi-automatic assessMent of Aortic Roots by Three-dimensional transoEsophageal echocaRdiography (SMARTER)
Status: COMPLETED
Conditions: Aortic Valve Disease
Interventions: PROCEDURE: Three-dimensional transoesophageal echocardiography|PROCEDURE: Computed tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess VPM1002 in Reducing Healthcare Professionals' Absenteeism in COVID-19 Pandemic
Status: UNKNOWN
Conditions: Infection, Respiratory Tract
Interventions: BIOLOGICAL: VPM1002|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: GH in Adults With PWS, Effect on Hypotonia Evaluated by Functional MRI, Relationship With Strength and Body Composition
Status: COMPLETED
Conditions: Prader-Willi Syndrome
Interventions: DRUG: Growth hormone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Choroidal and Retinal Changes After RLRL Therapy in Diabetes and Diabetic Retinopathy
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2|Diabetic Retinopathy
Interventions: DEVICE: RLRL device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interventions for Unemployed Hazardous Drinkers
Status: COMPLETED
Conditions: Unemployment|Hazardous Drinking
Interventions: BEHAVIORAL: Contingency management for alcohol abstinence|BEHAVIORAL: Contingency management for completing job related activities|BEHAVIORAL: Job relelated activity contracting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychological Mobile Interventions to Reduce Distress
Status: RECRUITING
Conditions: Psychological Distress
Interventions: BEHAVIORAL: PsyPills|BEHAVIORAL: Online-Contingent Attention Training, OCAT|BEHAVIORAL: shamOCAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Effectiveness and Complications of Catheter Lock Solutions in Non-tunneled Hemodialysis Catheters
Status: COMPLETED
Conditions: Catheter Blockage|Catheter-Related Infections|Dialysis Catheter; Thrombosis|Catheter Infection|Catheter Related Complication|Catheter Dysfunction
Interventions: DRUG: Sodium bicarbonate|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nutrition Optimalization Among Pregnant Women to Improve Maternal and Neonatal Outcome in DKI Jakarta
Status: RECRUITING
Conditions: Pregnancy Complications|Maternal Death|Preeclampsia|Intrauterine Infection|Pregnancy Hemorrhage|Preterm Birth|Neonatal Death|Low; Birthweight, Extremely (999 Grams or Less)|Asphyxia Neonatorum|IUGR
Interventions: DIAGNOSTIC_TEST: Nutritional panel laboratory examination|DIETARY_SUPPLEMENT: Pregnancy supplements (other than provided by Ministry of Health)|DIAGNOSTIC_TEST: Fetomaternal ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Biomedicines and Bacterial Translocation in Spondyloarthritis
Status: RECRUITING
Conditions: Axial Spondyloarthritis
Interventions: OTHER: Blood sample|DRUG: anti-TNF antibody administration|DRUG: anti-IL-17 antibody administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hypoglycemic Effects of Fermented Red Ginseng in Subject With Impaired Fasting Glucose or Type 2 Diabetes
Status: COMPLETED
Conditions: Impaired Glucose or Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Fermented Red Ginseng|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Physiotherapy and Psychological Among Refugees From Syria
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain|Mental Health Impairment
Interventions: BEHAVIORAL: Physiotherapy activity and awareness intervention: PAAI|BEHAVIORAL: Psychological intervention: Teaching recovery techniques (TRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recovery of Bladder and Sexual Function After Human Spinal Cord Injury
Status: RECRUITING
Conditions: Urinary Bladder, Neurogenic|Blood Pressure|Autonomic Dysreflexia|Bowel Incontinence
Interventions: DEVICE: Spinal Cord Epidural Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ROCO - Self-help for People With Psychological Distress Due to the Covid-19 Situation
Status: COMPLETED
Conditions: Psychological Distress|Adjustment, Psychological|Coronavirus
Interventions: BEHAVIORAL: Internet-based self-help|BEHAVIORAL: Internet-based self-help after 3 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of (Neo)Adjuvant V940 and Pembrolizumab in Cutaneous Squamous Cell Carcinoma (V940-007)
Status: RECRUITING
Conditions: Carcinoma, Squamous Cell|Skin Neoplasms
Interventions: BIOLOGICAL: Pembrolizumab|BIOLOGICAL: V940|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Elimination or Prolongation of ACE Inhibitors and ARB in Coronavirus Disease 2019
Status: COMPLETED
Conditions: COVID-19
Interventions: OTHER: Discontinuation of ARB/ACEI|OTHER: Continuation of ARB/ACEI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Evaluate the Self-Management of Gait, Speech, and Dexterity Symptoms in Parkinson's Disease Using a Smartphone Application
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DEVICE: Parkinson's Application|DEVICE: Digital Placebo Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetics Study of Favipiravir in Patients With Severe Influenza
Status: COMPLETED
Conditions: Influenza, Human|Critical Illness|Influenza
Interventions: DRUG: Favipiravir|DRUG: Oseltamivir 75Mg Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study of PORT-77 Administered to Healthy Adult Participants
Status: NOT_YET_RECRUITING
Conditions: Healthy Adult Participants
Interventions: DRUG: PORT-77|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Saracatinib in Treating Patients With Relapsed or Refractory Thymoma or Thymic Cancer
Status: TERMINATED
Conditions: Invasive Thymoma and Thymic Carcinoma|Recurrent Thymoma and Thymic Carcinoma|Stage III Thymoma|Stage IVA Thymoma|Stage IVB Thymoma
Interventions: DRUG: saracatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dilapan-S®: A Multicenter US E-registry
Status: ENROLLING_BY_INVITATION
Conditions: Post Term Pregnancy|Premature Rupture of Membrane|Fetal Growth Retardation|Oligohydramnios|Gestational Diabetes|High Blood Pressure in Pregnancy
Interventions: DEVICE: Dilapan-S
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Magnevist® Injection Enhanced MRA Compared to Non Contrast MRA for the Detection of Structural Abnormalities of the Aortic Arch and Cerebral Branches
Status: COMPLETED
Conditions: Cardiovascular Abnormalities
Interventions: DRUG: Gadopentetate dimeglumine (Magnevist)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Local Effects of Epinephrine on Lactate, Glucose, Lipid and Protein Metabolism in Bilaterally Perfused Human Legs
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Catheter Size on Peri-Operative Pain After Robotic Assisted Laparoscopic Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DEVICE: 16 French urinary catheter|DEVICE: 20 French urinary catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effects of Non-ablative Radiofrequency on Female Genito-pelvic Pain Disorder
Status: RECRUITING
Conditions: Pelvic Pain
Interventions: DEVICE: nonablative radiofrequency|DEVICE: Vaginal dilator|DEVICE: Sham nonablative radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IVES for Treatment of UUI and OAB
Status: COMPLETED
Conditions: Urinary Bladder, Overactive|Urinary Incontinence, Urge
Interventions: DEVICE: EMED detruset(TM) intravesical electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial In Diabetic Patients To Assess Effect Of CE-326,597 On Glucose Control And Body Weight
Status: COMPLETED
Conditions: Weight Management|Treatment Of Obesity
Interventions: DRUG: CE-326,597 100 mg QD|DRUG: CE-326,597 50 mg QD|DRUG: CE-326,597 25 mg QD|DRUG: Placebo|DRUG: CE-326,597 5mg QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Neuromuscular Block on Cytokines Release and Postoperative Delirium
Status: COMPLETED
Conditions: Hip Fractures
Interventions: OTHER: Moderate neuromuscular blockade|OTHER: Deep neuromuscular blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate Safety, Tolerability and Pharmacokinetics of Oral ZYGK1 in Healthy Volunteers
Status: SUSPENDED
Conditions: Diabetes
Interventions: DRUG: ZYGK1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LYR-210 Depot (LYR-210) for Adult Subjects With Chronic Sinusitis (LANTERN Study)
Status: COMPLETED
Conditions: Chronic Sinusitis|Chronic Rhinosinusitis (Diagnosis)
Interventions: DRUG: LYR-210|OTHER: Sham comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Alisertib in Combination With Vorinostat in Treating Patients With Relapsed or Recurrent Hodgkin Lymphoma, B-Cell Non-Hodgkin Lymphoma, or Peripheral T-Cell Lymphoma
Status: COMPLETED
Conditions: Adult B Acute Lymphoblastic Leukemia|Adult T Acute Lymphoblastic Leukemia|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-Cell Lymphoma|Chronic Lymphocytic Leukemia|Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue|Hepatosplenic T-Cell Lymphoma|Intraocular Lymphoma|Lymphomatous Involvement of Non-Cutaneous Extranodal Site|Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma|Nodal Marginal Zone Lymphoma|Primary Cutaneous B-Cell Non-Hodgkin Lymphoma|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult T-Cell Leukemia/Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides and Sezary Syndrome|Recurrent Non-Hodgkin Lymphoma|Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Hairy Cell Leukemia|Small Intestinal Lymphoma|Splenic Marginal Zone Lymphoma|T-Cell Large Granular Lymphocyte Leukemia|Testicular Lymphoma|Waldenstrom Macroglobulinemia
Interventions: DRUG: Alisertib|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sunitinib Before or After Surgery in Treating Patients With Metastatic Kidney Cancer
Status: UNKNOWN
Conditions: Kidney Cancer
Interventions: DRUG: sunitinib malate|PROCEDURE: adjuvant therapy|PROCEDURE: neoadjuvant therapy|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Extensive Intraoperative Peritoneal Lavage After Curative Gastrectomy for Locally Advanced Gastric Cancer (SEIPLUS)
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: OTHER: Extensive Intraoperative Peritoneal Lavage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Second-line Treatment With Apatinib After TACE in Advanced Hepatocellular Carcinoma Patients
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy, Total-Body Irradiation, and Alemtuzumab in Treating Patients Undergoing an Autologous Stem Cell Transplant for Stage I, Stage II, Stage III, or Stage IV Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: alemtuzumab|BIOLOGICAL: filgrastim|DRUG: carmustine|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: dexamethasone|DRUG: etoposide|DRUG: fludarabine phosphate|DRUG: melphalan|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of the Ultrasound Guidance for the Laying of Femoral Arterial and Venous Catheters in Intensive Care Unit
Status: COMPLETED
Conditions: Severely Traumatized Patients in Emergency Wards
Interventions: PROCEDURE: venous and arterial catheter set-up using ultrasound guidance|PROCEDURE: Anatomical guidance.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Longan and Lingzhi Mushroom Syrup on Immune and Inflammatory Responses in Healthy Volunteers
Status: COMPLETED
Conditions: Safety Issues
Interventions: DIETARY_SUPPLEMENT: Longan and lingzhi mushroom syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Chemotherapy of Nanoparticle Albumin-bound Paclitaxel in Lung Cancer
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: nanoparticle albumin-bound paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of Exablate Blood-Brain Barrier Disruption for Mild Cognitive Impairment or Mild Alzheimer's Disease Undergoing Standard of Care Monoclonal Antibody (mAb) Therapy
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Alzheimer Disease 1
Interventions: DRUG: Aducanumab|DEVICE: Exablate Model 4000 Type 2|DRUG: Lecanemab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Safety and Immunogenicity of CodaVax-RSV in Seropositive and Seronegative Children
Status: RECRUITING
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: CodaVax-RSV|BIOLOGICAL: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: FAecal Microbiota Transplantation in primaRy sclerosinG chOlangitis
Status: RECRUITING
Conditions: Primary Sclerosing Cholangitis|Inflammatory Bowel Diseases
Interventions: BIOLOGICAL: Faecal Microbiota Transplant|OTHER: FMT Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Precision Medicine Approach for Osteoporosis - Follow Up Study
Status: ENROLLING_BY_INVITATION
Conditions: Osteoporosis
Interventions: DRUG: Alendronate|DRUG: Teriparatide|DRUG: Alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of TPOXX When Administered Orally for 28 Days
Status: COMPLETED
Conditions: Smallpox
Interventions: DRUG: TPOXX|OTHER: TPOXX Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Oxycodone-propofol Combination Compared With a Fentanyl-propofol Combination on Conscious Sedation Effect and Early Cognitive Function During Therapeutic Endoscopic Retrograde Cholangio-pancreatography
Status: UNKNOWN
Conditions: Conscious Sedation During Endoscopic Retrograde Choledochopancreatography
Interventions: DRUG: Oxycodone|DRUG: fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Afolabi Stroke Registry for Children and Young Adults With SCD in Northern Nigeria
Status: COMPLETED
Conditions: Sickle Cell Disease|Stroke|Neurologic Manifestations|Neurological Morbidity|Sickle Cell Anemia in Children|Sickle Cell Anemia
Interventions: OTHER: This study does not entail offering any intervention; all data collected will be based on standard of care.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM)
Status: RECRUITING
Conditions: Ciliopathies|Nephronophthisis|Senior-Loken Syndrome|Joubert Syndrome|Jeune Syndrome|Bardet-Biedl Syndrome
Interventions: OTHER: Blood sample|OTHER: Urine sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer
Status: RECRUITING
Conditions: Stage III Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer|Invasive Breast Carcinoma|Recurrent Breast Carcinoma|Triple-Negative Breast Carcinoma|Unresectable Breast Carcinoma
Interventions: BIOLOGICAL: Anti-OX40 Antibody PF-04518600|DRUG: Avelumab|DRUG: Binimetinib|BIOLOGICAL: Utomilumab|DRUG: Liposomal Doxorubicin|DRUG: Sacituzumab Govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimally INvasive Colon Cancer Surgery Through IMmunomics and Optical Mapping of the Sentinel Lymph Node.
Status: RECRUITING
Conditions: Colon Cancer|Sentinel Lymph Node
Interventions: OTHER: ICG-nanocoll (indocyanine green coupled to the human albumin colloidal particle nanocoll)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Remote Ischemic Conditioning and Dynamic Cerebral Autoregulation in Patients With Intracranial and Extracranial Arteriosclerosis
Status: RECRUITING
Conditions: Carotid Stenosis|Ischemic Stroke
Interventions: PROCEDURE: remote ischemic conditioning|PROCEDURE: sham remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NESC: Neoadjuvant Treatment Of Gastric Adenocarcinoma
Status: UNKNOWN
Conditions: Gastric Adenocarcinoma
Interventions: DRUG: Docetaxel - Cisplatine - 5FU|RADIATION: Radiation of 45 Grays on 5 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Maintenance Treatment With TALAzoparib Following First Line Platinum-based Chemotherapy in Malignant MESOthelioma
Status: NOT_YET_RECRUITING
Conditions: Advanced Malignant Pleural or Peritoneal Mesothelioma
Interventions: DRUG: Talazoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma, Soft Tissue|Soft Tissue Sarcoma|Undifferentiated Pleomorphic Sarcoma|Leiomyosarcoma|Liposarcoma|Synovial Sarcoma|Myxofibrosarcoma|Angiosarcoma|Fibrosarcoma|Malignant Peripheral Nerve Sheath Tumor|Epithelioid Sarcoma
Interventions: DRUG: Dexrazoxane|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accelerated Brachytherapy Forward Chemo Radiation Therapy (ABC-RT) for Locally-advanced Cervical Cancer
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Cervical Carcinoma
Interventions: RADIATION: Hypofractionated external beam radiation|DRUG: Chemotherapy|RADIATION: Image-guided brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Frontline Immunotherapy Combined With Radiation and Chemotherapy in High Risk Endometrial Cancer
Status: RECRUITING
Conditions: Endometrial Cancer
Interventions: DRUG: Pembrolizumab|RADIATION: Vaginal cuff brachytherapy (VCB)|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D3 Supplementation in Participants Diagnosed With Early-Stage Prostate Cancer Who Decide to Undergo Active Surveillance Treatment Regimen.
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: cholecalciferol|DIETARY_SUPPLEMENT: cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Melatonin Treatment on Bone, Marrow, Sleep and Blood Pressure
Status: UNKNOWN
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: Melatonin 10 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab in Combination With Apatinib Plus NK Cell for Advanced HCC
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Apatinib|DRUG: Camrelizumab|DRUG: NK cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Budesonide Nasal Instillation in a Vertex-to-floor Position
Status: UNKNOWN
Conditions: Chronic Frontal Rhinosinusitis|Vertex to Floor Position
Interventions: DRUG: Budesonide nasal instillation|DRUG: Normal saline nasal instillation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ETAPA I: Peptide-based Tumor Associated Antigen Vaccine in GBM
Status: RECRUITING
Conditions: Glioma, Malignant
Interventions: BIOLOGICAL: Tumor Associated Antigen Peptide Vaccine P30-EPS Vaccine|DRUG: Hiltonol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Karajishi Contour Investigational Blood Glucose Monitoring System (ISO/FDA Study)
Status: COMPLETED
Conditions: Diabetes
Interventions: DEVICE: Subjects WITH/WITHOUT Diabetes Use Karajishi Contour BGMS|DEVICE: Subjects WITH Diabetes Use Karajishi Contour BGMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical and Mechanistic Study of Patients (With COVID-19 or Not) With a Recent Acrosyndrome
Status: NOT_YET_RECRUITING
Conditions: Adult Patients With Lesions on Fingers or Toes
Interventions: OTHER: Blood sampling|OTHER: Skin biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of PROVIGIL ® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea Syndrome
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DRUG: Modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Efficacy of Vardenafil in Subjects With Erectile Dysfunction and Diabetes, Hypertension or Hyperlipidemia
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Tadalafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COMPression of Left Main coRonary artEry in patientS With Pulmonary Arterial Hypertension aSymptomatIc fOr aNgina
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: RADIATION: Coronary CT angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pazopanib Hydrochloride Followed by Chemotherapy and Surgery in Treating Patients With Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Stage IIA Adult Soft Tissue Sarcoma|Stage III Adult Soft Tissue Sarcoma|Stage IV Adult Soft Tissue Sarcoma
Interventions: DRUG: Doxorubicin Hydrochloride|RADIATION: External Beam Radiation Therapy|DRUG: Ifosfamide|OTHER: Laboratory Biomarker Analysis|DRUG: Pazopanib Hydrochloride|OTHER: Pharmacological Study|OTHER: Placebo|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: D-Serine Treatment of Negative Symptoms and Cognitive Deficits in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: D-serine|BEHAVIORAL: Cognitive Retraining (CRT)|DRUG: Placebo|BEHAVIORAL: Cognitive Retraining Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Study of UCB4940 as add-on to Certolizumab Pegol in Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Bimekizumab|BIOLOGICAL: Certolizumab Pegol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Intervention Programme to Reduce Cognitive Impairment Due to Cancer
Status: TERMINATED
Conditions: Breast Neoplasms|Colorectal Neoplasms
Interventions: BEHAVIORAL: Countering cognitive impairment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison Between Immediate and Gradual Decannulation
Status: UNKNOWN
Conditions: Tracheostomy
Interventions: OTHER: Overnight observation|OTHER: Pre-discharge evaluation|OTHER: outpatient clinic follow ups|PROCEDURE: immediate decannulation|PROCEDURE: Gradual tracheostomy tube decrease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Relining Versus Digital Altered Cast Using Digitally Fabricated Distal Extension Frameworks
Status: ENROLLING_BY_INVITATION
Conditions: Dental Prosthesis Complication
Interventions: PROCEDURE: Removable partial denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Blood Volume Analysis of Total Hip Arthroplasty Patients Under Hypotensive Anesthesia
Status: COMPLETED
Conditions: Blood Volume Analysis
Interventions: RADIATION: 1mL of I-131 Human Serum Albumin is injected prior to the measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Neurotidine® Intake on Life Quality of Patients With Glaucoma
Status: COMPLETED
Conditions: Glaucoma
Interventions: OTHER: Food for special medical purposes: Neurotidine®|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intrapartum Epidural Fentanyl and Breastfeeding in the Immediate Postpartum Period: a Randomized, Controlled, Double-blinded Study
Status: WITHDRAWN
Conditions: Neonatal Neurobehavior|Breastfeeding Outcomes
Interventions: DRUG: Bolus 10mL 0.25% bupivacaine/ep 1:600,000; infusion 10mL/hour 0.25% bupivacaine and epi 1:800,000|DRUG: Bolus 10mL 0.25% bupivacaine/ epinephrine 1:600,000;infusion 10mL/hour 0.25% bupivacaine, 2 mcg/mL fentanyl, and epinephrine 1:800,000|DRUG: Bolus 10mL 0.25% bupivacaine, 10mcg/mL fentanyl, and epi 1:600,000; infusion 10mL/hour 0.25% bupivacaine, 2.5 mcg/mL fentanyl, and epi 1:800,000|DRUG: Bolus 10mL 0.25% bupivacaine, 5 mcg/mL fentanyl, and epi 1:600,000; infusion 10mL/hour 0.25% bupivacaine, 3.5 mcg/mL fentanyl, and epi 1:800,000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors
Status: RECRUITING
Conditions: Colorectal Neoplasms|Carcinoma, Non-Small-Cell Lung|Exocrine Pancreatic Cancer|Carcinoma, Squamous Cell of Head and Neck
Interventions: DRUG: tisotumab vedotin|DRUG: pembrolizumab|DRUG: carboplatin|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT